CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007572	Streptococcus agalactiae strain GBS6 chromosome, complete genome	3 crisprs	RT,cas3,DinG,cas9,cas1,cas2,csn2,csm6,DEDDh,csa3	1	7	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007572_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007572_1

998542-998766

TypeII

II-A

Consensus_repeat	Method
GGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	CRISPRCasFinder
GGTTTTAGAGCTGTGCTGTTTCGAATG	CRT

3 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NZ_CP007572_1

>merge|NZ_CP007572|1|998542-998766|CRISPRCasFinder,CRT
GGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTGCAATGTTATTTGATGATGGAACAACATGGTTTTAGAGCTGTGCTGTTTCGAATGATTCCAAAACAATACAATAGTCGCACAAACAGCGAACAGTGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAACTTTAATATCGTCTATATAGATTCCTGGACGGTTTTAGAGCTGCGCGGTTATTATGC

>NZ_CP007572|1|1|998542-998710|CRISPRCasFinder
GGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC	TGCAATGTTATTTGATGATGGAACAACAT
GGTTTTAGAGCTGTGCTGTTTCGAATGATTCCAAAAC	AATACAATAGTCGCACAAACAGCGAACAG
TGTTTTAGAGCTGTGCTGTTTCGAATGGTTCCAAAAC

>NZ_CP007572|1|1|998542-998766|CRT
GGTTTTAGAGCTGTGCTGTTTCGAATG	GTTCCAAAACTGCAATGTTATTTGATGATGGAACAACAT
GGTTTTAGAGCTGTGCTGTTTCGAATG	ATTCCAAAACAATACAATAGTCGCACAAACAGCGAACAG
TGTTTTAGAGCTGTGCTGTTTCGAATG	GTTCCAAAACTTTAATATCGTCTATATAGATTCCTGGAC
GGTTTTAGAGCTGCGCGGTTATTATGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007572.1\|WP_000122194.1\|997448_997790_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP007572.1\|WP_001040096.1\|992468_996581_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NZ_CP007572.1\|WP_000678289.1\|1001946_1004580_+\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|380193
NZ_CP007572.1\|WP_000929489.1\|996582_997452_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP007572.1\|WP_041326298.1\|987162_988608_-\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|226192
NZ_CP007572.1\|WP_000621143.1\|1005347_1005812_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_CP007572.1\|WP_000438313.1\|999316_999733_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NZ_CP007572.1\|WP_001241816.1\|986771_987152_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131381
NZ_CP007572.1\|WP_001019128.1\|999868_1001701_+\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NZ_CP007572.1\|WP_000065324.1\|1009190_1010294_+\|DUF2974-domain-containing-protein	unknown	unknown	gnl\|CDD\|371412
NZ_CP007572.1\|WP_001056394.1\|1013298_1013910_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NZ_CP007572.1\|WP_000665410.1\|1005811_1006246_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NZ_CP007572.1\|WP_000180011.1\|1004679_1005339_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224336
NZ_CP007572.1\|WP_000168908.1\|1006398_1009191_+\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NZ_CP007572.1\|WP_000146568.1\|1010412_1011051_-\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NZ_CP007572.1\|WP_000523795.1\|989938_990676_+\|acyl-ACP-thioesterase	unknown	unknown	gnl\|CDD\|366738
NZ_CP007572.1\|WP_000323544.1\|990676_991447_+\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NZ_CP007572.1\|WP_000914659.1\|988804_989935_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_CP007572.1\|WP_000653355.1\|991436_992093_+\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NZ_CP007572.1\|WP_000590703.1\|997776_998442_+\|type-II-A-CRISPR-associated-protein-Csn2	csn2	pfam09711_csn2_CAS-II-A	gnl\|CDD\|213408

Protein	Function_ID	Function_description	E-value
NZ_CP007572.1\|WP_000122194.1\|997448_997790_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	2.38084e-52
NZ_CP007572.1\|WP_001040096.1\|992468_996581_+\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NZ_CP007572.1\|WP_000678289.1\|1001946_1004580_+\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|380193	NF033189, internalin_A, class 1 internalin InlA. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface or secreted proteins with an N-terminal signal peptide, leucine-rich repeats, and usually a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin A (InlA), a class 1 (LPXTG-type) internalin.	5.90067e-22
NZ_CP007572.1\|WP_000929489.1\|996582_997452_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	2.54315e-139
NZ_CP007572.1\|WP_041326298.1\|987162_988608_-\|IS1182-family-transposase	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.37658e-28
NZ_CP007572.1\|WP_000621143.1\|1005347_1005812_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.29827e-18
NZ_CP007572.1\|WP_000438313.1\|999316_999733_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	6.25805e-79
NZ_CP007572.1\|WP_001241816.1\|986771_987152_+\|hypothetical-protein	gnl\|CDD\|131381	TIGR02328, TIGR02328, conserved hypothetical protein. Members of this protein are found in a small number of taxonomically well separated species, yet are strongly conserved, suggesting lateral gene transfer. Members are found in Treponema denticola, Clostridium acetobutylicum, and several of the Firmicutes. The function of this protein is unknown. [Hypothetical proteins, Conserved].	6.45558e-80
NZ_CP007572.1\|WP_001019128.1\|999868_1001701_+\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NZ_CP007572.1\|WP_000065324.1\|1009190_1010294_+\|DUF2974-domain-containing-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	2.245e-105
NZ_CP007572.1\|WP_001056394.1\|1013298_1013910_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	6.1265e-31
NZ_CP007572.1\|WP_000665410.1\|1005811_1006246_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	6.40832e-86
NZ_CP007572.1\|WP_000180011.1\|1004679_1005339_+\|HD-domain-containing-protein	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	2.46285e-32
NZ_CP007572.1\|WP_000168908.1\|1006398_1009191_+\|cation-transporting-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NZ_CP007572.1\|WP_000146568.1\|1010412_1011051_-\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	2.15538e-71
NZ_CP007572.1\|WP_000523795.1\|989938_990676_+\|acyl-ACP-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	3.68196e-111
NZ_CP007572.1\|WP_000323544.1\|990676_991447_+\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19143e-132
NZ_CP007572.1\|WP_000914659.1\|988804_989935_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_CP007572.1\|WP_000653355.1\|991436_992093_+\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	8.37758e-51
NZ_CP007572.1\|WP_000590703.1\|997776_998442_+\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	4.68487e-122

>NZ_CP007572.1|WP_000590703.1|997776_998442_+|type-II-A-CRISPR-associated-protein-Csn2
MIKINFPILDEPLVLSNATILTIEDVSVYSSLVKHFYQYDVDEHLKLFDDKQKSLKAAELMLVTDILGYDVNSAPILKLIHGDLENQFNEKPEVKSMVEKLAATITELIAFECLENELDLEYDEITILELIKALGVKIETQSDTIFEKCFEIIQVYHYLTKKNLLVFVNSGAYLTKDEVIKLCEYINLMQKSVLFLEPRRLYDLPQYVIDKDYFLIGENMV
>NZ_CP007572.1|WP_000122194.1|997448_997790_+|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNTANNAMIGRLKVNNPKKGNITLLTVTEKQFARMVYLHGERNTSVANSDSRLVFLGDSYDQD
>NZ_CP007572.1|WP_000929489.1|996582_997452_+|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDSYQTEMIHLSEIDILIMETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARHDSSLQLSRQMSWIEDVKADVWTSIIAQKILNQSFYLGECSFFEKSQSIMNLYHDLEPFDPSNREGHAARIYFNTLFGNDFSREQDNPINAGLDYGYSLLLSMFAREVVKCGCMTQFGLKHANQFNQFNLASDIMEPFRPIVDRIIYENRQSDFVKMKRELFSMFSETYSYNGKEMYLSNIVSDYTKKVIKSLNSDGNGIPEFRI
>NZ_CP007572.1|WP_001040096.1|992468_996581_+|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNKPYSIGLDIGTNSVGWSIITDDYKVPAKKMRVLGNTDKEYIKKNLIGALLFDGGNTAADRRLKRTARRRYTRRRNRILYLQEIFAEEMSKVDDSFFHRLEDSFLVEEDKRGSKYPIFATMQEEKYYHEKFPTIYHLRKELADKKEKADLRLIYLALAHIIKFRGHFLIEDDRFDVRNTDIQKQYQAFLEIFDTTFENNDLLSQNVDVEAILTDKISKSAKKDRILARYPNQKSTGIFAEFLKLIVGNQADFKKHFNLEDKTPLQFAKDSYDEDLENLLGQIGDEFADLFSAAKKLYDSVLLSGILTVTDLSTKAPLSASMIQRYDEHREDLKQLKQFVKASLPEKYQEIFADSSKDGYAGYIEGKTNQEAFYKYLSKLLTKQEGSEYLLEKIKNEDFLRKQRTFDNGSIPHQVHLTELRAIIRRQSEYYPFLKENLDRIEKILTFRIPYYVGPLAREKSDFAWMTRKTDDSIRPWNFEDLVDKEKSAEAFIHRMTNNDLYLPEEKVLPKHSLIYEKFTVYNELTKVRFLAEGFKDFQFLNRKQKETIFNSLFKEKRKVTEKDIISFLNKVDGYEGIAIKGIEKQFNASLSTYHDLKKILGKDFLDNTDNELILEDIVQTLTLFEDREMIRKRLDIYKDFFTESQLKKLYRRHYTGWGRLSAKLINGIRNKENQKTILDYLIDDGSANRNFMQLIKDAGLSFKPIIDKARTGSHLDNLKEVVGELAGSPAIKKGILQSLKIVDELVKVMGYEPEQIVVEMARENQTTAKGLSRSRQRLTTLRESLANLKSNILEEKKPKYVKDQVENHHLSDDRLFLYYLQNGKDMYTDDELDIDNLSQYDIDHIIPQAFIKDDSIDNRVLVSSAKNRGKSDDVPSLEIVKDCKVFWKKLLDAKLMSQRKYDNLTKAERGGLTSDDKARFIQRQLVETRQITKHVARILDERFNNELDSKGRRIRKVKIVTLKSNLVSNFRKEFGFYKIREVNNYHHAHDAYLNAVVAKAILTKYPQLEPEFVYGDYPKYNSYKTRKSATEKLFFYSNIMNFFKTKVTLADGTVVVKDDIEVNNDTGEIVWDKKKHFATVRKVLSYPQVNIVKKTEVQTGGFSKESILAHGNSDKLIPRKTKDIYLDPKKYGGFDSPIVAYSVLVVADIKKGKAQKLKTVTELLGITIMERSRFEKNPSAFLESKGYLNIRTDKLIILPKYSLFELENGRRRLLASAGELQKGNELALPTQYMKFLYLASRYNELKGKPEEIEQKQEFVVQHVSYFDDILQIINDFSNRVILADANLEKINKLYQDNKENIPVDELANNIINLFTFTSLGAPAAFKFFDKIVDRKRYTSTKEVLNSTLIHQSITGLYETRIDLGKLGEG
>NZ_CP007572.1|WP_000653355.1|991436_992093_+|TIGR01906-family-membrane-protein
MKDKLLVVLTWIWIISLATLATIYIAWLIYPIEIQFLKLEKVVYLKAETIYYNFNKLMIYLTHPFISDLNMPSFPSSEDGLKHFADVKYLFTLAHGLFVILTFPVIYFLRHGWKQKSIFLYEGFFKIAIMLPIFIVVCAFLLGFDQFFTLFHEVLFPGDSTWQFNPLTDPVIWILPETFFLHCFIIFLLIYETITIILLIIGRKHLKLRKYKNKMQAL
>NZ_CP007572.1|WP_000323544.1|990676_991447_+|TIGR01457-family-HAD-type-hydrolase
MAYKGYLIDLDGTIYKGKSRIPAGERFIERLQEKGIPYMLVTNNTTRTPESVQEMLRGFNVETPLETIYTATMATVDYMNDMNRGKTAYVIGEEGLKKAIADAGYVEDTKNPAYVVVGLDWNVTYDKLATATLAIQNGALFIGTNPDLNIPTERGLLPGAGSLNALLEAATRIKPVFIGKPNAIIMNKALEILNIPRNQAVMVGDNYLTDIMAGINNDIDTLLVTTGFTTVEEVPDLPIQPSYVLASLDEWTFNEG
>NZ_CP007572.1|WP_000523795.1|989938_990676_+|acyl-ACP-thioesterase
MGLLYRETYEVPFYESDTNHYMKLPQLLALALQISAKQSLKLGIGDDIVFKRYGLVWVVTDYIIDIERLPKHAEKIVIETEAKAHNKLLCYRYFYIYGEDGQKIITISSAFVLMDFKTRKIHPVLDDITSIYQSQRIKKVIRGPKYHPIGDSKVKQYHVRYFDLDMNGHVNNSKYLEWMYDVLDLDFLSSHIPKKIDLKYIKEIQYGTDIKSHWYQDGLVTRHDIIGGDAIHAQARIEWQEKKED
>NZ_CP007572.1|WP_000914659.1|988804_989935_+|oxygen-independent-coproporphyrinogen-III-oxidase
MLKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLQALIREFRSYDITELRTLYIGGGTPTSISAVQLDYLLTELIRDLNLNTLEEFTIEANPGDLTVDKIEVLQKSAVNRVSLGVQTFNDKHLKRIGRSHNEAQIYSTIDALKTAGFQNISIDLIYALPGQTMDDVRSNVAKALSLNIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEMFEYIISEMERNGFEHYEISNFTKPGFESRHNLMYWENVEYYGVGAGASGYLDGIRYRNRGPIQHYLKGVSEGNARLSEEVLSKNEMMEEELFLGLRKKEGVSIGKFEQKFGTSFEKRYGQIVQELQSDGLLKENNGFIQMTKKGLFLGDTVAEKFIVE
>NZ_CP007572.1|WP_041326298.1|987162_988608_-|IS1182-family-transposase
MFHKENPEYNRRQVGFYTLDELVPKDHFLRKVEETIDFSFIYDLVEDSYSSDNGRPSLDPVLLVKIPLIQCFYGIRSMRQTIKDIEVNTAYRWFLGLSLDDKVPHFTTYGKNYSRRFENKEVLAHIFSHVLHHVLEAGLIDPSEIFIDGTHIKAAANNHKYKNVVIDQKAKFMSEQLETEINLDRRKHAKKFLKPAKKGEAKPKKQSTTDPDSGWFHKGEHKEVFAYNAQVACDKHGWALAYTVESGNTHDSQAFPALFAKLEPFSPEFIIADSGYKTPSIAKFLLEKGITPVFPYTRPRGKKDFLHPKDFVYDEHFDCYLCPENQVLTYRTTTREGYREYKSNPKICKTCPLLAICTESRQYQKVVVRHIWKDALEVCEDIRHQSDMKELYQHRKETIERLFGTAKEYHNLRYTREKGKSKMEAKVGLTLACLNIKKLVKMMTGKTCYFTQISQYYWFMGEFGKNIKKTNIKNDVCLHSE
>NZ_CP007572.1|WP_001241816.1|986771_987152_+|hypothetical-protein
MRLWHQDIIELLPRQQLLGQHRECCALRGNGWGRKHETVDYVFRYSPYRLFAYHQLVMEEMMERGYRVSKEWLIAEYRGMKCPRYDTLNPVDLETPIYPEHNQDYLQECLWNLKAKGIDLPINKIK
>NZ_CP007572.1|WP_000438313.1|999316_999733_+|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVKRGFIGEVISRIERRGFSIDRLEVRHADADILKRHYAELTDRPFFPTLVDYMTSGPVIIGVISGEEVISTWRTMMGSTNPKDALPGTIRGDFAQAPSPNQATCNIVHGSDSPESATREIAIWFNN
>NZ_CP007572.1|WP_001019128.1|999868_1001701_+|elongation-factor-4
MNIEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRAEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGEVDAPLQALIFDSVYDAYRGVILQVRIINGMVKPGDKIQMMSNGKTFDVTEVGIFNPKAVGRDFLATGDVGYIAASIKTVADTRVGDTITLANNPAIEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSEFPDPTRVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDDKK
>NZ_CP007572.1|WP_000678289.1|1001946_1004580_+|pneumococcal-type-histidine-triad-protein
MKGQKIIALAGLVLSCHFALTACHTQEHKNSHHIKTKQVAKKKANKKKVSVKESHKKRKGVAGVDFPTDDGFLLTKDSKILSHTDSGIVVAHGNHSHFIFYSDLKGSKFSYLIPNANAKTNKNQAVRNFKAGAVAVNTLNDGYVFNPADIVSEDANGYVVRHGDHFHYIPKASLSQQKQVQASRAVSRLGNQSNSHYRVNSSKIAGLHHPTSDGFLFNGQGIKGTTPTGILVEHHSHLHFISFADLRKGGWGSIADRYQPQKKVDSKKQSPSSKKPRNENTLPKDIKDKLAYLARELHLDISRIRVLKTLNGEIGFEYPHDDHTHVIMAKDIDLSKPIPNPHHDDEDHHKGHHHDESDHKHEEHEHTKSNKLSDEDQKKLIYLAEKLGLNPNQIEVLTSEDGSIIFKYPHDDHSHTIASKDIEIGKPIPDGHHDHSHAKDKVGMATLKQIGFDDEIIQDILHADAPTPFPSNETNPEKMRQWLATVTKINIGQRTNPFQRFGLSLMPNIEVLGIGFTPINDMTPVLQFKKLKQLWMTNTGITDYSFLDKMPLLEGLDISQNGIKDLSFLTKYKQLSLIAAANNGITSLKPLAELPNLQFLVLSHNNISDLTPLSNLTKLQELHLDHNNVKNLSALSGKKDLKVLDLSNNNSADLSTLKTTSLETLLLNETNTSNLSFLKQNPKVSNLTINNAKLSSLDGIEESDEIVKVEAEGNQIKSLVLKNKQGSLKFLNVTNNQLTSLEGVNNYTSLETLSVSKNKLESLDIKTPNKTVTNLDFSHNNVPTSQLKLNEKNIPEAVAKNFPAVVEGSMVGNGSLAEKAAMASKEEKQVSDNTNHQKNTEKSAQANADSKKENPKTHDEHHDHEETDHAHVGHHHH
>NZ_CP007572.1|WP_000180011.1|1004679_1005339_+|HD-domain-containing-protein
MTMVKREDVILNATENMVYHKLKNDPSGHDWFHIVRVRNLAVELAHKEGANTFICQMVALLHDIIDDKICQDSKQASYELTQWLYSQDLTIAEVEHILDILENISFKAGTGLTMKTLEGQIVQDADRLDAMGAIGIARTMAYSGSKGRLIHDPNLKPRENLTLEEYRNGQDTAIMHFYEKLLKLKDLMNTKQGKMLAQKRHDFLELYLAEFYAEWNGKR
>NZ_CP007572.1|WP_000621143.1|1005347_1005812_+|GNAT-family-N-acetyltransferase
MIRRAKEKDLPDIAELLKQILMLHHEVRPDIFHTRGSKFSKEQLKEMLMDESRPIFVYESDEGKVVAHLFLQLQEKRDLPRKSFKTLYIDDLCIDEEVRGQQIGQKLIDFARQYAKKHGCYNITLNVWNDNQRAVSFYEKLGFKPQQTQMEEIL
>NZ_CP007572.1|WP_000665410.1|1005811_1006246_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MKETQEELRQRIGHTAYQVTQNSATEHAFTGKYDDFFEEGIYVDIVSGEVLFSSLDKFQSGCGWPAFSKPIENRMVTNHQDHSHGMHRIEVRSRQADSHLGHVFNDGPVDAGGLRYCINSAALDFIPYDQMAKRGYGDYLSLFD
>NZ_CP007572.1|WP_000168908.1|1006398_1009191_+|cation-transporting-P-type-ATPase
MASTNNVSDTNTRFAKEELEEVFEELGTTQGGLSDEEVAVRQKKYGLNLLSEVKQESIILLFLKNFTSLMAILLWVGGFVAIVSNSLELGLAIWMVNVINGIFSFIQEYRASQATQALKKMLPSYSRVLRKSSEEKILSEQLVPGDIVLIEEGDRISADGRLIKTTDLQVNQSALTGESNPIYKDSNVENDQSKTLIECDNMVFAGTTVSSGSATMVVTAIGMQTQFGQIADLTQGMKSEKSPLQRELDRLTKQISIISITVGIIFFLAATFFVKEPVSKSFIFALGMIVAFIPEGLLPTVTLSLAMAVQRMAKEHALVKKLSSVETLGATSVICSDKTGTLTQNEMTVNRLWQNGKSYQVTGLGYAPEGQILFEGDNICFGNSDRGDLEKLIRFAHLCSNAQVLPPNDDRSTYTVLGDPTEACLNVLLEKSGINRQENRKFAPRLKELPFDSVRKRMTTIHSLGGDEKDKKISITKGAPKEILNLSDYVLSDDKVIPLNKEERNKIQLANDTFAKDGLRVLAVSYCDIEGFSKEQWTQENLEQHMVFIGLIAMSDPPREGVREAIDKCHAASIRIIMVTGDYGLTALSIAKNIGIIRNDNAKVISGLELSEMTDSQLKKELSGEVVFARVAPEQKYRVVTILQEMGEVVAVTGDGVNDAPALKKSDIGVAMGVTGTDVAKESADMILTDDHFASIVHAVEEGRAVYQNIKKFLTYIFNSNTPEAVPSAFFLFSKGFIPLPLTVMQILAVDLGTDMLPALGLGVEPPETDVMNRPPRRLTDRLLDKGLLIKSFLWYGTIESVLAMGGFFWAHYLRYGNFTFFVANGIPYREATTMTLGAIIFSQIGMVMNSRTSYQSIRALSIFGNKLINFGIIMEILAFLVLVYVPPFHNLFNTASLGLSHWLYLISCPFIMIGLDEVRKLFSSRKNKR
>NZ_CP007572.1|WP_000065324.1|1009190_1010294_+|DUF2974-domain-containing-protein
MSNIITYLKNNSNLTFDELALNDVDILCLNEFGYISFEKLINTTEMKSVLVCELYHEYLQTMAKSYSFMFTSQRHDLCQLMMTSKRFKNLTLSYYRAEVSLEFEKQFAAMVFTIPNIDYHQVVFRGTDANLIGWKEDFKLTYMREISAHRSAIKYLNTILPYFDKVVLSGHSKGGNLALYAAMFTKPDLKAKIDLIWLIDSPGLQKTLLPTTEYKTTKQKCIRLLPEESIVGMMLYSDIEPLIISSNARGILQHDVTTWEIQEPAILKTGAGLSLKSICFEKTFQQWMAELKSQERKLFFDLLFDSFLSSGVSSLDDFNLASRAKMMKAFHSFRELDDDKKRLFNKSLKLLVTIFWGAYHDNSRKTK
>NZ_CP007572.1|WP_000146568.1|1010412_1011051_-|CatB-related-O-acetyltransferase
MASILKKHLEKRLELKNDPMRTDMSTGASYPKYGFSVGKYTYGYQQFFYEGVNLKEIGAFCSIAQNVTITGMNHPTDHITTNPFIYYKSRGFINEDRADLIDEKKNGKVIIGNDVWIGTNVTILPSVTIGNGAIIGAGSVITKDIPDYAVVAGKPAKIIKYRFSEEEITLLNASQWWNWSDEAIKEHISEFSDKKEFFNTLKSISENKNHKL
>NZ_CP007572.1|WP_001056394.1|1013298_1013910_+|TVP38/TMEM64-family-protein
MNMKLSKRYRFWQKVIKALGVLALIATLVLVVYLYKLGILNDSNELKDLVHKYEFWGPMIFIVAQIVQIVFPVIPGGVTTVAGFLIFGPTLGFIYNYIGIIIGSVILFWLVKFYGRKFVLLFMDQKTFDKYESKLETSGYEKFFIFCMASPISPADIMVMITGLSNMSIKRFVTIIMITKPISIIGYSYLWIYGGDILKNFLN

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Crispr_ID: NZ_CP007572_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007572_2

1141304-1141374

Orphan

Consensus_repeat	Method
CGTTGACGACGCTCTAGAACATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007572_2

>merge|NZ_CP007572|2|1141304-1141374|CRISPRCasFinder
CGTTGACGACGCTCTAGAACATTACCTTGGCTTCTGTTTTCTGCATCGCGTTGACGACGCTCTAAAACATT

>NZ_CP007572|2|2|1141304-1141374|CRISPRCasFinder
CGTTGACGACGCTCTAGAACATT	ACCTTGGCTTCTGTTTTCTGCATCG
CGTTGACGACGCTCTAAAACATT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007572.1\|WP_001016473.1\|1132311_1133235_-\|aspartate-carbamoyltransferase-catalytic-subunit	unknown	unknown	gnl\|CDD\|234849
NZ_CP007572.1\|WP_000890175.1\|1135345_1136047_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NZ_CP007572.1\|WP_000025410.1\|1137531_1139073_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NZ_CP007572.1\|WP_000219401.1\|1146707_1147586_-\|NAD-dependent-deacetylase	unknown	unknown	gnl\|CDD\|223915
NZ_CP007572.1\|WP_000845314.1\|1143902_1145573_-\|formate--tetrahydrofolate-ligase	unknown	unknown	gnl\|CDD\|237403
NZ_CP007572.1\|WP_000455156.1\|1150901_1151738_-\|lipoate--protein-ligase-family-protein	unknown	unknown	gnl\|CDD\|319740
NZ_CP007572.1\|WP_000826109.1\|1131221_1132298_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237139
NZ_CP007572.1\|WP_000638282.1\|1142188_1143784_-\|cardiolipin-synthase	unknown	unknown	gnl\|CDD\|197257
NZ_CP007572.1\|WP_000362328.1\|1134703_1135333_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771
NZ_CP007572.1\|WP_001067079.1\|1149709_1150909_-\|NADH-dependent-flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240086
NZ_CP007572.1\|WP_001165747.1\|1139203_1139542_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236436
NZ_CP007572.1\|WP_000778223.1\|1148726_1149713_-\|MsnO8-family-LLM-class-oxidoreductase	unknown	unknown	gnl\|CDD\|274646
NZ_CP007572.1\|WP_001133614.1\|1147554_1148373_-\|protein-ADP-ribose-hydrolase	unknown	unknown	gnl\|CDD\|235225
NZ_CP007572.1\|WP_000542443.1\|1139711_1140788_-\|aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|237845
NZ_CP007572.1\|WP_000280832.1\|1145661_1146681_-\|lipoate--protein-ligase	unknown	unknown	gnl\|CDD\|223173
NZ_CP007572.1\|WP_000717327.1\|1148365_1148698_-\|glycine-cleavage-system-protein-H	unknown	unknown	gnl\|CDD\|223583
NZ_CP007572.1\|WP_000282561.1\|1151876_1152578_+\|phosphopantothenate--cysteine-ligase	unknown	unknown	gnl\|CDD\|235856
NZ_CP007572.1\|WP_001178653.1\|1136259_1137492_-\|threonine/serine-exporter-family-protein	unknown	unknown	gnl\|CDD\|377697
NZ_CP007572.1\|WP_000275479.1\|1133399_1134692_-\|dihydroorotase	unknown	unknown	gnl\|CDD\|236479
NZ_CP007572.1\|WP_001126465.1\|1128008_1131191_-\|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|235393

Protein	Function_ID	Function_description	E-value
NZ_CP007572.1\|WP_001016473.1\|1132311_1133235_-\|aspartate-carbamoyltransferase-catalytic-subunit	gnl\|CDD\|234849	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit.	1.53654e-159
NZ_CP007572.1\|WP_000890175.1\|1135345_1136047_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	2.09775e-129
NZ_CP007572.1\|WP_000025410.1\|1137531_1139073_-\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NZ_CP007572.1\|WP_000219401.1\|1146707_1147586_-\|NAD-dependent-deacetylase	gnl\|CDD\|223915	COG0846, SIR2, NAD-dependent protein deacetylases, SIR2 family [Transcription].	5.11635e-59
NZ_CP007572.1\|WP_000845314.1\|1143902_1145573_-\|formate--tetrahydrofolate-ligase	gnl\|CDD\|237403	PRK13505, PRK13505, formate--tetrahydrofolate ligase; Provisional.	0
NZ_CP007572.1\|WP_000455156.1\|1150901_1151738_-\|lipoate--protein-ligase-family-protein	gnl\|CDD\|319740	cd16435, BPL_LplA_LipB, biotin-lipoate ligase family. This family includes biotin protein ligase (BPL), lipoate-protein ligase A (LplA) and octanoyl-[acyl carrier protein]-protein acyltransferase (LipB). Biotin is covalently attached at the active site of certain enzymes that transfer carbon dioxide from bicarbonate to organic acids to form cellular metabolites. Biotin protein ligase (BPL) is the enzyme responsible for attaching biotin to a specific lysine at the active site of biotin enzymes. Biotin attachment is a two step reaction that results in the formation of an amide linkage between the carboxyl group of biotin and the epsilon-amino group of the modified lysine. Lipoate-protein ligase A (LplA) catalyses the formation of an amide linkage between lipoic acid and a specific lysine residue in lipoate dependent enzymes.	4.20812e-71
NZ_CP007572.1\|WP_000826109.1\|1131221_1132298_-\|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
NZ_CP007572.1\|WP_000638282.1\|1142188_1143784_-\|cardiolipin-synthase	gnl\|CDD\|197257	cd09160, PLDc_SMU_988_like_2, Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins. Putative catalytic domain, repeat 2, of Streptococcus mutans uncharacterized protein SMU_988 and similar proteins. Although SMU_988 and similar proteins have not been functionally characterized, members in this subfamily show high sequence homology to bacterial cardiolipin (CL) synthases, which catalyze the reversible phosphatidyl group transfer between two phosphatidylglycerol molecules to form CL and glycerol. Members of this subfamily contain two HKD motifs (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the phospholipase D (PLD) superfamily. The two motifs may be part of the active site and may be involved in phosphatidyl group transfer.	3.30901e-99
NZ_CP007572.1\|WP_000362328.1\|1134703_1135333_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	1.94914e-76
NZ_CP007572.1\|WP_001067079.1\|1149709_1150909_-\|NADH-dependent-flavin-oxidoreductase	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	2.99926e-179
NZ_CP007572.1\|WP_001165747.1\|1139203_1139542_-\|hypothetical-protein	gnl\|CDD\|236436	PRK09263, PRK09263, anaerobic ribonucleoside triphosphate reductase; Provisional.	7.78178e-24
NZ_CP007572.1\|WP_000778223.1\|1148726_1149713_-\|MsnO8-family-LLM-class-oxidoreductase	gnl\|CDD\|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	5.85304e-113
NZ_CP007572.1\|WP_001133614.1\|1147554_1148373_-\|protein-ADP-ribose-hydrolase	gnl\|CDD\|235225	PRK04143, PRK04143, protein-ADP-ribose hydrolase.	2.87502e-149
NZ_CP007572.1\|WP_000542443.1\|1139711_1140788_-\|aspartate-semialdehyde-dehydrogenase	gnl\|CDD\|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
NZ_CP007572.1\|WP_000280832.1\|1145661_1146681_-\|lipoate--protein-ligase	gnl\|CDD\|223173	COG0095, LplA, Lipoate-protein ligase A [Coenzyme metabolism].	1.25622e-82
NZ_CP007572.1\|WP_000717327.1\|1148365_1148698_-\|glycine-cleavage-system-protein-H	gnl\|CDD\|223583	COG0509, GcvH, Glycine cleavage system H protein (lipoate-binding) [Amino acid transport and metabolism].	7.35002e-28
NZ_CP007572.1\|WP_000282561.1\|1151876_1152578_+\|phosphopantothenate--cysteine-ligase	gnl\|CDD\|235856	PRK06732, PRK06732, phosphopantothenate--cysteine ligase; Validated.	6.93696e-140
NZ_CP007572.1\|WP_001178653.1\|1136259_1137492_-\|threonine/serine-exporter-family-protein	gnl\|CDD\|377697	pfam06738, ThrE, Putative threonine/serine exporter. ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.	1.03064e-52
NZ_CP007572.1\|WP_000275479.1\|1133399_1134692_-\|dihydroorotase	gnl\|CDD\|236479	PRK09357, pyrC, dihydroorotase; Validated.	0
NZ_CP007572.1\|WP_001126465.1\|1128008_1131191_-\|carbamoyl-phosphate-synthase-large-subunit	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0

>NZ_CP007572.1|WP_000542443.1|1139711_1140788_-|aspartate-semialdehyde-dehydrogenase
MGYTVAIVGATGAVGTQMIRQLEQSKLPIEQVKLLSSSRSAGKILHFKDEAIRVEETTKESFYDVDIALFSAGGSISAKFAPYAVKSGAVVVDNTSYFRQNPDVPLVVPEVNAHAMIGHNGIIACPNCSTIQMMIALEPIRQKWGIERVIVSTYQAVSGSGARAVEETKEQLRQVLNDNLSPDQLIATVLPCSSDQKHYPIAFNALPQIDIFTDNDYTYEEMKMTLETKKIMEDATIKVSATCVRIPVLSGHSESIYIETKELASISEIKKAIANFPGAVLQDLPSQQIYPQAINAVGHRETFVGRIRKDLDQENGVHMWVVSDNLLKGAAWNSVQIAETLHKNGLVKPAKELKFELI
>NZ_CP007572.1|WP_001165747.1|1139203_1139542_-|hypothetical-protein
MQIIKRDGQIVEFDPEKIYQAILKAAQTVYVLDESLRQDLAQVTKKVILDLEDAQVERPTINMIQSLVENRLLDAGYIHTAEHYISYRLQRDLERNGYDDQITVHLHFEKIK
>NZ_CP007572.1|WP_000025410.1|1137531_1139073_-|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MSILEVKNLSHGFGDRAIFENVSFRLLKGEHIGLIGANGEGKSTFMSIVTGHLQPDEGKIEWSKYVTAGYLDQHTVLEEGQTVRDVLRTAFDELFKTEARINDIYISMADDGADVDSLMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDSDVTELSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDIPFLNDVINIVYHVENQDLVRYSGDYTNFESVYAMKKAQLEAAYERQQKEIADLQDFVNRNKARVATRNMAMSRQKKLDKMDIIELQAEKPKPSFEFKESRTPGRFIFQAKDLQIGYDRALTKPLNLTFERNQKIAIVGANGIGKTTLLKSLLGIIPPISGNVERGDFIDLGYFEQEVPGGNRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQVLSGGEQSKVRFCLLMNRENNVLVLDEPTNHLDVDAKDELKRALKAYKGSILMVCHEPDFYEGWMDDVWDFNQLS
>NZ_CP007572.1|WP_001178653.1|1136259_1137492_-|threonine/serine-exporter-family-protein
MQNDMSVVLRAGKLLIESGAEVYRVEDTMKHFAKALQIENFEAYVVSSSIIASGINRYGKQEAKVCNTDGVTANLGRLEAVNNLSRQIAKQDLVSPEEIVKQLDLIEHQKDYSLLVTLISYFCGAGSFSLALGSSLLDSFSAAVTGLILGYFLNLMESRIHTGFLLTILGSSVVALSANLLYFSGLGEHRSIIILGALMVMVPGAAFVNSVREFSQNNFSTGLALIMSALLICISISAGVAITIEIIPFAEQMIGSFSGVPNTILEIIIRTLMAGLGTIAFSILYHVPKRYFLDLGILGAISWMLYLILWQQFHMDAIAVFFPGLFITYFSRLLAAKRKCPATVFLATSMFPLIPGLSFYRAVYFLLTGADAVAMEYFRSCFVTAFTIAIAISIVQQIPLSFFIRRKMIK
>NZ_CP007572.1|WP_000890175.1|1135345_1136047_-|orotidine-5'-phosphate-decarboxylase
MLEKCPIIALDFSDLASVTTFLEHFPKEELLFVKIGMELYYSEGPSIIRYIKSLGHRIFLDLKLHDIPNTVRSSMSVLAKLGIDMTNVHAAGGVEMMKAAREGLGEGPILLAVTQLTSTSQEQMQVDQHINLSVVDSVCHYAQKAQEAGLDGVVASAQEVKQIKKQTNEHFICLTPGIRPPQTNQLDDQKRTMTPEQARIVGADYIVVGRPITKAENPYQAYLEIKEEWNRIK
>NZ_CP007572.1|WP_000362328.1|1134703_1135333_-|orotate-phosphoribosyltransferase
MDLARQIAMELLDIQAVYLRPQQPFTWASGVKSPIYTDNRVTLSYPETRTLIENGFVKQIQKHFPNVDIIAGTATAGIPHGAIIADKMNLPFAYIRSKAKDHGVGNQIEGRVYSGQKMVIIEDLISTGGSVLEAVTAAQSQGIEVLGVVAIFTYQLAKAEQAFREADIPLVTLTDYNQLIKVAKVNGYITADQLVLLKKFKEDQMNWQS
>NZ_CP007572.1|WP_000275479.1|1133399_1134692_-|dihydroorotase
MYIIKNGLIIDPQSGFNQVSDMLIDQGKIKQISKEIDIKGIPIIDASNKIVAPGLVDIHVHFREPGQTHKENIHTGALSAAVGGFTTVLMMANTNPTISSPEIVKQVKESAAKEAIKIETVATITKSLNGKDLVNFEELLEAGVAGFSDDGIPLTDTKVLQEAMNLARKHDVVLSLHEEDPSLNGVLGINEHIAQKIYHVCGASGLAEYSMIARDAMIAYQTQAKVHIQHLSSSESVEVVDFAQKLGANLTAEVTPQHFSKTENLLLTKGANAKLNPPLRLEKDRQALIDGLKSGVISIIASDHAPHHIMEKAADNISQAPSGMTGLETSLALGITYLVSTKELSMIDFLAKMTCNPAQLYGFDAGYLREGGPADIVIFDQAEERIIKAEFASKSSNSPFIGDKLKGVIHYTICNGEIVYQKDSHAATLV
>NZ_CP007572.1|WP_001016473.1|1132311_1133235_-|aspartate-carbamoyltransferase-catalytic-subunit
MNHQTQTLSLEHFVSLEELSNQEVMSLIKRSIEVKENPSNIGFDKDYYVSNLFFENSTRTHKSFEMAELKLGLKTIEFNADTSSVNKGETLYDTILTMSALGLDVCVIRHPDIDYYKELIASPNIHSAIVNGGDGSGQHPSQSLLDLVTIYEEFGYFKGLKIAIVGDLTHSRVAKSNMQVLKRLGAEIFFSGPKEWYSSQFDEYGQYLPIDQLVDQIDVLMLLRVQHERHDGKGVFSKESYHQQFGLTKERYKHLRDTAIIMHPAPVNRDVEIASDLVEADKARIVKQMSNGVYARIAILEAVLNSR
>NZ_CP007572.1|WP_000826109.1|1131221_1132298_-|glutamine-hydrolyzing-carbamoyl-phosphate-synthase-small-subunit
MKRLLLLEDGSVFEGEAFGADVETSGEIVFSTGMTGYQESITDQSYNGQIITFTYPLIGNYGINRDDYESIRPTCKGVVIYEWAEYPSNWRQQMTLDEFLKLKGIPGISGIDTRALTKIIRKHGTMKACLINEGNSIHEALENLQKSVLLNDQIEQVSTKLAYASPGVGKNIVLVDFGLKHSILRELSQRQCHITVVPHTTTAQEILNLNPDGVLLSNGPGNPEQLPNALQMIQEIQGKIPIFGICMGHQLFAKANGAKTYKMTFGHRGFNHAVRHLQTGQVDFTSQNHGYAVSREDFPEALFITHEEINDKTVEGVRHKYYPAFSVQFHPDAAPGPHDTSYLFDEFINMIDDFQQKS
>NZ_CP007572.1|WP_001126465.1|1128008_1131191_-|carbamoyl-phosphate-synthase-large-subunit
MPKRTDIRKIMVIGSGPIVIGQAAEFDYSGTQACLSLKEEGYQVVLVNSNPATIMTDKDIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMALSKNGILEELNVELLGTKLSAIDKAEDRDLFKQLMEELNQPIPESEIVNSVEEAIQFAEQIGYPLIVRPAFTLGGTGGGMCDNQEQLVDITTKGLKLSPVTQCLIERSIAGFKEIEYEVMRDAADNALVVCNMENFDPVGIHTGDSIVFAPAQTLSDVENQLLRDASLDIIRALKIEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEVINPITKTTYAMFEPALDYVVAKMPRFPFDKFESGDRKLGTQMKATGEVMAIGRNIEESLLKACRSLEIGVDHIKIADLDNVSDDVLLEKIRKAEDDRLFYLAEALRRHYSIEKLASLTSIDSFFLDKLRVIVELEDLLSKNRLDINILKKVKNKGFSDKAIASLWQINEDQVRNMRKEAGILPVYKMVDTCASEFDSATPYFYSTYAVENESLISDKASILVLGSGPIRIGQGVEFDYATVHSVKAIRESGFEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIDLEKPEGVILQFGGQTAINLAKDLNKAGVKILGTQLEDLDRAENRKQFEATLQALNIPQPPGFTATTEEEAVNAAQKIGYPVLVRPSYVLGGRAMKIVENEEDLRHYMTTAVKASPDHPVLIDAYLIGKECEVDAISDGQNILIPGIMEHIERAGVHSGDSMAVYPPQTLSETIIETIVDYTKRLAIGLNCIGMMNIQFVIKDQKVYVIEVNPRASRTLPFLSKVTHIPMAQVATKVILGDKLCNFTYGYDLYPASDMVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSDINLQKALYKAFEAAYLHMPDYGNIVFTVDDTDKEEALELAKVYQSIGYRIYATQGTAIYFDANGLETVLVGKLGENDRNHIPDLIKNGKIQAVINTVGQNNIDNHDALIIRRSAIEQGVPLFTSLDTAHAMFKVLESRAFTLKVLD
>NZ_CP007572.1|WP_000638282.1|1142188_1143784_-|cardiolipin-synthase
MIWRGEKLISNKVKIVRLLNKSKKSLLRGIFSRTTVIAILLILQLLFLLASYSWLEQYRVWLATVEHILTIGAVLYLVNSEMDALSRVTWLILVMIAPLLGAMFLMYTKFDWGYRGLKQRLETLIDESQIYLEDDPETLNQLKSSTSTTYHLVQYFEKAHGNFPVYRNTDVTFLPTGEAFFEKMKEELLKAKKYIFLEFFIIDEGIMWGEILSILEQKVEEGVEVRILYDGMIEITKLSFDYTKRLEKIGIKAKAFSPISPFISTYYNYRDHRKIVVIDGVVGMTGGVNLADEYINHIELFGHWKDSGIMLKGKAVDSFLLLFLQMWSITEEKMLVAPYLGVHDDLVENEGYVIPYGDSPLDTDKVGENVYIDILNHAREYVYIMTPYLILDSELEHAIQFAAERGVDVRIIMPGIPDKPIPYALAKTYYQALTKSGVKIYEYTPGFVHSKIFLSDNTKAVVGTINLDYRSLYHHFECAVYLYKVDAIQDIYRDYMDTLNKSRLVSLKDINNIPKFQKVIGIVTKTIAPLL
>NZ_CP007572.1|WP_000845314.1|1143902_1145573_-|formate--tetrahydrofolate-ligase
MKTDIEIAQSVALKPIAEIVEQVGIGFDDIELYGKYKAKLSFDKIEAVRSQKVGKLILVTAINPTPAGEGKSTMSIGLADALNKIGKKTMIALREPSLGPVMGIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELDIDQRRVIWKRVVDLNDRALRQVIVGLGSPVNGIPREDGFDITVASEIMAILCLATDLSDLKKRLSNIVVAYSRDRKPIYVKDLKIEGALTLILKDAIKPNLVQTIYGTPALVHGGPFANIAHGCNSVLATSTALRLADYVVTEAGFGADLGAEKFLDIKTPNLPTSPDAIVIVATLRALKMHGGVSKEDLSQENVKAVKRGFTNLERHVNNMRQYGVPVVVAINQFTADTESEIATLKTLCSNIDVAVELASVWEDGADGGLELAQTVANVIETQSSNYKRLYNDEDTIEEKIKKIVTKIYGGNKVHFGPKAQIQLKEFSDNGWDKMPICMAKTQYSFSDNPNLLGAPTDFDITVREFVPKTGAGFIVALTGDVLTMPGLPKKPAALNMDVLEDGTAIGLF
>NZ_CP007572.1|WP_000280832.1|1145661_1146681_-|lipoate--protein-ligase
MYLIEPIRNGKRITDGAIALAMQVYILQNVFLDDDILFPYYCDPKVEIGKFQNAVIETNQEYLKEHDIPVVRRDTGGGAVYVDSGAVNICYLMKDHGQFGDFKRAYEPAIKALKTLGASSVEMRGRNDLVIDGKKVSGAAMTIVNGRIYGGYSLLLDVDFDAMEKVLNPNRKKIESKGIKSVRSRVGDIRSHLSEDYRHITTDQFKDLMVCQLLHIDHIDQAKRYHLTEKDWAAIDALADEKYKNWDWNYGNSPQYSYHRDARFPSGTYDFHLEIEKGIITNCRIYGDFFSSKDISDIENLLIGCPMKEELVLEKLSTVSLEDYFGQTSPEEIKAVLFP
>NZ_CP007572.1|WP_000219401.1|1146707_1147586_-|NAD-dependent-deacetylase
MTVWKTLEKTNHSQSEILSQLIEESDAIVVGIGAGMSAADGFTYIGPRFEEAFPDFIAKYQLLDMLQASLYDFEDWEEYWAFQSRFVALNYLDQPVGQAYLDLKDILAKKEYHIITTNADNAFAVADYNLEKVFHIQGEYGLWQCSQHCHQQTYRNDQAIRQMIAQQKDMKIPSNLIPKCPKCDQPFEINKRNEEKGMVEDADFHAQRQRYENFLSQHQNDKVLYLEIGVGHTTPQFIKHPFWRFVSLNENSLFVTLNHKHYRIPQKIRSRSVQLTQHIAELIAEAKKEIIG
>NZ_CP007572.1|WP_001133614.1|1147554_1148373_-|protein-ADP-ribose-hydrolase
MPNQKQLLLAMIEYLRSEKSTDVDDLRTTDLQTVWRALVNQQDPQNISQEYLSLEDRYLSHWWNTQKVKTIDVCHQTVYSNVFTYHGDICLLQVDAIVNAANGKLLGCFIPNHHCIDNHIHTFAGSRLRLACHQLMTQQGRMEAVGQAKLTESYHLPCKYVIHTVGPYVKVDQKPSRIREDLLKSSYKSCLQLAVRANLKTIVFPCISTGEFGFPNQRAAELAVQAILEWQRENQHKLYIIFNTFTPKDQEIYQKLLLKEEIDDSMEDSRKN
>NZ_CP007572.1|WP_000717327.1|1148365_1148698_-|glycine-cleavage-system-protein-H
MKKIANYLLIEKNEERYTISLTPELQDDLGTVGYVEFTDDTNLEVDDVILNIEASKTVMAILSPLTGKVVKVNTAASQEPTLLNSEKADENWLVVLTDVDYAAFEALENA
>NZ_CP007572.1|WP_000778223.1|1148726_1149713_-|MsnO8-family-LLM-class-oxidoreductase
MKLSVLDYGLIDYGKTASDAIQETILLSQEAERLGYHQFWVAEHHGVKAFSISNPELMIMHLANQTKSIKIGSGGIMPLHYSSFKLAETLKTLETCHPNRVSIGLGNSLGTVKVSNALRSLHKAHDYEEVLEELKSWLIDESSSKEPLVQPTLSSFPDLYVLGSGQKSAYLAAKLGLGFTFGVFPFMDKDPLTEAKKLSSLYYHQFEEYYPNKSPNLMVAAFVVIADTSEEAENIAKTLDIWMLGNKDFNEFATFPTIEEANHYQLTPEQKAKIKSNRHRMIVGDPKQVKDSLDALVNASQAEELLLIPLVPGLDQRIKSLKLLSQLY
>NZ_CP007572.1|WP_001067079.1|1149709_1150909_-|NADH-dependent-flavin-oxidoreductase
MNNVQGNLFRPLILPNGLSLENRFVLSPMVTNSSTSEGFVTDDDIAYAVRRAKSAPLQITGAAYVTEYGQLFEYGFSVSKDEDIPGLTKLAKAMKSKGAKAVLQLTHAGRFSSHTLARHGYVYGPSPMQLQSPYPHQVKELTHKDILMIIDEYVQATRRAIQAGFDGVEISSAQRLLIQTFFSTFSNQRKDEYGPQTLTNRCRLGLEVFKAVQKVIREEAESDFILGFRATPEETRGSQIGYSIEEFMEFLEKILAIAQVDYLAIASWGHDVFRNTIRSEGVYKGQLVNQVIFEHFGDRVPIMATGGINSASKVFEALQHAHMVGASTPLVVDPEFLQKIKAKRSDQINLRIKVSDLEGLAIPKASFKDIVPLMDYGESLPKEAREVFRELRSNYREER
>NZ_CP007572.1|WP_000455156.1|1150901_1151738_-|lipoate--protein-ligase-family-protein
MEWQDLAQLPVSIFKDYVTDAQDAEKPFIWTEVFLREINRSNQEIILHIWPMTKTVILGMLDRELPHLELAKKEIISRGYEPVVRNFGGLAVVADEGILNFSLIIPDVFERKLSISDGYLIMVDFIRSIFSDFYQPIEHFEVETSYCPGKFDLSINGKKFAGLAQRRIKNGIAVSIYLSVCGDQKERSRMISDFYKIGLGDTGSPIAYPNVDPEIMANLSDLLDCPMTVEDVIDRMLISLKQVGFNDRLLMIRPDLVAEFDRFQAKSMANKGTVSRDE
>NZ_CP007572.1|WP_000282561.1|1151876_1152578_+|phosphopantothenate--cysteine-ligase
MYNMAMKILITSGGTTEKIDTVRSITNHATGALGKIIAEKYLREGHQVTLVTTKNAIKPESATNLSIFEIEDVDSLIKTLKPLVKEHDILIHSMAVSDYTPVYMADFEKVKSSDDLDTFLRKDNHEGKISSESEYQVLFLKKTPKVISLVKKWNPQIILVGFKLLVNVTKENLFKVARHSLIKNKATFILANDLIDITSKHHIAYLLDHDNVYKATTKEDIAQLIYEKVKKYD

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Crispr_ID: NZ_CP007572_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007572_3

2078857-2079330

Orphan

Consensus_repeat	Method
TCTGGTTTNGCCTCTGGN	CRT

9 spacers

The CRISPR arrays of NZ_CP007572_3

>merge|NZ_CP007572|3|2078857-2079330|CRT
TCTGGTTTAGCCTCTGGCTTAACGTCTGGTTTAACTTCTGGCTTAGCCTCTGGTTTGGCCTCTGGCTTAACGTCTGGTTTAACTTCTGGTTTGGCCTCTGGCTTAACGTCTGGTTTAACTTCTGGCTTAGCCTCTGGTCTGGCCTCTGGCTTAACGTCTGGTTTAATTTCTGGTTTAGCCTCTGGTTTAACTTCTGGCTTAACGTCTGGTTTAACTTCTGGCTTAGCCTCTGGTCTGGCCTCTGGCTTAACGTCTGGTTTGGCTTCTGGCTTAACGTCTGGTTTGGCCTCTGGCTTAACGTCTGGTTTAACTTCTGGCTTAGCCTCTGGTTTGGCTTCTGGTTTGGCCTCTGGTTTGGCTTCTGGTTTGGCCTCTGGTTTGGCTTCTGGCTTAGCTTCTGGCTTAACGTCTGGCTTAACATCTGGTTTGGCTTCTGGTTTAACTTCTGGCTTAGCTTCTGGTTTGGCTACTTTT

>NZ_CP007572|3|2|2078857-2079330|CRT
TCTGGTTTAGCCTCTGGC	TTAACGTCTGGTTTAACT
TCTGGCTTAGCCTCTGGT	TTGGCCTCTGGCTTAACGTCTGGTTTAACTTCTGGTTTGGCCTCTGGCTTAACGTCTGGTTTAACT
TCTGGCTTAGCCTCTGGT	CTGGCCTCTGGCTTAACGTCTGGTTTAATT
TCTGGTTTAGCCTCTGGT	TTAACTTCTGGCTTAACGTCTGGTTTAACTTCTGGCTTAGCC
TCTGGTCTGGCCTCTGGC	TTAACGTCTGGTTTGGCTTCTGGCTTAACG
TCTGGTTTGGCCTCTGGC	TTAACGTCTGGTTTAACTTCTGGCTTAGCCTCTGGTTTGGCT
TCTGGTTTGGCCTCTGGT	TTGGCTTCTGGTTTGGCC
TCTGGTTTGGCTTCTGGC	TTAGCTTCTGGCTTAACGTCTGGCTTAACA
TCTGGTTTGGCTTCTGGT	TTAACTTCTGGCTTAGCT
TCTGGTTTGGCTACTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007572.1\|WP_000161343.1\|2068576_2069263_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NZ_CP007572.1\|WP_000057521.1\|2081644_2081797_-\|50S-ribosomal-protein-L33	unknown	unknown	gnl\|CDD\|234783
NZ_CP007572.1\|WP_000564842.1\|2074110_2075244_-\|ISAs1-like-element-IS1548-family-transposase	unknown	unknown	gnl\|CDD\|227720
NZ_CP007572.1\|WP_000953631.1\|2076932_2077778_-\|patatin-family-protein	unknown	unknown	gnl\|CDD\|132847
NZ_CP007572.1\|WP_041326819.1\|2085048_2086551_-\|IS1182-family-transposase	unknown	unknown	gnl\|CDD\|226192
NZ_CP007572.1\|WP_041326822.1\|2088496_2089708_-\|phosphopentomutase	unknown	unknown	gnl\|CDD\|235430
NZ_CP007572.1\|WP_000887149.1\|2077915_2078455_-\|transcription-termination/antitermination-protein-NusG	unknown	unknown	gnl\|CDD\|180161
NZ_CP007572.1\|WP_000074728.1\|2075642_2076890_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340929
NZ_CP007572.1\|WP_001159688.1\|2090475_2091678_-\|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl\|CDD\|224883
NZ_CP007572.1\|WP_000764814.1\|2081845_2084167_-\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|223815
NZ_CP007572.1\|WP_000497678.1\|2081435_2081609_-\|preprotein-translocase-subunit-SecE	unknown	unknown	gnl\|CDD\|223762
NZ_CP007572.1\|WP_000410681.1\|2062613_2063306_-\|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224215
NZ_CP007572.1\|WP_000903269.1\|2070740_2071349_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007572.1\|WP_000730413.1\|2069259_2070648_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NZ_CP007572.1\|WP_001182060.1\|2091698_2092478_-\|uridine-phosphorylase	unknown	unknown	gnl\|CDD\|350167
NZ_CP007572.1\|WP_000610953.1\|2062300_2062624_-\|AzlD-domain-containing-protein	unknown	unknown	gnl\|CDD\|226827
NZ_CP007572.1\|WP_000459243.1\|2086686_2088327_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226987
NZ_CP007572.1\|WP_000010479.1\|2084210_2085095_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP007572.1\|WP_000145175.1\|2071438_2073940_-\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NZ_CP007572.1\|WP_000453156.1\|2089774_2090446_-\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234784

Protein	Function_ID	Function_description	E-value
NZ_CP007572.1\|WP_000161343.1\|2068576_2069263_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	8.44527e-63
NZ_CP007572.1\|WP_000057521.1\|2081644_2081797_-\|50S-ribosomal-protein-L33	gnl\|CDD\|234783	PRK00504, rpmG, 50S ribosomal protein L33; Validated.	2.53308e-18
NZ_CP007572.1\|WP_000564842.1\|2074110_2075244_-\|ISAs1-like-element-IS1548-family-transposase	gnl\|CDD\|227720	COG5433, COG5433, Transposase [DNA replication, recombination, and repair].	7.2354e-31
NZ_CP007572.1\|WP_000953631.1\|2076932_2077778_-\|patatin-family-protein	gnl\|CDD\|132847	cd07208, Pat_hypo_Ecoli_yjju_like, Hypothetical patatin similar to yjju protein of Escherichia coli. Patatin-like phospholipase similar to yjju protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins, and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	5.13221e-122
NZ_CP007572.1\|WP_041326819.1\|2085048_2086551_-\|IS1182-family-transposase	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.03294e-27
NZ_CP007572.1\|WP_041326822.1\|2088496_2089708_-\|phosphopentomutase	gnl\|CDD\|235430	PRK05362, PRK05362, phosphopentomutase; Provisional.	0
NZ_CP007572.1\|WP_000887149.1\|2077915_2078455_-\|transcription-termination/antitermination-protein-NusG	gnl\|CDD\|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	3.00072e-83
NZ_CP007572.1\|WP_000074728.1\|2075642_2076890_+\|MFS-transporter	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.78212e-69
NZ_CP007572.1\|WP_001159688.1\|2090475_2091678_-\|NupC/NupG-family-nucleoside-CNT-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	3.49248e-155
NZ_CP007572.1\|WP_000764814.1\|2081845_2084167_-\|penicillin-binding-protein	gnl\|CDD\|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	0
NZ_CP007572.1\|WP_000497678.1\|2081435_2081609_-\|preprotein-translocase-subunit-SecE	gnl\|CDD\|223762	COG0690, SecE, Preprotein translocase subunit SecE [Intracellular trafficking and secretion].	5.81702e-09
NZ_CP007572.1\|WP_000410681.1\|2062613_2063306_-\|AzlC-family-ABC-transporter-permease	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	2.21364e-51
NZ_CP007572.1\|WP_000730413.1\|2069259_2070648_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.85719e-46
NZ_CP007572.1\|WP_001182060.1\|2091698_2092478_-\|uridine-phosphorylase	gnl\|CDD\|350167	cd17767, UP_EcUdp-like, uridine phosphorylases similar to Escherichia coli Udp and related phosphorylases. Uridine phosphorylase (UP) is specific for pyrimidines, and is involved in pyrimidine salvage and in the maintenance of uridine homeostasis. In addition to E. coli Udp, this subfamily includes Shewanella oneidensis MR-1 UP and Plasmodium falciparum purine nucleoside phosphorylase (PfPNP). PfPNP is an outlier in terms of genetic distance from the other families of PNPs. PfPNP is catalytically active for inosine and guanosine, and in addition, has a weak UP activity. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	4.65794e-137
NZ_CP007572.1\|WP_000610953.1\|2062300_2062624_-\|AzlD-domain-containing-protein	gnl\|CDD\|226827	COG4392, COG4392, Predicted membrane protein [Function unknown].	1.54249e-14
NZ_CP007572.1\|WP_000459243.1\|2086686_2088327_-\|hypothetical-protein	gnl\|CDD\|226987	COG4640, COG4640, Predicted membrane protein [Function unknown].	3.05926e-08
NZ_CP007572.1\|WP_000010479.1\|2084210_2085095_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	4.43223e-85
NZ_CP007572.1\|WP_000145175.1\|2071438_2073940_-\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NZ_CP007572.1\|WP_000453156.1\|2089774_2090446_-\|deoxyribose-phosphate-aldolase	gnl\|CDD\|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	3.60689e-110

>NZ_CP007572.1|WP_000887149.1|2077915_2078455_-|transcription-termination/antitermination-protein-NusG
MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIPTQTVNVEKNGKTKEIEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPTPLLEEEIRSILISMGQTVDVFDTNIKEGDVVQIIDGAFIGQEGRVVEIENNKVKLMINMFGSETQAELELYQVAEL
>NZ_CP007572.1|WP_000953631.1|2076932_2077778_-|patatin-family-protein
MLSVGLVLEGGGMRGLYTAGVLDAFLDAGIKVDGIVSVSAGALFGVNFVSRQRERALRYNKKYLSHPKYMSLRSWLRTGNFVNKDFTYYEVPMKLDVFDDEAFKKSNIDFYAVATEMTSGKPEYFKIDSVFEQMEILRASSALPVVSKMVDWQGKKYLDGGLSDSIPVDFARGLGFDKLIVVMTRPLNYQKKPSSGRLYKTLYRKYPNFVKTASNRYQQYNNSLEKVMSLEKTGDLFAIRPSKSLVIGRLEKNPDKLDSIYQLGMKDAKSMMPELNSYLMK
>NZ_CP007572.1|WP_000074728.1|2075642_2076890_+|MFS-transporter
MSPLNINKNNWRALIAAIVASGTDDLNIMFLAFSMSTIITDLHLSAAQAGWIGTITNLGMLVGGLIFGLLADRYNKFKVFKWTILIFSIATGLVFFTTNLSYLYIMRFIAGIGVGGEYGIAIAIMAGIVPANKMGRISSLNGIAGQVGSISSALLAGWLAPALGWRGLFLFGLLPIVLVLWMQFAIDDKDILDQYNTDADDEPLDISIKALFDTPVLATQSLALMVMTTVQIAGYFGMMNWLPTIIQTNLNVSIKNSSLWMIATILGMCLGMLVFGQLLDKFGPRLVYGCFLLSSAICVYLFQFATTMPSMIIGGAIVGFFVNGMFAGYGAMITRLYPHHIRSTANNLILNVGRAIGGFSSVIIGMILDVSNVSMVMLFLASLYIVSFLSMLSIKQLKRQKYHTNLTQLDVKPTD
>NZ_CP007572.1|WP_000564842.1|2074110_2075244_-|ISAs1-like-element-IS1548-family-transposase
MIDFIISIDDCAVELDSRQSWKIRYPLSTILFLVFVCQLAGIETWKEMEDFIEMNEPLFATYVDLSEGCPSHDTLERVISLVNSDRLKELKVQFEQSLTSLDAVHQLISVDGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVEEKSNEIVAIPQLLRTIDIRKSIVTIDAMGTQMAIVDTIIKGKADYCLAVKGNQETLYDDIALYFSDVNLLEELQENAQYYQTVEKSRGQIEVREYWVSSDIKWLCQNHPKWHKLRGIGMTRNTIDKDGQLSQENRYFIFSFKPDVLTFANCVRGHWQIESMHWLLDVVYHEDHHQTLDKRAAFNLNLIRKLCLYFLKVMVFPKKDLSYRRKQRYISVHLEDYLVQLFGERG
>NZ_CP007572.1|WP_000145175.1|2071438_2073940_-|leucine--tRNA-ligase
MTFYNHKEIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGHNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVEELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDAITTADQAEAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPVWIADYVLASYGTGAIMAVPAHDERDWEFAKQFKLDIIPVLEGGNVEEAAFTEDGLHINSDFLDGLDKASAIAKMVEWLEAEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPHNTEKLADEELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITTKEITEENSGALDKVYNETVKAVTEQVDQMKFNTAIAQLMVFVNAANKEDKLFSDYAKGFVQLIAPFAPHLGEELWQVLTASGESISYVPWPSYDESKLVENEIEIVVQIKGKVKAKLVVAKDLSREELQDLALANEKVQSEIAGKDIIKVIAVPNKLVNIVVK
>NZ_CP007572.1|WP_000903269.1|2070740_2071349_+|hypothetical-protein
MLHSKKIHSLSLIAVLSLATYTSLQPNHVTAEQSQKTSTVHMSQKTIEHKLKVADKEAAPLYAKIDHIQRHIEVKKAKDLKVIELYINKDINQLEKQNKRLLTKFYTSIDNQTWDSTSEVKKLIDKTNLSTNEKNRLKLYFEQRAYLETRLNDRYQKFDNSIENQNKELKILTSKIEKIYQKHGITKEVLKTYYAKKTVRAD
>NZ_CP007572.1|WP_000730413.1|2069259_2070648_+|HAMP-domain-containing-histidine-kinase
MKKKSLISNLILINSITLFLGFYLIYFSVNYVIKDYVHQMTRNSMQANFTILDSIYNNKKIPDENMVNQDSIFVWSYYAIFDQHYRMKYGTDNHKKESHDIIRYLTQKRLWQISKEKDGMFVTIKKKNYYVMTKDYSGILVDGSIKKVPKAQSQLFHVINFSDITYTQHLITKINHFLIVILVLTYIPMLFIMRKTFTGIRESIQSVQTYISSLWKNQGNHQSSQKEIVFSDFDPLLLESQEMANRIYQAEESQRNFFQNASHELRTPLMSIQGYTEGVQEGIIDAELAHSVILQESKKMKQLVDDIILLSKLDSNLSDQKDEFSLNELLNSIIAYFKPLANKQKISITYRPDEHEKLLKGNEELIQRAINNILSNALRYAVSHIEISYTNQKLTISNDGPAISKEDLPYIFDRFYKGHGGQTGIGLAMTKEIIKQHHGNIIAESDSTSTTFTIYFNCHKIA
>NZ_CP007572.1|WP_000161343.1|2068576_2069263_+|response-regulator-transcription-factor
MTKIIYFADDEKNIRDLVVPFLEHDGFTVRAFETGDLLLEAYKNQKPDLVILDIMMPGTNGLDVMKSIRQYDNVPIIMLTARDSDVDFITAFNLGTDDYFTKPFSPIKLSLHVKALFKRLDEKAIKNDTQYQFLDLTLDTEKRIALLSNEEMPLTKTEFDFLLVLIEKPETAFSRETLLNRIWGFDDIESRAVDDTIKRLRKKFKQYHSQVSIKTVWGYGFKLIKEDK
>NZ_CP007572.1|WP_000410681.1|2062613_2063306_-|AzlC-family-ABC-transporter-permease
MEKGFKEGVKDALPTALGYISIGLAFGIVASASDLSAIEVGLMSALVYGGSAQFAMCALLLAKADLMTITMTVFLVNLRNMLMSLHATTIFKSAHLMNQLAIGTLITDESYGVLLGEALHHKVVSPSWMHGNNVMSYLTWVISTIIGTLLGSTIPNPEMFGLDFALVAMFIGLFVFQLFGMLSDGKRLVVYVLASVGLSYFLLATFLSGALSVLLATVVGCSVGVVLDDK
>NZ_CP007572.1|WP_000610953.1|2062300_2062624_-|AzlD-domain-containing-protein
MINSTVFLAILLGFVVSWVPRVAPFIFVKYKGLPNSLVKFLKFLPLSILFALTFSSFFSVKLGQLPTLKWLDLLAGIPTLVVTIRYRNLFYTVLTGIVTMALLRLLF
>NZ_CP007572.1|WP_000497678.1|2081435_2081609_-|preprotein-translocase-subunit-SecE
MFVKGIFQVLRDTTWPNRKQRWKDFISILEYTVFFTIVIYIFDKLLAAGVMDLINRF
>NZ_CP007572.1|WP_000057521.1|2081644_2081797_-|50S-ribosomal-protein-L33
MAQKKASLACTECGSRNYSIGVSSTPKPTRLEVNKFCKYCKKYTIHKETR
>NZ_CP007572.1|WP_000764814.1|2081845_2084167_-|penicillin-binding-protein
MKLFDKFIDLFRVDEDNDEMTRKNEQETREETSNLDGEEVYDIDDITRPSKSQYQRGIRHQKKNAKSRPEWLQKVDRYLPSPKNPIRRFWRRYRIGKLLFIALMAFILIFGSYLFYLSKTATVSDLQSALKTTTTIYDKNKEYAGKLSGQKGTYVELNAISDHLKNAVIATEDRTFYENNGVNFKRFFLAVATLGKFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTKKYSKAEILTMYLNNSYFGNGVWGVEDASRKYFGTSAANLTVDEAATLAGMLKGPEVYNPYYSVENATNRRDTVLAAMVDAGKLTKSQAKEAASIGMKNRLADTYAGKINDYRYPSYFDAVVNEAIDTYGISEKDIVNNGYKIYTALDQNYQSGMQKTFDDTSLFPVSDYDGQSAQGASVALDPKTGGVRGLVGRVQSTKDAQFRSFNYATQSKRSPASTIKPLVVYSPAIASGWSIDKELPNKVQDFHGYKPSNYGGIETESIPMYQALANSYNIPAVYTLDKLGINKAFTYGRKFGLNMSSANKELGVALGGSVTTNPLEMAQAYSTFANDGIMHRAHLITRIETANGKLVKQFTDKPKRVISRSVASKMTSMMLGTFSNGTAINANVYGYTMAGKTGTTETDFNPNLSGDQWVVGYTPDVVISQWVGFKNTDKHHYLTDSSAGTASNIFSTQASYILPYTKGSSFTHIENAYFQNGIGSVYNAQDASNTTNQESRSIINDLKDSASKAAQDISRAVEDSNFQEKVKDAWNSLKDYFR
>NZ_CP007572.1|WP_000010479.1|2084210_2085095_+|RluA-family-pseudouridine-synthase
MSFSLKIRNPYGEHTVKELLEDYFLIPRKIRHFLRVKKHVLINNEFINWQTVVQENDTITLIFDDEDYPTKKIPLGRAELIDCLYEDEHLIIVNKPEGMKTHGNQPNEIALLNHVSAYSGQTCYVVHRLDMETSGAVLFAKNPFILPLINQRLERKEIWREYWALVEGKFSPKHQVLRDKIGRNRHDRRKRIIDSKNGQHAMTIIDVLKYTQNSSLIKCRLETGRTHQIRVHLSHHGHPLIGDPLYNPSSNNERLMLHAHRLTLSHPLTCETISVEAPSSTFEKILNNYKKRVG
>NZ_CP007572.1|WP_041326819.1|2085048_2086551_-|IS1182-family-transposase
MFHKENPEYNRRQVGFYTLDELVPKDHFLRKVEETIDFSFIYDLVEDSYSSDNGRPSLDPVLLVKIPLIQCFYGIRSMRQTIKDIEVNTAYRWFLGLSLDDKVPHFTTYGKNYSRRFENKEVLAHIFSHVLHHVLEAGLIDPSEIFIDGTHIKAAANNHKYKNVVIDQKAKFMSEQLETEINLDRRKHAKKFLKPAKKGEAKPKKQSTTDPDSGWFHKGEHKEVFAYNAQVACDKHGWALAYTVESGNTHDSQAFPALFAKLEPFSPEFIIADSGYKTPSIAKFLLEKGITPVFPYTRPRGKKDFLHPKDFVYDEHFDCYLCPENQVLTYRTTTREGYREYKSNPKICKTCPLLAICTESRQYQKVVVRHIWKDALEVCEDIRHQSDMKELYQHRKETIERLFGTAKEYHNLRYTREKGKSKMEAKVGLTLACLNIKKLVKMMTGKTCYFTQISQYYWFMGEFGKNIKKTNIKNDVCLHSESWIIIIQLFFYNCLKSSRK
>NZ_CP007572.1|WP_000459243.1|2086686_2088327_-|hypothetical-protein
MFDFFKKKVVKVCLVIFGIVLVSLLSLGFFYFSKGQVLSRFVAARSRTSGQAFDNIKEYMVWSDTGESITNDEANYANFEPLSKSEARKLGQEIKEGNKNDSMYLKRVGSRLGIFPDYRIANKPMSLTLKTNVPKLDVLLNQKKVATSNSDHFSVTVERLPRTHYTASLEGTSDGKEIKLKKDYDGKNQTIDLSVAFKSFTVTSNLMDGNLYFGDNRIAKLKDGSYSVENYPVTDGSKAYIKKVFNDGEITSHKQKLISIADNQTIKLDVDGLLNEKEAGQKLITAFNQLILYVSTGQDPQTLGTVFEKGAENDFYKGLKESIKAKFVTDNRKASHFTIPNIVLNKMTQVGKESYQVNFAADYDFNYDKSTDPDKKTYGHIIQNLTGNFIMKKSGNSYLISNDGKKDITVAKETNKVKADPVSIFPENLVGSWKGEVEDGTVTMTFDKDGKVTQKKVYKDSKSKESNHSAKVTKLEDKGNGLYLYQYESGTDTTTFVTGGIGGLKVKYAYGIKVEGNKVIPVIWQTSSDGEFDYHKPLLSKPLTKQ
>NZ_CP007572.1|WP_041326822.1|2088496_2089708_-|phosphopentomutase
MSQFDRIHLVVLDSVGIGVAPDANDFVNAGVPDGASDTLGHISKTVGLAVPNMAKIGLGNIPRPQALKTVPAEENPSGYATKLQEVSLGKDTMTGHWEIMGLNITEPFDTFWNGFPEDIITKIEDFSGRKVIREANKPYSGTAVIDDFGPRQMETGELIVYTSADPVLQIAAHEDIIPLEELYRICEYARSITMERPALLGRIIARPYVGEPGNFTRTANRHDYAVSPFEDTVLNKLDQAGIDTYAVGKINDIFNGSGINHDMGHNKSNSHGIDTLIKTMGLSEFEKGFSFTNLVDFDALYGHRRDPHGYRDCLHEFDERLPEIISAMRDKDLLLITADHGNDPTYAGTDHTREYIPLLAYSPSFTGNGLIPVGHFADISATVADNFGVDTAMIGESFLQDLV
>NZ_CP007572.1|WP_000453156.1|2089774_2090446_-|deoxyribose-phosphate-aldolase
MEVKDILKTVDHTLLATTATWPEIQTILDDAMAYKTASACIPASYVKKAAEYVSGKLAICTVIGFPNGYSTTAAKVFECQDAIKNGADEIDMVINLTDVKNGDFDTVEEEIRQIKAACQDHILKVIVETCQLTKEELIELCGVVTRSGADFIKTSTGFSTAGATFEDVEVMAKYVGEGVKIKAAGGISSLEDAEKFIALGASRLGTSRIIKIVKNQKVEEGTY
>NZ_CP007572.1|WP_001159688.1|2090475_2091678_-|NupC/NupG-family-nucleoside-CNT-transporter
MQFIYSIIGILLVLGIVYAISFNRKSVSLSLIGKALIVQFIIALILVRIPLGQQVVSVVSTGVTKVINCGQAGLNFVFGSLADSGAKTGFIFAIQTLGNIVFLSALVSLLYYVGILGFVVKWIGKGVGKIMKSSEVESFVAVANMFLGQTDSPILVSKYLGRMTDSEIMVVLVSGMGSMSVSILGGYIALGIPMEYLLIASTMVPIGSILIAKILLPQTEPVQKIDDIKMDNKGNNANVIDAIAEGASTGAQMAFSIGASLIAFVGLVSLINMMLSGLGIRLEQIFSYVFAPFGFLMGFDHKNILLEGNLLGSKLILNEFVSFQQLGHLIKSLDYRTALVATISLCGFANLSSLGICVSGIAVLCPEKRGTLARLVFRAMIGGIAVSMLSAFIVGIVTLF
>NZ_CP007572.1|WP_001182060.1|2091698_2092478_-|uridine-phosphorylase
MQNYSGEVGLQYHLQIRPGDVGRYVIMPGDPKRCAKIAEHFDNAVLVADSREYVTYTGTLNGEKVSVTSTGIGGPSASIAMEELKLCGADTFIRVGTCGGIDLDVKGGDIVIATGAIRMEGTSKEYAPIEFPAVADLEVTNALVNAAKKLGYTSHAGVVQCKDAFYGQHEPERMPVSYELLNKWEAWKRLGTKASEMESAALFVAASHLGVRCGSDFLVVGNQERNALGMDNPMAHDTEAAIQVAVEALRTLIENDKSQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP007572_3	3.7\|2079211\|18\|NZ_CP007572\|CRT	2079211-2079228	18	NZ_CP007572.1	2078851-2078868	1	0.944

1. spacer 3.7|2079211|18|NZ_CP007572|CRT matches to position: 2078851-2078868, mismatch: 1, identity: 0.944

ttggcttctggtttggcc	CRISPR spacer
ttggcttctggtttagcc	Protospacer
**************.***

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007572_1	1.2\|998645\|29\|NZ_CP007572\|CRISPRCasFinder	998645-998673	29	MK448729	Streptococcus phage Javan31, complete genome	33403-33431	0	1.0
NZ_CP007572_1	1.2\|998645\|29\|NZ_CP007572\|CRISPRCasFinder	998645-998673	29	MK448691	Streptococcus phage Javan17, complete genome	33403-33431	0	1.0
NZ_CP007572_1	1.2\|998645\|29\|NZ_CP007572\|CRISPRCasFinder	998645-998673	29	MK448948	Streptococcus phage Javan46, complete genome	33347-33375	0	1.0
NZ_CP007572_1	1.2\|998645\|29\|NZ_CP007572\|CRISPRCasFinder	998645-998673	29	MK448768	Streptococcus phage Javan47, complete genome	35055-35083	0	1.0
NZ_CP007572_2	2.1\|1141327\|25\|NZ_CP007572\|CRISPRCasFinder	1141327-1141351	25	AP013358	Uncultured Mediterranean phage uvMED DNA, complete genome, group G1, isolate: uvMED-CGR-U-MedDCM-OCT-S27-C45	25656-25680	3	0.88
NZ_CP007572_2	2.1\|1141327\|25\|NZ_CP007572\|CRISPRCasFinder	1141327-1141351	25	MG711463	Faecalibacterium phage FP_oengus, complete genome	52130-52154	4	0.84
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	NZ_CP024772	Bacillus thuringiensis LM1212 plasmid pLM1, complete sequence	40319-40347	6	0.793
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	NZ_LN906635	Lactobacillus reuteri plasmid p53608_1, complete genome, strain ATCC 53608	48868-48896	6	0.793
NZ_CP007572_1	1.4\|998635\|39\|NZ_CP007572\|CRT	998635-998673	39	MK448729	Streptococcus phage Javan31, complete genome	33393-33431	6	0.846
NZ_CP007572_1	1.4\|998635\|39\|NZ_CP007572\|CRT	998635-998673	39	MK448691	Streptococcus phage Javan17, complete genome	33393-33431	6	0.846
NZ_CP007572_1	1.4\|998635\|39\|NZ_CP007572\|CRT	998635-998673	39	MK448948	Streptococcus phage Javan46, complete genome	33337-33375	6	0.846
NZ_CP007572_1	1.4\|998635\|39\|NZ_CP007572\|CRT	998635-998673	39	MK448768	Streptococcus phage Javan47, complete genome	35045-35083	6	0.846
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	NC_020879	Aeromonas phage Aes012, complete genome	134557-134585	7	0.759
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	MH179477	Aeromonas phage 60AhydR15PP, complete genome	133527-133555	7	0.759
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	NC_008208	Aeromonas phage 25, complete genome	134599-134627	7	0.759
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	NC_014635	Aeromonas phage phiAS4, complete genome	33180-33208	7	0.759
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	DQ529280	Aeromonas salmonicida bacteriophage 25, complete genome	134599-134627	7	0.759
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	MF479730	Aeromonas phage AS-gz, complete genome	51898-51926	7	0.759
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	JX306041	Stenotrophomonas phage IME13, complete genome	139584-139612	7	0.759
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	MH179476	Aeromonas phage 50AhydR13PP, complete genome	93640-93668	7	0.759
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	NC_019543	Aeromonas phage Aes508, complete genome	133764-133792	7	0.759
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	CP016197	Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-3, complete sequence	84106-84134	7	0.759
NZ_CP007572_1	1.1\|998579\|29\|NZ_CP007572\|CRISPRCasFinder	998579-998607	29	MF417965	Uncultured Caudovirales phage clone 3S_17, partial genome	3160-3188	7	0.759
NZ_CP007572_3	3.5\|2079103\|30\|NZ_CP007572\|CRT	2079103-2079132	30	NC_028835	Lactobacillus phage CL2, complete genome	3497-3526	7	0.767
NZ_CP007572_3	3.5\|2079103\|30\|NZ_CP007572\|CRT	2079103-2079132	30	KR905066	Lactobacillus phage CL1, complete genome	2482-2511	7	0.767
NZ_CP007572_3	3.5\|2079103\|30\|NZ_CP007572\|CRT	2079103-2079132	30	NC_028911	Lactobacillus phage iLp1308, complete genome	2578-2607	7	0.767
NZ_CP007572_3	3.8\|2079247\|30\|NZ_CP007572\|CRT	2079247-2079276	30	NC_048797	Bacillus phage vB_BmeM-Goe8, complete genome	33781-33810	7	0.767
NZ_CP007572_3	3.3\|2078995\|30\|NZ_CP007572\|CRT	2078995-2079024	30	MN855875	Bacteriophage sp. isolate 328, complete genome	1403-1432	9	0.7

1. spacer 1.2|998645|29|NZ_CP007572|CRISPRCasFinder matches to MK448729 (Streptococcus phage Javan31, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatagtcgcacaaacagcgaacag	CRISPR spacer
aatacaatagtcgcacaaacagcgaacag	Protospacer
*****************************

2. spacer 1.2|998645|29|NZ_CP007572|CRISPRCasFinder matches to MK448691 (Streptococcus phage Javan17, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatagtcgcacaaacagcgaacag	CRISPR spacer
aatacaatagtcgcacaaacagcgaacag	Protospacer
*****************************

3. spacer 1.2|998645|29|NZ_CP007572|CRISPRCasFinder matches to MK448948 (Streptococcus phage Javan46, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatagtcgcacaaacagcgaacag	CRISPR spacer
aatacaatagtcgcacaaacagcgaacag	Protospacer
*****************************

4. spacer 1.2|998645|29|NZ_CP007572|CRISPRCasFinder matches to MK448768 (Streptococcus phage Javan47, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatagtcgcacaaacagcgaacag	CRISPR spacer
aatacaatagtcgcacaaacagcgaacag	Protospacer
*****************************

5. spacer 2.1|1141327|25|NZ_CP007572|CRISPRCasFinder matches to AP013358 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G1, isolate: uvMED-CGR-U-MedDCM-OCT-S27-C45) position: , mismatch: 3, identity: 0.88

accttggcttctgttttctgcatcg	CRISPR spacer
agcttgacttctgttttctgcatct	Protospacer
* ****.*****************

6. spacer 2.1|1141327|25|NZ_CP007572|CRISPRCasFinder matches to MG711463 (Faecalibacterium phage FP_oengus, complete genome) position: , mismatch: 4, identity: 0.84

accttggcttctgttttctgcatcg	CRISPR spacer
gccttggcttcttttttctgcttca	Protospacer
.*********** ******** **.

7. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to NZ_CP024772 (Bacillus thuringiensis LM1212 plasmid pLM1, complete sequence) position: , mismatch: 6, identity: 0.793

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
tgatatgttatttgatgatgtaacattag	Protospacer
**  **************** **** .*

8. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to NZ_LN906635 (Lactobacillus reuteri plasmid p53608_1, complete genome, strain ATCC 53608) position: , mismatch: 6, identity: 0.793

tgcaatgttatttgatgatggaacaacat-	CRISPR spacer
tgcaactttatttgatgatggaa-agtaca	Protospacer
*****. **************** *..*.

9. spacer 1.4|998635|39|NZ_CP007572|CRT matches to MK448729 (Streptococcus phage Javan31, complete genome) position: , mismatch: 6, identity: 0.846

-attccaaaacaatacaatagtcgcacaaacagcgaacag	CRISPR spacer
tactgc-gattaatacaatagtcgcacaaacagcgaacag	Protospacer
 *.* * .* .*****************************

10. spacer 1.4|998635|39|NZ_CP007572|CRT matches to MK448691 (Streptococcus phage Javan17, complete genome) position: , mismatch: 6, identity: 0.846

-attccaaaacaatacaatagtcgcacaaacagcgaacag	CRISPR spacer
tactgc-gattaatacaatagtcgcacaaacagcgaacag	Protospacer
 *.* * .* .*****************************

11. spacer 1.4|998635|39|NZ_CP007572|CRT matches to MK448948 (Streptococcus phage Javan46, complete genome) position: , mismatch: 6, identity: 0.846

-attccaaaacaatacaatagtcgcacaaacagcgaacag	CRISPR spacer
tactgc-gattaatacaatagtcgcacaaacagcgaacag	Protospacer
 *.* * .* .*****************************

12. spacer 1.4|998635|39|NZ_CP007572|CRT matches to MK448768 (Streptococcus phage Javan47, complete genome) position: , mismatch: 6, identity: 0.846

-attccaaaacaatacaatagtcgcacaaacagcgaacag	CRISPR spacer
tactgc-gattaatacaatagtcgcacaaacagcgaacag	Protospacer
 *.* * .* .*****************************

13. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to NC_020879 (Aeromonas phage Aes012, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

14. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to MH179477 (Aeromonas phage 60AhydR15PP, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

15. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to NC_008208 (Aeromonas phage 25, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

16. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to NC_014635 (Aeromonas phage phiAS4, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

17. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to DQ529280 (Aeromonas salmonicida bacteriophage 25, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

18. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to MF479730 (Aeromonas phage AS-gz, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

19. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to JX306041 (Stenotrophomonas phage IME13, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

20. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to MH179476 (Aeromonas phage 50AhydR13PP, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

21. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to NC_019543 (Aeromonas phage Aes508, complete genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ttatgctttatttgatgatgaaacaacat	Protospacer
*   .. *************.********

22. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to CP016197 (Bacillus thuringiensis serovar coreanensis strain ST7 plasmid pST7-3, complete sequence) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
tgatatgttatttgatgatgtaacattgg	Protospacer
**  **************** **** ..

23. spacer 1.1|998579|29|NZ_CP007572|CRISPRCasFinder matches to MF417965 (Uncultured Caudovirales phage clone 3S_17, partial genome) position: , mismatch: 7, identity: 0.759

tgcaatgttatttgatgatggaacaacat	CRISPR spacer
ctcattggtatttgatgatggaacataaa	Protospacer
. ** ** *****************  *

24. spacer 3.5|2079103|30|NZ_CP007572|CRT matches to NC_028835 (Lactobacillus phage CL2, complete genome) position: , mismatch: 7, identity: 0.767

-ttaacgtctggtttggcttctggcttaacg	CRISPR spacer
attcat-tctggtttgccttctggcttagta	Protospacer
 ** *. ********* ***********...

25. spacer 3.5|2079103|30|NZ_CP007572|CRT matches to KR905066 (Lactobacillus phage CL1, complete genome) position: , mismatch: 7, identity: 0.767

-ttaacgtctggtttggcttctggcttaacg	CRISPR spacer
attcat-tctggtttgccttctggcttagta	Protospacer
 ** *. ********* ***********...

26. spacer 3.5|2079103|30|NZ_CP007572|CRT matches to NC_028911 (Lactobacillus phage iLp1308, complete genome) position: , mismatch: 7, identity: 0.767

-ttaacgtctggtttggcttctggcttaacg	CRISPR spacer
attcat-tctggtttgccttctggcttagta	Protospacer
 ** *. ********* ***********...

27. spacer 3.8|2079247|30|NZ_CP007572|CRT matches to NC_048797 (Bacillus phage vB_BmeM-Goe8, complete genome) position: , mismatch: 7, identity: 0.767

ttagcttctggcttaacgtctggcttaaca	CRISPR spacer
tctgcttctggcttaacctctggctctgct	Protospacer
*. ************** *******. .*

28. spacer 3.3|2078995|30|NZ_CP007572|CRT matches to MN855875 (Bacteriophage sp. isolate 328, complete genome) position: , mismatch: 9, identity: 0.7

ctggcctctggcttaacgtctggtttaatt	CRISPR spacer
gtggcctctggctcaacgtctgcgccatcc	Protospacer
 ************.********  ..* ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

44006 : 52213

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000638884.1\|44006_45461_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.7e-54	32.7
WP_001293628.1\|45488_46514_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	8.1e-64	42.7
WP_000717515.1\|46776_47328_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.7e-26	35.8
WP_000780014.1\|47350_48103_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000166561.1\|48122_49670_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.0e-78	50.2
WP_001045909.1\|49862_50762_+	peptidoglycan DD-metalloendopeptidase family protein	A0A221J6U0	Arthrobacter_phage	4.1e-19	45.9
WP_000783416.1\|50908_52213_+	LysM peptidoglycan-binding domain-containing protein	A0A2D1GNZ3	Streptomyces_phage	4.9e-05	40.5

DBSCAN-SWA_2

184236 : 263493

Streptococcus_phage(48.15%)

tRNA,holin,integrase,protease,transposase

attL 243803:243821|attR 263918:263936

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001269501.1\|184236_184947_+	metal ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.6e-08	24.9
WP_000923270.1\|184936_185749_+	metal ABC transporter permease	NA	NA	NA	NA
WP_000777421.1\|185959_186991_-	hypothetical protein	NA	NA	NA	NA
WP_041326046.1\|187689_188835_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	2.3e-107	53.8
WP_052471775.1\|189028_189619_-	helix-turn-helix transcriptional regulator	A0A1X9I723	Streptococcus_phage	7.6e-14	65.1
WP_003066809.1\|189841_190045_+	transcriptional regulator	NA	NA	NA	NA
WP_024053155.1\|190059_190467_+	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	1.4e-35	57.5
WP_041326052.1\|190483_191230_+	hypothetical protein	A0A0A7RW33	Clostridium_phage	7.3e-22	49.6
WP_024053153.1\|191220_191853_+	phage protein	R9QNB1	Lactococcus_phage	1.0e-32	43.4
WP_024053152.1\|192300_192828_+	hypothetical protein	NA	NA	NA	NA
WP_041326054.1\|192990_193227_+	hypothetical protein	NA	NA	NA	NA
WP_024053150.1\|193223_193574_+	HTH domain-containing protein	A0A218MNC1	uncultured_virus	2.0e-06	36.8
WP_041326056.1\|193576_193849_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	3.2e-20	53.5
WP_041326058.1\|193845_194010_+	hypothetical protein	NA	NA	NA	NA
WP_041326060.1\|194144_195002_+	phage protein	A0A1X9I6L2	Streptococcus_phage	1.0e-123	74.7
WP_041326850.1\|195084_196533_+	DNA primase	Q9AZI5	Lactococcus_phage	8.8e-72	40.5
WP_024053143.1\|197972_198416_+	DUF1492 domain-containing protein	A0A1S5S8W3	Streptococcus_phage	7.9e-08	28.5
WP_024053142.1\|198463_199042_+	hypothetical protein	NA	NA	NA	NA
WP_041326062.1\|199041_199377_+	hypothetical protein	NA	NA	NA	NA
WP_003038349.1\|200155_200347_+	type II toxin-antitoxin system HicA family toxin	A0A1X9I5T5	Streptococcus_phage	1.7e-23	83.9
WP_041326065.1\|200383_200764_+	antitoxin HicB	A0A1X9I5X0	Streptococcus_phage	4.7e-49	76.0
WP_041326067.1\|201028_202288_-\|tRNA	tyrosine--tRNA ligase	A0A1S6UA79	Serratia_phage	8.1e-74	41.2
WP_041326069.1\|202398_204696_+	penicillin-binding protein	NA	NA	NA	NA
WP_000907191.1\|205219_208795_+	DNA-directed RNA polymerase subunit beta	A0A2P0VMZ3	Tetraselmis_virus	9.8e-40	26.1
WP_000228729.1\|208911_212562_+	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	2.6e-64	25.1
WP_000285374.1\|212675_213041_+	DUF1033 family protein	NA	NA	NA	NA
WP_001292556.1\|213731_215009_+	group II intron reverse transcriptase/maturase	NA	NA	NA	NA
WP_017771557.1\|215058_216471_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.7e-208	76.5
WP_000250798.1\|216635_217607_+	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_094248948.1\|218478_219713_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	3.4e-64	50.0
WP_000793378.1\|219975_220431_+	competence protein ComGF	NA	NA	NA	NA
WP_000601101.1\|220408_220780_+	hypothetical protein	NA	NA	NA	NA
WP_001008569.1\|220894_221869_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000047534.1\|221900_223094_+	acetate kinase	NA	NA	NA	NA
WP_001872485.1\|223407_223659_+	hypothetical protein	NA	NA	NA	NA
WP_000008108.1\|223727_224393_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_001881026.1\|224413_225184_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	9.8e-30	34.6
WP_001281321.1\|225253_226321_-	glutamyl aminopeptidase	NA	NA	NA	NA
WP_000660182.1\|226505_226745_-	hypothetical protein	NA	NA	NA	NA
WP_000791272.1\|226905_227190_+	DUF4651 domain-containing protein	NA	NA	NA	NA
WP_000602780.1\|227186_227510_+	thioredoxin family protein	NA	NA	NA	NA
WP_000578324.1\|227542_228169_+\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_000282446.1\|229018_229414_+	single-stranded DNA-binding protein	A1EAD1	Streptococcus_phage	3.3e-29	50.0
WP_000416614.1\|229537_230182_+	HAD family hydrolase	A0A1D8KNV9	Synechococcus_phage	2.9e-11	29.2
WP_000930328.1\|230208_231954_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	1.3e-58	29.2
WP_000683317.1\|232848_233304_+	CidA/LrgA family protein	NA	NA	NA	NA
WP_000421730.1\|233305_234034_+\|holin	antiholin-like protein LrgB	NA	NA	NA	NA
WP_000170509.1\|234276_235905_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000680645.1\|236017_236995_+	ABC transporter permease	NA	NA	NA	NA
WP_000603397.1\|236991_237813_+	ABC transporter permease	NA	NA	NA	NA
WP_000140980.1\|237824_238628_+	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	4.2e-07	26.9
WP_000171306.1\|238611_239238_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.3e-16	27.0
WP_000434616.1\|239520_241551_+	PTS system trehalose-specific EIIBC component	NA	NA	NA	NA
WP_000151015.1\|241772_243398_+	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_000228186.1\|243613_245650_+	BglG family transcription antiterminator	NA	NA	NA	NA
243803:243821	attL	NA	NA	NA	NA
WP_000944235.1\|245652_245937_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_000677351.1\|245949_247305_+	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_000203493.1\|247307_248165_+	transketolase	NA	NA	NA	NA
WP_001203822.1\|248161_249091_+	transketolase	NA	NA	NA	NA
WP_001203064.1\|249199_250459_+	oxidoreductase	NA	NA	NA	NA
WP_001018249.1\|250546_250816_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_000043841.1\|251196_253326_+	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_000204781.1\|253327_254080_+	SseB family protein	NA	NA	NA	NA
WP_000539954.1\|254088_254673_+	serine O-acetyltransferase	NA	NA	NA	NA
WP_000656476.1\|254682_254865_+	lipoprotein	NA	NA	NA	NA
WP_000591130.1\|254861_256205_+\|tRNA	cysteine--tRNA ligase	A0A1V0SAQ2	Catovirus	1.3e-53	31.7
WP_000568029.1\|256197_256584_+	Mini-ribonuclease 3	NA	NA	NA	NA
WP_041326110.1\|256709_258179_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.5
WP_000178021.1\|258246_259002_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000716636.1\|258998_259517_+	hypothetical protein	NA	NA	NA	NA
WP_000143135.1\|259609_260470_+	DegV family protein	NA	NA	NA	NA
WP_000793594.1\|261007_261130_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001867156.1\|261351_261798_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_000035940.1\|261818_262211_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_000022172.1\|262338_263493_-\|integrase	site-specific integrase	A0A1S5S7K9	Streptococcus_phage	2.7e-47	33.4
263918:263936	attR	NA	NA	NA	NA

DBSCAN-SWA_3

326618 : 334140

Bacillus_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000593862.1\|326618_327362_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-29	38.1
WP_000478229.1\|327483_327708_+	DUF4059 family protein	NA	NA	NA	NA
WP_000272353.1\|327776_328691_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.1e-87	52.8
WP_000276183.1\|328848_330309_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.4e-100	42.3
WP_000174854.1\|330305_331127_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	7.7e-73	55.1
WP_041326139.1\|331255_332716_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.5
WP_000041114.1\|332805_334140_+	aminopeptidase C	R4TV59	Phaeocystis_globosa_virus	1.1e-63	33.3

DBSCAN-SWA_4

590139 : 653270

Streptococcus_phage(73.44%)

portal,capsid,terminase,holin,integrase,transposase,tail

attL 590222:590281|attR 649045:650541

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041326161.1\|590139_591618_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.5
590222:590281	attL	NA	NA	NA	NA
WP_000710757.1\|591821_592082_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_000583233.1\|592190_593126_-	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_000189636.1\|593391_594414_+	adenosine deaminase	NA	NA	NA	NA
WP_001162136.1\|594472_594916_+	flavodoxin	NA	NA	NA	NA
WP_000418127.1\|594992_595268_+	chorismate mutase	NA	NA	NA	NA
WP_000595706.1\|595260_596457_+	voltage-gated chloride channel family protein	A0A1X9I5Z9	Streptococcus_phage	3.6e-103	54.5
WP_001068667.1\|597040_597388_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_000264730.1\|597612_598692_-\|integrase	site-specific integrase	A0A1X9IGD8	Lactococcus_phage	3.2e-63	39.8
WP_000505363.1\|598815_599019_-	hypothetical protein	O34033	Streptococcus_phage	1.7e-10	48.4
WP_000891067.1\|599121_599679_-	GTP pyrophosphokinase	Q0H269	Geobacillus_phage	1.6e-18	30.2
WP_000002266.1\|599680_600424_-	helix-turn-helix transcriptional regulator	A0A097PBE5	Streptococcus_pyogenes_phage	1.4e-78	63.7
WP_001107539.1\|600927_601152_-	DUF2188 domain-containing protein	E8ZD70	Streptococcus_phage	2.2e-22	67.6
WP_000039331.1\|601515_602211_-	hypothetical protein	M1PL51	Streptococcus_phage	6.8e-30	41.6
WP_000164461.1\|602264_602480_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001072512.1\|602497_603223_+	phage antirepressor protein	A0A141E1D3	Streptococcus_phage	7.2e-107	81.2
WP_032459526.1\|603291_603516_+	hypothetical protein	A0A1S5SC19	Streptococcus_phage	2.3e-24	79.5
WP_000884083.1\|603450_604257_-	TIGR02391 family protein	A0A1S5SBU1	Streptococcus_phage	4.2e-124	82.8
WP_000360288.1\|604397_604733_-	hypothetical protein	J7KDN7	Streptococcus_phage	7.8e-16	69.1
WP_000263688.1\|604877_605063_+	helix-turn-helix transcriptional regulator	J7KH19	Streptococcus_phage	7.8e-26	95.1
WP_000879944.1\|605135_605366_+	hypothetical protein	NA	NA	NA	NA
WP_025194849.1\|605524_606373_+	DnaD domain protein	A0A097PBE7	Streptococcus_pyogenes_phage	1.1e-66	57.7
WP_000600244.1\|606359_607142_+	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	3.1e-132	88.8
WP_000431578.1\|607268_607544_+	hypothetical protein	J7KJY6	Streptococcus_phage	1.2e-41	96.7
WP_000229414.1\|607530_607785_+	hypothetical protein	J7KK18	Streptococcus_phage	5.7e-35	83.3
WP_000064172.1\|607949_608903_+	recombinase RecT	J7KDK3	Streptococcus_phage	5.1e-121	71.0
WP_000163581.1\|608899_609697_+	hypothetical protein	J7KGZ1	Streptococcus_phage	2.1e-131	84.9
WP_000435056.1\|609865_610207_+	hypothetical protein	M1PKX3	Streptococcus_phage	2.2e-13	42.0
WP_000067995.1\|610203_610716_+	hypothetical protein	A0A1S5S8V7	Streptococcus_phage	7.6e-63	72.0
WP_000127438.1\|610702_610900_+	hypothetical protein	A3F626	Streptococcus_phage	2.6e-11	91.9
WP_000954649.1\|610893_611178_+	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	1.1e-47	95.7
WP_000743215.1\|611174_611444_+	hypothetical protein	Q938M2	Temperate_phage	1.0e-42	91.0
WP_000612739.1\|611457_611874_+	hypothetical protein	Q938M1	Temperate_phage	3.2e-35	61.3
WP_000205525.1\|611870_612155_+	hypothetical protein	A3F628	Streptococcus_phage	4.9e-35	81.9
WP_001019149.1\|612298_612811_+	DUF1642 domain-containing protein	A0A097PAV5	Streptococcus_pyogenes_phage	2.7e-28	46.0
WP_001105090.1\|612831_613131_+	hypothetical protein	M1PFH6	Streptococcus_phage	1.3e-17	45.4
WP_000221696.1\|613318_613513_+	hypothetical protein	NA	NA	NA	NA
WP_000660741.1\|613509_613776_+	hypothetical protein	NA	NA	NA	NA
WP_000533372.1\|614170_614596_+	DUF1492 domain-containing protein	A0A0B5A564	Streptococcus_phage	2.9e-31	50.0
WP_000225343.1\|614889_615267_+	HNH endonuclease	Q7Y4J1	Streptococcus_phage	9.3e-42	71.3
WP_000725957.1\|615418_615775_+	hypothetical protein	A0A0B5A7G9	Streptococcus_phage	5.9e-22	49.6
WP_001108671.1\|615771_617040_+\|portal	phage portal protein	M1PFL4	Streptococcus_phage	1.1e-187	77.1
WP_000227332.1\|617032_618253_+	hypothetical protein	Q7Y4I9	Streptococcus_phage	2.1e-114	66.3
WP_000421992.1\|618252_618441_+	hypothetical protein	NA	NA	NA	NA
WP_000256853.1\|618549_619965_+\|terminase	terminase	A0A0B5A091	Streptococcus_phage	6.3e-216	74.8
WP_001288695.1\|620045_620510_+	DUF4355 domain-containing protein	A0A0B5A7G6	Streptococcus_phage	1.7e-40	51.3
WP_000841023.1\|620512_621415_+\|capsid	phage major capsid protein	A0A0B5A5W3	Streptococcus_phage	9.7e-146	86.0
WP_000640308.1\|621411_621627_+	hypothetical protein	M1PRX2	Streptococcus_phage	3.2e-07	49.3
WP_000180798.1\|621640_622063_+	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	2.4e-46	68.6
WP_025194588.1\|622022_622361_+	hypothetical protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.9
WP_000032787.1\|622353_622590_+	hypothetical protein	A0A1P8BMT2	Lactococcus_phage	2.5e-21	66.7
WP_000573598.1\|622590_622926_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_000226353.1\|622935_623493_+\|tail	tail protein	M1PKG8	Streptococcus_phage	3.4e-64	65.8
WP_000858406.1\|623492_623738_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	9.7e-16	55.3
WP_000916437.1\|623752_624124_+	DUF5361 domain-containing protein	A0A1P8BMT6	Lactococcus_phage	9.5e-31	54.0
WP_000224695.1\|624123_626136_+	hypothetical protein	Q9F4J3	Streptococcus_phage	9.8e-13	58.9
WP_000228809.1\|626129_627662_+	hypothetical protein	J7KH53	Streptococcus_phage	4.7e-201	73.6
WP_000955554.1\|627662_631778_+	CHAP domain-containing protein	J7KBT9	Streptococcus_phage	0.0e+00	82.9
WP_000214864.1\|631790_633776_+	hypothetical protein	J7KK23	Streptococcus_phage	0.0e+00	85.2
WP_000494205.1\|633801_634131_+	DUF1366 domain-containing protein	J7KDI9	Streptococcus_phage	7.2e-22	54.3
WP_000698337.1\|634105_634318_+	hypothetical protein	J7KDP6	Streptococcus_phage	2.1e-14	60.0
WP_000215499.1\|634330_634633_+	hypothetical protein	X2KT07	Streptococcus_phage	2.2e-25	59.6
WP_001001961.1\|634634_634970_+\|holin	phage holin	A0A1P8VVK6	Streptococcus_phage	3.6e-37	72.1
WP_000236382.1\|634971_635691_+	CHAP domain-containing protein	A0A1U9WRD0	Streptococcus_virus	7.2e-59	70.3
WP_000965654.1\|636601_636781_+	hypothetical protein	J7KBZ4	Streptococcus_phage	3.6e-20	81.4
WP_079218646.1\|636880_637495_-\|integrase	site-specific integrase	F8HGP4	Streptococcus_phage	9.2e-55	60.7
WP_001881173.1\|637497_637764_-	hypothetical protein	Q77YW7	Streptococcus_phage	7.1e-20	65.2
WP_000809083.1\|637940_638168_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001122305.1\|638329_638530_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_001865698.1\|638551_638812_+\|transposase	IS3 family transposase	A0A0C5AEA5	Paenibacillus_phage	3.4e-11	43.0
WP_001867107.1\|638937_639147_+\|transposase	transposase	A0A0C5AEA5	Paenibacillus_phage	1.4e-15	55.4
WP_000508795.1\|639319_639481_-	TM2 domain-containing protein	NA	NA	NA	NA
WP_000594360.1\|640223_641501_+	ABC transporter permease	NA	NA	NA	NA
WP_000353149.1\|641510_642167_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.2e-22	31.8
WP_000594351.1\|642166_643543_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_000699093.1\|643639_644293_+	response regulator transcription factor	W8CYM9	Bacillus_phage	8.1e-25	33.6
WP_000734169.1\|644289_645609_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.2e-05	25.9
WP_000076708.1\|646485_646686_+	CsbD family protein	J7KJ36	Streptococcus_phage	8.4e-26	97.0
WP_000027835.1\|646727_646916_+	hypothetical protein	J7KIW4	Streptococcus_phage	3.3e-16	78.2
WP_001292556.1\|647701_648979_+	group II intron reverse transcriptase/maturase	NA	NA	NA	NA
WP_017771557.1\|649028_650441_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.7e-208	76.5
WP_000078930.1\|650761_651967_+	rod shape-determining protein RodA	NA	NA	NA	NA
649045:650541	attR	NA	NA	NA	NA
WP_000564843.1\|652136_653270_+\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1277661 : 1349535

Enterobacteria_phage(16.67%)

protease,transposase,tRNA,integrase

attL 1316076:1316094|attR 1358450:1358468

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001259488.1\|1277661_1278372_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA
WP_000863783.1\|1278461_1279250_-	esterase family protein	NA	NA	NA	NA
WP_001280070.1\|1279306_1280968_-	ribonuclease J	NA	NA	NA	NA
WP_032455167.1\|1281264_1282023_-	ATP-binding cassette domain-containing protein	A0A1V0SE00	Indivirus	4.1e-12	29.3
WP_000587303.1\|1282025_1282889_-	ABC transporter permease	NA	NA	NA	NA
WP_000790854.1\|1282901_1283906_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000006720.1\|1284263_1285919_+	fibronectin/fibrinogen-binding protein	A0A1J0F9J4	Only_Syngen_Nebraska_virus	2.3e-07	41.0
WP_000005484.1\|1285972_1286692_-	acetolactate decarboxylase	NA	NA	NA	NA
WP_000140346.1\|1286705_1288388_-	acetolactate synthase AlsS	NA	NA	NA	NA
WP_000934876.1\|1288497_1289724_-	hypothetical protein	NA	NA	NA	NA
WP_001081540.1\|1289713_1290904_-	AI-2E family transporter	NA	NA	NA	NA
WP_000796045.1\|1290995_1291457_-	NUDIX hydrolase	NA	NA	NA	NA
WP_000163512.1\|1291446_1291929_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
WP_000403398.1\|1292145_1295364_+	polysaccharide lyase 8 family protein	NA	NA	NA	NA
WP_000134282.1\|1295415_1296462_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.9e-68	43.6
WP_000139163.1\|1296668_1297262_-	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	NA	NA	NA	NA
WP_000676114.1\|1297261_1298131_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.7e-100	62.2
WP_000716829.1\|1298189_1299293_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_000647415.1\|1299301_1300090_-	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_000365673.1\|1300079_1300763_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_000221658.1\|1300866_1301547_-	DnaD domain-containing protein	Q938N2	Temperate_phage	1.9e-08	31.8
WP_000365343.1\|1301664_1302183_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	4.6e-31	44.1
WP_001247526.1\|1302305_1304870_-	hypothetical protein	NA	NA	NA	NA
WP_000622242.1\|1305021_1307220_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-72	28.9
WP_000124588.1\|1307216_1307978_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000405386.1\|1307979_1308909_-	ribonuclease Z	NA	NA	NA	NA
WP_000568323.1\|1308950_1309598_-	cystathionine beta-lyase	NA	NA	NA	NA
WP_000573350.1\|1309590_1310829_-	GTPase HflX	NA	NA	NA	NA
WP_001226483.1\|1310919_1311810_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_000239229.1\|1311920_1312097_+	DUF3042 family protein	NA	NA	NA	NA
WP_079394732.1\|1312138_1314328_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	2.0e-208	76.5
WP_000800371.1\|1314285_1314648_-	hypothetical protein	NA	NA	NA	NA
WP_000823040.1\|1314782_1318541_-	pullulanase	NA	NA	NA	NA
1316076:1316094	attL	NA	NA	NA	NA
WP_001205494.1\|1318709_1319444_-	hypothetical protein	NA	NA	NA	NA
WP_000130593.1\|1319458_1320043_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_000150956.1\|1320139_1321546_-	dipeptidase PepV	NA	NA	NA	NA
WP_000670189.1\|1321592_1322195_-	NAD(P)H nitroreductase	NA	NA	NA	NA
WP_000942620.1\|1322364_1324146_+	glycerophosphodiester phosphodiesterase	I6XE30	Staphylococcus_phage	9.3e-07	25.0
WP_001003953.1\|1324187_1325969_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_000567585.1\|1326127_1326895_+	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_000285046.1\|1326953_1328294_-	MATE family efflux transporter	NA	NA	NA	NA
WP_000245056.1\|1328393_1328810_-	VOC family protein	NA	NA	NA	NA
WP_000582587.1\|1328813_1329311_-	hypothetical protein	NA	NA	NA	NA
WP_000162275.1\|1329532_1330129_+	Lj965 prophage superinfection immunity protein	NA	NA	NA	NA
WP_094248916.1\|1330317_1331422_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	3.7e-70	48.9
WP_000754577.1\|1333256_1335725_-	pneumococcal-type histidine triad protein	NA	NA	NA	NA
WP_000715197.1\|1335737_1336658_-	metal ABC transporter substrate-binding lipoprotein/laminin-binding adhesin Lmb	NA	NA	NA	NA
WP_000564846.1\|1336835_1337969_-\|transposase	ISAs1-like element IS1548 family transposase	NA	NA	NA	NA
WP_001227857.1\|1338219_1341672_-	C5a peptidase ScpA/B	A0A218KC60	Bacillus_phage	7.6e-05	39.4
WP_161800227.1\|1342208_1343366_-\|transposase	ISLre2 family transposase	NA	NA	NA	NA
WP_000007459.1\|1344686_1346501_-	hypothetical protein	A0A0A7RWA3	Clostridium_phage	5.0e-32	31.9
WP_000248019.1\|1346916_1348152_+	hypothetical protein	NA	NA	NA	NA
WP_001284550.1\|1348353_1349535_-\|integrase	site-specific integrase	NA	NA	NA	NA
1358450:1358468	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1622470 : 1638196

Streptococcus_phage(86.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000767486.1\|1622470_1623298_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	1.1e-124	78.0
WP_041326615.1\|1623319_1624777_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.5
WP_000287943.1\|1624906_1625263_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.2e-42	72.6
WP_000966769.1\|1625264_1625741_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.6e-38	50.9
WP_000232154.1\|1625796_1626978_-	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	9.1e-168	75.3
WP_001198082.1\|1627039_1627588_-	GNAT family acetyltransferase	M1PSC3	Streptococcus_phage	1.4e-54	57.9
WP_000158397.1\|1627656_1628748_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	3.9e-165	78.0
WP_000603271.1\|1628880_1629516_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_001292556.1\|1630329_1631607_+	group II intron reverse transcriptase/maturase	NA	NA	NA	NA
WP_017771557.1\|1631656_1633069_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.7e-208	76.5
WP_001867099.1\|1633210_1634074_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.1e-109	70.4
WP_000358198.1\|1634079_1634406_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.2e-30	61.1
WP_000364568.1\|1634436_1635300_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	2.5e-74	50.0
WP_000715592.1\|1635319_1635955_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.8e-67	61.1
WP_001144242.1\|1636043_1636703_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	8.0e-65	56.5
WP_000178150.1\|1636721_1637432_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-18	28.5
WP_001185985.1\|1637431_1638196_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.6e-14	24.8

DBSCAN-SWA_7

1857589 : 1883871

Streptococcus_phage(85.71%)

integrase,transposase

attL 1848917:1848933|attR 1873016:1873032

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1848917:1848933	attL	NA	NA	NA	NA
WP_001291561.1\|1857589_1858807_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|1858888_1859092_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_000857133.1\|1859552_1859783_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000804885.1\|1859779_1860202_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_001240982.1\|1861001_1863920_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.1e-169	36.1
WP_000576156.1\|1863923_1864478_-	recombinase family protein	A0A0F7LA37	Escherichia_phage	2.3e-36	52.1
WP_001038790.1\|1864832_1865570_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
WP_001814874.1\|1865694_1865778_-	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_000336323.1\|1866390_1866558_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_000691736.1\|1866676_1868596_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	99.5
WP_001791010.1\|1868611_1868728_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224318.1\|1868972_1869905_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	3.1e-171	99.4
WP_000769868.1\|1869901_1870903_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	5.0e-191	100.0
WP_041326730.1\|1870899_1873077_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	99.9
1873016:1873032	attR	NA	NA	NA	NA
WP_000331160.1\|1873079_1875527_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
WP_000506270.1\|1875510_1876017_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|1875991_1876489_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|1876605_1876827_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000398284.1\|1876869_1878075_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
WP_079394735.1\|1878097_1878283_-	conjugal transfer protein	NA	NA	NA	NA
WP_000813488.1\|1878252_1879638_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|1879666_1880053_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|1880068_1880383_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_000429367.1\|1880901_1882629_-	ABC transporter permease/substrate binding protein	NA	NA	NA	NA
WP_000181801.1\|1882647_1883871_-	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.6e-29	37.0

DBSCAN-SWA_8

2168823 : 2178305

Streptococcus_phage(81.82%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000038826.1\|2168823_2169201_-	DUF1492 domain-containing protein	Q7Y4J3	Streptococcus_phage	3.2e-10	37.9
WP_000891152.1\|2169334_2169823_-	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	3.5e-49	59.3
WP_001258765.1\|2169895_2170453_-	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	2.4e-30	59.8
WP_000694573.1\|2170610_2170784_-	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	4.3e-10	56.1
WP_001069293.1\|2170780_2171038_-	hypothetical protein	NA	NA	NA	NA
WP_000656430.1\|2171330_2172725_-	hypothetical protein	W8CQP1	Croceibacter_phage	3.7e-43	33.7
WP_001029296.1\|2172736_2173594_-	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	3.0e-120	72.9
WP_001100460.1\|2173594_2173867_-	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	1.8e-18	56.8
WP_001157003.1\|2174207_2174399_-	hypothetical protein	NA	NA	NA	NA
WP_001256559.1\|2174401_2174623_-	hypothetical protein	NA	NA	NA	NA
WP_000877499.1\|2174619_2174952_-	hypothetical protein	NA	NA	NA	NA
WP_001259478.1\|2175028_2175535_-	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	4.5e-07	35.4
WP_000130289.1\|2175623_2175797_-	hypothetical protein	NA	NA	NA	NA
WP_001258609.1\|2176759_2177362_-	phage repressor protein	A0A1W6JPC3	Staphylococcus_phage	6.7e-42	46.7
WP_041326844.1\|2177377_2177563_-	hypothetical protein	A0A1X9I5U7	Streptococcus_phage	4.7e-07	56.5
WP_001080836.1\|2177717_2178305_+	helix-turn-helix domain-containing protein	A0A1X9I5U6	Streptococcus_phage	4.0e-15	37.5

DBSCAN-SWA_9

2194189 : 2206268

Streptococcus_phage(44.44%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041326845.1\|2194189_2195644_-\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.3e-208	76.5
WP_001042657.1\|2195838_2196543_-	transglycosylase SLT domain-containing protein	A0A2H4J6C5	uncultured_Caudovirales_phage	6.4e-28	65.3
WP_000029072.1\|2196648_2197188_-	LysM peptidoglycan-binding domain-containing protein	A0A249XZV3	Enterococcus_phage	3.0e-17	46.4
WP_000359357.1\|2197403_2198198_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000510606.1\|2198190_2199033_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	2.0e-15	28.5
WP_000181757.1\|2199008_2199848_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	3.5e-20	30.0
WP_000239225.1\|2199847_2200390_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_000217756.1\|2200512_2201796_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	2.2e-05	23.6
WP_000706187.1\|2201797_2203042_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	6.3e-87	41.3
WP_000384868.1\|2203280_2203634_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	9.4e-20	61.8
WP_000264865.1\|2203636_2204746_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_017771557.1\|2204855_2206268_+\|transposase	IS1182 family transposase	A0A1X9I5T2	Streptococcus_phage	1.7e-208	76.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007572

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection