CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP007568	Aeromonas media WS plasmid pWSY, complete sequence	0 crisprs	NA	0	0	0	0
NZ_CP007567	Aeromonas media WS chromosome, complete genome	13 crisprs	csa3,c2c9_V-U4,cas14j,DEDDh,WYL,DinG,cas3	0	5	29	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NZ_CP007567_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_1

2713-2809

Orphan

Consensus_repeat	Method
GGAGGACATCGGCAAGGTGTTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_1

>merge|NZ_CP007567|1|2713-2809|CRISPRCasFinder
GGAGGACATCGGCAAGGTGTTCACTTACGAGCAGCCCAAGGGCTAGATGTAGGGCCGGCTCACCGGCTATGGTCGGAGGAGATCGGCAAGGTGTTCA

>NZ_CP007567|1|1|2713-2809|CRISPRCasFinder
GGAGGACATCGGCAAGGTGTTCA	CTTACGAGCAGCCCAAGGGCTAGATGTAGGGCCGGCTCACCGGCTATGGTC
GGAGGAGATCGGCAAGGTGTTCA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_005331314.1\|18082_18607_-\|ribosome-associated-protein	unknown	unknown	gnl\|CDD\|235377
NZ_CP007567.1\|WP_041204874.1\|4110_5175_-\|DUF3103-family-protein	unknown	unknown	gnl\|CDD\|371456
NZ_CP007567.1\|WP_005331315.1\|18718_20062_+\|metalloprotease-PmbA	unknown	unknown	gnl\|CDD\|182922
NZ_CP007567.1\|WP_041204875.1\|14931_18015_+\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|223815
NZ_CP007567.1\|WP_005327753.1\|6589_7159_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380339
NZ_CP007567.1\|WP_025328544.1\|14399_14717_+\|DUF496-family-protein	unknown	unknown	gnl\|CDD\|180070
NZ_CP007567.1\|WP_005327748.1\|2840_3359_-\|tyrosine-protein-phosphatase	unknown	unknown	gnl\|CDD\|350355
NZ_CP007567.1\|WP_025325515.1\|3519_3990_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP007567.1\|WP_005327752.1\|5322_6474_-\|benzoate/H(+)-symporter-BenE-family-transporter	unknown	unknown	gnl\|CDD\|281578
NZ_CP007567.1\|WP_041204871.1\|427_1666_-\|HD-GYP-domain-containing-protein	unknown	unknown	gnl\|CDD\|225116
NZ_CP007567.1\|WP_005327754.1\|7162_8359_-\|NnrS-family-protein	unknown	unknown	gnl\|CDD\|377571

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_005331314.1\|18082_18607_-\|ribosome-associated-protein	gnl\|CDD\|235377	PRK05255, PRK05255, ribosome-associated protein.	4.42417e-66
NZ_CP007567.1\|WP_041204874.1\|4110_5175_-\|DUF3103-family-protein	gnl\|CDD\|371456	pfam11301, DUF3103, Protein of unknown function (DUF3103). This family of proteins with unknown function appear to be restricted to Proteobacteria.	3.63428e-167
NZ_CP007567.1\|WP_005331315.1\|18718_20062_+\|metalloprotease-PmbA	gnl\|CDD\|182922	PRK11040, PRK11040, peptidase PmbA; Provisional.	0
NZ_CP007567.1\|WP_041204875.1\|14931_18015_+\|penicillin-binding-protein	gnl\|CDD\|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	2.35995e-77
NZ_CP007567.1\|WP_005327753.1\|6589_7159_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	2.47425e-19
NZ_CP007567.1\|WP_025328544.1\|14399_14717_+\|DUF496-family-protein	gnl\|CDD\|180070	PRK05423, PRK05423, DUF496 family protein.	6.31657e-53
NZ_CP007567.1\|WP_005327748.1\|2840_3359_-\|tyrosine-protein-phosphatase	gnl\|CDD\|350355	cd14505, CDKN3-like, cyclin-dependent kinase inhibitor 3 and similar proteins. This family is composed of eukaryotic cyclin-dependent kinase inhibitor 3 (CDKN3) and related archaeal and bacterial proteins. CDKN3 is also known as kinase-associated phosphatase (KAP), CDK2-associated dual-specificity phosphatase, cyclin-dependent kinase interactor 1 (CDI1), or cyclin-dependent kinase-interacting protein 2 (CIP2). It has been characterized as dual-specificity phosphatase, which function as a protein-serine/threonine phosphatase (EC 3.1.3.16) and protein-tyrosine-phosphatase (EC 3.1.3.48). It dephosphorylates CDK2 at a threonine residue in a cyclin-dependent manner, resulting in the inhibition of G1/S cell cycle progression. It also interacts with CDK1 and controls progression through mitosis by dephosphorylating CDC2. CDKN3 may also function as a tumor suppressor; its loss of function was found in a variety of cancers including glioblastoma and hepatocellular carcinoma. However, it has also been found over-expressed in many cancers such as breast, cervical, lung and prostate cancers, and may also have an oncogenic function.	1.04647e-42
NZ_CP007567.1\|WP_025325515.1\|3519_3990_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	4.77279e-36
NZ_CP007567.1\|WP_005327752.1\|5322_6474_-\|benzoate/H(+)-symporter-BenE-family-transporter	gnl\|CDD\|281578	pfam03594, BenE, Benzoate membrane transport protein.	1.29045e-140
NZ_CP007567.1\|WP_041204871.1\|427_1666_-\|HD-GYP-domain-containing-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	4.48404e-54
NZ_CP007567.1\|WP_005327754.1\|7162_8359_-\|NnrS-family-protein	gnl\|CDD\|377571	pfam05940, NnrS, NnrS protein. This family consists of several bacterial NnrS like proteins. NnrS is a putative heme-Cu protein (NnrS) and a member of the short-chain dehydrogenase family. Expression of nnrS is dependent on the transcriptional regulator NnrR, which also regulates expression of genes required for the reduction of nitrite to nitrous oxide, including nirK and nor. NnrS is a haem- and copper-containing membrane protein. Genes encoding putative orthologues of NnrS are sometimes but not always found in bacteria encoding nitrite and/or nitric oxide reductase.	1.45802e-93

>NZ_CP007567.1|WP_041204871.1|427_1666_-|HD-GYP-domain-containing-protein
MTGIKISVDRLQVGNYVSLPLGWREHPFLFSSFKLKSEEEIELIRRLGLKLVTIIPDKSDAPPKPLDQVQPAPDGSDDLVGRQQEMQQEKTRRIEQLQRYRRDLQQCEKHFQQSLAQVRNLMGKIQSRPLNAINEAQELINAMTEQLLSVDEMVLHLVSDSADGNNLQFHSLNVSVLSMLLARECKLPAEAIRQVGMGALFHDIGKLKIPSQILRKTGPLTKPEQNLMAQHPRYGLELLSLTSGFPEPAKRIVQYHHEYLDGSGPQGLRGDQLDPLTQIVSLINEYDNLCHLQAKVPYSALGNLYKQRKGQFNADHLGMLIRLMGIYPPGSVVQLSNGQVGLVMSVNASRLLYPAVLVYDPRIPRQEAAIIDLEQAELTIAKVIHPKRLPPAVFEYLNPRTRISYYFEHNKP
>NZ_CP007567.1|WP_005327748.1|2840_3359_-|tyrosine-protein-phosphatase
MLSAHPFWSLEVPRLDGQLLLTPCPGNQQVAMPLALAQLQLAGAGGVLTLMTKDELAARGASSLGSQVKARGMAWFHLPIADDEAPDEAFEQAWLSVLPQLISLLREGRHLAIHCHGGSGRTGLVAALLLMAQGQPQLEAMATIRARRPGAFTLACHRHWLDTRGRRLAGAD
>NZ_CP007567.1|WP_025325515.1|3519_3990_+|Lrp/AsnC-family-transcriptional-regulator
MRNLDQLDLDILAHLFRDAGMTNKDLAALVGVAPSTCLERVRKLQQDGVLKGAHCEVDYQALGGHIQAMVSLQLARHSRQIIDAFRDAILALPEVISLFHMGGKDDFLVHLCVADTEHLRNFVFDHFTSREEVVHLETSLVFEHRFSRSLPCFTHP
>NZ_CP007567.1|WP_041204874.1|4110_5175_-|DUF3103-family-protein
MRNQAVILLLTLLGTASAYAADTDRELARQLALQQKNLLPLLANQEYQSPLPNLLQKASPRLKRQANDANQAAISRQGLDGEIKQLMQLRLANPEQAAALQQGVDPLVAYVPSGDEKSWSAIEAFDSAGNPVYLDVNQPPARPVLVVEADPVKAKNAGLKVMRKALAAADMQVAPRVTGNTAPLKTSILKKIRLSDDQEPWLLGAAEVYAVVAGVNPGRDEPVVDIVDMPYLDHDNTDYTPNQILVYWDRYRWGAVDLVMMEQDDNVNYKELSALLIEALKLGFTAGGVPEALPFLDLGGRIVKALPDSWMTNNDDYLDTFYTLEQDQSYHQYPGAAGNAVITLEPKEIQPTRP
>NZ_CP007567.1|WP_005327752.1|5322_6474_-|benzoate/H(+)-symporter-BenE-family-transporter
MPFAFPHLVAGLIAVLVGYTSSVVLIIQAATAAGADAAQVSSWLWTLGIGMGVSCIGLSLYYRIPVLTAWSTPGAALLITSLGNFSLSEAIGAFIASSLLITLCGISGWFDRLMRHIPAPLAAAMLAGVLLRFGLDLFKVAPQDPLLLGASLLAFLLGRHLWPRYTMVLILSAGMLLCTLRGELQLAEVHWQLSSPVWITPTFSINALLGIALPLFIVTMTSQNMPGITILRAHGYQPATSSLIGWTGLTGLLLAPFGGYAFNLAAITAAICMGKEVDPDTARRWPAAVWAGCFYLLTGCFGATVVALFSAFPTALVTCVAGLALLGTIGSSLHAALQQDEEREAALLTFLITASGISLLGVGSACWGLLVGVALHQVNRLRA
>NZ_CP007567.1|WP_005327753.1|6589_7159_+|helix-turn-helix-transcriptional-regulator
MQEMNRHLAQRLKGLRSELGWSLDVAARETGVSKAMLGQIERGESSPTVATLWKIATGFRVSFSSFIEPTPAVAGETLYRTADDIRQQPAGEGMQVAPLFPYEGRFGFELFELTLLPGYQRESEPHETGVTEHVIVISGVMEVLVDGQWRSLEQGEAVRFVADRPHGYRNLGIAPAVFHNLIHYPATRA
>NZ_CP007567.1|WP_005327754.1|7162_8359_-|NnrS-family-protein
MHQILDSHKEEQIVPLFRLGFRPFFLLGALFSCLAMLGWLGQLNGWFALPGIGNPIWWHAHEMLFGFGAAIVAGFLLTAVQNWTAHPGVRSWPLALVVGLWALPRCLLPWLGEDNIILMALDLAWLPLCAWFLAKPIIMTRQWRNLFFVPLLLILTLLNGATWLWRDDWNTVEHLLITTVLLFTTLIAVMGGRVIPFFTARGTGQEKAPPRPWLERGALASLWLILLLWLLLPGSWANSLYTMPLYIVAAGLHLCRQLRWQPGDTLAHPLLWSLHLAYLFIPLGLLALTAQAAGLPLSLSLASHLLSAGCMGTMILGMIARVSLGHSGRALHVGRRITMAFALVIVSALVRVLIPLYWPTLTLTGWNLSGWSWIAAYGLFVWVYTPILTRPRVDGRPG
>NZ_CP007567.1|WP_025328544.1|14399_14717_+|DUF496-family-protein
MEQVNKSTFSDVLEYVRMSRRQNKLKREIADNEKKIRDNQKRVLLLDNLSDYIKPGMSIDEVQAIIANMRTDYEERVDDHIIKNAELSKERKELSTKLKGMSTSK
>NZ_CP007567.1|WP_041204875.1|14931_18015_+|penicillin-binding-protein
MGASKQTDSNKVASQDSSVPHADGQYQRKRRPWWRWLFCFIFLLCLAAVIALVGYEMKTSRLQSQEISRYAAKLTYELEPGPSKQITFPDDGPFDKRLGYVLMPMIQERLIQRGYQVSEQVRFSDALYNYASHGFFVPYTEKVQAGLTLHDCRAEPFYQYKYPTHYYPDFNSIPPLVIQSLLFIENRELLSNEQPLANPAVDWPRFAKAALSQVGKALDMQDQSAGGSTLATQVEKYRHSPDGLTLSPTEKIRQMASASVRAYRLGPKTLEARKLVAWAYLNSVPLSAAPGYGEVHGLGDGLWVWFGADVDEVNRLLDPARNQDATLAEQGLALRQVVSLMIAHRRPSYYLAQGREALSTLTDSYLRLFVQEGMITPPLMESALKAKLAFRDFLQAPAITRVNNNKGLQVARTRLSRQLGVQLYDLDRMDLTADTTLNMPLQNDVSRYLQQLADPTFAAQVGLFGERLLSPEKTGDVKYSFTLFEKTPEGVKVRVQTDNTDQPFDINEGSKLELGSTAKLRVLTTYLEIVTELHDSYGNMPAESLRKIEVSDQDNISRWAIAYLMSAKDKSLPVMLEAALDRKYSASPYEGFFTGGGMHTFNNFRKEDNGRIPPIRDALRESINLPFVRLMRDIVRYSLYKEGNRAQLLKDDKDPRRTEYLAKFADKEGQTYLLRFWRKYRGKTTDEQLDTFLDGLKPSAVRLAAVHRYLMPEASQADFAAFLAKRLPRDKLSDKRVEQLYTSYGPGKYSLPDQGYIARVHPLELWLLSYLREFDKATFADAVAASRDERQEVYSWLFKTRHRSARDSRIRTMLEVEAFLDIHQRWARLGYPFDHLVPSLATALGSSGDRPAALAELMGIIQNGGMRAPTLRIEHLSFAKDTPFATVFEPANTQGVRVMPAEVANALRNALSKVVEGGTARRIAGAFALQDGTVLSLGGKTGTGDNRIETVGRYGNVTSSLARNRTATFVFYIGDDHFGTLTAYVPGSQSDKFRFTSALPVQVLKGMAPLLVPYLQPGTHTQCLPGS
>NZ_CP007567.1|WP_005331314.1|18082_18607_-|ribosome-associated-protein
MSQYQDDNELDDWGPSKSQLKRDAEALQKLGAEIVSLSHSELERIPLDEELAEAVELGRKLKPKKDESFRRHLQFIGRLMRSRDIEQIEEALSIIKMRHSTVNARLHRLEQWRERLITEGDSALNELMSQFHELDRQKLRQLIRTANKERELNKPPVAYREMYQYLRGEIEDQL
>NZ_CP007567.1|WP_005331315.1|18718_20062_+|metalloprotease-PmbA
MDQQDQIRQDQAHLEAVVAEALEIAKGLGAGLAEVSISKQTGLSVNTRGCELESIEFNKDGALGIAVYRNGCKGSSSTTDLGKPAIRAAVEAAMEIARHTSPDEYAGLADAELLAWDAPDLQLCHSIELDPQRGIELAIECERLALGRDARIKHSDGASFSSHLGVKVYGNSHGFVKGYAASRNSLSCVLIGEQDGDMQRDYGYSSSRALSGLWSPQRIADEAVERTVSRLGARKISTRHAPVLFHPDTAAGLWGHLVMAISGGNLYRKSSFLLDKLGKQILPEWLSIQEFPHLLGGLASTPFDGEGVRTRDMDIVRNGELMSWLLTSYSARKLGLTTTGHAGGIHNWQVSNTGQDFQGMLKEMGTGLLVTELMGQGVNIVNGDYSRGAAGFWVENGEILYPVEEITIAGNLADMFSTLVAVGNDEDERSSLKTGSVLVEQMKLAGH

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Crispr_ID: NZ_CP007567_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_2

1044390-1044486

TypeV

Consensus_repeat	Method
GCTCAAGGGCTGATACCCCGCCAGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_2

>merge|NZ_CP007567|2|1044390-1044486|CRISPRCasFinder
GCTCAAGGGCTGATACCCCGCCAGCGCCAAAAGCCCGCCTGGCCTTGGAGGGCTTCACCATTGTGGCTGGCGCTCAAGGGCTGATACCCGCCAGCGA

>NZ_CP007567|2|2|1044390-1044486|CRISPRCasFinder
GCTCAAGGGCTGATACCCCGCCAGCG	CCAAAAGCCCGCCTGGCCTTGGAGGGCTTCACCATTGTGGCTGGC
GCTCAAGGGCTGATACCCGCCAGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_081805658.1\|1048245_1048734_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|377396
NZ_CP007567.1\|WP_005327197.1\|1041558_1042449_+\|protoheme-IX-farnesyltransferase	unknown	unknown	gnl\|CDD\|184001
NZ_CP007567.1\|WP_005327195.1\|1041215_1041545_+\|cytochrome-o-ubiquinol-oxidase-subunit-IV	unknown	unknown	gnl\|CDD\|182568
NZ_CP007567.1\|WP_041205384.1\|1036341_1037439_+\|ISAs1-like-element-ISAeme2-family-transposase	unknown	unknown	gnl\|CDD\|379382
NZ_CP007567.1\|WP_041205387.1\|1042614_1043976_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341025
NZ_CP007567.1\|WP_041205386.1\|1038623_1040600_+\|cytochrome-o-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|131890
NZ_CP007567.1\|WP_005326900.1\|1034293_1034737_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|225039
NZ_CP007567.1\|WP_005326901.1\|1033264_1034173_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP007567.1\|WP_081805657.1\|1037546_1038620_+\|cytochrome-o-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|182518
NZ_CP007567.1\|WP_041205389.1\|1045998_1047102_-\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|99750
NZ_CP007567.1\|WP_005332143.1\|1049451_1049694_-\|DUF3297-family-protein	unknown	unknown	gnl\|CDD\|371696
NZ_CP007567.1\|WP_041204928.1\|1051918_1053046_-\|ISAs1-like-element-ISKpn9-family-transposase	unknown	unknown	gnl\|CDD\|379382
NZ_CP007567.1\|WP_019706001.1\|1035194_1036142_-\|IS30-like-element-ISAs2-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP007567.1\|WP_005332142.1\|1049792_1051109_-\|HipA-domain-containing-protein	unknown	unknown	gnl\|CDD\|341494
NZ_CP007567.1\|WP_081805857.1\|1040520_1041216_+\|cytochrome-o-ubiquinol-oxidase-subunit-III	unknown	unknown	gnl\|CDD\|182628
NZ_CP007567.1\|WP_019706001.1\|1053185_1054133_-\|IS30-like-element-ISAs2-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP007567.1\|WP_041205391.1\|1048744_1049173_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|377396
NZ_CP007567.1\|WP_041205253.1\|1044537_1045875_-\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP007567.1\|WP_005332127.1\|1047251_1048145_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NZ_CP007567.1\|WP_049832154.1\|1051092_1051389_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|213767

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_081805658.1\|1048245_1048734_+\|DMT-family-transporter	gnl\|CDD\|377396	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ. DMT_YdcZ is a family of putative inner membrane exporters from both Gram-positive and Gram-negative bacteria.	5.46678e-21
NZ_CP007567.1\|WP_005327197.1\|1041558_1042449_+\|protoheme-IX-farnesyltransferase	gnl\|CDD\|184001	PRK13362, PRK13362, protoheme IX farnesyltransferase; Provisional.	5.93149e-139
NZ_CP007567.1\|WP_005327195.1\|1041215_1041545_+\|cytochrome-o-ubiquinol-oxidase-subunit-IV	gnl\|CDD\|182568	PRK10582, PRK10582, cytochrome o ubiquinol oxidase subunit IV; Provisional.	1.72324e-54
NZ_CP007567.1\|WP_041205384.1\|1036341_1037439_+\|ISAs1-like-element-ISAeme2-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	7.06729e-27
NZ_CP007567.1\|WP_041205387.1\|1042614_1043976_+\|MFS-transporter	gnl\|CDD\|341025	cd17472, MFS_YajR_like, Escherichia coli inner membrane transport protein YajR and similar multidrug-efflux transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli inner membrane transport protein YajR and some uncharacterized multidrug-efflux transporters. YajR is a putative proton-driven major facilitator superfamily (MFS) transporter found in many gram-negative bacteria. Unlike most MFS transporters, YajR contains a C-terminal, cytosolic YAM domain, which may play an essential role for the proper functioning of the transporter. YajR-like transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.3744e-158
NZ_CP007567.1\|WP_041205386.1\|1038623_1040600_+\|cytochrome-o-ubiquinol-oxidase-subunit-I	gnl\|CDD\|131890	TIGR02843, Cytochrome_bo3_ubiquinol_oxidase_subunit_1, cytochrome o ubiquinol oxidase, subunit I. Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain which reacts with oxygen, reducing it to water with the concomitant transport of 4 protons across the membrane. Also known as the cytochrome bo complex, cytochrome o ubiquinol oxidase contains four subunits, two heme b cofactors and a copper atom which is believed to be the oxygen active site. This complex is structurally related to the cytochrome caa3 oxidases which utilize cytochrome c as the reductant and contain heme a cofactors, as well as the intermediate form aa3 oxidases which also react directly with quinones as the reductant. [Energy metabolism, Electron transport].	0
NZ_CP007567.1\|WP_005326900.1\|1034293_1034737_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	9.86317e-21
NZ_CP007567.1\|WP_005326901.1\|1033264_1034173_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.26869e-78
NZ_CP007567.1\|WP_081805657.1\|1037546_1038620_+\|cytochrome-o-ubiquinol-oxidase-subunit-II	gnl\|CDD\|182518	PRK10525, PRK10525, cytochrome o ubiquinol oxidase subunit II; Provisional.	0
NZ_CP007567.1\|WP_041205389.1\|1045998_1047102_-\|YdcF-family-protein	gnl\|CDD\|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	1.26894e-26
NZ_CP007567.1\|WP_005332143.1\|1049451_1049694_-\|DUF3297-family-protein	gnl\|CDD\|371696	pfam11730, DUF3297, Protein of unknown function (DUF3297). This family is expressed in Proteobacteria and Actinobacteria. The function is not known.	1.11664e-44
NZ_CP007567.1\|WP_041204928.1\|1051918_1053046_-\|ISAs1-like-element-ISKpn9-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	4.2722e-34
NZ_CP007567.1\|WP_019706001.1\|1035194_1036142_-\|IS30-like-element-ISAs2-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.20844e-94
NZ_CP007567.1\|WP_005332142.1\|1049792_1051109_-\|HipA-domain-containing-protein	gnl\|CDD\|341494	cd17809, HipA_So_like, type II toxin-antitoxin sytem toxin HipA from Shewanella oneidensis and similar proteins. This family contains type II toxin-antitoxin (TA) system HipA family toxins similar to Shewanella oneidensis HipA, a serine/threonine-protein kinase that phosphorylates Glu-tRNA-ligase (GltX), preventing it from being charged, leading to an increase in uncharged tRNA(Glu). This induces amino acid starvation and the stringent response via RelA/SpoT and increased (p)ppGpp levels, which inhibits replication, transcription, translation and cell wall synthesis, reducing growth and leading to persistence and multidrug resistance. HipA is the toxin component of the HipA-HipB TA module that is a major factor in persistence and bioflim formation; its toxic effect is neutralized by its cognate antitoxin HipB. HipA, with HipB, acts as a a corepressor for transcription of the hipBA promoter. In the Shewanella oneidensis HipAB:DNA promoter complex, HipB forms a dimer that binds the duplex operator DNA, with each HipB monomer interacting with separate HipA monomers. The HipAB component of the complex is composed of two HipA and two HipB subunits.	4.36737e-159
NZ_CP007567.1\|WP_081805857.1\|1040520_1041216_+\|cytochrome-o-ubiquinol-oxidase-subunit-III	gnl\|CDD\|182628	PRK10663, PRK10663, cytochrome o ubiquinol oxidase subunit III; Provisional.	2.10664e-130
NZ_CP007567.1\|WP_019706001.1\|1053185_1054133_-\|IS30-like-element-ISAs2-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.20844e-94
NZ_CP007567.1\|WP_041205391.1\|1048744_1049173_+\|DMT-family-transporter	gnl\|CDD\|377396	pfam04657, DMT_YdcZ, Putative inner membrane exporter, YdcZ. DMT_YdcZ is a family of putative inner membrane exporters from both Gram-positive and Gram-negative bacteria.	2.46704e-13
NZ_CP007567.1\|WP_041205253.1\|1044537_1045875_-\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	5.62528e-32
NZ_CP007567.1\|WP_005332127.1\|1047251_1048145_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.40185e-95
NZ_CP007567.1\|WP_049832154.1\|1051092_1051389_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|213767	TIGR03070, couple_hipB, transcriptional regulator, y4mF family. Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions].	6.91696e-07

>NZ_CP007567.1|WP_041205387.1|1042614_1043976_+|MFS-transporter
MNDFTMTRGERRATWALGSVFSLRMLGMFMVLPVLTTYGMSLAGASEALIGLAIGIYGMTQALFQIPFGLLSDRIGRKPLIVGGLLMFAAGSVIAALSDSIWGVIVGRALQGSGAISAVVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVTGPLITQAVGLSGLFWLIALLALAAIAMVIWVVPTPAAHLQNRESAMVRGGFRTVLTNPRLLKLNLGILCVHTLLMSSFVALPPLLEQAGLAREQQWQAYLVTMLVAFVSVVPFIIYAEKHRQMKRVFIGCVLVMLAAELVLWQAGLQLWGLLAGLQLFFVGFNVMEALLPSLISKESPPGYKGTAMGVYSTSQFLGVAIGGSLGGLLYSLGGGPLVFGGCAVLALLWFGVSLTMAEPPYVSSLRIVLPEGVEATPALEQRIRACDGVSDVLLVREEHSLYVKVDSKRLTRSDLERLVSL
>NZ_CP007567.1|WP_005327197.1|1041558_1042449_+|protoheme-IX-farnesyltransferase
MMKQYLQVTKPGIIFGNLISVIGGFLLASKGSLDVPLFILTMVGVSLVVASGCVFNNYIDRDIDCIMERTKNRALVRGLIAPGVSLWYATALGVAGIALLYFAANPLAALLAVLGFLVYVGVYSLYMKRHSVYGTLVGSLSGAAPPVIGYCAVSGQFDSGALILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKHHITLYILAFMVPTLMLFLGGYAGYKYLIVATAVSVWWLGMALSGYKAAVDDSLWARKLFMFSIVTITCLSVMMSVDFQPDAAPVLVSMLP
>NZ_CP007567.1|WP_005327195.1|1041215_1041545_+|cytochrome-o-ubiquinol-oxidase-subunit-IV
MSHSVDNHGASHGSVKSYMTGFVLSLILTAIPFWMVMDGSASHAMVLGTVVGMAVVQIFVHLIYFLHMNTSSEERWNLVALVFTVLIIAIVVVGSLWIMYNLNINMMVH
>NZ_CP007567.1|WP_081805857.1|1040520_1041216_+|cytochrome-o-ubiquinol-oxidase-subunit-III
MWTTTYRLTRSSASKVSISTISTRWLNSMATDVLHHTHGAHEDGHHDAGATKVFGFWIYLMSDCILFATLFATYAVLVNGTAGGPTGKDIFELPFVFAETMLLLLSSITFGFGMLAMNKNKVSAVNTWLLVTFLLGAGFIAMEIYEFHHLIVNDAGPDRSGFLSAFFTLVGTHGIHVTSGLIWIIVMMVLISKKGLTERNRTRLMCLSLFWHFLDVVWICVFTVVYLMGVM
>NZ_CP007567.1|WP_041205386.1|1038623_1040600_+|cytochrome-o-ubiquinol-oxidase-subunit-I
MFGKLTLEAVPYHEPIIMVTIACIILGGLAIAGLITYYGKWQYLWKEWFTSVDHKRLGIMYLILGMVMLLRGFADAVMMRGQQVMASAGSEGYLNAHHYDQIFTAHGVIMIFFVAMPLVIGLMNIVVPLQIGARDVAFPFLNNLSFWFTAAAVVLINVSLGVGEFAQTGWLAYPPLSGLEFSPGVGVDYWIWSLQISGLGTLLTGVNFFATIIRMRAPGMTMMRLPVFTWTALCANILIIASFPILTVTIALLTADRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILVLPVFGIFSEVVATFCKKKLFGYTSLVWATVAITVLSFVVWLHHFFTMGSGANVNAFFGITTMIISIPTGVKIFNWLFTMYRGRIEFSSPMLWTVGFIITFTVGGMTGVLLSVPAANFVLHNSLFLIAHFHNVIIGGVVFGCFAGITYWFPKAFGFKLDDVWGKRAFWFWITGFFVAFMPLYVLGFMGMTRRVSQNIDPEFHGWLVVAACGAGLIAIGVLCQLIQVVVSIRDREKNRDWTGDPWGGRTLEWATSSPPPFYNFAIEPKVTGLDAFWEAKEDGSAYRQPAKYAPIHMPKNSGAGVIIAAFSVVFGFAMIWHIWWMAIAGFVGMIATWIIHSFNDDVDYYVQVDEIERIEGQHFDNINKVA
>NZ_CP007567.1|WP_081805657.1|1037546_1038620_+|cytochrome-o-ubiquinol-oxidase-subunit-II
MRPFEVKRGLGALLLMATAGLLSGCDMALMSPKGQVGLEQKSLILTALGLMLIVVIPVIIMTVAFARKYRASNTTAKYTPDWSHSNKIEAVVWTVPVIIVAILAVITWKTSHSLDPYKPLESDVKPIQVDVISLDWKWLFVYPELGIASVNELAFPVNTPINFRVTSDTVMNSFFIPQLGGQIYAMAGMQTKLHLIANEAGQYKGISGSYSGAGFSGMKFKAIATQDQAGFDAWVAKVKQSPKMLSTMGEFDALAKKSENHPVEYFASADPKLFVNVINKFMGGMSHGGHDAAKDGAMDHEAMKHDAAKAEPMDHKAMNHDAAKAESMDHAAMSHDEHAGHMATSMADKSVKAGSEE
>NZ_CP007567.1|WP_041205384.1|1036341_1037439_+|ISAs1-like-element-ISAeme2-family-transposase
MTLIEHLTLVEETRSDINRKHDLVDVMFLVISAIISGAEGWRDIETYGNSKADWLRQYRPFANGIPRRHTIARILRCIVIDTLLEALLCWVNEQRTHQGKPIIAFDGKVLRGSFRGNAKDALQLVTAYDTENGLVLSQKATPNKKGEIETVKEMLDILELKGAVVTLDALHCQRETLQKISEKKAHVVVQVKKNQPKLYQAVQSQFQALFDAQKEKIVVEHKESGHGRQEERYVFQLKAKLPPELAEKWPTIRSIIAVERHRSANGKGTVDTSYYVSSLSPKHKLLGHYIRQHWRIENSQHYILDMVFNEDASRIAMEDAVENMALFRRFVLNIVKQSDCGAPSQRNKLKKASWDDNYRAQLFFG
>NZ_CP007567.1|WP_019706001.1|1035194_1036142_-|IS30-like-element-ISAs2-family-transposase
MSYQQLTEGQRYQLSVLRAQGMSILATARAIGVHRSTLYRELRRNAGPQGYQPDNAHQHATHRRASAAKSRLSADVIQFVELTLAWWWSPEQISAVGKQIGLMVSHEWIYRHVAADKARGGQLYRHLRQGHKRYRKGASSLRSPIKEARSIDERPAIVDSRERLGDWEADTVLGKQGTGALVTLVERKSRLYLVKRVASKQAGVVRDAIIEMLTPYIEQVHTITFDNGGEFAEHKAIEEALGAETYFAHPYSSWERGLNENSNGLLRQFIPKGTDLREVTDEDVRRAEQWLNLRPRKCLGFRQPVKVFEEYRQAA
>NZ_CP007567.1|WP_005326900.1|1034293_1034737_+|carboxymuconolactone-decarboxylase-family-protein
MSDRIQLASQVPAAVSAMMGLEAYLGGTDIPLSLKELIKLRASMLNGCAYCIEMHAEVAMKHGDSPQRLLALAAWRESPLFDERERAVLALTDEVTLIGERGLTEETYQQALALLGDTLLAQCLMQVVTINAWNRIAVATRMEHKHP
>NZ_CP007567.1|WP_005326901.1|1033264_1034173_-|LysR-family-transcriptional-regulator
MLDRVRILAQVVESGSFSRAARALNLAPSSVTRTIDALEQQLGIPLFKRSTRQLVLTEQGEYFLARSARLLEEADQLVQSLQPLPVAPEGPLRVSVFESFGAAWLAPRLPAFLARYPGVRLEIELDNRLVDLDAENVDVAVRIGRPVDSGLHARHLLTNRTLLVASPAYLARHGEPAHPDELAHHNCLIRGHGRQRQHWYFRQGAQRHRVAVRGNLASVGGTPLLCAAQAGTGILLLSSWMVQQGIDDGTLQPLLPDWQASPYEDRHDEIHAVFRGGRFLKPQTRAFIDFLIEVMAPLQVPR
>NZ_CP007567.1|WP_041205253.1|1044537_1045875_-|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNEPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIEKRPRPSRPRAVKISKTRFPVNRNAAPLK
>NZ_CP007567.1|WP_041205389.1|1045998_1047102_-|YdcF-family-protein
MKKTAIALTLTSLLTLPLVVSSDAWAAPVRSLQKEQNYEQFISKRQVVDQLLADAARIFHSPARVSDAGFTAKMPSNMEQVTTLLLEAHQLEPYRTDLLISAANAQIYNGNVERAIALFEQALTAAPDDLDINTYLATWLRFKGDQTKSDGYVKRVVELNAGRAADLQRLFATVDRVVATPLKERQGRGEKKGRRAIVTLGYALNPDGSMNDILLGRLETTRALAQADPAALVILTGGVPQNRQTEGKLMADWLAKKGIDRSRIIEENYATSTVENALYSGYALARHEIEYATLVSSASHVRRGQTLLEIACWQSGPANIRIDSVAYPDKPLSALAKASPEELLGIYRDALRTYGLWSYRSAPLIER
>NZ_CP007567.1|WP_005332127.1|1047251_1048145_-|LysR-family-transcriptional-regulator
MNQDAFALLPAFVAVVESGSFSGAARQLGLSKSVLSKKVSQLEQALGCQLIYRTTRSLTLTEAGERYFETVRHAVRLASDGEDAIGALQSAPRGLLRVTVPMVYGRRHIAPLVPEFLALHPEVQLQLEMSDAQQDLVAEGFDVAVRIGELEDSSLVARRLAPCLSTLCAAPAYLAQAGTPHTPADLERHNCLFYSLFRGGTQWRLHGPEGEVAITPRGNFEVNNSDAIHTALLAGLGIGNMPDFIVARDLAAGRLVPVLPGHALPEHGVWCVYPRRRHLPAKVEAWLAFLQERLGLR
>NZ_CP007567.1|WP_081805658.1|1048245_1048734_+|DMT-family-transporter
MIPPLVDRGPGRPALGQTLGQTLGALAAFAAGLLLALMIAQNGALARATDPWLGSWLAHGVGTLVAALLWWLSPRPPTPEAAPPWAWLGGLPGALTVVLAALCLNSSLGMAGTLALLLLGQLLFGALCDGLGWLGLARRRPSGKDALAALLVMAGALLIVLG
>NZ_CP007567.1|WP_041205391.1|1048744_1049173_+|DMT-family-transporter
MTILILLGLLNGVAVSLSRTLNGRLASARGAMTASLANHLLGFGLLGALLILKGAPWERLAGLDPWLLLGGVLGALFVAISSWAIGRVGALACALLIVTGQLAGGALLDALAGRLAASDLLGILLVLAGAALQRWQAGKPRS
>NZ_CP007567.1|WP_005332143.1|1049451_1049694_-|DUF3297-family-protein
MSDNKPALPDRLAANPRSPHHVAECFQHEIGIRVNGKERTNVEEYCISEGWVKIPSPKAKDRYGNAMLITVKGTVEAFYA
>NZ_CP007567.1|WP_005332142.1|1049792_1051109_-|HipA-domain-containing-protein
MMSGSERHRLELRLGNQLIGHLEYDSQRDTFQLGYTPAWQARGFPISPPLALDGSASSAQIRAYLGNLLPENRGLEHLIEALSVSRSNLFALIHGIGRDVSGAVTFTLPAEPDIPTHFRPITPEELMLRLDQPELWPLEVWDGRPRLSVAGVQAKLNLLRLEGALGFGEGEICSTHLLKFEHHPHLVINEFVTMRLAALLGMPVAQVELHRVGQGDKSHRGLLVERFDRRLDEDGLRVRRRHMIDACQGLGFPVTRKYERNFGDGRDVAHIREGVSLPRLFSLSVLCVNPAQARLDMLQWLLFNLCVNNHDAHGKNYSFFVSKAGLMPTPWYDLVNVGLYPEFNQHLAMAIGDEFAPEAVNAWQLLEMAEACDLPKRLLQQTLHKVASDILHQLDAAIALVETDNPAELAYLARYRDDVERRCHHFQEQATLLPELQR
>NZ_CP007567.1|WP_049832154.1|1051092_1051389_-|helix-turn-helix-domain-containing-protein
MMADASLQTGPKELDPASLGLAIRERRKAARMTQEVTASLCGISKKTLIKIEKGGDVYLSTLLQVMNALGLRLQLVQEAGSQVTSDSSQSEVGDDEWF
>NZ_CP007567.1|WP_041204928.1|1051918_1053046_-|ISAs1-like-element-ISKpn9-family-transposase
MAQKSLLDYLESIPDPRNQAKCSHILSEVVFMAICAMMCGFDTWSEITLFAQEREPWFRRWLSLPGGIPSHDTFNRIFATLPPASLKSIFQAWIGDIMGDDKLVGQLAVDGKALRATAKGRGANAVHMVNVWSTELGMCVGQQKVADKSNEITAIPELLQLLELKGCLVSIDAMGTQVKIADTILKKSGDYLLAVKDNQPSLNTEVKEQFQAYWDKNETDVSGHGFTEQFDSEHGRKEHRRCWVLMVDESMPVCQQWKAKTIIAVQAERIENGKGYDFVRFYISSRALDATSALKATRAHWSVENLLHWTLDIAFGEDQLQARAGFAGENLAVIRQWILNMLKQNKSRNLSMANKRRLCCLNEQYLFECMGLFKV
>NZ_CP007567.1|WP_019706001.1|1053185_1054133_-|IS30-like-element-ISAs2-family-transposase
MSYQQLTEGQRYQLSVLRAQGMSILATARAIGVHRSTLYRELRRNAGPQGYQPDNAHQHATHRRASAAKSRLSADVIQFVELTLAWWWSPEQISAVGKQIGLMVSHEWIYRHVAADKARGGQLYRHLRQGHKRYRKGASSLRSPIKEARSIDERPAIVDSRERLGDWEADTVLGKQGTGALVTLVERKSRLYLVKRVASKQAGVVRDAIIEMLTPYIEQVHTITFDNGGEFAEHKAIEEALGAETYFAHPYSSWERGLNENSNGLLRQFIPKGTDLREVTDEDVRRAEQWLNLRPRKCLGFRQPVKVFEEYRQAA

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Crispr_ID: NZ_CP007567_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_3

1226636-1226737

Orphan

Consensus_repeat	Method
GTCCGCCGTTCTACCGACTGAACTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_3

>merge|NZ_CP007567|3|1226636-1226737|CRISPRCasFinder
GTCCGCCGTTCTACCGACTGAACTACGAGGGAATTGGCTCCTCCCAAGGACTTTAACCCGTTATCTACGGATTGGATGTTCGCCGTTCTACCGACTGAACTA

>NZ_CP007567|3|3|1226636-1226737|CRISPRCasFinder
GTCCGCCGTTCTACCGACTGAACTA	CGAGGGAATTGGCTCCTCCCAAGGACTTTAACCCGTTATCTACGGATTGGAT
GTTCGCCGTTCTACCGACTGAACTA

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_005327660.1\|1236281_1236728_-\|DUF2787-family-protein	unknown	unknown	gnl\|CDD\|371323
NZ_CP007567.1\|WP_010674210.1\|1227204_1228818_-\|IS1634-like-element-ISAs25-family-transposase	unknown	unknown	gnl\|CDD\|227708
NZ_CP007567.1\|WP_005327418.1\|1215969_1217394_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|235967
NZ_CP007567.1\|WP_012564931.1\|1232525_1233473_+\|IS30-like-element-ISAeca1-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP007567.1\|WP_005327429.1\|1223933_1224860_-\|alpha-E-domain-containing-protein	unknown	unknown	gnl\|CDD\|377234
NZ_CP007567.1\|WP_041205479.1\|1221850_1222336_-\|YqhA-family-protein	unknown	unknown	gnl\|CDD\|179964
NZ_CP007567.1\|WP_041205484.1\|1231697_1232210_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_005327430.1\|1224853_1226290_-\|circularly-permuted-type-2-ATP-grasp-protein	unknown	unknown	gnl\|CDD\|225190
NZ_CP007567.1\|WP_005327427.1\|1223136_1223937_-\|transglutaminase-family-protein	unknown	unknown	gnl\|CDD\|224224
NZ_CP007567.1\|WP_005327636.1\|1234748_1235975_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271177
NZ_CP007567.1\|WP_041205476.1\|1218303_1221273_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271332
NZ_CP007567.1\|WP_005327419.1\|1217479_1218304_-\|FTR1-family-protein	unknown	unknown	gnl\|CDD\|272930
NZ_CP007567.1\|WP_019706001.1\|1238073_1239021_-\|IS30-like-element-ISAs2-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP007567.1\|WP_005327417.1\|1215268_1215829_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_005327664.1\|1237299_1237824_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_005327426.1\|1222418_1223120_-\|peptidase	unknown	unknown	gnl\|CDD\|239734
NZ_CP007567.1\|WP_049832157.1\|1229851_1231633_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367375
NZ_CP007567.1\|WP_005327423.1\|1221277_1221727_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_005327662.1\|1236794_1237280_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_049832156.1\|1229021_1229855_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_005327660.1\|1236281_1236728_-\|DUF2787-family-protein	gnl\|CDD\|371323	pfam10980, DUF2787, Protein of unknown function (DUF2787). This bacterial family of proteins has no known function.	2.61005e-38
NZ_CP007567.1\|WP_010674210.1\|1227204_1228818_-\|IS1634-like-element-ISAs25-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	2.45339e-57
NZ_CP007567.1\|WP_005327418.1\|1215969_1217394_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|235967	PRK07208, PRK07208, hypothetical protein; Provisional.	0
NZ_CP007567.1\|WP_012564931.1\|1232525_1233473_+\|IS30-like-element-ISAeca1-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	2.83568e-94
NZ_CP007567.1\|WP_005327429.1\|1223933_1224860_-\|alpha-E-domain-containing-protein	gnl\|CDD\|377234	pfam04168, Alpha-E, A predicted alpha-helical domain with a conserved ER motif. An uncharacterized alpha helical domain containing a highly conserved ER motif and typically found as a tandem duplication. Contextual analysis suggests that it functions in a distinct peptide synthesis/modification system comprising of a transglutaminase, a peptidase of the NTN-hydrolase superfamily, an active and inactive circularly permuted ATP-grasp domains and a transglutaminase fused N-terminal to a circularly permuted COOH-NH2 ligase domain.	2.59389e-104
NZ_CP007567.1\|WP_041205479.1\|1221850_1222336_-\|YqhA-family-protein	gnl\|CDD\|179964	PRK05208, PRK05208, hypothetical protein; Provisional.	3.00021e-24
NZ_CP007567.1\|WP_019706001.1\|1238073_1239021_-\|IS30-like-element-ISAs2-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.20844e-94
NZ_CP007567.1\|WP_005327430.1\|1224853_1226290_-\|circularly-permuted-type-2-ATP-grasp-protein	gnl\|CDD\|225190	COG2308, COG2308, Uncharacterized conserved protein [Function unknown].	0
NZ_CP007567.1\|WP_005327427.1\|1223136_1223937_-\|transglutaminase-family-protein	gnl\|CDD\|224224	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism].	2.019e-41
NZ_CP007567.1\|WP_005327636.1\|1234748_1235975_-\|site-specific-integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.06746e-33
NZ_CP007567.1\|WP_041205476.1\|1218303_1221273_-\|hypothetical-protein	gnl\|CDD\|271332	cd14962, NHL_like_6, Uncharacterized NHL-repeat domain in bacterial proteins. The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.	8.67958e-05
NZ_CP007567.1\|WP_005327419.1\|1217479_1218304_-\|FTR1-family-protein	gnl\|CDD\|272930	TIGR00145, Uncharacterized_protein_slr0964, FTR1 family protein. A characterized member from yeast acts as oxidase-coupled high affinity iron transporter. Note that the apparent member from E. coli K12-MG1655 has a frameshift by homology with member sequences from other species. [Unknown function, General].	4.43003e-37
NZ_CP007567.1\|WP_005327426.1\|1222418_1223120_-\|peptidase	gnl\|CDD\|239734	cd03765, proteasome_beta_bacterial, Bacterial proteasome, beta subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on top of one another forming an elongated alpha-beta-beta-alpha cylinder with a central cavity. The proteasome alpha and beta subunits are members of the N-terminal nucleophile (Ntn)-hydrolase superfamily. Their N-terminal threonine residues are exposed as a nucleophile in peptide bond hydrolysis. Mammals have 7 alpha and 7 beta proteasome subunits while archaea have one of each.	2.94498e-129
NZ_CP007567.1\|WP_049832157.1\|1229851_1231633_-\|hypothetical-protein	gnl\|CDD\|367375	pfam03175, DNA_pol_B_2, DNA polymerase type B, organellar and viral. Like pfam00136, members of this family are also DNA polymerase type B proteins. Those included here are found in plant and fungal mitochondria, and in viruses.	0.000561973

>NZ_CP007567.1|WP_005327430.1|1224853_1226290_-|circularly-permuted-type-2-ATP-grasp-protein
MLPIKPPGPGCYDEMLLADNQFRDHYHAYLSWLHQTDEKSIERKREEADLLFHRVGITFNVYGDGDGAERLIPFDSIPRIIPSREWQHLDKGIRQRVTALNAFLHDIYHDQRILKAGVIPAAQILTNAQYKPCMQGVDLHRNTYVHITGVDIIRNSDGDYYVLEDNLRTPSGVSYMLENRKMMMRLFPELFHNQPIAPVERYPALLLQTLRESSPVDNPCVVVMTPGRFNSAYFEHSFLAQQMGVELVESADLVVKDGQVLMRTTTGLKRVDVIYRRIDDDYLDPLAFNPDSLIGVPGLLSVYRAGGVVLANAIGTGVADDKSIYPYVPEMIRFYLGEEPILNNVPTWQCREPDALTYVLAHLEELVVKEVHGAGGYGMLIGPCASREELARFRELLKARPDNYIAQPTLSLSTCPTFVEAGIAPRHIDLRPFVLTGQELRLVPGGLTRVALTEGSLVVNSSQGGGTKDTWVMEGNPC
>NZ_CP007567.1|WP_005327429.1|1223933_1224860_-|alpha-E-domain-containing-protein
MLSRTASELYWMSRHLERAENTARMLDVTQTMSLMPSIDADHSELVAPLTISGTHEPFLARYGQVNMENLLQFFCFDEENPVSIFSCLRMARDNAHGVRGKIPGEVWESINAAWIEIRRRRKAGLSSGQAQEFFDWIKERSHQFRGATYGTIMRGDVLWFLRLGTFIERADNTARILTVKYQVIREDEDSVREFYRWNALLRSVGAYEAHQTLYKTLSHASIAELLILRNEVPRSLRACLDEMELILAQIEGNAGQTPRRLTTILNAHLTYGTIDDVFALGMQAYLSNFLGDIGAIGQSIHAAYLEVL
>NZ_CP007567.1|WP_005327427.1|1223136_1223937_-|transglutaminase-family-protein
MRLIIDHQTRYHYADVVRRSTQYLRLTPHSTARQQILSWQLELPGEATCTTDGYGNILHVLSLESPHEGILIRAHGEVEICDDAPEDEEHSPISPLSYLRPTPLTSPTPALRDLAKACLPEEPALADLQSLMARILVLMPYQPGSTDATFSADEALASGSGVCQDHTHVFLTCCRHAGLPARYVSGYLYSQDSSHVAMHAWAEVWIEARWHTFDVTNLTCSANEHLKLAVGMDYLDACPVRGVRYGGGCEQLQSQARVTRLDGQQQ
>NZ_CP007567.1|WP_005327426.1|1222418_1223120_-|peptidase
MTYCVAMCLQDGMVFASDSRTNAGVDHIATFRKLHLFNREDRVLVLQSAGNLATTQSVISLLTEGQELLALPSLYEVAALIGQTIRTVISRDGGQQQGHVNFGCNILLGGQIRGERHRLFHIYPEGNFIEASVDTPYFQIGESKYGKPIIDRIIHHETPLQTALQCALISIDSTLRSNLSVGLPLDALVYSEGSFSAAHLHRITEQNPHFLALRKAWGEGLQQLFQGLPTFPL
>NZ_CP007567.1|WP_041205479.1|1221850_1222336_-|YqhA-family-protein
MRRFNVMLNGSRLMMFPFYVCILICVALLMVKFAMQLYVLCRDIIDIHYLDLITGVLTLVDFVLVAQMLILVAICGYVQFIKTPEQRAALGDNWLSKINFASLKLIVINSLVTIAGIEVLKAFLDDGSGNEIEMKWSVIVFLAFSTAALIYAITERLADHK
>NZ_CP007567.1|WP_005327423.1|1221277_1221727_-|hypothetical-protein
MTSLSLSPRQCWQWLAYHHQAAEGSLYLMFFSGLLLWEPLTPVWSLARWNLFLHVMLSLTLFPLLFGAFWLSHRSLLSKSRKPFLRTTGRIIEALLLVCLASGLLLVLHGTPGDSLGNLASWAHWLSALALTPLVLRHAWRWTILTWRT
>NZ_CP007567.1|WP_041205476.1|1218303_1221273_-|hypothetical-protein
MLKLLLSLMFAALLPGTASAQEMGTAMIAYDEDDAPRLLVANQGAGSVTLLERKSGKRLNEVQLGGDLRQLARADDATLLVTDYSGDRLLLLDDNLDLEKAIPTGHRPYGVIFDPKRRWFWVSLFESGRLQAYDSSGKLQLDAETAETPRGLALTDDDHLLLTHAMTGQLAIYDLARLEKGAKGATLPKPSLITLAETHSATPSDSQGLPRLLDGIALSPDGSEAWLPHVLWSFDHSFQFQRTVFPAVSIIDLDEEKERVDERKQLFLQINLPNVGNRSQIVSNPFAARFAADGKRVYLTLAGSEDLLVFDLSRSGKQNSNRHRRKKFQGGAKATQLLRHLPGQNPRDLLIDGDHILVHNVMGQDLTRLNSGGSGPFARVTVDVPHFAKLVETDPRPEPLKRGERLFNLGNTAANSRFPMAGDNWMSCNSCHLDGFNFTNRHLMAAHRQKSGDNAINGHANLANMVAGDFVGEYLRMTQQTQGGMGHDTRDGAAVVDPAKPQPEVQAMMEDLHAFVTADGNLPYLANWLRLDAPRTDPAKAPTTHPKEWLNSASCQNCHQQAFKDWSESNHRLMGNSHPYYKVVQALARETEGEAFGQWCQGCHMPQQVLNGPQDLPKGSHMFEQGGASLIAAHKAGEPVVEEGTGCVLCHRITKLEDTGGNSAFTVNLKDRESYVFEDAPGGSLQHWLAERQINSRPAMHKASYQKDFYRDAALCKSCHNEFAPGTGANIVNTWDEWENSSFAKAEDLAKRRTCIDCHMNPEPGNGGAPVAGQSTENGPVKERLYRHNFTGAQHQLVGLRNPALEQESLALLRASATLSARIDGTVDNRQLVVRVTNVGAGHAFPTGVADFREIWLELTVTDANGNIVLTSGQPVNGAVPEDARLFRKVFGDAEGKPVGLKFWRYAKLLEDTRIPADGWRDEAWPLPADAQGPFKADIRLNFRTYPKWVSDAVRAAEPDLPAPPIVQLNRLQLTLQPLPVTPDTEPQS
>NZ_CP007567.1|WP_005327419.1|1217479_1218304_-|FTR1-family-protein
MFASFLITLREGLEAFLLVGICLSYLAKLGASRYNKLIYLGVGLGLITSLVVAFLFQVVVSQFESERYNHLLMAGILLFATLVLTYMAIWMQKQAKSQVGAMTARIDAAINGGNLFGLVLLAFLAVMREGFETVLFFSALIYSGQGVDLHEGLIGALGGLLVSVALVWGLLRSTRKVALAPFFRWTGLLIIIIAAGLLSSAVNMLQAADVITFWTTPVFNISQVLDDRGVFGTFLRALFGYNASPAGLQLLTWAAYLAIFVTLWHRSYQPRAQG
>NZ_CP007567.1|WP_005327418.1|1215969_1217394_-|NAD(P)/FAD-dependent-oxidoreductase
MSDNNKKSIAVLGAGPAGLMAAWRLRRAGFAVTLFEQEPVVGGMCATQTFKGRDGEYRFDYGGHRFITKNPELLAFIDELMGDDLLHAERKSVIRFGGRTYDYPLNLTNLLKTAPLPLMAGAVKDLLLLPFAKKPDDFAKASFAEWIQSHFGRTLYRQFFEGYTGKLWGINPDKLSADWAGQRISLIDLKDVARRLLPRRSGNLSVRTYARKYRYPKYGFGQIFTTLGERLVAEGALLKTGATITRLEQADGRIERVYWQQDGIEQSEHFDQVISTLPLPLTCQHLGLPCDLHYRSLRFVNMPLKQENLSDNTWQYLSDPHILATRLQEPRRRSPFMAPQGQTSVMLEIPCNPGDATWQAPLADLRGRVTADLASLGVDTAQLGDETFEARSEYAYPLMDLGYQARRNEAIKALMPINNLIMTGRQGTFRYIFTDTAMEMGMMAADMVIDGVDRRHAIFNHRNENTVIETQSVA
>NZ_CP007567.1|WP_005327417.1|1215268_1215829_-|hypothetical-protein
MTIRPGLLALTLLLTLSGQAQAYSYAAAGKEPLIDVREALLGAATNGKDASATLSEIADELAYLEQHHKVELQAPLAAAIKAKDAAATAALLNRAYKAEIERRLEGASQNLGDYQTAKVLVVKSKRFLDLILPSLSEGDRKAADQALARVLDAIGNPGVFGVGAKPADAAAFAEAEKTLMAVLAPL
>NZ_CP007567.1|WP_010674210.1|1227204_1228818_-|IS1634-like-element-ISAs25-family-transposase
MAAPAISIRNLDHLGLVAALCQELGIARMIDALLPKTPPFKVSHGEALVAMIVNGLGFHSSTLHMFPQFFANKPVERLIGPGICADDLNDDVLGRCLDALFEADVSALYQVMAAQVVERLGLKSTAVHLDITSFHVDGAYDCADGDLVGKLQLVRGYSRDHRPELNQVILELICENQAGLPVYMQALSGNSNDTKAFAQTVRRHLSSLKAAQECRYLVGDAALYCADTLQLLAQQQQLFVTRVPVTLNEAKQAVATIGAQPLTALGNGYHGRWQHANYAGVAQRWLLVRSEQASHREQQTLAKNLLKDSTRELKAFAKLCARRFACEADAQAELSCFTASLMLLQLDAEVVGEPVYTGRGRPKRGEEPIGHQFQITGLAATSLACVEEARNQTGVFILATNDHSDTLTMAELLATYKAQQNVERGFRFLKSPEFLTSSLYLKKPERIEALLMVMTCSLMIYAALEHRIRQGLVEQNRSVADMKKKPTQQPTARWIFLRFGGIHEYRLGEAPPQVTELTGDQQIILEVLGERYRQIYS
>NZ_CP007567.1|WP_049832156.1|1229021_1229855_-|hypothetical-protein
MKMLELKHHARQIVSIKTRGQCTAIQGDTPPVLAKAGVKCAGTTEEQNAWIMRLYLDRAPGQKIDASHLISLREQWLTESDLIEIKKRVRLSYEFDHKRQLVNPRMVEVAGEAHIACDTVPWDSAGMADHCRARFDGWREDNCLKTLEDWASWEDYYESALALQGSKMRVREDGSLGILTRILTRSLVQKAWFDHTMTYGEISALLTSVGLPVTVDTCKNSKRAALPENVVPVTGEVLRVLALLLRQVPEYPLEPLFKPERLDEVKSRLNSMEISHA
>NZ_CP007567.1|WP_049832157.1|1229851_1231633_-|hypothetical-protein
MFEFKKAEIGVIEEDQPEPPHLKFAIKKVSFDPKQPPISFADGEDLWIGVDAEWVTRDGQNIVLSYQVYCVNSRDETLGKVIYPELGKRLAFETLISMAVEDCRAAGLIKKWPRKIVVVAHFLRADLSTFKDFWSMKTRLDGQGGSVVGQIITDSGYGVDETAERKRRAPLKPITLRDRNRKLRKSIIQFVDTLFLSPNKSPLSALGSMLGLPKVEIPEGYSIERMDELLVGDKEAFERYALRDAEIAVKYALKVRDFLGGQFGLQKLPRSLGAVGVAVFRQLLKAADVDYMAAFGLVIKKEERWNSGKGKVATKAVKRPSPDRWRCEALAICCYYGGRNESFMIGPTPIGDWYDWDLKGAYTTGLCDLLEPDYANMYTSSDPQDFIGHVMGFAYVEFAFPAGTRFPCLPVRSEQYGLRFPLSGLAYVTAPEIELALSMGATIAIKHGVIVPWVAGSQPLFEDFTRMIQRLRREYPKKSLEEVMVKEIGNSLYGKLAQGLSDKTAFDTATGLSKKIGPSAVTNPYMAAHTTGLIRAVCGELLHRIPSHRTVVSVTTDGFLTDAPLEELDQTGPLCRRYQALCQRLHGDEEVGQ
>NZ_CP007567.1|WP_041205484.1|1231697_1232210_-|hypothetical-protein
MTKNAARNTSTRLVKKTEPACTLTAIIGRNLVNLAHIAYTKRYQPLNESLDRMTPDAISRLGVGINSLERQIAFDAAAEPEKQVQLLKDVRDALANAGLLEKYFMLEDGTIVLPELVKSADYGDMGNGPVVRLYADGIEKPILTCLCSSEAACVQLLTELSNRLNGSSTQ
>NZ_CP007567.1|WP_012564931.1|1232525_1233473_+|IS30-like-element-ISAeca1-family-transposase
MKYQQLTEGLRYQIACLRDHGLSQARIAKQLGVHPSTISRELRRNCAGQAYQPQQAHQLATARRLTSQKRTVPSDTIDFVCMALVADWSPEQISGVGDMINCPVSHEWIYRYVARDKANGGTLYRHLRQGHKRYRKGKNSKRSVIPNPVSIDERPAIVNERSRVGDWEVDTVLGKQGSGAIVSLLERKSRLYLVQYVPSKTASAVADTIISMLKPYQAHVHTITADNGSEFVEHERVAAELEAQVYFAHPYSAWERGQNENSNGLLRQYVPKGSDLSVVTAEALSAVEKRLNFRPRKCLGFKQPQVVFDELLKAA
>NZ_CP007567.1|WP_005327636.1|1234748_1235975_-|site-specific-integrase
MANAPSRFRFTQKSIEALPPNPPNARSTEAEYSDTQIPGFKCLVGKGEGSKKFLLRYLWQGRKRAISIGRFPDVDLNTAREIATDYKRLLSQGIDPKQQKEDKRQELTLTELFEQHYFPYAMHHKRSWRDDAQRFRDHLKPALGSRLLSEIKLEQGQALQTNLLSKVKPATNNRITTLLKAILTWSVRMGYLEQHPMRHLKTLTENNQRTRYLDKGEIRRLFMAADIDENRYAGQYVKLLLLTGLRKDELRLAKWEHLDQSQLTLFIPHTKNGKSRILHLNHMAMQILKETHPIEGNLYLFPGQKQGQPLNNVTRPFNRMLKRARIEGPVCIHTCRHSVAALIVSSGGTLYDVQAQLGHSSSQSSQRYAHLHASRLRHTSAQVANCVEQALLINSAINSEPLGLKRVG
>NZ_CP007567.1|WP_005327660.1|1236281_1236728_-|DUF2787-family-protein
MKPTLVITGLPVRISHDLKKLLEQAISSAQEDSPDEIPDCTTPAALTLNYRDPDYSATTGGYHPVEIRLERWDDGWHLRYVTDFAYVGQGWCTELAKELDFDFSIEEYTHSMMGEISPSEVHEWFDVWQQSFCCYAQMGVFTLTVTPD
>NZ_CP007567.1|WP_005327662.1|1236794_1237280_-|hypothetical-protein
MNTKTNKQGANLQVSTPETSDKPVQPAKVILVSGVATLLSPGSTTTVGYEIGHEPEQAELLIRLTGSSGGGLCSKEWFGLAQVVDLLNEQQPDKAFTSGLFKVIWHFKGSSNNAGFLAAVLRHLDLTKAAPEVRFGHLITGKHSEWFDSLKAKLPEVNTTN
>NZ_CP007567.1|WP_005327664.1|1237299_1237824_-|hypothetical-protein
MDEFIQEGKYASHETLKGYAYSWQTLSLLTQEVIEHGCYVPEFLPEENQPVLLVVVREATVLKAKSLHSEAPEVLIAIASHTGESVRDDDEGYYADYWRLDSGHIQLIDCAEHAVFWLPLPTAETWEPHHFTGYGTPFDALTAPAPVYRHLIFQLKPDQTVPALGSNIYLKSTI
>NZ_CP007567.1|WP_019706001.1|1238073_1239021_-|IS30-like-element-ISAs2-family-transposase
MSYQQLTEGQRYQLSVLRAQGMSILATARAIGVHRSTLYRELRRNAGPQGYQPDNAHQHATHRRASAAKSRLSADVIQFVELTLAWWWSPEQISAVGKQIGLMVSHEWIYRHVAADKARGGQLYRHLRQGHKRYRKGASSLRSPIKEARSIDERPAIVDSRERLGDWEADTVLGKQGTGALVTLVERKSRLYLVKRVASKQAGVVRDAIIEMLTPYIEQVHTITFDNGGEFAEHKAIEEALGAETYFAHPYSSWERGLNENSNGLLRQFIPKGTDLREVTDEDVRRAEQWLNLRPRKCLGFRQPVKVFEEYRQAA

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Crispr_ID: NZ_CP007567_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_4

2436083-2436206

TypeV

Consensus_repeat	Method
CTAGCCAAAGCGCAGGATTACACCAAGCGTTGCCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_4

>merge|NZ_CP007567|4|2436083-2436206|CRISPRCasFinder
CTAGCCAAAGCGCAGGATTACACCAAGCGTTGCCATCGCCTGGCCATCTCCCTCACCCTCCCTCAAAGGGAAATGACGGATTATTGCCCTAGCCAAAGCGCAGGATTACACCAAGCGTTGCCAT

>NZ_CP007567|4|4|2436083-2436206|CRISPRCasFinder
CTAGCCAAAGCGCAGGATTACACCAAGCGTTGCCAT	CGCCTGGCCATCTCCCTCACCCTCCCTCAAAGGGAAATGACGGATTATTGCC
CTAGCCAAAGCGCAGGATTACACCAAGCGTTGCCAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_025201450.1\|2425670_2425973_-\|DUF1232-domain-containing-protein	unknown	unknown	gnl\|CDD\|225876
NZ_CP007567.1\|WP_041206000.1\|2426469_2427675_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271177
NZ_CP007567.1\|WP_041205999.1\|2425965_2426322_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_005331986.1\|2432186_2432936_-\|3-deoxy-manno-octulosonate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|235473
NZ_CP007567.1\|WP_148304701.1\|2439804_2441234_-\|IS66-like-element-ISAeme24-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP007567.1\|WP_041206003.1\|2431331_2431976_-\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|236538
NZ_CP007567.1\|WP_041205080.1\|2441742_2442942_-\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NZ_CP007567.1\|WP_049832193.1\|2451087_2452764_-\|H-NS-histone-family-protein	unknown	unknown	gnl\|CDD\|182858
NZ_CP007567.1\|WP_041206007.1\|2444039_2445146_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|366704
NZ_CP007567.1\|WP_005327996.1\|2446264_2447683_+\|IS66-like-element-ISUnCu16-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP007567.1\|WP_041206008.1\|2445355_2445907_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|182749
NZ_CP007567.1\|WP_005331987.1\|2432932_2433133_-\|Trm112-family-protein	unknown	unknown	gnl\|CDD\|225391
NZ_CP007567.1\|WP_005331991.1\|2434278_2436048_-\|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA	unknown	unknown	gnl\|CDD\|183016
NZ_CP007567.1\|WP_041206006.1\|2443268_2443739_-\|YhcH/YjgK/YiaL-family-protein	unknown	unknown	gnl\|CDD\|377217
NZ_CP007567.1\|WP_005331989.1\|2433283_2434279_-\|tetraacyldisaccharide-4'-kinase	unknown	unknown	gnl\|CDD\|234808
NZ_CP007567.1\|WP_041206001.1\|2428518_2429073_-\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|182763
NZ_CP007567.1\|WP_041201465.1\|2452779_2453943_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|350194
NZ_CP007567.1\|WP_041206002.1\|2429366_2431220_-\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NZ_CP007567.1\|WP_004576012.1\|2449177_2450596_+\|IS66-like-element-ISAs21-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP007567.1\|WP_005331310.1\|2453972_2456957_-\|Hsp70-family-protein	unknown	unknown	gnl\|CDD\|212667

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_025201450.1\|2425670_2425973_-\|DUF1232-domain-containing-protein	gnl\|CDD\|225876	COG3339, COG3339, Uncharacterized conserved protein [Function unknown].	1.90862e-10
NZ_CP007567.1\|WP_041206000.1\|2426469_2427675_-\|site-specific-integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	6.29554e-34
NZ_CP007567.1\|WP_005331986.1\|2432186_2432936_-\|3-deoxy-manno-octulosonate-cytidylyltransferase	gnl\|CDD\|235473	PRK05450, PRK05450, 3-deoxy-manno-octulosonate cytidylyltransferase; Provisional.	2.55943e-155
NZ_CP007567.1\|WP_148304701.1\|2439804_2441234_-\|IS66-like-element-ISAeme24-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	2.03572e-42
NZ_CP007567.1\|WP_041206003.1\|2431331_2431976_-\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	gnl\|CDD\|236538	PRK09483, PRK09483, response regulator; Provisional.	5.13731e-165
NZ_CP007567.1\|WP_041205080.1\|2441742_2442942_-\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NZ_CP007567.1\|WP_049832193.1\|2451087_2452764_-\|H-NS-histone-family-protein	gnl\|CDD\|182858	PRK10947, PRK10947, DNA-binding transcriptional regulator H-NS.	1.83125e-08
NZ_CP007567.1\|WP_041206007.1\|2444039_2445146_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|366704	pfam01553, Acyltransferase, Acyltransferase. This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.	1.43681e-07
NZ_CP007567.1\|WP_005327996.1\|2446264_2447683_+\|IS66-like-element-ISUnCu16-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.91172e-41
NZ_CP007567.1\|WP_041206008.1\|2445355_2445907_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|182749	PRK10809, PRK10809, 30S ribosomal protein S5 alanine N-acetyltransferase.	6.31448e-57
NZ_CP007567.1\|WP_005331987.1\|2432932_2433133_-\|Trm112-family-protein	gnl\|CDD\|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	2.27803e-17
NZ_CP007567.1\|WP_005331991.1\|2434278_2436048_-\|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA	gnl\|CDD\|183016	PRK11176, PRK11176, lipid A ABC transporter ATP-binding protein/permease MsbA.	0
NZ_CP007567.1\|WP_041206006.1\|2443268_2443739_-\|YhcH/YjgK/YiaL-family-protein	gnl\|CDD\|377217	pfam04074, DUF386, Domain of unknown function (DUF386). This family consists of conserved hypothetical proteins, typically about 150 amino acids in length, with no known function.	1.46627e-37
NZ_CP007567.1\|WP_005331989.1\|2433283_2434279_-\|tetraacyldisaccharide-4'-kinase	gnl\|CDD\|234808	PRK00652, lpxK, tetraacyldisaccharide 4'-kinase; Reviewed.	2.0377e-167
NZ_CP007567.1\|WP_041206001.1\|2428518_2429073_-\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl\|CDD\|182763	PRK10832, PRK10832, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.	1.16294e-83
NZ_CP007567.1\|WP_041201465.1\|2452779_2453943_-\|AAA-family-ATPase	gnl\|CDD\|350194	cd18807, SF1_C_UvrD, C-terminal helicase domain of UvrD family helicases. UvrD is a highly conserved helicase involved in mismatch repair, nucleotide excision repair, and recombinational repair. It plays a critical role in maintaining genomic stability and facilitating DNA lesion repair in many prokaryotic species including Helicobacter pylori and Escherichia coli. This family also includes ATP-dependent helicase/nuclease AddA and helicase/nuclease RecBCD subunit RecB, among others. UvrD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.	8.87132e-10
NZ_CP007567.1\|WP_041206002.1\|2429366_2431220_-\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NZ_CP007567.1\|WP_004576012.1\|2449177_2450596_+\|IS66-like-element-ISAs21-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	3.25117e-43
NZ_CP007567.1\|WP_005331310.1\|2453972_2456957_-\|Hsp70-family-protein	gnl\|CDD\|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	4.65178e-41

>NZ_CP007567.1|WP_005331991.1|2434278_2436048_-|lipid-A-ABC-transporter-ATP-binding-protein/permease-MsbA
MQQETSQESWPVFKRLLGYVRDRKLGLVGGIIGMLGYAAVDTTFVYSIKPLIDQGLNGNDSSVLKWMPFFVLGIVALRGCAAFLSNYCMAWVGNHVVMRLQQQVFSHLMAMPMSFFDRQNTGNLLSKVTYDAGQVSSAASSTLVSLVREGATVIGLLGLMFWHSWQLSVIFLVVGPVVGVLIGLISRRFRKISRHIQQAVGDITTSTEQMLKGHKEVLMFGGQQVEDKRFYQVSNRMRQQTMKMVAADAIGSPIVQMVASVALAVFLYVATIDSVKATLTAGTFTVMVTSMMMLLKPLKSLTDVNNQFQRGITACQSLFGLLDSTPEQDTGTRTLERARGEIEFRNVTFTYPTKDTPALHNISFKVEAGKSVALVGRSGSGKSTIASLLTRFYDIEQGEILLDGVNIREYKLSELRKQYALVSQHVHLFNDSVANNIAYAAEEKYSREEIQHAARIAHADEFVRKMPEGYDTVIGENGASLSGGQRQRIAIARALLRDSPVLLLDEATSALDTESERHIQAAIDELCKARTSLVIAHRLSTIEKADEILVIDEGHIVERGNHDALMAQQGTYAQLRAIQFGNVAVSNKG
>NZ_CP007567.1|WP_005331989.1|2433283_2434279_-|tetraacyldisaccharide-4'-kinase
MLERLWYGKSGWRWALAPLALLFALVSGGRRFAYWRGWFSTYRASLPVIVVGNISVGGNGKTPVVVWLVEQLQARGWRPGVVSRGYGGKAPHYPYRLDATSTTAQAGDEPVLIARRCGCPVVVAPRRADAVRLLEQSGEVDIVITDDGLQHYALARDIELVVVDGARRFGNGCLLPMGPLREPMTRLKRVDAIICNGGTPAQGEYPMALVAAAPRRVCDDAPLEAPLTGPVDALAGIGHPPRFFATLTGLGYELAERVGYADHQAFDRDELLARFGQRPLLMTEKDAVKCRAFAPPHWWYLPVSAELPAALLDTLLQRLTPLQAPGPDHAH
>NZ_CP007567.1|WP_005331987.1|2432932_2433133_-|Trm112-family-protein
MALDIKLLDIIACPVCKGKLHYQPQSDKAAHELICRFDRLAYPLEEGIPVLLENRARHLPLEELKP
>NZ_CP007567.1|WP_005331986.1|2432186_2432936_-|3-deoxy-manno-octulosonate-cytidylyltransferase
MSFVVVIPARYASTRLPGKPLADIHGKPMVQHVVEKALQSGADRVIVATDDELVRQALRATGVEVCMTSPDHQSGTERLAEVCRHYGFAADTIIVNVQGDEPLIPPVIIRQVADNLAAATAPMATLSVPIKDAEEAFNPNAVKVVTDKDGYALYFSRASIPWDRDRFAKSHEQIGNHYQRHIGIYAYRAGFIQRYVDWAPSALEQVEALEQLRVLWYGEKIHVAQALEAPPVGVDTQTDLDKVRALLAN
>NZ_CP007567.1|WP_041206003.1|2431331_2431976_-|UvrY/SirA/GacA-family-response-regulator-transcription-factor
MINVFLVDDHELVRTGIRRILEDVRGIKVVGEAQSGETAVAFCRQHHPDVILMDMNMPGIGGLEATRKILRIRPDVRIIVLTIHSENPFPTKVMQAGAAGYLTKGAAPDEMIHAIRLVHSGQRYISPEIAQQMALSQFASADENPFKSLSERELQIMMMITKGQKVTDISEQLNLSPKTVNSYRYRLFSKLNINGDVELTHLAIRYGMLDADTL
>NZ_CP007567.1|WP_041206002.1|2429366_2431220_-|excinuclease-ABC-subunit-UvrC
MTFSSEPHFDSKAFLSAVTHQSGVYRMYDGGGTVIYVGKAKDLKKRLASYFRPNVDSIKTRTLVRQIADIQVTVTHTETEALILEHNLIKQYQPRYNVLLRDDKSYPWIIITAHQHPRIGVHRGARKIKGEYFGPYPSGGAVRESLHLMQKIFPVRQCEDAVYANRSRPCLLYQLKRCAGPCVAGLVSEAEYAQQVELAKLFLAGKNQQVIGELVGKMESASGDLRFEEAARYRDQIQALRRVTEQQSVSGNVLDELDVVGVAFEQGTACIHVLFIRQGKVLGSRSYFPKVPADTPLDEVVQSFLLQFYLSGQGGRQIPSEVLLDVALEDESVIAQTLSQTAGYKVRVQSRTRAERARFIKLASINAQTALRSRLAHKSTITARYDQLEELLELERPIARMECFDISHTMGERTVASCVVFNREGPLSSEYRRFNIDGITGGDDYAAMEQVLERRFGKQQEPDKVPDVLFIDGGLGQLRRAEEILARQLEFLGGKYPLLVGIAKGVTRKAGLETLILGESHEELHLPADMPALHLIQHIRDESHRFAITGHRARRAKARTTSTLEDIPGVGPKRRQALLKYLGGLQEVKKAGVDELAKVPGISQELAQSIHDALHSL
>NZ_CP007567.1|WP_041206001.1|2428518_2429073_-|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MTNIPNLLTFFRILLIPVFVILFYLPYQWSYLAAALVFILAAATDWFDGYLARKLNQSTAFGAFLDPVADKIMVAAALVVIVEHYNTIWVTIPAMTMIGREIIISALREWMAELGKRSSVAVSWIGKWKTMIQMVSLTGLIWQYDIWMVWLSYVLLYVATVLTFWSMFQYMKAAWGDLTYHSRF
>NZ_CP007567.1|WP_041206000.1|2426469_2427675_-|site-specific-integrase
MQTKFRFTNAAIKALPAQQRDAGATELEFSDTEVIGLKLLSGKSQGSKRFLLRYTLQGKKRSIALGRFGDIDVSQARTIARKYKAMLAEGIDPVAERDSYKTEPTLSEFFWQTFLPHLKTIGKRSINSDIQRFKHNIEPRFGAMRYRQLKAMDVLQLQSEMVHPNNPQQTAYAPSTANRVLAQLKTMGSYAVRWGILDTNEAAKIKLLKEDNARTRFLSIEEMKRVIEVALQDRNQAAGSFIAMLYLTGARKSEVLLAKWEHVNWEDKTLFVPLTKNGKSRIIYLSALAIDILEKLPRIAGNPYVFASQHIRCQGKPIGEPRCAYERVLQKAGIEDRDEICFHTARHSVASALVSSGQYSLYDVKAQLAHASIQSSQRYAKLTSERSRNISEGLSSMIQAE
>NZ_CP007567.1|WP_041205999.1|2425965_2426322_-|hypothetical-protein
MEWPEESLLAAYPALHVSVMAQIIEPFSSVEEARAFWDATGCSLVIIEMTDSMSEFQAMPQHTQNQVMFGLRYPEQEFAISEDWRLLLAILNDEGAGIYLLIRSDAPLITTLEGMHHE
>NZ_CP007567.1|WP_025201450.1|2425670_2425973_-|DUF1232-domain-containing-protein
MSNPSHSDIMRKLKEIKGIKELLEKAVLLYVLLTDGDLPVWCYALIIGALAYLVNPFDVVPDPIPFAGYLDDLSVITSALAALPVKSHHRQSAKDRMRSL
>NZ_CP007567.1|WP_148304701.1|2439804_2441234_-|IS66-like-element-ISAeme24-family-transposase
MNKKKLFENAAPQAHDLHDANRIIQELWNKLREYEDLLALSSRNSSKSPSSDSPAAKAERKKFTTPRGRNQVGAQPGHTGHRRELSELQSTDLVVACKPASCCAECGGEVVANAAPSFRHQVFELPTLPLEITEYQLFHGHCRHCDALSKGELPKAAPSGQMGPRLLSYIAVLVGQYHLSVRKIQSLLRDQYGMTFSVGAISEAQGRISSMLTPIHQALKQHIQKAPIIHADETTHQRNGESNTRWLWLMATTDAVFQNIRYFRSQDNAKHLLGAVTHGVVVTDQCASYHWLDPTRHQFCLAHVQRNLQEMADYGGGGQTAYLGRRLVVLFKTVFRTQHRYESGLIGEQVWLRRMHRLRRSIQVVLTQGAETPARRYAGRCQHILKYETGLWVFLQYPGTPLTNNEAERCIRGSVILRKICFGTSSDRGDKFRSRVLSVIETCKKRSQSAIEVLCRIVTAVMTGQPYPDVFNLTSA
>NZ_CP007567.1|WP_041205080.1|2441742_2442942_-|acetate-kinase
MSKLVLILNCGSSSLKFAVMDAETGEDMLSGLAECFNLDDARIKWKLHGVKGEAMLGAGAAHQEALDHIVGHILPQDPTLAEQLVAIGHRIVHGGEQFSRSVRIDDGVIAGIEAAIPFAPLHNPAHLIGIRAALKVFPALAEKNVAVFDTAFHQTLPQEAYLYALPYKLYQENGIRRYGAHGTSHRFIAEETAKALGKPLSELNIINCHLGNGASVCAIRNGESVDTSMGLTPLEGLAMGTRSGDIDPAVVFFMHDQLGYSVDEINQVLTRESGLLGMTEASSDCRYVTTNYATDAGAKRALDVFTYRVAKYVGAYAAAMDGRLDALVFTGGIGENAAMVREMVLARLALFGFKVDKEANNAAVLGGEGPITAEGSRLALVMPTNEELVIARDALSLVG
>NZ_CP007567.1|WP_041206006.1|2443268_2443739_-|YhcH/YjgK/YiaL-family-protein
MITGSLDTLQRTPLPAPLARIMAEVVKSLAHWSEAQLGKHDIDGLKLFCLVSEALTEPVADRRGEFHEQYLDIQLLLRGEEWIGVGPHAYVNDGADHPHPDLWFVDDDQTSYLALQPGDFAIFWPGELHRPLCTLTTPGLVKKLVVKVHQSLLATV
>NZ_CP007567.1|WP_041206007.1|2444039_2445146_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MTEVDRFADIRPYRDDEVPAAIERLIQDDEFIGAIAKYRFGSLMSWLGWAIRPLIRQFLRHKWAKVSTIHQVQMGVTRYMSRMIATSTQGVSFSGLEHLKKEQGYLFVSNHRDIAMDPAFVNWGLHTHGFDTVRIAIGDNLLRKPCATELMKLNKSFIVKRSAKGPREMMKALGELSAYIGQSVHEGHSIWIAQKEGRAKNGDDKTDPAILKMFYVDGKKQKIDFVDYMRSLNIVPVSISYEVDPTDKAKARELYEKSVNGSYEKGEFEDIESIVAGIIGQKGRVHVSFGAPITEGFSDPDELAALIDKAIWSSYRLFPGNYLAADVPGKASTIEQTAFLTRQSEVPEEHKAIWRAMYAKPVENARKA
>NZ_CP007567.1|WP_041206008.1|2445355_2445907_-|GNAT-family-N-acetyltransferase
MTLPHITTARTRLTVLPPERACLMLDFYQRNRVHLAPWELRRDESFYTLGHWQGRLRDGYGQFFDGSAVPLVALDPKGERVLATCHFTHIMMGMFKACHLGYAIDQAYEGQGLMQEVVAAGIDYLFRERGLHRIMASYMPANRRSGALLARLGFEQEGYARDYLMINGRWEDHILTALLNPAG
>NZ_CP007567.1|WP_005327996.1|2446264_2447683_+|IS66-like-element-ISUnCu16-family-transposase
MSTSMTPPAASPLTLEQANELIQKLMARIAELEDRLNQHSGNSSKPPSSDGPGSPPPARPRLASGKKRGAQPGHKGARRERHPADERLTVIPHYPARQCACCGGNVVFHDKPYRVHQVFDLPEVSYRVTEHQLFSGTCCHCIETSPAPLPETVSSSQMGTNLLSYIALQSGLFHQSISQIQQQLKQHFGLSFSRGAISEAQGRVSAMLTPTHQAIKQQVQSASCIHADETRHQRGGERRWMWLALSKVAVCFMTAFGRGQDAAKRLLGSELDGVLVTDQYAGYRFIDSSQRQLCWAHVLRNVAAIADSGEKVNQPIGARLVLLANSVFRVRHGYEQGVLSQKQYQRRLERCRQSWRKELGRGSLLCSKRYRGRCRLLLKDDEMLWRFLENDEIALTNNEAERALRGYVLWRKGSYGVWSHRGELFRQRILSLIETAKRLGRCPQEWLRAVVSACIEKTDYPLPEELLSTSSR
>NZ_CP007567.1|WP_004576012.1|2449177_2450596_+|IS66-like-element-ISAs21-family-transposase
MSKPITPPPGLPLTLEQANELIYKLMARIAELEDRLNQNSNNSSKPPSTDGSGTPPARKRPASGKARGAQPGHKGQRRERHPEDDRLTAIPHYPARQCACCGEQVVSHDKPYRVHQVFDLPEVSYVVTEHQLYRGTCRGCVTTSEAALPDTVSHSQMGANLLSYIALQSGQFHQSISKIQQQLKQHFGLSFSRGAISEAQGRVSAMLTPTHQAIKQQVQSAAIIHADETRHQRGGERRWMWLALSKVAVCFMTAFGRGQEAAKRLLGSELDGVLVTDQYAGYRFIDSAQRQLCWAHVLRNVAAIAESSDAVNQPIGARLVLLADTVFRTRHGYEQGCLSREQYQRRLQRCRQSWRRQLERGSVLCSKRYRGRCQLLLKDDEMLWRFMENDEIALTNNEAERALRGYVLWRKGSYGVWSHRGEQFRQRILSLVETAKRLGRCPQEWLRAVVRSCIEKTDYPFPEELVLSTPSR
>NZ_CP007567.1|WP_049832193.1|2451087_2452764_-|H-NS-histone-family-protein
MSKYFIGISISELQHWFADNELPLLTDRVTYYKNCPDDSIPSDFDPGSIFNSLPAFSLDDPAGVLIVEISGPRTWEADDDPNIRYLTMSGVKQFIPLTEDARVALSIQWSDVIKLSEAIFEHEFTRFRINKKSISACKAGNLFANIFIDHKQSKFAASRLFTDSLPRALMAAEHKKQDEIGKTFDRQVETWVERAFGDIRKYDKGNKLLDIKDKADSLKSIAVVGLMLRNVEVEAVRVLTERLGKRWKILETKANDDTKSLAPVYSDEIFSRLDINFNINQNGNESINLVTLALFLRWKMAFHNQRSKVDMLSILDDVKSLTGIVDVKLVSNALWMMGAYLGMENIAHTHHHLNKEKYPTLKFAHSVESLVPVQSWQLTENKYLTEDDFPADRRSVTSEHNQQDQQDQQDQQDQQDQQDQQDQQDQQVYQTDNTTSESLEQTKETESALSVTEIGIPMDTDTAIACSNQGIVDMQQRDLDLSPDAGFDSSELGQGVPENKVARKVAKRESSPPMYRYKLKNGNERTWDGEGSIPKALEKQLEQGRKIEEFLINVEGAG
>NZ_CP007567.1|WP_041201465.1|2452779_2453943_-|AAA-family-ATPase
MEWMVPLRRLDEAQQNVLRQCANVTEQPMWVEGFAGSGKTVLLVHAIQTYVQKHPDSNVCVIVFTHALIDLIESGIAPELRSKIPVMTYLNFVNKDKNHYNLVVIDEVQDVPANILNAIRSRADKLLVGGDDAQSIYESGSRAEKIESVLQPDRIKLPMVYRLTRKIINVVKNILPNNNIVTATSARMEDVQVTLAHADSSDAELAWVWHQAIRHAEPGHPSVIVLTDHSAIQDFMRFVAKQNGYPAPKFPTDSWNRYDYSAANQSFLEVGAQGCLQYLGNGHGSLDNSDSRSIVYVMTYHSIKGLDFRTVFLPLLTSDLTFWKGAERADIDRRLFFVGATRSRRDLFMSYHGEKPHPYVQDMPEEELHKIEIGKNPHIRDEDDFIF
>NZ_CP007567.1|WP_005331310.1|2453972_2456957_-|Hsp70-family-protein
MLTIQECLSRSTLCVLSFLEQHLPAIGGELWWQKSVINKLSEQQTKLAEQKQFSALSDFDLAALLNLLERNWRVITDSTSGFDYRRGLNLIIELKNIRNHYAHEPSSGTELDQQMRDVDSITRLLKILGADSALVGQIEALHRDLMMRMLGRETGQIATGEQNTSDQDESGDEDESELSTLEQDMDDPQKGVPVHWLKAGTILEQGVLKKMRSATYVGIDFGTSTSVASIAAVGEDGQGLHTTAIEIRQLDELGREIHSHLVNTCLAWFNQKLLFGVGAARLKQELVSNQTIWTSFKMGLGVDLGPEYNRTALPAGRFEYSIEKPQQAAAVFLKLLYDGIKEYVSKHNLPEQIYYTVTVPASFEANQRQDLFAALKFAGIPESEIRLMDEPNAAFLSYLIDMESRSSEGRFVDVLQTKKHNLIVFDFGAGTCDISVLEVSVSRESILSRNLGISKFWALGGDDIDKAIAEQILLPQLCGGKNMAKFLFTSTQLEEQVLPHLKSIAEALKIACCELAEQRGWKTIEDLKNADSRVTGKPGVPFNIAGKQWQIVEPQISLDEFAEVMALFVGQPCSLESGNKIIDVLQPIDNALEKIELTKDDINMVLFIGGSCENPLIRHYVSKHLGRYVECITPRDLRAHVSQGAALYTLFLRGADIDPIKPITSETIYVLTKGERLQPVVKASSLVPSEGQLQEELIVTRDNQKTIDLPFFSGSMNKPIGHMQLKVPRGSSGFQRGEHVKIEWSISKEKILRVIAEASSIRQVAEFQNPLANEEITEQALSMLKAKQAFNKSVLDGNGRPTDNAALAYSRAAKLAGNWRLAAEMLEAVERLSPGTDHSTNICHFYYMDGDNKNALKWSKIAYERKPSAVTSYNYAVVNNLKNRDTSAYEQLMQECLEHDSNYTSALEGYGRYLMDQGDPEGVELLQRAFNIFKTELDNEELDHSDIQRFKRVANALGKTEIIPSIDKFNRNITPIKTSRGFNHENLVDLATSW

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Crispr_ID: NZ_CP007567_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_5

2506924-2507046

Orphan

Consensus_repeat	Method
TTACAGCACCTTGGCGATGGCATCGCACAGGGGATCTAT	CRISPRCasFinder

1 spacers

DinG

The CRISPR arrays of NZ_CP007567_5

>merge|NZ_CP007567|5|2506924-2507046|CRISPRCasFinder
TTACAGCACCTTGGCGATGGCATCGCACAGGGGATCTATTGATATGGACGCGGGTGATTCCCGCATAGAACCTCTTCGCCTCAGTTACAGCACCTTGGCGATGGCGTCGCACAGGGGATCTAT

>NZ_CP007567|5|5|2506924-2507046|CRISPRCasFinder
TTACAGCACCTTGGCGATGGCATCGCACAGGGGATCTAT	TGATATGGACGCGGGTGATTCCCGCATAGAACCTCTTCGCCTCAG
TTACAGCACCTTGGCGATGGCGTCGCACAGGGGATCTAT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_088813959.1\|2500420_2501982_+\|IS3-like-element-ISAs20-family-transposase	unknown	unknown	gnl\|CDD\|366234
NZ_CP007567.1\|WP_004576012.1\|2498880_2500299_+\|IS66-like-element-ISAs21-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP007567.1\|WP_005329090.1\|2513127_2513787_+\|DUF2057-domain-containing-protein	unknown	unknown	gnl\|CDD\|378258
NZ_CP007567.1\|WP_005329096.1\|2508343_2509285_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|180519
NZ_CP007567.1\|WP_005331306.1\|2503282_2503777_+\|DUF2062-domain-containing-protein	unknown	unknown	gnl\|CDD\|378263
NZ_CP007567.1\|WP_041206030.1\|2514916_2516065_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|179614
NZ_CP007567.1\|WP_041206033.1\|2520416_2521100_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_005331305.1\|2503903_2505409_+\|DUF853-family-protein	unknown	unknown	gnl\|CDD\|283518
NZ_CP007567.1\|WP_041206032.1\|2517583_2518975_+\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|224699
NZ_CP007567.1\|WP_081805720.1\|2497394_2497637_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|183047
NZ_CP007567.1\|WP_041206031.1\|2516306_2517257_-\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|236570
NZ_CP007567.1\|WP_041206028.1\|2497064_2497361_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_041205051.1\|2505457_2506795_-\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP007567.1\|WP_081805894.1\|2501911_2502742_-\|ComEC/Rec2-family-competence-protein	unknown	unknown	gnl\|CDD\|236924
NZ_CP007567.1\|WP_005329092.1\|2510910_2512983_+\|ATP-dependent-DNA-helicase-DinG	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|236966
NZ_CP007567.1\|WP_005331307.1\|2502770_2503289_+\|DUF2062-domain-containing-protein	unknown	unknown	gnl\|CDD\|378263
NZ_CP007567.1\|WP_005329077.1\|2518998_2520366_+\|alkaline-phosphatase	unknown	unknown	gnl\|CDD\|224699
NZ_CP007567.1\|WP_005329089.1\|2513860_2514757_+\|histone-deacetylase	unknown	unknown	gnl\|CDD\|212519
NZ_CP007567.1\|WP_005329094.1\|2509487_2510525_-\|porin	unknown	unknown	gnl\|CDD\|225744
NZ_CP007567.1\|WP_041206027.1\|2496699_2496984_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|224937

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_088813959.1\|2500420_2501982_+\|IS3-like-element-ISAs20-family-transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	4.85301e-23
NZ_CP007567.1\|WP_004576012.1\|2498880_2500299_+\|IS66-like-element-ISAs21-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	3.25117e-43
NZ_CP007567.1\|WP_005329090.1\|2513127_2513787_+\|DUF2057-domain-containing-protein	gnl\|CDD\|378258	pfam09829, DUF2057, Uncharacterized protein conserved in bacteria (DUF2057). This domain, found in various prokaryotic proteins, has no known function.	5.44983e-50
NZ_CP007567.1\|WP_005329096.1\|2508343_2509285_-\|hypothetical-protein	gnl\|CDD\|180519	PRK06298, PRK06298, type III secretion system protein; Validated.	0.00390254
NZ_CP007567.1\|WP_005331306.1\|2503282_2503777_+\|DUF2062-domain-containing-protein	gnl\|CDD\|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	1.09585e-27
NZ_CP007567.1\|WP_041206030.1\|2514916_2516065_-\|MFS-transporter	gnl\|CDD\|179614	PRK03633, PRK03633, putative MFS family transporter protein; Provisional.	0
NZ_CP007567.1\|WP_005331305.1\|2503903_2505409_+\|DUF853-family-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NZ_CP007567.1\|WP_041206032.1\|2517583_2518975_+\|alkaline-phosphatase	gnl\|CDD\|224699	COG1785, PhoA, Alkaline phosphatase [Inorganic ion transport and metabolism].	1.9645e-132
NZ_CP007567.1\|WP_081805720.1\|2497394_2497637_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|183047	PRK11235, PRK11235, type II toxin-antitoxin system RelB/DinJ family antitoxin.	3.20987e-35
NZ_CP007567.1\|WP_041206031.1\|2516306_2517257_-\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|236570	PRK09563, rbgA, GTPase YlqF; Reviewed.	5.29535e-151
NZ_CP007567.1\|WP_041205051.1\|2505457_2506795_-\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	1.77276e-31
NZ_CP007567.1\|WP_081805894.1\|2501911_2502742_-\|ComEC/Rec2-family-competence-protein	gnl\|CDD\|236924	PRK11539, PRK11539, ComEC family competence protein; Provisional.	5.64606e-17
NZ_CP007567.1\|WP_005329092.1\|2510910_2512983_+\|ATP-dependent-DNA-helicase-DinG	gnl\|CDD\|236966	PRK11747, dinG, ATP-dependent DNA helicase DinG; Provisional.	0
NZ_CP007567.1\|WP_005331307.1\|2502770_2503289_+\|DUF2062-domain-containing-protein	gnl\|CDD\|378263	pfam09835, DUF2062, Uncharacterized protein conserved in bacteria (DUF2062). This domain, found in various prokaryotic proteins, has no known function.	3.2069e-47
NZ_CP007567.1\|WP_005329077.1\|2518998_2520366_+\|alkaline-phosphatase	gnl\|CDD\|224699	COG1785, PhoA, Alkaline phosphatase [Inorganic ion transport and metabolism].	8.72955e-119
NZ_CP007567.1\|WP_005329089.1\|2513860_2514757_+\|histone-deacetylase	gnl\|CDD\|212519	cd09993, HDAC_classIV, Histone deacetylase class IV also known as histone deacetylase 11. Class IV histone deacetylases (HDAC11; EC 3.5.1.98) are predicted Zn-dependent enzymes. This class includes animal HDAC11, plant HDA2 and related bacterial deacetylases. Enzymes in this subfamily participate in regulation of a number of different processes through protein modification (deacetylation). They catalyze hydrolysis of N(6)-acetyl-lysine of histones (or other proteins) to yield a deacetylated proteins. Histone deacetylases often act as members of large multi-protein complexes such as mSin3A or SMRT/N-CoR. Human HDAC11 does not associate with them but can interact with HDAC6 in vivo. It has been suggested that HDAC11 and HDAC6 may use non-histone proteins as their substrates and play a role other than to directly modulate chromatin structure. In normal tissues, expression of HDAC11 is limited to kidney, heart, brain, skeletal muscle and testis, suggesting that its function might be tissue-specific. In mammals, HDAC11 proteins are known to be involved in progression of various tumors. HDAC11 plays an essential role in regulating OX40 ligand (OX40L) expression in Hodgkin lymphoma (HL); selective inhibition of HDAC11 expression significantly up-regulates OX40L and induces apoptosis in HL cell lines. Thus, inhibition of HDAC11 could be a therapeutic drug option for antitumor immune response in HL patients.	8.7861e-136
NZ_CP007567.1\|WP_005329094.1\|2509487_2510525_-\|porin	gnl\|CDD\|225744	COG3203, OmpC, Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane].	1.12867e-40
NZ_CP007567.1\|WP_041206027.1\|2496699_2496984_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|224937	COG2026, RelE, Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning].	6.26573e-14

>NZ_CP007567.1|WP_041205051.1|2505457_2506795_-|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNGPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIEKRPRPSRPRAVKISKTRFPVNRNAAPLK
>NZ_CP007567.1|WP_005331305.1|2503903_2505409_+|DUF853-family-protein
MAQPLTLAYANGQPISLLPAMANRHGLITGATGTGKTVTLQVLAEGFSRLGVPVFLADVKGDLSGLGAGGTPSAKLDARLAQLGIPAPAFAASPTLFWDLFAEQGHPVRATISDMGPLLLARLLGLNDTQSGVLELVFKVADDEGLLLLDLKDLRAMVQFAGDNAKSLTTRYGNVSTASIGAILRNLLTLESAGGDHFFGEPMLDIQDLLQTDGAGHGHINVLAAGKLTQSSRLYACFLLWLLSELFEQLPEVGDPDKPMLVFFFDEAHLLFNDAPKALLEKIELVVRLIRSKGVGVYFVTQSPADIPDSVLGQLGNRVQHALRAFTPSDQKAVRIAANTLRANPAFDAAGVITELGLGEALVSLLDEKGRPCVVERAFIAPPASRIGPLNDAERQALIQGSVLHGRYETREDRESAFERLNGGAPTASADVPQTPSEQGGGLLDALNGILFGRTGPRGGQHDGVVQTAAKSVARTLGNEVGRQLVRGVLGSLLGGSKRRR
>NZ_CP007567.1|WP_005331306.1|2503282_2503777_+|DUF2062-domain-containing-protein
MLSRWLVRIKINPDTLRQQKWFALFGERLLTPALWQGGTRALSGAVAAGLFASWIPVPMHSLVAVGLALAFSLNLPLALLAVWFNNPLTLPFMYLYAYRTGCLVLHQTPEPFHLTWSLHWLEHEAATLVPPFLLGSLLLAVLTATTGAMLTLLMLQLGRLSHSR
>NZ_CP007567.1|WP_005331307.1|2502770_2503289_+|DUF2062-domain-containing-protein
MPKRLIKRWLPDQDKLKEHKHLRLFGKLLLDANLWHLNRRSAAGAFAVGLFMAWIPLPCQMLLAAGGAILFRVNLPLSVALVWLSNPVTMPPLFYGAYLVGCQLLGHPAQHIDIQFTWAWLVSVFETLAPPLLLGSLVLALLSSLLGYTLIRTFWRINTVRQWQKRKGARAC
>NZ_CP007567.1|WP_081805894.1|2501911_2502742_-|ComEC/Rec2-family-competence-protein
MDLRLLSFALGASSSLLWPWLPSTAWGGALLAFAILLAHGRHWRLLFLVLGVLWMQLNLQYRLTWLDKLETQTSHIITARVQSTEPSGDKPRDKFARLLLRVETLDEQPLGVAPLVRINAYQALPYLPAGSRITLVSSLKPAHGLANEAGMDGRRLLLGKGITATGNLRRLIEVQASTPGMRERWLAAASIAWQGLEQAPLLEALSFGEQGGITDAQWDLFRGSGLTHIIAISGQHIALVAAAFFKIVVAQSCFKQPLFAPARVSRAAPDLASRHR
>NZ_CP007567.1|WP_088813959.1|2500420_2501982_+|IS3-like-element-ISAs20-family-transposase
MARYSSERKAALLKKLLPPINMSVAELARQENISEVTLYNWRKHAKDGGSPVPGDNKLTDEWPAEAKFAVVLETAALSEIELSEYCRRKGLYPEQVQQWRQACILGQQSARTLQQAEKAQAKADKKRIRQLEQELRRKDKALAEAAALLILQKKPRCLLEQRRRGQLTSLPERQQYVAWWREALEAGARKHPAAEVLGLSLRTLQRWLAGPELSADRRPDAVRSIPAHALSPEERQAVLDVCNSQEFASLPPSQIVPRLADQGRYLASESSFYRILRAADQQHRRGRSQPPRHVPVPTSHTATGPNQVWSWDITYLPSLVRGQYYYLYLIEDIYSRKGVGWEVHEQECGERAAALLQRSIIREQCWKQPLVLHSDNGAPMKSVTLLTKMHDLGVTPSRGRPRVSNDNPYSESLFRTLKYCPQWPSDGFASLEAAREWVRDFMAWYNEEHRHSRIRFVTPNERHRGDDKALLAKRDAVYQAARAQHPARWSGKTRDWTPIGAVMLNPERPEKPEPEQKEAA
>NZ_CP007567.1|WP_004576012.1|2498880_2500299_+|IS66-like-element-ISAs21-family-transposase
MSKPITPPPGLPLTLEQANELIYKLMARIAELEDRLNQNSNNSSKPPSTDGSGTPPARKRPASGKARGAQPGHKGQRRERHPEDDRLTAIPHYPARQCACCGEQVVSHDKPYRVHQVFDLPEVSYVVTEHQLYRGTCRGCVTTSEAALPDTVSHSQMGANLLSYIALQSGQFHQSISKIQQQLKQHFGLSFSRGAISEAQGRVSAMLTPTHQAIKQQVQSAAIIHADETRHQRGGERRWMWLALSKVAVCFMTAFGRGQEAAKRLLGSELDGVLVTDQYAGYRFIDSAQRQLCWAHVLRNVAAIAESSDAVNQPIGARLVLLADTVFRTRHGYEQGCLSREQYQRRLQRCRQSWRRQLERGSVLCSKRYRGRCQLLLKDDEMLWRFMENDEIALTNNEAERALRGYVLWRKGSYGVWSHRGEQFRQRILSLVETAKRLGRCPQEWLRAVVRSCIEKTDYPFPEELVLSTPSR
>NZ_CP007567.1|WP_081805720.1|2497394_2497637_-|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MGSITIRINNELKEKSYAVLERLGVTPSEFIRQALEYVAEQQRSPFKIVVLTDEDEELLAIVRERLAKPSPKIRISLDDL
>NZ_CP007567.1|WP_041206028.1|2497064_2497361_+|hypothetical-protein
MNNADLNPCIKANKHKIEKTPITWVLQYLAILAPMKIEFFSNAAMITRHADRAFFFRFNAESKAESKPHDSKASKALSKDSLILSSAISKELLLYLIG
>NZ_CP007567.1|WP_041206027.1|2496699_2496984_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MDYVLSFDERALKEFQSLDGSVREQFKKKLKNILVNPIVDAKKLRSLKDCYKIKLQSSGYRLVYQVDEEAKEVCVVAVGKREKQAAYTSAQRRL
>NZ_CP007567.1|WP_005329096.1|2508343_2509285_-|hypothetical-protein
MIDFSHPEWRALAQQLLGHSPVVIRGRQWQPLVGLLKDNQLLLAHGSNSYELTPAGRRYLTRELMLAEIATAPPEPEEWLHAQGWQLGEQVNERVLAALYRKSDVNFTPNEQIDFEDKGIRLCADQLLRLRSAQPFSLFFSSGTLIDAAPWLQALGEVTLPERTLADLGKILWGEGNIERVITTDSVGAFAELLLESGCLLVWAPPSASLALQQVVAALPPNVLWSHLTALDPAGVDRVQALAQRLGRPASWWLPRDLAPIKEAYAAPLQDARPWEPSRIPRPLRAWCSDLVESNRGLSAEVCALASGWHAIG
>NZ_CP007567.1|WP_005329094.1|2509487_2510525_-|porin
MKKTILAIAIPALFASAANAAVVYDKDGTSFDIYGRVQANYYGEHDDTDAELVGSSRLGWSGKVALNNTWSGIAKTEWQVSAENSANKFDSRHIYVGFDGTQYGKIIFGQTDTAFYDVLEPTDIFNEWGDVGNFYDGRQEGQIIYSNTFGGFKGKLSYQTNDDKAVKVTDIGQGIKEDAIYGPNAKRNYGYAAAAGYDFDFGLGLNAGYAYSDLESTASSASGDKKEWALGAHYAINGFYFAGMYTQGDLSYDNTTQGSNKDKGRGYELAASYNVDAWTFLAGYNFAEGKVLSNSSGSSYEDIVDETLLGVQYNFTSKFKAYTEYKIQGINDKDDEFTVALQYNF
>NZ_CP007567.1|WP_005329092.1|2510910_2512983_+|ATP-dependent-DNA-helicase-DinG
MLSTRLKTTIRNTYRQIADGLPGFVPRKEQNFLVAEIAKTLTGEYEKSRRILVAEAGTGIGKSLSYAQGAIPVARLTQKKLVISTATVALQEQLIHKDLPFYHRHSELPFRFMLVKGRQRYCCEHLLEQAASGAEMANFELDFGSLSKHKPSDSDKERYQALWQAYTEGKWDGDRDNWPKPIPDLCWDRIAADRHSCNKALSHHQHCPFHRARNDMDAADVLVVNHALLLSDLTMGGGIILPPPDECIYVLDEAHHLPTITRDHGAASASIKGSCRWLEKLVQSAGKLARALNKESLIDPQLKLQDALASLQPDLKALEQWLAGNDHLFGSEQHHRFAEGVLPDPLPMLAENLKEASKKALRALDRMQGAIGEALKDGEIRRKEAEPLLAESGFHLQRLESFCALWEMLSRHVPSGKTPLARWMARSEDGDIWLHASPIEVGYLLEEWLWSRCLGAVLVSATLTALSSFSYFRHQVGLKEHDGTRYLRLRSPFEYHKAELYLPKMTHEPSAPGFTQELVDTLPRLLAGKEASLVLFSSYRQMNEVAVGLRAKGLSLLVQGEASRNALLTLHKQKCDGGQASILFGTGSFSEGLDLPGHYLTNLVITKLPFAVPNSPVEEATAEWVEKRGGNPFLQLTVPEASRKLIQACGRLIRKEADRGRVTILDRRLLTKRYGKGLLDALPPFTRRIE
>NZ_CP007567.1|WP_005329090.1|2513127_2513787_+|DUF2057-domain-containing-protein
MKLTVLVPALAGLLWAGSALADSQLEISNPYVVQLIDGESINPKLLDKSSTFPISAGKHQVVVAFEGNYSSRSEIKLVTAEPLVINFTAGDNQKLVLDFKKPRNEDEAKAFVKEQKVVLKDKVSGQALASEQFIMPKVGGFQLTRDYQQELLKMGKAFNQPATVAVSSAAVMAAASAPVEVAPSKAQSNPEALTQLQSWYNKADAETRKAFQIWVIQQQ
>NZ_CP007567.1|WP_005329089.1|2513860_2514757_+|histone-deacetylase
MSLRIFYHPYYSSLTLPERHRFPLAKYQAIYQHLAALGYPLAEAPAASREQIARVHDADYVEAALTGQLEREAIRRLGFPWSPMLIERTLRSVGATVAASRHALEQGCGLQISGGYHHAHRDFGSGFCLFNDLVIAARACLDEGSCEQVLIVDLDVHQGDGSAALCTGSQDIITLSLHGEHNFPHHKPASHLDFALPSGMEDDAYLETLSQALNLALRLYHPDLILYQAGVDVHQADELGYLSLSDAGVRQRDAMVFDCAISNGLPIAAVPGGGYRRDWRQLIPLHLSLFEEAKKRYG
>NZ_CP007567.1|WP_041206030.1|2514916_2516065_-|MFS-transporter
MTTYSRPVLLLLCGLLLLTLAIAVLNTLVPLWLAHDQLPTWQVGMVGSAYFCGNLLGTLLAGALIKRAGFNRSYYLASLIFAAGCVGLGVTLGFWSWLTWRFIAGIGCAMIWVVVESALMCSGNARNRGRLLAAYMMVYYLGTVLGQLLVSTLPTALMDVLPWVTGLVLAAILPLLFTRIVSEQGELQGATRVWPMLRLRQARLGVNGCIISGIVLGSLYGLMPLYLNHQGVSDAGIGYWMAVMVSAGILGQWPAGRLADRFGRLPVLRMQVLVVILGALAMLGNLAMGPALFILGAAGFTLYPVAMAWACERVEQHQLVAMNQALLLSYTIGSLLGPAYTALLMQHYSDNLLFIMIASVSFIYLLMLLRPVGEHPTPVAHA
>NZ_CP007567.1|WP_041206031.1|2516306_2517257_-|ribosome-biogenesis-GTPase-YlqF
MSINWFPGHMHKARKEIAEVMPQVDVIIEMLDARIPFSSENPLVPELRGDTPVIKVLNKADLADPAITELWVAHMEQEKGIKALPLTQQEPEKIKALLTLCHEMLPERNFDLRGVRAMIMGIPNVGKSTLINTLAGRIIARTGNEAGVTKSQQRIKLDNNVILTDTPGFLWPKLNPPSCGYRLAITAAIKDTVFDYADIAMFAADYFLKAYPERIKARYQIAELPETEIELLELIARQRAFMRKGGLADLHKASEILVNEFRSGMLGRISLETPEMVSAEIVLAAEEAEQKAKEKAEREEERQARARRKYARKRQK
>NZ_CP007567.1|WP_041206032.1|2517583_2518975_+|alkaline-phosphatase
MRNMAGLAVMIGATLVAGCNSNNDSSTPEPSAKNVIFFLGDGMGLNTLTAARIYGVGEEGSLTIDTLPETAFIKTFSHDAQVTDSAPSMAAYMTGVKSNNGVISMDSDATYESDCSQSAGKPVTTLLELAKADGRGTGVVTSTRVTHATPAATYAHICNRDLEADIAAQLVPGGAGYNGALKEGLDVVLGGGSSFFLPKADKGKREDGRNLIDEMQAKGYQFASTLDELNQAEAGKPLLGLFGSSHMKYDLDRPASEPSLAQMTLAAIKQLKDKEKGYFLMVEGGRIDHALHDTNAKRALQDTLAFDDAIKATLDEVKKTDPELKNTLIVVTADHDHTLVLNGYAKRTGKTTAGNPGVLGLVKNYETGEPSKDSDGMPYTIIGFGNGYNRVDGPRSSVAPLDDATVSADDYHQEVVVKVGEIGNETHGGTDVFLGAIGQGADSFHGSLDNTAVFGKVKAAAKL
>NZ_CP007567.1|WP_005329077.1|2518998_2520366_+|alkaline-phosphatase
MNKTLVCTALFATLGGLSQAQASDAKNVILFIGDGMGPSVLTATRLYKVGEEGNLEIMSLPRSARIKTFSHDAQTTDSAPSMAAYTTGVKMNNEVIAMSSNTKAVAPSKDANGNKGINNCTGDNGTPVPTILELAKAAGKSVGAVTTTELTHATPAATYAHICHRDAAYAIAEQAVPGGAGFNAALGDGVDVLMGGGANHWTPYSASNKGGRADGRDLTAELGAQGYQYVTTQSDLAKIESGKVLGLFSAKSHLDYELDRVAKGAANTQPSLSEMTAKAIDLLSQNSQGYFLMVEGGRIDHALHATNAKRSLTDAVALDEAVKTALGKVDLADTLIVVTADHDHTMTINGYAAKGNPVLDLVKNGDGSTQNDVDGKPFTTLVFGNGPNRADVRPTLTSDQVMADDYLQETGVKLGSETHGGGDVMLFADGAGSGRFKGTLDNTLVFGKLKEALGL
>NZ_CP007567.1|WP_041206033.1|2520416_2521100_+|hypothetical-protein
MMRLLLSIWLLGCTLSFPLLADEAPDLAARIRYQDRITGSDGIARESVWQEKWLRVGNQVWSQRLIPLPLARAYHATHDATPGRKHFTHQMAARWVTLDDGGDLQLRYADAWHNQLVEVPPEEYGQVAFKPDWERIRYLVNPALLQEMTPLDEQAPEQTRWYEKREGKQRTRILWSSRWQLPLVVESASLDGYRSYRMEVTLKPLPRQLPWQQLGGYQTLDLRDFFD

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Crispr_ID: NZ_CP007567_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_6

2540250-2540354

TypeV-U4

Consensus_repeat	Method
ATGCCTTAGCCGTTGAACCGACCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_6

>merge|NZ_CP007567|6|2540250-2540354|CRISPRCasFinder
ATGCCTTAGCCGTTGAACCGACCGGTAATCTGTTTATTGATGCTCATCTTGTTCATACCAATAACCCTTGTTGCACCAACCATGCCTTAGCCGTTGAACCGACCG

>NZ_CP007567|6|6|2540250-2540354|CRISPRCasFinder
ATGCCTTAGCCGTTGAACCGACCG	GTAATCTGTTTATTGATGCTCATCTTGTTCATACCAATAACCCTTGTTGCACCAACC
ATGCCTTAGCCGTTGAACCGACCG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_041206039.1\|2536264_2537164_-\|homocysteine-S-methyltransferase-family-protein	unknown	unknown	gnl\|CDD\|376828
NZ_CP007567.1\|WP_005328827.1\|2539513_2540224_-\|phosphate-signaling-complex-protein-PhoU	unknown	unknown	gnl\|CDD\|182974
NZ_CP007567.1\|WP_005325257.1\|2548985_2550593_+\|malate-synthase-A	unknown	unknown	gnl\|CDD\|236432
NZ_CP007567.1\|WP_005330345.1\|2530521_2531481_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NZ_CP007567.1\|WP_103244595.1\|2545410_2546840_+\|IS66-like-element-ISAeme23-family-transposase	unknown	unknown	gnl\|CDD\|376980
NZ_CP007567.1\|WP_005328832.1\|2537438_2537981_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_041206041.1\|2541321_2542971_-\|phosphate-ABC-transporter-permease-PstA	unknown	unknown	gnl\|CDD\|227318
NZ_CP007567.1\|WP_005328825.1\|2540395_2541214_-\|phosphate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|184582
NZ_CP007567.1\|WP_041207009.1\|2532514_2533354_+\|sterol-desaturase-family-protein	unknown	unknown	gnl\|CDD\|225546
NZ_CP007567.1\|WP_041205358.1\|2533473_2534802_+\|IS4-like-element-ISAeme12-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP007567.1\|WP_081805723.1\|2546994_2547534_-\|tRNA-adenosine(34)-deaminase-TadA	unknown	unknown	gnl\|CDD\|182786
NZ_CP007567.1\|WP_041206038.1\|2531570_2532314_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NZ_CP007567.1\|WP_041205051.1\|2552032_2553370_-\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP007567.1\|WP_005325258.1\|2550666_2551980_+\|isocitrate-lyase	unknown	unknown	gnl\|CDD\|237893
NZ_CP007567.1\|WP_167332172.1\|2548141_2548282_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_005330342.1\|2529635_2530424_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270347
NZ_CP007567.1\|WP_042649944.1\|2553522_2554266_-\|DnaA-inactivator-Hda	unknown	unknown	gnl\|CDD\|181224
NZ_CP007567.1\|WP_041206042.1\|2542988_2545226_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226956
NZ_CP007567.1\|WP_005328837.1\|2534854_2536255_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|129983
NZ_CP007567.1\|WP_041206040.1\|2538001_2539321_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_041206039.1\|2536264_2537164_-\|homocysteine-S-methyltransferase-family-protein	gnl\|CDD\|376828	pfam02574, S-methyl_trans, Homocysteine S-methyltransferase. This is a family of related homocysteine S-methyltransferases enzymes: 5-methyltetrahydrofolate--homocysteine S-methyltransferases also known EC:2.1.1.13; Betaine--homocysteine S-methyltransferase (vitamin B12 dependent), EC:2.1.1.5; and Homocysteine S-methyltransferase, EC:2.1.1.10,.	2.36871e-71
NZ_CP007567.1\|WP_005328827.1\|2539513_2540224_-\|phosphate-signaling-complex-protein-PhoU	gnl\|CDD\|182974	PRK11115, PRK11115, phosphate signaling complex protein PhoU.	3.817e-160
NZ_CP007567.1\|WP_005325257.1\|2548985_2550593_+\|malate-synthase-A	gnl\|CDD\|236432	PRK09255, PRK09255, malate synthase; Validated.	0
NZ_CP007567.1\|WP_005330345.1\|2530521_2531481_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.29772e-88
NZ_CP007567.1\|WP_103244595.1\|2545410_2546840_+\|IS66-like-element-ISAeme23-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	1.37593e-40
NZ_CP007567.1\|WP_041206041.1\|2541321_2542971_-\|phosphate-ABC-transporter-permease-PstA	gnl\|CDD\|227318	COG4985, COG4985, ABC-type phosphate transport system, auxiliary component [Inorganic ion transport and metabolism].	6.42953e-93
NZ_CP007567.1\|WP_005328825.1\|2540395_2541214_-\|phosphate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|184582	PRK14236, PRK14236, phosphate transporter ATP-binding protein; Provisional.	0
NZ_CP007567.1\|WP_041207009.1\|2532514_2533354_+\|sterol-desaturase-family-protein	gnl\|CDD\|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	2.42205e-38
NZ_CP007567.1\|WP_041205358.1\|2533473_2534802_+\|IS4-like-element-ISAeme12-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	1.22754e-26
NZ_CP007567.1\|WP_081805723.1\|2546994_2547534_-\|tRNA-adenosine(34)-deaminase-TadA	gnl\|CDD\|182786	PRK10860, PRK10860, tRNA-specific adenosine deaminase; Provisional.	1.03106e-88
NZ_CP007567.1\|WP_041206038.1\|2531570_2532314_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.53714e-153
NZ_CP007567.1\|WP_041205051.1\|2552032_2553370_-\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	1.77276e-31
NZ_CP007567.1\|WP_005325258.1\|2550666_2551980_+\|isocitrate-lyase	gnl\|CDD\|237893	PRK15063, PRK15063, isocitrate lyase; Provisional.	0
NZ_CP007567.1\|WP_005330342.1\|2529635_2530424_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270347	cd13629, PBP2_Dsm1740, Amino acid-binding domain of the type 2 periplasmic binding fold superfamily. This subfamily includes the periplasmic binding protein type II (BPBII). This domain is found in solute binding proteins that serve as initial receptors in the ABC transport, signal transduction and channel gating. The PBPII proteins share the same architecture as periplasmic binding proteins type I (PBPI), but have a different topology. They are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBPII proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the family includes ionotropic glutamate receptors and unorthodox sensor proteins involved in signal transduction.	1.04838e-131
NZ_CP007567.1\|WP_042649944.1\|2553522_2554266_-\|DnaA-inactivator-Hda	gnl\|CDD\|181224	PRK08084, PRK08084, DnaA inactivator Hda.	8.51957e-112
NZ_CP007567.1\|WP_041206042.1\|2542988_2545226_-\|ABC-transporter-permease-subunit	gnl\|CDD\|226956	COG4590, COG4590, ABC-type uncharacterized transport system, permease component [General function prediction only].	0
NZ_CP007567.1\|WP_005328837.1\|2534854_2536255_-\|amino-acid-permease	gnl\|CDD\|129983	TIGR00905, Arginine/ornithine_antiporter, transporter, basic amino acid/polyamine antiporter (APA) family. This family includes several families of antiporters that, rather commonly, are encoded next to decarboxylases that convert one of the antiporter substrates into the other. This arrangement allows a cycle that can remove proteins from the cytoplasm and thereby protect against acidic conditions. [Transport and binding proteins, Amino acids, peptides and amines].	4.79538e-158
NZ_CP007567.1\|WP_041206040.1\|2538001_2539321_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	3.06882e-134

>NZ_CP007567.1|WP_005328827.1|2539513_2540224_-|phosphate-signaling-complex-protein-PhoU
MDNMNLNKHISGQFNAELENVRNQVLVMGGLVEQQLADAISAIHIQDLDAARKIVANDHKVNAMEVAIDEECTRIIAKRQPTASDLRLVMAIIKTITDLERIGDVADKIARMLTDNANKPQPPLVSLENMGRRTIKMLHDVLDAFARMDLEAAIAVYKEDDKVDREYESIIRELMTYMMEDPRTIPQVLNVLWAARAIERVGDRCQHICEYIVYYVKGKDVRHTKADELSDLLGKH
>NZ_CP007567.1|WP_041206040.1|2538001_2539321_-|HlyC/CorC-family-transporter
MSFADSLFFLMLLVAGSVFFSLSEISLAASRKIKLQVMADEGNRHAEKVLALQAQPGNFFTVVQIGLNTVAILGGILGESALNPAIKQFVAGFYQGPWLGQISSAASFVFVTGMFILIADLMPKRLAMTMPERIAVVVVRPMLLCVTLLMPLVWFFNGLANALFRLLRVSMVRNDEITSDDIYAVMDAGAEAGVIQREEHQLIENVFELQSLGVTSAMTARESLIYFTLQEGEESIKAKIAEHPHNKFLVCDHNLDSIKGFVDAKELLIRVISGQSIDLNSGSLVQSVIIIPDTLNLYEAMEYFKNHRGDFAVVMNEYALVVGIVTMNDLMSTVMGEWATHVVEEQIVQRDENSWLVDGVTPISDVMRAFDIEEFPESQNYETIAGFIMFMLRKIPKRTDSVKYAGYKFEVVDIDSYKIDQLLVTRVEPVLAEKPALES
>NZ_CP007567.1|WP_005328832.1|2537438_2537981_-|hypothetical-protein
MKMPSYSRALACVALALALGACSQSAPRKSAAAPKPAAPKAVAVVPQPDPDAVVQSAVAEPSPVFDEEYHGPDQGSLESVTALFARGYIESAMRETMLAAVHSDYPLLGMRDVRLTDPVAKFLTSAQARTTAHDYLYAGVQRRLGRPLSPAQWEQIWQGYPQQGRVSDWVKQTKRVLAGR
>NZ_CP007567.1|WP_041206039.1|2536264_2537164_-|homocysteine-S-methyltransferase-family-protein
MDTKDLWVLDGGMGRELARRGAPFRQPEWSALALMEASETVREVHQAYAASGARVITTNSYALVPFHIGAERFAAEGERLAALAGQLAREVADEQGAVQVAGSLPPLFGSYRADLFDAGRVSELATPLIRALSPHVDLWLAETMSLIAEPLALKALLPEDGKPFWVSFTLEDEAPGSEPTLRSGERVADAVTALASAGVDAILFNCCQPEVIEGALKVAGAVLQAQERTDVRLGAYANAFPPQPKEATANDGLDEIRGDLGPLDYLGWAERWRGAGASLIGGCCGIGPEHIQALASRLR
>NZ_CP007567.1|WP_005328837.1|2534854_2536255_-|amino-acid-permease
MKESKIGLWSLTALVFSSMVGAGIFSLPQNMAEVAGARAVLIGWGVTGVGILALAASFLYLSRLRPGLDGGIYSYARAGFGDLVGFFSAWGYWLCATIGVVGYLVIAFAALGSFVDTSDNVWFGEGNTLAAFIGESCILWAVHLLVARGVQQAALFNLVATLAKSLPLLLFILFACYWFDPVTFAADQQGSTLAVPVSEQVRNTMLITLWVFTGIEGAAVLSARARNKRDVGTATVLGVVLALLLYVLISVLALGILSRPELAALPNPSMAGLMAQMTGSWGKVLISVGLIVSVLASYVSWTLFSAEVPFSAARHGAFPAIFRRQNRNGTPIASLWLTSLTVQGCLLLVWLLGKGYTNLLLISTSMILVPYLLIGLFLLKLSLSGEGNGLVRAVGLVSSGYGLWLLYAAGVEYLLLSLLLYGPGLLLFLYSRRQLGAEQRLSLRERLLAGITLVSLVPAIWSFAHV
>NZ_CP007567.1|WP_041205358.1|2533473_2534802_+|IS4-like-element-ISAeme12-family-transposase
MRIEQALDFLHASNMAQFESLSDLIPPALITSLLGEEGVATLRRRRMPMERLVWAIIGMAIFRNVPMTQLVNQLDILLPGDRPFVAPSAFLQARQKLGHKSIARLFHDTATRWHQQANHPGWAGLQLLAVDGVMWRTPDTPDNAAAFAKPGTQHGETAYPQVRMLCQMELTSHLLVQAVMESCAVNEMVLAEQLIARTPDHSLTLFDKGFYSLGLLHAWQRAGSERHWLLPLKKGTQYEVVRKLGRQDALVQLKTSPQARKKWPQLPEAIEARLLTRTINGKERQVLTSMVDPMRFPGADIVELYGHRWEIELGYREMKHSLQQHRLTLRSKKATGIRQELWGVLLAYNLLRSQMVKMAASLKGYTASQLSFHMASVYLIHELSCMPYVSPGNIPGRVAELEKQAGQFVLPARRERSYPRCVKPRPQKYSVKKANKNNASQA
>NZ_CP007567.1|WP_041207009.1|2532514_2533354_+|sterol-desaturase-family-protein
MDVQLLLLYLSPVFLAFVGWEMLYLRKHGAAFPSATYQWRDLFANAALALMHQGGDALTAIAIAYLYDGLWGWRLFDIELNAWSLLLLFLLQDLCYWLFHFASHHVRWLWASHVVHHSSERLNLSTAFRQSLMYPVSGMWLFWIPMILIGFPPEAVVATVLLSLGFQFFVHTQVVGKLGWLEWVFNTPSHHRVHHASNAKYIDRNFAGVLIIWDRLFGTFVEEDPTEPCRFGITKPVHSFNPLTLTFHEWRDMLRDARGLPWSEKLKVLFGKPAGPGNT
>NZ_CP007567.1|WP_041206038.1|2531570_2532314_+|amino-acid-ABC-transporter-ATP-binding-protein
MRKATDPIIKASGVEKFYGTEVHALKNVSTQVAEGEVVVIVGPSGSGKSTFLRTLNQLETINDGHIEVDGISLTEPGDVNKLREEVGMVFQSFNLFPHLNVLDNISLAPQKVRGLSRKEAEDRAKALLLKVGLSNKAQSYPSQLSGGQQQRVAIARALAMQPRIMLFDEPTSALDPEMVGEVLDVMKGLAKEGMTMVVVTHEMGFAREVADRVLFMESGELLVDEKPTDFFDNPPSPRLRQFLSQVL
>NZ_CP007567.1|WP_005330345.1|2530521_2531481_+|amino-acid-ABC-transporter-permease
MEKQPNLLLWHGVFLLMVLAAIFGIYKAVQAVDYTWRWERIPQYIAYQAEQKQYAEFDGTVVTGTTAAEKGQLFLQDDLDPNRRQAIASTGAQVAEGDTVFLGDTLDVQLSWTAGPIAWGVWVTVKLSLVAGVFAILLGTLAGLARLSPNPALRNLAVTYVELIRGTPLLVQIFIVYFFIGTVLNLDRFTAGVAALAVFTGAYVAEIVRAGISSIHKGQMEAGRSLGMTAAQTMRYVILPQAFKRVLPPLAGQFINLIKDSSLVSVISITDLTKAGREVVSSTFSPFEVWFTVALLYLVLTGTLSFLVRRLEVKYARSN
>NZ_CP007567.1|WP_005330342.1|2529635_2530424_+|transporter-substrate-binding-domain-containing-protein
MIKKLILSTLLLCGLANAAPSSTLDAVLERGVLRVGFDAGYQPFEMTNKQGQYIGFDVDLAKMVAKEMGVKVEFVNTAWDGIIPALLTDKFDVIMGGMTVTPQRNLRVNFADPYIVVGQTIVLRKDKAGEIKSFQDLNDPKYKIAVRLGTTGEQAVKRMIPKATLLQFETQDDAKLEVINGKVDAFVYDLPYNAIFASQNTGAVVHLDKPFTFEPMAWAIRKGDQDTLNWFNNYLRQIKGDGSYDRLYKKWFESNAWLNQLK
>NZ_CP007567.1|WP_005328825.1|2540395_2541214_-|phosphate-ABC-transporter-ATP-binding-protein
MINVTPTSTQHTALDLLNLSPEQTALEVKDLNLYYGNKQALFNVNMKIPKGQVTAFIGPSGCGKSTLLRCINRMNDLVEICRIEGEIQLHGHNIYDKSVDVSALRRQVGMVFQRPNPFPKSIYENVVYGLRLQGINDRRTLDEAAERSLRGAALWEEVKDRLHDNAFGLSGGQQQRLVIARAIAIEPEVLLLDEPTSALDPISTLTIEELINELKSQFTVVIVTHNMQQAARVSDQTAFMYMGELIEYSNTNTIFTTPAKKKTEDYITGRYG
>NZ_CP007567.1|WP_041206041.1|2541321_2542971_-|phosphate-ABC-transporter-permease-PstA
MGKWFKSGAPWIWMTGGAVSLSLVAVLGLLLLIGWRGLVYFWPHPIYEWQLEDASGNKSVLIGEINDREMVPVERLRAAGQALEGEERELLTRYLVKTGNREFVDLDFRWVLETDIKSRTQPAELAMVERTTNGNFYGYITSVKEDGRELTQDMHPALQRVLARANALSEQANDLQKGDIGGINYQLERLRLKERKAELEGELTDALKADLAAQRQALNDRYLVLEKELFSLRAQADRDAITVKDMRGELVTMPMSKVLDVVWPNDMSLPAKVGHWFHQIGKFVSDDPREANTEGGVFPAIFGTVFMVLLMAIIVTPLGVVAAVYLHEYAGKNSLTKIIRIAVINLAGVPSIVYGVFGLGFFVYTLGGSLDQLFYPEALPSPTFGSPGVIWSALTLAILTLPVVIVSTEEGLARIPSTIRQGSLALGATQAETLWRIVLPMASPAIMTGLILAIARAAGEVAPLMLVGVVKLAPTLPMDGNFPYLHVERKFMHLGFHIYDVGFQSPNVEAARPLVYATSFLLVTVIVGLNLTAIGIRNHLREKFRSLEH
>NZ_CP007567.1|WP_041206042.1|2542988_2545226_-|ABC-transporter-permease-subunit
MSSESLNLVMAGSRKRRIKDKLAKYGVTTGGALVLVALLLIFFYLLYVVKPIFNGASVEATSSFTLPTQGKTAWLGVEEQNEIGYRFNDQGQVSFFAIKADDNVKVGQVLGQTGVTGDVSAVAVPAPGQKLIAYGFADGKAIVVQPSFKVSYPNDVRVIEPSLQYPFGEEPVVIDPKGKALNRIVFEATKDKMATAAVTEDGRGVMTVMSGEENFLSGEVEWSSQNYSIPSLPRHVDQMLLTPNLRILFVREGNRLSVYDIHNLSDISLRDVMEINAPNADVTQVALLSGASSLLVGNDNGVISQWFEVAKDGKRQFTQIRDFKGDGPVALLTPEHFRKGFISAAKDGTINFFHATGEAKLLGETIEGGALAALAISPRHNLLLTQQGDTFKVFDVENDHPEVTWSALWQEVWYEGYPEPMYVWQSTSASNDFEAKLSLVPLVFGTLKASFYAMLFAVPLGVAGAIYTAYFMSAGLRKYVKPTVEIMAALPTVILGFLAGLWLAPIIEGALPGVILLLLLLPMGMLLTALVWNYLPERGRSWLPEGWHAILLIPVLLLIGWGAFALSPLIENAFMHGDSRIWLTHEMGIKFDQRNSLVVGIAMGFAVIPTIFSIAEDAVFSVPKHLTQGSLALGATPWQTLSRVVILTASPGIFSAVMMGLGRAVGETMIVLMATGNTPIMDFSMFQGLRTLAANIAVEMPESEVGSSHYRVLFLAAFVLFVFTFMFNTLAEFIRQRLREKYSSL
>NZ_CP007567.1|WP_103244595.1|2545410_2546840_+|IS66-like-element-ISAeme23-family-transposase
MNKKKLFENAAPQAHDLHDANRIIQELWNKLREYEDRLALSSRNSSKSPSSDSPAAKAERKKFATPRGRNQVGAQPGHPGHRRELSLLQSTDQVVACKPASCCAECGGEVVANAAPSFRHQVFELPKLPLEITEYQVFHGHCQHCDALSKGELPNSAPNGQMGPRLLSHIAVLAGKYHLSVRKIQSLLHDQYGMTFSVGAISEAQGRISSMLTPIHQALKQHIQKAPIIHADETTHQRNGESNTRWLWLMASNDAVFQNIRYFRSQDNAKHLLGSAPHGVVVTDQCASYHWLDPTRHQFCLAHVQRNLQEMADYGGGGQTAYLGHRLVVLLKTVFRTQHRYESGLIGEQIRLRRMERLRRSIKTVLCKGAEVPVRRYAGRCQHILKYETGLWVFLQHPGTPLTNNEAERCIRGSVILRKICFGTSSDRGDKFRSRVLSVIETSKKRQLSALEVLCRIVTAVMTGQPYPDVFNLTSA
>NZ_CP007567.1|WP_081805723.1|2546994_2547534_-|tRNA-adenosine(34)-deaminase-TadA
MKSSDVTEPVSQSEQDEHWMRHAMALAARAEGIGEIPVGAVLVLGDEVVGEGWNRSISAHDACAHAEIMAIRAAGITLENYRLLDTTLYVTLEPCCMCAGALIHSRVRRVVYGARDLKTGAAGSVFEILQDPRHNHSVELTGGVLAEACSAQLSDFFRRRRAEKKAAREALKQSGGPAV
>NZ_CP007567.1|WP_167332172.1|2548141_2548282_+|hypothetical-protein
MTQTVDTQPDQPLISSPHSELESTDASLGGTVHLDVIDLAAPDDDY
>NZ_CP007567.1|WP_005325257.1|2548985_2550593_+|malate-synthase-A
MSAPAQTISSTRLHIQGEMLPDYAQILTPDAVALVSELVERFAPQRNELLKQRVARQARIDGGELPDFLPETAHIRAGDWTIRGIPADLQDRRVEITGPVERKMVINALNANVKVFMADFEDSLAPAWNKVIEGQINLRDAVNGTVSYTSPEGKAYNLNADPAVLICRVRGLHLPEKHVTFDGAPIPGGLFDFALYFLHNHQALLAKGSGPYFYLPKLQSHLEGRWWSEVFAWTEDRFGLPRGTIKATVLIETLPAVFEMDELLYQMKDHIVALNCGRWDYIFSYIKTLKNHPDRVLPDRQVVTMDKPFLSAYSRLLIKTCHKRGALAMGGMAAFIPAKDPAVNAEVFAKVKADKEREANNGHDGTWVAHPGLADTAMAVFNAAILAGAKNQLGVLREQDAPITAADLLAPCEGERTEAGMRTNIRVALQYLEAWINGNGCVPIYGLMEDAATAEISRTSIWQWIRHGKSLSNGKVVTKALFRQMLAEEQVVVKAEVGEARWQAGRFAEAGELMEQITCADTLIDFLTLPGYERL
>NZ_CP007567.1|WP_005325258.1|2550666_2551980_+|isocitrate-lyase
MALTREQQIQAIEKDWAENPRWKGIKRGYSAEDVVNLRGSLQPVHTLAQRGADKLWELIHGGAKKGYVNCLGALTGGQAVQQAKAGIEAIYLSGWQVAADNNLSSTMYPDQSLYPANSVPSVVERINNSFARADQIQWANKVGPQDKGFIDYFLPIVADAEAGFGGVLNAFELMKGMIEAGAAGVHFEDQLASVKKCGHMGGKVLVPSQEAVQKLIAARLAADVCGTTTLVIARTDANAADLLTTDADPYDAGFLTGERTAEGFYKVQAGIEQAISRGLAYAPYADMVWCETAKPDLDEARQFAEAIKAQYPDKILAYNCSPSFNWKKNLDDATIARFQQELSDMGYKYQFITLAGIHNMWFHMYELAYQYARGEGMKHYVEMVQQPEFAAAERGYTFVAHQQEVGTGYFDKVTTVIQGGQSSVTALTGSTEEDQFH
>NZ_CP007567.1|WP_041205051.1|2552032_2553370_-|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNGPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIEKRPRPSRPRAVKISKTRFPVNRNAAPLK
>NZ_CP007567.1|WP_042649944.1|2553522_2554266_-|DnaA-inactivator-Hda
MIHLGANITVKAQRVKQPAQLSLAVQLPDDETFVSFYPGNNAHLITALKNAAIGQGAPFLYFWGAKGSGRSHLLHATCAEVNARDAAAAYLSLDQFEQLDPSMLDALESLPLVCLDSLEAIAGNTVWERALFDFYNRWKEKGEGTLVVTGCSAPRKLGLQLPDLASRLDWGVSFHLDELDDEGKLSALQLRAELRGFKLPIDVGRFLLNRLSRDMRTLLATLNQLDNASFRAKRKLTIPFVKEILEL

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Crispr_ID: NZ_CP007567_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_7

2819060-2819199

TypeV-U4

Consensus_repeat	Method
TCAGCCTCCGGTCGTTACTGGAAGGAGAGGGAAGAAGGCGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_7

>merge|NZ_CP007567|7|2819060-2819199|CRISPRCasFinder
TCAGCCTCCGGTCGTTACTGGAAGGAGAGGGAAGAAGGCGGCCTCATGCCAGTCCCACAGCGCCGTTGTGCGATCCACGGTCGTTATCTCGCTCATTCTCAGCCTCCGGTCGTTACTGGAAGGAGAGGGAAGAAGGCGGC

>NZ_CP007567|7|7|2819060-2819199|CRISPRCasFinder
TCAGCCTCCGGTCGTTACTGGAAGGAGAGGGAAGAAGGCGGC	CTCATGCCAGTCCCACAGCGCCGTTGTGCGATCCACGGTCGTTATCTCGCTCATTC
TCAGCCTCCGGTCGTTACTGGAAGGAGAGGGAAGAAGGCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_041206120.1\|2808284_2810015_+\|formate--tetrahydrofolate-ligase	unknown	unknown	gnl\|CDD\|237404
NZ_CP007567.1\|WP_005325504.1\|2816967_2817648_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226629
NZ_CP007567.1\|WP_005325498.1\|2812006_2812663_-\|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl\|CDD\|236472
NZ_CP007567.1\|WP_041206129.1\|2826414_2826924_-\|ferredoxin-type-protein-NapF	unknown	unknown	gnl\|CDD\|319886
NZ_CP007567.1\|WP_041206121.1\|2815065_2815845_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|211851
NZ_CP007567.1\|WP_005325509.1\|2819497_2819992_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NZ_CP007567.1\|WP_005325518.1\|2822751_2823486_-\|ferredoxin-type-protein-NapG	unknown	unknown	gnl\|CDD\|236534
NZ_CP007567.1\|WP_005325496.1\|2810087_2811737_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NZ_CP007567.1\|WP_005325505.1\|2817757_2818486_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270257
NZ_CP007567.1\|WP_041206124.1\|2821424_2821880_-\|nitrate-reductase-cytochrome-c-type-subunit	unknown	unknown	gnl\|CDD\|367715
NZ_CP007567.1\|WP_041204444.1\|2826115_2826382_-\|chaperone-NapD	unknown	unknown	gnl\|CDD\|367731
NZ_CP007567.1\|WP_041206127.1\|2823499_2825989_-\|nitrate-reductase-catalytic-subunit-NapA	unknown	unknown	gnl\|CDD\|237416
NZ_CP007567.1\|WP_041207033.1\|2820073_2820601_-\|molybdenum-cofactor-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|131715
NZ_CP007567.1\|WP_041206126.1\|2821879_2822755_-\|quinol-dehydrogenase-ferredoxin-subunit-NapH	unknown	unknown	gnl\|CDD\|236535
NZ_CP007567.1\|WP_005325513.1\|2820822_2821413_-\|cytochrome-c3-family-protein	unknown	unknown	gnl\|CDD\|131216
NZ_CP007567.1\|WP_005325507.1\|2819255_2819501_-\|molybdopterin-synthase-sulfur-carrier-subunit	unknown	unknown	gnl\|CDD\|182985
NZ_CP007567.1\|WP_005325500.1\|2813015_2814248_+\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|182643
NZ_CP007567.1\|WP_005325501.1\|2814244_2815000_+\|molybdopterin-synthase-adenylyltransferase-MoeB	unknown	unknown	gnl\|CDD\|180204
NZ_CP007567.1\|WP_005325503.1\|2815915_2816971_-\|molybdenum-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|131197
NZ_CP007567.1\|WP_005325506.1\|2818570_2819056_-\|molybdopterin-synthase-catalytic-subunit-MoaE	unknown	unknown	gnl\|CDD\|182642

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_041206120.1\|2808284_2810015_+\|formate--tetrahydrofolate-ligase	gnl\|CDD\|237404	PRK13506, PRK13506, formate--tetrahydrofolate ligase; Provisional.	0
NZ_CP007567.1\|WP_005325504.1\|2816967_2817648_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|226629	COG4149, ModC, ABC-type molybdate transport system, permease component [Inorganic ion transport and metabolism].	2.83186e-76
NZ_CP007567.1\|WP_005325498.1\|2812006_2812663_-\|GTP-cyclohydrolase-I-FolE	gnl\|CDD\|236472	PRK09347, folE, GTP cyclohydrolase I; Provisional.	5.15544e-104
NZ_CP007567.1\|WP_041206129.1\|2826414_2826924_-\|ferredoxin-type-protein-NapF	gnl\|CDD\|319886	cd10564, NapF_like, NapF, iron-sulfur subunit of periplasmic nitrate reductase. This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.	8.05609e-64
NZ_CP007567.1\|WP_041206121.1\|2815065_2815845_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|211851	TIGR03611, RutD, pyrimidine utilization protein D. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the hydrolase, alpha/beta fold family defined by pfam00067.	2.23931e-22
NZ_CP007567.1\|WP_005325509.1\|2819497_2819992_-\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	4.71655e-101
NZ_CP007567.1\|WP_005325518.1\|2822751_2823486_-\|ferredoxin-type-protein-NapG	gnl\|CDD\|236534	PRK09476, napG, quinol dehydrogenase periplasmic component; Provisional.	7.42628e-153
NZ_CP007567.1\|WP_005325496.1\|2810087_2811737_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.01719e-71
NZ_CP007567.1\|WP_005325505.1\|2817757_2818486_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270257	cd13539, PBP2_AvModA, Substrate binding domain of ModA/WtpA from Azotobacter vinelandii and its closest homologs;the type 2 periplasmic binding protein fold. This subfamily contains domains found in ModA proteins that serve as initial receptors in the ABC transport of molybdate in eubacteria and archaea. Bacteria and archaea import molybdenum and tungsten from the environment in the form of the oxyanions molybdate (MoO(4) (2-)) and tungstate (WO(4) (2-)). After binding molybdate with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. In contrast to the structure of the two ModA homologs from Escherichia coli and Azotobacter vinelandii, where the oxygen atoms are tetrahedrally arranged around the metal center, the structure of Pyrococcus furiosus ModA/WtpA (PfModA) has shown that a binding site for molybdate and tungstate is where the central metal atom is in a hexacoordinate configuration. This octahedral geometry was rather unexpected. The ModA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.22627e-76
NZ_CP007567.1\|WP_041206124.1\|2821424_2821880_-\|nitrate-reductase-cytochrome-c-type-subunit	gnl\|CDD\|367715	pfam03892, NapB, Nitrate reductase cytochrome c-type subunit (NapB). The napB gene encodes a dihaem cytochrome c, the small subunit of a heterodimeric periplasmic nitrate reductase.	2.73122e-65
NZ_CP007567.1\|WP_041204444.1\|2826115_2826382_-\|chaperone-NapD	gnl\|CDD\|367731	pfam03927, NapD, NapD protein. Uncharacterized protein involved in formation of periplasmic nitrate reductase.	1.25276e-26
NZ_CP007567.1\|WP_041206127.1\|2823499_2825989_-\|nitrate-reductase-catalytic-subunit-NapA	gnl\|CDD\|237416	PRK13532, PRK13532, nitrate reductase catalytic subunit NapA.	0
NZ_CP007567.1\|WP_041207033.1\|2820073_2820601_-\|molybdenum-cofactor-biosynthesis-protein-B	gnl\|CDD\|131715	TIGR02667, Molybdenum_cofactor_biosynthesis_protein_B., molybdenum cofactor biosynthesis protein B, proteobacterial. This model represents the MoaB protein molybdopterin biosynthesis regions in Proteobacteria. This crystallized but incompletely characterized protein is thought to be involved in, though not required for, early steps in molybdopterin biosynthesis. It may bind a molybdopterin precursor. A distinctive conserved motif PCN near the C-terminus helps distinguish this clade from other homologs, including sets of proteins designated MogA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.73657e-91
NZ_CP007567.1\|WP_041206126.1\|2821879_2822755_-\|quinol-dehydrogenase-ferredoxin-subunit-NapH	gnl\|CDD\|236535	PRK09477, napH, quinol dehydrogenase membrane component; Provisional.	2.47826e-151
NZ_CP007567.1\|WP_005325513.1\|2820822_2821413_-\|cytochrome-c3-family-protein	gnl\|CDD\|131216	TIGR02161, Cytochrome_c-type_protein_NapC, periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family. Nearly every member of this subfamily is NapC, a predicted membrane-anchored four-heme c-type cytochrome that forms one component of the periplasmic nitrate reductase along with NapA, NapB, NapD, NapE, and NapF subunits. A single known exception at this time is NirT, which is instead a component of a nitrite reductase. This family excludes TorC subunits of trimethylamine N-oxide (TMAO) reductases.	8.30223e-122
NZ_CP007567.1\|WP_005325507.1\|2819255_2819501_-\|molybdopterin-synthase-sulfur-carrier-subunit	gnl\|CDD\|182985	PRK11130, moaD, molybdopterin synthase small subunit; Provisional.	2.76853e-54
NZ_CP007567.1\|WP_005325500.1\|2813015_2814248_+\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|182643	PRK10680, PRK10680, molybdopterin biosynthesis protein MoeA; Provisional.	0
NZ_CP007567.1\|WP_005325501.1\|2814244_2815000_+\|molybdopterin-synthase-adenylyltransferase-MoeB	gnl\|CDD\|180204	PRK05690, PRK05690, molybdopterin biosynthesis protein MoeB; Provisional.	9.34517e-158
NZ_CP007567.1\|WP_005325503.1\|2815915_2816971_-\|molybdenum-ABC-transporter-ATP-binding-protein	gnl\|CDD\|131197	TIGR02142, Molybdenum_import_ATP-binding_protein_ModC, molybdenum ABC transporter, ATP-binding protein. This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions].	2.8742e-92
NZ_CP007567.1\|WP_005325506.1\|2818570_2819056_-\|molybdopterin-synthase-catalytic-subunit-MoaE	gnl\|CDD\|182642	PRK10678, moaE, molybdopterin synthase catalytic subunit MoaE.	4.67389e-78

>NZ_CP007567.1|WP_005325506.1|2818570_2819056_-|molybdopterin-synthase-catalytic-subunit-MoaE
MSQATTTPTDRILVQRADFSLGEEYERLATRHDSGAIVTFVGKVRDFNQGDAVKGLSLEHYPGMTEKALVDIVNQARARWPLQECTLIHRIGDLLLGDQIVLVAVSSAHREAAFEACHFIMDFLKTRAPFWKKELTAEGIQRWVEAKQSDDAAAARWRQDP
>NZ_CP007567.1|WP_005325505.1|2817757_2818486_-|molybdate-ABC-transporter-substrate-binding-protein
MKKQLSVVLLGLVAGALYSGAAQADEVKVAVAANFKGTMERIGKAFTAKTGHRVVISSAATGVLYTQITHGAPFDIFLSADVATPQKLEAEGKGSDRFTYAIGQLGLWKKGGPAPDETTLRSWKGNLAIANPKTAPYGTAAMATLARLKIDPKQYRVLTGTNISQTWQFVDTGNAELGFVAWANLVEAGKTGEAWAVPASFYPPIEQQGLILKKGAAVEALVAWLKGPGQEQIKAAGYALPQ
>NZ_CP007567.1|WP_005325504.1|2816967_2817648_-|molybdate-ABC-transporter-permease-subunit
MSEGDLQAVWLTLKLAASTTAILLLLSPPLAWWLSRSQHRLRPLVEALVALPLVLPPTVLGFYLLLAFSPEYGLGAWWRETFGTPLAFSFLGLLFASILYSLPFVVQPLTSAFVNMGNKEIEAAATLGLGPLERFFQIILPMTLPSFVMAAALGFAHTLGEFGVVLMIGGNIPGETQVLSIALFDHVEAMDYQHAHYLAGGLMGFSLVMLVLVYGVLQRRQRRLFG
>NZ_CP007567.1|WP_005325503.1|2815915_2816971_-|molybdenum-ABC-transporter-ATP-binding-protein
MSLHLKAWRRFGGFELDCDLTLPLGGILGLFGPSGCGKSTLLRIIAGLDRAPSDVLHWQGRDLAALLPEARRIGLVFQDSRLFPHMTVLGNLQLAAGKGRGRWQHEALAMRLGFADLLGQPAHGLSGGQRQRVALGRALLAEPDLLLLDEPFSALDSRSRIHQAHVLKGLQRESGIPMIFVSHAMEEVSLLCDQLVLQEGGRVEAQGRPSEIFARTDLSLASRDDAGVMLTATLAHYDDAEQMATLQLGDQTLMVTMEHAPDETGELQIKVAGRDLVIATAPIVHSSLSNCLETRLLEAREVRPGQTLLQLALGQQILLARITSRSAQRLALVPGQRLYAYIKAVSLVGEG
>NZ_CP007567.1|WP_041206121.1|2815065_2815845_-|alpha/beta-fold-hydrolase
MRRNQVMKSHGLALRSAGEGPLLLLLHGLGSSSLDWQAQIEHFSQHYRVVALDLRGHGQSMQEGPFDVPTLAADVARWLEEQPEPAWVVGLSLGAMVALELALRLPHKVRGLVLVNGFSEFLLETPREQERHAMRLKWLRWFGMRPLAWWLGRELFPGPELAQVRHTFRLRFVRSNKKKTYKALLEALPGWSVRARLGSLWQPVAIISTSHDYLPLAKRVEQFASLPNASIHTPEGHHAWPAEDPAGFNHLLQRILATH
>NZ_CP007567.1|WP_005325501.1|2814244_2815000_+|molybdopterin-synthase-adenylyltransferase-MoeB
MSEILSDAELLRYNRQIILKSFDFEGQEALKQARVLVIGAGGLGCAASQYLAVAGVGRLTLVDFDRVELSNLQRQVLHSDERIGMYKVDSAAQSLRALNPWLEVETHALLADEALLDALLPGHQLVLDCTDNVTIRNLLNQRARQHRVPLVSGAAIRLEGQLCSFTWQEDEPCYACLSALFGEQALTCVEAGVLAPVVGLVGSLQALEAIKLLAGMGKSHHGRLLMIDGLSSRFRELKLPKRPDCPVCSQP
>NZ_CP007567.1|WP_005325500.1|2813015_2814248_+|molybdopterin-molybdotransferase-MoeA
MMMGFDTGALLPLDKALQGMLEQLTCCCETEQLPLPQALDRILAEEISSPLSVPPFDNAAMDGYAVRLADLAAGAPLPVAGKAFAGQPYEGEWPAGHCIRIMTGAPVPAGTEAVVMQEETQEGGNGITFLTTPFLGQNIRRRGEDMAQGSRVLASGLRLSPRELPLLASLGIATVTVRRPLKVAIFSTGDELKPLGTPLAHGDIYDSNRYGVKAMLTRMGIACLDLGIIPDDPAALRAAFIQADREADALITTGGVSVGEADFTKQLLEELGEIGFWKLAIKPGKPFAFGRLPNVWFFGLPGNPVSAMVTFDQLVQPALARLAGHHFARPLPLQAIATEPLKKAPGRLDFQRGMLSQGPNGLEVRSTGSQDSGVFSSLSRANCYIVLEQERGKVAAGETVTVEPFSGLLL
>NZ_CP007567.1|WP_005325498.1|2812006_2812663_-|GTP-cyclohydrolase-I-FolE
MTSLSQEALLVRAALEAQGLETPLVANELNGQQKKEKIEGHMRAIMETLGLDLADDSLAETPHRIAKMYVNEIFSGLDYATFPKVTVIENKMKVDEMIMVRDISLTSTCEHHFVTIDGLAHVAYIPRGKVIGLSKINRIVQFFARRPQVQERLTQQILLALQTLLGTKDVAISIKATHFCVKARGVMDSTSYTTTTSLGGVFKTQPDTRAEFLGGLKG
>NZ_CP007567.1|WP_005325496.1|2810087_2811737_-|methyl-accepting-chemotaxis-protein
MNTMTIGKKLSAGFAVLGLMMAFIGGFSLLEFSTMNRAAIGFTDSILPAVVRTSTLGETINAVRRYELDVFLVADDPQQQAHYRNESEKSLQEAARQITAHDGTIWAEDLEERRTFDIVKADWEKYLGLHQRIRQMQDSGQMAEAQHLFMGEGVTLYTNLAKSVGDLVRINHGYADASRKVVVAAYDSAKLSVTLSLLVGLVLVVCLSVVLTRQIRDPLIMLARQAQRIASGDLGKSELQEWIRTSRFNRDELGQLGSAIDRMQGALASLVSEIAGSVSQLSSAVEEVSAISEQSAKGMASQQSEVSQVATAMNEMQSTVNEVARNTTDAMSAAKEASRTSTQGNQVVRSAIGSIEQVSQQIEQAGTVVSQLEADSASISMVLDVIRGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQASTAEISKMIALLQERTAEAGNAMQLSRQQMQESVGLAREAGGSIDSINGAVTQISDMNTLIATATEEQNAVTEELNRSIVNIHNAADENAQGAQQTAQACVELSKLANSLHQMTQRFTL
>NZ_CP007567.1|WP_041206120.1|2808284_2810015_+|formate--tetrahydrofolate-ligase
MLSDIEISRQSPRLSIQALAERLAIQPHQLSPQGHHKGKLSLELLKSRPGRAGQLVLVSAITPTPLGEGKTVTTLGLSMGLNHIGQPSIATIRQPSLGPVFGVKGGAAGGGHAQVVPMEEMNLHLTGDFHALSAAHNLAAAALDARLFHEQKLGEQFSARTGLSRLEIDPANILWPRTLDMNDRALRHLTLGQGGPADGVERSDRFVITAASELMAILALASDLKDLRARIGRIQLALDNRGNPITAEQLEVAGAMTVLLKDALQPTLMQTTEQTPVLVHAGPFANIAHGNSSVIADRIALGLTDYVVTEAGFGSDMGLEKFFNIKSRQSGITPACVVLVATVRGLKANSGLLDIRPGQPLPASLLGEDFPTLKQGCANLAWHIQNARRYGVPVVVAINRFPTDSQAELDLLAREALAAGACDAAISHAFTDGGKGASELARAVVAACEQPSQVKLLYPNEMSLAAKLATLVECGYGGRGVRLSDKARQQLVRLSAEGWDHLPICVAKTPLSISHDPTLKGVPTDFEVPIDEVRLCAGAGFVYALAGPIMTMPGLGSLPAYRHIDIDENGEIVGLS
>NZ_CP007567.1|WP_005325507.1|2819255_2819501_-|molybdopterin-synthase-sulfur-carrier-subunit
MIKVLFFAQVRELVGCDELSLPSDYPTAEQLRAALCERGDKWALALESGKLLVAVNQTLVPLETALNDGDEVAFFPPVTGG
>NZ_CP007567.1|WP_005325509.1|2819497_2819992_-|cyclic-pyranopterin-monophosphate-synthase-MoaC
MNLTHLNQSGEAHMVDVTDKQVTEREARAEAFVTMAPATLALILGGQHHKGDVFATARIAGIMAAKKTADLIPLCHPLALTRVEVEIDAQPEHNRVHIRTLCKLSGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIEQVRLVEKKGGKSGHFQLGSQAGEKA
>NZ_CP007567.1|WP_041207033.1|2820073_2820601_-|molybdenum-cofactor-biosynthesis-protein-B
MAPKHNEFIPLKIAVLTVSDSRTAADDSSGDYLVSALTEAGHQLTDRALCPDNLFRIRAQVSDWIVDDGVQVVLINGGTGFNEQNRVPEAVGVLFERTVQGFGEMFRQLSFAEIKGSAMQSRALAGLANRTLICCLPGSTGACQLGWEQLIRDQLDARTRPCNFVAHLSTSAIPA
>NZ_CP007567.1|WP_005325513.1|2820822_2821413_-|cytochrome-c3-family-protein
MKLPGFIQRLWTTFKSPSKAALWVLLLMGFFGGVIFWGGFNTAMEASNTEKFCTGCHEMKDNVFVEYRDTIHYANRSGVRASCPDCHVPHEWTYKIIRKVQASKELWGMITGKVDTREKFESHRREMAEREWQRMKDTDSRECRNCHNFEYMDFSLQGKRGAQMHSTSLASGESTCIDCHKGIAHQLPDMKGVEGF
>NZ_CP007567.1|WP_041206124.1|2821424_2821880_-|nitrate-reductase-cytochrome-c-type-subunit
MKKLIGAMLACLMAGSLMAATPEITNSTGGIKSERGSTDLVTDADAAPMKNYRKDGDLYDRQYMHQPPLIPHDTRNYEVDNKVNKCLACHSFKNASKMKAPKISPTHFETRDGMTLGEVSPRRYFCLQCHVPQADAKPLVENTFKPVEALN
>NZ_CP007567.1|WP_041206126.1|2821879_2822755_-|quinol-dehydrogenase-ferredoxin-subunit-NapH
MSRYPGAEASARLGWWRAHRFLLLRRLCQFGVLGLFLLGPLAGVWILKGNLSSSLLLETVPLTDPLTLLQSVAAGHWPITTLWLGAGLVLLGYWLVGGRVFCSWVCPVNLVTDAAAWLRARLGLKGNGQFNRNTRYWLLAMVLVAPAITGVLVWELVNPVSLAMRGLLFGMGAGWGLLVALFLFDLFVVERGWCGHLCPVGAFYALVNRVGFIKISAKGRERCSNCMDCYAVCPERPILRGPVHGARRGHGPLIVAQECTNCGRCIDVCAEQVFEITTGFAVKAEKTSENK
>NZ_CP007567.1|WP_005325518.1|2822751_2823486_-|ferredoxin-type-protein-NapG
MSRSRRQFLADLAKGACSVGLLGVGLGSVARQQVQAVPAQALRPPAALGEADFLGACVRCGLCVEACPYDTLKLARLLDPVTTGTPYFEARSVPCEMCDDIPCVVACPSGALDQGMTDIDQARMGVAVLIDHETCLNYLGLRCDVCYRVCPLIDKAITLELQRNPRTGKHAMFLPTVHSDICTGCGKCEHACVLETAAIKVVPRQLAKGELGHHYRLGWEEKAKAGKSLIGERLTLPTRKPEGL
>NZ_CP007567.1|WP_041206127.1|2823499_2825989_-|nitrate-reductase-catalytic-subunit-NapA
MKLSRRDFMKANAVAAAAAVAGVSAPTLAANLITSTDKTAITWDKAPCRFCGTGCSVLVGSQAGRVVATQGDPDAPVNRGLNCIKGYFLSKIMYGEDRLTQPMLRMTNGKFDKNGDFAPISWDQAFDIMAEKFKATLKEKGPTAVGMFGSGQWTVWEGYAAAKLMKAGLRTNNLDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMHPILWSRMSDRRLSNPDVQVHVLSTFEHRSFELADNGMVFTPQTDLAILNYIANYIIQNDKVNWDFVNKHTQFRKGVTDIGYGLRPTHPTQQKAKNPDSGDSTPMSFDDFAKFVADYDVESVAKLSGVSKDKLEKLAQIYADPDKKVVSYWTMGFNQHTRGVWANNLCYNIHLLTGKISTPGSGPFSLTGQPSACGTTREVGTFAHRLPADMVVTDPKHRAIAEKIWKLPEGTIPEQVGYHAVLQNRMLKDGKLNAYWVMCNNNMQAGPNMNEEGLPGYRNPANFIVVSDPYPTVTAQAADLILPTAMWVEKEGAYGNAERRTQFWHQQVKAPEGAKSDLWQLMEFSKRFTVEEVWPAELIAKMPEVKGKTLFEVLYANGQVNQFPKEQSKGALNDEAEHFGFYVQKGLFEEYASFGRGHGHDLAPFDQYHEARGLRWPVVDGKETLWRYREGFDPYVKAGEGVKFYGKPDGKAVIFALPYEPAAEAPDKEYDMWLSTGRVLEHWHTGTMTRRVPELYRAFPDAVLFMHPEDAKARGVRRGEEVIVSSRRGEVKTRVETRGRNRPPKGLVFMPFFDAIQLVNKLTLDATDPLSKQTDYKKCAVKVMKA
>NZ_CP007567.1|WP_041204444.1|2826115_2826382_-|chaperone-NapD
MTREEFHVSSLVVLTQPPLRHRLAEQIAALDGAEIHAVSDEGKLVVTLEGPSQRPIMAAIDAINAMPGVLSAALIYHQFDEVEAEGRE
>NZ_CP007567.1|WP_041206129.1|2826414_2826924_-|ferredoxin-type-protein-NapF
MPDGVNLSRRSLFRGRLSAPRPEVQLPWSVSWADFVADCTRCGDCLTACPEQILIKGDGGFPTVDFQRGECTFCGECVSACQVPVFRPTTQTPWDYVAHIEAGCLASAQVFCQRCQDSCEQQAIRFSPQLGRVPTPSIHTESCNGCGACVADCPVGSIRVGAPHEGSAR

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Crispr_ID: NZ_CP007567_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_8

2894398-2894502

Orphan

Consensus_repeat	Method
CGATCAGAGCAGCGCGGCCACTTCGTCGGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_8

>merge|NZ_CP007567|8|2894398-2894502|CRISPRCasFinder
CGATCAGAGCAGCGCGGCCACTTCGTCGGAGGTGACACCGTTGTGGTGCACCTCCTATCGCTAGTTGCTGCTGACGATCAGAGCAGCGCGGCCACTTCGTCGGAG

>NZ_CP007567|8|8|2894398-2894502|CRISPRCasFinder
CGATCAGAGCAGCGCGGCCACTTCGTCGGAG	GTGACACCGTTGTGGTGCACCTCCTATCGCTAGTTGCTGCTGA
CGATCAGAGCAGCGCGGCCACTTCGTCGGAG

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_041206155.1\|2905141_2905588_+\|C40-family-peptidase	unknown	unknown	gnl\|CDD\|236773
NZ_CP007567.1\|WP_041206154.1\|2891219_2892434_+\|ROK-family-protein	unknown	unknown	gnl\|CDD\|366120
NZ_CP007567.1\|WP_005325703.1\|2901297_2902836_+\|inactive-transglutaminase-family-protein	unknown	unknown	gnl\|CDD\|379600
NZ_CP007567.1\|WP_005325686.1\|2890069_2891215_+\|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl\|CDD\|183010
NZ_CP007567.1\|WP_005325688.1\|2892502_2894128_-\|phosphoethanolamine--lipid-A-transferase	unknown	unknown	gnl\|CDD\|183224
NZ_CP007567.1\|WP_005325675.1\|2881455_2881956_-\|DUF4442-domain-containing-protein	unknown	unknown	gnl\|CDD\|373120
NZ_CP007567.1\|WP_041206153.1\|2884747_2887411_-\|carbohydate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|119337
NZ_CP007567.1\|WP_005325685.1\|2889259_2890060_+\|glucosamine-6-phosphate-deaminase	unknown	unknown	gnl\|CDD\|179028
NZ_CP007567.1\|WP_005325692.1\|2895283_2897062_-\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NZ_CP007567.1\|WP_005325705.1\|2902839_2903805_+\|alpha-L-glutamate-ligase-like-protein	unknown	unknown	gnl\|CDD\|274070
NZ_CP007567.1\|WP_171269495.1\|2900535_2901294_+\|ATP-dependent-zinc-protease	unknown	unknown	gnl\|CDD\|226553
NZ_CP007567.1\|WP_041206156.1\|2905671_2905965_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_005325699.1\|2899475_2900453_+\|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB	unknown	unknown	gnl\|CDD\|237898
NZ_CP007567.1\|WP_005325679.1\|2882746_2884408_-\|glutamine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235424
NZ_CP007567.1\|WP_005325707.1\|2904109_2905024_+\|hydrogen-peroxide-inducible-genes-activator	unknown	unknown	gnl\|CDD\|176103
NZ_CP007567.1\|WP_005325694.1\|2897494_2898355_+\|DUF72-domain-containing-protein	unknown	unknown	gnl\|CDD\|182366
NZ_CP007567.1\|WP_005325683.1\|2887533_2888988_-\|PTS-transporter-subunit-EIIC	unknown	unknown	gnl\|CDD\|273920
NZ_CP007567.1\|WP_005325697.1\|2898738_2899479_+\|carboxy-S-adenosyl-L-methionine-synthase-CmoA	unknown	unknown	gnl\|CDD\|273244
NZ_CP007567.1\|WP_005325673.1\|2880884_2881409_+\|flavodoxin-FldA	unknown	unknown	gnl\|CDD\|236439
NZ_CP007567.1\|WP_005325677.1\|2882200_2882629_+\|ferric-iron-uptake-transcriptional-regulator	unknown	unknown	gnl\|CDD\|236527

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_041206155.1\|2905141_2905588_+\|C40-family-peptidase	gnl\|CDD\|236773	PRK10838, spr, bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase.	3.27701e-42
NZ_CP007567.1\|WP_041206154.1\|2891219_2892434_+\|ROK-family-protein	gnl\|CDD\|366120	pfam00480, ROK, ROK family.	1.2933e-71
NZ_CP007567.1\|WP_005325703.1\|2901297_2902836_+\|inactive-transglutaminase-family-protein	gnl\|CDD\|379600	pfam14402, 7TM_transglut, 7 transmembrane helices usually fused to an inactive transglutaminase. A family of seven transmembrane helices fused to an inactive transglutaminase domain. The transglutaminase domain is predicted to be extracellularly located. Members of this family are associated in gene neighborhoods with a pepsin-like peptidase and an ATP-grasp of the RimK-family. The ATP-grasp is predicted to modify the 7TM protein or a cofactor that interacts with it.	7.905e-151
NZ_CP007567.1\|WP_005325686.1\|2890069_2891215_+\|N-acetylglucosamine-6-phosphate-deacetylase	gnl\|CDD\|183010	PRK11170, nagA, N-acetylglucosamine-6-phosphate deacetylase; Provisional.	0
NZ_CP007567.1\|WP_005325688.1\|2892502_2894128_-\|phosphoethanolamine--lipid-A-transferase	gnl\|CDD\|183224	PRK11598, PRK11598, putative metal dependent hydrolase; Provisional.	0
NZ_CP007567.1\|WP_005325675.1\|2881455_2881956_-\|DUF4442-domain-containing-protein	gnl\|CDD\|373120	pfam14539, DUF4442, Domain of unknown function (DUF4442). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 139 and 165 amino acids in length. There is a conserved PYF sequence motif. There is a single completely conserved residue N that may be functionally important.	1.86327e-28
NZ_CP007567.1\|WP_041206153.1\|2884747_2887411_-\|carbohydate-binding-domain-containing-protein	gnl\|CDD\|119337	cd06569, GH20_Sm-chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	0
NZ_CP007567.1\|WP_005325685.1\|2889259_2890060_+\|glucosamine-6-phosphate-deaminase	gnl\|CDD\|179028	PRK00443, nagB, glucosamine-6-phosphate deaminase; Provisional.	1.38008e-175
NZ_CP007567.1\|WP_005325692.1\|2895283_2897062_-\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NZ_CP007567.1\|WP_005325705.1\|2902839_2903805_+\|alpha-L-glutamate-ligase-like-protein	gnl\|CDD\|274070	TIGR02291, conserved_protein_of_unknown_function, alpha-L-glutamate ligase-related protein. Members of this protein family contain a region of homology to the RimK family of alpha-L-glutamate ligases (TIGR00768), various members of which modify the Glu-Glu C-terminus of ribosomal protein S6, or tetrahydromethanopterin, or a form of coenzyme F420 derivative. Members of this family are found so far in various Vibrio and Pseudomonas species and some other gamma and beta Proteobacteria. The function is unknown.	2.73076e-160
NZ_CP007567.1\|WP_171269495.1\|2900535_2901294_+\|ATP-dependent-zinc-protease	gnl\|CDD\|226553	COG4067, COG4067, Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones].	1.56896e-49
NZ_CP007567.1\|WP_005325699.1\|2899475_2900453_+\|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB	gnl\|CDD\|237898	PRK15068, PRK15068, tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB.	0
NZ_CP007567.1\|WP_005325679.1\|2882746_2884408_-\|glutamine--tRNA-ligase	gnl\|CDD\|235424	PRK05347, PRK05347, glutaminyl-tRNA synthetase; Provisional.	0
NZ_CP007567.1\|WP_005325707.1\|2904109_2905024_+\|hydrogen-peroxide-inducible-genes-activator	gnl\|CDD\|176103	cd08411, PBP2_OxyR, The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily. OxyR senses hydrogen peroxide and is activated through the formation of an intramolecular disulfide bond. The OxyR activation induces the transcription of genes necessary for the bacterial defense against oxidative stress. The OxyR of LysR-type transcriptional regulator family is composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The C-terminal domain also contains the redox-active cysteines that mediate the redox-dependent conformational switch. Thus, the interaction between the OxyR-tetramer and DNA is notably different between the oxidized and reduced forms. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.31363e-79
NZ_CP007567.1\|WP_005325694.1\|2897494_2898355_+\|DUF72-domain-containing-protein	gnl\|CDD\|182366	PRK10302, PRK10302, hypothetical protein; Provisional.	3.15167e-102
NZ_CP007567.1\|WP_005325683.1\|2887533_2888988_-\|PTS-transporter-subunit-EIIC	gnl\|CDD\|273920	TIGR01998, N-acetylglucosamine_and_glucose_PTS, PTS system, N-acetylglucosamine-specific IIBC component. This model represents the combined B and C domains of the PTS transport system enzyme II specific for N-acetylglucosamine transport. Many of the genes in this family also include an A domain as part of the same polypeptide and thus should be given the name "PTS system, N-acetylglucosamine-specific IIABC component". This family is most closely related to the glucose-specific PTS enzymes. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NZ_CP007567.1\|WP_005325697.1\|2898738_2899479_+\|carboxy-S-adenosyl-L-methionine-synthase-CmoA	gnl\|CDD\|273244	TIGR00740, tRNA_cmo5U34-methyltransferase, tRNA (cmo5U34)-methyltransferase. This tRNA methyltransferase is involved, together with cmoB, in preparing the uridine-5-oxyacetic acid (cmo5U) at position 34. [Unknown function, Enzymes of unknown specificity].	9.911e-133
NZ_CP007567.1\|WP_005325673.1\|2880884_2881409_+\|flavodoxin-FldA	gnl\|CDD\|236439	PRK09267, PRK09267, flavodoxin FldA; Validated.	2.1061e-106
NZ_CP007567.1\|WP_005325677.1\|2882200_2882629_+\|ferric-iron-uptake-transcriptional-regulator	gnl\|CDD\|236527	PRK09462, fur, ferric uptake regulator; Provisional.	1.22597e-102

>NZ_CP007567.1|WP_005325688.1|2892502_2894128_-|phosphoethanolamine--lipid-A-transferase
MRLTLGVMKVNLLLVLLFALVFNWPIFLHFYRILTALEHVKAGFALSIPLVLIAALNAVFLPFTFRYLLKPFFILLIMTASLVSYAMLKYGIIFDVGMVQNILETNSGEATSYLNASVVLWFLLTAVLPVLGLLWIKVEYPTPWYKGLGLRLGSIALSLLFLVGVAALYYQDYASVGRNNHSIVKEIVPSNYVRGLYRYARDILFATPVPYEPIGTDARVVAKSDKPTLMFLVVGETARSQNYSLNGYQKQTNGFTMKEPDLVSFRDVRSCGTATAVSVPCMFSNLTRREYDETLAKSRDGLLDVLQHAGVSVLWKENDGGCKGVCNHVPTLEIEPKTFPEYCEGDSCYDEVLLQGLDQQIAGMKGKQGSKLVAFHLMGSHGPTYYRRYPAADRVFLPDCPRSDIENCSNEELVNTYDNTIRYTDKVLSQLIDKLKTLESQYNVGLVYLSDHGESLGAMGLYLHGTPYKFAPDDQTRVPLLTWFSPQLQRDRQLDQDCLRQEAGSKRFSHDNLFHSMLGIMDVQTQAYDGKLDLFKPCRAG
>NZ_CP007567.1|WP_041206154.1|2891219_2892434_+|ROK-family-protein
MTGGQIANVDLIKQVNSAVVYRLIDLQGPISRVKIAELSQLAPASVTKITRQLIEHGLIRETSPQASTGGRRAISLTTIKHRFQFVSAKLGRGYLQLSLYDLDGKELDQHITQVTEIEQQPVVDMLLREIGAFIDANTERSRNLISIALTMPGLVNPESGMVIYTPTYQIRNLGLAKLLEHHFNLPCYVGNDTRSLALAEHFFGESRDCMDSILVSVHQGTGSGIITKGQVFLGHNRNVGEIGHIQVEPLGKRCHCGNFGCLETIASNEAIVDKVKELISRGHLSSLQEKHITIQEVCKAAMAGDELARSVIENVGEHLGRAIAITVNLFNPQKVLIAGEITAAEEILIPAIRRCVEHQSLPSFHRGLPIVKARFQNQPTIGGFALVKRSLLEGDLLQIIMEQK
>NZ_CP007567.1|WP_005325686.1|2890069_2891215_+|N-acetylglucosamine-6-phosphate-deacetylase
MYALTNCTLYTGSCVLTGHGVLIEGDKIVAISHLAELPAGIERIDLKGANLSAGFIDVQLNGCGGVMFNGHITTQTLATMQAANLKSGTTSFLPTLITSPDADMKLAVAVTRDYMAAHPNEVLGVHLEGPYTNLKRKGIHPAEQIRQPVDEMIDFFCANSDAIAKITLAPERNKPEHIRRLVEAGILVSAGHTAASYDQAMAGFDNGMRFATHLYNAMTPTLNGREPGVVGAIYDRKDVYAGVIVDGHHVHWANVRLAHRILGEKLVLVTDATAAAGAPEGFEQFDFCGATVYFRDGQCVDENGTLGGSALTMIEGVENLVKQVGLPLDEALRMATLYPARAIGWDSRLGSIQVGKIANLTVFDQAFTVCGTVVNGHYTTQ
>NZ_CP007567.1|WP_005325685.1|2889259_2890060_+|glucosamine-6-phosphate-deaminase
MRLIPLKSASQVGLWSARYIVDRINAFKPTSDRPFVLGLPTGGTPLTTYKRLIELHQAGEVSFQNVVTFNMDEYVGLPKEHPESYHSFMHNNFFNQVDIRPENINILNGNAEDLVAECKRYEDKIKSYGKINLFMGGVGNDGHIAFNEPASSLASRTRVKTLTEDTRIANSRFFGGDMEQVPKLALTVGVGTLMDAEEIMILVTGHAKALALQAAVEGCVNHMWTISTLQLHPKGMMVCDEPSTMELKVKTVRYFQQLEAANIDRL
>NZ_CP007567.1|WP_005325683.1|2887533_2888988_-|PTS-transporter-subunit-EIIC
MNILGYLQKIGRALMVPVAVLPAAAILMGIGYWIDPNGWGGESALAAFLIKAGAAIIDKMAILFAVGVAYGMSKDKDGSAALAGLVGYLVVTTLLSPGAVSQIQQIPLDQVPAAFGKIENQFIGILTGVIAAELYNRFSGVELHKALAFFSGRRLVPIVTSVVMIVVSFILMAVWPIIYGGLVSFGESIVSMGSTGAGIYAFFNRLLIPVGLHHALNSVFWFDVAGINDIPNFLGGQSSIDAGKAVVGVTGMYQAGFFPIMMFGLPGAALAIYHSAKKENKEKVASIMIAAAFAAFFTGVTEPLEFSFMFVAPVLYVIHALLTGLSVFIAASMHWISGFGFSAGFVDMFIQSRNPLATQWYMLLVQGLVFFGLYYAIFRAVIVKFNLKTPGREDDEAVPVQAQTTDRTELARQYLEVLGGQDNLVTIDACITRLRLTLKDRSIVDERKLKALGAAGVVKLGEQNLQVILGPLAEIIAGEMKALR
>NZ_CP007567.1|WP_041206153.1|2884747_2887411_-|carbohydate-binding-domain-containing-protein
MNLKHSLLAIAMSTVFVSQVQAADAAKQAVVDSLASNLVVKYEVVTNDGAGAGLDCQALGSEWASCGVAKLHLTNTGADVTSKDWSIYVSSIRRIQRVDNDQFTITHLTGDLYRLTPTEKFQGFAKDATVEVPLVVEYWVLFESDIMPNWYVASEGAEPKVLASMSNIDDATTYEKPMPADGWKRTKDDNNILMNSETRFAANQTSTLLPAGKIDDQILPSPMKQVVKAGPQVDFSTIKLNALDLPSDRAEALKAQLTKLGVTLSDTGYPVTIKLGSKLKQAEGYDMTIGAKGTVVQGHDIDGAFWGAQSLISLLGVDDKLVSQMSIEDAPRFEYRGMQTDVARHFRSPETMKKLVDQMSAMKLNVLHLGLTNDEGWRIEIPGLPELTDVGSQRCHDESETKCLMPQLGSGPTSDNQGSGFYSKADYIDLVRYAKARGVTVIPEINMPAHARAAVVSMEAHYKRLLAEGKEAEANQFRLTDPDDTSNVTSVQFYDKMSFINPCQPGAATFVAKVMDEVAQMHQAAGQPLTAWHYGGDEAKNIMQGGGYQDPAVTKKEELVAWKGNVDSSKQDKPFGKSPLCQKMIDDGKLKDVAELPVHFAKEVSEMVKGHGFSTLQAWEDGLKYATDASVFATDKTRVNFWETLYWGGFNEAMKWAHKGYDVVLSNPDYLYFDFPNEVHPAERGYYWATRFNDTRKVFAFAPENLPQNAETSVDRDGNAFVAKGDQDPVKFKGISGQQWSETVRTDAQYEYMVYPRIFSVAERAWHKGGFELDYVKGREFSGTTKHVNKATLNKEWNQFANLLGQRVLPKLDQAGVEYRLSVPGAKVVNGKLEANVDLPGLPIQYSLDGTNWTAYDAAAKPSVTGKVWLRTTSFDGKRTSRVTELN
>NZ_CP007567.1|WP_005325679.1|2882746_2884408_-|glutamine--tRNA-ligase
MSEASSPTNFIRQIIDEDLASGKHKSVHTRFPPEPNGYLHIGHAKSICLNFGIARDYQGQCNLRFDDTNPAKEDIEFVESIKQDVQWLGFQWSGEICYSSDYFDKLHGYAIELIEKGLAYVDELSPEQMREYRGTLTAPGKNSPFRDRSVEENLALFAKMKSGEMAEGSACLRAKIDMASPFMVMRDPVIYRIKFAHHHQTGDKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNISIDCHPRQYEFSRLNLEYTVMSKRKLNLLVTEGHVSGWDDPRMLTVSGLRRRGYTPASIREFCQRIGVTKQDNIVEMSMLEACIRDDLNENAPRAMAVLHPVKVVIENLAADEVLTAPAHPSNAEMGTRELNFTREIFIDEADFKEEANKQFKRLVLGKEVRLRNAYVIKAERVEKDADGKVTCIYCSYDPETLGKDPADGRKVKGVIHWVSATHSLPAEIRLYDRLFKMPNPGAEDDFEAALNPDSLVIIAGARVEASLKDAKPEFAYQFEREGYFCADNKLSSPEHLVFNRTVALRDVWGKAEA
>NZ_CP007567.1|WP_005325677.1|2882200_2882629_+|ferric-iron-uptake-transcriptional-regulator
MADNNQALKKAGLKITLPRVKILEILQQPDCQHTSAEDLYKRLIDQGEEIGLATVYRVLNQFDDAGIVTRHHFEGGKSVFELATQEHHDHLVCLDCGKVIEFSDEVIEQRQRDIAKHHNIRLTNHSLYLYGHCVNGDCKHDE
>NZ_CP007567.1|WP_005325675.1|2881455_2881956_-|DUF4442-domain-containing-protein
MDWLFDNAAWVRHALNAWPPFWGAGIKIETLSPDFRFCRVTLKSRWWNKNANRTQFGGSMFAMTDPIYPLMLMGHFKNRYYVWDKAGSINFIKPGKGMLVAEFNLTDAKLASIVAATEGGNKHFPEFEVQVQDKRGELVAQVRRTLYVKPKPEHRTPGQAASTMKE
>NZ_CP007567.1|WP_005325673.1|2880884_2881409_+|flavodoxin-FldA
MASVGLFFGSDTGNTEAVAKMIQKELGKQLIEVRDIAKSSKADIDSFDLLMFGIPTWYYGEAQADWDDFFPELEEIDFNNKLVAIFGCGDQEDYSEYFLDAMGTLRDIVEAKGAIIIGHWPTASYEFEASKALVDDKHFVGLGIDEDRQPELTAERVKGWCKQLHEEMCLSELE
>NZ_CP007567.1|WP_005325692.1|2895283_2897062_-|aspartate--tRNA-ligase
MRSIYCGQVNEAHAGQTITLCGWVHRRRDLGGLIFIDMRDREGIVQVFFDPDKPDAFALASELRGEFCIQVTGVVRTRPDSQRNSDMATGAIEVFAHELTIINRAEPLPLDFNQVNSEEISLKYRYLDLRRPEMAKYLKTRAKASAFVRRFMDEQGFLDIETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMTAPQVREIMEEMIRKLWLHILNVDLGDFPIMTFDEAMRRFGSDKPDLRLPMELVDVADLLTAVEFAVFAGPANDPKGRVAALKVPGGAELSRKQIDEYTKFVGIYGAKGLAWMKVNEAANGIEGVQSPVAKFLTDEIVREILARTGAADGDILFFGADSKKVVCDAMGALRLKVGRDLGLVENVWKPLWVIDFPMFEEDGEGGLAAMHHPFTAPSNLGPSELKANPLGAYANAYDMVINGYEVGGGSVRIHNSEMQSTVFDILGITPDEQRLKFGFLLDALKYGTPPHAGLAFGLDRLSMLLTGTDNIRDVIAFPKTTAAACLMTDAPSFANQAQLTELAIATVAKADAKADA
>NZ_CP007567.1|WP_005325694.1|2897494_2898355_+|DUF72-domain-containing-protein
MSLYLGLPQWSHPAWPGQLLGVGARPAEHLAHYARVFNTVEGNTTFYASPTPDTVRRWADAVPPQFRFSFKFPKEISHQSDLVSAGKQVADFITLLGPLHGQLGLLKLQLPARFGPAGLPRLAAFFEGLPPDFTYALEVRHPDFFAKGEAERALNRLLMDKGINRIMLDSRPLFSVPASLAAKNAALVDAQGKKPRLPVHLLATANSPVVRLIGLPHPEDNHPFLPSWLPRWQQWLAEGKNLYLFIHTADNARAPELARQVSRLLGQEMAPWPGENDRARQGLLPF
>NZ_CP007567.1|WP_005325697.1|2898738_2899479_+|carboxy-S-adenosyl-L-methionine-synthase-CmoA
MHDQIFAAPIAQLGDFCFDEQVVDVFPDMIQRSVPGYSNIISAIGMMAARYAQPQSRLYDLGCSLGAATQAMRRHVNQPGCQITAVDLSHPMIERARAHLSGFKSEVPVELVEADICDIAIENASVVVLNFTLQFVAPEKRAALIQRIHDGLRPGGILILSEKFRFEDEQVNALLIDLHLDFKRANGYSELEISQKRTALENVMRTDSLEIHRARLRDAGFTHQDLWFQCFNFGSMIAIKSSDAQP
>NZ_CP007567.1|WP_005325699.1|2899475_2900453_+|tRNA-5-methoxyuridine(34)/uridine-5-oxyacetic-acid(34)-synthase-CmoB
MIDFANFYQLIAKNRLSHWLHTLPAQLHAWQHDNLHGDLPRWNRALNKLPQVAPGNVELKSRVEVGGMDSLNEGERKKTESLLRQFMPWRKGPFTVHGIHIDTEWRSDWKWERVLPHISPLAGRYVLDVGCGSGYHLWRMVGEGAKLAVGIDPSPLFLCQFEAIRHFAGNDQRAHLLPLGIQELPELRAFDTVFSMGVLYHRKSPIEHIEQLRNQLKDDGELVLETLVIDGGVNDVLVPTDRYGKMRNVWFIPSSAALKLWVERCGFSDVRIVDENMTSTDEQRRTDWMINESLSDYLDPDDPALTVEGYPAPKRAVLIARKAKD
>NZ_CP007567.1|WP_171269495.1|2900535_2901294_+|ATP-dependent-zinc-protease
MTLLSLLSLGGCVSMEKAPPAPTLTLAELRNEITLSEQRLQTSMEQQQKQYVQQQHLLVQLNTDVTNMKESVKKVDSKLATLPPEPPKPMAIPTEKCPAPSQGHTVDGKLLVGEAEWIWVDAANDAFQARVDTGATTSSISAQEITIFERNGKNWVRFFLSHQEMDDKIQIEAPLVRHVRVRQASADDLDRRPVVRLTVRIGDMTEKAEFTLKDRSDMTFPVLLGREFLKDIAVVDVAREYIQPKPKLKDVK
>NZ_CP007567.1|WP_005325703.1|2901297_2902836_+|inactive-transglutaminase-family-protein
MVSRKPFYLLVALLFIVGLGMTFYHHVALDVPLTPGEKRQIWSIEAKLEFEATGEPVIASLAIPGTQPGFTLMNENAASPGYGLSFVEKDGDARAEWSIRTASGRQELYYRVDMMADAHAKPAANPLPPAIEKQIESEPYATAMKQILERAQERSADGYTLTREIIKEIEKQEQNAELLKSHKSRASLIAELLNNAEVPARVVHALSLEDGRRRQELVDYLQVFNSPTDYKLFNPQTGEQGQPGNLLLWEYNSGALLDVTGGHNSRVTFSMIEQEQPVNVALAQKFEKSEMMNFSIHSLPLEEQALFKGLLLIPIGVLMVVFLRVLVGIKTSGTFMPVLIAVAFIQTSLVTGLIGFLLIVGTGLVIRSYLSRLNLLLVARISAIIIMVISMIGIFSAFAFKLGLTDGMKITFFPMIILSWTIERMSILWEEEGPKEVFRQGGGSLLVAVIAYLAMDNELIRHLTFNFLGLQLVLMATVLVMGNYTGYKLSELKRFKPLVDEMKSGATPGKDK
>NZ_CP007567.1|WP_005325705.1|2902839_2903805_+|alpha-L-glutamate-ligase-like-protein
MWFWQKYTSPWSLSQAGILGMNKRNHSYISRYNPRRLYPLVDDKLKTKRIALDAGVTVPELIGTIREQHDVTRITELVKDWPGFCIKPARGSGGKGILVILRQEEGSFYKPNGSASTGQDLERHVSNILAGLYSLGGKPDVALVEGLINFDDVFDGYSFEGVPDARVIIFKGFPVMAMMRLSTAASDGKANLHQGAVGVGLCLRTGRALRAVQFGNPLRHHPDTGLDLYDLKVPHWDTLLTLAASCYEMSGLGYIGTDMVLDKFRGPMLLELNARPGLAIQIANGRGLVPNLKTIEKLGQVKMNVEQRVNFAKDHFGIFDE
>NZ_CP007567.1|WP_005325707.1|2904109_2905024_+|hydrogen-peroxide-inducible-genes-activator
MQRWPSLKQLQYLVALDEHKNFNRAAKACHVSQSTLSTGIQTLEDMMNLQLVERDHKSFIMTPVGMEIVARARNLLSDARDLMELSQQQGGVMHGTVRLGCIPTIAPFLLSKLLQVCGKAYPELELLLREDTTTNLLKQLEQGQLDLLILALPVEIGGFHCKTVGQDPFHMVMPSHMAAGLHMPFDYKELPNQSIFLLEREHCLTEHAVSACRLRDKSKINPFAATSLHTLVQMVGAGLGTTFLPQMAIDAGILENSDLVAIPLPGEKPYREIGLVWRPSTTRVQTFYKIAELLTPLITPKAAD
>NZ_CP007567.1|WP_041206155.1|2905141_2905588_+|C40-family-peptidase
MFRTLLPPLLALFVIACSSTPEPPPARQASAFDGFYQQWRGVPYRMGGTNRAGLDCSAFTQLAYQQVLGFTLPRTTESQASLGRPVDRYRLQHGDLVFFKTGWQQYHVGVYTGSGEFIHASTSKGVIRSRLDNVYWNSRYWQARRLTQ
>NZ_CP007567.1|WP_041206156.1|2905671_2905965_-|hypothetical-protein
MTRELHSLLARLDDVIERMPDSFNTYEFAQKLALQHQREYFAAGHSLAEQDKNLLRLLHEKIALALASHDGVIEGALLPCVTPWGERATSPRWHRKH

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Crispr_ID: NZ_CP007567_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_9

3337673-3337759

Orphan

Consensus_repeat	Method
CGCCAACGCCTCCTGTCCCTTCCTTCTTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_9

>merge|NZ_CP007567|9|3337673-3337759|CRISPRCasFinder
CGCCAACGCCTCCTGTCCCTTCCTTCTTTCGCTGGTCCTGAACGCCCGGAGCCGGAGCGCCAACGCCTCCTTTCCCTTCCTTCTTTC

>NZ_CP007567|9|9|3337673-3337759|CRISPRCasFinder
CGCCAACGCCTCCTGTCCCTTCCTTCTTTC	GCTGGTCCTGAACGCCCGGAGCCGGAG
CGCCAACGCCTCCTTTCCCTTCCTTCTTTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_005328600.1\|3336918_3337656_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|376350
NZ_CP007567.1\|WP_041206313.1\|3337945_3339307_+\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|377028
NZ_CP007567.1\|WP_041206314.1\|3339363_3342471_-\|tetrathionate-reductase-subunit-TtrA	unknown	unknown	gnl\|CDD\|237883
NZ_CP007567.1\|WP_005326894.1\|3346558_3347170_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|226932
NZ_CP007567.1\|WP_041206312.1\|3333511_3334465_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NZ_CP007567.1\|WP_005328605.1\|3330711_3332559_-\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NZ_CP007567.1\|WP_005326891.1\|3347310_3348051_+\|dipeptidase-PepE	unknown	unknown	gnl\|CDD\|179990
NZ_CP007567.1\|WP_041206315.1\|3343566_3344355_-\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|184955
NZ_CP007567.1\|WP_005328602.1\|3334669_3335758_+\|ketoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|237245
NZ_CP007567.1\|WP_005326882.1\|3350797_3354766_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|236989
NZ_CP007567.1\|WP_041205051.1\|3354883_3356221_+\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP007567.1\|WP_005328612.1\|3328566_3329043_+\|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|234860
NZ_CP007567.1\|WP_005328610.1\|3329954_3330212_-\|DUF1272-domain-containing-protein	unknown	unknown	gnl\|CDD\|226334
NZ_CP007567.1\|WP_005328595.1\|3342470_3343577_-\|polysulfide-reductase-NrfD	unknown	unknown	gnl\|CDD\|184954
NZ_CP007567.1\|WP_005330481.1\|3356453_3357527_-\|alanine-racemase	unknown	unknown	gnl\|CDD\|143500
NZ_CP007567.1\|WP_005328608.1\|3330258_3330588_-\|DHCW-motif-cupin-fold-protein	unknown	unknown	gnl\|CDD\|380395
NZ_CP007567.1\|WP_041206311.1\|3332771_3333383_-\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NZ_CP007567.1\|WP_005328601.1\|3336455_3336731_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_041206310.1\|3329390_3329765_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380395
NZ_CP007567.1\|WP_005326888.1\|3348153_3349545_+\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_005328600.1\|3336918_3337656_+\|EAL-domain-containing-protein	gnl\|CDD\|376350	pfam00563, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.	1.49464e-39
NZ_CP007567.1\|WP_041206313.1\|3337945_3339307_+\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	4.73658e-08
NZ_CP007567.1\|WP_041206314.1\|3339363_3342471_-\|tetrathionate-reductase-subunit-TtrA	gnl\|CDD\|237883	PRK14991, PRK14991, tetrathionate reductase subunit TtrA.	0
NZ_CP007567.1\|WP_005326894.1\|3346558_3347170_+\|response-regulator-transcription-factor	gnl\|CDD\|226932	COG4566, TtrR, Response regulator [Signal transduction mechanisms].	2.99632e-67
NZ_CP007567.1\|WP_041206312.1\|3333511_3334465_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.07884e-55
NZ_CP007567.1\|WP_005328605.1\|3330711_3332559_-\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	2.8066e-87
NZ_CP007567.1\|WP_005326891.1\|3347310_3348051_+\|dipeptidase-PepE	gnl\|CDD\|179990	PRK05282, PRK05282, dipeptidase PepE.	5.88577e-119
NZ_CP007567.1\|WP_005330481.1\|3356453_3357527_-\|alanine-racemase	gnl\|CDD\|143500	cd06827, PLPDE_III_AR_proteobact, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases. This subfamily is composed mainly of proteobacterial alanine racemases (EC 5.1.1.1), fold type III PLP-dependent enzymes that catalyze the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. hese proteins are similar to other bacterial ARs and are fold type III PLP-dependent enzymes containing contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Homodimer formation and the presence of the PLP cofactor are required for catalytic activity.	0
NZ_CP007567.1\|WP_005328602.1\|3334669_3335758_+\|ketoacyl-ACP-synthase-III	gnl\|CDD\|237245	PRK12879, PRK12879, 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed.	1.69174e-174
NZ_CP007567.1\|WP_005326882.1\|3350797_3354766_+\|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|236989	PRK11809, putA, trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed.	0
NZ_CP007567.1\|WP_041205051.1\|3354883_3356221_+\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	1.77276e-31
NZ_CP007567.1\|WP_005328612.1\|3328566_3329043_+\|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl\|CDD\|234860	PRK00901, PRK00901, methylated-DNA--protein-cysteine methyltransferase; Provisional.	1.6317e-63
NZ_CP007567.1\|WP_005328610.1\|3329954_3330212_-\|DUF1272-domain-containing-protein	gnl\|CDD\|226334	COG3813, COG3813, Uncharacterized protein conserved in bacteria [Function unknown].	9.51334e-32
NZ_CP007567.1\|WP_005328595.1\|3342470_3343577_-\|polysulfide-reductase-NrfD	gnl\|CDD\|184954	PRK14992, PRK14992, tetrathionate reductase subunit TtrC.	2.09224e-51
NZ_CP007567.1\|WP_005328608.1\|3330258_3330588_-\|DHCW-motif-cupin-fold-protein	gnl\|CDD\|380395	cd06990, cupin_DUF861, domain of unknown function DUF 861, cupin domain. This family contains proteins which seem to be specific to bacteria and some fungi. The function of this family is unknown but contains a cupin domain without a metal binding site. Cupins are a functionally diverse superfamily originally discovered based on the highly conserved motif found in germin and germin-like proteins. This conserved motif forms a beta-barrel fold found in all of the cupins, giving rise to the name cupin (cupa is the Latin term for small barrel).	0.0027143
NZ_CP007567.1\|WP_041206311.1\|3332771_3333383_-\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	9.99698e-36
NZ_CP007567.1\|WP_041206315.1\|3343566_3344355_-\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|184955	PRK14993, PRK14993, tetrathionate reductase subunit TtrB.	2.15686e-125
NZ_CP007567.1\|WP_041206310.1\|3329390_3329765_+\|cupin-domain-containing-protein	gnl\|CDD\|380395	cd06990, cupin_DUF861, domain of unknown function DUF 861, cupin domain. This family contains proteins which seem to be specific to bacteria and some fungi. The function of this family is unknown but contains a cupin domain without a metal binding site. Cupins are a functionally diverse superfamily originally discovered based on the highly conserved motif found in germin and germin-like proteins. This conserved motif forms a beta-barrel fold found in all of the cupins, giving rise to the name cupin (cupa is the Latin term for small barrel).	1.89775e-57
NZ_CP007567.1\|WP_005326888.1\|3348153_3349545_+\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0

>NZ_CP007567.1|WP_005328600.1|3336918_3337656_+|EAL-domain-containing-protein
MFAFKEEYPMSAMAMMAMADVAVPFYQPIIGRDRQVKGYEALARRWDPVAQCYQGIDFASLSQDESQHLDIVMLRAILRDLPVLAQKGPYTLSINLNPAPSSPTYQNLLLLVLIQARKVGIDIWFEVLEHTRLESQYRALIEVLRAHGAHIACDDFGSLECNFQRLMALPYEVVKLDRSLLLQAACTSHALKMLVGLVKYLQRLGMAVVCEGVETQTHIEIANRLGCDYQQGYAYAMPSPLSRWS
>NZ_CP007567.1|WP_005328601.1|3336455_3336731_+|hypothetical-protein
MFAIWDETGQEQGLSLPQLQQRLHHYQGDVMVRYLNRLGLSTTLFLTIHQGQAYQRFKAGTPPLDWEWLAQAMHGKPLLDAGGHQPEHALR
>NZ_CP007567.1|WP_005328602.1|3334669_3335758_+|ketoacyl-ACP-synthase-III
MKYANITGWGKCLPPAVLTNDALSTIMDTSDEWIYPRTGIKARRVSHVSTQALATLAARRALACAGLDAGELDGIILATATPGTLVPNCASAVQQALGAHKAAVFDLNAACTGFVYALSVATSLVQTGMMQKVLVIGAERLTQLLDWAKRDTAVLFGDGAGAVVIEASEQKSGLIASKLGCDSEAREILHVPNFGTDRVRFADIDGLFTFNFEGQEIFKRAVRGMGEATGVVLTQAGITPEQVDLIVPHQANVRIIETLAKRMNAPMEKVMVNIEQYGNTSAATVPIALCEALEQGRVKPGSHLLTAAFGAGLTWGAALIKWGDRVTPLTHCDDELPPCEQSALELIAHAVQGCQQARPSDA
>NZ_CP007567.1|WP_041206312.1|3333511_3334465_-|LysR-family-transcriptional-regulator
MHKANLNLLPTLKVLLETRNISRAAELLHLSQPSISKQLGQLRSEFGDELLVREGQRWLLTPRAESLAAALADSLGALDRLYAAPEFAPERCERVFRLASSDYVAQHILPDICAALARAAPLAALEYSLWDKRQLPQLWQSELDLVSTITELVPDQIRGLHQGEDRLVMLMGRHHPLSGTAPSLDDYLAWPHLQVSGGGDKDSPVEQVLGPRGLSRRWFARVPFFQAAVEVLLRTDCLMTTPAHIAWQLSREHALSFCDLPFATRVQQYHLLWHQRHHLDPAHRWFRELAYPFLRDHLQRTLGESRKQLGLKADPLR
>NZ_CP007567.1|WP_041206311.1|3332771_3333383_-|LysE-family-translocator
MEMTSWLALAAICAMGAISPGPSLALIIRNTVQGGQGHGVATALGHGLGVGIYALITALGLSLLITQTPLLFDLIRYGGAAFLAWLGVKALLARPASGDAADETVHGARGRQGAFEGFMVAFLNPQLAIFFIALFSQFVHADTGWREGSIMMLTAGGIDALWYVLVVLVLSRGPVLAWLKAKSFVIDKVSGLVLLGLALKVVI
>NZ_CP007567.1|WP_005328605.1|3330711_3332559_-|U32-family-peptidase
MQDHTQTNRLELLAPARNLAYGIEAINHGADAVYMGGPAFGARSAAGNSLEDIEALARHAHRFGAQVFVAFNTLLHDHELEQARRLTHQIHEAGADALIVQDMGLLALDLPPIALHASTQTDNRTPEKVKFLQDVGFSQVVLARELSLEQIRAISAQTQVQLEFFIHGALCVSYSGQCNISHARTGRSANRGECAQLCRLPCSLQTPGGEVLVENSHLLSLKDMDQSANLEALIAAGIRSFKIEGRLKGLDYVKNVTAWYRQKLDAILERRPDLVAASAGRCSYGFTPDPKKSFNRGSTDYFLHGRKPDIDSPRSPKYLGEPLGRVSRVTRDCIEIDGKQVTLNNGDGLGFFKPGGELVGMRLNKVEGKQLLLSERMPGLKVGAEIFRNHDQAFSKLLEKPSADRRIRVDMHLSECDEGLRLALVDEQGISATVTFPCDKLPADNPARALQQARDQLGKLGNTLFEARQIELVFTSPLFIAASVLNGLRRDAIAALEAARLAAYRRPERRIPLRGATYPQHRLSYLGNVLNSAAEQFFRDHGVGRIAPAFEANKELGEVVLMTTKHCIRYSQHLCPKEVPGLKAEPLELKMGKDSFRLRFDCHRCEMQVMGSLKG
>NZ_CP007567.1|WP_005328608.1|3330258_3330588_-|DHCW-motif-cupin-fold-protein
MNINALPFCTTNWADIPPTEHKGERGVARWHTRQFGDLRVRMVEYSPGYLADHWCSKGHVLLCLEGELHTELQDGRVFTLTPGMSYQVADNAEPHRSYTEQGACLFIVD
>NZ_CP007567.1|WP_005328610.1|3329954_3330212_-|DUF1272-domain-containing-protein
MLELRPNCECCDRDLPADTATAYICSFECTFCAECNDQYLHLTCPNCGGELVRRPRRPVAKLVNNPASLKRVFNPVLKATLSKGR
>NZ_CP007567.1|WP_041206310.1|3329390_3329765_+|cupin-domain-containing-protein
MSTPVTVTEFQVKSHGAPDEVRTPDKTRVEVVKLDGYTIGRFNFAPGWRWSDCIKPVVKTEQCQLSHLGYAVSGSLTVRLADGTLKTINAGESYTIPPGHDAWVEGDQPFVGIEVLSADQFAKP
>NZ_CP007567.1|WP_005328612.1|3328566_3329043_+|methylated-DNA--[protein]-cysteine-S-methyltransferase
MIRYDMLPTHCGDLLVAIDERGLVHVDFVAGLRPLPDMSDWRQDGEALAPFLAEFRDYFAGRLRRFTLPLAARGTAFQQAVWQALCDIPYGETRSYGDIARVIGKPSASRAVGAANGRNPLSIIVPCHRVIGQSGSLTGYAGGLPIKQALLHLEGISR
>NZ_CP007567.1|WP_041206313.1|3337945_3339307_+|endonuclease/exonuclease/phosphatase-family-protein
MKNISKSLLAAAISLGLMAGCNSQNDSETPTPMVRFATFNLSFDRTAAGMLTGELSLSRTEQDALLARLADGTLSGAEKTKALDVQQIRNIAEIIQRTRPDVFLLNEFDNDGKGSDTTDLKAFNDNYLAHAQHDEVKAISYPVLQNFATNTGLMSGHDLNLDGKVNSGPDDAWGFGNYHGQYAFAVMSQYPIDTKQIRTFQKFKWKDMPGEVNPVIDDCNNAKAPIPAGRQCGDAWYDDAAWQAFPLSSKNHADVPVRIKRGNKEEVIHFLISHPTPPIFGNAARHNVKHNRAEVAFWQDYVETASYMVDDAGKAGGLPAGAKFVIAGDLNADPQIGDGDLTAIQDLHNHVLVNQAVTNGALIPVSQGGPECLASQPDQCKRNNNRPTPERITSSSGLQLDHVLPSANLNAVASGVFWPASFEPGYHLVYDAKLGIAKGVSSDHRLVWVDFKL
>NZ_CP007567.1|WP_041206314.1|3339363_3342471_-|tetrathionate-reductase-subunit-TtrA
MDHSKRKFLKGAAIAGGTGLFVAGYSDTLKQVASGLATGSSGQPTRDPIHGNSLAVEYRVDEQGELHPNPAQRVANTMCLGCWTLCGVRARIDNERDQIVRILGNPYHPLSARHHIDFKTPVKQALLATSGYQEGGLDGRSTACARGNAMLEQLDSPQRVTRCLKRVGPRGSGRWQSIPFEQLVAEVVEGGDLFGEGQVEGLRAIRNLAEPLDPANPEYGPRANQLLVSNASDEGRDYFIKRFTFNSFGTRNFANHGAYCGLSFRVGAGALLDDLEKNAHLKPDWDESDFLLFMGTSPQQSGNPFKRQSRQLAANRARPGKPFSYVVVAPSLPNTVNMPSAPANRWLPIRPATDSALAMAMLRWIIDNQRYAESFLTAPHAAAAERAGYRGFCNASHLVLCDESHPRFGQMLRASDLGLPFDGEAYGEGDAMLVEEAGSGEPRPAGQCERANLWVDRPLQGPKGELMVKSSFQLLAEACREHSLEQYSAECAVPVADIEALAREFTSHGTRAAVVSHGGTMSANGFYSAWAIMMLNVMIGNLNARGGAVASGGKFDPFGAGPRYDLASFPGMVKPTGVFLSRSKFPYEKTSEYRRKREAGQNPYPAQEPWFPISGPLLGEHLTAAVNGYPYRLKTWINHMGNPLYGQAGLSKAIGEQLKDPAVLPLIVSIDSFINESSALSDYLVPDTLTYESWGWATAWHGVLTKVSTGRWPIVEPRVAKTAEGDPVCMESFFIAVAKRLGLPGFGEGALKGADGKLHALHKAADFSLYGAANVAYLGEPVPPIGPEDLAWSGVERILPVLNTTLSQEEAGRAAYLFARGGRFEPAAKGRDEAGQPSKRWPKPLMVWNPEVGSRRHSQSGQYLSGTPRFFRPQLADGTPLNEAFKPAQWPLLLTSYKSHTMSSMSIGSDRLRQVNPSNRVRLNAQTATQLGIESGDRVRVSTPDGSVIGVAECVAGVQADAIAIEHGFGHKELGAREHWIDGQKVVANPLRGAGVNLNDLAVLDPSRHGRYPLVDWAIGSSARQGLPARVEKLV
>NZ_CP007567.1|WP_005328595.1|3342470_3343577_-|polysulfide-reductase-NrfD
MVINELLAPAQPITWLPWAVQYFFLIGLAYGALWLGVFELWRKAPDPRLQTLAAVLMVAAGLVAPIALTADLHQPARAWHFYAQTRFGSVMWYGAYLLPLFSLLSMLLGWLLLRPALARRGAEGDKIARLARLLCLGSWSGHVWQRPLSLLAALSGLSIALYTGLETMAVAARPLWHTPWLPWLLTLSAVLGAQSALLLLNRLLMGWRAQTESTLLRQSGWTLSLLALSLLGWVLFGGASAAEAAALYRLDPSWRLAAHWLLLTLGLAGLLMLLRRRISARLSLWGLALLGLHLVWGLRWLVLIQGQLAPKYGAGVYLYEIAWGPAGVLGILGTFGLLLALLVALSELVRPSVSPAIKASTTFAREAL
>NZ_CP007567.1|WP_041206315.1|3343566_3344355_-|4Fe-4S-dicluster-domain-containing-protein
MEPSKRRLLSGIAALTAGAALIPVTQVQAQSVPAPRNGRAAISRGDGRKRYGMLIDLRRCVGCQACTVACTIENQPPLGQFRTTVSQYEVSDVAALEAPASQLMLPRLCNHCAEPACLDVCPTGATFQRDDGIVVVNNDWCVGCGYCVQACPYDARFINHETNTADKCTFCAHRLEAGLLPACVESCVGEARIIGDLNDPKSRISRLLREHEPALKVLKPEANTQPRVFYLGMDEAFVSKVDGNPALRTLLTDDGKEIAHGH
>NZ_CP007567.1|WP_005326894.1|3346558_3347170_+|response-regulator-transcription-factor
MPTPARPPLYLVDDDEAVLDSLRFMLESCDERQLFSFSDGERFLAEVDLHQPACLILDCRMPGLSGPEVQQRLKAAQSPIAILFLTGHGEVPLAVESLKLGAVDFLQKPVQLAPLLAAIERAEQATLSAATRFAHLAAFERLTPREHQLLQLIARGHKNQQIAQDLCISVRTVEVCRASLMKRLEAGSLAELMLCYAAVNGQP
>NZ_CP007567.1|WP_005326891.1|3347310_3348051_+|dipeptidase-PepE
MELLLLSNGKTTEHPGLLGWARDRVQTLLARKQVKRILLIPYAVIRSDWDARAQDLAESLGVETISIHQFDDPVDAIQQAEAIFISGGNTWRLNQLLHEYGLVVPIQRAVRERGVPYVGWSAGCNVATPSIRTTNDMPVCSAAVLPALGLFPLQINPHYLDASISGHMGETRDERLAEFCAINPSESVVALREASLLQISGESSGETIEYWSARGEGFKIFKHGETTREYEDARPLAALTPFQPGD
>NZ_CP007567.1|WP_005326888.1|3348153_3349545_+|class-II-fumarate-hydratase
MTVRIEHDSFGDIEVPAARLWGAQTQRSLHHFNISGERQPMEIIHALARIKSACARVNHALGLLPARKAQAIMAAADEVLCGLHDAEFPLMVWQTGSGTQTNMNLNEVLANRASELLGGARGEARLVHPNDEVNKSQSSNDVFPSAMNLAAVTAITSQLLPALTTLKNTLASKAATFDDLVKIGRTHLQDATPLTLGQEISGWVAQLAQGERHLAAALPHLCELALGGTAVGTGLNCPPGFAEAVAQTLAQQTGLPLVSAPNKFEALAASDAQVHAHGALKTLAASLMKIANDVRWLASGPRSGLGELSIPENEPGSSIMPGKVNPTQSEALTMLCAQVMGNDVAINIGGASGNFELNVFRPMIAHNFLQSVRLLADGMRSFHDHCAVGIVANRARIDELLARSLMLVTALNPHIGYDKAAEIAKLAHHQGLTLREAAIASGHLSAEQFDAWVVPADMVGRQP
>NZ_CP007567.1|WP_005326882.1|3350797_3354766_+|trifunctional-transcriptional-regulator/proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MATTTLGVKLDEATRDRLKQAAQTLDRTPHWLIKQAIFTYLEQLERGLTPPEQSGLAAAAGEEAIETLTEQGIQVFLEFAESILPQSVLRAAITSAYRRPETEAVPMLLEQARLPKEKAEATQKLAMSIAEKLRNQKSASGRQGLVQGLLQEFSLSSQEGVALMCLAEALLRIPDKATRDALIRDKISGGNWSQHLGQSASLFVNAASWGLLITGKLVATHNEAGLNSSLKGLIGKGGEPLIRKGVDMAMRLMGEQFVTGETIAEALANAGSMENRGFRYSYDMLGEAALTEEDAKRYLASYEQAIHAIGKASHGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPTLLGLTQLAKQYDIGINIDAEEADRLEISLDLLEKLCFDPSLADWNGIGFVIQAYQKRCPYVIDYVIDLAKRSRHRLMIRLVKGAYWDSEIKRAQQDGLEGYPVYTRKPYTDVSYLACARKLLAVPESIYPQFATHNAHSLSAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVVGKVADGKLGRPCRIYAPVGSHETLLAYLVRRLLENGANTSFVNRIADNSISLQDLVQDPVQQIEQMAAREGSLGLPHPRIPLPRELYGEARPNSAGLDLANEHRLGSLSAALLASTNTAYQALPMLGNEHPGCDTEAPTQFQQVVNPADHRDVVGQVSEATVELVDKALACALASGQIWQSTPPAERAAVLDRAADLMESELQPLMGLLVRESGKTFANAIAEVREAVDFLRYYAAQARNHFANESHRPLGPVVCISPWNFPLAIFSGQVCAALAAGNTVLAKPAEQTPLIAAQAVRILREAGVPAGAVQLLPGRGETVGAALIADERVRGVMFTGSTEVAGIISRNLAGRLDAQGRTIPLIAETGGQNAMIVDSSALTEQVVMDVISSAFDSAGQRCSALRVLCVQDDVAERVIRMLKGAMAEYKVGSPEHLSTDIGPVIDAEAKANIERHIKAMGDKGRRVHQIARTQEGACNRGTFVLPTLIELDSLDELGPEVFGPVLHLVRYPRAKLGELLAQINDSGYGLTLGVHTRIDETIAQVVNTAKVGNLYVNRNIVGAVVGVQPFGGEGLSGTGPKAGGPLYMYRLLGARPQEAVTSQLRQEPGATPQAEAAKPALLALRGWAGKQAPALVALCDRYGELALSGLTQLLVGPTGERNSYSLLPRERVLCLAADDKEAKTDLLAQLAACLAVGTEVLWQDNAQNRTLLTSLPSEVQARIQLVADWASSDIGFDALLHHGDSDQLREVAKLAAARAGAIVGVHGLHRGETDIPLERLLIEHALSVNTAAAGGNASLMTIG
>NZ_CP007567.1|WP_041205051.1|3354883_3356221_+|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNGPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIEKRPRPSRPRAVKISKTRFPVNRNAAPLK
>NZ_CP007567.1|WP_005330481.1|3356453_3357527_-|alanine-racemase
MKAAIAQIDTSALRHNLAVVKRHAPSCKIIAVVKANAYGHGLLPVARTLVDADAYAVARIEEALMLRSCAVVKPIVLLEGFFSSADLPVLAANNLQTAVHTWEQLEALEQAELPAPVVAWFKLDTGMHRLGVRAEEMPAFIERLGKCKNVVQPFNVMTHFSRSDELEQSTTREQIDLFSKLTASLKGERAMANSAGILAWPDSHCDWVRPGVILYGVSPFPNTVAADYDLKPVMTLKTQLIAVRDHKAGEPVGYGANWVSTRDTRLGVIAIGYGDGYPRMAPNGTSVLVNGRIVPLVGRVSMDMTTVDLGPDATDKAGDEAVLWGEGLPVERVADEIGTIPYELITKLTSRVFMEYV

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Crispr_ID: NZ_CP007567_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_10

4159484-4159622

Orphan

Consensus_repeat	Method
GCTTCAACAACTGCGTTCCCACTCCTCATCCCACCAGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_10

>merge|NZ_CP007567|10|4159484-4159622|CRISPRCasFinder
GCTTCAACAACTGCGTTCCCACTCCTCATCCCACCAGCGCGGAAGAGTTTGTGACAATGCGATAAGTACGTTTGAAGTTGGCCTGTCGCTATCAGACCCGCTTCAACAACTGCGTTCCCACGCCTCATCCCACCAGCGC

>NZ_CP007567|10|10|4159484-4159622|CRISPRCasFinder
GCTTCAACAACTGCGTTCCCACTCCTCATCCCACCAGCGC	GGAAGAGTTTGTGACAATGCGATAAGTACGTTTGAAGTTGGCCTGTCGCTATCAGACCC
GCTTCAACAACTGCGTTCCCACGCCTCATCCCACCAGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_041206621.1\|4163575_4165255_+\|potassium-transporting-ATPase-subunit-KdpA	unknown	unknown	gnl\|CDD\|235494
NZ_CP007567.1\|WP_005326342.1\|4151740_4152847_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NZ_CP007567.1\|WP_041207118.1\|4148908_4149712_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|182878
NZ_CP007567.1\|WP_005326326.1\|4167641_4168157_+\|potassium-transporting-ATPase-subunit-C	unknown	unknown	gnl\|CDD\|376890
NZ_CP007567.1\|WP_005326339.1\|4158099_4159449_+\|glutathione-disulfide-reductase	unknown	unknown	gnl\|CDD\|235701
NZ_CP007567.1\|WP_005326329.1\|4165322_4167386_+\|potassium-transporting-ATPase-subunit-KdpB	unknown	unknown	gnl\|CDD\|234905
NZ_CP007567.1\|WP_005326338.1\|4159906_4160695_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NZ_CP007567.1\|WP_041206618.1\|4146936_4147683_+\|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH	unknown	unknown	gnl\|CDD\|236837
NZ_CP007567.1\|WP_041206620.1\|4162802_4163246_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NZ_CP007567.1\|WP_005326341.1\|4152862_4155943_+\|multidrug-efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|169983
NZ_CP007567.1\|WP_005326325.1\|4168351_4170940_+\|sensor-histidine-kinase-KdpD	unknown	unknown	gnl\|CDD\|225115
NZ_CP007567.1\|WP_041206619.1\|4149774_4150278_-\|ricin-type-beta-trefoil-lectin-domain-protein	unknown	unknown	gnl\|CDD\|214672
NZ_CP007567.1\|WP_005326350.1\|4147672_4148713_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|182697
NZ_CP007567.1\|WP_005326322.1\|4172911_4173700_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380379
NZ_CP007567.1\|WP_005326344.1\|4151153_4151744_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NZ_CP007567.1\|WP_005326324.1\|4171003_4171687_+\|response-regulator	unknown	unknown	gnl\|CDD\|223816
NZ_CP007567.1\|WP_005326323.1\|4171691_4172819_-\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NZ_CP007567.1\|WP_005326340.1\|4156064_4158023_+\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|226654
NZ_CP007567.1\|WP_005326354.1\|4144711_4146829_+\|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis-pyrophosphate-3'-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236843
NZ_CP007567.1\|WP_005326337.1\|4160746_4161751_-\|NADP-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|176191

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_041206621.1\|4163575_4165255_+\|potassium-transporting-ATPase-subunit-KdpA	gnl\|CDD\|235494	PRK05482, PRK05482, potassium-transporting ATPase subunit A; Provisional.	0
NZ_CP007567.1\|WP_005326342.1\|4151740_4152847_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	5.47022e-74
NZ_CP007567.1\|WP_041207118.1\|4148908_4149712_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|182878	PRK10976, PRK10976, putative hydrolase; Provisional.	3.19168e-98
NZ_CP007567.1\|WP_005326326.1\|4167641_4168157_+\|potassium-transporting-ATPase-subunit-C	gnl\|CDD\|376890	pfam02669, KdpC, K+-transporting ATPase, c chain. This family consists of K+-transporting ATPase, c chain, KdpC. KdpC forms strong interactions with the KdpA subunit, serving to assemble and stabilize the Kdp complex. It has been suggested that KdpC could be one of the connecting links between the energy providing subunit KdpB and the K+-transporting subunit KdpA. The K+ transport system actively transports K+ ions via ATP hydrolysis.	1.11815e-63
NZ_CP007567.1\|WP_005326339.1\|4158099_4159449_+\|glutathione-disulfide-reductase	gnl\|CDD\|235701	PRK06116, PRK06116, glutathione reductase; Validated.	0
NZ_CP007567.1\|WP_005326329.1\|4165322_4167386_+\|potassium-transporting-ATPase-subunit-KdpB	gnl\|CDD\|234905	PRK01122, PRK01122, potassium-transporting ATPase subunit KdpB.	0
NZ_CP007567.1\|WP_005326338.1\|4159906_4160695_-\|SDR-family-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	3.33565e-86
NZ_CP007567.1\|WP_041206618.1\|4146936_4147683_+\|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH	gnl\|CDD\|236837	PRK11081, PRK11081, tRNA guanosine-2'-O-methyltransferase; Provisional.	1.02878e-154
NZ_CP007567.1\|WP_041206620.1\|4162802_4163246_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	4.71769e-31
NZ_CP007567.1\|WP_005326341.1\|4152862_4155943_+\|multidrug-efflux-RND-transporter-permease-subunit	gnl\|CDD\|169983	PRK09579, PRK09579, multidrug efflux RND transporter permease subunit.	0
NZ_CP007567.1\|WP_005326325.1\|4168351_4170940_+\|sensor-histidine-kinase-KdpD	gnl\|CDD\|225115	COG2205, KdpD, Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms].	0
NZ_CP007567.1\|WP_041206619.1\|4149774_4150278_-\|ricin-type-beta-trefoil-lectin-domain-protein	gnl\|CDD\|214672	smart00458, RICIN, Ricin-type beta-trefoil. Carbohydrate-binding domain formed from presumed gene triplication.	3.04701e-08
NZ_CP007567.1\|WP_005326350.1\|4147672_4148713_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|182697	PRK10749, PRK10749, lysophospholipase L2; Provisional.	5.85526e-106
NZ_CP007567.1\|WP_005326322.1\|4172911_4173700_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|380379	cd06124, cupin_NimR-like_N, AraC/XylS family transcriptional regulators similar to NimR, N-terminal cupin domain. This family contains mostly bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included in this family is Escherichia coli HTH-type transcriptional regulator NimR (also called YeaM) that negatively regulates expression of the nimT operon and its own expression. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	5.09757e-31
NZ_CP007567.1\|WP_005326344.1\|4151153_4151744_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.48123e-14
NZ_CP007567.1\|WP_005326324.1\|4171003_4171687_+\|response-regulator	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.79411e-73
NZ_CP007567.1\|WP_005326323.1\|4171691_4172819_-\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.6261e-77
NZ_CP007567.1\|WP_005326340.1\|4156064_4158023_+\|PAS-domain-S-box-protein	gnl\|CDD\|226654	COG4191, COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms].	7.57664e-34
NZ_CP007567.1\|WP_005326354.1\|4144711_4146829_+\|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis-pyrophosphate-3'-pyrophosphohydrolase	gnl\|CDD\|236843	PRK11092, PRK11092, bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase.	0
NZ_CP007567.1\|WP_005326337.1\|4160746_4161751_-\|NADP-dependent-oxidoreductase	gnl\|CDD\|176191	cd05289, MDR_like_2, alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases. Members identified as zinc-dependent alcohol dehydrogenases and quinone oxidoreductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	1.15918e-134

>NZ_CP007567.1|WP_005326339.1|4158099_4159449_+|glutathione-disulfide-reductase
MAQHFDYIAIGGGSGGIASANRAAMYGKKVALIEAKELGGTCVNVGCVPKKAMWYAGQIADALRYGSDYGFDTTLNHFSWARLVESRQAYIGRIHKSYENVLGKNQITVIKGFARFVSSNTIEVDSEQYSADHILIATGGRPEVPTIPGAEFGIDSDGFFELQAQPKRVAVVGAGYIAVEIAGVMQALGSETHLVVRKHAPLRNFDPMIHETLVEIMAQEGPKLHTHAIPKAVLKNADESLTLQLEDGRHLTVDCLIWAIGRVPATDNLNLAATGITLDEQGFIPTDKFQNTAVANLYAVGDNTGRIQLTPVAVAAGRRLSERLFNNKPNEHLNYDLVPTVVFSHPPIGTIGLTEPEAIAEYGESQVKVYRSQFTAMYSALTQHRQPTRMKLVCVGPEEKVVGLHGIGFAMDEILQGFGVAMKMGATKADFDNCVAIHPTSAEEFVTMR
>NZ_CP007567.1|WP_005326340.1|4156064_4158023_+|PAS-domain-S-box-protein
MSGIFSKAFGLNGLSYRLLSYILICSTVLALVITVLQLAWDYNKDVTVIEASIDQIEASFLQPISASLWNLDEEQVKVQIEGIMNLPNMQFVMVKEMLGNSEVPLLTQGVEQAQYDISREFSLTYQGEVVGKLFVAATLEQVYQRLIEKSVLILVSQTIKTLVVSLCILVIIYYLVIRHINRIVSYAQKLSLDRLAVELTLEGRPLPRKHPDEFDALAATLNQMRTRLNDEFTARHQAADQLQQERDFSATLINSANMVICCMEPDLNIASINPAAILLTGYHHEELLQHNWLDLFVSQEQRAELAAILSDQGSLDDREIIMHDQQGHELVLQWTFAPFYEGPNLKYLIGFGYDITRLKKVEREITLFNEQLEGKVVERTRSLSDANDQLGKAYDDLKQAQQTLVESEKMASLGSLVAGVAHEINTPIGISVTASSYLQEQVADFKQHLEAKQLSRSYLNEFTQNLDESMQLLQGNLRRASELIASFKQVAVDQSSEARYNFSLADNLHQVVVSLGYKLKKAQCEVDIQCDPKLAIYSFPGSFTQIYSNLILNSIHHGFDGWDRPKKITIRVEQQGDELVIDYSDNGRGIPPEILPRIFDPFVTSKRGQGGSGLGTHIIYNLVVQLLRGRIHCASEPGQGAQFHIRLPIQQN
>NZ_CP007567.1|WP_005326341.1|4152862_4155943_+|multidrug-efflux-RND-transporter-permease-subunit
MRFTDIFIKRPVLAISLSFLIALLGFQAIFKMQVREYPEVINTVITVNTSYYGASSDLIQGFITQPLEQAVAQADNIDFMTSSSQLGSSTVTAYMKLNTDPNAALSDILAKVNSVRSQLPKEAEDPSVTSSTGSTTAVLYMGFTSPELNSSQITDYLERVIKPQLFTVGGVSKVDLYGGVEFALRVWLDPAKMAAFDLTASDVMTVLNSNNYQSATGQATGYFTLFNGNAETQVSNTDELKRLVVATRDGKVIRLSDIAKVSLEKSHDIYRASANGREAVVLAINAAPTANPINIAHDVLELLPSLKSNMPSTMQVNILYDSTIAINESIHEVIKTILEAAAIVLVVITLFLGSFRAVIIPIITIPLSLIGVVMMMDMFGFSINLMTLLAMVLAIGLVVDDAIVVLENVDRHIKEGEEPFRAAIIGTREIAVPVIAMTVTLAAVYAPIALMGGITGSLFKEFALTLAGAVFVSGIIALTLSPMMCAKMLRANETPSKFESTVHHLLDRMTARYDSMLHAVMQKRIVVILFAVIVFGSLPLLFKFIPSELAPSEDKGVMAVLGTAPSNANLDYIENTMADVNKVLDDQPEIAYSQVFSGVFNANQAFGIASMVPWSQREASQKEVLDRVAGLVKDIPGMAITTFQFPELPGASSGLPIQFVITTPNSFESLFLIAGEMLAATQANGQFVYSDLDLNYDSATMKISIDKDKAGAYGITMQDIGTTMGTMMADGYVNRIDLDGRSYEVIPQVERKYRLNPESIKGYYVRAADGKSIPLGSLIKIEVVGEPRALPHFNQLNSATIGAVPAPGVAMGDAINWFKATAEEKLPQGYRYDFMGEARQFVTEGNALYATFALALAIIFLVLAIQFESVRDPLVIMVSVPLAISGALIALAWGMATMNIYSQVGLITLVGLITKHGILICEVAKEEQLLHGMNRMQAVMQAAKVRLRPILMTTAAMIAGLIPLLYAAGAGAAQRFSIGIVIVAGLAIGTLFTLFVLPVIYTFLASEHKPLPEFDESIPAKAKGSH
>NZ_CP007567.1|WP_005326342.1|4151740_4152847_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MKKWMAIMLLIALALFGSVIGFNMFKQKKIAEFMANRPEPEFPVTAMVTKAQDWVPTIEAIGFIEPNQGVTLSSELAGTIDKISFESGAQVKADQLLLSLDSSVEKANLNSSQARLPAARAKFQRYQNLYQKNSISRDQLDDAEASYRSLEADIESLKGTINRREVRAPFGGVVGLRNVFLGQYLEPGTEIVRLEDTSVMRLRFTVPQTDISKISLGQTIKINVDAYPQTQFDGQITAIEPAVNYQSGLIQVQANIPNNGGQLRSGMFARASIILPTVKDQIVIPQSAISFTLYGENVYVIHEADGVKRAKQVVVKAGERRGNDVHVLSGIKAGDQIVLSGQVRLSNDTKVHVVDNDALAVPAQTPML
>NZ_CP007567.1|WP_005326344.1|4151153_4151744_+|TetR/AcrR-family-transcriptional-regulator
MDKKERIFEAAHEILGEQGFYGLSIAMVAKKAKVAAGTIYRYFSDKDDLVRQLYLHTILKCHPQIMEGVQIEEVSYRQYRRLWLNIDAIFTNYPNALKCKLQYESSPLGAELERDPVIMATWAPLERFFEQGRQQGLFIDLPVLVLQALSLDCVANLAQQRRVHDFVLTQEQLETVIRASWNAILNLNHSITGACS
>NZ_CP007567.1|WP_041206619.1|4149774_4150278_-|ricin-type-beta-trefoil-lectin-domain-protein
MPFHIRLLALMALLLGGCALPPRPENLLLEAASSSTSIPPATLVTDGGFCVALNEQGRLLTQPCDQEPNQLFIWDAGALLLAQGCLIATGTDGLVVGGCENDSHQWQWQGDRLFNRQVSLCLDVAGRRHRSAVPLRLAECYGGANQSFTWTPTGSLLERLMPPSSIW
>NZ_CP007567.1|WP_041207118.1|4148908_4149712_+|Cof-type-HAD-IIB-family-hydrolase
MFKVVVSDLDGTLLNGQHQISPRTRDTLHRLVDQGIKFVVATGRHHVDVRSIRDALGLDIYLITSNGAVVHDKQDSLVFNQALPSTVAAELIALERDPSIHINVYYGDEWLVEEEMPWLLQFHHDSGFSYRLTDLASHPLDKINKVFYIGEHEKLLQIEAELNQRYGDRINVTFSLPDCLEVMHAGVHKGNAVRAVLEQHGLEMSQAVAFGDGMNDFEMLSMVGRGVVMGNAHDRLKLALPNHDQTLSSDEDGVAVYLERLFAPVVA
>NZ_CP007567.1|WP_005326350.1|4147672_4148713_+|alpha/beta-fold-hydrolase
MKFNALPLLALTLFSAGALAVTNPYQLTTEADVPALHQQTLPDFWRDHAAPGEFKGKDGVTIRYAALRQAKVDRAILLVNGRVESYLKYQELAWDLWRQGYSLYLIDHRGQGLSDRLLADKEKGYVADFDDYVLDLKQFHDEVILADKPAKLFLLAHSMGGAISARYLEHWPDDVEAAVLSSPMMGINLGGLPKWLAQGLAATMDTVGSWWGEPPYGPGQTGYVSHEFADNGLSHSKPRYQAFRQLYEQHPQIKLGGVTAHWIREGIKAGDAAIAEADRIKTPLLLIQAGEDGIVDNQAQDSFCDRLQCEGGKPLRIEGAWHELFIEADAQRLPALTATLDFFARF
>NZ_CP007567.1|WP_041206618.1|4146936_4147683_+|tRNA-(guanosine(18)-2'-O)-methyltransferase-TrmH
MTPERFKRISDMLAQRQLDLTVCMEEVHKPHNLAAIVRTADAIGIHRVHAVWPKTWIHKRKGTARGSQNWVDVKLHPDIGSAVAELKASGMQILATHLSESSVDFRAIDYTKPTAILVGQEKHGIGEEALALADHHIVIPMVGMVQSLNVSVAAAAILYEAQRQRQLAGCYQRGCPLDLEEQNSILFEGGYPIYAQLCKEKEMPYPQLGPAGEILADEAWWQRMQLTRKGWAAQQDDPLDMEYPTDEV
>NZ_CP007567.1|WP_005326354.1|4144711_4146829_+|bifunctional-GTP-diphosphokinase/guanosine-3',5'-bis-pyrophosphate-3'-pyrophosphohydrolase
MYLFENLKEIASSYLPSEQVEKLRQAYVVARDAHQGQMRSSGEPYITHPVAVARILGDMRLDHETLMAAVLHDVIEDTPVTKDDLAELFGNAVAELVSGVSKLDKLKFRDRKEAQAENFRKMVMAMTQDIRVILIKLADRTHNMRTLGSLRPDKRRRIARETLEIFAPIANRLGIHTMKNELEELGFEALYPMRSRVLRESVRRARGNRREIIDSIQSEIEGRLREAGIDAQVSGREKNLFSIYNKMEKKELQFHEVMDIYAFRVRVKDIDTCYRVLGQMHSLYKPRPGRFKDYIAIPKSNGYQSLHTSLVGPHGVPVEVQIRTEFMDQMADKGVAAHWAYKQDGDSSGTTAQIRAQRWMQSLLELQQSAGSSFEFIEGVKTDLFPDEIYVFTPEGRIMELPAGATPVDFAYTVHTDIGHACVGSRVDRHPYPLSSPLHSGQTVEIITAPGARPNAAWLNFVVTTKARSKIRQFLKNLRTEESVVLGRRLLNHALGAKNIEDIPEPRIKQVLADTKHENLQGLLADVGLGNAMSVMVARRMLGDELPPEEQPKSSSKKMPIKGADGMLVTFANCCRPIPGDAIIAHISPGKGLVIHQESCRNIKGYSREPDKYLPVQWEVDKEQEQEFRTGISIEIVNHQGALAELANVIAATGANIHAISTEEKDGRVYLVTLLITTKSRIHLANIMRKIRVMPNVLRVSRQKN
>NZ_CP007567.1|WP_005326338.1|4159906_4160695_-|SDR-family-oxidoreductase
MTTLPTVFITGASSGIGATYAERFARCGHDLVLVARNKSRLDALAMRLREQHQIAVEVLQADLTNSAELPALETRLRHDARIGILINNAGMLQSGHFLEQSPEAIESQIALNITALTRLAAAIAPRLAQSGTGSIVNIGSVVGFSPEFGISLYGATKAYVLFLSQGLAHELSPQGVYVQAVLPAATRTEIWAHAGVDVNTLPEVMEVGELVDAALVGFDRRELVTIPPLHVAERWTALDEARQGLMSDLRQAHAAERYQPQV
>NZ_CP007567.1|WP_005326337.1|4160746_4161751_-|NADP-dependent-oxidoreductase
MKALTFKRYGKSPEIGITDIPRPALKADEMLVQVYAAGLNPIDNMIPTGMFKPVLHFQLPATLGSDLAGVVTEIGSQVTRFKPGDAVFASIFDLGTGSLAEFAVVPERAAALKPANLDFVQAASIPMVGLTSWQALKERANLQAGQKVFIPAGSGGIGTFAIQLAKLLGAKVGTTVSSGNIELVRELGADEVVDYKQQAFEHQLHGYNAVLGTVRGDAIEKAIDILKPGSKIISLTGPLDAAFARARGLNVLLRLLFGLMSRKIRSRAKKRNVTYSFLFVRPDGDQLTEIGELLDAQRIKPVIDKVFPFDQAKEALEYLAKGHARGKVVVSIKQ
>NZ_CP007567.1|WP_041206620.1|4162802_4163246_+|helix-turn-helix-transcriptional-regulator
MNIKKSYDTPCPIARSMAIAGDAWSILILRDAHAGLTRFDQFRKSLGIAPTMLTRRLATLTEEGLLEKRLYSEHPPREEYLLTAAGRDFLPILFMIGEWGRQYRGDDNMIRFFDMEAGTEIKAIVVDEVTGAKIGTRPLRVVMPDES
>NZ_CP007567.1|WP_041206621.1|4163575_4165255_+|potassium-transporting-ATPase-subunit-KdpA
MWQEIIYPVAFVLLVLLPAPLLGSYMYRVFEGKSRWLAPVERATLACCGTDGREQDWKSYALSLLAFNGAGFGLLFLILMAQGLLPLNPQQLPGLSWQLAFNTAVSFMTNTNWQAYSGEASLSYFSQMVGLTTQNFVSAATGATVAVALFRGLSRQQTIHLGNFWQDLVRFCLYVLLPMALIMALLLVWQGVPQSLSAYLPFHALEGQEQLLPLGPAASQIAIKQLGSNGGGFFGVNSAHPFENPTALSNWLEMVTLLTIPAALVCTLGRYVKDSGHGRAILSAMTLLFVLGLGLSVYQELQPDPALAQLTTQAGNWEGKESRFGPVLSSIWEVATTSASNGSVNAMHDSFTPLGGMVGMINMLLGEVIFGGVGAGIYGMMLFVLLTVFLCGLMVGRTPTYLGKRLGITEMKWVVASMLVMPVGVLVIGGVTLLMPDAATIMGHDGPHGLSRLIYAYASAAGNNGSAFGGFAAADNWQCVAIGLAMLLGRFGYIIPVLAIAGQLSRASQQDAGEGDFPIRGPLFITLLIITVLLIGGLSFLPVLALGPVAEHLLILGAL
>NZ_CP007567.1|WP_005326329.1|4165322_4167386_+|potassium-transporting-ATPase-subunit-KdpB
MSKSISIPARTEKVKGKGKKQTSQVVQAMIEAFYRFNPKALFGSPILFTLWLAAVMATVESLLGQPLSGVTPSLAWQLTAWLWLTLWFANFAETLAEGRGKARADSLKAGMSQLQARKVRDPKDGQGEWIPATSLQKGDLVLVRSGEMIPADGEVIAGIASVNEAAITGESAPVIRESGTDRSGVTGNTTVVSDEIWVRVTNNPGESTLDRMIALVEGAKRQKTPNEMALDALLVGLTLIFLLVVATLPWFLDYNGTQVPRLYLLALFITLIPTTIGGLLSAIGIAGMDRLVKLNVIAKSGRAVEAAGDVRTLLLDKTGTITFGNRMADELIPAPGVDPSLLAQAAMLASLGDNTPEGKSILTLAGKSMAKPSQLESDKVIPFSAETRLSGLDRNGHQYRKGAVDAVLNYLSLDRKGVPELILKAVDNIARQGGTPLLVCTHEQLLGVVYLKDIIKPGIKARFQILRHMGIRTVMITGDNPLTAAAIAAEAGVDDFIAEATPEKKLAYIRQEQADGRMVAMCGDGASDAPALAQADVGLAMNEGTQAAKEAGNLVDLDSNPTKLLDVVLVGKQLLVTRGALTTFSIANDVAKYFAILPALFIAAYPQLGALNLMQLGSPESAILSAIIFNALIIVALVPLALRGVNVKGSAASLLRRNLLIYGLGGLIVPFIGIKLIDLVITGLGLV
>NZ_CP007567.1|WP_005326326.1|4167641_4168157_+|potassium-transporting-ATPase-subunit-C
MIAIRTLLTLTLLLGVGYPLAVTGLAQLFFPWQANGSQLTDAKQQLVGSALLAQKFERAEYFHSRPSASDFTTIGSGASNLGVSSPLRSEFAKAQGNYQSPAMLTRSGSGLDPHLPLDAVLAQVDRVAKQRGLDPASLTEQVKSSTQAGILGPQVVNILQLNLLLDQHKDA
>NZ_CP007567.1|WP_005326325.1|4168351_4170940_+|sensor-histidine-kinase-KdpD
MRDEVRADALLASLEEEHKGKLKVFLGAAPGVGKTYAMLQAVREQAKEGVDILIGVVETHGRQETLALLDKLAIQPRKLHHHRQQRLEEMDLDGLLERKPAIVVVDELAHTNAPGSRHEKRWQDVEELLGAGIDVYSTLNVQHLESLNDLVWQLTGVRVKETLPDQVLLEADSIVLIDLPPKELLGRLKEGKVYVPHQAKAALQSFFSLNNLTALRELAMQTAASHVEGDLQLQWQAAGKTTLPLRGKLMVCLGDQHGAALVRYGHRFAQRRQLPWLVVHIDSKGQRSPELEQALALASQLGARVLTLSSPAVADALLETAEQQQVSQLLLGKPHSPPWRRSLVQHLLKQAQGFEITLVDTGKRKPSLKLHPAGPREIRQSLLALLIMGTTSAIAWGFSHWLPSASLPLLFVLGVLATALSTSLVPAILAAVLGFVGHNLLFTAPYFSLSVANHSDLLNLFVLLIVGMTAGRLASRQRQQLVGLRETQQLGNALLSLSQGLATASSPVEVLRQGTQAISLALGQPVFALDEEYQYRAGDEVRGPGQTDKAAIDWCLAQKQSAGAHTATLNAAEAQYHHLTDDLVLGIRLASPLASSAEHQLQALLTDIRAALARIDLNERLADSQLQAETDRMRAALLSSVSHDLKTPLATIMGAGSTLLEYGDRISAEDRNELLHSVQEEARRLHSYVQNLLDMTRIGSPDFQLKREWVDLADLVESARKRLDSSWRQHRLLIHFDQQIPQLYVHGALIEQVLVNILDNASRYSPAGTPIEFKVMLADPDLIIDIIDIGVGIAESDRDKIFNLFYTQPVGDCGSRGTGLGLAISRAMIEAHGGRIWAFAGPNGNGTCMRISLPLSLNAPEV
>NZ_CP007567.1|WP_005326324.1|4171003_4171687_+|response-regulator
MAHILVIDDEAAIRRFLRISLVAEGHQVSEAVGVNEGLAQYRHLNPDLVILDLGLPDGDGIQILHAIREHQPNPVLVLSARDSEQEKVRLLDAGANDYMSKPFGIGEMMARIRALLRQRAGVSSGECRHFPQCGLSLDTGSHKVTMKDEEISLSRKEFALLQALVCHPGKLVMQTQLLNDIWRPSHKEDTHYLRIVIASLRKKLGDNPQQPSLIETEPGIGYRFIDS
>NZ_CP007567.1|WP_005326323.1|4171691_4172819_-|multidrug-effflux-MFS-transporter
MNNKLPPLWLVVGLMMFPQIVETIYSPALTQIATQFRVSDGQASQTLSVYFLAFAVGVVCWGRLCDLIGRRPAMLAGLLTYGLGTLLALLVTEFETLLLARIISAFGAAVGSVVTQTMLRDSYQGSDLAKVFSVMGAALSISPVLGLVSGGLLAEQFGYLGVFSDLMVLALVLGLIASWRLPETRPETTTSIALWPLACRMARDGGLWRSALLVALFNTMLFGYYSLAPFLFAEQGWSASEFGYSGTVLALATLLGSLLNKRLLGKGWQPASLIQLAASLALGAGAAVWASQSSLWFLLPMMGVVVAYGIAIPNVLSQALLAYREVAGSAGALFGLAYYLLLSLGLALAAGLQDLGLLIVGCGLVAVLCSGRRST
>NZ_CP007567.1|WP_005326322.1|4172911_4173700_+|helix-turn-helix-transcriptional-regulator
MAFILPDHPFDPDRLNGGVIGIASALGWHDSGQHVHQCHQLLFAQAGCMTIELGNQVYLLPPSRAAWLPAGVPHQVLMRGVVAYRSLYFTPQPELPASVQVVAVNPLLREIIERMALWPWNKPEAEQRLTLALFMEELAQAPQETWQLPLPTDARLGAWLQEIKRGNTLPERLNRLAERVGASDKTIGRIFMKETGMNYQAWRQQWRLLRAMELLAEAVPISRIATALEFSSDSAFISFFKQHTGQTPLRYLNSRGESHQPS

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Crispr_ID: NZ_CP007567_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_11

4647833-4647929

Orphan

Consensus_repeat	Method
TGAACACCTTGCCGATCTCCTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_11

>merge|NZ_CP007567|11|4647833-4647929|CRISPRCasFinder
TGAACACCTTGCCGATCTCCTCCGACCATAGCCGGTGAGCCGGCCCTACATCTAGCCCTTGGGCTGCTCGTAAGTGAACACCTTGCCGATGTCCTCC

>NZ_CP007567|11|11|4647833-4647929|CRISPRCasFinder
TGAACACCTTGCCGATCTCCTCC	GACCATAGCCGGTGAGCCGGCCCTACATCTAGCCCTTGGGCTGCTCGTAAG
TGAACACCTTGCCGATGTCCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_041205253.1\|4656532_4657870_-\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP007567.1\|WP_041206760.1\|4634557_4635133_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369095
NZ_CP007567.1\|WP_025325515.1\|4646652_4647123_-\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NZ_CP007567.1\|WP_005330947.1\|4657990_4658701_-\|HAD-IA-family-hydrolase	unknown	unknown	gnl\|CDD\|182696
NZ_CP007567.1\|WP_005327726.1\|4654110_4654920_+\|sugar-phosphatase	unknown	unknown	gnl\|CDD\|182509
NZ_CP007567.1\|WP_180345053.1\|4658747_4659671_-\|tyrosine-recombinase-XerC	unknown	unknown	gnl\|CDD\|234698
NZ_CP007567.1\|WP_005327753.1\|4643483_4644053_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380339
NZ_CP007567.1\|WP_005332418.1\|4632548_4633442_-\|sulfate-ABC-transporter-permease-subunit-CysW	unknown	unknown	gnl\|CDD\|226665
NZ_CP007567.1\|WP_005332399.1\|4630342_4631290_-\|HTH-type-transcriptional-regulator-Cbl	unknown	unknown	gnl\|CDD\|237172
NZ_CP007567.1\|WP_005330951.1\|4659696_4660377_-\|DUF484-family-protein	unknown	unknown	gnl\|CDD\|225701
NZ_CP007567.1\|WP_005327752.1\|4644168_4645320_+\|benzoate/H(+)-symporter-BenE-family-transporter	unknown	unknown	gnl\|CDD\|281578
NZ_CP007567.1\|WP_005327724.1\|4656052_4656457_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_005327730.1\|4652367_4653996_+\|DUF342-domain-containing-protein	unknown	unknown	gnl\|CDD\|377177
NZ_CP007567.1\|WP_005327739.1\|4650240_4651404_+\|competence-protein-CinA	unknown	unknown	gnl\|CDD\|179629
NZ_CP007567.1\|WP_005332405.1\|4631406_4632474_-\|sulfate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213263
NZ_CP007567.1\|WP_005327731.1\|4651411_4651927_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|183256
NZ_CP007567.1\|WP_041204874.1\|4645467_4646532_+\|DUF3103-family-protein	unknown	unknown	gnl\|CDD\|371456
NZ_CP007567.1\|WP_005327754.1\|4642283_4643480_+\|NnrS-family-protein	unknown	unknown	gnl\|CDD\|377571
NZ_CP007567.1\|WP_005332419.1\|4633438_4634278_-\|sulfate-ABC-transporter-permease-subunit-CysT	unknown	unknown	gnl\|CDD\|131194
NZ_CP007567.1\|WP_041206762.1\|4655285_4656056_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|336781

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_041205253.1\|4656532_4657870_-\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	5.62528e-32
NZ_CP007567.1\|WP_041206760.1\|4634557_4635133_-\|alpha/beta-hydrolase	gnl\|CDD\|369095	pfam06821, Ser_hydrolase, Serine hydrolase. Members of this family have serine hydrolase activity. They contain a conserved serine hydrolase motif, GXSXG/A, where the serine is a putative nucleophile. This family has an alpha-beta hydrolase fold. Eukaryotic members of this family have a conserved LXCXE motif, which binds to retinoblastomas. This motif is absent from prokaryotic members of this family.	1.08473e-54
NZ_CP007567.1\|WP_025325515.1\|4646652_4647123_-\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	4.77279e-36
NZ_CP007567.1\|WP_005330951.1\|4659696_4660377_-\|DUF484-family-protein	gnl\|CDD\|225701	COG3159, COG3159, Uncharacterized protein conserved in bacteria [Function unknown].	1.63417e-37
NZ_CP007567.1\|WP_005327726.1\|4654110_4654920_+\|sugar-phosphatase	gnl\|CDD\|182509	PRK10513, PRK10513, sugar phosphate phosphatase; Provisional.	2.49033e-104
NZ_CP007567.1\|WP_180345053.1\|4658747_4659671_-\|tyrosine-recombinase-XerC	gnl\|CDD\|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	2.52661e-157
NZ_CP007567.1\|WP_005327753.1\|4643483_4644053_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	2.47425e-19
NZ_CP007567.1\|WP_005332418.1\|4632548_4633442_-\|sulfate-ABC-transporter-permease-subunit-CysW	gnl\|CDD\|226665	COG4208, CysW, ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism].	7.41276e-138
NZ_CP007567.1\|WP_005332399.1\|4630342_4631290_-\|HTH-type-transcriptional-regulator-Cbl	gnl\|CDD\|237172	PRK12683, PRK12683, transcriptional regulator CysB-like protein; Reviewed.	0
NZ_CP007567.1\|WP_005327752.1\|4644168_4645320_+\|benzoate/H(+)-symporter-BenE-family-transporter	gnl\|CDD\|281578	pfam03594, BenE, Benzoate membrane transport protein.	1.29045e-140
NZ_CP007567.1\|WP_005330947.1\|4657990_4658701_-\|HAD-IA-family-hydrolase	gnl\|CDD\|182696	PRK10748, PRK10748, 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YigB.	1.08081e-56
NZ_CP007567.1\|WP_005327730.1\|4652367_4653996_+\|DUF342-domain-containing-protein	gnl\|CDD\|377177	pfam03961, FapA, Flagellar Assembly Protein A. Members of this family include FapA (flagellar assembly protein A), found in Vibrio vulnificus. The synthesis of flagella allows bacteria to respond to chemotaxis by facilitating motility. Studies examining the role of FapA show that the loss or delocalization of FapA results in a complete failure of the flagellar biosynthesis and motility in response to glucose mediated chemotaxis. The polar localization of FapA is required for flagellar synthesis, and dephosphorylated EIIAGlc (Glucose-permease IIA component) inhibited the polar localization of FapA through direct interaction.	1.87506e-144
NZ_CP007567.1\|WP_005327739.1\|4650240_4651404_+\|competence-protein-CinA	gnl\|CDD\|179629	PRK03673, PRK03673, nicotinamide mononucleotide deamidase-related protein YfaY.	1.75627e-88
NZ_CP007567.1\|WP_005332405.1\|4631406_4632474_-\|sulfate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213263	cd03296, ABC_CysA_sulfate_importer, ATP-binding cassette domain of the sulfate transporter. Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.77186e-158
NZ_CP007567.1\|WP_005327731.1\|4651411_4651927_-\|metal-dependent-hydrolase	gnl\|CDD\|183256	PRK11648, PRK11648, metal-dependent hydrolase.	6.69136e-66
NZ_CP007567.1\|WP_041204874.1\|4645467_4646532_+\|DUF3103-family-protein	gnl\|CDD\|371456	pfam11301, DUF3103, Protein of unknown function (DUF3103). This family of proteins with unknown function appear to be restricted to Proteobacteria.	3.63428e-167
NZ_CP007567.1\|WP_005327754.1\|4642283_4643480_+\|NnrS-family-protein	gnl\|CDD\|377571	pfam05940, NnrS, NnrS protein. This family consists of several bacterial NnrS like proteins. NnrS is a putative heme-Cu protein (NnrS) and a member of the short-chain dehydrogenase family. Expression of nnrS is dependent on the transcriptional regulator NnrR, which also regulates expression of genes required for the reduction of nitrite to nitrous oxide, including nirK and nor. NnrS is a haem- and copper-containing membrane protein. Genes encoding putative orthologues of NnrS are sometimes but not always found in bacteria encoding nitrite and/or nitric oxide reductase.	1.45802e-93
NZ_CP007567.1\|WP_005332419.1\|4633438_4634278_-\|sulfate-ABC-transporter-permease-subunit-CysT	gnl\|CDD\|131194	TIGR02139, permease_CysT, sulfate ABC transporter, permease protein CysT. This model represents CysT, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysW (TIGR02140). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions].	7.32365e-132
NZ_CP007567.1\|WP_041206762.1\|4655285_4656056_+\|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein	gnl\|CDD\|336781	pfam07722, Peptidase_C26, Peptidase C26. These peptidases have gamma-glutamyl hydrolase activity; that is they catalyze the cleavage of the gamma-glutamyl bond in poly-gamma-glutamyl substrates. They are structurally related to pfam00117, but contain extensions in four loops and at the C-terminus.	3.03279e-87

>NZ_CP007567.1|WP_025325515.1|4646652_4647123_-|Lrp/AsnC-family-transcriptional-regulator
MRNLDQLDLDILAHLFRDAGMTNKDLAALVGVAPSTCLERVRKLQQDGVLKGAHCEVDYQALGGHIQAMVSLQLARHSRQIIDAFRDAILALPEVISLFHMGGKDDFLVHLCVADTEHLRNFVFDHFTSREEVVHLETSLVFEHRFSRSLPCFTHP
>NZ_CP007567.1|WP_041204874.1|4645467_4646532_+|DUF3103-family-protein
MRNQAVILLLTLLGTASAYAADTDRELARQLALQQKNLLPLLANQEYQSPLPNLLQKASPRLKRQANDANQAAISRQGLDGEIKQLMQLRLANPEQAAALQQGVDPLVAYVPSGDEKSWSAIEAFDSAGNPVYLDVNQPPARPVLVVEADPVKAKNAGLKVMRKALAAADMQVAPRVTGNTAPLKTSILKKIRLSDDQEPWLLGAAEVYAVVAGVNPGRDEPVVDIVDMPYLDHDNTDYTPNQILVYWDRYRWGAVDLVMMEQDDNVNYKELSALLIEALKLGFTAGGVPEALPFLDLGGRIVKALPDSWMTNNDDYLDTFYTLEQDQSYHQYPGAAGNAVITLEPKEIQPTRP
>NZ_CP007567.1|WP_005327752.1|4644168_4645320_+|benzoate/H(+)-symporter-BenE-family-transporter
MPFAFPHLVAGLIAVLVGYTSSVVLIIQAATAAGADAAQVSSWLWTLGIGMGVSCIGLSLYYRIPVLTAWSTPGAALLITSLGNFSLSEAIGAFIASSLLITLCGISGWFDRLMRHIPAPLAAAMLAGVLLRFGLDLFKVAPQDPLLLGASLLAFLLGRHLWPRYTMVLILSAGMLLCTLRGELQLAEVHWQLSSPVWITPTFSINALLGIALPLFIVTMTSQNMPGITILRAHGYQPATSSLIGWTGLTGLLLAPFGGYAFNLAAITAAICMGKEVDPDTARRWPAAVWAGCFYLLTGCFGATVVALFSAFPTALVTCVAGLALLGTIGSSLHAALQQDEEREAALLTFLITASGISLLGVGSACWGLLVGVALHQVNRLRA
>NZ_CP007567.1|WP_005327753.1|4643483_4644053_-|helix-turn-helix-transcriptional-regulator
MQEMNRHLAQRLKGLRSELGWSLDVAARETGVSKAMLGQIERGESSPTVATLWKIATGFRVSFSSFIEPTPAVAGETLYRTADDIRQQPAGEGMQVAPLFPYEGRFGFELFELTLLPGYQRESEPHETGVTEHVIVISGVMEVLVDGQWRSLEQGEAVRFVADRPHGYRNLGIAPAVFHNLIHYPATRA
>NZ_CP007567.1|WP_005327754.1|4642283_4643480_+|NnrS-family-protein
MHQILDSHKEEQIVPLFRLGFRPFFLLGALFSCLAMLGWLGQLNGWFALPGIGNPIWWHAHEMLFGFGAAIVAGFLLTAVQNWTAHPGVRSWPLALVVGLWALPRCLLPWLGEDNIILMALDLAWLPLCAWFLAKPIIMTRQWRNLFFVPLLLILTLLNGATWLWRDDWNTVEHLLITTVLLFTTLIAVMGGRVIPFFTARGTGQEKAPPRPWLERGALASLWLILLLWLLLPGSWANSLYTMPLYIVAAGLHLCRQLRWQPGDTLAHPLLWSLHLAYLFIPLGLLALTAQAAGLPLSLSLASHLLSAGCMGTMILGMIARVSLGHSGRALHVGRRITMAFALVIVSALVRVLIPLYWPTLTLTGWNLSGWSWIAAYGLFVWVYTPILTRPRVDGRPG
>NZ_CP007567.1|WP_041206760.1|4634557_4635133_-|alpha/beta-hydrolase
MNKILLVPGLHNSGPDHWQSRWHQQFPQWQRMLGLPWDKPDLTVWSAKLASKLRSRRSRVHLVAHSFGALTAIAAARLQPDKVSSILIVAPADPARFGIPDEALAGSIKVSAQLIASRNDPWMSFERAEYWSRQWQGPLFDAGEVGHINAQSGHGEWSQGLNLLNTLHHRAEMVVDPASTEWGRRAALSFR
>NZ_CP007567.1|WP_005332419.1|4633438_4634278_-|sulfate-ABC-transporter-permease-subunit-CysT
MRLSSYSVLPGLGPTLGFSLLYLSILVLLPLSALVLFAVNNLTATEFWQVIGSPRVLASFRLSFGAAFVAALLNSLFGLILAWVLVRYSFPGRRLVDALIDLPFAMPTAVSGIALCAIFAPNGWIGQWVAPFGIELAYNPIGVVIALTFIGLPFVVRTLQPVLREAETEQEEAAASLGANRWQTFARVLWPTLIPALLTGFALAFARGVGEYGSVIFIAGNLPMVSEIAPLMIMSHLEEYDYAGASAIASVMLLISFVLLLIINKLQAWSWARIGGSRI
>NZ_CP007567.1|WP_005332418.1|4632548_4633442_-|sulfate-ABC-transporter-permease-subunit-CysW
MNASNASLDLVLDGAPATQVRQPAVTREPAWVKWLLISVGLGWFAALLLLPLATVFIQALSPGLAFFWHAISEPDALSALGLTALVTLCSVPLNLLFGLAAAWAIARFRFPGRQLLITLIDLPFSVSPVIAGLMFVLMFGSRGWFGDWLSEHDIKIIFATPGIILATTFITVPFVVRELLPQMEARGPEEEEAAIMLGASGLQMFWRVTLPGIRWSLMYGLLLCTARAVGEFGAVSVVSGHIRGQTNTLPLHIEILYNEYQTGAAFAVASLLALFGIFTLLGETLLARLRAQPTQSH
>NZ_CP007567.1|WP_005332405.1|4631406_4632474_-|sulfate-ABC-transporter-ATP-binding-protein
MSIQVQRLNKHFNQYAALADINLDFHDGELVALLGPSGCGKTTLLRIIAGLEQADSGNVIIRGEDASDLHVRERNVGFVFQHYALFRHMTVFENVAFGLRVKPRSDRPNEASIRARVKELLDLVQLSHVAERYPTQLSGGQRQRVALARALAVQPKVLLLDEPFGALDAQVRKELRRWLRELHDELHVTSLFVTHDQEEALEVADRVVLMNAGRVEQIGTPAEVYDQPATAFVHSFLGSVNLFRGRVAGQGLGIGEQQLGGPISSQLAQGSAAIAYVRPHELEILPADAPGGISATITRLLPMGPRIRVELRGDGETRGAHYEAELSKEAARAFAPGQGVRLVARHAQLYPDYQI
>NZ_CP007567.1|WP_005332399.1|4630342_4631290_-|HTH-type-transcriptional-regulator-Cbl
MNFQQLRIIREASRRDYNLTEVANALFTSQSGVSRHIRELEEELGLALFIRYGKRLLGMTEPGKELLVIAERILGDADNIRKLASTFANRDSGRLLVATTHTQARYALPRVVKAFREQFPLVQLELRQGSPEEIVRLVQTGEVDIGISSEQLDKSEGVVAFPYYRWHHNIVVPEQHPLTAERELTLAALAHWPIVTYQAGLTGRVRVDEAFAEAGIHPQILLTAQDSDVIKTYVELEMGVGILADMAFDPQRDKGLVQLDGSRLFAPHTAWIGLKQGQFQHNFTWQFIQLCNPELALAEIQARAMSNEPLLDYQI
>NZ_CP007567.1|WP_005327739.1|4650240_4651404_+|competence-protein-CinA
MRIEIISTGDEIVTGLVVDTNAAWLSALLLEQGWQVRRRLTVGDNLADLKAALQESASRAEVVLVCGGLGPTADDLTAQAAAEAFGQPLTLFPDWLATMAERYASRGRTMAQSNTKQAWLPRDCEILDNPVGTACGFVVNHPASHGQSRLFFTPGVPFEFKQMVREQILPRLKALAGEETDTELRRFYTFGISESALSDKLDAAPWPASIELGYRSSMPLIELKLIGHGASAADMDAAEARLLGEITPWLVGQGNEEPAQQILSLLGARPLYLQEGESRGALLAMCHPHPGLEASFSHCLPCELDQLTGCGQEPCLTIGSAGPGGVPLLLCADGQRIGQQVKLSHPDPESARRILAFAALDMLRRHLQGLPVLADYLTLTRTASRID
>NZ_CP007567.1|WP_005327731.1|4651411_4651927_-|metal-dependent-hydrolase
MTAQGHLLFSVTCALLAHKVELTPALAEGSLWHIVPMALASALLPDLDHPQSLLGRQLPWISGPLSRLFGHRGFTHSLLAVGLGIWGLAQFQVSGPLSGVMKDALIVGYLSHLLGDWLTPMGIPLLWPWRRRFRLPGLPLKSGGGYEKAFCLLTLALAGYWVHGNGGLGAF
>NZ_CP007567.1|WP_005327730.1|4652367_4653996_+|DUF342-domain-containing-protein
MTYVCLRIAPGLTDLVQEHHVLALLRLSNCRRYQPLGEGIRQAVTLLNTLLTQPDAPSHPPVPIAQRQDARLLILIDKDQMSASAQITADWGGSSLTLAQLQEAVAASPVKQGVSERLLAAAIKAASEAAPGTRLNPVIALGKAARHGLDTRLERLVETAAERILKPQELDHGRVDMRDLGTLLTVKAGAPLMQRHPATQGIDGFTVTGQVLAARSGKESAMTAGEGTCFSPEDPDLLLATRAGLPCQERAGMRVDEVLSVKQVDIRHGHVEFEGSLLVTGDVMPGMRIRTSGDVVIGGFVEGGYIESGGTITVRNGIIGRKLEGDEYLCHLCAGGEIHASYAQYARLEADGDIHIQSQLSHSYCRSGQDLKVGDSAMRKGHLIGGINIANRLIMAPVLGASAANRTRLQILGGYFSHKEQEQALRQRKQACREQLDKLQDLILRLLQQPSDKRNPETLKKIKAIRTHQLDESKSLDEQLAEAQHALQALMASMDIIATQRLFPGVEVEMAHYHSRVDIEHGPIHFAIRDEQLQLTPYEGQR
>NZ_CP007567.1|WP_005327726.1|4654110_4654920_+|sugar-phosphatase
MYKLIALDMDGTLLNPHGQITPRTHAAIAAARTQGVTVVLTSGRPLEGMTTYLAELGLTGQDDYVICYNGALVQQVADQRILRSQLLTGSDASAIAHLAFELGVNVHGFSVRQGLISPRVSTYTEHESRLIKMPINLVDFATLPADEQIMKVMMIDPEPQLSRAIAQLPAELYERYTVVRSSPYFLEFMNKRSNKGTSVAALAEHLGLDASQVIAVGDAGNDRHMIEYAGLGVAMGNATDEIKALAQHTTARNDEDGVARVIEQFILNA
>NZ_CP007567.1|WP_041206762.1|4655285_4656056_+|gamma-glutamyl-gamma-aminobutyrate-hydrolase-family-protein
MPNPSSHSKPVVLMTMGAQARSGHAYQVMTHKYITPLVEISGCVPLLVPTCCGTADLEQYLDLADGVYLSGAGSNIDPALYGQENLTPEKAQDRDRDLFDIALVRAAIDRGLPLLGICRGMQEINVALGGDILQKVYCEPGYADHREDADDPVEEQYGHSHQVSLVPGSWFADLMGEAQIPVNSLHGQGIKRLGEGLAPLAHAEDGLIEAIHAPGLPQFTLAVQWHPEWKAKENPHSIKLFKAFGDACRQYRQRAG
>NZ_CP007567.1|WP_005327724.1|4656052_4656457_-|hypothetical-protein
MKSVIWLAIPMVLAGCDLFRDHYRMEFRDGSWRDIAISPFSDEARWREGCATGEILVDMTLPLKRGKVVDGREQLLIGGELFELEEARLYRGNGMVLGQAPDHVQRGLKGLDVCRTLRPDRGALPKLKGKGFGD
>NZ_CP007567.1|WP_041205253.1|4656532_4657870_-|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNEPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIEKRPRPSRPRAVKISKTRFPVNRNAAPLK
>NZ_CP007567.1|WP_005330947.1|4657990_4658701_-|HAD-IA-family-hydrolase
MHFYRRWQPVAAISFDLDDTLYDNGPAIARAEQWMLSHLRSEYLATAMLDKPRWLELKRNLLLARPELGQDVSLARQHGIREAMVQGGMTVSLAEQEAERVFAGFLAERSKIAVSESTHRLLTRLAERYPLAVITNGNLDLVQAGLSDYFTLVCKAGAGARMKPAPDMFVQVQQTLGLASGQILHVGDHPETDVLGARLHGFRAAWLNEHRLPWQSLRLLPDVELAALDELDGLLL
>NZ_CP007567.1|WP_180345053.1|4658747_4659671_-|tyrosine-recombinase-XerC
MPPALAGELTAFIEYLRVERQLSPHTRSNYQAHLEAMAAELVRLGVDDWARLEASQVRSLVTRMHKAGLAPRSLATKVSALRSFCDWQVRQGRLPANPARGIVTPKQGRPLPKNLDVDEMYQLLNITDEQDPLAVRDRAIMELMYSSGLRLAELVGLNLADVKLDERQLRVTGKGSRERVLPMGRMAVEWLHKWLKVRPALAGDEGEALFVSKRRQRLSARSVQERLDGWGNKQALNAHVHPHKLRHSFATHMLESSGDLRAVQELLGHADLSTTQIYTHLDFQHLAKVYDSAHPRAKRDPDTPEDE
>NZ_CP007567.1|WP_005330951.1|4659696_4660377_-|DUF484-family-protein
MSELKRQESLLDEATVLEYLARYPEFFQRHGAMLDRIRIPHEHKGTISLVERQLDRQRERIEQLEQEITELMGIASENERIFRVYADLYGELYGCQTLFELSAVMGKAFVQRLRLTGLRLWLSPKKFQLSGPEQRFLADGKQLDQLLGQRLPGTDYYFGRLNQSEKQALFGSDVLVNSVALMRLGDLGVLAFASSDPSHFTPHNDTLLLGQLGRLLQMRLPELVRG

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Crispr_ID: NZ_CP007567_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_12

4728720-4728932

Orphan

I-B,III-A,III-B

Consensus_repeat	Method
GGTCTTCCCCACGCCCGTGGGGGTGTTTC	CRT
TTCCCCACGCCCGTGGGGGTGTTTC	CRISPRCasFinder
GTCTTCCCCACGCCCGTGGGGGTGTTTCT	PILER-CR

3 spacers

The CRISPR arrays of NZ_CP007567_12

>merge|NZ_CP007567|12|4728720-4728932|CRT,CRISPRCasFinder,PILER-CR
GCCATTCCCCACGCCCGTGGGGGTGTTTCCGACATTGCCGCCAGAGAGTGCCGTGAGTGCGGGTCTTCCCCACGCCCGTGGGGGTGTTTCTTGGTCATACACTAGCGTTGCCACCATCACACCGTCTTCCCCACGCCAGTGGGGGTGTTTCCGAAATCGGTCTCGATGAAACCGGCGATGGTTGGTCTTCCCCACGCCCGCGGGGGTGTTTCT

>NZ_CP007567|12|1|4728720-4728931|CRT
GCCATTCCCCACGCCCGTGGGGGTGTTTC	CGACATTGCCGCCAGAGAGTGCCGTGAGTGCG
GGTCTTCCCCACGCCCGTGGGGGTGTTTC	TTGGTCATACACTAGCGTTGCCACCATCACAC
CGTCTTCCCCACGCCAGTGGGGGTGTTTC	CGAAATCGGTCTCGATGAAACCGGCGATGGTT
GGTCTTCCCCACGCCCGCGGGGGTGTTTC

>NZ_CP007567|12|12|4728724-4728931|CRISPRCasFinder
TTCCCCACGCCCGTGGGGGTGTTTC	CGACATTGCCGCCAGAGAGTGCCGTGAGTGCGGGTC
TTCCCCACGCCCGTGGGGGTGTTTC	TTGGTCATACACTAGCGTTGCCACCATCACACCGTC
TTCCCCACGCCAGTGGGGGTGTTTC	CGAAATCGGTCTCGATGAAACCGGCGATGGTTGGTC
TTCCCCACGCCCGCGGGGGTGTTTC

>NZ_CP007567|12|1|4728782-4728932|PILER-CR
GTCTTCCCCACGCCCGTGGGGGTGTTTCT	TGGTCATACACTAGCGTTGCCACCATCACACC
GTCTTCCCCACGCCAGTGGGGGTGTTTCC	GAAATCGGTCTCGATGAAACCGGCGATGGTTG
GTCTTCCCCACGCCCGCGGGGGTGTTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_041206782.1\|4740603_4741410_-\|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|143596
NZ_CP007567.1\|WP_081805831.1\|4726508_4726694_+\|AlpA-family-phage-regulatory-protein	unknown	unknown	gnl\|CDD\|225848
NZ_CP007567.1\|WP_005326732.1\|4717924_4718101_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_041205297.1\|4732210_4733485_-\|IS4-like-element-ISApu2-family-transposase	unknown	unknown	gnl\|CDD\|376573
NZ_CP007567.1\|WP_005326727.1\|4712299_4715995_-\|methionine-synthase	unknown	unknown	gnl\|CDD\|236539
NZ_CP007567.1\|WP_041206779.1\|4730706_4731228_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
NZ_CP007567.1\|WP_005331561.1\|4734937_4736254_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NZ_CP007567.1\|WP_099993964.1\|4721518_4722535_+\|IS5-like-element-IS5-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_CP007567.1\|WP_041206781.1\|4739041_4740490_-\|metalloprotease-TldD	unknown	unknown	gnl\|CDD\|182685
NZ_CP007567.1\|WP_005331562.1\|4736385_4737102_+\|MarC-family-NAAT-transporter	unknown	unknown	gnl\|CDD\|236814
NZ_CP007567.1\|WP_010674210.1\|4718370_4719984_-\|IS1634-like-element-ISAs25-family-transposase	unknown	unknown	gnl\|CDD\|227708
NZ_CP007567.1\|WP_099369027.1\|4726749_4727766_+\|IS5-like-element-IS5-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_CP007567.1\|WP_041206780.1\|4737262_4737466_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_041206775.1\|4716197_4717475_+\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NZ_CP007567.1\|WP_005331560.1\|4734093_4734783_-\|ATPase	unknown	unknown	gnl\|CDD\|238952
NZ_CP007567.1\|WP_049832223.1\|4727935_4728643_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|366760
NZ_CP007567.1\|WP_148304727.1\|4725625_4726405_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_010674210.1\|4723074_4724688_+\|IS1634-like-element-ISAs25-family-transposase	unknown	unknown	gnl\|CDD\|227708
NZ_CP007567.1\|WP_005331711.1\|4731448_4731712_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP007567.1\|WP_049832204.1\|4737637_4738975_+\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_041206782.1\|4740603_4741410_-\|carbon-nitrogen-hydrolase-family-protein	gnl\|CDD\|143596	cd07572, nit, Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases). This subgroup includes mammalian Nit1 and Nit2, the Nit1-like domain of the invertebrate NitFhit, and various uncharacterized bacterial and archaeal Nit-like proteins. Nit1 and Nit2 are candidate tumor suppressor proteins. In NitFhit, the Nit1-like domain is encoded as a fusion protein with the non-homologous tumor suppressor, fragile histidine triad (Fhit). Mammalian Nit1 and Fhit may affect distinct signal pathways, and both may participate in DNA damage-induced apoptosis. Nit1 is a negative regulator in T cells. Overexpression of Nit2 in HeLa cells leads to a suppression of cell growth through cell cycle arrest in G2. These Nit proteins and the Nit1-like domain of NitFhit belong to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), this subgroup corresponds to class 10.	2.39253e-141
NZ_CP007567.1\|WP_081805831.1\|4726508_4726694_+\|AlpA-family-phage-regulatory-protein	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	2.18122e-10
NZ_CP007567.1\|WP_041206775.1\|4716197_4717475_+\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	9.42793e-70
NZ_CP007567.1\|WP_041205297.1\|4732210_4733485_-\|IS4-like-element-ISApu2-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	8.31853e-17
NZ_CP007567.1\|WP_005326727.1\|4712299_4715995_-\|methionine-synthase	gnl\|CDD\|236539	PRK09490, metH, B12-dependent methionine synthase; Provisional.	0
NZ_CP007567.1\|WP_041206779.1\|4730706_4731228_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.04977e-29
NZ_CP007567.1\|WP_005331561.1\|4734937_4736254_+\|MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.59392e-85
NZ_CP007567.1\|WP_099993964.1\|4721518_4722535_+\|IS5-like-element-IS5-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	3.65198e-54
NZ_CP007567.1\|WP_041206781.1\|4739041_4740490_-\|metalloprotease-TldD	gnl\|CDD\|182685	PRK10735, tldD, protease TldD; Provisional.	0
NZ_CP007567.1\|WP_005331562.1\|4736385_4737102_+\|MarC-family-NAAT-transporter	gnl\|CDD\|236814	PRK10995, PRK10995, MarC family NAAT transporter.	9.27811e-100
NZ_CP007567.1\|WP_010674210.1\|4718370_4719984_-\|IS1634-like-element-ISAs25-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	2.45339e-57
NZ_CP007567.1\|WP_099369027.1\|4726749_4727766_+\|IS5-like-element-IS5-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	3.22647e-54
NZ_CP007567.1\|WP_005331560.1\|4734093_4734783_-\|ATPase	gnl\|CDD\|238952	cd01994, Alpha_ANH_like_IV, This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily of proteins is predicted to bind ATP. This domainhas a strongly conserved motif SGGKD at the N terminus.	2.68332e-51
NZ_CP007567.1\|WP_049832223.1\|4727935_4728643_+\|ATP-binding-protein	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	3.87716e-51
NZ_CP007567.1\|WP_010674210.1\|4723074_4724688_+\|IS1634-like-element-ISAs25-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	2.45339e-57
NZ_CP007567.1\|WP_049832204.1\|4737637_4738975_+\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	1.48368e-31

>NZ_CP007567.1|WP_049832223.1|4727935_4728643_+|ATP-binding-protein
MKQALNQQQAQSMLYLDMGFEERLQLLLSHELVQREQRKTNRLEKQARFRLAGQVEQLDYRAGRGVSQAQIRQLLEGHWLSHQQNLLLTGAAGCGKSYLACALGRYFIRQGVGVRYYRLKTLLEEMRLAQADGSYPKLLEQVSHIGMLILDDWGMEMLDASERSNLLEIIDTRYGKVSTIVASQLPVEKWYGMIGEATFAEAILDRLIHRAVRVTLTGESMRKQGANLTEADQAE
>NZ_CP007567.1|WP_099369027.1|4726749_4727766_+|IS5-like-element-IS5-family-transposase
MFVIWSHGTGFIMSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAIEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPQMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRAKVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH
>NZ_CP007567.1|WP_081805831.1|4726508_4726694_+|AlpA-family-phage-regulatory-protein
MISQKILSITAVCELVGRNRRTLWAWVRDGVFPQPIKVHGKTVGWPESVYQNWLAVQMADK
>NZ_CP007567.1|WP_148304727.1|4725625_4726405_+|hypothetical-protein
MTTIGLSYSLVKISTKCAPALMFYRFSYGGVTFPLTMMAKASGLWAVGHNFTKQLESYGAVDFRSFFLKHGYLLSIDNPIEGFQVSIVPVTSIEEPAVPDQRILPEDLWLTHESIQRLLGHKDQRAANQYLQPLSKPQRYSPKKHAMICFLTELLMERDDALSAITFGQHPLISSHYHQLVTELSETLQCPTEVLIRQLLSRCAHSSIAFLFLTNKQFEEWSNAAIAEAIRTLMSSRKRDQIQSQLANIDKNTIQHWLN
>NZ_CP007567.1|WP_010674210.1|4723074_4724688_+|IS1634-like-element-ISAs25-family-transposase
MAAPAISIRNLDHLGLVAALCQELGIARMIDALLPKTPPFKVSHGEALVAMIVNGLGFHSSTLHMFPQFFANKPVERLIGPGICADDLNDDVLGRCLDALFEADVSALYQVMAAQVVERLGLKSTAVHLDITSFHVDGAYDCADGDLVGKLQLVRGYSRDHRPELNQVILELICENQAGLPVYMQALSGNSNDTKAFAQTVRRHLSSLKAAQECRYLVGDAALYCADTLQLLAQQQQLFVTRVPVTLNEAKQAVATIGAQPLTALGNGYHGRWQHANYAGVAQRWLLVRSEQASHREQQTLAKNLLKDSTRELKAFAKLCARRFACEADAQAELSCFTASLMLLQLDAEVVGEPVYTGRGRPKRGEEPIGHQFQITGLAATSLACVEEARNQTGVFILATNDHSDTLTMAELLATYKAQQNVERGFRFLKSPEFLTSSLYLKKPERIEALLMVMTCSLMIYAALEHRIRQGLVEQNRSVADMKKKPTQQPTARWIFLRFGGIHEYRLGEAPPQVTELTGDQQIILEVLGERYRQIYS
>NZ_CP007567.1|WP_099993964.1|4721518_4722535_+|IS5-like-element-IS5-family-transposase
MFVIWSHGTGFIMSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAIEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRAKVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH
>NZ_CP007567.1|WP_010674210.1|4718370_4719984_-|IS1634-like-element-ISAs25-family-transposase
MAAPAISIRNLDHLGLVAALCQELGIARMIDALLPKTPPFKVSHGEALVAMIVNGLGFHSSTLHMFPQFFANKPVERLIGPGICADDLNDDVLGRCLDALFEADVSALYQVMAAQVVERLGLKSTAVHLDITSFHVDGAYDCADGDLVGKLQLVRGYSRDHRPELNQVILELICENQAGLPVYMQALSGNSNDTKAFAQTVRRHLSSLKAAQECRYLVGDAALYCADTLQLLAQQQQLFVTRVPVTLNEAKQAVATIGAQPLTALGNGYHGRWQHANYAGVAQRWLLVRSEQASHREQQTLAKNLLKDSTRELKAFAKLCARRFACEADAQAELSCFTASLMLLQLDAEVVGEPVYTGRGRPKRGEEPIGHQFQITGLAATSLACVEEARNQTGVFILATNDHSDTLTMAELLATYKAQQNVERGFRFLKSPEFLTSSLYLKKPERIEALLMVMTCSLMIYAALEHRIRQGLVEQNRSVADMKKKPTQQPTARWIFLRFGGIHEYRLGEAPPQVTELTGDQQIILEVLGERYRQIYS
>NZ_CP007567.1|WP_005326732.1|4717924_4718101_+|hypothetical-protein
MMKAVQTHKPLRRSKPINLPVQEHDYDAFLIQFSTRSSGGFAISCDGIPGEFSIEELN
>NZ_CP007567.1|WP_041206775.1|4716197_4717475_+|sodium:proton-antiporter
MSVYYTLCFLAALAIFIAFANQYVVKIQTTIAITAGSMLISALMVLFGKLGWFNLEPLAVETMESIDFQNFLLKGILGFLLFAGGLGINLKALRSQKWEITILSIAATLLSTFIIGYGFWFIAKLLGWELPLVYCMLFGALISPTDPIAVLAIVKKMKAPPQIAIQIEGESLFNDGVGLVIFATVFAVAFGGVEPTFGSVAGLFLHEALGGILFGAVLGLIAHVMISATDDGSLELLLTLCIPTAGFAFANMIGVSGALAMVVTGIMIGNWTRQSGFSEQSRHHLDHFWELMDQFLNALLFLLIGLALVLLDLAWQDWILLVIAVPLCLAARFISVSLPYVAFRKFRSYNRFSVRILTWGGLRGGLAMAMALALPSGVMVLPEQGVDLREVILVMTYSVVMFSIVVQGMTITPMITAAKKASGDY
>NZ_CP007567.1|WP_005326727.1|4712299_4715995_-|methionine-synthase
MSSIESSKKSDVTKKLEACLKERILIIDGAMGTMIQGYRLGEADYRGERFADWHTDIKGNNDLLVLTRPAVIREIHDQYCAAGADILETNTFNATRIAMADYEMEAFSAEINREAARLARAVADEWTAKDPARPRFVAGVLGPTNRTCSISPDVNDPGKRNVTYDQLVAAYTESTHALIEGGADIILIETIFDTLNAKAAAFAVDLVFEALGYSLPVMISGTITDASGRTLSGQTTEAFYHSLRHVKPVSFGLNCALGPDELRQYVEELSRISESCVSAHPNAGLPNAFGEYDLDAGEMAEHIREWAQSGFLNLVGGCCGTTPTHIRAMSDAVAGIKPRALPELPVACRLSGLEPLIITSESMFVNVGERTNVTGSAKFKRLIKEGLYDEALDVAKQQVESGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPVMIDSSKWEVLEAGLKCVQGKPVVNSISMKEGEDKFIEQAKLLRRYGAAVIVMAFDEVGQADTRARKFEICQRAYRILVDRVGFPPEDIIFDPNIFAVATGIDEHNNYAVDFIEAVKDIKTHLPHAMISGGVSNVSFSFRGNEPVREAIHAVFLYHAIQNGMDMGIVNAGQLAIYEDIPAELKAKVEAVVLNLSDSATEDLLAIAEKYRGAGAQAEDPRDQEWRSWPVGKRLEHALVKGITDFIEEDTEEARAGADKPLHVIEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKRAVAYLQPYIEAEKSGGSSNGKIVMATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVSCETILKTAREVGADIIGLSGLITPSLDEMVHVAKEMERQGFKLPLLIGGATTSKAHTAVKIEQNYSEPVVYVSNASRAVGVAQSLLNPELKPAFVARIDKEYEIARDQHARKQPRSKPVSLAHARANRHQLDWVGYEPPAPREPGVQTFENVPVSVLRPYIDWTPFFLSWELAGKYPRILEDEIIGEEATKLFADANAMLDQLEKDQSVRCAGIIGLFPANGVGDSIEVYSDESRTEVIKVLHHLRQQSEKQGFPNYCLADYVAPRESGKPDWIGAFAVTGGIGEEAIAQAYKADHDDYNAILIQAVCDRLAEAFAEYLHEQVRKRHWGYAPDEALSNEELIRENYQGIRPAPGYPACPEHTEKGSIWELLDVEQAIGMQLTESYAMWPGAAVSGWYFSHPDSKYFAVAQIQPDQVEDYAQRKGMTLVEAERWLGPNLH
>NZ_CP007567.1|WP_041206779.1|4730706_4731228_-|GNAT-family-N-acetyltransferase
MIFSERLILRELNTDDAPFILELLNDPDFHRYIGDRGIRTLDDAENYIQQGPAVSYAQHGHGLYLVMRREDEAKLGICGLIKRDTLPCEDIGYAFLPAWRGQGYGIEAAQAAIKDGRERLGIERVIAIVTPGNERSVALLGKLGLVRSRLVRLSEDADECLLLEAADTQACTV
>NZ_CP007567.1|WP_005331711.1|4731448_4731712_+|hypothetical-protein
MTDTTEFFDEQTLLEMVDNQLADGHPLQVKATLMRLVMKGTPRDEALQYIACALGAELMAMEAEQGPFNLTRYAEFLDCLPEMPWAE
>NZ_CP007567.1|WP_041205297.1|4732210_4733485_-|IS4-like-element-ISApu2-family-transposase
MTIINATQYLKQLLSSSELNRIGKFTGFCQRLRDIQPARLLPALLSGLGCDKVDGIAGLHRHFNALQLHDTDQIAYKPFHNQLRKQGFPLFMRALVERAIALRLKECLPDAHGLAGFEQVLLQDGSSFALHPQLAEHFPGRFNKHSPAAVECHMTMSLLDQSPISMSITADTESERKHLPAANSLNNKLLLADAGYISREYFADVTKAKGSYLVRGSQNLNPKVQAAYRQDGREMPKLLGKKLKDIDRRSCRAEVLDLDVSSGKYKYRLIRRWFAEEKRFCIWMTNLPRERWPAEKVMALYRCRWQIELLFKELKSHNRLKAFATRQKAIAEGLIWASLLALLVKRRLALTLIGSAELSMLKIAKNSALWLMPILASIIHGAWQEITEKLEWAMVYLSKNGKKSRQRRSKQNNTLDGIINSLAA
>NZ_CP007567.1|WP_005331560.1|4734093_4734783_-|ATPase
MTKKKVLLSWSSGKDSAWALHRLRQDPAIEVVGLFTTLNQAFERVAMHGVRKQLLTEQAACVGLPLHCIDLPWPSSNEDYGRIMTGFITEVLAMGIRHMAFGDLFLEDVRAYREKQLTGTGIAPLFPLWGSDTSELAQEMMAAGLRARISTLDPKKLDMSLGGHEFDEALLAALLAALPDGVDPCGENGEFHTLAFDGPMFLRPLAIRVGETVVRDGFVFTDLLPDEAP
>NZ_CP007567.1|WP_005331561.1|4734937_4736254_+|MFS-transporter
MTTVSTHHDHNRPLNRQDYKTLSLAALGGALEFYDFIIFVFFAVVIGELFFPADIPEWLRQFQTFGIFAAGYLARPLGGIIMAHFGDLIGRKRMFTLSIILMALPTLLIGLLPTYATLGIAAPLLLLLLRILQGAAIGGEVPGAWVFVAEHVPARRVGVACGTLTAGLTAGILLGSLVATAINRGMSPIEVSEWGWRLAFVLGGVFGIVAMYLRRWLHETPVFAEMQANKALAEELPLKTVLREHKGSVIVSMLLTWLLSAGIVVVILMTPTYLQKVHGISPTDALTANSLAIVALTLGCIFYGRLIDSLGSGPTFVLGSLLLAGATYAFYHSLAAGMDQLIPLYMLAGFAVGIVGAVPYVMVNAFPPVVRFSGLSFSYNVAYAIFGGLTPMLVTLWMKNDVLAPSHYVVSLAGLGFVLGLWLWLRQRTRRQVTPQTA
>NZ_CP007567.1|WP_005331562.1|4736385_4737102_+|MarC-family-NAAT-transporter
MFFQVVFIALLALLPMVNPPTTATLLLGLSKGMSREHIRRQINLAAIYLFATLCVSFFIGSSILDLFGISIPGLRLAGGLIIAFIGFRMLFPAPSQAAGVDINQSIAFVPLTMPSMCGPGTMALVISGAAQIAELPDEYNRFVIYAAMVTAFALMSLLSWGVLKLADPVCKILGATGIDAMTRIMGFLLVCMGMQFCINGIKEVAQDPVFHGATTVQTAPALSHAPGAPDHLPAPHQP
>NZ_CP007567.1|WP_041206780.1|4737262_4737466_+|hypothetical-protein
MEEMLTEIGSYSLFHEYLNVVGAASPALTRIKSRWEYKRSDRLVAQIRIDPQGHARFYIDARAISVN
>NZ_CP007567.1|WP_049832204.1|4737637_4738975_+|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNEPISEVARHLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPEDHWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIRSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIEKRPRPSRPRAVKISKTRFPVDRNAAPLK
>NZ_CP007567.1|WP_041206781.1|4739041_4740490_-|metalloprotease-TldD
MSLLSQVSASLLAPNDLDEGRLQQLLGSLMSHQVEFGDLYFQRSWHESWMLEDGIVKDGSYNIDQGVGVRAVSGEKTGFAYSDELSLLALQQSVTAARGIAAAGAQGKVKAWARTEANLLYPAMDPLQTLDKQQKIALLEQMDKFARSLDPAINQVMASISGVYEEILVAATDGTLAADVRPLVRLSVTVIAEKGDRRERGSAGGGGRFGYDYFLELDGLENRAFGYVREAVRQALVNLEAIDAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRKGSSAFAGRIGEQVASRHCTIVDDGTLVGRRGSVSIDDEGTPGGYNVLIENGILKGYLQDKQNARLMGVPLTGNGRRESYAALPMPRMTNTYMLAGQHDPAEIIASVKKGIYAPNFGGGQVDITSGKFVFSASEAYLIEDGRITAPIKGATLIGNGPEAMSQVSMVGSDLALDRGVGVCGKEGQSVPVGVGQPTLKLDQLTVGGTS
>NZ_CP007567.1|WP_041206782.1|4740603_4741410_-|carbon-nitrogen-hydrolase-family-protein
MWLAAIQLISGRHWQDNRAQIAAELAALPKERPLLVLLPENFALFGERQGYLDGAEALGEGPIQTQLAAWAREHGIWLVAGAMPTTIAGSDHIHTSSLVFDPEGALRGHYHKIHLFDVDVADNHGRYRESETFSPGQECVVLDSPFGPLGLSICYDLRFPELYRRLARAGARVLLVPAAFTAVTGEAHWEPLLRARAIENQCYVVAANQGGTHETGRQTWGHSMVIDPWGRVLACQDSGPATVLVKMEPGLVDELKRTMPVLQHARLL

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Crispr_ID: NZ_CP007567_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP007567_13

4772857-4772959

Orphan

Consensus_repeat	Method
GCGTTCTTCTCAAGCTGGCGCACACGCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP007567_13

>merge|NZ_CP007567|13|4772857-4772959|CRISPRCasFinder
GCGTTCTTCTCAAGCTGGCGCACACGCTCGGCGAATGCCCTCAGGCGACCATCGCATCCTTCAGCTTCTTGAGAGCGTTCTTCTCAAGCTGACGCACACGCTC

>NZ_CP007567|13|13|4772857-4772959|CRISPRCasFinder
GCGTTCTTCTCAAGCTGGCGCACACGCTC	GGCGAATGCCCTCAGGCGACCATCGCATCCTTCAGCTTCTTGAGA
GCGTTCTTCTCAAGCTGACGCACACGCTC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP007567.1\|WP_005323433.1\|4775168_4775840_-\|cell-division-ATP-binding-protein-FtsE	unknown	unknown	gnl\|CDD\|225438
NZ_CP007567.1\|WP_005331214.1\|4768486_4769722_-\|imidazolonepropionase	unknown	unknown	gnl\|CDD\|236478
NZ_CP007567.1\|WP_041206790.1\|4772034_4772694_-\|carbonate-dehydratase	unknown	unknown	gnl\|CDD\|238448
NZ_CP007567.1\|WP_099993964.1\|4760004_4761021_-\|IS5-like-element-IS5-family-transposase	unknown	unknown	gnl\|CDD\|225581
NZ_CP007567.1\|WP_005331224.1\|4761256_4762786_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NZ_CP007567.1\|WP_041205242.1\|4769857_4771195_-\|IS4-like-element-ISAeme15-family-transposase	unknown	unknown	gnl\|CDD\|379017
NZ_CP007567.1\|WP_005331218.1\|4765785_4767489_-\|urocanate-hydratase	unknown	unknown	gnl\|CDD\|235448
NZ_CP007567.1\|WP_005323425.1\|4771318_4772023_-\|histidine-utilization-repressor	unknown	unknown	gnl\|CDD\|188194
NZ_CP007567.1\|WP_005331222.1\|4762952_4764050_+\|calcium:proton-antiporter	unknown	unknown	gnl\|CDD\|182580
NZ_CP007567.1\|WP_005323432.1\|4774215_4775169_-\|cell-division-protein-FtsX	unknown	unknown	gnl\|CDD\|182910
NZ_CP007567.1\|WP_041206789.1\|4767555_4768494_-\|formimidoylglutamase	unknown	unknown	gnl\|CDD\|237500
NZ_CP007567.1\|WP_005331220.1\|4764251_4765784_-\|histidine-ammonia-lyase	unknown	unknown	gnl\|CDD\|236484

Protein	Function_ID	Function_description	E-value
NZ_CP007567.1\|WP_005323433.1\|4775168_4775840_-\|cell-division-ATP-binding-protein-FtsE	gnl\|CDD\|225438	COG2884, FtsE, Predicted ATPase involved in cell division [Cell division and chromosome partitioning].	6.24883e-125
NZ_CP007567.1\|WP_005331214.1\|4768486_4769722_-\|imidazolonepropionase	gnl\|CDD\|236478	PRK09356, PRK09356, imidazolonepropionase; Validated.	0
NZ_CP007567.1\|WP_041206790.1\|4772034_4772694_-\|carbonate-dehydratase	gnl\|CDD\|238448	cd00883, beta_CA_cladeA, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	5.98995e-123
NZ_CP007567.1\|WP_099993964.1\|4760004_4761021_-\|IS5-like-element-IS5-family-transposase	gnl\|CDD\|225581	COG3039, COG3039, Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair].	3.65198e-54
NZ_CP007567.1\|WP_005331224.1\|4761256_4762786_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.80098e-81
NZ_CP007567.1\|WP_041205242.1\|4769857_4771195_-\|IS4-like-element-ISAeme15-family-transposase	gnl\|CDD\|379017	pfam13006, Nterm_IS4, Insertion element 4 transposase N-terminal. This family represents the N-terminal region of proteins carrying the transposase enzyme, DDE_Tnp_1 (that was Transposase_11), pfam01609, at the C-terminus. The full-length members are Insertion Element 4, IS4. Within the collection of E.coli strains, ECOR, the number of IS4 elements varies from zero to 14, with an average of 5 copies/strain.	6.74489e-32
NZ_CP007567.1\|WP_005331218.1\|4765785_4767489_-\|urocanate-hydratase	gnl\|CDD\|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0
NZ_CP007567.1\|WP_005323425.1\|4771318_4772023_-\|histidine-utilization-repressor	gnl\|CDD\|188194	TIGR02018, Histidine_utilization_repressor, histidine utilization repressor, proteobacterial. This model represents a proteobacterial histidine utilization repressor. It is usually found clustered with the enzymes HutUHIG so that it can regulate its own expression as well. A number of species have several paralogs and may fine-tune the regulation according to levels of degradation intermediates such as urocanate. This family belongs to the larger GntR family of transcriptional regulators. [Energy metabolism, Amino acids and amines, Regulatory functions, DNA interactions].	7.60347e-96
NZ_CP007567.1\|WP_005331222.1\|4762952_4764050_+\|calcium:proton-antiporter	gnl\|CDD\|182580	PRK10599, PRK10599, sodium-potassium/proton antiporter ChaA.	1.0002e-98
NZ_CP007567.1\|WP_005323432.1\|4774215_4775169_-\|cell-division-protein-FtsX	gnl\|CDD\|182910	PRK11026, ftsX, cell division ABC transporter subunit FtsX; Provisional.	1.13138e-77
NZ_CP007567.1\|WP_041206789.1\|4767555_4768494_-\|formimidoylglutamase	gnl\|CDD\|237500	PRK13776, PRK13776, formimidoylglutamase; Provisional.	0
NZ_CP007567.1\|WP_005331220.1\|4764251_4765784_-\|histidine-ammonia-lyase	gnl\|CDD\|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0

>NZ_CP007567.1|WP_041206790.1|4772034_4772694_-|carbonate-dehydratase
MKLLNDLFTNNREWAERIKAEDPEFFATLSAQQAPEYLWIGCSDSRVPANQLMGLLPGDVFVHRNVANLVVHTDFNCLSVLQYAVEVLKVKHIIVCGHYGCGGVKAAMQNQELGLIDNWLRNIKDVYFKYGEELEAIEDEHERFDYLCELNVAEQVANVCHTTIIQNAWRKGQELAVHGWIYGIKDGLLHDLDLCISGPDQIPDVYRAWPDMRPPHRRR
>NZ_CP007567.1|WP_005323425.1|4771318_4772023_-|histidine-utilization-repressor
MAPALYLQIKQHILDGIRERHYQAGDRIPTEAALCEQFAVSRMTVNKALRELVAEGWLNRTAGSGSFVADRRAESPLLAIRNIADEIAERGSQYSARVIRLQRQAADEKVAVRLGLRVGAPTFHSLIVHQADGEPLQLEERFVDAERLPGYGEQDFTRQTPNSYLMEICPLSEMEHVVEAVLPSAGEAGLLQVRVDTPCLLLHRRTWSDGFLVSYARLLSPGSRYKLSSKTRLT
>NZ_CP007567.1|WP_041205242.1|4769857_4771195_-|IS4-like-element-ISAeme15-family-transposase
MSIANDLNDVVEASGDMLARLAIFADHIPDEWITAAAALSEKATIRRRRLPSDMVLWLVVGMAFFRNEPISEVARRLNICAEGLANDALLADSALSQARQRLGKQPLEWLFKQCADVWGRERYPQDQWHGLQVFAIDGALFRTQDMPELRAHFGSGNTSTNRQTPYPMLRLVTLMNVRSHVIANAAISPYRKGEIPLASEFIHSLPDKSVTLLDKGFFGADLLLRIQAEDTDRHWLIPERKGLVYTELERYGDGDRLLQMTVSPQARKKNPALPTHWQVRAVTYEVAGKEKTVFTSLPVARFSAAQVATLYHERWEIELGYRDIKSAMQHNAITLRSKKVDLVYQELWGLLLGYNLVRREASQAAVAHQRAPNEVSFKFACQFIANQMAVMAGALSPAHTPRRLAELRGCIGVMFIEKRPRPSRPRAVKISKTRFPVDRNAAPLK
>NZ_CP007567.1|WP_005331214.1|4768486_4769722_-|imidazolonepropionase
MNKELLNCERVWLNVTPATLRSDLADYGLLEPHALGVHEGRIHALVPMQDLKGPYPAHWRDMKGRLVTPGLIDCHTHLIFAGSRAEEFELRQKGVPYAEIARKGGGILSTVRATRAASEDLLYELALPRIKSLIREGVTTVEIKSGYGLTLADELKMLRVARRLGEALPIRVKTTLLAAHAVPPEYRDDPDSWVETICQEIIPAAAEAGLADAVDVFCEHIGFSLAQTEQVYLAADQYNLAVKGHMEQLSNLGGSTLAANFGALSVDHLEYLDQDGIQALAHRGVVATLLPTAFYFLKETKLPPVTALRKAGVPMAVSSDINPGTAPIVSLRMAMNMACTLFGLTPVEAMAGVTRHAARALGEQERLGQLRVGMQADFLIWNCAHPSEISYLIGVDQLVSRVLSGEETLHG
>NZ_CP007567.1|WP_041206789.1|4767555_4768494_-|formimidoylglutamase
MDKFNMADMSVWQGRQDPEDGELALRWHNKVQPWQADSEPGVVLLGFACDEGVRRNKGRVGAAAAPLAIRKLLANTAWHLGRPVHDGGDLACEDGDLDAAHDRLAERVASALDLGHFPLVLGGGHEVAFGCWSGLNRHLGGKGRVGIINFDAHFDLRMKQELASSGTPFFQIAEQCAAQGTTFHYACLGVAETANTQALFARANELGVWHVLDEEMTPADLPELLNGLDAFVARCDHLYLTLDLDVLPAAVMPGVSAPAARGVELAVIEPLIAHIRASGKLRLADLAEYNPSLDLDNRSARVAARLVHQLTK
>NZ_CP007567.1|WP_005331218.1|4765785_4767489_-|urocanate-hydratase
MSVQHQDPRHDPNRVIRAPRGTELTAKSWLTEAPLRMLMNNLDPEVAEHPQSLVVYGGIGRAARNWACYDKIVEVLTRLEDDQTLLVQSGKPVGVFQTHKDAPRVLIANSNLVPHWANWEHFNELDKKGLMMYGQMTAGSWIYIGTQGIVQGTYETFFAVANQHFNGSPAGRWILTGGLGGMGGAQPLAATMAGFSMIAVECDETRIDFRLKTRYVDKKAHSLDEALAMVEEAKQSGTAVSVGLLGNAADVFAELVARGITPDVVTDQTSAHDPIHGYLPQGWSVAQWRELQKSAPQEVNQAARHSMARQVEAMLTLQARGAATLDYGNNIRQMALEEGVKNAFDFPGFVPAYIRPLFCEGIGPFRWVALSGDPEDIYKTDQKVKELIPDDPHLHNWLDMARERIAFQGLPARICWVGVKDRVRLGLAFNEMVKNGELKAPVVIGRDHLDSGSVASPNRETESMMDGSDAVSDWPLLNALLNTAGGATWVSLHHGGGVGMGFSQHSGVVIVCDGTDDAAKRVGRVLRNDPATGVMRHADAGYEIAINCAHEAKLDLPMLNTAGKGAK
>NZ_CP007567.1|WP_005331220.1|4764251_4765784_-|histidine-ammonia-lyase
MFELNLQPGKLCLATLRRVSREPVHVSLDPAALAGIHASAAVVTKVIEQNRVVYGINTGFGLLANTRIPVEQLDELQRSIVLSHAAGIGEYMDDATVRLMMVLKVNSLARGFSGIRLTVLEALMTLINAEVYPVVPKKGSVGASGDLAPLAHMSCLLIGEGKARHKGELIDAATALKIAGLEPIALAPKEGLALLNGTQASTAFALEGLFHAEDLFAGAITIGAMSVEAALGSRRPFDARIHEVRGQRGQIDAAACYRHLLVDGSEIGMSHHNCEKVQDPYSLRCQPQVMGACLTQIRHAAEVLVCEANAVSDNPLVFAEDEEILSGGNFHAEPVAFAADNLALAIAEIGSLSERRMALLIDSRMSGLPAFLVNNGGVNSGFMIAQVTSAALASENKTLAHPASVDSLPTSANQEDHVSMATFAGRRLADMAENTRGILAVELLAAAQGLDFRAPLRSTELIELAKGRLREEVSFYDKDRYFSPDIEAAAALLGAASYNDLIPAGVLPSL
>NZ_CP007567.1|WP_005331222.1|4762952_4764050_+|calcium:proton-antiporter
MKSFIRQEIALPVGLLTLLFFKTLGRDLLTEATPLAVYLPVSLTLLAIVTWAIFSVVRHSDALAIKLGEPFGTLILTLSVISLEVVMISSVMLTGEPNPTMARDTMFAVVMLVTNGLVGFTLLFGGWRYHTQNFNLDGVKSYLVAIIPLALLCLVLPNFTRGGTLGSMSSAMSWMLIIISVLLYGVFLLIQTRSHSHFFVDSDHEDHEDHHGILRSNVYHTLLLLAYLVVVILLAKTLAIPINYGVHVMEAPAALGGFIVACIVLAPEAVGAIKAAFNNQLQRAMNLYFGSVLATIALTVPSVLFIGALLGQEVRLGLDAANMVLLITTLMVCKVTFSSGRTHALHGATHLVLFVVYLFLMFEHE
>NZ_CP007567.1|WP_005331224.1|4761256_4762786_+|EAL-domain-containing-protein
MRRASPFWISLLLLCLPVLASLPLSQLLGNPLTHQLLQQKKAQIEAALTARHKALDDNIRTQLSRFAFDCGPEDMALLRDPRFYNSHIRLQGILLASGRGCSSLGLDLPFTLAELPPYPEQEQFGLAATQARFNTEQEVVAYFRKGDHVAYWVLNNSWSHDQLQSPCPGCFYLEFGQQSPGKVTPLFPRGDKSIKQEPGNQSLSFFDADPQIRQTLWAGKALEEYAKQQARHYGLLYGGALGLLLVAAYWVLRNYRRSLKGLLQAGLVRREFIPFYQPIVDSRSRKVVGFEALLRWQRGRELVPPGTFIDYAEEQGLILPMTEQLLERVIADLPWLEPTQWVSVNIVAAHLEQPHLRPLLQRHDWPSPARLTFELTERKPITDIKAAMGEIAQLQEKGYHFKLDDFGTGYGGFAYLQRLGIRQIKIDKMFVDTIGTDDLKRTLLDSIIAFGHESDMEMIAEGVETLEQVDYLHRHGVHLIQGYVYARPMALHKLKIWLLAWRQSQPGGQ
>NZ_CP007567.1|WP_099993964.1|4760004_4761021_-|IS5-like-element-IS5-family-transposase
MFVIWSHGTGFIMSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAIEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRAKVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH
>NZ_CP007567.1|WP_005323432.1|4774215_4775169_-|cell-division-protein-FtsX
MAIVRHKQPPLRRLMMYGVDHVRQAFASLGELWRNPLASLMTLAVLGVSLALPSCFHVLLKNAEVVEGSWQTSSQISLYLRKDLPEQSILDMKQRILLYPEVESVTYMNRDEALKEFREISGFGDALDYLDSNPLPPVLSVIPDPRWQNPEGAAELLAKLENEPGIEQGKLDLQWLTRLQGIMNLLRHTITGIAVLLLSAVLLIVGNTLRLNILNQRSEIEVLKLVGATDAFIHRPFLYTGIWFGVIGGMLAWWLTEVMVIWSEGVVKELAGLYNSNFRLVGMGAFDGFNLILLGALLGLIASWFSVHRHIRDIEPS
>NZ_CP007567.1|WP_005323433.1|4775168_4775840_-|cell-division-ATP-binding-protein-FtsE
MIRFDKVSKVYSGGHQALQKVSFHLRKGEMAFLTGHSGAGKSTLLKLISVMERPTDGRVFFHGDDVSHIQRSQIPYVRRQIGMIFQDHRLLMDRTVFDNVALPLVIDGYSHADINKRVAAALDKVGLLGKERYQPRMLSGGEQQRVGIARAIVNKPPLLLADEPTGNLDPQLSMDIMRLFEEFNRFGVSVLIATHDLGLIARMRYRTLTLKAGRMYSQEQEES

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	KY290953	Aeromonas phage 51, complete genome	26938-26969	0	1.0
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	MK804891	Aeromonas phage 2_D05, complete genome	28392-28423	0	1.0
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	MK804892	Aeromonas phage 4_D05, complete genome	27260-27291	0	1.0
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	NC_019527	Aeromonas phage vB_AsaM-56, complete genome	26938-26969	0	1.0
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	KY290954	Aeromonas phage 56, complete genome	26938-26969	0	1.0
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	KY290953	Aeromonas phage 51, complete genome	26937-26968	0	1.0
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	MK804891	Aeromonas phage 2_D05, complete genome	28391-28422	0	1.0
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	MK804892	Aeromonas phage 4_D05, complete genome	27259-27290	0	1.0
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	NC_019527	Aeromonas phage vB_AsaM-56, complete genome	26937-26968	0	1.0
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	KY290954	Aeromonas phage 56, complete genome	26937-26968	0	1.0
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	MH179474	Aeromonas phage 62AhydR11PP, complete genome	20024-20055	1	0.969
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	MH179474	Aeromonas phage 62AhydR11PP, complete genome	20025-20056	1	0.969
NZ_CP007567_9	9.1\|3337703\|27\|NZ_CP007567\|CRISPRCasFinder	3337703-3337729	27	NC_019362	Sulfitobacter guttiformis plasmid pSG53, complete sequence	27233-27259	2	0.926
NZ_CP007567_12	12.6\|4728871\|36\|NZ_CP007567\|CRISPRCasFinder	4728871-4728906	36	KY290953	Aeromonas phage 51, complete genome	26934-26969	2	0.944
NZ_CP007567_12	12.6\|4728871\|36\|NZ_CP007567\|CRISPRCasFinder	4728871-4728906	36	MK804891	Aeromonas phage 2_D05, complete genome	28388-28423	2	0.944
NZ_CP007567_12	12.6\|4728871\|36\|NZ_CP007567\|CRISPRCasFinder	4728871-4728906	36	MK804892	Aeromonas phage 4_D05, complete genome	27256-27291	2	0.944
NZ_CP007567_12	12.6\|4728871\|36\|NZ_CP007567\|CRISPRCasFinder	4728871-4728906	36	NC_019527	Aeromonas phage vB_AsaM-56, complete genome	26934-26969	2	0.944
NZ_CP007567_12	12.6\|4728871\|36\|NZ_CP007567\|CRISPRCasFinder	4728871-4728906	36	KY290954	Aeromonas phage 56, complete genome	26934-26969	2	0.944
NZ_CP007567_12	12.6\|4728871\|36\|NZ_CP007567\|CRISPRCasFinder	4728871-4728906	36	MH179474	Aeromonas phage 62AhydR11PP, complete genome	20024-20059	3	0.917
NZ_CP007567_12	12.1\|4728749\|32\|NZ_CP007567\|CRT	4728749-4728780	32	NZ_CP024314	Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence	1057197-1057228	6	0.812
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	NC_007950	Polaromonas sp. JS666 plasmid 2, complete sequence	5898-5929	6	0.812
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	NZ_CP049813	Monaibacterium sp. ALG8 plasmid unnamed2, complete sequence	2216-2247	7	0.781
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	NZ_CP049813	Monaibacterium sp. ALG8 plasmid unnamed2, complete sequence	2217-2248	8	0.75
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	NC_007950	Polaromonas sp. JS666 plasmid 2, complete sequence	5899-5930	8	0.75
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	NZ_CP015231	Epibacterium mobile F1926 plasmid unnamed1, complete sequence	343020-343051	8	0.75
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	369678-369709	9	0.719
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	NC_047977	Microbacterium phage Hendrix, complete genome	41444-41475	9	0.719
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	369679-369710	9	0.719
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	NC_047977	Microbacterium phage Hendrix, complete genome	41443-41474	9	0.719
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	NZ_CP054622	Azospirillum oryzae strain KACC 14407 plasmid unnamed7, complete sequence	301444-301475	10	0.688
NZ_CP007567_12	12.8\|4728872\|32\|NZ_CP007567\|PILER-CR	4728872-4728903	32	NZ_CP039651	Azospirillum sp. TSA2s plasmid p1	344187-344218	10	0.688
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	NZ_CP054622	Azospirillum oryzae strain KACC 14407 plasmid unnamed7, complete sequence	301445-301476	11	0.656
NZ_CP007567_12	12.3\|4728871\|32\|NZ_CP007567\|CRT	4728871-4728902	32	NZ_CP039651	Azospirillum sp. TSA2s plasmid p1	344188-344219	11	0.656

1. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to KY290953 (Aeromonas phage 51, complete genome) position: , mismatch: 0, identity: 1.0

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggtt	Protospacer
********************************

2. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to MK804891 (Aeromonas phage 2_D05, complete genome) position: , mismatch: 0, identity: 1.0

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggtt	Protospacer
********************************

3. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to MK804892 (Aeromonas phage 4_D05, complete genome) position: , mismatch: 0, identity: 1.0

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggtt	Protospacer
********************************

4. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to NC_019527 (Aeromonas phage vB_AsaM-56, complete genome) position: , mismatch: 0, identity: 1.0

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggtt	Protospacer
********************************

5. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to KY290954 (Aeromonas phage 56, complete genome) position: , mismatch: 0, identity: 1.0

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggtt	Protospacer
********************************

6. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to KY290953 (Aeromonas phage 51, complete genome) position: , mismatch: 0, identity: 1.0

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
gaaatcggtctcgatgaaaccggcgatggttg	Protospacer
********************************

7. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to MK804891 (Aeromonas phage 2_D05, complete genome) position: , mismatch: 0, identity: 1.0

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
gaaatcggtctcgatgaaaccggcgatggttg	Protospacer
********************************

8. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to MK804892 (Aeromonas phage 4_D05, complete genome) position: , mismatch: 0, identity: 1.0

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
gaaatcggtctcgatgaaaccggcgatggttg	Protospacer
********************************

9. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to NC_019527 (Aeromonas phage vB_AsaM-56, complete genome) position: , mismatch: 0, identity: 1.0

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
gaaatcggtctcgatgaaaccggcgatggttg	Protospacer
********************************

10. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to KY290954 (Aeromonas phage 56, complete genome) position: , mismatch: 0, identity: 1.0

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
gaaatcggtctcgatgaaaccggcgatggttg	Protospacer
********************************

11. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to MH179474 (Aeromonas phage 62AhydR11PP, complete genome) position: , mismatch: 1, identity: 0.969

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggtc	Protospacer
*******************************.

12. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to MH179474 (Aeromonas phage 62AhydR11PP, complete genome) position: , mismatch: 1, identity: 0.969

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
gaaatcggtctcgatgaaaccggcgatggtcg	Protospacer
******************************.*

13. spacer 9.1|3337703|27|NZ_CP007567|CRISPRCasFinder matches to NC_019362 (Sulfitobacter guttiformis plasmid pSG53, complete sequence) position: , mismatch: 2, identity: 0.926

gctggtcctgaacgcccggagccggag	CRISPR spacer
gctggtccagaacggccggagccggag	Protospacer
******** ***** ************

14. spacer 12.6|4728871|36|NZ_CP007567|CRISPRCasFinder matches to KY290953 (Aeromonas phage 51, complete genome) position: , mismatch: 2, identity: 0.944

cgaaatcggtctcgatgaaaccggcgatggttggtc	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggttgcgc	Protospacer
*********************************  *

15. spacer 12.6|4728871|36|NZ_CP007567|CRISPRCasFinder matches to MK804891 (Aeromonas phage 2_D05, complete genome) position: , mismatch: 2, identity: 0.944

cgaaatcggtctcgatgaaaccggcgatggttggtc	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggttgcgc	Protospacer
*********************************  *

16. spacer 12.6|4728871|36|NZ_CP007567|CRISPRCasFinder matches to MK804892 (Aeromonas phage 4_D05, complete genome) position: , mismatch: 2, identity: 0.944

cgaaatcggtctcgatgaaaccggcgatggttggtc	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggttgcgc	Protospacer
*********************************  *

17. spacer 12.6|4728871|36|NZ_CP007567|CRISPRCasFinder matches to NC_019527 (Aeromonas phage vB_AsaM-56, complete genome) position: , mismatch: 2, identity: 0.944

cgaaatcggtctcgatgaaaccggcgatggttggtc	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggttgcgc	Protospacer
*********************************  *

18. spacer 12.6|4728871|36|NZ_CP007567|CRISPRCasFinder matches to KY290954 (Aeromonas phage 56, complete genome) position: , mismatch: 2, identity: 0.944

cgaaatcggtctcgatgaaaccggcgatggttggtc	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggttgcgc	Protospacer
*********************************  *

19. spacer 12.6|4728871|36|NZ_CP007567|CRISPRCasFinder matches to MH179474 (Aeromonas phage 62AhydR11PP, complete genome) position: , mismatch: 3, identity: 0.917

cgaaatcggtctcgatgaaaccggcgatggttggtc	CRISPR spacer
cgaaatcggtctcgatgaaaccggcgatggtcgcac	Protospacer
*******************************.*  *

20. spacer 12.1|4728749|32|NZ_CP007567|CRT matches to NZ_CP024314 (Rhizobium sp. NXC24 plasmid pRspNXC24c, complete sequence) position: , mismatch: 6, identity: 0.812

cgacattgccgccagagagtgccgtgagtgcg---	CRISPR spacer
cgatattgccgccagagagggccg---gttcgaaa	Protospacer
***.*************** ****   ** **

21. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to NC_007950 (Polaromonas sp. JS666 plasmid 2, complete sequence) position: , mismatch: 6, identity: 0.812

cgaaatc--ggtctcgatgaaaccggcgatggtt	CRISPR spacer
--aggtcagggtctcggtgaaatcggcgatggtt	Protospacer
  *..**  *******.*****.***********

22. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to NZ_CP049813 (Monaibacterium sp. ALG8 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

gaaatcggtctcgatgaaaccg-----gcgatggttg	CRISPR spacer
gaaatcggtctcgaagaaatcggccccgcgat-----	Protospacer
************** ****.**     *****

23. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to NZ_CP049813 (Monaibacterium sp. ALG8 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
cgaaatcggtctcgaagaaatcggccccgcga	Protospacer
*************** ****.****  .*

24. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to NC_007950 (Polaromonas sp. JS666 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.75

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
ggtcagggtctcggtgaaatcggcgatggttt	Protospacer
*.    *******.*****.***********

25. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to NZ_CP015231 (Epibacterium mobile F1926 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
gtcaccatgctcgatgaaacccgcgatggctg	Protospacer
*  *.*.  ************ *******.**

26. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
tgccttcggcctcgatgaagccggcgatgacg	Protospacer
.*   ****.*********.*********..

27. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to NC_047977 (Microbacterium phage Hendrix, complete genome) position: , mismatch: 9, identity: 0.719

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
cggcggcgttctcgatgagaccggcgatgtcc	Protospacer
**. . ** *********.********** ..

28. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
gccttcggcctcgatgaagccggcgatgacgt	Protospacer
*   ****.*********.*********..

29. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to NC_047977 (Microbacterium phage Hendrix, complete genome) position: , mismatch: 9, identity: 0.719

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
ggcggcgttctcgatgagaccggcgatgtccg	Protospacer
*. . ** *********.********** ..*

30. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to NZ_CP054622 (Azospirillum oryzae strain KACC 14407 plasmid unnamed7, complete sequence) position: , mismatch: 10, identity: 0.688

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
ccgggcggtctcgatgaagcgggcgatgtcgg	Protospacer
  .. *************.* ******* . *

31. spacer 12.8|4728872|32|NZ_CP007567|PILER-CR matches to NZ_CP039651 (Azospirillum sp. TSA2s plasmid p1) position: , mismatch: 10, identity: 0.688

gaaatcggtctcgatgaaaccggcgatggttg	CRISPR spacer
ccgggcggtctcgatgaagcgggcgatgtcgg	Protospacer
  .. *************.* ******* . *

32. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to NZ_CP054622 (Azospirillum oryzae strain KACC 14407 plasmid unnamed7, complete sequence) position: , mismatch: 11, identity: 0.656

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
gccgggcggtctcgatgaagcgggcgatgtcg	Protospacer
   .. *************.* ******* .

33. spacer 12.3|4728871|32|NZ_CP007567|CRT matches to NZ_CP039651 (Azospirillum sp. TSA2s plasmid p1) position: , mismatch: 11, identity: 0.656

cgaaatcggtctcgatgaaaccggcgatggtt	CRISPR spacer
gccgggcggtctcgatgaagcgggcgatgtcg	Protospacer
   .. *************.* ******* .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

18718 : 57938

uncultured_Mediterranean_phage(14.29%)

transposase,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005331315.1\|18718_20062_+\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_005331316.1\|20142_21399_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_041204876.1\|21417_21675_-	BolA family iron metabolism protein IbaG	NA	NA	NA	NA
WP_005331319.1\|21674_21947_-	STAS domain-containing protein	NA	NA	NA	NA
WP_005331320.1\|21943_22579_-	phospholipid-binding protein MlaC	NA	NA	NA	NA
WP_005331321.1\|22581_23082_-	outer membrane lipid asymmetry maintenance protein MlaD	NA	NA	NA	NA
WP_041204877.1\|23089_23869_-	lipid asymmetry maintenance ABC transporter permease subunit MlaE	NA	NA	NA	NA
WP_005331323.1\|23868_24669_-	phospholipid ABC transporter ATP-binding protein MlaF	G3M9Y6	Bacillus_virus	2.5e-20	31.7
WP_041204878.1\|24875_25871_+	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	6.5e-42	37.9
WP_005331333.1\|25870_26425_+	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	1.7e-39	61.2
WP_005331338.1\|26421_26982_+	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_041204879.1\|26968_27487_+	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_010675872.1\|27499_28225_+	LPS export ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.0e-21	29.9
WP_041204880.1\|28290_29730_+	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_005305957.1\|29750_30038_+	ribosome hibernation promoting factor	NA	NA	NA	NA
WP_005331355.1\|30040_30487_+	PTS IIA-like nitrogen regulatory protein PtsN	NA	NA	NA	NA
WP_041204881.1\|30527_31394_+	RNase adapter RapZ	A0A1P8D5W0	Corynebacterium_phage	1.1e-10	33.3
WP_005331359.1\|31414_31687_+	PTS phosphocarrier protein NPr	NA	NA	NA	NA
WP_041204883.1\|32855_33977_-	outer membrane-stress sensor serine endopeptidase DegS	A0A1B1IT49	uncultured_Mediterranean_phage	1.8e-19	24.9
WP_041204884.1\|34066_35428_-	Do family serine endopeptidase	A0A1B1IT49	uncultured_Mediterranean_phage	1.4e-23	29.5
WP_005331369.1\|35509_35890_-	YhcB family protein	NA	NA	NA	NA
WP_041204885.1\|36029_37124_+	cell division protein ZapE	NA	NA	NA	NA
WP_005336289.1\|37390_37819_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_005331372.1\|37833_38226_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_025328515.1\|38526_39117_+	ubiquinol-cytochrome c reductase iron-sulfur subunit	NA	NA	NA	NA
WP_005331374.1\|39119_40337_+	cytochrome bc complex cytochrome b subunit	NA	NA	NA	NA
WP_041204887.1\|40333_41068_+	cytochrome c1	NA	NA	NA	NA
WP_025328513.1\|41155_41785_+	stringent starvation protein A	NA	NA	NA	NA
WP_025328512.1\|41802_42210_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.7e-28	48.5
WP_005331387.1\|42256_42835_-	divisome-associated lipoprotein YraP	NA	NA	NA	NA
WP_005331389.1\|42839_43430_-	SIS domain-containing protein	A0A067XQR2	Caulobacter_phage	7.3e-09	29.1
WP_081805612.1\|43439_43835_-	YraN family protein	NA	NA	NA	NA
WP_081805613.1\|43752_45663_-	penicillin-binding protein activator	NA	NA	NA	NA
WP_041204888.1\|45742_46576_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.6e-49	42.8
WP_041204889.1\|47196_48777_+	DUF3258 domain-containing protein	NA	NA	NA	NA
WP_012564931.1\|48780_49728_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_049832137.1\|49956_51042_+	sel1 repeat family protein	NA	NA	NA	NA
WP_019706001.1\|51396_52344_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_041204891.1\|53037_54174_-\|transposase	ISAs1-like element ISAeme1 family transposase	NA	NA	NA	NA
WP_148304680.1\|54594_55449_-	hypothetical protein	A0A0N9SHY1	Staphylococcus_phage	5.6e-18	36.1
WP_005329258.1\|55660_56290_-	recombinase family protein	M9Q1K0	Clostridium_phage	3.5e-09	31.0
WP_041204896.1\|56906_57938_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

87385 : 147008

Rhizobium_phage(12.5%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041204891.1\|87385_88522_-\|transposase	ISAs1-like element ISAeme1 family transposase	NA	NA	NA	NA
WP_005329217.1\|88966_89830_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_041204907.1\|89833_90304_-\|protease	TIGR02281 family clan AA aspartic protease	NA	NA	NA	NA
WP_041206797.1\|90440_91013_+	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	A0A076YN96	Rhizobium_phage	2.2e-10	32.6
WP_005329211.1\|91289_92054_+	pyruvate dehydrogenase complex transcriptional repressor PdhR	NA	NA	NA	NA
WP_005329209.1\|92122_94783_+	pyruvate dehydrogenase (acetyl-transferring), homodimeric type	NA	NA	NA	NA
WP_041204909.1\|94948_96835_+	pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase	NA	NA	NA	NA
WP_025328438.1\|96988_98416_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.3e-43	27.8
WP_005329200.1\|98544_99501_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	8.5e-15	34.8
WP_005329198.1\|99497_99812_-	hypothetical protein	NA	NA	NA	NA
WP_005329196.1\|100231_100444_-	hypothetical protein	NA	NA	NA	NA
WP_005329194.1\|100589_102500_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	4.3e-18	32.8
WP_041204910.1\|102779_105077_+	patatin-like phospholipase domain-containing protein	A0A1V0SFX9	Hokovirus	7.8e-06	27.5
WP_041206798.1\|105305_107903_+	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	NA	NA	NA	NA
WP_005329188.1\|108146_109721_+	cyclic diguanylate phosphodiesterase	NA	NA	NA	NA
WP_041204911.1\|109727_110639_-	LysR family transcriptional regulator	Q6JIH3	Burkholderia_virus	7.6e-13	25.9
WP_005329170.1\|110715_111333_+	LysE family transporter	NA	NA	NA	NA
WP_005329169.1\|111450_112857_+	FAD-binding protein	NA	NA	NA	NA
WP_041204913.1\|112928_114056_+	GTP-binding protein	NA	NA	NA	NA
WP_041204915.1\|114130_115528_+	multidrug transporter subunit MdtD	NA	NA	NA	NA
WP_041206799.1\|115544_116030_-	YbaK/EbsC family protein	NA	NA	NA	NA
WP_005329164.1\|116135_116645_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_005329162.1\|116644_117016_-	dihydroneopterin aldolase	NA	NA	NA	NA
WP_041204917.1\|117187_117850_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_041204919.1\|118553_119573_+	OmpA family protein	NA	NA	NA	NA
WP_011191341.1\|121476_122751_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_025328417.1\|122852_123452_+	YIP1 family protein	NA	NA	NA	NA
WP_041204923.1\|124407_125550_+\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_041204925.1\|125586_127038_+	histidine acid phosphatase	A0A218MNG5	uncultured_virus	3.4e-31	32.0
WP_049832139.1\|127100_127967_-	EamA family transporter	NA	NA	NA	NA
WP_005330581.1\|128073_128490_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_041204928.1\|128501_129629_-\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_081805618.1\|129951_130563_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_041204932.1\|130562_132227_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_005323487.1\|132309_133740_-	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_005323489.1\|133927_134875_-	HTH-type transcriptional regulator TreR	C6ZCU4	Enterobacteria_phage	8.1e-18	26.8
WP_005323502.1\|135012_135963_+	AEC family transporter	NA	NA	NA	NA
WP_041204934.1\|135967_137263_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_041204936.1\|137526_137832_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_005323508.1\|137871_139197_+	PTS cellobiose transporter subunit IIC	NA	NA	NA	NA
WP_005323509.1\|139250_140636_+	glycoside hydrolase family 1 protein	NA	NA	NA	NA
WP_005323512.1\|140709_141021_+	PTS N,N'-diacetylchitobiose transporter subunit IIA	NA	NA	NA	NA
WP_005323514.1\|141032_141962_+	ROK family protein	NA	NA	NA	NA
WP_005323515.1\|142186_143326_+	carbohydrate porin	NA	NA	NA	NA
WP_041204938.1\|143458_144421_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_041204941.1\|144483_144678_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_005323518.1\|144807_145848_+	L-asparaginase 2	NA	NA	NA	NA
WP_010676219.1\|145910_147008_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

310457 : 320692

Lactobacillus_phage(14.29%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205045.1\|310457_311522_+	LysM peptidoglycan-binding domain-containing protein	A0A0A7NU10	Lactobacillus_phage	4.9e-11	36.2
WP_099993964.1\|311681_312698_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_005331913.1\|313798_314782_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	4.9e-34	33.7
WP_005331910.1\|314869_315883_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	3.1e-108	58.6
WP_005309452.1\|316062_316278_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_005331908.1\|316293_316737_+	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	2.0e-27	48.6
WP_005331907.1\|316825_318613_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.0e-74	41.4
WP_081805626.1\|318826_320692_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-34	32.6

DBSCAN-SWA_4

366752 : 421969

Bacillus_phage(25.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041206812.1\|366752_367655_-\|tRNA	tRNA glutamyl-Q(34) synthetase GluQRS	NA	NA	NA	NA
WP_005329052.1\|367767_368217_-	RNA polymerase-binding protein DksA	NA	NA	NA	NA
WP_004576012.1\|368270_369689_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_005327571.1\|369880_370618_-	DNA/RNA nuclease SfsA	NA	NA	NA	NA
WP_005327573.1\|370614_371160_-	RNA 2',3'-cyclic phosphodiesterase	NA	NA	NA	NA
WP_041205066.1\|371396_373844_+	ATP-dependent helicase HrpB	M1PGM1	Moumouvirus	1.9e-26	28.4
WP_005327576.1\|374108_376430_+	penicillin-binding protein 1B	NA	NA	NA	NA
WP_005327577.1\|376472_376883_+	VOC family protein	NA	NA	NA	NA
WP_005327579.1\|376953_377274_-	multidrug transporter	NA	NA	NA	NA
WP_041205067.1\|377261_377654_-	multidrug transporter	NA	NA	NA	NA
WP_041205069.1\|377812_378694_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_041205070.1\|378748_379264_-	DUF2937 family protein	NA	NA	NA	NA
WP_005327588.1\|379473_380190_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_005327590.1\|380436_381342_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_162472483.1\|381397_381535_+	hypothetical protein	NA	NA	NA	NA
WP_005327593.1\|381573_382398_-	hypothetical protein	NA	NA	NA	NA
WP_005327596.1\|382608_383895_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_041205071.1\|384117_385512_+	H(+)/Cl(-) exchange transporter ClcA	NA	NA	NA	NA
WP_041205072.1\|385599_386292_+	hypothetical protein	NA	NA	NA	NA
WP_025328177.1\|386381_386732_+	iron-sulfur cluster insertion protein ErpA	A0A2H4N7M3	Lake_Baikal_phage	6.7e-26	49.5
WP_010674210.1\|392799_394413_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
WP_005327991.1\|394545_395178_+	LysE family translocator	NA	NA	NA	NA
WP_005309538.1\|395266_395563_-	DNA-binding transcriptional regulator Fis	NA	NA	NA	NA
WP_041205073.1\|395588_396554_-\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_005327981.1\|396894_398253_+	TolC family protein	NA	NA	NA	NA
WP_041206813.1\|398353_399331_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_005327974.1\|399330_400467_+	ABC transporter permease	NA	NA	NA	NA
WP_005327972.1\|400463_401669_+	ABC transporter permease	NA	NA	NA	NA
WP_005327970.1\|401747_402383_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_041205075.1\|402509_403364_-	ATP-binding protein	A0A1B1P8D0	Bacillus_phage	6.2e-09	28.4
WP_041206814.1\|403430_404105_-	hypothetical protein	NA	NA	NA	NA
WP_005327964.1\|404418_405390_+	response regulator	NA	NA	NA	NA
WP_041205076.1\|405462_406860_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	1.4e-79	38.8
WP_041205077.1\|407073_407985_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	2.0e-61	45.9
WP_005327958.1\|408079_408400_-	ComEA family DNA-binding protein	NA	NA	NA	NA
WP_005327957.1\|408565_409321_+	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_005327955.1\|409412_409709_-	YciI family protein	NA	NA	NA	NA
WP_005327953.1\|409732_410284_-	septation protein A	NA	NA	NA	NA
WP_005327951.1\|410418_411951_-	aminotransferase class V-fold PLP-dependent enzyme	NA	NA	NA	NA
WP_041205078.1\|412182_412818_+	hemolysin III family protein	NA	NA	NA	NA
WP_005327944.1\|412936_414598_+	putative transporter	NA	NA	NA	NA
WP_004576012.1\|416347_417766_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_012564931.1\|418007_418955_+\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_099993964.1\|419175_420192_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_049832144.1\|420263_420710_+	hypothetical protein	A0A0U1W0F5	Pseudomonas_phage	1.0e-31	42.2
WP_041204891.1\|420832_421969_+\|transposase	ISAs1-like element ISAeme1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

434641 : 493883

Tupanvirus(28.57%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041204928.1\|434641_435769_-\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_041205087.1\|436576_437770_+	multidrug efflux MFS transporter MdtH	NA	NA	NA	NA
WP_148304728.1\|437972_444458_-	VCBS domain-containing protein	NA	NA	NA	NA
WP_004576012.1\|444349_445768_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_041205088.1\|446490_446853_-	DUF2061 domain-containing protein	NA	NA	NA	NA
WP_005325909.1\|447034_447241_+	hypothetical protein	NA	NA	NA	NA
WP_005325910.1\|447322_448177_-	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_005325916.1\|448170_448632_-	DUF2390 domain-containing protein	NA	NA	NA	NA
WP_005325918.1\|448624_450535_-	ABC transporter ATP-binding protein	A0A2K9L0W2	Tupanvirus	2.1e-73	32.8
WP_005325920.1\|450687_451098_+	CBS domain-containing protein	NA	NA	NA	NA
WP_041204896.1\|451446_452478_+\|transposase	IS630-like element ISAhy2 family transposase	NA	NA	NA	NA
WP_099993964.1\|452647_453664_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_041205091.1\|453775_454843_+	porin	Q1MVN1	Enterobacteria_phage	6.3e-43	33.7
WP_041204923.1\|455338_456481_+\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_041205093.1\|457508_458117_-	arylesterase	NA	NA	NA	NA
WP_005325231.1\|458174_458885_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-32	37.9
WP_005325230.1\|458881_461323_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_005325229.1\|461387_462293_-	TIGR01777 family protein	NA	NA	NA	NA
WP_041205096.1\|462554_464105_+	EAL domain-containing protein	NA	NA	NA	NA
WP_005325227.1\|464232_465414_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_005325226.1\|465615_466683_-	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_041205099.1\|466960_467674_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_005325222.1\|467717_468050_+	YggL family protein	NA	NA	NA	NA
WP_005325214.1\|468149_469070_+	glutaminase B	NA	NA	NA	NA
WP_041205101.1\|469099_470392_+	sulfurtransferase	NA	NA	NA	NA
WP_041205103.1\|470594_470804_+	YgdI/YgdR family lipoprotein	NA	NA	NA	NA
WP_005325210.1\|470847_474411_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.0e-16	36.8
WP_005325209.1\|474510_475788_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_080675078.1\|476260_476482_+	hypothetical protein	NA	NA	NA	NA
WP_099993964.1\|477584_478601_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_041205105.1\|478767_479862_-	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_005326773.1\|480166_481207_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_081805630.1\|481356_481692_-	SemiSWEET transporter	NA	NA	NA	NA
WP_041205107.1\|481788_482760_-	galactose mutarotase	NA	NA	NA	NA
WP_041205109.1\|482756_483908_-	galactokinase	NA	NA	NA	NA
WP_041205111.1\|483904_484951_-	UDP-glucose--hexose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_041205112.1\|485002_486016_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	1.0e-82	46.8
WP_041205116.1\|486897_489174_-	immune inhibitor A	NA	NA	NA	NA
WP_041206820.1\|489606_489942_+	ribonuclease E inhibitor RraB	NA	NA	NA	NA
WP_041205051.1\|490033_491371_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_004576012.1\|492464_493883_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

818240 : 884107

Salmonella_phage(16.67%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005330603.1\|818240_819440_+\|tRNA	tyrosine--tRNA ligase	NA	NA	NA	NA
WP_041205253.1\|819488_820826_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005331295.1\|820954_823435_-	alpha-glucosidase	NA	NA	NA	NA
WP_005331291.1\|824019_825276_-	adenylosuccinate synthetase	A0A2R8FF47	Brazilian_cedratvirus	1.9e-46	31.1
WP_005331284.1\|825445_826354_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_041205255.1\|826647_828027_-	TAXI family TRAP transporter solute-binding subunit	NA	NA	NA	NA
WP_005331282.1\|828221_829364_-	PatB family C-S lyase	NA	NA	NA	NA
WP_005331280.1\|829527_830700_+	MFS transporter	NA	NA	NA	NA
WP_005331279.1\|830769_831654_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005331278.1\|831741_832497_-	YciK family oxidoreductase	NA	NA	NA	NA
WP_041205257.1\|832718_833726_+\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	7.8e-19	29.4
WP_005331270.1\|833969_835307_-	N-succinylarginine dihydrolase	NA	NA	NA	NA
WP_041205259.1\|835667_838289_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	6.0e-87	34.3
WP_162852227.1\|838404_838575_+	hypothetical protein	NA	NA	NA	NA
WP_041205261.1\|838595_838952_-	MGMT family protein	NA	NA	NA	NA
WP_005331260.1\|839029_840583_-	methyl-accepting chemotaxis protein	A0A1B0V854	Salmonella_phage	5.4e-35	43.9
WP_005331253.1\|840783_842649_-	family 20 glycosylhydrolase	NA	NA	NA	NA
WP_041205271.1\|842844_843717_-	N-acetylglucosamine kinase	NA	NA	NA	NA
WP_041205273.1\|843709_845425_-	glycoside hydrolase family 9 protein	NA	NA	NA	NA
WP_041205274.1\|845527_846520_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.2e-17	33.2
WP_005331243.1\|846531_847554_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	8.5e-13	27.2
WP_005331241.1\|847550_848465_-	ABC transporter permease	NA	NA	NA	NA
WP_005331240.1\|848466_849450_-	ABC transporter permease	NA	NA	NA	NA
WP_041205282.1\|849567_851250_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005331236.1\|852234_852444_+	hypothetical protein	NA	NA	NA	NA
WP_041205288.1\|852589_853057_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_041206848.1\|853219_854545_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_081805644.1\|855083_856181_-\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_011191341.1\|856461_857736_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_041205297.1\|859581_860856_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_011191341.1\|861754_863029_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_012564931.1\|864201_865149_+\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_005327117.1\|866093_867107_-\|transposase	IS21-like element ISAeme17 family transposase	A0A2L1IVA1	Escherichia_phage	6.5e-74	45.8
WP_001162010.1\|867721_868279_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	3.4e-48	81.3
WP_005327104.1\|868409_869897_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_003056106.1\|869883_870357_-	cytochrome c	NA	NA	NA	NA
WP_041205303.1\|870385_871096_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-31	38.3
WP_004393995.1\|871097_872303_-	ABC transporter permease	NA	NA	NA	NA
WP_023266980.1\|872299_873451_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004393990.1\|873447_874056_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_019706001.1\|876174_877122_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_005323562.1\|878811_879729_-\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-101	59.5
WP_041205297.1\|881775_883050_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_081805647.1\|883159_884107_+\|transposase	IS481-like element ISAeme21 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

900314 : 971396

Bacillus_thuringiensis_phage(12.5%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205051.1\|900314_901652_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005331469.1\|901696_902281_-	superoxide dismutase [Fe]	Q56AR7	Bacillus_thuringiensis_phage	2.5e-41	43.6
WP_005331467.1\|902569_902914_+	Grx4 family monothiol glutaredoxin	NA	NA	NA	NA
WP_041205332.1\|902979_904191_-	RsmB/NOP family class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_005331463.1\|904401_906387_+	hypothetical protein	NA	NA	NA	NA
WP_041205334.1\|906383_906707_+	hypothetical protein	NA	NA	NA	NA
WP_041205337.1\|906870_907509_+	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
WP_005331459.1\|907508_908420_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004576012.1\|908424_909843_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_005328858.1\|910242_910506_+	DUF2282 domain-containing protein	NA	NA	NA	NA
WP_005328857.1\|910567_911410_+	DUF692 domain-containing protein	NA	NA	NA	NA
WP_005328856.1\|911402_912155_+	DUF2063 domain-containing protein	NA	NA	NA	NA
WP_161507826.1\|912199_912607_+	DoxX family membrane protein	NA	NA	NA	NA
WP_041205339.1\|912694_913159_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005328853.1\|913351_914647_+	PAS domain S-box protein	A0A2H4J162	uncultured_Caudovirales_phage	3.7e-13	41.1
WP_005328852.1\|914808_915366_+	DUF3332 domain-containing protein	NA	NA	NA	NA
WP_041205341.1\|915453_916827_+	HD-GYP domain-containing protein	NA	NA	NA	NA
WP_005328849.1\|917064_917817_-	molybdopterin-guanine dinucleotide biosynthesis protein B	NA	NA	NA	NA
WP_005328848.1\|917813_918428_-	molybdenum cofactor guanylyltransferase	NA	NA	NA	NA
WP_005328846.1\|918697_920407_+	NAD-dependent malic enzyme	NA	NA	NA	NA
WP_041205344.1\|920788_922027_+	uracil-xanthine permease	NA	NA	NA	NA
WP_041205346.1\|922177_922918_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_005328842.1\|923168_923735_+	lipoprotein	NA	NA	NA	NA
WP_041205347.1\|923807_924818_-	beta-propeller fold lactonase family protein	NA	NA	NA	NA
WP_005328840.1\|924931_925690_-	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_041205348.1\|925939_926122_+	hypothetical protein	NA	NA	NA	NA
WP_021141311.1\|926871_928008_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_049832153.1\|929752_931198_+	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-17	30.3
WP_004576012.1\|931152_932571_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_005328697.1\|932792_933770_+	ABC transporter permease	NA	NA	NA	NA
WP_005328698.1\|933800_935408_+	glycosyl hydrolase family 3	NA	NA	NA	NA
WP_041205349.1\|935534_937706_+	sugar-binding protein	NA	NA	NA	NA
WP_005328700.1\|937802_938411_-	LysE family translocator	NA	NA	NA	NA
WP_005328701.1\|938534_941852_-	mechanosensitive channel MscK	NA	NA	NA	NA
WP_041205351.1\|942001_943414_-	pyruvate kinase PykF	NA	NA	NA	NA
WP_005328704.1\|943792_944923_-	cupin domain-containing protein	NA	NA	NA	NA
WP_005328706.1\|945079_946450_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	8.2e-112	47.3
WP_041205352.1\|946625_947237_-	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_005328710.1\|947260_948367_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_005328711.1\|948524_948992_-	NUDIX hydrolase	A0A023W5N2	Serratia_phage	8.6e-05	62.2
WP_041205353.1\|948988_949921_-	pseudouridine synthase	NA	NA	NA	NA
WP_005328714.1\|950056_950824_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_005328715.1\|950824_951130_-	PTS fructose transporter subunit IIB	NA	NA	NA	NA
WP_005328717.1\|951342_952749_-	hexose-6-phosphate:phosphate antiporter	NA	NA	NA	NA
WP_005328732.1\|953212_955117_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_081805649.1\|955614_955986_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_012564931.1\|956523_957471_+\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_041206859.1\|957791_958046_-	hypothetical protein	NA	NA	NA	NA
WP_041205354.1\|958250_958694_-	CopD family protein	NA	NA	NA	NA
WP_041205355.1\|959713_962038_+	Ig-like domain-containing protein	J9Q6D6	Salmonella_phage	5.1e-05	27.6
WP_005328918.1\|962235_964122_-	PTS fructose transporter subunit EIIC	NA	NA	NA	NA
WP_005328920.1\|964796_964946_+	hypothetical protein	NA	NA	NA	NA
WP_005328921.1\|965085_965634_-	YgjV family protein	NA	NA	NA	NA
WP_005328923.1\|965822_967022_-	mannose-6-phosphate isomerase, class I	NA	NA	NA	NA
WP_041205357.1\|967151_968027_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005328927.1\|968222_969476_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	1.6e-13	72.2
WP_005328937.1\|969570_969747_-	hypothetical protein	NA	NA	NA	NA
WP_041205358.1\|970067_971396_-\|transposase	IS4-like element ISAeme12 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

1013645 : 1037439

Helicobacter_phage(28.57%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081805654.1\|1013645_1014062_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-44	60.1
WP_041205370.1\|1014083_1015289_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	1.2e-135	61.1
WP_041205372.1\|1016483_1016846_-	copper-binding protein	NA	NA	NA	NA
WP_041205373.1\|1016892_1020015_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_005330267.1\|1020088_1021606_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_041205374.1\|1021855_1022362_-	hypothetical protein	NA	NA	NA	NA
WP_041205378.1\|1022560_1023367_-	exodeoxyribonuclease III	A0A0N9QXX6	Chrysochromulina_ericina_virus	5.7e-12	27.5
WP_041205379.1\|1023592_1024555_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_041205574.1\|1024666_1025092_-\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_041206863.1\|1025149_1026289_+\|transposase	transposase	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_005326910.1\|1026352_1027999_-	response regulator	NA	NA	NA	NA
WP_041205380.1\|1028276_1028702_+	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	3.9e-12	40.0
WP_005326908.1\|1028744_1029785_-	FAD:protein FMN transferase ApbE	NA	NA	NA	NA
WP_041205381.1\|1030086_1030527_+	azurin	NA	NA	NA	NA
WP_041205382.1\|1030718_1030922_+	hypothetical protein	NA	NA	NA	NA
WP_005326904.1\|1030935_1031496_-	HutD family protein	NA	NA	NA	NA
WP_005326903.1\|1031760_1032729_+	nucleoside hydrolase	NA	NA	NA	NA
WP_005326902.1\|1032831_1033161_+	DUF3634 family protein	NA	NA	NA	NA
WP_005326901.1\|1033264_1034173_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005326900.1\|1034293_1034737_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_019706001.1\|1035194_1036142_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_041205384.1\|1036341_1037439_+\|transposase	ISAs1-like element ISAeme2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

1044537 : 1105465

Staphylococcus_prophage(30.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205253.1\|1044537_1045875_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_041205389.1\|1045998_1047102_-	YdcF family protein	NA	NA	NA	NA
WP_005332127.1\|1047251_1048145_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_081805658.1\|1048245_1048734_+	DMT family transporter	NA	NA	NA	NA
WP_041205391.1\|1048744_1049173_+	DMT family transporter	NA	NA	NA	NA
WP_005332143.1\|1049451_1049694_-	DUF3297 family protein	NA	NA	NA	NA
WP_005332142.1\|1049792_1051109_-	HipA domain-containing protein	NA	NA	NA	NA
WP_049832154.1\|1051092_1051389_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_041204928.1\|1051918_1053046_-\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_019706001.1\|1053185_1054133_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_148304683.1\|1054738_1057411_-	glycosyltransferase	NA	NA	NA	NA
WP_005325277.1\|1057429_1058911_-	hypothetical protein	NA	NA	NA	NA
WP_005325275.1\|1059195_1060566_-	hypothetical protein	NA	NA	NA	NA
WP_041205393.1\|1061070_1062273_-	sugar transporter	NA	NA	NA	NA
WP_005325270.1\|1062288_1062939_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	2.0e-07	23.3
WP_041205394.1\|1062961_1063762_-	ABC transporter permease	NA	NA	NA	NA
WP_041205395.1\|1063825_1065601_-	polysaccharide export protein	NA	NA	NA	NA
WP_041205396.1\|1065625_1066000_-	hypothetical protein	NA	NA	NA	NA
WP_011191341.1\|1066547_1067822_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_005328138.1\|1068819_1069461_-	hypothetical protein	NA	NA	NA	NA
WP_005328140.1\|1069555_1070398_-	pyruvate formate lyase 1-activating protein	M4MAG2	Vibrio_phage	9.2e-05	37.5
WP_005328143.1\|1070473_1073413_-	GGDEF and EAL domain-containing protein	A0A127AWB9	Bacillus_phage	1.9e-09	28.7
WP_041205397.1\|1073547_1075236_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_148304684.1\|1075345_1076362_+\|transposase	IS5 family transposase	Q38213	Escherichia_phage	7.0e-185	98.2
WP_081805660.1\|1076461_1077382_+	MFS transporter	NA	NA	NA	NA
WP_041205398.1\|1077477_1077906_-	two pore domain potassium channel family protein	NA	NA	NA	NA
WP_041205399.1\|1077955_1079122_-\|transposase	transposase	A0A077SLN2	Escherichia_phage	7.4e-146	67.9
WP_041205400.1\|1079233_1080268_-	DUF2955 domain-containing protein	NA	NA	NA	NA
WP_005325891.1\|1080276_1081368_-	HlyD family secretion protein	NA	NA	NA	NA
WP_041205402.1\|1081360_1082878_-	TolC family protein	NA	NA	NA	NA
WP_041205404.1\|1084013_1084961_+\|transposase	IS30-like element ISAeca1 family transposase	W5R8L2	Staphylococcus_phage	6.0e-45	37.7
WP_081805859.1\|1085501_1090439_+	alpha-2-macroglobulin family protein	NA	NA	NA	NA
WP_041205406.1\|1090449_1092849_+	penicillin-binding protein 1C	NA	NA	NA	NA
WP_041206870.1\|1092921_1093881_-	hypothetical protein	NA	NA	NA	NA
WP_005326435.1\|1094056_1095505_+\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_005326432.1\|1095579_1095972_-	hypothetical protein	NA	NA	NA	NA
WP_025326511.1\|1096073_1096706_-	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_005326428.1\|1097122_1098010_+	flagellin	NA	NA	NA	NA
WP_005326427.1\|1098240_1098510_+	flagellar protein FlaG	NA	NA	NA	NA
WP_005326426.1\|1098538_1099918_+	flagellar filament capping protein FliD	NA	NA	NA	NA
WP_041204891.1\|1100364_1101501_-\|transposase	ISAs1-like element ISAeme1 family transposase	NA	NA	NA	NA
WP_041205407.1\|1101631_1101955_+	hypothetical protein	NA	NA	NA	NA
WP_099369027.1\|1101959_1102976_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.1
WP_041205409.1\|1103494_1104442_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.2e-40	35.7
WP_012564931.1\|1104517_1105465_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9

DBSCAN-SWA_10

1151480 : 1203626

Escherichia_phage(22.22%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011191341.1\|1151480_1152755_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_041205431.1\|1152948_1153395_+	isoprenylcysteine carboxylmethyltransferase family protein	NA	NA	NA	NA
WP_005330120.1\|1153451_1154711_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_049832155.1\|1154913_1155384_-	hypothetical protein	NA	NA	NA	NA
WP_005330115.1\|1155818_1157162_-	dihydroorotase	NA	NA	NA	NA
WP_041205433.1\|1157241_1158117_+	6-carboxytetrahydropterin synthase	A0A140B3P3	Vibrio_phage	1.4e-11	24.1
WP_005330109.1\|1160462_1160813_+	purine nucleoside phosphoramidase	NA	NA	NA	NA
WP_005330108.1\|1160812_1162234_+	hypothetical protein	NA	NA	NA	NA
WP_041205436.1\|1162300_1162699_+	YcfL family protein	NA	NA	NA	NA
WP_041205438.1\|1162698_1163295_+	penicillin-binding protein activator LpoB	NA	NA	NA	NA
WP_041205440.1\|1163284_1164148_+	phosphotransferase	NA	NA	NA	NA
WP_041205443.1\|1164201_1165062_+	hypothetical protein	NA	NA	NA	NA
WP_041205445.1\|1165130_1165628_+	hypothetical protein	NA	NA	NA	NA
WP_041205447.1\|1165815_1166982_+\|transposase	transposase	A0A077SLN2	Escherichia_phage	7.4e-146	67.9
WP_041205449.1\|1167188_1167593_-\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	1.1e-29	54.8
WP_021141234.1\|1167650_1168877_+\|transposase	transposase	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_041205451.1\|1168938_1170708_+	protein translocase subunit SecD	NA	NA	NA	NA
WP_171269622.1\|1170808_1171723_+	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.3e-33	33.7
WP_005331588.1\|1171802_1172405_-	DUF924 domain-containing protein	A0A1V0SIY0	Klosneuvirus	7.2e-20	35.3
WP_041205454.1\|1172615_1173533_+	DUF808 domain-containing protein	NA	NA	NA	NA
WP_005331593.1\|1175835_1177644_+	M3 family oligoendopeptidase	A0A1X9I5X5	Streptococcus_phage	1.6e-09	22.9
WP_005331594.1\|1177853_1178393_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_005331597.1\|1178467_1179760_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_005331601.1\|1181016_1181334_+	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_012564931.1\|1181883_1182831_+\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_005327567.1\|1183797_1186059_-	LTA synthase family protein	NA	NA	NA	NA
WP_041205459.1\|1186309_1187404_+	hypothetical protein	NA	NA	NA	NA
WP_005327565.1\|1187540_1188893_-	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
WP_148304685.1\|1188957_1189137_+	hypothetical protein	NA	NA	NA	NA
WP_041206877.1\|1189310_1190639_-	amino-acid N-acetyltransferase	NA	NA	NA	NA
WP_005327561.1\|1190891_1191524_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_041206878.1\|1191790_1192126_-	DUF3802 family protein	NA	NA	NA	NA
WP_005327557.1\|1192137_1192674_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005327555.1\|1192679_1193051_-	MmcQ/YjbR family DNA-binding protein	NA	NA	NA	NA
WP_041205463.1\|1193159_1193969_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_005327551.1\|1194007_1194913_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_041205465.1\|1195048_1196746_+	L-lactate permease	NA	NA	NA	NA
WP_081805666.1\|1196758_1197535_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_005327547.1\|1197527_1198964_+	iron-sulfur cluster-binding protein	NA	NA	NA	NA
WP_041205467.1\|1198965_1199610_+	LUD domain-containing protein	NA	NA	NA	NA
WP_041205469.1\|1199609_1202402_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_099369027.1\|1202609_1203626_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.1

DBSCAN-SWA_11

1227204 : 1271364

Staphylococcus_prophage(50.0%)

integrase,transposase

attL 1233490:1233513|attR 1271374:1271397

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010674210.1\|1227204_1228818_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
WP_049832156.1\|1229021_1229855_-	hypothetical protein	NA	NA	NA	NA
WP_049832157.1\|1229851_1231633_-	hypothetical protein	NA	NA	NA	NA
WP_041205484.1\|1231697_1232210_-	hypothetical protein	NA	NA	NA	NA
WP_012564931.1\|1232525_1233473_+\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
1233490:1233513	attL	NA	NA	NA	NA
WP_005327636.1\|1234748_1235975_-\|integrase	site-specific integrase	A0A221SAN4	Ralstonia_phage	2.4e-22	29.2
WP_005327660.1\|1236281_1236728_-	DUF2787 family protein	NA	NA	NA	NA
WP_005327662.1\|1236794_1237280_-	hypothetical protein	NA	NA	NA	NA
WP_005327664.1\|1237299_1237824_-	hypothetical protein	NA	NA	NA	NA
WP_019706001.1\|1238073_1239021_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_041205486.1\|1239465_1239828_-	hypothetical protein	NA	NA	NA	NA
WP_148304686.1\|1239824_1240067_-	hypothetical protein	NA	NA	NA	NA
WP_081805667.1\|1240292_1240532_-	hypothetical protein	NA	NA	NA	NA
WP_019706001.1\|1240785_1241733_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_041205490.1\|1242790_1244527_+	C4-dicarboxylic acid transporter DauA	A0A2H4J153	uncultured_Caudovirales_phage	1.0e-29	23.3
WP_148304730.1\|1245203_1246145_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_099369027.1\|1246205_1247222_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.1
WP_005330929.1\|1247484_1248084_+	recombination protein RecR	NA	NA	NA	NA
WP_005330931.1\|1248365_1250279_+	molecular chaperone HtpG	A0A1B1ISV4	uncultured_Mediterranean_phage	1.0e-115	36.2
WP_005330936.1\|1250532_1251177_+	adenylate kinase	NA	NA	NA	NA
WP_041205492.1\|1251291_1252266_+	ferrochelatase	NA	NA	NA	NA
WP_005325024.1\|1252330_1252723_+	MAPEG family protein	NA	NA	NA	NA
WP_158319058.1\|1252909_1253059_+	hypothetical protein	NA	NA	NA	NA
WP_103244595.1\|1253121_1254550_+\|transposase	IS66-like element ISAeme23 family transposase	NA	NA	NA	NA
WP_041205499.1\|1254565_1255522_+	ferrochelatase	NA	NA	NA	NA
WP_005325024.1\|1255586_1255979_+	MAPEG family protein	NA	NA	NA	NA
WP_041205502.1\|1256165_1257470_+	inosine/guanosine kinase	NA	NA	NA	NA
WP_010674427.1\|1259373_1259736_+	DUF2750 domain-containing protein	NA	NA	NA	NA
WP_041205505.1\|1259907_1260402_+	hypothetical protein	NA	NA	NA	NA
WP_041205507.1\|1260364_1262002_-	EAL domain-containing protein	NA	NA	NA	NA
WP_041205509.1\|1262189_1263464_+	glucose-1-phosphate adenylyltransferase	NA	NA	NA	NA
WP_041206884.1\|1263542_1265543_-	hypothetical protein	NA	NA	NA	NA
WP_005326480.1\|1265678_1266230_-	lipoprotein	NA	NA	NA	NA
WP_041205511.1\|1266552_1267740_+	isochorismate synthase	NA	NA	NA	NA
WP_005326477.1\|1267816_1269478_+	(2,3-dihydroxybenzoyl)adenylate synthase	NA	NA	NA	NA
WP_019706001.1\|1270416_1271364_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
1271374:1271397	attR	NA	NA	NA	NA

DBSCAN-SWA_12

1314251 : 1408338

Aeromonas_phage(15.79%)

portal,terminase,tail,transposase,protease,integrase

attL 1325382:1325397|attR 1410631:1410646

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049832160.1\|1314251_1315445_+\|integrase	site-specific integrase	K7P7J2	Enterobacteria_phage	1.8e-86	45.1
WP_005324058.1\|1315603_1316071_-	single-stranded DNA-binding protein	R9TR60	Vibrio_phage	2.2e-48	62.7
WP_005324055.1\|1316067_1316682_-	3'-5' exoribonuclease	A0A1U9ZA60	Proteus_phage	2.7e-14	27.1
WP_041205538.1\|1316703_1317003_-	hypothetical protein	NA	NA	NA	NA
WP_041205544.1\|1317016_1317433_-	hypothetical protein	NA	NA	NA	NA
WP_005324029.1\|1317519_1317711_-	hypothetical protein	NA	NA	NA	NA
WP_041205547.1\|1317707_1318166_-	hypothetical protein	NA	NA	NA	NA
WP_005324025.1\|1318155_1318323_-	hypothetical protein	NA	NA	NA	NA
WP_005324021.1\|1320166_1320511_-	DUF4406 domain-containing protein	A0A1I9KFD3	Aeromonas_phage	4.4e-22	59.1
WP_081805672.1\|1320645_1321230_-	hypothetical protein	NA	NA	NA	NA
WP_041205550.1\|1321434_1322085_-	helix-turn-helix domain-containing protein	A0A1I9KG86	Aeromonas_phage	1.7e-43	47.7
WP_049832161.1\|1322172_1322349_+	helix-turn-helix domain-containing protein	H9C161	Pectobacterium_phage	2.6e-07	51.0
WP_049832162.1\|1322345_1322867_+	phage regulatory CII family protein	NA	NA	NA	NA
WP_005324016.1\|1322944_1323157_+	hypothetical protein	NA	NA	NA	NA
WP_049832163.1\|1323149_1324070_+	replication protein	A0A0M5M7Y1	Salmonella_phage	8.4e-20	44.3
WP_005324011.1\|1324069_1324738_+	replication P family protein	A0A1I9KFB0	Aeromonas_phage	2.8e-81	69.1
WP_193354202.1\|1324724_1325093_+	hypothetical protein	NA	NA	NA	NA
WP_148304688.1\|1325098_1325374_+	hypothetical protein	NA	NA	NA	NA
1325382:1325397	attL	NA	NA	NA	NA
WP_102948395.1\|1325459_1326161_+	phage antirepressor KilAC domain-containing protein	A0A1I9KFA9	Aeromonas_phage	1.5e-61	57.3
WP_005324004.1\|1326157_1326355_+	DUF3283 family protein	NA	NA	NA	NA
WP_148304689.1\|1326351_1327344_+	DUF968 domain-containing protein	R9TRM9	Vibrio_phage	8.2e-29	34.9
WP_041205558.1\|1327330_1327717_+	RusA family crossover junction endodeoxyribonuclease	A0A1J0GV15	Halomonas_phage	1.5e-18	45.8
WP_148304731.1\|1327793_1328333_+	antitermination protein	NA	NA	NA	NA
WP_033132437.1\|1328526_1328733_+	hypothetical protein	NA	NA	NA	NA
WP_041205562.1\|1328735_1329227_+	lysozyme	A0A193GZ38	Enterobacter_phage	3.0e-16	39.3
WP_042047481.1\|1329226_1329766_+	DUF2514 domain-containing protein	A0A2D1GNE2	Pseudomonas_phage	2.6e-05	49.3
WP_081805673.1\|1329949_1330429_+\|terminase	terminase small subunit	O64316	Escherichia_phage	6.9e-42	56.1
WP_049832229.1\|1330499_1332347_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	2.7e-190	56.9
WP_005323973.1\|1332343_1332553_+	hypothetical protein	NA	NA	NA	NA
WP_041205568.1\|1332549_1334112_+\|portal	phage portal protein	A0A0A0YUB7	Pseudomonas_phage	7.6e-138	51.0
WP_005323970.1\|1334065_1336129_+\|protease	Clp protease ClpP	A0A1W6JT88	Pseudomonas_phage	5.8e-194	53.4
WP_041205570.1\|1336186_1336501_+	DUF2190 family protein	A0A088C4T4	Shewanella_sp._phage	4.4e-05	49.1
WP_005323966.1\|1336500_1336797_+	hypothetical protein	NA	NA	NA	NA
WP_005323964.1\|1336804_1337413_+\|tail	phage tail protein	K7P7A8	Enterobacteria_phage	1.2e-19	37.6
WP_005323962.1\|1337447_1337615_+	hypothetical protein	NA	NA	NA	NA
WP_041205572.1\|1337647_1338049_+	hypothetical protein	NA	NA	NA	NA
WP_005323958.1\|1338048_1338525_+\|tail	putative major tail protein	M9NYX0	Enterobacteria_phage	2.4e-26	45.0
WP_005323956.1\|1338521_1338959_+	hypothetical protein	NA	NA	NA	NA
WP_148304690.1\|1338976_1339294_+	hypothetical protein	NA	NA	NA	NA
WP_049832164.1\|1339274_1341401_+	hypothetical protein	A0A2I7S778	Vibrio_phage	3.8e-31	32.1
WP_049832165.1\|1341397_1342000_+	hypothetical protein	A0A2I2L6V8	Escherichia_phage	2.5e-36	41.8
WP_005324799.1\|1341996_1342581_+	hypothetical protein	S4TND4	Salmonella_phage	5.3e-44	51.9
WP_005324797.1\|1342583_1342985_+	hypothetical protein	Q7Y3Z5	Yersinia_phage	1.5e-34	52.3
WP_049832166.1\|1342984_1348807_+	DUF1983 domain-containing protein	Q7Y3Z3	Yersinia_phage	1.2e-10	40.0
WP_005325293.1\|1348863_1350525_+	hypothetical protein	A0A1I9KFH7	Aeromonas_phage	6.2e-21	39.9
WP_005325297.1\|1350521_1350836_+	hypothetical protein	A0A2R4ALX6	Aeromonas_phage	1.2e-39	81.6
WP_041205574.1\|1350972_1351398_-\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_041206863.1\|1351456_1352596_+\|transposase	transposase	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_041205576.1\|1353038_1353752_-	metallophosphoesterase	A0A2H4J0P0	uncultured_Caudovirales_phage	3.1e-78	59.5
WP_041205242.1\|1353972_1355310_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005332463.1\|1355430_1357986_+	bifunctional lysylphosphatidylglycerol flippase/synthetase MprF	NA	NA	NA	NA
WP_041205579.1\|1357996_1358707_+	virulence factor	NA	NA	NA	NA
WP_005332471.1\|1359627_1360443_-	carbon-nitrogen hydrolase family protein	M1HZ02	Paramecium_bursaria_Chlorella_virus	4.4e-12	26.1
WP_005332473.1\|1360451_1361603_-	methionine aminotransferase	NA	NA	NA	NA
WP_005332475.1\|1361717_1362608_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005332477.1\|1362714_1364214_-	L-arabinose isomerase	NA	NA	NA	NA
WP_041205582.1\|1364227_1364926_-	L-ribulose-5-phosphate 4-epimerase	NA	NA	NA	NA
WP_005332481.1\|1364922_1366614_-	ribulokinase	NA	NA	NA	NA
WP_041205585.1\|1366975_1367959_+	arabinose ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005332486.1\|1368031_1369531_+	L-arabinose ABC transporter ATP-binding protein AraG	A0A2H4PQG7	Staphylococcus_phage	3.0e-14	27.0
WP_004576012.1\|1369763_1371182_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_041205587.1\|1371421_1372108_+	hypothetical protein	NA	NA	NA	NA
WP_005326786.1\|1372104_1372566_+	YjiG family protein	NA	NA	NA	NA
WP_041205590.1\|1372578_1373745_+	beta-aspartyl-peptidase	NA	NA	NA	NA
WP_005327996.1\|1374908_1376327_-\|transposase	IS66-like element ISUnCu16 family transposase	NA	NA	NA	NA
WP_041205593.1\|1377410_1378322_+	arabinose operon transcriptional regulator AraC	NA	NA	NA	NA
WP_005328277.1\|1378409_1378535_-	50S ribosomal protein L36	NA	NA	NA	NA
WP_005328284.1\|1378534_1378801_-	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_005328287.1\|1379056_1379311_+	DinI family protein	NA	NA	NA	NA
WP_042649063.1\|1379442_1380264_-	DUF2927 domain-containing protein	NA	NA	NA	NA
WP_005328302.1\|1380288_1380792_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_005328305.1\|1380922_1382566_-	hypothetical protein	NA	NA	NA	NA
WP_041205597.1\|1382827_1384489_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_005328325.1\|1384590_1385943_-	anaerobic C4-dicarboxylate transporter DcuC	NA	NA	NA	NA
WP_139751191.1\|1386313_1387624_+\|integrase	site-specific integrase	A0A2H4JB45	uncultured_Caudovirales_phage	2.6e-83	41.6
WP_019706001.1\|1387726_1388674_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_021141278.1\|1388991_1390554_+\|transposase	IS21-like element ISAs28 family transposase	K4I413	Acidithiobacillus_phage	9.6e-125	46.0
WP_021141277.1\|1390577_1391333_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.4e-52	45.4
WP_041204923.1\|1391535_1392678_-\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_041205601.1\|1393400_1394351_-\|transposase	IS1595-like element ISAeca5 family transposase	NA	NA	NA	NA
WP_041205297.1\|1394475_1395750_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_041205601.1\|1396455_1397406_-\|transposase	IS1595-like element ISAeca5 family transposase	NA	NA	NA	NA
WP_021141311.1\|1397914_1399051_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_019706001.1\|1399668_1400616_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_010676219.1\|1401650_1402748_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_021141311.1\|1404509_1405646_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_019706001.1\|1406077_1407025_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_041205603.1\|1407357_1408338_-\|integrase	site-specific integrase	NA	NA	NA	NA
1410631:1410646	attR	NA	NA	NA	NA

DBSCAN-SWA_13

1438142 : 1540272

Enterococcus_phage(14.29%)

integrase,transposase

attL 1468583:1468642|attR 1549854:1549870

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021141311.1\|1438142_1439279_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_005332462.1\|1439543_1439843_-	H-NS histone family protein	NA	NA	NA	NA
WP_041205613.1\|1440420_1442001_+	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_005332460.1\|1442087_1442669_+	thymidine kinase	A0A0F6TIQ8	Escherichia_coli_O157_typing_phage	1.4e-49	52.7
WP_005332459.1\|1442735_1444073_-	flavohemoglobin expression-modulating QEGLA motif protein	NA	NA	NA	NA
WP_161507131.1\|1444232_1444688_+	YbjN domain-containing protein	NA	NA	NA	NA
WP_005330598.1\|1445049_1446834_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_041205614.1\|1446830_1447736_+	hypothetical protein	NA	NA	NA	NA
WP_139750788.1\|1448443_1449463_+	hypothetical protein	NA	NA	NA	NA
WP_005330555.1\|1449459_1450068_+	hypothetical protein	NA	NA	NA	NA
WP_041206912.1\|1450067_1452827_+	hypothetical protein	NA	NA	NA	NA
WP_021140990.1\|1452823_1453696_+	hypothetical protein	NA	NA	NA	NA
WP_021140991.1\|1453851_1454796_+	hypothetical protein	NA	NA	NA	NA
WP_005330548.1\|1455105_1456929_+	DNA recombination protein RmuC	NA	NA	NA	NA
WP_099369133.1\|1457221_1457611_+	hypothetical protein	NA	NA	NA	NA
WP_005330546.1\|1457923_1458508_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_041205615.1\|1458504_1461075_+	DEAD/DEAH box helicase family protein	A0A097BY72	Enterococcus_phage	4.1e-32	30.5
WP_005330541.1\|1461183_1462401_-	J domain-containing protein	NA	NA	NA	NA
WP_005329232.1\|1463078_1464389_-	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_005329233.1\|1464388_1464643_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_010674978.1\|1465144_1465393_+	hypothetical protein	NA	NA	NA	NA
WP_010674977.1\|1465813_1466065_-	plasmid stabilization protein	NA	NA	NA	NA
WP_041206913.1\|1466143_1467502_-	Fic family protein	NA	NA	NA	NA
WP_041205616.1\|1467705_1468158_+	DUF2384 domain-containing protein	NA	NA	NA	NA
1468583:1468642	attL	NA	NA	NA	NA
WP_041204928.1\|1468718_1469846_+\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
1468583:1468642	attL	NA	NA	NA	NA
WP_148304691.1\|1469821_1470361_+	hypothetical protein	NA	NA	NA	NA
WP_041205618.1\|1470353_1472732_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_005327392.1\|1472716_1476025_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_005327394.1\|1476227_1477151_-	WYL domain-containing protein	NA	NA	NA	NA
WP_041205619.1\|1477251_1477542_+	DUF4258 domain-containing protein	NA	NA	NA	NA
WP_041206914.1\|1477926_1478187_+	ADP-ribosylglycohydrolase	NA	NA	NA	NA
WP_059169687.1\|1478303_1478516_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_042011229.1\|1478639_1478849_+	hypothetical protein	NA	NA	NA	NA
WP_005327400.1\|1478860_1480099_+\|integrase	site-specific integrase	A0A1W6JTA0	Pseudomonas_phage	3.9e-36	29.5
WP_069785115.1\|1480082_1480973_+	HDOD domain-containing protein	NA	NA	NA	NA
WP_041205620.1\|1481104_1482442_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_041205621.1\|1482778_1483726_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	5.6e-43	36.4
WP_041205622.1\|1483840_1484983_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_148304692.1\|1485118_1485664_-	hypothetical protein	NA	NA	NA	NA
WP_041205625.1\|1487112_1487457_-	hypothetical protein	NA	NA	NA	NA
WP_143237846.1\|1488080_1489097_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.1
1487086:1488137	attR	NA	NA	NA	NA
WP_148304693.1\|1490276_1490873_+	hypothetical protein	NA	NA	NA	NA
1487086:1488137	attR	NA	NA	NA	NA
WP_041205384.1\|1491649_1492747_-\|transposase	ISAs1-like element ISAeme2 family transposase	NA	NA	NA	NA
WP_041205628.1\|1494315_1495350_-	hypothetical protein	NA	NA	NA	NA
WP_041205629.1\|1495549_1496497_-\|transposase	IS30-like element ISAeme18 family transposase	H7BVY4	unidentified_phage	1.1e-30	32.6
WP_081805681.1\|1496536_1496848_-	single-stranded DNA-binding protein	A0A291LCB6	Klebsiella_phage	1.3e-25	69.3
WP_005330391.1\|1497099_1498359_-	translesion error-prone DNA polymerase V subunit UmuC	F1C5A5	Cronobacter_phage	2.7e-117	52.9
WP_041206919.1\|1498339_1498783_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A218MND2	uncultured_virus	1.3e-26	51.2
WP_076611394.1\|1499333_1500536_-\|transposase	ISL3-like element ISAeme19 family transposase	A9YX10	Burkholderia_phage	1.0e-102	53.2
WP_081805682.1\|1500694_1501216_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_005325951.1\|1501260_1502322_-\|transposase	IS701-like element ISAeme11 family transposase	NA	NA	NA	NA
WP_081805683.1\|1502389_1502707_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	9.7e-08	50.0
WP_148304732.1\|1502934_1503351_+	hypothetical protein	NA	NA	NA	NA
WP_081805684.1\|1503681_1504701_+	DUF4007 family protein	NA	NA	NA	NA
WP_005330373.1\|1504702_1508008_+	hypothetical protein	NA	NA	NA	NA
WP_049832176.1\|1508000_1508921_+	phosphoadenosine phosphosulfate reductase family protein	A0A0F7L647	uncultured_marine_virus	3.9e-25	35.3
WP_005330377.1\|1508973_1511319_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_005330379.1\|1511321_1513484_+	DEAD/DEAH box helicase family protein	A0A2H4UTW8	Bodo_saltans_virus	2.4e-09	22.7
WP_041205634.1\|1513483_1513714_+	hypothetical protein	NA	NA	NA	NA
WP_005330381.1\|1513694_1515755_+	AAA family ATPase	NA	NA	NA	NA
WP_041205635.1\|1515747_1516203_+	hypothetical protein	NA	NA	NA	NA
WP_081805685.1\|1516195_1517245_+	cysteine desulfurase	NA	NA	NA	NA
WP_005330384.1\|1517269_1519294_-	DNA phosphorothioation-associated putative methyltransferase	NA	NA	NA	NA
WP_158319060.1\|1519293_1519830_-	hypothetical protein	NA	NA	NA	NA
WP_041205636.1\|1519971_1523172_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_005326705.1\|1523168_1525559_-	hypothetical protein	NA	NA	NA	NA
WP_081805686.1\|1525551_1526130_-	hypothetical protein	NA	NA	NA	NA
WP_005326701.1\|1526373_1527606_-	J domain-containing protein	NA	NA	NA	NA
WP_005326697.1\|1528349_1529207_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	2.3e-27	32.2
WP_005326695.1\|1529307_1530471_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_041205638.1\|1530571_1531600_-	isopenicillin N synthase family oxygenase	NA	NA	NA	NA
WP_005326691.1\|1531997_1532636_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_005326689.1\|1532737_1533640_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005326687.1\|1533699_1534440_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_139750670.1\|1534627_1535593_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_041205641.1\|1535861_1538006_+	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_041206923.1\|1538098_1538890_+	siderophore ferric iron reductase	NA	NA	NA	NA
WP_041205051.1\|1538934_1540272_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
1549854:1549870	attR	NA	NA	NA	NA

DBSCAN-SWA_14

1607845 : 1657167

Bacillus_phage(18.18%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010676219.1\|1607845_1608943_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_041206924.1\|1609083_1609674_-	CoA pyrophosphatase	NA	NA	NA	NA
WP_049832177.1\|1609729_1611106_-	aminodeoxychorismate synthase component I	A0A0B5J984	Pandoravirus	2.4e-47	43.6
WP_005323523.1\|1611315_1612839_+	fumarate hydratase	NA	NA	NA	NA
WP_005323524.1\|1612999_1613479_-	hypothetical protein	NA	NA	NA	NA
WP_005323525.1\|1613712_1613910_+	DUF4250 domain-containing protein	NA	NA	NA	NA
WP_005323527.1\|1614306_1616781_+	glycogen/starch/alpha-glucan phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	2.0e-15	45.6
WP_005323528.1\|1616845_1617400_-	cytochrome b/b6 domain-containing protein	NA	NA	NA	NA
WP_005323530.1\|1617701_1619087_-	DASS family sodium-coupled anion symporter	NA	NA	NA	NA
WP_041205674.1\|1619241_1619682_-	thioredoxin TrxC	A0A1J0GW78	Streptomyces_phage	2.6e-11	40.4
WP_005323534.1\|1619836_1622635_+	response regulator	A0A1V0SGX0	Hokovirus	1.3e-66	34.0
WP_041205675.1\|1622778_1624515_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	2.9e-53	31.4
WP_005323542.1\|1624624_1626376_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	3.7e-48	30.5
WP_005323552.1\|1626437_1627619_-	hypothetical protein	NA	NA	NA	NA
WP_004576012.1\|1628180_1629599_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_041204928.1\|1629616_1630744_+\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_041205678.1\|1630719_1631910_+\|transposase	transposase	A0A077SLN2	Escherichia_phage	3.7e-145	68.1
WP_005324917.1\|1632209_1632683_+	DUF4442 domain-containing protein	NA	NA	NA	NA
WP_005324920.1\|1632755_1632989_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_005324922.1\|1633179_1633584_-	MaoC family dehydratase	NA	NA	NA	NA
WP_005324924.1\|1633580_1635365_-	class I poly(R)-hydroxyalkanoic acid synthase	NA	NA	NA	NA
WP_041205680.1\|1635457_1635808_-	phasin family protein	NA	NA	NA	NA
WP_005324927.1\|1636108_1636672_+	hypothetical protein	NA	NA	NA	NA
WP_041205682.1\|1636750_1637506_+	DUF429 domain-containing protein	NA	NA	NA	NA
WP_041205684.1\|1637842_1638718_+	pyridoxal kinase PdxY	NA	NA	NA	NA
WP_041205686.1\|1638756_1639050_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_005324932.1\|1639736_1640582_+	deoxyribonuclease IV	A0A1V0SCI4	Indivirus	6.1e-17	25.3
WP_041205689.1\|1640656_1641646_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_005324936.1\|1641714_1642605_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_041205690.1\|1642708_1643689_+	TDT family transporter	NA	NA	NA	NA
WP_041205691.1\|1643914_1644904_+	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase	NA	NA	NA	NA
WP_041206926.1\|1645056_1646052_+	lipid A biosynthesis acyltransferase	NA	NA	NA	NA
WP_005324946.1\|1646236_1647097_+	RIO1 protein	NA	NA	NA	NA
WP_005324950.1\|1648620_1649253_-	hypothetical protein	NA	NA	NA	NA
WP_005324952.1\|1649437_1651867_+	DNA polymerase II	L7TKF2	Halovirus	6.3e-30	27.1
WP_041205696.1\|1652614_1653994_-	MATE family efflux transporter	NA	NA	NA	NA
WP_005324956.1\|1654145_1654352_-	YaeP family protein	NA	NA	NA	NA
WP_005324958.1\|1654488_1655106_+	riboflavin synthase	NA	NA	NA	NA
WP_010674034.1\|1655478_1655883_-\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	6.7e-30	54.8
WP_021141234.1\|1655940_1657167_+\|transposase	transposase	O80301	Enterobacteria_phage	7.7e-154	78.6

DBSCAN-SWA_15

1661708 : 1729087

Vibrio_phage(16.67%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005323562.1\|1661708_1662626_+\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-101	59.5
WP_005331648.1\|1662707_1662884_-	hypothetical protein	NA	NA	NA	NA
WP_005331650.1\|1663044_1663233_-	DUF4250 domain-containing protein	NA	NA	NA	NA
WP_005331665.1\|1663229_1663700_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005331682.1\|1665354_1666230_+	nucleotide-binding protein	NA	NA	NA	NA
WP_005331684.1\|1666231_1666543_+	DUF1289 domain-containing protein	NA	NA	NA	NA
WP_005331685.1\|1666588_1666912_-	YciU family protein	NA	NA	NA	NA
WP_005331687.1\|1667199_1667976_-	monofunctional biosynthetic peptidoglycan transglycosylase	NA	NA	NA	NA
WP_041205707.1\|1667960_1668287_-	YciU family protein	NA	NA	NA	NA
WP_041205708.1\|1668465_1668735_-	cell division topological specificity factor MinE	NA	NA	NA	NA
WP_005331693.1\|1668737_1669550_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_041205710.1\|1669568_1670288_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_041205712.1\|1670394_1670673_+	YcgL domain-containing protein	NA	NA	NA	NA
WP_005331699.1\|1670672_1671632_+	lytic murein transglycosylase	NA	NA	NA	NA
WP_041204923.1\|1671786_1672929_+\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_005325119.1\|1673107_1674478_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_041205714.1\|1674764_1676147_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_005325124.1\|1676313_1676598_-	pyrimidine/purine nucleoside phosphorylase	NA	NA	NA	NA
WP_041205716.1\|1676868_1678113_+	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_005325128.1\|1678197_1678596_-	MerR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_005325129.1\|1678728_1679892_+	acetyl-CoA C-acyltransferase	NA	NA	NA	NA
WP_041205719.1\|1680342_1681647_+	outer membrane protein transport protein	NA	NA	NA	NA
WP_041205722.1\|1681718_1682942_-	EAL domain-containing protein	NA	NA	NA	NA
WP_005325136.1\|1683056_1684313_-	outer membrane protein transport protein	NA	NA	NA	NA
WP_005325138.1\|1684564_1685836_-	outer membrane protein transport protein	NA	NA	NA	NA
WP_005325140.1\|1686244_1686988_-	DUF3379 domain-containing protein	NA	NA	NA	NA
WP_041206927.1\|1687611_1689132_-	BatD family protein	NA	NA	NA	NA
WP_005325155.1\|1690657_1691617_-	VWA domain-containing protein	NA	NA	NA	NA
WP_041205724.1\|1691613_1692177_-	DUF4381 domain-containing protein	NA	NA	NA	NA
WP_041205726.1\|1692161_1693052_-	DUF58 domain-containing protein	NA	NA	NA	NA
WP_005325158.1\|1693175_1694126_-	AAA family ATPase	NA	NA	NA	NA
WP_005325159.1\|1694320_1695631_+	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_041206928.1\|1695630_1697778_+	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_005325161.1\|1698053_1698194_+	TIGR02808 family protein	NA	NA	NA	NA
WP_005325163.1\|1698384_1698942_+	YaeQ family protein	NA	NA	NA	NA
WP_005325165.1\|1698954_1699839_+	AEC family transporter	NA	NA	NA	NA
WP_148304695.1\|1700122_1700374_-\|bacteriocin	class IIc cyclic bacteriocin	NA	NA	NA	NA
WP_005325170.1\|1701079_1702696_-\|transposase	IS66-like element ISAeme5 family transposase	A0A218MNE7	uncultured_virus	4.7e-42	32.8
WP_041205730.1\|1702744_1703110_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_005325174.1\|1703109_1703412_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_041205731.1\|1705424_1706693_-\|transposase	IS4-like element ISAeme3 family transposase	NA	NA	NA	NA
WP_041206933.1\|1707149_1708379_-	MFS transporter	NA	NA	NA	NA
WP_005326120.1\|1708440_1709211_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.4e-12	24.6
WP_005326119.1\|1709203_1710256_-	iron ABC transporter permease	NA	NA	NA	NA
WP_005326118.1\|1710353_1711475_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005326114.1\|1715408_1715948_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_005326113.1\|1716295_1717918_+	acyl-CoA synthetase	A0A2H4PQU7	Staphylococcus_phage	2.8e-26	25.0
WP_005326112.1\|1718127_1718826_+	WYL domain-containing protein	NA	NA	NA	NA
WP_005326111.1\|1718892_1719213_+	hypothetical protein	NA	NA	NA	NA
WP_041205732.1\|1719301_1719937_-	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE	A0A2H4UVM0	Bodo_saltans_virus	7.9e-17	34.2
WP_041205733.1\|1719929_1720703_-	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_005326105.1\|1720879_1724848_-	PAS domain S-box protein	A0A1V0SGX0	Hokovirus	1.9e-52	35.6
WP_041205734.1\|1724844_1726995_-	PAS domain S-box protein	NA	NA	NA	NA
WP_021141311.1\|1727950_1729087_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA

DBSCAN-SWA_16

1746911 : 1821096

Catovirus(16.67%)

tRNA,transposase,protease,integrase

attL 1738475:1738491|attR 1819578:1819594

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1738475:1738491	attL	NA	NA	NA	NA
WP_041205743.1\|1746911_1747856_-\|tRNA	tRNA dihydrouridine(16) synthase DusC	NA	NA	NA	NA
WP_041205744.1\|1748033_1748411_+	YbaN family protein	NA	NA	NA	NA
WP_005327012.1\|1748543_1749089_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	9.1e-30	41.5
WP_041205745.1\|1749262_1751782_+	DNA polymerase III subunit gamma/tau	E7DN81	Pneumococcus_phage	7.9e-44	39.4
WP_011706069.1\|1751912_1752242_+	YbaB/EbfC family nucleoid-associated protein	NA	NA	NA	NA
WP_005330657.1\|1752768_1753395_-	hydrolase	NA	NA	NA	NA
WP_005330651.1\|1753559_1754426_-	pirin family protein	NA	NA	NA	NA
WP_005330648.1\|1754523_1755414_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_005330645.1\|1755497_1756820_-	YjiH family protein	NA	NA	NA	NA
WP_041205601.1\|1757170_1758121_-\|transposase	IS1595-like element ISAeca5 family transposase	NA	NA	NA	NA
WP_005325086.1\|1759568_1759991_+	CBS domain-containing protein	NA	NA	NA	NA
WP_005325088.1\|1760168_1764095_+	ATP-dependent RNA helicase HrpA	A0A1V0SBU4	Catovirus	1.8e-55	27.6
WP_041205747.1\|1764193_1765036_+	hypothetical protein	NA	NA	NA	NA
WP_041205748.1\|1765199_1765487_+	50S ribosomal protein L25	NA	NA	NA	NA
WP_041205750.1\|1765690_1768861_+	hybrid sensor histidine kinase/response regulator	A0A1V0SGX0	Hokovirus	3.6e-62	31.3
WP_004576012.1\|1769513_1770932_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_005328331.1\|1771387_1772032_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_005328332.1\|1772025_1773156_-\|tRNA	tRNA 2-selenouridine(34) synthase MnmH	NA	NA	NA	NA
WP_041205752.1\|1773208_1774246_-	selenide, water dikinase SelD	NA	NA	NA	NA
WP_005328336.1\|1774574_1775219_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_005328337.1\|1775632_1776826_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_005328340.1\|1777039_1778470_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	6.5e-19	33.3
WP_005328342.1\|1778553_1778826_+	acylphosphatase	NA	NA	NA	NA
WP_148304733.1\|1778848_1779589_+	CHAD domain-containing protein	NA	NA	NA	NA
WP_041205755.1\|1779656_1781690_-\|tRNA	methionine--tRNA ligase	A0A1V0SEZ7	Hokovirus	1.1e-43	26.1
WP_005328348.1\|1781875_1782958_+	iron-sulfur cluster carrier protein ApbC	NA	NA	NA	NA
WP_041205758.1\|1783066_1783711_+	uridine kinase	A0A1V0SAA3	Catovirus	3.0e-32	38.0
WP_005328350.1\|1783774_1784356_+	dCTP deaminase	I4AZP2	Saccharomonospora_phage	9.1e-28	39.5
WP_041205760.1\|1784704_1786177_+	inorganic phosphate transporter	NA	NA	NA	NA
WP_005327996.1\|1787841_1789260_-\|transposase	IS66-like element ISUnCu16 family transposase	NA	NA	NA	NA
WP_041205761.1\|1792100_1795283_-	ribonuclease E	NA	NA	NA	NA
WP_041205763.1\|1795657_1796641_+	23S rRNA pseudouridine(955/2504/2580) synthase RluC	NA	NA	NA	NA
WP_005329555.1\|1796640_1797288_+	HAD-IA family hydrolase	NA	NA	NA	NA
WP_041205765.1\|1797360_1797942_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_041205768.1\|1798086_1798740_+	hypothetical protein	NA	NA	NA	NA
WP_025326977.1\|1799010_1799532_+	23S rRNA accumulation protein YceD	NA	NA	NA	NA
WP_005300935.1\|1799552_1799720_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_041205769.1\|1799729_1800749_+	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_005329561.1\|1800755_1801715_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_041205773.1\|1801781_1802717_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_005329563.1\|1802730_1803465_+	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	5.7e-19	34.7
WP_005300909.1\|1803622_1803859_+	acyl carrier protein	B2ZXV3	Ralstonia_phage	1.7e-09	47.1
WP_041205775.1\|1803941_1805183_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_042648387.1\|1805250_1806057_+	aminodeoxychorismate lyase	NA	NA	NA	NA
WP_005329567.1\|1806046_1807048_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_041205780.1\|1807047_1807689_+	dTMP kinase	A0A1L2BX49	Bacteriophage	8.2e-30	42.4
WP_005329570.1\|1807673_1808621_+	DNA polymerase III subunit delta'	B2ZY37	Ralstonia_phage	3.5e-05	27.5
WP_005329573.1\|1808639_1809419_+	YchF/TatD family DNA exonuclease	NA	NA	NA	NA
WP_005329575.1\|1809745_1810735_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_005329577.1\|1810898_1811183_+	hypothetical protein	NA	NA	NA	NA
WP_041205785.1\|1811417_1812848_-	16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF	NA	NA	NA	NA
WP_041205787.1\|1812976_1815529_-	MCE family protein	NA	NA	NA	NA
WP_041205789.1\|1815580_1816189_-	paraquat-inducible protein A	NA	NA	NA	NA
WP_005329583.1\|1816166_1816811_-	paraquat-inducible protein A	NA	NA	NA	NA
WP_005329584.1\|1817031_1817337_+	YebG family protein	NA	NA	NA	NA
WP_041205791.1\|1817617_1818913_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_005329587.1\|1819119_1821096_+\|protease	Lon protease family protein	NA	NA	NA	NA
1819578:1819594	attR	NA	NA	NA	NA

DBSCAN-SWA_17

1866345 : 1877469

Hokovirus(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041206943.1\|1866345_1870272_-	transporter substrate-binding domain-containing protein	A0A1V0SGX0	Hokovirus	4.1e-31	35.6
WP_005300715.1\|1870326_1870623_-	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	3.0e-11	35.6
WP_005329693.1\|1870626_1873014_-\|tRNA	phenylalanine--tRNA ligase subunit beta	A0A1L3IZU3	BeAn_58058_virus	1.1e-05	24.5
WP_005329694.1\|1873026_1874010_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	5.3e-36	38.2
WP_010674800.1\|1874334_1874691_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_005315535.1\|1874705_1874903_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_041204270.1\|1874988_1875537_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	1.8e-14	37.2
WP_041205812.1\|1875540_1877469_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	9.7e-127	38.0

DBSCAN-SWA_18

2091443 : 2154255

uncultured_Mediterranean_phage(14.29%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005325367.1\|2091443_2092202_-\|tRNA	tRNA-(ms[2]io[6]A)-hydroxylase	NA	NA	NA	NA
WP_041206958.1\|2092330_2093341_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_005325369.1\|2093594_2095049_+	PTS cellobiose/arbutin/salicin transporter subunit IIBC	NA	NA	NA	NA
WP_005325370.1\|2095082_2096513_+	6-phospho-beta-glucosidase	A0A0B5JD41	Pandoravirus	7.7e-36	27.0
WP_005325371.1\|2096603_2098124_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.8e-88	42.6
WP_005325372.1\|2098142_2098634_-	CvpA family protein	NA	NA	NA	NA
WP_005325374.1\|2098822_2100118_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	6.2e-93	50.7
WP_167332171.1\|2100406_2101744_-	AAA family ATPase	G3MBE0	Bacillus_virus	1.7e-77	41.0
WP_041205890.1\|2101896_2102505_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_041205892.1\|2102574_2105079_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	1.6e-89	49.6
WP_005300047.1\|2105271_2105763_-	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_041205894.1\|2105913_2107029_+	alanine dehydrogenase	NA	NA	NA	NA
WP_005325390.1\|2107213_2108164_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	4.6e-61	44.2
WP_041205896.1\|2108220_2109462_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	2.2e-15	31.6
WP_005325399.1\|2109563_2110034_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_005325401.1\|2110051_2110759_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_041205898.1\|2110755_2111472_+	arginyltransferase	NA	NA	NA	NA
WP_106886977.1\|2111498_2111759_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_005325408.1\|2111828_2114081_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	9.2e-169	43.5
WP_005325410.1\|2114141_2114459_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	46.9
WP_005300025.1\|2114687_2114906_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.2e-17	63.2
WP_005325413.1\|2115031_2116144_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_041204923.1\|2116423_2117566_+\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_005326802.1\|2117743_2118058_+	quaternary ammonium compound efflux SMR transporter SugE	NA	NA	NA	NA
WP_041205901.1\|2118138_2118837_-	B3/4 domain-containing protein	NA	NA	NA	NA
WP_041205902.1\|2119147_2120908_+	30S ribosomal protein S12 methylthiotransferase accessory factor YcaO	NA	NA	NA	NA
WP_005326809.1\|2121289_2122138_+	formate transporter FocA	NA	NA	NA	NA
WP_041206959.1\|2122179_2124462_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	4.0e-164	42.7
WP_005326813.1\|2124997_2125453_-	YcgN family cysteine cluster protein	NA	NA	NA	NA
WP_139750789.1\|2125795_2126008_+	hypothetical protein	NA	NA	NA	NA
WP_041205253.1\|2126260_2127598_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005326945.1\|2127653_2128526_-	succinate--CoA ligase subunit alpha	NA	NA	NA	NA
WP_005326943.1\|2128525_2129692_-	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_005326941.1\|2129798_2130986_-	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
WP_041205906.1\|2131078_2133889_-	2-oxoglutarate dehydrogenase E1 component	NA	NA	NA	NA
WP_025326736.1\|2134003_2134720_-	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_025326735.1\|2134737_2136504_-	succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
WP_005326929.1\|2136505_2136850_-	succinate dehydrogenase, hydrophobic membrane anchor protein	NA	NA	NA	NA
WP_025326734.1\|2136843_2137233_-	succinate dehydrogenase cytochrome b556 subunit	NA	NA	NA	NA
WP_041205909.1\|2137656_2138943_+	citrate synthase	NA	NA	NA	NA
WP_005326919.1\|2139038_2139353_+	DUF4377 domain-containing protein	NA	NA	NA	NA
WP_005326918.1\|2139447_2139942_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_041205911.1\|2140004_2141216_-	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_162472484.1\|2141306_2143331_+\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_005326913.1\|2143397_2144003_-	DUF922 domain-containing protein	NA	NA	NA	NA
WP_158319061.1\|2144060_2144210_-	hypothetical protein	NA	NA	NA	NA
WP_049832182.1\|2144248_2144623_-	hypothetical protein	NA	NA	NA	NA
WP_158319062.1\|2144677_2145811_+	ATPase	A0A1B0Z1F4	Shewanella_phage	5.1e-27	27.9
WP_004576012.1\|2147249_2148668_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_021141277.1\|2151913_2152669_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.4e-52	45.4
WP_021141278.1\|2152692_2154255_-\|transposase	IS21-like element ISAs28 family transposase	K4I413	Acidithiobacillus_phage	9.6e-125	46.0

DBSCAN-SWA_19

2402507 : 2494102

Staphylococcus_prophage(21.05%)

tRNA,transposase,integrase

attL 2465734:2465793|attR 2491269:2492360

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021141311.1\|2402507_2403644_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_148304699.1\|2403836_2404529_+	hypothetical protein	NA	NA	NA	NA
WP_099993964.1\|2404538_2405555_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_019706001.1\|2405906_2406854_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_021141311.1\|2406919_2408056_-\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_004576012.1\|2409873_2411292_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_005330901.1\|2411913_2413290_-\|tRNA	cysteine--tRNA ligase	H2EDD6	Moumouvirus	1.0e-45	30.0
WP_005330899.1\|2413493_2413991_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_005330897.1\|2413980_2414694_+	DUF4269 domain-containing protein	NA	NA	NA	NA
WP_005330895.1\|2414690_2415419_+	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_005330893.1\|2415539_2415788_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_041205997.1\|2415994_2416618_-	glutathione S-transferase	NA	NA	NA	NA
WP_158319064.1\|2416958_2417588_-	Ig-like domain-containing protein	NA	NA	NA	NA
WP_041206992.1\|2417678_2418818_-\|transposase	transposase	A0A077SLN2	Escherichia_phage	6.1e-145	68.2
WP_005323562.1\|2419031_2419949_+\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-101	59.5
WP_041206994.1\|2421459_2422467_+	Fic family protein	D7RWK9	Brochothrix_phage	3.4e-06	24.2
WP_041204928.1\|2422808_2423936_+\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_005325880.1\|2424291_2424852_-	DUF2787 family protein	NA	NA	NA	NA
WP_148304700.1\|2424912_2425548_-	hypothetical protein	NA	NA	NA	NA
WP_025201450.1\|2425670_2425973_-	DUF1232 domain-containing protein	NA	NA	NA	NA
WP_041205999.1\|2425965_2426322_-	hypothetical protein	NA	NA	NA	NA
WP_041206000.1\|2426469_2427675_-\|integrase	site-specific integrase	Q19US1	Mannheimia_phage	2.2e-12	29.4
WP_041206001.1\|2428518_2429073_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_041206002.1\|2429366_2431220_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_041206003.1\|2431331_2431976_-	UvrY/SirA/GacA family response regulator transcription factor	NA	NA	NA	NA
WP_005331986.1\|2432186_2432936_-	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_005331987.1\|2432932_2433133_-	Trm112 family protein	NA	NA	NA	NA
WP_005331989.1\|2433283_2434279_-	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_005331991.1\|2434278_2436048_-	lipid A ABC transporter ATP-binding protein/permease MsbA	W8CYL7	Bacillus_phage	4.2e-60	30.5
WP_148304701.1\|2439804_2441234_-\|transposase	IS66-like element ISAeme24 family transposase	NA	NA	NA	NA
WP_041205080.1\|2441742_2442942_-	acetate kinase	NA	NA	NA	NA
WP_041206006.1\|2443268_2443739_-	YhcH/YjgK/YiaL family protein	NA	NA	NA	NA
WP_041206007.1\|2444039_2445146_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_041206008.1\|2445355_2445907_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005327996.1\|2446264_2447683_+\|transposase	IS66-like element ISUnCu16 family transposase	NA	NA	NA	NA
WP_004576012.1\|2449177_2450596_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_049832193.1\|2451087_2452764_-	H-NS histone family protein	NA	NA	NA	NA
WP_041201465.1\|2452779_2453943_-	AAA family ATPase	NA	NA	NA	NA
WP_005331310.1\|2453972_2456957_-	Hsp70 family protein	E3T5H4	Cafeteria_roenbergensis_virus	2.7e-19	24.2
WP_010676221.1\|2457279_2457459_-	hypothetical protein	NA	NA	NA	NA
WP_041206012.1\|2459271_2460834_+\|transposase	IS21-like element ISAs28 family transposase	K4I413	Acidithiobacillus_phage	3.3e-125	46.2
WP_081805714.1\|2460857_2461223_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	1.5e-12	42.1
WP_004576012.1\|2461287_2462706_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_019706001.1\|2463542_2464490_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_041206013.1\|2464767_2465169_-	H-NS histone family protein	NA	NA	NA	NA
WP_081805717.1\|2465240_2465771_-	inovirus Gp2 family protein	NA	NA	NA	NA
2465734:2465793	attL	NA	NA	NA	NA
WP_012564931.1\|2465838_2466786_+\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_005331303.1\|2467133_2467847_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_041206014.1\|2467846_2470978_-	HsdR family type I site-specific deoxyribonuclease	A0A220A398	Liberibacter_phage	6.8e-53	28.1
WP_041206015.1\|2471052_2472117_-	macro domain-containing protein	A0A2I7QNM6	Vibrio_phage	2.9e-24	40.5
WP_005331300.1\|2472113_2472767_-	DUF4433 domain-containing protein	NA	NA	NA	NA
WP_005331298.1\|2473033_2473177_-	hypothetical protein	NA	NA	NA	NA
WP_041206016.1\|2474166_2475435_+\|transposase	IS4-like element ISAeme4 family transposase	NA	NA	NA	NA
WP_017411290.1\|2475693_2476911_-	tetracycline efflux MFS transporter Tet(E)	NA	NA	NA	NA
WP_017411289.1\|2476991_2477624_+	tetracycline resistance transcriptional repressor TetR(E)	NA	NA	NA	NA
WP_158319065.1\|2478010_2478136_-	hypothetical protein	NA	NA	NA	NA
WP_147273949.1\|2478165_2478996_-	hypothetical protein	NA	NA	NA	NA
WP_005323888.1\|2479158_2479419_+	hypothetical protein	NA	NA	NA	NA
WP_041206017.1\|2479472_2479877_-\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	1.4e-30	55.6
WP_041206018.1\|2479934_2481161_+\|transposase	transposase	O80301	Enterobacteria_phage	1.3e-153	78.6
WP_041206019.1\|2481296_2481548_+	DUF4160 domain-containing protein	NA	NA	NA	NA
WP_041206020.1\|2481531_2481954_+	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_005324832.1\|2482348_2482531_+	Rop family plasmid primer RNA-binding protein	NA	NA	NA	NA
WP_041206021.1\|2482863_2483151_+	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_041206022.1\|2483138_2483432_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_147273935.1\|2483584_2483872_+	hypothetical protein	NA	NA	NA	NA
WP_081805719.1\|2484093_2484612_+	topoisomerase DNA-binding C4 zinc finger domain-containing protein	NA	NA	NA	NA
WP_041206016.1\|2485350_2486619_+\|transposase	IS4-like element ISAeme4 family transposase	NA	NA	NA	NA
WP_158319066.1\|2486953_2487964_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_041206024.1\|2487956_2489720_+	hypothetical protein	NA	NA	NA	NA
WP_012564931.1\|2490275_2491223_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_005332003.1\|2491304_2492744_+	hypothetical protein	A0A2H4J185	uncultured_Caudovirales_phage	4.7e-09	24.9
2491269:2492360	attR	NA	NA	NA	NA
WP_011191341.1\|2492827_2494102_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_20

2498880 : 2553370

Planktothrix_phage(28.57%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004576012.1\|2498880_2500299_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_088813959.1\|2500420_2501981_+\|transposase	IS3-like element ISAs20 family transposase	NA	NA	NA	NA
WP_081805894.1\|2501911_2502742_-	ComEC/Rec2 family competence protein	NA	NA	NA	NA
WP_005331307.1\|2502770_2503289_+	DUF2062 domain-containing protein	NA	NA	NA	NA
WP_005331306.1\|2503282_2503777_+	DUF2062 domain-containing protein	NA	NA	NA	NA
WP_005331305.1\|2503903_2505409_+	DUF853 family protein	A0A248XCZ8	Klebsiella_phage	8.5e-86	46.4
WP_041205051.1\|2505457_2506795_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005329100.1\|2507007_2508198_-	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_005329096.1\|2508343_2509285_-	hypothetical protein	NA	NA	NA	NA
WP_005329094.1\|2509487_2510525_-	porin	NA	NA	NA	NA
WP_005329092.1\|2510910_2512983_+	ATP-dependent DNA helicase DinG	A0A127AW80	Bacillus_phage	2.7e-42	27.2
WP_005329090.1\|2513127_2513787_+	DUF2057 domain-containing protein	NA	NA	NA	NA
WP_005329089.1\|2513860_2514757_+	histone deacetylase	A0A2K9KZC4	Tupanvirus	1.4e-11	25.6
WP_041206030.1\|2514916_2516065_-	MFS transporter	NA	NA	NA	NA
WP_041206031.1\|2516306_2517257_-	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
WP_041206032.1\|2517583_2518975_+	alkaline phosphatase	NA	NA	NA	NA
WP_005329077.1\|2518998_2520366_+	alkaline phosphatase	NA	NA	NA	NA
WP_041206033.1\|2520416_2521100_+	hypothetical protein	NA	NA	NA	NA
WP_193354199.1\|2521183_2521918_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_041206035.1\|2522144_2522540_+	nucleoside diphosphate kinase regulator	NA	NA	NA	NA
WP_005329071.1\|2522756_2523347_+	transcriptional regulator UhpA	NA	NA	NA	NA
WP_005329069.1\|2523343_2524864_+	signal transduction histidine-protein kinase/phosphatase UhpB	NA	NA	NA	NA
WP_041206036.1\|2524885_2526220_+	MFS transporter	NA	NA	NA	NA
WP_021141234.1\|2527043_2528270_-\|transposase	transposase	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_021141233.1\|2528327_2528732_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	8.8e-30	54.8
WP_005330342.1\|2529635_2530424_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_005330345.1\|2530521_2531481_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_041206038.1\|2531570_2532314_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.0e-36	38.7
WP_041207009.1\|2532514_2533354_+	sterol desaturase family protein	NA	NA	NA	NA
WP_041205358.1\|2533473_2534802_+\|transposase	IS4-like element ISAeme12 family transposase	NA	NA	NA	NA
WP_005328837.1\|2534854_2536255_-	amino acid permease	NA	NA	NA	NA
WP_041206039.1\|2536264_2537164_-	homocysteine S-methyltransferase family protein	NA	NA	NA	NA
WP_005328832.1\|2537438_2537981_-	hypothetical protein	NA	NA	NA	NA
WP_041206040.1\|2538001_2539321_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_005328827.1\|2539513_2540224_-	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_005328825.1\|2540395_2541214_-	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.6e-22	32.1
WP_041206041.1\|2541321_2542971_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_041206042.1\|2542988_2545226_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_103244595.1\|2545410_2546839_+\|transposase	IS66-like element ISAeme23 family transposase	NA	NA	NA	NA
WP_081805723.1\|2546994_2547534_-\|tRNA	tRNA adenosine(34) deaminase TadA	NA	NA	NA	NA
WP_167332172.1\|2548141_2548282_+	hypothetical protein	NA	NA	NA	NA
WP_005325257.1\|2548985_2550593_+	malate synthase A	NA	NA	NA	NA
WP_005325258.1\|2550666_2551980_+	isocitrate lyase	NA	NA	NA	NA
WP_041205051.1\|2552032_2553370_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA

DBSCAN-SWA_21

2568829 : 2633456

Helicobacter_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_021141234.1\|2568829_2570056_-\|transposase	transposase	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_021141233.1\|2570113_2570518_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	8.8e-30	54.8
WP_041206863.1\|2572097_2573237_-\|transposase	transposase	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_041205574.1\|2573295_2573721_+\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_005329788.1\|2573961_2575170_-	flagellar hook-associated protein FlgL	NA	NA	NA	NA
WP_041206050.1\|2575173_2577171_-	flagellar hook protein FlgK	NA	NA	NA	NA
WP_005329786.1\|2577174_2578287_-	flagellar assembly peptidoglycan hydrolase FlgJ	A0A0A7RU71	Clostridium_phage	2.9e-14	35.0
WP_041206051.1\|2578333_2579431_-	flagellar basal body P-ring protein FlgI	NA	NA	NA	NA
WP_041206052.1\|2579492_2580164_-	flagellar basal body L-ring protein FlgH	NA	NA	NA	NA
WP_005329779.1\|2580190_2580979_-	flagellar basal-body rod protein FlgG	NA	NA	NA	NA
WP_005329778.1\|2580993_2581740_-	flagellar basal-body rod protein FlgF	NA	NA	NA	NA
WP_005329777.1\|2581886_2583263_-	flagellar hook protein FlgE	NA	NA	NA	NA
WP_005329776.1\|2583273_2584011_-	flagellar hook assembly protein FlgD	NA	NA	NA	NA
WP_005329775.1\|2584116_2584536_-	flagellar basal body rod protein FlgC	NA	NA	NA	NA
WP_005329774.1\|2584535_2584934_-	flagellar basal body rod protein FlgB	NA	NA	NA	NA
WP_005329773.1\|2584996_2585821_-	protein-glutamate O-methyltransferase	NA	NA	NA	NA
WP_025327540.1\|2585838_2586750_-	chemotaxis protein CheV	Q56AR1	Bacillus_thuringiensis_phage	1.7e-36	32.8
WP_081805725.1\|2586908_2587592_+	flagellar basal body P-ring formation protein FlgA	NA	NA	NA	NA
WP_005329758.1\|2587686_2588007_+	flagellar biosynthesis anti-sigma factor FlgM	NA	NA	NA	NA
WP_005329757.1\|2588003_2588420_+	flagellar protein FlgN	NA	NA	NA	NA
WP_005329754.1\|2588453_2589008_-	phosphodiesterase	NA	NA	NA	NA
WP_041207011.1\|2589018_2590656_-	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005329750.1\|2590955_2591858_+	DMT family transporter	NA	NA	NA	NA
WP_041206053.1\|2592039_2592732_-	16S rRNA pseudouridine(516) synthase RsuA	NA	NA	NA	NA
WP_081805727.1\|2592906_2593956_+	HD-GYP domain-containing protein	NA	NA	NA	NA
WP_021141234.1\|2593899_2595126_-\|transposase	transposase	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_021141233.1\|2595183_2595588_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	8.8e-30	54.8
WP_005331455.1\|2595879_2596068_-	hypothetical protein	NA	NA	NA	NA
WP_005331452.1\|2596282_2597176_+	EamA family transporter	NA	NA	NA	NA
WP_041206054.1\|2597268_2599119_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005331447.1\|2599423_2599816_-	DUF2750 domain-containing protein	NA	NA	NA	NA
WP_041206055.1\|2599910_2600468_-	hypothetical protein	NA	NA	NA	NA
WP_025327553.1\|2600716_2600965_+	TIGR02647 family protein	NA	NA	NA	NA
WP_041206056.1\|2600951_2601248_-	hypothetical protein	NA	NA	NA	NA
WP_005320244.1\|2601343_2601544_-	cold-shock protein	Q9AZD3	Lactococcus_phage	3.0e-15	59.4
WP_005331437.1\|2601758_2602859_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_005331436.1\|2602953_2603940_-	alpha-ketoacid dehydrogenase subunit beta	A0A0K0KW14	Prochlorococcus_phage	1.8e-07	28.8
WP_005331435.1\|2604008_2605106_-	pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha	NA	NA	NA	NA
WP_041206057.1\|2605367_2606384_-	succinylglutamate desuccinylase	NA	NA	NA	NA
WP_005331430.1\|2606656_2606866_-	DUF1127 domain-containing protein	NA	NA	NA	NA
WP_005331428.1\|2607389_2608283_+	DNA replication terminus site-binding protein	NA	NA	NA	NA
WP_005331425.1\|2608378_2612221_-	DEAD/DEAH box helicase	A0A160DHD3	Gordonia_phage	1.3e-45	28.8
WP_041206058.1\|2612438_2613092_-	DUF480 domain-containing protein	NA	NA	NA	NA
WP_148304737.1\|2613263_2613698_-	glycine zipper 2TM domain-containing protein	NA	NA	NA	NA
WP_049832195.1\|2613893_2615621_-	O-antigen ligase C-terminal domain-containing protein	NA	NA	NA	NA
WP_005331415.1\|2615708_2617793_-	YjbH domain-containing protein	NA	NA	NA	NA
WP_162472485.1\|2617789_2618479_-	capsule biosynthesis GfcC family protein	NA	NA	NA	NA
WP_041207014.1\|2618541_2619213_-	YjbF family lipoprotein	NA	NA	NA	NA
WP_041206060.1\|2619283_2619511_-	hypothetical protein	NA	NA	NA	NA
WP_088813959.1\|2619883_2621445_-\|transposase	IS3-like element ISAs20 family transposase	NA	NA	NA	NA
WP_041206061.1\|2622385_2624554_-	polysaccharide biosynthesis tyrosine autokinase	NA	NA	NA	NA
WP_041206062.1\|2624616_2625045_-	protein-tyrosine-phosphatase	NA	NA	NA	NA
WP_005327441.1\|2625280_2626402_-	polysaccharide biosynthesis/export family protein	NA	NA	NA	NA
WP_081805901.1\|2626689_2627397_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_139700378.1\|2627541_2628345_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_158319067.1\|2628383_2629109_-	glycosyltransferase	NA	NA	NA	NA
WP_148304704.1\|2629188_2629974_-	hypothetical protein	NA	NA	NA	NA
WP_099368881.1\|2630598_2631615_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_041206064.1\|2632418_2633456_-\|transposase	IS630-like element ISAeme16 family transposase	NA	NA	NA	NA

DBSCAN-SWA_22

2637400 : 2696424

Escherichia_phage(27.78%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205297.1\|2637400_2638675_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_148304705.1\|2638642_2638921_-	hypothetical protein	NA	NA	NA	NA
WP_005327996.1\|2639621_2641040_+\|transposase	IS66-like element ISUnCu16 family transposase	NA	NA	NA	NA
WP_005324204.1\|2641423_2642311_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	8.1e-28	34.7
WP_005324202.1\|2642310_2643396_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	2.2e-96	50.3
WP_041207018.1\|2644331_2645006_+	response regulator	W8CYM9	Bacillus_phage	2.8e-28	34.6
WP_041206069.1\|2645005_2646388_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_005324195.1\|2646734_2647703_-	glucokinase	NA	NA	NA	NA
WP_167332173.1\|2648051_2648906_+	transcriptional regulator HexR	NA	NA	NA	NA
WP_005324189.1\|2649066_2650506_+	pyruvate kinase	NA	NA	NA	NA
WP_041206070.1\|2650574_2651618_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_005324186.1\|2651633_2654696_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	2.5e-68	24.8
WP_005324184.1\|2654859_2657184_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_005324182.1\|2657231_2657885_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_005324180.1\|2658353_2659094_+	phosphatase	NA	NA	NA	NA
WP_099368881.1\|2660021_2661038_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_148304706.1\|2661104_2661311_+	hypothetical protein	NA	NA	NA	NA
WP_041206072.1\|2661589_2662717_+\|transposase	ISAs1-like element ISKpn9 family transposase	NA	NA	NA	NA
WP_158319068.1\|2662706_2663009_-	DUF4145 domain-containing protein	NA	NA	NA	NA
WP_171268792.1\|2663112_2663670_-	recombinase family protein	E5FFF9	Burkholderia_phage	6.0e-21	35.1
WP_005328266.1\|2663895_2664231_+	addiction module protein	A0A141GEX6	Brucella_phage	2.0e-11	46.4
WP_041206074.1\|2664236_2664551_+	DNA-binding protein	NA	NA	NA	NA
WP_041206077.1\|2666041_2666797_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.6e-59	51.5
WP_041206078.1\|2666811_2668353_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	2.5e-125	46.4
WP_041207020.1\|2669003_2670143_-\|transposase	transposase	A0A077SLN2	Escherichia_phage	6.1e-145	68.4
WP_041205574.1\|2670200_2670626_+\|transposase	IS200/IS605-like element ISAeme8 family transposase	A0A1S5RHE3	Helicobacter_phage	4.9e-23	46.9
WP_041206080.1\|2671189_2672605_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_041206081.1\|2672597_2675747_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_041206082.1\|2675764_2676958_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_005323466.1\|2677110_2677752_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_005323469.1\|2677851_2678511_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_005323470.1\|2678628_2679807_+	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_005323471.1\|2679881_2680745_-	acyl-CoA thioesterase II	NA	NA	NA	NA
WP_005323472.1\|2681000_2681924_-	23S rRNA pseudouridine(2605) synthase RluB	NA	NA	NA	NA
WP_005323473.1\|2682034_2682607_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	8.1e-21	36.3
WP_171268791.1\|2682642_2683524_-	segregation/condensation protein A	NA	NA	NA	NA
WP_005323475.1\|2683516_2684137_-	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_005323476.1\|2684266_2685148_-	PHP domain-containing protein	NA	NA	NA	NA
WP_005323477.1\|2685569_2687207_+	anthranilate synthase component 1	NA	NA	NA	NA
WP_005323478.1\|2687199_2687799_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-27	36.8
WP_005323479.1\|2687808_2688822_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	4.4e-54	38.7
WP_081805902.1\|2688881_2690306_+	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	3.7e-38	42.3
WP_005323481.1\|2690360_2691554_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_005323482.1\|2691550_2692357_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_041206084.1\|2692556_2693699_-\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA
WP_041206863.1\|2693875_2695015_-\|transposase	transposase	A0A077SLN2	Escherichia_phage	7.2e-146	68.7
WP_148304709.1\|2695048_2695408_+\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	3.2e-15	49.4
WP_019706001.1\|2695476_2696424_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7

DBSCAN-SWA_23

2716212 : 2760378

Enterobacteria_phage(20.0%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041207026.1\|2716212_2717541_+\|transposase	IS4-like element ISAeme13 family transposase	NA	NA	NA	NA
WP_041206092.1\|2717765_2718992_-\|transposase	transposase	O80301	Enterobacteria_phage	3.8e-153	78.3
WP_010674034.1\|2719049_2719454_+\|transposase	IS200/IS605-like element ISAs26 family transposase	A0A1S5RHE3	Helicobacter_phage	6.7e-30	54.8
WP_005327633.1\|2719546_2719927_-	DUF2069 domain-containing protein	NA	NA	NA	NA
WP_041206093.1\|2719923_2720274_-	arsenate reductase (glutaredoxin)	NA	NA	NA	NA
WP_041206094.1\|2720332_2720812_+	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_041206095.1\|2720882_2722316_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_005327624.1\|2722467_2722710_+	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_041206096.1\|2722790_2723861_+	AI-2E family transporter	NA	NA	NA	NA
WP_081805736.1\|2724046_2724721_+	MipA/OmpV family protein	NA	NA	NA	NA
WP_021141234.1\|2724664_2725891_-\|transposase	transposase	O80301	Enterobacteria_phage	7.7e-154	78.6
WP_005328150.1\|2726726_2727533_-	alpha/beta fold hydrolase	A0A2P1CHW5	Mycobacterium_phage	1.9e-07	25.7
WP_005328152.1\|2727785_2728601_+	polyphosphate kinase 2	NA	NA	NA	NA
WP_005328154.1\|2728709_2729846_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G3M9Y6	Bacillus_virus	4.7e-28	35.9
WP_025326477.1\|2729915_2730806_-	maltose ABC transporter permease MalG	NA	NA	NA	NA
WP_005328158.1\|2730818_2732471_-	maltose ABC transporter permease MalF	NA	NA	NA	NA
WP_005328161.1\|2732547_2733729_-	maltose/maltodextrin ABC transporter substrate-binding protein MalE	NA	NA	NA	NA
WP_005328162.1\|2734146_2735208_-	nucleoid-associated protein YejK	A0A1V0E8C0	Vibrio_phage	7.9e-62	39.8
WP_011705556.1\|2735281_2735509_+	DUF1414 domain-containing protein	NA	NA	NA	NA
WP_005328168.1\|2735552_2737400_+	DUF3413 domain-containing protein	NA	NA	NA	NA
WP_005328169.1\|2737661_2739812_+	TonB-dependent hemoglobin/transferrin/lactoferrin family receptor	NA	NA	NA	NA
WP_005328171.1\|2739811_2741851_+	S9 family peptidase	NA	NA	NA	NA
WP_041206097.1\|2741886_2744301_+	proprotein convertase P-domain-containing protein	NA	NA	NA	NA
WP_148304741.1\|2744363_2745722_+	DUF1566 domain-containing protein	NA	NA	NA	NA
WP_005328178.1\|2745718_2746276_+	DUF1566 domain-containing protein	NA	NA	NA	NA
WP_005328180.1\|2746463_2746946_+\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_005328181.1\|2747236_2747596_+	DUF413 domain-containing protein	NA	NA	NA	NA
WP_005328182.1\|2747595_2748471_+	HTH-type transcriptional regulator HdfR	NA	NA	NA	NA
WP_005328183.1\|2748537_2749677_-	bifunctional chorismate mutase/prephenate dehydrogenase	NA	NA	NA	NA
WP_005328184.1\|2749795_2750869_-	3-deoxy-7-phosphoheptulonate synthase	A0A0B6VT43	Edwardsiella_phage	6.1e-78	47.9
WP_041206098.1\|2751199_2752279_-	glycerophosphodiester phosphodiesterase	A0A220BY94	Staphylococcus_phage	9.3e-10	26.7
WP_005328189.1\|2752382_2753870_-	glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_005328190.1\|2754313_2755072_-	DeoR/GlpR family transcriptional regulator	A0A077SK06	Escherichia_phage	2.8e-21	28.2
WP_041206099.1\|2755172_2756543_-	glycerol-3-phosphate transporter	NA	NA	NA	NA
WP_041206100.1\|2756563_2757730_-\|transposase	transposase	A0A077SLN2	Escherichia_phage	2.5e-146	68.1
WP_010676219.1\|2758074_2759172_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_041206101.1\|2759235_2760378_+\|transposase	IS4-like element ISAs18 family transposase	NA	NA	NA	NA

DBSCAN-SWA_24

3246413 : 3297749

Staphylococcus_prophage(18.18%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099368881.1\|3246413_3247430_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_012564931.1\|3247839_3248787_-\|transposase	IS30-like element ISAeca1 family transposase	Q9MBM9	Staphylococcus_prophage	1.0e-44	36.9
WP_041205601.1\|3249083_3250034_-\|transposase	IS1595-like element ISAeca5 family transposase	NA	NA	NA	NA
WP_005332567.1\|3250086_3252051_-	DUF2235 domain-containing protein	NA	NA	NA	NA
WP_041206280.1\|3252050_3252851_-	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_081805761.1\|3252847_3255619_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.3e-31	26.5
WP_005332563.1\|3256084_3256603_-	type VI secretion system effector Hcp1	NA	NA	NA	NA
WP_041206281.1\|3256834_3257602_-	LuxR family transcriptional regulator	A0A1I9KF49	Aeromonas_phage	2.8e-37	36.1
WP_005332561.1\|3258177_3259668_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	2.5e-215	79.6
WP_005332560.1\|3260218_3260452_-	thioredoxin family protein	NA	NA	NA	NA
WP_005332559.1\|3260465_3261467_-	permease	NA	NA	NA	NA
WP_041206283.1\|3261581_3263018_-	glutathione synthase	NA	NA	NA	NA
WP_005332545.1\|3263131_3263647_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_005332542.1\|3263676_3264108_-	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	2.2e-47	66.9
WP_041206284.1\|3264104_3265181_-	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_005332538.1\|3265180_3266422_-	organoarsenical effux MFS transporter ArsJ	NA	NA	NA	NA
WP_005332536.1\|3266429_3267446_-	ArsJ-associated glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_005332534.1\|3267456_3267972_-	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_005332532.1\|3268029_3268398_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_041206285.1\|3269002_3269752_+	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_005332530.1\|3269824_3270838_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	5.7e-86	48.0
WP_005332528.1\|3270923_3271931_-	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_041206287.1\|3272024_3273674_-	hydroxylamine reductase	NA	NA	NA	NA
WP_041206289.1\|3273921_3274389_-	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	1.6e-19	35.3
WP_005332524.1\|3274520_3275063_-	DUF3833 domain-containing protein	NA	NA	NA	NA
WP_041206291.1\|3275077_3275620_-	chalcone isomerase family protein	NA	NA	NA	NA
WP_005332522.1\|3275576_3275795_-	TIGR02450 family Trp-rich protein	NA	NA	NA	NA
WP_005332520.1\|3275791_3276271_-	DUF2878 domain-containing protein	NA	NA	NA	NA
WP_041206292.1\|3276273_3277530_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_005332515.1\|3277639_3278386_-	DUF1365 domain-containing protein	NA	NA	NA	NA
WP_005332514.1\|3278382_3279642_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_005332513.1\|3279638_3280373_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_005332512.1\|3280369_3280798_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_005332511.1\|3280799_3282224_-	deoxyribodipyrimidine photo-lyase	A0A1V0CPD8	Kaumoebavirus	1.2e-49	30.9
WP_041206293.1\|3282220_3283108_-	MerR family transcriptional regulator	Q9EYF2	Enterobacteria_phage	1.4e-16	37.8
WP_005332508.1\|3283306_3284251_-	DUF1722 domain-containing protein	NA	NA	NA	NA
WP_005332506.1\|3284424_3285054_-	autotransporter	NA	NA	NA	NA
WP_041206294.1\|3285236_3285791_-	DUF3157 family protein	NA	NA	NA	NA
WP_005332502.1\|3285886_3286717_-	hypothetical protein	NA	NA	NA	NA
WP_005332499.1\|3286865_3287465_-	HAD family phosphatase	NA	NA	NA	NA
WP_025328009.1\|3287790_3288963_+	prephenate dehydratase	NA	NA	NA	NA
WP_041206295.1\|3289118_3289544_-	LPP20 family lipoprotein	NA	NA	NA	NA
WP_005332494.1\|3289564_3290185_-	hypothetical protein	NA	NA	NA	NA
WP_005332493.1\|3290469_3291624_+	flagellar assembly protein T N-terminal domain-containing protein	NA	NA	NA	NA
WP_005332492.1\|3291877_3292798_-	carbohydrate porin	NA	NA	NA	NA
WP_019706001.1\|3293968_3294916_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_010676219.1\|3295200_3296298_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_011191341.1\|3296474_3297749_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_25

3391559 : 3460507

Vibrio_phage(14.29%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005323562.1\|3391559_3392477_-\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-101	59.5
WP_041206321.1\|3393869_3394844_+	ChaN family lipoprotein	NA	NA	NA	NA
WP_005329152.1\|3394869_3395424_+	cysteine hydrolase	NA	NA	NA	NA
WP_025328092.1\|3395463_3395868_+	hypothetical protein	NA	NA	NA	NA
WP_005329149.1\|3395938_3396496_-	heme utilization protein HutZ	NA	NA	NA	NA
WP_005329147.1\|3396492_3397005_-	heme utilization cystosolic carrier protein HutX	NA	NA	NA	NA
WP_005329145.1\|3397173_3398013_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005329142.1\|3398009_3399041_+	iron ABC transporter permease	NA	NA	NA	NA
WP_041206322.1\|3399056_3399857_+	heme ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	2.3e-13	26.7
WP_005329125.1\|3400106_3400715_-	YitT family protein	NA	NA	NA	NA
WP_041206324.1\|3401018_3402380_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	3.3e-81	38.0
WP_005329119.1\|3402376_3403375_+	NAD-dependent epimerase	A0A1V0SKV4	Klosneuvirus	5.7e-30	30.8
WP_041206327.1\|3403458_3405147_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
WP_041206328.1\|3405136_3405502_-	lipid-A-disaccharide synthase N-terminal domain-containing protein	NA	NA	NA	NA
WP_005329116.1\|3405590_3406331_-	glycosyltransferase family 2 protein	V9QJB1	Oenococcus_phage	1.5e-06	26.5
WP_041206330.1\|3406682_3407528_+	lytic transglycosylase domain-containing protein	A0A0H3V0Q1	Geobacillus_virus	9.1e-21	44.1
WP_005329110.1\|3407859_3409527_+	energy-dependent translational throttle protein EttA	A0A2K9L3Z8	Tupanvirus	3.9e-39	28.0
WP_005329107.1\|3409795_3410131_+	hypothetical protein	NA	NA	NA	NA
WP_041206332.1\|3410392_3411748_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	7.9e-67	38.0
WP_049832204.1\|3411793_3413131_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005327208.1\|3413256_3414075_-	co-chaperone DjlA	NA	NA	NA	NA
WP_041206335.1\|3414094_3414763_-	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_041206336.1\|3414759_3415788_-	phosphotransferase	NA	NA	NA	NA
WP_005327225.1\|3415962_3418395_+	LPS assembly protein LptD	NA	NA	NA	NA
WP_005327228.1\|3418425_3419718_+	peptidylprolyl isomerase SurA	NA	NA	NA	NA
WP_041207076.1\|3419732_3420728_+	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_041206338.1\|3420717_3421545_+	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_041206340.1\|3421549_3421912_+	Co2+/Mg2+ efflux protein ApaG	NA	NA	NA	NA
WP_005327236.1\|3421918_3422740_+	symmetrical bis(5'-nucleosyl)-tetraphosphatase	A0A2R4ALP3	Aeromonas_phage	6.2e-06	42.5
WP_005327237.1\|3422806_3423292_-	2TM domain-containing protein	NA	NA	NA	NA
WP_041206342.1\|3423462_3424452_-	luciferase-like monooxygenase	NA	NA	NA	NA
WP_041206344.1\|3424683_3427569_+	HD domain-containing protein	NA	NA	NA	NA
WP_041206346.1\|3427638_3429009_-	YjiH family protein	NA	NA	NA	NA
WP_005327243.1\|3429377_3430583_-	Obg family GTPase CgtA	NA	NA	NA	NA
WP_005911261.1\|3430772_3431030_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_005304210.1\|3431047_3431359_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_005327245.1\|3431601_3432573_+	octaprenyl diphosphate synthase	A0A1V0SE37	Indivirus	3.3e-06	23.3
WP_005327246.1\|3432665_3432854_-	DUF2065 domain-containing protein	NA	NA	NA	NA
WP_041206348.1\|3432939_3433824_-\|protease	protease modulator HflC	NA	NA	NA	NA
WP_041206349.1\|3433827_3434976_-\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA
WP_005327255.1\|3435058_3436345_-	GTPase HflX	NA	NA	NA	NA
WP_011704864.1\|3436408_3436672_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_081805770.1\|3436744_3437677_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_005327259.1\|3437758_3439630_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	4.6e-57	30.6
WP_041206350.1\|3439810_3441346_-	N-acetylmuramoyl-L-alanine amidase	A0A059WLJ5	Vibrio_phage	6.1e-15	30.4
WP_041206351.1\|3441336_3441810_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_041206352.1\|3441827_3443330_-	bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase	NA	NA	NA	NA
WP_005327306.1\|3443462_3444617_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_005327307.1\|3444700_3445444_+	ROK family protein	NA	NA	NA	NA
WP_005327308.1\|3445498_3445954_-	hypothetical protein	NA	NA	NA	NA
WP_041206353.1\|3446436_3447480_+	methionine ABC transporter ATP-binding protein MetN	G9BWD6	Planktothrix_phage	4.0e-34	36.9
WP_005327310.1\|3447538_3448192_+	ABC transporter permease	NA	NA	NA	NA
WP_005327312.1\|3448218_3449019_+	methionine ABC transporter substrate-binding lipoprotein MetQ	NA	NA	NA	NA
WP_041205253.1\|3449136_3450474_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005331636.1\|3450559_3451060_+	transcription/translation regulatory transformer protein RfaH	NA	NA	NA	NA
WP_041206354.1\|3451217_3453194_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.5e-13	62.4
WP_041206355.1\|3453231_3454443_-	EAL domain-containing response regulator	NA	NA	NA	NA
WP_004576012.1\|3459088_3460507_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA

DBSCAN-SWA_26

3631368 : 3710536

Klosneuvirus(18.75%)

integrase,transposase,tRNA

attL 3644864:3644880|attR 3686242:3686258

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041207088.1\|3631368_3632007_+\|transposase	transposase	NA	NA	NA	NA
WP_005332231.1\|3632838_3634176_+	DUF3300 domain-containing protein	NA	NA	NA	NA
WP_158319069.1\|3634259_3635117_+	DUF2950 family protein	NA	NA	NA	NA
WP_005332225.1\|3635471_3636185_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_005332223.1\|3636262_3637471_-	phosphopentomutase	NA	NA	NA	NA
WP_005332220.1\|3637485_3638817_-	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	8.9e-79	40.3
WP_005332219.1\|3638889_3639663_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_005332215.1\|3640053_3640224_-	DUF1427 family protein	R4TMJ4	Halovirus	6.3e-06	60.0
WP_041206433.1\|3640347_3641622_-	NupC/NupG family nucleoside CNT transporter	NA	NA	NA	NA
WP_005332213.1\|3641831_3642623_-	TatD family hydrolase	NA	NA	NA	NA
WP_005332212.1\|3642663_3643281_+	type IVa pilus pseudopilin TppF	NA	NA	NA	NA
WP_081805784.1\|3643249_3643432_-	DUF5363 family protein	NA	NA	NA	NA
WP_193354205.1\|3643514_3644024_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_041206437.1\|3644146_3645499_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	1.6e-91	41.8
3644864:3644880	attL	NA	NA	NA	NA
WP_005332207.1\|3645732_3647160_-	ammonium transporter	NA	NA	NA	NA
WP_041206439.1\|3648457_3649747_-	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
WP_148304713.1\|3649743_3651456_-	type I secretion system permease/ATPase	W5SAS9	Pithovirus	8.9e-15	28.3
WP_005332198.1\|3651456_3652695_-	glycosyltransferase	NA	NA	NA	NA
WP_041206441.1\|3652819_3663502_-	DUF4347 domain-containing protein	NA	NA	NA	NA
WP_158319070.1\|3663689_3664010_+	hypothetical protein	NA	NA	NA	NA
WP_041206442.1\|3664148_3664451_-	hypothetical protein	NA	NA	NA	NA
WP_005324741.1\|3665256_3665430_-	hypothetical protein	NA	NA	NA	NA
WP_041206444.1\|3665729_3666164_-	hypothetical protein	NA	NA	NA	NA
WP_011191341.1\|3666764_3668039_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_081805785.1\|3670115_3672584_-	DUF927 domain-containing protein	A0A1B0VP75	Pseudomonas_phage	1.3e-70	34.8
WP_004576012.1\|3672671_3674090_-\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_041206449.1\|3675067_3675313_-	hypothetical protein	NA	NA	NA	NA
WP_148304714.1\|3675536_3676256_-	hypothetical protein	NA	NA	NA	NA
WP_041206452.1\|3676303_3677323_-\|integrase	site-specific integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	5.0e-13	28.6
WP_005332441.1\|3677663_3678182_+	RDD family protein	NA	NA	NA	NA
WP_041206454.1\|3678265_3679336_-	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_005332438.1\|3679361_3680474_-	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_041206455.1\|3680646_3682158_+	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	1.4e-48	37.6
WP_041206456.1\|3682314_3682770_+	DNA polymerase III subunit chi	NA	NA	NA	NA
WP_005332435.1\|3682835_3685688_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.1e-137	36.0
WP_005332434.1\|3685931_3687224_+	HlyC/CorC family transporter	NA	NA	NA	NA
3686242:3686258	attR	NA	NA	NA	NA
WP_005332433.1\|3687242_3687908_+	DedA family protein	NA	NA	NA	NA
WP_041206457.1\|3688044_3688872_+	D-alanyl-D-alanine endopeptidase	NA	NA	NA	NA
WP_005315760.1\|3690110_3690299_-	carbon storage regulator CsrA	A0A2I7RT00	Vibrio_phage	5.0e-12	66.7
WP_005332431.1\|3690392_3691640_-	aspartate kinase	NA	NA	NA	NA
WP_041206458.1\|3691656_3694281_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	4.0e-75	37.7
WP_041205242.1\|3694402_3695740_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005324576.1\|3696000_3696501_-	regulatory protein RecX	NA	NA	NA	NA
WP_005324574.1\|3696541_3697603_-	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	2.5e-116	64.4
WP_041207091.1\|3697683_3698175_-	nicotinamide-nucleotide amidase	B5TK85	Pseudomonas_phage	2.0e-28	49.0
WP_041206459.1\|3698420_3698828_+	Spy/CpxP family protein refolding chaperone	NA	NA	NA	NA
WP_005324564.1\|3699091_3701662_+	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	7.6e-34	24.0
WP_041206460.1\|3701732_3703331_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	1.2e-26	25.4
WP_025325616.1\|3703340_3703868_-	hypothetical protein	NA	NA	NA	NA
WP_041207092.1\|3704032_3704512_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_005324553.1\|3704577_3705159_-	YjaG family protein	NA	NA	NA	NA
WP_005324551.1\|3705320_3706265_+	D-2-hydroxyacid dehydrogenase	NA	NA	NA	NA
WP_041206461.1\|3706331_3707669_-	murein DD-endopeptidase MepM	I3PV79	Clostridium_phage	2.0e-17	45.5
WP_019706001.1\|3709588_3710536_-\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7

DBSCAN-SWA_27

3731487 : 3776993

Bacillus_virus(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205051.1\|3731487_3732825_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_081805790.1\|3733032_3733314_+	hypothetical protein	NA	NA	NA	NA
WP_041206475.1\|3733375_3733750_+	hypothetical protein	NA	NA	NA	NA
WP_005330466.1\|3733859_3734072_-	hypothetical protein	NA	NA	NA	NA
WP_005330464.1\|3734361_3734736_+	hypothetical protein	NA	NA	NA	NA
WP_099993964.1\|3735404_3736421_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_041206480.1\|3736720_3739009_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	7.3e-89	36.5
WP_005327124.1\|3739167_3741057_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	1.0e-91	36.4
WP_005327126.1\|3741196_3741592_-	GFA family protein	NA	NA	NA	NA
WP_041206482.1\|3741630_3742254_-	NUDIX hydrolase	NA	NA	NA	NA
WP_041206483.1\|3742256_3742844_-	esterase	NA	NA	NA	NA
WP_041206484.1\|3742857_3743676_-	3',5'-cyclic-AMP phosphodiesterase	NA	NA	NA	NA
WP_041206485.1\|3743704_3744151_-	DUF1249 domain-containing protein	NA	NA	NA	NA
WP_025325572.1\|3744235_3744877_-	ADP-ribose diphosphatase	A0A1S6L1P8	Vibrio_phage	1.1e-23	35.6
WP_041206486.1\|3745182_3746508_+	outer membrane channel protein TolC	NA	NA	NA	NA
WP_005327142.1\|3746607_3748035_-	bifunctional D-glycero-beta-D-manno-heptose-7-phosphate kinase/D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase HldE	A0A0K0KVL9	Prochlorococcus_phage	2.7e-17	38.4
WP_041206487.1\|3748289_3749213_+	LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase	A0A1W6JP29	Morganella_phage	3.3e-56	40.5
WP_158319071.1\|3749399_3749549_+	hypothetical protein	NA	NA	NA	NA
WP_099368947.1\|3749583_3750670_+\|transposase	IS3-like element ISKpn10 family transposase	NA	NA	NA	NA
WP_005324976.1\|3751991_3753971_-	bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase	NA	NA	NA	NA
WP_005324974.1\|3754098_3754719_-	amino acid transporter	NA	NA	NA	NA
WP_005324972.1\|3754983_3755766_-	LuxR family transcriptional regulator	A0A1I9KF49	Aeromonas_phage	1.4e-55	47.8
WP_041206489.1\|3755830_3756457_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_041206490.1\|3756700_3757600_+	LysR family transcriptional regulator ArgP	NA	NA	NA	NA
WP_005324966.1\|3757686_3759723_+	exoribonuclease II	Q0GXV6	Lactococcus_phage	3.6e-31	29.1
WP_041205051.1\|3759843_3761181_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_041206012.1\|3761638_3763201_+\|transposase	IS21-like element ISAs28 family transposase	K4I413	Acidithiobacillus_phage	3.3e-125	46.2
WP_021141277.1\|3763224_3763980_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.4e-52	45.4
WP_041206491.1\|3764588_3766517_+	PTS mannitol transporter subunit IICBA	NA	NA	NA	NA
WP_041206492.1\|3766554_3767700_+	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_005332927.1\|3767816_3768338_+	mannitol operon repressor	NA	NA	NA	NA
WP_005332928.1\|3768470_3770258_+	sodium:proton antiporter	NA	NA	NA	NA
WP_005332929.1\|3770347_3770596_+	hypothetical protein	NA	NA	NA	NA
WP_041206496.1\|3770635_3771154_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_041206497.1\|3771163_3772129_-	zinc transporter ZntB	NA	NA	NA	NA
WP_005332933.1\|3772269_3772722_+	YaiI/YqxD family protein	NA	NA	NA	NA
WP_005332935.1\|3772838_3773108_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_041206498.1\|3773156_3773717_+	cytochrome b/b6 domain-containing protein	NA	NA	NA	NA
WP_041206499.1\|3774112_3775318_-	nucleoside permease	NA	NA	NA	NA
WP_021141311.1\|3775856_3776993_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA

DBSCAN-SWA_28

3781536 : 3845212

Bacillus_thuringiensis_phage(23.08%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041205051.1\|3781536_3782874_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_041207095.1\|3783001_3783907_-	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_041206502.1\|3784114_3785446_+	isochorismate synthase	NA	NA	NA	NA
WP_005329415.1\|3785479_3787213_+	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	NA	NA	NA	NA
WP_041206503.1\|3787202_3787970_+	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	NA	NA	NA	NA
WP_005329409.1\|3788056_3788917_+	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
WP_005329406.1\|3788916_3789846_+	o-succinylbenzoate synthase	NA	NA	NA	NA
WP_041206505.1\|3789856_3791266_+	AMP-binding protein	A0A1V0SBX8	Catovirus	3.3e-07	35.7
WP_041206506.1\|3791443_3794188_+	collagenase	NA	NA	NA	NA
WP_148304715.1\|3794374_3795433_+	YdcF family protein	Q56AS0	Bacillus_thuringiensis_phage	7.2e-07	81.2
WP_005329392.1\|3795499_3796114_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	3.6e-99	86.6
WP_041207097.1\|3796137_3796563_-	hypothetical protein	Q56AR5	Bacillus_thuringiensis_phage	2.6e-24	70.1
WP_041206507.1\|3796841_3797753_+	triacylglycerol lipase	NA	NA	NA	NA
WP_005329376.1\|3797749_3798508_+	lipase chaperone	NA	NA	NA	NA
WP_005329375.1\|3798544_3799246_-	hypothetical protein	NA	NA	NA	NA
WP_005329373.1\|3799275_3799671_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_005329371.1\|3799721_3801461_-	HTH-type transcriptional regulator SgrR	NA	NA	NA	NA
WP_005329369.1\|3801561_3801738_+	hypothetical protein	NA	NA	NA	NA
WP_041206508.1\|3801893_3803162_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A0B5JD48	Pandoravirus	4.6e-16	26.9
WP_005329365.1\|3803269_3803896_+	glutathione S-transferase family protein	NA	NA	NA	NA
WP_041205242.1\|3803957_3805295_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005328735.1\|3805419_3806595_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_041206510.1\|3806788_3807370_+	hypothetical protein	NA	NA	NA	NA
WP_005328738.1\|3807484_3807922_-	hypothetical protein	NA	NA	NA	NA
WP_041206512.1\|3808122_3808869_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_005328742.1\|3808911_3809157_-	DUF3624 family protein	NA	NA	NA	NA
WP_041206513.1\|3809398_3809857_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005328745.1\|3810043_3811492_+	RimK family alpha-L-glutamate ligase	NA	NA	NA	NA
WP_041206514.1\|3811538_3813155_-	glycosidase	NA	NA	NA	NA
WP_005328751.1\|3813279_3813552_-	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_041206516.1\|3813812_3815777_+	LTA synthase family protein	NA	NA	NA	NA
WP_025328549.1\|3815955_3816852_-	methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_005328754.1\|3817179_3817974_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005328755.1\|3818036_3819482_-	carbohydrate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_041206517.1\|3819490_3821467_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.8e-20	26.4
WP_041206519.1\|3821667_3822279_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_005328758.1\|3822373_3823291_-\|transposase	IS5-like element ISAeme7 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-93	56.5
WP_005328767.1\|3823986_3826815_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	56.4
WP_139750669.1\|3826909_3827548_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005328769.1\|3828063_3828639_+	single-stranded DNA-binding protein	R9TR60	Vibrio_phage	1.8e-52	57.4
WP_005328770.1\|3828795_3829566_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_025328558.1\|3830077_3830362_+	DUF3811 domain-containing protein	NA	NA	NA	NA
WP_025328559.1\|3830755_3830968_+	RNA chaperone/antiterminator CspA	A0A1W6JNX5	Morganella_phage	2.4e-23	77.1
WP_005328779.1\|3831205_3832591_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_041207099.1\|3832598_3833321_-	response regulator	W8CYM9	Bacillus_phage	3.1e-33	36.7
WP_005328782.1\|3833521_3833878_+	hypothetical protein	NA	NA	NA	NA
WP_005328788.1\|3836157_3836571_-	hypothetical protein	NA	NA	NA	NA
WP_041206522.1\|3836720_3837722_-	diguanylate cyclase	NA	NA	NA	NA
WP_005328794.1\|3838125_3838464_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_005328796.1\|3838489_3839731_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	2.3e-57	36.5
WP_193354207.1\|3839790_3840690_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005328801.1\|3840765_3841164_+	VOC family protein	NA	NA	NA	NA
WP_021141311.1\|3841725_3842862_+\|transposase	ISAs1-like element ISAs12 family transposase	NA	NA	NA	NA
WP_049832211.1\|3842870_3843653_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_099992639.1\|3844195_3845212_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	9.8e-187	99.7

DBSCAN-SWA_29

4624639 : 4761021

108

Escherichia_phage(26.32%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004576012.1\|4624639_4626058_+\|transposase	IS66-like element ISAs21 family transposase	NA	NA	NA	NA
WP_005332393.1\|4626090_4627785_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.4e-33	32.5
WP_005332396.1\|4628198_4629623_+	N-acetylglucosamine-binding protein GbpA	NA	NA	NA	NA
WP_041206759.1\|4629722_4630253_+	cytochrome b/b6 domain-containing protein	NA	NA	NA	NA
WP_005332399.1\|4630342_4631290_-	HTH-type transcriptional regulator Cbl	NA	NA	NA	NA
WP_005332405.1\|4631406_4632474_-	sulfate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-26	33.2
WP_005332418.1\|4632548_4633442_-	sulfate ABC transporter permease subunit CysW	NA	NA	NA	NA
WP_005332419.1\|4633438_4634278_-	sulfate ABC transporter permease subunit CysT	NA	NA	NA	NA
WP_041206760.1\|4634557_4635133_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_005327754.1\|4642283_4643480_+	NnrS family protein	NA	NA	NA	NA
WP_005327753.1\|4643483_4644053_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_005327752.1\|4644168_4645320_+	benzoate/H(+) symporter BenE family transporter	NA	NA	NA	NA
WP_041204874.1\|4645467_4646532_+	DUF3103 family protein	NA	NA	NA	NA
WP_025325515.1\|4646652_4647123_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_005327747.1\|4647883_4648831_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_005327739.1\|4650240_4651404_+	competence protein CinA	NA	NA	NA	NA
WP_005327731.1\|4651411_4651927_-	metal-dependent hydrolase	A0A127AVX7	Bacillus_phage	4.3e-05	40.9
WP_005327730.1\|4652367_4653996_+	DUF342 domain-containing protein	NA	NA	NA	NA
WP_005327726.1\|4654110_4654920_+	sugar-phosphatase	NA	NA	NA	NA
WP_041206762.1\|4655285_4656056_+	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_005327724.1\|4656052_4656457_-	hypothetical protein	NA	NA	NA	NA
WP_041205253.1\|4656532_4657870_-\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_005330947.1\|4657990_4658701_-	HAD-IA family hydrolase	NA	NA	NA	NA
WP_180345053.1\|4658747_4659671_-	tyrosine recombinase XerC	A0A166YH27	Gordonia_phage	2.4e-14	30.6
WP_005330951.1\|4659696_4660377_-	DUF484 family protein	NA	NA	NA	NA
WP_025325502.1\|4660532_4661363_-	diaminopimelate epimerase	NA	NA	NA	NA
WP_005330955.1\|4661459_4662710_-	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_025325500.1\|4662730_4662937_-	lipoprotein	NA	NA	NA	NA
WP_005330957.1\|4663010_4663325_+	iron donor protein CyaY	NA	NA	NA	NA
WP_005330959.1\|4663339_4663993_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_005330961.1\|4664085_4666605_-	class I adenylate cyclase	NA	NA	NA	NA
WP_041207133.1\|4666927_4667857_+	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_041207134.1\|4667903_4668638_+	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_005330965.1\|4668634_4669711_+	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_005330966.1\|4669721_4670885_+	hypothetical protein	NA	NA	NA	NA
WP_041206764.1\|4671007_4672345_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_041206765.1\|4672498_4672750_-	YkgJ family cysteine cluster protein	NA	NA	NA	NA
WP_041206766.1\|4673018_4674029_-	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_041206767.1\|4674247_4675306_+	porin	NA	NA	NA	NA
WP_005328993.1\|4675392_4675872_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005328992.1\|4676150_4678193_+	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_041207136.1\|4678258_4678879_+	PepSY-associated TM helix domain-containing protein	NA	NA	NA	NA
WP_005328990.1\|4679052_4680090_+	acyltransferase family protein	NA	NA	NA	NA
WP_041206768.1\|4680061_4680439_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_041206769.1\|4680560_4680866_+	monooxygenase	NA	NA	NA	NA
WP_193354209.1\|4680885_4681473_-	porin family protein	NA	NA	NA	NA
WP_005328986.1\|4681716_4682355_+	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_005328985.1\|4682429_4683320_-	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	5.8e-18	35.0
WP_005328984.1\|4683596_4684178_-	hypothetical protein	NA	NA	NA	NA
WP_041206771.1\|4684572_4684989_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_049832220.1\|4684988_4685561_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_019706001.1\|4685835_4686783_+\|transposase	IS30-like element ISAs2 family transposase	Q9MBM9	Staphylococcus_prophage	1.4e-41	35.7
WP_099993964.1\|4687003_4688020_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_099993964.1\|4688202_4689219_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_041205297.1\|4689388_4690663_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_081805828.1\|4690701_4692162_+	AAA family ATPase	NA	NA	NA	NA
WP_011191341.1\|4692129_4693404_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_081805829.1\|4694219_4695446_-	2-iminoacetate synthase ThiH	NA	NA	NA	NA
WP_005331001.1\|4695481_4696249_-	thiazole synthase	NA	NA	NA	NA
WP_005331003.1\|4696250_4696451_-	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_005331005.1\|4696453_4697233_-	HesA/MoeB/ThiF family protein	NA	NA	NA	NA
WP_005331007.1\|4697222_4698782_-	thiamine phosphate synthase	NA	NA	NA	NA
WP_180344943.1\|4698778_4700680_-	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_005323562.1\|4701242_4702160_+\|transposase	IS5 family transposase	A0A1V0E8E1	Vibrio_phage	2.6e-101	59.5
WP_011191341.1\|4702332_4703607_+\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_148304725.1\|4703697_4704972_+	aryl-sulfate sulfotransferase	NA	NA	NA	NA
WP_010676219.1\|4705005_4706103_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_148304726.1\|4706068_4706395_+	aryl-sulfate sulfotransferase	NA	NA	NA	NA
WP_041207141.1\|4706483_4707914_+\|transposase	IS4-like element ISAeme22 family transposase	NA	NA	NA	NA
WP_005326718.1\|4708033_4708504_-	hypothetical protein	NA	NA	NA	NA
WP_041206773.1\|4708589_4709006_-	hypothetical protein	NA	NA	NA	NA
WP_005326722.1\|4709096_4709765_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.8e-24	32.9
WP_005326724.1\|4709794_4711024_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_005326726.1\|4711165_4712062_-	30S ribosomal protein S6--L-glutamate ligase	A0A1D7SR78	Cyanophage	8.4e-41	37.1
WP_005326727.1\|4712299_4715995_-	methionine synthase	A0A140XBC7	Dickeya_phage	1.2e-21	80.3
WP_041206775.1\|4716197_4717475_+	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	3.7e-42	40.2
WP_005326732.1\|4717924_4718101_+	hypothetical protein	NA	NA	NA	NA
WP_010674210.1\|4718370_4719984_-\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
WP_099993964.1\|4721518_4722535_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4
WP_010674210.1\|4723074_4724688_+\|transposase	IS1634-like element ISAs25 family transposase	NA	NA	NA	NA
WP_148304727.1\|4725625_4726405_+	hypothetical protein	NA	NA	NA	NA
WP_081805831.1\|4726508_4726694_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_099369027.1\|4726749_4727766_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.1
WP_049832223.1\|4727935_4728643_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	1.7e-49	44.9
WP_041206779.1\|4730706_4731228_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_005331711.1\|4731448_4731712_+	hypothetical protein	NA	NA	NA	NA
WP_041205297.1\|4732210_4733485_-\|transposase	IS4-like element ISApu2 family transposase	NA	NA	NA	NA
WP_005331560.1\|4734093_4734783_-	ATPase	NA	NA	NA	NA
WP_005331561.1\|4734937_4736254_+	MFS transporter	Q6JIH2	Burkholderia_virus	2.4e-36	30.4
WP_005331562.1\|4736385_4737102_+	MarC family NAAT transporter	NA	NA	NA	NA
WP_041206780.1\|4737262_4737466_+	hypothetical protein	NA	NA	NA	NA
WP_049832204.1\|4737637_4738975_+\|transposase	IS4-like element ISAeme15 family transposase	NA	NA	NA	NA
WP_041206781.1\|4739041_4740490_-\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_041206782.1\|4740603_4741410_-	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_005328021.1\|4741531_4745434_-	TIGR02099 family protein	NA	NA	NA	NA
WP_005328020.1\|4745434_4746904_-	ribonuclease G	NA	NA	NA	NA
WP_005328019.1\|4746983_4747571_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_005328018.1\|4747622_4748108_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_041206783.1\|4748107_4748998_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_005328016.1\|4749039_4750080_-	rod shape-determining protein	F2Y0P3	Organic_Lake_phycodnavirus	5.4e-07	22.2
WP_041206784.1\|4750296_4751412_-	hypothetical protein	NA	NA	NA	NA
WP_010676219.1\|4751509_4752607_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_041206785.1\|4753992_4754307_-	MSHA biogenesis protein MshK	NA	NA	NA	NA
WP_041207152.1\|4754299_4754947_-	MSHA biogenesis protein MshJ	NA	NA	NA	NA
WP_041206786.1\|4755689_4756553_-	hypothetical protein	NA	NA	NA	NA
WP_005323609.1\|4756622_4757570_+	pyridoxal-phosphate dependent enzyme	NA	NA	NA	NA
WP_041206788.1\|4757629_4759549_-	RNase E specificity factor CsrD	NA	NA	NA	NA
WP_099993964.1\|4760004_4761021_-\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	2.2e-186	99.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP007567

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection