CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NC_018689	Bacillus thuringiensis MC28 plasmid pMC429, complete sequence	1 crisprs	cas14j,csa3	0	1	3
NC_018688	Bacillus thuringiensis MC28 plasmid pMC319, complete sequence	0 crisprs	RT,cas14j,csa3,cas7,cas8c,cas5	0	0	1
NC_018693	Bacillus thuringiensis MC28, complete sequence	2 crisprs	DinG,csa3,cas3,c2c9_V-U4,WYL,DEDDh	0	28	7
NC_018684	Bacillus thuringiensis MC28 plasmid pMC8, complete sequence	0 crisprs	NA	0	0	0
NC_018685	Bacillus thuringiensis MC28 plasmid pMC95, complete sequence	0 crisprs	csa3	0	0	1
NC_018687	Bacillus thuringiensis MC28 plasmid pMC189, complete sequence	2 crisprs	RT,csa3	0	2	1
NC_018694	Bacillus thuringiensis MC28 plasmid pMC54, complete sequence	0 crisprs	NA	0	0	1
NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	1 crisprs	RT	4	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_018689_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018689_1

300023-300113

Orphan

Consensus_repeat	Method
TAAAAGATAAAGAAGAGGATGTAAAAGC	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_018689_1

>merge|NC_018689|1|300023-300113|CRISPRCasFinder
TAAAAGATAAAGAAGAGGATGTAAAAGCGGATGTTAAACCAGTAGCGCAATCAAATGAGGAACTAAAAGATAAAGAAGAAGATGTAAAAGC

>NC_018689|1|1|300023-300113|CRISPRCasFinder
TAAAAGATAAAGAAGAGGATGTAAAAGC	GGATGTTAAACCAGTAGCGCAATCAAATGAGGAAC
TAAAAGATAAAGAAGAAGATGTAAAAGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018689.1\|WP_000920897.1\|297793_298276_+\|hypothetical-protein	unknown	unknown	unknown
NC_018689.1\|WP_000192361.1\|294787_295192_+\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372239
NC_018689.1\|WP_000428112.1\|305872_306175_-\|hypothetical-protein	unknown	unknown	unknown
NC_018689.1\|WP_001277524.1\|311494_311791_+\|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|223713
NC_018689.1\|WP_000421392.1\|294455_294746_+\|hypothetical-protein	unknown	unknown	unknown
NC_018689.1\|WP_001118180.1\|290637_292347_+\|hypothetical-protein	unknown	unknown	unknown
NC_018689.1\|WP_000724398.1\|305023_305620_+\|hypothetical-protein	unknown	unknown	unknown
NC_018689.1\|WP_000377606.1\|307591_308461_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234623
NC_018689.1\|WP_000693609.1\|313317_313596_+\|hypothetical-protein	unknown	unknown	unknown
NC_018689.1\|WP_000239383.1\|293346_294453_+\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372237
NC_018689.1\|WP_014990771.1\|304309_304972_+\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|366353
NC_018689.1\|WP_000100536.1\|283724_285260_+\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NC_018689.1\|WP_000312828.1\|306241_306616_-\|hypothetical-protein	unknown	unknown	unknown
NC_018689.1\|WP_079995239.1\|310661_310763_-\|YjcZ-family-sporulation-protein	unknown	unknown	unknown
NC_018689.1\|WP_001130026.1\|283000_283732_+\|gluconate-operon-transcriptional-repressor-GntR	unknown	unknown	gnl\|CDD\|224715
NC_018689.1\|WP_001216134.1\|314198_314384_+\|hypothetical-protein	unknown	unknown	unknown
NC_018689.1\|WP_001275775.1\|308460_309432_+\|hypothetical-protein	unknown	unknown	unknown
NC_018689.1\|WP_000413552.1\|286987_288397_+\|NADP-dependent-phosphogluconate-dehydrogenase	unknown	unknown	gnl\|CDD\|236453
NC_018689.1\|WP_001077398.1\|295251_297792_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|315512
NC_018689.1\|WP_001131717.1\|285376_286723_+\|gluconate-permease-GntP	unknown	unknown	gnl\|CDD\|129873

Protein	Function_ID	Function_description	E-value
NC_018689.1\|WP_000377606.1\|307591_308461_+\|hypothetical-protein	gnl\|CDD\|234623	PRK00087, PRK00087, bifunctional 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/30S ribosomal protein S1.	2.63209e-12
NC_018689.1\|WP_000192361.1\|294787_295192_+\|conjugal-transfer-protein	gnl\|CDD\|372239	pfam12648, TcpE, TcpE family. This family of proteins includes TcpE a conjugative transposon membrane protein.This family of proteins is found in bacteria. Proteins in this family are typically between 122 and 168 amino acids in length.	1.98752e-16
NC_018689.1\|WP_014990771.1\|304309_304972_+\|C40-family-peptidase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	1.29636e-25
NC_018689.1\|WP_000100536.1\|283724_285260_+\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NC_018689.1\|WP_001077398.1\|295251_297792_+\|ATP-binding-protein	gnl\|CDD\|315512	pfam12846, AAA_10, AAA-like domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins.	2.4432e-105
NC_018689.1\|WP_001277524.1\|311494_311791_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|223713	COG0640, ArsR, Predicted transcriptional regulators [Transcription].	5.55009e-10
NC_018689.1\|WP_001130026.1\|283000_283732_+\|gluconate-operon-transcriptional-repressor-GntR	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	2.5071e-44
NC_018689.1\|WP_000413552.1\|286987_288397_+\|NADP-dependent-phosphogluconate-dehydrogenase	gnl\|CDD\|236453	PRK09287, PRK09287, NADP-dependent phosphogluconate dehydrogenase.	0
NC_018689.1\|WP_000239383.1\|293346_294453_+\|conjugal-transfer-protein	gnl\|CDD\|372237	pfam12642, TpcC, Conjugative transposon protein TcpC. This family of proteins are annotated as conjugative transposon protein TcpC. The transfer clostridial plasmid (tcp) locus is part of some conjugative antibiotic resistance and virulence plasmids. TcpC was one of five genes whose products had low-level sequence identity to Tn916 proteins, having similarity to ORF13 homologs from Tn916, Tn5397, and CW459tet. This family of proteins is found in bacteria. Proteins in this family are typically between 302 and 351 amino acids in length.	6.20814e-25
NC_018689.1\|WP_001131717.1\|285376_286723_+\|gluconate-permease-GntP	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0

>NC_018689.1|WP_000920897.1|297793_298276_+|hypothetical-protein
MLKTKFKKIMLTSLCVGTLFLSAACGNSETNVGEEKDKQGHTPREMMLDFVKADLQHDHKTIRKLIVDGDKNTVLDPNRGPQNNLSYKDYTVKEYVVDKDTIMYNFISKKPPKNIDKAVKWVRVVRTEDGFKVRSYSSPYRNEIDEVANNKPTNEFSSKD
>NC_018689.1|WP_001077398.1|295251_297792_+|ATP-binding-protein
MNQVEFPVKYFHNNLIFNQDGSCWAYYEAYGIPYEFRGDDDKNTLFMRQLGLFWNFDEEKHLLMIPVYQNFQEKADEFKGTISGELKELAIYHTDDVVHELERKFGKNAVEYRYFIGVKLKVRHIQEGLKEMLYTAFHTFKNTAEQFGLLGDTKILKTDLEMFKREASAFKNKIRKHLAVRALETNETQWVILRNFYRTLEAPVTAGWTPPVQNDDSAIIPNQESLLRLSEAEFDVKGRHIEMSQIGTDGLEYPAYMSFLSASKIPYTMEFPDQEWMYMIQNIDFPIELSVRTENINHRKALSKLNKKKKDLEDQEAHARENAQTVGLNVYEGVQEATELQALIQKTRMPLVKTSVSFCICAEDLDTMRRNTNSLISIYREMMIELVRPYGDQFLLFNEFIPGSRRYVNDYIHFMEPGVLAAGMFGATQDLGDNIGFYIGTTGILNKAVYMTPSLAATNTVANQKTSALSVAVTGSTGSGKSFGTNLIVYLAVLGGAQTLIVDPKGERGNWTEDLHGLEGKVNVITLGTDRRDEGKLDPFIIHKHSRKDAIELAMTILTFITGIKPDNSEKFPRLASAVEFVAGMEEPCLTAVSQYLEDSEDKVDQQLAAHIQAFENLSFAHLIFGDGTNRDIELDTAVNIIQIQHLDMPDIQKDPKDYTLQENLSVSMLMSLSSFARKFFQKDPTKFKIVLLDEAWAIMGTSQGRELARKLVREGRALNSAVYFATQSASDLGDETFKNNIGMKFSFRNTDSKEISSILDFFGLPDNEENHAIITNLETGQCLFQDIQGRTGVVTMDVVFKDLYDAFDTRPNARKNYRKSNDDERQEVNATFVEEGGEKINVGVS
>NC_018689.1|WP_000192361.1|294787_295192_+|conjugal-transfer-protein
MTQKPTRKEVRTYNSIWDIPKSLYGIRDLTLPFPVPYRQLGFFVGSLFLILILDQFLPLGNNVFLKYLILPGGIAYFFGNVELDGKSPLKFLFRFFVFMFESKKISRYKDTTGNIGSYQYKTLIRFKDDSINNK
>NC_018689.1|WP_000421392.1|294455_294746_+|hypothetical-protein
MELLGLDMVAQQLPAITDAAVIGNINFGVNIKNWLVAQLGPIFLVVALIGVIVFAVKRQMAGLLGWIIVCALLSVFVFSPDIFKDLGTKLYNLVFK
>NC_018689.1|WP_000239383.1|293346_294453_+|conjugal-transfer-protein
MVKKKSQKNAEKKKFTFFKKAKNKTTELLDMQQENSEALKEKKTRKTREKVPVITGRKVGKVTFWCVMGFVFAGSSLSFIQLAGPPRAVAVQEKKEEPVKVKMSEAELIVYANSFAADYFNWKVDMNVAETRKKRLEKYLVEGSDEQGGLNRDSLKNASSTLVKSEAVEVRQKGNEAEVTLKIIQKLEPINNPAPGTTQAPDTPKEPKEVTRYFSIPILMEKGKMVIPDHPTIVHGEREKASYKVATFKSEGREINTDSEIKKVEQFLQSVFKVYTEGTPEEIAYYFEKSNITNGLKGIMTFSKLENLRIYEDKDKGYRVLVDAKLKDNDSSLEYTYTYDLNLVNKDNKFSINSMKKFENTLEKVEDK
>NC_018689.1|WP_001118180.1|290637_292347_+|hypothetical-protein
MAKPFVIKNKRSLNGETTTPVIVTIKSWQKLVEALEGKYYSFKDTYLEDIVNSMSYEERIADEEGFVEQAKPSFSLKMKKIVDKVSGIDKNEGRKHKLYGITNADLEVFLFLHKKCNTYGELSHVSIHMLWEDYKNYKEAFAHIHHSQFYVALKKLSFHNIITIENEYSGKYKITLTDFMNKETNKANAYTFISPIVFTKEFFELSIAAKKLFMDVAMQQKRETTLKRSLFKVDEQGNSTHFGGMYRYLHKKYPHQIRAVLEELETKLSATGSPLFKICKLEKGKKNKKQYTTLHLSVHPDFLCAKEEGAEYRDPFTPRDTYKRKVKFIENLLVEMNIAEFAKDMNQFINVLKHSCHRQIRQVVRGLREMIDRQEGYPKKLVYTLSKLLKQSSQYRVLDTAAKTGIYPLITHNVPKHEQEEAIFKFGTHFAIYSLRNVQKLFRKAHDLLHAKYAVPVTLDAYHRNYMQYQEESLFRKYAYEQGVNINAYTALEIEIRELLKSSGHQGTNMPSDIRELFIEKVDKLSKEKIRVIEVPEDFDLIQFLQSLEAYYRSTSETPHSVDQLLPAM
>NC_018689.1|WP_000413552.1|286987_288397_+|NADP-dependent-phosphogluconate-dehydrogenase
MEKLQIGVVGVGVMGKSLALNFESKGYSVALYDISKEKVDEIIEENRGKNLVGTHIVEEFVNSLESPRKILLMVNAGEITDKAIDSLVPHLDKGDILIDGGNTYFVDTIRRNKRLAEEGINFIGAGVSGGEEGALKGPSIMPGGQKDAYEKVKDMLENISAKVNNEPCCSYIGPNGAGHYVKMVHNGIEYGDMQLICEAYFFLKQTLDLTAEEFHEIFVEWNKGELNSYLIEITADIFKKKDEETGKPLVDVILDTAGQKGTGKWTSQSALDLGISLPIITESVFARCISALKEERVNASKVLSGPKDKTAIGVEKAELIEAVRQALYMSKICSYAQGFTQLKAASEEYDWNLDFGSISMLWRGGCIIRAAFLQNIKEAYETNTELPNLLLDPYFKEIVESYQGGLRQIISMAVQQGIPIPAFSAAISYYDSYRTAKLPANLLQAQRDYFGAHTYKRVDKEGTFHTKWI
>NC_018689.1|WP_001131717.1|285376_286723_+|gluconate-permease-GntP
MPLVIVAIGILALLLLIMRFKLNTFISLIIVSVGVALALGMPPEKIFKTIEAGLGGTLGHLALVFGLGAMLGKLLSDSGGAQRIAMTLVKKFGEKNIQWAVVTASFIIGIALFFEVGLVLLIPIVFAISRELKVSILYLGISMAAALSVTHGFLPPHPGPTAIAGELHANIGEVLLYGFMIAVPTVVLAGPVFTKLAKKLVPDAFTKTGNIKSLGEQKVFKLEETPGFGISVFTALLPVLLMAVATIITLLQKTMGFKDNSLLATIEFIGNADTAMLISLLVAIYTMGLARNIPIKNVMESCTTAISNIGMMLLIIGGGGAFKQVLIDGGVGNYVAELFKGTSLSPILLAWIIAAILRISLGSATVAALTTVGLVIPMLGQSDVNLALVVLATGAGSLIASHVNDAGFWMFKEYFGLSMKETFATWTLLETIVSVAGLGFTLLLSLFV
>NC_018689.1|WP_000100536.1|283724_285260_+|gluconokinase
MSSYMLGIDIGTTSTKAVLFTEKGEVIQTENIGYPLRTPDISTAEQDPEEIFQAVLQAISNITKQHSDKKPSFISFSSAMHSVIAMDENDQPLTPCITWADNRSEAWAHKIKDELNGHEVYRRTGTPIHPMSPLSKITWIVNAHPEIAIRTKKYIGIKEYIFKQFFDQYVVDHSIASCMGMMNLKTLDWDEEALKIAGITSAQLSELVPTTQIFSNCNPDLAQKIGIDSQTPFVIGASDGVLSNLGVNAIRKGEIAVTIGTSGAIRTIIDKPQTDKKGRIFCYALTEKHWVIGGPVNNGGMVLRWIRDELASSEVETAKRLGIDPYDVLTKIAERVRPGADGLLFHPYLAGERAPLWNPDVRGSFFGLTMSHKKEHMIRAALEGVIYNLYTVFLALTECMDGPVTRIQATGGFARSDVWRQMMSDIFASEVVVPKSYESSCLGACILGLYATGKIDSFEIVSEMVGSTYKHTPKEEATKEYRQLLPIFINLSRALEDDYTRIANYQRNLIK
>NC_018689.1|WP_001130026.1|283000_283732_+|gluconate-operon-transcriptional-repressor-GntR
MAKSMEFLYPEKWLSKASTGDRVASELRMRIIAGEIESGTILSENKLAADFSVSRSPVREALKVLASENIIRLERMGAVVIGLTEKEIEEIYDVRLLIETFIFERLVKMDTNDLVRELNKIMEMMKIAIKYHDSDEFSYQDLLFHETIIRTIEHSYILMIWNNLKPVMESLILLSMRTRFKEKYEDFERIIKNHELYIKAIESKDRALMIKALHQNFDDVQGKVEDFWMSQQMLSKGVEQGHE
>NC_018689.1|WP_014990771.1|304309_304972_+|C40-family-peptidase
MGEKVEITSKLYLSLYGTGYANYAVSKGGYTHENARAFSAEQSAKNGYRCASWRSAEAVANNWCYGDPDYVPHIMRYYQPGQTPGGSGGIAGGSVLGDDVFQAIMAEALKYQGWPYVFGGRIPNTSFDCSGIIEYTYSRVSINLFGTAQTQWDKTQRITDPKPGDLVFFHSTYATSNYITHVGIYVGNNTMYHAGDPIGYADLGKPYFQQHFAGYGRVVR
>NC_018689.1|WP_000724398.1|305023_305620_+|hypothetical-protein
MKKITIIIAILLIVSVGFLIKYQSDNEKLKTDNIKLTKKVEKVEAQYNDTKKELSALKSNNQQQVKEAAERFLKAFRTYDTGKGESYLANIDAYITPNAKKELTPPGGPTQSAPGAGDEKEKKKVSFQSEYTGGELYYAFLDTTEANVLAKVKSKITVNGVSSDNMSLMQINLIYDGNKKLWLVDKLIPLADLRDQMP
>NC_018689.1|WP_000428112.1|305872_306175_-|hypothetical-protein
MENKEILLAITELKSSIDKRFDALEKQFDKRLDSVSEELYKIKQNLVTVDGQQSEDTQKQIDKIEKDIKILNQDVMFLAGKLGVHDLKLIGIENKTYIKR
>NC_018689.1|WP_000312828.1|306241_306616_-|hypothetical-protein
MAYDNTFSCIKLTEEQYVKAVELLEKFKKESIYNFEVRPLDVVRNSIQTTHYFIIEMNLSREDLERLIMENNELKLRNNELTEEHNLYKYKIKELTLKNEELTKRLEKEKIKYLQQANFNRITS
>NC_018689.1|WP_000377606.1|307591_308461_+|hypothetical-protein
MDSKTYEKLQALRRYKEPIQAVLRTVKRHDKDDSDTEYAEFALENGKVIGICKKEDFSDYSFRSITQFTGNIFNVVITQMSDELDVNKVQVSVKEASRRSADALIRELIELEQVERLQEPTYEAEVTGYNINAQVPTIFLRINGAECFMKLHELNYGRVYKNAVDRYAPIGERIPVKVLQFNPEQRLIHVSRKAAMENPYQLLSELTEGDTIVGRVVNVDPRFGVFVELDQGCTIKGIVPKTIEQPVLDDVVSMRIVSVDVEKERGSGVIFKFPFGRKKVNDPTAFLYN
>NC_018689.1|WP_001275775.1|308460_309432_+|hypothetical-protein
MSAPQVSVQENGKAVQYWLNRDESLSLWDDPSLQGGPILPDKFKPLTDLRSIYDRINSGFINEKDNLILKLIWDSLAITEAQIKNFVESKISRSQVSESLKKLVLYGFVSRWEIKSALFPDQPKISAPITLNTAGYLMMWAYHNRNTNYSLKPEQWLRFGVAGVQRFVTMNQIKYEFAVGQQLLKNWCWYPKLKGTGNGYNPIAVGEIKTPIGNQNFIFERVQQGQRYAQHLKSRLKIWEDHIQNGPNNLLNFENTKSLPGIFILSISNLALAEHVRKELMLDLRKIPIMLVIDECIHSEGFAKSFYISTQKGIQQAPLPFLR
>NC_018689.1|WP_079995239.1|310661_310763_-|YjcZ-family-sporulation-protein
MGFGGSCGSCGGGFALLVVLFILLIIVGASCFC
>NC_018689.1|WP_001277524.1|311494_311791_+|helix-turn-helix-transcriptional-regulator
MSCDFNMDSSDYKSSSKILELLGSPSRLLIVCELIVSGTLTVSQLSTATHISEPMILQHLRKLTIGNIVISERKGTRLYCRVEDKKVIEITELLGLAH
>NC_018689.1|WP_000693609.1|313317_313596_+|hypothetical-protein
MKIKFGVVKDENFDFTLLGTKLLKTFKEVDQVAIVEKVEDKIFEKDDVQIHLAEITINVTGKNIGYRSVSASIFIVLESLSIKLFNINISIH
>NC_018689.1|WP_001216134.1|314198_314384_+|hypothetical-protein
MRHKKDLLKQWKVDLQAVQKEKRMKKKAKNKKYSIPGNAAGFMNGKNTYRKENGVWKQRNK

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018689_1	1.1\|300051\|35\|NC_018689\|CRISPRCasFinder	300051-300085	35	NC_018689	Bacillus thuringiensis MC28 plasmid pMC429, complete sequence	300051-300085	0	1.0
NC_018689_1	1.1\|300051\|35\|NC_018689\|CRISPRCasFinder	300051-300085	35	NZ_CP029455	Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence	157156-157190	1	0.971
NC_018689_1	1.1\|300051\|35\|NC_018689\|CRISPRCasFinder	300051-300085	35	CP002509	Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB26, complete sequence	101702-101736	1	0.971
NC_018689_1	1.1\|300051\|35\|NC_018689\|CRISPRCasFinder	300051-300085	35	NC_014172	Bacillus thuringiensis BMB171 plasmid pBMB171, complete sequence	112825-112859	1	0.971
NC_018689_1	1.1\|300051\|35\|NC_018689\|CRISPRCasFinder	300051-300085	35	NZ_CP009691	Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence	283995-284029	1	0.971
NC_018689_1	1.1\|300051\|35\|NC_018689\|CRISPRCasFinder	300051-300085	35	NZ_CP015592	Bacillus cereus strain AR156 plasmid pAR460, complete sequence	448056-448090	2	0.943
NC_018689_1	1.1\|300051\|35\|NC_018689\|CRISPRCasFinder	300051-300085	35	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	6536-6570	2	0.943

1. spacer 1.1|300051|35|NC_018689|CRISPRCasFinder matches to NC_018689 (Bacillus thuringiensis MC28 plasmid pMC429, complete sequence) position: , mismatch: 0, identity: 1.0

ggatgttaaaccagtagcgcaatcaaatgaggaac	CRISPR spacer
ggatgttaaaccagtagcgcaatcaaatgaggaac	Protospacer
***********************************

2. spacer 1.1|300051|35|NC_018689|CRISPRCasFinder matches to NZ_CP029455 (Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence) position: , mismatch: 1, identity: 0.971

ggatgttaaaccagtagcgcaatcaaatgaggaac	CRISPR spacer
ggatgttaaaccagtagcgcaatcaaatgaggaat	Protospacer
**********************************.

3. spacer 1.1|300051|35|NC_018689|CRISPRCasFinder matches to CP002509 (Bacillus thuringiensis serovar finitimus YBT-020 plasmid pBMB26, complete sequence) position: , mismatch: 1, identity: 0.971

ggatgttaaaccagtagcgcaatcaaatgaggaac	CRISPR spacer
ggacgttaaaccagtagcgcaatcaaatgaggaac	Protospacer
***.*******************************

4. spacer 1.1|300051|35|NC_018689|CRISPRCasFinder matches to NC_014172 (Bacillus thuringiensis BMB171 plasmid pBMB171, complete sequence) position: , mismatch: 1, identity: 0.971

ggatgttaaaccagtagcgcaatcaaatgaggaac	CRISPR spacer
ggacgttaaaccagtagcgcaatcaaatgaggaac	Protospacer
***.*******************************

5. spacer 1.1|300051|35|NC_018689|CRISPRCasFinder matches to NZ_CP009691 (Bacillus mycoides strain ATCC 6462 plasmid pBMX_1, complete sequence) position: , mismatch: 1, identity: 0.971

ggatgttaaaccagtagcgcaatcaaatgaggaac	CRISPR spacer
ggatgttaaaccagtagcgcaatcaaacgaggaac	Protospacer
***************************.*******

6. spacer 1.1|300051|35|NC_018689|CRISPRCasFinder matches to NZ_CP015592 (Bacillus cereus strain AR156 plasmid pAR460, complete sequence) position: , mismatch: 2, identity: 0.943

ggatgttaaaccagtagcgcaatcaaatgaggaac	CRISPR spacer
ggatgttaaaccagtagcgcaatcaaacgatgaac	Protospacer
***************************.** ****

7. spacer 1.1|300051|35|NC_018689|CRISPRCasFinder matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 2, identity: 0.943

ggatgttaaaccagtagcgcaatcaaatgaggaac	CRISPR spacer
ggatgttaaaccagtagcgcaatcaaacgatgaac	Protospacer
***************************.** ****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

250250 : 258760

Bacillus_phage(88.89%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001043915.1\|250250_250460_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	7.7e-14	59.4
WP_000376551.1\|251063_251201_+	DUF3956 domain-containing protein	NA	NA	NA	NA
WP_000513195.1\|251331_251616_-	hypothetical protein	A0A1B1P857	Bacillus_phage	2.1e-30	76.7
WP_000462901.1\|251960_252152_-	hypothetical protein	NA	NA	NA	NA
WP_000441076.1\|252386_252548_-	hypothetical protein	NA	NA	NA	NA
WP_001000165.1\|253378_253543_+	hypothetical protein	A0A288WGN0	Bacillus_phage	2.6e-09	55.6
WP_001008433.1\|254692_254941_+	hypothetical protein	A0A288WFY7	Bacillus_phage	3.5e-29	79.3
WP_000776806.1\|255323_255770_-	dUTP diphosphatase	A0A0U3SLD3	Bacillus_phage	1.4e-60	79.1
WP_000712300.1\|255810_255951_-	hypothetical protein	A0A0U3SD36	Bacillus_phage	1.7e-12	87.0
WP_080451858.1\|256018_256150_-	Fur-regulated basic protein FbpA	NA	NA	NA	NA
WP_043324812.1\|256246_256510_-	hypothetical protein	W8CYZ5	Bacillus_phage	1.4e-20	56.8
WP_181004292.1\|256479_256551_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_000516004.1\|256759_257278_+	DUF4352 domain-containing protein	A0A1B1P898	Bacillus_phage	3.5e-47	74.6
WP_000540766.1\|257571_258132_+	DUF4236 domain-containing protein	NA	NA	NA	NA
WP_000476456.1\|258331_258760_+	hypothetical protein	A0A0K2CZD8	Paenibacillus_phage	8.4e-23	43.3

DBSCAN-SWA_2

318773 : 326951

Bacillus_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001214906.1\|318773_319094_+	hypothetical protein	A0A0S2GLK1	Bacillus_phage	1.3e-31	68.0
WP_000767011.1\|319104_320271_+	DNA translocase FtsK	A0A0S2GLG9	Bacillus_phage	6.2e-177	78.6
WP_014990779.1\|320311_320869_+	replication-relaxation family protein	W8CZ47	Bacillus_phage	9.8e-80	75.1
WP_000760455.1\|320958_321294_+	YxeA family protein	NA	NA	NA	NA
WP_000799428.1\|321714_322362_+	lysozyme family protein	A0A223LKM8	Bacillus_phage	5.2e-16	33.2
WP_043324884.1\|322661_324125_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	9.0e-24	29.7
WP_000800731.1\|324138_324804_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.7e-36	36.1
WP_000050963.1\|324967_325144_+	hypothetical protein	NA	NA	NA	NA
WP_000494789.1\|325742_326951_+	trypsin-like peptidase domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	1.5e-24	31.9

DBSCAN-SWA_3

358204 : 374836

Bacillus_phage(42.86%)

terminase,capsid,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000477260.1\|358204_359026_+	hypothetical protein	F2NZ47	Diadromus_pulchellus_ascovirus	1.5e-23	29.8
WP_001046354.1\|359030_359423_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_000764188.1\|359576_360101_+	ester cyclase	NA	NA	NA	NA
WP_000834515.1\|360639_361284_-	helix-turn-helix domain-containing protein	A0A2H4J245	uncultured_Caudovirales_phage	3.1e-29	34.3
WP_000549411.1\|361421_361622_+	helix-turn-helix transcriptional regulator	W8CYN7	Bacillus_phage	1.7e-10	51.7
WP_000231465.1\|362152_362437_+	hypothetical protein	NA	NA	NA	NA
WP_000096620.1\|362517_363282_+	conserved phage C-terminal domain-containing protein	A0A1W6JNI1	Staphylococcus_phage	7.9e-56	49.2
WP_176548852.1\|363265_364048_+	ATP-binding protein	U5PWH5	Bacillus_phage	3.3e-33	35.6
WP_001261480.1\|364283_364922_+	hypothetical protein	X2JKZ4	Bacillus_phage	7.9e-09	28.6
WP_000765289.1\|364902_365079_+	Fur-regulated basic protein FbpA	NA	NA	NA	NA
WP_000931949.1\|365142_365523_+	hypothetical protein	A0A0M4R397	Bacillus_phage	1.4e-16	42.7
WP_001205172.1\|365793_366294_+	sigma-70 family RNA polymerase sigma factor	A0A0A7AQW8	Bacillus_phage	2.2e-46	60.4
WP_000892958.1\|366527_366713_+	hypothetical protein	NA	NA	NA	NA
WP_000113634.1\|366730_367222_+	hypothetical protein	A0A1B0XTP0	Freshwater_phage	1.8e-05	22.8
WP_043324840.1\|367402_368659_+\|terminase	phage terminase large subunit	A0A2H4J7G6	uncultured_Caudovirales_phage	2.2e-111	51.1
WP_000229506.1\|368752_370093_+\|portal	phage portal protein	A0A222YY66	Streptomyces_phage	4.5e-46	29.3
WP_001132396.1\|370121_371312_+	hypothetical protein	A0A1B1P7E4	Bacillus_phage	3.2e-35	31.1
WP_001060156.1\|371332_372313_+\|capsid	phage major capsid protein	H7BVA6	unidentified_phage	3.6e-69	41.4
WP_080595761.1\|372329_372494_+	YqbF domain-containing protein	NA	NA	NA	NA
WP_000406976.1\|372507_373041_+	hypothetical protein	NA	NA	NA	NA
WP_000392019.1\|373069_373396_+	hypothetical protein	NA	NA	NA	NA
WP_033663286.1\|373397_373814_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_000208341.1\|373810_374227_+	hypothetical protein	NA	NA	NA	NA
WP_000118566.1\|374239_374836_+	hypothetical protein	A0A1S5S9Y8	Streptococcus_phage	5.3e-15	31.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_018688

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

269814 : 276349

Bacillus_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000987741.1\|269814_270426_-	replication-relaxation family protein	W8CZ47	Bacillus_phage	1.2e-86	75.1
WP_000522930.1\|270415_271582_-	DNA translocase FtsK	A0A0S2GLG9	Bacillus_phage	7.6e-183	80.2
WP_000958236.1\|271592_271787_-	hypothetical protein	A0A1B1P7T1	Bacillus_phage	4.2e-14	56.2
WP_000467346.1\|272004_272229_+	helix-turn-helix domain-containing protein	A0A0A7AR43	Bacillus_phage	3.6e-17	54.4
WP_148283640.1\|272321_272834_-	hypothetical protein	NA	NA	NA	NA
WP_000424045.1\|273375_273615_-	hypothetical protein	A0A1B1P8F3	Bacillus_phage	1.0e-06	38.6
WP_000483141.1\|274369_276349_-	DUF3472 domain-containing protein	G1FGA4	Mycobacterium_phage	7.2e-08	40.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_018694

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

34879 : 54484

Bacillus_phage(71.43%)

terminase,integrase,portal

attL 38118:38131|attR 52567:52580

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001092095.1\|34879_35224_-	helix-turn-helix transcriptional regulator	A0A2H4JAY7	uncultured_Caudovirales_phage	2.8e-08	35.9
WP_001161769.1\|35819_37007_+	hypothetical protein	D2XQ10	Bacillus_virus	1.7e-89	48.7
WP_000837442.1\|37026_37167_+	hypothetical protein	NA	NA	NA	NA
WP_001099889.1\|37331_37511_+	hypothetical protein	NA	NA	NA	NA
WP_001213815.1\|37531_37870_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000667090.1\|38074_38293_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
38118:38131	attL	NA	NA	NA	NA
WP_000088808.1\|38368_39043_+	Rha family transcriptional regulator	A0A0U4IS08	Exiguobacterium_phage	3.0e-35	41.0
WP_001121079.1\|39066_39429_+	hypothetical protein	A0A0S2MVA8	Bacillus_phage	7.6e-41	67.8
WP_000521761.1\|39451_39799_+	hypothetical protein	A0A0S2MVM3	Bacillus_phage	4.7e-24	56.5
WP_000348869.1\|39987_40488_+	hypothetical protein	A0A0A7AQW2	Bacillus_phage	4.1e-61	72.4
WP_000139416.1\|40456_40873_+	hypothetical protein	A0A0S2MVI0	Bacillus_phage	1.7e-44	63.5
WP_000706095.1\|40875_41343_+	hypothetical protein	A0A0A7AR00	Bacillus_phage	3.4e-33	45.8
WP_000667212.1\|41549_41831_+	hypothetical protein	A0A0S2MVD9	Bacillus_phage	8.2e-19	56.2
WP_000843532.1\|41827_42277_+	hypothetical protein	A0A0S2MVJ1	Bacillus_phage	5.8e-67	79.3
WP_001216591.1\|42273_42855_+	dUTP diphosphatase	A0A0S2MVD0	Bacillus_phage	2.6e-91	82.4
WP_000841932.1\|42876_43425_+	hypothetical protein	A0A0S2MVC3	Bacillus_phage	4.4e-101	96.2
WP_000417534.1\|43483_43675_+	hypothetical protein	NA	NA	NA	NA
WP_000784798.1\|43707_43920_+	hypothetical protein	NA	NA	NA	NA
WP_001139625.1\|43907_44165_+	hypothetical protein	NA	NA	NA	NA
WP_000362235.1\|44589_44793_+	hypothetical protein	A0A1B1P8C8	Bacillus_phage	9.8e-30	95.5
WP_000074682.1\|44980_45172_+	hypothetical protein	NA	NA	NA	NA
WP_000540404.1\|45429_45960_+	Holliday junction resolvase RecU	A0A1C8E9C3	Bacillus_phage	5.1e-78	81.2
WP_000414269.1\|45959_46304_+	zinc-finger domain-containing protein	A0A0A7AR67	Bacillus_phage	4.0e-23	47.2
WP_000654043.1\|46448_46949_+	sigma-70 family RNA polymerase sigma factor	A0A0S2MVE1	Bacillus_phage	3.3e-71	80.6
WP_000849232.1\|47224_47773_+	hypothetical protein	NA	NA	NA	NA
WP_001263205.1\|48589_48814_+	hypothetical protein	NA	NA	NA	NA
WP_000451524.1\|49301_49721_+	helix-turn-helix domain-containing protein	A0A142F1N8	Bacillus_phage	1.7e-07	55.6
WP_000673899.1\|49878_50421_+\|integrase	site-specific integrase	A0A1B0T6D2	Bacillus_phage	3.2e-43	49.2
WP_000390791.1\|50635_50815_+	hypothetical protein	NA	NA	NA	NA
WP_000113809.1\|50836_51664_+\|terminase	terminase	A0A1L2JY44	Aeribacillus_phage	1.1e-34	38.1
WP_000038941.1\|51656_52934_+\|terminase	PBSX family phage terminase large subunit	S5MC58	Brevibacillus_phage	3.6e-154	64.2
52567:52580	attR	NA	NA	NA	NA
WP_001280902.1\|53002_54484_+\|portal	phage portal protein	O80200	Methanobacterium_phage	1.2e-31	29.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NC_018685

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

15185 : 78176

Bacillus_phage(30.77%)

integrase,transposase

attL 8505:8520|attR 77293:77308

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
8505:8520	attL	NA	NA	NA	NA
WP_000219643.1\|15185_16112_-\|integrase	site-specific integrase	A0A1B1P793	Bacillus_phage	1.4e-70	45.2
WP_000926057.1\|17489_18500_-	hypothetical protein	NA	NA	NA	NA
WP_001110318.1\|18954_20124_+	hypothetical protein	A0A1B1P895	Bacillus_phage	2.0e-21	23.8
WP_000443950.1\|20385_20526_+	hypothetical protein	NA	NA	NA	NA
WP_000369750.1\|20581_20974_-	helix-turn-helix domain-containing protein	A0A139ZPK3	Marinitoga_camini_virus	4.3e-05	34.4
WP_000881124.1\|21081_21315_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000243352.1\|21496_24037_+	Cys-Gln thioester bond-forming surface protein	NA	NA	NA	NA
WP_000334855.1\|24071_24257_+	hypothetical protein	NA	NA	NA	NA
WP_000333864.1\|24289_24826_+	type IV secretion system DNA-binding domain-containing protein	NA	NA	NA	NA
WP_000802607.1\|24886_25069_+	hypothetical protein	NA	NA	NA	NA
WP_000517905.1\|25128_25368_+	hypothetical protein	NA	NA	NA	NA
WP_000951341.1\|25400_28205_+	hypothetical protein	NA	NA	NA	NA
WP_000526863.1\|28210_29053_+	replication-relaxation family protein	NA	NA	NA	NA
WP_000488222.1\|29057_29273_+	hypothetical protein	NA	NA	NA	NA
WP_001146809.1\|29276_29498_+	hypothetical protein	NA	NA	NA	NA
WP_000494039.1\|29530_29812_+	hypothetical protein	NA	NA	NA	NA
WP_000487024.1\|30015_30993_+	conjugal transfer protein	NA	NA	NA	NA
WP_000281809.1\|31002_31254_+	hypothetical protein	NA	NA	NA	NA
WP_000659764.1\|31281_31833_+	conjugal transfer protein	NA	NA	NA	NA
WP_000920941.1\|31792_34363_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	3.8e-86	28.5
WP_000736224.1\|34421_34931_+	hypothetical protein	NA	NA	NA	NA
WP_000732811.1\|34927_37684_+	hypothetical protein	NA	NA	NA	NA
WP_000683506.1\|37741_38140_+	hypothetical protein	NA	NA	NA	NA
WP_001247221.1\|38167_39295_+	peptidoglycan DD-metalloendopeptidase family protein	A0A2D0ZM66	Rhodococcus_phage	2.2e-17	40.6
WP_000808984.1\|39319_39904_+	hypothetical protein	NA	NA	NA	NA
WP_000610003.1\|39921_40242_+	hypothetical protein	NA	NA	NA	NA
WP_000636254.1\|40266_40563_+	hypothetical protein	NA	NA	NA	NA
WP_000575853.1\|40690_41011_+	hypothetical protein	NA	NA	NA	NA
WP_000581807.1\|41043_41256_+	hypothetical protein	NA	NA	NA	NA
WP_000070888.1\|41872_42763_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_000658054.1\|43180_43354_-	hypothetical protein	NA	NA	NA	NA
WP_014990401.1\|43645_44938_-	hypothetical protein	NA	NA	NA	NA
WP_001120840.1\|45977_47516_-	NAD(P)/FAD-dependent oxidoreductase	A0A2K9L3H9	Tupanvirus	4.7e-15	24.6
WP_000843031.1\|48898_49180_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	5.2e-13	65.6
WP_000448511.1\|49200_49434_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_001043043.1\|49486_49765_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	6.7e-21	62.2
WP_000786134.1\|49915_50206_+	helix-turn-helix transcriptional regulator	A0A218MNF3	uncultured_virus	7.0e-05	36.2
WP_000016447.1\|50275_50584_+	hypothetical protein	NA	NA	NA	NA
WP_001075554.1\|50946_51876_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_000576875.1\|51960_52296_-	hypothetical protein	NA	NA	NA	NA
WP_001032323.1\|52391_52601_-	hypothetical protein	NA	NA	NA	NA
WP_000273149.1\|52799_53504_-	hypothetical protein	A0A0A7RTR8	Clostridium_phage	2.1e-39	37.4
WP_001199493.1\|54052_54694_+	recombinase family protein	A0A1B0VBM1	Salmonella_phage	2.8e-14	33.2
WP_014990407.1\|56025_57414_-	phosphatidylinositol-specific phospholipase C domain-containing protein	NA	NA	NA	NA
WP_148283627.1\|59139_62628_+	hypothetical protein	NA	NA	NA	NA
WP_000377014.1\|63341_64742_-	phosphatidylinositol-specific phospholipase C	NA	NA	NA	NA
WP_000730143.1\|65139_65712_-	hypothetical protein	NA	NA	NA	NA
WP_148283626.1\|66710_66851_+	amino acid adenylation	NA	NA	NA	NA
WP_001053994.1\|69384_70818_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_000711950.1\|71692_72400_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.4e-38	44.4
WP_000162158.1\|72516_74943_-	hypothetical protein	NA	NA	NA	NA
WP_001056253.1\|76304_76832_+	DUF642 domain-containing protein	NA	NA	NA	NA
WP_087951311.1\|77013_78176_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	4.6e-39	39.7
77293:77308	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NC_018693

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_018693_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018693_1

749187-749279

Orphan

Consensus_repeat	Method
ACAAAACACCTTAGTTGAAGGCATTATTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018693_1

>merge|NC_018693|1|749187-749279|CRISPRCasFinder
ACAAAACACCTTAGTTGAAGGCATTATTAGTGAGGGGTATTTTATTTGAAGTATCAAAAGGTTAACAAAACACTTTAGTTGAAGGCATTATTA

>NC_018693|1|1|749187-749279|CRISPRCasFinder
ACAAAACACCTTAGTTGAAGGCATTATTA	GTGAGGGGTATTTTATTTGAAGTATCAAAAGGTTA
ACAAAACACTTTAGTTGAAGGCATTATTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018693.1\|WP_000812303.1\|751795_752611_+\|hypothetical-protein	unknown	unknown	unknown
NC_018693.1\|WP_000172731.1\|754112_754502_+\|hypothetical-protein	unknown	unknown	unknown
NC_018693.1\|WP_000101607.1\|754501_756079_+\|bacteriophage-terminase-large-subunit	unknown	unknown	gnl\|CDD\|222858
NC_018693.1\|WP_000022953.1\|751397_751571_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_018693.1\|WP_000869384.1\|743985_744540_+\|DUF1273-domain-containing-protein	unknown	unknown	gnl\|CDD\|237461
NC_018693.1\|WP_000887343.1\|750409_751291_+\|DUF5309-domain-containing-protein	unknown	unknown	gnl\|CDD\|379950
NC_018693.1\|WP_000301968.1\|752927_753902_+\|hypothetical-protein	unknown	unknown	unknown
NC_018693.1\|WP_001252045.1\|741848_742091_+\|hypothetical-protein	unknown	unknown	unknown
NC_018693.1\|WP_000455491.1\|742106_742451_+\|YppE-family-protein	unknown	unknown	gnl\|CDD\|378052
NC_018693.1\|WP_000658722.1\|749451_749643_+\|hypothetical-protein	unknown	unknown	unknown
NC_018693.1\|WP_000966030.1\|746889_747804_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|274042
NC_018693.1\|WP_000886367.1\|749681_749903_+\|hypothetical-protein	unknown	unknown	unknown
NC_018693.1\|WP_043322869.1\|740393_741419_+\|DUF2515-domain-containing-protein	unknown	unknown	gnl\|CDD\|371209
NC_018693.1\|WP_000242658.1\|742476_742668_-\|YppF-family-protein	unknown	unknown	gnl\|CDD\|290882
NC_018693.1\|WP_000485081.1\|752642_752846_+\|hypothetical-protein	unknown	unknown	unknown
NC_018693.1\|WP_000521231.1\|745632_746772_+\|class-I-SAM-dependent-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|223194
NC_018693.1\|WP_000546285.1\|743512_743929_+\|spore-coat-protein	unknown	unknown	gnl\|CDD\|371387
NC_018693.1\|WP_000487695.1\|742845_743355_+\|YppG-family-protein	unknown	unknown	gnl\|CDD\|372950
NC_018693.1\|WP_000343505.1\|749926_750388_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373570
NC_018693.1\|WP_000622427.1\|744637_744973_+\|cell-division-regulator-GpsB	unknown	unknown	gnl\|CDD\|237616

Protein	Function_ID	Function_description	E-value
NC_018693.1\|WP_000101607.1\|754501_756079_+\|bacteriophage-terminase-large-subunit	gnl\|CDD\|222858	PHA02533, 17, large terminase protein; Provisional.	5.00618e-39
NC_018693.1\|WP_000022953.1\|751397_751571_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	7.82949e-07
NC_018693.1\|WP_000869384.1\|743985_744540_+\|DUF1273-domain-containing-protein	gnl\|CDD\|237461	PRK13660, PRK13660, hypothetical protein; Provisional.	3.12501e-101
NC_018693.1\|WP_000887343.1\|750409_751291_+\|DUF5309-domain-containing-protein	gnl\|CDD\|379950	pfam17236, DUF5309, Family of unknown function (DUF5309). This is a family of uncharacterized proteins found in viruses and bacteria.	2.71519e-92
NC_018693.1\|WP_000455491.1\|742106_742451_+\|YppE-family-protein	gnl\|CDD\|378052	pfam08807, DUF1798, Bacterial domain of unknown function (DUF1798). This domain is found in many hypothetical proteins. The structure of one of the proteins in this family has been solved and it adopts an all alpha helical fold.	4.63755e-35
NC_018693.1\|WP_000966030.1\|746889_747804_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	3.2144e-35
NC_018693.1\|WP_043322869.1\|740393_741419_+\|DUF2515-domain-containing-protein	gnl\|CDD\|371209	pfam10720, DUF2515, Protein of unknown function (DUF2515). This family is conserved in Firmicutes. Several members are annotated as YppC. The function is not known.	2.97705e-165
NC_018693.1\|WP_000242658.1\|742476_742668_-\|YppF-family-protein	gnl\|CDD\|290882	pfam14178, YppF, YppF-like protein. The YppF-like protein family includes the B. subtilis YppF protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length. There is a conserved LLDF sequence motif.	6.15891e-26
NC_018693.1\|WP_000521231.1\|745632_746772_+\|class-I-SAM-dependent-RNA-methyltransferase	gnl\|CDD\|223194	COG0116, COG0116, Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair].	0
NC_018693.1\|WP_000546285.1\|743512_743929_+\|spore-coat-protein	gnl\|CDD\|371387	pfam11122, Spore-coat_CotD, Inner spore coat protein D. This family is conserved in the Enterobacteriaceae family. CotD is an inner spore coat protein that is expressed in the middle phase of mother cell gene expression. Along with CotD, CotH, CotS and CotT it is assumed to assemble into the loose skeleton of the matrix, between the shells of SpoIVA and CotE. Coat proteins do not share much sequence similarity between species, but this does not imply they do not share secondary, tertiary, or quaternary features.	1.46357e-13
NC_018693.1\|WP_000487695.1\|742845_743355_+\|YppG-family-protein	gnl\|CDD\|372950	pfam14179, YppG, YppG-like protein. The YppG-like protein family includes the B. subtilis YppG protein, which is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 115 and 181 amino acids in length. There are two completely conserved residues (F and G) that may be functionally important.	9.79032e-10
NC_018693.1\|WP_000343505.1\|749926_750388_+\|hypothetical-protein	gnl\|CDD\|373570	pfam15112, DUF4559, Domain of unknown function (DUF4559). This family of proteins is functionally uncharacterized. This family of proteins is found in eukaryotes. This family includes human protein CXorf38.	6.21544e-05
NC_018693.1\|WP_000622427.1\|744637_744973_+\|cell-division-regulator-GpsB	gnl\|CDD\|237616	PRK14127, PRK14127, cell division regulator GpsB.	4.95408e-44

>NC_018693.1|WP_000966030.1|746889_747804_+|tyrosine-type-recombinase/integrase
MLYKIAMQEFLDDRELRNLSKHTLKSYKGILKRFESFCVNKGIFDTDKVTSKVAKEFLIYCKHELKNSISTINEKNRTLKVYFKYLEEEGIVEENPFKKIKFSKEDTITDVLTDEQVKSVLEHFDRGHYKGTNFALMRNRMVIVLLISTGLRREELVNLKWSDIDMRNRTIMTYGKKRTVATIPYTRKLQKELAEYKTFLEFYFEEEKEVVYVFPDKWNRQLTTEAISTLFKRLKRNLNMEGLTCHAFRRYFASKCLKMGMDSLNLQKLMRHETLQMTERYVKLYGHALHDVNDKYNPLNFIEV
>NC_018693.1|WP_000521231.1|745632_746772_+|class-I-SAM-dependent-RNA-methyltransferase
MGKVTLIATAAMGIEALVAREVRDLGYECQVENSKVTFEADEKAICRTNLWLRTADRVKIKVGEFKATTFDELFEKTKALNWGDYIPENGEFPVIGKSLKSELFSVSDCQRIVKKAVVEKLKTTYKRTTWFEEDGPLFRIEIAMLKDIATLTIDASGVGLHKRGYRMDQGEAPLKETLAASLIKLTNWKPDRPFVDPFCGSGTIPIEAALIGQNIAPGFNRGFASDEWGWVGKQNWREARQEAEDLANYNQPLQIIGSDIDHRMIRVAQENAEEVGLGDLITFKQMQVKDFTTKEDYGYVVTNPPYGERLSEKALVEQLYKEMGQVFRPLDTWSAYVLTSYEAFEKCYGKDASKKRKLFNGFIRTDYYQYFGKRPPRNS
>NC_018693.1|WP_000622427.1|744637_744973_+|cell-division-regulator-GpsB
MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEAFHKEFDQLKQQNVRLKRELEEQKLAATQAPQQPVQTPVAQPVYNNTNTDILKRLSNLEKAVFGSKLYE
>NC_018693.1|WP_000869384.1|743985_744540_+|DUF1273-domain-containing-protein
MKVVAVTGYKPFELGIFKKDHPGVDCIKKALHRKLTAFVEDGLEWVIISGQLGVELWAAEVVFEIQVEYPDLKLAVFTPFLEQEENWKEDNREYYEFILSQADHIDSITKRKYESPEQFKLKNQFFIEKSDALLAVYDEEKPGSPKYIVEVAKKKGEIENYHSYFILFSDLQDIIEEEQWNNAE
>NC_018693.1|WP_000546285.1|743512_743929_+|spore-coat-protein
MHHCHPCFGGHKPVGPICTTAPVIHPTKQCVTHSFSTTVVPHIFPTHTTHVHHQQIKNQNFFPQTNSNVNVVDPIDPGFGGGCGPCGHGHHHHGHQISPFGPGPNVSPFGPGPNVSPFGPGPNVGPNVGPNVGGIFKK
>NC_018693.1|WP_000487695.1|742845_743355_+|YppG-family-protein
MFQQSNVYQQPNPYAQQNMYQYNTDTYLRYNMYPFEPHYGNQNYYQPFEVSFMNQQQQQQPYMNQSQQEQQSYMNQQQPYMNSQYYMPPPSSPYGNQQAMFYPPKQPYPTMNKQKQQQQPSQFSSFVSQFKNSDGNYDVNKMMNTAGQMMNAMNQVTGIVKQVGGFFGK
>NC_018693.1|WP_000242658.1|742476_742668_-|YppF-family-protein
MVLGDLKQAFSQKKGYYTENVNELLDFARHCYLEGKICISDYRTLIKELEINGATKPTTMTEA
>NC_018693.1|WP_000455491.1|742106_742451_+|YppE-family-protein
MEYEALIQSSEKLMQYNNEANVKKREIIEYDFYKDMKPFVDIVDEELKVWKELAYTWIKEEKPKYIHVQQIDQVYDNLQTNVLQCFVNKGKGKRFFETHQAISYTLQNIVEQCK
>NC_018693.1|WP_001252045.1|741848_742091_+|hypothetical-protein
MAMVQKVDVMKKMDQMLSSLDLLEMNIGIRINHALKDKSEKICNKIEITEMHIEHMENKLVHHEEKGNWVKTFQNIVVSA
>NC_018693.1|WP_043322869.1|740393_741419_+|DUF2515-domain-containing-protein
MFTWNDYEKMKQYRKNMVCTKEEKAIIHTIKKKTEIANMDNISRTQSYQKFYVRNSEIRWSFLASMVSRNAGWNMTDLEGRSYATVLPRLVKKHLFLIYEQANWIIFLDAFPQLLLYEESKRRRIPLFHLLQFFNVSLFMEKEWTFFWEKKDMNRLMTALIINEQNKIQKPVIENSYFKKHVFHTALFKVQDMLHISAVIFPTIEGGMYGFSVYQFETLQKRIELGKKLAWLLFHPTYKRLFYNFALQTTHTGSREDYEYYLRGTRKSYTPALRDVYSLVAHEEITMRDWFCEDSKMNALFLFEEPKDEVNIKEWYRRKREQIYAVSIVNRFVKRIDEFMI
>NC_018693.1|WP_000658722.1|749451_749643_+|hypothetical-protein
MKEIIINTVDVIRGIDSVKEDRLDTVLAESKRILNKVNIRLERIEQRHKEIEDKVMELNALFS
>NC_018693.1|WP_000886367.1|749681_749903_+|hypothetical-protein
MLDLVFITATTVFAMLFVWLLSDTKKDSLNREERLLNHIEKQGEALDRVTDTMEKMDVRLIHIENKVNKDHKE
>NC_018693.1|WP_000343505.1|749926_750388_+|hypothetical-protein
MDEINNQGQQEQVKDVEETVEETQQNEEVVEEKTDSQEEVDVLQEQIDELSQYKPKELTDDEIKIQQKLEAIWQREVSQTLKEEGVEVFADFINVSVDDTEALQSQITKLKEIIGQLELANGYQPTNHKQVDGYSIAKKNKDTKSMIRHKLNF
>NC_018693.1|WP_000887343.1|750409_751291_+|DUF5309-domain-containing-protein
MLDSKKLTVNENIHLTDAIALVAPIATPFMSLLLQKGLYVDSQGKFHTWREKTLDATSDITVDEGVDATNFVQSARAELNNVMEIFYKATSVSGTAQATGKVGDLFAQEIDDRLRELAIGIEKKLIGGVKNDGTSGKRQMDGILKFVDAGNVVNGATLNKITEAEVKSLARKLWDAGNENGEFFALVGADLKDQIDDLYKGNYTYMHPTKDFGLVVHSVETSYGTINFVLDRFMPADKMVAFDINALKVAFLRQPAFEALGKTGDNIKGQVVAEASLEVGSKKAVAVYNLKQA
>NC_018693.1|WP_000022953.1|751397_751571_+|helix-turn-helix-transcriptional-regulator
MSIKDVYIIERRKKKIRLRQLAEYIGCSPSLLSRYETGDCDMDKEKVKKYKEFIDSY
>NC_018693.1|WP_000812303.1|751795_752611_+|hypothetical-protein
MKQNFKEKFPQWVNESGDYTVCLSDDLDSLVGASILKSVNGYEIKHFYDFTNFYSVDGDKRKAIGVDIALEKGMTWDNHVVRLSRYGKVNTLSANPNVIENIDRDNYTKKYAMSTALLMWAFYGLPLPESDEGKMLLLSIDSSYKGHYTGFEAVQNEWLRKLGFEGLIEIQNKYTLKDFANIKKKYNSSMKIELVNGQLQTEMYLEGISKVLGLPIELPICCFKLRKRFQREKVELRNYTIYTKDMIEEKYKKEIFSMALTQKNTISLTFK
>NC_018693.1|WP_000485081.1|752642_752846_+|hypothetical-protein
MFQEKEYFYCYSTNLYEFLRYEKGLKYICTAFHDKTMRRFWQFKKTDELMKALSEYHDNGEKMNLDK
>NC_018693.1|WP_000301968.1|752927_753902_+|hypothetical-protein
MAVYFNKEELKYRLEFNEKENYIAIPNNIFEILSKDEELMSKKAPHVAVAYTYIYYITWLYRYAKYGVMSEELTDVKGVKEVLGISPKNKDFNYVIKKNGVLDRLWLTETKSFTQAPVEWHWDEINNVFDGFTTYEEQQNARHPQDIKELKTMGIEVNVKRRQIKYPIFAMEDREVDGEKFYGTFYQPEHTHAVPFEVFIECMTNKDLGCTAFYIYAYLYSRCGMNGGSIDVSIEKISAVTGVRPTSRDKALDGLKKYGLIKCYASDYIIDKGDLETPPNTYVVVEKAHLFNLKPVPYKKRTVKTLEQHEKQKEMIKEFENFPL
>NC_018693.1|WP_000172731.1|754112_754502_+|hypothetical-protein
MTLKEALKKVTKENRMYFNYKFPDTRFDQTIQPKNEEEFLISVGRKTMNGFRNWEKTPEYANLVALYLQSKMIDDIHIIYKVVREKALTGDEKQVKLLLTLNKEINSIIKAGIELSKVDEEPEDDGLIV
>NC_018693.1|WP_000101607.1|754501_756079_+|bacteriophage-terminase-large-subunit
MARKPTTAEKLTIINENPELWLKNFVKITTNTGEYVPFTINEQQKYFVDEMGHFNIIAKARQIGFSTLSVALCLWMACTRPRTNYLIVSYKQDSATSLFDKLKMMYDDLPHDKFKFPKDDQNNRSQLKLDNGSSITLSVAGGKDVGRGTTYEYILLSEFAFYENQDSILLSAEQALAKSKTSKLVIETTSNGFNSYQKLFMNAYKENSKYKAFFFPFYSSSYAKQFKDDYDEAEAWHKANNEGKRLTKEDLEQDELFLYEQGATLKQLMWRRWKLLDMTLQQFYQEFPATPMESFISSGLNVFDQQKIVERLKYIEKPLLYKDIKMDIPDSIAKYIGKSLMIYELPKQGIKYYAGVDTASGSGGDYSTISILNADGEQVLSFYDNKIPVYEFAKLLDTIGKFYNYAFLTVERNSFGTPILERLRKEYEYMNLYKHKVFNQQLGKKQLQLGYQTTQVTKNIMITDLKEQFELGMILINCQESLEQMQIFIETDGKTGNKKGKDKHDDCVIAMALAIQGIKQNKWYV

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Crispr_ID: NC_018693_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018693_2

2820391-2823746

Orphan

Consensus_repeat	Method
ACNGGNGCTACTGGNCCT	CRT

74 spacers

The CRISPR arrays of NC_018693_2

>merge|NC_018693|2|2820391-2823746|CRT
ACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCTACTGGGCCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGGCCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGGCCTACTGGACCTCGGGGAACCAGGGGCGCTACCGGCGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCTACTGGACCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCTACTGGACCTACGGGGCCTCGGGGTAACACGGGCGCTACCGGCGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACTGGACCTACTGGACCTCGAGGTACCGCGGGCGCTGCCGGCGCTACTGGGCCTACTGGATCTCGAGGTAACACGGGCGGTACCGGCGCTACTGGACCTCCTGGACCTGGAGGTGCACCGGTCGCTACAGGCGCTACTGGACCTACGGGGCCTCGGGGTAACACGGGCGCTACCGGTGCTACTGGGCCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCTACTGGACCTCCTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGGCCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCTACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCTACGGGCCCTACTGGCCCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGGCCTTCTGGACCTCGAGGTAACTCGGGCGCTACCGGCGCTACTGGCCCTACTGGATCTCGAGGTGCCACGGGCGCTACCGGCGCCACTGGACCTACTGGACCTGGAGGTAACACGGGCGCTACCGGTGCTAATGGGCCTACTGGACCTCGTGGTGCCACGGGCGCTACCGGCGCTACTGGACCTACTGGACTTCAAGGTAACACGGGGGCTACCGGTGCCACTGGGCCTACTGGATCTCGAGGTGCCACGGGCGCTACCGGCGCTACTGGGCCTACTGGACCTACTGGACCTGGAGGTAACACGGGCGCTACTGGACCTCCTGGCCCTCGAGGTGACTCGGGCGCTACCGGCGCTACTGGACCTACTGGATCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGGCCTACTGGACCTCGAGGTGCCACGGGCGCTACCGGTGCTACTGGGCCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGGCCTACTGGACCTCGGGGGGGCACGGGCGCTACTGGACCTCCTGGCCCTCGGGGTAACCCGGGCGCAACCGGCGCTACTGGACCTGCTGGATCTCGAGGTAACACGGGCGGTACCGGCGCTACTGGACCTGCTGGACCTCGGGGTGACACGGGCGCTACTGGACCTACGGGGCCTCGGGGTAACACGGGCGCTACCGGTGCTACTGGGCCTACTGGATCTCGAGGTGCCACGGGCGCTACCGGCGCCACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGTGCTACTGGGCCTACTGGACCTCGAGGTAACACGGGCGCTACTGGACCTACTGGTCCTCCGGGTAACACCGGCGCTACTGGACCTCCTGGCCCTCGGGGTAACCCGGGCGCAACCGGCGCTACTGGACCTGCCGGACCTCGGGGTAACACGGCCGCTACCGGTGCTACTGGGCCTTCTGGACCTCGAGGTAACGCGGGCGCTCCCGGCGCTACTGGCCCTACTGGGCCTCGTGGTAACACGGGCGCTACAGGCGCTACTGGACCTACAGGACCTCGAGGAACCACGGGCGCTACCGGCGCCACTGGCCCTACTGGACCTGGAGGTAACACGGGCGCTGCCGGTGCTACTGGGCCTTCTGGACCTCGGGGAACCAGGGGCGCTACCGGCGCTACTGGAACTACTGGACCTCGAGGTGACACGGGCGCGACCGGCGCTACTGGACCTGCCGGACCTCGGGGTAACACGGGCGCTGCCGGCGCTACTGGACCTACTGCACCTCGGGGTAACACCGGCGCTGCTGGACCTGCTGGACCTCGGGGTGACACGGGCGCTACTGGACCTACGGGGCCTCGGGGTAACACGGGCGCTACTGGTCCTACTGGACCTCGAGGCAACACGGGCGCTACTGGTCCTACTGGACCTCGAGGGAACACGGGCGCTGCCGGTGCTACTGGGCCTTCTGGACCTCGGGGTAACACGGGCGCTACAGGCGCTACTGGACCTACAGGACCTCGAGGAACCACGGGCGCTACCGGTGCTACTGGCCCTCCTGGCCCTCGGGGAAACACGGGCGCTACCGGCCCTACTGGACCTACGGGACCTCGAGGTAACACGCGCGCTACCGGTGCTACTGGCCCTCCTGGCCCTCGGGGTAACCCGGGGGCCACTGGCGCTACTGGACCTCAAGGTGCTCAAGGTAACACTGGTGCTACTGGTGCCACTGGACCTCAAGGGGTTCAAGGTAACACGGGGGCTACCGGCGCTACTGGGCCTTCTGGACCTCGGGGTAACGCGGGCGCTGCCGGTGCTACTGGGCCTTCTGGACCTCGAGGTAACTCGGGCGCTACCGGCGCTACTGGGCCTACTGGACCTACTGGGTCTCGGGGTAACACGGGCGCTGCCGGCGCTACTGGGCCTACTGGACCTCGGGGTACCTCGGGCGCTACCGGCGCTACTGGACCTACTGGACCTCAAGGTAACACGGGGGCTACTGGCGCTACTGGACCTCAAGGTGCTCAAGGTAACACTGGTGCTACCGGTGCCACTGGACCTACTGGACCTCGGGGTAACACGGGTGCTACTGGTGCCACTGGACCTCAAGGCGCTCAAGGTAACACGGGGGCTACTGGTGCCACTGGGGCTACCGGACCTCAAGGGGTTCAAGGTAACACGGGGGCTACTGGTGCCACTGGACCTCAAGGCGCTCAAGGTAACACAGGCGCTACAGGCGCTACTGGACCTGCTGGACCTCGGGGTAACACTGGTGCTACAGGCGCTACTGGACCTCAAGGGGTTCAAGGTAACACGGGGGCTACTGGTGCTACCGGGCCACTGGACGTCAAGGTAACACGGGGGCTACTGGTGCC

>NC_018693|2|1|2820391-2823746|CRT
ACTGGACCTACTGGACCT	CGAGGTAACACGGGCGCT
ACCGGCGCTACTGGGCCT	ACTGGACCTCGAGGTAACACGGGCGCT
ACCGGCGCTACTGGACCT	ACTGGACCTCGAGGTAACACGGGCGCT
ACCGGTGCTACTGGGCCT	ACTGGACCTCGAGGTAACACGGGCGCT
ACCGGCGCTACTGGACCT	ACTGGACCTCGAGGTAACACGGGCGCT
ACCGGTGCTACTGGGCCT	ACTGGACCTCGGGGAACCAGGGGCGCT
ACCGGCGCTACTGGACCT	ACTGGACCTCGAGGTAACACGGGCGCT
ACCGGCGCTACTGGACCT	ACTGGACCTCGAGGTAACACGGGCGCT
ACCGGCGCTACTGGACCT	ACTGGACCTACTGGACCTCGAGGTAAC
ACGGGCGCTACTGGACCT	ACTGGACCTCGAGGTAACACGGGCGCT
ACCGGCGCTACTGGACCT	ACTGGACCTCGAGGTAACACGGGCGCT
ACCGGCGCTACTGGACCT	ACGGGGCCTCGGGGTAACACGGGCGCT
ACCGGCGCTACTGGACCT	ACTGGACCTCGAGGTAAC
ACGGGCGCTACTGGACCT	ACTGGACCTCGAGGTACC
GCGGGCGCTGCCGGCGCT	ACTGGGCCTACTGGATCTCGAGGTAAC
ACGGGCGGTACCGGCGCT	ACTGGACCTCCTGGACCTGGAGGTGCA
CCGGTCGCTACAGGCGCT	ACTGGACCTACGGGGCCTCGGGGTAAC
ACGGGCGCTACCGGTGCT	ACTGGGCCTACTGGACCTCGAGGTAAC
ACGGGCGCTACCGGCGCT	ACTGGACCTCCTGGACCTCGAGGTAAC
ACGGGCGCTACCGGTGCT	ACTGGGCCTACTGGACCTCGAGGTAAC
ACGGGCGCTACCGGCGCT	ACTGGACCTACTGGACCTCGAGGTAACACGGGCGCTACCGGCGCT
ACGGGCCCTACTGGCCCT	CGAGGTAACACGGGCGCTACCGGTGCT
ACTGGGCCTTCTGGACCT	CGAGGTAACTCGGGCGCTACCGGCGCT
ACTGGCCCTACTGGATCT	CGAGGTGCCACGGGCGCTACCGGCGCC
ACTGGACCTACTGGACCT	GGAGGTAACACGGGCGCTACCGGTGCT
AATGGGCCTACTGGACCT	CGTGGTGCCACGGGCGCTACCGGCGCT
ACTGGACCTACTGGACTT	CAAGGTAACACGGGGGCTACCGGTGCC
ACTGGGCCTACTGGATCT	CGAGGTGCCACGGGCGCTACCGGCGCTACTGGGCCT
ACTGGACCTACTGGACCT	GGAGGTAACACGGGCGCT
ACTGGACCTCCTGGCCCT	CGAGGTGACTCGGGCGCTACCGGCGCT
ACTGGACCTACTGGATCT	CGAGGTAACACGGGCGCTACCGGTGCT
ACTGGGCCTACTGGACCT	CGAGGTGCCACGGGCGCTACCGGTGCT
ACTGGGCCTACTGGACCT	CGAGGTAACACGGGCGCTACCGGTGCTACTGGGCCTACTGGACCTCGGGGGGGC
ACGGGCGCTACTGGACCT	CCTGGCCCTCGGGGTAACCCGGGCGCA
ACCGGCGCTACTGGACCT	GCTGGATCTCGAGGTAACACGGGCGGT
ACCGGCGCTACTGGACCT	GCTGGACCTCGGGGTGAC
ACGGGCGCTACTGGACCT	ACGGGGCCTCGGGGTAACACGGGCGCT
ACCGGTGCTACTGGGCCT	ACTGGATCTCGAGGTGCCACGGGCGCT
ACCGGCGCCACTGGACCT	ACTGGACCTCGAGGTAACACGGGCGCT
ACCGGTGCTACTGGGCCT	ACTGGACCTCGAGGTAACACGGGCGCTACTGGACCTACTGGTCCTCCGGGTAAC
ACCGGCGCTACTGGACCT	CCTGGCCCTCGGGGTAACCCGGGCGCA
ACCGGCGCTACTGGACCT	GCCGGACCTCGGGGTAACACGGCCGCT
ACCGGTGCTACTGGGCCT	TCTGGACCTCGAGGTAACGCGGGCGCT
CCCGGCGCTACTGGCCCT	ACTGGGCCTCGTGGTAACACGGGCGCT
ACAGGCGCTACTGGACCT	ACAGGACCTCGAGGAACCACGGGCGCTACCGGCGCC
ACTGGCCCTACTGGACCT	GGAGGTAACACGGGCGCTGCCGGTGCT
ACTGGGCCTTCTGGACCT	CGGGGAACCAGGGGCGCTACCGGCGCT
ACTGGAACTACTGGACCT	CGAGGTGACACGGGCGCG
ACCGGCGCTACTGGACCT	GCCGGACCTCGGGGTAACACGGGCGCT
GCCGGCGCTACTGGACCT	ACTGCACCTCGGGGTAAC
ACCGGCGCTGCTGGACCT	GCTGGACCTCGGGGTGAC
ACGGGCGCTACTGGACCT	ACGGGGCCTCGGGGTAAC
ACGGGCGCTACTGGTCCT	ACTGGACCTCGAGGCAAC
ACGGGCGCTACTGGTCCT	ACTGGACCTCGAGGGAAC
ACGGGCGCTGCCGGTGCT	ACTGGGCCTTCTGGACCTCGGGGTAAC
ACGGGCGCTACAGGCGCT	ACTGGACCTACAGGACCTCGAGGAACC
ACGGGCGCTACCGGTGCT	ACTGGCCCTCCTGGCCCTCGGGGAAAC
ACGGGCGCTACCGGCCCT	ACTGGACCTACGGGACCTCGAGGTAAC
ACGCGCGCTACCGGTGCT	ACTGGCCCTCCTGGCCCTCGGGGTAACCCGGGGGCC
ACTGGCGCTACTGGACCT	CAAGGTGCTCAAGGTAACACTGGTGCT
ACTGGTGCCACTGGACCT	CAAGGGGTTCAAGGTAACACGGGGGCT
ACCGGCGCTACTGGGCCT	TCTGGACCTCGGGGTAACGCGGGCGCT
GCCGGTGCTACTGGGCCT	TCTGGACCTCGAGGTAACTCGGGCGCT
ACCGGCGCTACTGGGCCT	ACTGGACCTACTGGGTCTCGGGGTAACACGGGCGCT
GCCGGCGCTACTGGGCCT	ACTGGACCTCGGGGTACCTCGGGCGCT
ACCGGCGCTACTGGACCT	ACTGGACCTCAAGGTAACACGGGGGCT
ACTGGCGCTACTGGACCT	CAAGGTGCTCAAGGTAACACTGGTGCTACCGGTGCC
ACTGGACCTACTGGACCT	CGGGGTAACACGGGTGCT
ACTGGTGCCACTGGACCT	CAAGGCGCTCAAGGTAACACGGGGGCT
ACTGGTGCCACTGGGGCT	ACCGGACCTCAAGGGGTTCAAGGTAACACGGGGGCT
ACTGGTGCCACTGGACCT	CAAGGCGCTCAAGGTAACACAGGCGCT
ACAGGCGCTACTGGACCT	GCTGGACCTCGGGGTAACACTGGTGCT
ACAGGCGCTACTGGACCT	CAAGGGGTTCAAGGTAAC
ACGGGGGCTACTGGTGCT	ACCGGGCCACTGGACGTCAAGGTAAC
ACGGGGGCTACTGGTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018693.1\|WP_000181509.1\|2817443_2817581_+\|hypothetical-protein	unknown	unknown	unknown
NC_018693.1\|WP_000813896.1\|2825726_2825951_-\|RNA-chaperone-Hfq	unknown	unknown	gnl\|CDD\|179001
NC_018693.1\|WP_000323601.1\|2810518_2811181_-\|CpsD/CapB-family-tyrosine-protein-kinase	unknown	unknown	gnl\|CDD\|349772
NC_018693.1\|WP_000391424.1\|2815352_2816627_-\|GTPase-HflX	unknown	unknown	gnl\|CDD\|274455
NC_018693.1\|WP_001179085.1\|2832384_2833548_-\|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|341466
NC_018693.1\|WP_000504365.1\|2825972_2826926_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NC_018693.1\|WP_001031074.1\|2811129_2811870_-\|LPS-biosynthesis-protein	unknown	unknown	gnl\|CDD\|226453
NC_018693.1\|WP_000450336.1\|2818834_2819800_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NC_018693.1\|WP_000640840.1\|2830563_2831475_-\|1-phosphofructokinase	unknown	unknown	gnl\|CDD\|238570
NC_018693.1\|WP_000734606.1\|2827415_2828345_-\|3D-domain-containing-protein	unknown	unknown	gnl\|CDD\|226112
NC_018693.1\|WP_000438193.1\|2817613_2818570_-\|stage-V-sporulation-protein-K	unknown	unknown	gnl\|CDD\|163057
NC_018693.1\|WP_000135333.1\|2812140_2813475_-\|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl\|CDD\|273198
NC_018693.1\|WP_000957289.1\|2831471_2832224_-\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NC_018693.1\|WP_000814417.1\|2827107_2827353_+\|hypothetical-protein	unknown	unknown	unknown
NC_018693.1\|WP_000312263.1\|2816719_2817343_+\|trimeric-intracellular-cation-channel-family-protein	unknown	unknown	gnl\|CDD\|225415
NC_018693.1\|WP_000460315.1\|2814088_2815360_-\|methionine-gamma-lyase-family-protein	unknown	unknown	gnl\|CDD\|311036
NC_018693.1\|WP_087991508.1\|2824296_2825651_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_018693.1\|WP_000704650.1\|2828693_2830550_-\|PTS-fructose-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|236740
NC_018693.1\|WP_000228316.1\|2833665_2834208_-\|DUF420-domain-containing-protein	unknown	unknown	gnl\|CDD\|225204
NC_018693.1\|WP_000656783.1\|2813523_2813913_-\|transcriptional-repressor-GlnR	unknown	unknown	gnl\|CDD\|133380

Protein	Function_ID	Function_description	E-value
NC_018693.1\|WP_000704650.1\|2828693_2830550_-\|PTS-fructose-transporter-subunit-IIABC	gnl\|CDD\|236740	PRK10712, PRK10712, PTS system fructose-specific transporter subunits IIBC; Provisional.	2.21616e-144
NC_018693.1\|WP_000813896.1\|2825726_2825951_-\|RNA-chaperone-Hfq	gnl\|CDD\|179001	PRK00395, hfq, RNA-binding protein Hfq; Provisional.	3.4363e-41
NC_018693.1\|WP_000323601.1\|2810518_2811181_-\|CpsD/CapB-family-tyrosine-protein-kinase	gnl\|CDD\|349772	cd05387, BY-kinase, bacterial tyrosine-kinase. Bacterial tyrosine (BY)-kinases catalyze the autophosphorylation on a C-terminal tyrosine cluster and also phosphorylate endogenous protein substrates by using ATP as phosphoryl donor. Besides their capacity to function as tyrosine kinase, most of these proteins are also involved in the production and transport of exopolysaccharides. BY-kinases are involved in a number of physiological processes ranging from stress resistance to pathogenicity.	3.45117e-73
NC_018693.1\|WP_000391424.1\|2815352_2816627_-\|GTPase-HflX	gnl\|CDD\|274455	TIGR03156, GTP_HflX, GTP-binding protein HflX. This protein family is one of a number of homologous small, well-conserved GTP-binding proteins with pleiotropic effects. Bacterial members are designated HflX, following the naming convention in Escherichia coli where HflX is encoded immediately downstream of the RNA chaperone Hfq, and immediately upstream of HflKC, a membrane-associated protease pair with an important housekeeping function. Over large numbers of other bacterial genomes, the pairing with hfq is more significant than with hflK and hlfC. The gene from Homo sapiens in this family has been named PGPL (pseudoautosomal GTP-binding protein-like). [Unknown function, General].	0
NC_018693.1\|WP_001179085.1\|2832384_2833548_-\|iron-containing-alcohol-dehydrogenase	gnl\|CDD\|341466	cd08187, BDH, Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. The butanol dehydrogenase (BDH) is involved in the final step of the butanol formation pathway in anaerobic micro-organism. Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process. Activity in the reverse direction is 50-fold lower than that in the forward direction. The NADH-BDH has higher activity with longer chained aldehydes and is inhibited by metabolites containing an adenine moiety. This protein family belongs to the so-called iron-containing alcohol dehydrogenase superfamily. Since members of this superfamily use different divalent ions, preferentially iron or zinc, it has been suggested to be renamed to family III metal-dependent polyol dehydrogenases. This family also includes E. coli YqhD enzyme, an NADP-dependent dehydrogenase whose activity measurements with several alcohols demonstrate preference for alcohols longer than C3. The active site of YqhD contains a Zn metal, and a modified NADPH cofactor bearing OH groups on the saturated C5 and C6 atoms, possibly due to oxygen stress on the enzyme, which would functionally work under anaerobic conditions.	0
NC_018693.1\|WP_000504365.1\|2825972_2826926_-\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	2.08152e-169
NC_018693.1\|WP_001031074.1\|2811129_2811870_-\|LPS-biosynthesis-protein	gnl\|CDD\|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	1.95573e-42
NC_018693.1\|WP_000450336.1\|2818834_2819800_+\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	7.08854e-12
NC_018693.1\|WP_000640840.1\|2830563_2831475_-\|1-phosphofructokinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	1.84261e-140
NC_018693.1\|WP_000734606.1\|2827415_2828345_-\|3D-domain-containing-protein	gnl\|CDD\|226112	COG3584, COG3584, Uncharacterized protein conserved in bacteria [Function unknown].	6.79259e-38
NC_018693.1\|WP_000438193.1\|2817613_2818570_-\|stage-V-sporulation-protein-K	gnl\|CDD\|163057	TIGR02881, Stage_V_sporulation_protein_K, stage V sporulation protein K. Members of this protein family are the stage V sporulation protein K (SpoVK), a close homolog of the Rubisco expression protein CbbX (TIGR02880) and a members of the ATPase family associated with various cellular activities (pfam00004). Members are strictly limited to bacterial endospore-forming species, but are not universal in this group and are missing from the Clostridium group. [Cellular processes, Sporulation and germination].	1.47829e-155
NC_018693.1\|WP_000135333.1\|2812140_2813475_-\|type-I-glutamate--ammonia-ligase	gnl\|CDD\|273198	TIGR00653, Glutamine_synthetase, glutamine synthetase, type I. Alternate name: glutamate--ammonia ligase. This model represents the dodecameric form, which can be subdivided into 1-alpha and 1-beta forms. The phylogeny of the 1-alpha and 1-beta forms appears polyphyletic. E. coli, Synechocystis PCC6803, Aquifex aeolicus, and the crenarcheon Sulfolobus acidocaldarius have form 1-beta, while Bacillus subtilis, Thermotoga maritima, and various euryarchaea has form 1-alpha. The 1-beta dodecamer from the crenarcheon Sulfolobus acidocaldarius differs from that in E. coli in that it is not regulated by adenylylation. [Amino acid biosynthesis, Glutamate family].	0
NC_018693.1\|WP_000957289.1\|2831471_2832224_-\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	2.03609e-80
NC_018693.1\|WP_000312263.1\|2816719_2817343_+\|trimeric-intracellular-cation-channel-family-protein	gnl\|CDD\|225415	COG2860, COG2860, Predicted membrane protein [Function unknown].	8.25063e-61
NC_018693.1\|WP_000460315.1\|2814088_2815360_-\|methionine-gamma-lyase-family-protein	gnl\|CDD\|311036	pfam06838, Met_gamma_lyase, Methionine gamma-lyase. This is a putative pyridoxal 5'-phosphate-dependent methionine gamma-lyase enzyme involved in methionine catabolism.	0
NC_018693.1\|WP_087991508.1\|2824296_2825651_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.53388e-54
NC_018693.1\|WP_000228316.1\|2833665_2834208_-\|DUF420-domain-containing-protein	gnl\|CDD\|225204	COG2322, COG2322, Predicted membrane protein [Function unknown].	1.75148e-56
NC_018693.1\|WP_000656783.1\|2813523_2813913_-\|transcriptional-repressor-GlnR	gnl\|CDD\|133380	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators. Helix-turn-helix (HTH) transcription regulator GlnR and related proteins, N-terminal domain. The GlnR and TnrA (also known as ScgR) proteins have been shown to regulate expression of glutamine synthetase as well as several genes involved in nitrogen metabolism. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	1.14369e-23

>NC_018693.1|WP_000450336.1|2818834_2819800_+|site-specific-integrase
METTEFHDTIQAFSIFLLNKGRKTSTIKRYVYDIEDFGHWLEKNKKLPSSNIWATLCTKDYEDYFSELKTNRNYSEKTMHRVFIVLNRMNHFLNIPNPLKNMEISIQPDRALRNEDFISSNEEKKLKRIVTSLEGLSEKQRPVRPLLMDRNITILNLLIDYGLSLQELTALTMYHVHFETNTLSIPATAGVERTITLTKEDKKQLYTYYKSIPEPVRPKYHSNDPLFVAFDFNRGTYRWVYENDSPKGLTEIAIQKMIRLEVARANLRKGISGQHFRNTYILNLIKKETPESEIIKLAGFKSKVSLKRYYKYAENRKNALL
>NC_018693.1|WP_000438193.1|2817613_2818570_-|stage-V-sporulation-protein-K
MEQSMRKKNNNQINIVLNHRKKISLPASENKTEISNETTIKHEMLQRIEEEMGKLVGMDDIKKIIKEIYAWIYVNKKRQEMGLKSEKQVLHMLFKGNPGTGKTTVARMIGKLLFEMNILSKGHLVEAERADLVGEYIGHTAQKTRDLIKKAMGGILFIDEAYSLARGGEKDFGKEAIDTLVKHMEDKQHGFVLILAGYSREMNHFLSLNPGLQSRFPFIIEFADYSVNQLLEIGKRMYEEREYQLSKEAEWKFRDHLHAVKYSSQITSFSNGRYVRNIVEKSIRTQAMRLLQEDTYDKYDLIGISSVDLMLEEETHST
>NC_018693.1|WP_000181509.1|2817443_2817581_+|hypothetical-protein
MTNHVNKGAQKSSVNQFGHDSNSAHEKSAKMERFHKSHQEKEKKE
>NC_018693.1|WP_000312263.1|2816719_2817343_+|trimeric-intracellular-cation-channel-family-protein
MAWEIFSIIGTIAFALSGAIVAMEEDYDIFGVYILGMATAFGGGALRNLLIGYPIVAFWQQDMLFQIALLSMTIIFLFPNKLIKHWKKWENITDAIGLSAFAVQGALYAQKLNLPISATIVAAVLTGIGGGIIRDLLARRKPLVLRAEVYAFWTILAGFLIGAQIIVSDWALYTLFILIVCFRMLSIHYKWHLPHRRIDTNERSMHK
>NC_018693.1|WP_000391424.1|2815352_2816627_-|GTPase-HflX
MEEKEKVILVGCQLQQDDDEQFMHSMKELASLAKTARAKVLVSTTQKRPKFHPVTYIGKGKLEELTMLTEELEPDVIIFNNELTPSQIRNLSSVLDARVIDRTQLILDIFAQRAKSREGKLQVELAQLQYTMPRLMGQGLSLSRLGGGIGTRGPGETKLETDRRHIRSRIDEIKKQLAVVVEHRKRYRERRKDNKVFQVSLIGYTNAGKSTLFNRLTEADTFEENLLFATLDPTTRKMPLPSGYTVLLTDTVGFIQDLPTSLIAAFRSTLEEAGEADVILHVVDSADPNYVGHEKTVKKLLSELEINHIPIITLYNKKDALHQNFIPFPKSDFLMTSAFEESDLLHIKEAIETKMKEEMDPYQVEIPPSEGKLLTLLKTETLLTKMEFLEDKFVYNCTGYIFAYSPYNGQLKRFLVEEGENDNV
>NC_018693.1|WP_000460315.1|2814088_2815360_-|methionine-gamma-lyase-family-protein
MFDRLKNGEKMAPIVKEVESQITEVHKRADEVIESNQFRVLESFRKHKISDSHFIPTTGYGYDDIGRDTLEKVYADVFGAEAGLVRPQIISGTHAISTALFGILRPGDELLYITGKPYDTLEEIVGVRGKGVGSFKEYNIGYNAVSLTEEGLVDFEAVAAAIHSNTKMIGIQRSKGYATRPSFTISQIKEMISFVKEIKPDVVVFVDNCYGEFIEEQEPCHVGADLMAGSLIKNPGGGIVKTGGYIVGKEQYVEACAYRLTSPGIGAEAGASLYSLQEMYQGFFLAPHVAGQALKGAIFTAAFLEKLGMNTSPAWNAPRTDLIQSVQFDDKDRMIAFCQAIQYASPINSHFTPYANYMPGYEDDVIMAAGTFIQGASIELSADGPIRPPYVAYVQGGLTYSHVKIAICSAIDALIEKKLLTIS
>NC_018693.1|WP_000656783.1|2813523_2813913_-|transcriptional-repressor-GlnR
MKEDRRSAPLFPIGIVMDLTQLSARQIRYYEEHNLVSPTRTKGNRRLFSFNDVDKLLEIKDLLDQGLNMAGIKQVLLMKENQTEAVKVKEETKEISKTELRKILRDELQHTGRFNRTSLRQGDISRFFH
>NC_018693.1|WP_000135333.1|2812140_2813475_-|type-I-glutamate--ammonia-ligase
MARYTKEDIFRLAKEENVKYIRLQFTDLLGVIKNVEIPVSQLTKALDNKMMFDGSSIEGFVRIEESDMYLYPDLDTWVIFPWTAEKGKVARLICDIYTADGAPFDGDPRNNLKRVLKEMEALGFSDFNLGPEPEFFLFKVDEKGNPTLELNDNGGYFDLAPMDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYANAIRSCDDIQTFKLVVKTIARKHGLHATFMPKPLYGVNGSGMHCNLSLFKNGENVFFDQNGDLQLSDDARHFIAGILKHAPAFTAVANPTVNSYKRLVPGYEAPCYVAWSAQNRSPLVRIPASRGISTRVEVRSVDPAANPYLVMATLLAAGLDGIKNKLTPPAAVDRNIYVMTKEEREEAGIVDLPATLAQALVTLQSNEVVCSALGEHLLEHFIEAKEIEWDIFRTQVHQWERDQYMSLY
>NC_018693.1|WP_001031074.1|2811129_2811870_-|LPS-biosynthesis-protein
MNKEINLKNLFTVIWKRVWILLLFTTLTTVGGAMYSMYMKTPLYASSARVIVQANAETMNTLKAMVNEPVILEKVAAELNINRSAGALSGQISTESVQGSQIMRINVVDIDPVLAHKIANTTAAVYKKEVANILNFNNVSILPEDPVQKHSMPININHFKTILIAFSVGMVLSIGFIFLLDSFDDRIKSERRIEQLLDVPVLGGISKMNRKNTEDKFSEKNTVVLGDGTEWPTKIDEKQIKLKEKV
>NC_018693.1|WP_000323601.1|2810518_2811181_-|CpsD/CapB-family-tyrosine-protein-kinase
MAYKNRRKTNKVKGESIIAYTAPRSKISEQYRSLRTNLQLSSSIHKSRTIVITSPRYGEGKSTITVNLAVSIAQKGEKVLIIDANLRTPTIQEMFGVENTVGLTDILNGKTNLEGAVKKTEMERLDVLTSGPVPFNPSEVLGSDEMDMLIQKAMERYDIILFDSSPVLEVTDTSVLVDKCEGVLLVIRYNRTVSEDALETKRALSFTKSRILGAILNGKV
>NC_018693.1|WP_087991508.1|2824296_2825651_+|IS3-family-transposase
MVKFTADEKIHIVQRYLNGNESYREISKAVGIRDTVILNWVNQYKQNGVEAFLKRYTNYTQQFKLDVLNFMIENGTSLFETAAIFNIPAPSTIIVWKKQFETQGIAALQSKKKGRPSMEKDSNKQSKQTPVEGSVEALEARIQQLEMENEYFKKVECLSSKQGKITKQDKAQVVYELRHKYSAKALVALANIPRSTYYDLVKKMNRPDLDADLKAEIKAIYEENEGRYGYRRIRDELTNRGQKVNHKKVQRIMKELGLKCVVRMKKYKSYKGKVGKTAPNILARNFHADAPNQKWVTDITEFKLFGEKLYISPVLDLYNGEIITYTIGSRPTYSLVSEMLETALERLPENHQLLMHSDQGWHYQMKQYARTLESRGIVQSMSRKGNYYDNTVMENFFGIMKSEFLYIKEFESVDHFKIELEKYVDYYNTKRIKAKLKMSPVQYRTHLDQAA
>NC_018693.1|WP_000813896.1|2825726_2825951_-|RNA-chaperone-Hfq
MKQSINIQDQFLNQLRKENTFVTLYLLNGFQLRGLIKGFDNFTVLLETEGKQQLIYKHAISTFVPQKNVSIELE
>NC_018693.1|WP_000504365.1|2825972_2826926_-|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MGEMQREKVAVIIGPTAVGKTKLSIDLAKALNGEIISGDSMQIYRTMDIGTAKVTKEEMDGIPHYMVDIKDPEDSFSVAEFQERVRKHIREITERGKLPIIVGGTGLYIQSVLFDYQFTDDAGDAIYREQMEKLAQERGVEYVHEKLQEVDPESAERIHANNVRRVIRALEIFHTTGEKMSDQLEKQENELLYDVSLIGLTMDREMLYDRINLRVDLMMEQGLLEEVEGLYNRGIRDCQSIQAIGYKEVYDYFENRVSLEEAVSQLKTNSRRYAKRQLTWFRNKMDVTWFDVTDGEKTSEILRYIEGKLQLKSNNSK
>NC_018693.1|WP_000814417.1|2827107_2827353_+|hypothetical-protein
MKQSTINFSSLTKDLILATATKEQNCSQEELYFALNCLLRSFHSMLQETTLHPENKNTEYMQTQFCSAYKILTGTTIYPFQ
>NC_018693.1|WP_000734606.1|2827415_2828345_-|3D-domain-containing-protein
MKKLLGIATAAVFGLGIFAGSAKAETIVTTDVLNVRENPNVESKLVGKMLSGNKLDVINTENGWSKIKLDGKEAFVSAEFTKSTYYVTANVLNIRAGANTDSEILGKFNKNDLIETTNQVQNEWLQFDYNGKVAYVHVPFLTGEAPVIEKKEVVTQEEPARVNPSVKNNTAVKSKESVKNVESSKPVAKEKPAAKPVKKSAETNAPAGGREITVEATAYTANPSENGTYGGRVLTAMGHDLTANPNMKVIAVDPKVIPLGSKVWVEGYGEAIAGDTGGAIKGNRIDVLVGSDGSANSWGRKSVKVKVIQ
>NC_018693.1|WP_000704650.1|2828693_2830550_-|PTS-fructose-transporter-subunit-IIABC
MKITELLKRDTVIMNLTASNKEAVIDELVEKLSGANRLNSKTEFKEAILKRESQSTTGIGEGIAIPHAKTKAVKQPAICFGRSVSGINYESLDGQPAHLFFMIAASEGANNTHLETLSRLSTLLMDEGFRKQLLEAKDEEELLRLFDEKENEKEEEVEVAKPEGDEPYVLAVTACPTGIAHTYMAADSLKAKAAELGIAIKVETNGSTGIKNGLTKEDIERATAIIVAADKQVEMNRFAGKHVIQVPVADGIRKTEKLLNRAVKQDAPIFKGVKENGKSESIEKEKGLGIYKHLMSGVSNMLPFVVGGGILIALAFSFGGIKAEGPLAELFMSIGGGKTGAFLFLVPILAGFIASSIADRPGFMPGVVGGFLAAHANAGFLGGLIAGFLAGYVVLGLKRLFSGLPAQLEGIKPVLLYPVFGLLITGVVMQKVVNPPVVALNEMLTGWLNGLNGTNAILLGLILGGMMAIDMGGPINKAAFTFGIAAIEAQNFGVHSAVMAGGMVPPLAIAFATTFFKTKFTEAERKSGLTNYIMGASFITEGAIPFAAADPIRVIVSCVVGSSIAGALSMLFQITLPAPHGGLFVIALVNKPLLYIFSILVGTVISALMMGIWKKKVK
>NC_018693.1|WP_000640840.1|2830563_2831475_-|1-phosphofructokinase
MIYTVTLNPSIDYVVQVNSFDLGTVNRAEKDMKFPGGKGINVSRVLHRLGVGNVALGFTGGFTGQFIQDVLHDEGVTTNFVQVDEDTRINVKIKGEEETELNGQGPIVTKEQFGQLMKKIESMQREDCVVLAGSIPASIQNTFYESIAALGAEKGIRVVVDASGSALQHVIKNKPFLIKPNHHELGELFGVELSTVEEILPYGRKLVEQGVENVIVSMAGDGALLFTAEGIYEATVPKGVVINSVGAGDSLVAGFVGKYEQTKEIEKAFQYGVATGSATAFSADLCKKEKVEELLSQVIVVKR
>NC_018693.1|WP_000957289.1|2831471_2832224_-|DeoR/GlpR-transcriptional-regulator
MLTPERHQMILQLVKEQKVVKLQQLVERTESSESTIRRDLAQLEKQRLLKRVHGGASVLTAKGQEPTMIEKSSKNIQIKHQIAKYAATIVEQGDCIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQKYRFDKCFLGANGVHEQFGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEDANIITNHLEIDLEKYKRQTNVIEADKQ
>NC_018693.1|WP_001179085.1|2832384_2833548_-|iron-containing-alcohol-dehydrogenase
MQNFVFRNPTKLIFGKGQLEQLKTEIPQFGKKVLLVYGGGSIKRNGIYDNVISILKDINAEVFELTGVEPNPRVSTVKKGIQICKENGVEFILAVGGGSVIDCTKAIAAGSKYDGDVWDIVTKKAFASEALPFGTVLTLAATGSEMNAGSVITNWETNEKYGWGSPVTFPQFSILDPVHTASVPKDQTIYGMVDIMSHVLEQYFHHGTNTELQDRYCESVLRTVIETAPKLLSDLENYEHRETILYCGTMALNGILAMGVKGDWATHNIEHAVSAVHDIPHGGGLAILFPNWMKHVIDENVSRFKQFAIRVFDIETDGKTDKEVALEGIEALRQFWTSIEAPVALSDYTIGENEIDLMADKAMAYGEFGNFKKLNKDDVLSIYKASL
>NC_018693.1|WP_000228316.1|2833665_2834208_-|DUF420-domain-containing-protein
MVDQSTNQKSYAPIVITLSVIVNAIILFLFFGPVGYEGEVHFDVTILPMLNAIFNSFTFVFLLAALYSIIKKNVKMHRGFILAAFTTTLLFCVSYLSYHYLAPATHFGGEGFIKYVYFIILITHIILAAIIVPLALFALVFGFTNQLTRHRKIVRWTMPIWLYVSLSGVIVYLMISPYYQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018693_2	2.60\|2823064\|27\|NC_018693\|CRT	2823064-2823090	27	MN101228	Klebsiella phage KPN4, complete genome	27715-27741	2	0.926
NC_018693_2	2.12\|2820895\|27\|NC_018693\|CRT	2820895-2820921	27	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	224469-224495	3	0.889
NC_018693_2	2.37\|2822038\|27\|NC_018693\|CRT	2822038-2822064	27	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	224469-224495	3	0.889
NC_018693_2	2.66\|2823343\|27\|NC_018693\|CRT	2823343-2823369	27	MT380195	Klebsiella phage KP_LZD_B01, complete genome	78581-78607	3	0.889
NC_018693_2	2.66\|2823343\|27\|NC_018693\|CRT	2823343-2823369	27	KX845404	Klebsiella phage vB_Kpn_IME260, complete genome	83086-83112	3	0.889
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	AP013411	Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C108A-MedDCM-OCT-S29-C43	29569-29595	4	0.852
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	AP013669	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C108A-MedDCM-OCT-S25-C43, * SEQUENCING IN PROGRESS *	3910-3936	4	0.852
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	JQ691611	Cronobacter phage CR9, complete genome	9688-9714	4	0.852
NC_018693_2	2.16\|2821057\|27\|NC_018693\|CRT	2821057-2821083	27	HQ632825	Prochlorococcus phage P-SSM5 genomic sequence	61662-61688	4	0.852
NC_018693_2	2.16\|2821057\|27\|NC_018693\|CRT	2821057-2821083	27	AY939844	Prochlorococcus phage P-SSM2, complete genome	25294-25320	4	0.852
NC_018693_2	2.22\|2821345\|27\|NC_018693\|CRT	2821345-2821371	27	KU682439	Stenotrophomonas phage vB_SmaS-DLP_6, complete genome	61554-61580	4	0.852
NC_018693_2	2.23\|2821390\|27\|NC_018693\|CRT	2821390-2821416	27	NZ_CP018048	Pseudomonas aeruginosa strain DN1 plasmid unnamed1, complete sequence	215222-215248	4	0.852
NC_018693_2	2.24\|2821435\|27\|NC_018693\|CRT	2821435-2821461	27	MN204498	Streptomyces phage Saftant, complete genome	18538-18564	4	0.852
NC_018693_2	2.24\|2821435\|27\|NC_018693\|CRT	2821435-2821461	27	NZ_CP015065	Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence	245-271	4	0.852
NC_018693_2	2.26\|2821525\|27\|NC_018693\|CRT	2821525-2821551	27	MN204498	Streptomyces phage Saftant, complete genome	18538-18564	4	0.852
NC_018693_2	2.26\|2821525\|27\|NC_018693\|CRT	2821525-2821551	27	LR798305	uncultured Caudovirales phage genome assembly	33384-33410	4	0.852
NC_018693_2	2.31\|2821750\|27\|NC_018693\|CRT	2821750-2821776	27	KU682439	Stenotrophomonas phage vB_SmaS-DLP_6, complete genome	61554-61580	4	0.852
NC_018693_2	2.32\|2821795\|27\|NC_018693\|CRT	2821795-2821821	27	MN204498	Streptomyces phage Saftant, complete genome	18538-18564	4	0.852
NC_018693_2	2.32\|2821795\|27\|NC_018693\|CRT	2821795-2821821	27	NZ_CP015065	Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence	245-271	4	0.852
NC_018693_2	2.60\|2823064\|27\|NC_018693\|CRT	2823064-2823090	27	AP014498	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C73-MedDCM-OCT-S34-C64, * SEQUENCING IN PROGRESS *, 4 ordered pieces	16648-16674	4	0.852
NC_018693_2	2.60\|2823064\|27\|NC_018693\|CRT	2823064-2823090	27	MH460463	Dickeya phage vB_DsoM_AD1, complete genome	66091-66117	4	0.852
NC_018693_2	2.60\|2823064\|27\|NC_018693\|CRT	2823064-2823090	27	MN693001	Marine virus AFVG_117M47, complete genome	27308-27334	4	0.852
NC_018693_2	2.66\|2823343\|27\|NC_018693\|CRT	2823343-2823369	27	JQ691611	Cronobacter phage CR9, complete genome	9697-9723	4	0.852
NC_018693_2	2.16\|2821057\|27\|NC_018693\|CRT	2821057-2821083	27	NZ_CP020371	Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs417, complete sequence	21522-21548	5	0.815
NC_018693_2	2.16\|2821057\|27\|NC_018693\|CRT	2821057-2821083	27	MH319751	Marine virus AG-345-F15 Ga0172271_13 genomic sequence	4770-4796	5	0.815
NC_018693_2	2.16\|2821057\|27\|NC_018693\|CRT	2821057-2821083	27	MH319751	Marine virus AG-345-F15 Ga0172271_13 genomic sequence	4845-4871	5	0.815
NC_018693_2	2.16\|2821057\|27\|NC_018693\|CRT	2821057-2821083	27	AY576796	Actinoplanes phage phiAsp2, complete genome	7964-7990	5	0.815
NC_018693_2	2.18\|2821147\|27\|NC_018693\|CRT	2821147-2821173	27	NZ_CP052758	Cellulosimicrobium sp. BI34T plasmid pCPRO01, complete sequence	130138-130164	5	0.815
NC_018693_2	2.19\|2821192\|27\|NC_018693\|CRT	2821192-2821218	27	NZ_CP052758	Cellulosimicrobium sp. BI34T plasmid pCPRO01, complete sequence	130138-130164	5	0.815
NC_018693_2	2.20\|2821237\|27\|NC_018693\|CRT	2821237-2821263	27	NZ_CP052758	Cellulosimicrobium sp. BI34T plasmid pCPRO01, complete sequence	130138-130164	5	0.815
NC_018693_2	2.22\|2821345\|27\|NC_018693\|CRT	2821345-2821371	27	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	434198-434224	5	0.815
NC_018693_2	2.24\|2821435\|27\|NC_018693\|CRT	2821435-2821461	27	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	434306-434332	5	0.815
NC_018693_2	2.24\|2821435\|27\|NC_018693\|CRT	2821435-2821461	27	MK279903	Mycobacterium phage Zetzy, complete genome	2505-2531	5	0.815
NC_018693_2	2.24\|2821435\|27\|NC_018693\|CRT	2821435-2821461	27	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	1180231-1180257	5	0.815
NC_018693_2	2.25\|2821480\|27\|NC_018693\|CRT	2821480-2821506	27	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	434198-434224	5	0.815
NC_018693_2	2.25\|2821480\|27\|NC_018693\|CRT	2821480-2821506	27	KU682439	Stenotrophomonas phage vB_SmaS-DLP_6, complete genome	61554-61580	5	0.815
NC_018693_2	2.26\|2821525\|27\|NC_018693\|CRT	2821525-2821551	27	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	2376922-2376948	5	0.815
NC_018693_2	2.26\|2821525\|27\|NC_018693\|CRT	2821525-2821551	27	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	1250387-1250413	5	0.815
NC_018693_2	2.26\|2821525\|27\|NC_018693\|CRT	2821525-2821551	27	KX507344	Streptomyces phage Godpower, complete genome	17467-17493	5	0.815
NC_018693_2	2.26\|2821525\|27\|NC_018693\|CRT	2821525-2821551	27	NC_021298	Streptomyces phage Lika, complete genome	17471-17497	5	0.815
NC_018693_2	2.30\|2821705\|27\|NC_018693\|CRT	2821705-2821731	27	MK279903	Mycobacterium phage Zetzy, complete genome	2505-2531	5	0.815
NC_018693_2	2.31\|2821750\|27\|NC_018693\|CRT	2821750-2821776	27	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	434198-434224	5	0.815
NC_018693_2	2.32\|2821795\|27\|NC_018693\|CRT	2821795-2821821	27	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	434198-434224	5	0.815
NC_018693_2	2.32\|2821795\|27\|NC_018693\|CRT	2821795-2821821	27	KX641263	Mycobacterium phage Kalpine, complete genome	5208-5234	5	0.815
NC_018693_2	2.46\|2822479\|27\|NC_018693\|CRT	2822479-2822505	27	MK450433	Streptomyces phage Sebastisaurus, complete genome	15095-15121	5	0.815
NC_018693_2	2.47\|2822524\|27\|NC_018693\|CRT	2822524-2822550	27	NZ_CP045361	Roseivivax sp. THAF40 plasmid pTHAF40_a, complete sequence	32838-32864	5	0.815
NC_018693_2	2.47\|2822524\|27\|NC_018693\|CRT	2822524-2822550	27	NZ_CP045319	Roseivivax sp. THAF197b plasmid pTHAF197b_a, complete sequence	150938-150964	5	0.815
NC_018693_2	2.72\|2823622\|27\|NC_018693\|CRT	2823622-2823648	27	MN101228	Klebsiella phage KPN4, complete genome	27715-27741	5	0.815
NC_018693_2	2.72\|2823622\|27\|NC_018693\|CRT	2823622-2823648	27	MN434096	Klebsiella phage JIPh_Kp127, complete genome	81960-81986	5	0.815
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	8956-8982	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	9280-9306	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	9433-9459	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	9514-9540	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	9694-9720	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	10072-10098	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	10279-10305	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	10378-10404	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	10468-10494	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	10567-10593	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	21135-21161	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	21459-21485	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	21612-21638	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	21693-21719	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	21873-21899	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	22251-22277	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	22458-22484	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	22557-22583	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	22647-22673	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NZ_CP040338	Bacillus luti strain FJ plasmid unnamed2, complete sequence	22746-22772	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NC_011771	Bacillus cereus AH820 plasmid pAH820_10, complete sequence	10423-10449	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NC_011771	Bacillus cereus AH820 plasmid pAH820_10, complete sequence	10486-10512	6	0.778
NC_018693_2	2.15\|2821012\|27\|NC_018693\|CRT	2821012-2821038	27	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	341551-341577	6	0.778
NC_018693_2	2.15\|2821012\|27\|NC_018693\|CRT	2821012-2821038	27	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2863323-2863349	6	0.778
NC_018693_2	2.19\|2821192\|27\|NC_018693\|CRT	2821192-2821218	27	NZ_CP044073	Pseudomonas oryzihabitans strain FDAARGOS_657 plasmid unnamed2, complete sequence	8742-8768	6	0.778
NC_018693_2	2.22\|2821345\|27\|NC_018693\|CRT	2821345-2821371	27	MK279903	Mycobacterium phage Zetzy, complete genome	2505-2531	6	0.778
NC_018693_2	2.22\|2821345\|27\|NC_018693\|CRT	2821345-2821371	27	MK450433	Streptomyces phage Sebastisaurus, complete genome	15059-15085	6	0.778
NC_018693_2	2.22\|2821345\|27\|NC_018693\|CRT	2821345-2821371	27	MN204498	Streptomyces phage Saftant, complete genome	18538-18564	6	0.778
NC_018693_2	2.24\|2821435\|27\|NC_018693\|CRT	2821435-2821461	27	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	2376922-2376948	6	0.778
NC_018693_2	2.24\|2821435\|27\|NC_018693\|CRT	2821435-2821461	27	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	1250387-1250413	6	0.778
NC_018693_2	2.24\|2821435\|27\|NC_018693\|CRT	2821435-2821461	27	KX507344	Streptomyces phage Godpower, complete genome	17467-17493	6	0.778
NC_018693_2	2.24\|2821435\|27\|NC_018693\|CRT	2821435-2821461	27	NC_021298	Streptomyces phage Lika, complete genome	17471-17497	6	0.778
NC_018693_2	2.24\|2821435\|27\|NC_018693\|CRT	2821435-2821461	27	LR798305	uncultured Caudovirales phage genome assembly	33384-33410	6	0.778
NC_018693_2	2.25\|2821480\|27\|NC_018693\|CRT	2821480-2821506	27	MK279903	Mycobacterium phage Zetzy, complete genome	2505-2531	6	0.778
NC_018693_2	2.25\|2821480\|27\|NC_018693\|CRT	2821480-2821506	27	MK450433	Streptomyces phage Sebastisaurus, complete genome	15059-15085	6	0.778
NC_018693_2	2.25\|2821480\|27\|NC_018693\|CRT	2821480-2821506	27	MN204498	Streptomyces phage Saftant, complete genome	18538-18564	6	0.778
NC_018693_2	2.26\|2821525\|27\|NC_018693\|CRT	2821525-2821551	27	NZ_CP015065	Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence	245-271	6	0.778
NC_018693_2	2.26\|2821525\|27\|NC_018693\|CRT	2821525-2821551	27	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	434306-434332	6	0.778
NC_018693_2	2.26\|2821525\|27\|NC_018693\|CRT	2821525-2821551	27	MK279903	Mycobacterium phage Zetzy, complete genome	2505-2531	6	0.778
NC_018693_2	2.30\|2821705\|27\|NC_018693\|CRT	2821705-2821731	27	KX912252	Pseudoalteromonas phage PHS3, complete genome	7236-7262	6	0.778
NC_018693_2	2.31\|2821750\|27\|NC_018693\|CRT	2821750-2821776	27	MK279903	Mycobacterium phage Zetzy, complete genome	2505-2531	6	0.778
NC_018693_2	2.31\|2821750\|27\|NC_018693\|CRT	2821750-2821776	27	MK450433	Streptomyces phage Sebastisaurus, complete genome	15059-15085	6	0.778
NC_018693_2	2.31\|2821750\|27\|NC_018693\|CRT	2821750-2821776	27	MN204498	Streptomyces phage Saftant, complete genome	18538-18564	6	0.778
NC_018693_2	2.32\|2821795\|27\|NC_018693\|CRT	2821795-2821821	27	NZ_CP021071	Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence	311-337	6	0.778
NC_018693_2	2.32\|2821795\|27\|NC_018693\|CRT	2821795-2821821	27	NZ_CP015063	Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence	1470-1496	6	0.778
NC_018693_2	2.32\|2821795\|27\|NC_018693\|CRT	2821795-2821821	27	MK279903	Mycobacterium phage Zetzy, complete genome	2505-2531	6	0.778
NC_018693_2	2.32\|2821795\|27\|NC_018693\|CRT	2821795-2821821	27	MK450433	Streptomyces phage Sebastisaurus, complete genome	15059-15085	6	0.778
NC_018693_2	2.34\|2821912\|27\|NC_018693\|CRT	2821912-2821938	27	NZ_CP020698	Sulfitobacter sp. D7 plasmid p4SUD7, complete sequence	23625-23651	6	0.778
NC_018693_2	2.38\|2822083\|27\|NC_018693\|CRT	2822083-2822109	27	NZ_CP010859	Marinovum algicola DG 898 plasmid pMaD4, complete sequence	40427-40453	6	0.778
NC_018693_2	2.41\|2822245\|27\|NC_018693\|CRT	2822245-2822271	27	NZ_CP020698	Sulfitobacter sp. D7 plasmid p4SUD7, complete sequence	23625-23651	6	0.778
NC_018693_2	2.44\|2822380\|27\|NC_018693\|CRT	2822380-2822406	27	JQ015307	Pectobacterium phage phiTE, complete genome	118080-118106	6	0.778
NC_018693_2	2.44\|2822380\|27\|NC_018693\|CRT	2822380-2822406	27	KY514263	Pectobacterium phage vB_PatM_CB7, complete genome	9726-9752	6	0.778
NC_018693_2	2.46\|2822479\|27\|NC_018693\|CRT	2822479-2822505	27	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	790196-790222	6	0.778
NC_018693_2	2.55\|2822830\|27\|NC_018693\|CRT	2822830-2822856	27	MN694076	Marine virus AFVG_250M1096, complete genome	34284-34310	6	0.778
NC_018693_2	2.55\|2822830\|27\|NC_018693\|CRT	2822830-2822856	27	MN694359	Marine virus AFVG_250M1098, complete genome	4165-4191	6	0.778
NC_018693_2	2.55\|2822830\|27\|NC_018693\|CRT	2822830-2822856	27	MN694688	Marine virus AFVG_250M1099, complete genome	4186-4212	6	0.778
NC_018693_2	2.55\|2822830\|27\|NC_018693\|CRT	2822830-2822856	27	MN694415	Marine virus AFVG_250M1100, complete genome	4167-4193	6	0.778
NC_018693_2	2.55\|2822830\|27\|NC_018693\|CRT	2822830-2822856	27	MN694502	Marine virus AFVG_250M1097, complete genome	4184-4210	6	0.778
NC_018693_2	2.55\|2822830\|27\|NC_018693\|CRT	2822830-2822856	27	MN062708	Mycobacteriumphage NothingSpecial, complete genome	4830-4856	6	0.778
NC_018693_2	2.56\|2822875\|27\|NC_018693\|CRT	2822875-2822901	27	NZ_CP032531	Bacillus megaterium NCT-2 plasmid pNCT2_3, complete sequence	110573-110599	6	0.778
NC_018693_2	2.56\|2822875\|27\|NC_018693\|CRT	2822875-2822901	27	NZ_CP032531	Bacillus megaterium NCT-2 plasmid pNCT2_3, complete sequence	110609-110635	6	0.778
NC_018693_2	2.56\|2822875\|27\|NC_018693\|CRT	2822875-2822901	27	MT497070	Flavobacterium phage vB_Fsp_elemo2-5C, partial genome	22623-22649	6	0.778
NC_018693_2	2.57\|2822920\|27\|NC_018693\|CRT	2822920-2822946	27	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	813852-813878	6	0.778
NC_018693_2	2.57\|2822920\|27\|NC_018693\|CRT	2822920-2822946	27	NC_019387	Thermus oshimai JL-2 plasmid pTHEOS01, complete sequence	240656-240682	6	0.778
NC_018693_2	2.60\|2823064\|27\|NC_018693\|CRT	2823064-2823090	27	NC_031056	Bacillus phage Deep Blue, complete genome	146725-146751	6	0.778
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	MN693099	Marine virus AFVG_25M184, complete genome	13848-13874	7	0.741
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	MN693189	Marine virus AFVG_25M326, complete genome	18898-18924	7	0.741
NC_018693_2	2.19\|2821192\|27\|NC_018693\|CRT	2821192-2821218	27	NZ_CP012699	Microbacterium sp. No. 7 plasmid B, complete sequence	89553-89579	7	0.741
NC_018693_2	2.19\|2821192\|27\|NC_018693\|CRT	2821192-2821218	27	NZ_CP044072	Pseudomonas oryzihabitans strain FDAARGOS_657 plasmid unnamed1, complete sequence	88967-88993	7	0.741
NC_018693_2	2.46\|2822479\|27\|NC_018693\|CRT	2822479-2822505	27	NZ_CP013069	Pannonibacter phragmitetus strain 31801 plasmid p.p-1, complete sequence	316501-316527	7	0.741
NC_018693_2	2.46\|2822479\|27\|NC_018693\|CRT	2822479-2822505	27	NZ_CP032313	Pannonibacter phragmitetus BB plasmid p.BB_1, complete sequence	186437-186463	7	0.741
NC_018693_2	2.55\|2822830\|27\|NC_018693\|CRT	2822830-2822856	27	MN908690	Microbacterium phage Hubbs, complete genome	25999-26025	7	0.741
NC_018693_2	2.55\|2822830\|27\|NC_018693\|CRT	2822830-2822856	27	MN096374	Microbacterium phage Roman, complete genome	25847-25873	7	0.741
NC_018693_2	2.55\|2822830\|27\|NC_018693\|CRT	2822830-2822856	27	MK937596	Microbacterium phage PhillyPhilly, complete genome	25380-25406	7	0.741
NC_018693_2	2.55\|2822830\|27\|NC_018693\|CRT	2822830-2822856	27	MK919474	Microbacterium phage Lupine, complete genome	25201-25227	7	0.741
NC_018693_2	2.60\|2823064\|27\|NC_018693\|CRT	2823064-2823090	27	MK613348	Roseobacter phage CRP-6, complete genome	35766-35792	7	0.741
NC_018693_2	2.9\|2820760\|27\|NC_018693\|CRT	2820760-2820786	27	NC_015059	Granulicella tundricola MP5ACTX9 plasmid pACIX904, complete sequence	19531-19557	8	0.704

1. spacer 2.60|2823064|27|NC_018693|CRT matches to MN101228 (Klebsiella phage KPN4, complete genome) position: , mismatch: 2, identity: 0.926

caaggtgctcaaggtaacactggtgct	CRISPR spacer
caaggtcctcagggtaacactggtgct	Protospacer
****** ****.***************

2. spacer 2.12|2820895|27|NC_018693|CRT matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.889

acggggcctcggggtaacacgggcgct	CRISPR spacer
gcgggggctcgggggaacacgggcgct	Protospacer
.***** ******* ************

3. spacer 2.37|2822038|27|NC_018693|CRT matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 3, identity: 0.889

acggggcctcggggtaacacgggcgct	CRISPR spacer
gcgggggctcgggggaacacgggcgct	Protospacer
.***** ******* ************

4. spacer 2.66|2823343|27|NC_018693|CRT matches to MT380195 (Klebsiella phage KP_LZD_B01, complete genome) position: , mismatch: 3, identity: 0.889

actggacctcaaggtaacacgggggct	CRISPR spacer
actggtcctcaaggtaacaagggggat	Protospacer
***** ************* ***** *

5. spacer 2.66|2823343|27|NC_018693|CRT matches to KX845404 (Klebsiella phage vB_Kpn_IME260, complete genome) position: , mismatch: 3, identity: 0.889

actggacctcaaggtaacacgggggct	CRISPR spacer
actggtcctcaaggtaacaagggggat	Protospacer
***** ************* ***** *

6. spacer 2.9|2820760|27|NC_018693|CRT matches to AP013411 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C108A-MedDCM-OCT-S29-C43) position: , mismatch: 4, identity: 0.852

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggaccacaaggtaca	Protospacer
***************** *.*****

7. spacer 2.9|2820760|27|NC_018693|CRT matches to AP013669 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C108A-MedDCM-OCT-S25-C43, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 4, identity: 0.852

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggaccacaaggtaca	Protospacer
***************** *.*****

8. spacer 2.9|2820760|27|NC_018693|CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 4, identity: 0.852

actggacctactggacctcgaggtaac	CRISPR spacer
atcggacctactggtcctcaaggtaac	Protospacer
*..*********** ****.*******

9. spacer 2.16|2821057|27|NC_018693|CRT matches to HQ632825 (Prochlorococcus phage P-SSM5 genomic sequence) position: , mismatch: 4, identity: 0.852

actggacctcctggacctggaggtgca	CRISPR spacer
cctggaccacctggacctggaggacca	Protospacer
 ******* **************  **

10. spacer 2.16|2821057|27|NC_018693|CRT matches to AY939844 (Prochlorococcus phage P-SSM2, complete genome) position: , mismatch: 4, identity: 0.852

actggacctcctggacctggaggtgca	CRISPR spacer
cctggaccacctggacctggaggacca	Protospacer
 ******* **************  **

11. spacer 2.22|2821345|27|NC_018693|CRT matches to KU682439 (Stenotrophomonas phage vB_SmaS-DLP_6, complete genome) position: , mismatch: 4, identity: 0.852

cgaggtaacacgggcgctaccggtgct	CRISPR spacer
cgcggtaacacgggcgcgaccggttcg	Protospacer
** ************** ****** *

12. spacer 2.23|2821390|27|NC_018693|CRT matches to NZ_CP018048 (Pseudomonas aeruginosa strain DN1 plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.852

cgaggtaactcgggcgctaccggcgct	CRISPR spacer
cagggcaactcgggcgctacaggcgct	Protospacer
*..**.************** ******

13. spacer 2.24|2821435|27|NC_018693|CRT matches to MN204498 (Streptomyces phage Saftant, complete genome) position: , mismatch: 4, identity: 0.852

cgaggtgccacgggcgctaccggcgcc	CRISPR spacer
actggtgccacgggcgctaccggtgcc	Protospacer
   ********************.***

14. spacer 2.24|2821435|27|NC_018693|CRT matches to NZ_CP015065 (Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence) position: , mismatch: 4, identity: 0.852

cgaggtgccacgggcgctaccggcgcc	CRISPR spacer
acaggtgccacgggcgcgaccggtgcc	Protospacer
  *************** *****.***

15. spacer 2.26|2821525|27|NC_018693|CRT matches to MN204498 (Streptomyces phage Saftant, complete genome) position: , mismatch: 4, identity: 0.852

cgtggtgccacgggcgctaccggcgct	CRISPR spacer
actggtgccacgggcgctaccggtgcc	Protospacer
  *********************.**.

16. spacer 2.26|2821525|27|NC_018693|CRT matches to LR798305 (uncultured Caudovirales phage genome assembly) position: , mismatch: 4, identity: 0.852

cgtggtgccacgggcgctaccggcgct	CRISPR spacer
actggtgctacaggcgctaccggcgct	Protospacer
  ******.**.***************

17. spacer 2.31|2821750|27|NC_018693|CRT matches to KU682439 (Stenotrophomonas phage vB_SmaS-DLP_6, complete genome) position: , mismatch: 4, identity: 0.852

cgaggtaacacgggcgctaccggtgct	CRISPR spacer
cgcggtaacacgggcgcgaccggttcg	Protospacer
** ************** ****** *

18. spacer 2.32|2821795|27|NC_018693|CRT matches to MN204498 (Streptomyces phage Saftant, complete genome) position: , mismatch: 4, identity: 0.852

cgaggtgccacgggcgctaccggtgct	CRISPR spacer
actggtgccacgggcgctaccggtgcc	Protospacer
   ***********************.

19. spacer 2.32|2821795|27|NC_018693|CRT matches to NZ_CP015065 (Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence) position: , mismatch: 4, identity: 0.852

cgaggtgccacgggcgctaccggtgct	CRISPR spacer
acaggtgccacgggcgcgaccggtgcc	Protospacer
  *************** ********.

20. spacer 2.60|2823064|27|NC_018693|CRT matches to AP014498 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C73-MedDCM-OCT-S34-C64, *** SEQUENCING IN PROGRESS ***, 4 ordered pieces) position: , mismatch: 4, identity: 0.852

caaggtgctcaaggtaacactggtgct	CRISPR spacer
caaggtgctcaaggtacaactggtagt	Protospacer
****************  ******. *

21. spacer 2.60|2823064|27|NC_018693|CRT matches to MH460463 (Dickeya phage vB_DsoM_AD1, complete genome) position: , mismatch: 4, identity: 0.852

caaggtgctcaaggtaacactggtgct	CRISPR spacer
gtaggtgctacaggtaacactggtgct	Protospacer
  *******  ****************

22. spacer 2.60|2823064|27|NC_018693|CRT matches to MN693001 (Marine virus AFVG_117M47, complete genome) position: , mismatch: 4, identity: 0.852

caaggtgctcaaggtaacactggtgct	CRISPR spacer
ccagctgctccaggtaacactggtgat	Protospacer
* ** ***** ************** *

23. spacer 2.66|2823343|27|NC_018693|CRT matches to JQ691611 (Cronobacter phage CR9, complete genome) position: , mismatch: 4, identity: 0.852

actggacctcaaggtaacacgggggct	CRISPR spacer
actggtcctcaaggtaacacaggtcct	Protospacer
***** **************.**  **

24. spacer 2.16|2821057|27|NC_018693|CRT matches to NZ_CP020371 (Candidatus Thiodictyon syntrophicum strain Cad16T plasmid pTs417, complete sequence) position: , mismatch: 5, identity: 0.815

actggacctcctggacctggaggtgca	CRISPR spacer
cctggccctcctggacatggaggtcga	Protospacer
 **** ********** *******  *

25. spacer 2.16|2821057|27|NC_018693|CRT matches to MH319751 (Marine virus AG-345-F15 Ga0172271_13 genomic sequence) position: , mismatch: 5, identity: 0.815

actggacctcctggacctggaggtgca	CRISPR spacer
cctggacctcctggtcctgaaggtcct	Protospacer
 ************* ****.**** *

26. spacer 2.16|2821057|27|NC_018693|CRT matches to MH319751 (Marine virus AG-345-F15 Ga0172271_13 genomic sequence) position: , mismatch: 5, identity: 0.815

actggacctcctggacctggaggtgca	CRISPR spacer
cctggtcctcctggacctgaaggtcct	Protospacer
 **** *************.**** *

27. spacer 2.16|2821057|27|NC_018693|CRT matches to AY576796 (Actinoplanes phage phiAsp2, complete genome) position: , mismatch: 5, identity: 0.815

actggacctcctggacctggaggtgca	CRISPR spacer
cgtggacctcctggacctggtggagga	Protospacer
  ****************** ** * *

28. spacer 2.18|2821147|27|NC_018693|CRT matches to NZ_CP052758 (Cellulosimicrobium sp. BI34T plasmid pCPRO01, complete sequence) position: , mismatch: 5, identity: 0.815

actgggcctactggacctcgaggtaac	CRISPR spacer
cctgggcctcctcgacctcgaggtact	Protospacer
 ******** ** ************ .

29. spacer 2.19|2821192|27|NC_018693|CRT matches to NZ_CP052758 (Cellulosimicrobium sp. BI34T plasmid pCPRO01, complete sequence) position: , mismatch: 5, identity: 0.815

actggacctcctggacctcgaggtaac	CRISPR spacer
cctgggcctcctcgacctcgaggtact	Protospacer
 ****.****** ************ .

30. spacer 2.20|2821237|27|NC_018693|CRT matches to NZ_CP052758 (Cellulosimicrobium sp. BI34T plasmid pCPRO01, complete sequence) position: , mismatch: 5, identity: 0.815

actgggcctactggacctcgaggtaac	CRISPR spacer
cctgggcctcctcgacctcgaggtact	Protospacer
 ******** ** ************ .

31. spacer 2.22|2821345|27|NC_018693|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

cgaggtaacacgggcgctaccggtgct	CRISPR spacer
acgggtacgacgggcgctaccggtgct	Protospacer
  .****  ******************

32. spacer 2.24|2821435|27|NC_018693|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

cgaggtgccacgggcgctaccggcgcc	CRISPR spacer
acgggtgccacaggcgcgaccggcgcc	Protospacer
  .********.***** *********

33. spacer 2.24|2821435|27|NC_018693|CRT matches to MK279903 (Mycobacterium phage Zetzy, complete genome) position: , mismatch: 5, identity: 0.815

cgaggtgccacgggcgctaccggcgcc	CRISPR spacer
aaaggtgacacgggcgctaccggcccg	Protospacer
 .***** **************** *

34. spacer 2.24|2821435|27|NC_018693|CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 5, identity: 0.815

cgaggtgccacgggcgctaccggcgcc	CRISPR spacer
caccgtgccgcgggcgcgaccggcgcc	Protospacer
*.  *****.******* *********

35. spacer 2.25|2821480|27|NC_018693|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

ggaggtaacacgggcgctaccggtgct	CRISPR spacer
acgggtacgacgggcgctaccggtgct	Protospacer
. .****  ******************

36. spacer 2.25|2821480|27|NC_018693|CRT matches to KU682439 (Stenotrophomonas phage vB_SmaS-DLP_6, complete genome) position: , mismatch: 5, identity: 0.815

ggaggtaacacgggcgctaccggtgct	CRISPR spacer
cgcggtaacacgggcgcgaccggttcg	Protospacer
 * ************** ****** *

37. spacer 2.26|2821525|27|NC_018693|CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.815

cgtggtgccacgggcgctaccggcgct	CRISPR spacer
accggcgccacgggcgcaaccggcgct	Protospacer
  .**.*********** *********

38. spacer 2.26|2821525|27|NC_018693|CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 5, identity: 0.815

cgtggtgccacgggcgctaccggcgct	CRISPR spacer
accggcgccacgggcgcaaccggcgct	Protospacer
  .**.*********** *********

39. spacer 2.26|2821525|27|NC_018693|CRT matches to KX507344 (Streptomyces phage Godpower, complete genome) position: , mismatch: 5, identity: 0.815

cgtggtgccacgggcgctaccggcgct	CRISPR spacer
actggagccaccggcgctaccggcgcg	Protospacer
  *** ***** **************

40. spacer 2.26|2821525|27|NC_018693|CRT matches to NC_021298 (Streptomyces phage Lika, complete genome) position: , mismatch: 5, identity: 0.815

cgtggtgccacgggcgctaccggcgct	CRISPR spacer
actggagccaccggcgctaccggcgcg	Protospacer
  *** ***** **************

41. spacer 2.30|2821705|27|NC_018693|CRT matches to MK279903 (Mycobacterium phage Zetzy, complete genome) position: , mismatch: 5, identity: 0.815

cgaggtgactcgggcgctaccggcgct	CRISPR spacer
aaaggtgacacgggcgctaccggcccg	Protospacer
 .******* ************** *

42. spacer 2.31|2821750|27|NC_018693|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

cgaggtaacacgggcgctaccggtgct	CRISPR spacer
acgggtacgacgggcgctaccggtgct	Protospacer
  .****  ******************

43. spacer 2.32|2821795|27|NC_018693|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

cgaggtgccacgggcgctaccggtgct	CRISPR spacer
acgggtacgacgggcgctaccggtgct	Protospacer
  .***.* ******************

44. spacer 2.32|2821795|27|NC_018693|CRT matches to KX641263 (Mycobacterium phage Kalpine, complete genome) position: , mismatch: 5, identity: 0.815

cgaggtgccacgggcgctaccggtgct	CRISPR spacer
aagggtgccaagggcgataccggtgct	Protospacer
 ..******* ***** **********

45. spacer 2.46|2822479|27|NC_018693|CRT matches to MK450433 (Streptomyces phage Sebastisaurus, complete genome) position: , mismatch: 5, identity: 0.815

ggaggtaacacgggcgctgccggtgct	CRISPR spacer
aagggtgacacgggcgctgcgggtgct	Protospacer
...***.************* ******

46. spacer 2.47|2822524|27|NC_018693|CRT matches to NZ_CP045361 (Roseivivax sp. THAF40 plasmid pTHAF40_a, complete sequence) position: , mismatch: 5, identity: 0.815

cggggaaccaggggcgctaccggcgct	CRISPR spacer
cggggaaccaggtgcgctaccgcctgg	Protospacer
************ ********* *

47. spacer 2.47|2822524|27|NC_018693|CRT matches to NZ_CP045319 (Roseivivax sp. THAF197b plasmid pTHAF197b_a, complete sequence) position: , mismatch: 5, identity: 0.815

cggggaaccaggggcgctaccggcgct	CRISPR spacer
cggggaaccaggtgcgctaccgcctgg	Protospacer
************ ********* *

48. spacer 2.72|2823622|27|NC_018693|CRT matches to MN101228 (Klebsiella phage KPN4, complete genome) position: , mismatch: 5, identity: 0.815

gctggacctcggggtaacactggtgct	CRISPR spacer
caaggtcctcagggtaacactggtgct	Protospacer
   ** ****.****************

49. spacer 2.72|2823622|27|NC_018693|CRT matches to MN434096 (Klebsiella phage JIPh_Kp127, complete genome) position: , mismatch: 5, identity: 0.815

gctggacctcggggtaacactggtgct	CRISPR spacer
cagggccctcagggtaacactggtgct	Protospacer
   ** ****.****************

50. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

51. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

52. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

53. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

54. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

55. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

56. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

57. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

58. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

59. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

60. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

61. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

62. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

63. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

64. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

65. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

66. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

67. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

68. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

69. spacer 2.9|2820760|27|NC_018693|CRT matches to NZ_CP040338 (Bacillus luti strain FJ plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

70. spacer 2.9|2820760|27|NC_018693|CRT matches to NC_011771 (Bacillus cereus AH820 plasmid pAH820_10, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

71. spacer 2.9|2820760|27|NC_018693|CRT matches to NC_011771 (Bacillus cereus AH820 plasmid pAH820_10, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctactggacctcgaggtaac	CRISPR spacer
actggacctactggacctacaggagct	Protospacer
******************  *** . .

72. spacer 2.15|2821012|27|NC_018693|CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 6, identity: 0.778

actgggcctactggatctcgaggtaac	CRISPR spacer
cctgggcctactggatctcgatctggg	Protospacer
 ********************  *..

73. spacer 2.15|2821012|27|NC_018693|CRT matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 6, identity: 0.778

actgggcctactggatctcgaggtaac	CRISPR spacer
cctgggcccactggatcttgaggtgct	Protospacer
 *******.*********.*****. .

74. spacer 2.19|2821192|27|NC_018693|CRT matches to NZ_CP044073 (Pseudomonas oryzihabitans strain FDAARGOS_657 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctcctggacctcgaggtaac	CRISPR spacer
cgtcgacctcctggacctcgaggacat	Protospacer
  * *******************  *.

75. spacer 2.22|2821345|27|NC_018693|CRT matches to MK279903 (Mycobacterium phage Zetzy, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtaacacgggcgctaccggtgct	CRISPR spacer
aaaggtgacacgggcgctaccggcccg	Protospacer
 .****.****************. *

76. spacer 2.22|2821345|27|NC_018693|CRT matches to MK450433 (Streptomyces phage Sebastisaurus, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtaacacgggcgctaccggtgct	CRISPR spacer
aagggtgacacgggcgctaccggttcc	Protospacer
 ..***.***************** *.

77. spacer 2.22|2821345|27|NC_018693|CRT matches to MN204498 (Streptomyces phage Saftant, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtaacacgggcgctaccggtgct	CRISPR spacer
actggtgccacgggcgctaccggtgcc	Protospacer
   ***. ******************.

78. spacer 2.24|2821435|27|NC_018693|CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.778

cgaggtgccacgggcgctaccggcgcc	CRISPR spacer
accggcgccacgggcgcaaccggcgct	Protospacer
   **.*********** ********.

79. spacer 2.24|2821435|27|NC_018693|CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 6, identity: 0.778

cgaggtgccacgggcgctaccggcgcc	CRISPR spacer
accggcgccacgggcgcaaccggcgct	Protospacer
   **.*********** ********.

80. spacer 2.24|2821435|27|NC_018693|CRT matches to KX507344 (Streptomyces phage Godpower, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtgccacgggcgctaccggcgcc	CRISPR spacer
actggagccaccggcgctaccggcgcg	Protospacer
   ** ***** **************

81. spacer 2.24|2821435|27|NC_018693|CRT matches to NC_021298 (Streptomyces phage Lika, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtgccacgggcgctaccggcgcc	CRISPR spacer
actggagccaccggcgctaccggcgcg	Protospacer
   ** ***** **************

82. spacer 2.24|2821435|27|NC_018693|CRT matches to LR798305 (uncultured Caudovirales phage genome assembly) position: , mismatch: 6, identity: 0.778

cgaggtgccacgggcgctaccggcgcc	CRISPR spacer
actggtgctacaggcgctaccggcgct	Protospacer
   *****.**.**************.

83. spacer 2.25|2821480|27|NC_018693|CRT matches to MK279903 (Mycobacterium phage Zetzy, complete genome) position: , mismatch: 6, identity: 0.778

ggaggtaacacgggcgctaccggtgct	CRISPR spacer
aaaggtgacacgggcgctaccggcccg	Protospacer
..****.****************. *

84. spacer 2.25|2821480|27|NC_018693|CRT matches to MK450433 (Streptomyces phage Sebastisaurus, complete genome) position: , mismatch: 6, identity: 0.778

ggaggtaacacgggcgctaccggtgct	CRISPR spacer
aagggtgacacgggcgctaccggttcc	Protospacer
...***.***************** *.

85. spacer 2.25|2821480|27|NC_018693|CRT matches to MN204498 (Streptomyces phage Saftant, complete genome) position: , mismatch: 6, identity: 0.778

ggaggtaacacgggcgctaccggtgct	CRISPR spacer
actggtgccacgggcgctaccggtgcc	Protospacer
.  ***. ******************.

86. spacer 2.26|2821525|27|NC_018693|CRT matches to NZ_CP015065 (Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence) position: , mismatch: 6, identity: 0.778

cgtggtgccacgggcgctaccggcgct	CRISPR spacer
acaggtgccacgggcgcgaccggtgcc	Protospacer
   ************** *****.**.

87. spacer 2.26|2821525|27|NC_018693|CRT matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

cgtggtgccacgggcgctaccggcgct	CRISPR spacer
acgggtgccacaggcgcgaccggcgcc	Protospacer
   ********.***** ********.

88. spacer 2.26|2821525|27|NC_018693|CRT matches to MK279903 (Mycobacterium phage Zetzy, complete genome) position: , mismatch: 6, identity: 0.778

cgtggtgccacgggcgctaccggcgct	CRISPR spacer
aaaggtgacacgggcgctaccggcccg	Protospacer
 . **** **************** *

89. spacer 2.30|2821705|27|NC_018693|CRT matches to KX912252 (Pseudoalteromonas phage PHS3, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtgactcgggcgctaccggcgct	CRISPR spacer
gtaggtgactttggcgctaccggcggc	Protospacer
  ********. ************* .

90. spacer 2.31|2821750|27|NC_018693|CRT matches to MK279903 (Mycobacterium phage Zetzy, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtaacacgggcgctaccggtgct	CRISPR spacer
aaaggtgacacgggcgctaccggcccg	Protospacer
 .****.****************. *

91. spacer 2.31|2821750|27|NC_018693|CRT matches to MK450433 (Streptomyces phage Sebastisaurus, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtaacacgggcgctaccggtgct	CRISPR spacer
aagggtgacacgggcgctaccggttcc	Protospacer
 ..***.***************** *.

92. spacer 2.31|2821750|27|NC_018693|CRT matches to MN204498 (Streptomyces phage Saftant, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtaacacgggcgctaccggtgct	CRISPR spacer
actggtgccacgggcgctaccggtgcc	Protospacer
   ***. ******************.

93. spacer 2.32|2821795|27|NC_018693|CRT matches to NZ_CP021071 (Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence) position: , mismatch: 6, identity: 0.778

cgaggtgccacgggcgctaccggtgct	CRISPR spacer
acgggtgctacgggcgataccggtgcc	Protospacer
  .*****.******* *********.

94. spacer 2.32|2821795|27|NC_018693|CRT matches to NZ_CP015063 (Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence) position: , mismatch: 6, identity: 0.778

cgaggtgccacgggcgctaccggtgct	CRISPR spacer
acgggtgctacgggcgataccggtgcc	Protospacer
  .*****.******* *********.

95. spacer 2.32|2821795|27|NC_018693|CRT matches to MK279903 (Mycobacterium phage Zetzy, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtgccacgggcgctaccggtgct	CRISPR spacer
aaaggtgacacgggcgctaccggcccg	Protospacer
 .***** ***************. *

96. spacer 2.32|2821795|27|NC_018693|CRT matches to MK450433 (Streptomyces phage Sebastisaurus, complete genome) position: , mismatch: 6, identity: 0.778

cgaggtgccacgggcgctaccggtgct	CRISPR spacer
aagggtgacacgggcgctaccggttcc	Protospacer
 ..**** **************** *.

97. spacer 2.34|2821912|27|NC_018693|CRT matches to NZ_CP020698 (Sulfitobacter sp. D7 plasmid p4SUD7, complete sequence) position: , mismatch: 6, identity: 0.778

cctggccctcggggtaacccgggcgca	CRISPR spacer
ggaggcgctcggggtgacccgggcgct	Protospacer
   *** ********.**********

98. spacer 2.38|2822083|27|NC_018693|CRT matches to NZ_CP010859 (Marinovum algicola DG 898 plasmid pMaD4, complete sequence) position: , mismatch: 6, identity: 0.778

actggatctcgaggtgccacgggcgct	CRISPR spacer
cgccgatctcgaggtgctgcgggcgct	Protospacer
  . *************..********

99. spacer 2.41|2822245|27|NC_018693|CRT matches to NZ_CP020698 (Sulfitobacter sp. D7 plasmid p4SUD7, complete sequence) position: , mismatch: 6, identity: 0.778

cctggccctcggggtaacccgggcgca	CRISPR spacer
ggaggcgctcggggtgacccgggcgct	Protospacer
   *** ********.**********

100. spacer 2.44|2822380|27|NC_018693|CRT matches to JQ015307 (Pectobacterium phage phiTE, complete genome) position: , mismatch: 6, identity: 0.778

actgggcctcgtggtaacacgggcgct	CRISPR spacer
actggtcctcgtggtaacacaggtctg	Protospacer
***** **************.**. .

101. spacer 2.44|2822380|27|NC_018693|CRT matches to KY514263 (Pectobacterium phage vB_PatM_CB7, complete genome) position: , mismatch: 6, identity: 0.778

actgggcctcgtggtaacacgggcgct	CRISPR spacer
actggtcctcgtggtaacacaggtctg	Protospacer
***** **************.**. .

102. spacer 2.46|2822479|27|NC_018693|CRT matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

ggaggtaacacgggcgctgccggtgct	CRISPR spacer
tatcgcaacacgggcgctgcccgtgct	Protospacer
 .  *.*************** *****

103. spacer 2.55|2822830|27|NC_018693|CRT matches to MN694076 (Marine virus AFVG_250M1096, complete genome) position: , mismatch: 6, identity: 0.778

actgggccttctggacctcggggtaac	CRISPR spacer
attgggccttctggacctgggggaggg	Protospacer
*.**************** **** ..

104. spacer 2.55|2822830|27|NC_018693|CRT matches to MN694359 (Marine virus AFVG_250M1098, complete genome) position: , mismatch: 6, identity: 0.778

actgggccttctggacctcggggtaac	CRISPR spacer
attgggccttctggacctgggggaggg	Protospacer
*.**************** **** ..

105. spacer 2.55|2822830|27|NC_018693|CRT matches to MN694688 (Marine virus AFVG_250M1099, complete genome) position: , mismatch: 6, identity: 0.778

actgggccttctggacctcggggtaac	CRISPR spacer
attgggccttctggacctgggggaggg	Protospacer
*.**************** **** ..

106. spacer 2.55|2822830|27|NC_018693|CRT matches to MN694415 (Marine virus AFVG_250M1100, complete genome) position: , mismatch: 6, identity: 0.778

actgggccttctggacctcggggtaac	CRISPR spacer
attgggccttctggacctgggggaggg	Protospacer
*.**************** **** ..

107. spacer 2.55|2822830|27|NC_018693|CRT matches to MN694502 (Marine virus AFVG_250M1097, complete genome) position: , mismatch: 6, identity: 0.778

actgggccttctggacctcggggtaac	CRISPR spacer
attgggccttctggacctgggggaggg	Protospacer
*.**************** **** ..

108. spacer 2.55|2822830|27|NC_018693|CRT matches to MN062708 (Mycobacteriumphage NothingSpecial, complete genome) position: , mismatch: 6, identity: 0.778

actgggccttctggacctcggggtaac	CRISPR spacer
gctgggccttctggaccttgcggtcct	Protospacer
.*****************.* ***  .

109. spacer 2.56|2822875|27|NC_018693|CRT matches to NZ_CP032531 (Bacillus megaterium NCT-2 plasmid pNCT2_3, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctacaggacctcgaggaacc	CRISPR spacer
caaggagctacaggacctcgaggagtc	Protospacer
   *** *****************..*

110. spacer 2.56|2822875|27|NC_018693|CRT matches to NZ_CP032531 (Bacillus megaterium NCT-2 plasmid pNCT2_3, complete sequence) position: , mismatch: 6, identity: 0.778

actggacctacaggacctcgaggaacc	CRISPR spacer
cgaggagctacaggacctcgaggagct	Protospacer
   *** *****************.*.

111. spacer 2.56|2822875|27|NC_018693|CRT matches to MT497070 (Flavobacterium phage vB_Fsp_elemo2-5C, partial genome) position: , mismatch: 6, identity: 0.778

actggacctacaggacctcgaggaacc	CRISPR spacer
caaggacctacaggacctcaaggacct	Protospacer
   ****************.**** *.

112. spacer 2.57|2822920|27|NC_018693|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 6, identity: 0.778

actggccctcctggccctcggggaaac	CRISPR spacer
gctggccctcctggccctccgggtcgg	Protospacer
.****************** ***  .

113. spacer 2.57|2822920|27|NC_018693|CRT matches to NC_019387 (Thermus oshimai JL-2 plasmid pTHEOS01, complete sequence) position: , mismatch: 6, identity: 0.778

actggccctcctggccctcggggaaac	CRISPR spacer
cctggccctcctcgccctctgggagtg	Protospacer
 *********** ****** ****.

114. spacer 2.60|2823064|27|NC_018693|CRT matches to NC_031056 (Bacillus phage Deep Blue, complete genome) position: , mismatch: 6, identity: 0.778

caaggtgctcaaggtaacactggtgct	CRISPR spacer
atggatggtcaaggtaacactggtgca	Protospacer
  .*.** ******************

115. spacer 2.9|2820760|27|NC_018693|CRT matches to MN693099 (Marine virus AFVG_25M184, complete genome) position: , mismatch: 7, identity: 0.741

actggacctactggacctcgaggtaac	CRISPR spacer
caaggacctactggacctcaaggtcct	Protospacer
   ****************.****  .

116. spacer 2.9|2820760|27|NC_018693|CRT matches to MN693189 (Marine virus AFVG_25M326, complete genome) position: , mismatch: 7, identity: 0.741

actggacctactggacctcgaggtaac	CRISPR spacer
caaggacctactggacctcaaggtgct	Protospacer
   ****************.****. .

117. spacer 2.19|2821192|27|NC_018693|CRT matches to NZ_CP012699 (Microbacterium sp. No. 7 plasmid B, complete sequence) position: , mismatch: 7, identity: 0.741

actggacctcctggacctcgaggtaac	CRISPR spacer
caaggaccacctggacctcgaggtgtt	Protospacer
   ***** ***************. .

118. spacer 2.19|2821192|27|NC_018693|CRT matches to NZ_CP044072 (Pseudomonas oryzihabitans strain FDAARGOS_657 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.741

actggacctcctggacctcgaggtaac	CRISPR spacer
cgtcgacctcctggacctcgaggacgt	Protospacer
  * *******************  ..

119. spacer 2.46|2822479|27|NC_018693|CRT matches to NZ_CP013069 (Pannonibacter phragmitetus strain 31801 plasmid p.p-1, complete sequence) position: , mismatch: 7, identity: 0.741

ggaggtaacacgggcgctgccggtgct	CRISPR spacer
gagtacgacacgggcgctgccggtgcc	Protospacer
*.. ...*******************.

120. spacer 2.46|2822479|27|NC_018693|CRT matches to NZ_CP032313 (Pannonibacter phragmitetus BB plasmid p.BB_1, complete sequence) position: , mismatch: 7, identity: 0.741

ggaggtaacacgggcgctgccggtgct	CRISPR spacer
gagcacgacacgggcgctgccggtgcc	Protospacer
*.. ...*******************.

121. spacer 2.55|2822830|27|NC_018693|CRT matches to MN908690 (Microbacterium phage Hubbs, complete genome) position: , mismatch: 7, identity: 0.741

actgggccttctggacctcggggtaac	CRISPR spacer
ctaggaccttctggacctcggggtcct	Protospacer
 . **.******************  .

122. spacer 2.55|2822830|27|NC_018693|CRT matches to MN096374 (Microbacterium phage Roman, complete genome) position: , mismatch: 7, identity: 0.741

actgggccttctggacctcggggtaac	CRISPR spacer
ctaggaccttctggacctcggggtcct	Protospacer
 . **.******************  .

123. spacer 2.55|2822830|27|NC_018693|CRT matches to MK937596 (Microbacterium phage PhillyPhilly, complete genome) position: , mismatch: 7, identity: 0.741

actgggccttctggacctcggggtaac	CRISPR spacer
ctaggaccttctggacctcggggtcct	Protospacer
 . **.******************  .

124. spacer 2.55|2822830|27|NC_018693|CRT matches to MK919474 (Microbacterium phage Lupine, complete genome) position: , mismatch: 7, identity: 0.741

actgggccttctggacctcggggtaac	CRISPR spacer
ctaggaccttctggacctcggggtcct	Protospacer
 . **.******************  .

125. spacer 2.60|2823064|27|NC_018693|CRT matches to MK613348 (Roseobacter phage CRP-6, complete genome) position: , mismatch: 7, identity: 0.741

caaggtgctcaaggtaacactggtgct	CRISPR spacer
gttggcgctcaaggtaacactggtaac	Protospacer
   **.******************. .

126. spacer 2.9|2820760|27|NC_018693|CRT matches to NC_015059 (Granulicella tundricola MP5ACTX9 plasmid pACIX904, complete sequence) position: , mismatch: 8, identity: 0.704

actggacctactggacctcgaggtaac	CRISPR spacer
caatgacctactggacctcgaggccga	Protospacer
    *******************. .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1176635 : 1224796

Clostridium_phage(18.18%)

portal,protease,terminase,coat,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000998630.1\|1176635_1176917_+\|terminase	P27 family phage terminase small subunit	NA	NA	NA	NA
WP_087991529.1\|1176971_1177241_+	hypothetical protein	NA	NA	NA	NA
WP_000522672.1\|1177256_1178558_+\|portal	phage portal protein	A0A060AFC9	Staphylococcus_phage	9.9e-83	40.4
WP_000781512.1\|1178535_1180227_+\|capsid	phage major capsid protein	A0A1I9KK60	Lactobacillus_phage	1.6e-53	27.3
WP_001194094.1\|1180327_1180957_-	hypothetical protein	NA	NA	NA	NA
WP_000443339.1\|1181017_1181320_-	hypothetical protein	NA	NA	NA	NA
WP_000799107.1\|1181549_1181771_+	hypothetical protein	NA	NA	NA	NA
WP_000804005.1\|1181863_1183369_+	recombinase family protein	I2E8X2	Clostridium_phage	3.3e-45	29.2
WP_000701123.1\|1183383_1184670_-	hypothetical protein	NA	NA	NA	NA
WP_001026008.1\|1184887_1186768_+	ABC transporter permease	NA	NA	NA	NA
WP_000648323.1\|1186882_1187170_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	2.6e-12	57.4
WP_001089055.1\|1187430_1188381_+\|protease	serine protease	A0A127AWU5	Bacillus_phage	2.0e-96	58.1
WP_001259904.1\|1188421_1188730_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000877946.1\|1188836_1189772_+	aldo/keto reductase	NA	NA	NA	NA
WP_000162608.1\|1190018_1190243_-	hypothetical protein	NA	NA	NA	NA
WP_000426310.1\|1190327_1190675_-	DUF4257 domain-containing protein	NA	NA	NA	NA
WP_001019817.1\|1190869_1191397_+	DUF664 domain-containing protein	NA	NA	NA	NA
WP_001073069.1\|1191579_1192632_+	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_000040622.1\|1192840_1194823_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.1e-23	38.8
WP_000539579.1\|1195036_1195342_+	hypothetical protein	NA	NA	NA	NA
WP_000965088.1\|1195596_1195962_+	DUF3979 family protein	NA	NA	NA	NA
WP_000370197.1\|1195998_1197039_-	hypothetical protein	NA	NA	NA	NA
WP_000106367.1\|1197280_1197724_+	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	4.8e-45	62.1
WP_000488204.1\|1197825_1198281_+	DUF3939 domain-containing protein	NA	NA	NA	NA
WP_000798331.1\|1198545_1199490_+	hypothetical protein	NA	NA	NA	NA
WP_000594074.1\|1199535_1200537_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_000810136.1\|1200641_1200833_-	DUF3896 family protein	NA	NA	NA	NA
WP_001168161.1\|1201010_1202474_+	flavin monoamine oxidase family protein	A0A2K9L3H9	Tupanvirus	4.6e-12	20.6
WP_001068752.1\|1202558_1203143_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000442814.1\|1203166_1204069_-	aldo/keto reductase	A0A1V0SDE7	Indivirus	1.2e-10	25.6
WP_000613433.1\|1204234_1205185_+	GTP-binding protein	NA	NA	NA	NA
WP_001048672.1\|1205321_1205792_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001126163.1\|1205929_1206880_-	zinc ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000540935.1\|1207144_1207294_+	hypothetical protein	NA	NA	NA	NA
WP_001042747.1\|1207410_1208070_+	oxidoreductase	NA	NA	NA	NA
WP_000555702.1\|1208099_1209137_-	NADPH dehydrogenase NamA	NA	NA	NA	NA
WP_000283902.1\|1209270_1209723_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.6e-27	42.3
WP_000388938.1\|1209748_1210747_+	DUF2628 domain-containing protein	NA	NA	NA	NA
WP_000824261.1\|1210818_1212480_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000911702.1\|1212539_1212956_+	FosB/FosD family fosfomycin resistance bacillithiol transferase	Q2LI91	Bacillus_phage	4.0e-38	62.4
WP_000543131.1\|1212969_1213512_+	short-chain dehydrogenase	NA	NA	NA	NA
WP_000859186.1\|1213528_1214140_+	phosphoserine phosphatase 1	NA	NA	NA	NA
WP_000817489.1\|1214186_1214777_-	hypothetical protein	NA	NA	NA	NA
WP_000938007.1\|1214958_1216035_+\|coat	spore coat protein CotH	NA	NA	NA	NA
WP_000153581.1\|1216139_1216757_+	NUDIX hydrolase	NA	NA	NA	NA
WP_000880689.1\|1216861_1217464_+	DedA family protein	NA	NA	NA	NA
WP_015000401.1\|1217560_1218940_+	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_000933700.1\|1219124_1220066_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_000418718.1\|1220264_1221161_+	permease	NA	NA	NA	NA
WP_000488051.1\|1221164_1222034_+	TIGR03943 family protein	NA	NA	NA	NA
WP_000141169.1\|1222230_1222737_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_000505094.1\|1222863_1222950_-	YjcZ family sporulation protein	NA	NA	NA	NA
WP_043322900.1\|1223110_1224295_+	cardiolipin synthase	NA	NA	NA	NA
WP_000340530.1\|1224325_1224796_+\|coat	spore coat protein	NA	NA	NA	NA

DBSCAN-SWA_2

1447881 : 1457517

Bacillus_phage(54.55%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000491233.1\|1447881_1448235_-	helix-turn-helix transcriptional regulator	A0A0U3SD25	Bacillus_phage	2.8e-48	86.2
WP_000854270.1\|1448452_1448644_+	helix-turn-helix transcriptional regulator	A0A0U3SLC2	Bacillus_phage	7.0e-22	85.2
WP_000151195.1\|1448685_1448955_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_187292044.1\|1448965_1449136_+	hypothetical protein	NA	NA	NA	NA
WP_187292043.1\|1449138_1449453_+	hypothetical protein	H0USU0	Bacillus_phage	1.5e-29	66.7
WP_000892409.1\|1449453_1449675_+	hypothetical protein	NA	NA	NA	NA
WP_001148172.1\|1449753_1450689_+	YqaJ viral recombinase family protein	S6C475	Thermus_phage	2.2e-100	58.8
WP_000224753.1\|1450704_1451511_+	recombination protein RecT	S6AVW6	Thermus_phage	3.5e-94	65.4
WP_000525984.1\|1451682_1452645_+	DnaD domain protein	H0USU2	Bacillus_phage	2.5e-43	52.4
WP_043322942.1\|1452775_1453408_+	ATP-binding protein	A0A0S2GLK2	Bacillus_phage	1.3e-56	51.4
WP_000334997.1\|1453413_1453602_+	hypothetical protein	NA	NA	NA	NA
WP_049820111.1\|1453776_1454091_+	hypothetical protein	A0A0A7AQW3	Bacillus_phage	3.1e-22	48.5
WP_000049839.1\|1454647_1455064_+	DUF1064 domain-containing protein	A0A2P1JTY5	Anoxybacillus_phage	1.4e-30	51.9
WP_000120344.1\|1455078_1455756_+	hypothetical protein	NA	NA	NA	NA
WP_000779203.1\|1455774_1456170_+	hypothetical protein	NA	NA	NA	NA
WP_001237530.1\|1456203_1456398_+	XtrA/YqaO family protein	A0A1L2JY31	Aeribacillus_phage	7.4e-11	54.5
WP_000595938.1\|1456397_1457039_+	hypothetical protein	NA	NA	NA	NA
WP_001072807.1\|1457139_1457517_+	hypothetical protein	A0A2H4J748	uncultured_Caudovirales_phage	1.8e-21	47.2

DBSCAN-SWA_3

2892911 : 3006390

110

Bacillus_phage(44.23%)

tRNA,portal,protease,terminase,head,coat,tail,integrase,capsid

attL 2947413:2947428|attR 3011608:3011623

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001288802.1\|2892911_2893454_-\|coat	outer spore coat protein CotE	NA	NA	NA	NA
WP_000870465.1\|2893580_2894012_-	RicAFT regulatory complex protein RicA family protein	NA	NA	NA	NA
WP_001005380.1\|2894015_2895545_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_000190161.1\|2895976_2896843_-	2-oxoacid:ferredoxin oxidoreductase subunit beta	NA	NA	NA	NA
WP_000625414.1\|2896829_2898587_-	2-oxoacid:acceptor oxidoreductase subunit alpha	NA	NA	NA	NA
WP_000688028.1\|2898814_2899738_-	dipeptidase	NA	NA	NA	NA
WP_000404341.1\|2899796_2900057_-	stage V sporulation protein SpoVS	J9PTX7	Bacillus_phage	8.4e-10	43.8
WP_001221099.1\|2900206_2901001_-	TIGR00282 family metallophosphoesterase	NA	NA	NA	NA
WP_000204714.1\|2901148_2902714_-	ribonuclease Y	NA	NA	NA	NA
WP_001115378.1\|2903197_2903623_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	6.0e-45	63.9
WP_000301533.1\|2903888_2904512_-	hypothetical protein	NA	NA	NA	NA
WP_000990728.1\|2905362_2906601_-	competence/damage-inducible protein CinA	NA	NA	NA	NA
WP_001052980.1\|2906621_2907200_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_000137457.1\|2907263_2908178_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000574107.1\|2908199_2908985_-	DUF3388 domain-containing protein	NA	NA	NA	NA
WP_000114447.1\|2909123_2909372_-	DUF3243 domain-containing protein	NA	NA	NA	NA
WP_000759614.1\|2909447_2910161_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_000411963.1\|2910261_2911548_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	3.4e-11	29.4
WP_000772425.1\|2911548_2912823_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.0e-55	30.0
WP_000008852.1\|2913032_2913992_-	ABC transporter permease	NA	NA	NA	NA
WP_001085263.1\|2913992_2915051_-	ABC transporter permease	NA	NA	NA	NA
WP_000456933.1\|2915043_2916576_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	2.8e-12	28.6
WP_000725766.1\|2916694_2917780_-	BMP family ABC transporter substrate-binding protein	A0A0A7DN02	Lactobacillus_phage	5.8e-44	32.8
WP_000114182.1\|2917872_2918598_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_001118764.1\|2919137_2921522_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.0e-89	51.4
WP_000605019.1\|2921740_2921944_-	YlzJ-like family protein	NA	NA	NA	NA
WP_000139820.1\|2921940_2922690_-	translocation-enhancing protein TepA	NA	NA	NA	NA
WP_000823093.1\|2922793_2924464_-	ribonuclease J	NA	NA	NA	NA
WP_000564770.1\|2925067_2925946_-	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_000692465.1\|2925957_2927190_-	aspartate kinase	NA	NA	NA	NA
WP_000414844.1\|2927213_2928260_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_087991510.1\|2928410_2928626_-	dipicolinate synthase	NA	NA	NA	NA
WP_000459795.1\|2928702_2930043_-	hypothetical protein	NA	NA	NA	NA
WP_000713578.1\|2930627_2931125_+	hypothetical protein	A0A1B2APY6	Phage_Wrath	1.4e-64	75.8
WP_000856248.1\|2931653_2932301_+	hypothetical protein	NA	NA	NA	NA
WP_000272604.1\|2932423_2933689_+	Y-family DNA polymerase	O64031	Bacillus_phage	2.5e-107	48.3
WP_001057809.1\|2933685_2934027_+	YolD-like family protein	A0A1Q1PW34	Staphylococcus_phage	1.1e-06	33.3
WP_000913819.1\|2934235_2934733_+	hypothetical protein	NA	NA	NA	NA
WP_000939539.1\|2934996_2935500_+	hypothetical protein	NA	NA	NA	NA
WP_000939538.1\|2935992_2936484_+	hypothetical protein	NA	NA	NA	NA
WP_000751890.1\|2936535_2937600_-	N-acetylmuramoyl-L-alanine amidase	A0A0A7AQV3	Bacillus_phage	4.5e-190	90.1
WP_000461731.1\|2937596_2937836_-	hypothetical protein	A0A0A7AR38	Bacillus_phage	8.5e-33	93.7
WP_000398742.1\|2937835_2938072_-	hemolysin XhlA family protein	A0A2H4J382	uncultured_Caudovirales_phage	6.7e-14	84.6
WP_001067565.1\|2938193_2938592_-	hypothetical protein	A0A2H4JGF7	uncultured_Caudovirales_phage	5.7e-66	93.2
WP_000030428.1\|2938606_2943136_-\|tail	phage tail protein	A0A2H4JF18	uncultured_Caudovirales_phage	0.0e+00	78.5
WP_000094108.1\|2943132_2944590_-\|tail	phage tail family protein	A0A2H4JH21	uncultured_Caudovirales_phage	1.2e-265	90.3
WP_000918793.1\|2944630_2948251_-	hypothetical protein	A0A2H4JAI2	uncultured_Caudovirales_phage	8.1e-191	88.3
2947413:2947428	attL	NA	NA	NA	NA
WP_000415910.1\|2948482_2948845_-	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	1.1e-55	92.5
WP_001004909.1\|2948849_2949437_-\|tail	phage tail protein	A0A2H4JDV4	uncultured_Caudovirales_phage	7.1e-89	83.1
WP_000172100.1\|2949437_2949767_-	hypothetical protein	D2XR22	Bacillus_phage	7.6e-56	96.3
WP_015000873.1\|2950109_2950460_-\|head	phage head closure protein	A0A2H4JGG7	uncultured_Caudovirales_phage	3.0e-50	84.6
WP_000381899.1\|2950461_2950755_-	hypothetical protein	A0A2H4JG04	uncultured_Caudovirales_phage	3.5e-44	90.7
WP_000234881.1\|2950760_2951912_-\|capsid	phage major capsid protein	A0A2H4JHU0	uncultured_Caudovirales_phage	1.9e-207	95.8
WP_000216408.1\|2951915_2952698_-\|protease	Clp protease ClpP	R9TLM7	Paenibacillus_phage	5.6e-57	58.6
WP_000628341.1\|2952681_2953845_-\|portal	phage portal protein	A0A2H4JAJ1	uncultured_Caudovirales_phage	3.7e-182	81.5
WP_000621029.1\|2953854_2955522_-\|terminase	terminase large subunit	D2XR15	Bacillus_phage	5.2e-310	93.5
WP_000301149.1\|2955518_2955830_-\|terminase	P27 family phage terminase small subunit	D2XR14	Bacillus_phage	3.6e-47	97.1
WP_001008150.1\|2955956_2956292_-	HNH endonuclease	D2XR61	Bacillus_phage	2.1e-53	91.9
WP_000333208.1\|2956284_2956458_-	hypothetical protein	A0A1B1P8J7	Bacillus_phage	1.6e-20	84.2
WP_001072609.1\|2956463_2956691_-	hypothetical protein	D2XR60	Bacillus_phage	8.1e-25	80.6
WP_001294974.1\|2957605_2958301_+	hypothetical protein	NA	NA	NA	NA
WP_000743936.1\|2959078_2960065_+	hypothetical protein	A0A143FNS3	Bacillus_phage	4.3e-30	67.0
WP_000743935.1\|2960245_2961295_-	C40 family peptidase	A0A1S5SEZ8	Streptococcus_phage	1.8e-21	50.4
WP_001012141.1\|2961467_2962010_-\|integrase	site-specific integrase	W8CYP1	Bacillus_phage	4.0e-86	89.4
WP_000166149.1\|2961984_2962491_-	ArpU family transcriptional regulator	H0USV3	Bacillus_phage	1.2e-71	84.8
WP_000862383.1\|2962518_2962689_-	hypothetical protein	A0A1B0T6D0	Bacillus_phage	2.2e-11	80.4
WP_000960588.1\|2962805_2963003_-	hypothetical protein	NA	NA	NA	NA
WP_001113468.1\|2963219_2963384_+	hypothetical protein	A0A288WGN0	Bacillus_phage	5.7e-20	98.1
WP_000512851.1\|2964577_2964769_-	DUF3954 domain-containing protein	D2XR48	Bacillus_phage	1.9e-14	63.5
WP_001125995.1\|2964840_2965203_-	hypothetical protein	D2XR47	Bacillus_phage	2.2e-56	91.7
WP_000926802.1\|2965177_2965366_-	hypothetical protein	D2XR45	Bacillus_phage	6.3e-15	83.6
WP_000063896.1\|2965368_2966691_-	replicative DNA helicase	D2XR44	Bacillus_phage	6.9e-233	93.6
WP_000312132.1\|2966687_2967635_-	DnaD domain protein	D2XR43	Bacillus_phage	4.8e-87	62.1
WP_000215314.1\|2968385_2968607_-	hypothetical protein	NA	NA	NA	NA
WP_000537276.1\|2968620_2969208_-	hypothetical protein	D2XR41	Bacillus_phage	1.4e-73	68.7
WP_043322254.1\|2969298_2969547_-	hypothetical protein	NA	NA	NA	NA
WP_000405170.1\|2969601_2969793_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000172330.1\|2969963_2970374_+	helix-turn-helix transcriptional regulator	A0A2P1JU09	Anoxybacillus_phage	1.6e-31	52.4
WP_043323121.1\|2970386_2970830_+	ImmA/IrrE family metallo-endopeptidase	D2XR38	Bacillus_phage	2.9e-58	76.1
WP_000411164.1\|2970850_2971669_+	hypothetical protein	NA	NA	NA	NA
WP_000844783.1\|2971763_2973311_+	recombinase family protein	I3VYZ3	Thermoanaerobacterium_phage	3.9e-142	53.4
WP_000954741.1\|2973765_2974668_-	dipicolinic acid synthetase subunit A	NA	NA	NA	NA
WP_001239739.1\|2974835_2975087_-	YlmC/YmxH family sporulation protein	NA	NA	NA	NA
WP_000592990.1\|2975216_2976458_-	insulinase family protein	G3MBJ8	Bacillus_virus	7.5e-56	34.2
WP_000868234.1\|2976544_2977444_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_000076756.1\|2977595_2979734_-	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_001229392.1\|2979894_2980164_-	30S ribosomal protein S15	NA	NA	NA	NA
WP_000766713.1\|2980264_2981236_-	bifunctional riboflavin kinase/FAD synthetase	A0A1V0SD03	Indivirus	4.3e-06	33.6
WP_000399360.1\|2981279_2982203_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_000776439.1\|2982288_2982645_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_000036352.1\|2982938_2984999_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.4e-19	25.3
WP_001286525.1\|2985003_2985315_-	YlxQ family RNA-binding protein	NA	NA	NA	NA
WP_000071127.1\|2985315_2985588_-	YlxR family protein	NA	NA	NA	NA
WP_000102596.1\|2985599_2986706_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_000359095.1\|2986723_2987194_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_000060013.1\|2987527_2991829_-	PolC-type DNA polymerase III	A0A0A8WJ41	Clostridium_phage	5.3e-24	39.6
WP_000814296.1\|2991953_2993654_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_001090232.1\|2993763_2995020_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_000790354.1\|2995037_2996180_-	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_000813595.1\|2996203_2996995_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_000971308.1\|2997012_2997789_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	3.4e-22	43.1
WP_000531505.1\|2997874_2998432_-	ribosome recycling factor	NA	NA	NA	NA
WP_000042662.1\|2998434_2999157_-	UMP kinase	NA	NA	NA	NA
WP_001018579.1\|2999223_3000111_-	elongation factor Ts	NA	NA	NA	NA
WP_000111485.1\|3000214_3000916_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_000421291.1\|3001264_3002044_-	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_000550076.1\|3002121_3003513_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A173GFL6	Erwinia_phage	7.2e-47	29.7
WP_000526274.1\|3003535_3004078_-\|protease	ATP-dependent protease proteolytic subunit HslV	NA	NA	NA	NA
WP_001101234.1\|3004120_3005020_-	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	3.1e-35	31.9
WP_000212000.1\|3005085_3006390_-\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
3011608:3011623	attR	NA	NA	NA	NA

DBSCAN-SWA_4

3071449 : 3146059

Bacillus_phage(80.0%)

tRNA,portal,holin,protease,terminase,head,tail,integrase,capsid

attL 3103556:3103570|attR 3146099:3146113

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000455944.1\|3071449_3074215_-\|tRNA	isoleucine--tRNA ligase	A0A2K9L260	Tupanvirus	1.1e-86	28.0
WP_001131611.1\|3074562_3075069_-	septum site-determining protein DivIVA	NA	NA	NA	NA
WP_000029703.1\|3075158_3075926_-	RNA-binding protein	NA	NA	NA	NA
WP_000214326.1\|3075941_3076205_-	YggT family protein	NA	NA	NA	NA
WP_000119137.1\|3076211_3076682_-	cell division protein SepF	NA	NA	NA	NA
WP_000218001.1\|3076701_3077376_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_001209013.1\|3077372_3078191_-	peptidoglycan editing factor PgeF	NA	NA	NA	NA
WP_043322276.1\|3078309_3078594_-	YlmC/YmxH family sporulation protein	NA	NA	NA	NA
WP_000197755.1\|3078762_3079542_-	RNA polymerase sporulation sigma factor SigG	A0A0Y0AU18	Bacillus_phage	3.4e-46	43.9
WP_000976947.1\|3079699_3080419_-	RNA polymerase sporulation sigma factor SigE	A0A2H4JC68	uncultured_Caudovirales_phage	2.5e-19	42.9
WP_000261989.1\|3080438_3081356_-	sigma-E processing peptidase SpoIIGA	NA	NA	NA	NA
WP_000888977.1\|3081741_3082896_-	cell division protein FtsZ	NA	NA	NA	NA
WP_001087556.1\|3082935_3084243_-	cell division protein FtsA	NA	NA	NA	NA
WP_000798216.1\|3084644_3085415_-	cell division protein DivIB	NA	NA	NA	NA
WP_000437053.1\|3085513_3086419_-	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_001265419.1\|3086481_3087576_-	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_000753526.1\|3087677_3088769_-	stage V sporulation protein E	NA	NA	NA	NA
WP_000860135.1\|3088859_3090212_-	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_000893064.1\|3090212_3091187_-	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_000766293.1\|3091209_3092685_-	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase	NA	NA	NA	NA
WP_001266241.1\|3092893_3094810_-	stage V sporulation protein D	NA	NA	NA	NA
WP_002093365.1\|3094891_3096991_-	penicillin-binding protein	NA	NA	NA	NA
WP_000182809.1\|3097063_3097426_-	cell division protein FtsL	NA	NA	NA	NA
WP_000472506.1\|3097441_3098374_-	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_000405027.1\|3098743_3100360_-	bacillithiol biosynthesis cysteine-adding enzyme BshC	NA	NA	NA	NA
WP_033661358.1\|3100439_3101324_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_000506686.1\|3101618_3102092_+	N-acetyltransferase	NA	NA	NA	NA
WP_000246459.1\|3102125_3102632_-	RsfA family transcriptional regulator	G3MB11	Bacillus_virus	3.9e-11	34.7
WP_001984764.1\|3102761_3102935_-	50S ribosomal protein L32	NA	NA	NA	NA
WP_000872142.1\|3102996_3103497_-	DUF177 domain-containing protein	NA	NA	NA	NA
3103556:3103570	attL	NA	NA	NA	NA
WP_001025812.1\|3103779_3104400_-	replication-relaxation family protein	H0USY2	Bacillus_phage	1.6e-94	80.1
WP_000891541.1\|3104341_3105523_-	cell division protein FtsK	H0USY1	Bacillus_phage	1.0e-187	82.4
WP_000170781.1\|3105638_3105821_-	hypothetical protein	Q2I8E2	Bacillus_phage	2.7e-23	93.3
WP_001267644.1\|3105823_3106126_-	hypothetical protein	Q2I8E3	Bacillus_phage	8.5e-46	91.0
WP_000340447.1\|3106285_3106480_+	helix-turn-helix domain-containing protein	A0A1B1P7S8	Bacillus_phage	4.1e-25	93.8
WP_000728659.1\|3106573_3107191_+	hypothetical protein	NA	NA	NA	NA
WP_000509865.1\|3107254_3108049_-	N-acetylmuramoyl-L-alanine amidase	D2XR33	Bacillus_phage	9.6e-105	68.3
WP_000002925.1\|3108116_3108611_-	hypothetical protein	NA	NA	NA	NA
WP_000375618.1\|3108610_3109036_-\|holin	phage holin family protein	A0A1B1P787	Bacillus_phage	1.6e-69	96.5
WP_000390483.1\|3109109_3109334_-	XpaF1 protein	A0A1B1P780	Bacillus_phage	8.5e-27	90.3
WP_000403082.1\|3109485_3109854_-	hypothetical protein	NA	NA	NA	NA
WP_001123596.1\|3109859_3111596_-	hypothetical protein	A0A1D6X866	Bacillus_phage	3.3e-09	26.3
WP_000301779.1\|3111604_3112693_-	hypothetical protein	U5J9M9	Bacillus_phage	5.0e-88	51.5
WP_043322286.1\|3112711_3114718_-\|tail	phage tail protein	A0A0U4JID8	Exiguobacterium_phage	7.6e-82	35.5
WP_000184668.1\|3114730_3115516_-\|tail	phage tail family protein	A0A2H4JBY6	uncultured_Caudovirales_phage	5.6e-73	53.2
WP_000896618.1\|3115512_3120543_-\|tail	phage tail tape measure protein	A0A1B1P7S6	Bacillus_phage	0.0e+00	85.0
WP_043323124.1\|3120558_3120699_-	hypothetical protein	A0A1B1P7R9	Bacillus_phage	1.6e-15	89.1
WP_142333337.1\|3120716_3121148_-	hypothetical protein	A0A1B1P7S9	Bacillus_phage	2.1e-53	81.1
WP_000997085.1\|3121183_3121756_-\|tail	tail protein	A0A1B1P7S4	Bacillus_phage	7.2e-86	78.4
WP_001211419.1\|3121767_3122127_-	hypothetical protein	A0A1B1P7S7	Bacillus_phage	4.8e-56	87.4
WP_000852718.1\|3122123_3122561_-	HK97 gp10 family phage protein	A0A1B1P7R6	Bacillus_phage	2.2e-71	93.1
WP_001069941.1\|3122548_3122896_-\|head	phage head closure protein	A0A1B1P7T4	Bacillus_phage	9.4e-57	92.2
WP_000891457.1\|3122882_3123158_-\|head,tail	phage gp6-like head-tail connector protein	A0A1B1P7Q8	Bacillus_phage	5.9e-38	91.2
WP_000272023.1\|3123166_3123367_-	fibronectin type III domain-containing protein	NA	NA	NA	NA
WP_000790812.1\|3123443_3124625_-\|capsid	phage major capsid protein	A0A1B1P7R4	Bacillus_phage	6.9e-200	91.6
WP_001107321.1\|3124624_3125377_-\|protease	Clp protease ClpP	A0A0U3U021	Bacillus_phage	7.9e-133	95.6
WP_000697138.1\|3125354_3126569_-\|portal	phage portal protein	A0A0U3SQF0	Bacillus_phage	2.4e-216	89.9
WP_000626165.1\|3126584_3128357_-\|terminase	terminase large subunit	A0A1B1P7R3	Bacillus_phage	0.0e+00	96.6
WP_000357496.1\|3128337_3128718_-\|terminase	phage terminase small subunit P27 family	A0A1B1P7R2	Bacillus_phage	1.3e-62	94.4
WP_001209623.1\|3128879_3129242_-	HNH endonuclease	A0A1B1P8D2	Bacillus_phage	9.5e-52	82.5
WP_000964489.1\|3129244_3129472_-	hypothetical protein	NA	NA	NA	NA
WP_148283617.1\|3129964_3130216_-	hypothetical protein	NA	NA	NA	NA
WP_043323127.1\|3130278_3130545_-	hypothetical protein	Q2I8B8	Bacillus_phage	1.5e-30	82.4
WP_001028525.1\|3131558_3132101_-\|integrase	site-specific integrase	A0A1B1P746	Bacillus_phage	2.5e-88	88.9
WP_001041479.1\|3132097_3132568_-	hypothetical protein	A0A1B1P744	Bacillus_phage	2.0e-49	63.2
WP_000866137.1\|3132588_3132759_-	hypothetical protein	A0A1B1P735	Bacillus_phage	5.1e-08	80.4
WP_001031142.1\|3132872_3133163_-	hypothetical protein	NA	NA	NA	NA
WP_000538740.1\|3133187_3133457_-	hypothetical protein	NA	NA	NA	NA
WP_000662513.1\|3133486_3133846_-	hypothetical protein	NA	NA	NA	NA
WP_015000902.1\|3133936_3134083_-	hypothetical protein	NA	NA	NA	NA
WP_000453752.1\|3134133_3134367_-	hypothetical protein	Q5YA92	Bacillus_phage	4.9e-09	42.6
WP_000873540.1\|3134399_3134852_-	hypothetical protein	NA	NA	NA	NA
WP_000438094.1\|3134890_3135313_-	hypothetical protein	A0A2H4J3B9	uncultured_Caudovirales_phage	1.5e-08	75.0
WP_000533093.1\|3135476_3135932_-	hypothetical protein	NA	NA	NA	NA
WP_000288162.1\|3136118_3136547_-	hypothetical protein	NA	NA	NA	NA
WP_000121197.1\|3136531_3136735_-	hypothetical protein	NA	NA	NA	NA
WP_000077268.1\|3136769_3137237_-	hypothetical protein	NA	NA	NA	NA
WP_000675888.1\|3137270_3137747_-	hypothetical protein	A0A288WFT9	Bacillus_phage	6.4e-64	68.2
WP_015000905.1\|3137750_3138266_-	dUTP diphosphatase	R9TQ23	Paenibacillus_phage	1.0e-27	43.9
WP_001272170.1\|3138286_3138760_-	hypothetical protein	A0A1B1P7W1	Bacillus_phage	2.2e-08	42.5
WP_000711468.1\|3138785_3138950_-	DUF3954 domain-containing protein	A0A1B1P7U5	Bacillus_phage	1.3e-11	63.5
WP_001125958.1\|3138968_3139328_-	hypothetical protein	A0A1B1P7A1	Bacillus_phage	2.9e-32	54.2
WP_000799037.1\|3139320_3139599_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	5.1e-13	64.4
WP_001060923.1\|3139602_3140628_-	DnaD domain protein	W8CYG5	Bacillus_phage	9.0e-55	42.3
WP_015000907.1\|3140685_3140850_-	hypothetical protein	A0A1B0T6C1	Bacillus_phage	8.7e-13	70.4
WP_000284335.1\|3140906_3141107_-	helix-turn-helix domain-containing protein	A0A0U4IIS1	Bacillus_phage	1.4e-07	50.0
WP_000935434.1\|3141217_3141412_-	helix-turn-helix transcriptional regulator	A0A0A7AQV9	Bacillus_phage	1.4e-06	45.2
WP_001021262.1\|3141580_3141937_+	helix-turn-helix transcriptional regulator	A0A0P0IZG9	Lactobacillus_phage	5.4e-15	44.6
WP_000908626.1\|3141933_3142116_-	hypothetical protein	NA	NA	NA	NA
WP_000720667.1\|3142258_3142393_-	hypothetical protein	NA	NA	NA	NA
WP_001165427.1\|3142394_3143540_-	hypothetical protein	H0UST6	Bacillus_phage	5.3e-56	33.0
WP_001091276.1\|3143977_3144322_+	helix-turn-helix transcriptional regulator	I3VYY8	Thermoanaerobacterium_phage	2.2e-05	32.9
WP_000833168.1\|3144409_3144598_-	hypothetical protein	NA	NA	NA	NA
WP_000503721.1\|3144616_3144766_-	hypothetical protein	NA	NA	NA	NA
WP_000323189.1\|3144928_3146059_+\|integrase	site-specific integrase	A0A0U4JNS1	Bacillus_phage	1.2e-63	37.7
3146099:3146113	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3701133 : 3708806

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000221075.1\|3701133_3702057_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.3e-46	43.1
WP_000183219.1\|3702183_3703119_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	6.3e-23	26.3
WP_000018038.1\|3703120_3703813_-	response regulator transcription factor	B5LWA6	Feldmannia_species_virus	1.4e-06	28.8
WP_001293580.1\|3703981_3704155_+	hypothetical protein	NA	NA	NA	NA
WP_001014310.1\|3704155_3704350_+	YwbE family protein	NA	NA	NA	NA
WP_001255937.1\|3704389_3705589_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	1.9e-72	41.3
WP_000587821.1\|3705875_3706199_+	heme oxygenase	NA	NA	NA	NA
WP_015001005.1\|3706265_3707030_-	class B sortase	NA	NA	NA	NA
WP_000403759.1\|3707062_3707833_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.7e-13	28.6
WP_001036848.1\|3707822_3708806_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	27.2

DBSCAN-SWA_6

4932251 : 4940626

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000610752.1\|4932251_4933559_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.9e-21	25.5
WP_001170546.1\|4933647_4934367_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	3.0e-49	44.3
WP_000278820.1\|4934359_4934614_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666770.1\|4934610_4935294_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_000055551.1\|4935277_4937497_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	3.7e-162	41.2
WP_000879031.1\|4937481_4938897_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	7.3e-55	35.4
WP_001262428.1\|4939001_4940042_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.2e-67	45.6
WP_000088571.1\|4940038_4940626_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.3e-26	35.8

DBSCAN-SWA_7

5098838 : 5143196

Bacillus_phage(58.33%)

portal,protease,terminase,head,tail,integrase,capsid

attL 5115106:5115121|attR 5129142:5129157

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000615219.1\|5098838_5100218_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	2.3e-85	38.3
WP_000679469.1\|5100278_5101403_-\|integrase	site-specific integrase	A0A1B0T6A8	Bacillus_phage	5.2e-189	86.1
WP_000970854.1\|5101578_5101737_+	hypothetical protein	A0A1B0T6B0	Bacillus_phage	1.1e-15	92.3
WP_000742855.1\|5102415_5103012_-	DUF4352 domain-containing protein	A0A1B1P898	Bacillus_phage	2.7e-43	70.4
WP_001215551.1\|5103420_5103765_-	helix-turn-helix transcriptional regulator	A0A1B1P888	Bacillus_phage	1.5e-33	63.1
WP_001174513.1\|5104260_5105424_+	hypothetical protein	NA	NA	NA	NA
WP_000722888.1\|5105430_5105586_+	hypothetical protein	A0A1B1P8B4	Bacillus_phage	6.5e-10	66.7
WP_001213812.1\|5105886_5106237_-	helix-turn-helix transcriptional regulator	A0A142LP08	Marinitoga_camini_virus	1.7e-05	43.9
WP_000575563.1\|5106503_5106707_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001072754.1\|5106788_5107583_+	phage antirepressor KilAC domain-containing protein	R4IFK0	Staphylococcus_phage	2.5e-76	55.5
WP_000798610.1\|5107649_5108000_+	helix-turn-helix domain-containing protein	A0A1B0T6C2	Bacillus_phage	6.8e-55	90.5
WP_000969631.1\|5107996_5108164_+	hypothetical protein	A0A0U3B230	Bacillus_phage	5.6e-15	72.2
WP_000364138.1\|5108193_5108370_+	hypothetical protein	A0A1B1P7U0	Bacillus_phage	4.5e-23	87.9
WP_000005657.1\|5108375_5109263_+	phage replisome organizer N-terminal domain-containing protein	V9QKF6	Oenococcus_phage	7.8e-55	45.1
WP_001148325.1\|5109198_5110068_+	ATP-binding protein	A0A1B0T6C3	Bacillus_phage	5.8e-103	71.9
WP_000332468.1\|5110070_5110265_+	hypothetical protein	A0A1B1P7U7	Bacillus_phage	1.3e-23	84.4
WP_000805169.1\|5110290_5110464_+	DUF3954 domain-containing protein	A0A1B1P7U5	Bacillus_phage	1.3e-22	89.5
WP_000811697.1\|5110478_5110733_+	hypothetical protein	A0A0U3SU43	Bacillus_phage	6.7e-36	84.5
WP_015001249.1\|5110740_5111205_+	hypothetical protein	A0A2H4J8I5	uncultured_Caudovirales_phage	7.5e-17	35.4
WP_000665840.1\|5111231_5111444_+	hypothetical protein	A0A1B0T6B5	Bacillus_phage	1.5e-25	95.2
WP_000360135.1\|5111481_5111736_+	hypothetical protein	NA	NA	NA	NA
WP_001025407.1\|5111772_5111997_+	hypothetical protein	A0A0S2GLC6	Bacillus_phage	1.3e-22	67.6
WP_000784377.1\|5111993_5112293_-	hypothetical protein	W8CYG6	Bacillus_phage	2.8e-25	62.6
WP_000668246.1\|5112442_5112583_+	hypothetical protein	NA	NA	NA	NA
WP_000124017.1\|5112620_5112989_+	hypothetical protein	NA	NA	NA	NA
WP_000339165.1\|5113008_5113251_+	hypothetical protein	A0A1B1P7A3	Bacillus_phage	8.4e-28	70.5
WP_000021719.1\|5113284_5113590_+	hypothetical protein	NA	NA	NA	NA
WP_000424484.1\|5114541_5114706_+	hypothetical protein	A0A0A7AQ96	Bacillus_phage	3.8e-16	75.5
5115106:5115121	attL	NA	NA	NA	NA
WP_001245639.1\|5115128_5115950_-	hypothetical protein	NA	NA	NA	NA
WP_000666332.1\|5117043_5117790_+	hypothetical protein	NA	NA	NA	NA
WP_000497527.1\|5117812_5118994_+	ImmA/IrrE family metallo-endopeptidase	A0A0A7RTT7	Clostridium_phage	4.4e-37	29.0
WP_000166146.1\|5119285_5119774_+	ArpU family transcriptional regulator	A0A1B0T6C9	Bacillus_phage	8.3e-83	95.7
WP_001012127.1\|5119770_5120313_+\|integrase	site-specific integrase	A0A1B0T6D2	Bacillus_phage	1.4e-94	97.8
WP_000930964.1\|5120528_5120753_+	hypothetical protein	H0USV5	Bacillus_phage	1.3e-30	91.9
WP_001033082.1\|5121201_5121390_+	hypothetical protein	NA	NA	NA	NA
WP_000347594.1\|5121456_5122332_+	hypothetical protein	NA	NA	NA	NA
WP_000452083.1\|5122384_5122627_+	hypothetical protein	A0A288WG15	Bacillus_phage	4.3e-24	66.2
WP_000378695.1\|5122642_5122906_+	hypothetical protein	NA	NA	NA	NA
WP_001241249.1\|5122925_5123297_+	hypothetical protein	NA	NA	NA	NA
WP_000666405.1\|5123262_5123598_+	HNH endonuclease	D2XR61	Bacillus_phage	3.8e-55	93.7
WP_000301148.1\|5123721_5124033_+\|terminase	P27 family phage terminase small subunit	D2XR14	Bacillus_phage	3.8e-41	89.2
WP_000595322.1\|5124029_5125697_+\|terminase	terminase large subunit	D2XR15	Bacillus_phage	7.8e-290	86.8
WP_049820091.1\|5125762_5126872_+\|portal	phage portal protein	A0A2H4JAJ1	uncultured_Caudovirales_phage	3.1e-186	88.9
WP_000812150.1\|5126852_5127620_+\|protease	Clp protease ClpP	A0A2H4JC91	uncultured_Caudovirales_phage	4.2e-105	94.9
WP_000152781.1\|5127639_5128803_+\|capsid	phage major capsid protein	A0A2H4JH29	uncultured_Caudovirales_phage	4.6e-188	86.3
WP_000361978.1\|5128815_5129109_+	hypothetical protein	A0A2H4JG04	uncultured_Caudovirales_phage	9.8e-39	80.4
WP_043322706.1\|5129110_5129464_+\|head	phage head closure protein	A0A2H4JGG7	uncultured_Caudovirales_phage	2.3e-58	94.9
5129142:5129157	attR	NA	NA	NA	NA
WP_000997552.1\|5129465_5129810_+	HK97 gp10 family phage protein	A0A2H4JAH8	uncultured_Caudovirales_phage	3.3e-54	93.8
WP_000176455.1\|5129806_5130145_+	hypothetical protein	D2XR22	Bacillus_phage	4.3e-46	85.5
WP_000829684.1\|5130145_5130718_+\|tail	phage tail protein	A0A0U4JWV5	Exiguobacterium_phage	5.5e-54	57.4
WP_000751343.1\|5130722_5131085_+	hypothetical protein	A0A2H4JAG8	uncultured_Caudovirales_phage	5.4e-31	55.0
WP_000918776.1\|5131326_5135283_+	hypothetical protein	D2XR25	Bacillus_phage	2.8e-144	71.1
WP_000059749.1\|5135279_5136089_+\|tail	phage tail family protein	A0A2H4J982	uncultured_Caudovirales_phage	9.9e-57	40.4
WP_000752639.1\|5136102_5138034_+	hypothetical protein	NA	NA	NA	NA
WP_001176103.1\|5138077_5140021_+\|tail	phage tail protein	A0A2H4JG80	uncultured_Caudovirales_phage	1.4e-160	59.7
WP_001193275.1\|5140058_5140505_+	hypothetical protein	A0A2H4J980	uncultured_Caudovirales_phage	1.1e-52	76.5
WP_000482991.1\|5140541_5141252_+	macro domain-containing protein	A0A0M4QWS3	Salmonella_phage	1.4e-35	45.0
WP_000390472.1\|5141361_5141586_+	XpaF1 protein	A0A1B1P780	Bacillus_phage	9.5e-26	87.5
WP_000398746.1\|5141659_5141896_+	hemolysin XhlA family protein	A0A2H4J382	uncultured_Caudovirales_phage	1.2e-15	88.5
WP_000461735.1\|5141895_5142135_+	hypothetical protein	A0A0A7AR38	Bacillus_phage	1.6e-31	91.1
WP_000751921.1\|5142131_5143196_+	N-acetylmuramoyl-L-alanine amidase	A0A2H4JAS1	uncultured_Caudovirales_phage	5.3e-191	91.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

6. NC_018687

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_018687_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018687_1

25312-25427

Orphan

Consensus_repeat	Method
GTAACCAAATTTGTTATCTTTAGAACCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018687_1

>merge|NC_018687|1|25312-25427|CRISPRCasFinder
GTAACCAAATTTGTTATCTTTAGAACCACTTTTGTTATAGATAGATAACCAAATTTGTTATCTTTAGAACCATTCTTGTTATAGATAGGTAACCAAATTTGTTATCTTTAAAACCA

>NC_018687|1|1|25312-25427|CRISPRCasFinder
GTAACCAAATTTGTTATCTTTAGAACCA	CTTTTGTTATAGATAGATAACCAAATTTGTTATCTTTAGAACCATTCTTGTTATAGATAG
GTAACCAAATTTGTTATCTTTAAAACCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018687.1\|WP_000920048.1\|13844_16130_-\|Cys-Gln-thioester-bond-forming-surface-protein	unknown	unknown	gnl\|CDD\|227268
NC_018687.1\|WP_043324601.1\|22475_23582_-\|histidine-kinase	unknown	unknown	gnl\|CDD\|376220
NC_018687.1\|WP_000371951.1\|36982_37243_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_000417526.1\|22096_22300_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_000924393.1\|16274_16475_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_018687.1\|WP_001020341.1\|16672_17194_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
NC_018687.1\|WP_000152452.1\|31023_31209_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_001017153.1\|30725_31022_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_001273108.1\|26027_29276_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_014990503.1\|21199_21640_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_001040601.1\|35980_36313_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_187292049.1\|33171_35178_+\|pesticidal-protein	unknown	unknown	gnl\|CDD\|271151
NC_018687.1\|WP_001129777.1\|29790_30573_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_000451649.1\|29467_29632_-\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_000945858.1\|39588_40191_+\|replication-relaxation-family-protein	unknown	unknown	gnl\|CDD\|379384
NC_018687.1\|WP_000410158.1\|37643_38351_-\|IS6-family-transposase	unknown	unknown	gnl\|CDD\|225853
NC_018687.1\|WP_000026502.1\|23900_25112_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
NC_018687.1\|WP_001158047.1\|19218_19782_+\|DUF3967-domain-containing-protein	unknown	unknown	gnl\|CDD\|133393
NC_018687.1\|WP_000671526.1\|20002_21193_+\|ParM/StbA-family-protein	unknown	unknown	gnl\|CDD\|212669
NC_018687.1\|WP_001289503.1\|13242_13701_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_018687.1\|WP_000920048.1\|13844_16130_-\|Cys-Gln-thioester-bond-forming-surface-protein	gnl\|CDD\|227268	COG4932, COG4932, Predicted outer membrane protein [Cell envelope biogenesis, outer membrane].	6.6089e-56
NC_018687.1\|WP_043324601.1\|22475_23582_-\|histidine-kinase	gnl\|CDD\|376220	pfam18801, RapH_N, response regulator aspartate phosphatase H, N terminal. Rap proteins consist of a N-terminal 3-helix bundle and a tetratricopeptide domain. This entry represents the conserved region of the C-terminal bundle.	7.27287e-12
NC_018687.1\|WP_187292049.1\|33171_35178_+\|pesticidal-protein	gnl\|CDD\|271151	cd04085, delta_endotoxin_C, delta-endotoxin C-terminal domain may be associated with carbohydrate binding functionality. Delta-endotoxin C-terminal domain (delta endotoxin domain III) is part of the activated region of delta endotoxins, which are insecticidal toxins produced during sporulation by Bacillus species of bacteria. The activated endotoxin binds to the gut epithelium and causes cell lysis leading to death. This activated region of the delta endotoxin is composed of three structural domains. The N-terminal helical domain (I) is involved in membrane insertion and pore formation, while the second and third domains (II and III) are involved in receptor binding. Domain III structurally resembles the carbohydrate binding domain 6 (CBM6) and it is possible that insect specificity is determined by protein-protein or protein-carbohydrate interactions mediated by both domains II and III of the toxin. Delta-endotoxins are of great interest for development of new bioinsecticides and in the control of mosquitoes.	1.14293e-33
NC_018687.1\|WP_000924393.1\|16274_16475_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.8911e-10
NC_018687.1\|WP_001020341.1\|16672_17194_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.03878e-09
NC_018687.1\|WP_000945858.1\|39588_40191_+\|replication-relaxation-family-protein	gnl\|CDD\|379384	pfam13814, Replic_Relax, Replication-relaxation. This family includes proteins which are essential for plasmid replication and plasmid DNA relaxation.	7.7993e-11
NC_018687.1\|WP_000410158.1\|37643_38351_-\|IS6-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	8.84856e-68
NC_018687.1\|WP_000026502.1\|23900_25112_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	3.8679e-59
NC_018687.1\|WP_001158047.1\|19218_19782_+\|DUF3967-domain-containing-protein	gnl\|CDD\|133393	cd04765, HTH_MlrA-like_sg2, Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators. Putative helix-turn-helix (HTH) MlrA-like transcription regulators (subgroup 2), N-terminal domain. The MlrA protein, also known as YehV, has been shown to control cell-cell aggregation by co-regulating the expression of curli and extracellular matrix production in Escherichia coli and Salmonella typhimurium. These proteins belong to the MerR superfamily of transcription regulators that promote expression of several stress regulon genes by reconfiguring the spacer between the -35 and -10 promoter elements. Their conserved N-terminal domains contain predicted HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	3.22611e-05
NC_018687.1\|WP_000671526.1\|20002_21193_+\|ParM/StbA-family-protein	gnl\|CDD\|212669	cd10227, ParM_like, Plasmid segregation protein ParM and similar proteins. ParM is a plasmid-encoded bacterial homolog of actin, which polymerizes into filaments similar to F-actin, and plays a vital role in plasmid segregation. ParM filaments segregate plasmids paired at midcell into the individual daughter cells. This subfamily also contains Thermoplasma acidophilum Ta0583, an active ATPase at physiological temperatures, which has a propensity to form filaments.	6.62308e-43

>NC_018687.1|WP_000026502.1|23900_25112_-|replication-initiation-protein
MSINQDLQIKENNIVSKSNTLIEANSRLNLVEQKMLLCLASNIEPNDRDFKTYTFPIKQFHDLLGLNGSTKYTELSKITKELLSKVIEIRAGEELIQVSWLSSAIYNRNKGTIDMRFDPLLKPFLLELSSKFTSYRLANVVKLKSTYAIRIYELLKQYEDLKERTISLENLRYYLDAMDVYPNYANFKQRVLKPSQKELNQKTDISFEFEEIKLGRKVQKIRFIIRAQKKKDSDMVHFEKKLDKFQQPNTFEQKIKRFEERCKEKVFPKVFEKWAAHKEIVLEIIEDIRFRSDIDSPIGYVEFILNSRLKELSDKQISHESIQNEDESNNTLLEIDTIIDSVITKYSTSTGTVATFLVKDTTIEELVKVVALEEAEAIWKEKETFVMDKIYEFIKKNRSKKRY
>NC_018687.1|WP_043324601.1|22475_23582_-|histidine-kinase
MNVHVKGNEQVIQTLNEWYFKIRARDLDAAISLKDKIDLVINEYKEEKILMLHYYLIDFRHNYLLNNLGISTDSFDIIETFDIPQDNSLTYYYHFFKAIYYNAIGNYQSSQKFYDKAESLLKYINNELEIAEFHYMLGYKFYETYKGFLALQELSKAKGIFSKYAECENNVAFCNNLLGLTYADLDEFELANKYYTLALNAFKNIKEETFILMVKQNIALMYAKQDRPDLAIQFLSEVNKKMLNNYKALFVEAREYVKLLEKDVACERIERGINICKNLGIEEYLHHFRILQALNDDVDASKLEIIILEGVEYFEKQKMTEYTKEYQEHLAHKYYEQKNYLKSCEYFELSRKTKNIFKKGDLNEETTS
>NC_018687.1|WP_000417526.1|22096_22300_+|hypothetical-protein
MEKYPVEFTIISPNSEVYAPDIVYITANTPDAAIKQVEKEIESRMGKYYTFKVKISIQNEEEQLSLF
>NC_018687.1|WP_014990503.1|21199_21640_+|hypothetical-protein
MMAKPKAIQIPLSEKMRQRCPELFVWIESQENPNEATRKVLEHFIALYGTQSVDNEEIKLGMAKDLLSAKGMLQGDIPRGLPSKSPLTYKQPEEGNVIEEVESLIVNANEDNQPRNVHIEKSKEKTQEYPVNKPIKRNIDINKWTN
>NC_018687.1|WP_000671526.1|20002_21193_+|ParM/StbA-family-protein
MKFNYFVEDDNGNSEKKITINGEMMKFPNTYSYVYKEPVPQDKKIEELVHGLIHNMDVTVNSSALKGQVSQRVFVGERAIRSGEDLQNLNIKSNRGKHRQDTTIMTTVSAIACRSVQDMFKDQNSIEEGTNIEAIVSMVTALPASEWTKEKAKQLSERFTNSSHHVTVTVGDLRVYVTLKFEKVIVVQEGTIALFALIEDGNGNYRNDDIFNEFKETYDMKDITGEYFQEKRLLHIDIGDGTTEYVVTKGYDYDNDHSSGERHGIGHAIERAKKDFEDEWGFSIERQEFAGYLKEEHPKYYEDAKKFLARAKFNLADEVLDTAETKLQDLKYDVEVVVVYGGGSIQLKENLFEDLKEICDSKKIKILWIDAKNATEMNVKGMTVFSSIAFQKEQVK
>NC_018687.1|WP_001158047.1|19218_19782_+|DUF3967-domain-containing-protein
MQERSFWTKDVAERLEIGTSTLRKWCIALEQAQYSFVKGAKNSRAFVAKDIKVLEQMKKLIQEAGMSIEGAVKVVLSVPSAEVETDNDLEDDNRTPSVLSENVMNLPKGFIEQLLQEQILLKEKIQQLERIEIMNAERLERMENRYNERDNLLLTHVREIQETKQLLVASQNKQKEKKWWEFWKKHI
>NC_018687.1|WP_001020341.1|16672_17194_+|helix-turn-helix-domain-containing-protein
MNIFSERLRKLRQERSWSMKELGEKLSEVVGSSFSSASVSNWEKKGSEPPYNILAALAQIFDVSADYLIGISDTATLNNEAPTEKIEHKQDIINNVELYLTISEHEKKQDIYAKVKELHQEILLLPDEKQERLEKELTEYLRFFGYKYDQLHIDFVNFTNYLQHELQKKVSKY
>NC_018687.1|WP_000924393.1|16274_16475_-|helix-turn-helix-transcriptional-regulator
MLLIERQSKDYSLTQLGQKVNIKPQVLHAIEKGKTSVNSERAEKIAKFFNKPVEYFFIPTYYRVRE
>NC_018687.1|WP_000920048.1|13844_16130_-|Cys-Gln-thioester-bond-forming-surface-protein
MLKRSYQTLLIAMSMLLIVLNFVFPLTKASAEVINHEKYEMDWSFSPMYGKNLRTELLKNTNGQIAYCLTYGKLSPNGNDLPEMGRTDDIVYRVLLNGYPQKSPEELGVSNWKEAHYATQLSVWTALGQIDINEVQHRNGNVAKAAKAIIGGANASQETQDLYMNVTPTDNQEAKLNGEYFETTVYQIKSNAKNGVFTVQLANAPNGTKVVSTKGEAKQQFNLGEQFRILIPKSSQTGNFSLKVTSNLSNLQAVAYQGTDKVQDATVLLEKNEEKVSTDLQVNWKSLGGLKVVKVGEQKELLQGAVFEVMNSANQKVSTMTTNEQGSASLSGLEIGTYTLKEVKSPTGYVLNGQSQQIEVKTGEVATITVQNTKVKGNMEIKKLSDSGKTLPKVEFTVYTAEGKEITKVTTNEQGIAQVKDLPYGKYYFVETKGVEGYLLNQTKYPFEIKEQGKTLTFTVENKEVKGNVQLLKVDGENPDKKLEGAVFILQDSKGKKISEHKSDENGLIEVKDLPFGAYSFVEKQAPTGYVLTKESIPFSISEQGKTIMLTAKNKHITGELEISKVDIADGNNKLPNAEFTIFNEQGKEVAKGKTDENGIAKFKIPYGKYTYKETFAPDGYLLNEEIFSFEIKENGQIIKHTVKDQKKPTPPTPETPKPEQPEQPQKPEIPQKPEQPEAPQPQVPEQPKVTEKPVIPQLEKPQQIVMKPQLEQTPKKIETYLPTTGGKAENPYIKWIGLACVVLGLIGAVFAVRNRKKAQS
>NC_018687.1|WP_001289503.1|13242_13701_-|hypothetical-protein
MSEIHIGKMKNLGKPWEGVMRPKSAWLPEELMQAISIAQTVIKPLKQHDYWIESATKLLAGSILYLDQRHKNLYYLDVKKVIEFTEKMYESETKLIEVVNSLENEHPAYHIFHELGLYSKETRDAITITLLYILEKHQREKQGEQKEYFWFQ
>NC_018687.1|WP_001273108.1|26027_29276_+|hypothetical-protein
MSAIKIEDIYQEVLDGKRKQFPPYTWSEDINRNLVKRVIKYLVEIVLNWDDNMLKEGWNKKLIKKYKLDGAVCMIYRGSPYAMLNDAYPDRFKEWEFKMAPLNFWTKEKGLEALKWTIETKEKLTDEQLLQVYGTKWLTRHKIISPCAKFFNHSPYIMLNALYPGKFREWEMKHTPSNFWTKENALEALRWTIEEKEKLTEEQLFEVYNIKWLKQHNLAPACQIHWRNSPYSMLNALYPNRFKEWMFKVTPSNFWTKKKGLEALRWTIEEKEKLTNKELLCVYNQPWLNTHKLNTHKLNTPMKRYWNGSPYAFLNALYPGMFKEWDMKMAPVNFWTKGKGLEALKWTIEEKEKLTDEKLLRVYGTKWLQEHKLSTPCNKYWNASPYAMLNELYPGRFKEWELENVPTNFWTKEKSIEVIKWNIESKEKLIKENLIQIMNTEWLKMHRLITPFNKYWNGNIYAMLNELYPGDFKKWEMKKVSNNYWTKEITLKVIREKLQEKGNVSNEEFLQEYNMEWIKRNGLTTPLAMYWSNNPYNLLHDAYPARFTHEVIKAYKRIQQLRSIVPQDVELSHRSSNSVLTIEEIYQEVLNGKRDGFPYYVWSEGDKKLLARRVTKYLIEVILNWDTEEIKKGWSGKVIKKYKLNGMVTLVYNGSPYAMLNDLYPNRFKEWELSYTPSNFWTKETAIEALRWTIEEKEQLTGEQLLKVYSDKWLQEKRILTPCCKYWNCSPYAMLNELYPNRFKQWELKNVPTNFWTKEKALEALRWTIEEKERLIDEQLKKIYNIAWMKKQRLITPLMTYWNLSPYMMLNELYPGRFKEWEFSVVPRNFWTKEKGLEALRWTIEEKEKLTDGQLLQTFSNQWLVKHRLVTPLNKHWNNAYEMLNDLYPNRFKEWELQKVSKNFWTKEKGLEALRWTIEEKEKLTDEQLLRVYDITWMKKHGISMPVYEYWSNNPYLMLHDLYPNKFSKEVMKTYVSMRKWFKEFFETEGYSKMLNLVWENSYIHGDTFVFTHVKREEVIQFFYQIKGASSIESRYNELKGREEWYCTLSKWHPLVLKLKELGWKDTEDSINNLQNKCTPVN
>NC_018687.1|WP_000451649.1|29467_29632_-|hypothetical-protein
MEVFLEFLKEMIKAVIREITAHLFKKKFLDQRKTTLSSRRPKQKKKGGFRKYKR
>NC_018687.1|WP_001129777.1|29790_30573_+|hypothetical-protein
MAKSDIELSKQVKKHKLIDLTFNFEEANHYLQSVVQTKKLYQLLLLILISFILIYTPLWNFLYTNLFGETSKYVKAMLQSCFYTIPIAIPFFWIFRFDIQKIFKKFTLHQYKKTWWIALYIIFIIMFVALTVSTITSFEFATNQGFVGERKLILFRIFVLFIQLFGENLIFISLLLGCYKLLQYVTSHERTIIIISFLLASIIFGIFHLPTYNFNLIQCIFFIGIPALPHLIVFVKYQNAHMGYWVHLNYDLMLLVLVLL
>NC_018687.1|WP_001017153.1|30725_31022_+|hypothetical-protein
MNHYQMLYSTPYLYPSQMLKQMYNETNKEENVCAIRDHMLRYDVYLDRQYKFYYYLSQKIEEDLYGDEQAVSWNELLDEYQLFKDGKGNLSIKPKGWG
>NC_018687.1|WP_000152452.1|31023_31209_+|hypothetical-protein
MTIIGELGIVYGVTGASVLGIKFLKKKGFYLPGWLLRAGLKCLLIGTVWYVLMDILDVFLR
>NC_018687.1|WP_187292049.1|33171_35178_+|pesticidal-protein
MIQRIYLVLLTEILTILDTLLQIIRINHYKNWINMCQKNQQYGENLETFASADTIAGVSAGVIVVGTMLGAFAAPITAGLIISFGTLLPIFWKPGEDPKTVWQAFLKIGNRPFSSPVDQALIDLLSNKARSLESQFNDFQRYFDIWNNNKTPGNAGEVLRRFSSLDADIIRELEQLKGNYYITVLPGYAQVANWHLNLLRIAAFYYDQWASSSNLSIQSIYPEDYINDLQTCLTNCAIESGNKISSKYYKCVLKCRINEYINYCSKTYQEGLNILKNSSGLKWNEYNTYRREMTLNVLDLIAVFPNYDPDKYLISTKSQLTREIYTDALIDAFANAHFNINDIENSLTRPPGLVTWINRLDFYTGMFTKSVPGLTANGINYSFTNGNSNDSPIYGYRLSDDSSTPIQIPRNQYVYNMLITYLRDSPSVIQKIEFNLNNQQTRTYDTGLTLAPTYQSTINLSLPGKDRSFPPKFNNYTHFLSYVKTAPGDERPSSSRARNVCFGWMHFSVNDYDVLAGGYNTISNKIITQIPAVKARHLPLPSFVMPGPGHTGGNLVVLSTQIEFQCIVLNPVSYKIRMRYVAYSPNRSINLTVSIRSEIGNYQNIVPNISSTVQSPEDTKNPKYEHFQYLDISIPLELFGITNITITRSDSISNNTLIIDKIEFTPDV
>NC_018687.1|WP_001040601.1|35980_36313_+|hypothetical-protein
MAKEKKNSKQQQSDQPACTPNISAEVCVEADITIIPTVEAGTPVVHCVGVPSLETCADMGFTPSATGNCKFTISQVLCISIPISFGAETIAVPGTVACGHACNGPNCSTT
>NC_018687.1|WP_000371951.1|36982_37243_+|hypothetical-protein
MDQFRDKLMLGAIPIHQIDKNGIPLRQFDEVQYMGEQYIIIWHPMYGEFVASHCTGEFLPFNVLDKVEYTKNLKNYYSTKKKSFNI
>NC_018687.1|WP_000410158.1|37643_38351_-|IS6-family-transposase
MEKENLFKWKHYQPDIILLTVRWYLRYNLSFRDLVEMMEERGLSLSHTTIMRWVHQYGPELNERIPKHLKQTNDSWRVDETYIKIKGEKMYLYRAVDSKGSTLDFYLSNKRDAKAAKRFLKKTLASYHVTKPRVITVDGDKAYPVAIRELKNEKSIPHGMPLRVKKYLNNLIEQDHRFIKKRIWTMLGLKSLRTATKMIAGIEAMHMVKKGQLKLREQSVKNQNIFIQHLFGLNV
>NC_018687.1|WP_000945858.1|39588_40191_+|replication-relaxation-family-protein
MLRPRDKKIIQALQLFRCMSRDQIVKLFFSDVKNPITSANFVLKRLRREKHIDAYVDKQPYIYFPQPSIIKKNSQKIKHYLAIVDFYIDVCKHEYPTIFEVEKRYGSGYVQPDIFMVWQGRIFFVEIQLSRYSSELMKEKLNRYVNYFKSELWYRKKIEFNLNNLPFVWIISKNPYVIKDAKLQIIQTSNADKIFSNSSI

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Crispr_ID: NC_018687_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018687_2

73038-73142

Orphan

Consensus_repeat	Method
ATTCCGTTACGATCAACGTAATTACTATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018687_2

>merge|NC_018687|2|73038-73142|CRISPRCasFinder
ATTCCGTTACGATCAACGTAATTACTATGCGTAGTTGGAACAATAACGTCCCTTGTTTGATGATGTGATATCCTTGATTCCGTTACGATCAACGTAATTACTATG

>NC_018687|2|2|73038-73142|CRISPRCasFinder
ATTCCGTTACGATCAACGTAATTACTATG	CGTAGTTGGAACAATAACGTCCCTTGTTTGATGATGTGATATCCTTG
ATTCCGTTACGATCAACGTAATTACTATG

Protein	Signature genes	Signature genes Name	Protein_function
NC_018687.1\|WP_000197242.1\|56473_56740_-\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_000254349.1\|59153_59966_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_014990534.1\|86091_87615_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375474
NC_018687.1\|WP_000536091.1\|69936_70278_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_000360259.1\|80510_81494_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_000368918.1\|55201_55756_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_000702449.1\|68335_69244_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	unknown	unknown	gnl\|CDD\|224131
NC_018687.1\|WP_148283634.1\|64145_65585_-\|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein	unknown	unknown	gnl\|CDD\|176528
NC_018687.1\|WP_000197243.1\|54002_54275_-\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_001055929.1\|92634_94068_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_018687.1\|WP_014990527.1\|71638_73030_-\|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein	unknown	unknown	gnl\|CDD\|176528
NC_018687.1\|WP_080595736.1\|78224_78554_-\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|372646
NC_018687.1\|WP_000667332.1\|78994_80155_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NC_018687.1\|WP_000703245.1\|67023_68334_-\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223936
NC_018687.1\|WP_000495154.1\|74227_75880_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375474
NC_018687.1\|WP_001243455.1\|95832_96876_-\|Fic-family-protein	unknown	unknown	gnl\|CDD\|225718
NC_018687.1\|WP_000254348.1\|58193_59150_+\|hypothetical-protein	unknown	unknown	unknown
NC_018687.1\|WP_000806152.1\|75993_78057_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367738
NC_018687.1\|WP_148283635.1\|82899_84312_+\|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein	unknown	unknown	gnl\|CDD\|176528
NC_018687.1\|WP_000730235.1\|91273_92200_-\|ETX/MTX2-family-pore-forming-toxin	unknown	unknown	gnl\|CDD\|380793

Protein	Function_ID	Function_description	E-value
NC_018687.1\|WP_014990534.1\|86091_87615_-\|hypothetical-protein	gnl\|CDD\|375474	pfam17997, Cry1Ac_D5, Insecticidal delta-endotoxin CryIA(c) domain 5. This domain is found in the protoxins portion of insecticidal proteins (parasporins, or Cry proteins) such as those from Bacillus thuringiensis (Bt) Cry1Ac. The protoxin portion comprise a proteolytically labile C-terminal segment (sometimes referred to as the protoxin domain). This is domain V in Cry1Ac from B. thuringiensis. One of the four protoxin domains (D-IV through D-VII). Domains V and VII are beta-rolls (similar to D-II or D-III) that closely resemble carbohydrate-binding modules (CBM) found in sugar hydrolases, however, it is difficult to guess which particular carbohydrates (if any) may serve as their ligands because residues on the putative sugar-binding interfaces are conserved neither in sequence nor in local structure. Structural analysis indicate that there are putative disulfide crosslinking at the dimer interface mediated by cysteines within 783-823 region of this domain which together with other cysteines creates a three-dimensional network of cross-links across the crystal which may play a role in stabilizing mature Bt Cry1Ac.	9.13617e-68
NC_018687.1\|WP_000667332.1\|78994_80155_-\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	2.44312e-17
NC_018687.1\|WP_148283634.1\|64145_65585_-\|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein	gnl\|CDD\|176528	cd08586, PI-PLCc_BcPLC_like, Catalytic domain of Bacillus cereus phosphatidylinositol-specific phospholipases C and similar proteins. This subfamily corresponds to the catalytic domain present in Bacillus cereus phosphatidylinositol-specific phospholipase C (PI-PLC, EC 4.6.1.13) and its sequence homologs found in bacteria and eukaryota. Bacterial PI-PLCs participate in Ca2+-independent PI metabolism, hydrolyzing the membrane lipid phosphatidylinositol (PI) to produce phosphorylated myo-inositol and diacylglycerol (DAG). Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. Bacterial PI-PLCs contain a single TIM-barrel type catalytic domain. Their catalytic mechanism is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This family also includes some uncharacterized eukaryotic homologs, which contains a single TIM-barrel type catalytic domain, X domain. They are similar to bacterial PI-PLCs, and distinct from typical eukaryotic PI-PLCs, which have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains, and strictly require Ca2+ for their catalytic activities. The prototype of this family is Bacillus cereus PI-PLC, which has a moderate thermal stability and is active as a monomer.	7.82489e-81
NC_018687.1\|WP_001055929.1\|92634_94068_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.85054e-14
NC_018687.1\|WP_014990527.1\|71638_73030_-\|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein	gnl\|CDD\|176528	cd08586, PI-PLCc_BcPLC_like, Catalytic domain of Bacillus cereus phosphatidylinositol-specific phospholipases C and similar proteins. This subfamily corresponds to the catalytic domain present in Bacillus cereus phosphatidylinositol-specific phospholipase C (PI-PLC, EC 4.6.1.13) and its sequence homologs found in bacteria and eukaryota. Bacterial PI-PLCs participate in Ca2+-independent PI metabolism, hydrolyzing the membrane lipid phosphatidylinositol (PI) to produce phosphorylated myo-inositol and diacylglycerol (DAG). Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. Bacterial PI-PLCs contain a single TIM-barrel type catalytic domain. Their catalytic mechanism is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This family also includes some uncharacterized eukaryotic homologs, which contains a single TIM-barrel type catalytic domain, X domain. They are similar to bacterial PI-PLCs, and distinct from typical eukaryotic PI-PLCs, which have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains, and strictly require Ca2+ for their catalytic activities. The prototype of this family is Bacillus cereus PI-PLC, which has a moderate thermal stability and is active as a monomer.	6.03171e-86
NC_018687.1\|WP_000806152.1\|75993_78057_-\|hypothetical-protein	gnl\|CDD\|367738	pfam03944, Endotoxin_C, delta endotoxin. This family contains insecticidal toxins produced by Bacillus species of bacteria. During spore formation the bacteria produce crystals of this protein. When an insect ingests these proteins they are activated by proteolytic cleavage. The N-terminus is cleaved in all of the proteins and a C terminal extension is cleaved in some members. Once activated the endotoxin binds to the gut epithelium and causes cell lysis leading to death. This activated region of the delta endotoxin is composed of three structural domains. The N-terminal helical domain is involved in membrane insertion and pore formation. The second and third domains are involved in receptor binding.	4.63391e-41
NC_018687.1\|WP_000702449.1\|68335_69244_-\|UTP--glucose-1-phosphate-uridylyltransferase-GalU	gnl\|CDD\|224131	COG1210, GalU, UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane].	9.29324e-165
NC_018687.1\|WP_000703245.1\|67023_68334_-\|UDP-glucose/GDP-mannose-dehydrogenase-family-protein	gnl\|CDD\|223936	COG1004, Ugd, Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NC_018687.1\|WP_000495154.1\|74227_75880_-\|hypothetical-protein	gnl\|CDD\|375474	pfam17997, Cry1Ac_D5, Insecticidal delta-endotoxin CryIA(c) domain 5. This domain is found in the protoxins portion of insecticidal proteins (parasporins, or Cry proteins) such as those from Bacillus thuringiensis (Bt) Cry1Ac. The protoxin portion comprise a proteolytically labile C-terminal segment (sometimes referred to as the protoxin domain). This is domain V in Cry1Ac from B. thuringiensis. One of the four protoxin domains (D-IV through D-VII). Domains V and VII are beta-rolls (similar to D-II or D-III) that closely resemble carbohydrate-binding modules (CBM) found in sugar hydrolases, however, it is difficult to guess which particular carbohydrates (if any) may serve as their ligands because residues on the putative sugar-binding interfaces are conserved neither in sequence nor in local structure. Structural analysis indicate that there are putative disulfide crosslinking at the dimer interface mediated by cysteines within 783-823 region of this domain which together with other cysteines creates a three-dimensional network of cross-links across the crystal which may play a role in stabilizing mature Bt Cry1Ac.	6.00075e-68
NC_018687.1\|WP_001243455.1\|95832_96876_-\|Fic-family-protein	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	1.6666e-10
NC_018687.1\|WP_080595736.1\|78224_78554_-\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|372646	pfam13610, DDE_Tnp_IS240, DDE domain. This DDE domain is found in a wide variety of transposases including those found in IS240, IS26, IS6100 and IS26.	1.77597e-18
NC_018687.1\|WP_148283635.1\|82899_84312_+\|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein	gnl\|CDD\|176528	cd08586, PI-PLCc_BcPLC_like, Catalytic domain of Bacillus cereus phosphatidylinositol-specific phospholipases C and similar proteins. This subfamily corresponds to the catalytic domain present in Bacillus cereus phosphatidylinositol-specific phospholipase C (PI-PLC, EC 4.6.1.13) and its sequence homologs found in bacteria and eukaryota. Bacterial PI-PLCs participate in Ca2+-independent PI metabolism, hydrolyzing the membrane lipid phosphatidylinositol (PI) to produce phosphorylated myo-inositol and diacylglycerol (DAG). Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. Bacterial PI-PLCs contain a single TIM-barrel type catalytic domain. Their catalytic mechanism is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This family also includes some uncharacterized eukaryotic homologs, which contains a single TIM-barrel type catalytic domain, X domain. They are similar to bacterial PI-PLCs, and distinct from typical eukaryotic PI-PLCs, which have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains, and strictly require Ca2+ for their catalytic activities. The prototype of this family is Bacillus cereus PI-PLC, which has a moderate thermal stability and is active as a monomer.	2.6382e-87
NC_018687.1\|WP_000730235.1\|91273_92200_-\|ETX/MTX2-family-pore-forming-toxin	gnl\|CDD\|380793	cd20223, PFM_epsilon-toxin-like, pore-forming module of Clostridium perfringens epsilon-toxin and similar aerolysin-type beta-barrel pore-forming proteins. Clostridium perfringens epsilon-toxin is responsible for fatal enterotoxemia in ungulates. It forms a heptamer in the lipid rafts of Madin-Darby Canine Kidney (MDCK) cells, leading to cell death; its oligomer formation is induced by activation of neutral sphingomyelinase. This group also includes an insecticidal crystal protein Cry14-4 (encoded on plasmid pBMBt1 of Bacillus thuringiensis serovar darmstadiensis). Also included is pXO2-60 (a protein from the pathogenic pXO2 plasmid of Bacillus anthracis) which harbors a unique ubiquitin-like fold domain at the C-terminus of the aerolysin-like domain, and is involved in virulence. They belong to the aerolysin family of beta-pore-forming proteins (beta-PFPs). PFPs are generally secreted as water-soluble monomers, which upon binding to target lipid membranes, oligomerize and form transmembrane pores harmful to cells. Beta-PFPs form pores by transmembrane beta-barrels. Aerolysin-type beta-PFPs are believed to use an amphipathic beta-hairpin to form the beta-barrel, are found in all kingdoms of life and many are bacterial toxins. In addition to having a role in microbial infection, they have potential as biotechnological sensors and delivery systems. They share a similar monomeric architecture, with a variable membrane-binding domain and a structurally conserved pore-forming region. A significant portion of the monomeric subunit structure is re-organized to form the pore. Oligomers formed by members of the aerolysin family include: hepta- (aerolysin), octa- (Dln1), and nonameric oligomers (lysenin and monalysin).	3.28857e-29

>NC_018687.1|WP_014990527.1|71638_73030_-|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein
MDRSGFNVNRTVDYINTNWMANIPDSRRIGELSIPGTHGSMALHGGVAGAIGHIAINQTMDLTTQLNSGIRYIDIRCRHYHNNFAIHHGQIYQHAFFGPGVLEPVIRFLRQNPSETILMRIKEEYNPRGNTRTFSETFESFWNANQRYFWNLTSLNPTLGEVRGRIIVLQDFPGFNRNFGIGWGQLDIQDRWDVAGPNDIYNKWIAIRNHFHRIRNTGHLSINHLSGTGGFRLGGPTPWFLACGYRSRNNNSLLDVASSRPVLTGWLDFPRDRPTIGAVYWGGMNVLAAKRILDHRFTHTGIVAADFPGRGLIEGTIALNFPDIFMGSHQIASLFGHGTDVFDLNVGNSRVILYNNHFGNNQRWRFEFDRTWQVYRIFSVSHPNLLLTGSDNPSVGGPHYAFAASERPNWISQRWIVERGARGFKLRSMVNRNYVLTIRGSNLMVEPDTPFFIGNEEFTIRPI
>NC_018687.1|WP_000536091.1|69936_70278_+|hypothetical-protein
MGSYFYDNYEHGEKHDYFYDYDERRNYFYDYGERRKKESNRRDDYSFYSSICNIFKILKSGDDVDTLIINGKSHSVDAFVSFDEQTGIVTFVKDNGAVFIVGHDKVDAIIIDN
>NC_018687.1|WP_000702449.1|68335_69244_-|UTP--glucose-1-phosphate-uridylyltransferase-GalU
MKIRRAIIPAAGLGTRFLPATKAQAKEMLPIVDKPTIQYIVEEAVASGIEEIIIIIGRGKRSIEDHFDKSYELEDALLKKEKLDVLKEVQQISSLATIYYVRQKEPKGLGHAILCAQSFIGNEPFAVLLGDDIVMSETPCLKQIIDVFEYCNSSIVAVQSVPEKDISKYGIIKPKGTMIQPNLFSVACLVEKPKKEMAPSRYAIMGRYVLRPEIFKILTKLSVDQANNELQLTDAINELNKEQAVLAYNFEGNRYDIGDKVGFIKATIDFALHRDDIRNEVLAYLKDINAQDKFQITNEKFE
>NC_018687.1|WP_000703245.1|67023_68334_-|UDP-glucose/GDP-mannose-dehydrogenase-family-protein
MKISILGTGYVGLSTGVCLSEIGHSVICIDTDEQKIKSLNQGISPIYEPGLETLLTQNAAAGRLLFTTSHQEALNGAEIIIIAVGTPQMEDGRANLSYLEQAAKDIAVNLVKNAVIVIKSTVPVGTNEIIKKIMEDICNENVTLEIVSNPEFLRQGSAIMDTLKPDRIIIGSENEEVAKKIQEMYLPLNAPFLLTSIKSAEMIKYASNAYLATKISFINEIANLCEVIGSDVKDVVKGMGKDKRIGEAFLQPGIGYGGSCFPKDVKALLHTAKLHGIPFSLLKETVSINESQQELLVTKAINRLKDLKGKKITMLGLAFKPETDDMREAPSIKIAHSLVKLGAEVVAYDPAAIDNAKNILGDTIKFATSVFEATVHADAIFIVTEWNEFRCLELKELIKIMRQPIVFDGRNCFEEKQIRACDKIEYYPIGRPAIFI
>NC_018687.1|WP_148283634.1|64145_65585_-|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein
MDRSGFNVNQSVQYTNRDWMNYIPDSRRVSELSIPGTHDSMALYGPGEPIPIPIGDDATITQTMNLDIQLNSGIRYIDIRCRHYYDSLQIHHGPVYQHASFNDVLVSMKSFLTHNPREIILMRVKEEIEKLTPPVGNTRSFGETFKSYLRGNEQYFWDFLKSQNPYNPTLGEARGKIILLQDFEANTFLGIPWYSLRPTIQDEFELGGRDQIYAKWEKVREHFFNAMQNTGQIYLNHLSATGKPSNLWDPVPWFVASGYGGPQNTNLPRQLSGPSSQWPDNPRSPTSGFVYYGGTNVLSTRRIRERTFTHTGIVIADFPGKGLIDGTIALNFPGTLSGDFQIVTALNNSSVVDLNVGSKNVTLWENNKENHQRWNFTYNRSENAYVIHSVHNPELALAWDTSSPNRNVFATSIDSLRQNEYYWILEQIGNYIYIFKNKKDINMVLTVTGGEIQPGTNLQVYPRTVGNAQPAQTFVLKFI
>NC_018687.1|WP_000254349.1|59153_59966_+|hypothetical-protein
MVSMMVRIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIA
>NC_018687.1|WP_000254348.1|58193_59150_+|hypothetical-protein
MVSMMVRIVIVRIAGIMVNMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIAGIMVSMMVGIVIVRIA
>NC_018687.1|WP_000197242.1|56473_56740_-|hypothetical-protein
MTRKRFFDLCEGDRIKVYSAGRFEGEGIFIRFTEEKCEDFIYWIKRNGNDCYTSLDAINIEKIRYGYSYRDEQHHHHGDHKGEHRYDD
>NC_018687.1|WP_000368918.1|55201_55756_+|hypothetical-protein
MDNKHQNHIQSESQDNPLATNFESNIQHSNVKEKNHRLPFSIVLNIPNGFQIQKEKNPKVMYDLNHLSMIKETCKKSIDVDNCGYVEVDLHALKIKGCLSFLLNLYIEPIHDGKFYEKNSKDGSIALSYKETLHVDHVVKYSVGQLPYYVIDDEHVQIRHLEIQVFDENCNIVKISGEFYFEYE
>NC_018687.1|WP_000197243.1|54002_54275_-|hypothetical-protein
MTRKRFFDLCEGDRIKVYSAGRFEGEGIFIRFTEEKCEDFIYWIKRNGNDCYTSLDVINIEKIRYGYSHHDEQHHHDEDRKGEYRHDDSC
>NC_018687.1|WP_000495154.1|74227_75880_-|hypothetical-protein
MFTSGAKNRLKIETTDHEIDQAAISIECMSDEQDLQEKMMLWDEVKLAKQLSQSRNLLYNGNFEDSSNGWKTSNNITIQLGNLIFKGKYLNMPGARDIYGTIFPTYVYQKIEESKLKSYTRYRVRGFVGSSKDLKLMVTRYGKEIDASMDVPNGLAYMQPNLSCGDYRCDSSSPSMMSQGYPTPYTDGYASDMYACPSNFGKKHVKCHDRHPFDFHIDTGELDINTNLGICILFKISNPDGYATLGNLEVIEEGPLTGEALAHVKQKEKKWNQQMEKKRSETQQVYDPAKQAVDALFTNAQGEELHYHITLDHIQNANQLVQSIPYVHHAWLPDAPGMNYDVYQGLNARIMQAYNLYDARNVITNGDFAQGLTGWHATGKAAVQQMDGASVLVLSNWSAGVSQNLHAQDHHGYVLRVIAKKEGPGKGYVTMMDCNGNLETLKFTSCEEGYMTKTVEVFPESDRVRIEIGETEGTFYIDSIELLCMQGYASNNNPQTGNMYEQSYNQNTSDVYHQGYTNNYNQDSSSMYNQNYTNNDDQHSGCTCNQEYNC
>NC_018687.1|WP_000806152.1|75993_78057_-|hypothetical-protein
MKPYQNENEYEILDTLPKYSNIVNVYSRYPLANNPQVPLQNTSYKDWLNMCQTITPLCTPIDIDSKLVATAIGILGAIFKAMPGPGSAVGLFLKTFSTIIPILWPNDNTPIWKEFTKQGLQLFRPELGRDAIEIIGNDVQSGFNALKDHMNDFETKFEIWDKDRTQTNATYLITAFGVVNGKIIDLKNQFLINPANQPAFLNLYAQTANIDLILYQRGAVYGDDWAKAINDSSISPFNSSQIFYDSLKAKIKEYTNYCAETYRNSLTILKNQPNIQWDIYNRYRREATLGALDLVALFPNYDICKYPISTKTELTRKVYMPSFYLQALQHSNIETLENQLTHPPSLFTWLNELNLYTIRENFNPALQVSSLSGLQAKYRYTQNSTILPNPPAQGITNGTPIPIIGLNNLFIYKLSMSQYRHPNDCVPIAGISDMTFYKSDYNGNASATQTYQAGRNSNNVIDTFMNGPQNASSSNNISINQTNHILSDIKMNYARSGGVYDFGYSFAWTHTSVDPDNLIVPNRITQIPAVKANYLSSPARVIAGPGHTGGDLVALLNGGTQAGKMQIQCKTGSFTGASRRYGIRMRYAANNAFTVSLSYTLQGGNTIGTTFITERTFSRPNNIIPTDLKYEEFKYKEYNQIITMTSPQNTIVTIAIQQLNPIPNDQLIIDRIEFYPVDQGVFACPVN
>NC_018687.1|WP_080595736.1|78224_78554_-|DDE-type-integrase/transposase/recombinase
MNQNQRRENVLYLAIVSEGNTIDFYWSSRQNTKAAKYFLKKSLASYHAAKPRVITVESDKPHPVTIMELKNAKRIHSMPLRVKKYLNNIIEQDHRFIKKRSQNMLGLTT
>NC_018687.1|WP_000667332.1|78994_80155_-|site-specific-integrase
MKFELHTIHSDTSLDNIEKQKQNFTNIIALWNHDYINEAELKKENNEREDSYTYEGFSDEEILYYYLNRQTHFDQEKRIKDASRTLYARDLSQFYFFIKQSTEFLQQDVKDYVVGQVWRNLRKRHIRNYQKWLSQEAISYQSKVKYKTSTISRKLGVIRSYLKWLYEIQYIQEPLHVEILSTTVNKHHKPKRELSYEEVKQLLHYYKDNEINYALLSVLATTGLRVAEVAHAKWEDLEYDAIRGRYYLIVDTKGDNERIVSINKEIFNRIVAFRIRRRLPVDIGNKNGETIFQTKNHTAYKENYLSQYISKIIKDTKLPFTENIRITPHFFRHFYVQYLYDYKGLAPHVIAAAVGHKNDRTTKDNYLKQRLTKDNDAGNLITEDEF
>NC_018687.1|WP_000360259.1|80510_81494_+|hypothetical-protein
MDKNQQIIMNTTEVKEYLGVSHFVVNNLMKKGKLVPINKDTWRLDGSFLFESEDVKVIKKERETEGLTLYQASKKYNVSTYQLEKWLEDGELTATIHEHRNREMKFIKEEELRQISHRFDQVNALYTYSQKYNTVLYHRYIKGNTIARVISIPKRGDIMLIDEFGSEFTLKEAEKLGFIPAYDLSDKPRSHHRRFVRFRIPKSDQLRSSSFQLIDLILHYVSPRNLKVLEEEGFWYFDIRQSLIELPMGMQLEWIESLTPYLIEGKLVKRVNNSVYLDSSSVTRPVTMSSKEYQSINNIVGKTNSTIEEFIASAIREKIHNYQGSHN
>NC_018687.1|WP_148283635.1|82899_84312_+|phosphatidylinositol-specific-phospholipase-C-domain-containing-protein
MDRSGFNVNRTVNYTNRHWMGRIPDSRRISELSIPGTHGSMALHGGVAGTIGDIAINQTMNLETQLNSGIRYIDIRCRHYHNNFAIHHGRIYQHAFFGSHVLEPVISFLRRNPSETILMRIKEEYNPTGNTRTFSETFESFWTPNQRYFWTPTGSNPTLGEVRGRIIVLQDFPSWHRIFGIHWGQLNIQDRWNVAGDLDIYNKWIAVRNHFSIAMNNRTRISVNHLSGTGGSGSPRPWFLACGYMQRSNNAPLARLGSPIFPFPLDQFPDFPRSSATSGPVFFGGMNVLATRRIRERRFNHTGIVAADFPGIGLIEGTIALNFPGIIAGNHQIVTALNNSSVLDLNRGDQVTLWSNNQGNHQRWTFEYIFELQAYRIASVSNPNLVLTVDTPVRAASRVYASPNYGQRGQFWIMERGIWGYKLRSFGDPNLMLIVAGPTSADGANLVVYREHGGGNELVNRSQEFTFRPI
>NC_018687.1|WP_014990534.1|86091_87615_-|hypothetical-protein
MFTSGAKNMLKIETTDHEIDETAISIKTMLEEEHSQEKMMLWDEVKHAKYLSQSRNLLQNGDFEDLFNGWTTSNNMSIQNDNSTFKGQYLNMSGARDIDGTLFPTYIYQKIDESKLKPYTRYQIRGFVGSSKELKLMVIRYGKEIDTIMNVPNDIPHVSSMSSCNELYNSGQSLYQNKNVGYYNPMPEYTSNTYQHIPDQKQVICRDSHQFKFHIDTGEVDYNTNLGMLILFKISSPDGYATLDNLEGIEEGPLTDEALTHVKQKEKKWNQQMEKKRMETQQVYDPAKQAVDALFIHAQGEELQYNTTLDHIKNADQLAQSIPYVHHAWLPDVPGMNYDLYTDLNARIMHARYLYDARNVITNGNFTQGLQGWHATGHVDVQQMDGASVLVLSNWSTGVSQNLHAQDHHRYMLRVIAKKEGPGKGYVTMMDCNGKQETLTFTSCEEGYMTKTVKVFPESDRVRIEIGETEGSFYIESIELICMNGYTSNNNQNMSNMYDQSYDSNYS
>NC_018687.1|WP_000730235.1|91273_92200_-|ETX/MTX2-family-pore-forming-toxin
MKKKRMLLKWVCGLTIGIGSLTGGSLNTFADEVSDSLADVGFLYGDYLYKTKQHPQGTLPITYPMREINNYQIIDKSISQVGSTEYEEGQTLYVDDDVFDNKTDTDQTFKTIQFEKEFSETATSSTTHSVGTSLEESVKFDFFVGEGSAKFTVNYNFSKTGSLSTSNKIKYTLPSQSINVPANKKYEVICVLETKKAKANVQFNVDVLGNAKYVYSNNSPYTPKYENGATMVKTLNEKNPTPSVSWLGKEWEKWEYHDGKARYKNGSGTVSAEYGTRMVLVINDITNNKTRGSKEIARIPVTPIQKQM
>NC_018687.1|WP_001055929.1|92634_94068_-|IS4-family-transposase
MNMHQKQELSLFAEELYRYMSPATLNQLAIKAGGMKRKRKCHGHHFLSLCVWLNQQIATTSLTQLCSQLETSTGILLSPEGLNRRFNSDSVAFFRTVFTTLLQAKIGGVSKISHSLSSYFERILVLDSTTFQVPDRFATTYPGAGGCSHTAGVKIQLEYDLLSGKFSDVEIEPGKRSDQAYSATRTGMAQKNELYIRDLGYFRLQDFKSIQDKQGYYLSRLKLPTKIYRKEFETVVFKTKPAQLKPVYIQIHLEDIMKQLQPGQVYELHDVYVGSKDKLPTRIVVYRCTEEQKQKRLRDRAIREKKKGITYTERTKLLQGITVYMTNIPTEWVPKEKIYDLYSLRWQIELLFKIWKSWFQIHRCKSIKQERLECHLYGQLISILLCSSTMFKMRELLLRKKQKELSEYKAMYIIKDYFLLFYQALHKNTQELSKVLLRLFNLLQHNGRKSHRYEKKTVFDILGVVYEYTTSTHQVAQ
>NC_018687.1|WP_001243455.1|95832_96876_-|Fic-family-protein
MRNFFEDKYLDIELQRELIKLISEISEYKGKISAYQERNPDIFNNLEKTIPLHYIKNFNRVFLGIKVPNKRLKELILNGMLPKTTEEDAIFCYYQTLSLVQKKFYDLPTNPETIQELHFQLIHYITSDSAIWREKEFIVPVVPEYGMHSSSYRPLSRKLIPKSVEQLCEQYNILEANKELHSLILIARFMLNFYCILPFNQGNRRLAFILMQFLLMKNEYTFIKYICLDKYITKHESKYYESIFKSSVNWYCSGHNISFWLKIFLTIILDAYRDLHLIVQGSTCRYTKIERIKNYILKQKKPFTKEDIRGVYPDIAESTISKALASFQSLGHIKLVSRGRSAQWKRI

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018687_1	1.1\|25340\|60\|NC_018687\|CRISPRCasFinder	25340-25399	60	NC_018687	Bacillus thuringiensis MC28 plasmid pMC189, complete sequence	25340-25399	0	1.0
NC_018687_2	2.1\|73067\|47\|NC_018687\|CRISPRCasFinder	73067-73113	47	NC_018687	Bacillus thuringiensis MC28 plasmid pMC189, complete sequence	73067-73113	0	1.0
NC_018687_1	1.1\|25340\|60\|NC_018687\|CRISPRCasFinder	25340-25399	60	NZ_CP043834	Bacillus sp. BS98 plasmid unnamed4	11976-12035	5	0.917
NC_018687_1	1.1\|25340\|60\|NC_018687\|CRISPRCasFinder	25340-25399	60	NZ_CP043834	Bacillus sp. BS98 plasmid unnamed4	12062-12121	5	0.917
NC_018687_1	1.1\|25340\|60\|NC_018687\|CRISPRCasFinder	25340-25399	60	NZ_CP020436	Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence	25314-25373	5	0.917
NC_018687_1	1.1\|25340\|60\|NC_018687\|CRISPRCasFinder	25340-25399	60	NZ_CP020436	Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence	25400-25459	5	0.917
NC_018687_2	2.1\|73067\|47\|NC_018687\|CRISPRCasFinder	73067-73113	47	NC_018687	Bacillus thuringiensis MC28 plasmid pMC189, complete sequence	82817-82863	7	0.851
NC_018687_1	1.1\|25340\|60\|NC_018687\|CRISPRCasFinder	25340-25399	60	NZ_CP043834	Bacillus sp. BS98 plasmid unnamed4	12018-12077	9	0.85
NC_018687_1	1.1\|25340\|60\|NC_018687\|CRISPRCasFinder	25340-25399	60	NZ_CP020436	Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence	25356-25415	9	0.85
NC_018687_1	1.1\|25340\|60\|NC_018687\|CRISPRCasFinder	25340-25399	60	NC_018687	Bacillus thuringiensis MC28 plasmid pMC189, complete sequence	25296-25355	13	0.783

1. spacer 1.1|25340|60|NC_018687|CRISPRCasFinder matches to NC_018687 (Bacillus thuringiensis MC28 plasmid pMC189, complete sequence) position: , mismatch: 0, identity: 1.0

cttttgttatagatagataaccaaatttgttatctttagaaccattcttgttatagatag	CRISPR spacer
cttttgttatagatagataaccaaatttgttatctttagaaccattcttgttatagatag	Protospacer
************************************************************

2. spacer 2.1|73067|47|NC_018687|CRISPRCasFinder matches to NC_018687 (Bacillus thuringiensis MC28 plasmid pMC189, complete sequence) position: , mismatch: 0, identity: 1.0

cgtagttggaacaataacgtcccttgtttgatgatgtgatatccttg	CRISPR spacer
cgtagttggaacaataacgtcccttgtttgatgatgtgatatccttg	Protospacer
***********************************************

3. spacer 1.1|25340|60|NC_018687|CRISPRCasFinder matches to NZ_CP043834 (Bacillus sp. BS98 plasmid unnamed4) position: , mismatch: 5, identity: 0.917

cttttgttatagatagataaccaaatttgttatctttagaaccattcttgttatagatag	CRISPR spacer
tttttgttatagatagataaccaaatttgttatctttaaaaccatttttgttatagatga	Protospacer
.*************************************.*******.***********..

4. spacer 1.1|25340|60|NC_018687|CRISPRCasFinder matches to NZ_CP043834 (Bacillus sp. BS98 plasmid unnamed4) position: , mismatch: 5, identity: 0.917

cttttgttatagatagataaccaaatttgttatctttagaaccattcttgttatagatag	CRISPR spacer
tttttgttatagatagataaccaaatttgttatctttaaaaccatttttgttatagatga	Protospacer
.*************************************.*******.***********..

5. spacer 1.1|25340|60|NC_018687|CRISPRCasFinder matches to NZ_CP020436 (Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence) position: , mismatch: 5, identity: 0.917

cttttgttatagatagataaccaaatttgttatctttagaaccattcttgttatagatag	CRISPR spacer
tttttgttatagatagataaccaaatttgttatctttaaaaccatttttgttatagatga	Protospacer
.*************************************.*******.***********..

6. spacer 1.1|25340|60|NC_018687|CRISPRCasFinder matches to NZ_CP020436 (Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence) position: , mismatch: 5, identity: 0.917

cttttgttatagatagataaccaaatttgttatctttagaaccattcttgttatagatag	CRISPR spacer
tttttgttatagatagataaccaaatttgttatctttaaaaccatttttgttatagatga	Protospacer
.*************************************.*******.***********..

7. spacer 2.1|73067|47|NC_018687|CRISPRCasFinder matches to NC_018687 (Bacillus thuringiensis MC28 plasmid pMC189, complete sequence) position: , mismatch: 7, identity: 0.851

cgtagttggaacaataacgtcccttgtttgatgat-gtgatatccttg	CRISPR spacer
cgtagttggaacaataacgtcccttgtttgattatcacgatttccca-	Protospacer
******************************** ** ..*** ***.

8. spacer 1.1|25340|60|NC_018687|CRISPRCasFinder matches to NZ_CP043834 (Bacillus sp. BS98 plasmid unnamed4) position: , mismatch: 9, identity: 0.85

--cttttgttatagatagataaccaaatttgttatctttagaaccattcttgttatagat	CRISPR spacer
catttttgttatagatga--aaccaaatttgttatctttaaaaccatttttgttatagat	Protospacer
  .*************..  ********************.*******.***********

9. spacer 1.1|25340|60|NC_018687|CRISPRCasFinder matches to NZ_CP020436 (Bacillus sp. FDAARGOS_235 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.85

--cttttgttatagatagataaccaaatttgttatctttagaaccattcttgttatagat	CRISPR spacer
catttttgttatagatga--aaccaaatttgttatctttaaaaccatttttgttatagat	Protospacer
  .*************..  ********************.*******.***********

10. spacer 1.1|25340|60|NC_018687|CRISPRCasFinder matches to NC_018687 (Bacillus thuringiensis MC28 plasmid pMC189, complete sequence) position: , mismatch: 13, identity: 0.783

cttttgttatagataga---taaccaaatttgttatctttagaaccattcttgttataga	CRISPR spacer
---taagaatatatagaatgtaaccaaatttgttatctttagaaccacttttgttataga	Protospacer
   * .  *** *****   ***************************.*.**********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

78224 : 163995

Streptococcus_phage(25.0%)

integrase,tRNA,transposase

attL 73657:73676|attR 120779:120798

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
73657:73676	attL	NA	NA	NA	NA
WP_080595736.1\|78224_78554_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A1X9I6E7	Streptococcus_phage	3.2e-06	33.3
WP_000667332.1\|78994_80155_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_000360259.1\|80510_81494_+	hypothetical protein	NA	NA	NA	NA
WP_148283635.1\|82899_84312_+	phosphatidylinositol-specific phospholipase C domain-containing protein	NA	NA	NA	NA
WP_014990534.1\|86091_87615_-	hypothetical protein	NA	NA	NA	NA
WP_000730235.1\|91273_92200_-	ETX/MTX2 family pore-forming toxin	NA	NA	NA	NA
WP_001055929.1\|92634_94068_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_001243455.1\|95832_96876_-	Fic family protein	NA	NA	NA	NA
WP_000058822.1\|97358_98846_+	spore germination protein	NA	NA	NA	NA
WP_000527478.1\|98861_99962_+	endospore germination permease	NA	NA	NA	NA
WP_000288490.1\|101535_103188_-	hypothetical protein	NA	NA	NA	NA
WP_014990538.1\|103252_105262_-	pesticidal crystal protein	NA	NA	NA	NA
WP_000371897.1\|107788_108409_-	DUF3967 domain-containing protein	NA	NA	NA	NA
WP_000124664.1\|109047_109422_-	hypothetical protein	NA	NA	NA	NA
WP_001018641.1\|109423_110245_-	ParA family protein	F0PIG8	Enterococcus_phage	3.3e-52	44.6
WP_000473546.1\|111903_112173_+	hypothetical protein	NA	NA	NA	NA
WP_080595738.1\|112277_112379_-	YjcZ family sporulation protein	NA	NA	NA	NA
WP_000475291.1\|112656_113082_+	DUF4879 domain-containing protein	NA	NA	NA	NA
WP_000406883.1\|113186_113573_-	hypothetical protein	NA	NA	NA	NA
WP_001190697.1\|113632_115429_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	9.0e-34	26.6
WP_087991598.1\|117247_117394_+	hypothetical protein	NA	NA	NA	NA
WP_000410927.1\|118084_119434_+	YncE family protein	NA	NA	NA	NA
WP_000410923.1\|119622_120699_+	beta-propeller fold lactonase family protein	NA	NA	NA	NA
WP_000448254.1\|123135_123357_-	RNA chaperone Hfq	NA	NA	NA	NA
120779:120798	attR	NA	NA	NA	NA
WP_001202887.1\|123378_123660_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	9.1e-10	55.7
WP_000620809.1\|123859_124759_-	EamA family transporter	NA	NA	NA	NA
WP_000762456.1\|125174_126359_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000943139.1\|126391_127429_-	cysteine synthase family protein	A0A1W6JHY1	Lactococcus_phage	4.1e-39	35.4
WP_000251826.1\|127736_128444_-\|tRNA	alanyl-tRNA editing protein	NA	NA	NA	NA
WP_000637312.1\|128491_129391_-	kinase	NA	NA	NA	NA
WP_000454883.1\|129516_130959_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_181004266.1\|132145_132466_-	arylamine N-acetyltransferase	NA	NA	NA	NA
WP_001201432.1\|132909_133323_-	hypothetical protein	NA	NA	NA	NA
WP_000494383.1\|134314_134500_-	hypothetical protein	NA	NA	NA	NA
WP_014990559.1\|136875_138543_+	collagen-like protein	NA	NA	NA	NA
WP_000104995.1\|138924_139803_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_000836979.1\|142375_144502_-	phosphatidylinositol-specific phospholipase C domain-containing protein	NA	NA	NA	NA
WP_000804096.1\|144936_145164_-	hypothetical protein	NA	NA	NA	NA
WP_001055905.1\|145987_147421_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_001196891.1\|148236_149103_+	hypothetical protein	NA	NA	NA	NA
WP_001064653.1\|149178_150228_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_103592562.1\|151103_151571_+	HAD-IIIC family phosphatase	NA	NA	NA	NA
WP_001123487.1\|151604_151898_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000899478.1\|152014_152587_-	hypothetical protein	NA	NA	NA	NA
WP_000133497.1\|153117_153657_+	hypothetical protein	NA	NA	NA	NA
WP_000974221.1\|153753_154116_-	hypothetical protein	NA	NA	NA	NA
WP_043324653.1\|154633_154933_+	hypothetical protein	NA	NA	NA	NA
WP_000533915.1\|154963_155362_+	hypothetical protein	NA	NA	NA	NA
WP_043324655.1\|155606_155858_-	hypothetical protein	NA	NA	NA	NA
WP_001199494.1\|156173_156815_+	recombinase family protein	M9Q1K0	Clostridium_phage	1.8e-21	36.5
WP_000837527.1\|157372_158374_-	sphingomyelin phosphodiesterase	A0A1P8L6H7	Staphylococcus_phage	6.0e-88	57.9
WP_000823322.1\|158626_159607_-	hypothetical protein	NA	NA	NA	NA
WP_000377015.1\|160501_161902_-	phosphatidylinositol-specific phospholipase C	NA	NA	NA	NA
WP_000730172.1\|162299_162872_-	hypothetical protein	NA	NA	NA	NA
WP_014990573.1\|163311_163995_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	4.0e-67	58.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

7. NC_018686

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_018686_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018686_1

16801-17174

Orphan

Consensus_repeat	Method
GCAGGAGCAGCAACAGTACAACGTGATGTAAATGTACAAAACAATGTAAGAGGAAA	PILER-CR

4 spacers

The CRISPR arrays of NC_018686_1

>merge|NC_018686|1|16801-17174|PILER-CR
GCAGGTGTAGCGACAGTACAACGTGATGTGAATGTGCAAAATAATGTAAGAGGAAATGAAGCGGTAGAACAAACGGCAGGAGCAGCAACAGTACAACGTGATGTAAATGTACAAAACAATGTAAGAGGAAATGAAGCGGTAGAACAAACTGCAAGGGCAGGAGCAGCAACAGTACAACGTGATGTAAATGTACAAAATAATGTAAGAGGAAATGAAGCGGTAGAACAAACTGCAAGGGCAGGAGCAGCAACAGTACAACGTGATGTAAATGTACAAAACAATGTAAGAGGAAATGAAGCGGTAGAACAAACTGCAAGGGCAGGAGCAGCAACAGTACAACGTGATGTAAATGTACAAAACAATGTAAGAGGAAA

>NC_018686|1|1|16801-17174|PILER-CR
GCAGGTGTAGCGACAGTACAACGTGATGTGAATGTGCAAAATAATGTAAGAGGAAA	TGAAGCGGTAGAACAAACG
GCAGGAGCAGCAACAGTACAACGTGATGTAAATGTACAAAACAATGTAAGAGGAAA	TGAAGCGGTAGAACAAACTGCAAGG
GCAGGAGCAGCAACAGTACAACGTGATGTAAATGTACAAAATAATGTAAGAGGAAA	TGAAGCGGTAGAACAAACTGCAAGG
GCAGGAGCAGCAACAGTACAACGTGATGTAAATGTACAAAACAATGTAAGAGGAAA	TGAAGCGGTAGAACAAACTGCAAGG
GCAGGAGCAGCAACAGTACAACGTGATGTAAATGTACAAAACAATGTAAGAGGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018686.1\|WP_000239771.1\|20129_22067_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|223510
NC_018686.1\|WP_001067157.1\|18079_18289_+\|hypothetical-protein	unknown	unknown	unknown
NC_018686.1\|WP_000276031.1\|9583_11509_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224117
NC_018686.1\|WP_000367412.1\|19066_19381_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375135
NC_018686.1\|WP_001067103.1\|25843_26452_+\|hypothetical-protein	unknown	unknown	unknown
NC_018686.1\|WP_000994091.1\|23143_24949_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_018686.1\|WP_001052931.1\|9199_9499_+\|TrbC/VirB2-family-protein	unknown	unknown	gnl\|CDD\|368210
NC_018686.1\|WP_000657690.1\|18257_19034_+\|hypothetical-protein	unknown	unknown	unknown
NC_018686.1\|WP_000883996.1\|8384_8747_+\|hypothetical-protein	unknown	unknown	unknown
NC_018686.1\|WP_000666485.1\|4981_5365_+\|hypothetical-protein	unknown	unknown	unknown
NC_018686.1\|WP_000173523.1\|11535_14163_+\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	unknown	unknown	gnl\|CDD\|378923
NC_018686.1\|WP_043324456.1\|19444_20113_+\|hypothetical-protein	unknown	unknown	unknown
NC_018686.1\|WP_000235841.1\|8930_9182_+\|hypothetical-protein	unknown	unknown	unknown
NC_018686.1\|WP_001266824.1\|7594_8344_+\|hypothetical-protein	unknown	unknown	unknown
NC_018686.1\|WP_000892404.1\|8765_8912_+\|hypothetical-protein	unknown	unknown	unknown
NC_018686.1\|WP_001192105.1\|22068_22491_+\|lysozyme-family-protein	unknown	unknown	gnl\|CDD\|372680
NC_018686.1\|WP_000888325.1\|5381_6731_+\|Flp-pilus-assembly-complex-ATPase-component-TadA	unknown	unknown	gnl\|CDD\|227297
NC_018686.1\|WP_000926960.1\|26540_26816_+\|DUF5513-family-protein	unknown	unknown	gnl\|CDD\|340347
NC_018686.1\|WP_000704107.1\|6764_7598_+\|hypothetical-protein	unknown	unknown	unknown
NC_018686.1\|WP_014990426.1\|17804_18083_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_018686.1\|WP_000239771.1\|20129_22067_+\|ATP-binding-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	4.66573e-08
NC_018686.1\|WP_000173523.1\|11535_14163_+\|type-IV-secretory-system-conjugative-DNA-transfer-family-protein	gnl\|CDD\|378923	pfam12696, TraG-D_C, TraM recognition site of TraD and TraG. This family includes both TraG and TraD as well as VirD4 proteins. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. This domain interacts with the relaxosome component TraM via the latter's tetramerisation domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore.	8.03237e-26
NC_018686.1\|WP_000276031.1\|9583_11509_+\|hypothetical-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	4.94305e-05
NC_018686.1\|WP_000367412.1\|19066_19381_+\|hypothetical-protein	gnl\|CDD\|375135	pfam17332, pXO2-11, Uncharacterized protein pXO2-11. This is a protein of unknown function found in Firmicutes and predicted to contain 2 trans-membrane regions.	0.00445884
NC_018686.1\|WP_000994091.1\|23143_24949_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.28575e-109
NC_018686.1\|WP_001052931.1\|9199_9499_+\|TrbC/VirB2-family-protein	gnl\|CDD\|368210	pfam04956, TrbC, TrbC/VIRB2 family. Conjugal transfer protein, TrbC has been identified as a subunit of the pilus precursor in bacteria. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains several VIRB2 type IV secretion proteins. The virB2 gene encodes a putative type IV secretion system and is known to be a pathogenicity factor in Bartonella species.	3.2359e-07
NC_018686.1\|WP_001192105.1\|22068_22491_+\|lysozyme-family-protein	gnl\|CDD\|372680	pfam13702, Lysozyme_like, Lysozyme-like.	2.64815e-18
NC_018686.1\|WP_000888325.1\|5381_6731_+\|Flp-pilus-assembly-complex-ATPase-component-TadA	gnl\|CDD\|227297	COG4962, CpaF, Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion].	7.64612e-30
NC_018686.1\|WP_000926960.1\|26540_26816_+\|DUF5513-family-protein	gnl\|CDD\|340347	pfam17632, DUF5513, Family of unknown function (DUF5513). This is a family of unknown function found in Bacillus.	7.41824e-51

>NC_018686.1|WP_000173523.1|11535_14163_+|type-IV-secretory-system-conjugative-DNA-transfer-family-protein
MTLLKFKRNKYLHHNYNIDGEDLPQEKNRINKKALAISSLAVLFPLGGLNFVAGTYYAIVNELSKTVEKPTIFDVFGTDWEQGISIKNVFLPVLPTNMYLFGLLASTVMGFLVYSKVNYRSDENVAYGQKGDSRFTTIEEIQEQYREIPEKTETFEGYGGVPVSHYKNKYYVDTDTVNTAILGVSRSGKGETIVVPMIDNLSRAKNQSSMVVNDPKGELYSASKETLEKRGYDVQVLNISEPLQGMSYNPLQLVIDAWVNGDDQEAAKRANTLTFSLYNNPNAGDNAFFNTSAQNAINGIILAIVDYCVKNNCIEKITMHNVSQMLNELGTFYYKENPDDFTEKSALDEYFKSLPQGNVAKMQYGSTSFAGEKAKGSILATANQGLQTFADKMIAKMTSKSSLDLKQVGFPKNLFFQLDERFLNKRVTVSFHKNNQEKTEILSYEIKVKALGMCNMNFDESLEDGDLLLIRYQDAENPKKKYRLFYSLQFEKLLDEKGQVVYQKKEGCGNKPEYQRQVTLILKANTFPLQPKAKLSYSNKPTAVFMIVPDYDKSNHALASIFVKQLYTELSMNCNDTKGKKCYRRVHYLLDEFGNMPPIDDMGGVLTVCAGRNMLFNLVLQSYSQIEKLYDKQAKEIKQNCQNHLYIMSTDPETIEEISKRAGHETIIGKSSNESYLDTDNKVTKSADQQRIISPDRLSQFLEGETLVIRALHRQDLNRKKVRPYPIFNTQGMTMPFRWQFLSSLFDTSNDLNDIDIPSLHTGLDLTELYLNFLDFILNPVAKKEYIKKQQANPIVKKEQTDINEEIKSLIGLVKEKRNRNDTEDIQKRLVQMLLTYATKSMLPKTEEVKFLIEHSSDMEIKRHLEDLLGMLESN
>NC_018686.1|WP_000276031.1|9583_11509_+|hypothetical-protein
MYIVEFLQKEQSKAFKKFLRKNKAGNGKQLGLKVAEELIQRYIEQNQQSDQILLLLQDVENEKAYEFELPVQVGSKFSLLTAISNDLEKGTDFNLGMEIKQGIYESYRAEEGGAVIEHEEGAPKKKKGGLFAKLFGKNEEVPHGDNEVKKEFAGVEGNPFEEMPMHELKSKGTHHFEDEDIQGLQEHAAALNQKEDDDPFAIEEEHGELPTGVNLEKAVEELPFPTNEVDSVQSIEEELFNSDSDVQKINQEPVIEAQNQEVSFPDYEEYLNLSEVEKKQERYDSRFTIMHLLSRFGMSEEATTGLGKKKLQYAKNVLSGKDFLLIQDKYYQEINNLRDEIRLALENIYKEVMMRDYQKEAEERLQDIFEQGFQTRLAELNEFENKEMQEMHKKLSAFTEKQRLALESFKLQQEAELTAYQTELEERKNTLISACEEELKKENEIEKRKATLEKVYELKVEGKKELIDKKNEYLSDSIEMTEQIMNAANEQQEVRFSVLEDEIKQLIPEWKEEIQAEHDKEMKERQLKIEEEKNRIEVEALNLQQRKEEAKEVRSNDREQKLLNIIEDLKEKLLKAHANPEQQPLQQPVIMYPQPVQQPVYMYQQPVQQAPIQPQQPVMQQQTKTSTKKRRTFLARLMDSE
>NC_018686.1|WP_001052931.1|9199_9499_+|TrbC/VirB2-family-protein
MNLPKLNLLETAKSSLQTVVYNDFFDSVRSALTSWSGKLQGLGIAVIIFCVCIIAFMFMFGEGPSRTAKKWLMYIVVGGVLLWGAGTFASTVQGVTSGF
>NC_018686.1|WP_000235841.1|8930_9182_+|hypothetical-protein
MATSPRRNKVEKAPYQDAVTVILKKEGKTYESWSQEIVNSNCLSLLQGENPKWRNKMLEAASMEIIADSVVKQEEKRQNHSNN
>NC_018686.1|WP_000892404.1|8765_8912_+|hypothetical-protein
MLENNVFRLMVLMGGVMVLIAIITHCVDGIPEVEDVFQHFISHKNTKY
>NC_018686.1|WP_000883996.1|8384_8747_+|hypothetical-protein
MLDGSIMLIVKWFVGLMLIMMMVAVALFSIQLSDVNSYKQQVNYQIERHGGLTKEAAANLKDYSKKQYRGALSVKSDQLNKKVNFGDVVDYQVVANLKIILFDLPDVKMEFHGSAISQVR
>NC_018686.1|WP_001266824.1|7594_8344_+|hypothetical-protein
MRVVAAKSIKKNRYNRLFAEEDLYSMLEEMGNTQQMINKFQKKRLIQTLLLSFFGLLLGLFITSWCYLLALGLPFFFYRSKYTYVTKMYNAFKFERHLNFSKFTRLLIPYLKESGGSISLYQVFRKILNRMDNPVDKNSLAKLMSEMTDKPNDIQPFTDYALRSSGSDMSLNIMQTIYDFQQNSSDTNVINELGQMASAELQRAIDEIIAFKLRRFNFFPTKIVMSSFILVVGYAAAVLVLQLSAINFS
>NC_018686.1|WP_000704107.1|6764_7598_+|hypothetical-protein
MKISTFNAKTKKKKFVNAEEINAFKVAYGKPLNKKDYLRYAIIPGLVTGIFSFLLLYIWWLSLILGCIGALYGLKVLMPKIIKRAYERDSFRERNKFVNNMTSLLSNENKTLFTALDQASDRAEGELRGDLKILMANILGADQEQVLQAFKQTSNKYREDITFDQYLEQLETCVLEGRTNLETLKDIKTHHNETKEKKDDYERKKEGHLKDMKMLCGVIVVFVLAISFSFGFKTYLTAFAGHPIGWITSGIYMTLMFFFFKTFTTYLFDDSIMEVKT
>NC_018686.1|WP_000888325.1|5381_6731_+|Flp-pilus-assembly-complex-ATPase-component-TadA
MLEAIKNVSVKKKKENKFNDFSSVNFQKSLEAIRNDLKNSKAELVIDAMLKEEARQKIKDIIKEKYAAHFMDFPEDKLVEVYEYVVSEIVGTGVIERLINERPDITDISYNSSHLIVESSDYKEVHRDTDHQISEQYITRVIQKFAHAVGKEFAPKTPIFDGVYDSIRINAVHHQNTTGNSTMSLRIVRPRLALHEGNFETFAPTFMLEFFRILMETRNNIVISGETGTGKTEFLKLLFSYIRFEHKAIMIEDVPETHVKKLFPDKDVFSWLTGHGVTVTDLIEAALRNNPRWIMISELRGKEAYEMIQAVFSGHHIVTSLHSVDAETSPKRLVNMSKMGYQFDEKSLEEDILRYFNFGCHIKRLVVKTTKQGNVQINRVIRYLAKVVEYSPEGNRTVFEQKYKNGKFTYSTGSLSNQFYEKLAENDMNYTLPDFKDEVAVKKGLVISR
>NC_018686.1|WP_000666485.1|4981_5365_+|hypothetical-protein
MKEYPFILVIIVLGIFLVSIGGYYYRENFATDSVTQGVTETVRASVISNVDNSSRVQSGELFIVKSDFEKDFKKRIESNKLVKIGNDAKYEFKYLDNKNGSTKAIRAIIQDRDQTYQATYKVSIAAS
>NC_018686.1|WP_014990426.1|17804_18083_+|hypothetical-protein
MILGGLNVKVIDIANQRRIYFEMKQRESQASILIIIAGLFAAVAILVFQISFELVHLYHYIVIFSFLTYFSLHLYSKNKSSKNREKAKGILR
>NC_018686.1|WP_001067157.1|18079_18289_+|hypothetical-protein
MNNWIFAILMLGVAIVLSMIVTFLKQIFRVLRRKKKKDPKLVTVMNAEYVNQDFWGRNFYERVSNRNTK
>NC_018686.1|WP_000657690.1|18257_19034_+|hypothetical-protein
MKEFLIEILNNQFVMQIIFTTTLSFVVYMICFIAYNGGLWRDMQLDAKEHIFLELDPLLRIIVKPALLSWLIYDKPFIKQWFLWSLDHTLVKWIIGILFVLMVGVWILQIAMWVYCFVRETIYAIIRWKRKQRIAFTTQEEEIFDFCADKFPSYTEKYLANELTHSVEAKEIIYKSLLCLHILNPKGVRDYFGLSVYEYEIEYYPEEHPVKQYYAKFEKYPLFKKECMENDIKMFKTMNLFIKSTIREYKSCNKEGKN
>NC_018686.1|WP_000367412.1|19066_19381_+|hypothetical-protein
MDMMRNPKNTKQEIKLAFFYIMDGAIIALMLVLASYMPKVVPVGGFGRIMFYVLFGALGLFLCIKPHNSPTNRNIFVILDMLKMDNKNYHPIEVNTISSETKKK
>NC_018686.1|WP_043324456.1|19444_20113_+|hypothetical-protein
MRVATVESKKVNRKRQIESENSNGKQSFISTIFASFKNTDASIVNIAPYKRLEQKTGVLVDHRDNLQVYLKVKTTDLLSMNQDDLKRFMNQLTSLCRVYHEPFKVLSLTYSTETTEQQVYWKRMALRYQGKMSQDVSEKKEEHLWYQRYSLAIENLNRVLWVEKNLKELAFFIVVYGKSETELIKNVKDMKRYGGRQFNLQNMKAKEVEKLIFKLQNMNSEM
>NC_018686.1|WP_000239771.1|20129_22067_+|ATP-binding-protein
MVKLGKKDQQKYRTEGYDLDFISRMQPQGGIKFNEKYIAQGDCYVACLHVYSLAEDIPPLWLTALMNNKDTISSVDIATANKEEVVRDINRSITELKDRTTSERRSTDRDDAHWELQNLTDFARSITQQGEIVKLIKLRIFIYDPVLEQLEKRIGDIKKEIAGQNYKAQVYVFKQKEEWQTLFASYDDQMEYLGVKSGYPLPSKNIGFGIPFHHQDLKDPRGIYLGQTSTGGAFILDPFFSTSTRTSFSGFVFGKMGAGKSTLLKQLLEGLLAKDCFIRGFDKAKDYYTIVQQQGGKIIDLSGAKSNGIVETGRINPLEVFATIIDDDTGEVNEKGSFLQHLSKLTNNLRFLSVDISETAVKEFRNYLLEFYIEYGLIPRREDNKPLKITGLAPTDYPIMEEFLEYLNGVQLEKGSTAQRLRDLETLRVQVRDMVFVYGDIFNGHTTLRNFEDEKIVIFDIDGISKIDKPIFNCQLFTALTLIWSHALKNGRRMKYLREEKKYPVEDLTYFMVLLDECHNVINSENKFANKYILEFEREMRKFLAGIFFATQSPQEMLPPPGSNVDVSDMKAIFELTQYKIFLNMDNSVLENLKGVLGESLTESEFSILPELKRGEAIVQVSSTETFNVMFDPDEKQLERFKGGQ
>NC_018686.1|WP_001192105.1|22068_22491_+|lysozyme-family-protein
MQSTQEAQSSVVDKYKKVKKIKRLSSLIGGTSGVLVVGVTILLVIVLIGIFGGGNSKSTSTGGGISGTASVQNLPPEVMRWKEMVEKECAAQGVPELVPYVLAIIMVESNGISERLPDIMQSSGATRFSISTLVRNESVA
>NC_018686.1|WP_000994091.1|23143_24949_+|group-II-intron-reverse-transcriptase/maturase
MNARMRYWEYYNMQETFDKLYEDSRANKPFQGLYEMITAENNILLAYRTIKSNKGSKTAGIDSFAIDQYKSMDKAEFLNLVRNRLNQYKPKAVKRVFIPKPNGDKRPLGIPTMFDRLIQQMIKQILEPICEAKFYEHSYGFRPLRGARHAISRVMYLISRNTFHYAVEIDIKGFFDNVNHTLLLKQLWNMGIKDKRVLKLIYLILKAPIKGVGIPRKGTPQGGILSPLLSNVVLNDLDQWIARQWHHFQSDYDYTEPGNRSRALKRTKLKQGYIVRYADDFKIMAKDFRTAQKWFMATKLYLKERLKLDISPGKSRIINLRKNKSEFLGYSLYVVPKRNKWVCNSNISEKKKKQIESELRKRIKSIQRSTTRQNVQLYNAYVLGLRNYFRYATHVNIDMHELTFSVSLTFFNRLKSVGKYEVPINAPPVYKKFFKNNYRTFKVCGIYLFPLADIQTATIWNYTQSQTPYSKKGRNSAEHKELDRNVLVEITRLLTVNTISRSLEYSDNRISRYSMVMGKCEILKEFLTASEVHCHHYVPLGLGGTDDYSNLRIIRKDIHRLIHATDNRTIENYLKSLLLTDEQVKRINQYRRACNLEEIKY
>NC_018686.1|WP_001067103.1|25843_26452_+|hypothetical-protein
MNNVSKILGVVLILSLAYNGILSYSTKQEFDKKDKKYHTTVSEKEKQIGDLKVKLEQESKKVNEGAADENKKESNPTLDLQNKYREVANQFVHAYLDYSVQNKGERRNNLLKITDKKVVDVVAPNTDDLGDPNFKSHVNKAAIYVNSEGDISKICTSLLDVEYTIEGLENKKTTINSVVKITLEKQGEEIKVVEYNPYPVKR
>NC_018686.1|WP_000926960.1|26540_26816_+|DUF5513-family-protein
MLLSELKPNHDYVKEGRYLILSLRKKKGIRKDKFIEIPITWFDYNFGEKVEWLIVREYQSSVNGKEKYTNYKLENIHAQVSVVNVKGETTK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_018686_1	1.1\|16857\|19\|NC_018686\|PILER-CR	16857-16875	19	NC_018693.1	4506398-4506416	2	0.895
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686.1	17256-17280	0	1.0
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686.1	17418-17442	0	1.0
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686.1	17175-17199	1	0.96
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686.1	17256-17280	0	1.0
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686.1	17418-17442	0	1.0
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686.1	17175-17199	1	0.96
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686.1	17256-17280	0	1.0
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686.1	17418-17442	0	1.0
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686.1	17175-17199	1	0.96

1. spacer 1.1|16857|19|NC_018686|PILER-CR matches to position: 4506398-4506416, mismatch: 2, identity: 0.895

tgaagcggtagaacaaacg	CRISPR spacer
tgaagcggtaggagaaacg	Protospacer
***********.* *****

2. spacer 1.2|16932|25|NC_018686|PILER-CR matches to position: 17256-17280, mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

3. spacer 1.2|16932|25|NC_018686|PILER-CR matches to position: 17418-17442, mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

4. spacer 1.2|16932|25|NC_018686|PILER-CR matches to position: 17175-17199, mismatch: 1, identity: 0.96

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagaggtagaacaaactgcaagg	Protospacer
***** *******************

5. spacer 1.3|17013|25|NC_018686|PILER-CR matches to position: 17256-17280, mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

6. spacer 1.3|17013|25|NC_018686|PILER-CR matches to position: 17418-17442, mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

7. spacer 1.3|17013|25|NC_018686|PILER-CR matches to position: 17175-17199, mismatch: 1, identity: 0.96

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagaggtagaacaaactgcaagg	Protospacer
***** *******************

8. spacer 1.4|17094|25|NC_018686|PILER-CR matches to position: 17256-17280, mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

9. spacer 1.4|17094|25|NC_018686|PILER-CR matches to position: 17418-17442, mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

10. spacer 1.4|17094|25|NC_018686|PILER-CR matches to position: 17175-17199, mismatch: 1, identity: 0.96

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagaggtagaacaaactgcaagg	Protospacer
***** *******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018686_1	1.1\|16857\|19\|NC_018686\|PILER-CR	16857-16875	19	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	16857-16875	0	1.0
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	16932-16956	0	1.0
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17013-17037	0	1.0
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17094-17118	0	1.0
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17256-17280	0	1.0
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17418-17442	0	1.0
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	16932-16956	0	1.0
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17013-17037	0	1.0
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17094-17118	0	1.0
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17256-17280	0	1.0
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17418-17442	0	1.0
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	16932-16956	0	1.0
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17013-17037	0	1.0
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17094-17118	0	1.0
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17256-17280	0	1.0
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17418-17442	0	1.0
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17175-17199	1	0.96
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17337-17361	1	0.96
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17175-17199	1	0.96
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17337-17361	1	0.96
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17175-17199	1	0.96
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	17337-17361	1	0.96
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	67883-67907	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68045-68069	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68207-68231	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68369-68393	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68450-68474	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	69574-69598	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	69736-69760	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	69898-69922	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	70060-70084	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	70141-70165	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_MG710485	Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence	33559-33583	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_MG710485	Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence	33640-33664	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	18678-18702	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	18759-18783	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	18921-18945	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	19083-19107	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	19245-19269	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	67883-67907	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68045-68069	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68207-68231	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68369-68393	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68450-68474	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	69574-69598	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	69736-69760	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	69898-69922	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	70060-70084	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	70141-70165	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_MG710485	Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence	33559-33583	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_MG710485	Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence	33640-33664	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	18678-18702	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	18759-18783	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	18921-18945	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	19083-19107	2	0.92
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	19245-19269	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	67883-67907	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68045-68069	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68207-68231	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68369-68393	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP015154	Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence	68450-68474	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	69574-69598	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	69736-69760	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	69898-69922	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	70060-70084	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP013059	Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence	70141-70165	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_MG710485	Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence	33559-33583	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_MG710485	Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence	33640-33664	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	18678-18702	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	18759-18783	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	18921-18945	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	19083-19107	2	0.92
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP011351	Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence	19245-19269	2	0.92
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	16857-16881	3	0.88
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP031066	Bacillus sp. SH8-8 plasmid pl193, complete sequence	35823-35847	3	0.88
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP031063	Bacillus sp. AR4-2 plasmid pl192, complete sequence	35823-35847	3	0.88
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP018742	Bacillus cereus strain FORC_047 plasmid pFORC47_2, complete sequence	61050-61074	3	0.88
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	16857-16881	3	0.88
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP031066	Bacillus sp. SH8-8 plasmid pl193, complete sequence	35823-35847	3	0.88
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP031063	Bacillus sp. AR4-2 plasmid pl192, complete sequence	35823-35847	3	0.88
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP018742	Bacillus cereus strain FORC_047 plasmid pFORC47_2, complete sequence	61050-61074	3	0.88
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NC_018686	Bacillus thuringiensis MC28 plasmid pMC183, complete sequence	16857-16881	3	0.88
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP031066	Bacillus sp. SH8-8 plasmid pl193, complete sequence	35823-35847	3	0.88
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP031063	Bacillus sp. AR4-2 plasmid pl192, complete sequence	35823-35847	3	0.88
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP018742	Bacillus cereus strain FORC_047 plasmid pFORC47_2, complete sequence	61050-61074	3	0.88
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP031066	Bacillus sp. SH8-8 plasmid pl193, complete sequence	35580-35604	4	0.84
NC_018686_1	1.2\|16932\|25\|NC_018686\|PILER-CR	16932-16956	25	NZ_CP031063	Bacillus sp. AR4-2 plasmid pl192, complete sequence	35580-35604	4	0.84
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP031066	Bacillus sp. SH8-8 plasmid pl193, complete sequence	35580-35604	4	0.84
NC_018686_1	1.3\|17013\|25\|NC_018686\|PILER-CR	17013-17037	25	NZ_CP031063	Bacillus sp. AR4-2 plasmid pl192, complete sequence	35580-35604	4	0.84
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP031066	Bacillus sp. SH8-8 plasmid pl193, complete sequence	35580-35604	4	0.84
NC_018686_1	1.4\|17094\|25\|NC_018686\|PILER-CR	17094-17118	25	NZ_CP031063	Bacillus sp. AR4-2 plasmid pl192, complete sequence	35580-35604	4	0.84

1. spacer 1.1|16857|19|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaacg	CRISPR spacer
tgaagcggtagaacaaacg	Protospacer
*******************

2. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

3. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

4. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

5. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

6. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

7. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

8. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

9. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

10. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

11. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

12. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

13. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

14. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

15. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

16. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaagg	Protospacer
*************************

17. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 1, identity: 0.96

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagaggtagaacaaactgcaagg	Protospacer
***** *******************

18. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 1, identity: 0.96

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaacg	Protospacer
*********************** *

19. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 1, identity: 0.96

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagaggtagaacaaactgcaagg	Protospacer
***** *******************

20. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 1, identity: 0.96

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaacg	Protospacer
*********************** *

21. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 1, identity: 0.96

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagaggtagaacaaactgcaagg	Protospacer
***** *******************

22. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 1, identity: 0.96

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaactgcaacg	Protospacer
*********************** *

23. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

24. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

25. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

26. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

27. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

28. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

29. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

30. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

31. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

32. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

33. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_MG710485 (Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

34. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_MG710485 (Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

35. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

36. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

37. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

38. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

39. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

40. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

41. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

42. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

43. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

44. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

45. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

46. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

47. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

48. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

49. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

50. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_MG710485 (Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

51. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_MG710485 (Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

52. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

53. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

54. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

55. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

56. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

57. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

58. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

59. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

60. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

61. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP015154 (Bacillus thuringiensis strain Bc601 plasmid pBTBC4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

62. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

63. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

64. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

65. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

66. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP013059 (Bacillus thuringiensis strain YWC2-8 plasmid pYWC2-8-4, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

67. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_MG710485 (Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

68. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_MG710485 (Bacillus thuringiensis serovar israelensis strain Bti-UFT6.51 plasmid pBtiUFT6.51.1 complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

69. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

70. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

71. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

72. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

73. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP011351 (Bacillus thuringiensis strain YC-10 plasmid pYC3, complete sequence) position: , mismatch: 2, identity: 0.92

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagagcatactgcaagg	Protospacer
************.** *********

74. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaacggcagga	Protospacer
****************** ***.*.

75. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP031066 (Bacillus sp. SH8-8 plasmid pl193, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaaccgtaaga	Protospacer
******************.*.***.

76. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP031063 (Bacillus sp. AR4-2 plasmid pl192, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaaccgtaaga	Protospacer
******************.*.***.

77. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP018742 (Bacillus cereus strain FORC_047 plasmid pFORC47_2, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacatactgtaaga	Protospacer
*************** ****.***.

78. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaacggcagga	Protospacer
****************** ***.*.

79. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP031066 (Bacillus sp. SH8-8 plasmid pl193, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaaccgtaaga	Protospacer
******************.*.***.

80. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP031063 (Bacillus sp. AR4-2 plasmid pl192, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaaccgtaaga	Protospacer
******************.*.***.

81. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP018742 (Bacillus cereus strain FORC_047 plasmid pFORC47_2, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacatactgtaaga	Protospacer
*************** ****.***.

82. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NC_018686 (Bacillus thuringiensis MC28 plasmid pMC183, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaacggcagga	Protospacer
****************** ***.*.

83. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP031066 (Bacillus sp. SH8-8 plasmid pl193, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaaccgtaaga	Protospacer
******************.*.***.

84. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP031063 (Bacillus sp. AR4-2 plasmid pl192, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacaaaccgtaaga	Protospacer
******************.*.***.

85. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP018742 (Bacillus cereus strain FORC_047 plasmid pFORC47_2, complete sequence) position: , mismatch: 3, identity: 0.88

tgaagcggtagaacaaactgcaagg	CRISPR spacer
tgaagcggtagaacatactgtaaga	Protospacer
*************** ****.***.

86. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP031066 (Bacillus sp. SH8-8 plasmid pl193, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcggtagaacaaactgcaagg	CRISPR spacer
cgaagcggtagaacaaaccgtaaga	Protospacer
.*****************.*.***.

87. spacer 1.2|16932|25|NC_018686|PILER-CR matches to NZ_CP031063 (Bacillus sp. AR4-2 plasmid pl192, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcggtagaacaaactgcaagg	CRISPR spacer
cgaagcggtagaacaaaccgtaaga	Protospacer
.*****************.*.***.

88. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP031066 (Bacillus sp. SH8-8 plasmid pl193, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcggtagaacaaactgcaagg	CRISPR spacer
cgaagcggtagaacaaaccgtaaga	Protospacer
.*****************.*.***.

89. spacer 1.3|17013|25|NC_018686|PILER-CR matches to NZ_CP031063 (Bacillus sp. AR4-2 plasmid pl192, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcggtagaacaaactgcaagg	CRISPR spacer
cgaagcggtagaacaaaccgtaaga	Protospacer
.*****************.*.***.

90. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP031066 (Bacillus sp. SH8-8 plasmid pl193, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcggtagaacaaactgcaagg	CRISPR spacer
cgaagcggtagaacaaaccgtaaga	Protospacer
.*****************.*.***.

91. spacer 1.4|17094|25|NC_018686|PILER-CR matches to NZ_CP031063 (Bacillus sp. AR4-2 plasmid pl192, complete sequence) position: , mismatch: 4, identity: 0.84

tgaagcggtagaacaaactgcaagg	CRISPR spacer
cgaagcggtagaacaaaccgtaaga	Protospacer
.*****************.*.***.

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage