CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NZ_AP014577	Burkholderia sp. RPE67 chromosome 2	2 crisprs	DEDDh,DinG,csa3,cas3,cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e	0	8	4
NZ_AP014580	Burkholderia sp. RPE67 plasmid p2, complete sequence	0 crisprs	NA	0	0	5
NZ_AP014576	Burkholderia sp. RPE67 chromosome 1	2 crisprs	cas3,DEDDh,DinG,csa3,RT,WYL	2	5	2
NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	0 crisprs	PD-DExK,csa3	0	0	0
NZ_AP014578	Burkholderia sp. RPE67 chromosome 3	0 crisprs	NA	0	0	2
NZ_AP014581	Burkholderia sp. RPE67 plasmid p3, complete sequence	0 crisprs	NA	0	0	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_AP014577_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014577_1

1739535-1740295

TypeI-E

Consensus_repeat	Method
GGTCTATCTCCGCACACGCGGAGGAACC	CRISPRCasFinder
GGTCTATCTCCGCNCACGCGGAGGAACC	CRT
GGTCTATCTCCGCACACGCGGAGGAACC	PILER-CR

12 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_AP014577_1

>merge|NZ_AP014577|1|1739535-1740295|CRISPRCasFinder,CRT,PILER-CR
GAGCTATCTCCGCGTACGCGGAGGAACCGGGCAGTCTCAGTCGCCCATTCTGAACGGCAAAGGTCTATCTCCGCGCAGGCGGAGGAACCTTGCAGCGCGTGAGCCGTTCGTCGATCTCGGTGGGTCTATCTCCGCGCGCGCGGAGGAACCCTGGAGGTGATGACGATGGAAGAGCTACACAAGGGTCTATCTCCGCCCACGCAGAGGAACCTAGACGGCTCCGTGTACCGCCCTCTGTCTTGGGAGTCTATCTCCGCACACGCGGAGGAACCATTCAAGACCTATGCCGTAGCGCGCGCAAGTGCGGTCTATCTCCGCACACGAGGAGGAACCGAATGGGTATTCGAGCAGGTACAGCTTCACGGAGGTCTATCTCCGCACGCGCGGAGGAACCACCATGCGGCGCGCGGTCCCAAGCGGCGATGCGGGTCTATCTCCGCACACGCGGAGGAACCGGCTCGACCCCGGACGCCGACTTTATGAACGACGGTCTATCTCCGCACACGCGGAGGAACCCGCTGGAGGATCGGCATGGCCAACGGCGCGCCGGGTCTATCTCCGCACACGCGGAGGAACCAGCGAAATGCTCTTTACGTGCGTGCCCAGCGTGGGTCTATCTCCGCACACGCGGAGGAACCGAAGAAGATCACGAAAGCGGGCCGTCATAAAGGGGTCTATCTCCGCACACGCGGAGGAACCGCAGCCCGCTGGCGGGCCGTATGAGGGCGTCAGGGTCTATCTCCGCACACGCGGAGGAACCC

>NZ_AP014577|1|1|1739535-1740295|CRISPRCasFinder
GAGCTATCTCCGCGTACGCGGAGGAACC	GGGCAGTCTCAGTCGCCCATTCTGAACGGCAAA
GGTCTATCTCCGCGCAGGCGGAGGAACC	TTGCAGCGCGTGAGCCGTTCGTCGATCTCGGTG
GGTCTATCTCCGCGCGCGCGGAGGAACC	CTGGAGGTGATGACGATGGAAGAGCTACACAAG
GGTCTATCTCCGCCCACGCAGAGGAACC	TAGACGGCTCCGTGTACCGCCCTCTGTCTTGGG
AGTCTATCTCCGCACACGCGGAGGAACC	ATTCAAGACCTATGCCGTAGCGCGCGCAAGTGC
GGTCTATCTCCGCACACGAGGAGGAACC	GAATGGGTATTCGAGCAGGTACAGCTTCACGGA
GGTCTATCTCCGCACGCGCGGAGGAACC	ACCATGCGGCGCGCGGTCCCAAGCGGCGATGCG
GGTCTATCTCCGCACACGCGGAGGAACC	GGCTCGACCCCGGACGCCGACTTTATGAACGAC
GGTCTATCTCCGCACACGCGGAGGAACC	CGCTGGAGGATCGGCATGGCCAACGGCGCGCCG
GGTCTATCTCCGCACACGCGGAGGAACC	AGCGAAATGCTCTTTACGTGCGTGCCCAGCGTG
GGTCTATCTCCGCACACGCGGAGGAACC	GAAGAAGATCACGAAAGCGGGCCGTCATAAAGG
GGTCTATCTCCGCACACGCGGAGGAACC	GCAGCCCGCTGGCGGGCCGTATGAGGGCGTCAG
GGTCTATCTCCGCACACGCGGAGGAACCC

>NZ_AP014577|1|1|1739535-1740294|CRT
GAGCTATCTCCGCGTACGCGGAGGAACC	GGGCAGTCTCAGTCGCCCATTCTGAACGGCAAA
GGTCTATCTCCGCGCAGGCGGAGGAACC	TTGCAGCGCGTGAGCCGTTCGTCGATCTCGGTG
GGTCTATCTCCGCGCGCGCGGAGGAACC	CTGGAGGTGATGACGATGGAAGAGCTACACAAG
GGTCTATCTCCGCCCACGCAGAGGAACC	TAGACGGCTCCGTGTACCGCCCTCTGTCTTGGG
AGTCTATCTCCGCACACGCGGAGGAACC	ATTCAAGACCTATGCCGTAGCGCGCGCAAGTGC
GGTCTATCTCCGCACACGAGGAGGAACC	GAATGGGTATTCGAGCAGGTACAGCTTCACGGA
GGTCTATCTCCGCACGCGCGGAGGAACC	ACCATGCGGCGCGCGGTCCCAAGCGGCGATGCG
GGTCTATCTCCGCACACGCGGAGGAACC	GGCTCGACCCCGGACGCCGACTTTATGAACGAC
GGTCTATCTCCGCACACGCGGAGGAACC	CGCTGGAGGATCGGCATGGCCAACGGCGCGCCG
GGTCTATCTCCGCACACGCGGAGGAACC	AGCGAAATGCTCTTTACGTGCGTGCCCAGCGTG
GGTCTATCTCCGCACACGCGGAGGAACC	GAAGAAGATCACGAAAGCGGGCCGTCATAAAGG
GGTCTATCTCCGCACACGCGGAGGAACC	GCAGCCCGCTGGCGGGCCGTATGAGGGCGTCAG
GGTCTATCTCCGCACACGCGGAGGAACC

>NZ_AP014577|1|1|1739780-1740294|PILER-CR
GTCTATCTCCGCACACGCGGAGGAACCA	TTCAAGACCTATGCCGTAGCGCGCGCAAGTGCG
GTCTATCTCCGCACACGAGGAGGAACCG	AATGGGTATTCGAGCAGGTACAGCTTCACGGAG
GTCTATCTCCGCACGCGCGGAGGAACCA	CCATGCGGCGCGCGGTCCCAAGCGGCGATGCGG
GTCTATCTCCGCACACGCGGAGGAACCG	GCTCGACCCCGGACGCCGACTTTATGAACGACG
GTCTATCTCCGCACACGCGGAGGAACCC	GCTGGAGGATCGGCATGGCCAACGGCGCGCCGG
GTCTATCTCCGCACACGCGGAGGAACCA	GCGAAATGCTCTTTACGTGCGTGCCCAGCGTGG
GTCTATCTCCGCACACGCGGAGGAACCG	AAGAAGATCACGAAAGCGGGCCGTCATAAAGGG
GTCTATCTCCGCACACGCGGAGGAACCG	CAGCCCGCTGGCGGGCCGTATGAGGGCGTCAGG
GTCTATCTCCGCACACGCGGAGGAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014577.1\|WP_045455327.1\|1726092_1728009_-\|(Fe-S)-binding-protein	unknown	unknown	gnl\|CDD\|371832
NZ_AP014577.1\|WP_014251498.1\|1728023_1730087_-\|NADH:flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240085
NZ_AP014577.1\|WP_045455358.1\|1747840_1750450_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_AP014577.1\|WP_014251501.1\|1732093_1733092_+\|GlxA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|227311
NZ_AP014577.1\|WP_045455332.1\|1735717_1736305_+\|transcriptional-regulator-BetI	unknown	unknown	gnl\|CDD\|179115
NZ_AP014577.1\|WP_045455361.1\|1750634_1752053_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|273327
NZ_AP014577.1\|WP_045455356.1\|1746239_1747844_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cls000028_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_AP014577.1\|WP_045455339.1\|1741779_1742082_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
NZ_AP014577.1\|WP_045452224.1\|1740375_1741413_-\|IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_AP014577.1\|WP_045455335.1\|1736333_1737803_+\|betaine-aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|183918
NZ_AP014577.1\|WP_045455350.1\|1744442_1745624_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_AP014577.1\|WP_045455353.1\|1745674_1746253_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0196_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_AP014577.1\|WP_014251503.1\|1734305_1735502_-\|formaldehyde-dehydrogenase,-glutathione-independent	unknown	unknown	gnl\|CDD\|274314
NZ_AP014577.1\|WP_052485718.1\|1733736_1734267_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_AP014577.1\|WP_045455342.1\|1742053_1742941_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_AP014577.1\|WP_045455347.1\|1743700_1744441_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|273842
NZ_AP014577.1\|WP_045455330.1\|1730116_1730647_-\|4-vinyl-reductase	unknown	unknown	gnl\|CDD\|198057
NZ_AP014577.1\|WP_045455337.1\|1737814_1739518_+\|choline-dehydrogenase	unknown	unknown	gnl\|CDD\|235000
NZ_AP014577.1\|WP_014251500.1\|1730683_1731655_-\|dipeptidase	unknown	unknown	gnl\|CDD\|366534
NZ_AP014577.1\|WP_045455345.1\|1742957_1743704_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09727_cas6e_CAS-I-E	gnl\|CDD\|378050

Protein	Function_ID	Function_description	E-value
NZ_AP014577.1\|WP_045455327.1\|1726092_1728009_-\|(Fe-S)-binding-protein	gnl\|CDD\|371832	pfam11982, DUF3483, Domain of unknown function (DUF3483). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 230 amino acids in length. This domain is found associated with pfam02754.	2.43548e-100
NZ_AP014577.1\|WP_014251498.1\|1728023_1730087_-\|NADH:flavin-oxidoreductase	gnl\|CDD\|240085	cd04734, OYE_like_3_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 3. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase. One member of this subgroup, the Sinorhizobium meliloti stachydrine utilization protein stcD, has been idenified as a putative N-methylproline demethylase.	0
NZ_AP014577.1\|WP_045455358.1\|1747840_1750450_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	8.79809e-90
NZ_AP014577.1\|WP_014251501.1\|1732093_1733092_+\|GlxA-family-transcriptional-regulator	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	1.0174e-138
NZ_AP014577.1\|WP_045455332.1\|1735717_1736305_+\|transcriptional-regulator-BetI	gnl\|CDD\|179115	PRK00767, PRK00767, transcriptional regulator BetI; Validated.	8.82024e-109
NZ_AP014577.1\|WP_045455361.1\|1750634_1752053_-\|MFS-transporter	gnl\|CDD\|273327	TIGR00895, transport_protein, benzoate transport. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.40329e-74
NZ_AP014577.1\|WP_045455356.1\|1746239_1747844_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	1.53914e-20
NZ_AP014577.1\|WP_045455339.1\|1741779_1742082_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	9.93166e-25
NZ_AP014577.1\|WP_045452224.1\|1740375_1741413_-\|IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.39659e-17
NZ_AP014577.1\|WP_045455335.1\|1736333_1737803_+\|betaine-aldehyde-dehydrogenase	gnl\|CDD\|183918	PRK13252, PRK13252, betaine aldehyde dehydrogenase; Provisional.	0
NZ_AP014577.1\|WP_045455350.1\|1744442_1745624_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	4.13694e-119
NZ_AP014577.1\|WP_045455353.1\|1745674_1746253_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	3.70965e-06
NZ_AP014577.1\|WP_014251503.1\|1734305_1735502_-\|formaldehyde-dehydrogenase,-glutathione-independent	gnl\|CDD\|274314	TIGR02819, formaldehyde_dehydrogenase_glutathione-independent, formaldehyde dehydrogenase, glutathione-independent. Members of this family represent a distinct clade within the larger family of zinc-dependent dehydrogenases of medium chain alcohols, a family that also includes the so-called glutathione-dependent formaldehyde dehydrogenase. Members of this protein family have a tightly bound NAD that can act as a true cofactor, rather than a cosubstrate in dehydrogenase reactions, in dismutase reactions for some aldehydes. The name given to this family, however, is formaldehyde dehydrogenase, glutathione-independent. [Central intermediary metabolism, One-carbon metabolism].	0
NZ_AP014577.1\|WP_052485718.1\|1733736_1734267_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.9193e-13
NZ_AP014577.1\|WP_045455342.1\|1742053_1742941_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	2.48307e-102
NZ_AP014577.1\|WP_045455347.1\|1743700_1744441_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	1.07392e-44
NZ_AP014577.1\|WP_045455330.1\|1730116_1730647_-\|4-vinyl-reductase	gnl\|CDD\|198057	smart00989, V4R, The V4R (vinyl 4 reductase) domain is a predicted small molecular binding domain, that may bind to hydrocarbons.	8.30538e-12
NZ_AP014577.1\|WP_045455337.1\|1737814_1739518_+\|choline-dehydrogenase	gnl\|CDD\|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
NZ_AP014577.1\|WP_014251500.1\|1730683_1731655_-\|dipeptidase	gnl\|CDD\|366534	pfam01244, Peptidase_M19, Membrane dipeptidase (Peptidase family M19).	8.2986e-122
NZ_AP014577.1\|WP_045455345.1\|1742957_1743704_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	3.29636e-26

>NZ_AP014577.1|WP_045455337.1|1737814_1739518_+|choline-dehydrogenase
MSVNEYDYIIVGAGSAGNVLASRLTEDADVTVLLLEAGGPDYRFDFRTQMPAALAFPLQGRRYNWAYETEPEPHMNNRRMECGRGKGLGGSSLINGMCYIRGNALDYDNWASMSGLENWSYLDCLPYFRKAETRDIGPNAYHGGDGPVHVTTSKPGNNPLFAAMVEAGVQAGYPRTEDLNGYQQEGFGPMDRTVTANGRRASTARGYLDRAKHRAGLTIVTHAVTDRVLFSGKRAIGVAYDHGGQRVTAHVRREVLVCSGAIASPQLLQRSGVGRSAWLKELEIPIVHDLPGVGENLQDHLEMYMQYECKEPVSLYPALQWWNQPAIGLEWMLNGTGVGASNQFEAGGFIRTRDDDLWPNIQYHFLPVAINYNGSNPIRMHGFQAHVGSMRSPSRGRVKLKSRDPHAHPSILFNYMADTLDWREFRDAIRITREIMRQPALARYRGRELHPSDDLKSDAELDAFVRAKAETAFHPSCSCKMGYDDMAVVDGEGRVHGMEGLRVVDASIMPQITTGNLNAPTIMLAEKIADRIRGVAGLERVSTDYFVAGGRRARAVGGGGERVGVGG
>NZ_AP014577.1|WP_045455335.1|1736333_1737803_+|betaine-aldehyde-dehydrogenase
MSAFGEQRLYIGGEYVDATSGESFDTLDPATGETLARVQQASQADIDRAVRSAREGQREWAAMTAMQRSRVLRRAVDLLRARNDELAAIETRDTGKPIAETRAVDIVTGADVIEYYAGLATAIEGAQIPLRESSFVYTRREPLGVCAGIGAWNYPIQIACWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGVPAGVFNVVQGDGRVGAMLAEHGGIEKISFTGGVETGKKVMARAGGSTLKEVTMELGGKSPLIVFDDANLERAADIAMTANFFSAGQVCTNGTRVFVERGVIDKFEALIAQRVKRIRIGAPDDPDTNFGPLVSAAQLQKVLGFIESGKREGARLVAGGARLADGVFARGQYVEPTVFADCRDDMRIVREEIFGPVMSILAFDDEDEVIARANDTEYGLAAGVVTENLSRAHRVIHRLEAGICWINTWGESPAEMPVGGYKQSGIGRENGIATLNAYTRTKSVQVELGPYQPVF
>NZ_AP014577.1|WP_045455332.1|1735717_1736305_+|transcriptional-regulator-BetI
MPKLGMREIRRAQLIDATLHTIDQSGLAGATLASVALRASTSTGIVSHYFGDKDGLLEATMRHVLRSLWQGTSRRRKAAKPDPRSKLRAVVAANFDVEQVNGPVMKTWLAFWSESMHKPELRRLQRVNTRRLYSNLCADFARALTKPAARRAASGLAALIDGLWLRGALAGEPFDTKGALRVAYEYIDLVLEARG
>NZ_AP014577.1|WP_014251503.1|1734305_1735502_-|formaldehyde-dehydrogenase,-glutathione-independent
MSSNRGVVYLGQGKVEVQSIDYPKMVDPRGRDIGHGVILRVVTTNICGSDQHMVRGRTTAEVGLVLGHEITGEVIEIGRDVETLSIGDLVSVPFNVACGRCPTCKSQHTGVCLNVNPSRAGGAYGYVDMGGWIGGQAEYVMVPYADFNLLKFPDKAQAMSKIRDLTCLSDILPTGYHGAVMAGVGPGSTVYIAGAGPVGMAAAASARLLGAACTIVGDMNEERLAHARAMGFETINLSKDATLGEQIEQLLGKPEVDCAVDCVGFEAHGHGSDSGHEAPATVLNSLMEITKAAGAIGIPGLYVTDDPGAVDAAAKKGALSIRFGLGWAKSHSFHTGQTPVMKYNRNLMQAILWDRLPIADIVNVSVVSLDEAPEGYRKFDGGAPRKFVIDPHGLLKAA
>NZ_AP014577.1|WP_052485718.1|1733736_1734267_-|GNAT-family-N-acetyltransferase
MTADYLRTALTFRLAVADDAAEIARIHVEAWQAAYRSIFPAAYLDSLSIPKRQALWTQLIARGMPRVVLAQRDEVTLGWIAWGASRDHDSKTTDAEIEAIYIDPLHWRQGAGRMLMDEAINAAASEGYREMTLWALEENARGLRFYKALGFALDGVFRTERVGGCEVCETRLRVAI
>NZ_AP014577.1|WP_014251501.1|1732093_1733092_+|GlxA-family-transcriptional-regulator
MSSDRTASLSHFAFMPLPNFTMIAFTNAIEVLRMANYLTGQPLYRWSLVSPEGGPVTASNGLSVDTGPVECVGQPDIVFVVGGIDVQRSTTPEHLSALRRFARTGSVLGSLCTGTYALARAGLLAGYACAIHWENMSALKEEFPDTRFLKELFVIDRDRVTCTGGVAPLDMMLNLIAARVGTARVTQIAEQFIVEHVRDTSAQQRMPLVARLGSANKSLFEVISLMENNIEEPLSREELARLAGMSQRQLQRLFREHLGMTPTHYYLTLRLRRARELLLQTDMSIMHITMACGFQSACHFSKSYRDAFGTAPTRERRKQVPPLASVSSVMVA
>NZ_AP014577.1|WP_014251500.1|1730683_1731655_-|dipeptidase
MSTLHDNSIIIDGLNISKFERSVFEDMRKGNVTAVNCTVSVWEDFQKTIDNIAEMKQQIREYSEILTLVRTTDDILRAKKENKTGIIFGFQNSYAFEDNLGYIEVFKELGVNVVQLCYNTQNLVGTGCYEPDGGLSGYGKEVIHEMNRVGIVVDLSHVGAKTSSDAIACSKKPVTYSHCCPSGLKDHPRNKSDDQLREIADANGFVGVTMFSPFLKKGPDATVDDYLEAIDYVINVIGEDKVGIGTDFTQGYSTEFFDWITHDKGRYRRLTNFGKVVNPEGIRTIGEFPNLTAAMEKAGWSETRIKKVMGENWMRYFGEVWNV
>NZ_AP014577.1|WP_045455330.1|1730116_1730647_-|4-vinyl-reductase
MQPQLPIDVDPQTGVWTTDALPMLYVPRHFFTNNHVAVEEALGLETYAEILYKAGYKSAYHWCDKEAEKHGISGMATFEHYLKRLSQRGWGLFDIVEADPQTSHARIHLRNSSFVLQQPGKQGKLCYMFAGWFAGAMDWVNDTAPEGAKKGPRSKSIETQCAAEGHAHCVFEVSPL
>NZ_AP014577.1|WP_014251498.1|1728023_1730087_-|NADH:flavin-oxidoreductase
MRYPNLFKPLQLNKLTLRNRIVSTAHAEVYAEPGGLPGDRYIRYYEEKAKGGVGLAVCGGSSPVSIDSPQGWWKSVNLSTDKVIDPLARLAEAMHRHGAFIMIQATHMGRRSAWHGEHWPHLMSPSGVREPVHRGNAKIIEVEEIKRIIEDFAAAAKRVKDAGMDGIEISAAHQHLIDQFWSPRTNFRTDEWGGSLENRLRFGTEVLKAVREAVGADFCVGLRMCGDEFHEDGLSHENLKEIAQAMSETGLIDYIGVIGSGADTHNTLANCMPPMALPPEPFVHLAAGIKTVTKLPIMHAQSIRDAGQAERLLANGMVDLVGMTRAQIADPHMVIKIRDGREDEIKQCVGANYCIDRQYNGLDVLCVQNAATSREETMPHVIEKTRGPKRKVVVVGAGPAGLEAARVARSRGHDVVLFEKNDYVGGQIMLAAKAPQREQMAGIVRWFDMETKRLGVDRRLGVAADDKMIMAEKPDIVVLATGGSSFTDQVPAWGVEQGLAVSSWDILSGKVEPGKNVLVYDGVSTHAGAGVADFIASRGNNVEIVTPDVKVADDTGGTTFPIFYRRLYAQGVIHTPNYWLDKVYEEDGKKIAVIRNEYTEEQEERAVDQVVIENGITPNDALYWKLKPESLNRGQIDMHTLFASQPQPSLSEELGNGRFLLFRVGDCISMHNIHSAIYDSLRLCKDF
>NZ_AP014577.1|WP_045455327.1|1726092_1728009_-|(Fe-S)-binding-protein
MNPVFVITALLWLSMAGLAFALLKRAAYWREGRATTAGAYGWANLLTIPKRYFVDLHHVVARDPYIAKTHVATAGGAILAMALVFINYGLAIYSVWLDRAIFLAAIIMFVGAMFVYKRRRAKDVPARLSHGPWDSLPLLLGSFAAGLALFTLLPASWMSGSLAVIIALLIAAGAYTMTFGAAQGGPMKHAMAGLLHLAFHPRQERFHAKTQHEHEAVPPTALKKPVLDAKEYGVGKPVEFRWNQLLSFDACVQCGKCEAACPAFASGQPLNPKKLIQDLVVGMVGGSDSQYAGSPTPGIPVGKHSGGPAKPLISQMIEADTIWSCTTCRACVQECPMLIEHVDAIVDMRRNQTLVEGDVPGKGPITLANLRETGSQNGYDIGARYDWSVDLQVQVAQPGRPVDVLLIAGEGAFDMRYQRTLRALAKVMNKAGVDYAVLGGVETDTGDTARRLGDEATFQQCASKLMNTLSQYQFRRIVTADPHVLHSLRNEYRALGGYYEVQHHTAFMAELVASGKLTPKAAAVLADKKITYHDPCYLGRYNGETEAPRKLLKTIGIKVVEMERHGMRARCCGGGGGAPLTDIPGKQRIPDIRIADAKSIGAEVVAVGCPQCTAMLEGVVGPRPEVLDVAELVAAALE
>NZ_AP014577.1|WP_045452224.1|1740375_1741413_-|IS481-family-transposase
MTQEQKVIRAKVGILELARQLGNVSQACRVMGYSRDSFYRFKELYDRGGEAALQEISHRRPLLKNRVDPQIEAAVVELALELPAYGQIRIANEVLKRHALSVSPQGVRSIWLRHDLETMSKRLRALEAKSAQEGLVLTEAQLVALERAKHEKEVHGEFESECPGYCGAQDTFYVGNLKGVGRVYQQTFVDTYSKVAFAKLYDRKTPLPAADLLNDRVVPFFDGFGIPLLRVLTDRGTEYCGNPEHHEYELYLAVEDIDHTRTKAKSPQTNGIVERLHKTMLNEFYRIAFRKKIYESIATLQTDLDAWLDQYNNEREHQGRWCYGKTPMRTFLDSLEVAKEKLIPH
>NZ_AP014577.1|WP_045455339.1|1741779_1742082_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MALVVVVTSDVADRFRGFLGSVMLEVSAGLYVAPRMNKGVRERTWSVLADWHGHEPRGSVVMVWRDLDAVLGIGISHLGAPPRELVEVDGMYVVRRMMTG
>NZ_AP014577.1|WP_045455342.1|1742053_1742941_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MLKGRLGLDTSRVPHADRHGLLWLERGTLNVIDGCLSFASGQHVDQIPHQSVSMILLGPGSSVTHDALRLLARHGTLLAAVGVDGVRTYTAPPLMADRSDVARRQAELWGNARRRLSVARHMYALRLGEVLPHRDLDTLRGIEGARVKMIYRLRAEQFGIDWEGRRYDRANPDAADLPNQAINHAATAVQAAAAIAVQALAAIPQLGFIHEDSGQAFVLDIADLFRDDVTLSIAFAAVKEAQRCERPIDRLVRREAAQVFRKKAVIPAMIDRVKQVLRVDEKREAGDGAGRRGDE
>NZ_AP014577.1|WP_045455345.1|1742957_1743704_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MTTLNLIHCEPDLRRLVSWAARQDWIPPGGDIGYALHAALGRAFGDRAPKPFYYRDERSGLLAYSSSSADELREAASLASPDIAALLGLDAVRGGGGLSIREFPARWTKGRVLGFEVRVCPVVRDKEGHQHDAYRAALDRAEDKAEVKREPVYGEWLARQFTATNAASIIESRMMRFQLTTSVRRTKAAAGSTDKRIACHVGGPDAVFRGHLCVEDPQAFTSLLVRGVGRHRAFGFGMLQLRPASIAT
>NZ_AP014577.1|WP_045455347.1|1743700_1744441_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MRRHLLMRLRAPLVAFGGEAIDNYGVIRDFPALSMLTGLIGNALGWDRSDFALLDGLQARLVMGTRLDNGGERLADFQTAQIGASDGGWTTLGEPEKRRGGDDSYKSPHLRYRDYHARLDALVALRLEPADEEPTLDHIAHALDHPKRPLFIGRKPCLPSARLVVGMVDASDVLDALQRAPSRDEREFRFQWPRKEGTLKNARALDICDERNWKTGVHGGWRAVLEGTGPHIAPCASLSTLPELPA
>NZ_AP014577.1|WP_045455350.1|1744442_1745624_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MPQARFIQIHTLQSYPAALLNRDDAGLAKRLPMGDAIRTRISSQCLKRHWRVADDHHSLASLDVPMAIRSRITLKLIRDELMRQNVSEALAQAAAEALRHEGLLDKAGKDLKGKEALETGQAVLLGKAEIDYLVARCAALSRDYKDETALKAAIKTFLKDEKSNIEALKHGSGLESALFGRMVTSDVLASRDAAVYVAHAFTVHEAQVENDYFTVVDDLLRETGERGSAGIFDTELASGLYYGYVVVDVPQLVANLEGIGVRECFDAPAERRALAGEVVHNLLHLIATVSPGAKRGSTAPFGHASLMLVETGDWQPRTLAGAFETALSMEPGTNVRKKAIDTLADELQKHDAAYGAPPARRFMSLDDANMPGAERVSLAELGKWTQARIVEGA
>NZ_AP014577.1|WP_045455353.1|1745674_1746253_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTSVEDTALGSRRNFYAQIGAITGFIKAGKENEGSLKADCVALARLDPNAQTLTVQQIAALTRALQRAKVECDRFSLKQWRRWGLIAHGIALSVHCSPDEAAPRLGQQLQLAGVSEARVTRLLNARGEALFQNLPRVVRLMASRNVAPNWIELGTLILNEGAVDSLRKRIAERTRIAIVRDYARARLQSERK
>NZ_AP014577.1|WP_045455356.1|1746239_1747844_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MTLQFNLLDDRLFRYRSVDDHSHDASLPELLVALARDAVRDFPALRPHQRHPWHAFLVCLAAIALREAKRDELWDTSEDWRHALLALTPDHPDGAAFSLVTPDDRPAFLQAPCKSGETRAWKKRLLTPDAVDMLITSKNHDMKAARMIHADPEDWVYALVSLQTQEGFLGAGNYGISRMNGGFASRPALGVVPAGHVGKRWARDTRLLVEQHASIAKQRDLKSKGGLALVWLRPWDGTSSLSLGELDPFYIEICRRVRLAMDGTRLVALATSSKTARIAAKERNGVTGDAWTPVNIAEAKALSITARGFDYRLASTLAFSTDFERTLASTLLEDDGETGLYLLAQGITRGQGKTEGYHERRIPVSPRIVKALRMGRTDEIAKRATDRIAAIADVRKVLWIAMCNLLGNGDSSVSDDTKKKAGDLSRPFEHEEDARFFDDLIEQVESHNENEAHDKWIGELVDRAEKMLERAFVAGPRSAERRYRAQGGALSCFHSFMRTQKYVAQSIVGVLKRRDEARRDARLDSLEEVEHDVS
>NZ_AP014577.1|WP_045455358.1|1747840_1750450_-|CRISPR-associated-helicase/endonuclease-Cas3
MQEKEGTQHVAWGKRAREGDENAPFHPLCDHMLDVAACFVALTAKGGRIREAMQATAKRVLDDKDIARLAAFVFLHDFGKANSGFQAKRWRAGAPRGWPLHAGHGVEARLALELDEHLLAGLPLDEMSAWGGAAFDLLLASLGHHGRPLREPVGIDPHLWQPVFAPDGREVYNPAATLGQIGDRLRRDLPRAFEPGGESLPDLPSFVHLFAGLVQLADWLGSSKQFFPYSEPGVERTFDEALRYATEAVERIGLDVTHLRAAMRNARITFESAFSVSAPRPMQAALGDADLGPLLILESETGSGKTEAALWRFAKLFEAGKVDSLYFALPTRVAAVQVYKRVRDFVKRLWPSDAPVVVRALAGYESADDSDKIALPDYEVLWSDNPDDIVASKRWAAESPKRFLAATIAVGTIDQALLAGLSVRHAHLRHAALSRSLLVVDEVHASDTYMSELLEHLLKAHVATGGHALLLSATLGSRQRVRFQNGVHPPCIEDACDVPYPALTDGACISELGSSGPKKPVHWQTCRAIDDFTHVARIAIDAARQGARVLIVRNTVPSAIATQEAIESMVDERAWLFNVEGVATLHHSRFSRQDRPLLDEEVEARIGKKRDGMKPCIVVGTQTLEQSLDLDADLLITDICPMDVLLQRIGRLHRHKRADEERPEAFRQARVWVLIPESGSFDAYLERPRHGLGRLRNGGGVYSDLRMIEATRRLIEARGEREIPCDNRKLVEHATHPDCLDAIAAEFGPAWQALSQQLDGGKSAERVVARLHALDYDASFEALAFPGNDERVATRLGVADRLIRFDPPVRGPFGIDVREIAMRHHMLPDDLDPDAAPSDIALCHDGFEFSLGGARFTYDRFGVRKRRLA
>NZ_AP014577.1|WP_045455361.1|1750634_1752053_-|MFS-transporter
MSVAREPRASAAARLERLPFSGYHRTIFIIIAIAFFFDSVDLGTMTFVLGSIKTEFGLSTATAGLVASASFFGMVLGAAVAGLLADRFGRRPVFQWSMVLWGLASYLCSTAQSVDALIFYRVLLGIGMGMEFPIAQTLLSEFVPTASRGRLIALMDGFWPLGFIASGVVSYFVLPTFGWRTEFALLAIPAVFVLIVRRVVPESPRWLEHRGRIDEADRVLADVEVRVMKAKGLSRLPAPSMLAEPAAKHGSGAFREIWSAAYRRRTVMVWTLWFFALLGFYGLTSWLGALMQQAGFAVTKSVLYTVLISLGGVPGFLCAAWLVERWGRKPTCIASLVGSGVMAYVYGQTALHAETPTLLICAGLAMQFFLFAMWAVLYTYTPELYGTGARATGSGFASAIGRVGSLIGPYVVGVVLPIFGQGGVFSLGAACFVVAASAVWVLGIETKGLTLETLVSEAEEQEGSGVLASARE

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Crispr_ID: NZ_AP014577_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014577_2

1741540-1741689

TypeI-E

Consensus_repeat	Method
CGGGTCTATCTCCGCACACGCGGAGGAACC	PILER-CR
GGTCTATCTCCGCACACGCGGAGGAACC	CRISPRCasFinder

2 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of NZ_AP014577_2

>merge|NZ_AP014577|2|1741540-1741689|PILER-CR,CRISPRCasFinder
GGTCTATCTCCGCACACGCGGAGGAACCGTCACGCGCTTGTCGAGCTGCGCAATGTGATCGGGTCTATCTCCGCACACGCGGAGGAACCCCGCCGCCGGCCTGCACGGAACTACTCTTCGCGGGTCTATCTCCGCACACGCGGAGGAACC

>NZ_AP014577|2|2|1741540-1741689|PILER-CR
GGTCTATCTCCGCACACGCGGAGGAACCGT	CACGCGCTTGTCGAGCTGCGCAATGTGATCG
GGTCTATCTCCGCACACGCGGAGGAACCCC	GCCGCCGGCCTGCACGGAACTACTCTTCGCG
GGTCTATCTCCGCACACGCGGAGGAACC

>NZ_AP014577|2|2|1741540-1741689|CRISPRCasFinder
GGTCTATCTCCGCACACGCGGAGGAACC	GTCACGCGCTTGTCGAGCTGCGCAATGTGATCG
GGTCTATCTCCGCACACGCGGAGGAACC	CCGCCGCCGGCCTGCACGGAACTACTCTTCGCG
GGTCTATCTCCGCACACGCGGAGGAACC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014577.1\|WP_014251516.1\|1752161_1752425_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014577.1\|WP_014251498.1\|1728023_1730087_-\|NADH:flavin-oxidoreductase	unknown	unknown	gnl\|CDD\|240085
NZ_AP014577.1\|WP_045455358.1\|1747840_1750450_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NZ_AP014577.1\|WP_014251501.1\|1732093_1733092_+\|GlxA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|227311
NZ_AP014577.1\|WP_045455332.1\|1735717_1736305_+\|transcriptional-regulator-BetI	unknown	unknown	gnl\|CDD\|179115
NZ_AP014577.1\|WP_045455361.1\|1750634_1752053_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|273327
NZ_AP014577.1\|WP_045455356.1\|1746239_1747844_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cls000028_cas8e_CAS-I-E	gnl\|CDD\|274192
NZ_AP014577.1\|WP_045455339.1\|1741779_1742082_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
NZ_AP014577.1\|WP_045452224.1\|1740375_1741413_-\|IS481-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_AP014577.1\|WP_045455335.1\|1736333_1737803_+\|betaine-aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|183918
NZ_AP014577.1\|WP_045455350.1\|1744442_1745624_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NZ_AP014577.1\|WP_045455353.1\|1745674_1746253_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	mkCas0196_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NZ_AP014577.1\|WP_014251503.1\|1734305_1735502_-\|formaldehyde-dehydrogenase,-glutathione-independent	unknown	unknown	gnl\|CDD\|274314
NZ_AP014577.1\|WP_052485718.1\|1733736_1734267_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_AP014577.1\|WP_045455342.1\|1742053_1742941_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NZ_AP014577.1\|WP_045455347.1\|1743700_1744441_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|273842
NZ_AP014577.1\|WP_045455330.1\|1730116_1730647_-\|4-vinyl-reductase	unknown	unknown	gnl\|CDD\|198057
NZ_AP014577.1\|WP_045455337.1\|1737814_1739518_+\|choline-dehydrogenase	unknown	unknown	gnl\|CDD\|235000
NZ_AP014577.1\|WP_014251500.1\|1730683_1731655_-\|dipeptidase	unknown	unknown	gnl\|CDD\|366534
NZ_AP014577.1\|WP_045455345.1\|1742957_1743704_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	cd09727_cas6e_CAS-I-E	gnl\|CDD\|378050

Protein	Function_ID	Function_description	E-value
NZ_AP014577.1\|WP_014251498.1\|1728023_1730087_-\|NADH:flavin-oxidoreductase	gnl\|CDD\|240085	cd04734, OYE_like_3_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 3. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase. One member of this subgroup, the Sinorhizobium meliloti stachydrine utilization protein stcD, has been idenified as a putative N-methylproline demethylase.	0
NZ_AP014577.1\|WP_045455358.1\|1747840_1750450_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	8.79809e-90
NZ_AP014577.1\|WP_014251501.1\|1732093_1733092_+\|GlxA-family-transcriptional-regulator	gnl\|CDD\|227311	COG4977, COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription].	1.0174e-138
NZ_AP014577.1\|WP_045455332.1\|1735717_1736305_+\|transcriptional-regulator-BetI	gnl\|CDD\|179115	PRK00767, PRK00767, transcriptional regulator BetI; Validated.	8.82024e-109
NZ_AP014577.1\|WP_045455361.1\|1750634_1752053_-\|MFS-transporter	gnl\|CDD\|273327	TIGR00895, transport_protein, benzoate transport. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.40329e-74
NZ_AP014577.1\|WP_045455356.1\|1746239_1747844_-\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|274192	TIGR02547, CRISPR_system_Cascade_subunit_CasA, CRISPR type I-E/ECOLI-associated protein CasA/Cse1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1972 from Chlorobium tepidum, is found in Ecoli subtype CRISPR/Cas regions of many bacteria, most of which are mesophiles, and not in Archaea. It is designated Cse1.	1.53914e-20
NZ_AP014577.1\|WP_045455339.1\|1741779_1742082_-\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	9.93166e-25
NZ_AP014577.1\|WP_045452224.1\|1740375_1741413_-\|IS481-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.39659e-17
NZ_AP014577.1\|WP_045455335.1\|1736333_1737803_+\|betaine-aldehyde-dehydrogenase	gnl\|CDD\|183918	PRK13252, PRK13252, betaine aldehyde dehydrogenase; Provisional.	0
NZ_AP014577.1\|WP_045455350.1\|1744442_1745624_-\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	4.13694e-119
NZ_AP014577.1\|WP_045455353.1\|1745674_1746253_-\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	3.70965e-06
NZ_AP014577.1\|WP_014251503.1\|1734305_1735502_-\|formaldehyde-dehydrogenase,-glutathione-independent	gnl\|CDD\|274314	TIGR02819, formaldehyde_dehydrogenase_glutathione-independent, formaldehyde dehydrogenase, glutathione-independent. Members of this family represent a distinct clade within the larger family of zinc-dependent dehydrogenases of medium chain alcohols, a family that also includes the so-called glutathione-dependent formaldehyde dehydrogenase. Members of this protein family have a tightly bound NAD that can act as a true cofactor, rather than a cosubstrate in dehydrogenase reactions, in dismutase reactions for some aldehydes. The name given to this family, however, is formaldehyde dehydrogenase, glutathione-independent. [Central intermediary metabolism, One-carbon metabolism].	0
NZ_AP014577.1\|WP_052485718.1\|1733736_1734267_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.9193e-13
NZ_AP014577.1\|WP_045455342.1\|1742053_1742941_-\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	2.48307e-102
NZ_AP014577.1\|WP_045455347.1\|1743700_1744441_-\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	1.07392e-44
NZ_AP014577.1\|WP_045455330.1\|1730116_1730647_-\|4-vinyl-reductase	gnl\|CDD\|198057	smart00989, V4R, The V4R (vinyl 4 reductase) domain is a predicted small molecular binding domain, that may bind to hydrocarbons.	8.30538e-12
NZ_AP014577.1\|WP_045455337.1\|1737814_1739518_+\|choline-dehydrogenase	gnl\|CDD\|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
NZ_AP014577.1\|WP_014251500.1\|1730683_1731655_-\|dipeptidase	gnl\|CDD\|366534	pfam01244, Peptidase_M19, Membrane dipeptidase (Peptidase family M19).	8.2986e-122
NZ_AP014577.1\|WP_045455345.1\|1742957_1743704_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	3.29636e-26

>NZ_AP014577.1|WP_045452224.1|1740375_1741413_-|IS481-family-transposase
MTQEQKVIRAKVGILELARQLGNVSQACRVMGYSRDSFYRFKELYDRGGEAALQEISHRRPLLKNRVDPQIEAAVVELALELPAYGQIRIANEVLKRHALSVSPQGVRSIWLRHDLETMSKRLRALEAKSAQEGLVLTEAQLVALERAKHEKEVHGEFESECPGYCGAQDTFYVGNLKGVGRVYQQTFVDTYSKVAFAKLYDRKTPLPAADLLNDRVVPFFDGFGIPLLRVLTDRGTEYCGNPEHHEYELYLAVEDIDHTRTKAKSPQTNGIVERLHKTMLNEFYRIAFRKKIYESIATLQTDLDAWLDQYNNEREHQGRWCYGKTPMRTFLDSLEVAKEKLIPH
>NZ_AP014577.1|WP_045455337.1|1737814_1739518_+|choline-dehydrogenase
MSVNEYDYIIVGAGSAGNVLASRLTEDADVTVLLLEAGGPDYRFDFRTQMPAALAFPLQGRRYNWAYETEPEPHMNNRRMECGRGKGLGGSSLINGMCYIRGNALDYDNWASMSGLENWSYLDCLPYFRKAETRDIGPNAYHGGDGPVHVTTSKPGNNPLFAAMVEAGVQAGYPRTEDLNGYQQEGFGPMDRTVTANGRRASTARGYLDRAKHRAGLTIVTHAVTDRVLFSGKRAIGVAYDHGGQRVTAHVRREVLVCSGAIASPQLLQRSGVGRSAWLKELEIPIVHDLPGVGENLQDHLEMYMQYECKEPVSLYPALQWWNQPAIGLEWMLNGTGVGASNQFEAGGFIRTRDDDLWPNIQYHFLPVAINYNGSNPIRMHGFQAHVGSMRSPSRGRVKLKSRDPHAHPSILFNYMADTLDWREFRDAIRITREIMRQPALARYRGRELHPSDDLKSDAELDAFVRAKAETAFHPSCSCKMGYDDMAVVDGEGRVHGMEGLRVVDASIMPQITTGNLNAPTIMLAEKIADRIRGVAGLERVSTDYFVAGGRRARAVGGGGERVGVGG
>NZ_AP014577.1|WP_045455335.1|1736333_1737803_+|betaine-aldehyde-dehydrogenase
MSAFGEQRLYIGGEYVDATSGESFDTLDPATGETLARVQQASQADIDRAVRSAREGQREWAAMTAMQRSRVLRRAVDLLRARNDELAAIETRDTGKPIAETRAVDIVTGADVIEYYAGLATAIEGAQIPLRESSFVYTRREPLGVCAGIGAWNYPIQIACWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGVPAGVFNVVQGDGRVGAMLAEHGGIEKISFTGGVETGKKVMARAGGSTLKEVTMELGGKSPLIVFDDANLERAADIAMTANFFSAGQVCTNGTRVFVERGVIDKFEALIAQRVKRIRIGAPDDPDTNFGPLVSAAQLQKVLGFIESGKREGARLVAGGARLADGVFARGQYVEPTVFADCRDDMRIVREEIFGPVMSILAFDDEDEVIARANDTEYGLAAGVVTENLSRAHRVIHRLEAGICWINTWGESPAEMPVGGYKQSGIGRENGIATLNAYTRTKSVQVELGPYQPVF
>NZ_AP014577.1|WP_045455332.1|1735717_1736305_+|transcriptional-regulator-BetI
MPKLGMREIRRAQLIDATLHTIDQSGLAGATLASVALRASTSTGIVSHYFGDKDGLLEATMRHVLRSLWQGTSRRRKAAKPDPRSKLRAVVAANFDVEQVNGPVMKTWLAFWSESMHKPELRRLQRVNTRRLYSNLCADFARALTKPAARRAASGLAALIDGLWLRGALAGEPFDTKGALRVAYEYIDLVLEARG
>NZ_AP014577.1|WP_014251503.1|1734305_1735502_-|formaldehyde-dehydrogenase,-glutathione-independent
MSSNRGVVYLGQGKVEVQSIDYPKMVDPRGRDIGHGVILRVVTTNICGSDQHMVRGRTTAEVGLVLGHEITGEVIEIGRDVETLSIGDLVSVPFNVACGRCPTCKSQHTGVCLNVNPSRAGGAYGYVDMGGWIGGQAEYVMVPYADFNLLKFPDKAQAMSKIRDLTCLSDILPTGYHGAVMAGVGPGSTVYIAGAGPVGMAAAASARLLGAACTIVGDMNEERLAHARAMGFETINLSKDATLGEQIEQLLGKPEVDCAVDCVGFEAHGHGSDSGHEAPATVLNSLMEITKAAGAIGIPGLYVTDDPGAVDAAAKKGALSIRFGLGWAKSHSFHTGQTPVMKYNRNLMQAILWDRLPIADIVNVSVVSLDEAPEGYRKFDGGAPRKFVIDPHGLLKAA
>NZ_AP014577.1|WP_052485718.1|1733736_1734267_-|GNAT-family-N-acetyltransferase
MTADYLRTALTFRLAVADDAAEIARIHVEAWQAAYRSIFPAAYLDSLSIPKRQALWTQLIARGMPRVVLAQRDEVTLGWIAWGASRDHDSKTTDAEIEAIYIDPLHWRQGAGRMLMDEAINAAASEGYREMTLWALEENARGLRFYKALGFALDGVFRTERVGGCEVCETRLRVAI
>NZ_AP014577.1|WP_014251501.1|1732093_1733092_+|GlxA-family-transcriptional-regulator
MSSDRTASLSHFAFMPLPNFTMIAFTNAIEVLRMANYLTGQPLYRWSLVSPEGGPVTASNGLSVDTGPVECVGQPDIVFVVGGIDVQRSTTPEHLSALRRFARTGSVLGSLCTGTYALARAGLLAGYACAIHWENMSALKEEFPDTRFLKELFVIDRDRVTCTGGVAPLDMMLNLIAARVGTARVTQIAEQFIVEHVRDTSAQQRMPLVARLGSANKSLFEVISLMENNIEEPLSREELARLAGMSQRQLQRLFREHLGMTPTHYYLTLRLRRARELLLQTDMSIMHITMACGFQSACHFSKSYRDAFGTAPTRERRKQVPPLASVSSVMVA
>NZ_AP014577.1|WP_014251500.1|1730683_1731655_-|dipeptidase
MSTLHDNSIIIDGLNISKFERSVFEDMRKGNVTAVNCTVSVWEDFQKTIDNIAEMKQQIREYSEILTLVRTTDDILRAKKENKTGIIFGFQNSYAFEDNLGYIEVFKELGVNVVQLCYNTQNLVGTGCYEPDGGLSGYGKEVIHEMNRVGIVVDLSHVGAKTSSDAIACSKKPVTYSHCCPSGLKDHPRNKSDDQLREIADANGFVGVTMFSPFLKKGPDATVDDYLEAIDYVINVIGEDKVGIGTDFTQGYSTEFFDWITHDKGRYRRLTNFGKVVNPEGIRTIGEFPNLTAAMEKAGWSETRIKKVMGENWMRYFGEVWNV
>NZ_AP014577.1|WP_045455330.1|1730116_1730647_-|4-vinyl-reductase
MQPQLPIDVDPQTGVWTTDALPMLYVPRHFFTNNHVAVEEALGLETYAEILYKAGYKSAYHWCDKEAEKHGISGMATFEHYLKRLSQRGWGLFDIVEADPQTSHARIHLRNSSFVLQQPGKQGKLCYMFAGWFAGAMDWVNDTAPEGAKKGPRSKSIETQCAAEGHAHCVFEVSPL
>NZ_AP014577.1|WP_014251498.1|1728023_1730087_-|NADH:flavin-oxidoreductase
MRYPNLFKPLQLNKLTLRNRIVSTAHAEVYAEPGGLPGDRYIRYYEEKAKGGVGLAVCGGSSPVSIDSPQGWWKSVNLSTDKVIDPLARLAEAMHRHGAFIMIQATHMGRRSAWHGEHWPHLMSPSGVREPVHRGNAKIIEVEEIKRIIEDFAAAAKRVKDAGMDGIEISAAHQHLIDQFWSPRTNFRTDEWGGSLENRLRFGTEVLKAVREAVGADFCVGLRMCGDEFHEDGLSHENLKEIAQAMSETGLIDYIGVIGSGADTHNTLANCMPPMALPPEPFVHLAAGIKTVTKLPIMHAQSIRDAGQAERLLANGMVDLVGMTRAQIADPHMVIKIRDGREDEIKQCVGANYCIDRQYNGLDVLCVQNAATSREETMPHVIEKTRGPKRKVVVVGAGPAGLEAARVARSRGHDVVLFEKNDYVGGQIMLAAKAPQREQMAGIVRWFDMETKRLGVDRRLGVAADDKMIMAEKPDIVVLATGGSSFTDQVPAWGVEQGLAVSSWDILSGKVEPGKNVLVYDGVSTHAGAGVADFIASRGNNVEIVTPDVKVADDTGGTTFPIFYRRLYAQGVIHTPNYWLDKVYEEDGKKIAVIRNEYTEEQEERAVDQVVIENGITPNDALYWKLKPESLNRGQIDMHTLFASQPQPSLSEELGNGRFLLFRVGDCISMHNIHSAIYDSLRLCKDF
>NZ_AP014577.1|WP_045455339.1|1741779_1742082_-|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MALVVVVTSDVADRFRGFLGSVMLEVSAGLYVAPRMNKGVRERTWSVLADWHGHEPRGSVVMVWRDLDAVLGIGISHLGAPPRELVEVDGMYVVRRMMTG
>NZ_AP014577.1|WP_045455342.1|1742053_1742941_-|type-I-E-CRISPR-associated-endonuclease-Cas1
MLKGRLGLDTSRVPHADRHGLLWLERGTLNVIDGCLSFASGQHVDQIPHQSVSMILLGPGSSVTHDALRLLARHGTLLAAVGVDGVRTYTAPPLMADRSDVARRQAELWGNARRRLSVARHMYALRLGEVLPHRDLDTLRGIEGARVKMIYRLRAEQFGIDWEGRRYDRANPDAADLPNQAINHAATAVQAAAAIAVQALAAIPQLGFIHEDSGQAFVLDIADLFRDDVTLSIAFAAVKEAQRCERPIDRLVRREAAQVFRKKAVIPAMIDRVKQVLRVDEKREAGDGAGRRGDE
>NZ_AP014577.1|WP_045455345.1|1742957_1743704_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MTTLNLIHCEPDLRRLVSWAARQDWIPPGGDIGYALHAALGRAFGDRAPKPFYYRDERSGLLAYSSSSADELREAASLASPDIAALLGLDAVRGGGGLSIREFPARWTKGRVLGFEVRVCPVVRDKEGHQHDAYRAALDRAEDKAEVKREPVYGEWLARQFTATNAASIIESRMMRFQLTTSVRRTKAAAGSTDKRIACHVGGPDAVFRGHLCVEDPQAFTSLLVRGVGRHRAFGFGMLQLRPASIAT
>NZ_AP014577.1|WP_045455347.1|1743700_1744441_-|type-I-E-CRISPR-associated-protein-Cas5/CasD
MRRHLLMRLRAPLVAFGGEAIDNYGVIRDFPALSMLTGLIGNALGWDRSDFALLDGLQARLVMGTRLDNGGERLADFQTAQIGASDGGWTTLGEPEKRRGGDDSYKSPHLRYRDYHARLDALVALRLEPADEEPTLDHIAHALDHPKRPLFIGRKPCLPSARLVVGMVDASDVLDALQRAPSRDEREFRFQWPRKEGTLKNARALDICDERNWKTGVHGGWRAVLEGTGPHIAPCASLSTLPELPA
>NZ_AP014577.1|WP_045455350.1|1744442_1745624_-|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MPQARFIQIHTLQSYPAALLNRDDAGLAKRLPMGDAIRTRISSQCLKRHWRVADDHHSLASLDVPMAIRSRITLKLIRDELMRQNVSEALAQAAAEALRHEGLLDKAGKDLKGKEALETGQAVLLGKAEIDYLVARCAALSRDYKDETALKAAIKTFLKDEKSNIEALKHGSGLESALFGRMVTSDVLASRDAAVYVAHAFTVHEAQVENDYFTVVDDLLRETGERGSAGIFDTELASGLYYGYVVVDVPQLVANLEGIGVRECFDAPAERRALAGEVVHNLLHLIATVSPGAKRGSTAPFGHASLMLVETGDWQPRTLAGAFETALSMEPGTNVRKKAIDTLADELQKHDAAYGAPPARRFMSLDDANMPGAERVSLAELGKWTQARIVEGA
>NZ_AP014577.1|WP_045455353.1|1745674_1746253_-|type-I-E-CRISPR-associated-protein-Cse2/CasB
MTSVEDTALGSRRNFYAQIGAITGFIKAGKENEGSLKADCVALARLDPNAQTLTVQQIAALTRALQRAKVECDRFSLKQWRRWGLIAHGIALSVHCSPDEAAPRLGQQLQLAGVSEARVTRLLNARGEALFQNLPRVVRLMASRNVAPNWIELGTLILNEGAVDSLRKRIAERTRIAIVRDYARARLQSERK
>NZ_AP014577.1|WP_045455356.1|1746239_1747844_-|type-I-E-CRISPR-associated-protein-Cse1/CasA
MTLQFNLLDDRLFRYRSVDDHSHDASLPELLVALARDAVRDFPALRPHQRHPWHAFLVCLAAIALREAKRDELWDTSEDWRHALLALTPDHPDGAAFSLVTPDDRPAFLQAPCKSGETRAWKKRLLTPDAVDMLITSKNHDMKAARMIHADPEDWVYALVSLQTQEGFLGAGNYGISRMNGGFASRPALGVVPAGHVGKRWARDTRLLVEQHASIAKQRDLKSKGGLALVWLRPWDGTSSLSLGELDPFYIEICRRVRLAMDGTRLVALATSSKTARIAAKERNGVTGDAWTPVNIAEAKALSITARGFDYRLASTLAFSTDFERTLASTLLEDDGETGLYLLAQGITRGQGKTEGYHERRIPVSPRIVKALRMGRTDEIAKRATDRIAAIADVRKVLWIAMCNLLGNGDSSVSDDTKKKAGDLSRPFEHEEDARFFDDLIEQVESHNENEAHDKWIGELVDRAEKMLERAFVAGPRSAERRYRAQGGALSCFHSFMRTQKYVAQSIVGVLKRRDEARRDARLDSLEEVEHDVS
>NZ_AP014577.1|WP_045455358.1|1747840_1750450_-|CRISPR-associated-helicase/endonuclease-Cas3
MQEKEGTQHVAWGKRAREGDENAPFHPLCDHMLDVAACFVALTAKGGRIREAMQATAKRVLDDKDIARLAAFVFLHDFGKANSGFQAKRWRAGAPRGWPLHAGHGVEARLALELDEHLLAGLPLDEMSAWGGAAFDLLLASLGHHGRPLREPVGIDPHLWQPVFAPDGREVYNPAATLGQIGDRLRRDLPRAFEPGGESLPDLPSFVHLFAGLVQLADWLGSSKQFFPYSEPGVERTFDEALRYATEAVERIGLDVTHLRAAMRNARITFESAFSVSAPRPMQAALGDADLGPLLILESETGSGKTEAALWRFAKLFEAGKVDSLYFALPTRVAAVQVYKRVRDFVKRLWPSDAPVVVRALAGYESADDSDKIALPDYEVLWSDNPDDIVASKRWAAESPKRFLAATIAVGTIDQALLAGLSVRHAHLRHAALSRSLLVVDEVHASDTYMSELLEHLLKAHVATGGHALLLSATLGSRQRVRFQNGVHPPCIEDACDVPYPALTDGACISELGSSGPKKPVHWQTCRAIDDFTHVARIAIDAARQGARVLIVRNTVPSAIATQEAIESMVDERAWLFNVEGVATLHHSRFSRQDRPLLDEEVEARIGKKRDGMKPCIVVGTQTLEQSLDLDADLLITDICPMDVLLQRIGRLHRHKRADEERPEAFRQARVWVLIPESGSFDAYLERPRHGLGRLRNGGGVYSDLRMIEATRRLIEARGEREIPCDNRKLVEHATHPDCLDAIAAEFGPAWQALSQQLDGGKSAERVVARLHALDYDASFEALAFPGNDERVATRLGVADRLIRFDPPVRGPFGIDVREIAMRHHMLPDDLDPDAAPSDIALCHDGFEFSLGGARFTYDRFGVRKRRLA
>NZ_AP014577.1|WP_045455361.1|1750634_1752053_-|MFS-transporter
MSVAREPRASAAARLERLPFSGYHRTIFIIIAIAFFFDSVDLGTMTFVLGSIKTEFGLSTATAGLVASASFFGMVLGAAVAGLLADRFGRRPVFQWSMVLWGLASYLCSTAQSVDALIFYRVLLGIGMGMEFPIAQTLLSEFVPTASRGRLIALMDGFWPLGFIASGVVSYFVLPTFGWRTEFALLAIPAVFVLIVRRVVPESPRWLEHRGRIDEADRVLADVEVRVMKAKGLSRLPAPSMLAEPAAKHGSGAFREIWSAAYRRRTVMVWTLWFFALLGFYGLTSWLGALMQQAGFAVTKSVLYTVLISLGGVPGFLCAAWLVERWGRKPTCIASLVGSGVMAYVYGQTALHAETPTLLICAGLAMQFFLFAMWAVLYTYTPELYGTGARATGSGFASAIGRVGSLIGPYVVGVVLPIFGQGGVFSLGAACFVVAASAVWVLGIETKGLTLETLVSEAEEQEGSGVLASARE
>NZ_AP014577.1|WP_014251516.1|1752161_1752425_-|hypothetical-protein
MNPSRDIAAQWSERACKEHDAHAALALLDRSIALKHRRIALIRYLHAQYLGAPLEARHHDYVKAIAARLSMEALTQIAATARARFDA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP014577_1	1.2\|1739624\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739624-1739656	33	NZ_CP024895	Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence	21804-21836	7	0.788
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP019459	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence	1259-1291	7	0.788
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP019459	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence	16858-16890	7	0.788
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP019459	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence	32458-32490	7	0.788
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP019461	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed4, complete sequence	8752-8784	7	0.788
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP019462	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed5, complete sequence	8742-8774	7	0.788
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP019463	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed6, complete sequence	8360-8392	7	0.788
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP019464	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed7, complete sequence	11509-11541	7	0.788
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP019459	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence	1259-1291	7	0.788
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP019459	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence	16858-16890	7	0.788
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP019459	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence	32458-32490	7	0.788
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP019461	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed4, complete sequence	8752-8784	7	0.788
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP019462	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed5, complete sequence	8742-8774	7	0.788
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP019463	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed6, complete sequence	8360-8392	7	0.788
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP019464	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed7, complete sequence	11509-11541	7	0.788
NZ_AP014577_2	2.1\|1741570\|31\|NZ_AP014577\|PILER-CR	1741570-1741600	31	NZ_CP015372	Pandoraea pnomenusa strain MCB032 plasmid unnamed 1, complete sequence	9711-9741	8	0.742
NZ_AP014577_2	2.1\|1741570\|31\|NZ_AP014577\|PILER-CR	1741570-1741600	31	NZ_CP015372	Pandoraea pnomenusa strain MCB032 plasmid unnamed 1, complete sequence	121048-121078	8	0.742
NZ_AP014577_2	2.1\|1741570\|31\|NZ_AP014577\|PILER-CR	1741570-1741600	31	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	10352-10382	8	0.742
NZ_AP014577_2	2.1\|1741570\|31\|NZ_AP014577\|PILER-CR	1741570-1741600	31	NC_028745	Pseudomonas phage DL60, complete genome	31360-31390	8	0.742
NZ_AP014577_2	2.2\|1741631\|31\|NZ_AP014577\|PILER-CR	1741631-1741661	31	NC_007353	Sphingomonas sp. A1 plasmid pA1 DNA, complete sequence	35782-35812	8	0.742
NZ_AP014577_2	2.2\|1741631\|31\|NZ_AP014577\|PILER-CR	1741631-1741661	31	NC_019369	Burkholderia cepacia plasmid pYS1, complete sequence	4476-4506	8	0.742
NZ_AP014577_1	1.2\|1739624\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739624-1739656	33	NZ_CP009293	Novosphingobium pentaromativorans US6-1 plasmid pLA4, complete sequence	312239-312271	9	0.727
NZ_AP014577_1	1.8\|1739990\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739990-1740022	33	MN693688	Marine virus AFVG_250M167, complete genome	27193-27225	9	0.727
NZ_AP014577_1	1.16\|1739991\|33\|NZ_AP014577\|PILER-CR	1739991-1740023	33	MN693688	Marine virus AFVG_250M167, complete genome	27193-27225	9	0.727
NZ_AP014577_2	2.2\|1741631\|31\|NZ_AP014577\|PILER-CR	1741631-1741661	31	AGRM01000006	Salmonella enterica subsp. houtenae str. ATCC BAA-1581 plasmid pSEHO0A1, complete sequence, whole genome shotgun sequence	907-937	9	0.71
NZ_AP014577_2	2.2\|1741631\|31\|NZ_AP014577\|PILER-CR	1741631-1741661	31	NZ_CP026382	Sphingopyxis sp. MG plasmid pCMS1, complete sequence	11984-12014	9	0.71
NZ_AP014577_2	2.3\|1741568\|33\|NZ_AP014577\|CRISPRCasFinder	1741568-1741600	33	NZ_CP013369	Burkholderia ubonensis strain RF23-BP41 plasmid pRF23, complete sequence	218306-218338	9	0.727
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP045330	Labrenzia sp. THAF191b plasmid pTHAF191b_b, complete sequence	27336-27368	10	0.697
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP045346	Labrenzia sp. THAF187b plasmid pTHAF187b_b, complete sequence	27336-27368	10	0.697
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP045334	Labrenzia sp. THAF191a plasmid pTHAF191a_a, complete sequence	56033-56065	10	0.697
NZ_AP014577_1	1.7\|1739929\|33\|NZ_AP014577\|CRISPRCasFinder,CRT	1739929-1739961	33	NZ_CP045382	Labrenzia sp. THAF35 plasmid pTHAF35_b, complete sequence	79627-79659	10	0.697
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP045330	Labrenzia sp. THAF191b plasmid pTHAF191b_b, complete sequence	27336-27368	10	0.697
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP045346	Labrenzia sp. THAF187b plasmid pTHAF187b_b, complete sequence	27336-27368	10	0.697
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP045334	Labrenzia sp. THAF191a plasmid pTHAF191a_a, complete sequence	56033-56065	10	0.697
NZ_AP014577_1	1.15\|1739930\|33\|NZ_AP014577\|PILER-CR	1739930-1739962	33	NZ_CP045382	Labrenzia sp. THAF35 plasmid pTHAF35_b, complete sequence	79627-79659	10	0.697

1. spacer 1.2|1739624|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP024895 (Amycolatopsis sp. AA4 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

ttgcagc----gcgtgagccgttcgtcgatctcggtg	CRISPR spacer
----agcacgggcgagagcagttcgtcgatctcggcg	Protospacer
    ***    *** **** ***************.*

2. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP019459 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

3. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP019459 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

4. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP019459 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

5. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP019461 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

6. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP019462 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

7. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP019463 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed6, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

8. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP019464 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed7, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

9. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP019459 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

10. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP019459 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

11. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP019459 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

12. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP019461 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

13. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP019462 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

14. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP019463 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed6, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

15. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP019464 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed7, complete sequence) position: , mismatch: 7, identity: 0.788

-accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
caccgag-atcgcaccgtcccaagcggcgatgcg	Protospacer
 ***. * . ***.* ******************

16. spacer 2.1|1741570|31|NZ_AP014577|PILER-CR matches to NZ_CP015372 (Pandoraea pnomenusa strain MCB032 plasmid unnamed 1, complete sequence) position: , mismatch: 8, identity: 0.742

gtcacgcgcttgtcgagctgcgcaatgtgat	CRISPR spacer
cgcacgcgctggacgagctgcgcaacttctt	Protospacer
  ******** * ************. *  *

17. spacer 2.1|1741570|31|NZ_AP014577|PILER-CR matches to NZ_CP015372 (Pandoraea pnomenusa strain MCB032 plasmid unnamed 1, complete sequence) position: , mismatch: 8, identity: 0.742

gtcacgcgcttgtcgagctgcgcaatgtgat	CRISPR spacer
cgcacgcgctggacgagctgcgcaacttctt	Protospacer
  ******** * ************. *  *

18. spacer 2.1|1741570|31|NZ_AP014577|PILER-CR matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 8, identity: 0.742

gtcacgcgcttgtcgagctgcgcaatgtgat	CRISPR spacer
gcggggtcctggtcgacctgcgcaatgtgat	Protospacer
*. . *. ** ***** **************

19. spacer 2.1|1741570|31|NZ_AP014577|PILER-CR matches to NC_028745 (Pseudomonas phage DL60, complete genome) position: , mismatch: 8, identity: 0.742

gtcacgcgcttgtcgagctgcgcaatgtgat	CRISPR spacer
gaatcgggcttgtcgagctgcgcgatgcctt	Protospacer
*   ** ****************.***.  *

20. spacer 2.2|1741631|31|NZ_AP014577|PILER-CR matches to NC_007353 (Sphingomonas sp. A1 plasmid pA1 DNA, complete sequence) position: , mismatch: 8, identity: 0.742

ccgccgccggcctgcacggaactactcttcg	CRISPR spacer
cgtgcgccggccggcaccgaactactccgag	Protospacer
*   ******** **** *********.  *

21. spacer 2.2|1741631|31|NZ_AP014577|PILER-CR matches to NC_019369 (Burkholderia cepacia plasmid pYS1, complete sequence) position: , mismatch: 8, identity: 0.742

ccgccgccggcctgcacggaactactcttcg	CRISPR spacer
cgtgcgccggccggcaccgaactactccgag	Protospacer
*   ******** **** *********.  *

22. spacer 1.2|1739624|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP009293 (Novosphingobium pentaromativorans US6-1 plasmid pLA4, complete sequence) position: , mismatch: 9, identity: 0.727

ttgcagcgcgtgagccgttcgtcgatctcggtg	CRISPR spacer
ccgtgcagcgtgagccgttcgacgacctcggtc	Protospacer
..*..  ************** ***.******

23. spacer 1.8|1739990|33|NZ_AP014577|CRISPRCasFinder,CRT matches to MN693688 (Marine virus AFVG_250M167, complete genome) position: , mismatch: 9, identity: 0.727

ggctcgaccccggacgccgactttatgaacgac	CRISPR spacer
tcctgaccctcggacgccgactttatcaacgta	Protospacer
  ** . **.**************** ****

24. spacer 1.16|1739991|33|NZ_AP014577|PILER-CR matches to MN693688 (Marine virus AFVG_250M167, complete genome) position: , mismatch: 9, identity: 0.727

ggctcgaccccggacgccgactttatgaacgac	CRISPR spacer
tcctgaccctcggacgccgactttatcaacgta	Protospacer
  ** . **.**************** ****

25. spacer 2.2|1741631|31|NZ_AP014577|PILER-CR matches to AGRM01000006 (Salmonella enterica subsp. houtenae str. ATCC BAA-1581 plasmid pSEHO0A1, complete sequence, whole genome shotgun sequence) position: , mismatch: 9, identity: 0.71

ccgccgccggcctgcacggaactactcttcg	CRISPR spacer
tgtgcgtcggcctgcaccgaactactcggag	Protospacer
.   **.********** *********   *

26. spacer 2.2|1741631|31|NZ_AP014577|PILER-CR matches to NZ_CP026382 (Sphingopyxis sp. MG plasmid pCMS1, complete sequence) position: , mismatch: 9, identity: 0.71

ccgccgccggcctgcacggaactactcttcg	CRISPR spacer
gccgcgccggcctgccccgaactactcggaa	Protospacer
 *  *********** * *********   .

27. spacer 2.3|1741568|33|NZ_AP014577|CRISPRCasFinder matches to NZ_CP013369 (Burkholderia ubonensis strain RF23-BP41 plasmid pRF23, complete sequence) position: , mismatch: 9, identity: 0.727

gtcacgcgcttgtcgagctgcgcaatgtgatcg	CRISPR spacer
tcggcgattttctcgagctgcgcaatgcgatcg	Protospacer
 . .**  .** ***************.*****

28. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP045330 (Labrenzia sp. THAF191b plasmid pTHAF191b_b, complete sequence) position: , mismatch: 10, identity: 0.697

accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
ggatcagagcgcgcgataccaagcggcgatgcg	Protospacer
.   .. .*******.* ***************

29. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP045346 (Labrenzia sp. THAF187b plasmid pTHAF187b_b, complete sequence) position: , mismatch: 10, identity: 0.697

accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
ggatcagagcgcgcgataccaagcggcgatgcg	Protospacer
.   .. .*******.* ***************

30. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP045334 (Labrenzia sp. THAF191a plasmid pTHAF191a_a, complete sequence) position: , mismatch: 10, identity: 0.697

accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
ggatcagagcgcgcgataccaagcggcgatgcg	Protospacer
.   .. .*******.* ***************

31. spacer 1.7|1739929|33|NZ_AP014577|CRISPRCasFinder,CRT matches to NZ_CP045382 (Labrenzia sp. THAF35 plasmid pTHAF35_b, complete sequence) position: , mismatch: 10, identity: 0.697

accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
ggatcagagcgcgcgataccaagcggcgatgcg	Protospacer
.   .. .*******.* ***************

32. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP045330 (Labrenzia sp. THAF191b plasmid pTHAF191b_b, complete sequence) position: , mismatch: 10, identity: 0.697

accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
ggatcagagcgcgcgataccaagcggcgatgcg	Protospacer
.   .. .*******.* ***************

33. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP045346 (Labrenzia sp. THAF187b plasmid pTHAF187b_b, complete sequence) position: , mismatch: 10, identity: 0.697

accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
ggatcagagcgcgcgataccaagcggcgatgcg	Protospacer
.   .. .*******.* ***************

34. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP045334 (Labrenzia sp. THAF191a plasmid pTHAF191a_a, complete sequence) position: , mismatch: 10, identity: 0.697

accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
ggatcagagcgcgcgataccaagcggcgatgcg	Protospacer
.   .. .*******.* ***************

35. spacer 1.15|1739930|33|NZ_AP014577|PILER-CR matches to NZ_CP045382 (Labrenzia sp. THAF35 plasmid pTHAF35_b, complete sequence) position: , mismatch: 10, identity: 0.697

accatgcggcgcgcggtcccaagcggcgatgcg	CRISPR spacer
ggatcagagcgcgcgataccaagcggcgatgcg	Protospacer
.   .. .*******.* ***************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

392710 : 424941

Mycobacterium_phage(14.29%)

protease,bacteriocin,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_175582446.1\|392710_393522_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	3.1e-18	31.2
WP_045453148.1\|393836_395141_-	MFS transporter	NA	NA	NA	NA
WP_045453150.1\|395425_396169_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_083972921.1\|396324_396906_+	amidohydrolase family protein	NA	NA	NA	NA
WP_045453152.1\|397144_397516_-	hypothetical protein	NA	NA	NA	NA
WP_045453155.1\|399096_400257_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.4e-40	37.9
WP_045455495.1\|401255_401651_+	host attachment protein	NA	NA	NA	NA
WP_045453158.1\|401904_402957_+	Dyp-type peroxidase	S4VXK8	Pandoravirus	6.7e-21	29.2
WP_045453160.1\|402949_403753_+\|bacteriocin	bacteriocin family protein	NA	NA	NA	NA
WP_045453163.1\|403901_406670_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	3.6e-122	40.0
WP_045453165.1\|406700_406916_-	hypothetical protein	NA	NA	NA	NA
WP_045455497.1\|407766_408216_-	DUF1269 domain-containing protein	NA	NA	NA	NA
WP_045453170.1\|408236_409148_-	hypothetical protein	NA	NA	NA	NA
WP_045453172.1\|409247_410255_-	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_045453175.1\|410255_411647_-	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_045453177.1\|414429_415329_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_045453179.1\|415623_417054_+	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	4.7e-17	22.8
WP_045453182.1\|417127_417505_-	TraR/DksA family transcriptional regulator	NA	NA	NA	NA
WP_175585632.1\|417946_418585_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_045455503.1\|418760_420797_+	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_014250388.1\|420874_421525_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_045452224.1\|422162_423200_-\|transposase	IS481 family transposase	E9P643	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.1e-129	64.3
WP_045451686.1\|424041_424941_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	2.7e-07	25.1

DBSCAN-SWA_2

1076928 : 1117085

Burkholderia_phage(21.05%)

integrase,portal,terminase,protease,head,plate,tail,capsid

attL 1075480:1075500|attR 1117147:1117167

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1075480:1075500	attL	NA	NA	NA	NA
WP_045454209.1\|1076928_1078116_+	acyltransferase	G9L6E5	Escherichia_phage	2.0e-29	28.7
WP_045454212.1\|1078117_1078882_-	hypothetical protein	A0A219MHL0	Dickeya_phage	2.9e-05	31.2
WP_175585637.1\|1078896_1080561_-	right-handed parallel beta-helix repeat-containing protein	NA	NA	NA	NA
WP_063774617.1\|1080749_1081013_-	hypothetical protein	I6NLI6	Burkholderia_phage	7.5e-14	51.3
WP_052485678.1\|1081065_1081275_+	hypothetical protein	NA	NA	NA	NA
WP_045454219.1\|1081244_1081724_-	glycoside hydrolase family 104 protein	D5LH07	Escherichia_phage	3.0e-53	65.6
WP_045454222.1\|1081704_1081971_-	hypothetical protein	NA	NA	NA	NA
WP_144403980.1\|1081967_1082315_-	hypothetical protein	NA	NA	NA	NA
WP_052485680.1\|1082388_1083000_-	hypothetical protein	U5P0I1	Shigella_phage	2.9e-08	40.2
WP_063774618.1\|1083013_1083679_-	DUF2313 domain-containing protein	A0A2P9JZK7	Alteromonadaceae_phage	6.3e-41	41.7
WP_045454228.1\|1083669_1084716_-\|plate	baseplate J/gp47 family protein	B5TK75	Pseudomonas_phage	4.4e-65	42.8
WP_052485681.1\|1084708_1085146_-	phage GP46 family protein	Q8HAB8	Salmonella_phage	2.2e-26	46.3
WP_052485682.1\|1085201_1085699_-\|plate	phage baseplate assembly protein	A0A192Y8K5	Salmonella_phage	6.6e-27	54.2
WP_045454231.1\|1085722_1086886_-	hypothetical protein	B5TK72	Pseudomonas_phage	1.6e-76	46.2
WP_045454233.1\|1086882_1088103_-	DNA circularization N-terminal domain-containing protein	Q8W619	Enterobacteria_phage	6.3e-47	32.1
WP_045454236.1\|1088104_1089601_-\|tail	phage tail tape measure protein	A0A2I5ARC1	Synechococcus_phage	2.5e-13	33.2
WP_045454239.1\|1089593_1089788_-	hypothetical protein	NA	NA	NA	NA
WP_045454242.1\|1089798_1090086_-\|tail	phage tail assembly protein	M1FPE4	Enterobacteria_phage	6.2e-14	48.3
WP_045454245.1\|1090082_1090442_-\|tail	phage tail tube protein	Q8W622	Enterobacteria_phage	4.1e-23	48.3
WP_045454248.1\|1090452_1091937_-\|tail	phage tail sheath subtilisin-like domain-containing protein	B5TK67	Pseudomonas_phage	1.2e-137	53.4
WP_045454251.1\|1091936_1092119_-	DUF2635 domain-containing protein	A0A2I7S9K4	Vibrio_phage	1.2e-05	54.9
WP_052485683.1\|1092128_1092749_-	hypothetical protein	Q8W624	Enterobacteria_phage	1.8e-34	42.2
WP_144404026.1\|1092745_1093105_-	hypothetical protein	Q8HAC8	Salmonella_phage	6.8e-18	44.0
WP_045454256.1\|1093182_1093527_-\|head	phage head closure protein	NA	NA	NA	NA
WP_045454259.1\|1093526_1094069_-\|head,tail	phage gp6-like head-tail connector protein	C7BGH1	Burkholderia_phage	1.9e-32	43.2
WP_175585638.1\|1094078_1094243_-	hypothetical protein	NA	NA	NA	NA
WP_045454261.1\|1094315_1095563_-\|capsid	phage major capsid protein	C7BGH0	Burkholderia_phage	7.2e-139	63.4
WP_045454263.1\|1095628_1096411_-\|protease	Clp protease ClpP	C7BGG9	Burkholderia_phage	5.2e-71	66.8
WP_045454266.1\|1096376_1097669_-\|portal	phage portal protein	C7BGG8	Burkholderia_phage	3.5e-120	50.2
WP_045454269.1\|1097665_1099366_-\|terminase	terminase large subunit	Q8W6U9	Burkholderia_virus	4.6e-306	89.5
WP_045454272.1\|1099372_1099852_-\|terminase	phage terminase small subunit P27 family	Q8W6V0	Burkholderia_virus	5.5e-63	75.9
WP_045454275.1\|1100087_1100447_-	HNH endonuclease	Q6JIE9	Burkholderia_virus	5.7e-41	66.1
WP_045454278.1\|1100573_1100867_-	hypothetical protein	A9YWZ9	Burkholderia_phage	6.8e-24	60.0
WP_144403981.1\|1101050_1101239_+	hypothetical protein	NA	NA	NA	NA
WP_144403982.1\|1101270_1101756_-	hypothetical protein	NA	NA	NA	NA
WP_045454284.1\|1101843_1102200_-	DUF2591 family protein	NA	NA	NA	NA
WP_144404027.1\|1102555_1103107_-	DUF1364 family protein	Q6JIF7	Burkholderia_virus	1.9e-19	42.4
WP_045454286.1\|1103270_1103639_-	DUF4406 domain-containing protein	H2BD42	Pseudomonas_phage	4.4e-28	54.8
WP_144403983.1\|1103635_1103995_-	hypothetical protein	NA	NA	NA	NA
WP_045454291.1\|1104042_1104618_-	hypothetical protein	Q3HQZ9	Burkholderia_phage	9.8e-59	63.2
WP_083972955.1\|1104622_1104841_-	DUF2188 domain-containing protein	NA	NA	NA	NA
WP_083972957.1\|1104837_1105923_-	helix-turn-helix domain-containing protein	Q8W6P0	Burkholderia_virus	5.2e-53	44.2
WP_144403984.1\|1105926_1106727_-	phage antirepressor KilAC domain-containing protein	A0A2K9V3K3	Faecalibacterium_phage	2.1e-35	40.9
WP_175585639.1\|1106666_1106834_-	hypothetical protein	NA	NA	NA	NA
WP_045454297.1\|1106836_1107277_-	phage regulatory CII family protein	Q6JIG6	Burkholderia_virus	4.7e-53	70.5
WP_045454300.1\|1107363_1107630_-	hypothetical protein	NA	NA	NA	NA
WP_175585640.1\|1107784_1107958_-	hypothetical protein	NA	NA	NA	NA
WP_045454303.1\|1107954_1108173_-	transcriptional regulator	NA	NA	NA	NA
WP_045454306.1\|1108267_1109008_+	LexA family transcriptional regulator	A0A1B1P9J5	Acinetobacter_phage	8.3e-26	34.3
WP_175585641.1\|1109255_1109429_+	hypothetical protein	NA	NA	NA	NA
WP_175585642.1\|1109425_1109590_+	hypothetical protein	Q3HQW6	Burkholderia_phage	1.0e-05	55.8
WP_175585643.1\|1109733_1109883_+	hypothetical protein	NA	NA	NA	NA
WP_045454309.1\|1110023_1110605_+	hypothetical protein	NA	NA	NA	NA
WP_045454311.1\|1110601_1110913_+	hypothetical protein	NA	NA	NA	NA
WP_045454314.1\|1110909_1111365_+	hypothetical protein	NA	NA	NA	NA
WP_045454317.1\|1111361_1111559_+	hypothetical protein	NA	NA	NA	NA
WP_045454319.1\|1111629_1111980_+	hypothetical protein	A0A0P0HSE1	Acinetobacter_phage	2.2e-05	33.0
WP_045454324.1\|1112163_1113435_+	DNA cytosine methyltransferase	Q6V7R9	Burkholderia_virus	1.7e-63	40.4
WP_045454327.1\|1113462_1113642_+	hypothetical protein	NA	NA	NA	NA
WP_045454330.1\|1113641_1114193_+	hypothetical protein	NA	NA	NA	NA
WP_045454332.1\|1114185_1114962_+	hypothetical protein	NA	NA	NA	NA
WP_045454334.1\|1114958_1115165_+	hypothetical protein	NA	NA	NA	NA
WP_083972959.1\|1115164_1115452_+	DUF4031 domain-containing protein	A0A0A8IK97	Aurantimonas_phage	3.0e-24	61.1
WP_144403986.1\|1115452_1115650_-	hypothetical protein	NA	NA	NA	NA
WP_045454337.1\|1115752_1115989_+	hypothetical protein	NA	NA	NA	NA
WP_045454340.1\|1115960_1117085_+\|integrase	tyrosine-type recombinase/integrase	Q9G075	Enterobacteria_phage	1.7e-54	38.2
1117147:1117167	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1157327 : 1184149

Salmonella_phage(10.53%)

tail,portal,terminase,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_045454432.1\|1157327_1157615_+	hypothetical protein	B2ZXT6	Ralstonia_phage	1.2e-09	44.9
WP_175585644.1\|1157674_1157833_-	hypothetical protein	NA	NA	NA	NA
WP_045454435.1\|1158096_1158357_-	hypothetical protein	NA	NA	NA	NA
WP_052485686.1\|1158353_1159361_-	hypothetical protein	A0A0A1I628	Burkholderia_phage	6.4e-21	46.7
WP_045454441.1\|1160495_1163822_-	host specificity protein J	A0A2R3UA88	Siphoviridae_environmental_samples	1.7e-155	41.6
WP_045454443.1\|1163818_1164376_-\|tail	tail assembly protein	M4T4A1	Cyanophage	6.4e-23	39.5
WP_045454446.1\|1164369_1165110_-	C40 family peptidase	Q8W6T2	Burkholderia_virus	7.4e-51	48.5
WP_045454448.1\|1165116_1165806_-\|tail	phage minor tail protein L	J9Q7Y5	Salmonella_phage	4.3e-61	50.0
WP_045455770.1\|1165802_1166231_-\|tail	phage tail protein	A0A0P0ZDL9	Stx2-converting_phage	7.7e-08	32.4
WP_045454451.1\|1166288_1168445_-	hypothetical protein	A0A0F7L9V3	uncultured_marine_virus	2.6e-19	31.0
WP_045454454.1\|1168661_1169018_-	hypothetical protein	NA	NA	NA	NA
WP_045454456.1\|1169042_1169990_-	hypothetical protein	NA	NA	NA	NA
WP_045454459.1\|1169986_1170346_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_045454461.1\|1170350_1170851_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_052485687.1\|1170847_1171228_-\|head	phage head closure protein	A0A1W6JP44	Morganella_phage	2.2e-06	36.2
WP_045454465.1\|1171245_1171551_-\|head,tail	phage gp6-like head-tail connector protein	B5WZS4	Pseudomonas_phage	1.6e-07	34.2
WP_083973047.1\|1171547_1172027_-	carbohydrate-binding protein	S4TNN1	Salmonella_phage	1.1e-44	55.9
WP_083973049.1\|1173015_1174428_-\|portal	phage portal protein	F8TVA0	EBPR_siphovirus	2.6e-121	55.1
WP_045454467.1\|1174487_1174880_-	hypothetical protein	NA	NA	NA	NA
WP_045454475.1\|1177045_1178869_-\|terminase	terminase large subunit	A0A0U2C138	Paracoccus_phage	1.4e-130	43.4
WP_045454477.1\|1178828_1179305_-\|terminase	phage terminase small subunit P27 family	Q6DMU4	Streptococcus_phage	2.5e-23	42.8
WP_083972971.1\|1179288_1179585_-	DNA cytosine methyltransferase	A0A2H4PAK4	Aphanizomenon_phage	6.7e-11	45.2
WP_052485689.1\|1179482_1180091_-	DNA cytosine methyltransferase	A0A1B1IRZ3	uncultured_Mediterranean_phage	1.1e-31	59.7
WP_175585645.1\|1180379_1180544_-	hypothetical protein	NA	NA	NA	NA
WP_052485691.1\|1180549_1180957_-	ParB N-terminal domain-containing protein	A0A2H4JGF1	uncultured_Caudovirales_phage	1.8e-19	52.1
WP_045454479.1\|1181076_1181373_-	HNH endonuclease	A0A2K5B276	Erysipelothrix_phage	6.0e-12	51.6
WP_052485693.1\|1181414_1181741_-	hypothetical protein	NA	NA	NA	NA
WP_144403993.1\|1181727_1182003_-	hypothetical protein	NA	NA	NA	NA
WP_045454484.1\|1182345_1183005_+	hypothetical protein	NA	NA	NA	NA
WP_045454488.1\|1183025_1183493_+	DUF488 domain-containing protein	NA	NA	NA	NA
WP_083973051.1\|1183705_1184149_+	DUF4326 domain-containing protein	A0A1S6UAA8	Serratia_phage	3.8e-18	48.4

DBSCAN-SWA_4

1709080 : 1741413

Tupanvirus(33.33%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_045455300.1\|1709080_1710034_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_045455303.1\|1710273_1711251_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_045455305.1\|1711247_1712408_-	porin	NA	NA	NA	NA
WP_045455308.1\|1712776_1714093_+	hypothetical protein	A9YVT1	Ostreococcus_tauri_virus	8.4e-05	29.5
WP_045455310.1\|1714099_1715050_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_045455312.1\|1715093_1716629_-\|holin	choline-sulfatase	A0A2K9L727	Tupanvirus	1.5e-24	26.1
WP_045455314.1\|1716735_1717647_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_045455316.1\|1717765_1718641_+	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_045452224.1\|1719357_1720395_+\|transposase	IS481 family transposase	E9P643	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.1e-129	64.3
WP_045455319.1\|1720545_1721400_-	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_144404038.1\|1721518_1722748_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	NA	NA	NA	NA
WP_014251494.1\|1722774_1724073_-	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_045455323.1\|1724169_1724928_-	drug:proton antiporter	NA	NA	NA	NA
WP_045455326.1\|1724924_1726088_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_045455327.1\|1726092_1728009_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_014251498.1\|1728023_1730087_-	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_045455330.1\|1730116_1730647_-	4-vinyl reductase	NA	NA	NA	NA
WP_014251500.1\|1730683_1731655_-	dipeptidase	NA	NA	NA	NA
WP_014251501.1\|1732093_1733092_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_052485718.1\|1733736_1734267_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014251503.1\|1734305_1735502_-	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	5.5e-11	26.2
WP_045455332.1\|1735717_1736305_+	transcriptional regulator BetI	NA	NA	NA	NA
WP_045455335.1\|1736333_1737803_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_045455337.1\|1737814_1739518_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	7.2e-49	29.1
WP_045452224.1\|1740375_1741413_-\|transposase	IS481 family transposase	E9P643	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.1e-129	64.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NZ_AP014578

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

272965 : 296270

Tupanvirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_045456471.1\|272965_274660_-	cyclic peptide export ABC transporter	G9BWD6	Planktothrix_phage	1.8e-12	26.9
WP_045456474.1\|274656_275514_-	alpha/beta hydrolase	A0A249XTU1	Mycobacterium_phage	1.4e-08	33.1
WP_045456475.1\|275720_276380_+	GAF domain-containing protein	NA	NA	NA	NA
WP_175585659.1\|276445_277444_-	hypothetical protein	NA	NA	NA	NA
WP_052485744.1\|277440_281190_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	5.9e-112	26.7
WP_083973082.1\|281215_281839_-	AMP-binding protein	A0A2K9KZV5	Tupanvirus	6.3e-11	32.1
WP_175585660.1\|281932_283291_-	AMP-binding protein	A0A2K9KZV5	Tupanvirus	1.1e-23	24.2
WP_144404044.1\|283196_296270_-	amino acid adenylation domain-containing protein	A0A2K9KZV5	Tupanvirus	3.5e-175	27.0

DBSCAN-SWA_2

1155768 : 1225766

Salmonella_phage(16.0%)

tail,capsid,head,protease,plate,terminase,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_045457861.1\|1155768_1157157_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_052485795.1\|1157175_1158003_-	type VI secretion lipoprotein TssJ	NA	NA	NA	NA
WP_045457866.1\|1158052_1158829_-	hypothetical protein	NA	NA	NA	NA
WP_014192986.1\|1158841_1159237_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_045457868.1\|1159245_1159977_-	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_045459202.1\|1159939_1160935_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_083973143.1\|1160964_1163637_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_045457872.1\|1163641_1166272_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_045457875.1\|1166354_1168997_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	3.0e-94	30.3
WP_045457877.1\|1169040_1170024_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_045457879.1\|1169987_1171712_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_167351007.1\|1171738_1172152_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_014192977.1\|1172175_1172664_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_014192976.1\|1172862_1174350_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_014192975.1\|1174351_1174846_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_175582546.1\|1175273_1175621_+	anti-sigma factor antagonist	NA	NA	NA	NA
WP_014192973.1\|1175738_1176227_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_045459206.1\|1176352_1176841_-	cache domain-containing protein	NA	NA	NA	NA
WP_045457882.1\|1177060_1177381_+	hypothetical protein	NA	NA	NA	NA
WP_045457884.1\|1177420_1178329_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_045457888.1\|1178712_1179966_+	MFS transporter	NA	NA	NA	NA
WP_045457890.1\|1180021_1180870_+	dihydroorotate dehydrogenase electron transfer subunit	NA	NA	NA	NA
WP_045457893.1\|1180862_1181813_+	dihydroorotate dehydrogenase	A0A1V0SH91	Hokovirus	8.4e-23	28.7
WP_052485796.1\|1181888_1183142_+	allantoate amidohydrolase	NA	NA	NA	NA
WP_045457898.1\|1183171_1184236_+	dihydroorotase	NA	NA	NA	NA
WP_045457900.1\|1184256_1185732_+	aspartate ammonia-lyase	NA	NA	NA	NA
WP_045457902.1\|1185763_1186450_+	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_045457904.1\|1186551_1188831_+	NADP-dependent malic enzyme	NA	NA	NA	NA
WP_045457906.1\|1188831_1189398_-	LOG family protein	NA	NA	NA	NA
WP_083973225.1\|1189394_1189970_-	flavin reductase	Q9KX93	Enterobacteria_phage	2.5e-14	42.4
WP_052485798.1\|1189918_1190500_-	cyclase family protein	NA	NA	NA	NA
WP_045457911.1\|1190596_1191382_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_045457913.1\|1191372_1192290_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_045457917.1\|1193613_1194195_+	hypothetical protein	NA	NA	NA	NA
WP_045457919.1\|1194271_1195858_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_045459212.1\|1196140_1196749_+	DNA ligase	A0A1X9SH33	Bradyrhizobium_phage	3.4e-09	29.2
WP_045457923.1\|1196913_1197204_+	hypothetical protein	NA	NA	NA	NA
WP_144404076.1\|1197246_1197543_-	hypothetical protein	NA	NA	NA	NA
WP_045457927.1\|1197628_1197835_-	hypothetical protein	NA	NA	NA	NA
WP_045457929.1\|1197922_1198444_-	hypothetical protein	NA	NA	NA	NA
WP_144404077.1\|1198470_1198905_+	hypothetical protein	NA	NA	NA	NA
WP_045459220.1\|1198922_1199111_+	superinfection immunity protein	A0A162E480	Klebsiella_phage	4.5e-05	39.1
WP_045457933.1\|1199233_1199818_+	hypothetical protein	NA	NA	NA	NA
WP_045457934.1\|1199968_1200388_+	antirestriction protein	NA	NA	NA	NA
WP_045457936.1\|1200399_1200924_+	hypothetical protein	NA	NA	NA	NA
WP_045457939.1\|1200920_1201187_+	hypothetical protein	NA	NA	NA	NA
WP_175585674.1\|1201314_1201488_-	hypothetical protein	NA	NA	NA	NA
WP_144404079.1\|1201471_1201741_-	hypothetical protein	NA	NA	NA	NA
WP_144404080.1\|1201819_1202077_+	hypothetical protein	NA	NA	NA	NA
WP_052485799.1\|1202156_1203119_-\|tail	phage tail assembly chaperone	A0A0A1I628	Burkholderia_phage	4.0e-20	46.3
WP_045457944.1\|1207581_1208139_-\|tail	tail assembly protein	A4JX15	Burkholderia_virus	1.2e-21	38.4
WP_045457946.1\|1208138_1208873_-	C40 family peptidase	D6PG99	uncultured_phage	1.9e-51	42.7
WP_144404081.1\|1208869_1209424_-	hypothetical protein	Q9MC50	Pseudomonas_phage	1.6e-26	38.5
WP_045457948.1\|1209428_1210121_-\|tail	phage minor tail protein L	J9Q7Y5	Salmonella_phage	9.7e-61	49.6
WP_045459233.1\|1210117_1210540_-\|tail	phage tail protein	A0A1B1IV54	uncultured_Mediterranean_phage	6.8e-09	38.5
WP_045457950.1\|1210588_1212706_-	hypothetical protein	A0A0U2BXT9	Paracoccus_phage	4.3e-11	32.5
WP_045457952.1\|1212715_1212901_-	hypothetical protein	NA	NA	NA	NA
WP_144404082.1\|1212897_1213248_-	hypothetical protein	NA	NA	NA	NA
WP_045457956.1\|1213262_1214198_-	hypothetical protein	NA	NA	NA	NA
WP_045457959.1\|1214194_1214551_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_052485800.1\|1214553_1215054_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_052485801.1\|1215050_1215428_-\|head	phage head closure protein	A0A1W6JP44	Morganella_phage	2.2e-06	32.1
WP_045457961.1\|1215434_1215740_-\|head,tail	phage gp6-like head-tail connector protein	B5WZS4	Pseudomonas_phage	1.1e-08	35.8
WP_175585689.1\|1215736_1216228_-	carbohydrate-binding protein	S4TNN1	Salmonella_phage	2.9e-43	53.8
WP_144404105.1\|1216868_1218329_-\|portal	phage portal protein	F8TVA0	EBPR_siphovirus	1.9e-122	54.6
WP_045457963.1\|1218331_1218610_-	hypothetical protein	NA	NA	NA	NA
WP_144404083.1\|1218678_1220085_-\|capsid	phage major capsid protein	S4TNE3	Salmonella_phage	1.5e-105	45.3
WP_144404084.1\|1220081_1220684_-\|head,protease	HK97 family phage prohead protease	S4TNE3	Salmonella_phage	2.8e-40	49.4
WP_175585675.1\|1220696_1222589_-\|terminase	terminase large subunit	A0A0U2C138	Paracoccus_phage	1.5e-119	43.1
WP_045459241.1\|1222548_1223022_-\|terminase	phage terminase small subunit P27 family	Q6DMU4	Streptococcus_phage	1.8e-18	38.1
WP_175585676.1\|1223058_1223748_-	DNA cytosine methyltransferase	A0A2H4PAK4	Aphanizomenon_phage	2.7e-15	44.6
WP_144404085.1\|1223744_1224086_-	DNA cytosine methyltransferase	A0A1B1IRZ3	uncultured_Mediterranean_phage	8.8e-07	63.4
WP_052485804.1\|1224104_1224683_-	ParB N-terminal domain-containing protein	A0A2H4JGF1	uncultured_Caudovirales_phage	2.3e-31	48.7
WP_052485805.1\|1225088_1225397_-	HNH endonuclease	U5P4L6	Shigella_phage	1.7e-12	56.1
WP_052485806.1\|1225430_1225766_-	hypothetical protein	A0A2L0E802	Propionibacterium_phage	3.5e-08	46.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NZ_AP014580

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

81305 : 96051

Mycobacterium_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_175582446.1\|81305_82116_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	3.1e-18	31.2
WP_045462609.1\|82174_83797_-	chaperonin GroEL	A0A240F779	uncultured_virus	2.4e-171	59.3
WP_045463303.1\|83904_84222_-	co-chaperone GroES	A0A221S322	uncultured_virus	4.3e-16	45.7
WP_045452224.1\|86615_87653_-\|transposase	IS481 family transposase	E9P643	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.1e-129	64.3
WP_045462612.1\|89134_89395_+	hypothetical protein	NA	NA	NA	NA
WP_045462615.1\|89404_90427_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	6.5e-37	34.0
WP_045462618.1\|91259_92513_+\|transposase	transposase	K4I413	Acidithiobacillus_phage	6.2e-98	41.2
WP_045463306.1\|92759_93797_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_045462621.1\|93895_94663_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	1.2e-72	55.0
WP_083973403.1\|94733_95096_-	response regulator	NA	NA	NA	NA
WP_175585717.1\|95239_96051_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	2.4e-18	30.9

DBSCAN-SWA_2

104850 : 173998

Bacillus_phage(22.22%)

transposase,integrase

attL 167876:167935|attR 190151:192289

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_175585588.1\|104850_105662_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	1.1e-18	31.2
WP_045463320.1\|106652_107198_+	DUF4142 domain-containing protein	NA	NA	NA	NA
WP_175585718.1\|107616_108066_+	hypothetical protein	NA	NA	NA	NA
WP_175585719.1\|108470_108995_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_045463328.1\|110411_111119_-	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_045462653.1\|112830_113292_+	hypothetical protein	NA	NA	NA	NA
WP_083973407.1\|113320_113695_-	DUF3331 domain-containing protein	NA	NA	NA	NA
WP_045463331.1\|115179_116454_-	c-type cytochrome	NA	NA	NA	NA
WP_045462659.1\|116456_116819_-	c-type cytochrome	NA	NA	NA	NA
WP_045462662.1\|116823_117762_-	cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_045462665.1\|117740_118076_-	hypothetical protein	NA	NA	NA	NA
WP_063774650.1\|118072_118717_-	cytochrome c oxidase subunit 3	NA	NA	NA	NA
WP_045462668.1\|118713_120636_-	cytochrome c oxidase subunit I	NA	NA	NA	NA
WP_045462671.1\|120632_121589_-	c-type cytochrome	NA	NA	NA	NA
WP_045462673.1\|121796_124115_+	FdhF/YdeP family oxidoreductase	NA	NA	NA	NA
WP_045463337.1\|124121_124703_-	hemerythrin domain-containing protein	NA	NA	NA	NA
WP_045462675.1\|124814_125984_-	glutathione-dependent formaldehyde dehydrogenase	NA	NA	NA	NA
WP_083973485.1\|126032_126287_-	hypothetical protein	NA	NA	NA	NA
WP_045462679.1\|126349_126664_-	hypothetical protein	NA	NA	NA	NA
WP_144404162.1\|126756_127197_-	hypothetical protein	NA	NA	NA	NA
WP_045462683.1\|128266_132424_-	PAS domain-containing protein	W8CYF6	Bacillus_phage	7.7e-20	29.5
WP_175585720.1\|132483_132936_-	response regulator	NA	NA	NA	NA
WP_045462687.1\|133361_133706_+	response regulator	NA	NA	NA	NA
WP_144404163.1\|133816_134035_+	hypothetical protein	NA	NA	NA	NA
WP_052485912.1\|134537_134789_+	hypothetical protein	NA	NA	NA	NA
WP_045462697.1\|134845_135430_-	ParB/Srx family N-terminal domain-containing protein	NA	NA	NA	NA
WP_045462700.1\|140256_140523_-	hypothetical protein	NA	NA	NA	NA
WP_045462703.1\|140651_140939_+	hypothetical protein	NA	NA	NA	NA
WP_045462706.1\|140935_143602_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	3.1e-46	29.9
WP_045462709.1\|143598_144579_-	SDR family oxidoreductase	A0A2K9KZK0	Tupanvirus	8.8e-84	47.3
WP_045462712.1\|144606_145566_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_045462715.1\|145552_146614_-	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_083973413.1\|146610_147663_-	glycosyltransferase	NA	NA	NA	NA
WP_045462718.1\|147659_149405_-	carbamoyltransferase	A0A1B1ITZ5	uncultured_Mediterranean_phage	2.9e-53	34.5
WP_045462721.1\|149407_150583_-	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_144404164.1\|150579_151149_-	HAD-IIIA family hydrolase	NA	NA	NA	NA
WP_045462728.1\|152442_153390_-	glycosyltransferase	NA	NA	NA	NA
WP_045462731.1\|153379_154084_-	PIG-L family deacetylase	NA	NA	NA	NA
WP_045463350.1\|154150_155320_-	glutathione-dependent formaldehyde dehydrogenase	NA	NA	NA	NA
WP_045462734.1\|156110_156524_-	hypothetical protein	NA	NA	NA	NA
WP_045462737.1\|156570_156825_-	DUF378 domain-containing protein	NA	NA	NA	NA
WP_045462740.1\|156899_157775_-	manganese catalase family protein	NA	NA	NA	NA
WP_045462742.1\|158085_158280_-	DUF2934 domain-containing protein	NA	NA	NA	NA
WP_052485915.1\|158326_158680_-	DUF883 domain-containing protein	NA	NA	NA	NA
WP_083973415.1\|158852_160103_+	MFS transporter	NA	NA	NA	NA
WP_083973417.1\|160200_160821_+	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_045462745.1\|161253_162237_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_045462747.1\|162312_162768_-	hypothetical protein	NA	NA	NA	NA
WP_045462749.1\|163449_163677_+	hypothetical protein	NA	NA	NA	NA
WP_045462751.1\|164274_164865_-	lipoprotein	NA	NA	NA	NA
WP_045462753.1\|165353_166529_+	porin	NA	NA	NA	NA
WP_045450427.1\|167522_169169_+\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	2.7e-16	27.7
167876:167935	attL	NA	NA	NA	NA
WP_045450426.1\|169165_169936_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	2.6e-30	34.6
WP_052485917.1\|170035_170767_+\|integrase	tyrosine-type recombinase/integrase	S5W9T9	Leptospira_phage	8.5e-15	26.0
WP_045462755.1\|170823_171822_-\|integrase	site-specific integrase	A0A1P8DJ76	Virus_Rctr85	3.0e-10	29.5
WP_045462758.1\|171818_172763_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_045462760.1\|172759_173998_-\|integrase	site-specific integrase	NA	NA	NA	NA
190151:192289	attR	NA	NA	NA	NA

DBSCAN-SWA_3

193638 : 252020

Enterobacteria_phage(16.67%)

transposase,protease,integrase

attL 188072:188131|attR 249529:251667

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
188072:188131	attL	NA	NA	NA	NA
WP_083973495.1\|193638_194424_+\|integrase	site-specific integrase	S5W9T9	Leptospira_phage	8.5e-29	31.6
WP_045462777.1\|194548_195814_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_045462779.1\|195803_196787_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_045462781.1\|196783_197794_+\|integrase	tyrosine-type recombinase/integrase	S5MBZ0	Brevibacillus_phage	4.5e-06	23.6
WP_045462784.1\|198361_199351_-\|integrase	tyrosine-type recombinase/integrase	A0A1B1IQT7	uncultured_Mediterranean_phage	2.2e-13	33.7
WP_045462959.1\|199347_200256_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_045463376.1\|200252_201101_-\|integrase	tyrosine-type recombinase/integrase	A0A1L4BKH1	Thermus_phage	3.3e-10	30.0
WP_045463383.1\|203340_204054_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_045462787.1\|204202_205084_+	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_045462790.1\|205080_205866_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_045462793.1\|205939_206212_+	hypothetical protein	NA	NA	NA	NA
WP_045463386.1\|206416_209560_-	error-prone DNA polymerase	R4TMT6	Streptomyces_phage	4.1e-90	27.1
WP_175585721.1\|209564_211049_-	DNA polymerase Y family protein	NA	NA	NA	NA
WP_045462797.1\|210972_211680_-	translesion DNA synthesis-associated protein ImuA	NA	NA	NA	NA
WP_045462800.1\|212135_212435_+	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
WP_045462803.1\|212437_213019_+	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
WP_045462806.1\|213023_214502_-	DEAD/DEAH box helicase	A0A075DXT4	Acinetobacter_phage	9.0e-64	34.3
WP_045462809.1\|214582_214921_-	hypothetical protein	NA	NA	NA	NA
WP_144404168.1\|214983_215328_-	hypothetical protein	NA	NA	NA	NA
WP_144404169.1\|215419_215878_-	hypothetical protein	NA	NA	NA	NA
WP_045463391.1\|216040_216685_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_045462815.1\|216881_217580_+	hypothetical protein	NA	NA	NA	NA
WP_045452224.1\|218531_219569_+\|transposase	IS481 family transposase	E9P643	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.1e-129	64.3
WP_014251785.1\|220376_221507_-	sensor histidine kinase	A0A1B0VMK3	Pseudomonas_phage	1.9e-58	37.2
WP_081478280.1\|221558_222053_+	response regulator	NA	NA	NA	NA
WP_041733164.1\|222570_223137_-	hypothetical protein	NA	NA	NA	NA
WP_045462821.1\|223772_224642_-\|protease	protease HtpX	NA	NA	NA	NA
WP_014251782.1\|224747_225713_-	TIM44-like domain-containing protein	NA	NA	NA	NA
WP_014251780.1\|226401_227298_+	transcriptional activator NhaR	NA	NA	NA	NA
WP_014253398.1\|228425_228698_+	hypothetical protein	NA	NA	NA	NA
WP_041733779.1\|229547_229790_+	hypothetical protein	NA	NA	NA	NA
WP_041734124.1\|229904_230111_+	hypothetical protein	NA	NA	NA	NA
WP_175582446.1\|231283_232095_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	3.1e-18	31.2
WP_144404171.1\|233022_233409_-	hypothetical protein	NA	NA	NA	NA
WP_041733617.1\|233486_233675_-	hypothetical protein	NA	NA	NA	NA
WP_041733615.1\|233836_234241_-	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_041733613.1\|234490_234955_-	DUF2934 domain-containing protein	NA	NA	NA	NA
WP_014253114.1\|235893_237207_-	cation:proton antiporter	NA	NA	NA	NA
WP_175585722.1\|240280_241588_-	hypothetical protein	NA	NA	NA	NA
WP_045463400.1\|241929_242463_-	DUF1003 domain-containing protein	NA	NA	NA	NA
WP_144404172.1\|242600_242873_-	hypothetical protein	NA	NA	NA	NA
WP_045462833.1\|242869_243637_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_083973499.1\|243603_244143_-	SRPBCC family protein	NA	NA	NA	NA
WP_144404173.1\|244467_245460_+	hypothetical protein	NA	NA	NA	NA
WP_045453155.1\|245716_246877_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.4e-40	37.9
WP_052485918.1\|247090_247552_+	hypothetical protein	NA	NA	NA	NA
WP_045462842.1\|247657_248590_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_175585723.1\|248637_249336_-	nucleoside 2-deoxyribosyltransferase	NA	NA	NA	NA
WP_045450426.1\|249606_250377_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	2.6e-30	34.6
WP_045450427.1\|250373_252020_-\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	2.7e-16	27.7
249529:251667	attR	NA	NA	NA	NA

DBSCAN-SWA_4

284674 : 402705

Gordonia_phage(12.0%)

transposase,protease,integrase

attL 303658:303717|attR 406482:406496

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_045462895.1\|284674_285907_+\|integrase	tyrosine-type recombinase/integrase	A0A166YH27	Gordonia_phage	3.5e-05	27.8
WP_045462897.1\|286013_286283_+	DUF1488 family protein	NA	NA	NA	NA
WP_175585726.1\|286742_287108_+	hypothetical protein	NA	NA	NA	NA
WP_045462900.1\|287416_287836_-	ester cyclase	NA	NA	NA	NA
WP_014253367.1\|287985_288879_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_045462904.1\|289092_290349_+	3-isopropylmalate dehydratase	NA	NA	NA	NA
WP_045462907.1\|290357_290876_+	3-isopropylmalate dehydratase	NA	NA	NA	NA
WP_045463425.1\|290893_291757_+	isocitrate lyase/PEP mutase family protein	NA	NA	NA	NA
WP_045462910.1\|292144_293002_+	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_045462913.1\|293414_294419_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_175585727.1\|294639_294777_-	hypothetical protein	NA	NA	NA	NA
WP_175585743.1\|296029_297397_+	MFS transporter	Q6JIH2	Burkholderia_virus	3.9e-45	30.8
WP_045462916.1\|297481_298711_+	CoA transferase	NA	NA	NA	NA
WP_045462919.1\|298707_299418_+	nitroreductase	NA	NA	NA	NA
WP_045462927.1\|300390_301563_+	thiolase family protein	NA	NA	NA	NA
WP_052485922.1\|301577_302996_+	MmgE/PrpD family protein	NA	NA	NA	NA
WP_175585744.1\|303345_303648_+	MFS transporter	NA	NA	NA	NA
WP_175582446.1\|303653_304465_-\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	3.1e-18	31.2
303658:303717	attL	NA	NA	NA	NA
WP_014253353.1\|306527_307433_-	LysR family transcriptional regulator	NA	NA	NA	NA
303658:303717	attL	NA	NA	NA	NA
WP_045463437.1\|307507_308503_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	9.8e-06	25.9
WP_045462938.1\|308742_309633_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_045462941.1\|309669_310473_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_045462944.1\|310486_311251_-	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	5.0e-10	27.3
WP_045462947.1\|311443_313492_-	FUSC family protein	NA	NA	NA	NA
WP_045462953.1\|314344_315823_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_045462956.1\|316101_316416_-	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_014253343.1\|316576_317437_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_045463440.1\|317546_318761_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_045463376.1\|319674_320523_+\|integrase	tyrosine-type recombinase/integrase	A0A1L4BKH1	Thermus_phage	3.3e-10	30.0
WP_045462959.1\|320519_321428_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_045462784.1\|321424_322414_+\|integrase	tyrosine-type recombinase/integrase	A0A1B1IQT7	uncultured_Mediterranean_phage	2.2e-13	33.7
WP_175585728.1\|323421_324417_-	hypothetical protein	NA	NA	NA	NA
WP_045462968.1\|326383_327625_+\|integrase	tyrosine-type recombinase/integrase	A0A166YH27	Gordonia_phage	2.7e-05	27.8
WP_175585729.1\|328650_329184_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_045462974.1\|329313_330633_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_045462977.1\|330635_331430_+	AAA family ATPase	NA	NA	NA	NA
WP_045450426.1\|332066_332837_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	2.6e-30	34.6
WP_045450427.1\|332833_334480_-\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	2.7e-16	27.7
WP_045462983.1\|335170_335875_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_175585713.1\|336651_336981_-	sensor histidine kinase	NA	NA	NA	NA
WP_063774653.1\|337447_338212_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.0e-36	42.6
WP_175582446.1\|338401_339212_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	3.1e-18	31.2
WP_045463446.1\|339209_339854_-	DUF3223 domain-containing protein	NA	NA	NA	NA
WP_045462989.1\|343066_343309_-	hypothetical protein	NA	NA	NA	NA
339150:340042	attR	NA	NA	NA	NA
WP_045463452.1\|343415_343733_-	hypothetical protein	NA	NA	NA	NA
339150:340042	attR	NA	NA	NA	NA
WP_175585730.1\|344316_344472_-	hypothetical protein	NA	NA	NA	NA
WP_045462992.1\|345130_345460_-	non-heme iron oxygenase ferredoxin subunit	NA	NA	NA	NA
WP_045462995.1\|345461_345821_-	SUF system Fe-S cluster assembly protein	NA	NA	NA	NA
WP_045462998.1\|345827_346280_-	SUF system NifU family Fe-S cluster assembly protein	A0A0P0M6T0	Mycobacterium_phage	8.1e-16	38.0
WP_045463001.1\|346276_347530_-	cysteine desulfurase	Q2XUY6	environmental_halophage	2.7e-101	43.7
WP_045463004.1\|347526_348849_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_045463007.1\|348845_349616_-	Fe-S cluster assembly ATPase SufC	A0A1M7XV31	Cedratvirus	1.5e-09	27.6
WP_045463010.1\|349648_351097_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_045463013.1\|351093_351603_-	SUF system Fe-S cluster assembly regulator	NA	NA	NA	NA
WP_045463016.1\|352348_354250_-\|protease	ATP-dependent zinc metalloprotease FtsH	M4QMW8	Micromonas_pusilla_virus	1.3e-112	41.7
WP_045463026.1\|357321_357528_-	hypothetical protein	NA	NA	NA	NA
WP_175585731.1\|357518_358577_-	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_045453155.1\|358977_360138_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.4e-40	37.9
WP_175585732.1\|360357_360522_+	hypothetical protein	NA	NA	NA	NA
WP_045463032.1\|361313_361601_+	hypothetical protein	NA	NA	NA	NA
WP_175585733.1\|361971_362241_+	hypothetical protein	NA	NA	NA	NA
WP_144404180.1\|362776_363046_-	hypothetical protein	NA	NA	NA	NA
WP_144404181.1\|363139_363358_-	hypothetical protein	NA	NA	NA	NA
WP_063774654.1\|363907_364261_-	hypothetical protein	NA	NA	NA	NA
WP_083973441.1\|364251_365112_-	transglycosylase domain-containing protein	NA	NA	NA	NA
WP_175585734.1\|366051_366630_-	hypothetical protein	NA	NA	NA	NA
WP_045463042.1\|366864_368562_+	peptidase S10	NA	NA	NA	NA
WP_052485926.1\|371990_372428_+	response regulator	NA	NA	NA	NA
WP_045451686.1\|372849_373749_-\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	2.7e-07	25.1
WP_045451689.1\|373745_374138_-	hypothetical protein	NA	NA	NA	NA
WP_175585735.1\|375208_375352_-	hypothetical protein	NA	NA	NA	NA
WP_045463048.1\|376135_376534_+	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_008345092.1\|378285_378489_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	1.8e-20	70.1
WP_144404182.1\|379027_379381_+	hypothetical protein	NA	NA	NA	NA
WP_052485927.1\|379410_379644_+	hypothetical protein	NA	NA	NA	NA
WP_045463062.1\|381450_382017_-	phasin family protein	NA	NA	NA	NA
WP_045463065.1\|382285_383353_-	PHB depolymerase family esterase	NA	NA	NA	NA
WP_045463477.1\|384401_384638_+	hypothetical protein	NA	NA	NA	NA
WP_052485928.1\|385384_385864_-	hypothetical protein	NA	NA	NA	NA
WP_045463068.1\|385869_386571_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	2.8e-39	43.3
WP_175585736.1\|386684_388208_-\|transposase	IS66 family transposase	A0A0P0ZEB3	Stx2-converting_phage	1.6e-76	36.9
WP_144404184.1\|388274_388622_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	2.1e-11	44.9
WP_175585737.1\|388615_389032_-	hypothetical protein	NA	NA	NA	NA
WP_083973445.1\|389488_389581_+\|transposase	transposase	NA	NA	NA	NA
WP_045463489.1\|389670_390144_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_045463084.1\|390143_390497_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	4.4e-17	38.3
WP_083973449.1\|391991_394070_-	recombinase family protein	A0A1B2LRQ3	Wolbachia_phage	2.4e-06	24.7
WP_083973451.1\|394056_394260_-	hypothetical protein	NA	NA	NA	NA
WP_083973453.1\|397036_397651_-	TniQ family protein	NA	NA	NA	NA
WP_045463095.1\|397655_398636_-	ATP-binding protein	NA	NA	NA	NA
WP_045463098.1\|398660_400652_-\|integrase	integrase	NA	NA	NA	NA
WP_045463101.1\|400653_401277_-	hypothetical protein	NA	NA	NA	NA
WP_045463111.1\|401517_402705_+\|integrase	tyrosine-type recombinase/integrase	A0A166YH27	Gordonia_phage	6.9e-06	28.2
406482:406496	attR	NA	NA	NA	NA

DBSCAN-SWA_5

413228 : 462822

Mycobacterium_phage(22.22%)

transposase,integrase

attL 450017:450032|attR 464729:464744

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_083973461.1\|413228_413876_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_045463512.1\|415290_415695_+	VOC family protein	NA	NA	NA	NA
WP_045453155.1\|415978_417139_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.4e-40	37.9
WP_175582446.1\|417580_418391_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	3.1e-18	31.2
WP_045463132.1\|419071_419395_-	DUF1840 domain-containing protein	NA	NA	NA	NA
WP_045463515.1\|419563_419749_+	hypothetical protein	NA	NA	NA	NA
WP_045463135.1\|420642_421068_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_045463138.1\|421611_423408_+	thiamine pyrophosphate-requiring protein	NA	NA	NA	NA
WP_045463141.1\|423425_424532_+	mandelate racemase	Q6A202	Oenococcus_phage	1.5e-15	24.2
WP_045450143.1\|424669_425776_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_045463144.1\|425884_426799_+	hypothetical protein	NA	NA	NA	NA
WP_045463147.1\|426795_427464_+	gluconate 2-dehydrogenase subunit 3 family protein	NA	NA	NA	NA
WP_045463149.1\|427453_429097_+	GMC family oxidoreductase	NA	NA	NA	NA
WP_045463152.1\|429160_430153_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_045463518.1\|430155_431937_+	glycoside hydrolase family 15 protein	NA	NA	NA	NA
WP_045463521.1\|432021_433014_+	cytochrome c oxidase subunit II	NA	NA	NA	NA
WP_045463155.1\|433010_435026_+	cytochrome c oxidase subunit I	NA	NA	NA	NA
WP_045463158.1\|435022_435637_+	heme-copper oxidase subunit III	NA	NA	NA	NA
WP_045463161.1\|435633_436077_+	hypothetical protein	NA	NA	NA	NA
WP_045463164.1\|436043_437399_+	c-type cytochrome	NA	NA	NA	NA
WP_045463167.1\|437529_438297_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	6.7e-71	54.6
WP_045463306.1\|438395_439433_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_144404197.1\|440548_440809_+	hypothetical protein	NA	NA	NA	NA
WP_045463173.1\|440985_441438_+	helix-turn-helix domain containing protein	NA	NA	NA	NA
WP_083973466.1\|441473_441728_+	hypothetical protein	NA	NA	NA	NA
WP_045463179.1\|441717_443799_+	recombinase family protein	A0A0K1Y9M7	Streptomyces_phage	1.9e-06	21.8
WP_045463531.1\|447210_448416_+	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	5.8e-45	35.8
WP_045463185.1\|448914_449622_-	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_052485943.1\|449703_449895_-	hypothetical protein	NA	NA	NA	NA
450017:450032	attL	NA	NA	NA	NA
WP_045452224.1\|451966_453004_+\|transposase	IS481 family transposase	E9P643	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	1.1e-129	64.3
WP_045463195.1\|453282_453477_-	CsbD family protein	NA	NA	NA	NA
WP_083973467.1\|453971_454169_+	hypothetical protein	NA	NA	NA	NA
WP_045463198.1\|454542_455970_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_083973511.1\|456101_456323_+	restriction endonuclease	NA	NA	NA	NA
WP_175582446.1\|456363_457174_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	3.1e-18	31.2
WP_045463205.1\|457163_457760_-	hypothetical protein	NA	NA	NA	NA
WP_175585739.1\|459013_459448_+	hypothetical protein	NA	NA	NA	NA
WP_045463207.1\|460882_461878_-\|integrase	tyrosine-type recombinase/integrase	A0A076YL28	Mesorhizobium_phage	2.3e-07	28.3
WP_045463209.1\|461874_462822_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
464729:464744	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NZ_AP014581

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

139203 : 154652

Leptospira_phage(42.86%)

integrase,transposase

attL 132338:132352|attR 151302:151316

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
132338:132352	attL	NA	NA	NA	NA
WP_045463936.1\|139203_140136_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_052485956.1\|140183_140921_-	nucleoside 2-deoxyribosyltransferase	NA	NA	NA	NA
WP_045463939.1\|141186_142884_+	Tar ligand binding domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	2.3e-07	78.0
WP_045463942.1\|142924_143368_+	response regulator	W8CYM9	Bacillus_phage	1.3e-10	37.7
WP_045463945.1\|143456_143759_-	hypothetical protein	NA	NA	NA	NA
WP_045463948.1\|144085_145219_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_175582446.1\|145367_146178_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	3.1e-18	31.2
WP_144404216.1\|146599_147349_+	hypothetical protein	NA	NA	NA	NA
WP_144404217.1\|148109_148382_+	hypothetical protein	NA	NA	NA	NA
WP_045463963.1\|148530_148959_+	DUF29 domain-containing protein	NA	NA	NA	NA
WP_045463965.1\|148986_149205_-	DUF3717 domain-containing protein	NA	NA	NA	NA
WP_175582446.1\|149793_150604_+\|transposase	IS5 family transposase	A0A0M5M147	Mycobacterium_phage	3.1e-18	31.2
WP_045463971.1\|150887_151241_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	5.7e-17	40.4
WP_045463973.1\|152187_153768_-\|transposase	IS66 family transposase	S5VTD3	Leptospira_phage	6.4e-68	34.2
151302:151316	attR	NA	NA	NA	NA
WP_045463971.1\|153798_154152_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	5.7e-17	40.4
WP_045463976.1\|154127_154652_-\|transposase	transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NZ_AP014576

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_AP014576_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014576_1

504408-505284

Orphan

Consensus_repeat	Method
GTTTCCTCCGCGTGCGCGGAGAT	CRISPRCasFinder

14 spacers

The CRISPR arrays of NZ_AP014576_1

>merge|NZ_AP014576|1|504408-505284|CRISPRCasFinder
GTTTCCTCCGTGTGGGCGGAGATAGGCCGCGTCGAGCTGTTCCGTTTTTCTTCAAGATCGGGTTTCCTCCGCGTGGGCGGAGATAGCCCGATGATGACGCCGCCGTTGCGAATCTCGACCATGTTTCCTCCGAGTACGCGGAGATAGCCCCGAGCCCGCGACCGCCGAGCGCTGGCGTTCGCTGTTTCCTCCGAGTACGCGGAGATAGACCCCGATAGTTTCGAGGCAATTGGCCGGCTCGTCGGTTTCCTCCGAGTACGCGGAGATAGACCGCACTATCAAGTCGCCGCCGACGCCATGCAAGAGTTTCCTCCGCGTGCGCGGAGATAGACCCCTCTTCGCGCGCTTTCTGAACAAGTGCACGAGGTTTCCTCCGCGTGCGCGGAGATAGACCCACCATCCGCCGCCTGCTGAATTTGTGTCTCGAGTTTCCTCCGCGTGGGCGGAGATAGGCCCGTCATCAAACGCAATGCGGATGGCTTGTACGCGTTTCCTCCGCGTGCGCGGAGATGGACCCGCCTGTGTCGCGCTGCCTTGCGCGGCTTGCGAGTTTCCTCCGCGTACGCGGAGATAGGCCCAAGCGCTGCGAGATCGCCGGCATTCGCTTCGAGTTTCCTCCGCGTACGCGGAGATAGGCCGATGACCGTCAGCACGATCATGGGTAAGGGTTCGTTTCCTCCGCGTGGGCGGAGATAGGCCGGCTTGACCGTAGTTCGCGCTCTGTGAGGACTGGTTTCCTCCGCGTGTGCGGAGATAGGCCGTTTCCGGCCCCGTTCGGCTATGGGCGCATCGCGTTTCCTCCGCGTACGCGGAGATAGGCCCCCGCGCATCGAAGTGCGCATTCGGCCGATGCAGTTTCCTCCGCATGCGGAGATAC

>NZ_AP014576|1|1|504408-505284|CRISPRCasFinder
GTTTCCTCCGTGTGGGCGGAGAT	AGGCCGCGTCGAGCTGTTCCGTTTTTCTTCAAGATCGG
GTTTCCTCCGCGTGGGCGGAGAT	AGCCCGATGATGACGCCGCCGTTGCGAATCTCGACCAT
GTTTCCTCCGAGTACGCGGAGAT	AGCCCCGAGCCCGCGACCGCCGAGCGCTGGCGTTCGCT
GTTTCCTCCGAGTACGCGGAGAT	AGACCCCGATAGTTTCGAGGCAATTGGCCGGCTCGTCG
GTTTCCTCCGAGTACGCGGAGAT	AGACCGCACTATCAAGTCGCCGCCGACGCCATGCAAGA
GTTTCCTCCGCGTGCGCGGAGAT	AGACCCCTCTTCGCGCGCTTTCTGAACAAGTGCACGAG
GTTTCCTCCGCGTGCGCGGAGAT	AGACCCACCATCCGCCGCCTGCTGAATTTGTGTCTCGA
GTTTCCTCCGCGTGGGCGGAGAT	AGGCCCGTCATCAAACGCAATGCGGATGGCTTGTACGC
GTTTCCTCCGCGTGCGCGGAGAT	GGACCCGCCTGTGTCGCGCTGCCTTGCGCGGCTTGCGA
GTTTCCTCCGCGTACGCGGAGAT	AGGCCCAAGCGCTGCGAGATCGCCGGCATTCGCTTCGA
GTTTCCTCCGCGTACGCGGAGAT	AGGCCGATGACCGTCAGCACGATCATGGGTAAGGGTTC
GTTTCCTCCGCGTGGGCGGAGAT	AGGCCGGCTTGACCGTAGTTCGCGCTCTGTGAGGACTG
GTTTCCTCCGCGTGTGCGGAGAT	AGGCCGTTTCCGGCCCCGTTCGGCTATGGGCGCATCGC
GTTTCCTCCGCGTACGCGGAGAT	AGGCCCCCGCGCATCGAAGTGCGCATTCGGCCGATGCA
GTTTCCTCCGCATGCGGAGATAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014576.1\|WP_014190551.1\|508609_509272_+\|response-regulator	unknown	unknown	gnl\|CDD\|182612
NZ_AP014576.1\|WP_014190545.1\|500607_501498_+\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl\|CDD\|237571
NZ_AP014576.1\|WP_075644198.1\|493487_494408_-\|branched-chain-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|235841
NZ_AP014576.1\|WP_045450371.1\|509271_510573_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|182388
NZ_AP014576.1\|WP_045450370.1\|506754_508350_-\|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase	unknown	unknown	gnl\|CDD\|224938
NZ_AP014576.1\|WP_045450374.1\|513212_513590_+\|DUF427-domain-containing-protein	unknown	unknown	gnl\|CDD\|377265
NZ_AP014576.1\|WP_014190554.1\|512576_513068_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372685
NZ_AP014576.1\|WP_045450364.1\|494801_495548_+\|AzlC-family-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224215
NZ_AP014576.1\|WP_045450375.1\|514464_515421_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|181818
NZ_AP014576.1\|WP_045450368.1\|503304_504327_+\|threonylcarbamoyl-AMP-synthase	unknown	unknown	gnl\|CDD\|223088
NZ_AP014576.1\|WP_014190543.1\|497771_499208_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NZ_AP014576.1\|WP_045450365.1\|496228_497425_+\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
NZ_AP014576.1\|WP_045450366.1\|501509_502022_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	unknown	unknown	gnl\|CDD\|376377
NZ_AP014576.1\|WP_045450369.1\|505415_506522_-\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238883
NZ_AP014576.1\|WP_045450367.1\|502092_503280_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NZ_AP014576.1\|WP_014190544.1\|499386_500451_+\|fructose-bisphosphate-aldolase-class-II	unknown	unknown	gnl\|CDD\|181691
NZ_AP014576.1\|WP_014190556.1\|513664_514468_+\|carbon-monoxide-dehydrogenase-subunit-G	unknown	unknown	gnl\|CDD\|176853
NZ_AP014576.1\|WP_045450376.1\|515549_516179_+\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238496
NZ_AP014576.1\|WP_014190541.1\|495544_495868_+\|AzlD-domain-containing-protein	unknown	unknown	gnl\|CDD\|377512
NZ_AP014576.1\|WP_045450373.1\|510918_512436_+\|DegQ-family-serine-endoprotease	unknown	unknown	gnl\|CDD\|273938

Protein	Function_ID	Function_description	E-value
NZ_AP014576.1\|WP_014190551.1\|508609_509272_+\|response-regulator	gnl\|CDD\|182612	PRK10643, PRK10643, two-component system response regulator PmrA.	3.5317e-83
NZ_AP014576.1\|WP_014190545.1\|500607_501498_+\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl\|CDD\|237571	PRK13961, PRK13961, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	0
NZ_AP014576.1\|WP_075644198.1\|493487_494408_-\|branched-chain-amino-acid-transaminase	gnl\|CDD\|235841	PRK06606, PRK06606, branched-chain amino acid transaminase.	0
NZ_AP014576.1\|WP_045450371.1\|509271_510573_+\|HAMP-domain-containing-protein	gnl\|CDD\|182388	PRK10337, PRK10337, sensor protein QseC; Provisional.	2.94311e-75
NZ_AP014576.1\|WP_045450370.1\|506754_508350_-\|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase	gnl\|CDD\|224938	COG2027, DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane].	4.19282e-108
NZ_AP014576.1\|WP_045450374.1\|513212_513590_+\|DUF427-domain-containing-protein	gnl\|CDD\|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	1.09545e-38
NZ_AP014576.1\|WP_014190554.1\|512576_513068_+\|hypothetical-protein	gnl\|CDD\|372685	pfam13715, CarbopepD_reg_2, CarboxypepD_reg-like domain. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.	0.00052394
NZ_AP014576.1\|WP_045450364.1\|494801_495548_+\|AzlC-family-ABC-transporter-permease	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	4.79702e-44
NZ_AP014576.1\|WP_045450375.1\|514464_515421_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	1.49936e-129
NZ_AP014576.1\|WP_045450368.1\|503304_504327_+\|threonylcarbamoyl-AMP-synthase	gnl\|CDD\|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	6.53191e-70
NZ_AP014576.1\|WP_014190543.1\|497771_499208_+\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NZ_AP014576.1\|WP_045450365.1\|496228_497425_+\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
NZ_AP014576.1\|WP_045450366.1\|501509_502022_+\|5-(carboxyamino)imidazole-ribonucleotide-mutase	gnl\|CDD\|376377	pfam00731, AIRC, AIR carboxylase. Members of this family catalyze the decarboxylation of 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR). This family catalyze the sixth step of de novo purine biosynthesis. Some members of this family contain two copies of this domain.	6.71868e-83
NZ_AP014576.1\|WP_045450369.1\|505415_506522_-\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238883	cd01847, Triacylglycerol_lipase_like, Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases. Members of this subfamily might hydrolyze triacylglycerol into diacylglycerol and fatty acid anions.	1.27034e-54
NZ_AP014576.1\|WP_045450367.1\|502092_503280_+\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	0
NZ_AP014576.1\|WP_014190544.1\|499386_500451_+\|fructose-bisphosphate-aldolase-class-II	gnl\|CDD\|181691	PRK09196, PRK09196, fructose-bisphosphate aldolase class II.	0
NZ_AP014576.1\|WP_014190556.1\|513664_514468_+\|carbon-monoxide-dehydrogenase-subunit-G	gnl\|CDD\|176853	cd05018, CoxG, Carbon monoxide dehydrogenase subunit G (CoxG). CoxG has been shown, in Oligotropha carboxidovorans, to anchor the carbon monoxide (CO) dehydrogenase to the cytoplasmic membrane. The gene encoding CoxG is part of the Cox cluster (coxBCMSLDEFGHIK) located on a low-copy-number, circular, megaplasmid pHCG3. This cluster includes genes encoding subunits of CO dehydrogenase and several accessory components involved in the utilization of CO. This family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands.	4.20639e-18
NZ_AP014576.1\|WP_045450376.1\|515549_516179_+\|cysteine-hydrolase	gnl\|CDD\|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	1.33414e-54
NZ_AP014576.1\|WP_014190541.1\|495544_495868_+\|AzlD-domain-containing-protein	gnl\|CDD\|377512	pfam05437, AzlD, Branched-chain amino acid transport protein (AzlD). This family consists of a number of bacterial and archaeal branched-chain amino acid transport proteins. AzlD is known to be involved in conferring resistance to 4-azaleucine although its exact role is uncertain.	3.5555e-18
NZ_AP014576.1\|WP_045450373.1\|510918_512436_+\|DegQ-family-serine-endoprotease	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	3.38281e-178

>NZ_AP014576.1|WP_045450368.1|503304_504327_+|threonylcarbamoyl-AMP-synthase
MTIIYPGAAQIDEAAALLDAGELVAFPTETVYGLGGDAENPDAIARIYAAKGRPANHPVIVHLAPEADPGYWVREMPADAQKLIDAFWPGPLTLILKRAAHIPAAVSGGQDSVGVRCPSHPVAQQLLSAFHARRRGTGKQGGVAGPSANRFGHVSPTTAQHVRDEFGGAVHVLDGGAADVGIESTILDLSRGFPALLRPGHVSPQQIADVIGIAPRLPDGSDATAPRASGTLKAHYAPRTPLVLLPFSAMEPLLRRDGDRKIALVARASSAGEWARASHVHFVAAPEDPQSYARDLYGLLRALDRANVERILIEKLPETVEWIAVNDRLGRAAAAFEAEE
>NZ_AP014576.1|WP_045450367.1|502092_503280_+|5-(carboxyamino)imidazole-ribonucleotide-synthase
MNPQNSPISPILPGAWLGMVGGGQLGRMFCFAAQSMGYRVAVLDPDETSPAGAVADRHIRAAYDDRAALTELGRLCAAVSTEFENVPSASLEFLASCTFVSPAASCVAIAQDRVAEKRFIAESGVPVAPHVVIESADALGAIPDEKIAAVLPGILKTARMGYDGKGQVNVRNVDEVRHAHASLSGVPCVLEKRMPLKYEVSVLIARGGDGKSAVFPLAQNVHTSGILAKTVVPAPDASAALVAQAQDAALTIAAKLGYVGVLCVEFFVLEDGSLIANEMAPRPHNSGHYTVDACATSQFEQQVRAMTGMPLGDTRQHSPAAMLNLLGDIWFDGNKARAPAWAEVAAMPSARLHLYGKEEARRGRKMGHINFTAATLEEARTAARDCARMLHITID
>NZ_AP014576.1|WP_045450366.1|501509_502022_+|5-(carboxyamino)imidazole-ribonucleotide-mutase
MTNEVHTHNAPLVGVLMGSSSDWDVMKNAVAILQEFGVPYEAKVVSAHRMPDEMFAYAESARERGVRAIIAGAGGAAHLPGMLAAKTTLPVLGVPVASKYLKGVDSLHSIVQMPKGVPVATFAIGEAGAANAALFAVSILSATDSKYADALAAFRVKQNQAARDMALPPL
>NZ_AP014576.1|WP_014190545.1|500607_501498_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MSTLYESTIKSLPLLGRGKVRDNYAVGQDKLLIVTTDRLSAFDVVMGEPIPNKGRVLNTMADFWFEKLGHIVPNHNTGIDPATVVAPGEAEQVKGRAVVVKRLEPILVEAVVRGYLAGSGWKDYQATGSVCGVELPPGLQNAQKLPEPIFTPAAKAEMGHHDENITYDEMERRIGTELSATIKRISIQLYEEAAAYAATRGIIIADTKFEFGLDDKGELYLMDEVLTADSSRFWPADGYQVGTNPPSFDKQFVRDWLETQPWKKEPPAPKLPDDVIARTSEKYQEALQRLTGKTLD
>NZ_AP014576.1|WP_014190544.1|499386_500451_+|fructose-bisphosphate-aldolase-class-II
MPLVSMRQLLDHAAEHGYGLPAFNVNNLEQVQAIMSAANEVNAPVIMQASAGARKYAGEAFLRHLIEAAVESYPHIPVVMHQDHGQSPAVCMAAIRSGFTSVMMDGSLEADGKTVASYEYNVAVSKQVVEFSHSIGVTVEAELGVLGSLETMKGDKEDGHGAEGTMTREQLLTDVEQAADFVKQTQCDALAIAIGTSHGAYKFSKKPTGDILAIDRIREIHQRIPNTHLVMHGSSSVPQELLAEIREFGGDMKETYGVPVEEIQEGIKHGVRKVNIDTDLRLAITGAIRRYLFENPSKFDPRDYLKPAREAAKEICRQRYMQFGCEGMAGKIKPVSLDKIAEKYKSGALSQIVK
>NZ_AP014576.1|WP_014190543.1|497771_499208_+|pyruvate-kinase
MHRATKIVATIGPASTSPDILLQMLQAGLDVVRFNFSHGTADDHRQRAEIVREAARQVGREVAIMADLQGPKIRVGKFENNKTMLVAGNPFILDAGCELGNSERVGLDYKDLPRDLRAGDVLLLNDGLIVLDVTRVIGEEIHTTVKVGGELSNNKGINRQGGGLTAPALTEKDMEDIKTAMSLGADFVAVSFPKNATDMEMARQLANIAGAPYGIKPKMIAKIERAEAIPALQGILDASDGIMVARGDLAVEVGNAAVPALQKRMIRMARESNKLVITATQMMESMIHAPVPTRAEVSDVANAVLDGTDAVMLSAETAAGKYPVTTIETMAAVCIEAEKSEESQLDRDFLDRTFTRIDQSIAMGALFTAYHLGAKAVVALTESGSTALWMSRHWTHVPIFALTPRVASERTMSLYRNVTPLHVDTNMDRDAALNSALEVVVSKGYAARGDMVVLTVGEPMGQAGGTNTLKIVRVGDHF
>NZ_AP014576.1|WP_045450365.1|496228_497425_+|phosphoglycerate-kinase
MTKVLRFTDLIAEGKVSGKRVFIRADLNVPQDDDGNITEDTRVRASVPAIKAALDAGAAVMVTSHLGRPTEGQFKPEDSLAPVAKRLSELLGRDVPLVADWVDGVSVQPGNVVLLENCRVNKGEKKNDDGLAQKLAKLCDIYVNDAFGTAHRAEATTHGIAKYAPVACAGPLLAAELDALGKALGNPKRPLVAIVAGSKVSTKLTILKSLAEKVDQLIVGGGIANTFMLASGLKIGKSLAEADLLGEAKEIIEQARTRGASVPIPSDVVTAKEFAPTAKAQTKPVADVADDDMILDIGPDTAKALAAQLETAGTIVWNGPVGVFEFDQFGNGTKTLAAAIANSSAFSIAGGGDTLAAIAKYDIADKVSYISTGGGAFLEFLEGKTLPAVEVLESRAGA
>NZ_AP014576.1|WP_014190541.1|495544_495868_+|AzlD-domain-containing-protein
MSTLQVWLAIIGMGLVTAVTRALFLIGGERMVLPPRVQRVLRYAPAAALAGVVVPDLLATPSGISLGLGNHALWASVAGLAYYLKRRGMMGTIAVGMIVFTVLRLAA
>NZ_AP014576.1|WP_045450364.1|494801_495548_+|AzlC-family-ABC-transporter-permease
MPDRLSDTNRRAFFEGVRTFSPAVLATFSWGLVTGVAMTKSVLTVPQALGMSFLVYAGSSQLAVLPLFAAKLPLWTVLLTAAMVNLRFVIFSAGLAPHFAYLSLRRRLLLGYFNGDIIYLMFSKRNFPTGWQPGKEAFFWGLAVSSWLSWQISSVLGILLASLIPDNWGLELAGTLALIPLIVSAIATRSTLAAVAVASVVALLTFDLPYRFGLPLAVFAALLAGTLADVIAEKRDKRNKPAASGNTR
>NZ_AP014576.1|WP_075644198.1|493487_494408_-|branched-chain-amino-acid-transaminase
MSMADRDGKIWMDGKLIDWRDAKIHVLTHTLHYGMGVFEGVRAYKTAQGTAIFRLKEHTKRLLNSAKIFQMDVPFDAATLEAAQLEVVKANELESCYIRPIIWVGSEKLGVSAKGNTIHVAIAAWPWGAYLGEDGLAKGIRVKTSSFTRHHVNVSMVRAKASGWYVNSILANQEAVADGYDEALLLDVDGYVSEGSGENFFLVNNGKIYTPDLASCLDGITRDTVITLARDFGIPVIEKRITRDEVYTCDEAFFTGTAAEVTPIRELDNRTIGSGARGPITEKLQSAFFDVVGGKNEKYASWLAKV
>NZ_AP014576.1|WP_045450369.1|505415_506522_-|SGNH/GDSL-hydrolase-family-protein
MKKQRSMRAALTRFAQVATASAAFALIAACGGGGDDNNSTPPGGVKLQIVSFGDSLSDVGTYAPVAAANFGGGRFTTNPGQVWVQNVAQYYGDTLTPAMTGGFGVPPATQSGLGYAQGGALVTNPIGINHVSNDPANYQGALTVPVVQQVTNYLSAHGSFNSNQLVIVNGGGNDILYNFQLAQTGAITPAQASAAIGKAAIDLAGIIGKVLQSGATHVLVSNVPDIGTTPQGMMSSAANRALLTQASLGFNQALAGALTQAGLMSKVIYLDIVPVLAKVTANFGQFGFTVSNTGTACNLQAMAAAAQKFGEPNPAAFATSLFCSPETLTVAGADQTYMYADTVHPTTHLGALYAQAAEQVVAKSGLGK
>NZ_AP014576.1|WP_045450370.1|506754_508350_-|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase
MPLASRFASRRLSSFALAAVLACAALGPAPAAFARGGTKAESQAQSPERAAKGKRAAKNGKASRVAKASVPAGPLPASVMTALARAHVPLSSMSVVVQRIGAPTPLVSINANEPMLPASTMKLVTTYAGLSILGPDYRWKTTAYADGQIDTQGVLHGNLYIQGTGDPKLVPEELIDLVDQIRKNGITGIDGALVLDKRYFDASTRDLPAFDNDDSAPYNVGPDPLLYAFKSLSFTLTPNADGQVAIDVLPQLAQLQIDNELRVTRGACVGSLSAASPSVAQTQGGFVQASFIGDYPLRCGSRTVNVAALDHSTFFAGGFLALWKQAGGTFQGATREGPTPSGARLVGTHRSPVLSDVVRDINKFSNNVMARNLFLTIGAAQLKPPATTAKSAAAIQSFLKRSALPMNGLALDNGSGLSRDEHISAASLADLLQAANASPVAQVFVESLPIAGVDGTMRNRLTNAGAFGNAHIKTGTLRDVRAIAGYVGAANGESYVIVSFINDPRAEAARAAHDALLEWVYEGARKADLAE
>NZ_AP014576.1|WP_014190551.1|508609_509272_+|response-regulator
MRILLVEDDRMIAEGVRKALRADGFAVDWVQDGEAALTAVAGESYDLMLLDLGLPKRDGLDVLKTLRARANALPVLIVTARDAIADRVKGLDAGADDYLVKPFDLDELGARMRALIRRHAGRGESLVRHGELTLDPVGHQVTLAGNPVALSAREFALLEALMARPGAVLSKSQLEEKIYGWGEEIGSNTVEVYIHSLRKKLGADLIRNVRGLGYMVAKDA
>NZ_AP014576.1|WP_045450371.1|509271_510573_+|HAMP-domain-containing-protein
MRSIRRQLLIWLLALVIVGVGFAGWLIYRQALAEANELFDYQLQQIAAALPSEPFSSVLSSRSESDEGVVIQIWNRNGVLMYYSHPRVPLAPHAELGFSTEMTPRGEWRVYSAIVGDNVVQLAQPLSIRNRVAAGVAWRTLWPLVLLLPLLGVAIWVIVGRGLAPLQRVTRALDTRHPEALDPLSDQRLPQEVRPVVRALNALLSRLSAALDTQKAFVADAAHELRTPLAAVQIQAQLVGRAQDDDTRREALADLNEGIARATRLAEQLLALARSEPDGKAVETRVDLDELLEGCVRGYVLVAQERGVDLGIEASESASVKGDPDSLRVMFNNLIDNATKYTPRGGRVDVCVKLEGGNPLVEIADTGPGIPGEERERVFDRFYRVGEGVNRPRTDVAGSGLGLAIVRRIAVQHGATVSLGESEAGGLKVAVRF
>NZ_AP014576.1|WP_045450373.1|510918_512436_+|DegQ-family-serine-endoprotease
MKAKILTRSAVAAAVAVALSAGYVAGHNNVPAPQVIAPAQAAALMPAEAAAKTGIPDFSGLVETYGPAVVNISAKHVVKETSARSSRNQLPMDPDDPLYQFFKRFGGFPGFGGGQGGPGGPGADRPSEGLGSGFIVSSDGYILTNAHVVDNANVVTVKLTDKREYRAKVIGADKQSDVAVLKIEAKDLPTVKIGDPNGSKVGQWVVAIGSPYGFDNTVTSGIISAKSRALPNENYTPFIQTDVPVNPGNSGGPLFNLQGEVIGINSMIYSQTGGFQGLSFAIPINEAIKVKDALIKTGHVDRGRLGVTVQGMNQTLANSFGMKSPQGALVSSVEPGGPAAKAGLQPGDVITALNGVPVSDSTSLPSQVAGLSPGSSAKVTVWRDKSAKDLSVTIGALKDAKTASAKTGAGGDEASAQDARLGVAVRPLTPEEKQNDSLSRGLLVQQSGGAAASAGIQPGDVILAVNGQPVTSVQQLKSMVEHAGDSIALLIQRDDAQIFVPVDLG
>NZ_AP014576.1|WP_014190554.1|512576_513068_+|hypothetical-protein
MTNKTTGRLAAALVVAAMSAGMTGGAWAQASGTTGGTTADTSSAGNTNGGGLPQVQQQGDVSYTSGGVGLDESRALLREQAHWPLSLRFTGPTAEYLSGVTVRIAGGKGGDVLSTEAMGPYMLVKLPPGNYTVYAKYKDQEKKQSVNVSGPGKAKAAFHWNIQ
>NZ_AP014576.1|WP_045450374.1|513212_513590_+|DUF427-domain-containing-protein
MGTELKDGHEAAHGIEITLNGRRCRVIHQGVTYADTHASFTLIEAGAEKVHYFPRADVNMARLERSIHTTQCPMKGQATHYHLLTEDGPIENAAWSYEAPLDAAVKIKGYLAFYGSRVDRIDETS
>NZ_AP014576.1|WP_014190556.1|513664_514468_+|carbon-monoxide-dehydrogenase-subunit-G
MEVTDALRVPLDPAHVRDALGDLALLRASLDNCESFTRTPGGEYVLTLIVPLGALRARYEIRAHAAGRTRQAAHAEGEPAEPADAADTAYARTLSFKARGEGVGSLRGQIAVALNPDEDDSDSTWIEYTVWATVSGPLAGLPSRQIENALREGADDFFAEFCEVVRAKHGLPSMRAAGENAARRHVFLRPSSMSAAFSRRPGAMRAPSADAHASGVLRHRLHGHGFVHHDRDHSHDPHPLGLPAWAWAAMLVCIALFAYLAQHVGLG
>NZ_AP014576.1|WP_045450375.1|514464_515421_-|helix-turn-helix-domain-containing-protein
MSRHSIAVVAFDRISPFHLAVPCIVFGEERGGIGVPPFDFRVCAAEPRALATSAGFTIAARHSLDALDSADVVIVPSWRDPAETPPGALLDALRAAHARGARIVGLCLGSYVLAAAGLLDGRAATTHWAWADDFARRYPRVRLDPNVLYIDDENITTSAGTAAGLDCCLHVLRALAGSHAANQVARRLVVPPHRQGSQAQFIDEPLPGRANGEKLAGLLDWLRANLQTDHSLDALAARMAMSRRNFTRRFRQTTGTTVGAWLVGQRVALAQRLLEDTDLPVDRIAQTCGFGTGATLRQQFAQTLKTSPSAYRRAFRGV
>NZ_AP014576.1|WP_045450376.1|515549_516179_+|cysteine-hydrolase
MPRRALIVIDVQNEYVEGNLLIEYPDVNVSLANIGRAMDAAQEHGVSVVVVQNFAPESAPIFARGSAMAQLHETVASRPRAHYVEKSLPSAFAGTDLADWLTANDIDTIVIAGYMTHNCDDSTVKHAVHAGLSVEFLADATGAVPYENRAGKASAEEIHRVFTVVMQSRFAAVLSTDEWLAALESGEPPARDNIYASNQRARAGSAASR

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Crispr_ID: NZ_AP014576_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_AP014576_2

702606-703732

Orphan

Consensus_repeat	Method
GGTCTATCTCCGCGCACGCGGAGGAATC	CRISPRCasFinder
GGNCTATCTCCGCGCACGCGGAGGAA	CRT
GGCCTATCTCCGCGCACGCGGAGGAAAC	PILER-CR
GGTCTATCTCCGCGCACGCGGAGGAATC	PILER-CR

18 spacers

The CRISPR arrays of NZ_AP014576_2

>merge|NZ_AP014576|2|702606-703732|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
GGTCAATCTCCGCGCAGGTGGAGGAAACCAAGGAGTCAGCGAGACGACCCTTCGCCGCGAGGGCCTATCTCCGCGCACGCGGAGGAAACGCGCAGTCGCGCATCGTGGCGTTAAGTGCCGAGGGCCTATCTCCGCGCACGCGGAGGAAACTTCACGAATCTGCCGGCATCCCGCGACGATGGGGGCCTATCTCCGCGCACGCGGAGGAAACATCACTGGCTCTTGGGCGTGCTGACGATGCGCGGGCCTATCTCCGCGCACGCGGAGGAAACGGCGCGAGATTCAGCAATTCTTCATCGCTCGCGGGCCTATCTCCGCGCACCCGGAGGAAGCCGACAACCGAGAGGAACACGAAGTCGTGAACAAGGCCTATCTCCGCGCACGCGGAGGAATCTTTTTTATTTCGCGAACAAGTCTCCCTGTCCAGGGCCTATCTCCGCGCACGCGGAGGAATCGCGATCGCACCGGCGTCGATGAAGACCGTCAACGGCCTATCTCCGCGCACGCGGAGGAATCCAAGCGGCTAACTCACAATATTTCCGATAATCGGGTCTATCTCCGCGTACGCGGAGGAATCTCGCTCCACGATTGGCCGAGATTCCACACGCTGGGTCTATCTCCGCGCACGCGGAGGAATCTCAAGTGCTGCTTATTCATCGATCACTCCACGCGGTCTATCTCCGCGCACGCGGAGGAATCGAAATCGCCTTCCCGTCCGCGCAGGAAAAACGACGGTCTATCTCCGCGCACGCGGAGGAATCGGTCTGGTCCGCCTGAATGTCCCTCACTCTGCCGGTCTATCTCCGCGCACGCGGAGGAATCACGTCATCGGGGCTCTGCAAGCCATCGTACAAAGGTCTATCTCCGCGCACGCGGAGGAATCCGCCTCGCCCGCCCGCGTATCGAGCGCGACGCCGGTCTATCTCCGCGCACGCGGAGGAATCCTCTGGACGAGGTGGACAATGCGGTCATGGTGCGGTCTATCTCCGCGCACGCGGAGGAATCCGCGAAGATCGCGGTCCAGGCGGGCGTCAGATAGGTCTATCTCCGCGCACGCGGAGGAATCGCTTCCTTGCCGACGTGTCCCGTGAGCACCGCGGGTCTATCTCCGCGCACGCGGAGGAATC

>NZ_AP014576|2|2|702606-703732|CRISPRCasFinder
GGTCAATCTCCGCGCAGGTGGAGGAAAC	CAAGGAGTCAGCGAGACGACCCTTCGCCGCGAG
GGCCTATCTCCGCGCACGCGGAGGAAAC	GCGCAGTCGCGCATCGTGGCGTTAAGTGCCGAG
GGCCTATCTCCGCGCACGCGGAGGAAAC	TTCACGAATCTGCCGGCATCCCGCGACGATGGG
GGCCTATCTCCGCGCACGCGGAGGAAAC	ATCACTGGCTCTTGGGCGTGCTGACGATGCGCG
GGCCTATCTCCGCGCACGCGGAGGAAAC	GGCGCGAGATTCAGCAATTCTTCATCGCTCGCG
GGCCTATCTCCGCGCACCCGGAGGAAGC	CGACAACCGAGAGGAACACGAAGTCGTGAACAA
GGCCTATCTCCGCGCACGCGGAGGAATC	TTTTTTATTTCGCGAACAAGTCTCCCTGTCCAG
GGCCTATCTCCGCGCACGCGGAGGAATC	GCGATCGCACCGGCGTCGATGAAGACCGTCAAC
GGCCTATCTCCGCGCACGCGGAGGAATC	CAAGCGGCTAACTCACAATATTTCCGATAATCG
GGTCTATCTCCGCGTACGCGGAGGAATC	TCGCTCCACGATTGGCCGAGATTCCACACGCTG
GGTCTATCTCCGCGCACGCGGAGGAATC	TCAAGTGCTGCTTATTCATCGATCACTCCACGC
GGTCTATCTCCGCGCACGCGGAGGAATC	GAAATCGCCTTCCCGTCCGCGCAGGAAAAACGAC
GGTCTATCTCCGCGCACGCGGAGGAATC	GGTCTGGTCCGCCTGAATGTCCCTCACTCTGCC
GGTCTATCTCCGCGCACGCGGAGGAATC	ACGTCATCGGGGCTCTGCAAGCCATCGTACAAA
GGTCTATCTCCGCGCACGCGGAGGAATC	CGCCTCGCCCGCCCGCGTATCGAGCGCGACGCC
GGTCTATCTCCGCGCACGCGGAGGAATC	CTCTGGACGAGGTGGACAATGCGGTCATGGTGC
GGTCTATCTCCGCGCACGCGGAGGAATC	CGCGAAGATCGCGGTCCAGGCGGGCGTCAGATA
GGTCTATCTCCGCGCACGCGGAGGAATC	GCTTCCTTGCCGACGTGTCCCGTGAGCACCGCG
GGTCTATCTCCGCGCACGCGGAGGAATC

>NZ_AP014576|2|1|702606-703730|CRT
GGTCAATCTCCGCGCAGGTGGAGGAA	ACCAAGGAGTCAGCGAGACGACCCTTCGCCGCGAG
GGCCTATCTCCGCGCACGCGGAGGAA	ACGCGCAGTCGCGCATCGTGGCGTTAAGTGCCGAG
GGCCTATCTCCGCGCACGCGGAGGAA	ACTTCACGAATCTGCCGGCATCCCGCGACGATGGG
GGCCTATCTCCGCGCACGCGGAGGAA	ACATCACTGGCTCTTGGGCGTGCTGACGATGCGCG
GGCCTATCTCCGCGCACGCGGAGGAA	ACGGCGCGAGATTCAGCAATTCTTCATCGCTCGCG
GGCCTATCTCCGCGCACCCGGAGGAA	GCCGACAACCGAGAGGAACACGAAGTCGTGAACAA
GGCCTATCTCCGCGCACGCGGAGGAA	TCTTTTTTATTTCGCGAACAAGTCTCCCTGTCCAG
GGCCTATCTCCGCGCACGCGGAGGAA	TCGCGATCGCACCGGCGTCGATGAAGACCGTCAAC
GGCCTATCTCCGCGCACGCGGAGGAA	TCCAAGCGGCTAACTCACAATATTTCCGATAATCG
GGTCTATCTCCGCGTACGCGGAGGAA	TCTCGCTCCACGATTGGCCGAGATTCCACACGCTG
GGTCTATCTCCGCGCACGCGGAGGAA	TCTCAAGTGCTGCTTATTCATCGATCACTCCACGC
GGTCTATCTCCGCGCACGCGGAGGAA	TCGAAATCGCCTTCCCGTCCGCGCAGGAAAAACGAC
GGTCTATCTCCGCGCACGCGGAGGAA	TCGGTCTGGTCCGCCTGAATGTCCCTCACTCTGCC
GGTCTATCTCCGCGCACGCGGAGGAA	TCACGTCATCGGGGCTCTGCAAGCCATCGTACAAA
GGTCTATCTCCGCGCACGCGGAGGAA	TCCGCCTCGCCCGCCCGCGTATCGAGCGCGACGCC
GGTCTATCTCCGCGCACGCGGAGGAA	TCCTCTGGACGAGGTGGACAATGCGGTCATGGTGC
GGTCTATCTCCGCGCACGCGGAGGAA	TCCGCGAAGATCGCGGTCCAGGCGGGCGTCAGATA
GGTCTATCTCCGCGCACGCGGAGGAA	TCGCTTCCTTGCCGACGTGTCCCGTGAGCACCGCG
GGTCTATCTCCGCGCACGCGGAGGAA

>NZ_AP014576|2|1|702667-703121|PILER-CR
GGCCTATCTCCGCGCACGCGGAGGAAAC	GCGCAGTCGCGCATCGTGGCGTTAAGTGCCGAG
GGCCTATCTCCGCGCACGCGGAGGAAAC	TTCACGAATCTGCCGGCATCCCGCGACGATGGG
GGCCTATCTCCGCGCACGCGGAGGAAAC	ATCACTGGCTCTTGGGCGTGCTGACGATGCGCG
GGCCTATCTCCGCGCACGCGGAGGAAAC	GGCGCGAGATTCAGCAATTCTTCATCGCTCGCG
GGCCTATCTCCGCGCACCCGGAGGAAGC	CGACAACCGAGAGGAACACGAAGTCGTGAACAA
GGCCTATCTCCGCGCACGCGGAGGAATC	TTTTTTATTTCGCGAACAAGTCTCCCTGTCCAG
GGCCTATCTCCGCGCACGCGGAGGAATC	GCGATCGCACCGGCGTCGATGAAGACCGTCAAC
GGCCTATCTCCGCGCACGCGGAGGAATCCAAGCGGCTAACTCACAATATTTCCGATAATCGGGTCTATCTCCGCGTACGCGGAGGAATCTCGCTCCACGATTGGCCGAGATTCCACACGCTGGGTCTATCTCCGCGCACGCGGAGGAATC	TCAAGTGCTGCTTATTCATCGATCACTCCACGC
GGTCTATCTCCGCGCACGCGGAGGAATC	GAAATCGCCTTCCCGTCCGCGCAGGAAAAACGAC
GGTCTATCTCCGCGCACGCGGAGGAATC	GGTCTGGTCCGCCTGAATGTCCCTCACTCTGCC
GGTCTATCTCCGCGCACGCGGAGGAATC	ACGTCATCGGGGCTCTGCAAGCCATCGTACAAA
GGTCTATCTCCGCGCACGCGGAGGAATC	CGCCTCGCCCGCCCGCGTATCGAGCGCGACGCC
GGTCTATCTCCGCGCACGCGGAGGAATC	CTCTGGACGAGGTGGACAATGCGGTCATGGTGC
GGTCTATCTCCGCGCACGCGGAGGAATC	CGCGAAGATCGCGGTCCAGGCGGGCGTCAGATA
GGTCTATCTCCGCGCACGCGGAGGAATC	GCTTCCTTGCCGACGTGTCCCGTGAGCACCGCG


>NZ_AP014576|2|2|703216-703732|PILER-CR
	GCGCAGTCGCGCATCGTGGCGTTAAGTGCCGAG
GGCCTATCTCCGCGCACGCGGAGGAAAC	TTCACGAATCTGCCGGCATCCCGCGACGATGGG
GGCCTATCTCCGCGCACGCGGAGGAAAC	ATCACTGGCTCTTGGGCGTGCTGACGATGCGCG
GGCCTATCTCCGCGCACGCGGAGGAAAC	GGCGCGAGATTCAGCAATTCTTCATCGCTCGCG
GGCCTATCTCCGCGCACCCGGAGGAAGC	CGACAACCGAGAGGAACACGAAGTCGTGAACAA
GGCCTATCTCCGCGCACGCGGAGGAATC	TTTTTTATTTCGCGAACAAGTCTCCCTGTCCAG
GGCCTATCTCCGCGCACGCGGAGGAATC	GCGATCGCACCGGCGTCGATGAAGACCGTCAAC
GGCCTATCTCCGCGCACGCGGAGGAATCCAAGCGGCTAACTCACAATATTTCCGATAATCGGGTCTATCTCCGCGTACGCGGAGGAATCTCGCTCCACGATTGGCCGAGATTCCACACGCTGGGTCTATCTCCGCGCACGCGGAGGAATC	TCAAGTGCTGCTTATTCATCGATCACTCCACGC
GGTCTATCTCCGCGCACGCGGAGGAATC	GAAATCGCCTTCCCGTCCGCGCAGGAAAAACGAC
GGTCTATCTCCGCGCACGCGGAGGAATC	GGTCTGGTCCGCCTGAATGTCCCTCACTCTGCC
GGTCTATCTCCGCGCACGCGGAGGAATC	ACGTCATCGGGGCTCTGCAAGCCATCGTACAAA
GGTCTATCTCCGCGCACGCGGAGGAATC	CGCCTCGCCCGCCCGCGTATCGAGCGCGACGCC
GGTCTATCTCCGCGCACGCGGAGGAATC	CTCTGGACGAGGTGGACAATGCGGTCATGGTGC
GGTCTATCTCCGCGCACGCGGAGGAATC	CGCGAAGATCGCGGTCCAGGCGGGCGTCAGATA
GGTCTATCTCCGCGCACGCGGAGGAATC	GCTTCCTTGCCGACGTGTCCCGTGAGCACCGCG
GGTCTATCTCCGCGCACGCGGAGGAATC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_AP014576.1\|WP_085952626.1\|697046_697982_+\|agmatinase	unknown	unknown	gnl\|CDD\|212538
NZ_AP014576.1\|WP_041730955.1\|694565_695246_+\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|178807
NZ_AP014576.1\|WP_014190725.1\|708819_708999_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014576.1\|WP_041730191.1\|689834_690665_-\|Smr/MutS-family-protein	unknown	unknown	gnl\|CDD\|380164
NZ_AP014576.1\|WP_014190727.1\|710448_711753_-\|MHS-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NZ_AP014576.1\|WP_014190722.1\|706017_706785_+\|septum-site-determining-protein-MinC	unknown	unknown	gnl\|CDD\|234994
NZ_AP014576.1\|WP_014190724.1\|708263_708569_+\|YXWGXW-repeat-containing-protein	unknown	unknown	unknown
NZ_AP014576.1\|WP_014190723.1\|706874_707690_+\|septum-site-determining-protein-MinD	unknown	unknown	gnl\|CDD\|225447
NZ_AP014576.1\|WP_014190719.1\|703794_704145_-\|hypothetical-protein	unknown	unknown	unknown
NZ_AP014576.1\|WP_006999197.1\|707699_707954_+\|cell-division-topological-specificity-factor-MinE	unknown	unknown	gnl\|CDD\|184442
NZ_AP014576.1\|WP_014190720.1\|704381_705164_+\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NZ_AP014576.1\|WP_014190716.1\|697985_699305_-\|putative-hydroxymethylpyrimidine-transporter-CytX	unknown	unknown	gnl\|CDD\|274096
NZ_AP014576.1\|WP_014190726.1\|709248_710427_+\|OpgC-domain-containing-protein	unknown	unknown	gnl\|CDD\|378405
NZ_AP014576.1\|WP_014190714.1\|695930_696842_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NZ_AP014576.1\|WP_014190710.1\|690839_691835_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NZ_AP014576.1\|WP_041730193.1\|699531_700848_+\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NZ_AP014576.1\|WP_014190721.1\|705338_705863_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NZ_AP014576.1\|WP_045450402.1\|700989_702288_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NZ_AP014576.1\|WP_014190711.1\|692199_694515_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
NZ_AP014576.1\|WP_144403928.1\|695283_695691_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_AP014576.1\|WP_085952626.1\|697046_697982_+\|agmatinase	gnl\|CDD\|212538	cd11592, Agmatinase_PAH, Agmatinase-like family includes proclavaminic acid amidinohydrolase. This agmatinase subfamily contains bacterial and fungal/metazoan enzymes, including proclavaminic acid amidinohydrolase (PAH, EC 3.5.3.22) and Pseudomonas aeruginosa guanidinobutyrase (GbuA) and guanidinopropionase (GpuA). PAH hydrolyzes amidinoproclavaminate to yield proclavaminate and urea in clavulanic acid biosynthesis. Clavulanic acid is an effective inhibitor of beta-lactamases and is used in combination with amoxicillin to prevent the beta-lactam rings of the antibiotic from hydrolysis and, thus keeping the antibiotic biologically active. GbuA hydrolyzes 4-guanidinobutyrate (4-GB) into 4-aminobutyrate and urea while GpuA hydrolyzes 3-guanidinopropionate (3-GP) into beta-alanine and urea. Mutation studies show that significant variations in two active site loops in these two enzymes may be important for substrate specificity. This subfamily belongs to the ureohydrolase superfamily, which includes arginase, agmatinase, proclavaminate amidinohydrolase, and formiminoglutamase.	3.9809e-180
NZ_AP014576.1\|WP_041730955.1\|694565_695246_+\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|178807	PRK00031, lolA, outer membrane lipoprotein chaperone LolA.	1.66574e-78
NZ_AP014576.1\|WP_041730191.1\|689834_690665_-\|Smr/MutS-family-protein	gnl\|CDD\|380164	NF033154, endonuc_SmrA, DNA endonuclease SmrA. YdaL is a small endonuclease with homology to the C-terminal domain found in the endonuclease MutS2, but not found in the related mismatch repair protein MutS. The biological role of this endonuclease is not yet known. As one of two Small MutS2-Related proteins in E. coli, This protein was designated SmrA by Gui, et al. (PMID:21276852). The term SMR is much better known for describing a large family of Small Multidrug Resistance (SMR) efflux transporters, but in that context is used with three capital letters.	4.17736e-46
NZ_AP014576.1\|WP_014190727.1\|710448_711753_-\|MHS-family-MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.27371e-167
NZ_AP014576.1\|WP_014190722.1\|706017_706785_+\|septum-site-determining-protein-MinC	gnl\|CDD\|234994	PRK01973, PRK01973, septum site-determining protein MinC.	1.78756e-148
NZ_AP014576.1\|WP_014190723.1\|706874_707690_+\|septum-site-determining-protein-MinD	gnl\|CDD\|225447	COG2894, MinD, Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning].	4.73691e-162
NZ_AP014576.1\|WP_006999197.1\|707699_707954_+\|cell-division-topological-specificity-factor-MinE	gnl\|CDD\|184442	PRK13989, PRK13989, cell division topological specificity factor MinE; Provisional.	6.35631e-48
NZ_AP014576.1\|WP_014190720.1\|704381_705164_+\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	9.20375e-153
NZ_AP014576.1\|WP_014190716.1\|697985_699305_-\|putative-hydroxymethylpyrimidine-transporter-CytX	gnl\|CDD\|274096	TIGR02358, purine-cytosine_transport_protein, putative hydroxymethylpyrimidine transporter CytX. On the basis of a phylogenomic study of thiamine biosythetic, salvage, and transporter genes and a highly conserved RNA element THI, this protein family has been identified as a probable transporter of hydroxymethylpyrimidine (HMP), the phosphorylated (by ThiD) form of which gets joined (by ThiE) to hydroxyethylthiazole phosphate to make thiamine phosphate. [Transport and binding proteins, Nucleosides, purines and pyrimidines, Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	1.39977e-99
NZ_AP014576.1\|WP_014190726.1\|709248_710427_+\|OpgC-domain-containing-protein	gnl\|CDD\|378405	pfam10129, OpgC_C, OpgC protein. This domain, found in various hypothetical and OpgC prokaryotic proteins. It is likely to act as an acyltransferase enzyme.	6.08124e-87
NZ_AP014576.1\|WP_014190714.1\|695930_696842_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.43995e-31
NZ_AP014576.1\|WP_014190710.1\|690839_691835_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	1.44704e-154
NZ_AP014576.1\|WP_041730193.1\|699531_700848_+\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NZ_AP014576.1\|WP_014190721.1\|705338_705863_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.17529e-12
NZ_AP014576.1\|WP_014190711.1\|692199_694515_+\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
NZ_AP014576.1\|WP_045450402.1\|700989_702288_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0

>NZ_AP014576.1|WP_045450402.1|700989_702288_+|serine--tRNA-ligase
MLDIQHLRKDLDGVAKRLADRGYTLDVAAFAALEAERREIQTRTEELQARRNSLSKQIGAMKGRGEDTSAVMAEVSGIGDTMKESAAKLDDVQKRLSDLMLTVPNLPHESVPVGNDETQNVEVRRWGTPRAFDFEVRDHVDVGAPLGLDFETGAKLSGARFTLLRGQIARLHRALAQFMIDTHTEQHGYTEAYTPYIVNPEILYGTGQLPKFADDMFRVEKGGDENTVTQYLISTSEISLTNTVRDSILEADALPVKLTAHSPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQVTSPEHSYAALDEMVGQAETILQKLELPYRVITLCTGDMGFSAAKTFDLEVWLPAQNTYREISSCSNTEAFQARRMQARFRNAQGKPEFVHTLNGSGLAVGRTLVAVLENFQNADGSVTIPAALRPYMRGAERIEVAASV
>NZ_AP014576.1|WP_041730193.1|699531_700848_+|replication-associated-recombination-protein-A
MFEENRGTVPLAERLRPRTIDDVIGQKHLLGPSKPLRVAFESGEAHSMILWGPPGVGKTTLARLMADAFHAQFISLSAVLSGVKDIREAVETAQIHRANGHQTLVFVDEVHRFNKSQQDAFLPHVESGLFVFVGATTENPSFEVNSALLSRAAVYVLRSLDADELKELLERATKELGGLTFTDEARDALIGSADGDGRKLLNNLEIVARAAAQQKQTDVDGALLGSALAENLRRFDKGGDAFYDQISALHKSVRGSNPDAALYWFCRMLDGGADPRYMARRIVRMAWEDIGLADPRAARITLDAAETYERLGSPEGELALAQALVYLAVAPKSNAGYNAYNEARRFVSKDQSRGVPVHLRNAPTKLMKELGYGHEYRYAHDEPDAYAAGETYLPDGMRDPHWYRPTPRGLEGKIGEKLDRLAELDEAWRREHREEKKR
>NZ_AP014576.1|WP_014190716.1|697985_699305_-|putative-hydroxymethylpyrimidine-transporter-CytX
MQQETIGQHDDSATYAPLTPVPPERRAFGTSDAFALWFSLGIGLLVAQAGALLVPGLSLPHALVAIAIGTSIGVVLLALAGVVGTDTGLAAMSSLRPTLGVRGASVPAVLNAIQLVGWGSFEIIVMRDSADALAKQSFHFSMPLVWTLIFGALATLLAVSGPLSFVRRFLRSWGIWLLLGGAGWLTWNLLAKHDISALMSRPGTGEMAFGAGIDLVVAMPLSWLPLIADYTRFGKSAGGTFRGTLLGYGIANLWFYALGAIYGLAAGGGDALLTTAFAQAGGGLALFLILIDETDNAFADIHSAAVSTGTFWARASVPMLSCAFGALCTLVALVVEMGKYQNFLLLIGSVFAPLFGVVLADHFIVRKRRIDAAVLADVHGRYGYSGGWHVSAFIAWGIGIAAYHAINQWLPNLGATLPALALGAVCYLLLVSGKRRAYA
>NZ_AP014576.1|WP_085952626.1|697046_697982_+|agmatinase
MSGNQMPRCGGITTMMRLPHVPSAEGLDACFVGVPFDLGTSNRTGARFGPRQVRSESVLLRPYNMATRAAPFDSLRVADLGDVAINPYNLLDSIDRIERAYREILKHGCKPLTLGGDHTIALPILRAIHAKHGKVGLIHIDAHADVNDTMFGEKIAHGTPFRRAVEEGLLDCSRVVQIGLRGTGYEAGDFDWCREQGFRVVQTEECWNKSLAPLMEEVRAQMGDGPVYITFDIDGIDPAFAPGTGTPEIAGLTVPQALEIVRGARGLNIVGADLVEVAPPYDPFGTTALLGANLAFELLCVLPGVEYRTAK
>NZ_AP014576.1|WP_014190714.1|695930_696842_-|LysR-family-transcriptional-regulator
MFTHLSDLDLRLIRVFLAIVDAGGVSSAQATLNVGQSTISTQLATLETRLGYRLCERGRGGFALTSRGEQFVDACRTLLAAVDTFDSTARNVGRKLVGTLTLGMIGNTPVSANARVSEAIARFRQRDESVRIAVLVRSPGELEEMLLSERIQMAIGYFWHRVPSLEYTEIFAEDQLAYCGREHPLFARAGRVSAAQAFEHDWAWRSYPLPEAGELVPRHIGAVADNMEAVAMLVLSGRHLGYLPEHFAAPYVKEGLLAPLNPKTMRYRVAFQMVTRATRASGVRGAKREIVEAFIEDMQAAHS
>NZ_AP014576.1|WP_144403928.1|695283_695691_-|hypothetical-protein
MTGASTTRVPGGVITFRGALVAPPFDVSIGTTPTLGISTAEQTRSGESSGNTLYVTYGADPRNPPNADVSLSVAGPATSGGQALAASFRDGKGRKMTPGIGGEYHLGALGGTLAIRTKDDASSSATRVTIVTNYR
>NZ_AP014576.1|WP_041730955.1|694565_695246_+|outer-membrane-lipoprotein-chaperone-LolA
MKQFTGNPFTKALGAAIFSASMLFASHAFASGTEQLKAFVSQVRAARGDFTQQEIKAPGKTNNGATSNAVPTKGATSSGTFMFARPGKFIWSYQKPYSQVLQADGDKLYVYDKDLNQVTVRTLGGALGASPAAILFGSNDLDKNFNLRDAGEKGGIDWLELTPKSKDTQFETVGIGFKDGNLQAMELHDVFGNVTLLTFSNIQKNPPIKSDTFKFTVPKGADVING
>NZ_AP014576.1|WP_014190711.1|692199_694515_+|DNA-translocase-FtsK
MAKATYSASPQALPHRMSRLFTEIRWILQVALGLFLVMALLSYSRKDPSWTHAVSVDHIANWAGRVGAYTSDILLLVFGLSSYWLIVLLARRIVANYRKITLPPAVDEDAPKDRTWLAEAFAFVLVLLASDGIEALRMWSLKVQLPRAPGGVVGDVVARHVSHALGFTGATLFLLIALAIGLSLYFRFSWLSVCEKVGDGILNAITGAQLRREAGRDRKLGEEAASKREGKVVRSREKSEDHEPVMIVPAAPAPARSERAEKEKQVPLFKDLPGDSTLPPLALLDPPPKTQETIAADTLEYTSRLIEKKLKDFGVDVSVVAAYPGPVVTRYEIEPATGVKGSQIVGLAKDLARSLSLVSIRVVETIPGKNFMALELPNQRRQTVKLSEILGSEVYANGASPLTMGLGKDIGGNPVCADLAKMPHLLVAGTTGSGKSVGINAMILSLLYKASADQVRLILIDPKMLEMSVYEGIPHLLCPVVTDMRQAGHALNWAVAEMERRYKLMSKMGVRNLASFNTKIDEAKKRDEKIPNPFSLTPDEPEPLTRLPNIVVVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITGLIKANVPTRMAFQVSSKIDSRTILDQQGAESLLGMGDMLYLPPGSGLPVRVHGAFVSDEEVHRVVEKLREHGEPNYIEGILEGGLAGDGDEGSAGAGGTGGADGESDPLYDQAVEVVIKNKRASISLVQRHLRIGYNRAARLLEQMENSGLVSAMSSNGNREILSPARDAE
>NZ_AP014576.1|WP_014190710.1|690839_691835_-|thioredoxin-disulfide-reductase
MSSPKHAKVLILGSGPAGYSAAVYAARANLSPLLITGLAQGGQLMTTTDVENWPGDPSGVQGPELMQRLEEHARAFNTDIVFDHIHTAKLNERPMRLIGDSGEYTCDSLIIATGASAQYLGMPSEEAFMGKGVSACATCDGFFYRNGEVAVIGGGNTAVEEAIYLAGIAKKVTVVHRRDKFRAEPILIDRLLAKEKEGVVDIKWNHVLDEVLGDDSGVTGLRIKDTQSGQTTDLALQGVFVAIGHKPNTDLFAGQLEMKGGYIITKGGTSGDATATSLAGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRYLETINETPTPHSMSHEADR
>NZ_AP014576.1|WP_041730191.1|689834_690665_-|Smr/MutS-family-protein
MPKNLPHPNEPKARQKPAPRPVEPAPSKPADVAAAVRREGLAGLSSLKRALKDNAEKREVQRVAAVRAEREAVADADEFRRAIGEVERLKTPPRTTITRVPPPPEPLQSRRDEEAVLQEALSDEYDPESLLDIDETLSYYRPGISQEVVKKLRRGAWIVQAQLDLHGMRREEAREALAEFIREAVKRGLRCLRVIHGKGLGSIGKAPVLKGKVRAWLVQKSEVIAFCQARPHDGGAGAVLVLLQPGGAPRHHNHPQDKTHAQRLGKNPHPGPDSAS
>NZ_AP014576.1|WP_014190719.1|703794_704145_-|hypothetical-protein
MTLHRFAFFCAALSGAAALAACSSTSEPELRASKPVIHVSSARAASDISSCLQRMIPSAQARRDQGSTELMVGSNAWLVTLTPSVYGSVVKVQQSSSDDGGVPEPELRFDIARCTT
>NZ_AP014576.1|WP_014190720.1|704381_705164_+|type-I-methionyl-aminopeptidase
MAITLKTPADIEKLRISGRMAAEVLAMIAEHVRPGVTTDELDAICNRFIVDELKAIPANVGYMGFPKTVCTSVNHVVCHGIPGPKELKDGDIINIDVAIIKDGYYGDTSRMYYAGTPSEQARRLAETTYEAMVAGIREVRPGATLGDVGAAIQSVAHREGFSVVREYCGHGIGRVYHEDPQVLHYGQRGAGLRLKPGLVFTIEPMINAGRAATQQSRDGWTVTTKDRSLSAQWEHMVAVTEEGFELLTPWPDGTGPYEAP
>NZ_AP014576.1|WP_014190721.1|705338_705863_+|GNAT-family-N-acetyltransferase
MSPSLTVSRIAAQQGSVLRELRTASLREAPYAFGETLEDALLVDPSSFEETAALHANSPRLATFLLYTEGHPCGLVHAYIEETPGARAFVSALWVAPAVRHLRGGELLMNVATRWLAAQGAAEVHAWISEENRTAMRFYERLGFGPTGERRAMPSHEEEAESLFVRHMQAEDDL
>NZ_AP014576.1|WP_014190722.1|706017_706785_+|septum-site-determining-protein-MinC
MSLNKTPFFELRSGSVDTLLFVVKTPDLNALRTELTRRFEATPEFFAGDVVAIDVRRLAEQERVSLVDLEALLKSVRMRPIGIVALPAQTWAIQWANEGGLPILEARDRRGAPKPSADEAKPNTEAAAVIEAAVAKEPPPASLPQPATIIDRPLRSGQQVYAKGDLIVLGLVSYGAEVIAEGNIHIYAPLRGRALAGVHGNLDARIFCTCLEPELISIAGIYRTTENPLPADVASKPVQIWLQEEKLMIEPLRLT
>NZ_AP014576.1|WP_014190723.1|706874_707690_+|septum-site-determining-protein-MinD
MAKIIVVTSGKGGVGKTTTSASFASALALRGHKTAVIDFDVGLRNLDLIMGCERRVVYDLINVIQGEANLHQALIKDKKSENLYILPASQTRDKDALTLEGVEKVIEELIKMDFEYIVCDSPAGIESGALMAMHFADEALIVTNPEVSSVRDSDRILGILSSKTKRAIEGKEPVKEHLLITRYNPKRVSEGEMLSLSDIQEILRIDLIGVIPESEAVLHASNQGLPAVHLDGTDVAESYKDVVSRFLGEEKTLRFTDYQKPGLLQRIFGTK
>NZ_AP014576.1|WP_006999197.1|707699_707954_+|cell-division-topological-specificity-factor-MinE
MSILSFLLGEKRKSASVAKERLQLIIAHERAGGKAAADYLPALQRELVAVISKYVKISDDDIRVSLERQDDLEVLEVKIEIPQA
>NZ_AP014576.1|WP_014190724.1|708263_708569_+|YXWGXW-repeat-containing-protein
MKLSCRHLLARAALLAAGVVSMSGAFADVVIVAPSAPPAPRFEPVPAARAGFVWDAGHWNWEGRYVWVPGHWIAVRPGARWAPGVWAPFRGRYRYIPGHWI
>NZ_AP014576.1|WP_014190725.1|708819_708999_-|hypothetical-protein
MNIHLQSAHLVAIVTIALVTALLLAVKFRPATWRGVVLEAVVANVGAILAVLAFEVLTA
>NZ_AP014576.1|WP_014190726.1|709248_710427_+|OpgC-domain-containing-protein
MTSPTRSLEVDFFRGIVLLIIAVDHITGSVLSRFTLHQYAFCDSAEVFVFLGGYASAAAYTALATRRSDSAARRRFFKRSWEIYRAYLFTAFLMLIGGGLLMALKIDTPMVQYTEWPAFLARPAGLLVDIALLRQQPYLSAVLPMYSVFALAVPVIVPLAQKRPVVAVFGSLLVWLAAMPLLRFLPGTYGEAWSFNPFAWQLMFMTGVLARIQPVSGTFHAGKIARWLTAGAIALALTFAFFKLFLETQALPGYMKQNLATLRIVSFAAIAWIVARAVYAGWVARLARRLPGIVTIGQQGLVCFIAGACVSLVLDSALRAMGVLGLGRYPSHWILGLIADGIAIASLLWLARFWADRKAAKAARAKVAERQASRIPVMKGPLPAHISNRRDR
>NZ_AP014576.1|WP_014190727.1|710448_711753_-|MHS-family-MFS-transporter
MAAPSLSAAQPGDGSQSASRVIFASFIGTAIEFYDFYVYATAAALVIGPVFFPHDSPAAQALSAFVTFGIAFFARPIGSFLFGHFGDRIGRKSTLVASLLVMGVSTTLIGFVPGYDSIGSAAPVLLCILRFGQGIGLGGEWGGAALLATEYAPQGKRGLFGMFPQLGPSIGFLASNGLFFGLALSLSDEQFRSWGWRVPFIVSAVLVALGLYVRLKIAETPAFRAAVERRERVKVPVATLLSSHLAPTLLGAFAMVVCYTLFYISTVFSLSFGVAKLHFARETFLGLLCFAVLFMAIATPISAIASDRFGRKPVLVVGCVAAILSGFAMAPLLGSGDTIQVALFLTIELFLMGVTFAPMGALLPELFPTNVRYTGAGVAYNLGGILGASVAPYIAQLLANRGGLSWVGGYVSAAAAVSLIAVLCMRETRHIKLN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_AP014576_2	2.17\|703611\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703611-703643	33	NZ_AP014576.1	1172396-1172428	0	1.0
NZ_AP014576_2	2.18\|703672\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703672-703704	33	NZ_AP014576.1	2279617-2279649	0	1.0

1. spacer 2.17|703611|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to position: 1172396-1172428, mismatch: 0, identity: 1.0

cgcgaagatcgcggtccaggcgggcgtcagata	CRISPR spacer
cgcgaagatcgcggtccaggcgggcgtcagata	Protospacer
*********************************

2. spacer 2.18|703672|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to position: 2279617-2279649, mismatch: 0, identity: 1.0

gcttccttgccgacgtgtcccgtgagcaccgcg	CRISPR spacer
gcttccttgccgacgtgtcccgtgagcaccgcg	Protospacer
*********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP024308	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3a, complete sequence	332767-332799	7	0.788
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1176286-1176318	7	0.788
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	2001932-2001964	7	0.788
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	182625-182657	7	0.788
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP017244	Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence	2236261-2236293	7	0.788
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	334016-334048	7	0.788
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP016463	Bosea sp. RAC05 plasmid pBSY19_1, complete sequence	161565-161597	8	0.758
NZ_AP014576_2	2.18\|703672\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703672-703704	33	NC_012521	Rhodococcus opacus B4 plasmid pROB02, complete sequence	126189-126221	8	0.758
NZ_AP014576_2	2.26\|703059\|35\|NZ_AP014576\|CRT	703059-703093	35	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	334016-334050	8	0.771
NZ_AP014576_2	2.26\|703059\|35\|NZ_AP014576\|CRT	703059-703093	35	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	326884-326918	8	0.771
NZ_AP014576_2	2.3\|702756\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	702756-702788	33	NZ_CP013589	Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence	924531-924563	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000032	Agrobacterium fabrum strain CFBP2788 plasmid pTi_CFBP2788, complete sequence	51083-51115	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	KY000034	Agrobacterium sp. strain C58PMP90 plasmid pTi_C58PMP90, complete sequence	4103-4135	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	KY000036	Agrobacterium sp. strain GV3101 plasmid pTi_GV3101, complete sequence	5369-5401	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP032929	Agrobacterium tumefaciens strain 1D1460 plasmid pTi1D1460, complete sequence	198610-198642	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NC_002147	Agrobacterium tumefaciens MAFF301001 plasmid pTi-SAKURA, complete sequence	2709-2741	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NC_011990	Agrobacterium radiobacter K84 plasmid pAtK84b, complete sequence	114730-114762	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP030831	Neorhizobium sp. NCHU2750 plasmid pTiNCHU2750, complete sequence	40632-40664	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NC_003065	Agrobacterium fabrum str. C58 plasmid Ti, complete sequence	36969-37001	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_MK439382	Agrobacterium tumefaciens strain CFBP2178 plasmid pTiCFBP2178, complete sequence	36581-36613	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_MK439383	Agrobacterium tumefaciens strain CFBP1935 plasmid pTiCFBP1935, complete sequence	36581-36613	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_MK439386	Agrobacterium tumefaciens strain T37 plasmid pTiT37, complete sequence	35554-35586	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_MK318986	Agrobacterium rhizogenes strain C6.5 plasmid pTiC6.5, complete sequence	203291-203323	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_MK439385	Agrobacterium tumefaciens strain Kerr27 plasmid pTiKerr27, complete sequence	36970-37002	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_MK439384	Agrobacterium tumefaciens strain Kerr108 plasmid pTiKerr108, complete sequence	36581-36613	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_MK439381	Agrobacterium tumefaciens strain Sule1 plasmid pTiSule1, complete sequence	36581-36613	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_MF511177	Agrobacterium rhizogenes strain C5.7 plasmid pTiC5.7, complete sequence	203291-203323	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000041	Agrobacterium tumefaciens strain CFBP296 plasmid pTi_CFBP296, complete sequence	57339-57371	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000044	Agrobacterium fabrum strain CFBP1933 plasmid pTi_CFBP1933, complete sequence	195304-195336	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000073	Agrobacterium tumefaciens strain Tun188 plasmid pTi_Tun188, complete sequence	185868-185900	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000057	Agrobacterium fabrum strain CFBP5505 plasmid pTi_CFBP5505, complete sequence	35279-35311	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000071	Agrobacterium tumefaciens strain Tun183 plasmid pTi_Tun183, complete sequence	206502-206534	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000047	Agrobacterium genomosp. 1 strain CFBP2516 plasmid pTi_CFBP2516, complete sequence	123698-123730	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000046	Agrobacterium genomosp. 1 strain CFBP2177 plasmid pTi_CFBP2177, complete sequence	46418-46450	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000051	Agrobacterium genomosp. 1 strain CFBP5503 plasmid pTi_CFBP5503, complete sequence	55333-55365	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000056	Agrobacterium vitis strain Tun201 plasmid pTi_Tun201, complete sequence	51436-51468	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP021816	Sinorhizobium meliloti strain M270 plasmid accessoryB, complete sequence	94553-94585	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000052	Agrobacterium tumefaciens strain CFBP7000 plasmid pTi_CFBP7000, complete sequence	159933-159965	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000049	Agrobacterium rhizogenes strain CFBP4423 plasmid pTi_CFBP4423, complete sequence	107919-107951	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000055	Agrobacterium rubi strain Tun159 plasmid pTi_Tun159, complete sequence	188626-188658	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000043	Agrobacterium rhizogenes strain CFBP1905 plasmid pTi_CFBP1905, complete sequence	115898-115930	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000048	Agrobacterium rhizogenes strain CFBP2746 plasmid pTi_CFBP2746, complete sequence	27435-27467	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000053	Agrobacterium genomosp. 1 strain DC12-001 plasmid pTi_DC12-001, complete sequence	107783-107815	9	0.727
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_KY000054	Agrobacterium tumefaciens strain Tun154 plasmid pTi_Tun154, complete sequence	124684-124716	9	0.727
NZ_AP014576_2	2.26\|703059\|35\|NZ_AP014576\|CRT	703059-703093	35	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	182625-182659	9	0.743
NZ_AP014576_2	2.26\|703059\|35\|NZ_AP014576\|CRT	703059-703093	35	NZ_CP024308	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3a, complete sequence	332765-332799	9	0.743
NZ_AP014576_2	2.26\|703059\|35\|NZ_AP014576\|CRT	703059-703093	35	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1176284-1176318	9	0.743
NZ_AP014576_2	2.26\|703059\|35\|NZ_AP014576\|CRT	703059-703093	35	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	2001930-2001964	9	0.743
NZ_AP014576_2	2.26\|703059\|35\|NZ_AP014576\|CRT	703059-703093	35	NZ_CP017244	Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence	2236261-2236295	9	0.743
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP020539	Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence	473071-473103	10	0.697
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_CP035000	Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence	68005-68037	10	0.697
NZ_AP014576_2	2.8\|703061\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703061-703093	33	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	1182316-1182348	10	0.697
NZ_AP014576_2	2.13\|703367\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	703367-703399	33	MK967384	Gordonia phage Sidious, complete genome	9690-9722	10	0.697
NZ_AP014576_2	2.3\|702756\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	702756-702788	33	NZ_CP013562	Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence	1069851-1069883	11	0.667
NZ_AP014576_2	2.3\|702756\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	702756-702788	33	NZ_CP013579	Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence	1055940-1055972	11	0.667
NZ_AP014576_2	2.3\|702756\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	702756-702788	33	NZ_CP013579	Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence	1057050-1057082	11	0.667
NZ_AP014576_2	2.3\|702756\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	702756-702788	33	NZ_CP013531	Rhizobium phaseoli strain R723 plasmid pRphaR723d, complete sequence	944883-944915	11	0.667
NZ_AP014576_2	2.3\|702756\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	702756-702788	33	NZ_CP013546	Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence	950320-950352	11	0.667
NZ_AP014576_2	2.3\|702756\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	702756-702788	33	NZ_CP013584	Rhizobium phaseoli strain N261 plasmid pRphaN261d, complete sequence	944882-944914	11	0.667
NZ_AP014576_2	2.3\|702756\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	702756-702788	33	NZ_CP013573	Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence	1055940-1055972	11	0.667
NZ_AP014576_2	2.3\|702756\|33\|NZ_AP014576\|CRISPRCasFinder,PILER-CR	702756-702788	33	NZ_CP013573	Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence	1057050-1057082	11	0.667

1. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP024308 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3a, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaagacctcgaag	Protospacer
  ************* *********** . **

2. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaagacctcgaag	Protospacer
  ************* *********** . **

3. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaagacctcaaag	Protospacer
  ************* *********** . **

4. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaagacctcaaag	Protospacer
  ************* *********** . **

5. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP017244 (Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatcgcaccggcgtcgatgaagaccgtcaac-	CRISPR spacer
tagatggcaccggcgacgatgaagacc-tcgatg	Protospacer
  *** ********* *********** **.*.

6. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.788

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
gcgatcgcgccggcgtcgatgcagccggccgat	Protospacer
********.************ ** * *.*.*.

7. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP016463 (Bosea sp. RAC05 plasmid pBSY19_1, complete sequence) position: , mismatch: 8, identity: 0.758

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
ggaaccgcaccgtcgtcgatgcagaccgttgag	Protospacer
* .*.******* ******** *******..*

8. spacer 2.18|703672|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NC_012521 (Rhodococcus opacus B4 plasmid pROB02, complete sequence) position: , mismatch: 8, identity: 0.758

gcttccttgccgacgtgtcccgtgagcaccgcg	CRISPR spacer
accgacttgccgacgcgttccgtgagcacggtg	Protospacer
.*.  **********.**.********** *.*

9. spacer 2.26|703059|35|NZ_AP014576|CRT matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.771

tcgcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
gcgcgatcgcgccggcgtcgatgcagccggccgat	Protospacer
 *********.************ ** * *.*.*.

10. spacer 2.26|703059|35|NZ_AP014576|CRT matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 8, identity: 0.771

tcgcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tcgcgatcggcccggcgtcgatgaaatccaccccc	Protospacer
*********  **************. **..*  *

11. spacer 2.3|702756|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP013589 (Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence) position: , mismatch: 9, identity: 0.727

ttcacgaatctgccggcatcccgcgacgatggg	CRISPR spacer
tgctgaaatctgccggcatcacgggacgatcaa	Protospacer
* *  .************** ** ****** ..

12. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000032 (Agrobacterium fabrum strain CFBP2788 plasmid pTi_CFBP2788, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

13. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to KY000034 (Agrobacterium sp. strain C58PMP90 plasmid pTi_C58PMP90, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

14. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to KY000036 (Agrobacterium sp. strain GV3101 plasmid pTi_GV3101, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

15. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP032929 (Agrobacterium tumefaciens strain 1D1460 plasmid pTi1D1460, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

16. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NC_002147 (Agrobacterium tumefaciens MAFF301001 plasmid pTi-SAKURA, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

17. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NC_011990 (Agrobacterium radiobacter K84 plasmid pAtK84b, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

18. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP030831 (Neorhizobium sp. NCHU2750 plasmid pTiNCHU2750, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

19. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NC_003065 (Agrobacterium fabrum str. C58 plasmid Ti, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

20. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_MK439382 (Agrobacterium tumefaciens strain CFBP2178 plasmid pTiCFBP2178, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

21. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_MK439383 (Agrobacterium tumefaciens strain CFBP1935 plasmid pTiCFBP1935, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

22. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_MK439386 (Agrobacterium tumefaciens strain T37 plasmid pTiT37, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

23. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_MK318986 (Agrobacterium rhizogenes strain C6.5 plasmid pTiC6.5, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

24. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_MK439385 (Agrobacterium tumefaciens strain Kerr27 plasmid pTiKerr27, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

25. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_MK439384 (Agrobacterium tumefaciens strain Kerr108 plasmid pTiKerr108, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

26. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_MK439381 (Agrobacterium tumefaciens strain Sule1 plasmid pTiSule1, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

27. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_MF511177 (Agrobacterium rhizogenes strain C5.7 plasmid pTiC5.7, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

28. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000041 (Agrobacterium tumefaciens strain CFBP296 plasmid pTi_CFBP296, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

29. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000044 (Agrobacterium fabrum strain CFBP1933 plasmid pTi_CFBP1933, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

30. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000073 (Agrobacterium tumefaciens strain Tun188 plasmid pTi_Tun188, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

31. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000057 (Agrobacterium fabrum strain CFBP5505 plasmid pTi_CFBP5505, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

32. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000071 (Agrobacterium tumefaciens strain Tun183 plasmid pTi_Tun183, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

33. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000047 (Agrobacterium genomosp. 1 strain CFBP2516 plasmid pTi_CFBP2516, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

34. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000046 (Agrobacterium genomosp. 1 strain CFBP2177 plasmid pTi_CFBP2177, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

35. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000051 (Agrobacterium genomosp. 1 strain CFBP5503 plasmid pTi_CFBP5503, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

36. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000056 (Agrobacterium vitis strain Tun201 plasmid pTi_Tun201, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

37. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP021816 (Sinorhizobium meliloti strain M270 plasmid accessoryB, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaatacttcgacc	Protospacer
  ************* ******* **. . * *

38. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000052 (Agrobacterium tumefaciens strain CFBP7000 plasmid pTi_CFBP7000, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

39. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000049 (Agrobacterium rhizogenes strain CFBP4423 plasmid pTi_CFBP4423, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

40. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000055 (Agrobacterium rubi strain Tun159 plasmid pTi_Tun159, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

41. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000043 (Agrobacterium rhizogenes strain CFBP1905 plasmid pTi_CFBP1905, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

42. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000048 (Agrobacterium rhizogenes strain CFBP2746 plasmid pTi_CFBP2746, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

43. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000053 (Agrobacterium genomosp. 1 strain DC12-001 plasmid pTi_DC12-001, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

44. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_KY000054 (Agrobacterium tumefaciens strain Tun154 plasmid pTi_Tun154, complete sequence) position: , mismatch: 9, identity: 0.727

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
tagatcgcaccggcgacgatgaacacttcgacc	Protospacer
  ************* ******* **. . * *

45. spacer 2.26|703059|35|NZ_AP014576|CRT matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 9, identity: 0.743

tcgcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
gatagatcgcaccggcgacgatgaagacctcaaag	Protospacer
    ************* *********** . **

46. spacer 2.26|703059|35|NZ_AP014576|CRT matches to NZ_CP024308 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3a, complete sequence) position: , mismatch: 9, identity: 0.743

tcgcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
gatagatcgcaccggcgacgatgaagacctcgaag	Protospacer
    ************* *********** . **

47. spacer 2.26|703059|35|NZ_AP014576|CRT matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 9, identity: 0.743

tcgcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
gatagatcgcaccggcgacgatgaagacctcgaag	Protospacer
    ************* *********** . **

48. spacer 2.26|703059|35|NZ_AP014576|CRT matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.743

tcgcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
gatagatcgcaccggcgacgatgaagacctcaaag	Protospacer
    ************* *********** . **

49. spacer 2.26|703059|35|NZ_AP014576|CRT matches to NZ_CP017244 (Rhizobium etli 8C-3 plasmid pRsp8C3c, complete sequence) position: , mismatch: 9, identity: 0.743

tcgcgatcgcaccggcgtcgatgaagaccgtcaac-	CRISPR spacer
gatagatggcaccggcgacgatgaagacc-tcgatg	Protospacer
    *** ********* *********** **.*.

50. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP020539 (Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence) position: , mismatch: 10, identity: 0.697

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
ggcgcggcaccggcgtcgatgaagccggtctgg	Protospacer
*  .. ****************** * *** .

51. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP035000 (Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence) position: , mismatch: 10, identity: 0.697

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
atcatcggaccggcgtcgatgatgacctcgctc	Protospacer
.. **** ************** **** .   *

52. spacer 2.8|703061|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 10, identity: 0.697

gcgatcgcaccggcgtcgatgaagaccgtcaac	CRISPR spacer
acgatcgcaccggcatccatgaagatgatgcga	Protospacer
.*************.** *******. .*  .

53. spacer 2.13|703367|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to MK967384 (Gordonia phage Sidious, complete genome) position: , mismatch: 10, identity: 0.697

ggtctggtccgcctgaatgtccctcactctgcc	CRISPR spacer
gtaaccaatcgcctgaatgaccctgactctgcc	Protospacer
*   . . .********** **** ********

54. spacer 2.3|702756|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP013562 (Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence) position: , mismatch: 11, identity: 0.667

ttcacgaatctgccggcatcccgcgacgatggg	CRISPR spacer
gcttaaaatctgccggcatcacgggacgatcaa	Protospacer
 ..  .************** ** ****** ..

55. spacer 2.3|702756|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP013579 (Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence) position: , mismatch: 11, identity: 0.667

ttcacgaatctgccggcatcccgcgacgatggg	CRISPR spacer
gcttaaaatctgccggcatcacgggacgatcaa	Protospacer
 ..  .************** ** ****** ..

56. spacer 2.3|702756|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP013579 (Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence) position: , mismatch: 11, identity: 0.667

ttcacgaatctgccggcatcccgcgacgatggg	CRISPR spacer
gcttaaaatctgccggcatcacgggacgatcaa	Protospacer
 ..  .************** ** ****** ..

57. spacer 2.3|702756|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP013531 (Rhizobium phaseoli strain R723 plasmid pRphaR723d, complete sequence) position: , mismatch: 11, identity: 0.667

ttcacgaatctgccggcatcccgcgacgatggg	CRISPR spacer
gcttaaaatctgccggcatcacgggacgatcaa	Protospacer
 ..  .************** ** ****** ..

58. spacer 2.3|702756|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP013546 (Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence) position: , mismatch: 11, identity: 0.667

ttcacgaatctgccggcatcccgcgacgatggg	CRISPR spacer
gcttaaaatctgccggcatcacgggacgatcaa	Protospacer
 ..  .************** ** ****** ..

59. spacer 2.3|702756|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP013584 (Rhizobium phaseoli strain N261 plasmid pRphaN261d, complete sequence) position: , mismatch: 11, identity: 0.667

ttcacgaatctgccggcatcccgcgacgatggg	CRISPR spacer
gcttaaaatctgccggcatcacgggacgatcaa	Protospacer
 ..  .************** ** ****** ..

60. spacer 2.3|702756|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP013573 (Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence) position: , mismatch: 11, identity: 0.667

ttcacgaatctgccggcatcccgcgacgatggg	CRISPR spacer
gcttaaaatctgccggcatcacgggacgatcaa	Protospacer
 ..  .************** ** ****** ..

61. spacer 2.3|702756|33|NZ_AP014576|CRISPRCasFinder,PILER-CR matches to NZ_CP013573 (Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence) position: , mismatch: 11, identity: 0.667

ttcacgaatctgccggcatcccgcgacgatggg	CRISPR spacer
gcttaaaatctgccggcatcacgggacgatcaa	Protospacer
 ..  .************** ** ****** ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1035587 : 1058347

Pseudomonas_phage(20.0%)

transposase,head,integrase,protease,tail

attL 1034911:1034926|attR 1062193:1062208

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1034911:1034926	attL	NA	NA	NA	NA
WP_045450419.1\|1035587_1036781_-\|integrase	site-specific integrase	A0A1W6JTA0	Pseudomonas_phage	2.7e-119	58.5
WP_144403877.1\|1036940_1037618_-	hypothetical protein	NA	NA	NA	NA
WP_144403878.1\|1037968_1038445_-	hypothetical protein	NA	NA	NA	NA
WP_045450423.1\|1039022_1039451_-	hypothetical protein	NA	NA	NA	NA
WP_045450426.1\|1039832_1040603_-	ATP-binding protein	D2XQ17	Bacillus_virus	6.2e-08	26.5
WP_045450427.1\|1040599_1042246_-\|transposase	IS21 family transposase	U5N3F9	Enterobacteria_phage	2.7e-16	27.7
WP_175585589.1\|1042384_1042561_-	hypothetical protein	NA	NA	NA	NA
WP_045450428.1\|1042620_1042911_-	hypothetical protein	NA	NA	NA	NA
WP_175585590.1\|1042924_1043080_-	hypothetical protein	NA	NA	NA	NA
WP_045450429.1\|1043076_1043511_-	hypothetical protein	NA	NA	NA	NA
WP_083972793.1\|1043555_1044989_-\|head,protease	HK97 family phage prohead protease	A0A0R6PHN0	Moraxella_phage	1.1e-29	44.4
WP_045450430.1\|1045079_1045400_-	hypothetical protein	NA	NA	NA	NA
WP_045450431.1\|1045400_1045715_-	hypothetical protein	NA	NA	NA	NA
WP_083972795.1\|1045711_1048489_-\|tail	phage tail length tape measure family protein	C4ML16	Xanthomonas_virus	2.1e-13	21.7
WP_045450432.1\|1048478_1048658_-	hypothetical protein	NA	NA	NA	NA
WP_045450433.1\|1048843_1049071_-	hypothetical protein	NA	NA	NA	NA
WP_045450434.1\|1049109_1049307_-	hypothetical protein	NA	NA	NA	NA
WP_144403880.1\|1049487_1050045_+	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_041730274.1\|1050726_1050987_-	hypothetical protein	NA	NA	NA	NA
WP_041730275.1\|1051395_1051605_-	hypothetical protein	NA	NA	NA	NA
WP_041730996.1\|1051724_1052678_-	CHAD domain-containing protein	NA	NA	NA	NA
WP_014191008.1\|1052955_1054542_+	inorganic phosphate transporter	NA	NA	NA	NA
WP_045450436.1\|1054553_1055057_-	hypothetical protein	NA	NA	NA	NA
WP_144403881.1\|1055287_1055890_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_045450144.1\|1057051_1058347_-\|transposase	IS701 family transposase	NA	NA	NA	NA
1062193:1062208	attR	NA	NA	NA	NA

DBSCAN-SWA_2

2197153 : 2205495

Eptesipox_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_045450906.1\|2197153_2198038_+	alpha/beta hydrolase	A0A220T682	Eptesipox_virus	5.4e-24	30.4
WP_014192029.1\|2198060_2198984_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	7.1e-43	36.5
WP_041730565.1\|2199292_2200456_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_014192031.1\|2200524_2201427_-	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	2.2e-52	39.5
WP_014192032.1\|2201692_2202079_-	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_014192033.1\|2202154_2203147_-	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	8.8e-31	32.8
WP_014192034.1\|2203154_2204129_-	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.2e-11	25.0
WP_014192035.1\|2204094_2205495_-	UDP-glucose/GDP-mannose dehydrogenase family protein	M4QRY4	Micromonas_pusilla_virus	3.0e-16	28.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage