CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_019894	Singulisphaera acidiphila DSM 18658 plasmid pSINAC02, complete sequence	0 crisprs	NA	0	0	0	0
NC_019893	Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence	2 crisprs	PD-DExK	0	4	0	0
NC_019895	Singulisphaera acidiphila DSM 18658 plasmid pSINAC03, complete sequence	0 crisprs	cas4	0	0	0	0
NC_019892	Singulisphaera acidiphila DSM 18658, complete sequence	24 crisprs	csa3,cas2,cas1,cas5,cas7,cas8b3,cas3,cas6,WYL,DEDDh,csm3gr7,RT,Cas9_archaeal,cas8u1,csb2gr5,PD-DExK,DinG	3	38	14	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_019893_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019893_1

10696-10832

Orphan

Consensus_repeat	Method
AAGTATGTCCGGGCTATCGGTACT	CRISPRCasFinder

2 spacers

PD-DExK

The CRISPR arrays of NC_019893_1

>merge|NC_019893|1|10696-10832|CRISPRCasFinder
AACTATGTCCCGTTAATCGCTAGTGGTATGTCCGGGCAATCGTGGGTGCAGAGGCGAAGTATGTCCGGGCAATCGTGGAAAGTATGTCTCATTAATCGCTAAAGGACGGTCGATTCATGTCCGGTCAATCGGTATGG

>NC_019893|1|1|10696-10832|CRISPRCasFinder
AACTATGTCCCGTTAATCGCTAGT	GGTATGTCCGGGCAATCGTGGGTGCAGAGGCG
AAGTATGTCCGGGCAATCGTGGAA	AGTATGTCTCATTAATCGCTAAAGGACGGTCG
ATTCATGTCCGGTCAATCGGTATGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019893.1\|WP_015250669.1\|8106_9003_+\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NC_019893.1\|WP_015250676.1\|17340_18798_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NC_019893.1\|WP_015250673.1\|12733_14467_+\|FecR-protein	unknown	unknown	gnl\|CDD\|379155
NC_019893.1\|WP_015250674.1\|14687_15764_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019893.1\|WP_015250666.1\|2877_4305_-\|SAM-dependent-methyltransferase	unknown	unknown	unknown
NC_019893.1\|WP_015250681.1\|24522_26970_-\|DUF1553-domain-containing-protein	unknown	unknown	gnl\|CDD\|377876
NC_019893.1\|WP_015250665.1\|1297_2809_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366356
NC_019893.1\|WP_020465443.1\|19046_20036_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271196
NC_019893.1\|WP_015250679.1\|21595_22690_+\|DUF3500-domain-containing-protein	unknown	unknown	gnl\|CDD\|378789
NC_019893.1\|WP_015250678.1\|20267_21362_-\|DUF1016-family-protein	PD-DExK	COG4804_PD-DExK_CAS-I:CAS-III	gnl\|CDD\|377634
NC_019893.1\|WP_015250668.1\|7291_8107_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NC_019893.1\|WP_015250675.1\|16283_17171_+\|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl\|CDD\|130274
NC_019893.1\|WP_015250680.1\|23048_24509_-\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NC_019893.1\|WP_015250670.1\|9010_10510_-\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|370826
NC_019893.1\|WP_015243913.1\|5197_6541_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_019893.1\|WP_015250672.1\|12185_12737_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274379

Protein	Function_ID	Function_description	E-value
NC_019893.1\|WP_015250669.1\|8106_9003_+\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	9.36575e-38
NC_019893.1\|WP_015250676.1\|17340_18798_+\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	5.96593e-88
NC_019893.1\|WP_015250673.1\|12733_14467_+\|FecR-protein	gnl\|CDD\|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	8.84182e-09
NC_019893.1\|WP_015250674.1\|14687_15764_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	3.10399e-43
NC_019893.1\|WP_015250681.1\|24522_26970_-\|DUF1553-domain-containing-protein	gnl\|CDD\|377876	pfam07587, PSD1, Protein of unknown function (DUF1553). A family of proteins found in Rhodopirellula baltica.	1.17109e-105
NC_019893.1\|WP_015250665.1\|1297_2809_-\|hypothetical-protein	gnl\|CDD\|366356	pfam00884, Sulfatase, Sulfatase.	0.00196562
NC_019893.1\|WP_020465443.1\|19046_20036_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271196	cd01196, INT_C_like_6, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	2.93112e-77
NC_019893.1\|WP_015250679.1\|21595_22690_+\|DUF3500-domain-containing-protein	gnl\|CDD\|378789	pfam12006, DUF3500, Protein of unknown function (DUF3500). This family of proteins is functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 335 to 438 amino acids in length. This protein has a conserved GHH sequence motif. This protein has two completely conserved G residues that may be functionally important.	8.10734e-131
NC_019893.1\|WP_015250678.1\|20267_21362_-\|DUF1016-family-protein	gnl\|CDD\|377634	pfam06250, DUF1016, Protein of unknown function (DUF1016). Family of uncharacterized proteins found in viruses, archaea and bacteria.	2.66066e-67
NC_019893.1\|WP_015250668.1\|7291_8107_+\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	3.97224e-49
NC_019893.1\|WP_015250675.1\|16283_17171_+\|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl\|CDD\|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	5.91897e-176
NC_019893.1\|WP_015250680.1\|23048_24509_-\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	1.9862e-158
NC_019893.1\|WP_015250670.1\|9010_10510_-\|replication-initiator-protein-A	gnl\|CDD\|370826	pfam10134, RPA, Replication initiator protein A. Members of this family of bacterial proteins are single-stranded DNA binding proteins that are involved in DNA replication, repair and recombination.	1.60916e-06
NC_019893.1\|WP_015243913.1\|5197_6541_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.86613e-05
NC_019893.1\|WP_015250672.1\|12185_12737_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274379	TIGR02989, Sig-70_gvs1, RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are abundantly found in the species Rhodopirellula baltica (11), and Verrucomicrobium spinosum (16) and to a lesser extent in Gemmata obscuriglobus (2).	7.00108e-40

>NC_019893.1|WP_015250670.1|9010_10510_-|replication-initiator-protein-A
MDDWDQSIEETARIEPVAERTSAFDAGWKDELNLAEFPIAALTDRIPDGQTTLVFEDKLECRDSAPIVRRLTIMGTHKHGLPTSLDDEVLVGLIQLTKRRNNFTEAKVGFSRYELIELLGWPQSGQSYRRIEEALHRWVGVVLMYENAWWDNNAKSWVDENFHVLDNVTLYDRERRRPAPRSGKPLKAEKAPLPLSSFRWNEVIFQSFQSGNLKQLDLEFYLRLRLPTTKRMFRFLDKRFYRRSRLDFDLRTMACEHIGMSRSYAPTELKRRLKPALEELEQLGFLEPLSLEERYSYVKRGCWRIILIRGKAGQADESPMEETSELIEVLKARGVSAKIAADLVEAHPSGRIQTKVDVFDWLLRNGDKRVGKNPAGYLVASIRADYQAPGDFPTAATTEAKAAATEVEQAAEESGRQARRRARDDSERDQARETELRAAWDRLHDAERETILAEVKDENPGLGRWKKMLEPLCLVALEKRLGTTKAAQGTLFPDGGPDA
>NC_019893.1|WP_015250669.1|8106_9003_+|ParB/RepB/Spo0J-family-partition-protein
MAKPNQTDEARINRLASMTRLPAETESMTADPEARSFEGRSRLKTAAEIRLDRIVADPNQPRVEFDPESLSRLASSLKQRGQLQPIRVRWDEALDRYVVVVGERRWRAARLAGLTAIACVVASGNAAPEEILEDQLIENCLREDLRPIEQAKAFRTLLSRLGISQRQLAERLQVSPPTITRALALLELPDSIQTSVDAGEIAPHTAYEISKIDDTATQVEVAAQAAQGRLRRDDMREMVTRTPRQSRGTTPKPWVHNIDGRVRVTLAPLADDVGHEELVEALRSALATLRKKSRGQAA
>NC_019893.1|WP_015250668.1|7291_8107_+|ParA-family-protein
MRTIAFLNKKGGVGKTSTCHHLAGTLARRGLRILLVDADPQASLTQGLLGPEVARQLKPRETIAGLFDDACDADMKDLVRPASVPGVSLLAGSSRMDKFNALEPWTTGDSQYILRDSLREVSGDFDLTLIDCPPHIYLCAWAAMVAAQGIVVPLQAEDYGAQGVAAIQGSIDHVRAGANPRLTVLGFLLTMFQKSLAVHAGYAADLRAIYGDAVFETVVPHAKDFKESVMLRKPVVAYKPRSAAAKAIDALADELLARLDARVADEPRRVA
>NC_019893.1|WP_015243913.1|5197_6541_-|IS4-family-transposase
MNHDQESPAVVDLGEAVRMFHRLVPPDVLHAQKPPTLSTVFTPWVVVWLMIYQRLTCNATMATAVGELARLSADVLPDNKRAREKSFSANTGGFSRARDRLPVEMAQRAADEVSAALIAKSPPSVKGRNAFLVDGSTLSLAPTDALRKTYPPARNQHGESHWPILHLVAAHELSSGVTVRPEVGAMYGPAAIGEVPLSAGLMPRLPVGSVLIADRNFGVFAFAWLANQAGHDFVLRLTEKRFRSMVRQGKAQGKDQWELTWQPNRWERKSNPQWPADATLRVWLHEVRISEKLTLWLVSRLPDEGCELAAIYGQRQNIETDLRDLKRTLRLEEMRGRSTEMVAKELASATVAYNMANLIRRMAAARVEIAPRRLSFNRVWSLVKVLLLESLDTTDPAKIQERIDLVLRMSGQCKLANRPGRHYPREVIARRRKFPLRPRKRGLKSRK
>NC_019893.1|WP_015250666.1|2877_4305_-|SAM-dependent-methyltransferase
MHEVQGARLTASFRDPNGFVFKQAGVLYRQVNESYRDDYEHLVGSGLYGRLVDDGWLIAHQEVDLALADPGLSYKVLRPELVPFISYPYEWSFSQLKDAALLTLAIQKRALEYGMTLKDCTAYNVQFRNGRVVFIDTLSFEAYREGNPWVAYRQFCQHFLAPLALMSLTDVRLNQLFRTNIDGIPLDLASRLLPMRSKLRPSLAIHIHLHAKMQAAHAGATGSVRSANRRFGREALLGLVDHLESAIRRLHWEPGKTQWAGYYRENSYTDSALIRKEEVVAEYLDRIRPATAWDLGANTGRFSRIAAVRGITTVSFDVDPGCVELNYREVVQQGETRILPLLLDLLNPSPGTGWQNVERASLLSRGPVDLVLALALVHHLAIANNIPLLGIAEFLHQLGQSLIIEFVPKDDPQVARLLANREDIFADYHPDEFERCFQQYFDIEAANPIPDSGRVIYLMRGRGARHGGNGSSTPF
>NC_019893.1|WP_015250665.1|1297_2809_-|hypothetical-protein
MPISLALIVTLVLWLALRWLSRNGQRAALATSLLIALFFAFNQCLVVLDTILEKLSQFWVHTGYWEHPWFLLVILLVGAVPALDLIFRRLKNPVLWSNYLNVFALILVLLPASNAAMARIREPAKPIIRAEGGIPLTAKPGRLPDIYYIILDAYARSDVMKDLFGFNNAPFLDRLEQKGFFVARESRANYCQTPLSLCSTLNCDYLKTLIAPSTRDRDPLAVLIRDNLVVKSLRPLGYQFVAFASGYDVTECPQADRFLGPRHPADNFQMLVVRMTPLRYLPLKIDSWDFYTSIRERTLFTLDNLSEVAHDKEPTFTFAHILSPHHPFVFGENGEDVSPRAGNDIDAGGRRSRNLANSLAYREGYRKQAIYLTKRVEQAIDQILAKSPEPPIIILQSDHGSGLRHHLNDLERTDLRERMSILNCYYFPNRNYEGLTPRITPVNSFRVAFNNNFGGKLPILENRNQFSTYDEPFEFVDVTGRLDSGQDRGRKYTPPDIYPGMVH
>NC_019893.1|WP_015250672.1|12185_12737_+|sigma-70-family-RNA-polymerase-sigma-factor
MHSSPEEREASKGRGFLSQFLKAERRIFAYILALSPRRSDAEDLFQEASMVMWEKFDEVNPPEDFVAWGCRIAYFKICDYRKVQVRQRVTFSDAMLARMAETLATEAVTRHLDERREALECCLGKLSCRDKDFLVQRLEEGATAQTTAERTGRSVAAVYKAMAKIRRSLCDCVSRTLAMKGRA
>NC_019893.1|WP_015250673.1|12733_14467_+|FecR-protein
MMREPDRDTELRTLLEALCEESITPEQMARLEAMMMADPGAEILYLEFMQIQSDLLREFGGARSGADLSGPDPGQSGVEDVLQPASSSLRLGGRLAPGKLLLLVAAAVIGLASPIAFHAFHAARARRAGPTGLGTISDSKPSYPKVDVTRGIALVVKLEGLQWESTDHAHPSEGDILAGGRLRFRSGRLFLSMFTGVSLVVEGPADVELLSFDKVHVRSGRLRARVPEGAEGFVVSGPGSAVVDLGTEFGLNIGSDGKMQGKVFKGRVEAALLNEVGTYRRSRMMDPKSHGFNIDPQAEVIDSGIQGDDFISLSRQATSPLVLDRRYRDAVIQARPWGYWRFDSLTDGLIPNEIPGHPSLRAEGPIHLSSPGTGNRSAVFEPGSTGQYLTVNGLWEPPRHPGYSVELWFLSQGISHAALVSLLEDSPTVQVNHSSELHFKFLLELTSRVRGKLHQPASLRLLHRFPTSYNGGDNLYSKSNYMPLQWHHLVGQLNEDRMELFLDGERTSPLHVDPVYSNRASQIILGRLTTLPKHNEDTSRPFVGWMDEVAIYNRPLTIEEIRGHYRLHPASRSRPGG
>NC_019893.1|WP_015250674.1|14687_15764_+|DUF1559-domain-containing-protein
MRRQGFTLIELLVVIAIIAVLIALLLPAVQAAREAARRSQCVNNLKQMGLAIQNYHDTNGCLPPTDNATIYNSVTANANDFGMKVRILHYMEQVSLYNAFNQSIAYNLAQNGTVSATNVATFLCPSDGTTVNRGMSQYVGHNFGDCNYGNNIGTSLSFNGGQIDGPAYVIGQYPSGGINYGSSNGGVVTIASILDGTSNTAMHSEWVKGKGTAGDGLWQVYSIGTNLSTTTPAIPGGAVGWQAVLSSIGATCQTSTTQNWNTKGYSWSDGGCGIGGCYSHLQPPNKKACVYGNQKEGYSATVIWSVGTMIGASSYHSGGVNVGMLDGSVRFVKDSVSLATWGAIATKAGGEVISADSL
>NC_019893.1|WP_015250675.1|16283_17171_+|glucose-1-phosphate-thymidylyltransferase-RfbA
MFPKGIILAGGTGTRLYPITRAISKQLLPIYDKPMIYYPLSTLMLAGIRDILLISTPEDIGNFERVLGDGHQIGLSIRYAVQPQPGGLAQAFLIGREFIGSSSVGLILGDNIFYGQGFQVMLARARTAQTGATVFAYQVRDPERYGVVEFDAQGNAVSIEEKPARPRSQFAVTGLYFYDNQVVDIAANLKPSSRGELEITDVNREYLSRGQLRVERFSRGFAWLDTGTIDSLNQAANYVETIESRQGLKIACIEEVAYRMGYISSTQVENLASKLPNDYGRYLRDLLREPGQPAL
>NC_019893.1|WP_015250676.1|17340_18798_+|DUF1501-domain-containing-protein
MPSHDRLPHDHPHAFAGLNPLEREGLMVVGRRNMLKAGLMGMAGLTVPRLLRSRALASEAGRPIGGRKSVILLWMTGGPSQIDTWDPKPDRPLENRGPFGTIPTRLPGVRICEHLPRQAAMLDQFTIIRSVDARFSNHEPNKVFQTANRDAEPRINPAAEMYPAIGSIVAKHHGPNHPGMPPYVAFMKSRSHLAFAGYLGKQYDPFIADNATKLPIYDNVGVDTGRKTDAGFFQLPRGLTFERLQDRRALLGELDRMRSEIDRSGSMEGMDKFGQQAVDLLLGRQARDAFDLSKEPAAIRERYGPHLWCQQALLARRLVESGVSFVTLDLSHHTASGTWDNHGDNIPPYGGISKGLGPLLPLFDRLITTLVSDLGERGLLDDVLVIAMGEFGRTPMMGTQGSTDGRNHWNPVMSMSLAGGGLRHGQVIGSSESDGGHIKDRPVTSADLAATIYQHMGVPLDTTYLDTVGRPRAIVEDGSPISELF
>NC_019893.1|WP_020465443.1|19046_20036_-|tyrosine-type-recombinase/integrase
MDASTPKQSTTDCVNRQSHTALLLGMVPSPIRQAGEQAARRFVEFFTANIRNPNTRQAYARAVSHFFGWCAERAIALHEVEPILVAAYIEQHPGSAPSKKQALAAIRMLFDWLVVGQVLPMNPASSVRGPKHVTKRGKTPVLEADQARQLLDSLDIRSISGLRDRALIAVMVYSFARVSAVVGMNVGDYFQNGKRRWFRFHEKGGKVLEVPVHSKAEAYLDAYLTAAEIGDQTHTPLFRSITRHRTIGTTQPHRTDVFQMIKRRVKVAGLPATTGCHTFRATGITVFLQNGGTVEKAQQIAGHESPRTTKLYDRTNDAITVGEVERIVI
>NC_019893.1|WP_015250678.1|20267_21362_-|DUF1016-family-protein
MAKKHTNKGRPPAKATTTPAPRKLLTDLRALILATRTGVAQAVNSAQVLLNWQIGHRLRIDILGTKRAGYGERIIETVAEGLSADYGRGFSEKNLRHMIRFVERFPDREIVSALSRQLGWTHFRSLIYIDDALKREFYAEMCRIERWSTRTLEKKIGGMLFERTALSRKPDQLARQELAALRDEDRVSPDLVFRDPYLLDFLGLKDIYGERDLEAAILRELESFILELGAGFAFVARQKRITVDDQDYYLDLLFYHRKLRRMVAVELKMGVFQAADKGQMELYLRWLERYEMEPGEEPPLGLILCAGKSDEHVELLQLDKSGIRVAAYLTDLPPKKLLEQKLHESALRAKARLEARNSASESSD
>NC_019893.1|WP_015250679.1|21595_22690_+|DUF3500-domain-containing-protein
MNRSRSLLFVLTATALSSYATQSFAHDGPGAHTHEAPMAKASREMAEAANNLWADLTPEQKLKAGFEFTDPLRYDWHFIPRPRKGLPIKEMTGDQRALAYGLLSSGLSQRGTIKAGTIMSLEQILASIEKGSGPVRDPELYFFNIFGKPGSTDPKQPWGWRVEGHHLALNFTIVGDQGVVGGPTFMGTNPAEVKDGPRKGLRVLGEEEDLGRKLVKSLNDEQRKKGIVEDVAPKDILSLALRKAKPLEPAGILVTELNAEQKELLNSIVVLYAERLRPELAANDLGKILKAGVDKIGFAWAGGLELGQPHYYRIQGPTFLIEYDNTQNNANHVHSVWRDFESDFGDDLLKRHYESASSDHGHTK
>NC_019893.1|WP_015250680.1|23048_24509_-|DUF1501-domain-containing-protein
MATKHPGDRPASLISRRQMLQTSASGFGYLAFAGLAHDAAAQDAARRSRGSTLNAKAPHFPARAKRVIFLCMNGGPSHVDTFDYKPKLNQQSGETTSIGRDRGKAKLLGSPFKFAQHGESGLWISEVFPQLAKQADNLCLIRSMHTDLPNHSQAFTQMHTGSFQFVRPSVGAWSLYGLGSENTNLPGFVTLNPPTDNGGVRNYGSAFLPATCQGTKMGGNQIPGFYAALFGKDEEPGPPMKNIANKNLPHDLQRAQIDLIRNLNQRKLERDVHHPEIEGAIESFELAFRMQDEVPELLDMRSEPESIRKLYGVGSGLPTDRFARQCIMARRLSEAGVRFVEITAPVAWDHHFLIQDALPKSAVATDQPIAALLTDLKQRGLLEETLVIWAGEFGRTPYGQSTFGRDHNNKGYTLWMAGGGVKGGLAYGETDEYGYEAVVDPVHVHDWHATILHLLGLDHKQLTFNYGGRDFRLTDVYGNVVKEIMI
>NC_019893.1|WP_015250681.1|24522_26970_-|DUF1553-domain-containing-protein
MKRIFQIGCSLFLIGTLPLAGAEKGSAPASATGLDFFEAKIRPVLVAHCYQCHSVDAGKSKGNLLLDSREAIRAGGDSGPAIVPGDPDASLLLRAISHVDPDLKMPPKTDRLPESVINDIKSWIQAGAADPREKGTVNAIRPPVDLESGRRFWSFRKPDDHQPPASKNPGWARRNLDHFILAQLGSHGLVPREDAEPATLLRRLHFDLVGLPPTPETVHHFLESIHTDGIETALAAEVDSLLASKQYGERWGRHWLDVARFAESSGKEANISFPYAWRYRDYVIDAVNADLPFDRFLVEQIAGDLLPADSDVERARLLIATGYLAVGTKNLDESNKVQFAADLVDEQIDALTRGVMANSVACARCHDHKLDPFSMEDYYALAGIFASTKTYFGTAISPSNQVGGDPLVLPRGAGQPILHASITPEKVASLKQELATLKKEKVTTLSDALRIFWRSGGIEGELEKVDDKGQALPLAMGATDRETIGDKPLLERGEIGRPGKPVPRGFPRVVAIADAGSISSHQSGRLELARWLTHPDHPLTARVMTNRVWRHLFGVGIVSSVDNFGFSGQRPSHPELLDHLAVRLVADGWSVKKLVREIVLSRTYRQASTYDEKSFEADPENRLLWRSAKRRLDAEVIRDAMLLVSGELDTSRRVGSLVGKEIGDRPISLIGLDNRLPADLDASKHRSVYLPVLRDRLPDVLDLFDFAEPSLVTGDRETTNVPLQALYLMNSPFMEARAKALADRLMGEAGDDESRIRRAFLHCYSRIPTDDEMLMATSFLTRGKQLAGDDEKLRRQVLAICCQALLSTAEFRNLD

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Crispr_ID: NC_019893_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019893_2

11097-11248

Orphan

Consensus_repeat	Method
AAGTATGTCCGGGCTATCGGTACT	CRISPRCasFinder

2 spacers

PD-DExK

The CRISPR arrays of NC_019893_2

>merge|NC_019893|2|11097-11248|CRISPRCasFinder
AAGTATGTCCGGTTCATCGGCAGGGGAGGGGCGTTGAAGTCGGCTCAGGGAAGAGCCGGCGAAGTATGTCCGGGCTATCGGTACTCTAGCCCGACGTTCCGACTCCCCCGCTTAGCTGTGGCGAAGGTAAGTATGTCCGGGCTATCGGTACT

>NC_019893|2|2|11097-11248|CRISPRCasFinder
AAGTATGTCCGGTTCATCGGCAGG	GGAGGGGCGTTGAAGTCGGCTCAGGGAAGAGCCGGCG
AAGTATGTCCGGGCTATCGGTACT	CTAGCCCGACGTTCCGACTCCCCCGCTTAGCTGTGGCGAAGGT
AAGTATGTCCGGGCTATCGGTACT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019893.1\|WP_015250669.1\|8106_9003_+\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NC_019893.1\|WP_015250676.1\|17340_18798_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NC_019893.1\|WP_015250673.1\|12733_14467_+\|FecR-protein	unknown	unknown	gnl\|CDD\|379155
NC_019893.1\|WP_015250674.1\|14687_15764_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019893.1\|WP_015250666.1\|2877_4305_-\|SAM-dependent-methyltransferase	unknown	unknown	unknown
NC_019893.1\|WP_015250681.1\|24522_26970_-\|DUF1553-domain-containing-protein	unknown	unknown	gnl\|CDD\|377876
NC_019893.1\|WP_015250665.1\|1297_2809_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366356
NC_019893.1\|WP_020465443.1\|19046_20036_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271196
NC_019893.1\|WP_015250679.1\|21595_22690_+\|DUF3500-domain-containing-protein	unknown	unknown	gnl\|CDD\|378789
NC_019893.1\|WP_015250678.1\|20267_21362_-\|DUF1016-family-protein	PD-DExK	COG4804_PD-DExK_CAS-I:CAS-III	gnl\|CDD\|377634
NC_019893.1\|WP_015250668.1\|7291_8107_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NC_019893.1\|WP_015250675.1\|16283_17171_+\|glucose-1-phosphate-thymidylyltransferase-RfbA	unknown	unknown	gnl\|CDD\|130274
NC_019893.1\|WP_015250680.1\|23048_24509_-\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NC_019893.1\|WP_015250670.1\|9010_10510_-\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|370826
NC_019893.1\|WP_015243913.1\|5197_6541_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_019893.1\|WP_015250672.1\|12185_12737_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274379

Protein	Function_ID	Function_description	E-value
NC_019893.1\|WP_015250669.1\|8106_9003_+\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	9.36575e-38
NC_019893.1\|WP_015250676.1\|17340_18798_+\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	5.96593e-88
NC_019893.1\|WP_015250673.1\|12733_14467_+\|FecR-protein	gnl\|CDD\|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	8.84182e-09
NC_019893.1\|WP_015250674.1\|14687_15764_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	3.10399e-43
NC_019893.1\|WP_015250681.1\|24522_26970_-\|DUF1553-domain-containing-protein	gnl\|CDD\|377876	pfam07587, PSD1, Protein of unknown function (DUF1553). A family of proteins found in Rhodopirellula baltica.	1.17109e-105
NC_019893.1\|WP_015250665.1\|1297_2809_-\|hypothetical-protein	gnl\|CDD\|366356	pfam00884, Sulfatase, Sulfatase.	0.00196562
NC_019893.1\|WP_020465443.1\|19046_20036_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271196	cd01196, INT_C_like_6, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	2.93112e-77
NC_019893.1\|WP_015250679.1\|21595_22690_+\|DUF3500-domain-containing-protein	gnl\|CDD\|378789	pfam12006, DUF3500, Protein of unknown function (DUF3500). This family of proteins is functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 335 to 438 amino acids in length. This protein has a conserved GHH sequence motif. This protein has two completely conserved G residues that may be functionally important.	8.10734e-131
NC_019893.1\|WP_015250678.1\|20267_21362_-\|DUF1016-family-protein	gnl\|CDD\|377634	pfam06250, DUF1016, Protein of unknown function (DUF1016). Family of uncharacterized proteins found in viruses, archaea and bacteria.	2.66066e-67
NC_019893.1\|WP_015250668.1\|7291_8107_+\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	3.97224e-49
NC_019893.1\|WP_015250675.1\|16283_17171_+\|glucose-1-phosphate-thymidylyltransferase-RfbA	gnl\|CDD\|130274	TIGR01207, Glucose-1-phosphate_thymidylyltransferase_1, glucose-1-phosphate thymidylyltransferase, short form. Alternate name: dTDP-D-glucose synthase homotetramer This model describes a tightly conserved but broadly distributed subfamily (here designated as short form) of known and putative bacterial glucose-1-phosphate thymidylyltransferases. It is well characterized in several species as the first of four enzymes involved in the biosynthesis of dTDP-L-rhamnose, a cell wall constituent and a feedback inhibitor of the enzyme. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	5.91897e-176
NC_019893.1\|WP_015250680.1\|23048_24509_-\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	1.9862e-158
NC_019893.1\|WP_015250670.1\|9010_10510_-\|replication-initiator-protein-A	gnl\|CDD\|370826	pfam10134, RPA, Replication initiator protein A. Members of this family of bacterial proteins are single-stranded DNA binding proteins that are involved in DNA replication, repair and recombination.	1.60916e-06
NC_019893.1\|WP_015243913.1\|5197_6541_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.86613e-05
NC_019893.1\|WP_015250672.1\|12185_12737_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274379	TIGR02989, Sig-70_gvs1, RNA polymerase sigma-70 factor, Rhodopirellula/Verrucomicrobium family. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are abundantly found in the species Rhodopirellula baltica (11), and Verrucomicrobium spinosum (16) and to a lesser extent in Gemmata obscuriglobus (2).	7.00108e-40

>NC_019893.1|WP_015250670.1|9010_10510_-|replication-initiator-protein-A
MDDWDQSIEETARIEPVAERTSAFDAGWKDELNLAEFPIAALTDRIPDGQTTLVFEDKLECRDSAPIVRRLTIMGTHKHGLPTSLDDEVLVGLIQLTKRRNNFTEAKVGFSRYELIELLGWPQSGQSYRRIEEALHRWVGVVLMYENAWWDNNAKSWVDENFHVLDNVTLYDRERRRPAPRSGKPLKAEKAPLPLSSFRWNEVIFQSFQSGNLKQLDLEFYLRLRLPTTKRMFRFLDKRFYRRSRLDFDLRTMACEHIGMSRSYAPTELKRRLKPALEELEQLGFLEPLSLEERYSYVKRGCWRIILIRGKAGQADESPMEETSELIEVLKARGVSAKIAADLVEAHPSGRIQTKVDVFDWLLRNGDKRVGKNPAGYLVASIRADYQAPGDFPTAATTEAKAAATEVEQAAEESGRQARRRARDDSERDQARETELRAAWDRLHDAERETILAEVKDENPGLGRWKKMLEPLCLVALEKRLGTTKAAQGTLFPDGGPDA
>NC_019893.1|WP_015250669.1|8106_9003_+|ParB/RepB/Spo0J-family-partition-protein
MAKPNQTDEARINRLASMTRLPAETESMTADPEARSFEGRSRLKTAAEIRLDRIVADPNQPRVEFDPESLSRLASSLKQRGQLQPIRVRWDEALDRYVVVVGERRWRAARLAGLTAIACVVASGNAAPEEILEDQLIENCLREDLRPIEQAKAFRTLLSRLGISQRQLAERLQVSPPTITRALALLELPDSIQTSVDAGEIAPHTAYEISKIDDTATQVEVAAQAAQGRLRRDDMREMVTRTPRQSRGTTPKPWVHNIDGRVRVTLAPLADDVGHEELVEALRSALATLRKKSRGQAA
>NC_019893.1|WP_015250668.1|7291_8107_+|ParA-family-protein
MRTIAFLNKKGGVGKTSTCHHLAGTLARRGLRILLVDADPQASLTQGLLGPEVARQLKPRETIAGLFDDACDADMKDLVRPASVPGVSLLAGSSRMDKFNALEPWTTGDSQYILRDSLREVSGDFDLTLIDCPPHIYLCAWAAMVAAQGIVVPLQAEDYGAQGVAAIQGSIDHVRAGANPRLTVLGFLLTMFQKSLAVHAGYAADLRAIYGDAVFETVVPHAKDFKESVMLRKPVVAYKPRSAAAKAIDALADELLARLDARVADEPRRVA
>NC_019893.1|WP_015243913.1|5197_6541_-|IS4-family-transposase
MNHDQESPAVVDLGEAVRMFHRLVPPDVLHAQKPPTLSTVFTPWVVVWLMIYQRLTCNATMATAVGELARLSADVLPDNKRAREKSFSANTGGFSRARDRLPVEMAQRAADEVSAALIAKSPPSVKGRNAFLVDGSTLSLAPTDALRKTYPPARNQHGESHWPILHLVAAHELSSGVTVRPEVGAMYGPAAIGEVPLSAGLMPRLPVGSVLIADRNFGVFAFAWLANQAGHDFVLRLTEKRFRSMVRQGKAQGKDQWELTWQPNRWERKSNPQWPADATLRVWLHEVRISEKLTLWLVSRLPDEGCELAAIYGQRQNIETDLRDLKRTLRLEEMRGRSTEMVAKELASATVAYNMANLIRRMAAARVEIAPRRLSFNRVWSLVKVLLLESLDTTDPAKIQERIDLVLRMSGQCKLANRPGRHYPREVIARRRKFPLRPRKRGLKSRK
>NC_019893.1|WP_015250666.1|2877_4305_-|SAM-dependent-methyltransferase
MHEVQGARLTASFRDPNGFVFKQAGVLYRQVNESYRDDYEHLVGSGLYGRLVDDGWLIAHQEVDLALADPGLSYKVLRPELVPFISYPYEWSFSQLKDAALLTLAIQKRALEYGMTLKDCTAYNVQFRNGRVVFIDTLSFEAYREGNPWVAYRQFCQHFLAPLALMSLTDVRLNQLFRTNIDGIPLDLASRLLPMRSKLRPSLAIHIHLHAKMQAAHAGATGSVRSANRRFGREALLGLVDHLESAIRRLHWEPGKTQWAGYYRENSYTDSALIRKEEVVAEYLDRIRPATAWDLGANTGRFSRIAAVRGITTVSFDVDPGCVELNYREVVQQGETRILPLLLDLLNPSPGTGWQNVERASLLSRGPVDLVLALALVHHLAIANNIPLLGIAEFLHQLGQSLIIEFVPKDDPQVARLLANREDIFADYHPDEFERCFQQYFDIEAANPIPDSGRVIYLMRGRGARHGGNGSSTPF
>NC_019893.1|WP_015250665.1|1297_2809_-|hypothetical-protein
MPISLALIVTLVLWLALRWLSRNGQRAALATSLLIALFFAFNQCLVVLDTILEKLSQFWVHTGYWEHPWFLLVILLVGAVPALDLIFRRLKNPVLWSNYLNVFALILVLLPASNAAMARIREPAKPIIRAEGGIPLTAKPGRLPDIYYIILDAYARSDVMKDLFGFNNAPFLDRLEQKGFFVARESRANYCQTPLSLCSTLNCDYLKTLIAPSTRDRDPLAVLIRDNLVVKSLRPLGYQFVAFASGYDVTECPQADRFLGPRHPADNFQMLVVRMTPLRYLPLKIDSWDFYTSIRERTLFTLDNLSEVAHDKEPTFTFAHILSPHHPFVFGENGEDVSPRAGNDIDAGGRRSRNLANSLAYREGYRKQAIYLTKRVEQAIDQILAKSPEPPIIILQSDHGSGLRHHLNDLERTDLRERMSILNCYYFPNRNYEGLTPRITPVNSFRVAFNNNFGGKLPILENRNQFSTYDEPFEFVDVTGRLDSGQDRGRKYTPPDIYPGMVH
>NC_019893.1|WP_015250672.1|12185_12737_+|sigma-70-family-RNA-polymerase-sigma-factor
MHSSPEEREASKGRGFLSQFLKAERRIFAYILALSPRRSDAEDLFQEASMVMWEKFDEVNPPEDFVAWGCRIAYFKICDYRKVQVRQRVTFSDAMLARMAETLATEAVTRHLDERREALECCLGKLSCRDKDFLVQRLEEGATAQTTAERTGRSVAAVYKAMAKIRRSLCDCVSRTLAMKGRA
>NC_019893.1|WP_015250673.1|12733_14467_+|FecR-protein
MMREPDRDTELRTLLEALCEESITPEQMARLEAMMMADPGAEILYLEFMQIQSDLLREFGGARSGADLSGPDPGQSGVEDVLQPASSSLRLGGRLAPGKLLLLVAAAVIGLASPIAFHAFHAARARRAGPTGLGTISDSKPSYPKVDVTRGIALVVKLEGLQWESTDHAHPSEGDILAGGRLRFRSGRLFLSMFTGVSLVVEGPADVELLSFDKVHVRSGRLRARVPEGAEGFVVSGPGSAVVDLGTEFGLNIGSDGKMQGKVFKGRVEAALLNEVGTYRRSRMMDPKSHGFNIDPQAEVIDSGIQGDDFISLSRQATSPLVLDRRYRDAVIQARPWGYWRFDSLTDGLIPNEIPGHPSLRAEGPIHLSSPGTGNRSAVFEPGSTGQYLTVNGLWEPPRHPGYSVELWFLSQGISHAALVSLLEDSPTVQVNHSSELHFKFLLELTSRVRGKLHQPASLRLLHRFPTSYNGGDNLYSKSNYMPLQWHHLVGQLNEDRMELFLDGERTSPLHVDPVYSNRASQIILGRLTTLPKHNEDTSRPFVGWMDEVAIYNRPLTIEEIRGHYRLHPASRSRPGG
>NC_019893.1|WP_015250674.1|14687_15764_+|DUF1559-domain-containing-protein
MRRQGFTLIELLVVIAIIAVLIALLLPAVQAAREAARRSQCVNNLKQMGLAIQNYHDTNGCLPPTDNATIYNSVTANANDFGMKVRILHYMEQVSLYNAFNQSIAYNLAQNGTVSATNVATFLCPSDGTTVNRGMSQYVGHNFGDCNYGNNIGTSLSFNGGQIDGPAYVIGQYPSGGINYGSSNGGVVTIASILDGTSNTAMHSEWVKGKGTAGDGLWQVYSIGTNLSTTTPAIPGGAVGWQAVLSSIGATCQTSTTQNWNTKGYSWSDGGCGIGGCYSHLQPPNKKACVYGNQKEGYSATVIWSVGTMIGASSYHSGGVNVGMLDGSVRFVKDSVSLATWGAIATKAGGEVISADSL
>NC_019893.1|WP_015250675.1|16283_17171_+|glucose-1-phosphate-thymidylyltransferase-RfbA
MFPKGIILAGGTGTRLYPITRAISKQLLPIYDKPMIYYPLSTLMLAGIRDILLISTPEDIGNFERVLGDGHQIGLSIRYAVQPQPGGLAQAFLIGREFIGSSSVGLILGDNIFYGQGFQVMLARARTAQTGATVFAYQVRDPERYGVVEFDAQGNAVSIEEKPARPRSQFAVTGLYFYDNQVVDIAANLKPSSRGELEITDVNREYLSRGQLRVERFSRGFAWLDTGTIDSLNQAANYVETIESRQGLKIACIEEVAYRMGYISSTQVENLASKLPNDYGRYLRDLLREPGQPAL
>NC_019893.1|WP_015250676.1|17340_18798_+|DUF1501-domain-containing-protein
MPSHDRLPHDHPHAFAGLNPLEREGLMVVGRRNMLKAGLMGMAGLTVPRLLRSRALASEAGRPIGGRKSVILLWMTGGPSQIDTWDPKPDRPLENRGPFGTIPTRLPGVRICEHLPRQAAMLDQFTIIRSVDARFSNHEPNKVFQTANRDAEPRINPAAEMYPAIGSIVAKHHGPNHPGMPPYVAFMKSRSHLAFAGYLGKQYDPFIADNATKLPIYDNVGVDTGRKTDAGFFQLPRGLTFERLQDRRALLGELDRMRSEIDRSGSMEGMDKFGQQAVDLLLGRQARDAFDLSKEPAAIRERYGPHLWCQQALLARRLVESGVSFVTLDLSHHTASGTWDNHGDNIPPYGGISKGLGPLLPLFDRLITTLVSDLGERGLLDDVLVIAMGEFGRTPMMGTQGSTDGRNHWNPVMSMSLAGGGLRHGQVIGSSESDGGHIKDRPVTSADLAATIYQHMGVPLDTTYLDTVGRPRAIVEDGSPISELF
>NC_019893.1|WP_020465443.1|19046_20036_-|tyrosine-type-recombinase/integrase
MDASTPKQSTTDCVNRQSHTALLLGMVPSPIRQAGEQAARRFVEFFTANIRNPNTRQAYARAVSHFFGWCAERAIALHEVEPILVAAYIEQHPGSAPSKKQALAAIRMLFDWLVVGQVLPMNPASSVRGPKHVTKRGKTPVLEADQARQLLDSLDIRSISGLRDRALIAVMVYSFARVSAVVGMNVGDYFQNGKRRWFRFHEKGGKVLEVPVHSKAEAYLDAYLTAAEIGDQTHTPLFRSITRHRTIGTTQPHRTDVFQMIKRRVKVAGLPATTGCHTFRATGITVFLQNGGTVEKAQQIAGHESPRTTKLYDRTNDAITVGEVERIVI
>NC_019893.1|WP_015250678.1|20267_21362_-|DUF1016-family-protein
MAKKHTNKGRPPAKATTTPAPRKLLTDLRALILATRTGVAQAVNSAQVLLNWQIGHRLRIDILGTKRAGYGERIIETVAEGLSADYGRGFSEKNLRHMIRFVERFPDREIVSALSRQLGWTHFRSLIYIDDALKREFYAEMCRIERWSTRTLEKKIGGMLFERTALSRKPDQLARQELAALRDEDRVSPDLVFRDPYLLDFLGLKDIYGERDLEAAILRELESFILELGAGFAFVARQKRITVDDQDYYLDLLFYHRKLRRMVAVELKMGVFQAADKGQMELYLRWLERYEMEPGEEPPLGLILCAGKSDEHVELLQLDKSGIRVAAYLTDLPPKKLLEQKLHESALRAKARLEARNSASESSD
>NC_019893.1|WP_015250679.1|21595_22690_+|DUF3500-domain-containing-protein
MNRSRSLLFVLTATALSSYATQSFAHDGPGAHTHEAPMAKASREMAEAANNLWADLTPEQKLKAGFEFTDPLRYDWHFIPRPRKGLPIKEMTGDQRALAYGLLSSGLSQRGTIKAGTIMSLEQILASIEKGSGPVRDPELYFFNIFGKPGSTDPKQPWGWRVEGHHLALNFTIVGDQGVVGGPTFMGTNPAEVKDGPRKGLRVLGEEEDLGRKLVKSLNDEQRKKGIVEDVAPKDILSLALRKAKPLEPAGILVTELNAEQKELLNSIVVLYAERLRPELAANDLGKILKAGVDKIGFAWAGGLELGQPHYYRIQGPTFLIEYDNTQNNANHVHSVWRDFESDFGDDLLKRHYESASSDHGHTK
>NC_019893.1|WP_015250680.1|23048_24509_-|DUF1501-domain-containing-protein
MATKHPGDRPASLISRRQMLQTSASGFGYLAFAGLAHDAAAQDAARRSRGSTLNAKAPHFPARAKRVIFLCMNGGPSHVDTFDYKPKLNQQSGETTSIGRDRGKAKLLGSPFKFAQHGESGLWISEVFPQLAKQADNLCLIRSMHTDLPNHSQAFTQMHTGSFQFVRPSVGAWSLYGLGSENTNLPGFVTLNPPTDNGGVRNYGSAFLPATCQGTKMGGNQIPGFYAALFGKDEEPGPPMKNIANKNLPHDLQRAQIDLIRNLNQRKLERDVHHPEIEGAIESFELAFRMQDEVPELLDMRSEPESIRKLYGVGSGLPTDRFARQCIMARRLSEAGVRFVEITAPVAWDHHFLIQDALPKSAVATDQPIAALLTDLKQRGLLEETLVIWAGEFGRTPYGQSTFGRDHNNKGYTLWMAGGGVKGGLAYGETDEYGYEAVVDPVHVHDWHATILHLLGLDHKQLTFNYGGRDFRLTDVYGNVVKEIMI
>NC_019893.1|WP_015250681.1|24522_26970_-|DUF1553-domain-containing-protein
MKRIFQIGCSLFLIGTLPLAGAEKGSAPASATGLDFFEAKIRPVLVAHCYQCHSVDAGKSKGNLLLDSREAIRAGGDSGPAIVPGDPDASLLLRAISHVDPDLKMPPKTDRLPESVINDIKSWIQAGAADPREKGTVNAIRPPVDLESGRRFWSFRKPDDHQPPASKNPGWARRNLDHFILAQLGSHGLVPREDAEPATLLRRLHFDLVGLPPTPETVHHFLESIHTDGIETALAAEVDSLLASKQYGERWGRHWLDVARFAESSGKEANISFPYAWRYRDYVIDAVNADLPFDRFLVEQIAGDLLPADSDVERARLLIATGYLAVGTKNLDESNKVQFAADLVDEQIDALTRGVMANSVACARCHDHKLDPFSMEDYYALAGIFASTKTYFGTAISPSNQVGGDPLVLPRGAGQPILHASITPEKVASLKQELATLKKEKVTTLSDALRIFWRSGGIEGELEKVDDKGQALPLAMGATDRETIGDKPLLERGEIGRPGKPVPRGFPRVVAIADAGSISSHQSGRLELARWLTHPDHPLTARVMTNRVWRHLFGVGIVSSVDNFGFSGQRPSHPELLDHLAVRLVADGWSVKKLVREIVLSRTYRQASTYDEKSFEADPENRLLWRSAKRRLDAEVIRDAMLLVSGELDTSRRVGSLVGKEIGDRPISLIGLDNRLPADLDASKHRSVYLPVLRDRLPDVLDLFDFAEPSLVTGDRETTNVPLQALYLMNSPFMEARAKALADRLMGEAGDDESRIRRAFLHCYSRIPTDDEMLMATSFLTRGKQLAGDDEKLRRQVLAICCQALLSTAEFRNLD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019893_1	1.1\|10720\|32\|NC_019893\|CRISPRCasFinder	10720-10751	32	NC_019893	Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence	10720-10751	0	1.0
NC_019893_1	1.2\|10776\|32\|NC_019893\|CRISPRCasFinder	10776-10807	32	NC_019893	Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence	10776-10807	0	1.0
NC_019893_2	2.1\|11121\|37\|NC_019893\|CRISPRCasFinder	11121-11157	37	NC_019893	Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence	11121-11157	0	1.0
NC_019893_2	2.2\|11182\|43\|NC_019893\|CRISPRCasFinder	11182-11224	43	NC_019893	Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence	11182-11224	0	1.0
NC_019893_1	1.1\|10720\|32\|NC_019893\|CRISPRCasFinder	10720-10751	32	NZ_CP049359	Deinococcus wulumuqiensis R12 plasmid unnamed2, complete sequence	53962-53993	8	0.75
NC_019893_1	1.1\|10720\|32\|NC_019893\|CRISPRCasFinder	10720-10751	32	NZ_LN907829	Erwinia gerundensis isolate E_g_EM595 plasmid pEM02, complete sequence	73045-73076	8	0.75
NC_019893_1	1.1\|10720\|32\|NC_019893\|CRISPRCasFinder	10720-10751	32	NZ_CP031160	Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdB, complete sequence	31756-31787	8	0.75
NC_019893_1	1.1\|10720\|32\|NC_019893\|CRISPRCasFinder	10720-10751	32	NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	1078100-1078131	9	0.719
NC_019893_1	1.1\|10720\|32\|NC_019893\|CRISPRCasFinder	10720-10751	32	NZ_CP035000	Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence	177444-177475	9	0.719
NC_019893_1	1.1\|10720\|32\|NC_019893\|CRISPRCasFinder	10720-10751	32	MK994522	Methanobacterium virus PhiF1, complete genome	55769-55800	9	0.719

1. spacer 1.1|10720|32|NC_019893|CRISPRCasFinder matches to NC_019893 (Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence) position: , mismatch: 0, identity: 1.0

ggtatgtccgggcaatcgtgggtgcagaggcg	CRISPR spacer
ggtatgtccgggcaatcgtgggtgcagaggcg	Protospacer
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2. spacer 1.2|10776|32|NC_019893|CRISPRCasFinder matches to NC_019893 (Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence) position: , mismatch: 0, identity: 1.0

agtatgtctcattaatcgctaaaggacggtcg	CRISPR spacer
agtatgtctcattaatcgctaaaggacggtcg	Protospacer
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3. spacer 2.1|11121|37|NC_019893|CRISPRCasFinder matches to NC_019893 (Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence) position: , mismatch: 0, identity: 1.0

ggaggggcgttgaagtcggctcagggaagagccggcg	CRISPR spacer
ggaggggcgttgaagtcggctcagggaagagccggcg	Protospacer
*************************************

4. spacer 2.2|11182|43|NC_019893|CRISPRCasFinder matches to NC_019893 (Singulisphaera acidiphila DSM 18658 plasmid pSINAC01, complete sequence) position: , mismatch: 0, identity: 1.0

ctagcccgacgttccgactcccccgcttagctgtggcgaaggt	CRISPR spacer
ctagcccgacgttccgactcccccgcttagctgtggcgaaggt	Protospacer
*******************************************

5. spacer 1.1|10720|32|NC_019893|CRISPRCasFinder matches to NZ_CP049359 (Deinococcus wulumuqiensis R12 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

ggtatgtccgggcaatcgtgggtgcagaggcg	CRISPR spacer
agtatgtccgggcactcgggggtgaactgaag	Protospacer
.************* *** ***** *  *. *

6. spacer 1.1|10720|32|NC_019893|CRISPRCasFinder matches to NZ_LN907829 (Erwinia gerundensis isolate E_g_EM595 plasmid pEM02, complete sequence) position: , mismatch: 8, identity: 0.75

ggtatgtccgggcaatcgtgggtgcagaggcg	CRISPR spacer
gggagtcaggggcaatcgtagatgcagaggcg	Protospacer
** *  .  **********.*.**********

7. spacer 1.1|10720|32|NC_019893|CRISPRCasFinder matches to NZ_CP031160 (Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdB, complete sequence) position: , mismatch: 8, identity: 0.75

ggtatgtccgggcaatcgtgggtgcagaggcg	CRISPR spacer
agtatgtccgggcactcgggggtgaactgaag	Protospacer
.************* *** ***** *  *. *

8. spacer 1.1|10720|32|NC_019893|CRISPRCasFinder matches to NC_011368 (Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence) position: , mismatch: 9, identity: 0.719

ggtatgtccgggcaatcgtgggtgcagaggcg	CRISPR spacer
ggtatatcggggcaatcgtgggttcgcccttg	Protospacer
*****.** ************** *.    .*

9. spacer 1.1|10720|32|NC_019893|CRISPRCasFinder matches to NZ_CP035000 (Rhizobium acidisoli strain FH23 plasmid pRapFH23b, complete sequence) position: , mismatch: 9, identity: 0.719

ggtatgtccgggcaatcgtgggtgcagaggcg	CRISPR spacer
ggtatatcggggcaatcgtgggttcgcccttg	Protospacer
*****.** ************** *.    .*

10. spacer 1.1|10720|32|NC_019893|CRISPRCasFinder matches to MK994522 (Methanobacterium virus PhiF1, complete genome) position: , mismatch: 9, identity: 0.719

ggtatgtccgggcaatcgtgggtgcagaggcg	CRISPR spacer
gagtcgtcggggcaaccgtgggtgcagattag	Protospacer
*.  .*** ******.************   *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_019892_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_1

472413-472520

Unclear

I-A,I-B,II-B

Consensus_repeat	Method
GTGCTCAACGCCTTGCGGCATCACAGAGGTCAGCAC	CRISPRCasFinder

1 spacers

cas2,cas1,cas5,cas7,cas8b3,cas3,cas6,WYL

The CRISPR arrays of NC_019892_1

>merge|NC_019892|1|472413-472520|CRISPRCasFinder
GTGCTCAACGCCTTGCGGCATCACAGAGGTCAGCACCAGGACTGACGTGACGCTTTTGTCTCCAATCGAAAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCAGCAC

>NC_019892|1|1|472413-472520|CRISPRCasFinder
GTGCTCAACGCCTTGCGGCATCACAGAGGTCAGCAC	CAGGACTGACGTGACGCTTTTGTCTCCAATCGAAAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCAGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015243985.1\|467508_468540_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015243999.1\|497527_498292_-\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|235500
NC_019892.1\|WP_015243984.1\|466178_467381_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340850
NC_019892.1\|WP_015243992.1\|488287_489943_-\|type-I-MYXAN-CRISPR-associated-endonuclease-Cas4/Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|274899
NC_019892.1\|WP_015243998.1\|496097_497159_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_019892.1\|WP_015243989.1\|470909_472292_+\|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|143587
NC_019892.1\|WP_015243988.1\|469654_470611_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_019892.1\|WP_015243991.1\|487932_488232_-\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
NC_019892.1\|WP_015243979.1\|459901_461317_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_019892.1\|WP_015243994.1\|490681_491623_-\|DevR-family-CRISPR-associated-autoregulator	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NC_019892.1\|WP_015243997.1\|495454_496084_-\|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6	cas6	cd09703_cas6_CAS-I:CAS-III	gnl\|CDD\|370559
NC_019892.1\|WP_015243990.1\|472576_473938_-\|transposase	unknown	unknown	unknown
NC_019892.1\|WP_015243983.1\|465084_466182_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133005
NC_019892.1\|WP_015243993.1\|490048_490678_-\|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	cas5	cd09688_cas5_CAS-I-B	gnl\|CDD\|187819
NC_019892.1\|WP_015243995.1\|491676_493218_-\|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1	cas8b3	cd09713_cas8b3_CAS-I-B	gnl\|CDD\|132524
NC_019892.1\|WP_044146937.1\|463775_465020_+\|ISAzo13-like-element-ISSiac3-family-transposase	unknown	unknown	gnl\|CDD\|369439
NC_019892.1\|WP_015243986.1\|468650_469118_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015243996.1\|493205_495458_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|273707
NC_019892.1\|WP_015243980.1\|461498_462974_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133029
NC_019892.1\|WP_154673915.1\|469282_469540_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015243985.1\|467508_468540_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	8.55133e-47
NC_019892.1\|WP_015243999.1\|497527_498292_-\|glucose-1-dehydrogenase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	2.58824e-74
NC_019892.1\|WP_015243984.1\|466178_467381_+\|glycosyltransferase	gnl\|CDD\|340850	cd03823, GT4_ExpE7-like, glycosyltransferase ExpE7 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).	1.21379e-19
NC_019892.1\|WP_015243992.1\|488287_489943_-\|type-I-MYXAN-CRISPR-associated-endonuclease-Cas4/Cas1	gnl\|CDD\|274899	TIGR03983, hypothetical_protein_LA3181, CRISPR-associated endonuclease Cas1, subtype MYXAN. Members of this protein are the Cas1 endonuclease, or Cas1 domain in Cas4/Cas1 fusion proteins, of the MYXAN subtype of CRISPR/Cas systems. These systems typically feature repeats and spacers each about 36 base pairs in length. Species with this type of CRISPR system include Myxococcus xanthus, Cyanothece sp., Leptospira interrogans, Sorangium cellulosum, Anabaena variabilis ATCC 29413, etc.	1.68219e-161
NC_019892.1\|WP_015243989.1\|470909_472292_+\|carbon-nitrogen-hydrolase-family-protein	gnl\|CDD\|143587	cd07197, nitrilase, Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes. This superfamily (also known as the C-N hydrolase superfamily) contains hydrolases that break carbon-nitrogen bonds; it includes nitrilases, cyanide dihydratases, aliphatic amidases, N-terminal amidases, beta-ureidopropionases, biotinidases, pantotheinase, N-carbamyl-D-amino acid amidohydrolases, the glutaminase domain of glutamine-dependent NAD+ synthetase, apolipoprotein N-acyltransferases, and N-carbamoylputrescine amidohydrolases, among others. These enzymes depend on a Glu-Lys-Cys catalytic triad, and work through a thiol acylenzyme intermediate. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer. These oligomers include dimers, tetramers, hexamers, octamers, tetradecamers, octadecamers, as well as variable length helical arrangements and homo-oligomeric spirals. These proteins have roles in vitamin and co-enzyme metabolism, in detoxifying small molecules, in the synthesis of signaling molecules, and in the post-translational modification of proteins. They are used industrially, as biocatalysts in the fine chemical and pharmaceutical industry, in cyanide remediation, and in the treatment of toxic effluent. This superfamily has been classified previously in the literature, based on global and structure-based sequence analysis, into thirteen different enzyme classes (referred to as 1-13). This hierarchy includes those thirteen classes and a few additional subfamilies. A putative distant relative, the plasmid-borne TraB family, has not been included in the hierarchy.	1.22503e-67
NC_019892.1\|WP_015243988.1\|469654_470611_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.66624e-33
NC_019892.1\|WP_015243994.1\|490681_491623_-\|DevR-family-CRISPR-associated-autoregulator	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	6.51523e-42
NC_019892.1\|WP_015243979.1\|459901_461317_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	0.000219539
NC_019892.1\|WP_015243997.1\|495454_496084_-\|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6	gnl\|CDD\|370559	pfam09559, Cas6, Cas6 Crispr. The Cas6 Crispr family of proteins averaging 140 residues are characterized by having a GhGxxxxxGhG motif, where h indicates a hydrophobic residue, at the C-terminus. The CRISPR-Cas system is possibly a mechanism of defense against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	2.78271e-79
NC_019892.1\|WP_015243991.1\|487932_488232_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	8.04798e-23
NC_019892.1\|WP_015243983.1\|465084_466182_+\|glycosyltransferase	gnl\|CDD\|133005	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide. UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.	2.89816e-48
NC_019892.1\|WP_015243993.1\|490048_490678_-\|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	gnl\|CDD\|187819	cd09688, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	4.98132e-66
NC_019892.1\|WP_015243995.1\|491676_493218_-\|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1	gnl\|CDD\|132524	TIGR03485, hypothetical_protein_L8106_30105, CRISPR-associated protein Cas8a1/Csx13, MYXAN subtype. Members of this family are found among cas (CRISPR-Associated) genes close to CRISPR repeats in Leptospira interrogans (a spirochete), Myxococcus xanthus (a delta-proteobacterium), and Lyngbya sp. PCC 8106 (a cyanobacterium). It is found with other cas genes in Anabaena variabilis ATCC 29413. In Lyngbya sp., the protein is split into two tandem genes. This model corresponds to the N-terminal region or upstream gene; the C-terminal region is described by TIGR03486. CRISPR/cas systems are associated with prokaryotic acquired resistance to phage and other exogenous DNA.	1.14796e-50
NC_019892.1\|WP_044146937.1\|463775_465020_+\|ISAzo13-like-element-ISSiac3-family-transposase	gnl\|CDD\|369439	pfam07592, DDE_Tnp_ISAZ013, Rhodopirellula transposase DDE domain. These transposases are found in the planctomycete Rhodopirellula baltica, the cyanobacterium Nostoc, and the Gram-positive bacterium Streptomyces.	0
NC_019892.1\|WP_015243998.1\|496097_497159_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	3.4195e-40
NC_019892.1\|WP_015243996.1\|493205_495458_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	4.81835e-44
NC_019892.1\|WP_015243980.1\|461498_462974_+\|glycosyltransferase	gnl\|CDD\|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	5.32458e-53

>NC_019892.1|WP_015243989.1|470909_472292_+|carbon-nitrogen-hydrolase-family-protein
MTSFSNRLPWLVLVLVGAGLAVPSANGADEPAVAAVPSGWSSQAPRAEIQPRFTYLPEGGPNHRGSFVIEAAAREGLIGWWQKTFPVQGGRAYKFSAKRKADRIETPRQAAVPRLTWQDARGRSVLRDKPTVASYRPGGRPVAEPEFPADQGAPDAHGWTTVSAVYHVPADAAQALVELSYQWAPGGRVEWSEVALEETSTPSPRLVRLATVHLKPEKGSTNQEKCEQFAAPIAEAARQKADLVVLPETLTYFGRAGSSYADCAEPIPGPSTEYFGRLAKQHDLYIVAGLLERDKPLVYNVAVLIGPDGAIVGKYRKVTLPRGEVTGGITPGHEYPVFTTRFGRVGMMICYDGFFPEVARALSNRGAEVIAWPVWGCNPLLAAARACENHVYLVSSTFTDPKDNWTISAIYGHDGRPLARASEWGTIALTEVDLDEPLYWHSLGDFKAQLPRHRAPTPEE
>NC_019892.1|WP_015243988.1|469654_470611_+|LysR-family-transcriptional-regulator
MPSPTAQRHAYKEISLPQIRCFCDAIRLGSFKAAAKSLGLSHPTVLSQVHALEHHLGVKLVETHARGCRPTADGRLLAVMVAPLVAGFHSLEHTFQEVRGKEVQRLIVATTPRILVDDLPMCVVEFSKNWPNVQIHFEEMRMEEIPEAVETGKADLGLTTTSSPTPGNAWIAFEPAYELEVVLITPKDHPLARRRRVSARDLAEFPLVNAPPGILDPSVSIALKMLNAFQAEPRRVEVANAAAILRYVEMGFGVGLTLRVPSHLADPKFHERSLSRELGRVKVHLVWRNGSLMMPHARAFADLVKDLLNRKTSQPKTA
>NC_019892.1|WP_154673915.1|469282_469540_+|hypothetical-protein
MRQIRGESVSAWFSADALACEPTSQKHRLRGETMISEFVAEPNVNTGDMVISVSTESEQREGSAAKKNEGLIERLRYRRRVFDSI
>NC_019892.1|WP_015243986.1|468650_469118_-|hypothetical-protein
MRTFRQIRSLSGMIVMTSFLIAGCDNGVEDLRAREPISGTVTFEGQPLKEGTIQLQPATQQEGVASGGMVSDGRFEIPRAEGPVPGTYTVAIYAAAGTATSGSAEESSPTAPMPRARKTIASLRGVIPTRYNIETELKAEVKSGGPNTYAFHLKK
>NC_019892.1|WP_015243985.1|467508_468540_-|DUF1559-domain-containing-protein
MHLRRRGFTLIELLVVIAIIAVLIALLLPAVQSAREAARRAQCVNNMKQIGLACMNYESTMEVLPPGIKGSIWGTWMVFVLPYAEQQALYNAWNFLGNNTNTYSGITYGSAFNITVSTSRLNTFTCPSDTPNAPITQTYNIGGKTSWPVTSHNYAANFGNLFVFQNQTGTAGTATVPYLGAPFSDIGSPLATLVSITLAAPIGGYTDVKLSSITDGLSNTMLASEVIQGQGKGGQYNANYDLRGFAWWYGGATFETWLAPNSTLPDQMESGGYCVYPYANNPPCIAAPSVLYITNAARSRHPGGVNTVMADGSVKFVKNSINLATWRALSTTQGSEVISADAY
>NC_019892.1|WP_015243984.1|466178_467381_+|glycosyltransferase
MSLKRLLFASIHGYIDPSSGAAWASRDVLELMAARGVECRAISAGLLSYEREMSVEEILKPLGVPIRKAAPMAGMYPADSLEFDLGGVGVTLVPTASSQAERFVDPSEMNGFLARTARLIDEFRPQVMLTYGGHPASFALMKLARSRDVPVVFHLHNLAYPSRSTFDHATAILVPSEYCRRHYLQQLALESTAIPSPLIPERMVAPVRDPRYVTFINPQLSKGAAVVARIAVELHNRRPEIPLLIVEGRGAADALKAVRLDLSELRNLNRLPNLPNPRAIYRLSRMLLVPSLVRETFGRVAAEGLANGIPVLASDRGALPETLGDAGFVFTLPGRCTPQSVEAPTAHEVAPWVATIERLWDDSAWEVAHQERASVESRRWDPDLVADRYLSFFNAHGRRD
>NC_019892.1|WP_015243983.1|465084_466182_+|glycosyltransferase
MIVRNEEANLPACLASAADLFDEIVIVDTGSTDRTVEIARSFGARVFDFPWVDDFAAARNAALARATGDYAFWLDADDRIEPPHRERLRVLFDGLRSKDSAFVIRCACDADPSGGGATVVDHVRLFPVREDVRWTYRVHEQILPALRKAGITVDWTDAVVRHVGYNDPDLRQKKLRRDAAILELELAECPDDPFVLFNLGQIALESGDPLPAVGYFQRSLAGSAPGDSIICKLHALLARAYQQAGDLDSALAACDAGLAAIPDDVELLFRKGVAHRLRGEPDRAGPCWHRILTLRRPERFASVDEGIFGHVTRRNLAMLSEEQGDRAAAALHWSAVLAERPDDEGARQALGRLGQPMVGSGERPS
>NC_019892.1|WP_044146937.1|463775_465020_+|ISAzo13-like-element-ISSiac3-family-transposase
MYDPLVIAQIQRKFHLLSPEMDERRRRQWAAAEAKELGWGGVSLVAHATGLSRPTISAGMRELERPIAQRTVEGTRVRRPGGGRPTAAKSDPGLMAALESLLDPVTRGDPESPLRWTCKSTRRLAEELSRQNHGVGPRTVATLLHEAGYSLQANRKTREGVAHPDRNAQFEYINASVGRALARGQPAISVDTKKKELVGDFKNGGREWHPQGEPEEVRVHDFLDKTLGKAIPYGVYDMVNDQGWVSVGIDHDTAQFATHSIRRWWQEMGRERFPRATELLITADGGGSNGHRTRLWKVSLQALADDLGLMLSVSHFPPGTSKWNKIEHRLFSFITQNWRGKPLVSHQAIINLIAATTTKSGLIVKAVLDTNHYPLEIKVSDTELAALCLERHEFHGDWNYTIAPRIKKSRFQKL
>NC_019892.1|WP_015243980.1|461498_462974_+|glycosyltransferase
MIGPSPSASCLASVIVPCFDQLAFTRQCVASLARHTRPPWELIVVDNGSTDGTASYLAGISDVASFPVTILTNAENRGFPAGCNQGIAAARGEFVVLLNNDVVVTDGWLDQLVALARVDPAIGMVGPMSNYTCPPQVVLDAKYADLDQMDRFATTWRQQHRGQWVFAEKLSGFCLLIRRRVLEAIGGLDEGFGLGFFDDDDLAMRARSAGFELAVAVDLFVHHHGSRTFAGAGIDAESLLETNRLRFEQKWGIDSSSAQAVSLVSWGNERTATISSGIRPAMDPSHRTWTKLFGVGLPRTGTTSIAMAMLELGLRTAHACFDEALFDVGDAFFDTPVYVDYPELDRRYPGSKFILTWRDPHAWYASFARNLGPYLCRLRTQSDLDPDQLIDRRCYTLAFGADELGEDAFLKRYHDHRRCVEEYFMNRPGDLLVLDLDATIDLWEPICRFLSLPRPDRPFPRINASAIDRWLTLWHPLKLVSRTERVEAEVL
>NC_019892.1|WP_015243979.1|459901_461317_-|tetratricopeptide-repeat-protein
MNLPDGRRLVVHDLILPEVTGGRLVLWWRGDCRDGFQEWERIGTAANARVETEQGLCSITASSFQARQRLRGAIGRVVHHLVGTRSEKDWTLPNGKSATPVGGRRADLRLAWPEAESTPLDEARIKARWPGDREIRSLGPNLYLVSGLEPEQPPHEATFAEKPFQESELAITERALSTAIQSGDRRRIIIALSDLGLVLLYTGDTQRSAKVLSEALLEADRIGDLALHADVANNLAHTELYLGQPKTALDRLEPIVKYARSVGDHPAEKLALDRMARSLLELGDREGGLSCLRDAWILAAKVGDRRHEADLLWLGAIHLADAGRREEAVAAAGTAVDRLRHLHHPAAEWYAQHLESYRAGLAKITPDTFGPRWSPLGGKVDVSAEGPHSERTARPDSVATAGPLRMAVNAAKSMASFMASGFKTSSPQVYRNRLAVCTTCDQHTGTRCRVCGCITAAKAWLQHERCPFDKW
>NC_019892.1|WP_015243990.1|472576_473938_-|transposase
MKAARTLQGLQQPQSLIGYVRQFLTPTVWKQARGVVPQRRSAPRWDLQPLVVVMLAMTWATGDSESERFEKARGYYVACHESRRRPGKTFVGFQKAMRRGPMRQLRALAAGVRQQIHARLGSRRIVDGFEPMGCDGSRIECPRTPELERGLGQAGKNDAAPNVWLTAFVHLPTGLLWSWRLGPGTAAEQEHLRHLLATLSPEALIVCDAAYMGFDLVRAILGVKRSFLFRMSSRVDLYTLEVANLEDWTEGPVLYWPNYVQKRGKAPIQCRLIRIPAKGKGKGAVKRDVWLLTDVLDPARLSAATAAKFYRWRWRNEGLFRTYKRVINKVKLAGRTVALVHREAELSLLATQILLAHADLALRTATATDGPVISPRKVLIEIRKEIDAAVKPKVKCYHERLAGCRTGCRKQKSPKATRKWPRRKPHKPPKPPGLHTLTQEQKALLNKHMSAAG
>NC_019892.1|WP_015243991.1|487932_488232_-|CRISPR-associated-endonuclease-Cas2
MNDAKWWLVCYDVHDPTRLRRAAKVLEGSGQRMQESVFRCWMTPSQMHRLRWELTQVLEPNDEVLLIPLCPRCVGGMETTYSAQNHPDWPDSPEPHRII
>NC_019892.1|WP_015243992.1|488287_489943_-|type-I-MYXAN-CRISPR-associated-endonuclease-Cas4/Cas1
MTLPMVDHAPPLRVMSLHALAYCQRLFYLEEVEEIRVASAAVYAGRELHASLEADEEGERTQLELADSGLGLVGKVDALRRRDGSFLPYEHKRGRARRDGKTAMAWPSDRLQVIAYAVLIESATGQAIPEGRIRYHAENVTVRVPIDANARADLEEAVATARRLRETTERPPVAENERLCVRCSLAPVCLPEEVRQADDPEREPTRLFPPDRDGTSLHVVLPGTSVGRSGETLVVKPPDGAPPTKHAIREIDSLLVHGYCQVTTQALNLCVDREIPVHWLTTSGRHTASLTASAGQVQRRLRQYRALADEATCLRLAKSLARAKIESQHRYLLRGSRGDEQARDAMLPNLIPLRSALASLESAPNRDSLRGFEGSAAVGYFRGLDRLLSPTVPELLRYSTRSRRPPLDRFNALLGFGYGLLHTAVMRAILTAGLEPSLGFFHTPRSAAYPLVLDLMELFRVPLWDMVLIGSLNRNQWDPDADFIVTKGKTWLSDTGRRKTIQLFEDRLDETWKHPVIGYSLSYVRTLELEARLLEKEWSGEPGLFARMRLR
>NC_019892.1|WP_015243993.1|490048_490678_-|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS
MIALRVTVPIACFRKGFAREFWETEELPPPATCYGFLLSLVGEQDRRRHVGVRVCPALLGRPERSAVLRTLWRVKKLPLGSPGNTRPDYQEILTNVCLAIWLDSTEEIGTGPTLEDRVHTALDHPERINRFGGLSLGESTHLVDEVTRLSVAPGDRARAYLLNDRGRLSLPVWVDHVGSAKTRYVSGDLVETDVSAPNRDRMPRIEPLS
>NC_019892.1|WP_015243994.1|490681_491623_-|DevR-family-CRISPR-associated-autoregulator
MSLHIYGAVVTHHGTAANNRAETEGNITTLQKLLWFGKVHSSVSAEAIRFAIRRRLAEHEPTNRRWDEDLRMNVWADPIFESWASKTGKPFIDDDILGFMSADAAKEENGPETAPEPDEKKKPRAKGTTKVRRAVLEVTRAISLSPYGGDVTFNAASPGATPSAQKKGSNPVPYGTELHATRYQYGFALTPSALHKPERAAVAIESLCSLGEVAGNHGRFLYDFSPESIVFRVTHDPAPRLLYLFEGGGTTVDAPTLLARVKSGDLPAKELIIAGAFSQTSTAREVAALGATLEPGVRSAARLVCERIAAGEG
>NC_019892.1|WP_015243995.1|491676_493218_-|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1
METLSIDLFAPGMSPLHRAGLGGLATTLQWIDSKVKDDRRPPGEWSIDDRQVELKWPNPEGAKAFLKRLYELAFQIDENGLIHLPGSYGAGIPKLEVLAELQQGMSLTILQFGPNRKSDGLALKSYEIDSQTITIQHQKLTGYTHQSEWEKLVTAKGTLKPQAIISGTIAPGFVQRHVAFPSTTIEQPPGLAIALHFALIGTLSLAIDRKTGVLLVPDVEDLNLFVRRRGLMTPNSATDCRIASPADAALQAQVRLHLIEGAQKLKADRCLAVLFATKSWNEKQKARASVQEVEPDTTALERFDLAMHTLQARIALAKPTKKGEAPVPFWAESVVRPLVAENLAQGRPWYQDFRRLVVSPDGSDDAQKVRQLGYEKKGLQAMVNDHWEDRGEEAIVRSVHEAMFRRFGMIWEEVTGNQTVFNNRKERQMQRWRLAFAGAKTADDFRKALTDLWSRSGSNPVLKSSWREVLPLICDEDRWRLARDLALLALASYERPATAPKEVGSVAGNNTED
>NC_019892.1|WP_015243996.1|493205_495458_-|CRISPR-associated-helicase/endonuclease-Cas3
MTKSILLAKSDGFGRSRQSIREHTELVMKSGKRLVEVTGATQLVAVGLDPLHWLDRFRREIKITALLHDLGKANDHFQEMLIGRATRGQGLRHEAVSFLIARQPEVREWLQSVIDNNRAVELVLWAIAGHHRKFPPSAPPKDCKPEMTVYLSHPDFHDTLALGTRELSLPEPPRFGSDRKLKLISINSSLREFEDAQEDAEIFFKTASDDEKKYVSVLKACLICADVAGSIGRRGSEPMDKWISDAFLNLPQPQQLESVVGKGLKGGELRPFQIQVAEATNRVVFVQAGCGSGKTSAAYLWAAQQAPGKRLFFCYPTTGTATEGFRDYLIDPSLDAELIHGRAEVDMKILGLGDDEPGREAGTKNRQGKASEDSAGALEQWSTPLVSCTVDTVLGLVQNHRRSIYAWPSIAGAALVFDEIHSYDDNLFSALVRFLTDVRGVRCLLMTASLPQPRLQAIREALQGIGETLGGPIDGPEDLQLLKRYRREYSDSPWDRVEDVLSKGKKVLWVVNTVAEAMSLAEHPRAQKLGPTLYHSRFRYVDRVERHKAVISAFANQNTPAFAITTQVAEMSLDLSADLLITHLAPIPSLIQRLGRLNRRARPDRNDGIRPFIIIEPNSHLPYTQEQLQEARAWLALLGNEELSQADLAAHWIAQPVASSDRANHFAWLDGGFATETRHLRDASPGIDVILQRDRVAVESKQSRPEEVRIPMPPPRTGLNWRAWDEVAFCKIPPDDMIIYEEMKGAKWKP
>NC_019892.1|WP_015243997.1|495454_496084_-|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6
MPIIDLSFNIIGTTIPLDHGYSLFSALCRVVPQLHGDTRIGVHPIRGRQTAPGVLSLIDSSRIRLRLPSEEIAPYIAVAGTELELVSHRLQVGIPRVECLTAAASLGSRLVTFRGITDPTLFETNIRRQLEKRKIAGKPSLVVAARATWTGQPMRRVLRVKDKQVIGYSLRIHGLKSEESISIQEEGLGGRRRMGCGVFLPISHTENSI
>NC_019892.1|WP_015243998.1|496097_497159_-|WYL-domain-containing-protein
MMRDEPALRRQWILLRALSAQRFGLTIQEMVTESGVAAKTIRRDLELFRSLGFPLEETVGEFGRKTWKIVSSESQPPLALALNLDEVIALHLGRRLLDPLAGTPIGDAAGQAFRKIRTMFPKMALEYLERFTNFYHIATLAPADYSAQGERLDTLRTAIEDQRAVHILYQSAQATEPAFRDVYPLTLFDQKGALYLIALDPQEDKLKHYKVVRIEDVELTNIPFPRPQNFDPATYMASSFGIYQGDDDILIKVRFAPKVARYVLETKKHQSERLVKQRDGSVVAEYRLSCTNEIRSWILSFGAKAIVLEPESLRREIAEELQTLIVAYATSVSESRQHPFRGEDRHEVPGQFH
>NC_019892.1|WP_015243999.1|497527_498292_-|glucose-1-dehydrogenase
MKLTGKKAIVTGSARGIGRGCALELARAGADIVVNDRERTPEAEAVVAEIEALGRQAVLVEGDAFDHDSCGRITQRAIEALGRLDILISNPAYSRRDDFLNYSPETFRQVIQGTLAGGFSMSQHVVKHMVERGGGGKIVFISSVHARRPFPRSVAYNAGKAGLNHMALTIAGELMPYRINVNLIEPGWIDTPGEHEAFGADVMREAGPALPWGRFGKPEDIGKAAVFLVSDDADYITGSALLVDGGLLLQESHS

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Crispr_ID: NC_019892_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_2

474123-487675

Unclear

I-A,I-B,II-B

Consensus_repeat	Method
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	PILER-CR
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CRISPRCasFinder
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CRT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	PILER-CR

188 spacers

cas2,cas1,cas5,cas7,cas8b3,cas3,cas6,WYL

The CRISPR arrays of NC_019892_2

>merge|NC_019892|2|474123-487675|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
GTGCTCAACGCCTTGCGGCATCACAGAGGTCAGCACGGGAATTGTTCGCGCCCAGGCAAATCTCGGGTTGCAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATCGACCGGTAGATCCGGTGGCCATCTAGGTTGAGCGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCAACGAGGAATCATGAGCGTGGACGGCGTGAAGAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGAGTCCCGCGAGATCGGAATGCCGCGCGGGGATCGGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGAAGCCCCCTCCGACACCGGGCTCCTCTCAAAAAGGTGCTCAACGCCTTGCGACATCACATTGGTCGGAGCTTGATATGAGAATGCGTTGTGTTTTTTTTAGTGGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGTTCCACTCCGGCGAGGGGTCGAGCAAGGCTTCAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCGAAGTTATCCGCGGTGGGCGGGGCCGGGCGGAAGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATTCGATACGCTGAATCTCCTGCCTCGCCTCACTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCGAGCTGCTTACGGGCGAGCTGCCCCTCTGGGGAAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCCTTGGGGTCGACGGGCTTGACAAGGAACCGCTCGGACATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCGGCAGCGACGGGAGCGTTTGGTCGAGATGGGATCGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCGGATTGCCCCCCCACCCGATGGATCGGGTGGGGGGGGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTTATCACCATCGCCTGGCTTCAGGGTCGCATGCAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGAGAAGGAACGCGCGCTCGAGCTTCGCGACACGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCGTGTCGGAGACACTCCTAGTTCAGCCGCCAGAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAATAGTACGAGTTTGAGGAGGAAGCACGATATCTGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCTTCTATAACTTCGTCAACAAAGACGCCCAGAGCTAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAGACGTGACTTGGCATAGACTCCGTCATACCTTCGGAAGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCTCCATAGTGGCGGCGGGTTTGGCGAGCAGCACAGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGATCCTCGCCAGAGGACTCGATCGAGAATTGAAGGTGCTCAACGTCTTGCGGCATCACAGAGGTCGGCACATCACGATACTCGACCTTGGCATTGGCGCAGTCGACATGTGCTCAACGCCTTGCAGCATCACAGAGGTCGGCACCCTGTGCGTGCGCGTCACGTGTACGTGCGTGCGTAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCTGCGAAGCGGTGTAATAATCGAAGCCATGTTCGTGCTCAACGCCTTGCGGCATCACAGAGGCCGGCACCTTCAATGGCGAAGTCCTCGCCCAGGTCGATGGCCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGCCTACCGGCCTCTGACTCGGTTCGAGGATCTGAAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCTGAGCTGCGAGAGCGCCAGGATTGGCATGTTGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACCTCCAGCGAACGAGCGAGCAGGTATGCCTGATCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACAACCTGATATGCGAGCAGGCTGTGCTTGCCCATGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGACGACGCGCGGTCCCTCGCGATCAGGTTTGCCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTTGAACTCTTTGTTGATAGACTTGTCGGCTTTCAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCGGCAACGCTGGGATAGAGTTGGGTCTGGTAACGCCAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCAGCGTGACGGTGCCGATCGCTACTTTCTGCTCGCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCATATCCTCGATTGGGCGGCCGATCTCGGCTATCCCGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAGCGAGGTTGCGTAGGGGTTCTTCACTGGGATATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGAAACGACTGTTTTGACTACGGCGACTTGGCCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGAGTTGAGCACCGGGTCAGCCCGGATCATGCTGACGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAAAGGGTCGTGATCCGTGGGGCCGGCGGCGTCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCAGTGGCTCGTGTCGGCGGAGTATGGAGGTAGGAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGCGATGGAGAGCGACCAATACACTGCGTCTGAGGAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAATCGGAGACGGAAAGCAGGTTCCGCGACGGGAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATCCAAGCGATGCCGGTTTGCCGCTTGGAGAGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCCACAGGTGTCACCGCGCAGGCCGATGGGCAGGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGTACGCGACCGAGGCGAGAGACGGCTACACGGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTTAGTCGCCATCGGTTTCTAAGTTTCAGCTTACGCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCTACGACGGCTGAATCCGAAATCTATGGTCGGGCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCTCGGCCTTGAGCCGTTCGATCATCGCGGCGAGCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGTCGTCGAGGTCGACCAGGCTGGCCGAATTGCGGAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCTGGCTCACCAGGGCCAGGGCGAGTAGGAGGACGTGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGGCGTTTCCCGGTCCGTCCAGGACGCCACGGATGGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCACCCGATCAGGTGTTCAGACCCGGCCCGGGACTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCGCGGCCAACTCGCTCTTGGCGTCCCGGTAGAATGCCGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCCGCAACCGCAATCGTGGTTCGAGCTCGGCGCCGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGGCGGCCTCTCCCCCTCTCTCTGGCTCGCCGTTGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCCGGACCTGGAAGATATCACCAAGCCTGGATGCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGCCTGGTGATCGTCACCGGCCCGGGGCAGACGGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGAGGTCCCCGTGACGGCCGAATCCACGTTTGCCGGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATTTTGCCGAGCCGGATGACAATCCCGCCGAAGCCCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGCGGTGAATGCTCGATTCCGATCCCGTGCCCGACCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCATCGTCCGACCAGATTGTTGCCGCGACTTGACCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACACCGCAATCACCCAGATCACGACCGGCGCATCGAACCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGGGTTTCTACGCGCGGCTCACCGGCTCGGCGAACCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACCTCCACCAGACCGTCGCGATCCGAACCGAGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGCGGGCGGGCTCCGCTTGGATTTCCCGGGCGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCCGAGGAAGTTGGGCCGACGGCCGCCGACGGCTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGTTTTTGCGTTCAACTCGTTCTCTTGTTCGTTCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCTTCGCCAGCTTGTCTTTCGCCTGCTCTGTGATCCGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTTCGGCTTCGGAACGACTATCACGATCTTGCCGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAACGCCATCCGTGATGGGATAAAGCGCAACGACGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCGGCACCGGCCGGGTCGGGCCCGTCGTTGTCGTCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCAAGCCGCGCGGATCTACCGCAAGGCGATGGAGGCTGTGCTCAACGCCTTGCGGCATCACAGAGATCGGCACACCGCCGTCATTGATCGTCCAAAATTTAGGCGACAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATGCGCGGGTACAAACCGGGCAAGGCATCGGGTGGAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCGGTCGGACCTGGCTTATCCACCTCCTGGCCGATCGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGCCAACTCCGGGCCGGCTCGAGGAGATCGCTTGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATCACCGATGAGGGTGTTTGGCCAGCCACCGGCCAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCTGTAGTGCCGCAGTCCCCGCAAGGGCTGGAGTAACTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCGGACGAAGCTACCCACAGGGGAAGCCATGTCTTCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCTTCAGGGTGCCGTCCTGGTACATGCGGAAGAGTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACGTCACCGGAAGGCCGGGCAATCTGGCGTGAATTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCGGAAAACTCTCCTTCGAGCGCCTGAGCGGCTGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATCATGAACGGTAATTGGCTCGTAAATAAGAACGTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACGAGCTGCCTGGGGGCATTCGAGACCGACGAGAGGTCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTGTCCTTTCGCAGACATCTTGCGAGCGTAAGTCAAGGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCACGGATCCACCCAGCAACCTCGCTCATGCGCACCCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCGATCCCCGACGAGACGGTGTAAGCCGACGCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACGGCCCCAACCAGGCATGGCAAATCTTGGGGCAGCATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCAGCTCCCGAAGTCTACCGCGATGGGATGGGCTAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGAGTGCTTGCGTAGCCATAACCAGGGCTGTGGGCAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCCGACATTCCGGAGCCATCCGGCCCGTTTTATTCGAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCTGACGGCCCAATCTCGGCCGCCCAGGGTCAGGCAACGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGTCGATCCTCGCGTCACGAGGCGTCGACCAGCGAATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCGAGGCGACGCACCGCTGCAGGTCCGCCTTTGACAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCTCTACGACGGCAACGCGCCCGCGACGGCGAACACCGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACGGATCCGGACTTGGTCCTTGAGCAGCTTACGAAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCGGAGAACGCGTGTGTGGTCGGACCGGAATCGGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGAGAGTGAGGATCGGGAACGCGAGCAACACCAGGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGATAATCATCGCGCTGGTCGTTTCGGCGGTCGCCGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCGATCGCCTCGAAGATTTGGCGGTGGCGGGCCGCAAGTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCAACGACTCTCGCGGTCAGCCAACTCGGCGTTGGTCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGAGACAGCGCTTTGGCTTCCTGAACCGCTTCGGAATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGTATCGTCGCGGGCCTCGATATCCTTGTTCGTAGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGACTCCGTTGCGGAGTTCGTCCCTAGGCGACCTGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCAGAACGCCATCACTAGATCATTCCAGTTGCCGAAGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCAACCCATGTTTGCAGAAACACGCGACCTTCTTCGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATCATCTTCGGCGACTCGGCCGGCACGATCATCGCGGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAGAACAGTTCGGCGGCTGAGGCTGTGTCGTAGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGGACTTGATCGGCGGCGGAAGCGCGTCCACACCCGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTTCAACCATTGTTCCCCCAGCCACGAACACGACCGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTTTGGAGAAATCCAGTGAGCAATGGAAGGCAGAATTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCACCAGCAACGAGAAGTGGTAGACGTCCAAGTCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCCACGGCCGCGAGACCGAATGTCCTTTCGCAGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCGCACTGCACCGCCACACTTCGACGACGCGATCATGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATGGTGGGGAGAGGGACGCCCGTGGCGACCGTGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCACCCGCCTCATCGCCGGGTTGTGGTACCCGGCGATCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAATTGGTTCATCTGCCTTCACGCCCTCATTCCGACGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCATCTCGCCGTCCTCCCACCCGGTTTCGACCGACGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGTGTCCACGGGGATGCTACCAGGAAGGGTATCACGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCCGTGGCGCAACGCGGGTCTCCTTCAGCGGGGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGTGACCCCCAAACGGATCAGCGGTGCGAAGTTCGGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAATACGTGCCGACGATCCCGATGAAGGCCCGCCCGGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCTGGACCGGTCGAGGAGTTTCTCTTGGACGAGGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGGTAGTTGCCGTTCCGGTCTGCCCTCATGCTCGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCCGCTTACCGGTGTCCAGATGACCGGAGCCCAGTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCAATTCCTCTGGCTTCACTCCGAGGCCCTTCGCGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCTCAGGACGGGAGACACCGAAGCCACATCTTCACTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGAAGTTGCTTGAGCGCACCCTGCCGATCACCGGCCCCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCCGTGCGATCTTGCTGTCCCTGCTGGACACGGCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGTGCTTGCCTTCATGCTCTATGGACTCCACCAAGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCCGATCATATTCACCGGCCACTCGGTGCCGGCCATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCGGCCCGCGAGTGTCGCGCGGACCTCGTCATCCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCGCTCCGGCACAAGATCGGGCTCGTGATCCTCGACTAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCGAGCGGCACCACGAGAGACCGGCAAAGTACGCGTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAGGTTGAAAGGCGACTTCCACGCATACACTCGCCAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGACGAGGGCCGCACTGAAGCTGAGAGAACCTATCGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCTTCCAAACCCACAAAGGTTTCATGTTCTCGTAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATTTGTTACCGGCAGAGTCCTTATGCTTCTTCATAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCAAGAGAGTTGTGGACTCGGCCACAGAAGCAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGATTTCCTCTTCGTCGTGGACTCTTTCAAGGCTAGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCGTCACGACGGCGCGGGGCCTGGTTGGGTAGCTGTAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTGCATGTCGTGGTCGGCCTGATGGTGCCGATCACGGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCACCCTCTCGGAGGACGGGGCGTCATCATTGAGTCAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCGATGCCGGTCAGACGGGTGTACTCCTGAGCGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAACCGAAGGCCCCTCGATCGTCTTGCCTCGCTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGAAGGCCTGATCTGCGTCAATGCAGACGACCGCCCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCAGATTGCGCAGGGGAAAGCCACGGGAGTCATACCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGAGGAGTCTCCGATTAAGCATGTGATTCCTTCGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCAAGCAATTCGACCGGATGATTCGCCGCCGGGTGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATCGCGGAACGCACCGTCGTGATCGACCGGACCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCATAGCGGGACTCCACGCTGTTTGACAGTAAAATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGATCCCGGGCGCATGGATGCAATGCCATGCCGCCGAATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCCTTCCCGCACGATCTCTTTCATCCGTGGCCCAAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACGGTCGAGTTCGACGCCAAGGGGGCTCTGGCTGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGCGATCGCAAAGCCGATGTCCCGCTGCCAGGCCGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGATCATCACGGCCGAACAGCGGGCCGATCCGAAATTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCAGGCTGCCGACCGCGATCGGCAGAAAAAATTGAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAACGGCGACGGGGTGACTCCCTCGGTTCCAATCAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGTGAGACTATTGTCCCCGTACCCCACAGTGAGTGATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCCGACCGAGCCGACGGCAACCGTGGTGTTGTGGGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACCACGGTGTAGCCCGCATCCCGGTAGGGGCGGCTCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGTAGGGATGGCCGTCTGGAGGGAGCGGCTCGAAAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACGTCTTCACGGTCGCCCCTCCCGGCTTTGCCGAGCAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAACCGAAGCATCAAGCGAAGGCTGTTCCGGCCGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGACGTTGACTGCGGCGAAGTCCTCGACGTGATGGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCACCACCGTCGCCTTTGACTTCAAATCAAAGAACTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCCGATCAGCGAGCTGACGGGTAATCCTTGCGGGTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCGACTCGGGCGAACAGTGCACTCAGTGTGGCGGTTTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACATGGGCATCGACCTCAAGCGGTTCGTGGCCAATCCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCTGACCTGGTTGGTTCCGGAGCCGTCCGCCAAATAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAGGAGTGTTCGACTCCGAGGAGAAAGCCACTGCCGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCCAGCGCGACCATCGCGGCGTTGGTCGGAGGCCCTCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACCTCTTCGGTCTGTGGGATAACCCGATTGTCGCCAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCAACGTATCGTTCGCGGCCAGTTCGAAGTTCGTACGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGAGCTTGAGAGTCGAACCGTCGACGCCAACGATCTCCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGCCAGGTCGGTCCCGAATCGTGAGCCGAAACGGCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACCGCGTCTCCTGGAGCAGAGACTGAATCGCCTCGAGAAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCGAGGGCGACGAGCGGAGTGAGGTCGACTGACGGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTGGCTCCCTTGCCGATCGCGTCCTGCATCAGCTTGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAAAGAACACCTTTCTCCCTCTGGCCGAGAAAGCCCCGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGACTCGGCTTCATGCGATTTCCTCTAACCCTCTCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAATGCGTCGAGCTCGGCCCAAGCCTGGTCCCGCACGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGAACTTACTCCCGAGCAGCATCGTCGCGCACTGGAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCTGCGAGAGGCAGCGAGCCACGTACTCAGAGGAGCTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACACAAACCGGTCCGCGATCCGATCACCGCACTCGAGCAGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGCGGTCGATGCCGGCTCGATTGCCCTAGCCCTGGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTGCGAACACTTCGAGCCAGGAGAGGGTGGGTGGCGGGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACTCTCAGTCTCTCGATTTCTATCGCGGCCCGCTTGGCGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACAGGCCGGGGCCTCCTCGAGACCGAAAAGGCTTAATGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC

>NC_019892|2|1|474123-474447|PILER-CR
GTGCTCAACGCCTTGCGGCATCACAGAGGTCAGCAC	GGGAATTGTTCGCGCCCAGGCAAATCTCGGGTTGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCGACCGGTAGATCCGGTGGCCATCTAGGTTGAGCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAACGAGGAATCATGAGCGTGGACGGCGTGAAGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTCCCGCGAGATCGGAATGCCGCGCGGGGATCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGAAGCCCCCTCCGACACCGGGCTCCTCTCAAAAAGGTGCTCAACGCCTTGCGACATCACATTGGTCGGAGCTTGATATGAGAATGCGTTGTGTTTTTTTTAGTGGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTTCCACTCCGGCGAGGGGTCGAGCAAGGCTTCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGAAGTTATCCGCGGTGGGCGGGGCCGGGCGGAAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTCGATACGCTGAATCTCCTGCCTCGCCTCACTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGAGCTGCTTACGGGCGAGCTGCCCCTCTGGGGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCTTGGGGTCGACGGGCTTGACAAGGAACCGCTCGGACAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCAGCGACGGGAGCGTTTGGTCGAGATGGGATCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGATTGCCCCCCCACCCGATGGATCGGGTGGGGG
GGGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTATCACCATCGCCTGGCTTCAGGGTCGCATGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGAAGGAACGCGCGCTCGAGCTTCGCGACACGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGTGTCGGAGACACTCCTAGTTCAGCCGCCAGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAATAGTACGAGTTTGAGGAGGAAGCACGATATCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTTCTATAACTTCGTCAACAAAGACGCCCAGAGCTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGACGTGACTTGGCATAGACTCCGTCATACCTTCGGAAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCCATAGTGGCGGCGGGTTTGGCGAGCAGCACAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCCTCGCCAGAGGACTCGATCGAGAATTGAAG
GTGCTCAACGTCTTGCGGCATCACAGAGGTCGGCAC	ATCACGATACTCGACCTTGGCATTGGCGCAGTCGACAT
GTGCTCAACGCCTTGCAGCATCACAGAGGTCGGCAC	CCTGTGCGTGCGCGTCACGTGTACGTGCGTGCGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTGCGAAGCGGTGTAATAATCGAAGCCATGTTC
GTGCTCAACGCCTTGCGGCATCACAGAGGCCGGCAC	CTTCAATGGCGAAGTCCTCGCCCAGGTCGATGGCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCCTACCGGCCTCTGACTCGGTTCGAGGATCTGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCTGAGCTGCGAGAGCGCCAGGATTGGCATGTTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCCAGCGAACGAGCGAGCAGGTATGCCTGATC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACAACCTGATATGCGAGCAGGCTGTGCTTGCCCATGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGACGACGCGCGGTCCCTCGCGATCAGGTTTGCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTGAACTCTTTGTTGATAGACTTGTCGGCTTTCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCAACGCTGGGATAGAGTTGGGTCTGGTAACGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCAGCGTGACGGTGCCGATCGCTACTTTCTGCTCGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATATCCTCGATTGGGCGGCCGATCTCGGCTATCCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGCGAGGTTGCGTAGGGGTTCTTCACTGGGATAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAAACGACTGTTTTGACTACGGCGACTTGGCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTTGAGCACCGGGTCAGCCCGGATCATGCTGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAAAGGGTCGTGATCCGTGGGGCCGGCGGCGTCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGTGGCTCGTGTCGGCGGAGTATGGAGGTAGGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCGATGGAGAGCGACCAATACACTGCGTCTGAGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAATCGGAGACGGAAAGCAGGTTCCGCGACGGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCCAAGCGATGCCGGTTTGCCGCTTGGAGAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCACAGGTGTCACCGCGCAGGCCGATGGGCAGGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGTACGCGACCGAGGCGAGAGACGGCTACACGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTAGTCGCCATCGGTTTCTAAGTTTCAGCTTACGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTACGACGGCTGAATCCGAAATCTATGGTCGGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCGGCCTTGAGCCGTTCGATCATCGCGGCGAGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTCGTCGAGGTCGACCAGGCTGGCCGAATTGCGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGGCTCACCAGGGCCAGGGCGAGTAGGAGGACGTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCGTTTCCCGGTCCGTCCAGGACGCCACGGATGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCACCCGATCAGGTGTTCAGACCCGGCCCGGGACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGCGGCCAACTCGCTCTTGGCGTCCCGGTAGAATGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGCAACCGCAATCGTGGTTCGAGCTCGGCGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCGGCCTCTCCCCCTCTCTCTGGCTCGCCGTTGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGGACCTGGAAGATATCACCAAGCCTGGATGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCCTGGTGATCGTCACCGGCCCGGGGCAGACGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGGTCCCCGTGACGGCCGAATCCACGTTTGCCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTTTGCCGAGCCGGATGACAATCCCGCCGAAGCCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCGGTGAATGCTCGATTCCGATCCCGTGCCCGACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCATCGTCCGACCAGATTGTTGCCGCGACTTGACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACACCGCAATCACCCAGATCACGACCGGCGCATCGAACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGGGTTTCTACGCGCGGCTCACCGGCTCGGCGAACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCCACCAGACCGTCGCGATCCGAACCGAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCGGGCGGGCTCCGCTTGGATTTCCCGGGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCGAGGAAGTTGGGCCGACGGCCGCCGACGGCTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTTTTTGCGTTCAACTCGTTCTCTTGTTCGTTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTTCGCCAGCTTGTCTTTCGCCTGCTCTGTGATCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTCGGCTTCGGAACGACTATCACGATCTTGCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACGCCATCCGTGATGGGATAAAGCGCAACGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCACCGGCCGGGTCGGGCCCGTCGTTGTCGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAAGCCGCGCGGATCTACCGCAAGGCGATGGAGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGATCGGCAC	ACCGCCGTCATTGATCGTCCAAAATTTAGGCGACAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGCGCGGGTACAAACCGGGCAAGGCATCGGGTGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGTCGGACCTGGCTTATCCACCTCCTGGCCGATCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCCAACTCCGGGCCGGCTCGAGGAGATCGCTTGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCACCGATGAGGGTGTTTGGCCAGCCACCGGCCAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGTAGTGCCGCAGTCCCCGCAAGGGCTGGAGTAACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGACGAAGCTACCCACAGGGGAAGCCATGTCTTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTTCAGGGTGCCGTCCTGGTACATGCGGAAGAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGTCACCGGAAGGCCGGGCAATCTGGCGTGAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGGAAAACTCTCCTTCGAGCGCCTGAGCGGCTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCATGAACGGTAATTGGCTCGTAAATAAGAACGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGAGCTGCCTGGGGGCATTCGAGACCGACGAGAGGTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGTCCTTTCGCAGACATCTTGCGAGCGTAAGTCAAGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCACGGATCCACCCAGCAACCTCGCTCATGCGCACCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGATCCCCGACGAGACGGTGTAAGCCGACGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGCCCCAACCAGGCATGGCAAATCTTGGGGCAGCAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGCTCCCGAAGTCTACCGCGATGGGATGGGCTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTGCTTGCGTAGCCATAACCAGGGCTGTGGGCAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCGACATTCCGGAGCCATCCGGCCCGTTTTATTCGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGACGGCCCAATCTCGGCCGCCCAGGGTCAGGCAAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTCGATCCTCGCGTCACGAGGCGTCGACCAGCGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGGCGACGCACCGCTGCAGGTCCGCCTTTGACA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCTACGACGGCAACGCGCCCGCGACGGCGAACACCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGATCCGGACTTGGTCCTTGAGCAGCTTACGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGGAGAACGCGTGTGTGGTCGGACCGGAATCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGAGTGAGGATCGGGAACGCGAGCAACACCAGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATAATCATCGCGCTGGTCGTTTCGGCGGTCGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGATCGCCTCGAAGATTTGGCGGTGGCGGGCCGCAAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAACGACTCTCGCGGTCAGCCAACTCGGCGTTGGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAGACAGCGCTTTGGCTTCCTGAACCGCTTCGGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTATCGTCGCGGGCCTCGATATCCTTGTTCGTAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACTCCGTTGCGGAGTTCGTCCCTAGGCGACCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGAACGCCATCACTAGATCATTCCAGTTGCCGAAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAACCCATGTTTGCAGAAACACGCGACCTTCTTCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCATCTTCGGCGACTCGGCCGGCACGATCATCGCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGAACAGTTCGGCGGCTGAGGCTGTGTCGTAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGACTTGATCGGCGGCGGAAGCGCGTCCACACCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTCAACCATTGTTCCCCCAGCCACGAACACGACCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTTGGAGAAATCCAGTGAGCAATGGAAGGCAGAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCAGCAACGAGAAGTGGTAGACGTCCAAGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCACGGCCGCGAGACCGAATGTCCTTTCGCAGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGCACTGCACCGCCACACTTCGACGACGCGATCATG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGGTGGGGAGAGGGACGCCCGTGGCGACCGTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCCGCCTCATCGCCGGGTTGTGGTACCCGGCGATC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATTGGTTCATCTGCCTTCACGCCCTCATTCCGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATCTCGCCGTCCTCCCACCCGGTTTCGACCGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTGTCCACGGGGATGCTACCAGGAAGGGTATCACGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGTGGCGCAACGCGGGTCTCCTTCAGCGGGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTGACCCCCAAACGGATCAGCGGTGCGAAGTTCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATACGTGCCGACGATCCCGATGAAGGCCCGCCCGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGGACCGGTCGAGGAGTTTCTCTTGGACGAGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGTAGTTGCCGTTCCGGTCTGCCCTCATGCTCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGCTTACCGGTGTCCAGATGACCGGAGCCCAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCAATTCCTCTGGCTTCACTCCGAGGCCCTTCGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCTCAGGACGGGAGACACCGAAGCCACATCTTCACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAAGTTGCTTGAGCGCACCCTGCCGATCACCGGCCCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGTGCGATCTTGCTGTCCCTGCTGGACACGGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTGCTTGCCTTCATGCTCTATGGACTCCACCAAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGATCATATTCACCGGCCACTCGGTGCCGGCCAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGGCCCGCGAGTGTCGCGCGGACCTCGTCATCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGCTCCGGCACAAGATCGGGCTCGTGATCCTCGACTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGCGGCACCACGAGAGACCGGCAAAGTACGCGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGGTTGAAAGGCGACTTCCACGCATACACTCGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACGAGGGCCGCACTGAAGCTGAGAGAACCTATCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTTCCAAACCCACAAAGGTTTCATGTTCTCGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTTGTTACCGGCAGAGTCCTTATGCTTCTTCATA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAAGAGAGTTGTGGACTCGGCCACAGAAGCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATTTCCTCTTCGTCGTGGACTCTTTCAAGGCTAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGTCACGACGGCGCGGGGCCTGGTTGGGTAGCTGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGCATGTCGTGGTCGGCCTGATGGTGCCGATCACGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCCTCTCGGAGGACGGGGCGTCATCATTGAGTCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGATGCCGGTCAGACGGGTGTACTCCTGAGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACCGAAGGCCCCTCGATCGTCTTGCCTCGCTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAAGGCCTGATCTGCGTCAATGCAGACGACCGCCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAGATTGCGCAGGGGAAAGCCACGGGAGTCATACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAGGAGTCTCCGATTAAGCATGTGATTCCTTCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAAGCAATTCGACCGGATGATTCGCCGCCGGGTGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCGCGGAACGCACCGTCGTGATCGACCGGACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATAGCGGGACTCCACGCTGTTTGACAGTAAAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCCCGGGCGCATGGATGCAATGCCATGCCGCCGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCTTCCCGCACGATCTCTTTCATCCGTGGCCCAAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGTCGAGTTCGACGCCAAGGGGGCTCTGGCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCGATCGCAAAGCCGATGTCCCGCTGCCAGGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCATCACGGCCGAACAGCGGGCCGATCCGAAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGGCTGCCGACCGCGATCGGCAGAAAAAATTGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AACGGCGACGGGGTGACTCCCTCGGTTCCAATCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTGAGACTATTGTCCCCGTACCCCACAGTGAGTGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGACCGAGCCGACGGCAACCGTGGTGTTGTGGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCACGGTGTAGCCCGCATCCCGGTAGGGGCGGCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTAGGGATGGCCGTCTGGAGGGAGCGGCTCGAAAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGTCTTCACGGTCGCCCCTCCCGGCTTTGCCGAGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACCGAAGCATCAAGCGAAGGCTGTTCCGGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACGTTGACTGCGGCGAAGTCCTCGACGTGATGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCACCGTCGCCTTTGACTTCAAATCAAAGAACTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGATCAGCGAGCTGACGGGTAATCCTTGCGGGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGACTCGGGCGAACAGTGCACTCAGTGTGGCGGTTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGGGCATCGACCTCAAGCGGTTCGTGGCCAATCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTGACCTGGTTGGTTCCGGAGCCGTCCGCCAAATA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGGAGTGTTCGACTCCGAGGAGAAAGCCACTGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCAGCGCGACCATCGCGGCGTTGGTCGGAGGCCCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCTTCGGTCTGTGGGATAACCCGATTGTCGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCAACGTATCGTTCGCGGCCAGTTCGAAGTTCGTAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGCTTGAGAGTCGAACCGTCGACGCCAACGATCTCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCCAGGTCGGTCCCGAATCGTGAGCCGAAACGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGCGTCTCCTGGAGCAGAGACTGAATCGCCTCGAGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGGGCGACGAGCGGAGTGAGGTCGACTGACGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGGCTCCCTTGCCGATCGCGTCCTGCATCAGCTTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAAGAACACCTTTCTCCCTCTGGCCGAGAAAGCCCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACTCGGCTTCATGCGATTTCCTCTAACCCTCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATGCGTCGAGCTCGGCCCAAGCCTGGTCCCGCAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAACTTACTCCCGAGCAGCATCGTCGCGCACTGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTGCGAGAGGCAGCGAGCCACGTACTCAGAGGAGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACAAACCGGTCCGCGATCCGATCACCGCACTCGAGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGGTCGATGCCGGCTCGATTGCCCTAGCCCTGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGCGAACACTTCGAGCCAGGAGAGGGTGGGTGGCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTCAGTCTCTCGATTTCTATCGCGGCCCGCTTGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCCGGGGCCTCCTCGAGACCGAAAAGGCTTAAT


>NC_019892|2|2|474123-487675|CRISPRCasFinder
GTGCTCAACGCCTTGCGGCATCACAGAGGTCAGCAC	GGGAATTGTTCGCGCCCAGGCAAATCTCGGGTTGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCGACCGGTAGATCCGGTGGCCATCTAGGTTGAGCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAACGAGGAATCATGAGCGTGGACGGCGTGAAGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTCCCGCGAGATCGGAATGCCGCGCGGGGATCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGAAGCCCCCTCCGACACCGGGCTCCTCTCAAAAAG
GTGCTCAACGCCTTGCGACATCACATTGGTCGGAGC	TTGATATGAGAATGCGTTGTGTTTTTTTTAGTGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTTCCACTCCGGCGAGGGGTCGAGCAAGGCTTCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGAAGTTATCCGCGGTGGGCGGGGCCGGGCGGAAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTCGATACGCTGAATCTCCTGCCTCGCCTCACTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGAGCTGCTTACGGGCGAGCTGCCCCTCTGGGGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCTTGGGGTCGACGGGCTTGACAAGGAACCGCTCGGACAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCAGCGACGGGAGCGTTTGGTCGAGATGGGATCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGATTGCCCCCCCACCCGATGGATCGGGTGGGGG
GGGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTATCACCATCGCCTGGCTTCAGGGTCGCATGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGAAGGAACGCGCGCTCGAGCTTCGCGACACGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGTGTCGGAGACACTCCTAGTTCAGCCGCCAGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAATAGTACGAGTTTGAGGAGGAAGCACGATATCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTTCTATAACTTCGTCAACAAAGACGCCCAGAGCTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGACGTGACTTGGCATAGACTCCGTCATACCTTCGGAAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCCATAGTGGCGGCGGGTTTGGCGAGCAGCACAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCCTCGCCAGAGGACTCGATCGAGAATTGAAG
GTGCTCAACGTCTTGCGGCATCACAGAGGTCGGCAC	ATCACGATACTCGACCTTGGCATTGGCGCAGTCGACAT
GTGCTCAACGCCTTGCAGCATCACAGAGGTCGGCAC	CCTGTGCGTGCGCGTCACGTGTACGTGCGTGCGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTGCGAAGCGGTGTAATAATCGAAGCCATGTTC
GTGCTCAACGCCTTGCGGCATCACAGAGGCCGGCAC	CTTCAATGGCGAAGTCCTCGCCCAGGTCGATGGCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCCTACCGGCCTCTGACTCGGTTCGAGGATCTGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCTGAGCTGCGAGAGCGCCAGGATTGGCATGTTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCCAGCGAACGAGCGAGCAGGTATGCCTGATC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACAACCTGATATGCGAGCAGGCTGTGCTTGCCCATGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGACGACGCGCGGTCCCTCGCGATCAGGTTTGCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTGAACTCTTTGTTGATAGACTTGTCGGCTTTCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCAACGCTGGGATAGAGTTGGGTCTGGTAACGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCAGCGTGACGGTGCCGATCGCTACTTTCTGCTCGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATATCCTCGATTGGGCGGCCGATCTCGGCTATCCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGCGAGGTTGCGTAGGGGTTCTTCACTGGGATAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAAACGACTGTTTTGACTACGGCGACTTGGCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTTGAGCACCGGGTCAGCCCGGATCATGCTGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAAAGGGTCGTGATCCGTGGGGCCGGCGGCGTCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGTGGCTCGTGTCGGCGGAGTATGGAGGTAGGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCGATGGAGAGCGACCAATACACTGCGTCTGAGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAATCGGAGACGGAAAGCAGGTTCCGCGACGGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCCAAGCGATGCCGGTTTGCCGCTTGGAGAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCACAGGTGTCACCGCGCAGGCCGATGGGCAGGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGTACGCGACCGAGGCGAGAGACGGCTACACGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTAGTCGCCATCGGTTTCTAAGTTTCAGCTTACGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTACGACGGCTGAATCCGAAATCTATGGTCGGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCGGCCTTGAGCCGTTCGATCATCGCGGCGAGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTCGTCGAGGTCGACCAGGCTGGCCGAATTGCGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGGCTCACCAGGGCCAGGGCGAGTAGGAGGACGTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCGTTTCCCGGTCCGTCCAGGACGCCACGGATGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCACCCGATCAGGTGTTCAGACCCGGCCCGGGACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGCGGCCAACTCGCTCTTGGCGTCCCGGTAGAATGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGCAACCGCAATCGTGGTTCGAGCTCGGCGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCGGCCTCTCCCCCTCTCTCTGGCTCGCCGTTGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGGACCTGGAAGATATCACCAAGCCTGGATGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCCTGGTGATCGTCACCGGCCCGGGGCAGACGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGGTCCCCGTGACGGCCGAATCCACGTTTGCCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTTTGCCGAGCCGGATGACAATCCCGCCGAAGCCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCGGTGAATGCTCGATTCCGATCCCGTGCCCGACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCATCGTCCGACCAGATTGTTGCCGCGACTTGACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACACCGCAATCACCCAGATCACGACCGGCGCATCGAACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGGGTTTCTACGCGCGGCTCACCGGCTCGGCGAACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCCACCAGACCGTCGCGATCCGAACCGAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCGGGCGGGCTCCGCTTGGATTTCCCGGGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCGAGGAAGTTGGGCCGACGGCCGCCGACGGCTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTTTTTGCGTTCAACTCGTTCTCTTGTTCGTTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTTCGCCAGCTTGTCTTTCGCCTGCTCTGTGATCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTCGGCTTCGGAACGACTATCACGATCTTGCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACGCCATCCGTGATGGGATAAAGCGCAACGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCACCGGCCGGGTCGGGCCCGTCGTTGTCGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAAGCCGCGCGGATCTACCGCAAGGCGATGGAGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGATCGGCAC	ACCGCCGTCATTGATCGTCCAAAATTTAGGCGACAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGCGCGGGTACAAACCGGGCAAGGCATCGGGTGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGTCGGACCTGGCTTATCCACCTCCTGGCCGATCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCCAACTCCGGGCCGGCTCGAGGAGATCGCTTGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCACCGATGAGGGTGTTTGGCCAGCCACCGGCCAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGTAGTGCCGCAGTCCCCGCAAGGGCTGGAGTAACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGACGAAGCTACCCACAGGGGAAGCCATGTCTTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTTCAGGGTGCCGTCCTGGTACATGCGGAAGAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGTCACCGGAAGGCCGGGCAATCTGGCGTGAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGGAAAACTCTCCTTCGAGCGCCTGAGCGGCTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCATGAACGGTAATTGGCTCGTAAATAAGAACGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGAGCTGCCTGGGGGCATTCGAGACCGACGAGAGGTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGTCCTTTCGCAGACATCTTGCGAGCGTAAGTCAAGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCACGGATCCACCCAGCAACCTCGCTCATGCGCACCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGATCCCCGACGAGACGGTGTAAGCCGACGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGCCCCAACCAGGCATGGCAAATCTTGGGGCAGCAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGCTCCCGAAGTCTACCGCGATGGGATGGGCTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTGCTTGCGTAGCCATAACCAGGGCTGTGGGCAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCGACATTCCGGAGCCATCCGGCCCGTTTTATTCGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGACGGCCCAATCTCGGCCGCCCAGGGTCAGGCAAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTCGATCCTCGCGTCACGAGGCGTCGACCAGCGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGGCGACGCACCGCTGCAGGTCCGCCTTTGACA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCTACGACGGCAACGCGCCCGCGACGGCGAACACCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGATCCGGACTTGGTCCTTGAGCAGCTTACGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGGAGAACGCGTGTGTGGTCGGACCGGAATCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGAGTGAGGATCGGGAACGCGAGCAACACCAGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATAATCATCGCGCTGGTCGTTTCGGCGGTCGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGATCGCCTCGAAGATTTGGCGGTGGCGGGCCGCAAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAACGACTCTCGCGGTCAGCCAACTCGGCGTTGGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAGACAGCGCTTTGGCTTCCTGAACCGCTTCGGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTATCGTCGCGGGCCTCGATATCCTTGTTCGTAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACTCCGTTGCGGAGTTCGTCCCTAGGCGACCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGAACGCCATCACTAGATCATTCCAGTTGCCGAAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAACCCATGTTTGCAGAAACACGCGACCTTCTTCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCATCTTCGGCGACTCGGCCGGCACGATCATCGCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGAACAGTTCGGCGGCTGAGGCTGTGTCGTAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGACTTGATCGGCGGCGGAAGCGCGTCCACACCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTCAACCATTGTTCCCCCAGCCACGAACACGACCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTTGGAGAAATCCAGTGAGCAATGGAAGGCAGAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCAGCAACGAGAAGTGGTAGACGTCCAAGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCACGGCCGCGAGACCGAATGTCCTTTCGCAGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGCACTGCACCGCCACACTTCGACGACGCGATCATG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGGTGGGGAGAGGGACGCCCGTGGCGACCGTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCCGCCTCATCGCCGGGTTGTGGTACCCGGCGATC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATTGGTTCATCTGCCTTCACGCCCTCATTCCGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATCTCGCCGTCCTCCCACCCGGTTTCGACCGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTGTCCACGGGGATGCTACCAGGAAGGGTATCACGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGTGGCGCAACGCGGGTCTCCTTCAGCGGGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTGACCCCCAAACGGATCAGCGGTGCGAAGTTCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATACGTGCCGACGATCCCGATGAAGGCCCGCCCGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGGACCGGTCGAGGAGTTTCTCTTGGACGAGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGTAGTTGCCGTTCCGGTCTGCCCTCATGCTCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGCTTACCGGTGTCCAGATGACCGGAGCCCAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCAATTCCTCTGGCTTCACTCCGAGGCCCTTCGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCTCAGGACGGGAGACACCGAAGCCACATCTTCACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAAGTTGCTTGAGCGCACCCTGCCGATCACCGGCCCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGTGCGATCTTGCTGTCCCTGCTGGACACGGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTGCTTGCCTTCATGCTCTATGGACTCCACCAAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGATCATATTCACCGGCCACTCGGTGCCGGCCAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGGCCCGCGAGTGTCGCGCGGACCTCGTCATCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGCTCCGGCACAAGATCGGGCTCGTGATCCTCGACTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGCGGCACCACGAGAGACCGGCAAAGTACGCGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGGTTGAAAGGCGACTTCCACGCATACACTCGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACGAGGGCCGCACTGAAGCTGAGAGAACCTATCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTTCCAAACCCACAAAGGTTTCATGTTCTCGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTTGTTACCGGCAGAGTCCTTATGCTTCTTCATA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAAGAGAGTTGTGGACTCGGCCACAGAAGCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATTTCCTCTTCGTCGTGGACTCTTTCAAGGCTAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGTCACGACGGCGCGGGGCCTGGTTGGGTAGCTGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGCATGTCGTGGTCGGCCTGATGGTGCCGATCACGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCCTCTCGGAGGACGGGGCGTCATCATTGAGTCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGATGCCGGTCAGACGGGTGTACTCCTGAGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACCGAAGGCCCCTCGATCGTCTTGCCTCGCTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAAGGCCTGATCTGCGTCAATGCAGACGACCGCCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAGATTGCGCAGGGGAAAGCCACGGGAGTCATACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAGGAGTCTCCGATTAAGCATGTGATTCCTTCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAAGCAATTCGACCGGATGATTCGCCGCCGGGTGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCGCGGAACGCACCGTCGTGATCGACCGGACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATAGCGGGACTCCACGCTGTTTGACAGTAAAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCCCGGGCGCATGGATGCAATGCCATGCCGCCGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCTTCCCGCACGATCTCTTTCATCCGTGGCCCAAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGTCGAGTTCGACGCCAAGGGGGCTCTGGCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCGATCGCAAAGCCGATGTCCCGCTGCCAGGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCATCACGGCCGAACAGCGGGCCGATCCGAAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGGCTGCCGACCGCGATCGGCAGAAAAAATTGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AACGGCGACGGGGTGACTCCCTCGGTTCCAATCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTGAGACTATTGTCCCCGTACCCCACAGTGAGTGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGACCGAGCCGACGGCAACCGTGGTGTTGTGGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCACGGTGTAGCCCGCATCCCGGTAGGGGCGGCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTAGGGATGGCCGTCTGGAGGGAGCGGCTCGAAAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGTCTTCACGGTCGCCCCTCCCGGCTTTGCCGAGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACCGAAGCATCAAGCGAAGGCTGTTCCGGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACGTTGACTGCGGCGAAGTCCTCGACGTGATGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCACCGTCGCCTTTGACTTCAAATCAAAGAACTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGATCAGCGAGCTGACGGGTAATCCTTGCGGGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGACTCGGGCGAACAGTGCACTCAGTGTGGCGGTTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGGGCATCGACCTCAAGCGGTTCGTGGCCAATCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTGACCTGGTTGGTTCCGGAGCCGTCCGCCAAATA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGGAGTGTTCGACTCCGAGGAGAAAGCCACTGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCAGCGCGACCATCGCGGCGTTGGTCGGAGGCCCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCTTCGGTCTGTGGGATAACCCGATTGTCGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCAACGTATCGTTCGCGGCCAGTTCGAAGTTCGTAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGCTTGAGAGTCGAACCGTCGACGCCAACGATCTCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCCAGGTCGGTCCCGAATCGTGAGCCGAAACGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGCGTCTCCTGGAGCAGAGACTGAATCGCCTCGAGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGGGCGACGAGCGGAGTGAGGTCGACTGACGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGGCTCCCTTGCCGATCGCGTCCTGCATCAGCTTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAAGAACACCTTTCTCCCTCTGGCCGAGAAAGCCCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACTCGGCTTCATGCGATTTCCTCTAACCCTCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATGCGTCGAGCTCGGCCCAAGCCTGGTCCCGCAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAACTTACTCCCGAGCAGCATCGTCGCGCACTGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTGCGAGAGGCAGCGAGCCACGTACTCAGAGGAGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACAAACCGGTCCGCGATCCGATCACCGCACTCGAGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGGTCGATGCCGGCTCGATTGCCCTAGCCCTGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGCGAACACTTCGAGCCAGGAGAGGGTGGGTGGCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTCAGTCTCTCGATTTCTATCGCGGCCCGCTTGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCCGGGGCCTCCTCGAGACCGAAAAGGCTTAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC

>NC_019892|2|1|474123-487675|CRT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCAGCAC	GGGAATTGTTCGCGCCCAGGCAAATCTCGGGTTGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCGACCGGTAGATCCGGTGGCCATCTAGGTTGAGCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAACGAGGAATCATGAGCGTGGACGGCGTGAAGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTCCCGCGAGATCGGAATGCCGCGCGGGGATCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGAAGCCCCCTCCGACACCGGGCTCCTCTCAAAAAG
GTGCTCAACGCCTTGCGACATCACATTGGTCGGAGC	TTGATATGAGAATGCGTTGTGTTTTTTTTAGTGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTTCCACTCCGGCGAGGGGTCGAGCAAGGCTTCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGAAGTTATCCGCGGTGGGCGGGGCCGGGCGGAAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTCGATACGCTGAATCTCCTGCCTCGCCTCACTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGAGCTGCTTACGGGCGAGCTGCCCCTCTGGGGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCTTGGGGTCGACGGGCTTGACAAGGAACCGCTCGGACAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCAGCGACGGGAGCGTTTGGTCGAGATGGGATCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGATTGCCCCCCCACCCGATGGATCGGGTGGGGG
GGGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTATCACCATCGCCTGGCTTCAGGGTCGCATGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGAAGGAACGCGCGCTCGAGCTTCGCGACACGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGTGTCGGAGACACTCCTAGTTCAGCCGCCAGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAATAGTACGAGTTTGAGGAGGAAGCACGATATCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTTCTATAACTTCGTCAACAAAGACGCCCAGAGCTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGACGTGACTTGGCATAGACTCCGTCATACCTTCGGAAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCCATAGTGGCGGCGGGTTTGGCGAGCAGCACAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCCTCGCCAGAGGACTCGATCGAGAATTGAAG
GTGCTCAACGTCTTGCGGCATCACAGAGGTCGGCAC	ATCACGATACTCGACCTTGGCATTGGCGCAGTCGACAT
GTGCTCAACGCCTTGCAGCATCACAGAGGTCGGCAC	CCTGTGCGTGCGCGTCACGTGTACGTGCGTGCGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTGCGAAGCGGTGTAATAATCGAAGCCATGTTC
GTGCTCAACGCCTTGCGGCATCACAGAGGCCGGCAC	CTTCAATGGCGAAGTCCTCGCCCAGGTCGATGGCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCCTACCGGCCTCTGACTCGGTTCGAGGATCTGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCTGAGCTGCGAGAGCGCCAGGATTGGCATGTTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCCAGCGAACGAGCGAGCAGGTATGCCTGATC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACAACCTGATATGCGAGCAGGCTGTGCTTGCCCATGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGACGACGCGCGGTCCCTCGCGATCAGGTTTGCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTGAACTCTTTGTTGATAGACTTGTCGGCTTTCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCAACGCTGGGATAGAGTTGGGTCTGGTAACGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCAGCGTGACGGTGCCGATCGCTACTTTCTGCTCGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATATCCTCGATTGGGCGGCCGATCTCGGCTATCCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGCGAGGTTGCGTAGGGGTTCTTCACTGGGATAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAAACGACTGTTTTGACTACGGCGACTTGGCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTTGAGCACCGGGTCAGCCCGGATCATGCTGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAAAGGGTCGTGATCCGTGGGGCCGGCGGCGTCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGTGGCTCGTGTCGGCGGAGTATGGAGGTAGGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCGATGGAGAGCGACCAATACACTGCGTCTGAGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAATCGGAGACGGAAAGCAGGTTCCGCGACGGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCCAAGCGATGCCGGTTTGCCGCTTGGAGAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCACAGGTGTCACCGCGCAGGCCGATGGGCAGGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGTACGCGACCGAGGCGAGAGACGGCTACACGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTAGTCGCCATCGGTTTCTAAGTTTCAGCTTACGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTACGACGGCTGAATCCGAAATCTATGGTCGGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCGGCCTTGAGCCGTTCGATCATCGCGGCGAGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTCGTCGAGGTCGACCAGGCTGGCCGAATTGCGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGGCTCACCAGGGCCAGGGCGAGTAGGAGGACGTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCGTTTCCCGGTCCGTCCAGGACGCCACGGATGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCACCCGATCAGGTGTTCAGACCCGGCCCGGGACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGCGGCCAACTCGCTCTTGGCGTCCCGGTAGAATGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGCAACCGCAATCGTGGTTCGAGCTCGGCGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCGGCCTCTCCCCCTCTCTCTGGCTCGCCGTTGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGGACCTGGAAGATATCACCAAGCCTGGATGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCCTGGTGATCGTCACCGGCCCGGGGCAGACGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGGTCCCCGTGACGGCCGAATCCACGTTTGCCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTTTGCCGAGCCGGATGACAATCCCGCCGAAGCCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCGGTGAATGCTCGATTCCGATCCCGTGCCCGACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCATCGTCCGACCAGATTGTTGCCGCGACTTGACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACACCGCAATCACCCAGATCACGACCGGCGCATCGAACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGGGTTTCTACGCGCGGCTCACCGGCTCGGCGAACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCCACCAGACCGTCGCGATCCGAACCGAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCGGGCGGGCTCCGCTTGGATTTCCCGGGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCGAGGAAGTTGGGCCGACGGCCGCCGACGGCTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTTTTTGCGTTCAACTCGTTCTCTTGTTCGTTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTTCGCCAGCTTGTCTTTCGCCTGCTCTGTGATCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTCGGCTTCGGAACGACTATCACGATCTTGCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACGCCATCCGTGATGGGATAAAGCGCAACGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCACCGGCCGGGTCGGGCCCGTCGTTGTCGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAAGCCGCGCGGATCTACCGCAAGGCGATGGAGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGATCGGCAC	ACCGCCGTCATTGATCGTCCAAAATTTAGGCGACAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGCGCGGGTACAAACCGGGCAAGGCATCGGGTGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGTCGGACCTGGCTTATCCACCTCCTGGCCGATCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCCAACTCCGGGCCGGCTCGAGGAGATCGCTTGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCACCGATGAGGGTGTTTGGCCAGCCACCGGCCAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGTAGTGCCGCAGTCCCCGCAAGGGCTGGAGTAACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGACGAAGCTACCCACAGGGGAAGCCATGTCTTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTTCAGGGTGCCGTCCTGGTACATGCGGAAGAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGTCACCGGAAGGCCGGGCAATCTGGCGTGAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGGAAAACTCTCCTTCGAGCGCCTGAGCGGCTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCATGAACGGTAATTGGCTCGTAAATAAGAACGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGAGCTGCCTGGGGGCATTCGAGACCGACGAGAGGTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGTCCTTTCGCAGACATCTTGCGAGCGTAAGTCAAGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCACGGATCCACCCAGCAACCTCGCTCATGCGCACCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGATCCCCGACGAGACGGTGTAAGCCGACGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGCCCCAACCAGGCATGGCAAATCTTGGGGCAGCAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGCTCCCGAAGTCTACCGCGATGGGATGGGCTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTGCTTGCGTAGCCATAACCAGGGCTGTGGGCAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCGACATTCCGGAGCCATCCGGCCCGTTTTATTCGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGACGGCCCAATCTCGGCCGCCCAGGGTCAGGCAAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTCGATCCTCGCGTCACGAGGCGTCGACCAGCGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGGCGACGCACCGCTGCAGGTCCGCCTTTGACA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCTACGACGGCAACGCGCCCGCGACGGCGAACACCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGATCCGGACTTGGTCCTTGAGCAGCTTACGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGGAGAACGCGTGTGTGGTCGGACCGGAATCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGAGTGAGGATCGGGAACGCGAGCAACACCAGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATAATCATCGCGCTGGTCGTTTCGGCGGTCGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGATCGCCTCGAAGATTTGGCGGTGGCGGGCCGCAAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAACGACTCTCGCGGTCAGCCAACTCGGCGTTGGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAGACAGCGCTTTGGCTTCCTGAACCGCTTCGGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTATCGTCGCGGGCCTCGATATCCTTGTTCGTAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACTCCGTTGCGGAGTTCGTCCCTAGGCGACCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGAACGCCATCACTAGATCATTCCAGTTGCCGAAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAACCCATGTTTGCAGAAACACGCGACCTTCTTCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCATCTTCGGCGACTCGGCCGGCACGATCATCGCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGAACAGTTCGGCGGCTGAGGCTGTGTCGTAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGACTTGATCGGCGGCGGAAGCGCGTCCACACCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTCAACCATTGTTCCCCCAGCCACGAACACGACCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTTGGAGAAATCCAGTGAGCAATGGAAGGCAGAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCAGCAACGAGAAGTGGTAGACGTCCAAGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCACGGCCGCGAGACCGAATGTCCTTTCGCAGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGCACTGCACCGCCACACTTCGACGACGCGATCATG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGGTGGGGAGAGGGACGCCCGTGGCGACCGTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCCGCCTCATCGCCGGGTTGTGGTACCCGGCGATC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATTGGTTCATCTGCCTTCACGCCCTCATTCCGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATCTCGCCGTCCTCCCACCCGGTTTCGACCGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTGTCCACGGGGATGCTACCAGGAAGGGTATCACGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGTGGCGCAACGCGGGTCTCCTTCAGCGGGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTGACCCCCAAACGGATCAGCGGTGCGAAGTTCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATACGTGCCGACGATCCCGATGAAGGCCCGCCCGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGGACCGGTCGAGGAGTTTCTCTTGGACGAGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGTAGTTGCCGTTCCGGTCTGCCCTCATGCTCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGCTTACCGGTGTCCAGATGACCGGAGCCCAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCAATTCCTCTGGCTTCACTCCGAGGCCCTTCGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCTCAGGACGGGAGACACCGAAGCCACATCTTCACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAAGTTGCTTGAGCGCACCCTGCCGATCACCGGCCCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGTGCGATCTTGCTGTCCCTGCTGGACACGGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTGCTTGCCTTCATGCTCTATGGACTCCACCAAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGATCATATTCACCGGCCACTCGGTGCCGGCCAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGGCCCGCGAGTGTCGCGCGGACCTCGTCATCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGCTCCGGCACAAGATCGGGCTCGTGATCCTCGACTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGCGGCACCACGAGAGACCGGCAAAGTACGCGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGGTTGAAAGGCGACTTCCACGCATACACTCGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACGAGGGCCGCACTGAAGCTGAGAGAACCTATCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTTCCAAACCCACAAAGGTTTCATGTTCTCGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTTGTTACCGGCAGAGTCCTTATGCTTCTTCATA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAAGAGAGTTGTGGACTCGGCCACAGAAGCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATTTCCTCTTCGTCGTGGACTCTTTCAAGGCTAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGTCACGACGGCGCGGGGCCTGGTTGGGTAGCTGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGCATGTCGTGGTCGGCCTGATGGTGCCGATCACGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCCTCTCGGAGGACGGGGCGTCATCATTGAGTCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGATGCCGGTCAGACGGGTGTACTCCTGAGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACCGAAGGCCCCTCGATCGTCTTGCCTCGCTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAAGGCCTGATCTGCGTCAATGCAGACGACCGCCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAGATTGCGCAGGGGAAAGCCACGGGAGTCATACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAGGAGTCTCCGATTAAGCATGTGATTCCTTCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAAGCAATTCGACCGGATGATTCGCCGCCGGGTGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCGCGGAACGCACCGTCGTGATCGACCGGACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATAGCGGGACTCCACGCTGTTTGACAGTAAAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCCCGGGCGCATGGATGCAATGCCATGCCGCCGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCTTCCCGCACGATCTCTTTCATCCGTGGCCCAAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGTCGAGTTCGACGCCAAGGGGGCTCTGGCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCGATCGCAAAGCCGATGTCCCGCTGCCAGGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCATCACGGCCGAACAGCGGGCCGATCCGAAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGGCTGCCGACCGCGATCGGCAGAAAAAATTGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AACGGCGACGGGGTGACTCCCTCGGTTCCAATCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTGAGACTATTGTCCCCGTACCCCACAGTGAGTGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGACCGAGCCGACGGCAACCGTGGTGTTGTGGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCACGGTGTAGCCCGCATCCCGGTAGGGGCGGCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTAGGGATGGCCGTCTGGAGGGAGCGGCTCGAAAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGTCTTCACGGTCGCCCCTCCCGGCTTTGCCGAGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACCGAAGCATCAAGCGAAGGCTGTTCCGGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACGTTGACTGCGGCGAAGTCCTCGACGTGATGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCACCGTCGCCTTTGACTTCAAATCAAAGAACTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGATCAGCGAGCTGACGGGTAATCCTTGCGGGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGACTCGGGCGAACAGTGCACTCAGTGTGGCGGTTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGGGCATCGACCTCAAGCGGTTCGTGGCCAATCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTGACCTGGTTGGTTCCGGAGCCGTCCGCCAAATA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGGAGTGTTCGACTCCGAGGAGAAAGCCACTGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCAGCGCGACCATCGCGGCGTTGGTCGGAGGCCCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCTTCGGTCTGTGGGATAACCCGATTGTCGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCAACGTATCGTTCGCGGCCAGTTCGAAGTTCGTAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGCTTGAGAGTCGAACCGTCGACGCCAACGATCTCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCCAGGTCGGTCCCGAATCGTGAGCCGAAACGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGCGTCTCCTGGAGCAGAGACTGAATCGCCTCGAGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGGGCGACGAGCGGAGTGAGGTCGACTGACGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGGCTCCCTTGCCGATCGCGTCCTGCATCAGCTTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAAGAACACCTTTCTCCCTCTGGCCGAGAAAGCCCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACTCGGCTTCATGCGATTTCCTCTAACCCTCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATGCGTCGAGCTCGGCCCAAGCCTGGTCCCGCAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAACTTACTCCCGAGCAGCATCGTCGCGCACTGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTGCGAGAGGCAGCGAGCCACGTACTCAGAGGAGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACAAACCGGTCCGCGATCCGATCACCGCACTCGAGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGGTCGATGCCGGCTCGATTGCCCTAGCCCTGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGCGAACACTTCGAGCCAGGAGAGGGTGGGTGGCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTCAGTCTCTCGATTTCTATCGCGGCCCGCTTGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCCGGGGCCTCCTCGAGACCGAAAAGGCTTAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC

>NC_019892|2|2|474555-487675|PILER-CR
	GGGAATTGTTCGCGCCCAGGCAAATCTCGGGTTGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCGACCGGTAGATCCGGTGGCCATCTAGGTTGAGCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAACGAGGAATCATGAGCGTGGACGGCGTGAAGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTCCCGCGAGATCGGAATGCCGCGCGGGGATCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCACGGAAGCCCCCTCCGACACCGGGCTCCTCTCAAAAAGGTGCTCAACGCCTTGCGACATCACATTGGTCGGAGCTTGATATGAGAATGCGTTGTGTTTTTTTTAGTGGTGTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTTCCACTCCGGCGAGGGGTCGAGCAAGGCTTCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGAAGTTATCCGCGGTGGGCGGGGCCGGGCGGAAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTCGATACGCTGAATCTCCTGCCTCGCCTCACTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGAGCTGCTTACGGGCGAGCTGCCCCTCTGGGGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCTTGGGGTCGACGGGCTTGACAAGGAACCGCTCGGACAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCAGCGACGGGAGCGTTTGGTCGAGATGGGATCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGATTGCCCCCCCACCCGATGGATCGGGTGGGGG
GGGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTATCACCATCGCCTGGCTTCAGGGTCGCATGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGAAGGAACGCGCGCTCGAGCTTCGCGACACGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGTGTCGGAGACACTCCTAGTTCAGCCGCCAGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAATAGTACGAGTTTGAGGAGGAAGCACGATATCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTTCTATAACTTCGTCAACAAAGACGCCCAGAGCTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGACGTGACTTGGCATAGACTCCGTCATACCTTCGGAAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCCATAGTGGCGGCGGGTTTGGCGAGCAGCACAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCCTCGCCAGAGGACTCGATCGAGAATTGAAG
GTGCTCAACGTCTTGCGGCATCACAGAGGTCGGCAC	ATCACGATACTCGACCTTGGCATTGGCGCAGTCGACAT
GTGCTCAACGCCTTGCAGCATCACAGAGGTCGGCAC	CCTGTGCGTGCGCGTCACGTGTACGTGCGTGCGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTGCGAAGCGGTGTAATAATCGAAGCCATGTTC
GTGCTCAACGCCTTGCGGCATCACAGAGGCCGGCAC	CTTCAATGGCGAAGTCCTCGCCCAGGTCGATGGCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCCTACCGGCCTCTGACTCGGTTCGAGGATCTGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCTGAGCTGCGAGAGCGCCAGGATTGGCATGTTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCCAGCGAACGAGCGAGCAGGTATGCCTGATC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACAACCTGATATGCGAGCAGGCTGTGCTTGCCCATGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGACGACGCGCGGTCCCTCGCGATCAGGTTTGCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTGAACTCTTTGTTGATAGACTTGTCGGCTTTCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCAACGCTGGGATAGAGTTGGGTCTGGTAACGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCAGCGTGACGGTGCCGATCGCTACTTTCTGCTCGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATATCCTCGATTGGGCGGCCGATCTCGGCTATCCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGCGAGGTTGCGTAGGGGTTCTTCACTGGGATAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAAACGACTGTTTTGACTACGGCGACTTGGCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTTGAGCACCGGGTCAGCCCGGATCATGCTGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAAAGGGTCGTGATCCGTGGGGCCGGCGGCGTCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGTGGCTCGTGTCGGCGGAGTATGGAGGTAGGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCGATGGAGAGCGACCAATACACTGCGTCTGAGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAATCGGAGACGGAAAGCAGGTTCCGCGACGGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCCAAGCGATGCCGGTTTGCCGCTTGGAGAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCACAGGTGTCACCGCGCAGGCCGATGGGCAGGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGTACGCGACCGAGGCGAGAGACGGCTACACGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTAGTCGCCATCGGTTTCTAAGTTTCAGCTTACGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTACGACGGCTGAATCCGAAATCTATGGTCGGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCGGCCTTGAGCCGTTCGATCATCGCGGCGAGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTCGTCGAGGTCGACCAGGCTGGCCGAATTGCGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGGCTCACCAGGGCCAGGGCGAGTAGGAGGACGTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCGTTTCCCGGTCCGTCCAGGACGCCACGGATGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCACCCGATCAGGTGTTCAGACCCGGCCCGGGACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGCGGCCAACTCGCTCTTGGCGTCCCGGTAGAATGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGCAACCGCAATCGTGGTTCGAGCTCGGCGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCGGCCTCTCCCCCTCTCTCTGGCTCGCCGTTGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGGACCTGGAAGATATCACCAAGCCTGGATGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCCTGGTGATCGTCACCGGCCCGGGGCAGACGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGGTCCCCGTGACGGCCGAATCCACGTTTGCCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTTTGCCGAGCCGGATGACAATCCCGCCGAAGCCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCGGTGAATGCTCGATTCCGATCCCGTGCCCGACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCATCGTCCGACCAGATTGTTGCCGCGACTTGACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACACCGCAATCACCCAGATCACGACCGGCGCATCGAACCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGGGTTTCTACGCGCGGCTCACCGGCTCGGCGAACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCCACCAGACCGTCGCGATCCGAACCGAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGCGGGCGGGCTCCGCTTGGATTTCCCGGGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCGAGGAAGTTGGGCCGACGGCCGCCGACGGCTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTTTTTGCGTTCAACTCGTTCTCTTGTTCGTTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTTCGCCAGCTTGTCTTTCGCCTGCTCTGTGATCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTCGGCTTCGGAACGACTATCACGATCTTGCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACGCCATCCGTGATGGGATAAAGCGCAACGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGCACCGGCCGGGTCGGGCCCGTCGTTGTCGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAAGCCGCGCGGATCTACCGCAAGGCGATGGAGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGATCGGCAC	ACCGCCGTCATTGATCGTCCAAAATTTAGGCGACAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGCGCGGGTACAAACCGGGCAAGGCATCGGGTGGAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGTCGGACCTGGCTTATCCACCTCCTGGCCGATCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCCAACTCCGGGCCGGCTCGAGGAGATCGCTTGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCACCGATGAGGGTGTTTGGCCAGCCACCGGCCAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGTAGTGCCGCAGTCCCCGCAAGGGCTGGAGTAACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGGACGAAGCTACCCACAGGGGAAGCCATGTCTTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTTCAGGGTGCCGTCCTGGTACATGCGGAAGAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGTCACCGGAAGGCCGGGCAATCTGGCGTGAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGGAAAACTCTCCTTCGAGCGCCTGAGCGGCTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCATGAACGGTAATTGGCTCGTAAATAAGAACGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGAGCTGCCTGGGGGCATTCGAGACCGACGAGAGGTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGTCCTTTCGCAGACATCTTGCGAGCGTAAGTCAAGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCACGGATCCACCCAGCAACCTCGCTCATGCGCACCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGATCCCCGACGAGACGGTGTAAGCCGACGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGCCCCAACCAGGCATGGCAAATCTTGGGGCAGCAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGCTCCCGAAGTCTACCGCGATGGGATGGGCTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGTGCTTGCGTAGCCATAACCAGGGCTGTGGGCAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCGACATTCCGGAGCCATCCGGCCCGTTTTATTCGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGACGGCCCAATCTCGGCCGCCCAGGGTCAGGCAAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTCGATCCTCGCGTCACGAGGCGTCGACCAGCGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGGCGACGCACCGCTGCAGGTCCGCCTTTGACA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTCTACGACGGCAACGCGCCCGCGACGGCGAACACCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGATCCGGACTTGGTCCTTGAGCAGCTTACGAAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGGAGAACGCGTGTGTGGTCGGACCGGAATCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGAGTGAGGATCGGGAACGCGAGCAACACCAGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATAATCATCGCGCTGGTCGTTTCGGCGGTCGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGATCGCCTCGAAGATTTGGCGGTGGCGGGCCGCAAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAACGACTCTCGCGGTCAGCCAACTCGGCGTTGGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAGACAGCGCTTTGGCTTCCTGAACCGCTTCGGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTATCGTCGCGGGCCTCGATATCCTTGTTCGTAG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACTCCGTTGCGGAGTTCGTCCCTAGGCGACCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGAACGCCATCACTAGATCATTCCAGTTGCCGAAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAACCCATGTTTGCAGAAACACGCGACCTTCTTCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCATCTTCGGCGACTCGGCCGGCACGATCATCGCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGAACAGTTCGGCGGCTGAGGCTGTGTCGTAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGACTTGATCGGCGGCGGAAGCGCGTCCACACCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTCAACCATTGTTCCCCCAGCCACGAACACGACCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TTTGGAGAAATCCAGTGAGCAATGGAAGGCAGAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCAGCAACGAGAAGTGGTAGACGTCCAAGTCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCACGGCCGCGAGACCGAATGTCCTTTCGCAGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGCACTGCACCGCCACACTTCGACGACGCGATCATG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGGTGGGGAGAGGGACGCCCGTGGCGACCGTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCCGCCTCATCGCCGGGTTGTGGTACCCGGCGATC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATTGGTTCATCTGCCTTCACGCCCTCATTCCGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATCTCGCCGTCCTCCCACCCGGTTTCGACCGAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTGTCCACGGGGATGCTACCAGGAAGGGTATCACGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGTGGCGCAACGCGGGTCTCCTTCAGCGGGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTGACCCCCAAACGGATCAGCGGTGCGAAGTTCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATACGTGCCGACGATCCCGATGAAGGCCCGCCCGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTGGACCGGTCGAGGAGTTTCTCTTGGACGAGGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGTAGTTGCCGTTCCGGTCTGCCCTCATGCTCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGCTTACCGGTGTCCAGATGACCGGAGCCCAGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCAATTCCTCTGGCTTCACTCCGAGGCCCTTCGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCTCAGGACGGGAGACACCGAAGCCACATCTTCACT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAAGTTGCTTGAGCGCACCCTGCCGATCACCGGCCCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGTGCGATCTTGCTGTCCCTGCTGGACACGGCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTGCTTGCCTTCATGCTCTATGGACTCCACCAAGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCGATCATATTCACCGGCCACTCGGTGCCGGCCAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGGCCCGCGAGTGTCGCGCGGACCTCGTCATCCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGCTCCGGCACAAGATCGGGCTCGTGATCCTCGACTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGCGGCACCACGAGAGACCGGCAAAGTACGCGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGGTTGAAAGGCGACTTCCACGCATACACTCGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACGAGGGCCGCACTGAAGCTGAGAGAACCTATCGT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCTTCCAAACCCACAAAGGTTTCATGTTCTCGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATTTGTTACCGGCAGAGTCCTTATGCTTCTTCATA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAAGAGAGTTGTGGACTCGGCCACAGAAGCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATTTCCTCTTCGTCGTGGACTCTTTCAAGGCTAGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGTCACGACGGCGCGGGGCCTGGTTGGGTAGCTGTA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGCATGTCGTGGTCGGCCTGATGGTGCCGATCACGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCCTCTCGGAGGACGGGGCGTCATCATTGAGTCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCGATGCCGGTCAGACGGGTGTACTCCTGAGCGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACCGAAGGCCCCTCGATCGTCTTGCCTCGCTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAAGGCCTGATCTGCGTCAATGCAGACGACCGCCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAGATTGCGCAGGGGAAAGCCACGGGAGTCATACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGAGGAGTCTCCGATTAAGCATGTGATTCCTTCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CAAGCAATTCGACCGGATGATTCGCCGCCGGGTGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATCGCGGAACGCACCGTCGTGATCGACCGGACC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CATAGCGGGACTCCACGCTGTTTGACAGTAAAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCCCGGGCGCATGGATGCAATGCCATGCCGCCGAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCCTTCCCGCACGATCTCTTTCATCCGTGGCCCAAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGGTCGAGTTCGACGCCAAGGGGGCTCTGGCTG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCGATCGCAAAGCCGATGTCCCGCTGCCAGGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GATCATCACGGCCGAACAGCGGGCCGATCCGAAATT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCAGGCTGCCGACCGCGATCGGCAGAAAAAATTGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AACGGCGACGGGGTGACTCCCTCGGTTCCAATCAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GTGAGACTATTGTCCCCGTACCCCACAGTGAGTGAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CCGACCGAGCCGACGGCAACCGTGGTGTTGTGGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCACGGTGTAGCCCGCATCCCGGTAGGGGCGGCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGTAGGGATGGCCGTCTGGAGGGAGCGGCTCGAAAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACGTCTTCACGGTCGCCCCTCCCGGCTTTGCCGAGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAACCGAAGCATCAAGCGAAGGCTGTTCCGGCCGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACGTTGACTGCGGCGAAGTCCTCGACGTGATGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CACCACCGTCGCCTTTGACTTCAAATCAAAGAACTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCCGATCAGCGAGCTGACGGGTAATCCTTGCGGGTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGACTCGGGCGAACAGTGCACTCAGTGTGGCGGTTT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ATGGGCATCGACCTCAAGCGGTTCGTGGCCAATCC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CTGACCTGGTTGGTTCCGGAGCCGTCCGCCAAATA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAGGAGTGTTCGACTCCGAGGAGAAAGCCACTGCCG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCCAGCGCGACCATCGCGGCGTTGGTCGGAGGCCCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACCTCTTCGGTCTGTGGGATAACCCGATTGTCGCCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCAACGTATCGTTCGCGGCCAGTTCGAAGTTCGTAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAGCTTGAGAGTCGAACCGTCGACGCCAACGATCTCCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GGCCAGGTCGGTCCCGAATCGTGAGCCGAAACGGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	CGCGTCTCCTGGAGCAGAGACTGAATCGCCTCGAGAA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGAGGGCGACGAGCGGAGTGAGGTCGACTGACGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGGCTCCCTTGCCGATCGCGTCCTGCATCAGCTTGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AAAGAACACCTTTCTCCCTCTGGCCGAGAAAGCCCCGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GACTCGGCTTCATGCGATTTCCTCTAACCCTCTC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AATGCGTCGAGCTCGGCCCAAGCCTGGTCCCGCAC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GAACTTACTCCCGAGCAGCATCGTCGCGCACTGGA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTGCGAGAGGCAGCGAGCCACGTACTCAGAGGAGCT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	ACAAACCGGTCCGCGATCCGATCACCGCACTCGAGCA
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	GCGGTCGATGCCGGCTCGATTGCCCTAGCCCTGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TGCGAACACTTCGAGCCAGGAGAGGGTGGGTGGCGG
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	TCTCAGTCTCTCGATTTCTATCGCGGCCCGCTTGGC
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC	AGGCCGGGGCCTCCTCGAGACCGAAAAGGCTTAAT
GTGCTCAACGCCTTGCGGCATCACAGAGGTCGGCAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015243985.1\|467508_468540_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015243999.1\|497527_498292_-\|glucose-1-dehydrogenase	unknown	unknown	gnl\|CDD\|235500
NC_019892.1\|WP_015243984.1\|466178_467381_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340850
NC_019892.1\|WP_015243992.1\|488287_489943_-\|type-I-MYXAN-CRISPR-associated-endonuclease-Cas4/Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|274899
NC_019892.1\|WP_015243998.1\|496097_497159_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_019892.1\|WP_015243989.1\|470909_472292_+\|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|143587
NC_019892.1\|WP_015243988.1\|469654_470611_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_019892.1\|WP_015243991.1\|487932_488232_-\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
NC_019892.1\|WP_015243994.1\|490681_491623_-\|DevR-family-CRISPR-associated-autoregulator	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NC_019892.1\|WP_015243997.1\|495454_496084_-\|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6	cas6	cd09703_cas6_CAS-I:CAS-III	gnl\|CDD\|370559
NC_019892.1\|WP_015243990.1\|472576_473938_-\|transposase	unknown	unknown	unknown
NC_019892.1\|WP_015244001.1\|498551_500480_-\|exo-alpha-sialidase	unknown	unknown	gnl\|CDD\|271234
NC_019892.1\|WP_015243983.1\|465084_466182_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133005
NC_019892.1\|WP_015243993.1\|490048_490678_-\|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	cas5	cd09688_cas5_CAS-I-B	gnl\|CDD\|187819
NC_019892.1\|WP_015243995.1\|491676_493218_-\|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1	cas8b3	cd09713_cas8b3_CAS-I-B	gnl\|CDD\|132524
NC_019892.1\|WP_044146937.1\|463775_465020_+\|ISAzo13-like-element-ISSiac3-family-transposase	unknown	unknown	gnl\|CDD\|369439
NC_019892.1\|WP_015243986.1\|468650_469118_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015243996.1\|493205_495458_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|273707
NC_019892.1\|WP_015243980.1\|461498_462974_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133029
NC_019892.1\|WP_154673915.1\|469282_469540_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015243985.1\|467508_468540_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	8.55133e-47
NC_019892.1\|WP_015243999.1\|497527_498292_-\|glucose-1-dehydrogenase	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	2.58824e-74
NC_019892.1\|WP_015243984.1\|466178_467381_+\|glycosyltransferase	gnl\|CDD\|340850	cd03823, GT4_ExpE7-like, glycosyltransferase ExpE7 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).	1.21379e-19
NC_019892.1\|WP_015243992.1\|488287_489943_-\|type-I-MYXAN-CRISPR-associated-endonuclease-Cas4/Cas1	gnl\|CDD\|274899	TIGR03983, hypothetical_protein_LA3181, CRISPR-associated endonuclease Cas1, subtype MYXAN. Members of this protein are the Cas1 endonuclease, or Cas1 domain in Cas4/Cas1 fusion proteins, of the MYXAN subtype of CRISPR/Cas systems. These systems typically feature repeats and spacers each about 36 base pairs in length. Species with this type of CRISPR system include Myxococcus xanthus, Cyanothece sp., Leptospira interrogans, Sorangium cellulosum, Anabaena variabilis ATCC 29413, etc.	1.68219e-161
NC_019892.1\|WP_015243989.1\|470909_472292_+\|carbon-nitrogen-hydrolase-family-protein	gnl\|CDD\|143587	cd07197, nitrilase, Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes. This superfamily (also known as the C-N hydrolase superfamily) contains hydrolases that break carbon-nitrogen bonds; it includes nitrilases, cyanide dihydratases, aliphatic amidases, N-terminal amidases, beta-ureidopropionases, biotinidases, pantotheinase, N-carbamyl-D-amino acid amidohydrolases, the glutaminase domain of glutamine-dependent NAD+ synthetase, apolipoprotein N-acyltransferases, and N-carbamoylputrescine amidohydrolases, among others. These enzymes depend on a Glu-Lys-Cys catalytic triad, and work through a thiol acylenzyme intermediate. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer. These oligomers include dimers, tetramers, hexamers, octamers, tetradecamers, octadecamers, as well as variable length helical arrangements and homo-oligomeric spirals. These proteins have roles in vitamin and co-enzyme metabolism, in detoxifying small molecules, in the synthesis of signaling molecules, and in the post-translational modification of proteins. They are used industrially, as biocatalysts in the fine chemical and pharmaceutical industry, in cyanide remediation, and in the treatment of toxic effluent. This superfamily has been classified previously in the literature, based on global and structure-based sequence analysis, into thirteen different enzyme classes (referred to as 1-13). This hierarchy includes those thirteen classes and a few additional subfamilies. A putative distant relative, the plasmid-borne TraB family, has not been included in the hierarchy.	1.22503e-67
NC_019892.1\|WP_015243988.1\|469654_470611_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.66624e-33
NC_019892.1\|WP_015243994.1\|490681_491623_-\|DevR-family-CRISPR-associated-autoregulator	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	6.51523e-42
NC_019892.1\|WP_015243997.1\|495454_496084_-\|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6	gnl\|CDD\|370559	pfam09559, Cas6, Cas6 Crispr. The Cas6 Crispr family of proteins averaging 140 residues are characterized by having a GhGxxxxxGhG motif, where h indicates a hydrophobic residue, at the C-terminus. The CRISPR-Cas system is possibly a mechanism of defense against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	2.78271e-79
NC_019892.1\|WP_015243991.1\|487932_488232_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	8.04798e-23
NC_019892.1\|WP_015244001.1\|498551_500480_-\|exo-alpha-sialidase	gnl\|CDD\|271234	cd15482, Sialidase_non-viral, Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.	1.03885e-49
NC_019892.1\|WP_015243983.1\|465084_466182_+\|glycosyltransferase	gnl\|CDD\|133005	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide. UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.	2.89816e-48
NC_019892.1\|WP_015243993.1\|490048_490678_-\|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	gnl\|CDD\|187819	cd09688, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	4.98132e-66
NC_019892.1\|WP_015243995.1\|491676_493218_-\|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1	gnl\|CDD\|132524	TIGR03485, hypothetical_protein_L8106_30105, CRISPR-associated protein Cas8a1/Csx13, MYXAN subtype. Members of this family are found among cas (CRISPR-Associated) genes close to CRISPR repeats in Leptospira interrogans (a spirochete), Myxococcus xanthus (a delta-proteobacterium), and Lyngbya sp. PCC 8106 (a cyanobacterium). It is found with other cas genes in Anabaena variabilis ATCC 29413. In Lyngbya sp., the protein is split into two tandem genes. This model corresponds to the N-terminal region or upstream gene; the C-terminal region is described by TIGR03486. CRISPR/cas systems are associated with prokaryotic acquired resistance to phage and other exogenous DNA.	1.14796e-50
NC_019892.1\|WP_044146937.1\|463775_465020_+\|ISAzo13-like-element-ISSiac3-family-transposase	gnl\|CDD\|369439	pfam07592, DDE_Tnp_ISAZ013, Rhodopirellula transposase DDE domain. These transposases are found in the planctomycete Rhodopirellula baltica, the cyanobacterium Nostoc, and the Gram-positive bacterium Streptomyces.	0
NC_019892.1\|WP_015243998.1\|496097_497159_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	3.4195e-40
NC_019892.1\|WP_015243996.1\|493205_495458_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	4.81835e-44
NC_019892.1\|WP_015243980.1\|461498_462974_+\|glycosyltransferase	gnl\|CDD\|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	5.32458e-53

>NC_019892.1|WP_015243990.1|472576_473938_-|transposase
MKAARTLQGLQQPQSLIGYVRQFLTPTVWKQARGVVPQRRSAPRWDLQPLVVVMLAMTWATGDSESERFEKARGYYVACHESRRRPGKTFVGFQKAMRRGPMRQLRALAAGVRQQIHARLGSRRIVDGFEPMGCDGSRIECPRTPELERGLGQAGKNDAAPNVWLTAFVHLPTGLLWSWRLGPGTAAEQEHLRHLLATLSPEALIVCDAAYMGFDLVRAILGVKRSFLFRMSSRVDLYTLEVANLEDWTEGPVLYWPNYVQKRGKAPIQCRLIRIPAKGKGKGAVKRDVWLLTDVLDPARLSAATAAKFYRWRWRNEGLFRTYKRVINKVKLAGRTVALVHREAELSLLATQILLAHADLALRTATATDGPVISPRKVLIEIRKEIDAAVKPKVKCYHERLAGCRTGCRKQKSPKATRKWPRRKPHKPPKPPGLHTLTQEQKALLNKHMSAAG
>NC_019892.1|WP_015243989.1|470909_472292_+|carbon-nitrogen-hydrolase-family-protein
MTSFSNRLPWLVLVLVGAGLAVPSANGADEPAVAAVPSGWSSQAPRAEIQPRFTYLPEGGPNHRGSFVIEAAAREGLIGWWQKTFPVQGGRAYKFSAKRKADRIETPRQAAVPRLTWQDARGRSVLRDKPTVASYRPGGRPVAEPEFPADQGAPDAHGWTTVSAVYHVPADAAQALVELSYQWAPGGRVEWSEVALEETSTPSPRLVRLATVHLKPEKGSTNQEKCEQFAAPIAEAARQKADLVVLPETLTYFGRAGSSYADCAEPIPGPSTEYFGRLAKQHDLYIVAGLLERDKPLVYNVAVLIGPDGAIVGKYRKVTLPRGEVTGGITPGHEYPVFTTRFGRVGMMICYDGFFPEVARALSNRGAEVIAWPVWGCNPLLAAARACENHVYLVSSTFTDPKDNWTISAIYGHDGRPLARASEWGTIALTEVDLDEPLYWHSLGDFKAQLPRHRAPTPEE
>NC_019892.1|WP_015243988.1|469654_470611_+|LysR-family-transcriptional-regulator
MPSPTAQRHAYKEISLPQIRCFCDAIRLGSFKAAAKSLGLSHPTVLSQVHALEHHLGVKLVETHARGCRPTADGRLLAVMVAPLVAGFHSLEHTFQEVRGKEVQRLIVATTPRILVDDLPMCVVEFSKNWPNVQIHFEEMRMEEIPEAVETGKADLGLTTTSSPTPGNAWIAFEPAYELEVVLITPKDHPLARRRRVSARDLAEFPLVNAPPGILDPSVSIALKMLNAFQAEPRRVEVANAAAILRYVEMGFGVGLTLRVPSHLADPKFHERSLSRELGRVKVHLVWRNGSLMMPHARAFADLVKDLLNRKTSQPKTA
>NC_019892.1|WP_154673915.1|469282_469540_+|hypothetical-protein
MRQIRGESVSAWFSADALACEPTSQKHRLRGETMISEFVAEPNVNTGDMVISVSTESEQREGSAAKKNEGLIERLRYRRRVFDSI
>NC_019892.1|WP_015243986.1|468650_469118_-|hypothetical-protein
MRTFRQIRSLSGMIVMTSFLIAGCDNGVEDLRAREPISGTVTFEGQPLKEGTIQLQPATQQEGVASGGMVSDGRFEIPRAEGPVPGTYTVAIYAAAGTATSGSAEESSPTAPMPRARKTIASLRGVIPTRYNIETELKAEVKSGGPNTYAFHLKK
>NC_019892.1|WP_015243985.1|467508_468540_-|DUF1559-domain-containing-protein
MHLRRRGFTLIELLVVIAIIAVLIALLLPAVQSAREAARRAQCVNNMKQIGLACMNYESTMEVLPPGIKGSIWGTWMVFVLPYAEQQALYNAWNFLGNNTNTYSGITYGSAFNITVSTSRLNTFTCPSDTPNAPITQTYNIGGKTSWPVTSHNYAANFGNLFVFQNQTGTAGTATVPYLGAPFSDIGSPLATLVSITLAAPIGGYTDVKLSSITDGLSNTMLASEVIQGQGKGGQYNANYDLRGFAWWYGGATFETWLAPNSTLPDQMESGGYCVYPYANNPPCIAAPSVLYITNAARSRHPGGVNTVMADGSVKFVKNSINLATWRALSTTQGSEVISADAY
>NC_019892.1|WP_015243984.1|466178_467381_+|glycosyltransferase
MSLKRLLFASIHGYIDPSSGAAWASRDVLELMAARGVECRAISAGLLSYEREMSVEEILKPLGVPIRKAAPMAGMYPADSLEFDLGGVGVTLVPTASSQAERFVDPSEMNGFLARTARLIDEFRPQVMLTYGGHPASFALMKLARSRDVPVVFHLHNLAYPSRSTFDHATAILVPSEYCRRHYLQQLALESTAIPSPLIPERMVAPVRDPRYVTFINPQLSKGAAVVARIAVELHNRRPEIPLLIVEGRGAADALKAVRLDLSELRNLNRLPNLPNPRAIYRLSRMLLVPSLVRETFGRVAAEGLANGIPVLASDRGALPETLGDAGFVFTLPGRCTPQSVEAPTAHEVAPWVATIERLWDDSAWEVAHQERASVESRRWDPDLVADRYLSFFNAHGRRD
>NC_019892.1|WP_015243983.1|465084_466182_+|glycosyltransferase
MIVRNEEANLPACLASAADLFDEIVIVDTGSTDRTVEIARSFGARVFDFPWVDDFAAARNAALARATGDYAFWLDADDRIEPPHRERLRVLFDGLRSKDSAFVIRCACDADPSGGGATVVDHVRLFPVREDVRWTYRVHEQILPALRKAGITVDWTDAVVRHVGYNDPDLRQKKLRRDAAILELELAECPDDPFVLFNLGQIALESGDPLPAVGYFQRSLAGSAPGDSIICKLHALLARAYQQAGDLDSALAACDAGLAAIPDDVELLFRKGVAHRLRGEPDRAGPCWHRILTLRRPERFASVDEGIFGHVTRRNLAMLSEEQGDRAAAALHWSAVLAERPDDEGARQALGRLGQPMVGSGERPS
>NC_019892.1|WP_044146937.1|463775_465020_+|ISAzo13-like-element-ISSiac3-family-transposase
MYDPLVIAQIQRKFHLLSPEMDERRRRQWAAAEAKELGWGGVSLVAHATGLSRPTISAGMRELERPIAQRTVEGTRVRRPGGGRPTAAKSDPGLMAALESLLDPVTRGDPESPLRWTCKSTRRLAEELSRQNHGVGPRTVATLLHEAGYSLQANRKTREGVAHPDRNAQFEYINASVGRALARGQPAISVDTKKKELVGDFKNGGREWHPQGEPEEVRVHDFLDKTLGKAIPYGVYDMVNDQGWVSVGIDHDTAQFATHSIRRWWQEMGRERFPRATELLITADGGGSNGHRTRLWKVSLQALADDLGLMLSVSHFPPGTSKWNKIEHRLFSFITQNWRGKPLVSHQAIINLIAATTTKSGLIVKAVLDTNHYPLEIKVSDTELAALCLERHEFHGDWNYTIAPRIKKSRFQKL
>NC_019892.1|WP_015243980.1|461498_462974_+|glycosyltransferase
MIGPSPSASCLASVIVPCFDQLAFTRQCVASLARHTRPPWELIVVDNGSTDGTASYLAGISDVASFPVTILTNAENRGFPAGCNQGIAAARGEFVVLLNNDVVVTDGWLDQLVALARVDPAIGMVGPMSNYTCPPQVVLDAKYADLDQMDRFATTWRQQHRGQWVFAEKLSGFCLLIRRRVLEAIGGLDEGFGLGFFDDDDLAMRARSAGFELAVAVDLFVHHHGSRTFAGAGIDAESLLETNRLRFEQKWGIDSSSAQAVSLVSWGNERTATISSGIRPAMDPSHRTWTKLFGVGLPRTGTTSIAMAMLELGLRTAHACFDEALFDVGDAFFDTPVYVDYPELDRRYPGSKFILTWRDPHAWYASFARNLGPYLCRLRTQSDLDPDQLIDRRCYTLAFGADELGEDAFLKRYHDHRRCVEEYFMNRPGDLLVLDLDATIDLWEPICRFLSLPRPDRPFPRINASAIDRWLTLWHPLKLVSRTERVEAEVL
>NC_019892.1|WP_015243991.1|487932_488232_-|CRISPR-associated-endonuclease-Cas2
MNDAKWWLVCYDVHDPTRLRRAAKVLEGSGQRMQESVFRCWMTPSQMHRLRWELTQVLEPNDEVLLIPLCPRCVGGMETTYSAQNHPDWPDSPEPHRII
>NC_019892.1|WP_015243992.1|488287_489943_-|type-I-MYXAN-CRISPR-associated-endonuclease-Cas4/Cas1
MTLPMVDHAPPLRVMSLHALAYCQRLFYLEEVEEIRVASAAVYAGRELHASLEADEEGERTQLELADSGLGLVGKVDALRRRDGSFLPYEHKRGRARRDGKTAMAWPSDRLQVIAYAVLIESATGQAIPEGRIRYHAENVTVRVPIDANARADLEEAVATARRLRETTERPPVAENERLCVRCSLAPVCLPEEVRQADDPEREPTRLFPPDRDGTSLHVVLPGTSVGRSGETLVVKPPDGAPPTKHAIREIDSLLVHGYCQVTTQALNLCVDREIPVHWLTTSGRHTASLTASAGQVQRRLRQYRALADEATCLRLAKSLARAKIESQHRYLLRGSRGDEQARDAMLPNLIPLRSALASLESAPNRDSLRGFEGSAAVGYFRGLDRLLSPTVPELLRYSTRSRRPPLDRFNALLGFGYGLLHTAVMRAILTAGLEPSLGFFHTPRSAAYPLVLDLMELFRVPLWDMVLIGSLNRNQWDPDADFIVTKGKTWLSDTGRRKTIQLFEDRLDETWKHPVIGYSLSYVRTLELEARLLEKEWSGEPGLFARMRLR
>NC_019892.1|WP_015243993.1|490048_490678_-|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS
MIALRVTVPIACFRKGFAREFWETEELPPPATCYGFLLSLVGEQDRRRHVGVRVCPALLGRPERSAVLRTLWRVKKLPLGSPGNTRPDYQEILTNVCLAIWLDSTEEIGTGPTLEDRVHTALDHPERINRFGGLSLGESTHLVDEVTRLSVAPGDRARAYLLNDRGRLSLPVWVDHVGSAKTRYVSGDLVETDVSAPNRDRMPRIEPLS
>NC_019892.1|WP_015243994.1|490681_491623_-|DevR-family-CRISPR-associated-autoregulator
MSLHIYGAVVTHHGTAANNRAETEGNITTLQKLLWFGKVHSSVSAEAIRFAIRRRLAEHEPTNRRWDEDLRMNVWADPIFESWASKTGKPFIDDDILGFMSADAAKEENGPETAPEPDEKKKPRAKGTTKVRRAVLEVTRAISLSPYGGDVTFNAASPGATPSAQKKGSNPVPYGTELHATRYQYGFALTPSALHKPERAAVAIESLCSLGEVAGNHGRFLYDFSPESIVFRVTHDPAPRLLYLFEGGGTTVDAPTLLARVKSGDLPAKELIIAGAFSQTSTAREVAALGATLEPGVRSAARLVCERIAAGEG
>NC_019892.1|WP_015243995.1|491676_493218_-|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1
METLSIDLFAPGMSPLHRAGLGGLATTLQWIDSKVKDDRRPPGEWSIDDRQVELKWPNPEGAKAFLKRLYELAFQIDENGLIHLPGSYGAGIPKLEVLAELQQGMSLTILQFGPNRKSDGLALKSYEIDSQTITIQHQKLTGYTHQSEWEKLVTAKGTLKPQAIISGTIAPGFVQRHVAFPSTTIEQPPGLAIALHFALIGTLSLAIDRKTGVLLVPDVEDLNLFVRRRGLMTPNSATDCRIASPADAALQAQVRLHLIEGAQKLKADRCLAVLFATKSWNEKQKARASVQEVEPDTTALERFDLAMHTLQARIALAKPTKKGEAPVPFWAESVVRPLVAENLAQGRPWYQDFRRLVVSPDGSDDAQKVRQLGYEKKGLQAMVNDHWEDRGEEAIVRSVHEAMFRRFGMIWEEVTGNQTVFNNRKERQMQRWRLAFAGAKTADDFRKALTDLWSRSGSNPVLKSSWREVLPLICDEDRWRLARDLALLALASYERPATAPKEVGSVAGNNTED
>NC_019892.1|WP_015243996.1|493205_495458_-|CRISPR-associated-helicase/endonuclease-Cas3
MTKSILLAKSDGFGRSRQSIREHTELVMKSGKRLVEVTGATQLVAVGLDPLHWLDRFRREIKITALLHDLGKANDHFQEMLIGRATRGQGLRHEAVSFLIARQPEVREWLQSVIDNNRAVELVLWAIAGHHRKFPPSAPPKDCKPEMTVYLSHPDFHDTLALGTRELSLPEPPRFGSDRKLKLISINSSLREFEDAQEDAEIFFKTASDDEKKYVSVLKACLICADVAGSIGRRGSEPMDKWISDAFLNLPQPQQLESVVGKGLKGGELRPFQIQVAEATNRVVFVQAGCGSGKTSAAYLWAAQQAPGKRLFFCYPTTGTATEGFRDYLIDPSLDAELIHGRAEVDMKILGLGDDEPGREAGTKNRQGKASEDSAGALEQWSTPLVSCTVDTVLGLVQNHRRSIYAWPSIAGAALVFDEIHSYDDNLFSALVRFLTDVRGVRCLLMTASLPQPRLQAIREALQGIGETLGGPIDGPEDLQLLKRYRREYSDSPWDRVEDVLSKGKKVLWVVNTVAEAMSLAEHPRAQKLGPTLYHSRFRYVDRVERHKAVISAFANQNTPAFAITTQVAEMSLDLSADLLITHLAPIPSLIQRLGRLNRRARPDRNDGIRPFIIIEPNSHLPYTQEQLQEARAWLALLGNEELSQADLAAHWIAQPVASSDRANHFAWLDGGFATETRHLRDASPGIDVILQRDRVAVESKQSRPEEVRIPMPPPRTGLNWRAWDEVAFCKIPPDDMIIYEEMKGAKWKP
>NC_019892.1|WP_015243997.1|495454_496084_-|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6
MPIIDLSFNIIGTTIPLDHGYSLFSALCRVVPQLHGDTRIGVHPIRGRQTAPGVLSLIDSSRIRLRLPSEEIAPYIAVAGTELELVSHRLQVGIPRVECLTAAASLGSRLVTFRGITDPTLFETNIRRQLEKRKIAGKPSLVVAARATWTGQPMRRVLRVKDKQVIGYSLRIHGLKSEESISIQEEGLGGRRRMGCGVFLPISHTENSI
>NC_019892.1|WP_015243998.1|496097_497159_-|WYL-domain-containing-protein
MMRDEPALRRQWILLRALSAQRFGLTIQEMVTESGVAAKTIRRDLELFRSLGFPLEETVGEFGRKTWKIVSSESQPPLALALNLDEVIALHLGRRLLDPLAGTPIGDAAGQAFRKIRTMFPKMALEYLERFTNFYHIATLAPADYSAQGERLDTLRTAIEDQRAVHILYQSAQATEPAFRDVYPLTLFDQKGALYLIALDPQEDKLKHYKVVRIEDVELTNIPFPRPQNFDPATYMASSFGIYQGDDDILIKVRFAPKVARYVLETKKHQSERLVKQRDGSVVAEYRLSCTNEIRSWILSFGAKAIVLEPESLRREIAEELQTLIVAYATSVSESRQHPFRGEDRHEVPGQFH
>NC_019892.1|WP_015243999.1|497527_498292_-|glucose-1-dehydrogenase
MKLTGKKAIVTGSARGIGRGCALELARAGADIVVNDRERTPEAEAVVAEIEALGRQAVLVEGDAFDHDSCGRITQRAIEALGRLDILISNPAYSRRDDFLNYSPETFRQVIQGTLAGGFSMSQHVVKHMVERGGGGKIVFISSVHARRPFPRSVAYNAGKAGLNHMALTIAGELMPYRINVNLIEPGWIDTPGEHEAFGADVMREAGPALPWGRFGKPEDIGKAAVFLVSDDADYITGSALLVDGGLLLQESHS
>NC_019892.1|WP_015244001.1|498551_500480_-|exo-alpha-sialidase
MPYPIRLIALAGWAIAFGGITHAAAPAPRLELDEATQERCLSLLKGALASDEFWPSMHASEALTLAGHGADVQTALAPKLPKETDDQKRCGLARELARAGDLSYVQVLLDILASPNPHGHIHASESLFKIWQVGDGVKLRQTLTRAEPPKLVMMTAAALVRGGNREALDRVRKYVSDPDGETARIAAWILARTGGASDLRALRAGATRFSDPLTKAYFEHALASLGDADGLKALIRNLGHPDFNVRVYAAEFAPDARAVAAKDALLHLLDDPVLDVRIRAAQALLVLAKPSPSSPTEDISRDVFPATAQNPRYSEGSVLVQRDGSLIYATTEFQGSGSDFAKARIIAVDSTDQGRTWSERRVLQENVGQQNVMSVTLRRLKANNPFDGPIGLFYLVKNSPTDLDVYLRISNDEAKTFGEPRLVTTDPGYHVLNNDRVTVLSTGRILVPIATTEDAVKSPKYASSCYFSDDQGETWKRSRGLIHYPGPGAMEPEVLEQADGRLLMQIRTKVDHIAVSESTDGGESWSEAKSWEIAGPESPATLRRIPSTGNLLLIWNNTLRDGKVSSVRTPLTSALSADEGRTWSFHRNLENDPTKVYAYTSVVFDRGRALLTYYVGDTKTGRISSRFRSVPIAWFSEPSASN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_019892_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_3

784100-784207

Orphan

Consensus_repeat	Method
AGCAGCGGCTACTCGTCCTGCTACAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_3

>merge|NC_019892|3|784100-784207|CRISPRCasFinder
CCCTCCTGCTACTCGTCGTGCTATAGCAGCGGCTACTCGTCCTGCTACAGCAGCAGTGCTTGTTACAGCAGCGCTTGCTACAGCAGCTGCTACTCGTCCTGCTACAGC

>NC_019892|3|3|784100-784207|CRISPRCasFinder
CCCTCCTGCTACTCGTCGTGCTATAGC	AGCGGCTACTCGTCCTGCTACAGCAGCAGTGCTTGTTACAGCAGCGCTTGCTAC
AGCAGCTGCTACTCGTCCTGCTACAGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015244241.1\|790230_790692_+\|DUF1569-domain-containing-protein	unknown	unknown	gnl\|CDD\|369441
NC_019892.1\|WP_157579407.1\|789278_789743_+\|phenylacetaldoxime-dehydratase-family-protein	unknown	unknown	gnl\|CDD\|316352
NC_019892.1\|WP_015244244.1\|793614_793791_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
NC_019892.1\|WP_015244232.1\|781362_782748_-\|DUF393-domain-containing-protein	unknown	unknown	gnl\|CDD\|214802
NC_019892.1\|WP_015244243.1\|792398_793502_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015244230.1\|780368_780818_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870
NC_019892.1\|WP_015244233.1\|782732_783380_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015244226.1\|776355_777429_-\|sulfate/molybdate-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224043
NC_019892.1\|WP_154673951.1\|775384_776038_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015244236.1\|785996_786830_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_019892.1\|WP_015244237.1\|786971_787877_-\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NC_019892.1\|WP_015244227.1\|777492_778383_-\|sulfate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226665
NC_019892.1\|WP_015244242.1\|791340_791664_+\|DUF427-domain-containing-protein	unknown	unknown	gnl\|CDD\|377265
NC_019892.1\|WP_020467687.1\|784899_785760_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133022
NC_019892.1\|WP_015244229.1\|779199_780264_-\|sulfate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270226
NC_019892.1\|WP_015244231.1\|781003_781342_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015244240.1\|789749_790169_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015244224.1\|774201_775278_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015244228.1\|778372_779203_-\|sulfate-ABC-transporter-permease-subunit-CysT	unknown	unknown	gnl\|CDD\|131194
NC_019892.1\|WP_015244238.1\|788302_789103_+\|inositol-monophosphatase	unknown	unknown	gnl\|CDD\|238821

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015244241.1\|790230_790692_+\|DUF1569-domain-containing-protein	gnl\|CDD\|369441	pfam07606, DUF1569, Protein of unknown function (DUF1569). A family of hypothetical proteins identified in Rhodopirellula baltica.	8.02154e-34
NC_019892.1\|WP_157579407.1\|789278_789743_+\|phenylacetaldoxime-dehydratase-family-protein	gnl\|CDD\|316352	pfam13826, DUF4188, Domain of unknown function (DUF4188).	5.26892e-27
NC_019892.1\|WP_015244244.1\|793614_793791_+\|hypothetical-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.000343475
NC_019892.1\|WP_015244232.1\|781362_782748_-\|DUF393-domain-containing-protein	gnl\|CDD\|214802	smart00752, HTTM, Horizontally Transferred TransMembrane Domain. Sequence analysis of vitamin K dependent gamma-carboxylases (VKGC) revealed the presence of a novel domain, HTTM (Horizontally Transferred TransMembrane) in its N-terminus. In contrast to most known domains, HTTM contains four transmembrane regions. Its occurrence in eukaryotes, bacteria and archaea is more likely caused by horizontal gene transfer than by early invention. The conservation of VKGC catalytic sites indicates an enzymatic function also for the other family members.	3.00861e-35
NC_019892.1\|WP_020467687.1\|784899_785760_+\|glycosyltransferase	gnl\|CDD\|133022	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.	5.87573e-62
NC_019892.1\|WP_015244230.1\|780368_780818_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	2.45906e-41
NC_019892.1\|WP_015244226.1\|776355_777429_-\|sulfate/molybdate-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224043	COG1118, CysA, ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism].	4.60725e-150
NC_019892.1\|WP_015244237.1\|786971_787877_-\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	3.3519e-85
NC_019892.1\|WP_015244227.1\|777492_778383_-\|sulfate-ABC-transporter-permease	gnl\|CDD\|226665	COG4208, CysW, ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism].	1.43002e-94
NC_019892.1\|WP_015244242.1\|791340_791664_+\|DUF427-domain-containing-protein	gnl\|CDD\|377265	pfam04248, NTP_transf_9, Domain of unknown function (DUF427). This domain contains a beta-tent fold.	5.90273e-15
NC_019892.1\|WP_015244236.1\|785996_786830_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.04756e-18
NC_019892.1\|WP_015244229.1\|779199_780264_-\|sulfate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270226	cd01005, PBP2_CysP, Substrate binding domain of an active sulfate transporter, a member of the type 2 periplasmic binding fold superfamily. This family contains sulfate binding domain of CysP proteins that serve as initial receptors in the ABC transport of sulfate and thiosulfate in eubacteria. After binding the ligand, CysP interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The CysP proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.68112e-115
NC_019892.1\|WP_015244224.1\|774201_775278_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	6.00948e-43
NC_019892.1\|WP_015244228.1\|778372_779203_-\|sulfate-ABC-transporter-permease-subunit-CysT	gnl\|CDD\|131194	TIGR02139, permease_CysT, sulfate ABC transporter, permease protein CysT. This model represents CysT, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysW (TIGR02140). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions].	2.3685e-92
NC_019892.1\|WP_015244243.1\|792398_793502_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	2.2505e-43
NC_019892.1\|WP_015244238.1\|788302_789103_+\|inositol-monophosphatase	gnl\|CDD\|238821	cd01643, Bacterial_IMPase_like_2, Bacterial family of Mg++ dependent phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate inositol monophosphate or similar substrates.	2.28752e-53

>NC_019892.1|WP_015244233.1|782732_783380_-|hypothetical-protein
MASKVSKFNTGSPEGPNQLHPDRRWPAWARGLASVGLLIHGMAVLAGALASPPSSILEQALVLPFGGYLQRIDQGYTYRYYAPEPPPTPIATATIQYADGRPDETIRLPDRTVRPSLRYQRQLALANHLVVDFETARAMTGDGANSTWARSYARHLAKSRPGCKTITLYTQTHLIPDPERVRQELAAPGHRRVNLDAEEFYTTPERIGEFSCDAF
>NC_019892.1|WP_015244232.1|781362_782748_-|DUF393-domain-containing-protein
MRRFLNSLVEYPASLGSAILRGWNGFFFTPADPTALGLIRLGVGALLFWSLLVYGLDLQAFFGSAGWADPESVRFVNRMQAPAAWSFWFHVPDSLLRPVWVACLVIVAMFTVGLWSRVTAVLAWVIVVSISRRVPVSLFGFDQIVSAWTLYLAFTFASGQAVSLDRFLARYRLARAAVARRRQDGRWVVPSGQPEPSVSANLALRLIQLHLVLIYGMAGLAKLQGPGWWSGTAIWGVLASAEFGQFDLTWLAAYPWLLNLMTHAALAFELGYPILIWVPVLRPLVLLTAVLMHVGIAISAPGLTEFGLAMFAGNLAFVSGPWLRSLVVGDAQPAGRVLYDGACPRCRASMALLTAGDPDRVLEPVDLTAVDVTTVHPNLTKSACIKAMHLVRADGRIDVGYDAVVTLSRWIPLFWPLGLIGSLPILSRGGHRAYNAIAASRPRDVPCTDDVCGIHPPSSVA
>NC_019892.1|WP_015244231.1|781003_781342_-|hypothetical-protein
MMNHIPSRADQGGECPPRRLYLLEPGWRVGQKVGNDREFCYMMAPGQDYYHRVYDGEIVVLRGDERLCMACAERRGLLSFAPKGLGEQLGIVEFAIEESTPEIELGMKEDID
>NC_019892.1|WP_015244230.1|780368_780818_-|Rrf2-family-transcriptional-regulator
MSVSSKCYYAVRAIYALAEHASPEPLKIAEIAEREMIPIRFLEVILGQLKGGGFVQSRRGAEGGYRLLRAADDLTVGEIMRYVDGPIAPVDCVSQSRYKECEFHGECHFFGFWGRVRQAISDVVDKTTFADLVRENRERKRGYVGDWII
>NC_019892.1|WP_015244229.1|779199_780264_-|sulfate-ABC-transporter-substrate-binding-protein
MEQATSSIIGRPRTTARLRGYGLCLVLLVAGCGPVRGAGNSDDTLTIGAYSVVRDAFREKILPGFAAHWKQKTGRLVRFEESYNASGAQSRAIVSGFDADVAVLSLDGDVNRLVKEGLVDKDWKSGPGRGLITRSIVVIGVRPGNPAKISDWDDLARPGVGVLYPDPKTSGGAKWNINAIYGAGLLHDPKTPDPAAARDLLSRVQANVLNMDSSGRQSMATFERGTGDAIVTYENELLLQDKRKGVAAPYVIPAATLQIEGPAAIVETSVKKHGNRAVAVAFLDYLRTEEAQRILTDYGFRPLDSKLDPPGRRPLPPRLFTMKELGGWTKINKEVYDQGGVWDSLFTRSKGRTQ
>NC_019892.1|WP_015244228.1|778372_779203_-|sulfate-ABC-transporter-permease-subunit-CysT
MSRQSPIGTSKSDLVLRGTALTYLGLMVVLPLTALSVRAAEPGLAEFWKQLTNPFAWHALKLTFATALVMVLINAVMGTATAWVLVRYSFPGKGIMNALIDVPFAVPTVVTGLMLVALYGPTSVLGSFLGRHGWGVIYQQPGIVLALLFVSYPFVIRSVQPVLLEMDPAEEEAAATLGAGAFTTFRRVTFPTLWPAILTGTALAFSRALGEFGSVVMVAGNRPLQTKTGPMYIFGEIESGNHHGAMVVSVVLLASSLGILIVLNRMQRHGRPVHGR
>NC_019892.1|WP_015244227.1|777492_778383_-|sulfate-ABC-transporter-permease
MAVDVDLEVDVLPATQTQTTTKTKRDRLPWGRWLLIGLVVGWFAILVLVPALALVRAALAGGFRPFLNALAAPSAREAFRLTLLITLLATVVNTVFGLALAIVLARQNFWGKTLADGIVDLPFAISPIVAGLMLIILYGGKGWIGHWLEPLGIQVVYALPGMVLATTFVTLPFVVREVVPVLREFGVDQEEVAYTLGAGRWRTFWSVTLPSIRWGLAYGVTLTVARSLGEFGALLVVSGNILGRTQTATLYVHDGIESFDIEGAYAASVLLAGVSFVMLIGMEHFRKHVEAREESS
>NC_019892.1|WP_015244226.1|776355_777429_-|sulfate/molybdate-ABC-transporter-ATP-binding-protein
MAIAVRNLTKRFGTFQAVGGVSFEVPAGELVALLGPSGSGKSTILRIIAGLEPADSGDVEITGEDASNLSTQQRGVGFVFQHYALFRHMTIRQNVAFGLQVQKPRPPASEIKARVEELLELVQLLVHADRYPSQLSGGQRQRVALARALATRPKVLLLDEPFGALDAKVRDELRTWLRRLHDEVHVTSLFVTHDQQEAFEVADQVIVLNKGKVEQMGPPQELYEHPATPFVTEFLGSVNVLRAETVLGMELGDEVPLPLDVANSNDNSAVYVRPHDFEITRQSNGRPAWSARIRKLIPLGGLVRLDLTLLDGTTLNVQLTRERCLQLALVDGEDIYVSPKDWKVFHESKRFVENYVI
>NC_019892.1|WP_154673951.1|775384_776038_+|hypothetical-protein
MHNLEDAIGRLYDSFSTVPKPHCIDGCPCCIDRKSVGTLLEKRLRCLTPDDLSSYASSAFLTVGEAADYLYFLPRILDITAREPSWWPRSEVTGRAIRAARPDAWTAGQRAALNDYLGAVVDAAIESGDYDRLDGWICAVASMGFDVRPLLGRIAECPAAVLAYFEENAEGLPRRKLANTFWEPPCPGHDAVVAWFYSAEVAKIPFEAYGYVLTAAE
>NC_019892.1|WP_015244224.1|774201_775278_+|DUF1559-domain-containing-protein
MPRRCASRGFTLIELLVVIAIIAVLIALLLPAVQSAREAARRMQCTNNLKQMGLGLMNYESSNGVFPPATILVPPYSSKQWLFESSWSPAARIAPFMELGPLYNAINFSSTYSDASNTTISYTPIKFLICPSDTGPSVDNPSYGNTPYATTSYGFSVGDWYVWSVNGSALGPVNRSAFGPTYSRSIAQFTDGLSNSLLASEGYIGHLQARDCLTTPSGPSDPTTGAWSPTNVPTPQNSLAALAAVLQACSGSKKYGVPYGHTRWANGAGYYSGFTTAVPPNPKVTGTGFSKGMDWVSVDENNGGPTYASLSASSYHSGGVNALFGDGSVKFIKDSTNPTTWRALGTISSGEVLSADSY
>NC_019892.1|WP_020467687.1|784899_785760_+|glycosyltransferase
MSSSNSNDDHDQLAATPDDDHARREWLIHNLGEPVCRQLGIYRIPDDLVLSVVIPVFNEVHTLHEILRQVRAVPIAKQIILVDDCSTDGTTDLLRKWAETESDLTIVFHEKNRGKGAALRTGFTRATGQIVIVQDADLEYDPAQYPQLVQPIVEGKADVVYGSRFSGESHRVLYFWHTLGNKFLTFLSNMFTNLNLTDMEVCYKVFRREVIQGITLESNRFGFEPEVTAKVARFKVPAIENRPSRRCRIYEIPVSYNGRDYREGKKIGWKDGVQALYCIVRYALAD
>NC_019892.1|WP_015244236.1|785996_786830_+|class-I-SAM-dependent-methyltransferase
MTRIRLLGTALAVVLLLLQASLAAQVTDAPAPQKELEKERDPQDQAKPLRRPRRSSAGPRMYMGRPIADVMSFHGADWLVRDTREQEEQPEAMLDALKIKPGSTVADVGAGVGYTSLKLARRVGSEGIVLATDVQPEMLQMLAANARAAGLKNVRPIRCTSTDTKLPEGKVDLVLMVDVYHECVDPETTLQGLLKALKPGGRLVLVEFRGEDPEVPIKPEHKMTFAQVRRELEPQGFKFKEKFDFLPWQHIIVFEKPVAKDKDKVEEAPARSKADNP
>NC_019892.1|WP_015244237.1|786971_787877_-|RluA-family-pseudouridine-synthase
MPIRLDKLVSERFGLSRRAAQDAVRNGRIDLEGERCDEPGREVETDTPIAFFPNRPKARIVAGRLRVLHEDQHVLIVDKPAGVLTLPTPDRERDTLIERAGRYLTIRHGNPKPFVGVVHRLDKDTSGALALARTHEAVRAFQALFKAHDIERQYLAVVEGLPARASGTIDLPLITDRGDLRRGVGRRPGEGRAAITHYRVIEQFGPVASLVACWLETGRTHQIRIHMAEIGHPVVGDAVYRPRNRPRCKAQFQRQALHAQTLGFRHPLTGQDIMVEATVPHDMDALIVDLRNRYGIRGAGG
>NC_019892.1|WP_015244238.1|788302_789103_+|inositol-monophosphatase
MHDHDPSTLAADLDFVKALAAEASAVALGRFRGVTPQEKTNKSFVTDLDHDLEQFIRERLGQRFPKDRLTGEEYAEAGGGGPRRWSIDPIDGTGNMVHGLPLWAVSIGLLDQGEPVLGVIVIPPLGEMFWAVKGGGAWRDGERLLVRDADTFHVQDNVCVGTNALRAVDPRSLPGRLRDLGSACCEMTFVVAGRLQACTFLGEAAHDVAAGAVIAAEAGCHFGTIDGHVLSPTELVANTPVARPTFVAPPRRLAALMAGARLYSGD
>NC_019892.1|WP_157579407.1|789278_789743_+|phenylacetaldoxime-dehydratase-family-protein
MRRVIATLPESMPELCLIRLGIQVRSVRAVFYAIRLARAIDRSAAEAIVAGAGLLHSERFSLGRKHFGVWQYWRSFEDLEAWSHRPPHSEWWRQAVERMRTKGDLGIYHETFLVPRDRIESIYLDCAPAGLAVFGTTGEPVGSMTASRGRLGRG
>NC_019892.1|WP_015244240.1|789749_790169_+|hypothetical-protein
MGHWGVKSFENDDASDALEAGFEEVHGAVYDDLMDDRSPLTFDQVQQKLANLETLTAALAALVETVGKPFEEWDEVERLAFAGVVVRHAEVEVPIPDEARIRALDWLEHEDIDWDEATVRRLRRDKEIVLLRKAKPPES
>NC_019892.1|WP_015244241.1|790230_790692_+|DUF1569-domain-containing-protein
MAERRTLSFATLDRVMPDVDQLLEGHETLGNWSLGQICNHLATGITGSVDGFPFRTPWIYRKTLGAVRRRRVFQTGRMATGVQLPSRFCPKPGLDARAEAEALRATLRYYAGYQEPLAMHPIFGELTRDEWSRLHAIHCAHHLSFVLPRGSGN
>NC_019892.1|WP_015244242.1|791340_791664_+|DUF427-domain-containing-protein
MGVIIREKNSGTPLAEAVAGRGLLTYEGNLYYDSRLVNHQVLRMSDRTYTCPFKGTCRWVDFVDPQGQLVQDVAWVYADPKTGHEAIKDRFGFYAGSRGATRQDDPR
>NC_019892.1|WP_015244243.1|792398_793502_+|DUF1559-domain-containing-protein
MQNVSRPRRGFTLIELLVVIAIIAVLIALLLPAVQAAREAARRSQCVNNLKQLGLAVHNYADKNNCFPLKDMYPNASNYSCGWSSSWPLAVLPGLEQQAMFDAFNFVFTVQGANWDTGCTNGNGFKNSTVGRAQIATLLCPSENLAVHPDMTNGGMGTMNYYGNAGGPGVISTHSGTIVPNHSGIATTIGSGYGAGGPVTFAAVVDGTSNTALFSEKLYGVGPSGPAFTAGSINAKRGLFPQPAAIAHDTGDPANALSFINKCKSTPASTASASSYSGLSWTSAYPPYTVMNAYTHFGAPNSLACANDNAVWGGPSASLPPTSNHSGGVNVGFADGSVKFIKDSVNLQTWWALGTKYGGEVVSADAY
>NC_019892.1|WP_015244244.1|793614_793791_+|hypothetical-protein
MISLGQRSLFGFLLLTSLVGCSGEPAAPPAPAADAAPAPAPAPASKDPVGAERPITPK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_019892_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_4

2251152-2251243

Orphan

Consensus_repeat	Method
CCCTGCCCCGATCGTGATCGAGTCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_4

>merge|NC_019892|4|2251152-2251243|CRISPRCasFinder
CCCTGCCCCGATCGTGATCGAGTCGATCCCGTCGGTGGGCAAAGAGGTCAGGGTGATCGAGAGTGCCCCTGCCCCGATCGTGATTGAGTCGA

>NC_019892|4|4|2251152-2251243|CRISPRCasFinder
CCCTGCCCCGATCGTGATCGAGTCGA	TCCCGTCGGTGGGCAAAGAGGTCAGGGTGATCGAGAGTGC
CCCTGCCCCGATCGTGATTGAGTCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015245341.1\|2246261_2246792_+\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NC_019892.1\|WP_015245337.1\|2240706_2241009_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015245353.1\|2260241_2261135_+\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|379873
NC_019892.1\|WP_015245335.1\|2238323_2239055_-\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|379187
NC_019892.1\|WP_015245340.1\|2244146_2246030_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NC_019892.1\|WP_173878287.1\|2243145_2243727_-\|response-regulator	unknown	unknown	gnl\|CDD\|381116
NC_019892.1\|WP_015245343.1\|2246862_2248017_-\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NC_019892.1\|WP_015245349.1\|2252996_2253695_+\|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl\|CDD\|223649
NC_019892.1\|WP_015245351.1\|2256437_2258105_+\|Hsp70-family-protein	unknown	unknown	gnl\|CDD\|212667
NC_019892.1\|WP_015245336.1\|2239056_2240226_-\|sulfite-oxidase	unknown	unknown	gnl\|CDD\|239028
NC_019892.1\|WP_015243809.1\|2265914_2267159_-\|ISAzo13-like-element-ISSiac3-family-transposase	unknown	unknown	gnl\|CDD\|369439
NC_019892.1\|WP_015245350.1\|2253758_2256101_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|274782
NC_019892.1\|WP_015245354.1\|2261171_2262842_+\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|369246
NC_019892.1\|WP_015245356.1\|2264985_2265894_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015245345.1\|2249143_2250463_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015245344.1\|2248133_2248823_-\|DUF1080-domain-containing-protein	unknown	unknown	gnl\|CDD\|368908
NC_019892.1\|WP_157579499.1\|2241005_2243012_-\|HDOD-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NC_019892.1\|WP_015245355.1\|2262838_2264944_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|274577
NC_019892.1\|WP_015245347.1\|2251813_2252413_+\|YdeI/OmpD-associated-family-protein	unknown	unknown	gnl\|CDD\|226851
NC_019892.1\|WP_015245352.1\|2258178_2260245_+\|Hsp70-family-protein	unknown	unknown	gnl\|CDD\|212667

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015245341.1\|2246261_2246792_+\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	3.3874e-76
NC_019892.1\|WP_015245351.1\|2256437_2258105_+\|Hsp70-family-protein	gnl\|CDD\|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	5.7223e-130
NC_019892.1\|WP_015245353.1\|2260241_2261135_+\|FHA-domain-containing-protein	gnl\|CDD\|379873	pfam16697, Yop-YscD_cpl, Inner membrane component of T3SS, cytoplasmic domain. Yop-YscD-cpl is the cytoplasmic domain of Yop proteins like YscD from Proteobacteria. YscD forms part of the inner membrane component of the bacterial type III secretion injectosome apparatus.	1.14416e-07
NC_019892.1\|WP_015245335.1\|2238323_2239055_-\|c-type-cytochrome	gnl\|CDD\|379187	pfam13442, Cytochrome_CBB3, Cytochrome C oxidase, cbb3-type, subunit III.	8.27673e-13
NC_019892.1\|WP_015245340.1\|2244146_2246030_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NC_019892.1\|WP_173878287.1\|2243145_2243727_-\|response-regulator	gnl\|CDD\|381116	cd17574, REC_OmpR, phosphoacceptor receiver (REC) domain of OmpR family response regulators. OmpR-like proteins are one of the most widespread transcriptional regulators. OmpR family members contain REC and winged helix-turn-helix (wHTH) DNA-binding output effector domain. They are involved in the control of environmental stress tolerance (such as the oxidative, osmotic and acid stress response), motility, virulence, outer membrane biogenesis and other processes. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	7.31071e-23
NC_019892.1\|WP_015245343.1\|2246862_2248017_-\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	6.14672e-68
NC_019892.1\|WP_015245349.1\|2252996_2253695_+\|nucleotide-exchange-factor-GrpE	gnl\|CDD\|223649	COG0576, GrpE, Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones].	1.37363e-11
NC_019892.1\|WP_015245336.1\|2239056_2240226_-\|sulfite-oxidase	gnl\|CDD\|239028	cd02110, SO_family_Moco_dimer, Subgroup of sulfite oxidase (SO) family molybdopterin binding domains that contains conserved dimerization domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). .	2.60833e-107
NC_019892.1\|WP_015243809.1\|2265914_2267159_-\|ISAzo13-like-element-ISSiac3-family-transposase	gnl\|CDD\|369439	pfam07592, DDE_Tnp_ISAZ013, Rhodopirellula transposase DDE domain. These transposases are found in the planctomycete Rhodopirellula baltica, the cyanobacterium Nostoc, and the Gram-positive bacterium Streptomyces.	0
NC_019892.1\|WP_015245350.1\|2253758_2256101_-\|VWA-domain-containing-protein	gnl\|CDD\|274782	TIGR03788, marine_srt_targ, marine proteobacterial sortase target protein. Members of this protein family are restricted to the Proteobacteria. Each contains a C-terminal sortase-recognition motif, transmembrane domain, and basic residues cluster at the the C-terminus, and is encoded adjacent to a sortase gene. This protein is frequently the only sortase target in its genome, which is as unusual its occurrence in Gram-negative rather than Gram-positive genomes. Many bacteria with this system are marine. In addition to the LPXTG signal, members carry a vault protein inter-alpha-trypsin inhibitor domain (pfam08487) and a von Willebrand factor type A domain (pfam00092).	8.26063e-72
NC_019892.1\|WP_015245354.1\|2261171_2262842_+\|FHA-domain-containing-protein	gnl\|CDD\|369246	pfam07174, FAP, Fibronectin-attachment protein (FAP). This family contains bacterial fibronectin-attachment proteins (FAP). Family members are rich in alanine and proline, are approximately 300 long, and seem to be restricted to mycobacteria. These proteins contain a fibronectin-binding motif that allows mycobacteria to bind to fibronectin in the extracellular matrix.	9.3029e-08
NC_019892.1\|WP_015245344.1\|2248133_2248823_-\|DUF1080-domain-containing-protein	gnl\|CDD\|368908	pfam06439, DUF1080, Domain of Unknown Function (DUF1080). This family has structural similarity to an endo-1,3-1,4-beta glucanase belonging to glycoside hydrolase family 16. However, the structure surrounding the active site differs from that of the endo-1,3-1,4-beta glucanase.	2.37912e-50
NC_019892.1\|WP_157579499.1\|2241005_2243012_-\|HDOD-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.86541e-37
NC_019892.1\|WP_015245355.1\|2262838_2264944_+\|VWA-domain-containing-protein	gnl\|CDD\|274577	TIGR03436, acidobact_VWFA, VWFA-related Acidobacterial domain. Members of this family are bacterial domains that include a region related to the von Willebrand factor type A (VWFA) domain (pfam00092). These domains are restricted to, and have undergone a large paralogous family expansion in, the Acidobacteria, including Solibacter usitatus and Acidobacterium capsulatum ATCC 51196.	2.58156e-27
NC_019892.1\|WP_015245347.1\|2251813_2252413_+\|YdeI/OmpD-associated-family-protein	gnl\|CDD\|226851	COG4430, COG4430, Uncharacterized protein conserved in bacteria [Function unknown].	3.04554e-27
NC_019892.1\|WP_015245352.1\|2258178_2260245_+\|Hsp70-family-protein	gnl\|CDD\|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	2.01849e-135

>NC_019892.1|WP_015245345.1|2249143_2250463_+|hypothetical-protein
MPLDLMTRLDPLRRVRCPFCFERFAACEMHLRCNDHYCKSDFARMIEDPILSHALNGRRVGGAGNSALRSPWWIDPRTDVRRGIRRHFDWMVLPDSLDCPNCRRPTDLRLCPRCHSHLPDSAITLDPGHIAIFGPQSVGKTTFVTVLLHELDHRVGPDRGFVLDPLTDEIRERYEREYHELTYGGSQFGVGEELNGESFRHSHSATPSLETNRGVLQPLVYRLTSRRDSERGGTALLSFFDTAGEDWEMNIEMLRSEARYLGGARGLLFLIDPLRIRSVAHDRRMQLTEKESRVPPADYLTDIRKLATFFRRSPVKVPLAICLNKLDRWGHLLPEGTKLHEWATGVPESAPGPALDQAIHDEVQSALRHWGAAGFLEHVAVTFPNHRFFACSALGDAAQDREDLPQPLPTPLLVERPVLWLLERQGVVAPVDGPRRRGR
>NC_019892.1|WP_015245344.1|2248133_2248823_-|DUF1080-domain-containing-protein
MRIPILVATVSLAWSIPFVVADETKPGDATLGQKAPEGAATLFSGENLNGWVKTDGKTPASWAVDDGILTVKPGDGAIQTEKTFGDFQLHVEFNVPYMPDQKGQARGNSGVYLGGIYELQVLDSYGLKLQDNDCGAIYKQIIPSVNACKPPLQWQTYDVTFHKAVVDGGKVVKKARVTVIHNGIKTINDAEITPTPGGATNKEGEEGPILLQDHGNKVQFRNLWIKPLS
>NC_019892.1|WP_015245343.1|2246862_2248017_-|aminopeptidase-P-family-protein
MLTPTGCATRRSRLWNALPEPCDALVLADPQHLLYFANYVQSPFVFRSADAGALLVLEAGKSTLVADSMVQTFLERATVDEVVAPVWYNGKTSAPHRQGIRVGAAIDFLSRVPGNRIGIERTSVPAAVVEALRAARPDLTLIDLDPIIRPLKRAKDPDEVELLKRSMRAGEAAQAAALAGVKPGMTELDVFLLVQNTAMKSLEEQLIVYGDFATGPRCATDKGGPPIRRTIERGDLCLLDFSVVVHGYRGDFTNTFVVDGEPTPRQREMFEACLSAIEAGEGQLRAGTAARAVDAAVRGRLASLGLAESFTSHSGHGLGLGHPEPPYFVPESTDTLVVGDVVALEPGLYIKGVGGMRFERNYLITKDGFETLSVHDLTISQPGR
>NC_019892.1|WP_015245341.1|2246261_2246792_+|thiol-peroxidase
MAETRKGEVTFKGNPVELVGPKLNVGDKAPDFASVGAGLAVVTLADTAGKARLFNVIPSLDTPVCNIQTRKFSEELQSLGDKVAVYTVSLDLPFAQQRWCTEAKVENLKNLSDAHNHSFGEHYGVLIQGLPIPLLARAVIVVDPDNTIRYIEIVPEIAQEPNYEPALKALKEAAGV
>NC_019892.1|WP_015245340.1|2244146_2246030_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MTRDDPYRYDVIVVGAGHAGLEAALASARMGRRTALLTINCDSVTQMSCNPAIGGVAKGQIVREIDALGGAMGMLTDAAALQFRLLNRGKGPAMHSPRAQCDKKAYQFLGKLTVERQPNLTLRQEMVEALCIDGDRITGLRCRGGAEYRARAVVVTTGTFLQALMHTGETKTAGGRAGDSSAEGLSGSLRSLGFELQRFKTGTPPRLNGRTIDFAKLQEQPGDAEPVAFSFMTDRITQEQCSCHITTTNSAVHDLIRGNIHRAPMYSGQIQSTGPRYCPSIEDKVVRFADRTGHQIFLEPEGRGTLEYYCNGISTSLPRDVQDAIIPLIAGLEHAEIMRYGYAVEYDFAPPTQLHPTLETKNVAGLYFAGQINGTTGYEEAAAQGLIAGINAARAVQGEDPFIVDRSQAYLGVLIDDLVTRGVEEPYRMFTSRAEYRLLLRHDNADLRLTEMGRQIGLVDDARWARFEERTQKISSLRSTLNTTRVEGQSLFQHLRRPPTTWEQLLELSPALASHDDGEAIEQVTIEAKYGGYIERQALEVERFRRLEHKPLPADMDYHAITQLRAEAREKFLRVRPRSLGQAGRISGVNPTDIATLLVYMKQDRSRSPEPASEPVTERESPLDEPA
>NC_019892.1|WP_173878287.1|2243145_2243727_-|response-regulator
MKTVFTTGEAAKICKVSQQTIIRCFDSGQLKGFRVPGSRFRRIPREALYRFMKENSIPTDALESGKRRILIVDDDQAVVDLISDVLANDARFETKVVNNGFGAGMLAKEYHPDLIILDVMLPDINGQAVCELIRKDPTMSDIKIICISGMVEEDKIDELRTSGADDFLHKPLDIDELIRRVCRLLDIETGPTG
>NC_019892.1|WP_157579499.1|2241005_2243012_-|HDOD-domain-containing-protein
MIRRQLERLDRLPLRPTTARLALNAFPEDSAEPSPELLASSRFPTIAESDPGWVLALTRSGTDLEAIKLLEASSWWSATAPSGPAADALNRLWRHSVAVGQAARRLATEAGEPDIDRIARAGLLHGLGLWAVAALEPEWLAEWMAEPDGPRRRAFELQTLGTEASNLGRTLAERWGCDPLVADAAWLHADLLGSMSEASVDSRSLGLIQQAFALAERTPWGLYSVEAREIGGSEPRLRLLIAEVQVRCTPALIEADATAHEERFARSNARLRRQMAELRVEKAANDRFLKAFVDADPAETADGWAERAALSWCEVAGVATARVVWTGPGLESGHEEDPRRAERPATKVLALASRGRPCAEIHLWLDPEGLSESANYASMAPAWQAWAALVADRTQLAAKLESVARGHRGWVDKEEPRVRRAKLDGLAEFAAGAGHELNNPLAVIVGRAQLLLARATEPDTVRSLRAILSQAQRTHRIIRDLMFIGRTPESRPRFCQPDEVVRASLRDIKDEADTRGIRLILKGGEPGPKVWADPDALRHLADALIRNALESTREGDTIQVAVAGGLEEVSWSVKDNGRGITSAEGEHLFDPFFCGRQAGRGLGLGLPRAARIVQQAGGEMRWHSMPGQGTIFQVHIPLLPPPKPPSPTVGAIEVEPAVGRNDPPVLKS
>NC_019892.1|WP_015245337.1|2240706_2241009_+|hypothetical-protein
MKKGRRNLHHAKFARLRRHLEICWDLLRPRRIRTRSARYAAALGEQLGLIERPNCCAWCRRRRLRLQRHHWSYDEPLNVTFLCVECHAIADTMTLEASTA
>NC_019892.1|WP_015245336.1|2239056_2240226_-|sulfite-oxidase
MLEFDRSISRRTALRRTVGGVLVCGSGVASLETHSPVRADEAGLIVRNSRPLDLETPVTALDGWLTPNDQFFVRSHLSTPAIGLAPWSLQVGGLADHPRAWSLNELQKLEQVKIPAVLQCAGNGRAYFRPRLPGVQWEKGAVGHAEWSGVRLVDLLERAGYQRGAGHVHLLGADPPPSPKTPRFLRSIPIERALDPNTLIATHMNGEPLPFLHGGPMRLVVPGWAGNHWLKWLRQISLAKDEAPGTYQQSGYRMPKSPAPPGAVLKPADLVPLTVMNVKSLITAPADGSMLKAGNHEVRGVAWTGDGHVTKVEYAVGPNSPWRPATLQGEPRQGSWRTWKFAWETAQPGKYTIRVRASDSNGDTQPETTAWNKSGYLWNGIDRLTCEVR
>NC_019892.1|WP_015245335.1|2238323_2239055_-|c-type-cytochrome
METYSSPSRPTLSRRASRPALMLGLVGLVVSIPLWSDRSLGSGPTLARRLDDAPAVQTPPGDSQDKDDQEMARLALRDNCLICHSEEMVISQRLTQPQWKAEVEKMVGFGSPLPPDQTDTLITYLSEQYSDSTPSALPARIRYTQALEQVKPTTAEIPPHGSQADQGATLFATHCAACHAPTAQGLDLGPNLVEVATLLRPADFLNVVRTGRHRMPGFQLILNPDQEKDILAWLQSKRYATDP
>NC_019892.1|WP_015245347.1|2251813_2252413_+|YdeI/OmpD-associated-family-protein
MNPIFFETPADFRAWLAENHATAEFLLVGFHKKGTGRPSMTWSESVDEALCFGWIDGVRKGIDAERYTIRFTPRKAGSIWSSVNVRKIQELTELGRMQAAGLAAFQARKEDRSGIYSHEQEDVEMPEPYLGLLRDNTAAWEFYEKQPLSYRKAVNWWVASAKKEETRRKRLDSLMAYSARAERVPQFTWKKAGSSEGGG
>NC_019892.1|WP_015245349.1|2252996_2253695_+|nucleotide-exchange-factor-GrpE
MADELEPENDLILAALPEPLVSEEIAQEIAFVIPAAVYESIDTEDELAQPAEPIADQKESSDSLTLPAIAALGETLHRKLDTLQTLFEREIRAEATREKVVDRLHAELQEYKQGLLLNVLRPIFVDLIQLHDDIGKIAEAQGEGDGNGEASRYLGLMRGFQQGIEDILYRQGVEPYLQEGESFDPRRQRAVATVVTEDAALNKQIAARHRKGFQAGDRVIRAEIVSVYALKK
>NC_019892.1|WP_015245350.1|2253758_2256101_-|VWA-domain-containing-protein
MKPRVGRYLIVIALALAAQPDRAWSQGIMIDRRPNHPIARSYEIRDVTVDAKVRDQVAEVQVSQTFHNPGSTVLESEYYFPLPEEGAIQNFVLMVDGKELPGRLLPKDEARRIYEEIVRTKRDPALLEYMGRGLFRTSVFPIPPGADRKVTMRYTQLCKRDRDLVEFAYPFNTQKFTAKPIQRLTLSLQIQSRDAIKSLYSPTSDTTIRRDGDHDARVLLEQRDVVPKNDFRLVYSLAEGALGATVMSYKPSGSEDGYFLMLASPQVKPTDVKPVPKTVIFVLDRSGSMAGKKIEQARKALQFVLNNLRDDDLFNIVVYDDRVETFQPELQRYTSKTRAEADRFVDNIREGGATNIDAALKSALGMIHDDSRPSYVLFLTDGLPTAGETGEMAIAEGARKANREHARIFAFGVGYDVNSRLLDRLSGGNSGTSEYVKPDDDIESHVSRFYAKMTSPVLTDIRIELTDTDVNRTYPRDLPDLFEGGQLVWVGRYRQAGRSTIRLSGRAGGERRSFEFPAELASTDRGTAFDFVERVWAMRRVGHIIDEIDLRGQNKELIDELVSLSTKYGIMTPYTSFLADESIPLHGGMANTVRAGERLHELEITDGATGVIQRGAKRFYQEAARPSSASGDSFSLPSSAPRAGTPALSTESSTISGRFGGMSLGAGSSGSRRDSNGLQRTRAQGANEPGLFNAEAKEADGRPSVRQVGAKTFYYKNQHWIDSTVKPEDDAKATVIEQFSDAFFRLAESQKTELNQYLTFDEPVTVELDGQIYRFELAKP
>NC_019892.1|WP_015245351.1|2256437_2258105_+|Hsp70-family-protein
MSEGLKRVYGIDLGTTYSAIAYVDEHGKPVIVPNQESERITPSVVLFDGDNIIVGNTAKESAKVEPHRVVSRVKQHMGDPNYVFEHDGQVFSPEDISSFVLRKVVGDAELALGEEKITDVVITCPAYFGTPEREATANAGRLAGLNVRAVLNEPTAAAIAYGLEQGDDQTVLVYDLGGGTFDITMIEIKDRLIRVICTGGDHRLGGTLWDEAIVMYLADQFREQTGLDADPMDDPEVLNDLFLQAERGKKTLTQRDKAPFRVTHAGQQARVELERTKFDEITKHLLDRTIELTREMLADAKVKGHEGFDKIILVGGSTRMPQVRERIVADFAKEPESFDPDESVAKGAALFGLKESLEESVREILAPEGAVANGSANEQSLEAASEEQVAEALDRIEKQLGFTLTGPVRDLVNTKIVNVLSKSLGVVARDDKNKDVVVYLLPRNGEVPMEYSSDFGTDTANQAGVDIRVMAGERDSPEPLDCKDVGTATLNLPPSLPARSPIRVKFAINRDGRLIVTATDLTGGASIDVEFETEAVLNAEEVAERSSALRLLNVS
>NC_019892.1|WP_015245352.1|2258178_2260245_+|Hsp70-family-protein
MASTFVGIDLGTTNSVVAWRNTYGRPEVIANREGQNITPSVVYFGTDPPVVGQEAKEWARLGNDEIASFFKPHMGSPLYQLRFGTRDYNASDLSALVLKRLKEDAEAKLGQVVDRAVITVPAYFADAQRKATIDAGNAAGLEVLRIINEPTAAALAYGLQRTGASETVLIYDLGGGTFDVTVAQITPDEIAVLSTAGDHDLGGKNWDDRIATFLSERFAADTGIDPLDDPVALNEVLVRSEQAKWALSDRTTTRITLQLGTERRSYELARAEFESLTFPLMDRTRRLTEEALEEAKLGWKQLSGVLLVGGSTRMPMVRSYVTQMAGAPPRTGVNVDEVVALGAAIQAAMEVGQSSRDATPQFSLAGARRVHDVMSHSLGTVAISPDGSRYINDIVIRRNLPIPAENHKSYLHATHGGANSKLEVYITQGESEQPLDCTILGKYVCSGIHATDAEVTIDLDMSYDANGVVQVRAVQRDTGQTLAMDVEPVPNDLSWLGRPPESMAEPGRPEPVRVYLLMDVSASMAGFPLVEAQTAAREFLDRCDFTTMEVGLISFSTQVTLQAEATDNSRKVQAAISRLEPDSSTNLTDAIDLAREKLDATDRIRYMVVLTDGYPDAPESAVESAKAAREKGIEIVAIGMGDADLDYLRRIASSEQGSIFAHAGELVKTFGHIARVIAEGGRSLRKIQ
>NC_019892.1|WP_015245353.1|2260241_2261135_+|FHA-domain-containing-protein
MSVAAKPVPLARNRFVNVRQAYDLALAGALGAIFGLYLYVELVRADSVLVRDALAGVAIGGTIGFFLNASGPFRDGAWIKLSRVSTWGALAGAAGGALGLVLGESVIGWFQGGLIGRALSWAVLGLGIGVSQGLADRSRQRLLYGLIGGGLGGLVGGYLFEWLRQSLGQRYNNSLGQGLGIVILGAGLGLFLALVEQVLRRAWVQVISGRQEGRVYLLARKVSAMGLDERAEVGLFGDRAVARRHAEIESTPKGYVLRNHAPSGRTRVNGTVIDDTHILSNGDRIELGQTLLVFRQR
>NC_019892.1|WP_015245354.1|2261171_2262842_+|FHA-domain-containing-protein
MNQSGWSLEVVRGTEVGRSYALDGAATVVGNALNGSPGLDLGHQEGSSPRRMAGRQAQFDLSPQGPVVRDLDSPGGTFVNRQRILPGQALTLQPGDLIQIGGVQLKVVSNVATRPLEPTSGLERPTPPKPVPHPATPPPTSSSKPSPRPTPPSPGSQGSPPRPGTNPTPPNPPRPAPGRPAAPPPTDSTRRAPEPVAPPLPRPSLAKGGVFPVPFVLKSGTSCRTCDDLLTVSAQRWEALRDELTSGRLAAFFATNRLAELAPEANAPGTADERLDAWLAQLPTTRSSLPELDVHPETLTVRAVAGGGVTRQVLAITNTGYRLLRSTLRVEPGAAWIKLTPTFAGKPVITVDRTEVPLEIEIPENLAAPKTGTVVIESNGGSRRVTVRLERLPAPESIPELSSAIYGEGGPDLLELVARQPTGLRLALGTLGGLVLRSLVALGGQLPLGQGATEALPRLLGPVLLFATAGSAIGVALTAKRGEARDLPPAGFAGACVGVLGAAIVVALCRAVEPILGPAPSRSIWGSGILWAVLGAGIAGLSLLVAPPRPATEPES
>NC_019892.1|WP_015245355.1|2262838_2264944_+|VWA-domain-containing-protein
MNLRVLVAASLISLGVGQAQARADDPQADAIAQAIERGVAFLKAQQEPRGHWSFSFNHDHTLGITALAGLALMENGIDRADPSITRASSVVHSLAIRSTQTYDLALAILFLARAQVETRGPDDRLIQRLAARLAAGEQGGMWTYTVPLESVEDDERPRRRSSDLSRRVGEVGDNSNTQFALLGIWAASRHGFDPNASLAAIDSHFRRSPDRRGRWGYVSGAAGTDSMTCAGLMGLAISAARPNLAERQTARARGAALAADPIFANALQAVAKDARKIGQNSDIYYIWSLERVCVALGLRNLDGFDWYETGAHELLRRQMDDGGWPEPAWGRTPNTCLALLFLRKANLAFELDRVLKLPAAPRLDKQADEVPVPEKAKDEPPRTGGEENDVVVTGASDSNFPEISVEFEVKRPDGTYLLDATEKDFKVTEEGQPVVIRKFQSPVTTQAHATTVVLVVDRSRSMEEEDRIGALKRSVSSFLKGLPPGSRVAVVAFGSDVKTICPFTGDPQKVQEAVDGLTPEGATRYYDAVAEALEMLNREQGRRAVLALTDGEDTFSQSATLDSVIVAARRLGLPVHTLGLGTEDEIESDALRRLAVETRGQYYPARQADQLRSIYEQLAERLRSSYSLSYQSDRALPDGTLRPVRIYYRASRKAGETAVFIPGMVVPAGGWPQLFLVLVAGLVVLAALPGWLGRKPKHARP
>NC_019892.1|WP_015245356.1|2264985_2265894_+|hypothetical-protein
MLPPIRYPLPTLVLLVILGLITWRGETMIRPLKSALAERWQRQFEGPPVPNSTEPKVVAGPIIRKALLLHDDVITSDHPAGSPSETIRLRMFVDIYDVWPLSGPPDFYRVGNRRPIGWVNANDLLPWETRLVVHVPDDGSAAADARASNDHRPTTSRPALPVLSWTADSVEVARWDEALPWQAVSGRVPIRLAALRPEDWGVWISRPELLSLLRRTGPNPGEPAKTTRLRAILGRLSDDRPLSAKDQAAAIAFLPAQVFMPEGNLMSILGSNESLARVNENWKPEASWGGVSFQFLPLSALP
>NC_019892.1|WP_015243809.1|2265914_2267159_-|ISAzo13-like-element-ISSiac3-family-transposase
MYDPLVIAQIQRKFHLLSPEMDERRRRQWAAAEAKELGWGGVSLVAHATGLSRPTISAGMRELERPIAQRTVEGTRVRRPGGGRPTAAKSDPGLMAALESLLDPVTRGDPESPLRWTCKSTRRLAEELSRQNHGVGPRTVATLLHEAGYSLQANRKTREGVAHPDRNAQFEYINASVGRALARGQPAISVDTKKKELVGDFKNGGREWHPQGEPEEVRVHDFLDKTLGKAIPYGVYDMVNDQGWVSVGIDHDTAQFATHSIRRWWQEMGRERFPRATELLITADGGGSNGHRTRLWKVSLQALADDLGLMLSVSHFPPGTSKWNKIEHRLFSFITQNWRGKPLVSHQAIINLIAATTTKSGLIVKAVLDTNHYPLEIKVSDTELAALCLERHEFHGDWNYTIAPRIKKSRSQKL

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Crispr_ID: NC_019892_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_5

2459935-2460043

Orphan

Consensus_repeat	Method
GTTCCAACGGCTCCTGGCCGAGGTCGCACTCGACCAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_5

>merge|NC_019892|5|2459935-2460043|CRISPRCasFinder
GTTCCAACGGCTCCTGGCCGAGGTCGCACTCGACCACCTTGCGTCCATGCGAATCTGGTGGAGCAGCTCCAAGTTCCAACGGCTCCTGGCCGAGGTCGCACTCGACCAC

>NC_019892|5|5|2459935-2460043|CRISPRCasFinder
GTTCCAACGGCTCCTGGCCGAGGTCGCACTCGACCAC	CTTGCGTCCATGCGAATCTGGTGGAGCAGCTCCAA
GTTCCAACGGCTCCTGGCCGAGGTCGCACTCGACCAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015245502.1\|2464800_2466786_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|274672
NC_019892.1\|WP_020465599.1\|2457876_2458158_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|315923
NC_019892.1\|WP_015245505.1\|2471956_2472094_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020465597.1\|2462344_2462530_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020465598.1\|2461948_2462344_-\|transposase	unknown	unknown	gnl\|CDD\|315923
NC_019892.1\|WP_020465600.1\|2457296_2457518_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225949
NC_019892.1\|WP_020465596.1\|2462526_2462748_-\|transposase	unknown	unknown	gnl\|CDD\|225949
NC_019892.1\|WP_154673606.1\|2467739_2467889_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015245495.1\|2453949_2454243_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015245501.1\|2463231_2464530_+\|Retron-type-reverse-transcriptase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_019892.1\|WP_015245497.1\|2455942_2456452_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015245504.1\|2471275_2471521_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020465595.1\|2468097_2469063_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020465602.1\|2454894_2455557_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015245499.1\|2458367_2459513_+\|ISAs1-family-transposase	unknown	unknown	gnl\|CDD\|379382
NC_019892.1\|WP_020465603.1\|2454427_2454721_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015245494.1\|2453560_2453806_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015245498.1\|2456528_2456888_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226629
NC_019892.1\|WP_015245496.1\|2455605_2455869_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_168165329.1\|2469076_2469550_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015245502.1\|2464800_2466786_+\|AAA-family-ATPase	gnl\|CDD\|274672	TIGR03600, phage_DnaB, phage replicative helicase, DnaB family, HK022 subfamily. Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions].	1.43048e-11
NC_019892.1\|WP_020465600.1\|2457296_2457518_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225949	COG3415, COG3415, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.85021e-09
NC_019892.1\|WP_020465598.1\|2461948_2462344_-\|transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.81753e-36
NC_019892.1\|WP_015245499.1\|2458367_2459513_+\|ISAs1-family-transposase	gnl\|CDD\|379382	pfam13808, DDE_Tnp_1_assoc, DDE_Tnp_1-associated. This domain is frequently found N-terminal to the transposase, IS family DDE_Tnp_1, pfam01609 and its relatives.	1.10417e-33
NC_019892.1\|WP_015245498.1\|2456528_2456888_+\|hypothetical-protein	gnl\|CDD\|226629	COG4149, ModC, ABC-type molybdate transport system, permease component [Inorganic ion transport and metabolism].	0.00725178
NC_019892.1\|WP_020465599.1\|2457876_2458158_+\|hypothetical-protein	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	4.20967e-06
NC_019892.1\|WP_015245501.1\|2463231_2464530_+\|Retron-type-reverse-transcriptase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	2.62694e-46
NC_019892.1\|WP_020465596.1\|2462526_2462748_-\|transposase	gnl\|CDD\|225949	COG3415, COG3415, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.70124e-06

>NC_019892.1|WP_015245499.1|2458367_2459513_+|ISAs1-family-transposase
MAKIVDVGSIGSYFESLSDPRHTRNRKHLMVDIAVIAVCGVICGYDEPTAIHRWAKNRASWLAEHLALHNGIPSRDCIRRLLMALKPEAFQRCFQAWICDAIPADPKNPRRLIAIDGKACRGSHDEANGLGALHIVSAWAGEEGIALGQGATEAKSNEITAIPQLLEQIDLADTLITIDAMGCQKDIVEQIVTGGGDCVIAVKDNQPKLAAAIQAFFLDHLERDLEDLRYRCHETRDDGHGRIDERSYYLAKVPRDFAPGKDWPWIKAIGYAARITQYADGTESDEVRYYLSSRYLSGKRFGEAVRGHWGIESMHWVLDVNFREDEHRTRERTLGNNLSWLRRFAVTLLKRHPDKDSLRGKMMSCMINTDCLTQVLSLQRV
>NC_019892.1|WP_020465599.1|2457876_2458158_+|hypothetical-protein
MVFEGATATPAFQSDVGQVLVPALHSDDVVIWDNLKPHIAAAVAVVEAGARVVPLPPSSPYMTLIEMDQADSTSSDRWCEPTRAGYYRRRRVA
>NC_019892.1|WP_020465600.1|2457296_2457518_+|helix-turn-helix-domain-containing-protein
MPLFSQDLRRRIIDTVERGEVSLRQIARRFLVNLSLVTRLVRHYRTTGSLDPEPHGGAGNPRWDPHSSSDSAH
>NC_019892.1|WP_015245498.1|2456528_2456888_+|hypothetical-protein
MSKTHRRLRGHRPGRRRTGHGRKPPNGLTARHTTAAGATIPHGYTEGAWGSFYRVILPLRGQDKRLFFNCVSDWGVAAAGLLGAILGFAAMGVLGAFLGLGGAIILCDQAMVRGCYIRR
>NC_019892.1|WP_015245497.1|2455942_2456452_+|hypothetical-protein
MPLRLNVGVSKKLGLPEYSSIGASCNLELEVDSMLIHTDLDGLHEQIRGAFVAARQAVNDELARLQTQAPPAVAPHAGAANRPTQGSGALTNESQARSNGARVGTNGPRSRSAKPSTANQVRAIVAIAQRQHADLEGLLRDEYHVDRPEDLSLNQASAFIDQLKIASDV
>NC_019892.1|WP_015245496.1|2455605_2455869_+|hypothetical-protein
MNTQSEPLESTERAATAVMSPVGAEPSSPGGLASLVQDAESLQATLADAKARACRLIVALRRHRWRERLVNATLASLKALKLQDVAD
>NC_019892.1|WP_020465602.1|2454894_2455557_+|hypothetical-protein
MQLRGEGEIAASDGCQLLLRGGFHFPWNEPLLIRRSPVLSCQALARDRPFQLGKTETHVVLQIGPWTLSLEIQAEWRFPLLAGLIPDTSVATTRLRLDPDDAHFLGEALERLPENDEVNAPATFDLNGKIAVRAGDPALTRITELILSRSAYTGSPVRLCTDRAFLSRAVRLGFGEIEIRDDGSPLVCRNAHRRYLWQPLSKESTIEPVGAMTRIESGLA
>NC_019892.1|WP_020465603.1|2454427_2454721_+|hypothetical-protein
MITITRRQARRLRLVFRRSLLGIAHRGPVPPLILRAEGTQLRGQHRHAALAVECTEAGTYPTRETLTLPLDALAQFEGRDESSVFLETVSPERTVVR
>NC_019892.1|WP_015245495.1|2453949_2454243_+|hypothetical-protein
MTRSQLDGAVAQATGESLLTVRRLGFSLMNCGSNSPDPEDLCLVIDCPFCSRPVPHPDPARDGSPTLAECLACDVYFDYAPAEIYAGQRASSVARSS
>NC_019892.1|WP_015245494.1|2453560_2453806_+|hypothetical-protein
MQLVIDPAGQVHAIYDEDFDLAALGPPVIRRASHVEPGPDGRWHADLAPVAGPVLGPFDRRSEALEAERCWLEAHWLVPQA
>NC_019892.1|WP_020465598.1|2461948_2462344_-|transposase
MVGLDPRRLVFIDECGANTAMTRTHGRAPAGQRVYATTPGRWESITLTSGLRLSGVTVALAFPGATNTAVFETYVEDVLVPELKAGDVVIWDNLKPHKSEEVIEAIEAAGASVVPLPPWSPDLTPIEICQP
>NC_019892.1|WP_020465597.1|2462344_2462530_-|hypothetical-protein
MIRQQPDATLEELRQRLGASCSVMTLSRALRKLGLPRKKKVPRAQEQDRPDVQKRRAEFCE
>NC_019892.1|WP_020465596.1|2462526_2462748_-|transposase
MTPYSQDLRQRILEAVRRGDGSLRQIARRSLVSVSFVTRLLRRHRSTGSLGPRPQAEATRRYSGRRTGSGSGS
>NC_019892.1|WP_015245501.1|2463231_2464530_+|Retron-type-reverse-transcriptase
MYNSLRRRGGSKRPAATHARQGAADSHEGSYRDFLGRHASECAEAARGTRRERTEFASRLLERTADSRNLRLAIDHLIREGGNAPGPNGLQLADLDGPERWSLARAYGEAIRAGIYRPGPHRTTVIPKTSGWGTRMLSIQDVEDRVVQRGIVQLLQPFIDPMFAETSYGYRPGRAREHALAAVETLARSSGQWHWILEDVKDSFDQVPHRRLLDSLERLTPSSGFLTLIETVIRNDTGMGLRQGGSLSPLLLNVYLDGHLDRPWKKVHPDVPLVRVADDLLLLCQDRAQSLLTRDALVRRLRSAGMPLRGTPETSIANLAAGESAIWLGYSLTKGKDGLKPRLAESAWRSLEGHLRHTHDGPNAPIHAVETINGWGDQFGPCYPYRDVPRVHAKIAAIARTFAFEEIPSRHDVRTRWERAYATTGRDPTGRR
>NC_019892.1|WP_015245502.1|2464800_2466786_+|AAA-family-ATPase
MGVASNNTRAARKNSNAIINFCSKRMTHEQIEELVVALLRIRTVRLEAVRLLKPEHFSKSQESYLALLWTQVLVLHPEYADAESIPYHVLYSHCKEEAHGQEGLMTLDQYKQLLDTDREIDPDDPEDLPGMLYHSYKVIKKEQLDTDFGIKRLKRFLKERALNEPIISQIAEASHRGLVLANPNEFIASFRQLQGQVEAIGRASSSLASRQQEFEARLALSRGRKLLGLRTGLDTLDRMLDGLRDVTVLAAPSNTGKTVLVVQLGVGVARHVENDCAVVVISLDMETDDLHARVLSHLSQLPHRVLIKGSPELRGQPEGPHLNKDDSASYKAGRAGMKEIGERFFLYGEDDIGGELTALRLRQIMDEVRKRSGTTRVLLVLDYLQLIETPEEISGDDLAADKYRIAAVREAVKPRPGIPLHERDAALIVSETRKRISNPKQHSPMANDDVMGSARTVYRAGCVMLLSPMADDQMRRVYVISTNNPKGKATHPECEAHREFLKHDQHLSPMTLEVTKGRDGMERGSTFLEFHFQTSTMTPIEPKPDSESANPQGAADSQAVIQRRERVMNALESFPKGQSISLNKIQAMIGELHPNHTPNKGTLKKDLTSLVQMGRVVGVPTDISNGKVIWYCSFEKSACEGFEPGSTVQDTDGQEVGLAVG
>NC_019892.1|WP_154673606.1|2467739_2467889_-|hypothetical-protein
MRTGHPAILLRGHAPTMGIHGGREGVGKVDNAFRAPQPAILRTVVSPGN
>NC_019892.1|WP_020465595.1|2468097_2469063_-|hypothetical-protein
MRWVKVLAPVFFPEPEGFSLDFHPIPFRGDSAALDRHYLPLQGKAGPSVLTFFALEQKSRCLCYANANLTRADQHGELMRFVEFWRKVTGSAPKWLYFDSKVVDYRELSRLNQSAIHFVTIRRRRAAIVRRLKGHPTSAWKKAVIDIPKRCHTQISYIEESVQLRGYEGPIRQVAVTGLGRDRPTLFLSNHFEETPRELIIRYAGRNRIEGGLGVSVNFFHLDCLASEVRLNVDLDAALTVIGNSCYRWLASRLSGFERADPKQLYRRFIETAGTVTTQNDRLTVQLDRQSHNPILREAALDRDPTPIPWLDHRTIEFTYR
>NC_019892.1|WP_168165329.1|2469076_2469550_+|hypothetical-protein
MLVTARAVRVVSGERLLGQDVEANEQAEGFVAVEVVDMAPSLFVEQFQCQQREQRTGGGDHLRVRIPRLSDEPIETEPSQVRQEEEDARDAGVDRAAVREIQCATIGDVRSQGTRSVVAYTGSEGSATPVGEKKGVATPRRQSGRKRLANDFRVEGV
>NC_019892.1|WP_015245504.1|2471275_2471521_-|hypothetical-protein
MTGTLRGMIVRQVIEHLINVTFALIIGDGDFVATAVGTTPTLLEIDTTISLGLGSKRPDAGWHGDHIELLLRGSTRQRKLL
>NC_019892.1|WP_015245505.1|2471956_2472094_-|hypothetical-protein
MRKARKNDTPVEKVAILKRHPIDRVPISDLCNEYQLSPTLFSTWQ

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Crispr_ID: NC_019892_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_6

3563969-3564064

Orphan

Consensus_repeat	Method
ACGGTCGCCCCTCCGGGGCTACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_6

>merge|NC_019892|6|3563969-3564064|CRISPRCasFinder
ACGGTCGCCCCTCCGGGGCTACAACACGTAAACATGTCGAATATTCTCCAGGGGTTTCACCCCTGGCTATGAACGGTCGCCCCTCCGGGGCTGCAA

>NC_019892|6|6|3563969-3564064|CRISPRCasFinder
ACGGTCGCCCCTCCGGGGCTACAA	CACGTAAACATGTCGAATATTCTCCAGGGGTTTCACCCCTGGCTATGA
ACGGTCGCCCCTCCGGGGCTGCAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_020466184.1\|3564074_3565028_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239219
NC_019892.1\|WP_044147578.1\|3569671_3571060_-\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NC_019892.1\|WP_015246280.1\|3556787_3558023_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_019892.1\|WP_015246282.1\|3559236_3559626_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381150
NC_019892.1\|WP_015246296.1\|3583725_3584643_+\|N-acetylmuramic-acid-6-phosphate-etherase	unknown	unknown	gnl\|CDD\|235467
NC_019892.1\|WP_015246285.1\|3561498_3563871_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|350617
NC_019892.1\|WP_015246281.1\|3558145_3559099_+\|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl\|CDD\|224007
NC_019892.1\|WP_015246276.1\|3549630_3551562_-\|malto-oligosyltrehalose-trehalohydrolase	unknown	unknown	gnl\|CDD\|274114
NC_019892.1\|WP_015246277.1\|3551689_3552331_-\|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl\|CDD\|273138
NC_019892.1\|WP_015246278.1\|3553115_3555119_+\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_019892.1\|WP_020466179.1\|3581333_3583685_+\|DUF1343-domain-containing-protein	unknown	unknown	gnl\|CDD\|377768
NC_019892.1\|WP_015246294.1\|3579839_3581333_+\|sodium/solute-symporter	unknown	unknown	gnl\|CDD\|271384
NC_019892.1\|WP_015246284.1\|3560564_3561314_+\|4'-phosphopantetheinyl-transferase-superfamily-protein	unknown	unknown	gnl\|CDD\|225002
NC_019892.1\|WP_015246293.1\|3576755_3579374_-\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_019892.1\|WP_015246291.1\|3571094_3574148_-\|DUF1549-domain-containing-protein	unknown	unknown	gnl\|CDD\|377872
NC_019892.1\|WP_015246279.1\|3555248_3556604_+\|beta-glucosidase	unknown	unknown	gnl\|CDD\|274539
NC_019892.1\|WP_015246292.1\|3574718_3576719_+\|retroviral-like-aspartic-protease-family-protein	unknown	unknown	gnl\|CDD\|379408
NC_019892.1\|WP_015246289.1\|3566573_3569381_-\|DUF1553-domain-containing-protein	unknown	unknown	gnl\|CDD\|377872
NC_019892.1\|WP_015246283.1\|3559764_3560568_+\|thioesterase	unknown	unknown	gnl\|CDD\|225749
NC_019892.1\|WP_015246288.1\|3565083_3566502_-\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_020466184.1\|3564074_3565028_-\|hypothetical-protein	gnl\|CDD\|239219	cd02889, SQCY, Squalene cyclase (SQCY) domain; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization cascade converting linear triterpenes to fused ring compounds. Bacterial SQCY catalyzes the convertion of squalene to hopene or diplopterol. Eukaryotic OSQCY transforms the 2,3-epoxide of squalene to compounds such as, lanosterol (a metabolic precursor of cholesterol and steroid hormones) in mammals and fungi or, cycloartenol in plants. Deletion of a single glycine residue of Alicyclobacillus acidocaldarius SQCY alters its substrate specificity into that of eukaryotic OSQCY. Both enzymes have a second minor domain, which forms an alpha-alpha barrel that is inserted into the major domain. This group also contains SQCY-like archael sequences and some bacterial SQCY's which lack this minor domain.	5.94983e-08
NC_019892.1\|WP_044147578.1\|3569671_3571060_-\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	1.7127e-144
NC_019892.1\|WP_015246280.1\|3556787_3558023_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.36013e-48
NC_019892.1\|WP_015246282.1\|3559236_3559626_+\|hypothetical-protein	gnl\|CDD\|381150	cd19923, REC_CheY_CheY3, phosphoacceptor receiver (REC) domain of chemotaxis response regulator CheY3 and similar CheY family proteins. CheY family chemotaxis response regulators (RRs) comprise about 17% of bacterial RRs and almost half of all RRs in archaea. This subfamily contains Vibrio cholerae CheY3, Escherichia coli CheY, and similar CheY family RRs. CheY proteins control bacterial motility and participate in signaling phosphorelays and in protein-protein interactions. CheY RRs contain only the REC domain with no output/effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.52115e-05
NC_019892.1\|WP_015246296.1\|3583725_3584643_+\|N-acetylmuramic-acid-6-phosphate-etherase	gnl\|CDD\|235467	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed.	2.87141e-148
NC_019892.1\|WP_015246285.1\|3561498_3563871_+\|serine-hydrolase	gnl\|CDD\|350617	cd14840, D-Ala-D-Ala_dipeptidase_Aad, D-Ala-D-Ala dipeptidase (includes Lactobacillus plantarum Aad peptidase). D-Ala-D-Ala dipeptidase (also known as D-alanyl-D-alanine dipeptidase vanX; VanX; EC 3.4.13.22) is a Zn2+-dependent enzyme that mediates resistance to the antibiotic vancomycin in Enterococci and other bacteria (both Gram-positive and Gram-negative). It is part of a gene cluster that affects cell-wall biosynthesis. The operon triggers the termination of peptidoglycan precursors by D-Ala-(R)-lactate instead of D-Ala-D-Ala dipeptides. The enzyme is stereospecific, as L-Ala-L-Ala, D-Ala-L-Ala and L-Ala-D-Ala are not substrates. This subfamily includes Lactobacillus Aad peptidase and belongs in the MEROPS peptidase family M15, subfamily D.	1.49914e-84
NC_019892.1\|WP_015246281.1\|3558145_3559099_+\|sugar-phosphate-isomerase/epimerase	gnl\|CDD\|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	1.45014e-26
NC_019892.1\|WP_015246276.1\|3549630_3551562_-\|malto-oligosyltrehalose-trehalohydrolase	gnl\|CDD\|274114	TIGR02402, Malto-oligosyltrehalose_trehalohydrolase, malto-oligosyltrehalose trehalohydrolase. Members of this family are the trehalose biosynthetic enzyme malto-oligosyltrehalose trehalohydrolase, formally known as 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase (EC 3.2.1.141). It is the TreZ protein of the TreYZ pathway for trehalose biosynthesis, and alternative to the OtsAB system. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NC_019892.1\|WP_015246277.1\|3551689_3552331_-\|pyridoxamine-5'-phosphate-oxidase	gnl\|CDD\|273138	TIGR00558, Pyridoxine/pyridoxamine_5'-phosphate_oxidase, pyridoxamine-phosphate oxidase. This model is similar to Pyridox_oxidase from Pfam but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	9.21234e-116
NC_019892.1\|WP_015246278.1\|3553115_3555119_+\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.13217e-49
NC_019892.1\|WP_020466179.1\|3581333_3583685_+\|DUF1343-domain-containing-protein	gnl\|CDD\|377768	pfam07075, DUF1343, Protein of unknown function (DUF1343). This family consists of several hypothetical bacterial proteins of around 400 residues in length. The function of this family is unknown.	0
NC_019892.1\|WP_015246294.1\|3579839_3581333_+\|sodium/solute-symporter	gnl\|CDD\|271384	cd11493, SLC5sbd_NIS-like_u1, uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain. Proteins belonging to the same subfamily as this uncharacterized subgroup include i) NIS, which transports I-, and other anions including ClO4-, SCN-, and Br-, ii) SMVT, which transports biotin, pantothenic acid and lipoate, and iii) the Na(+)/monocarboxylate cotransporters SMCT1 and 2. SMCT1 is a high-affinity transporter while SMCT2 is a low-affinity transporter. This subgroup belongs to the solute carrier 5 (SLC5) transporter family.	3.51261e-166
NC_019892.1\|WP_015246284.1\|3560564_3561314_+\|4'-phosphopantetheinyl-transferase-superfamily-protein	gnl\|CDD\|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	1.27385e-44
NC_019892.1\|WP_015246293.1\|3576755_3579374_-\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.48666e-108
NC_019892.1\|WP_015246291.1\|3571094_3574148_-\|DUF1549-domain-containing-protein	gnl\|CDD\|377872	pfam07583, PSCyt2, Protein of unknown function (DUF1549). A family of paralogues in the planctomyces.	1.73004e-109
NC_019892.1\|WP_015246279.1\|3555248_3556604_+\|beta-glucosidase	gnl\|CDD\|274539	TIGR03356, BGL, beta-galactosidase.	0
NC_019892.1\|WP_015246292.1\|3574718_3576719_+\|retroviral-like-aspartic-protease-family-protein	gnl\|CDD\|379408	pfam13975, gag-asp_proteas, gag-polyprotein putative aspartyl protease. This family of putative aspartyl proteases is found pre-dominantly in retroviral proteins.	1.64928e-12
NC_019892.1\|WP_015246289.1\|3566573_3569381_-\|DUF1553-domain-containing-protein	gnl\|CDD\|377872	pfam07583, PSCyt2, Protein of unknown function (DUF1549). A family of paralogues in the planctomyces.	3.16484e-108
NC_019892.1\|WP_015246283.1\|3559764_3560568_+\|thioesterase	gnl\|CDD\|225749	COG3208, GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism].	5.36975e-82
NC_019892.1\|WP_015246288.1\|3565083_3566502_-\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	3.5856e-165

>NC_019892.1|WP_015246285.1|3561498_3563871_+|serine-hydrolase
MIRAIAALTLSLLTAIPCATLAEDTVPPREPYAEAAKRLEQWITSEIDQKEIPGLSIALVDDQQVVWARGFGFADPQRRLPASAETIYRVGSVSKLFTDIAVMQLAEQGLLDLDAPVQNYLPEFAPKQTSGKPITLRQLMSHRSGLVRESPVGNYFDPTEPTLVATVKSLNETALVYPPEFKTKYSNAGIAVVGLVLEQVGGESFSQAMERRLLGPLKLDRTRFEPTAEMKPLLAQGVMSTFDGRPFAAPTFALGTAPAGNLYSNVLDLGRFLSTLFADGKGPDGATILKSETLRQMIEPQFSKAGDKTKFGFGFALAELDGHRRIGHGGAVYGFATEVGALPDEKVGVVVIANRDCANALTKRIADTALKLMLAVRESKPLPPLESSSPISPELALSLEGRYASGDKGVDLLARNGKLDLTPREGGSRAELRTAGDQLIVDDLLAYGAKIQPKGDQLIIDGTALTRLAAAKPEPSPDRWAGLIGEYGWDHNVLYIYEKDGKLHALIEWFFSYPLEEVSPDLFRFPDRGLYDGESLKFSRDEKGRAKEVVAAEVRFLRRPIDGEDGATFQIQPLRPVAELRVEALAAKPPREAGEFRAPELVDITTIEPTIKLDIRYASTNNFMGTPLYSSARSFMQRPVAEALKKVHQALKPQGYGILIHDSYRPWYVTKMFWDATPDPSKIFVANPAKGSRHNRGSAIDLTLYDLATGKPVPMVGGYDEFSQRSYPDYPGGTSLQRWHRELLRHAMEKEGFTVNINEWWHFDHKDWSTYPILNIPFEKIEQGPSPAKD
>NC_019892.1|WP_015246284.1|3560564_3561314_+|4'-phosphopantetheinyl-transferase-superfamily-protein
MTHQLRPNDRDETLGPDDVHVWMASLEQGEAEVARLRTLLDEPERKRADRYSFEKGRRQFTVARGLLRILLGRYLRIEPTQVQFAYNAHGKPALAEAHRPNLVRFNISHSGEVALFGFANERELGIDLETIRPDFAADAIAARFFAPAELASIRSLPPEDRTQAFFTCWTRKEAYIKAQGKGLALSLDSFEVSLAPGAPAAVLVTHDDREEAARWSLHELHPGPGYVGALAVAGEGCRVRVRTWQGLTT
>NC_019892.1|WP_015246283.1|3559764_3560568_+|thioesterase
MTFPISHKQGLMQANRATNPWLVRPRPNRLANFRLFCFPFAGGGASLFRLWPAQLPDWVELCAVQLPGRETRLREPIHRRIGPLIDELAEAIGTELDKPFVLFGHSMGALVAFELARELRRRNLPSPRLLIASGRIAPQLRPRRPPIHTLPEAEFREELRLLDGTPQALLDHSELMGLFSPIIRADLAVNATYAYTDEPPLDLPILALGGQTDPWVHQEELEGWRLQTNNAFEREQFLGGHFFLQTATAELLTVLSRSLTTLQGLPA
>NC_019892.1|WP_015246282.1|3559236_3559626_+|hypothetical-protein
MAVPRILSVGQCGYDHGNLTRALAGRLNAQITAADTFDDALSKLRTGNYNLLLVNRVTDLDGSHGLELIQAVKADPLLAGTPTMLVSDLANAQEEAVSLGALPGFGKSAMNDPKTLSRIEASLVRTEGS
>NC_019892.1|WP_015246281.1|3558145_3559099_+|sugar-phosphate-isomerase/epimerase
MTEFSRRGWLATVPAALGAGLTLGAQGSSKARAADDPSASPFGFCFNTSTIQGQKLPISEVVDIVGKAGYQGIEPWIRELDQYVKEGGSLKDLGKRIADHGLSVEDAIGFFAWSVDDEAERRKGLEEAKRNMEMVLSIGGHRIAAPPAGATDRSDLDLKRIAERYRTLLELGDSIGVVPQVEIWGFSKTLGRLSEAAMVAIDSGHPKACILPDVYHLHKGGSSFEGLKLLSGQAFHLFHLNDYPDAPSRENITDAHRVYPGDGVAPLRAVFQTLKAVGYRGMLSLELFNREYWKQDPLLVARTGLEKMREAVRQGLA
>NC_019892.1|WP_015246280.1|3556787_3558023_+|Gfo/Idh/MocA-family-oxidoreductase
MRASKTRREFLETMGQVGAGTLLAASTGLETTRGYAANDTIEVACIGTGGRCRTLMKALANVPNVRIAAVCDIYEPHLEEGRKLADPKAHVSRAYRELLDRKDIDAVLIGSPDHWHVPMTVDACNAGKDVYVEKPLTHDLAEGAAVIKAQNESRKIVQIGTQQRSMPHIMKAKELVDQGRIGRIFKVHLTWNRNTQSRMLKGPLGVDPKQVDWKAFLGSAPEQPFDEYRFRNWRWFWNFGGGLLTDLMVHWIDVAHWFLDLDHPEQAAAIGDQLASKGVWETPDTIQCLLHYPNEIQAYFEGTFSNARNGAMIEFMGTDGTLYIDRGRYEIHPEGGKGKAEELILGTDPHRGRDFYDKPDGELLHLTNWIECVRSRQRPHCPAEAGVSAASAAHLGNRAYRSGQLATWTSA
>NC_019892.1|WP_015246279.1|3555248_3556604_+|beta-glucosidase
MTTPSYRFPKDFVWGAAAASAQIEGAANEDGKGESIWDRFASAGGHIANGDTPETACDHYHRYEADTALMSDLGIPNYRLSIAWPRVIPNGDGPVNPRGLDFYDRLIDTLLAAGITPWATLFHWDLPQALEDRGGWLVRSTAEAFRPYAETVVKRLGDRVKNWFTLNEIPCFIGKGYADGEFAPGRTESARAVNQGYHHALLAHGYALSAVRTYGGPGARVGLVHNHLPPPQIPLIETDEHIAAARAEYERTNGQLMGPLFHGRYPEAFLATAGDDAPHVEVGDLDGIAQPMDYLGLNLYSGDFVRAGRNGLPERLAFPRQFPRGDLPWLNLTPQVLYWGVRHAAEVFGVPSFYITEHGAALADEINADGEIIDLDRREVMRSYLVELHRAAHEGYDVRGYFAWSLLDNFEWAEGYAKRFGIVHVDFETQKRTPKLSAHWYSQVIRENRIL
>NC_019892.1|WP_015246278.1|3553115_3555119_+|serine/threonine-protein-kinase
MPAERPTIASCPHCRAILLRTQQALIHPMGSEREEIERALGPFWFEHSTTRFDGRYHRCLGREPIVFTSGNRKANDEPRDPPDTGHSVYRGPHCEFKTSNLVKRSLLIAAFVASLASFSNAQQHSNAPHHRPSVAAESAADVTQVLEQLSTHQAKTGRRQVDQSVILVGGTTEAGNVLSRTTSATVQPMRGRSWQGMELASGRYQILDILRRAAMGVVYLAHDRNLDSDVVVEVPAFPPIHNHESTARFMRAVRSGARLVHPHLVRITEVGTYADAPFVVAEHRAGGSLRFRRPVGPDGRPTPVAPRSLEQWLPDVSDALDFLHAQNRFSREVSLANILFDENGHASLGGLGMAEAIEEWLDTSSSGASRNHQRLTDPSPILAPEIVAGAPADGQADQYALAATVYELLSGHPPFEGPNLAGLLGEESSIEPPELRQVCPTISQALSSAVHRGLAQDPRHRFPDCRAFAQAVVSAAREPGPILEPQTTEPAVATGTDRTLADLPIIDHRRGPAQASHLVLGIACCSLIVVIGATARRKRSRRTTERQTVISSRNERRAIPKSLPLADSATSEGKARALANATPHGEPGTRALDVRRHATELAGRPHFTQVPALLPAKSTGRELVRLPDLDPLMDRPKTRLADNLLPVASTVPARSASLPQPVRRRAS
>NC_019892.1|WP_015246277.1|3551689_3552331_-|pyridoxamine-5'-phosphate-oxidase
MSMSPLRNEYTKATLDETDLDPDPIRQFQRWFDAALAAKVDEPNAMALATATLEGVPSVRIVLLKGIDPRGFTFHTCYDGRKGRELDANPHAAFVLFWPALERQVRIEGRVERVTGEESDAYFQSRPLESQLGAWASPQSEVVPSRTTFEDRMEEYRTRYADGQSIPRPPNWGGYRVLPHTLEFWQGRPSRLHDRVRYQRDATGLWKMERLAP
>NC_019892.1|WP_015246276.1|3549630_3551562_-|malto-oligosyltrehalose-trehalohydrolase
MTLSGQRLGVEQGRPWRPTLGAWLEEGGAGVRFRVWAPEARSVEVVHLSAQAGESSIALERSDDGTFGGLIRTASAGDRYLYRLDAKGTFPDPASRFQPEGVHAPSAIVDPSAFPWSDQGWRGVKREDLVIHEVHVGTFSPEGTFAGVTDRLPWLVELGVTAIELMPVADFAGSRSWGYDGVDLFAPARCYGAPDDLRRLVDEAHRVGLAVILDVVYNHFGPVGNYAPAFSPYYLSTTHQSAWAACVNLDGAQCTMVREFFIENALHWVHEYHVDGLRLDATHELHDESSRHFLVELSSRVRASAPERELVLIAEDERNLAKMVRPESAGGWGLDSVWADDFHHQIRRLLAGDHEGYYRDYRGSIRDLAETLNQGWYYRGQPSIHLGRPRGTDPQGLAPRSFVICLQNHDQIGNRAFGDRLNPAIDLAAFRAASALLLTAPATPLLFMGQEWAATTPFLYFTDHEEDLGKLVTEGRRQEFRHFLAFVDPEARERIPDPQAVSTFEASRLDWSEPERAPHASILRLYQALLSLRRREPALRSNRRDDAQAFPLDDATLLLLRRSSGDQAILLIVACLHGSAEVRLENGPAFGLPSWAGLEIVLTTEDPRFTVDPQPVQVEPCQGALLIRFLRPGALVLRRKADL
>NC_019892.1|WP_020466184.1|3564074_3565028_-|hypothetical-protein
MVWVVLATLPFGPVVVRAADDPGVARAERRVLTFLATEVPRWSRENHCFSCHNNGDAARALLAAKKRGVTLLPEDALRETLAFLSRPERWDKNGVDAAFSDKRLARLQFANALAAAVDANAIGDRSVLLNAADRLVVDQASDGSWNIDEVALIGSPATYGAPLATALARRTLLTADSPRFSGPIHQAARWLQARPVQNTLDVAAILIGLDPNEVSPDLRVRCLDLIRKGQSSDGGWGPFSNSPPEAFDTAMILLALSRWPAPSNEITPFIQGGRRYLVANQAEDGSWTETTRPTGGESYAQRLSTTGWVALSLLATD
>NC_019892.1|WP_015246288.1|3565083_3566502_-|DUF1501-domain-containing-protein
MRNQGVDPSFSRRDMLRKMGGGFGALGLATVLAGEGSALSRVMADEPAANPLAPRLPHFEPRAKRVIFLFMNGGPSHVDTFDPKPQLTKYHGDKPANQGIKTGRKGGGTLMGSPFSFQKYGQSGIEVSELYPEVGKRIDDICVIRSMRTDVPNHEPALLMMNSGQIQPTRPSMGSWLTYGLGTENQNLPGFVVLCPGKPVVGPQLWSNSFLPGIFQGTHINNASLDPKAVIPNVRNRNLTRSAQRGQLDLLAKMNGEHLEGRGRDPQLEARIESLEMAFRMQFEAQDAFDISQESAATRALYGKGEFADACLIARRLAERGVRISQVYYGNGQPWDDHADIMNHRDHAAKSDQPIAALLTDLKSRGLLDDTLVVWGGEFGRTPTSEGSKGRDHHSLGFTMWLAGGGVKGGHVHGATDELGFVAIEDKVHVHDLHATILHLLGMDHERLTYRYSGRDFRLTDVHGEVVHGIIA
>NC_019892.1|WP_015246289.1|3566573_3569381_-|DUF1553-domain-containing-protein
MSRNSLFLSWVVIGGFLLLPSAIALSAEEAKLDPAQVEDFEKNVRPVLATKCVGCHGPDKQKGGLRLDSRTSMMQGGDSGPAIAPGDPEQSRLVEAIRYGDDLQMPPKGKLKEAEINALTRWVKAGALWPEIRLESAAAPPAPSVAATAGISEQDRAFWAFRPITSPPPPRVQDASWPRSSIDDFVLNKLDSAGLKPVAPADKRTLIRRATFDLIGLPPTVEEVDAFLRDESPEAFARVVDRLLASPHYGERWGRHWLDVARYGEDQAHTFEARQYPSGFRYRDWVVKSLNDDKPYDQFVMEQIAGDLLDGPNRDERLAALGFFALGPVYYGKAVYDELDDRVDTLSRGFLGLTVACARCHDHKFDPIPQRDYYALAGIFASTQYKEYPQAPADVIARYDQAQAAIKAKTDEIATFQRSASTRLSEELVSQTARYMVASWKLVNRRKVEPTLRTASVAKAEQVEAFFLDRWVKYLWPEQAVERPYFARWHKVVDAQDKAVDLSADSVAVAQVTEAARQFETYLQSLVAVRKAVEAQQNAAKAIGLEPKSTEADSSLTGIDGQVFGEIASRDGLFAIPKDRVDGLMTADLKAALKALKSDLNRLKKEAPPKYAVTHALAEGTSIADMKLFLRGNPETPADEVPRRFLSVLSQETPAPFRQGSGRLELARAIASPANPLTARVMVNRIWEHHFGRGLVGTPSNFGHMGERPTHPELLDHLASRFIALGWSMKALHREIMGSATYQLSGQFNERNNEVDPDNHLLWKMNRRRLEVEAWRDSMLAVSGTLDPTIGGPSIALTSSDNKRRTFYASISRHNLDGLLRLFDFPDPNITSDKRTVTAVPLQQLFVLNSDFMERQAKALAARLQAASNSSLAERIMQAFLVLYARPASEREVQWALEFLGEGEPTPQGQGGGALSKWEEYAQVLLGTNEFTFVD
>NC_019892.1|WP_044147578.1|3569671_3571060_-|DUF1501-domain-containing-protein
MISRREILARASGGFGAIALAGLLAEQQAAASTADPLAPQPPHFVPKAKRVIFLYMTGGVSHVDSFDPKPLLMAGHGKSITVDNWQGKKGAFQRFFKRPNWEFRPGGRCGTEISDLFPHVRDRADDLCVVRSMSSDHTNHYEGTLGMHTGSFTFARPSIGAWVSYGLGTENRNLPSFMVIAPAAPYAGTQTWAADFLPGCHQGTQVVPGPTPIPNVRPLISVEARQKRELDLIARADRRHLAERPADAALEARIRSFETAFGMQNEAPQAFDLSGESDTTLALYGLERGQTTGFGWQCLVARRLAERGVRFVELIDTGSSGNWDSHGDMQDHASLAKKVDRPIAGLLTDLKQRGLLEDTLVVWTTEFGRTPYHEQAGHAGREHHHQAFSSWLAGGGVKGGIVHGATDDYGVAVARDRVHVHDFHATILHLLGLDHERLTFRHVGRDYRLTDVSGEVVKDVIA
>NC_019892.1|WP_015246291.1|3571094_3574148_-|DUF1549-domain-containing-protein
MRLGLAWLVVMTVGPGSAVAAPPDGPGEAFFEQKVRPILVASCAKCHGAKKQESGLRLDARSALIQGGDSGPAIVPGDPAKSLLMQAVNHQGDFAMPPTRKLSDEQIGVLKLWIERGAPWPGGDRPVAVRSGAITDEDRRFWSFQPVVDPPVPAVADRAWPRTEIDAFILARLETASLKPSPQVDRRTLIRRASFDLIGLPPTPAEVAAFVADPAPDAFARVVDRLLASPRYGERWGRHWLDVVRYADTAGETADFPIREARLYRDYVIDAFNHDKPYDQFIREQVAGDLIAATTPANHAELVTATGFIATSRRFGFDPQNYQHLTIQDTIDTVGQAVLGLSLGCARCHDHKFDPISAADYYALYGIFDSTRYAFPGSEEKNRPRDLVPMVPPAEAAARQKTYDETLARLIAEVKEVDARKAAIEPEFRAVVGIDGSFEAQKIAMGPGIPWGYFDGARVTASSQSPYTNVYPTGSRGISLPNNAANNAIVQTLPVNRKPETHDRVYYNLDFRFASGGNGTYRIYLGHGPGQSAAVELYFNAHQFFVRSGDAHEPVRELREGVWYNLQVVADLDARTYSGTVGLPGELTRFSGKAFSSGWDGNLDCTFIDGYGQIPGHKPASDVDNLAVSDAPFPPPDEPSAGSASDRSIEAYTKVGTLRAALGDLDARRAVAEQARTALQTAGPFPLAYGVTEGNAHDARVQKRGEPTTPGDEVPRRFLQILGGDRVPPDSGSGRLALAEWLTRPTNPLTSRVMVNRVWQHHFGRGLVATENDFGRRGLAPTHPELLDHLARRFINGGWSVKSLHRLIMLSSVYQTAGAGDSAPDLLGRFPRRRLDAEEIRDAMLFTAGTLDTTPAGPHPFPPVETWGFTQHSPFAAVYESNRRSVYLMTQRLKRHPYLALFDGPDPNSSSPHRSATTVPTQALFFMNDPFVHGQAAALGRRLASADLDDRARLRLAFETTLSRPPSADDEADALAFLAAEREDLGASNVAPPEADALAWSALARTLYSRNEFLFVD
>NC_019892.1|WP_015246292.1|3574718_3576719_+|retroviral-like-aspartic-protease-family-protein
MMSSRSRSLVVFASLAVVMTLFGFLVGRMSVSQHPQQPIQATAPKTAPAVVKASPPAAEAVVPPESTEDEAAALASVKEPPPVERTKPEVVRAARAEEPIPVVVPPAGPSVSSASEGEKPDPDEVLKAKGLSRSGRVYVLASDDAIRTKEVEEFRQVQAEWERIAARMAQLVNTAAKQQKLLQAWEYECRQGYQAMAGLQAKQLERNQLRNQASTETTQKGTQNSIGDKTADLTDAAERNQWQILQRRNMSLEYQASELQFQLIQAQREYDQLGSMALAKEAEIQKRQAALILTEESVQKRYDDLANDRQVIAALADLNRDADLKFALGPVENYRANVSKMLSGLLQSKDLHASSKGKKLVVGLDQNVNSLAFQTTTFEDRLGSALSKQKDQQREDESRPKKREELAASVQRLEDQVANATQATRKAQLSAQLAGARAELANLQRDEVEGEEVRKKLAENVATNRDGYVQNVIALRKAVDLSQEKHDQLETDPTVKKAKSRLKATVVPLPKGALDILKKAEKLIQTVEIPVEADKTAFQVDAILNGQSQKLVVDPTIDVIRLSKAIAAELEIELSEDAPEFDLVMEDGRTLRAKRTTIKSLAVGPFLTPDVECLVVLNDYDAPPVLGANFLNQFSYKFDPTAGKLTLTQVNILPKTKPSERSRSSK
>NC_019892.1|WP_015246293.1|3576755_3579374_-|protein-kinase
MPPASVCPKCHNPLPENAPLGLCVPCTLRIFQEDQSETTVKLRGWKEHLRTTDAEARGQSAEAFAWFDLCETASFQASKGVSGGHDSRERGFGRFVSVETLLNSLIQLELMEPVELQEFLKQFPADLDPKNPEELARGLVRSKRLTEYQAGALLQGKSKGLVIDKYLILDKLGAGGMGMVFKALHRRIKRVVALKVLPPSFAKDETAVRRFRREAEAAAKVSHPNVVAVLDADEFNGLHFFAMEYSAGKDLKRLVETRGPLPAAQAIECVLQAARGLGAAHARGIYHRDIKPSNLLLDPRGTLKVLDLGLARMMDKGAELLGSVEPDPELTRPGSIMGTVAFMAPEQAYNSRSADHRSDIYSLGCTLFYLLTGRPPYDGDTLMARLIAHREEPIPSLIGSQPDLPPVLDVTLRRMMAKSPQDRYQSVDELISALQSCQSFGSTIEEGASWRGLDSPLNVDRSQSKPVNASPLSGLVSGAETSGRFRPWFFRRVAALVLAIGLASLAMVVPARMRAKVREPMASGDLSNSEVRSKRSDKLVLPEPLRSLPESIVPRSDPAPPSIVAKEETKVEPEPVEPVGEIRRFAGHEDRLVESVAVSADGRHALSAGLDCTVRYWKVSTGEEVRRFVHDGPVFSVAFSHDDRLALTGGADKVMRLWDLEAGRELPPFKGFTEPIYSVALSPDGQYALSGSRDKSVRLWDVATRSEIYSLLHEGAVTAVAFSPDGERVLTGSEDKTVRIWKVLAPNEAHDFKSQAKVLCAVFSPDGHRALSGGDDGSVVLWNLDSKRMIRRIEGPHDQVRCVSYLPDSRHALWGTKAGRLILGNVEDDREVDRFGATAGRLGVAVLPDGRHALTSDDDGFVRLWKLPPILE
>NC_019892.1|WP_015246294.1|3579839_3581333_+|sodium/solute-symporter
MHPIDLGVIIVYIVGCTAMGAWLGSGSKGLKGYFLGESNIPGWAVMISIIATETSAVTFLSVPGIAYRGNMTFLQLAIGYILARIFVAIFLLPAYFKGEIFTAYQVLQQRFGAATQKAASVLFLVTRTVASGLRLFLAAKVLRQMYLATQGYPVSSGWEMPIAIITIGLFTIVYTYLGGIKAVVWTDVLQFFIYILGGIVALAILIGEVPGGWSTIVKEGLAANKFQVFDFRFDLTIAYGFWAGLIGAMVLDTGSHGVDQMMVQRYLSARSQREAAWALIASGGVILVQFTLFLLIGVGLFVLYQHSPPPVLPTKDEEFASFIIRYLPTGVLGVVIAAILSVTMSTVSGALSASASSTVNDLYRPLFPNTDERNLLRLSKGLTAFWGIVQIGVAIAAIALEKAVIDNALAVAGFVTGILLGLFLLGLVSRHSGQAAAFIGMIAGLVAVSFAAFGTKLAYPWYALVGSATVVAVGMAVSLVLPAAPRKIIDTNLQHES
>NC_019892.1|WP_020466179.1|3581333_3583685_+|DUF1343-domain-containing-protein
MMNAARFVLLLSLLASPVAARAALPEAEPGTVGLDAERLARIDQAVERAIKRKEVPGAVVLVGRRGKVAYVKAYGQRTVEPTATAMTRDTIFDMASLTKPVATATSVMRLVEQGKIKLGDSIVTYLPEFDNHDKKAITVEHLLRHRTGLIADNPIADYADGSEKAWERIAALKPNSPPNERFLYSDVNYLVLGRLVERVSGKPLDQFARETIFEPLGMTDSRFAPLVEGTKPNPAIDLERCAPTEKEAGNWVHGVVHDPRARALGGVAGHAGLFSTADDVAIYAQMLLDGGKGPDGKAILAPETVQAMLDPGNTPPRQRRGLGWDIETPFSHPRGRGFGQGSFGHTGFTGTSIWIDPATQTFVIILTSRLQLGSKANTAPIRSEVATLASAAILDRPKDAKPSETHLHPVDCGIDVLVKSKFERLRGKRVGLVTNHTGKTKDGVPTIDVLANAPEVKLVALFSPEHGIRGLVDAEVGDSKDEKTGLPILSLYGKSRKPSKENLAGIDILVYDIQDVGVRFYTYISTLGLVLEAAKENGIPIVVLDRPNPIGGVEVSGPVRDDGFEAFIAHHAIPVRHGMTVGELARLFNTERKIGADLQVIACEGWQRKDLFDWTGLTWTNPSPNMRSLNEALIYPGVGLLEATNLATGRGTDTPFERLGAPWIDAREFSAALNGRGLPGVRFVPNNFTPKERQYAGKECGGVQIFITSRDQFDPLALGIELAVVLRELYPERWEHDGFLKFIADRATYDALLKGENGQAIRTLWDAELAQFRTIREQYLLYK
>NC_019892.1|WP_015246296.1|3583725_3584643_+|N-acetylmuramic-acid-6-phosphate-etherase
MLLEDRLLTEARNPESEAVDRLNSRELVALMTSEDTKAVEAVRAESDAIATAIEWAAERFGRGGRLIYVGAGTSGRLGVLDASECPPTFSVPPSMVVGLIAGGPTALTRAVEGAEDDPVQGAADLRALAITAADLVVGIASSGRTPYVLGAIEQAKAVGASTVGIACNRPSLLGAKVDLEIALLVGPEVITGSTRLKSGTATKLVLNMITTGAMVRIGKTFGNQMIDLQPSNEKLRIRTRRILREIAGLDDAQAADLLRRSSGQLKRALVAALAGVEPDQAQALLDAHGGQVRAAVMATTGVDPR

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Crispr_ID: NC_019892_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_7

3821586-3821745

Orphan

Consensus_repeat	Method
TTTTCGCAGCCCCGAAGGGGCGACCGT	PILER-CR

2 spacers

The CRISPR arrays of NC_019892_7

>merge|NC_019892|7|3821586-3821745|PILER-CR
TTCGCAGCCCCGAAGGGGCATAAGCACCTGGAAACAGGATAAGCTCAAAATCAGATTTTTCGCAGCCCCGAAGGGGCGACCGTTCCTAGCCAGGGGCGCAAGCCCCTGGAAACAAGACAAGTTCAAATCAAGATTTTTGCAGCCCCGAAGGGGCGACCGT

>NC_019892|7|3|3821586-3821745|PILER-CR
TTCGCAGCCCCGAAGGGGCATAAGCAC	CTGGAAACAGGATAAGCTCAAAATCAGATTTTTCGCA
GCCCCGAAGGGGCGACCGTTCCTAGCC	AGGGGCGCAAGCCCCTGGAAACAAGACAAGTTCAAATCAAGATTTTTGCA
GCCCCGAAGGGGCGACCGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_052315635.1\|3813762_3814851_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223566
NC_019892.1\|WP_015246485.1\|3830473_3831901_+\|magnesium-chelatase	unknown	unknown	gnl\|CDD\|224160
NC_019892.1\|WP_015246472.1\|3808655_3809906_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NC_019892.1\|WP_015246488.1\|3834824_3835595_+\|3',5'-cyclic-nucleotide-phosphodiesterase	unknown	unknown	gnl\|CDD\|293821
NC_019892.1\|WP_154673688.1\|3835701_3837072_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223963
NC_019892.1\|WP_015246473.1\|3810001_3810883_+\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
NC_019892.1\|WP_015246486.1\|3831947_3833090_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|227204
NC_019892.1\|WP_015246478.1\|3815819_3816935_+\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NC_019892.1\|WP_026011983.1\|3837257_3838946_+\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|224720
NC_019892.1\|WP_015246479.1\|3817186_3818248_-\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|133475
NC_019892.1\|WP_015244304.1\|3824997_3826371_-\|transposase	unknown	unknown	gnl\|CDD\|371130
NC_019892.1\|WP_015246484.1\|3829293_3830283_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
NC_019892.1\|WP_015246480.1\|3818715_3821544_+\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|178177
NC_019892.1\|WP_015246474.1\|3811028_3811640_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239516
NC_019892.1\|WP_026011985.1\|3811739_3811928_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015246481.1\|3821862_3824724_+\|hsp70-family-protein	unknown	unknown	gnl\|CDD\|378872
NC_019892.1\|WP_015246487.1\|3833223_3834624_-\|Si-specific-NAD(P)(+)-transhydrogenase	unknown	unknown	gnl\|CDD\|235373
NC_019892.1\|WP_020466121.1\|3814996_3815734_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|181382
NC_019892.1\|WP_015246475.1\|3812189_3813131_+\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|187542
NC_019892.1\|WP_015246483.1\|3826857_3828948_-\|redoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|215497

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_052315635.1\|3813762_3814851_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|223566	COG0492, TrxB, Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones].	9.72667e-50
NC_019892.1\|WP_015246472.1\|3808655_3809906_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NC_019892.1\|WP_015246488.1\|3834824_3835595_+\|3',5'-cyclic-nucleotide-phosphodiesterase	gnl\|CDD\|293821	cd07735, class_II_PDE_MBL-fold, class II cyclic nucleotide phosphodiesterases Saccharomyces cerevisiae PDE1, Dictyostelium discoideum PDE1 and PDE7, and related proteins; MBL-fold metallo-hydrolase domain. Cyclic nucleotide phosphodiesterases (PDEs) decompose the second messengers cyclic adenosine and guanosine 3',5'-monophosphate (cAMP and cGMP, respectively). Saccharomyces cerevisiae PDE1 and Dictyostelium discoideum PDE1 and PDE7, have dual cAMP/cGMP specificity. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	2.20525e-50
NC_019892.1\|WP_154673688.1\|3835701_3837072_-\|hypothetical-protein	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	0.00527421
NC_019892.1\|WP_015246473.1\|3810001_3810883_+\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	1.54162e-179
NC_019892.1\|WP_015246486.1\|3831947_3833090_+\|VWA-domain-containing-protein	gnl\|CDD\|227204	COG4867, COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain [General function prediction only].	4.02435e-51
NC_019892.1\|WP_015246478.1\|3815819_3816935_+\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.84372e-10
NC_019892.1\|WP_026011983.1\|3837257_3838946_+\|glycosyltransferase-family-39-protein	gnl\|CDD\|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	1.2106e-56
NC_019892.1\|WP_015246479.1\|3817186_3818248_-\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|133475	cd06583, PGRP, Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20 kDa) extracellular proteins; intermediate PGRPs (PGRP-I) that are 40-45 kDa and are predicted to be transmembrane proteins; and long PGRPs (PGRP-L), up to 90 kDa, which may be either intracellular or transmembrane. Several structures of PGRPs are known in insects and mammals, some bound with substrates like Muramyl Tripeptide (MTP) or Tracheal Cytotoxin (TCT). The substrate binding site is conserved in PGRP-LCx, PGRP-LE, and PGRP-Ialpha proteins. This family includes Zn-dependent N-Acetylmuramoyl-L-alanine Amidase, EC:3.5.1.28. This enzyme cleaves the amide bond between N-acetylmuramoyl and L-amino acids, preferentially D-lactyl-L-Ala, in bacterial cell walls. The structure for the bacteriophage T7 lysozyme shows that two of the conserved histidines and a cysteine are zinc binding residues. Site-directed mutagenesis of T7 lysozyme indicates that two conserved residues, a Tyr and a Lys, are important for amidase activity.	2.71188e-22
NC_019892.1\|WP_015244304.1\|3824997_3826371_-\|transposase	gnl\|CDD\|371130	pfam10551, MULE, MULE transposase domain. This domain was identified by Babu and colleagues.	6.4125e-08
NC_019892.1\|WP_015246484.1\|3829293_3830283_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	4.08502e-140
NC_019892.1\|WP_015246480.1\|3818715_3821544_+\|leucine--tRNA-ligase	gnl\|CDD\|178177	PLN02563, PLN02563, aminoacyl-tRNA ligase.	0
NC_019892.1\|WP_015246474.1\|3811028_3811640_+\|NUDIX-hydrolase	gnl\|CDD\|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	6.85358e-44
NC_019892.1\|WP_015246485.1\|3830473_3831901_+\|magnesium-chelatase	gnl\|CDD\|224160	COG1239, ChlI, Mg-chelatase subunit ChlI [Coenzyme metabolism].	3.91762e-60
NC_019892.1\|WP_015246481.1\|3821862_3824724_+\|hsp70-family-protein	gnl\|CDD\|378872	pfam12531, DUF3731, DNA-K related protein. This domain family is found in bacteria, and is approximately 250 amino acids in length. There are two conserved sequence motifs: RPG and WRR. The proteins in this family are frequently annotated as DNA-K related proteins however there is little accompanying literature to confirm this.	5.95603e-107
NC_019892.1\|WP_015246487.1\|3833223_3834624_-\|Si-specific-NAD(P)(+)-transhydrogenase	gnl\|CDD\|235373	PRK05249, PRK05249, Si-specific NAD(P)(+) transhydrogenase.	0
NC_019892.1\|WP_020466121.1\|3814996_3815734_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|181382	PRK08317, PRK08317, hypothetical protein; Provisional.	2.27592e-13
NC_019892.1\|WP_015246475.1\|3812189_3813131_+\|NAD(P)H-binding-protein	gnl\|CDD\|187542	cd05231, NmrA_TMR_like_1_SDR_a, NmrA (a transcriptional regulator) and triphenylmethane reductase (TMR) like proteins, subgroup 1, atypical (a) SDRs. Atypical SDRs related to NMRa, TMR, and HSCARG (an NADPH sensor). This subgroup resembles the SDRs and has a partially conserved characteristic [ST]GXXGXXG NAD-binding motif, but lacks the conserved active site residues. NmrA is a negative transcriptional regulator of various fungi, involved in the post-translational modulation of the GATA-type transcription factor AreA. NmrA lacks the canonical GXXGXXG NAD-binding motif and has altered residues at the catalytic triad, including a Met instead of the critical Tyr residue. NmrA may bind nucleotides but appears to lack any dehydrogenase activity. HSCARG has been identified as a putative NADP-sensing molecule, and redistributes and restructures in response to NADPH/NADP ratios. Like NmrA, it lacks most of the active site residues of the SDR family, but has an NAD(P)-binding motif similar to the extended SDR family, GXXGXXG. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Atypical SDRs are distinct from classical SDRs. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.35582e-71
NC_019892.1\|WP_015246483.1\|3826857_3828948_-\|redoxin-domain-containing-protein	gnl\|CDD\|215497	PLN02919, PLN02919, haloacid dehalogenase-like hydrolase family protein.	1.18007e-151

>NC_019892.1|WP_015246480.1|3818715_3821544_+|leucine--tRNA-ligase
MPAYHVQRIEKKWQAYWERNKTFRTPDVAPGKPKLYVLDMFPYPSGAGLHVGHPEGYTATDIVCRYKRMRGFNVLHPMGWDAFGLPAEQYAIKTGTHPRITTQNNIDNFRRQIKSLGFSYDWDREIDTTDPHYYKWTQWIFLQLFDTWYDPDFAWTDPDGRPRKGKGRPIAELPIPAGTANPDAYRDSKRLAYRAEVPVNWCPELGTVLANEEVIDGKSERGNHPVVRMPLKQWMLRITAYADRLAEEIEFVDWPRAIKEMQRNWIGRSEGAEVDFFVGQDVSQWREGRRASGWPESPGNDAIRVFTTRPDTLFGATYMVLAPEHPLVDRLTTPDRREAVESYRRATSGKSDLDRTDLAKTKSGVFIGASAVNPVTGRSIPIWIADYVLMGYGTGAIMAVPGHDIRDFEFAQKFALPILRVVARSADLAGAALETAEAEYGVAVNSHGGVDGVSIDGLPTDQAKASITTWLEQHGLGHKTVNYKLRDWLFSRQRYWGEPFPILLGEGETLKAVPEAELPVLLPELADFRPSGKPEPPLGKATDWIQYSSTYQRETNTMPQWAGSCWYFLRYLDPTNDKRPWNPELEKYWMPVDLYVGGAEHAVLHLLYSRFWHKLLFDRGHVSTPEPFQRLVNQGMILGETEYTGYQNEADRWVSVAKVKETENGHADLEGQPVKPVKLEPEQVVKKGEGFVLADDPEIRIDARAHKMSKARGNVINPDVVVDEYGADSLRLYEMFMGPLEAVKPWNMKGVEGVFRFLSRAWRMIVDADAEALGLDPKVQDVPLTPDQAKLVARTVAAVSDDLDAMRFNTAISRLMEFTNAFTGQDVRPKSAMETFTLLLAPMAPHIAEELWELLGHTDTLAYHPWPTFDPALLKDDEVEVPVQVNGKVRGRVVVPADAGRDAIEAAARADEKVAALLEGKAIKKVIVVPGKLVNFVVAGPS
>NC_019892.1|WP_015246479.1|3817186_3818248_-|N-acetylmuramoyl-L-alanine-amidase
MVLHPPASFVLRPRRGMILLAAAMLMSTSMGCSQRRTTMRPVFMSPRYRVSRPVLIPNNCPTGNCGGSSIGSSQTTIETAPTILPAPGSSAIESVTPSLNAPVSPRIDEPVTPAGISPPRPNAVPDEPTLELNGATETPPTASPGPNSSLTPQNRGASRPLPSTSQGASRRSLYGRPREASLRERLRPFVNDPEDLFTPPKADRPWKYVVMHHSAHSSGGLNEIDREHRKVLGWEGCGYHFVIGNGTGSPDGQVEVAQRWSNQKHGVHCRDGKTSEVNEYGIGICLVGDLDSAGPTPRQIEAAKALVDYLGDRYQIADDRIGTHSTLAASPTACPGKHFPAQAIMGSRNYAQR
>NC_019892.1|WP_015246478.1|3815819_3816935_+|IS630-family-transposase
MRGRKPRSLRIVPHDAPILQEIARSRSLPWYQVQRARIVLGVAAGEPIQLLAVQTQHDPSTIWRVCRRYEGSGLSGLLAPPQRTGGSPGFPPLQRAQIVRLACLEPIAKGLHITHWTSKDLARQAVEDGIIPSISDRTVRVILNEVDLQPHRTRYWRTARVDPEFKRRAEKVLWCYANADRLARRGYWVVCADEKPNCQVLERPPIRRSIPGSIEQQEFEYTRHGTVNILAFLIVHSGRMEASCIETKNAKTYVDELAGFRRRHRHLRGVYLIHDGDPSHTAAATEVYLDDCHGWWKRRFTPVHASWLDQAEILLNAFSYHYLKRTSWRSREEFIEHVEHAWPEYNRLYAHPFEWTWTNHKMRQWYANHVT
>NC_019892.1|WP_020466121.1|3814996_3815734_+|methyltransferase-domain-containing-protein
MNNSIVLSVFLILGGMMGCTKPTESAAPVVESNKVAEQGLEQEEANMHGEHEHHHSGFDDPKKFETRWNDPERDNWQHPEEIIAALALMPGATVADIGAGTGYMVAHLSKTVGDIGTVIAIDAEQAMITYLARRSGDLGPARIVPRKVRAESPDLENDRVDGAVALNIWHHIGGREAYAKKVYAGLRRGGRFVVVDSKVDAISGPPQKMRLEEGQVVKELEAGGFRAEVAHESMPQHYMIVGHKD
>NC_019892.1|WP_052315635.1|3813762_3814851_+|FAD-dependent-oxidoreductase
MTGGKIGADGGAITRRQALATAASAGVLLGGVPSNAREEGPMTASNRLYDRYDVVVVGGGPAGLSAALVLGRACLEVLVCDSGKGRNAPAAGVHGFLTQDGTPPAELRRIGREQLRPYEVHFHEGAVVDARKTEGGFEVTLDKAGVIACRKLILATGMADVLPEIPGLRELWGTSVIHCPYCHGWEHRGQPWAALVPPETAIETATTLLGWSNQLTLLTNGPSRLAPDDRAWLEEHAVEVVEGRVERLEGNGGQLQAIWLEGSRRLEREVLFVRTQLRQPSDLPKRLGCELIADGPKAGMVRTDPFGATGVEGLYIVGDASHAGVPSVASAVAEGSIAATLASKAIFTEETQRPAGGPVRRE
>NC_019892.1|WP_015246475.1|3812189_3813131_+|NAD(P)H-binding-protein
MSIDAPILVTGAAGRLGGVGGEIVEILRSRDLPVRALVRTDDDRAEALRATGAEVVIGDLTRATDVARALEGCRRMYFGMSVSASYLEATVTAAAAARAHSDLEVFVNISQLTVSQMSLLAMTDSLQQRMHWLGEQALNWSGLPVVHVRATVFLQHFFFSQWAAESIAKDGTIRLPFGDARTSPIDTRDVAEVIAAVLEHPEPHVGKVIELTGPKSEDMRAVAAEYSEALGRTITYVDVPMAEWQERELPAHGLPEHVASHMKTMAQLHADNRYDRLTHDFEAIIGRPATSIREYVAKHPEMFGSSKPSPVFP
>NC_019892.1|WP_026011985.1|3811739_3811928_+|hypothetical-protein
MSTGTSISLNLSIWGTFFSLCSLLDGNSRFLIHGEIRKGITERGVETIVQRVPVNTTAAPGP
>NC_019892.1|WP_015246474.1|3811028_3811640_+|NUDIX-hydrolase
MSDPEHHNPWTTLDSRLVYENPWIAVREDQVLQPNGAPGIYGVVQFRNQAVGVLPVDEQGRIWLVGQYRYPLQRYSWEIPEGGGHFDESPEDAARRELREETGLTAGRLELISKSHLSNSVSDELGFIYRATDLEEGISEPEGSERLQVRRVEWPEAWAMLQDGTITDSMSVIALLHEAVRRGGINTKTNDHARQTARRDKPT
>NC_019892.1|WP_015246473.1|3810001_3810883_+|succinate--CoA-ligase-subunit-alpha
MSILVDKNTRLICQGITGKAGKFHSEQCRDYGTTLVGGVTPGRGGESVLGVPVFDTTSEAVKATGANASMIFVPPPGAADAILEAADAGIPLIIAITEGIPVLDMARAVAYLKAHHPNTRLIGPNCPGVITPGQCKIGIMPGYIHKPGKVGVVSRSGTLTYEGVWQLTNLGIGQSTCVGIGGDPINGTDFVAALRLFEADPNTEAVLMMGEIGGNAEEQAAALKKSGEFTKPLAAFIAGQTAPPGKRMGHAGAIISGGSGKASDKIDALEDAGIRVAKSPADMGAALKAALKG
>NC_019892.1|WP_015246472.1|3808655_3809906_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MKVHEYQAKDLLRAAGVAVPDGIVITSAEEAGAAFDQLKGGLIVVKAQVHAGGRGKGVAIGPDDDRAKALEIASGQAPRPDGMAKGVQLVRTREEAVKAAASLLGKTLVTYQTGAEGQAISKVLITVGHDIVRELYLGLAFDRALQCPVLMASTEGGVEIETIAHTHPEKIHREPIDVGLGLAGFQARKVCQVLGLKGETAKKGEVFLKNFVKLFLDTDASLAEINPLIVTDKGDVMALDCKFNFDDNAMFRHPAIAALLDVAEEDPAELRAGKSGLSYVSLDGNIACLVNGAGLAMSTMDLIKYHGGEPANFLDVGGGASKEQVLEGFRILLASPRVKAVLVNIFGGIMKCDIIASALLAAYGELDFRVPLVVRLEGTNVEAGRKMIEESGRNIITAMGLTDAAEKVVAAAKGAA
>NC_019892.1|WP_015246481.1|3821862_3824724_+|hsp70-family-protein
MARSRYIVGIDLGTTNCAVAYVDTKGRERPTADIRLFSVPQLVAPGETAPRPMLPSFLYLPGTHDLPAGAARLPWKDDADRIVGEFARIQGAKVPAHLVASAKSWLCHSGVDREAEILPWASPPGARKVSPVEASADFLRHIRDAWNDQFARDDQTLRLEQQEVVLTVPASFDEAARELTVDAAKKAGLTTIILLEEPQAAFYCWIVSHQEGWQREVRGGELILVCDIGGGTTDFSLITVVETPTGPGFRRVAVGDHLMLGGDNIDLALAHRVEKKLGGVKLDAEQWSALRHACRTAKEKLLGDLPAERWPVTIAGRGSKIIGGSIQSELTRDETLEIVRDGFFPRITRSEEPDRTTKLGLQEFGLPFVSDPAIPKHLNAFLRRHRAEAVGQGGHAPDDRPARPDAILFNGGALTPTVVRDRLVEVVSSWFPDDPGAPYAPRVLSNASLDLAVAYGAAYYGVVRRGGGIRIGGGTARSFYVGFQSETVDRPWLCVVPRDAQEGDEIAIDNRDFDLLMGQPVAFPLASSSVRPDDKPGDLVPSDPDSIRELPPLQSLMRVGRKAKAERAPVRLAARVTEVGTIELWCQSRTDDRRWRLQIQLRGPAGTPAPSGSVTGRENDRVVIEQSILDTAIEAIQVAFGPVTPSEELGPSRLIKRLEEILDSPRDQWPPSALRAMWEPLRDLAEARLKGPRHESRWYNLAGFCLRPGTGFPLDETRIKAVWPVFHQGVRHTKDLQCWAEWWILWRRVSAGLSRAHHDEISRRLIPFLVPSKAAATKKGGRPRPEAHELAEMWRCAASLERLAPDLKVSYGNALVKELSLRESLAHHLLWCLGRLGARVLLYGPANTVVPRETAERWTRSLLERPFAPGRETTDAIFALAQLARVSGDRARDLDDALRTEVLQRLEALGADEVIRRPVREYHELEAEQQGQALGDALPVGLRLLAGAETAGS
>NC_019892.1|WP_015244304.1|3824997_3826371_-|transposase
METQRPPTLTIPISCCPKKAPCPTCGKLGRRKDVLNRLIRSIAYHQVVYLDVTYGEYRARCHCCSTFRTMPTSVEFKARYDNKVRQAVLDRILEDGMSVERVIQSIHRDFLLDLSDGFVYDCLLHQAKRLDMAEHRRWVLEHFRGTLCVDELHLGRYALLLATDPLNDLAVAFALVASNDKDHMRRFLKNLKTWGLEPEVVVTDGSDLYPAVLAELWPSARHQLCVFHVLKDLHKLVLDALRRFRRGLERRGNRGRKRRRGRPSGGRKPRHRSTYKEKSAFIFSHRFLIVRRRDQMSRQERIDLNTMLNDLPELRPLRQFVDALQRLFAENQGEATAWRRHQRLTTDRDFLGVPELVKAVKKLGPEKFAKMIAFLGSAACRRMRTNNHVERINRKLRHEEKARYKWRSRRTIVRFMVLLLDRYWEHEKAARSRWLDETPPIELARESPKTVPRPRVA
>NC_019892.1|WP_015246483.1|3826857_3828948_-|redoxin-domain-containing-protein
MRQPKSIARWFLSLVLTSSLVLSIAAGLVSTQAKAGSDPTGKAAPRTIRIERTAFMEAPPKLSLEGGVDWINSGPIRLEELRGKLVLLDFWTYCCINCHHVLPDLAKLEQKYKDELVVIGVHSPKFDEERQTENIRRKVAEYQIKHPVINDADQVLWNRFGADSWPTMVLIDADGTPIGKVSGEGNYAILDHEIGLRVAKHKAKGDLNTTPFQFSAESDKPDTSPLLYPGKVLADEKSKQLFIADTAHNRIVLTDLDGRKSVVVGSGGIGMVDGDYAKAEFNRPQGLCLVDDTLYVADTENHAIRAIHLKTKQVSTVAGTGQQGHRRSGAGAGKATSLSSPWDLVLIPGTKTLAIAMAGTHQIWRYDIPSDSVTIWAGTGQENIEDGPVSTALFSQPSGLATDGHNLFVADSEVSAIREIVLDKKKPVVHTIVGQGLFVFADVDGKGDVVRLQHCLGVAYGGGKLFIADTYNNKIKVCNPATRTVETLVGNKQPGLTDDPPRFYQPGGLSVAGTNLYVADTNNGLIRVVDLGEKTVRTLEIAGLTPPAPPKRNPTFPRAKEVTLETAQVAPGKDLTFDVTLPSLDPGYKISPDVPMSYLVETPEKIGILATTSTGGRKLDPPAEVFTIKVDLANATKEGDSFTIRLSVKSFVCSKDSSLCTDKNYVWTIPITVVAGASDRVRIGSTDSEKSERATD
>NC_019892.1|WP_015246484.1|3829293_3830283_+|ribose-phosphate-pyrophosphokinase
MDKSLVCNASSKDNDPFGELKIFSGKASKSLASEIGAKLGIELAQSETKTFSEGNVFVRVLENVRGRDVFIIQGTEYPVNDNFMELLFWIDAFRRASATQVTAVIPFFSYAKGDKKDEPRVSIRARVCADAIEAAGADRVLTMDLHSPQIQGFFKIPVDHLYAMPVLVDYFRKKQIPDLVVAAPDVGFGKQAYRYAQMMHTNVVFGNKVRHSHDEKAEMLDIVGQVEGKNVLIVDDFTISGGTLIEMAKACKERGALDVYACVSHGVFSKGSAEKIARSPIKELVLTDTIGHRFEPLAPCCKVISVAGLFAEAIQSIHRRESVSRLFDF
>NC_019892.1|WP_015246485.1|3830473_3831901_+|magnesium-chelatase
MATERPRTLGDLRASGYRMESVKDEMRRNLIATIQAGRPLFPDILGYEETVVPQIQNAILSRHDILFLGLRGQAKTRMLRQLVHLLDDAMPIIAGSEVNDHPYAPLSKEARDRVAAGGDATPIAWVGRDARYQEKLATPDVTIADLIGEIDMIKHAEGRYLSNELTMHFGLIPRTNRGIFCINELPDLSPKIQVGLFNVLEERDVQIRGYPIRLTLDLCMVFSANPEDYTNRGRIVTPLKDRIGSVVRTHYPLTRELGIAISDQNAWLDRTGGELAIPIYVKEIIEEISRLARSSSHVNQQSGVSVRMSIANLENVVSNSERRALLCGERWIVPRVSDLAHVATSSRGKLELTMSEDDGNEDKLISRIVDEAVKNVFAQHLDAREFRAAVGYFESGNGIEMGDTLPAQEVLSRIEKVPHLRKRADEFARQVQPELTDSDARDISVAAAAEFILEGLHVHNKLNKSSKAGSTSYKR
>NC_019892.1|WP_015246486.1|3831947_3833090_+|VWA-domain-containing-protein
MSFYEYSKWDGSQAFQPQSAEKAFDQLSEYLLQHGEQVLRNLDEFEEDEIPDLLQQIEKQGLIEQDGEGKWQVSPKGLRRIQESALTNLFQTFQRDAVGKHDTPQKGEGTVRLDDSRPYVYGDSLANLDLHETLKNGLVRQGGGSPIHLRYEDYVVHDTEFQSRCSTVVLIDMSGSMGRYGKYAMTKKVAMALQAMVRAQYSQDTLQMVGFYTYANRITERELLNSAPKPVSLFDSHVRMRFDLDNPPKRVPEHFTNIHAGLRLARGLLSRQGAQNKQIIVITDGEPTAHLEGREVVLIYPPSEKSASHTLAEVRRCAAAGIRVSSFALIEDYFYLGLVNFVEEMARVSQGVAAYCSADDLGSYVFDSFIGGRRSRRMSR
>NC_019892.1|WP_015246487.1|3833223_3834624_-|Si-specific-NAD(P)(+)-transhydrogenase
MDSSKFDLIVIGSGPAGEKGAAQAAYFGKSVALIEKEPELGGAAANTGTLPSKTLRETALFLSGFRNRDLSGVNLSIKHQVTIRDFLVHEQHVTQEERVRILDNLSRHHVQLFRGTGSFVDAHTISIRSNDGSETRIQGDVVLIAVGSSPFRPPIYPFEDPRVWDSDTILQLQHMPKSMLVVGGGVIGCEYACMFAILGIEVTVVEQRGRAVGSLDAEIAASLQSQMESIGIRFLFNDSVESVHAGEEIDVQLKSGLALKPGAILVSSGRNGNTHDLGLDRVGVVVNERGVVNVNARYQTEAPHVYAAGDVIGSPALASTAMEQARVAMVNAFDLKYKSDMAVILPYGIYTIPECSMAGETEESLKKKGIDYVVGKATYDTNARGHIIGDDKGFLKLLFATEDMRLLGVHIIGEQATELVHVGLTALLLKQGADLFIQTCYNYPTLTELYKYATYDALGRRAAQKK
>NC_019892.1|WP_015246488.1|3834824_3835595_+|3',5'-cyclic-nucleotide-phosphodiesterase
MKVMLVPSSIVTDGEEPSQYLISYLINDSVAIDAGSLGIHGSPSKQAKIKHVLISHTHIDHTATLPIFVENAYEGKSDCVTIHGSETVLENLKGDIFNDRTWPDFVALSEGSAPFLRLELLEPERPLEVEGLKITPISVNHVVPTLGFLIEDSRSAVLIASDTGPTDLLWEYANKADHLDAVFLEAAFPNEMSELASISKHLTPALFGLEVQKLKRKAAVIAVHIKARYRKQILRELSELALPNLQIGQFGMTYDW
>NC_019892.1|WP_154673688.1|3835701_3837072_-|hypothetical-protein
MPSRRPAPTYNPTEDLAEMALQTEAECLLDTGALYGVRVMLRPAQGDPIFAGFKQGAFSLYYGDGPIYHFDREGRWQRAFIHGIHYLKGLDTTIQAIDRVREGVNMVLKRRTLFFAEASDLDASVRATALDLLDALTAGRLERVDPPSKAQPLSTDMLCNFLERIVEWDATAWFAHREKYVATYGVLPFLPPDSQNSLILQATLGHADGIVFGGGSAAPYYQRTSDEFATHTREVVKLFGQRRLQYRNIFLAGSDVLRLPSEAVATFLETIARSELCAPSGGVRDFSEPSPRLEAVHAFLDNMAPPRPSVEQWRTYRQLQLRRVVLGVESGDPTVRGLYRKTWENHDLVALVSDLKQADLAVGLMVLVDAGGAEHAERHLAATVDLINTLELGKGDIVSLLDANEFRDPEQPVPSFAPLVGLRWTEQQAALKHALLPLRSNRGVKVVPYSLEKQGL
>NC_019892.1|WP_026011983.1|3837257_3838946_+|glycosyltransferase-family-39-protein
MPPIFGTEACESRRRLLLEPVLIGLLALTLNLAGNHKTSLWDRDEPRYSACVREMRARGDWIRPTFNGEPRYHKPILIYWLMRGGVALGGDNPFGCRLVSAIAGVGTCLLVRAMGRRMLGPQMGMFAALMLATSPIMVTESKLATTDATLAFWLVGAQFCLWELAQRPSRRLAAGFWTLMALATLTKGPVGAALIAMSGIVSWWWGGPTACWSRLRWRWGLCVFLAVVAPWLVMIGLVSHGEFFRFAIGDQIIQRVATGMEKHTGFPGYYLVTTLGTFHPWSALLPAALFGAWSRRREHPLFGFLLGWAVGPLILLECVQTKLVHYYLPAIPACALLAAWLIALVVKEEVNLRRWPLGRVGVGLLSGTAVVLLGGLIAGATMLPTSLRSPLLFLAVILVSGTTYAVTRIFCGLTERAVGSLVVTWAIFMFAMGTWLLPAAEPYRTSRIVGERFASLAKEHRVQPILNSYQEPSVIYAYGRPLPTVRNWSQVKKLVLQHGAVATAVLPHELSAFLARPEYEVERLDHLTGFNLNKGENESLEFILLRMHRSVRVTGLKQSPVK

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Crispr_ID: NC_019892_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_8

4932027-4932140

Orphan

Consensus_repeat	Method
CTAGCCAGGGGTGAAACCCCTGGGAATAAGATGAGAT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_019892_8

>merge|NC_019892|8|4932027-4932140|CRISPRCasFinder
CTAGCCAGGGGTGAAACCCCTGGGAATAAGATGAGATCACTATCCAATAATTTGTAGCCCCGAAGGGGCGACCGTTTCTAGCCAGGGGTGAAACCCCTGGGAATAAGATGAGAT

>NC_019892|8|7|4932027-4932140|CRISPRCasFinder
CTAGCCAGGGGTGAAACCCCTGGGAATAAGATGAGAT	CACTATCCAATAATTTGTAGCCCCGAAGGGGCGACCGTTT
CTAGCCAGGGGTGAAACCCCTGGGAATAAGATGAGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015247298.1\|4936661_4937126_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247294.1\|4930914_4932006_+\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|275218
NC_019892.1\|WP_015247285.1\|4921000_4921780_+\|glucose-1-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|133015
NC_019892.1\|WP_015247302.1\|4941364_4941694_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NC_019892.1\|WP_015247293.1\|4930202_4930874_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187594
NC_019892.1\|WP_015247289.1\|4925151_4926234_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133030
NC_019892.1\|WP_015247303.1\|4943172_4943523_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247287.1\|4922746_4924078_+\|lipopolysaccharide-biosynthesis-protein-RfbH	unknown	unknown	gnl\|CDD\|237960
NC_019892.1\|WP_015247296.1\|4933561_4934242_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319806
NC_019892.1\|WP_026012166.1\|4943569_4944214_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274375
NC_019892.1\|WP_015247292.1\|4929394_4930210_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226356
NC_019892.1\|WP_015247290.1\|4926280_4927540_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|372616
NC_019892.1\|WP_026012165.1\|4938242_4939622_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237865
NC_019892.1\|WP_015247299.1\|4937505_4938150_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274375
NC_019892.1\|WP_015247286.1\|4921776_4922754_+\|GDP-mannose-4,6-dehydratase	unknown	unknown	gnl\|CDD\|187562
NC_019892.1\|WP_015247291.1\|4927536_4929348_+\|thiamine-pyrophosphate-binding-protein	unknown	unknown	gnl\|CDD\|223107
NC_019892.1\|WP_020467356.1\|4932511_4933567_+\|flippase-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|377103
NC_019892.1\|WP_015247297.1\|4934851_4936261_+\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238017
NC_019892.1\|WP_015247288.1\|4924070_4925144_+\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223528
NC_019892.1\|WP_015247301.1\|4939733_4940777_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247299.1\|4937505_4938150_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274375	TIGR02984, Sig-70_plancto1, RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are apparently found only in the Planctomycetaceae family including the genuses Gemmata and Pirellula (in which seven sequences are found).	6.3628e-38
NC_019892.1\|WP_015247294.1\|4930914_4932006_+\|3-dehydroquinate-synthase	gnl\|CDD\|275218	TIGR04425, 3-dehydroquinate_synthase, putative sugar phosphate phospholyase (cyclizing). Members of this family tend to be found in O-antigen biosynthesis regions. Members frequently are misidentified as the closely related 3-dehydroquinate synthase, AroB (see family TIGR01357), the phospholyase that converts 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate to 3-dehydroquinate during chorismate biosynthesis. Most bacteria with this enzyme have a true AroB in a chorismate biosynthesis gene cluster. [Biosynthesis of cofactors, prosthetic groups, and carriers, Lipoate].	0
NC_019892.1\|WP_015247285.1\|4921000_4921780_+\|glucose-1-phosphate-cytidylyltransferase	gnl\|CDD\|133015	cd02524, G1P_cytidylyltransferase, G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose. Alpha-D-Glucose-1-phosphate Cytidylyltransferase catalyzes the production of CDP-D-Glucose from alpha-D-Glucose-1-phosphate and MgCTP as substrate. CDP-D-Glucose is the precursor for synthesizing four of the five naturally occurring 3,6-dideoxy sugars-abequose (3,6-dideoxy-D-Xylo-hexose), ascarylose (3,6-dideoxy-L-arabino-hexose), paratose (3,6-dideoxy-D-ribohexose), and tyvelose (3,6-dideoxy-D-arabino-hexose. Deoxysugars are ubiquitous in nature where they function in a variety of biological processes, including cell adhesion, immune response, determination of ABO blood groups, fertilization, antibiotic function, and microbial pathogenicity.	5.26378e-148
NC_019892.1\|WP_015247302.1\|4941364_4941694_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.05724e-18
NC_019892.1\|WP_015247293.1\|4930202_4930874_+\|SDR-family-oxidoreductase	gnl\|CDD\|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	3.08815e-70
NC_019892.1\|WP_015247289.1\|4925151_4926234_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	1.30711e-69
NC_019892.1\|WP_015247287.1\|4922746_4924078_+\|lipopolysaccharide-biosynthesis-protein-RfbH	gnl\|CDD\|237960	PRK15407, PRK15407, lipopolysaccharide biosynthesis protein RfbH; Provisional.	0
NC_019892.1\|WP_015247296.1\|4933561_4934242_-\|HAD-family-hydrolase	gnl\|CDD\|319806	cd07503, HAD_HisB-N, histidinol phosphate phosphatase and related phosphatases. This family includes the N-terminal domain of the Escherichia coli bifunctional enzyme histidinol-phosphate phosphatase/imidazole-glycerol-phosphate dehydratase, HisB. The N-terminal histidinol-phosphate phosphatase domain catalyzes the dephosphorylation of histidinol phosphate, the eight step of L-histidine biosynthesis. This family also includes Escherichia coli GmhB phosphatase which is highly specific for D-glycero-D-manno-heptose-1,7-bisphosphate, it removes the C(7)phosphate and not the C(1)phosphate, and this is the third essential step of lipopolysaccharide heptose biosynthesis. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.03311e-57
NC_019892.1\|WP_026012166.1\|4943569_4944214_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274375	TIGR02984, Sig-70_plancto1, RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are apparently found only in the Planctomycetaceae family including the genuses Gemmata and Pirellula (in which seven sequences are found).	1.3351e-47
NC_019892.1\|WP_015247292.1\|4929394_4930210_+\|hypothetical-protein	gnl\|CDD\|226356	COG3836, HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism].	4.15062e-05
NC_019892.1\|WP_015247290.1\|4926280_4927540_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|372616	pfam13489, Methyltransf_23, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.71976e-21
NC_019892.1\|WP_026012165.1\|4938242_4939622_-\|hypothetical-protein	gnl\|CDD\|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	5.3809e-07
NC_019892.1\|WP_015247286.1\|4921776_4922754_+\|GDP-mannose-4,6-dehydratase	gnl\|CDD\|187562	cd05252, CDP_GD_SDR_e, CDP-D-glucose 4,6-dehydratase, extended (e) SDRs. This subgroup contains CDP-D-glucose 4,6-dehydratase, an extended SDR, which catalyzes the conversion of CDP-D-glucose to CDP-4-keto-6-deoxy-D-glucose. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.14671e-131
NC_019892.1\|WP_015247291.1\|4927536_4929348_+\|thiamine-pyrophosphate-binding-protein	gnl\|CDD\|223107	COG0028, IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism].	2.195e-145
NC_019892.1\|WP_020467356.1\|4932511_4933567_+\|flippase-like-domain-containing-protein	gnl\|CDD\|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	3.2043e-16
NC_019892.1\|WP_015247297.1\|4934851_4936261_+\|FHA-domain-containing-protein	gnl\|CDD\|238017	cd00060, FHA, Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).	1.66765e-09
NC_019892.1\|WP_015247288.1\|4924070_4925144_+\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	1.43366e-43
NC_019892.1\|WP_015247301.1\|4939733_4940777_-\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	0.000383876

>NC_019892.1|WP_015247294.1|4930914_4932006_+|3-dehydroquinate-synthase
MLEVVSSSGRYRVDAVDTVAEAIAAALESSSAGGGFVLADATVVSLHPDAFGQVADSSSRLLVIEASEEAKSYAAIEPIIEALIQAGIKRNSTLIVVGGGVLQDIGCFIASVLFRGIAWSLVPSTLLAQCDSCIGSKSSINVGRFKNQLGTFHAPKQVYLVFDLLRTLPHDEIRSGMGEIIKLHLVAGENELARLKTHLAHYAATGEGLDQLVWDALRIKKGFIEQDEFDTGRRNLLNYGHTFGHAYESATQYGIPHGIAVSLGISTATFFSEQLSLAPAGAADAIDELLKPWYQPYERVLHQADRQAVFAAMKLDKKNTGASVTCILTRGPGQMEKVPLDANAQVFELLSKYYERISIPNNL
>NC_019892.1|WP_015247293.1|4930202_4930874_+|SDR-family-oxidoreductase
MHKHKALVTGGSRGIGAEIAIALRCGGVEVITPSRSELDLLDPVSIDRYIEAHHDDGIDILVNNAGINPIAALEAVSAEDWARTLQVNLTAPFRLIQGFSPGMKSAGWGRVVNVSSIWAVASKGGRASYSSAKSGLIGLTRTTALELAPHGVLVNAVCPGYVETELTRANNTPEQLAAIRGTIPVGRLAQPEEIARFVAFLCSTDNTYLVGQALVIDGGFTCQ
>NC_019892.1|WP_015247292.1|4929394_4930210_+|hypothetical-protein
MNSLEKQMIERLVELRERYHVTGVKAEFEAEGTRMEEAMRLKDVSAQAGVGMNIKIGGCEALKDMFDAISLGVERIIAPMVETPYALQKFLGAAKLAFGDDHEVELLINIETLTSVENFEAMLRIPQIDHLHGVVIGRVDLSGSMGLARDQINNDEILRLSLQVAKLAKEAGKSVVVGGGVSAHSLPFFRDFPQGHLDRFETRKVIFSCPGALANPEEAFLKAVEFELLWLRNKKAYYGAIHREDDGRLAMMEKRYQDSINMVNQKRPGHA
>NC_019892.1|WP_015247291.1|4927536_4929348_+|thiamine-pyrophosphate-binding-protein
MIRVADYIARTLFEHGIEHVFMVTGGGAMHLNDAIGRCDGLKYICCHHEQACTMAADSYFRLTNRLAAVNVTTGPGGTNAITGVFGAWTDSLGMVVVSGQVKWETLVRSTGLPLRQLGDQEVDIIRLVEPITKYAVMVTEPTSIRYHLERALHLARSGRPGPVWLDVPINVQGAIVDETALPGYDPQEDRIAFTSDLDGACRDVLTRLKQAERPVIMAGSGVRLAGAGAREDFLQLVEALGVPVTTSWNAHDVIWNEHPCYVGRPGTIGDRAGNFAVQNADFLLVLGCRLNIRQISYDWKKFARAADLVMVDVDANELKKPTLSPSLAIHADLADFLPRLLALVHEEPPPSHSAWLAWGRERARRYPAVLPEYWETEAGVNPYCFVDVLFDQLPADQIVVTGDGTACVVTFQAAKIQEHQRLYTNSGCASMGYDLPAAIGACLASGGRPVVCLAGDGSIQMNLQELQTIVGRGLPIKLFVLNNQGYHSIRQTQQNYFADNIVGCGLDSGLSFPDFGRLATAYGIPYRRVDRHGDLATAVAETLAGPGPQVCEVMLDLAQAFAPKLASKKLADGRMVSAPLEDLTPLLSREEFAENMIIPPLAE
>NC_019892.1|WP_015247290.1|4926280_4927540_+|methyltransferase-domain-containing-protein
MAQSSLRSEAGSAPPDRPCPVCDGGECAVMHTQRFVLPEDHPLRDGYKVVCCDRCGFVYASTPANQADYDAFYAKFSKYEDNTTSTGSGVTPWDAERLEGTAADLARFIPDRAARIVDIGCANGGLLAALKARGYENLCGVDPSPGCARYVRDQLGIEAYPGLLTRLPDELGSVDAVLLSHVMEHVRELRPALEAVRRVMKPGAILYVEVPDATRYVDFLFAPFQDFNTEHINHFSHDSLANLLRACGLQPVESGRRMLMTSPGMPYPAIYAVGVGSAANLPVPAEAVRKDQTLRPAIEAYIAGSARLLAAIDLKIRRALESSGPILVWGAGQLAMKLLAETSLGQAEIAAFVDGNPIHHGKTIRGVPVLAPEQVRGLAHPILITSTLHEREIVEKISQMGLNHRVLCLGAESDVRNSS
>NC_019892.1|WP_015247289.1|4925151_4926234_+|glycosyltransferase-family-2-protein
MHADQDSGVAQGQRKHICVVSPCYNEVENVRELYEAIKLVFAELPQYRYSHLYIDNASTDGTVAILRELAHADPNVKVIVNARNFGHIRSPFHAMLQSDGDATILMASDFQDPPSMIPDFIKRWEEGSKIIIGVKVESDEQPLMYALRSMYYGLAAKLADIELMQHVTGFGLYDQRVIEILREIDDPHPYFRGLIADIGLDCCKIPYRQPQRRRGITKNNFYSLYDIAMLGITNHSKVPLRVATIAGFMMSAVCLLLAIGYFIAKLLFWNWFSVGVAPILISLLLFSSVQLFFIGIIGEYIGAIHTQVQKRPLVIEKERLNFEGPPPESRANDGNRRRYVYAVQDGPPMPSPLDWEKAGS
>NC_019892.1|WP_015247288.1|4924070_4925144_+|NAD(P)-dependent-oxidoreductase
MANPLADDLDHVLAQVDPLWEDLRGARLFLTGGTGFFGCWLLESLLWADAHRRLGVEVVVLTRSPAAFARKAPHLAGHRAVRLYEGDVRSFADPEGTFTHVIHAATEASAALNAEAPRIMFETIVEGTRRTLDLARRSGASRFLLTSSGAVYGSQPATLTHVGEDYPGAPDPTDPRSAYGEGKRVAEHLAALECHAHGLGAVIARCFAFVGPYLPLDIHFAVGNFVRDALAGGPVRVAGDGTPWRSYQYAADLMVWLWSILLRGVPGRSYNVGSEEALTIGDVARRIAEAEGVAWGIDREPIAGALATRYVPSTARARDELGLACPIGFDDAIARTVRWHRNRIRNLVDCPSPSLVP
>NC_019892.1|WP_015247287.1|4922746_4924078_+|lipopolysaccharide-biosynthesis-protein-RfbH
MNENESSENLRRQILDLVRRYHTAAFPTRPFTPGESALACAGRVFDDEELVHLVDSSLDFWLTTGRFAEQFEREFAARFGVRHALLVNSGSSANLVALSCLTSPKLGERRLRAGDEVITVAAGFPTTVNPIIQNHLVPVFVDVQIPTYNIDPTQLEPALSSRTRAIMIAHTLGNPFDLNAVTAFAREHNLWLIEDCCDAVGSTYDGKNVGTFGDLATVSFYPAHHITMGEGGAVLTDRPRLKTLVESFRDWGRDCWCAPGMDNTCGKRFDWQLGELPPGYDHKYIYSHIGYNLKLTDMQAAVGVAQLAKLDGFVAARRDNFRRLRNGLTGLEEFLVLPEATPGSDPSWFGFPLAVRPGAPFTRRELVNFLNGRKIATRLVFAGNLLRQPAYVEIEHRTIGDLANTDFVMNQALWVGVYPGLSAAMIDSMIASLEDFCREAVHG
>NC_019892.1|WP_015247286.1|4921776_4922754_+|GDP-mannose-4,6-dehydratase
MSKFWLDRPTLVTGATGLVGGWLVTRLLDAGADVTCLVRDWVPQSGLIRDRLVDRVKVVRGDIRDQGLLERALGEHEINTVFHLAAQTIVGTANRNPVSTFESNIQGTWALLEACRRSPAVKQVVLASSDKAYGDQEQLPYDESTPLQGQHPYDVSKSCADLIAHSYAVSYKLPVAITRCGNFYGGGDLNWNRIVPGTIRSVIRGQRPVIRSDGKFVRDYFYVEDGANAYLVLAEALADRPELAGAAYNFSNEVQVTVLDLVRAILRAMGSDLEPEIRNEASNEIIHQYLSAAKARRELAWAPLFDLDEGMARTIRWYRDFFSHE
>NC_019892.1|WP_015247285.1|4921000_4921780_+|glucose-1-phosphate-cytidylyltransferase
MKVLILCGGQGTRLREETEFRPKPLVEIGQRPILWHIMKLFAHHGFREFVLCLGYRGKMIKDYFLNYEAMNNDFTICLGQRHSVTLHDAHEEQDFRVTLADTGEETMTGGRIQRAARYLDGDTFMVTYGDGVANVDITRLLAFHKSHGRMATVTAIRPYSRFGALEVDSADRVVNFAEKPQIEGWSSAGFFVFNRKLLDYLDGDSCILEREPLERVTQQGELMIYRHEGFFFAMDTYREYKALNDLWDSGQAPWKVWEK
>NC_019892.1|WP_020467356.1|4932511_4933567_+|flippase-like-domain-containing-protein
MIDDAILGTVSAVPDSNPPRKGLKRLLRVASYGLGFGLLGWALWRNQGSVREVIGRRPNLYDLALALVLGEIALLSTFARWYLLARVQGVPLTFRQAVRIGFLGHASELVVPGQLGGDVVKVAAFCRGEGEGRQDRKRAPGIASVLFDRVTGVFGLFLLVSLMGTLQWSTAAVAVRRLIEVVWLVTGAGLIGFAVLFLPATAVFLRRILGEGGLPGKLAGLWDAAAAYRGHPLAVVMALAMAMASHAFYAFSFYAVIRALFPIAPPLTTSLVIIPLILFTAIVPLPFGALGVGEEVSGELFRMIGHSIGTPAMLGARCVGLGLSCLSVLISLSSTRGPLAPERQAEGPDPS
>NC_019892.1|WP_015247296.1|4933561_4934242_-|HAD-family-hydrolase
MVTRRDFPLTGKEEPQSHRNPARSISAAAPFERPSVPGGKPAVFLDRDGTIIEHVHYLSDVRQVRLLPGAAEAIGRLRAAGFACVVVTNQSAVGRGMITEAQLGLIHDEMNRQLADAGTAVDAIEFCPEPPAIADRSRIEHIDRKPGPGMLFRATHALGLDLDASWMIGDMLSDVLAGVNAGCRGSILVQTGKGLDEAEKETAAAFHVTEDLAAAADLILAPSLLS
>NC_019892.1|WP_015247297.1|4934851_4936261_+|FHA-domain-containing-protein
MNPTSNETLSTFSESCGAGALQLNVLAGEGSPGTQRSFDQPFLVVGRSPDADLRIDSDQVSARHCYLQVIGGRLVSIDLDGQGGVLIDGTPQRFGWVTPVTQLQIGPAVFRVQGEGEGGEPRLHPLSTLYARTLPTTALEIDGVVGQTYGWRMSRALALIGRSTACQVRLMNPSISNFHAALVRTPSGVWIVDLLSREGLEVDGAYVRAARLEEGSACRLGTFTLRFCRGTLAPTPPRRSEVSRLLSAPASSAPQAANSAERSVLLAAPTTAETLFSLAATRSSNPAGGESTLRPTWNPLEPALDAPQQSIMMLLAQMLGTMHRDHMDLVKDELVEIRRLAEEMHALRVEIGQRPATEPAAPVPPEVTAAPAKGPVVEPVAIGPAAPADAARVAGNAGPGPGPGAGANRGEEAASVPRDPRECLAIASRFLASYERKQEGHWSRILRVLTGASRNQDPGRGPLEQAPLG
>NC_019892.1|WP_015247298.1|4936661_4937126_+|hypothetical-protein
MTVSRKVLSLAVLVGGWSILSPTFAEAKTRPNVKNQKALRALVSARQTESLSPDLGFGSVTLPLNQRQVNQFLNNYFRQPNARISASLRANPYSAEANARRAFALEVFRERAMLKISGIAGGVFFSPPAGTPYYPVAANNFLQRLPIFRVLGIF
>NC_019892.1|WP_015247299.1|4937505_4938150_+|sigma-70-family-RNA-polymerase-sigma-factor
MDNEKRHEIKVMVDVTVESLIEDARGGAQKSLGDALEALRPYLVRIAMNELAPDLRPKGDVSDLVQETFLEAARDFGNFTGRTGPEWRSWLRRIFFNNLNLLARTYRNTIKRDVGVEVSLDQVKAAGVNDHNLVLSGSSPSSVVMKKEMGEVIQDALTQLTDRERQLLIMRFREQCTFEEMGRRLGYSPVAARKALRKAVARVREQVDFSSMAG
>NC_019892.1|WP_026012165.1|4938242_4939622_-|hypothetical-protein
MLLVLLWPVLVIGGEPTAGEKAAAVIPDPDYVPKVGDRAVLYSLDSEKIPFDLWCASTSPDCRNFIKSMLAPDDENQAAGDPAAEAKLVHLAPKTDVQLLAVETVEVAGAKEGPPLKCTYFAIKVLAGPFQGQTLYTLDFHITRLIPPPAPLGVGAETEAPKTLAAAPAPAPTRIELEIVDAPASPREKTKGPETPALVSAPTPIERETTDIPVTNQERGKLPLAPARIERETTAKPGRATASGAPAIATQAPRPEASSPARPVAFASTAPVILDTSSPSAPSPSLLPRADVVTRESSQPASPAPGDASTSQRTGIGGPQPARRSLPNPARALVSAPTKPLSAPELLTMAQERDAAGKAVEALVAYRTLERTHPGSQETRIAVGRIKGLTERLEVDAQEVRAGLLMKQARTIEASGNRELASGYFQQIVRVYPKTPTARLAAERIKTMGTSRPTPAPAP
>NC_019892.1|WP_015247301.1|4939733_4940777_-|hypothetical-protein
MGATVPRHALIFRVHRLALAGMTGAWLVAGMLCAGPARAGEPGGALAGSSPSPKQPPQANASLPVSAARRSPHQAYLFFSGSKRPPQHPAGAEKGQTAAGPLVEAQRPAYLFFTPGKKTPPITPAPVDERRPSYRFFTPEKKKTAQTPTTAPATGQVPPGPPPTPGSGLDPSSKRPALALKAAVAGDGLPLTPPQPRLLFFAPKRGAANANAGHSPATNQTARPEGRKPTMLAAIERVPVRLPGTPAQNRNPPPYLIFQPKPKPVRDRLSPAPKANGTSSSATTPPRQGGTAVARTPWPAARREFPGFDLVPTLTLADLPRLRFAPITAPAVGSGSGGGNQPAPRLR
>NC_019892.1|WP_015247302.1|4941364_4941694_+|winged-helix-turn-helix-transcriptional-regulator
MPSARSAAAKARVKKDAEQRFKRAQRASILLKHVSDATRLQVILLLADGERHVGDLSESLNQSQPAVSHHLALMRHGGIVVPRRQGKNNYYSLTDSGEILAKVVQAMTS
>NC_019892.1|WP_015247303.1|4943172_4943523_+|hypothetical-protein
MPPRPHIMTFRQLEESRAALDSDVQVVSRSEVSRPLLNGASVDCRSGDAACLTPKGRALIFSIVVVEAIVFLAIAITSLQGPADLSHSAWVLATLSLLFLALSQLRRWVTRRLLED
>NC_019892.1|WP_026012166.1|4943569_4944214_-|sigma-70-family-RNA-polymerase-sigma-factor
MTNSSETELLLARASAGDNRALADLFEHYRERLERMVRLRLDRRLQGRLDPADVLQEVYLELAKRYPDYAAEASLPFYLWLRMLTGQKLVDQHRRHLGAKMRDAGMEVSLHRAGMPQASSASLAEMLLGRLTSASRVAIRTETRIRVQEALNTMDPIDREVLVLRHFEMLSNEETARVLNLKTSAASNRHLRALKRLKEILAETPLVDDRSAPR

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Crispr_ID: NC_019892_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_9

4938920-4939015

Orphan

Consensus_repeat	Method
CCGTGGTTTCGCGCTCGATGCGCG	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_019892_9

>merge|NC_019892|9|4938920-4939015|CRISPRCasFinder
CCGTGGTTTCGCGCTCGATGCGCGCGGGTGCGAGGGGAAGTTTGCCCCTTTCTTGATTCGTGACAGGAATGTCCGTGGTTTCGCGCTCGATGGGCG

>NC_019892|9|8|4938920-4939015|CRISPRCasFinder
CCGTGGTTTCGCGCTCGATGCGCG	CGGGTGCGAGGGGAAGTTTGCCCCTTTCTTGATTCGTGACAGGAATGT
CCGTGGTTTCGCGCTCGATGGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015247306.1\|4945848_4946244_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247299.1\|4937505_4938150_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274375
NC_019892.1\|WP_015247294.1\|4930914_4932006_+\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|275218
NC_019892.1\|WP_015247307.1\|4946299_4951402_-\|protein-kinase	unknown	unknown	gnl\|CDD\|238121
NC_019892.1\|WP_015247310.1\|4954600_4957387_-\|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223972
NC_019892.1\|WP_015247297.1\|4934851_4936261_+\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238017
NC_019892.1\|WP_015247303.1\|4943172_4943523_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247293.1\|4930202_4930874_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187594
NC_019892.1\|WP_015247296.1\|4933561_4934242_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319806
NC_019892.1\|WP_026012166.1\|4943569_4944214_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274375
NC_019892.1\|WP_015247292.1\|4929394_4930210_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226356
NC_019892.1\|WP_015247290.1\|4926280_4927540_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|372616
NC_019892.1\|WP_015247309.1\|4953117_4954500_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247308.1\|4951618_4952905_-\|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379079
NC_019892.1\|WP_015247305.1\|4944683_4945736_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015247291.1\|4927536_4929348_+\|thiamine-pyrophosphate-binding-protein	unknown	unknown	gnl\|CDD\|223107
NC_019892.1\|WP_020467356.1\|4932511_4933567_+\|flippase-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|377103
NC_019892.1\|WP_015247298.1\|4936661_4937126_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247302.1\|4941364_4941694_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NC_019892.1\|WP_015247301.1\|4939733_4940777_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247299.1\|4937505_4938150_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274375	TIGR02984, Sig-70_plancto1, RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are apparently found only in the Planctomycetaceae family including the genuses Gemmata and Pirellula (in which seven sequences are found).	6.3628e-38
NC_019892.1\|WP_015247294.1\|4930914_4932006_+\|3-dehydroquinate-synthase	gnl\|CDD\|275218	TIGR04425, 3-dehydroquinate_synthase, putative sugar phosphate phospholyase (cyclizing). Members of this family tend to be found in O-antigen biosynthesis regions. Members frequently are misidentified as the closely related 3-dehydroquinate synthase, AroB (see family TIGR01357), the phospholyase that converts 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate to 3-dehydroquinate during chorismate biosynthesis. Most bacteria with this enzyme have a true AroB in a chorismate biosynthesis gene cluster. [Biosynthesis of cofactors, prosthetic groups, and carriers, Lipoate].	0
NC_019892.1\|WP_015247307.1\|4946299_4951402_-\|protein-kinase	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	5.02575e-84
NC_019892.1\|WP_015247310.1\|4954600_4957387_-\|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase	gnl\|CDD\|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	0
NC_019892.1\|WP_015247297.1\|4934851_4936261_+\|FHA-domain-containing-protein	gnl\|CDD\|238017	cd00060, FHA, Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).	1.66765e-09
NC_019892.1\|WP_015247293.1\|4930202_4930874_+\|SDR-family-oxidoreductase	gnl\|CDD\|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	3.08815e-70
NC_019892.1\|WP_015247296.1\|4933561_4934242_-\|HAD-family-hydrolase	gnl\|CDD\|319806	cd07503, HAD_HisB-N, histidinol phosphate phosphatase and related phosphatases. This family includes the N-terminal domain of the Escherichia coli bifunctional enzyme histidinol-phosphate phosphatase/imidazole-glycerol-phosphate dehydratase, HisB. The N-terminal histidinol-phosphate phosphatase domain catalyzes the dephosphorylation of histidinol phosphate, the eight step of L-histidine biosynthesis. This family also includes Escherichia coli GmhB phosphatase which is highly specific for D-glycero-D-manno-heptose-1,7-bisphosphate, it removes the C(7)phosphate and not the C(1)phosphate, and this is the third essential step of lipopolysaccharide heptose biosynthesis. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.03311e-57
NC_019892.1\|WP_026012166.1\|4943569_4944214_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274375	TIGR02984, Sig-70_plancto1, RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are apparently found only in the Planctomycetaceae family including the genuses Gemmata and Pirellula (in which seven sequences are found).	1.3351e-47
NC_019892.1\|WP_015247302.1\|4941364_4941694_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.05724e-18
NC_019892.1\|WP_015247290.1\|4926280_4927540_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|372616	pfam13489, Methyltransf_23, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.71976e-21
NC_019892.1\|WP_015247308.1\|4951618_4952905_-\|right-handed-parallel-beta-helix-repeat-containing-protein	gnl\|CDD\|379079	pfam13229, Beta_helix, Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.	1.82189e-06
NC_019892.1\|WP_015247305.1\|4944683_4945736_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	7.15151e-41
NC_019892.1\|WP_015247291.1\|4927536_4929348_+\|thiamine-pyrophosphate-binding-protein	gnl\|CDD\|223107	COG0028, IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism].	2.195e-145
NC_019892.1\|WP_020467356.1\|4932511_4933567_+\|flippase-like-domain-containing-protein	gnl\|CDD\|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	3.2043e-16
NC_019892.1\|WP_015247292.1\|4929394_4930210_+\|hypothetical-protein	gnl\|CDD\|226356	COG3836, HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism].	4.15062e-05
NC_019892.1\|WP_015247301.1\|4939733_4940777_-\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	0.000383876

>NC_019892.1|WP_015247299.1|4937505_4938150_+|sigma-70-family-RNA-polymerase-sigma-factor
MDNEKRHEIKVMVDVTVESLIEDARGGAQKSLGDALEALRPYLVRIAMNELAPDLRPKGDVSDLVQETFLEAARDFGNFTGRTGPEWRSWLRRIFFNNLNLLARTYRNTIKRDVGVEVSLDQVKAAGVNDHNLVLSGSSPSSVVMKKEMGEVIQDALTQLTDRERQLLIMRFREQCTFEEMGRRLGYSPVAARKALRKAVARVREQVDFSSMAG
>NC_019892.1|WP_015247298.1|4936661_4937126_+|hypothetical-protein
MTVSRKVLSLAVLVGGWSILSPTFAEAKTRPNVKNQKALRALVSARQTESLSPDLGFGSVTLPLNQRQVNQFLNNYFRQPNARISASLRANPYSAEANARRAFALEVFRERAMLKISGIAGGVFFSPPAGTPYYPVAANNFLQRLPIFRVLGIF
>NC_019892.1|WP_015247297.1|4934851_4936261_+|FHA-domain-containing-protein
MNPTSNETLSTFSESCGAGALQLNVLAGEGSPGTQRSFDQPFLVVGRSPDADLRIDSDQVSARHCYLQVIGGRLVSIDLDGQGGVLIDGTPQRFGWVTPVTQLQIGPAVFRVQGEGEGGEPRLHPLSTLYARTLPTTALEIDGVVGQTYGWRMSRALALIGRSTACQVRLMNPSISNFHAALVRTPSGVWIVDLLSREGLEVDGAYVRAARLEEGSACRLGTFTLRFCRGTLAPTPPRRSEVSRLLSAPASSAPQAANSAERSVLLAAPTTAETLFSLAATRSSNPAGGESTLRPTWNPLEPALDAPQQSIMMLLAQMLGTMHRDHMDLVKDELVEIRRLAEEMHALRVEIGQRPATEPAAPVPPEVTAAPAKGPVVEPVAIGPAAPADAARVAGNAGPGPGPGAGANRGEEAASVPRDPRECLAIASRFLASYERKQEGHWSRILRVLTGASRNQDPGRGPLEQAPLG
>NC_019892.1|WP_015247296.1|4933561_4934242_-|HAD-family-hydrolase
MVTRRDFPLTGKEEPQSHRNPARSISAAAPFERPSVPGGKPAVFLDRDGTIIEHVHYLSDVRQVRLLPGAAEAIGRLRAAGFACVVVTNQSAVGRGMITEAQLGLIHDEMNRQLADAGTAVDAIEFCPEPPAIADRSRIEHIDRKPGPGMLFRATHALGLDLDASWMIGDMLSDVLAGVNAGCRGSILVQTGKGLDEAEKETAAAFHVTEDLAAAADLILAPSLLS
>NC_019892.1|WP_020467356.1|4932511_4933567_+|flippase-like-domain-containing-protein
MIDDAILGTVSAVPDSNPPRKGLKRLLRVASYGLGFGLLGWALWRNQGSVREVIGRRPNLYDLALALVLGEIALLSTFARWYLLARVQGVPLTFRQAVRIGFLGHASELVVPGQLGGDVVKVAAFCRGEGEGRQDRKRAPGIASVLFDRVTGVFGLFLLVSLMGTLQWSTAAVAVRRLIEVVWLVTGAGLIGFAVLFLPATAVFLRRILGEGGLPGKLAGLWDAAAAYRGHPLAVVMALAMAMASHAFYAFSFYAVIRALFPIAPPLTTSLVIIPLILFTAIVPLPFGALGVGEEVSGELFRMIGHSIGTPAMLGARCVGLGLSCLSVLISLSSTRGPLAPERQAEGPDPS
>NC_019892.1|WP_015247294.1|4930914_4932006_+|3-dehydroquinate-synthase
MLEVVSSSGRYRVDAVDTVAEAIAAALESSSAGGGFVLADATVVSLHPDAFGQVADSSSRLLVIEASEEAKSYAAIEPIIEALIQAGIKRNSTLIVVGGGVLQDIGCFIASVLFRGIAWSLVPSTLLAQCDSCIGSKSSINVGRFKNQLGTFHAPKQVYLVFDLLRTLPHDEIRSGMGEIIKLHLVAGENELARLKTHLAHYAATGEGLDQLVWDALRIKKGFIEQDEFDTGRRNLLNYGHTFGHAYESATQYGIPHGIAVSLGISTATFFSEQLSLAPAGAADAIDELLKPWYQPYERVLHQADRQAVFAAMKLDKKNTGASVTCILTRGPGQMEKVPLDANAQVFELLSKYYERISIPNNL
>NC_019892.1|WP_015247293.1|4930202_4930874_+|SDR-family-oxidoreductase
MHKHKALVTGGSRGIGAEIAIALRCGGVEVITPSRSELDLLDPVSIDRYIEAHHDDGIDILVNNAGINPIAALEAVSAEDWARTLQVNLTAPFRLIQGFSPGMKSAGWGRVVNVSSIWAVASKGGRASYSSAKSGLIGLTRTTALELAPHGVLVNAVCPGYVETELTRANNTPEQLAAIRGTIPVGRLAQPEEIARFVAFLCSTDNTYLVGQALVIDGGFTCQ
>NC_019892.1|WP_015247292.1|4929394_4930210_+|hypothetical-protein
MNSLEKQMIERLVELRERYHVTGVKAEFEAEGTRMEEAMRLKDVSAQAGVGMNIKIGGCEALKDMFDAISLGVERIIAPMVETPYALQKFLGAAKLAFGDDHEVELLINIETLTSVENFEAMLRIPQIDHLHGVVIGRVDLSGSMGLARDQINNDEILRLSLQVAKLAKEAGKSVVVGGGVSAHSLPFFRDFPQGHLDRFETRKVIFSCPGALANPEEAFLKAVEFELLWLRNKKAYYGAIHREDDGRLAMMEKRYQDSINMVNQKRPGHA
>NC_019892.1|WP_015247291.1|4927536_4929348_+|thiamine-pyrophosphate-binding-protein
MIRVADYIARTLFEHGIEHVFMVTGGGAMHLNDAIGRCDGLKYICCHHEQACTMAADSYFRLTNRLAAVNVTTGPGGTNAITGVFGAWTDSLGMVVVSGQVKWETLVRSTGLPLRQLGDQEVDIIRLVEPITKYAVMVTEPTSIRYHLERALHLARSGRPGPVWLDVPINVQGAIVDETALPGYDPQEDRIAFTSDLDGACRDVLTRLKQAERPVIMAGSGVRLAGAGAREDFLQLVEALGVPVTTSWNAHDVIWNEHPCYVGRPGTIGDRAGNFAVQNADFLLVLGCRLNIRQISYDWKKFARAADLVMVDVDANELKKPTLSPSLAIHADLADFLPRLLALVHEEPPPSHSAWLAWGRERARRYPAVLPEYWETEAGVNPYCFVDVLFDQLPADQIVVTGDGTACVVTFQAAKIQEHQRLYTNSGCASMGYDLPAAIGACLASGGRPVVCLAGDGSIQMNLQELQTIVGRGLPIKLFVLNNQGYHSIRQTQQNYFADNIVGCGLDSGLSFPDFGRLATAYGIPYRRVDRHGDLATAVAETLAGPGPQVCEVMLDLAQAFAPKLASKKLADGRMVSAPLEDLTPLLSREEFAENMIIPPLAE
>NC_019892.1|WP_015247290.1|4926280_4927540_+|methyltransferase-domain-containing-protein
MAQSSLRSEAGSAPPDRPCPVCDGGECAVMHTQRFVLPEDHPLRDGYKVVCCDRCGFVYASTPANQADYDAFYAKFSKYEDNTTSTGSGVTPWDAERLEGTAADLARFIPDRAARIVDIGCANGGLLAALKARGYENLCGVDPSPGCARYVRDQLGIEAYPGLLTRLPDELGSVDAVLLSHVMEHVRELRPALEAVRRVMKPGAILYVEVPDATRYVDFLFAPFQDFNTEHINHFSHDSLANLLRACGLQPVESGRRMLMTSPGMPYPAIYAVGVGSAANLPVPAEAVRKDQTLRPAIEAYIAGSARLLAAIDLKIRRALESSGPILVWGAGQLAMKLLAETSLGQAEIAAFVDGNPIHHGKTIRGVPVLAPEQVRGLAHPILITSTLHEREIVEKISQMGLNHRVLCLGAESDVRNSS
>NC_019892.1|WP_015247301.1|4939733_4940777_-|hypothetical-protein
MGATVPRHALIFRVHRLALAGMTGAWLVAGMLCAGPARAGEPGGALAGSSPSPKQPPQANASLPVSAARRSPHQAYLFFSGSKRPPQHPAGAEKGQTAAGPLVEAQRPAYLFFTPGKKTPPITPAPVDERRPSYRFFTPEKKKTAQTPTTAPATGQVPPGPPPTPGSGLDPSSKRPALALKAAVAGDGLPLTPPQPRLLFFAPKRGAANANAGHSPATNQTARPEGRKPTMLAAIERVPVRLPGTPAQNRNPPPYLIFQPKPKPVRDRLSPAPKANGTSSSATTPPRQGGTAVARTPWPAARREFPGFDLVPTLTLADLPRLRFAPITAPAVGSGSGGGNQPAPRLR
>NC_019892.1|WP_015247302.1|4941364_4941694_+|winged-helix-turn-helix-transcriptional-regulator
MPSARSAAAKARVKKDAEQRFKRAQRASILLKHVSDATRLQVILLLADGERHVGDLSESLNQSQPAVSHHLALMRHGGIVVPRRQGKNNYYSLTDSGEILAKVVQAMTS
>NC_019892.1|WP_015247303.1|4943172_4943523_+|hypothetical-protein
MPPRPHIMTFRQLEESRAALDSDVQVVSRSEVSRPLLNGASVDCRSGDAACLTPKGRALIFSIVVVEAIVFLAIAITSLQGPADLSHSAWVLATLSLLFLALSQLRRWVTRRLLED
>NC_019892.1|WP_026012166.1|4943569_4944214_-|sigma-70-family-RNA-polymerase-sigma-factor
MTNSSETELLLARASAGDNRALADLFEHYRERLERMVRLRLDRRLQGRLDPADVLQEVYLELAKRYPDYAAEASLPFYLWLRMLTGQKLVDQHRRHLGAKMRDAGMEVSLHRAGMPQASSASLAEMLLGRLTSASRVAIRTETRIRVQEALNTMDPIDREVLVLRHFEMLSNEETARVLNLKTSAASNRHLRALKRLKEILAETPLVDDRSAPR
>NC_019892.1|WP_015247305.1|4944683_4945736_+|DUF1559-domain-containing-protein
MLRRTRSAFTLIELLVVIAIIAVLIALLLPAVQAAREAARRSQCVNNLKQLGIALHNYHDTVGCLPMGAFDMTHGCQQYSPLTMLLPQLEQNAIYNSMNYANISGACWQILYNQTGFRSSVNVFLCPSDVDRITTIEGHSNYCANWGSKPYRYSANPNGPFFTTDFTSLGGWKGGIPKPLTLAGVLDGTSNTAGFSERNKGIGDGHTLGTSMALDPTTPSATPFNLSGPSDDPATDTTVQTYYANCKALAPIASNISNTGVPGGEWHQMLMGDTCYTHVMPPNSLTCVYPAGTDKNHPQGALTATSRHSGVVNVLFLDGTVRAVKSTIAPATWWAIGTSASSEVVSADAL
>NC_019892.1|WP_015247306.1|4945848_4946244_+|hypothetical-protein
MRRFVLPSGVAGRAAALMTVLALAGCGDGAPAVSSSTTEVTVHGTVTYKGKPVKKGMIRFDPANIARRDAKAASASIGEDGTYTIKTLQGENSVGFELPDLAKRDFALASASFVYDAPAGDSAKDFDLGNQ
>NC_019892.1|WP_015247307.1|4946299_4951402_-|protein-kinase
MNDSELEDDPLGGLADEFLERYRRGERPALSEYMRRFPDLAERIEDLFPALVMLEEVRSGAESPPSALEPIREGKPLAQLGEYRIVRRIGRGGMGIVYEAEQESLGRRVALKVLPPESHRNPHQIERFRREARAAAQLHHTNIVPVFGVGQDGETLYYVMQYIEGSPLDAVLDELRQIRSEAKVEAATHSSSKSAAEPQNSDGKRRRSPLPTPPHASTDVARSLWEGRFRSGSGRKEGSEPSLSPLDQGDAVRADANLALLSPNPAVGSSPSALGANSSSASLSDPRMPYAWSVAHIGVQVADALEHADGQGILHRDIKPSNLLLDLSGTVWLTDFGLAKTSGSADLTHTGDLLGTLRYLAPERFQGRTDVRGDIYALGLTLYELLVLRPAFADHGEERLILQITSGDPPRLDVVDPDLPRDLVTIVHKAIAKDPCDRYQTPGALAEDLRRFLEDRPIVARQAGAVERSWRWCRRNPGLAVSAGSTAIALMTAALLALLYANSQARATAKITGLAHQISHSLNESNHRLAVLDLERGQVACERGEIDRGLLLMVESLRAATAVNDSALRHAARANLSAWSRYLPRLTGAFSHGGLVTQVAFSPDGTKFATGCSDGKARFWDVATGQLTDISLAHQAAVRTLLFSPDGKTILTRSQDGAARLWDVATGQPVGPALAQYGFVEAVAFSPDGKFLLTGSEDNTSRLWNLATGRLASPPLPHPKVVRALAFSPDGKTALTGSQEGVARLWEVATGELAGPLLHHQGPIDVVAFSPDGRLVLTAGQDNTARLWEAATGKPIGSPLRHQNWVEAAAFSPDGKTVLTGSQDSTARLWDARSSDPICLPLLHQGPVRTVAFSPDGKTALTGSGDGSARLWDVATGQPAGPLLRHQGPVETLAFSPDGKAVLTGSHDRTARLWDTTVKEPVGLPLQHQEPVGVVAFSPDGLTALTGSGDGTAQRWDVATGQPAGPSFHHGSPVTSLAYSPDGSIILTGTKDGTAQLWDAASAKPSRPPFQHLGPVRALAFSPDGKLALTGSHDRTGRLWEVASGQPVGAPLYHQGPVVAVAFSPDGKTVLTGSEDNSARIWEVATGRPVGPPLLHHRWVTAVAFSPDGKTVLTGSDDTTARLWNAGTGQPVGPPLRHQTWIRAVAFSPDGKTVLTGSDDTTARLWKTATGEPAGPPLRHEGLVRSLAFSRDGRRIVTGSWDGTARLWDAATGRPIGPPLRHQKWVEAVAFSPDGETILTGSHNQTGRLWRVAEWPDDFPSIEASIEVMTGLETRREGIVHLLDDDTWRLARKRLEPAGDPSVSDPDRGHDPILFGPDPLAPARVWIDRKRWDDAETAFAAAIKARPLNGTIRMERARFFAGQLRMNEADADFAQAYLLGSRNPDLVAEVCNRDHAFQYLMALQPELALELWRKRGEHLVKQKRWAKADAILTEALTSYPEDPWLRISRGRALLGLGRGEQADADFSRATPPSSASPSDYRSLAGEFARQALWEKTALACAKLIELNPSDHDAFYYSTPLYLKLGDLPGYRRHCARLLERYGATTDTTIAERTAKACLLAPLPEPEHALACRLAERSVAAAEANGFALLPYCRLSHALALYRSGRFDDALAESEKCLAQSAGSWNRDIPINLVRAMSLAQLRQDRLAQAAMEATAEIIKKKLPKPELETGWHDWLICTLLQREAEQLILDAPFPGDPIAR
>NC_019892.1|WP_015247308.1|4951618_4952905_-|right-handed-parallel-beta-helix-repeat-containing-protein
MTNVRDFGAVGDGRADETKALRHAVEQGGGQLDFPRGTYRLTAPLEIDLDRSGPIALCGQGGTARLVMDGPGPAVRLVGNHGKSADPTSFEPRVWQHQRMPTVSGLEIVGNHDQADGIEIEGTMQPTLQGILIRRCRYGVRLVKRNRNVLLADLHIYDGRGPAIGVYFDGVNIHQAIITGCHISYCKHAGIKIARSEIRNLQITGCDIEYNFDPGNPDSADVWIDAREATVREGTIASNTIQAKGSPRGANIRIEGAERDDSGGAGLWNITGNVLQDQQVNVWLRYCRGITLTGNTFASAYERSIVLEQCRDIVIGSNVIDHNPDYKGPTIDGIKVVKSAGINLQNLILDGSQAGGPDEGGAIEVVDSSEILILGCQVLDPEFRGVDLRNCRNAKVSACNIVDRRARPTMREPVRIVDGNGKVVAASD
>NC_019892.1|WP_015247309.1|4953117_4954500_+|hypothetical-protein
MKRPWLVQAGYPCRLRSARAWACGFAMVVGLTQGAALVRGADAPPRPRPPATVAEAEKTLDLATFPLLDQAKQVTSRRLAGLSYNVEGSVRRVFEAQRKELTDRNWTERPNSYVSDQSASGLFTKDGFSLSLMVYPPGKPGLVNIALTNHGNVALGKLPVPPGVKPFFGGPVSTSYLTESPVAETAQACRKLLLESGWEPYGDAGDTHFFKQNAVRLAARVTSAPAQGGKTVIDYSTLLMSVDLPAPLETIGLQYADVTKQLLFDTKATEKDVVDFYRKTLAKSAWEATTEAPFKSGFKNMMIFRNPQKDLLTLVMDEIKGQDVNRIVLKHQSAAEVEEIEQRLKAEAEQLEIEKRKPLPKLILAIPGDAKAVMQSKTTIRFEVPDTRARQIAETWRTQFEKEGWEIQASRLEDKGGSIFIAKGRLHTVSLSYTDLRQLPAEVTIRGNGVELVRSAEAKK
>NC_019892.1|WP_015247310.1|4954600_4957387_-|bifunctional-acetate--CoA-ligase-family-protein/GNAT-family-N-acetyltransferase
MSADESKGPGLVPNLVVLQSRRQPLDAIFAPRTIAVVGATEQAESVGKTMLENLLGNPFGRTIFPVNPHRAEVLGVKAYARLADVPEPIDLAIVATPAAVVPEVIGDCASAGVRGAIVVSAGFKEVGAEGAELERRVLEQARRGRVRLIGPNCLGVMRPFNGLNATFARRMALPGGVGFLSQSGALCDAILDWSLRENVGFSAFVSVGSMIDVGWGDLIDYLGDDPHTQCIVIYMESIGDARAFLSAAREVALTKPIIVLKAGRSEEAARAAASHTGAVTGNNDVLDAAFRRCGVLRVDTLAEMFAVAEILSKQPRPRGPRLAIVTNAGGPGVLATDALLKAGGELAHFSNETMATLDACLPPPWSRGNPIDVLGDASAERYTQAVEAAVQDRATDGLLVILTPQALSEPTRTAESLKAFARVEGKPVLASWMGGADVAAGVEILNRAGIPTFVYPDTAARVFHAMWRSTYNLRALYETPTSTDDSHDTALARAAAEAVGAAVRGEGRTILTELESKRLLDAYAIPTVETRFAHDEAEAVEVANALGYPVALKLASETITHKSAGGGVRLDLPDADAVRHAFAEIATAVRERAGAGLGAFQGVTVQPMIRRNGFELIVGSSLDPQFGPVLLFGSGGRHVEVLHDWSLALPPLNTTLARRMMEPTRAYAALKASQGRDLIDSAQLEQLLVRFSRLVVEQPWIKEIDINPLLASREGFLALDARVIAHGPEVREGQWPRLAIRPYPTQYAVPWTAPDGTALLIRPIRPEDEPSFIQFHERLSEQSVSFRYFHAMKLGRRVAHDRLTRICFNDYDREMALVADYQDPATGAREILGVSRLMKQHGRNEAEFALLVVDRFQGRGLGTELLRRLVQVGRDEGLDQINADILPQNRPMLLLCKRLGFSLVQKPGDDVVRAILDLRGSVKAPARP

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Crispr_ID: NC_019892_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_10

4988018-4988120

Orphan

Consensus_repeat	Method
ATTGCAGCCCCGAAGGGGCGACCGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_10

>merge|NC_019892|10|4988018-4988120|CRISPRCasFinder
ATTGCAGCCCCGAAGGGGCGACCGTTTCTAGCCAGGGGTGAAACCCCTGGAAACAGGATGAACTCAAATCAATATGAATTGCAGCCCCGAAGGGGCGACCGTT

>NC_019892|10|9|4988018-4988120|CRISPRCasFinder
ATTGCAGCCCCGAAGGGGCGACCGTT	TCTAGCCAGGGGTGAAACCCCTGGAAACAGGATGAACTCAAATCAATATGA
ATTGCAGCCCCGAAGGGGCGACCGTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015247337.1\|5003882_5004800_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NC_019892.1\|WP_015244773.1\|4985504_4986929_+\|IS1380-family-transposase	unknown	unknown	gnl\|CDD\|379340
NC_019892.1\|WP_015247333.1\|4994846_4996919_-\|DUF4175-family-protein	unknown	unknown	gnl\|CDD\|173412
NC_019892.1\|WP_015247321.1\|4973477_4975091_+\|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl\|CDD\|349910
NC_019892.1\|WP_015247319.1\|4970825_4971920_-\|TIGR03032-family-protein	unknown	unknown	gnl\|CDD\|379811
NC_019892.1\|WP_015247325.1\|4979685_4981269_+\|DUF1549-domain-containing-protein	unknown	unknown	gnl\|CDD\|377872
NC_019892.1\|WP_015247323.1\|4978347_4978692_+\|RNA-binding-protein	unknown	unknown	gnl\|CDD\|240845
NC_019892.1\|WP_015247327.1\|4982751_4984527_+\|EF-hand-domain-containing-protein	unknown	unknown	gnl\|CDD\|183426
NC_019892.1\|WP_015247332.1\|4994207_4994726_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|341181
NC_019892.1\|WP_015247329.1\|4988945_4990667_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369873
NC_019892.1\|WP_015247324.1\|4978859_4979459_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247328.1\|4988439_4988682_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_157579440.1\|4990663_4993624_-\|NPCBM/NEW2-domain-containing-protein	unknown	unknown	gnl\|CDD\|377970
NC_019892.1\|WP_015247320.1\|4972006_4973104_-\|AIM24-family-protein	unknown	unknown	gnl\|CDD\|376704
NC_019892.1\|WP_015247322.1\|4975152_4977882_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|381118
NC_019892.1\|WP_015247338.1\|5004768_5005815_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NC_019892.1\|WP_015247334.1\|4996905_4999143_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247336.1\|5001714_5003877_-\|BatA-domain-containing-protein	unknown	unknown	gnl\|CDD\|131281
NC_019892.1\|WP_015247335.1\|4999201_5001655_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|214621
NC_019892.1\|WP_015247326.1\|4981387_4982755_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247337.1\|5003882_5004800_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.79398e-28
NC_019892.1\|WP_015244773.1\|4985504_4986929_+\|IS1380-family-transposase	gnl\|CDD\|379340	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	0
NC_019892.1\|WP_015247333.1\|4994846_4996919_-\|DUF4175-family-protein	gnl\|CDD\|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	2.71578e-09
NC_019892.1\|WP_015247321.1\|4973477_4975091_+\|M20/M25/M40-family-metallo-hydrolase	gnl\|CDD\|349910	cd05660, M28_like_PA, M28 Zn-peptidase containing a protease-associated (PA) domain insert. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. This subfamily is composed of uncharacterized proteins containing a protease-associated (PA) domain insert which may participate in substrate binding and/or promote conformational changes, influencing the stability and accessibility of the site to substrate.	5.26489e-91
NC_019892.1\|WP_015247319.1\|4970825_4971920_-\|TIGR03032-family-protein	gnl\|CDD\|379811	pfam16261, DUF4915, Domain of unknown function (DUF4915). This family consists of uncharacterized proteins around 370 residues in length and is mainly found in various species, such as Shewanella, Rheinheimera, Saccharophagus, Leptolyngbya and so on. It contains serveral TPR repeat-containing proteins. The function of this family is unknown.	0
NC_019892.1\|WP_015247325.1\|4979685_4981269_+\|DUF1549-domain-containing-protein	gnl\|CDD\|377872	pfam07583, PSCyt2, Protein of unknown function (DUF1549). A family of paralogues in the planctomyces.	1.4343e-55
NC_019892.1\|WP_015247323.1\|4978347_4978692_+\|RNA-binding-protein	gnl\|CDD\|240845	cd12399, RRM_HP0827_like, RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins. This subfamily corresponds to the RRM of H. pylori HP0827, a putative ssDNA-binding protein 12rnp2 precursor, containing one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain). The ssDNA binding may be important in activation of HP0827. .	1.8668e-36
NC_019892.1\|WP_015247327.1\|4982751_4984527_+\|EF-hand-domain-containing-protein	gnl\|CDD\|183426	PRK12309, PRK12309, transaldolase.	1.79622e-06
NC_019892.1\|WP_015247332.1\|4994207_4994726_-\|hypothetical-protein	gnl\|CDD\|341181	cd17292, RMtype1_S_LlaA17I_TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to the S subunit TRD2-CR2 regions of Lactococcus lactis subsp. cremoris A17 (S.LlaA17I), Haemophilus influenzae Rd (S.HindORF215P) and Clostridium species ASF502 (S.Csp502ORF478P). Lactococcus lactis subsp. cremoris A17 S subunit (S.LlaA17I) recognizes 5'... CAANNNNNNNNTAYG... 3', while the recognition sequences of Clostridium species ASF502 S subunit (S.Csp502ORF478P) and Haemophilus influenzae Rd S subunit (S.HindORF215P) are undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It also includes TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases, such as Porphyromonas species COT-108 OH1349 Type IIG restriction enzyme/N6-adenine DNA methyltransferase (RM.Psp1349ORF730P) of unknown recognition sequence. It may also include type I DNA methyltransferases.	0.00810311
NC_019892.1\|WP_015247329.1\|4988945_4990667_-\|hypothetical-protein	gnl\|CDD\|369873	pfam08432, Vfa1, AAA-ATPase Vps4-associated protein 1. Vps Four-Associated 1, Vfa1, in yeast, is an endosomal protein that interacts with the AAA-ATPase Vps4. It would seem to be involved in regulating the trafficking of other proteins to the endocytic vacuole. There is a CCCH zinc finger at the N-terminus.	0.00577386
NC_019892.1\|WP_015247335.1\|4999201_5001655_-\|VWA-domain-containing-protein	gnl\|CDD\|214621	smart00327, VWA, von Willebrand factor (vWF) type A domain. VWA domains in extracellular eukaryotic proteins mediate adhesion via metal ion-dependent adhesion sites (MIDAS). Intracellular VWA domains and homologues in prokaryotes have recently been identified. The proposed VWA domains in integrin beta subunits have recently been substantiated using sequence-based methods.	2.56303e-06
NC_019892.1\|WP_157579440.1\|4990663_4993624_-\|NPCBM/NEW2-domain-containing-protein	gnl\|CDD\|377970	pfam08305, NPCBM, NPCBM/NEW2 domain. This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins. This domain has also been called the NEW2 domain (Naumoff DG. Phylogenetic analysis of alpha-galactosidases of the GH27 family. Molecular Biology (Engl Transl). (2004)38:388-399.).	1.50753e-45
NC_019892.1\|WP_015247320.1\|4972006_4973104_-\|AIM24-family-protein	gnl\|CDD\|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	8.28349e-44
NC_019892.1\|WP_015247322.1\|4975152_4977882_-\|PAS-domain-S-box-protein	gnl\|CDD\|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.39066e-52
NC_019892.1\|WP_015247336.1\|5001714_5003877_-\|BatA-domain-containing-protein	gnl\|CDD\|131281	TIGR02226, hypothetical_protein-transmembrane_prediction, N-terminal double-transmembrane domain. This model represents a prokaryotic N-terminal region of about 80 amino acids. The predicted membrane topology by TMHMM puts the N-terminus outside and spans the membrane twice, with a cytosolic region of about 25 amino acids between the two transmembrane regions. Member proteins tend to be between 600 and 1000 amino acids in length. [Hypothetical proteins, Domain].	3.80226e-19
NC_019892.1\|WP_015247338.1\|5004768_5005815_-\|AAA-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	5.28585e-94
NC_019892.1\|WP_015247326.1\|4981387_4982755_+\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	1.10452e-110

>NC_019892.1|WP_015244773.1|4985504_4986929_+|IS1380-family-transposase
MATECNSTYLDFSILGHRQVLADFDGGAISSDGGALLLRQIEARTGIIRQFAACFTDHRDPDLVEHPLEHLLAQRVYGLALGYEDLNDHDDLRCDPLLATVVGKTDPTGQDRPRLRDRGKPLAGKSTLNRLELTPVGADGQSRYKKITCQTHEVERLFVTLFLQAHSRPPERIVLDLDATDDTVHGRQLGRFFHGYYKGYCYLPLYIFCGDHLLCARLRPSDIDASAGSVKSLKRIVSQIRQAWPQVKILIRADSGFCREEILRWCEDNGVDYLIGLAKNTRLTAAIATELAQARQQFEATKQPSRVFAELRYQTQKTWSRERRVVAKAEHLGKGANPRFVVTSLTVEERAAPPLYEQDYCGRGEMENRIKEQQLHLFADRTSAHTMRANQIRLFFSSIAYVLLEALRRLGLAGTAMAEAQCQTIRLKLLKIGALVRVTVRKVWVKFSSGCPYAEVFRRVHTNLARSGPLIPRC
>NC_019892.1|WP_015247327.1|4982751_4984527_+|EF-hand-domain-containing-protein
MTFATPCVALALALTVTAAAGPPEEAAKTEGEAERNVVFLGEERPVFLRLRVMAGDRPFDAAWLDSIRTIHACLDLDGDGKLTEKEADRGALAALVRLATGGATTLLRGELDVHPKDGVVSIDELAEALRPVIGPFRVQVGRLAINRTDALFDHLDRDKDGALTRTELAAIAGSLRRLDLDDNEMISATELEPFNSPTAMAVAGNAADRQARLIAVPPVVELVAGVSSLRLARLLLKKYDKGRGDVPGRPDGKLSPEEFAIDPDAFASADANHDGALSTEELRKFLAQAPVDLDLEINLSPDASGSGSGPGRATTRIRGDGGLAKGTEVRQLADGDVEIAVGRIRLDIHVDQGDAVAENARRIYQRLFKAADANKDGYLEGKELPAENNDAPVQVQVQGQVSPLAGLVKVIDRDGDGKLYEKELMEFADRQSEAARGRLVLTASDQGRAIFGILDLDRDRRLSAREVMRTVDRITSWDGDSDGRVTADEIPYHFQVNIARGELTGLIGGGGAGNNVVAPQAMMAAPKPAALTAGPDWFRQMDRNHDGDISRREFLGPRTEFDRLDRDKDGLIDAEEAEAGAGAASRGNAGP
>NC_019892.1|WP_015247326.1|4981387_4982755_+|DUF1501-domain-containing-protein
MNRPRPTYQVPPLTRRQVLRLAALGALGASSSGWIETLAANTAADPNRRKSCILLWMTGGPSQTDTFDPKPGHANSGPFKPIETTVPGMLLGPHLPQLARQAKDLALVRSMSSKEGDHGRATYYLRTGYLPQGPVRHPTLGSLVANEFEDKSAELPGFVSISPFRAFNPAAFGAGFLGPKCAPLIVGERPVGGGGGGDASTQPSLRVEDLDAPHDINRARADDRLQLMHTLGSDFLASRPGLAALSHQDAYQRAVKMMRSSAAKAFELDEEPAALQDAYGRNPFGQGCLLARRLVERGVPFVEVTLSSVDGSMAFGWDTHQQNFDAVEKLSGVLDAGWATLMTDLRSRGLLDSTLIVWMGEFGRTPKINENAGRDHFPNAWSTVLAGGGIRGGQVIGDTGADGEEAKDRPVMVPDLLATVVRSLGIDPMKQNVVDTGRPIRLVDPKANPIKELLG
>NC_019892.1|WP_015247325.1|4979685_4981269_+|DUF1549-domain-containing-protein
MLIRRAWVAVACLVTLGATAKGADVAGGQKEPAPSARDARSLAARIDAVLAARWADAKIKPAAVADDGEFLRRVSLDLVGKIPTAAEARDFLDDPSLDKRQALVERLLDSPAYTTRATELWRQLLLPEADTEDQARVVAGSFEAWLRRKVVEEAGYDRIVREILTTKLNDRNTEAMASRLDPSPAAYYVAKEGKPENLAAGAARVFLGVRLECAQCHNHPFAAWKRDDFWGFAAFFAGVPSPNSDGTAAVRMPRDAPPLRELTIPGTKKIVKAAHLDGSKPDWRPRAETREILAEWITAPQNPYFAKALVNRVWARFFGVGLIEPVDDLDLESDPEFGGLVNELAVQFRLHDYNLKYLIRVLTATQAYNLSSIAAPSESSSPMFAYMPVRGLSPGQLFDSLSQATGADAAGARGRFLDLFANRDERATEAQTTILQALTMMNGSHIAGATNPATGEVLGAVTKAPFLDTPGRIETLYLATLTRRPKPEELALLTRYVDRTESPEERAKALADVFWAILNGPEFHLNH
>NC_019892.1|WP_015247324.1|4978859_4979459_-|hypothetical-protein
MGIFGPSKDEVWRQLSHEIGAEFVEGRFWSGNRVQAYIAPWTITLDTHTVSTGHSHITYTRMRAPYVNPDGLRFTLYRKGLFSELGKLLGMQDIEVGDPDFDEAFIVKGTDEFKVRELFDDPQVRALALAQPTIHLSVKDDEGWFGAKFPKGVDELHFQVVGILKDGPQLKALFDLFAAILDRLCEMGAGRKEEPGVRL
>NC_019892.1|WP_015247323.1|4978347_4978692_+|RNA-binding-protein
MGKKLYVGNLTYNVNESDLEALFTPFGTVQSAQIIIDRDTNRSKGFGFVEMDTDAQAQAAIQGLNDRDHDGRNLTVNEAKPREPRSGGGGGGYGGGGRSGGGGGGYGGGGGGRY
>NC_019892.1|WP_015247322.1|4975152_4977882_-|PAS-domain-S-box-protein
MLSPARTPLLRYGGAVLAVLLATTVRWVLDPFIGAQFPLSTFFAALVFAAWYGGFGPALVAMSLCSPVITYFILPPYGSFFLDSYEGQVRFGAFLIAGLVIAVMGGTIRAARHRAETAAKEDRVKQRLLEQEVVERRGVEAALRVEKERLRVTLASIGDAVIVTDADGRVNFLNPIAEALTGWSTGEAAGQPLEAVFRIMNQETGKPIASPTLQALRGETTGGLADHAVLVARDGRERPIDDSAAPIRDESGRIVGVVLVFRDVTERRRADEIRRHLAAIVESSDDAILGTTLDGTITSGNSGAERLYGYTAEELVGQSAALLIPAERFDEFRATLNQIHQGMNTDHFESKRRHKDGTLIDVSVKVSPIRDGFDNVIGASTVARDITARKRAEKRLAESEQRFSRFMQHLPGLAWIKDLEGRYLYANEAALKAFQISRADLYGKVDDEVFPPETAALFRENDRKALAVEMGIQVVETLLQDDAIVHHSLVNKFLILGQDGNDTLIGGIATDITERMRMVESLREADLRKDEFLATLAHELRNPLAPIRNALHLMKPANRDCDDLERERAMAERQVTHLARLVDDLMDISRINRGKIELRKEVVELATIVGRATEAVKSSLEERGHSLCLSLSDRSIHLEADPTRLEQILGNLLNNAIKYTQPGGQISLIIEREHENVLIRVRDTGIGIEPEMLPRVFGMFVQAGHHTGHSHGGLGIGLSLVKTLVELHGGTIEATSRGPGAGSEFVVHLPILPGIPAASAIHRVPEDPPRPDAAVADTEQPTRRRILVVDDNLDAANSLARLLRRLHGQEVEVAHDGPAALEAAEAFRPELVLLDIGLPGMDGYEVARTLRDRPESATIRIIALTGWGQESDRQRSKEAGFDHHLVKPVDPDLLSTILRDYEMTPTAKA
>NC_019892.1|WP_015247321.1|4973477_4975091_+|M20/M25/M40-family-metallo-hydrolase
MKLWQPIDLVRAALVVVIVVVAVTASAEAADKPDGTRWWSHIRFLADDALEGRNTGTEGHRKAAAYVAEEFAKAGLKPAGLDGYFQPVQLISSEIDESRSSLSLVRAAGTEPLTLGEDANIGLRVDPAPALDAELVFAGYGLSIPEAGYDDFQGLDVRGKVVVYLAGPPPSIPGPLAAHMQSAHERASVLSRLGAIGTVAIPNPKNMDIPWERSTLARLMPAMRLADPALDESFGLKIGIAVNPAHADKWLAGSGHTFQEILEAADAGKPLPHFPIPTRLEAKAAVKRAPVESQNVAAVLPGSDPRLKEEYVVFSAHLDHLGIGKPIDGDAIYNGAMDNAAGIATMLEIATSLKESGTALRRSVLFVAVTGEEKGLLGSRYFATHPTVDARKIIADINVDMFLPLFPLKLLTVYGLNESDLGEDATAVAESVGVASQADPEPKRNLFIRSDQYSFIRVGVPSLALKLGFGKGSPEERIAKEWLTKRYHAPSDDLNQPVDKQAAAEFNALVAKLLERVANRDERPRWKDDSFFKRFAK
>NC_019892.1|WP_015247320.1|4972006_4973104_-|AIM24-family-protein
MAAEWYFRVMGTEFGPVSTQELVQQAGDGKIGPDTEVRKGNGAWVPASRIAGLFDRGVRNKVALPTAVAPPPLPREEVNVFVPAQKPPLAPALAWDKFEVIDSAEDDQFRVEVLAYSSLGGAKDHQTAATVYFANQAGIRLKQVRITMRDGEAIAESGALHFMLGQIQMESKIGGVSGLGKAMMNRFITKEAAVMPRYRGTGQIYLEPSFSHFLIYRLNGEEVIADKGMFYCGQGTLDVGSAVQKNVSSALFGGEGFFQTRIRGAGICVLESPVPVDEVMRIDLKDETLQVDGNFALMRTGRIEFSVEKSTRSLLGTLTSGEGLLQTFRGTGSVWLAPTQDIYQRLQTGGIASMSAASRTSHTAT
>NC_019892.1|WP_015247319.1|4970825_4971920_-|TIGR03032-family-protein
MNPNSPSSAVMEPVSVLGSPGLTGWLRDQRLSLAFTTYQSGKLLLVGRKPENSLAVFERTFNRAMGLWSDGQTIWLSSAYQLWRFENGLSPGQIDEGFDRLYVPRAGYTTGDLDIHDVARNVTGQVVFVNTRFSCLATLSEQHSFTSLWKPWFIDRLAPEDRCHLNGLAMVDGQPRYVTASACTNHAEGWRDRQREGGVVIDVLRERILVEGLSMPHSPRWYRDRLWLLDSGNGTFGWVNPSRPEFTPITVCPGYARGLAFVDHYAVIGLSRPRQGGVFGGLNLDARLIREGIAPRCGLIVVDLDSGAIVHSLDIQGPIDELYDVVVLPEVVRPMALGFKNDEIRYTVTTEGLSGTLWKVNSGR
>NC_019892.1|WP_015247328.1|4988439_4988682_-|hypothetical-protein
MIDTTTRRPLRVSTDGTAGPYIMVPVSQLDRVRRLLLDNKIPHRVDEDAISLGGNPAVVVIDLVRSDDAERTQAILDANA
>NC_019892.1|WP_015247329.1|4988945_4990667_-|hypothetical-protein
MSRPIIMRQSLGRSFSFRLAPLLALSLIGAWLPAALAEDDKPQPAIEVYDWSIWVTSPAQLTLNGTRVYKNAMPGVVGTSRPKLEGKELVGKFPIAPISVVQFFGEPSRDLDIDLRVKKGTLVAHWPPGSERAGRIQWFKSDLTKALAAGVPLGFLPEAHWLPQLRKVESALYHQRESRAERFLAYDTELAIPIPLKLRGGPDEYTLQNLTGLKLLDVAVIAPTDGGYRVGWLDELPSATPEGKDEGSVKKAKEKEEQERKKKPASEKANEVFEKAETDAKKEKDKDKEKDEPKPLPAEGDADVRARVDQILNRPINVNVEQAPRKEVLDLVTGQARVRYELDDKTLIKEEVDLGKTMSLKAPNIAARDALAEVLGTIGLSYRVTEDGSLFITTAARLAEDSGKKGAVIEGPPVKLTLSKPLKASDPSYRELTRDSYTRRLAAQGLRDEVIESLLGQYSEALFAPDGLIVLAHFSRDAIDDAVLLDVFPSPKKFVRTAALVMHGIDPRLQDKARELVQKLGDPAPKARETAETQLFDLGPVAVPVLEDALRDKDVEIVFRAERLLLKLNRQVP
>NC_019892.1|WP_157579440.1|4990663_4993624_-|NPCBM/NEW2-domain-containing-protein
MAQLAAFIDRGHAMHRVVLLWVSLLTGDVHEYSRPLDAKKIEQATLDAESYGEKKQVKREDDGLHITLAPGEAETGWKTPQTLKFGGNFTITANFVVRKLPKPAQDDGTAVGLAIATQNVDQPDATLVRLVETTGANVYRSIGKAGNAQGPQGMQMQMQMQMMAMQGMGMPQPGGKPPKLPRQTFPAKGEAFRLELKREGSTVRYHVLDGESGSGRYLGQIELGAGDIAGVKLFAVNRNGAEGLDIVLRDLTVRADRINGLGTEVRTVFGEIFHGEPTALEGGKLIVGGPPPVAPPATPPTTPGPKAAATPGEAKPAGAASPPATEAAKPDQAKAEKETGGSPVKENATEKAKDTDAKDKPKEDTKDKPKEDTKDKPKEDTKDKPKEDTKDKPKEDAKDKPKEDTKDKPKEDAKDKPKDANAKEAPKPTPPPKVEPKARVPLDEVEGIAFEKALTLSGRVLGQPNLDFTRPGLEAPKDGAVAKSDTKTDDVLAPPPGTVTPAKIPKVEPKPNGICDLHLTLANLRTAAIKQVTINAQTDKGPAAWRLDTSDSRDWPLVVRRAGTETWADLFLEPPAGDLNGKDLTVNITYADGQNANATIKSDKRSDPKLAVDPTAPAPSLDARVYLTGDEQLFGKFEGLGEDSLRLQTPWGDRLTVPLARVIGIYMGLPEHKESAESFAKRLRTRGTEDLLLARSKDDEIVAIPGIAEGTKEDKLLFHFQEKTRSLPLKQVEGLVLAARPEPERPDGLRPTFSMAGGIVVSGLWKTLEAKTWKIETAWGQSLDLPAAEVRSVRFQGGQMTYLSDLEPSRVDETPFFTRRSPWRKDVNLAGAPLKVDGITYEHGLAVHSRSALTYDLNGEYTTFEAVVGFDDDAKKLGRVDCRVFADGKEIYANPDLRADAPPVKLSLPVAKAKQLKLLIDFGPDQDTGDRVIWANARLFRKPPPTKTEVAAKTAPADAAKPGSPEPQNTKTPTPTNTTTKPGSGK
>NC_019892.1|WP_015247332.1|4994207_4994726_-|hypothetical-protein
MRQNIRILGASALMSCLLQPAFAADPPAAAIALKMANVTDELNRTETGKPVQTEQKAIVQDLDELIASLEKQCQACKSGMKRNNPNKGMADSTISSGSGGIGTLLNPSDTGKDWGKLSGRERDRILQSMSEGFPPEYRTVLERYYRRLAEEKSSSSAQAKASSAPTKADETP
>NC_019892.1|WP_015247333.1|4994846_4996919_-|DUF4175-family-protein
MKSPSTHRRPGITAGRLALFLWIATATHVMPRLAQAQAKPDAAKAASVFDDEKADEKKPDDKKADDKKADDKKADDKKPNDKKADDKKADDEKKKADDEKKADEKQKADDEKMAKEKEQAKKATASERDSIGFTQENVAAQMTELEERMFRLSEALRGLEPENASRLRLALKFSREEQILDQMRETHKFMKDAQLSKAETEVRELVAKLEHLRNLLLAEDLDFQLKVARLRQMREALSQLDRIVKEEKRELGWSRFAIEQRKGLDRLAARRPDLEALARDQKALVADTKNAPPNGDAVKEAKAAIREREVKIRNTANALATDPLFADLQPPHLRRADAHLGDAVSLLEGTDVDAAVEAEEKALAMIGQELTRFDEQVAQSKQTIADGEFKRRQGDQSKNRAATDTLSEVSARLGDTGVALRKDLIRASGSMRTAEEGLGQTAAEPAADNQSAALEALTKSREELAQAVEKLLVELRKELQARLVAELTEMHELQAAIRETTQAQAPRVLQKSRTALIAVSGLSKKEAELGERTEHLLALVEETEFGIALPTTLRVLGREMRNIEGWLKAGDVAPRTIALEIRVEEDLLGLLQAIRRLPPGTPPPPGSPLPSDLRERERELNRLVAELKMIRMLQSRLNDDTVGVDKSRPDISELPPALRREVEALEASQDEIRESLAKIAERLENPDDNP
>NC_019892.1|WP_015247334.1|4996905_4999143_-|hypothetical-protein
MTTATDNTSLGSLREEQALLRSRLARLRRRLQLQMALEFALDAAVALVATAALLVFLDWWFRLNLPARLILLAAVLIGVVPFAILRALRGWRAARLDDLSLAVTLDRFRPGTGGRVADVLQLPDQLGESEESVSPAMIRLAVRQASEALAASDWASLWNRGRTLKRSAALLAALLVPTAFALIAPQAARLSAARWLQGSTERWPQRTYLSVVGLGDRNRILAPRDETFALEVRADLASVEPRKGHWIVSGRGEPLILRSLPKTPEVPKAVRVRERAAKGAVRDAVMVATGPSLFRYELPPSSTSTTFDLTGGDDWLGPVKVDRVDRPSLAATKLRVKEPGSPGNEFRAIDASAQHPVFLPDTEVELTLVGSEPIADAQLTVHPGQPPKLNRVDASTFTARWTLREAITLEIQLTSKATGLTSKPAFFSIGLLKDREPRVALRALGVGAHVTPVATIPLSLNATDDLGLSAVRLQLERTTAAGEKEKDKGEPKTTKKTVLLPLTTDGARAVLDHQARHDVELQADPPPLGTILRFVAEAEDKCARGVQVGRSAALQFQVVAPDELFYEILIRQRAERAKFVMLYEAAEKRATALSGAPSADDYATAMRGLNNGSRQLDLIAGRIADTLQEMKLNQVGSPKSHRLLQEGVIDPIRALNAGTVNELRSVLQSLTGTAPKAGADAESVRRLHGEVVAGMKIILDQMSQWESFVDVVNQVAEVIKMQQNVLQAAEKARESRTQEVFDEKP
>NC_019892.1|WP_015247335.1|4999201_5001655_-|VWA-domain-containing-protein
MSSIWKWLLGIDRSPGEVAPGGSTRLELSALPEGSAALAVLIAAVALTALLWKLYRRERRDLSQSRRTLLVGLRLLVLVAVAVMLIEPVLITVRRETVPSHLPIIIDDSESMKFADPYTDETKAAEVAAALELRSEGGKSPVDRLRETPRLDLIKASLRPNLAKLGRGREVFLSDLEAGVRSGTASSPSRNKKLDDLKPNRGVSPLGDALRDVLASHRGRPVAGIVLVTDGRSNAGEDPLKAVEAAIRQGIPVFPIAAGAEEGPRNVRLAEVEASPVVFARDPMTVGVMIEARGLKDAEGTVTLEQRINDNDWETIGDQRVALGEDGVLKRTTFRITPKVVGQYEFRARVGDAGPELTLEDNVATTPVRVVRQQIRLLMIAGSPSAEFQFLRNALQRDQHVESGIWLQHADPGYKQGGDRPIQRLPSDAAELGRYDALLLVDPDMRALGAQWPEMIMNFVGKEGGGLIFVPGELYSQQLFETDDAESEGGQWTRLLPVVREPGLFRTEAQVRLSTQTTYLLELTPEGRGDPIFEFNSDPIRNRAILTSLPGMYWSFPVTRARPGATVLARHGDPRMQNQYGRHVLLASQLYGPGRTVFIGFDSTYRWRYLSEDYFDGFWARLVDRVGRNKALGGRFPFQVHLGKSAYRVGDQVTVGVRFTEAAAVAEAAGLAAELEIGDQPAEPIHFERAIDDAELLTATFPAEKAGSYSLKITPATGAEEGSSVRVSTTTFRVEPPRREIDEPSLNRPLLADLARLTKGKVFDLPTISKLDDAIAMREVTRTLEDREELWDAPLLYATIILGLTSEWVLRKVFRMV
>NC_019892.1|WP_015247336.1|5001714_5003877_-|BatA-domain-containing-protein
MFTFLSPLLIWGALLGVIPIIIHLLNRRRFRRVEWAPMRYLKLTIQRNRRRIQIEQLLLLLLRIALPVLLFFFLARPLVNPTGLERWLGGGGRTSHVILVDDSLSMGYVSDGPPAFHRAREVAAALLAATRPGDRCTLVASSAPRTPVFLEVEGTRREELSGDALSIPQTETHAAWPAVLEGVDGVLQSCTYPTRQLTIITDLRKAGWEAGVSAIARRWNEQGLHVRIVDVGADEVANVALESLVPLDRTILAGAESRWEALIRNASPRVITGAKAILRVDDRPIELTLPEIAPRQTAKVPLTVRFPGSGPHDVSLQLPEDELPGDNQQWAAVPVKDSLLIRLVDGEPSSEPFGSEVDYLAAPLSIGVGDAEAWRVETVQEEDFLSPRFEPADVLVLANVAAPTAEQATQLARLVRGGMGLMIFTGAKLDHGLYNDLLYRTGEKLLPLPLKAQVDGEIRGLFIEPVRPSPIEKLLELRPSALERVTARQIMTVGDEADEAKVRVLARWNDVARSPAIIERVVGDGRVLFWTSTADRAGNDWPIEPSFVLAVREAVRGTARPTSLANTVTAGDRPRRVVRSSQQVVNAKVSPPGTGEPQALAAVPLADKAADDLGPAVAIDLPDTRRAGLYRLTWDEGPLGTQQDLFAANPDRRESALARIKERDLKALLQPLKLEVASARGDGIDAFSATGQEVWHQLAWGLLALLILEPILATWVGRSR
>NC_019892.1|WP_015247337.1|5003882_5004800_-|DUF58-domain-containing-protein
MPPSRTYSDPDTIAQIADLTLRSRRLAEGGISGQHRSPFHGFNIEFASYREYTPGDDLRRLDWRVFARSDRHYIKQYEEESNARVTFVVDASASMNYRGSKAALSKFDYGATLVVTLAMLLARQQDPVGLVLFDEDAGTVLAPSATQSQVTVMSGLLEGCVPARKTELGGMLRSLAGRIRRRGLLVIVSDLFTDLEAVYDSLNRLRFQGHEVLVLQVLDRDEIELPFDGPTLFRDIEGDEELYAEPGAFRLAYRRAMDEFLDGVSKECGARGYDHVRFFTDTPLSVSLSSFLHARQEAGGTGGRG
>NC_019892.1|WP_015247338.1|5004768_5005815_-|AAA-family-ATPase
MSTATEDLDLAELDELRTAHQQIRQQIARQIVGQDDVVDQLLIAVFARGHCILEGVPGLAKTLMVNSLARSLSLEFNRIQFTPDLMPSDITGTEVLYEDRTTGARELRFVHGPIFANLILADEINRTPPKTQAALLEAMQERQVTVGGHRHPLPDPFFVLATQNPIEQEGTYPLPEAQLDRFLFKIFINYPTPEEERRIYRITTGVEQPEITPLISGERIASLQRLVRRVPVSDQCIDYSMDLVRATRGPAHGGPKYIGDWVSWGAGPRAGQALILASKARAALAGRPSVSIDDIQTVARPVLRHRIVINYNAQAAGESSDSIIKRLLEDIPVRKGAADAAVADVFRS

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Crispr_ID: NC_019892_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_11

4993830-4993936

Orphan

Consensus_repeat	Method
TTGACGGTCGCCCCTTCGGGGCTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_11

>merge|NC_019892|11|4993830-4993936|CRISPRCasFinder
TTGACGGTCGCCCCTTCGGGGCTGCGGTAAAACGAAACAGGTTTTGGGCATTTGTCGTTTTCAGGGGTTTCACCCCTGGCTATTAACGGTCGCCCCTTCGGGGCTGC

>NC_019892|11|10|4993830-4993936|CRISPRCasFinder
TTGACGGTCGCCCCTTCGGGGCTGC	GGTAAAACGAAACAGGTTTTGGGCATTTGTCGTTTTCAGGGGTTTCACCCCTGGCTA
TTAACGGTCGCCCCTTCGGGGCTGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015244773.1\|4985504_4986929_+\|IS1380-family-transposase	unknown	unknown	gnl\|CDD\|379340
NC_019892.1\|WP_015247332.1\|4994207_4994726_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|341181
NC_019892.1\|WP_015247341.1\|5007837_5009949_-\|PQQ-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|379140
NC_019892.1\|WP_015247339.1\|5005830_5006970_-\|terpene-cyclase/mutase-family-protein	unknown	unknown	gnl\|CDD\|238362
NC_019892.1\|WP_015247325.1\|4979685_4981269_+\|DUF1549-domain-containing-protein	unknown	unknown	gnl\|CDD\|377872
NC_019892.1\|WP_015247323.1\|4978347_4978692_+\|RNA-binding-protein	unknown	unknown	gnl\|CDD\|240845
NC_019892.1\|WP_015247327.1\|4982751_4984527_+\|EF-hand-domain-containing-protein	unknown	unknown	gnl\|CDD\|183426
NC_019892.1\|WP_015247333.1\|4994846_4996919_-\|DUF4175-family-protein	unknown	unknown	gnl\|CDD\|173412
NC_019892.1\|WP_015247329.1\|4988945_4990667_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369873
NC_019892.1\|WP_015247324.1\|4978859_4979459_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247328.1\|4988439_4988682_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_157579440.1\|4990663_4993624_-\|NPCBM/NEW2-domain-containing-protein	unknown	unknown	gnl\|CDD\|377970
NC_019892.1\|WP_015247336.1\|5001714_5003877_-\|BatA-domain-containing-protein	unknown	unknown	gnl\|CDD\|131281
NC_019892.1\|WP_015247322.1\|4975152_4977882_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|381118
NC_019892.1\|WP_015247340.1\|5006966_5007845_-\|SIMPL-domain-containing-protein	unknown	unknown	gnl\|CDD\|225516
NC_019892.1\|WP_015247338.1\|5004768_5005815_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NC_019892.1\|WP_015247334.1\|4996905_4999143_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247337.1\|5003882_5004800_-\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NC_019892.1\|WP_015247335.1\|4999201_5001655_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|214621
NC_019892.1\|WP_015247326.1\|4981387_4982755_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015244773.1\|4985504_4986929_+\|IS1380-family-transposase	gnl\|CDD\|379340	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	0
NC_019892.1\|WP_015247332.1\|4994207_4994726_-\|hypothetical-protein	gnl\|CDD\|341181	cd17292, RMtype1_S_LlaA17I_TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to the S subunit TRD2-CR2 regions of Lactococcus lactis subsp. cremoris A17 (S.LlaA17I), Haemophilus influenzae Rd (S.HindORF215P) and Clostridium species ASF502 (S.Csp502ORF478P). Lactococcus lactis subsp. cremoris A17 S subunit (S.LlaA17I) recognizes 5'... CAANNNNNNNNTAYG... 3', while the recognition sequences of Clostridium species ASF502 S subunit (S.Csp502ORF478P) and Haemophilus influenzae Rd S subunit (S.HindORF215P) are undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It also includes TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases, such as Porphyromonas species COT-108 OH1349 Type IIG restriction enzyme/N6-adenine DNA methyltransferase (RM.Psp1349ORF730P) of unknown recognition sequence. It may also include type I DNA methyltransferases.	0.00810311
NC_019892.1\|WP_015247339.1\|5005830_5006970_-\|terpene-cyclase/mutase-family-protein	gnl\|CDD\|238362	cd00688, ISOPREN_C2_like, This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate complement. Class II terpene cyclases include squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY), these integral membrane proteins catalyze a cationic cyclization cascade converting linear triterpenes to fused ring compounds. The protein prenyltransferases include protein farnesyltransferase (FTase) and geranylgeranyltransferase types I and II (GGTase-I and GGTase-II) which catalyze the carboxyl-terminal lipidation of Ras, Rab, and several other cellular signal transduction proteins, facilitating membrane associations and specific protein-protein interactions. Alpha (2)-M is a major carrier protein in serum and involved in the immobilization and entrapment of proteases. PZP is a pregnancy associated protein. Alpha (2)-M and PZP are known to bind to and, may modulate, the activity of placental protein-14 in T-cell growth and cytokine production thereby protecting the allogeneic fetus from attack by the maternal immune system.	3.06231e-13
NC_019892.1\|WP_015247325.1\|4979685_4981269_+\|DUF1549-domain-containing-protein	gnl\|CDD\|377872	pfam07583, PSCyt2, Protein of unknown function (DUF1549). A family of paralogues in the planctomyces.	1.4343e-55
NC_019892.1\|WP_015247323.1\|4978347_4978692_+\|RNA-binding-protein	gnl\|CDD\|240845	cd12399, RRM_HP0827_like, RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins. This subfamily corresponds to the RRM of H. pylori HP0827, a putative ssDNA-binding protein 12rnp2 precursor, containing one RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain). The ssDNA binding may be important in activation of HP0827. .	1.8668e-36
NC_019892.1\|WP_015247327.1\|4982751_4984527_+\|EF-hand-domain-containing-protein	gnl\|CDD\|183426	PRK12309, PRK12309, transaldolase.	1.79622e-06
NC_019892.1\|WP_015247333.1\|4994846_4996919_-\|DUF4175-family-protein	gnl\|CDD\|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	2.71578e-09
NC_019892.1\|WP_015247329.1\|4988945_4990667_-\|hypothetical-protein	gnl\|CDD\|369873	pfam08432, Vfa1, AAA-ATPase Vps4-associated protein 1. Vps Four-Associated 1, Vfa1, in yeast, is an endosomal protein that interacts with the AAA-ATPase Vps4. It would seem to be involved in regulating the trafficking of other proteins to the endocytic vacuole. There is a CCCH zinc finger at the N-terminus.	0.00577386
NC_019892.1\|WP_015247335.1\|4999201_5001655_-\|VWA-domain-containing-protein	gnl\|CDD\|214621	smart00327, VWA, von Willebrand factor (vWF) type A domain. VWA domains in extracellular eukaryotic proteins mediate adhesion via metal ion-dependent adhesion sites (MIDAS). Intracellular VWA domains and homologues in prokaryotes have recently been identified. The proposed VWA domains in integrin beta subunits have recently been substantiated using sequence-based methods.	2.56303e-06
NC_019892.1\|WP_157579440.1\|4990663_4993624_-\|NPCBM/NEW2-domain-containing-protein	gnl\|CDD\|377970	pfam08305, NPCBM, NPCBM/NEW2 domain. This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins. This domain has also been called the NEW2 domain (Naumoff DG. Phylogenetic analysis of alpha-galactosidases of the GH27 family. Molecular Biology (Engl Transl). (2004)38:388-399.).	1.50753e-45
NC_019892.1\|WP_015247336.1\|5001714_5003877_-\|BatA-domain-containing-protein	gnl\|CDD\|131281	TIGR02226, hypothetical_protein-transmembrane_prediction, N-terminal double-transmembrane domain. This model represents a prokaryotic N-terminal region of about 80 amino acids. The predicted membrane topology by TMHMM puts the N-terminus outside and spans the membrane twice, with a cytosolic region of about 25 amino acids between the two transmembrane regions. Member proteins tend to be between 600 and 1000 amino acids in length. [Hypothetical proteins, Domain].	3.80226e-19
NC_019892.1\|WP_015247322.1\|4975152_4977882_-\|PAS-domain-S-box-protein	gnl\|CDD\|381118	cd17580, REC_2_DhkD-like, second phosphoacceptor receiver (REC) domain of Dictyostelium discoideum hybrid signal transduction histidine kinase D and similar domains. Dictyostelium discoideum hybrid signal transduction histidine kinase D (DhkD) is a large protein that contains two histidine kinase (HK) and two REC domains on the intracellular side of a single pass transmembrane domain, and extracellular PAS and PAC domains that likely are involved in ligand binding. This model represents the second REC domain and similar domains. DhkD activates the cAMP phosphodiesterase RegA to ensure proper prestalk and prespore patterning, tip formation, and the vertical elongation of the mound into a finger, in Dictyostelium discoideum. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	4.39066e-52
NC_019892.1\|WP_015247340.1\|5006966_5007845_-\|SIMPL-domain-containing-protein	gnl\|CDD\|225516	COG2968, COG2968, Uncharacterized conserved protein [Function unknown].	3.66995e-12
NC_019892.1\|WP_015247341.1\|5007837_5009949_-\|PQQ-like-beta-propeller-repeat-protein	gnl\|CDD\|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	2.15744e-13
NC_019892.1\|WP_015247337.1\|5003882_5004800_-\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	1.79398e-28
NC_019892.1\|WP_015247338.1\|5004768_5005815_-\|AAA-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	5.28585e-94
NC_019892.1\|WP_015247326.1\|4981387_4982755_+\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	1.10452e-110

>NC_019892.1|WP_157579440.1|4990663_4993624_-|NPCBM/NEW2-domain-containing-protein
MAQLAAFIDRGHAMHRVVLLWVSLLTGDVHEYSRPLDAKKIEQATLDAESYGEKKQVKREDDGLHITLAPGEAETGWKTPQTLKFGGNFTITANFVVRKLPKPAQDDGTAVGLAIATQNVDQPDATLVRLVETTGANVYRSIGKAGNAQGPQGMQMQMQMQMMAMQGMGMPQPGGKPPKLPRQTFPAKGEAFRLELKREGSTVRYHVLDGESGSGRYLGQIELGAGDIAGVKLFAVNRNGAEGLDIVLRDLTVRADRINGLGTEVRTVFGEIFHGEPTALEGGKLIVGGPPPVAPPATPPTTPGPKAAATPGEAKPAGAASPPATEAAKPDQAKAEKETGGSPVKENATEKAKDTDAKDKPKEDTKDKPKEDTKDKPKEDTKDKPKEDTKDKPKEDAKDKPKEDTKDKPKEDAKDKPKDANAKEAPKPTPPPKVEPKARVPLDEVEGIAFEKALTLSGRVLGQPNLDFTRPGLEAPKDGAVAKSDTKTDDVLAPPPGTVTPAKIPKVEPKPNGICDLHLTLANLRTAAIKQVTINAQTDKGPAAWRLDTSDSRDWPLVVRRAGTETWADLFLEPPAGDLNGKDLTVNITYADGQNANATIKSDKRSDPKLAVDPTAPAPSLDARVYLTGDEQLFGKFEGLGEDSLRLQTPWGDRLTVPLARVIGIYMGLPEHKESAESFAKRLRTRGTEDLLLARSKDDEIVAIPGIAEGTKEDKLLFHFQEKTRSLPLKQVEGLVLAARPEPERPDGLRPTFSMAGGIVVSGLWKTLEAKTWKIETAWGQSLDLPAAEVRSVRFQGGQMTYLSDLEPSRVDETPFFTRRSPWRKDVNLAGAPLKVDGITYEHGLAVHSRSALTYDLNGEYTTFEAVVGFDDDAKKLGRVDCRVFADGKEIYANPDLRADAPPVKLSLPVAKAKQLKLLIDFGPDQDTGDRVIWANARLFRKPPPTKTEVAAKTAPADAAKPGSPEPQNTKTPTPTNTTTKPGSGK
>NC_019892.1|WP_015247329.1|4988945_4990667_-|hypothetical-protein
MSRPIIMRQSLGRSFSFRLAPLLALSLIGAWLPAALAEDDKPQPAIEVYDWSIWVTSPAQLTLNGTRVYKNAMPGVVGTSRPKLEGKELVGKFPIAPISVVQFFGEPSRDLDIDLRVKKGTLVAHWPPGSERAGRIQWFKSDLTKALAAGVPLGFLPEAHWLPQLRKVESALYHQRESRAERFLAYDTELAIPIPLKLRGGPDEYTLQNLTGLKLLDVAVIAPTDGGYRVGWLDELPSATPEGKDEGSVKKAKEKEEQERKKKPASEKANEVFEKAETDAKKEKDKDKEKDEPKPLPAEGDADVRARVDQILNRPINVNVEQAPRKEVLDLVTGQARVRYELDDKTLIKEEVDLGKTMSLKAPNIAARDALAEVLGTIGLSYRVTEDGSLFITTAARLAEDSGKKGAVIEGPPVKLTLSKPLKASDPSYRELTRDSYTRRLAAQGLRDEVIESLLGQYSEALFAPDGLIVLAHFSRDAIDDAVLLDVFPSPKKFVRTAALVMHGIDPRLQDKARELVQKLGDPAPKARETAETQLFDLGPVAVPVLEDALRDKDVEIVFRAERLLLKLNRQVP
>NC_019892.1|WP_015247328.1|4988439_4988682_-|hypothetical-protein
MIDTTTRRPLRVSTDGTAGPYIMVPVSQLDRVRRLLLDNKIPHRVDEDAISLGGNPAVVVIDLVRSDDAERTQAILDANA
>NC_019892.1|WP_015244773.1|4985504_4986929_+|IS1380-family-transposase
MATECNSTYLDFSILGHRQVLADFDGGAISSDGGALLLRQIEARTGIIRQFAACFTDHRDPDLVEHPLEHLLAQRVYGLALGYEDLNDHDDLRCDPLLATVVGKTDPTGQDRPRLRDRGKPLAGKSTLNRLELTPVGADGQSRYKKITCQTHEVERLFVTLFLQAHSRPPERIVLDLDATDDTVHGRQLGRFFHGYYKGYCYLPLYIFCGDHLLCARLRPSDIDASAGSVKSLKRIVSQIRQAWPQVKILIRADSGFCREEILRWCEDNGVDYLIGLAKNTRLTAAIATELAQARQQFEATKQPSRVFAELRYQTQKTWSRERRVVAKAEHLGKGANPRFVVTSLTVEERAAPPLYEQDYCGRGEMENRIKEQQLHLFADRTSAHTMRANQIRLFFSSIAYVLLEALRRLGLAGTAMAEAQCQTIRLKLLKIGALVRVTVRKVWVKFSSGCPYAEVFRRVHTNLARSGPLIPRC
>NC_019892.1|WP_015247327.1|4982751_4984527_+|EF-hand-domain-containing-protein
MTFATPCVALALALTVTAAAGPPEEAAKTEGEAERNVVFLGEERPVFLRLRVMAGDRPFDAAWLDSIRTIHACLDLDGDGKLTEKEADRGALAALVRLATGGATTLLRGELDVHPKDGVVSIDELAEALRPVIGPFRVQVGRLAINRTDALFDHLDRDKDGALTRTELAAIAGSLRRLDLDDNEMISATELEPFNSPTAMAVAGNAADRQARLIAVPPVVELVAGVSSLRLARLLLKKYDKGRGDVPGRPDGKLSPEEFAIDPDAFASADANHDGALSTEELRKFLAQAPVDLDLEINLSPDASGSGSGPGRATTRIRGDGGLAKGTEVRQLADGDVEIAVGRIRLDIHVDQGDAVAENARRIYQRLFKAADANKDGYLEGKELPAENNDAPVQVQVQGQVSPLAGLVKVIDRDGDGKLYEKELMEFADRQSEAARGRLVLTASDQGRAIFGILDLDRDRRLSAREVMRTVDRITSWDGDSDGRVTADEIPYHFQVNIARGELTGLIGGGGAGNNVVAPQAMMAAPKPAALTAGPDWFRQMDRNHDGDISRREFLGPRTEFDRLDRDKDGLIDAEEAEAGAGAASRGNAGP
>NC_019892.1|WP_015247326.1|4981387_4982755_+|DUF1501-domain-containing-protein
MNRPRPTYQVPPLTRRQVLRLAALGALGASSSGWIETLAANTAADPNRRKSCILLWMTGGPSQTDTFDPKPGHANSGPFKPIETTVPGMLLGPHLPQLARQAKDLALVRSMSSKEGDHGRATYYLRTGYLPQGPVRHPTLGSLVANEFEDKSAELPGFVSISPFRAFNPAAFGAGFLGPKCAPLIVGERPVGGGGGGDASTQPSLRVEDLDAPHDINRARADDRLQLMHTLGSDFLASRPGLAALSHQDAYQRAVKMMRSSAAKAFELDEEPAALQDAYGRNPFGQGCLLARRLVERGVPFVEVTLSSVDGSMAFGWDTHQQNFDAVEKLSGVLDAGWATLMTDLRSRGLLDSTLIVWMGEFGRTPKINENAGRDHFPNAWSTVLAGGGIRGGQVIGDTGADGEEAKDRPVMVPDLLATVVRSLGIDPMKQNVVDTGRPIRLVDPKANPIKELLG
>NC_019892.1|WP_015247325.1|4979685_4981269_+|DUF1549-domain-containing-protein
MLIRRAWVAVACLVTLGATAKGADVAGGQKEPAPSARDARSLAARIDAVLAARWADAKIKPAAVADDGEFLRRVSLDLVGKIPTAAEARDFLDDPSLDKRQALVERLLDSPAYTTRATELWRQLLLPEADTEDQARVVAGSFEAWLRRKVVEEAGYDRIVREILTTKLNDRNTEAMASRLDPSPAAYYVAKEGKPENLAAGAARVFLGVRLECAQCHNHPFAAWKRDDFWGFAAFFAGVPSPNSDGTAAVRMPRDAPPLRELTIPGTKKIVKAAHLDGSKPDWRPRAETREILAEWITAPQNPYFAKALVNRVWARFFGVGLIEPVDDLDLESDPEFGGLVNELAVQFRLHDYNLKYLIRVLTATQAYNLSSIAAPSESSSPMFAYMPVRGLSPGQLFDSLSQATGADAAGARGRFLDLFANRDERATEAQTTILQALTMMNGSHIAGATNPATGEVLGAVTKAPFLDTPGRIETLYLATLTRRPKPEELALLTRYVDRTESPEERAKALADVFWAILNGPEFHLNH
>NC_019892.1|WP_015247324.1|4978859_4979459_-|hypothetical-protein
MGIFGPSKDEVWRQLSHEIGAEFVEGRFWSGNRVQAYIAPWTITLDTHTVSTGHSHITYTRMRAPYVNPDGLRFTLYRKGLFSELGKLLGMQDIEVGDPDFDEAFIVKGTDEFKVRELFDDPQVRALALAQPTIHLSVKDDEGWFGAKFPKGVDELHFQVVGILKDGPQLKALFDLFAAILDRLCEMGAGRKEEPGVRL
>NC_019892.1|WP_015247323.1|4978347_4978692_+|RNA-binding-protein
MGKKLYVGNLTYNVNESDLEALFTPFGTVQSAQIIIDRDTNRSKGFGFVEMDTDAQAQAAIQGLNDRDHDGRNLTVNEAKPREPRSGGGGGGYGGGGRSGGGGGGYGGGGGGRY
>NC_019892.1|WP_015247322.1|4975152_4977882_-|PAS-domain-S-box-protein
MLSPARTPLLRYGGAVLAVLLATTVRWVLDPFIGAQFPLSTFFAALVFAAWYGGFGPALVAMSLCSPVITYFILPPYGSFFLDSYEGQVRFGAFLIAGLVIAVMGGTIRAARHRAETAAKEDRVKQRLLEQEVVERRGVEAALRVEKERLRVTLASIGDAVIVTDADGRVNFLNPIAEALTGWSTGEAAGQPLEAVFRIMNQETGKPIASPTLQALRGETTGGLADHAVLVARDGRERPIDDSAAPIRDESGRIVGVVLVFRDVTERRRADEIRRHLAAIVESSDDAILGTTLDGTITSGNSGAERLYGYTAEELVGQSAALLIPAERFDEFRATLNQIHQGMNTDHFESKRRHKDGTLIDVSVKVSPIRDGFDNVIGASTVARDITARKRAEKRLAESEQRFSRFMQHLPGLAWIKDLEGRYLYANEAALKAFQISRADLYGKVDDEVFPPETAALFRENDRKALAVEMGIQVVETLLQDDAIVHHSLVNKFLILGQDGNDTLIGGIATDITERMRMVESLREADLRKDEFLATLAHELRNPLAPIRNALHLMKPANRDCDDLERERAMAERQVTHLARLVDDLMDISRINRGKIELRKEVVELATIVGRATEAVKSSLEERGHSLCLSLSDRSIHLEADPTRLEQILGNLLNNAIKYTQPGGQISLIIEREHENVLIRVRDTGIGIEPEMLPRVFGMFVQAGHHTGHSHGGLGIGLSLVKTLVELHGGTIEATSRGPGAGSEFVVHLPILPGIPAASAIHRVPEDPPRPDAAVADTEQPTRRRILVVDDNLDAANSLARLLRRLHGQEVEVAHDGPAALEAAEAFRPELVLLDIGLPGMDGYEVARTLRDRPESATIRIIALTGWGQESDRQRSKEAGFDHHLVKPVDPDLLSTILRDYEMTPTAKA
>NC_019892.1|WP_015247332.1|4994207_4994726_-|hypothetical-protein
MRQNIRILGASALMSCLLQPAFAADPPAAAIALKMANVTDELNRTETGKPVQTEQKAIVQDLDELIASLEKQCQACKSGMKRNNPNKGMADSTISSGSGGIGTLLNPSDTGKDWGKLSGRERDRILQSMSEGFPPEYRTVLERYYRRLAEEKSSSSAQAKASSAPTKADETP
>NC_019892.1|WP_015247333.1|4994846_4996919_-|DUF4175-family-protein
MKSPSTHRRPGITAGRLALFLWIATATHVMPRLAQAQAKPDAAKAASVFDDEKADEKKPDDKKADDKKADDKKADDKKPNDKKADDKKADDEKKKADDEKKADEKQKADDEKMAKEKEQAKKATASERDSIGFTQENVAAQMTELEERMFRLSEALRGLEPENASRLRLALKFSREEQILDQMRETHKFMKDAQLSKAETEVRELVAKLEHLRNLLLAEDLDFQLKVARLRQMREALSQLDRIVKEEKRELGWSRFAIEQRKGLDRLAARRPDLEALARDQKALVADTKNAPPNGDAVKEAKAAIREREVKIRNTANALATDPLFADLQPPHLRRADAHLGDAVSLLEGTDVDAAVEAEEKALAMIGQELTRFDEQVAQSKQTIADGEFKRRQGDQSKNRAATDTLSEVSARLGDTGVALRKDLIRASGSMRTAEEGLGQTAAEPAADNQSAALEALTKSREELAQAVEKLLVELRKELQARLVAELTEMHELQAAIRETTQAQAPRVLQKSRTALIAVSGLSKKEAELGERTEHLLALVEETEFGIALPTTLRVLGREMRNIEGWLKAGDVAPRTIALEIRVEEDLLGLLQAIRRLPPGTPPPPGSPLPSDLRERERELNRLVAELKMIRMLQSRLNDDTVGVDKSRPDISELPPALRREVEALEASQDEIRESLAKIAERLENPDDNP
>NC_019892.1|WP_015247334.1|4996905_4999143_-|hypothetical-protein
MTTATDNTSLGSLREEQALLRSRLARLRRRLQLQMALEFALDAAVALVATAALLVFLDWWFRLNLPARLILLAAVLIGVVPFAILRALRGWRAARLDDLSLAVTLDRFRPGTGGRVADVLQLPDQLGESEESVSPAMIRLAVRQASEALAASDWASLWNRGRTLKRSAALLAALLVPTAFALIAPQAARLSAARWLQGSTERWPQRTYLSVVGLGDRNRILAPRDETFALEVRADLASVEPRKGHWIVSGRGEPLILRSLPKTPEVPKAVRVRERAAKGAVRDAVMVATGPSLFRYELPPSSTSTTFDLTGGDDWLGPVKVDRVDRPSLAATKLRVKEPGSPGNEFRAIDASAQHPVFLPDTEVELTLVGSEPIADAQLTVHPGQPPKLNRVDASTFTARWTLREAITLEIQLTSKATGLTSKPAFFSIGLLKDREPRVALRALGVGAHVTPVATIPLSLNATDDLGLSAVRLQLERTTAAGEKEKDKGEPKTTKKTVLLPLTTDGARAVLDHQARHDVELQADPPPLGTILRFVAEAEDKCARGVQVGRSAALQFQVVAPDELFYEILIRQRAERAKFVMLYEAAEKRATALSGAPSADDYATAMRGLNNGSRQLDLIAGRIADTLQEMKLNQVGSPKSHRLLQEGVIDPIRALNAGTVNELRSVLQSLTGTAPKAGADAESVRRLHGEVVAGMKIILDQMSQWESFVDVVNQVAEVIKMQQNVLQAAEKARESRTQEVFDEKP
>NC_019892.1|WP_015247335.1|4999201_5001655_-|VWA-domain-containing-protein
MSSIWKWLLGIDRSPGEVAPGGSTRLELSALPEGSAALAVLIAAVALTALLWKLYRRERRDLSQSRRTLLVGLRLLVLVAVAVMLIEPVLITVRRETVPSHLPIIIDDSESMKFADPYTDETKAAEVAAALELRSEGGKSPVDRLRETPRLDLIKASLRPNLAKLGRGREVFLSDLEAGVRSGTASSPSRNKKLDDLKPNRGVSPLGDALRDVLASHRGRPVAGIVLVTDGRSNAGEDPLKAVEAAIRQGIPVFPIAAGAEEGPRNVRLAEVEASPVVFARDPMTVGVMIEARGLKDAEGTVTLEQRINDNDWETIGDQRVALGEDGVLKRTTFRITPKVVGQYEFRARVGDAGPELTLEDNVATTPVRVVRQQIRLLMIAGSPSAEFQFLRNALQRDQHVESGIWLQHADPGYKQGGDRPIQRLPSDAAELGRYDALLLVDPDMRALGAQWPEMIMNFVGKEGGGLIFVPGELYSQQLFETDDAESEGGQWTRLLPVVREPGLFRTEAQVRLSTQTTYLLELTPEGRGDPIFEFNSDPIRNRAILTSLPGMYWSFPVTRARPGATVLARHGDPRMQNQYGRHVLLASQLYGPGRTVFIGFDSTYRWRYLSEDYFDGFWARLVDRVGRNKALGGRFPFQVHLGKSAYRVGDQVTVGVRFTEAAAVAEAAGLAAELEIGDQPAEPIHFERAIDDAELLTATFPAEKAGSYSLKITPATGAEEGSSVRVSTTTFRVEPPRREIDEPSLNRPLLADLARLTKGKVFDLPTISKLDDAIAMREVTRTLEDREELWDAPLLYATIILGLTSEWVLRKVFRMV
>NC_019892.1|WP_015247336.1|5001714_5003877_-|BatA-domain-containing-protein
MFTFLSPLLIWGALLGVIPIIIHLLNRRRFRRVEWAPMRYLKLTIQRNRRRIQIEQLLLLLLRIALPVLLFFFLARPLVNPTGLERWLGGGGRTSHVILVDDSLSMGYVSDGPPAFHRAREVAAALLAATRPGDRCTLVASSAPRTPVFLEVEGTRREELSGDALSIPQTETHAAWPAVLEGVDGVLQSCTYPTRQLTIITDLRKAGWEAGVSAIARRWNEQGLHVRIVDVGADEVANVALESLVPLDRTILAGAESRWEALIRNASPRVITGAKAILRVDDRPIELTLPEIAPRQTAKVPLTVRFPGSGPHDVSLQLPEDELPGDNQQWAAVPVKDSLLIRLVDGEPSSEPFGSEVDYLAAPLSIGVGDAEAWRVETVQEEDFLSPRFEPADVLVLANVAAPTAEQATQLARLVRGGMGLMIFTGAKLDHGLYNDLLYRTGEKLLPLPLKAQVDGEIRGLFIEPVRPSPIEKLLELRPSALERVTARQIMTVGDEADEAKVRVLARWNDVARSPAIIERVVGDGRVLFWTSTADRAGNDWPIEPSFVLAVREAVRGTARPTSLANTVTAGDRPRRVVRSSQQVVNAKVSPPGTGEPQALAAVPLADKAADDLGPAVAIDLPDTRRAGLYRLTWDEGPLGTQQDLFAANPDRRESALARIKERDLKALLQPLKLEVASARGDGIDAFSATGQEVWHQLAWGLLALLILEPILATWVGRSR
>NC_019892.1|WP_015247337.1|5003882_5004800_-|DUF58-domain-containing-protein
MPPSRTYSDPDTIAQIADLTLRSRRLAEGGISGQHRSPFHGFNIEFASYREYTPGDDLRRLDWRVFARSDRHYIKQYEEESNARVTFVVDASASMNYRGSKAALSKFDYGATLVVTLAMLLARQQDPVGLVLFDEDAGTVLAPSATQSQVTVMSGLLEGCVPARKTELGGMLRSLAGRIRRRGLLVIVSDLFTDLEAVYDSLNRLRFQGHEVLVLQVLDRDEIELPFDGPTLFRDIEGDEELYAEPGAFRLAYRRAMDEFLDGVSKECGARGYDHVRFFTDTPLSVSLSSFLHARQEAGGTGGRG
>NC_019892.1|WP_015247338.1|5004768_5005815_-|AAA-family-ATPase
MSTATEDLDLAELDELRTAHQQIRQQIARQIVGQDDVVDQLLIAVFARGHCILEGVPGLAKTLMVNSLARSLSLEFNRIQFTPDLMPSDITGTEVLYEDRTTGARELRFVHGPIFANLILADEINRTPPKTQAALLEAMQERQVTVGGHRHPLPDPFFVLATQNPIEQEGTYPLPEAQLDRFLFKIFINYPTPEEERRIYRITTGVEQPEITPLISGERIASLQRLVRRVPVSDQCIDYSMDLVRATRGPAHGGPKYIGDWVSWGAGPRAGQALILASKARAALAGRPSVSIDDIQTVARPVLRHRIVINYNAQAAGESSDSIIKRLLEDIPVRKGAADAAVADVFRS
>NC_019892.1|WP_015247339.1|5005830_5006970_-|terpene-cyclase/mutase-family-protein
MSRHDPHGDWRSGAGLARRAFLKSCGAAPLAGAGLGLLGCGLGFGPLVARSLLADEKEVLPKHVTPEALRAVTKGLDYLAAQQADDGSWNTGGGQAYPVAMTGLAGTALLAHGNSPTRGKYSRNLQGAVEFLVRCTTPTGLITGPSQDSGQPMHGHGFALMFLASVYGMITKESLRRQVAETIRKAVTLTSQGQSGAGGWTYIPGGGDEGSVTVTQVQALRAAQNAGFLVPKAVIDESMNYLEKCRTPEGGIQYSLSAGGGPRLAISAAAVATLYNAGQFESPIATDCLKYVWGQFRANEGWNKGGGHAFYSHLYAAQGFYMAGDEYWDQYFPATRDQLIAMQGGDGSWNGDGIGQVYGTSIAVVILQLPYKYLPVFQR
>NC_019892.1|WP_015247340.1|5006966_5007845_-|SIMPL-domain-containing-protein
MTRSSIVVIVVALALTGASRPAWAQFIADPSGGNLQGLAVTGKGTVSAKPNRLEIDIEVSASSELTADAIVKYRDAKRRLQEAFVALKLDNVTVEERGLNVDQKGAQMNPYFFDSQPSRKAKTEVQLTRKLIIKCADIRKLDEEALLQLVAKLLDVAQDAGGKVGATQDPFAAYYYGRYNQSNGLVRFILDDFDQLEEEAYGKAIADAEARAQRLAKLSRLKLGPVSGVRVTMSPGDRETPMYNYGIPQEEETPKQKRLESAKFQEIPVRVVLMVRFDSAPIPVETGRASTQ
>NC_019892.1|WP_015247341.1|5007837_5009949_-|PQQ-like-beta-propeller-repeat-protein
MKVVRLTIMTLLWLPMLALGQAKEKADEADKVTNDRPDRPLQMPPASSEVKEAFDDYDRFRRRGAWERALKSLYEIPEAQALRFVDGQKGFIIPVARKRREALGELSPEGQVAYRLFYDDEAKKLLDEADGPNELKTLERLYSAYFPTTVGDNAADRLGDLYFEMGRFDRAADCWLAVLRERPDTDLSPALIAVKAALALSRAGRHSEISVLRHDLADRYAGEKVTIGGQSAPAAEHLARFLGDGTAKNPQTAHSSAATAPGLDLTRVVPADWQMRFSESVIAGMTPAELVQWNANPLSAAVPTVAVEGSTLYANYLGHLFAIDLKTGKLIWRSASFHNIEIPAAQNQTRMVDPTRFTVVASKSHVWALTRDLKDPNQMAPFRLVCRRTDGGDVVWQSTDLPDYAQVDLGGTPILVGDTLFVVAKTSMNQQQGQSHQYVLAIRARDGKLLWKTEVGVFRQGQQYSYYGMPDTSPQPKLFHQAGAVYVDTHVGVLARLDAESGDLDWGYGYKTDPPNAMNRFFFFGPMPTESISSSGAPLRSGPALLAKGAKSEQIYALDADQMKVLWDRPIAKSARILGVDDQALFLGGPEISALDLQTRKLLWATRLPGGSSEGDVLVRAGGIWQLTPRGIFEIDPRTGQVRRIFRGDDTGADGGNLYLSGPLLLAVTNRTISAYPIATTAAVADGGVDAGAATPKTRISDD

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Crispr_ID: NC_019892_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_12

5056507-5056617

Orphan

Consensus_repeat	Method
GTTCACGCCCCGCTACCTACCAGTGCGAGAACGGGCGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_12

>merge|NC_019892|12|5056507-5056617|CRISPRCasFinder
GTTCACGCCCCGCTACCTACCAGTGCGAGAACGGGCGGGACGAAAGCCACGGGCAACGGGCTCAACATCGATGTTCACGCCCCGCTACCTACCAGTGCGAGAACGGGCGGG

>NC_019892|12|11|5056507-5056617|CRISPRCasFinder
GTTCACGCCCCGCTACCTACCAGTGCGAGAACGGGCGGG	ACGAAAGCCACGGGCAACGGGCTCAACATCGAT
GTTCACGCCCCGCTACCTACCAGTGCGAGAACGGGCGGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015247387.1\|5064257_5064548_-\|UBP-type-zinc-finger-domain-containing-protein	unknown	unknown	gnl\|CDD\|366940
NC_019892.1\|WP_015247377.1\|5051849_5052725_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|367364
NC_019892.1\|WP_015247381.1\|5058947_5059784_-\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|187578
NC_019892.1\|WP_015247378.1\|5052889_5056489_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_019892.1\|WP_015247376.1\|5051403_5051679_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020467383.1\|5047333_5048227_-\|DNA-adenine-methylase	unknown	unknown	gnl\|CDD\|223415
NC_019892.1\|WP_015247372.1\|5046422_5047286_-\|plasmid-pRiA4b-ORF-3-family-protein	unknown	unknown	gnl\|CDD\|377943
NC_019892.1\|WP_015247388.1\|5064764_5066348_-\|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379079
NC_019892.1\|WP_015247385.1\|5061569_5062283_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020467385.1\|5048698_5049007_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247380.1\|5058420_5058774_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380386
NC_019892.1\|WP_015247386.1\|5062566_5064216_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|273540
NC_019892.1\|WP_015247384.1\|5060873_5061107_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247379.1\|5056654_5057230_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|132044
NC_019892.1\|WP_020467384.1\|5048355_5048577_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247370.1\|5044555_5045065_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247375.1\|5049217_5050309_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015247383.1\|5060515_5060860_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247371.1\|5045283_5046405_+\|acyltransferase	unknown	unknown	gnl\|CDD\|224748
NC_019892.1\|WP_015247382.1\|5059844_5060477_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247387.1\|5064257_5064548_-\|UBP-type-zinc-finger-domain-containing-protein	gnl\|CDD\|366940	pfam02148, zf-UBP, Zn-finger in ubiquitin-hydrolases and other protein.	1.74235e-12
NC_019892.1\|WP_020467383.1\|5047333_5048227_-\|DNA-adenine-methylase	gnl\|CDD\|223415	COG0338, Dam, Site-specific DNA methylase [DNA replication, recombination, and repair].	8.67666e-30
NC_019892.1\|WP_015247381.1\|5058947_5059784_-\|NAD(P)H-binding-protein	gnl\|CDD\|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.95387e-57
NC_019892.1\|WP_015247378.1\|5052889_5056489_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.33168e-72
NC_019892.1\|WP_015247377.1\|5051849_5052725_-\|hypothetical-protein	gnl\|CDD\|367364	pfam03160, Calx-beta, Calx-beta domain.	8.17464e-19
NC_019892.1\|WP_015247372.1\|5046422_5047286_-\|plasmid-pRiA4b-ORF-3-family-protein	gnl\|CDD\|377943	pfam07929, PRiA4_ORF3, Plasmid pRiA4b ORF-3-like protein. Members of this family are similar to the protein product of ORF-3 found on plasmid pRiA4 in the bacterium Agrobacterium rhizogenes. This plasmid is responsible for tumorigenesis at wound sites of plants infected by this bacterium, but the ORF-3 product does not seem to be involved in the pathogenetic process. Other proteins found in this family are annotated as being putative TnpR resolvases, but no further evidence was found to back this. Moreover, another member of this family is described as a probable lexA repressor and in fact carries a LexA DNA binding domain (pfam01726), but no references were found to expand on this.	1.32669e-83
NC_019892.1\|WP_015247371.1\|5045283_5046405_+\|acyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	5.54784e-24
NC_019892.1\|WP_015247380.1\|5058420_5058774_+\|cupin-domain-containing-protein	gnl\|CDD\|380386	cd06981, cupin_reut_a1446, Cupriavidus pinatubonensis reut_a1446 and related proteins, cupin domain. This family includes bacterial and some eukaryotic proteins homologous to reut_a1446, a Cupriavidus pinatubonensis protein of unknown function that may be related to mannose-6-phosphate isomerase. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	2.57692e-58
NC_019892.1\|WP_015247386.1\|5062566_5064216_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	2.06346e-77
NC_019892.1\|WP_015247379.1\|5056654_5057230_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|132044	TIGR02999, Sig-70_X6, RNA polymerase sigma factor, TIGR02999 family. This group of sigma factors are members of the sigma-70 family (TIGR02937) and are found in a variety of species including Rhodopirellula baltica which encodes a paralogous group of five.	3.82002e-66
NC_019892.1\|WP_015247375.1\|5049217_5050309_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	6.85718e-35
NC_019892.1\|WP_015247388.1\|5064764_5066348_-\|right-handed-parallel-beta-helix-repeat-containing-protein	gnl\|CDD\|379079	pfam13229, Beta_helix, Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.	7.28306e-08
NC_019892.1\|WP_015247382.1\|5059844_5060477_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	0.0013667

>NC_019892.1|WP_015247378.1|5052889_5056489_-|serine/threonine-protein-kinase
MAAFDEEAVFQVARQIDRPDTRRLYLDQVCGLDADLRARVDALLRAHDEEQSFLERPAVAPGATGPVAPRETVGTHIGPYKLLQQIGEGGMGTVYMAEQTHPVRRRVALKVIKPGMDSKQVVARFEAERQALTLMDHVNIARVFDGGTTGTGLPYFVMELFTGVPITKYCDDNHLTPRQRLELFVPVCQAIQHAHQKGIIHRDVKPSNVMVTLYDGRPVPKVIDFGVAKATEHKLTDQTLFTQHGGVIGTLEYMSPEQAEMSALGVDTRSDVYSLGALLYELLTGSTPLSHKRMKQMAFAEIIRLIKVEDPPWPSTRLSNSGEALALISAQRQMESGKLTRLVRGELDWIVMKCLEKDRGQRYETANGFAADLLRYLADETVQACPPSARYRFSKFARRNKRALATAAVLAVAVLVVAGTLGWAVRDREARAQQTARERADREVAIQAKVATALNEAERWREQEKWPEALSAVKRAEGLLAGAGSDVLNESVRLFLRDVDFALHLEEIRLLASETVDGSFDWKRQDQRYEEAFRAYGIDVAGLSADKAARIRVRPRVAVAMGVALDDWAGVRGNIDPAGREGLTALAQTVDPDPWRNRVREARGRKDGNALGELAAAPELSRQPPTSLSVLAGALRQAGLADAQVGTLRLAQRQHLGDFWVNYNLAIALSKLGPAHRDASVAFATAAVALRPQSAAAHNVLGIALKVQGKFGEAVASYERALTLDPKHVPAHCNLGGALMAQQKLEEANARFRAAIALDPNSAPAHTGLGWALCDQGKLDEAVESGRRAIALDSKSASAHYNLGRALALQKKLDEAISCYRQAIALDPTFAKAHMNLGNELGNQGKWAEAVACYETATQLNPKDAVPHISLGVALSKQDKLEEAVASLKRAISLDPNYATAHYNLGVALSKQDKLDEAVASLKRTIALDPNYATAHYNLGNAYSEQRKLDEAVTSYRRAIELNRNYTSAHLNLGNELIRQGKLVDAVTSFKRVIELDSNHARAHNQLGIALRRLKRWDEAVTAHRTAIKLDPKYARAYHELGVTLQAQGELGEAITSYKRAIELEPNNTERLADLAWLLATCGEVKHRDPAGAVELAQRAVDLSPDDDFHQAALGVAHYRVGNWKNAVAALSRGMELRPGEAGVTWFYLAMAHWKLGDKGGARKFYDQGVKWVEKSKLKNEPAVQAEAADLMSVKETQK
>NC_019892.1|WP_015247377.1|5051849_5052725_-|hypothetical-protein
MWFRDHFSSLGHGCMPARHTTKARTPRQSRACLLDCEAFEDRIAPASLSVSDAVILEGNTGTQNAVVVVRLSAPSSTTVTVNYSTANGSAVAGSDYAATSGTLTFAPGQTSKSILVPVKGDRLAEQDETFSISLRGAKNATIRDGQGIVSILDNEPRFSIGTAVVEEGNAGTTLMTFTVMMAAPYDQEATVNFATQDYTATTADGDYVATAGTLRFAPGEMTKTITVVVNGDLRAEGDERFLVNLSGASANAQIVVAQANGYIADDDSAWYPPNYYEWNYYDSYSGGSAGW
>NC_019892.1|WP_015247376.1|5051403_5051679_-|hypothetical-protein
MSSPSFRPQVESLDGRCLPSGNPVMTIGDATPAALLGSTTEHNGSDRLGGLEFSAMRLQMSLDRLSKLHDTLSTILQRISRVQETIVGHLK
>NC_019892.1|WP_015247375.1|5049217_5050309_+|DUF1559-domain-containing-protein
MMARAPSSRFGFTLIELLVGIAIIAVLIALLLPAVQTAREVARRSQCINNLKQMGLAANTYQSANQSYPLRNATNTLGNSFGVIAPSSWGNFSGQAMMLPYLEQLAIFNACNFNLNPSPGFHPGGPMNTSALNARISTFLCPSDGLTISTGAGIRQNNYHGSMGTTTDPWYAGGVTGIFAHKISYDVSAVLDGTSNTIMWSEALVGSNNPRVYKRTAVGGTGTSHINNMLNPVVSSSESQVLSSNVLSGLAACNEVWARAARTATGTASNRGQFWGIGSPGFTFFNTVVTPNSKQYPWSACRTDTHPGSDYSSFINANSNHPGGVNVGFCDGSVKFIKDSISPPVYWALGTKAGGEVISSDSY
>NC_019892.1|WP_020467385.1|5048698_5049007_+|hypothetical-protein
MSTACAPKDSISLFVLLFVSLVIFFDRDVIGVDTVGSKVWMFCSVARGWGLYLEFRRNREFAHFVFARRVSLIRAKRFCLVGATFMGLGLVSIALVGWLLIG
>NC_019892.1|WP_020467384.1|5048355_5048577_-|hypothetical-protein
MIRQVFQVLRIDVKIVGGTEGQRAAAEPAIGLQLLEDSDASLFTLLPGTCQGGSGFGRSLRRPWLRTSPSLHS
>NC_019892.1|WP_020467383.1|5047333_5048227_-|DNA-adenine-methylase
MPLGVFEEPESWRVPPFKSQLLKWIGNKQRFAHHIVSYFPPRYGTYYEPFLGSASVLATLAPAHAIGSDLFRPLTEIWQTLHRSPETLLQWYTERRALMMSGEKVAQYEKIKASYNAGPNAADLLFLCRSCYGGVVRFRKGDGHMSTRCGVHTPIPTATFAQRVREWSHRTAGTTFLLADFEEAMSMAKAGDLVYCDPPYTDTQTILYGAQSFSLVRLFQVIGECKSRGVKVALSLDGTKRSGEKICTLAAPDGLFEQEARVHCGRSMLRRFQMGGQSLEGEVVADRLLLTYRDAND
>NC_019892.1|WP_015247372.1|5046422_5047286_-|plasmid-pRiA4b-ORF-3-family-protein
MAPKKSAKKETKSDYLRKVLGKNPNLEPDQINQGWTKSGHAGTISNALYYHVRAEMGIKSEWGWYPASEPAVKWVNPTSAGEAKSTPSRSGKVVGEVYQLKLTLLNVEPPIWRRIQVADCTLDRLHEHIQTAMGWTNSHMHHFIINGKYYGGPMLVGQSPYDDPHYTDSTTTMLSAILPANGKPFRFGYEYDFGDSWEHEILFEGRLPAEPKKQYPLCLEGARACPPDDVGGVWGYADFLEAIGDPHHENHKEMKSWIGGRFDPEAFSPATATRRMKQGLPDWRSTR
>NC_019892.1|WP_015247371.1|5045283_5046405_+|acyltransferase
MRRITELDALRPIWAILILLAHATEASWFHGWSRVDLFFVLSGFVLTYKMVVENDESRLRLSDFFRERFLRLLPAYYVLLIVVFAADGSRWDTDHLFGLLRAATFTANAPLYWSNTYPIRYSNLIIHAWSLEVEVLFCCLWPVVIRVFGRAGVMILAVILLIDSVYCRASGLHPWTFVARSDGLALGSLLALVLSRPGPIDRRRVGRWSIAAGLLGLGYLVWFRFWSERMTRSFDRPLEIWQSLAVLATNLSYAALIGMIATHAGHPSMGLLRTRWLNGLGRISYGIYLYSFVAIALAGEALGQGPTTRGWRTAWLAMTLAIVMAGLTRWLVERPLWTLARRPVKPLALGPVANARRPLANPLLNRPSGSEGE
>NC_019892.1|WP_015247370.1|5044555_5045065_+|hypothetical-protein
MHAEWADNLPAARRDGENGVRAFTATWQIAADLGLSAPPLPVLPPGTLIDELEQLSRDLLSAADTLDRDYTGMSWAIDRVAAKQKPSSAKGTVKDCHILGHALRLSTLLVAAGYPHSRLLVSSNRSDFAAPNATVFHPDIVPDAAAAGLRYAISLEAAVADLRVAGEIL
>NC_019892.1|WP_015247379.1|5056654_5057230_-|sigma-70-family-RNA-polymerase-sigma-factor
MGDVTQILAAVEAGDPTAAAELLPLVYDELRKLAAARMAAEQPGQTLQATALVHEAYLRLVGADASPHWNSRGHFFAAAAEAMRRILVEQARRKQAVKHGGDHPRVDLDDVEPAVAGPDLDLIALDEALELLARSAPRKAELVKLRFFAGLTIEQAAHVLGISTSTADNDWAYAKSWLRVALDGRPGDRPA
>NC_019892.1|WP_015247380.1|5058420_5058774_+|cupin-domain-containing-protein
MMAELTNLFSEIPADLPEELFQTLLQGAGFRIERIVSLGHVSPEGFWYDQESHEWVLLLTGAARLTLEGEPPIDLRPGAFVNIPARKRHRVDWTDPAQPTVWLAIHYEGAESAPAHS
>NC_019892.1|WP_015247381.1|5058947_5059784_-|NAD(P)H-binding-protein
MSESYLILGATGTVGRRVLATMRSLGHVVKGASRRNAAGPDFRRFDLLEPATHVSALEGVSTVMLISRPGDEEAHIHAEPFIDAMVGQRVGRVVVLSALGAEKRADFSLRKVEALVERSGMAWTHVRPNFFMQMLASPPLCTEIVTRNTLSLPLDDAKVAYVDADDVAAVLVRALIDPTLAHQSFEVNGPRSLDHDEVTALIARQVGREIRYVPLDEDSARRLLAIRGLSPPHVERVLRFYALTRQGECAASDTTVAALLGRPLGTFEAFVAANAAAW
>NC_019892.1|WP_015247382.1|5059844_5060477_+|TetR/AcrR-family-transcriptional-regulator
MNQKSNQRAATKQAFLTALEGELVSGRALTVEAIAGRAQANKALVYRYFGGLSGLLAAYAADDQFMPSAAELRALCDPNLDALPPRVRFAQCVTACVAALAKRPATVQILLRLPSFDPPTLAALREGRARGIADIRQAFGASDSGLGFDSELAFNLLIAGVCQILGARRLSWLHEETELPELVASVSRTVRGLLIPPSAGNDREGEGRQR
>NC_019892.1|WP_015247383.1|5060515_5060860_-|hypothetical-protein
MRHPRQPPEPGEPLRQRVERSIAQVEHQIWLLRHLLWWYLLPPALAILAFFAQVAWQARAGGWWTALIMAGLAFVEVIVFAGVYGLNQYAVRSELVPRRQELEALLVSLKDETP
>NC_019892.1|WP_015247384.1|5060873_5061107_+|hypothetical-protein
MYPAIQTSAGWKKLELYDGAKKLMELTKGPAEFTIQDLQPGYHAFSVLGTDGNGDVRPSNPVLVVVRKRLASSDPAK
>NC_019892.1|WP_015247385.1|5061569_5062283_+|hypothetical-protein
MRPLSGISIAILVIFAGTSANADSLFNSNPQFTVTDLGTSFSYQYGPDSKSILSVTNGAGNETYAFDKSPVEYSLWTSSGYGLSAVHTYKAGSYQASNSTYTNNAVVTSSVGWTNDKHQFPINDINVNGQVVGSIAGSARFTLPDLQHHVIPSLSDSSGMYAADMLDIYIPPVSGLSWLTSAFQIDDVGRILARGNNEHVYLLSPNPVPEPTPLMMFTTLAAAYGTLSIRRSFRRQA
>NC_019892.1|WP_015247386.1|5062566_5064216_-|FAD-dependent-oxidoreductase
MAEQDLHHIAFPTLDEAQIAKLGRCTGASAQRFQDGQMLFRVGDRNFKFFVIKSGLVEILDESGETAKTLTVHRPGGFTGDVSHLTGNPAVVSAVARGDCEVYEIASEGLKQILSRCPDLSDIILQAFIARRQLLREPGNFTGLRVIGSRYSQDTFRIRDFLAQNRVLFTWLDLEANPQVNLLLQQFGVSESDTPVVACGRLLLLRNPSTRKLAETIGIRRTPEQVVYDLAVVGAGPAGLAAAVYGASEGLNTVILERAAPGGQAGRSMRIENYLGFPTGLTGSELTDRAVLQADKFGALLSVPTPVTGLTFDQAYAVLQLDGGGSVVAKCLLIASGADYRRLGVEGCERLEGCGVYYAATPNEAQLCRGADVMVVGGGNSAGQAVVYLAGQARKVFLLIRGDNLYKNMSSYLARRIEQTDNVEVLCNTEVRQMHGDSHLTTVEVENTKTGEAKTLETPALFSFIGAVPWTDWLPNAIATDSRGFVRTGPSLKQSPSWVAPRDPFLLETSRPGVFAAGDVRSGSVKRVASAVGEGAMVVQFVHEYLKDL
>NC_019892.1|WP_015247387.1|5064257_5064548_-|UBP-type-zinc-finger-domain-containing-protein
MICEHEIGIDPVPPRTPEGCEECLKNGTPWVHLRLCLTCGHVGCCDSSPGRHATQHFHHTHHPVVASFEPGERWAWCYVDQAEQDVPEQALPYLKG
>NC_019892.1|WP_015247388.1|5064764_5066348_-|right-handed-parallel-beta-helix-repeat-containing-protein
MLSPVSPPTRRNRTGRRAWTLERLEERAVPATITVTSLADDGPGTLRAAITQANADTAADTILFAQDVRGTITLETALPDLSTTINIQGPGAKDLTVARNVWTSTPFSTFEVVQGADVILSGLTITGGTSLTAGGGINNSGELVVSNCTVSGNRGEYGGISNVDSGYLTIVDSTISGNRGPSFFGGGIYNSQSSTLAIHRSTISGNDSGTMGTSSGGGINNRGLMGITNSTISGNKTMGSGGGIYNGGTLTIISSTISGNATTDYRGSGEGGGIFNSGSMNILSSIVSGNKSSIGPMDISGAGNSLGYNIFFDVPDISLNPTDQTRTDAMLAPLADNGGPTFTQALLPGSPAIDSSVTINGVNTDQRNVPRPQGNAPDIGAFEAVGVVGARPTVVSLVRSSLRNQPTKLVLTFSAAMSSANAQDVSNYTLVPSGPAGRTRLHTRPIPITSAVYDPAAKTVTLTSRRLDARAYFRLTASGTPPAGLKSPNGVFLDGSGRGLPGSNYVAVIHGARALAPRENLAIKTGP

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Crispr_ID: NC_019892_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_13

5262274-5262382

Orphan

Consensus_repeat	Method
CCAGGGGTTTCACCCCTGGCTATTAACGGTCGCCCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_13

>merge|NC_019892|13|5262274-5262382|CRISPRCasFinder
CCAGGGGTTTCACCCCTGGCTATTAACGGTCGCCCCTCCGTGGCTGAGGATCGCTCATATATTGAATCATTTCCAGAGGTTTCACCCCTGGCTATTAACGGTCGCCCCT

>NC_019892|13|12|5262274-5262382|CRISPRCasFinder
CCAGGGGTTTCACCCCTGGCTATTAACGGTCGCCCCT	CCGTGGCTGAGGATCGCTCATATATTGAATCATTT
CCAGAGGTTTCACCCCTGGCTATTAACGGTCGCCCCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015247570.1\|5261058_5261694_-\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|372305
NC_019892.1\|WP_015247569.1\|5259861_5260962_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015247575.1\|5267366_5267702_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247574.1\|5266263_5266587_+\|H-type-lectin-domain-containing-protein	unknown	unknown	gnl\|CDD\|370507
NC_019892.1\|WP_015247572.1\|5263536_5264439_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247568.1\|5258187_5259213_+\|DUF1254-domain-containing-protein	unknown	unknown	gnl\|CDD\|227659
NC_019892.1\|WP_015247579.1\|5270859_5271645_+\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276
NC_019892.1\|WP_157579444.1\|5271785_5273372_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247573.1\|5265338_5265917_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_019892.1\|WP_020467528.1\|5259269_5259407_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247560.1\|5253974_5254550_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247571.1\|5262448_5263378_-\|S1/P1-nuclease	unknown	unknown	gnl\|CDD\|211382
NC_019892.1\|WP_154673930.1\|5259538_5259850_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224215
NC_019892.1\|WP_020467532.1\|5269674_5270142_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247577.1\|5268884_5269370_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_019892.1\|WP_015247576.1\|5268136_5268556_+\|protease-inhibitor-I42-family-protein	unknown	unknown	gnl\|CDD\|378179
NC_019892.1\|WP_015247562.1\|5254987_5255599_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|200466
NC_019892.1\|WP_015247565.1\|5256569_5257007_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247567.1\|5257688_5257997_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247563.1\|5255917_5256088_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225949

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247570.1\|5261058_5261694_-\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|372305	pfam12773, DZR, Double zinc ribbon. This family consists of a pair of zinc ribbon domains.	0.00460017
NC_019892.1\|WP_015247569.1\|5259861_5260962_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	7.59109e-47
NC_019892.1\|WP_015247568.1\|5258187_5259213_+\|DUF1254-domain-containing-protein	gnl\|CDD\|227659	COG5361, COG5361, Uncharacterized conserved protein [Function unknown].	4.07749e-33
NC_019892.1\|WP_015247573.1\|5265338_5265917_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.70038e-17
NC_019892.1\|WP_015247574.1\|5266263_5266587_+\|H-type-lectin-domain-containing-protein	gnl\|CDD\|370507	pfam09458, H_lectin, H-type lectin domain. The H-type lectin domain is a unit of six beta chains, combined into a homo-hexamer. It is involved in self/non-self recognition of cells, through binding with carbohydrates. It is sometimes found in association with the F5_F8_type_C domain pfam00754.	8.85931e-05
NC_019892.1\|WP_015247571.1\|5262448_5263378_-\|S1/P1-nuclease	gnl\|CDD\|211382	cd11010, S1-P1_nuclease, S1/P1 nucleases and related enzymes. This family summarizes both S1 and P1 nucleases (EC:3.1.30.1) which cleave RNA and single stranded DNA with no base specificity. S1 nuclease is more active on DNA than RNA. Its reaction products are oligonucleotides or single nucleotides with 5' phosphoryl groups. Although its primary substrate is single-stranded, it may also introduce single-stranded breaks in double-stranded DNA or RNA, or DNA-RNA hybrids. It is used as a reagent in nuclease protection assays and in removing single stranded tails from DNA molecules to create blunt ended molecules and opening hairpin loops generated during synthesis of double stranded cDNA. P1 nuclease cleaves its substrate at every position yielding nucleoside 5' monophosphates, and it does not recognize or act on double-stranded DNA. It is useful at removing single stranded strands hanging off the end of double stranded DNA and at completely cleaving melted DNA for simple DNA composition analysis.	3.35059e-57
NC_019892.1\|WP_154673930.1\|5259538_5259850_-\|hypothetical-protein	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	9.32821e-07
NC_019892.1\|WP_015247577.1\|5268884_5269370_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.06349e-13
NC_019892.1\|WP_015247562.1\|5254987_5255599_-\|hypothetical-protein	gnl\|CDD\|200466	cd11327, AmyAc_Glg_debranch_2, Alpha amylase catalytic domain found in glycogen debranching enzymes. Debranching enzymes facilitate the breakdown of glycogen through glucosyltransferase and glucosidase activity. These activities are performed by a single enzyme in mammals, yeast, and some bacteria, but by two distinct enzymes in Escherichia coli and other bacteria. Debranching enzymes perform two activities, 4-alpha-D-glucanotransferase (EC 2.4.1.25) and amylo-1,6-glucosidase (EC 3.2.1.33). 4-alpha-D-glucanotransferase catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. Amylo-alpha-1,6-glucosidase catalyzes the endohydrolysis of 1,6-alpha-D-glucoside linkages at points of branching in chains of 1,4-linked alpha-D-glucose residues. The catalytic triad (DED), which is highly conserved in other debranching enzymes, is not present in this group. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0.000424532
NC_019892.1\|WP_015247579.1\|5270859_5271645_+\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	2.04255e-31
NC_019892.1\|WP_015247576.1\|5268136_5268556_+\|protease-inhibitor-I42-family-protein	gnl\|CDD\|378179	pfam09394, Inhibitor_I42, Chagasin family peptidase inhibitor I42. Chagasin is a cysteine peptidase inhibitor which forms a beta barrel structure.	0.000470228
NC_019892.1\|WP_015247563.1\|5255917_5256088_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225949	COG3415, COG3415, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.52966e-09

>NC_019892.1|WP_015247570.1|5261058_5261694_-|zinc-ribbon-domain-containing-protein
MFCPECGTKGGGKFCVECGTKLSPPGPATAQAVEPPADWSREARHDRLIAHPEVQALLKDAAKQSGSRVSGEQLIKFYDKHLAKFNYGIAVGDVASIAAPLLTRLGIKTGKTRSEVVSAPIGHATVATLCSLTALGLEMKEVEQASDGCVIEAAIPPDLLVYQGTLVVTLTDLGDRSQVDAATKIGGQYFDWGKSSRLLDRLFTDIRAFRA
>NC_019892.1|WP_015247569.1|5259861_5260962_-|DUF1559-domain-containing-protein
MKPFRAKDRHDKEAGEWPGLTVTNADPTLMKGRGFTLIELLVVISVIGVLIALLLPAIQAAREAARRAQCVNNLKQLGLAGMNYESANSVLPSGMFRAVSDEAPVLTWGLSAFVRILPYLDASPLYHSANFSRQAITPANGTVASTGLSGLLCPSDPYVAEGHPDDFNYGAPVGFGIVQRHTSYGGCQGAWSLELIPQSPNSPAQVANMNGTIFCSSSVRLADISDGTGTTILFAEKSYGRVPSGDRGGACRWNVGIPSDSMVSAYYPLNGAVKGVPFLDGNILKWISSVGSFHPGGANVGFCDGSVRFVKDSIQSVPFDPKSGDVPAFRFDPVSGTYSIAPGTQLGVWQKLATRSFNEIVDADSF
>NC_019892.1|WP_154673930.1|5259538_5259850_-|hypothetical-protein
MVRPMGYADAEKRSSAGHLPGFSLPYYLGASAASYAVWVMFAAVGTVLGPTIGNVNDYGVDMAFPACSATSWVEPLTKANLADGSMFRGPVRAAAKMSANATI
>NC_019892.1|WP_020467528.1|5259269_5259407_+|hypothetical-protein
MPRTARASVGGLIAPTLNRGNRRQAAFPKAADAGQRLPSTSSVPA
>NC_019892.1|WP_015247568.1|5258187_5259213_+|DUF1254-domain-containing-protein
MRMTLTATAVLAVGWLTPLPAQEAKTPRVTVDNFTRAETDTYFARFVKDGGFGKFDHQRELTPIDQQAVIRMNRDTLYSQGVFDLDAAPVTITMPDAGKRYIAMQVIDENHFTTEVVYASGPHTLTRDKVGTRYVLALVRTFVNPNDAADVKAVHALQESLKAEQKETGKFEIPNWDPASLKQIRDALNSLLAANGGLDSTRMFGRKDEVDPVQHLLGTAGGWGGNPRADAFYAGAQPKQNDGKSAYRLTLKDVPVDGFWSVSVYNQDGFFERNARDAYTLNNVTAKPAADGSVTIHFGGNEHVPNYLPITPGWNYVLRMYRPRKEFLDGTWKIPEAIPGQ
>NC_019892.1|WP_015247567.1|5257688_5257997_+|hypothetical-protein
MPRTARASVGGGLIDHALNRDNRREAFFPQHADDSVFSLDLFGDYLMPHPFPLVLRPQGDGEVGRWMRRSRGGSGKSPIRSVSFSPCVWLFSGYASFMHVLF
>NC_019892.1|WP_015247565.1|5256569_5257007_+|hypothetical-protein
MAPPVSIPVRTQVPDDRGTTIVPDPKATGDMLQLQQAFAAALAAQDTRPAERRNHFAWLENTDAFKKKLVHFTGWYGGIIEVKEQPTGRVFVKIHISPWLYSDTLKTLQYDYVEETYEFFRDKVRLVDSDANVAKLEKQGYPVIR
>NC_019892.1|WP_015247563.1|5255917_5256088_-|helix-turn-helix-domain-containing-protein
MRPYSQDLRDRILETVARGEGSLRQIAQRFLVNVSTIVRLLKQYRQTGSAEPRSHI
>NC_019892.1|WP_015247562.1|5254987_5255599_-|hypothetical-protein
MNRRSRVFRPNLETEYLEPRRLLNGSIPADHPTDEQYDDLDAQIDQIGNESEPVAQLTITPLAMLDKDSEIAEINNLRNQFNQVIDSKIAIRQAAVEKAVALKAKVDVLNAAAVADFLANPGDPAAQADALKWGALVIKATNHLNGSQQSLQQMKDIKTQVNTIVDQVIANIKGTVYTMTDPDDPTNTQTFTEYTNEGYYTIA
>NC_019892.1|WP_015247560.1|5253974_5254550_+|hypothetical-protein
MNRRKIIVVVAAGFLLASGYWVASAASKRRTASRARGWVAESTLIPDPERLAEFQGLNHPARLYTVEPEPVRGKVKARTPEEDQRFREAATIVARARPLPPDRLQYFSWVDREDSPLRIQGWSAFVHQVSPLPGGWAITLKVWPKATRKGGVGVLVYSTYFEEYTWTQADGVLDYVKGVGDPVIPDPSYGR
>NC_019892.1|WP_015247571.1|5262448_5263378_-|S1/P1-nuclease
MRRIALTFAALVFLALPAYAWNKPGHMVTGAIAYAELKKNDPATLAKVVAILKKHPDINRWNDLINRLEIAPEDRDLFLFMQAARWPDDARGTTYDRPSHHFVNIPLKPGATGSPAIPVGDSILVAFDENMATLADNDASDSEKAVALCWIFHLVGDVHQPLHSVKLVTAQFPDPIGDRGGTRFFIKPKANGGTISLHQLWDGLIIGSQNFQTVRNTATELRERTGLQRSDLSEIAEKDFLKWCSVESFDTARDVAYSDGNGGPLQGGSTKPQAEVLPNGYLDKAKAAAERRVILAGYRLADLLGANLD
>NC_019892.1|WP_015247572.1|5263536_5264439_-|hypothetical-protein
MAAFVQVVDFMGFDGADSNAPWQMVPQGLTREVKLIQGNDQLEFTVTGGSGPPPPPTPAPLGSSSSERRHTAVIEGAKASQDGGAGLAIERKRLSPTDQIVVLRGWRVGSYEVQASDPKTGKPAARLLVDVVKQRTVPIAYYRLLFAEKWDTRVLNEQANRIIFDQAGITLKWLGEFDGAEGSTPITLPPGPVNLENAKTRTELRFFGNNPGAELMVYLTNFGVDDGNGMTLGDQTIIYSRKWKQPSEFPRMVETLAHEIGHFLSNGKNHDGKKDDLMFETSPHGRRIRKDRTMMFVRGL
>NC_019892.1|WP_015247573.1|5265338_5265917_-|class-I-SAM-dependent-methyltransferase
MKGRESGMPDEAYWESFFNSSCVVEQLDCAESQRGLVEFGCGYGLFTIPAARLAKGPVLTYDIDPAMIAATEAKAKAAGLANVTVEQRDFIGDGTGLADDSVDYVMLFNILHVEDPVSLLNEARRILAPGGKVGIIHWRSDIETPRGPSLAIRPRPEQCRAWSEQAGLRFVRYEPLTCCSYHFGLIVEKPSP
>NC_019892.1|WP_015247574.1|5266263_5266587_+|H-type-lectin-domain-containing-protein
MSTVKPAVHTSEHKIPELGSKHGAMVPGDALEFQGGAANKNTGTLQINFPRAFAHPPVVTISPYWAGQGQEVGHTDTLSSVTTTGFTVVSANQAANYYVMWLAVANK
>NC_019892.1|WP_015247575.1|5267366_5267702_-|hypothetical-protein
MPRFRFRMRGILVAVAVVGILLGLHQWMSRRARRFHAISESHRSRLSLVISGPVTSEGDFLGVPSVLDRDLKTVSRHRARKELWHYTMSVRYKRAAERPWLPVPPDPPEPY
>NC_019892.1|WP_015247576.1|5268136_5268556_+|protease-inhibitor-I42-family-protein
MSRQHGILGALATACLLATSWGIAYGAEHELGRLERIVKSGEYTAASGDLVEISVPSNPSTGPSNPAAKLKVSVHGDHLKKVGVYFAPPAKPLPGAPGEIRAYLTAHGNGTSKVTVTPISGSGQEGTPLEITLKVAKGE
>NC_019892.1|WP_015247577.1|5268884_5269370_-|helix-turn-helix-transcriptional-regulator
MLTEKIGETYSELPEAVKPALLALSILIDRIGSLPKADRDDLFELLQEWQKAETPEDQRSVQRAMEEILAQVPVTTRPLPLNDSAAMSPSSKTWAEHVGKAIRKLRCDLGWTQKQLAEKAGLPQSHVSRLENAEYTATNLTLTKIATALGVEVRAMDPCAD
>NC_019892.1|WP_020467532.1|5269674_5270142_-|hypothetical-protein
MPKALSAFGMAWGPTMADESQRKPVKIGVKEGGGPPPGYKWNVEILEQAFAEAMGFLNADQYCHLASQFRELAGQDEASQSQTVDVRPIEDFYELRDKGGILRRMNTRIFFFIHKKMRTIVILGAIKKENDGATPMGDKITMRRRKRLYLQADSR
>NC_019892.1|WP_015247579.1|5270859_5271645_+|pentapeptide-repeat-containing-protein
MNRKCALKLLRGGPEGIQEWNRRVGELTETLDLRGADLQGQDLREAFLRGPLRSGIKIDLAEADLRAADLRKANLSTSNLEKANLAGAILNRAAFRYTWLDGADLTGVDLRKTSMSDTDLRRVKLRNALLTGARFKGTCLIGADLAETDLSGTHFGNTEFGDADLRGVNLRHVDLFGSRFKEADLRGADLTGANVKNCHFDDTKLEGTIFTDAAFEWTIVSGVDLRKAIGLTLEQLNSSKWNKKTRFPAYLPSRPQKGQWI
>NC_019892.1|WP_157579444.1|5271785_5273372_+|hypothetical-protein
MMRNRLGVLGLVAVLFAGTASGQNVPKPSTSDSVNAEKETRYLAFQIFTHYSSDPKVAVLLNSGSREPVLPGTAALRNWVEDIKRRIGTVGDERTRLAVMLGPLCFEQDDAEVTRFIELAFRLALETDVAVGFHIDDSMFWAKRKDLWSDPKNVEALDWDGTPCTGRRLNWGKEPTAAPPQMCFNSKAIQREVQQRSALLGKAIQAGVKSLQEHKKPELFAGVIAGWETMIGQDFKTGKYLGYRALMNRGFSRERPPQDMNLEREKVVQEFIEHWTKGLAEAGVSPQKIYSHTAFLSRRAFNLGDDKAITYMKRDKESAYSQHNHFAPPSMAFGENHRPGFSTYPQPGLFEDIYEQMARHKQVGWASSEGTNMQPSSGPGQTGMDMETYLAKMFNHGATLVNLFSWGVGGDAMKTMGFRVVTEGEEAIRAYRKFLKGDALVEAKTEESLMERLPPKIHKIQKELPGWIEKAEVDSKKKAMSLMKQLQEQMKAKNFEEVEETANSLLKMMKGASAPAAAQDTPKEAGRG

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Crispr_ID: NC_019892_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_14

5269403-5269647

Orphan

Consensus_repeat	Method
GGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACA	CRT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACA	PILER-CR
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGA	CRISPRCasFinder

3 spacers

The CRISPR arrays of NC_019892_14

>merge|NC_019892|14|5269403-5269647|CRT,PILER-CR,CRISPRCasFinder
GGCTTCAATGGGGCCACGACTCGGAAGCCGGGGCAGACTACTCGCGATGTTTGTCCAGTCGCCACTGAATGGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACAAGGTATTGCGAGCCGTGCTTTCACACTGACGCCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGATATTCTCACGACTGCTCAGGTTCCTCAGACTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACA

>NC_019892|14|2|5269403-5269647|CRT
GGCTTCAATGGGGCCACGACTCGGAAGCCGGGGCAGACT	ACTCGCGATGTTTGTCCAGTCGCCACTGAATG
GGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACA	AGGTATTGCGAGCCGTGCTTTCACACTGACGC
CGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGATA	TTCTCACGACTGCTCAGGTTCCTCA
GACTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACA

>NC_019892|14|4|5269404-5269647|PILER-CR
GCTTCAATGGGGCCACGACTCGGAAGCCGGGGCAGACT	ACTCGCGATGTTTGTCCAGTCGCCACTGAATGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACA	AGGTATTGCGAGCCGTGCTTTCACACTGACGCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGATA	TTCTCACGACTGCTCAGGTTCCTCAG
ACTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACA

>NC_019892|14|13|5269404-5269645|CRISPRCasFinder
GCTTCAATGGGGCCACGACTCGGAAGCCGGGGCAGA	CTACTCGCGATGTTTGTCCAGTCGCCACTGAATGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGA	CAAGGTATTGCGAGCCGTGCTTTCACACTGACGCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGA	TATTCTCACGACTGCTCAGGTTCCTCAG
ACTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015247570.1\|5261058_5261694_-\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|372305
NC_019892.1\|WP_015247569.1\|5259861_5260962_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015247575.1\|5267366_5267702_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247572.1\|5263536_5264439_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020467532.1\|5269674_5270142_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247583.1\|5277413_5278121_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247573.1\|5265338_5265917_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_019892.1\|WP_015247574.1\|5266263_5266587_+\|H-type-lectin-domain-containing-protein	unknown	unknown	gnl\|CDD\|370507
NC_019892.1\|WP_015247571.1\|5262448_5263378_-\|S1/P1-nuclease	unknown	unknown	gnl\|CDD\|211382
NC_019892.1\|WP_015247586.1\|5284717_5285713_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_019892.1\|WP_154673930.1\|5259538_5259850_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224215
NC_019892.1\|WP_157579444.1\|5271785_5273372_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015244181.1\|5275064_5276450_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|373239
NC_019892.1\|WP_015247577.1\|5268884_5269370_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_019892.1\|WP_020467535.1\|5282619_5283132_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|224168
NC_019892.1\|WP_015247585.1\|5283387_5284611_-\|EstA-family-serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_019892.1\|WP_015247579.1\|5270859_5271645_+\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276
NC_019892.1\|WP_015247576.1\|5268136_5268556_+\|protease-inhibitor-I42-family-protein	unknown	unknown	gnl\|CDD\|378179
NC_019892.1\|WP_015247582.1\|5277070_5277364_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247581.1\|5273805_5274717_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247570.1\|5261058_5261694_-\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|372305	pfam12773, DZR, Double zinc ribbon. This family consists of a pair of zinc ribbon domains.	0.00460017
NC_019892.1\|WP_015247569.1\|5259861_5260962_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	7.59109e-47
NC_019892.1\|WP_015247585.1\|5283387_5284611_-\|EstA-family-serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.96629e-57
NC_019892.1\|WP_015247573.1\|5265338_5265917_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.70038e-17
NC_019892.1\|WP_015247574.1\|5266263_5266587_+\|H-type-lectin-domain-containing-protein	gnl\|CDD\|370507	pfam09458, H_lectin, H-type lectin domain. The H-type lectin domain is a unit of six beta chains, combined into a homo-hexamer. It is involved in self/non-self recognition of cells, through binding with carbohydrates. It is sometimes found in association with the F5_F8_type_C domain pfam00754.	8.85931e-05
NC_019892.1\|WP_015247571.1\|5262448_5263378_-\|S1/P1-nuclease	gnl\|CDD\|211382	cd11010, S1-P1_nuclease, S1/P1 nucleases and related enzymes. This family summarizes both S1 and P1 nucleases (EC:3.1.30.1) which cleave RNA and single stranded DNA with no base specificity. S1 nuclease is more active on DNA than RNA. Its reaction products are oligonucleotides or single nucleotides with 5' phosphoryl groups. Although its primary substrate is single-stranded, it may also introduce single-stranded breaks in double-stranded DNA or RNA, or DNA-RNA hybrids. It is used as a reagent in nuclease protection assays and in removing single stranded tails from DNA molecules to create blunt ended molecules and opening hairpin loops generated during synthesis of double stranded cDNA. P1 nuclease cleaves its substrate at every position yielding nucleoside 5' monophosphates, and it does not recognize or act on double-stranded DNA. It is useful at removing single stranded strands hanging off the end of double stranded DNA and at completely cleaving melted DNA for simple DNA composition analysis.	3.35059e-57
NC_019892.1\|WP_015247586.1\|5284717_5285713_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.76099e-17
NC_019892.1\|WP_154673930.1\|5259538_5259850_-\|hypothetical-protein	gnl\|CDD\|224215	COG1296, AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism].	9.32821e-07
NC_019892.1\|WP_015247577.1\|5268884_5269370_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.06349e-13
NC_019892.1\|WP_020467535.1\|5282619_5283132_-\|N-acetyltransferase	gnl\|CDD\|224168	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane].	1.11547e-39
NC_019892.1\|WP_015247579.1\|5270859_5271645_+\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	2.04255e-31
NC_019892.1\|WP_015247576.1\|5268136_5268556_+\|protease-inhibitor-I42-family-protein	gnl\|CDD\|378179	pfam09394, Inhibitor_I42, Chagasin family peptidase inhibitor I42. Chagasin is a cysteine peptidase inhibitor which forms a beta barrel structure.	0.000470228
NC_019892.1\|WP_015244181.1\|5275064_5276450_+\|IS4-family-transposase	gnl\|CDD\|373239	pfam14706, Tnp_DNA_bind, Transposase DNA-binding. This domain occurs at the C-terminus of transposases including E. coli tnpA. TnpA encodes a transposase and an inhibitor protein, the inhibitor only differs from the transposase by the absence of the N-terminal 55 amino acids, which includes most of this domain. This domain consists of alpha helices and turns, and functions as a DNA-binding domain.	3.82088e-18

>NC_019892.1|WP_015247577.1|5268884_5269370_-|helix-turn-helix-transcriptional-regulator
MLTEKIGETYSELPEAVKPALLALSILIDRIGSLPKADRDDLFELLQEWQKAETPEDQRSVQRAMEEILAQVPVTTRPLPLNDSAAMSPSSKTWAEHVGKAIRKLRCDLGWTQKQLAEKAGLPQSHVSRLENAEYTATNLTLTKIATALGVEVRAMDPCAD
>NC_019892.1|WP_015247576.1|5268136_5268556_+|protease-inhibitor-I42-family-protein
MSRQHGILGALATACLLATSWGIAYGAEHELGRLERIVKSGEYTAASGDLVEISVPSNPSTGPSNPAAKLKVSVHGDHLKKVGVYFAPPAKPLPGAPGEIRAYLTAHGNGTSKVTVTPISGSGQEGTPLEITLKVAKGE
>NC_019892.1|WP_015247575.1|5267366_5267702_-|hypothetical-protein
MPRFRFRMRGILVAVAVVGILLGLHQWMSRRARRFHAISESHRSRLSLVISGPVTSEGDFLGVPSVLDRDLKTVSRHRARKELWHYTMSVRYKRAAERPWLPVPPDPPEPY
>NC_019892.1|WP_015247574.1|5266263_5266587_+|H-type-lectin-domain-containing-protein
MSTVKPAVHTSEHKIPELGSKHGAMVPGDALEFQGGAANKNTGTLQINFPRAFAHPPVVTISPYWAGQGQEVGHTDTLSSVTTTGFTVVSANQAANYYVMWLAVANK
>NC_019892.1|WP_015247573.1|5265338_5265917_-|class-I-SAM-dependent-methyltransferase
MKGRESGMPDEAYWESFFNSSCVVEQLDCAESQRGLVEFGCGYGLFTIPAARLAKGPVLTYDIDPAMIAATEAKAKAAGLANVTVEQRDFIGDGTGLADDSVDYVMLFNILHVEDPVSLLNEARRILAPGGKVGIIHWRSDIETPRGPSLAIRPRPEQCRAWSEQAGLRFVRYEPLTCCSYHFGLIVEKPSP
>NC_019892.1|WP_015247572.1|5263536_5264439_-|hypothetical-protein
MAAFVQVVDFMGFDGADSNAPWQMVPQGLTREVKLIQGNDQLEFTVTGGSGPPPPPTPAPLGSSSSERRHTAVIEGAKASQDGGAGLAIERKRLSPTDQIVVLRGWRVGSYEVQASDPKTGKPAARLLVDVVKQRTVPIAYYRLLFAEKWDTRVLNEQANRIIFDQAGITLKWLGEFDGAEGSTPITLPPGPVNLENAKTRTELRFFGNNPGAELMVYLTNFGVDDGNGMTLGDQTIIYSRKWKQPSEFPRMVETLAHEIGHFLSNGKNHDGKKDDLMFETSPHGRRIRKDRTMMFVRGL
>NC_019892.1|WP_015247571.1|5262448_5263378_-|S1/P1-nuclease
MRRIALTFAALVFLALPAYAWNKPGHMVTGAIAYAELKKNDPATLAKVVAILKKHPDINRWNDLINRLEIAPEDRDLFLFMQAARWPDDARGTTYDRPSHHFVNIPLKPGATGSPAIPVGDSILVAFDENMATLADNDASDSEKAVALCWIFHLVGDVHQPLHSVKLVTAQFPDPIGDRGGTRFFIKPKANGGTISLHQLWDGLIIGSQNFQTVRNTATELRERTGLQRSDLSEIAEKDFLKWCSVESFDTARDVAYSDGNGGPLQGGSTKPQAEVLPNGYLDKAKAAAERRVILAGYRLADLLGANLD
>NC_019892.1|WP_015247570.1|5261058_5261694_-|zinc-ribbon-domain-containing-protein
MFCPECGTKGGGKFCVECGTKLSPPGPATAQAVEPPADWSREARHDRLIAHPEVQALLKDAAKQSGSRVSGEQLIKFYDKHLAKFNYGIAVGDVASIAAPLLTRLGIKTGKTRSEVVSAPIGHATVATLCSLTALGLEMKEVEQASDGCVIEAAIPPDLLVYQGTLVVTLTDLGDRSQVDAATKIGGQYFDWGKSSRLLDRLFTDIRAFRA
>NC_019892.1|WP_015247569.1|5259861_5260962_-|DUF1559-domain-containing-protein
MKPFRAKDRHDKEAGEWPGLTVTNADPTLMKGRGFTLIELLVVISVIGVLIALLLPAIQAAREAARRAQCVNNLKQLGLAGMNYESANSVLPSGMFRAVSDEAPVLTWGLSAFVRILPYLDASPLYHSANFSRQAITPANGTVASTGLSGLLCPSDPYVAEGHPDDFNYGAPVGFGIVQRHTSYGGCQGAWSLELIPQSPNSPAQVANMNGTIFCSSSVRLADISDGTGTTILFAEKSYGRVPSGDRGGACRWNVGIPSDSMVSAYYPLNGAVKGVPFLDGNILKWISSVGSFHPGGANVGFCDGSVRFVKDSIQSVPFDPKSGDVPAFRFDPVSGTYSIAPGTQLGVWQKLATRSFNEIVDADSF
>NC_019892.1|WP_154673930.1|5259538_5259850_-|hypothetical-protein
MVRPMGYADAEKRSSAGHLPGFSLPYYLGASAASYAVWVMFAAVGTVLGPTIGNVNDYGVDMAFPACSATSWVEPLTKANLADGSMFRGPVRAAAKMSANATI
>NC_019892.1|WP_020467532.1|5269674_5270142_-|hypothetical-protein
MPKALSAFGMAWGPTMADESQRKPVKIGVKEGGGPPPGYKWNVEILEQAFAEAMGFLNADQYCHLASQFRELAGQDEASQSQTVDVRPIEDFYELRDKGGILRRMNTRIFFFIHKKMRTIVILGAIKKENDGATPMGDKITMRRRKRLYLQADSR
>NC_019892.1|WP_015247579.1|5270859_5271645_+|pentapeptide-repeat-containing-protein
MNRKCALKLLRGGPEGIQEWNRRVGELTETLDLRGADLQGQDLREAFLRGPLRSGIKIDLAEADLRAADLRKANLSTSNLEKANLAGAILNRAAFRYTWLDGADLTGVDLRKTSMSDTDLRRVKLRNALLTGARFKGTCLIGADLAETDLSGTHFGNTEFGDADLRGVNLRHVDLFGSRFKEADLRGADLTGANVKNCHFDDTKLEGTIFTDAAFEWTIVSGVDLRKAIGLTLEQLNSSKWNKKTRFPAYLPSRPQKGQWI
>NC_019892.1|WP_157579444.1|5271785_5273372_+|hypothetical-protein
MMRNRLGVLGLVAVLFAGTASGQNVPKPSTSDSVNAEKETRYLAFQIFTHYSSDPKVAVLLNSGSREPVLPGTAALRNWVEDIKRRIGTVGDERTRLAVMLGPLCFEQDDAEVTRFIELAFRLALETDVAVGFHIDDSMFWAKRKDLWSDPKNVEALDWDGTPCTGRRLNWGKEPTAAPPQMCFNSKAIQREVQQRSALLGKAIQAGVKSLQEHKKPELFAGVIAGWETMIGQDFKTGKYLGYRALMNRGFSRERPPQDMNLEREKVVQEFIEHWTKGLAEAGVSPQKIYSHTAFLSRRAFNLGDDKAITYMKRDKESAYSQHNHFAPPSMAFGENHRPGFSTYPQPGLFEDIYEQMARHKQVGWASSEGTNMQPSSGPGQTGMDMETYLAKMFNHGATLVNLFSWGVGGDAMKTMGFRVVTEGEEAIRAYRKFLKGDALVEAKTEESLMERLPPKIHKIQKELPGWIEKAEVDSKKKAMSLMKQLQEQMKAKNFEEVEETANSLLKMMKGASAPAAAQDTPKEAGRG
>NC_019892.1|WP_015247581.1|5273805_5274717_+|hypothetical-protein
MGGNGVRVPHFVIALAYLLSSLAIPSVSYAADLKPYPLPPAARADIEKLAASSNVLILGETHGTQEVPELTASLLEPLAKLDYHILAIEVPNKEQASLLAWAHGKTERVPDFFANPSGDGRGNAQLLSLVRIAVSPPFRWQVICFDDTESMLEQQRLILMQKKPTGGAEAPQLTAEDGIALWRARDAAMAANLLRETKSLKTTSKILAVCGNLHARVTNDMQDPDLSKLWPSFAGMLKQGQPAWRVSSVNIEFYRGAFFNEGKVRTIQGRPLEHAVVRSADQTGWNLELSLPEATPATFHFSK
>NC_019892.1|WP_015244181.1|5275064_5276450_+|IS4-family-transposase
MSPTLTDPEAWAQANFAGADLGDKRRETRLIRLATQIAVDSSASLPKATGNWDDLRAAYRLLDSSAVNFRAIAEPHWRSIRETSPEMALILDDTTEIDFGCTRQIQGVGPVGTGTGQGFMIHSGLMVSHKDEVVYGLAGQILFHRKPVPKGESRTQRRKRDRESEVWGKLIELIGSPPQNTRWVHVMDRGSDDFEVYCRAQRQGVDWVGRVKSLHRRVQGADGLERPLQEELESVPQAGCFTLKLRSRPGLPARTAKLTVTFVRATMLVPRQPADSLKGLDPQPIAQYVVCVREVDPPASVKEPIEWVLYTSLEVACLEDALRIISYYEKRWLIEEWHKALKSGCSAADHQLKASHRLEALTGLLSVVAVRLLQLKGIARSEPERPAIEAAPPKYVAVLRAFRRTTEALPWGTYQFFRELAKLGGFLGRKGDGEPGWQTIWRGWMKLQAMVQGAELDLRLE
>NC_019892.1|WP_015247582.1|5277070_5277364_+|hypothetical-protein
MAFWPIVGWSSVCLGCVAALYGLHRLGLRLEEQGYIYYWYKKPSGSAAGCFVALQRAVEPQVQHVEQARAEQNRDGDDESAGRRRAQEAEEGQEPMN
>NC_019892.1|WP_015247583.1|5277413_5278121_-|hypothetical-protein
MIARFAVVILASQWIACLCASAQSHLEPENGILNATDSTWNSSKRIREVLLKEATYYHLARMVCLPSFDEPEWVVTVVRQDGEELDAPHTYFVEYVGAETKLFLAKGAQDVQVKRSRAPLDRSTAESLNKTWRRMLRSTRYPKDPRLGADGVNYHFSRFVPLIDRGRNDPLAGWEQGKIWTPDEDSLCGELVAIGEELKRYAVALPADRDRIHDRIRAKEHQLKAKLNRESKTAP
>NC_019892.1|WP_020467535.1|5282619_5283132_-|N-acetyltransferase
MFIRDATEADLPAIVDIYNQSIPAGWSTADTQPITVADRLDWFRKFDPARRPIWVAEVDGQIAATAYLSSFYGGRAAYDATAEVSLYIATAFQRRGIGRQFKQWVIAECPRLGVTTLLSMHFDHNEATRRINESLGFQPLGHLTEIALVQGTKRGLVISALRIPPKPETP
>NC_019892.1|WP_015247585.1|5283387_5284611_-|EstA-family-serine-hydrolase
MSNVDGLVEDGWGQVADTFRANFKEGKDLGAACCVYVDGRAVVDLWGGLADREKNRPWERDTVALVASTTKGATAICAHLLVQRGQLDLDAPVIRYWPEFGAAGKEKIPVRWLLSHQAGLPYVDTPVTFEEACAWDPLIRALEVQKPLWTPGTEHLYHAMTYGFLVGEVIRRITGRSPGTFFAEEIAQPLGLSAWIGLPEEVEPRIARIEAAPFPYKSMEDLAPDFAKLMGLDLAVAVTLVKDVYGPGSAFMKAGAVGDVTGENVLSRAYRAAEFPGANMFANAHSIARMYAATVSDVDGIRLLQPDTVAAMTVAQTDRTRMHGAPPELLPATKNLFNMSLGFVRSAPPVMSMFGPASFGHPGSGGSLGAADPESRVGFGYVPNLWAATMVDPRAIELTSAVAKCLG
>NC_019892.1|WP_015247586.1|5284717_5285713_-|alpha/beta-hydrolase
MSQATAPPHRFSISAGRDDRPANTLGRARGRRFRPLAAFSLLTALTALSCTRAEDPAATAPNRQSVDVGGYKLTLLTRGQGTPTVVIEPGMGLAAVESDEWTVVCEEIAKTNRVCLYDRAGLGTSDPAPTRPRTSQDIARDLHALLINAKVPGPYVLVGHSIGGLNVRVFADLYPDEVAGVVLVDVTHPDQESKWLASLPAESPEELPALKKSRELLTSRLERGSDNPDGMDVVTSREQVRSTSTLGDKPLAVLTHSPDWKMVPDLPDAILKPLEQISQDLQASLPALSTNSSHKVAKKAGHAIHLDEPSLVIEAVREVLEKANGNTAKLR

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Crispr_ID: NC_019892_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_15

5278274-5282042

Orphan

Consensus_repeat	Method
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CRISPRCasFinder
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CRT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	PILER-CR

51 spacers

The CRISPR arrays of NC_019892_15

>merge|NC_019892|15|5278274-5282042|CRISPRCasFinder,CRT,PILER-CR
CCTCCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTTGGAGTTGAGCCGACCGACCGGGGCGAGAATGCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGATGTTCACGGCTTGGGCTCCTGGCCAGCGTACGTGATCGTGCTTCAATGGGGCCACGGCTCGGAGGCCGAGGAAGACGGTGGGCATCGACACCAACGATCCCGACTTGCACAAGCTTCAATGGGGTCACGGCTCGGAGGCCGTGGAAGACGACGTCACCGCTGCTGCGGGCAAGAAACTCTACTGGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACAGAGTAATGCATGGCCTGTAAAGTTGGCATGTCGACGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACTGACCGAGAATCTGCGGATCTCCGGAAATATCCTCACGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGTCTGCACAGGCATCCGAAAAGCTCAGCAACAAAGGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGCTCAACGTTGCGTCCTGGCCGAGTCGGAATAGAGTGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACCAGCCTCGCGGAGGAGCCGGAAGAGGCCGCTCAATTGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACAGGACCCGAAATGGACCCTCGATCCGGCAAACAAGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGTCACACCTCGGTGGACGGAGTAATCCCCGGCTGGGTTGCTTCAATGGGGTCACGGCCCGGAGGCCGTGGAAGACCTTTTATGCTCGCGTGGCCTGGTTGGTTGTCGTCACGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGCTCCTGCCGTGACATCCCTGAAAAAGGCTACGCAAGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACTCACTTGGACGATTTCAAAAAGGCCCTCGGGATAGCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACAAGCTCCGACGCAATCCACTGTCCGCTGGTGTGGAGGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGCCGTTTCGGCTCCAAACAACGGTTTCGTATACCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACACGGCGTCACAAACGCGGCAACAACCACATTTTGCACAGGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACCACGCCATCCCTTTGCGGGTCAGAGTGTCAGTGGAGCGGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACCGAGACCTGGCCGTCCAGATCGACCGGCGTGACTTGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACAACAATTCGCCGGACCACAACCCGGGGATCCTCGAGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACTCGCGTCGGGCGCGGCTGTATATACCGCATGGAACGGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACAAGCTCAAGCCGGCTACCTCAACGGACGCACAATGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACCCGATCTGGAGAAGAGAGTTCTAAAAGGCTTCGACGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACCGGAAAGGTGCAGCAGAACGCCGAGGCTTACATCGCCGAGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACACTGGCCGAGGATCCGGCCCACAATATTCGAAATGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGAGGCTGGGAAAAATCTGGAGGACAGCAGCAGCCGGCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACCGCCGCTGGAAGAGTCCTCGACCCCATCGAGTCCCCCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACATCAGGTTGAGAGTTGCCGTCTTCTTGGCGTAATCAGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGGGAAAGTTCTACGGTGTGAACATCGAGATCGAAGTCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACCCTGCTCCTCTCACTGAAGGCGGATGCGATGCACATTGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGACCGCGTATTGCCACTCGTCGTAGCAGAGCGATGTGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACTTCCAGGGTCCATGTCGAAACCTGCTCAAACCAGGAAAGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGATGCGGCCAGGCAGCGACGTTGGCCGAGTTGTGGCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGGCCTGGCTGACAAGACCTGGCTCGAGAAGAACTAGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGAGTTGGTCGGCAAGCCGTTGGCCGCGCGTGAAGACGCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACAGGAGAAGAGGAACTGACTCAGGCCGGCGTACGTGTGGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGTCGCTCCAGGGTGACCGCTACTTGGTTCAGGGCTGCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACTTCTCGGCATCACCCAGCTTGGCATGCCAAGCGCCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACCGGGGACTCGATCCCCGAGCTGACCAAGCGGGTGCAGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACACAGACACCTCCGGGACAGGTTTGCGGGGCTTGTGGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGCCGGAGTCGAGGTTGGCACGGATCGGGATGGTCAAGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGGCGATTATCCTGTTAACAAGATCTGGAGATTTACGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACCAAGACGACGGCTATAACGTCGTTATAGGGTTAACGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACTGTCGTCAGGCTGTACTACTGTCACGGCCTGACCATGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGTCAGCGAGCGACCAGTGCTTCGCGTGACAGGCCGATCGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGATTCGGAGCAGCGTGCGGTTGCAGCCTGCCGTAATGGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACCGACCAGGCCGATGCCAACCCGGAGCTCAACTGATGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACTTTCGTCCTCGATCTCGGCGAACTCGTGCGTTCTCAGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGGCGATATCGCCCTTCGCACGCTGGTCGAAGTCGACGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGGCGATCCCGAGCCGCAAGGGACCGGTCCAGGCCTGGGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACGGGATTGCAAGTAGCTATCACCTGGTCCCGAGGATCTTGCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC

>NC_019892|15|14|5278274-5282042|CRISPRCasFinder
CCTCCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTTGGAGTTGAGCCGACCGACCGGGGCGAGAATGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAT	GTTCACGGCTTGGGCTCCTGGCCAGCGTACGTGATCGT
GCTTCAATGGGGCCACGGCTCGGAGGCCGAGGAAGAC	GGTGGGCATCGACACCAACGATCCCGACTTGCACAA
GCTTCAATGGGGTCACGGCTCGGAGGCCGTGGAAGAC	GACGTCACCGCTGCTGCGGGCAAGAAACTCTACTG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AGAGTAATGCATGGCCTGTAAAGTTGGCATGTCGAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TGACCGAGAATCTGCGGATCTCCGGAAATATCCTCAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GTCTGCACAGGCATCCGAAAAGCTCAGCAACAAAG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GCTCAACGTTGCGTCCTGGCCGAGTCGGAATAGAGT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CAGCCTCGCGGAGGAGCCGGAAGAGGCCGCTCAATT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AGGACCCGAAATGGACCCTCGATCCGGCAAACAA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GTCACACCTCGGTGGACGGAGTAATCCCCGGCTGGGTT
GCTTCAATGGGGTCACGGCCCGGAGGCCGTGGAAGAC	CTTTTATGCTCGCGTGGCCTGGTTGGTTGTCGTCAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GCTCCTGCCGTGACATCCCTGAAAAAGGCTACGCAA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TCACTTGGACGATTTCAAAAAGGCCCTCGGGATAGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AAGCTCCGACGCAATCCACTGTCCGCTGGTGTGGAG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GCCGTTTCGGCTCCAAACAACGGTTTCGTATACC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	ACGGCGTCACAAACGCGGCAACAACCACATTTTGCACAG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CACGCCATCCCTTTGCGGGTCAGAGTGTCAGTGGAGCG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CGAGACCTGGCCGTCCAGATCGACCGGCGTGACTT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AACAATTCGCCGGACCACAACCCGGGGATCCTCGA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TCGCGTCGGGCGCGGCTGTATATACCGCATGGAACG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AAGCTCAAGCCGGCTACCTCAACGGACGCACAAT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CCGATCTGGAGAAGAGAGTTCTAAAAGGCTTCGAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CGGAAAGGTGCAGCAGAACGCCGAGGCTTACATCGCCGA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	ACTGGCCGAGGATCCGGCCCACAATATTCGAAAT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GAGGCTGGGAAAAATCTGGAGGACAGCAGCAGCCGGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CGCCGCTGGAAGAGTCCTCGACCCCATCGAGTCCCCC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	ATCAGGTTGAGAGTTGCCGTCTTCTTGGCGTAATCA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGGAAAGTTCTACGGTGTGAACATCGAGATCGAAGTC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CCTGCTCCTCTCACTGAAGGCGGATGCGATGCACATT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GACCGCGTATTGCCACTCGTCGTAGCAGAGCGATGT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TTCCAGGGTCCATGTCGAAACCTGCTCAAACCAGGAAA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GATGCGGCCAGGCAGCGACGTTGGCCGAGTTGTGGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGCCTGGCTGACAAGACCTGGCTCGAGAAGAACTA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GAGTTGGTCGGCAAGCCGTTGGCCGCGCGTGAAGACGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AGGAGAAGAGGAACTGACTCAGGCCGGCGTACGTGTG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GTCGCTCCAGGGTGACCGCTACTTGGTTCAGGGCTGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TTCTCGGCATCACCCAGCTTGGCATGCCAAGCGCC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CGGGGACTCGATCCCCGAGCTGACCAAGCGGGTGCA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	ACAGACACCTCCGGGACAGGTTTGCGGGGCTTGTG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GCCGGAGTCGAGGTTGGCACGGATCGGGATGGTCAA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGCGATTATCCTGTTAACAAGATCTGGAGATTTAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CAAGACGACGGCTATAACGTCGTTATAGGGTTAAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TGTCGTCAGGCTGTACTACTGTCACGGCCTGACCAT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GTCAGCGAGCGACCAGTGCTTCGCGTGACAGGCCGATC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GATTCGGAGCAGCGTGCGGTTGCAGCCTGCCGTAATG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CGACCAGGCCGATGCCAACCCGGAGCTCAACTGAT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TTTCGTCCTCGATCTCGGCGAACTCGTGCGTTCTCA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGCGATATCGCCCTTCGCACGCTGGTCGAAGTCGAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGCGATCCCGAGCCGCAAGGGACCGGTCCAGGCCTGG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGGATTGCAAGTAGCTATCACCTGGTCCCGAGGATCTT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC

>NC_019892|15|3|5278274-5282042|CRT
CCTCCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTTGGAGTTGAGCCGACCGACCGGGGCGAGAATGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAT	GTTCACGGCTTGGGCTCCTGGCCAGCGTACGTGATCGT
GCTTCAATGGGGCCACGGCTCGGAGGCCGAGGAAGAC	GGTGGGCATCGACACCAACGATCCCGACTTGCACAA
GCTTCAATGGGGTCACGGCTCGGAGGCCGTGGAAGAC	GACGTCACCGCTGCTGCGGGCAAGAAACTCTACTG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AGAGTAATGCATGGCCTGTAAAGTTGGCATGTCGAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TGACCGAGAATCTGCGGATCTCCGGAAATATCCTCAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GTCTGCACAGGCATCCGAAAAGCTCAGCAACAAAG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GCTCAACGTTGCGTCCTGGCCGAGTCGGAATAGAGT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CAGCCTCGCGGAGGAGCCGGAAGAGGCCGCTCAATT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AGGACCCGAAATGGACCCTCGATCCGGCAAACAA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GTCACACCTCGGTGGACGGAGTAATCCCCGGCTGGGTT
GCTTCAATGGGGTCACGGCCCGGAGGCCGTGGAAGAC	CTTTTATGCTCGCGTGGCCTGGTTGGTTGTCGTCAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GCTCCTGCCGTGACATCCCTGAAAAAGGCTACGCAA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TCACTTGGACGATTTCAAAAAGGCCCTCGGGATAGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AAGCTCCGACGCAATCCACTGTCCGCTGGTGTGGAG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GCCGTTTCGGCTCCAAACAACGGTTTCGTATACC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	ACGGCGTCACAAACGCGGCAACAACCACATTTTGCACAG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CACGCCATCCCTTTGCGGGTCAGAGTGTCAGTGGAGCG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CGAGACCTGGCCGTCCAGATCGACCGGCGTGACTT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AACAATTCGCCGGACCACAACCCGGGGATCCTCGA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TCGCGTCGGGCGCGGCTGTATATACCGCATGGAACG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AAGCTCAAGCCGGCTACCTCAACGGACGCACAAT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CCGATCTGGAGAAGAGAGTTCTAAAAGGCTTCGAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CGGAAAGGTGCAGCAGAACGCCGAGGCTTACATCGCCGA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	ACTGGCCGAGGATCCGGCCCACAATATTCGAAAT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GAGGCTGGGAAAAATCTGGAGGACAGCAGCAGCCGGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CGCCGCTGGAAGAGTCCTCGACCCCATCGAGTCCCCC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	ATCAGGTTGAGAGTTGCCGTCTTCTTGGCGTAATCA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGGAAAGTTCTACGGTGTGAACATCGAGATCGAAGTC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CCTGCTCCTCTCACTGAAGGCGGATGCGATGCACATT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GACCGCGTATTGCCACTCGTCGTAGCAGAGCGATGT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TTCCAGGGTCCATGTCGAAACCTGCTCAAACCAGGAAA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GATGCGGCCAGGCAGCGACGTTGGCCGAGTTGTGGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGCCTGGCTGACAAGACCTGGCTCGAGAAGAACTA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GAGTTGGTCGGCAAGCCGTTGGCCGCGCGTGAAGACGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	AGGAGAAGAGGAACTGACTCAGGCCGGCGTACGTGTG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GTCGCTCCAGGGTGACCGCTACTTGGTTCAGGGCTGC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TTCTCGGCATCACCCAGCTTGGCATGCCAAGCGCC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CGGGGACTCGATCCCCGAGCTGACCAAGCGGGTGCA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	ACAGACACCTCCGGGACAGGTTTGCGGGGCTTGTG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GCCGGAGTCGAGGTTGGCACGGATCGGGATGGTCAA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGCGATTATCCTGTTAACAAGATCTGGAGATTTAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CAAGACGACGGCTATAACGTCGTTATAGGGTTAAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TGTCGTCAGGCTGTACTACTGTCACGGCCTGACCAT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GTCAGCGAGCGACCAGTGCTTCGCGTGACAGGCCGATC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GATTCGGAGCAGCGTGCGGTTGCAGCCTGCCGTAATG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	CGACCAGGCCGATGCCAACCCGGAGCTCAACTGAT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	TTTCGTCCTCGATCTCGGCGAACTCGTGCGTTCTCA
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGCGATATCGCCCTTCGCACGCTGGTCGAAGTCGAC
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGCGATCCCGAGCCGCAAGGGACCGGTCCAGGCCTGG
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC	GGGATTGCAAGTAGCTATCACCTGGTCCCGAGGATCTT
GCTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC

>NC_019892|15|5|5278275-5282042|PILER-CR
CTCCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACT	TTGGAGTTGAGCCGACCGACCGGGGCGAGAATGCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGATG	TTCACGGCTTGGGCTCCTGGCCAGCGTACGTGATCGTG
CTTCAATGGGGCCACGGCTCGGAGGCCGAGGAAGACG	GTGGGCATCGACACCAACGATCCCGACTTGCACAAG
CTTCAATGGGGTCACGGCTCGGAGGCCGTGGAAGACG	ACGTCACCGCTGCTGCGGGCAAGAAACTCTACTGG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACA	GAGTAATGCATGGCCTGTAAAGTTGGCATGTCGACG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACT	GACCGAGAATCTGCGGATCTCCGGAAATATCCTCACG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	TCTGCACAGGCATCCGAAAAGCTCAGCAACAAAGG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	CTCAACGTTGCGTCCTGGCCGAGTCGGAATAGAGTG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACC	AGCCTCGCGGAGGAGCCGGAAGAGGCCGCTCAATTG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACA	GGACCCGAAATGGACCCTCGATCCGGCAAACAAG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	TCACACCTCGGTGGACGGAGTAATCCCCGGCTGGGTTG
CTTCAATGGGGTCACGGCCCGGAGGCCGTGGAAGACC	TTTTATGCTCGCGTGGCCTGGTTGGTTGTCGTCACG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	CTCCTGCCGTGACATCCCTGAAAAAGGCTACGCAAG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACT	CACTTGGACGATTTCAAAAAGGCCCTCGGGATAGCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACA	AGCTCCGACGCAATCCACTGTCCGCTGGTGTGGAGG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	CCGTTTCGGCTCCAAACAACGGTTTCGTATACCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACA	CGGCGTCACAAACGCGGCAACAACCACATTTTGCACAGG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACC	ACGCCATCCCTTTGCGGGTCAGAGTGTCAGTGGAGCGG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACC	GAGACCTGGCCGTCCAGATCGACCGGCGTGACTTG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACA	ACAATTCGCCGGACCACAACCCGGGGATCCTCGAG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACT	CGCGTCGGGCGCGGCTGTATATACCGCATGGAACGG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACA	AGCTCAAGCCGGCTACCTCAACGGACGCACAATG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACC	CGATCTGGAGAAGAGAGTTCTAAAAGGCTTCGACG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACC	GGAAAGGTGCAGCAGAACGCCGAGGCTTACATCGCCGAG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACA	CTGGCCGAGGATCCGGCCCACAATATTCGAAATG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	AGGCTGGGAAAAATCTGGAGGACAGCAGCAGCCGGCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACC	GCCGCTGGAAGAGTCCTCGACCCCATCGAGTCCCCCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACA	TCAGGTTGAGAGTTGCCGTCTTCTTGGCGTAATCAG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	GGAAAGTTCTACGGTGTGAACATCGAGATCGAAGTCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACC	CTGCTCCTCTCACTGAAGGCGGATGCGATGCACATTG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	ACCGCGTATTGCCACTCGTCGTAGCAGAGCGATGTG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACT	TCCAGGGTCCATGTCGAAACCTGCTCAAACCAGGAAAG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	ATGCGGCCAGGCAGCGACGTTGGCCGAGTTGTGGCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	GCCTGGCTGACAAGACCTGGCTCGAGAAGAACTAG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	AGTTGGTCGGCAAGCCGTTGGCCGCGCGTGAAGACGCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACA	GGAGAAGAGGAACTGACTCAGGCCGGCGTACGTGTGG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	TCGCTCCAGGGTGACCGCTACTTGGTTCAGGGCTGCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACT	TCTCGGCATCACCCAGCTTGGCATGCCAAGCGCCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACC	GGGGACTCGATCCCCGAGCTGACCAAGCGGGTGCAG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACA	CAGACACCTCCGGGACAGGTTTGCGGGGCTTGTGG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	CCGGAGTCGAGGTTGGCACGGATCGGGATGGTCAAG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	GCGATTATCCTGTTAACAAGATCTGGAGATTTACG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACC	AAGACGACGGCTATAACGTCGTTATAGGGTTAACG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACT	GTCGTCAGGCTGTACTACTGTCACGGCCTGACCATG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	TCAGCGAGCGACCAGTGCTTCGCGTGACAGGCCGATCG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	ATTCGGAGCAGCGTGCGGTTGCAGCCTGCCGTAATGG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACC	GACCAGGCCGATGCCAACCCGGAGCTCAACTGATG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACT	TTCGTCCTCGATCTCGGCGAACTCGTGCGTTCTCAG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	GCGATATCGCCCTTCGCACGCTGGTCGAAGTCGACG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	GCGATCCCGAGCCGCAAGGGACCGGTCCAGGCCTGGG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGACG	GGATTGCAAGTAGCTATCACCTGGTCCCGAGGATCTTG
CTTCAATGGGGCCACGGCCCGGAGGCCGTGGAAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015247579.1\|5270859_5271645_+\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276
NC_019892.1\|WP_015247583.1\|5277413_5278121_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_157579444.1\|5271785_5273372_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247582.1\|5277070_5277364_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020467532.1\|5269674_5270142_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247587.1\|5286072_5286360_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247585.1\|5283387_5284611_-\|EstA-family-serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_019892.1\|WP_026012191.1\|5299732_5300002_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270916
NC_019892.1\|WP_015247586.1\|5284717_5285713_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_019892.1\|WP_015247575.1\|5267366_5267702_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020467538.1\|5300030_5300663_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270916
NC_019892.1\|WP_015247594.1\|5303497_5304139_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247577.1\|5268884_5269370_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_019892.1\|WP_020467535.1\|5282619_5283132_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|224168
NC_019892.1\|WP_015247593.1\|5302912_5303371_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247581.1\|5273805_5274717_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247576.1\|5268136_5268556_+\|protease-inhibitor-I42-family-protein	unknown	unknown	gnl\|CDD\|378179
NC_019892.1\|WP_015247588.1\|5286834_5287926_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_019892.1\|WP_015247595.1\|5304903_5305239_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015244181.1\|5275064_5276450_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|373239

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247579.1\|5270859_5271645_+\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	2.04255e-31
NC_019892.1\|WP_020467538.1\|5300030_5300663_+\|hypothetical-protein	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.14754e-26
NC_019892.1\|WP_026012191.1\|5299732_5300002_+\|hypothetical-protein	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	9.40595e-08
NC_019892.1\|WP_015247577.1\|5268884_5269370_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.06349e-13
NC_019892.1\|WP_020467535.1\|5282619_5283132_-\|N-acetyltransferase	gnl\|CDD\|224168	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane].	1.11547e-39
NC_019892.1\|WP_015247585.1\|5283387_5284611_-\|EstA-family-serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.96629e-57
NC_019892.1\|WP_015247586.1\|5284717_5285713_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.76099e-17
NC_019892.1\|WP_015247576.1\|5268136_5268556_+\|protease-inhibitor-I42-family-protein	gnl\|CDD\|378179	pfam09394, Inhibitor_I42, Chagasin family peptidase inhibitor I42. Chagasin is a cysteine peptidase inhibitor which forms a beta barrel structure.	0.000470228
NC_019892.1\|WP_015247588.1\|5286834_5287926_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.27315e-60
NC_019892.1\|WP_015244181.1\|5275064_5276450_+\|IS4-family-transposase	gnl\|CDD\|373239	pfam14706, Tnp_DNA_bind, Transposase DNA-binding. This domain occurs at the C-terminus of transposases including E. coli tnpA. TnpA encodes a transposase and an inhibitor protein, the inhibitor only differs from the transposase by the absence of the N-terminal 55 amino acids, which includes most of this domain. This domain consists of alpha helices and turns, and functions as a DNA-binding domain.	3.82088e-18

>NC_019892.1|WP_015247583.1|5277413_5278121_-|hypothetical-protein
MIARFAVVILASQWIACLCASAQSHLEPENGILNATDSTWNSSKRIREVLLKEATYYHLARMVCLPSFDEPEWVVTVVRQDGEELDAPHTYFVEYVGAETKLFLAKGAQDVQVKRSRAPLDRSTAESLNKTWRRMLRSTRYPKDPRLGADGVNYHFSRFVPLIDRGRNDPLAGWEQGKIWTPDEDSLCGELVAIGEELKRYAVALPADRDRIHDRIRAKEHQLKAKLNRESKTAP
>NC_019892.1|WP_015247582.1|5277070_5277364_+|hypothetical-protein
MAFWPIVGWSSVCLGCVAALYGLHRLGLRLEEQGYIYYWYKKPSGSAAGCFVALQRAVEPQVQHVEQARAEQNRDGDDESAGRRRAQEAEEGQEPMN
>NC_019892.1|WP_015244181.1|5275064_5276450_+|IS4-family-transposase
MSPTLTDPEAWAQANFAGADLGDKRRETRLIRLATQIAVDSSASLPKATGNWDDLRAAYRLLDSSAVNFRAIAEPHWRSIRETSPEMALILDDTTEIDFGCTRQIQGVGPVGTGTGQGFMIHSGLMVSHKDEVVYGLAGQILFHRKPVPKGESRTQRRKRDRESEVWGKLIELIGSPPQNTRWVHVMDRGSDDFEVYCRAQRQGVDWVGRVKSLHRRVQGADGLERPLQEELESVPQAGCFTLKLRSRPGLPARTAKLTVTFVRATMLVPRQPADSLKGLDPQPIAQYVVCVREVDPPASVKEPIEWVLYTSLEVACLEDALRIISYYEKRWLIEEWHKALKSGCSAADHQLKASHRLEALTGLLSVVAVRLLQLKGIARSEPERPAIEAAPPKYVAVLRAFRRTTEALPWGTYQFFRELAKLGGFLGRKGDGEPGWQTIWRGWMKLQAMVQGAELDLRLE
>NC_019892.1|WP_015247581.1|5273805_5274717_+|hypothetical-protein
MGGNGVRVPHFVIALAYLLSSLAIPSVSYAADLKPYPLPPAARADIEKLAASSNVLILGETHGTQEVPELTASLLEPLAKLDYHILAIEVPNKEQASLLAWAHGKTERVPDFFANPSGDGRGNAQLLSLVRIAVSPPFRWQVICFDDTESMLEQQRLILMQKKPTGGAEAPQLTAEDGIALWRARDAAMAANLLRETKSLKTTSKILAVCGNLHARVTNDMQDPDLSKLWPSFAGMLKQGQPAWRVSSVNIEFYRGAFFNEGKVRTIQGRPLEHAVVRSADQTGWNLELSLPEATPATFHFSK
>NC_019892.1|WP_157579444.1|5271785_5273372_+|hypothetical-protein
MMRNRLGVLGLVAVLFAGTASGQNVPKPSTSDSVNAEKETRYLAFQIFTHYSSDPKVAVLLNSGSREPVLPGTAALRNWVEDIKRRIGTVGDERTRLAVMLGPLCFEQDDAEVTRFIELAFRLALETDVAVGFHIDDSMFWAKRKDLWSDPKNVEALDWDGTPCTGRRLNWGKEPTAAPPQMCFNSKAIQREVQQRSALLGKAIQAGVKSLQEHKKPELFAGVIAGWETMIGQDFKTGKYLGYRALMNRGFSRERPPQDMNLEREKVVQEFIEHWTKGLAEAGVSPQKIYSHTAFLSRRAFNLGDDKAITYMKRDKESAYSQHNHFAPPSMAFGENHRPGFSTYPQPGLFEDIYEQMARHKQVGWASSEGTNMQPSSGPGQTGMDMETYLAKMFNHGATLVNLFSWGVGGDAMKTMGFRVVTEGEEAIRAYRKFLKGDALVEAKTEESLMERLPPKIHKIQKELPGWIEKAEVDSKKKAMSLMKQLQEQMKAKNFEEVEETANSLLKMMKGASAPAAAQDTPKEAGRG
>NC_019892.1|WP_015247579.1|5270859_5271645_+|pentapeptide-repeat-containing-protein
MNRKCALKLLRGGPEGIQEWNRRVGELTETLDLRGADLQGQDLREAFLRGPLRSGIKIDLAEADLRAADLRKANLSTSNLEKANLAGAILNRAAFRYTWLDGADLTGVDLRKTSMSDTDLRRVKLRNALLTGARFKGTCLIGADLAETDLSGTHFGNTEFGDADLRGVNLRHVDLFGSRFKEADLRGADLTGANVKNCHFDDTKLEGTIFTDAAFEWTIVSGVDLRKAIGLTLEQLNSSKWNKKTRFPAYLPSRPQKGQWI
>NC_019892.1|WP_020467532.1|5269674_5270142_-|hypothetical-protein
MPKALSAFGMAWGPTMADESQRKPVKIGVKEGGGPPPGYKWNVEILEQAFAEAMGFLNADQYCHLASQFRELAGQDEASQSQTVDVRPIEDFYELRDKGGILRRMNTRIFFFIHKKMRTIVILGAIKKENDGATPMGDKITMRRRKRLYLQADSR
>NC_019892.1|WP_015247577.1|5268884_5269370_-|helix-turn-helix-transcriptional-regulator
MLTEKIGETYSELPEAVKPALLALSILIDRIGSLPKADRDDLFELLQEWQKAETPEDQRSVQRAMEEILAQVPVTTRPLPLNDSAAMSPSSKTWAEHVGKAIRKLRCDLGWTQKQLAEKAGLPQSHVSRLENAEYTATNLTLTKIATALGVEVRAMDPCAD
>NC_019892.1|WP_015247576.1|5268136_5268556_+|protease-inhibitor-I42-family-protein
MSRQHGILGALATACLLATSWGIAYGAEHELGRLERIVKSGEYTAASGDLVEISVPSNPSTGPSNPAAKLKVSVHGDHLKKVGVYFAPPAKPLPGAPGEIRAYLTAHGNGTSKVTVTPISGSGQEGTPLEITLKVAKGE
>NC_019892.1|WP_015247575.1|5267366_5267702_-|hypothetical-protein
MPRFRFRMRGILVAVAVVGILLGLHQWMSRRARRFHAISESHRSRLSLVISGPVTSEGDFLGVPSVLDRDLKTVSRHRARKELWHYTMSVRYKRAAERPWLPVPPDPPEPY
>NC_019892.1|WP_020467535.1|5282619_5283132_-|N-acetyltransferase
MFIRDATEADLPAIVDIYNQSIPAGWSTADTQPITVADRLDWFRKFDPARRPIWVAEVDGQIAATAYLSSFYGGRAAYDATAEVSLYIATAFQRRGIGRQFKQWVIAECPRLGVTTLLSMHFDHNEATRRINESLGFQPLGHLTEIALVQGTKRGLVISALRIPPKPETP
>NC_019892.1|WP_015247585.1|5283387_5284611_-|EstA-family-serine-hydrolase
MSNVDGLVEDGWGQVADTFRANFKEGKDLGAACCVYVDGRAVVDLWGGLADREKNRPWERDTVALVASTTKGATAICAHLLVQRGQLDLDAPVIRYWPEFGAAGKEKIPVRWLLSHQAGLPYVDTPVTFEEACAWDPLIRALEVQKPLWTPGTEHLYHAMTYGFLVGEVIRRITGRSPGTFFAEEIAQPLGLSAWIGLPEEVEPRIARIEAAPFPYKSMEDLAPDFAKLMGLDLAVAVTLVKDVYGPGSAFMKAGAVGDVTGENVLSRAYRAAEFPGANMFANAHSIARMYAATVSDVDGIRLLQPDTVAAMTVAQTDRTRMHGAPPELLPATKNLFNMSLGFVRSAPPVMSMFGPASFGHPGSGGSLGAADPESRVGFGYVPNLWAATMVDPRAIELTSAVAKCLG
>NC_019892.1|WP_015247586.1|5284717_5285713_-|alpha/beta-hydrolase
MSQATAPPHRFSISAGRDDRPANTLGRARGRRFRPLAAFSLLTALTALSCTRAEDPAATAPNRQSVDVGGYKLTLLTRGQGTPTVVIEPGMGLAAVESDEWTVVCEEIAKTNRVCLYDRAGLGTSDPAPTRPRTSQDIARDLHALLINAKVPGPYVLVGHSIGGLNVRVFADLYPDEVAGVVLVDVTHPDQESKWLASLPAESPEELPALKKSRELLTSRLERGSDNPDGMDVVTSREQVRSTSTLGDKPLAVLTHSPDWKMVPDLPDAILKPLEQISQDLQASLPALSTNSSHKVAKKAGHAIHLDEPSLVIEAVREVLEKANGNTAKLR
>NC_019892.1|WP_015247587.1|5286072_5286360_+|hypothetical-protein
MTDDEPSSPISRGPFFSNEGPDDGLVMLGKAPFLEVLDGARKVIGTAWPVGAIPSRKGMAQLWFLEVGQIGLPGVYVCRRKIFVRIMDTAEDSPD
>NC_019892.1|WP_015247588.1|5286834_5287926_+|serine-hydrolase
MTRPIAFLLLFATTPAFAQAPPYARADKVDAVAGAEVAKQKLVGLAVVVIDEGRIAWSKGYGYADQEKAVPVDPAGTQFRWASISKPVTAVAALQLAESGRLDLDADVRTYVPEFPDKGEKITPRNLLCHQGGIVHYTNGKVVRSEKEYADPHPFADVVVAMDMFKESPLVNRPGEKYAYSTHGFILLSAVVERAGKQRFADQVRARVAEPLGMTNFRPDYQWEDIPNRAIGYTRTDGVIARRDEDHDVSWKLGGGGFTSSATDLARFGVGLLQRKLVSEETEKLMWTVNKPADPQGAKPYGLGFFVLDLPGGRTIVGHDGSQEKTRTALMLDPKGQRGIALMTNSEWCDAAQLALTLMDELK
>NC_019892.1|WP_026012191.1|5299732_5300002_+|hypothetical-protein
MRNISALLPQIPGFQVERELGRGGMGVAYLARQESRNRSVVLKFIGGAARLTLLNWHASALRLGPSLVLLIRTLSEFTMSAFVSQAACL
>NC_019892.1|WP_020467538.1|5300030_5300663_+|hypothetical-protein
MIAPAIRSLWEEATHEHRSPDESHVAVSQYVAEWLEQVRQPLPATAPPLENLTRFGAILGTPEYMAPEQMCGNTDSTGPRADLYALGVTMYQMLVGHRPNAVIQYEAGVHYPLPSRTRVSSELEAICNQCLRYRAEDRYPHVGELVADLDRFLGGYAVVAALPECAGAVGPNRSAKTETAPGTTVAQSHPQESTRSWWPLSRRKVSRKES
>NC_019892.1|WP_015247593.1|5302912_5303371_+|hypothetical-protein
MEAKEPLPGPGCFQWNRGGWFGGQLGSTVWMLVGGVVLVPYALDVACVWLACFAVANAIGAWLWRGRDRLPPYPALQALLATCGVSSLVALAALHILRPGLRITRPPGIWLADEPQYLPWVLVLFLAVMTSCSLRERSARRQVLRSKGPSTP
>NC_019892.1|WP_015247594.1|5303497_5304139_+|hypothetical-protein
MFVERASIAQVMAFVALAAVNLGVFRALPLEVVRFPTLWVFLGAIDVVIFRKLICVRSLRAFHYTFLIVFVLAWIVMANLVVTARFHPLGLLVQWYQQITTDKINVVSLDSFDFYELWMTCFLSFALAVAIGLVAAWFESRRNWDIAACLRGALAGFGIANLLAVIDGAVWGWGVVSPVRMVGRLILVGVCVILGGVVGLSKLKSNTPGRRVP
>NC_019892.1|WP_015247595.1|5304903_5305239_-|hypothetical-protein
MCPNNLVLDPENSANVTIDEDPERWPNDQQASADPSQIATTQVAMSWYLTVAEQLAMDRAIPSDAATEKAFGDVDQKTKRVERLNALKNEAFKTVWAPDARPTCTSSTSEP

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Crispr_ID: NC_019892_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_16

5291494-5297044

Orphan

Consensus_repeat	Method
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CRT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CRISPRCasFinder
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	PILER-CR

75 spacers

The CRISPR arrays of NC_019892_16

>merge|NC_019892|16|5291494-5297044|CRT,CRISPRCasFinder,PILER-CR
TTTTTATGTGCGTATTAGATCGGAGGCCGTGGAAGACTCCGACGGCCGCCACGCACGTGAAGCCTTGGATCTACGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTCCGCAAAGGAGGCTCTTGTAATGGCTCGAATATTGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCTCGGGGCTGACGCGATTGCGATCAGCGAGGCGACAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCTGCTTCGATCCTGGGCACTTACCCTGCGGCCCTCCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCCAACAGCGCCGTCGACCCGAACCGACTTCACCGGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGATATCATTATGTAGTTGTAATAACGCAATAAGATAAGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTGTCGAAATCAGGTCGACATGGCGAATCCGGGTGTAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACATTCGCTGATGGCTCAACAGCCTATACGGTGAATGGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACATGGTGTCCTGGGTTCACTCGATCAAGGAGGGCCTCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGCCGGCACGGCCGCAGTGTCAACAAGCAAGCTGGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCCCAGTGCCCTCGGGGATCTTCTCATTGACCCCAAGTTCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTCAGTTTAAACAAGACCTCATCACCTGTGATGATGAGTCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCAATGGATCCCAATCCCCGGCCGATCGTCGAGCCGTCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGTGCCACGGGGCCAAACGAAGAGGGCAGAAGAGATTCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTCGAACTCGCCGCGCAGCGCCGAGGAGATCGCCGTTCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGTGTCGCCCCGAAACATCGGGGAAGCTGTTGCGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTCGAGAAGACGATCGAATGCTACGTCAACGGCGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGATCGACCTGGATTTCACTGCTTCGGCATTGATCGTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTTATCGTCCAGGAAGCGTTCTCGGCAATGGAGTGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGATCGAGACCAGGGCACCACGCGACTTCGGACCAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACAGCGGCTTGCGGAATTCGCACACTCTCGCAATCACCGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCGCCCAGGGGCACGGTGACCGGACCAGGCCAAGCTTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCCCGACGTGCGTGAGTTCGCTCACGCCTGAGATCCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTCCTACAGTGGCGCGATTACCGTCACTGACTTCCCCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTCACTTGGGAGAGAGAGGACGGGGCCGAAATCTCGATCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACAGTATCCAGCCTCGCGTTAGAGCGACGGCAGAGAAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCAAGGGCTCAAATCAGGCTAAATTTGACTGCCTGCGGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCCTGCTCTCCGCGATCGCTGGCGCCACCAGCGAGGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGATAACAAGTGCGGGCCGAGTGACTTTCCGAGTGACGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCCGCGAGCTGGCTCGAACGCGGGCGGCCATGGAAGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCTGCCGTCCGTGGTCGTCGACGCCGGCCAGTTCGGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGGACGATCGAGGCAGTCGCGAAGCGGCTGTGATCGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTGGGGGATGGATGTTAACAATCAAGTAATCATGGGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGAGAAACCCCCAAGGATTCTTAGAATGTTAAAATGTAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGAAAAACCCTAGGCGAACAGGTAGCTGCAGCGCTCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTGATCCGTCCAAGGCCAAGCAGATGCAGAGCTATGCCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACAAGGACTAGCCCGGTCTTACATCGACAAGGGGCAAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGATCCGAGATGGAATTCGGTGACTGCGGCTGCGGAATGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACATTGCGATTAGAGCCGCGCTTGACGGCCGCGAACTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACAACCTTCCGGTCGTTGAGAATTTCGGAGTACAACTTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTTGCCGACACCTCCGAGGGCTTTAAGAAACTCCTCGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCTGGATGCCGACGCCGGGCGAACGGCACACCGACTAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGACCCCGAGATCGGTCGGTACTACGCGGTCAGCTATGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGCCGATCGTGCTGGAGTGTTTGCGCGAACAGGAAGTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACACAGCCCCAATCCAAATCGCGGTCCCCAAGGGATCAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGCGGGAGTGACGTCGCTGTGTGGGTCGAGGACGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTGGCCGGTCGAAACTCGACGCCCACAGACTCTCTACCGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTGAATCGCACACTCGTCCCGACGGCCCAGATCGTGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCTCGAGGCGGCCCGCGTGCCGATCTCCGCTGTCCGGATGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTCAACTAATTTGACTACAAATTTATGGGGAATTCGCAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGGGCTGATTCGTCGGGTACGAAGTAGGGGACCGACGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCCGATTACCGGTCAAAAGACCAGGCAGGGCACCGGAAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACATCGGACCCGGTATACACGTTGACCATGTGCGGTGGGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGGAACAACCCGGCCCACGGCCAGAACGGCAAGCCCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTGTGACCACGGAACGGAGTCGTTCGGGACGGGCGAGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGCCGATCGTGCTGGAGTGTTTGCGCGAACAGGAAGTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACACAGCCCCAATCCAAATCGCGGTCCCCAAGGGATCAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTGATGAGCCGTCGTAAGACATGATCGCCCGATTTAGTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTACTCTTGCTGAAATCGCCCGGCTTGGGCAGGTCTCTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTCGCGGCCGGGATGCACGTCGCCGCCGGGATGCCGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCGAAGGCGTCATGAGCAACGGACTGGCGACACGAGAGACGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCCCGCAGTACTTGCGGCAAGGGCGAGGTCGGCCTTTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACACCCCCGAGGCCGTGGTCGGGGTGTTCGACACTGAGGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGACTGGGACGAAGGTGACGACACTTGCACGAGCAAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTCGCCTTGCCGGCCGCTCCTGATCCTGCGCCTCCCGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTGTTGGTTCCCGAAGGGGTTCCGGCGTCCCCTTCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCCGGGTGGGCCCGGAAGGGAACAAGAGAACAGCAACCCCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTCACCGGATGAGGTCGCTCGGAATCGGCGGCCACATGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCCTCGGCGAGCAGTTCCTGCCGGGCAGCACCTTCGGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCCAGGTCGCGGAGGGGCGCATTGTGGTGACGACCGATGGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCCAACGGCTATGTGGCCGGTTCGACATACCAGGTTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGGGACAGTAGTGGCAGGACCGGCTTTCCCCAGGGTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGAGCGGGCGAATCTATTTCCCTAACAAGGTAGCGAAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGGACGCCACCTGGGACGCCACCGAGGCCGCAAAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCGGCGTTCTCGATGGTTTGCAGCCCAGACGCCACGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC

>NC_019892|16|4|5291494-5297044|CRT
TTTTTATGTGCGTATTAGATCGGAGGCCGTGGAAGAC	TCCGACGGCCGCCACGCACGTGAAGCCTTGGATCTAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCCGCAAAGGAGGCTCTTGTAATGGCTCGAATATTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTCGGGGCTGACGCGATTGCGATCAGCGAGGCGACA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGCTTCGATCCTGGGCACTTACCCTGCGGCCCTCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCAACAGCGCCGTCGACCCGAACCGACTTCACCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAT	ATCATTATGTAGTTGTAATAACGCAATAAGATAAGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGTCGAAATCAGGTCGACATGGCGAATCCGGGTGTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATTCGCTGATGGCTCAACAGCCTATACGGTGAATGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGGTGTCCTGGGTTCACTCGATCAAGGAGGGCCTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGCCGGCACGGCCGCAGTGTCAACAAGCAAGCTGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCCAGTGCCCTCGGGGATCTTCTCATTGACCCCAAGT
TCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCAGTTTAAACAAGACCTCATCACCTGTGATGATGAG
TCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCAATGGATCCCAATCCCCGGCCGATCGTCGAGCCG
TCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGTGCCACGGGGCCAAACGAAGAGGGCAGAAGAGAT
TCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCGAACTCGCCGCGCAGCGCCGAGGAGATCGCCGT
TCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGTGTCGCCCCGAAACATCGGGGAAGCTGTTGCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCGAGAAGACGATCGAATGCTACGTCAACGGCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATCGACCTGGATTTCACTGCTTCGGCATTGATCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTTATCGTCCAGGAAGCGTTCTCGGCAATGGAGTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGATCGAGACCAGGGCACCACGCGACTTCGGACCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AGCGGCTTGCGGAATTCGCACACTCTCGCAATCACCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGCCCAGGGGCACGGTGACCGGACCAGGCCAAGCTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCCGACGTGCGTGAGTTCGCTCACGCCTGAGATCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCCTACAGTGGCGCGATTACCGTCACTGACTTCCCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCACTTGGGAGAGAGAGGACGGGGCCGAAATCTCGATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AGTATCCAGCCTCGCGTTAGAGCGACGGCAGAGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGGGCTCAAATCAGGCTAAATTTGACTGCCTGCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCTGCTCTCCGCGATCGCTGGCGCCACCAGCGAGGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATAACAAGTGCGGGCCGAGTGACTTTCCGAGTGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGCGAGCTGGCTCGAACGCGGGCGGCCATGGAAGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGCCGTCCGTGGTCGTCGACGCCGGCCAGTTCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGGACGATCGAGGCAGTCGCGAAGCGGCTGTGATCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGGGGATGGATGTTAACAATCAAGTAATCATGGGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGAAACCCCCAAGGATTCTTAGAATGTTAAAATGTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGAAAAACCCTAGGCGAACAGGTAGCTGCAGCGCTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGATCCGTCCAAGGCCAAGCAGATGCAGAGCTATGCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAGGACTAGCCCGGTCTTACATCGACAAGGGGCAAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATCCGAGATGGAATTCGGTGACTGCGGCTGCGGAAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATTGCGATTAGAGCCGCGCTTGACGGCCGCGAACT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AACCTTCCGGTCGTTGAGAATTTCGGAGTACAACTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTTGCCGACACCTCCGAGGGCTTTAAGAAACTCCTCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGGATGCCGACGCCGGGCGAACGGCACACCGACTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GACCCCGAGATCGGTCGGTACTACGCGGTCAGCTAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGATCGTGCTGGAGTGTTTGCGCGAACAGGAAGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCCCCAATCCAAATCGCGGTCCCCAAGGGATCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGCGGGAGTGACGTCGCTGTGTGGGTCGAGGACGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGGCCGGTCGAAACTCGACGCCCACAGACTCTCTACCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTGAATCGCACACTCGTCCCGACGGCCCAGATCGTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTCGAGGCGGCCCGCGTGCCGATCTCCGCTGTCCGGATG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCAACTAATTTGACTACAAATTTATGGGGAATTCGCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGGGCTGATTCGTCGGGTACGAAGTAGGGGACCGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGATTACCGGTCAAAAGACCAGGCAGGGCACCGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATCGGACCCGGTATACACGTTGACCATGTGCGGTGGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGAACAACCCGGCCCACGGCCAGAACGGCAAGCCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTGTGACCACGGAACGGAGTCGTTCGGGACGGGCGAGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGATCGTGCTGGAGTGTTTGCGCGAACAGGAAGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCCCCAATCCAAATCGCGGTCCCCAAGGGATCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGATGAGCCGTCGTAAGACATGATCGCCCGATTTAGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TACTCTTGCTGAAATCGCCCGGCTTGGGCAGGTCTCT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCGCGGCCGGGATGCACGTCGCCGCCGGGATGCCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAAGGCGTCATGAGCAACGGACTGGCGACACGAGAGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCCGCAGTACTTGCGGCAAGGGCGAGGTCGGCCTTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACCCCCGAGGCCGTGGTCGGGGTGTTCGACACTGAGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGACTGGGACGAAGGTGACGACACTTGCACGAGCAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCGCCTTGCCGGCCGCTCCTGATCCTGCGCCTCCCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTGTTGGTTCCCGAAGGGGTTCCGGCGTCCCCTTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGGGTGGGCCCGGAAGGGAACAAGAGAACAGCAACCCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCACCGGATGAGGTCGCTCGGAATCGGCGGCCACAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCTCGGCGAGCAGTTCCTGCCGGGCAGCACCTTCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCAGGTCGCGGAGGGGCGCATTGTGGTGACGACCGATGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCAACGGCTATGTGGCCGGTTCGACATACCAGGTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGGACAGTAGTGGCAGGACCGGCTTTCCCCAGGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGCGGGCGAATCTATTTCCCTAACAAGGTAGCGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGGACGCCACCTGGGACGCCACCGAGGCCGCAAAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGGCGTTCTCGATGGTTTGCAGCCCAGACGCCAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC

>NC_019892|16|15|5291568-5297044|CRISPRCasFinder
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCCGCAAAGGAGGCTCTTGTAATGGCTCGAATATTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTCGGGGCTGACGCGATTGCGATCAGCGAGGCGACA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGCTTCGATCCTGGGCACTTACCCTGCGGCCCTCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCAACAGCGCCGTCGACCCGAACCGACTTCACCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAT	ATCATTATGTAGTTGTAATAACGCAATAAGATAAGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGTCGAAATCAGGTCGACATGGCGAATCCGGGTGTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATTCGCTGATGGCTCAACAGCCTATACGGTGAATGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGGTGTCCTGGGTTCACTCGATCAAGGAGGGCCTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGCCGGCACGGCCGCAGTGTCAACAAGCAAGCTGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCCAGTGCCCTCGGGGATCTTCTCATTGACCCCAAGT
TCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCAGTTTAAACAAGACCTCATCACCTGTGATGATGAG
TCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCAATGGATCCCAATCCCCGGCCGATCGTCGAGCCG
TCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGTGCCACGGGGCCAAACGAAGAGGGCAGAAGAGAT
TCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCGAACTCGCCGCGCAGCGCCGAGGAGATCGCCGT
TCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGTGTCGCCCCGAAACATCGGGGAAGCTGTTGCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCGAGAAGACGATCGAATGCTACGTCAACGGCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATCGACCTGGATTTCACTGCTTCGGCATTGATCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTTATCGTCCAGGAAGCGTTCTCGGCAATGGAGTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGATCGAGACCAGGGCACCACGCGACTTCGGACCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AGCGGCTTGCGGAATTCGCACACTCTCGCAATCACCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGCCCAGGGGCACGGTGACCGGACCAGGCCAAGCTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCCGACGTGCGTGAGTTCGCTCACGCCTGAGATCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCCTACAGTGGCGCGATTACCGTCACTGACTTCCCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCACTTGGGAGAGAGAGGACGGGGCCGAAATCTCGATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AGTATCCAGCCTCGCGTTAGAGCGACGGCAGAGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGGGCTCAAATCAGGCTAAATTTGACTGCCTGCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCTGCTCTCCGCGATCGCTGGCGCCACCAGCGAGGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATAACAAGTGCGGGCCGAGTGACTTTCCGAGTGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGCGAGCTGGCTCGAACGCGGGCGGCCATGGAAGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGCCGTCCGTGGTCGTCGACGCCGGCCAGTTCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGGACGATCGAGGCAGTCGCGAAGCGGCTGTGATCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGGGGATGGATGTTAACAATCAAGTAATCATGGGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGAAACCCCCAAGGATTCTTAGAATGTTAAAATGTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGAAAAACCCTAGGCGAACAGGTAGCTGCAGCGCTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGATCCGTCCAAGGCCAAGCAGATGCAGAGCTATGCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAGGACTAGCCCGGTCTTACATCGACAAGGGGCAAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATCCGAGATGGAATTCGGTGACTGCGGCTGCGGAAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATTGCGATTAGAGCCGCGCTTGACGGCCGCGAACT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AACCTTCCGGTCGTTGAGAATTTCGGAGTACAACTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTTGCCGACACCTCCGAGGGCTTTAAGAAACTCCTCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGGATGCCGACGCCGGGCGAACGGCACACCGACTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GACCCCGAGATCGGTCGGTACTACGCGGTCAGCTAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGATCGTGCTGGAGTGTTTGCGCGAACAGGAAGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCCCCAATCCAAATCGCGGTCCCCAAGGGATCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGCGGGAGTGACGTCGCTGTGTGGGTCGAGGACGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGGCCGGTCGAAACTCGACGCCCACAGACTCTCTACCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTGAATCGCACACTCGTCCCGACGGCCCAGATCGTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTCGAGGCGGCCCGCGTGCCGATCTCCGCTGTCCGGATG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCAACTAATTTGACTACAAATTTATGGGGAATTCGCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGGGCTGATTCGTCGGGTACGAAGTAGGGGACCGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGATTACCGGTCAAAAGACCAGGCAGGGCACCGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATCGGACCCGGTATACACGTTGACCATGTGCGGTGGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGAACAACCCGGCCCACGGCCAGAACGGCAAGCCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTGTGACCACGGAACGGAGTCGTTCGGGACGGGCGAGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGATCGTGCTGGAGTGTTTGCGCGAACAGGAAGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCCCCAATCCAAATCGCGGTCCCCAAGGGATCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGATGAGCCGTCGTAAGACATGATCGCCCGATTTAGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TACTCTTGCTGAAATCGCCCGGCTTGGGCAGGTCTCT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCGCGGCCGGGATGCACGTCGCCGCCGGGATGCCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAAGGCGTCATGAGCAACGGACTGGCGACACGAGAGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCCGCAGTACTTGCGGCAAGGGCGAGGTCGGCCTTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACCCCCGAGGCCGTGGTCGGGGTGTTCGACACTGAGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGACTGGGACGAAGGTGACGACACTTGCACGAGCAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCGCCTTGCCGGCCGCTCCTGATCCTGCGCCTCCCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTGTTGGTTCCCGAAGGGGTTCCGGCGTCCCCTTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGGGTGGGCCCGGAAGGGAACAAGAGAACAGCAACCCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCACCGGATGAGGTCGCTCGGAATCGGCGGCCACAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCTCGGCGAGCAGTTCCTGCCGGGCAGCACCTTCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCAGGTCGCGGAGGGGCGCATTGTGGTGACGACCGATGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCAACGGCTATGTGGCCGGTTCGACATACCAGGTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGGACAGTAGTGGCAGGACCGGCTTTCCCCAGGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGCGGGCGAATCTATTTCCCTAACAAGGTAGCGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGGACGCCACCTGGGACGCCACCGAGGCCGCAAAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGGCGTTCTCGATGGTTTGCAGCCCAGACGCCAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC

>NC_019892|16|6|5294349-5297044|PILER-CR
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AACCTTCCGGTCGTTGAGAATTTCGGAGTACAACTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTTGCCGACACCTCCGAGGGCTTTAAGAAACTCCTCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGGATGCCGACGCCGGGCGAACGGCACACCGACTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GACCCCGAGATCGGTCGGTACTACGCGGTCAGCTAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGATCGTGCTGGAGTGTTTGCGCGAACAGGAAGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCCCCAATCCAAATCGCGGTCCCCAAGGGATCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGCGGGAGTGACGTCGCTGTGTGGGTCGAGGACGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGGCCGGTCGAAACTCGACGCCCACAGACTCTCTACCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTGAATCGCACACTCGTCCCGACGGCCCAGATCGTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTCGAGGCGGCCCGCGTGCCGATCTCCGCTGTCCGGATG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCAACTAATTTGACTACAAATTTATGGGGAATTCGCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGGGCTGATTCGTCGGGTACGAAGTAGGGGACCGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGATTACCGGTCAAAAGACCAGGCAGGGCACCGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATCGGACCCGGTATACACGTTGACCATGTGCGGTGGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGAACAACCCGGCCCACGGCCAGAACGGCAAGCCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTGTGACCACGGAACGGAGTCGTTCGGGACGGGCGAGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGATCGTGCTGGAGTGTTTGCGCGAACAGGAAGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCCCCAATCCAAATCGCGGTCCCCAAGGGATCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGATGAGCCGTCGTAAGACATGATCGCCCGATTTAGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TACTCTTGCTGAAATCGCCCGGCTTGGGCAGGTCTCT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCGCGGCCGGGATGCACGTCGCCGCCGGGATGCCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAAGGCGTCATGAGCAACGGACTGGCGACACGAGAGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCCGCAGTACTTGCGGCAAGGGCGAGGTCGGCCTTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACCCCCGAGGCCGTGGTCGGGGTGTTCGACACTGAGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGACTGGGACGAAGGTGACGACACTTGCACGAGCAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCGCCTTGCCGGCCGCTCCTGATCCTGCGCCTCCCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTGTTGGTTCCCGAAGGGGTTCCGGCGTCCCCTTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGGGTGGGCCCGGAAGGGAACAAGAGAACAGCAACCCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCACCGGATGAGGTCGCTCGGAATCGGCGGCCACAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCTCGGCGAGCAGTTCCTGCCGGGCAGCACCTTCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCAGGTCGCGGAGGGGCGCATTGTGGTGACGACCGATGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCAACGGCTATGTGGCCGGTTCGACATACCAGGTT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGGACAGTAGTGGCAGGACCGGCTTTCCCCAGGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGCGGGCGAATCTATTTCCCTAACAAGGTAGCGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGGACGCCACCTGGGACGCCACCGAGGCCGCAAAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGGCGTTCTCGATGGTTTGCAGCCCAGACGCCAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015247587.1\|5286072_5286360_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247583.1\|5277413_5278121_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247600.1\|5311707_5312178_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_157579444.1\|5271785_5273372_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247582.1\|5277070_5277364_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_026012191.1\|5299732_5300002_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270916
NC_019892.1\|WP_015247594.1\|5303497_5304139_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247599.1\|5307339_5309967_-\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|366777
NC_019892.1\|WP_015247585.1\|5283387_5284611_-\|EstA-family-serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_019892.1\|WP_015247598.1\|5306819_5307293_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247586.1\|5284717_5285713_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_019892.1\|WP_015243913.1\|5310157_5311501_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_019892.1\|WP_015247597.1\|5305661_5306711_+\|lectin-MOA-related-protein	unknown	unknown	gnl\|CDD\|375493
NC_019892.1\|WP_015247595.1\|5304903_5305239_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020467538.1\|5300030_5300663_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270916
NC_019892.1\|WP_020467535.1\|5282619_5283132_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|224168
NC_019892.1\|WP_015247593.1\|5302912_5303371_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015244181.1\|5275064_5276450_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|373239
NC_019892.1\|WP_015247588.1\|5286834_5287926_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_019892.1\|WP_015247581.1\|5273805_5274717_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247599.1\|5307339_5309967_-\|patatin-like-phospholipase-family-protein	gnl\|CDD\|366777	pfam01734, Patatin, Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have been found also in vertebrates.	1.5313e-07
NC_019892.1\|WP_015247597.1\|5305661_5306711_+\|lectin-MOA-related-protein	gnl\|CDD\|375493	pfam18021, Agglutinin_C, Agglutinin C-terminal. This is the C-terminal domain of the alpha chain found in Marasmius Oreades lectin protein (MOA) which binds specifically with Gal.alpha(1,3)Gal-containing sugar epitopes. The enzymatic activity of the MOA may be associated with this domain. The domain has an alpha/beta-fold, which features a central six-stranded, mostly anti-parallel, beta-sheet flanked by three alpha-helices, and a short two-stranded beta-sheet.	2.60314e-26
NC_019892.1\|WP_020467538.1\|5300030_5300663_+\|hypothetical-protein	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.14754e-26
NC_019892.1\|WP_015243913.1\|5310157_5311501_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.86613e-05
NC_019892.1\|WP_026012191.1\|5299732_5300002_+\|hypothetical-protein	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	9.40595e-08
NC_019892.1\|WP_020467535.1\|5282619_5283132_-\|N-acetyltransferase	gnl\|CDD\|224168	COG1247, COG1247, Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane].	1.11547e-39
NC_019892.1\|WP_015247588.1\|5286834_5287926_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.27315e-60
NC_019892.1\|WP_015247586.1\|5284717_5285713_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.76099e-17
NC_019892.1\|WP_015247585.1\|5283387_5284611_-\|EstA-family-serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.96629e-57
NC_019892.1\|WP_015244181.1\|5275064_5276450_+\|IS4-family-transposase	gnl\|CDD\|373239	pfam14706, Tnp_DNA_bind, Transposase DNA-binding. This domain occurs at the C-terminus of transposases including E. coli tnpA. TnpA encodes a transposase and an inhibitor protein, the inhibitor only differs from the transposase by the absence of the N-terminal 55 amino acids, which includes most of this domain. This domain consists of alpha helices and turns, and functions as a DNA-binding domain.	3.82088e-18

>NC_019892.1|WP_015247588.1|5286834_5287926_+|serine-hydrolase
MTRPIAFLLLFATTPAFAQAPPYARADKVDAVAGAEVAKQKLVGLAVVVIDEGRIAWSKGYGYADQEKAVPVDPAGTQFRWASISKPVTAVAALQLAESGRLDLDADVRTYVPEFPDKGEKITPRNLLCHQGGIVHYTNGKVVRSEKEYADPHPFADVVVAMDMFKESPLVNRPGEKYAYSTHGFILLSAVVERAGKQRFADQVRARVAEPLGMTNFRPDYQWEDIPNRAIGYTRTDGVIARRDEDHDVSWKLGGGGFTSSATDLARFGVGLLQRKLVSEETEKLMWTVNKPADPQGAKPYGLGFFVLDLPGGRTIVGHDGSQEKTRTALMLDPKGQRGIALMTNSEWCDAAQLALTLMDELK
>NC_019892.1|WP_015247587.1|5286072_5286360_+|hypothetical-protein
MTDDEPSSPISRGPFFSNEGPDDGLVMLGKAPFLEVLDGARKVIGTAWPVGAIPSRKGMAQLWFLEVGQIGLPGVYVCRRKIFVRIMDTAEDSPD
>NC_019892.1|WP_015247586.1|5284717_5285713_-|alpha/beta-hydrolase
MSQATAPPHRFSISAGRDDRPANTLGRARGRRFRPLAAFSLLTALTALSCTRAEDPAATAPNRQSVDVGGYKLTLLTRGQGTPTVVIEPGMGLAAVESDEWTVVCEEIAKTNRVCLYDRAGLGTSDPAPTRPRTSQDIARDLHALLINAKVPGPYVLVGHSIGGLNVRVFADLYPDEVAGVVLVDVTHPDQESKWLASLPAESPEELPALKKSRELLTSRLERGSDNPDGMDVVTSREQVRSTSTLGDKPLAVLTHSPDWKMVPDLPDAILKPLEQISQDLQASLPALSTNSSHKVAKKAGHAIHLDEPSLVIEAVREVLEKANGNTAKLR
>NC_019892.1|WP_015247585.1|5283387_5284611_-|EstA-family-serine-hydrolase
MSNVDGLVEDGWGQVADTFRANFKEGKDLGAACCVYVDGRAVVDLWGGLADREKNRPWERDTVALVASTTKGATAICAHLLVQRGQLDLDAPVIRYWPEFGAAGKEKIPVRWLLSHQAGLPYVDTPVTFEEACAWDPLIRALEVQKPLWTPGTEHLYHAMTYGFLVGEVIRRITGRSPGTFFAEEIAQPLGLSAWIGLPEEVEPRIARIEAAPFPYKSMEDLAPDFAKLMGLDLAVAVTLVKDVYGPGSAFMKAGAVGDVTGENVLSRAYRAAEFPGANMFANAHSIARMYAATVSDVDGIRLLQPDTVAAMTVAQTDRTRMHGAPPELLPATKNLFNMSLGFVRSAPPVMSMFGPASFGHPGSGGSLGAADPESRVGFGYVPNLWAATMVDPRAIELTSAVAKCLG
>NC_019892.1|WP_020467535.1|5282619_5283132_-|N-acetyltransferase
MFIRDATEADLPAIVDIYNQSIPAGWSTADTQPITVADRLDWFRKFDPARRPIWVAEVDGQIAATAYLSSFYGGRAAYDATAEVSLYIATAFQRRGIGRQFKQWVIAECPRLGVTTLLSMHFDHNEATRRINESLGFQPLGHLTEIALVQGTKRGLVISALRIPPKPETP
>NC_019892.1|WP_015247583.1|5277413_5278121_-|hypothetical-protein
MIARFAVVILASQWIACLCASAQSHLEPENGILNATDSTWNSSKRIREVLLKEATYYHLARMVCLPSFDEPEWVVTVVRQDGEELDAPHTYFVEYVGAETKLFLAKGAQDVQVKRSRAPLDRSTAESLNKTWRRMLRSTRYPKDPRLGADGVNYHFSRFVPLIDRGRNDPLAGWEQGKIWTPDEDSLCGELVAIGEELKRYAVALPADRDRIHDRIRAKEHQLKAKLNRESKTAP
>NC_019892.1|WP_015247582.1|5277070_5277364_+|hypothetical-protein
MAFWPIVGWSSVCLGCVAALYGLHRLGLRLEEQGYIYYWYKKPSGSAAGCFVALQRAVEPQVQHVEQARAEQNRDGDDESAGRRRAQEAEEGQEPMN
>NC_019892.1|WP_015244181.1|5275064_5276450_+|IS4-family-transposase
MSPTLTDPEAWAQANFAGADLGDKRRETRLIRLATQIAVDSSASLPKATGNWDDLRAAYRLLDSSAVNFRAIAEPHWRSIRETSPEMALILDDTTEIDFGCTRQIQGVGPVGTGTGQGFMIHSGLMVSHKDEVVYGLAGQILFHRKPVPKGESRTQRRKRDRESEVWGKLIELIGSPPQNTRWVHVMDRGSDDFEVYCRAQRQGVDWVGRVKSLHRRVQGADGLERPLQEELESVPQAGCFTLKLRSRPGLPARTAKLTVTFVRATMLVPRQPADSLKGLDPQPIAQYVVCVREVDPPASVKEPIEWVLYTSLEVACLEDALRIISYYEKRWLIEEWHKALKSGCSAADHQLKASHRLEALTGLLSVVAVRLLQLKGIARSEPERPAIEAAPPKYVAVLRAFRRTTEALPWGTYQFFRELAKLGGFLGRKGDGEPGWQTIWRGWMKLQAMVQGAELDLRLE
>NC_019892.1|WP_015247581.1|5273805_5274717_+|hypothetical-protein
MGGNGVRVPHFVIALAYLLSSLAIPSVSYAADLKPYPLPPAARADIEKLAASSNVLILGETHGTQEVPELTASLLEPLAKLDYHILAIEVPNKEQASLLAWAHGKTERVPDFFANPSGDGRGNAQLLSLVRIAVSPPFRWQVICFDDTESMLEQQRLILMQKKPTGGAEAPQLTAEDGIALWRARDAAMAANLLRETKSLKTTSKILAVCGNLHARVTNDMQDPDLSKLWPSFAGMLKQGQPAWRVSSVNIEFYRGAFFNEGKVRTIQGRPLEHAVVRSADQTGWNLELSLPEATPATFHFSK
>NC_019892.1|WP_157579444.1|5271785_5273372_+|hypothetical-protein
MMRNRLGVLGLVAVLFAGTASGQNVPKPSTSDSVNAEKETRYLAFQIFTHYSSDPKVAVLLNSGSREPVLPGTAALRNWVEDIKRRIGTVGDERTRLAVMLGPLCFEQDDAEVTRFIELAFRLALETDVAVGFHIDDSMFWAKRKDLWSDPKNVEALDWDGTPCTGRRLNWGKEPTAAPPQMCFNSKAIQREVQQRSALLGKAIQAGVKSLQEHKKPELFAGVIAGWETMIGQDFKTGKYLGYRALMNRGFSRERPPQDMNLEREKVVQEFIEHWTKGLAEAGVSPQKIYSHTAFLSRRAFNLGDDKAITYMKRDKESAYSQHNHFAPPSMAFGENHRPGFSTYPQPGLFEDIYEQMARHKQVGWASSEGTNMQPSSGPGQTGMDMETYLAKMFNHGATLVNLFSWGVGGDAMKTMGFRVVTEGEEAIRAYRKFLKGDALVEAKTEESLMERLPPKIHKIQKELPGWIEKAEVDSKKKAMSLMKQLQEQMKAKNFEEVEETANSLLKMMKGASAPAAAQDTPKEAGRG
>NC_019892.1|WP_026012191.1|5299732_5300002_+|hypothetical-protein
MRNISALLPQIPGFQVERELGRGGMGVAYLARQESRNRSVVLKFIGGAARLTLLNWHASALRLGPSLVLLIRTLSEFTMSAFVSQAACL
>NC_019892.1|WP_020467538.1|5300030_5300663_+|hypothetical-protein
MIAPAIRSLWEEATHEHRSPDESHVAVSQYVAEWLEQVRQPLPATAPPLENLTRFGAILGTPEYMAPEQMCGNTDSTGPRADLYALGVTMYQMLVGHRPNAVIQYEAGVHYPLPSRTRVSSELEAICNQCLRYRAEDRYPHVGELVADLDRFLGGYAVVAALPECAGAVGPNRSAKTETAPGTTVAQSHPQESTRSWWPLSRRKVSRKES
>NC_019892.1|WP_015247593.1|5302912_5303371_+|hypothetical-protein
MEAKEPLPGPGCFQWNRGGWFGGQLGSTVWMLVGGVVLVPYALDVACVWLACFAVANAIGAWLWRGRDRLPPYPALQALLATCGVSSLVALAALHILRPGLRITRPPGIWLADEPQYLPWVLVLFLAVMTSCSLRERSARRQVLRSKGPSTP
>NC_019892.1|WP_015247594.1|5303497_5304139_+|hypothetical-protein
MFVERASIAQVMAFVALAAVNLGVFRALPLEVVRFPTLWVFLGAIDVVIFRKLICVRSLRAFHYTFLIVFVLAWIVMANLVVTARFHPLGLLVQWYQQITTDKINVVSLDSFDFYELWMTCFLSFALAVAIGLVAAWFESRRNWDIAACLRGALAGFGIANLLAVIDGAVWGWGVVSPVRMVGRLILVGVCVILGGVVGLSKLKSNTPGRRVP
>NC_019892.1|WP_015247595.1|5304903_5305239_-|hypothetical-protein
MCPNNLVLDPENSANVTIDEDPERWPNDQQASADPSQIATTQVAMSWYLTVAEQLAMDRAIPSDAATEKAFGDVDQKTKRVERLNALKNEAFKTVWAPDARPTCTSSTSEP
>NC_019892.1|WP_015247597.1|5305661_5306711_+|lectin-MOA-related-protein
MDEILVEVRNNVAQPRPARVVEPWDRKDRPQVPEPTTAQRLGITPRFSDPIPLSAIDPNVPYLIVDEYDRILCPDNYGQSYWDYMFFGKFEDYAGYVLGTQFSMNPLAGYAALHLGPPHSQVALYAYGSSTKYEYLIYGQPGYAKSPIARMKAVNSSGDHFNLRYEIAGGDMYLCCDAASWNWAYVGNTTYRRIPLTARKFYLRKADLFTLFRETWPSADINEMSFRNLDDEYELVHAAKASQIYNNSGLGNFRYVKEVFDCDDFGYVMKAAASKQAYDDNRAAGGAVVRPYALGFVWGISGPYSHVANVFVDYTGTVKILEPQSGRIVDGKDWQYDSNHKYKPYFICL
>NC_019892.1|WP_015247598.1|5306819_5307293_-|hypothetical-protein
MLPAIAKRQESALKQGDGPVPQPENEGPAVPDAPGWMERMAMPVASWAAPTSGEESAADHFDIPVEGDRPSAETSEAKAIPRPGPSPIPIFGLGLVGLALIGQRRRRNSQHRSSGPRSPVSRESTRLQIRQSLPHAVSRQRYQEQETGGWDGFLSCL
>NC_019892.1|WP_015247599.1|5307339_5309967_-|patatin-like-phospholipase-family-protein
MDTLQTVLALIVFVGLVLVYREFLGSLLRFLGDHPSQAIILIILYAIVYGQIGNALGIPYLFWNEEPVTRLFAAAAATLLLAVVGVNTYFLIHDERHQAGMSRVDSFLHRRSLRWPLTFWERSRDEAETAWELTRFLRLVRLPFLAILVLPAVLPGAWFCSGVPKYAPVVDTLRQTHAWFTGVPDVTRNPWAWLTGVVVWCGGVVFGVVVVKVIIYVAPWVTRKVARPLVAWLSRRTEAVDEITAIGLRKRVTLATFFLVVIAAYALAASPLFYEPDAVGQWLWPTGYGGYGGFSPAFCICTLLGMASLVTASMSFVRRRLRIVLVLGAFVWIGLANRDDFKLRFEHISYATKSKLPENTEEKFGDTTPDPHLASNDQALGHWLEHIHEREGRDKPKLVVVCVTGGAIRSGYWSTVVLKRLGETIELDRFHDHVRVIAGSSGGMVGAAYYVAWLRSGREFDLRNAVPLQSLWPVARHMTLRDPLKMLLPFRLGGGDRGIALEQDWTVLRNLRFADLRTAEAEGKLPSLIFSPMLVDDGRRLLISNLDLRRLSPPGQVPRAMAHTRGSALSDKGTGGEMRPYSLTATEYYKMFAEQDQGLQPDPGLLLSTAARMSASFPFISPAVNLPSDPPLRVVDAGYYDNYGVNVAAAWIGMNREWLAENCSGVLLVQIRDSMNRRERLGYPTPVTSAMGEVLKGFQFFTSVTDGILAARVSSSMFRNDAQVAALSDVFAGLTKNRAFFTTAFFENSANVTIDEDLERWPNDQQASTDPSQIATTQVAMSWYLTVAEQLAMDRAIPSDAAAEKAFGNVDQKTKRVERLNALKNEAFKTVWAPRRQAYLYLQYERAMNYERLQSLKDWWGKDHSSPAANLAITE
>NC_019892.1|WP_015243913.1|5310157_5311501_-|IS4-family-transposase
MNHDQESPAVVDLGEAVRMFHRLVPPDVLHAQKPPTLSTVFTPWVVVWLMIYQRLTCNATMATAVGELARLSADVLPDNKRAREKSFSANTGGFSRARDRLPVEMAQRAADEVSAALIAKSPPSVKGRNAFLVDGSTLSLAPTDALRKTYPPARNQHGESHWPILHLVAAHELSSGVTVRPEVGAMYGPAAIGEVPLSAGLMPRLPVGSVLIADRNFGVFAFAWLANQAGHDFVLRLTEKRFRSMVRQGKAQGKDQWELTWQPNRWERKSNPQWPADATLRVWLHEVRISEKLTLWLVSRLPDEGCELAAIYGQRQNIETDLRDLKRTLRLEEMRGRSTEMVAKELASATVAYNMANLIRRMAAARVEIAPRRLSFNRVWSLVKVLLLESLDTTDPAKIQERIDLVLRMSGQCKLANRPGRHYPREVIARRRKFPLRPRKRGLKSRK
>NC_019892.1|WP_015247600.1|5311707_5312178_-|hypothetical-protein
MRVPKIRIRTWMIVVAVVGLGCSQIANNPSIGIILAGPLIGSPLIGLRMRNRLHGFLVGGIVGSLAETGLLVFFREPMTRFIALVIGPARTVDAPWPLANVAVGFMVGLAFGVAYLMRAAIVSPAYIVDSSAMRIKEAPKIDPEWGANADLADHPR

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Crispr_ID: NC_019892_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_17

5318064-5322402

Orphan

Consensus_repeat	Method
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CRISPRCasFinder
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CRT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	PILER-CR
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	PILER-CR
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CRISPRCasFinder

59 spacers

The CRISPR arrays of NC_019892_17

>merge|NC_019892|17|5318064-5322402|CRISPRCasFinder,CRT,PILER-CR,PILER-CR,CRISPRCasFinder
GGCTCCAATAGGCCACGGCTCGGAAGCCGTGGAAGACCAGGAGTGCGTCATTGATGACGACAAGCTGCCTCATGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGCCTTAGAAGTTGCCGCCAACGCTGAACGATACCAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTCGCTGCACAAAATCGCATGCAACACCAGCAGGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCGAGACGCCACAAAAACATTTGCACGCGAGTTTATGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCAGGCCGCTAAGGACCGCAAGAAGCAGCTGAGAACGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCTCCAACGGTCGATCGACGCGTTCCGCAAGGAAATGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACAAAGCTTAAGCGATTAGTTAAACGCATCATGCCCGGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTCCACACCGTGGACGCTCACACGAAGCATTACATCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGAGGGGTTCGCGGCATGGCGAGACAAGGCGGCCGAAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGAGCATTGGACGGCCGAGGTTACACCTGCCGGGGTCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACACCAGTCTGAGAATCCCGATTTCTGATCCTTACGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACATGATGATGGGCGGAAAGTATCCACCGACCCAAGAAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCAAGTAGCAGGTCGATCGCGCGTCGCCGGCCAGATGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACACGGGTTCGCAAAAGACTGGGAAATTAGTCGGGAAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTCTGGGCCTTGGGTTAACTGGCGTGGCGAGATGGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGGTATGGGTCGGCGGGATATGGCTCTCGATGGCGGTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGAGTCGTCCAAGTGGTTGGGCATCGACCCCATGTTGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACACAGCAGATCGCGGATAACGAGTCGGCCCGCGCCGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGATGACACGCTGGCACTTCGGGCCGCGATCGCAACCGGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGAAATTGGCTTGGACGGTCAGGGTGTTGCCGTTGATTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTGGCCAGGCGTGAGATTATCCTGCACGCTCGCGCTATCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCACGTTGCCGGTGATGATGAGGCCGGAGTAAGCGCCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCCTTCGGCTCGAAACCGGCCTCGAGCACGAACGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCTGATTCACTAGCTAGATTTAAGCCAGATTTCGGAGACGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCGAGATTCGGACGGGTAAGATTATCGAGTTGACGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTGAGGCCGGTAGTGGCCGCAGAATCCAACTCCCGTAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTCCTTCCGGCTGAACGTCAGAGTGTCTCCACCCGTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTGCCTTGACTTGGGCCTTCACGGAAGACTGGATGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGGATTATTGATGCCTGGATGGGGCACCAGACGGAAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTCGCCCGGGAGTGGTCGCGCAAGCGGCCACATCTGCGTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCAGAGCGTTGAAGGCGTGCCTCTCGAAATGACGAGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGCCGACGGCAGCCGAGCCGATCACGGAAGCCGAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGATCCTGAACGCGAAGCGCGGGCTCCCCTGGTCGGTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGACCTGGTGAACGCCGACTTCGACACACCCTGACGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGTCCTCACGACTGGGGGGCAACGGTACAAGGAAACGGCTCGGAAGCCGTGGAAGACTCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGTATCGAGCGAGCGCGTAAATTGCCGGCCTTGCCAGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCCTGCGAGGGGTCCTCTTGCAGCGATTCAGCGACCGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGAAGCTCAGCAAACATTGGCCAAGGAATTCGGGCTGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACACGAAATCAAGTCCCTGGTCGAGCAGGGGTTAAAAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGAGGTCGGGCAGGCCAAATTACGTCGCTGGTGTTGTGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACACGTTCACGCCCGGGGCGGTCGCGACGCACGGAAACGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTGGATGAAGCCGAGGCGGATATCGCATCGATTACCGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCCAACATGATCGCCCTGGTCGACCATCAAATCGCAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGCGTCGCTGGACTGGAAATTCTCCTCGGCAAGAGCGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGAGATATTTTCGCCCTCATCGAAGAATCGGGCGGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACAACCACGGGTGCGGGAATTCCGCTCGTTCCGTAGACGGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTATGGTCCATTGCGGAACATAATCACTTATTCCCTCAAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGAATAGCTTCACAGCGGTGGAATCGGCGCGAGGCGAGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCAAGGCGGGTGGACACGCCAAAGCCGCGAAGACTGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGGGTGGGAGTCCGCGGCTTTGCCCATCCTCGGTGTCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACAAGAGCTCGGAGTGTTGGGTAGCCATGATCGTTGGTCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCTGGGCCTGCTCGTGGACGACAGTGCGCGGTGGGTCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTCTGGATGTGAACACAAATACAATAATAGGGGACGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTGCGGCGATACTGTTCAATAAGACAGCAAAGGCCGCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTTGAAACGCAGGCTGATGCCGGCCGCACAACACATGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCCGAGGCAAGCGTCCAATTCCGCTCGCCTCTCATGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACATGTCGCCGCCAGCAAGCCGCAGCCGCTCATTCTCGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC

>NC_019892|17|16|5318064-5320663|CRISPRCasFinder
GGCTCCAATAGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGGAGTGCGTCATTGATGACGACAAGCTGCCTCAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGCCTTAGAAGTTGCCGCCAACGCTGAACGATACCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCGCTGCACAAAATCGCATGCAACACCAGCAGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAGACGCCACAAAAACATTTGCACGCGAGTTTAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGGCCGCTAAGGACCGCAAGAAGCAGCTGAGAAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCTCCAACGGTCGATCGACGCGTTCCGCAAGGAAAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAAGCTTAAGCGATTAGTTAAACGCATCATGCCCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCCACACCGTGGACGCTCACACGAAGCATTACATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGGGGTTCGCGGCATGGCGAGACAAGGCGGCCGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGAGCATTGGACGGCCGAGGTTACACCTGCCGGGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACCAGTCTGAGAATCCCGATTTCTGATCCTTACGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGATGATGGGCGGAAAGTATCCACCGACCCAAGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGTAGCAGGTCGATCGCGCGTCGCCGGCCAGATG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGGGTTCGCAAAAGACTGGGAAATTAGTCGGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCTGGGCCTTGGGTTAACTGGCGTGGCGAGATGGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGTATGGGTCGGCGGGATATGGCTCTCGATGGCGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGTCGTCCAAGTGGTTGGGCATCGACCCCATGTTGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCAGATCGCGGATAACGAGTCGGCCCGCGCCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATGACACGCTGGCACTTCGGGCCGCGATCGCAACCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAAATTGGCTTGGACGGTCAGGGTGTTGCCGTTGATT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGCCAGGCGTGAGATTATCCTGCACGCTCGCGCTATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCACGTTGCCGGTGATGATGAGGCCGGAGTAAGCGCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCTTCGGCTCGAAACCGGCCTCGAGCACGAACGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGATTCACTAGCTAGATTTAAGCCAGATTTCGGAGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAGATTCGGACGGGTAAGATTATCGAGTTGACGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGAGGCCGGTAGTGGCCGCAGAATCCAACTCCCGTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCCTTCCGGCTGAACGTCAGAGTGTCTCCACCCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGCCTTGACTTGGGCCTTCACGGAAGACTGGATGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGATTATTGATGCCTGGATGGGGCACCAGACGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCGCCCGGGAGTGGTCGCGCAAGCGGCCACATCTGCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGAGCGTTGAAGGCGTGCCTCTCGAAATGACGAGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGACGGCAGCCGAGCCGATCACGGAAGCCGAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATCCTGAACGCGAAGCGCGGGCTCCCCTGGTCGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GACCTGGTGAACGCCGACTTCGACACACCCTGACG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGTCCTCACGACTGGGGGGCAACGGTACAAGGAAACGGCTCGGAAGCCGTGGAAGACTCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTATCGAGCGAGCGCGTAAATTGCCGGCCTTGCCAGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCTGCGAGGGGTCCTCTTGCAGCGATTCAGCGACCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGAAGCTCAGCAAACATTGGCCAAGGAATTCGGGCT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGAAATCAAGTCCCTGGTCGAGCAGGGGTTAAAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGGTCGGGCAGGCCAAATTACGTCGCTGGTGTTGTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGTTCACGCCCGGGGCGGTCGCGACGCACGGAAAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGATGAAGCCGAGGCGGATATCGCATCGATTACCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCAACATGATCGCCCTGGTCGACCATCAAATCGCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGTCGCTGGACTGGAAATTCTCCTCGGCAAGAGCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGATATTTTCGCCCTCATCGAAGAATCGGGCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AACCACGGGTGCGGGAATTCCGCTCGTTCCGTAGACGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TATGGTCCATTGCGGAACATAATCACTTATTCCCTCAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAATAGCTTCACAGCGGTGGAATCGGCGCGAGGCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGGCGGGTGGACACGCCAAAGCCGCGAAGACTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGGTGGGAGTCCGCGGCTTTGCCCATCCTCGGTGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAGAGCTCGGAGTGTTGGGTAGCCATGATCGTTGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGGGCCTGCTCGTGGACGACAGTGCGCGGTGGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCTGGATGTGAACACAAATACAATAATAGGGGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGCGGCGATACTGTTCAATAAGACAGCAAAGGCCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGAAACGCAGGCTGATGCCGGCCGCACAACACAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGAGGCAAGCGTCCAATTCCGCTCGCCTCTCAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGTCGCCGCCAGCAAGCCGCAGCCGCTCATTCTC


>NC_019892|17|5|5318064-5322402|CRT
GGCTCCAATAGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGGAGTGCGTCATTGATGACGACAAGCTGCCTCAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGCCTTAGAAGTTGCCGCCAACGCTGAACGATACCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCGCTGCACAAAATCGCATGCAACACCAGCAGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAGACGCCACAAAAACATTTGCACGCGAGTTTAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGGCCGCTAAGGACCGCAAGAAGCAGCTGAGAAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCTCCAACGGTCGATCGACGCGTTCCGCAAGGAAAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAAGCTTAAGCGATTAGTTAAACGCATCATGCCCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCCACACCGTGGACGCTCACACGAAGCATTACATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGGGGTTCGCGGCATGGCGAGACAAGGCGGCCGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGAGCATTGGACGGCCGAGGTTACACCTGCCGGGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACCAGTCTGAGAATCCCGATTTCTGATCCTTACGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGATGATGGGCGGAAAGTATCCACCGACCCAAGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGTAGCAGGTCGATCGCGCGTCGCCGGCCAGATG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGGGTTCGCAAAAGACTGGGAAATTAGTCGGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCTGGGCCTTGGGTTAACTGGCGTGGCGAGATGGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGTATGGGTCGGCGGGATATGGCTCTCGATGGCGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGTCGTCCAAGTGGTTGGGCATCGACCCCATGTTGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCAGATCGCGGATAACGAGTCGGCCCGCGCCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATGACACGCTGGCACTTCGGGCCGCGATCGCAACCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAAATTGGCTTGGACGGTCAGGGTGTTGCCGTTGATT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGCCAGGCGTGAGATTATCCTGCACGCTCGCGCTATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCACGTTGCCGGTGATGATGAGGCCGGAGTAAGCGCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCTTCGGCTCGAAACCGGCCTCGAGCACGAACGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGATTCACTAGCTAGATTTAAGCCAGATTTCGGAGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAGATTCGGACGGGTAAGATTATCGAGTTGACGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGAGGCCGGTAGTGGCCGCAGAATCCAACTCCCGTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCCTTCCGGCTGAACGTCAGAGTGTCTCCACCCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGCCTTGACTTGGGCCTTCACGGAAGACTGGATGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGATTATTGATGCCTGGATGGGGCACCAGACGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCGCCCGGGAGTGGTCGCGCAAGCGGCCACATCTGCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGAGCGTTGAAGGCGTGCCTCTCGAAATGACGAGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGACGGCAGCCGAGCCGATCACGGAAGCCGAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATCCTGAACGCGAAGCGCGGGCTCCCCTGGTCGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GACCTGGTGAACGCCGACTTCGACACACCCTGACG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGTCCTCACGACTGGGGGGC
AACGGTACAAGGAAACGGCTCGGAAGCCGTGGAAGAC	TCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTATCGAGCGAGCGCGTAAATTGCCGGCCTTGCCAGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCTGCGAGGGGTCCTCTTGCAGCGATTCAGCGACCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGAAGCTCAGCAAACATTGGCCAAGGAATTCGGGCT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGAAATCAAGTCCCTGGTCGAGCAGGGGTTAAAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGGTCGGGCAGGCCAAATTACGTCGCTGGTGTTGTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGTTCACGCCCGGGGCGGTCGCGACGCACGGAAAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGATGAAGCCGAGGCGGATATCGCATCGATTACCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCAACATGATCGCCCTGGTCGACCATCAAATCGCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGTCGCTGGACTGGAAATTCTCCTCGGCAAGAGCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGATATTTTCGCCCTCATCGAAGAATCGGGCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AACCACGGGTGCGGGAATTCCGCTCGTTCCGTAGACGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TATGGTCCATTGCGGAACATAATCACTTATTCCCTCAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAATAGCTTCACAGCGGTGGAATCGGCGCGAGGCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGGCGGGTGGACACGCCAAAGCCGCGAAGACTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGGTGGGAGTCCGCGGCTTTGCCCATCCTCGGTGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAGAGCTCGGAGTGTTGGGTAGCCATGATCGTTGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGGGCCTGCTCGTGGACGACAGTGCGCGGTGGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCTGGATGTGAACACAAATACAATAATAGGGGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGCGGCGATACTGTTCAATAAGACAGCAAAGGCCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGAAACGCAGGCTGATGCCGGCCGCACAACACAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGAGGCAAGCGTCCAATTCCGCTCGCCTCTCAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGTCGCCGCCAGCAAGCCGCAGCCGCTCATTCTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC

>NC_019892|17|7|5318137-5320515|PILER-CR
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGCCTTAGAAGTTGCCGCCAACGCTGAACGATACCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCGCTGCACAAAATCGCATGCAACACCAGCAGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAGACGCCACAAAAACATTTGCACGCGAGTTTAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGGCCGCTAAGGACCGCAAGAAGCAGCTGAGAAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCTCCAACGGTCGATCGACGCGTTCCGCAAGGAAAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAAGCTTAAGCGATTAGTTAAACGCATCATGCCCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCCACACCGTGGACGCTCACACGAAGCATTACATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGGGGTTCGCGGCATGGCGAGACAAGGCGGCCGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGAGCATTGGACGGCCGAGGTTACACCTGCCGGGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACCAGTCTGAGAATCCCGATTTCTGATCCTTACGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGATGATGGGCGGAAAGTATCCACCGACCCAAGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGTAGCAGGTCGATCGCGCGTCGCCGGCCAGATG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGGGTTCGCAAAAGACTGGGAAATTAGTCGGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCTGGGCCTTGGGTTAACTGGCGTGGCGAGATGGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGTATGGGTCGGCGGGATATGGCTCTCGATGGCGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGTCGTCCAAGTGGTTGGGCATCGACCCCATGTTGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCAGATCGCGGATAACGAGTCGGCCCGCGCCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATGACACGCTGGCACTTCGGGCCGCGATCGCAACCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAAATTGGCTTGGACGGTCAGGGTGTTGCCGTTGATT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGCCAGGCGTGAGATTATCCTGCACGCTCGCGCTATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCACGTTGCCGGTGATGATGAGGCCGGAGTAAGCGCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCTTCGGCTCGAAACCGGCCTCGAGCACGAACGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGATTCACTAGCTAGATTTAAGCCAGATTTCGGAGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAGATTCGGACGGGTAAGATTATCGAGTTGACGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGAGGCCGGTAGTGGCCGCAGAATCCAACTCCCGTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCCTTCCGGCTGAACGTCAGAGTGTCTCCACCCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGCCTTGACTTGGGCCTTCACGGAAGACTGGATGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGATTATTGATGCCTGGATGGGGCACCAGACGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCGCCCGGGAGTGGTCGCGCAAGCGGCCACATCTGCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGAGCGTTGAAGGCGTGCCTCTCGAAATGACGAGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGACGGCAGCCGAGCCGATCACGGAAGCCGAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATCCTGAACGCGAAGCGCGGGCTCCCCTGGTCGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGACCTGGTGAACGCCGACTTCGACACACCCTGACGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGTCCTCACGACTGGGGGGCAACGGTACAAGGAAACGGCTCGGAAGCCGTGGAAGACTCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTATCGAGCGAGCGCGTAAATTGCCGGCCTTGCCAGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCTGCGAGGGGTCCTCTTGCAGCGATTCAGCGACCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGAAGCTCAGCAAACATTGGCCAAGGAATTCGGGCT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGAAATCAAGTCCCTGGTCGAGCAGGGGTTAAAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGGTCGGGCAGGCCAAATTACGTCGCTGGTGTTGTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGTTCACGCCCGGGGCGGTCGCGACGCACGGAAAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGATGAAGCCGAGGCGGATATCGCATCGATTACCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCAACATGATCGCCCTGGTCGACCATCAAATCGCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGTCGCTGGACTGGAAATTCTCCTCGGCAAGAGCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGATATTTTCGCCCTCATCGAAGAATCGGGCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AACCACGGGTGCGGGAATTCCGCTCGTTCCGTAGACGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TATGGTCCATTGCGGAACATAATCACTTATTCCCTCAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAATAGCTTCACAGCGGTGGAATCGGCGCGAGGCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGGCGGGTGGACACGCCAAAGCCGCGAAGACTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGGTGGGAGTCCGCGGCTTTGCCCATCCTCGGTGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAGAGCTCGGAGTGTTGGGTAGCCATGATCGTTGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGGGCCTGCTCGTGGACGACAGTGCGCGGTGGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCTGGATGTGAACACAAATACAATAATAGGGGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGCGGCGATACTGTTCAATAAGACAGCAAAGGCCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGAAACGCAGGCTGATGCCGGCCGCACAACACAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGAGGCAAGCGTCCAATTCCGCTCGCCTCTCAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGTCGCCGCCAGCAAGCCGCAGCCGCTCATTCTC


>NC_019892|17|8|5320758-5322402|PILER-CR
	GGCCTTAGAAGTTGCCGCCAACGCTGAACGATACCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCGCTGCACAAAATCGCATGCAACACCAGCAGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAGACGCCACAAAAACATTTGCACGCGAGTTTAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGGCCGCTAAGGACCGCAAGAAGCAGCTGAGAAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCTCCAACGGTCGATCGACGCGTTCCGCAAGGAAAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAAGCTTAAGCGATTAGTTAAACGCATCATGCCCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCCACACCGTGGACGCTCACACGAAGCATTACATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGGGGTTCGCGGCATGGCGAGACAAGGCGGCCGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGAGCATTGGACGGCCGAGGTTACACCTGCCGGGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACCAGTCTGAGAATCCCGATTTCTGATCCTTACGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGATGATGGGCGGAAAGTATCCACCGACCCAAGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGTAGCAGGTCGATCGCGCGTCGCCGGCCAGATG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGGGTTCGCAAAAGACTGGGAAATTAGTCGGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCTGGGCCTTGGGTTAACTGGCGTGGCGAGATGGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGTATGGGTCGGCGGGATATGGCTCTCGATGGCGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGTCGTCCAAGTGGTTGGGCATCGACCCCATGTTGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCAGATCGCGGATAACGAGTCGGCCCGCGCCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATGACACGCTGGCACTTCGGGCCGCGATCGCAACCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAAATTGGCTTGGACGGTCAGGGTGTTGCCGTTGATT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGCCAGGCGTGAGATTATCCTGCACGCTCGCGCTATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCACGTTGCCGGTGATGATGAGGCCGGAGTAAGCGCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCTTCGGCTCGAAACCGGCCTCGAGCACGAACGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGATTCACTAGCTAGATTTAAGCCAGATTTCGGAGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAGATTCGGACGGGTAAGATTATCGAGTTGACGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGAGGCCGGTAGTGGCCGCAGAATCCAACTCCCGTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCCTTCCGGCTGAACGTCAGAGTGTCTCCACCCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGCCTTGACTTGGGCCTTCACGGAAGACTGGATGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGATTATTGATGCCTGGATGGGGCACCAGACGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCGCCCGGGAGTGGTCGCGCAAGCGGCCACATCTGCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGAGCGTTGAAGGCGTGCCTCTCGAAATGACGAGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGACGGCAGCCGAGCCGATCACGGAAGCCGAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATCCTGAACGCGAAGCGCGGGCTCCCCTGGTCGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACGACCTGGTGAACGCCGACTTCGACACACCCTGACGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACTCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGTCCTCACGACTGGGGGGCAACGGTACAAGGAAACGGCTCGGAAGCCGTGGAAGACTCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTATCGAGCGAGCGCGTAAATTGCCGGCCTTGCCAGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCTGCGAGGGGTCCTCTTGCAGCGATTCAGCGACCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGAAGCTCAGCAAACATTGGCCAAGGAATTCGGGCT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGAAATCAAGTCCCTGGTCGAGCAGGGGTTAAAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGGTCGGGCAGGCCAAATTACGTCGCTGGTGTTGTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGTTCACGCCCGGGGCGGTCGCGACGCACGGAAAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGATGAAGCCGAGGCGGATATCGCATCGATTACCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCAACATGATCGCCCTGGTCGACCATCAAATCGCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGTCGCTGGACTGGAAATTCTCCTCGGCAAGAGCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGATATTTTCGCCCTCATCGAAGAATCGGGCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AACCACGGGTGCGGGAATTCCGCTCGTTCCGTAGACGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TATGGTCCATTGCGGAACATAATCACTTATTCCCTCAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAATAGCTTCACAGCGGTGGAATCGGCGCGAGGCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGGCGGGTGGACACGCCAAAGCCGCGAAGACTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGGTGGGAGTCCGCGGCTTTGCCCATCCTCGGTGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAGAGCTCGGAGTGTTGGGTAGCCATGATCGTTGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGGGCCTGCTCGTGGACGACAGTGCGCGGTGGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCTGGATGTGAACACAAATACAATAATAGGGGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGCGGCGATACTGTTCAATAAGACAGCAAAGGCCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGAAACGCAGGCTGATGCCGGCCGCACAACACAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGAGGCAAGCGTCCAATTCCGCTCGCCTCTCAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGTCGCCGCCAGCAAGCCGCAGCCGCTCATTCTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC

>NC_019892|17|17|5320758-5322402|CRISPRCasFinder
	CAGGAGTGCGTCATTGATGACGACAAGCTGCCTCAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGCCTTAGAAGTTGCCGCCAACGCTGAACGATACCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCGCTGCACAAAATCGCATGCAACACCAGCAGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAGACGCCACAAAAACATTTGCACGCGAGTTTAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGGCCGCTAAGGACCGCAAGAAGCAGCTGAGAAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCTCCAACGGTCGATCGACGCGTTCCGCAAGGAAAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAAGCTTAAGCGATTAGTTAAACGCATCATGCCCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCCACACCGTGGACGCTCACACGAAGCATTACATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGGGGTTCGCGGCATGGCGAGACAAGGCGGCCGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGAGCATTGGACGGCCGAGGTTACACCTGCCGGGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACCAGTCTGAGAATCCCGATTTCTGATCCTTACGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGATGATGGGCGGAAAGTATCCACCGACCCAAGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGTAGCAGGTCGATCGCGCGTCGCCGGCCAGATG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGGGTTCGCAAAAGACTGGGAAATTAGTCGGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTCTGGGCCTTGGGTTAACTGGCGTGGCGAGATGGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GGTATGGGTCGGCGGGATATGGCTCTCGATGGCGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGTCGTCCAAGTGGTTGGGCATCGACCCCATGTTGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACAGCAGATCGCGGATAACGAGTCGGCCCGCGCCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATGACACGCTGGCACTTCGGGCCGCGATCGCAACCGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAAATTGGCTTGGACGGTCAGGGTGTTGCCGTTGATT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGCCAGGCGTGAGATTATCCTGCACGCTCGCGCTATC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCACGTTGCCGGTGATGATGAGGCCGGAGTAAGCGCC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCCTTCGGCTCGAAACCGGCCTCGAGCACGAACGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGATTCACTAGCTAGATTTAAGCCAGATTTCGGAGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGAGATTCGGACGGGTAAGATTATCGAGTTGACGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGAGGCCGGTAGTGGCCGCAGAATCCAACTCCCGTA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCCTTCCGGCTGAACGTCAGAGTGTCTCCACCCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGCCTTGACTTGGGCCTTCACGGAAGACTGGATGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGATTATTGATGCCTGGATGGGGCACCAGACGGAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCGCCCGGGAGTGGTCGCGCAAGCGGCCACATCTGCGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAGAGCGTTGAAGGCGTGCCTCTCGAAATGACGAGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGCCGACGGCAGCCGAGCCGATCACGGAAGCCGAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GATCCTGAACGCGAAGCGCGGGCTCCCCTGGTCGGT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GACCTGGTGAACGCCGACTTCGACACACCCTGACG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGACCGTCCTCACGACTGGGGGGCAACGGTACAAGGAAACGGCTCGGAAGCCGTGGAAGACTCCAGTAGGGATCAACCGACCGCGGCATCTTCACTCAGGCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GTATCGAGCGAGCGCGTAAATTGCCGGCCTTGCCAGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCTGCGAGGGGTCCTCTTGCAGCGATTCAGCGACCG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGAAGCTCAGCAAACATTGGCCAAGGAATTCGGGCT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGAAATCAAGTCCCTGGTCGAGCAGGGGTTAAAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGGTCGGGCAGGCCAAATTACGTCGCTGGTGTTGTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ACGTTCACGCCCGGGGCGGTCGCGACGCACGGAAAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TGGATGAAGCCGAGGCGGATATCGCATCGATTACCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCAACATGATCGCCCTGGTCGACCATCAAATCGCA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GCGTCGCTGGACTGGAAATTCTCCTCGGCAAGAGCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAGATATTTTCGCCCTCATCGAAGAATCGGGCGGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AACCACGGGTGCGGGAATTCCGCTCGTTCCGTAGACGG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TATGGTCCATTGCGGAACATAATCACTTATTCCCTCAA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	GAATAGCTTCACAGCGGTGGAATCGGCGCGAGGCGA
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CAAGGCGGGTGGACACGCCAAAGCCGCGAAGACTG
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CGGGTGGGAGTCCGCGGCTTTGCCCATCCTCGGTGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	AAGAGCTCGGAGTGTTGGGTAGCCATGATCGTTGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CTGGGCCTGCTCGTGGACGACAGTGCGCGGTGGGTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTCTGGATGTGAACACAAATACAATAATAGGGGAC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGCGGCGATACTGTTCAATAAGACAGCAAAGGCCGC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	TTGAAACGCAGGCTGATGCCGGCCGCACAACACAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	CCGAGGCAAGCGTCCAATTCCGCTCGCCTCTCAT
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC	ATGTCGCCGCCAGCAAGCCGCAGCCGCTCATTCTC
GCTTCAATGGGGCCACGGCTCGGAAGCCGTGGAAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_020467545.1\|5332695_5333373_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247594.1\|5303497_5304139_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247600.1\|5311707_5312178_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247605.1\|5323623_5325144_+\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|379080
NC_019892.1\|WP_015243913.1\|5310157_5311501_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_019892.1\|WP_015247599.1\|5307339_5309967_-\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|366777
NC_019892.1\|WP_015247598.1\|5306819_5307293_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247607.1\|5326628_5328728_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370843
NC_019892.1\|WP_015247615.1\|5334975_5335164_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247611.1\|5331458_5332313_+\|sensor-histidine-kinase	unknown	unknown	unknown
NC_019892.1\|WP_015247608.1\|5328852_5329845_-\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015247597.1\|5305661_5306711_+\|lectin-MOA-related-protein	unknown	unknown	gnl\|CDD\|375493
NC_019892.1\|WP_015247601.1\|5312273_5313929_-\|caspase-family-protein	unknown	unknown	gnl\|CDD\|273938
NC_019892.1\|WP_015247614.1\|5333618_5334857_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381331
NC_019892.1\|WP_015247606.1\|5325218_5326346_-\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|317058
NC_019892.1\|WP_015247602.1\|5315038_5316238_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247612.1\|5332335_5332686_+\|STAS-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|379507
NC_019892.1\|WP_015247610.1\|5330376_5331048_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|188247
NC_019892.1\|WP_015247595.1\|5304903_5305239_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247604.1\|5316731_5317931_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247608.1\|5328852_5329845_-\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	1.18008e-43
NC_019892.1\|WP_015247597.1\|5305661_5306711_+\|lectin-MOA-related-protein	gnl\|CDD\|375493	pfam18021, Agglutinin_C, Agglutinin C-terminal. This is the C-terminal domain of the alpha chain found in Marasmius Oreades lectin protein (MOA) which binds specifically with Gal.alpha(1,3)Gal-containing sugar epitopes. The enzymatic activity of the MOA may be associated with this domain. The domain has an alpha/beta-fold, which features a central six-stranded, mostly anti-parallel, beta-sheet flanked by three alpha-helices, and a short two-stranded beta-sheet.	2.60314e-26
NC_019892.1\|WP_015247601.1\|5312273_5313929_-\|caspase-family-protein	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	2.68957e-25
NC_019892.1\|WP_015247614.1\|5333618_5334857_+\|aldo/keto-reductase	gnl\|CDD\|381331	cd19105, AKR_unchar, uncharacterized aldo-keto reductase (AKR) superfamily protein. This family includes a group of uncharacterized AKR superfamily proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance in both health and industrial applications.	1.41819e-89
NC_019892.1\|WP_015247605.1\|5323623_5325144_+\|glycosyltransferase-family-39-protein	gnl\|CDD\|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	0.00018887
NC_019892.1\|WP_015243913.1\|5310157_5311501_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.86613e-05
NC_019892.1\|WP_015247599.1\|5307339_5309967_-\|patatin-like-phospholipase-family-protein	gnl\|CDD\|366777	pfam01734, Patatin, Patatin-like phospholipase. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have been found also in vertebrates.	1.5313e-07
NC_019892.1\|WP_015247606.1\|5325218_5326346_-\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|317058	pfam14606, Lipase_GDSL_3, GDSL-like Lipase/Acylhydrolase family.	1.68158e-65
NC_019892.1\|WP_015247612.1\|5332335_5332686_+\|STAS-like-domain-containing-protein	gnl\|CDD\|379507	pfam14213, DUF4325, STAS-like domain of unknown function (DUF4325). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea, eukaryotes and viruses. Proteins in this family are typically between 99 and 341 amino acids in length. This domain is distantly related to the STAS domain.	1.08719e-13
NC_019892.1\|WP_015247607.1\|5326628_5328728_-\|hypothetical-protein	gnl\|CDD\|370843	pfam10162, G8, G8 domain. This domain is found in disease proteins PKHD1 and KIAA1199 and is named G8 after its 8 conserved glycines. It is predicted to contain 10 beta strands and an alpha helix.	7.56027e-15
NC_019892.1\|WP_015247610.1\|5330376_5331048_-\|hypothetical-protein	gnl\|CDD\|188247	TIGR02795, Uncharacterized_protein_in_oprL_3'region, tol-pal system protein YbgF. Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.	9.26293e-05

>NC_019892.1|WP_015247604.1|5316731_5317931_-|hypothetical-protein
MRRTLTALTLLLGLPLSVVACLWDRDTPADEAKGMPEVVAVLTGRFERNPPRFYEMRLARVTAQLESHPEDLAGYDDAGVACDRLGRGDEAISWMEKKQTQLEKHEDSLPEVKEQRYRYHANLGTFLVHRWVRQGADRSKIDEVKAARDEIAKALEINPNAHFGREKYQLRAIQWIIDPPRAAGLRDLPNLLGWSMETIYKQADPQQADDAVRGLAGLIVLGNAWESVDIFHALSAALQNDTLGFGQNLDGGRNTLAYFAWLRCRELIDAGKNSMLPDAPKGEALKGALLQPDFVEGAPLLTPTFTKLRAEADAWHTARNAFMTRRLNEGHHPDSDPSFWDGYTEQPAPELPTTSISKAANTSPASPDWTILFVVIGIPVLAVGLVAGSLVVRRAKARR
>NC_019892.1|WP_015247602.1|5315038_5316238_-|hypothetical-protein
MRRTLTALALLLGIPLSVGACLWDRDTPADEAKGMPEVVAVLTGRFERNPPRFYEMRLARVTAQLESHPEDLAGYDDAGVACDRLGRGDEAISWMEKKRAILEKHEDSLPEVKEQRYRYHANLGTFLVHRWVRQGADRSKIDEVKAARDEIAKALEINPNAHFGREKYQLQAIQWIIDPPRAAGLQDLPNILGWSMGMIQEQPNAQQADDAVRGLAGLIVLGNAWESVDIFHALNAALQNDTLGFARNREGGRNTLAYFAWLRCRELIDAGKNSMLPDAPKGEALKGTLPRPDFVEGALLLDPIFTKLRAEADAWHTVRNAFMTRRLNEGRHPDSDPSFWDGYTELPAPKLPTISAPDAFHAMLESRKRMGLLVIIGIPGLAVGLIAGSLVVRKAKARR
>NC_019892.1|WP_015247601.1|5312273_5313929_-|caspase-family-protein
MRFLHPRLPGLILAVAGVLAAGPARSQAPKAQAGQKYALLVGVRQYNPNELRELPYSEPDVVELAGLLKDAGYRQVVTLTQTTGATNSRLLPLAENIRATLKGMLEDREPEDSVVLAFAGHGVQFSGSAENYFCPMDAKLADRATLISFADVYRQLEACAAGVRVMLVDACRNDPQSDNSRARSVVKLESVTRPQQRRPPGGVAALFSCSEGEKSFEHAELKHGVFFHYVIEGLKGKADLDKDGTVDVEELARYTKRSVPDFVKEQYGFDVRQMPVLRGEISGLATIVGPLPLEPAPNGTPPLGPTPGTPARPEKDRRSRIGVAFSPLSPAAAQAIGVDPMMKGALVVGLLPGGPAEKAGLKVNDVVTSFNQQPFIELPSFKERLAASAIGKPLTLAYHRNGQEQSVVIVPVPTEEAIFEQEKTTPAKPPEAEDRRRAMPGGGGPQTALQEFGLEVQPLTAELARDAGLKESDGLLIRAVREGSPASAQGLAPGLAITQMVKDKNLQSVKRVSDLEALAEKSEDLTLYVKSSKIPGAFVTLKKARPGPPPR
>NC_019892.1|WP_015247600.1|5311707_5312178_-|hypothetical-protein
MRVPKIRIRTWMIVVAVVGLGCSQIANNPSIGIILAGPLIGSPLIGLRMRNRLHGFLVGGIVGSLAETGLLVFFREPMTRFIALVIGPARTVDAPWPLANVAVGFMVGLAFGVAYLMRAAIVSPAYIVDSSAMRIKEAPKIDPEWGANADLADHPR
>NC_019892.1|WP_015243913.1|5310157_5311501_-|IS4-family-transposase
MNHDQESPAVVDLGEAVRMFHRLVPPDVLHAQKPPTLSTVFTPWVVVWLMIYQRLTCNATMATAVGELARLSADVLPDNKRAREKSFSANTGGFSRARDRLPVEMAQRAADEVSAALIAKSPPSVKGRNAFLVDGSTLSLAPTDALRKTYPPARNQHGESHWPILHLVAAHELSSGVTVRPEVGAMYGPAAIGEVPLSAGLMPRLPVGSVLIADRNFGVFAFAWLANQAGHDFVLRLTEKRFRSMVRQGKAQGKDQWELTWQPNRWERKSNPQWPADATLRVWLHEVRISEKLTLWLVSRLPDEGCELAAIYGQRQNIETDLRDLKRTLRLEEMRGRSTEMVAKELASATVAYNMANLIRRMAAARVEIAPRRLSFNRVWSLVKVLLLESLDTTDPAKIQERIDLVLRMSGQCKLANRPGRHYPREVIARRRKFPLRPRKRGLKSRK
>NC_019892.1|WP_015247599.1|5307339_5309967_-|patatin-like-phospholipase-family-protein
MDTLQTVLALIVFVGLVLVYREFLGSLLRFLGDHPSQAIILIILYAIVYGQIGNALGIPYLFWNEEPVTRLFAAAAATLLLAVVGVNTYFLIHDERHQAGMSRVDSFLHRRSLRWPLTFWERSRDEAETAWELTRFLRLVRLPFLAILVLPAVLPGAWFCSGVPKYAPVVDTLRQTHAWFTGVPDVTRNPWAWLTGVVVWCGGVVFGVVVVKVIIYVAPWVTRKVARPLVAWLSRRTEAVDEITAIGLRKRVTLATFFLVVIAAYALAASPLFYEPDAVGQWLWPTGYGGYGGFSPAFCICTLLGMASLVTASMSFVRRRLRIVLVLGAFVWIGLANRDDFKLRFEHISYATKSKLPENTEEKFGDTTPDPHLASNDQALGHWLEHIHEREGRDKPKLVVVCVTGGAIRSGYWSTVVLKRLGETIELDRFHDHVRVIAGSSGGMVGAAYYVAWLRSGREFDLRNAVPLQSLWPVARHMTLRDPLKMLLPFRLGGGDRGIALEQDWTVLRNLRFADLRTAEAEGKLPSLIFSPMLVDDGRRLLISNLDLRRLSPPGQVPRAMAHTRGSALSDKGTGGEMRPYSLTATEYYKMFAEQDQGLQPDPGLLLSTAARMSASFPFISPAVNLPSDPPLRVVDAGYYDNYGVNVAAAWIGMNREWLAENCSGVLLVQIRDSMNRRERLGYPTPVTSAMGEVLKGFQFFTSVTDGILAARVSSSMFRNDAQVAALSDVFAGLTKNRAFFTTAFFENSANVTIDEDLERWPNDQQASTDPSQIATTQVAMSWYLTVAEQLAMDRAIPSDAAAEKAFGNVDQKTKRVERLNALKNEAFKTVWAPRRQAYLYLQYERAMNYERLQSLKDWWGKDHSSPAANLAITE
>NC_019892.1|WP_015247598.1|5306819_5307293_-|hypothetical-protein
MLPAIAKRQESALKQGDGPVPQPENEGPAVPDAPGWMERMAMPVASWAAPTSGEESAADHFDIPVEGDRPSAETSEAKAIPRPGPSPIPIFGLGLVGLALIGQRRRRNSQHRSSGPRSPVSRESTRLQIRQSLPHAVSRQRYQEQETGGWDGFLSCL
>NC_019892.1|WP_015247597.1|5305661_5306711_+|lectin-MOA-related-protein
MDEILVEVRNNVAQPRPARVVEPWDRKDRPQVPEPTTAQRLGITPRFSDPIPLSAIDPNVPYLIVDEYDRILCPDNYGQSYWDYMFFGKFEDYAGYVLGTQFSMNPLAGYAALHLGPPHSQVALYAYGSSTKYEYLIYGQPGYAKSPIARMKAVNSSGDHFNLRYEIAGGDMYLCCDAASWNWAYVGNTTYRRIPLTARKFYLRKADLFTLFRETWPSADINEMSFRNLDDEYELVHAAKASQIYNNSGLGNFRYVKEVFDCDDFGYVMKAAASKQAYDDNRAAGGAVVRPYALGFVWGISGPYSHVANVFVDYTGTVKILEPQSGRIVDGKDWQYDSNHKYKPYFICL
>NC_019892.1|WP_015247595.1|5304903_5305239_-|hypothetical-protein
MCPNNLVLDPENSANVTIDEDPERWPNDQQASADPSQIATTQVAMSWYLTVAEQLAMDRAIPSDAATEKAFGDVDQKTKRVERLNALKNEAFKTVWAPDARPTCTSSTSEP
>NC_019892.1|WP_015247594.1|5303497_5304139_+|hypothetical-protein
MFVERASIAQVMAFVALAAVNLGVFRALPLEVVRFPTLWVFLGAIDVVIFRKLICVRSLRAFHYTFLIVFVLAWIVMANLVVTARFHPLGLLVQWYQQITTDKINVVSLDSFDFYELWMTCFLSFALAVAIGLVAAWFESRRNWDIAACLRGALAGFGIANLLAVIDGAVWGWGVVSPVRMVGRLILVGVCVILGGVVGLSKLKSNTPGRRVP
>NC_019892.1|WP_015247605.1|5323623_5325144_+|glycosyltransferase-family-39-protein
MPAKLGGSGGLLALLLVAWCLRVVLVLRGGQCYFPDETRYFQCWGVLEHLARGELGGACDVVVGSVAHCFYTVLCCGPAVVQCGVAWLGGRPIRWVIVRDWLSVSALVLSLASVVCIGLTYAVARRAGGDRREGLAAALLMACSSSMFYYARHLLPYDASMALALLALWIGLGKHPGPARSAWAGAVAGLAFLTYYGYWLMAVAVTAIHVLGGWPSWGGVARRGLAAGLGFVAPVALVLLLAVARGSDLPASLLRFPGTVTQGDFKEGWSLPWVYLWHAEHGLLLVWGLGAPAILLFAGRASRNASGRVRGLRWLATAFSLYLVLAAGSTGMERMVVYGRLARQVVPFFCLGTACALTRLLDGRPLGRGVILGTLVLLAQAAFNFGAPLALHYPGDVLRRVEAIYGPVARGLTFEGPRLDHGIPDDPFRSHERPGAELGANYLMLNAQFLYPIEGLRAPPRGEILVRVPHPEGFFPYQYEGFGGRERALLRAGQTVMELIDTHGRP
>NC_019892.1|WP_015247606.1|5325218_5326346_-|SGNH/GDSL-hydrolase-family-protein
MTTSCRLASALLVLLTLPPGLSKAQEVQWRDAASFAIEGKGWAKTEGPFVRLPDSAKNKVSPTAWQLSKESAGICIRFVTDAAAVSVRWSLTSGSLEMPHMPATGVSGVDLYARSANGAWRFIGNGRPHKQDGNLAKFDFTDGGKPGRECLLYLPTYNGTKSLEIGVPPSAHLEAAAPRPEGRSRPIVVYGTSIVQGGCASRPGMIWTAILGRLLDRPVINLGFSSAGTMEPPVAEPLAELDAAAYVIDCIWNMSEDPALYLDHVTRLVQTIRKAHPTTPIIFVGQSQMRPEAHPTKATLGQEAAVRSLQEEGVKGLFIVPGKDLIGDDGEGTVDGVHLNDLGMDRQARCLFPIVRKAVNGPEDSDRPEDKTSAR
>NC_019892.1|WP_015247607.1|5326628_5328728_-|hypothetical-protein
MLIPSSFRMFFGLVVMAVVTTEAAAEPPLVRSAKSGAWSAAETWDQGRIPKAGDRVVIRAGHHVGYDVSSEDVIRLVQIAGTLEFARDRSTRLDAGLITITTNEEPSEDGFDCHAAMAEMKGMAESSRPALLVGRPGSPIPAEFTATIRLHYVEGMDKVSCPAVVCCGGRMEFHGAPLPQTWLKIRQTADAGGSSVYVDEWAEGWKQGDHVIVTSTRRQRDGRGVGGDFLAGAQTEERRITGLSPRDFTGGYALKLDRPLAFSHFAEGNFRAEIANLTRNVVVESADPDGVRGHTMYHRNSAGSINYAEFRHLGKRDEKGRYSIHFHLAGETMRGSSVIGASIWDSHNRWITIHGTDALVVRDNVGYKSVGHGYFLESGSEVNNVLDHNLAALVLPGKPQKDQEVPFDLNRGAGFWWANSQNSFTRNVAVECAEYGYRFDTKKTEDYDPVRSIRQPDGTVQPKDARILPFVRFEDNEAHTMKFFCLNLRGVTRPDRGLDFYSQSESLARESAEAIPEAGHPFWIRNFRGWEANWATHLGTTGVFIDGLDVFRSDVAIWRSIMDGSGFRRMTTKDMRVNDIHNPLSSGYVPSKGEADRGVFRGVSSFRDDMPPTTVITSAIREGNLVVVKGSTADTSDLKRVTVNGRPARSTRGSFAEWEIALDAPAGKPFEIAATSEDVHGHVEPRPHVVRMDGAEAPK
>NC_019892.1|WP_015247608.1|5328852_5329845_-|DUF1559-domain-containing-protein
MVYRPRHRCSLRLGFTLIELLVVIAIIAVLVGLLLPAVQAAREAARSLHCKNNLKQIALAAHNYHDINNCFPSARPSSSPQYGHMVTLLPFIEQGSLVNSFNVSVPGGFGDAANQTVANTKLSILLCPSNPVQSTCNLRKSSQTGKAYGAFITDATGKTLTGWTTDYWVNHGINATTYALISPNPTPDPILKGNTPTMAMVTDGLSTTTLFLEHAGYDRHYIKNVGMPMPDTDLTLDQPGAWGAWLGWCAFMVQGYPNYTLTTYPAGTSNAPSGTACAINCNNSQGVFGFHPAGANVAMGDGSVRMFSQSMSVANLMYSVSRNGGEIVQE
>NC_019892.1|WP_015247610.1|5330376_5331048_-|hypothetical-protein
MKRLIFAVLAIPCVALAIDPQLMPDPLYEPKIGDLCVIGFFDTQSKTCSDVEAWKDESTYQEYWKALLGNDETKRKAIEASGRMIEIKAGTRAELLKQQTYPVRDPRPDAANLRPNHGPYKNQSIWIARSDILRKAENSRPTTEATNARAVSLLKSGQNLEKRGKKASAIESYGRVMTDFPDTPEAKTAEERIKALGGEVPAKRETKAKADTSPSASTGKSPR
>NC_019892.1|WP_015247611.1|5331458_5332313_+|sensor-histidine-kinase
MTWDRLGVVSLHLKRDVWGTARFLNTLAPYWGESPDVILDLSACTFLNAEGAAILAAFVLHRQQWGRQTQIDWETVSAEIRRQLGRWELTKLFGANNHPWTDNAIPLFHQTELDGEAVEGYIGTVIRAGDNMPAMTPDLVKETNRSLCELLVNIFEHAGSPCGGLAIGQYYPHVKEVQFCVCDLGLGLARKVQQAGFAQNCCGSAIQWALEEGHSTKSGPGGLGLFMLREFVKVNGGSLRILANTGYYAQKGVNRTAQSMLTPFPGTLIQIGLLIRPDEVYTIQ
>NC_019892.1|WP_015247612.1|5332335_5332686_+|STAS-like-domain-containing-protein
MTPIRVVELIGPVCVDPEDGAVLCQQTHTALAQGACAILDFSGVRTLTSSFLNSAVSCLFANFSVDALSQRLNWTGLDSTDEKLVHLVLKNAARYYNATPDQQAAILSASNRALED
>NC_019892.1|WP_020467545.1|5332695_5333373_+|hypothetical-protein
MIPARMVKASVVDLRAGSAPLPKRGIVDANVLYIVGYDFTSSVTAGLRSPSPYQIRFYPIWWKKAVQGGVALCTTAGALAEVAHIIERTELEILWRTDPRRPELDPDMPGQDFTPKYIKTVRYHYYSQLQALRESVETTLQSIRKLVDVIPQVGQDASALDQTLVQWIPSAADFGDAAFVASAQRTGMRHVISDDADLISFEGITVYTANRSAINAAALAGKLAT
>NC_019892.1|WP_015247614.1|5333618_5334857_+|aldo/keto-reductase
MNPENQFSRRRIVQGIGAMGVGALAGGAVKGEEPGQNPLVAKDQASGVKLLPTRKLGRNGPMVPMLAMGGDMETSSAPGLINRAWASGMRYFDTAQKYGQAHEEEIYRRWFAAHPERRKDIFLVSKDYPTKKGPEELLEMIDVRLKAIGTDYIDLYFIHQLCPEVYGAESVNWGKSDVFRKVAETLKASGKVKMVGFSCHGGPEYIQAAADGGFLDALMVQYTPFYERGGAFDRALTACHEKGIGLIAMKTLRHAGNVPKRLPEFEKLGLTTHQALLQAVWSDARISAICNSVRNFDQMKSSIASAHGYQGPLEVALVDRLKDVVLASRRTMCPGCPSCDANVATTGFAFRDVSRYVTYFEQDNYGHSRDLYRALPESARTASKTDLEALRDGCAFGIDYPEIAARAVRYFS
>NC_019892.1|WP_015247615.1|5334975_5335164_+|hypothetical-protein
MFASLKAFAPAPGADEPKVEVRIVDGANSHDGESVPPGRSRRCSWTAAGSHDEANGVGNIFF

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Crispr_ID: NC_019892_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_18

5369095-5369189

Orphan

Consensus_repeat	Method
GGCAGCCCCGGAGGGGCGACCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_18

>merge|NC_019892|18|5369095-5369189|CRISPRCasFinder
GGCAGCCCCGGAGGGGCGACCGTTTCTAGCCAGGGGTGAAACCCCTGGGAAAGGTTCGACATATGAGTGCTCTGCAGCCCCGGAGGGGCGACCGT

>NC_019892|18|18|5369095-5369189|CRISPRCasFinder
GGCAGCCCCGGAGGGGCGACCGT	TTCTAGCCAGGGGTGAAACCCCTGGGAAAGGTTCGACATATGAGTGCTC
TGCAGCCCCGGAGGGGCGACCGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015247644.1\|5370947_5371937_-\|zinc-dependent-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|176229
NC_019892.1\|WP_020465464.1\|5372883_5373129_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247635.1\|5358144_5358423_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247637.1\|5359720_5360029_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247653.1\|5378180_5378567_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_026011888.1\|5372559_5372850_+\|UBP-type-zinc-finger-domain-containing-protein	unknown	unknown	gnl\|CDD\|366940
NC_019892.1\|WP_154673585.1\|5376661_5377300_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227645
NC_019892.1\|WP_015247643.1\|5368095_5368878_+\|DUF4465-domain-containing-protein	unknown	unknown	gnl\|CDD\|379679
NC_019892.1\|WP_015247640.1\|5364852_5365266_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NC_019892.1\|WP_015247639.1\|5364069_5364732_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|379193
NC_019892.1\|WP_015247647.1\|5374274_5374817_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020465468.1\|5375772_5376537_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	unknown	unknown	gnl\|CDD\|378065
NC_019892.1\|WP_015247649.1\|5375277_5375592_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015243913.1\|5362567_5363911_+\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_019892.1\|WP_015247655.1\|5379172_5379334_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_161625790.1\|5374902_5375193_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293786
NC_019892.1\|WP_015247642.1\|5367025_5368018_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015247636.1\|5358615_5358933_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247641.1\|5365397_5366462_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187652
NC_019892.1\|WP_015247638.1\|5361041_5361839_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247644.1\|5370947_5371937_-\|zinc-dependent-alcohol-dehydrogenase-family-protein	gnl\|CDD\|176229	cd08268, MDR2, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	7.02449e-175
NC_019892.1\|WP_015247638.1\|5361041_5361839_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	9.84217e-25
NC_019892.1\|WP_026011888.1\|5372559_5372850_+\|UBP-type-zinc-finger-domain-containing-protein	gnl\|CDD\|366940	pfam02148, zf-UBP, Zn-finger in ubiquitin-hydrolases and other protein.	1.80152e-09
NC_019892.1\|WP_154673585.1\|5376661_5377300_-\|hypothetical-protein	gnl\|CDD\|227645	COG5340, COG5340, Predicted transcriptional regulator [Transcription].	2.07758e-10
NC_019892.1\|WP_015247643.1\|5368095_5368878_+\|DUF4465-domain-containing-protein	gnl\|CDD\|379679	pfam14717, DUF4465, Domain of unknown function (DUF4465). A large family of uncharacterized proteins mostly from human gut bacteroides, but also some environmental and water bacteria (Planctomycetes) as well as metagenomic samples Most proteins from this family are secreted or located on the outer surface and may participate in cell-cell interactions or cell-nutrient interactions This function is supported by a solved structure of a Bacteroides ovatus homolog, which adapts a galactose binding (jelly-roll) beta barrel structure.	1.71808e-47
NC_019892.1\|WP_015247640.1\|5364852_5365266_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.68752e-31
NC_019892.1\|WP_015247639.1\|5364069_5364732_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|379193	pfam13451, zf-trcl, Probable zinc-ribbon domain. This is a probable zinc-binding domain with two CxxC sequence motifs, found in various families of bacteria.	9.17781e-14
NC_019892.1\|WP_020465468.1\|5375772_5376537_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	gnl\|CDD\|378065	pfam08843, AbiEii, Nucleotidyl transferase AbiEii toxin, Type IV TA system. This family was recently identified as belonging to the nucleotidyltransferase superfamily. AbiEii is the cognate toxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	2.01376e-14
NC_019892.1\|WP_015243913.1\|5362567_5363911_+\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.86613e-05
NC_019892.1\|WP_015247642.1\|5367025_5368018_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	3.83472e-42
NC_019892.1\|WP_015247641.1\|5365397_5366462_+\|SDR-family-oxidoreductase	gnl\|CDD\|187652	cd08948, 5beta-POR_like_SDR_a, progesterone 5-beta-reductase-like proteins (5beta-POR), atypical (a) SDRs. 5beta-POR catalyzes the reduction of progesterone to 5beta-pregnane-3,20-dione in Digitalis plants. This subgroup of atypical-extended SDRs, shares the structure of an extended SDR, but has a different glycine-rich nucleotide binding motif (GXXGXXG) and lacks the YXXXK active site motif of classical and extended SDRs. Tyr-179 and Lys 147 are present in the active site, but not in the usual SDR configuration. Given these differences, it has been proposed that this subfamily represents a new SDR class. Other atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.31705e-128
NC_019892.1\|WP_161625790.1\|5374902_5375193_-\|hypothetical-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	1.17409e-05

>NC_019892.1|WP_015247643.1|5368095_5368878_+|DUF4465-domain-containing-protein
MNRYFAMALLLASFAATADASPITTTFESFSLTSESYLNDAGPSGFFLSDGHKFNNDYNSSYDAWYGWSISNTTDTTTPGYLNQYSAITGGGAGGSDTYAVGYTYGTPAFDNLYLDPEDPDYEITNPFHPSDTTIVLAEGTSPDSIQITNTTYTYLAVRDGDPYNFGSAFDEGDYLLLDIRGYDSSGNLVGVVSFYLADYLSANPANWSIVDSWETVDLSSLAGSATLRFGIQSSQNDPTYGVNPPAYFAADNFVVTTTP
>NC_019892.1|WP_015247642.1|5367025_5368018_+|DUF1559-domain-containing-protein
MIPVSRSMLNPRKGFTLIELLVVISIIAVLIALLLPAVQAAREAARRVQCSNNLKQIGLGFHNYHQLNNAFPAGGFGGSLASDAAANSKGAQAMRLNSWGAALLPFVEQTPLFNSINQSRWYLNPENLTAGQTSLSVYLCPTNQFSSLTRPNGDTITGPSIYGRNDYSGNYGERAVRCFPGTSCPNDYSDLGDKSGAHRGVTLTPSEPINTITTITDGTTYTIVVGEAHEAEFGMWIGHKNFLDQSAPINARNGLSPGTVWASCQVAKTSRFLGKLGCDLSQEFASYHAGGAAFAFADGSARFLKESINNKVLAALLSRKGGEIVNADAL
>NC_019892.1|WP_015247641.1|5365397_5366462_+|SDR-family-oxidoreductase
MALRAVIAGVTGIVGNNLAAHLISQGWEVHGIARRPQTGIPGVRPVAADLLEPEALRASLAGINPTHVFITSWVRKATEAENCAVNGAIVRNLLAALDPSEGLRHVALVTGLKHYLGPFEAYAKAKPDTPFREEMTRLPVANFYYTQEDEVFEAARRRGFTWSVHRPHTIIGYALGNAMNMGVTLAVYATICRETGRPFVFPGSAQQWEGLTDVTDARILARHLEWAATSDAGRDQAFNIVNGDIFRWRGLWPKLAADFGIEAAPYPGHPTPLEPQLADAGPVWAEIAAKHNLAELDLGKLASAWHTDMDLGREIEVVTDMTKSRLAGFHDYQPTLGSFQDLFARLRKERIIPA
>NC_019892.1|WP_015247640.1|5364852_5365266_-|helix-turn-helix-transcriptional-regulator
MTMPKSQPIILDEACAPRRILELFSVKWTTMVLHSLHFHGGTCRTGVLARSLPGCSKKMLTQTLREMERDGLIDRKVYPVVPPMVEYSLTPLGQLFIEPIELLYAWGEKNAEALKKLSRRRTATAAQKSTKGASRKP
>NC_019892.1|WP_015247639.1|5364069_5364732_+|zinc-ribbon-domain-containing-protein
MNHNRKRREAEARERRRREALLTNSAPVDHTALDPDNYGFLLHGFLSFIERGYYLDVPFTCASCGSEEVWTAPQQKWWYEVAKGSPHSGAKLCRSCRQDARRHKGKAHPLQNTRRWCGLIRDDLEPALLAAGWHPVIGVGEPRPALLSYTQGDVLVRLRWDDSSFGSTLILERRDALDSVFRTLVKVKGNIYDMTHGTLQRRFDDFLTAARHTLGLAAKP
>NC_019892.1|WP_015243913.1|5362567_5363911_+|IS4-family-transposase
MNHDQESPAVVDLGEAVRMFHRLVPPDVLHAQKPPTLSTVFTPWVVVWLMIYQRLTCNATMATAVGELARLSADVLPDNKRAREKSFSANTGGFSRARDRLPVEMAQRAADEVSAALIAKSPPSVKGRNAFLVDGSTLSLAPTDALRKTYPPARNQHGESHWPILHLVAAHELSSGVTVRPEVGAMYGPAAIGEVPLSAGLMPRLPVGSVLIADRNFGVFAFAWLANQAGHDFVLRLTEKRFRSMVRQGKAQGKDQWELTWQPNRWERKSNPQWPADATLRVWLHEVRISEKLTLWLVSRLPDEGCELAAIYGQRQNIETDLRDLKRTLRLEEMRGRSTEMVAKELASATVAYNMANLIRRMAAARVEIAPRRLSFNRVWSLVKVLLLESLDTTDPAKIQERIDLVLRMSGQCKLANRPGRHYPREVIARRRKFPLRPRKRGLKSRK
>NC_019892.1|WP_015247638.1|5361041_5361839_+|class-I-SAM-dependent-methyltransferase
MVDRTISDVRTSYDLVADEYVRRISEELEHKPLDRQLLDRFAASVQDFGLSCDMGCGPGHVARYLDERGLRVSGVDLSPVMVEYARKLNPGIEFSCGDMRSLEIEDEALGGIAAFYSIIHIPRPEVVAALVEMKRVLRPGGLLLLTFHIGDDVVHLADWWGRQVSVDFIFFRPEEMTGFLREAGLEVEEVVERDPYPDVEHPSRRAYIFARKPRGSSQARGPSGRPLDAGTSHGLGGQTHMSIVGHTPLKGSDDTGQKEGQEPMA
>NC_019892.1|WP_015247637.1|5359720_5360029_-|hypothetical-protein
MAAERPIQETVASFLSCMFFCVNSGKTPQVNRVMTAELQATAHLVTERGLSDKEFVDSFLHPIEANIITRFGYPKSSQPFDEFAQVFKGVTGVGLAFSRGPE
>NC_019892.1|WP_015247636.1|5358615_5358933_-|hypothetical-protein
MSKRFKATLAGRAKLKSIIDPRKVSKPTIPAARENDKVCERACRANQTPAHCLRSQELNMQTGQREYCSAKLEFMRAIQEHQQSSGRLYPTWHEVLEVLKKMGLH
>NC_019892.1|WP_015247635.1|5358144_5358423_-|hypothetical-protein
MEHSIKIRIELGLTVSAKLSPVSKPDGHKATIRALLEILTMDEVHAGVAIEGKSGNVTAYVKPTQFDIGFDRKIPNIHHIEIIGMLRVEESP
>NC_019892.1|WP_015247644.1|5370947_5371937_-|zinc-dependent-alcohol-dehydrogenase-family-protein
MAKVVRFYETGGPEVLKIEEIDVPPPGKGEVQIAIKALGLNRAEVMFRTGQYISEPRFPARLGYEAAGTVAAIGPDVQGFKVGDAVSVIPGFDLNDYGFYGELANAPAPLVTHHPPSLTWVEAAAIWMQYMTAYGALIDIAGLTKGDTVVIPAASSSVGLAAIQIANKVGATPIALTRNSSKRQALLDAGAAHVIATEEQDLVKEILGLTGGKGVRVVFDPVGGPTVAALTRVMTGFGILFIYGALSTEPTPLPLFDVLVKDLTIRGYKLTEVTTDSARKERGKRFINEGLAEGSLKPVIARTFPLDQIVEAHRYLESNQQIGKVVVTV
>NC_019892.1|WP_026011888.1|5372559_5372850_+|UBP-type-zinc-finger-domain-containing-protein
MKCEHLTSLHPVAAHTPEGCEECLRTGMPWVHLRLCLICDHVSCCDISPGRHATKHSHDTHHPVVASFEPGEQWAWCYLDQAEVDVPERALPDLRG
>NC_019892.1|WP_020465464.1|5372883_5373129_+|hypothetical-protein
MSELSLRAVAFPTLDDTQVARLGHCAGAALKTYRAGQTLFQVGDRDFKFFVVSSARSRSWTIPARRRRRSRSTALGDSPGT
>NC_019892.1|WP_015247647.1|5374274_5374817_+|hypothetical-protein
MSASAFKPSTRWAISAGGSIGGGKGKVGAGVICLTLFDVQSQRFIPLTLYGASAGVGLPVGGNLSTFSPTFFGTSKPMIPDDFDGRVTVTGADLTVLVGGSAAWCTFWNVDHDPYWLDIGGLQVGVSGGISAGIYYASTSPKNARDNDGCLIAPGGDPLCGGASRMPSSSSESGNMSQAR
>NC_019892.1|WP_161625790.1|5374902_5375193_-|hypothetical-protein
MSPNSPLKSPSSPCLGAWPPNHHWACRWGRAELVKLLLERGADPVEADAEPWATLRAWGQKSGHDAVLVVLREHGYCTTAAAPLGPLRVGRPAGLT
>NC_019892.1|WP_015247649.1|5375277_5375592_+|hypothetical-protein
MQLNQQFLHRLRVMASRGAGVRAMVDEIRTELGTNDGLALVADWYFKNAFLLRLGEVRDIEGSSCLGGLAYSDEEIDRLMLPRIENTRHLWWEGPEEMNSMNRI
>NC_019892.1|WP_020465468.1|5375772_5376537_-|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein
MSSSAALVSRVAFKGGNALRFVHGNPRSTLDLDFSADDGFPDSPDDIKALMNTALRTGERQYQVKVRCQSIHRLPPGVDKTMPTYRIKACFQLPSDRYYQNIDERLASGKHLSDVIEVEISLNDALCETGDEQLSPDAKPLRVCTLNDIIAEKFRALLQQVPRKRSRPQDVFDIASMVRKHSALIDLEKVSSFLLRKSEVRGIVATKAAFNDDVKDRAAASYEAEVREFTTEFIPFQEAWAEVLTLVSHLTIPD
>NC_019892.1|WP_154673585.1|5376661_5377300_-|hypothetical-protein
MIQEANPWAVFGFVTAMTYHGLTDLVAKEVYPITSKNAGNPHRLPLGTMPDDWSEGTRLIAARRPARVGDVAVHWTQLTEEPGFGVIIGYSSGIPIYVTDVERTLLDALRMPDKSGGIAKVLQAWRSAENVDVGKLVSYTDAYGNKVLRQRVGFVLEKLGKTHSRLDEWRHGLQRGGSVKLVANNPYAETFSAEWNLSLNVPASILAIIEGT
>NC_019892.1|WP_015247653.1|5378180_5378567_+|hypothetical-protein
MSETVSVFVSGNPTIEECRNAIEKHLQILLVQRMDTDGHLFEGVISGVWVTLFDNHGLDDDCGIEFTQFPVEIDFTRYARNNSLDWNETIFFSLVVSLSERLSEQFRARCIVVKNLQQIVRSFGPAAD
>NC_019892.1|WP_015247655.1|5379172_5379334_-|hypothetical-protein
MKKYIITLTAVESQALRDFIAASKQHLFKLAVIPGGTMDQASQTPHYAATAYI

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Crispr_ID: NC_019892_19

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_19

5390560-5390665

Orphan

Consensus_repeat	Method
ACGCTTGCCAGTGGCATGGCGGTCTTTGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_19

>merge|NC_019892|19|5390560-5390665|CRISPRCasFinder
ACGCTTGCCAGTGGCATGGCGGTCTTTGCCTCGACCCGTGGTTGCGGAGGCCGTTGGCCCCTTCCTGTTCGCGAGAACGCTTGCCAGTGGCATGGCGGTCTTTGCC

>NC_019892|19|19|5390560-5390665|CRISPRCasFinder
ACGCTTGCCAGTGGCATGGCGGTCTTTGCC	TCGACCCGTGGTTGCGGAGGCCGTTGGCCCCTTCCTGTTCGCGAGA
ACGCTTGCCAGTGGCATGGCGGTCTTTGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_044147700.1\|5383307_5384387_-\|agmatinase-family-protein	unknown	unknown	gnl\|CDD\|212516
NC_019892.1\|WP_015247656.1\|5379353_5379782_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247660.1\|5385065_5386535_+\|carbohydrate-porin	unknown	unknown	gnl\|CDD\|335962
NC_019892.1\|WP_015247667.1\|5392250_5393582_-\|DUF1800-domain-containing-protein	unknown	unknown	gnl\|CDD\|378055
NC_019892.1\|WP_015247661.1\|5386599_5387559_-\|threonine/serine-dehydratase	unknown	unknown	gnl\|CDD\|181319
NC_019892.1\|WP_015247670.1\|5397300_5398884_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_019892.1\|WP_015247674.1\|5403231_5403420_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247671.1\|5399395_5401468_-\|M56-family-metallopeptidase	unknown	unknown	gnl\|CDD\|320700
NC_019892.1\|WP_015247663.1\|5387792_5388767_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247664.1\|5389174_5389765_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247675.1\|5404053_5404902_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247658.1\|5381475_5383296_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239507
NC_019892.1\|WP_081598330.1\|5391007_5392318_-\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|226587
NC_019892.1\|WP_015247672.1\|5401473_5401872_-\|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
NC_019892.1\|WP_015247665.1\|5389767_5390361_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247673.1\|5402140_5402950_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247655.1\|5379172_5379334_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020467757.1\|5396977_5397157_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247668.1\|5393620_5396635_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NC_019892.1\|WP_015247657.1\|5380066_5381347_+\|threonine/serine-exporter-family-protein	unknown	unknown	gnl\|CDD\|377697

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_044147700.1\|5383307_5384387_-\|agmatinase-family-protein	gnl\|CDD\|212516	cd09990, Agmatinase-like, Agmatinase-like family. Agmatinase subfamily currently includes metalloenzymes such as agmatinase, guanidinobutyrase, guanidopropionase, formimidoylglutamase and proclavaminate amidinohydrolase. Agmatinase (agmatine ureohydrolase; SpeB; EC=3.5.3.11) is the key enzyme in the synthesis of polyamine putrescine; it catalyzes hydrolysis of agmatine to yield putrescine and urea. This enzyme has been found in bacteria, archaea and eukaryotes, requiring divalent Mn and sometimes Zn, Co or Ca for activity. In mammals, the highest level of agmatinase mRNA was found in liver and kidney. However, catabolism of agmatine via agmatinase apparently is a not major path; it is mostly catabolized via diamine oxidase. Agmatinase has been shown to be down-regulated in tumor renal cells. Guanidinobutyrase (Gbh, EC=3.5.3.7) catalyzes hydrolysis of 4-guanidinobutanoate to yield 4-aminobutanoate and urea in arginine degradation pathway. Activity has been shown for purified enzyme from Arthrobacter sp. KUJ 8602. Additionally, guanidinobutyrase is able to hydrolyze D-arginine, 3-guanidinopropionate, 5-guanidinovaleriate and L-arginine with much less affinity, having divalent Zn ions for catalysis. Proclavaminate amidinohydrolase (Pah, EC 3.5.3.22) hydrolyzes amidinoproclavaminate to yield proclavaminate and urea in clavulanic acid biosynthesis. Activity has been shown for purified enzyme from Streptomyces clavuligerus. Clavulanic acid is the effective inhibitor of beta-lactamases. This acid is used in combination with the penicillin amoxicillin to prevent antibiotic's beta-lactam rings from hydrolysis, thus keeping the antibiotics biologically active.	3.82105e-122
NC_019892.1\|WP_015247670.1\|5397300_5398884_-\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.00605e-30
NC_019892.1\|WP_015247660.1\|5385065_5386535_+\|carbohydrate-porin	gnl\|CDD\|335962	pfam04966, OprB, Carbohydrate-selective porin, OprB family.	8.44311e-29
NC_019892.1\|WP_015247658.1\|5381475_5383296_-\|hypothetical-protein	gnl\|CDD\|239507	cd03414, CbiX_SirB_C, Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), C-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase, responsible for the chelation of Co2+ into sirohydrochlorin, an important step in the vitamin B12 biosynthetic pathway. CbiX often contains a C-terminal histidine-rich region that may be important for metal delivery and/or storage, and may also contain an iron-sulfur center. Both CbiX and SirB are found in a wide range of bacteria.	5.1873e-06
NC_019892.1\|WP_015247672.1\|5401473_5401872_-\|BlaI/MecI/CopY-family-transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	8.02766e-30
NC_019892.1\|WP_015247667.1\|5392250_5393582_-\|DUF1800-domain-containing-protein	gnl\|CDD\|378055	pfam08811, DUF1800, Protein of unknown function (DUF1800). This is a family of large bacterial proteins of unknown function.	3.63625e-103
NC_019892.1\|WP_015247661.1\|5386599_5387559_-\|threonine/serine-dehydratase	gnl\|CDD\|181319	PRK08246, PRK08246, serine/threonine dehydratase.	9.86091e-148
NC_019892.1\|WP_081598330.1\|5391007_5392318_-\|DUF1501-domain-containing-protein	gnl\|CDD\|226587	COG4102, COG4102, Uncharacterized protein conserved in bacteria [Function unknown].	6.09708e-46
NC_019892.1\|WP_015247671.1\|5399395_5401468_-\|M56-family-metallopeptidase	gnl\|CDD\|320700	cd07341, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	8.255e-43
NC_019892.1\|WP_015247668.1\|5393620_5396635_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	6.46939e-29
NC_019892.1\|WP_015247657.1\|5380066_5381347_+\|threonine/serine-exporter-family-protein	gnl\|CDD\|377697	pfam06738, ThrE, Putative threonine/serine exporter. ThrE is a family of bacterial and Archaeal proteins that catalyze the export of L-threonine from the cell. UniProtKB:Q79VD1 has been characterized as being necessary for this export. The domain exhibits 10 putative TMs and catalyzes the proton-motive-force-dependent efflux of threonine and serine.	1.06284e-41

>NC_019892.1|WP_015247665.1|5389767_5390361_-|hypothetical-protein
MKPPPMTTRQMILLVAIAAVMLGGPQVIERLHQDGESRAITHNLMAYFCGNEASLFSERATTCRSLASKGIPWNQEGEERETLRLCPHQIQEPEHGSWTEQSAGWERAAKIAGWASTRHWWTAGLYNLWGGWPTVAPFSLITLLVFSWFFLGRLDRSSTGESTRRGSKIALLLLVLCLLPWVLQDWGCLSLFLEARE
>NC_019892.1|WP_015247664.1|5389174_5389765_+|hypothetical-protein
MVETGPVPVIRRFNLGDLMILTIAVAVSLAPAVKVVSSIAESFAKLPPSGRSLWYYDDFVWWWAGVVSRVGPRSWVISGVVQLLLCLFTPLAPALVVARLRRPRPPLRLIACQPGFVACALICLALLVGMELTILRIGLVPPPVLMVIPGALVITAWSILAARRQWRRERSWVDRAGRIVGMAWIALLPWMIWSAF
>NC_019892.1|WP_015247663.1|5387792_5388767_-|hypothetical-protein
MITESIKDMLEACETGQPVFPPSVLFNEGWLLRIVLDWFAHHGGDRYPLSPKPGARWFSEPWLPSAFLPRYRGDRLAEARSHADGVLGHFSIGDPGTAGLTLQADASQLVVIEAKLFARLSTGVKNAPYFDQAARSVACIAEVLRRAGRTAESMDALALLILAPRARVDDGVFAWDAAPEAIRRKVRRRVEDYAGERDAWFHDWFEPTWRRVEVRCLSWEDIIEVIAFHRPEAGQVIDSFYGRCLHYNRPRARAAFPGRRFGSAGERGEAVSLNHPSGVTAGEPSEPKSGPKGEGVKPSTAGERPQRLVPAGFSEDDEALRRDP
>NC_019892.1|WP_015247661.1|5386599_5387559_-|threonine/serine-dehydratase
MPTTHDETVNRERIAATEPLIRPHIRRTPVIEIDGSDFGLAPMALCCKLELMQHSGSFKVRGAFANLLLRDVPMAGVVAASGGNHGAAVAYAAMKRGVPAKIFVPGISSPAKIARIRSYGADLAISGERYADALAASEAWVAKSGAMAVHAFDQAETMLGQGTLGLELAEQAPQLDTLLVAVGGGGLIGGIAAWYAGRVKVIGVEPETAPTLYRALEAGRPVDAEAGGIAADSLAPRRIGERVFPIAQRYVDRVVLVPDQAIADAQAALWQALRVVAEPGGATAFAALLSGRYQPRAGERVGFLVSGGNTIAVDFSGAR
>NC_019892.1|WP_015247660.1|5385065_5386535_+|carbohydrate-porin
MNFVGGPDPDQRPAEIDEDFMINMGWHKWGWVVLVPGVLVLLALSPTRAEAQDPVIIPGLPGANLPAGARPSPTTWPYTDLPGGRSAASTDTTESPPPAAPPYGLTGSWFGARDTLFDKGIDLRTNLSQFYQGTTSGGLRQTFPYGLKFDYFGTVEAEKLFGWEGLFINLHGESRFGESINRDVGSLVPSNFALEFPKPRGSASALTNMQVEQFLGPDFVVTFGKLNAADGVNIHPFLGGNGINRFMNEAFVLSPIYGRTIPYSTPGAGFSYLRDLDPIFTFLVLDSNGRPDTSGIGHMFSNGASLFAHLRVPVTPFGLPGHQSLEAAYTSGKFSPFSKDDYIILDQPGNHATRRSGSWVVTYGFDQFLVVDDETPTKGWGVFGNISLADQATNPVHWFLNLGAGGTSPLPGRTADSWGVGYYYLATSNVLRETLRPVSPIGNEQGFELYYNAAITSWFILTADIQAIDPGQFEARSAFLAGLRAKIDF
>NC_019892.1|WP_044147700.1|5383307_5384387_-|agmatinase-family-protein
MQAQKAEGALPSAYHEKEMRRIKELGLEPADSIQDKSDISCFQRGSSPHWSGINTFLKLPYVEDVHKVGEYDVAFVGVPFDVGCTFRTGTRFGPQGMRRISALYQKYSFEHGIDLGETLAMCDVGDIFCPANITKSHDQITKGIAHILSQGTLPMIMGGDHSIGYPIARAVAQCVEGKVGIIHLDRHVDTQEKDMDEIMHTCPWFHATNIPNCPPSNLVQLGIGGWQVPRAGVKVGRDRGTTILTVNDIEQIGIDKTIEIALEVAWKGASAVYLSFDIDSLDAGFVPGTGWPEPGGLLPREALKIINGIAKEGIAAMEVCEVSPPYDISDITSLMGVRLMMDVLGTMAKNGRIGGRLKV
>NC_019892.1|WP_015247658.1|5381475_5383296_-|hypothetical-protein
MVRPIFILTTDLRPGEAAAWASMNAQAASLQAFAERALGISTKVDLACLPARSTEDPGEYQIGRVIDRCVGDGASILFVMPAAFDLNIWQRTMLGEELGAARRRHAGVSIHHDSVDPTHALLVDCFAGQILRALDERGVAPRNAGLVLVADGQGEPATRADSYRLMRLLWEQAGLGRGEVGFVRHPQPFLPDTLDRCLSEPLDWFLLPQRQWDGELCDFARVMLDDYQRAHPETAGWRLLDPPRDHPAILAWLEQRMLRLWQEKRAREAARIPSARNEPPPAQAGVWSGADWVPAGEAQIRPRAGCVTRARDSAALAEILARVLPQAERYLVKVTWHGYAPGTYTGPQALDLLLGSLPGRAVLLEGHTSSRNVGGEQIDWDADAERHRTWVRQQDIEFLRRTGLAEVIARHGAQYLNVTEAWWDGACAPAEDVWTALGGVGLRNPELAGFVPSALMELRGIPLISFARFKGPTRLGISNLFGLIPHPLRTEWHGPDITHFASVCCDLARLYGSFFPLFGLVEAFDSAVRWDRKGLYRSRWGNYDLVLTDGLFTVSEGLVGADLLASRLQGQDVRRSGFYDVVRDQLGWSQAEAEMALPSDLQASLV
>NC_019892.1|WP_015247657.1|5380066_5381347_+|threonine/serine-exporter-family-protein
MSVTKPPAVPNQDADPALHRASDEDLIVALGRALHQVGQPAHRLESTLGRVAARLDLEIHAFSLPTGLLISFERPGDSVTTTRLLRLPLKPTNLECLRRLSIESEALACGRAAPREAIGRIKELANAPRRWGAVATVAGFLLSASAFSVFFGGGLRELGVASGLGLAVGLVALAFGRSRASSRRFELTAAAVAGFIAALADVYLGHFVHWIPLASGLVILLPGLSLVDSIEELANGHLTSGASRMAGVGIVFLALIFGVLMGINLVGLLAEDGVPGSVIPLPWWAPILALPVVALGSTFRFQARLADMPWILVGSAVAFGASRAGGHLGNPLLGPFLGALVLGMAANLYARWRDPTPQLLIVPGLALLVPGSFGLRSLESLLSGASVTGLEQGFHMFMMTIALVAGLLFSNAMVASEVNPRSPAGP
>NC_019892.1|WP_015247656.1|5379353_5379782_-|hypothetical-protein
MFETVHTLPHWHDGPRQGIADYRGRPHLFESEWRDREDLDEDTFLLMPIDAATFALALEDWAIWRRWEMAFHQGKTTQETHPALPEDRGRHENLERLLDGRLTVDPARAVRSSAEFRARHTPGWSGCGWRPLEVRWSAPPGD
>NC_019892.1|WP_015247655.1|5379172_5379334_-|hypothetical-protein
MKKYIITLTAVESQALRDFIAASKQHLFKLAVIPGGTMDQASQTPHYAATAYI
>NC_019892.1|WP_081598330.1|5391007_5392318_-|DUF1501-domain-containing-protein
MRWAPPGRPSSDYWLHPRRRGFDLFSQGVETVITRRELLASGLRNSALIALAPTLPGFLARTAHAAGPEKEGRILVVLQLEGGNDGINTVVPFQDDGYAKYRKALRLPRERLIKVNSEVGLHPAMGDAGKLLESGRLAIVPGVGYSNPSRSHFRSMAIWQSARLDEGDHTGQGWVGRGLDEGSATRDGTPAAILIGPNDPPPAIRGRRSVCTAMDRLNDYALSHKKAEAEAKPISPPAATEDDLGQFLRRSLLDAYTTADRLEAIAGAGDGRASYPESELARRLRLTAQLIKAGLGTRVYYLEQGGYDTHGQQLPRHAPLLAELSTSLRAFLDDLAASQLADRVLVLAFSEFGRRVAENGSLGTDHGTAGPVLLAGPCVRPGLHGAYPSLTDLADGDLKMAVDFRRVYATVLESWLGLASEKALGGTFEPLPLLHG
>NC_019892.1|WP_015247667.1|5392250_5393582_-|DUF1800-domain-containing-protein
MRLRSGDPWASYVPDEATPWNLRRVVHLHRRAGFAATWDEIQRDLGDGPEASIDRLLEGKSRSYGVPENFAAFADRLAERAMAAPEPNRLKGWWVYRMLFGPDPLTERLTLMWHNHFATSNLKVDDLALMWRQNETLRSLGRAPFGRLLHAMLRDPALLVWLDAPENTQGHPNENLARELLELFTLGIGPYTEDDVKQAARALTGWRIVEDEARLIPGRYDPGAKTILGRTGTLDADGLAALLLDHPATSRRLAWRLGHEFFGEGAVDGPALEALGEGLRAHDLDIGWGVATVLRSRLFFDAPNLGRRIASPIDCLLGAVRALEMLDPAPSPPMLADWCGRLGQSLFYPPNVGGWPGGRSWITTRSALGRANFAAALIGIDPVGLGTSFDPIALAARHGQGRNPSFFSRLLLGAEGPEVPLDALGPARQALVRLLASPEAQRI
>NC_019892.1|WP_015247668.1|5393620_5396635_-|sigma-70-family-RNA-polymerase-sigma-factor
MPSVPQQIDRLFAEGTLTGLSDAELLGRFASGRDAMAFDALVARHGPMVLGVCRGLLNDPNDAEDAFQATFLILVRKAGTFRGPVALGGWLYLTARRVAIRANVAAARRRAYERRAAQMAQMTSEPGGSTRDELLSILHEEIARLPKKSRLAVVLCDLQGTPQDQASAELRLSERTLRRRLSEGRERLRARLAGRGLGQDQAMLAALCLREARITVPTAWRSATVRAALAAFEPAAAAGTVSAAAMALTREVSRTMLLQKLTLASAVLATSCLLAWGASAALLPPEPEVTNQGAAKAPAPAPAAPKAAESAVPPPGSDLAASAGMHPVRGQVLDPDGKPVPDAKVYVRHYAEIRWNEIDPMAARQKGRVAATDAEGRFHFELDKGASDGSYNSGEIGWHKAQIAVTAPGFAPAWIEAGDTAKQGEMALRLVRDDVPVLGRVLDSQGRPVAGVVVRIRAICEVQEGVDLDAMLASGAMDENIDNRSRYYGNPLGATTPAWQADPSPLWPGDRNTWTTDGDGRFEVRGVGRDRIARLEFHGGGVADGTLDVIARPAKASPKARPRPNLRKEVGLEGRDATFLGYYPQGTQLVGATFDYIAGPTKPIVGVVRLKGSGKPVEGAIVRGADPGTHTAVTARTDAEGRFRLDGVPKGDYYQIKLDPRPGIDPFFRHAEIIDDTEGLKPIEASVEVSPGVIVTGRLVDKATGRVIPPADVEYNKAPDNLATGSALAFSRLADGAFGLTVPPGRGMIAGAAAAEGKDDPYVGASLKAADRKQESDEKFYKFKTVGYHTYRFIDIPADSGPVAVDLELTRGLSRAGRLTDPDGRPVVGARAYGLSARDWSGTGRSQPLDAETFEVGGLESGHPRLLVFTHGARRLVGAAVLEEEDLKSNTPLEVKLVPSGAIKGRLLDDDGLPWAGARLDVTMFDPDRPPGFACSFGEPVTVDAQGHFLVDAFVPGVETEVMIIAPKGARGLLDGGNALRKPALKPGEVRDLGDVKAKKIPQQ
>NC_019892.1|WP_020467757.1|5396977_5397157_+|hypothetical-protein
MATRLPTSDEINVFDPILREGILKMLENFERYGFGGEVYGDAYGDVAGRYRVLLSRLDG
>NC_019892.1|WP_015247670.1|5397300_5398884_-|serine-hydrolase
MPMARRRFVQIAATAPLFASRPVLGAEPSADDSLRSNIRLNAGLLGLPGFVAGVVREGKLSLVQADGFADLESRTPMRQDHIFYVASLTKTFTAVMMMQYVQEKKISLDDYLLDYPFLSVGFTADRLFDPNVTLKHVLSHTSEGKPGDNFVYNGGRYNFVYGVFEKISGNTNNYKSHVNEFNKRIKEPLGLTSTLPGHPPDAKDLRIPRIVTSYALDGGRKTLKKDAGVSGATNLYPGTGLLSTVDDLAKYMIALDENRLITSESYAHITTPYILNDGRLSQYGLGWSTQKVGGHAVHWHYGFDDPYSALLVRLPEKKTSFIFLSNTGAACAPFLLGWGANVLTSSFAVAFLDSELPGVLSDADRDYSRMFLTHYTEGALGRNPGEAKRLLGKLRSTEPARFRKNDRVMISILSDLSNPAFSEEMDSLVAAYRGSGDFHPDISLAIANYYGKTGKPAKRDVFLRQIADHMGYEGGATRDACVKLGAELLRSGKTEEGRKYLWRVVRDAQTKGEKVESQERLVQALKP
>NC_019892.1|WP_015247671.1|5399395_5401468_-|M56-family-metallopeptidase
MPMLTGMGLAITIDVLIRVSFVLAVSLMLAYTTRWNAALRHAILVAGLAAVFIVPGATLAMRGLPVPRWQLGWLSRAGIDGPAEIALVSPQPPNEPQYRPARRNQPAPAIVRTRRDEARLDPGHGASAQSDKPSLGPRAWSRWNALYGRLMASCLLWTLLSGAIVKVIGLGLSLVRLRRIVARAHPVTGDHILSVLELIQGRIPMRQPPRLLESAEVSSPVAAGIIGNYVLLPTGWAGNLLLGETLAVLGHESAHLARRDHHVVIFQELLASLLWFHPLVHRLNRMLNRVREELCDNYAISLVDRASYCEALLHLAVGRPGASLRGATSMWPGRWSLEDRVRGILDERRPTDTRISNVARSATAICSLAMCGFIALPQLTASPPNDRFVTVADGDSPPRAKASLVAHEMTRSITRAFPVTGEKMLRFENLAGRVELVPGKRPTVEVEATVRVGGLAEGDVRRLIDEIGWVEVPAKDGGSQWGLSFPAEDYPTIWYPVSGEAKADSDTVHYLGHEVRIANRRGDSTPSVEFDLRISLPPGVHVAVDNAVGPIGGKSVDSPLKLSTRHGAIKLGDVRAPIDAATKFGDVLISRLDADAVVQTGSGGIELSRVTQGHVALSTGSGHCRVVLPPESGFRLHYSGTRPLELVGGGASRLSALSGDRRSEMLSRGTGGPSITVTSDTGDTVIEAGP
>NC_019892.1|WP_015247672.1|5401473_5401872_-|BlaI/MecI/CopY-family-transcriptional-regulator
MNLPEEALSPSQLEIMEIIWDKGEVAAVEVRELLASGRELARETVRTMLERMEAKGWLKHRVVGRTFFYSAAVPRGATAGQKVIELIDTVCGGSPERLMTALLDYRGLTAEEAVRIETLIKQARDRKPGQRS
>NC_019892.1|WP_015247673.1|5402140_5402950_+|hypothetical-protein
MDTMDLLTKFARIGVRVKVADRSTRRFRPPARVLSLDVQADRDGEFFEVVSPGGTSSEVAVIDVQPADRHLLLLVREGGEKHKFLCGHDERHWFVAAVPENAPVGTVRQAKEALKPPEVQVAQGRQGLRAEARNRRKNAAYRRQGEWFFLPVPGFTVDEALVLHNEPLRRGNGGKPHWVESCYRTGGETVHVCSRHPNGVTPSQHEKILANNPKAKGWNWQTMRRNPGVYVRGSVRHADHKTIVLHGWHRVLMNTEGQSSAMRNVAFLD
>NC_019892.1|WP_015247674.1|5403231_5403420_+|hypothetical-protein
MIPLDIGPPLKEKGIDCLKYASKDESGHVIAESLGGPGGQSFLFPISRLANDKMQGLEQCLK
>NC_019892.1|WP_015247675.1|5404053_5404902_+|hypothetical-protein
MTFFAKVSFYGKDASLLPHQATLNPNVLLYGEVIGFASWLMDKDWLLTLIKVTKSGSAQTADQTSFVGGRPKLPPSCPLPTCKLCGEIQSFFFQVAFPEIHPWAGRTLAVFQCTSCWKNSYHVPLICREIFPTMTTNSLLPGDDIPDDLLDLVQIRHRFLVFPTAEGVVRGDYPERVRYRPISFELAFARESTTKSKIGGQPGWIGGDDEFPGKYMGQPLIFLMQWRGEFQFKLTADAPPPYGELPEFQDTREYLLCLGNQVYFFGNDTDGKSNIYLCDQRV

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Crispr_ID: NC_019892_20

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_20

5455337-5455437

Orphan

Consensus_repeat	Method
TAACGGTCGCCCCTTCGGGGCTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_20

>merge|NC_019892|20|5455337-5455437|CRISPRCasFinder
TAACGGTCGCCCCTTCGGGGCTGCGATTCATGCTCATTTGAGTTTATCCTATTTCCAGGGGTTTCACCCCTGGCTATTCACGGTCGCCCCTTCGGGGCTGC

>NC_019892|20|20|5455337-5455437|CRISPRCasFinder
TAACGGTCGCCCCTTCGGGGCTGC	GATTCATGCTCATTTGAGTTTATCCTATTTCCAGGGGTTTCACCCCTGGCTAT
TCACGGTCGCCCCTTCGGGGCTGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015247715.1\|5460253_5461447_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247713.1\|5458377_5459538_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247704.1\|5444846_5446199_-\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_019892.1\|WP_015247702.1\|5441843_5443004_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247701.1\|5439121_5439853_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_020467179.1\|5465476_5466862_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133029
NC_019892.1\|WP_015250457.1\|5453723_5455109_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|373239
NC_019892.1\|WP_015247716.1\|5461737_5462886_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247708.1\|5452292_5453501_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NC_019892.1\|WP_015243913.1\|5440057_5441401_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_019892.1\|WP_015247712.1\|5457335_5458352_-\|phosphotransferase	unknown	unknown	gnl\|CDD\|270703
NC_019892.1\|WP_015247719.1\|5466879_5468661_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_019892.1\|WP_020467178.1\|5462885_5465402_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133029
NC_019892.1\|WP_015247710.1\|5455486_5455936_-\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl\|CDD\|227348
NC_019892.1\|WP_015247706.1\|5448303_5449998_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247714.1\|5459534_5460257_-\|ChbG/HpnK-family-deacetylase	unknown	unknown	gnl\|CDD\|212114
NC_019892.1\|WP_015247707.1\|5449994_5452010_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015247703.1\|5443007_5444885_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|276809
NC_019892.1\|WP_015247711.1\|5455964_5456951_-\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|224012
NC_019892.1\|WP_044147244.1\|5446240_5447956_-\|DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|239569

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015247704.1\|5444846_5446199_-\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	1.05396e-52
NC_019892.1\|WP_020467179.1\|5465476_5466862_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	1.19045e-41
NC_019892.1\|WP_015250457.1\|5453723_5455109_-\|IS4-family-transposase	gnl\|CDD\|373239	pfam14706, Tnp_DNA_bind, Transposase DNA-binding. This domain occurs at the C-terminus of transposases including E. coli tnpA. TnpA encodes a transposase and an inhibitor protein, the inhibitor only differs from the transposase by the absence of the N-terminal 55 amino acids, which includes most of this domain. This domain consists of alpha helices and turns, and functions as a DNA-binding domain.	3.63325e-18
NC_019892.1\|WP_015247708.1\|5452292_5453501_+\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	9.95653e-56
NC_019892.1\|WP_015243913.1\|5440057_5441401_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.86613e-05
NC_019892.1\|WP_015247712.1\|5457335_5458352_-\|phosphotransferase	gnl\|CDD\|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	9.56071e-07
NC_019892.1\|WP_015247719.1\|5466879_5468661_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	4.6726e-166
NC_019892.1\|WP_020467178.1\|5462885_5465402_-\|glycosyltransferase	gnl\|CDD\|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	3.82107e-51
NC_019892.1\|WP_015247710.1\|5455486_5455936_-\|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl\|CDD\|227348	COG5015, COG5015, Uncharacterized conserved protein [Function unknown].	9.22439e-14
NC_019892.1\|WP_015247714.1\|5459534_5460257_-\|ChbG/HpnK-family-deacetylase	gnl\|CDD\|212114	cd10803, YdjC_EF3048_like, Enterococcus faecalis EF3048 and similar proteins. This subfamily is represented by a putative cellobiose-phosphate cleavage protein EF3048 from Enterococcus faecalis v583. It is similar to Escherichia coli YdjC, a hypothetical protein encoded by the celG gene. EF3048 might function as a homodimer. Each of the monomers consists of a (beta/alpha)-barrel fold that forms an active homodimer. The molecular function of the EF3048 is unclear.	1.04642e-49
NC_019892.1\|WP_015247703.1\|5443007_5444885_+\|AAA-family-ATPase	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.43929e-06
NC_019892.1\|WP_015247711.1\|5455964_5456951_-\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|224012	COG1087, GalE, UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane].	0
NC_019892.1\|WP_044147244.1\|5446240_5447956_-\|DNA-polymerase	gnl\|CDD\|239569	cd03487, RT_Bac_retron_II, RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA branches out from a small ssRNA molecule via a 2'-5'phosphodiester linkage. Bacterial retron RTs produce cDNA corresponding to only a small portion of the retron genome.	3.39821e-80

>NC_019892.1|WP_015250457.1|5453723_5455109_-|IS4-family-transposase
MSPTLTDPEAWAQANFAGADLGDKRRETRLIRLATQIAVDSSASLPKATGNWDDLRAAYRLLDSSAVNFRAIAEPHWRSIRETSPEMALILDDTTEIDFGCTRQIQGVGPVGTGTGQGFMIHSGLMVSHKDEVVYGLAGQILFHRKPVPKGESRTQRRKRDRESEVWGKLIELIGSPPQNTRWVHVMDRGSDDFEVYCRAQRQGVDWVGRVKSLHRRVQGADGLERPLQEELESAPQAGCFTLKLRARPGLSARTAKLTVTFVRATMLVPRQPADSLKGLDPQPIAQYVVCVREIDPPASVKEPIEWVLYTSLEVACLEDALQIISYYEKRWLIEEWHKALKSGCSVADHQLKASHRLEALTGLLSVVAVRLLQLKGIARSEPERPAIEVAPPKYVAVLRAFRRATEVLPWGAYQFFRELAKLGGFLGRKGDGEPGWQTIWRGWMKLQAMVQGAELDLRLE
>NC_019892.1|WP_015247708.1|5452292_5453501_+|ABC-transporter-permease
MLANVQNALEQLWSHKMRSILTVLGIVIAVTSTITVVGVIQGFTGYVSEFLQGLGTNAMWVWPQRPAGEAGKRLGRIELDERDLAAVEAGCSALRRISPLIRRPTVAVRYGREELSIPLEGTAAEYHAIRNFPVGSGRPFAVVDVERAHHVCVVGREVLRKLNVDEGLVGQTILLDGQRFRVIGVLEEKGSFLGDNQDNIILIPYTIALKMYPASRHKLAFTAQAVSEQGVPEARSQIVNLLRRRHGLAAFQPNDFNVMTQDEILETFNNLSLVATAVLAGIVGISLLVGGIGIMNVMLVSVTERTREIGLRKAVGARRRDVLVQFLTEAVTLSVAGGGLGIALGHAFCAIASLHPQMVDVVVPWWAVVLGFGISGSTGVVFGLVPAVKAALLNPIDALRHE
>NC_019892.1|WP_015247707.1|5449994_5452010_-|hypothetical-protein
MAQKTGGNAGDWLMVQELFERGDPAFVEALRAFYDAEVLATFAPRWFADRRPEARRLLFDYLDRPLNAYRHEALVKRLFKLAEAAGDDALMARFLVAFDRSIRRAVGKQVRFETQEVDNESDANALTDSWRDRGYESVSVWRNWRQRYQVSGRWTEPCLISPRDTTMPRGALKETYDPYSWNPKLGRYQTFAVPDWVFALKLDPRQFRQGEPFPAAQRNGLARYRLFSVATRHYLRRRVWRYFRRLGRNAPERYLPAVKEALLQYRDADVANGLALIDNWSLTHILFRFSPAIVPDERGWRVAPGHSLAELEPAPRYKALWASQPRAFVDLLVLGRCRPVRGWAIRTIRRNPTAILAVFPLEERLALLEDDDPEVVGLAADLIRDDPRLADVPASRWLTLLETASPAALDILAGLVERLVRPDQVTLAEAVRLASARPLPVARLGLDWLRTKTPHDESECRTLLDLLEAGADPLRGEILGWLRQTLANSPGLKPDWILQWLDSRHEDVRAEGWRWLESDATARDDVAIWQRLLESPYDDIRLALVAALDERTRQGDAVHLKPGRLDPDLLRLLWASVLLNIHRGHRAKPQVVRQLFRQAEAHPGDLPRLLPLLAVALRSVRGPEWQAGLSAVVRLAEHDEASAALVSQAFPELQLTTAKPGPSRNQSKESR
>NC_019892.1|WP_015247706.1|5448303_5449998_-|hypothetical-protein
MNLTLAYRGRSAIVSSPGGLAVSLAPNLRRDRVAFDAAFLQPLRFREAIGALHDVVVSDHRYHAKDNSAYENYLAERNQREAEIRRTATSRTRTAILKESTGVDPAAIAAFETDYRRLRNQYWGARQKYSNYLSRHDPELWRLLVPCDPVVTVAPDCLFFECFSVDESSYGCLTVDRGAFSGERDVALGTTNVDYSWSLYEHFQTLRSYRETRFLVDPGGIEVKAGEGPGYREEKIDLPPSWLRGFMQIQAAMSLPMRRVAISREGLYSVLAFLKRHRASRSPRAVRFELIPGQPVAIVLEPWERRIVLHSLPYDGPRSEVIRVWGRDRLRLLARLLPLMDEAEVYLLGNGLPSFWSVRMGEMRLLLGLSGWTANDWTGSGALDQLAPPAEPSDALLGDIAAAFEDSPAKTFDQIRQRTGAAPAYVAAGLNRLALMGQLIHDLHAGLYRWRQIMPVALALDAIGPENAETAAARELVSHGKVKVTRDDRRDDGLRILEGEVPDRPVSLLLDADGRMLRGKCTCSHHFTGGLRRGPCRHLQALRDGSRTAQPLRSLDAWFAALGI
>NC_019892.1|WP_044147244.1|5446240_5447956_-|DNA-polymerase
MNLFHRLLRFLFGYEPPARSASQPRPTPAPAPAPEPPTTPDAIAATLTEAFGKTAETTAPALLPDATADPYFAVTADVQSTATNQGKGNGKSSLGLEANAYLPISREEIKKTAKGIDRFGNPWFGRRDLIPPTDDPRTNLIDRAMVTQGLLSPTQLHEIHDVGARMDQIRPSLAAIESRAAVDGAAAVAADREARVLLKARKKAEAAQRKQERIDQVAHRKATDIVFLGRGVSAGLNDRQSDLDALTGAGLPLLSTPADLAAALSLSISKLRWLAFHTEAATRTHYVQFTVPKKSGGLRTLSAPHRTLAEAQRWIFQEIVAKLPVESAAHGFVAGRSIVSNAEAHCRRAVVVNMDLEAFFPSIGFPRVRRVFRKLGYSPAVATILALLTTECPRRTVVYGGTTYHVATGPRGLPQGACTSPGLSNQVAIRLDRRLSGLARKFDLSYTRYADDLTLSGDATLEAKVGYLMARLRHIAGEEGFAVNEAKSRVLRQATAQTVTGLVVNDRPGVRRAEVRRLRAILHRAKSEGLASQNRDGHPNFLAWLHGKIAFVAMARPELGAALRAELDSLL
>NC_019892.1|WP_015247704.1|5444846_5446199_-|serine-hydrolase
MRVPHPLLWPVVTMAASLLASLASAHEPENNHAPATEPLVVATGIADVRLASFDRLMTKFLTENKLPGASLAVARNGQLVYARGFGLGDVEAKTPVEPDSLFRIASISKPITAAAVLQLIERGKLKLDAPLVDLLDVRHEGKPVPPGDPRLKDVTVRHLLQHRGGWDRDKSFDPMFRSVKFANELGTMPPATSWQVITAMWSRPLDFAPGERNSYSNYGYCLLGRIIEQVSGMPYEAYVRKEILEPLAIDSMRIGKTLIEERAPGEVRYVMGESRKKKQGPAVLGPSLGEPIAMPYGGWYLEAMDAHGAWLASAPALVRFASAFDAPQFGTILNESSIQTMFTRPEGRAGHKADGTPTTVYYACGWNVRTDQPGGGMNTWHGGYLDGSASLLVRRHDGLTWAVLFNSDTGSNGKSAAVTIDPLIHQAANAVKEWPIKDLFLSKITSRKHE
>NC_019892.1|WP_015247703.1|5443007_5444885_+|AAA-family-ATPase
MAGNDFIWRFTPSRTEPRLLEEIFVQRESLLADLLERISESVLTDNKHQILLIGPRGIGKTHLIALMHHRVTQDPALSDKVRIAWLLEDETITSFVQLMKRFYELLAEEYPAEFPLNWLEDLLDLPPARILKALETTLVDKFRDKVLLLFVENLDLIFEGLGDEGQKKWRAFLQTHPFMSVVATSQRIFRSIQSREQPFFGFFATNHLQPLHTSDAVELLRRIGRHREQADLVEFLATPEGRSRVRALHHIAGGNHRISIVMSGFLTRESLDDLVEPFERMADAMTPYYQERMRWLSAQQRQIVEYLCSREDTCTPKEIARHLLAAENTVSSQLNKLLKLGYVLRSPRGRESLYELAEPLMRLASEVKEKRRKPLRLLVNFLRIWYRPEVLPQLLVKAGTFDLTYQYEEFQNPEAALACYDKFLETDPQNETALTLKGNLLSRLGRHEAAFHCYEQGLEFGSAEQRHGFSRCEPMFALRCWERGFEALAEAFDRFPGDRNHDVEMIIDLMMRLSEGAEELQQHVSRLIAIYCEADALDFLGSGLLRSLRRIDVGRIGLETLKNWREAWLKWGGGHPELGIPLRIFRVGIEYFLQGDEKVLLDLVTPERTILRQLLMLSRSNLAEE
>NC_019892.1|WP_015247702.1|5441843_5443004_+|hypothetical-protein
MKANPGGVVDPRNVYGRDRLISGIWDQLDRLCLLMNAERRIGKTSVLRKMKHEPAPGWFPVFLDLETFHSAEEFAIAVYGQVQTYLNTWKKAANAARKIYEDHEFGDFKRTSGSRPWKALLAAAVRDLVSEKQDVRLVFLWDELPYMIDHIRRANGEQAAVEVLDTLRSLRQEYTDLRMVFSGSIGLHHVLESIRDGKMSSEPVNDMYAIEVPPLDMEDAIKLAGDLIQGENLSASDPGQAAGVIAEESDCFPFYIHHVVAGLRQAGRSAEQSVIRDLVQRQLVDANDPWDLGHYRRRIPAYYKKDATAQLVGLILDTLATAPDPLTVAQLQSGVNNRSTAFDSRDELVRVLRLMERDHYLLREPDGRIRFRFPLIRRWWALDRGI
>NC_019892.1|WP_015243913.1|5440057_5441401_-|IS4-family-transposase
MNHDQESPAVVDLGEAVRMFHRLVPPDVLHAQKPPTLSTVFTPWVVVWLMIYQRLTCNATMATAVGELARLSADVLPDNKRAREKSFSANTGGFSRARDRLPVEMAQRAADEVSAALIAKSPPSVKGRNAFLVDGSTLSLAPTDALRKTYPPARNQHGESHWPILHLVAAHELSSGVTVRPEVGAMYGPAAIGEVPLSAGLMPRLPVGSVLIADRNFGVFAFAWLANQAGHDFVLRLTEKRFRSMVRQGKAQGKDQWELTWQPNRWERKSNPQWPADATLRVWLHEVRISEKLTLWLVSRLPDEGCELAAIYGQRQNIETDLRDLKRTLRLEEMRGRSTEMVAKELASATVAYNMANLIRRMAAARVEIAPRRLSFNRVWSLVKVLLLESLDTTDPAKIQERIDLVLRMSGQCKLANRPGRHYPREVIARRRKFPLRPRKRGLKSRK
>NC_019892.1|WP_015247701.1|5439121_5439853_-|hypothetical-protein
MSDKGIPLSRMMKFTALIALNCALVKANPSIPQSPLLLFALVMLDIVLVQAVILGHPLRAFHYTFLVVGFAASLAITEVAFMPTTTGKRGSLHLLETLIRRQESIANTISLNQQLSQYLEIAERGVTNTLGLLVAWVVGLSVARQVRRRRGLEPGRRIRHIGSFFQGALIGLGIFTSIVCAINFCGLPPNAPRQGLFLYAFLLSLAILPLLGGFAVMYLNQRRDPSSAADQGEPAGPSQISAS
>NC_019892.1|WP_015247710.1|5455486_5455936_-|pyridoxamine-5'-phosphate-oxidase-family-protein
MTKPTPEPIDPKQLVELALGVIKAARFPMLATIDGDQPRVRPVSPVRTVGFTVYVANLRSYHKTTEIAANPNVELCYLDDHHDQVRITGLAEVVTERELLQSIWDANPLLRQYLGSIDNPQFLLYRIRPVRVRHMKEWALDYHEVSFEP
>NC_019892.1|WP_015247711.1|5455964_5456951_-|UDP-glucose-4-epimerase-GalE
MAILVVGGAGYIGSHTVRELEKAGQQVWVFDNLSQGHAEAARGDRLIRGDLLDRAALDDALRGRDIDAVMHFAAFASVPESVADPAKYYRNNVVGTLNLLDAMLAAGVTRIVFSSTAAVYGVPDVVPISEESPTRPINPYGFTKLAIERALADYAHAYGLGYAVLRYFNACGASSDATIGEDHTPETHLIPIILQVALGQRESLSIFGTNYPTPDGTCIRDYIHVEDLADAHVRALAKIEPGRGLTYNVGTGVGASVRGVLDAALQITGRPIPAVEFPRRPGDPPALVASSDALQRDLGWSPRYPKIADVIASAWKWHSTHPNGYRSR
>NC_019892.1|WP_015247712.1|5457335_5458352_-|phosphotransferase
MATDDAGGHLDLTELPIVLAEVLQQSLGRPVRMEQLSTRPSPNWTSSFLLEIDAVIEGGETLRLLLKSSSRSDLHETARRVKPSFLHDPRREPAVYRELLDAANLGTAKYYGESLRRCWLFLERVPGVALFQIGDLSAWREAAQWLARLHLGFAGEDAPRSQTVPLLCYDAHHFCTWLERARTFQGERARGPIWDRLEQGFLNALDRLSAMSTTLIHGEFYASNVLIETKQNSRRVCAVDWETAGIGPGLIDLAALTSGSWPAEDRFKMAESYRMALAGSAPLPDQFSADLDACRLLLAVKWLGWSADWSPPADQRQDWLGEAVALADAMVPKAGGRK
>NC_019892.1|WP_015247713.1|5458377_5459538_-|hypothetical-protein
MKATRATILVSGMIAGHPNQGGASWVVLQYALGLRKLGHDVLLVEPIEATALRPAGSSLAESDNAAFFRRVVRSLGLERSSALLLAGTRQTVGVSYDRLERETRRADLLVNVSGMLTDPGLIGSIPRRVYIDVDPAFNQLWQEKHGIDMRYEGHTLFMTVGRAVGRPGCDVPTCGREWVATWPPVVLPLWPTAGLIRHHGFTTVANWRGYGSIEHGGLLFGQKAHTFRTLFDLPARARAPFMPALAIHPGEVPDLEALAANGWQILDPARLANTPARFRKFVQQSEAEFSTAKSGYVLSRCGWFSDRTACYLASGRPAIVQETGFQGEIPVGEGLFTFKTVDEAVEAVNAVRGDYPRHARAARHIAEEYLDSDKVLDRLLNLAFAT
>NC_019892.1|WP_015247714.1|5459534_5460257_-|ChbG/HpnK-family-deacetylase
MTRFLIVNADDFGLSDGVNQGVIRAYEEGLVTSASLMTGGAAAEDAAAYARLNPELSVGLHLDFGEWLFRDGDWHQTRQVVPLPNDRAASASEAARQIDRFLQIVGRPPTHLDSHQHAHRDEPLRSVVLEAAQRWGIPVRHAHPEVRYCGRFYGQTSRGEPFPQAITAENLVGILNGLPEGWTELACHPGLGNDAPAVYRTERADEVAALCAPSVRSSLAETGIALRSFHDVRECLRMDR
>NC_019892.1|WP_015247715.1|5460253_5461447_-|hypothetical-protein
MSIVVVAGALANKPRNGGNAWAVLSWALGLRALGFEVAFVEQIRRDCCVDAAGQPCPFEDSENLAFFRKTTEQLGLDGLSALICEDDERSFGLTPTDLADLGRSAKALVNITGHWNLAPLFDSVGCRVYIDFDPGYTQFWHAAGNAGTRLARHDYYYTIGENIGRSGCEIPVNGIAWRPIRQPVTLEDWPTCPSLGFDRFTTIASWRGAYGPVSHKGTTFGLKVHEFRKFLEMPRQTALAFEIALDIHPADFKDRDALLEQGWNVVDPHRTTGGLDEFRDYVSTSGAEFSAAQGVYVATESGWFSDRTVRYLASGRPTLVQDTGFSRNLPVGEGLIPFRTLAEAVAGAERIARDPACHAQAARAIAESHFDSQHVLGRFCEEIGLHPQPKKGKGATR
>NC_019892.1|WP_015247716.1|5461737_5462886_-|hypothetical-protein
MRDTIVIAGAVARRPGCGGHAWVFLQYLLGFRRLGWDVLFLDELEIDPAGDSHAPHLTASALELAGLMERFGLGNDYSLNIGRGTRTVGLARADVLERVGRSAFLLNVMGYLADEEILARAPRRVFLDIDPGFGQIWKAEGLADIFQGHDDFVTIGENIGRPECVIPTCGLHWLTTPQPVVLEQWPSHEDEPGRCWSSVMSWRGAFGPLTYQGQTYGLRPPEFRKFATLPRQSGRRFELALDIHPDEVKDLAMLAENHWSLVNPAQVAGDPWRYRTHIQGSRAEFMVAKNLYVKTQGGWLSDRSLCYLASGRPVLAQDTGIQSLYPTGLGLLTFSDLDEATAGVEIVERDHAKQARGARALAEEFFDSDRVLGRLLNKLGIA
>NC_019892.1|WP_020467178.1|5462885_5465402_-|glycosyltransferase
MAGEFIPAGKRILIVSKGDEDLLRVADRETAHFPQAEGGGYAGHHPGDSEEAVGHLENLRAQGWEYLILPATSLWWLSHYTEFESHLRTHHECVCTNEAGIIFRLSGSTSLARNGRSSRASAFSRNGYSPSPPPKAANVMEEYARIKLRQFLAGPGRLRFPKVDEPVVSIVIPTYQQAHYTLLGLESLLVADDDVPFEVIVVDNASTDDTEALLSRVENIQVANNDCNLGFGEACNRGAKMARGEFVCFLNNDTLGTPGWLSVLVETARSEPRCGGVGPKLVHPSGRLQEAGGILWRDGSNLGYGRNANPTDPEYDYVRDVDYCSGACFLMRKDLFLALGGFDPRYAPAYCEDTDLCMAIREADLRVVYQPRACVFHIEFGSSEAGHAVELQLRNRARFRAKWRLKLRQYPAAGSGEEWLARDRREGRRILVADDRVPDAGLGSGFPRARTLLESLASLGYIVTFLPLNNVTALEPATSELQQLGIEVLHGVKNIRERLSQRHDLYDAILVSRPHNAHWIPVIKEFNPEAAVIYDAEAVFCLRDALQAEVEGKNPLPPLESKRRLRKELSLADDANAVIAVSEQERALFTKHNPDIPVLVWGASILTRNASPSFDARRDYLFLGSLATPPNADALRLLLDAIFPAIRERSNARLTVVGAPVPASTTAADAPGSVVLTGYVNDVSPFFDRARVFLAPHRFAAGVPYKVIEAMAAGLPCVLSPLLAQQLEVTDGAEALVGDGVDDFRLKALRLHEDKALWLRIQQNALRLIRDRFDPAKMREALGNCIEGAFESHFGHASHNRRPAQIVAAPGTTQTIRPPQSPSIPLVDDPLFQARATI
>NC_019892.1|WP_020467179.1|5465476_5466862_-|glycosyltransferase-family-2-protein
MIVDDDLLSVSDRRTLAVFDDALNLNPVSRNPTRLSPETMTEVLATPLSDRLGRFLRARTGEPAVGRISVIVVTYNQLAFSRLCLESVLANSSMADLEVIVVDNGSHDGTPHYLAELAALTPSVRPLLNAENRGFAQANNQGLAESTGDVLILLNNDTIVPPDWDARLVRHLKHSDLGLVGPLTNRTCNEAQLATDYTTYGGLVELADRLSEIEAGTRFEIGMLAMFCVAMRRDVWNQLGPIDERFGLGLFEDDDYARRAKAAGYRVVCARDAFVHHFGQASFGALNDGEYGRLWHHNRAMFEAKWQESWSPHSQRTDAYRMLVDRLRTAVRLHLPEGATAAVVSKGDEDLLDLGTRRAWHFPCDEAGSPLGHHPADGAQAVGHLLEWHRRGVEYLVIPAPQFWYLDFYQDLRTWLEESCPPPVRIADTCLIFDLRRLSRNGLPPYSLNTSSIAAPSSEGF
>NC_019892.1|WP_015247719.1|5466879_5468661_-|ABC-transporter-ATP-binding-protein
MRLYWRVLHYLKPYRGLAVASVLIIAATAMASLLTPWPLKILVDNALGGAPPPRIVVMILGPLAGDRAAVLALAVAGGLFIAFFNNLMHVLENYVNTKLNLSMGLDFRSDLFRHSQRLSMAFHDRRRSGMLIYQISYQCDAASGLIMAVPPLATNALTLFGMFAVIYLIDPKLALLSVSIVPLLYYSTRYYVKHIQPQIVRVKGFEAETLSVIHEAISMIRVIAAFGREDHEYRRYRAQGTQAVDERVRLTVRQTLFSLAVNMTTACGTALVLGYGAYHALKGRLTVGELLVILSYVAAVYKPLEAISQTVGSLQDQIVSLRLTLELLDTIPEVSDPPGARVSGRALGQVAFEGVQFRYADRVDTLKEIDFEVVPGQRVALVGPTGAGKTTLISLILRFYDPTHGRILLDGEDIRSLTLESLRKQVSLVLQEPLLFSDTIANNIRYGRLDATMDEIIDAAKAANAHQFICKLPDGYDTVVGERGAKLSGGERQRISVARAFLKNAPILLLDEPTSSIDSRTEAVILDALDRLMEGRTTFLVAHRLSTIRSVDTILVMDQGRVVGQGSHESLLHTCPLYRQLYELQSAPQRQPA

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Crispr_ID: NC_019892_21

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_21

8473165-8473253

Orphan

Consensus_repeat	Method
GGTTACGGAGGCCTGGGCTACGGCGGATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_21

>merge|NC_019892|21|8473165-8473253|CRISPRCasFinder
GGTTACGGAGGCCTGGGTTACGGAGGCCTGGGCTACGGCGGATTCGGTTACGGAGGCCTGGGCTACGGCGGGTTCGGTTACGGAGGCCT

>NC_019892|21|21|8473165-8473253|CRISPRCasFinder
GGTTACGGAGGCCTGGGTTACGGAGGCCT	GGGCTACGGCGGATTCGGTTACGGAGGCCTG
GGCTACGGCGGGTTCGGTTACGGAGGCCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_020466455.1\|8480894_8481956_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015249879.1\|8486195_8487053_+\|shikimate-dehydrogenase	unknown	unknown	gnl\|CDD\|223247
NC_019892.1\|WP_015249875.1\|8482160_8482691_-\|ribosomal-protein-S18-alanine-N-acetyltransferase	unknown	unknown	gnl\|CDD\|273701
NC_019892.1\|WP_015249860.1\|8461923_8462295_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015249863.1\|8464006_8464996_-\|sulfonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270275
NC_019892.1\|WP_015249867.1\|8469120_8470494_+\|DUF1800-domain-containing-protein	unknown	unknown	gnl\|CDD\|378055
NC_019892.1\|WP_015249873.1\|8479341_8480715_-\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|379140
NC_019892.1\|WP_044147910.1\|8462335_8463109_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|183055
NC_019892.1\|WP_015249876.1\|8483173_8484385_-\|DUF1571-domain-containing-protein	unknown	unknown	gnl\|CDD\|377879
NC_019892.1\|WP_015249859.1\|8460941_8461211_+\|carbon-storage-regulator-CsrA	unknown	unknown	gnl\|CDD\|224468
NC_019892.1\|WP_026012038.1\|8463108_8463855_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|183100
NC_019892.1\|WP_015249868.1\|8470576_8471824_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|226587
NC_019892.1\|WP_015249877.1\|8484745_8485426_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293792
NC_019892.1\|WP_015249872.1\|8477600_8479199_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NC_019892.1\|WP_015249864.1\|8465322_8466291_+\|TauD/TfdA-family-dioxygenase	unknown	unknown	gnl\|CDD\|367137
NC_019892.1\|WP_015249870.1\|8474898_8475699_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|372616
NC_019892.1\|WP_015249871.1\|8476267_8476933_-\|isoprenylcysteine-carboxylmethyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224931
NC_019892.1\|WP_015249878.1\|8485422_8486127_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|224682
NC_019892.1\|WP_015249865.1\|8466355_8466895_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|366133
NC_019892.1\|WP_015249866.1\|8467157_8468930_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371750

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015249879.1\|8486195_8487053_+\|shikimate-dehydrogenase	gnl\|CDD\|223247	COG0169, AroE, Shikimate 5-dehydrogenase [Amino acid transport and metabolism].	3.4129e-97
NC_019892.1\|WP_015249875.1\|8482160_8482691_-\|ribosomal-protein-S18-alanine-N-acetyltransferase	gnl\|CDD\|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR\|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	3.842e-26
NC_019892.1\|WP_015249863.1\|8464006_8464996_-\|sulfonate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270275	cd13557, PBP2_SsuA, Substrate binding domain of sulfonate binding protein, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes the sulfonate binding domains SsuA found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBPII superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.30769e-132
NC_019892.1\|WP_015249867.1\|8469120_8470494_+\|DUF1800-domain-containing-protein	gnl\|CDD\|378055	pfam08811, DUF1800, Protein of unknown function (DUF1800). This is a family of large bacterial proteins of unknown function.	4.46041e-134
NC_019892.1\|WP_015249873.1\|8479341_8480715_-\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	8.03006e-18
NC_019892.1\|WP_044147910.1\|8462335_8463109_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|183055	PRK11247, ssuB, aliphatic sulfonates transport ATP-binding subunit; Provisional.	5.27821e-104
NC_019892.1\|WP_015249876.1\|8483173_8484385_-\|DUF1571-domain-containing-protein	gnl\|CDD\|377879	pfam07608, DUF1571, Protein of unknown function (DUF1571). A family of paralogous proteins in Rhodopirellula baltica.	1.42474e-106
NC_019892.1\|WP_015249859.1\|8460941_8461211_+\|carbon-storage-regulator-CsrA	gnl\|CDD\|224468	COG1551, CsrA, RNA-binding global regulator CsrA [Signal transduction mechanisms].	4.00333e-23
NC_019892.1\|WP_026012038.1\|8463108_8463855_-\|ABC-transporter-permease-subunit	gnl\|CDD\|183100	PRK11365, ssuC, aliphatic sulfonate ABC transporter permease SsuC.	3.13327e-100
NC_019892.1\|WP_015249868.1\|8470576_8471824_+\|DUF1501-domain-containing-protein	gnl\|CDD\|226587	COG4102, COG4102, Uncharacterized protein conserved in bacteria [Function unknown].	1.21242e-56
NC_019892.1\|WP_015249877.1\|8484745_8485426_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	4.79859e-66
NC_019892.1\|WP_015249872.1\|8477600_8479199_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NC_019892.1\|WP_015249864.1\|8465322_8466291_+\|TauD/TfdA-family-dioxygenase	gnl\|CDD\|367137	pfam02668, TauD, Taurine catabolism dioxygenase TauD, TfdA family. This family consists of taurine catabolism dioxygenases of the TauD, TfdA family. TauD from E. coli is a alpha-ketoglutarate-dependent taurine dioxygenase. This enzyme catalyzes the oxygenolytic release of sulfite from taurine. TfdA from Burkholderia sp. is a 2,4-dichlorophenoxyacetic acid/alpha-ketoglutarate dioxygenase. TfdA from Alcaligenes eutrophus JMP134 is a 2,4-dichlorophenoxyacetate monooxygenase. Also included are gamma-Butyrobetaine hydroxylase enzymes EC:1.14.11.1.	9.19455e-33
NC_019892.1\|WP_015249870.1\|8474898_8475699_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|372616	pfam13489, Methyltransf_23, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.69481e-13
NC_019892.1\|WP_015249871.1\|8476267_8476933_-\|isoprenylcysteine-carboxylmethyltransferase-family-protein	gnl\|CDD\|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	1.23176e-22
NC_019892.1\|WP_015249878.1\|8485422_8486127_+\|metallophosphoesterase	gnl\|CDD\|224682	COG1768, COG1768, Predicted phosphohydrolase [General function prediction only].	2.35971e-53
NC_019892.1\|WP_015249865.1\|8466355_8466895_-\|FHA-domain-containing-protein	gnl\|CDD\|366133	pfam00498, FHA, FHA domain. The FHA (Forkhead-associated) domain is a phosphopeptide binding motif.	9.48896e-16
NC_019892.1\|WP_015249866.1\|8467157_8468930_+\|hypothetical-protein	gnl\|CDD\|371750	pfam11832, DUF3352, Protein of unknown function (DUF3352). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 538 to 575 amino acids in length.	0.000639245

>NC_019892.1|WP_015249868.1|8470576_8471824_+|DUF1501-domain-containing-protein
MRSHRRDFLKSSLAASTLVSMGSTTVPAFLARSAQAANARANDRVLVVVQLIGGNDGLNTVVPHGLDGYAKSRRVLRLPAGQIQTINKEVGLHPAMGGMAKLLEAGRLAVVQGVGYPNPDRSHFRSMEIWESARREEGALETGWIGRAIDAMPHPGGRDTPALHVGSRVLPLALKAKHSEAPSLESLEQYRLQLAGNAGDQRTMREALDQVARLDRAVDDPLLGFMRRSTLTAYDSSKRLEQVIKPATDKSQYPNYGLARRLELIAQIVKAGLGTRIFYTALDGFDTHANQLGTHAALLTELSDSIAAFQKDLATSGQADRVALLTFSEFGRRVAENASGGTDHGAAAPLFVVGPVKSAGLIGAHPSLEDLEDGDLKHHTDFRRVYASLLDAWLECPSAQTVGPGFEPLPLFRSV
>NC_019892.1|WP_015249867.1|8469120_8470494_+|DUF1800-domain-containing-protein
MHSSPLLTDPAQAWAPWNPDANNRWDLARVAHLHRRAGFAPSWAVIQRDLAAGPDASVDRLIDGEPTAGDGQPALAFDAMLDAMTEQLAEGASLARLQGIWLYRMVFTPHPLRERMTLFWHNHFATSHGKVKNSLLMQRQNDLLRSHALGDFKTLLAAIGKDPAMLIWLDSTENRKAQPNENYAREVMELFTLGRGRYTEKDVQEAARAFTGWFVVRDRFREIPGQHDPGPKQVLGRAGTLRGDDIPPILLEQPACAEFLCEKLIRQFVTEVDPISTALSASLALPFRESGYDIRVPLRTILRSNLFQSEAVRRRRVKSPVEFTIGTIRALEILKPTVQADALAQACGQMGQHLYAPPSVAGWEGGAAWANSTTMLARANFALALLSDQDGALGKRLNAQELAAKHGANPPQEACSFLIDLLVQDAFDRKVRDRVSAKGDPKEIAVTILTSPEYQLA
>NC_019892.1|WP_015249866.1|8467157_8468930_+|hypothetical-protein
MPRLGHRMRLGISRGITGLLLTLGVSTSMGGEVVHASRWVAGDAAIYLELSHTSPLLDRLLTDQYQNALAALPGSEKLTQSETYKQAVAVLEQITEKLGTTWQQGLRDLTGGGVVLAVEGKPARPILIVTPTDPAFLTRLNQALLDLAREKAKSKDQPDPVKSADYREITVYELDRKGVYAIVEGKLVIVDNPKTLKQVIDRALDGEKAGTSLADDADWKARRAQVGDPQAWGTVRIDRLRELDPKRFTFKGDPKLPATFLFGSWLEVLRKADWASAAFSWTDAGLGAELALPTPSGGYPEALKGFVPPNGRGATKPVNPPGTIASLSLWRDLSSLWEARADLFPPEAVQGLAKLDGVAGQFFGARDFGTDVLGPLGDEWRLVVARQDHASLKPVPDMKLPAFALVVDLKPGDNDFAQRLKVAFQSIVGLVNLGGAQSKSPPLELGAETVEDVTISTARYMLPKAAPNAKEPVHMRHNFSPSLAQVGNQLILSSSVSLTRSLIQTFKTPAKPEDATLMVKADGRELADLVEINKTRLVMQNMLEKGHDKTQAEREISVLTQLLRYLGLAQLSVQDSAETVKFKLSFDLAK
>NC_019892.1|WP_015249865.1|8466355_8466895_-|FHA-domain-containing-protein
MKAELVPDNGDPPIVIDRDLTVVGRRGFCDVTIDHPSLSKRHCVLVKTDGLLVVRDLGSTNGTKVKGQKIRWAALLPDDRLTLGGYKMRVYLGPDSAPGPSEKAQRGPSSRASKPTGGSKGRDGGASGFAPPSPLGTPTIKPSASWPVDPDGEGGGTSGSWREQMGALVDRDDLIIELD
>NC_019892.1|WP_015249864.1|8465322_8466291_+|TauD/TfdA-family-dioxygenase
MSEPTFPEIATDPRAWRKADVGPETSWRLPFPPELAGALVALARGGTSVIETQLDEADRLAWAPAFAGVLDDLERGRGFAIVEGPVGVELSPEARCALYWVVGQLLGHPVIQNVEGVRLYDVRDTGRTIGEGARFSVTNAESTFHTDASFEDEVVDYVGLLCLSPAKSGGLGQLVSGYTVHDELATAASKSLQTLAGAFQVDRRGGLRPGESPTALRPVIAKDERGGLIYRYLRTWIEVGHDKAGEPLSPAQTEALDALDRVLNRPELRVEFRLQPGDMFFANNRWTLHNRTAFEDHPDPERRRHYVRLWLSAHTGHLTSVD
>NC_019892.1|WP_015249863.1|8464006_8464996_-|sulfonate-ABC-transporter-substrate-binding-protein
MIRRRNLSGGWLTFLYLAFAWVAPGCAGGEGAQAEVTIGYQKTGSLNLLRLRGGLEPALAKLGVQVKWVGFPAGPQLLEALNAGSIDFGHTGDAPPILAQAAGVPFVYVGYEPARPRAEAILVPAGSPLKSVAELKGKRIALNKGSNVHYLLVRALERAGVRYDEVRTVFLPPADARAAFEGGSIDAWAAWDPYYAEAEARANARVLSDGDGLVANREFQLATREFARDHPDLVAAILAGLREQADWTQSHPDEAARLFGNEIGLELATVRRVIDRKAFGISPMDNAVVIEQQHVADVFAELGLIPAKLRVSEAVLTPNTGHLTQGVGR
>NC_019892.1|WP_026012038.1|8463108_8463855_-|ABC-transporter-permease-subunit
MVPWLVPALVVACWQAVSSLGWLPPRLLPSPLSVARAAVRLTASGELPRHVAVSTQRAALGFAIGGGIGLALGFLNGLSRTADRLFDTTLQMVRAVPHLALIPLVILWLGIGETAKVALVALGVVFPLYLNTLHGLKGLDPRLTELGRVHGLSRWQMLRRVVLPGALPSILVGLRYGLGLMWLTLIVAETVSADSGIGYLAMNAREFLQADVVLLSIVLYALLGKLADSATRWLERRLLPWHLGLHSR
>NC_019892.1|WP_044147910.1|8462335_8463109_-|ATP-binding-cassette-domain-containing-protein
MFTTETKKREAGVVRGVRLEIRGLCHCYGGRDVLRDLDLEIVPGEFVAVVGRSGSGKTTLLRLLAGLESPTYGAILQDGSPLSGLNRRARLMFQDARLLPWDRVAGNVGLGLPADRAGRVSWALEQVGLEDRAEDWPRTLSGGQQQRVALARALAGSPGLLLLDEPLGALDALTRIEMQALVAQVWQASGFTVVLVTHDVEEAVTLADRVIIVDQGRIASETQIHLPRPRRRDSPHYAGLAEQILARILTKNSETFC
>NC_019892.1|WP_015249860.1|8461923_8462295_+|hypothetical-protein
MNDAKSEMEAAAGERSAIVELRRLSRAGMIAVIYRGGRRRKAIPLTDGIVVEVPEPDQRCEAPQHLEACIGITAGGLPATVHHLNLGLVVDYGTFGGVYVLPSGEVAAIYGAEAIPLGSHNLE
>NC_019892.1|WP_015249859.1|8460941_8461211_+|carbon-storage-regulator-CsrA
MLVLSRHRDESIIIGDDIVITVVDIRGDKVRLGIAAPIEISVHRQEVYEAIQRENRQASRLDPHDARQLEHLNNPPLRRDLRRPRTDDI
>NC_019892.1|WP_015249870.1|8474898_8475699_-|class-I-SAM-dependent-methyltransferase
MLHIVEEPVVSRSLLTRCRLFLKYFMWPGTNWVSREKSRLVKMLIPGTSESPVRTLDCGCGNAYFAHQAVLRGAVCTGITIHEWERDHCEEMRDYLGVPKDRMSFQVVSLDHFAADEACRGKFDQILLLDVIEHILDADATLRQIHELLDEDGFVYITTPNRDWQANADHLRVSRIENGWHVRNGYTMEQLEAILERNQFEPIDRLRFGTLGSSVVTRIQHSLFRSRIDLLTVLFFPFLKLLALALSPWRDPHTIFVLARKKSRPN
>NC_019892.1|WP_015249871.1|8476267_8476933_-|isoprenylcysteine-carboxylmethyltransferase-family-protein
MKPLPTWGMVLFIAVSLVLYIGLAVWGWGGWSAFMAHPARAGAVVAMVVISVAAAFTSGNLSSGRREDTTNRWVLLPFIILGFVLGWLPAYTDRRGIGTIDGDVVRYFGLALFVVGSVLRLGAVFVLGRRFSGLVAIQEGHELVTGGLYRVIRHPSYLGLLLGLFGWVLVFRSAVGVLVSLLLLPPLVARMNSEEALLESEFGERYADYRRRTWRLLPFLY
>NC_019892.1|WP_015249872.1|8477600_8479199_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MHEIVPVRRALLSVSDKTGLIELARVLAGQGVHLLASGGTRTALTEAGLEVTEVSAYTGQPEILGGRVKTLHPKLHGGILARRELAEDLAALEAQGIEPIDLVVVNLYPFEATVARAEVTFEEAVENIDIGGPSLIRGAAKNHAHVAVLTDAAQYERLAKSLQEQGGTTLDERKALALAAFAKCARYDQAIADYLGQVVGSGDGETEAFPPTLHPRFERRAVLRYGENPHQRAAFYVEPGTVGPNLATAQSIHGKELSYNNLLDLDSALRLIRHFAEPAATILKHNNPCGAAIADTLAEAFELAYEGDPVSAFGGIVGLNRRVDRATAERLCAPGRFIEAIVAPGYDPDALALLTTKPTWKNSVRLLDLGGPIGPDAPAPAGFDLRRVEGGMLVQDWDTMEADPASGTVATKRVPTAAERVSLGFAWRVCQSVRSNAIVLVRDRQLVGVGAGQMSRLDSVRIAVSKAGERAEGAVLASDAFFPFRDGPDTAASAGVTALIQPGGSKRDNETLAACDEHGMAMILTGRRHFRH
>NC_019892.1|WP_015249873.1|8479341_8480715_-|PQQ-binding-like-beta-propeller-repeat-protein
MSRRIVLSWVFLALMGTSVCAQIPISRDLLPTRTALGRVGLERHWMAAVPMEPTEKLLEISMADNLIFAQTSHAGFHTFDAETGRLLWSAHLGHQLQDAFPASANSRMVFVTNSNQLFALDRNTGRKVWVENLSVLPSSPTACDEEQVMVGLSTGVIRSFTLFVKDEKGVVVKDTKGQPLVSPRALFAWNWQTGGPLKSRPMPAGRMVVFGGHDGRAYVALADTPKMLYRIATGGAIEAPISAYGTRTFFVASADKNVYSVDLFTASVMWAFSAGAPVLQEPVVADRDVYVINTSGVMNAVEVGTGKARWSTPTHGGRLISISEKRLYLESYDEDLFIVDRESGQIVADPRSTYSRAGLNLRSYDLSLTNTLNDRLYLASSSGMIFSIREAGLTKPRLLRDPKAPKFGFIPPEGVPMEPPSGITAPSNLTAPEPGDEPKPADATPEDEPAPAPEEEK
>NC_019892.1|WP_020466455.1|8480894_8481956_-|hypothetical-protein
MTDIPDAAVGLIPGSTSPLARAQGESEPSRQAVPKVTPDLASIAPWLQAGFLIVGVFSALGSSSVLFAGPALPWSQKLPLILDALTRVFALALIGWLIARLVQALATALDVQAMRVATAESAERLLIAALGRVAEALERSATVAPSRSPVPADPAAEIGKAIQEAKWDHAGTLVREFIAAHPDEPDGSRLARELETSRAVEARSLRGKLDAAREANDPDRVLELRDAFRPLLDADALRTLDQELIRWLMALIQKRLRAGTIRVDVVELAAKVAERFDHTSEGASLRAALPTLRRSAGLCARCGKPYTGIDDACPDCLKAQSLPTFGTEFDPEVDPESTEGDDPDRALFSDDSV
>NC_019892.1|WP_015249875.1|8482160_8482691_-|ribosomal-protein-S18-alanine-N-acetyltransferase
MSTVPTTKAQVRVHIRWMIRRDMPEVLAIEHASFEYPWCEEEFLRVLRQRNCIGMVAEYGERVVGFMIYELHKNRLHVLDFATHPEFRRQGVGQQMVAKLVGKLSSHRRTRIALSVRETNLVGQLFFRIQGFRAMEVVREHYMDTAEDAYVMQYLLDESVLDEPMPTNRIAKQYEN
>NC_019892.1|WP_015249876.1|8483173_8484385_-|DUF1571-domain-containing-protein
MIPKPKQRFDIKDRGQAWKGRILTTLGTLGASATVWAGAGMGGETSRWELPDGTHLYSTAEAPFDYRGPVPTLLLAMLDPTAANNPRAEPRFDSSFLRAQNQAAEPNSVAAFSESEPAKSKASERETENAKEQERREVAPRVASAASRARTQSLEHPPGSTASLSTATAEASHDPIVMAKQAIADCEARYKKVQDYTCTFHKRERIDGRLTQPYIMAMKSRTHPHSIYFKFQRPKKGREAIYVAGRHGGKIVVHDVGLGKLIAGTMNLDPHGSMAMEENRHPVTEAGIGSLIASVARHWSIELTPGESRVTFHKDVRVGNRPCTMIESVHPEKHPSYLFHMVKLYIDHEHGLPIRFEAYDWPKRPGVSPELVEEYSYLNLQTNVGLRDQDFDAANPQYSYGRF
>NC_019892.1|WP_015249877.1|8484745_8485426_+|MBL-fold-metallo-hydrolase
MASTEYTIEAIQSAPFGEMSYVAWRRGQGEALVIDPGFDAEAILDLLSRQGLRLTAILNTHGHVDHIAGNAAMKQAYPDAPLIIGCNDAALLSDPQANLSAPFGFPLTSPPADQLVADGERLEAAGFSLEVREIPGHSPGSVVFVCDQFDTPFVFGGDVLFAGSVGRTDLGGNGPQLIAGIRAKLFNLPDATLVLPGHGPITTVANEKQSNPFVGERAGFHEIGPS
>NC_019892.1|WP_015249878.1|8485422_8486127_+|metallophosphoesterase
MTIWAIADLHLSFARPDRRERYAERWRDHVAKIEREWRSVIRPADLVLLPGDLSMARNHRDLQPDLNWLDRLPGTKVLAPGNHDTWWNDVEKIRPMLRKSLLAVDGDAVKTHGVVICGARGAPVPLEDDEDPKVIAASEEAMATLDRALEQAAPLRDQGEPLYVLWHYPPFDQHRRPGPCVARFEQAEVTTCLYGHLHIQGQWSLAVQGDVRGVRYQCVAADAIGFRPLQLTRP
>NC_019892.1|WP_015249879.1|8486195_8487053_+|shikimate-dehydrogenase
MSTIRSFKQELVGVFGFPVAENPTQAMIEPAFAAMGLDWRYLTVEVRPEDLGAAVRGARAMNWRGFNCTIPHKVAVIEHLDRLSPAAEKIGAVNCVINQGGEWVGDNTDGKGFLQSVHEVRPIPGLRAVVLGAGGAARAIGVELALAGAKHMTIVNRDRGRGQVLTKLISEKTGVPTDFSDWEERYQVPLGTDLVVNATSIGLYPDVEARVPIDLTTLRPGMIVSDVIPNPPRTWLIREAETRGCQVLDGLGMLVNQGVIGIRLWSGHEPDSNVMRKALESLFLP

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Crispr_ID: NC_019892_22

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_22

8473963-8474202

Orphan

Consensus_repeat	Method
CTCAACGGCCTCAATGCNAAC	CRT

5 spacers

The CRISPR arrays of NC_019892_22

>merge|NC_019892|22|8473963-8474202|CRT
CTCAACGGCCTCAATGCCAACGCAATCCACAACAGAGGTGCGAACCTCAACGGCCTCAACGCAATGCGAAACAACGGCGGAAACCTCAACGGACTGAATGCCAACGCATTGCGCCCCAACGGGGCCAACCTCAACGGCCTCAATGCCAACGCATTGCGCCCCAATGGGGCCAACCTCAACAGCCTCAATGCCAACGCATTGCGCCCCAACGGGGCCAACCTCAACGGCCTCAATGCTAAC

>NC_019892|22|6|8473963-8474202|CRT
CTCAACGGCCTCAATGCCAAC	GCAATCCACAACAGAGGTGCGAAC
CTCAACGGCCTCAACGCAATG	CGAAACAACGGCGGAAAC
CTCAACGGACTGAATGCCAAC	GCATTGCGCCCCAACGGGGCCAAC
CTCAACGGCCTCAATGCCAAC	GCATTGCGCCCCAATGGGGCCAAC
CTCAACAGCCTCAATGCCAAC	GCATTGCGCCCCAACGGGGCCAAC
CTCAACGGCCTCAATGCTAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_020466455.1\|8480894_8481956_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015249879.1\|8486195_8487053_+\|shikimate-dehydrogenase	unknown	unknown	gnl\|CDD\|223247
NC_019892.1\|WP_015249875.1\|8482160_8482691_-\|ribosomal-protein-S18-alanine-N-acetyltransferase	unknown	unknown	gnl\|CDD\|273701
NC_019892.1\|WP_015249860.1\|8461923_8462295_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015249863.1\|8464006_8464996_-\|sulfonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270275
NC_019892.1\|WP_015249867.1\|8469120_8470494_+\|DUF1800-domain-containing-protein	unknown	unknown	gnl\|CDD\|378055
NC_019892.1\|WP_015249873.1\|8479341_8480715_-\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|379140
NC_019892.1\|WP_044147910.1\|8462335_8463109_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|183055
NC_019892.1\|WP_015249876.1\|8483173_8484385_-\|DUF1571-domain-containing-protein	unknown	unknown	gnl\|CDD\|377879
NC_019892.1\|WP_015249859.1\|8460941_8461211_+\|carbon-storage-regulator-CsrA	unknown	unknown	gnl\|CDD\|224468
NC_019892.1\|WP_026012038.1\|8463108_8463855_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|183100
NC_019892.1\|WP_015249868.1\|8470576_8471824_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|226587
NC_019892.1\|WP_015249877.1\|8484745_8485426_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293792
NC_019892.1\|WP_015249872.1\|8477600_8479199_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NC_019892.1\|WP_015249864.1\|8465322_8466291_+\|TauD/TfdA-family-dioxygenase	unknown	unknown	gnl\|CDD\|367137
NC_019892.1\|WP_015249870.1\|8474898_8475699_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|372616
NC_019892.1\|WP_015249871.1\|8476267_8476933_-\|isoprenylcysteine-carboxylmethyltransferase-family-protein	unknown	unknown	gnl\|CDD\|224931
NC_019892.1\|WP_015249878.1\|8485422_8486127_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|224682
NC_019892.1\|WP_015249865.1\|8466355_8466895_-\|FHA-domain-containing-protein	unknown	unknown	gnl\|CDD\|366133
NC_019892.1\|WP_015249866.1\|8467157_8468930_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371750

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015249879.1\|8486195_8487053_+\|shikimate-dehydrogenase	gnl\|CDD\|223247	COG0169, AroE, Shikimate 5-dehydrogenase [Amino acid transport and metabolism].	3.4129e-97
NC_019892.1\|WP_015249875.1\|8482160_8482691_-\|ribosomal-protein-S18-alanine-N-acetyltransferase	gnl\|CDD\|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR\|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	3.842e-26
NC_019892.1\|WP_015249863.1\|8464006_8464996_-\|sulfonate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270275	cd13557, PBP2_SsuA, Substrate binding domain of sulfonate binding protein, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes the sulfonate binding domains SsuA found in eubacterial SsuA proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding the ligand, SsuA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The SsuA proteins belong to the PBPII superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.30769e-132
NC_019892.1\|WP_015249867.1\|8469120_8470494_+\|DUF1800-domain-containing-protein	gnl\|CDD\|378055	pfam08811, DUF1800, Protein of unknown function (DUF1800). This is a family of large bacterial proteins of unknown function.	4.46041e-134
NC_019892.1\|WP_015249873.1\|8479341_8480715_-\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|379140	pfam13360, PQQ_2, PQQ-like domain. This domain contains several repeats of the PQQ repeat.	8.03006e-18
NC_019892.1\|WP_044147910.1\|8462335_8463109_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|183055	PRK11247, ssuB, aliphatic sulfonates transport ATP-binding subunit; Provisional.	5.27821e-104
NC_019892.1\|WP_015249876.1\|8483173_8484385_-\|DUF1571-domain-containing-protein	gnl\|CDD\|377879	pfam07608, DUF1571, Protein of unknown function (DUF1571). A family of paralogous proteins in Rhodopirellula baltica.	1.42474e-106
NC_019892.1\|WP_015249859.1\|8460941_8461211_+\|carbon-storage-regulator-CsrA	gnl\|CDD\|224468	COG1551, CsrA, RNA-binding global regulator CsrA [Signal transduction mechanisms].	4.00333e-23
NC_019892.1\|WP_026012038.1\|8463108_8463855_-\|ABC-transporter-permease-subunit	gnl\|CDD\|183100	PRK11365, ssuC, aliphatic sulfonate ABC transporter permease SsuC.	3.13327e-100
NC_019892.1\|WP_015249868.1\|8470576_8471824_+\|DUF1501-domain-containing-protein	gnl\|CDD\|226587	COG4102, COG4102, Uncharacterized protein conserved in bacteria [Function unknown].	1.21242e-56
NC_019892.1\|WP_015249877.1\|8484745_8485426_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	4.79859e-66
NC_019892.1\|WP_015249872.1\|8477600_8479199_-\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NC_019892.1\|WP_015249864.1\|8465322_8466291_+\|TauD/TfdA-family-dioxygenase	gnl\|CDD\|367137	pfam02668, TauD, Taurine catabolism dioxygenase TauD, TfdA family. This family consists of taurine catabolism dioxygenases of the TauD, TfdA family. TauD from E. coli is a alpha-ketoglutarate-dependent taurine dioxygenase. This enzyme catalyzes the oxygenolytic release of sulfite from taurine. TfdA from Burkholderia sp. is a 2,4-dichlorophenoxyacetic acid/alpha-ketoglutarate dioxygenase. TfdA from Alcaligenes eutrophus JMP134 is a 2,4-dichlorophenoxyacetate monooxygenase. Also included are gamma-Butyrobetaine hydroxylase enzymes EC:1.14.11.1.	9.19455e-33
NC_019892.1\|WP_015249870.1\|8474898_8475699_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|372616	pfam13489, Methyltransf_23, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.69481e-13
NC_019892.1\|WP_015249871.1\|8476267_8476933_-\|isoprenylcysteine-carboxylmethyltransferase-family-protein	gnl\|CDD\|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	1.23176e-22
NC_019892.1\|WP_015249878.1\|8485422_8486127_+\|metallophosphoesterase	gnl\|CDD\|224682	COG1768, COG1768, Predicted phosphohydrolase [General function prediction only].	2.35971e-53
NC_019892.1\|WP_015249865.1\|8466355_8466895_-\|FHA-domain-containing-protein	gnl\|CDD\|366133	pfam00498, FHA, FHA domain. The FHA (Forkhead-associated) domain is a phosphopeptide binding motif.	9.48896e-16
NC_019892.1\|WP_015249866.1\|8467157_8468930_+\|hypothetical-protein	gnl\|CDD\|371750	pfam11832, DUF3352, Protein of unknown function (DUF3352). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 538 to 575 amino acids in length.	0.000639245

>NC_019892.1|WP_015249868.1|8470576_8471824_+|DUF1501-domain-containing-protein
MRSHRRDFLKSSLAASTLVSMGSTTVPAFLARSAQAANARANDRVLVVVQLIGGNDGLNTVVPHGLDGYAKSRRVLRLPAGQIQTINKEVGLHPAMGGMAKLLEAGRLAVVQGVGYPNPDRSHFRSMEIWESARREEGALETGWIGRAIDAMPHPGGRDTPALHVGSRVLPLALKAKHSEAPSLESLEQYRLQLAGNAGDQRTMREALDQVARLDRAVDDPLLGFMRRSTLTAYDSSKRLEQVIKPATDKSQYPNYGLARRLELIAQIVKAGLGTRIFYTALDGFDTHANQLGTHAALLTELSDSIAAFQKDLATSGQADRVALLTFSEFGRRVAENASGGTDHGAAAPLFVVGPVKSAGLIGAHPSLEDLEDGDLKHHTDFRRVYASLLDAWLECPSAQTVGPGFEPLPLFRSV
>NC_019892.1|WP_015249867.1|8469120_8470494_+|DUF1800-domain-containing-protein
MHSSPLLTDPAQAWAPWNPDANNRWDLARVAHLHRRAGFAPSWAVIQRDLAAGPDASVDRLIDGEPTAGDGQPALAFDAMLDAMTEQLAEGASLARLQGIWLYRMVFTPHPLRERMTLFWHNHFATSHGKVKNSLLMQRQNDLLRSHALGDFKTLLAAIGKDPAMLIWLDSTENRKAQPNENYAREVMELFTLGRGRYTEKDVQEAARAFTGWFVVRDRFREIPGQHDPGPKQVLGRAGTLRGDDIPPILLEQPACAEFLCEKLIRQFVTEVDPISTALSASLALPFRESGYDIRVPLRTILRSNLFQSEAVRRRRVKSPVEFTIGTIRALEILKPTVQADALAQACGQMGQHLYAPPSVAGWEGGAAWANSTTMLARANFALALLSDQDGALGKRLNAQELAAKHGANPPQEACSFLIDLLVQDAFDRKVRDRVSAKGDPKEIAVTILTSPEYQLA
>NC_019892.1|WP_015249866.1|8467157_8468930_+|hypothetical-protein
MPRLGHRMRLGISRGITGLLLTLGVSTSMGGEVVHASRWVAGDAAIYLELSHTSPLLDRLLTDQYQNALAALPGSEKLTQSETYKQAVAVLEQITEKLGTTWQQGLRDLTGGGVVLAVEGKPARPILIVTPTDPAFLTRLNQALLDLAREKAKSKDQPDPVKSADYREITVYELDRKGVYAIVEGKLVIVDNPKTLKQVIDRALDGEKAGTSLADDADWKARRAQVGDPQAWGTVRIDRLRELDPKRFTFKGDPKLPATFLFGSWLEVLRKADWASAAFSWTDAGLGAELALPTPSGGYPEALKGFVPPNGRGATKPVNPPGTIASLSLWRDLSSLWEARADLFPPEAVQGLAKLDGVAGQFFGARDFGTDVLGPLGDEWRLVVARQDHASLKPVPDMKLPAFALVVDLKPGDNDFAQRLKVAFQSIVGLVNLGGAQSKSPPLELGAETVEDVTISTARYMLPKAAPNAKEPVHMRHNFSPSLAQVGNQLILSSSVSLTRSLIQTFKTPAKPEDATLMVKADGRELADLVEINKTRLVMQNMLEKGHDKTQAEREISVLTQLLRYLGLAQLSVQDSAETVKFKLSFDLAK
>NC_019892.1|WP_015249865.1|8466355_8466895_-|FHA-domain-containing-protein
MKAELVPDNGDPPIVIDRDLTVVGRRGFCDVTIDHPSLSKRHCVLVKTDGLLVVRDLGSTNGTKVKGQKIRWAALLPDDRLTLGGYKMRVYLGPDSAPGPSEKAQRGPSSRASKPTGGSKGRDGGASGFAPPSPLGTPTIKPSASWPVDPDGEGGGTSGSWREQMGALVDRDDLIIELD
>NC_019892.1|WP_015249864.1|8465322_8466291_+|TauD/TfdA-family-dioxygenase
MSEPTFPEIATDPRAWRKADVGPETSWRLPFPPELAGALVALARGGTSVIETQLDEADRLAWAPAFAGVLDDLERGRGFAIVEGPVGVELSPEARCALYWVVGQLLGHPVIQNVEGVRLYDVRDTGRTIGEGARFSVTNAESTFHTDASFEDEVVDYVGLLCLSPAKSGGLGQLVSGYTVHDELATAASKSLQTLAGAFQVDRRGGLRPGESPTALRPVIAKDERGGLIYRYLRTWIEVGHDKAGEPLSPAQTEALDALDRVLNRPELRVEFRLQPGDMFFANNRWTLHNRTAFEDHPDPERRRHYVRLWLSAHTGHLTSVD
>NC_019892.1|WP_015249863.1|8464006_8464996_-|sulfonate-ABC-transporter-substrate-binding-protein
MIRRRNLSGGWLTFLYLAFAWVAPGCAGGEGAQAEVTIGYQKTGSLNLLRLRGGLEPALAKLGVQVKWVGFPAGPQLLEALNAGSIDFGHTGDAPPILAQAAGVPFVYVGYEPARPRAEAILVPAGSPLKSVAELKGKRIALNKGSNVHYLLVRALERAGVRYDEVRTVFLPPADARAAFEGGSIDAWAAWDPYYAEAEARANARVLSDGDGLVANREFQLATREFARDHPDLVAAILAGLREQADWTQSHPDEAARLFGNEIGLELATVRRVIDRKAFGISPMDNAVVIEQQHVADVFAELGLIPAKLRVSEAVLTPNTGHLTQGVGR
>NC_019892.1|WP_026012038.1|8463108_8463855_-|ABC-transporter-permease-subunit
MVPWLVPALVVACWQAVSSLGWLPPRLLPSPLSVARAAVRLTASGELPRHVAVSTQRAALGFAIGGGIGLALGFLNGLSRTADRLFDTTLQMVRAVPHLALIPLVILWLGIGETAKVALVALGVVFPLYLNTLHGLKGLDPRLTELGRVHGLSRWQMLRRVVLPGALPSILVGLRYGLGLMWLTLIVAETVSADSGIGYLAMNAREFLQADVVLLSIVLYALLGKLADSATRWLERRLLPWHLGLHSR
>NC_019892.1|WP_044147910.1|8462335_8463109_-|ATP-binding-cassette-domain-containing-protein
MFTTETKKREAGVVRGVRLEIRGLCHCYGGRDVLRDLDLEIVPGEFVAVVGRSGSGKTTLLRLLAGLESPTYGAILQDGSPLSGLNRRARLMFQDARLLPWDRVAGNVGLGLPADRAGRVSWALEQVGLEDRAEDWPRTLSGGQQQRVALARALAGSPGLLLLDEPLGALDALTRIEMQALVAQVWQASGFTVVLVTHDVEEAVTLADRVIIVDQGRIASETQIHLPRPRRRDSPHYAGLAEQILARILTKNSETFC
>NC_019892.1|WP_015249860.1|8461923_8462295_+|hypothetical-protein
MNDAKSEMEAAAGERSAIVELRRLSRAGMIAVIYRGGRRRKAIPLTDGIVVEVPEPDQRCEAPQHLEACIGITAGGLPATVHHLNLGLVVDYGTFGGVYVLPSGEVAAIYGAEAIPLGSHNLE
>NC_019892.1|WP_015249859.1|8460941_8461211_+|carbon-storage-regulator-CsrA
MLVLSRHRDESIIIGDDIVITVVDIRGDKVRLGIAAPIEISVHRQEVYEAIQRENRQASRLDPHDARQLEHLNNPPLRRDLRRPRTDDI
>NC_019892.1|WP_015249870.1|8474898_8475699_-|class-I-SAM-dependent-methyltransferase
MLHIVEEPVVSRSLLTRCRLFLKYFMWPGTNWVSREKSRLVKMLIPGTSESPVRTLDCGCGNAYFAHQAVLRGAVCTGITIHEWERDHCEEMRDYLGVPKDRMSFQVVSLDHFAADEACRGKFDQILLLDVIEHILDADATLRQIHELLDEDGFVYITTPNRDWQANADHLRVSRIENGWHVRNGYTMEQLEAILERNQFEPIDRLRFGTLGSSVVTRIQHSLFRSRIDLLTVLFFPFLKLLALALSPWRDPHTIFVLARKKSRPN
>NC_019892.1|WP_015249871.1|8476267_8476933_-|isoprenylcysteine-carboxylmethyltransferase-family-protein
MKPLPTWGMVLFIAVSLVLYIGLAVWGWGGWSAFMAHPARAGAVVAMVVISVAAAFTSGNLSSGRREDTTNRWVLLPFIILGFVLGWLPAYTDRRGIGTIDGDVVRYFGLALFVVGSVLRLGAVFVLGRRFSGLVAIQEGHELVTGGLYRVIRHPSYLGLLLGLFGWVLVFRSAVGVLVSLLLLPPLVARMNSEEALLESEFGERYADYRRRTWRLLPFLY
>NC_019892.1|WP_015249872.1|8477600_8479199_-|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MHEIVPVRRALLSVSDKTGLIELARVLAGQGVHLLASGGTRTALTEAGLEVTEVSAYTGQPEILGGRVKTLHPKLHGGILARRELAEDLAALEAQGIEPIDLVVVNLYPFEATVARAEVTFEEAVENIDIGGPSLIRGAAKNHAHVAVLTDAAQYERLAKSLQEQGGTTLDERKALALAAFAKCARYDQAIADYLGQVVGSGDGETEAFPPTLHPRFERRAVLRYGENPHQRAAFYVEPGTVGPNLATAQSIHGKELSYNNLLDLDSALRLIRHFAEPAATILKHNNPCGAAIADTLAEAFELAYEGDPVSAFGGIVGLNRRVDRATAERLCAPGRFIEAIVAPGYDPDALALLTTKPTWKNSVRLLDLGGPIGPDAPAPAGFDLRRVEGGMLVQDWDTMEADPASGTVATKRVPTAAERVSLGFAWRVCQSVRSNAIVLVRDRQLVGVGAGQMSRLDSVRIAVSKAGERAEGAVLASDAFFPFRDGPDTAASAGVTALIQPGGSKRDNETLAACDEHGMAMILTGRRHFRH
>NC_019892.1|WP_015249873.1|8479341_8480715_-|PQQ-binding-like-beta-propeller-repeat-protein
MSRRIVLSWVFLALMGTSVCAQIPISRDLLPTRTALGRVGLERHWMAAVPMEPTEKLLEISMADNLIFAQTSHAGFHTFDAETGRLLWSAHLGHQLQDAFPASANSRMVFVTNSNQLFALDRNTGRKVWVENLSVLPSSPTACDEEQVMVGLSTGVIRSFTLFVKDEKGVVVKDTKGQPLVSPRALFAWNWQTGGPLKSRPMPAGRMVVFGGHDGRAYVALADTPKMLYRIATGGAIEAPISAYGTRTFFVASADKNVYSVDLFTASVMWAFSAGAPVLQEPVVADRDVYVINTSGVMNAVEVGTGKARWSTPTHGGRLISISEKRLYLESYDEDLFIVDRESGQIVADPRSTYSRAGLNLRSYDLSLTNTLNDRLYLASSSGMIFSIREAGLTKPRLLRDPKAPKFGFIPPEGVPMEPPSGITAPSNLTAPEPGDEPKPADATPEDEPAPAPEEEK
>NC_019892.1|WP_020466455.1|8480894_8481956_-|hypothetical-protein
MTDIPDAAVGLIPGSTSPLARAQGESEPSRQAVPKVTPDLASIAPWLQAGFLIVGVFSALGSSSVLFAGPALPWSQKLPLILDALTRVFALALIGWLIARLVQALATALDVQAMRVATAESAERLLIAALGRVAEALERSATVAPSRSPVPADPAAEIGKAIQEAKWDHAGTLVREFIAAHPDEPDGSRLARELETSRAVEARSLRGKLDAAREANDPDRVLELRDAFRPLLDADALRTLDQELIRWLMALIQKRLRAGTIRVDVVELAAKVAERFDHTSEGASLRAALPTLRRSAGLCARCGKPYTGIDDACPDCLKAQSLPTFGTEFDPEVDPESTEGDDPDRALFSDDSV
>NC_019892.1|WP_015249875.1|8482160_8482691_-|ribosomal-protein-S18-alanine-N-acetyltransferase
MSTVPTTKAQVRVHIRWMIRRDMPEVLAIEHASFEYPWCEEEFLRVLRQRNCIGMVAEYGERVVGFMIYELHKNRLHVLDFATHPEFRRQGVGQQMVAKLVGKLSSHRRTRIALSVRETNLVGQLFFRIQGFRAMEVVREHYMDTAEDAYVMQYLLDESVLDEPMPTNRIAKQYEN
>NC_019892.1|WP_015249876.1|8483173_8484385_-|DUF1571-domain-containing-protein
MIPKPKQRFDIKDRGQAWKGRILTTLGTLGASATVWAGAGMGGETSRWELPDGTHLYSTAEAPFDYRGPVPTLLLAMLDPTAANNPRAEPRFDSSFLRAQNQAAEPNSVAAFSESEPAKSKASERETENAKEQERREVAPRVASAASRARTQSLEHPPGSTASLSTATAEASHDPIVMAKQAIADCEARYKKVQDYTCTFHKRERIDGRLTQPYIMAMKSRTHPHSIYFKFQRPKKGREAIYVAGRHGGKIVVHDVGLGKLIAGTMNLDPHGSMAMEENRHPVTEAGIGSLIASVARHWSIELTPGESRVTFHKDVRVGNRPCTMIESVHPEKHPSYLFHMVKLYIDHEHGLPIRFEAYDWPKRPGVSPELVEEYSYLNLQTNVGLRDQDFDAANPQYSYGRF
>NC_019892.1|WP_015249877.1|8484745_8485426_+|MBL-fold-metallo-hydrolase
MASTEYTIEAIQSAPFGEMSYVAWRRGQGEALVIDPGFDAEAILDLLSRQGLRLTAILNTHGHVDHIAGNAAMKQAYPDAPLIIGCNDAALLSDPQANLSAPFGFPLTSPPADQLVADGERLEAAGFSLEVREIPGHSPGSVVFVCDQFDTPFVFGGDVLFAGSVGRTDLGGNGPQLIAGIRAKLFNLPDATLVLPGHGPITTVANEKQSNPFVGERAGFHEIGPS
>NC_019892.1|WP_015249878.1|8485422_8486127_+|metallophosphoesterase
MTIWAIADLHLSFARPDRRERYAERWRDHVAKIEREWRSVIRPADLVLLPGDLSMARNHRDLQPDLNWLDRLPGTKVLAPGNHDTWWNDVEKIRPMLRKSLLAVDGDAVKTHGVVICGARGAPVPLEDDEDPKVIAASEEAMATLDRALEQAAPLRDQGEPLYVLWHYPPFDQHRRPGPCVARFEQAEVTTCLYGHLHIQGQWSLAVQGDVRGVRYQCVAADAIGFRPLQLTRP
>NC_019892.1|WP_015249879.1|8486195_8487053_+|shikimate-dehydrogenase
MSTIRSFKQELVGVFGFPVAENPTQAMIEPAFAAMGLDWRYLTVEVRPEDLGAAVRGARAMNWRGFNCTIPHKVAVIEHLDRLSPAAEKIGAVNCVINQGGEWVGDNTDGKGFLQSVHEVRPIPGLRAVVLGAGGAARAIGVELALAGAKHMTIVNRDRGRGQVLTKLISEKTGVPTDFSDWEERYQVPLGTDLVVNATSIGLYPDVEARVPIDLTTLRPGMIVSDVIPNPPRTWLIREAETRGCQVLDGLGMLVNQGVIGIRLWSGHEPDSNVMRKALESLFLP

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Crispr_ID: NC_019892_23

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_23

8496299-8496382

Orphan

Consensus_repeat	Method
CGGAACCACCGAGCCAGCCCGCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_23

>merge|NC_019892|23|8496299-8496382|CRISPRCasFinder
CGGAACCACCGAGCCAGCCCGCAACACTCGCTGAGTTGCCGGCCGAGTCTCCTGCTCTGACGGAACCGCCGAGCCAGCCCGCAA

>NC_019892|23|22|8496299-8496382|CRISPRCasFinder
CGGAACCACCGAGCCAGCCCGCAA	CACTCGCTGAGTTGCCGGCCGAGTCTCCTGCTCTGA
CGGAACCGCCGAGCCAGCCCGCAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015249894.1\|8510816_8512040_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015249884.1\|8494633_8494915_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015249892.1\|8507191_8508712_-\|neutral/alkaline-non-lysosomal-ceramidase-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|368090
NC_019892.1\|WP_015249875.1\|8482160_8482691_-\|ribosomal-protein-S18-alanine-N-acetyltransferase	unknown	unknown	gnl\|CDD\|273701
NC_019892.1\|WP_015249882.1\|8488702_8491456_+\|glycosyl-hydrolase	unknown	unknown	gnl\|CDD\|273702
NC_019892.1\|WP_015249890.1\|8502607_8504065_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NC_019892.1\|WP_015249883.1\|8491781_8494580_-\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_157579477.1\|8504320_8505271_+\|ROK-family-protein	unknown	unknown	gnl\|CDD\|224851
NC_019892.1\|WP_015249876.1\|8483173_8484385_-\|DUF1571-domain-containing-protein	unknown	unknown	gnl\|CDD\|377879
NC_019892.1\|WP_015249886.1\|8497269_8497515_+\|DUF3006-domain-containing-protein	unknown	unknown	gnl\|CDD\|378598
NC_019892.1\|WP_015249878.1\|8485422_8486127_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|224682
NC_019892.1\|WP_015249893.1\|8509081_8510677_-\|DUF1549-domain-containing-protein	unknown	unknown	gnl\|CDD\|377872
NC_019892.1\|WP_015249877.1\|8484745_8485426_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293792
NC_019892.1\|WP_015249881.1\|8487579_8488473_-\|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl\|CDD\|366542
NC_019892.1\|WP_015249879.1\|8486195_8487053_+\|shikimate-dehydrogenase	unknown	unknown	gnl\|CDD\|223247
NC_019892.1\|WP_015249888.1\|8498683_8499994_-\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NC_019892.1\|WP_015249887.1\|8497511_8498630_+\|helix-hairpin-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225212
NC_019892.1\|WP_015249880.1\|8487350_8487551_+\|carbon-storage-regulator-CsrA	unknown	unknown	gnl\|CDD\|376847
NC_019892.1\|WP_015249889.1\|8500322_8502581_+\|DUF1549-domain-containing-protein	unknown	unknown	gnl\|CDD\|377872
NC_019892.1\|WP_015244773.1\|8505554_8506979_-\|IS1380-family-transposase	unknown	unknown	gnl\|CDD\|379340

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015249892.1\|8507191_8508712_-\|neutral/alkaline-non-lysosomal-ceramidase-N-terminal-domain-containing-protein	gnl\|CDD\|368090	pfam04734, Ceramidase_alk, Neutral/alkaline non-lysosomal ceramidase, N-terminal. This family represents N-terminal domain of a group of neutral/alkaline ceramidases found in both bacteria and eukaryotes. The EC classification is EC:3.5.1.23. The enzyme hydrolyzes ceramide to generate sphingosine and fatty acid. The enzyme plays a regulatory role in a variety of physiological events in eukaryotes and also functions as an exotoxin in particular bacteria. This N-terminal domain carries two metal-binding sites, the first for Zn2+ residing within the domain, and the second, for Mg2+/Ca2+ lying at the interface between the two domains.	1.42477e-06
NC_019892.1\|WP_015249875.1\|8482160_8482691_-\|ribosomal-protein-S18-alanine-N-acetyltransferase	gnl\|CDD\|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR\|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	3.842e-26
NC_019892.1\|WP_015249882.1\|8488702_8491456_+\|glycosyl-hydrolase	gnl\|CDD\|273702	TIGR01577, Uncharacterized_glycosyl_hydrolase_MJ1610, oligosaccharide amylase. The name of this type of amylase is based on the characterization of an glucoamylase family enzyme from Thermoactinomyces vulgaris. The T. vulgaris enzyme was expressed in E. coli and, like other glucoamylases, it releases beta-D-glucose from starch. However, unlike previously characterized glucoamylases, this T. vulgaris amylase hydrolyzes maltooligosaccharides (maltotetraose, maltose) more efficiently than starch (1), indicating this enzyme belongs to a class of glucoamylase-type enzymes with oligosaccharide-metabolizing activity.	1.33213e-35
NC_019892.1\|WP_015249890.1\|8502607_8504065_+\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	2.19205e-173
NC_019892.1\|WP_157579477.1\|8504320_8505271_+\|ROK-family-protein	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	3.32533e-45
NC_019892.1\|WP_015249876.1\|8483173_8484385_-\|DUF1571-domain-containing-protein	gnl\|CDD\|377879	pfam07608, DUF1571, Protein of unknown function (DUF1571). A family of paralogous proteins in Rhodopirellula baltica.	1.42474e-106
NC_019892.1\|WP_015249886.1\|8497269_8497515_+\|DUF3006-domain-containing-protein	gnl\|CDD\|378598	pfam11213, DUF3006, Protein of unknown function (DUF3006). This family of proteins has no known function.	1.53284e-09
NC_019892.1\|WP_015249878.1\|8485422_8486127_+\|metallophosphoesterase	gnl\|CDD\|224682	COG1768, COG1768, Predicted phosphohydrolase [General function prediction only].	2.35971e-53
NC_019892.1\|WP_015249893.1\|8509081_8510677_-\|DUF1549-domain-containing-protein	gnl\|CDD\|377872	pfam07583, PSCyt2, Protein of unknown function (DUF1549). A family of paralogues in the planctomyces.	1.14316e-44
NC_019892.1\|WP_015249877.1\|8484745_8485426_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	4.79859e-66
NC_019892.1\|WP_015249881.1\|8487579_8488473_-\|sugar-phosphate-isomerase/epimerase	gnl\|CDD\|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	8.60647e-18
NC_019892.1\|WP_015249879.1\|8486195_8487053_+\|shikimate-dehydrogenase	gnl\|CDD\|223247	COG0169, AroE, Shikimate 5-dehydrogenase [Amino acid transport and metabolism].	3.4129e-97
NC_019892.1\|WP_015249888.1\|8498683_8499994_-\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	5.19647e-104
NC_019892.1\|WP_015249887.1\|8497511_8498630_+\|helix-hairpin-helix-domain-containing-protein	gnl\|CDD\|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	1.94068e-67
NC_019892.1\|WP_015249880.1\|8487350_8487551_+\|carbon-storage-regulator-CsrA	gnl\|CDD\|376847	pfam02599, CsrA, Global regulator protein family. This is a family of global regulator proteins. This protein is a RNA-binding protein and a global regulator of carbohydrate metabolism genes facilitating mRNA decay. In E. coli CsrA binds the CsrB RNA molecule to form the Csr regulatory system which has a strong negative regulatory effect on glycogen biosynthesis, glyconeogenesis and glycogen catabolism and a positive regulatory effect on glycolysis. In other bacteria such as Erwinia caratovara RmsA has been shown to regulate the production of virulence determinants, such extracellular enzymes. RmsA binds to RmsB regulatory RNA.	5.20442e-22
NC_019892.1\|WP_015249889.1\|8500322_8502581_+\|DUF1549-domain-containing-protein	gnl\|CDD\|377872	pfam07583, PSCyt2, Protein of unknown function (DUF1549). A family of paralogues in the planctomyces.	4.28247e-115
NC_019892.1\|WP_015244773.1\|8505554_8506979_-\|IS1380-family-transposase	gnl\|CDD\|379340	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	0

>NC_019892.1|WP_015249884.1|8494633_8494915_-|hypothetical-protein
MEKTTFHYQPMCSAPHCDAAAVYKVAAPWSNGKSRELKNYGLACEAHRDSQLALAQLHRQGLKLAEGETIGPVGLYELAAGKRDAELARLPDH
>NC_019892.1|WP_015249883.1|8491781_8494580_-|hypothetical-protein
MPSRLRIAAQWACRAGTAMVALVISADAIAGEIPGATRIHNLFAQFELPDNWETRFWADPNVKLLLTLDTKALAELVPVQAGVRHCRCPACDATEASNSLTWSVTNPKVLTCRNCQATVPNETYPAKDEKEKKVPEDVVQVLHGVTHQYPYHAVEPGKQRFPDEKLYLAAKRDYEAREFLAKAALYAAVRHHEQPAGSKDPALARLASVLILRFAQVYPAYATHFDQPHSPKVFQQANLPPPYRRGYQTGKWDWTASLDVPLNLLIAYALIRDQPALLEAGRSLNDDHPARTIERDLFRASAEFVRLQREEYSEVSLHAYRGLLAAGRLLDDPQLVGEAIRRLDGFSERGFYYDGFWRQGDAAAHRRILSVFDGWIDRLLAGYPEAPRPLELTSELKSAPARDLGALPMLALARRAGSAALSDSRVPEIQQVSWPAAVVAPGTRRPSLLGGVGLARLAIGEKGGSLDLEVRGQDNIGAPHFQRQALRLAVGGQLILGDLDEQPPTVTGWDRATVSHNTVVVDGLNQRESLGKASEPALGGDFLFFAADPDFQVLSLDDPRAYPQSTTRYRQTLVAASGAQSSYALSVFEVHGGLQHDQLYHAASGSRARWQLSVAMGPGPATLLPESIPYVPTARAEDGRWFVQAYGEFAPLAQVRLIRPAMAWLGSPGSPGVRLHLLGPTPIELITANSPDPATGSARTDAEDSGRAGLLLRHRSPDGSTLKTTFVTVFEPTGSSVVPLTRVGRVASSPETVVVYIESPGGGEHVVVNLAPGTTQSVNLADGRALRTDGLVVRVSSRGLVLAGGTFAESAGLRVEQQPSTGSITGVVRQASAAGRGWFESDQTLRDDGNMAGRTVLIRHGNDVTRAWTLQRVENMNRGSRLYVLEEPGFTLDKKSSAEASYYQFPRISAPGPHQFRVSKITRIQPPKTSPD
>NC_019892.1|WP_015249882.1|8488702_8491456_+|glycosyl-hydrolase
MVATWIEAAAKGRHGGPVRAGMWSAVVIGTHPIEANQVVWLEISADDTPLGPLPAYWIENKGVNSLWHVPVPPQAVGVRLHYRSAARQEGSETVYSPPQDTVVRPNMPDRTEAAEIVAMGPEGLVGNRMMTVRVDSRGSTYDVYFPTVGLHSDVRPAEGDMPQSRSHFRAIVGGLAVGRRLDWFTERLSWESFQHYLGATNLLMTELNSRTGPIRVLVTDFVAMAKSLPKTAGGTESPGQYLKRFRIKNDGPESLRALFGVYIQAEVNGGIGEPGLSWHDGDRTLLATNRGHGHANRKFARDATVEFAVALDDRGDVHCEPTGANEAILLRRIDLPAGETVTVDLLVSGAFTGWRGDPGTFEHWLRPALAWFRSADLDQVEQTTCQEWDAFTEVLPSLKYPKPAYAVSLRRSALASALHADAFWGAIASGFDRGLSAYCWPRDAMWAADTMERLGHPSIGRGLFEWLSHVRGQNRPYSYWFQKYTIDGGPEWETPAVDQTAMIPWGLERYYLRTADRDFLASMWPMIEQAATVCSGTSGHPGLSWIDDLSLISSAGLWDHRFGAFLYSNGCVVAGLRAAARLADVLDHPEHATRWRTLAERIWEIGILGQGTSDPDRADAPGLIDTETGRFLEARRLSTLRGLWTNRPEMQIERSKALDVSVLGLVVPFGLFPASDPRVVRTAEAILRLNAVGVDSNTLARWSLDATAPTASVPPSESHSHDLSSLATLWAARYLIQLGRETGQVRHWNRALAMTDGTLSRMLPLGLMLRPVIRANDSPRYIPGVASGVWGLHAMLVETMLEFARLDYNHVERRLDLDPALPSSWPHLGLTQTFPCGEVSFRLERPIGGTVHHLSLTVNLKHPIAFHAALTCPGLTELGPWQSAPESPPPTYDPRISRLSWSVTLPEGQSTWSWRWG
>NC_019892.1|WP_015249881.1|8487579_8488473_-|sugar-phosphate-isomerase/epimerase
MFSSFNARALGLTLSTLETIELASAAGFGGVDFLMRELRAEQVDPRAVRTRLEDLGLKAGAWSLPVDWRGDAARFAEDLEQLSRYAEAASVLGASRTGTWVMPETLANAGLDGDRASILASTAELHIERLGAIARVLANHGVRLGLEVIGVESFRSGRGIPFVTRLAELDLELGAIWQESTNLGILVDGFHLYAANEEIEAGFRWGVDRIVWVHVADLPASSPSDRSAIQDHDRGLPGENGAIDTAQLLKKLAEAGYSGPVTAEPGAKCRSIAGRSAKEIARLVASAMNSVWPQPTP
>NC_019892.1|WP_015249880.1|8487350_8487551_+|carbon-storage-regulator-CsrA
MLVLSRKLGEKIVIGDNIVVTVVKIDRNQIRIGIEAPHEVPVYREEIAPARSMKTVADEPAPVLNR
>NC_019892.1|WP_015249879.1|8486195_8487053_+|shikimate-dehydrogenase
MSTIRSFKQELVGVFGFPVAENPTQAMIEPAFAAMGLDWRYLTVEVRPEDLGAAVRGARAMNWRGFNCTIPHKVAVIEHLDRLSPAAEKIGAVNCVINQGGEWVGDNTDGKGFLQSVHEVRPIPGLRAVVLGAGGAARAIGVELALAGAKHMTIVNRDRGRGQVLTKLISEKTGVPTDFSDWEERYQVPLGTDLVVNATSIGLYPDVEARVPIDLTTLRPGMIVSDVIPNPPRTWLIREAETRGCQVLDGLGMLVNQGVIGIRLWSGHEPDSNVMRKALESLFLP
>NC_019892.1|WP_015249878.1|8485422_8486127_+|metallophosphoesterase
MTIWAIADLHLSFARPDRRERYAERWRDHVAKIEREWRSVIRPADLVLLPGDLSMARNHRDLQPDLNWLDRLPGTKVLAPGNHDTWWNDVEKIRPMLRKSLLAVDGDAVKTHGVVICGARGAPVPLEDDEDPKVIAASEEAMATLDRALEQAAPLRDQGEPLYVLWHYPPFDQHRRPGPCVARFEQAEVTTCLYGHLHIQGQWSLAVQGDVRGVRYQCVAADAIGFRPLQLTRP
>NC_019892.1|WP_015249877.1|8484745_8485426_+|MBL-fold-metallo-hydrolase
MASTEYTIEAIQSAPFGEMSYVAWRRGQGEALVIDPGFDAEAILDLLSRQGLRLTAILNTHGHVDHIAGNAAMKQAYPDAPLIIGCNDAALLSDPQANLSAPFGFPLTSPPADQLVADGERLEAAGFSLEVREIPGHSPGSVVFVCDQFDTPFVFGGDVLFAGSVGRTDLGGNGPQLIAGIRAKLFNLPDATLVLPGHGPITTVANEKQSNPFVGERAGFHEIGPS
>NC_019892.1|WP_015249876.1|8483173_8484385_-|DUF1571-domain-containing-protein
MIPKPKQRFDIKDRGQAWKGRILTTLGTLGASATVWAGAGMGGETSRWELPDGTHLYSTAEAPFDYRGPVPTLLLAMLDPTAANNPRAEPRFDSSFLRAQNQAAEPNSVAAFSESEPAKSKASERETENAKEQERREVAPRVASAASRARTQSLEHPPGSTASLSTATAEASHDPIVMAKQAIADCEARYKKVQDYTCTFHKRERIDGRLTQPYIMAMKSRTHPHSIYFKFQRPKKGREAIYVAGRHGGKIVVHDVGLGKLIAGTMNLDPHGSMAMEENRHPVTEAGIGSLIASVARHWSIELTPGESRVTFHKDVRVGNRPCTMIESVHPEKHPSYLFHMVKLYIDHEHGLPIRFEAYDWPKRPGVSPELVEEYSYLNLQTNVGLRDQDFDAANPQYSYGRF
>NC_019892.1|WP_015249875.1|8482160_8482691_-|ribosomal-protein-S18-alanine-N-acetyltransferase
MSTVPTTKAQVRVHIRWMIRRDMPEVLAIEHASFEYPWCEEEFLRVLRQRNCIGMVAEYGERVVGFMIYELHKNRLHVLDFATHPEFRRQGVGQQMVAKLVGKLSSHRRTRIALSVRETNLVGQLFFRIQGFRAMEVVREHYMDTAEDAYVMQYLLDESVLDEPMPTNRIAKQYEN
>NC_019892.1|WP_015249886.1|8497269_8497515_+|DUF3006-domain-containing-protein
MKTRLSFDRLEGERKEIAVLLADDGTSINLPKRFLPKAARPGDVLSLSLTRDIQATRRLADETRAIQAELKATDPGGDIKL
>NC_019892.1|WP_015249887.1|8497511_8498630_+|helix-hairpin-helix-domain-containing-protein
MRGLSSFIVSLCLCIPLASCAPPAPPHAMPGAVTVSILDVGQGDAILVRSPEGKTALIDAGQSSSNIVSTLEQQGISTLDLVVVSHHHADHYGGMEKVIRAYHPRVFLASSSSHTSEPYLRLLRLVRDRGIQAIGPLQAPRKIELGTVVLTIFPQAPNDPKEENNNSIGIRVEYGSFSVLLPGDAQTRERRWWERMAPNLCADATVLKLAHHGSRNGTDARWLDLVRPQVAVASMGKDNEYRHPHPEIVELLARSQIPLLRTDRDGTVTIRSDGLHWQVFTHPEVSTGWPIFDQRKSDRSRGDRRSPPKPSSGLININKASKTQLRKIPGVGQVIADRIIKGRPYRTVDDLVRVEGIGEKRLTEIRPYIRAR
>NC_019892.1|WP_015249888.1|8498683_8499994_-|DUF1501-domain-containing-protein
MGHRNGSVPGHAHRSRLDESLVFPGRRDLLKFAGLAGLSWLTPVGHLLASQAETRREPAQSVILIWLAGGPSQLETFDPHPGKPIAAGTRAIATAVKGVQLAQGYERLAEVMTSVSLVRSLVSQEGDHERGTYFMKNGYRPDPTVEHPSIGAICCHELPMGGTGIPRHISILPGQWPARGGFLGGEFDAFKTGDPLRPLPDVTSHVAPSRDAQRVIDLEVVERAFRRGRRSPVAATLHRETIERARVMMTSAQLKAFDVKQEPAAIRESYGDTPFGRACLAARRLTEVGVRCIEVTLDGWDTHVNNHATHRKLAGTLDPALSALIRDLKQRGTLDKTVVLCTGEFGRSPKVNLAGGRDHWPNGFSLAIAGGGIRGGLVIGETDPEGVKNPTKPTAVADIHATILKAVGLEPHKENVSPVGRPISLSQGTSIGALLS
>NC_019892.1|WP_015249889.1|8500322_8502581_+|DUF1549-domain-containing-protein
MRHTAGRMGQVLDRLQAVGIAAVGLVALGGTSVAGEAPDFDRQVAPILIMRCLECHNEAGAVGGLVLTGIDALKRGGESGEAIVAGKPEESLLLERVVDGEMPPKRQGHSQKLSEPEIETLRAWIAAGAPWPAGRKLDRDEKTTAVRAGRDWWSLHPLERPGVPSTQRADWAKNPIDSFILAKLEAEGMRPAPRAERHQLIRRAFFDLLGLPPSVQEVDAFVRDESPMAYERLVAKLLDSPQYGERWGRYWLDLSRYAETSGYERDQEKPGAWKYRDWVVRSINEDKPYDRFVQEQLAGDELPERNEQTVIATGFLRLGTWNDEPNDPQDYKYERLEDLVHVTSTAFLGMTVKCARCHDHKFDPIPQTDYYRLAATFWSGPIEPRKNELLGGPSREELGYDVLGWTDVTRDPPAFHLLHKGELSRPGPVVPPGVLSMIPSLDKPFAPPPAQSKTTQRRLQLASWITDPRNPLTPRVYVNRLWQHHFGHGLVSSSDNFGFNGQKPTHPELLDWLAAELISGGWKSKPIHFLMMTSQAYQQSTIHPDHESYSKQDADNRLVWRALRRRQDAEALRDAMLSVSGQLDLRVGGPSFQPVINPEALEGLSNSKTYAAPSPASEQGRRSLYMYSRRSLVHPLMTTFDFCDTTQPCGERDISVVAPQALALLNGAFVHEQSRRVADLVLASASQDRAAPVEGAWRRVLARSPSKTELAAALEHVERQSLRFRDDPEVDTLALASLCHVLINSNEFIFVD
>NC_019892.1|WP_015249890.1|8502607_8504065_+|DUF1501-domain-containing-protein
MSEKRLFPCGQSRREFLWEMGGGFAGTALASLLALDGFAPRPAMAATIDKNTLAPRAGHFPGTARNVIFLMMNGGPSQVDTFDHKPILEKYAGKPLPADKKFINSGGRKVGYLTPAFRKFRPGGQSGLMISDYFPRVRDHADKLAVIRSCHTDSHAHGSALVAMNTGKTFIGRPSLGSWAVYGLGNENQNMPGYVVILDKRGGPISGQPNWTSGFMPAGFQGTLFRPTGNPILDLKGPDYLNGSPQREQLDLLARLNQEHLDSRPGGHELAARAASYELAYRMQAEAPEAVDLSQENEKTKCMYGVGQQPTDEFGRNCLVARRLVERGVRFVQLYSGGGHLDDTWDAHTDIEANHSRHAAEVDQPISALLTDLQQRGLLETTLVVWGGEFGRMPFSEGPGEKGRNHNPYGFSMWMAGGGVKGGVAYGETDDFGFEAVQNKVHLHDVHATILHLLGLNHEMLTYFHEGRDQRLTDVAGRVVRDIIA
>NC_019892.1|WP_157579477.1|8504320_8505271_+|ROK-family-protein
MRLARDRAQVIGVVLDSSLCTMISAGLDGTIHEAGRVDFPTPDSYEALLEQISLLANTLISREGVKTLGLGISTPGLINSRTGRAMLSPNLHLTDGHSPARDLSQRLGIDCVMYQETQALCLGERMYSAPEPLDDFVMLEISTGLGVGVVMDGRLMEGHSGLAGELGHVTVALDGPLCGCGNRGCLETLATDSALTRGISEQLGHAVSLDDVKRLIHDGNTIAERELHKVCEYLAIAIAAAINLWNPSTLFVHGRLFDVRDGLFETVCDLTQRRTLAPSLADCRILRARWSKQQGAVAGAIHHLIDAHGPILDESP
>NC_019892.1|WP_015244773.1|8505554_8506979_-|IS1380-family-transposase
MATECNSTYLDFSILGHRQVLADFDGGAISSDGGALLLRQIEARTGIIRQFAACFTDHRDPDLVEHPLEHLLAQRVYGLALGYEDLNDHDDLRCDPLLATVVGKTDPTGQDRPRLRDRGKPLAGKSTLNRLELTPVGADGQSRYKKITCQTHEVERLFVTLFLQAHSRPPERIVLDLDATDDTVHGRQLGRFFHGYYKGYCYLPLYIFCGDHLLCARLRPSDIDASAGSVKSLKRIVSQIRQAWPQVKILIRADSGFCREEILRWCEDNGVDYLIGLAKNTRLTAAIATELAQARQQFEATKQPSRVFAELRYQTQKTWSRERRVVAKAEHLGKGANPRFVVTSLTVEERAAPPLYEQDYCGRGEMENRIKEQQLHLFADRTSAHTMRANQIRLFFSSIAYVLLEALRRLGLAGTAMAEAQCQTIRLKLLKIGALVRVTVRKVWVKFSSGCPYAEVFRRVHTNLARSGPLIPRC
>NC_019892.1|WP_015249892.1|8507191_8508712_-|neutral/alkaline-non-lysosomal-ceramidase-N-terminal-domain-containing-protein
MSVMGWSTWVRQARRLMVSSCCLMLAIHGVAGPSLGQSQVVERVAGKPLFRAGAFASNITPPLGEPIVGNFDTPAATHIHDELHARCIVLDDGKTRLAFAICDNVGIPREVFDAAKKLVQETTGIPSDHILMSATHSHSATTARGENALVADKELVGYQQFLVRRIADGIRQAADNLAPAQIGWGAVDVPSQVFNRRWHLKPGTPNPNPFGGEDKVKMNPGSGAATLLEPAGPTDPQVSFLSLRSLDGRPIALLANYSLHYVGGVPLGHVSADYFAVFADRMQQLLKADRLEPPFVGIMSNGTSGDVNNINFRTPGEPKAPYQKMREVADEVADAVFKAHSSITFHNWVELGAAQRELTLGVRKPTEAQRDYALKVLAKPANAKPTGPHERAYADRVLLLYDSPSEVQVLLQTFRLGDLGIAAIPFEVFTESGLEIKQKSPFKPSFTIELANGSYGYLPTPRHHALGGYETWMGTNKVEVEASEKIVKTLLDLFAGLKNNGASSTR
>NC_019892.1|WP_015249893.1|8509081_8510677_-|DUF1549-domain-containing-protein
MWIRNILFLALMLGGAAALRANFFPPRSSAPIQRPTQSPVPPELVARVDRSFRLQWTEEGLVPAKRAAELTILRRMELALTGSIPSLEEIRRFEAGPSGRRLDDRLDGLFRDRRASDYLAERLARTYVGTEGGPFLFYRRRRFLTWLSDQLLANRPYDQLIRELIAANGIWTDRPATNFVTVTYDPETKRPDAERLAGRTARAFLGVRLDCAQCHDHPFQPWKQSDFQGLAAFFGEVGTGLTGIRDRSTKFEVTNRKTGKLETIAPHVPFLPELRPADGPLRSQLARWVTDPKNAYFPRATVNRVWALMFGRALVEPIDDLPPESDLPPVLIELADDFVAHGYDLQRLIRLIVATEVFQLESATEEDVSESQEQGWSVFPITRLRPEQIVGGVIQAGSLSTIDSDSPILVRLARSLGERDFVNRYGDTGEDEFGTGCGTIPQRLLMMNGELVQNKTRDTFFNAAKRVGSLAQTDRASVEVAYLTVLTRRPTPEESAHFEARLAGTRGDKRSERMADFFWTLLNATEFSWNH
>NC_019892.1|WP_015249894.1|8510816_8512040_+|hypothetical-protein
MNNVLVLTMAGEPVDGVEFEDGDPLGGPALVDPACPEATVPQPALLRRIRDGIGSASEWLFGGFALVMGLAILSATPVLQLLSFGYLLESGGRVARTGRLRDALIGVRRAARLGSMVIGCSLVLLPLRLIASWTTSAQLVDPGGPIARRWRIGLLILTALTVLHIITSCARGGKLRYFFWPFATPRWLVRRLRRGEIYASARDEVWDFVTALRFPYYFRLGLLGFVGTMAWLLVPVTLIALGRRFPPVAFLGGFLLAIISLALPFLQMRFAAENRFAALFEYRAIRERFRRAPWAFAFAAFLTLTFAIPLYLLKIEMIPRETAWLPSLVFLGFIFPARTLTGWAYARSGRREQPRHWFFRWTSRLGMFATGLTYALIVFFTQFTAWQGIWSLYEQHAFMLPVPFLNM

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Crispr_ID: NC_019892_24

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_019892_24

9154880-9154985

Orphan

Consensus_repeat	Method
GCCTTTGCCGCGACCCGTGGTGGCGCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_019892_24

>merge|NC_019892|24|9154880-9154985|CRISPRCasFinder
GCCTTTGCCGCGACCCGTGGTGGCGCAGGGCGTTGGCCCCTTTTCCCGTTCGCGAGACCGCTTGCCAGGGGCATGGCGGCCTTTGCCGCGACCCGTGGTAGCGCAG

>NC_019892|24|23|9154880-9154985|CRISPRCasFinder
GCCTTTGCCGCGACCCGTGGTGGCGCAG	GGCGTTGGCCCCTTTTCCCGTTCGCGAGACCGCTTGCCAGGGGCATGGCG
GCCTTTGCCGCGACCCGTGGTAGCGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_019892.1\|WP_015250337.1\|9161263_9163009_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_019892.1\|WP_015250329.1\|9141105_9142014_+\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238245
NC_019892.1\|WP_015250330.1\|9143567_9148451_-\|DUF4082-domain-containing-protein	unknown	unknown	gnl\|CDD\|372556
NC_019892.1\|WP_015250324.1\|9132287_9135215_+\|hypothetical-protein	unknown	unknown	unknown
NC_019892.1\|WP_015250327.1\|9139713_9140673_+\|DUF1559-domain-containing-protein	unknown	unknown	gnl\|CDD\|284919
NC_019892.1\|WP_015250325.1\|9135572_9138524_+\|VCBS-repeat-containing-protein	unknown	unknown	gnl\|CDD\|369440
NC_019892.1\|WP_015250340.1\|9166630_9167470_-\|3-deoxy-8-phosphooctulonate-synthase	unknown	unknown	gnl\|CDD\|235363
NC_019892.1\|WP_015250341.1\|9167618_9168632_-\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|224513
NC_019892.1\|WP_015250331.1\|9148965_9149895_+\|cation-transporter	unknown	unknown	gnl\|CDD\|223131
NC_019892.1\|WP_015250326.1\|9139090_9139531_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184927
NC_019892.1\|WP_015250336.1\|9160559_9161267_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_019892.1\|WP_015250333.1\|9153154_9154660_+\|DUF1501-domain-containing-protein	unknown	unknown	gnl\|CDD\|369346
NC_019892.1\|WP_157579517.1\|9155246_9156863_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|373239
NC_019892.1\|WP_015250338.1\|9163112_9164441_+\|DUF3386-family-protein	unknown	unknown	gnl\|CDD\|371771
NC_019892.1\|WP_015250335.1\|9159309_9160431_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|214621
NC_019892.1\|WP_015250339.1\|9164569_9166279_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275091
NC_019892.1\|WP_015250334.1\|9157101_9159234_+\|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|224331
NC_019892.1\|WP_015250342.1\|9168816_9169389_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
NC_019892.1\|WP_015244411.1\|9142080_9143319_-\|IS701-like-element-ISSiac1-family-transposase	unknown	unknown	gnl\|CDD\|379252
NC_019892.1\|WP_015250332.1\|9150152_9153032_+\|DUF1553-domain-containing-protein	unknown	unknown	gnl\|CDD\|377872

Protein	Function_ID	Function_description	E-value
NC_019892.1\|WP_015250337.1\|9161263_9163009_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.67614e-39
NC_019892.1\|WP_015250329.1\|9141105_9142014_+\|cysteine-hydrolase	gnl\|CDD\|238245	cd00431, cysteine_hydrolases, Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It also contains isochorismatase, an enzyme that catalyzes the conversion of isochorismate to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of the vinyl ether bond, and other related enzymes with unknown function.	6.05313e-13
NC_019892.1\|WP_015250330.1\|9143567_9148451_-\|DUF4082-domain-containing-protein	gnl\|CDD\|372556	pfam13313, DUF4082, Domain of unknown function (DUF4082). This family appears to be a parallel beta-helix repeated region that sits between successive Cadherin domains, pfam00028.	9.18289e-59
NC_019892.1\|WP_015250327.1\|9139713_9140673_+\|DUF1559-domain-containing-protein	gnl\|CDD\|284919	pfam07596, SBP_bac_10, Protein of unknown function (DUF1559). A large family of paralogous proteins apparently unique to planctomycetes.	3.37501e-48
NC_019892.1\|WP_015250325.1\|9135572_9138524_+\|VCBS-repeat-containing-protein	gnl\|CDD\|369440	pfam07593, UnbV_ASPIC, ASPIC and UnbV. This conserved sequence is found associated with pfam00515 in several paralogous proteins in Rhodopirellula baltica. It is also found associated with pfam01839 in several eukaryotic integrin-like proteins (e.g. human ASPIC) and in several other bacterial proteins.	2.09863e-17
NC_019892.1\|WP_015250340.1\|9166630_9167470_-\|3-deoxy-8-phosphooctulonate-synthase	gnl\|CDD\|235363	PRK05198, PRK05198, 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional.	3.22819e-165
NC_019892.1\|WP_015250341.1\|9167618_9168632_-\|diacylglycerol-kinase	gnl\|CDD\|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	9.51148e-43
NC_019892.1\|WP_015250331.1\|9148965_9149895_+\|cation-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	1.0255e-81
NC_019892.1\|WP_015250326.1\|9139090_9139531_+\|hypothetical-protein	gnl\|CDD\|184927	PRK14963, PRK14963, DNA polymerase III subunits gamma and tau; Provisional.	0.00271376
NC_019892.1\|WP_015250336.1\|9160559_9161267_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.62919e-70
NC_019892.1\|WP_015250333.1\|9153154_9154660_+\|DUF1501-domain-containing-protein	gnl\|CDD\|369346	pfam07394, DUF1501, Protein of unknown function (DUF1501). This family contains a number of hypothetical bacterial proteins of unknown function approximately 400 residues long.	1.5062e-123
NC_019892.1\|WP_157579517.1\|9155246_9156863_-\|IS4-family-transposase	gnl\|CDD\|373239	pfam14706, Tnp_DNA_bind, Transposase DNA-binding. This domain occurs at the C-terminus of transposases including E. coli tnpA. TnpA encodes a transposase and an inhibitor protein, the inhibitor only differs from the transposase by the absence of the N-terminal 55 amino acids, which includes most of this domain. This domain consists of alpha helices and turns, and functions as a DNA-binding domain.	3.26424e-18
NC_019892.1\|WP_015250338.1\|9163112_9164441_+\|DUF3386-family-protein	gnl\|CDD\|371771	pfam11866, DUF3386, Protein of unknown function (DUF3386). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are about 220 amino acids in length.	6.39804e-29
NC_019892.1\|WP_015250335.1\|9159309_9160431_+\|VWA-domain-containing-protein	gnl\|CDD\|214621	smart00327, VWA, von Willebrand factor (vWF) type A domain. VWA domains in extracellular eukaryotic proteins mediate adhesion via metal ion-dependent adhesion sites (MIDAS). Intracellular VWA domains and homologues in prokaryotes have recently been identified. The proposed VWA domains in integrin beta subunits have recently been substantiated using sequence-based methods.	1.29515e-05
NC_019892.1\|WP_015250339.1\|9164569_9166279_-\|hypothetical-protein	gnl\|CDD\|275091	TIGR04267, hypothetical_protein, HEXXH motif domain. Some proteins with this domain toward the C-terminus have an N-terminal region with a radical SAM domain (pfam04055) and a SPASM domain (TIGR04085), a combination frequently associated with peptide modification. All seed alignment members, and all family members that are not fused to a radical SAM domain, have a motif HEXXH that suggests metalloprotease activity. A role in peptide or protein maturation is suggested.	0.00485876
NC_019892.1\|WP_015250334.1\|9157101_9159234_+\|HEAT-repeat-domain-containing-protein	gnl\|CDD\|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	3.73145e-08
NC_019892.1\|WP_015250342.1\|9168816_9169389_-\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00452816
NC_019892.1\|WP_015244411.1\|9142080_9143319_-\|IS701-like-element-ISSiac1-family-transposase	gnl\|CDD\|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.34197e-07
NC_019892.1\|WP_015250332.1\|9150152_9153032_+\|DUF1553-domain-containing-protein	gnl\|CDD\|377872	pfam07583, PSCyt2, Protein of unknown function (DUF1549). A family of paralogues in the planctomyces.	1.23657e-90

>NC_019892.1|WP_015250333.1|9153154_9154660_+|DUF1501-domain-containing-protein
MAGHHRQTKSGPPCGRIRRRTFLADVGNGLTGLALGSMLARDGVVRADAPEIPAWSPPDGRPQGDPKTKSVIWIFLSGGVSHLETWDPKPLLNKYAGKTYDATGLPSPFKSPLFRERSRAVVGEDRTHSEIFPLQVGFKKRGQVGVEISDWWPHLSTCVDDIAFVRSMYTTDNDHAAEFQMHHGRHKLDERQPVIGSWINYGLGTLNEDLPQFVFLGQYKDPRVREDFNADYLGPQYSGVELSLDPKNPLPFGTLAPGVLAEEQANEFALIRELNQLSSVEYPEDDQLRARIKAYELAFRMQGSVPEVVNLAQESPETQSLYGIDQEGTAIYGRRLLAARRLAERGVRFTLVYLSDYGEWDSHSKLKDLHAQSCARVDRPIAGLLKDLKRRGLTDDVTVVCCTEFGRTPGLEVRPGLTSPTGRDHHPHAFTVWFAGAGIKGATVHGATDELGFHAVESPHYVTDIHATLLHLMGLDSRKLDIPGRKRLEIDYGRPIHEILT
>NC_019892.1|WP_015250332.1|9150152_9153032_+|DUF1553-domain-containing-protein
MLASDRRARVLTVLAIGAFLLAQDAPGAEPVDYGRQVKPILKQRCYACHGALKRQANLRLDTGQAIRQGGDGGPAIEPGQGDESLLLDRVRETDAALRMPPEGAPLSAEQVAILRTWIEQGAISPADEPPETDPRKHWAFLPPVRPTVPVLRDSSWVRDPIDAFLAEEHEQRGLTPLPPAEPHVLLRRLYLDLIGLPPTRAQLHEFLADPSDASYERIVDRLLASPQYGERWGRHWMDVWRYSDWYGRRAVPDVLNSYAQIWRWRDWIVRSLNGDKGYDRMVREMLAADELAPIDDSSVVATGFVVRNFYRWNYNIWMKDNVEHTGKAFLGLTFNCAHCHDHKYDPIKHEDYFALRAVFEPLEIRHDRVAGEPDPGPYPKYDYGKAYGPITSGLVRVFDEKLDAKTFLYTRGESRNVVPDRPPVPPGMPSFLGGASFEVKPIDLPAESSYPGLRTFIRTDEMRARDAAVAKSSADLAKSLPLAHAAERALADREAKLAPDNPRAFADPFMSILAFPEPGPVASELQAARTALEAARTAVAIEEAGRNAAMAERDAIQARIAADDAKQVSASGDIKARRRAASKAERRAAAARAEIDVARGESAVAAAGGKSTAELTAASQTLTAARKARDAAQAAIANDSTAYTPLSPVYPTRSTGRRTALANWITNRANPLAARVAVNHLWRWHFGTPLVATTSDFGRNGSPPTHPKLLDWLAVELMEPTAPSVQPWSMKALHRRLVTSASYRMRSHQAGVSEADRNRGIDRENQWYWHFPASRMEAEEVRDGLLHVAGALDSTLGGPDIDFAQGLTSARRSLYFTHHGEARMTFLELFDAPDACDAYKRSTSVVPQQALALVNNEWLLALSRTLADRLWNESELSTGSEPSRVETFIIASFEQILTRLPTTRERELAGAFLAKQASLLARLSDPSGSAANSKDDPEARARRDLVHALFSHNDFVTIH
>NC_019892.1|WP_015250331.1|9148965_9149895_+|cation-transporter
MELPPEHATPQAQPSPNPAERGMRAAMTGLGINAALVVIKLTAGILGHTYALVADAIESSADIFSSLIVWGGLRITTRPPDEDYPYGYGKAETLAAAVVSLMLIGAALGIAIAAVGEIVTPHHTPAPFTLVVIAVVVVVKEILSRKVLEVGQETGSTAVKADAWHHRSDALTSAAAFIGIGVALWGGPGWESADDWAALVAAAIIAINGLLLLRPAIRDLMDRMPEGLPAEQIAAAARSVAGVQAIEKLRVRRLGTEYFVDLHVQAEPTLPLRDAHILSGKVKGAIRSEFPHVAGVLVHMEPFEKSMGS
>NC_019892.1|WP_015250330.1|9143567_9148451_-|DUF4082-domain-containing-protein
MIFREMPRAFCSIPHASRRARGGRGRLEFEVLEDRTLLASNPIVAENLLPGNPASEWDVSGAGDPTLQGFATDISVDHGQTVTFKIDDTTGASYHIDVYRMGYYGGLGARKVATISASATLHQVQPAGLSDPTTGLLDCGNWAVSASWAVPASATSGVYFARLVRDDTGGASQIPFIVRDDEGHSDLLYQTSDATWEAYNNYGGNSLYEGSSSFGTRAVKVSYNRPWNTRATTGGLGETNWFFWAEYPMVRWMEENGYDVSYFTDVDSDRLGSEILQHKVFLSVGHDEYWSGAQRTNVEVARDAGVDLAFFSGNEVFWKTRWETSIDGSGTPYRTLVCYKETHADAKIDPLTNVWTGSWRDPRFSPPADGGRPENNLTGTIFTVNQGAGGDFGTAIQVPAADALLRFWRNTSIATLQPGQTATLANGTLGYEWDEDLDNGARPAGLIQLSSTTENVPQRIQDYGNDFGPATATHSLTLYRADSGALVFAAGTVQWSFGLDGTHDGQATVPDPRMQQATVNLFADMGVQPGTLQPGLVPATASTDTARPTSIITSLAAGTLLQSGVPITISGTATDTGGGIVAAVEISTDGGLTWHRATGRTSWSYSWIPTAGGATHIRTRAVDDSANQEIPTAGVPVTVSAPSSLWNASVTPTDLYENDTHAAELGLKFTSDVAGSINGVRFYKGPSNTGTHVAHLWTSTGTLLASATFTNESASGWQQVSFSTPVTIAANTTYIVSYFAPVGQYAASSNYFSNSGFDSAPLHTPSSAAGGGNGVYLYGSSGGFPTSTYNGTNYWVDPLFTASGTNTTPPTVTSSSPAANATGVSTATAITATFSEPVQAGSVVMTLTGPGGAVSGSLAYNNATNTATFTPAAALAVQTTYVVNVSGAKDQANNVMTSVSWSFTTAATAGSPSSLWNAAVTPAIGSVNDTHAVELGLKFTSDVAGTINGVRFYKGPSNTGTHVAHLWTSTGTLLASATFTNESASGWQQVSFSTPVSIAANTTYIVSYFAPVGEYAANSNYFSSSGFDNAPLHAPSNAAGGGNGVYLYGSSGGFPTSTYNGTNYWVDPLFTASGTNTTPPTVTSSSPAANATGVSTATAITATFSEPVQAGSVVMTLTGPGGAVSGSLAYNNATNTATFTPAAALAVQTTYVVNVSGAKDQANNVMTSVSWSFTTAATGTTSGLVAAYGFNEGTGTTVTDVSGHGLNGVIVNATWTTAGRFGDALSFNGTNAMVTVNENSLLDLTNGMTLEAWVKPVALNGWTTTILKERPGGLAYSLYASDNVGRPPAGYINVSGTDSSVVGASALALNTWTYMTATYDGAAMRLYINGTLVQTRSLAGTIITSNNALRIGGNTIWGEYFNGLIDEVRVYNRALAPSEIQVDMNTPIGGGSGALMATAAPAVSSASAPLTPAAMAPLVTEAVARWQDALPAGTDLSVLAHTPIRIADLPGTQLGWTGDGAIWINQNAAGYGWFVDPTPQNDSEFTQPGDQGEQGRIDLLTVLAHEMGHVLGFGHEAEGVMAEALGPGVRRLPGSPLSHDEALASLAQTDHGDDDLRIPMDDPTLTQLASELIQARANRSRLVVNQTASFLDPKLLSTVVSSKRQPPQSSVLDPFQAGIRGFRTDVS
>NC_019892.1|WP_015244411.1|9142080_9143319_-|IS701-like-element-ISSiac1-family-transposase
MPGIIEFPKLVEAALTQHGDLFANECQRRHFAEYLTGLFVADRKTVLGIHDEFAQTTDQSCLNRFLTAAQWDPETLNDRRLEQLQKEPSTRYSVQGVIPIDNTLVDRDGMLIPDANWFWDHTEERNKIAQDYLFVNYVCTSGKHYPLEFRLFRKQEVCEALDEPFRNHTALCCELIDWVCERGIPGDFAMDCYFTNAEVLNHIDGKQDRLGRPHGYVGDLKTNRKLEWKGGILKANELAASIPVEDRKAMRIGDRRQWYFTVTVRIPGVNHKVRIVILWHYRNDGTCCKILVTNRITWEVSRIVRVYRHRWTGTETFHRDGKQQLGLGDCQLRDVQGQTRHMYLVMLAYSLLMSELKQGRAKEWALHRLMTIGEACRAMTREALRTTLSWAIEQVTQFEQPYEHVVAQLGLS
>NC_019892.1|WP_015250329.1|9141105_9142014_+|cysteine-hydrolase
MDPETSRREFLTTSITAGAVVAMLSDLSPLSAQSASKDSEQHGSRSPSSLHIKPRYYRWHVDPGVEWVETNTAHAALDWTIPLSQAAIVLVDVWDHHYLLDTEARAEAIIDDKLVPLLTACRAAGLPIIHAPSPAQARPHPNWVNLVGETEVTPKREDWPPAEFRSKSGQYQPYGRPNEPRQPELNKLGAERKLHPKVQPLAGEPVIATGEELHRYCKRHGILFLFFAGFNTNACILVRDYGTLAMNQRGYEVIVVRDCTTGMESSETQSALSQTRGAILFLEMFGNTSVTSDEIIAGLPQA
>NC_019892.1|WP_015250327.1|9139713_9140673_+|DUF1559-domain-containing-protein
MRHRSRRGFTLIELLVVIAIIAVLIALLLPAVQAAREAARRSQCINNLKQIGLGVMNYESVNMSLPPGKKGCCFGTWTVFVMPFLEQGAMYNSWNFIAGPDNDVGGGMYRYSGVGNSTVTHNRINAYTCPSDSPQVPSGNINSHSYAFNYGNTGNGQQVTLNGVAFNGAPFSDLYPPGAPNNGSTTAAWGTRGLRDLTDGTSNTILAAEVIQGQGLDLRGFTHWGDASGFETYLAPNSTLPDCIYTIGYCKYPFGTNPPCQESTTTCPNMFAARSRHPGGVNVAMGDGTVKFIKNTVSLMTWRGLGSTQGGEIISADAY
>NC_019892.1|WP_015250326.1|9139090_9139531_+|hypothetical-protein
MRTMQKRIQFSSVILLTALGGCEGGQGDDLPHQAVSGTVTLDEQPLAHGFIQFQPMGSEGVAAGGSVTDGKYAIERLQGPTPGEYKVLISSSSAPAAATDTPPPPPGAPTAPRPDPIPAKYNTASKLTAKVEAGKANSIDFPMKSK
>NC_019892.1|WP_015250325.1|9135572_9138524_+|VCBS-repeat-containing-protein
MPRRLGVAAFVLLIGLVLAKTGAWAVDSWRIRTVLDRARQSVAHGQFREAQADLEWIQGRRPRDGEPAYLLGVCAAGLGQTDKALEAWALVPDRSPLKGTAALRRGRVAIDCGRFLVAEEALTSAIRHGGEQAIEARSLLLRLLWREARFGEVANLIEDQWRELARTGQLSTAAAIDLLSGHLALDLETFPIDEVVRELQVAAIEAPGDDRVRVGLARWALRAGRHDEAGTLLSDCGSPEHADPVIWHARLDWARATGRVNEARQALAHLPASPFTKTDLLTLRAWLAAQGNDNTAERAALDELVALDPSDLTALERLAELVHQAGDLERAARLRTTKTRLDSAKFRYQTHLKNGDLATRPLEMYQLADELGRRFERMALLTLAGRKAPADPAVRKALALPASPGPPPLASRPGQTLADLLAANLVTKKGEERPKPPGPTPLVPRFIDAAESVSLRFAFDNGATSICQLPEVMSGGVGLLDVNGDGYLDVLALQGGSFPPRSNQRHGGDRLFLNRSNGTFEDITDRSGLSVPSEKPQGYSHGVAVGDYDGDGHADLFITRWRGYALYRNRGDGRFDDVTEQAGLGGDRDWPTSAAFADLDGDGDLDLYVCHYLKWDAEHPRLCPNAAGTGYLSCDPRHFKALPDHLFRNDNGRFVDVTQEAVPADIDGRGLGVVVADLDGDGRVDLFVANDGTANYLLRNLGGFRFEEVALTAGVACNAGGSFQAGMGTAVGDLDGDGNPDLFVTNFYGESTTYFSNLGQGLFADRTAAIGLAAPSRSVLGFGVALFDANNDGFPDLVTANGHVNDSRPAFPFAMPTQLLLGDRSGRLTEVTGTAGAGWSVPRIGRGLATGDLDNDGRIDVVVIDQAGPLAVFQNRTEKAGHFLTLGLSGAPSNGDSVGAVVTVKAGGRAHHAWRVGGGSYLSASDSRLHFGLNASTHADEVVVRWPSGRLDRHQNLTADSGYLLREGSLSPQPLPGFSPAVR
>NC_019892.1|WP_015250324.1|9132287_9135215_+|hypothetical-protein
MDVPLWQRRWWQATATGFLAMLLICGGFLPRMGTHSGGAPVPTDPDPRTLELGRPSDLPLPSRISVAQFEEKLFTFLNERKYVELGWRRDKSVRDAGPYLEGRSFGTHPAVRVYYSPGVMRWLLNGRSGTIPDGEMIIKEQYPAPAIRHQATLESDLPYSLESWTVMVKDAAGSHDGWFWSNPAKGQRVVDNHRYPFADPISGFGLACIRCHAATQSPGAEPSHPANEFTFAALRNIEGFPGTPLTFKTDDSWRRGAKEEKTEVVANPTDQAPRPEPSRPSVGFPSFFDAIKPVDRSQLSVLPPVTHDWVVSSREQGQEFLTSNQCMSCHAGLLAPFGPTMFVPTGASAEYGAKGWDVSPYGEWRWTPMGLAGRDPIVFAQIESEVKSLCKQFEAEPDRAGKLCATLADTCMRCHGSMGKRQFAIDHPDASSFSVDHIHEVADPAAHLGHGNAKYGALARDGVGCVVCHRMQPRPQPASDHRPYLQYFLETSNTGNFHLGKKGEIYGPFKDDEIASYAMEHATGLKPKHNAFLKSSQLCASCHTVVLPNVDRPLDLANSSEHADELTRGEVVPEFRKFHHHVEQATYLEWLNSEYENEINTQNPRAKSCQDCHMSRGLKDEKHGIDIAQLQTKIAVIQDTTYPEAENLVASDRLKVRSRETGFRRHNFSGLNAFLLEMFNQFDDVLGVPKADYMSGSTQGIDHAVEHMAQTARDDVASLAVAADWQGPNRLTARVVVANKVGHRFPSGVGFRRAFLELAIVETAKAPGEPERTVWASGLTNDQGVLLGADGQPLPTEFFDRDPGTGRQRFQQHHEIITSPDQVQVYETLLHDAKGEFTTSFVRSCATVKDNRLLPRGWRPEGPGPALTGRYLKATHPGPGASEDPRYQDGSGSDEVTYRIELPGSIDPARLEVRATLYYQAIPPYFLRNLFETAPDGPATRRLHHLTSQLNLKGTAIEDWKLRITAATCAVKAQP
>NC_019892.1|WP_157579517.1|9155246_9156863_-|IS4-family-transposase
MDKYRKAVPNQQISWSPEGADVNSQGRKPLSLPRTFVQNPEFPPAFFGQSGIVNASLDPPVGLTARGKVPWLARMLIMSPTLTDPEAWAQANFAGADLGDKRRETRLIRLATQIAVDSSASLPKATGNWDDLRAAYRLLDSSAVNFRAIAEPHWRSIRETSPEMALILDDTTEIDFGCTRQIQGVGPVGTGTGQGFMIHSGLMVSHKDEVVYGLAGQILFHRKPVPKGESRTQRRKRDRESEVWGKLIELIGSPPQNTRWVHVMDRGSDDFEVYCRAQRQGVDWVGRVKSLHRRVQGADGLERPLQEELESVPQAGCFTLKLRSRPGLPARTAKLTVTFVRATMLVPRQPADSLKGLDPQPIAQYVVCVREVDPPASVKEPIEWVLYTSLEVACLEDALRIISYYEKRWLIEEWHKALKSGCSAADHQLKASHRLEALTGLLSVVAVRLLQLKGIARSEPERPAIEAAPPKYVAVLRAFRRTTEALPWGTYQFFRELAKLGGFLGRKGDGEPGWQTIWRGWMKLQAMVQGAELDLRLE
>NC_019892.1|WP_015250334.1|9157101_9159234_+|HEAT-repeat-domain-containing-protein
MLAKTKSKVPWIATLIAFVSTIMILMTAAANRGFAVQDPAPPKEEPKSTTAAPTTNRGAAPTRRPAKQGILDLEAPIMQAELILVVRLVDMTESKLVYGGKTEVVTQQFRFEPVRTIKGIFARDSLLLTGQDLGIQQFAGGAERLEPGQLLLLLLGRQGPGYFNCNRAVSLEQSIPRLRDQADPLLAAVEALITVTQKQDRAAKVATLLSALGKAKDRDAAPLLLSLRRRALIGAQTPNALVIASRFLDDPSPEIREVTIKTLAALLEADYLQQGELRERAVKTIVAALAATGPDLSVRVAAFDALGAAGESARRVEPALEWLRADRAAATFAEHGARLRAIGRSGRTDQSDAIEAYLDQLPLDAPAEIQTAAGQALGVLAPQEAARRLVKRLMSKSDAGLGITDELALLGELPRDMAAPALVEASARLENYGEQLAFATACVKVADPRLNLALSGLLNPQFGDVRWQASEALRRIDTNEAASLLSPHLKEEANLLRKLQLAEFLGRHGFREGYPYAIEHMSAPELQDAAVEALAAIQEPKAVPELRKIWESSHDLGWNAAAIRALGRLGQADIAPQLLELAGRKNPLTAPALIALGDLQIIKALPLVLDGLGSRNDPVVIAAARAAGKLLAGPEARSNEVRDRLAALVADPDASQAVRGTALESLVALNDPRLDTALIAAVQDGSLEDSALLLRIEKLLATRKVKLNPQ
>NC_019892.1|WP_015250335.1|9159309_9160431_+|VWA-domain-containing-protein
MKRILTIAAFAVSGWLGLLGVAEAKGPAVQIALLLDTSNSMDGLIDQAKSQLWSVVNEFIHAKRDGRPASIEVALYEYGNDNLPAQEGFVRMVVPLTDDLDMVSEKLFALKTRGGSEFCGQVIRDATGQLTWSRSDDVYKAIFIAGNEPFTQGSVDYHGACRGAIKKGIIVNTIFCGPNSEGEQTGWSAGAVLADGRYMSIDHNHKVVTIPCPQDGEIARLGFDLNKTYIPYGRMGREGQSRQAAQDANASTVSPSVLASRAVSKSSLNVYCNDTWDLIDAIKTGKCKLDDLKDDDLPEDLRKLSKAERLACVNDKCAQRETVQKRILSLHREREAFLAAERKKQAAANEETLDTVILKAVREQAARANIRFE
>NC_019892.1|WP_015250336.1|9160559_9161267_+|response-regulator-transcription-factor
MSSKKVLVIEDDPAIRRGLIDALAFAGYATLEASDGLVGCRTALDADCDLLLLDLVLPGRDGLDILRAVRLARPTLPVIVLTARASEDDRVRGLSSGSDDYIIKPFSIRELLARVEAVLRRSPGRPPGIRRVKFIGGLADLERREVRFDNGERSDLSERENQLLLYLASHTERVISREEILAQVWGLDPAGITTRTIDMHVARLREKLRDDSVRPRIILTVRGLGYMLHAGGVTP
>NC_019892.1|WP_015250337.1|9161263_9163009_+|HAMP-domain-containing-histidine-kinase
MRKHPGWIWLAYGLCVTLAALAMTRVGAMALELERAESRIRRQAALDEDLQLALWRMDSALAPLIAEEGMRPYFTYSSFYPTERAYTHMLEAVNKGDVLVASPLLTYTSPRILLHFQFGPDGRLNSPQVPEGNMRALAESRFLPPERLDAAARQLALLRGLVSEPAMAMCCPTEPAPSIASKDIFSMFPDQTATDQARQSRSSTEYMMRFLNKTKAQTVAPEPPLATTVPVLQAPMEAAWIDKSLILGRRVRVGPTTFLQGCWLNWEAIRAELLGSVVDLVPNATLEPVQADDQAPTRRLAALPARLVMRPAEADVPTSWSPIRLALGITWACLILTTGAVALLLGGALSLSERRGTFVSAVTHELRTPLTTFQLYTEMLAEGMVSDPETQASYLQTLRTESERLGHLVENVLSFACIERGRSIDRRDRLAVADLSVRIQPALAARADRGGMELVVDHDLPDVRIRTDVSLVEQILSNLVDNAAKYANSSGDRRIELKFAVAHAKLTVTVRDHGPGLPERAIRRLFRPFSKSAHDAAHSAPGVGLGLALSRRLARALGGDLRLGQNGPDGVGFVLTLPIEA
>NC_019892.1|WP_015250338.1|9163112_9164441_+|DUF3386-family-protein
MLTLLPFVMTVCAHFLFIRIGPAAEAGQAAEVYFSEQAEAGDPKFVTKVAGTKLWVQTAPRSFKPLEVREGVDRLRASLPSSETLSVVGACEYGVLARPKEVPFLLRYYPKAIAGDPGELNRMTAREEIPLEIMGKLEGDKIHLVLLKQGKPVPGVVFHAVDADLTESEATAGPDGTAVWTPPAPGPYSIYARDTTKRSGEIGGKSYEEIREFATLAFTWPLGSRQADPEAVSLFEQALAARAQWKDFPGFSAQLAGESNGRPFSGTVRFLADGKVELKVDDPVARPWLKEQFESLAMHRRAEAADNSAGPEDKPVLRFADDREDHPLGRLLTFDGGRFASSYRIKDRQIRVVNRRIGPKHMTITVLDNDQNAEGKFLPHSYVVHHWDAITGGLDRVETVQERWQRIGSWDLPVSHTTSNASGGGFSVRSVTLSEHELLKAN
>NC_019892.1|WP_015250339.1|9164569_9166279_-|hypothetical-protein
MKWRLSLLAVLTCLASTWAGCDYSTTELPPAANSSIATNTEGEQVASSSESSFNDMKPTILESVISLIQTAALKPGGDNFKLAVLKLNTYFEDIPRSQFALEPTVRDYLKAAKLPEQVMAGFERTTFEMPDSRHLEDCMLYHGIATRIGGNGDDLTRVRRVFDWMVRQVQLAPAGTLAAPGLPQAQVRPYDMLLRGMATEADGGWSERGWLFMSLCRQLGVDVALLTYQPKDVEVPNTWICAALIDGKLYLFDPRLGIEIPGPGGKGVATLDEALADPEVLGRLNVPGAPAYRPSHELLAASTTKIGALLDSSPGYYAPRMLLLEKSLPGKYQTVLYRDPVDESKKFTKALGARAGEVTPWPLPLMVETMLFTSGEFVQATQHALFLFRPEFPLLYARIKQLRGELPEAVSDYMTFRFVERPLLMDRKTPMPQEVQQALDMYSTYFLGLAHLEQDDLGKDKKHLERAELFFKATLKDLPAPGPRQPYYHMFRWGAQSNLGRLNEAQGDLESAVAYYSEADPTAQHQGNLLRARDLILNDPFSPLPAPLSSAPASTPNAPPEFLKRSEAN
>NC_019892.1|WP_015250340.1|9166630_9167470_-|3-deoxy-8-phosphooctulonate-synthase
MASLNPVSVGQVEIGRGRPLALICGPCVMEPNDLTLVIARRLVEVCGALGVPLIFKASFDKANRTSKSSYRGPGIDDGLKVFERVKAETGLPVTTDVHESQQAAPIAKVVDLLQIPAFLARQTDLLEAAAATGRPINVKKGQFMAPWDMNNVVAKITSQSRSGVLLTERGTTFGYGRLVNDFRAIPQMQATGAPVVFDATHSVQLPSAGEGGTVTAGEREMVPYLAKAAVAAGCDALFLEVHPRPDEALSDGPNALRLDDLAGLLRTCLRIRAAISVDE
>NC_019892.1|WP_015250341.1|9167618_9168632_-|diacylglycerol-kinase
MTEGVEPGLAIGHEARSGAIRSNGEGVGSDQPWVGIAANPGSGRGRGRRQVERLQAELERLGLSTRVAWSLPDRAVLVAESAADPHCRCLVAAGGDGTVAALVNERPAVPITVLPAGTENLFARHFRLDRNPARLASIIAAGAVAQLDLGLTATRRFTLMAGIGFDADVVARHHSTRVGRAGVARPTHRGAYVESVLRSSLEYRFPRLTVSITDPGAEETLVGATAFIFNLPRYALGLPFAPTARGDDGWLDLVVFRNAGPLQSLRYLWMVLRGIHLDRDGVEHRRFRRVVVTSAETVPVQLDGDPGGSVSPEGHPDGVWSVEVLPNALEVLVPDGG
>NC_019892.1|WP_015250342.1|9168816_9169389_-|hypothetical-protein
MSTAGKVLVVLVLLLLPVWIILVSAVATLNMEWTQALAKQTQQIETLEADVAKNQRAIADFQDKITLEQLASEEEQTVLRSKLADVERAKAEVIEVQTSVQVQLATLQQAVAKAQVARVDRDKEQQNETAGLAAARASVDELKAANSALLNELTQLREEFKSLLESNKTVVERIIKGKTRQVVRPASFVR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_019892_10	10.1\|4988044\|51\|NC_019892\|CRISPRCasFinder	4988044-4988094	51	NC_019892.1	5291138-5291188	2	0.961
NC_019892_18	18.1\|5369118\|49\|NC_019892\|CRISPRCasFinder	5369118-5369166	49	NC_019892.1	5261956-5262004	2	0.959
NC_019892_21	21.1\|8473194\|31\|NC_019892\|CRISPRCasFinder	8473194-8473224	31	NC_019892.1	8473224-8473254	1	0.968
NC_019892_21	21.1\|8473194\|31\|NC_019892\|CRISPRCasFinder	8473194-8473224	31	NC_019892.1	8473254-8473284	2	0.935

1. spacer 10.1|4988044|51|NC_019892|CRISPRCasFinder matches to position: 5291138-5291188, mismatch: 2, identity: 0.961

tctagccaggggtgaaacccctggaaacaggatgaactcaaatcaatatga	CRISPR spacer
tctagccaggggtgaaacccctggaaacaggatgaactcaaattagtatga	Protospacer
*******************************************.*.*****

2. spacer 18.1|5369118|49|NC_019892|CRISPRCasFinder matches to position: 5261956-5262004, mismatch: 2, identity: 0.959

ttctagccaggggtgaaacccctgggaaaggttcgacatatgagtgctc	CRISPR spacer
ttctagccaggggtgaaacccctgggaaatgttcgacatatgagtgttc	Protospacer
***************************** ****************.**

3. spacer 21.1|8473194|31|NC_019892|CRISPRCasFinder matches to position: 8473224-8473254, mismatch: 1, identity: 0.968

gggctacggcggattcggttacggaggcctg	CRISPR spacer
gggctacggcgggttcggttacggaggcctg	Protospacer
************.******************

4. spacer 21.1|8473194|31|NC_019892|CRISPRCasFinder matches to position: 8473254-8473284, mismatch: 2, identity: 0.935

gggctacggcggattcggttacggaggcctg	CRISPR spacer
gggctacggcggatttggctacggaggcctg	Protospacer
***************.**.************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_019892_22	22.3\|8474068\|24\|NC_019892\|CRT	8474068-8474091	24	NZ_CP019319	Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-7, complete sequence	21134-21157	3	0.875
NC_019892_22	22.5\|8474158\|24\|NC_019892\|CRT	8474158-8474181	24	NZ_CP019319	Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-7, complete sequence	21134-21157	3	0.875
NC_019892_22	22.3\|8474068\|24\|NC_019892\|CRT	8474068-8474091	24	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	221011-221034	4	0.833
NC_019892_22	22.5\|8474158\|24\|NC_019892\|CRT	8474158-8474181	24	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	221011-221034	4	0.833
NC_019892_16	16.31\|5293727\|35\|NC_019892\|CRT,CRISPRCasFinder	5293727-5293761	35	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	683736-683770	5	0.857
NC_019892_16	16.31\|5293727\|35\|NC_019892\|CRT,CRISPRCasFinder	5293727-5293761	35	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	299546-299580	5	0.857
NC_019892_2	2.56\|478115\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	478115-478149	35	NZ_CP054618	Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence	102996-103030	7	0.8
NC_019892_2	2.56\|478115\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	478115-478149	35	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	655632-655666	7	0.8
NC_019892_2	2.106\|481723\|37\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481723-481759	37	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	716189-716225	7	0.811
NC_019892_2	2.149\|484806\|33\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	484806-484838	33	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	635685-635717	7	0.788
NC_019892_14	14.9\|5269582\|28\|NC_019892\|CRISPRCasFinder	5269582-5269609	28	NC_019691	Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence	33251-33278	7	0.75
NC_019892_16	16.31\|5293727\|35\|NC_019892\|CRT,CRISPRCasFinder	5293727-5293761	35	NC_008826	Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence	395635-395669	7	0.8
NC_019892_16	16.31\|5293727\|35\|NC_019892\|CRT,CRISPRCasFinder	5293727-5293761	35	NC_008826	Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence	427705-427739	7	0.8
NC_019892_17	17.41\|5321015\|35\|NC_019892\|CRT,PILER-CR,CRISPRCasFinder	5321015-5321049	35	NZ_CP049358	Deinococcus wulumuqiensis R12 plasmid unnamed1, complete sequence	290126-290160	7	0.8
NC_019892_17	17.41\|5321015\|35\|NC_019892\|CRT,PILER-CR,CRISPRCasFinder	5321015-5321049	35	NZ_CP031159	Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence	262178-262212	7	0.8
NC_019892_2	2.47\|477464\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	477464-477498	35	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	360803-360837	8	0.771
NC_019892_2	2.47\|477464\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	477464-477498	35	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	150681-150715	8	0.771
NC_019892_2	2.107\|481796\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481796-481829	34	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	381922-381955	8	0.765
NC_019892_2	2.107\|481796\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481796-481829	34	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	244904-244937	8	0.765
NC_019892_2	2.141\|484235\|37\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	484235-484271	37	NZ_LT969519	Pseudomonas aeruginosa isolate RW109 genome assembly, plasmid: RW109 plasmid 1	110356-110392	8	0.784
NC_019892_15	15.19\|5279628\|35\|NC_019892\|CRISPRCasFinder,CRT	5279628-5279662	35	NZ_CP035424	Leisingera sp. NJS204 plasmid unnamed7, complete sequence	41687-41721	8	0.771
NC_019892_15	15.19\|5279628\|35\|NC_019892\|CRISPRCasFinder,CRT	5279628-5279662	35	NZ_CP038236	Leisingera sp. NJS201 plasmid unnamed2, complete sequence	13169-13203	8	0.771
NC_019892_15	15.19\|5279628\|35\|NC_019892\|CRISPRCasFinder,CRT	5279628-5279662	35	NZ_CP015043	Rhodovulum sp. P5 plasmid pRGUI04, complete sequence	48302-48336	8	0.771
NC_019892_15	15.70\|5279629\|35\|NC_019892\|PILER-CR	5279629-5279663	35	NZ_CP035424	Leisingera sp. NJS204 plasmid unnamed7, complete sequence	41687-41721	8	0.771
NC_019892_15	15.70\|5279629\|35\|NC_019892\|PILER-CR	5279629-5279663	35	NZ_CP038236	Leisingera sp. NJS201 plasmid unnamed2, complete sequence	13169-13203	8	0.771
NC_019892_15	15.70\|5279629\|35\|NC_019892\|PILER-CR	5279629-5279663	35	NZ_CP015043	Rhodovulum sp. P5 plasmid pRGUI04, complete sequence	48302-48336	8	0.771
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP021025	Rhizobium sp. TAL182 plasmid pRetTAL182a, complete sequence	136116-136151	8	0.778
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP013600	Rhizobium sp. N741 plasmid pRspN741e, complete sequence	241932-241967	8	0.778
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP013504	Rhizobium esperanzae strain N561 plasmid pRspN561d, complete sequence	241932-241967	8	0.778
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP013510	Rhizobium sp. N1341 plasmid pRspN1341e, complete sequence	240373-240408	8	0.778
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP013521	Rhizobium sp. N113 plasmid pRspN113d, complete sequence	244620-244655	8	0.778
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP013494	Rhizobium sp. N6212 plasmid pRspN6212d, complete sequence	238738-238773	8	0.778
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP013512	Rhizobium sp. N1314 plasmid pRspN1314a, complete sequence	132049-132084	8	0.778
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP013594	Rhizobium sp. N871 plasmid pRspN871d, complete sequence	241932-241967	8	0.778
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	MF919536	Mycobacterium phage TipsytheTRex, complete genome	25062-25096	8	0.771
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	MG099947	Mycobacterium phage Ph8s, complete genome	24534-24568	8	0.771
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	MH020237	Mycobacterium phage Jsquared, complete genome	24774-24808	8	0.771
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	MN585989	Mycobacterium phage Superchunk, complete genome	24105-24139	8	0.771
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	KM197169	Mycobacterium phage Piro94, complete genome	25825-25859	8	0.771
NC_019892_2	2.25\|475890\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	475890-475924	35	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	3950221-3950255	9	0.743
NC_019892_2	2.56\|478115\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	478115-478149	35	NZ_CP024308	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3a, complete sequence	321759-321793	9	0.743
NC_019892_2	2.63\|478623\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	478623-478656	34	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	20924-20957	9	0.735
NC_019892_2	2.63\|478623\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	478623-478656	34	NC_015970	Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence	47584-47617	9	0.735
NC_019892_2	2.96\|480999\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	480999-481032	34	MH617729	Microviridae sp. isolate ctbh687, complete genome	1212-1245	9	0.735
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP019187	Salmonella enterica subsp. enterica serovar Pomona str. ATCC 10729 plasmid pATCC10729_01, complete sequence	94453-94487	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP024678	Citrobacter freundii strain UMH16 plasmid pUMH16, complete sequence	45820-45854	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP030220	Salmonella enterica strain SA20021456 plasmid pSA20021456.1, complete sequence	13029-13063	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP024682	Citrobacter freundii strain UMH14 plasmid pUMH14_2, complete sequence	20147-20181	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP024674	Citrobacter freundii strain UMH19 plasmid pUMH19, complete sequence	45963-45997	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP011595	Klebsiella oxytoca strain CAV1099 plasmid pKPC_CAV1099, complete sequence	77087-77121	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	CP053329	Salmonella enterica subsp. salamae serovar 60:z10:z39 strain 2011K-1889 plasmid unnamed1, complete sequence	25188-25222	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP047309	Citrobacter freundii strain L75 plasmid pCf76, complete sequence	21910-21944	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NC_019093	Escherichia coli plasmid pLST424C-61, complete sequence	23659-23693	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP030210	Salmonella enterica strain SA20044414 plasmid pSA20044414.1, complete sequence	13921-13955	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP026394	Klebsiella pneumoniae strain KPNIH48 plasmid pKPC-e937, complete sequence	20894-20928	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP046347	Citrobacter portucalensis strain FDAARGOS_738 plasmid unnamed1, complete sequence	46682-46716	9	0.743
NC_019892_2	2.102\|481435\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	481435-481469	35	NZ_CP044100	Citrobacter werkmanii strain FDAARGOS_616 plasmid unnamed1, complete sequence	49430-49464	9	0.743
NC_019892_2	2.141\|484235\|37\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	484235-484271	37	NC_018580	Gordonia sp. KTR9 plasmid pGKT2, complete sequence	62776-62812	9	0.757
NC_019892_2	2.149\|484806\|33\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	484806-484838	33	NZ_CP025114	Bradyrhizobium sp. SK17 strain CBNU plasmid unnamed, complete sequence	14429-14461	9	0.727
NC_019892_2	2.149\|484806\|33\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	484806-484838	33	NZ_CP025114	Bradyrhizobium sp. SK17 strain CBNU plasmid unnamed, complete sequence	277174-277206	9	0.727
NC_019892_2	2.149\|484806\|33\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	484806-484838	33	NZ_CP043960	Streptomyces tendae strain 139 plasmid unnamed1, complete sequence	309707-309739	9	0.727
NC_019892_2	2.153\|485091\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	485091-485124	34	NZ_CP024423	Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence	163282-163315	9	0.735
NC_019892_2	2.153\|485091\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	485091-485124	34	NZ_CP020441	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed1, complete sequence	160994-161027	9	0.735
NC_019892_2	2.153\|485091\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	485091-485124	34	NZ_CP044080	Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence	142776-142809	9	0.735
NC_019892_2	2.153\|485091\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	485091-485124	34	NZ_CP031079	Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence	147304-147337	9	0.735
NC_019892_2	2.154\|485161\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	485161-485195	35	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	2166024-2166058	9	0.743
NC_019892_2	2.154\|485161\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	485161-485195	35	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	1070192-1070226	9	0.743
NC_019892_14	14.2\|5269513\|32\|NC_019892\|CRT	5269513-5269544	32	NC_048053	Dickeya phage vB_DsoM_JA29, complete genome	70703-70734	9	0.719
NC_019892_15	15.3\|5278458\|36\|NC_019892\|CRISPRCasFinder,CRT	5278458-5278493	36	NC_010865	Sinorhizobium meliloti plasmid pSmeSM11b, complete sequence	144926-144961	9	0.75
NC_019892_15	15.3\|5278458\|36\|NC_019892\|CRISPRCasFinder,CRT	5278458-5278493	36	NZ_CP021216	Sinorhizobium meliloti RU11/001 plasmid pSmeRU11d, complete sequence	53557-53592	9	0.75
NC_019892_15	15.19\|5279628\|35\|NC_019892\|CRISPRCasFinder,CRT	5279628-5279662	35	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	296158-296192	9	0.743
NC_019892_15	15.47\|5281676\|35\|NC_019892\|CRISPRCasFinder,CRT	5281676-5281710	35	NZ_CP018468	Xanthomonas vesicatoria strain LM159 plasmid pLM159.1, complete sequence	192705-192739	9	0.743
NC_019892_15	15.54\|5278459\|36\|NC_019892\|PILER-CR	5278459-5278494	36	NC_010865	Sinorhizobium meliloti plasmid pSmeSM11b, complete sequence	144926-144961	9	0.75
NC_019892_15	15.54\|5278459\|36\|NC_019892\|PILER-CR	5278459-5278494	36	NZ_CP021216	Sinorhizobium meliloti RU11/001 plasmid pSmeRU11d, complete sequence	53557-53592	9	0.75
NC_019892_15	15.70\|5279629\|35\|NC_019892\|PILER-CR	5279629-5279663	35	NZ_CP035710	Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence	296158-296192	9	0.743
NC_019892_15	15.98\|5281677\|35\|NC_019892\|PILER-CR	5281677-5281711	35	NZ_CP018468	Xanthomonas vesicatoria strain LM159 plasmid pLM159.1, complete sequence	192705-192739	9	0.743
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1586620-1586655	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1504835-1504870	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1503857-1503892	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1574023-1574058	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1574024-1574059	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1504827-1504862	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1504180-1504215	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1504817-1504852	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1586788-1586823	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1586771-1586806	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1586751-1586786	9	0.75
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NC_008243	Chelativorans sp. BNC1 plasmid 2, complete sequence	41426-41461	9	0.75
NC_019892_16	16.17\|5292702\|35\|NC_019892\|CRT,CRISPRCasFinder	5292702-5292736	35	NZ_CP049749	Rhodococcus fascians A21d2 plasmid pA21d2, complete sequence	160665-160699	9	0.743
NC_019892_16	16.31\|5293727\|35\|NC_019892\|CRT,CRISPRCasFinder	5293727-5293761	35	NC_008759	Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence	143507-143541	9	0.743
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_MF150120	Klebsiella pneumoniae strain A64477 plasmid pKP64477d, complete sequence	24680-24715	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_KX756453	Klebsiella pneumoniae strain 1194/11 plasmid pKP1194a, complete sequence	27049-27084	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_CP014069	Citrobacter amalonaticus strain FDAARGOS_165 plasmid unnamed	30071-30106	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_CP003997	Klebsiella pneumoniae subsp. pneumoniae Kp13 plasmid pKP13d, complete sequence	27215-27250	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_CP032305	Salmonella enterica subsp. enterica serovar Braenderup strain FORC93 plasmid unnamed1, complete sequence	808-843	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_CP043513	Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed2, complete sequence	562-597	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_CP027700	Klebsiella pneumoniae strain KP30835 plasmid unnamed5, complete sequence	38676-38711	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_MK264770	Klebsiella pneumoniae strain KP89 plasmid pKP89, complete sequence	27216-27251	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_KU963389	Escherichia coli strain ECO37 plasmid ECO37P1, complete sequence	30534-30569	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_CP026758	Klebsiella aerogenes strain AR_0062 plasmid tig00000058_pilon, complete sequence	30315-30350	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	KR822247	Escherichia coli strain E0083033-2 plasmid pEc2A, complete sequence	61272-61307	9	0.75
NC_019892_16	16.72\|5296755\|36\|NC_019892\|CRT,CRISPRCasFinder,PILER-CR	5296755-5296790	36	NZ_CP030195	Salmonella enterica strain SA20080453 plasmid pSA20080453.1, complete sequence	24615-24650	9	0.75
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	NC_025025	Mycobacterium tuberculosis H37Rv plasmid pTYGi9, complete sequence	3662-3696	9	0.743
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	M65194	Mycobacterium phage L5 integrase (int) gene, complete cds	1425-1459	9	0.743
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	NC_008203	Mycobacterium phage Che12, complete genome	24486-24520	9	0.743
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	NC_022058	Mycobacterium phage Adzzy, complete genome	24249-24283	9	0.743
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	KX683423	Mycobacterium phage BabyRay, complete genome	25475-25509	9	0.743
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	DQ398043	Mycobacterium virus Che12, complete genome	24486-24520	9	0.743
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	KT381276	Mycobacterium phage Serenity, complete genome	24826-24860	9	0.743
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	Z18946	Mycobacterium phage L5 complete genome	24477-24511	9	0.743
NC_019892_17	17.34\|5320516\|35\|NC_019892\|CRISPRCasFinder,CRT	5320516-5320550	35	NC_017973	Mycobacterium phage SWU1, complete genome	24432-24466	9	0.743
NC_019892_2	2.14\|475100\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	475100-475133	34	NZ_CP021372	Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence	370871-370904	10	0.706
NC_019892_2	2.20\|475533\|36\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	475533-475568	36	MN908687	Gordonia phage Skog, complete genome	91342-91377	10	0.722
NC_019892_2	2.121\|482793\|37\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	482793-482829	37	NZ_CP032695	Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence	64575-64611	10	0.73
NC_019892_2	2.144\|484451\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	484451-484484	34	NZ_CP017105	Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence	878433-878466	10	0.706
NC_019892_13	13.1\|5262311\|35\|NC_019892\|CRISPRCasFinder	5262311-5262345	35	CP011075	Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence	287757-287791	10	0.714
NC_019892_13	13.1\|5262311\|35\|NC_019892\|CRISPRCasFinder	5262311-5262345	35	NZ_CP011154	Bacillus cereus strain CMCC P0011 plasmid pRML05, complete sequence	442156-442190	10	0.714
NC_019892_13	13.1\|5262311\|35\|NC_019892\|CRISPRCasFinder	5262311-5262345	35	NZ_CP011152	Bacillus cereus strain CMCC P0021 plasmid pRML04, complete sequence	104725-104759	10	0.714
NC_019892_13	13.1\|5262311\|35\|NC_019892\|CRISPRCasFinder	5262311-5262345	35	CP020755	Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence	515078-515112	10	0.714
NC_019892_13	13.1\|5262311\|35\|NC_019892\|CRISPRCasFinder	5262311-5262345	35	NC_020385	Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-328, complete sequence	292825-292859	10	0.714
NC_019892_13	13.1\|5262311\|35\|NC_019892\|CRISPRCasFinder	5262311-5262345	35	NZ_CP021062	Bacillus thuringiensis strain ATCC 10792 plasmid poh1, complete sequence	146120-146154	10	0.714
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1661762-1661797	10	0.722
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	CP000663	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA02, complete sequence	47196-47231	10	0.722
NC_019892_16	16.15\|5292558\|36\|NC_019892\|CRT,CRISPRCasFinder	5292558-5292593	36	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1576748-1576783	10	0.722
NC_019892_17	17.22\|5319638\|37\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	5319638-5319674	37	NZ_CP032685	Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence	689763-689799	10	0.73
NC_019892_17	17.22\|5319638\|37\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	5319638-5319674	37	NZ_CP032690	Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence	689312-689348	10	0.73
NC_019892_2	2.69\|479047\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	479047-479080	34	LC494302	Escherichia phage SP27 DNA, complete genome	146082-146115	11	0.676
NC_019892_2	2.69\|479047\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	479047-479080	34	MH791411	UNVERIFIED: Escherichia phage Ecwhy_1, complete genome	296306-296339	11	0.676
NC_019892_2	2.69\|479047\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	479047-479080	34	NC_027364	Escherichia phage PBECO 4, complete genome	140330-140363	11	0.676
NC_019892_2	2.69\|479047\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	479047-479080	34	MH383160	Escherichia phage UB, complete genome	201422-201455	11	0.676
NC_019892_2	2.69\|479047\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	479047-479080	34	MK327931	Escherichia phage vB_EcoM_G17, complete genome	8410-8443	11	0.676
NC_019892_2	2.69\|479047\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	479047-479080	34	MK327931	Escherichia phage vB_EcoM_G17, complete genome	358559-358592	11	0.676
NC_019892_2	2.69\|479047\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	479047-479080	34	MH494197	Escherichia phage CMSTMSU, complete genome	120522-120555	11	0.676
NC_019892_2	2.69\|479047\|34\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	479047-479080	34	LT603033	Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I	88263-88296	11	0.676
NC_019892_2	2.132\|483589\|38\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	483589-483626	38	HM486077	Tsukamurella phage TPA2, complete sequence	48099-48136	11	0.711
NC_019892_2	2.132\|483589\|38\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	483589-483626	38	NC_015210	Tsukamurella phage TPA2, complete genome	48099-48136	11	0.711
NC_019892_17	17.22\|5319638\|37\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	5319638-5319674	37	NC_015057	Granulicella tundricola MP5ACTX9 plasmid pACIX901, complete sequence	430177-430213	11	0.703
NC_019892_17	17.59\|5322331\|35\|NC_019892\|CRT,PILER-CR,CRISPRCasFinder	5322331-5322365	35	NZ_CP026539	Desulfovibrio carbinolicus strain DSM 3852 plasmid pDCAR1, complete sequence	71038-71072	11	0.686
NC_019892_17	17.28\|5320078\|35\|NC_019892\|CRISPRCasFinder,CRT,PILER-CR	5320078-5320112	35	NZ_CP038637	Cupriavidus oxalaticus strain X32 plasmid unnamed2, complete sequence	44830-44864	12	0.657

1. spacer 22.3|8474068|24|NC_019892|CRT matches to NZ_CP019319 (Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-7, complete sequence) position: , mismatch: 3, identity: 0.875

gcattgcgccccaacggggccaac	CRISPR spacer
ccattgcgccccaacagggccacc	Protospacer
 **************.****** *

2. spacer 22.5|8474158|24|NC_019892|CRT matches to NZ_CP019319 (Tateyamaria omphalii strain DOK1-4 plasmid pDOK1-4-7, complete sequence) position: , mismatch: 3, identity: 0.875

gcattgcgccccaacggggccaac	CRISPR spacer
ccattgcgccccaacagggccacc	Protospacer
 **************.****** *

3. spacer 22.3|8474068|24|NC_019892|CRT matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 4, identity: 0.833

gcattgcgccccaacggggccaac	CRISPR spacer
gcattgcgccccaacgcggccgtt	Protospacer
**************** ****. .

4. spacer 22.5|8474158|24|NC_019892|CRT matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 4, identity: 0.833

gcattgcgccccaacggggccaac	CRISPR spacer
gcattgcgccccaacgcggccgtt	Protospacer
**************** ****. .

5. spacer 16.31|5293727|35|NC_019892|CRT,CRISPRCasFinder matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 5, identity: 0.857

-ctgccgtccgtggtcgtcgacgccggccagttcgg	CRISPR spacer
cccgccg-ccgtggtcatcgacgccgggcagttccg	Protospacer
 *.**** ********.********** ****** *

6. spacer 16.31|5293727|35|NC_019892|CRT,CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 5, identity: 0.857

--ctgccgtccgtggtcgtcgacgccggccagttcgg	CRISPR spacer
ccctgccg--cgtcgtcgtcgccgccggccagttcga	Protospacer
  ******  *** ******* **************.

7. spacer 2.56|478115|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054618 (Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence) position: , mismatch: 7, identity: 0.8

agcctggtgatcgtcaccggcccggggcagacggt	CRISPR spacer
agccgggtgatcgtcaccagcccggtgacgttggt	Protospacer
**** *************.****** *  * .***

8. spacer 2.56|478115|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 7, identity: 0.8

agcctggtgatcgtcaccggcccggggcagacggt	CRISPR spacer
agccgggtgatcgtcaccagcccggtgacgttggt	Protospacer
**** *************.****** *  * .***

9. spacer 2.106|481723|37|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 7, identity: 0.811

atcatcttcggcgactcggccggcacgatcatcgcgg	CRISPR spacer
agcatcttcggcaacacggccggcacgatctgccagg	Protospacer
* **********.** **************  *  **

10. spacer 2.149|484806|33|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.788

atcgcggaacgcaccgtcgtgatcgaccggacc	CRISPR spacer
ctcgcggaccgcaccgtggtgatcgccaacacc	Protospacer
 ******* ******** ******* * . ***

11. spacer 14.9|5269582|28|NC_019892|CRISPRCasFinder matches to NC_019691 (Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence) position: , mismatch: 7, identity: 0.75

tattctcacgactgctcaggttcctcag	CRISPR spacer
tattctcacaactgctcaggtgatctat	Protospacer
*********.***********  ...*

12. spacer 16.31|5293727|35|NC_019892|CRT,CRISPRCasFinder matches to NC_008826 (Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence) position: , mismatch: 7, identity: 0.8

---ctgccgtccgtggtcgtcgacgccggccagttcgg	CRISPR spacer
ggtgtgctg---gtggtcgacgacgccggccagttcgt	Protospacer
    ***.*   ******* *****************

13. spacer 16.31|5293727|35|NC_019892|CRT,CRISPRCasFinder matches to NC_008826 (Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence) position: , mismatch: 7, identity: 0.8

---ctgccgtccgtggtcgtcgacgccggccagttcgg	CRISPR spacer
ggtgtgctg---gtggtcgacgacgccggccagttcgt	Protospacer
    ***.*   ******* *****************

14. spacer 17.41|5321015|35|NC_019892|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP049358 (Deinococcus wulumuqiensis R12 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.8

acgaaatcaagtccctggtcgagcaggg----gttaaaa	CRISPR spacer
acgaattcaagtccctgctcgagcagggccgcgtc----	Protospacer
***** *********** **********    **.

15. spacer 17.41|5321015|35|NC_019892|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP031159 (Deinococcus wulumuqiensis strain NEB 479 plasmid pDrdA, complete sequence) position: , mismatch: 7, identity: 0.8

acgaaatcaagtccctggtcgagcaggg----gttaaaa	CRISPR spacer
acgaattcaagtccctgctcgagcagggccgcgtc----	Protospacer
***** *********** **********    **.

16. spacer 2.47|477464|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 8, identity: 0.771

ctcggccttgagccgttcgatcatcgcggcgagct	CRISPR spacer
ggtgccggtgagccgctcgatcatcgcggcgagtt	Protospacer
  .* *  *******.*****************.*

17. spacer 2.47|477464|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 8, identity: 0.771

ctcggccttgagccgttcgatcatcgcggcgagct	CRISPR spacer
gtggtcaacgagccgttcgatcagcgcggcgtgct	Protospacer
 * * *  .************** ******* ***

18. spacer 2.107|481796|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 8, identity: 0.765

aagaacagttcggcggctgaggctgtgtcgtagc	CRISPR spacer
aagaacagttcggcagcagaggcttcctcatgcc	Protospacer
**************.** ****** . **.*. *

19. spacer 2.107|481796|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aagaacagttcggcggctgaggctgtgtcgtagc	CRISPR spacer
aagaacagttcggcagcagaggcttcctcatgcc	Protospacer
**************.** ****** . **.*. *

20. spacer 2.141|484235|37|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LT969519 (Pseudomonas aeruginosa isolate RW109 genome assembly, plasmid: RW109 plasmid 1) position: , mismatch: 8, identity: 0.784

tgcatgtcg-tggtcggcctgatggtgccgatcacgga	CRISPR spacer
-ccatgctgctggtcggcctgatggcgctgatcacgct	Protospacer
  ****..* ***************.**.*******

21. spacer 15.19|5279628|35|NC_019892|CRISPRCasFinder,CRT matches to NZ_CP035424 (Leisingera sp. NJS204 plasmid unnamed7, complete sequence) position: , mismatch: 8, identity: 0.771

cgagacctggccgtccagatcgaccggcgtgactt	CRISPR spacer
cgagccctggctgtccagatcgaccaccagcacct	Protospacer
**** ******.*************. *.  **.*

22. spacer 15.19|5279628|35|NC_019892|CRISPRCasFinder,CRT matches to NZ_CP038236 (Leisingera sp. NJS201 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.771

cgagacctggccgtccagatcgaccggcgtgactt	CRISPR spacer
cgagccctggctgtccagatcgaccaccagcacct	Protospacer
**** ******.*************. *.  **.*

23. spacer 15.19|5279628|35|NC_019892|CRISPRCasFinder,CRT matches to NZ_CP015043 (Rhodovulum sp. P5 plasmid pRGUI04, complete sequence) position: , mismatch: 8, identity: 0.771

cgagacctggccgtccagatcgaccggcgtgactt	CRISPR spacer
cgagccctggctgtccagatcgaccaccagcacct	Protospacer
**** ******.*************. *.  **.*

24. spacer 15.70|5279629|35|NC_019892|PILER-CR matches to NZ_CP035424 (Leisingera sp. NJS204 plasmid unnamed7, complete sequence) position: , mismatch: 8, identity: 0.771

cgagacctggccgtccagatcgaccggcgtgactt	CRISPR spacer
cgagccctggctgtccagatcgaccaccagcacct	Protospacer
**** ******.*************. *.  **.*

25. spacer 15.70|5279629|35|NC_019892|PILER-CR matches to NZ_CP038236 (Leisingera sp. NJS201 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.771

cgagacctggccgtccagatcgaccggcgtgactt	CRISPR spacer
cgagccctggctgtccagatcgaccaccagcacct	Protospacer
**** ******.*************. *.  **.*

26. spacer 15.70|5279629|35|NC_019892|PILER-CR matches to NZ_CP015043 (Rhodovulum sp. P5 plasmid pRGUI04, complete sequence) position: , mismatch: 8, identity: 0.771

cgagacctggccgtccagatcgaccggcgtgactt	CRISPR spacer
cgagccctggctgtccagatcgaccaccagcacct	Protospacer
**** ******.*************. *.  **.*

27. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP021025 (Rhizobium sp. TAL182 plasmid pRetTAL182a, complete sequence) position: , mismatch: 8, identity: 0.778

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
ctcccccgcgccgctctgcgccgaggagatcgccga	Protospacer
 **   * ****** * ******************

28. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP013600 (Rhizobium sp. N741 plasmid pRspN741e, complete sequence) position: , mismatch: 8, identity: 0.778

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
ctcccccgcgccgctctgcgccgaggagatcgccga	Protospacer
 **   * ****** * ******************

29. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP013504 (Rhizobium esperanzae strain N561 plasmid pRspN561d, complete sequence) position: , mismatch: 8, identity: 0.778

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
ctcccccgcgccgctctgcgccgaggagatcgccga	Protospacer
 **   * ****** * ******************

30. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP013510 (Rhizobium sp. N1341 plasmid pRspN1341e, complete sequence) position: , mismatch: 8, identity: 0.778

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
ctcccccgcgccgctctgcgccgaggagatcgccga	Protospacer
 **   * ****** * ******************

31. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP013521 (Rhizobium sp. N113 plasmid pRspN113d, complete sequence) position: , mismatch: 8, identity: 0.778

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
ctcccccgcgccgctctgcgccgaggagatcgccga	Protospacer
 **   * ****** * ******************

32. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP013494 (Rhizobium sp. N6212 plasmid pRspN6212d, complete sequence) position: , mismatch: 8, identity: 0.778

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
ctcccccgcgccgctctgcgccgaggagatcgccga	Protospacer
 **   * ****** * ******************

33. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP013512 (Rhizobium sp. N1314 plasmid pRspN1314a, complete sequence) position: , mismatch: 8, identity: 0.778

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
ctcccccgcgccgctctgcgccgaggagatcgccga	Protospacer
 **   * ****** * ******************

34. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP013594 (Rhizobium sp. N871 plasmid pRspN871d, complete sequence) position: , mismatch: 8, identity: 0.778

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
ctcccccgcgccgctctgcgccgaggagatcgccga	Protospacer
 **   * ****** * ******************

35. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to MF919536 (Mycobacterium phage TipsytheTRex, complete genome) position: , mismatch: 8, identity: 0.771

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gaccgggtgaacgccgacttcgacagccgttcgcc	Protospacer
**** ********************  * .* .*

36. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to MG099947 (Mycobacterium phage Ph8s, complete genome) position: , mismatch: 8, identity: 0.771

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gacttggtgaacgccgacttcgacagccggttgcc	Protospacer
***.*********************  *  * .*

37. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to MH020237 (Mycobacterium phage Jsquared, complete genome) position: , mismatch: 8, identity: 0.771

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gaccgggtgaacgccgacttcgacagccgttcgcc	Protospacer
**** ********************  * .* .*

38. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to MN585989 (Mycobacterium phage Superchunk, complete genome) position: , mismatch: 8, identity: 0.771

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gacttggtgaacgcggacttcgacaggcgcttgcc	Protospacer
***.********** ********** .* ** .*

39. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to KM197169 (Mycobacterium phage Piro94, complete genome) position: , mismatch: 8, identity: 0.771

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gacctggtgaacgctgccttcgacagccgctcccc	Protospacer
**************.* ********  * **  *

40. spacer 2.25|475890|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 9, identity: 0.743

cttcaatggcgaagtcctcgcccaggtcgatggcc	CRISPR spacer
cggggacgtagaagtcctcgcccatgtcgacggcc	Protospacer
*   .*.*  ************** *****.****

41. spacer 2.56|478115|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024308 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3a, complete sequence) position: , mismatch: 9, identity: 0.743

agcctggtgatcgtcaccggcccggggcagacggt	CRISPR spacer
cgcctggtgaccgtcaccggccccggaggaatggg	Protospacer
 *********.************ **. ..*.**

42. spacer 2.63|478623|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 9, identity: 0.735

acctccaccagaccgtcgcgatccgaaccgagat	CRISPR spacer
acctccaccagaccgtcgccatccatgtcgcagg	Protospacer
******************* ****. ..** ..

43. spacer 2.63|478623|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NC_015970 (Rhodothermus marinus SG0.5JP17-172 plasmid pRHOM17201, complete sequence) position: , mismatch: 9, identity: 0.735

acctccaccagaccgtcgcgatccgaaccgagat	CRISPR spacer
acctccaccagaccgtcgccatccatgtcgcagg	Protospacer
******************* ****. ..** ..

44. spacer 2.96|480999|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to MH617729 (Microviridae sp. isolate ctbh687, complete genome) position: , mismatch: 9, identity: 0.735

ccggagaac---gcgtgtgtggtcggaccggaatcgg	CRISPR spacer
---gaagtcgtagcgtgtgaggtcggaccagaatcgt	Protospacer
   **.. *   ******* *********.******

45. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019187 (Salmonella enterica subsp. enterica serovar Pomona str. ATCC 10729 plasmid pATCC10729_01, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

46. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024678 (Citrobacter freundii strain UMH16 plasmid pUMH16, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

47. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030220 (Salmonella enterica strain SA20021456 plasmid pSA20021456.1, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgagag	Protospacer
 ***************..********. .* . **

48. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024682 (Citrobacter freundii strain UMH14 plasmid pUMH14_2, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

49. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024674 (Citrobacter freundii strain UMH19 plasmid pUMH19, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

50. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011595 (Klebsiella oxytoca strain CAV1099 plasmid pKPC_CAV1099, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

51. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to CP053329 (Salmonella enterica subsp. salamae serovar 60:z10:z39 strain 2011K-1889 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgagag	Protospacer
 ***************..********. .* . **

52. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047309 (Citrobacter freundii strain L75 plasmid pCf76, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

53. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NC_019093 (Escherichia coli plasmid pLST424C-61, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

54. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030210 (Salmonella enterica strain SA20044414 plasmid pSA20044414.1, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

55. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026394 (Klebsiella pneumoniae strain KPNIH48 plasmid pKPC-e937, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

56. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP046347 (Citrobacter portucalensis strain FDAARGOS_738 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

57. spacer 2.102|481435|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044100 (Citrobacter werkmanii strain FDAARGOS_616 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

ggtatcgtcgcgggcctcgatatccttgttcgtag	CRISPR spacer
cgtatcgtcgcgggccctgatatcctccctgacag	Protospacer
 ***************..********. .* ..**

58. spacer 2.141|484235|37|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NC_018580 (Gordonia sp. KTR9 plasmid pGKT2, complete sequence) position: , mismatch: 9, identity: 0.757

tgcatg-tcgtggtcggcctgatggtgccgatcacgga	CRISPR spacer
-gtgtgatcgtggtcggcctggtggtggcgatcgtcgt	Protospacer
 *..** **************.***** *****.. *

59. spacer 2.149|484806|33|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025114 (Bradyrhizobium sp. SK17 strain CBNU plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

atcgcggaacgcaccgtcgtgatcgaccggacc	CRISPR spacer
ctcgcggacggcaccgtcgtgatcgcgaagaag	Protospacer
 *******  ***************   .**

60. spacer 2.149|484806|33|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025114 (Bradyrhizobium sp. SK17 strain CBNU plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.727

atcgcggaacgcaccgtcgtgatcgaccggacc	CRISPR spacer
ctcgcggacggcaccgtcgtgatcgcgaagaag	Protospacer
 *******  ***************   .**

61. spacer 2.149|484806|33|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043960 (Streptomyces tendae strain 139 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.727

atcgcggaacgcaccgtcgtgatcgaccggacc	CRISPR spacer
gcctcggaacgcaccgtcctgaacgacctggtt	Protospacer
..* ************** *** ***** *...

62. spacer 2.153|485091|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024423 (Paracoccus yeei strain TT13 plasmid pTT13-1, complete sequence) position: , mismatch: 9, identity: 0.735

acggtcgagttcgacgccaagggggctctggctg	CRISPR spacer
aaggccgagttcgacgccaagggcgcgaagaagg	Protospacer
* **.****************** **   *.  *

63. spacer 2.153|485091|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020441 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

acggtcgagttcgacgccaagggggctctggctg	CRISPR spacer
aaggccgagttcgacgccaagggcgcgaagaagg	Protospacer
* **.****************** **   *.  *

64. spacer 2.153|485091|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044080 (Paracoccus yeei strain FDAARGOS_643 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.735

acggtcgagttcgacgccaagggggctctggctg	CRISPR spacer
aaggccgagttcgacgccaagggcgcgaagaagg	Protospacer
* **.****************** **   *.  *

65. spacer 2.153|485091|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031079 (Paracoccus yeei strain CCUG 32053 plasmid pYEE1, complete sequence) position: , mismatch: 9, identity: 0.735

acggtcgagttcgacgccaagggggctctggctg	CRISPR spacer
aaggccgagttcgacgccaagggcgcgaagaagg	Protospacer
* **.****************** **   *.  *

66. spacer 2.154|485161|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 9, identity: 0.743

ggcgatcgcaaagccgatgtcccgctgccaggccg	CRISPR spacer
atggatcgcaaagccgatgtcatgctgcatgccgg	Protospacer
.  ****************** .*****  * * *

67. spacer 2.154|485161|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 9, identity: 0.743

ggcgatcgcaaagccgatgtcccgctgccaggccg	CRISPR spacer
atggatcgcaaagccgatgtcatgctgcatgccgg	Protospacer
.  ****************** .*****  * * *

68. spacer 14.2|5269513|32|NC_019892|CRT matches to NC_048053 (Dickeya phage vB_DsoM_JA29, complete genome) position: , mismatch: 9, identity: 0.719

aggtattgcgagccgtgctttcacactgacgc	CRISPR spacer
gataagtgcgagccgtgttatcacactgatga	Protospacer
..  * ***********.* *********.*

69. spacer 15.3|5278458|36|NC_019892|CRISPRCasFinder,CRT matches to NC_010865 (Sinorhizobium meliloti plasmid pSmeSM11b, complete sequence) position: , mismatch: 9, identity: 0.75

ggtgggcatcgacaccaacgatcccgacttgcacaa	CRISPR spacer
acaatgcatcgaagccaacgatcccgacttgcaaag	Protospacer
.  . ******* .******************* *.

70. spacer 15.3|5278458|36|NC_019892|CRISPRCasFinder,CRT matches to NZ_CP021216 (Sinorhizobium meliloti RU11/001 plasmid pSmeRU11d, complete sequence) position: , mismatch: 9, identity: 0.75

ggtgggcatcgacaccaacgatcccgacttgcacaa	CRISPR spacer
acaatgcatcgaagccaacgatcccgacttgcaaag	Protospacer
.  . ******* .******************* *.

71. spacer 15.19|5279628|35|NC_019892|CRISPRCasFinder,CRT matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 9, identity: 0.743

cgagacctggccgtccagatcgaccggcgtgactt	CRISPR spacer
caggacctggccgtccagatcgaagggccggccca	Protospacer
*..********************  ***  * *.

72. spacer 15.47|5281676|35|NC_019892|CRISPRCasFinder,CRT matches to NZ_CP018468 (Xanthomonas vesicatoria strain LM159 plasmid pLM159.1, complete sequence) position: , mismatch: 9, identity: 0.743

cgaccaggccgatgccaacccggagctcaactgat	CRISPR spacer
cgaccaggccgatgccaaccgcgagacctgccgca	Protospacer
********************  *** .* .*.*

73. spacer 15.54|5278459|36|NC_019892|PILER-CR matches to NC_010865 (Sinorhizobium meliloti plasmid pSmeSM11b, complete sequence) position: , mismatch: 9, identity: 0.75

ggtgggcatcgacaccaacgatcccgacttgcacaa	CRISPR spacer
acaatgcatcgaagccaacgatcccgacttgcaaag	Protospacer
.  . ******* .******************* *.

74. spacer 15.54|5278459|36|NC_019892|PILER-CR matches to NZ_CP021216 (Sinorhizobium meliloti RU11/001 plasmid pSmeRU11d, complete sequence) position: , mismatch: 9, identity: 0.75

ggtgggcatcgacaccaacgatcccgacttgcacaa	CRISPR spacer
acaatgcatcgaagccaacgatcccgacttgcaaag	Protospacer
.  . ******* .******************* *.

75. spacer 15.70|5279629|35|NC_019892|PILER-CR matches to NZ_CP035710 (Sphaerotilus natans subsp. sulfidivorans strain D-507 plasmid pSna507_unt10, complete sequence) position: , mismatch: 9, identity: 0.743

cgagacctggccgtccagatcgaccggcgtgactt	CRISPR spacer
caggacctggccgtccagatcgaagggccggccca	Protospacer
*..********************  ***  * *.

76. spacer 15.98|5281677|35|NC_019892|PILER-CR matches to NZ_CP018468 (Xanthomonas vesicatoria strain LM159 plasmid pLM159.1, complete sequence) position: , mismatch: 9, identity: 0.743

cgaccaggccgatgccaacccggagctcaactgat	CRISPR spacer
cgaccaggccgatgccaaccgcgagacctgccgca	Protospacer
********************  *** .* .*.*

77. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgcgggc	Protospacer
***** **************.****** .*    *.

78. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgcgggc	Protospacer
***** **************.****** .*    *.

79. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgcgggc	Protospacer
***** **************.****** .*    *.

80. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgctggc	Protospacer
***** **************.****** .*  . *.

81. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgctggc	Protospacer
***** **************.****** .*  . *.

82. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgcgggc	Protospacer
***** **************.****** .*    *.

83. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgcgggc	Protospacer
***** **************.****** .*    *.

84. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgcgggc	Protospacer
***** **************.****** .*    *.

85. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgcgggc	Protospacer
***** **************.****** .*    *.

86. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgcgggc	Protospacer
***** **************.****** .*    *.

87. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgtgcgggc	Protospacer
***** **************.****** .*    *.

88. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NC_008243 (Chelativorans sp. BNC1 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.75

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gcccgccacggcgcacagcgccgaggagatcgccac	Protospacer
*.* . * ** ***.*******************..

89. spacer 16.17|5292702|35|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP049749 (Rhodococcus fascians A21d2 plasmid pA21d2, complete sequence) position: , mismatch: 9, identity: 0.743

ttcgagaagacgatcgaatgctacgtcaacggcga	CRISPR spacer
tcaggcgagacgatcgaattctccgtcaacggtgt	Protospacer
*. *. .************ ** *********.*

90. spacer 16.31|5293727|35|NC_019892|CRT,CRISPRCasFinder matches to NC_008759 (Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence) position: , mismatch: 9, identity: 0.743

ctgccgtccgtggtcgtcgacgccggccagttcgg	CRISPR spacer
gtgccgttcgtggtcggcgacgccggtccgcgcat	Protospacer
 ******.******** *********.* *. *.

91. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_MF150120 (Klebsiella pneumoniae strain A64477 plasmid pKP64477d, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

92. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_KX756453 (Klebsiella pneumoniae strain 1194/11 plasmid pKP1194a, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

93. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP014069 (Citrobacter amalonaticus strain FDAARGOS_165 plasmid unnamed) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

94. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP003997 (Klebsiella pneumoniae subsp. pneumoniae Kp13 plasmid pKP13d, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

95. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP032305 (Salmonella enterica subsp. enterica serovar Braenderup strain FORC93 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

96. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP043513 (Enterobacter kobei strain EB_P8_L5_01.19 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

97. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP027700 (Klebsiella pneumoniae strain KP30835 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

98. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_MK264770 (Klebsiella pneumoniae strain KP89 plasmid pKP89, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

99. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_KU963389 (Escherichia coli strain ECO37 plasmid ECO37P1, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

100. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP026758 (Klebsiella aerogenes strain AR_0062 plasmid tig00000058_pilon, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

101. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to KR822247 (Escherichia coli strain E0083033-2 plasmid pEc2A, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggtaatcagtgccagaaccggctttccccagggc	Protospacer
  **  * .**** ***.*****************.

102. spacer 16.72|5296755|36|NC_019892|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP030195 (Salmonella enterica strain SA20080453 plasmid pSA20080453.1, complete sequence) position: , mismatch: 9, identity: 0.75

cgggacagtagtggcaggaccggctttccccagggt	CRISPR spacer
acggttatcagtgtcagaaccggctttccccagggg	Protospacer
  ** .* .**** ***.*****************

103. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to NC_025025 (Mycobacterium tuberculosis H37Rv plasmid pTYGi9, complete sequence) position: , mismatch: 9, identity: 0.743

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gacttggtgaacgcggacttcgacagccggttgcc	Protospacer
***.********** **********  *  * .*

104. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to M65194 (Mycobacterium phage L5 integrase (int) gene, complete cds) position: , mismatch: 9, identity: 0.743

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gacttggtgaacgcggacttcgacagccggttgcc	Protospacer
***.********** **********  *  * .*

105. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to NC_008203 (Mycobacterium phage Che12, complete genome) position: , mismatch: 9, identity: 0.743

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gacttggtgaacgcggacttcgacagccggttgcc	Protospacer
***.********** **********  *  * .*

106. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to NC_022058 (Mycobacterium phage Adzzy, complete genome) position: , mismatch: 9, identity: 0.743

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gacttggtgaacgcggacttcgacagccggttgcc	Protospacer
***.********** **********  *  * .*

107. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to KX683423 (Mycobacterium phage BabyRay, complete genome) position: , mismatch: 9, identity: 0.743

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gaccgggtgaaggccgacttcgacagccggttccc	Protospacer
**** ****** *************  *  *  *

108. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to DQ398043 (Mycobacterium virus Che12, complete genome) position: , mismatch: 9, identity: 0.743

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gacttggtgaacgcggacttcgacagccggttgcc	Protospacer
***.********** **********  *  * .*

109. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to KT381276 (Mycobacterium phage Serenity, complete genome) position: , mismatch: 9, identity: 0.743

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gagcgggtgaacgccgacttcgacagccgttcgcc	Protospacer
** * ********************  * .* .*

110. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to Z18946 (Mycobacterium phage L5 complete genome) position: , mismatch: 9, identity: 0.743

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gacttggtgaacgcggacttcgacagccggttgcc	Protospacer
***.********** **********  *  * .*

111. spacer 17.34|5320516|35|NC_019892|CRISPRCasFinder,CRT matches to NC_017973 (Mycobacterium phage SWU1, complete genome) position: , mismatch: 9, identity: 0.743

gacctggtgaacgccgacttcgacacaccctgacg	CRISPR spacer
gacttggtgaacgcggacttcgacagccggttgcc	Protospacer
***.********** **********  *  * .*

112. spacer 2.14|475100|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021372 (Rhizobium sp. ACO-34A plasmid pRACO34Ad, complete sequence) position: , mismatch: 10, identity: 0.706

ttatcaccatcgcctggcttcagggtcgcatgca	CRISPR spacer
ccttcaccatcgcctggcttcttggtctggaaca	Protospacer
.. ******************  ****  . .**

113. spacer 2.20|475533|36|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to MN908687 (Gordonia phage Skog, complete genome) position: , mismatch: 10, identity: 0.722

ctccatagtggcggcgggtttggcgagcagcacagc	CRISPR spacer
atgcgcggtgtcggcgggtttggccagcagcacgag	Protospacer
 * *...*** ************* ********..

114. spacer 2.121|482793|37|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032695 (Rhizobium jaguaris strain CCGE525 plasmid pRCCGE525c, complete sequence) position: , mismatch: 10, identity: 0.73

-aatacgtgccgacgatcccgatgaaggcccgcccggt	CRISPR spacer
ttgtat-cgccggcgatcccgatgaaggcgcgcctgac	Protospacer
  .**. .****.**************** ****.*..

115. spacer 2.144|484451|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017105 (Rhizobium gallicum strain IE4872 plasmid pRgalIE4872d, complete sequence) position: , mismatch: 10, identity: 0.706

aaaccgaaggcccctcgatcgtcttgcctcgctt	CRISPR spacer
cgcccgaaggccgctcgatcgtcgtgcttgccaa	Protospacer
 . ********* ********** ***.*  *

116. spacer 13.1|5262311|35|NC_019892|CRISPRCasFinder matches to CP011075 (Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

ccgtggctgaggatcgctcatatattgaatcattt	CRISPR spacer
ttctggctgaggatcgccaatatattgaagtaaca	Protospacer
.. **************. ********** .* .

117. spacer 13.1|5262311|35|NC_019892|CRISPRCasFinder matches to NZ_CP011154 (Bacillus cereus strain CMCC P0011 plasmid pRML05, complete sequence) position: , mismatch: 10, identity: 0.714

ccgtggctgaggatcgctcatatattgaatcattt	CRISPR spacer
ttctggctgaggatcgccaatatattgaagtaaca	Protospacer
.. **************. ********** .* .

118. spacer 13.1|5262311|35|NC_019892|CRISPRCasFinder matches to NZ_CP011152 (Bacillus cereus strain CMCC P0021 plasmid pRML04, complete sequence) position: , mismatch: 10, identity: 0.714

ccgtggctgaggatcgctcatatattgaatcattt	CRISPR spacer
ttctggctgaggatcgccaatatattgaagtaaca	Protospacer
.. **************. ********** .* .

119. spacer 13.1|5262311|35|NC_019892|CRISPRCasFinder matches to CP020755 (Bacillus thuringiensis strain ATCC 10792 plasmid pLDW-16, complete sequence) position: , mismatch: 10, identity: 0.714

ccgtggctgaggatcgctcatatattgaatcattt	CRISPR spacer
ttctggctgaggatcgccaatatattgaagtaaca	Protospacer
.. **************. ********** .* .

120. spacer 13.1|5262311|35|NC_019892|CRISPRCasFinder matches to NC_020385 (Bacillus thuringiensis serovar thuringiensis str. IS5056 plasmid pIS56-328, complete sequence) position: , mismatch: 10, identity: 0.714

ccgtggctgaggatcgctcatatattgaatcattt	CRISPR spacer
ttctggctgaggatcgccaatatattgaagtaaca	Protospacer
.. **************. ********** .* .

121. spacer 13.1|5262311|35|NC_019892|CRISPRCasFinder matches to NZ_CP021062 (Bacillus thuringiensis strain ATCC 10792 plasmid poh1, complete sequence) position: , mismatch: 10, identity: 0.714

ccgtggctgaggatcgctcatatattgaatcattt	CRISPR spacer
ttctggctgaggatcgccaatatattgaagtaaca	Protospacer
.. **************. ********** .* .

122. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 10, identity: 0.722

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
gtcgatctcgccgcgcagcgtcgaggatgcgctggc	Protospacer
***** **************.****** ..  . *.

123. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to CP000663 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA02, complete sequence) position: , mismatch: 10, identity: 0.722

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
ccacggcgcgccgctcggcgccgaggagatcgccgc	Protospacer
 .  ..* ****** *.******************.

124. spacer 16.15|5292558|36|NC_019892|CRT,CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.722

gtcgaactcgccgcgcagcgccgaggagatcgccgt	CRISPR spacer
atcgatctcgccgcgcagcgtcgaggatgtgcgggc	Protospacer
.**** **************.****** .*    *.

125. spacer 17.22|5319638|37|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032685 (Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence) position: , mismatch: 10, identity: 0.73

gcacgttgccggtgatgatgaggccggagtaagcgcc	CRISPR spacer
gcacgctgccgatgatgatgaggccgagccagcccgc	Protospacer
*****.*****.**************.. .*. *  *

126. spacer 17.22|5319638|37|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032690 (Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence) position: , mismatch: 10, identity: 0.73

gcacgttgccggtgatgatgaggccggagtaagcgcc	CRISPR spacer
gcacgctgccgatgatgatgaggccgagccagcccgc	Protospacer
*****.*****.**************.. .*. *  *

127. spacer 2.69|479047|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to LC494302 (Escherichia phage SP27 DNA, complete genome) position: , mismatch: 11, identity: 0.676

aaacgccatccgtgatgggataaagcgcaacgac	CRISPR spacer
ttacgccatccatcatgggataaagcatttgatc	Protospacer
  *********.* ************..   . *

128. spacer 2.69|479047|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to MH791411 (UNVERIFIED: Escherichia phage Ecwhy_1, complete genome) position: , mismatch: 11, identity: 0.676

aaacgccatccgtgatgggataaagcgcaacgac	CRISPR spacer
ttacgccatccattatgggataaagcatttgatc	Protospacer
  *********.* ************..   . *

129. spacer 2.69|479047|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NC_027364 (Escherichia phage PBECO 4, complete genome) position: , mismatch: 11, identity: 0.676

aaacgccatccgtgatgggataaagcgcaacgac	CRISPR spacer
ttacgccatccatcatgggataaagcatttgatc	Protospacer
  *********.* ************..   . *

130. spacer 2.69|479047|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to MH383160 (Escherichia phage UB, complete genome) position: , mismatch: 11, identity: 0.676

aaacgccatccgtgatgggataaagcgcaacgac	CRISPR spacer
ttacgccatccatcatgggataaagcatttgatc	Protospacer
  *********.* ************..   . *

131. spacer 2.69|479047|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to MK327931 (Escherichia phage vB_EcoM_G17, complete genome) position: , mismatch: 11, identity: 0.676

aaacgccatccgtgatgggataaagcgcaacgac	CRISPR spacer
ttacgccatccatcatgggataaagcatttgatc	Protospacer
  *********.* ************..   . *

132. spacer 2.69|479047|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to MK327931 (Escherichia phage vB_EcoM_G17, complete genome) position: , mismatch: 11, identity: 0.676

aaacgccatccgtgatgggataaagcgcaacgac	CRISPR spacer
ttacgccatccatcatgggataaagcatttgatc	Protospacer
  *********.* ************..   . *

133. spacer 2.69|479047|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to MH494197 (Escherichia phage CMSTMSU, complete genome) position: , mismatch: 11, identity: 0.676

aaacgccatccgtgatgggataaagcgcaacgac	CRISPR spacer
ttacgccatccatcatgggataaagcatttgatc	Protospacer
  *********.* ************..   . *

134. spacer 2.69|479047|34|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to LT603033 (Escherichia phage vB_Eco_slurp01 genome assembly, chromosome: I) position: , mismatch: 11, identity: 0.676

aaacgccatccgtgatgggataaagcgcaacgac	CRISPR spacer
ttacgccatccatcatgggataaagcatttgatc	Protospacer
  *********.* ************..   . *

135. spacer 2.132|483589|38|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to HM486077 (Tsukamurella phage TPA2, complete sequence) position: , mismatch: 11, identity: 0.711

gcgctccggcacaagatcgggctcgtgatcctcgacta	CRISPR spacer
gtcgccgagcacaagatcgggctggtgatcttcgatac	Protospacer
*.  .* .*************** ******.****.

136. spacer 2.132|483589|38|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NC_015210 (Tsukamurella phage TPA2, complete genome) position: , mismatch: 11, identity: 0.711

gcgctccggcacaagatcgggctcgtgatcctcgacta	CRISPR spacer
gtcgccgagcacaagatcgggctggtgatcttcgatac	Protospacer
*.  .* .*************** ******.****.

137. spacer 17.22|5319638|37|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NC_015057 (Granulicella tundricola MP5ACTX9 plasmid pACIX901, complete sequence) position: , mismatch: 11, identity: 0.703

gcacgttgccggtgatgatgaggccggagtaagcgcc	CRISPR spacer
cattgttgccggcgatgatgatgccggagttggagat	Protospacer
   .********.******** ******** .* * .

138. spacer 17.59|5322331|35|NC_019892|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP026539 (Desulfovibrio carbinolicus strain DSM 3852 plasmid pDCAR1, complete sequence) position: , mismatch: 11, identity: 0.686

atgtcgccgccagcaagccgcagccgctcattctc	CRISPR spacer
acgtcgccgccagcaacccgccgccgccggccagg	Protospacer
*.************** **** *****. ...

139. spacer 17.28|5320078|35|NC_019892|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP038637 (Cupriavidus oxalaticus strain X32 plasmid unnamed2, complete sequence) position: , mismatch: 12, identity: 0.657

tgccttgacttgggccttcacggaagactggatga	CRISPR spacer
ggccttgactagtgccttcacggaagcggaagctg	Protospacer
 ********* * *************   .... .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

354918 : 441335

Bacillus_phage(16.67%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015243913.1\|354918_356262_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_015243914.1\|356798_358298_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_015243916.1\|358987_360013_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_020465471.1\|360275_361856_-	response regulator	W8CYF6	Bacillus_phage	4.4e-16	25.3
WP_015243918.1\|361861_362443_-	chemotaxis protein CheB	NA	NA	NA	NA
WP_015243919.1\|362439_363267_-	chemotaxis protein CheR	NA	NA	NA	NA
WP_015243920.1\|363281_366755_-	response regulator	A0A1V0SGX0	Hokovirus	2.4e-35	39.1
WP_020465473.1\|367384_367576_+	hypothetical protein	NA	NA	NA	NA
WP_015243922.1\|367802_368612_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_052334737.1\|369374_375749_-	RHS repeat-associated core domain-containing protein	NA	NA	NA	NA
WP_015243926.1\|378696_378888_+	hypothetical protein	NA	NA	NA	NA
WP_020465477.1\|379067_379211_+	hypothetical protein	NA	NA	NA	NA
WP_015243927.1\|379266_379710_-	hypothetical protein	NA	NA	NA	NA
WP_015243928.1\|380044_380506_+	glucosaminidase domain-containing protein	NA	NA	NA	NA
WP_154673590.1\|380844_381141_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_015243929.1\|381178_381766_-	hypothetical protein	NA	NA	NA	NA
WP_015243930.1\|382083_382812_-	DUF1573 domain-containing protein	NA	NA	NA	NA
WP_015243931.1\|382853_383999_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_015243932.1\|384112_385399_-	hypothetical protein	NA	NA	NA	NA
WP_081578419.1\|386388_387390_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_015243936.1\|388934_389435_+	chemotaxis protein CheW	NA	NA	NA	NA
WP_015243937.1\|389460_391908_+	GAF domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	5.0e-11	30.9
WP_020467711.1\|391929_392769_+	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_015243939.1\|392794_395119_+	chemotaxis protein CheA	NA	NA	NA	NA
WP_015243940.1\|395177_395810_+	chemotaxis protein CheC, inhibitor of MCP methylation	NA	NA	NA	NA
WP_015243941.1\|395884_396340_+	chemotaxis protein CheD	NA	NA	NA	NA
WP_015243942.1\|396394_396835_+	response regulator	NA	NA	NA	NA
WP_044147380.1\|396878_397922_+	chemotaxis response regulator protein-glutamate methylesterase	NA	NA	NA	NA
WP_015243944.1\|400364_400784_-	hypothetical protein	NA	NA	NA	NA
WP_015243945.1\|400831_401785_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_081578421.1\|402355_402598_+\|transposase	transposase	NA	NA	NA	NA
WP_015243947.1\|403517_403790_-	hypothetical protein	NA	NA	NA	NA
WP_015243948.1\|404389_405250_-	hypothetical protein	NA	NA	NA	NA
WP_015243949.1\|405518_406229_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_015243950.1\|406281_407589_-	carbonic anhydrase	NA	NA	NA	NA
WP_157579489.1\|407982_409041_-	glycosyltransferase	NA	NA	NA	NA
WP_015243952.1\|409349_410495_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_020467721.1\|410511_411021_-	hypoxanthine phosphoribosyltransferase	A0A2K9L634	Tupanvirus	3.1e-16	30.0
WP_015243954.1\|411263_413603_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015243955.1\|414076_414727_-	hypothetical protein	NA	NA	NA	NA
WP_015243956.1\|415300_415891_+	RNA polymerase sigma factor	NA	NA	NA	NA
WP_015243957.1\|415973_416552_+	hypothetical protein	NA	NA	NA	NA
WP_015243958.1\|416548_417034_+	hypothetical protein	NA	NA	NA	NA
WP_015243959.1\|417483_418608_+	tagatose 1,6-diphosphate aldolase	NA	NA	NA	NA
WP_020467723.1\|418971_422736_-	hypothetical protein	NA	NA	NA	NA
WP_015243961.1\|422800_423340_-	HAD family hydrolase	A0A140XBD6	Dickeya_phage	7.9e-18	41.0
WP_015243962.1\|423345_424368_-	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	8.2e-32	31.9
WP_015243963.1\|425273_428048_+	hypothetical protein	NA	NA	NA	NA
WP_015243964.1\|428291_429068_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015243965.1\|429974_437120_+	RHS repeat-associated core domain-containing protein	NA	NA	NA	NA
WP_015243966.1\|437116_437557_+	hypothetical protein	NA	NA	NA	NA
WP_015243967.1\|437617_439111_+	RHS repeat-associated core domain-containing protein	NA	NA	NA	NA
WP_015243968.1\|439134_440178_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_015243969.1\|440915_441335_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_2

664219 : 716796

Morganella_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015244133.1\|664219_665560_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_015244134.1\|666067_668272_+	recombinase family protein	NA	NA	NA	NA
WP_020467654.1\|668405_668498_+	hypothetical protein	NA	NA	NA	NA
WP_015244135.1\|668546_669590_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_015244136.1\|669703_670132_+	TIGR03067 domain-containing protein	NA	NA	NA	NA
WP_015244137.1\|670299_670728_+	TIGR03067 domain-containing protein	NA	NA	NA	NA
WP_157579403.1\|670764_670959_+\|transposase	transposase	NA	NA	NA	NA
WP_020467417.1\|671243_671726_-	hypothetical protein	NA	NA	NA	NA
WP_020467416.1\|671778_671901_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015244139.1\|672147_672375_+	hypothetical protein	NA	NA	NA	NA
WP_015244140.1\|672634_673183_+	dihydrofolate reductase family protein	NA	NA	NA	NA
WP_015244141.1\|673392_674544_+	hypothetical protein	NA	NA	NA	NA
WP_015244142.1\|675864_676182_+	hypothetical protein	NA	NA	NA	NA
WP_015244143.1\|676364_677174_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_015244146.1\|678176_678614_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_174377927.1\|679142_679472_+	hypothetical protein	NA	NA	NA	NA
WP_015244149.1\|679694_680258_+	SIS domain-containing protein	NA	NA	NA	NA
WP_015244150.1\|680254_681088_+	HAD family hydrolase	NA	NA	NA	NA
WP_015244151.1\|681084_682194_+	hypothetical protein	NA	NA	NA	NA
WP_015244152.1\|682190_683216_+	carbohydrate kinase	NA	NA	NA	NA
WP_015244153.1\|683445_684192_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_015244154.1\|684278_684749_-	hypothetical protein	NA	NA	NA	NA
WP_015244155.1\|684821_686033_+	nucleotidyltransferase	A0A1W6JNT0	Morganella_phage	2.9e-36	32.0
WP_015244156.1\|686109_687087_-	DUF72 domain-containing protein	NA	NA	NA	NA
WP_015244157.1\|688085_688718_+	DUF2239 family protein	NA	NA	NA	NA
WP_015244158.1\|689163_689523_+	RNA-binding protein	NA	NA	NA	NA
WP_015244159.1\|689927_690551_+	hypothetical protein	NA	NA	NA	NA
WP_154673907.1\|690780_691275_+	hypothetical protein	NA	NA	NA	NA
WP_015244161.1\|691666_693052_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_015244162.1\|693360_694323_-	pseudouridine-5'-phosphate glycosidase	NA	NA	NA	NA
WP_020467408.1\|694510_695842_+	protein kinase	M1PWP3	Moumouvirus	2.7e-11	26.2
WP_015244164.1\|695941_697366_-	sulfatase	NA	NA	NA	NA
WP_015244165.1\|697579_698533_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_015244166.1\|698532_699015_+	hypothetical protein	NA	NA	NA	NA
WP_015244168.1\|699261_699741_-	hypothetical protein	NA	NA	NA	NA
WP_015244169.1\|699807_700767_-	diacylglycerol kinase family lipid kinase	NA	NA	NA	NA
WP_015244170.1\|700785_701415_-	SCO family protein	NA	NA	NA	NA
WP_015244171.1\|701450_702650_-	selenium-binding protein	NA	NA	NA	NA
WP_015244172.1\|702708_703149_-	DUF2784 domain-containing protein	NA	NA	NA	NA
WP_015244173.1\|703605_705555_+	UDP-N-acetylmuramyl tripeptide synthase	NA	NA	NA	NA
WP_015244174.1\|705753_706056_+	hypothetical protein	NA	NA	NA	NA
WP_015244175.1\|706298_707492_-	galactokinase	NA	NA	NA	NA
WP_015244176.1\|707587_708769_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.0e-126	57.7
WP_015244177.1\|709083_710130_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_020467403.1\|710354_710549_-	hypothetical protein	NA	NA	NA	NA
WP_015244179.1\|711216_712056_-	hypothetical protein	NA	NA	NA	NA
WP_015244180.1\|712151_714968_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015244181.1\|715410_716796_-\|transposase	IS4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1512215 : 1592448

Klosneuvirus(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015244770.1\|1512215_1513202_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_020465827.1\|1513299_1513509_+	hypothetical protein	NA	NA	NA	NA
WP_052315630.1\|1513713_1514319_-	hypothetical protein	NA	NA	NA	NA
WP_015244773.1\|1514605_1516030_-\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_052315629.1\|1516013_1516967_-	hypothetical protein	NA	NA	NA	NA
WP_015244774.1\|1517231_1517945_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_015244775.1\|1518189_1521138_+	DUF1553 domain-containing protein	NA	NA	NA	NA
WP_015244776.1\|1521187_1522621_+	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_015244777.1\|1522660_1523578_-	hypothetical protein	NA	NA	NA	NA
WP_015244778.1\|1523574_1524156_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_015244779.1\|1524191_1524500_-	hypothetical protein	NA	NA	NA	NA
WP_015244780.1\|1524653_1525259_-	kinase aspartokinase/uridylate kinase	NA	NA	NA	NA
WP_015244781.1\|1525255_1526314_-	H4MPT-linked C1 transfer pathway protein	NA	NA	NA	NA
WP_015244782.1\|1526306_1527365_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_015244783.1\|1527389_1528217_+	hisA/hisF family protein	NA	NA	NA	NA
WP_015244784.1\|1528247_1529234_-\|transposase	transposase	NA	NA	NA	NA
WP_015244785.1\|1529318_1529588_+	hypothetical protein	NA	NA	NA	NA
WP_015244786.1\|1529930_1530461_+	hypothetical protein	NA	NA	NA	NA
WP_015244787.1\|1530666_1531323_+	hypothetical protein	NA	NA	NA	NA
WP_015244788.1\|1531356_1532649_-	glycosyltransferase family 1 protein	A0A1V0SKQ0	Klosneuvirus	3.0e-15	45.5
WP_015244789.1\|1532679_1533504_-	hypothetical protein	NA	NA	NA	NA
WP_020465825.1\|1533540_1534284_-	hypothetical protein	NA	NA	NA	NA
WP_015244791.1\|1534637_1541483_+	glycosyltransferase	NA	NA	NA	NA
WP_020465823.1\|1541685_1542309_+	hypothetical protein	NA	NA	NA	NA
WP_015244793.1\|1542612_1542987_+	iron-sulfur cluster assembly scaffold protein	NA	NA	NA	NA
WP_015244795.1\|1543438_1544908_+\|transposase	transposase	NA	NA	NA	NA
WP_015244796.1\|1545058_1546588_-\|transposase	ISKra4 family transposase	NA	NA	NA	NA
WP_020465821.1\|1546565_1546901_+	hypothetical protein	NA	NA	NA	NA
WP_015244798.1\|1547556_1548048_-	6-carboxytetrahydropterin synthase	NA	NA	NA	NA
WP_015244799.1\|1548091_1548982_-	triphosphoribosyl-dephospho-CoA synthase	NA	NA	NA	NA
WP_157579497.1\|1548978_1549857_-	RimK family alpha-L-glutamate ligase	NA	NA	NA	NA
WP_015244801.1\|1549886_1550831_-	methenyltetrahydromethanopterin cyclohydrolase	NA	NA	NA	NA
WP_015244802.1\|1550860_1551691_-	formylmethanofuran dehydrogenase subunit C	NA	NA	NA	NA
WP_015244803.1\|1551873_1552830_-	SPFH domain-containing protein	NA	NA	NA	NA
WP_015244804.1\|1552927_1553827_-	formylmethanofuran--tetrahydromethanopterin N-formyltransferase	NA	NA	NA	NA
WP_015244805.1\|1553823_1555461_-	formylmethanofuran dehydrogenase subunit A	NA	NA	NA	NA
WP_015244806.1\|1555538_1556876_-	formylmethanofuran dehydrogenase subunit B	NA	NA	NA	NA
WP_015244807.1\|1557113_1557887_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	9.6e-09	26.4
WP_157579416.1\|1557894_1559343_+	dihydropteroate synthase	NA	NA	NA	NA
WP_015244809.1\|1559339_1559933_+	DUF447 family protein	NA	NA	NA	NA
WP_015244810.1\|1559929_1560889_+	beta-RFAP synthase	NA	NA	NA	NA
WP_015244811.1\|1561006_1562035_-	hypothetical protein	NA	NA	NA	NA
WP_015244812.1\|1562550_1562733_+	Flp family type IVb pilin	NA	NA	NA	NA
WP_015244814.1\|1563485_1572410_+	glycosyl transferase family 36	NA	NA	NA	NA
WP_015244816.1\|1573554_1575618_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.1e-27	23.5
WP_015244817.1\|1575649_1577062_-	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_015244818.1\|1577123_1577537_-	YjbQ family protein	NA	NA	NA	NA
WP_015244819.1\|1577515_1579828_-	protein kinase	A0A140IPJ4	Avian_leukosis_and_sarcoma_virus	3.2e-07	29.1
WP_015244820.1\|1580196_1581327_+	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_015244821.1\|1581622_1582486_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_015244822.1\|1582482_1583592_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_015244823.1\|1583588_1584656_-	alkene reductase	NA	NA	NA	NA
WP_015244825.1\|1584884_1586684_-	SufS family cysteine desulfurase	Q2XUY6	environmental_halophage	3.1e-95	41.8
WP_015244826.1\|1586680_1587694_-	carbon-nitrogen hydrolase family protein	M1I5T1	Acanthocystis_turfacea_Chlorella_virus	9.0e-07	25.8
WP_015244827.1\|1587902_1588046_-	hypothetical protein	NA	NA	NA	NA
WP_015244828.1\|1588144_1588519_-	DUF983 domain-containing protein	NA	NA	NA	NA
WP_015244829.1\|1588592_1589090_-	cupin domain-containing protein	NA	NA	NA	NA
WP_015244830.1\|1589358_1590990_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_086018129.1\|1591057_1592448_-\|transposase	ISKra4-like element ISSiac4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

2624228 : 2674941

Synechococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015245510.1\|2624228_2625683_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_081578279.1\|2625675_2626389_+	prolyl oligopeptidase family serine peptidase	NA	NA	NA	NA
WP_015245627.1\|2627020_2628718_+	hypothetical protein	NA	NA	NA	NA
WP_015245628.1\|2628881_2629835_-	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_015245629.1\|2629850_2630948_-	peptidoglycan-binding protein	NA	NA	NA	NA
WP_015245630.1\|2632248_2633373_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_015245631.1\|2633377_2634265_+	hypothetical protein	NA	NA	NA	NA
WP_015245632.1\|2634316_2635288_-	MoxR family ATPase	NA	NA	NA	NA
WP_015245633.1\|2635305_2637648_-	transglutaminase	NA	NA	NA	NA
WP_015245634.1\|2637637_2638984_-	DUF58 domain-containing protein	NA	NA	NA	NA
WP_015245635.1\|2639049_2639628_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_154673595.1\|2639783_2640140_-	hypothetical protein	NA	NA	NA	NA
WP_015245637.1\|2640324_2641008_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_020465533.1\|2641276_2641630_-	hypothetical protein	NA	NA	NA	NA
WP_015245638.1\|2642302_2643259_+	MoxR family ATPase	NA	NA	NA	NA
WP_015245639.1\|2643258_2644587_+	DUF58 domain-containing protein	NA	NA	NA	NA
WP_015245640.1\|2644609_2646469_+	DUF4129 domain-containing protein	NA	NA	NA	NA
WP_015245641.1\|2646520_2646979_-	hypothetical protein	NA	NA	NA	NA
WP_015245642.1\|2647316_2648045_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_015245644.1\|2650447_2651296_-	RNA polymerase sigma factor RpoD/SigA	F4YCU2	Synechococcus_phage	2.1e-17	30.7
WP_015245645.1\|2651298_2651610_-	hypothetical protein	NA	NA	NA	NA
WP_015245646.1\|2651720_2652629_-	hypothetical protein	NA	NA	NA	NA
WP_015245647.1\|2652727_2653333_-	hypothetical protein	NA	NA	NA	NA
WP_015245648.1\|2653707_2654697_-	hypothetical protein	NA	NA	NA	NA
WP_154673594.1\|2654910_2655111_-	hypothetical protein	NA	NA	NA	NA
WP_015244795.1\|2655832_2657302_-\|transposase	transposase	NA	NA	NA	NA
WP_015245650.1\|2657418_2658234_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_015243809.1\|2659645_2660890_+\|transposase	ISAzo13-like element ISSiac3 family transposase	NA	NA	NA	NA
WP_020465525.1\|2661703_2662105_+	hypothetical protein	NA	NA	NA	NA
WP_020465523.1\|2662619_2662922_-	hypothetical protein	NA	NA	NA	NA
WP_015245651.1\|2663037_2664366_+\|transposase	transposase	NA	NA	NA	NA
WP_015245652.1\|2664929_2666330_+	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_020465522.1\|2666703_2667045_+	hypothetical protein	NA	NA	NA	NA
WP_015244134.1\|2667309_2669514_+	recombinase family protein	NA	NA	NA	NA
WP_015245653.1\|2670052_2670289_+	DUF3006 domain-containing protein	NA	NA	NA	NA
WP_015245654.1\|2670285_2671224_+	MBL fold metallo-hydrolase	Q0H255	Geobacillus_phage	1.2e-29	33.5
WP_015245655.1\|2671404_2672163_+	hypothetical protein	NA	NA	NA	NA
WP_015245656.1\|2672164_2673778_+	hypothetical protein	NA	NA	NA	NA
WP_015245658.1\|2674389_2674941_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

2680370 : 2716166

Brevibacillus_phage(14.29%)

integrase,transposase

attL 2685756:2685770|attR 2728881:2728895

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015245665.1\|2680370_2681630_+\|integrase	tyrosine-type recombinase/integrase	A0A0K2CP59	Brevibacillus_phage	1.1e-09	25.8
WP_015245666.1\|2681626_2682592_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_015245667.1\|2682575_2683568_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_015244205.1\|2685075_2685462_-	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.4e-08	31.5
WP_015244204.1\|2685455_2685833_-	hypothetical protein	NA	NA	NA	NA
2685756:2685770	attL	NA	NA	NA	NA
WP_015245669.1\|2685858_2687235_+	hypothetical protein	NA	NA	NA	NA
WP_015245670.1\|2687244_2687733_+	hypothetical protein	NA	NA	NA	NA
WP_081578276.1\|2688081_2688801_-\|transposase	transposase	NA	NA	NA	NA
WP_015245671.1\|2689024_2692942_-	hypothetical protein	NA	NA	NA	NA
WP_015245672.1\|2694609_2695023_-	hypothetical protein	NA	NA	NA	NA
WP_026011897.1\|2695381_2696095_+\|transposase	transposase	NA	NA	NA	NA
WP_015245673.1\|2696015_2697233_+	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	2.3e-17	26.1
WP_015244135.1\|2697234_2698278_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_015245674.1\|2698378_2698861_+	hypothetical protein	NA	NA	NA	NA
WP_015244773.1\|2698954_2700379_+\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_015245676.1\|2701271_2702879_+\|transposase	transposase	NA	NA	NA	NA
WP_015245677.1\|2703115_2703988_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	5.0e-38	37.6
WP_015245678.1\|2703984_2705478_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_020467612.1\|2705810_2706206_-	hypothetical protein	A0A1I9LJR6	Stx_converting_phage	1.5e-13	35.3
WP_015244135.1\|2706310_2707354_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_081578412.1\|2707410_2707701_-	hypothetical protein	NA	NA	NA	NA
WP_174377931.1\|2708190_2708472_-	hypothetical protein	NA	NA	NA	NA
WP_020467617.1\|2709556_2710321_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_015245682.1\|2710489_2710741_+	hypothetical protein	NA	NA	NA	NA
WP_015245683.1\|2710727_2711276_+	hypothetical protein	NA	NA	NA	NA
WP_015245685.1\|2711993_2713595_+	phage/plasmid primase, P4 family, C-terminal domain-containing protein	K4HZY1	Acidithiobacillus_phage	7.4e-80	36.4
WP_015245686.1\|2714223_2714568_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_020467621.1\|2714646_2715267_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_015245687.1\|2715356_2716166_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.5e-09	31.5
2728881:2728895	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2832598 : 2899421

Paenibacillus_phage(14.29%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_052334748.1\|2832598_2832961_-\|transposase	transposase	NA	NA	NA	NA
WP_020466336.1\|2832918_2833374_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	4.6e-19	37.8
WP_081578311.1\|2833777_2834038_+\|transposase	transposase	NA	NA	NA	NA
WP_081578315.1\|2834135_2834432_-\|transposase	transposase	NA	NA	NA	NA
WP_081578316.1\|2834882_2834978_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015245777.1\|2835213_2836602_-	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_015245778.1\|2836951_2839444_-	DUF1549 domain-containing protein	NA	NA	NA	NA
WP_015245779.1\|2839634_2850740_-	Ig-like domain-containing protein	NA	NA	NA	NA
WP_015245782.1\|2851591_2852260_-	HAD family phosphatase	NA	NA	NA	NA
WP_015245783.1\|2852597_2852810_+	hypothetical protein	NA	NA	NA	NA
WP_020466332.1\|2852933_2854304_-	c-type cytochrome	NA	NA	NA	NA
WP_015245785.1\|2854665_2856507_+	hypothetical protein	NA	NA	NA	NA
WP_015245786.1\|2856717_2857713_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_015245787.1\|2857995_2858967_+	cysteine synthase family protein	NA	NA	NA	NA
WP_015245788.1\|2859028_2859451_+	YjbQ family protein	NA	NA	NA	NA
WP_015245789.1\|2859819_2861355_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_020466329.1\|2861481_2862159_-	hypothetical protein	NA	NA	NA	NA
WP_020466328.1\|2862176_2863025_-	WYL domain-containing protein	A0A0A8WJ41	Clostridium_phage	8.9e-16	38.1
WP_020466327.1\|2863216_2863708_+	CAP domain-containing protein	U5Q1E2	Bacillus_phage	1.6e-17	40.0
WP_015245791.1\|2863803_2864133_+	hypothetical protein	NA	NA	NA	NA
WP_015245793.1\|2865629_2865911_-	hypothetical protein	NA	NA	NA	NA
WP_015245795.1\|2867326_2868361_-	HTTM domain-containing protein	NA	NA	NA	NA
WP_015245796.1\|2868357_2868897_-	hypothetical protein	NA	NA	NA	NA
WP_015245797.1\|2869100_2870234_-	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_015245798.1\|2870617_2871787_+	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_015245799.1\|2871774_2873739_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_015245800.1\|2873785_2874499_+	DUF433 domain-containing protein	NA	NA	NA	NA
WP_154673714.1\|2875358_2878928_+	hypothetical protein	NA	NA	NA	NA
WP_015245802.1\|2878999_2879326_-	hypothetical protein	NA	NA	NA	NA
WP_015245803.1\|2879535_2881179_+	AarF/ABC1/UbiB kinase family protein	A0A2N9QVT9	Dishui_lake_phycodnavirus	5.0e-39	29.1
WP_015245804.1\|2881250_2883077_-	M56 family metallopeptidase	NA	NA	NA	NA
WP_015245805.1\|2883040_2883499_-	BlaI/MecI/CopY family transcriptional regulator	NA	NA	NA	NA
WP_015245806.1\|2884057_2885296_-	peptidase C45	NA	NA	NA	NA
WP_015245807.1\|2885404_2886967_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	7.3e-24	32.1
WP_015245808.1\|2887110_2887767_-	metallophosphoesterase family protein	NA	NA	NA	NA
WP_015245809.1\|2887777_2888617_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.5e-39	40.8
WP_044147536.1\|2888891_2889092_+	50S ribosomal protein L32	NA	NA	NA	NA
WP_015245811.1\|2889130_2889451_+	50S ribosomal protein L28	NA	NA	NA	NA
WP_015245812.1\|2889700_2889967_+	hypothetical protein	NA	NA	NA	NA
WP_015245813.1\|2890103_2891516_-	DUF1080 domain-containing protein	NA	NA	NA	NA
WP_015245814.1\|2891571_2892504_-	LssY C-terminal domain-containing protein	NA	NA	NA	NA
WP_015245815.1\|2892839_2894801_-	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	2.2e-94	41.9
WP_015245816.1\|2895167_2895878_-	5,6-dimethylbenzimidazole synthase	NA	NA	NA	NA
WP_015245817.1\|2895895_2897410_-	protoporphyrinogen oxidase	NA	NA	NA	NA
WP_015245818.1\|2897439_2898378_-	ferrochelatase	NA	NA	NA	NA
WP_015245819.1\|2898527_2899421_-\|protease	M48 family metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_7

2911825 : 2987307

Hokovirus(33.33%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_086018129.1\|2911825_2913215_+\|transposase	ISKra4-like element ISSiac4 family transposase	NA	NA	NA	NA
WP_015245831.1\|2913200_2913386_-	hypothetical protein	NA	NA	NA	NA
WP_015245832.1\|2913436_2915149_-	50S ribosome-binding GTPase	NA	NA	NA	NA
WP_015245833.1\|2915145_2917005_-	hypothetical protein	NA	NA	NA	NA
WP_015245834.1\|2917035_2918736_-	M2 family metallopeptidase	NA	NA	NA	NA
WP_015245835.1\|2918894_2919605_-	hypothetical protein	NA	NA	NA	NA
WP_015245836.1\|2919604_2920705_-	hypothetical protein	NA	NA	NA	NA
WP_154673712.1\|2921394_2921562_-	hypothetical protein	NA	NA	NA	NA
WP_154673711.1\|2921634_2921826_-	hypothetical protein	NA	NA	NA	NA
WP_015245838.1\|2921953_2922724_+	HAD family hydrolase	NA	NA	NA	NA
WP_015245839.1\|2922870_2923755_-	hypothetical protein	NA	NA	NA	NA
WP_015245840.1\|2924082_2925504_+	two-component sensor histidine kinase	A0A1V0SGX0	Hokovirus	7.9e-09	25.8
WP_015245841.1\|2925500_2926889_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_020466309.1\|2927000_2927537_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_015245843.1\|2928012_2931291_+	hypothetical protein	NA	NA	NA	NA
WP_015245844.1\|2931722_2933327_-	glycosyltransferase family 39 protein	NA	NA	NA	NA
WP_026012014.1\|2934986_2937305_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015245848.1\|2937375_2937969_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_154673710.1\|2937965_2938781_-	hypothetical protein	NA	NA	NA	NA
WP_015245850.1\|2939399_2941109_-	phosphate porin	NA	NA	NA	NA
WP_015245852.1\|2941951_2943694_-	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_015245853.1\|2944070_2945351_-	citrate synthase	NA	NA	NA	NA
WP_015245854.1\|2945622_2946564_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_015245855.1\|2946900_2948328_+	sulfatase	NA	NA	NA	NA
WP_015245856.1\|2948445_2949285_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_154673709.1\|2949796_2950261_+	hypothetical protein	NA	NA	NA	NA
WP_015245858.1\|2950469_2950871_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015245859.1\|2952033_2953314_+	acyltransferase	NA	NA	NA	NA
WP_015245860.1\|2953483_2954707_+	DUF2029 domain-containing protein	NA	NA	NA	NA
WP_015245861.1\|2954669_2955482_-	SDR family oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	2.6e-25	31.1
WP_154673707.1\|2955523_2957305_-	c-type cytochrome	NA	NA	NA	NA
WP_020466299.1\|2957985_2959038_+	metallophosphoesterase	NA	NA	NA	NA
WP_015245864.1\|2959160_2959514_-	hypothetical protein	NA	NA	NA	NA
WP_015245865.1\|2959920_2961498_-	methyltransferase regulatory domain-containing protein	NA	NA	NA	NA
WP_015245866.1\|2962009_2964067_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	1.9e-27	24.5
WP_015245867.1\|2964210_2964882_+	hypothetical protein	NA	NA	NA	NA
WP_015245868.1\|2964886_2965177_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_020466297.1\|2965359_2966586_+	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_015245870.1\|2966634_2967642_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_015245871.1\|2967811_2969638_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_015245872.1\|2969643_2970129_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_015245873.1\|2970307_2970790_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_015245874.1\|2970945_2972439_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_015245875.1\|2972440_2972965_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_015245876.1\|2973185_2975075_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_015245877.1\|2975077_2975938_-	secretion protein	NA	NA	NA	NA
WP_154673705.1\|2976576_2977911_+	FHA domain-containing protein	NA	NA	NA	NA
WP_015245879.1\|2977925_2979344_-	hypothetical protein	NA	NA	NA	NA
WP_015245880.1\|2979370_2979997_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_015245881.1\|2980006_2981401_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_015245882.1\|2981827_2985772_+	hypothetical protein	NA	NA	NA	NA
WP_015243913.1\|2985963_2987307_+\|transposase	IS4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

5130106 : 5196843

Salmonella_phage(20.0%)

protease,integrase,transposase

attL 5133203:5133219|attR 5175898:5175914

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015247452.1\|5130106_5130787_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
WP_020467588.1\|5130783_5131140_-	hypothetical protein	NA	NA	NA	NA
WP_154673940.1\|5131224_5132655_-	cytochrome B6	NA	NA	NA	NA
WP_015247455.1\|5132892_5133531_-	HD domain-containing protein	NA	NA	NA	NA
5133203:5133219	attL	NA	NA	NA	NA
WP_015247456.1\|5133589_5134633_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_015247457.1\|5135036_5135777_+	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_015247458.1\|5135842_5136655_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_015247459.1\|5136680_5137214_-	hypothetical protein	NA	NA	NA	NA
WP_015247460.1\|5137170_5139354_-	aminotransferase class III-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_015247461.1\|5139361_5141218_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_015247462.1\|5141171_5142098_-	phosphatidylserine decarboxylase	NA	NA	NA	NA
WP_015247463.1\|5142094_5143591_-	GMC family oxidoreductase	NA	NA	NA	NA
WP_015247464.1\|5144127_5144577_+	hypothetical protein	NA	NA	NA	NA
WP_020467582.1\|5145841_5146120_-\|transposase	transposase	NA	NA	NA	NA
WP_015247465.1\|5146310_5146664_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_161625863.1\|5146749_5147895_+\|protease	Clp protease	NA	NA	NA	NA
WP_015247467.1\|5147906_5149598_+	DUF3327 domain-containing protein	NA	NA	NA	NA
WP_020467581.1\|5149879_5150182_-	hypothetical protein	NA	NA	NA	NA
WP_020467580.1\|5150210_5150552_+	hypothetical protein	NA	NA	NA	NA
WP_015247468.1\|5150798_5151746_+	hypothetical protein	NA	NA	NA	NA
WP_015247469.1\|5151742_5152534_+	hypothetical protein	NA	NA	NA	NA
WP_020467579.1\|5152623_5153181_+	hypothetical protein	NA	NA	NA	NA
WP_086018138.1\|5153210_5153732_-	recombinase family protein	A0A1S6L009	Salmonella_phage	1.8e-22	49.6
WP_020467577.1\|5153634_5154522_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_015247471.1\|5155006_5155324_+	hypothetical protein	NA	NA	NA	NA
WP_015247472.1\|5155534_5156155_-	DUF1801 domain-containing protein	NA	NA	NA	NA
WP_015247473.1\|5156418_5157204_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_015247474.1\|5157302_5157923_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_015247475.1\|5158214_5159231_-	agmatinase	NA	NA	NA	NA
WP_015247476.1\|5159995_5160247_+	hypothetical protein	NA	NA	NA	NA
WP_015247478.1\|5161047_5161491_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_015247479.1\|5161557_5162193_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_015247480.1\|5162314_5163106_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	3.8e-21	32.8
WP_015247481.1\|5163231_5163963_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_015247482.1\|5164397_5165513_+	hypothetical protein	NA	NA	NA	NA
WP_015247483.1\|5166242_5166806_+	hypothetical protein	NA	NA	NA	NA
WP_015247484.1\|5166942_5170611_-	protein kinase	A0A2R8FE23	Brazilian_cedratvirus	4.0e-12	24.8
WP_015247485.1\|5170607_5171240_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_015247486.1\|5171628_5178234_+	cadherin domain-containing protein	M1UGR9	Cyanophage	2.0e-09	34.2
5175898:5175914	attR	NA	NA	NA	NA
WP_015247487.1\|5179335_5180463_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_015247488.1\|5181784_5182822_+	hypothetical protein	NA	NA	NA	NA
WP_154673934.1\|5183012_5184104_+	hypothetical protein	NA	NA	NA	NA
WP_015247490.1\|5184251_5185199_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_015247492.1\|5185707_5186268_-	sugar O-acetyltransferase	NA	NA	NA	NA
WP_015247493.1\|5187053_5188856_+	hypothetical protein	NA	NA	NA	NA
WP_015247494.1\|5188975_5189239_+	hypothetical protein	NA	NA	NA	NA
WP_015247495.1\|5189491_5189965_+	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_015247496.1\|5190048_5190654_-	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	1.8e-15	37.7
WP_015247497.1\|5190853_5191672_-	BON domain-containing protein	NA	NA	NA	NA
WP_015247498.1\|5192000_5192702_-	hypothetical protein	NA	NA	NA	NA
WP_015247499.1\|5193002_5194799_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015244219.1\|5195682_5196843_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

5213683 : 5268556

Pseudomonas_phage(25.0%)

terminase,head,transposase,protease,portal,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020467514.1\|5213683_5215048_-\|capsid	phage major capsid protein	A0A2D1GNH4	Pseudomonas_phage	9.3e-07	24.1
WP_015247517.1\|5215207_5216563_-\|head,protease	HK97 family phage prohead protease	NA	NA	NA	NA
WP_015247518.1\|5216642_5217056_-	hypothetical protein	NA	NA	NA	NA
WP_015247519.1\|5217883_5218186_-	hypothetical protein	NA	NA	NA	NA
WP_157579443.1\|5218175_5220845_-\|portal	phage portal protein	NA	NA	NA	NA
WP_015247521.1\|5221236_5222613_-\|terminase	phage terminase large subunit	A0A0R8VCM7	Thermobifida_phage	1.6e-110	50.1
WP_020467516.1\|5222609_5223131_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015247522.1\|5223156_5223408_-	hypothetical protein	NA	NA	NA	NA
WP_044147238.1\|5225176_5225662_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_015247523.1\|5225719_5226442_-	hypothetical protein	NA	NA	NA	NA
WP_015247524.1\|5226444_5227227_-	TIGR04255 family protein	NA	NA	NA	NA
WP_015247525.1\|5227565_5227988_-	hypothetical protein	NA	NA	NA	NA
WP_015247526.1\|5228029_5228464_-	hypothetical protein	NA	NA	NA	NA
WP_015247527.1\|5228460_5229291_-	TIGR04255 family protein	NA	NA	NA	NA
WP_015247528.1\|5229584_5229740_-	hypothetical protein	NA	NA	NA	NA
WP_015247529.1\|5229736_5230060_-	hypothetical protein	NA	NA	NA	NA
WP_020467520.1\|5230143_5230353_-	hypothetical protein	NA	NA	NA	NA
WP_015247531.1\|5230349_5230817_-	hypothetical protein	NA	NA	NA	NA
WP_015247532.1\|5230813_5231023_-	hypothetical protein	NA	NA	NA	NA
WP_015247533.1\|5231026_5231923_-	hypothetical protein	NA	NA	NA	NA
WP_015247534.1\|5231919_5232459_-	hypothetical protein	NA	NA	NA	NA
WP_015247535.1\|5232455_5232674_-	hypothetical protein	NA	NA	NA	NA
WP_015247536.1\|5232905_5233106_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015247537.1\|5233279_5233840_+	hypothetical protein	NA	NA	NA	NA
WP_015247538.1\|5233943_5235506_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_015247539.1\|5235517_5235724_-	hypothetical protein	NA	NA	NA	NA
WP_015247540.1\|5236350_5236611_+	hypothetical protein	NA	NA	NA	NA
WP_015247541.1\|5236710_5237097_+	hypothetical protein	NA	NA	NA	NA
WP_015247543.1\|5237587_5237956_+	hypothetical protein	NA	NA	NA	NA
WP_015247544.1\|5237955_5238582_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_015247545.1\|5238865_5241205_+	bifunctional DNA primase/polymerase	A0A1P8DTT9	Salmonella_phage	4.4e-49	37.5
WP_015247546.1\|5241340_5241685_+	hypothetical protein	NA	NA	NA	NA
WP_015247547.1\|5241681_5241945_+	hypothetical protein	NA	NA	NA	NA
WP_015247548.1\|5241941_5242241_+	hypothetical protein	NA	NA	NA	NA
WP_015247549.1\|5242609_5243047_-	hypothetical protein	NA	NA	NA	NA
WP_015247550.1\|5243098_5244055_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_020467522.1\|5244459_5244855_+\|transposase	transposase	NA	NA	NA	NA
WP_015247551.1\|5245426_5246446_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_015247552.1\|5246585_5247590_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_015247553.1\|5248040_5249258_+	hypothetical protein	NA	NA	NA	NA
WP_015247554.1\|5249702_5250434_+	hypothetical protein	NA	NA	NA	NA
WP_015247555.1\|5250822_5251044_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_015247556.1\|5251108_5251753_+	hypothetical protein	NA	NA	NA	NA
WP_020467525.1\|5252783_5253485_+	hypothetical protein	NA	NA	NA	NA
WP_015247560.1\|5253974_5254550_+	hypothetical protein	NA	NA	NA	NA
WP_015247562.1\|5254987_5255599_-	hypothetical protein	NA	NA	NA	NA
WP_015247563.1\|5255917_5256088_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015247565.1\|5256569_5257007_+	hypothetical protein	NA	NA	NA	NA
WP_015247567.1\|5257688_5257997_+	hypothetical protein	NA	NA	NA	NA
WP_015247568.1\|5258187_5259213_+	DUF1254 domain-containing protein	A0A2P0VP21	Tetraselmis_virus	9.3e-52	38.2
WP_020467528.1\|5259269_5259407_+	hypothetical protein	NA	NA	NA	NA
WP_154673930.1\|5259538_5259850_-	hypothetical protein	NA	NA	NA	NA
WP_015247569.1\|5259861_5260962_-	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_015247570.1\|5261058_5261694_-	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_015247571.1\|5262448_5263378_-	S1/P1 nuclease	NA	NA	NA	NA
WP_015247572.1\|5263536_5264439_-	hypothetical protein	NA	NA	NA	NA
WP_015247573.1\|5265338_5265917_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_015247574.1\|5266263_5266587_+	H-type lectin domain-containing protein	NA	NA	NA	NA
WP_015247575.1\|5267366_5267702_-	hypothetical protein	NA	NA	NA	NA
WP_015247576.1\|5268136_5268556_+\|protease	protease inhibitor I42 family protein	NA	NA	NA	NA

DBSCAN-SWA_10

5581725 : 5641514

Acanthamoeba_polyphaga_lentillevirus(14.29%)

transposase,protease,integrase,tail,capsid

attL 5627273:5627318|attR 5641657:5641702

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015247801.1\|5581725_5582280_+\|protease	hydrogenase maturation protease	NA	NA	NA	NA
WP_015247803.1\|5582440_5582770_+	hydrogenase maturation nickel metallochaperone HypA	NA	NA	NA	NA
WP_015247804.1\|5582769_5583666_+	hydrogenase nickel incorporation protein HypB	NA	NA	NA	NA
WP_015247805.1\|5583830_5584769_+	3-methyladenine DNA glycosylase	NA	NA	NA	NA
WP_015247806.1\|5586300_5587407_+	slipin family protein	J3IZE5	Acanthamoeba_polyphaga_lentillevirus	2.4e-13	22.1
WP_015247807.1\|5587507_5588734_-	GTP-binding protein	NA	NA	NA	NA
WP_015247808.1\|5588771_5588948_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_015247809.1\|5589177_5590803_-	permease	NA	NA	NA	NA
WP_015247810.1\|5590799_5591651_-	hypothetical protein	NA	NA	NA	NA
WP_015247812.1\|5592110_5592479_-	hypothetical protein	NA	NA	NA	NA
WP_015247813.1\|5592937_5596294_+	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_015247815.1\|5597391_5600949_-	AAA family ATPase	NA	NA	NA	NA
WP_015247816.1\|5600962_5602210_-	DNA repair exonuclease	NA	NA	NA	NA
WP_015247817.1\|5602307_5604401_-	exodeoxyribonuclease V subunit alpha	A0A1P8DII4	Virus_Rctr197k	7.5e-24	26.1
WP_015247818.1\|5604397_5608111_-	UvrD-helicase domain-containing protein	A0A068EQC7	Bacillus_phage	2.4e-12	22.1
WP_015247819.1\|5608107_5611566_-	exodeoxyribonuclease V subunit gamma	NA	NA	NA	NA
WP_015247820.1\|5612244_5612445_+	hypothetical protein	NA	NA	NA	NA
WP_015247821.1\|5612737_5613034_-	hypothetical protein	NA	NA	NA	NA
WP_015247822.1\|5613435_5613708_+	hypothetical protein	NA	NA	NA	NA
WP_015247823.1\|5613710_5614160_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_015247824.1\|5614669_5615983_+	MgtC/SapB family protein	NA	NA	NA	NA
WP_015247825.1\|5616166_5616637_-	hypothetical protein	NA	NA	NA	NA
WP_015247827.1\|5617528_5617840_-	hypothetical protein	NA	NA	NA	NA
WP_015247829.1\|5618374_5618710_-	hypothetical protein	NA	NA	NA	NA
WP_015247830.1\|5618846_5619089_+	hypothetical protein	NA	NA	NA	NA
WP_015247831.1\|5619168_5620206_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_015247832.1\|5620982_5622035_+	DUF1559 domain-containing protein	NA	NA	NA	NA
WP_015247833.1\|5622080_5622500_+	hypothetical protein	NA	NA	NA	NA
WP_052315660.1\|5622769_5623033_-\|transposase	transposase	NA	NA	NA	NA
WP_015247834.1\|5623248_5625057_-	RNA-directed DNA polymerase	NA	NA	NA	NA
WP_154673869.1\|5625053_5625968_-	hypothetical protein	NA	NA	NA	NA
5627273:5627318	attL	NA	NA	NA	NA
WP_015247836.1\|5627419_5627896_-	hypothetical protein	NA	NA	NA	NA
WP_015247837.1\|5627892_5628309_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_015247838.1\|5628416_5628740_+	hypothetical protein	NA	NA	NA	NA
WP_015247839.1\|5628732_5629104_+	HNH endonuclease	H9YSB8	environmental_Halophage	7.6e-12	41.3
WP_015247840.1\|5629388_5630492_+\|capsid	phage major capsid protein	A0A2I5ARA4	Synechococcus_phage	9.1e-45	35.0
WP_015247841.1\|5630551_5630794_+	hypothetical protein	NA	NA	NA	NA
WP_015247842.1\|5630809_5631229_+	hypothetical protein	NA	NA	NA	NA
WP_015247843.1\|5631241_5631604_+	hypothetical protein	NA	NA	NA	NA
WP_015247844.1\|5631608_5631836_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015247845.1\|5631838_5632189_+\|tail	phage tail assembly chaperone family protein, TAC	A0A0R8VCP4	Thermobifida_phage	1.0e-05	34.3
WP_015247846.1\|5632281_5634198_+\|tail	phage tail tape measure protein	NA	NA	NA	NA
WP_015247847.1\|5634823_5635135_-	hypothetical protein	NA	NA	NA	NA
WP_020467217.1\|5635757_5636396_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015247850.1\|5636538_5636760_+	hypothetical protein	NA	NA	NA	NA
WP_015247851.1\|5636913_5637135_+	hypothetical protein	NA	NA	NA	NA
WP_015247852.1\|5637282_5637600_+	hypothetical protein	NA	NA	NA	NA
WP_015247853.1\|5637606_5639304_+	AAA family ATPase	A0A2D2W3B7	Mycobacterium_phage	2.1e-08	29.1
WP_015247854.1\|5639535_5639919_+	hypothetical protein	NA	NA	NA	NA
WP_015247855.1\|5639911_5640106_+	hypothetical protein	NA	NA	NA	NA
WP_015247856.1\|5640102_5640348_+	transcriptional regulator	NA	NA	NA	NA
WP_015247857.1\|5640350_5641514_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
5641657:5641702	attR	NA	NA	NA	NA

DBSCAN-SWA_11

6744735 : 6754850

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015248651.1\|6744735_6746802_-	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	H8ZJI5	Ostreococcus_tauri_virus	1.7e-108	44.3
WP_015248652.1\|6747100_6748129_-	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	1.4e-68	46.2
WP_015248653.1\|6748637_6748931_+	carbon storage regulator	A0A2I7RT00	Vibrio_phage	1.4e-05	55.3
WP_015248654.1\|6748869_6749577_-	winged helix-turn-helix domain-containing protein	W8CYM9	Bacillus_phage	4.8e-31	37.1
WP_015248655.1\|6749706_6750564_-	phosphate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.8e-17	29.4
WP_015248656.1\|6750569_6751523_-	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_015248657.1\|6751519_6752479_-	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_015248658.1\|6752475_6753447_-	PstS family phosphate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_015248659.1\|6753560_6754850_-	PAS-domain containing protein	W8CYF6	Bacillus_phage	3.4e-35	35.6

DBSCAN-SWA_12

7533536 : 7606594

Leptospira_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_086018153.1\|7533536_7534926_+\|transposase	ISKra4-like element ISSiac4 family transposase	NA	NA	NA	NA
WP_015249195.1\|7535097_7536762_+	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_020466951.1\|7536806_7538273_-	sulfatase-like hydrolase/transferase	A0A2K9L727	Tupanvirus	5.0e-14	24.8
WP_015249197.1\|7538469_7539942_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_015249198.1\|7540322_7542512_+	S9 family peptidase	NA	NA	NA	NA
WP_015249199.1\|7542687_7543011_+	hypothetical protein	NA	NA	NA	NA
WP_015249200.1\|7543007_7544681_+	sodium transporter	NA	NA	NA	NA
WP_015249201.1\|7544727_7546218_+	M81 family metallopeptidase	NA	NA	NA	NA
WP_015249202.1\|7546217_7547072_+	carbon-nitrogen hydrolase family protein	M1I0W4	Acanthocystis_turfacea_Chlorella_virus	5.1e-19	29.9
WP_015249203.1\|7547078_7547513_+	DUF2809 domain-containing protein	NA	NA	NA	NA
WP_015249204.1\|7547567_7548827_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_015249205.1\|7549170_7550586_-	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_015249206.1\|7550616_7553934_-	DUF1553 domain-containing protein	NA	NA	NA	NA
WP_015249207.1\|7554266_7555223_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_015249208.1\|7555224_7555827_-	hypothetical protein	NA	NA	NA	NA
WP_154673834.1\|7555936_7557997_-	pilus assembly protein N-terminal domain-containing protein	NA	NA	NA	NA
WP_015249210.1\|7558475_7559234_+	3-oxoacyl-ACP reductase FabG	NA	NA	NA	NA
WP_015249211.1\|7559411_7561406_+	hypothetical protein	NA	NA	NA	NA
WP_015249212.1\|7561607_7562480_+	hypothetical protein	NA	NA	NA	NA
WP_015249213.1\|7562667_7564350_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_015249214.1\|7564478_7565408_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.8e-23	31.2
WP_015249215.1\|7565422_7568149_-	hypothetical protein	NA	NA	NA	NA
WP_015249216.1\|7568332_7571203_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	1.0e-244	45.5
WP_015249217.1\|7571826_7572492_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_015249218.1\|7572752_7574009_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_015249219.1\|7574120_7577852_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.9e-14	21.2
WP_015249220.1\|7577909_7581287_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.3e-12	18.4
WP_015249221.1\|7581396_7582041_-	hypothetical protein	NA	NA	NA	NA
WP_015249222.1\|7582063_7584232_-	xanthine dehydrogenase family protein molybdopterin-binding subunit	NA	NA	NA	NA
WP_015249223.1\|7584228_7584699_-	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_015249224.1\|7585080_7585560_-	hypothetical protein	NA	NA	NA	NA
WP_015249225.1\|7585967_7587347_-	magnesium transporter	NA	NA	NA	NA
WP_015249226.1\|7587886_7588735_-	DUF1080 domain-containing protein	NA	NA	NA	NA
WP_015249228.1\|7590414_7590588_-	Flp family type IVb pilin	NA	NA	NA	NA
WP_015249229.1\|7591243_7591573_+\|transposase	transposase	NA	NA	NA	NA
WP_015249230.1\|7591545_7592181_+\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	7.1e-18	31.8
WP_015249231.1\|7592345_7593044_+	hypothetical protein	NA	NA	NA	NA
WP_044147849.1\|7593152_7593893_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_166443201.1\|7594460_7594811_-	DUF952 domain-containing protein	NA	NA	NA	NA
WP_020466962.1\|7595944_7596247_+	hypothetical protein	NA	NA	NA	NA
WP_015244135.1\|7596526_7597570_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_015249238.1\|7597876_7598080_+	hypothetical protein	NA	NA	NA	NA
WP_015249239.1\|7598412_7599192_-	hypothetical protein	NA	NA	NA	NA
WP_020466964.1\|7600323_7600707_-	hypothetical protein	NA	NA	NA	NA
WP_020466965.1\|7600869_7601859_-\|transposase	transposase	NA	NA	NA	NA
WP_015249244.1\|7603100_7603784_+	hypothetical protein	NA	NA	NA	NA
WP_015249245.1\|7604065_7604410_-	DUF952 domain-containing protein	NA	NA	NA	NA
WP_015249246.1\|7604406_7605045_-	DUF4291 domain-containing protein	NA	NA	NA	NA
WP_020466969.1\|7605137_7605530_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_015249248.1\|7605766_7606594_-\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	6.2e-22	29.0

DBSCAN-SWA_13

7849360 : 7866475

Salmonella_virus(33.33%)

bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157579472.1\|7849360_7849612_-\|transposase	transposase	NA	NA	NA	NA
WP_015249428.1\|7850744_7852151_-\|transposase	IS66 family transposase	NA	NA	NA	NA
WP_015249431.1\|7853799_7854960_+\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_015249432.1\|7855652_7856918_+	hypothetical protein	NA	NA	NA	NA
WP_154673842.1\|7857221_7857626_-	hypothetical protein	NA	NA	NA	NA
WP_154673843.1\|7858168_7858411_-	hypothetical protein	NA	NA	NA	NA
WP_015249433.1\|7858919_7859594_+\|bacteriocin	bacteriocin/lantibiotic ABC transporter	NA	NA	NA	NA
WP_015249434.1\|7859665_7860754_+	DUF1573 domain-containing protein	NA	NA	NA	NA
WP_020467035.1\|7861385_7862171_-\|transposase	transposase	NA	NA	NA	NA
WP_026012116.1\|7862145_7862508_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015249435.1\|7862792_7863890_+	acyltransferase	A0A1R3Y5Q6	Salmonella_virus	8.5e-19	27.8
WP_015249436.1\|7864015_7864393_+	hypothetical protein	NA	NA	NA	NA
WP_015249437.1\|7864386_7864773_+	IS66 family insertion sequence element accessory protein TnpB	S5VXZ8	Leptospira_phage	1.1e-08	31.5
WP_015249438.1\|7864804_7866475_+\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	2.7e-56	33.7

DBSCAN-SWA_14

9142080 : 9203265

uncultured_Mediterranean_phage(33.33%)

integrase,transposase

attL 9197060:9197112|attR 9198414:9198466

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015244411.1\|9142080_9143319_-\|transposase	IS701-like element ISSiac1 family transposase	NA	NA	NA	NA
WP_015250330.1\|9143567_9148451_-	DUF4082 domain-containing protein	A0A1B1IPM9	uncultured_Mediterranean_phage	1.1e-12	34.2
WP_015250331.1\|9148965_9149895_+	cation transporter	NA	NA	NA	NA
WP_015250332.1\|9150152_9153032_+	DUF1553 domain-containing protein	NA	NA	NA	NA
WP_015250333.1\|9153154_9154660_+	DUF1501 domain-containing protein	NA	NA	NA	NA
WP_157579517.1\|9155246_9156863_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_015250334.1\|9157101_9159234_+	HEAT repeat domain-containing protein	NA	NA	NA	NA
WP_015250335.1\|9159309_9160431_+	VWA domain-containing protein	NA	NA	NA	NA
WP_015250336.1\|9160559_9161267_+	response regulator transcription factor	NA	NA	NA	NA
WP_015250337.1\|9161263_9163009_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.4e-10	23.2
WP_015250338.1\|9163112_9164441_+	DUF3386 family protein	NA	NA	NA	NA
WP_015250339.1\|9164569_9166279_-	hypothetical protein	NA	NA	NA	NA
WP_015250340.1\|9166630_9167470_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	9.3e-50	43.5
WP_015250341.1\|9167618_9168632_-	diacylglycerol kinase	NA	NA	NA	NA
WP_015250342.1\|9168816_9169389_-	hypothetical protein	NA	NA	NA	NA
WP_015250344.1\|9169768_9170827_+	isocitrate dehydrogenase	NA	NA	NA	NA
WP_015250345.1\|9171000_9171309_-	hypothetical protein	NA	NA	NA	NA
WP_015250346.1\|9171484_9173305_-	hypothetical protein	NA	NA	NA	NA
WP_015250347.1\|9173599_9174247_-	hypothetical protein	NA	NA	NA	NA
WP_015250348.1\|9174287_9175898_-	TolC family protein	NA	NA	NA	NA
WP_015250349.1\|9176069_9177428_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_015250350.1\|9177424_9180673_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_157579479.1\|9181028_9181439_-	hypothetical protein	NA	NA	NA	NA
WP_015250352.1\|9181939_9182524_+	hypothetical protein	NA	NA	NA	NA
WP_015250353.1\|9182539_9182905_-	hypothetical protein	NA	NA	NA	NA
WP_081578334.1\|9182954_9183623_-	ThuA domain-containing protein	NA	NA	NA	NA
WP_015250354.1\|9183799_9185419_-	sialate O-acetylesterase	NA	NA	NA	NA
WP_015250355.1\|9185671_9185914_+	hypothetical protein	NA	NA	NA	NA
WP_015250356.1\|9186535_9187132_+	hypothetical protein	NA	NA	NA	NA
WP_015250357.1\|9187244_9188903_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_015250359.1\|9189947_9192893_+	right-handed parallel beta-helix repeat-containing protein	NA	NA	NA	NA
WP_015250360.1\|9192960_9194553_-	alkaline phosphatase D family protein	NA	NA	NA	NA
WP_015250361.1\|9195445_9196684_-\|transposase	IS701 family transposase	NA	NA	NA	NA
9197060:9197112	attL	NA	NA	NA	NA
WP_044147311.1\|9197118_9197805_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_015250362.1\|9198534_9199851_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
9198414:9198466	attR	NA	NA	NA	NA
WP_015250364.1\|9200725_9201871_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_020466612.1\|9202160_9202349_-	hypothetical protein	NA	NA	NA	NA
WP_161625818.1\|9202527_9203265_+\|transposase	IS66 family transposase zinc-finger binding domain-containing protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NC_019892.1|WP_157579443.1|5218175_5220845_-|phage-portal-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_019892.1|WP_157579443.1|5218175_5220845_-|phage-portal-protein

5218175_5220845_-

889 aa aa

5213683-5268556

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_019892_18	Orphan	18.1\|5369118\|49\|NC_019892\|CRISPRCasFinder	5369118-5369166	49	5262004-5261956	2

1. spacer 18.1|5369118|49|NC_019892|CRISPRCasFinder matches to NC_019892 position: 5262004-5261956, mismatch: 2

ttctagccaggggtgaaacccctgggaaaggttcgacatatgagtgctc	CRISPR spacer
ttctagccaggggtgaaacccctgggaaatgttcgacatatgagtgttc	Protospacer
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