CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_022738	Pseudomonas sp. VLB120, complete sequence	1 crisprs	DEDDh,WYL,csa3,cas3,DinG,TnsE_C	0	0	6	0
NC_022739	Pseudomonas sp. VLB120 plasmid pSTY, complete sequence	1 crisprs	NA	0	1	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_022738_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022738_1

4737166-4737263

Orphan

Consensus_repeat	Method
GCGAGCCTTGCTCGCGATGCGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022738_1

>merge|NC_022738|1|4737166-4737263|CRISPRCasFinder
GCGAGCCTTGCTCGCGATGCGCTACGAGTCGCGCGCGCCCGTCACTGCCGTTACTGGCCCGAAACAAACGTAGGAGCGAGCCTTGCTCGCGATGCGCC

>NC_022738|1|1|4737166-4737263|CRISPRCasFinder
GCGAGCCTTGCTCGCGATGCGCT	ACGAGTCGCGCGCGCCCGTCACTGCCGTTACTGGCCCGAAACAAACGTAGGA
GCGAGCCTTGCTCGCGATGCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_022738.1\|WP_023382380.1\|4747548_4747692_-\|hypothetical-protein	unknown	unknown	unknown
NC_022738.1\|WP_023382376.1\|4742212_4742728_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|171561
NC_022738.1\|WP_023382377.1\|4742714_4743665_+\|DUF4880-domain-containing-protein	unknown	unknown	gnl\|CDD\|236622
NC_022738.1\|WP_023382373.1\|4737859_4740262_-\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|225803
NC_022738.1\|WP_023382366.1\|4728807_4729905_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|182881
NC_022738.1\|WP_023382378.1\|4743761_4746233_+\|TonB-dependent-siderophore-receptor	unknown	unknown	gnl\|CDD\|227114
NC_022738.1\|WP_023382368.1\|4731808_4732627_-\|polyphosphate-kinase-2	unknown	unknown	gnl\|CDD\|213852
NC_022738.1\|WP_027907463.1\|4726183_4727284_-\|HlyD-family-secretion-protein	unknown	unknown	gnl\|CDD\|224482
NC_022738.1\|WP_023382381.1\|4747821_4749036_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341031
NC_022738.1\|WP_023382365.1\|4727280_4728795_-\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|273830
NC_022738.1\|WP_023382372.1\|4735594_4737025_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143428
NC_022738.1\|WP_023382363.1\|4725174_4726194_-\|DUF2955-domain-containing-protein	unknown	unknown	gnl\|CDD\|371403
NC_022738.1\|WP_023382369.1\|4732732_4733353_-\|hydrolase	unknown	unknown	gnl\|CDD\|238494
NC_022738.1\|WP_023382374.1\|4740318_4741377_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	unknown	unknown	gnl\|CDD\|185333
NC_022738.1\|WP_023382371.1\|4734081_4735581_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|224374
NC_022738.1\|WP_023382379.1\|4746303_4747464_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341030
NC_022738.1\|WP_023382370.1\|4733595_4733985_+\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|379209
NC_022738.1\|WP_023382375.1\|4741412_4742039_-\|DNA-3-methyladenine-glycosylase-2-family-protein	unknown	unknown	gnl\|CDD\|223200
NC_022738.1\|WP_023382367.1\|4729987_4731709_-\|cation:proton-antiporter	unknown	unknown	gnl\|CDD\|235131
NC_022738.1\|WP_023382382.1\|4749226_4750150_+\|FecR-domain-containing-protein	unknown	unknown	gnl\|CDD\|226235

Protein	Function_ID	Function_description	E-value
NC_022738.1\|WP_023382376.1\|4742212_4742728_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|171561	PRK12528, PRK12528, RNA polymerase sigma factor; Provisional.	6.04511e-55
NC_022738.1\|WP_023382377.1\|4742714_4743665_+\|DUF4880-domain-containing-protein	gnl\|CDD\|236622	PRK09774, PRK09774, fec operon regulator FecR; Reviewed.	5.23567e-67
NC_022738.1\|WP_023382373.1\|4737859_4740262_-\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|225803	COG3264, COG3264, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	4.82355e-168
NC_022738.1\|WP_023382366.1\|4728807_4729905_-\|AI-2E-family-transporter	gnl\|CDD\|182881	PRK10983, PRK10983, AI-2E family transporter YdiK.	1.64227e-36
NC_022738.1\|WP_023382378.1\|4743761_4746233_+\|TonB-dependent-siderophore-receptor	gnl\|CDD\|227114	COG4773, FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism].	0
NC_022738.1\|WP_023382368.1\|4731808_4732627_-\|polyphosphate-kinase-2	gnl\|CDD\|213852	TIGR03707, PPK2_P_aer, polyphosphate kinase 2, PA0141 family. Members of this protein family are designated polyphosphate kinase 2 (PPK2) after the characterized protein in Pseudomonas aeruginosa. This family comprises one of three well-separated clades in the larger family described by pfam03976. PA0141 from this family has been shown capable of operating in reverse, with GDP preferred (over ADP) as a substrate, producing GTP (or ATP) by transfer of a phosphate residue from polyphosphate. Most species with a member of this family also encode a polyphosphate kinase 1 (PPK1). [Central intermediary metabolism, Phosphorus compounds].	1.08826e-140
NC_022738.1\|WP_027907463.1\|4726183_4727284_-\|HlyD-family-secretion-protein	gnl\|CDD\|224482	COG1566, EmrA, Multidrug resistance efflux pump [Defense mechanisms].	3.12066e-69
NC_022738.1\|WP_023382381.1\|4747821_4749036_-\|MFS-transporter	gnl\|CDD\|341031	cd17478, MFS_FsR, Fosmidomycin resistance protein of the Major Facilitator Superfamily of transporters. Fosmidomycin resistance protein (FsR) confers resistance against fosmidomycin. It shows sequence similarity with the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. This FsR family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.23599e-100
NC_022738.1\|WP_023382365.1\|4727280_4728795_-\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|273830	TIGR01845, Outer_membrane_protein_OprM, efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. Members of this model comprise a subfamily of the Outer Membrane Factor (TCDB 1.B.17) porins. OMF proteins operate in conjunction with a primary transporter of the RND, MFS, ABC, or PET systems, and a MFP (membrane fusion protein) to tranport substrates across membranes. The complex thus formed allows transport (export) of various solutes (heavy metal cations; drugs, oligosaccharides, proteins, etc.) across the two envelopes of the Gram-negative bacterial cell envelope in a single energy-coupled step. Current data suggest that the OMF (and not the MFP) is largely responsible for the formation of both the trans-outer membrane and trans-periplasmic channels. The roles played by the MFP have yet to be determined. [Cellular processes, Detoxification, Transport and binding proteins, Porins].	6.1933e-72
NC_022738.1\|WP_023382372.1\|4735594_4737025_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143428	cd07110, ALDH_F10_BADH, Arabidopsis betaine aldehyde dehydrogenase 1 and 2, ALDH family 10A8 and 10A9-like. Present in this CD are the Arabidopsis betaine aldehyde dehydrogenase (BADH) 1 (chloroplast) and 2 (mitochondria), also known as, aldehyde dehydrogenase family 10 member A8 and aldehyde dehydrogenase family 10 member A9, respectively, and are putative dehydration- and salt-inducible BADHs (EC 1.2.1.8) that catalyze the oxidation of betaine aldehyde to the compatible solute glycine betaine.	0
NC_022738.1\|WP_023382363.1\|4725174_4726194_-\|DUF2955-domain-containing-protein	gnl\|CDD\|371403	pfam11168, DUF2955, Protein of unknown function (DUF2955). Some members in this family of proteins with unknown function annotate the proteins as membrane protein. However, this cannot be confirmed.	2.63858e-25
NC_022738.1\|WP_023382369.1\|4732732_4733353_-\|hydrolase	gnl\|CDD\|238494	cd01012, YcaC_related, YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. Multimerisation interface seems not to be conserved in all members.	2.81726e-71
NC_022738.1\|WP_023382374.1\|4740318_4741377_-\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	gnl\|CDD\|185333	PRK15435, PRK15435, bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada.	1.34703e-144
NC_022738.1\|WP_023382371.1\|4734081_4735581_+\|cytosine-permease	gnl\|CDD\|224374	COG1457, CodB, Purine-cytosine permease and related proteins [Nucleotide transport and metabolism].	4.58788e-77
NC_022738.1\|WP_023382379.1\|4746303_4747464_-\|MFS-transporter	gnl\|CDD\|341030	cd17477, MFS_YcaD_like, YcaD and similar transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MFS-type transporter YcaD, Bacillus subtilis MFS-type transporter YfkF, and similar proteins. They are uncharacterized transporters belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.15731e-73
NC_022738.1\|WP_023382370.1\|4733595_4733985_+\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|379209	pfam13474, SnoaL_3, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	9.0002e-16
NC_022738.1\|WP_023382375.1\|4741412_4742039_-\|DNA-3-methyladenine-glycosylase-2-family-protein	gnl\|CDD\|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	3.42906e-55
NC_022738.1\|WP_023382367.1\|4729987_4731709_-\|cation:proton-antiporter	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	1.62705e-158
NC_022738.1\|WP_023382382.1\|4749226_4750150_+\|FecR-domain-containing-protein	gnl\|CDD\|226235	COG3712, FecR, periplasmic ferric-dicitrate binding protein FecR, regulates iron transport through sigma-19 [Inorganic ion transport and metabolism, Signal transduction mechanisms].	3.01818e-49

>NC_022738.1|WP_023382372.1|4735594_4737025_+|aldehyde-dehydrogenase-family-protein
MTHSHYIAGRWVEGQGSDCITVNDPSLGQPFAELRAASVAQVDQAVAAARQALTTWKAVSAAARAAFLRGFAEQLGQRREELIGLQMRNNGKPRHEAEIDLDDAVATFAYYADLAEQLPAKNRDVPLAAPGFTARTRLEPVGVVGLIVPWNFPLVTSAWKLAPALAAGCTVVLKPSEVTPLIEQAYGQIADTLGLPAGVLNIVNGKAETGAALSGHNGLDKLSFTGSNSVGSQVMRSASAQCRPVTLELGGKSAIVVFDDCDVDQAVDWIVAGITWNAGQMCSATSRLLVQDGIADALLPRLQQALDKLRVGNPLIEEVDMGPLTSQAQWLKVASYFATAREEGLQCLAGGKALDRDGWFVSPTLYAEVPKDSRLWTEEIFGPVLCARRFSTEAQAIAEANDSRFGLVATVCSADLERAERVADALEVGHVWINSVQAVFVETSWGGTKGSGIGRELGPWGLSGYLSVKHVTRCLG
>NC_022738.1|WP_023382371.1|4734081_4735581_+|cytosine-permease
MSHSTGIETNGVEQIPDDQRDASPLDLFRLIFGGANTFATAVLGSFPVLFGLSFQAGVWAIVLGVGVGSLILAPMGLFGALNGTNNAVSSGAHFGVHGRIVGSFLSLLTAVAFFSLSVWSSGDALVGGAKRLAGLPETDLTLGLAYGLFAVLVLVVCIFGFRFMLWVNKIAVWASSLLFLLGIFAFAGPFDADFAGSVNLGQPGFWAAFVGAAILAMSNPVSFGAFLGDWSRYIPRETPKARIMLAVIAAQVATLIPFLFGLCTATLVASQAPDYIAANNYVGGLLAISPSWFFLPVCLIAVIGGMSTGTTALYGTGLDMSSVFPRLLSRAGATLLIGVAAIAFIFIGRFTFNLVQSVSTFAVLIITCTSPWMVIMILGLITRRGFYHADDLQVFTRGQRGGHYWFLHGWNWRGMGAWIPSAAVGLCFVNLPGQFVGPLGDLAGGIDLSLPVTLGLAGVLYLILLNVFPEPAGVYGPNGPRWVPSKRTPHLPVTTAEMA
>NC_022738.1|WP_023382370.1|4733595_4733985_+|nuclear-transport-factor-2-family-protein
MDQTLQVRQAAADLVEAFASNDTARYFACFSEDATFLFHTLPQPLLSRRAYEDLWAQWQAEGFAVLACRSSNVHVSLQGDVAVFMHDVATHIRMADQEHQLAERETIVFRRQGERWLACHEHLSVVTAA
>NC_022738.1|WP_023382369.1|4732732_4733353_-|hydrolase
MTFQYKRLDKNDAAVLLVDHQAGLLSLVRDIDPDRFKNNVLALSDLAKYFKLPTILTTSFETGPNGPLVPELKAQFPDAPYIARPGNINAWDNEDFVKAVKATGKKQLIIAGVVTEVCVAFPALSALEEGFEVFVVTDASGTFNELTRDSAWRRMEAAGAQLMTWFGVACELHRDWRNDIEGLGTLFSNHIPDYRNLMTSYNKLAK
>NC_022738.1|WP_023382368.1|4731808_4732627_-|polyphosphate-kinase-2
MSKSAKKKATQSSDEKLSGKDYEKALKSLHVELVKLQEWVVAKGLKVCIVFEGRDGAGKGGTIKAITERVSPRVFRVVALPAPTEREKTQMYVQRYLGHLPAAGEVVIFDRSWYNRAGVERVMGFCTEEQANKFLTVVPLFEKMMVESGIILIKYWLEVSAEEQTRRLQDRINDGRKLWKLSPMDLKSYSRWDDYTHARDEMFAASDSSWAPWFMAHSNDKRRARLNIISHLLSRIEYKDVTREEIVKLPKRGKIGKYKSVDYPFKVVPERF
>NC_022738.1|WP_023382367.1|4729987_4731709_-|cation:proton-antiporter
MPHDGSLLQATVVFLLAVVLLVPLAQRLKLGAVPGYLLAGILIGPSMLGLINHPENVSRLSEMGVVMLLFVIGLELSPRRLWTMRRSLFGVGSLQVALTAVVLGLLAYLVFGQPRAAAIVLGLGLALSSTAFGLQVLAERRELGKPQGRLAVSILLFQDIAAIPLIAVVPLLGTGISPPEEGSWPLLAVALGVGLVIVTGRYLLQPVFRWTVGSGLHELSTATALLVVLGTAWVMEHVGVSMALGAFLAGVVMADSPFRHELESQVEPLKGLLLGLFFVGVGMTADLRLLLSMPVQVLGLTVLLVGVKLPLLFMLGRTAGGLERAQALCLAVVLASGGEFAFVVFKLALEHRVLEQQVHDLLVLAITLSMAVVPLVMMALARQLRDDATVAAAAAALPEVDETPQVVVAGLGRMGGAIVRMLHGEGVRLVALDTSIESVSRSSEPDGPLVFFGDPSRSEILRAARVDQAKLVIVATDDPQANLKAADVLAHLYPQTPVIAAARDSQEALRLLAMGVDPVRETFHSSLEMARRALITLGYSEEQASAWVQRYQRQEARRLLDQQHGKGDFPGAR
>NC_022738.1|WP_023382366.1|4728807_4729905_-|AI-2E-family-transporter
MQSGFKLDSALSRGLLDVLIKAGLVAALVIFAFQVFEPFLELMLWAVILAVTLYPLYSRIKRRIGLKNGYVATLVVLLVLVVLLVPIYLVVVSIGESVHSLVALLKEGGWSVPAPPESVAGWPLIGPRLYAFWQSASESLAPVMNNLMPHLKGVGLSMLGAAASAGGAFLLFIGAVIISGVIMAFGERGEIAAQRIAMRVSGEERGKPLAKLCTATIRAVAQGVIGIAFIQMLLIGVGFVVKGVPGAGMLAIVVLMLGIAQAPATLVTVPVIIYVFNVEGFTAATIVFAVYTFVAGLADNVLKPLLLGRGVDVPMPVVLIGALGGMVVKGIIGLFIGPVILGVAYVLFWQWVALQVPEQPVPPAA
>NC_022738.1|WP_023382365.1|4727280_4728795_-|efflux-transporter-outer-membrane-subunit
MPKRCHGLILLLVLTGCSQVGPDFAAPQDRWLQGWSTPLLEQAGRTAPTPDLSRWWAVFADPTLDALIAEADAQNTNLRVAGLRIVEARAQLAIVQTGRYPQLQQLRAQSLYLKQDQSGTPTARDSVFWQSSLGFDIAWEVDFWGRFSRAIESADAAYFASQANYADAMVLLRAQVADTYFGLRTAEARLAIAQENAWRQARSLEITERLFRHGENDELDWQQARTQYLATQATIPEFQNQVNALRNVLCSLIGRPPGPLPELEARHGQLPLPDRAVLQDVPANLLQRRPDIRAAEQAVAAQSALVGVAEADLYPSLSLLGSIGWSFVTANHVPDTFDLAAGPSLIWNPFDYDRRKNAVRVEDARLQQLIERYHQNVRDAAREADDAASGLVRSLESAGIRQQASQAAQRSLSLASSQYREGFADFQRVLDAQQLLLQQQDGYLVSRGNAVSSLVSLYKALGGGWEQVGEPIPPATRQQMQQRTDWGTLLDGPAPEHQETGTRR
>NC_022738.1|WP_027907463.1|4726183_4727284_-|HlyD-family-secretion-protein
MSDAQGTPPTPAAPDRGMRWVLLLIVVSLVWYLLADRFTPYTQQARLQAYVVPVSAEVAGQIRRVAVGNNQEVRRGDVLFELDPEQYRIALARAEADLDTMRRQIGAHTAGIDSAQAALVAAQANERKARQDAERLKRLIDEDPGTVSVRRLEGAQATRDQAISQVAAARAEVERAREQQGGAEADNAQLRSAAANVQKARLDLARTVVRAEANGLITDLRTDVGHYVAAGSPMMTLIAIHDLWISADMTENNLGYLQSGTPVLVVLDALPGKVLRGRVRSIGRGVSVGQSTPPGSLPTVQNSREWLRSAQRFPVIVELERDQLQSAAGLRVGGQAEVMALPREGNPLNLLARVFMWLMSWMSYAY
>NC_022738.1|WP_023382363.1|4725174_4726194_-|DUF2955-domain-containing-protein
MPIELRRLRALRLAWGTALCLAVSFGLGLPVPILAPVFAVLLLAMRSQPLPLRAAPLLALLVLLSCGSGLLLIPLLRHAPVSGVLVVGTGVYLVLRYALLGGNGLLANLLVIGLTMIAAAGTSDFTLALSVVEAMAKGMLLATLGCALAHLLFPEPADAPVPSPPARLNDNEVGWVALRATLIVMPAFLLALIAPDTFMPLIMKSVSLGQQAGETHARHASRELIGSTLLAGALAILLWGALGLFVHLWMFFLWGLLFCLWQARRLYQAVMTQQTPAFWISCLTTFLILLGQSVQDSAAGQDVYRAFAVRMALFVAVSLYASAMLIWIDRRRARQVVTP
>NC_022738.1|WP_023382373.1|4737859_4740262_-|mechanosensitive-ion-channel-family-protein
MRRVSLARYCLGVIALMLALATPAWSAPATPVSNLAGGELPVLAEDASLDQLNERLDFIRQGVTSNANDDLLSQLRQAAIQVQRQADVLSSQRATDVQKLDDQLKVIGPAQPDEPQSLAQQRKQLEAEHKAVLAEQEQATKLTQSARDLSTQIVNLRRSQFNSQVTSRAASPLSPAFWQTLIRPTEEDVLRLRDLRSEAADAVASAFSAEHRWLFITSLVAAILVWTLVRRVLERLLADAMVRWLPEGRLRRSALALSVSLATLGTIAGSVSLLRWGLESSAELGADLASLTNHILTLVVFSAFISGLGRAMLMLQRPSWRLPPIHDEVASALGWFPKLLALALMVMLTQERINSVIGSSLALTVATNGLTALVVALIFSAALLRYRRTLRKHELERPTGLAGLIPFVIVVWVGLILLALLAGYLTLAYFLTAKLLWISVVATCAYLLTTFLGDLCETLLSPRQPGGLALASALGLAPRHQAQASTILAGIGRTALLFLALLLALMPSGTSPGELLLSLGDWDGTGGKVLGNLNIVPQDILLALVMFFGGLFGIRVVKRWLSERLLPETDMDAGMRASLVTLVGYLGFLFLAMLVMSTLRINLTSLTWVVSALSVGIGFGLQQIVQNFISGLILLTERPVKVGDWVSLAGVEGDIRRINVRATEIQMSDRSTVIVPNSQFISQNVRNVTMGNALGVVGISLTLPLETDANRVRELLLAAYREHESILDAPASSVTFKDLTASGMVIAVSGYVAGPRQVSGTRSDLLFTILGRLRDEGISLSSPQSMVLVQEGARPADEQA
>NC_022738.1|WP_023382374.1|4740318_4741377_-|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada
MSLYITDAQRWQAVQSRDSAAADDFVYAVRTTQVYCRPGCKSRMAKRENVVFFDDAAAAQAAGYRPCRRCGVDHDAAAARRTQLIARACRLIEAGDSAANLDQLAAQLAVSPFHLHRLFKAETGLTPKAYAAAFRARALREQLGDEQRSVTEAIYEAGYNSNSRFYETAGQRLGMLPKAYKAGGAGATIRFALGECSLGAILVAQSEKGICAILLGDDPEALLHELQDQFPKASLIGGDSEFERLVAEVVGFVEAPSIGLALPLDVQGTAFQERVWQALREVPAGSRVSYTDIAERIGAPKAMRAVAQACAANRIAVAIPCHRVVRRDGDVSGYRWGVERKVQLLTRETALS
>NC_022738.1|WP_023382375.1|4741412_4742039_-|DNA-3-methyladenine-glycosylase-2-family-protein
MILADLSPEAFSEATDYLASLDPDWARHIAATGPCLHQATPEREPYEALVRAIAYQQLHARAAEAILARLLALFPDVAFPEPSQLLATTPEAMRACGFSASKLATIHGIAQARMDGVIPDRQEALSLTDDALIERLVALRGVGRWTVEMLLIYCLERSDILPVDDFGVREGYRRLKGWDKAPTPAQLRSLGGAWSPYRTVAAWYLWRA
>NC_022738.1|WP_023382376.1|4742212_4742728_+|sigma-70-family-RNA-polymerase-sigma-factor
MQMNDTLKPTEVALLYQSHHAWLRGWLRSRVGCHEHAADLAQDTFVRLLRARQVSPLKEPRAYLSSIARGLMIDQFRRRALERAYLESLATLPEAEIPSEEHRLVILDTLERLDRALQQLKPRARQAFLLAQLDGLSIAQIALRLDVSRATVERDLAKALGVCYRLRYADL
>NC_022738.1|WP_023382377.1|4742714_4743665_+|DUF4880-domain-containing-protein
MPTSDSTPNQAQVDQAIDWLVRLRFDTPSPRTRQRFQQWLASHPHNAHAWERVSHLSDELAGLPSELSRRTLEGSQRISRRDHLKLLAVLAVGSSLGWAAREPLGLPALLADTHTSTGERRQLLGSDGSRIQLNTASAIDLRYSDTQRELKLVHGEVSLACNANDNRPFLLGTRIGALSTRDGHLLLRENDQGVLLAVRSGEVTMFPDSSAPRRVQPGEVLQVASAASYAPATLYADPWGWTDGVLSVQQMPLGEFVAELSRYRPGLLRCAPEVAGLKVSGTYQLADTERILLLLARSLPVRVVYRTRYWVSIGAV
>NC_022738.1|WP_023382378.1|4743761_4746233_+|TonB-dependent-siderophore-receptor
MIHPCSPRNDRLRHAVRAAVFGLGLGAGLAASVTALAAPASQRQQLDWRIAAGPLAPALDQLARQGGLNLSFDANSLQGKTTQGVQGRHDAAQALSILLQGSDVQVQQEGDNSFLLIPAMDVGDALELGATSISSNRLGETTENTGSYTTGAVTIGKIPQSLRHTPQSVSVVTRQRIDDQNITNLTNLLEQTPGVVVNYTDSERVQYFSRGFLIDAIQYDGATVVQSSGGGSFIQSDSAFIDRAEVLRGATGMLRGAGNPSGTVNLVRKRPTHEFQASGTATLGSWNAQRYVADISGPLTDTGNVRGRVIAVHDDRDLFQDSRMERKEAFGGSLAFDLDDSTTLTTGFEWTKLDATGAWGNLPADYDGSPLPLGRSTYLGADWNRWDRSNLNTYAELEHHFDNDWTLKLMALRSHFELDDNGFKQTYMTRAPARLNPTNNPYLMQYQVTEGDGGESLQNNLSATLNGPFDLFGRTHELMLGVERIRNDSYASGTNRVVYSDVVDIRDWDPRTSLDEPTITDIPHPVRTRTTQQAVHATWRISLADPLTAIIGARANWYDYEQENNAGASGKFSVDEKIVPYAALIYDLNDNFSVYASYTEIFNPQTVVDKNNKVLDPIVGEAYETGIKGEFYDGRLNTSLAFFRINQVGTPIDDTSVPIGCNGSTGYCKIASGKSRSEGIDLEISGEVLPGWQVTGGYTYNTTEYVKNTAQTNGDAIRTTDPEHMLRVFTSYRLPGTLDAWTIGAGVQAQSDIYSQSGSAKATQAGYAVYNGLLKYRINDNYSVQLNANNLFDKHYYRQIGTTATGYYWGDPRNVSVTLRGSF
>NC_022738.1|WP_023382379.1|4746303_4747464_-|MFS-transporter
MNMRLLAGLLFAVSVVGFSLGASLPLVSLRLHEAGAGTLEIGIISAIPAAGMMLSAFLVDACCRHLTRRVIYLLSFSLCTLSIALLEWAFDSMLWLALLRLGLGVGMGIAIILGESWVNELCPDHNRGKIMALYATSFTGFQVLGPAMLAIIGANSPWITGVVTACYGLALLCILLTVPNDHVEHGDEGEKSFGLAGFFRVAPALCVAVLFFSFFDAVVLSLLPVYATSHGFAVGVAALMVTVVFAGDMVFQLPLGWLADRVERTGLHLVCGLVAMSIGIALPWLLQMTWLLWPLLVLLGAVAGGIYTLALVLIGQRFKGQDLVTANASVGLLWGVGSLVGPLVSGAAMDVAPHGLPMALALMAGMFVCFARQSYRRAGKLRALAD
>NC_022738.1|WP_023382380.1|4747548_4747692_-|hypothetical-protein
MRRTQSLPHARPPAFQAMRRAWPSDTVLKRRRSVLFAFTFSPHLALN
>NC_022738.1|WP_023382381.1|4747821_4749036_-|MFS-transporter
MATSSASTASASGSASHANPLVMRIIAFCALAHLINDLIQSVLPAIYPMLKANYDLSFAQIGLITLTFQITASLLQPWVGFFTDRRPTPNLLPMGTLCTLVGIVMLAFVGSFPMILLASALVGIGSSTFHPETSRIARLASGGRFGLAQSTFQVGGNAGSAFGPLLAAAIVIPFGQSHVAWFGLAGLFFFGVTLMLRRWYKDHLSQAKARKAVQAAHGISRQRVIAALIVLGLLVFSKYFYMASFTSYFTFYLIEKFDLSVASSQLHLFLFLGAVAAGTFFGGPIGDRIGRKAVIWFSILGVAPFTLALPYADLFWTTVLSVVIGFILASAFSAIVVYAQELVPGSVGMIAGVFFGLMFGFGGIGAALLGYVADLRGIEYVYGVCSYLPLFGLLAVFLPNTGKR
>NC_022738.1|WP_023382382.1|4749226_4750150_+|FecR-domain-containing-protein
MPAQQTQREAQQQALEWFSRMRQPGCDDIERREFAAWCQDPLNAHAYAELEALWQHLQPPQVRPRPLPAKPRRSHLGKAMALLCLLLAGALVYLYWPLMQRWGSELHTEAGERRSVRLADGSTLHLDSASAMNVDLRSRTRQLQLVQGQVYLEVMLDGRAMDLQVDDARIQVFGSRLMVARHADHDEVVVINGKAMVIQGGDQRMVSSGERVTFNQARIDTVQKVDIDRATAWRSGALRVTDMPLGQVLERLAGYQGRRVWLMDQQAAYRRISGDFSLDRAQDSLDKLAAAQRLTLNGLLGHWLIVR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1866512 : 1928795

Bacillus_virus(10.0%)

protease,coat

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023379635.1\|1866512_1867796_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	3.7e-138	58.3
WP_023379636.1\|1867948_1870345_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	3.0e-218	52.3
WP_011533117.1\|1870496_1870769_+	DNA-binding protein HU-beta	A3E2K9	Sodalis_phage	2.2e-21	62.9
WP_023379637.1\|1870953_1872825_+	SurA N-terminal domain-containing protein	NA	NA	NA	NA
WP_023379638.1\|1872934_1873975_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_023379639.1\|1874141_1874420_+	hypothetical protein	NA	NA	NA	NA
WP_027906795.1\|1874446_1875205_+	CHAD domain-containing protein	NA	NA	NA	NA
WP_023379642.1\|1875291_1876089_+	thioesterase family protein	NA	NA	NA	NA
WP_023379643.1\|1876126_1876495_-	DUF962 domain-containing protein	NA	NA	NA	NA
WP_023379644.1\|1876570_1878049_-	methyl-accepting chemotaxis protein	NA	NA	NA	NA
WP_023379645.1\|1878137_1878935_-	TatD family hydrolase	NA	NA	NA	NA
WP_023379646.1\|1879094_1880501_+	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_023379647.1\|1880613_1881051_+	DoxX family protein	NA	NA	NA	NA
WP_023379649.1\|1881254_1881563_+	hypothetical protein	NA	NA	NA	NA
WP_023379651.1\|1881641_1882118_+	transcription elongation factor GreB	NA	NA	NA	NA
WP_023379653.1\|1882168_1884676_-	FtsX-like permease family protein	NA	NA	NA	NA
WP_023379655.1\|1884675_1885359_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.7e-07	26.9
WP_023379656.1\|1885369_1885975_+	arylesterase	NA	NA	NA	NA
WP_023379658.1\|1886033_1886315_+	hypothetical protein	NA	NA	NA	NA
WP_023379660.1\|1886421_1887399_+	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_003259780.1\|1887536_1887788_-	hypothetical protein	NA	NA	NA	NA
WP_023379662.1\|1888294_1888576_+	N-acetyltransferase	NA	NA	NA	NA
WP_023379664.1\|1888640_1889717_-	3-deoxy-7-phosphoheptulonate synthase	A0A2I6UFP9	Klebsiella_phage	4.8e-83	50.8
WP_023379666.1\|1889953_1890901_+	putative 2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_023379668.1\|1891005_1891503_+	universal stress protein	NA	NA	NA	NA
WP_023379669.1\|1891632_1892607_+	HTH-type transcriptional regulator CysB	NA	NA	NA	NA
WP_177325263.1\|1892661_1893441_-	phosphoadenylyl-sulfate reductase	NA	NA	NA	NA
WP_023379673.1\|1893527_1894871_-	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	2.2e-48	34.1
WP_023379675.1\|1895055_1896036_-	alpha-L-glutamate ligase-like protein	NA	NA	NA	NA
WP_023379676.1\|1896035_1897571_-	inactive transglutaminase family protein	NA	NA	NA	NA
WP_027907724.1\|1897576_1898113_-\|protease	ATP-dependent zinc protease	NA	NA	NA	NA
WP_023379680.1\|1898406_1899123_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_023379682.1\|1899119_1900010_+	methylisocitrate lyase	NA	NA	NA	NA
WP_023379683.1\|1900111_1901239_+	2-methylcitrate synthase	NA	NA	NA	NA
WP_023379685.1\|1901324_1903913_+	Fe/S-dependent 2-methylisocitrate dehydratase AcnD	NA	NA	NA	NA
WP_023379687.1\|1903988_1905179_+	2-methylaconitate cis-trans isomerase PrpF	NA	NA	NA	NA
WP_023379689.1\|1905247_1906732_+	2-methylcitrate dehydratase	NA	NA	NA	NA
WP_023379691.1\|1906875_1909485_-	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	NA	NA	NA	NA
WP_023379692.1\|1909889_1910369_+	DUF1289 domain-containing protein	NA	NA	NA	NA
WP_015269720.1\|1910472_1910829_-	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_023379694.1\|1910883_1911963_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_023379696.1\|1912162_1912471_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_023379697.1\|1912470_1912785_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_023379699.1\|1912785_1913454_+	response regulator transcription factor	NA	NA	NA	NA
WP_023379700.1\|1913450_1914782_+	sensor histidine kinase	NA	NA	NA	NA
WP_023379701.1\|1914994_1916140_+	HPP family protein	NA	NA	NA	NA
WP_023379702.1\|1916113_1916980_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_023379703.1\|1917160_1919050_+	propionyl-CoA synthetase	A0A2H4PQU7	Staphylococcus_phage	1.5e-55	30.1
WP_023379704.1\|1919227_1920307_-	cell division protein ZapE	NA	NA	NA	NA
WP_023379705.1\|1920489_1920915_+	DUF1810 domain-containing protein	A0A2H4UVK5	Bodo_saltans_virus	3.0e-12	37.4
WP_023379706.1\|1921244_1923632_-	hybrid sensor histidine kinase/response regulator	Q8QNA2	Ectocarpus_siliculosus_virus	2.1e-09	25.5
WP_023379707.1\|1923645_1924107_-	response regulator	NA	NA	NA	NA
WP_023379708.1\|1924120_1926367_-	GAF domain-containing protein	B5LWN8	Feldmannia_species_virus	1.9e-28	23.9
WP_023379709.1\|1926646_1927174_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_023379710.1\|1927202_1927739_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_023379711.1\|1927757_1928288_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_023379712.1\|1928291_1928795_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_2

2018015 : 2123637

162

Pseudomonas_phage(45.22%)

terminase,capsid,head,holin,tRNA,portal,protease,integrase,tail,transposase

attL 2025449:2025491|attR 2127133:2127175

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023379797.1\|2018015_2019938_+\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	2.0e-124	36.9
WP_013972005.1\|2019937_2020489_+	translation initiation factor IF-3	A0A2I7S9Q1	Vibrio_phage	3.2e-14	38.6
WP_003250667.1\|2020549_2020744_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_003250671.1\|2020772_2021129_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_023379798.1\|2021240_2022257_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_023379799.1\|2022288_2024670_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003250679.1\|2024674_2024977_+	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	4.0e-11	38.9
WP_011533210.1\|2024957_2025314_+	MerR family transcriptional regulator	NA	NA	NA	NA
2025449:2025491	attL	NA	NA	NA	NA
WP_023379800.1\|2025573_2026755_-\|integrase	tyrosine-type recombinase/integrase	A0A059VF45	Pseudomonas_phage	1.5e-162	70.6
WP_023379802.1\|2027058_2027235_-	hypothetical protein	A0A2H4J7S3	uncultured_Caudovirales_phage	1.7e-22	84.5
WP_023379803.1\|2027249_2027987_-	metallophosphoesterase	A0A2H4J0P0	uncultured_Caudovirales_phage	1.4e-121	84.0
WP_023379804.1\|2028011_2028329_-	hypothetical protein	NA	NA	NA	NA
WP_023379805.1\|2028385_2028793_-	hypothetical protein	A0A218M341	Acidovorax_phage	1.2e-05	55.8
WP_023379806.1\|2028839_2029193_-	hypothetical protein	NA	NA	NA	NA
WP_023379807.1\|2029189_2029522_-	hypothetical protein	NA	NA	NA	NA
WP_023379808.1\|2029509_2029920_-	DUF2591 domain-containing protein	A0A1B0VMD7	Pseudomonas_phage	9.6e-16	39.1
WP_023379809.1\|2029916_2030429_-	hypothetical protein	A0A1B0VM38	Pseudomonas_phage	4.1e-08	52.3
WP_023379810.1\|2030425_2030677_-	hypothetical protein	A0A2H4J399	uncultured_Caudovirales_phage	6.8e-41	97.6
WP_023379811.1\|2030673_2031468_-	hypothetical protein	Q5QF32	Pseudomonas_virus	1.4e-71	54.2
WP_023379812.1\|2031517_2031670_-	hypothetical protein	NA	NA	NA	NA
WP_023379814.1\|2032051_2032300_-	hypothetical protein	NA	NA	NA	NA
WP_158491096.1\|2032381_2032555_-	hypothetical protein	Q9MC73	Pseudomonas_phage	2.2e-06	59.2
WP_023379815.1\|2032551_2033025_-	single-stranded DNA-binding protein	I3PGW4	Xanthomonas_phage	2.4e-47	57.8
WP_023379816.1\|2033021_2033360_-	hypothetical protein	NA	NA	NA	NA
WP_023379817.1\|2033379_2033763_-	helix-turn-helix transcriptional regulator	A0A2H4JA92	uncultured_Caudovirales_phage	7.5e-23	61.0
WP_023379818.1\|2033919_2034123_-	hypothetical protein	NA	NA	NA	NA
WP_023379819.1\|2034119_2034557_-	tellurite resistance TerB family protein	Q1MVI3	Enterobacteria_phage	1.2e-45	63.6
WP_041925618.1\|2034909_2035653_-	helix-turn-helix transcriptional regulator	A0A059VA53	Pseudomonas_phage	9.0e-81	66.5
WP_023379821.1\|2035740_2035950_+	helix-turn-helix domain-containing protein	H2BD64	Pseudomonas_phage	1.8e-15	68.6
WP_148299909.1\|2036005_2036245_-	hypothetical protein	NA	NA	NA	NA
WP_084212809.1\|2036274_2037066_+	replication protein	W6MYB0	Pseudomonas_phage	5.7e-41	58.0
WP_023379824.1\|2037058_2038441_+	replicative DNA helicase	H2BD70	Pseudomonas_phage	6.7e-122	50.7
WP_023379825.1\|2038437_2038647_+	hypothetical protein	NA	NA	NA	NA
WP_023379826.1\|2038628_2038925_+	DUF1364 domain-containing protein	Q8HAF2	Salmonella_phage	1.8e-32	67.0
WP_158491097.1\|2038921_2039092_+	hypothetical protein	NA	NA	NA	NA
WP_023379827.1\|2039088_2039517_+	VRR-NUC domain-containing protein	A0A2D1GNH3	Pseudomonas_phage	1.0e-44	67.9
WP_023379828.1\|2039513_2040815_+\|integrase	site-specific integrase	A0A2D1GND4	Pseudomonas_phage	4.1e-177	73.0
WP_023379829.1\|2040811_2041147_+	hypothetical protein	A0A2D1GNG3	Pseudomonas_phage	3.5e-16	42.6
WP_023379830.1\|2041157_2041844_+	hypothetical protein	A0A1B0VMF2	Pseudomonas_phage	1.5e-85	66.7
WP_023379831.1\|2042004_2042514_+	hypothetical protein	NA	NA	NA	NA
WP_023379832.1\|2042544_2042868_+\|holin	phage holin, lambda family	A0A1W6JTC7	Pseudomonas_phage	5.2e-25	52.5
WP_023379833.1\|2042871_2043090_+	hypothetical protein	NA	NA	NA	NA
WP_023379834.1\|2043150_2043330_+	hypothetical protein	NA	NA	NA	NA
WP_041925459.1\|2043320_2043692_+	HNH endonuclease	H2BDK0	Pseudomonas_virus	3.7e-19	63.4
WP_023379836.1\|2043776_2044262_+\|terminase	phage terminase small subunit P27 family	A0A2D1GNP3	Pseudomonas_phage	5.2e-69	79.9
WP_023379837.1\|2044261_2045986_+\|terminase	terminase large subunit	A0A2D1GNU5	Pseudomonas_phage	5.6e-291	84.4
WP_023379838.1\|2045985_2047386_+\|portal	phage portal protein	A0A0U4IJ43	Pseudomonas_phage	4.6e-227	84.3
WP_023379839.1\|2047399_2048275_+\|protease	Clp protease ClpP	A0A0U4B0J0	Pseudomonas_phage	1.5e-114	73.5
WP_023379840.1\|2048289_2049504_+\|capsid	phage major capsid protein	A0A0U4JIW8	Pseudomonas_phage	7.6e-186	83.8
WP_023379841.1\|2049548_2049926_+	hypothetical protein	K7PHI6	Enterobacteria_phage	2.1e-09	63.8
WP_023379842.1\|2049929_2050406_+\|head,tail	phage gp6-like head-tail connector protein	G3ENA1	Psychrobacter_phage	7.7e-17	39.0
WP_023379843.1\|2050405_2050747_+\|head	phage head closure protein	B5WZS5	Pseudomonas_phage	2.0e-22	51.3
WP_023379844.1\|2050739_2051234_+	HK97 gp10 family phage protein	A0A0U3TGT7	Pseudomonas_phage	6.7e-64	77.2
WP_041925460.1\|2051230_2051599_+	DUF3168 domain-containing protein	Q9MCA6	Pseudomonas_phage	3.0e-37	59.8
WP_023379846.1\|2051732_2051978_-	hypothetical protein	NA	NA	NA	NA
WP_023379847.1\|2052168_2052894_+	hypothetical protein	H2BDC0	Pseudomonas_virus	7.0e-46	46.4
WP_023379848.1\|2052902_2053370_+\|tail	phage tail assembly chaperone family protein, TAC	Q9MCA4	Pseudomonas_phage	1.9e-36	65.6
WP_084212810.1\|2053345_2053591_+	hypothetical protein	A0A0U4J8S9	Pseudomonas_phage	2.0e-13	49.4
WP_041925619.1\|2053681_2054011_+	superinfection immunity protein	A0A0A7HBY6	Escherichia_phage	2.0e-08	48.3
WP_023379851.1\|2054064_2056620_+\|tail	phage tail tape measure protein	A0A2H4PI09	Pseudomonas_phage	2.4e-221	58.3
WP_023379852.1\|2056619_2056967_+\|tail	phage tail protein	A0A2D1GNJ1	Pseudomonas_phage	3.4e-30	56.1
WP_023379853.1\|2057004_2057706_+\|tail	phage minor tail protein L	A0A2D1GNF3	Pseudomonas_phage	1.1e-104	77.4
WP_023379854.1\|2057708_2058491_+	C40 family peptidase	A0A2D1GNP8	Pseudomonas_phage	1.2e-123	75.0
WP_023379855.1\|2058487_2059072_+\|tail	tail assembly protein	A0A2D1GNM2	Pseudomonas_phage	4.0e-68	67.9
WP_023379856.1\|2059127_2062655_+\|tail	phage tail protein	A0A2D1GNE3	Pseudomonas_phage	0.0e+00	61.3
WP_148299910.1\|2062651_2063695_+	hypothetical protein	A0A2H4JA10	uncultured_Caudovirales_phage	2.9e-117	60.4
WP_023379858.1\|2063715_2064498_+	hypothetical protein	A0A0S2SY45	Pseudomonas_phage	1.1e-55	49.2
WP_084212896.1\|2064695_2065091_+\|tail	tail fiber assembly protein	A0A2H4J9Z7	uncultured_Caudovirales_phage	2.8e-36	66.7
WP_023379860.1\|2065147_2065594_+	hypothetical protein	A0A2R3UAM8	Myoviridae_environmental_samples	3.8e-34	56.6
WP_023379861.1\|2065590_2066106_+	DUF2514 domain-containing protein	A0A2H4J3Q6	uncultured_Caudovirales_phage	5.7e-42	78.7
WP_023379862.1\|2066102_2066309_-	hypothetical protein	NA	NA	NA	NA
WP_023379863.1\|2066422_2066731_+	hypothetical protein	A0A2H4JER5	uncultured_Caudovirales_phage	2.4e-35	72.2
WP_023379864.1\|2066720_2066927_+	hypothetical protein	A0A2H4J7A7	uncultured_Caudovirales_phage	1.7e-05	43.8
WP_023379865.1\|2067224_2068403_-\|integrase	tyrosine-type recombinase/integrase	A0A059VF45	Pseudomonas_phage	9.1e-160	69.8
WP_023379866.1\|2068697_2068874_-	hypothetical protein	A0A2H4J7S3	uncultured_Caudovirales_phage	5.0e-22	82.8
WP_023379867.1\|2068888_2069626_-	metallophosphoesterase	A0A2H4J0P0	uncultured_Caudovirales_phage	2.3e-121	82.4
WP_023379804.1\|2069650_2069968_-	hypothetical protein	NA	NA	NA	NA
WP_023379805.1\|2070024_2070432_-	hypothetical protein	A0A218M341	Acidovorax_phage	1.2e-05	55.8
WP_023379806.1\|2070478_2070832_-	hypothetical protein	NA	NA	NA	NA
WP_023379868.1\|2070828_2071260_-	DUF2591 family protein	NA	NA	NA	NA
WP_023379869.1\|2071304_2071577_-	hypothetical protein	A0A2H4J399	uncultured_Caudovirales_phage	9.7e-25	68.1
WP_023379870.1\|2071579_2072017_-	hypothetical protein	NA	NA	NA	NA
WP_023379812.1\|2072046_2072199_-	hypothetical protein	NA	NA	NA	NA
WP_041925462.1\|2072741_2072975_-	hypothetical protein	NA	NA	NA	NA
WP_041925463.1\|2072955_2073666_-	HNH endonuclease	A0A1S5SDS7	Streptococcus_phage	5.2e-17	28.6
WP_023379872.1\|2073734_2074160_-	hypothetical protein	NA	NA	NA	NA
WP_023379873.1\|2074326_2074569_-	hypothetical protein	A0A2H4J0R5	uncultured_Caudovirales_phage	9.5e-32	90.0
WP_023379874.1\|2074543_2074891_-	hypothetical protein	A0A2H4J0L9	uncultured_Caudovirales_phage	1.7e-45	83.5
WP_158491098.1\|2074932_2075496_-	HNH endonuclease	A0A0G2Y7F9	Acanthamoeba_polyphaga_mimivirus	1.1e-22	38.9
WP_023379876.1\|2075659_2076172_-	hypothetical protein	A0A2H4J7C8	uncultured_Caudovirales_phage	4.0e-11	33.7
WP_023379877.1\|2076179_2076743_-	siphovirus Gp157 family protein	A0A2H4IZG3	uncultured_Caudovirales_phage	7.8e-93	94.7
WP_023379878.1\|2076739_2077471_-	hypothetical protein	A0A2H4J2D5	uncultured_Caudovirales_phage	9.4e-115	86.0
WP_023379880.1\|2077768_2077990_-	hypothetical protein	NA	NA	NA	NA
WP_023379882.1\|2077986_2078202_-	hypothetical protein	NA	NA	NA	NA
WP_023379883.1\|2078198_2078732_-	hypothetical protein	NA	NA	NA	NA
WP_023379884.1\|2078728_2078923_-	hypothetical protein	A0A1B0VMB8	Pseudomonas_phage	1.4e-12	58.1
WP_023379885.1\|2078919_2079342_-	hypothetical protein	NA	NA	NA	NA
WP_023379886.1\|2079620_2079875_-	DUF551 domain-containing protein	NA	NA	NA	NA
WP_023379887.1\|2079871_2080084_-	hypothetical protein	A0A1B0VMC0	Pseudomonas_phage	3.8e-08	44.9
WP_023379888.1\|2080521_2081064_-	hypothetical protein	J7HXB1	Pseudomonas_phage	2.6e-53	59.4
WP_023379889.1\|2081779_2082097_+	DUF1654 domain-containing protein	A0A2D1GND3	Pseudomonas_phage	4.3e-24	55.2
WP_148299912.1\|2082145_2082652_-	hypothetical protein	A0A1B0VMC8	Pseudomonas_phage	7.6e-47	65.4
WP_023379891.1\|2082883_2083462_-	hypothetical protein	NA	NA	NA	NA
WP_023379892.1\|2083451_2083700_-	hypothetical protein	NA	NA	NA	NA
WP_023379893.1\|2083732_2083966_-	hypothetical protein	NA	NA	NA	NA
WP_023379894.1\|2083968_2084850_-	helix-turn-helix domain-containing protein	H2BD63	Pseudomonas_phage	5.9e-47	41.3
WP_041925625.1\|2084955_2085150_+	Cro/Cl family transcriptional regulator	A0A2H4J1L8	uncultured_Caudovirales_phage	1.3e-07	50.0
WP_023379896.1\|2085180_2085393_+	hypothetical protein	A0A2H4J3U0	uncultured_Caudovirales_phage	6.4e-32	100.0
WP_023379897.1\|2085411_2085624_+	hypothetical protein	A0A2H4IZI7	uncultured_Caudovirales_phage	1.9e-28	97.0
WP_041925465.1\|2085722_2086466_+	phage antirepressor KilAC domain-containing protein	A0A059VF66	Pseudomonas_phage	1.8e-100	80.4
WP_023379899.1\|2086465_2087272_+	hypothetical protein	A0A2H4J580	uncultured_Caudovirales_phage	2.7e-147	91.0
WP_023379900.1\|2087261_2088068_+	ATP-binding protein	A0A2H4J3E5	uncultured_Caudovirales_phage	2.4e-143	97.4
WP_012273057.1\|2088067_2088439_+	DUF2493 domain-containing protein	A0A2H4J0K9	uncultured_Caudovirales_phage	1.1e-63	99.2
WP_023379901.1\|2088435_2088627_+	hypothetical protein	A0A2H4IZH6	uncultured_Caudovirales_phage	5.6e-27	98.4
WP_023379902.1\|2088856_2089129_+	hypothetical protein	A0A2H4JG78	uncultured_Caudovirales_phage	6.8e-18	58.5
WP_023379903.1\|2089125_2089425_+	hypothetical protein	A0A2H4J8S0	uncultured_Caudovirales_phage	7.4e-50	100.0
WP_023379904.1\|2089417_2089816_+	recombination protein NinB	A0A059VG13	Pseudomonas_phage	3.8e-62	84.1
WP_023379905.1\|2089815_2090418_+	recombination protein NinG	L7TH85	Pseudomonas_virus	3.1e-55	56.9
WP_023379906.1\|2090533_2091223_+	hypothetical protein	Q9MC44	Pseudomonas_phage	3.6e-47	45.8
WP_023379907.1\|2091212_2091647_+	hypothetical protein	NA	NA	NA	NA
WP_023379909.1\|2091707_2091971_+	hypothetical protein	NA	NA	NA	NA
WP_046854952.1\|2091981_2092371_+	hypothetical protein	A0A2H4J7X6	uncultured_Caudovirales_phage	3.2e-21	43.8
WP_023379912.1\|2092367_2092670_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_023379913.1\|2092713_2093100_-	hypothetical protein	A0A0S2SYH9	Pseudomonas_phage	5.4e-53	86.7
WP_023379914.1\|2093152_2093350_-	hypothetical protein	NA	NA	NA	NA
WP_041925467.1\|2093423_2094032_+	hypothetical protein	A0A0S2SYA5	Pseudomonas_phage	2.8e-96	82.7
WP_023379917.1\|2094062_2094539_+	DUF2280 domain-containing protein	A0A1B0VMH2	Pseudomonas_phage	3.5e-70	82.9
WP_023379919.1\|2094513_2095833_+\|terminase	phage terminase	A0A0S2SYF1	Pseudomonas_phage	1.4e-249	93.8
WP_023379921.1\|2097240_2098317_+	hypothetical protein	A0A0H5BBX3	Pseudomonas_phage	5.7e-100	52.6
WP_013972415.1\|2098470_2099217_+	hypothetical protein	A0A0H5AWD1	Pseudomonas_phage	3.5e-93	77.2
WP_013972416.1\|2099226_2100195_+	hypothetical protein	A0A0H5ARK0	Pseudomonas_phage	1.4e-142	79.8
WP_023379923.1\|2100236_2100533_+	hypothetical protein	A0A0H5BBX8	Pseudomonas_phage	1.0e-06	53.3
WP_023379924.1\|2100532_2100901_+	hypothetical protein	A0A0S2SYB7	Pseudomonas_phage	5.4e-26	53.5
WP_023379926.1\|2100902_2101289_+	hypothetical protein	A0A2H4IZB5	uncultured_Caudovirales_phage	6.8e-40	63.8
WP_023379928.1\|2101291_2101963_+	hypothetical protein	A0A2H4J0Q3	uncultured_Caudovirales_phage	2.3e-59	53.6
WP_023379929.1\|2101959_2102388_+	hypothetical protein	A0A2H4J5P1	uncultured_Caudovirales_phage	6.6e-68	93.5
WP_023379931.1\|2102427_2103087_+\|tail	phage tail protein	A0A0S2SYG8	Pseudomonas_phage	4.1e-85	72.4
WP_023379933.1\|2103096_2103480_+\|tail	phage tail assembly chaperone	A0A2H4IYQ5	uncultured_Caudovirales_phage	6.3e-38	57.5
WP_049818804.1\|2103542_2103794_+	DUF1799 domain-containing protein	A0A2H4JBP7	uncultured_Caudovirales_phage	5.1e-28	77.8
WP_023379936.1\|2103797_2107199_+\|tail	phage tail tape measure protein	A0A2H4J9A1	uncultured_Caudovirales_phage	2.7e-204	53.2
WP_023379938.1\|2107198_2107537_+\|tail	phage tail protein	A0A2H4JI07	uncultured_Caudovirales_phage	4.0e-44	72.3
WP_023379939.1\|2107546_2108296_+\|tail	phage minor tail protein L	A0A0S2SY57	Pseudomonas_phage	1.1e-121	77.1
WP_023379940.1\|2108298_2109054_+	C40 family peptidase	A0A2H4J1J7	uncultured_Caudovirales_phage	6.7e-124	78.5
WP_023379941.1\|2109078_2109282_+	hypothetical protein	NA	NA	NA	NA
WP_023379942.1\|2109278_2109491_-	hypothetical protein	NA	NA	NA	NA
WP_148299913.1\|2109767_2110157_+	hypothetical protein	NA	NA	NA	NA
WP_023379944.1\|2110271_2110862_+	hypothetical protein	NA	NA	NA	NA
WP_023379945.1\|2111162_2111591_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_023379946.1\|2111719_2112139_+	hypothetical protein	J9Q806	Salmonella_phage	2.3e-25	42.5
WP_023379947.1\|2112181_2112766_+\|tail	tail assembly protein	A0A2H4J1H0	uncultured_Caudovirales_phage	8.1e-77	76.8
WP_023379948.1\|2112821_2116289_+	DUF1983 domain-containing protein	A0A2H4J8Z6	uncultured_Caudovirales_phage	0.0e+00	55.0
WP_023379949.1\|2116285_2116600_+	hypothetical protein	NA	NA	NA	NA
WP_023379950.1\|2116600_2117476_+	hypothetical protein	NA	NA	NA	NA
WP_023379951.1\|2117491_2118274_+	hypothetical protein	A0A0S2SY45	Pseudomonas_phage	9.9e-54	47.7
WP_084212899.1\|2118471_2118867_+\|tail	tail fiber assembly protein	A0A2H4J9Z7	uncultured_Caudovirales_phage	3.6e-36	67.4
WP_023379953.1\|2118924_2119371_+	hypothetical protein	A0A2R3UAM8	Myoviridae_environmental_samples	1.2e-35	57.9
WP_023379954.1\|2119367_2119865_+	DUF2514 domain-containing protein	A0A2H4J3Q6	uncultured_Caudovirales_phage	1.0e-43	78.8
WP_041925629.1\|2119878_2120103_+	hypothetical protein	A0A2H4JG60	uncultured_Caudovirales_phage	6.5e-27	79.7
WP_023379863.1\|2120182_2120491_+	hypothetical protein	A0A2H4JER5	uncultured_Caudovirales_phage	2.4e-35	72.2
WP_023379956.1\|2120480_2120687_+	hypothetical protein	A0A2H4J7A7	uncultured_Caudovirales_phage	1.7e-05	43.8
WP_023379379.1\|2121344_2122145_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	2.9e-32	35.5
WP_167332798.1\|2122137_2123637_-\|transposase	IS21 family transposase	NA	NA	NA	NA
2127133:2127175	attR	NA	NA	NA	NA

DBSCAN-SWA_3

3265495 : 3274982

uncultured_Caudovirales_phage(71.43%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023381076.1\|3265495_3266782_-	HAMP domain-containing protein	W8CYF6	Bacillus_phage	2.5e-09	22.8
WP_023381077.1\|3266847_3267555_-	response regulator	NA	NA	NA	NA
WP_023381078.1\|3267721_3268504_+	VacJ family lipoprotein	NA	NA	NA	NA
WP_023381079.1\|3268496_3268745_+	hypothetical protein	NA	NA	NA	NA
WP_023381080.1\|3268828_3269221_+	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	3.5e-52	78.3
WP_023381081.1\|3269222_3269582_+	sulfurtransferase complex subunit TusC	A0A2H4J8C0	uncultured_Caudovirales_phage	2.5e-36	65.0
WP_023381082.1\|3269581_3269878_+	sulfurtransferase complex subunit TusB	A0A2H4JG28	uncultured_Caudovirales_phage	3.0e-27	64.6
WP_023381083.1\|3269874_3270210_+	TusE/DsrC/DsvC family sulfur relay protein	A0A2H4J8B6	uncultured_Caudovirales_phage	4.4e-43	75.7
WP_023381084.1\|3270206_3271223_+	glycosyl transferase family protein	A0A2H4JBY5	uncultured_Caudovirales_phage	1.1e-153	78.9
WP_023381085.1\|3271317_3272277_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_023381086.1\|3272309_3273701_-	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_023381087.1\|3273701_3274982_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.2e-94	45.3

DBSCAN-SWA_4

4109877 : 4161752

Pseudomonas_phage(53.66%)

head,capsid,terminase,protease,portal,integrase,tail

attL 4121315:4121374|attR 4161858:4161924

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023381809.1\|4109877_4111440_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_023381810.1\|4111886_4113725_+	hypothetical protein	NA	NA	NA	NA
WP_041925533.1\|4113969_4114884_+	replication initiation protein	NA	NA	NA	NA
WP_041925534.1\|4116056_4116437_+	hypothetical protein	NA	NA	NA	NA
WP_084212857.1\|4116669_4118376_+	shufflon system plasmid conjugative transfer pilus tip adhesin PilV	A0A1D8KUN9	Synechococcus_phage	9.8e-14	36.3
WP_148299925.1\|4118440_4119112_+	hypothetical protein	NA	NA	NA	NA
WP_148299926.1\|4119505_4119859_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_148299927.1\|4120540_4120897_-	hypothetical protein	NA	NA	NA	NA
4121315:4121374	attL	NA	NA	NA	NA
WP_158239721.1\|4121724_4121877_+	hypothetical protein	NA	NA	NA	NA
WP_023381813.1\|4122010_4122364_-	hypothetical protein	NA	NA	NA	NA
WP_023381814.1\|4122515_4122740_-	hypothetical protein	A0A2H4JG60	uncultured_Caudovirales_phage	2.7e-28	86.5
WP_023381815.1\|4122782_4123316_-	DUF2514 family protein	NA	NA	NA	NA
WP_023381816.1\|4123312_4123759_-	hypothetical protein	A0A2R3UAM8	Myoviridae_environmental_samples	3.0e-39	57.8
WP_084212918.1\|4123822_4124218_-\|tail	tail fiber assembly protein	A0A2H4J9Z7	uncultured_Caudovirales_phage	6.1e-36	61.8
WP_023381818.1\|4124415_4125204_-	hypothetical protein	A0A0S2SY45	Pseudomonas_phage	1.8e-50	48.9
WP_023381819.1\|4125219_4126095_-	hypothetical protein	NA	NA	NA	NA
WP_023381820.1\|4126095_4126410_-	hypothetical protein	NA	NA	NA	NA
WP_023381821.1\|4126406_4129862_-	DUF1983 domain-containing protein	A0A2D1GNE3	Pseudomonas_phage	8.9e-256	43.8
WP_023381822.1\|4129870_4130494_-\|tail	tail assembly protein	C7BGD3	Burkholderia_phage	1.8e-42	48.5
WP_041925724.1\|4130939_4131698_-	C40 family peptidase	A0A2I6PI52	Pseudomonas_phage	6.4e-58	46.7
WP_023381825.1\|4131713_4132412_-\|tail	phage minor tail protein L	A0A2I6PIA7	Pseudomonas_phage	1.5e-53	45.4
WP_023381826.1\|4132411_4132750_-\|tail	phage tail protein	K7P7R1	Enterobacteria_phage	3.0e-23	48.6
WP_023381827.1\|4132770_4135272_-\|tail	phage tail tape measure protein	D4FUM0	Pseudomonas_phage	1.6e-129	49.1
WP_023381829.1\|4135541_4136009_-\|tail	phage tail assembly chaperone family protein, TAC	K7PJU9	Enterobacteria_phage	2.3e-34	59.7
WP_023381830.1\|4136017_4136509_-\|tail	phage major tail protein	H2BDC0	Pseudomonas_virus	5.3e-53	64.7
WP_023381831.1\|4136698_4136944_+	hypothetical protein	NA	NA	NA	NA
WP_023381832.1\|4137077_4137446_-	DUF3168 domain-containing protein	Q9MCA6	Pseudomonas_phage	1.2e-38	61.5
WP_023381833.1\|4137442_4137937_-	HK97 gp10 family phage protein	A0A0U3TGT7	Pseudomonas_phage	5.1e-64	77.0
WP_023381834.1\|4137929_4138271_-\|head	phage head closure protein	B5WZS5	Pseudomonas_phage	3.3e-22	48.7
WP_023381835.1\|4138270_4138747_-\|head,tail	phage gp6-like head-tail connector protein	G3ENA1	Psychrobacter_phage	1.5e-17	37.4
WP_023381836.1\|4138750_4138972_-	hypothetical protein	NA	NA	NA	NA
WP_023381837.1\|4139013_4140270_-\|capsid	phage major capsid protein	Q6JIM7	Burkholderia_virus	2.5e-91	49.0
WP_023381838.1\|4140279_4140981_-\|head,protease	HK97 family phage prohead protease	Q6JIM8	Burkholderia_virus	2.5e-72	61.5
WP_023381839.1\|4140977_4142312_-\|portal	phage portal protein	Q6JIM9	Burkholderia_virus	2.6e-131	56.1
WP_010952648.1\|4142304_4142469_-	hypothetical protein	NA	NA	NA	NA
WP_023381840.1\|4142480_4144190_-\|terminase	terminase large subunit	A0A0R6PIM0	Moraxella_phage	5.2e-233	68.4
WP_010952646.1\|4144189_4144573_-\|terminase	phage terminase small subunit	Q9XJT7	Pseudomonas_phage	3.9e-19	44.2
WP_023381841.1\|4144700_4145069_-	HNH endonuclease	H2BDK0	Pseudomonas_virus	4.9e-19	59.8
WP_023381842.1\|4145059_4145239_-	hypothetical protein	NA	NA	NA	NA
WP_023381843.1\|4145299_4145617_-	hypothetical protein	A0A059VJW1	Pseudomonas_phage	5.3e-14	54.7
WP_023381844.1\|4145616_4145988_-	hypothetical protein	A0A059VK40	Pseudomonas_phage	2.8e-38	84.6
WP_023381845.1\|4146015_4146669_-	hypothetical protein	A0A2H4J0P2	uncultured_Caudovirales_phage	1.3e-14	37.2
WP_158491102.1\|4147113_4147536_+	hypothetical protein	NA	NA	NA	NA
WP_023381848.1\|4147833_4148445_-	hypothetical protein	A0A2H4J2J2	uncultured_Caudovirales_phage	7.5e-57	49.8
WP_023381849.1\|4148441_4148948_-	hypothetical protein	NA	NA	NA	NA
WP_023381850.1\|4148934_4150317_-	AAA family ATPase	A0A2H4J8N1	uncultured_Caudovirales_phage	1.4e-140	57.8
WP_023381851.1\|4150313_4151096_-	ATP-binding protein	A0A0A0YRV1	Pseudomonas_phage	5.6e-89	61.4
WP_023381852.1\|4151092_4151887_-	hypothetical protein	A0A2H4J580	uncultured_Caudovirales_phage	5.0e-29	51.9
WP_023381853.1\|4151883_4152114_-	hypothetical protein	A0A1W6JTF8	Pseudomonas_phage	1.6e-15	53.9
WP_023381854.1\|4152110_4152725_-	hypothetical protein	A0A1B0VMK2	Pseudomonas_phage	5.8e-33	40.3
WP_023381855.1\|4152721_4153492_-	ORF6N domain-containing protein	A0A1B5FPC0	Escherichia_phage	1.4e-23	53.1
WP_023381856.1\|4153488_4153785_-	hypothetical protein	NA	NA	NA	NA
WP_023381857.1\|4154089_4154425_-	hypothetical protein	NA	NA	NA	NA
WP_023381858.1\|4154831_4155365_-	KilA-N domain-containing protein	A0A0H5ARR4	Pseudomonas_phage	8.8e-38	46.9
WP_023381859.1\|4155361_4155658_-	regulatory protein cro	A0A0U1UNM4	Pseudomonas_phage	2.4e-13	59.1
WP_041925731.1\|4155763_4156510_+	LexA family transcriptional regulator	A0A0U1SXS9	Pseudomonas_phage	1.2e-40	40.6
WP_023381861.1\|4156649_4157045_+	DUF134 domain-containing protein	A0A0A0YWH0	Pseudomonas_phage	1.2e-34	69.2
WP_023381862.1\|4157141_4157333_+	carbon storage regulator CsrA	J7I430	Pseudomonas_phage	1.8e-09	64.7
WP_023381863.1\|4157322_4157550_+	Arc family DNA-binding protein	A0A1W6JTB4	Pseudomonas_phage	1.3e-09	57.6
WP_023381864.1\|4157536_4158097_+	hypothetical protein	NA	NA	NA	NA
WP_023381865.1\|4158093_4158237_+	hypothetical protein	NA	NA	NA	NA
WP_023381867.1\|4158604_4158853_+	hypothetical protein	B5WZU8	Pseudomonas_phage	1.6e-13	53.9
WP_023381868.1\|4158868_4159588_-	hypothetical protein	NA	NA	NA	NA
WP_084212860.1\|4159588_4160734_-	ATP-binding protein	NA	NA	NA	NA
WP_041925735.1\|4160774_4161752_-\|integrase	site-specific integrase	W6MYA3	Pseudomonas_phage	5.4e-126	70.5
4161858:4161924	attR	NA	NA	NA	NA

DBSCAN-SWA_5

4547944 : 4579871

uncultured_Mediterranean_phage(15.79%)

head,capsid,terminase,tRNA,protease,portal,integrase,tail

attL 4544467:4544486|attR 4588282:4588301

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4544467:4544486	attL	NA	NA	NA	NA
WP_023382203.1\|4547944_4549234_-\|tRNA	histidine--tRNA ligase	A0A2I2L577	Orpheovirus	2.5e-25	25.3
WP_023382204.1\|4549258_4550368_-	flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	NA	NA	NA	NA
WP_023382205.1\|4550371_4551421_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_023382206.1\|4551417_4552179_-	type IV pilus biogenesis/stability protein PilW	NA	NA	NA	NA
WP_027906606.1\|4552193_4553339_-	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	NA	NA	NA	NA
WP_023382208.1\|4553363_4553795_-	nucleoside-diphosphate kinase	A0A167REB2	Powai_lake_megavirus	9.7e-19	40.9
WP_023382209.1\|4553884_4554085_-	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_023382210.1\|4554095_4554437_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_023382212.1\|4554440_4556303_-	Fe-S protein assembly chaperone HscA	F2Y2E1	Organic_Lake_phycodnavirus	5.9e-105	40.8
WP_023382213.1\|4556345_4556867_-	co-chaperone HscB	NA	NA	NA	NA
WP_003257854.1\|4556875_4557199_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	1.5e-24	50.5
WP_007929523.1\|4557231_4557618_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	2.7e-52	77.4
WP_023382214.1\|4557664_4558879_-	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	5.1e-33	30.3
WP_023382215.1\|4558932_4559424_-	Fe-S cluster assembly transcriptional regulator IscR	NA	NA	NA	NA
WP_023382216.1\|4559603_4560389_-	serine O-acetyltransferase	NA	NA	NA	NA
WP_023382217.1\|4560392_4561163_-\|tRNA	tRNA (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ	NA	NA	NA	NA
WP_023382218.1\|4561314_4562133_+	inositol monophosphatase	NA	NA	NA	NA
WP_023382219.1\|4562231_4562774_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_023382220.1\|4562893_4563802_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	2.9e-49	43.0
WP_023382221.1\|4563812_4565675_-	protein translocase subunit SecD	NA	NA	NA	NA
WP_023382222.1\|4565738_4566074_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	2.9e-10	42.4
WP_023382223.1\|4566116_4567232_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	3.3e-95	49.3
WP_023382224.1\|4567246_4568296_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_023382225.1\|4568695_4569904_+\|integrase	tyrosine-type recombinase/integrase	A0A1B0VMI6	Pseudomonas_phage	2.0e-154	69.2
WP_023382226.1\|4569903_4570698_+	hypothetical protein	NA	NA	NA	NA
WP_023382227.1\|4570807_4571032_+	AlpA family phage regulatory protein	A0A1B0VNF0	Pseudomonas_phage	6.6e-19	73.8
WP_023382228.1\|4571424_4571583_+	hypothetical protein	A0A1B0VP73	Pseudomonas_phage	3.0e-10	67.3
WP_023382229.1\|4571579_4571906_+	hypothetical protein	NA	NA	NA	NA
WP_023382230.1\|4571908_4572316_+	virulence-associated protein E	NA	NA	NA	NA
WP_023382231.1\|4572312_4573566_+	AAA family ATPase	NA	NA	NA	NA
WP_023382232.1\|4573562_4573856_+	hypothetical protein	NA	NA	NA	NA
WP_023382233.1\|4573974_4575177_+\|capsid	phage major capsid protein	F4YCR7	Synechococcus_phage	8.4e-44	36.7
WP_023382234.1\|4575176_4575698_+\|head,protease	HK97 family phage prohead protease	B4UTP2	Rhizobium_phage	2.3e-30	45.9
WP_023382235.1\|4575694_4576927_+\|portal	phage portal protein	Q6DMU2	Streptococcus_phage	1.0e-60	35.7
WP_023382236.1\|4576923_4577262_+	HNH endonuclease	H9YSB8	environmental_Halophage	1.5e-06	41.2
WP_023382237.1\|4577321_4577783_+	hypothetical protein	NA	NA	NA	NA
WP_023382238.1\|4577779_4579276_+\|terminase	phage terminase large subunit	F1C585	Cronobacter_phage	3.4e-180	62.9
WP_023382239.1\|4579272_4579554_+\|head,tail	phage gp6-like head-tail connector protein	A0A2H4J711	uncultured_Caudovirales_phage	1.4e-05	36.3
WP_023382240.1\|4579553_4579871_+\|head	phage head closure protein	Q3HQT3	Burkholderia_phage	3.9e-09	38.7
4588282:4588301	attR	NA	NA	NA	NA

DBSCAN-SWA_6

5238076 : 5309994

Pseudomonas_phage(67.74%)

head,terminase,capsid,plate,lysis,holin,portal,integrase,tail,transposase

attL 5293260:5293275|attR 5308634:5308649

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023382784.1\|5238076_5239021_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_023382785.1\|5239144_5240029_+	3-keto-5-aminohexanoate cleavage protein	NA	NA	NA	NA
WP_023382786.1\|5240050_5241016_+	L-carnitine dehydrogenase	NA	NA	NA	NA
WP_023382787.1\|5241026_5241497_+	thioesterase family protein	NA	NA	NA	NA
WP_023382788.1\|5241855_5242113_+	hypothetical protein	NA	NA	NA	NA
WP_023382789.1\|5242196_5243303_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_023382790.1\|5243696_5245073_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_023382791.1\|5245515_5246463_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_177325271.1\|5246545_5247394_+\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_023382793.1\|5247390_5248569_+\|holin	choline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.2e-24	36.2
WP_011536177.1\|5248665_5249436_-	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_023382794.1\|5249446_5250184_-	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	NA	NA	NA	NA
WP_023382795.1\|5250211_5250472_-	DUF2164 domain-containing protein	NA	NA	NA	NA
WP_023382796.1\|5250472_5251111_-	imidazole glycerol phosphate synthase subunit HisH	NA	NA	NA	NA
WP_023382797.1\|5251111_5251705_-	imidazoleglycerol-phosphate dehydratase HisB	NA	NA	NA	NA
WP_023382798.1\|5251919_5253578_-	OFA family MFS transporter	NA	NA	NA	NA
WP_023382799.1\|5253899_5256137_+	AsmA family protein	NA	NA	NA	NA
WP_023382800.1\|5256133_5257201_+	A/G-specific adenine glycosylase	NA	NA	NA	NA
WP_023382801.1\|5257197_5257470_+	oxidative damage protection protein	NA	NA	NA	NA
WP_162144451.1\|5257974_5258856_+	polyphosphate kinase 2	NA	NA	NA	NA
WP_023382803.1\|5258909_5259353_+	hypothetical protein	NA	NA	NA	NA
WP_023382804.1\|5259495_5260884_-	GABA permease	NA	NA	NA	NA
WP_023382806.1\|5261490_5262264_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.9e-21	32.4
WP_023382807.1\|5262275_5263028_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_023382808.1\|5263083_5263776_+	ABC transporter permease	NA	NA	NA	NA
WP_023382809.1\|5263775_5264465_+	ABC transporter permease	NA	NA	NA	NA
WP_023382810.1\|5264537_5265743_+	methyltransferase	NA	NA	NA	NA
WP_023382811.1\|5266070_5266343_-	DUF3077 domain-containing protein	NA	NA	NA	NA
WP_023382812.1\|5266348_5266615_-	hypothetical protein	NA	NA	NA	NA
WP_023382813.1\|5267136_5267385_+	hypothetical protein	NA	NA	NA	NA
WP_041925764.1\|5268182_5268533_+	hypothetical protein	NA	NA	NA	NA
WP_023382815.1\|5268606_5268852_+	hypothetical protein	NA	NA	NA	NA
WP_023382817.1\|5269667_5269898_+	hypothetical protein	NA	NA	NA	NA
WP_023382818.1\|5269909_5270206_+	hypothetical protein	NA	NA	NA	NA
WP_023382819.1\|5271136_5272108_-	hypothetical protein	A0A0U4IBV2	Pseudomonas_phage	1.6e-122	67.5
WP_023382820.1\|5272080_5272785_-	hypothetical protein	A0A2I7RNK1	Vibrio_phage	2.4e-38	39.0
WP_023382821.1\|5272781_5273327_-	hypothetical protein	A0A0U4J942	Pseudomonas_phage	1.3e-47	57.4
WP_041925765.1\|5273323_5274247_-	hypothetical protein	NA	NA	NA	NA
WP_023382823.1\|5274243_5274951_-	hypothetical protein	A0A0U4JEJ6	Pseudomonas_phage	5.1e-57	46.8
WP_023382824.1\|5274958_5276923_-\|tail	phage tail protein	A0A0U4K5K2	Pseudomonas_phage	4.0e-136	49.0
WP_023382825.1\|5276933_5277458_-	hypothetical protein	A0A0U4JVX3	Pseudomonas_phage	6.8e-75	75.9
WP_023382826.1\|5277454_5278621_-\|plate	baseplate J/gp47 family protein	A0A0U4JJ14	Pseudomonas_phage	3.2e-157	72.4
WP_023382827.1\|5278617_5278941_-	DUF2590 family protein	A0A0U4B0N5	Pseudomonas_phage	7.2e-35	76.4
WP_023382828.1\|5278940_5281010_-\|tail	phage tail tape measure protein	A0A0U4IJ81	Pseudomonas_phage	8.8e-134	41.8
WP_023382829.1\|5281184_5281472_-	hypothetical protein	A0A0U4B0P2	Pseudomonas_phage	1.9e-18	53.8
WP_023382830.1\|5281468_5281960_-\|lysis	lysis protein	A0A0U4JXC2	Pseudomonas_phage	2.2e-19	44.3
WP_023382831.1\|5281956_5282487_-	lysozyme	NA	NA	NA	NA
WP_041925563.1\|5282483_5282765_-	hypothetical protein	NA	NA	NA	NA
WP_023382833.1\|5282761_5282977_-	TraR/DksA C4-type zinc finger protein	A0A0U4IIN4	Pseudomonas_phage	1.0e-13	58.2
WP_023382834.1\|5282976_5283426_-	DUF2597 family protein	A0A0U3TH58	Pseudomonas_phage	1.8e-60	75.8
WP_023382835.1\|5283432_5284542_-	DUF2586 family protein	A0A0U4KLE6	Pseudomonas_phage	2.1e-134	65.3
WP_023382836.1\|5284553_5285234_-	phage virion morphogenesis protein	A0A0U4ISN1	Pseudomonas_phage	4.3e-61	59.6
WP_023382837.1\|5285223_5285679_-\|tail	phage tail protein	A0A0U4IBS7	Pseudomonas_phage	4.9e-45	62.0
WP_023382838.1\|5285675_5286137_-\|head	head completion/stabilization protein	A0A0U4J933	Pseudomonas_phage	6.7e-42	57.5
WP_023382839.1\|5286233_5286968_-\|terminase	terminase endonuclease subunit	A0A0U4JEJ1	Pseudomonas_phage	3.9e-76	64.1
WP_023382840.1\|5286964_5287987_-\|capsid	phage major capsid protein, P2 family	A0A0U4K5I9	Pseudomonas_phage	3.0e-119	64.2
WP_023382841.1\|5287988_5288930_-\|capsid	GPO family capsid scaffolding protein	A0A0U4JVV6	Pseudomonas_phage	4.4e-64	58.9
WP_084212880.1\|5290986_5291928_+\|portal	phage portal protein	A0A0U4B0L9	Pseudomonas_phage	2.2e-100	75.8
WP_023382844.1\|5291999_5292260_+	ogr/Delta-like zinc finger family protein	A5X9H0	Aeromonas_virus	3.3e-14	43.4
WP_023382846.1\|5292577_5292916_-	helix-turn-helix domain-containing protein	A0A2H4JFL3	uncultured_Caudovirales_phage	1.9e-17	44.0
WP_041925564.1\|5293000_5293201_+	DNA-binding protein	A0A2H4JE67	uncultured_Caudovirales_phage	2.1e-08	47.7
WP_023382848.1\|5293231_5293711_+	hypothetical protein	Q9ZXJ2	Pseudomonas_virus	1.1e-34	51.3
5293260:5293275	attL	NA	NA	NA	NA
WP_023382849.1\|5293707_5293947_+	hypothetical protein	NA	NA	NA	NA
WP_023382850.1\|5294014_5294248_+	hypothetical protein	NA	NA	NA	NA
WP_023382851.1\|5294256_5296944_+	toprim domain-containing protein	A0A2H4J936	uncultured_Caudovirales_phage	2.9e-270	52.1
WP_023382852.1\|5296949_5297252_+	hypothetical protein	NA	NA	NA	NA
WP_051376146.1\|5297382_5297610_+	hypothetical protein	NA	NA	NA	NA
WP_041925769.1\|5297639_5298020_+	DUF2528 family protein	NA	NA	NA	NA
WP_023382855.1\|5298016_5298250_+	hypothetical protein	NA	NA	NA	NA
WP_023382856.1\|5298391_5298604_+	hypothetical protein	NA	NA	NA	NA
WP_023382857.1\|5298600_5299773_+\|integrase	integrase	V9IQN0	Stenotrophomonas_phage	2.7e-71	38.9
WP_023382858.1\|5300079_5301399_+\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A1B0VMI6	Pseudomonas_phage	3.7e-69	40.0
WP_023382859.1\|5302200_5303184_+	hypothetical protein	NA	NA	NA	NA
WP_023382860.1\|5303180_5303864_+	hypothetical protein	NA	NA	NA	NA
WP_023382862.1\|5305167_5306148_+\|integrase	integrase domain-containing protein	NA	NA	NA	NA
WP_023382863.1\|5306503_5307466_-	hypothetical protein	NA	NA	NA	NA
WP_023379379.1\|5307701_5308502_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	2.9e-32	35.5
WP_167332798.1\|5308494_5309994_-\|transposase	IS21 family transposase	NA	NA	NA	NA
5308634:5308649	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_022739

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_022739_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_022739_1

292120-292232

Orphan

Consensus_repeat	Method
GACGCTGCACCTGTTCAAGCCAGCCAGCCCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_022739_1

>merge|NC_022739|1|292120-292232|CRISPRCasFinder
GACGCTGCACCTGTTCAAGCCAGCCAGCCCGTGGCGGCCGCAGCGCTGACCAGCGCCGAGGCACAGGCACCAATCCGTCAGGACGCTGCACCTGTACAAGCCAGCCAGCCCGT

>NC_022739|1|1|292120-292232|CRISPRCasFinder
GACGCTGCACCTGTTCAAGCCAGCCAGCCCGT	GGCGGCCGCAGCGCTGACCAGCGCCGAGGCACAGGCACCAATCCGTCAG
GACGCTGCACCTGTACAAGCCAGCCAGCCCGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_022739.1\|WP_023383804.1\|299642_300650_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237846
NC_022739.1\|WP_023383800.1\|295378_295810_-\|lytic-transglycosylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|381603
NC_022739.1\|WP_175442732.1\|297646_298831_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237072
NC_022739.1\|WP_023383799.1\|295099_295378_-\|hypothetical-protein	unknown	unknown	unknown
NC_022739.1\|WP_041925801.1\|282433_284866_+\|type-IV-secretion-system-protein-TraC	unknown	unknown	gnl\|CDD\|274279
NC_022739.1\|WP_023383803.1\|299076_299493_+\|hypothetical-protein	unknown	unknown	unknown
NC_022739.1\|WP_023383790.1\|281970_282321_+\|hypothetical-protein	unknown	unknown	unknown
NC_022739.1\|WP_023383786.1\|278648_279281_+\|sex-pilus-assembly-protein	unknown	unknown	gnl\|CDD\|377500
NC_022739.1\|WP_175442735.1\|293455_295096_-\|Flp-pilus-assembly-complex-ATPase-component-TadA	unknown	unknown	gnl\|CDD\|225363
NC_022739.1\|WP_041925800.1\|279277_280123_+\|type-F-conjugative-transfer-system-secretin-TraK	unknown	unknown	gnl\|CDD\|368991
NC_022739.1\|WP_041925804.1\|302561_303026_+\|membrane-protein	unknown	unknown	gnl\|CDD\|225675
NC_022739.1\|WP_082426438.1\|300701_302255_+\|conjugal-transfer-protein-TraN	unknown	unknown	gnl\|CDD\|237072
NC_022739.1\|WP_084212978.1\|281342_281951_+\|type-IV-conjugative-transfer-system-lipoprotein-TraV	unknown	unknown	gnl\|CDD\|370611
NC_022739.1\|WP_023383797.1\|292929_293523_-\|thiol:disulfide-interchange-protein-DsbA/DsbL	unknown	unknown	gnl\|CDD\|239317
NC_022739.1\|WP_082412208.1\|286108_287080_+\|conjugal-transfer-protein-TraF	unknown	unknown	gnl\|CDD\|372692
NC_022739.1\|WP_023383792.1\|285046_285511_+\|hypothetical-protein	unknown	unknown	unknown
NC_022739.1\|WP_023383795.1\|287079_288531_+\|conjugal-transfer-protein-TraH	unknown	unknown	gnl\|CDD\|368759
NC_022739.1\|WP_023383788.1\|280125_281328_+\|TraB/VirB10-family-protein	unknown	unknown	gnl\|CDD\|319756
NC_022739.1\|WP_041925802.1\|285515_286079_+\|S26-family-signal-peptidase	unknown	unknown	gnl\|CDD\|274044
NC_022739.1\|WP_023383801.1\|295858_296821_+\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|276807

Protein	Function_ID	Function_description	E-value
NC_022739.1\|WP_023383800.1\|295378_295810_-\|lytic-transglycosylase-domain-containing-protein	gnl\|CDD\|381603	cd13400, LT_IagB-like, Escherichia coli invasion protein IagB and similar proteins. Lytic transglycosylase-like protein, similar to Escherichia coli invasion protein IagB. IagB is encoded within a pathogenicity island in Salmonella enterica and has been shown to degrade polymeric peptidoglycan. IagB-like invasion proteins are implicated in the invasion of eukaryotic host cells by bacteria. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Members of this family resemble the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.	5.14327e-46
NC_022739.1\|WP_175442732.1\|297646_298831_+\|hypothetical-protein	gnl\|CDD\|237072	PRK12355, PRK12355, type-F conjugative transfer system mating-pair stabilization protein TraN.	2.02398e-05
NC_022739.1\|WP_023383804.1\|299642_300650_+\|hypothetical-protein	gnl\|CDD\|237846	PRK14876, PRK14876, conjugal transfer mating pair stabilization protein TraN; Provisional.	3.96713e-06
NC_022739.1\|WP_041925801.1\|282433_284866_+\|type-IV-secretion-system-protein-TraC	gnl\|CDD\|274279	TIGR02746, hypothetical_protein, type-IV secretion system protein TraC. The protein family described here is common among the F, P and I-like type IV secretion systems. Gene symbols include TraC (F-type), TrbE/VirB4 (P-type) and TraU (I-type). The protein conyains the Walker A and B motifs and so is a putative nucleotide triphosphatase.	0
NC_022739.1\|WP_175442735.1\|293455_295096_-\|Flp-pilus-assembly-complex-ATPase-component-TadA	gnl\|CDD\|225363	COG2804, PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion].	1.19092e-112
NC_022739.1\|WP_023383786.1\|278648_279281_+\|sex-pilus-assembly-protein	gnl\|CDD\|377500	pfam05309, TraE, TraE protein. This family consists of several bacterial sex pilus assembly and synthesis proteins (TraE). Conjugal transfer of plasmids from donor to recipient cells is a complex process in which a cell-to-cell contact plays a key role. Many genes encoded by self-transmissible plasmids are required for various processes of conjugation, including pilus formation, stabilisation of mating pairs, conjugative DNA metabolism, surface exclusion and regulation of transfer gene expression. The exact function of the TraE protein is unknown.	2.57686e-29
NC_022739.1\|WP_041925800.1\|279277_280123_+\|type-F-conjugative-transfer-system-secretin-TraK	gnl\|CDD\|368991	pfam06586, TraK, TraK protein. This family consists of several TraK proteins from Escherichia coli, Salmonella typhi and Salmonella typhimurium. TraK is known to be essential for pilus assembly but its exact role in this process is unknown.	1.48833e-16
NC_022739.1\|WP_041925804.1\|302561_303026_+\|membrane-protein	gnl\|CDD\|225675	COG3133, SlyB, Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane].	3.58794e-18
NC_022739.1\|WP_082426438.1\|300701_302255_+\|conjugal-transfer-protein-TraN	gnl\|CDD\|237072	PRK12355, PRK12355, type-F conjugative transfer system mating-pair stabilization protein TraN.	1.17067e-51
NC_022739.1\|WP_084212978.1\|281342_281951_+\|type-IV-conjugative-transfer-system-lipoprotein-TraV	gnl\|CDD\|370611	pfam09676, TraV, Type IV conjugative transfer system lipoprotein (TraV). This entry includes TraV, which is a component of conjugative type IV secretion system. TraV is an outer membrane lipoprotein that is believed to interact with the secretin TraK. The alignment contains three conserved cysteines in the N-terminal half.	4.02779e-26
NC_022739.1\|WP_082412208.1\|286108_287080_+\|conjugal-transfer-protein-TraF	gnl\|CDD\|372692	pfam13728, TraF, F plasmid transfer operon protein. TraF protein undergoes proteolytic processing associated with export. The 19 amino acids at the amino terminus of the polypeptides appear to constitute a typical membrane leader peptide - not included in this family, while the remainder of the molecule is predicted to be primarily hydrophilic in character. F plasmid TraF and TraH are required for F pilus assembly and F plasmid transfer, and they are both localized to the outer membrane in the presence of the complete F transfer region, especially TraV, the putative anchor.	3.20559e-80
NC_022739.1\|WP_023383797.1\|292929_293523_-\|thiol:disulfide-interchange-protein-DsbA/DsbL	gnl\|CDD\|239317	cd03019, DsbA_DsbA, DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol oxidant known, due to the unusual stability of the thiolate anion form of the first cysteine in the CXXC motif. The highly unstable oxidized form of DsbA directly donates disulfide bonds to reduced proteins secreted into the bacterial periplasm. This rapid and unidirectional process helps to catalyze the folding of newly-synthesized polypeptides. To regain catalytic activity, reduced DsbA is then reoxidized by the membrane protein DsbB, which generates its disulfides from oxidized quinones, which in turn are reoxidized by the electron transport chain.	1.07313e-39
NC_022739.1\|WP_023383795.1\|287079_288531_+\|conjugal-transfer-protein-TraH	gnl\|CDD\|368759	pfam06122, TraH, Conjugative relaxosome accessory transposon protein. The TraH protein is thought to be a relaxosome accessory component, also necessary for transfer but not for H-pilus synthesis within the conjugative transposon.	4.08202e-82
NC_022739.1\|WP_023383788.1\|280125_281328_+\|TraB/VirB10-family-protein	gnl\|CDD\|319756	cd16430, TraB, TraB is a homolog of VirB10 which forms part of core complex in Type IV secretion system (T4SS). This family contains TraB (VirB10 homolog) and a component of the type IV secretion system (T4SS), and similar proteins. T4S system is employed by pathogenic bacteria to export virulence DNAs and/or proteins directly from the bacterial cytoplasm into the host cell. It forms a large multiprotein complex consisting of 12 proteins termed VirB1-11 and VirD4. VirB10, interacts with VirB7 and VirB9, forming the membrane-spanning 'core complex' (CC), around which all other components assemble. The CC is inserted in both the outer and inner membranes, playing a fundamental role as a scaffold for the rest of the T4SS components and actively participating in T4S substrate transfer through the bacterial envelope via conformational changes regulating channel opening and closing. TraB is localized similarly to related proteins in other systems, but unlike in other systems, Neisseria gonorrhoeae TraB does not require the presence of other T4SS components for proper localization. It has been shown to be expressed with TraK (VirB9 homolog) at low levels in wild-type cells, suggesting that gonococcal T4SS may be present in single copy per cell and the small amounts of these proteins are sufficient for DNA secretion.	2.34234e-102
NC_022739.1\|WP_041925802.1\|285515_286079_+\|S26-family-signal-peptidase	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.64952e-15
NC_022739.1\|WP_023383801.1\|295858_296821_+\|sel1-repeat-family-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	5.41108e-15

>NC_022739.1|WP_023383795.1|287079_288531_+|conjugal-transfer-protein-TraH
MRNILKQLVSLLLVATLTMVSAPASAGLADALDGMFMSNSTSAGAFTSQSRGGMVGGGAALRSPVRNINLVAFDPPRFSAGCGGIDMFAGSFSFINADALVALFRQIAANAVGVAFKAAIDAINPALGKLMQDFQNKLQALNQMMKNTCAVANSIVKSFTDPSARKEMVDQASTAASAATGSFSDLFAGLTDLFSSPNSSSDKGTNDGSCEECGNPVWKALTDTSSGQYLGNPDTGEADSNLANEVVMSMIGAVVMTAPDSSSKNSDGSEKPKVGQIYSPTLTLMNFKNGSSSNSTPLKLLHCDNGYDRNKCTSINPNKTLSFDGTLGYTNKMLFGYAQGATSGTASTSIVGKLTNCTSNSCDFTAAQKQFINSVKTPALALIRKVQQFPGAIQGVAEQMAPIIANELALKYGEAALYAANQTFNGVKGIKPDFVDQNINKLVQELAAIRAEDANFQPRVVATEQWIKMILTSNPAIFVKPGL
>NC_022739.1|WP_082412208.1|286108_287080_+|conjugal-transfer-protein-TraF
MRTREGLLKNILVSALLSIAALPSVVYADVDSGSPRFIERKAEGWFFYKDPKETAPPPPLIRQEPKAPSEKPDSKEPTVHPFSVSWLRENMPKLLDAAIDDPSKENVEAYLYAQRVAMDKSQRYAEMTTRVVAADPFLDENNRVPIATYTKPFFLRNAQAGVTEALKHVATVGGLWVFFDSKCEFCRPQVNTVQKLAKEYGFVTKFISMDGKPLPNVTEFEKNTGQASILNLRITPTTVLVVPPNNYYIVSQGMMAQDQLAERIIIAADSNNLLPKDIAQKINTYDRGVLTNEDTQKGASDDPKQWVKYLKDKLEGRYEGGQQ
>NC_022739.1|WP_041925802.1|285515_286079_+|S26-family-signal-peptidase
MNSKALASRLVSPLKTLRTDKARLRFLRNSLIGIAAAFIVAIAAVTTFRQDYRIGVDLASVRCLPWRLYMITYGQPADLKRGDFVAFVPKGGLMGEHFEGKTVGKMVAGLPGDKLVVKNNVAYIGDRLIGELDLIEKLGKKSGDFDRVMTVPAGKILVIGTEPRSYDGRYWGFLDSKLIIGKVGPII
>NC_022739.1|WP_023383792.1|285046_285511_+|hypothetical-protein
MTDTANSQQQQPGEQIRPDDDQVRTKPAQGGKAQQAPAGVSFLTCAFVALAVSGFTSFMAYHFAGQNLSSGAQVVLVDGTKLANAQMKRTLDKAGLSPEQAQADGLAFVTELQNVLKGYTDSGVLVINSSVALNAPAGLNVTGQVAQHLGLELE
>NC_022739.1|WP_041925801.1|282433_284866_+|type-IV-secretion-system-protein-TraC
MAASKATIKGDRTSTPQQKLNVRAIDPDSKVFFCSDGNEHYLGACFVSDALTGASSSTVDKLQSALSMNFAPGTFIQIAMLGSPDVGEYIDAYLNSKPALNPILKALSRQHADLINGGVDDPLVQRSGVMLNRQRVIVTVKFPCRNESPDDADIAATKESADRVTEALKAASLNLFQLDAMGYLVLMRIITKLWDAPRSHYDEDQLIKDQIYYPGDSINYDDPSTINFNDGGHYAKALSVKHFPQKTSLAIMNHMIGDPNGLSNQITDPYYMVLTIHYPDQVVKKDEVKQTSSIINHQVFGPTAHLIPILSYKKKGIDTLVHEIDGKGAIIVEVNFTIFLFSRDKQRLNKLSAGLQAYYTSLAFELREDRRILEALWNNLLPLNTSREGVKNLYRFHTMAVRHACQFLPILGEWTGSGMAGAMLMLTRRGQAALIDLYESSTNYSGIIFAEAGAGKSFFTQKIAADYLAAGAKLWVIDAGRSYLKLCKMVGGEFIEFKPESDVCLNPFTHVEDLHEEMDILKATIAKMAAPEDTLNDYQLSRVEQAITSTWEKFGNAANITAVADWFINQSDDEECRRLGRQLFPFAGGQYTKWFDGENNLDMSNAFICMELSDLKGRPALQQVVLLQLISRINHDMYKAQLGERGRKKILIVDEAWEMLDDPMMAKAMVAAYRKARKEDGAVLVVTQAIGDVYASKNTEAIAANSAWQFILQQKSESIDSAIDSKQFKIEPYGAHMLKTVHTMPGKYSEIMVKRSETDWGIVRLVVDEFHNVTFSSKGAARNEILDDLDRGVDAVEAVNNYMARQSSAA
>NC_022739.1|WP_023383790.1|281970_282321_+|hypothetical-protein
MTAQIAQIAQIETNAVAAAPFKKIDKRALVSMAVIGLAVAVDVTAGADSTFNEIVTSLDGWMTGSLGKVFALGALGTGLAIGVVKQSVMAVVTGVAVALSASVGPGVLTNIFTATL
>NC_022739.1|WP_084212978.1|281342_281951_+|type-IV-conjugative-transfer-system-lipoprotein-TraV
MKRTALVAALLPIALLSGCSSWLNTAGEDEFSCPGMPQGIICKSPMAVYKSTEQSPALTDSDMPIGQKAPNVKYGDDMGKTAGSEHNLKVSNGVPGPTVAELARPVRVPAQVMRIWIAPWIDSKDDLHFPSYLFTEIQPRTWSFGKSEYSGQGMVVPHLELTAVPPVNVAAPKSENVAAEPTNYGPQVTSSAIPSTTDINLN
>NC_022739.1|WP_023383788.1|280125_281328_+|TraB/VirB10-family-protein
MAIKDQLKDKWQDLSPGVRSTVAIVGLLGFLMIVGSVIIGNDKPKNNSKTDATSDTKLLLPRGDNNTPEQIMAMMAVQNKRLDEFSRSIKQMDQDRKDDRLRALEEERLRGQRPDPVTQDTLRELKRLGDRMEKLELSKGATAPALNSALPGYESATGTGEALQEPKPKAATLRVTGGTQTARNEAPKQAEKPTPAMPAGSFFEGVLLNGMDAPTSATTQKNPVPTTMRIKSDAVLPNKYNVDVKECFVLASGFGVLSSERAMLRTETFSCVRKDGKIIEGKMEGYIVGEDGRVGMRGRLVSKQGQMIAKTLVAGGLSGLAQGMTPQTIPQLSLGDSSTTQTQSADTSTILQTGVAKGFSTSANEIAKFYMEMAREMTPVVEIDAGRKVTIMLVKGVELK
>NC_022739.1|WP_041925800.1|279277_280123_+|type-F-conjugative-transfer-system-secretin-TraK
MKRSAIALIVLATIHASISWADGMAEVKLPPVPTAAKRVKPVEAQPLPGLGVMPGAESDSRTQVVRVSSDRNEVIYVSNILPNRISTPFASPKAVDQQPDDLDISQIGQSLYATMKTKDKPVALYVTGSNPNDPVISLTLIPKELPQQTITLQLDKPMAETGGHASENHAPDSNNYTDTIRYVLREAALGKTPEGFSEGLLPASAANIGNVIAYPKVRYSGPEYDIYRYRLQGTSKTDVDLDEGTFYSEGVRAVSFFPTATLRAGMTTDVFIVSDKSATGN
>NC_022739.1|WP_023383786.1|278648_279281_+|sex-pilus-assembly-protein
MKIKKMQNTMEGLKSLRNFQTLSIACLSVSVLLLTFNQMGQHETTRLVPPNLDKAVKVGWNNADDEYIKSFGLYASTLMGNVTPKNVNFIADSVSAFVDPKIYADVRKKMFVLANDPVFATNAGSVSWNATDISYEKETKKVFILGSMESRSATGKPKPDYQVVEYVIEMRAGRPWITGMDHYPGSTPKTLKWLQSHPPKPAEPTKEALQ
>NC_022739.1|WP_023383797.1|292929_293523_-|thiol:disulfide-interchange-protein-DsbA/DsbL
MAALLATPVLSLAQESLPSLPYREVAAQAEDSHKVIVFFSFACPVCASYDQTLARWAKTMPPGWSAEFLPVAVPDKANYIAARAFFAVQDADPARLDAFMSAAYTLIQQNGMPMESPDTWTKAVAISNVQGFNEAWHNVTQQRLEKAFAKLLTYGVDATPSMVINGKYVITPDDVSGDSALYMNLANGMISKVMLEQ
>NC_022739.1|WP_175442735.1|293455_295096_-|Flp-pilus-assembly-complex-ATPase-component-TadA
MTVAKEPDLFIYNSPADKPAATYLNDLFRMAAENKVPDIHFQWVQGHVHIQLRQDGQLRHFETVEPAMGKMIDTKIRSRATMDLSQHQIPLDGRIGLRYPGLELEVRVSLVPSHNGQKIVCRLLDQENASMSLDRIRMPPLVEHAFREMINEPQGLILVTGPTGSGKTTTLYAALNAINDGTLNICTIEHPVEYVVKGFVQINVTPQLSFALGLRALLRQDPDVILIGEIRDQETAQIAIQAANTGHLVFATLHSNSAAQAVPRIVDLGVDAQTLASVLIGVIAQRLVQTLRTDIEHEWLPINDVERMWLKKNGLPPVTGNIPFAPSKDSFSGKCPIIELIRSDRSVRAAIIGGGGEMAVLNAAARQSQFDTLGQSAVRMVTDGLTTLGRVRTLIKDDSVKPAVRRIGDVLIAQGLITFTQANQAAELQLRCTIEGKVKKFGQALIDLALVSQDDVVNALGYTEGAVEFLNELAATRKINFRALKDTVELWRTERNQESIFDMLIEQNLISKESLYEEVYCADGYGSPAGNSSPLLSTGVAAVAAV
>NC_022739.1|WP_023383799.1|295099_295378_-|hypothetical-protein
MKQLFSSFFAVLLFGWILYTVSPEEPCERVERGALPVRVVFDAVRWAGTNYLSTDSRIDLLIWSIAADKSVQSFISRLFYGPELNCTTGQAK
>NC_022739.1|WP_023383800.1|295378_295810_-|lytic-transglycosylase-domain-containing-protein
MKKLSLPFLLIGALAWLPTTSHADCFAEAAARYRVSEKLLRAIQVTENRPGKADVVSQKNSDGTWDIGLMQINSSWLPKLSKYGIGEKELLDRCVSANVGAWILASNIASHGHVWKAVGAYNSPNEKSQRIYIQKVMNNYGGL
>NC_022739.1|WP_023383801.1|295858_296821_+|sel1-repeat-family-protein
MHSLNRLPILLALPLAFVSLTCAASSAQDTSAAAYFSNEAAAGGADLPDISTAMKGLLSTAREGGEVLRTWAAYKAGDKAALPKLFELAQGGNSRAQNVVGYLLDHGEGVKKDSAAAAAYFSAASSDYPLARYNLAVLTLLGRGVPKDETKAMEMFESSVKDASVDLAAVRLSLYYLNKGDHDKAWTWANEGANRGNVTAYYLLGRMLYERGGYQEAYNWLTKAAQASEPNAPAILSAMYKNGQGMNQNVKMAASWWMIYVGLNKGKPGMNSAGMSSFGLTAKEQNDATSFATNWLLTHKHMKRPDYDATLLQANRNDKS
>NC_022739.1|WP_175442732.1|297646_298831_+|hypothetical-protein
MKKGKQRVLTLAGLLAVAVGALADPHSEGTELGKSTLGKLSSNVTSANAKSMPFYTDTPSQSSQFGSSSLFTVGTSRINSCKTEADGPDAIANQECDAVNFLAKNPYERVKVDVDENDPIISGIGEIINNAKPDEITESCGTKTTTTPDIYSTEVCNEYNLSDQKICSMGQVVDVDTKANFQCNVTQNALETVSCDKYLVLSCQPPIAGCTGSGIAVNSATISNGAYQFTLVGSALTIVNNVTAINEVTEADFNFSIAGLDRVDEFFINAIHSDNYVGIAVNGIFIGVHGRAFGGWNANATKLVQDTNYSPPHARWSDNPADHYKAETGNNLKTSEHIDLIPYLREGSNVINIKVLNGKGPGYGMVYITAHQQCPPECEETWVDQCSSYEQRSL
>NC_022739.1|WP_023383803.1|299076_299493_+|hypothetical-protein
MHFRAKLLSLCTSFIVLAAAPFAAHADTSKEILIEAVKSGHASAELTGDQADVWMAQTHSREPIMVEAKVVEQLKQPGCARVAIQFTQQMVPKVNGGSGPLEVGWGMNVCEDGAPPADPSLFTQEPQSATKVNKVQSK
>NC_022739.1|WP_023383804.1|299642_300650_+|hypothetical-protein
MPFYTDTPSQSSQFGSTSLFNVGTARINTCKTEPDGPDQIANQECDAVNFLAKNPYERVKVDVDENDPIISGIGEIINNAKPGDITENCGTKTTTTPDIYSTEVCNEYNLSEAKYCSMGQVVDVDTKANFQCNVTHNAIENVTCDRYLTMACEPPIVGCDNGGIVPGTTQSDMYTSWKLANSNGTYALQFGSIGDNYWRDGIYPRSLEFEVKDPTMLTEFTLASVYYDDYILIKINGTYLFSGPYGGTELSLFSNGKVNIGDGVQRNRELGKSWGAKPNINLIPYLVAGVNKLETITAVGGGGETYITMYARMLCNGPCTETWTDQCSALNARAQ
>NC_022739.1|WP_082426438.1|300701_302255_+|conjugal-transfer-protein-TraN
MVLVFFATFSHAADCRKTGETCVEGAETRNIAGNLIYKACWRYRSTYECVKPDSVDYCAAISKVAGCYQTSTSCISTAWNGTCLVEQRTYRCDNPATPKPSDTIQLDDTHTIIRDELDTSQCDPLATNPLCYIASHTCVEGPETRVINGLPVYKACWKYKDDYSCINPDKKNDCQQYEDKGCKKIDQTCIESTDPIGCVMSQITYSCITKKGETTTTEDCSTKVSCYEGVCWDTSYPSDSDFAKAVAAKEAAREAGVYGSDGELFGGEDESCRKGYGGIKNCCGKSSGAETNFSIMGQAVSTVGGGLASYGSKYMYDFAYNNVEWVKQGASALGAAAPSAPTLSFSVYGLSYAVGGTIPATGMLGGPVYGLGGGFYFDPYSFAIAVAIQVVMELKSCEPEEQQLGMHRGANLCHLVGSYCSKKVFGACLETTEAYCCYNSVLAKIINEQGKPQIGKGWGTPESPSCGGFTVEEFQQIDFSALDLSEFVDDVMNATVLPEVKNIQDDISQKASDNTYN
>NC_022739.1|WP_041925804.1|302561_303026_+|membrane-protein
MNKIIASLLIVTTAAMSGCASNMTNRDYSQATAMQKMKVELGVVDSVRDVKINGKPSPIGGMAGGALGAIAGSNGGGGLGQLAVMVVAGAVGAAIGAAVDKKAHDADGVEITVKMTSDGSLQAVTQAKDPAETFAPGDSVRLITGQTGDSRVSH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_022739_1	1.1\|292152\|49\|NC_022739\|CRISPRCasFinder	292152-292200	49	NC_022739	Pseudomonas sp. VLB120 plasmid pSTY, complete sequence	292152-292200	0	1.0

1. spacer 1.1|292152|49|NC_022739|CRISPRCasFinder matches to NC_022739 (Pseudomonas sp. VLB120 plasmid pSTY, complete sequence) position: , mismatch: 0, identity: 1.0

ggcggccgcagcgctgaccagcgccgaggcacaggcaccaatccgtcag	CRISPR spacer
ggcggccgcagcgctgaccagcgccgaggcacaggcaccaatccgtcag	Protospacer
*************************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_022738

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_022739

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection