CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP006872	Paenibacillus polymyxa SQR-21 chromosome, complete genome	2 crisprs	csa3,WYL,DEDDh,cas3,cas5,cas8c,cas7,cas4,cas1,cas2,DinG,RT	0	6	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP006872_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006872_1

2309202-2310838

TypeI

I-C:NA

Consensus_repeat	Method
GTCGCACTCTATAT-GAGTGCGTGGATTGAAAT	PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CRT

24 spacers

cas3,cas5,cas8c,cas7,cas4,cas1,cas2

The CRISPR arrays of NZ_CP006872_1

>merge|NZ_CP006872|1|2309202-2310838|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAATGATTTCCCATAAAACCTTTTGTTTAAGGTTAATGCCGTCGCACTCTATATGAGTGCGTGGATTGAAATTATTAAAAGAAACGGCCCTCTGATCGTGGGGATCGTCGCACTCTATATGAGTGCGTGGATTGAAATACGTCCAACAGGACGATTATCAAAGCGTTTTGGAACGGTCGCACTCTATATGAGTGCGTGGATTGAAATTAGGCCTTGGTTTCTGTATTTTCAACGAACCGGAACAGTCGCACTCTATATGAGTGCGTGGATTGAAATTACCTAACTGGGAGAAGCATCAAAATGTAGATGGTCGCACTCTATATGAGTGCGTGGATTGAAATTTAATGAGTATCAGCATTTACTGTTTGATGCGACGTCGCACTCTATATGAGTGCGTGGATTGAAATATAACACAAACAACAAAAGACTGGTCTTTAATAGACGTCGCACTCTATATGAGTGCGTGGATTGAAATTACAGAATAAAGCGCAGGCAGGCGTTCAACTAAAGTCGCACTCTATATGAGTGCGTGGATTGAAATCAGTTTTCGATGGCTATTAGATCGCCCTCAAAAGTCGCACTCTATATGAGTGCGTGGATTGAAATATAACACAAACAACAAAAGACTGGTCTTTAATAGACGTCGCACTCTATATGAGTGCGTGGATTGAAATTACAGAATAAAGCGCAGGCAGGCGTTCAACTAAAGTCGCACTCTATATGAGTGCGTGGATTGAAATCAGTTTTCGATGGCTATTAGATCGCCCTCAAAAGTCGCACTCTATATGAGTGCGTGGATTGAAATGTAATGTCCGTAGAAATGCCTGACGCGCGCGCAGTCGCACTCTATATGAGTGCGTGGATTGAAATAATTTATCTCCCTTGATTACAGGAAAAAAAATCCAAGTCGCACTCTATATGAGTGCGTGGATTGAAATCGTTTACGAGTCTCGTGGAGTCAGAACATTATAACGTCGCACTCTATATGAGTGCGTGGATTGAAATATGAGCGTATCCGTGGCCTTAATTGACTCGTTGAGTCGCACTCTATATGAGTGCGTGGATTGAAATTGCTGTACTTGTAGCAACTTGAGATTGTCTAATAATCGTCGCACTCTATATGAGTGCGTGGATTGGAATCCGAAACAAAGGAAAAATACTCAAAATTCATTGAGTCGCACTCTATATGAGTGCGTGGATTGAAATTTTTACCAACTGACAAGGGTATCTCTCCTTTATAAGTCGCACTCTATATGAGTGCGTGGATTGAAATTCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGGGTCGCACTCTATATGAGTGCGTGGATTGAAATTCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGGGTCGCACTCTATATGAGTGCGTGGATTGAAATTCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGGGTCGCACTCTATATGAGTGCATGGATTGAAATAACTAAATAAACAACAAAGGACTCCATACTGGTTGTCGCACTCTATATGAGTGCGTGGATTGAAATTAAAATTTTTGGAAAAGGGTAGGGGGCTCAAATTGTCGCACTCTATATGAGTGCGTGAATTAAAAT

>NZ_CP006872|1|1|2309202-2310838|PILER-CR
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GATTTCCCATAAAACCTTTTGTTTAAGGTTAATGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TATTAAAAGAAACGGCCCTCTGATCGTGGGGATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACGTCCAACAGGACGATTATCAAAGCGTTTTGGAACG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TAGGCCTTGGTTTCTGTATTTTCAACGAACCGGAACA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACCTAACTGGGAGAAGCATCAAAATGTAGATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTAATGAGTATCAGCATTTACTGTTTGATGCGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATAACACAAACAACAAAAGACTGGTCTTTAATAGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACAGAATAAAGCGCAGGCAGGCGTTCAACTAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAGTTTTCGATGGCTATTAGATCGCCCTCAAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATAACACAAACAACAAAAGACTGGTCTTTAATAGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACAGAATAAAGCGCAGGCAGGCGTTCAACTAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAGTTTTCGATGGCTATTAGATCGCCCTCAAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GTAATGTCCGTAGAAATGCCTGACGCGCGCGCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AATTTATCTCCCTTGATTACAGGAAAAAAAATCCAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CGTTTACGAGTCTCGTGGAGTCAGAACATTATAAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATGAGCGTATCCGTGGCCTTAATTGACTCGTTGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGCTGTACTTGTAGCAACTTGAGATTGTCTAATAATC
GTCGCACTCTATATGAGTGCGTGGATTGGAAT	CCGAAACAAAGGAAAAATACTCAAAATTCATTGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTTACCAACTGACAAGGGTATCTCTCCTTTATAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGG
GTCGCACTCTATATGAGTGCATGGATTGAAAT	AACTAAATAAACAACAAAGGACTCCATACTGGTT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TAAAATTTTTGGAAAAGGGTAGGGGGCTCAAATT
GTCGCACTCTATATGAGTGCGTGAATTAAAAT

>NZ_CP006872|1|1|2309202-2310838|CRISPRCasFinder
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GATTTCCCATAAAACCTTTTGTTTAAGGTTAATGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TATTAAAAGAAACGGCCCTCTGATCGTGGGGATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACGTCCAACAGGACGATTATCAAAGCGTTTTGGAACG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TAGGCCTTGGTTTCTGTATTTTCAACGAACCGGAACA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACCTAACTGGGAGAAGCATCAAAATGTAGATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTAATGAGTATCAGCATTTACTGTTTGATGCGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATAACACAAACAACAAAAGACTGGTCTTTAATAGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACAGAATAAAGCGCAGGCAGGCGTTCAACTAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAGTTTTCGATGGCTATTAGATCGCCCTCAAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATAACACAAACAACAAAAGACTGGTCTTTAATAGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACAGAATAAAGCGCAGGCAGGCGTTCAACTAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAGTTTTCGATGGCTATTAGATCGCCCTCAAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GTAATGTCCGTAGAAATGCCTGACGCGCGCGCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AATTTATCTCCCTTGATTACAGGAAAAAAAATCCAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CGTTTACGAGTCTCGTGGAGTCAGAACATTATAAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATGAGCGTATCCGTGGCCTTAATTGACTCGTTGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGCTGTACTTGTAGCAACTTGAGATTGTCTAATAATC
GTCGCACTCTATATGAGTGCGTGGATTGGAAT	CCGAAACAAAGGAAAAATACTCAAAATTCATTGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTTACCAACTGACAAGGGTATCTCTCCTTTATAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGG
GTCGCACTCTATATGAGTGCATGGATTGAAAT	AACTAAATAAACAACAAAGGACTCCATACTGGTT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TAAAATTTTTGGAAAAGGGTAGGGGGCTCAAATT
GTCGCACTCTATATGAGTGCGTGAATTAAAAT

>NZ_CP006872|1|1|2309202-2310838|CRT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GATTTCCCATAAAACCTTTTGTTTAAGGTTAATGCC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TATTAAAAGAAACGGCCCTCTGATCGTGGGGATC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ACGTCCAACAGGACGATTATCAAAGCGTTTTGGAACG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TAGGCCTTGGTTTCTGTATTTTCAACGAACCGGAACA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACCTAACTGGGAGAAGCATCAAAATGTAGATG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTAATGAGTATCAGCATTTACTGTTTGATGCGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATAACACAAACAACAAAAGACTGGTCTTTAATAGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACAGAATAAAGCGCAGGCAGGCGTTCAACTAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAGTTTTCGATGGCTATTAGATCGCCCTCAAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATAACACAAACAACAAAAGACTGGTCTTTAATAGAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TACAGAATAAAGCGCAGGCAGGCGTTCAACTAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CAGTTTTCGATGGCTATTAGATCGCCCTCAAAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	GTAATGTCCGTAGAAATGCCTGACGCGCGCGCA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	AATTTATCTCCCTTGATTACAGGAAAAAAAATCCAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	CGTTTACGAGTCTCGTGGAGTCAGAACATTATAAC
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	ATGAGCGTATCCGTGGCCTTAATTGACTCGTTGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TGCTGTACTTGTAGCAACTTGAGATTGTCTAATAATC
GTCGCACTCTATATGAGTGCGTGGATTGGAAT	CCGAAACAAAGGAAAAATACTCAAAATTCATTGA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TTTTACCAACTGACAAGGGTATCTCTCCTTTATAA
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGG
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TCTCTTGTTGTTTGGTTTATTGCCAGGTGTACCAGG
GTCGCACTCTATATGAGTGCATGGATTGAAAT	AACTAAATAAACAACAAAGGACTCCATACTGGTT
GTCGCACTCTATATGAGTGCGTGGATTGAAAT	TAAAATTTTTGGAAAAGGGTAGGGGGCTCAAATT
GTCGCACTCTATATGAGTGCGTGAATTAAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006872.1\|WP_017427972.1\|2314928_2316836_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP006872.1\|WP_025364683.1\|2311294_2311609_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006872.1\|WP_013370782.1\|2297002_2297242_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006872.1\|WP_017427968.1\|2308148_2308958_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NZ_CP006872.1\|WP_025364682.1\|2307046_2307883_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238083
NZ_CP006872.1\|WP_013370786.1\|2302879_2303416_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP006872.1\|WP_016821030.1\|2302031_2302874_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006872.1\|WP_017427973.1\|2316918_2317794_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_CP006872.1\|WP_013370788.1\|2306281_2307034_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NZ_CP006872.1\|WP_025364687.1\|2322409_2323807_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP006872.1\|WP_017427975.1\|2318436_2319468_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP006872.1\|WP_019687040.1\|2324164_2324332_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	unknown	unknown	gnl\|CDD\|378175
NZ_CP006872.1\|WP_017427974.1\|2317780_2318440_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP006872.1\|WP_025364685.1\|2314211_2314928_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP006872.1\|WP_025364681.1\|2304150_2306196_+\|membrane-protein	unknown	unknown	gnl\|CDD\|236545
NZ_CP006872.1\|WP_025364686.1\|2319478_2319769_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP006872.1\|WP_025364684.1\|2311614_2314098_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP006872.1\|WP_025364680.1\|2298019_2302015_+\|type-VII-secretion-protein-EssC	unknown	unknown	gnl\|CDD\|274860
NZ_CP006872.1\|WP_007430133.1\|2303672_2303948_+\|WXG100-family-type-VII-secretion-target	unknown	unknown	gnl\|CDD\|274862
NZ_CP006872.1\|WP_013370783.1\|2297631_2297952_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP006872.1\|WP_017427972.1\|2314928_2316836_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	1.75598e-168
NZ_CP006872.1\|WP_017427975.1\|2318436_2319468_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP006872.1\|WP_025364684.1\|2311614_2314098_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.39476e-71
NZ_CP006872.1\|WP_025364682.1\|2307046_2307883_+\|hypothetical-protein	gnl\|CDD\|238083	cd00143, PP2Cc, Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.	0.0025833
NZ_CP006872.1\|WP_013370786.1\|2302879_2303416_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	2.35911e-07
NZ_CP006872.1\|WP_025364681.1\|2304150_2306196_+\|membrane-protein	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	3.86365e-12
NZ_CP006872.1\|WP_017427973.1\|2316918_2317794_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	4.97551e-130
NZ_CP006872.1\|WP_013370788.1\|2306281_2307034_+\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	3.92385e-08
NZ_CP006872.1\|WP_025364686.1\|2319478_2319769_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.26636e-30
NZ_CP006872.1\|WP_019687040.1\|2324164_2324332_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	5.35762e-08
NZ_CP006872.1\|WP_017427974.1\|2317780_2318440_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	3.21027e-27
NZ_CP006872.1\|WP_025364685.1\|2314211_2314928_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	9.0233e-94
NZ_CP006872.1\|WP_025364687.1\|2322409_2323807_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	0.00935747
NZ_CP006872.1\|WP_017427968.1\|2308148_2308958_+\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	6.24113e-90
NZ_CP006872.1\|WP_025364680.1\|2298019_2302015_+\|type-VII-secretion-protein-EssC	gnl\|CDD\|274860	TIGR03928, T7_EssCb_Firm, type VII secretion protein EssC, C-terminal domain. This model describes the C-terminal domain, or longer subunit, of the Firmicutes type VII secretion protein EssC. This protein (homologous to EccC in Actinobacteria) and the WXG100 target proteins are the only homologous parts of type VII secretion between Firmicutes and Actinobacteria. [Protein fate, Protein and peptide secretion and trafficking].	0
NZ_CP006872.1\|WP_007430133.1\|2303672_2303948_+\|WXG100-family-type-VII-secretion-target	gnl\|CDD\|274862	TIGR03930, WXG100_ESAT6, WXG100 family type VII secretion target. Members of this protein family include secretion targets for the two main variants of type VII secretion systems (T7SS), one found in the Actinobacteria, one found in the Firmicutes. This model was derived through iteration from pfam06013. The best characterized member of this family is ESAT-6 from Mycobacterium tuberculosis. Members of this family usually are ~100 amino acids in length but occasionally have a long C-terminal extension.	5.92216e-14

>NZ_CP006872.1|WP_017427968.1|2308148_2308958_+|SDR-family-oxidoreductase
MSYTYAGGARFEGKTALITGAGSGIGKATAIQMAREGANVALFDVSNDRILETEREINAIREGSARAFDVDIADPVRVEKAVLEAVELFGGLHIIFANAGINGVVGPIEELSIEDWRQTLSTNLDGTFLTVKYTIPHLKKNGGGSIIITSSINGNQRFTSFGMSAYSTSKAGQTGFAKMAALELAKFRIRVNVIYPGAISTNIDETTEKSEGLKQITIPVQFPEGDQPLADGPGQPEQVADLVTFLASDHSRHITGAQIVIDGAESLLF
>NZ_CP006872.1|WP_025364682.1|2307046_2307883_+|hypothetical-protein
MNPLLSLLPTSKKKGLNARLTQQFAYISSQTGDQPLSSHHSRFMCRYGYGRSAESASMGESGQDFAAVRIHKSVCCFVLCDGVGLSYRGDFAARYLGSSLLDWMEQRQDLSANQLREYLERLAGAATEELDRQPLDHESGLMRSVLEDKRRQGSQSMYICGKIELPKRGTRGRLRLAWQGDSRLRLWNGTEEISELFNHTFSTAERWSTSRGPIGGKPHWYERSIPADMPMRLQVYTDGLSDLDPIREPVPDEQIQVLLDASHTGGLDDDAAFIELQW
>NZ_CP006872.1|WP_013370788.1|2306281_2307034_+|VWA-domain-containing-protein
MNYTIQASQRTPALIIYLIDISASMNMLMEGRRRIDVVYEAISLAIRQMVFRSTKGNRLTARYRIAILAYSDDVYDLLNGVKGIDEIAAIGSLPDLTPKRFSDSAKAFLQAERILQAELPGMQDCPAPLVCHMTDGVSTGDDPEPIAKRIMNMSVPDGNVLVENIFLSDRLLETPIQDPRRWKGLTHNTPLQDEHAVKLRNMSSVLPESYREMLFEADYQLGEGAIMMLPGTCAELVSIGFQMSAATPVR
>NZ_CP006872.1|WP_025364681.1|2304150_2306196_+|membrane-protein
MSFQPNPGDELIINGTAYVVGRHPAAPGLAYAQAGRQGIVYQLIAKNGAPHEAKALKVFFPKFRIPAMVYQSEHMETYGDIPGLQVCKRDVLTPERNGSLIAEQPDLLYAVLMPWVHGMTWFDCLTDQRQLEASDSLALARALAGIGSAMEQKGLAHCDLSAPNVMLPFFSEVELPEGTSAVELVDVEQMYSTKMDRPDALLAGSPGYAAHRTVHSGLWSAYADRFAGAIIIGEMLGWSDRVVVDKAWGESYFDQHEMQTPCERYFILRKSLEARWGSKVVELFSRAWDSQDLSSCPTFGEWLVVLNAVTEQEILVEDTETEPAATDTVGVAAVSGASSEAVSSLATPAPLKAEQAEMLNQAALEQGERGVTDKLFRQARELEQQNKPAAALEVYRSLYHFVEDGSPLHVEVSAAITGLEEQLNPKMPEQPEKSKAWYRSKMFIVTASAAVVLLAAGIPTVSILADQSNQRQIEAAKQEEAVKAAKAAEEKLVAEQEAAQKSLTEKQRQEAEQQAKQQALAAQKQQEEQKKQQALIAQQVKYEAYLAQKEQNKQAAAKLAKQKAYDQQEKYEKYLALKKEQEARAAKEEAARKAAAEAEQKRKDAVQARNKENVLQLISLYNKAYASQEGGSTAKAKSFAKRFRALYDSNPSYYRSVGEVGYRASSIYNFLGDTNFRLPKI
>NZ_CP006872.1|WP_007430133.1|2303672_2303948_+|WXG100-family-type-VII-secretion-target
MAGRILITPEQVDQVANQFKQSGEQSQQIVSSLTQSISGMEGQWEGMTKQRFFQEFQEASKQMQAFVTTLNSISQELTAIANKFRTVDQAK
>NZ_CP006872.1|WP_013370786.1|2302879_2303416_+|WXG100-family-type-VII-secretion-target
MRIRVEPDVLRGLSGQLQHAAEQIQQLTAGLEQALQSLDWDVSAREAILNQWMQAKRMSEQIHAYLHTSGTQLNRKAEQFQSVDHNYQTILPFASQPLGRPVTMLDWSNQQSPSILPGQASEGSSLISNPQSVVHAIAGVQPSDVGTLHQDILKQASSSSPQDWYFTDPSIARDQPVA
>NZ_CP006872.1|WP_016821030.1|2302031_2302874_+|hypothetical-protein
MLTFQASKQKLITLKAKELFFLAGVLGSDRLLGVEDPFKGYLAEELAEEWEQVKAALLEKGYLKQADKGKELAMPPTVFSRVAIAGLSNRACRIRYVRGGKQFEGYLHCTNERVVELVKSVDEPDEYRLYDLGNVEKACETLIDKMGWVDRLVPESPALMFSKQAFNKIYEQSAGESLSQISSKLTEASGDEEGAMRLAQSLSSRVAEGELQLLVWNGREWESQRAAFVLCPAMNWIFRMSSAGNGDWLIAAMASRDQFVDLLLNWLKQSAVTEEVTEEG
>NZ_CP006872.1|WP_025364680.1|2298019_2302015_+|type-VII-secretion-protein-EssC
MNVLYQRSPRLRPALREEKLEILRPPAEPSKPSFSIISILIPLMMTLVTIGFYVYMSRTGKMGNSNYLMFQMVTVVMMLTSYTIPFFVYLNNKKEYKRKLEERDRMYREQLQKHREELKMKREEQVRTLYEIHGDPQICTQIVKNRNSSLWERSPEDEDFLQVRIGTGQVPFHIKLQIPRPDGYDRDPLLGAADELEEEFRLVDAASITLPLFQSKVIGLVGEREHTLAALRVILAQVTVRHSPDEVKIASFYDEREESEWTWMRWLPHVWDDDRIQRMMSDRSSSAHQLADFLFARLNRRKNNRNERQGKGMEAPCYVIVLSDTQLIEEEPLLPLLLEDGRAIDACTIVLASRKEALPMQCQLIVEASKEQGVYALKSESAEVEQQSFKPDRLSKEEADALARYMAPIRLKRSSASDIPAVLPLFDMMSVASVEELDVADRWRRNRHPDTLPVPMGVRAGGKKIMINLHDKIERQGHGPHGLIAGTTGSGKSEVIQSIVASLAAEFHPHDLAFMLIDYKGGGMSNTFVNLPHVVGTITNLDNNLIERAKISLKAELVRRQKILNDAGNLQHIDEYYRLLRQRQEQPLPHLVIIIDEFAQLKRDQPEFMDELISIAAIGRTLGVHLILATQKPAGVVDDKIWSNSRFRICLRVQSEGDSRDMLKIPNAAWITKPGRGYFQVGSDEVFEEMQFAWSGAPYIGNRDISSALPVHEVRLNGKREALLTGGERASSGLKGEEAPKQLQVFIDYIAKEAAKAGIERLQGPWLPPLPEMLDLTNLPQCTEIDSTSSSLELKSLIGLVDDLPNQRQEPMYASLDHGHWAVYGMPGMGKTTFLHTLLMSTAQRYAVNHWNGYIIDMGRTMRDFGELPQIGAVMMAEEDDRIKRLFRYLFKMVALRKEMLSEAGVKTISSFRRSAVEDVPQIVVVIDGYLNFRNAYPDENELLESLLREGGSLGITFIITANRITDVFEKFRSNIPNAVSFELADPSDYYYAVGRPAKTPGPLIPGRALVKGHVPPLEFQTALPSPGEDEAERSAQLRRNIAGIAQGWKGKHAPAILPLPERIPLLELLQQWDRTSGPSGALPYEVPVGLQSDDLEPFLLNLKEGPNFIVGSPMEGGKTSFLMSWIISLAYYTSPDQMQVYTIDTRYGGGGLSRLRHLPHVKVAAESEEEMGPLVQQVHDIVQQRSKDGNDPELLLVIDDADMLSKQLNDFMIKDQLSAIVRLGRDRNVHVVLSGVPADFPTFGVDWFNDVKASQSGMLFGTLDSNDLSFFRIPYSEANAAAGGLKVLPPGQGYYVRRKFTRIKAAIPFSEQMSCEDWITKIRDRWHVVV
>NZ_CP006872.1|WP_013370783.1|2297631_2297952_+|hypothetical-protein
MILTVLSGRQETEWFDIEVADEYSVEHLKLMLGVRIFGEPPAEGMQYIMEAKFPEGLWFRVEDNQLLTGAGLREGCTVRIQRAFSTTQDEAPVYGRRSLFQTEKNG
>NZ_CP006872.1|WP_013370782.1|2297002_2297242_-|hypothetical-protein
MRTLITFQNKRIPVYFNQENKQPVQKTLKLLSNTLENKISSGKRALQKCLNSLISIEIVGCEAILHSVSENDSLALSLY
>NZ_CP006872.1|WP_025364683.1|2311294_2311609_+|hypothetical-protein
MNLLAIPGLYFYIYLGIGLIVGYRFVSQELTERAQEKRQDNEEENDKELSAAREGLYQSLHDLHRLIGQKGVIATLYILFMLFWLPSWLVITWKRLFTKKTEGD
>NZ_CP006872.1|WP_025364684.1|2311614_2314098_+|CRISPR-associated-helicase/endonuclease-Cas3
MEYIAHIRESNQEIQTVGEHLYETRQLAEVYGDKIGIRHITGLAGMLHDLGKYTEKFQNYIRLAVQNPDNPPKRGSVDHSSAGGKLLYTLFHIQPQGTFDKQDVFIKYVLTEVVANAIISHHSYLQDFLNPQLESRFLYRVRDLDIEGFEDAVVLFYKQVIDKSAFFDYVNQAMAELDQYMKREGEVDFELKLMYLSKFVFSALIDADRTNTRCFEEKKSAGDKTKVEPMHHQKLFHEYYKKLMMHIKSLQAGSDANTPINLLRKEMSEQCEQFAKRLSGIHTLSIPTGGGKTLASFRYALKHAATFEKKHIIYVVPFTTIIEQNVREIRKIILDDANILEHHSNVVVDDHEEEESSEFEDVVVSTRQKLKLAKDNWDSPIIFTTMVQFLNVFYAGGSRNIRRLHNLSESVIIFDEVQKVPTHCISLFNQAVNFLKTYAYSSIVLCTATQPELDFVHNKLAIEPDAEMIHDLDHVIESFKRVDIVDKATDMKFSTEKLGDFVEQKLADEQSVLVILNTKTVVRNLYQRLKEGNGTVPIYHLSTSMCPAHRNSILEEVKNHLKHKKPVICISTQLIEAGVDISFKCVIRSLAGLDSIAQATGRCNRHGEYKKKQVYVIDHEEEDLKRLKEIKIGKEITRKMFIDLKDDKTRFGGNILSAQAMEIYFQKYYSELKTDLNYFIPKLRKNMTELLYANRIENTYYQSYCKENETILPLLLANSYKTAADHFQVIEDHTTAVIVPYGDEEKEGKEIIADLNGQKSIEDLTDLLRRAQQFTINIFNYEKDRLDQNKGLVSFLDGKIYALTDGAYDDCYGLNLENDSLHHEFIL
>NZ_CP006872.1|WP_025364685.1|2314211_2314928_+|type-I-C-CRISPR-associated-protein-Cas5
MRNAIEFKVYGDYALFTDPLTKLGGEKLTYSVPTYQALKGIVESIYWKPTIMMVVDKVRVLHAIRMESKGVRPIEYSGGNTLANYTYLKDPCYEVQAHFEFNPHRPEMEYDRNENKHHNILKRSLLAGGRRDIFLGTRECQAYVEPCVFGIEAGFYDNYGDIHLGNMVHGINYPDETGRDQLEVRLWNPVMKDGVIDFIRPEKCIQVRTIANMQSKQFDTNNVQSADELLAQWEGWGN
>NZ_CP006872.1|WP_017427972.1|2314928_2316836_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLLNLYETYESNLDRVGVIEKKHNDREYTLLPISHTTQNAQIEVEVTEQGDFHSAKILDKNEFSTLIPSTEKSASRAGSVISPYPLHDKLSYVAGDFVAYGGKIKKEEPFAAYIQQLEGWATSDYATSKVKSIYRYLSKRHLIKDLVDNFILYLDEDQKLITTWDKKYEPLHGEKPPIFTAVPGEQESVFIRFNVYSPDKALDKVWEDKEMYDSFVGYYSQLLGEEDICYVTGKQLPSTDKHANKIRNSGDKAKLISANDTSGFTFRGRFAHSHEAASISYEVSQKAHNALKWLINRQGKVIEQRVFLVWGNDEPSILNFTENDNIFAMGLPAKAKEIKSHTNEEFAFEFAKALTGYANTLAVKSSSKAKVNILVLDSATTGRMAVIYYRNLDKKLYFEKLIHWHSTCVWLHRYQKDEQGEYLQFWGAPATKDIAFAAYGSKANDKLVKGLMERMLPCIVDGQNIPQDIVRSAINRASNPVSMDKWEWEKTLSVTCALVNQREGYNVALDKENMDRSYLFGRLLAIADVMERSALDKDEKRSTNATRYMSAFSQHPERTWRTIQNALQPHQARLGKRLSYYTNMIDEVLHKIPFNEFNNKPLTGKYLLGLSSQRYEIYHNSHKKDLEDNNDNK
>NZ_CP006872.1|WP_017427973.1|2316918_2317794_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSVLDHKIDFAVVLSVTKANPNGDPLNGNRPRQNYDGYGEISDVALKRKIRNRLQDMGESIFVQSNDRKSDAFNSLRERADANPELEKFFKGKESSSDEFARIACREWIDVRSFGQVFAFKAAGKGAGVSVGVRGPVSIHTATSIDPIDITSMQITKSVNSEPGKERGSDTMGMKHRVDFGVYLFKGSINTQLAEKTGFTNEDAGKIKDALISLFENDISSARPDGSMEVHKVYWWEHSSKLGQYSSAKVHRSLQVISKENVDESDKYFDTHYECILTPLEGLKVQEYAGL
>NZ_CP006872.1|WP_017427974.1|2317780_2318440_+|CRISPR-associated-protein-Cas4
MQGYNEEDYLLLSGLQHFNFCRRQWALIHIEQQWEENVRTIEGNHLHRKADQPMIREKRGEKLIVRALPIHSRELGITGICDVVEFIRDPHGVPLAGEEGTYLPFPVEYKRGKPKRNDSDHAQLVAQVMCLEEMLVCEISKGYFYYDEIKHRVEVIITAADRERVRASLQEMRHYFERNHTPKAKAGPHCLNCSLHNICVPEILSKKSVSSFIESRIAE
>NZ_CP006872.1|WP_017427975.1|2318436_2319468_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTMPDTYLSLDGENIVIKQEESILARYPLHNLEAVCTFGYSGVSPGLMGACATRNIDLTFMTRSGRFLARVTGESRGNVVLRKEQYRISDDNRRSALVARNMIIGKIYNHKWILERATRDYPLRIDTERMKKVTASLTEIMKQVREVEELDILRGLEGTAAVQYNSVWDDLILQQKDDFYFHGRHKRPPLDNVNALLSFAYTLLSNDMKSALEAVGLDAYVGFLHRDRPGRASLALDVMEELRGVYADRFVLTLINKKLIHGKGFYKKENGAVMMDDDTRKIVLKAWQERKQEKIIHPYLNEKISWGLVPYSQALLLARYIRGDLDEYPPFLWK
>NZ_CP006872.1|WP_025364686.1|2319478_2319769_+|CRISPR-associated-endonuclease-Cas2
MLILITYDVSTVDREGRKRLAKVAKKCVDHGQRVQNSVFECILDSTQFRRLKYELEELIDKTEDSLRFYNLGDNYKKKVEHIGATEAYDMESPLIL
>NZ_CP006872.1|WP_025364687.1|2322409_2323807_+|helix-turn-helix-transcriptional-regulator
MKHTPTISAKFEVYLKQNDMTLSQFVEYSGVHQRTLSNWITQHRPVSVQQLDRITVAMDLLEGYFYDLYIENYIIELSPNFRRIEPLLYRCAELDKLDAIRRMVGHIMDNPLYASRLFDIAEALFNQRRHAAALLLYENVAEVEKYQHSERLAICQYRIFTIQVGDDQGLNLKAATLFEPFVERLDEIDQLDALKDLANVYRSLRLWDRLDVIARKMRDKAEIQYTLEHQQKKRNHAQLEKKLSRPLFVYITYADLLCASVYEAKGDYDQALEYTYAYANLDWVKETDENTLHWIKQFQDWAEGNTYTYKLLSGDISVLNNYVEYIAASPDASEKEMITKLLNIMMAANRYQVDVDDILKQFETEIDSITQQQLSADMYTYQVVPEQSTRFKYELAKYYLNKGNYSLGFEHLLDVLFKSLVINKEAFFISCIKLFEQFKQIADFRLCTRYESLIREGRKERLFYY
>NZ_CP006872.1|WP_019687040.1|2324164_2324332_+|aspartyl-phosphate-phosphatase-Spo0E-family-protein
MLMNPGVTLLRVERARKRLYQVQKKYGFLTHPKVIEQSMKLDELLNQYQTCKMKS

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Crispr_ID: NZ_CP006872_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP006872_2

2319951-2321681

TypeI

Consensus_repeat	Method
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	PILER-CR
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCTGTATGGAGTGCGTGGATTGAAATN	CRT

25 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NZ_CP006872_2

>merge|NZ_CP006872|2|2319951-2321681|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCTGTATGGAGTGCGTGGATTGAAATTGATGGAGACGATCAGGTTAAATCCAAATTGGTCGTCGCACTCTGTATGGAGTGCGTGGATTGAAATGTCGTTCGGCTCAGGATCTACTGGCCCCCAAATAGTCGCACTCTGTATGGAGTGCGTGGATTGAAATACAATGGCGACTATGATTTTACCGATCATATAGAGTCGCACTCTGTATGGAGTGCGTGGATTGAAATTGATTGAGCTTTTTTCTAATCTCTCGCTGCATGTGCGTCGCACTCTGTATGGAGTGCGTGGATTGAAATCAGGTGCCTGACGGTGGTTTCGAGGTGACTATACCGTCGCACTCTGTATGGAGTGCGTGGATTGAAATCAATACCGAAATGATAGGGGGTGGTCAACACGAGTCGCACTCTGTATGGAGTGCGTGGATTGAAATTTGTCATTCGGCGTAGCTTTCAGGTTTTTAATTACGTCGCACTCTGTATGGAGTGCGTGGATTGAAATCTGATCGTACGTGTAACTTGCCGGAAGCTCTGAGGGAGTCGCACTCTGTATGGAGTGCGTGGATTGAAATCGTCTGGCTGCTCAAATTTAACGATCTGAGAATGGTCGCACTCTGTATGGAGTGCGTGGATTGAAATGGACATCATCCCGGAGTAATACAAACAACCCCCGCGTCGCACTCTGTATGGAGTGCGTGGATTGAAATGACTTCGAAAATGCCCATTGCTGGCTGCTTACGAGTCGCACTCTGTATGGAGTGCGTGGATTGAAATTTGTTAAATAAAATAGTTGAGGAGGTTTTATGATGGTCGCACTCTGTATGGAGTGCGTGGATTGAAATCATGAAAAACCTTTCACGGCCTGTCGGTGCTCCGTCGCACTCTGTATGGAGTGCGTGGATTGAAATTTATGCTGAACAGGACTCATGGCGGTTAGATACTTAGTCGCACTCTGTATGGAGTGCGTGGATTGAAATTGCCCGTCTCAGGGCCTCTACAGCGGTTTCCTTAGTCGCACTCTGTATGGAGTGCGTGGATTGAAATCATCCCAAAATAACAGATTTGCTATCAACCCTTCGTGGTCGCACTCTGTATGGAGTGCGTGGATTGAAATTTTTACTTGGTCAGAAGGATAACCGTTTGTATATCGTCGCACTCTGTATGGAGTGCGTGGATTGAAATCGGTACCTACATACTTATCCGTACTCTTCCAATCGGTCGCACTCTGTATGGAGTGCGTGGATTGAAATAATGACATTGCCGCTATAAAAAGTTCCCGTTTTAGTCGCACTCTGTATGGAGTGCGTGGATTGAAATTTGAATCCTCTATCCAAGGTGAAGAATGTTCCGAAGCGTCGCACTCTGTATGGAGTGCGTGGATTGAAATGAGCATAACGGAACGTCCTACACGTTGCAATTCCGTCGCACTCTGTATGGAGTGCGTGGATTGAAATAACTTGTTGTACTCTTCTCTCGCCATCCGTTACACCTGGTCGCACTCTGTATGGAGTGCGTGGATTGAAATAAAGCCCCCTGCATGAGCTGTCCTGCATCCATTCTGTCGCACTCTGTATGGAGTGCGTGGATTGAAATATCGACATGACGAATATAACAAGCATTAGTATATTGTCGCACTCTGTATGGAGTGCGTGGATTGAAATCGCTAGATGGTAAGAAAACTGCTTATGAATTTACGTCGCACTCTATATGAGTGCGTGAATTAAAATA

>NZ_CP006872|2|2|2319951-2321614|PILER-CR
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TGATGGAGACGATCAGGTTAAATCCAAATTGGTC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GTCGTTCGGCTCAGGATCTACTGGCCCCCAAATA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	ACAATGGCGACTATGATTTTACCGATCATATAGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TGATTGAGCTTTTTTCTAATCTCTCGCTGCATGTGC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CAGGTGCCTGACGGTGGTTTCGAGGTGACTATACC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CAATACCGAAATGATAGGGGGTGGTCAACACGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTGTCATTCGGCGTAGCTTTCAGGTTTTTAATTAC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CTGATCGTACGTGTAACTTGCCGGAAGCTCTGAGGGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CGTCTGGCTGCTCAAATTTAACGATCTGAGAATG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GGACATCATCCCGGAGTAATACAAACAACCCCCGC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GACTTCGAAAATGCCCATTGCTGGCTGCTTACGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTGTTAAATAAAATAGTTGAGGAGGTTTTATGATG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CATGAAAAACCTTTCACGGCCTGTCGGTGCTCC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTATGCTGAACAGGACTCATGGCGGTTAGATACTTA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TGCCCGTCTCAGGGCCTCTACAGCGGTTTCCTTA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CATCCCAAAATAACAGATTTGCTATCAACCCTTCGTG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTTTACTTGGTCAGAAGGATAACCGTTTGTATATC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CGGTACCTACATACTTATCCGTACTCTTCCAATCG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	AATGACATTGCCGCTATAAAAAGTTCCCGTTTTA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTGAATCCTCTATCCAAGGTGAAGAATGTTCCGAAGC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GAGCATAACGGAACGTCCTACACGTTGCAATTCC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	AACTTGTTGTACTCTTCTCTCGCCATCCGTTACACCTG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	AAAGCCCCCTGCATGAGCTGTCCTGCATCCATTCT
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	ATCGACATGACGAATATAACAAGCATTAGTATATT
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT

>NZ_CP006872|2|2|2319951-2321614|CRISPRCasFinder
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TGATGGAGACGATCAGGTTAAATCCAAATTGGTC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GTCGTTCGGCTCAGGATCTACTGGCCCCCAAATA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	ACAATGGCGACTATGATTTTACCGATCATATAGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TGATTGAGCTTTTTTCTAATCTCTCGCTGCATGTGC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CAGGTGCCTGACGGTGGTTTCGAGGTGACTATACC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CAATACCGAAATGATAGGGGGTGGTCAACACGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTGTCATTCGGCGTAGCTTTCAGGTTTTTAATTAC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CTGATCGTACGTGTAACTTGCCGGAAGCTCTGAGGGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CGTCTGGCTGCTCAAATTTAACGATCTGAGAATG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GGACATCATCCCGGAGTAATACAAACAACCCCCGC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GACTTCGAAAATGCCCATTGCTGGCTGCTTACGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTGTTAAATAAAATAGTTGAGGAGGTTTTATGATG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CATGAAAAACCTTTCACGGCCTGTCGGTGCTCC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTATGCTGAACAGGACTCATGGCGGTTAGATACTTA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TGCCCGTCTCAGGGCCTCTACAGCGGTTTCCTTA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CATCCCAAAATAACAGATTTGCTATCAACCCTTCGTG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTTTACTTGGTCAGAAGGATAACCGTTTGTATATC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CGGTACCTACATACTTATCCGTACTCTTCCAATCG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	AATGACATTGCCGCTATAAAAAGTTCCCGTTTTA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTGAATCCTCTATCCAAGGTGAAGAATGTTCCGAAGC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GAGCATAACGGAACGTCCTACACGTTGCAATTCC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	AACTTGTTGTACTCTTCTCTCGCCATCCGTTACACCTG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	AAAGCCCCCTGCATGAGCTGTCCTGCATCCATTCT
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	ATCGACATGACGAATATAACAAGCATTAGTATATT
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT

>NZ_CP006872|2|2|2319951-2321681|CRT
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TGATGGAGACGATCAGGTTAAATCCAAATTGGTC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GTCGTTCGGCTCAGGATCTACTGGCCCCCAAATA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	ACAATGGCGACTATGATTTTACCGATCATATAGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TGATTGAGCTTTTTTCTAATCTCTCGCTGCATGTGC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CAGGTGCCTGACGGTGGTTTCGAGGTGACTATACC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CAATACCGAAATGATAGGGGGTGGTCAACACGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTGTCATTCGGCGTAGCTTTCAGGTTTTTAATTAC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CTGATCGTACGTGTAACTTGCCGGAAGCTCTGAGGGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CGTCTGGCTGCTCAAATTTAACGATCTGAGAATG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GGACATCATCCCGGAGTAATACAAACAACCCCCGC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GACTTCGAAAATGCCCATTGCTGGCTGCTTACGA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTGTTAAATAAAATAGTTGAGGAGGTTTTATGATG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CATGAAAAACCTTTCACGGCCTGTCGGTGCTCC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTATGCTGAACAGGACTCATGGCGGTTAGATACTTA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TGCCCGTCTCAGGGCCTCTACAGCGGTTTCCTTA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CATCCCAAAATAACAGATTTGCTATCAACCCTTCGTG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTTTACTTGGTCAGAAGGATAACCGTTTGTATATC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CGGTACCTACATACTTATCCGTACTCTTCCAATCG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	AATGACATTGCCGCTATAAAAAGTTCCCGTTTTA
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	TTGAATCCTCTATCCAAGGTGAAGAATGTTCCGAAGC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	GAGCATAACGGAACGTCCTACACGTTGCAATTCC
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	AACTTGTTGTACTCTTCTCTCGCCATCCGTTACACCTG
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	AAAGCCCCCTGCATGAGCTGTCCTGCATCCATTCT
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	ATCGACATGACGAATATAACAAGCATTAGTATATT
GTCGCACTCTGTATGGAGTGCGTGGATTGAAAT	CGCTAGATGGTAAGAAAACTGCTTATGAATTTAC
GTCGCACTCTATATGAGTGCGTGAATTAAAATA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP006872.1\|WP_017427972.1\|2314928_2316836_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NZ_CP006872.1\|WP_025364683.1\|2311294_2311609_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP006872.1\|WP_025364686.1\|2319478_2319769_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NZ_CP006872.1\|WP_025364684.1\|2311614_2314098_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NZ_CP006872.1\|WP_019687040.1\|2324164_2324332_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	unknown	unknown	gnl\|CDD\|378175
NZ_CP006872.1\|WP_025364691.1\|2333031_2333601_-\|conjugal-transfer-protein-TraR	unknown	unknown	gnl\|CDD\|274340
NZ_CP006872.1\|WP_017428324.1\|2329184_2329769_+\|low-temperature-induced-protein	unknown	unknown	gnl\|CDD\|378584
NZ_CP006872.1\|WP_080690723.1\|2325180_2326176_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NZ_CP006872.1\|WP_025364690.1\|2330038_2331211_+\|acyltransferase	unknown	unknown	gnl\|CDD\|376607
NZ_CP006872.1\|WP_017427973.1\|2316918_2317794_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|226175
NZ_CP006872.1\|WP_013310011.1\|2331529_2331892_+\|replication-termination-protein	unknown	unknown	gnl\|CDD\|376766
NZ_CP006872.1\|WP_017428326.1\|2331911_2332916_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NZ_CP006872.1\|WP_025364688.1\|2324741_2325116_+\|DUF1992-domain-containing-protein	unknown	unknown	gnl\|CDD\|182303
NZ_CP006872.1\|WP_017427975.1\|2318436_2319468_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NZ_CP006872.1\|WP_017427974.1\|2317780_2318440_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NZ_CP006872.1\|WP_025364685.1\|2314211_2314928_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NZ_CP006872.1\|WP_025364687.1\|2322409_2323807_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NZ_CP006872.1\|WP_017427968.1\|2308148_2308958_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NZ_CP006872.1\|WP_025364682.1\|2307046_2307883_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238083
NZ_CP006872.1\|WP_019687041.1\|2324432_2324627_+\|Rha-family-transcriptional-regulator	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP006872.1\|WP_017427972.1\|2314928_2316836_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	1.75598e-168
NZ_CP006872.1\|WP_025364686.1\|2319478_2319769_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.26636e-30
NZ_CP006872.1\|WP_019687040.1\|2324164_2324332_+\|aspartyl-phosphate-phosphatase-Spo0E-family-protein	gnl\|CDD\|378175	pfam09388, SpoOE-like, Spo0E like sporulation regulatory protein. Spore formation is an extreme response to starvation and can also be a component of disease transmission. Sporulation is controlled by an expanded two-component system where starvation signals result in sensor kinase activation and phosphorylation of the master sporulation response regulator Spo0A. Phosphatases such as Spo0E dephosphorylate Spo0A thereby inhibiting sporulation. This is a family of Spo0E-like phosphatases. The structure of a Bacillus anthracis member of this family has revealed an anti-parallel alpha-helical structure.	5.35762e-08
NZ_CP006872.1\|WP_025364691.1\|2333031_2333601_-\|conjugal-transfer-protein-TraR	gnl\|CDD\|274340	TIGR02890, conserved_hypothetical_protein, regulatory protein, yteA family. Members of this predicted regulatory protein are found only in endospore-forming members of the Firmicutes group of bacteria, and in nearly every such species; Clostridium perfringens seems to be an exception. The member from Bacillus subtilis, the model system for the study of the sporulation program, has been designated both yteA and yzwB. Some (but not all) members of this family show a strong sequence match to Pfam family pfam01258 the C4-type zinc finger protein, DksA/TraR family, but only one of the four key Cys residues is conserved. All members of this protein family share an additional C-terminal domain. Smaller proteins from the proteobacteria with just the N-terminal domain, including DksA and DksA2 are RNA polymerase-binding regulatory proteins even if the Zn-binding site is not conserved. [Unknown function, General].	2.87784e-52
NZ_CP006872.1\|WP_017428324.1\|2329184_2329769_+\|low-temperature-induced-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	1.37487e-12
NZ_CP006872.1\|WP_080690723.1\|2325180_2326176_-\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	2.57438e-114
NZ_CP006872.1\|WP_025364690.1\|2330038_2331211_+\|acyltransferase	gnl\|CDD\|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	6.99462e-18
NZ_CP006872.1\|WP_017427973.1\|2316918_2317794_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|226175	COG3649, COG3649, CRISPR system related protein [Defense mechanisms].	4.97551e-130
NZ_CP006872.1\|WP_013310011.1\|2331529_2331892_+\|replication-termination-protein	gnl\|CDD\|376766	pfam02334, RTP, Replication terminator protein. The bacterial replication terminator protein (RTP) plays a role in the termination of DNA replication by impeding replication fork movement. Two RTP dimers bind to the two inverted repeat regions at the termination site.	1.76322e-55
NZ_CP006872.1\|WP_017428326.1\|2331911_2332916_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.47822e-83
NZ_CP006872.1\|WP_017427968.1\|2308148_2308958_+\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	6.24113e-90
NZ_CP006872.1\|WP_025364688.1\|2324741_2325116_+\|DUF1992-domain-containing-protein	gnl\|CDD\|182303	PRK10203, PRK10203, hypothetical protein; Provisional.	1.422e-31
NZ_CP006872.1\|WP_017427975.1\|2318436_2319468_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NZ_CP006872.1\|WP_017427974.1\|2317780_2318440_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	3.21027e-27
NZ_CP006872.1\|WP_025364685.1\|2314211_2314928_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	9.0233e-94
NZ_CP006872.1\|WP_025364687.1\|2322409_2323807_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	0.00935747
NZ_CP006872.1\|WP_025364684.1\|2311614_2314098_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.39476e-71
NZ_CP006872.1\|WP_025364682.1\|2307046_2307883_+\|hypothetical-protein	gnl\|CDD\|238083	cd00143, PP2Cc, Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence similarity.	0.0025833

>NZ_CP006872.1|WP_025364686.1|2319478_2319769_+|CRISPR-associated-endonuclease-Cas2
MLILITYDVSTVDREGRKRLAKVAKKCVDHGQRVQNSVFECILDSTQFRRLKYELEELIDKTEDSLRFYNLGDNYKKKVEHIGATEAYDMESPLIL
>NZ_CP006872.1|WP_017427975.1|2318436_2319468_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTMPDTYLSLDGENIVIKQEESILARYPLHNLEAVCTFGYSGVSPGLMGACATRNIDLTFMTRSGRFLARVTGESRGNVVLRKEQYRISDDNRRSALVARNMIIGKIYNHKWILERATRDYPLRIDTERMKKVTASLTEIMKQVREVEELDILRGLEGTAAVQYNSVWDDLILQQKDDFYFHGRHKRPPLDNVNALLSFAYTLLSNDMKSALEAVGLDAYVGFLHRDRPGRASLALDVMEELRGVYADRFVLTLINKKLIHGKGFYKKENGAVMMDDDTRKIVLKAWQERKQEKIIHPYLNEKISWGLVPYSQALLLARYIRGDLDEYPPFLWK
>NZ_CP006872.1|WP_017427974.1|2317780_2318440_+|CRISPR-associated-protein-Cas4
MQGYNEEDYLLLSGLQHFNFCRRQWALIHIEQQWEENVRTIEGNHLHRKADQPMIREKRGEKLIVRALPIHSRELGITGICDVVEFIRDPHGVPLAGEEGTYLPFPVEYKRGKPKRNDSDHAQLVAQVMCLEEMLVCEISKGYFYYDEIKHRVEVIITAADRERVRASLQEMRHYFERNHTPKAKAGPHCLNCSLHNICVPEILSKKSVSSFIESRIAE
>NZ_CP006872.1|WP_017427973.1|2316918_2317794_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MSVLDHKIDFAVVLSVTKANPNGDPLNGNRPRQNYDGYGEISDVALKRKIRNRLQDMGESIFVQSNDRKSDAFNSLRERADANPELEKFFKGKESSSDEFARIACREWIDVRSFGQVFAFKAAGKGAGVSVGVRGPVSIHTATSIDPIDITSMQITKSVNSEPGKERGSDTMGMKHRVDFGVYLFKGSINTQLAEKTGFTNEDAGKIKDALISLFENDISSARPDGSMEVHKVYWWEHSSKLGQYSSAKVHRSLQVISKENVDESDKYFDTHYECILTPLEGLKVQEYAGL
>NZ_CP006872.1|WP_017427972.1|2314928_2316836_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLLNLYETYESNLDRVGVIEKKHNDREYTLLPISHTTQNAQIEVEVTEQGDFHSAKILDKNEFSTLIPSTEKSASRAGSVISPYPLHDKLSYVAGDFVAYGGKIKKEEPFAAYIQQLEGWATSDYATSKVKSIYRYLSKRHLIKDLVDNFILYLDEDQKLITTWDKKYEPLHGEKPPIFTAVPGEQESVFIRFNVYSPDKALDKVWEDKEMYDSFVGYYSQLLGEEDICYVTGKQLPSTDKHANKIRNSGDKAKLISANDTSGFTFRGRFAHSHEAASISYEVSQKAHNALKWLINRQGKVIEQRVFLVWGNDEPSILNFTENDNIFAMGLPAKAKEIKSHTNEEFAFEFAKALTGYANTLAVKSSSKAKVNILVLDSATTGRMAVIYYRNLDKKLYFEKLIHWHSTCVWLHRYQKDEQGEYLQFWGAPATKDIAFAAYGSKANDKLVKGLMERMLPCIVDGQNIPQDIVRSAINRASNPVSMDKWEWEKTLSVTCALVNQREGYNVALDKENMDRSYLFGRLLAIADVMERSALDKDEKRSTNATRYMSAFSQHPERTWRTIQNALQPHQARLGKRLSYYTNMIDEVLHKIPFNEFNNKPLTGKYLLGLSSQRYEIYHNSHKKDLEDNNDNK
>NZ_CP006872.1|WP_025364685.1|2314211_2314928_+|type-I-C-CRISPR-associated-protein-Cas5
MRNAIEFKVYGDYALFTDPLTKLGGEKLTYSVPTYQALKGIVESIYWKPTIMMVVDKVRVLHAIRMESKGVRPIEYSGGNTLANYTYLKDPCYEVQAHFEFNPHRPEMEYDRNENKHHNILKRSLLAGGRRDIFLGTRECQAYVEPCVFGIEAGFYDNYGDIHLGNMVHGINYPDETGRDQLEVRLWNPVMKDGVIDFIRPEKCIQVRTIANMQSKQFDTNNVQSADELLAQWEGWGN
>NZ_CP006872.1|WP_025364684.1|2311614_2314098_+|CRISPR-associated-helicase/endonuclease-Cas3
MEYIAHIRESNQEIQTVGEHLYETRQLAEVYGDKIGIRHITGLAGMLHDLGKYTEKFQNYIRLAVQNPDNPPKRGSVDHSSAGGKLLYTLFHIQPQGTFDKQDVFIKYVLTEVVANAIISHHSYLQDFLNPQLESRFLYRVRDLDIEGFEDAVVLFYKQVIDKSAFFDYVNQAMAELDQYMKREGEVDFELKLMYLSKFVFSALIDADRTNTRCFEEKKSAGDKTKVEPMHHQKLFHEYYKKLMMHIKSLQAGSDANTPINLLRKEMSEQCEQFAKRLSGIHTLSIPTGGGKTLASFRYALKHAATFEKKHIIYVVPFTTIIEQNVREIRKIILDDANILEHHSNVVVDDHEEEESSEFEDVVVSTRQKLKLAKDNWDSPIIFTTMVQFLNVFYAGGSRNIRRLHNLSESVIIFDEVQKVPTHCISLFNQAVNFLKTYAYSSIVLCTATQPELDFVHNKLAIEPDAEMIHDLDHVIESFKRVDIVDKATDMKFSTEKLGDFVEQKLADEQSVLVILNTKTVVRNLYQRLKEGNGTVPIYHLSTSMCPAHRNSILEEVKNHLKHKKPVICISTQLIEAGVDISFKCVIRSLAGLDSIAQATGRCNRHGEYKKKQVYVIDHEEEDLKRLKEIKIGKEITRKMFIDLKDDKTRFGGNILSAQAMEIYFQKYYSELKTDLNYFIPKLRKNMTELLYANRIENTYYQSYCKENETILPLLLANSYKTAADHFQVIEDHTTAVIVPYGDEEKEGKEIIADLNGQKSIEDLTDLLRRAQQFTINIFNYEKDRLDQNKGLVSFLDGKIYALTDGAYDDCYGLNLENDSLHHEFIL
>NZ_CP006872.1|WP_025364683.1|2311294_2311609_+|hypothetical-protein
MNLLAIPGLYFYIYLGIGLIVGYRFVSQELTERAQEKRQDNEEENDKELSAAREGLYQSLHDLHRLIGQKGVIATLYILFMLFWLPSWLVITWKRLFTKKTEGD
>NZ_CP006872.1|WP_017427968.1|2308148_2308958_+|SDR-family-oxidoreductase
MSYTYAGGARFEGKTALITGAGSGIGKATAIQMAREGANVALFDVSNDRILETEREINAIREGSARAFDVDIADPVRVEKAVLEAVELFGGLHIIFANAGINGVVGPIEELSIEDWRQTLSTNLDGTFLTVKYTIPHLKKNGGGSIIITSSINGNQRFTSFGMSAYSTSKAGQTGFAKMAALELAKFRIRVNVIYPGAISTNIDETTEKSEGLKQITIPVQFPEGDQPLADGPGQPEQVADLVTFLASDHSRHITGAQIVIDGAESLLF
>NZ_CP006872.1|WP_025364682.1|2307046_2307883_+|hypothetical-protein
MNPLLSLLPTSKKKGLNARLTQQFAYISSQTGDQPLSSHHSRFMCRYGYGRSAESASMGESGQDFAAVRIHKSVCCFVLCDGVGLSYRGDFAARYLGSSLLDWMEQRQDLSANQLREYLERLAGAATEELDRQPLDHESGLMRSVLEDKRRQGSQSMYICGKIELPKRGTRGRLRLAWQGDSRLRLWNGTEEISELFNHTFSTAERWSTSRGPIGGKPHWYERSIPADMPMRLQVYTDGLSDLDPIREPVPDEQIQVLLDASHTGGLDDDAAFIELQW
>NZ_CP006872.1|WP_025364687.1|2322409_2323807_+|helix-turn-helix-transcriptional-regulator
MKHTPTISAKFEVYLKQNDMTLSQFVEYSGVHQRTLSNWITQHRPVSVQQLDRITVAMDLLEGYFYDLYIENYIIELSPNFRRIEPLLYRCAELDKLDAIRRMVGHIMDNPLYASRLFDIAEALFNQRRHAAALLLYENVAEVEKYQHSERLAICQYRIFTIQVGDDQGLNLKAATLFEPFVERLDEIDQLDALKDLANVYRSLRLWDRLDVIARKMRDKAEIQYTLEHQQKKRNHAQLEKKLSRPLFVYITYADLLCASVYEAKGDYDQALEYTYAYANLDWVKETDENTLHWIKQFQDWAEGNTYTYKLLSGDISVLNNYVEYIAASPDASEKEMITKLLNIMMAANRYQVDVDDILKQFETEIDSITQQQLSADMYTYQVVPEQSTRFKYELAKYYLNKGNYSLGFEHLLDVLFKSLVINKEAFFISCIKLFEQFKQIADFRLCTRYESLIREGRKERLFYY
>NZ_CP006872.1|WP_019687040.1|2324164_2324332_+|aspartyl-phosphate-phosphatase-Spo0E-family-protein
MLMNPGVTLLRVERARKRLYQVQKKYGFLTHPKVIEQSMKLDELLNQYQTCKMKS
>NZ_CP006872.1|WP_019687041.1|2324432_2324627_+|Rha-family-transcriptional-regulator
MNKRNPVTPFGWKIKQKLVEIQMDQRTFCDTYHIPASRLSNLIHGTRKAKKYRKQVCQLLRIEE
>NZ_CP006872.1|WP_025364688.1|2324741_2325116_+|DUF1992-domain-containing-protein
MRMFSRMAEQKIAEAMAKGEFDHLPGEGKPLVIEDLSHVPEELRMSYKLLKNAGILPEELQLQKECVQLRDLLHACHEAGEQQRISRRLTEKSLRLRMLLEERGLNMSSVFYEYESAVRQRLEE
>NZ_CP006872.1|WP_080690723.1|2325180_2326176_-|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MELQTQPIRGRFAPTPSGRIHLGNARTALLSWLHVRSLGGTYILRMEDIDMTRACSALAQGIMEDLRWIGLDWDEGPDIGGPYGPYSQSQRLERFQSALEKLQGQDLLYPCFCSRADIMAAAHAPHGLSGEGPAYSGTCRNLSSSEALAKAQHKLPSLRFKVPQHSDDIISFHDQVAGHVSFRASEGGDFIIKRADGMFSYQLAVVVDDANMHMTDVLRGYDLLDSTPRQLLLYQALGLVPPRFAHVPLVLGPDGRRLAKRHGGVALRAMRRQGITPEAVIGWLAYFSGLLDSPEPVKAVDLIDGFHLDKLPRGPVLLTKQCLTKLSALQQ
>NZ_CP006872.1|WP_017428324.1|2329184_2329769_+|low-temperature-induced-protein
MANNLNDYNEKKIVGVFDTEQEASRAIGQLQSKGIPSSEISVITRDRDDLRTISEETGTKAPEGVATGAATGGVVGGVAGLLAGIGALAIPGIGPILAAGPIAATLTGAAVGAGAGGLVGGLVGLGIPEDDARQYETYVDQGKILVLVDSADHHRDVYDIFRTNRSLNADRYRTYDDTVADSRTGAYTDTRRNL
>NZ_CP006872.1|WP_025364690.1|2330038_2331211_+|acyltransferase
MSQKERISEVALLRGLAFAAVVLQHSVAHYAVAQGARIQDGVVMTLLLLCAKFAVPVFVFITGMVLFYNYDGALKYGTFLRKRFMDIIVPYIIWSLLYELGNQLAQGGELIHPLDFVQKLLNGKSSYHLWYIVMIIQCYVLFPVFRYAVRRLSALLPSTWRPTALAGFGVLYILLMFAVGPVYQVMDQLQLPVISSWFTIYADRNVIYFFFYFILGAAAGMNIKRWNAWVIKAQLVYWPLFIVITGYLLYEMIGQFQTPQGTVLSFNYLSLLRPVMAVYCITSIFVAYRIATWIAHKGGRAARVLTAIGTLSYGAYLMHAFMLRATYYFDSALFADWSHVLRTLASFVLCMIFSIAGTWVLAHLPLGKWIVGLRIRPRPAGSPPAIQKQA
>NZ_CP006872.1|WP_013310011.1|2331529_2331892_+|replication-termination-protein
MAFMISQRAFIKIYLITMVERHRGYGYQMLESMKDEFSGFGYVPPQSEVYRALHELVQEGVFYRTKRLKGTDPRVDFQEIVLYHFTDDGEEKARLYKKQVKADLDRCLGMLHKAEQDNYS
>NZ_CP006872.1|WP_017428326.1|2331911_2332916_+|Gfo/Idh/MocA-family-oxidoreductase
MGRKLKWGILGTAEIAKIAVIPAIQQSERGEVLGIASRNADKATEAAREFDIPRSYGSYDELLADPEIGAVYIPLPNHLHEEWTIKAAEAGKHVLCEKPSSLSSAGTSRMIEACRRAGVTFAEAFMYRYHPKHRRIKEIINSGEIGDIRGIHCTFTFNNTDQADNVRFNKSMGGGSLYDVGVYPISAARMYLDREPEAVTVHALFSPEHDNVDMMASGLLEFPGGVNLTFDCGMWAANRSNMEILGSKGTIAMPKMFGWERTSVVPQIFVHVGSVTREERLKGFNSFELQADAFAKAVLDGIPLPYEPEDAVSNMKVIDACIESARSRKRIEIG
>NZ_CP006872.1|WP_025364691.1|2333031_2333601_-|conjugal-transfer-protein-TraR
MNHLNDSQLAELKHMLLEQKKDLEKHFKQNGQENTKLGETLTDSTGELSSYDNHPADIGTETFERSRDLAINESLENELEQVNAALQRMEDGTYGRCVESGEEIPFERLQAIPYTAYTVEHTPTRELSNDRPIEEQVMTPPPKGAGEVRQRNAGRFDDAGAWDAVEKYGTSNSPATAAKRDVTDYDENM

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP006872_2	2.12\|2320728\|35\|NZ_CP006872\|PILER-CR,CRISPRCasFinder,CRT	2320728-2320762	35	NC_014628	Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence	229680-229714	0	1.0
NZ_CP006872_1	1.7\|2309637\|36\|NZ_CP006872\|PILER-CR,CRISPRCasFinder,CRT	2309637-2309672	36	NC_014628	Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence	422800-422835	1	0.972
NZ_CP006872_1	1.10\|2309836\|36\|NZ_CP006872\|PILER-CR,CRISPRCasFinder,CRT	2309836-2309871	36	NC_014628	Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence	422800-422835	1	0.972
NZ_CP006872_1	1.5\|2309506\|33\|NZ_CP006872\|PILER-CR,CRISPRCasFinder,CRT	2309506-2309538	33	KY197768	Bacillus phage phi105 N-acetylmuramoyl-L-alanine amidase CwlH gene, complete cds	34557-34589	6	0.818
NZ_CP006872_1	1.18\|2310370\|34\|NZ_CP006872\|PILER-CR,CRISPRCasFinder,CRT	2310370-2310403	34	MF417893	Uncultured Caudovirales phage clone 9AX_2, partial genome	27020-27053	9	0.735
NZ_CP006872_2	2.12\|2320728\|35\|NZ_CP006872\|PILER-CR,CRISPRCasFinder,CRT	2320728-2320762	35	NC_023287	Exiguobacterium sp. S3-2 plasmid pMC1, complete sequence	33485-33519	9	0.743
NZ_CP006872_2	2.25\|2321615\|34\|NZ_CP006872\|CRT	2321615-2321648	34	MH319731	Marine virus AG-345-E02 Ga0172268_11 genomic sequence	76824-76857	9	0.735
NZ_CP006872_2	2.25\|2321615\|34\|NZ_CP006872\|CRT	2321615-2321648	34	HQ632825	Prochlorococcus phage P-SSM5 genomic sequence	192770-192803	9	0.735
NZ_CP006872_2	2.25\|2321615\|34\|NZ_CP006872\|CRT	2321615-2321648	34	AY939844	Prochlorococcus phage P-SSM2, complete genome	146563-146596	9	0.735
NZ_CP006872_2	2.25\|2321615\|34\|NZ_CP006872\|CRT	2321615-2321648	34	MT774381	CrAssphage cr3_1, complete genome	1355-1388	9	0.735

1. spacer 2.12|2320728|35|NZ_CP006872|PILER-CR,CRISPRCasFinder,CRT matches to NC_014628 (Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence) position: , mismatch: 0, identity: 1.0

ttgttaaataaaatagttgaggaggttttatgatg	CRISPR spacer
ttgttaaataaaatagttgaggaggttttatgatg	Protospacer
***********************************

2. spacer 1.7|2309637|36|NZ_CP006872|PILER-CR,CRISPRCasFinder,CRT matches to NC_014628 (Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence) position: , mismatch: 1, identity: 0.972

ataacacaaacaacaaaagactggtctttaatagac	CRISPR spacer
ataacacaaacaacaaaagactggtctttaataaac	Protospacer
*********************************.**

3. spacer 1.10|2309836|36|NZ_CP006872|PILER-CR,CRISPRCasFinder,CRT matches to NC_014628 (Paenibacillus polymyxa SC2 plasmid pSC2, complete sequence) position: , mismatch: 1, identity: 0.972

ataacacaaacaacaaaagactggtctttaatagac	CRISPR spacer
ataacacaaacaacaaaagactggtctttaataaac	Protospacer
*********************************.**

4. spacer 1.5|2309506|33|NZ_CP006872|PILER-CR,CRISPRCasFinder,CRT matches to KY197768 (Bacillus phage phi105 N-acetylmuramoyl-L-alanine amidase CwlH gene, complete cds) position: , mismatch: 6, identity: 0.818

tacctaactgggagaagcatcaaaatgtagatg	CRISPR spacer
ttagcaactgggagaagcaccaaaatgttgatg	Protospacer
*   .**************.******** ****

5. spacer 1.18|2310370|34|NZ_CP006872|PILER-CR,CRISPRCasFinder,CRT matches to MF417893 (Uncultured Caudovirales phage clone 9AX_2, partial genome) position: , mismatch: 9, identity: 0.735

ccgaaacaaaggaaaaatactcaaaattcattga	CRISPR spacer
aggaaactaaggaaaattactcaaaaggaattag	Protospacer
  ***** ******** *********   ***..

6. spacer 2.12|2320728|35|NZ_CP006872|PILER-CR,CRISPRCasFinder,CRT matches to NC_023287 (Exiguobacterium sp. S3-2 plasmid pMC1, complete sequence) position: , mismatch: 9, identity: 0.743

ttgttaaataaaatagttgaggaggttttatgatg-	CRISPR spacer
aaattaaatcaaatagttgaggagatttca-aatat	Protospacer
  .****** **************.***.* .**.

7. spacer 2.25|2321615|34|NZ_CP006872|CRT matches to MH319731 (Marine virus AG-345-E02 Ga0172268_11 genomic sequence) position: , mismatch: 9, identity: 0.735

cgctagatggtaagaaaactgcttatgaatttac	CRISPR spacer
tccattctgttaagaaaactgctaatgaatttaa	Protospacer
. *    ** ************* *********

8. spacer 2.25|2321615|34|NZ_CP006872|CRT matches to HQ632825 (Prochlorococcus phage P-SSM5 genomic sequence) position: , mismatch: 9, identity: 0.735

cgctagatggtaagaaaactgcttatgaatttac	CRISPR spacer
tccattctgttaagaaaactgctaatgaatttaa	Protospacer
. *    ** ************* *********

9. spacer 2.25|2321615|34|NZ_CP006872|CRT matches to AY939844 (Prochlorococcus phage P-SSM2, complete genome) position: , mismatch: 9, identity: 0.735

cgctagatggtaagaaaactgcttatgaatttac	CRISPR spacer
tccattctgttaagaaaactgctaatgaatttaa	Protospacer
. *    ** ************* *********

10. spacer 2.25|2321615|34|NZ_CP006872|CRT matches to MT774381 (CrAssphage cr3_1, complete genome) position: , mismatch: 9, identity: 0.735

-cgctagatggtaagaaaactgcttatgaatttac	CRISPR spacer
ttgctcagc-ctaagaaaactgattatggatttac	Protospacer
 .*** ...  *********** *****.******

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

913069 : 924553

Mollivirus(25.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016819766.1\|913069_914368_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	7.0e-20	33.1
WP_158442522.1\|914626_914776_-	hypothetical protein	NA	NA	NA	NA
WP_019686168.1\|914943_915825_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	1.3e-41	35.0
WP_007428837.1\|915883_916129_+	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FJ99	Synechococcus_phage	1.4e-06	37.7
WP_016819768.1\|916133_916823_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_025364048.1\|916800_919044_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.7e-165	42.4
WP_017426172.1\|919028_920510_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.9e-52	31.6
WP_016819771.1\|921223_922264_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.5e-70	45.8
WP_017426174.1\|922263_922878_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.7e-21	36.4
WP_025364049.1\|923008_924553_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	9.0e-75	52.5

DBSCAN-SWA_2

1296320 : 1313627

Bacillus_phage(42.86%)

portal,plate,holin,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025364223.1\|1296320_1298228_-	LysM peptidoglycan-binding domain-containing protein	A0A2P1CFA9	Microbacterium_phage	5.8e-07	55.6
WP_017426406.1\|1298423_1298849_-	ImmA/IrrE family metallo-endopeptidase	A0A0S2SXM3	Bacillus_phage	3.4e-16	37.2
WP_013369769.1\|1298860_1299334_-	helix-turn-helix domain-containing protein	S6C481	Thermus_phage	3.7e-19	39.7
WP_017426408.1\|1299609_1300086_+	transcriptional regulator	A0A0C5AJ96	Bacteriophage	4.0e-42	62.7
WP_025364224.1\|1300204_1301059_+	aminoglycoside 6-adenylyltransferase	E4ZFP8	Streptococcus_phage	2.6e-87	53.2
WP_025364225.1\|1301404_1302373_+	hypothetical protein	NA	NA	NA	NA
WP_016821321.1\|1302383_1302602_+	hypothetical protein	NA	NA	NA	NA
WP_025364226.1\|1302604_1304071_+\|portal	phage portal protein	A0A0N7AEC6	Bacillus_phage	2.0e-71	35.8
WP_016821317.1\|1304193_1304601_+\|tail	phage tail tube protein	A0A2H4J032	uncultured_Caudovirales_phage	1.5e-40	61.8
WP_007429164.1\|1304701_1305136_+	hypothetical protein	A0A2H4J883	uncultured_Caudovirales_phage	1.8e-20	42.0
WP_025364227.1\|1307071_1307713_+	LysM peptidoglycan-binding domain-containing protein	A0A0N7ACF7	Bacillus_phage	2.9e-43	52.3
WP_025364228.1\|1307709_1308687_+	hypothetical protein	A0A0N6W8H4	Bacillus_phage	6.5e-79	47.7
WP_019686372.1\|1308679_1309087_+	hypothetical protein	A0A0N7ACD3	Bacillus_phage	3.9e-09	32.3
WP_016821304.1\|1309073_1309544_+	DUF2634 domain-containing protein	A0A0N7ACH4	Bacillus_phage	2.6e-25	38.6
WP_016821302.1\|1309543_1310695_+\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	1.7e-41	34.9
WP_019686375.1\|1310687_1311581_+	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_025364230.1\|1311624_1312014_+	hypothetical protein	NA	NA	NA	NA
WP_025364231.1\|1312029_1313049_+\|tail	tail fiber protein	NA	NA	NA	NA
WP_016821295.1\|1313180_1313627_+\|holin	phage holin family protein	R9TMD4	Paenibacillus_phage	8.7e-39	62.2

DBSCAN-SWA_3

1664966 : 1724054

Paenibacillus_phage(28.57%)

tRNA,tail,head,protease,holin,portal,capsid,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025364390.1\|1664966_1665680_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_016820572.1\|1665724_1666897_-	UDP-N-acetylglucosamine--LPS N-acetylglucosamine transferase	NA	NA	NA	NA
WP_013370069.1\|1666909_1667437_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_017426627.1\|1668040_1669279_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_007429515.1\|1669599_1670097_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.1e-16	38.2
WP_007429516.1\|1670117_1670318_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_007429517.1\|1670370_1670730_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_016820568.1\|1671097_1672135_+	BMP family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_025364391.1\|1672272_1673811_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	4.9e-12	26.6
WP_016820564.1\|1673803_1674883_+	ABC transporter permease	NA	NA	NA	NA
WP_010349245.1\|1674884_1675844_+	ABC transporter permease	NA	NA	NA	NA
WP_017426630.1\|1676103_1676454_+	hypothetical protein	NA	NA	NA	NA
WP_016820557.1\|1676488_1676929_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_016820554.1\|1677542_1679288_+	biosynthetic-type acetolactate synthase large subunit	E5ERI2	Ostreococcus_lucimarinus_virus	2.5e-49	29.0
WP_016820552.1\|1679289_1679775_+	acetolactate synthase small subunit	NA	NA	NA	NA
WP_013309387.1\|1679937_1680930_+	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_025364392.1\|1681054_1682596_+	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	7.8e-10	42.3
WP_025364393.1\|1682800_1683877_+	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_013370083.1\|1684197_1684737_+	peroxiredoxin	NA	NA	NA	NA
WP_016820546.1\|1684997_1685414_+	hypothetical protein	NA	NA	NA	NA
WP_019686642.1\|1685751_1686855_+	PAS domain-containing protein	NA	NA	NA	NA
WP_025364394.1\|1687196_1689338_+	EAL domain-containing protein	NA	NA	NA	NA
WP_025364395.1\|1690941_1691415_-	ImmA/IrrE family metallo-endopeptidase	A0A0K2CZC9	Paenibacillus_phage	3.1e-34	51.4
WP_019686646.1\|1691419_1691821_-	helix-turn-helix domain-containing protein	A0A0K2CZS1	Paenibacillus_phage	1.6e-12	27.0
WP_029514935.1\|1691962_1692181_+	helix-turn-helix transcriptional regulator	A0A0K2CZL1	Paenibacillus_phage	1.1e-13	59.4
WP_019686648.1\|1692300_1692579_+	excisionase family DNA-binding protein	NA	NA	NA	NA
WP_025364396.1\|1692683_1693439_+	hypothetical protein	A0A1B1P7T7	Bacillus_phage	6.2e-37	55.4
WP_158442525.1\|1693454_1693610_+	hypothetical protein	NA	NA	NA	NA
WP_025364397.1\|1693623_1693965_+	hypothetical protein	NA	NA	NA	NA
WP_115293095.1\|1694070_1694466_+	hypothetical protein	A0A0K2CYI4	Paenibacillus_phage	5.7e-34	53.5
WP_025364398.1\|1694856_1695711_+	DnaD domain protein	A0A0K2CZ53	Paenibacillus_phage	3.6e-81	65.9
WP_151259613.1\|1695839_1696127_+	hypothetical protein	NA	NA	NA	NA
WP_051517950.1\|1696733_1697141_+	hypothetical protein	NA	NA	NA	NA
WP_025364400.1\|1697171_1697879_+	hypothetical protein	A0A0S2MVI5	Bacillus_phage	3.9e-65	51.9
WP_025364401.1\|1697929_1698232_+	hypothetical protein	NA	NA	NA	NA
WP_051517975.1\|1698251_1698434_+	hypothetical protein	NA	NA	NA	NA
WP_025364403.1\|1698461_1698683_+	hypothetical protein	NA	NA	NA	NA
WP_158442526.1\|1698735_1699050_+	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_025364404.1\|1698931_1699579_+	hypothetical protein	R9TLQ8	Paenibacillus_phage	1.1e-106	82.8
WP_025364405.1\|1699623_1699905_+	hypothetical protein	A0A1B1P779	Bacillus_phage	4.0e-21	55.8
WP_025364406.1\|1699953_1700166_+	hypothetical protein	NA	NA	NA	NA
WP_051517951.1\|1700168_1700438_+	hypothetical protein	NA	NA	NA	NA
WP_025364407.1\|1700527_1700827_+	hypothetical protein	NA	NA	NA	NA
WP_025364408.1\|1700872_1701088_+	hypothetical protein	NA	NA	NA	NA
WP_025364409.1\|1701137_1701362_+	hypothetical protein	NA	NA	NA	NA
WP_039268906.1\|1701364_1701643_+	hypothetical protein	NA	NA	NA	NA
WP_025364411.1\|1701732_1702275_+	RNA polymerase subunit sigma-24	S5MAA9	Brevibacillus_phage	1.5e-37	54.6
WP_025364412.1\|1702382_1702640_+	hypothetical protein	NA	NA	NA	NA
WP_025364413.1\|1702713_1703121_-	hypothetical protein	A0A0C5ABG6	Paenibacillus_phage	2.0e-42	60.6
WP_019686665.1\|1703230_1703446_-	type II toxin-antitoxin system HicA family toxin	A0A0C5AED5	Paenibacillus_phage	3.0e-21	69.0
WP_025364414.1\|1703546_1703876_+	HNH endonuclease	A0A2I7SC48	Paenibacillus_phage	1.8e-25	60.9
WP_025364415.1\|1704041_1704392_+\|terminase	P27 family phage terminase small subunit	A0A0U4JV93	Exiguobacterium_phage	6.2e-32	64.5
WP_025364416.1\|1704388_1706116_+\|terminase	terminase large subunit	A6XMJ4	Bacillus_virus	4.0e-265	73.5
WP_025364417.1\|1706117_1707320_+\|portal	phage portal protein	A6XMJ5	Bacillus_virus	6.2e-172	73.3
WP_025364418.1\|1707312_1707888_+\|head,protease	HK97 family phage prohead protease	Q0H262	Geobacillus_phage	7.5e-75	71.7
WP_025364419.1\|1707887_1709198_+\|capsid	phage major capsid protein	A0A0U4IB53	Exiguobacterium_phage	5.8e-99	59.9
WP_025364420.1\|1709194_1709752_+	hypothetical protein	NA	NA	NA	NA
WP_025364421.1\|1709753_1710029_+	hypothetical protein	Q0H259	Geobacillus_phage	3.0e-29	73.3
WP_025364422.1\|1710025_1710337_+\|head	phage head closure protein	A6XMK0	Bacillus_virus	2.0e-29	64.1
WP_025364423.1\|1710329_1710716_+	HK97 gp10 family phage protein	A6M956	Geobacillus_virus	2.1e-25	65.6
WP_019686676.1\|1710715_1711051_+	hypothetical protein	A6M957	Geobacillus_virus	1.9e-30	61.8
WP_019686677.1\|1711055_1711658_+\|tail	tail protein	A6M958	Geobacillus_virus	1.1e-65	63.9
WP_025364424.1\|1711654_1712038_+	hypothetical protein	A6M959	Geobacillus_virus	1.7e-19	44.4
WP_019686679.1\|1712051_1712219_+	hypothetical protein	NA	NA	NA	NA
WP_025364425.1\|1712236_1716688_+	hypothetical protein	A6M961	Geobacillus_virus	5.7e-29	34.6
WP_025364426.1\|1716684_1717251_+	hypothetical protein	A0A290FZP5	Caldibacillus_phage	2.0e-19	36.0
WP_025364427.1\|1717263_1717674_+	hypothetical protein	H6BJ44	Methylophilales_phage	2.3e-25	41.6
WP_025364428.1\|1717722_1719090_+	hypothetical protein	A0A2H4JE68	uncultured_Caudovirales_phage	1.3e-05	34.0
WP_025364429.1\|1719105_1719738_+	hypothetical protein	NA	NA	NA	NA
WP_025364430.1\|1719748_1721662_+	hypothetical protein	A0A0U4B063	Bacillus_phage	2.6e-132	49.5
WP_025364431.1\|1721655_1722216_-	hypothetical protein	NA	NA	NA	NA
WP_025364432.1\|1722381_1723470_+	hypothetical protein	A0A0A0RNC0	Bacillus_phage	6.3e-06	22.9
WP_025364433.1\|1723589_1724054_+\|holin	phage holin family protein	R9TMD4	Paenibacillus_phage	1.8e-39	61.5

DBSCAN-SWA_4

1903128 : 1912529

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_016819632.1\|1903128_1904049_+	glucose 1-dehydrogenase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	3.4e-53	41.8
WP_016819633.1\|1904169_1905972_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	3.2e-39	36.3
WP_013370356.1\|1906100_1906832_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.5e-37	34.5
WP_025364515.1\|1906989_1908114_+	CBS domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	5.3e-08	26.9
WP_016819635.1\|1908241_1909000_+	phosphate ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.5e-14	32.4
WP_016819636.1\|1909039_1909699_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_025364516.1\|1909874_1912529_+	DNA polymerase I	A0A060AM05	Listeria_phage	2.3e-46	29.8

DBSCAN-SWA_5

3003132 : 3010924

Bacillus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025364968.1\|3003132_3003969_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.1e-18	37.3
WP_025364969.1\|3003961_3004804_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	3.7e-14	24.3
WP_025364970.1\|3004770_3006081_+	MATE family efflux transporter	NA	NA	NA	NA
WP_025364971.1\|3006202_3007660_-	catalase	A0A2K9L0T1	Tupanvirus	7.9e-113	42.8
WP_017427014.1\|3007948_3008551_-	adenylyl-sulfate kinase	NA	NA	NA	NA
WP_025364972.1\|3008600_3009500_-	TIGR02452 family protein	G3MBH6	Bacillus_virus	1.2e-58	46.5
WP_025364973.1\|3009505_3009988_-	NADAR family protein	A0A0S0N9W6	Pseudomonas_phage	4.1e-42	55.5
WP_017427017.1\|3010018_3010924_-	NUDIX hydrolase	G3MA14	Bacillus_virus	2.4e-35	33.8

DBSCAN-SWA_6

3374076 : 3381269

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025365141.1\|3374076_3375339_-	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	3.9e-07	31.9
WP_025365142.1\|3375551_3376274_+	protein-glutamine gamma-glutamyltransferase	NA	NA	NA	NA
WP_016822238.1\|3376364_3376853_-	sporulation protein YtfJ	NA	NA	NA	NA
WP_016822240.1\|3377806_3378415_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.1e-15	33.3
WP_025365143.1\|3378383_3379178_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	3.7e-08	30.5
WP_025366264.1\|3379351_3379816_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	7.4e-41	59.2
WP_038978072.1\|3379845_3380490_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.1e-58	55.7
WP_025365144.1\|3380603_3381269_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	3.8e-38	40.5

DBSCAN-SWA_7

3693392 : 3735194

Paenibacillus_phage(46.88%)

portal,plate,terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025365253.1\|3693392_3694514_-	hypothetical protein	A0A0A0RNC0	Bacillus_phage	3.2e-05	25.0
WP_025365255.1\|3696597_3697125_-	YmfQ family protein	S6BFJ0	Thermus_phage	7.7e-26	40.6
WP_025365256.1\|3697151_3698228_-\|plate	baseplate J/gp47 family protein	A0A2H4J4A0	uncultured_Caudovirales_phage	5.4e-58	40.6
WP_025365257.1\|3698227_3698653_-	DUF2634 domain-containing protein	A0A2H4J6K5	uncultured_Caudovirales_phage	1.7e-20	37.9
WP_025365258.1\|3698642_3699107_-	DUF2577 domain-containing protein	NA	NA	NA	NA
WP_080690765.1\|3700233_3700830_-	LysM peptidoglycan-binding domain-containing protein	A0A2H4J2N2	uncultured_Caudovirales_phage	1.2e-40	44.2
WP_158442529.1\|3700919_3702905_-\|tail	phage tail tape measure protein	A0A1B1P7S6	Bacillus_phage	1.2e-66	48.2
WP_025365262.1\|3703161_3703536_-	hypothetical protein	A0A2H4J7P7	uncultured_Caudovirales_phage	1.5e-15	46.1
WP_025365263.1\|3703595_3704036_-\|tail	phage tail tube protein	A0A0N7ACS0	Bacillus_phage	1.6e-29	44.1
WP_025365264.1\|3704053_3705100_-	hypothetical protein	A0A2H4J187	uncultured_Caudovirales_phage	1.9e-92	51.5
WP_025365265.1\|3705146_3705575_-	hypothetical protein	NA	NA	NA	NA
WP_025365266.1\|3705576_3706050_-	hypothetical protein	NA	NA	NA	NA
WP_025365267.1\|3706050_3706368_-	hypothetical protein	NA	NA	NA	NA
WP_025365268.1\|3706369_3706768_-	hypothetical protein	A0A0N9SGG4	Paenibacillus_phage	2.3e-22	46.0
WP_025365269.1\|3706782_3706992_-	hypothetical protein	NA	NA	NA	NA
WP_025365270.1\|3706991_3707432_-	hypothetical protein	NA	NA	NA	NA
WP_025365271.1\|3707481_3708600_-	DUF5309 family protein	A0A096XUT2	Cronobacter_phage	8.4e-06	25.8
WP_039269106.1\|3708657_3709335_-	hypothetical protein	A0A2H4IZP8	uncultured_Caudovirales_phage	1.6e-20	41.6
WP_025365272.1\|3709408_3710224_-	type IV secretion protein Rhs	A0A0N9SJR1	Paenibacillus_phage	3.8e-64	45.9
WP_039269275.1\|3710223_3711600_-\|portal	portal protein	A0A2H4J180	uncultured_Caudovirales_phage	1.4e-124	51.5
WP_025365274.1\|3711866_3712187_+	hypothetical protein	NA	NA	NA	NA
WP_025365275.1\|3712188_3713625_-\|terminase	phage terminase large subunit	A0A0N9RZA7	Paenibacillus_phage	2.3e-149	56.6
WP_025365276.1\|3714045_3714288_-	hypothetical protein	NA	NA	NA	NA
WP_025365277.1\|3714302_3714509_-	hypothetical protein	A0A0K2CZA1	Paenibacillus_phage	2.0e-22	79.1
WP_025365278.1\|3715119_3715509_-	hypothetical protein	A0A0N7GFF5	Paenibacillus_phage	4.9e-38	66.9
WP_025365279.1\|3716135_3717014_-	hypothetical protein	A0A0N9S810	Paenibacillus_phage	4.9e-09	22.6
WP_151259639.1\|3717010_3717190_-	hypothetical protein	NA	NA	NA	NA
WP_025365280.1\|3717488_3718271_+	FRG domain-containing protein	NA	NA	NA	NA
WP_025365281.1\|3718371_3718578_+	hypothetical protein	NA	NA	NA	NA
WP_158442530.1\|3718832_3718991_-	hypothetical protein	NA	NA	NA	NA
WP_025365282.1\|3718987_3719176_-	hypothetical protein	NA	NA	NA	NA
WP_080690740.1\|3719573_3719774_+	helix-turn-helix transcriptional regulator	A0A2I7SC05	Paenibacillus_phage	8.7e-15	57.8
WP_025365283.1\|3719723_3720284_-	hypothetical protein	A0A0N7GFF4	Paenibacillus_phage	1.9e-35	55.4
WP_025365284.1\|3720316_3720712_-	DUF134 domain-containing protein	A0A0N9RZI0	Paenibacillus_phage	4.5e-31	56.2
WP_151259620.1\|3720834_3721026_-	hypothetical protein	NA	NA	NA	NA
WP_158442531.1\|3720991_3721168_-	hypothetical protein	NA	NA	NA	NA
WP_025365285.1\|3721164_3722724_-	DUF4942 domain-containing protein	A0A0U4JGM1	Vibrio_phage	6.0e-10	31.0
WP_025365286.1\|3722796_3723357_-	hypothetical protein	A0A0N9SJZ0	Paenibacillus_phage	5.6e-43	51.1
WP_025365287.1\|3723353_3723560_-	hypothetical protein	NA	NA	NA	NA
WP_025365288.1\|3723552_3723993_-	hypothetical protein	NA	NA	NA	NA
WP_025365289.1\|3723989_3725072_-	hypothetical protein	A0A0N9RTN7	Paenibacillus_phage	3.0e-16	44.7
WP_151259623.1\|3725251_3725557_+	hypothetical protein	NA	NA	NA	NA
WP_080690741.1\|3725540_3726062_-	hypothetical protein	A0A142F1S8	Bacillus_phage	8.4e-25	58.0
WP_039269109.1\|3725971_3726607_-	hypothetical protein	NA	NA	NA	NA
WP_025365291.1\|3726619_3726877_-	hypothetical protein	NA	NA	NA	NA
WP_025365292.1\|3727061_3727874_-	FAD-dependent thymidylate synthase	A0A142F1S2	Bacillus_phage	1.5e-81	60.8
WP_025365293.1\|3728375_3728939_-	deoxyuridine 5'-triphosphate nucleotidohydrolase	D2XR49	Bacillus_phage	2.8e-34	48.9
WP_025365294.1\|3729097_3729451_-	hypothetical protein	R9TNM9	Paenibacillus_phage	4.3e-25	55.5
WP_025365295.1\|3729450_3730305_-	hypothetical protein	A0A0N9RTN7	Paenibacillus_phage	2.3e-19	30.8
WP_158442532.1\|3730497_3730665_-	hypothetical protein	NA	NA	NA	NA
WP_025365296.1\|3730677_3732939_-	ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent	A7XX33	Thermus_virus	2.2e-117	38.1
WP_025365297.1\|3733110_3733341_-	hypothetical protein	NA	NA	NA	NA
WP_025365298.1\|3733522_3734068_-	hypothetical protein	A0A0N9ST03	Paenibacillus_phage	4.5e-13	55.7
WP_025365299.1\|3734045_3734555_-	hypothetical protein	NA	NA	NA	NA
WP_158442533.1\|3734555_3735194_-	hypothetical protein	A0A0N9SHN6	Paenibacillus_phage	7.5e-68	58.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP006872

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection