CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_019954	Tepidanaerobacter acetatoxydans Re1, complete genome	9 crisprs	cas8b1,cas7b,cas5,cas3,cas2,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20,csa3,WYL,cas3HD,cmr6gr7,cmr4gr7,cmr5gr11,cmr3gr5,DEDDh	0	3	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_019954_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019954_1

121467-121639

TypeIII

Consensus_repeat	Method
GGTTTATAGCCTACCTATAAGGGATTGAAACTAAAT	CRISPRCasFinder

2 spacers

cas3,cas5,cas7b,cas8b1,cas6,cas2,csx1,cas10,csm3gr7

The CRISPR arrays of NC_019954_1

>merge|NC_019954|1|121467-121639|CRISPRCasFinder
GGTTTATAGCCTACCTATAAGGGATTGAAACTAAATTTAAAATCTGCCAGAAGTTCACTAAGACCCAGGTTTATAGCCTACCTATAAGGGATTGAAACAAATATTTAACTCCATTACTTAATCGATGCGGAGAGACGCGTTTTTAGCCTACCTATAAGGGCTCACATCTTCTT

>NC_019954|1|1|121467-121639|CRISPRCasFinder
GGTTTATAGCCTACCTATAAGGGATTGAAACTAAAT	TTAAAATCTGCCAGAAGTTCACTAAGACCCA
GGTTTATAGCCTACCTATAAGGGATTGAAACAAATA	TTTAACTCCATTACTTAATCGATGCGGAGAGACG
CGTTTTTAGCCTACCTATAAGGGCTCACATCTTCTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019954.2\|WP_023211308.1\|130000_130957_+\|ATP-grasp-domain-containing-protein	unknown	unknown	gnl\|CDD\|234948
NC_019954.2\|WP_013777243.1\|116907_117960_+\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_019954.2\|WP_013777245.1\|118780_121270_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_019954.2\|WP_013777251.1\|127070_128441_+\|acyclic-terpene-utilization-AtuA-family-protein	unknown	unknown	gnl\|CDD\|377804
NC_019954.2\|WP_013777248.1\|122922_124317_+\|glutamate-mutase-L	unknown	unknown	gnl\|CDD\|379405
NC_019954.2\|WP_013777256.1\|134295_135864_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	unknown
NC_019954.2\|WP_013777249.1\|124336_125791_+\|methylaspartate-mutase-subunit-E	unknown	unknown	gnl\|CDD\|377651
NC_019954.2\|WP_013777236.1\|109647_110562_+\|zinc-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238499
NC_019954.2\|WP_013777237.1\|110551_111379_+\|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224046
NC_019954.2\|WP_013777238.1\|111375_112188_+\|metal-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224033
NC_019954.2\|WP_013777255.1\|132919_134299_+\|hypothetical-protein	csx1	mkCas0112_csx1_CAS-III	unknown
NC_019954.2\|WP_013777240.1\|112616_113336_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013777252.1\|128442_128754_+\|DUF4387-domain-containing-protein	unknown	unknown	gnl\|CDD\|379559
NC_019954.2\|WP_013777242.1\|114747_116847_+\|CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_019954.2\|WP_015294800.1\|135865_136525_+\|hypothetical-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
NC_019954.2\|WP_013777239.1\|112178_112601_+\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NC_019954.2\|WP_013777244.1\|117962_118727_+\|CRISPR-associated-protein-Cas5	cas5	cd09692_cas5_CAS-I-B	gnl\|CDD\|187823
NC_019954.2\|WP_013777247.1\|122469_122892_+\|methylaspartate-mutase-subunit-S	unknown	unknown	gnl\|CDD\|179400
NC_019954.2\|WP_013777246.1\|121829_122093_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_019954.2\|WP_144312809.1\|113752_114481_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848

Protein	Function_ID	Function_description	E-value
NC_019954.2\|WP_023211308.1\|130000_130957_+\|ATP-grasp-domain-containing-protein	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	3.87702e-54
NC_019954.2\|WP_013777243.1\|116907_117960_+\|type-I-CRISPR-associated-protein-Cas7	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.25218e-49
NC_019954.2\|WP_013777245.1\|118780_121270_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.31671e-47
NC_019954.2\|WP_013777248.1\|122922_124317_+\|glutamate-mutase-L	gnl\|CDD\|379405	pfam13941, MutL, MutL protein. This small family includes, GlmL/MutL from Clostridium tetanomorphum and Clostridium cochlearium. GlmL is located between the genes for the two subunits, epsilon (GlmE) and sigma (GlmS), of the coenzyme-B12-dependent glutamate mutase (methylaspartate mutase), the first enzyme in a pathway of glutamate fermentation. Members shows significant sequence similarity to the hydantoinase branch of the hydantoinase/oxoprolinase family.	0
NC_019954.2\|WP_013777249.1\|124336_125791_+\|methylaspartate-mutase-subunit-E	gnl\|CDD\|377651	pfam06368, Met_asp_mut_E, Methylaspartate mutase E chain (MutE). This family consists of several methylaspartate mutase E chain proteins (EC:5.4.99.1). Glutamate mutase catalyzes the first step in the fermentation of glutamate by Clostridium tetanomorphum. This is an unusual isomerisation in which L-glutamate is converted to threo-beta-methyl L-aspartate.	0
NC_019954.2\|WP_013777236.1\|109647_110562_+\|zinc-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	1.41761e-99
NC_019954.2\|WP_013777237.1\|110551_111379_+\|metal-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	3.20401e-88
NC_019954.2\|WP_013777238.1\|111375_112188_+\|metal-ABC-transporter-permease	gnl\|CDD\|224033	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism].	4.23123e-58
NC_019954.2\|WP_013777239.1\|112178_112601_+\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	2.79885e-45
NC_019954.2\|WP_013777252.1\|128442_128754_+\|DUF4387-domain-containing-protein	gnl\|CDD\|379559	pfam14330, DUF4387, Domain of unknown function (DUF4387). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are approximately 110 amino acids in length. There is a conserved RSKN sequence motif.	2.00683e-57
NC_019954.2\|WP_013777242.1\|114747_116847_+\|CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.87566e-42
NC_019954.2\|WP_015294800.1\|135865_136525_+\|hypothetical-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.92224e-11
NC_019954.2\|WP_013777247.1\|122469_122892_+\|methylaspartate-mutase-subunit-S	gnl\|CDD\|179400	PRK02261, PRK02261, methylaspartate mutase subunit S; Provisional.	3.48999e-86
NC_019954.2\|WP_013777244.1\|117962_118727_+\|CRISPR-associated-protein-Cas5	gnl\|CDD\|187823	cd09692, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.53955e-18
NC_019954.2\|WP_013777251.1\|127070_128441_+\|acyclic-terpene-utilization-AtuA-family-protein	gnl\|CDD\|377804	pfam07287, AtuA, Acyclic terpene utilisation family protein AtuA. This family consists of several bacterial and plant proteins of around 400 residues in length. One member of this family has been characterized in Pseudomonas citronellolis as AtuA, a member of a gene cluster that is essential for the acyclic terpene utilisation (Atu) pathway.	1.34325e-17
NC_019954.2\|WP_013777246.1\|121829_122093_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.91101e-32
NC_019954.2\|WP_144312809.1\|113752_114481_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	2.74471e-36

>NC_019954.2|WP_013777245.1|118780_121270_+|CRISPR-associated-helicase/endonuclease-Cas3
MQYLAHYDKGKQEKQFLNEHLTSVATLAKTRVLPCVVFDDLDSSKIEEICYWTGYFHDLGKYSIYFQDYLQKGISSPLKNHAHISACFAYSYLSNKATSRFDSDKTLLFFIYTCIRLHHTSLKCKGLFNYGIWEDLIPISKNISDKSNEIIKDLGLAQDMSDEEFRALIDIEKFKANAFSLERIPLMFNNSRISNPKWYFLLIYLFSMLIDTDKLDSANIKSEKISTVPPENVTSYIFSKHGKKSDTELINNREKARKSMIEVVESLSNDALKNVRFFTITAPTGIGKTLSSLQCALDLQQKIAETEGYTPRIITAIPFINIIEQNKLEYENVMGKECKIAVHHRLSDFGVAKSKDETIPVDRVLLETESWEADVILTTFVQLFQSLFSSTNKMLKKINKLAGSIVILDEIQAIPEKYMPLIGASLQMIAKYYGTRFILMTATQPKILQFGSMLLQYTEKNSKQIESIELLPNHEEYFKCLTRTKFVPLLENVLDTEDFLDVFFNKWDYTKSCLIVVNTIKRSIDVYKKIKEELALRGFKLPVYYLSTNIIPLKRRDVIQEVKDLLESEQPVILVSTQTIEAGVDLDFDMAFRDFAPLDSLVQTAGRVNRQGKKGNYSPVYIIQLENDSHYIYDLSLREVTINLLKELLTAQEEIKETDYVSLTKRYYDLILKEGVDDASKRIWNDGILKLDFDKLEEFKLIESPGEVYDVFIEKELSATNLADAYEQVLGYKDSFDYDLSKIFPDFKSDQFEKTLNVFQRKALLRLIMAKMHDYIIQVRVSRLKENRPVEFKERGNIESSLYWVPPTKCDDYYDEDTGFKDESGDGFI
>NC_019954.2|WP_013777244.1|117962_118727_+|CRISPR-associated-protein-Cas5
MKVISFHLKGKMAHFRKFYSNASALSYFVPPRTTICGIIAGLLGLERDGYYDDFSLDNCKITITSCSPLKKTMQKLNYLMIKSVQDLNGSQENHSQTATELVIPQDIRSGYIDYKIWFHHCDNKIMSDVESIINDCSPFYESKWSCVALGSAFNLGWIEKGEILEAEEKFVKSKKLVSSSIPIHNIEEIKVDEINTNKVYKLIKEEVPLEFDQQRRITKEGLKEILINVNGDYIPAVVDSFVSLDNGEVITWLE
>NC_019954.2|WP_013777243.1|116907_117960_+|type-I-CRISPR-associated-protein-Cas7
MLINQNSDFLFGFQATMSNPNGDPDQENKPRMDYETSTALVSDARRKRDVRDFLKNKGYKIFVDTLADQKVPMDKMLEYITDTFLENSGNIELLFKENPNLKVQWEKVFGTTENPNKEYNEKKEKLKKNKDFIRLNNIFLTEIIKKELIDIRLFGSAMAVEGVSKTFTGPVQLNWGYSLHPVELIKSNTITSIMNEDNSTFGKKYKLYYALMAHYGTINKYNAKLTGMTEKDRELFRKALGQSLMANQTDSKQGQEPIFYLEILYAPEFDGYLGDLRRFLNVEYATYAIRSLDDIKVDFSRLNDAINNVKNKGYIDKVIGWVNPFIPNESFMNLPEFENIDLLAPIKTEE
>NC_019954.2|WP_013777242.1|114747_116847_+|CRISPR-associated-protein
MSIPKLTALIGESASERFQDEFTPLMKSIKKVKDDETPYIVFLVMDLAKEEIYFKLNKKLTEDSVNEYYYFGNNSGSGAQYYLTRDSKSLRYLLTRTFNELYISLSKNDLENGELAKLIKKMEEKKLVKLGKKQGENCFNLEKLSLAKSGKVKDIKLGRGKSDVNDIYLEGKRYHPEDFIRIFLQDANKKNKFVLIVPKVITEDGHEIILSTHDEYLELVRRENKLGSNQNLTKDSNKNKRICYICKKEGPDVSSEYSKKFSRTGINKIFTTTTINTSPFLKKSDYDKVYSICIDCYQKLKAGEKVISMDFRSKIAGEDVFIIPQGLLGDFDYNYLGILKKDVDLAFKSSDAKEWFETIKSEQDLSGVRQYLVNFIIYRTDGTSLTVLETIEDVPMLRLEKIMEIFANITNELKPHIKNFSLGSVYRLIPVKVNDKGKQIDVGRVLSLYKAILSGEKISSRTLFDYALEGLEKGIKQLEKATINNYYNMGLTRYLNGYEDFFIKRLIFGYIVLFKACQELNLLDREVFKFQKEEEDDFMDNFETPSKEVNALIRRIEEFLKRQGFNNNAKAMFYLGVLVNRVAMAQMEKEHKKKPILKKIQFQGMNAKEVYGLYQDVVEKLIQYNKMTLFTEAIMNRFHYYYGSLDGDWKLDDRANVFYIMAGYSYMVGNKALDFTKEEEEAEIGVGDEEEVSEDRIEE
>NC_019954.2|WP_144312809.1|113752_114481_+|CRISPR-associated-endoribonuclease-Cas6
MYFWPENGQYLTLPIHYNHIVQAVIYDSLDEDISNFLHEKGFSYEKRSFKMFAFSRLMGTYEIDKGKEKIILQKPVSLVVTSPYRNFCTSLANGLLLKSTVRLGNTNMQVTNVSFAKDMIYQDKIQISTLSPIVVYSTLMRPDGRKYTCYFEPGEKDFDEIMEKNLRKKYIAFHKTEPPEGNVKLEPLRQPKLSIIKYKNTIIKGYSGRFILSGPAPLLQIAVESGLGSKNSQGFGCVEVEG
>NC_019954.2|WP_013777240.1|112616_113336_+|hypothetical-protein
MNRLIKRLLILMLVTILILAGCAKENDSKPVVSQPPDTSSVGNENEPVPNQAASPDENIGDTNSNLTDENADSETMFKVQDSKQIQGWKELIVKDYAYTTEDWESYSFRENSPIISYSLNFPGNWNVDYSIFTDENGAKVAELLPTIIMKEGQSLLDNWEPNSECELISRENIKVGDLTGVKIILKSYPYGGDIEMWYPHTYYLTDGKQVFIMSFYALELDSEEQELFDKIIKTFQFLS
>NC_019954.2|WP_013777239.1|112178_112601_+|transcriptional-repressor
MDVEELLKKQRLKVTPQRKAIINVLESSDGVLSAQDIFTEVIKILPNINFSTIYRNLDLLLERGILCRITPESGGILYELRREEGHHHHVICKKCGASIPLDYCPMGNIEKELSRKGFTPTEHRFEIYGYCNKCSKKIKE
>NC_019954.2|WP_013777238.1|111375_112188_+|metal-ABC-transporter-permease
MMYILSFDFMQRAFMAGIITALLASVMGVFIVLRRMSMVGDSLSHAALAGVAGGMLVGIYPFYGALIFSGAAAVLIEIIRSAFSKYAEVALAVVLSGGMGLAVVFISIGKSFNADLMSYLFGSLVAVSSQDLLLIAILGFIIMFSMILLYRELFSITFDEEAARLSGIPVKAVNMYFTLMTALVVALSIRVVGALLISALMVIPAAVGMQLAKSFKSTFIIAVGVAIFSVVSGLYTSFIFDLAPGGTIVLIATAILMIVLCVKGAVKQWM
>NC_019954.2|WP_013777237.1|110551_111379_+|metal-ABC-transporter-ATP-binding-protein
MSSNSLCAGFGRVYDGEAGDDMEDIIDTSKIKDNEVISLKNVDFSYNGTLVLTNINITVEKGDFIAILGPNGSSKSTLLKIMLGLLTPKAGEVKIFGQNVRHFKEWSKIGYISQQAANTNTSFPATVEEIVSSGYYTGFGRLFDKAERKAATGEALAAVKITDLSNRLIGQLSGGQRQKVFLARALVKKPEALFLDEPTTGIDAVSQQEFYEMLAKLHKNRMTIVMITHDIDAAIKRATKVGYMEDGNINIYENNGNLSGILASRLIGEGARGRI
>NC_019954.2|WP_013777236.1|109647_110562_+|zinc-ABC-transporter-substrate-binding-protein
MKIAKSFLVLLLILSISVLTTACSNNSQVVLPNQPNDQQNSLKIYTTFYPLYDFTKKIVGDNAQVENLMPAGVEPHDFEPSPKQTAMIYDGDIFIFLGESMELWAKKMAGDLDKKGVAVVEAGKGLIENNDPHIWLDPVMAKEMAQKIFDGVVAKDPEHSEVYQENLNNLMQKFDELDKNLNEIISSSSEKNIVTSHSFLGYVARRYGLEQTAITGLSPQEEPSPKKMAELVEFCKAKKIKYILDEPGEVSKLSQTLADEIGAEILIINPLGTLQPNEVKAGEDYFSVMEKNLEVLKRVLSYEQ
>NC_019954.2|WP_013777246.1|121829_122093_+|CRISPR-associated-endonuclease-Cas2
MFIILVYDVGEKRVAKVLKICRKYLTWVQNSVLEGEISAANFKKLKLELKRVIDEDEDSVIFYILRTTKYSERQSMGIKKGGDELFI
>NC_019954.2|WP_013777247.1|122469_122892_+|methylaspartate-mutase-subunit-S
MKYDDKKTIVLGVIGSDVHSVGIRILDEAFSEAGFNVVNIGVLSSQEDFINAAIETDADAILVSSLYGHGELDCKGFKEKCVEAGLGDVILYVGGNLVVGKQDWPATEKKFLDMGFDRVYPPGTLPEIPINDLKNDLGIK
>NC_019954.2|WP_013777248.1|122922_124317_+|glutamate-mutase-L
MELALLIDIGSTYTKVTAVDLETVELKARAQAATTVAEDVNIGINKALEELKAMGIDPAKAKHKLACSSAAGGLKMVAVGLVPELTTEAAKRAALGAGAKVGHVFCYELTDDELNQIARYSPDIILLAGGTDGGNKDVIIHNAEKLAELKVDAPIIVAGNKTAASAAEKALRAASKEVYVTENVMPKLECLNIEPAKKIIREVFLSKIIYAKGLSKVSNYVDSPIIPTPSAVMKAAELLAKGSDNEAGYGEVMIVDIGGATTDVDSAATGEPTKAGVTLRGLEEPFIKRTVEGDLGMRYSALALVEEVGIKNMLKNYLPCGMDEKTLQEYVKKISIDTDYVPCNETDKQIDCGIAKAATDLAVKRHVGRIETVYSPFGAAYVQHGKDLTKLDFMIATGGVLIYSENPKEILRHGLYDSSRPEVLAPENPKMLLDEKYLLSSLGLLSEIAPDKALNLAKKYLKEL
>NC_019954.2|WP_013777249.1|124336_125791_+|methylaspartate-mutase-subunit-E
MEVQNKKWDMKKFSEMRQEVLNQWPTGKEVDFEEAVRYHQNLPKNQIMTNKLREAATKNNTLIQPRAGVALLDEHIELLKFLRQKGKADVLPTTIDSYTRQNRYEEAEKGIKESEKAGRSLLNGFPAVNYGVKKCRKVIESVDCPVQVRHGTPDARLLAEITLAGGFTDFEGGGISYNVPYAKKISIEQSIYYWQYVDRLVGIYEENGISLNREPFGPLTGTLVPPCISHSIGIIEGLLAAEQGVRNITLGYGQCGNLIQDVAAVETLKELSAEYLKDYDVMLTTAFHQWMGGFPQDEAQAFGVISWGAATAALSKATKVIVKTPHEAFGVPTKEANAEGLRATRQVINMLKDQRMISSQELEKEKEIIKRETRQILSKVYELGEGDWAKGAVRAFEAGVLDVPFAPSQFNAGKILPARDNSGAVRFLNFGSIPFDDKIKEFHRRKLAERAKAENREVSFQMVIDDIYAIGQGMLVGRMDSKIA
>NC_019954.2|WP_013777251.1|127070_128441_+|acyclic-terpene-utilization-AtuA-family-protein
MEELKVLSPTAILGYGFPEESFQRGLEQHPDFIAVDAGSTDPGPYYLGAGVSFTDRQAVKRDLKLMLKAGKKLKIPVLVGTAGGSGANEHLYWTEDIIKEIAREENLELKVAVIEAQIPKEEILKKYEEGKIEPLAPAGELSREDIEETTRIVAQMGVEPIIDALENDVDLVLAGRAFDPTAFAAPCIKAGFPKGLALHMGKILECASIAATPGSGSDCMMGTLRHDCFILEALNPKRKCTVTSIAAHTLYEKDDPYRLHGPGGIINLEETEFTQIDERRVKVSGSKFIPSEEYTIKLEGAKKTGYRTISIAGTRDPIMINQIDDILEAVKDMAKNNFSNIKSDDYQILFALYGKDGVMGKLEPLKDKPSHEIGIIIEVVAKTQEMANTICSFTRSSLLHYGYPGRIATAGNLALRYSPSDIEAGEVYEFSIYHLLAVEDPKEYFPITVKTIKGSE
>NC_019954.2|WP_013777252.1|128442_128754_+|DUF4387-domain-containing-protein
MGIPITEVAEVIRSKNSGPYELTMDIIFKDFDSYENVKQKNIINKKLISSLYQIPEEDIISIINFDPAKAIKITIKRPLVAGAVGESDVYGAQQHAPLLGIEV
>NC_019954.2|WP_023211308.1|130000_130957_+|ATP-grasp-domain-containing-protein
MKIAILIDEPRVSYLPGEEGLNEDLQKRKTVKNLKEVLSKRFECSLVKADSDIISKLQNENVSLVFNLCNGIRGETRQAQIPAILEFSGIPYTGSSILGHTLAINKNYACKVFKGSGVTTPEFISIYDKDDLMQLRNKEIKFPVLVKPCDEGSGRGIHQDSLVYDFRSLKRKVQQELRLYNPPIMVTEYIKGREFTVGILGNGNNLKVLPILEISFEALPDDLAKFYSFEVKANYADKTIFRCPAPLDNKLKTKIENTAKKAYNALSLRDYARVDVRVKDDTPYVLEVNSLPGLQKGYSDITKMASACNLAMKALSLK
>NC_019954.2|WP_013777255.1|132919_134299_+|hypothetical-protein
MDIFTSFTDLVLLVGTNPLPNYIVIKYFLKHNEKLKRIWLIYSEETNVQAGTEELAENITSVIKKEFLSNKPDLKFKHMPLSDVGSASTILDELQRNMKIEVSSPNIFHLNYTGGTKSMAVQTYKYFLENFGKRCTFSYLDGRDFKLKGDQSSAHVTKDLRYEIGISVESLFELHGYEKKGGQNNPSYPDTVKKFEEIIRLGKLNEYLSWKKSTIREFFYEGSNCIKKKNRFLTHNNIYSDEDVKRFKQNFKDKMTDEIILELLKSIPKENSILDENGDIWVPDKSTTNKEYKERVGDSVENFLDGKWLEVYVYNVICQKIKQNEKLNELYKKGQLIIDNNYEIKKKNTEKKHFEIDVILLNGYQVCGISCTTASDDSTCKNKGFEIIHRARQMGGEEAKSILIACLEDKESRSIEDFYEDLKDTSGSRTHEFMVLGLKDLTPEKLWEKIYEHIWGADL
>NC_019954.2|WP_013777256.1|134295_135864_+|hypothetical-protein
MSKVTAILADTVSIQKYVYSSNRLKENIGASSIIANIYKESLANTLEKTLEHGVSLDEWEKQPETIAIKNSNTDFEVGYIGGGNALLFFNNEATAKEFISEWTRSLLLEAPSLNVAFAISEFNIDNFQNEMKNLFKQLEINKSKYFPQTFLPKHGITADCPYSGLSAEVYKPGTNDEKGAYISSASYVKYKHIDIDDAKVEVERISNGKFSLTTNIEKLGQTKGQNHIAIVHIDGNSMAEHFKSCENLVAIRKLSKRLKDIMQSVYEEFLNYIFEQMDLLLSDESGFNIQLENGKYIIPFRPILREGDDITFITDGRLGIPFAQKYLELMSDKTLYNENKLSACAGVAIIKTKYPFFRGYNLTEELCQSAKREARENKGTSWLDFHISYGGFSGTLEGIRKNKYTTSSGQLHFGPYLVASSDISNEKNIFHLKRGIKTFKNKEEWPRSKVKEFREYLTLGKSASQQFIDEARFKGRKLYGFKETSKTYNINVWQDGFTPYFDMIELMDLIPEYFLAETRQVK
>NC_019954.2|WP_015294800.1|135865_136525_+|hypothetical-protein
MSEYKITIKLESNCMLGAGEGWGSVIDADIVFDNVGLPYLPARRLKGCLRESAKEVLEMMECAGIKKFESQIIDKVFGCSGDATGAGIVFNNLYLPNYKDVYDWCKWALQECNSAVSPEIIVNSFTSIKQQTSINNEGIADDKSLRTFRVLKRGIEFEGAVNIKEEDKEAVDLLALACLNLRYIGTMRNRGYGKIVCRFKKGNEDLSQSCIEQIEREAI

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Crispr_ID: NC_019954_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019954_2

131275-132509

TypeIII

Consensus_repeat	Method
GTTTATAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTATAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder
GTTTATAGCCTACCTATAAGGAATTGAAAC	CRT

18 spacers

cas2,cas3,cas5,cas7b,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

The CRISPR arrays of NC_019954_2

>merge|NC_019954|2|131275-132509|PILER-CR,CRISPRCasFinder,CRT
GTTTATAGCCTACCTATAAGGAATTGAAACTATTTTCTTTTTTTTATGCATCATAGACACTTCAAGTATTTATAGCCTACCTATAAGGAATTGAAACGGGAAAATACAGGTAAGGAATTGTTTATAAATGCGAAGTTTATAGCCTACCTATAAGGAATTGAAACTCACCAGGAACAAAATCAATTTCAGCAATCGATGAAGTTTATAGCCTACCTATAAGGAATTGAAACAACGATATAAAAGTCAAAGATACTGATGTCATAGTGGGTTTATAGCCTACCTATAAGGAATTGAAACTCTCTTTCAGCAAATCTACGGGCTATCCTCTTGGCGTAGTTTATAGCCTACCTATAAGGAATTGAAACGTGCTGAGCCGCTAAATGTGATTGTGCTGTTTACTTTGTTTATAGCCTACCTATAAGGAATTGAAACTCTGTTCCGTATCCTTTTTGCCATAAACCAGTTTTGTGTTTATAGCCTACCTATAAGGAATTGAAACATTGCTTCTTCAACACCTTTTTCAATTCCAGTGTGGTTTATAGCCTACCTATAAGGAATTGAAACGTAGATAGAAACCCATACTTAGATAGAAGCCTTCTTAACGTTTATAGCCTACCTATAAGGAATTGAAACACCAATGCAGTTAAATAAACTTTTTAATGATCTACTAAGTTTATAGCCTACCTATAAGGAATTGAAACGTAATTATGGGGCCTTTTATTATCCTAACGTCAAGAGGTTTATAGCCTACCTATAAGGAATTGAAACCATTTTATGCAGAAGAGGATGGATTAGACTTTGAAGAGTTTATAGCCTACCTATAAGGAATTGAAACTCTTCTCTCCGTTGTCTTTGTTTCGCTGTCTCCCTCTCGTTTATAGCCTACCTATAAGGAATTGAAACGTCCAATCGGTCTTTACCTCCACCATTTGAAACCTCGTTTATAGCCTACCTATAAGGAATTGAAACTCATCATGGTTATCCAGCTTATTAACGAGCTGGGCCGTTTATAGCCTACCTATAAGGAATTGAAACTATCATCAGCCGCCGCTCCTTCCGCCGGTATGAATTGTTTATAGCCTACCTATAAGGAATTGAAACTTTGGTATGATTTTCAGGGTGTTGGTGGTAGAACAGGTTTATAGCCTACCTATAAGGGATTGAAACAAATATTCTTTTTTAAGGCATCGCATATCCTCAAGCAAGTTGTTAACATACCTATAAAGGCTTGAAAT

>NC_019954|2|1|131275-132441|PILER-CR
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATTTTCTTTTTTTTATGCATCATAGACACTTCAAGT
ATTTATAGCCTACCTATAAGGAATTGAAAC	GGGAAAATACAGGTAAGGAATTGTTTATAAATGCGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCACCAGGAACAAAATCAATTTCAGCAATCGATGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AACGATATAAAAGTCAAAGATACTGATGTCATAGTGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTCTTTCAGCAAATCTACGGGCTATCCTCTTGGCGTA
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTGCTGAGCCGCTAAATGTGATTGTGCTGTTTACTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTGTTCCGTATCCTTTTTGCCATAAACCAGTTTTGT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATTGCTTCTTCAACACCTTTTTCAATTCCAGTGTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTAGATAGAAACCCATACTTAGATAGAAGCCTTCTTAAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACCAATGCAGTTAAATAAACTTTTTAATGATCTACTAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTAATTATGGGGCCTTTTATTATCCTAACGTCAAGAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATTTTATGCAGAAGAGGATGGATTAGACTTTGAAGA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTTCTCTCCGTTGTCTTTGTTTCGCTGTCTCCCTCTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTCCAATCGGTCTTTACCTCCACCATTTGAAACCTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCATCATGGTTATCCAGCTTATTAACGAGCTGGGCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATCATCAGCCGCCGCTCCTTCCGCCGGTATGAATT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTGGTATGATTTTCAGGGTGTTGGTGGTAGAACAG
GTTTATAGCCTACCTATAAGGGATTGAAAC

>NC_019954|2|2|131275-132509|CRISPRCasFinder
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATTTTCTTTTTTTTATGCATCATAGACACTTCAAGT
ATTTATAGCCTACCTATAAGGAATTGAAAC	GGGAAAATACAGGTAAGGAATTGTTTATAAATGCGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCACCAGGAACAAAATCAATTTCAGCAATCGATGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AACGATATAAAAGTCAAAGATACTGATGTCATAGTGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTCTTTCAGCAAATCTACGGGCTATCCTCTTGGCGTA
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTGCTGAGCCGCTAAATGTGATTGTGCTGTTTACTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTGTTCCGTATCCTTTTTGCCATAAACCAGTTTTGT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATTGCTTCTTCAACACCTTTTTCAATTCCAGTGTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTAGATAGAAACCCATACTTAGATAGAAGCCTTCTTAAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACCAATGCAGTTAAATAAACTTTTTAATGATCTACTAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTAATTATGGGGCCTTTTATTATCCTAACGTCAAGAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATTTTATGCAGAAGAGGATGGATTAGACTTTGAAGA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTTCTCTCCGTTGTCTTTGTTTCGCTGTCTCCCTCTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTCCAATCGGTCTTTACCTCCACCATTTGAAACCTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCATCATGGTTATCCAGCTTATTAACGAGCTGGGCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATCATCAGCCGCCGCTCCTTCCGCCGGTATGAATT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTGGTATGATTTTCAGGGTGTTGGTGGTAGAACAG
GTTTATAGCCTACCTATAAGGGATTGAAAC	AAATATTCTTTTTTAAGGCATCGCATATCCTCAAGCAA
GTTGTTAACATACCTATAAAGGCTTGAAAT

>NC_019954|2|1|131275-132509|CRT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATTTTCTTTTTTTTATGCATCATAGACACTTCAAGT
ATTTATAGCCTACCTATAAGGAATTGAAAC	GGGAAAATACAGGTAAGGAATTGTTTATAAATGCGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCACCAGGAACAAAATCAATTTCAGCAATCGATGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AACGATATAAAAGTCAAAGATACTGATGTCATAGTGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTCTTTCAGCAAATCTACGGGCTATCCTCTTGGCGTA
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTGCTGAGCCGCTAAATGTGATTGTGCTGTTTACTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTGTTCCGTATCCTTTTTGCCATAAACCAGTTTTGT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATTGCTTCTTCAACACCTTTTTCAATTCCAGTGTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTAGATAGAAACCCATACTTAGATAGAAGCCTTCTTAAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACCAATGCAGTTAAATAAACTTTTTAATGATCTACTAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTAATTATGGGGCCTTTTATTATCCTAACGTCAAGAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATTTTATGCAGAAGAGGATGGATTAGACTTTGAAGA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTTCTCTCCGTTGTCTTTGTTTCGCTGTCTCCCTCTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTCCAATCGGTCTTTACCTCCACCATTTGAAACCTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCATCATGGTTATCCAGCTTATTAACGAGCTGGGCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATCATCAGCCGCCGCTCCTTCCGCCGGTATGAATT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTGGTATGATTTTCAGGGTGTTGGTGGTAGAACAG
GTTTATAGCCTACCTATAAGGGATTGAAAC	AAATATTCTTTTTTAAGGCATCGCATATCCTCAAGCAA
GTTGTTAACATACCTATAAAGGCTTGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019954.2\|WP_023211308.1\|130000_130957_+\|ATP-grasp-domain-containing-protein	unknown	unknown	gnl\|CDD\|234948
NC_019954.2\|WP_013777243.1\|116907_117960_+\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_019954.2\|WP_013777245.1\|118780_121270_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_019954.2\|WP_013777259.1\|140023_141640_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
NC_019954.2\|WP_013777248.1\|122922_124317_+\|glutamate-mutase-L	unknown	unknown	gnl\|CDD\|379405
NC_019954.2\|WP_013777256.1\|134295_135864_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	unknown
NC_019954.2\|WP_013777252.1\|128442_128754_+\|DUF4387-domain-containing-protein	unknown	unknown	gnl\|CDD\|379559
NC_019954.2\|WP_013777260.1\|141877_142273_+\|hypothetical-protein	csx20	xls002255_csx20_CAS-I:CAS-III	unknown
NC_019954.2\|WP_013777246.1\|121829_122093_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_019954.2\|WP_013777258.1\|139463_140021_+\|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl\|CDD\|274900
NC_019954.2\|WP_013777262.1\|143808_144111_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_019954.2\|WP_013777255.1\|132919_134299_+\|hypothetical-protein	csx1	mkCas0112_csx1_CAS-III	unknown
NC_019954.2\|WP_013777257.1\|138081_139467_+\|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187857
NC_019954.2\|WP_013777261.1\|143220_143619_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_015294800.1\|135865_136525_+\|hypothetical-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
NC_019954.2\|WP_013777247.1\|122469_122892_+\|methylaspartate-mutase-subunit-S	unknown	unknown	gnl\|CDD\|179400
NC_019954.2\|WP_013777244.1\|117962_118727_+\|CRISPR-associated-protein-Cas5	cas5	cd09692_cas5_CAS-I-B	gnl\|CDD\|187823
NC_019954.2\|WP_013777251.1\|127070_128441_+\|acyclic-terpene-utilization-AtuA-family-protein	unknown	unknown	gnl\|CDD\|377804
NC_019954.2\|WP_013777249.1\|124336_125791_+\|methylaspartate-mutase-subunit-E	unknown	unknown	gnl\|CDD\|377651
NC_019954.2\|WP_023211309.1\|136525_138082_+\|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	gnl\|CDD\|131722

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_019954.2\|WP_013777255.1\|132919_134299_+\|hypothetical-protein	csx1	mkCas0112_csx1_CAS-III	1.7e-116	384.3	13.4
NC_019954.2\|WP_013777243.1\|116907_117960_+\|type-I-CRISPR-associated-protein-Cas7	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	2.1e-59	195.9	0.9
NC_019954.2\|WP_013777245.1\|118780_121270_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	3.8e-62	205.3	10.3
NC_019954.2\|WP_013777259.1\|140023_141640_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	6.2e-126	416.6	6.1
NC_019954.2\|WP_013777256.1\|134295_135864_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	2.7e-99	327.7	0.0
NC_019954.2\|WP_013777260.1\|141877_142273_+\|hypothetical-protein	csx20	xls002255_csx20_CAS-I:CAS-III	2.4e-50	164.6	0.2
NC_019954.2\|WP_013777258.1\|139463_140021_+\|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	2e-38	126.7	0.1
NC_019954.2\|WP_013777257.1\|138081_139467_+\|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	1.5e-35	117.3	0.9
NC_019954.2\|WP_015294800.1\|135865_136525_+\|hypothetical-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	3.6e-50	165.1	0.0
NC_019954.2\|WP_013777244.1\|117962_118727_+\|CRISPR-associated-protein-Cas5	cas5	cd09692_cas5_CAS-I-B	1.5e-23	78.1	0.0
NC_019954.2\|WP_013777246.1\|121829_122093_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	2.8e-30	99.1	1.5
NC_019954.2\|WP_023211309.1\|136525_138082_+\|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	1e-23	78.9	0.0

Protein	Function_ID	Function_description	E-value
NC_019954.2\|WP_023211308.1\|130000_130957_+\|ATP-grasp-domain-containing-protein	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	3.87702e-54
NC_019954.2\|WP_013777243.1\|116907_117960_+\|type-I-CRISPR-associated-protein-Cas7	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.25218e-49
NC_019954.2\|WP_013777245.1\|118780_121270_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.31671e-47
NC_019954.2\|WP_013777259.1\|140023_141640_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	1.25276e-76
NC_019954.2\|WP_013777248.1\|122922_124317_+\|glutamate-mutase-L	gnl\|CDD\|379405	pfam13941, MutL, MutL protein. This small family includes, GlmL/MutL from Clostridium tetanomorphum and Clostridium cochlearium. GlmL is located between the genes for the two subunits, epsilon (GlmE) and sigma (GlmS), of the coenzyme-B12-dependent glutamate mutase (methylaspartate mutase), the first enzyme in a pathway of glutamate fermentation. Members shows significant sequence similarity to the hydantoinase branch of the hydantoinase/oxoprolinase family.	0
NC_019954.2\|WP_013777252.1\|128442_128754_+\|DUF4387-domain-containing-protein	gnl\|CDD\|379559	pfam14330, DUF4387, Domain of unknown function (DUF4387). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are approximately 110 amino acids in length. There is a conserved RSKN sequence motif.	2.00683e-57
NC_019954.2\|WP_013777246.1\|121829_122093_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.91101e-32
NC_019954.2\|WP_013777258.1\|139463_140021_+\|TIGR03984-family-CRISPR-associated-protein	gnl\|CDD\|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	9.60297e-35
NC_019954.2\|WP_013777257.1\|138081_139467_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	1.85324e-18
NC_019954.2\|WP_013777262.1\|143808_144111_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.25219e-15
NC_019954.2\|WP_015294800.1\|135865_136525_+\|hypothetical-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.92224e-11
NC_019954.2\|WP_013777247.1\|122469_122892_+\|methylaspartate-mutase-subunit-S	gnl\|CDD\|179400	PRK02261, PRK02261, methylaspartate mutase subunit S; Provisional.	3.48999e-86
NC_019954.2\|WP_013777244.1\|117962_118727_+\|CRISPR-associated-protein-Cas5	gnl\|CDD\|187823	cd09692, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.53955e-18
NC_019954.2\|WP_013777251.1\|127070_128441_+\|acyclic-terpene-utilization-AtuA-family-protein	gnl\|CDD\|377804	pfam07287, AtuA, Acyclic terpene utilisation family protein AtuA. This family consists of several bacterial and plant proteins of around 400 residues in length. One member of this family has been characterized in Pseudomonas citronellolis as AtuA, a member of a gene cluster that is essential for the acyclic terpene utilisation (Atu) pathway.	1.34325e-17
NC_019954.2\|WP_013777249.1\|124336_125791_+\|methylaspartate-mutase-subunit-E	gnl\|CDD\|377651	pfam06368, Met_asp_mut_E, Methylaspartate mutase E chain (MutE). This family consists of several methylaspartate mutase E chain proteins (EC:5.4.99.1). Glutamate mutase catalyzes the first step in the fermentation of glutamate by Clostridium tetanomorphum. This is an unusual isomerisation in which L-glutamate is converted to threo-beta-methyl L-aspartate.	0
NC_019954.2\|WP_023211309.1\|136525_138082_+\|hypothetical-protein	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	8.18086e-18

>NC_019954.2|WP_023211308.1|130000_130957_+|ATP-grasp-domain-containing-protein
MKIAILIDEPRVSYLPGEEGLNEDLQKRKTVKNLKEVLSKRFECSLVKADSDIISKLQNENVSLVFNLCNGIRGETRQAQIPAILEFSGIPYTGSSILGHTLAINKNYACKVFKGSGVTTPEFISIYDKDDLMQLRNKEIKFPVLVKPCDEGSGRGIHQDSLVYDFRSLKRKVQQELRLYNPPIMVTEYIKGREFTVGILGNGNNLKVLPILEISFEALPDDLAKFYSFEVKANYADKTIFRCPAPLDNKLKTKIENTAKKAYNALSLRDYARVDVRVKDDTPYVLEVNSLPGLQKGYSDITKMASACNLAMKALSLK
>NC_019954.2|WP_013777252.1|128442_128754_+|DUF4387-domain-containing-protein
MGIPITEVAEVIRSKNSGPYELTMDIIFKDFDSYENVKQKNIINKKLISSLYQIPEEDIISIINFDPAKAIKITIKRPLVAGAVGESDVYGAQQHAPLLGIEV
>NC_019954.2|WP_013777251.1|127070_128441_+|acyclic-terpene-utilization-AtuA-family-protein
MEELKVLSPTAILGYGFPEESFQRGLEQHPDFIAVDAGSTDPGPYYLGAGVSFTDRQAVKRDLKLMLKAGKKLKIPVLVGTAGGSGANEHLYWTEDIIKEIAREENLELKVAVIEAQIPKEEILKKYEEGKIEPLAPAGELSREDIEETTRIVAQMGVEPIIDALENDVDLVLAGRAFDPTAFAAPCIKAGFPKGLALHMGKILECASIAATPGSGSDCMMGTLRHDCFILEALNPKRKCTVTSIAAHTLYEKDDPYRLHGPGGIINLEETEFTQIDERRVKVSGSKFIPSEEYTIKLEGAKKTGYRTISIAGTRDPIMINQIDDILEAVKDMAKNNFSNIKSDDYQILFALYGKDGVMGKLEPLKDKPSHEIGIIIEVVAKTQEMANTICSFTRSSLLHYGYPGRIATAGNLALRYSPSDIEAGEVYEFSIYHLLAVEDPKEYFPITVKTIKGSE
>NC_019954.2|WP_013777249.1|124336_125791_+|methylaspartate-mutase-subunit-E
MEVQNKKWDMKKFSEMRQEVLNQWPTGKEVDFEEAVRYHQNLPKNQIMTNKLREAATKNNTLIQPRAGVALLDEHIELLKFLRQKGKADVLPTTIDSYTRQNRYEEAEKGIKESEKAGRSLLNGFPAVNYGVKKCRKVIESVDCPVQVRHGTPDARLLAEITLAGGFTDFEGGGISYNVPYAKKISIEQSIYYWQYVDRLVGIYEENGISLNREPFGPLTGTLVPPCISHSIGIIEGLLAAEQGVRNITLGYGQCGNLIQDVAAVETLKELSAEYLKDYDVMLTTAFHQWMGGFPQDEAQAFGVISWGAATAALSKATKVIVKTPHEAFGVPTKEANAEGLRATRQVINMLKDQRMISSQELEKEKEIIKRETRQILSKVYELGEGDWAKGAVRAFEAGVLDVPFAPSQFNAGKILPARDNSGAVRFLNFGSIPFDDKIKEFHRRKLAERAKAENREVSFQMVIDDIYAIGQGMLVGRMDSKIA
>NC_019954.2|WP_013777248.1|122922_124317_+|glutamate-mutase-L
MELALLIDIGSTYTKVTAVDLETVELKARAQAATTVAEDVNIGINKALEELKAMGIDPAKAKHKLACSSAAGGLKMVAVGLVPELTTEAAKRAALGAGAKVGHVFCYELTDDELNQIARYSPDIILLAGGTDGGNKDVIIHNAEKLAELKVDAPIIVAGNKTAASAAEKALRAASKEVYVTENVMPKLECLNIEPAKKIIREVFLSKIIYAKGLSKVSNYVDSPIIPTPSAVMKAAELLAKGSDNEAGYGEVMIVDIGGATTDVDSAATGEPTKAGVTLRGLEEPFIKRTVEGDLGMRYSALALVEEVGIKNMLKNYLPCGMDEKTLQEYVKKISIDTDYVPCNETDKQIDCGIAKAATDLAVKRHVGRIETVYSPFGAAYVQHGKDLTKLDFMIATGGVLIYSENPKEILRHGLYDSSRPEVLAPENPKMLLDEKYLLSSLGLLSEIAPDKALNLAKKYLKEL
>NC_019954.2|WP_013777247.1|122469_122892_+|methylaspartate-mutase-subunit-S
MKYDDKKTIVLGVIGSDVHSVGIRILDEAFSEAGFNVVNIGVLSSQEDFINAAIETDADAILVSSLYGHGELDCKGFKEKCVEAGLGDVILYVGGNLVVGKQDWPATEKKFLDMGFDRVYPPGTLPEIPINDLKNDLGIK
>NC_019954.2|WP_013777246.1|121829_122093_+|CRISPR-associated-endonuclease-Cas2
MFIILVYDVGEKRVAKVLKICRKYLTWVQNSVLEGEISAANFKKLKLELKRVIDEDEDSVIFYILRTTKYSERQSMGIKKGGDELFI
>NC_019954.2|WP_013777245.1|118780_121270_+|CRISPR-associated-helicase/endonuclease-Cas3
MQYLAHYDKGKQEKQFLNEHLTSVATLAKTRVLPCVVFDDLDSSKIEEICYWTGYFHDLGKYSIYFQDYLQKGISSPLKNHAHISACFAYSYLSNKATSRFDSDKTLLFFIYTCIRLHHTSLKCKGLFNYGIWEDLIPISKNISDKSNEIIKDLGLAQDMSDEEFRALIDIEKFKANAFSLERIPLMFNNSRISNPKWYFLLIYLFSMLIDTDKLDSANIKSEKISTVPPENVTSYIFSKHGKKSDTELINNREKARKSMIEVVESLSNDALKNVRFFTITAPTGIGKTLSSLQCALDLQQKIAETEGYTPRIITAIPFINIIEQNKLEYENVMGKECKIAVHHRLSDFGVAKSKDETIPVDRVLLETESWEADVILTTFVQLFQSLFSSTNKMLKKINKLAGSIVILDEIQAIPEKYMPLIGASLQMIAKYYGTRFILMTATQPKILQFGSMLLQYTEKNSKQIESIELLPNHEEYFKCLTRTKFVPLLENVLDTEDFLDVFFNKWDYTKSCLIVVNTIKRSIDVYKKIKEELALRGFKLPVYYLSTNIIPLKRRDVIQEVKDLLESEQPVILVSTQTIEAGVDLDFDMAFRDFAPLDSLVQTAGRVNRQGKKGNYSPVYIIQLENDSHYIYDLSLREVTINLLKELLTAQEEIKETDYVSLTKRYYDLILKEGVDDASKRIWNDGILKLDFDKLEEFKLIESPGEVYDVFIEKELSATNLADAYEQVLGYKDSFDYDLSKIFPDFKSDQFEKTLNVFQRKALLRLIMAKMHDYIIQVRVSRLKENRPVEFKERGNIESSLYWVPPTKCDDYYDEDTGFKDESGDGFI
>NC_019954.2|WP_013777244.1|117962_118727_+|CRISPR-associated-protein-Cas5
MKVISFHLKGKMAHFRKFYSNASALSYFVPPRTTICGIIAGLLGLERDGYYDDFSLDNCKITITSCSPLKKTMQKLNYLMIKSVQDLNGSQENHSQTATELVIPQDIRSGYIDYKIWFHHCDNKIMSDVESIINDCSPFYESKWSCVALGSAFNLGWIEKGEILEAEEKFVKSKKLVSSSIPIHNIEEIKVDEINTNKVYKLIKEEVPLEFDQQRRITKEGLKEILINVNGDYIPAVVDSFVSLDNGEVITWLE
>NC_019954.2|WP_013777243.1|116907_117960_+|type-I-CRISPR-associated-protein-Cas7
MLINQNSDFLFGFQATMSNPNGDPDQENKPRMDYETSTALVSDARRKRDVRDFLKNKGYKIFVDTLADQKVPMDKMLEYITDTFLENSGNIELLFKENPNLKVQWEKVFGTTENPNKEYNEKKEKLKKNKDFIRLNNIFLTEIIKKELIDIRLFGSAMAVEGVSKTFTGPVQLNWGYSLHPVELIKSNTITSIMNEDNSTFGKKYKLYYALMAHYGTINKYNAKLTGMTEKDRELFRKALGQSLMANQTDSKQGQEPIFYLEILYAPEFDGYLGDLRRFLNVEYATYAIRSLDDIKVDFSRLNDAINNVKNKGYIDKVIGWVNPFIPNESFMNLPEFENIDLLAPIKTEE
>NC_019954.2|WP_013777255.1|132919_134299_+|hypothetical-protein
MDIFTSFTDLVLLVGTNPLPNYIVIKYFLKHNEKLKRIWLIYSEETNVQAGTEELAENITSVIKKEFLSNKPDLKFKHMPLSDVGSASTILDELQRNMKIEVSSPNIFHLNYTGGTKSMAVQTYKYFLENFGKRCTFSYLDGRDFKLKGDQSSAHVTKDLRYEIGISVESLFELHGYEKKGGQNNPSYPDTVKKFEEIIRLGKLNEYLSWKKSTIREFFYEGSNCIKKKNRFLTHNNIYSDEDVKRFKQNFKDKMTDEIILELLKSIPKENSILDENGDIWVPDKSTTNKEYKERVGDSVENFLDGKWLEVYVYNVICQKIKQNEKLNELYKKGQLIIDNNYEIKKKNTEKKHFEIDVILLNGYQVCGISCTTASDDSTCKNKGFEIIHRARQMGGEEAKSILIACLEDKESRSIEDFYEDLKDTSGSRTHEFMVLGLKDLTPEKLWEKIYEHIWGADL
>NC_019954.2|WP_013777256.1|134295_135864_+|hypothetical-protein
MSKVTAILADTVSIQKYVYSSNRLKENIGASSIIANIYKESLANTLEKTLEHGVSLDEWEKQPETIAIKNSNTDFEVGYIGGGNALLFFNNEATAKEFISEWTRSLLLEAPSLNVAFAISEFNIDNFQNEMKNLFKQLEINKSKYFPQTFLPKHGITADCPYSGLSAEVYKPGTNDEKGAYISSASYVKYKHIDIDDAKVEVERISNGKFSLTTNIEKLGQTKGQNHIAIVHIDGNSMAEHFKSCENLVAIRKLSKRLKDIMQSVYEEFLNYIFEQMDLLLSDESGFNIQLENGKYIIPFRPILREGDDITFITDGRLGIPFAQKYLELMSDKTLYNENKLSACAGVAIIKTKYPFFRGYNLTEELCQSAKREARENKGTSWLDFHISYGGFSGTLEGIRKNKYTTSSGQLHFGPYLVASSDISNEKNIFHLKRGIKTFKNKEEWPRSKVKEFREYLTLGKSASQQFIDEARFKGRKLYGFKETSKTYNINVWQDGFTPYFDMIELMDLIPEYFLAETRQVK
>NC_019954.2|WP_015294800.1|135865_136525_+|hypothetical-protein
MSEYKITIKLESNCMLGAGEGWGSVIDADIVFDNVGLPYLPARRLKGCLRESAKEVLEMMECAGIKKFESQIIDKVFGCSGDATGAGIVFNNLYLPNYKDVYDWCKWALQECNSAVSPEIIVNSFTSIKQQTSINNEGIADDKSLRTFRVLKRGIEFEGAVNIKEEDKEAVDLLALACLNLRYIGTMRNRGYGKIVCRFKKGNEDLSQSCIEQIEREAI
>NC_019954.2|WP_023211309.1|136525_138082_+|hypothetical-protein
MAYLKITINLLSPIILSADVPDNNLTETFDYIPASSLIGLFAAKYISQEHLEYAHNNTNFYKWFLKGDLVFTNAYISEKDDYDEIDMLPTPLCIKKQKKGERILNILLNTEDEQTVFISPYSYIERSTIKTGELAKKINFHHMRDRLRGHTKDEAMFNYEALMPGQIFKGEIYGDSTTLREFRKTFGEKIIGRLGKSRNTEYGEVEISLSKIINEDIDALTDEDLEDEDYILLTFISPCILVNENGFPDPSLPNLKCYLENIWGKDSFEIENCVMRTTSIENYISVWKMKRPIETAISAGSTVKLVFKNNLPFENIKNGFEKMANDGIGERRNEGFGRIKLNMATAEEYYKKTIKPNQNKPESKVPQGAKQIFENVIQNMFKEEFERKAYEDAAGFSCLPSNSLLGKLGLILSKCQKEEEFKKSIDELRNNAKSQLEDCRNKTKRCNLYEYIKNFDTTKIIESIYNDITKADYLKLTKISEYNVKDEKELLLELWKIYFGVFFRRMRQRQKVAKKEVL
>NC_019954.2|WP_013777257.1|138081_139467_+|hypothetical-protein
MDNAKVTGRFLIRGKLDLESPLLIGTGEKGYIDISVQKDDNGIPYIPASSMRGVLRHYFFNNLTIQGTDKTQIEYFWGSSKNQDDKDTYQSSFILEDLYALNKPNIVVRDGIKIDNKRGIAEDEKKFDYEVVEPGAEFGFNAEVVLRECFSKEMFLKIISTLISALENGQISLGSMTTKGFGRCRLSECKVYEYDFTQGTNKTKDVILWLKGESTEEQLITLDLNEIFLPKKNKFSLKATFNIRNSLIVKAYTGMPKEPDSIHIISAGKDILPGTSLKGALRARAVKIINTLEGQSDELVKELFGWASDEASDKNKKIKSRLILDEAYIQNSVKETQFRTKIDRFTGGVIKTALFDSTPVWSGKDNAKVTINIEINDCKNWEAGLVMLLLKDLWTGDLAAGGEKNIGRGTFEGQSAEIYFNGNHYIIEQRGDKLRVNCGKDELENLVSAFVEKCKSGRAGV
>NC_019954.2|WP_013777258.1|139463_140021_+|TIGR03984-family-CRISPR-associated-protein
MNGLKLANIKSTSKPMELNIASWQDLQKNINENFKEKSYAVVYLDYKVLIGKINEKNLKFYNDEVFDPKFIVKMRVFNEEKELLLWRRDEYKFEGRMRLDNEGDNIQYFVEVDQVLWGNPKSINNEWTVLKEARGTEIYIPYLYKPEYSSSKRLAIRTRNYVGYNEIGQAGYTDCRFVSFCEGGK
>NC_019954.2|WP_013777259.1|140023_141640_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MEKAKLINIRKSKKGKLIGEVQFEDGKTMSIPPGAKLNVSLNNIECSIERNSGAITNITIDEKVIFSKASNSDPVSQKINKKHYTNKTTKQASNKAAQPSKAHAPYNFIPLNDTVIEGQPIPDFDCYHSEHAGLKRFNGYIECQLESITPIYIRDTYTTEEIIKKEESNEDNPDFFSPGGIARIPGSSLRGMIRTMVEIMSWGKFGFYEDKRLFYRGLADKSNLRLEYQNNMSSYDRNTRKSSYKYTIGDHIPENLKRKELIDIPESIFGKISEKQSFASRVFFEDATLMPGQNDIFVSDEPLTPKILSSPKPTTFQHYLEQPSDVTVKNLNHWNTKEAKIRGYKLYWHKDGLGWEYEGNDEEKAKNKRILTKIKPIKPGIKFKYRIRFENLSQEEIGAILFAIDLPENCYHKIGMGKPLGLGTIKIRPALFLINRESRYTNLFENENWNLGVEESNIQKFKDAFEQYVLNQVNKLENSDLSSLWNHERMKHLKVILDFENTKLKGWKQETDYMELKEFKNRPVLSKPLEVYNKFTTN
>NC_019954.2|WP_013777260.1|141877_142273_+|hypothetical-protein
MRQAFLLFSHQLTKSQQDELENKFKVDKIIYLPSDLQSIWSNVPPELPSIKDYLEEIFCWLKEHSKPNDIVLVQGEFGAVFLTANFCIKEGLVPIYSTTRRDVAETILDDETIQTKRNFIHVRFREFEKWD
>NC_019954.2|WP_013777261.1|143220_143619_+|hypothetical-protein
MKKYCIIILIVCMMLVLTACGNPNSEVVGEYDTSKLGGDFVKSSNEAYAIGANKDKMPVFKDTDKAFKQALIDYAEGFKAIQKEFNLKPINKKNWEAYKTYGWQLSADNDEEIRKQGREITQFFDIYENSFK
>NC_019954.2|WP_013777262.1|143808_144111_-|helix-turn-helix-transcriptional-regulator
MNIGHRIKQIRIAKGLQGIQLAEKVGITNVYLSYLENGTKIPSIETLQKICDALGITLSEFFMDENANLPPEYQELIENVKVLSPKQLELLNEFLKTLRQ

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Crispr_ID: NC_019954_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019954_3

142529-143157

TypeIII

Consensus_repeat	Method
GTTTATAGCCTACCTATAAGGGATTGAAAC	PILER-CR
GTTTATAGCCTACCTATAAGGGATTGAAAC	CRISPRCasFinder
GTTTATAGCCTACCTATAAGGGATTGAAAC	CRT

9 spacers

csx20,csm3gr7,csx19,csx10gr5,cas10,csx1

The CRISPR arrays of NC_019954_3

>merge|NC_019954|3|142529-143157|PILER-CR,CRISPRCasFinder,CRT
GTTTATAGCCTACCTATAAGGGATTGAAACTGGACTTAAAGTTCATCCCATCGCTGTCGCAATGTGGTTTATAGCCTACCTATAAGGGATTGAAACACGACATGAACCAACCAGCAGAGATAACAGATACACAGTTTATAGCCTACCTATAAGGGATTGAAACTTTGTTATTATAAGGCTATTATGTTCTTTACATCTATAGTTTATAGCCTACCTATAAGGGATTGAAACCGGAAGCAAGAGAACCAATTACAATAACATTCAAAGGAGTTTATAGCCTACCTATAAGGGATTGAAACCTTGCAACAGTGTGGGAACCAAAAAGGAACTTTAGTGGTTTATAGCCTACCTATAAGGGATTGAAACTTTTTTTACGTAGGCCGTTGTAATCCCTAATGATAGCGTTTATAGCCTACCTATAAGGGATTGAAACTTCCCAACCGCCCCAGGATCTTTCCCGCCATGCTAAGTTTATAGCCTACCTATAAGGGATTGAAACTTTCTTGTGATGATCTTGATACATTGTAGTTAGGGGTTTATAGCCTACCTATAAGGGATTGAAACCGTCTCCAAATTCGTTGTATTCTAGACCTATACTGGTTTATAGCCTACCTATAAGGGATTGAACT

>NC_019954|3|2|142529-143157|PILER-CR
GTTTATAGCCTACCTATAAGGGATTGAAAC	TGGACTTAAAGTTCATCCCATCGCTGTCGCAATGTG
GTTTATAGCCTACCTATAAGGGATTGAAAC	ACGACATGAACCAACCAGCAGAGATAACAGATACACA
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTTGTTATTATAAGGCTATTATGTTCTTTACATCTATA
GTTTATAGCCTACCTATAAGGGATTGAAAC	CGGAAGCAAGAGAACCAATTACAATAACATTCAAAGGA
GTTTATAGCCTACCTATAAGGGATTGAAAC	CTTGCAACAGTGTGGGAACCAAAAAGGAACTTTAGTG
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTTTTTTACGTAGGCCGTTGTAATCCCTAATGATAGC
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTCCCAACCGCCCCAGGATCTTTCCCGCCATGCTAA
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTTCTTGTGATGATCTTGATACATTGTAGTTAGGG
GTTTATAGCCTACCTATAAGGGATTGAAAC	CGTCTCCAAATTCGTTGTATTCTAGACCTATACTG
GTTTATAGCCTACCTATAAGGGATTGAACT

>NC_019954|3|3|142529-143157|CRISPRCasFinder
GTTTATAGCCTACCTATAAGGGATTGAAAC	TGGACTTAAAGTTCATCCCATCGCTGTCGCAATGTG
GTTTATAGCCTACCTATAAGGGATTGAAAC	ACGACATGAACCAACCAGCAGAGATAACAGATACACA
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTTGTTATTATAAGGCTATTATGTTCTTTACATCTATA
GTTTATAGCCTACCTATAAGGGATTGAAAC	CGGAAGCAAGAGAACCAATTACAATAACATTCAAAGGA
GTTTATAGCCTACCTATAAGGGATTGAAAC	CTTGCAACAGTGTGGGAACCAAAAAGGAACTTTAGTG
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTTTTTTACGTAGGCCGTTGTAATCCCTAATGATAGC
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTCCCAACCGCCCCAGGATCTTTCCCGCCATGCTAA
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTTCTTGTGATGATCTTGATACATTGTAGTTAGGG
GTTTATAGCCTACCTATAAGGGATTGAAAC	CGTCTCCAAATTCGTTGTATTCTAGACCTATACTG
GTTTATAGCCTACCTATAAGGGATTGAACT

>NC_019954|3|2|142529-143157|CRT
GTTTATAGCCTACCTATAAGGGATTGAAAC	TGGACTTAAAGTTCATCCCATCGCTGTCGCAATGTG
GTTTATAGCCTACCTATAAGGGATTGAAAC	ACGACATGAACCAACCAGCAGAGATAACAGATACACA
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTTGTTATTATAAGGCTATTATGTTCTTTACATCTATA
GTTTATAGCCTACCTATAAGGGATTGAAAC	CGGAAGCAAGAGAACCAATTACAATAACATTCAAAGGA
GTTTATAGCCTACCTATAAGGGATTGAAAC	CTTGCAACAGTGTGGGAACCAAAAAGGAACTTTAGTG
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTTTTTTACGTAGGCCGTTGTAATCCCTAATGATAGC
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTCCCAACCGCCCCAGGATCTTTCCCGCCATGCTAA
GTTTATAGCCTACCTATAAGGGATTGAAAC	TTTCTTGTGATGATCTTGATACATTGTAGTTAGGG
GTTTATAGCCTACCTATAAGGGATTGAAAC	CGTCTCCAAATTCGTTGTATTCTAGACCTATACTG
GTTTATAGCCTACCTATAAGGGATTGAACT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019954.2\|WP_013777255.1\|132919_134299_+\|hypothetical-protein	csx1	mkCas0112_csx1_CAS-III	unknown
NC_019954.2\|WP_023211308.1\|130000_130957_+\|ATP-grasp-domain-containing-protein	unknown	unknown	gnl\|CDD\|234948
NC_019954.2\|WP_013777260.1\|141877_142273_+\|hypothetical-protein	csx20	xls002255_csx20_CAS-I:CAS-III	unknown
NC_019954.2\|WP_013777259.1\|140023_141640_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
NC_019954.2\|WP_013777256.1\|134295_135864_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	unknown
NC_019954.2\|WP_013777267.1\|151588_152620_+\|DctP-family-TRAP-transporter-solute-binding-subunit	unknown	unknown	gnl\|CDD\|270393
NC_019954.2\|WP_013777252.1\|128442_128754_+\|DUF4387-domain-containing-protein	unknown	unknown	gnl\|CDD\|379559
NC_019954.2\|WP_013777271.1\|155698_156079_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013777261.1\|143220_143619_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013777258.1\|139463_140021_+\|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl\|CDD\|274900
NC_019954.2\|WP_013777268.1\|152670_153147_+\|TRAP-transporter-small-permease	unknown	unknown	gnl\|CDD\|225632
NC_019954.2\|WP_013777257.1\|138081_139467_+\|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187857
NC_019954.2\|WP_013777270.1\|154445_155696_+\|DUF2088-domain-containing-protein	unknown	unknown	gnl\|CDD\|226392
NC_019954.2\|WP_013777265.1\|148885_150361_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143435
NC_019954.2\|WP_015294800.1\|135865_136525_+\|hypothetical-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
NC_019954.2\|WP_013777266.1\|150667_151240_+\|manganese-catalase-family-protein	unknown	unknown	gnl\|CDD\|153117
NC_019954.2\|WP_013777263.1\|144379_145669_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NC_019954.2\|WP_013777269.1\|153149_154430_+\|TRAP-transporter-large-permease	unknown	unknown	gnl\|CDD\|224509
NC_019954.2\|WP_013777262.1\|143808_144111_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_019954.2\|WP_023211309.1\|136525_138082_+\|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	gnl\|CDD\|131722

Protein	Function_ID	Function_description	E-value
NC_019954.2\|WP_023211308.1\|130000_130957_+\|ATP-grasp-domain-containing-protein	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	3.87702e-54
NC_019954.2\|WP_013777266.1\|150667_151240_+\|manganese-catalase-family-protein	gnl\|CDD\|153117	cd07908, Mn_catalase_like, Manganese catalase-like protein, ferritin-like diiron-binding domain. This uncharacterized bacterial protein family has a ferritin-like domain similar to that of the manganese catalase protein of Lactobacillus plantarum and the bll3758 protein of Bradyrhizobium japonicum. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	7.42448e-62
NC_019954.2\|WP_013777259.1\|140023_141640_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	1.25276e-76
NC_019954.2\|WP_013777252.1\|128442_128754_+\|DUF4387-domain-containing-protein	gnl\|CDD\|379559	pfam14330, DUF4387, Domain of unknown function (DUF4387). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are approximately 110 amino acids in length. There is a conserved RSKN sequence motif.	2.00683e-57
NC_019954.2\|WP_013777267.1\|151588_152620_+\|DctP-family-TRAP-transporter-solute-binding-subunit	gnl\|CDD\|270393	cd13675, PBP2_TRAP_SBP_like_5, Uncharacterized substrate-binding protein of the Tripartite ATP-independent Periplasmic transporter family; the type 2 periplasmic-binding protein fold. This subfamily includes uncharacterized periplasmic substrate-binding proteins similar to TRAP transport systems such as SiaP (a sialic acid binding virulence factor) and TeaA (an ectoine binding protein). TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller membrane of unknown function. The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	9.26939e-165
NC_019954.2\|WP_013777263.1\|144379_145669_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	2.77882e-110
NC_019954.2\|WP_013777268.1\|152670_153147_+\|TRAP-transporter-small-permease	gnl\|CDD\|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	8.05253e-38
NC_019954.2\|WP_013777257.1\|138081_139467_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	1.85324e-18
NC_019954.2\|WP_013777270.1\|154445_155696_+\|DUF2088-domain-containing-protein	gnl\|CDD\|226392	COG3875, COG3875, Uncharacterized conserved protein [Function unknown].	0.00113515
NC_019954.2\|WP_013777265.1\|148885_150361_+\|aldehyde-dehydrogenase	gnl\|CDD\|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
NC_019954.2\|WP_015294800.1\|135865_136525_+\|hypothetical-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.92224e-11
NC_019954.2\|WP_013777258.1\|139463_140021_+\|TIGR03984-family-CRISPR-associated-protein	gnl\|CDD\|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	9.60297e-35
NC_019954.2\|WP_013777269.1\|153149_154430_+\|TRAP-transporter-large-permease	gnl\|CDD\|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	5.06046e-135
NC_019954.2\|WP_013777262.1\|143808_144111_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.25219e-15
NC_019954.2\|WP_023211309.1\|136525_138082_+\|hypothetical-protein	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	8.18086e-18

>NC_019954.2|WP_013777260.1|141877_142273_+|hypothetical-protein
MRQAFLLFSHQLTKSQQDELENKFKVDKIIYLPSDLQSIWSNVPPELPSIKDYLEEIFCWLKEHSKPNDIVLVQGEFGAVFLTANFCIKEGLVPIYSTTRRDVAETILDDETIQTKRNFIHVRFREFEKWD
>NC_019954.2|WP_013777259.1|140023_141640_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MEKAKLINIRKSKKGKLIGEVQFEDGKTMSIPPGAKLNVSLNNIECSIERNSGAITNITIDEKVIFSKASNSDPVSQKINKKHYTNKTTKQASNKAAQPSKAHAPYNFIPLNDTVIEGQPIPDFDCYHSEHAGLKRFNGYIECQLESITPIYIRDTYTTEEIIKKEESNEDNPDFFSPGGIARIPGSSLRGMIRTMVEIMSWGKFGFYEDKRLFYRGLADKSNLRLEYQNNMSSYDRNTRKSSYKYTIGDHIPENLKRKELIDIPESIFGKISEKQSFASRVFFEDATLMPGQNDIFVSDEPLTPKILSSPKPTTFQHYLEQPSDVTVKNLNHWNTKEAKIRGYKLYWHKDGLGWEYEGNDEEKAKNKRILTKIKPIKPGIKFKYRIRFENLSQEEIGAILFAIDLPENCYHKIGMGKPLGLGTIKIRPALFLINRESRYTNLFENENWNLGVEESNIQKFKDAFEQYVLNQVNKLENSDLSSLWNHERMKHLKVILDFENTKLKGWKQETDYMELKEFKNRPVLSKPLEVYNKFTTN
>NC_019954.2|WP_013777258.1|139463_140021_+|TIGR03984-family-CRISPR-associated-protein
MNGLKLANIKSTSKPMELNIASWQDLQKNINENFKEKSYAVVYLDYKVLIGKINEKNLKFYNDEVFDPKFIVKMRVFNEEKELLLWRRDEYKFEGRMRLDNEGDNIQYFVEVDQVLWGNPKSINNEWTVLKEARGTEIYIPYLYKPEYSSSKRLAIRTRNYVGYNEIGQAGYTDCRFVSFCEGGK
>NC_019954.2|WP_013777257.1|138081_139467_+|hypothetical-protein
MDNAKVTGRFLIRGKLDLESPLLIGTGEKGYIDISVQKDDNGIPYIPASSMRGVLRHYFFNNLTIQGTDKTQIEYFWGSSKNQDDKDTYQSSFILEDLYALNKPNIVVRDGIKIDNKRGIAEDEKKFDYEVVEPGAEFGFNAEVVLRECFSKEMFLKIISTLISALENGQISLGSMTTKGFGRCRLSECKVYEYDFTQGTNKTKDVILWLKGESTEEQLITLDLNEIFLPKKNKFSLKATFNIRNSLIVKAYTGMPKEPDSIHIISAGKDILPGTSLKGALRARAVKIINTLEGQSDELVKELFGWASDEASDKNKKIKSRLILDEAYIQNSVKETQFRTKIDRFTGGVIKTALFDSTPVWSGKDNAKVTINIEINDCKNWEAGLVMLLLKDLWTGDLAAGGEKNIGRGTFEGQSAEIYFNGNHYIIEQRGDKLRVNCGKDELENLVSAFVEKCKSGRAGV
>NC_019954.2|WP_023211309.1|136525_138082_+|hypothetical-protein
MAYLKITINLLSPIILSADVPDNNLTETFDYIPASSLIGLFAAKYISQEHLEYAHNNTNFYKWFLKGDLVFTNAYISEKDDYDEIDMLPTPLCIKKQKKGERILNILLNTEDEQTVFISPYSYIERSTIKTGELAKKINFHHMRDRLRGHTKDEAMFNYEALMPGQIFKGEIYGDSTTLREFRKTFGEKIIGRLGKSRNTEYGEVEISLSKIINEDIDALTDEDLEDEDYILLTFISPCILVNENGFPDPSLPNLKCYLENIWGKDSFEIENCVMRTTSIENYISVWKMKRPIETAISAGSTVKLVFKNNLPFENIKNGFEKMANDGIGERRNEGFGRIKLNMATAEEYYKKTIKPNQNKPESKVPQGAKQIFENVIQNMFKEEFERKAYEDAAGFSCLPSNSLLGKLGLILSKCQKEEEFKKSIDELRNNAKSQLEDCRNKTKRCNLYEYIKNFDTTKIIESIYNDITKADYLKLTKISEYNVKDEKELLLELWKIYFGVFFRRMRQRQKVAKKEVL
>NC_019954.2|WP_015294800.1|135865_136525_+|hypothetical-protein
MSEYKITIKLESNCMLGAGEGWGSVIDADIVFDNVGLPYLPARRLKGCLRESAKEVLEMMECAGIKKFESQIIDKVFGCSGDATGAGIVFNNLYLPNYKDVYDWCKWALQECNSAVSPEIIVNSFTSIKQQTSINNEGIADDKSLRTFRVLKRGIEFEGAVNIKEEDKEAVDLLALACLNLRYIGTMRNRGYGKIVCRFKKGNEDLSQSCIEQIEREAI
>NC_019954.2|WP_013777256.1|134295_135864_+|hypothetical-protein
MSKVTAILADTVSIQKYVYSSNRLKENIGASSIIANIYKESLANTLEKTLEHGVSLDEWEKQPETIAIKNSNTDFEVGYIGGGNALLFFNNEATAKEFISEWTRSLLLEAPSLNVAFAISEFNIDNFQNEMKNLFKQLEINKSKYFPQTFLPKHGITADCPYSGLSAEVYKPGTNDEKGAYISSASYVKYKHIDIDDAKVEVERISNGKFSLTTNIEKLGQTKGQNHIAIVHIDGNSMAEHFKSCENLVAIRKLSKRLKDIMQSVYEEFLNYIFEQMDLLLSDESGFNIQLENGKYIIPFRPILREGDDITFITDGRLGIPFAQKYLELMSDKTLYNENKLSACAGVAIIKTKYPFFRGYNLTEELCQSAKREARENKGTSWLDFHISYGGFSGTLEGIRKNKYTTSSGQLHFGPYLVASSDISNEKNIFHLKRGIKTFKNKEEWPRSKVKEFREYLTLGKSASQQFIDEARFKGRKLYGFKETSKTYNINVWQDGFTPYFDMIELMDLIPEYFLAETRQVK
>NC_019954.2|WP_013777255.1|132919_134299_+|hypothetical-protein
MDIFTSFTDLVLLVGTNPLPNYIVIKYFLKHNEKLKRIWLIYSEETNVQAGTEELAENITSVIKKEFLSNKPDLKFKHMPLSDVGSASTILDELQRNMKIEVSSPNIFHLNYTGGTKSMAVQTYKYFLENFGKRCTFSYLDGRDFKLKGDQSSAHVTKDLRYEIGISVESLFELHGYEKKGGQNNPSYPDTVKKFEEIIRLGKLNEYLSWKKSTIREFFYEGSNCIKKKNRFLTHNNIYSDEDVKRFKQNFKDKMTDEIILELLKSIPKENSILDENGDIWVPDKSTTNKEYKERVGDSVENFLDGKWLEVYVYNVICQKIKQNEKLNELYKKGQLIIDNNYEIKKKNTEKKHFEIDVILLNGYQVCGISCTTASDDSTCKNKGFEIIHRARQMGGEEAKSILIACLEDKESRSIEDFYEDLKDTSGSRTHEFMVLGLKDLTPEKLWEKIYEHIWGADL
>NC_019954.2|WP_023211308.1|130000_130957_+|ATP-grasp-domain-containing-protein
MKIAILIDEPRVSYLPGEEGLNEDLQKRKTVKNLKEVLSKRFECSLVKADSDIISKLQNENVSLVFNLCNGIRGETRQAQIPAILEFSGIPYTGSSILGHTLAINKNYACKVFKGSGVTTPEFISIYDKDDLMQLRNKEIKFPVLVKPCDEGSGRGIHQDSLVYDFRSLKRKVQQELRLYNPPIMVTEYIKGREFTVGILGNGNNLKVLPILEISFEALPDDLAKFYSFEVKANYADKTIFRCPAPLDNKLKTKIENTAKKAYNALSLRDYARVDVRVKDDTPYVLEVNSLPGLQKGYSDITKMASACNLAMKALSLK
>NC_019954.2|WP_013777252.1|128442_128754_+|DUF4387-domain-containing-protein
MGIPITEVAEVIRSKNSGPYELTMDIIFKDFDSYENVKQKNIINKKLISSLYQIPEEDIISIINFDPAKAIKITIKRPLVAGAVGESDVYGAQQHAPLLGIEV
>NC_019954.2|WP_013777261.1|143220_143619_+|hypothetical-protein
MKKYCIIILIVCMMLVLTACGNPNSEVVGEYDTSKLGGDFVKSSNEAYAIGANKDKMPVFKDTDKAFKQALIDYAEGFKAIQKEFNLKPINKKNWEAYKTYGWQLSADNDEEIRKQGREITQFFDIYENSFK
>NC_019954.2|WP_013777262.1|143808_144111_-|helix-turn-helix-transcriptional-regulator
MNIGHRIKQIRIAKGLQGIQLAEKVGITNVYLSYLENGTKIPSIETLQKICDALGITLSEFFMDENANLPPEYQELIENVKVLSPKQLELLNEFLKTLRQ
>NC_019954.2|WP_013777263.1|144379_145669_+|serine-dehydratase-subunit-alpha-family-protein
MSNELYQKAIEQVKEEMVPALGVTEPAAIALSAAKAYEVIGGEVKKVTVWVDEGVFKNGFSCAIPGTCEKGNEMAAALGVIAGKPDFGLRVLEDVTEEDVSRAKELIKEGKIEIKVKRGVSDIFIDAIVETDKGKGRAVIKDKHTNIVLVEKDGKEIFKKQLETKTSEGKAFDISRLKLKDLIDIAEHAPYEDISFILEAVRVNDELAQAGKQGEGMELGRGISDLIEEGYLKEDILTYAMAYTGYAVDARMGGVSKPAMSICGSGDHGLVATLPLIAIANKKEIPEEKLVRSILLSYLVTMYIKTFAGRLSAFCGCAVAAGTGSSAGICYLLGGNNEQIGFTIDNMAADITGIICDGGNFGCSLKAVTAASTAILSALLALKNIHIPKDSGIVGNTVEETMQNIGKIASPGMTKTNDVILDIMINRHD
>NC_019954.2|WP_013777265.1|148885_150361_+|aldehyde-dehydrogenase
MNKPIDKNYQLLIGGRWVDAKDGETFETNNPANGELLATCANAGKEDVDEAVKAAWKAFETWKDVSAQEKSGILLKIADLIDENAEKLAMIETLDNGKPIRETRNIDVPLSSDHFRYFAGAIRAEEGQAVMIDKNTLSIILREPIGVVGQIIPWNFPLLMAAWKLAPALAAGCTVVIKPSSSTPLSILELGKLINDVLPPGVVNIVTGSGATTGNYMLEHPGFRKLAFTGSTEVGYSIAEAAAKKLIPSTLELGGKSANIYFPDCPWEKAIEGVQLGILFNQGQVCCAGSRVFVHEDIYEEFLAECVEAFKKIKVGLPWEEDTIMGTQINEGQLKKILNYIEIGKQEGARLACGGSRITENGLDKGCFMQPTIFADVDNKMRIAQEEIFGPVACFLKFKDEEEVIKMANDSEYGLGGAVWTKDINRALKVARGIETGRMWINDYNNLPAHTPFGGYKKSGIGRETHHMMLDHYTQKKNIMISMNENKAGLY
>NC_019954.2|WP_013777266.1|150667_151240_+|manganese-catalase-family-protein
MSEDFVDLKGCKTPETYNKCAYPAPYPEIKVARENPYYGKLLLEDYAGRAGELTAVNQYIYHHFVLEPEYEEVAELLSCVALVEMHHMEILADTILKLGVDPRQRTIATNEVEIYWDAGFVYYGTVLCDMITANIAGEWAAISNYRKHQQMINDLYVKKILERIILDEIYHVQLFSQVTEKYCKPNIKKE
>NC_019954.2|WP_013777267.1|151588_152620_+|DctP-family-TRAP-transporter-solute-binding-subunit
MSKKNLALLLISLLIIGLLAGCGGGQQNGNDAAPSGNQDKGGTITIKVGHVLAPTHPYTLGLQKFAELVDEKTDGKIKVEVFHSSQLGNERDMVEALQLGTQEMTLVSTAPLASFTKQFLVFDLPFVFKDTESARKVLDSELGQGLLNSLESQGIMGLCYFENGFRHVTNSKHPINKPEDLKGIKIRTMENPIHMATFKVMGADPTPMAFGELFTALQQKTIDAQENPLPIIETSKFYEVQEYLSLTGHFYAPAPLLISKSFFEGLAPELQAALKEAAIEARDYERGLLDDMNAKLVEELKEKGMKVNEPDKTLFVEAVQSVYKQFESDITPELIQKVVDAQK
>NC_019954.2|WP_013777268.1|152670_153147_+|TRAP-transporter-small-permease
MEKVKKIFNNIEEFFVVILLLIMTVVVFWQVVCRFVLKASLPWSEELSRYILVWVTFLGASIGVKRGAHIGVEAFLMLLPKQARKLVNYLISAVCVIFCFIVFKESLSIIEMQIANAQVSPAMQIPMWWAYLAIPVGMVLMSIRFIQVSLKLKSEGEV
>NC_019954.2|WP_013777269.1|153149_154430_+|TRAP-transporter-large-permease
MSAILFGSFILFAIMGLPIAIVLGLSSVMAISMASNIPLMVVAQRMFTACDSFPLMAIPFFMMAGSLMESGGISRRLINLANKLVGSMTGGLAQVGILTCMFFAAISGSGPATVAAIGSILIPAMIEAGYDAGFAAAIMAAAGAIGVTIPPSIPMVTYGVVGGVSIGSLFMGGFGAGLVVGLSLMAAVYIISKKRGYYGEKERPTFLDILKAVKEAFWAILMPIIILGGIYGGIFTPTEAAAVAVVYGFVIGFFIYRELSVKDLPKIFVNTAVSTSVVMFIISTAQVFGWIMTSQRIPDQIAQAFINFSTSPYVILLLINLLLLVVGCFMETNAAIIILAPIFLPLIVKLGIDPILFGLIMVVNLAIGMITPPLGVNLFVACGICDMTLERISKSVLPFLIAMIVALMLITYIPGITMFLPNLLTK
>NC_019954.2|WP_013777270.1|154445_155696_+|DUF2088-domain-containing-protein
MDYPVIYRIKQRFDEYKIVNIEQAVQKELEVLKERNAIKPGMNIAVTCGSRGIANISLIIKTTIDYLKDLGARPFVIPAMGSHGGATAEGQTMVLEKLGVTPETMGVPVVSCMDVVKIGETPESVPIYMDKNAYNADGIIVINRVKPHTDFKGNIESGLLKMLAVGLGKHKGCSTIHANGLEDTIPKVARAILEKAHVIFGLAILENSKDETYKLKGLFPQDFEREERLLLKEAKSIVPKLPWDYLDILVVQEMGKTFSGTGMDTKVIGRIRVFGEEEMEKPCINKIVVLDLSDNSYGNALGVGLADITTKTLVDKIDFDVTYANTIPTTYLERGKIPVIMKDDREAIKTAMMTIGNVPLDRLKLAIIPNTLHLEEIYATKAAIEALKDKDKISVLDEGHPLNFDESGSLIVNWRR
>NC_019954.2|WP_013777271.1|155698_156079_+|hypothetical-protein
MKLMHTSLPEFKLKLQSAVIKQSPNKTFELKGIENLKSAKMQSLRTGRIEFAIQEIAEDKDIDKVEVVVMPRVPETMHTVIVKGIEKDGTCKKAILEVINIIHPTEEAELVDAKEVDDRRPPIGRH

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Crispr_ID: NC_019954_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019954_4

147551-148516

TypeIII

Consensus_repeat	Method
GTTTATAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTATAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder
NGTTTATAGCCTACCTATAAGGAATTGAAAC	CRT

14 spacers

csx20,csm3gr7,csx19,csx10gr5,cas10

The CRISPR arrays of NC_019954_4

>merge|NC_019954|4|147551-148516|PILER-CR,CRISPRCasFinder,CRT
GTTTATAGCCTACCTATAAGGAATTGAAACATGCTTCTAAAGGCGGGACTAACAATCAAATACTAGTTTATAGCCTACCTATAAGGAATTGAAACTTTAATACATATATGCCTTGGCGGGTCTGGAAAACGGCTGTTTATAGCCTACCTATAAGGAATTGAAACAATTTTCGGCTCTGATGGATTTAGCCCCGATGCTCTGTTTATAGCCTACCTATAAGGAATTGAAACTATCGTACACCTTAAAAGGTGTCTTGATAACTTTGAAGTTTATAGCCTACCTATAAGGAATTGAAACAATTCTAAAATCGTATTGGCTAAAAAACTAATATTACGTTTATAGCCTACCTATAAGGAATTGAAACAAATATGAATTTATAGATAAAATGGAGCAACAAGGCGTTTATAGCCTACCTATAAGGAATTGAAACTGTTTTTAAGTGCCCATGATTTTCCGGTCAGCGGCAGTTTATAGCCTACCTATAAGGAATTGAAACATCTTCTCGTATACATGATGGATAGCGAAAAAAGAAGTTTATAGCCTACCTATAAGGAATTGAAACGGGAAGAAACCTTACAACTTGTGCTAGAAATGCGATGTTTATAGCCTACCTATAAGGAATTGAAACGGTAATAGATAAACTGTATGGAGAGCAAAGCGAAATATGTTTATAGCCTACCTATAAGGAATTGAAACAGCTATTTAATCTGGCAGTTTTATTCGTTACTGGGTCTGTTTATAGCCTACCTATAAGGAATTGAAACGCGAGTATATCATCTCTCATTTCACTTATGGCTTGGTTTATAGCCTACCTATAAGGAATTGAAACATAGTAGTAACCGGAATAAACTCCTTCCAAAGCTCTCGTTTATAGCCTACCTATAAGGAATTGAAACACATAATTTATCCGTTTATCTATATCAACTGTAGCCATGGTTTATAGCCCTACCTATAAGGAATTGAAAC

>NC_019954|4|3|147551-148446|PILER-CR
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATGCTTCTAAAGGCGGGACTAACAATCAAATACTA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTAATACATATATGCCTTGGCGGGTCTGGAAAACGGCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	AATTTTCGGCTCTGATGGATTTAGCCCCGATGCTCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATCGTACACCTTAAAAGGTGTCTTGATAACTTTGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AATTCTAAAATCGTATTGGCTAAAAAACTAATATTAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	AAATATGAATTTATAGATAAAATGGAGCAACAAGGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGTTTTTAAGTGCCCATGATTTTCCGGTCAGCGGCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATCTTCTCGTATACATGATGGATAGCGAAAAAAGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	GGGAAGAAACCTTACAACTTGTGCTAGAAATGCGAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	GGTAATAGATAAACTGTATGGAGAGCAAAGCGAAATAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGCTATTTAATCTGGCAGTTTTATTCGTTACTGGGTCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	GCGAGTATATCATCTCTCATTTCACTTATGGCTTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAGTAGTAACCGGAATAAACTCCTTCCAAAGCTCTC
GTTTATAGCCTACCTATAAGGAATTGAAAC

>NC_019954|4|4|147551-148516|CRISPRCasFinder
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATGCTTCTAAAGGCGGGACTAACAATCAAATACTA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTAATACATATATGCCTTGGCGGGTCTGGAAAACGGCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	AATTTTCGGCTCTGATGGATTTAGCCCCGATGCTCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATCGTACACCTTAAAAGGTGTCTTGATAACTTTGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AATTCTAAAATCGTATTGGCTAAAAAACTAATATTAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	AAATATGAATTTATAGATAAAATGGAGCAACAAGGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGTTTTTAAGTGCCCATGATTTTCCGGTCAGCGGCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATCTTCTCGTATACATGATGGATAGCGAAAAAAGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	GGGAAGAAACCTTACAACTTGTGCTAGAAATGCGAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	GGTAATAGATAAACTGTATGGAGAGCAAAGCGAAATAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGCTATTTAATCTGGCAGTTTTATTCGTTACTGGGTCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	GCGAGTATATCATCTCTCATTTCACTTATGGCTTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAGTAGTAACCGGAATAAACTCCTTCCAAAGCTCTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACATAATTTATCCGTTTATCTATATCAACTGTAGCCATGG
TTTATAGCCCTACCTATAAGGAATTGAAAC

>NC_019954|4|3|147551-148515|CRT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATGCTTCTAAAGGCGGGACTAACAATCAAATACTA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTAATACATATATGCCTTGGCGGGTCTGGAAAACGGCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	AATTTTCGGCTCTGATGGATTTAGCCCCGATGCTCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATCGTACACCTTAAAAGGTGTCTTGATAACTTTGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AATTCTAAAATCGTATTGGCTAAAAAACTAATATTAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	AAATATGAATTTATAGATAAAATGGAGCAACAAGGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGTTTTTAAGTGCCCATGATTTTCCGGTCAGCGGCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATCTTCTCGTATACATGATGGATAGCGAAAAAAGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	GGGAAGAAACCTTACAACTTGTGCTAGAAATGCGAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	GGTAATAGATAAACTGTATGGAGAGCAAAGCGAAATAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGCTATTTAATCTGGCAGTTTTATTCGTTACTGGGTCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	GCGAGTATATCATCTCTCATTTCACTTATGGCTTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAGTAGTAACCGGAATAAACTCCTTCCAAAGCTCTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACATAATTTATCCGTTTATCTATATCAACTGTAGCCATG
GTTTATAGCCCTACCTATAAGGAATTGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019954.2\|WP_013777266.1\|150667_151240_+\|manganese-catalase-family-protein	unknown	unknown	gnl\|CDD\|153117
NC_019954.2\|WP_015294809.1\|157130_157493_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013777261.1\|143220_143619_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013777259.1\|140023_141640_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
NC_019954.2\|WP_013777256.1\|134295_135864_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	unknown
NC_019954.2\|WP_013777267.1\|151588_152620_+\|DctP-family-TRAP-transporter-solute-binding-subunit	unknown	unknown	gnl\|CDD\|270393
NC_019954.2\|WP_013777262.1\|143808_144111_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_019954.2\|WP_013777271.1\|155698_156079_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013777260.1\|141877_142273_+\|hypothetical-protein	csx20	xls002255_csx20_CAS-I:CAS-III	unknown
NC_019954.2\|WP_013777274.1\|157482_158013_+\|molybdopterin-binding-protein	unknown	unknown	gnl\|CDD\|214856
NC_019954.2\|WP_013777258.1\|139463_140021_+\|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl\|CDD\|274900
NC_019954.2\|WP_013777268.1\|152670_153147_+\|TRAP-transporter-small-permease	unknown	unknown	gnl\|CDD\|225632
NC_019954.2\|WP_013777257.1\|138081_139467_+\|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187857
NC_019954.2\|WP_013777270.1\|154445_155696_+\|DUF2088-domain-containing-protein	unknown	unknown	gnl\|CDD\|226392
NC_019954.2\|WP_013777265.1\|148885_150361_+\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143435
NC_019954.2\|WP_015294800.1\|135865_136525_+\|hypothetical-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
NC_019954.2\|WP_013777263.1\|144379_145669_+\|serine-dehydratase-subunit-alpha-family-protein	unknown	unknown	gnl\|CDD\|226206
NC_019954.2\|WP_013777269.1\|153149_154430_+\|TRAP-transporter-large-permease	unknown	unknown	gnl\|CDD\|224509
NC_019954.2\|WP_013777272.1\|156094_157117_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_023211309.1\|136525_138082_+\|hypothetical-protein	csx10gr5	cls000715_csx10gr5_CAS-III-D	gnl\|CDD\|131722

Protein	Function_ID	Function_description	E-value
NC_019954.2\|WP_013777266.1\|150667_151240_+\|manganese-catalase-family-protein	gnl\|CDD\|153117	cd07908, Mn_catalase_like, Manganese catalase-like protein, ferritin-like diiron-binding domain. This uncharacterized bacterial protein family has a ferritin-like domain similar to that of the manganese catalase protein of Lactobacillus plantarum and the bll3758 protein of Bradyrhizobium japonicum. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	7.42448e-62
NC_019954.2\|WP_013777274.1\|157482_158013_+\|molybdopterin-binding-protein	gnl\|CDD\|214856	smart00852, MoCF_biosynth, Probable molybdopterin binding domain. This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor. The domain is presumed to bind molybdopterin. The structure of this domain is known, and it forms an alpha/beta structure. In the known structure of Gephyrin this domain mediates trimerisation.	1.4007e-16
NC_019954.2\|WP_013777259.1\|140023_141640_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	1.25276e-76
NC_019954.2\|WP_013777262.1\|143808_144111_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.25219e-15
NC_019954.2\|WP_013777267.1\|151588_152620_+\|DctP-family-TRAP-transporter-solute-binding-subunit	gnl\|CDD\|270393	cd13675, PBP2_TRAP_SBP_like_5, Uncharacterized substrate-binding protein of the Tripartite ATP-independent Periplasmic transporter family; the type 2 periplasmic-binding protein fold. This subfamily includes uncharacterized periplasmic substrate-binding proteins similar to TRAP transport systems such as SiaP (a sialic acid binding virulence factor) and TeaA (an ectoine binding protein). TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller membrane of unknown function. The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	9.26939e-165
NC_019954.2\|WP_013777263.1\|144379_145669_+\|serine-dehydratase-subunit-alpha-family-protein	gnl\|CDD\|226206	COG3681, COG3681, L-cysteine desulfidase [Amino acid transport and metabolism].	2.77882e-110
NC_019954.2\|WP_013777268.1\|152670_153147_+\|TRAP-transporter-small-permease	gnl\|CDD\|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	8.05253e-38
NC_019954.2\|WP_013777257.1\|138081_139467_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	1.85324e-18
NC_019954.2\|WP_013777270.1\|154445_155696_+\|DUF2088-domain-containing-protein	gnl\|CDD\|226392	COG3875, COG3875, Uncharacterized conserved protein [Function unknown].	0.00113515
NC_019954.2\|WP_013777265.1\|148885_150361_+\|aldehyde-dehydrogenase	gnl\|CDD\|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
NC_019954.2\|WP_015294800.1\|135865_136525_+\|hypothetical-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.92224e-11
NC_019954.2\|WP_013777258.1\|139463_140021_+\|TIGR03984-family-CRISPR-associated-protein	gnl\|CDD\|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	9.60297e-35
NC_019954.2\|WP_013777269.1\|153149_154430_+\|TRAP-transporter-large-permease	gnl\|CDD\|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	5.06046e-135
NC_019954.2\|WP_023211309.1\|136525_138082_+\|hypothetical-protein	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	8.18086e-18

>NC_019954.2|WP_013777263.1|144379_145669_+|serine-dehydratase-subunit-alpha-family-protein
MSNELYQKAIEQVKEEMVPALGVTEPAAIALSAAKAYEVIGGEVKKVTVWVDEGVFKNGFSCAIPGTCEKGNEMAAALGVIAGKPDFGLRVLEDVTEEDVSRAKELIKEGKIEIKVKRGVSDIFIDAIVETDKGKGRAVIKDKHTNIVLVEKDGKEIFKKQLETKTSEGKAFDISRLKLKDLIDIAEHAPYEDISFILEAVRVNDELAQAGKQGEGMELGRGISDLIEEGYLKEDILTYAMAYTGYAVDARMGGVSKPAMSICGSGDHGLVATLPLIAIANKKEIPEEKLVRSILLSYLVTMYIKTFAGRLSAFCGCAVAAGTGSSAGICYLLGGNNEQIGFTIDNMAADITGIICDGGNFGCSLKAVTAASTAILSALLALKNIHIPKDSGIVGNTVEETMQNIGKIASPGMTKTNDVILDIMINRHD
>NC_019954.2|WP_013777262.1|143808_144111_-|helix-turn-helix-transcriptional-regulator
MNIGHRIKQIRIAKGLQGIQLAEKVGITNVYLSYLENGTKIPSIETLQKICDALGITLSEFFMDENANLPPEYQELIENVKVLSPKQLELLNEFLKTLRQ
>NC_019954.2|WP_013777261.1|143220_143619_+|hypothetical-protein
MKKYCIIILIVCMMLVLTACGNPNSEVVGEYDTSKLGGDFVKSSNEAYAIGANKDKMPVFKDTDKAFKQALIDYAEGFKAIQKEFNLKPINKKNWEAYKTYGWQLSADNDEEIRKQGREITQFFDIYENSFK
>NC_019954.2|WP_013777260.1|141877_142273_+|hypothetical-protein
MRQAFLLFSHQLTKSQQDELENKFKVDKIIYLPSDLQSIWSNVPPELPSIKDYLEEIFCWLKEHSKPNDIVLVQGEFGAVFLTANFCIKEGLVPIYSTTRRDVAETILDDETIQTKRNFIHVRFREFEKWD
>NC_019954.2|WP_013777259.1|140023_141640_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MEKAKLINIRKSKKGKLIGEVQFEDGKTMSIPPGAKLNVSLNNIECSIERNSGAITNITIDEKVIFSKASNSDPVSQKINKKHYTNKTTKQASNKAAQPSKAHAPYNFIPLNDTVIEGQPIPDFDCYHSEHAGLKRFNGYIECQLESITPIYIRDTYTTEEIIKKEESNEDNPDFFSPGGIARIPGSSLRGMIRTMVEIMSWGKFGFYEDKRLFYRGLADKSNLRLEYQNNMSSYDRNTRKSSYKYTIGDHIPENLKRKELIDIPESIFGKISEKQSFASRVFFEDATLMPGQNDIFVSDEPLTPKILSSPKPTTFQHYLEQPSDVTVKNLNHWNTKEAKIRGYKLYWHKDGLGWEYEGNDEEKAKNKRILTKIKPIKPGIKFKYRIRFENLSQEEIGAILFAIDLPENCYHKIGMGKPLGLGTIKIRPALFLINRESRYTNLFENENWNLGVEESNIQKFKDAFEQYVLNQVNKLENSDLSSLWNHERMKHLKVILDFENTKLKGWKQETDYMELKEFKNRPVLSKPLEVYNKFTTN
>NC_019954.2|WP_013777258.1|139463_140021_+|TIGR03984-family-CRISPR-associated-protein
MNGLKLANIKSTSKPMELNIASWQDLQKNINENFKEKSYAVVYLDYKVLIGKINEKNLKFYNDEVFDPKFIVKMRVFNEEKELLLWRRDEYKFEGRMRLDNEGDNIQYFVEVDQVLWGNPKSINNEWTVLKEARGTEIYIPYLYKPEYSSSKRLAIRTRNYVGYNEIGQAGYTDCRFVSFCEGGK
>NC_019954.2|WP_013777257.1|138081_139467_+|hypothetical-protein
MDNAKVTGRFLIRGKLDLESPLLIGTGEKGYIDISVQKDDNGIPYIPASSMRGVLRHYFFNNLTIQGTDKTQIEYFWGSSKNQDDKDTYQSSFILEDLYALNKPNIVVRDGIKIDNKRGIAEDEKKFDYEVVEPGAEFGFNAEVVLRECFSKEMFLKIISTLISALENGQISLGSMTTKGFGRCRLSECKVYEYDFTQGTNKTKDVILWLKGESTEEQLITLDLNEIFLPKKNKFSLKATFNIRNSLIVKAYTGMPKEPDSIHIISAGKDILPGTSLKGALRARAVKIINTLEGQSDELVKELFGWASDEASDKNKKIKSRLILDEAYIQNSVKETQFRTKIDRFTGGVIKTALFDSTPVWSGKDNAKVTINIEINDCKNWEAGLVMLLLKDLWTGDLAAGGEKNIGRGTFEGQSAEIYFNGNHYIIEQRGDKLRVNCGKDELENLVSAFVEKCKSGRAGV
>NC_019954.2|WP_023211309.1|136525_138082_+|hypothetical-protein
MAYLKITINLLSPIILSADVPDNNLTETFDYIPASSLIGLFAAKYISQEHLEYAHNNTNFYKWFLKGDLVFTNAYISEKDDYDEIDMLPTPLCIKKQKKGERILNILLNTEDEQTVFISPYSYIERSTIKTGELAKKINFHHMRDRLRGHTKDEAMFNYEALMPGQIFKGEIYGDSTTLREFRKTFGEKIIGRLGKSRNTEYGEVEISLSKIINEDIDALTDEDLEDEDYILLTFISPCILVNENGFPDPSLPNLKCYLENIWGKDSFEIENCVMRTTSIENYISVWKMKRPIETAISAGSTVKLVFKNNLPFENIKNGFEKMANDGIGERRNEGFGRIKLNMATAEEYYKKTIKPNQNKPESKVPQGAKQIFENVIQNMFKEEFERKAYEDAAGFSCLPSNSLLGKLGLILSKCQKEEEFKKSIDELRNNAKSQLEDCRNKTKRCNLYEYIKNFDTTKIIESIYNDITKADYLKLTKISEYNVKDEKELLLELWKIYFGVFFRRMRQRQKVAKKEVL
>NC_019954.2|WP_015294800.1|135865_136525_+|hypothetical-protein
MSEYKITIKLESNCMLGAGEGWGSVIDADIVFDNVGLPYLPARRLKGCLRESAKEVLEMMECAGIKKFESQIIDKVFGCSGDATGAGIVFNNLYLPNYKDVYDWCKWALQECNSAVSPEIIVNSFTSIKQQTSINNEGIADDKSLRTFRVLKRGIEFEGAVNIKEEDKEAVDLLALACLNLRYIGTMRNRGYGKIVCRFKKGNEDLSQSCIEQIEREAI
>NC_019954.2|WP_013777256.1|134295_135864_+|hypothetical-protein
MSKVTAILADTVSIQKYVYSSNRLKENIGASSIIANIYKESLANTLEKTLEHGVSLDEWEKQPETIAIKNSNTDFEVGYIGGGNALLFFNNEATAKEFISEWTRSLLLEAPSLNVAFAISEFNIDNFQNEMKNLFKQLEINKSKYFPQTFLPKHGITADCPYSGLSAEVYKPGTNDEKGAYISSASYVKYKHIDIDDAKVEVERISNGKFSLTTNIEKLGQTKGQNHIAIVHIDGNSMAEHFKSCENLVAIRKLSKRLKDIMQSVYEEFLNYIFEQMDLLLSDESGFNIQLENGKYIIPFRPILREGDDITFITDGRLGIPFAQKYLELMSDKTLYNENKLSACAGVAIIKTKYPFFRGYNLTEELCQSAKREARENKGTSWLDFHISYGGFSGTLEGIRKNKYTTSSGQLHFGPYLVASSDISNEKNIFHLKRGIKTFKNKEEWPRSKVKEFREYLTLGKSASQQFIDEARFKGRKLYGFKETSKTYNINVWQDGFTPYFDMIELMDLIPEYFLAETRQVK
>NC_019954.2|WP_013777265.1|148885_150361_+|aldehyde-dehydrogenase
MNKPIDKNYQLLIGGRWVDAKDGETFETNNPANGELLATCANAGKEDVDEAVKAAWKAFETWKDVSAQEKSGILLKIADLIDENAEKLAMIETLDNGKPIRETRNIDVPLSSDHFRYFAGAIRAEEGQAVMIDKNTLSIILREPIGVVGQIIPWNFPLLMAAWKLAPALAAGCTVVIKPSSSTPLSILELGKLINDVLPPGVVNIVTGSGATTGNYMLEHPGFRKLAFTGSTEVGYSIAEAAAKKLIPSTLELGGKSANIYFPDCPWEKAIEGVQLGILFNQGQVCCAGSRVFVHEDIYEEFLAECVEAFKKIKVGLPWEEDTIMGTQINEGQLKKILNYIEIGKQEGARLACGGSRITENGLDKGCFMQPTIFADVDNKMRIAQEEIFGPVACFLKFKDEEEVIKMANDSEYGLGGAVWTKDINRALKVARGIETGRMWINDYNNLPAHTPFGGYKKSGIGRETHHMMLDHYTQKKNIMISMNENKAGLY
>NC_019954.2|WP_013777266.1|150667_151240_+|manganese-catalase-family-protein
MSEDFVDLKGCKTPETYNKCAYPAPYPEIKVARENPYYGKLLLEDYAGRAGELTAVNQYIYHHFVLEPEYEEVAELLSCVALVEMHHMEILADTILKLGVDPRQRTIATNEVEIYWDAGFVYYGTVLCDMITANIAGEWAAISNYRKHQQMINDLYVKKILERIILDEIYHVQLFSQVTEKYCKPNIKKE
>NC_019954.2|WP_013777267.1|151588_152620_+|DctP-family-TRAP-transporter-solute-binding-subunit
MSKKNLALLLISLLIIGLLAGCGGGQQNGNDAAPSGNQDKGGTITIKVGHVLAPTHPYTLGLQKFAELVDEKTDGKIKVEVFHSSQLGNERDMVEALQLGTQEMTLVSTAPLASFTKQFLVFDLPFVFKDTESARKVLDSELGQGLLNSLESQGIMGLCYFENGFRHVTNSKHPINKPEDLKGIKIRTMENPIHMATFKVMGADPTPMAFGELFTALQQKTIDAQENPLPIIETSKFYEVQEYLSLTGHFYAPAPLLISKSFFEGLAPELQAALKEAAIEARDYERGLLDDMNAKLVEELKEKGMKVNEPDKTLFVEAVQSVYKQFESDITPELIQKVVDAQK
>NC_019954.2|WP_013777268.1|152670_153147_+|TRAP-transporter-small-permease
MEKVKKIFNNIEEFFVVILLLIMTVVVFWQVVCRFVLKASLPWSEELSRYILVWVTFLGASIGVKRGAHIGVEAFLMLLPKQARKLVNYLISAVCVIFCFIVFKESLSIIEMQIANAQVSPAMQIPMWWAYLAIPVGMVLMSIRFIQVSLKLKSEGEV
>NC_019954.2|WP_013777269.1|153149_154430_+|TRAP-transporter-large-permease
MSAILFGSFILFAIMGLPIAIVLGLSSVMAISMASNIPLMVVAQRMFTACDSFPLMAIPFFMMAGSLMESGGISRRLINLANKLVGSMTGGLAQVGILTCMFFAAISGSGPATVAAIGSILIPAMIEAGYDAGFAAAIMAAAGAIGVTIPPSIPMVTYGVVGGVSIGSLFMGGFGAGLVVGLSLMAAVYIISKKRGYYGEKERPTFLDILKAVKEAFWAILMPIIILGGIYGGIFTPTEAAAVAVVYGFVIGFFIYRELSVKDLPKIFVNTAVSTSVVMFIISTAQVFGWIMTSQRIPDQIAQAFINFSTSPYVILLLINLLLLVVGCFMETNAAIIILAPIFLPLIVKLGIDPILFGLIMVVNLAIGMITPPLGVNLFVACGICDMTLERISKSVLPFLIAMIVALMLITYIPGITMFLPNLLTK
>NC_019954.2|WP_013777270.1|154445_155696_+|DUF2088-domain-containing-protein
MDYPVIYRIKQRFDEYKIVNIEQAVQKELEVLKERNAIKPGMNIAVTCGSRGIANISLIIKTTIDYLKDLGARPFVIPAMGSHGGATAEGQTMVLEKLGVTPETMGVPVVSCMDVVKIGETPESVPIYMDKNAYNADGIIVINRVKPHTDFKGNIESGLLKMLAVGLGKHKGCSTIHANGLEDTIPKVARAILEKAHVIFGLAILENSKDETYKLKGLFPQDFEREERLLLKEAKSIVPKLPWDYLDILVVQEMGKTFSGTGMDTKVIGRIRVFGEEEMEKPCINKIVVLDLSDNSYGNALGVGLADITTKTLVDKIDFDVTYANTIPTTYLERGKIPVIMKDDREAIKTAMMTIGNVPLDRLKLAIIPNTLHLEEIYATKAAIEALKDKDKISVLDEGHPLNFDESGSLIVNWRR
>NC_019954.2|WP_013777271.1|155698_156079_+|hypothetical-protein
MKLMHTSLPEFKLKLQSAVIKQSPNKTFELKGIENLKSAKMQSLRTGRIEFAIQEIAEDKDIDKVEVVVMPRVPETMHTVIVKGIEKDGTCKKAILEVINIIHPTEEAELVDAKEVDDRRPPIGRH
>NC_019954.2|WP_013777272.1|156094_157117_+|hypothetical-protein
MGELTVRFIKQGTGPKQGAPINIALIDKRDVEASGKSLEDVIHMVAKVVGGPVGINVFDMDAVTTTSDGLVVEGAIITMAAGDIGKVHKEFGILHMEEMEVTHELIKEEPHLVQWEKYYKGKKLFRGPDPNKKLIPVHNVVMTGKAVNNNSATEMMNAVTMEEILLPILGQLQIMKDEPIVFGLTGEVISVGIGMTVAEKYGRVFPTRQFRAGDTAHGSGEYAKTLKANIPCIVAPKSVLAGYIIQALDAGMIPGLHIGCSPAVLAVANAKGAKIALDKITEKAKIELKSVGVDVDHMKPAVSLMTNKEIIEKADDIIPGVVDPVLISSSNIVTKLTLSI
>NC_019954.2|WP_015294809.1|157130_157493_+|hypothetical-protein
MDNQVIVFVDKTYVRITGIQIKGLKPFELEQTLKNTLQRPIRVIGVTGSAIEMDIYGMEPEAVYKDEKGIIKAISTVSGITAADVIKIAQAERSVEVSVEKFPKGKYSGCARERWLNFDK
>NC_019954.2|WP_013777274.1|157482_158013_+|molybdopterin-binding-protein
MTSKAIIIPTGDEILNGTVVDTNSPAIMALILERFPGCEVTRITPSVDNETTIITKLKRAIEEKADLIFIIGGSGGGHRFIPNAARDFTHTAILKMFPNSCFKEIYGKNGHLWSKLIAAKESNSLLVNVPGPYVEAVAAAEAALDSILKGETDPQIIVERTSEAVSRQYPSGGEIK

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Crispr_ID: NC_019954_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019954_5

237246-240316

Orphan

Consensus_repeat	Method
GTTTATAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTATAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder
GTTTATAGCCTACCTATAAGGAATTGAAAC	CRT

45 spacers

The CRISPR arrays of NC_019954_5

>merge|NC_019954|5|237246-240316|PILER-CR,CRISPRCasFinder,CRT
GTTTATAGCCTACCTATAAGGAATTGAAACGATGTTAACTTTATAAACATAAATGCAGACGAACTGTTTATAGCCTACCTATAAGGAATTGAAACCATTTGAGGATCTGGAAGGGCTGACCTTAGCCTCCGGAGGTTTATAGCCTACCTATAAGGAATTGAAACAGAAACGACACGACAAATTATGAAAGAAAGCAATTTGTTTATAGCCTACCTATAAGGAATTGAAACCGGCTAACCGCATTATAATACGTGATGCAAGTGGCCGGGTTTATAGCCTACCTATAAGGAATTGAAACGTTGATGAACATTCCATAGATAGTTTGCAATTTATGTGTGTTTATAGCCTACCTATAAGGAATTGAAACATTGGAGAAACTTTTAATAGAGCATAAAAGGACTGAGTTTATAGCCTACCTATAAGGAATTGAAACAAAAAAGATATAGTTTTTTAGAAGTCTTGAATGATGAAGGGTTTATAGCCTACCTATAAGGAATTGAAACTTTGATTGAGGATATATTCCTTGCTAATGATATAGCTTTTGTTTATAGCCTACCTATAAGGAATTGAAACCCATAATCAGTAACTATTTCTCTGCTAGCATTTCTTGTTTATAGCCTACCTATAAGGAATTGAAACTATTCCATTTTGTGTTTTGTATAGTTACCAAATCACCAAGCGTTTATAGCCTACCTATAAGGAATTGAAACTTGCTTTGATGAGGTAGCACTATTTTTAGAAGTTGAGGTTTATAGCCTACCTATAAGGAATTGAAACGTCACAATTTGGGCAATACCATGTTTCCATAGGCGTGGTTTATAGCCTACCTATAAGGAATTGAAACAGGCTTGCCCAAAAAGCGGAATATTATTTGTACTTTGTTTATAGCCTACCTATAAGGAATTGAAACTTTGCGGGTAAACAATAAGGCAGAAAACACAATAACGTTTATAGCCTACCTATAAGGAATTGAAACATGGTGAAGTTATAGAAGATGATACTAGTAGCACTAAGTTTATAGCCTACCTATAAGGAATTGAAACCATTTATTGCAAACTATGCACTTTCCTTTGCTTCAAGTTTATAGCCTACCTATAAGGAATTGAAACAACTCTTCTAAAAAATCATTAAAACTAACTTTTTTTACGTTTATAGCCTACCTATAAGGAATTGAAACTTGTAATAACAATATAATGATGCAAATAAATAAAGCGTTTATAGCCTACCTATAAGGAATTGAAACATGAAGAAGCAGAGATTGACAAGCCAAGCTATGCAAGTTTATAGCCTACCTATAAGGAATTGAAACTACCTTGGAACTGTTCGCTCATGATTATAATAATTCGTTTATAGCCTACCTATAAGGAATTGAAACTAAGACTCAATCCAACTTTCCAAAAATTCACGCAAAGGTTTATAGCCTACCTATAAGGAATTGAAACTGAAACCCTTTCTTCATTTTTGGCCAATGAGCTTCTAGCGTTTATAGCCTACCTATAAGGAATTGAAACGTCGAAGAGGAGGTGGCGAATTGACGAGGGAAGAGCTGTTTATAGCCTACCTATAAGGAATTGAAACGCAGCAAGTTTTGCGGCACCACTTTTGGCGATATTGAATGTTTATAGCCTACCTATAAGGAATTGAAACTGCCTATCCACTGTGGAAATGGCTGCTCTTCGGGCATTTCGTTTATAGCCTACCTATAAGGAATTGAAACTGGAATATATGGTCCGGTATATGTTGATCTGTAGGAAGTTTATAGCCTACCTATAAGGAATTGAAACCAGGACTATATTGGAAATATTCAAAGATGCACTTATTGGTTTATAGCCTACCTATAAGGAATTGAAACTGATGTAATCATTGATTTCTTTAGGATTAAAACCACATGTTTATAGCCTACCTATAAGGAATTGAAACTCGGGTCATCAGACTGATCATCCAGTGTTGCCACCGTTTATAGCCTACCTATAAGGAATTGAAACCACTAATGTTGGATGAATCATCACAGATACAAAATGAAACGTTTATAGCCTACCTATAAGGAATTGAAACATAACAAGATTGAATTCAGTCAAAAGGAAATGGATAAGGCAGTTTATAGCCTACCTATAAGGAATTGAAACTGAAGCTTGATGACATGAAGAATATCCTTAAAACCCGTTTATAGCCTACCTATAAGGAATTGAAACACTGGTACATGGCCGCAGTCTGTTCCTGTATGCTGGGTTTATAGCCTACCTATAAGGAATTGAAACTGGACTACCAGACACAAAGAGATCGCGCCGATAAGGCCGAGTTTATAGCCTACCTATAAGGAATTGAAACTTGTAAACACGCCCATCTCTAGTGACAGTATATGTCTTTGTTTATAGCCTACCTATAAGGAATTGAAACTGGAGGTGTTGTAAATGGCATACAAAGGCCAACCCGGTTTATAGCCTACCTATAAGGAATTGAAACCTTTGCACGAGTATGAAAACAGCCTCATCTTGCTCCCGTTTATAGCCTACCTATAAGGAATTGAAACCAGAATACTACCTCTCCTTGCCAATCTTGTTTTAAACCATCGTTTATAGCCTACCTATAAGGAATTGAAACCATGGGGAGTGCTGGGCAAGACTTCGTAGACGAAGGTTTATAGCCTACCTATAAGGAATTGAAACGTTGATAATTGTATTTTTAATTTACTGTTTATCCTTGTGTTTATAGCCTACCTATAAGGAATTGAAACACGACAGACAGGATATAGAGGATTTGGTTACACGTGGTTTATAGCCTACCTATAAGGAATTGAAACCTGAAAGTAGGAAGCCGACCGGCATAAACAAAGCCAGTTTATAGCCTACCTATAAGGAATTGAAACAGGATAAAAGATAACTGGCAAGTGTTTCCTAGCAGGGGTTTATAGCCTACCTATAAGGAATTGAAACCTATCTCCTGGTCGCCTTCAGCCAAGGCGAACATCCTTGTTTATAGCCTACCTATAAGGAATTGAAACAGACATGGCATTGATTTCTTGGGATTCAGGACCTTTATGGTTTATAGCCTACCTATAAGGAATTGAAACT

>NC_019954|5|4|237246-240246|PILER-CR
GTTTATAGCCTACCTATAAGGAATTGAAAC	GATGTTAACTTTATAAACATAAATGCAGACGAACT
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATTTGAGGATCTGGAAGGGCTGACCTTAGCCTCCGGAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGAAACGACACGACAAATTATGAAAGAAAGCAATTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	CGGCTAACCGCATTATAATACGTGATGCAAGTGGCCGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTTGATGAACATTCCATAGATAGTTTGCAATTTATGTGT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATTGGAGAAACTTTTAATAGAGCATAAAAGGACTGA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AAAAAAGATATAGTTTTTTAGAAGTCTTGAATGATGAAGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTGATTGAGGATATATTCCTTGCTAATGATATAGCTTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	CCATAATCAGTAACTATTTCTCTGCTAGCATTTCTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATTCCATTTTGTGTTTTGTATAGTTACCAAATCACCAAGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTGCTTTGATGAGGTAGCACTATTTTTAGAAGTTGAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTCACAATTTGGGCAATACCATGTTTCCATAGGCGTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGGCTTGCCCAAAAAGCGGAATATTATTTGTACTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTGCGGGTAAACAATAAGGCAGAAAACACAATAAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATGGTGAAGTTATAGAAGATGATACTAGTAGCACTAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATTTATTGCAAACTATGCACTTTCCTTTGCTTCAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AACTCTTCTAAAAAATCATTAAAACTAACTTTTTTTAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTGTAATAACAATATAATGATGCAAATAAATAAAGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATGAAGAAGCAGAGATTGACAAGCCAAGCTATGCAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TACCTTGGAACTGTTCGCTCATGATTATAATAATTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TAAGACTCAATCCAACTTTCCAAAAATTCACGCAAAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGAAACCCTTTCTTCATTTTTGGCCAATGAGCTTCTAGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTCGAAGAGGAGGTGGCGAATTGACGAGGGAAGAGCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	GCAGCAAGTTTTGCGGCACCACTTTTGGCGATATTGAAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGCCTATCCACTGTGGAAATGGCTGCTCTTCGGGCATTTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGGAATATATGGTCCGGTATATGTTGATCTGTAGGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	CAGGACTATATTGGAAATATTCAAAGATGCACTTATTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGATGTAATCATTGATTTCTTTAGGATTAAAACCACAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCGGGTCATCAGACTGATCATCCAGTGTTGCCACC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CACTAATGTTGGATGAATCATCACAGATACAAAATGAAAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAACAAGATTGAATTCAGTCAAAAGGAAATGGATAAGGCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGAAGCTTGATGACATGAAGAATATCCTTAAAACCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACTGGTACATGGCCGCAGTCTGTTCCTGTATGCTGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGGACTACCAGACACAAAGAGATCGCGCCGATAAGGCCGA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTGTAAACACGCCCATCTCTAGTGACAGTATATGTCTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGGAGGTGTTGTAAATGGCATACAAAGGCCAACCCG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CTTTGCACGAGTATGAAAACAGCCTCATCTTGCTCCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CAGAATACTACCTCTCCTTGCCAATCTTGTTTTAAACCATC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATGGGGAGTGCTGGGCAAGACTTCGTAGACGAAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTTGATAATTGTATTTTTAATTTACTGTTTATCCTTGT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACGACAGACAGGATATAGAGGATTTGGTTACACGTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CTGAAAGTAGGAAGCCGACCGGCATAAACAAAGCCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGGATAAAAGATAACTGGCAAGTGTTTCCTAGCAGGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CTATCTCCTGGTCGCCTTCAGCCAAGGCGAACATCCTT
GTTTATAGCCTACCTATAAGGAATTGAAAC

>NC_019954|5|5|237246-240316|CRISPRCasFinder
GTTTATAGCCTACCTATAAGGAATTGAAAC	GATGTTAACTTTATAAACATAAATGCAGACGAACT
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATTTGAGGATCTGGAAGGGCTGACCTTAGCCTCCGGAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGAAACGACACGACAAATTATGAAAGAAAGCAATTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	CGGCTAACCGCATTATAATACGTGATGCAAGTGGCCGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTTGATGAACATTCCATAGATAGTTTGCAATTTATGTGT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATTGGAGAAACTTTTAATAGAGCATAAAAGGACTGA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AAAAAAGATATAGTTTTTTAGAAGTCTTGAATGATGAAGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTGATTGAGGATATATTCCTTGCTAATGATATAGCTTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	CCATAATCAGTAACTATTTCTCTGCTAGCATTTCTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATTCCATTTTGTGTTTTGTATAGTTACCAAATCACCAAGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTGCTTTGATGAGGTAGCACTATTTTTAGAAGTTGAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTCACAATTTGGGCAATACCATGTTTCCATAGGCGTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGGCTTGCCCAAAAAGCGGAATATTATTTGTACTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTGCGGGTAAACAATAAGGCAGAAAACACAATAAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATGGTGAAGTTATAGAAGATGATACTAGTAGCACTAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATTTATTGCAAACTATGCACTTTCCTTTGCTTCAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AACTCTTCTAAAAAATCATTAAAACTAACTTTTTTTAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTGTAATAACAATATAATGATGCAAATAAATAAAGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATGAAGAAGCAGAGATTGACAAGCCAAGCTATGCAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TACCTTGGAACTGTTCGCTCATGATTATAATAATTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TAAGACTCAATCCAACTTTCCAAAAATTCACGCAAAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGAAACCCTTTCTTCATTTTTGGCCAATGAGCTTCTAGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTCGAAGAGGAGGTGGCGAATTGACGAGGGAAGAGCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	GCAGCAAGTTTTGCGGCACCACTTTTGGCGATATTGAAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGCCTATCCACTGTGGAAATGGCTGCTCTTCGGGCATTTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGGAATATATGGTCCGGTATATGTTGATCTGTAGGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	CAGGACTATATTGGAAATATTCAAAGATGCACTTATTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGATGTAATCATTGATTTCTTTAGGATTAAAACCACAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCGGGTCATCAGACTGATCATCCAGTGTTGCCACC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CACTAATGTTGGATGAATCATCACAGATACAAAATGAAAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAACAAGATTGAATTCAGTCAAAAGGAAATGGATAAGGCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGAAGCTTGATGACATGAAGAATATCCTTAAAACCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACTGGTACATGGCCGCAGTCTGTTCCTGTATGCTGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGGACTACCAGACACAAAGAGATCGCGCCGATAAGGCCGA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTGTAAACACGCCCATCTCTAGTGACAGTATATGTCTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGGAGGTGTTGTAAATGGCATACAAAGGCCAACCCG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CTTTGCACGAGTATGAAAACAGCCTCATCTTGCTCCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CAGAATACTACCTCTCCTTGCCAATCTTGTTTTAAACCATC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATGGGGAGTGCTGGGCAAGACTTCGTAGACGAAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTTGATAATTGTATTTTTAATTTACTGTTTATCCTTGT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACGACAGACAGGATATAGAGGATTTGGTTACACGTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CTGAAAGTAGGAAGCCGACCGGCATAAACAAAGCCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGGATAAAAGATAACTGGCAAGTGTTTCCTAGCAGGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CTATCTCCTGGTCGCCTTCAGCCAAGGCGAACATCCTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGACATGGCATTGATTTCTTGGGATTCAGGACCTTTATG
GTTTATAGCCTACCTATAAGGAATTGAAACT

>NC_019954|5|4|237246-240315|CRT
GTTTATAGCCTACCTATAAGGAATTGAAAC	GATGTTAACTTTATAAACATAAATGCAGACGAACT
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATTTGAGGATCTGGAAGGGCTGACCTTAGCCTCCGGAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGAAACGACACGACAAATTATGAAAGAAAGCAATTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	CGGCTAACCGCATTATAATACGTGATGCAAGTGGCCGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTTGATGAACATTCCATAGATAGTTTGCAATTTATGTGT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATTGGAGAAACTTTTAATAGAGCATAAAAGGACTGA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AAAAAAGATATAGTTTTTTAGAAGTCTTGAATGATGAAGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTGATTGAGGATATATTCCTTGCTAATGATATAGCTTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	CCATAATCAGTAACTATTTCTCTGCTAGCATTTCTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATTCCATTTTGTGTTTTGTATAGTTACCAAATCACCAAGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTGCTTTGATGAGGTAGCACTATTTTTAGAAGTTGAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTCACAATTTGGGCAATACCATGTTTCCATAGGCGTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGGCTTGCCCAAAAAGCGGAATATTATTTGTACTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTTGCGGGTAAACAATAAGGCAGAAAACACAATAAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATGGTGAAGTTATAGAAGATGATACTAGTAGCACTAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATTTATTGCAAACTATGCACTTTCCTTTGCTTCAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AACTCTTCTAAAAAATCATTAAAACTAACTTTTTTTAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTGTAATAACAATATAATGATGCAAATAAATAAAGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATGAAGAAGCAGAGATTGACAAGCCAAGCTATGCAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TACCTTGGAACTGTTCGCTCATGATTATAATAATTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TAAGACTCAATCCAACTTTCCAAAAATTCACGCAAAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGAAACCCTTTCTTCATTTTTGGCCAATGAGCTTCTAGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTCGAAGAGGAGGTGGCGAATTGACGAGGGAAGAGCT
GTTTATAGCCTACCTATAAGGAATTGAAAC	GCAGCAAGTTTTGCGGCACCACTTTTGGCGATATTGAAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGCCTATCCACTGTGGAAATGGCTGCTCTTCGGGCATTTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGGAATATATGGTCCGGTATATGTTGATCTGTAGGAA
GTTTATAGCCTACCTATAAGGAATTGAAAC	CAGGACTATATTGGAAATATTCAAAGATGCACTTATTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGATGTAATCATTGATTTCTTTAGGATTAAAACCACAT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCGGGTCATCAGACTGATCATCCAGTGTTGCCACC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CACTAATGTTGGATGAATCATCACAGATACAAAATGAAAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAACAAGATTGAATTCAGTCAAAAGGAAATGGATAAGGCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGAAGCTTGATGACATGAAGAATATCCTTAAAACCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACTGGTACATGGCCGCAGTCTGTTCCTGTATGCTGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGGACTACCAGACACAAAGAGATCGCGCCGATAAGGCCGA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTGTAAACACGCCCATCTCTAGTGACAGTATATGTCTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGGAGGTGTTGTAAATGGCATACAAAGGCCAACCCG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CTTTGCACGAGTATGAAAACAGCCTCATCTTGCTCCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CAGAATACTACCTCTCCTTGCCAATCTTGTTTTAAACCATC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CATGGGGAGTGCTGGGCAAGACTTCGTAGACGAAG
GTTTATAGCCTACCTATAAGGAATTGAAAC	GTTGATAATTGTATTTTTAATTTACTGTTTATCCTTGT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACGACAGACAGGATATAGAGGATTTGGTTACACGTG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CTGAAAGTAGGAAGCCGACCGGCATAAACAAAGCCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGGATAAAAGATAACTGGCAAGTGTTTCCTAGCAGGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	CTATCTCCTGGTCGCCTTCAGCCAAGGCGAACATCCTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	AGACATGGCATTGATTTCTTGGGATTCAGGACCTTTATG
GTTTATAGCCTACCTATAAGGAATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019954.2\|WP_013777370.1\|256466_256655_-\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013777367.1\|248373_249855_+\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NC_019954.2\|WP_023211328.1\|235404_236751_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240543
NC_019954.2\|WP_013777362.1\|243200_243881_+\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl\|CDD\|133470
NC_019954.2\|WP_013777361.1\|242182_243094_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NC_019954.2\|WP_041591468.1\|256739_257744_-\|AIR-synthase-family-protein	unknown	unknown	gnl\|CDD\|100037
NC_019954.2\|WP_013777366.1\|247879_248356_+\|transcription-elongation-factor-GreA	unknown	unknown	gnl\|CDD\|234693
NC_019954.2\|WP_013777357.1\|232643_233033_+\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NC_019954.2\|WP_013777356.1\|232189_232624_+\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NC_019954.2\|WP_013777354.1\|230586_231381_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NC_019954.2\|WP_013777355.1\|231394_232126_+\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NC_019954.2\|WP_013777369.1\|255984_256443_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239645
NC_019954.2\|WP_013777352.1\|228910_229747_+\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|275313
NC_019954.2\|WP_013777363.1\|244073_244985_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NC_019954.2\|WP_013777358.1\|233157_234207_+\|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE	unknown	unknown	gnl\|CDD\|180835
NC_019954.2\|WP_013777365.1\|246207_247428_-\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|132848
NC_019954.2\|WP_013777368.1\|255397_255865_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_019954.2\|WP_013777359.1\|234214_235408_+\|[FeFe]-hydrogenase-H-cluster-maturation-GTPase-HydF	unknown	unknown	gnl\|CDD\|274853
NC_019954.2\|WP_013777350.1\|227569_228517_+\|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl\|CDD\|235359
NC_019954.2\|WP_013777351.1\|228532_228865_+\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522

Protein	Function_ID	Function_description	E-value
NC_019954.2\|WP_013777367.1\|248373_249855_+\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NC_019954.2\|WP_023211328.1\|235404_236751_-\|MATE-family-efflux-transporter	gnl\|CDD\|240543	cd13138, MATE_yoeA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	3.64499e-122
NC_019954.2\|WP_013777362.1\|243200_243881_+\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl\|CDD\|133470	cd01415, SAICAR_synt_PurC, bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase. A subfamily of SAICAR synthetases represented by the Thermotoga maritima (Tm) enzyme and E. coli PurC. SAICAR synthetase catalyzes the seventh step of the de novo biosynthesis of purine nucleotides (also reported as eighth step). It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.	5.27122e-52
NC_019954.2\|WP_013777361.1\|242182_243094_+\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.55481e-25
NC_019954.2\|WP_041591468.1\|256739_257744_-\|AIR-synthase-family-protein	gnl\|CDD\|100037	cd06061, PurM-like1, AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two conserved domains and seem to dimerize. The N-terminal domain forms the dimer interface and is a putative ATP binding domain.	2.62122e-129
NC_019954.2\|WP_013777366.1\|247879_248356_+\|transcription-elongation-factor-GreA	gnl\|CDD\|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	3.33479e-69
NC_019954.2\|WP_013777357.1\|232643_233033_+\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	3.12559e-77
NC_019954.2\|WP_013777356.1\|232189_232624_+\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.50804e-99
NC_019954.2\|WP_013777354.1\|230586_231381_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.06455e-48
NC_019954.2\|WP_013777355.1\|231394_232126_+\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	6.07375e-139
NC_019954.2\|WP_013777369.1\|255984_256443_+\|NUDIX-hydrolase	gnl\|CDD\|239645	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most preferred substrate, hydrolyzes to produce two ATP molecules, which is a novel hydrolysis mode for Ap6A. These results indicate that Ap6A hydrolase is a diadenosine polyphosphate hydrolase. It requires the presence of a divalent cation, such as Mn2+, Mg2+, Zn2+, and Co2+, for activity. Members of the Nudix superfamily are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site.	2.6638e-38
NC_019954.2\|WP_013777352.1\|228910_229747_+\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|275313	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	3.85581e-178
NC_019954.2\|WP_013777363.1\|244073_244985_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	9.24389e-145
NC_019954.2\|WP_013777358.1\|233157_234207_+\|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE	gnl\|CDD\|180835	PRK07094, PRK07094, biotin synthase; Provisional.	7.1476e-171
NC_019954.2\|WP_013777365.1\|246207_247428_-\|patatin-like-phospholipase-family-protein	gnl\|CDD\|132848	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli. Patatin-like phospholipase similar to Z1214 protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	3.15524e-63
NC_019954.2\|WP_013777368.1\|255397_255865_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.32054e-19
NC_019954.2\|WP_013777359.1\|234214_235408_+\|[FeFe]-hydrogenase-H-cluster-maturation-GTPase-HydF	gnl\|CDD\|274853	TIGR03918, hydrogenase_maturation_GTPase_HydF, [FeFe] hydrogenase H-cluster maturation GTPase HydF. This model describes the family of the [Fe] hydrogenase maturation protein HypF as characterized in Chlamydomonas reinhardtii and found, in an operon with radical SAM proteins HydE and HydG, in numerous bacteria. It has GTPase activity, can bind an 4Fe-4S cluster, and is essential for hydrogenase activity. [Protein fate, Protein modification and repair].	0
NC_019954.2\|WP_013777350.1\|227569_228517_+\|DNA-directed-RNA-polymerase-subunit-alpha	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	0
NC_019954.2\|WP_013777351.1\|228532_228865_+\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	1.59899e-60

>NC_019954.2|WP_023211328.1|235404_236751_-|MATE-family-efflux-transporter
MTVGTPWKRIVEFSIPMLVGNIAQQLYNTVDSIVIGRYVGDNALAAVGSALPIFNFLLVFFVAVSTGAGIMVSQYFGAKDREKLSRSIGACITLTAIVATIIMIIGPIVVRPMLVLINTPESIIDWCASYLLILLVGNWGFSYFNILSGILRGLGDSLSALMFLLISTVLNIFLDIWFVAGLNMGVPGVALATVIAQVISAVLCAMKLKTMDYVFDLNLNMLKPKKEYVVQLLKLGLPSGLTQVIFSLAMITVQSLTNTFGEMIIACNVIVMRVDGFAMMPNFTFGVAMTTFAGQNVGAKKMDRVEEGTRQGLAIAVGVSIVITIIILIFGRYLMDIFTDTAELVDLSMKMMRILAVGYVAMAVTQVLSGVMRGAGDTMTPMWISLITTIFLRVPIAYGIAYLTRSAQYPNGRPESVFVSLLIAWVSGAVITSIFYKKGNWREKVLLS
>NC_019954.2|WP_013777359.1|234214_235408_+|[FeFe]-hydrogenase-H-cluster-maturation-GTPase-HydF
MNDTPRANRLHIGLFGRRNSGKSSLINAITGQEIALVSDFPGTTTDPVYKAMELLPIGPVVFIDTAGLDDVGDLGELRIKKTLEVMDKTDIALVVFSTENLDFSLEKRWCQELRSRNIPIIGVVNKIDKRDVDIKDLTKEFDFPFIKVSANKRENIGKLKEMIHQNAPMDFELSTLVGDIITPKSLVVLVTPQDIQAPKNRLILPQVQTIRDILDNNCMALVAKETELLDLLNCLNKKPALVITDSQVFHIVSKIVPEDIPLTSFSIIMSRYKGELSTLVRGAKAMDELKPNDRVLIEEACTHHPLENDIGRQKLPALLENKAGGKLQIEIKVGGDFPEDLTPYALILHCGACMLNRKQMLTRIIRAREQNVPITNYGMAFAHAQGILERTTRMFEP
>NC_019954.2|WP_013777358.1|233157_234207_+|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE
MNIYQLVDSICAGYVPSVDEVELLLNADEPETSYIFSMADNITERYCSNKIHIRGIIEFSSYCRCNCAYCGLNAGNHKLSRYRMQPQEIIDTAAKAYEAGYKTLVLQSGEDLWYTREKISWIIKGIKSIGDIAITLSIGEREYEDYKQWKKDGADRFLLKHETINQSLYNKLHTHSNIESRIKCLLQLKELGYQVGDGFMIGLPGQTLRDIAEDILFLNELDVDMAGIGPFIPHKDTILKDAKAGSNMITLKAVAVTRLILKKVHLPATTALWTLDNQDGKKALKAGANVVMLKLEPYKYRRLYEIYPKDFDAKSNIKQERLKIEELILSMGKQVAEDRGDSIKLIERQ
>NC_019954.2|WP_013777357.1|232643_233033_+|30S-ribosomal-protein-S9
MKQAVLATGRRKTAVAKVWIMPGSGKITINKRPIDDYFGFETLKAEVKRPLEKINGLDKFDVIASVKGGGYTGQAGAIRHGIARALLKIDGDFRPILKKEGYLTRDPRMTERKKYGLKKARRAPQFSKR
>NC_019954.2|WP_013777356.1|232189_232624_+|50S-ribosomal-protein-L13
MSTFMAKKEEVKRDWYVIDAAGKPLGRLATQVAMILKGKHKPIYTPHVDTGDYVIIVNADKVILTGKKMDNKMYYSHTGYPGGIKSQNFRSLMSKSPEKVVYKAVWGMLPHNALGRKMIKKLKIYAGAEHPHEAQKPQSLTVKI
>NC_019954.2|WP_013777355.1|231394_232126_+|tRNA-pseudouridine(38-40)-synthase-TruA
MNVKILLEYEGTAYSGWQRQKNAISIQEVLENAIKSITGEAVNVIGSGRTDAGVHALGQVANFKTQTKIPIEKLPYAINSKLPEDIVVKHAEIVPEDFHARFWAKAKIYTYTIYNAKFPSPLLKRYSYFYPRPLNVRAMKKAADMLIGTHDFASFMASNSPVKSTVRCIERLEVFQNGDIVKFEIEANGFLYNMVRIIAGTLLDVGINKKKANDIISIIKSKDRSMAGKTLPPQGLCLIKVIY
>NC_019954.2|WP_013777354.1|230586_231381_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MREITIGQYIPGDSIVHRLDPRTKIIITLAYMILLFMLNNFYGYIFPVGFIILATLLSGISVRYLLKGLKPLIFIIILTFLLNSFMTKGRVIYQLGPLDITYEGLSQGAFMAIRLILLIIGTSLLTLTTSPISLTDGIEVLLSPFKKIGMPAHELAMMMTIALRFIPTLLEETDKIMKAQMARGADFESGNLINRAKNLVPLLVPLFISAFRRADDLAMAMEARCYHGGENRTRMKELKMTFLDIATFIVFILIAGGGIASRFV
>NC_019954.2|WP_013777352.1|228910_229747_+|energy-coupling-factor-transporter-ATPase
MKIAAEIVALDVYYQYAASSDLALKNINLRIEPGEFVAIIGPNGSGKSTLAKLFNGLYTPSEGDIFVAGFNTKNQDDIWKIRQKAGMVFQNPDNQIVATIVEEDVAFGPENLGIPPEEIRHRVKEALEIVELTEYADKAPHLLSGGQKQRVAIAGILAMKPDCIILDEPTAMLDPVGRKEVISTVKKLNRNEGKTIVLITHFMEEAVQADRVLVMEKGKVVMEGKPNEIFSQVERLKKLGLDVPQVTELAYKLTKDNVPVRRDILTVEEMVDCLCQLM
>NC_019954.2|WP_013777351.1|228532_228865_+|50S-ribosomal-protein-L17
MRKLGRPSGHRKMMLRNLTTDLLKYGRIETTETRAKEVRRMAEKMITLAKKDDLAARRLVLAEVLDETTVKNLFDNIAPKYKDQNGGYVRITKVGPRQGDAAPKAILELV
>NC_019954.2|WP_013777350.1|227569_228517_+|DNA-directed-RNA-polymerase-subunit-alpha
MMDIEKPRIELIEASADNTFGRIVVEPLERGYGTTLGNSMRRVLLSSLPGAAVTSIKIDGVQHEFSTIPGVTEDTTEIIMNIKALAIMMHSDEPKLLRIEAQDEGEVKAKDIIADADVEIMNPELHIATLEKDAKLFMELTLEKGKGYVTADKNKKPNHPIGVIAIDSIFTPVHKVNFNVEHTRVGQRTDYDRLIMEIWTNGTIKPDDAVSAAAKILMDHFSLFAGLTEKPQVEDAPVEEEKDDREKILEMPIEELDLSVRSYNCLKRAGINTIYELTQKTAEDMMKVRNLGKKSLEEVETKLSTFNLSLKQPED
>NC_019954.2|WP_013777361.1|242182_243094_+|DMT-family-transporter
MSSEKRMYISLFSVACFWGTSWSVSKIGLRELSPVHLAVLRFILASIIFFCIVKLFYRDYVIEREDRKWLWILGFLGVVLYFFIQYYGLDMTTTVNSSILIATSPIFTIFLSAKLFHQEKLNYSDLLGILIAFVGVFLVFTAGKGISIGRSTIYGDLLLLLNSLVWALFTVLGKNLVDKYDPFVVMAYINIYATITVLPIAFTPAFINSVKAASITTWAAALYLAVFCSVYSYYMWYKGIKTIGASKTAVFNYVNPMVAVIIGIILLKEDWNIYTIIGGILVFIGVYAASARKGDERIETVDS
>NC_019954.2|WP_013777362.1|243200_243881_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MEKIREGKTKTVFDTGDGNILLKFRDDVTGTGDVVDPGANTVIGKIEGKGNASLKLSKHFFELLKRDGIRTHYIDADLKENTMLVKRADTFGDGLEFICRLKAAGSFVRRYGRYVEEDQPLDYLVEITLKDDDRGDPLINEEALVQLKLMTKEEVSEAIALTKKITKIVKQECERFDLELIDIKFEFARVEGEIAVIDEISGDNMRVRKNGQAVMQKELCDIICGK
>NC_019954.2|WP_013777363.1|244073_244985_-|thioredoxin-disulfide-reductase
MYDVTIVGAGPAGLSAGLYAARAKLSTVIIEKMYPGGQAAITYRIENYPGFSDGIGGIELTDAMKSQAEKFDAKFLNGCVEKIEKQDGVFRVFMNGESITAKTVILASGAQPKKIGVKGEQEFTGKGVSYCATCDGAFYFDRTVAVVGGGDTAIEEALFLTRFASKIYVIHRRDQLRATKILQERAFQNDKISFVWDSVVNEIRGEDAVKEVIVKNVKTGSLNSIPIDGIFVAIGQSPATNFVKNLVVLDEQGYIITNDKMMTDVRGIFAAGDVRQKPLRQVITAAADGAIAAVEAGRFIEGQ
>NC_019954.2|WP_013777365.1|246207_247428_-|patatin-like-phospholipase-family-protein
MFGLVLEGGGAKGAYQIGAWKALRELGVDIKGVAGTSVGALNGAMIVQGDFEKTYDTWYNISFDKILNIDDSEIAAIKNRELFPENFFHVVRTIRELFFEHGLDITPLRQLLNCNICEDKVRHSGKDFGIVTVALTDLKPVELYIEDIPEGKLVDYLMASANLPIFKMDKIDGKLFIDGGFFDNFPIKLLMAKGYKDIIGIRLYGIGRTRRINKDKLNLITIEPSEDLGGTLDFSSERARRNLNLGYYDTLSVINKYSGRFYYIIANHPEDYYANIFFNLSRQTVLKLANIMGLPEKMPYRRLLFEKIIPRLSEILGLGSKASYKDIFIGILEKAAVLDGIEKFKIYDFDEFLYTVISKHQKTSEHISDKIPRLLKKSDLVLKTVKEQLSPEIIDVFIDELKIRFN
>NC_019954.2|WP_013777366.1|247879_248356_+|transcription-elongation-factor-GreA
MAKKEVVLTQEGLKKMEEELEYLKSVKRREIAARIKQAIDFGDISENSEYDEAKNEQAFVEGRIALLEEKLRNAKLIDEVDISTDVVSVGSKVKLKDLDTGDIFEYMIVGSAEANPIENKISNESPVGNALIGEKKGSIVEVSVPAGIIKYEIMDIMK
>NC_019954.2|WP_013777367.1|248373_249855_+|lysine--tRNA-ligase
MDYLNDQSEINEIQKVRLQKLQELKDMGVNPFGDKYPYSHNCQQIKANFDELENQNVKIAGRIMAIRGHGKAAFFDIQDNTGKIQVYIRKDNVSDDTFNLYKLLDIGDIVGIEGNVFKSKRGEISVSVNNMTILAKSLRPLPEKWHGLKDTDIRYRQRYLDLIVNPEVKQTFLTRSKIISAMRQFLDDKGFVEVETPVLSPIAGGAAARPFVTYHNALDMQLYLRIATELYLKRLIVGGFEKVYELGKDFRNEGISIKHNPEFTMVELYQAYADYKDMMKLAEDMIAYIAEKVLGTTKITYQGEEIDLTPPWTRMTMVEAVKHFTGIDFDSIASDEEARKVARELHIEEIKDCDTKGKVLNLIFEEKVEQNLVQPTFIYDYPIEISPLAKKKEDNPDLTYRFEAFVTGREIANAFSELNDPIDQRERFLQQLKEREAGDEEAHAFDEDYINALEYGMPPTGGMGIGVDRLVMLLTDSYSIRDVILFPTMRPKQ
>NC_019954.2|WP_013777368.1|255397_255865_+|MarR-family-transcriptional-regulator
MTNDNDRKLAESLDTLLRSITRWMKYIHRQQLVKADNLDITQKQYRVLCILEKNGPYKMSDLGEIVHTSYGSLTVMIDRLVDKNLVERCFLPEDRRVVMVKITPAGSQILKQYREDFLDLIEKNLERLNSEEKKRLQAAIDDIKSIVEENCNFLL
>NC_019954.2|WP_013777369.1|255984_256443_+|NUDIX-hydrolase
MLTRICSGGVVFFKDKVLILKNEKGEWVLPKGVIRPGRLAQEVAIERVKLEAGVNARIVSCVGETCYEFYSVTRQRPVCNQITWFLMEALSENCNPNVELNFSDGGFYPIEEALDMITYSQDKSLVRTSYKRYLEYCKEKEKNEDEKDEVIV
>NC_019954.2|WP_013777370.1|256466_256655_-|hypothetical-protein
MVEIDILAELSDMKIIDYRNTLTIVSLIEVLTEKGIICSNDVALKAQTLDAISEEQIKIHTI
>NC_019954.2|WP_041591468.1|256739_257744_-|AIR-synthase-family-protein
MKAGKVPPELLKSSVYPYVGKLRKEVLVHSGFGEDCSIIDFGDSVAVLSTDPITGADIHSSHLAVYVSCNDVAACGAEPIGILVTLLLPIGSNESLLKELMKEINEAANKVGIEILGGHSEITSAVSKSIISTTAIGITGKDKFVTSSGAKPGDAIIVTKTLGLEGSAILASDFEEFLIKKLPRETIEKAKNFIEKISVVDDGIIASKVGVSAMHDITEGGLLGACYEVAEASGVGVEIYQDLLPILPETQDICKAFGINPLGLISSGSMFICTPFADEVIAALNESKIDAAVIGKVTSQEQGKFIVSSGKKCPIVPFERDELYNAIEKVHNQL

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Crispr_ID: NC_019954_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019954_6

240442-241551

Orphan

Consensus_repeat	Method
GTTTATAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTATAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder
GTTTATAGCCTACCTATAAGGAATTGAAAC	CRT

16 spacers

The CRISPR arrays of NC_019954_6

>merge|NC_019954|6|240442-241551|PILER-CR,CRISPRCasFinder,CRT
GTTTATAGCCTACCTATAAGGAATTGAAACTTATAAATGGGGTGAAATTATGGATCTTACGACAATTAGTTTATAGCCTACCTATAAGGAATTGAAACCCAGCCTTGGCACCAGCTCTATTGGTATATATCCGGGTTTATAGCCTACCTATAAGGAATTGAAACTGAATTGTCCTTGGATGACATCCCGCCATATTTGCCGTTTATAGCCTACCTATAAGGAATTGAAACCCAGCCTTGGCACCAGCTCTATTGGTATATATCCGGCGTTTATAGCCTACCTATAAGGAATTGAAACATAATCTCATATTCTTTTTTCATAGTCTTCGTTCACCGTTTATAGCCTACCTATAAGGAATTGAAACACGACTATCCCGGGAGAACACCCGAGACTGCCCAATTTTGTTTATAGCCTACCTATAAGGAATTGAAACACCAGAGCAGGCGCGAAACCCGTAGTTGCTGTTGGCATTGCCGTTTATAGCCTACCTATAAGGAATTGAAACTCGGCTGTCCTGGCTCGGGAATGAATTGAGAAGTGACGTTTATAGCCTACCTATAAGGAATTGAAACTATGCCTACAAAGTCTTTTTATCAAGTGCTATCCGCAGTTTATAGCCTACCTATAAGGAATTGAAACTCAAAAGAGGAGAGAATATCAAGAACTGGCAAGGGATTCGTTTATAGCCTACCTATAAGGAATTGAAACTCTACTTTGTCCCAGTCAATACATGCCCATATTTCATAGTTTATAGCCTACCTATAAGGAATTGAAACATAAACTTGTCAACCGATTCGCTAATAATACCTTCCACGTTTATAGCCTACCTATAAGGAATTGAAACGGCTCTAATGCCCTAAATTGGTCTAACCCGTTCTTTGTTTATAGCCTACCTATAAGGGATTGAAACTCACAATCTTTTTTTGCGCAATCACTCTTGTCTGGGTTTATAGCCTACCTATAAGGGATTGAAACGCCCTTGAATTCACTTTTGATAATGAATATATCAAAGAAGTTTATAGCCTACCTATAAGGGATTGAAACGCTTTTCTTCTTTTGTCTTTATCTTTCTCTATCCCAGCTTATAACCTACCTATAAGGGACTTGAAA

>NC_019954|6|5|240442-241485|PILER-CR
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTATAAATGGGGTGAAATTATGGATCTTACGACAATTA
GTTTATAGCCTACCTATAAGGAATTGAAAC	CCAGCCTTGGCACCAGCTCTATTGGTATATATCCGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGAATTGTCCTTGGATGACATCCCGCCATATTTGCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CCAGCCTTGGCACCAGCTCTATTGGTATATATCCGGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAATCTCATATTCTTTTTTCATAGTCTTCGTTCACC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACGACTATCCCGGGAGAACACCCGAGACTGCCCAATTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACCAGAGCAGGCGCGAAACCCGTAGTTGCTGTTGGCATTGCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCGGCTGTCCTGGCTCGGGAATGAATTGAGAAGTGAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATGCCTACAAAGTCTTTTTATCAAGTGCTATCCGCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCAAAAGAGGAGAGAATATCAAGAACTGGCAAGGGATTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTACTTTGTCCCAGTCAATACATGCCCATATTTCATA
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAAACTTGTCAACCGATTCGCTAATAATACCTTCCAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	GGCTCTAATGCCCTAAATTGGTCTAACCCGTTCTTT
GTTTATAGCCTACCTATAAGGGATTGAAAC	TCACAATCTTTTTTTGCGCAATCACTCTTGTCTGG
GTTTATAGCCTACCTATAAGGGATTGAAAC	GCCCTTGAATTCACTTTTGATAATGAATATATCAAAGAA
GTTTATAGCCTACCTATAAGGGATTGAAAC

>NC_019954|6|6|240442-241551|CRISPRCasFinder
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTATAAATGGGGTGAAATTATGGATCTTACGACAATTA
GTTTATAGCCTACCTATAAGGAATTGAAAC	CCAGCCTTGGCACCAGCTCTATTGGTATATATCCGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGAATTGTCCTTGGATGACATCCCGCCATATTTGCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CCAGCCTTGGCACCAGCTCTATTGGTATATATCCGGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAATCTCATATTCTTTTTTCATAGTCTTCGTTCACC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACGACTATCCCGGGAGAACACCCGAGACTGCCCAATTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACCAGAGCAGGCGCGAAACCCGTAGTTGCTGTTGGCATTGCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCGGCTGTCCTGGCTCGGGAATGAATTGAGAAGTGAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATGCCTACAAAGTCTTTTTATCAAGTGCTATCCGCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCAAAAGAGGAGAGAATATCAAGAACTGGCAAGGGATTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTACTTTGTCCCAGTCAATACATGCCCATATTTCATA
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAAACTTGTCAACCGATTCGCTAATAATACCTTCCAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	GGCTCTAATGCCCTAAATTGGTCTAACCCGTTCTTT
GTTTATAGCCTACCTATAAGGGATTGAAAC	TCACAATCTTTTTTTGCGCAATCACTCTTGTCTGG
GTTTATAGCCTACCTATAAGGGATTGAAAC	GCCCTTGAATTCACTTTTGATAATGAATATATCAAAGAA
GTTTATAGCCTACCTATAAGGGATTGAAAC	GCTTTTCTTCTTTTGTCTTTATCTTTCTCTATCCCA
GCTTATAACCTACCTATAAGGGACTTGAAA

>NC_019954|6|5|240442-241551|CRT
GTTTATAGCCTACCTATAAGGAATTGAAAC	TTATAAATGGGGTGAAATTATGGATCTTACGACAATTA
GTTTATAGCCTACCTATAAGGAATTGAAAC	CCAGCCTTGGCACCAGCTCTATTGGTATATATCCGG
GTTTATAGCCTACCTATAAGGAATTGAAAC	TGAATTGTCCTTGGATGACATCCCGCCATATTTGCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	CCAGCCTTGGCACCAGCTCTATTGGTATATATCCGGC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAATCTCATATTCTTTTTTCATAGTCTTCGTTCACC
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACGACTATCCCGGGAGAACACCCGAGACTGCCCAATTTT
GTTTATAGCCTACCTATAAGGAATTGAAAC	ACCAGAGCAGGCGCGAAACCCGTAGTTGCTGTTGGCATTGCC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCGGCTGTCCTGGCTCGGGAATGAATTGAGAAGTGAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TATGCCTACAAAGTCTTTTTATCAAGTGCTATCCGCA
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCAAAAGAGGAGAGAATATCAAGAACTGGCAAGGGATTC
GTTTATAGCCTACCTATAAGGAATTGAAAC	TCTACTTTGTCCCAGTCAATACATGCCCATATTTCATA
GTTTATAGCCTACCTATAAGGAATTGAAAC	ATAAACTTGTCAACCGATTCGCTAATAATACCTTCCAC
GTTTATAGCCTACCTATAAGGAATTGAAAC	GGCTCTAATGCCCTAAATTGGTCTAACCCGTTCTTT
GTTTATAGCCTACCTATAAGGGATTGAAAC	TCACAATCTTTTTTTGCGCAATCACTCTTGTCTGG
GTTTATAGCCTACCTATAAGGGATTGAAAC	GCCCTTGAATTCACTTTTGATAATGAATATATCAAAGAA
GTTTATAGCCTACCTATAAGGGATTGAAAC	GCTTTTCTTCTTTTGTCTTTATCTTTCTCTATCCCA
GCTTATAACCTACCTATAAGGGACTTGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019954.2\|WP_013777370.1\|256466_256655_-\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013777367.1\|248373_249855_+\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NC_019954.2\|WP_023211328.1\|235404_236751_-\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240543
NC_019954.2\|WP_013777362.1\|243200_243881_+\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl\|CDD\|133470
NC_019954.2\|WP_013777361.1\|242182_243094_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NC_019954.2\|WP_041591468.1\|256739_257744_-\|AIR-synthase-family-protein	unknown	unknown	gnl\|CDD\|100037
NC_019954.2\|WP_013777366.1\|247879_248356_+\|transcription-elongation-factor-GreA	unknown	unknown	gnl\|CDD\|234693
NC_019954.2\|WP_013777357.1\|232643_233033_+\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
NC_019954.2\|WP_013777356.1\|232189_232624_+\|50S-ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
NC_019954.2\|WP_013777354.1\|230586_231381_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NC_019954.2\|WP_013777355.1\|231394_232126_+\|tRNA-pseudouridine(38-40)-synthase-TruA	unknown	unknown	gnl\|CDD\|234577
NC_019954.2\|WP_013777369.1\|255984_256443_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239645
NC_019954.2\|WP_013777352.1\|228910_229747_+\|energy-coupling-factor-transporter-ATPase	unknown	unknown	gnl\|CDD\|275313
NC_019954.2\|WP_013777363.1\|244073_244985_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NC_019954.2\|WP_013777358.1\|233157_234207_+\|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE	unknown	unknown	gnl\|CDD\|180835
NC_019954.2\|WP_013777365.1\|246207_247428_-\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|132848
NC_019954.2\|WP_013777368.1\|255397_255865_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_019954.2\|WP_013777359.1\|234214_235408_+\|[FeFe]-hydrogenase-H-cluster-maturation-GTPase-HydF	unknown	unknown	gnl\|CDD\|274853
NC_019954.2\|WP_013777350.1\|227569_228517_+\|DNA-directed-RNA-polymerase-subunit-alpha	unknown	unknown	gnl\|CDD\|235359
NC_019954.2\|WP_013777351.1\|228532_228865_+\|50S-ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522

Protein	Function_ID	Function_description	E-value
NC_019954.2\|WP_013777367.1\|248373_249855_+\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NC_019954.2\|WP_023211328.1\|235404_236751_-\|MATE-family-efflux-transporter	gnl\|CDD\|240543	cd13138, MATE_yoeA_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	3.64499e-122
NC_019954.2\|WP_013777362.1\|243200_243881_+\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl\|CDD\|133470	cd01415, SAICAR_synt_PurC, bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase. A subfamily of SAICAR synthetases represented by the Thermotoga maritima (Tm) enzyme and E. coli PurC. SAICAR synthetase catalyzes the seventh step of the de novo biosynthesis of purine nucleotides (also reported as eighth step). It converts 5-aminoimidazole-4-carboxyribonucleotide (CAIR), ATP, and L-aspartate into 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR), ADP, and phosphate.	5.27122e-52
NC_019954.2\|WP_013777361.1\|242182_243094_+\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.55481e-25
NC_019954.2\|WP_041591468.1\|256739_257744_-\|AIR-synthase-family-protein	gnl\|CDD\|100037	cd06061, PurM-like1, AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two conserved domains and seem to dimerize. The N-terminal domain forms the dimer interface and is a putative ATP binding domain.	2.62122e-129
NC_019954.2\|WP_013777366.1\|247879_248356_+\|transcription-elongation-factor-GreA	gnl\|CDD\|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	3.33479e-69
NC_019954.2\|WP_013777357.1\|232643_233033_+\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	3.12559e-77
NC_019954.2\|WP_013777356.1\|232189_232624_+\|50S-ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.50804e-99
NC_019954.2\|WP_013777354.1\|230586_231381_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.06455e-48
NC_019954.2\|WP_013777355.1\|231394_232126_+\|tRNA-pseudouridine(38-40)-synthase-TruA	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	6.07375e-139
NC_019954.2\|WP_013777369.1\|255984_256443_+\|NUDIX-hydrolase	gnl\|CDD\|239645	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most preferred substrate, hydrolyzes to produce two ATP molecules, which is a novel hydrolysis mode for Ap6A. These results indicate that Ap6A hydrolase is a diadenosine polyphosphate hydrolase. It requires the presence of a divalent cation, such as Mn2+, Mg2+, Zn2+, and Co2+, for activity. Members of the Nudix superfamily are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site.	2.6638e-38
NC_019954.2\|WP_013777352.1\|228910_229747_+\|energy-coupling-factor-transporter-ATPase	gnl\|CDD\|275313	TIGR04520, ECF_ATPase_1, energy-coupling factor transporter ATPase. Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate].	3.85581e-178
NC_019954.2\|WP_013777363.1\|244073_244985_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	9.24389e-145
NC_019954.2\|WP_013777358.1\|233157_234207_+\|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE	gnl\|CDD\|180835	PRK07094, PRK07094, biotin synthase; Provisional.	7.1476e-171
NC_019954.2\|WP_013777365.1\|246207_247428_-\|patatin-like-phospholipase-family-protein	gnl\|CDD\|132848	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli. Patatin-like phospholipase similar to Z1214 protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	3.15524e-63
NC_019954.2\|WP_013777368.1\|255397_255865_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.32054e-19
NC_019954.2\|WP_013777359.1\|234214_235408_+\|[FeFe]-hydrogenase-H-cluster-maturation-GTPase-HydF	gnl\|CDD\|274853	TIGR03918, hydrogenase_maturation_GTPase_HydF, [FeFe] hydrogenase H-cluster maturation GTPase HydF. This model describes the family of the [Fe] hydrogenase maturation protein HypF as characterized in Chlamydomonas reinhardtii and found, in an operon with radical SAM proteins HydE and HydG, in numerous bacteria. It has GTPase activity, can bind an 4Fe-4S cluster, and is essential for hydrogenase activity. [Protein fate, Protein modification and repair].	0
NC_019954.2\|WP_013777350.1\|227569_228517_+\|DNA-directed-RNA-polymerase-subunit-alpha	gnl\|CDD\|235359	PRK05182, PRK05182, DNA-directed RNA polymerase subunit alpha; Provisional.	0
NC_019954.2\|WP_013777351.1\|228532_228865_+\|50S-ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	1.59899e-60

>NC_019954.2|WP_023211328.1|235404_236751_-|MATE-family-efflux-transporter
MTVGTPWKRIVEFSIPMLVGNIAQQLYNTVDSIVIGRYVGDNALAAVGSALPIFNFLLVFFVAVSTGAGIMVSQYFGAKDREKLSRSIGACITLTAIVATIIMIIGPIVVRPMLVLINTPESIIDWCASYLLILLVGNWGFSYFNILSGILRGLGDSLSALMFLLISTVLNIFLDIWFVAGLNMGVPGVALATVIAQVISAVLCAMKLKTMDYVFDLNLNMLKPKKEYVVQLLKLGLPSGLTQVIFSLAMITVQSLTNTFGEMIIACNVIVMRVDGFAMMPNFTFGVAMTTFAGQNVGAKKMDRVEEGTRQGLAIAVGVSIVITIIILIFGRYLMDIFTDTAELVDLSMKMMRILAVGYVAMAVTQVLSGVMRGAGDTMTPMWISLITTIFLRVPIAYGIAYLTRSAQYPNGRPESVFVSLLIAWVSGAVITSIFYKKGNWREKVLLS
>NC_019954.2|WP_013777359.1|234214_235408_+|[FeFe]-hydrogenase-H-cluster-maturation-GTPase-HydF
MNDTPRANRLHIGLFGRRNSGKSSLINAITGQEIALVSDFPGTTTDPVYKAMELLPIGPVVFIDTAGLDDVGDLGELRIKKTLEVMDKTDIALVVFSTENLDFSLEKRWCQELRSRNIPIIGVVNKIDKRDVDIKDLTKEFDFPFIKVSANKRENIGKLKEMIHQNAPMDFELSTLVGDIITPKSLVVLVTPQDIQAPKNRLILPQVQTIRDILDNNCMALVAKETELLDLLNCLNKKPALVITDSQVFHIVSKIVPEDIPLTSFSIIMSRYKGELSTLVRGAKAMDELKPNDRVLIEEACTHHPLENDIGRQKLPALLENKAGGKLQIEIKVGGDFPEDLTPYALILHCGACMLNRKQMLTRIIRAREQNVPITNYGMAFAHAQGILERTTRMFEP
>NC_019954.2|WP_013777358.1|233157_234207_+|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE
MNIYQLVDSICAGYVPSVDEVELLLNADEPETSYIFSMADNITERYCSNKIHIRGIIEFSSYCRCNCAYCGLNAGNHKLSRYRMQPQEIIDTAAKAYEAGYKTLVLQSGEDLWYTREKISWIIKGIKSIGDIAITLSIGEREYEDYKQWKKDGADRFLLKHETINQSLYNKLHTHSNIESRIKCLLQLKELGYQVGDGFMIGLPGQTLRDIAEDILFLNELDVDMAGIGPFIPHKDTILKDAKAGSNMITLKAVAVTRLILKKVHLPATTALWTLDNQDGKKALKAGANVVMLKLEPYKYRRLYEIYPKDFDAKSNIKQERLKIEELILSMGKQVAEDRGDSIKLIERQ
>NC_019954.2|WP_013777357.1|232643_233033_+|30S-ribosomal-protein-S9
MKQAVLATGRRKTAVAKVWIMPGSGKITINKRPIDDYFGFETLKAEVKRPLEKINGLDKFDVIASVKGGGYTGQAGAIRHGIARALLKIDGDFRPILKKEGYLTRDPRMTERKKYGLKKARRAPQFSKR
>NC_019954.2|WP_013777356.1|232189_232624_+|50S-ribosomal-protein-L13
MSTFMAKKEEVKRDWYVIDAAGKPLGRLATQVAMILKGKHKPIYTPHVDTGDYVIIVNADKVILTGKKMDNKMYYSHTGYPGGIKSQNFRSLMSKSPEKVVYKAVWGMLPHNALGRKMIKKLKIYAGAEHPHEAQKPQSLTVKI
>NC_019954.2|WP_013777355.1|231394_232126_+|tRNA-pseudouridine(38-40)-synthase-TruA
MNVKILLEYEGTAYSGWQRQKNAISIQEVLENAIKSITGEAVNVIGSGRTDAGVHALGQVANFKTQTKIPIEKLPYAINSKLPEDIVVKHAEIVPEDFHARFWAKAKIYTYTIYNAKFPSPLLKRYSYFYPRPLNVRAMKKAADMLIGTHDFASFMASNSPVKSTVRCIERLEVFQNGDIVKFEIEANGFLYNMVRIIAGTLLDVGINKKKANDIISIIKSKDRSMAGKTLPPQGLCLIKVIY
>NC_019954.2|WP_013777354.1|230586_231381_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MREITIGQYIPGDSIVHRLDPRTKIIITLAYMILLFMLNNFYGYIFPVGFIILATLLSGISVRYLLKGLKPLIFIIILTFLLNSFMTKGRVIYQLGPLDITYEGLSQGAFMAIRLILLIIGTSLLTLTTSPISLTDGIEVLLSPFKKIGMPAHELAMMMTIALRFIPTLLEETDKIMKAQMARGADFESGNLINRAKNLVPLLVPLFISAFRRADDLAMAMEARCYHGGENRTRMKELKMTFLDIATFIVFILIAGGGIASRFV
>NC_019954.2|WP_013777352.1|228910_229747_+|energy-coupling-factor-transporter-ATPase
MKIAAEIVALDVYYQYAASSDLALKNINLRIEPGEFVAIIGPNGSGKSTLAKLFNGLYTPSEGDIFVAGFNTKNQDDIWKIRQKAGMVFQNPDNQIVATIVEEDVAFGPENLGIPPEEIRHRVKEALEIVELTEYADKAPHLLSGGQKQRVAIAGILAMKPDCIILDEPTAMLDPVGRKEVISTVKKLNRNEGKTIVLITHFMEEAVQADRVLVMEKGKVVMEGKPNEIFSQVERLKKLGLDVPQVTELAYKLTKDNVPVRRDILTVEEMVDCLCQLM
>NC_019954.2|WP_013777351.1|228532_228865_+|50S-ribosomal-protein-L17
MRKLGRPSGHRKMMLRNLTTDLLKYGRIETTETRAKEVRRMAEKMITLAKKDDLAARRLVLAEVLDETTVKNLFDNIAPKYKDQNGGYVRITKVGPRQGDAAPKAILELV
>NC_019954.2|WP_013777350.1|227569_228517_+|DNA-directed-RNA-polymerase-subunit-alpha
MMDIEKPRIELIEASADNTFGRIVVEPLERGYGTTLGNSMRRVLLSSLPGAAVTSIKIDGVQHEFSTIPGVTEDTTEIIMNIKALAIMMHSDEPKLLRIEAQDEGEVKAKDIIADADVEIMNPELHIATLEKDAKLFMELTLEKGKGYVTADKNKKPNHPIGVIAIDSIFTPVHKVNFNVEHTRVGQRTDYDRLIMEIWTNGTIKPDDAVSAAAKILMDHFSLFAGLTEKPQVEDAPVEEEKDDREKILEMPIEELDLSVRSYNCLKRAGINTIYELTQKTAEDMMKVRNLGKKSLEEVETKLSTFNLSLKQPED
>NC_019954.2|WP_013777361.1|242182_243094_+|DMT-family-transporter
MSSEKRMYISLFSVACFWGTSWSVSKIGLRELSPVHLAVLRFILASIIFFCIVKLFYRDYVIEREDRKWLWILGFLGVVLYFFIQYYGLDMTTTVNSSILIATSPIFTIFLSAKLFHQEKLNYSDLLGILIAFVGVFLVFTAGKGISIGRSTIYGDLLLLLNSLVWALFTVLGKNLVDKYDPFVVMAYINIYATITVLPIAFTPAFINSVKAASITTWAAALYLAVFCSVYSYYMWYKGIKTIGASKTAVFNYVNPMVAVIIGIILLKEDWNIYTIIGGILVFIGVYAASARKGDERIETVDS
>NC_019954.2|WP_013777362.1|243200_243881_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MEKIREGKTKTVFDTGDGNILLKFRDDVTGTGDVVDPGANTVIGKIEGKGNASLKLSKHFFELLKRDGIRTHYIDADLKENTMLVKRADTFGDGLEFICRLKAAGSFVRRYGRYVEEDQPLDYLVEITLKDDDRGDPLINEEALVQLKLMTKEEVSEAIALTKKITKIVKQECERFDLELIDIKFEFARVEGEIAVIDEISGDNMRVRKNGQAVMQKELCDIICGK
>NC_019954.2|WP_013777363.1|244073_244985_-|thioredoxin-disulfide-reductase
MYDVTIVGAGPAGLSAGLYAARAKLSTVIIEKMYPGGQAAITYRIENYPGFSDGIGGIELTDAMKSQAEKFDAKFLNGCVEKIEKQDGVFRVFMNGESITAKTVILASGAQPKKIGVKGEQEFTGKGVSYCATCDGAFYFDRTVAVVGGGDTAIEEALFLTRFASKIYVIHRRDQLRATKILQERAFQNDKISFVWDSVVNEIRGEDAVKEVIVKNVKTGSLNSIPIDGIFVAIGQSPATNFVKNLVVLDEQGYIITNDKMMTDVRGIFAAGDVRQKPLRQVITAAADGAIAAVEAGRFIEGQ
>NC_019954.2|WP_013777365.1|246207_247428_-|patatin-like-phospholipase-family-protein
MFGLVLEGGGAKGAYQIGAWKALRELGVDIKGVAGTSVGALNGAMIVQGDFEKTYDTWYNISFDKILNIDDSEIAAIKNRELFPENFFHVVRTIRELFFEHGLDITPLRQLLNCNICEDKVRHSGKDFGIVTVALTDLKPVELYIEDIPEGKLVDYLMASANLPIFKMDKIDGKLFIDGGFFDNFPIKLLMAKGYKDIIGIRLYGIGRTRRINKDKLNLITIEPSEDLGGTLDFSSERARRNLNLGYYDTLSVINKYSGRFYYIIANHPEDYYANIFFNLSRQTVLKLANIMGLPEKMPYRRLLFEKIIPRLSEILGLGSKASYKDIFIGILEKAAVLDGIEKFKIYDFDEFLYTVISKHQKTSEHISDKIPRLLKKSDLVLKTVKEQLSPEIIDVFIDELKIRFN
>NC_019954.2|WP_013777366.1|247879_248356_+|transcription-elongation-factor-GreA
MAKKEVVLTQEGLKKMEEELEYLKSVKRREIAARIKQAIDFGDISENSEYDEAKNEQAFVEGRIALLEEKLRNAKLIDEVDISTDVVSVGSKVKLKDLDTGDIFEYMIVGSAEANPIENKISNESPVGNALIGEKKGSIVEVSVPAGIIKYEIMDIMK
>NC_019954.2|WP_013777367.1|248373_249855_+|lysine--tRNA-ligase
MDYLNDQSEINEIQKVRLQKLQELKDMGVNPFGDKYPYSHNCQQIKANFDELENQNVKIAGRIMAIRGHGKAAFFDIQDNTGKIQVYIRKDNVSDDTFNLYKLLDIGDIVGIEGNVFKSKRGEISVSVNNMTILAKSLRPLPEKWHGLKDTDIRYRQRYLDLIVNPEVKQTFLTRSKIISAMRQFLDDKGFVEVETPVLSPIAGGAAARPFVTYHNALDMQLYLRIATELYLKRLIVGGFEKVYELGKDFRNEGISIKHNPEFTMVELYQAYADYKDMMKLAEDMIAYIAEKVLGTTKITYQGEEIDLTPPWTRMTMVEAVKHFTGIDFDSIASDEEARKVARELHIEEIKDCDTKGKVLNLIFEEKVEQNLVQPTFIYDYPIEISPLAKKKEDNPDLTYRFEAFVTGREIANAFSELNDPIDQRERFLQQLKEREAGDEEAHAFDEDYINALEYGMPPTGGMGIGVDRLVMLLTDSYSIRDVILFPTMRPKQ
>NC_019954.2|WP_013777368.1|255397_255865_+|MarR-family-transcriptional-regulator
MTNDNDRKLAESLDTLLRSITRWMKYIHRQQLVKADNLDITQKQYRVLCILEKNGPYKMSDLGEIVHTSYGSLTVMIDRLVDKNLVERCFLPEDRRVVMVKITPAGSQILKQYREDFLDLIEKNLERLNSEEKKRLQAAIDDIKSIVEENCNFLL
>NC_019954.2|WP_013777369.1|255984_256443_+|NUDIX-hydrolase
MLTRICSGGVVFFKDKVLILKNEKGEWVLPKGVIRPGRLAQEVAIERVKLEAGVNARIVSCVGETCYEFYSVTRQRPVCNQITWFLMEALSENCNPNVELNFSDGGFYPIEEALDMITYSQDKSLVRTSYKRYLEYCKEKEKNEDEKDEVIV
>NC_019954.2|WP_013777370.1|256466_256655_-|hypothetical-protein
MVEIDILAELSDMKIIDYRNTLTIVSLIEVLTEKGIICSNDVALKAQTLDAISEEQIKIHTI
>NC_019954.2|WP_041591468.1|256739_257744_-|AIR-synthase-family-protein
MKAGKVPPELLKSSVYPYVGKLRKEVLVHSGFGEDCSIIDFGDSVAVLSTDPITGADIHSSHLAVYVSCNDVAACGAEPIGILVTLLLPIGSNESLLKELMKEINEAANKVGIEILGGHSEITSAVSKSIISTTAIGITGKDKFVTSSGAKPGDAIIVTKTLGLEGSAILASDFEEFLIKKLPRETIEKAKNFIEKISVVDDGIIASKVGVSAMHDITEGGLLGACYEVAEASGVGVEIYQDLLPILPETQDICKAFGINPLGLISSGSMFICTPFADEVIAALNESKIDAAVIGKVTSQEQGKFIVSSGKKCPIVPFERDELYNAIEKVHNQL

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Crispr_ID: NC_019954_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019954_7

1375922-1376035

Orphan

Consensus_repeat	Method
TCTAAATCTGATAATTAATTGCTACAATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019954_7

>merge|NC_019954|7|1375922-1376035|CRISPRCasFinder
TCTAAATCTGATAATTAATTGCTACAATCACATAAAATACACATCCATCAATCAATTAAAATACACATCCATCAATCAATTCAATCTAAATCTGATAATTAATCGCTACAATCA

>NC_019954|7|7|1375922-1376035|CRISPRCasFinder
TCTAAATCTGATAATTAATTGCTACAATCA	CATAAAATACACATCCATCAATCAATTAAAATACACATCCATCAATCAATTCAA
TCTAAATCTGATAATTAATCGCTACAATCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019954.2\|WP_013778407.1\|1384364_1385414_-\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906
NC_019954.2\|WP_013778392.1\|1370737_1370995_+\|RNA-chaperone-Hfq	unknown	unknown	gnl\|CDD\|379947
NC_019954.2\|WP_013778399.1\|1377014_1378217_-\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|235596
NC_019954.2\|WP_013778391.1\|1369755_1370700_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NC_019954.2\|WP_013778409.1\|1387457_1387832_-\|S-adenosylmethionine-decarboxylase-proenzyme	unknown	unknown	gnl\|CDD\|235105
NC_019954.2\|WP_013778397.1\|1373681_1374992_+\|methionine-gamma-lyase-family-protein	unknown	unknown	gnl\|CDD\|311036
NC_019954.2\|WP_013778396.1\|1373435_1373663_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013778398.1\|1375000_1375609_-\|transcriptional-repressor-LexA	unknown	unknown	gnl\|CDD\|234688
NC_019954.2\|WP_013778402.1\|1379701_1380472_-\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NC_019954.2\|WP_144312823.1\|1372226_1372817_+\|50S-ribosome-binding-GTPase	unknown	unknown	gnl\|CDD\|206646
NC_019954.2\|WP_013778389.1\|1365287_1367897_+\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NC_019954.2\|WP_013778393.1\|1371200_1372208_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|163057
NC_019954.2\|WP_144312824.1\|1372809_1373406_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013778400.1\|1378334_1379441_-\|ATPase-AAA	unknown	unknown	gnl\|CDD\|235878
NC_019954.2\|WP_013778403.1\|1380483_1381698_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NC_019954.2\|WP_013778401.1\|1379510_1379678_-\|YpmA-family-protein	unknown	unknown	gnl\|CDD\|379458
NC_019954.2\|WP_144312798.1\|1386428_1387232_-\|protein-glutamate-O-methyltransferase-CheR	unknown	unknown	gnl\|CDD\|224271
NC_019954.2\|WP_013778405.1\|1382378_1383359_-\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906
NC_019954.2\|WP_013778406.1\|1383360_1384374_-\|M42-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349906
NC_019954.2\|WP_013778390.1\|1367909_1369751_+\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|234630

Protein	Function_ID	Function_description	E-value
NC_019954.2\|WP_013778407.1\|1384364_1385414_-\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	1.12164e-135
NC_019954.2\|WP_013778392.1\|1370737_1370995_+\|RNA-chaperone-Hfq	gnl\|CDD\|379947	pfam17209, Hfq, Hfq protein.	4.56172e-40
NC_019954.2\|WP_013778399.1\|1377014_1378217_-\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
NC_019954.2\|WP_013778391.1\|1369755_1370700_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	3.63991e-161
NC_019954.2\|WP_013778409.1\|1387457_1387832_-\|S-adenosylmethionine-decarboxylase-proenzyme	gnl\|CDD\|235105	PRK03124, PRK03124, S-adenosylmethionine decarboxylase proenzyme; Provisional.	5.87061e-88
NC_019954.2\|WP_013778397.1\|1373681_1374992_+\|methionine-gamma-lyase-family-protein	gnl\|CDD\|311036	pfam06838, Met_gamma_lyase, Methionine gamma-lyase. This is a putative pyridoxal 5'-phosphate-dependent methionine gamma-lyase enzyme involved in methionine catabolism.	0
NC_019954.2\|WP_013778398.1\|1375000_1375609_-\|transcriptional-repressor-LexA	gnl\|CDD\|234688	PRK00215, PRK00215, transcriptional repressor LexA.	1.72529e-105
NC_019954.2\|WP_013778402.1\|1379701_1380472_-\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	3.8408e-129
NC_019954.2\|WP_144312823.1\|1372226_1372817_+\|50S-ribosome-binding-GTPase	gnl\|CDD\|206646	cd00880, Era_like, E. coli Ras-like protein (Era)-like GTPase. The Era (E. coli Ras-like protein)-like family includes several distinct subfamilies (TrmE/ThdF, FeoB, YihA (EngB), Era, and EngA/YfgK) that generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs), to the exclusion of other GTPases. TrmE is ubiquitous in bacteria and is a widespread mitochondrial protein in eukaryotes, but is absent from archaea. The yeast member of TrmE family, MSS1, is involved in mitochondrial translation; bacterial members are often present in translation-related operons. FeoB represents an unusual adaptation of GTPases for high-affinity iron (II) transport. YihA (EngB) family of GTPases is typified by the E. coli YihA, which is an essential protein involved in cell division control. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain. EngA and its orthologs are composed of two GTPase domains and, since the sequences of the two domains are more similar to each other than to other GTPases, it is likely that an ancient gene duplication, rather than a fusion of evolutionarily distinct GTPases, gave rise to this family.	7.32377e-12
NC_019954.2\|WP_013778389.1\|1365287_1367897_+\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NC_019954.2\|WP_013778393.1\|1371200_1372208_+\|AAA-family-ATPase	gnl\|CDD\|163057	TIGR02881, Stage_V_sporulation_protein_K, stage V sporulation protein K. Members of this protein family are the stage V sporulation protein K (SpoVK), a close homolog of the Rubisco expression protein CbbX (TIGR02880) and a members of the ATPase family associated with various cellular activities (pfam00004). Members are strictly limited to bacterial endospore-forming species, but are not universal in this group and are missing from the Clostridium group. [Cellular processes, Sporulation and germination].	4.56585e-141
NC_019954.2\|WP_013778400.1\|1378334_1379441_-\|ATPase-AAA	gnl\|CDD\|235878	PRK06851, PRK06851, hypothetical protein; Provisional.	4.45056e-121
NC_019954.2\|WP_013778403.1\|1380483_1381698_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	1.05781e-19
NC_019954.2\|WP_013778401.1\|1379510_1379678_-\|YpmA-family-protein	gnl\|CDD\|379458	pfam14084, DUF4264, Protein of unknown function (DUF4264). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length.	1.26642e-17
NC_019954.2\|WP_144312798.1\|1386428_1387232_-\|protein-glutamate-O-methyltransferase-CheR	gnl\|CDD\|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	8.87259e-91
NC_019954.2\|WP_013778405.1\|1382378_1383359_-\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	1.73192e-139
NC_019954.2\|WP_013778406.1\|1383360_1384374_-\|M42-family-metallopeptidase	gnl\|CDD\|349906	cd05656, M42_Frv, M42 Peptidase, endoglucanases. Peptidase M42 family, Frv (Frv Operon Protein; Endo-1 4-Beta-Glucanase; Cellulase Protein; Endoglucanase; Endo-1 4-Beta-Glucanase Homolog; Glucanase; EC. 3.2.1.4) subfamily. Frv is a co-catalytic metallopeptidase, found in archaea and bacteria, including Pyrococcus horikoshii tetrahedral shaped phTET1 (DAPPh1; FrvX; PhDAP aminopeptidase; PhTET aminopeptidase; deblocking aminopeptidase), phTET2 (DAPPh2) and phTET3 (DAPPh3), Haloarcula marismortui TET (HmTET) as well as Bacillus subtilis YsdC. All of these exhibit aminopeptidase and deblocking activities. The HmTET is a broad substrate aminopeptidase capable of degrading large peptides. PhTET2, which shares 24% identity with HmTET, is a cobalt-activated peptidase and possibly a deblocking aminopeptidase, assembled as a 12-subunit tetrahedral dodecamer, while PhTET1 can be alternatively assembled as a tetrahedral dodecamer or as an octahedral tetracosameric structure. The active site in such a self-compartmentalized complex is located on the inside such that substrate sizes are limited, indicating function as possible peptide scavengers. PhTET2 cleaves polypeptides by a nonprocessive mechanism, preferring N-terminal hydrophobic or uncharged polar amino acids. Streptococcus pneumoniae PepA (SpPepA) also forms dodecamer with tetrahedral architecture, and exhibits selective substrate specificity to acidic amino acids with the preference to glutamic acid, with the substrate binding S1 pocket containing an Arg allows electrostatic interactions with the N-terminal acidic residue in the substrate. The YsdC gene is conserved in a number of thermophiles, archaea and pathogenic bacterial species; the closest structural homolog is Thermotoga maritima FrwX (34% identity), which is annotated as either a cellulase or an endoglucanase, and is possibly involved in polysaccharide biosynthesis or degradation.	5.83583e-135
NC_019954.2\|WP_013778390.1\|1367909_1369751_+\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|234630	PRK00095, mutL, DNA mismatch repair endonuclease MutL.	0

>NC_019954.2|WP_013778398.1|1375000_1375609_-|transcriptional-repressor-LexA
MYENLTHRQKQILDYIHNYFKTKGYPPSVREICVATNLKSTATVHSYLVQLEEKGYIKRDPQKPRAIEIMDTGIVIDKDVIQIPLVGKVTAGEPILAQENIENVFAFPKEMLPDANIFMLAVKGDSMIEAGILNGDYVMVQSTNTAKNGDIVVALLEDEATIKRFYKETDHIRLQPENRFMEPIIVKDLKILGKVVGLYRRF
>NC_019954.2|WP_013778397.1|1373681_1374992_+|methionine-gamma-lyase-family-protein
MKKVRANVFDEDIDRIAITDYGISLDIINKSRKVMEEIQSILKYIENVVEFNQVKILTAMKQSCLSDYHLMDSTGYGYNDTGRETIEEVYKNVFKAEDALVRPQIVSGTHSITLCLLGVLKPGDELLSATGTPYDTLKSVIWGDNCGSLKDYDIKYREASLLDGKPDFKAIKENINNNTKMVLIQRSRGYSLRPSLSITDIQKLIKYIKSLKNDVICFVDNCYGEFVETKEPIEVGADLCAGSLIKNPGGGIAPTGGYIAGKSELVKKCFYRLTAPGLDKNCGPSIFSNRLIAQGLFYAPNIVGEALKGAIFTAKIMEELGFEVYPRYNERRSDIVTAVILRNKDTLINFCRGIQKVGPIDSHVQPEPWAMPGYDHQVIMAGGSFIQGSSIEFSADAPIREPYAAYIQGGLSFYHVKLGILSGIQTLIDSGNLDIK
>NC_019954.2|WP_013778396.1|1373435_1373663_+|hypothetical-protein
MPYFNKILFTAFEISIFLFGYVLGRRMGKKEGVIEGMSLVPLDWRKQLFETSICPLCNQELNIKVNYDNVHNREL
>NC_019954.2|WP_144312824.1|1372809_1373406_+|hypothetical-protein
MSKLFILRKILSIFLTGCVIKLMDDYLDQDIDVLEDEPNLFTILELGGLPYALLLLSLAFFLDLVTALSLFLASFALGMGGNLTAKMPSGLYGYQESFIVLLLGFMSLKINMLSSMLIIAVIQLWDDVKDYKRNKINKKNLAFLLGKVECSLLAVICFLLSFYLDSIKAVSSIISTYLITYIIRLILIKNEKATSETI
>NC_019954.2|WP_144312823.1|1372226_1372817_+|50S-ribosome-binding-GTPase
MGKTNVGKTLFLINFAEYLGVKSFNIEFVNNTGSKTSEKIIPQTAVSYLVDKNPHKTRCLQSIIINVPVGKGKKKIKIVDTSGFIDGIHPNIEIRKAISQTLTTVRDSDIILHIIDASAVKNKDLPSSMGEVDYQIAQFAQLKKSYAILANKMDLPGANEGFEKIKQEFSGNLIFPISALHKTGFKEVKIFVMHNI
>NC_019954.2|WP_013778393.1|1371200_1372208_+|AAA-family-ATPase
MIDKIDNKMKNELNDHAKIHDMLISGLITTADALIMMTDLDSHKITFEKVSDEEEKLEDIMKELDELIGLSKVKNLVKEIQAFSEIQRKRAEEKLLAEPQVLHMIFKGNPGTGKTTVARLLGKIFKHIGILEKGHTVEVERADIVGEYIGHTAQKTRDQIKRARGGILFIDEAYSLARGGEKDFGKEAIDTLVKAMEDYKDDLIVILAGYKDEMDWFLQINPGLRSRFPIQIEFNDYSVDELMQIAKMMAEKRQYRFSPEALLQFEDILQSSMDNMFYNKLGNARLVRNMIEKAIRRQALRLVSQSKISRISREDLLQIEPEDIPVDISEFGGGH
>NC_019954.2|WP_013778392.1|1370737_1370995_+|RNA-chaperone-Hfq
MTKVQINLQDSFLNQIRKDNIPVTIYLVNGFQLKGMVRGFDNFTIVLDSDGKQQLVYKHAVSTIAPLRTINLNQGMIDQRKTDED
>NC_019954.2|WP_013778391.1|1369755_1370700_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MHKKFLVVIVGPTAVGKTEIAIEVAQKIDAEIISADSMQIYRYMDIGTDKPSLEERKRIPHHMIDIVDPDEEFSAVDFQVETKRHIQDIYQRHKIPLLTGGTGFYINSVCYDYTFSQVGKDTALRRQLQNEAQKRGNEYLYEELTRLDPKAAKKIHPNNLRRVIRALEVCLKTGIPFSYYEEKTKKQQSAYDLLMFGLTMPREELYQRINRRVFSMIENGLVDEVQQLLKMGYSKNLNSMQGLGYRQIIDYLDGNVTLEEAIRLIARDTRHYAKRQYTWFLRDKNILWLDISKEGKEKIITNIIRSIEGKMINT
>NC_019954.2|WP_013778390.1|1367909_1369751_+|DNA-mismatch-repair-endonuclease-MutL
MGKINILEQDIASQIAAGEIIERPVSVVKELVENSIDAGSKNIIVEIEKGGKKSIRVIDDGEGISRDDIRLAFERHATSKINVIEDIFHINTLGFRGEALASIAAVSNLSVTTKTRNEPIGTICKISAGVIEDVSETASKNGCLIEVKNLFFNTPARLKFLSSDTHENSRITDLITRFAMGNINISFRLIIDKKELFYSSGNGDYREVIAKVYGMDLAKQILYIEKAFDNGKIWGYISKPSFNRGNRTGQTFFVNNRFVKDLGLTFCLERAYKTMIPIRRFPIAIIFIDIDNSLVDVNVHPSKMEIKFQNENQVHHALFHAINETLKNHVLIPKETLSISPVKQSQQQISIETQVELTSDGLPDNEYDVSDSSNINNQTAATKEFVREAYTVIDVDAIKNKEHLQNDSYIPIESDETMQIIKKYEFQKILGQLFNTYIVVESKNRFYLIDQHAAHERILYEYYSKKYAKQLSNSQTLAAPYVLYLSAQEMMLLDNYKEDILKIGFDFSIFGSDSILIRSVPYIFNKPVDPITLRDALDQLSSNEYARYPSKERLIISMSCHAAIKAGDVLSPIEIQELLDQLKKTEVPYTCPHGRPTIIDITLNELQKKFKRI
>NC_019954.2|WP_013778389.1|1365287_1367897_+|DNA-mismatch-repair-protein-MutS
MDTPMIQQYKEIKDKYRDYIVFFRLGDFYEMFFDDAYICSKELEITLTSRDSDNKVPMAGVPYHAADQYIAKLVAKGYKVVICEQVEDPKLAKGIVKREVVKIVTPGTITDLNALEENKNNYLGCVFKNKHEFGLAFVDLMTGEFDITNLKSSYPYHEIINEVSRFSPRECLANHELSQEKSLNRKLKENLKLCFTFRDATYFDEQSALILLMSQFGEEKIKKLENRKPALIAAGACLRYLNETQKLNLSHINSISFYENHDFMVLDFICSKNLEITENLRDRKKTGSLLWVMDKTSTAMGARLLRKWLEQPLLDILKIKQRQDAIEELFNDFFLRSDLKEQLKNIYDIERLSGKLVCGNANARDLLAIKNTIKSLPQIKHILTRCNSKLLHQIYEQLDPLEDICLLLEKSIFEDPPLTIKEANVIKDGYNSEIDMLRKASREGKAWIADLERKERESTGIKSLKIGFNKVFGYYIEVTKSNLSMVPENYIRKQTLANAERYITEELKEYESLILNANEKLQELEYNLFCEIRDQLIKEIPRLKQSAYNLSLLDVLLSLAEVSYSNNYIKPEVNLSDEINIIDGRHPVVELTQKEELFIPNDTQIDCSDNLISVITGPNMAGKSTYMRQVALIVLMAQIGCFIPAKKAKIGIVDRIFTRIGASDNLALGQSTFMVEMTEVADILNNATNKSLLILDEVGRGTSTFDGLSIAWAVIEYIQKNLKAKTLFATHYHELTALKKLKGVKNYKITVKEKGDDVIFLRKIVPGEADKSYGIQVAKLAGVPNAVINRARKILVDLEQNQTQTQGELAISHIAACSDKSSQSTNEYQLNLSALKNEEIIEQIKSVNIDTITPLEALNFLFSIKKQLV
>NC_019954.2|WP_013778399.1|1377014_1378217_-|pyridoxal-phosphate-dependent-aminotransferase
MFISEKARNISPSPTLAVDAKAKRMKKEGHNIIGFGAGEPDFDTPEYIKLAAISAINQGFTKYTPVGGIEELKIAVSNYFEEEIGVKYASNQIIISNGAKQCLYNALYCLINEGDKVLIPSPYWVSYPEMVKLCGGISVFVPTTENNNFMLKAETLEKYIDEKTKVIIINSPNNPCGSVYPKQDLEQIAELAVKNNLFVISDEIYDKLIYDGLKHVSIATTYENILERTLLINGMSKSFAMTGWRIGFAAGPKQLIEAMENFQSHSTSNPNSIAQKASIEALTNLAKKQDTISKMVEEFSKRRTYMAKRINEMKNLSCNLPKGAFYVFMNISETFNKQYDGRIIKNSTDFAEVLLEKHNVAVVPGIAFGADDYIRLSYATSMENIKRGLDRIEEFVNALK
>NC_019954.2|WP_013778400.1|1378334_1379441_-|ATPase-AAA
MGEGCITRYFPGNNTPDGYCSFFDYILSWKQSRRIIILKGGPGVGKSTMIRKISNELVQKGLDIELLHCTADSDSLDGLIVKDYNIALVDGTSPHIIDPKFPGCIDEIINFGEYWNEANLFENKDIIFDLQEKVSNLYKRVYKYLKTSKMILDDLENIYSNAVINKLREAKIEEIVNQVFKKDVKVNNNKISFQRHMFASGITPEGSIHFLDELFGNVHQRFILSGNPGTGKSDLLKKILDHATSEGFDADVFHCPIDPKKIEHIIIKELDVGFVTSVKPHILSSIRQNDEIINMDFVLDYSKLKGLEEYIEYDKSVSRELFEKAIETLGNIKKVRNELEKIYASNMDFEAIKTVDEQILSKILRYIK
>NC_019954.2|WP_013778401.1|1379510_1379678_-|YpmA-family-protein
MGANSKLELIAKKEITYNDELYKLVDFLNKNLKNKQIIIGISKKNNKAIISIYET
>NC_019954.2|WP_013778402.1|1379701_1380472_-|5'/3'-nucleotidase-SurE
MNILITNDDGIYSEGLTALVQEMSEVANITVVAPDRERSATAHAITMHKPLRTEKIHIPNSKASGWKVNGTPSDCVKLALEALLDFTPDLVLSGINRGPNLGTDVIYSGTVSAAIEAALSGIPAIALSIISHNHNYENVSFNSAAQIVKKLCMQILERVFPEDSLLNINIPSVEQDEIVGVAITHLGTIKYKNSFDRRMDPRGKIYYWLAGEAIDNDEIGSDVWAVKNKYISITPLLFDLTKYEVIETLKKWDLQI
>NC_019954.2|WP_013778403.1|1380483_1381698_-|tetratricopeptide-repeat-protein
MTKKEVYDVLLNLKNAENNKNNKKKQYNIQFIWMSFLFWIGKYSKALCYINKLSKENNTVKIYCWKGVMYYFLKDYSNALLFLEKAEIIDPKNIDIKCLSAEIFFATAQLEKAEVRYRSLIGSDSKYQILGLYGIGRCLLKTNRYDEALGFFNKALLCIKQEDQHNLVKILNKKGLCLIELNKMEEARLCFEECLRNSPDDYNVQLNLALTLSKLKKFEEAAEIYKKILSKTPHNIIAINNCASCLAECDKNYEALEYYNIGLNIDPNNPDLLINKGYCLYKLGQYNIALECLNEAEKIVKNDIILYNNKALCLVALGKYDEALKLFNKLLDSNKCHSDDLLFNKAYCLVKKGMYSEALTCLANIKNKSSHNFDFYILKGICFEQLGNHEAAVKNFNKSLIIAR
>NC_019954.2|WP_013778405.1|1382378_1383359_-|M42-family-metallopeptidase
MKVLIKELTEVFGPSGSEEKIRRKIIDEIKPYADSITVDRLGNIIASKAGPGERLMLAAHMDEIGIIITNIDEKGFLRFSNIGGISPFTLIGQRVVFANGTLGVIGMEKMDDIKNLKINKMFIDIGVKSKEDAFKRVNIGDTGVYDKECSIIGDHIISNSLDDRVGCAILIEVLKRLKNPNYNLFVVFTVQEEVGLRGAKTSAYGVNPDFAIAVDVTDTGDTPESEKMAVELGKGPAIKVKDSSVICHPEVKKALIDAAERKSTPFQLEVLEKGGTDTGAIHLTRSGVPSGALSIPTRYIHTPTEMVNFNDIVQSVELLIELIEGK
>NC_019954.2|WP_013778406.1|1383360_1384374_-|M42-family-metallopeptidase
MLLKQLSNAFGVSGAEGEVRDIIRQNLCNVGKSKTDALGNLFIEKTSKCNKPSLMLCAHMDEVGFMIKYIENNGLLRFDTVGGIDERILVSKNVVVGSNKIKGVIGAKAIHLQDPNEREIPLKSKNLYIDIGAKDKEDAETKVKIGDYAVFDTEFSSVDNIIIGKALDDRIGCYIISEILKKTYNVPITGVFTVQEEIGLRGSAVAAYTVNPDFAIVVEGTFASDVPDTKEEEYCTTLGKGPAITFMDRTYIAEKNLINWIIEVADNHNIPYQYKRTTFGGTDGGRIYTTYQGIPTVIFSVPCRYIHSPIAIANFKDIEHTISLIDVIIHYVQERGI
>NC_019954.2|WP_013778407.1|1384364_1385414_-|M42-family-metallopeptidase
MDLSEVLVRLIEPAIPSGSEFQNNELIKEVFSNYCDEVKCDKFGNIISLKRGFSPEYKIMLAAHMDEIGLMVKHIDDKGFVHFAFIGGVDQRILPAQEVIIHGRKNILGIIGSKPPHIQETDERKKAVKAENMFIDTGLTPQDVQRYITIGDFITFKRKPVELLNNCFSSNALDDRAGIAVMLVALEELSKLKHAVSVYAVATAQEEVGLRGAIVSSYGICPDIGIAIDVCHGNMPDTPEYNTQKLGLGPALALGPNIHPKLYNRLKQIAEDYKIPYQLDPQPSATGTDAWAIQITKEGIPTALVSIPLKYMHTTVETLCLDDIKMSGRLLALFIASLCKDFMEGLACY
>NC_019954.2|WP_144312798.1|1386428_1387232_-|protein-glutamate-O-methyltransferase-CheR
MCKGVSSLNYDEFTVEIKKLCDIDLSNYKEKQMKRRIDSLIKRNGHESYDSYLTQLKKSEQHLKEFLGYITINVSEFFRNPAQWQILEQELIPELISRKNTLKIWSSACSTGEEPYSLVMLLDKMGLINRASIIASDIDEEALEQARIGIYTSKGIANVPEEMVKANFIKENDNYVIKDKIKKAVDFKIINLLEDPFPSNCDLILCRNVMIYFTEKAKEKLYKKFYNALSDNGIFFVGSTEQIMMPQKYGFISRKHFFYQKIVGGNK
>NC_019954.2|WP_013778409.1|1387457_1387832_-|S-adenosylmethionine-decarboxylase-proenzyme
MKNLGRHILAEIYDCDPTILNNSGLIEEILVKAALEAGAEVREVAFHKFSPQGVSGVVIISESHLTIHTWPELGYAAVDVFTCGDRVNPWDACNYISKGLCAKHMDATEVKRGLFDMPVKAINF

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Crispr_ID: NC_019954_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019954_8

1767715-1767831

Orphan

Consensus_repeat	Method
ATCGGTTTTATCGGATAGATCTTTGATTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019954_8

>merge|NC_019954|8|1767715-1767831|CRISPRCasFinder
ATCGGTTTTATCGGATAGATCTTTGATTTCCTTATGAACCATATCAAATTTTGCATCGGTTTCCTTACGGTTGGCTTCAAACTTAGTATCGGTTTTATCGGATAAATCTTTGATTTC

>NC_019954|8|8|1767715-1767831|CRISPRCasFinder
ATCGGTTTTATCGGATAGATCTTTGATTTC	CTTATGAACCATATCAAATTTTGCATCGGTTTCCTTACGGTTGGCTTCAAACTTAGT
ATCGGTTTTATCGGATAAATCTTTGATTTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019954.2\|WP_049779037.1\|1769123_1769348_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182396
NC_019954.2\|WP_013778760.1\|1760259_1761414_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|377505
NC_019954.2\|WP_013778765.1\|1766915_1767143_-\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013778774.1\|1774789_1775473_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_019954.2\|WP_013778773.1\|1773615_1774803_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NC_019954.2\|WP_041591439.1\|1756662_1759506_-\|sigma-54-interacting-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226443
NC_019954.2\|WP_013778769.1\|1768601_1768778_-\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013778775.1\|1775472_1776699_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_019954.2\|WP_015295585.1\|1770467_1770893_+\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013778756.1\|1755542_1756016_-\|PTS-sugar-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|377139
NC_019954.2\|WP_023211538.1\|1770909_1771257_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379665
NC_019954.2\|WP_013778776.1\|1776914_1777979_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|372253
NC_019954.2\|WP_013778757.1\|1756028_1756448_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NC_019954.2\|WP_013778761.1\|1761577_1762774_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NC_019954.2\|WP_013778762.1\|1762806_1764390_-\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|379311
NC_019954.2\|WP_023211536.1\|1769340_1769532_-\|antitoxin-VbhA-family-protein	unknown	unknown	gnl\|CDD\|212155
NC_019954.2\|WP_013778763.1\|1764625_1765381_-\|arginase-family-protein	unknown	unknown	gnl\|CDD\|212516
NC_019954.2\|WP_013778759.1\|1759597_1760245_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NC_019954.2\|WP_013778772.1\|1771899_1773435_-\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NC_019954.2\|WP_013778764.1\|1765571_1766660_-\|fructose-1,6-bisphosphatase	unknown	unknown	gnl\|CDD\|376679

Protein	Function_ID	Function_description	E-value
NC_019954.2\|WP_049779037.1\|1769123_1769348_-\|hypothetical-protein	gnl\|CDD\|182396	PRK10347, PRK10347, putative adenosine monophosphate-protein transferase Fic.	9.79669e-07
NC_019954.2\|WP_013778760.1\|1760259_1761414_-\|sensor-histidine-kinase	gnl\|CDD\|377505	pfam05384, DegS, Sensor protein DegS. This is small family of Bacillus DegS proteins. The DegS-DegU two-component regulatory system of Bacillus subtilis controls various processes that characterize the transition from the exponential to the stationary growth phase, including the induction of extracellular degradative enzymes, expression of late competence genes and down-regulation of the sigma D regulon. The family also contains one sequence from Thermoanaerobacter tengcongensis which is described as a sensory transduction histidine kinase.	1.36284e-63
NC_019954.2\|WP_013778773.1\|1773615_1774803_-\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	8.97891e-78
NC_019954.2\|WP_041591439.1\|1756662_1759506_-\|sigma-54-interacting-transcriptional-regulator	gnl\|CDD\|226443	COG3933, COG3933, Transcriptional antiterminator [Transcription].	2.7951e-89
NC_019954.2\|WP_023211536.1\|1769340_1769532_-\|antitoxin-VbhA-family-protein	gnl\|CDD\|212155	cd11586, VbhA_like, VbhA antitoxin and related proteins. VbhA is the antitoxin to VbhT. The VbhT toxin of the mammalian pathogen Bartonella schoenbuchensis is responsible for the disruptive adenylation of host proteins. VbhT also induces FIC-domain-mediated growth arrest in bacteria; it is inhibited by this antitoxin which binds to block the ATP binding site of the VbhT FIC domain.	6.99971e-05
NC_019954.2\|WP_013778775.1\|1775472_1776699_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.3477e-41
NC_019954.2\|WP_013778776.1\|1776914_1777979_-\|ABC-transporter-permease-subunit	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	7.36761e-05
NC_019954.2\|WP_013778756.1\|1755542_1756016_-\|PTS-sugar-transporter-subunit-IIB	gnl\|CDD\|377139	pfam03830, PTSIIB_sorb, PTS system sorbose subfamily IIB component.	7.89456e-47
NC_019954.2\|WP_023211538.1\|1770909_1771257_+\|hypothetical-protein	gnl\|CDD\|379665	pfam14659, Phage_int_SAM_3, Phage integrase, N-terminal SAM-like domain. This domain is found in a variety of phage integrase proteins.	9.38839e-06
NC_019954.2\|WP_013778757.1\|1756028_1756448_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	2.15786e-37
NC_019954.2\|WP_013778761.1\|1761577_1762774_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NC_019954.2\|WP_013778762.1\|1762806_1764390_-\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	1.50773e-08
NC_019954.2\|WP_013778774.1\|1774789_1775473_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	5.1289e-117
NC_019954.2\|WP_013778763.1\|1764625_1765381_-\|arginase-family-protein	gnl\|CDD\|212516	cd09990, Agmatinase-like, Agmatinase-like family. Agmatinase subfamily currently includes metalloenzymes such as agmatinase, guanidinobutyrase, guanidopropionase, formimidoylglutamase and proclavaminate amidinohydrolase. Agmatinase (agmatine ureohydrolase; SpeB; EC=3.5.3.11) is the key enzyme in the synthesis of polyamine putrescine; it catalyzes hydrolysis of agmatine to yield putrescine and urea. This enzyme has been found in bacteria, archaea and eukaryotes, requiring divalent Mn and sometimes Zn, Co or Ca for activity. In mammals, the highest level of agmatinase mRNA was found in liver and kidney. However, catabolism of agmatine via agmatinase apparently is a not major path; it is mostly catabolized via diamine oxidase. Agmatinase has been shown to be down-regulated in tumor renal cells. Guanidinobutyrase (Gbh, EC=3.5.3.7) catalyzes hydrolysis of 4-guanidinobutanoate to yield 4-aminobutanoate and urea in arginine degradation pathway. Activity has been shown for purified enzyme from Arthrobacter sp. KUJ 8602. Additionally, guanidinobutyrase is able to hydrolyze D-arginine, 3-guanidinopropionate, 5-guanidinovaleriate and L-arginine with much less affinity, having divalent Zn ions for catalysis. Proclavaminate amidinohydrolase (Pah, EC 3.5.3.22) hydrolyzes amidinoproclavaminate to yield proclavaminate and urea in clavulanic acid biosynthesis. Activity has been shown for purified enzyme from Streptomyces clavuligerus. Clavulanic acid is the effective inhibitor of beta-lactamases. This acid is used in combination with the penicillin amoxicillin to prevent antibiotic's beta-lactam rings from hydrolysis, thus keeping the antibiotics biologically active.	1.6182e-11
NC_019954.2\|WP_013778759.1\|1759597_1760245_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.3428e-74
NC_019954.2\|WP_013778772.1\|1771899_1773435_-\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NC_019954.2\|WP_013778764.1\|1765571_1766660_-\|fructose-1,6-bisphosphatase	gnl\|CDD\|376679	pfam01950, FBPase_3, Fructose-1,6-bisphosphatase. This is a family of bacterial and archaeal fructose-1,6-bisphosphatases (FBPases). FBPase catalyzes the hydrolysis of D-fructose-1,6-bisphosphate (FBP) to D-fructose-6-phosphate (F6P) and orthophosphate and is an essential regulatory enzyme in the glyconeogenic pathway.	0

>NC_019954.2|WP_013778765.1|1766915_1767143_-|hypothetical-protein
MEEIVKVAILENEIEAKLLSSLLKEYKIPHFIGTYHDAAYDGIFQTQKGWGFVEAPTYYKSQILDILSDIRKGSN
>NC_019954.2|WP_013778764.1|1765571_1766660_-|fructose-1,6-bisphosphatase
MGSKITLSVIKADVGGFVGHGSVHPDMLKNAEEILEQQGKELLVDFFVTNVGDDINLILTHKEGINSEKVHKLAWNTFLSCTEVAKSLKMYGAGQDLLSDAFSGNIKGMGPGIAEMEFEERPSEPVIIFMADKTEPGAWNLPLYKIFADPFNTIGLVIDPKMHSGFCFEVLDLVEDKKVTFSCPEELYDLLIFLGASNRYVVKSVYTKNKEIAAVSSTQKMNQMAGRYVGKDDPVLIVRCQSGLPAVGEVLEPFANPHLVTGWMRGSHYGPLIPVSQKQAVPTRFDGPPRAIAMGFQLANGRLIGPQDLFADVAFDRARQKALKAADYIRQMGPFEPHRLPLDEMEYTTMPQVMEKLKNRFK
>NC_019954.2|WP_013778763.1|1764625_1765381_-|arginase-family-protein
MDFGVNIIKTDNSLDYQKKLLEEADTIIDLTSYKGLRFCSYSKILDEISNKLRKLSLGICFLGSGDFHHLSFSLISNISVKPILLLIDYHADMYETFPDMISCGSWAMQALKEEKVRKCIVVGVDAKDPAINKFKFQDEYVTFFPINIPQKLMIPKVLDELSKSQDPIYISIDKDVLCKEDAATGWEQGLMHLDELLELLLHIKKTGKVIGVDVCGEWVLPIDEIMFSIQDRYSMQLNQIANVKILERMLH
>NC_019954.2|WP_013778762.1|1762806_1764390_-|HEAT-repeat-domain-containing-protein
MQKRIQEKAPKVDYRLLYKKQILDYLESLKDTEQTIWQMDESMKRLFRIGEQVIPVCLAKLRENDEEIAPIVCYALEFANDYSVVEPLMDILIMPNVSDRIKARILAVLTHYGIDASELPLEIIMEDFDKMASDSMAEMLEDIESDPFLIPYILDDLDEFSLEMKLAYIKDLGAQKDERAIPILEIMASVDDYPVAHEAIKALGQIKSGKALYVLYKLATKSAEEDIQRIAHRESQRLKFNGISMEFFEPWENLQNPAKVFISSIDGIGSRVLWIAWKNPFKSRKLSFMNLLISADMGVRDCWGVSNITTREFNSSVKDFSRTTVVTKCDLDYAITLLGDALFFNKTKDYPIPYQFYFWKHLLEQNCRINCEPYYPQFTGYDLELIEKDQECFKSTFDLFNHSFFNDWFIAHPRVYDYAEENKSRKGYLIKKMTYQKAEKLFARFTEELIEPNADKVKRMLELSADFLDKAGQTEIAKTALCAFLHMDIKPLHHHPFIQRMIIESIKVALNNMKNGFDMRFNPGDFE
>NC_019954.2|WP_013778761.1|1761577_1762774_-|methionine-adenosyltransferase
MGKNFLFTSESVTEGHPDKICDQVADAILDSILSKDPLARVACEVAVTTGLVMVMGEITTDCYVDIPSVTRETVKQIGYTRAKFGFDCDTCAVITSINEQSPDIAMGVNCAYEARQSMDNADEFDKIGAGDQGMMFGYAVNETSELMPMPISLAHKLARRLADVRKNDVLPFLRPDGKTQVTVQYEDSKPVRVDKIVVSAQHSSSVELLTLEEGIIEEVIKKIIPAHLMDKKTQIYVNPTGRFVVGGPHGDSGLTGRKIIVDTYGGYGRHGGGSFSGKDPTKVDRSASYAARYVAKNIVAAGLASKCELQLAYAIGVSRPVSVMIDTFGTGILPDEEIEKLVINNFDLRPGAIIRDLDLRRPIYRQIASYGHFGRDELDLPWEKVDKAEILKNQAGSL
>NC_019954.2|WP_013778760.1|1760259_1761414_-|sensor-histidine-kinase
MHKTQINIEYLNEVINSTIDAIEKGQKEIFNIFEHARQECERIQRELEDLKAQVKDRIREVDNLAKLEKSAKFKLMIVSRDFEKHSEEDIKAAYEETKDIQIRLSIERQKEIQLREKRDDLERNLKSMLNILNQSEHLMMQLGVALGFLKGDLKDMSGHISDINERRNLAAKIIKAQEEERQRVARDIHDGPAQTLANIVIQTDICERLMERDLNEAKKELNQLKKIVRSSLQELRKIIFNLRPSSLDNLGLQAVTKRYCEEFQEETGIRTEFRFFGDKTRLGSEIEVTIFRLIQEALTNVKKHSKAKNCIVKLEFGDGKANLVIADDGVGFEVSTKDSSDSEQHFGIMTIKERVALVDGSFNIESEPGQGTKLFATIPFANRL
>NC_019954.2|WP_013778759.1|1759597_1760245_-|response-regulator-transcription-factor
MEKITVVLADDHVLMRKGLRKILEMEEDIEVIDEASDGIEAIEKVMEKKPQVLLLDINMPKLNGIEVTKSLREKNVDSQIVILTIYDDREYLLELLKLGISGYVLKDIEPQGLIEAVRSASRGETYIQPNLTRALVAEYNRLTQPVSNNDVRKNLTAREKEVLADIAKGMSNREISIDLGISEKTVKNHVSSILRKLNLMDRTQAAVFAIKNRLV
>NC_019954.2|WP_041591439.1|1756662_1759506_-|sigma-54-interacting-transcriptional-regulator
MTRKEKVFIALKNLSSDVSAAKIAEDLSFGFDAETISKVTEIDRSNVSRELNELVRENKAIKIIGRPVKFFAKSCLEEILQIKYEGDGVIEDVNNFLHNTNFANDELNTKENDPFARIIGETGSLELAIKQAKAAILYPPRGLHTLITGPTGVGKTTFAEVMYQYAIYNGNISKDAELIVFNCSEYADNPQLILSQLFGYVKGAFTGANQDKAGLIESADGGILLLDEIHRLPPEAQEMLFLLMDKGIYRRLGETDKYHTASILIIGATTENLNSVLLQTFLRRIPMTINLPSLEDRPLNERLEFIETFFMSEASNVKVPIRIHKDVIRAFLLYDCYGNIGQLKGDIQLLCARGFLDYKTYNKKEIEINIHLLPEHIYSGLLSRHKDYSEVFELLEYGKDYYIYKPDDKKLAETINLNSFDVSDNLYKEITKKYNHYLNIGFSNDKISEIINNDIIKYLKKLLKKYDHNTEKALLDKNELFKIINPKVYNAAETALILAEQKLNKHFSNRAIIGLAMHISALMERIADKSLIYYEEINKIALNNPSEFKVAKMIREVLQQELGISIPTGEIGFLTMFLSAVDTGDDYSKIGVIVLAHGEATATSIADVANTLLATEHCKAIDMPLDMKVDNALEKTIEMVKKVDEGKGVLLLVDMGSLTAFAEIITQKANVLTKSIENISTPIVIEAVRKSLLPEMTLSVLVEDLNRANPYIGRIISGDIKNRVNISSSKTILTTCISGMGAAVKIAQLLKNTLNFVDEYNVKIQPVNKAENLDNILDKNGYDDVIAVVGTVDLHIPQVPFIPIDELIIGDGVRKLEKSITGSNNYIKSKKQSEENVFINMLEELLTFLNPIKAYNVVNDSYTATIKLLGIKDSARIKSRYIFHNCCMIERLIQNDILPYNNIDELIQKKMSIYEKVKLSLANIEEAFGITVPDTEIGYIIDLLDTQ
>NC_019954.2|WP_013778757.1|1756028_1756448_-|PTS-sugar-transporter-subunit-IIA
MLGILIVTHSNFGKELLRSAELIVGRQENIETLGLEHGDSVEELYKKVKDSLKKLDRGEGVLILTDLFGGSPSNVTAAAMKENNIKVESISGVNLPMLIEALDLRNTTDLECIIDKIIQTGIFGIKNIKLELKEKSNSA
>NC_019954.2|WP_013778756.1|1755542_1756016_-|PTS-sugar-transporter-subunit-IIB
MADITMVRVDERLVHGQIIIKWLQAKNANKIIIVDNELCKDPIMGNFLSMTVPQNVNLEIYDIYEAVETLNASESNDKAIILLKNLYLVKFMHQKGVKIKEINIGRIPSGPGKKKIHQNVFLSDEDIDAIEYFREKAVPIIVQMVPDSLPILIYDVI
>NC_019954.2|WP_013778769.1|1768601_1768778_-|hypothetical-protein
MTKGEIDKSLEYVKGTMAYEDMELPDDTLEIYEKYLKEKITDSRARELLIKKNLSKEV
>NC_019954.2|WP_049779037.1|1769123_1769348_-|hypothetical-protein
MLDPYLFPDSEVLKNKLDIKEKDKLEIVEAEYTSLLIGAIAEENTIKGDFSFEHLCQMHCYIFRIYMNGPGNQE
>NC_019954.2|WP_023211536.1|1769340_1769532_-|antitoxin-VbhA-family-protein
MGMSKEKAWNYALGIIKVAGLEPSPEFLKLVDKEKRGEITMEDIKRILDKKYKMKEERDGKNA
>NC_019954.2|WP_015295585.1|1770467_1770893_+|hypothetical-protein
MYLQMLEKAIMLLQKYSITEFPIRIDVIDEITFKEGIKLQITKYLKKAFYYEDSKEKIIYLGHKVKATYQQREYILHETAHMYHCGNTALLPHLVVDKNESQAEDFEREFLLRQSRSPNMTFEMLVDLYYEDSTHRVRWSN
>NC_019954.2|WP_023211538.1|1770909_1771257_+|hypothetical-protein
MIDTHVLPVFKQKVISEITKADIRRWQNLMLKKKNPRNDKPYKPTYLHQLSAILNFAVEFYSLPKNPCSRVKSIGKKRADEMNFWTLDQFNEVTACEELPAYRVAFMMLYWAGNG
>NC_019954.2|WP_013778772.1|1771899_1773435_-|glutamine-hydrolyzing-GMP-synthase
MENTRETVVILDFGGKYAQMVARRVREAQVYCELLSYKTPWEEILQRQPKAIILSGGPSGIFTDNAPACDERVFNGDVPILAIGYGMQLMVKSLGKDIKPGSKREIGPADLLVDIDQGLFQGMGRKMTVFMDSGDLPASLPEGFEVLAHTQKTPFAAIGNGKNLYGVQFHPEESHTQCGREILNNFLFGIAGCSGTWSTRAFIQEQIKLIKDKVADKKAICALSGGVDSSVAALLVHKAIGDNLTCIFVDHGLLRKNEAENVIKTFKDKFHMNLIAVDASKRFLSKLKGVTDPEKKRKIIGEEFIRVFEEEAAKLGKVNFLVQGTVYPDVIESVNPIGGAVKSHHNVGGLPEDLEFELIEPLRELFKDEVRKIGLELGLPEELVYRQPFPGPGLAVRVLGEVTEDKLSILREADFIVTDEIKKAGLYKELWQAFAILPNIQSVGVSADRRTYTHTIAVRAIVSEDGMTGEWARLPHDLLDSISTRITSEVEGVNRVVYDITPKPPSTIEWE
>NC_019954.2|WP_013778773.1|1773615_1774803_-|ABC-transporter-permease
MNFFESIVIAWESIIANKMRSLLTMLGIIIGVSSVITISALGQGGQFAISKEMDAFGANRFGVYYKYNSDNPLTQADFFTIQDVKAIKDISPVVENIAPVSWDSANVRLKGKQIGVQIAATTSDYIKIANLKLDAGRFLNHEDDNGKKHVAVISESLAKELFNSSGAVGEKIMVGNQPFKVIGVLRREETVFSGQDNKLMYIPISTYFSISGSDWVDNIEGKAISQADVDTAIEHSLSILHRRHHNTDKYQAWNSQKEMDSVNKVTGIITIIISAIAGISLLVGGIGIMNIMLVSVTERTREIGIRKALGAQETDIMMQFLIESLVLSFFGGIIGMLLGFGVSKIIAGFIKLPTVLSWQMIALAFTFSAGVGVCFGLYPARKAALHDPIDALRYE
>NC_019954.2|WP_013778774.1|1774789_1775473_-|ABC-transporter-ATP-binding-protein
MILIENMAKVYRNGENKVSALRDVNLHVKKGEFVAIMGPSGSGKSTLMNILGCLDKPTSGEYYLDGKSIAQLNSRQLAHTRNKKIGFVFQNFNLLPRINSLRNVEIPMIYARVAPNERRKKAMEALKSVGLEDRWHHKSNELSGGQKQRVAIARALVNSPEIILADEPTGNLDSKSGAEIMDIFADLHMKGTTIVLVTHENEIARYAQKVVIFRDGRKVEELSSELL
>NC_019954.2|WP_013778775.1|1775472_1776699_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MNKRKKILIIAVILLIGVAFFIIRAKRQPNTAMALPTVKAIKGDISSKITALGNVETRQKQEVYSGIQGMVEYIAEEGQQVKKGDVVLKIDDGELKLELEQAQSKVKQQNVELSRLLGGPRPEELKKARIKYQEALTSYEAALEDYEKNQGLFNEGAISENEYINIKRELDVKKNQLAIMEVELSLLENPDEHEIALKQAALEEAEKSLANITKKLDKTIILAEFDGIVIKQEIKQGMTVSSGNLLLSIGSPDDLQIDIGVNEYDASNIKVGQKAIITGDGFGDKIYKGEVVKIAPSASTIQTSRGNETTVKATIKVNDPDENIKPGFSTTAEITIEDKQGAVLLPLECVISGEKGKKVMLVKDGAISEREVKTGIENELYTEITYGISEGDEVLQNPSANSSFEGDA
>NC_019954.2|WP_013778776.1|1776914_1777979_-|ABC-transporter-permease-subunit
MTLQTLPFNKALLKKDWKMTKWLCFAVAGILFFTMTLGVINTYNNYQRTIQEMEKHPEWYAGYDKDEYKAELKNLLQDKFKQLSGMGAMLVVFTPMAAAALLFGEEKRKKTFEILATMPFSRTEIFFNKVVIAFVNAILPFLINAVIMAAALWFSKGLRDFYSAGMVMSWFGADAFRLFVILSFSLLFASLTGTSISQLVLTIIFFIFPIGFTGLLYMNMAVWGYRISVIDEFLNIFGSYTMPGILSNIKEVPITFHLISAIIMLAAAKLLFDRNKLERSGETLEFETIETFFKFGVAVCTSMLIGVIVTGCAGSFIYFTNNVPRIFTIIGYIIGIFLGWFVASYSIKTNRAKV

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Crispr_ID: NC_019954_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019954_9

2541765-2541891

Orphan

Consensus_repeat	Method
AAAAAAGAAGAACCAACCGGTTAAGGTCAGTTCTTCTTG	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of NC_019954_9

>merge|NC_019954|9|2541765-2541891|CRISPRCasFinder
AAAAAAGAAGAACCAACCGGTTAAGGTCAGTTCTTCTTGATTGCTACTATTTCTTATAACACAGAGGGACTGTCCCCTTGTGTTTAATAAAAAAGAAGAACCAACCGGTTAAGGTCAGTTCTTCTTG

>NC_019954|9|9|2541765-2541891|CRISPRCasFinder
AAAAAAGAAGAACCAACCGGTTAAGGTCAGTTCTTCTTG	ATTGCTACTATTTCTTATAACACAGAGGGACTGTCCCCTTGTGTTTAAT
AAAAAAGAAGAACCAACCGGTTAAGGTCAGTTCTTCTTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019954.2\|WP_013779478.1\|2554432_2555071_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|316044
NC_019954.2\|WP_013779474.1\|2544246_2547246_-\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|306825
NC_019954.2\|WP_013779472.1\|2540877_2541669_-\|ImmA/IrrE-family-metallo-endopeptidase	unknown	unknown	gnl\|CDD\|368753
NC_019954.2\|WP_013779468.1\|2538590_2538914_-\|HTH-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NC_019954.2\|WP_013779475.1\|2550092_2551175_-\|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein	unknown	unknown	gnl\|CDD\|225224
NC_019954.2\|WP_015295929.1\|2557393_2558002_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|273579
NC_019954.2\|WP_013779476.1\|2551305_2552562_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NC_019954.2\|WP_013779469.1\|2539367_2540090_-\|ImmA/IrrE-family-metallo-endopeptidase	unknown	unknown	gnl\|CDD\|368753
NC_019954.2\|WP_013779473.1\|2541904_2544163_-\|Ig-like-domain-containing-protein	unknown	unknown	unknown
NC_019954.2\|WP_013779462.1\|2534163_2534358_-\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013779467.1\|2538320_2538572_-\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013779464.1\|2536331_2536865_-\|DUF2815-family-protein	unknown	unknown	gnl\|CDD\|378531
NC_019954.2\|WP_013779463.1\|2534373_2536332_-\|DNA-polymerase	unknown	unknown	gnl\|CDD\|176479
NC_019954.2\|WP_013779482.1\|2558040_2558736_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NC_019954.2\|WP_013779477.1\|2552625_2554233_-\|CTP-synthase	unknown	unknown	gnl\|CDD\|235437
NC_019954.2\|WP_013779480.1\|2557023_2557374_-\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013779466.1\|2538024_2538306_-\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013779470.1\|2540104_2540473_-\|hypothetical-protein	unknown	unknown	unknown
NC_019954.2\|WP_013779471.1\|2540476_2540863_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379262
NC_019954.2\|WP_013779479.1\|2555224_2556934_-\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964

Protein	Function_ID	Function_description	E-value
NC_019954.2\|WP_013779478.1\|2554432_2555071_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|316044	pfam13483, Lactamase_B_3, Beta-lactamase superfamily domain. This family is part of the beta-lactamase superfamily and is related to pfam00753.	1.40528e-68
NC_019954.2\|WP_013779472.1\|2540877_2541669_-\|ImmA/IrrE-family-metallo-endopeptidase	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	1.72417e-05
NC_019954.2\|WP_013779468.1\|2538590_2538914_-\|HTH-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.55168e-11
NC_019954.2\|WP_013779475.1\|2550092_2551175_-\|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	1.05956e-65
NC_019954.2\|WP_015295929.1\|2557393_2558002_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|273579	TIGR01367, Orotate_phosphoribosyltransferase, orotate phosphoribosyltransferase, Thermus family. This model represents a distinct clade of orotate phosphoribosyltransferases. Members include the experimentally determined example from Thermus aquaticus and additional examples from Caulobacter crescentus, Helicobacter pylori, Mesorhizobium loti, and related species. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis].	2.13137e-73
NC_019954.2\|WP_013779469.1\|2539367_2540090_-\|ImmA/IrrE-family-metallo-endopeptidase	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	1.42607e-10
NC_019954.2\|WP_013779474.1\|2544246_2547246_-\|S-layer-homology-domain-containing-protein	gnl\|CDD\|306825	pfam00395, SLH, S-layer homology domain.	4.69215e-07
NC_019954.2\|WP_013779464.1\|2536331_2536865_-\|DUF2815-family-protein	gnl\|CDD\|378531	pfam10991, DUF2815, Protein of unknown function (DUF2815). This is a phage related family of proteins with unknown function.	5.60376e-99
NC_019954.2\|WP_013779463.1\|2534373_2536332_-\|DNA-polymerase	gnl\|CDD\|176479	cd08642, DNA_pol_A_pol_I_A, Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication. Family A polymerase (polymerase I) functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication. DNA-dependent DNA polymerases can be classified in six main groups based upon phylogenetic relationships with E. coli polymerase I (classA), E. coli polymerase II (class B), E.coli polymerase III (class C), euryarchaaeota polymerase II (class D), human polymerase beta (class x), E. coli UmuC/DinB and eukaryotic RAP 30/Xeroderma pigmentosum variant (class Y). Family A polymerase are found primarily in organisms related to prokaryotes and include prokaryotic DNA polymerase I ,mitochondrial polymerase delta, and several bacteriphage polymerases including those from odd-numbered phage (T3, T5, and T7). Prokaryotic Pol Is have two functional domains located on the same polypeptide; a 5'-3' polymerase and 5'-3' exonuclease. Pol I uses its 5' nuclease activity to remove the ribonucleotide portion of newly synthesized Okazaki fragments and DNA polymerase activity to fill in the resulting gap. A combination of phylogenomic and signature sequence-based (or phonetic) approaches is used to understand the evolutionary relationships among bacteria. DNA polymerase I is one of the conserved proteins that is used to search for protein signatures. The structure of these polymerases resembles in overall morphology a cupped human right hand, with fingers (which bind an incoming nucleotide and interact with the single-stranded template), palm (which harbors the catalytic amino acid residues and also binds an incoming dNTP) and thumb (which binds double-stranded DNA) subdomains.	0
NC_019954.2\|WP_013779482.1\|2558040_2558736_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	9.0897e-112
NC_019954.2\|WP_013779477.1\|2552625_2554233_-\|CTP-synthase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NC_019954.2\|WP_013779476.1\|2551305_2552562_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	3.41101e-56
NC_019954.2\|WP_013779471.1\|2540476_2540863_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.51504e-09
NC_019954.2\|WP_013779479.1\|2555224_2556934_-\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0

>NC_019954.2|WP_013779472.1|2540877_2541669_-|ImmA/IrrE-family-metallo-endopeptidase
MIDLDFRRKSNGVPILSKAEIETLAEMVIKDYNPKLLEEPGSLDVEDFAEGYADLEMDYKDLTHNQSILGMTVFCNCYIPIYNAEENKAEEIPVDEGTIIVDNSLLNDGQLRRGRFTLGHEISHWLLHRHIYMIDKNQLSLFDFLPNDTQPVIKCRSTDIENSGKRQFETDDDWMEWQADYMASALLMPKKAFTRAVKEKFKAMGLKKDYFEVGTDFELNLRAEVLPYELADLFDVSVTAVRIRLKGLNFIRKQQENNQSLFG
>NC_019954.2|WP_013779471.1|2540476_2540863_-|helix-turn-helix-domain-containing-protein
MNKFGEFITARRKAEKITLRKMAELLDFSPAYWSDIEKGRRNPPNINKLEELARILKLTSEEKYHMIDLASEDRDEIPMDLPDYIKDSGLARTALRKARRMDEKEGSSDITERAWKEFIKTLDEERGK
>NC_019954.2|WP_013779470.1|2540104_2540473_-|hypothetical-protein
MNNLFKDMLAEHFEQEIYDFLQDHIMNNYDQYDLTRRANEVNEVLEASLDLAEVLRVYNIKQDGSDVAFNMLVSCDIEIGDYFAGENITESVCQWFELSCSAVLENATLTDFSIDGIEAYNK
>NC_019954.2|WP_013779469.1|2539367_2540090_-|ImmA/IrrE-family-metallo-endopeptidase
MNLSKDLVPIISKKDMDIEAAKFLEKYCPAALEKPMPIPVEDIAEFKMGLEIDYANLDKNCDTLGMVLFSNGMVELYDKETKKYFKRPYEKGTILVENDLVELDNKGRERFTIAHELVHWDKHQLRFMTLSYQDKTLAKACRCPSEKVHRPKKPDEWVEWQADNLAAAILMPAEMFRLKAEEIKNKYRGRVGTKINEFMWKGFSPGMIAEFITDELADFFQVSKQAAGIRIQTLGINLPK
>NC_019954.2|WP_013779468.1|2538590_2538914_-|HTH-domain-containing-protein
MGPNERRMEIIEALCRRRQDTMSNLAIEFGVSVRTIKNDIDILSLSYPIETIRGRYGGGVRVADGYYLHKKYLKPEQQELLERLCANLSGNDLMVMNSIIKDFALNA
>NC_019954.2|WP_013779467.1|2538320_2538572_-|hypothetical-protein
MSDLHYALAEELEKLAAGYRALARGEVKPYEANIQDISIVLTEKIKKGKVSEIKALLKKYGATKLVEVKKKDYEAFYKEAKHL
>NC_019954.2|WP_013779466.1|2538024_2538306_-|hypothetical-protein
MSKMKLALDVVENLRSLADSIEALTDVVEGNEPKEKVEDNLPTLEQVRAKLAALTQSGKQAEVKALITKYGAKKLSEIPEDKYPELLKDAEGI
>NC_019954.2|WP_013779464.1|2536331_2536865_-|DUF2815-family-protein
MSTKVVTGKVRFSYANVWEPQSVNGSDPKYSVSLIIPKSDKKTIEKIKAAIEVAKQEGASKLGKKIPANLKTPLRDGDIDRPDDEAYADSYFVNANSFTKPGIVDKNVEPILDQTEFYSGCYGRASITFYAYNVNGNKGIACGLQNLQKLEDGGPLGGKSRPEDDFEPVEIEEDFLG
>NC_019954.2|WP_013779463.1|2534373_2536332_-|DNA-polymerase
MTILSIDIETYSSVDLTKCGVYAYTQAEDFEILLFGYAFNNDPVEVIDLASGEQIPDEVTNAITDSAVIKTAFNANFERTCLAKYLNKPMPPEEWRCSQAHALTLGLPLNLAGVAKCLGLADQKMSEGKALIRYFSIPCKPTKANGGRTRNLPHHDREKWETFKAYCKQDVVVERSIRKRLENYPMTDKELKLWSLDQKINDYGVRVDRQLVENAICCDGIHQKELMAEAIDLTGLENPNSPAQLKTWLKGNHNIQVDSLSKANVEELLNKINHPTVTRVLELRQDMSKTSVRKYEAMDRAMGGDGRIRGLLQYYGANRTGRWAGRLVQVQNLPRNNMKDLDLARKLLLAGDYESLELLFDSVPDVLSQLIRTAFVPSPGHRFIISDFSAIEARVIAWLAGEKWVVDTFKGHGKIYEMTASKMFGVPMELIVKGNPEYELRQKGKVAVLACGYQGSVGALKAMGALNMGLKEDELPAIVAAWRESNPNIVKLWWDVEDAAIRAVKDRTSITMQYGLKFYYKSGVLFIRLPSGRNLAYVKPRIELDTRFNKDKLTYEGIMLGNKWARIDTYGGKLTENIIQAIARDCLAESLLRLDKAGYKIAFHVHDEVVLDVPQGFGSLKEVEEIMSQDINWAKGLPLRAEGFETNYYMKD
>NC_019954.2|WP_013779462.1|2534163_2534358_-|hypothetical-protein
MFYVKAKINDAVEIAAEIHDDNVFCTCPGCGCEVEVDLAEVFSNSDSDLYGTAVYCTKCRLEGK
>NC_019954.2|WP_013779473.1|2541904_2544163_-|Ig-like-domain-containing-protein
MLRISKRLLSLLLALTLILSMTTVAFAKDYDLINKNTLTRNDFFDLTDDMDFFSDVLDNPGQYVIEVNGKYYEVEQVDAATQDGTGIDEAVVGLVPVDLDTDEELKVVSVSAINAKEVQIKFSKAVKKDTVITTGAPDTLKNITFTNIGSAPAITSTSAEAKLSEDGKTLTITASGTEYFDGQYAVLVPVAVTDLDGNPIEAYSAVVTLKDTVRPTISGPTYPDNNTVKFEFSEPMNLTSGTTLEGISTLKDKNGATVSITGLITLATDKKSFTLNMAGLTVDEEYKLTIVGAKDFAGNLISPNPVTVSFKKQVVDNVNPEVVSVEAVNDSKLVVTFSEPIKTTPTIFKLNIGSTGTPVAVTTSNATVSDDKTVVTVDLTTAGFTSLSGLKRVDITEFQDLSGNPATITDSAYNTLINFVPDTEAPVVKTVTVETISGTRYIVVEFDEDVTVTAAALTPVTYVVDGVQKTLTGGIAVAAVSGYDKDSDGNDESVKIDTENYDGSGAVMPNGEYTITLPANLVADAAGKKNAQTTINVTIGDIADTTKPAVLSGLAGINLPDNDTVTIQFTEEVTNATALNTANYTVEGEKVFVSAIFDGDKTKVKLTLRDGAIDVNGERSLEIKNIADNAGNVMDPVTYPVDFTENVKPQMLSAKIVDVDKILVTFSEGIKATSAIPANFTVKVNGVSDTVTGVTEEDGATAVADGDTKVLLTLTTGIANLSDVVTVEIADETIEDVNGNLNKGAKTVTATR
>NC_019954.2|WP_013779474.1|2544246_2547246_-|S-layer-homology-domain-containing-protein
MRKAKKLLVTLLVLTFVMSTFSVGFAATTTDTKDLPTEVVRAMALGYLKGDAQGNLNLENPITRAEALAIIIRVSGLETSAELMKGQTKFADVNPDPSLEWATGYINLGVGQGIINGYPDGTFRGNANVTYAEMAKMILYAMNYGVTVEGAPWPAGVMGKADDLGLFDKVSSAPDAPAIRGDVVKMIDNSLTIKHLEQTGYGDLKQYVEGDKTFLSKMDVDELEDVRVTEIARVNDKLDDDEIELTEYDKNGKKVDSNIYTLIADVNPEAIFGLKVDAWVNDDDEVFFVEVSTEDKDILLDAVDAEESDEDEIYLKEADKAYKWADSAVAYVNFEEKDLDEIPEDAYGKFVLDRGQVAFANLFDFDEVGVVTAVDGKVIEFININTDEDEVDLSDYDDVYIYNPDFTKADVKDIDEDSAIFFWEGDDDDVYIIVKNETVKGNVDSVKEDKIKVDGKEYKRGSFKGTKALITLDKGDNYEEWADLEAVEDFVDEDVMLVLDLRGRVLLVTGAAKATSGNLYGIVTYAKSGRYPTLTVFNKEGKEVDYVAESSKEFDELTDLKYNANTPQYAALKYKLTSDSEIAEERSVYAVIEGTDITSRKSYDSDVKASEVIFEGKLTKDTDKKTFKLNGESFYISSDTVIMKALNEDGELDPETISVDRFVSIGVSQYNEAVVFGEAGKDADLIVMLNKAFEGTEEDYFYGVVTDKPYKSGSSYYATINVFGEGEKDYKVNDAADFKKGVVVAFNLNSKDEAVLKTSKLYDDKILKKYDDGFVTIDGKVYKVDSAAVLYNKDKDGDLDKKIGRTKLKEYANKRIDFALDDGIVVAAVVYDGKDGSSDTKVTGEVTYINVDEELIEVDGKVLELDKRVRLVDADGKTIAIGPKDVAKQLKVGDILSKITEEDGVVTEMKLAKDDDDEPGVPEEELTAEATLGSLLGVKYAEITLSDSSRIDEVKNVKVNGVVRDYNIKGDIIRVNFGSEITDIKLILNDGSVIDVTIK
>NC_019954.2|WP_013779475.1|2550092_2551175_-|peptidoglycan-bridge-formation-glycyltransferase-FemA/FemB-family-protein
MEIKIINQDEKKFFNDFMAWGPKGHVLQSYEWGEVKLHTGWEPIRLLVMDEGKPKAGISILKRKLPIPGFNKCIFYAPRGPVADYTDKDTLRFLFTKIKSMAKQHGAILLKIDPDIKAPNDEVVKNLRSLGFNLIDSGKDFDGVQPKFVFRLDISKPLEEIAADFHHKTRYNIRLAKRKGVTVKVGRREDLKPFYDILEETCIRDEFLVRSFDYFETLWDELVENGLARLFMAEYEGRYIAGTLAFIFGDKAWYIYGASSNEDRNVMPNYALQWAMIEWAKQNNCTMYDFRGVSGDLSPDNPLYGLYRFKKGFNGEFTEFIGEFDMPLSPFFYYLWVQVIPAYRKIRKDVVNFFRRAKKR
>NC_019954.2|WP_013779476.1|2551305_2552562_-|methyl-accepting-chemotaxis-protein
MKGIRLRVVLITMLLVAFSLGGYIYCFHGEDFASTNNLLAAAAAVLVSGIISFLVTKGASRPLEAIEQSLSAIAKGDFTVKAKRIIGDDIGALADVYNDSLDKVRKILKNAKDTTADMLASAASIGKITHQSKEMSSNIETSIKNALNHITDRLKEMKDLIDGMSDMLSQMTGGVEQIAVSSSEAAATASDASQLAESGRTAMDQVTLQMGKIKESSNYTASVIKSLGESSETIGQIVETITGIADQTNLLALNAAIEAARAGEQGRGFAVVADEIRKLAEQSGDAAKQIGQLIGTVLNEVDKAVKAKDQGSANVENGIKAVKSAAETFEQILVAVGKVAEQMQEISAATEQMAASTESTSESFKKMTDISLDGSNQAQTIIDSIEKQQKLLDEIASSVLRLGEDADKLDKIMNVIKI
>NC_019954.2|WP_013779477.1|2552625_2554233_-|CTP-synthase
MSTKYIFVTGGVVSSLGKGITAASLGRLLKSRGLSVTMQKCDPYINVDPGTMSPYQHGEVYVTDDGAEADLDLGHYERFIDVSLTKNSDITTGEIYWTVINKERQGKYHGKTVQVIPHITNEIKERIIRVGEESKADVVITEIGGTVGDIEGLPFLEAIRQMKTDVGRDNVLYIHVTLVPYISTAGELKTKPTQHSVKELRSIGIQPDIIVCRSEYAIPKDLKEKIALFCNVEPECVIQNYDAETIYEVPLILKDEGLDEIVAKKLGVDGRKAQLAEWVEIVQRIKNPLKQVNIALVGKYVELHDAYLSVVEALCHGGAANDAKVNIKWVHSEELEQESEKLSSVFYDIDGIIVPGGFGERGIEGMIKTVEYARENKIPFFGIGIGMQCAIIEFARNVCGLKDAHSTEINPETPHAVIDFPPEEKALNVKGAMRLGSYPCRVAENTIAMAAYGKELISERHRHRYEFNNDYRKVVTNFGLVLSGISPDDKFVEIIELKEHPWFLGTQFHPEFKSRPNKPHPLFTNFIKAAVNLKN
>NC_019954.2|WP_013779478.1|2554432_2555071_-|MBL-fold-metallo-hydrolase
MKIRWFGHSCFLLESKDGTKIVTDPFDGSVGYKIPMVEADIVTVSHDHYDHNYVEGIQGDPEVVKSTGECAISGISIKGIPAFHDEAKGAKRGPNIIYTFEIDGIRVCHVGDLGHLLSKTQIEEIGDVDVIMIPVGGTFTLDADGAAALIEQLSPKITIPMHFRTPAVSMPIDPVDKFVEKMGDVEHLDSNTIEINPETLDNQNRIVVLNYE
>NC_019954.2|WP_013779479.1|2555224_2556934_-|arginine--tRNA-ligase
MKDLKTQVQQKLMDIVMSALNKAIDDGALPIKDIPDFHIEVPQDKGHGDFATNIAMILAREAKMPPRKIGEVIAERVDTTHSNLIEKIEVAGPGFINFYLVPTWVNAVISDILKYGSDFGRCNTGEGKKVQVEFVSANPTGPMHMGNARGAALGDALASILEMVGFDVTKEFYINDAGNQIENFGLSLEARYLELMGKQGEIPEGGYHGEDIIEHMKDLIEQEGDRFLYMDSPTRRAYFINYALEKNIERMKKDLENFGVHFDVWFSEQSLHSSGKVNEVIKILTDRGYTYEKDGALWFKASQFGETKDEVLIRANGLPTYFASDIAYHKNKFDRGFDWVINIWGADHHGHIARMKGALEALGYDPDKLTVIIMQLVRLYRNGEIARMSKRTGRAVTLADIVEEVGKDAARFFFNLRSADTHLDFDLDLAIKQSDDNPVYYVQYAHARISSILRQAKEQGVDIPNVNNLTQNDMNKYADLLIEESEIELIKKLADFPGEIKLAADNLAPYRITVYSQELASAFHSFYNKCRVLTDAQDLTTARLLLVMAVQQVIKNALAILGISAPDRM
>NC_019954.2|WP_013779480.1|2557023_2557374_-|hypothetical-protein
MDLGWLKMIINVITNEAVMEPLIALILGYGVNIYAKNRRFKIIMDITADIVDYIEENYKDWGITGNEKMDKFLELFIKEFKKQVGRKPKDVEIETARIRAEALVQRARRDGGGKKR
>NC_019954.2|WP_015295929.1|2557393_2558002_-|orotate-phosphoribosyltransferase
MTDEDILKLFYETGVLKTGHFLLTSGRHSDKYMQCAQLLQYPKSTEQVCAKLAENVKDLGIQTVIGPAMGGIIISYEMGRQLNTRAIFTEREEGKMALRRGFTVKPGERILVVEDVVTTGGSVKEVISLIKELGGEVAAVAALVDRSGGKVDFGVPAHYLLKLQVESYAPEECPLCKKKLTYNKTRQSKKIISALIPPSRII
>NC_019954.2|WP_013779482.1|2558040_2558736_-|orotidine-5'-phosphate-decarboxylase
MSYDYSKVIIALDTPDEQKALEIVRLLKDKVSVFKVGLELFCSQGPKIVKKINNEGCKVFLDLKLHDIPNTVAGAAKACLSTGAFMLDVHASGGCQMMRKAREAVDNADVSPKPILLAITVLTSLDESDLAAVNINKSPTEQVKTLALMAKESGLDGVVASPKEISVIREAAGDDFLIVTPGVRPAWAATGDQKRVMTPAQALDEGADYIVVGRPVTAAPDPAEALNKLFQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019954_2	2.8\|131774\|35\|NC_019954\|PILER-CR,CRISPRCasFinder,CRT	131774-131808	35	MK448998	Streptococcus phage Javan636, complete genome	7076-7110	7	0.8
NC_019954_4	4.6\|147915\|36\|NC_019954\|PILER-CR,CRISPRCasFinder,CRT	147915-147950	36	LR694610	Escherichia phage rV5_ev168 genome assembly, chromosome: 1	109903-109938	7	0.806
NC_019954_4	4.6\|147915\|36\|NC_019954\|PILER-CR,CRISPRCasFinder,CRT	147915-147950	36	LR694611	Escherichia phage rV5_ev158 genome assembly, chromosome: 1	109955-109990	7	0.806
NC_019954_2	2.8\|131774\|35\|NC_019954\|PILER-CR,CRISPRCasFinder,CRT	131774-131808	35	NZ_CP018741	Bacillus cereus strain FORC_047 plasmid pFORC47_1, complete sequence	152926-152960	9	0.743
NC_019954_2	2.8\|131774\|35\|NC_019954\|PILER-CR,CRISPRCasFinder,CRT	131774-131808	35	NZ_CP018741	Bacillus cereus strain FORC_047 plasmid pFORC47_1, complete sequence	159466-159500	9	0.743
NC_019954_2	2.8\|131774\|35\|NC_019954\|PILER-CR,CRISPRCasFinder,CRT	131774-131808	35	HM452126	Aeromonas phage phiAS5, complete genome	5323-5357	9	0.743
NC_019954_2	2.8\|131774\|35\|NC_019954\|PILER-CR,CRISPRCasFinder,CRT	131774-131808	35	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	55477-55511	10	0.714
NC_019954_2	2.17\|132376\|36\|NC_019954\|PILER-CR,CRISPRCasFinder,CRT	132376-132411	36	MN694515	Marine virus AFVG_250M511, complete genome	10209-10244	11	0.694

1. spacer 2.8|131774|35|NC_019954|PILER-CR,CRISPRCasFinder,CRT matches to MK448998 (Streptococcus phage Javan636, complete genome) position: , mismatch: 7, identity: 0.8

attgcttcttcaacacctttttcaattccagtgtg	CRISPR spacer
attgcttcttcaacacctttttcaaatgcttcgaa	Protospacer
************************* * *  .* .

2. spacer 4.6|147915|36|NC_019954|PILER-CR,CRISPRCasFinder,CRT matches to LR694610 (Escherichia phage rV5_ev168 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.806

aaatatgaatttatagataaaatggagcaacaaggc	CRISPR spacer
aaactgtaatatataaataaaatggagcaacaagcc	Protospacer
***.   *** ****.****************** *

3. spacer 4.6|147915|36|NC_019954|PILER-CR,CRISPRCasFinder,CRT matches to LR694611 (Escherichia phage rV5_ev158 genome assembly, chromosome: 1) position: , mismatch: 7, identity: 0.806

aaatatgaatttatagataaaatggagcaacaaggc	CRISPR spacer
aaactgtaatatataaataaaatggagcaacaagcc	Protospacer
***.   *** ****.****************** *

4. spacer 2.8|131774|35|NC_019954|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018741 (Bacillus cereus strain FORC_047 plasmid pFORC47_1, complete sequence) position: , mismatch: 9, identity: 0.743

attgcttcttcaacacctttttcaattccagtgtg	CRISPR spacer
ttgccttcttcaatacctttttcaatacctttttt	Protospacer
 *  *********.************ **  * *

5. spacer 2.8|131774|35|NC_019954|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018741 (Bacillus cereus strain FORC_047 plasmid pFORC47_1, complete sequence) position: , mismatch: 9, identity: 0.743

attgcttcttcaacacctttttcaattccagtgtg	CRISPR spacer
ttgccttcttcaatacctttttcaatacctttttt	Protospacer
 *  *********.************ **  * *

6. spacer 2.8|131774|35|NC_019954|PILER-CR,CRISPRCasFinder,CRT matches to HM452126 (Aeromonas phage phiAS5, complete genome) position: , mismatch: 9, identity: 0.743

attgcttcttcaacacctttttcaattccagtgtg	CRISPR spacer
tttgctacttcaacacgtttttcaatagcatcgac	Protospacer
 ***** ********* *********  ** .*

7. spacer 2.8|131774|35|NC_019954|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 10, identity: 0.714

attgcttcttcaacacctttttcaattccagtgtg	CRISPR spacer
attgcatcttcaacacatttttcaatgttttcatt	Protospacer
***** ********** ********* ..  ..*

8. spacer 2.17|132376|36|NC_019954|PILER-CR,CRISPRCasFinder,CRT matches to MN694515 (Marine virus AFVG_250M511, complete genome) position: , mismatch: 11, identity: 0.694

tttggtatgattttcagggtgttggtggtagaacag	CRISPR spacer
attggtctgattttgagggtgttggtgtaggcttta	Protospacer
 ***** ******* ************  .*  . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

937832 : 990453

Erysipelothrix_phage(18.18%)

tRNA,transposase,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015295119.1\|937832_938315_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_013777964.1\|938383_940432_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	5.3e-14	36.0
WP_013777965.1\|940792_940939_+	TRAM domain-containing protein	NA	NA	NA	NA
WP_013777966.1\|941086_942796_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_013777967.1\|942951_944334_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	3.4e-105	42.2
WP_013777968.1\|944811_945117_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_013777969.1\|945113_945848_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.2e-23	35.4
WP_013777970.1\|945844_946582_+	ABC transporter permease	NA	NA	NA	NA
WP_013777971.1\|946705_947503_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_013777972.1\|947590_948670_+	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_013777973.1\|948837_949116_+	hypothetical protein	NA	NA	NA	NA
WP_013777974.1\|949294_950062_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_013777975.1\|950498_950894_+	HEPN domain-containing protein	NA	NA	NA	NA
WP_013777976.1\|950863_951184_+	nucleotidyltransferase domain-containing protein	NA	NA	NA	NA
WP_013777978.1\|952266_953514_+	nucleotidyltransferase	NA	NA	NA	NA
WP_013777979.1\|953517_954174_+	SEC-C domain-containing protein	NA	NA	NA	NA
WP_013777980.1\|954188_955310_+	SAVED domain-containing protein	Q858S3	Enterobacteria_phage	1.0e-06	31.4
WP_013777982.1\|956475_956757_+\|transposase	transposase	NA	NA	NA	NA
WP_013777983.1\|957763_960769_+	DEAD/DEAH box helicase family protein	U6E9C9	Streptococcus_phage	4.7e-11	23.1
WP_013777984.1\|961176_962313_+	Abi family protein	NA	NA	NA	NA
WP_013777985.1\|962345_963101_-	ABC transporter permease	NA	NA	NA	NA
WP_013777986.1\|963075_964050_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	9.8e-27	26.8
WP_013777987.1\|964052_964508_-	GyrI-like domain-containing protein	NA	NA	NA	NA
WP_013777988.1\|964511_965375_-	AraC family transcriptional regulator	D0R0F8	Streptococcus_phage	4.5e-23	29.0
WP_015295135.1\|965635_966148_+\|transposase	transposase	NA	NA	NA	NA
WP_048894704.1\|966249_967011_+\|transposase	transposase	NA	NA	NA	NA
WP_048894705.1\|967109_967391_-	hypothetical protein	NA	NA	NA	NA
WP_015295138.1\|967342_968485_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_144312818.1\|968445_968592_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
WP_013777991.1\|970603_971251_+	hypothetical protein	NA	NA	NA	NA
WP_013777992.1\|971254_971566_+	hypothetical protein	NA	NA	NA	NA
WP_013777993.1\|971770_972568_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_013777994.1\|972760_973435_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.6e-34	36.4
WP_013777995.1\|973422_974607_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_013777996.1\|974666_975542_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-19	28.9
WP_013777997.1\|975544_976624_+	ABC transporter permease	NA	NA	NA	NA
WP_013777998.1\|976620_977292_+	hypothetical protein	NA	NA	NA	NA
WP_013777999.1\|978190_979687_+	ABC-F type ribosomal protection protein Lsa(E)	A0A2H4UUX5	Bodo_saltans_virus	1.7e-25	26.8
WP_013778000.1\|979680_980175_+	nucleotidyltransferase family protein	A0A2K5B286	Erysipelothrix_phage	7.8e-81	84.8
WP_015295145.1\|980649_981183_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_013778002.1\|981363_981915_+	hypothetical protein	NA	NA	NA	NA
WP_013778003.1\|982023_982197_+	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_015295146.1\|982481_983249_+	hypothetical protein	NA	NA	NA	NA
WP_013778004.1\|983567_984152_-	accessory gene regulator B family protein	NA	NA	NA	NA
WP_023211414.1\|984171_984636_-	sensor histidine kinase	NA	NA	NA	NA
WP_015295148.1\|984632_985451_-	hypothetical protein	NA	NA	NA	NA
WP_013778005.1\|985466_986171_-	response regulator transcription factor	NA	NA	NA	NA
WP_013778006.1\|986440_986584_+	cyclic lactone autoinducer peptide	NA	NA	NA	NA
WP_013778007.1\|986643_987300_+	hypothetical protein	NA	NA	NA	NA
WP_013778008.1\|987617_988004_+	hypothetical protein	NA	NA	NA	NA
WP_013778009.1\|988070_988202_+	cyclic lactone autoinducer peptide	NA	NA	NA	NA
WP_013778010.1\|988317_989136_+	hypothetical protein	NA	NA	NA	NA
WP_013778011.1\|989201_989426_-	hypothetical protein	NA	NA	NA	NA
WP_013778012.1\|989502_990453_+\|transposase	IS256 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

1081288 : 1111233

Paenibacillus_phage(10.71%)

capsid,head,integrase,tail,portal,transposase,terminase

attL 1084543:1084602|attR 1111324:1111410

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013778088.1\|1081288_1081993_-	N-acetylmuramoyl-L-alanine amidase	A0A0N9SGH1	Paenibacillus_phage	6.1e-10	31.0
WP_015295215.1\|1082305_1084426_+	ribonuclease R	Q0GXV6	Lactococcus_phage	1.4e-73	38.0
1084543:1084602	attL	NA	NA	NA	NA
WP_013778090.1\|1084694_1085093_-	ImmA/IrrE family metallo-endopeptidase	Q0H245	Geobacillus_phage	9.3e-16	43.8
WP_144312819.1\|1085409_1086294_-	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	3.1e-56	43.4
WP_013778092.1\|1086441_1086837_-	helix-turn-helix transcriptional regulator	A0A139ZPJ2	Marinitoga_camini_virus	3.1e-11	34.3
WP_013778093.1\|1087021_1087279_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013778094.1\|1087379_1087586_+	hypothetical protein	NA	NA	NA	NA
WP_013778095.1\|1087577_1087751_-	hypothetical protein	A0A090DBW4	Clostridium_phage	8.4e-06	44.6
WP_013778096.1\|1087850_1088084_+	hypothetical protein	NA	NA	NA	NA
WP_013778097.1\|1088076_1088232_+	hypothetical protein	NA	NA	NA	NA
WP_013778098.1\|1088297_1088954_+	ERF family protein	A0A0M3ULL1	Bacillus_phage	1.1e-32	40.2
WP_013778099.1\|1089030_1089390_+	hypothetical protein	NA	NA	NA	NA
WP_013778100.1\|1089390_1089768_+	hypothetical protein	NA	NA	NA	NA
WP_013778101.1\|1089867_1090668_+	phage replisome organizer N-terminal domain-containing protein	D2JGK4	Staphylococcus_phage	3.9e-37	60.8
WP_013778102.1\|1090664_1091963_+	AAA family ATPase	A0A097BYG3	Leuconostoc_phage	2.7e-40	31.0
WP_013778103.1\|1092007_1092232_+	hypothetical protein	NA	NA	NA	NA
WP_013778104.1\|1092269_1092455_+	hypothetical protein	NA	NA	NA	NA
WP_013778105.1\|1092484_1092658_+	hypothetical protein	NA	NA	NA	NA
WP_013778106.1\|1092657_1092903_+	DUF370 domain-containing protein	NA	NA	NA	NA
WP_013778107.1\|1092895_1093285_+	single-stranded DNA-binding protein	A0A0K2CYR2	Paenibacillus_phage	6.7e-35	64.0
WP_154646181.1\|1093286_1093436_+	hypothetical protein	NA	NA	NA	NA
WP_013778109.1\|1093563_1093920_+	hypothetical protein	E5DV93	Deep-sea_thermophilic_phage	1.2e-09	42.1
WP_013778110.1\|1094026_1094215_+	hypothetical protein	NA	NA	NA	NA
WP_013778111.1\|1094211_1094391_+	hypothetical protein	NA	NA	NA	NA
WP_013778113.1\|1095101_1095506_-	type II toxin-antitoxin system HicB family antitoxin	A0A0C5AN56	Paenibacillus_phage	2.2e-25	47.8
WP_013778114.1\|1095542_1095722_-	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_013778115.1\|1095910_1096240_+	hypothetical protein	NA	NA	NA	NA
WP_013778116.1\|1096314_1097037_+	hypothetical protein	A0A0A8WFS6	Clostridium_phage	5.7e-56	53.9
WP_013778117.1\|1097026_1098280_+\|terminase	PBSX family phage terminase large subunit	S6AVV7	Thermus_phage	4.9e-103	47.4
WP_013778118.1\|1098293_1099736_+\|portal	phage portal protein	A0A0A7S074	Clostridium_phage	1.5e-116	47.2
WP_013778119.1\|1099767_1101309_+\|capsid	minor capsid protein	A0A1X9I626	Streptococcus_phage	1.8e-70	33.0
WP_013778120.1\|1101295_1101508_+	hypothetical protein	NA	NA	NA	NA
WP_013778121.1\|1101571_1102306_+	hypothetical protein	Q9AYX4	Lactococcus_phage	5.7e-19	30.7
WP_013778122.1\|1102433_1102721_+	hypothetical protein	A0A1J1JCG1	Escherichia_phage	1.8e-13	45.4
WP_013778123.1\|1102832_1103399_+	phage scaffolding protein	S5MUG0	Brevibacillus_phage	9.1e-25	42.0
WP_013778124.1\|1103418_1104363_+	hypothetical protein	A0A1V0DZW0	Clostridioides_phage	5.5e-91	56.9
WP_013778126.1\|1104537_1104840_+\|head,tail	phage head-tail connector protein	A0A2H4JD74	uncultured_Caudovirales_phage	4.3e-05	35.8
WP_013778127.1\|1104844_1105177_+	hypothetical protein	A0A2H4J6Q5	uncultured_Caudovirales_phage	5.2e-12	37.6
WP_013778128.1\|1105173_1105701_+	HK97 gp10 family phage protein	A0A059NT55	Lactococcus_phage	6.1e-23	36.0
WP_013778129.1\|1105700_1106054_+	hypothetical protein	M1NSH7	Streptococcus_phage	7.4e-17	39.5
WP_013778130.1\|1106071_1106497_+\|tail	tail protein	Q6SE73	Lactobacillus_prophage	4.2e-06	31.2
WP_013778131.1\|1106916_1107405_+	hypothetical protein	A0A290GDU0	Caldibacillus_phage	9.9e-20	45.8
WP_173391429.1\|1107432_1108341_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	8.6e-33	34.5
WP_013778132.1\|1108349_1108634_-\|transposase	transposase	NA	NA	NA	NA
WP_144312820.1\|1108727_1108901_+	hypothetical protein	NA	NA	NA	NA
WP_013778133.1\|1108932_1109826_+	hypothetical protein	NA	NA	NA	NA
WP_013778134.1\|1110339_1111233_-\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	4.1e-19	31.9
1111324:1111410	attR	NA	NA	NA	NA

DBSCAN-SWA_3

2466860 : 2556934

Erysipelothrix_phage(20.93%)

capsid,head,integrase,protease,holin,tail,bacteriocin,portal,tRNA,transposase,terminase

attL 2494794:2494817|attR 2527294:2527317

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013779391.1\|2466860_2467649_-\|bacteriocin	bacteriocin family protein	NA	NA	NA	NA
WP_013779392.1\|2467665_2468007_-	hypothetical protein	NA	NA	NA	NA
WP_081697910.1\|2468528_2468687_-	hypothetical protein	NA	NA	NA	NA
WP_015295890.1\|2468662_2468986_-	RNA polymerase sigma factor SigV	NA	NA	NA	NA
WP_015295892.1\|2469797_2470763_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013779395.1\|2470796_2471645_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_013779396.1\|2471669_2472848_+	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.2e-28	33.6
WP_013779397.1\|2473265_2474564_-	hypothetical protein	NA	NA	NA	NA
WP_013779398.1\|2474886_2475483_+	DUF3298 and DUF4163 domain-containing protein	NA	NA	NA	NA
WP_013779399.1\|2475878_2477216_-	amino acid permease	NA	NA	NA	NA
WP_013779400.1\|2477299_2478490_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_013779401.1\|2478601_2478802_-	helix-turn-helix transcriptional regulator	B5LPU7	Bacillus_virus	6.3e-05	41.7
WP_013779402.1\|2478997_2479309_+	helix-turn-helix transcriptional regulator	S5MTZ5	Brevibacillus_phage	9.8e-13	40.7
WP_023211625.1\|2479906_2481217_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	9.9e-06	68.3
WP_023211628.1\|2482777_2483359_-	PDC sensor domain-containing protein	NA	NA	NA	NA
WP_081460128.1\|2483969_2485739_-	M56 family metallopeptidase	NA	NA	NA	NA
WP_015295905.1\|2485741_2486299_-	Regulatory sensor-transducer, BlaR1/MecR1 family	NA	NA	NA	NA
WP_015295906.1\|2486327_2486717_-	BlaI/MecI/CopY family transcriptional regulator	NA	NA	NA	NA
WP_013779405.1\|2487676_2487904_-	hypothetical protein	NA	NA	NA	NA
WP_013779407.1\|2488024_2488300_-	hypothetical protein	NA	NA	NA	NA
WP_015295909.1\|2488402_2488711_-\|head,tail	phage gp6-like head-tail connector protein	M1PSE8	Streptococcus_phage	2.9e-09	45.8
WP_013779409.1\|2489224_2489557_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_013779410.1\|2489546_2489858_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_013779411.1\|2490526_2492104_+	copper amine oxidase N-terminal domain-containing protein	NA	NA	NA	NA
WP_023211631.1\|2492372_2492621_-	hypothetical protein	NA	NA	NA	NA
WP_013779412.1\|2493361_2493730_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_013779413.1\|2493732_2494023_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_013779414.1\|2494286_2494565_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_013779415.1\|2494657_2495038_-	HNH endonuclease	M1PLL8	Streptococcus_phage	6.1e-25	46.1
2494794:2494817	attL	NA	NA	NA	NA
WP_048894750.1\|2495619_2497338_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_013779416.1\|2497844_2498402_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_013779417.1\|2498566_2498749_-	hypothetical protein	NA	NA	NA	NA
WP_023211634.1\|2498860_2499124_-	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_013779418.1\|2499234_2499465_-	type II toxin-antitoxin system MqsA family antitoxin	NA	NA	NA	NA
WP_013779419.1\|2499470_2499785_-	DUF4258 domain-containing protein	NA	NA	NA	NA
WP_013779420.1\|2500102_2501971_-	Ig-like domain-containing protein	NA	NA	NA	NA
WP_013779421.1\|2502332_2503385_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_013779422.1\|2503461_2504205_-	hypothetical protein	NA	NA	NA	NA
WP_013779423.1\|2504216_2505074_-\|integrase	tyrosine-type recombinase/integrase	S5M9V8	Brevibacillus_phage	5.8e-15	25.0
WP_013779424.1\|2505213_2505876_-	N-acetylmuramoyl-L-alanine amidase	A0A0N9SGH1	Paenibacillus_phage	3.0e-27	43.0
WP_013779425.1\|2505868_2506279_-\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	5.2e-38	58.5
WP_013779426.1\|2506312_2507410_-	siphovirus ReqiPepy6 Gp37-like family protein	A0A0K2CZQ1	Paenibacillus_phage	4.1e-82	42.6
WP_013779427.1\|2507426_2507558_-	XkdX family protein	NA	NA	NA	NA
WP_013779428.1\|2507559_2507937_-	hypothetical protein	NA	NA	NA	NA
WP_013779429.1\|2507951_2509028_-	hypothetical protein	NA	NA	NA	NA
WP_013779430.1\|2509027_2509975_-	hypothetical protein	A0A2I7SC02	Paenibacillus_phage	4.1e-62	56.3
WP_013779431.1\|2509989_2510841_-\|tail	phage tail family protein	A0A0K2CZA8	Paenibacillus_phage	1.8e-64	45.7
WP_013779432.1\|2510851_2513164_-\|tail	phage tail tape measure protein	A0A1J0MFP9	Staphylococcus_phage	1.3e-40	53.6
WP_013779433.1\|2513344_2514304_-	DUF2726 domain-containing protein	Q4Z8X8	Staphylococcus_phage	1.8e-49	35.4
WP_013779434.1\|2514382_2515399_-\|tail	phage tail tape measure protein	A0A2H4J669	uncultured_Caudovirales_phage	2.0e-54	46.1
WP_013779435.1\|2515446_2515602_-	hypothetical protein	NA	NA	NA	NA
WP_013779436.1\|2515613_2515913_-	hypothetical protein	H0USX2	Bacillus_phage	6.3e-09	32.6
WP_013779437.1\|2515930_2516503_-\|tail	tail protein	E2ELJ1	Clostridium_phage	6.4e-34	44.6
WP_013779438.1\|2516504_2516831_-	hypothetical protein	A0A2I7SC10	Paenibacillus_phage	1.4e-17	39.8
WP_013779439.1\|2516827_2517199_-	HK97 gp10 family phage protein	H0USW9	Bacillus_phage	4.7e-14	40.8
WP_013779440.1\|2517191_2517518_-\|head	phage head closure protein	A0A0A7RUH8	Clostridium_phage	2.9e-23	52.8
WP_013779441.1\|2517514_2517802_-\|head,tail	phage gp6-like head-tail connector protein	A6M953	Geobacillus_virus	1.0e-24	56.7
WP_013779442.1\|2517845_2519027_-\|capsid	phage major capsid protein	A0A2I7SBY4	Paenibacillus_phage	2.5e-101	57.2
WP_013779443.1\|2519062_2519752_-\|protease	Clp protease ClpP	A0A0K2CYC6	Paenibacillus_phage	1.9e-56	51.4
WP_013779444.1\|2519741_2520998_-\|portal	phage portal protein	Q2I8F9	Bacillus_phage	4.0e-137	55.6
WP_013779445.1\|2521009_2522575_-\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	1.2e-228	74.4
WP_013779446.1\|2522574_2523048_-\|terminase	phage terminase small subunit P27 family	Q6DMU4	Streptococcus_phage	8.1e-59	72.7
WP_013779447.1\|2523087_2523381_-	hypothetical protein	NA	NA	NA	NA
WP_015295921.1\|2523598_2523787_-	hypothetical protein	A0A127AWS3	Bacillus_phage	1.6e-10	60.7
WP_013779448.1\|2523779_2524541_-	hypothetical protein	A0A2K5B280	Erysipelothrix_phage	1.9e-17	32.3
WP_013779449.1\|2524627_2524927_-	hypothetical protein	A0A2K5B282	Erysipelothrix_phage	3.3e-26	59.4
WP_041591602.1\|2525036_2526269_-	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	2.8e-143	60.6
WP_013779451.1\|2526571_2526850_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_013779452.1\|2526846_2527122_+	type II toxin-antitoxin system YafQ family toxin	NA	NA	NA	NA
WP_013779453.1\|2527151_2527538_-	HNH endonuclease	Q38456	Bacillus_phage	1.6e-25	51.7
2527294:2527317	attR	NA	NA	NA	NA
WP_013779454.1\|2527500_2527737_-	hypothetical protein	NA	NA	NA	NA
WP_013779455.1\|2527982_2528414_-	DUF1492 domain-containing protein	NA	NA	NA	NA
WP_013779456.1\|2528403_2528619_-	hypothetical protein	NA	NA	NA	NA
WP_013779457.1\|2528621_2529977_-	DEAD/DEAH box helicase	S5MA26	Brevibacillus_phage	1.7e-162	60.8
WP_013779458.1\|2529973_2530252_-	VRR-NUC domain-containing protein	A0A2K5B272	Erysipelothrix_phage	2.5e-23	61.1
WP_013779459.1\|2530536_2532942_-	virulence-associated E family protein	A0A1S7FZ15	Listeria_phage	1.7e-237	51.2
WP_013779460.1\|2532925_2533480_-	DUF3310 domain-containing protein	A0A2K9V2W4	Faecalibacterium_phage	1.9e-22	52.5
WP_013779461.1\|2533495_2534164_-	Rha family transcriptional regulator	A0A2K5B268	Erysipelothrix_phage	8.1e-89	71.4
WP_013779462.1\|2534163_2534358_-	hypothetical protein	A0A2K5B269	Erysipelothrix_phage	3.8e-15	59.3
WP_013779463.1\|2534373_2536332_-	DNA polymerase	S5M5X4	Brevibacillus_phage	1.6e-238	63.3
WP_013779464.1\|2536331_2536865_-	DUF2815 family protein	A0A0A7RVM4	Clostridium_phage	2.1e-63	67.0
WP_013779466.1\|2538024_2538306_-	hypothetical protein	A0A2K5B2A7	Erysipelothrix_phage	4.4e-12	46.1
WP_013779467.1\|2538320_2538572_-	hypothetical protein	NA	NA	NA	NA
WP_013779468.1\|2538590_2538914_-	HTH domain-containing protein	NA	NA	NA	NA
WP_013779469.1\|2539367_2540090_-	ImmA/IrrE family metallo-endopeptidase	E4ZFJ9	Streptococcus_phage	7.3e-27	35.3
WP_013779470.1\|2540104_2540473_-	hypothetical protein	NA	NA	NA	NA
WP_013779471.1\|2540476_2540863_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013779472.1\|2540877_2541669_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_013779473.1\|2541904_2544163_-	Ig-like domain-containing protein	NA	NA	NA	NA
WP_013779474.1\|2544246_2547246_-	S-layer homology domain-containing protein	NA	NA	NA	NA
WP_013779475.1\|2550092_2551175_-	peptidoglycan bridge formation glycyltransferase FemA/FemB family protein	NA	NA	NA	NA
WP_013779476.1\|2551305_2552562_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.0e-12	43.1
WP_013779477.1\|2552625_2554233_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	8.3e-156	52.4
WP_013779478.1\|2554432_2555071_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_013779479.1\|2555224_2556934_-\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_019954

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection