CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_016787	Corynebacterium diphtheriae HC03, complete sequence	2 crisprs	cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,csa3,cas3,WYL,cas4,DinG	0	16	3	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_016787_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016787_1

42133-44725

TypeI-E

I-E

Consensus_repeat	Method
GTTTTCCCCGCACCAGCGGGGATGAGCC	PILER-CR
GTTTTCCCCGCACCAGCGGGGATGAGCC	CRISPRCasFinder
GTTTTCCCCGCACCAGCGGGGATGAGCC	CRT

42 spacers

cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2

The CRISPR arrays of NC_016787_1

>merge|NC_016787|1|42133-44725|PILER-CR,CRISPRCasFinder,CRT
GTTTTCCCCGCACCAGCGGGGATGAGCCGAAGATTGACCGTCTATCCGAGGCTGTACAAAAGTTTTCCCCGCACCAGCGGGGATGAGCCGTGCTTGTAGGCGGGTGACATCGCCGCGAAACGGTTTTCCCCGCACCAGCGGGGATGAGCCGCACCCGCAAACTTTGACCAGACCGGCACCCTCGTTTTCCCCGCACCAGCGGGGATGAGCCCGGGATTAAATCTAGGCGACTTTGTGCAGGTGGGTTTTCCCCGCACCAGCGGGGATGAGCCCATTGGCTTAACTCTCAACCTATGGAGTTCCTGGTTTTCCCCGCACCAGCGGGGATGAGCCCATTGGCTTAACTCTCAACCTATGGAGTTCCTGGTTTTTTCCCGCACCAGCGGGGATGAGCCCGCCGCGTTTCCAACGACCAATCACCAGCCGCTGTTTTCCCCGCACCAGCGGGGATGAGCCGAATGCCGGAAAAGAAGCCGATTTTGTTTACACGTTTTCCCCGCACCAGCGGGGATGAGCCCAGGGCATTGGAGCTATGCGCTCCATCGGCGCCGTTTTCCCCGCACCAGCGGGGATGAGCCCATGACGGATGAGCAGTACCAAGCCGCTACTGCGTTTTCCCCGCACCAGCGGGGATGAGCCCGACACGGGCTATGACACCCTCTGGGACACAGGTTTTCCCCGCACCAGCGGGGATGAGCCAGCTTCGGAGAGTCCGCAAAATCATGAGTAATAGTTTTCCCCGCACCAGCGGGGATGAGCCCCTGAAGTGCACCGCATGCCCCGTCGCTCACCTGTTTTCCCCGCACCAGCGGGGATGAGCCACACCCTCGGTGGTAGTGGGTTCCCCACAGCACGTTTTCCCCGCACCAGCGGGGATGAGCCCACCCTCACGGCGGTGACGGGTGCGACTGAGAAGTTTTCCCCGCACCAGCGGGGATGAGCCGCAGCAGATCATGCTATCCATGCTGCGTGACCTGTTTTCCCCGCACCAGCGGGGATGAGCCCGATGACCGCGGCCTTGTGCAGGTCAAGATTAGGTTTTCCCCGCACCAGCGGGGATGAGCCGCATTCGAGGCTGCCGCCTAAGCCCCCAGCATGGTTTTCCCCGCACCAGCGGGGATGAGCCGCACACCGAAACCGCTTATTTATCGGGTAAGAAGTTTTCCCCGCACCAGCGGGGATGAGCCCACGGGATTTGCGCGCCGTTCAGGAGCTTCTAGGTTTTTCCCGCACCAGCGGGGATGAGCCCCCGCTGCGATTCGACCCCGCTGCCTTGCTTGCGTTTTCCCCGCACCAGCGGGGATGAGCCCCAGTTTTCACACCCCGAGTGTTCCACCGAGGTGTTTTCCCCGCACCAGCGGGGATGAGCCTCATCCCGCAGGGTGAGGGAATCAAGCGAGGAAGTTTTCCCCGCACCAGCGGGGATGAGCCGCTGAGCTGGATGCCGTGGAGGGCATCCAGGAGGTTTTCCCCGCACCAGCGGGGATGAGCCCCGCCTTGGGATAGTTTGATGGTGGGGCCACGAGTTTTCCCCGCACCAGCGGGGATGAGCCCTTTCCGCAGGCCGTTACGTTCCACGGCGATAAGTTTTCCCCGCACCAGCGGGGATGAGCCGAATTTGTGGGCGCGGCGTTTCGTGAGGCTCCGGTTTTCCCCGCACCAGCGGGGATGAGCCCCACCACGCCGCACAGGTCGCTGGCTGTATGCGGTTTTCCCCGCACCAGCGGGGATGAGCCGCTTCTGATCTTGCGGCGCTACGCCTACGGGTGGTTTTCCCCGCACCAGCGGGGATGAGCCCCCGCGAGTCTATGTCAAAAGCAAAATTGATGCGTTTTCCCCGCACCAGCGGGGATGAGCCCCGGCAATTACAAATGTGTTAGTTTTTCCAGCTGTTTTCCCCGCACCAGCGGGGATGAGCCGTATGAAACCTTTGCAGACCTGTTCACGACGCAGTTTTCCCCGCACCAGCGGGGATGAGCCCCAGCAACCCGTCCCCAGATCGACCGCTGTCGTGTTTTCCCCGCACCAGCGGGGATGAGCCGAAAACCAATACTCCTACAGCTGGAACGACCAAGTTTTCCCCGCACCAGCGGGGATGAGCCGACCACGGGGGATAGTGCCTCAGCTGCGAGTACTGTTTTCCCCGCACCAGCGGGGGATGAGCCGCGTCTAAATCCGATCCAATTCTTGTGCTTTCCGTTTTCCCCGCACCAGCGGGGGATGAGCCGTGTGACGCCGGTAAAAATGCCGATGGCGATACGTTTTCCCCGCACCAGCGGGGATGAGCCCGACAATACCGAAGGGGTTTAATAACATCGTTGGTTTTCCCCGCACCAGCGGGGATGAGCCCAAGACGCCCCACATCATCTGTTTTTCCGAGGCGTTTTCCCCGCACCAGCGGGGATGAGCCCATTGTGCACAATTCTTGAACTAATGGAGGAATGTTTTCCCCGCACCAGCGGGGATGAGCCGAAAACCAATACTCCTACAGCTGGAACGACCAAGTTTTCCCCGCACTAGCGGGGATGAGCTGTTGTTAACGGATCCACGAGACACACCCAGTATGTTTTCCCCGCACTAGCGGGGATGAGCC

>NC_016787|1|1|42133-44725|PILER-CR
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAGATTGACCGTCTATCCGAGGCTGTACAAAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GTGCTTGTAGGCGGGTGACATCGCCGCGAAACG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCACCCGCAAACTTTGACCAGACCGGCACCCTC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGGGATTAAATCTAGGCGACTTTGTGCAGGTGG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATTGGCTTAACTCTCAACCTATGGAGTTCCTG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATTGGCTTAACTCTCAACCTATGGAGTTCCTGG
TTTTTTCCCGCACCAGCGGGGATGAGCC	CGCCGCGTTTCCAACGACCAATCACCAGCCGCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAATGCCGGAAAAGAAGCCGATTTTGTTTACAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CAGGGCATTGGAGCTATGCGCTCCATCGGCGCC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATGACGGATGAGCAGTACCAAGCCGCTACTGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGACACGGGCTATGACACCCTCTGGGACACAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	AGCTTCGGAGAGTCCGCAAAATCATGAGTAATA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCTGAAGTGCACCGCATGCCCCGTCGCTCACCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	ACACCCTCGGTGGTAGTGGGTTCCCCACAGCAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CACCCTCACGGCGGTGACGGGTGCGACTGAGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCAGCAGATCATGCTATCCATGCTGCGTGACCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGATGACCGCGGCCTTGTGCAGGTCAAGATTAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCATTCGAGGCTGCCGCCTAAGCCCCCAGCATG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCACACCGAAACCGCTTATTTATCGGGTAAGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CACGGGATTTGCGCGCCGTTCAGGAGCTTCTAG
GTTTTTCCCGCACCAGCGGGGATGAGCC	CCCGCTGCGATTCGACCCCGCTGCCTTGCTTGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCAGTTTTCACACCCCGAGTGTTCCACCGAGGT
GTTTTCCCCGCACCAGCGGGGATGAGCC	TCATCCCGCAGGGTGAGGGAATCAAGCGAGGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCTGAGCTGGATGCCGTGGAGGGCATCCAGGAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCGCCTTGGGATAGTTTGATGGTGGGGCCACGA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTTTCCGCAGGCCGTTACGTTCCACGGCGATAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAATTTGTGGGCGCGGCGTTTCGTGAGGCTCCG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCACCACGCCGCACAGGTCGCTGGCTGTATGCG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCTTCTGATCTTGCGGCGCTACGCCTACGGGTG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCCGCGAGTCTATGTCAAAAGCAAAATTGATGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCGGCAATTACAAATGTGTTAGTTTTTCCAGCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GTATGAAACCTTTGCAGACCTGTTCACGACGCA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCAGCAACCCGTCCCCAGATCGACCGCTGTCGT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAAACCAATACTCCTACAGCTGGAACGACCAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GACCACGGGGGATAGTGCCTCAGCTGCGAGTACT
GTTTTCCCCGCACCAGCGGGGGATGAGC	CGCGTCTAAATCCGATCCAATTCTTGTGCTTTCCGTTTTCC
CCGCACCAGCGGGGGATGAGCCGTGTGA	CGCCGGTAAAAATGCCGATGGCGATACGTTTTCCCCGCACC
AGCGGGGATGAGCCCGACAATACCGAAG	GGGTTTAATAACATCGTTGGTTTTCCCCGCACC
AGCGGGGATGAGCCCAAGACGCCCCACA	TCATCTGTTTTTCCGAGGCGTTTTCCCCGCACC
AGCGGGGATGAGCCCATTGTGCACAATT	CTTGAACTAATGGAGGAATGTTTTCCCCGCACC
AGCGGGGATGAGCCGAAAACCAATACTC	CTACAGCTGGAACGACCAAGTTTTCCCCGCACT
AGCGGGGATGAGCTGTTGTTAACGGATC	CACGAGACACACCCAGTATGTTTTCCCCGCACT
AGCGGGGATGAGCC

>NC_016787|1|1|42133-44725|CRISPRCasFinder
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAGATTGACCGTCTATCCGAGGCTGTACAAAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GTGCTTGTAGGCGGGTGACATCGCCGCGAAACG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCACCCGCAAACTTTGACCAGACCGGCACCCTC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGGGATTAAATCTAGGCGACTTTGTGCAGGTGG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATTGGCTTAACTCTCAACCTATGGAGTTCCTG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATTGGCTTAACTCTCAACCTATGGAGTTCCTGG
TTTTTTCCCGCACCAGCGGGGATGAGCC	CGCCGCGTTTCCAACGACCAATCACCAGCCGCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAATGCCGGAAAAGAAGCCGATTTTGTTTACAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CAGGGCATTGGAGCTATGCGCTCCATCGGCGCC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATGACGGATGAGCAGTACCAAGCCGCTACTGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGACACGGGCTATGACACCCTCTGGGACACAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	AGCTTCGGAGAGTCCGCAAAATCATGAGTAATA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCTGAAGTGCACCGCATGCCCCGTCGCTCACCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	ACACCCTCGGTGGTAGTGGGTTCCCCACAGCAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CACCCTCACGGCGGTGACGGGTGCGACTGAGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCAGCAGATCATGCTATCCATGCTGCGTGACCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGATGACCGCGGCCTTGTGCAGGTCAAGATTAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCATTCGAGGCTGCCGCCTAAGCCCCCAGCATG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCACACCGAAACCGCTTATTTATCGGGTAAGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CACGGGATTTGCGCGCCGTTCAGGAGCTTCTAG
GTTTTTCCCGCACCAGCGGGGATGAGCC	CCCGCTGCGATTCGACCCCGCTGCCTTGCTTGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCAGTTTTCACACCCCGAGTGTTCCACCGAGGT
GTTTTCCCCGCACCAGCGGGGATGAGCC	TCATCCCGCAGGGTGAGGGAATCAAGCGAGGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCTGAGCTGGATGCCGTGGAGGGCATCCAGGAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCGCCTTGGGATAGTTTGATGGTGGGGCCACGA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTTTCCGCAGGCCGTTACGTTCCACGGCGATAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAATTTGTGGGCGCGGCGTTTCGTGAGGCTCCG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCACCACGCCGCACAGGTCGCTGGCTGTATGCG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCTTCTGATCTTGCGGCGCTACGCCTACGGGTG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCCGCGAGTCTATGTCAAAAGCAAAATTGATGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCGGCAATTACAAATGTGTTAGTTTTTCCAGCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GTATGAAACCTTTGCAGACCTGTTCACGACGCA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCAGCAACCCGTCCCCAGATCGACCGCTGTCGT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAAACCAATACTCCTACAGCTGGAACGACCAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GACCACGGGGGATAGTGCCTCAGCTGCGAGTACT
GTTTTCCCCGCACCAGCGGGGGATGAGC	CGCGTCTAAATCCGATCCAATTCTTGTGCTTTCC
GTTTTCCCCGCACCAGCGGGGGATGAGC	CGTGTGACGCCGGTAAAAATGCCGATGGCGATAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGACAATACCGAAGGGGTTTAATAACATCGTTG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CAAGACGCCCCACATCATCTGTTTTTCCGAGGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATTGTGCACAATTCTTGAACTAATGGAGGAAT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAAACCAATACTCCTACAGCTGGAACGACCAA
GTTTTCCCCGCACTAGCGGGGATGAGCT	GTTGTTAACGGATCCACGAGACACACCCAGTAT
GTTTTCCCCGCACTAGCGGGGATGAGCC

>NC_016787|1|1|42133-44725|CRT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAGATTGACCGTCTATCCGAGGCTGTACAAAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GTGCTTGTAGGCGGGTGACATCGCCGCGAAACG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCACCCGCAAACTTTGACCAGACCGGCACCCTC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGGGATTAAATCTAGGCGACTTTGTGCAGGTGG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATTGGCTTAACTCTCAACCTATGGAGTTCCTG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATTGGCTTAACTCTCAACCTATGGAGTTCCTGG
TTTTTTCCCGCACCAGCGGGGATGAGCC	CGCCGCGTTTCCAACGACCAATCACCAGCCGCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAATGCCGGAAAAGAAGCCGATTTTGTTTACAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CAGGGCATTGGAGCTATGCGCTCCATCGGCGCC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATGACGGATGAGCAGTACCAAGCCGCTACTGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGACACGGGCTATGACACCCTCTGGGACACAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	AGCTTCGGAGAGTCCGCAAAATCATGAGTAATA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCTGAAGTGCACCGCATGCCCCGTCGCTCACCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	ACACCCTCGGTGGTAGTGGGTTCCCCACAGCAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CACCCTCACGGCGGTGACGGGTGCGACTGAGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCAGCAGATCATGCTATCCATGCTGCGTGACCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGATGACCGCGGCCTTGTGCAGGTCAAGATTAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCATTCGAGGCTGCCGCCTAAGCCCCCAGCATG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCACACCGAAACCGCTTATTTATCGGGTAAGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CACGGGATTTGCGCGCCGTTCAGGAGCTTCTAG
GTTTTTCCCGCACCAGCGGGGATGAGCC	CCCGCTGCGATTCGACCCCGCTGCCTTGCTTGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCAGTTTTCACACCCCGAGTGTTCCACCGAGGT
GTTTTCCCCGCACCAGCGGGGATGAGCC	TCATCCCGCAGGGTGAGGGAATCAAGCGAGGAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCTGAGCTGGATGCCGTGGAGGGCATCCAGGAG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCGCCTTGGGATAGTTTGATGGTGGGGCCACGA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CTTTCCGCAGGCCGTTACGTTCCACGGCGATAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAATTTGTGGGCGCGGCGTTTCGTGAGGCTCCG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCACCACGCCGCACAGGTCGCTGGCTGTATGCG
GTTTTCCCCGCACCAGCGGGGATGAGCC	GCTTCTGATCTTGCGGCGCTACGCCTACGGGTG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCCGCGAGTCTATGTCAAAAGCAAAATTGATGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCGGCAATTACAAATGTGTTAGTTTTTCCAGCT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GTATGAAACCTTTGCAGACCTGTTCACGACGCA
GTTTTCCCCGCACCAGCGGGGATGAGCC	CCAGCAACCCGTCCCCAGATCGACCGCTGTCGT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAAACCAATACTCCTACAGCTGGAACGACCAA
GTTTTCCCCGCACCAGCGGGGATGAGCC	GACCACGGGGGATAGTGCCTCAGCTGCGAGTACT
GTTTTCCCCGCACCAGCGGGGGATGAGC	CGCGTCTAAATCCGATCCAATTCTTGTGCTTTCC
GTTTTCCCCGCACCAGCGGGGGATGAGC	CGTGTGACGCCGGTAAAAATGCCGATGGCGATAC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CGACAATACCGAAGGGGTTTAATAACATCGTTG
GTTTTCCCCGCACCAGCGGGGATGAGCC	CAAGACGCCCCACATCATCTGTTTTTCCGAGGC
GTTTTCCCCGCACCAGCGGGGATGAGCC	CATTGTGCACAATTCTTGAACTAATGGAGGAAT
GTTTTCCCCGCACCAGCGGGGATGAGCC	GAAAACCAATACTCCTACAGCTGGAACGACCAA
GTTTTCCCCGCACTAGCGGGGATGAGCT	GTTGTTAACGGATCCACGAGACACACCCAGTAT
GTTTTCCCCGCACTAGCGGGGATGAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_016787.1\|WP_014307734.1\|53484_55002_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016787.1\|WP_014307721.1\|32856_33945_+\|glycine-oxidase-ThiO	unknown	unknown	gnl\|CDD\|274092
NC_016787.1\|WP_014307720.1\|28717_29335_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|366759
NC_016787.1\|WP_014302666.1\|49114_49780_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NC_016787.1\|WP_014307733.1\|51466_53488_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	unknown	unknown	gnl\|CDD\|270916
NC_016787.1\|WP_014307731.1\|49783_50719_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NC_016787.1\|WP_010933961.1\|30408_32208_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NC_016787.1\|WP_014307728.1\|46629_47256_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NC_016787.1\|WP_003853351.1\|33928_34129_+\|sulfur-carrier-protein-ThiS	unknown	unknown	gnl\|CDD\|273754
NC_016787.1\|WP_014307730.1\|48408_49113_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|378243
NC_016787.1\|WP_014307729.1\|47270_48404_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NC_016787.1\|WP_014306225.1\|32191_32860_+\|thiamine-phosphate-synthase	unknown	unknown	gnl\|CDD\|234590
NC_016787.1\|WP_014307722.1\|34915_35926_+\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|235528
NC_016787.1\|WP_014307724.1\|36763_37018_+\|hypothetical-protein	unknown	unknown	unknown
NC_016787.1\|WP_003849883.1\|51080_51350_-\|cell-division-protein-CrgA	unknown	unknown	gnl\|CDD\|178907
NC_016787.1\|WP_014307723.1\|35922_36738_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl\|CDD\|237797
NC_016787.1\|WP_014306232.1\|44952_46626_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	cd09729_cas8e_CAS-I-E	gnl\|CDD\|378189
NC_016787.1\|WP_014302658.1\|34130_34916_+\|thiazole-synthase	unknown	unknown	gnl\|CDD\|234687
NC_016787.1\|WP_014307727.1\|39094_41896_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
NC_016787.1\|WP_014307732.1\|50725_51073_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244

Protein	Function_ID	Function_description	E-value
NC_016787.1\|WP_014307734.1\|53484_55002_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.42e-107
NC_016787.1\|WP_014307721.1\|32856_33945_+\|glycine-oxidase-ThiO	gnl\|CDD\|274092	TIGR02352, Glycine_oxidase, glycine oxidase ThiO. This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	1.44278e-129
NC_016787.1\|WP_014307720.1\|28717_29335_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|366759	pfam01694, Rhomboid, Rhomboid family. This family contains integral membrane proteins that are related to Drosophila rhomboid protein. Members of this family are found in bacteria and eukaryotes. Rhomboid promotes the cleavage of the membrane-anchored TGF-alpha-like growth factor Spitz, allowing it to activate the Drosophila EGF receptor. Analysis has shown that Rhomboid-1 is an intramembrane serine protease (EC:3.4.21.105). Parasite-encoded rhomboid enzymes are also important for invasion of host cells by Toxoplasma and the malaria parasite.	2.72806e-26
NC_016787.1\|WP_014302666.1\|49114_49780_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	1.54139e-78
NC_016787.1\|WP_014307733.1\|51466_53488_-\|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.56716e-122
NC_016787.1\|WP_014307731.1\|49783_50719_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.02086e-126
NC_016787.1\|WP_010933961.1\|30408_32208_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NC_016787.1\|WP_014307728.1\|46629_47256_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	1.28152e-31
NC_016787.1\|WP_003853351.1\|33928_34129_+\|sulfur-carrier-protein-ThiS	gnl\|CDD\|273754	TIGR01683, thiamine_biosynthesis_protein_ThiS, thiamine biosynthesis protein ThiS. This model represents ThiS, a small, ubiquitin-like thiamine biosynthesis protein related to MoaD, a molybdenum cofactor biosynthesis protein. Both proteins are involved in sulfur transfer. ThiS has a conserved Gly-Gly C-terminus that is modified, in reactions requiring ThiI, ThiF, IscS, and a sulfur atom from Cys, into the thiocarboxylate that provides the sulfur for thiazole biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	6.74856e-21
NC_016787.1\|WP_014307730.1\|48408_49113_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|378243	pfam09704, Cas_Cas5d, CRISPR-associated protein (Cas_Cas5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum.	3.80295e-41
NC_016787.1\|WP_014306225.1\|32191_32860_+\|thiamine-phosphate-synthase	gnl\|CDD\|234590	PRK00043, thiE, thiamine phosphate synthase.	4.01452e-63
NC_016787.1\|WP_014307722.1\|34915_35926_+\|ThiF-family-adenylyltransferase	gnl\|CDD\|235528	PRK05600, PRK05600, thiamine biosynthesis protein ThiF; Validated.	0
NC_016787.1\|WP_014307729.1\|47270_48404_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	4.24405e-159
NC_016787.1\|WP_003849883.1\|51080_51350_-\|cell-division-protein-CrgA	gnl\|CDD\|178907	PRK00159, PRK00159, putative septation inhibitor protein; Reviewed.	2.52021e-46
NC_016787.1\|WP_014307723.1\|35922_36738_+\|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl\|CDD\|237797	PRK14713, PRK14713, bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase.	2.23643e-109
NC_016787.1\|WP_014306232.1\|44952_46626_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|378189	pfam09481, CRISPR_Cse1, CRISPR-associated protein Cse1 (CRISPR_cse1). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This entry, represented by CT1972 from Chlorobaculum tepidum, is found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse1.	4.80373e-108
NC_016787.1\|WP_014302658.1\|34130_34916_+\|thiazole-synthase	gnl\|CDD\|234687	PRK00208, thiG, thiazole synthase; Reviewed.	1.32018e-147
NC_016787.1\|WP_014307727.1\|39094_41896_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.52333e-92
NC_016787.1\|WP_014307732.1\|50725_51073_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	1.47008e-42

>NC_016787.1|WP_014307727.1|39094_41896_+|CRISPR-associated-helicase/endonuclease-Cas3
MSVVEQADQWRRARSVQSYSLWAKSGSEDLYLRLPQHLIDAACVAEWLWNNWVSDSLKSTLSAAWRLPAEEVGRLYTFYAGTHDVGKATISFQRLVEKTSHGNYLLGPVREAGLSLQWTLNEGEGKKFPHGMASALIIAAWLEKHDIDPSSAARLSFIADAHHGFASDEELYRSHEDTLDYYPPEWLVVHAEILDSMAEITDIGETLEELADQSTPSAPAMQIMTGLVIMADWIASDEKAFPYVCDSSQHDRVVEGMSHVNLPPAWVPTDVPDNVETLFRDTFTWPDSYQVRPVQRAAVAVARAVQDPTLIIIEAPTGEGKTEAGLATSHILGQKTGAQGIFFAAPTMSTANGLFERTKNWAQCTSSRGEVASLYLAHSKNKLSRPFQSLRFTSIGEDDHLEKHGSVVASQWLSGRYRGILSDFVVGTVDQVLMMALQVRFSMLRHVGLAGKIVIIDEVHAYDAYMSQYLYLTLQWLAKYGVSVILMSATLPPQQRARLVNAYASQVCKKADASALNSDAYPLITAVNKKGISVTEVPQENSDTTIKIRRIDDSLPALGGMFSDLLVDGGIALVICNAIRRAQQAYDSLKAIFPDEVELHHAAFIATQRSEKEDALRESLGPHASRGEDRPWRRIVVATQVAEQSLDIDADVLVTDIAPIDLIIQRAGRLHRHERPHSDRPEILGQPQIFIRGINNEEISGEVPEFDGGAAAIYGEKILYATVAYLPDEFHRPSDVPKLVKNVYSDTPCIPENWKEQWEQACVKAKENYEKSVRKAQTFSFPQPHMARTLRDLFKQQHSNSVDKNEESGSAQVRDAEFSIEVVALLKTEYGYHPFGREEEIENGRELTWKEAEALAGNTVRLPAQMTRRDSDFNAVIDSLEAQTPPEWQRSGLLKGQVALFFDERGEARLGRFLVRYTNERGLEVEVCPKEDA
>NC_016787.1|WP_014307724.1|36763_37018_+|hypothetical-protein
MISSLGVRAWHKILGSLALSVQNQGPTVQPNGNAIVDTICRTAELGVTITGAEPVEPHVRAAKKTMNKRRKDILANIRHKINAP
>NC_016787.1|WP_014307723.1|35922_36738_+|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MTPHILTIAGSDPSGGAGIQADLKSIMAAGGYGMAAITALTAQNTCGVTAIHTPPTEFLSEQLRAISDDITIHAIKIGMIGSAEAATAIATWLGQLHHTPIVVLDPVMVATSGSVLGERHYFEPLLHHATVITPNLPELAVLTNNHDPEQTEHAAHSLAEQYDCAVLLKGGHRHGTNDLGNTWITASGPQFHAPSPRIHTTNTHGTGCSLSSALATRLAIEPPEPALHWATTWLNGAIAHGSDLNIGHGNGPVDHSYRLGEYSANCNTIES
>NC_016787.1|WP_014307722.1|34915_35926_+|ThiF-family-adenylyltransferase
MLDELERQRVARQLRLPGFGIEQQERLNKGRVLVIGAGGLGSPALQSLAAAGVGSIRLVDNDTVDVSNIQRQILFGVGDVGRSKVHVAAERLRAIQPRIRIDARTERLTAHNAHDLAEGCDVILDGSDTFATKFLCGDLAEITGIPLVWGSVLQFEGHMGVFTREVGLRDLFPEAPTQGLNCADAGVLGATTAVIANLMATETIKILAGIGTIQPGSITTYNALNSTFRTYTVGRDPLRPAARTLHTWTLPNEYELIDVREPHEIEHTPSGAHITLPQSMWNDTTAIQHALDNITIDDVVVVCASGIRSAAFIEQFAHLNPHLTFHNVPSGINELP
>NC_016787.1|WP_014302658.1|34130_34916_+|thiazole-synthase
MLTIADRSFQSHLIMGTGGASSFDTLEKSLIASGTELTTVAMRRHAAHTGAHGESVFELMQRLNITPLPNTAGCRTARDAILTAQLAREALDTSWIKVEVIADDTTLLPDVLELIDATETLTNDGFTVLAYTSDDPVVAQRLEDAGAAAVMPLGSPIGTGLGILNPHNIELICSRATVPVLLDAGIGTASDATLAMELGCAGVLLASAINRCINPITMATAMKHAVEAGRLAREAGRIPRREHAVASSSFEGLASWADEVL
>NC_016787.1|WP_003853351.1|33928_34129_+|sulfur-carrier-protein-ThiS
MDIYINDTPTAIESPQLTDIISNHCNGIRPGIAVAINQRVIPRSQWDTTTVTAGDHLDILTAVQGG
>NC_016787.1|WP_014307721.1|32856_33945_+|glycine-oxidase-ThiO
MKIAVVGGGIVGLSTAFELSSRGHSVHVFDPNPASGASHFAGGMLAPAAEVQFQQDPLFPLMKRAGKLWPDMVRRVAQRTNLPTGYRTEGTLVVAADRADAEHLKQLRATQEAAGMDVRPITTRQARGLEPALGPRLSAAVHIPNDTQVAPRVFLTALLDALDDCGVEVIKEKITDLEPLYQQFDVVVLAAGLGTQHLSPIPLALRPVRGDILRVQTEPGAVNMVVRGWVNDRPIYIIPRANGEIAIGATSREDERDLPSVEGIYDLLRDAIRVVPGIVDSSLIEANVGVRPGTPDDLPYLGWASDRLIISTGYFRHGILLSALGAHVTACLIDGTDPGIDLTACAPDRHHNERGETHGHLH
>NC_016787.1|WP_014306225.1|32191_32860_+|thiamine-phosphate-synthase
MLPTPRWGRDFDPRCYFVTGTGSVDHIVDVARQAARAGAGLIQVRSKPIAARDLYILGREVARAVAEVNPRTRVLIDDRVDVALALMNNGEHIHGVHVGQDDLPVRHVRALLGDNAIIGLTTGTLELVRASRQVAEVIDYIGAGPFRPTPTKDSGRAPVGLAGYPPLVAESLVPVVAIGDVRPEDAADLAATGVAGVAIVRALMNSQDVATDVKLVLKGFAQ
>NC_016787.1|WP_010933961.1|30408_32208_+|phosphomethylpyrimidine-synthase-ThiC
MSAASANSVTNPSAWENSEIHPKHSYSPIVSGDLEVPETEIQLDDSPTGPNDPVRIYRTRGPECDPTVGLKPLRAQWIDSREDTEEYAGRERNLADDGRSAQRRGAASLEWKGVKPTPRRAKQGKRVTQMHYARQGIITKEMEFVALREHMDPEFVRSEIARGRAIIPNNINHPESEPMIIGRKFLTKINANIGNSAVTSSIEEEVSKLRWATRWGADTVMDLSTGDDIHTTREWIIRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTVIEQCEQGVDYMTIHAGVLLAYIPLTTKRITGIVSRGGSIMAGWCLAHHKESFLYEHFDELCEIFAQYDVAFSLGDGLRPGSVADANDAAQFAELKTIGELARRAWEYDVQVMIEGPGHVPLNMVQENNELEQKWAHDAPFYTLGPLVTDIAPGYDHITSAIGAAHIAMGGTAMLCYVTPKEHLGLPNRDDVKTGVITYKLAAHAADVAKGHPGARAWDDAMSKARFEFRWHDQFALSLDPDTAIAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDMFADKIADLGIPQVGGDAEAGMAAKSEEFVAQGSQLYSEVRDNAAHA
>NC_016787.1|WP_014307720.1|28717_29335_+|rhomboid-family-intramembrane-serine-protease
MVHTEVMNALKRAYGQAPATAVLCALTILIYLLTVVESRSIEHNLSDSWIADHWTLYGPYSHGLGWLRMVGTVFLHSGPTHLALNMFMLFFFGREIEHYLGSGRFTLAYIVSGIGASATVLLMDPLAPTVGASGAVYGLMAIFVAMSYRLRRDLTAPLILIAVNVGYSLLMDGVSLWGHLGGLLTGCVLGIVLVIAQTTRGGKRG
>NC_016787.1|WP_014306232.1|44952_46626_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MASLLEIRWILALDTQGNQISVGIRDIFAGEVQVAYIQGESPAQDYAVMRLLLGIFWRAHSMDIDMDVEPFDFLEWFNKMRRQLARKGKDQVVLDYLDRYADRFELFDAKAPFMQVAGLHVASGEYKHITTIIPEAQDEYFSMRGGKERDSVSIEEAARWLVYVHAFDYSGIKSGAVGDSRVKGGRGYPIGTGWTGMTGGTLVKGEDLLDTLLLNTTLETLNDPEDRPVWERTAYGPGERAVVGENSQPQGPADLATWQSRRIRLIPEGDRVVGVIVCNGDKIPDAGANVLDDPMTPYRFSTNKSKKDHDVYYPRPYDVERTMWKALDALVVAETDGGFSAKEKAPKRPKNLASLAELAVQKANVPAVLNVDLVSVEYGPQASSVATTYASRMSMPVVLLLTEAKHLRGKVREIARATTQSAVALGQFSGNLLDAAGGEYAFQPAITDRVLAELEPRFNDWLERLRDISPEQAIQDNESLTDLEKAWQHTARSVIDQHARILLRGAGPKALAGRIQYRDADDHKGRVVSAAGYYRMLQRKLDEVLPLTVRKQEKEGE
>NC_016787.1|WP_014307728.1|46629_47256_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MAENKDALRAAVGATCHRLQEAYLGDRNSARHHSARATLAELRHGATVDIRKNPLGLEKVLFAMAGDFSDRLVGHGDNPSPSEEAAFVALTLFGVHMQSATSPVHIPQVSFASACGRLHSLGTSDSIKPRVDAMLLASQEQARLVHIRSLVTLLRANNIGFDYGLLARDLRALNDPKKRAGIQLRWGRDFAIGHFRNFNSTTNSTQTA
>NC_016787.1|WP_014307729.1|47270_48404_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MTLVVDIHALQTVPPSLINRDDMGAPKTAIFGGVPRQRVSSQSWKRAVRRFFEDEIDKSTVGLRSRKLPENIVSRAIALGSDLTEDQILDGVRQLFKAAKISLVEPKAPKKGEELPEDAEKYPTTGYLLFLSPYQLDRAAQAVVDKNGEKFTKAEAEDILDTKHSVDMALFGRMLADAPAYNIDASVQVAHAISVHESQPEFDYFTAVDDVVEDAEETGAGMIGTTQMMSSTLYRFATVNVDGLVKNLEDTELAHEAVRMFIRAFAESMPTGKQNSFANNTLPELMYVAVRDTRSVSLVNAFEEPVAAVDGSRRQAAATALAREERDIEEAYGMKPLASFVVALGELGTDFEELAEKVTLTELGEAVIRTLSAQEAK
>NC_016787.1|WP_014307730.1|48408_49113_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MSYSLLLLLKGPLQSWGDESRYNTRATGNTPSKSGVIGLLAAAQGRQRTDSIEDLVALDFAVRVDQSGTLLRDYQTAQPWQKAPKANASLVTRHFLSDAAFVAAIGSEDKELLEGLQGHLRQPTYPLFLGRRSCPAPINLDLGIVDKPVVEALMAHDAWHATSAHQQERSRDVELPIYRDGKPGEHGVPRQDVPLSFAQEHRRYGWRTVVYAGSKSIVNEKGTANDPFFEAVIS
>NC_016787.1|WP_014302666.1|49114_49780_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MATFTKVLINPARRQGRKYLTNPHMLHAAVMHGFPPDCDTSTERILWRLDERGHEHILYVVGPEKPTIDHIVEEAGWDVRPPQSADYDRLLSQLTKGQKWNFELVANPTHTIPVQGGKRGKVVAHSTAAKQLEWLHRKAESMGVSFGTLENSSAQVVGKKTLDFHRSRPNGERGNRVHLVTARFSGQLEVVDADKLRATLIGGVGRAKGYGCGLLTLARGQ
>NC_016787.1|WP_014307731.1|49783_50719_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MSATPSQSPLDRLLLPRMESRLSFLYVERAVINRDGNALTIKDQRGIAHVPATQLAVVLLGPGTKVTYAAMALLGDAGASVVWVGEKGVRYYAHGRPPAKTSRFAEAHARLWSNQRSRLRCARRMYDMRFPGEEISQLSLAQLRGREGARMKKIYAAEAQRTGVVWTRRNYDPQDFESGDPINRALTEGSAALYGIAHAVIVGLGFIPSLGIVHTGTDRAFVYDIADLYKAEISIPAAFEAVAAIPSGDDLNVRARIRDKVVSTRLMQRMVHDLQDLMEIPEEDTYSDVDLMLWSELEVIAAGVNWSTERF
>NC_016787.1|WP_014307732.1|50725_51073_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MIVFVVSAVPAGLRGDLTKWLMEISPGVFVGNPSARIRDLLWERTTELSKDGRALLIYSSNNEQGMEYRTHRHEWEPTDFDGLTLMMRPDNTKPSSYQRRTGWSIARNVRKNRGN
>NC_016787.1|WP_003849883.1|51080_51350_-|cell-division-protein-CrgA
MPKSKINHSSTAYTAGSTANRTPVKINSTGTPLWYKIIMFGLILAGLLWLIVNYLAGQDISFMTELGPWNYGIGFGLFIIGLLMTMGWR
>NC_016787.1|WP_014307733.1|51466_53488_-|Stk1-family-PASTA-domain-containing-Ser/Thr-kinase
MTDIVLADRYRLGDVIGTGGMSEVYEATDVLLGRKVAVKMLRADLARDVNFRERFRREAQNSGKLNHPAIVAVYDTGETPRAGLNTPYIVMELVNGRTLRDIVREDGPLTPSQAAHTLIPVCHALQVSHDAGIIHRDIKPANVMITNTGAVKIMDFGIARALDDATSAMTQTSAVIGTAQYLSPEQARGKLADARSDVYALGCVLYETLTGKPPFEGETPFAVAYQHVQEDPVKPSEYIADLSPTAAINVDAVVLTAMAKHPGDRYQTAQEMCADLERLERNAVTDAARHYVTPTSFATQDPASTTVVPVTQVTELDHAEAGAGIGAGVVPAGAVAGSAAVAGSGGAHAAPRSSNRGLRILAAILTVLVLAVGAGFAIDYFGGGPFSQRSTVSIPKLQNSTQQDAVSQLEKLGLQVNVIEEPNPDIPRGKVIRTNPTDGSNVQRNSTVRLTISSGKEITEVPDLSGKNTADAVKILEAAGLLLDPTVREDSSDTVPKGEIIEVSPAAGSQVSRGSKVSITVSTGVETVRVPVITGMKWDQAEGNLTSLGFKPEVVRVDSVEPAGTVVAVPDEGAEVPKGSSVTVQISNGAMFTVPEITRQTIGDAVRILHDAGWKGNASRLIQAAKVPTVAVTDQNLIASQLPTPGTALRKDAPIEIRLYEFNLAALVPPAQH
>NC_016787.1|WP_014307734.1|53484_55002_-|serine/threonine-protein-kinase
MTQSQSPDPALQALVGSDYALQWVVGNGGMSTVWLADDLRNQREVAIKVLRPEFSDNEEFLSRFRNEALASEHIDSDNVVRTYDYREVTDDMGRTLCFIVMEYVRGESLADMLARKGRLEEDLALDVLEQAAHGLSIIHRMGMVHRDIKPGNLLITQNGQVKITDFGIAKAAAAVPLTRTGMVVGTAQYVSPEQAQGRDVTAATDVYSLGVVGYEMLVGQRPFTGDSSVSVAIAHINQAPPAMPTSVSAPARELIGIALRKDPAHRYADGNELALAVSATRMGQRPPQPKSAPLQHIAPQPAPTESTYALGATAQPTTVIPATGQVPAAPAAAAAYPASTVIPAGTPRQEPEKQSSGWGAGIVVGALAALLLGTAAWAASQGMFDDLFDKTSQSSESSVPPPPVTATVTETPTPQITTVVPEPLPTSSPEPTPSETKRTPEDSHPTSDHQLPSVRPSHNGRPSSQASHAPQAPTQDADQPAESPAPDTLDSLIENLNKLNQGGAQ

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Crispr_ID: NC_016787_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_016787_2

188233-188475

Orphan

Consensus_repeat	Method
TGGTTCAGTCGTTGTTTGTGCTACAGGGGTAGCTGATTTTGCTTCGGCTTCGCTG	PILER-CR

2 spacers

DEDDh

The CRISPR arrays of NC_016787_2

>merge|NC_016787|2|188233-188475|PILER-CR
TCAGTCGTTGTTTGTGCTACAGGGGTGGCCGATTTTACTTCGGCTTCGCTGCCTCGGTATGCCTTGTAGCGGTTAGCTAGAACGTTGTCGCTTGGTTCAGTCGTTGTTTGTGCTACAGGGGTAGCTGATTTTGCTTCGGCTTCGCTGCCTCGGTATGCCTTGTAGCGGTTAGCTAGAACGTTGTCGCTTGGTTCAGTCGTTGTTTGTGCTACAGGGGTAGCTGATTTTGCTTCGGCTTCGCTG

>NC_016787|2|2|188233-188475|PILER-CR
TCAGTCGTTGTTTGTGCTACAGGGGTGGCCGATTTTACTTCGGCTTCGCTGCCTC	GGTATGCCTTGTAGCGGTTAGCTAGAACGTTGTCGCTTGGT
TCAGTCGTTGTTTGTGCTACAGGGGTAGCTGATTTTGCTTCGGCTTCGCTGCCTC	GGTATGCCTTGTAGCGGTTAGCTAGAACGTTGTCGCTTGGT
TCAGTCGTTGTTTGTGCTACAGGGGTAGCTGATTTTGCTTCGGCTTCGCTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_016787.1\|WP_158307780.1\|198609_199098_-\|transposase-family-protein	unknown	unknown	gnl\|CDD\|379669
NC_016787.1\|WP_010934165.1\|200295_201660_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NC_016787.1\|WP_014301258.1\|180671_181643_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176194
NC_016787.1\|WP_014307854.1\|197002_198103_+\|HNH-endonuclease	unknown	unknown	gnl\|CDD\|238038
NC_016787.1\|WP_014301256.1\|178786_180175_+\|GntP-family-permease	unknown	unknown	gnl\|CDD\|225330
NC_016787.1\|WP_014307849.1\|190568_191831_-\|DUF1727-domain-containing-protein	unknown	unknown	gnl\|CDD\|223840
NC_016787.1\|WP_014307846.1\|184903_187033_+\|DNA-polymerase-III-subunit-gamma-and-tau	unknown	unknown	gnl\|CDD\|236090
NC_016787.1\|WP_014307852.1\|193800_195618_-\|2-isopropylmalate-synthase	unknown	unknown	gnl\|CDD\|235154
NC_016787.1\|WP_014307851.1\|192976_193777_-\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
NC_016787.1\|WP_014307844.1\|183078_184338_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|372371
NC_016787.1\|WP_014306349.1\|187429_188086_+\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
NC_016787.1\|WP_003850338.1\|187105_187426_+\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NC_016787.1\|WP_014307848.1\|189814_190567_-\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NC_016787.1\|WP_014307841.1\|177812_178697_+\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|235573
NC_016787.1\|WP_010934164.1\|199582_200299_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NC_016787.1\|WP_014307842.1\|180171_180675_-\|gluconokinase	unknown	unknown	gnl\|CDD\|225804
NC_016787.1\|WP_044035353.1\|181645_182395_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|181225
NC_016787.1\|WP_014307850.1\|191851_192973_-\|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|235529
NC_016787.1\|WP_014307845.1\|184341_184893_+\|suppressor-of-fused-domain-protein	unknown	unknown	gnl\|CDD\|377450
NC_016787.1\|WP_080564354.1\|195798_196797_+\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263

Protein	Function_ID	Function_description	E-value
NC_016787.1\|WP_158307780.1\|198609_199098_-\|transposase-family-protein	gnl\|CDD\|379669	pfam14690, zf-ISL3, zinc-finger of transposase IS204/IS1001/IS1096/IS1165.	0.000469522
NC_016787.1\|WP_010934165.1\|200295_201660_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.18061e-16
NC_016787.1\|WP_014301258.1\|180671_181643_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176194	cd08232, idonate-5-DH, L-idonate 5-dehydrogenase. L-idonate 5-dehydrogenase (L-ido 5-DH ) catalyzes the conversion of L-lodonate to 5-ketogluconate in the metabolism of L-Idonate to 6-P-gluconate. In E. coli, this GntII pathway is a subsidiary pathway to the canonical GntI system, which also phosphorylates and transports gluconate. L-ido 5-DH is found in an operon with a regulator indR, transporter idnT, 5-keto-D-gluconate 5-reductase, and Gnt kinase. L-ido 5-DH is a zinc-dependent alcohol dehydrogenase-like protein. The alcohol dehydrogenase ADH-like family of proteins is a diverse group of proteins related to the first identified member, class I mammalian ADH. This group is also called the medium chain dehydrogenases/reductase family (MDR) which displays a broad range of activities and are distinguished from the smaller short chain dehydrogenases(~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal GroES-like catalytic domain. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	6.24937e-115
NC_016787.1\|WP_014307854.1\|197002_198103_+\|HNH-endonuclease	gnl\|CDD\|238038	cd00085, HNHc, HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and anaredoxins.	1.72885e-07
NC_016787.1\|WP_014301256.1\|178786_180175_+\|GntP-family-permease	gnl\|CDD\|225330	COG2610, GntT, H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism].	4.4285e-119
NC_016787.1\|WP_014307849.1\|190568_191831_-\|DUF1727-domain-containing-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	1.45514e-56
NC_016787.1\|WP_014307846.1\|184903_187033_+\|DNA-polymerase-III-subunit-gamma-and-tau	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0
NC_016787.1\|WP_014307852.1\|193800_195618_-\|2-isopropylmalate-synthase	gnl\|CDD\|235154	PRK03739, PRK03739, 2-isopropylmalate synthase; Validated.	0
NC_016787.1\|WP_014307851.1\|192976_193777_-\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	1.90238e-81
NC_016787.1\|WP_014307844.1\|183078_184338_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|372371	pfam12897, Aminotran_MocR, Alanine-glyoxylate amino-transferase. These proteins catalyze the reversible transfer of an amino group from the amino acid substrate to an acceptor alpha-keto acid. They require pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze this reaction. Trans-amination reactions are of central importance in amino acid metabolism and in links to carbohydrate and fat metabolism. This class of aminotransferases acts as dimers in a head-to-tail configuration.	1.04553e-173
NC_016787.1\|WP_014306349.1\|187429_188086_+\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	4.20157e-107
NC_016787.1\|WP_003850338.1\|187105_187426_+\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	6.29079e-35
NC_016787.1\|WP_014307848.1\|189814_190567_-\|glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	5.15585e-97
NC_016787.1\|WP_014307841.1\|177812_178697_+\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|235573	PRK05710, PRK05710, tRNA glutamyl-Q(34) synthetase GluQRS.	2.91642e-115
NC_016787.1\|WP_010934164.1\|199582_200299_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	3.66425e-144
NC_016787.1\|WP_014307842.1\|180171_180675_-\|gluconokinase	gnl\|CDD\|225804	COG3265, GntK, Gluconate kinase [Carbohydrate transport and metabolism].	2.67434e-84
NC_016787.1\|WP_044035353.1\|181645_182395_-\|SDR-family-oxidoreductase	gnl\|CDD\|181225	PRK08085, PRK08085, gluconate 5-dehydrogenase; Provisional.	8.27448e-99
NC_016787.1\|WP_014307850.1\|191851_192973_-\|DNA-polymerase-III-subunit-epsilon	gnl\|CDD\|235529	PRK05601, PRK05601, DNA polymerase III subunit epsilon; Validated.	0
NC_016787.1\|WP_014307845.1\|184341_184893_+\|suppressor-of-fused-domain-protein	gnl\|CDD\|377450	pfam05076, SUFU, Suppressor of fused protein (SUFU). SUFU, encoding the human orthologue of Drosophila suppressor of fused, appears to have a conserved role in the repression of Hedgehog signaling. SUFU exerts its repressor role by physically interacting with GLI proteins in both the cytoplasm and the nucleus. SUFU has been found to be a tumor-suppressor gene that predisposes individuals to medulloblastoma by modulating the SHH signaling pathway. Genomic contextual analysis of bacterial SUFU versions revealed that they are immunity proteins against diverse nuclease toxins in polymorphic toxin systems.	2.83428e-07
NC_016787.1\|WP_080564354.1\|195798_196797_+\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	1.00431e-98

>NC_016787.1|WP_014306349.1|187429_188086_+|recombination-protein-RecR
MFEGPLQDLIDEFSRLPGVGPKSAQRIAFHLLHVEPADITRLQDALGAIRDGVTFCRICCNISREEVCRICADSSRDRSTICVVEEPKDIQVIERTGEYTGRYHVLGGSLDPLANIGPRELNISQLLQRIGGVLPDRELADSTPEAPLYDASPEVREVILATDPNTEGEATASYLARLLRDFPDLVVSRLASGMPLGGDLEFVDELTLSRALSGRLTL
>NC_016787.1|WP_003850338.1|187105_187426_+|YbaB/EbfC-family-nucleoid-associated-protein
MTQPDMSQILAQAQQMQAKLQEAQREILATTVTGTAGNGLVSIDMQGNGMVSSVTIDPKVVDADDVETLQDLLVGAFAEAHEKLGTLAEQKMGPLSQGFDGLGGMF
>NC_016787.1|WP_014307846.1|184903_187033_+|DNA-polymerase-III-subunit-gamma-and-tau
MALYRKYRPASFAEVVGQEQVTQPLSVALDSGRINHAYLFSGPRGCGKTSSARIMARSLNCVEGPTSTPCGKCNSCISLAPNGPGNLDVTELDAASNRSVDDMRELRDRAMYAPAESRYRIFIIDEAHMITRDGANALLKIVEEPPAHLIFIFATTEPEKILPTIRSRTHHYPFRLLTPQSMRGLLERTVASEHVAVEDSVYPLVIRAGGGSPRDTLSILDQLIAGAGPDGLDYNLARMLLGATDDTLIDTTIDALAGNDNAALFQVVDDAIEAGLDPRRFATDLLDRFRDLMVLQSVPDALTLGLVDAPTDRGDILRDQATHLSAGEAARLAALVNDGLRGLKGATSPRLLLEILCAKMLLPSAPPAATATASAATTPAAAPGPAPTEIPAKYERRSVRLAREAAARKTAEVAAPAPAPKPEPKPEPKPRDGFATIQEKWATISDVIFKANSVAGILLSQATLLGLRDGSTLVIGHNTGALAHRINDPQHAGSIVTAIKQETDLDVTIECVVGTDPKAAGFSEPENKKVWNPDPKPEPKPEPKPEPEPKPEPAPASDNVWGAPAPLGGGQPATPPPVERFSSAKVTAPQPPAAPQPVQEAPKPRWQQAAERGMRKMEERAKRPSFSDGVPLPPEPEEPDVPPDPYGYPADEGMPEPQTPQDTSNYVVDHDEEEEMVREAAQGVGNRDHRDAMTVAVDILSEELGARQL
>NC_016787.1|WP_014307845.1|184341_184893_+|suppressor-of-fused-domain-protein
MNFDETAVWLDGVFPGELTIHSAPAESFRVGTVDLGDDMLATTLDFARVDTGLETGGRDVRSEVFTVAHAGVGAEKFVELLRALGTLLYDASGSLPAQPGQVVPAVGIEPFDDTDITVRHGLFVVPYVWGGEVPQCDEPDRLTVMLQLVMLTQEEFDYAVTYGIPELQSEIARAGIDLLDWSR
>NC_016787.1|WP_014307844.1|183078_184338_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MSLKDYDAARLAQVREEVAAKYAELKAKNLSLDLTRGKPSAEQLDLSNDLLSLPGGDFRTKDGVDCRNYGGLLGIADIRELWAEALGLPADLVVAQDGSSLNIMFDLISWAYTWGNNDSPRPWSAEEKVKWLCPVPGYDRHFTITEHFGFEMINVPMTDEGPDMDVVRELVKDPQVKGMWTVPVFGNPTGVTFSEQTCRELAEMSTAAPDFRIVWDNAYALHTLSDEFPIVHNVIEFAQAAGNPNRFWFMSSTSKITHAGSGVSFFASSKENIEWYASHANVRGIGPNKLNQLAHAQFFGDVAGLKAHMLKHAASLAPKFERVLEILDSRLSEYGVAKWTSPTGGYFISVDVVPGTASRVVELAKEAGIALTGAGSSFPLHNDPNNENIRLAPSLPPVAELEVAMDGFATCVLMAALEV
>NC_016787.1|WP_044035353.1|181645_182395_-|SDR-family-oxidoreductase
MTNFSVVDKLALVTGSTRGLGRVLAQGLIEAGARVVVHGSDAQRAEAAAAELGACGFMACDVRDAVATEAAVSEVIERFGAPDILVNNAGIQRRNPIEVFEDQDWNDIVGVNLSGVFHVTRPVASAMKTAGRGKIVMVGSVQSRLGRATIAPYCATKGGVAMFAQGLAAELSPFNVQVNTLSPGYFDTDMNAALVADEEFSGWVCKRTPAGRWGDPRELVGPLLFLASEASSFVTGQNLAVDGGMTAVV
>NC_016787.1|WP_014301258.1|180671_181643_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MRAAVISGKGLLATADLPTPVVGPDEVLIRVAYVGICGSDLHYYQDGAVGAFEVREPLVPGHEMSGTLADGTAVTVHPATFGQRCAGLEEHPHLWPGGAYLGSASTWPHTQGAMQEFLLVRKDQVRVLPDGVPLRRAALAEPLSVGLHAINVAGGVAGKNVLVSGAGPIGQLAALAALREGAASVTLSDVVDGPLERAHAGLTRVNTRAVRLDDESFDVVLECAGVAVATSDALRVVRRRGVVVQVGMLPNVEVGVNVAPLVAKEVQLRGTFRFRDEVDRAVEMLRDPIFDTVITHEFAVDDVVEAFDTAADSQVSGKVVVAL
>NC_016787.1|WP_014307842.1|180171_180675_-|gluconokinase
MSTAVKVVVMGVSGSGKTTVGTLLAERFGVEYRDGDDLHSQANIEKMASGIPLNDDDRWPWLAQVGEWLAAQLAGGVIGCSALKRSYRDVLRRECPEVVFVHVHGSREVLLERMNHREGHFMPASLLDSQFATLQPLENDEAGHVFDVTDSPAQIADAAARWLSERS
>NC_016787.1|WP_014301256.1|178786_180175_+|GntP-family-permease
MEDWVPTLSAGPLLGIAAAAIALILVLVIVFKLHAFLTLIIVSAATGLAAGIPLEGIVPTMTKGFGSTLASVALLVGLGAMLGRLVETSGGAKSLAETLVARFGEQRAPFALGVASLLMGFPIFFDAGLIVMLPVIFAVARRLNGPVLAYGIPAAGAFSVMHIYLPPHPGPISAAEFYSADIGLVMLLGLIIAIPTWLISGLWLGKTLGRRYPLPVPDILAGGPQATDVKNPATPGLIVSLLLLPMLLIFGNTGMGLATSAGWVDKSSSLVRALQFVGNTPIALLISTLVALYFLGIRRGQPKADLEKLLDGALGPICSVVLITGAGGMFGGVLRTSGIGDALADSMSDLGVPVVLGCWLVAAILRLAQGSATVALTTAAALMAPAVAAGGYSEFQIALMVLASAAGSVFAGHVNDSGFWLVGRLMGMDVATTLRTWTLNQALVGAVGFVFVLVFYGVSFAF
>NC_016787.1|WP_014307841.1|177812_178697_+|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MGTFQGAGRYAPSPSGDLHFGNVRTAVLAWLFARHTGRRFLIRVEDVDTQRSSMESAARQLEDLHALGMDWDAAPTYQHNNFDRYEQALRSLPYYECYCSRKDIQEASRAPHTIPGQYPGTCRNLTEVQREERRQALAKQGRVPALRLRADVPTWHVRDYYAGDVLGDVDDMILRRGGQQPDWAYNLAVVVDDAADGIDQVVRGNDLLTSAPRQAYLAHLLGVPAPTYVHVPLVLNAAGQRLAKRDGAVTMREMPDILPRVAESLGLSAHTLPGMLEEFDPDRLSQQPWIFACL
>NC_016787.1|WP_014307848.1|189814_190567_-|glutamine-amidotransferase
MSELTIGLILPDVLGTYGDDGNALVLRQRARLRGISAEIHPVRLGEAVPEGLDLYCLGGGEDTAQILAAEHLNNDQGLRRAADSGRPILGICAGLQVLGRSFRASGKIVEGVGLIDATTASLAKRTIGELQSTPTAAGFTAELTEPLTGFENHMGATILGPDAQPLGAVTRGVGNTDLHGITTASVSDEQVSYEGAVQGNVVCTYMHGPALARNPQLADLLLAKAMGMTLGELKPLNLEIVDQLRAERLA
>NC_016787.1|WP_014307849.1|190568_191831_-|DUF1727-domain-containing-protein
MSFNLRTRLAIGAAAVATTASRATGRGSGGMIGGLIAEKIDPNIMQSLAKTRPTALVTGTNGKSTTTRMLASAVRAQHTVATNEGGDNMDAGIISALMAGQSASHVVLEVDELHVPSAADRLHPQCLILLNLTRDQLDRVGEINKIERALRDCVTAHPDMTVVANCDDVLVTSVAYDAPNVVWVSAGVGWTGDSVSCPRTGSHIVRQDDHWYATKPLPNGETFQRPTPAWTITPDGILALGHAEPVPLSLALPGNANRGNATQAIAAAVTCFNVPLDDAVRAVETVDDVAGRYSTITLGEHQIHLLLAKNPAGWQEALSMVDRTAEGLVIAVNGQVADGEDLSWLWDVKFEELEELSVKAAGERGTDLSVRLTYASVDHELVRDPLAAIKACPAGRVEVLANYTAFRDLKRAITAATKEA
>NC_016787.1|WP_014307850.1|191851_192973_-|DNA-polymerase-III-subunit-epsilon
MNVSLPTRPPARLFPMTNKDQEERDKARAQRAAEQAAARKAEIEKAPYVALSVQASGIHPSTSRLVTIDAVTFTEQGEEVDHFFAVLNPESNPGPFHLHGLSPGQIKEGKRYSQILKALDRLIDGRTLLVHNAELVWGFIVSESKRAMSNAARTNRSRSRQRNRRRQRVGHIPKPVTIVDTLATARRLGLTFADIRIRNVATQLGLEAPDARASVARAQADTAQLTREDTLLVARMFFVEHAQGVVASTSPEDLRADRFGLQRSNVRVDAMEVPRVWENPGIYTKERGLVQGMEVVVAPEITMDPDRIIQAIVRTELAYNEKITRASSLVVCNKREDLTGKAMHGDRKGIPLMTDEEFLRAVEHVKPGKPAET
>NC_016787.1|WP_014307851.1|192976_193777_-|NADPH-dependent-oxidoreductase
MKAGTKAGTKAGMKASMNETIRTQLNHRTIREFTTEQVSEEIMEQLFAVAGRTATSLGMQSTSIIRVTDPQLRVRLAEIGAQEYVGRSPIYLLFIVDCHRNAGILQELGADPAGAATARNFVQGFTDACLTAQNVCIAAESMGLGVNFLGNVHNDAAAVIELLQLPELTFPVVGMTLGWPNQEPQLKPRMATPLRTMENGYHAPDSWLEALSDYDQEMTTYYDLRDANRRVDSFTRQVLAKNPTAGADSDKRNHTFAIARDQGFNL
>NC_016787.1|WP_014307852.1|193800_195618_-|2-isopropylmalate-synthase
MTSPDTFISAPAAIVTPRGDKAPGQAPWNTQRNSSMAVNRYQPFHVEVENIDLPDRTWPQKRITKAPQWCAVDLRDGNQALIDPMSPERKRRMFNLLVNMGYKEIEVGFPSASQTDFDFVREIIENNIIPDDVTIQVLVQAREHLIRRTFEACEGAKNVIVHFYNSTSILQRDVVFRKDKAAIKKLATDAAELIKSIAVDYPDTNWRWEYSPESYTGTELTYAKEVVDAVVAVMDPTPENPIIINLPSTVEMITPNVYADGIEWMHRNLNRRDSIILSLHPHNDRGTGVAAAELGYLAGADRIEGCLFGNGERTGNVCLVTLGLNMFTQGVDPQIDFSDIDQIRRTVEYCNQLRVPERHPYGGDLVFTAFSGSHQDAVNKGLDAMASRVHPGATHTEVSWDELRGETWEVPYLPIDPKDVGRNYEAVIRVNSQSGKGGVAYIMKTDHGLALPRPMQVEFSSIVQEVTDAEGGEVNSKNMWDIFAREYLDSTSPVEQVSMSVDAAETENDEARIHARLIVNGSETTIEGHGNGPIAAYANALESLGIDVEVQEYEQHARTAGDDAEAAAYVLAEVNGKKFWGVGIAGSITYASLKAITSAVNRALS
>NC_016787.1|WP_080564354.1|195798_196797_+|sugar-binding-transcriptional-regulator
MWNMLWGVSWLGVEWGKNVHMIDARDCLALDAAKLYYVTGLGQAQVAKELGISRPTVSKLLSHARDKGFVTISLNDPREVAGGYVEKLCARYGLVDVRVVQSPAMGRGLTGELGNAGAALLEEVVKDGMTVGVSWGDTMLAVSEHLRTLPLVDVKVVQLKGGHSHTARNTNDMVTLTRFSRALNAEMMMLPLPVILDSKEAKELVVEDRHIASMLNLGAHCDVAVFTVGAVKPESLLLNLGYLSPSEQARLMEHAVGDVCSRFYDAQGEVADPDIDARTVGISLADLKKRPVRVLVAGGLEKAPAIEAALRTGVATHVVIDHATAQRVVEMA
>NC_016787.1|WP_014307854.1|197002_198103_+|HNH-endonuclease
MNTTGETTQPFYSHCDMNDPLCRAERLRIQFDYYRWHSLQPDDNDDVDTYTADIATRIGKTQRYVCDHLDAIYYLTQLPQLHALYQQLWHLDDTRLITITRIISALPTTYYDAIDTHLTRWLTPTQPAQTIPSTRAITRFLRKTITHLGFHLDNTRKPEQYVYIYDAGHGLAGIDALIHAGVAELLETTLRSIKKTHSCDDSTALQLLLEDKTSVVINLYDTGTGITYTPQGTALPQVPEHPVIRVLGDADVAVSTGYRFTEAMRRFIQGRDGVCRFPGCGVPAQWCDIDHVEEYDLGGVTGAVNAQCLCRHHHNVKTSRRVDCEIGAGGVVTWQIGDRRVVTTPEGVLAGQTFRQRREKKIKKAA
>NC_016787.1|WP_158307780.1|198609_199098_-|transposase-family-protein
MQPNPNAIVIEAEPINECPTCRQPRVLRDHVIRSLVDLPIIDHPTRLHVRLPRYRCTNKRCLQKTFHTGLACAPDNPKTTNKVTHWILQHLDLSRCPRRDLQRQALPQRGSRSSVLMSITGRTTDTHDATETSSAPPGFLTLFQKEALTRLRTWLNNHSEVP
>NC_016787.1|WP_010934164.1|199582_200299_+|purine-nucleoside-phosphorylase
MAEKSTPHINPKGVDIAETVLLPGDPLRAKFIADTYLEDVVQFNSVRNMLGFTGTYQGTPVSVMGSGMGMPSIGIYSYELINFFDARNVIRVGSIGAMQKDIDLYEIIVAASASTDSNFLEQYNLPGTYAPTASWTLLRAFMDEADRKGKKVHVGNILSSDVFYNADNTVNERWARMGVLGVEMESAALYSIAAYAGANALGVFTVSDNLFTGARTTAEERESAFTDMMELALPLARA
>NC_016787.1|WP_010934165.1|200295_201660_+|MFS-transporter
MTTHNATLKPTDPKAAVPVLLFSFVFCLIVDNGFKTMTGPMAEGLGIDPNTASLQASLAGVIIGIGAVVYAALADAISIRKLMLIGIGLVVVGSVIGFVFSGSWPLVLAGRLIQTGGLAAAETLYVIYVTKHLAAEDQKTYLGFSTAAFQSGLLVGALTSGAISTYIGWRVMFLVPLILIVAVPFILKTVPEEEASSSHLDVVGLFLIAIFATSVIQYMQAFKLFWLAFMLVSIVIFVWYVRNAKNPVVNPEFFKNGRYVWAILLVLIVYSTQLGYIVLLPFAAKEFHGLDQAQASYLMIPGYICAVLIGIFSGKIGKLMTSRRTIFTALGMIIVALVVGALAIQVHVAVAIASIILFASGFALLYAPLVNTALANILPEKSGVAIGFYNLTINIGVPLGIAYTFKLMNLSIGTNAVIWILAAIAVVGAVMYFIADRALFSREKAAGIDSVANH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_016787_1	1.17\|43137\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43137-43169	33	NZ_CP030772	Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence	688346-688378	7	0.788
NC_016787_1	1.35\|44235\|34\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	44235-44268	34	KY613597	Corynebacterium phage LGCM-V2, complete genome	30569-30602	7	0.794
NC_016787_1	1.35\|44235\|34\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	44235-44268	34	KY624612	Corynebacterium phage LGCM-V6, complete genome	30569-30602	7	0.794
NC_016787_1	1.35\|44235\|34\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	44235-44268	34	KY566218	Corynebacterium phage LGCM-VI, complete genome	30569-30602	7	0.794
NC_016787_1	1.35\|44235\|34\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	44235-44268	34	KY624613	Corynebacterium phage LGCM-V5, complete genome	30569-30602	7	0.794
NC_016787_1	1.35\|44235\|34\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	44235-44268	34	KY624615	Corynebacterium phage LGCM-V8, complete genome	30569-30602	7	0.794
NC_016787_1	1.35\|44235\|34\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	44235-44268	34	KY624611	Corynebacterium phage LGCM-V4, complete genome	30572-30605	7	0.794
NC_016787_1	1.35\|44235\|34\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	44235-44268	34	KY624616	Corynebacterium phage LGCM-V9, complete genome	30569-30602	7	0.794
NC_016787_1	1.35\|44235\|34\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	44235-44268	34	KY624610	Corynebacterium phage LGCM-V3, complete genome	30569-30602	7	0.794
NC_016787_1	1.35\|44235\|34\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	44235-44268	34	KY624614	Corynebacterium phage LGCM-V7, complete genome	30569-30602	7	0.794
NC_016787_1	1.11\|42772\|32\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	42772-42803	32	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	211858-211889	8	0.75
NC_016787_1	1.26\|43686\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43686-43718	33	NZ_CP010679	Phaeobacter gallaeciensis strain P75 plasmid pP75_f, complete sequence	32334-32366	8	0.758
NC_016787_1	1.26\|43686\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43686-43718	33	NZ_CP010790	Phaeobacter gallaeciensis strain P63 plasmid pP63_f, complete sequence	32320-32352	8	0.758
NC_016787_1	1.27\|43747\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43747-43779	33	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	80810-80842	8	0.758
NC_016787_1	1.29\|43869\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43869-43901	33	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	232604-232636	8	0.758
NC_016787_1	1.1\|42161\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	42161-42193	33	NC_019847	Sinorhizobium meliloti GR4 plasmid pRmeGR4b, complete sequence	126404-126436	9	0.727
NC_016787_1	1.7\|42528\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	42528-42560	33	NC_009339	Mycolicibacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence	101144-101176	9	0.727
NC_016787_1	1.17\|43137\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43137-43169	33	NC_002147	Agrobacterium tumefaciens MAFF301001 plasmid pTi-SAKURA, complete sequence	44204-44236	9	0.727
NC_016787_1	1.17\|43137\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43137-43169	33	NZ_MK439386	Agrobacterium tumefaciens strain T37 plasmid pTiT37, complete sequence	77049-77081	9	0.727
NC_016787_1	1.17\|43137\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43137-43169	33	NZ_KY000041	Agrobacterium tumefaciens strain CFBP296 plasmid pTi_CFBP296, complete sequence	98834-98866	9	0.727
NC_016787_1	1.17\|43137\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43137-43169	33	NZ_KY000044	Agrobacterium fabrum strain CFBP1933 plasmid pTi_CFBP1933, complete sequence	33264-33296	9	0.727
NC_016787_1	1.17\|43137\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43137-43169	33	NZ_KY000057	Agrobacterium fabrum strain CFBP5505 plasmid pTi_CFBP5505, complete sequence	76774-76806	9	0.727
NC_016787_1	1.17\|43137\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43137-43169	33	NZ_KY000046	Agrobacterium genomosp. 1 strain CFBP2177 plasmid pTi_CFBP2177, complete sequence	87895-87927	9	0.727
NC_016787_1	1.24\|43564\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43564-43596	33	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	478785-478817	9	0.727
NC_016787_1	1.24\|43564\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43564-43596	33	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1334283-1334315	9	0.727
NC_016787_1	1.28\|43808\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43808-43840	33	NZ_LN868946	Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 4, complete sequence	66162-66194	9	0.727
NC_016787_1	1.31\|43991\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43991-44023	33	CP030478	Staphylococcus aureus strain ER02243.3 plasmid unnamed1, complete sequence	21454-21486	9	0.727
NC_016787_1	1.31\|43991\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43991-44023	33	NC_013328	Staphylococcus aureus plasmid pWBG753, complete sequence	28650-28682	9	0.727
NC_016787_1	1.31\|43991\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43991-44023	33	NZ_MH587574	Staphylococcus aureus strain WBG10514 plasmid pWBG731, complete sequence	31565-31597	9	0.727
NC_016787_1	1.31\|43991\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43991-44023	33	NZ_CP010403	Staphylococcus aureus subsp. aureus strain GR2 plasmid pGR2A, complete sequence	20027-20059	9	0.727
NC_016787_1	1.31\|43991\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43991-44023	33	NC_017350	Staphylococcus aureus subsp. aureus 11819-97 plasmid p11819-97, complete sequence	19295-19327	9	0.727
NC_016787_1	1.40\|44557\|33\|NC_016787\|PILER-CR	44557-44589	33	MK075005	Staphylococcus phage phiSP119-2, partial genome	8125-8157	9	0.727
NC_016787_1	1.44\|44359\|34\|NC_016787\|CRISPRCasFinder,CRT	44359-44392	34	NZ_CP025410	Paracoccus sp. BM15 plasmid pBM152, complete sequence	35654-35687	9	0.735
NC_016787_1	1.47\|44543\|33\|NC_016787\|CRISPRCasFinder,CRT	44543-44575	33	MK075005	Staphylococcus phage phiSP119-2, partial genome	8125-8157	9	0.727
NC_016787_1	1.2\|42222\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	42222-42254	33	NC_021909	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1e, complete sequence	133487-133519	11	0.667
NC_016787_1	1.28\|43808\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	43808-43840	33	CP052389	Klebsiella pneumoniae strain C17KP0052 plasmid pC17KP0052-1	204271-204303	11	0.667
NC_016787_1	1.33\|44113\|33\|NC_016787\|PILER-CR,CRISPRCasFinder,CRT	44113-44145	33	MG432151	Pseudomonas phage Delta, complete genome	41497-41529	11	0.667

1. spacer 1.17|43137|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030772 (Streptomyces sp. YIM 121038 plasmid pSSP121038, complete sequence) position: , mismatch: 7, identity: 0.788

cgatgaccgcggccttgtgcaggtcaagattag	CRISPR spacer
cgatgaccgcggcctggtgcaggtcggtgtggg	Protospacer
*************** *********.. .* .*

2. spacer 1.35|44235|34|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to KY613597 (Corynebacterium phage LGCM-V2, complete genome) position: , mismatch: 7, identity: 0.794

gaccacgggggatagtgcctcagctgcgagtact	CRISPR spacer
atccacgggggacagcgcctcagctgcgagcgtt	Protospacer
. **********.**.**************...*

3. spacer 1.35|44235|34|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to KY624612 (Corynebacterium phage LGCM-V6, complete genome) position: , mismatch: 7, identity: 0.794

gaccacgggggatagtgcctcagctgcgagtact	CRISPR spacer
atccacgggggacagcgcctcagctgcgagcgtt	Protospacer
. **********.**.**************...*

4. spacer 1.35|44235|34|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to KY566218 (Corynebacterium phage LGCM-VI, complete genome) position: , mismatch: 7, identity: 0.794

gaccacgggggatagtgcctcagctgcgagtact	CRISPR spacer
atccacgggggacagcgcctcagctgcgagcgtt	Protospacer
. **********.**.**************...*

5. spacer 1.35|44235|34|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to KY624613 (Corynebacterium phage LGCM-V5, complete genome) position: , mismatch: 7, identity: 0.794

gaccacgggggatagtgcctcagctgcgagtact	CRISPR spacer
atccacgggggacagcgcctcagctgcgagcgtt	Protospacer
. **********.**.**************...*

6. spacer 1.35|44235|34|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to KY624615 (Corynebacterium phage LGCM-V8, complete genome) position: , mismatch: 7, identity: 0.794

gaccacgggggatagtgcctcagctgcgagtact	CRISPR spacer
atccacgggggacagcgcctcagctgcgagcgtt	Protospacer
. **********.**.**************...*

7. spacer 1.35|44235|34|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to KY624611 (Corynebacterium phage LGCM-V4, complete genome) position: , mismatch: 7, identity: 0.794

gaccacgggggatagtgcctcagctgcgagtact	CRISPR spacer
atccacgggggacagcgcctcagctgcgagcgtt	Protospacer
. **********.**.**************...*

8. spacer 1.35|44235|34|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to KY624616 (Corynebacterium phage LGCM-V9, complete genome) position: , mismatch: 7, identity: 0.794

gaccacgggggatagtgcctcagctgcgagtact	CRISPR spacer
atccacgggggacagcgcctcagctgcgagcgtt	Protospacer
. **********.**.**************...*

9. spacer 1.35|44235|34|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to KY624610 (Corynebacterium phage LGCM-V3, complete genome) position: , mismatch: 7, identity: 0.794

gaccacgggggatagtgcctcagctgcgagtact	CRISPR spacer
atccacgggggacagcgcctcagctgcgagcgtt	Protospacer
. **********.**.**************...*

10. spacer 1.35|44235|34|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to KY624614 (Corynebacterium phage LGCM-V7, complete genome) position: , mismatch: 7, identity: 0.794

gaccacgggggatagtgcctcagctgcgagtact	CRISPR spacer
atccacgggggacagcgcctcagctgcgagcgtt	Protospacer
. **********.**.**************...*

11. spacer 1.11|42772|32|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.75

cgacacgggctatgacaccctctgggacacag	CRISPR spacer
cctcacggcctacgacaccctctgggcccagg	Protospacer
*  ***** ***.************* *  .*

12. spacer 1.26|43686|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010679 (Phaeobacter gallaeciensis strain P75 plasmid pP75_f, complete sequence) position: , mismatch: 8, identity: 0.758

ctttccgcaggccgttacgttccacggcgataa	CRISPR spacer
cagtcaccaggccgttacgttgcagggcgattg	Protospacer
*  **  ************** ** ****** .

13. spacer 1.26|43686|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010790 (Phaeobacter gallaeciensis strain P63 plasmid pP63_f, complete sequence) position: , mismatch: 8, identity: 0.758

ctttccgcaggccgttacgttccacggcgataa	CRISPR spacer
cagtcaccaggccgttacgttgcagggcgattg	Protospacer
*  **  ************** ** ****** .

14. spacer 1.27|43747|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 8, identity: 0.758

gaatttgt-----gggcgcggcgtttcgtgaggctccg	CRISPR spacer
-----tgtcgccaaggcccggcgtttcgtgatgctccg	Protospacer
     ***     .*** ************* ******

15. spacer 1.29|43869|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 8, identity: 0.758

gcttctgatcttgcggcgctacgcctacgggtg-	CRISPR spacer
cattctgatctggcagcgctacgcct-cgcccgt	Protospacer
  ********* **.*********** **  .*

16. spacer 1.1|42161|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NC_019847 (Sinorhizobium meliloti GR4 plasmid pRmeGR4b, complete sequence) position: , mismatch: 9, identity: 0.727

gaagattgaccgtctatccgaggctgtacaaaa	CRISPR spacer
aaatattgaccgcctatccgaggctgatcgtct	Protospacer
.** ********.*************  *.

17. spacer 1.7|42528|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NC_009339 (Mycolicibacterium gilvum PYR-GCK plasmid pMFLV01, complete sequence) position: , mismatch: 9, identity: 0.727

-cgccgcgtttccaacgaccaatcaccagccgct	CRISPR spacer
tcatca-acttccaacgaccaatcgccaaccgca	Protospacer
 *..*. ..***************.***.****

18. spacer 1.17|43137|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NC_002147 (Agrobacterium tumefaciens MAFF301001 plasmid pTi-SAKURA, complete sequence) position: , mismatch: 9, identity: 0.727

cgatgaccgcggccttgtgcaggtcaagattag	CRISPR spacer
caatgcccgcggccttatgcaggtcatcgacgg	Protospacer
*.*** **********.*********  . ..*

19. spacer 1.17|43137|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK439386 (Agrobacterium tumefaciens strain T37 plasmid pTiT37, complete sequence) position: , mismatch: 9, identity: 0.727

cgatgaccgcggccttgtgcaggtcaagattag	CRISPR spacer
caatgcccgcggccttatgcaggtcatcgacgg	Protospacer
*.*** **********.*********  . ..*

20. spacer 1.17|43137|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000041 (Agrobacterium tumefaciens strain CFBP296 plasmid pTi_CFBP296, complete sequence) position: , mismatch: 9, identity: 0.727

cgatgaccgcggccttgtgcaggtcaagattag	CRISPR spacer
caatgcccgcggccttatgcaggtcatcgacgg	Protospacer
*.*** **********.*********  . ..*

21. spacer 1.17|43137|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000044 (Agrobacterium fabrum strain CFBP1933 plasmid pTi_CFBP1933, complete sequence) position: , mismatch: 9, identity: 0.727

cgatgaccgcggccttgtgcaggtcaagattag	CRISPR spacer
caatgcccgcggccttatgcaggtcatcgacgg	Protospacer
*.*** **********.*********  . ..*

22. spacer 1.17|43137|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000057 (Agrobacterium fabrum strain CFBP5505 plasmid pTi_CFBP5505, complete sequence) position: , mismatch: 9, identity: 0.727

cgatgaccgcggccttgtgcaggtcaagattag	CRISPR spacer
caatgcccgcggccttatgcaggtcatcgacgg	Protospacer
*.*** **********.*********  . ..*

23. spacer 1.17|43137|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000046 (Agrobacterium genomosp. 1 strain CFBP2177 plasmid pTi_CFBP2177, complete sequence) position: , mismatch: 9, identity: 0.727

cgatgaccgcggccttgtgcaggtcaagattag	CRISPR spacer
caatgcccgcggccttatgcaggtcatcgacgg	Protospacer
*.*** **********.*********  . ..*

24. spacer 1.24|43564|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 9, identity: 0.727

gctgagctggatgccgtggagggcatccaggag	CRISPR spacer
gggcggctggacgccgtggagggcgtccacggc	Protospacer
*   .******.************.**** *.

25. spacer 1.24|43564|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 9, identity: 0.727

gctgagctggatgccgtggagggcatccaggag	CRISPR spacer
gggcggctggacgccgtggagggcgtccacggc	Protospacer
*   .******.************.**** *.

26. spacer 1.28|43808|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN868946 (Salmonella enterica subsp. enterica serovar Senftenberg strain NCTC10384 plasmid 4, complete sequence) position: , mismatch: 9, identity: 0.727

ccaccacgccgcacaggtcgctggctgtatgcg	CRISPR spacer
tcaccaccccgaacaggtcgctggcaatgtcgc	Protospacer
.****** *** ************* .*.*

27. spacer 1.31|43991|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to CP030478 (Staphylococcus aureus strain ER02243.3 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

ccggcaattacaaatgtgttagtttttccagct	CRISPR spacer
tcttctccaacaaatgttttagttttttcagct	Protospacer
.*  *  . ******** *********.*****

28. spacer 1.31|43991|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NC_013328 (Staphylococcus aureus plasmid pWBG753, complete sequence) position: , mismatch: 9, identity: 0.727

ccggcaattacaaatgtgttagtttttccagct	CRISPR spacer
tcttctccaacaaatgttttagttttttcagct	Protospacer
.*  *  . ******** *********.*****

29. spacer 1.31|43991|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MH587574 (Staphylococcus aureus strain WBG10514 plasmid pWBG731, complete sequence) position: , mismatch: 9, identity: 0.727

ccggcaattacaaatgtgttagtttttccagct	CRISPR spacer
tcttctccaacaaatgttttagttttttcagct	Protospacer
.*  *  . ******** *********.*****

30. spacer 1.31|43991|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010403 (Staphylococcus aureus subsp. aureus strain GR2 plasmid pGR2A, complete sequence) position: , mismatch: 9, identity: 0.727

ccggcaattacaaatgtgttagtttttccagct	CRISPR spacer
tcttctccaacaaatgttttagttttttcagct	Protospacer
.*  *  . ******** *********.*****

31. spacer 1.31|43991|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NC_017350 (Staphylococcus aureus subsp. aureus 11819-97 plasmid p11819-97, complete sequence) position: , mismatch: 9, identity: 0.727

ccggcaattacaaatgtgttagtttttccagct	CRISPR spacer
tcttctccaacaaatgttttagttttttcagct	Protospacer
.*  *  . ******** *********.*****

32. spacer 1.40|44557|33|NC_016787|PILER-CR matches to MK075005 (Staphylococcus phage phiSP119-2, partial genome) position: , mismatch: 9, identity: 0.727

-cattgtgcacaattcttgaactaatggaggaat	CRISPR spacer
gaaccatat-caattattgaaataatggaggaat	Protospacer
  *...*.. ***** ***** ************

33. spacer 1.44|44359|34|NC_016787|CRISPRCasFinder,CRT matches to NZ_CP025410 (Paracoccus sp. BM15 plasmid pBM152, complete sequence) position: , mismatch: 9, identity: 0.735

cgtgtgacgccggtaaaaatgccgatggcgatac	CRISPR spacer
atgaaggcgccggtaaagatggcgatggcgatat	Protospacer
   . *.**********.*** ***********.

34. spacer 1.47|44543|33|NC_016787|CRISPRCasFinder,CRT matches to MK075005 (Staphylococcus phage phiSP119-2, partial genome) position: , mismatch: 9, identity: 0.727

-cattgtgcacaattcttgaactaatggaggaat	CRISPR spacer
gaaccatat-caattattgaaataatggaggaat	Protospacer
  *...*.. ***** ***** ************

35. spacer 1.2|42222|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to NC_021909 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1e, complete sequence) position: , mismatch: 11, identity: 0.667

gtgcttgtaggcgggtgacatcgccgcgaaacg	CRISPR spacer
cattgcgtaggcgggtgacaacgtcgcgaagga	Protospacer
   . .************** **.******. .

36. spacer 1.28|43808|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to CP052389 (Klebsiella pneumoniae strain C17KP0052 plasmid pC17KP0052-1) position: , mismatch: 11, identity: 0.667

ccaccacgccgcacaggtcgctggctgtatgcg	CRISPR spacer
ccaccaggccgcacagggcgctggtcaggataa	Protospacer
****** ********** ******... .   .

37. spacer 1.33|44113|33|NC_016787|PILER-CR,CRISPRCasFinder,CRT matches to MG432151 (Pseudomonas phage Delta, complete genome) position: , mismatch: 11, identity: 0.667

ccagcaacccgtccccagatcgaccgctgtcgt	CRISPR spacer
gcagcaacccgtccccggaacgaccttcacatc	Protospacer
 ***************.** ***** ....  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

644266 : 700493

Bacillus_phage(25.0%)

transposase,protease,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014303067.1\|644266_644770_-\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_014308081.1\|644815_645439_+	sigma-70 family RNA polymerase sigma factor	A0A076YQ50	Rhizobium_phage	2.2e-08	28.5
WP_004567129.1\|645435_645687_+	mycothiol system anti-sigma-R factor	NA	NA	NA	NA
WP_014308082.1\|645691_646036_-	DUF4288 domain-containing protein	NA	NA	NA	NA
WP_004567132.1\|646376_646637_-	WhiB family transcriptional regulator	A0A2P1N2X5	Mycobacterium_phage	2.0e-11	45.1
WP_044035402.1\|647340_647730_+	hypothetical protein	NA	NA	NA	NA
WP_014308084.1\|647723_648986_-	hypothetical protein	NA	NA	NA	NA
WP_014301548.1\|648982_650293_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.3e-42	30.0
WP_004567139.1\|650509_650737_+	DUF3107 domain-containing protein	NA	NA	NA	NA
WP_014308085.1\|650739_651618_+	DUF3152 domain-containing protein	NA	NA	NA	NA
WP_014308086.1\|651640_652498_+	TIGR02569 family protein	NA	NA	NA	NA
WP_014308087.1\|652501_655684_+	ATP-dependent helicase	NA	NA	NA	NA
WP_014308088.1\|655677_658908_+	ATP-dependent helicase	A7KV33	Bacillus_phage	5.1e-19	22.9
WP_004567149.1\|658952_660041_+	potassium channel protein	NA	NA	NA	NA
WP_014308089.1\|660072_660756_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_014308090.1\|660748_662800_+	ATP-dependent DNA helicase UvrD2	S5MMD7	Bacillus_phage	4.4e-45	27.6
WP_014306618.1\|662744_663638_-	hypothetical protein	NA	NA	NA	NA
WP_014308091.1\|663673_664195_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_014308092.1\|664191_665583_-\|protease	zinc-dependent metalloprotease	NA	NA	NA	NA
WP_044035360.1\|665663_666716_+	PDZ domain-containing protein	NA	NA	NA	NA
WP_014308094.1\|666727_667426_-	hypothetical protein	NA	NA	NA	NA
WP_014303079.1\|667476_667980_-	hypothetical protein	NA	NA	NA	NA
WP_014308095.1\|668151_671115_+	UPF0182 family protein	NA	NA	NA	NA
WP_010934516.1\|671598_672168_-	sodium:glutamate symporter	NA	NA	NA	NA
WP_014308096.1\|672697_673708_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_014308097.1\|673710_674667_-	DUF418 domain-containing protein	NA	NA	NA	NA
WP_014306629.1\|674922_675090_+	hypothetical protein	NA	NA	NA	NA
WP_010934521.1\|675345_676827_+	methylmalonyl-CoA carboxytransferase subunit 5S	NA	NA	NA	NA
WP_010934522.1\|676839_678396_+	acyl-CoA carboxylase subunit beta	NA	NA	NA	NA
WP_003850577.1\|678409_678673_+	hypothetical protein	NA	NA	NA	NA
WP_003850583.1\|678697_679066_+	biotin/lipoyl-binding protein	NA	NA	NA	NA
WP_014306632.1\|679268_680360_+	hypothetical protein	NA	NA	NA	NA
WP_014308098.1\|680378_681167_-	histidinol-phosphatase	NA	NA	NA	NA
WP_014308099.1\|681223_682039_-	inositol monophosphatase family protein	NA	NA	NA	NA
WP_014308100.1\|682218_683328_+	peptide chain release factor 2	NA	NA	NA	NA
WP_014303094.1\|685106_685796_+	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	9.1e-27	38.2
WP_003850598.1\|685812_686715_+	ABC transporter permease	NA	NA	NA	NA
WP_003850600.1\|686819_687311_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.5e-36	52.2
WP_014308103.1\|689388_692322_+	type 2 lantipeptide synthetase LanM	NA	NA	NA	NA
WP_010934533.1\|694440_695319_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.6e-30	35.4
WP_010934534.1\|695318_696116_+	lantibiotic ABC transporter permease	NA	NA	NA	NA
WP_010934535.1\|696281_696548_-\|transposase	transposase	NA	NA	NA	NA
WP_013170013.1\|697582_697864_+\|transposase	transposase	NA	NA	NA	NA
WP_044026255.1\|697936_698740_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_010934538.1\|698962_699304_-	cupin domain-containing protein	NA	NA	NA	NA
WP_010934539.1\|699337_700141_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_014308107.1\|700262_700493_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_2

1761732 : 1809871

Streptococcus_phage(16.67%)

transposase,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014308372.1\|1761732_1763082_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.2e-34	36.1
WP_045143595.1\|1763124_1765716_+	class I SAM-dependent DNA methyltransferase	Q6NE04	Leptospira_phage	8.4e-158	36.8
WP_014308585.1\|1765712_1766633_+	restriction endonuclease	NA	NA	NA	NA
WP_014308587.1\|1767126_1767963_-	Abi family protein	A3QSC6	Clostridium_virus	2.5e-23	29.3
WP_003852416.1\|1768262_1770110_-	elongation factor 4	A0A2K9L6L3	Tupanvirus	4.9e-19	37.7
WP_014302216.1\|1770217_1770382_+	hypothetical protein	NA	NA	NA	NA
WP_010935319.1\|1770388_1770946_+	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_003852425.1\|1771106_1771370_+	30S ribosomal protein S20	NA	NA	NA	NA
WP_044035373.1\|1771418_1772057_-	LysE family transporter	NA	NA	NA	NA
WP_044035374.1\|1772046_1772448_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_014308590.1\|1772458_1773433_-	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_014308591.1\|1773386_1775060_-	ComEC/Rec2 family competence protein	NA	NA	NA	NA
WP_014308592.1\|1775056_1775674_-	ComEA family DNA-binding protein	NA	NA	NA	NA
WP_014308593.1\|1775792_1776614_-	DegV family protein	NA	NA	NA	NA
WP_014307180.1\|1776618_1777341_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_003852440.1\|1777347_1777815_-	ribosome silencing factor	NA	NA	NA	NA
WP_014308594.1\|1777837_1778524_-	nicotinate-nucleotide adenylyltransferase	NA	NA	NA	NA
WP_014308595.1\|1778547_1779834_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	8.3e-82	44.3
WP_014308596.1\|1779857_1780988_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.6e-57	40.5
WP_014308597.1\|1781008_1781260_-	hypothetical protein	NA	NA	NA	NA
WP_003852449.1\|1781263_1782790_-	GTPase ObgE	NA	NA	NA	NA
WP_003852453.1\|1782950_1783217_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_003852455.1\|1783257_1783563_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_014308598.1\|1783737_1786626_-	translation initiation factor IF-2 N-terminal domain-containing protein	NA	NA	NA	NA
WP_014307184.1\|1786906_1787317_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.1e-27	46.2
WP_148263398.1\|1787721_1787940_+	Lsr2 family protein	NA	NA	NA	NA
WP_014308601.1\|1788834_1789839_+	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_014308602.1\|1789832_1791059_+	aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_014308603.1\|1791071_1792202_+	acyl-CoA/acyl-ACP dehydrogenase	NA	NA	NA	NA
WP_050804394.1\|1792201_1792540_+	hypothetical protein	NA	NA	NA	NA
WP_014308604.1\|1792540_1793698_+	MFS transporter	NA	NA	NA	NA
WP_044035361.1\|1794406_1794643_+	hypothetical protein	NA	NA	NA	NA
WP_014308109.1\|1794730_1794895_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_050804400.1\|1795373_1796777_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.2e-28	34.4
WP_014308107.1\|1796841_1797072_+\|transposase	transposase	NA	NA	NA	NA
WP_014308609.1\|1798225_1798639_-	DUF4233 domain-containing protein	NA	NA	NA	NA
WP_014308610.1\|1798635_1800132_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_014309472.1\|1800128_1802837_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	2.1e-135	37.4
WP_014308612.1\|1802931_1803912_-	malate dehydrogenase	NA	NA	NA	NA
WP_014303750.1\|1804394_1805147_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_010935337.1\|1805182_1806475_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	3.3e-131	54.2
WP_014308613.1\|1806621_1809147_-	aminodeoxychorismate synthase component I	S4VNU7	Pandoravirus	2.8e-65	30.3
WP_014307190.1\|1809241_1809871_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	6.1e-38	43.5

DBSCAN-SWA_3

2245028 : 2288612

Macacine_betaherpesvirus(28.57%)

integrase,transposase,holin,tRNA

attL 2234447:2234461|attR 2292833:2292847

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2234447:2234461	attL	NA	NA	NA	NA
WP_014307479.1\|2245028_2245808_+\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_014302497.1\|2245804_2246425_+	NYN domain-containing protein	NA	NA	NA	NA
WP_014308847.1\|2246439_2248680_+	MMPL family transporter	NA	NA	NA	NA
WP_014308848.1\|2248681_2249725_+	UPF0104 family protein	NA	NA	NA	NA
WP_014302500.1\|2249721_2250078_+	DUF3054 domain-containing protein	NA	NA	NA	NA
WP_004567314.1\|2250236_2250437_+	hypothetical protein	NA	NA	NA	NA
WP_014308849.1\|2250603_2250855_+\|transposase	transposase	NA	NA	NA	NA
WP_004567317.1\|2251269_2254269_-	VaFE repeat-containing surface-anchored protein	NA	NA	NA	NA
WP_014308850.1\|2254686_2255121_-	endo-beta-N-acetylglucosaminidase	NA	NA	NA	NA
WP_014308851.1\|2255273_2255690_-	endo-beta-N-acetylglucosaminidase F2	NA	NA	NA	NA
WP_004567323.1\|2257406_2262167_-	acyltransferase domain-containing protein	NA	NA	NA	NA
WP_004567325.1\|2262265_2264080_-	AMP-binding protein	NA	NA	NA	NA
WP_004567333.1\|2264154_2265066_-	cutinase family protein	NA	NA	NA	NA
WP_004567335.1\|2265071_2265587_-	hypothetical protein	NA	NA	NA	NA
WP_014308854.1\|2265586_2267503_-	hypothetical protein	A0A2I6B2Q9	Macacine_betaherpesvirus	4.9e-38	37.6
WP_004567341.1\|2267863_2268880_-	esterase family protein	A0A2I6AZZ6	Macacine_betaherpesvirus	5.4e-36	35.1
WP_014308855.1\|2269046_2270735_-	arabinofuranosyl transferase C	NA	NA	NA	NA
WP_014308856.1\|2270743_2271721_-	decaprenyl-phosphate phosphoribosyltransferase	NA	NA	NA	NA
WP_004567346.1\|2271717_2272212_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_014308857.1\|2272211_2274197_-	glycosyltransferase	NA	NA	NA	NA
WP_044035417.1\|2274281_2274767_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_014308859.1\|2274837_2276415_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_014308860.1\|2276481_2278707_-\|holin	choline BCCT transporter BetT	A0A2I7QNT1	Vibrio_phage	3.3e-17	25.9
WP_014308861.1\|2278978_2280772_+\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	3.5e-54	29.8
WP_014308862.1\|2280957_2282121_-	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	6.5e-94	45.8
WP_014308865.1\|2282928_2283771_-	type IV toxin-antitoxin system AbiEi family antitoxin	NA	NA	NA	NA
WP_014308867.1\|2284015_2284291_-	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_014308868.1\|2284761_2286582_+	N-acetylmuramoyl-L-alanine amidase	A0A159B6I5	Gordonia_phage	8.9e-05	34.8
WP_004567362.1\|2286821_2287055_-	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_014308869.1\|2287364_2287487_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_080564351.1\|2287869_2288049_+	hypothetical protein	NA	NA	NA	NA
WP_014308870.1\|2288014_2288356_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	Q8W6R2	Burkholderia_virus	8.8e-07	42.0
WP_158307782.1\|2288336_2288612_+\|transposase	transposase	NA	NA	NA	NA
2292833:2292847	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_016787

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection