CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022898	Bacillus subtilis PY79, complete sequence	3 crisprs	csa3,cas3,DEDDh,WYL,DinG	0	1	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_022898_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022898_1

900979-901084

Orphan

Consensus_repeat	Method
AGAAAACAAAACCAACAATCAGCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022898_1

>merge|NC_022898|1|900979-901084|CRISPRCasFinder
AGAAAACAAAACCAACAATCAGCTGCTGGTCAAGGTCAATTTGGCACTGAATTTGCTAGCGAAACAAACGCTCAGCAAGTCAGAAAACAAAACCAGCAATCAGCTG

>NC_022898|1|1|900979-901084|CRISPRCasFinder
AGAAAACAAAACCAACAATCAGCTG	CTGGTCAAGGTCAATTTGGCACTGAATTTGCTAGCGAAACAAACGCTCAGCAAGTC
AGAAAACAAAACCAGCAATCAGCTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_022898.1\|WP_003223272.1\|901764_902295_+\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|184219
NC_022898.1\|WP_009966836.1\|902382_904125_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_022898.1\|WP_003243789.1\|891422_891692_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379438
NC_022898.1\|WP_003243363.1\|891836_892355_+\|SH3-domain-containing-protein	unknown	unknown	gnl\|CDD\|214600
NC_022898.1\|WP_003243536.1\|907992_908346_-\|YgzB-family-protein	unknown	unknown	gnl\|CDD\|371346
NC_022898.1\|WP_003233542.1\|899806_900031_-\|hypothetical-protein	unknown	unknown	unknown
NC_022898.1\|WP_003233537.1\|904201_905263_-\|aromatic-acid-exporter-family-protein	unknown	unknown	gnl\|CDD\|226614
NC_022898.1\|WP_003243838.1\|898689_899799_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|130156
NC_022898.1\|WP_003244113.1\|893851_894841_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133030
NC_022898.1\|WP_009969309.1\|894912_897498_+\|YfhO-family-protein	unknown	unknown	gnl\|CDD\|226888
NC_022898.1\|WP_003242803.1\|892439_892772_+\|SdpC-immunity-protein-SpdL	unknown	unknown	gnl\|CDD\|227945
NC_022898.1\|WP_003243727.1\|908553_909438_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379641
NC_022898.1\|WP_003233532.1\|906924_907398_+\|thioredoxin-dependent-thiol-peroxidase	unknown	unknown	gnl\|CDD\|224146
NC_022898.1\|WP_003233481.1\|916406_917183_-\|sporulation-control-protein-Spo0M	unknown	unknown	gnl\|CDD\|226776
NC_022898.1\|WP_003223262.1\|900112_900865_+\|enoyl-[acyl-carrier-protein]-reductase-FabL	unknown	unknown	gnl\|CDD\|236145
NC_022898.1\|WP_003223285.1\|907520_907958_+\|peroxide-responsive-transcriptional-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
NC_022898.1\|WP_003243419.1\|892758_893619_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_022898.1\|WP_009968853.1\|901276_901621_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372951
NC_022898.1\|WP_003244136.1\|897490_898474_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899
NC_022898.1\|WP_003233535.1\|905482_906772_-\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|183493

Protein	Function_ID	Function_description	E-value
NC_022898.1\|WP_003223272.1\|901764_902295_+\|DUF402-domain-containing-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	7.36814e-127
NC_022898.1\|WP_009966836.1\|902382_904125_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NC_022898.1\|WP_003243789.1\|891422_891692_+\|hypothetical-protein	gnl\|CDD\|379438	pfam14043, WVELL, WVELL protein. This family includes the B. subtilis YfjH protein, which is functionally uncharacterized. This is not a homolog of E. coli YfjH, a synonym for IscX, which belongs to pfam04384. This family of proteins is found in bacteria. Proteins in this family are approximately 90 amino acids in length and contain a highly conserved WVELL motif.	4.98563e-41
NC_022898.1\|WP_003243363.1\|891836_892355_+\|SH3-domain-containing-protein	gnl\|CDD\|214600	smart00287, SH3b, Bacterial SH3 domain homologues.	2.69836e-13
NC_022898.1\|WP_003243536.1\|907992_908346_-\|YgzB-family-protein	gnl\|CDD\|371346	pfam11023, DUF2614, Zinc-ribbon containing domain. This is a family of proteins conserved in the Bacillaceae family. Some members are annotated as being protein YgzB. The function is not known.	3.8424e-68
NC_022898.1\|WP_003233537.1\|904201_905263_-\|aromatic-acid-exporter-family-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	2.49461e-90
NC_022898.1\|WP_003243838.1\|898689_899799_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|130156	TIGR01084, A/G-specific_adenine_glycosylase, A/G-specific adenine glycosylase. This equivalog model identifies mutY members of the pfam00730 superfamily (HhH-GPD: Helix-hairpin-helix and Gly/Pro rich loop followed by a conserved aspartate). The major members of the superfamily are nth and mutY. [DNA metabolism, DNA replication, recombination, and repair].	5.10517e-157
NC_022898.1\|WP_003244113.1\|893851_894841_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	2.54502e-85
NC_022898.1\|WP_009969309.1\|894912_897498_+\|YfhO-family-protein	gnl\|CDD\|226888	COG4485, COG4485, Predicted membrane protein [Function unknown].	0
NC_022898.1\|WP_003242803.1\|892439_892772_+\|SdpC-immunity-protein-SpdL	gnl\|CDD\|227945	COG5658, COG5658, Predicted integral membrane protein [Function unknown].	1.0168e-26
NC_022898.1\|WP_003243727.1\|908553_909438_+\|hypothetical-protein	gnl\|CDD\|379641	pfam14540, NTF-like, Nucleotidyltransferase-like. Structural comparisons with Structure 1kny indicate that this N-terminal domain resembles a nucleotidyltransferase fold.	1.16999e-58
NC_022898.1\|WP_003233532.1\|906924_907398_+\|thioredoxin-dependent-thiol-peroxidase	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	6.45936e-86
NC_022898.1\|WP_003233481.1\|916406_917183_-\|sporulation-control-protein-Spo0M	gnl\|CDD\|226776	COG4326, Spo0M, Sporulation control protein [General function prediction only].	1.87454e-155
NC_022898.1\|WP_003223262.1\|900112_900865_+\|enoyl-[acyl-carrier-protein]-reductase-FabL	gnl\|CDD\|236145	PRK08063, PRK08063, enoyl-[acyl-carrier-protein] reductase FabL.	2.59874e-172
NC_022898.1\|WP_003223285.1\|907520_907958_+\|peroxide-responsive-transcriptional-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	2.19115e-56
NC_022898.1\|WP_003243419.1\|892758_893619_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.87358e-38
NC_022898.1\|WP_009968853.1\|901276_901621_+\|hypothetical-protein	gnl\|CDD\|372951	pfam14182, YgaB, YgaB-like protein. The YgaB-like protein family includes the B. subtilis YgaB protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 90 amino acids in length.	1.16495e-28
NC_022898.1\|WP_003244136.1\|897490_898474_-\|metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	2.00254e-44
NC_022898.1\|WP_003233535.1\|905482_906772_-\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0

>NC_022898.1|WP_003223262.1|900112_900865_+|enoyl-[acyl-carrier-protein]-reductase-FabL
MEQNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKANVGQPAKIKEMFQQIDETFGRLDVFVNNAASGVLRPVMELEETHWDWTMNINAKALLFCAQEAAKLMEKNGGGHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVSGGAIDTDALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKADMIRGQTIIVDGGRSLLV
>NC_022898.1|WP_003233542.1|899806_900031_-|hypothetical-protein
MYVGRDMSELNMVSKKDWKNSELAYFHHAFQQIMPYLNEEGQSKYRELTQEIEARGGMKRNEADYSHGTRVSYD
>NC_022898.1|WP_003243838.1|898689_899799_+|A/G-specific-adenine-glycosylase
MNVLEDKLKQKDIQQFRDDLISWFEREQRVLPWREDQDPYKVWVSEVMLQQTRVETVIPYFLRFVEQFPTVEALADADEEKVLKAWEGLGYYSRVRNLQSAVKEVKQEYGGIVPPDEKDFGGLKGVGPYTKGAVLSIAYNKPIPAVDGNVMRVMSRILSIWDDIAKPKTRTIFEDAIRAFISKEKPSEFNQGLMELGALICTPKSPSCLLCPVQQHCSAFEEGTERELPVKSKKKKPGIKTMAAIVLTDEDGQVYIHKRPSKGLLANLWEFPNLETQKGIKTEREQLIAFLENEYGIQADISDLQGVVEHVFTHLVWNISVFFGKVKQVSDTSKLKKVTKEELEQFAFPVSHQKIWKMAGEAAAISAAP
>NC_022898.1|WP_003244136.1|897490_898474_-|metal-dependent-hydrolase
MDTGTHVVMGIALGGIATLDPVVGSDPAMAHAVMIATLAGSQAPDIDTVLKLKNNAVYIRNHRGFTHSIPAVLFWSVIIPAILYLFYPQADFLHLWLWTLLAVVLHVFVDIFNAYGTQAIRPFSKKWVALGLINTFDPFIFISHLAAIAIWYAGGSPGITFLSLYIILVGYYLVRLIMQLRIKRKLHEMIHDEIESIIISPTMKFRQWRIAVTTAHAFYVGRSMEGHVVILDTFNRVPVPETDVMHAAKQDDNIAAFLSFSPVYRWEVDTFKDHYEVRFIDLRYRSKGHYPFVAIVHIGHDLTIRSSYTGWIFSEEKLQKKLKLGSI
>NC_022898.1|WP_009969309.1|894912_897498_+|YfhO-family-protein
MKRKHIMIYAASLLVSVLAHAFFVKEWAEGRYMTGPGDGLAQMIVFKKLLFDQYTHGNFFYNYSFGLGGGTFSQLGYYFSASFLFLAVSAAVWLLQAVQLIGETDTLFWAESAVFISIFKLSLIIFTSASVFHYLLKHRAASFTGAVLYGVSIIYFRHEAYWEFFTDTMVWLPLLVLGAEKIIRERRPAWFIVACSLTLINNFYFAYINLIFIGIYVLFRWLIRLEPHEEKRWIQIRLFLVSGFISFGISAAAFVPVVYGFLNNLRPPYSQKIEWLNFDDNILFSSRIIIVPAAFLLFLFIISFYKNRVFRLFAGLSLLFILFHFSPYAASVFNGFSAPQNRFEYVLAFTIAGAAAAGLSQLSELKRKELLPAAAVVLLLYLYHIQRYKLDIWKPANESILLLLLMTIAALFAAAFAKKRAKMAVYGIIILSSLFVANSYQKYALSEGGDLDSVTKEYLTSEEYRGRESSELIRRLQKEDDDPLMRIDWMNGVRNNTPIIYGFNGFSAYSSILNKDLLAFYWNDLSIDMGRESVSRYASLGDRANLYSLLYGKYYMTEKTNEASVPYGFKKHLETEHYAVYENQYMLPFVKTADAIYSESELDRLPALAKEQAMLKGIILKDPSGKTEQTPKPSNLITKSDITAKQAQYQNGLLTVTGENGGELIITPKQPSSAPGDYYVSFYLKSKAKDKGFTLKVNDYVTTRKSNKSIYKIGVNNITVRVPKSGHISINLPKGTYELRNIALYEENYQTLKNAVMQNKTEKADKLNWNKNRLTFSYHLSKDQYIMLPIPYEKGWELKINGKTQKIEKADYAFIGFKAQKGDNHIELTYYPPYFKISAIISLVSLLLAVFYIRRKKPGSI
>NC_022898.1|WP_003244113.1|893851_894841_+|glycosyltransferase-family-2-protein
MKQGLISIIIPSYNEGYNVKLIHESLKKEFKNIHYDYEIFFINDGSVDDTLQQIKDLAATCSRVKYISFSRNFGKEAAILAGFEHVQGEAVIVMDADLQHPTYLLKEFIKGYEEGYDQVIAQRNRKGDSFVRSLLSSMYYKFINKAVEVDLRDGVGDFRLLSRQAVNALLKLSEGNRFSKGLFCWIGFDQKIVFYENVERKNGTSKWSFSSLFNYGMDGVVSFNHKPLRLCFYTGIFILLLSIIYIIATFVKILTNGISVPGYFTIISAVLFLGGVQLLSLGIIGEYIGRIYYETKKRPHYLIKEANIPNKDLPETNELKSMRRLTKMH
>NC_022898.1|WP_003243419.1|892758_893619_+|alpha/beta-hydrolase
MDGVKCQFVNTNGITLHVAAAGREDGPLIVLLHGFPEFWYGWKNQIKPLVDAGYRVIAPDQRGYNLSDKPEGIDSYRIDTLRDDIIGLITQFTDEKAIVIGHDWGGAVAWHLASTRPEYLEKLIAINIPHPHVMKTVTPLYPPQWLKSSYIAYFQLPDIPEASLRENDYDTLDKAIGLSDRPALFTSEDVSRYKEAWKQPGALTAMLNWYRALRKGSLAEKPSYETVPYRMIWGMEDRFLSRKLAKETERHCPNGHLIFVDEASHWINHEKPAIVNQLILEYLKNQ
>NC_022898.1|WP_003242803.1|892439_892772_+|SdpC-immunity-protein-SpdL
MTGLVGGGLMIIAGILIKLFPPKSINSVYGYRTRRSMSDQRLWNEANRYSASLMILSGLVIAGMGLLLGSNLFILQLILLIAACVITFMLTEKRLKIMTHSQGGDRSGRS
>NC_022898.1|WP_003243363.1|891836_892355_+|SH3-domain-containing-protein
MKKKQVMLALTAAAGLGLTALHSAPAAKAAPLHDISVSMPSSDTYIIKAGKLNVRTEPNHEGDILGTVSSEQKVKVDRFVNADWAQIHFKGKKAYISTHFLMKTASQAKTTKQTAFYTPTPENGKAKQLSSGTEVTILGWGFSENGGFDFTWAFVDYGGVKGYIHTKDLQMR
>NC_022898.1|WP_003243789.1|891422_891692_+|hypothetical-protein
MNMYIEKLTNLLLEKNEMISYIQAKTWVELLWSDFEATYAKAGHAYQGEKMTEKIVTQWIENYGGQLHLFQSSRNDVNDYLNQSRGLLH
>NC_022898.1|WP_009968853.1|901276_901621_+|hypothetical-protein
MSQRVCFMEIEMIKGGNVYTFIRLKEEPMTEFEKLVSEQMKTMDKLLDLQSELDRCKQIEAELRHLERDARLRGIQAEIAVKRKHLADIQDMFQKQTEQVIRSYRSSEKPSSFV
>NC_022898.1|WP_003223272.1|901764_902295_+|DUF402-domain-containing-protein
MGYPKEGETIQIHSYKHNGLIHRIWNETTILKSTEMCVIGANDRTMVTESDGRTWITREPAICYFHARQWFNVIGMLREDGVHYYCNISSPFAYDGEAIKYIDYDLDVKVFPDMTYNILDEDEYDDHRKAMNYPKEIDSILRDYLNTLLHWIHQRQGPFAPEFVDMWYERYLRYTK
>NC_022898.1|WP_009966836.1|902382_904125_+|ABC-transporter-ATP-binding-protein
MGVMKRYMQFVKPYKKQIFVTVLIGIVKFSIPLALPLLLKYVVDDIIQGGGTASDKTTSLFTIMAIMFALFLILRPPVEYYRQYFAQWTASKVLYDIRAKLFDHIQKLSLRFYANTRTGEVISRVINDVEQTKDFVITGLMNIWLDMLTILIVISIMLTLDVKLTLISIVLFPLYGISVKYFYGRLRKLTRERSQALAQVQGHLHERIQGMPVIRSFAIEDHEQAQFNEKNGHFLDKAIRHTNWNAKTFAVVNTITDLAPLIVIACAGYFVINGPLTVGTMVAFVGYIDRMYNPVRRLINSSTTLTQSIASMDRVFEFIDEPYELTDKPNAIKADQIRGGVEFQNVSFQYEKDKENILHDVSLKVNRGETVALVGMSGGGKSTLVSLIPRFYDVTSGRLLIDGTDIRDYEARSLRNQVGMVLQDTFLFSETIRENIAIGKPDATLEEIIEAAKAANAHEFIMSFPEGYETRVGERGVKLSGGQKQRISIARVFLKNPPLLILDEATSALDLESEHYIQEAMDKLAKDRTTFVVAHRLSTITHADKIVVMENGTIIEIGTHDELMDYESQYKHLFTIQNLN
>NC_022898.1|WP_003233537.1|904201_905263_-|aromatic-acid-exporter-family-protein
MKLGARIFKTGIAITLALYLASWIGLPAPIFAGIAAIFAIQPSIYRSFLIIIDQVQANIIGAVIATVFGLIFGPSPIMIGLTAVIVITIMLKLKIEHTISIALVTVIAILESAGDDFLMFALIRTSTVILGVLSSFIVNLVFLPPKYETKLIHNTVENTEEIMKWIRLSMRQSTEHSILKEDIEKLKEKMIKLDQTYLLYKEERSYFKKTTYVKSRKLVLFRQAIITANRALDTLKKLHRLENEIYHMPEEFQETLTEELDYLLYWHERILMRFVGKIKPHDDAVEEGIRYKQLLTKSFLKNQQNTDEELIDYNMLNIMASAVEYREQLEHLETLITSFQTYHPKDCEIETEE
>NC_022898.1|WP_003233535.1|905482_906772_-|glutamate-1-semialdehyde-2,1-aminomutase
MHTKSIELHNEALQHIVGGVNSPSRSYKAVGGGSPVAMEKASGAYFWDVDGNKYIDYLAAYGPIITGHAHPHITEAIKKAAENGVLYGTPTKHEVTFAKMLKEAIPAMDKVRFVNSGTEAVMTTIRVARAYTGRTKIIKFAGCYHGHSDLVLVAAGSGPSTLGTPDSAGVPKSIANEVITVPFNDIDSYKAALEKWGSEIAAVLVEPIVGNFGIVEPKEGFLEQVNELTHNAGALVIYDEVITAFRFMYGGAQDLLQVKPDLTALGKIIGGGLPIGAYGGKQEIMEQVAPLGPAYQAGTMAGNPASILSGIACLEVLKEKGVYEKLDHLGAMLEEGILKHAETHGITITVNRLKGALTVYFSDEKVENYEQAERSDGETFSTFFKLMLERGINLAPSKYEAWFITTAHTEQDIKDTLTAVEDAFKHLKN
>NC_022898.1|WP_003233532.1|906924_907398_+|thioredoxin-dependent-thiol-peroxidase
MTIEIGQKAPDLELKGDHGETVKLSDYKGKYIVLYFYPKDMTPGCTTEACDFRDSHESFAELDAVIIGVSPDSQEKHGKFKEKHNLPFLLLVDDEHKLAEAFDVWKLKKNFGKEYMGIERSTFLIDKEGRLIKEWRKVKVKDHVAEALQTLKDMSEK
>NC_022898.1|WP_003223285.1|907520_907958_+|peroxide-responsive-transcriptional-repressor-PerR
MAAHELKEALETLKETGVRITPQRHAILEYLVNSMAHPTADDIYKALEGKFPNMSVATVYNNLRVFRESGLVKELTYGDASSRFDFVTSDHYHAICENCGKIVDFHYPGLDEVEQLAAHVTGFKVSHHRLEIYGVCQECSKKENH
>NC_022898.1|WP_003243536.1|907992_908346_-|YgzB-family-protein
MAKYSSKINKIRTFALSLVFVGFIIMYIGIFFKESVLLSSLFMILGLLSIGLSTVVYFWIGMLSTKAVRVICPGCDKETKVLGVVDMCMHCREPLTLDKGLEGKEFDESYNKKKMSK
>NC_022898.1|WP_003243727.1|908553_909438_+|hypothetical-protein
MENLLRPIYQERASHPNTLAVIMIERRNKTSSLTDNFDAALLVIVKDADEPVFIKHYEFDHQTASLHVVTDSQIQEWILLGTNRRIIDWIVNGRVLFDRNEYVVELIDRLNTFPFAERKLKIGLEYGKLIRRYVEGKAFFEANQFLDAYNAVVHALHHLARIEVIDRGFHPETTVWSQVRQMEPQVYKLYSELIESHESLEKRLELLFLANDFLIHSKAEIGSAHLFEVMKEKDIWQFGELLQHHDLKHFTQDLGVMLDYLTEKGLINVCQIETKGQAVYHRGYSFKKGVDSDS
>NC_022898.1|WP_003233481.1|916406_917183_-|sporulation-control-protein-Spo0M
MSFFKKLAASAGIGAAKVDTILEKDAYFPGEEVQGTVHVKGGKIAQDIRYIDLQLSTRYVIVKDDEEHRKYATIHSFRVTGSFTIQPGEEHQFPFTFTLPLDTPITVGKVEVAVVTDLDIQGGIDKSDHDRIFVEAHPWIENVLEAIENLGFRLNEADCEQAPYFQRRLPFVQEFEFVPTSGYYRQMLDELELIFLLDEDGLEIIFEVDRRARGLRGWLEEMYNDGEQLVRVRFSQSELEDTEELEEVLEEILDQYAE

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Crispr_ID: NC_022898_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022898_2

2990111-2990218

Orphan

Consensus_repeat	Method
TGATGGGAATCGAACCCACGACAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022898_2

>merge|NC_022898|2|2990111-2990218|CRISPRCasFinder
TGATGGGAATCGAACCCACGACATCAGCTTGGAAGGCTGAGGTTTTACCACTAAACTACACCCGCAATTTTTATTTGGGGCGATTGATGGGAATCGAACCCACGAATG

>NC_022898|2|2|2990111-2990218|CRISPRCasFinder
TGATGGGAATCGAACCCACGACAT	CAGCTTGGAAGGCTGAGGTTTTACCACTAAACTACACCCGCAATTTTTATTTGGGGCGAT
TGATGGGAATCGAACCCACGAATG

Protein	Signature genes	Signature genes Name	Protein_function
NC_022898.1\|WP_004399071.1\|2977112_2977544_-\|hypothetical-protein	unknown	unknown	unknown
NC_022898.1\|WP_003229031.1\|2977545_2978601_-\|spore-coat-protein-CotS	unknown	unknown	gnl\|CDD\|131952
NC_022898.1\|WP_003246015.1\|2983972_2985427_-\|glycogen-synthase-GlgA	unknown	unknown	gnl\|CDD\|234809
NC_022898.1\|WP_003228963.1\|2997779_2998301_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224168
NC_022898.1\|WP_004399110.1\|2981589_2983986_-\|glycogen/starch/alpha-glucan-phosphorylase	unknown	unknown	gnl\|CDD\|273967
NC_022898.1\|WP_003229024.1\|2981091_2981559_+\|TspO/MBR-family-protein	unknown	unknown	gnl\|CDD\|226007
NC_022898.1\|WP_004398841.1\|2985423_2986455_-\|glucose-1-phosphate-adenylyltransferase-subunit-GlgD	unknown	unknown	gnl\|CDD\|273966
NC_022898.1\|WP_004398803.1\|2987617_2989501_-\|1,4-alpha-glucan-branching-enzyme	unknown	unknown	gnl\|CDD\|273667
NC_022898.1\|WP_003228966.1\|2997159_2997738_+\|energy-coupled-thiamine-transporter-ThiT	unknown	unknown	gnl\|CDD\|226377
NC_022898.1\|WP_003243227.1\|3001720_3002929_-\|choline-dehydrogenase	unknown	unknown	gnl\|CDD\|341481
NC_022898.1\|WP_003228960.1\|2998318_2999848_-\|flotillin-lipid-rafts-scaffold-protein-FloT	unknown	unknown	gnl\|CDD\|225177
NC_022898.1\|WP_003244320.1\|3004616_3005159_+\|transcriptional-regulator-GbsR	unknown	unknown	gnl\|CDD\|224427
NC_022898.1\|WP_003243556.1\|3005356_3005902_+\|biofilm-surface-layer-protein-BslA	unknown	unknown	gnl\|CDD\|379999
NC_022898.1\|WP_009968049.1\|2986478_2987621_-\|glucose-1-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|179997
NC_022898.1\|WP_003243361.1\|3001054_3001633_-\|MOSC-domain-containing-protein	unknown	unknown	gnl\|CDD\|377051
NC_022898.1\|WP_003242867.1\|3000560_3001049_+\|DinB-family-protein	unknown	unknown	gnl\|CDD\|378981
NC_022898.1\|WP_003229028.1\|2978615_2979749_-\|spore-coat-protein-CotSA	unknown	unknown	gnl\|CDD\|340831
NC_022898.1\|WP_003243430.1\|3002945_3004418_-\|betaine-aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143437
NC_022898.1\|WP_010886600.1\|2979938_2981012_+\|spore-coat-kinase-CotI	unknown	unknown	gnl\|CDD\|131952
NC_022898.1\|WP_003243808.1\|2999868_3000393_-\|membrane-protein	unknown	unknown	gnl\|CDD\|376684

Protein	Function_ID	Function_description	E-value
NC_022898.1\|WP_003229031.1\|2977545_2978601_-\|spore-coat-protein-CotS	gnl\|CDD\|131952	TIGR02906, Spore_coat_protein_S, spore coat protein, CotS family. Members of this family include the spore coat proteins CotS and YtaA from Bacillus subtilis and, from other endospore-forming bacteria, homologs that are more closely related to these two than to the spore coat proteins YutH and YsxE. The CotS family is more broadly distributed than YutH or YsxE, but still is not universal among spore-formers. [Cellular processes, Sporulation and germination].	3.56293e-130
NC_022898.1\|WP_003246015.1\|2983972_2985427_-\|glycogen-synthase-GlgA	gnl\|CDD\|234809	PRK00654, glgA, glycogen synthase GlgA.	0
NC_022898.1\|WP_003228963.1\|2997779_2998301_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224168	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane].	4.15425e-10
NC_022898.1\|WP_004399110.1\|2981589_2983986_-\|glycogen/starch/alpha-glucan-phosphorylase	gnl\|CDD\|273967	TIGR02093, Glycogen_phosphorylase, glycogen/starch/alpha-glucan phosphorylases. This family consists of phosphorylases. Members use phosphate to break alpha 1,4 linkages between pairs of glucose residues at the end of long glucose polymers, releasing alpha-D-glucose 1-phosphate. The nomenclature convention is to preface the name according to the natural substrate, as in glycogen phosphorylase, starch phosphorylase, maltodextrin phosphorylase, etc. Name differences among these substrates reflect differences in patterns of branching with alpha 1,6 linkages. Members include allosterically regulated and unregulated forms. A related family, TIGR02094, contains examples known to act well on particularly small alpha 1,4 glucans, as may be found after import from exogenous sources. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NC_022898.1\|WP_003229024.1\|2981091_2981559_+\|TspO/MBR-family-protein	gnl\|CDD\|226007	COG3476, COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) [Signal transduction mechanisms].	1.0961e-40
NC_022898.1\|WP_004398841.1\|2985423_2986455_-\|glucose-1-phosphate-adenylyltransferase-subunit-GlgD	gnl\|CDD\|273966	TIGR02092, Glycogen_biosynthesis_protein_GlgD, glucose-1-phosphate adenylyltransferase, GlgD subunit. This family is GlgD, an apparent regulatory protein that appears in an alpha2/beta2 heterotetramer with GlgC (glucose-1-phosphate adenylyltransferase, TIGR02091) in a subset of bacteria that use GlgC for glycogen biosynthesis. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NC_022898.1\|WP_004398803.1\|2987617_2989501_-\|1,4-alpha-glucan-branching-enzyme	gnl\|CDD\|273667	TIGR01515, branching_enzym, alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase. This model describes the glycogen branching enzymes which are responsible for the transfer of chains of approx. 7 alpha(1--4)-linked glucosyl residues to other similar chains (in new alpha(1--6) linkages) in the biosynthesis of glycogen. This enzyme is a member of the broader amylase family of starch hydrolases which fold as (beta/alpha)8 barrels, the so-called TIM-barrel structure. All of the sequences comprising the seed of this model have been experimentally characterized. This model encompasses both bacterial and eukaryotic species. No archaea have this enzyme, although Aquifex aolicus does. Two species, Bacillus thuringiensis and Clostridium perfringens have two sequences each which are annotated as amylases. These annotations are aparrently in error. GP\|18143720 from C. perfringens, for instance, contains the note "674 aa, similar to gp:A14658_1 amylase (1,4-alpha-glucan branching enzyme (EC 2.4.1.18) ) from Bacillus thuringiensis (648 aa); 51.1% identity in 632 aa overlap." A branching enzyme from Porphyromonas gingivales, OMNI\|PG1793, appears to be more closely related to the eukaryotic species (across a deep phylogenetic split) and may represent an instance of lateral transfer from this species' host. A sequence from Arabidopsis thaliana, GP\|9294564, scores just above trusted, but appears either to contain corrupt sequence or, more likely, to be a pseudogene as some of the conserved catalytic residues common to the alpha amylase family are not conserved here. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NC_022898.1\|WP_003228966.1\|2997159_2997738_+\|energy-coupled-thiamine-transporter-ThiT	gnl\|CDD\|226377	COG3859, COG3859, Predicted membrane protein [Function unknown].	1.328e-72
NC_022898.1\|WP_003243227.1\|3001720_3002929_-\|choline-dehydrogenase	gnl\|CDD\|341481	cd08551, Fe-ADH, iron-containing alcohol dehydrogenases (Fe-ADH)-like. This family contains large metal-containing alcohol dehydrogenases (ADH), known as iron-containing alcohol dehydrogenases. They contain a dehydroquinate synthase-like protein structural fold and mostly contain iron. They are distinct from other alcohol dehydrogenases which contains different protein domains. There are several distinct families of alcohol dehydrogenases: Zinc-containing long-chain alcohol dehydrogenases, insect-type, or short-chain alcohol dehydrogenases, iron-containing alcohol dehydrogenases, among others. The iron-containing family has a Rossmann fold-like topology that resembles the fold of the zinc-dependent alcohol dehydrogenases, but lacks sequence homology, and differs in strand arrangement. ADH catalyzes the reversible oxidation of alcohol to acetaldehyde with the simultaneous reduction of NAD(P)+ to NAD(P)H.	1.69004e-175
NC_022898.1\|WP_003228960.1\|2998318_2999848_-\|flotillin-lipid-rafts-scaffold-protein-FloT	gnl\|CDD\|225177	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown].	6.12922e-123
NC_022898.1\|WP_003244320.1\|3004616_3005159_+\|transcriptional-regulator-GbsR	gnl\|CDD\|224427	COG1510, COG1510, Predicted transcriptional regulators [Transcription].	4.43641e-73
NC_022898.1\|WP_003243556.1\|3005356_3005902_+\|biofilm-surface-layer-protein-BslA	gnl\|CDD\|379999	pfam17735, BslA, Biofilm surface layer A. This family includes members such as BslA (previously called YuaB). Secreted BslA from Bacillus subtillis has been shown to form surface layers around the biofilm self-assembling at interfaces of B. subtilis biofilms, forming an elastic film. structural analysis revealed that BslA consists of an Ig-type fold with the addition of an unusual, extremely hydrophobic cap region. The hydrophobic cap exhibits physiochemical properties similar to the hydrophobic surface found in fungal hydrophobins; thus, BslA is defined as member of a class of bacterially produced hydrophobins.	5.35887e-46
NC_022898.1\|WP_009968049.1\|2986478_2987621_-\|glucose-1-phosphate-adenylyltransferase	gnl\|CDD\|179997	PRK05293, glgC, glucose-1-phosphate adenylyltransferase; Provisional.	0
NC_022898.1\|WP_003243361.1\|3001054_3001633_-\|MOSC-domain-containing-protein	gnl\|CDD\|377051	pfam03473, MOSC, MOSC domain. The MOSC (MOCO sulfurase C-terminal) domain is a superfamily of beta-strand-rich domains identified in the molybdenum cofactor sulfurase and several other proteins from both prokaryotes and eukaryotes. These MOSC domains contain an absolutely conserved cysteine and occur either as stand-alone forms or fused to other domains such as NifS-like catalytic domain in Molybdenum cofactor sulfurase. The MOSC domain is predicted to be a sulfur-carrier domain that receives sulfur abstracted by the pyridoxal phosphate-dependent NifS-like enzymes, on its conserved cysteine, and delivers it for the formation of diverse sulfur-metal clusters.	1.34032e-05
NC_022898.1\|WP_003242867.1\|3000560_3001049_+\|DinB-family-protein	gnl\|CDD\|378981	pfam12867, DinB_2, DinB superfamily. The DinB family are an uncharacterized family of potential enzymes. The structure of these proteins is composed of a four helix bundle.	3.20062e-17
NC_022898.1\|WP_003229028.1\|2978615_2979749_-\|spore-coat-protein-CotSA	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.47076e-74
NC_022898.1\|WP_003243430.1\|3002945_3004418_-\|betaine-aldehyde-dehydrogenase	gnl\|CDD\|143437	cd07119, ALDH_BADH-GbsA, Bacillus subtilis NAD+-dependent betaine aldehyde dehydrogenase-like. Included in this CD is the NAD+-dependent, betaine aldehyde dehydrogenase (BADH, GbsA, EC=1.2.1.8) of Bacillus subtilis involved in the synthesis of the osmoprotectant glycine betaine from choline or glycine betaine aldehyde.	0
NC_022898.1\|WP_010886600.1\|2979938_2981012_+\|spore-coat-kinase-CotI	gnl\|CDD\|131952	TIGR02906, Spore_coat_protein_S, spore coat protein, CotS family. Members of this family include the spore coat proteins CotS and YtaA from Bacillus subtilis and, from other endospore-forming bacteria, homologs that are more closely related to these two than to the spore coat proteins YutH and YsxE. The CotS family is more broadly distributed than YutH or YsxE, but still is not universal among spore-formers. [Cellular processes, Sporulation and germination].	1.3698e-134
NC_022898.1\|WP_003243808.1\|2999868_3000393_-\|membrane-protein	gnl\|CDD\|376684	pfam01957, NfeD, NfeD-like C-terminal, partner-binding. NfeD-like proteins are widely distributed throughout prokaryotes and are frequently associated with genes encoding stomatin-like proteins (slipins). There appear to be three major groups: an ancestral group with only an N-terminal serine protease domain and this C-terminal beta sheet-rich domain which is structurally very similar to the OB-fold domain, associated with its neighboring slipin cluster; a second major group with an additional middle, membrane-spanning domain, associated in some species with eoslipin and in others with yqfA; a final 'artificial' group which unites truncated forms lacking the protease region and associated with their ancestral gene partner, either yqfA or eoslipin. This NefD, C-terminal, domain appears to be the major one for relating to the associated protein. NfeD homologs are clearly reliant on their conserved gene neighbor which is assumed to be necessary for function, either through direct physical interaction or by functioning in the same pathway, possibly involve with lipid-rafts.	0.00016613

>NC_022898.1|WP_004398803.1|2987617_2989501_-|1,4-alpha-glucan-branching-enzyme
MAAASPTAHDVYLFHEGSLFKSYQLFGSHYRELNGKSGYEFCVWAPHASEVRVAGDFNSWSGEEHVMHRVNDNGIWTLFIPGIGEKERYKYEIVTNNGEIRLKADPYAIYSEVRPNTASLTYDLEGYSWQDQKWQKKQKAKTLYEKPVFIYELHLGSWKKHSDGRHYSYKELSQTLIPYIKKHGFTHIELLPVYEHPYDRSWGYQGTGYYSPTSRFGPPHDLMKFVDECHQQNIGVILDWVPGHFCKDAHGLYMFDGEPLYEYKEERDRENWLWGTANFDLGKPEVHSFLISNALYWAEFYHIDGFRVDAVANILYWPNQDERHTNPYAVDFLKKLNQTMREAYPHVMMIAEDSTEWPQVTGAVEEGGLGFHYKWNMGWMNDVLKYMETPPEERRHCHQLISFSLLYAFSEHFVLPFSHDEVVYGKKSLLNKMPGDYWQKFAQYRLLLGYMTVHPGKKLIFMGSEFAQFDEWKDTEQLDWFLDSFPMHQKASVFTQDLLRFYQKSKILYEHDHRAQSFEWIDVHNDEQSIFSFIRYGQKHGEALVIICNFTPVVYHQYDVGVPFFTQYIEVLNSDSETYGGSGQINKKPLSAKKGALHHKPCYITMTIPPYGISILRAVKKRGEIKR
>NC_022898.1|WP_009968049.1|2986478_2987621_-|glucose-1-phosphate-adenylyltransferase
MKKQCVAMLLAGGKGSRLSGLTKNMAKPAVSFGGKYRIIDFTLSNCSNSGIDTVGILTQYQPLELNSYIGIGSAWDLDRYNGGVTVLPPYAESSEVKWYKGTASSIYENLNYLNQYDPEYVLILSGDHIYKMDYGKMLDYHIEKKADVTISVIEVGWEEASRFGIMKANPDGTITHFDEKPKFPKSNLASMGIYIFNWPLLKQYLEMDDQNPYSSHDFGKDIIPLLLEEKKKLSAYPFKGYWKDVGTVQSLWEANMDLLKEDSELKLFERKWKIYSVNPNQPPQFISSDAQVQDSLVNEGCVVYGNVSHSVLFQGVTVGKHTTVTSSVIMPDVTIGEHVVIENAIVPNGMVLPDGAVIRSEKDIEEVLLVSEEFVEKELI
>NC_022898.1|WP_004398841.1|2985423_2986455_-|glucose-1-phosphate-adenylyltransferase-subunit-GlgD
MFNNQMLGVIDETTYKHSLQDLTAQRSLGAIPFAGRYRLIDFMLSNMVNADIRSVAIFPKYRYRSLMDHLGAGKEWDLHRKKDGLFFFPSPHLHHEYDEFGSFRQFSDHLDYFHRSTQQYAVISNSHTVCNIQFQYVLKRHQEVGCDVTEVFQDGQSLQIYIMSTTLLKDLIYGHSEKGYKTIQEAVEKESSALTICPYEYSGYAAVIDSVEKYYTHSMELIQPRFWQQVFLPQQPIYTKVKDEPPTKYGKHSTVKNSLVANGCVLEGEVENCILFRAVHVGKGTKLKNCIIMQKTQIGEDCLLEQVISDKDVKIGKATEAAGTAEQPLVLRKGLVQGELMNS
>NC_022898.1|WP_003246015.1|2983972_2985427_-|glycogen-synthase-GlgA
MKILFAVSECTPFVKSGGLADVAGALPKALARLGNEVAVMLPKYSQIPEPWKKRMKKQAECTVAVGWRQQYCGIEHMAENDVNYYFIDNEYYFNRDSLYGHYDDGERFAFFSRAVLEAAKVVNVQADIVHTHDWHTAMVNYLLKEEYRKHPFYERMKSVLTIHNLQFQGIFPPDVTHDLLGLEMDHFHYERLECNGFVNFMKAGIIAADHVTTVSPTYRNEIMTPYYGEQLEQVLQYREDDVTGILNGIDDTFYQPKSDPYIEAQYDSGDLACKLENKTKLQQRMGLPEKNDIPLISMVTRLTKQKGLDLVRRIMHELLEEQDIQLVVLGTGEREFEDYFRYAEFAFHEKCRAYIGFDEPLAHQIYAGSDMFLMPSKFEPCGLGQLIALQYGAIPIVRETGGLYDTVRAYQEEEGTGNGFTFSAFNAHDLKFTIERALSFYCQQDVWKSIVKTAMNADYSWGKSAKEYQRIFEQVTRSGRDVLE
>NC_022898.1|WP_004399110.1|2981589_2983986_-|glycogen/starch/alpha-glucan-phosphorylase
MFSSKERFADLFLKRLEMTCGKSFKDSAKLDQYKTLGNMVREYISADWIETNEKSRSNSGKQTYYLSIEFLLGQLLEQNLMNLGVRDVVEAGLKEIGINLEEILQIENDAGLGNGGLGRLAACFLDSLASLNLPGHGMGIRYKHGLFEQKIVDGHQVELPEQWLKNGNVWEVRNADQAVDVPFWGEVHMTEKSGRLHFRHEQATIVTAVPYDIPIIGYETGTVNTLRLWNAEPYAHYHGGNILSYKRETEAVSEFLYPDDTHDEGKILRLKQQYFLVCASLKSIVNNYRKTHKSLSGLHKKVSIHINDTHPALAVPELMRILLDEENMSWEEAWHITVHTISYTNHTTLSEALEKWPIHLFKPLLPRMYMIIEEINERFCRAVWEKYPGDWKRIENMAITAHGVVKMAHLAIVGSYSVNGVAKIHSDILKEREMRDFHLLFPNRFNNKTNGIAHRRWLLKANPGLSAIITEAIGDEWVKQPESLIRLEPYATDPAFIEQFQNNKSKKKQELADLIFCTAGVVVNPESIFDVQVKRLHAYKRQLLNVLHIMYLYNRLKEDSGFSIYPQTFIFGAKASPSYYYAKKIIKLIHSVAEKVNYDPAVKQLIKVVFLENYRVSMAERIFPASDVSEQISTASKEASGTGNMKFMMNGALTIGTHDGANIEILERVGPDCIYTFGLKADEVLSYQENGGYRSREYYQHDRRIRQVADQLINGFFEGEADEFESIFDSLLPHNDEYFVLKDFSSYADAQERIQADYRERRKWSEHSIVNIAHSGYFSSDRTIREYAKDIWGIKPMM
>NC_022898.1|WP_003229024.1|2981091_2981559_+|TspO/MBR-family-protein
MKKIVGALAVFVITYALFSAAGYLFPVDQEWYNSLKKPDWTPSGTAIGIIWAILFALISLSAAIVYAAFSFKGAKSFWFTLLINYVLNQAFSYFQFTQKNLLAASLDCLLVAITAIVLLIIAKKYSRAASYLLLPYFLWSAFATFLSFTINSMNL
>NC_022898.1|WP_010886600.1|2979938_2981012_+|spore-coat-kinase-CotI
MCPLMAENHEVIEEGNSSELPLSAEDAKKLTELAENVLQGWDVQAEKIDVIQGNQMALVWKVHTDSGAVCLKRIHRPEKKALFSIFAQDYLAKKGMNVPGILPNKKGSLYSKHGSFLFVVYDWIEGRPFELTVKQDLEFIMKGLADFHTASVGYQPPNGVPIFTKLGRWPNHYTKRCKQMETWKLMAEAEKEDPFSQLYLQEIDGFIEDGLRIKDRLLQSTYVPWTEQLKKSPNLCHQDYGTGNTLLGENEQIWVIDLDTVSFDLPIRDLRKMIIPLLDTTGVWDDETFNVMLNAYESRAPLTEEQKQVMFIDMLFPYELYDVIREKYVRKSALPKEELESAFEYERIKANALRQLI
>NC_022898.1|WP_003229028.1|2978615_2979749_-|spore-coat-protein-CotSA
MKIALIATEKLPVPSVRGGAIQIYLEAVAPLIAKKHEVTVFSIKDPNLADREKVDGVHYVHLDEDRYEEAVGAELKKSRFDLVHVCNRPSWVPKLKKQAPDAVFILSVHNEMFAYDKISQAEGEICIDSVAQIVTVSDYIGQTITSRFPSARSKTKTVYSGVDLKTYHPRWTNEGQRAREEMRSELGLHGKKIVLFVGRLSKVKGPHILLQALPDIIEEHPDVMMVFIGSKWFGDNELNNYVKHLHTLGAMQKDHVTFIQFVKPKDIPRLYTMSDVFVCSSQWQEPLARVHYEAMAAGLPIITSNRGGNPEVIEEGKNGYIIHDFENPKQYAERINDLLSSSEKRERLGKYSRREAESNFGWQRVAENLLSVYEKNR
>NC_022898.1|WP_003229031.1|2977545_2978601_-|spore-coat-protein-CotS
MYQKEHEEQIVSEILSYYPFHIDHVALKSNKSGRKIWEVETDHGPKLLKEAQMKPERMLFITQAHAHLQEKGLPIAPIHQTKNGGSCLGTDQVSYSLYDKVTGKEMIYYDAEQMKKVMSFAGHFHHASKGYVCTDESKKRSRLGKWHKLYRWKLQELEGNMQIAASYPDDVFSQTFLKHADKMLARGKEALRALDDSEYETWTKETLEHGGFCFQDFTLARLTEIEGEPFLKELHSITYDLPSRDLRILLNKVMVKLSVWDTDFMVALLAAYDAVYPLTEKQYEVLWIDLAFPHLFCAIGHKYYLKQKKTWSDEKYNWALQNMISVEESKDSFLDKLPELYKKIKAYREAN
>NC_022898.1|WP_004399071.1|2977112_2977544_-|hypothetical-protein
MRSSRQKASISKLDLDQFVFTPPGPMGWQAHDSISAEKEEEEKHLDVGSIRELPHINAPKEYQKETKEKETDRKIVDDEEETKFETTLEPEEERDSKRSAPPYEEEDEDEEPDLAEEAKVEIIILPSESKPAPWFSQTVKRKA
>NC_022898.1|WP_003228966.1|2997159_2997738_+|energy-coupled-thiamine-transporter-ThiT
MNQSKQLVRLIEIAIMTAAAVILDIVSGMFLSMPQGGSVSIMMIPIFLISFRWGVKAGLTTGLLTGLVQIAIGNLFAQHPVQLLLDYIVAFAAIGISGCFASSVRKAAVSKTKGKLIVSVVSAVFIGSLLRYAAHVISGAVFFGSFAPKGTPVWIYSLTYNATYMVPSFIICAIVLCLLFMTAPRLLKSDKA
>NC_022898.1|WP_003228963.1|2997779_2998301_-|GNAT-family-N-acetyltransferase
MVTVREAKLEDIKDIAKVHVDSWRTTYHEIIPIDYLNSLNYKEFEDKWKSRSLKGVFVAQDEKGSVFGFASFGPIRSEQEGYDGELYAIYLLEERQRQGAGRALLAKGAEFLLQHGFSSMFVWVIEQNPSIIFYQAYSPERVAEDNFEIAGVRLKEVGLGWPDLSALKTLLNR
>NC_022898.1|WP_003228960.1|2998318_2999848_-|flotillin-lipid-rafts-scaffold-protein-FloT
MTMPIIMIIGVVFFLLIALIAVFITKYRTAGPDEALIVTGSYLGNKNVHVDEGGNRIKIVRGGGTFVLPVFQQAEPLSLLSSKLDVSTPEVYTEQGVPVMADGTAIIKIGGSIGEIATAAEQFLGKSKDDREQEAREVLEGHLRSILGSMTVEEIYKNREKFSQEVQRVASQDLAKMGLVIVSFTIKDVRDKNGYLESLGKPRIAQVKRDADIATAEADKETRIKRAEADKDAKKSELERATEIAEAEKINQLKMAEFRREQDTAKANADQAYDLETARARQQVTEQEMQVKIIERQKQIELEEKEILRRERQYDSEVKKKADADRYSVEQSAAAEKAKQLAEADAKKYSIEAMAKAEAEKVRIDGLAKAEAEKAKGETEAEVIRLKGLAEAEAKEKIAAAFEQYGQAAIFDMIVKMLPEYAKQAAAPLSNIDKITVVDTGGSGESSGANKVTSYATNLMSSLQESLKASSGIDVKEMLENFSGKGNVKQSINELTNEIKEAKTIQKSE
>NC_022898.1|WP_003243808.1|2999868_3000393_-|membrane-protein
MELFGVPIQTMYLYTLIIAGSLTLLFLFFGDVFSGLSEGIPFLNPTLVLSFFTCFSAGGYIGELVLPLSSLLIALLSCILSIMLVVLLHIFVLVPLSSAEESLAYREDDLRGRLGKVITAVPVDGFGEVVIEGIGGTISKSAVSFDNQQISYGTTVLVVDINNGVLSVTPHEPI
>NC_022898.1|WP_003242867.1|3000560_3001049_+|DinB-family-protein
MSIFNEARLETWNELKGLSDEKLNQKPSAEEWSIREVLDHLKKIDMTAQKMLKERVKDAPIKEIEEKPLEVAQDRNNKRKAPSHLEPAHDFISGSQMKRELDVVREQLTAAIASLKEEDFERVLPHPVFQELTVRQWIDFIGHHEKRHLSQMKEIKEKIERA
>NC_022898.1|WP_003243361.1|3001054_3001633_-|MOSC-domain-containing-protein
MWKRMTAKAEGLYIADTKSFVTKQMDKLDFDYGGIPGDLHFGLTKKAGAREPMFSRGTEIFNRRQISIVSIEECNEIALKMGVPRILPEWLGANVAVSGMPDLTSLKEGSRIIFPSGAALLCEGENDPCIQPGEVIQSYYPDQPKLASAFVRHALGIRGIVCIVERPGAVYTGDEIEVHSYQRKVKRKAERV
>NC_022898.1|WP_003243227.1|3001720_3002929_-|choline-dehydrogenase
MTLNMKVESMQKFHTFEIPTVIKHGIGAIKHTGEEVAALGVSKALLVTDPGIYKAGVADPVIESLKEAGIEVVLFNKVEPNPPVRLVNEGSELYKKENCNGLVAVGGGSSMDTAKAIGVEATHEGSVLDYEAADGKKPLENRIPPLTTIPTTAGTGSEVTQWAVITDEEREFKFNTGGPLIAAHLTIIDPELHVSMPPHVTAMTGIDALAHAIECYTMKFAQPITDAVALMAIEYAAHYIKRAFADGEDLEARYGMAQAAMLAGLSYGSESAGAAHAMSQTLGGIIPVAHGQCVAAMMGPVMEYNWKGYPEKFARIAKAFGIDTSKMTTEEAAKASVNWMYDLVEDLEVPTLEEQGVSPDMIERLSKEAMKDPQTFGNPRDLNEKAYNWIYKRCFNLTPKTV
>NC_022898.1|WP_003243430.1|3002945_3004418_-|betaine-aldehyde-dehydrogenase
MSQTLFIDGEWISAEKEQIRSIINPFNQEEIATVSEGGREDAIKAIAAARRAFDKGEWSSLSGLERGKIVLKIAELIRRDLEELAELESLDTGKTLEESKADMDDIANVFQYYAGLADKDGGEIISSPIPDSESKIIREPIGVCGQITPWNYPLLQASWKIAPALAAGNTIVMKPSEITPLTTIKVFKLMEEAGVPKGVANLVLGPGATVGDELAVNKDVDLISFTGGIETGKKIMRAASGNVKKIALELGGKNPNIVFKDADLEVAVDQALNAVFFHAGQVCSAGSRLLVEDAIHDQFLAELVKRAKRIKLGNGFHAETESGPLISAEHRAKVEKYVEIGIEEGAKLETGGKRPEDPELQNGFFYEPTIFSNCNSDMRIVQEEVFGPVLTVETFSSEEEVIELANDTIYGLAGAVWSKDIEKCERVAARLRMGTVWINDFHPYFAQAPWGGYKQSGFGRELGKIGLEEYTEVKHVYRNTKPAAVNWFNS
>NC_022898.1|WP_003244320.1|3004616_3005159_+|transcriptional-regulator-GbsR
MDENPEFAAIEQARDLVIDSIAETMDLYGITRSVGILYGTMYMRDEMTLDEMREELQMSKPSMSTGVKKLQDLNVVKKTFHRGIRKHTFVAEKDFFKFFTNFFPPKWEREVQVNVTAIEEAQADLQKVLCKEDLDEDIKNEALQLYDQLESSKAYYDWLKRLAESVQTGEIFKFIPVETK
>NC_022898.1|WP_003243556.1|3005356_3005902_+|biofilm-surface-layer-protein-BslA
MKRKLLSSLAISALSLGLLVSAPTASFAAESTSTKAHTESTMRTQSTASLFATITGASKTEWSFSDIELTYRPNTLLSLGVMEFTLPSGFTANTKDTLNGNALRTTQILNNGKTVRVPLALDLLGAGEFKLKLNNKTLPAAGTYTFRAENKSLSIGNKFYAEASIDVAKRSTPPTQPCGCN

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Click the colored protein region to show detailed information

Crispr_ID: NC_022898_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022898_3

3532846-3532958

Orphan

Consensus_repeat	Method
GAAGATTTTAGTGATCGTTTAGATGATTTTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022898_3

>merge|NC_022898|3|3532846-3532958|CRISPRCasFinder
GAAGATTTTAGTGATCGTTTAGATGATTTTGAAGAACTTTTTGAACGTGACGAACGACCAGATTTGGATGATTGATCATCTGAAGATTTTAGTGATCGTTTAGATGATTTTGA

>NC_022898|3|3|3532846-3532958|CRISPRCasFinder
GAAGATTTTAGTGATCGTTTAGATGATTTTGA	AGAACTTTTTGAACGTGACGAACGACCAGATTTGGATGATTGATCATCT
GAAGATTTTAGTGATCGTTTAGATGATTTTGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_022898.1\|WP_003242788.1\|3526025_3526553_-\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|225158
NC_022898.1\|WP_003243460.1\|3525689_3525986_+\|DUF3892-domain-containing-protein	unknown	unknown	gnl\|CDD\|379026
NC_022898.1\|WP_003244057.1\|3527481_3529194_-\|acetolactate-synthase-AlsS	unknown	unknown	gnl\|CDD\|236312
NC_022898.1\|WP_010886627.1\|3535091_3535679_+\|spore-coat-protein-CotG	unknown	unknown	unknown
NC_022898.1\|WP_003227852.1\|3535852_3536470_+\|flavin-reductase-family-protein	unknown	unknown	gnl\|CDD\|224766
NC_022898.1\|WP_003242945.1\|3540639_3541185_-\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NC_022898.1\|WP_003227854.1\|3533862_3534951_-\|spore-coat-protein-CotH	unknown	unknown	gnl\|CDD\|227642
NC_022898.1\|WP_003242695.1\|3531855_3532533_-\|DUF2642-domain-containing-protein	unknown	unknown	unknown
NC_022898.1\|WP_003227840.1\|3539858_3540395_+\|chromate-resistance-efflux-protein-ChrA	unknown	unknown	gnl\|CDD\|224970
NC_022898.1\|WP_003227843.1\|3539268_3539862_+\|chromate-efflux-transporter-subunit-ChrB	unknown	unknown	gnl\|CDD\|224970
NC_022898.1\|WP_003227850.1\|3536647_3536983_+\|DUF4181-domain-containing-protein	unknown	unknown	gnl\|CDD\|372726
NC_022898.1\|WP_003244457.1\|3526652_3527420_-\|acetolactate-decarboxylase	unknown	unknown	gnl\|CDD\|273524
NC_022898.1\|WP_003243378.1\|3540421_3540643_-\|hypothetical-protein	unknown	unknown	unknown
NC_022898.1\|WP_003227859.1\|3529351_3530260_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176143
NC_022898.1\|WP_003242900.1\|3538778_3539255_+\|chromate-efflux-transcriptional-regulator-ChrS	unknown	unknown	gnl\|CDD\|214628
NC_022898.1\|WP_009968282.1\|3523018_3523987_+\|ribose-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|181922
NC_022898.1\|WP_003242760.1\|3523998_3524916_+\|ribose-ABC-transporter-substrate-binding-protein-RbsB	unknown	unknown	gnl\|CDD\|380546
NC_022898.1\|WP_003243596.1\|3524997_3525534_+\|SH3-domain-containing-protein	unknown	unknown	gnl\|CDD\|214600
NC_022898.1\|WP_003227847.1\|3536987_3538565_-\|gamma-glutamyltransferase	unknown	unknown	gnl\|CDD\|129176
NC_022898.1\|WP_010886626.1\|3530470_3531799_+\|arsenic-transporter	unknown	unknown	gnl\|CDD\|238538

Protein	Function_ID	Function_description	E-value
NC_022898.1\|WP_003242788.1\|3526025_3526553_-\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|225158	COG2249, MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only].	1.33013e-57
NC_022898.1\|WP_003243460.1\|3525689_3525986_+\|DUF3892-domain-containing-protein	gnl\|CDD\|379026	pfam13031, DUF3892, Protein of unknown function (DUF3892). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 87 and 104 amino acids in length.	4.59339e-16
NC_022898.1\|WP_003244057.1\|3527481_3529194_-\|acetolactate-synthase-AlsS	gnl\|CDD\|236312	PRK08617, PRK08617, acetolactate synthase AlsS.	0
NC_022898.1\|WP_003227854.1\|3533862_3534951_-\|spore-coat-protein-CotH	gnl\|CDD\|227642	COG5337, CotH, Spore coat assembly protein [Cell envelope biogenesis, outer membrane].	0
NC_022898.1\|WP_003242945.1\|3540639_3541185_-\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	6.41336e-37
NC_022898.1\|WP_003227852.1\|3535852_3536470_+\|flavin-reductase-family-protein	gnl\|CDD\|224766	COG1853, COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only].	2.41792e-45
NC_022898.1\|WP_003227850.1\|3536647_3536983_+\|DUF4181-domain-containing-protein	gnl\|CDD\|372726	pfam13789, DUF4181, Domain of unknown function (DUF4181).	0.000225734
NC_022898.1\|WP_003227840.1\|3539858_3540395_+\|chromate-resistance-efflux-protein-ChrA	gnl\|CDD\|224970	COG2059, ChrA, Chromate transport protein ChrA [Inorganic ion transport and metabolism].	7.8803e-49
NC_022898.1\|WP_003227843.1\|3539268_3539862_+\|chromate-efflux-transporter-subunit-ChrB	gnl\|CDD\|224970	COG2059, ChrA, Chromate transport protein ChrA [Inorganic ion transport and metabolism].	1.86288e-53
NC_022898.1\|WP_003244457.1\|3526652_3527420_-\|acetolactate-decarboxylase	gnl\|CDD\|273524	TIGR01252, Alpha-acetolactate_decarboxylase, alpha-acetolactate decarboxylase. Puruvate can be fermented to 2,3-butanediol. It is first converted to alpha-acetolactate by alpha-acetolactate synthase, then decarboxylated to acetoin by this enzyme. Acetoin can be reduced in some species to 2,3-butanediol by acetoin reductase. [Energy metabolism, Fermentation].	1.81642e-136
NC_022898.1\|WP_003227859.1\|3529351_3530260_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176143	cd08452, PBP2_AlsR, The C-terminal substrate binding domain of LysR-type trnascriptional regulator AlsR, which regulates acetoin formation under stationary phase growth conditions; contains the type 2 periplasmic binding fold. AlsR is responsible for activating the expression of the acetoin operon (alsSD) in response to inducing signals such as glucose and acetate. Like many other LysR family proteins, AlsR is transcribed divergently from the alsSD operon. The alsS gene encodes acetolactate synthase, an enzyme involved in the production of acetoin in cells of stationary-phase. AlsS catalyzes the conversion of two pyruvate molecules to acetolactate and carbon dioxide. Acetolactate is then converted to acetoin at low pH by acetolactate decarboxylase which encoded by the alsD gene. Acetoin is an important physiological metabolite excreted by many microorganisms grown on glucose or other fermentable carbon sources. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.7247e-130
NC_022898.1\|WP_003242900.1\|3538778_3539255_+\|chromate-efflux-transcriptional-regulator-ChrS	gnl\|CDD\|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	4.48628e-37
NC_022898.1\|WP_009968282.1\|3523018_3523987_+\|ribose-ABC-transporter-permease	gnl\|CDD\|181922	PRK09512, rbsC, ribose ABC transporter permease protein; Reviewed.	2.96133e-116
NC_022898.1\|WP_003242760.1\|3523998_3524916_+\|ribose-ABC-transporter-substrate-binding-protein-RbsB	gnl\|CDD\|380546	cd06323, PBP1_ribose_binding, periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs. Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis D-ribose binding protein (ttRBP) and its mesophilic homologs. Members of this group belong to the type 1 periplasmic binding protein superfamily, whose members are involved in chemotaxis, ATP-binding cassette transport, and intercellular communication in central nervous system. The thermophilic and mesophilic ribose-binding proteins are structurally very similar, but differ substantially in thermal stability.	2.81146e-138
NC_022898.1\|WP_003243596.1\|3524997_3525534_+\|SH3-domain-containing-protein	gnl\|CDD\|214600	smart00287, SH3b, Bacterial SH3 domain homologues.	1.32357e-11
NC_022898.1\|WP_003227847.1\|3536987_3538565_-\|gamma-glutamyltransferase	gnl\|CDD\|129176	TIGR00066, Contains:_Gamma-glutamyltranspeptidase_large_chain, gamma-glutamyltranspeptidase. Also called gamma-glutamyltranspeptidase (ggt). Some members of this family have antibiotic synthesis or resistance activities. In the case of a cephalosporin acylase from Pseudomonas sp., the enzyme was shown to retain some gamma-glutamyltranspeptidase activity. Other, more distantly related proteins have ggt-related activities and score below the trusted cutoff. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	0
NC_022898.1\|WP_010886626.1\|3530470_3531799_+\|arsenic-transporter	gnl\|CDD\|238538	cd01118, ArsB_permease, Anion permease ArsB. These permeases have been shown to export arsenate and antimonite in eubacteria and archaea. A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a channel-forming subunit of an ATP-driven anion pump (ArsAB). The ArsAB complex is similar in many ways to ATP-binding cassette transporters, which have two groups of six transmembrane-spanning helical segments and two nucleotide-binding domains. The ArsB proteins belong to the ArsB/NhaD superfamily of permeases that translocate sodium, arsenate, sulfate, and organic anions across biological membranes in all three kingdoms of life.	5.48885e-104

>NC_022898.1|WP_003242695.1|3531855_3532533_-|DUF2642-domain-containing-protein
MKGLNQFLNTDVEVVISGDTRFVGTLIDIGQDIFVIFDGCNYLYIPLLHLHQINKAKIVTSTEKPFLINPEDPMIEAETQAFSYRNTLNKVKGQFIEVYVTGGRSIHGYVTNVLNDYIVFFSPVFKILFISMHHLKWFTPYSTEQTPYTLDNSQLPVVPSKVPLVRNFEEQIKKNIGELVIFDMGEVPEKVGLLKGVSNNIIELINASGEPVIWKLNHLKTMHLP
>NC_022898.1|WP_010886626.1|3530470_3531799_+|arsenic-transporter
MLAFFVTMIFIFWRPKGLNEAIPATFGALMVLLCGSVSLADLGEIGTKVTGASVTILATMIMAIALESFGFFYWVAAKLLQQSKGSGIKLFWLTNLLCFLMTIFLNNDGSILITTPILLLVLKYLGLKKHQKAPYLLSGVLIATASSAPIGVSNIVNLISLKIIGMDLYLHTAMMFVPSMMGLIFMTCLLFMFFYKRLPKSLPDIPGHFQSLRHRRYHPLHSPSAPLPERNQTKIMLFVLAFVFLVRMSLFAASYTGISVPLVAVIGSFILLSWRWIYFKTSPRDLLYKSPWHIFIFAFTMYVLIYGLHNIGFTELLVSYFEPVVSGSLAHATFASGISTSVFSNLFNNHPALMISTFTLTEMTLNPSTTKIIYLANIIGSDIGSLLLPMGTLATLIWMHILKQHDESISWGEYIKTTIIIIPLTVLFTLTCLYFWISWLFL
>NC_022898.1|WP_003227859.1|3529351_3530260_+|LysR-family-transcriptional-regulator
MELRHLQYFIAVAEELHFGKAARRLNMTQPPLSQQIKQLEEEVGVTLLKRTKRFVELTAAGEIFLNHCRMALMQIGQGIELAQRTARGEQGLLVIGFVGSATYEFLPPIVREYRKKFPSVKIELREISSSRQQEELLKGNIDIGILHPPLQHTALHIETAQSSPCVLALPKQHPLTSKESITIEDLRDEPIITVAKEAWPTLYMDFIQFCEQAGFRPNIVQEATEYQMVIGLVSAGIGMTFVPSSAKKLFNLDVTYRKMDQIQLNAEWVIAYRKDNHNPLIKHFIHISNCQQTRTKESDAGT
>NC_022898.1|WP_003244057.1|3527481_3529194_-|acetolactate-synthase-AlsS
MTKATKEQKSLVKNRGAELVVDCLVEQGVTHVFGIPGAKIDAVFDALQDKGPEIIVARHEQNAAFMAQAVGRLTGKPGVVLVTSGPGASNLATGLLTANTEGDPVVALAGNVIRADRLKRTHQSLDNAALFQPITKYSVEVQDVKNIPEAVTNAFRIASAGQAGAAFVSFPQDVVNEVTNTKNVRAVAAPKLGPAADDAISAAIAKIQTAKLPVVLVGMKGGRPEAIKAVRKLLKKVQLPFVETYQAAGTLSRDLEDQYFGRIGLFRNQPGDLLLEQADVVLTIGYDPIEYDPKFWNINGDRTIIHLDEIIADIDHAYQPDLELIGDIPSTINHIEHDAVKVEFAEREQKILSDLKQYMHEGEQVPADWKSDRAHPLEIVKELRNAVDDHVTVTCDIGSHAIWMSRYFRSYEPLTLMISNGMQTLGVALPWAIGASLVKPGEKVVSVSGDGGFLFSAMELETAVRLKAPIVHIVWNDSTYDMVAFQQLKKYNRTSAVDFGNIDIVKYAESFGATGLRVESPDQLADVLRQGMNAEGPVIIDVPVDYSDNINLASDKLPKEFGELMKTKAL
>NC_022898.1|WP_003244457.1|3526652_3527420_-|acetolactate-decarboxylase
MKRESNIQVLSRGQKDQPVSQIYQVSTMTSLLDGVYDGDFELSEIPKYGDFGIGTFNKLDGELIGFDGEFYRLRSDGTATPVQNGDRSPFCSFTFFTPDMTHKIDAKMTREDFEKEINSMLPSRNLFYAIRIDGLFKKVQTRTVELQEKPYVPMVEAVKTQPIFNFDNVRGTIVGFLTPAYANGIAVSGYHLHFIDEGRNSGGHVFDYVLEDCTVTISQKMNMNLRLPNTADFFNANLDNPDFAKDIETTEGSPE
>NC_022898.1|WP_003242788.1|3526025_3526553_-|NAD(P)H-dependent-oxidoreductase
MKILVLAVHPHMETSVVNKAWAEELSKHDNITVRDLYKEYPDEAIDVAKEQQLCEEYDRIVFQFPLYWYSSPPLLKKWQDLVLTYGWAFGSEGNALHGKELMLAVSTGSEAEKYQAGGANHYSISELLKPFQATSNLIGMKYLPPYVFYGVNYAAAEDISHSAKRLAEYIQQPFV
>NC_022898.1|WP_003243460.1|3525689_3525986_+|DUF3892-domain-containing-protein
MDQFEAAYESYKARQTTADQENVPSGKEEIIAVRRNEEDNIIAVKTNTGRELDYPTALSEAKSGKLAHVDVFHKYGRDILRSEPDGIKENNLSELPDF
>NC_022898.1|WP_003243596.1|3524997_3525534_+|SH3-domain-containing-protein
MNKPTKLFSTLALAAGMTAAAAGGAGTIHAQQPETTVSIDDLYSYPIDSYLVSAEALNVRTKPSASSQKADTLHLGDSLKLISFSNADWAKVKYKNGKTGFVSTHYIVKAATTVKTKTKTKVYTSADGKSIKTLPADTSVSFLGWSKTNKGGFDFDWVFVDYGGTTGYMKTKDLHMTK
>NC_022898.1|WP_003242760.1|3523998_3524916_+|ribose-ABC-transporter-substrate-binding-protein-RbsB
MKKAVSVILTLSLFLLTACSLEPPQWAKPSNSGNKKEFTIGLSVSTLNNPFFVSLKKGIEKEAKKRGMKVIIVDAQNDSSKQTSDVEDLIQQGVDALLINPTDSSAISTAVESANAVGVPVVTIDRSAEQGKVETLVASDNVKGGEMAAAFIADKLGKGAKVAELEGVPGASATRERGSGFHNIADQKLQVVTKQSADFDRTKGLTVMENLLQGHPDIQAVFAHNDEMALGALEAINSSGKDILVIGFDGNKDALASIKDRKLSATVAQQPELIGKLATEAADDILHGKKVQKTISAPLKLETQK
>NC_022898.1|WP_009968282.1|3523018_3523987_+|ribose-ABC-transporter-permease
MKTEQLQTEQKRIHFDGVMQKLGPFLGLFILVIIVSILNPSFLEPLNILNLLRQVAINGLIAFGMTFVILTGGIDLSVGAILALSSALVAGMIVSGVDPVLAIILGCIIGAVLGMINGLLITKGKMAPFIATLATMTVFRGLTLVYTDGNPITGLGTNYGFQMFGRGYFLGIPVPAITMVLAFVILWVLLHKTPFGRRTYAIGGNEKAALISGIKVTRVKVMIYSLAGLLSALAGAILTSRLHSAQPTAGESYELDAIAAVVLGGTSLSGGRGRIVGTLIGVLIIGTLNNGLNLLGVSSFYQLVVKGIVILIAVLLDRKKSA
>NC_022898.1|WP_003227854.1|3533862_3534951_-|spore-coat-protein-CotH
MKNQSNLPLYQLFVHPKDLRELKKDIWDDDPVPAVMKVNQKRLDIDIAYRGSHIRDFKKKSYHISFYQPKTFRGAREIHLNAEYKDPSLMRNKLSLDFFSELGTLSPKAEFAFVKMNGKNEGVYLELESVDEYYLAKRKLADGAIFYAVDDDANFSLMSDLERETKTSLELGYEKKTGTEEDDFYLQDMIFKINTVPKAQFKSEVTKHVDVDKYLRWLAGIVFTSNYDGFVHNYALYRSGETGLFEVIPWDYDATWGRDIHGERMAADYVRIQGFNTLTARILDESEFRKSYKRLLEKTLQSLFTIEYMEPKIMAMYERIRPFVLMDPYKKNDIERFDREPDVICEYIKNRSQYLKDHLSIL
>NC_022898.1|WP_010886627.1|3535091_3535679_+|spore-coat-protein-CotG
MGHYSHSDIEEAVKSAKKEGLKDYLYQEPHGKKRSHKKSHRTHKKSRSHKKSYCSHKKSRSHKKSFCSHKKSRSHKKSYCSHKKSRSHKKSYRSHKKSRSYKKSYRSYKKSRSYKKSCRSYKKSRSYKKSYCSHKKKSRSYKKSCRTHKKSYRSHKKYYKKPHHHCDDYKRHDDYDSKKEYWKDGNCWVVKKKYK
>NC_022898.1|WP_003227852.1|3535852_3536470_+|flavin-reductase-family-protein
MYIFQADQLSAKDTYKLLSGTVIPRPIAFVTTLSSGGAVNAAPFSFYNVVSSDPPLLSISVNRTEGRQKDTARNAVENGEFVVHVSDEAIIEDINETAASLRPDESELTRTSLHPVESKAVSVPGIKEARVRFECKLERHITFDNDQGITTADLLIGRVVCFHLDEKVYDAEKGYILTDELKPASRLAGNHYAKLGEEFTLIRPS
>NC_022898.1|WP_003227850.1|3536647_3536983_+|DUF4181-domain-containing-protein
MTNFWILMLIAITISLASQFFIKKKYGIDKSGWRYKHVSNTHKWIEITLLILFVFSLSFFPVEYLLLLFFIVIDSIRIFMEWHYRPEDKQYMYHIVEVSLMFMLLIYVCTL
>NC_022898.1|WP_003227847.1|3536987_3538565_-|gamma-glutamyltransferase
MNKSVIGTKQMVVSPHYLASQAGNRILDKGGNAFDAAVAVSACLAVVYPHMTGLGGDSFWLTFHQETKAVKVYNGSGRSGKNVTRDVYKGKSAIPLRGIDSAITVPGMVDSWDAVLKEYGRLSLADVLEPARDYAQNGFPVSADQCRHTEKNIELLASTPYTADIFTRRGKAPVPGERFVQKELADSLNLIAEKGRSAFYEGDLAQRIVSHLQNNGSYMTIDDFKAHRGEWAAPVSSDYRGYSVYQAPPNSQGFTGLLTLNILENYDFTQIEHGSFEYYHVLVEALKKSFLDRDAVLTDPAFADIPLERLLDKRYAKQLAEEIGYLAIPAESRPVGSDTAYAAVIDADGNAVSFIQSLYFEFGSAVTAGDTGILLQNRGSFFSLDENHVNTLEPRKRTFHTLMPAMVCKGGKPKILYGTQGGEGQPQTQTAIITRMLDYGMHPQQAISEPRWVWGRTWGEEYEGLRVEGRFTDKTIQKLKDSGHLVEVVGDYDPLMGQAAAIKVDEEGFLQGGADPRGDGAAVGI
>NC_022898.1|WP_003242900.1|3538778_3539255_+|chromate-efflux-transcriptional-regulator-ChrS
MSHEYQIPNLVLDETDKQILTILHEEGRISYTDLGKRVDLSRVAVQARINQLIEAGVIEKFTAVINPAKIGIHVSVFFNVEVEPQFLEEVALKLEEEPAVTSLYHMTGPSKLHMHGIFTNDQEMEEFLTKRLYPLRGVVSVDCQMLIKRYKSRMGMKL
>NC_022898.1|WP_003227843.1|3539268_3539862_+|chromate-efflux-transporter-subunit-ChrB
MKNHPYRDMTAAMVRTGILGFGGGPSVIPLIRHEAVNKYKWIDDDEFGEILAIANALPGPIATKMAAYLGFKLKGTLGAIVAILAHILPTCLAMVGLFAAVNVLSHSAIVAGMIGAVTPVIAVMLGIMAYEFGQKALKGFGWVTGILFFIIAFIGLQTLQINPGLVIIIFLAYGAFHFKLKDKITNKHSKDKGMSAS
>NC_022898.1|WP_003227840.1|3539858_3540395_+|chromate-resistance-efflux-protein-ChrA
MISIYLFMAFFIANLLGYGGGPASIPLMFEEVVNRYSWLSNDQFSNMLALANALPGPIATKIAAYVGYSAGGWPGFLIALIATVVPSALALIVLLRIIQRFRQSPVIKGMTLSVQPVIAVMMLILTWQIGADGIKAIGWVQSIVITGISLLAMTKFKMHPAFLIIAAFLYGGLVIPYL
>NC_022898.1|WP_003243378.1|3540421_3540643_-|hypothetical-protein
MKFLLSVIAGLLILALYLFWKVQPPVWIQVETNSSQLKQSVRMAGTTLQVKHMIKSDAGEETAVISNGISGLK
>NC_022898.1|WP_003242945.1|3540639_3541185_-|flavodoxin-family-protein
MKIAVINGGTRSGGNTDVLAEKAVQGFDAEHIYLQKYPIQPIEDLRHAQGGFRPVQDDYDSIIERILQCHILIFATPIYWFGMSGTLKLFIDRWSQTLRDPRFPDFKQQMSVKQAYVIAVGGDNPKIKGLPLIQQFEHIFHFMGMSFKGYVLGEGNRPGDILRDHQALSAASRLLKRSDAI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_022898_2	2.1\|2990135\|60\|NC_022898\|CRISPRCasFinder	2990135-2990194	60	NZ_CP024037	Bacillus aryabhattai strain K13 plasmid unnamed2	10417-10476	7	0.883
NC_022898_2	2.1\|2990135\|60\|NC_022898\|CRISPRCasFinder	2990135-2990194	60	NZ_CP026740	Bacillus megaterium strain YC4-R4 plasmid unnamed4	70764-70823	7	0.883
NC_022898_2	2.1\|2990135\|60\|NC_022898\|CRISPRCasFinder	2990135-2990194	60	NC_017139	Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence	1318-1377	7	0.883
NC_022898_2	2.1\|2990135\|60\|NC_022898\|CRISPRCasFinder	2990135-2990194	60	NZ_CP010587	Bacillus megaterium Q3 plasmid p1, complete sequence	838-897	7	0.883
NC_022898_2	2.1\|2990135\|60\|NC_022898\|CRISPRCasFinder	2990135-2990194	60	NZ_CP023319	Bacillus megaterium strain A plasmid p2, complete sequence	75825-75884	7	0.883
NC_022898_2	2.1\|2990135\|60\|NC_022898\|CRISPRCasFinder	2990135-2990194	60	NC_020451	Vibrio coralliilyticus strain ATCC BAA-450 plasmid, complete sequence	1960-2019	9	0.85
NC_022898_2	2.1\|2990135\|60\|NC_022898\|CRISPRCasFinder	2990135-2990194	60	NZ_CP015440	Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_2, complete sequence	64773-64832	12	0.8
NC_022898_2	2.1\|2990135\|60\|NC_022898\|CRISPRCasFinder	2990135-2990194	60	NZ_CP033045	Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence	483791-483850	13	0.783
NC_022898_2	2.1\|2990135\|60\|NC_022898\|CRISPRCasFinder	2990135-2990194	60	NZ_LR134399	Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence	57361-57420	14	0.767

1. spacer 2.1|2990135|60|NC_022898|CRISPRCasFinder matches to NZ_CP024037 (Bacillus aryabhattai strain K13 plasmid unnamed2) position: , mismatch: 7, identity: 0.883

cagcttggaaggctgaggttttaccactaaactacacccgcaatttttatttggggcgat	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatatttta-aagtggcggt	Protospacer
******************************************  *****   * ****.*

2. spacer 2.1|2990135|60|NC_022898|CRISPRCasFinder matches to NZ_CP026740 (Bacillus megaterium strain YC4-R4 plasmid unnamed4) position: , mismatch: 7, identity: 0.883

cagcttggaaggctgaggttttaccactaaactacacccgcaatttttatttggggcgat	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatatttta-aagtggcggt	Protospacer
******************************************  *****   * ****.*

3. spacer 2.1|2990135|60|NC_022898|CRISPRCasFinder matches to NC_017139 (Bacillus megaterium WSH-002 plasmid WSH-002_p1, complete sequence) position: , mismatch: 7, identity: 0.883

cagcttggaaggctgaggttttaccactaaactacacccgcaatttttatttggggcgat	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatatttta-aagtggcggt	Protospacer
******************************************  *****   * ****.*

4. spacer 2.1|2990135|60|NC_022898|CRISPRCasFinder matches to NZ_CP010587 (Bacillus megaterium Q3 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.883

cagcttggaaggctgaggttttaccactaaactacacccgcaatttttatttggggcgat	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatatttta-aagtggcggt	Protospacer
******************************************  *****   * ****.*

5. spacer 2.1|2990135|60|NC_022898|CRISPRCasFinder matches to NZ_CP023319 (Bacillus megaterium strain A plasmid p2, complete sequence) position: , mismatch: 7, identity: 0.883

cagcttggaaggctgaggttttaccactaaactacacccgcaatttttatttggggcgat	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatatttta-aagtggcggt	Protospacer
******************************************  *****   * ****.*

6. spacer 2.1|2990135|60|NC_022898|CRISPRCasFinder matches to NC_020451 (Vibrio coralliilyticus strain ATCC BAA-450 plasmid, complete sequence) position: , mismatch: 9, identity: 0.85

cagcttggaaggctgaggttttaccactaaactacacccgcaatttttatttggggcgat	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcattttagttatggcccggg	Protospacer
****************************************** ***   * ***  **.

7. spacer 2.1|2990135|60|NC_022898|CRISPRCasFinder matches to NZ_CP015440 (Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_2, complete sequence) position: , mismatch: 12, identity: 0.8

cagcttggaaggctgaggttttaccactaaactacacccgca-------atttttatttg	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcataataatatataccattg	Protospacer
******************************************       ** * .  ***

8. spacer 2.1|2990135|60|NC_022898|CRISPRCasFinder matches to NZ_CP033045 (Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence) position: , mismatch: 13, identity: 0.783

cagcttggaaggctgaggttttaccactaaactacacccgc--------aatttttattt	CRISPR spacer
cagcttggaaggctgaggttttaccactaaactacacccgcatggttaaaagttttgcca	Protospacer
*****************************************        ** ****...

9. spacer 2.1|2990135|60|NC_022898|CRISPRCasFinder matches to NZ_LR134399 (Listeria monocytogenes strain NCTC7974 plasmid 2, complete sequence) position: , mismatch: 14, identity: 0.767

cagcttggaaggctgaggttttaccactaaactacacccgc---------aatttttatt	CRISPR spacer
cagcttggaaggctgtagttttaccactaaactacacccgcatagtaagtagttcttagt	Protospacer
*************** .************************         *.**.*** *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

663265 : 671631

Synechococcus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003233955.1\|663265_664561_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	5.9e-19	25.7
WP_003242871.1\|664634_665360_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3G7P8	Synechococcus_phage	7.0e-46	44.1
WP_003219409.1\|665352_665607_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003243954.1\|665603_666287_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003244429.1\|666270_668499_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	3.8e-159	40.1
WP_003233947.1\|668474_669905_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.2e-52	32.5
WP_003242485.1\|670006_671047_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.1e-63	41.7
WP_003244322.1\|671043_671631_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.0e-28	40.4

DBSCAN-SWA_2

1170851 : 1214624

Planktothrix_phage(25.0%)

coat,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003232972.1\|1170851_1171091_-\|coat	spore coat protein YjzB	NA	NA	NA	NA
WP_003232971.1\|1171255_1172194_+	beta-ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_003244890.1\|1172216_1173458_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_003232967.1\|1173533_1174319_+	DUF2268 domain-containing protein	NA	NA	NA	NA
WP_003232965.1\|1174510_1175497_+	oligopeptide ABC transporter ATP-binding protein AppD	G9BWD6	Planktothrix_phage	5.7e-22	32.9
WP_003232964.1\|1175493_1176483_+	oligopeptide ABC transporter ATP-binding protein AppF	F2Y302	Organic_Lake_phycodnavirus	6.7e-07	26.1
WP_003245828.1\|1178276_1179227_+	oligopeptide ABC transporter permease AppB	NA	NA	NA	NA
WP_003232961.1\|1179243_1180155_+	oligopeptide ABC transporter permease AppC	NA	NA	NA	NA
WP_003239298.1\|1180359_1181112_+	YjbA family protein	A0A0A0RP53	Bacillus_phage	5.4e-49	43.9
WP_003245134.1\|1181146_1182139_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_003232957.1\|1182882_1184520_+	oligopeptide ABC transporter substrate-binding protein OppA	NA	NA	NA	NA
WP_003245554.1\|1184627_1185563_+	oligopeptide ABC transporter permease OppB	NA	NA	NA	NA
WP_003232954.1\|1185566_1186484_+	oligopeptide ABC transporter permease OppC	NA	NA	NA	NA
WP_014906294.1\|1186488_1187565_+	oligopeptide ABC transporter ATP-binding protein OppD	G9BWD6	Planktothrix_phage	2.1e-17	30.8
WP_003245567.1\|1187566_1188484_+	oligopeptide ABC transporter ATP-binding protein OppF	M1HP82	Acanthocystis_turfacea_Chlorella_virus	1.2e-05	24.6
WP_010886478.1\|1188590_1189808_+	MFS transporter	NA	NA	NA	NA
WP_003244921.1\|1189971_1190550_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003245483.1\|1190730_1191126_+	transcriptional regulator Spx	NA	NA	NA	NA
WP_003232944.1\|1191168_1191825_-	TerC family protein	A0A2R2YAT9	Pseudomonas_phage	1.1e-29	38.0
WP_119122854.1\|1191994_1192135_+	hypothetical protein	NA	NA	NA	NA
WP_003245194.1\|1192101_1192758_+	adaptor protein MecA	NA	NA	NA	NA
WP_003245684.1\|1192752_1192875_-	hypothetical protein	NA	NA	NA	NA
WP_003245839.1\|1192918_1194070_+	competence protein CoiA	NA	NA	NA	NA
WP_009967010.1\|1194116_1196129_+	oligoendopeptidase F	NA	NA	NA	NA
WP_003244944.1\|1196166_1196334_-	hypothetical protein	NA	NA	NA	NA
WP_003245184.1\|1196647_1197547_-	adaptor protein SpxH	NA	NA	NA	NA
WP_003232928.1\|1197543_1197942_-	group 2 truncated hemoglobin YjbI	NA	NA	NA	NA
WP_010886480.1\|1198196_1198742_-	bifunctional muramidase/murein lytic transglycosylase	A0A1P8CWQ1	Bacillus_phage	4.8e-39	60.4
WP_003232924.1\|1198945_1199518_-	CYTH domain-containing protein	NA	NA	NA	NA
WP_003232922.1\|1199642_1200011_+	hypothetical protein	NA	NA	NA	NA
WP_003245294.1\|1200039_1200675_+	GTP diphosphokinase	NA	NA	NA	NA
WP_003232918.1\|1200693_1201494_+	NAD kinase	NA	NA	NA	NA
WP_010886481.1\|1201556_1202408_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_003244765.1\|1202420_1203155_-	bis(5'-nucleosyl)-tetraphosphatase PrpE	M4Q4T6	Vibrio_phage	3.2e-06	25.0
WP_003232910.1\|1203389_1205234_+	sodium:proton antiporter	NA	NA	NA	NA
WP_003232909.1\|1205482_1206193_+	thiaminase II	NA	NA	NA	NA
WP_003232908.1\|1206167_1206785_+	thiazole tautomerase TenI	NA	NA	NA	NA
WP_003245044.1\|1206768_1207878_+	glycine oxidase ThiO	NA	NA	NA	NA
WP_010886482.1\|1207877_1208078_+	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_010886483.1\|1208074_1208845_+	thiazole synthase	NA	NA	NA	NA
WP_003245868.1\|1208841_1209852_+	thiazole biosynthesis adenylyltransferase ThiF	NA	NA	NA	NA
WP_003245050.1\|1209870_1210686_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_023592761.1\|1210821_1211598_+	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_010886484.1\|1211698_1212382_+\|coat	spore coat protein CotO	NA	NA	NA	NA
WP_003244982.1\|1212475_1212922_-\|coat	spore coat protein CotZ	NA	NA	NA	NA
WP_003239243.1\|1213049_1213538_-\|coat	spore coat protein CotY	NA	NA	NA	NA
WP_003244668.1\|1213689_1214208_-\|coat	spore coat protein CotX	NA	NA	NA	NA
WP_003245818.1\|1214306_1214624_-\|coat	spore coat protein CotW	NA	NA	NA	NA

DBSCAN-SWA_3

1277486 : 1311219

uncultured_Caudovirales_phage(29.41%)

portal,tail,holin,plate,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003245490.1\|1277486_1278758_+	ATPase YjoB	A0A1V0SEI6	Indivirus	8.6e-15	37.1
WP_010886491.1\|1278902_1280039_+	response regulator aspartate phosphatase RapA	A0A1P8CWN8	Bacillus_phage	8.3e-94	47.4
WP_003245487.1\|1280028_1280163_+	phosphatase RapA inhibitor PhrA	NA	NA	NA	NA
WP_003232731.1\|1280193_1280451_-	YciI family protein	NA	NA	NA	NA
WP_003244876.1\|1280571_1281525_+	LysM peptidoglycan-binding domain-containing protein	A0A218KC88	Bacillus_phage	7.3e-67	74.1
WP_003245254.1\|1281564_1281942_-	PH domain-containing protein	A5GYQ0	Lactococcus_phage	6.1e-17	42.3
WP_003244789.1\|1282047_1282650_+	poly-gamma-glutamate hydrolase family protein	F8WQ53	Bacillus_phage	3.8e-45	49.2
WP_003245071.1\|1282726_1283563_+	manganese catalase	NA	NA	NA	NA
WP_003232721.1\|1283606_1284203_-	ImmA/IrrE family metallo-endopeptidase	A0A2H4JA43	uncultured_Caudovirales_phage	8.1e-40	51.7
WP_003232719.1\|1284365_1284707_-	helix-turn-helix transcriptional regulator	A0A2H4J6F9	uncultured_Caudovirales_phage	1.3e-18	45.8
WP_003232712.1\|1284884_1285064_+	hypothetical protein	NA	NA	NA	NA
WP_003245799.1\|1285050_1285887_+	phage-like element PBSX protein XkdB	S6BFM4	Thermus_phage	1.8e-24	28.2
WP_010886492.1\|1285786_1286587_+	ATP-binding protein	A6XMI1	Bacillus_virus	5.0e-61	51.7
WP_003245588.1\|1286586_1286754_+	hypothetical protein	NA	NA	NA	NA
WP_003245290.1\|1286838_1287189_+	phage-like element PBSX protein XkdD	NA	NA	NA	NA
WP_003244900.1\|1287185_1287392_+	phage-like element PBSX protein XtrA	A0A2H4J4M6	uncultured_Caudovirales_phage	1.6e-11	50.0
WP_003245797.1\|1287507_1288017_+	sigma-70 family RNA polymerase sigma factor	A0A1L2JY33	Aeribacillus_phage	1.9e-21	38.6
WP_003244697.1\|1288132_1288930_+\|terminase	PBSX phage terminase small subunit	A0A0S2MVB6	Bacillus_phage	8.0e-59	50.2
WP_003245584.1\|1288926_1290228_+\|terminase	PBSX family phage terminase large subunit	A0A2P1JTW5	Anoxybacillus_phage	2.4e-153	60.2
WP_003245427.1\|1290231_1291719_+\|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	1.7e-139	55.7
WP_003245836.1\|1291738_1292566_+	phage-like element PBSX protein XkdF	A0A1B1P7E4	Bacillus_phage	2.1e-54	58.7
WP_003232690.1\|1292591_1293527_+	phage-like element PBSX protein XkdG	A0A1B1P7E3	Bacillus_phage	1.1e-104	63.8
WP_003245011.1\|1293548_1293932_+	DUF3199 family protein	A0A1B1P7D6	Bacillus_phage	1.9e-13	40.2
WP_009967053.1\|1293928_1294285_+	YqbH/XkdH family protein	NA	NA	NA	NA
WP_003245226.1\|1294281_1294767_+	HK97 gp10 family phage protein	A0A249XXA4	Clostridium_phage	2.1e-38	47.0
WP_003232680.1\|1294779_1295220_+	phage-like element PBSX protein XkdJ	NA	NA	NA	NA
WP_003232679.1\|1295223_1295442_+	hypothetical protein	NA	NA	NA	NA
WP_003245369.1\|1295438_1296839_+	phage-like element PBSX protein XkdK	A0A0A7S087	Clostridium_phage	2.3e-77	39.3
WP_003232677.1\|1296840_1297284_+\|tail	phage tail tube protein	A0A0K2CNG3	Brevibacillus_phage	8.4e-26	45.2
WP_003232676.1\|1297375_1297822_+	phage-like element PBSX protein XkdN	A0A249XXA9	Clostridium_phage	7.5e-14	33.6
WP_003239113.1\|1297851_1298001_+	hypothetical protein	NA	NA	NA	NA
WP_010886493.1\|1298002_1302001_+	transglycosylase SLT domain-containing protein	A0A1L2JY60	Aeribacillus_phage	2.1e-43	44.9
WP_003232674.1\|1301993_1302653_+	LysM peptidoglycan-binding domain-containing protein	A0A090DBR9	Clostridium_phage	3.7e-25	34.0
WP_003245730.1\|1302668_1303646_+	phage-like element PBSX protein XkdQ	H7BV96	unidentified_phage	1.0e-39	32.6
WP_003244812.1\|1303645_1303912_+	DUF2577 family protein	S6C459	Thermus_phage	1.7e-05	36.4
WP_003232671.1\|1303968_1304394_+	DUF2634 domain-containing protein	A0A2H4J6K5	uncultured_Caudovirales_phage	7.8e-13	38.0
WP_009967060.1\|1304386_1305433_+\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	4.4e-73	44.3
WP_003244743.1\|1305416_1305995_+	YmfQ family protein	A0A2H4J717	uncultured_Caudovirales_phage	3.0e-15	34.2
WP_003232665.1\|1305991_1306264_+	hypothetical protein	NA	NA	NA	NA
WP_003244681.1\|1306266_1308330_+	phage-like element PBSX protein XkdV	A0A2H4J4R1	uncultured_Caudovirales_phage	4.8e-31	37.4
WP_003232660.1\|1308341_1308671_+	phage-like element PBSX protein XkdW	A0A2H4JCI0	uncultured_Caudovirales_phage	1.7e-15	41.3
WP_003232658.1\|1308667_1308832_+	XkdX family protein	A0A2H4JAA1	uncultured_Caudovirales_phage	3.2e-15	66.0
WP_003245597.1\|1308875_1309715_+	phage-like element PBSX protein XepA	NA	NA	NA	NA
WP_003232655.1\|1309767_1310037_+	hypothetical protein	A0A2H4JD40	uncultured_Caudovirales_phage	6.2e-24	64.8
WP_003232653.1\|1310049_1310313_+\|holin	phage holin	A0A2H4J6M0	uncultured_Caudovirales_phage	4.7e-24	65.5
WP_003245230.1\|1310325_1311219_+	LysM peptidoglycan-binding domain-containing protein	Q9ZXD7	Bacillus_phage	1.8e-83	69.7

DBSCAN-SWA_4

1831654 : 1838209

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003231758.1\|1831654_1832047_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	G3MBF1	Bacillus_virus	2.5e-29	58.3
WP_003245700.1\|1832006_1834109_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	U5PY35	Bacillus_phage	0.0e+00	87.0
WP_003231754.1\|1834126_1835116_+	class 1b ribonucleoside-diphosphate reductase subunit beta	F8WQ21	Bacillus_phage	1.9e-155	83.5
WP_003245105.1\|1835165_1835786_+	hypothetical protein	A0A127AYS1	Bacillus_phage	1.6e-46	48.4
WP_003244862.1\|1835849_1836617_-	sporulation-specific N-acetylmuramoyl-L-alanine amidase	E5DV68	Deep-sea_thermophilic_phage	9.1e-52	49.5
WP_003231746.1\|1837240_1838209_+	stage V sporulation protein K	G3MAX6	Bacillus_virus	5.2e-52	40.5

DBSCAN-SWA_5

2011945 : 2017632

Bacillus_phage(100.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003231348.1\|2011945_2012119_-	hypothetical protein	A0A1P8CWY7	Bacillus_phage	5.6e-18	82.5
WP_009967407.1\|2012263_2012488_+	hypothetical protein	A0A1P8CWZ1	Bacillus_phage	8.9e-16	82.0
WP_003231345.1\|2012491_2012947_-	hypothetical protein	NA	NA	NA	NA
WP_010886526.1\|2013071_2013332_+	hypothetical protein	NA	NA	NA	NA
WP_075058859.1\|2014085_2014250_+\|holin	phage holin	A0A1P8CWN5	Bacillus_phage	3.9e-21	92.6
WP_003231340.1\|2014404_2015520_+	response regulator aspartate phosphatase RapK	D6R410	Bacillus_phage	1.5e-95	49.2
WP_004399440.1\|2015516_2015639_+	phosphatase RapK inhibitor PhrK	NA	NA	NA	NA
WP_003231333.1\|2016794_2017088_-	YolD-like family protein	O64030	Bacillus_phage	7.5e-39	86.6
WP_009967409.1\|2017296_2017632_+	hypothetical protein	A0A1P8CWM9	Bacillus_phage	7.2e-46	86.5

DBSCAN-SWA_6

2243115 : 2249211

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003223904.1\|2243115_2243709_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.0e-14	35.4
WP_003246108.1\|2243698_2244454_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	5.5e-09	29.2
WP_003230498.1\|2244734_2245259_+	DUF309 domain-containing protein	NA	NA	NA	NA
WP_003223910.1\|2245272_2245647_-	GNAT family N-acetyltransferase RibT	NA	NA	NA	NA
WP_003223915.1\|2245759_2246224_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.5e-44	60.0
WP_004398484.1\|2246256_2247453_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.9e-115	54.9
WP_004398505.1\|2247467_2248115_-	riboflavin synthase subunit alpha	A0A2H4PQS5	Staphylococcus_phage	5.0e-43	45.9
WP_004398763.1\|2248125_2249211_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.1e-56	36.1

DBSCAN-SWA_7

2478955 : 2517097

uncultured_Caudovirales_phage(30.3%)

portal,tail,holin,plate,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004399034.1\|2478955_2480551_+	type II toxin-antitoxin system toxin ribonuclease YqcG	A0A1P8CWI7	Bacillus_phage	6.9e-78	61.3
WP_009967790.1\|2480565_2481144_+	type II toxin-antitoxin system antitoxin YqcF	NA	NA	NA	NA
WP_009967791.1\|2481261_2481408_+	hypothetical protein	NA	NA	NA	NA
WP_003229947.1\|2481404_2481767_-	hypothetical protein	NA	NA	NA	NA
WP_004399085.1\|2481782_2482262_-	hypothetical protein	NA	NA	NA	NA
WP_003229946.1\|2482426_2483245_-	N-acetylmuramoyl-L-alanine amidase	A0A218KC88	Bacillus_phage	1.0e-64	74.4
WP_003246208.1\|2483289_2483712_-\|holin	holin family protein	D6R405	Bacillus_phage	3.3e-48	73.7
WP_003246010.1\|2483756_2484650_-	hypothetical protein	NA	NA	NA	NA
WP_003229944.1\|2484737_2484902_-	XkdX family protein	A0A2H4JAA1	uncultured_Caudovirales_phage	2.7e-14	67.9
WP_009967793.1\|2484898_2485234_-\|portal	phage portal protein	NA	NA	NA	NA
WP_003229943.1\|2485243_2486344_-	hypothetical protein	M4ZRP1	Bacillus_phage	1.7e-19	56.1
WP_003229942.1\|2486346_2486619_-	hypothetical protein	NA	NA	NA	NA
WP_003229941.1\|2486615_2487194_-	YmfQ family protein	A0A2H4J717	uncultured_Caudovirales_phage	1.5e-14	33.8
WP_003229940.1\|2487177_2488224_-\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	8.3e-72	43.5
WP_004398572.1\|2488216_2488642_-	DUF2634 domain-containing protein	A0A0A8WJV8	Clostridium_phage	1.5e-11	36.4
WP_003229938.1\|2488654_2488918_-	DUF2577 family protein	NA	NA	NA	NA
WP_004398524.1\|2488914_2489895_-	hypothetical protein	H7BV96	unidentified_phage	2.1e-40	32.0
WP_004398548.1\|2489907_2490567_-	LysM peptidoglycan-binding domain-containing protein	A0A090DBR9	Clostridium_phage	4.8e-25	34.7
WP_003246092.1\|2490559_2495317_-	transglycosylase SLT domain-containing protein	A0A1L2JY60	Aeribacillus_phage	1.3e-44	47.2
WP_003229934.1\|2495319_2495457_-	hypothetical protein	NA	NA	NA	NA
WP_003229933.1\|2495498_2495948_-\|portal	phage portal protein	A0A0A7RTY8	Clostridium_phage	2.7e-11	41.1
WP_004398662.1\|2496093_2496273_+	type I toxin-antitoxin system toxin TxpA	NA	NA	NA	NA
WP_075058862.1\|2496652_2496742_+	type I toxin-antitoxin system toxin BsrH	NA	NA	NA	NA
WP_003229930.1\|2496995_2497439_-\|tail	phage tail tube protein	A0A0K2CNG3	Brevibacillus_phage	3.2e-25	45.4
WP_003229929.1\|2497441_2498842_-\|portal	phage portal protein	S5MNC1	Brevibacillus_phage	4.1e-74	39.1
WP_010886574.1\|2498842_2499034_-	hypothetical protein	NA	NA	NA	NA
WP_003229927.1\|2499030_2499468_-	hypothetical protein	NA	NA	NA	NA
WP_003246050.1\|2499480_2499984_-	HK97 gp10 family phage protein	A0A249XXA4	Clostridium_phage	8.3e-38	46.9
WP_003229925.1\|2499980_2500343_-	YqbH/XkdH family protein	A0A249XXE9	Clostridium_phage	6.9e-10	39.3
WP_004398566.1\|2500339_2500735_-	DUF3199 family protein	NA	NA	NA	NA
WP_003229923.1\|2500738_2501050_-	hypothetical protein	NA	NA	NA	NA
WP_003229922.1\|2501060_2501996_-\|portal	phage portal protein	A0A1B1P7E3	Bacillus_phage	8.6e-105	65.0
WP_003229921.1\|2502014_2502983_-\|portal	phage portal protein	A0A1B1P7E4	Bacillus_phage	7.4e-59	57.3
WP_003229920.1\|2503015_2503669_-	hypothetical protein	NA	NA	NA	NA
WP_004398748.1\|2503709_2504627_-	hypothetical protein	A0A1B1P7D7	Bacillus_phage	2.4e-51	39.1
WP_004398894.1\|2504623_2506156_-\|portal	phage portal protein	A0A1B1P7C8	Bacillus_phage	4.7e-148	51.9
WP_003229917.1\|2506159_2507455_-\|terminase	PBSX family phage terminase large subunit	A0A2P1JTW5	Anoxybacillus_phage	1.1e-155	63.4
WP_003229916.1\|2507447_2508167_-	hypothetical protein	A0A2P1JTW4	Anoxybacillus_phage	1.7e-55	55.9
WP_004398685.1\|2508234_2508699_-	hypothetical protein	NA	NA	NA	NA
WP_004398775.1\|2508842_2509298_-	hypothetical protein	A0A2H4J4R7	uncultured_Caudovirales_phage	2.4e-60	74.8
WP_003229913.1\|2509495_2510425_+	hypothetical protein	NA	NA	NA	NA
WP_003229912.1\|2510498_2510705_-	hypothetical protein	A0A2H4J4M6	uncultured_Caudovirales_phage	5.5e-20	71.6
WP_009967809.1\|2510786_2511215_-	RusA family crossover junction endodeoxyribonuclease	S6B1L9	Thermus_phage	5.6e-43	65.7
WP_003229910.1\|2511310_2511460_-	hypothetical protein	NA	NA	NA	NA
WP_075058863.1\|2511450_2512392_-	ATP-binding protein	A6XMI1	Bacillus_virus	8.0e-58	52.2
WP_010886575.1\|2512273_2512951_-	DNA-binding protein	A0A2H4J6G9	uncultured_Caudovirales_phage	1.1e-05	31.8
WP_003229907.1\|2513026_2513881_-	recombinase RecT	A0A2H4JCY8	uncultured_Caudovirales_phage	7.1e-122	79.0
WP_004398673.1\|2513883_2514843_-	YqaJ viral recombinase family protein	A0A2H4JA52	uncultured_Caudovirales_phage	2.2e-135	72.9
WP_003229905.1\|2514948_2515143_-	hypothetical protein	NA	NA	NA	NA
WP_119123069.1\|2515102_2515276_-	hypothetical protein	NA	NA	NA	NA
WP_003245994.1\|2515272_2515530_-	hypothetical protein	A0A2H4J4M9	uncultured_Caudovirales_phage	6.4e-10	42.2
WP_004398626.1\|2515526_2516096_-	helix-turn-helix transcriptional regulator	A0A2H4J884	uncultured_Caudovirales_phage	1.5e-64	61.0
WP_003229902.1\|2516169_2516310_-	hypothetical protein	NA	NA	NA	NA
WP_004398958.1\|2516339_2516570_-	helix-turn-helix transcriptional regulator	A8ATK0	Listeria_phage	1.1e-08	53.4
WP_004398704.1\|2516746_2517097_+	transcriptional regulator SknR	A0A2H4J6F9	uncultured_Caudovirales_phage	2.0e-06	30.6

DBSCAN-SWA_8

2650580 : 2703897

uncultured_Mediterranean_phage(12.5%)

protease,coat,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003229725.1\|2650580_2651726_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	3.4e-87	44.0
WP_003229723.1\|2651752_2652781_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_003222669.1\|2652810_2653011_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_003229718.1\|2653003_2654008_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.1e-07	30.8
WP_003229717.1\|2654018_2654624_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_003229715.1\|2654762_2655275_-	sporulation cell-cell signaling protein BofC	NA	NA	NA	NA
WP_003246197.1\|2655322_2656630_-	MFS transporter	NA	NA	NA	NA
WP_004398990.1\|2656700_2657726_-	inositol 2-dehydrogenase	NA	NA	NA	NA
WP_003246159.1\|2657963_2658611_+	serine/threonine protein kinase	A0A2R3ZQF2	Marseillevirus	5.4e-05	26.3
WP_003229707.1\|2658656_2658779_-	hypothetical protein	NA	NA	NA	NA
WP_003246047.1\|2658863_2659154_+	hypothetical protein	NA	NA	NA	NA
WP_004398683.1\|2659160_2659301_+	hypothetical protein	NA	NA	NA	NA
WP_004398698.1\|2659464_2660919_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_004398802.1\|2660959_2661682_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_003245996.1\|2661784_2662381_-	spore germination protein SgpA	NA	NA	NA	NA
WP_003229695.1\|2662528_2663692_-\|coat	spore coat assembly protein SafA	NA	NA	NA	NA
WP_003229691.1\|2663808_2664915_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_003229689.1\|2664901_2665771_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_003229687.1\|2665724_2667320_-	L-aspartate oxidase	NA	NA	NA	NA
WP_004398844.1\|2667422_2668610_+	cysteine desulfurase NifS	A0A141ZJV0	Faustovirus	8.6e-33	27.1
WP_004398582.1\|2668569_2669112_+	transcription repressor NadR	NA	NA	NA	NA
WP_004398512.1\|2669136_2669994_-	prephenate dehydratase	NA	NA	NA	NA
WP_003222630.1\|2670010_2670454_-	transcriptional regulator ThrR	NA	NA	NA	NA
WP_003246161.1\|2670514_2671801_-	GTPase ObgE	NA	NA	NA	NA
WP_004399131.1\|2671834_2672413_-	sporulation initiation phosphotransferase Sop0B	NA	NA	NA	NA
WP_003229671.1\|2672490_2672613_+	hypothetical protein	NA	NA	NA	NA
WP_003222623.1\|2672733_2673018_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_003229669.1\|2673030_2673369_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_003229668.1\|2673371_2673680_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_004398649.1\|2673826_2674693_-	stage IV sporulation protein SpoIVFB	NA	NA	NA	NA
WP_004398684.1\|2674685_2675480_-	stage IV sporulation protein SpoIVFA	NA	NA	NA	NA
WP_004398624.1\|2675629_2676436_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_004398901.1\|2676437_2677118_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_004398811.1\|2677170_2677689_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_009967915.1\|2677685_2678558_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_003229650.1\|2678588_2679602_-	rod shape-determining protein MreB	NA	NA	NA	NA
WP_003246034.1\|2679693_2680389_-	JAB domain-containing protein	NA	NA	NA	NA
WP_004398496.1\|2680425_2680995_-	septum formation protein Maf	NA	NA	NA	NA
WP_004398782.1\|2681147_2682146_-	stage II sporulation protein SpoIIB	NA	NA	NA	NA
WP_010886586.1\|2682279_2683026_-	prepilin peptidase	NA	NA	NA	NA
WP_003229640.1\|2683165_2684458_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_004398606.1\|2684517_2687160_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	3.7e-161	42.6
WP_003222590.1\|2687607_2687799_+	hypothetical protein	NA	NA	NA	NA
WP_004399056.1\|2687817_2688843_-\|coat	spore coat protein CotN	NA	NA	NA	NA
WP_003246083.1\|2688875_2690603_-\|coat	spore coat morphogenetic protein SpoVID	NA	NA	NA	NA
WP_004398699.1\|2690733_2692026_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_003229631.1\|2692055_2693030_-	porphobilinogen synthase	NA	NA	NA	NA
WP_003229629.1\|2693026_2693815_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_010886587.1\|2693804_2694749_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_003222575.1\|2694781_2695612_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_004399038.1\|2695619_2696987_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_003229624.1\|2697216_2697714_+	hypothetical protein	NA	NA	NA	NA
WP_003229621.1\|2697735_2698323_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_003229618.1\|2698319_2700644_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	3.4e-182	43.7
WP_004398923.1\|2700824_2702483_-\|protease	ATP-dependent protease LonB	A0A1V0SHJ7	Hokovirus	8.1e-05	33.7
WP_003229613.1\|2702634_2703897_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.3e-148	64.9

DBSCAN-SWA_9

3277659 : 3288856

Organic_Lake_phycodnavirus(50.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003228374.1\|3277659_3278340_-\|holin	choline ABC transporter permease OpuBD	NA	NA	NA	NA
WP_003228372.1\|3278356_3279277_-	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003228370.1\|3279288_3279942_-\|holin	choline ABC transporter permease OpuBB	NA	NA	NA	NA
WP_003242811.1\|3279958_3281104_-\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.0e-15	32.7
WP_003243347.1\|3281387_3281921_+	GbsR/MarR family transcriptional regulator	NA	NA	NA	NA
WP_009968174.1\|3282142_3282619_+	sporulation-delaying system protein SdpA	NA	NA	NA	NA
WP_003228363.1\|3282615_3283587_+	sporulation-delaying protein SdpB	NA	NA	NA	NA
WP_003243360.1\|3283629_3284241_+	sporulation delaying protein SdpC	NA	NA	NA	NA
WP_003228357.1\|3284287_3284911_-	immunity protein SdpI	NA	NA	NA	NA
WP_003243541.1\|3284907_3285180_-	sporulation delaying system autorepressor SdpR	NA	NA	NA	NA
WP_003244403.1\|3285399_3286089_-\|holin	glycine betaine/carnitine/choline/choline sulfate ABC transporter permease OpuCD	NA	NA	NA	NA
WP_003228350.1\|3286106_3287018_-	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003228349.1\|3287037_3287691_-\|holin	glycine betaine/carnitine/choline/choline sulfate ABC transporter permease OpuCB	NA	NA	NA	NA
WP_003243370.1\|3287713_3288856_-\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.2e-12	29.3

DBSCAN-SWA_10

3651504 : 3728117

Bacillus_phage(26.67%)

protease,coat,tRNA,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003227570.1\|3651504_3653175_-\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_003243604.1\|3653171_3653600_-	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_003222002.1\|3653912_3654044_+\|bacteriocin	subtilosin A family bacteriocin	NA	NA	NA	NA
WP_010886632.1\|3654000_3654153_+\|bacteriocin	bacteriocin-like protein SboX	NA	NA	NA	NA
WP_003242599.1\|3654177_3655524_+	subtilosin maturase AlbA	NA	NA	NA	NA
WP_003222006.1\|3655536_3655698_+\|bacteriocin	antilisterial bacteriocin subtilosin biosynthesis protein AlbB	NA	NA	NA	NA
WP_003227564.1\|3655694_3656414_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.3e-19	27.2
WP_003243158.1\|3656406_3657717_+\|bacteriocin	antilisterial bacteriocin subtilosin biosynthesis protein AlbD	NA	NA	NA	NA
WP_010886633.1\|3657706_3658867_+	insulinase family protein	NA	NA	NA	NA
WP_003242974.1\|3658871_3660152_+	insulinase family protein	NA	NA	NA	NA
WP_003243391.1\|3660148_3660850_+\|bacteriocin	antilisterial bacteriocin subtilosin biosynthesis protein AlbG	NA	NA	NA	NA
WP_003244415.1\|3660855_3662232_-	YncE family protein	NA	NA	NA	NA
WP_003227552.1\|3662270_3663626_-	YncE family protein	NA	NA	NA	NA
WP_009968328.1\|3663622_3663853_-	hypothetical protein	NA	NA	NA	NA
WP_003227549.1\|3663855_3665001_+	response regulator aspartate phosphatase RapF	A0A1P8CWN8	Bacillus_phage	1.7e-78	43.5
WP_009968329.1\|3664984_3665104_+	phosphatase RapF inhibitor PhrF	NA	NA	NA	NA
WP_003227547.1\|3665202_3665676_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_003227545.1\|3665707_3666580_-	agmatinase	NA	NA	NA	NA
WP_003227543.1\|3666640_3667471_-	spermidine synthase	NA	NA	NA	NA
WP_003227540.1\|3667672_3669748_+	penicillin-binding protein	NA	NA	NA	NA
WP_003244446.1\|3670040_3670559_-	hypothetical protein	NA	NA	NA	NA
WP_003243167.1\|3670572_3671232_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_003222038.1\|3671340_3671529_+	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_003242889.1\|3671571_3671991_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_003243399.1\|3672110_3674027_-\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	6.2e-142	43.2
WP_003243441.1\|3674871_3676272_-	MFS transporter	NA	NA	NA	NA
WP_003243988.1\|3676271_3676742_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_003227524.1\|3676853_3677354_-	YwgA family protein	NA	NA	NA	NA
WP_003243873.1\|3677389_3678691_-	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	4.2e-25	28.9
WP_003222050.1\|3678852_3679077_-	DUF1450 domain-containing protein	NA	NA	NA	NA
WP_003243464.1\|3679291_3680068_+	prespore-specific transcription regulator RsfA	A0A1D6X8E5	Bacillus_phage	7.6e-06	50.0
WP_003242581.1\|3680211_3681102_-	DMT family transporter	NA	NA	NA	NA
WP_003227511.1\|3681269_3682115_-	octanoyl-[GcvH]:protein N-octanoyltransferase	NA	NA	NA	NA
WP_003243173.1\|3682163_3683063_-	cysJI operon transcriptional regulator CysL	A0A2H4J8I9	uncultured_Caudovirales_phage	3.6e-07	42.5
WP_003243393.1\|3683209_3684181_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_003242896.1\|3684450_3685215_+	heme-dependent peroxidase	NA	NA	NA	NA
WP_003244095.1\|3685347_3686127_+	NADPH-dependent reductase BacG	NA	NA	NA	NA
WP_003242568.1\|3686141_3687341_-	transaminase BacF	NA	NA	NA	NA
WP_003244502.1\|3687341_3688526_-	bacilysin exporter BacE	NA	NA	NA	NA
WP_003242921.1\|3688522_3689941_-	alanine--anticapsin ligase	NA	NA	NA	NA
WP_003243359.1\|3689959_3690721_-	dihydroanticapsin 7-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	2.8e-21	30.9
WP_003244300.1\|3690723_3691431_-	3-((4R)-4-hydroxycyclohexa-1, 5-dien-1-yl)-2-oxopropanoate isomerase	NA	NA	NA	NA
WP_009968341.1\|3691420_3692035_-	prephenate decarboxylase	NA	NA	NA	NA
WP_003242790.1\|3692186_3693425_-	MFS transporter	NA	NA	NA	NA
WP_003244348.1\|3693634_3695047_-	amino acid permease	NA	NA	NA	NA
WP_003227487.1\|3695046_3696747_-	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_003243454.1\|3696820_3698368_-	L-glutamate gamma-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_003227482.1\|3698594_3699869_-	glutamate dehydrogenase	NA	NA	NA	NA
WP_003242493.1\|3700045_3700510_-	biofilm-surface layer protein BslB	NA	NA	NA	NA
WP_003242881.1\|3700833_3701289_-\|coat	spore coat polysaccharide biosynthesis protein SpsL	NA	NA	NA	NA
WP_003242585.1\|3701281_3702133_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	4.1e-37	38.5
WP_003244201.1\|3702146_3703094_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	4.4e-72	43.8
WP_003243368.1\|3703093_3703834_-	NTP transferase domain-containing protein	I7I009	Enterobacteria_phage	2.6e-48	41.9
WP_003244190.1\|3703858_3704878_-\|coat	spore coat polysaccharide biosynthesis protein SpsG	NA	NA	NA	NA
WP_003243421.1\|3704880_3705603_-\|coat	spore coat polysaccharide biosynthesis protein SpsF	NA	NA	NA	NA
WP_003243135.1\|3705595_3706717_-\|coat	spore coat biosynthesis protein SpsE	NA	NA	NA	NA
WP_003243179.1\|3706716_3707586_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003243878.1\|3707586_3708756_-	DegT/DnrJ/EryC1/StrS aminotransferase family protein	A0A1D8KU11	Synechococcus_phage	5.5e-16	26.6
WP_003243510.1\|3708776_3710201_-	CDP-glycerol glycerophosphotransferase family protein	NA	NA	NA	NA
WP_003244383.1\|3710205_3710976_-\|coat	spore coat dTDP-glycosyltransferase SpsA	A0A0F7L2F7	uncultured_marine_virus	3.4e-06	28.6
WP_003227448.1\|3711295_3711841_+\|coat	spore coat protein GerQ	NA	NA	NA	NA
WP_003227446.1\|3711884_3712256_-	DUF423 domain-containing protein	NA	NA	NA	NA
WP_010886635.1\|3712317_3713640_-	purine permease	NA	NA	NA	NA
WP_003243806.1\|3713659_3713977_-	YwdI family protein	NA	NA	NA	NA
WP_023592815.1\|3714144_3715515_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_003242965.1\|3715539_3716217_-	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	8.3e-49	46.1
WP_003242519.1\|3716230_3717037_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_009968358.1\|3717126_3717660_-	hypothetical protein	NA	NA	NA	NA
WP_003227434.1\|3717707_3718343_-	hypothetical protein	NA	NA	NA	NA
WP_003227432.1\|3718335_3718674_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_003242645.1\|3718817_3719633_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_003243437.1\|3719722_3719971_-	hypothetical protein	NA	NA	NA	NA
WP_023592816.1\|3720064_3721504_-	sucrose-6-phosphate hydrolase	S6ATV4	Bacillus_phage	7.0e-21	26.3
WP_003222147.1\|3721500_3722886_-	PTS system sucrose transporter subunit IIBC	NA	NA	NA	NA
WP_003222150.1\|3723186_3723957_+	formate/nitrite transporter family protein	NA	NA	NA	NA
WP_003222152.1\|3723995_3724826_-	sac operon transcriptional antiterminator SacT	NA	NA	NA	NA
WP_003222155.1\|3724865_3725168_-	hypothetical protein	NA	NA	NA	NA
WP_003227419.1\|3725696_3728117_+\|protease	serine protease Vpr	A0A217EQY2	Bacillus_phage	6.9e-21	36.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022898

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection