CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_015949	Caldicellulosiruptor lactoaceticus 6A, complete sequence	12 crisprs	cas14k,Cas14b_CAS-V-F,csa3,cas3,cas6,DEDDh,cas2,cas1,cas4,csc1gr5,csc2gr7,cas10d,WYL,cas14j,cas5,cas7b,cas8b1,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,csx20,cas7,csm6,csx10gr5	0	24	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_015949_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_1

1695607-1699780

TypeI-D

Consensus_repeat	Method
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CRISPRCasFinder
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CRT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	PILER-CR

57 spacers

cas2,cas1,cas4,cas6,cas3,csc1gr5,csc2gr7,cas10d,WYL

The CRISPR arrays of NC_015949_1

>merge|NC_015949|1|1695607-1699780|CRISPRCasFinder,CRT,PILER-CR
GTTTTAACCCCTCTTAAGTGGAGAATCTTTTCAACCTCCCTTCCGATTTCTGCCAGTCCCCACACATCCAGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAGCAGGATTGGCAACCGCAGCGGTAGGCCCTCTTTTAAAGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACGTATTGCAGGCGTAACAGAAGTTAAATCATACATATGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACACATCATTATACGCATATACCACATTACTAGCACTTGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCCTTCTTATCGTCTGCCTTAAGCTTTGGATAAAATCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAACCAAACCCGCCACAAGAGATGAATACATTAGAGCTTTCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTTTATCTTTTCAGTTTTTATATATAATAAATTGTTTTAAGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAAGAAAAAATGGGTACTGAACATCCAGCATTAAAACGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAACCAGATAACATTGTCGATTTCCCGTTTTTTCTGGCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTCAATATCATCTGCATATAACGTATTTTGCTCTAAATGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCTGTTCCCTGCGATGTATATATGTCAATACCAAGTTTGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTCAATATCATCTGCATATAACGTATTTTGCTCTAAATGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACGCAGAACAGTAACTGTATCAAGCGGCTCTATTTTGTGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACGAATAAAGGAGACAGAAAAGGCAGTACAGATAAGAATGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTTAATTTGGCTTGAAGGAAGAAGAGTATTATTTATACGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTTATTGTTGTTTGTACAACATTAAATGCCGCTCTTACGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAACGTCTTTCATATCAGCACCGTCTAAAGCACCTGGCAAAATCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTTTATAGAGGAGTAGACACCTACTCCTCTGTAGCCGTTTTAATCCCTTTAAGGGAAGAATCTTCCCAACGAGCTGCTGCTATACAGTTCTTCGCTAAACTCTGCCTTGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTACATAGATTTTAAAAACATAAGTCCCGAAGTTTTTACGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTGTACTCGTTAGCTTTTCAATTATACTATCCTCATTCAGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCTCATCATAAAGCACACAAGCAATATACTGAACATCCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCCCTACTTTGCAATACCCTTAAAAAATCTGACAGCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCTCATCATAAAGCACACAAGCAATATACTGAACATCCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAGAAAGAAGGTGGTTTAATATGGCACTAACTGCACAGCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTAAAAGAAAAAAACGACAAATAGTAGAAGTTTGTTATGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAATCGTCAAAACTTCACCGTGATAAAGTGATGAACGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTAGTTATTGTTGCCTGCACAACACTAAATGCAGCTTTAACGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTTCCCCATAGCTGGTCTTGCAGCAATAATGTATAAGCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACATCATAACAGGTTTAAGACTATGTTTTGCAATAACTTCCTTGATGTAGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCTTCTTGGGTTGGTGGACTTGTATGTATACTGTTATGAGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACGGCAGTAGCACAGGCGGTTAAGAGTGCGATTGCAACGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACGCCAAGGACAGAATTTATTTACCAACCGATTTATGGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACGTATTTTAGAAATGTATCAACACAAAAAAGCCAAGCTTGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTTCAAAGAAAAACAAGCGAGCAACAAGTTGTATCAATTGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACACCGCCCAGCAAAACGTTCATCGCTCTTATCTTTTCCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACGGAAAGAGTGGTTTACAGTGTCCAATCAAACGCTTCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCGAACAATGTCCTTGTAAATACAGCTACCAGATTAAAAGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTTGAGGTAAGAGGAGCTTCGGCTCTAACCGCAACATATGGGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTGATATGCTTTTAAAAGCTGAAAGGCAATGTTAAGTTGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAAAAACTAAAACCAATTAACCACAAGATTTTGGCTATTACGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCTGAACAATCACTCAAATAACACTTTATTTTTCCTTTCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACGATTTTAATCACTATTTTAGGCACTTCGGCATAGCGTTGTTTTAATCCCTCTTTAGGGAAGAATCTTCCCAACTCCGCCAGAGCCACTTGTTATTGGCTTCAATGTTCGAGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAATTACAGAACGGCATATTGGAACAGGAATTAAAGCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTTGGTTTAAACTTCTTAGAAAGTCTGGATTATAGTGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTATGAAATAATACACCCTCGCAAGCCAAAACGAAAGATGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCTTCAAAACGAGAAGGAAGAATATTAGAAGGATTTGACCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACGTTGCAAGAAAAGTTACTGTTAGAACGTTTGTAGCTTATAGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTACACCTTCAAGAATTGTCTCTTCTTTTGACATTTTATGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCTGCCACGGGAGTTTAGGATACTCTAACCCTTCATTAATGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCTTATCCCTTCCCATGCACCTTTCCAATCACCTTTAATAATGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAACTGCCAAGCGGAATTGGTATTATTGAGCTGGTAGAGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACCTTCAAAACGAGAAGGAAGAATATTAGAAGGATTTGACCGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAGCTCTTTTATTAAATTTGTCCATGCTTGATAATATTTGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACAAGCTGATTTTCACTACAACGTTACCAACCTTGACGGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACTGCAAAACTTTTATCTTTGCTATATCTGATTGTTCTGTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC

>NC_015949|1|1|1695607-1699780|CRISPRCasFinder
GTTTTAACCCCTCTTAAGTGGAGAATCTTTTCAAC	CTCCCTTCCGATTTCTGCCAGTCCCCACACATCCA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AGCAGGATTGGCAACCGCAGCGGTAGGCCCTCTTTTAAA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GTATTGCAGGCGTAACAGAAGTTAAATCATACATAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	ACATCATTATACGCATATACCACATTACTAGCACTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CCTTCTTATCGTCTGCCTTAAGCTTTGGATAAAATC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACCAAACCCGCCACAAGAGATGAATACATTAGAGCTTTC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTTATCTTTTCAGTTTTTATATATAATAAATTGTTTTAA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AAGAAAAAATGGGTACTGAACATCCAGCATTAAAAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACCAGATAACATTGTCGATTTCCCGTTTTTTCTGGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TCAATATCATCTGCATATAACGTATTTTGCTCTAAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTGTTCCCTGCGATGTATATATGTCAATACCAAGTTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TCAATATCATCTGCATATAACGTATTTTGCTCTAAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GCAGAACAGTAACTGTATCAAGCGGCTCTATTTTGT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GAATAAAGGAGACAGAAAAGGCAGTACAGATAAGAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTAATTTGGCTTGAAGGAAGAAGAGTATTATTTATAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTATTGTTGTTTGTACAACATTAAATGCCGCTCTTAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACGTCTTTCATATCAGCACCGTCTAAAGCACCTGGCAAAATC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTTATAGAGGAGTAGACACCTACTCCTCTGTAGC
CGTTTTAATCCCTTTAAGGGAAGAATCTTCCCAAC	GAGCTGCTGCTATACAGTTCTTCGCTAAACTCTGCCTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TACATAGATTTTAAAAACATAAGTCCCGAAGTTTTTAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TGTACTCGTTAGCTTTTCAATTATACTATCCTCATTCA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTCATCATAAAGCACACAAGCAATATACTGAACATCC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CCCTACTTTGCAATACCCTTAAAAAATCTGACAGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTCATCATAAAGCACACAAGCAATATACTGAACATCC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AGAAAGAAGGTGGTTTAATATGGCACTAACTGCACAGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TAAAAGAAAAAAACGACAAATAGTAGAAGTTTGTTAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AATCGTCAAAACTTCACCGTGATAAAGTGATGAAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TAGTTATTGTTGCCTGCACAACACTAAATGCAGCTTTAAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTCCCCATAGCTGGTCTTGCAGCAATAATGTATAAGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	ATCATAACAGGTTTAAGACTATGTTTTGCAATAACTTCCTTGATGTA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTTCTTGGGTTGGTGGACTTGTATGTATACTGTTATGA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GGCAGTAGCACAGGCGGTTAAGAGTGCGATTGCAAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GCCAAGGACAGAATTTATTTACCAACCGATTTATG
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GTATTTTAGAAATGTATCAACACAAAAAAGCCAAGCTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTCAAAGAAAAACAAGCGAGCAACAAGTTGTATCAATT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	ACCGCCCAGCAAAACGTTCATCGCTCTTATCTTTTCC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GGAAAGAGTGGTTTACAGTGTCCAATCAAACGCTTC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CGAACAATGTCCTTGTAAATACAGCTACCAGATTAAAA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTGAGGTAAGAGGAGCTTCGGCTCTAACCGCAACATATGG
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TGATATGCTTTTAAAAGCTGAAAGGCAATGTTAAGTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AAAAACTAAAACCAATTAACCACAAGATTTTGGCTATTAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTGAACAATCACTCAAATAACACTTTATTTTTCCTTTC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GATTTTAATCACTATTTTAGGCACTTCGGCATAGCGTT
GTTTTAATCCCTCTTTAGGGAAGAATCTTCCCAAC	TCCGCCAGAGCCACTTGTTATTGGCTTCAATGTTCGA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AATTACAGAACGGCATATTGGAACAGGAATTAAAGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTGGTTTAAACTTCTTAGAAAGTCTGGATTATAGT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TATGAAATAATACACCCTCGCAAGCCAAAACGAAAGAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTTCAAAACGAGAAGGAAGAATATTAGAAGGATTTGACC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GTTGCAAGAAAAGTTACTGTTAGAACGTTTGTAGCTTATA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TACACCTTCAAGAATTGTCTCTTCTTTTGACATTTTAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTGCCACGGGAGTTTAGGATACTCTAACCCTTCATTAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTTATCCCTTCCCATGCACCTTTCCAATCACCTTTAATAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACTGCCAAGCGGAATTGGTATTATTGAGCTGGTAGA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTTCAAAACGAGAAGGAAGAATATTAGAAGGATTTGACC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AGCTCTTTTATTAAATTTGTCCATGCTTGATAATATTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AAGCTGATTTTCACTACAACGTTACCAACCTTGACG
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TGCAAAACTTTTATCTTTGCTATATCTGATTGTTCT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC

>NC_015949|1|1|1695607-1699780|CRT
GTTTTAACCCCTCTTAAGTGGAGAATCTTTTCAAC	CTCCCTTCCGATTTCTGCCAGTCCCCACACATCCA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AGCAGGATTGGCAACCGCAGCGGTAGGCCCTCTTTTAAA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GTATTGCAGGCGTAACAGAAGTTAAATCATACATAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	ACATCATTATACGCATATACCACATTACTAGCACTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CCTTCTTATCGTCTGCCTTAAGCTTTGGATAAAATC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACCAAACCCGCCACAAGAGATGAATACATTAGAGCTTTC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTTATCTTTTCAGTTTTTATATATAATAAATTGTTTTAA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AAGAAAAAATGGGTACTGAACATCCAGCATTAAAAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACCAGATAACATTGTCGATTTCCCGTTTTTTCTGGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TCAATATCATCTGCATATAACGTATTTTGCTCTAAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTGTTCCCTGCGATGTATATATGTCAATACCAAGTTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TCAATATCATCTGCATATAACGTATTTTGCTCTAAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GCAGAACAGTAACTGTATCAAGCGGCTCTATTTTGT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GAATAAAGGAGACAGAAAAGGCAGTACAGATAAGAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTAATTTGGCTTGAAGGAAGAAGAGTATTATTTATAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTATTGTTGTTTGTACAACATTAAATGCCGCTCTTAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACGTCTTTCATATCAGCACCGTCTAAAGCACCTGGCAAAATC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTTATAGAGGAGTAGACACCTACTCCTCTGTAGC
CGTTTTAATCCCTTTAAGGGAAGAATCTTCCCAAC	GAGCTGCTGCTATACAGTTCTTCGCTAAACTCTGCCTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TACATAGATTTTAAAAACATAAGTCCCGAAGTTTTTAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TGTACTCGTTAGCTTTTCAATTATACTATCCTCATTCA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTCATCATAAAGCACACAAGCAATATACTGAACATCC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CCCTACTTTGCAATACCCTTAAAAAATCTGACAGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTCATCATAAAGCACACAAGCAATATACTGAACATCC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AGAAAGAAGGTGGTTTAATATGGCACTAACTGCACAGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TAAAAGAAAAAAACGACAAATAGTAGAAGTTTGTTAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AATCGTCAAAACTTCACCGTGATAAAGTGATGAAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TAGTTATTGTTGCCTGCACAACACTAAATGCAGCTTTAAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTCCCCATAGCTGGTCTTGCAGCAATAATGTATAAGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	ATCATAACAGGTTTAAGACTATGTTTTGCAATAACTTCCTTGATGTA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTTCTTGGGTTGGTGGACTTGTATGTATACTGTTATGA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GGCAGTAGCACAGGCGGTTAAGAGTGCGATTGCAAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GCCAAGGACAGAATTTATTTACCAACCGATTTATG
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GTATTTTAGAAATGTATCAACACAAAAAAGCCAAGCTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTCAAAGAAAAACAAGCGAGCAACAAGTTGTATCAATT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	ACCGCCCAGCAAAACGTTCATCGCTCTTATCTTTTCC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GGAAAGAGTGGTTTACAGTGTCCAATCAAACGCTTC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CGAACAATGTCCTTGTAAATACAGCTACCAGATTAAAA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTGAGGTAAGAGGAGCTTCGGCTCTAACCGCAACATATGG
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TGATATGCTTTTAAAAGCTGAAAGGCAATGTTAAGTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AAAAACTAAAACCAATTAACCACAAGATTTTGGCTATTAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTGAACAATCACTCAAATAACACTTTATTTTTCCTTTC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GATTTTAATCACTATTTTAGGCACTTCGGCATAGCGTT
GTTTTAATCCCTCTTTAGGGAAGAATCTTCCCAAC	TCCGCCAGAGCCACTTGTTATTGGCTTCAATGTTCGA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AATTACAGAACGGCATATTGGAACAGGAATTAAAGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTGGTTTAAACTTCTTAGAAAGTCTGGATTATAGT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TATGAAATAATACACCCTCGCAAGCCAAAACGAAAGAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTTCAAAACGAGAAGGAAGAATATTAGAAGGATTTGACC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GTTGCAAGAAAAGTTACTGTTAGAACGTTTGTAGCTTATA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TACACCTTCAAGAATTGTCTCTTCTTTTGACATTTTAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTGCCACGGGAGTTTAGGATACTCTAACCCTTCATTAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTTATCCCTTCCCATGCACCTTTCCAATCACCTTTAATAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACTGCCAAGCGGAATTGGTATTATTGAGCTGGTAGA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTTCAAAACGAGAAGGAAGAATATTAGAAGGATTTGACC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AGCTCTTTTATTAAATTTGTCCATGCTTGATAATATTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AAGCTGATTTTCACTACAACGTTACCAACCTTGACG
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TGCAAAACTTTTATCTTTGCTATATCTGATTGTTCT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC

>NC_015949|1|1|1695677-1699780|PILER-CR
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AGCAGGATTGGCAACCGCAGCGGTAGGCCCTCTTTTAAA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GTATTGCAGGCGTAACAGAAGTTAAATCATACATAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	ACATCATTATACGCATATACCACATTACTAGCACTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CCTTCTTATCGTCTGCCTTAAGCTTTGGATAAAATC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACCAAACCCGCCACAAGAGATGAATACATTAGAGCTTTC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTTATCTTTTCAGTTTTTATATATAATAAATTGTTTTAA
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AAGAAAAAATGGGTACTGAACATCCAGCATTAAAAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACCAGATAACATTGTCGATTTCCCGTTTTTTCTGGC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TCAATATCATCTGCATATAACGTATTTTGCTCTAAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	CTGTTCCCTGCGATGTATATATGTCAATACCAAGTTT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TCAATATCATCTGCATATAACGTATTTTGCTCTAAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GCAGAACAGTAACTGTATCAAGCGGCTCTATTTTGT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	GAATAAAGGAGACAGAAAAGGCAGTACAGATAAGAAT
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTAATTTGGCTTGAAGGAAGAAGAGTATTATTTATAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTATTGTTGTTTGTACAACATTAAATGCCGCTCTTAC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	AACGTCTTTCATATCAGCACCGTCTAAAGCACCTGGCAAAATC
GTTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC	TTTATAGAGGAGTAGACACCTACTCCTCTGTAGCC
GTTTTAATCCCTTTAAGGGAAGAATCTTCCCAACG	AGCTGCTGCTATACAGTTCTTCGCTAAACTCTGCCTTG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	ACATAGATTTTAAAAACATAAGTCCCGAAGTTTTTACG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	GTACTCGTTAGCTTTTCAATTATACTATCCTCATTCAG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACC	TCATCATAAAGCACACAAGCAATATACTGAACATCCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACC	CCTACTTTGCAATACCCTTAAAAAATCTGACAGCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACC	TCATCATAAAGCACACAAGCAATATACTGAACATCCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACA	GAAAGAAGGTGGTTTAATATGGCACTAACTGCACAGCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	AAAAGAAAAAAACGACAAATAGTAGAAGTTTGTTATG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACA	ATCGTCAAAACTTCACCGTGATAAAGTGATGAACG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	AGTTATTGTTGCCTGCACAACACTAAATGCAGCTTTAACG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	TCCCCATAGCTGGTCTTGCAGCAATAATGTATAAGCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACA	TCATAACAGGTTTAAGACTATGTTTTGCAATAACTTCCTTGATGTAG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACC	TTCTTGGGTTGGTGGACTTGTATGTATACTGTTATGAG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACG	GCAGTAGCACAGGCGGTTAAGAGTGCGATTGCAACG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACG	CCAAGGACAGAATTTATTTACCAACCGATTTATGG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACG	TATTTTAGAAATGTATCAACACAAAAAAGCCAAGCTTG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	TCAAAGAAAAACAAGCGAGCAACAAGTTGTATCAATTG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACA	CCGCCCAGCAAAACGTTCATCGCTCTTATCTTTTCCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACG	GAAAGAGTGGTTTACAGTGTCCAATCAAACGCTTCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACC	GAACAATGTCCTTGTAAATACAGCTACCAGATTAAAAG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	TGAGGTAAGAGGAGCTTCGGCTCTAACCGCAACATATGGG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	GATATGCTTTTAAAAGCTGAAAGGCAATGTTAAGTTG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACA	AAAACTAAAACCAATTAACCACAAGATTTTGGCTATTACG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACC	TGAACAATCACTCAAATAACACTTTATTTTTCCTTTCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACG	ATTTTAATCACTATTTTAGGCACTTCGGCATAGCGTTG
TTTTAATCCCTCTTTAGGGAAGAATCTTCCCAACT	CCGCCAGAGCCACTTGTTATTGGCTTCAATGTTCGAG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACA	ATTACAGAACGGCATATTGGAACAGGAATTAAAGCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	TGGTTTAAACTTCTTAGAAAGTCTGGATTATAGTG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	ATGAAATAATACACCCTCGCAAGCCAAAACGAAAGATG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACC	TTCAAAACGAGAAGGAAGAATATTAGAAGGATTTGACCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACG	TTGCAAGAAAAGTTACTGTTAGAACGTTTGTAGCTTATAG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	ACACCTTCAAGAATTGTCTCTTCTTTTGACATTTTATG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACC	TGCCACGGGAGTTTAGGATACTCTAACCCTTCATTAATG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACC	TTATCCCTTCCCATGCACCTTTCCAATCACCTTTAATAATG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACA	ACTGCCAAGCGGAATTGGTATTATTGAGCTGGTAGAG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACC	TTCAAAACGAGAAGGAAGAATATTAGAAGGATTTGACCG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACA	GCTCTTTTATTAAATTTGTCCATGCTTGATAATATTTG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACA	AGCTGATTTTCACTACAACGTTACCAACCTTGACGG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAACT	GCAAAACTTTTATCTTTGCTATATCTGATTGTTCTG
TTTTAATCCCTCTTAAGGGAAGAATCTTCCCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_083825675.1\|1694378_1695581_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014042855.1\|1713200_1713491_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014042842.1\|1688285_1689182_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014042844.1\|1692635_1693046_-\|PIN-domain-containing-protein	unknown	unknown	gnl\|CDD\|350250
NC_015949.1\|WP_014042853.1\|1706542_1709308_-\|HD-domain-containing-protein	cas10d	cd09712_cas10d_CAS-I-D	gnl\|CDD\|187843
NC_015949.1\|WP_014042850.1\|1702810_1704859_-\|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	gnl\|CDD\|187841
NC_015949.1\|WP_014042851.1\|1704881_1705526_-\|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	gnl\|CDD\|274458
NC_015949.1\|WP_013432069.1\|1693441_1693723_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014042852.1\|1705543_1706527_-\|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl\|CDD\|375747
NC_015949.1\|WP_014042854.1\|1709422_1710397_-\|WYL-domain-containing-transcriptional-regulator	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_015949.1\|WP_014042848.1\|1701375_1701948_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768
NC_015949.1\|WP_013432073.1\|1691124_1691340_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NC_015949.1\|WP_014042840.1\|1687407_1687926_+\|ferritin	unknown	unknown	gnl\|CDD\|153113
NC_015949.1\|WP_156786161.1\|1693830_1694259_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378065
NC_015949.1\|WP_014042841.1\|1688020_1688242_+\|zinc-ribbon-domain-containing-protein	unknown	unknown	gnl\|CDD\|378250
NC_015949.1\|WP_013432070.1\|1693045_1693312_-\|AbrB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|374238
NC_015949.1\|WP_014042849.1\|1701950_1702814_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	unknown
NC_015949.1\|WP_013432072.1\|1691830_1692046_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NC_015949.1\|WP_041725793.1\|1699998_1700265_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015949.1\|WP_014042847.1\|1700385_1701372_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_014042840.1\|1687407_1687926_+\|ferritin	gnl\|CDD\|153113	cd01055, Nonheme_Ferritin, nonheme-containing ferritins. Nonheme Ferritin domain, found in archaea and bacteria, is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The ferritin protein shell is composed of 24 protein subunits arranged in 432 symmetry. Each protein subunit, a four-helix bundle with a fifth short terminal helix, contains a dinuclear ferroxidase center (H type). Unique to this group of proteins is a third metal site in the ferroxidase center. Iron storage involves the uptake of iron (II) at the protein shell, its oxidation by molecular oxygen at the ferroxidase centers, and the movement of iron (III) into the cavity for deposition as ferrihydrite.	6.84047e-76
NC_015949.1\|WP_014042844.1\|1692635_1693046_-\|PIN-domain-containing-protein	gnl\|CDD\|350250	cd18683, PIN_VapC-like, Uncharacterized subfamily of the VapC (virulence-associated protein C)-like family of the PIN domain superfamily. VapC is the PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.37445e-27
NC_015949.1\|WP_014042853.1\|1706542_1709308_-\|HD-domain-containing-protein	gnl\|CDD\|187843	cd09712, Cas10d_I-D, CRISPR/Cas system-associated protein Cas10d. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain. Fused to N-terminal HD domain; signature gene for I-D subtype; also known as Csc3 family.	1.54379e-07
NC_015949.1\|WP_014042854.1\|1709422_1710397_-\|WYL-domain-containing-transcriptional-regulator	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	9.35755e-23
NC_015949.1\|WP_014042852.1\|1705543_1706527_-\|type-I-D-CRISPR-associated-protein-Cas7/Csc2	gnl\|CDD\|375747	pfam18320, Csc2, Csc2 Crispr. The Csc2 Crispr family of proteins forms a core RNA recognition motif-like domain, flanked by three peripheral insertion domains: a lid domain, a Zinc-binding domain and a helical domain. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	3.32739e-100
NC_015949.1\|WP_014042848.1\|1701375_1701948_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	2.82318e-28
NC_015949.1\|WP_013432073.1\|1691124_1691340_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	3.28723e-07
NC_015949.1\|WP_014042851.1\|1704881_1705526_-\|type-I-D-CRISPR-associated-protein-Cas5/Csc1	gnl\|CDD\|274458	TIGR03159, cas_Csc1, CRISPR type I-D/CYANO-associated protein Csc1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family is a CRISPR-associated (Cas) family strictly associated with the Cyano subtype of CRISPR/Cas locus, found in several species of Cyanobacteria and several archaeal species. This family is designated Csc1 for CRISPR/Cas Subtype Cyano protein 1, as it is often the first gene upstream of the core cas genes, cas3-cas4-cas1-cas2.	9.95351e-25
NC_015949.1\|WP_156786161.1\|1693830_1694259_+\|hypothetical-protein	gnl\|CDD\|378065	pfam08843, AbiEii, Nucleotidyl transferase AbiEii toxin, Type IV TA system. This family was recently identified as belonging to the nucleotidyltransferase superfamily. AbiEii is the cognate toxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	8.34891e-06
NC_015949.1\|WP_014042841.1\|1688020_1688242_+\|zinc-ribbon-domain-containing-protein	gnl\|CDD\|378250	pfam09723, Zn-ribbon_8, Zinc ribbon domain. This entry represents a region of about 41 amino acids found in a number of small proteins in a wide range of bacteria. The region usually begins with the initiator Met and contains two CxxC motifs separated by 17 amino acids. One protein in this entry has been noted as a putative regulatory protein, designated FmdB. Most proteins in this entry have a C-terminal region containing highly degenerate sequence.	4.34853e-05
NC_015949.1\|WP_013432070.1\|1693045_1693312_-\|AbrB-family-transcriptional-regulator	gnl\|CDD\|374238	pfam15937, PrlF_antitoxin, prlF antitoxin for toxin YhaV_toxin. PrlF_antitoxin is a family of bacterial antitoxins that neutralizes the toxin YhaV. PrlF is labile and forms a homodimer that then binds to the YhaV toxin thereby neutralising its ribonuclease activity. Alone, it can also act as a transcription factor. The YhaV/PrlF complex binds the prlF-yhaV operon, probably regulating its expression negatively. Over-expression of PrlF leads to increased doubling time.	1.46086e-06
NC_015949.1\|WP_014042850.1\|1702810_1704859_-\|type-I-D-CRISPR-associated-helicase-Cas3'	gnl\|CDD\|187841	cd09710, Cas3_I-D, CRISPR/Cas system-associated protein Cas3; Distinct diverged subfamily of Cas3 helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Diverged DNA helicase Cas3'; signature gene for Type I and subtype I-D.	2.73618e-40
NC_015949.1\|WP_013432072.1\|1691830_1692046_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	4.08259e-07
NC_015949.1\|WP_041725793.1\|1699998_1700265_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	6.95058e-25
NC_015949.1\|WP_014042847.1\|1700385_1701372_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	6.33364e-106

>NC_015949.1|WP_083825675.1|1694378_1695581_-|hypothetical-protein
MLRRHHAKIVSWIFEIFLLLSFSFKGESVQSGNVTTAVPNKSVKVFIDGKQIPCYSIAGNLFINANHLKYFGFEIKDNKKFSFNPQVVSLSPIPAQEFSRKFTALDTPIFIDLESVATPAFYVQGEYLIFLNSIFWFCSVNKKGNDYYLKINRDLLSNYYLIRNFHVLKSSVNEYTLNQAVVKIDWKTLQLKVENVSKTLDYSGYVFGQAFNSFPKDFTFLIGTDIQNGVIASIPVLFKITEYSGTTSTQQSGMAFANQLTVEKVVNLKDFVAKLKFISSICLQNNRNVPLKVFSTNVGVTYNNIPQVAIEVVNLSLKPVDAFELNFKCYDAFNRPVKYLGFGDNVVRGLVQRQNIVPFSSSAFTWTLVDYKNTVSIKDIKFVLIHFVDGKIQNFGGSKK
>NC_015949.1|WP_156786161.1|1693830_1694259_+|hypothetical-protein
MQSYRDVVVRISPFIFIKAATPDEILADKIVAISLRKNLQGRDMWDIYYLLDQLSNKHNVHTEYELIMKKFLDYNCQPSGIAEKITLAIDKIEKRGLTELQQEMLKVLPRPAYNLFEFKFPTVVEIVRKVLTDALCKFSEGR
>NC_015949.1|WP_013432069.1|1693441_1693723_-|hypothetical-protein
MEILNQFVEYNKIPRFMFWGYEKGIDGVNYAEHEKAFVDWLYVRGLRQKWPFERICSVMDDMYLTDEDFSLDKVREYIKEIENKDLSSRLIRF
>NC_015949.1|WP_013432070.1|1693045_1693312_-|AbrB-family-transcriptional-regulator
MIQAMSKITGRGQVQLPAEIRKVIGGEIGDTVLFTMQDDGKVVIEVIKKRKLSELGGSLKSSVAFTDLEHEANSTKEIWVNKRQKGTQ
>NC_015949.1|WP_014042844.1|1692635_1693046_-|PIN-domain-containing-protein
MEKVWIDANVILRYLLQDHQEFFQKVQKIMLEAEQGKLKLLVAPITIAEVVWTLESFYKIPRKEIADVLSAFICSDGIEAEEADVVLFALKSYKESNVDFIDAYLSHHMAKLGNTKIFTFDKKHFSRLDVEILSTD
>NC_015949.1|WP_013432072.1|1691830_1692046_-|helix-turn-helix-domain-containing-protein
MEMRDIQQQEEKIERVTYTINEIAKILGISYKLAARLVHMKGFPKIQIGRRIVIPKQLFWDWLKNNPEIKI
>NC_015949.1|WP_013432073.1|1691124_1691340_-|helix-turn-helix-domain-containing-protein
MEIINLQKQREKIKRATYNIEEIAKLLGVSYKLASKLVHSKGFPKIQIGRRILVPKDLFWDWLKTNPEIKI
>NC_015949.1|WP_014042842.1|1688285_1689182_-|hypothetical-protein
MFREFFENSFYFTKKYYAYIFGLIALNMVIAAVSIIPLLILIMLFGMFLGVNFNKSFDSNFYTFSGAFAGFIVIAFILFFVWVFLLIVFIQYPFTKTMIEITRDKEIVKRPFEIYFGAIKEKNFTVGLRLIGLQFLIMIILLPIGLVVGLLGFAATKVGIAILKVILFLLCIVGVIFMFYVMIRILYSQTSLIDKGFGVMESLKFSVEITNKKVGFILLTILYGTGINVILQIPSIVVDYVSKDLTETQVLSVGIFSVVLMVVYFAILPYLTLLQYLPYNMLLKRWEDEKNQNVYVIG
>NC_015949.1|WP_014042841.1|1688020_1688242_+|zinc-ribbon-domain-containing-protein
MFYTFVCNSCQEVFEIKASISEISNGLKVSCPKCASNDVTRDYSKINIGLSAGSGAKSSSCSTCSGSKGCCGS
>NC_015949.1|WP_014042840.1|1687407_1687926_+|ferritin
MRSEKILEMLNEQLNRELFSAYFYTAMEAYFASQNLDGFAHFFMVQTKEELDHARLIFDYINKIGGRVILKELKQPKIDYSSPTEVFELALSHERFITSSIHEIAKAALEEKDLTTHNFLQWFINEQAEEEETMDKILRKLKFIKEDPSGLLFLDKELSTRVYTPPSILQEN
>NC_015949.1|WP_041725793.1|1699998_1700265_-|CRISPR-associated-endonuclease-Cas2
MYVVCYDIVDDRRRNKIANVLKSFGNRVQYSVFECFLTPTQFQRLKSRLLPLLERNDSIMCYKITPELQKDIERIGQMRYYYEEDDII
>NC_015949.1|WP_014042847.1|1700385_1701372_-|CRISPR-associated-endonuclease-Cas1
MQTLFIDTQEGQLGKKDERLIFKNYSTGEERDIKILDIHDIVVLGRATITTPAIHLLMEKKVPVHYVGLDGKYKGSIIPALGKNINLRILQYKLDSGKKLELSKLFIAGKVKNQITMLFRWQKNYGIRLEEEIEQIKKIKKKLPSAQDIAELMGYEGAISKIYFEGFKKVLPPEFCFEERNRRPPRDVVNALLSFTYTIFLTQCITGAFLSGLDPYFGYLHSNVYGRPALALDLLEEIRPVADAFVLSLLRNEQLNNENFENKFGGVYLTDEGRRTFLRKIRDRLERQSSHILMKGNITFQKTVYLQFKVLVKYLIGDIERYIPLTYK
>NC_015949.1|WP_014042848.1|1701375_1701948_-|CRISPR-associated-protein-Cas4
MENYIPISSINTYVYCPRRFYIEYFLGLREDNQYTLEGKNIQSELQFYGINGFYYKNLYVVSERFKIEGIIDIVIESSDRVCIVEKKHGKRHAWENDYFQVLAQILAFEETTNIKVNEAYIFYFESKKRQKIEVEENKITKLAEILDNMRKIAEGILKPAWEFSNKCPKCSELLNCFPYEIKQTNIFEEM
>NC_015949.1|WP_014042849.1|1701950_1702814_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MKYKKIRIVFEIELLKQLRKDEQQNSPMKIFGASFDLFLKLCAIFFDKDYVNRLHKKAAESMSFSPAYIDFKNKKLWFELNFWDDFVHIAIFDLKHRLIGYPNPSLTYSLFGISSKLIFSEYIENSPTCFEIDIQLLNQKLEKKCKTLNKYTIKFNTPFFIKLNDFNYSFPEKEIVINSLLKNCSFSDTDTLRQNLTKILPVNFEVRLEKVQYSQQSMHGCVGYITYNISNLPEDAKILLTKALIISSFRGIGAKRVQGFGNISVFLDGQDVNSFLSDYVNSSKGEF
>NC_015949.1|WP_014042850.1|1702810_1704859_-|type-I-D-CRISPR-associated-helicase-Cas3'
MEYIEICLNEYGIEQGKKELLGKKLYAHQEIIFEKIKETQESKTPRVIFNISPTGSGKTLSAYSPLLENPKYKAVGIYPTNELIADQLETLTAWGLNCFPLFAEEIDKIELSYEETSLQRSEIIERIIKAPNRQVILTNPDIIYYIAFGKYFTFEKPQRFIGNILSAFDLWVFDEFHLYDDKQKAELLAIIFSAMCVRYLDKTPVFVILSATPDFGIESIMKKMNINFEIVKAKEGDKIIQEKVNLKLIPTDLYHWQGLNKLLEIDSCIDEVYREKSSLVILDSVFQAMDYANHLREKGLDVSELHGLKRDKNGLKAHVVVGTSAIEVGIDPKEENNTYKQAVVFEARTFSQFVQRLGRIGRGNKKDRTSFVLALVPQYVYDKLKNLHQSSISRPEFFKKLESSYVKNLLFEKSISEVASLTIFNSFQKILTLVENDEEKAKIKAFFWNLTGRRFDEMKSIQQDIKEAFDSEYETFENVLFSFRNFTPTTLVVTQNDAFFMDLYDVLRRYRIKQILKTDSEIKEALERTIKDKEICTLKYKKSKKDKSCISAIEIENIYENNKRKVMVTMEIPDDMFELNYRNLYLSPIKFKVASSNNQELEIIRELNQLLKSVFFPCFIVSREDVQNLQQKTHSFLPPLFRGYPYIEPYESVEDCEDDKTIYLGRNALLMWSTFLEGGEIL
>NC_015949.1|WP_014042851.1|1704881_1705526_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1
MYIGQIRLELLDFLFFSSLEYGNYYKTSLYLHNYALCYALGLCPQRYFIQIDKTHYKEDLKNLAKQGIYTYPAKWVGDFTEFQFNSMRDDYLLSREQNSPYPIHGFIKTIAPMSFTITYIVAPEKLNLPSRIRLGKWETLTNVEVEWFKAEKVSKKDFLYQGVLNYFDLVHKPTAFNITELSLPNRLIENCFFENTILITADKIELPLCSFENI
>NC_015949.1|WP_014042852.1|1705543_1706527_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2
MIEKYLDPKVAFVDKIPDERKGYFVQVVILREAQSHLCFTTEGRILNTAILEAGYENPTKITRVVMLKRKQVAPERREGKLIRRRLIQEQNLQVAAEESKNCSLIENLCSKCPDCLLYGFAAQGGDDVARKSRVITDSAFSVQPYEQIVEELTLNAVDEITHTTKSALSSREYVKPGVVFPCVETFADVTKEEFLYLLINILYTTRYGAEASRIGTMKNKIVGIYATAGEVFTNLELTKHFYDKLSSTSFDLNNFMAAYPEIEQKIISSSPIKVYGILSGQKLEVFLNEFCKKLNEDDKYLIGIFNNVEQKVKEYLESKSQKEKKSK
>NC_015949.1|WP_014042853.1|1706542_1709308_-|HD-domain-containing-protein
MNKKIKLVSKIYKDIIEYFYKEGYYKSLAKSEEGNEQTFIEHSLKTLKYALCLFDYICELNKDLDTEENLKLLVIGALFHDINKAKNIPSEVDMTIEQLQYELSNIGYTDPYYARFVKAASIHKTREKQAATFRIKSEHSELVDIIRWADAMASVSSAEKVYEKLSKIVVDIAISYGLPKPLINLLKFNEIRLVITNYLIKAIIKLLKEQGQRIFAILPDGIIYEGSFKITMENADTILTFLKSSFEDGKVIQKIREKCFDSNKFRFTYQNFLHILDEERHIDMFRKIAEENKDRIYAKISSKYSELDLFKKAPDEIFITVSSHLFIAQQVIDTILDSKKSSKKVENRCSVVEFLMEEKLLSNQEVETVEKTIKQIEFPTGGQTDNEIVFFMYVADIVRKKIDNLFSFLDNFWNNFKATYSKLVNSNPDLANQKRLIEDDLKLYIVEDFLALSQNIFNNLNAKNKLHEVCPRCGRRVLPGTAFDKGGIIEWKYSFRLKPLSLTLKENGRLRHELNEKLLPRLCRICYIESILKNIEDISDTDYKFILYTPVDVFFNDQIIKFEEDLLSDFEFTRTTKKGDSFSYSIFNSILLDRVTPKILLQKVAELTKQVLDADEKLISSAEFNKFEVRTRKKDNLENHLRLIAAALITAVYTDLKVIVTDKSVILPSELPNKLKLDIKHPLLKKALPTSSNTYYSFEDAKNVLKMICSYYALTDITLLSVDEKDVISFIQKSTMYPLGVFGNIRFATQEERKRFKSWLSNPNIEYAVDTAISTIIEFMKGGEMMSIVQRLAETQLKFWNPSLSSSSYYFVLPFRKAVSVLKNCNVSNVEDLKAIIAGEINSLVERSENSQKVLAVKNKETLSAIEEYVSIIVDEIFQKEASAQIGKLSMLENYYSNALEYMIEKIKNENIKKAQERLKA
>NC_015949.1|WP_014042854.1|1709422_1710397_-|WYL-domain-containing-transcriptional-regulator
MAKKKSDNVLVRYERFLKYLSEGQYTQEEICNFLNISKRTLYRYIQTARKQGKNITIKNGRIALAEPCKQKEIKIELSADEKLLLSLMIEATNAYVSFFFENNPEYFRTLFNLVPERFIEVIPQPKSQLTILQRSWLLRIYYNLVEKNEFLEYEITYQKPSGEINTYKIVPFRLLFQKRSWYIVAACFEENEKLATEYRTFRINRVITLHETGRTFLPEQIAEARKRYALDRRNAWEFKGGPGTTEVIIKVHDERYWTFLTEVCWHPTQRNHPSQKTISFEVFDPNEMLPFLVQFADGIEVIAPRTLREKLFEFLRKSIERNGC
>NC_015949.1|WP_014042855.1|1713200_1713491_-|hypothetical-protein
MEGPKLIEMLQNHILEVMQQIPQCQPGSSGTSNKEIEEAAGLALNLPYQDGWLTWSILHSLINKGLVEAVEVKHGKTKRFKYRLTRGNNLVSNSNK

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Crispr_ID: NC_015949_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_2

2552404-2554751

TypeI-B

Consensus_repeat	Method
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CRISPRCasFinder
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CRT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	PILER-CR

35 spacers

cas2,cas1,cas4,cas3,cas5,cas7b,cas8b1

The CRISPR arrays of NC_015949_2

>merge|NC_015949|2|2552404-2554751|CRISPRCasFinder,CRT,PILER-CR
GTTTGTAGCCTTCCCTTTGGGGATTGAAACTTACTACGATTTTTTTCTTTCCGTCAATACAAACCAGGTTTGTAGCCTTCCCTTTGGGGATTGAAACCTATAATCAACTCTGCGCCACCTCCTTTTTTACTCAGTTTGTAGCCTTCCCTTTGGGGATTGAAACAACCCTCCCATTTTTTATTTTTTTTTCAAACCCCAGTTTGTAGCCTTCCCTTTGGGGATTGAAACTTTCACAGTACTTTCTAACAAATTCTAACATTTTCCTGTTTGTAGCCTTCCCTTTGGGGATTGAAACCGTCAAACACAAACCCTTTTGAATCTTCTAAGACCCGTTTGTAGCCTTCCCTTTGGGGATTGAAACAACCCTCCCATTTTTTATTTTTTTTCAAACCCCAGTTTGTAGCCTTCCCTTTGGGGATTGAAACAGGTCTATGATAAGGAGGGTTAAAGGATCTGTTAAGGTTTGTAGCCTTCCCTTTGGGGATTGAAACCGAATTCCATTTGTCATAACCAACCCAATAAGCATAGTTTGTAGCCTTCCCTTTGGGGATTGAAACAAGTACTCAAGCATCGTGGACAATAAGCTATTCCTTGTTTGTAGCCTTCCCTTTGGGGATTGAAACATGATAAGAGCGAATGGATAGATGAAAGGTGCTGGGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCCTTAAATACTATATTATTATTACCCTTAACCCCTGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCTATAACTCTTTTGATAACCCCTTCTCCCCTTCCTAGTTTGTAGCCTTCCCTTTGGGGATTGAAACTGATATTTGCAAGAGCATCTAACAATACTCTTGAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCACTTCCCTTCAACAATATAGGAGTCTTAAACAATGTTTGTAGCCTTCCCTTTGGGGATTGAAACCATCCAACAAAATTCCCTCAATAACTGTCCTGAAAGGTTTGTAGCCTTCCCTTTGGGGATTGAAACAACCGTATCCGCATGTCTTCTGTAATGTCGTTTCTGGTTTGTAGCCTTCCCTTTGGGGATTGAAACTAATGTCTAACTCCTGCTTTATAACTCCATCTCGCAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACGAAAATATTGCGCTAAATAGTTTCTTAGCTCTGTAGTTTGTAGCCTTCCCTTTGGGGATTGAAACCGGACAAATGGCTTGAGGACTGGGAACGCTATGTGGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCTTGCAAACACAACGGCAGGGCGTGATTTATATACATTGTTTGTAGCCTTCCCTTTGGGGATTGAAACAAACCAAGGCAAGGGAAAAGGTTAAGCCCTAATCCGTTTGTAGCCTTCCCTTTGGGGATTGAAACTTAGATGTCCTTGCAAATATCATAACATGTTCACTGGTTTGTAGCCTTCCCTTTGGGGATTGAAACGTATAATATAGCTTCTGAACTTCTAACTTCTGTGCAACGTTTGTAGCCTTCCCTTTGGGGATTGAAACTATATACAACATGCAAAACCTTCACCTATAGGCATTGTTTGTAGCCTTCCCTTTGGGGATTGAAACAATATCCTGCTTTTTTCCCATACACATTCCATTATGGTTTGTAGCCTTCCCTTTGGGGATTGAAACGGATAAAATACAAAAAGGCGAGATTATTGCATGTGAGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCTCATCAGCTAATTCCCTCAAAACAACATCAAGGCGTTTGTAGCCTTCCCTTTGGGGATTGAAACTTGTGAAGAACCTTTCTAAATATTAACTTTACCATTGTTTGTAGCCTCCCCTTTGGGGATTGAAACTTTCTGATAGGTTAGGCCATTCGCAAATCTCAAGGTTTGTAGCCTTCCCTTTGGGGATTGAAACAATACAAGTATATTGCGTGGCTTGCCATAAGGCTTGTTTGTAGCCTTCCCTTTGGGGATTGAAACTGGAAGCATATTTAAAGAAAAAGCGTTCACTACAAAGTTTGTAGCCTCCCCTTTGGGGATTGAAACCATAAATTCGTTTACTTCTTCTATTTCGTAATGCCCAGTTTGTAGCCTCCCCTTTGGGGATTGAAACAGAAATTCACTATCAAGACGACGTTTGCTGTTCGGGTTTGTAGCCTCCCCTTTGGGGATTGAAACTTTCTGATAGGTTAGGCCATTCGCAAATCTCAAGGTTTGTAGCCTTCCCTTTGGGGATTGAGGTGGGAGGGGGGGTTTGTAGCCTCCCAGTTGGGGATTGAGGAGAGAGAGAGTTTGTAGCCTGTCCTTTGGAGATTGAGAA

>NC_015949|2|2|2552404-2554751|CRISPRCasFinder
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTACTACGATTTTTTTCTTTCCGTCAATACAAACCAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTATAATCAACTCTGCGCCACCTCCTTTTTTACTCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACCCTCCCATTTTTTATTTTTTTTTCAAACCCCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTTCACAGTACTTTCTAACAAATTCTAACATTTTCCT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CGTCAAACACAAACCCTTTTGAATCTTCTAAGACCC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACCCTCCCATTTTTTATTTTTTTTCAAACCCCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGGTCTATGATAAGGAGGGTTAAAGGATCTGTTAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CGAATTCCATTTGTCATAACCAACCCAATAAGCATA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAGTACTCAAGCATCGTGGACAATAAGCTATTCCTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATGATAAGAGCGAATGGATAGATGAAAGGTGCTGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCCTTAAATACTATATTATTATTACCCTTAACCCCT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTATAACTCTTTTGATAACCCCTTCTCCCCTTCCTA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGATATTTGCAAGAGCATCTAACAATACTCTTGAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCACTTCCCTTCAACAATATAGGAGTCTTAAACAAT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CATCCAACAAAATTCCCTCAATAACTGTCCTGAAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACCGTATCCGCATGTCTTCTGTAATGTCGTTTCTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TAATGTCTAACTCCTGCTTTATAACTCCATCTCGCAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GAAAATATTGCGCTAAATAGTTTCTTAGCTCTGTA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CGGACAAATGGCTTGAGGACTGGGAACGCTATGTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTTGCAAACACAACGGCAGGGCGTGATTTATATACATT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAACCAAGGCAAGGGAAAAGGTTAAGCCCTAATCC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTAGATGTCCTTGCAAATATCATAACATGTTCACTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GTATAATATAGCTTCTGAACTTCTAACTTCTGTGCAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TATATACAACATGCAAAACCTTCACCTATAGGCATT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATATCCTGCTTTTTTCCCATACACATTCCATTATG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GGATAAAATACAAAAAGGCGAGATTATTGCATGTGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTCATCAGCTAATTCCCTCAAAACAACATCAAGGC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTGTGAAGAACCTTTCTAAATATTAACTTTACCATT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTTCTGATAGGTTAGGCCATTCGCAAATCTCAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATACAAGTATATTGCGTGGCTTGCCATAAGGCTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGGAAGCATATTTAAAGAAAAAGCGTTCACTACAAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CATAAATTCGTTTACTTCTTCTATTTCGTAATGCCCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AGAAATTCACTATCAAGACGACGTTTGCTGTTCGG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTTCTGATAGGTTAGGCCATTCGCAAATCTCAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAGGT	GGGAGGGGGGGTTTGTAGCCTCCCAGTTGGGGATTGAGGAGAGAGAGA
GTTTGTAGCCTGTCCTTTGGAGATTGAGAA

>NC_015949|2|2|2552404-2554751|CRT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTACTACGATTTTTTTCTTTCCGTCAATACAAACCAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTATAATCAACTCTGCGCCACCTCCTTTTTTACTCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACCCTCCCATTTTTTATTTTTTTTTCAAACCCCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTTCACAGTACTTTCTAACAAATTCTAACATTTTCCT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CGTCAAACACAAACCCTTTTGAATCTTCTAAGACCC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACCCTCCCATTTTTTATTTTTTTTCAAACCCCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGGTCTATGATAAGGAGGGTTAAAGGATCTGTTAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CGAATTCCATTTGTCATAACCAACCCAATAAGCATA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAGTACTCAAGCATCGTGGACAATAAGCTATTCCTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATGATAAGAGCGAATGGATAGATGAAAGGTGCTGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCCTTAAATACTATATTATTATTACCCTTAACCCCT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTATAACTCTTTTGATAACCCCTTCTCCCCTTCCTA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGATATTTGCAAGAGCATCTAACAATACTCTTGAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCACTTCCCTTCAACAATATAGGAGTCTTAAACAAT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CATCCAACAAAATTCCCTCAATAACTGTCCTGAAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACCGTATCCGCATGTCTTCTGTAATGTCGTTTCTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TAATGTCTAACTCCTGCTTTATAACTCCATCTCGCAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GAAAATATTGCGCTAAATAGTTTCTTAGCTCTGTA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CGGACAAATGGCTTGAGGACTGGGAACGCTATGTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTTGCAAACACAACGGCAGGGCGTGATTTATATACATT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAACCAAGGCAAGGGAAAAGGTTAAGCCCTAATCC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTAGATGTCCTTGCAAATATCATAACATGTTCACTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GTATAATATAGCTTCTGAACTTCTAACTTCTGTGCAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TATATACAACATGCAAAACCTTCACCTATAGGCATT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATATCCTGCTTTTTTCCCATACACATTCCATTATG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GGATAAAATACAAAAAGGCGAGATTATTGCATGTGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTCATCAGCTAATTCCCTCAAAACAACATCAAGGC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTGTGAAGAACCTTTCTAAATATTAACTTTACCATT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTTCTGATAGGTTAGGCCATTCGCAAATCTCAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATACAAGTATATTGCGTGGCTTGCCATAAGGCTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGGAAGCATATTTAAAGAAAAAGCGTTCACTACAAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CATAAATTCGTTTACTTCTTCTATTTCGTAATGCCCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AGAAATTCACTATCAAGACGACGTTTGCTGTTCGG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTTCTGATAGGTTAGGCCATTCGCAAATCTCAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAGGT	GGGAGGGGGGGTTTGTAGCCTCCCAGTTGGGGATTGAGGAGAGAGAGA
GTTTGTAGCCTGTCCTTTGGAGATTGAGAA

>NC_015949|2|2|2552669-2554609|PILER-CR
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CGTCAAACACAAACCCTTTTGAATCTTCTAAGACCC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACCCTCCCATTTTTTATTTTTTTTCAAACCCCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGGTCTATGATAAGGAGGGTTAAAGGATCTGTTAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CGAATTCCATTTGTCATAACCAACCCAATAAGCATA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAGTACTCAAGCATCGTGGACAATAAGCTATTCCTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATGATAAGAGCGAATGGATAGATGAAAGGTGCTGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCCTTAAATACTATATTATTATTACCCTTAACCCCT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTATAACTCTTTTGATAACCCCTTCTCCCCTTCCTA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGATATTTGCAAGAGCATCTAACAATACTCTTGAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCACTTCCCTTCAACAATATAGGAGTCTTAAACAAT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CATCCAACAAAATTCCCTCAATAACTGTCCTGAAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACCGTATCCGCATGTCTTCTGTAATGTCGTTTCTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TAATGTCTAACTCCTGCTTTATAACTCCATCTCGCAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GAAAATATTGCGCTAAATAGTTTCTTAGCTCTGTA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CGGACAAATGGCTTGAGGACTGGGAACGCTATGTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTTGCAAACACAACGGCAGGGCGTGATTTATATACATT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAACCAAGGCAAGGGAAAAGGTTAAGCCCTAATCC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTAGATGTCCTTGCAAATATCATAACATGTTCACTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GTATAATATAGCTTCTGAACTTCTAACTTCTGTGCAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TATATACAACATGCAAAACCTTCACCTATAGGCATT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATATCCTGCTTTTTTCCCATACACATTCCATTATG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GGATAAAATACAAAAAGGCGAGATTATTGCATGTGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTCATCAGCTAATTCCCTCAAAACAACATCAAGGC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTGTGAAGAACCTTTCTAAATATTAACTTTACCATT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTTCTGATAGGTTAGGCCATTCGCAAATCTCAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATACAAGTATATTGCGTGGCTTGCCATAAGGCTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGGAAGCATATTTAAAGAAAAAGCGTTCACTACAAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CATAAATTCGTTTACTTCTTCTATTTCGTAATGCCCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AGAAATTCACTATCAAGACGACGTTTGCTGTTCGG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_014043365.1\|2550738_2551974_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293879
NC_015949.1\|WP_013433665.1\|2545593_2547372_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|224157
NC_015949.1\|WP_014043366.1\|2554908_2555907_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|368098
NC_015949.1\|WP_014043364.1\|2549024_2550722_-\|Hsp70-family-protein	unknown	unknown	gnl\|CDD\|212667
NC_015949.1\|WP_014043359.1\|2538340_2539042_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236795
NC_015949.1\|WP_014043358.1\|2536880_2538296_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NC_015949.1\|WP_014043367.1\|2556165_2557158_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_015949.1\|WP_014043360.1\|2539136_2540192_-\|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE	unknown	unknown	gnl\|CDD\|180835
NC_015949.1\|WP_014043362.1\|2542938_2545470_-\|endoglucanase	unknown	unknown	gnl\|CDD\|376383
NC_015949.1\|WP_014043363.1\|2547395_2549015_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043371.1\|2561013_2561898_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_015949.1\|WP_014043376.1\|2571683_2572103_+\|YgiT-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|240606
NC_015949.1\|WP_014043368.1\|2557199_2557697_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_015949.1\|WP_014043374.1\|2567716_2568892_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043370.1\|2560239_2560992_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09692_cas5_CAS-I-B	gnl\|CDD\|187823
NC_015949.1\|WP_014043369.1\|2557726_2560150_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_015949.1\|WP_014043372.1\|2561919_2563983_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_015949.1\|WP_013404366.1\|2555896_2556160_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015949.1\|WP_014043361.1\|2540376_2542830_+\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NC_015949.1\|WP_041725835.1\|2535993_2536644_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_014043365.1\|2550738_2551974_-\|hypothetical-protein	gnl\|CDD\|293879	cd16269, GBP_C, Guanylate-binding protein, C-terminal domain. Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.	0.00457754
NC_015949.1\|WP_013433665.1\|2545593_2547372_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|224157	COG1236, YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis].	2.5029e-39
NC_015949.1\|WP_014043366.1\|2554908_2555907_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|368098	pfam04754, Transposase_31, Putative transposase, YhgA-like. This family of putative transposases includes the YhgA sequence from Escherichia coli and several prokaryotic homologs.	8.38843e-18
NC_015949.1\|WP_014043364.1\|2549024_2550722_-\|Hsp70-family-protein	gnl\|CDD\|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	1.89799e-88
NC_015949.1\|WP_014043359.1\|2538340_2539042_-\|hypothetical-protein	gnl\|CDD\|236795	PRK10920, PRK10920, putative uroporphyrinogen III C-methyltransferase; Provisional.	0.00134295
NC_015949.1\|WP_014043358.1\|2536880_2538296_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.7738e-49
NC_015949.1\|WP_014043367.1\|2556165_2557158_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	9.9555e-159
NC_015949.1\|WP_014043360.1\|2539136_2540192_-\|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE	gnl\|CDD\|180835	PRK07094, PRK07094, biotin synthase; Provisional.	0
NC_015949.1\|WP_014043362.1\|2542938_2545470_-\|endoglucanase	gnl\|CDD\|376383	pfam00759, Glyco_hydro_9, Glycosyl hydrolase family 9.	1.38511e-154
NC_015949.1\|WP_014043369.1\|2557726_2560150_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.9376e-46
NC_015949.1\|WP_014043371.1\|2561013_2561898_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	3.0147e-70
NC_015949.1\|WP_014043376.1\|2571683_2572103_+\|YgiT-type-zinc-finger-protein	gnl\|CDD\|240606	cd12870, MqsA, antitoxin MqsA for MqsR toxin. This family includes domains similar to the antitoxin MqsA that binds motility quorum-sensing regulator MqsR, a toxin that is highly upregulated in persisters (dormant cells found in biofilms that are a source of antibiotic resistance), thus forming a unique toxin:antitoxin (TA) pair. MqsA neutralizes MsqR toxicity. It binds its own promoter as well as those of genes important for E. coli physiology, such as mcbR and spy. It also binds zinc and has been shown to coordinate DNA via its C-terminal domain. This family also includes the B. subtilis YokU protein, which is functionally uncharacterized.	3.86959e-07
NC_015949.1\|WP_014043368.1\|2557199_2557697_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.42795e-72
NC_015949.1\|WP_014043370.1\|2560239_2560992_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187823	cd09692, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.24356e-26
NC_015949.1\|WP_014043372.1\|2561919_2563983_-\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	7.76302e-142
NC_015949.1\|WP_013404366.1\|2555896_2556160_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.57908e-32
NC_015949.1\|WP_014043361.1\|2540376_2542830_+\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0

>NC_015949.1|WP_014043365.1|2550738_2551974_-|hypothetical-protein
MHSAEHKEENTLTKRPDFPKDATPKQNTSYKLLLRKELKNVQNFGKFFFELDVLTIAGVSRCLKDGNNFESVKRFVKERLERYQFDANEIHLIIDYLNADNFSFKLMVNEGIERIEKDRFIIEAFVKCYIARYFANRLFEGKKGLMKEIEKDFSEMCGQENLYFFGELKKWIISYDIWPKTAQQYAEIASSFKDEIEDVYSKVFSEVQKRRLIKIGKKKDHQEESQNIAEKAVKSQAEAVAGTRENEEFRKLKEKLENYELMVNMLQEQIEELREINSELQKEREMLLQERQQLPEKILIKLFNDLNSPQFGNLLDKIYVYANDLEPVDSSTAQEIFTNIISVLSLYNIVGHLSKEEYKSTISIKKEEIGSIYRCDRPAQSDKQVYEAQILYPKWTYNQKTVANKFVRIKS
>NC_015949.1|WP_014043364.1|2549024_2550722_-|Hsp70-family-protein
MHIGIDLGTTNTVVSYAKRKARGGVEPQVMRITQLDEYNSSIQEEILPSVLFLDFDGNIVIGKKAKHMKQYHPGRTISNSKRYMGTSMVFRIEDRAFTPVDVAANILKVCKRTIELNLGGKPVQQVTITVPASFNTDQIRDTRNAALKAGFDPDRIRIIPEPTAAFIDFINEQSELVEEDRLVDISTPKRVLVFDLGGGTCDIVVMDVVQSGNCLKVEEKAVGRYSELGGIDFDLAATRYLLQKFFVDNKIKEGDVEPVEQSQMVNKLMAFCEKAKEFFSNQMMLNPEIESTNPSFKMNIPEFWRGKSQLFSITLKEYNTATRDLYHSSGIKAKTIEDYERCKNIVDPIYETLERYEIDKNSIDYIFATGGMSLYYKVVQRLKELFPKSQVIKASNPLEAVSRGAAIFSFYEVEIKRQNEKASISKPTIKEPSSAEMEIVTKTVLAEAIMIDVEEGLPREIISKNQPVPYKGVIRDSFRVTSPSGIKIDIYAGEDPYDCKMRIQKSFTGNFRSPVTPGTPLDIEYEIDENKYLKLRVVVKDNMNPPIDLDVDSDVKTVGLEKVKE
>NC_015949.1|WP_014043363.1|2547395_2549015_-|hypothetical-protein
MDKVFKDFKEINIDLFENIFIPEMDSIEKSIVGTSNINYVSNRLFMWMFSKEDVKEFESIFGLLRQPKYGYVRSEFKRKLISQCNKMLKEGICPIEPMLYASKTVNRIISNDVEDHEDISDVICEVEKYDRNMVVKTLEHIITRWSWYPQLKIALLAAGKVSDDDLIQMAYNKFSDNKYLNYLKPELLKMLVYSKKASFVPQMVSILSTLERDSTSDRAIANFFRENFDKYVGREGVTELNIYYEMNYSFIKDFAKSIIQAVLKDCPLPLQDGPDKKFTYFKQLCIAYSKQKQNEKLRKEILKNLFDSSYSAFSSMVYCLRYTKDKALATYLEDAVLRRKDAKIGDYKNAILTLGFLGADNHDFVMELSKRDKDLKYAMYGFFIVQGSETYCTLMADELIFCKDLSELGSIHRVLREVINVSPKLRSIIKEKLKAALLDDSKEVRKIALLNIQPYWRHIIDKDILNFLFEQIGYPDKPIKFSIEEQSIVLKIAKDVINNFGRNIYKYLDYVRRRNDFDPNIKQLATRILLNDFEPAPPQ
>NC_015949.1|WP_013433665.1|2545593_2547372_-|MBL-fold-metallo-hydrolase
MLLDSHEKYIALKENNVDVQKELCRNLYRAGNYLTCFLLSSKLVEMGEEREKIVQLSSLARLGYIDLVFHAFESDKEKIERHILAFADEDLDIAVDLLFSVDTIDECESELAKRIENASKSYENCRLWLDLRRLSEKFRSKNYIVCNNISCILEKIEKTEDSFIKTRASYRLYDLGIEKCREYLNEKYLKHEEKQKTGFNTSDDIYCFEIPENIAKKIWYFNYQDHHVHFFTYPDHNIHFLRFENEILVLDCGSNPKEFSIVDIEGFLTQKGYSTNMIKAVLISHAHYDHYSCLQYLPHSIPLYATKETIDLIFIVNREHLESKKINLVKCNEEFEVGKFRITPFSNGHILGSVGFDIQFGNKRLIYTGDFSLHNQMTAEGMNLQDILKRGKVNYLVSEHTYGQKDFAIKYEDAAKCLAYAVDFLVTLGIKVFIPAFSIGRAQEVIEIIFAFCRTKPMVVVDGLAKDISLYYSARSGKNFFHNVILGSSKDIENNVQGADVIVASSGMLQSHSTAVKYLQILKDTKFGFIKTGYIEDQHYIHEMVKVMMNSDVYYFDIPLSAHSNYFELLQTFRVLEPEKIILVHGQGIKGL
>NC_015949.1|WP_014043362.1|2542938_2545470_-|endoglucanase
MKTARLLVCFVLVCFILTTTILLDNNKGEAAMYNYGEALQKAIMFYEFQMSGKLPKWIRNNWRGDSGLNDGKDNKIDLTGGWYDAGDHVKFNLPMSYTATMLAWAVYEYKDAFVKSGQLQHILNQIEWVNDYFVKCHPEKYVYYYQVGDGGKDHAWWGPAEVMPMERPSYKVTKTNPGSTVVAETAAALAAGSIVIKQRNSKKARIYLKHAKELYDFAAETKSDAGYTAANGYYNSWSGFWDELSWAAVWLYLATGDKYYLSEAKKYVSNWPKIAGSNTIDYRWAHCWDDVHYGAALLLAKITDENTYKQIVEKHLDYWTIGYQGQRIKYTPKGLAWLDQWGSLRYATTTAFLAFVYSDWKGCPSSKKKVYRKFGEGQVNYALGSSGRSFVVGFGKNPPKRPHHRTAHGSWANSQSEPPYHRHILYGALVGGPGLDDSYSDDVGNYVNNEVACDYNAGFVGALAKMYLLYGGKPIPNFKAIEKPSNDEFFVEAGINASGSNFVEIKAIVYNQSGWPARVTNNLKFRYYINLSEIVSQGYKPSQISLNTNYNQGAKVSGPYVVDSKKHLYYILIDFSGTSVYPGGQDKYKKEVQFRIAAPQNARWDNSNDYSFKGLDKTGGGQVIKTKYIPLYDGKKLVWGIEPNTKNLTLRTSQIPANGDADKKSKTILSKNTSSAKTSSKQNKEVKNVVKVLYKNMEINKTSNSIRLYLKIINNSQETIDLSKVKIRYWYTADDGVMKQSAVCDWAQIGAVNVTFRFVRLRKAVAKADHYLEIGFTNNAGKLQPGKDSGDIQLRFNKSNWGNYDQSNDWSWVQSMTSYGENKKITLYIDGKLVWGQEPTKDT
>NC_015949.1|WP_014043361.1|2540376_2542830_+|PBP1A-family-penicillin-binding-protein
MQSKNKKVKKQTPFRLFLKSFVRTLLALLIASMAVLIGAGFGMVTGYIKAIPPNALDIITSSANSQTTIVYDQSGNEIARLHGNENRIRVPYSKIPKNLINAFVAIEDERFWQHNGIDIKRIFGAIFKNIKTGSLSEGASTITQQLVRNKLLTFEKSFKRKIQEQYLAIQLEKRWTKEQILEEYLNTINLGSGAYGVGAAAYTYFGKDASQLTLAECALIAGITQNPSYYNPYVFPDHAKKKQEIVLKKMLELGYITEQEYLEAKNQPLVYVKKDISAQNAYKHPYFVDSVIDEAVEILSDKKRISEDEAENLIYGGGLKIYTTMDEAIQSTMEDVFSDPSIMPKIRHYDASGVPQPQAAAVLIDFRTGAVKGIMGGRGNLKGVRLLNRATMSVRQPGSSIKPIADYALALENGYTAATVIDDVPFSIGGYTPRNWYKSNVVSGKRGYKGFMTVREALQWSANVPAVKVAYNLGIQNVYRNLKRFGFTTLAPQDMNSLSIAIGGFTYGVKPIELTAAFAAVANSGVYIKPYFITKIEDKNGITIFERTPYKRRVMDEKNAYILTNMLQSVVTARITVGVRFSYPVAGKTGTTDDSKDRWFVGYTPNYALGVWVGEDKPVALNYLTGTNPALKIFKGIMDKVVSKKGVSPEFLRPAGIVERYICKESGKLATSLCKQDPRGSQVIKEIFAEGTEPTEYCDRHVKLKVCTESKKLATQYCPTIIEKVFIKRDNPIWPSKNSSVVPPDDYMYQAPTEYCDIHKAPQEVVVPQEGNTSQNEPSGFQKLKPPSTRQSNQQASEKNIPFDHSTTENNTYSIQQ
>NC_015949.1|WP_014043360.1|2539136_2540192_-|[FeFe]-hydrogenase-H-cluster-radical-SAM-maturase-HydE
MKVRDILEKARHENILTKDEIKLLLMAEGEDKDLLFKTADRVRKEHVGDEVFLRGLIEFSSYCKNDCFYCGLRRSNNQAQRYRMQEDEIVEVAKRAYQMGYRTVVLQSGEDMYYNKDMLCSIIKKIKSSVDVAITLSIGERSYDEYKAFKDAGADRFLMRFETSNRQLYEKYHPGMSFENRIECLKWIKSLGYELGTGFLIGLPGQTIDDLAQDILLVKELDADMIGIGPFIPHPQTPLKDAKEGSVDLTLKSIAILRLLIPDANIPATTALGTLDPLGRQKGLMCGANIVMPNVNDLKYKLKYELYPGKICINEDATKCRGCIESIIISLGRKVGQGKGQSRHYKRAAAS
>NC_015949.1|WP_014043359.1|2538340_2539042_-|hypothetical-protein
MSMKRGKGNTKKVWLVVLIVAICALGILAGYYMAGYLAKKPAAVNQPVQTNQPSQQLQEENDQNATSQAQKEQATNLQPSEQQQQDTTISSEVYKAFARFDGGIDAHTIQLSLLNTEFDYKEFEIDEKVKKGVELSEGEIVEIEFEKPQDGGNPRIVSLKKPDKVTLKGKFVGLADNNFAEFVFDQKHVVLQISNVADKVSYLDENTDVEVTFKTNPQNPQSNPVVKDIKVLK
>NC_015949.1|WP_014043358.1|2536880_2538296_+|MFS-transporter
MHVQEDRKINKNILIATTLSSFLVPFMSSAVNIAAPDIAKSFNLNAEELNLVISIFLIFSAAFILPMGKLSDTFDRTKIFKTGLLLFTLSTLMCALSNTVEILFVFRALQGFFSAFTFVTSMAILIENHSPQIRGRLLGINTAVVYLGTSLGPFLGGVLVKLWGYRSIFLFGFAIGLVGSFVSLFLLHKEVKNTRQAKLLDSLKSLDKIGTILSMTGLFLLMYGASTFELGNTSKILFFAGLILMIIFVVAEAKLQNPILDVKLFVKIPQFGFSNLAALINYSCTFSASYLLSLYLQLVKALPSQLAGSVLIVQPLSQVITSLISGRASEKIEPRKLATAGMVLTTIGLFVFSLFSSKTSLVLAVANLLLMGIGFGLFSSPNTNVVMSCVPKSLYGTASSTISVMRVIGQAFSMAIVSFVSIMFLKGVKLSHENYLLILKSMKTSFLVFASLSILGIVASYKRGNIYGRNS
>NC_015949.1|WP_041725835.1|2535993_2536644_-|hypothetical-protein
MKVAWSATHQEFLLTDGYYFSGLYKELCKRKIEIEEVDHFDRLFEYDVIVFNYPENPFSDDEKEKIREALVQKGKRIIFTAHFKNKDGVSEICNSITREYGIDILPEGIKDEIHHLEDDLFIITTDEVKLYREGVKEVVFPYSAPLEVREETEVVLRARETSLTDSGKKSPVLIAQRKFESGGKLIVCGSCIFWDNFSLFRLDNLQFVVNMFEGVE
>NC_015949.1|WP_014043366.1|2554908_2555907_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MCEKLPPKEHDTTFKFLFADKEEILLLVKDILHYTWADNIEEDTIELVKTNYVTQQFSQVEADVVAKAKLKDKEVYFYILIENQSKVKREMQQKILKYMISLWAEEIRKGVQILPAIIPIVVYNGIGERWNVSTDLMEAFDVFKDDVFRYRVVDIIELDVKKLLEREEDVLTPIVFYLEQAREDRSELIGRLLEVEKNLKKLSKKNVDRFLEWSYHIIRPRLAEDQKSEFDRIAKRVKQEGVEAMGEFISNVARLLDEAKTKDFLAGKLEGKLEGKIEGKIEGKLEGKLEATIEFAKRLIQKGFSDEEVAELTELQIEKVKELRKSFKNTMS
>NC_015949.1|WP_013404366.1|2555896_2556160_-|CRISPR-associated-endonuclease-Cas2
MFVILVYDVNEKRVAKALKKCRQYLTWVQNSVFEGNISEGTLRRLILELERILDLSEDSVIIYKFQNTWYSERQIIGIEKNPVDFMT
>NC_015949.1|WP_014043367.1|2556165_2557158_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKDLYVFNSGFLRRKDNTIMFETDEGKKYFPVEEIESVFIFGEVDINKRFLEFMTEKNICVHFFNRYEYYVGTYYPREHYNSGIVILKQVEFYNDYNKRMTIARSIVEGAVLNMLVVLRYYNSRGNILKDEIETIERMRHNINSCDDVNTLMALEGNIREIYYRCFNKILDDENFTFVRRSKNPPLDRINALISFGNSLLYATTLGEIYQTQLDPRIGYLHSTNQRKFSLNLDISEIFKPIIVDRVIFSLVNKKVLSEKHFERELNGIILNDQGKKLFVSEYNQKLYSTITHPKLNCQVSYKRLIRMEAYKLQKLFLENIEYKPFVARW
>NC_015949.1|WP_014043368.1|2557199_2557697_-|CRISPR-associated-protein-Cas4
MDVYMTGVYIWYYNICKRQVWLMAHGVLPDENDDNIVLGRFLHEYYYKKDQKEIKFGNAVFDILYQDKDEIVIGETKKSSRFKEASRYQLLFYIKLLKEAGISAKGVLFYPEERKKEEVELTVEDEEKLQKMIAEIETIIEKDSPPPAAYCRYCPKCAYREYCFA
>NC_015949.1|WP_014043369.1|2557726_2560150_-|CRISPR-associated-helicase/endonuclease-Cas3
MEYYSHKNPDKLLYDHLLEVYHYAMEANVELKSWEKEALQVICLCHDFGKFTTFFQSHLNGVLNKYSQHGFISALFGVFCWMQKKGLWLQQMKNQISEDEVVSLLIYACILHHHGDVKDISKNLPEKFAGDFKADINLVQKIDDAYVQIEDLRCNAEDIKPLLEKIGLGSEFEKFLAQQRGFIEDILRYLKRIEYGIRFIGVMPQALKDGTELYFIQQKLYSLLIWADKMSAANYKVLSPCYASSDRLIVARNKVIRPTADKNLQRIRQSVFEAVLSNIEKNKEKDIFSITTPTGTGKTLAGVFAAVKLKELLKKSGRIIYALPFTSIIDQNYDVVKNLFEAIEDFEKNRDRYLLKHHHLTDGEYRGKEEALKEITDEITVYEKVASECFIENWTSGFVVTTFVQLLETLISNRNRMLKKFHAFYDSILILDEIQAIEVDLLPLVEEVLRKLSKLFKCKIILMTATKPLIFEDACELAGFCDYSIFNRTKLVYHHSDLKVAEFVDFFLEQVYEDEKSFLIVANTINQSLQIYNGIKNNLKDKEVIYLSANLVPRDRKEVIKKIEEALESGRKPIVVSTQVIEAGVDIDFDCVIRDIAPIDSIIQCAGRCNRHNQKSQGKVLVVNIKDDSGRSFAKRVYGNTAIEISNMLLLQHPEVEEKDYGMLIDNYFRMVKENKSFKKSEEFLRSIRLLKFDSILEKEELTISRFSLIQQRGGYVSVVIRSNEEIEDAYQSYINSFSIKDYYKRREIYLELKNILFEHTISVPSKYVQILAEEKGILSLPPTSCERYYNPETGFVYDPNDNVIFA
>NC_015949.1|WP_014043370.1|2560239_2560992_-|type-I-B-CRISPR-associated-protein-Cas5
MKFLVFDLKGKFAHFRKFYTNSSSLSYLVPPRTVVEGVVAAILGFERDSYYEELSAENLLIAVQKIERTYKIVQTVNYIKATSVNELKNPNTHTQVPLELLAGYNGFVGFRVFVMPRDEKMYSQLKSKLESGRAEFPIYFGSAPFAAKTEFVGEFEAYRWEDSSARILTVLDTGLMKSLNLSLESSAGLALMKDRMPCDFDKDRFATKVKTYINDENLNPIWVDLDSSAQDKVYFIKEFSSDKELCISLM
>NC_015949.1|WP_014043371.1|2561013_2561898_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MEKKIIDKNSEILFTYDAKLCNPNGDPDEENRPRMDWEKEINLVSDLRVKRYIRDYLDDKGIPIYVRKIDGKSVKPEEVIKSVGEDIDELETFIDIRLFGATIPIKGETRTYIGPVQFNWGYSLNKVELLEASITSHFASREKNQQGAIGKDYRVKYSFIAFSGIVSAKRAKITRLTEDDVRFLDRAMKEAIPLQATRSKIGQYPRLYMRVEYVDDKTLLGDLRDYIRLIEVVEKPRKIEDVQLDITSLVEFLEKNKDEISKIYYFKHPDLCLVCGGNAVDFKDAFGTFELEEV
>NC_015949.1|WP_014043372.1|2561919_2563983_-|TIGR02556-family-CRISPR-associated-protein
MIEEIVEIGDILIGVSSGNEAYLSALIEEIEVPSGNEKNFVAKINFSTKEKIITIDCAEEVKDSTAKDYVYVGSAEGSNSPQWFASTKSFAYFLTETIPNLAERSIPVVSDICKKILDDYFVNIKEYLLSSAELTEEEKMLLNQRIEKKYMYFLNTDHVMVNDNKKLTERPISQIYKELIRKGKSTDKVFKQLRDAFTKECTDGLKKLTELKPQQIGLYVLCVDGKPLTSYPEYVEAVVAYKRQVKKGAEKTGEKQKEGNICYICLGTDGLSFEGLKKPKFKYFTTNQNIFASYLDQKNYAKNITVCEKCLSKLVAGDIFLRNKLKTQFGSFDVYVLPTFVYTSAKLTKNYLEDLTLNITNSLNTAWNYNRLEKLRDDISNFLSFFDQNHYFLLNLIFYREAQAGTKIMKFIPDINPSIFDKIYNAASKVFSQYIDIIGNDPSFRISLESIYYSVPIRLKNRNESTEAQRLLNIYDAIFSGKRIARDFLIENFIKAVGVVVYGKEGYNLSKFIGNDIALMVIRMVFVMKFLEFLDCLEVERGMDVSQLNLSDDLKSYIQQMNYDEPKTALFLLGVLIGEIGAKQYLATKDRQDDSAGHKPILNKINYNGIDRPKLIRLCSDVHNKLRQEKLLPYTEMIFAEMKRLLDKHIDSWKLDKYETLFYILSGYAYKTQKVILNASNSQETSN
>NC_015949.1|WP_014043374.1|2567716_2568892_-|hypothetical-protein
MRKYNKTFITVVVFCSILMIQIIPVALGASSSYLNVKLSDYTAYIDGVKLPVYSVNGNLMINLNHLNYYGFKVSSSDTTVLCYRDASRQITGIPKSQWATKYNVVSIKPRNKCYLNGKEIPVLYLNNQPFIFLNELYEDNIVKVNGKNVNITLGIVDGLQKTQKSLEQMDYMIKILNLDTDITEYSVAYIYYDPITKLTMVNFADNVLDIFEEKAEKNYTLLQMYVVLCKHYPEGSYTQELYINEDWKKWSDYYIKQDYINKLKFIYSLYQKANGNSPVYVIGAEVKEASIGYPQAELKIFNFSAMPIDAVEVSFKCYNLFDQPALNESQSNQFVGIKQKISIPAFDSSVVSFDLTRYPSAGKIKNVLIRKVHFIDNKIWINPATGNSKKL
>NC_015949.1|WP_014043376.1|2571683_2572103_+|YgiT-type-zinc-finger-protein
MGKKCFFCGAEMKKEITSVESGWGEYTFKIEGVHAYVCHECGEKIFEPKEAEMILELGRALSFLPNEERPAPNEVLDINGIHDFLKILSSSIFSLITNKDIKLQRKKINGFFKQKIYSKFCTTGLVFIITTTMPWDYDY

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Crispr_ID: NC_015949_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_3

2564413-2566152

TypeIII-A,TypeI-B

Consensus_repeat	Method
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	PILER-CR
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CRISPRCasFinder
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CRT

26 spacers

cas8b1,cas7b,cas5,cas3,cas4,cas1,cas2,cas6

The CRISPR arrays of NC_015949_3

>merge|NC_015949|3|2564413-2566152|PILER-CR,CRISPRCasFinder,CRT
GTTTGTAGCCTTCCCGTTGGGGATTGAAACCGAAAATATACCGATTGCCAAGTTTAAGATGAGGAGTTTGTAGCCTTCCCGTTGGGGATTGAAACGTAATTAGGAGGTAGGTAATCATGAGAATTTGGGTGTTTGTAGCCTTCCCGTTGGGGATTGAAACAATATTTCACAAACTTTTGAAAAATTTTTAGTGCAGGTTTGTAGCCTTCCCGTTGGGGATTGAAACAATATTTCACAAACTTTTGAAAAATTTTTAGTGCAGGTTTGTAGCCTTCCCGTTGGGGATTGAAACACTCATTTCTTTGCTACCTATTGCAACCTTTATTTCAGTTTGTAGCCTTCCCGTTGGGGATTGAAACGGATTGAGAGGTTAGAAGACAGAAAAGAGACAAAAAGTTTGTAGCCTTCCCGTTGGGGATTGAAACTTATAATATACTTGATAACCCCATCCTTCTTTTTGGTTTGTAGCCTTCCCGTTGGGGATTGAAACGCACCTAATTGGTGATACATTTTCAAGGACTGGAGGGTTTGTAGCCTTCCCGTTGGGGATTGAAACTTAGTTGCCTTGAAAGCTTTTGACGAATTCTATACAGTTTGTAGCCTTCCCGTTGGGGATTGAAACTAATATACCAATGTCTGTCCTGCAACAATGTTTTGTGGTTTGTAGCCTTCCCGTTGGGGATTGAAACTTGTTAAACACTTTTACAACCTCCATTCTTGATTGGTTTGTAGCCTTCCCGTTGGGGATTGAAACTGGAACGTATCAGGTCGGGTCTACTTGGTAACACCGAGTTTGTAGCCTTCCCGTTGGGGATTGAAACTAATTCGACACACGTTACAAAAATCCTTTTTCTCGGTTTGTAGCCTTCCCGTTGGGGATTGAAACTCGGGCAGGTGGTAAGCATTTTGCGAAAATTTGTTTGTTTGTAGCCTTCCCGTTGGGGATTGAAACAGTTGGGGGAGAGCTCTGTTTATATAGGTATTGAAAGTTTGTAGCCTTCCCGTTGGGGATTGAAACTTGTAACCTTTTGCAACATTATTTAACGCTGTCGAGTTTGTAGCCTTCCCGTTGGGGATTGAAACTTGAACAATACTTTTTAATTAACTCCATTAACATTTGTTTGTAGCCTTCCCGTTGGGGATTGAAACAGATTTCTTTGGCTATGTCTTCTTCAAGATACATAGTTTGTAGCCTTCCCGTTGGGGATTGAAACCGGGAAAGAATTTACAACAAACAAATACAGTGATAGTTTGTAGCCTTCCCGTTGGGGATTGAAACATACCCCGTCGTTTCGCTTACTTTTCTAAATGCTTCGTTTGTAGCCTTCCCGTTGGGGATTGAAACATGTCCTTTTCTGTATCTATTTTTTCTATTGCTCTGAGTTTGTAGCCTTCCCGTTGGGGATTGAAACTAGGCATGGATGATTTGTTTGAGAAAATTGAAAGTAGTTTGTAGCCTTCCCGTTGGGGATTGAAACGCACACCGTGAGTACTTTCTCACAGTGTGCTCCTGCGTTTGTAGCCTTCCCGTTGGGGATTGAAACTTTTTATTTTTTTCAAACCCCAAAGGGTAGGCTACGGTTTGTAGCCTTCCCGTTGGGGATTGAAACACAGGTATCTCACAATCATATATTAGTGAACTTGAGTTTGTAGCCTTCCCGTTGGGGATTGAAACATTTATATAACCCTCTACATACTCATTTATCTTCCGTTTGTAGCCTTCCCTTTGGGGATTAAGAG

>NC_015949|3|3|2564413-2566087|PILER-CR
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CGAAAATATACCGATTGCCAAGTTTAAGATGAGGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GTAATTAGGAGGTAGGTAATCATGAGAATTTGGGT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AATATTTCACAAACTTTTGAAAAATTTTTAGTGCAG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AATATTTCACAAACTTTTGAAAAATTTTTAGTGCAG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACTCATTTCTTTGCTACCTATTGCAACCTTTATTTCA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GGATTGAGAGGTTAGAAGACAGAAAAGAGACAAAAA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTATAATATACTTGATAACCCCATCCTTCTTTTTG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GCACCTAATTGGTGATACATTTTCAAGGACTGGAGG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTAGTTGCCTTGAAAGCTTTTGACGAATTCTATACA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TAATATACCAATGTCTGTCCTGCAACAATGTTTTGTG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTGTTAAACACTTTTACAACCTCCATTCTTGATTG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TGGAACGTATCAGGTCGGGTCTACTTGGTAACACCGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TAATTCGACACACGTTACAAAAATCCTTTTTCTCG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCGGGCAGGTGGTAAGCATTTTGCGAAAATTTGTTT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AGTTGGGGGAGAGCTCTGTTTATATAGGTATTGAAA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTGTAACCTTTTGCAACATTATTTAACGCTGTCGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTGAACAATACTTTTTAATTAACTCCATTAACATTT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AGATTTCTTTGGCTATGTCTTCTTCAAGATACATA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CGGGAAAGAATTTACAACAAACAAATACAGTGATA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ATACCCCGTCGTTTCGCTTACTTTTCTAAATGCTTC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ATGTCCTTTTCTGTATCTATTTTTTCTATTGCTCTGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TAGGCATGGATGATTTGTTTGAGAAAATTGAAAGTA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GCACACCGTGAGTACTTTCTCACAGTGTGCTCCTGC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTTTTATTTTTTTCAAACCCCAAAGGGTAGGCTACG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACAGGTATCTCACAATCATATATTAGTGAACTTGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC

>NC_015949|3|3|2564413-2566152|CRISPRCasFinder
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CGAAAATATACCGATTGCCAAGTTTAAGATGAGGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GTAATTAGGAGGTAGGTAATCATGAGAATTTGGGT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AATATTTCACAAACTTTTGAAAAATTTTTAGTGCAG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AATATTTCACAAACTTTTGAAAAATTTTTAGTGCAG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACTCATTTCTTTGCTACCTATTGCAACCTTTATTTCA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GGATTGAGAGGTTAGAAGACAGAAAAGAGACAAAAA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTATAATATACTTGATAACCCCATCCTTCTTTTTG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GCACCTAATTGGTGATACATTTTCAAGGACTGGAGG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTAGTTGCCTTGAAAGCTTTTGACGAATTCTATACA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TAATATACCAATGTCTGTCCTGCAACAATGTTTTGTG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTGTTAAACACTTTTACAACCTCCATTCTTGATTG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TGGAACGTATCAGGTCGGGTCTACTTGGTAACACCGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TAATTCGACACACGTTACAAAAATCCTTTTTCTCG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCGGGCAGGTGGTAAGCATTTTGCGAAAATTTGTTT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AGTTGGGGGAGAGCTCTGTTTATATAGGTATTGAAA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTGTAACCTTTTGCAACATTATTTAACGCTGTCGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTGAACAATACTTTTTAATTAACTCCATTAACATTT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AGATTTCTTTGGCTATGTCTTCTTCAAGATACATA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CGGGAAAGAATTTACAACAAACAAATACAGTGATA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ATACCCCGTCGTTTCGCTTACTTTTCTAAATGCTTC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ATGTCCTTTTCTGTATCTATTTTTTCTATTGCTCTGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TAGGCATGGATGATTTGTTTGAGAAAATTGAAAGTA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GCACACCGTGAGTACTTTCTCACAGTGTGCTCCTGC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTTTTATTTTTTTCAAACCCCAAAGGGTAGGCTACG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACAGGTATCTCACAATCATATATTAGTGAACTTGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ATTTATATAACCCTCTACATACTCATTTATCTTCC
GTTTGTAGCCTTCCCTTTGGGGATTAAGAG

>NC_015949|3|3|2564413-2566152|CRT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CGAAAATATACCGATTGCCAAGTTTAAGATGAGGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GTAATTAGGAGGTAGGTAATCATGAGAATTTGGGT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AATATTTCACAAACTTTTGAAAAATTTTTAGTGCAG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AATATTTCACAAACTTTTGAAAAATTTTTAGTGCAG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACTCATTTCTTTGCTACCTATTGCAACCTTTATTTCA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GGATTGAGAGGTTAGAAGACAGAAAAGAGACAAAAA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTATAATATACTTGATAACCCCATCCTTCTTTTTG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GCACCTAATTGGTGATACATTTTCAAGGACTGGAGG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTAGTTGCCTTGAAAGCTTTTGACGAATTCTATACA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TAATATACCAATGTCTGTCCTGCAACAATGTTTTGTG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTGTTAAACACTTTTACAACCTCCATTCTTGATTG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TGGAACGTATCAGGTCGGGTCTACTTGGTAACACCGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TAATTCGACACACGTTACAAAAATCCTTTTTCTCG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCGGGCAGGTGGTAAGCATTTTGCGAAAATTTGTTT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AGTTGGGGGAGAGCTCTGTTTATATAGGTATTGAAA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTGTAACCTTTTGCAACATTATTTAACGCTGTCGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTGAACAATACTTTTTAATTAACTCCATTAACATTT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AGATTTCTTTGGCTATGTCTTCTTCAAGATACATA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CGGGAAAGAATTTACAACAAACAAATACAGTGATA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ATACCCCGTCGTTTCGCTTACTTTTCTAAATGCTTC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ATGTCCTTTTCTGTATCTATTTTTTCTATTGCTCTGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TAGGCATGGATGATTTGTTTGAGAAAATTGAAAGTA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GCACACCGTGAGTACTTTCTCACAGTGTGCTCCTGC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTTTTATTTTTTTCAAACCCCAAAGGGTAGGCTACG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACAGGTATCTCACAATCATATATTAGTGAACTTGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ATTTATATAACCCTCTACATACTCATTTATCTTCC
GTTTGTAGCCTTCCCTTTGGGGATTAAGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_014043365.1\|2550738_2551974_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293879
NC_015949.1\|WP_014043369.1\|2557726_2560150_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_015949.1\|WP_014043376.1\|2571683_2572103_+\|YgiT-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|240606
NC_015949.1\|WP_014043379.1\|2575946_2576273_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273806
NC_015949.1\|WP_014043374.1\|2567716_2568892_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043367.1\|2556165_2557158_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_015949.1\|WP_013404366.1\|2555896_2556160_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015949.1\|WP_014043364.1\|2549024_2550722_-\|Hsp70-family-protein	unknown	unknown	gnl\|CDD\|212667
NC_015949.1\|WP_014043366.1\|2554908_2555907_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|368098
NC_015949.1\|WP_014043383.1\|2580520_2581144_-\|hypothetical-protein	cas6	mkCas0062_cas6_CAS-I:CAS-III	unknown
NC_015949.1\|WP_014043371.1\|2561013_2561898_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_015949.1\|WP_014043381.1\|2578100_2579951_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043378.1\|2575184_2575841_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NC_015949.1\|WP_014043377.1\|2572267_2572759_-\|DUF3368-domain-containing-protein	unknown	unknown	gnl\|CDD\|225269
NC_015949.1\|WP_014043368.1\|2557199_2557697_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_015949.1\|WP_014043380.1\|2576298_2578095_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|223510
NC_015949.1\|WP_014043370.1\|2560239_2560992_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09692_cas5_CAS-I-B	gnl\|CDD\|187823
NC_015949.1\|WP_013433677.1\|2572769_2573036_-\|UPF0175-family-protein	unknown	unknown	gnl\|CDD\|377095
NC_015949.1\|WP_014043372.1\|2561919_2563983_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_015949.1\|WP_014043382.1\|2580256_2580394_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_014043365.1\|2550738_2551974_-\|hypothetical-protein	gnl\|CDD\|293879	cd16269, GBP_C, Guanylate-binding protein, C-terminal domain. Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.	0.00457754
NC_015949.1\|WP_014043369.1\|2557726_2560150_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.9376e-46
NC_015949.1\|WP_014043376.1\|2571683_2572103_+\|YgiT-type-zinc-finger-protein	gnl\|CDD\|240606	cd12870, MqsA, antitoxin MqsA for MqsR toxin. This family includes domains similar to the antitoxin MqsA that binds motility quorum-sensing regulator MqsR, a toxin that is highly upregulated in persisters (dormant cells found in biofilms that are a source of antibiotic resistance), thus forming a unique toxin:antitoxin (TA) pair. MqsA neutralizes MsqR toxicity. It binds its own promoter as well as those of genes important for E. coli physiology, such as mcbR and spy. It also binds zinc and has been shown to coordinate DNA via its C-terminal domain. This family also includes the B. subtilis YokU protein, which is functionally uncharacterized.	3.86959e-07
NC_015949.1\|WP_014043379.1\|2575946_2576273_+\|hypothetical-protein	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.4693e-08
NC_015949.1\|WP_014043367.1\|2556165_2557158_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	9.9555e-159
NC_015949.1\|WP_013404366.1\|2555896_2556160_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.57908e-32
NC_015949.1\|WP_014043364.1\|2549024_2550722_-\|Hsp70-family-protein	gnl\|CDD\|212667	cd10170, HSP70_NBD, Nucleotide-binding domain of the HSP70 family. HSP70 (70-kDa heat shock protein) family chaperones assist in protein folding and assembly and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). Some HSP70 family members are not chaperones but instead, function as NEFs to remove ADP from their HSP70 chaperone partners during the ATP hydrolysis cycle, some may function as both chaperones and NEFs.	1.89799e-88
NC_015949.1\|WP_014043366.1\|2554908_2555907_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|368098	pfam04754, Transposase_31, Putative transposase, YhgA-like. This family of putative transposases includes the YhgA sequence from Escherichia coli and several prokaryotic homologs.	8.38843e-18
NC_015949.1\|WP_014043371.1\|2561013_2561898_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	3.0147e-70
NC_015949.1\|WP_014043378.1\|2575184_2575841_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.19636e-07
NC_015949.1\|WP_014043377.1\|2572267_2572759_-\|DUF3368-domain-containing-protein	gnl\|CDD\|225269	COG2405, COG2405, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	1.90428e-34
NC_015949.1\|WP_014043368.1\|2557199_2557697_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.42795e-72
NC_015949.1\|WP_014043380.1\|2576298_2578095_-\|ATP-binding-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	2.70685e-17
NC_015949.1\|WP_014043370.1\|2560239_2560992_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187823	cd09692, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.24356e-26
NC_015949.1\|WP_013433677.1\|2572769_2573036_-\|UPF0175-family-protein	gnl\|CDD\|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	6.25062e-14
NC_015949.1\|WP_014043372.1\|2561919_2563983_-\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	7.76302e-142

>NC_015949.1|WP_014043372.1|2561919_2563983_-|TIGR02556-family-CRISPR-associated-protein
MIEEIVEIGDILIGVSSGNEAYLSALIEEIEVPSGNEKNFVAKINFSTKEKIITIDCAEEVKDSTAKDYVYVGSAEGSNSPQWFASTKSFAYFLTETIPNLAERSIPVVSDICKKILDDYFVNIKEYLLSSAELTEEEKMLLNQRIEKKYMYFLNTDHVMVNDNKKLTERPISQIYKELIRKGKSTDKVFKQLRDAFTKECTDGLKKLTELKPQQIGLYVLCVDGKPLTSYPEYVEAVVAYKRQVKKGAEKTGEKQKEGNICYICLGTDGLSFEGLKKPKFKYFTTNQNIFASYLDQKNYAKNITVCEKCLSKLVAGDIFLRNKLKTQFGSFDVYVLPTFVYTSAKLTKNYLEDLTLNITNSLNTAWNYNRLEKLRDDISNFLSFFDQNHYFLLNLIFYREAQAGTKIMKFIPDINPSIFDKIYNAASKVFSQYIDIIGNDPSFRISLESIYYSVPIRLKNRNESTEAQRLLNIYDAIFSGKRIARDFLIENFIKAVGVVVYGKEGYNLSKFIGNDIALMVIRMVFVMKFLEFLDCLEVERGMDVSQLNLSDDLKSYIQQMNYDEPKTALFLLGVLIGEIGAKQYLATKDRQDDSAGHKPILNKINYNGIDRPKLIRLCSDVHNKLRQEKLLPYTEMIFAEMKRLLDKHIDSWKLDKYETLFYILSGYAYKTQKVILNASNSQETSN
>NC_015949.1|WP_014043371.1|2561013_2561898_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MEKKIIDKNSEILFTYDAKLCNPNGDPDEENRPRMDWEKEINLVSDLRVKRYIRDYLDDKGIPIYVRKIDGKSVKPEEVIKSVGEDIDELETFIDIRLFGATIPIKGETRTYIGPVQFNWGYSLNKVELLEASITSHFASREKNQQGAIGKDYRVKYSFIAFSGIVSAKRAKITRLTEDDVRFLDRAMKEAIPLQATRSKIGQYPRLYMRVEYVDDKTLLGDLRDYIRLIEVVEKPRKIEDVQLDITSLVEFLEKNKDEISKIYYFKHPDLCLVCGGNAVDFKDAFGTFELEEV
>NC_015949.1|WP_014043370.1|2560239_2560992_-|type-I-B-CRISPR-associated-protein-Cas5
MKFLVFDLKGKFAHFRKFYTNSSSLSYLVPPRTVVEGVVAAILGFERDSYYEELSAENLLIAVQKIERTYKIVQTVNYIKATSVNELKNPNTHTQVPLELLAGYNGFVGFRVFVMPRDEKMYSQLKSKLESGRAEFPIYFGSAPFAAKTEFVGEFEAYRWEDSSARILTVLDTGLMKSLNLSLESSAGLALMKDRMPCDFDKDRFATKVKTYINDENLNPIWVDLDSSAQDKVYFIKEFSSDKELCISLM
>NC_015949.1|WP_014043369.1|2557726_2560150_-|CRISPR-associated-helicase/endonuclease-Cas3
MEYYSHKNPDKLLYDHLLEVYHYAMEANVELKSWEKEALQVICLCHDFGKFTTFFQSHLNGVLNKYSQHGFISALFGVFCWMQKKGLWLQQMKNQISEDEVVSLLIYACILHHHGDVKDISKNLPEKFAGDFKADINLVQKIDDAYVQIEDLRCNAEDIKPLLEKIGLGSEFEKFLAQQRGFIEDILRYLKRIEYGIRFIGVMPQALKDGTELYFIQQKLYSLLIWADKMSAANYKVLSPCYASSDRLIVARNKVIRPTADKNLQRIRQSVFEAVLSNIEKNKEKDIFSITTPTGTGKTLAGVFAAVKLKELLKKSGRIIYALPFTSIIDQNYDVVKNLFEAIEDFEKNRDRYLLKHHHLTDGEYRGKEEALKEITDEITVYEKVASECFIENWTSGFVVTTFVQLLETLISNRNRMLKKFHAFYDSILILDEIQAIEVDLLPLVEEVLRKLSKLFKCKIILMTATKPLIFEDACELAGFCDYSIFNRTKLVYHHSDLKVAEFVDFFLEQVYEDEKSFLIVANTINQSLQIYNGIKNNLKDKEVIYLSANLVPRDRKEVIKKIEEALESGRKPIVVSTQVIEAGVDIDFDCVIRDIAPIDSIIQCAGRCNRHNQKSQGKVLVVNIKDDSGRSFAKRVYGNTAIEISNMLLLQHPEVEEKDYGMLIDNYFRMVKENKSFKKSEEFLRSIRLLKFDSILEKEELTISRFSLIQQRGGYVSVVIRSNEEIEDAYQSYINSFSIKDYYKRREIYLELKNILFEHTISVPSKYVQILAEEKGILSLPPTSCERYYNPETGFVYDPNDNVIFA
>NC_015949.1|WP_014043368.1|2557199_2557697_-|CRISPR-associated-protein-Cas4
MDVYMTGVYIWYYNICKRQVWLMAHGVLPDENDDNIVLGRFLHEYYYKKDQKEIKFGNAVFDILYQDKDEIVIGETKKSSRFKEASRYQLLFYIKLLKEAGISAKGVLFYPEERKKEEVELTVEDEEKLQKMIAEIETIIEKDSPPPAAYCRYCPKCAYREYCFA
>NC_015949.1|WP_014043367.1|2556165_2557158_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKDLYVFNSGFLRRKDNTIMFETDEGKKYFPVEEIESVFIFGEVDINKRFLEFMTEKNICVHFFNRYEYYVGTYYPREHYNSGIVILKQVEFYNDYNKRMTIARSIVEGAVLNMLVVLRYYNSRGNILKDEIETIERMRHNINSCDDVNTLMALEGNIREIYYRCFNKILDDENFTFVRRSKNPPLDRINALISFGNSLLYATTLGEIYQTQLDPRIGYLHSTNQRKFSLNLDISEIFKPIIVDRVIFSLVNKKVLSEKHFERELNGIILNDQGKKLFVSEYNQKLYSTITHPKLNCQVSYKRLIRMEAYKLQKLFLENIEYKPFVARW
>NC_015949.1|WP_013404366.1|2555896_2556160_-|CRISPR-associated-endonuclease-Cas2
MFVILVYDVNEKRVAKALKKCRQYLTWVQNSVFEGNISEGTLRRLILELERILDLSEDSVIIYKFQNTWYSERQIIGIEKNPVDFMT
>NC_015949.1|WP_014043366.1|2554908_2555907_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MCEKLPPKEHDTTFKFLFADKEEILLLVKDILHYTWADNIEEDTIELVKTNYVTQQFSQVEADVVAKAKLKDKEVYFYILIENQSKVKREMQQKILKYMISLWAEEIRKGVQILPAIIPIVVYNGIGERWNVSTDLMEAFDVFKDDVFRYRVVDIIELDVKKLLEREEDVLTPIVFYLEQAREDRSELIGRLLEVEKNLKKLSKKNVDRFLEWSYHIIRPRLAEDQKSEFDRIAKRVKQEGVEAMGEFISNVARLLDEAKTKDFLAGKLEGKLEGKIEGKIEGKLEGKLEATIEFAKRLIQKGFSDEEVAELTELQIEKVKELRKSFKNTMS
>NC_015949.1|WP_014043365.1|2550738_2551974_-|hypothetical-protein
MHSAEHKEENTLTKRPDFPKDATPKQNTSYKLLLRKELKNVQNFGKFFFELDVLTIAGVSRCLKDGNNFESVKRFVKERLERYQFDANEIHLIIDYLNADNFSFKLMVNEGIERIEKDRFIIEAFVKCYIARYFANRLFEGKKGLMKEIEKDFSEMCGQENLYFFGELKKWIISYDIWPKTAQQYAEIASSFKDEIEDVYSKVFSEVQKRRLIKIGKKKDHQEESQNIAEKAVKSQAEAVAGTRENEEFRKLKEKLENYELMVNMLQEQIEELREINSELQKEREMLLQERQQLPEKILIKLFNDLNSPQFGNLLDKIYVYANDLEPVDSSTAQEIFTNIISVLSLYNIVGHLSKEEYKSTISIKKEEIGSIYRCDRPAQSDKQVYEAQILYPKWTYNQKTVANKFVRIKS
>NC_015949.1|WP_014043364.1|2549024_2550722_-|Hsp70-family-protein
MHIGIDLGTTNTVVSYAKRKARGGVEPQVMRITQLDEYNSSIQEEILPSVLFLDFDGNIVIGKKAKHMKQYHPGRTISNSKRYMGTSMVFRIEDRAFTPVDVAANILKVCKRTIELNLGGKPVQQVTITVPASFNTDQIRDTRNAALKAGFDPDRIRIIPEPTAAFIDFINEQSELVEEDRLVDISTPKRVLVFDLGGGTCDIVVMDVVQSGNCLKVEEKAVGRYSELGGIDFDLAATRYLLQKFFVDNKIKEGDVEPVEQSQMVNKLMAFCEKAKEFFSNQMMLNPEIESTNPSFKMNIPEFWRGKSQLFSITLKEYNTATRDLYHSSGIKAKTIEDYERCKNIVDPIYETLERYEIDKNSIDYIFATGGMSLYYKVVQRLKELFPKSQVIKASNPLEAVSRGAAIFSFYEVEIKRQNEKASISKPTIKEPSSAEMEIVTKTVLAEAIMIDVEEGLPREIISKNQPVPYKGVIRDSFRVTSPSGIKIDIYAGEDPYDCKMRIQKSFTGNFRSPVTPGTPLDIEYEIDENKYLKLRVVVKDNMNPPIDLDVDSDVKTVGLEKVKE
>NC_015949.1|WP_014043374.1|2567716_2568892_-|hypothetical-protein
MRKYNKTFITVVVFCSILMIQIIPVALGASSSYLNVKLSDYTAYIDGVKLPVYSVNGNLMINLNHLNYYGFKVSSSDTTVLCYRDASRQITGIPKSQWATKYNVVSIKPRNKCYLNGKEIPVLYLNNQPFIFLNELYEDNIVKVNGKNVNITLGIVDGLQKTQKSLEQMDYMIKILNLDTDITEYSVAYIYYDPITKLTMVNFADNVLDIFEEKAEKNYTLLQMYVVLCKHYPEGSYTQELYINEDWKKWSDYYIKQDYINKLKFIYSLYQKANGNSPVYVIGAEVKEASIGYPQAELKIFNFSAMPIDAVEVSFKCYNLFDQPALNESQSNQFVGIKQKISIPAFDSSVVSFDLTRYPSAGKIKNVLIRKVHFIDNKIWINPATGNSKKL
>NC_015949.1|WP_014043376.1|2571683_2572103_+|YgiT-type-zinc-finger-protein
MGKKCFFCGAEMKKEITSVESGWGEYTFKIEGVHAYVCHECGEKIFEPKEAEMILELGRALSFLPNEERPAPNEVLDINGIHDFLKILSSSIFSLITNKDIKLQRKKINGFFKQKIYSKFCTTGLVFIITTTMPWDYDY
>NC_015949.1|WP_014043377.1|2572267_2572759_-|DUF3368-domain-containing-protein
MIVVSNTTPIIVFAKLERLDILENLFGTIYISPSVYQELTYSSKFEEEKGRIMNAAFLKIKELRNEFAAEILQRTQAIDKGESETIILAKESNADLLIMDEKKGRSVAKLLGLRLTGSLGILLKAKEVGVVSQIEPLIKKLIKENIRISPQLVEEILKQAKEK
>NC_015949.1|WP_013433677.1|2572769_2573036_-|UPF0175-family-protein
MEGIKIEIELPKEILNYISLNEITNDKVLKELIIYKLIKDEKISFGKGAEILGMSKIELIEELSEYGVNYFDQPIEEVIEDKNAIDKM
>NC_015949.1|WP_014043378.1|2575184_2575841_+|MFS-transporter
MVLLTIAISLPHSVLTVLLLAKGITLSQIMIIQAGYSFAVLISEYPSGLIADMYSKKMVFICSKLFLLLMFCLVISMNNFWMLLIAWFMYGISSALDTGTIEAEIINQLKLSGMQIDKFISNSNRLNFIALLIGSSIGSFIYYAIGIKLYWISIILTIVSTICVGIFYKGETSEKTKISLFEIFKRMLVQSKDGIKEMRKKESLKLMIALELALCYVC
>NC_015949.1|WP_014043379.1|2575946_2576273_+|hypothetical-protein
MKLAEEQKSEYDGIAKRVKQEGVEAMGEFISNVARLLDEAKTKYFLAGKLEGKLEGKIEGKLEGKLEATIEFAKRLIKKGFSDEEVAELTELQIEKVKELKKVHGKLT
>NC_015949.1|WP_014043380.1|2576298_2578095_-|ATP-binding-protein
MFNTEIVGRMMKYDSDIYSRYRAEIWFDYTKKAMNEIKEGALLAVQNFSSTSDKIRYCILEITSVIPLHYGLDNDLSGYPGFLTEAAENIYRDWEEQEEEPLDDATKIRCLAIPTNFEIIIDKDQKVSIGIESNLPMVGAEAFLLDEELTNRILNYDIDKSGDVIEIGHLIRDENVKILLKVEELLRVHFGVFGFTGAGKSNLLSTLVRKILTESNLPVKIVIFDLMGEYSTLLVDLLVKLNNSMIVGIGEKTFVGSLISLMKADRSLPEYKDLLKKATIDVVNSSLYPKGLVSHKDLFKKAFFRILQSRKVKIWQSGDIAVADFAKMYERTLLKGNLGKSEALIKKLYEQLLRKTNPLNATVCLALIQYIENKYLSDEKLGSIARSNLELFVNELKKKYEELKEFGFSNENVIDQKKLIEILNSPDDKALVIFQSHDPDELRNLAYQIGMAIFEDRRRSGKIDPVVSFIFDEADEFIPQDAKDSYERSSEVVMHLARRGRKFGLGIGIATQRITYLNTNIMAQPHTYFVSKLPRKSDQERITDAFGISEDMFKQTFKFKKGCWLLVSYDAIGLEAVPLPIYVQNANDAVLEFLKTLQ
>NC_015949.1|WP_014043381.1|2578100_2579951_-|hypothetical-protein
MSKLSQIYGYWKNSIKASMKRYDENMERSLKHLQNFYNMVLKDYIIDWSRYFESQPFRHSLRQKIENFFGKNEINFVAIDGTCVKDEGSDFITFFAGAYGARGKIIIKHEGEKIKYERWDFARDVTMVAQIPVFPYEIEFVASSPELSQMQFYSDKDIQEILNLHTSLMKLAEIYLAYHVVSSSTVDIPQIILLDLAPSTLLRVPYVNYKSTNYLGYKYLNDTIKLSDVIVALSHPYNSLLGVPSRKKYRRYALLLSKLDEVCSQNHKNYFTYKELTEICHLSIEDIKEIVRFLDATGVVEDDEAAGIKLFVNLSQRWSYLVSFFDYICNQIFIRKNPTALEFSNFSEESNIKKLISHDDINFLISIGIRALIEKCWEKNVFLIGIVKDSKSRYFCRNFLNVLSSQNMLGDGKENVDIKNFQIAMSDRLVFENCAALSTELCAPWSSVEFDSAFATLFVDRNNSVTGVKGHIVADDRIFAKSIAQFYLQRSKKQCKMGHAIFVERLLHPSLDRQFLDLVLLENSKLGRLSPFIHLDKKVINWGQAMNIYFLDVLTRNHFPEVIGYPEPLHKADRGAKTLLRFAKGVIHSSQQLYRKDPLNMTFRKFRDKLEFEDEE
>NC_015949.1|WP_014043382.1|2580256_2580394_-|hypothetical-protein
MSLSALLGASIMMHGLVQGLKVFAVVVVLGFVIKGLWQGFKKELA
>NC_015949.1|WP_014043383.1|2580520_2581144_-|hypothetical-protein
MMGCDEKVAKYFTFHFWAREDGVFLPSSYYSKVYEVLKSLLATEQFTISPIKTKNKKEVEDGVWVFEDFRIYLATPFLELFTQNILKIYETLNGLFEGIYLKKISCRSQQPKASGILLSGVFAQKDGVCLEYDRQPEIFSDGLRRQLLNIYYQRFGAYPEDQRFFFVIKDGLKKQHLIRSRIEYFGRYEIFASSELLDMFCQMFCVK

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Crispr_ID: NC_015949_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_4

2569259-2571209

TypeIII

Consensus_repeat	Method
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	PILER-CR
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CRISPRCasFinder
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CRT

29 spacers

cas8b1,cas7b,cas5,cas3,cas4,cas1,cas2,cas6,csm5gr7

The CRISPR arrays of NC_015949_4

>merge|NC_015949|4|2569259-2571209|PILER-CR,CRISPRCasFinder,CRT
GTTTGTAGCCTTCCCTTTGGGGATTGAAACTGATAAAAACCACAACCATTGTTTGTATTTTTCCATGTTTGTAGCCTTCCCTTTGGGGATTGAAACCTTCAAAAAGAAGAAAACAGTTAAGTATCGCTGTAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACTTCTATCTTCTTCAAAACTCCACAATTTGGGTAAACGTTTGTAGCCTTCCCTTTGGGGATTGAAACCCCCTCCTTAATTTATTTTTCATCCCCAACTTGAAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACCACAAAATTATAGTTTTGTGCAGTATGAACCCTGCGTTTGTAGCCTTCCCTTTGGGGATTGAAACACTCTCTCTAATTACTAATTAATTTTTTATTTTTTGTTTGTAGCCTTCCCTTTGGGGATTGAAACTTGCTTCCCAATCTAAAATTTTTCGAGCCTTTAGAGTTTGTAGCCTTCCCTTTGGGGATTGAAACGGTTTTTCGGTCTTTTCCCATTTTTTGTTTTTGCCAGTTTGTAGCCTTCCCTTTGGGGATTGAAACATTTTTTCAATGTGTTAAATTGGTTTAATAGATTTGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCTGGTATATTCTCCACCCAGTCTCTCCCCCAGCTTGTTTGTAGCCTTCCCTTTGGGGATTGAAACAGACATAGAATAACACTGCAAAAAAACATTCCCATAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACAATTGTCGCTCTCAAAGATGTAACCCACGTTATACGGTTTGTAGCCTTCCCTTTGGGGATTGAAACAAATCAACTAAAACTCCAATCTCTCTACCTCTTTGTTTGTAGCCTTCCCTTTGGGGATTGAAACCATCAATAAATCTAATACACCTTTAAAAAATTCCAGGTTTGTAGCCTTCCCTTTGGGGATTGAAACCCGTCAATGATTCTTTTGATTTTTCCTTCTCCTTTGTTTGTAGCCTTCCCTTTGGGGATTGAAACAAATTTTCATTCTAAACCCTCCTTTTCTGTTTTTTGTTTGTAGCCTTCCCTTTGGGGATTGAAACAAAAACTCCAAGCGTGCTGCCTTGTAACCGTGGTGGGTTTGTAGCCTTCCCTTTGGGGATTGAAACACGACTGCAAAATTTCTTCTACATCTTTTTTTGATGGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCAAGAACAATATTGTTTGTTGTGTCTTCCTCATGCTCGAGTTTGTAGCCTTCCCTTTGGGGATTGAAACAACAACGCTCCACTCATCTAAAGCTTCCTTGTCAAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACATATTTATCTTTATGTTTGTTACTACTACTCTTTCGTTTGTAGCCTTCCCTTTGGGGATTGAAACAGGAAGGGCTTTCAAAATTTTTAAAAGGAGGAGAACGTTTGTAGCCTTCCCTTTGGGGATTGAAACAGCAATAAAAATTTTGCTTCAAAAAGAAGAAAACAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACGCCAAACATACAACCATCGCCAATTCATCAATTCGTTTGTAGCCTTCCCTTTGGGGATTGAAACACTTCTGGTTTAACTACATGAGAAACAAAACAAAGAGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCCATGTGACCAAACTCAGATGCCACCATGCAGTACAGTTTGTAGCCTCCCCGTTGGGGATTGAAACTGATTAGAACCTTCCTCTTTCCCTCCTTTCTTTCAGAGTTTGTGGCCTTCCCGTTGGGGATTGAAACATGAAATTTCCCTTATGAAAATAGTTCCGGTAAACAGTTTGTAGCCTCCCCGTTGGGGATTGAGGAAGGAGGGGGTTTGTAGCCTTCCCGTTGGGGATTGAGGAGTAAGAATTGTTTGTTGCCTATCCTTGGAAAATTGAGAA

>NC_015949|4|4|2569259-2571066|PILER-CR
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGATAAAAACCACAACCATTGTTTGTATTTTTCCAT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTTCAAAAAGAAGAAAACAGTTAAGTATCGCTGTAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTCTATCTTCTTCAAAACTCCACAATTTGGGTAAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCCCTCCTTAATTTATTTTTCATCCCCAACTTGAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CACAAAATTATAGTTTTGTGCAGTATGAACCCTGC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACTCTCTCTAATTACTAATTAATTTTTTATTTTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTGCTTCCCAATCTAAAATTTTTCGAGCCTTTAGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GGTTTTTCGGTCTTTTCCCATTTTTTGTTTTTGCCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATTTTTTCAATGTGTTAAATTGGTTTAATAGATTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTGGTATATTCTCCACCCAGTCTCTCCCCCAGCTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGACATAGAATAACACTGCAAAAAAACATTCCCATAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATTGTCGCTCTCAAAGATGTAACCCACGTTATACG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAATCAACTAAAACTCCAATCTCTCTACCTCTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CATCAATAAATCTAATACACCTTTAAAAAATTCCAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCGTCAATGATTCTTTTGATTTTTCCTTCTCCTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAATTTTCATTCTAAACCCTCCTTTTCTGTTTTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAAAACTCCAAGCGTGCTGCCTTGTAACCGTGGTGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACGACTGCAAAATTTCTTCTACATCTTTTTTTGATG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCAAGAACAATATTGTTTGTTGTGTCTTCCTCATGCTCGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACAACGCTCCACTCATCTAAAGCTTCCTTGTCAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATATTTATCTTTATGTTTGTTACTACTACTCTTTC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGGAAGGGCTTTCAAAATTTTTAAAAGGAGGAGAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGCAATAAAAATTTTGCTTCAAAAAGAAGAAAACAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GCCAAACATACAACCATCGCCAATTCATCAATTC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACTTCTGGTTTAACTACATGAGAAACAAAACAAAGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCCATGTGACCAAACTCAGATGCCACCATGCAGTACA
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TGATTAGAACCTTCCTCTTTCCCTCCTTTCTTTCAGA
GTTTGTGGCCTTCCCGTTGGGGATTGAAAC

>NC_015949|4|4|2569259-2571209|CRISPRCasFinder
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGATAAAAACCACAACCATTGTTTGTATTTTTCCAT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTTCAAAAAGAAGAAAACAGTTAAGTATCGCTGTAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTCTATCTTCTTCAAAACTCCACAATTTGGGTAAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCCCTCCTTAATTTATTTTTCATCCCCAACTTGAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CACAAAATTATAGTTTTGTGCAGTATGAACCCTGC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACTCTCTCTAATTACTAATTAATTTTTTATTTTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTGCTTCCCAATCTAAAATTTTTCGAGCCTTTAGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GGTTTTTCGGTCTTTTCCCATTTTTTGTTTTTGCCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATTTTTTCAATGTGTTAAATTGGTTTAATAGATTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTGGTATATTCTCCACCCAGTCTCTCCCCCAGCTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGACATAGAATAACACTGCAAAAAAACATTCCCATAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATTGTCGCTCTCAAAGATGTAACCCACGTTATACG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAATCAACTAAAACTCCAATCTCTCTACCTCTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CATCAATAAATCTAATACACCTTTAAAAAATTCCAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCGTCAATGATTCTTTTGATTTTTCCTTCTCCTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAATTTTCATTCTAAACCCTCCTTTTCTGTTTTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAAAACTCCAAGCGTGCTGCCTTGTAACCGTGGTGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACGACTGCAAAATTTCTTCTACATCTTTTTTTGATG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCAAGAACAATATTGTTTGTTGTGTCTTCCTCATGCTCGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACAACGCTCCACTCATCTAAAGCTTCCTTGTCAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATATTTATCTTTATGTTTGTTACTACTACTCTTTC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGGAAGGGCTTTCAAAATTTTTAAAAGGAGGAGAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGCAATAAAAATTTTGCTTCAAAAAGAAGAAAACAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GCCAAACATACAACCATCGCCAATTCATCAATTC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACTTCTGGTTTAACTACATGAGAAACAAAACAAAGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCCATGTGACCAAACTCAGATGCCACCATGCAGTACA
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TGATTAGAACCTTCCTCTTTCCCTCCTTTCTTTCAGA
GTTTGTGGCCTTCCCGTTGGGGATTGAAAC	ATGAAATTTCCCTTATGAAAATAGTTCCGGTAAACA
GTTTGTAGCCTCCCCGTTGGGGATTGAGGA	AGGAGGGGGTTTGTAGCCTTCCCGTTGGGGATTGAGGAGTAAGAATT
GTTTGTTGCCTATCCTTGGAAAATTGAGAA

>NC_015949|4|4|2569259-2571209|CRT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGATAAAAACCACAACCATTGTTTGTATTTTTCCAT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTTCAAAAAGAAGAAAACAGTTAAGTATCGCTGTAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTCTATCTTCTTCAAAACTCCACAATTTGGGTAAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCCCTCCTTAATTTATTTTTCATCCCCAACTTGAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CACAAAATTATAGTTTTGTGCAGTATGAACCCTGC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACTCTCTCTAATTACTAATTAATTTTTTATTTTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTGCTTCCCAATCTAAAATTTTTCGAGCCTTTAGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GGTTTTTCGGTCTTTTCCCATTTTTTGTTTTTGCCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATTTTTTCAATGTGTTAAATTGGTTTAATAGATTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTGGTATATTCTCCACCCAGTCTCTCCCCCAGCTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGACATAGAATAACACTGCAAAAAAACATTCCCATAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATTGTCGCTCTCAAAGATGTAACCCACGTTATACG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAATCAACTAAAACTCCAATCTCTCTACCTCTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CATCAATAAATCTAATACACCTTTAAAAAATTCCAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCGTCAATGATTCTTTTGATTTTTCCTTCTCCTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAATTTTCATTCTAAACCCTCCTTTTCTGTTTTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAAAACTCCAAGCGTGCTGCCTTGTAACCGTGGTGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACGACTGCAAAATTTCTTCTACATCTTTTTTTGATG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCAAGAACAATATTGTTTGTTGTGTCTTCCTCATGCTCGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACAACGCTCCACTCATCTAAAGCTTCCTTGTCAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATATTTATCTTTATGTTTGTTACTACTACTCTTTC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGGAAGGGCTTTCAAAATTTTTAAAAGGAGGAGAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AGCAATAAAAATTTTGCTTCAAAAAGAAGAAAACAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GCCAAACATACAACCATCGCCAATTCATCAATTC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACTTCTGGTTTAACTACATGAGAAACAAAACAAAGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCCATGTGACCAAACTCAGATGCCACCATGCAGTACA
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TGATTAGAACCTTCCTCTTTCCCTCCTTTCTTTCAGA
GTTTGTGGCCTTCCCGTTGGGGATTGAAAC	ATGAAATTTCCCTTATGAAAATAGTTCCGGTAAACA
GTTTGTAGCCTCCCCGTTGGGGATTGAGGA	AGGAGGGGGTTTGTAGCCTTCCCGTTGGGGATTGAGGAGTAAGAATT
GTTTGTTGCCTATCCTTGGAAAATTGAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_014043365.1\|2550738_2551974_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293879
NC_015949.1\|WP_014043369.1\|2557726_2560150_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_015949.1\|WP_014043376.1\|2571683_2572103_+\|YgiT-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|240606
NC_015949.1\|WP_014043379.1\|2575946_2576273_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273806
NC_015949.1\|WP_014043371.1\|2561013_2561898_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_015949.1\|WP_014043367.1\|2556165_2557158_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_015949.1\|WP_013404366.1\|2555896_2556160_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015949.1\|WP_014043383.1\|2580520_2581144_-\|hypothetical-protein	cas6	mkCas0062_cas6_CAS-I:CAS-III	unknown
NC_015949.1\|WP_014043366.1\|2554908_2555907_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|368098
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NC_015949.1\|WP_014043374.1\|2567716_2568892_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043381.1\|2578100_2579951_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043378.1\|2575184_2575841_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NC_015949.1\|WP_014043377.1\|2572267_2572759_-\|DUF3368-domain-containing-protein	unknown	unknown	gnl\|CDD\|225269
NC_015949.1\|WP_014043368.1\|2557199_2557697_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_015949.1\|WP_014043380.1\|2576298_2578095_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|223510
NC_015949.1\|WP_014043370.1\|2560239_2560992_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09692_cas5_CAS-I-B	gnl\|CDD\|187823
NC_015949.1\|WP_013433677.1\|2572769_2573036_-\|UPF0175-family-protein	unknown	unknown	gnl\|CDD\|377095
NC_015949.1\|WP_014043372.1\|2561919_2563983_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_015949.1\|WP_014043382.1\|2580256_2580394_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_014043365.1\|2550738_2551974_-\|hypothetical-protein	gnl\|CDD\|293879	cd16269, GBP_C, Guanylate-binding protein, C-terminal domain. Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines.	0.00457754
NC_015949.1\|WP_014043369.1\|2557726_2560150_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.9376e-46
NC_015949.1\|WP_014043376.1\|2571683_2572103_+\|YgiT-type-zinc-finger-protein	gnl\|CDD\|240606	cd12870, MqsA, antitoxin MqsA for MqsR toxin. This family includes domains similar to the antitoxin MqsA that binds motility quorum-sensing regulator MqsR, a toxin that is highly upregulated in persisters (dormant cells found in biofilms that are a source of antibiotic resistance), thus forming a unique toxin:antitoxin (TA) pair. MqsA neutralizes MsqR toxicity. It binds its own promoter as well as those of genes important for E. coli physiology, such as mcbR and spy. It also binds zinc and has been shown to coordinate DNA via its C-terminal domain. This family also includes the B. subtilis YokU protein, which is functionally uncharacterized.	3.86959e-07
NC_015949.1\|WP_014043379.1\|2575946_2576273_+\|hypothetical-protein	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.4693e-08
NC_015949.1\|WP_014043367.1\|2556165_2557158_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	9.9555e-159
NC_015949.1\|WP_013404366.1\|2555896_2556160_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.57908e-32
NC_015949.1\|WP_014043366.1\|2554908_2555907_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|368098	pfam04754, Transposase_31, Putative transposase, YhgA-like. This family of putative transposases includes the YhgA sequence from Escherichia coli and several prokaryotic homologs.	8.38843e-18
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	4.63196e-24
NC_015949.1\|WP_014043371.1\|2561013_2561898_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	3.0147e-70
NC_015949.1\|WP_014043378.1\|2575184_2575841_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.19636e-07
NC_015949.1\|WP_014043377.1\|2572267_2572759_-\|DUF3368-domain-containing-protein	gnl\|CDD\|225269	COG2405, COG2405, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	1.90428e-34
NC_015949.1\|WP_014043368.1\|2557199_2557697_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.42795e-72
NC_015949.1\|WP_014043380.1\|2576298_2578095_-\|ATP-binding-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	2.70685e-17
NC_015949.1\|WP_014043370.1\|2560239_2560992_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187823	cd09692, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.24356e-26
NC_015949.1\|WP_013433677.1\|2572769_2573036_-\|UPF0175-family-protein	gnl\|CDD\|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	6.25062e-14
NC_015949.1\|WP_014043372.1\|2561919_2563983_-\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	7.76302e-142

>NC_015949.1|WP_014043374.1|2567716_2568892_-|hypothetical-protein
MRKYNKTFITVVVFCSILMIQIIPVALGASSSYLNVKLSDYTAYIDGVKLPVYSVNGNLMINLNHLNYYGFKVSSSDTTVLCYRDASRQITGIPKSQWATKYNVVSIKPRNKCYLNGKEIPVLYLNNQPFIFLNELYEDNIVKVNGKNVNITLGIVDGLQKTQKSLEQMDYMIKILNLDTDITEYSVAYIYYDPITKLTMVNFADNVLDIFEEKAEKNYTLLQMYVVLCKHYPEGSYTQELYINEDWKKWSDYYIKQDYINKLKFIYSLYQKANGNSPVYVIGAEVKEASIGYPQAELKIFNFSAMPIDAVEVSFKCYNLFDQPALNESQSNQFVGIKQKISIPAFDSSVVSFDLTRYPSAGKIKNVLIRKVHFIDNKIWINPATGNSKKL
>NC_015949.1|WP_014043372.1|2561919_2563983_-|TIGR02556-family-CRISPR-associated-protein
MIEEIVEIGDILIGVSSGNEAYLSALIEEIEVPSGNEKNFVAKINFSTKEKIITIDCAEEVKDSTAKDYVYVGSAEGSNSPQWFASTKSFAYFLTETIPNLAERSIPVVSDICKKILDDYFVNIKEYLLSSAELTEEEKMLLNQRIEKKYMYFLNTDHVMVNDNKKLTERPISQIYKELIRKGKSTDKVFKQLRDAFTKECTDGLKKLTELKPQQIGLYVLCVDGKPLTSYPEYVEAVVAYKRQVKKGAEKTGEKQKEGNICYICLGTDGLSFEGLKKPKFKYFTTNQNIFASYLDQKNYAKNITVCEKCLSKLVAGDIFLRNKLKTQFGSFDVYVLPTFVYTSAKLTKNYLEDLTLNITNSLNTAWNYNRLEKLRDDISNFLSFFDQNHYFLLNLIFYREAQAGTKIMKFIPDINPSIFDKIYNAASKVFSQYIDIIGNDPSFRISLESIYYSVPIRLKNRNESTEAQRLLNIYDAIFSGKRIARDFLIENFIKAVGVVVYGKEGYNLSKFIGNDIALMVIRMVFVMKFLEFLDCLEVERGMDVSQLNLSDDLKSYIQQMNYDEPKTALFLLGVLIGEIGAKQYLATKDRQDDSAGHKPILNKINYNGIDRPKLIRLCSDVHNKLRQEKLLPYTEMIFAEMKRLLDKHIDSWKLDKYETLFYILSGYAYKTQKVILNASNSQETSN
>NC_015949.1|WP_014043371.1|2561013_2561898_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MEKKIIDKNSEILFTYDAKLCNPNGDPDEENRPRMDWEKEINLVSDLRVKRYIRDYLDDKGIPIYVRKIDGKSVKPEEVIKSVGEDIDELETFIDIRLFGATIPIKGETRTYIGPVQFNWGYSLNKVELLEASITSHFASREKNQQGAIGKDYRVKYSFIAFSGIVSAKRAKITRLTEDDVRFLDRAMKEAIPLQATRSKIGQYPRLYMRVEYVDDKTLLGDLRDYIRLIEVVEKPRKIEDVQLDITSLVEFLEKNKDEISKIYYFKHPDLCLVCGGNAVDFKDAFGTFELEEV
>NC_015949.1|WP_014043370.1|2560239_2560992_-|type-I-B-CRISPR-associated-protein-Cas5
MKFLVFDLKGKFAHFRKFYTNSSSLSYLVPPRTVVEGVVAAILGFERDSYYEELSAENLLIAVQKIERTYKIVQTVNYIKATSVNELKNPNTHTQVPLELLAGYNGFVGFRVFVMPRDEKMYSQLKSKLESGRAEFPIYFGSAPFAAKTEFVGEFEAYRWEDSSARILTVLDTGLMKSLNLSLESSAGLALMKDRMPCDFDKDRFATKVKTYINDENLNPIWVDLDSSAQDKVYFIKEFSSDKELCISLM
>NC_015949.1|WP_014043369.1|2557726_2560150_-|CRISPR-associated-helicase/endonuclease-Cas3
MEYYSHKNPDKLLYDHLLEVYHYAMEANVELKSWEKEALQVICLCHDFGKFTTFFQSHLNGVLNKYSQHGFISALFGVFCWMQKKGLWLQQMKNQISEDEVVSLLIYACILHHHGDVKDISKNLPEKFAGDFKADINLVQKIDDAYVQIEDLRCNAEDIKPLLEKIGLGSEFEKFLAQQRGFIEDILRYLKRIEYGIRFIGVMPQALKDGTELYFIQQKLYSLLIWADKMSAANYKVLSPCYASSDRLIVARNKVIRPTADKNLQRIRQSVFEAVLSNIEKNKEKDIFSITTPTGTGKTLAGVFAAVKLKELLKKSGRIIYALPFTSIIDQNYDVVKNLFEAIEDFEKNRDRYLLKHHHLTDGEYRGKEEALKEITDEITVYEKVASECFIENWTSGFVVTTFVQLLETLISNRNRMLKKFHAFYDSILILDEIQAIEVDLLPLVEEVLRKLSKLFKCKIILMTATKPLIFEDACELAGFCDYSIFNRTKLVYHHSDLKVAEFVDFFLEQVYEDEKSFLIVANTINQSLQIYNGIKNNLKDKEVIYLSANLVPRDRKEVIKKIEEALESGRKPIVVSTQVIEAGVDIDFDCVIRDIAPIDSIIQCAGRCNRHNQKSQGKVLVVNIKDDSGRSFAKRVYGNTAIEISNMLLLQHPEVEEKDYGMLIDNYFRMVKENKSFKKSEEFLRSIRLLKFDSILEKEELTISRFSLIQQRGGYVSVVIRSNEEIEDAYQSYINSFSIKDYYKRREIYLELKNILFEHTISVPSKYVQILAEEKGILSLPPTSCERYYNPETGFVYDPNDNVIFA
>NC_015949.1|WP_014043368.1|2557199_2557697_-|CRISPR-associated-protein-Cas4
MDVYMTGVYIWYYNICKRQVWLMAHGVLPDENDDNIVLGRFLHEYYYKKDQKEIKFGNAVFDILYQDKDEIVIGETKKSSRFKEASRYQLLFYIKLLKEAGISAKGVLFYPEERKKEEVELTVEDEEKLQKMIAEIETIIEKDSPPPAAYCRYCPKCAYREYCFA
>NC_015949.1|WP_014043367.1|2556165_2557158_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKDLYVFNSGFLRRKDNTIMFETDEGKKYFPVEEIESVFIFGEVDINKRFLEFMTEKNICVHFFNRYEYYVGTYYPREHYNSGIVILKQVEFYNDYNKRMTIARSIVEGAVLNMLVVLRYYNSRGNILKDEIETIERMRHNINSCDDVNTLMALEGNIREIYYRCFNKILDDENFTFVRRSKNPPLDRINALISFGNSLLYATTLGEIYQTQLDPRIGYLHSTNQRKFSLNLDISEIFKPIIVDRVIFSLVNKKVLSEKHFERELNGIILNDQGKKLFVSEYNQKLYSTITHPKLNCQVSYKRLIRMEAYKLQKLFLENIEYKPFVARW
>NC_015949.1|WP_013404366.1|2555896_2556160_-|CRISPR-associated-endonuclease-Cas2
MFVILVYDVNEKRVAKALKKCRQYLTWVQNSVFEGNISEGTLRRLILELERILDLSEDSVIIYKFQNTWYSERQIIGIEKNPVDFMT
>NC_015949.1|WP_014043366.1|2554908_2555907_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MCEKLPPKEHDTTFKFLFADKEEILLLVKDILHYTWADNIEEDTIELVKTNYVTQQFSQVEADVVAKAKLKDKEVYFYILIENQSKVKREMQQKILKYMISLWAEEIRKGVQILPAIIPIVVYNGIGERWNVSTDLMEAFDVFKDDVFRYRVVDIIELDVKKLLEREEDVLTPIVFYLEQAREDRSELIGRLLEVEKNLKKLSKKNVDRFLEWSYHIIRPRLAEDQKSEFDRIAKRVKQEGVEAMGEFISNVARLLDEAKTKDFLAGKLEGKLEGKIEGKIEGKLEGKLEATIEFAKRLIQKGFSDEEVAELTELQIEKVKELRKSFKNTMS
>NC_015949.1|WP_014043365.1|2550738_2551974_-|hypothetical-protein
MHSAEHKEENTLTKRPDFPKDATPKQNTSYKLLLRKELKNVQNFGKFFFELDVLTIAGVSRCLKDGNNFESVKRFVKERLERYQFDANEIHLIIDYLNADNFSFKLMVNEGIERIEKDRFIIEAFVKCYIARYFANRLFEGKKGLMKEIEKDFSEMCGQENLYFFGELKKWIISYDIWPKTAQQYAEIASSFKDEIEDVYSKVFSEVQKRRLIKIGKKKDHQEESQNIAEKAVKSQAEAVAGTRENEEFRKLKEKLENYELMVNMLQEQIEELREINSELQKEREMLLQERQQLPEKILIKLFNDLNSPQFGNLLDKIYVYANDLEPVDSSTAQEIFTNIISVLSLYNIVGHLSKEEYKSTISIKKEEIGSIYRCDRPAQSDKQVYEAQILYPKWTYNQKTVANKFVRIKS
>NC_015949.1|WP_014043376.1|2571683_2572103_+|YgiT-type-zinc-finger-protein
MGKKCFFCGAEMKKEITSVESGWGEYTFKIEGVHAYVCHECGEKIFEPKEAEMILELGRALSFLPNEERPAPNEVLDINGIHDFLKILSSSIFSLITNKDIKLQRKKINGFFKQKIYSKFCTTGLVFIITTTMPWDYDY
>NC_015949.1|WP_014043377.1|2572267_2572759_-|DUF3368-domain-containing-protein
MIVVSNTTPIIVFAKLERLDILENLFGTIYISPSVYQELTYSSKFEEEKGRIMNAAFLKIKELRNEFAAEILQRTQAIDKGESETIILAKESNADLLIMDEKKGRSVAKLLGLRLTGSLGILLKAKEVGVVSQIEPLIKKLIKENIRISPQLVEEILKQAKEK
>NC_015949.1|WP_013433677.1|2572769_2573036_-|UPF0175-family-protein
MEGIKIEIELPKEILNYISLNEITNDKVLKELIIYKLIKDEKISFGKGAEILGMSKIELIEELSEYGVNYFDQPIEEVIEDKNAIDKM
>NC_015949.1|WP_014043378.1|2575184_2575841_+|MFS-transporter
MVLLTIAISLPHSVLTVLLLAKGITLSQIMIIQAGYSFAVLISEYPSGLIADMYSKKMVFICSKLFLLLMFCLVISMNNFWMLLIAWFMYGISSALDTGTIEAEIINQLKLSGMQIDKFISNSNRLNFIALLIGSSIGSFIYYAIGIKLYWISIILTIVSTICVGIFYKGETSEKTKISLFEIFKRMLVQSKDGIKEMRKKESLKLMIALELALCYVC
>NC_015949.1|WP_014043379.1|2575946_2576273_+|hypothetical-protein
MKLAEEQKSEYDGIAKRVKQEGVEAMGEFISNVARLLDEAKTKYFLAGKLEGKLEGKIEGKLEGKLEATIEFAKRLIKKGFSDEEVAELTELQIEKVKELKKVHGKLT
>NC_015949.1|WP_014043380.1|2576298_2578095_-|ATP-binding-protein
MFNTEIVGRMMKYDSDIYSRYRAEIWFDYTKKAMNEIKEGALLAVQNFSSTSDKIRYCILEITSVIPLHYGLDNDLSGYPGFLTEAAENIYRDWEEQEEEPLDDATKIRCLAIPTNFEIIIDKDQKVSIGIESNLPMVGAEAFLLDEELTNRILNYDIDKSGDVIEIGHLIRDENVKILLKVEELLRVHFGVFGFTGAGKSNLLSTLVRKILTESNLPVKIVIFDLMGEYSTLLVDLLVKLNNSMIVGIGEKTFVGSLISLMKADRSLPEYKDLLKKATIDVVNSSLYPKGLVSHKDLFKKAFFRILQSRKVKIWQSGDIAVADFAKMYERTLLKGNLGKSEALIKKLYEQLLRKTNPLNATVCLALIQYIENKYLSDEKLGSIARSNLELFVNELKKKYEELKEFGFSNENVIDQKKLIEILNSPDDKALVIFQSHDPDELRNLAYQIGMAIFEDRRRSGKIDPVVSFIFDEADEFIPQDAKDSYERSSEVVMHLARRGRKFGLGIGIATQRITYLNTNIMAQPHTYFVSKLPRKSDQERITDAFGISEDMFKQTFKFKKGCWLLVSYDAIGLEAVPLPIYVQNANDAVLEFLKTLQ
>NC_015949.1|WP_014043381.1|2578100_2579951_-|hypothetical-protein
MSKLSQIYGYWKNSIKASMKRYDENMERSLKHLQNFYNMVLKDYIIDWSRYFESQPFRHSLRQKIENFFGKNEINFVAIDGTCVKDEGSDFITFFAGAYGARGKIIIKHEGEKIKYERWDFARDVTMVAQIPVFPYEIEFVASSPELSQMQFYSDKDIQEILNLHTSLMKLAEIYLAYHVVSSSTVDIPQIILLDLAPSTLLRVPYVNYKSTNYLGYKYLNDTIKLSDVIVALSHPYNSLLGVPSRKKYRRYALLLSKLDEVCSQNHKNYFTYKELTEICHLSIEDIKEIVRFLDATGVVEDDEAAGIKLFVNLSQRWSYLVSFFDYICNQIFIRKNPTALEFSNFSEESNIKKLISHDDINFLISIGIRALIEKCWEKNVFLIGIVKDSKSRYFCRNFLNVLSSQNMLGDGKENVDIKNFQIAMSDRLVFENCAALSTELCAPWSSVEFDSAFATLFVDRNNSVTGVKGHIVADDRIFAKSIAQFYLQRSKKQCKMGHAIFVERLLHPSLDRQFLDLVLLENSKLGRLSPFIHLDKKVINWGQAMNIYFLDVLTRNHFPEVIGYPEPLHKADRGAKTLLRFAKGVIHSSQQLYRKDPLNMTFRKFRDKLEFEDEE
>NC_015949.1|WP_014043382.1|2580256_2580394_-|hypothetical-protein
MSLSALLGASIMMHGLVQGLKVFAVVVVLGFVIKGLWQGFKKELA
>NC_015949.1|WP_014043383.1|2580520_2581144_-|hypothetical-protein
MMGCDEKVAKYFTFHFWAREDGVFLPSSYYSKVYEVLKSLLATEQFTISPIKTKNKKEVEDGVWVFEDFRIYLATPFLELFTQNILKIYETLNGLFEGIYLKKISCRSQQPKASGILLSGVFAQKDGVCLEYDRQPEIFSDGLRRQLLNIYYQRFGAYPEDQRFFFVIKDGLKKQHLIRSRIEYFGRYEIFASSELLDMFCQMFCVK
>NC_015949.1|WP_014043384.1|2581140_2582325_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MAHEPFESRTYEIEVLTPTIIGGQDKIQSFEFVKDGDYLYFINFDRLLEENLFKESFIDELSRGLSTGDRDFNIKDVLARYNIDFKNSSKYRLKLEGVKRISKEVVPFVKSAGRFYIPGSSLKGAIRSFVTKALNRNFIQLYENDLSSAYQKTLNSADRRNSVDPKYVCKDAEEKIFATPYESPFKHLKISDSDFVSSENAGVYEIKVMNICGGQVKWFAGRSNEDVPDRAVSIIAEGIKPGAKLIGSIKVEKDFVEGNQVVRGIKEKIGVNASATSPTEFLADVLKVVSKDYIQREINFYTRYKQAQIVSEYQKLLNVLNSLDKNQFLIQIGFSTGYLSKTVGIFFNKNHFEKLAKVDRQSKIYPELFPKTRRLVFKNGQVWTVPGWIKVTIK

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Crispr_ID: NC_015949_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_5

2573557-2574780

TypeIII

Consensus_repeat	Method
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	PILER-CR
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CRISPRCasFinder
GTTTGTAGCCTNCCCGTTGGGGATTGAAAC	CRT

18 spacers

cas8b1,cas7b,cas5,cas3,cas4,cas1,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11

The CRISPR arrays of NC_015949_5

>merge|NC_015949|5|2573557-2574780|PILER-CR,CRISPRCasFinder,CRT
GTTTGTAGCCTTCCCGTTGGGGATTGAAACGGGTTTGAGACAGGTTTTTAGATTAATCTTTAAATAGTTTGTAGCCTTCCCGTTGGGGATTGAAACCTTCTCATCAAATCACCGCCTTCCTCTAACGAAAACGTTTGTAGCCTTCCCGTTGGGGATTGAAACACGGCACAAGGACAGCTGAAAACCTGACCATCCCCATGGTTTGTAGCCTTCCCGTTGGGGATTGAAACTTTCATCAATAAAAACATCCACTATAACATTAATAGCGTTTGTAGCCTTCCCGTTGGGGATTGAAACTCTTTTAAATCTTTTTTTGTTTTTACCATTTTTAGTTTGTAGCCTTCCCGTTGGGGATTGAAACACTCTATAATATAATCTCTAATTGCATCTCTTAAACTGTTTGTAGCCTTCCCGTTGGGGATTGAAACTCGCTTGTGTAGTGTCCTGAATCTTATCTTTTAGCTGTGTTTGTAGCCTTCCCGTTGGGGATTGAAACTCTTTTAAATCTTTTTTTTCTCTTCTCGTTTTTAGTTTGTAGCCTTCCCGTTGGGGATTGAAACTCTTATCTTGGCTGGATGATACAAAGCAAAGCTAATTGTTTGTAGCCTTCCCGTTGGGGATTGAAACGTAGCCATGTGGGAGATGGCGCATGTTTCGGTTTTTGGGTTTGTAGCCTTCCCGTTGGGGATTGAAACTCGGCACCTAATAAATTCAATTAAGCGATGTCGCACAGTTTGTAGCCTTCCCGTTGGGGATTGAAACCAAGATTTTGCTTGCAATTGGCTTTAAGTGTTCCGTTTGTAGCCTCCCCGTTGGGGATTGAAACTATCATTGAAGATATAATTTAGCACTCTAGCGCTGAGTTTGTAGCCTTCCCGTTGGGGATTGAAACGATGAGATAGCTGAAATGATACAAAGAGCTGGATTAGTTTGTAGCCTCCCCGTTGGGGATTGAAACGCAATAATAAGTCTCAACACCTTTGGCTTTTGTGTGTTTGTAGCCTCCCCGTTGGGGATTGAAACCTAAGTAGGGGGTGGTGTTTTGACCACTCCCTAAAAAGGTTTGTAGCCTCCCCGTTGGGGATTGAAACTCAATTTTTAAATTCTTGAAATCTTCATTGTCTAACAGGTTTGTAGCCTCCCCGTTGGGGATTGAAACGAAACAAGCTCCTGAGGCAGCTGCAACCCTTCATCGTTTGTAGCCTCCCCGTTGGGGATTGAGGT

>NC_015949|5|5|2573557-2574715|PILER-CR
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GGGTTTGAGACAGGTTTTTAGATTAATCTTTAAATA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CTTCTCATCAAATCACCGCCTTCCTCTAACGAAAAC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACGGCACAAGGACAGCTGAAAACCTGACCATCCCCATG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTTCATCAATAAAAACATCCACTATAACATTAATAGC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCTTTTAAATCTTTTTTTGTTTTTACCATTTTTA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACTCTATAATATAATCTCTAATTGCATCTCTTAAACT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCGCTTGTGTAGTGTCCTGAATCTTATCTTTTAGCTGT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCTTTTAAATCTTTTTTTTCTCTTCTCGTTTTTA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCTTATCTTGGCTGGATGATACAAAGCAAAGCTAATT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GTAGCCATGTGGGAGATGGCGCATGTTTCGGTTTTTGG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCGGCACCTAATAAATTCAATTAAGCGATGTCGCACA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CAAGATTTTGCTTGCAATTGGCTTTAAGTGTTCC
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TATCATTGAAGATATAATTTAGCACTCTAGCGCTGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GATGAGATAGCTGAAATGATACAAAGAGCTGGATTA
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	GCAATAATAAGTCTCAACACCTTTGGCTTTTGTGT
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	CTAAGTAGGGGGTGGTGTTTTGACCACTCCCTAAAAAG
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TCAATTTTTAAATTCTTGAAATCTTCATTGTCTAACAG
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC

>NC_015949|5|5|2573557-2574780|CRISPRCasFinder
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GGGTTTGAGACAGGTTTTTAGATTAATCTTTAAATA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CTTCTCATCAAATCACCGCCTTCCTCTAACGAAAAC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACGGCACAAGGACAGCTGAAAACCTGACCATCCCCATG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTTCATCAATAAAAACATCCACTATAACATTAATAGC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCTTTTAAATCTTTTTTTGTTTTTACCATTTTTA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACTCTATAATATAATCTCTAATTGCATCTCTTAAACT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCGCTTGTGTAGTGTCCTGAATCTTATCTTTTAGCTGT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCTTTTAAATCTTTTTTTTCTCTTCTCGTTTTTA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCTTATCTTGGCTGGATGATACAAAGCAAAGCTAATT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GTAGCCATGTGGGAGATGGCGCATGTTTCGGTTTTTGG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCGGCACCTAATAAATTCAATTAAGCGATGTCGCACA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CAAGATTTTGCTTGCAATTGGCTTTAAGTGTTCC
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TATCATTGAAGATATAATTTAGCACTCTAGCGCTGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GATGAGATAGCTGAAATGATACAAAGAGCTGGATTA
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	GCAATAATAAGTCTCAACACCTTTGGCTTTTGTGT
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	CTAAGTAGGGGGTGGTGTTTTGACCACTCCCTAAAAAG
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TCAATTTTTAAATTCTTGAAATCTTCATTGTCTAACAG
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	GAAACAAGCTCCTGAGGCAGCTGCAACCCTTCATC
GTTTGTAGCCTCCCCGTTGGGGATTGAGGT

>NC_015949|5|5|2573557-2574780|CRT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GGGTTTGAGACAGGTTTTTAGATTAATCTTTAAATA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CTTCTCATCAAATCACCGCCTTCCTCTAACGAAAAC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACGGCACAAGGACAGCTGAAAACCTGACCATCCCCATG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TTTCATCAATAAAAACATCCACTATAACATTAATAGC
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCTTTTAAATCTTTTTTTGTTTTTACCATTTTTA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	ACTCTATAATATAATCTCTAATTGCATCTCTTAAACT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCGCTTGTGTAGTGTCCTGAATCTTATCTTTTAGCTGT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCTTTTAAATCTTTTTTTTCTCTTCTCGTTTTTA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCTTATCTTGGCTGGATGATACAAAGCAAAGCTAATT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GTAGCCATGTGGGAGATGGCGCATGTTTCGGTTTTTGG
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	TCGGCACCTAATAAATTCAATTAAGCGATGTCGCACA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CAAGATTTTGCTTGCAATTGGCTTTAAGTGTTCC
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TATCATTGAAGATATAATTTAGCACTCTAGCGCTGA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	GATGAGATAGCTGAAATGATACAAAGAGCTGGATTA
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	GCAATAATAAGTCTCAACACCTTTGGCTTTTGTGT
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	CTAAGTAGGGGGTGGTGTTTTGACCACTCCCTAAAAAG
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TCAATTTTTAAATTCTTGAAATCTTCATTGTCTAACAG
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	GAAACAAGCTCCTGAGGCAGCTGCAACCCTTCATC
GTTTGTAGCCTCCCCGTTGGGGATTGAGGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_014043387.1\|2584207_2584618_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NC_015949.1\|WP_014043369.1\|2557726_2560150_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_015949.1\|WP_014043376.1\|2571683_2572103_+\|YgiT-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|240606
NC_015949.1\|WP_014043379.1\|2575946_2576273_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273806
NC_015949.1\|WP_014043371.1\|2561013_2561898_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_015949.1\|WP_014043367.1\|2556165_2557158_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_015949.1\|WP_014043372.1\|2561919_2563983_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_015949.1\|WP_014043383.1\|2580520_2581144_-\|hypothetical-protein	cas6	mkCas0062_cas6_CAS-I:CAS-III	unknown
NC_015949.1\|WP_014043386.1\|2583352_2584180_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_015949.1\|WP_014043385.1\|2582314_2583325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|273866
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NC_015949.1\|WP_014043374.1\|2567716_2568892_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043381.1\|2578100_2579951_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043378.1\|2575184_2575841_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NC_015949.1\|WP_014043377.1\|2572267_2572759_-\|DUF3368-domain-containing-protein	unknown	unknown	gnl\|CDD\|225269
NC_015949.1\|WP_014043368.1\|2557199_2557697_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_015949.1\|WP_014043380.1\|2576298_2578095_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|223510
NC_015949.1\|WP_014043370.1\|2560239_2560992_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09692_cas5_CAS-I-B	gnl\|CDD\|187823
NC_015949.1\|WP_013433677.1\|2572769_2573036_-\|UPF0175-family-protein	unknown	unknown	gnl\|CDD\|377095
NC_015949.1\|WP_014043382.1\|2580256_2580394_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015949.1\|WP_014043371.1\|2561013_2561898_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	2.6e-67	221.9	0.5
NC_015949.1\|WP_014043369.1\|2557726_2560150_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	8.1e-58	191.0	15.4
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	5.2e-34	112.7	7.0
NC_015949.1\|WP_014043385.1\|2582314_2583325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	3.1e-60	198.7	2.5
NC_015949.1\|WP_014043368.1\|2557199_2557697_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	4.7e-53	174.4	1.8
NC_015949.1\|WP_014043386.1\|2583352_2584180_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	6.5e-68	223.4	0.4
NC_015949.1\|WP_014043367.1\|2556165_2557158_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	1.8e-134	442.6	13.7
NC_015949.1\|WP_014043387.1\|2584207_2584618_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	1.1e-36	120.6	0.5
NC_015949.1\|WP_014043372.1\|2561919_2563983_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	pfam09484_cas8b1_CAS-I-B	1e-186	616.8	31.0
NC_015949.1\|WP_014043383.1\|2580520_2581144_-\|hypothetical-protein	cas6	mkCas0062_cas6_CAS-I:CAS-III	3.1e-95	312.2	3.0
NC_015949.1\|WP_014043370.1\|2560239_2560992_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09692_cas5_CAS-I-B	4.7e-34	112.3	0.1

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_014043387.1\|2584207_2584618_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	1.09819e-32
NC_015949.1\|WP_014043369.1\|2557726_2560150_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.9376e-46
NC_015949.1\|WP_014043376.1\|2571683_2572103_+\|YgiT-type-zinc-finger-protein	gnl\|CDD\|240606	cd12870, MqsA, antitoxin MqsA for MqsR toxin. This family includes domains similar to the antitoxin MqsA that binds motility quorum-sensing regulator MqsR, a toxin that is highly upregulated in persisters (dormant cells found in biofilms that are a source of antibiotic resistance), thus forming a unique toxin:antitoxin (TA) pair. MqsA neutralizes MsqR toxicity. It binds its own promoter as well as those of genes important for E. coli physiology, such as mcbR and spy. It also binds zinc and has been shown to coordinate DNA via its C-terminal domain. This family also includes the B. subtilis YokU protein, which is functionally uncharacterized.	3.86959e-07
NC_015949.1\|WP_014043379.1\|2575946_2576273_+\|hypothetical-protein	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.4693e-08
NC_015949.1\|WP_014043386.1\|2583352_2584180_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	6.51835e-76
NC_015949.1\|WP_014043367.1\|2556165_2557158_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	9.9555e-159
NC_015949.1\|WP_014043372.1\|2561919_2563983_-\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	7.76302e-142
NC_015949.1\|WP_014043385.1\|2582314_2583325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	1.20453e-51
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	4.63196e-24
NC_015949.1\|WP_014043371.1\|2561013_2561898_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	3.0147e-70
NC_015949.1\|WP_014043378.1\|2575184_2575841_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.19636e-07
NC_015949.1\|WP_014043377.1\|2572267_2572759_-\|DUF3368-domain-containing-protein	gnl\|CDD\|225269	COG2405, COG2405, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	1.90428e-34
NC_015949.1\|WP_014043368.1\|2557199_2557697_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.42795e-72
NC_015949.1\|WP_014043380.1\|2576298_2578095_-\|ATP-binding-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	2.70685e-17
NC_015949.1\|WP_014043370.1\|2560239_2560992_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187823	cd09692, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.24356e-26
NC_015949.1\|WP_013433677.1\|2572769_2573036_-\|UPF0175-family-protein	gnl\|CDD\|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	6.25062e-14

>NC_015949.1|WP_013433677.1|2572769_2573036_-|UPF0175-family-protein
MEGIKIEIELPKEILNYISLNEITNDKVLKELIIYKLIKDEKISFGKGAEILGMSKIELIEELSEYGVNYFDQPIEEVIEDKNAIDKM
>NC_015949.1|WP_014043377.1|2572267_2572759_-|DUF3368-domain-containing-protein
MIVVSNTTPIIVFAKLERLDILENLFGTIYISPSVYQELTYSSKFEEEKGRIMNAAFLKIKELRNEFAAEILQRTQAIDKGESETIILAKESNADLLIMDEKKGRSVAKLLGLRLTGSLGILLKAKEVGVVSQIEPLIKKLIKENIRISPQLVEEILKQAKEK
>NC_015949.1|WP_014043376.1|2571683_2572103_+|YgiT-type-zinc-finger-protein
MGKKCFFCGAEMKKEITSVESGWGEYTFKIEGVHAYVCHECGEKIFEPKEAEMILELGRALSFLPNEERPAPNEVLDINGIHDFLKILSSSIFSLITNKDIKLQRKKINGFFKQKIYSKFCTTGLVFIITTTMPWDYDY
>NC_015949.1|WP_014043374.1|2567716_2568892_-|hypothetical-protein
MRKYNKTFITVVVFCSILMIQIIPVALGASSSYLNVKLSDYTAYIDGVKLPVYSVNGNLMINLNHLNYYGFKVSSSDTTVLCYRDASRQITGIPKSQWATKYNVVSIKPRNKCYLNGKEIPVLYLNNQPFIFLNELYEDNIVKVNGKNVNITLGIVDGLQKTQKSLEQMDYMIKILNLDTDITEYSVAYIYYDPITKLTMVNFADNVLDIFEEKAEKNYTLLQMYVVLCKHYPEGSYTQELYINEDWKKWSDYYIKQDYINKLKFIYSLYQKANGNSPVYVIGAEVKEASIGYPQAELKIFNFSAMPIDAVEVSFKCYNLFDQPALNESQSNQFVGIKQKISIPAFDSSVVSFDLTRYPSAGKIKNVLIRKVHFIDNKIWINPATGNSKKL
>NC_015949.1|WP_014043372.1|2561919_2563983_-|TIGR02556-family-CRISPR-associated-protein
MIEEIVEIGDILIGVSSGNEAYLSALIEEIEVPSGNEKNFVAKINFSTKEKIITIDCAEEVKDSTAKDYVYVGSAEGSNSPQWFASTKSFAYFLTETIPNLAERSIPVVSDICKKILDDYFVNIKEYLLSSAELTEEEKMLLNQRIEKKYMYFLNTDHVMVNDNKKLTERPISQIYKELIRKGKSTDKVFKQLRDAFTKECTDGLKKLTELKPQQIGLYVLCVDGKPLTSYPEYVEAVVAYKRQVKKGAEKTGEKQKEGNICYICLGTDGLSFEGLKKPKFKYFTTNQNIFASYLDQKNYAKNITVCEKCLSKLVAGDIFLRNKLKTQFGSFDVYVLPTFVYTSAKLTKNYLEDLTLNITNSLNTAWNYNRLEKLRDDISNFLSFFDQNHYFLLNLIFYREAQAGTKIMKFIPDINPSIFDKIYNAASKVFSQYIDIIGNDPSFRISLESIYYSVPIRLKNRNESTEAQRLLNIYDAIFSGKRIARDFLIENFIKAVGVVVYGKEGYNLSKFIGNDIALMVIRMVFVMKFLEFLDCLEVERGMDVSQLNLSDDLKSYIQQMNYDEPKTALFLLGVLIGEIGAKQYLATKDRQDDSAGHKPILNKINYNGIDRPKLIRLCSDVHNKLRQEKLLPYTEMIFAEMKRLLDKHIDSWKLDKYETLFYILSGYAYKTQKVILNASNSQETSN
>NC_015949.1|WP_014043371.1|2561013_2561898_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MEKKIIDKNSEILFTYDAKLCNPNGDPDEENRPRMDWEKEINLVSDLRVKRYIRDYLDDKGIPIYVRKIDGKSVKPEEVIKSVGEDIDELETFIDIRLFGATIPIKGETRTYIGPVQFNWGYSLNKVELLEASITSHFASREKNQQGAIGKDYRVKYSFIAFSGIVSAKRAKITRLTEDDVRFLDRAMKEAIPLQATRSKIGQYPRLYMRVEYVDDKTLLGDLRDYIRLIEVVEKPRKIEDVQLDITSLVEFLEKNKDEISKIYYFKHPDLCLVCGGNAVDFKDAFGTFELEEV
>NC_015949.1|WP_014043370.1|2560239_2560992_-|type-I-B-CRISPR-associated-protein-Cas5
MKFLVFDLKGKFAHFRKFYTNSSSLSYLVPPRTVVEGVVAAILGFERDSYYEELSAENLLIAVQKIERTYKIVQTVNYIKATSVNELKNPNTHTQVPLELLAGYNGFVGFRVFVMPRDEKMYSQLKSKLESGRAEFPIYFGSAPFAAKTEFVGEFEAYRWEDSSARILTVLDTGLMKSLNLSLESSAGLALMKDRMPCDFDKDRFATKVKTYINDENLNPIWVDLDSSAQDKVYFIKEFSSDKELCISLM
>NC_015949.1|WP_014043369.1|2557726_2560150_-|CRISPR-associated-helicase/endonuclease-Cas3
MEYYSHKNPDKLLYDHLLEVYHYAMEANVELKSWEKEALQVICLCHDFGKFTTFFQSHLNGVLNKYSQHGFISALFGVFCWMQKKGLWLQQMKNQISEDEVVSLLIYACILHHHGDVKDISKNLPEKFAGDFKADINLVQKIDDAYVQIEDLRCNAEDIKPLLEKIGLGSEFEKFLAQQRGFIEDILRYLKRIEYGIRFIGVMPQALKDGTELYFIQQKLYSLLIWADKMSAANYKVLSPCYASSDRLIVARNKVIRPTADKNLQRIRQSVFEAVLSNIEKNKEKDIFSITTPTGTGKTLAGVFAAVKLKELLKKSGRIIYALPFTSIIDQNYDVVKNLFEAIEDFEKNRDRYLLKHHHLTDGEYRGKEEALKEITDEITVYEKVASECFIENWTSGFVVTTFVQLLETLISNRNRMLKKFHAFYDSILILDEIQAIEVDLLPLVEEVLRKLSKLFKCKIILMTATKPLIFEDACELAGFCDYSIFNRTKLVYHHSDLKVAEFVDFFLEQVYEDEKSFLIVANTINQSLQIYNGIKNNLKDKEVIYLSANLVPRDRKEVIKKIEEALESGRKPIVVSTQVIEAGVDIDFDCVIRDIAPIDSIIQCAGRCNRHNQKSQGKVLVVNIKDDSGRSFAKRVYGNTAIEISNMLLLQHPEVEEKDYGMLIDNYFRMVKENKSFKKSEEFLRSIRLLKFDSILEKEELTISRFSLIQQRGGYVSVVIRSNEEIEDAYQSYINSFSIKDYYKRREIYLELKNILFEHTISVPSKYVQILAEEKGILSLPPTSCERYYNPETGFVYDPNDNVIFA
>NC_015949.1|WP_014043368.1|2557199_2557697_-|CRISPR-associated-protein-Cas4
MDVYMTGVYIWYYNICKRQVWLMAHGVLPDENDDNIVLGRFLHEYYYKKDQKEIKFGNAVFDILYQDKDEIVIGETKKSSRFKEASRYQLLFYIKLLKEAGISAKGVLFYPEERKKEEVELTVEDEEKLQKMIAEIETIIEKDSPPPAAYCRYCPKCAYREYCFA
>NC_015949.1|WP_014043367.1|2556165_2557158_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKDLYVFNSGFLRRKDNTIMFETDEGKKYFPVEEIESVFIFGEVDINKRFLEFMTEKNICVHFFNRYEYYVGTYYPREHYNSGIVILKQVEFYNDYNKRMTIARSIVEGAVLNMLVVLRYYNSRGNILKDEIETIERMRHNINSCDDVNTLMALEGNIREIYYRCFNKILDDENFTFVRRSKNPPLDRINALISFGNSLLYATTLGEIYQTQLDPRIGYLHSTNQRKFSLNLDISEIFKPIIVDRVIFSLVNKKVLSEKHFERELNGIILNDQGKKLFVSEYNQKLYSTITHPKLNCQVSYKRLIRMEAYKLQKLFLENIEYKPFVARW
>NC_015949.1|WP_014043378.1|2575184_2575841_+|MFS-transporter
MVLLTIAISLPHSVLTVLLLAKGITLSQIMIIQAGYSFAVLISEYPSGLIADMYSKKMVFICSKLFLLLMFCLVISMNNFWMLLIAWFMYGISSALDTGTIEAEIINQLKLSGMQIDKFISNSNRLNFIALLIGSSIGSFIYYAIGIKLYWISIILTIVSTICVGIFYKGETSEKTKISLFEIFKRMLVQSKDGIKEMRKKESLKLMIALELALCYVC
>NC_015949.1|WP_014043379.1|2575946_2576273_+|hypothetical-protein
MKLAEEQKSEYDGIAKRVKQEGVEAMGEFISNVARLLDEAKTKYFLAGKLEGKLEGKIEGKLEGKLEATIEFAKRLIKKGFSDEEVAELTELQIEKVKELKKVHGKLT
>NC_015949.1|WP_014043380.1|2576298_2578095_-|ATP-binding-protein
MFNTEIVGRMMKYDSDIYSRYRAEIWFDYTKKAMNEIKEGALLAVQNFSSTSDKIRYCILEITSVIPLHYGLDNDLSGYPGFLTEAAENIYRDWEEQEEEPLDDATKIRCLAIPTNFEIIIDKDQKVSIGIESNLPMVGAEAFLLDEELTNRILNYDIDKSGDVIEIGHLIRDENVKILLKVEELLRVHFGVFGFTGAGKSNLLSTLVRKILTESNLPVKIVIFDLMGEYSTLLVDLLVKLNNSMIVGIGEKTFVGSLISLMKADRSLPEYKDLLKKATIDVVNSSLYPKGLVSHKDLFKKAFFRILQSRKVKIWQSGDIAVADFAKMYERTLLKGNLGKSEALIKKLYEQLLRKTNPLNATVCLALIQYIENKYLSDEKLGSIARSNLELFVNELKKKYEELKEFGFSNENVIDQKKLIEILNSPDDKALVIFQSHDPDELRNLAYQIGMAIFEDRRRSGKIDPVVSFIFDEADEFIPQDAKDSYERSSEVVMHLARRGRKFGLGIGIATQRITYLNTNIMAQPHTYFVSKLPRKSDQERITDAFGISEDMFKQTFKFKKGCWLLVSYDAIGLEAVPLPIYVQNANDAVLEFLKTLQ
>NC_015949.1|WP_014043381.1|2578100_2579951_-|hypothetical-protein
MSKLSQIYGYWKNSIKASMKRYDENMERSLKHLQNFYNMVLKDYIIDWSRYFESQPFRHSLRQKIENFFGKNEINFVAIDGTCVKDEGSDFITFFAGAYGARGKIIIKHEGEKIKYERWDFARDVTMVAQIPVFPYEIEFVASSPELSQMQFYSDKDIQEILNLHTSLMKLAEIYLAYHVVSSSTVDIPQIILLDLAPSTLLRVPYVNYKSTNYLGYKYLNDTIKLSDVIVALSHPYNSLLGVPSRKKYRRYALLLSKLDEVCSQNHKNYFTYKELTEICHLSIEDIKEIVRFLDATGVVEDDEAAGIKLFVNLSQRWSYLVSFFDYICNQIFIRKNPTALEFSNFSEESNIKKLISHDDINFLISIGIRALIEKCWEKNVFLIGIVKDSKSRYFCRNFLNVLSSQNMLGDGKENVDIKNFQIAMSDRLVFENCAALSTELCAPWSSVEFDSAFATLFVDRNNSVTGVKGHIVADDRIFAKSIAQFYLQRSKKQCKMGHAIFVERLLHPSLDRQFLDLVLLENSKLGRLSPFIHLDKKVINWGQAMNIYFLDVLTRNHFPEVIGYPEPLHKADRGAKTLLRFAKGVIHSSQQLYRKDPLNMTFRKFRDKLEFEDEE
>NC_015949.1|WP_014043382.1|2580256_2580394_-|hypothetical-protein
MSLSALLGASIMMHGLVQGLKVFAVVVVLGFVIKGLWQGFKKELA
>NC_015949.1|WP_014043383.1|2580520_2581144_-|hypothetical-protein
MMGCDEKVAKYFTFHFWAREDGVFLPSSYYSKVYEVLKSLLATEQFTISPIKTKNKKEVEDGVWVFEDFRIYLATPFLELFTQNILKIYETLNGLFEGIYLKKISCRSQQPKASGILLSGVFAQKDGVCLEYDRQPEIFSDGLRRQLLNIYYQRFGAYPEDQRFFFVIKDGLKKQHLIRSRIEYFGRYEIFASSELLDMFCQMFCVK
>NC_015949.1|WP_014043384.1|2581140_2582325_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MAHEPFESRTYEIEVLTPTIIGGQDKIQSFEFVKDGDYLYFINFDRLLEENLFKESFIDELSRGLSTGDRDFNIKDVLARYNIDFKNSSKYRLKLEGVKRISKEVVPFVKSAGRFYIPGSSLKGAIRSFVTKALNRNFIQLYENDLSSAYQKTLNSADRRNSVDPKYVCKDAEEKIFATPYESPFKHLKISDSDFVSSENAGVYEIKVMNICGGQVKWFAGRSNEDVPDRAVSIIAEGIKPGAKLIGSIKVEKDFVEGNQVVRGIKEKIGVNASATSPTEFLADVLKVVSKDYIQREINFYTRYKQAQIVSEYQKLLNVLNSLDKNQFLIQIGFSTGYLSKTVGIFFNKNHFEKLAKVDRQSKIYPELFPKTRRLVFKNGQVWTVPGWIKVTIK
>NC_015949.1|WP_014043385.1|2582314_2583325_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MSKGKLYRVSMRFSSPLHIGEKEKIYNITQTFAHSDTLMSGIINAYSLLYGNSSTNELLDGFLRKSPPFEVSSTMPYVQGEFFVPKPAGLNLHHYKDEGKIEVENDKELKKIKFIRENDLLYNFPDKYKAAGSFLLPRDMLYKFVESKKHISLGKVKERARVSIDRLSSSSNIYYFSHFEFEESAGLWFYLRINDQSLEEKIKAAIRLLGDEGLGGDRTCGLGSFEANFEESSMPEENDSAKYYMSLSLVNPQSEDEIKSAISYEILTRSGYIYSKAGLGIKRKALRVFSEGTVFSGKVCGRVVDVTPQKFSQHRVYCFALAFLLPLPEGVMMIGS
>NC_015949.1|WP_014043386.1|2583352_2584180_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MDVILKGKYIIKCKIEAVTGLHIGEGNNSIEIGGIDNSVVKDAEGKPYIPGSSLKGKMRALMEFAEGKVKDDLMVVAVKKGDKPEICIHMCEDIDCPVCGLFGRNHGKHVTKEEFIRNPNAEGKDFSDAVIPTRLIVRDAKLIDSSITDEMKENLDLEWTEVKFENNIDRITSKATPRQSERVPAGAQFSAEFVVNRYEVDGSDDGQRYLSKFIKAMKLLEDDYLGGQGSRGNGKVKFVDIEIVYKDSSDYEKDSSDLKPIAKADSLDQLKLSTN
>NC_015949.1|WP_014043387.1|2584207_2584618_-|type-III-A-CRISPR-associated-protein-Csm2
MPAQGGNVALSLKNDILSKIETAIDPEKDKDGKAFSDVSEKTGQLLKESGVTVTQIRKVFTEVKRLSPEDDNYKYKLKLLKAKLAYTAGRFNKMKDFQEIINKALPVAEKSPEALNRFKDFFEAAVAYHKYFGGKE

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Crispr_ID: NC_015949_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_6

2587709-2589338

TypeIII

Consensus_repeat	Method
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	PILER-CR
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CRISPRCasFinder
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CRT

24 spacers

cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6,csx1

The CRISPR arrays of NC_015949_6

>merge|NC_015949|6|2587709-2589338|PILER-CR,CRISPRCasFinder,CRT
GTTTGTAGCCTTCCCTTTGGGGATTGAAACAATTTTGTCATATCCTTCCACTCAGGGAAAGCAGAGGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCTCCTTTACAAAAAGAATCAGGCTCGGAGAGGCGGGTTTGTAGCCTTCCCTTTGGGGATTGAAACCCAACAACGTGCCTAACACCAGCGGTGCTAAATACAAGGTTTGTAGCCTTCCCTTTGGGGATTGAAACATCCACGTCTTCTTGTGTAAAACTTTTAGATTGGGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCAGCTAACTCCCTAACAACGACATCAAGTCGACTAACGGTTTGTAGCCTTCCCTTTGGGGATTGAAACAAGTATTTCGATAATTCATCATCTAAAAAACCATCAGGTTTGTAGCCTTCCCTTTGGGGATTGAAACGTATGAATTAACTAAACTGTCCCATGTAACAACTTCATCGTTTGTAGCCTTCCCTTTGGGGATTGAAACTTATCAAACATGGTGCGTCAACTATGAGTAACAATGTTTGTAGCCTTCCCTTTGGGGATTGAAACACAAACTTGACGCCAAAGAGTTTGCCTATCTCACCGTGTTTGTAGCCTTCCCTTTGGGGATTGAAACTTCACTTTTTCCCAGCATTCGCAACAAACTTGTAAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACTGCACACCATCAGTTGCCGGTGCAACCGACCCCTCAACGTTTGTAGCCTTCCCTTTGGGGATTGAAACAAAACCTAAAGGGGAATTTTTGTTCCTCATTGAAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACCCGTCGTTTTAGTCGTTACAGTTATAGATATAGCTTTTGGTTTGTAGCCTTCCCTTTGGGGATTGAAACCCTTTTAGAGCATAGTACATTTCAGCTACATAATCAGTTTGTAGCCTTCCCTTTGGGGATTGAAACATGCCATCAAAGCCATAACAAAAACAACAGCAATAGGTTTGTAGCCTTCCCTTTGGGGATTGAAACCTTCTAAAACTGTTTTCCTTGCAAAGTCCTTGTCGATAGTTTGTAGCCTTCCCTTTGGGGATTGAAACAATTACCAGCAAACAGGCACTATAATTGGTTGTTGCGTTTGTAGCCTTCCCTTTGGGGATTGAAACCTCTTTTGCTTTCGTACTTTTGCTTTGTCTTCAGTATCGTTTGTAGCCTTCCCTTTGGGGATTGAAACTCCTGTGAGGCAATGCGTTCGTTGTCTTTTTGCTTTGTTTGTAGCCTTCCCTTTGGGGATTGAAACGGTGGAATGATGATATACTCAATTCTAACATCCTCAGTTTGTAGCCTTCCCTTTGGGGATTGAAACGAAAACATCACAAAAGACGGCACACGAGGATTACTAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACGTTAAATCAAAACTCTCAATCTCTGCTATCTTTACGTTTGTAGCCTTCCCTTTGGGGATTGAAACTATTTTTATTTCCACTGGCAAGAGAGGAATGGAATTAGTTTGTAGCCTCCCCTTTGGGGATTGAAACCCAAGAATAAACTCATCAAGGTTAGTAGTGCAGTTGGTTTGTAGCCTTCCCTTTGGGGATTGAGGT

>NC_015949|6|6|2587709-2589272|PILER-CR
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATTTTGTCATATCCTTCCACTCAGGGAAAGCAGAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTCCTTTACAAAAAGAATCAGGCTCGGAGAGGCGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCAACAACGTGCCTAACACCAGCGGTGCTAAATACAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATCCACGTCTTCTTGTGTAAAACTTTTAGATTGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCAGCTAACTCCCTAACAACGACATCAAGTCGACTAACG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAGTATTTCGATAATTCATCATCTAAAAAACCATCAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GTATGAATTAACTAAACTGTCCCATGTAACAACTTCATC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTATCAAACATGGTGCGTCAACTATGAGTAACAAT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACAAACTTGACGCCAAAGAGTTTGCCTATCTCACCGT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTCACTTTTTCCCAGCATTCGCAACAAACTTGTAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGCACACCATCAGTTGCCGGTGCAACCGACCCCTCAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAAACCTAAAGGGGAATTTTTGTTCCTCATTGAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCGTCGTTTTAGTCGTTACAGTTATAGATATAGCTTTTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCTTTTAGAGCATAGTACATTTCAGCTACATAATCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATGCCATCAAAGCCATAACAAAAACAACAGCAATAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTTCTAAAACTGTTTTCCTTGCAAAGTCCTTGTCGATA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATTACCAGCAAACAGGCACTATAATTGGTTGTTGC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTCTTTTGCTTTCGTACTTTTGCTTTGTCTTCAGTATC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCCTGTGAGGCAATGCGTTCGTTGTCTTTTTGCTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GGTGGAATGATGATATACTCAATTCTAACATCCTCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GAAAACATCACAAAAGACGGCACACGAGGATTACTAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GTTAAATCAAAACTCTCAATCTCTGCTATCTTTAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TATTTTTATTTCCACTGGCAAGAGAGGAATGGAATTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC

>NC_015949|6|6|2587709-2589338|CRISPRCasFinder
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATTTTGTCATATCCTTCCACTCAGGGAAAGCAGAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTCCTTTACAAAAAGAATCAGGCTCGGAGAGGCGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCAACAACGTGCCTAACACCAGCGGTGCTAAATACAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATCCACGTCTTCTTGTGTAAAACTTTTAGATTGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCAGCTAACTCCCTAACAACGACATCAAGTCGACTAACG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAGTATTTCGATAATTCATCATCTAAAAAACCATCAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GTATGAATTAACTAAACTGTCCCATGTAACAACTTCATC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTATCAAACATGGTGCGTCAACTATGAGTAACAAT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACAAACTTGACGCCAAAGAGTTTGCCTATCTCACCGT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTCACTTTTTCCCAGCATTCGCAACAAACTTGTAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGCACACCATCAGTTGCCGGTGCAACCGACCCCTCAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAAACCTAAAGGGGAATTTTTGTTCCTCATTGAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCGTCGTTTTAGTCGTTACAGTTATAGATATAGCTTTTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCTTTTAGAGCATAGTACATTTCAGCTACATAATCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATGCCATCAAAGCCATAACAAAAACAACAGCAATAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTTCTAAAACTGTTTTCCTTGCAAAGTCCTTGTCGATA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATTACCAGCAAACAGGCACTATAATTGGTTGTTGC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTCTTTTGCTTTCGTACTTTTGCTTTGTCTTCAGTATC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCCTGTGAGGCAATGCGTTCGTTGTCTTTTTGCTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GGTGGAATGATGATATACTCAATTCTAACATCCTCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GAAAACATCACAAAAGACGGCACACGAGGATTACTAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GTTAAATCAAAACTCTCAATCTCTGCTATCTTTAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TATTTTTATTTCCACTGGCAAGAGAGGAATGGAATTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CCAAGAATAAACTCATCAAGGTTAGTAGTGCAGTTG
GTTTGTAGCCTTCCCTTTGGGGATTGAGGT

>NC_015949|6|6|2587709-2589338|CRT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATTTTGTCATATCCTTCCACTCAGGGAAAGCAGAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCTCCTTTACAAAAAGAATCAGGCTCGGAGAGGCGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCAACAACGTGCCTAACACCAGCGGTGCTAAATACAAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATCCACGTCTTCTTGTGTAAAACTTTTAGATTGG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCAGCTAACTCCCTAACAACGACATCAAGTCGACTAACG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAGTATTTCGATAATTCATCATCTAAAAAACCATCAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GTATGAATTAACTAAACTGTCCCATGTAACAACTTCATC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTATCAAACATGGTGCGTCAACTATGAGTAACAAT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACAAACTTGACGCCAAAGAGTTTGCCTATCTCACCGT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TTCACTTTTTCCCAGCATTCGCAACAAACTTGTAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TGCACACCATCAGTTGCCGGTGCAACCGACCCCTCAAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AAAACCTAAAGGGGAATTTTTGTTCCTCATTGAAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCGTCGTTTTAGTCGTTACAGTTATAGATATAGCTTTTG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CCTTTTAGAGCATAGTACATTTCAGCTACATAATCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ATGCCATCAAAGCCATAACAAAAACAACAGCAATAG
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTTCTAAAACTGTTTTCCTTGCAAAGTCCTTGTCGATA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AATTACCAGCAAACAGGCACTATAATTGGTTGTTGC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CTCTTTTGCTTTCGTACTTTTGCTTTGTCTTCAGTATC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TCCTGTGAGGCAATGCGTTCGTTGTCTTTTTGCTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GGTGGAATGATGATATACTCAATTCTAACATCCTCA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GAAAACATCACAAAAGACGGCACACGAGGATTACTAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GTTAAATCAAAACTCTCAATCTCTGCTATCTTTAC
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	TATTTTTATTTCCACTGGCAAGAGAGGAATGGAATTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CCAAGAATAAACTCATCAAGGTTAGTAGTGCAGTTG
GTTTGTAGCCTTCCCTTTGGGGATTGAGGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_014043387.1\|2584207_2584618_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NC_015949.1\|WP_014043385.1\|2582314_2583325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|273866
NC_015949.1\|WP_014043398.1\|2602084_2602594_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366961
NC_015949.1\|WP_014043382.1\|2580256_2580394_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043394.1\|2597253_2597460_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043386.1\|2583352_2584180_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_015949.1\|WP_014043391.1\|2593065_2594484_-\|TIGR01897-family-CRISPR-associated-protein	csx1	cd09728_csx1_CAS-III	gnl\|CDD\|187859
NC_015949.1\|WP_014043383.1\|2580520_2581144_-\|hypothetical-protein	cas6	mkCas0062_cas6_CAS-I:CAS-III	unknown
NC_015949.1\|WP_014043393.1\|2595729_2596668_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381149
NC_015949.1\|WP_014043396.1\|2600174_2600984_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|110924
NC_015949.1\|WP_014043388.1\|2584650_2587134_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NC_015949.1\|WP_014043381.1\|2578100_2579951_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NC_015949.1\|WP_014043389.1\|2590956_2591253_+\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_041725700.1\|2599511_2599886_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043379.1\|2575946_2576273_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273806
NC_015949.1\|WP_014043392.1\|2594617_2595712_-\|DUF1848-domain-containing-protein	unknown	unknown	gnl\|CDD\|378091
NC_015949.1\|WP_014043380.1\|2576298_2578095_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|223510
NC_015949.1\|WP_167317459.1\|2599992_2600193_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043397.1\|2601013_2601742_-\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|223777

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_014043387.1\|2584207_2584618_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	1.09819e-32
NC_015949.1\|WP_014043385.1\|2582314_2583325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	1.20453e-51
NC_015949.1\|WP_014043398.1\|2602084_2602594_+\|hypothetical-protein	gnl\|CDD\|366961	pfam02183, HALZ, Homeobox associated leucine zipper.	7.6091e-05
NC_015949.1\|WP_014043386.1\|2583352_2584180_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	6.51835e-76
NC_015949.1\|WP_014043391.1\|2593065_2594484_-\|TIGR01897-family-CRISPR-associated-protein	gnl\|CDD\|187859	cd09728, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as DxTHG family.	2.6701e-42
NC_015949.1\|WP_014043393.1\|2595729_2596668_-\|hypothetical-protein	gnl\|CDD\|381149	cd19922, REC_RitR-like, receiver (REC) domain of orphan response regulator RitR and similar domains. Streptococcus pneumoniae RitR (Repressor of iron transport Regulator, formerly RR489) is an orphan two-component signal transduction response regulator that is required for lung pathogenicity. It acts to repress iron uptake via binding the pneumococcal iron uptake (Piu) transporter promoter. Members of this subfamily contain REC and DNA-binding output domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. However, members of this family do not contain the phosphorylatable aspartic acid residue and are phosphorylation-independent.	0.00574532
NC_015949.1\|WP_014043396.1\|2600174_2600984_-\|hypothetical-protein	gnl\|CDD\|110924	pfam01972, SDH_sah, Serine dehydrogenase proteinase. This family of archaebacterial proteins, formerly known as DUF114, has been found to be a serine dehydrogenase proteinase distantly related to ClpP proteinases that belong to the serine proteinase superfamily. The family has a catalytic triad of Ser, Asp, His residues, which shows an altered residue ordering compared with the ClpP proteinases but similar to that of the carboxypeptidase clan.	8.36863e-114
NC_015949.1\|WP_014043388.1\|2584650_2587134_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	6.95588e-105
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	4.63196e-24
NC_015949.1\|WP_014043397.1\|2601013_2601742_-\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	1.41364e-35
NC_015949.1\|WP_014043379.1\|2575946_2576273_+\|hypothetical-protein	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.4693e-08
NC_015949.1\|WP_014043392.1\|2594617_2595712_-\|DUF1848-domain-containing-protein	gnl\|CDD\|378091	pfam08902, DUF1848, Domain of unknown function (DUF1848). This family of proteins are functionally uncharacterized. The C-terminus contains a cluster of cysteines that are similar to the iron-sulfur cluster found at the N-terminus of pfam04055.	1.28051e-142
NC_015949.1\|WP_014043380.1\|2576298_2578095_-\|ATP-binding-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	2.70685e-17

>NC_015949.1|WP_014043388.1|2584650_2587134_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MIFYSAHQREEDRNFDYTLFLGAILHDIGKFYMRTENPDAKKNISKEYEAFYQAEGKYAPRHQEWGAFFVEHFLPESLKGVTSLVLYHHRPSSYDQLLISVADKISAKVDRKDISEEEAAGDKSKYLISVLSQISLDRDKKEPKKPFYKLLKKRYDVENPTEGFSSNAKEDYQNLWAEFSRKISILRDGFESSFDLEDFATAVYNLLRLYTYNVPSAFYHSQPDISLWAHSKSTAAIAFCLDRQLKKEFSQENERIRDLEAINTKLLPGNESAIKKGDYPYFCLVKGDVSGIQDFVFDTSMDGALKALKGKSFYISFLLDTIARYILKEENMPVCNLMYNGGGHFYLLMPRYFMEKLSHYQQKIDKILFSAHRGALSVLLEAAEVDLYDFARNFGDCFDRVSRNIQKKKACKLKNVLEETKMKFFEPWEDHDLKCPHCGRKIEPKEDNPDYCRFCDSFVKLGDELMKSLFIVDSWGEEKEFSEFFNIHNVLKAFGRTIEFSNHYESVANTLILDRSRIEDLQIKKKEIERGQKGSKQGFESEFYEDLDISTHVPFKDVNEEVLMLIDDIAESAKGIKTWGIVRGDVDNLGSIFKDGLGKDNSISRVMTLSEEFSLFFGYYFNKLVKKQDGNILVIYAGGDDFCILGQWDVLPQIAHKIYTEFRNFSCHNPDVTLSMGFEIAPDKKYPIYRVAMVCGDHLDQAKEYEREDGKKKDCFAFGANFVGWEEFEDLKKLKEAIADLVGNKNVSKALINGIYAVCNLKKVAQAQKELFKAWRFVYFMARLKERHSKFSAELEDVLDKIIDKKTNALYKHSYLAARWAELELRR
>NC_015949.1|WP_014043387.1|2584207_2584618_-|type-III-A-CRISPR-associated-protein-Csm2
MPAQGGNVALSLKNDILSKIETAIDPEKDKDGKAFSDVSEKTGQLLKESGVTVTQIRKVFTEVKRLSPEDDNYKYKLKLLKAKLAYTAGRFNKMKDFQEIINKALPVAEKSPEALNRFKDFFEAAVAYHKYFGGKE
>NC_015949.1|WP_014043386.1|2583352_2584180_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MDVILKGKYIIKCKIEAVTGLHIGEGNNSIEIGGIDNSVVKDAEGKPYIPGSSLKGKMRALMEFAEGKVKDDLMVVAVKKGDKPEICIHMCEDIDCPVCGLFGRNHGKHVTKEEFIRNPNAEGKDFSDAVIPTRLIVRDAKLIDSSITDEMKENLDLEWTEVKFENNIDRITSKATPRQSERVPAGAQFSAEFVVNRYEVDGSDDGQRYLSKFIKAMKLLEDDYLGGQGSRGNGKVKFVDIEIVYKDSSDYEKDSSDLKPIAKADSLDQLKLSTN
>NC_015949.1|WP_014043385.1|2582314_2583325_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MSKGKLYRVSMRFSSPLHIGEKEKIYNITQTFAHSDTLMSGIINAYSLLYGNSSTNELLDGFLRKSPPFEVSSTMPYVQGEFFVPKPAGLNLHHYKDEGKIEVENDKELKKIKFIRENDLLYNFPDKYKAAGSFLLPRDMLYKFVESKKHISLGKVKERARVSIDRLSSSSNIYYFSHFEFEESAGLWFYLRINDQSLEEKIKAAIRLLGDEGLGGDRTCGLGSFEANFEESSMPEENDSAKYYMSLSLVNPQSEDEIKSAISYEILTRSGYIYSKAGLGIKRKALRVFSEGTVFSGKVCGRVVDVTPQKFSQHRVYCFALAFLLPLPEGVMMIGS
>NC_015949.1|WP_014043384.1|2581140_2582325_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MAHEPFESRTYEIEVLTPTIIGGQDKIQSFEFVKDGDYLYFINFDRLLEENLFKESFIDELSRGLSTGDRDFNIKDVLARYNIDFKNSSKYRLKLEGVKRISKEVVPFVKSAGRFYIPGSSLKGAIRSFVTKALNRNFIQLYENDLSSAYQKTLNSADRRNSVDPKYVCKDAEEKIFATPYESPFKHLKISDSDFVSSENAGVYEIKVMNICGGQVKWFAGRSNEDVPDRAVSIIAEGIKPGAKLIGSIKVEKDFVEGNQVVRGIKEKIGVNASATSPTEFLADVLKVVSKDYIQREINFYTRYKQAQIVSEYQKLLNVLNSLDKNQFLIQIGFSTGYLSKTVGIFFNKNHFEKLAKVDRQSKIYPELFPKTRRLVFKNGQVWTVPGWIKVTIK
>NC_015949.1|WP_014043383.1|2580520_2581144_-|hypothetical-protein
MMGCDEKVAKYFTFHFWAREDGVFLPSSYYSKVYEVLKSLLATEQFTISPIKTKNKKEVEDGVWVFEDFRIYLATPFLELFTQNILKIYETLNGLFEGIYLKKISCRSQQPKASGILLSGVFAQKDGVCLEYDRQPEIFSDGLRRQLLNIYYQRFGAYPEDQRFFFVIKDGLKKQHLIRSRIEYFGRYEIFASSELLDMFCQMFCVK
>NC_015949.1|WP_014043382.1|2580256_2580394_-|hypothetical-protein
MSLSALLGASIMMHGLVQGLKVFAVVVVLGFVIKGLWQGFKKELA
>NC_015949.1|WP_014043381.1|2578100_2579951_-|hypothetical-protein
MSKLSQIYGYWKNSIKASMKRYDENMERSLKHLQNFYNMVLKDYIIDWSRYFESQPFRHSLRQKIENFFGKNEINFVAIDGTCVKDEGSDFITFFAGAYGARGKIIIKHEGEKIKYERWDFARDVTMVAQIPVFPYEIEFVASSPELSQMQFYSDKDIQEILNLHTSLMKLAEIYLAYHVVSSSTVDIPQIILLDLAPSTLLRVPYVNYKSTNYLGYKYLNDTIKLSDVIVALSHPYNSLLGVPSRKKYRRYALLLSKLDEVCSQNHKNYFTYKELTEICHLSIEDIKEIVRFLDATGVVEDDEAAGIKLFVNLSQRWSYLVSFFDYICNQIFIRKNPTALEFSNFSEESNIKKLISHDDINFLISIGIRALIEKCWEKNVFLIGIVKDSKSRYFCRNFLNVLSSQNMLGDGKENVDIKNFQIAMSDRLVFENCAALSTELCAPWSSVEFDSAFATLFVDRNNSVTGVKGHIVADDRIFAKSIAQFYLQRSKKQCKMGHAIFVERLLHPSLDRQFLDLVLLENSKLGRLSPFIHLDKKVINWGQAMNIYFLDVLTRNHFPEVIGYPEPLHKADRGAKTLLRFAKGVIHSSQQLYRKDPLNMTFRKFRDKLEFEDEE
>NC_015949.1|WP_014043380.1|2576298_2578095_-|ATP-binding-protein
MFNTEIVGRMMKYDSDIYSRYRAEIWFDYTKKAMNEIKEGALLAVQNFSSTSDKIRYCILEITSVIPLHYGLDNDLSGYPGFLTEAAENIYRDWEEQEEEPLDDATKIRCLAIPTNFEIIIDKDQKVSIGIESNLPMVGAEAFLLDEELTNRILNYDIDKSGDVIEIGHLIRDENVKILLKVEELLRVHFGVFGFTGAGKSNLLSTLVRKILTESNLPVKIVIFDLMGEYSTLLVDLLVKLNNSMIVGIGEKTFVGSLISLMKADRSLPEYKDLLKKATIDVVNSSLYPKGLVSHKDLFKKAFFRILQSRKVKIWQSGDIAVADFAKMYERTLLKGNLGKSEALIKKLYEQLLRKTNPLNATVCLALIQYIENKYLSDEKLGSIARSNLELFVNELKKKYEELKEFGFSNENVIDQKKLIEILNSPDDKALVIFQSHDPDELRNLAYQIGMAIFEDRRRSGKIDPVVSFIFDEADEFIPQDAKDSYERSSEVVMHLARRGRKFGLGIGIATQRITYLNTNIMAQPHTYFVSKLPRKSDQERITDAFGISEDMFKQTFKFKKGCWLLVSYDAIGLEAVPLPIYVQNANDAVLEFLKTLQ
>NC_015949.1|WP_014043379.1|2575946_2576273_+|hypothetical-protein
MKLAEEQKSEYDGIAKRVKQEGVEAMGEFISNVARLLDEAKTKYFLAGKLEGKLEGKIEGKLEGKLEATIEFAKRLIKKGFSDEEVAELTELQIEKVKELKKVHGKLT
>NC_015949.1|WP_014043389.1|2590956_2591253_+|hypothetical-protein
MSDIKIIQEDIKHEVAIDIIAGLLGSLTNIKLKTVHSDLDKEIKEQKLQKIEKIRETLCKERDHVYRGDKDAIERALTTYALLYRLIDEEEVINAEVF
>NC_015949.1|WP_014043391.1|2593065_2594484_-|TIGR01897-family-CRISPR-associated-protein
MKVIYQVGRLDNPAQATKEFYIKNFHGEKVDESGKAELSSIVLRDFLRKRNYEAKTVIVYPVSIVFNSKLPEYIQPEELKNELVDIFKDPSNYLKNPHEFIERIELERNRDEKLIVHSLGEYLGISLDASYDDIVLEILFDMIERYLKGELEELYLDISSGHNIYISAILEAARHFAVFSHLVNWIDDTKSPKIYITFSDPIIGSSAKSFEIHIQQQRFTAFFSSPIKSKEAADYNFSFLREIYPDPNNNSKGSEAVKLKQQAREKRKKLKEKIEMFCLLFSAIKNNVPLYLYSQHYHSADEIKEEIFKLIDHAKARLCSDYQKSPNLNKRAYIDAVLSLGFYIGIVNVLEKYNVTMFCHDTGIDIETVKNSFSEIYLIFRLHTNIVMLGNEVSNTQEKLKQIGDISTWTGLYRIIDPDKSAGEIDPRNFFAHSGFERNATEVRTDDDRVLVRYSLNVNFNDINCWLKRRLE
>NC_015949.1|WP_014043392.1|2594617_2595712_-|DUF1848-domain-containing-protein
MIISASRRTDIPAFFGDWFINRIKEGFAMYRNPMRPTQVFAVSLHPKDVDAIVFWTKNPKNFLDKLKYLDEYIYYFQFTLTPYAQDLEPGIPNKDEVIETFIKLSDMIGKKRVIWRYDPIIITDKMPLDYHKEKFEELCEKLSPYTQKCIISYVDFYSKAEDELNKINAKRLEQDDLYNLFSAVGSIGKKYNLSVETCAEDVPVEYLGLKKAHCVDGDLINELRKEKGFQDKEYRKDNNQRKACGCVQSIDLGIFNTCKHFCVYCYANFSRNSIIKNAQKYDVNSPLLCSALDLEKDEIRIREKDGSKKLEISHILEQDKNQERKISQLDFCVQQINSVEKNTNSSLEKKVLDHIKRIKQRTLL
>NC_015949.1|WP_014043393.1|2595729_2596668_-|hypothetical-protein
MCLLVYDVMRMAKERHSSVCLSSLNSLFQRESNCERCLPNVHFKRKNNGNVRDYDCKNMIYYYCGRYSLKHAGELFTLLQQISHRLPDNPRILSIGCGPCTDLFAFEAYFKTYKPYKKIEYHGLEKNMLWKDIHDFITKHGKKHNLSRFRITYIDVMSEVQKVEEIIKNEKPNIISFQYVLSDMAKYHPVSSVKRFAEEFVQKAFEILPKSTMIVFNDTNVLQRYAERNPDEVKGRDILEPLADKFWHSRNISVFKYYFPYRNDPSLQFGGAHSKCEVDMGNVPADLKNYFEIWYEYRSAQLVLIKNEDILI
>NC_015949.1|WP_014043394.1|2597253_2597460_-|hypothetical-protein
MDIIDENNVDLFQSPKGRLQTIIHTLGLESVSEVSIPNGKATNLPIDDWMIIVEACFNPQREGYKPRR
>NC_015949.1|WP_041725700.1|2599511_2599886_-|hypothetical-protein
MIFEGSAYSGTKQIANIVSKDYSDYQKILWVVSHGYMSLISGNFMPESYVKRRHFAKVLIKLSGDIANLANPEKSTFVDVLKTDFRNYETGNTASSRILCGLIYVLSLRIFIPSILHNYKIFII
>NC_015949.1|WP_167317459.1|2599992_2600193_-|hypothetical-protein
MAAKEIVKNFTHETQSSSEGDYTTFYEEGLAYMYSELEKVKIYYTSAGYTNVTFAVHHLASLMSMK
>NC_015949.1|WP_014043396.1|2600174_2600984_-|hypothetical-protein
MSFWDLLILYVIATSLQPIMKQRMIESARQKLIARIEKKRGSRVILLVHRQETMSFLGFPIYKYIDINDSEEVIRAISMTDPSVPLDIILHTPGGLVLASLQIARAIKRHKGKVTVHVPHHAMSGGTLIALAADEIVMAPDAVLGPVDPQIGEFPAVSILEVVKQKPIADIDDKTLILADVAKKALRQTKDAVLELLSGNYPDDVAENIATQLVEGRWTHDYPITYEKAKELGLKVRCDIDKEIQQLMSLYPQPVVKKSSVEYLWQPRK
>NC_015949.1|WP_014043397.1|2601013_2601742_-|rhomboid-family-intramembrane-serine-protease
MIPLKDTIPSREKPFMTWTLILINVFVFLYQVSMPQEAAQEFVFRYGFVPERFTQLLSHGFVVAASVSIWSIITSMFLHGSWMHLISNMWSLWLFGDNVEDRVGHFRFLIFYILSGFAAALTHWFFNANSPIPTVGASGAISGVMGAYFLMFPLSRIVTLIPLGFIPLFIEIPAIFFLGIWFLSQVSSGILELFGPVFGSGIAWWAHIGGFVFGVLTINMFKKKYRRYRNFFDDEIFYYRYF
>NC_015949.1|WP_014043398.1|2602084_2602594_+|hypothetical-protein
MKKRLLAFLSFVILISFALGVVASSPTNYKALYEKLLKDYNVLKSENQKLKNEVTTLKKKTDDLQKKVTSLPQLSYYDIVVNGVSTAQKVPFISYGGRRYVHFDSMLKTFLNVGDTGYIFNDQTKRVEIGAFVKNKSGIWLSDLQYFDRKGDWSDFGFNATDIMQLILL

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Crispr_ID: NC_015949_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_7

2592728-2592897

TypeIII

Consensus_repeat	Method
GTTTGTAGCCTTCCCTTTGGGGATTGA	CRISPRCasFinder

2 spacers

cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6,csx1

The CRISPR arrays of NC_015949_7

>merge|NC_015949|7|2592728-2592897|CRISPRCasFinder
GTTTGTAGCCTTCCCTTTGGGGATTGAAACGTTAAATCAAAACTCTCAATCTCTGCTATCTTTACGTTTGTAGCCTTCCCTTTGGGGATTGAGGTGGTGGAGGGGTTTGTAGCCTTCCCTTTGGGGATTGAGGTGGTGGAGGGGTTTGTAGCCTCTCAGCTGGGGATTGA

>NC_015949|7|7|2592728-2592897|CRISPRCasFinder
GTTTGTAGCCTTCCCTTTGGGGATTGA	AACGTTAAATCAAAACTCTCAATCTCTGCTATCTTTAC
GTTTGTAGCCTTCCCTTTGGGGATTGA	GGTGGTGGAGGGGTTTGTAGCCTTCCCTTTGGGGATTGAGGTGGTGGAGGG
GTTTGTAGCCTCTCAGCTGGGGATTGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_014043387.1\|2584207_2584618_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NC_015949.1\|WP_014043385.1\|2582314_2583325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|273866
NC_015949.1\|WP_014043398.1\|2602084_2602594_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366961
NC_015949.1\|WP_014043382.1\|2580256_2580394_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043394.1\|2597253_2597460_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043386.1\|2583352_2584180_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_015949.1\|WP_014043391.1\|2593065_2594484_-\|TIGR01897-family-CRISPR-associated-protein	csx1	cd09728_csx1_CAS-III	gnl\|CDD\|187859
NC_015949.1\|WP_014043383.1\|2580520_2581144_-\|hypothetical-protein	cas6	mkCas0062_cas6_CAS-I:CAS-III	unknown
NC_015949.1\|WP_014043393.1\|2595729_2596668_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381149
NC_015949.1\|WP_083825670.1\|2602584_2602935_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377970
NC_015949.1\|WP_014043396.1\|2600174_2600984_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|110924
NC_015949.1\|WP_014043388.1\|2584650_2587134_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NC_015949.1\|WP_014043381.1\|2578100_2579951_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NC_015949.1\|WP_014043389.1\|2590956_2591253_+\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_041725700.1\|2599511_2599886_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043392.1\|2594617_2595712_-\|DUF1848-domain-containing-protein	unknown	unknown	gnl\|CDD\|378091
NC_015949.1\|WP_014043380.1\|2576298_2578095_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|223510
NC_015949.1\|WP_167317459.1\|2599992_2600193_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043397.1\|2601013_2601742_-\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|223777

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_014043387.1\|2584207_2584618_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	1.09819e-32
NC_015949.1\|WP_014043385.1\|2582314_2583325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	1.20453e-51
NC_015949.1\|WP_014043398.1\|2602084_2602594_+\|hypothetical-protein	gnl\|CDD\|366961	pfam02183, HALZ, Homeobox associated leucine zipper.	7.6091e-05
NC_015949.1\|WP_014043386.1\|2583352_2584180_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	6.51835e-76
NC_015949.1\|WP_014043391.1\|2593065_2594484_-\|TIGR01897-family-CRISPR-associated-protein	gnl\|CDD\|187859	cd09728, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as DxTHG family.	2.6701e-42
NC_015949.1\|WP_014043393.1\|2595729_2596668_-\|hypothetical-protein	gnl\|CDD\|381149	cd19922, REC_RitR-like, receiver (REC) domain of orphan response regulator RitR and similar domains. Streptococcus pneumoniae RitR (Repressor of iron transport Regulator, formerly RR489) is an orphan two-component signal transduction response regulator that is required for lung pathogenicity. It acts to repress iron uptake via binding the pneumococcal iron uptake (Piu) transporter promoter. Members of this subfamily contain REC and DNA-binding output domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. However, members of this family do not contain the phosphorylatable aspartic acid residue and are phosphorylation-independent.	0.00574532
NC_015949.1\|WP_083825670.1\|2602584_2602935_+\|hypothetical-protein	gnl\|CDD\|377970	pfam08305, NPCBM, NPCBM/NEW2 domain. This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins. This domain has also been called the NEW2 domain (Naumoff DG. Phylogenetic analysis of alpha-galactosidases of the GH27 family. Molecular Biology (Engl Transl). (2004)38:388-399.).	8.2555e-08
NC_015949.1\|WP_014043396.1\|2600174_2600984_-\|hypothetical-protein	gnl\|CDD\|110924	pfam01972, SDH_sah, Serine dehydrogenase proteinase. This family of archaebacterial proteins, formerly known as DUF114, has been found to be a serine dehydrogenase proteinase distantly related to ClpP proteinases that belong to the serine proteinase superfamily. The family has a catalytic triad of Ser, Asp, His residues, which shows an altered residue ordering compared with the ClpP proteinases but similar to that of the carboxypeptidase clan.	8.36863e-114
NC_015949.1\|WP_014043388.1\|2584650_2587134_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	6.95588e-105
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	4.63196e-24
NC_015949.1\|WP_014043397.1\|2601013_2601742_-\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	1.41364e-35
NC_015949.1\|WP_014043392.1\|2594617_2595712_-\|DUF1848-domain-containing-protein	gnl\|CDD\|378091	pfam08902, DUF1848, Domain of unknown function (DUF1848). This family of proteins are functionally uncharacterized. The C-terminus contains a cluster of cysteines that are similar to the iron-sulfur cluster found at the N-terminus of pfam04055.	1.28051e-142
NC_015949.1\|WP_014043380.1\|2576298_2578095_-\|ATP-binding-protein	gnl\|CDD\|223510	COG0433, COG0433, HerA helicase [Replication, recombination, and repair].	2.70685e-17

>NC_015949.1|WP_014043389.1|2590956_2591253_+|hypothetical-protein
MSDIKIIQEDIKHEVAIDIIAGLLGSLTNIKLKTVHSDLDKEIKEQKLQKIEKIRETLCKERDHVYRGDKDAIERALTTYALLYRLIDEEEVINAEVF
>NC_015949.1|WP_014043388.1|2584650_2587134_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MIFYSAHQREEDRNFDYTLFLGAILHDIGKFYMRTENPDAKKNISKEYEAFYQAEGKYAPRHQEWGAFFVEHFLPESLKGVTSLVLYHHRPSSYDQLLISVADKISAKVDRKDISEEEAAGDKSKYLISVLSQISLDRDKKEPKKPFYKLLKKRYDVENPTEGFSSNAKEDYQNLWAEFSRKISILRDGFESSFDLEDFATAVYNLLRLYTYNVPSAFYHSQPDISLWAHSKSTAAIAFCLDRQLKKEFSQENERIRDLEAINTKLLPGNESAIKKGDYPYFCLVKGDVSGIQDFVFDTSMDGALKALKGKSFYISFLLDTIARYILKEENMPVCNLMYNGGGHFYLLMPRYFMEKLSHYQQKIDKILFSAHRGALSVLLEAAEVDLYDFARNFGDCFDRVSRNIQKKKACKLKNVLEETKMKFFEPWEDHDLKCPHCGRKIEPKEDNPDYCRFCDSFVKLGDELMKSLFIVDSWGEEKEFSEFFNIHNVLKAFGRTIEFSNHYESVANTLILDRSRIEDLQIKKKEIERGQKGSKQGFESEFYEDLDISTHVPFKDVNEEVLMLIDDIAESAKGIKTWGIVRGDVDNLGSIFKDGLGKDNSISRVMTLSEEFSLFFGYYFNKLVKKQDGNILVIYAGGDDFCILGQWDVLPQIAHKIYTEFRNFSCHNPDVTLSMGFEIAPDKKYPIYRVAMVCGDHLDQAKEYEREDGKKKDCFAFGANFVGWEEFEDLKKLKEAIADLVGNKNVSKALINGIYAVCNLKKVAQAQKELFKAWRFVYFMARLKERHSKFSAELEDVLDKIIDKKTNALYKHSYLAARWAELELRR
>NC_015949.1|WP_014043387.1|2584207_2584618_-|type-III-A-CRISPR-associated-protein-Csm2
MPAQGGNVALSLKNDILSKIETAIDPEKDKDGKAFSDVSEKTGQLLKESGVTVTQIRKVFTEVKRLSPEDDNYKYKLKLLKAKLAYTAGRFNKMKDFQEIINKALPVAEKSPEALNRFKDFFEAAVAYHKYFGGKE
>NC_015949.1|WP_014043386.1|2583352_2584180_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MDVILKGKYIIKCKIEAVTGLHIGEGNNSIEIGGIDNSVVKDAEGKPYIPGSSLKGKMRALMEFAEGKVKDDLMVVAVKKGDKPEICIHMCEDIDCPVCGLFGRNHGKHVTKEEFIRNPNAEGKDFSDAVIPTRLIVRDAKLIDSSITDEMKENLDLEWTEVKFENNIDRITSKATPRQSERVPAGAQFSAEFVVNRYEVDGSDDGQRYLSKFIKAMKLLEDDYLGGQGSRGNGKVKFVDIEIVYKDSSDYEKDSSDLKPIAKADSLDQLKLSTN
>NC_015949.1|WP_014043385.1|2582314_2583325_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MSKGKLYRVSMRFSSPLHIGEKEKIYNITQTFAHSDTLMSGIINAYSLLYGNSSTNELLDGFLRKSPPFEVSSTMPYVQGEFFVPKPAGLNLHHYKDEGKIEVENDKELKKIKFIRENDLLYNFPDKYKAAGSFLLPRDMLYKFVESKKHISLGKVKERARVSIDRLSSSSNIYYFSHFEFEESAGLWFYLRINDQSLEEKIKAAIRLLGDEGLGGDRTCGLGSFEANFEESSMPEENDSAKYYMSLSLVNPQSEDEIKSAISYEILTRSGYIYSKAGLGIKRKALRVFSEGTVFSGKVCGRVVDVTPQKFSQHRVYCFALAFLLPLPEGVMMIGS
>NC_015949.1|WP_014043384.1|2581140_2582325_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MAHEPFESRTYEIEVLTPTIIGGQDKIQSFEFVKDGDYLYFINFDRLLEENLFKESFIDELSRGLSTGDRDFNIKDVLARYNIDFKNSSKYRLKLEGVKRISKEVVPFVKSAGRFYIPGSSLKGAIRSFVTKALNRNFIQLYENDLSSAYQKTLNSADRRNSVDPKYVCKDAEEKIFATPYESPFKHLKISDSDFVSSENAGVYEIKVMNICGGQVKWFAGRSNEDVPDRAVSIIAEGIKPGAKLIGSIKVEKDFVEGNQVVRGIKEKIGVNASATSPTEFLADVLKVVSKDYIQREINFYTRYKQAQIVSEYQKLLNVLNSLDKNQFLIQIGFSTGYLSKTVGIFFNKNHFEKLAKVDRQSKIYPELFPKTRRLVFKNGQVWTVPGWIKVTIK
>NC_015949.1|WP_014043383.1|2580520_2581144_-|hypothetical-protein
MMGCDEKVAKYFTFHFWAREDGVFLPSSYYSKVYEVLKSLLATEQFTISPIKTKNKKEVEDGVWVFEDFRIYLATPFLELFTQNILKIYETLNGLFEGIYLKKISCRSQQPKASGILLSGVFAQKDGVCLEYDRQPEIFSDGLRRQLLNIYYQRFGAYPEDQRFFFVIKDGLKKQHLIRSRIEYFGRYEIFASSELLDMFCQMFCVK
>NC_015949.1|WP_014043382.1|2580256_2580394_-|hypothetical-protein
MSLSALLGASIMMHGLVQGLKVFAVVVVLGFVIKGLWQGFKKELA
>NC_015949.1|WP_014043381.1|2578100_2579951_-|hypothetical-protein
MSKLSQIYGYWKNSIKASMKRYDENMERSLKHLQNFYNMVLKDYIIDWSRYFESQPFRHSLRQKIENFFGKNEINFVAIDGTCVKDEGSDFITFFAGAYGARGKIIIKHEGEKIKYERWDFARDVTMVAQIPVFPYEIEFVASSPELSQMQFYSDKDIQEILNLHTSLMKLAEIYLAYHVVSSSTVDIPQIILLDLAPSTLLRVPYVNYKSTNYLGYKYLNDTIKLSDVIVALSHPYNSLLGVPSRKKYRRYALLLSKLDEVCSQNHKNYFTYKELTEICHLSIEDIKEIVRFLDATGVVEDDEAAGIKLFVNLSQRWSYLVSFFDYICNQIFIRKNPTALEFSNFSEESNIKKLISHDDINFLISIGIRALIEKCWEKNVFLIGIVKDSKSRYFCRNFLNVLSSQNMLGDGKENVDIKNFQIAMSDRLVFENCAALSTELCAPWSSVEFDSAFATLFVDRNNSVTGVKGHIVADDRIFAKSIAQFYLQRSKKQCKMGHAIFVERLLHPSLDRQFLDLVLLENSKLGRLSPFIHLDKKVINWGQAMNIYFLDVLTRNHFPEVIGYPEPLHKADRGAKTLLRFAKGVIHSSQQLYRKDPLNMTFRKFRDKLEFEDEE
>NC_015949.1|WP_014043380.1|2576298_2578095_-|ATP-binding-protein
MFNTEIVGRMMKYDSDIYSRYRAEIWFDYTKKAMNEIKEGALLAVQNFSSTSDKIRYCILEITSVIPLHYGLDNDLSGYPGFLTEAAENIYRDWEEQEEEPLDDATKIRCLAIPTNFEIIIDKDQKVSIGIESNLPMVGAEAFLLDEELTNRILNYDIDKSGDVIEIGHLIRDENVKILLKVEELLRVHFGVFGFTGAGKSNLLSTLVRKILTESNLPVKIVIFDLMGEYSTLLVDLLVKLNNSMIVGIGEKTFVGSLISLMKADRSLPEYKDLLKKATIDVVNSSLYPKGLVSHKDLFKKAFFRILQSRKVKIWQSGDIAVADFAKMYERTLLKGNLGKSEALIKKLYEQLLRKTNPLNATVCLALIQYIENKYLSDEKLGSIARSNLELFVNELKKKYEELKEFGFSNENVIDQKKLIEILNSPDDKALVIFQSHDPDELRNLAYQIGMAIFEDRRRSGKIDPVVSFIFDEADEFIPQDAKDSYERSSEVVMHLARRGRKFGLGIGIATQRITYLNTNIMAQPHTYFVSKLPRKSDQERITDAFGISEDMFKQTFKFKKGCWLLVSYDAIGLEAVPLPIYVQNANDAVLEFLKTLQ
>NC_015949.1|WP_014043391.1|2593065_2594484_-|TIGR01897-family-CRISPR-associated-protein
MKVIYQVGRLDNPAQATKEFYIKNFHGEKVDESGKAELSSIVLRDFLRKRNYEAKTVIVYPVSIVFNSKLPEYIQPEELKNELVDIFKDPSNYLKNPHEFIERIELERNRDEKLIVHSLGEYLGISLDASYDDIVLEILFDMIERYLKGELEELYLDISSGHNIYISAILEAARHFAVFSHLVNWIDDTKSPKIYITFSDPIIGSSAKSFEIHIQQQRFTAFFSSPIKSKEAADYNFSFLREIYPDPNNNSKGSEAVKLKQQAREKRKKLKEKIEMFCLLFSAIKNNVPLYLYSQHYHSADEIKEEIFKLIDHAKARLCSDYQKSPNLNKRAYIDAVLSLGFYIGIVNVLEKYNVTMFCHDTGIDIETVKNSFSEIYLIFRLHTNIVMLGNEVSNTQEKLKQIGDISTWTGLYRIIDPDKSAGEIDPRNFFAHSGFERNATEVRTDDDRVLVRYSLNVNFNDINCWLKRRLE
>NC_015949.1|WP_014043392.1|2594617_2595712_-|DUF1848-domain-containing-protein
MIISASRRTDIPAFFGDWFINRIKEGFAMYRNPMRPTQVFAVSLHPKDVDAIVFWTKNPKNFLDKLKYLDEYIYYFQFTLTPYAQDLEPGIPNKDEVIETFIKLSDMIGKKRVIWRYDPIIITDKMPLDYHKEKFEELCEKLSPYTQKCIISYVDFYSKAEDELNKINAKRLEQDDLYNLFSAVGSIGKKYNLSVETCAEDVPVEYLGLKKAHCVDGDLINELRKEKGFQDKEYRKDNNQRKACGCVQSIDLGIFNTCKHFCVYCYANFSRNSIIKNAQKYDVNSPLLCSALDLEKDEIRIREKDGSKKLEISHILEQDKNQERKISQLDFCVQQINSVEKNTNSSLEKKVLDHIKRIKQRTLL
>NC_015949.1|WP_014043393.1|2595729_2596668_-|hypothetical-protein
MCLLVYDVMRMAKERHSSVCLSSLNSLFQRESNCERCLPNVHFKRKNNGNVRDYDCKNMIYYYCGRYSLKHAGELFTLLQQISHRLPDNPRILSIGCGPCTDLFAFEAYFKTYKPYKKIEYHGLEKNMLWKDIHDFITKHGKKHNLSRFRITYIDVMSEVQKVEEIIKNEKPNIISFQYVLSDMAKYHPVSSVKRFAEEFVQKAFEILPKSTMIVFNDTNVLQRYAERNPDEVKGRDILEPLADKFWHSRNISVFKYYFPYRNDPSLQFGGAHSKCEVDMGNVPADLKNYFEIWYEYRSAQLVLIKNEDILI
>NC_015949.1|WP_014043394.1|2597253_2597460_-|hypothetical-protein
MDIIDENNVDLFQSPKGRLQTIIHTLGLESVSEVSIPNGKATNLPIDDWMIIVEACFNPQREGYKPRR
>NC_015949.1|WP_041725700.1|2599511_2599886_-|hypothetical-protein
MIFEGSAYSGTKQIANIVSKDYSDYQKILWVVSHGYMSLISGNFMPESYVKRRHFAKVLIKLSGDIANLANPEKSTFVDVLKTDFRNYETGNTASSRILCGLIYVLSLRIFIPSILHNYKIFII
>NC_015949.1|WP_167317459.1|2599992_2600193_-|hypothetical-protein
MAAKEIVKNFTHETQSSSEGDYTTFYEEGLAYMYSELEKVKIYYTSAGYTNVTFAVHHLASLMSMK
>NC_015949.1|WP_014043396.1|2600174_2600984_-|hypothetical-protein
MSFWDLLILYVIATSLQPIMKQRMIESARQKLIARIEKKRGSRVILLVHRQETMSFLGFPIYKYIDINDSEEVIRAISMTDPSVPLDIILHTPGGLVLASLQIARAIKRHKGKVTVHVPHHAMSGGTLIALAADEIVMAPDAVLGPVDPQIGEFPAVSILEVVKQKPIADIDDKTLILADVAKKALRQTKDAVLELLSGNYPDDVAENIATQLVEGRWTHDYPITYEKAKELGLKVRCDIDKEIQQLMSLYPQPVVKKSSVEYLWQPRK
>NC_015949.1|WP_014043397.1|2601013_2601742_-|rhomboid-family-intramembrane-serine-protease
MIPLKDTIPSREKPFMTWTLILINVFVFLYQVSMPQEAAQEFVFRYGFVPERFTQLLSHGFVVAASVSIWSIITSMFLHGSWMHLISNMWSLWLFGDNVEDRVGHFRFLIFYILSGFAAALTHWFFNANSPIPTVGASGAISGVMGAYFLMFPLSRIVTLIPLGFIPLFIEIPAIFFLGIWFLSQVSSGILELFGPVFGSGIAWWAHIGGFVFGVLTINMFKKKYRRYRNFFDDEIFYYRYF
>NC_015949.1|WP_014043398.1|2602084_2602594_+|hypothetical-protein
MKKRLLAFLSFVILISFALGVVASSPTNYKALYEKLLKDYNVLKSENQKLKNEVTTLKKKTDDLQKKVTSLPQLSYYDIVVNGVSTAQKVPFISYGGRRYVHFDSMLKTFLNVGDTGYIFNDQTKRVEIGAFVKNKSGIWLSDLQYFDRKGDWSDFGFNATDIMQLILL
>NC_015949.1|WP_083825670.1|2602584_2602935_+|hypothetical-protein
MIVNGKKFYKNIWWKVWGDRKGYKFNLTYKLHGKYKKLQFKYGIHDNSGKGIQAAVRVYGDNEILGEFKTELYDDPGLASINLTGVNYLTLEFETLTYTSDGNRSIITICDPLLIP

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Crispr_ID: NC_015949_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_8

2597265-2599203

TypeIII

Consensus_repeat	Method
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CRISPRCasFinder
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CRT

29 spacers

csx1,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6

The CRISPR arrays of NC_015949_8

>merge|NC_015949|8|2597265-2599203|CRISPRCasFinder,CRT
GTTTGTAGCCTTCCCGTTGGGGATTGAAACAAGCTTCAACTATAATCATCCAGTCATCAATTGGCAAGTTTGTAGCCTTCCCGTTGGGGATTGAAACCTCAGAGACTGATTCCAATCCCAGCGTATGGATTATCGTTTGTAGCCTCCCCTTTGGGGATTGAAACAAGTCAACATTGTTTTCGTCTATGATATCCATCAAGTTTGTAGCCTCCCCTTTGGGGATTGAAACAAAAAGTAGATTGCCCGATGGGGATTGGGCGAAAGGTTTGTAGCCTCCCCTTTGGGGATTGAAACTTCTTCATATTAAATCCGCCTCCTCATTTTATTTTTGTTTGTAGCCTCCCCTTTGGGGATTGAAACAAAAGAAATTCCCCTTGGAGTAGGGCTTGTCCCTACGTTTGTAGCCTCCCCTTTGGGGATTGAAACGCCATGCTATATGCTCAAGGAAAAATGACTGTTATTCGTTTGTAGCCTCCCCTTTGGGGATTGAAACGGAAATACCATGAATTAGGGGCACAGTTACCCAAGCGTTTGTAGCCTCCCCTTTGGGGATTGAAACAGATACTTAGCATACTTAACCTTATTCATCCTTATGTTTGTAGCCTCCCCTTTGGGGATTGAAACCGATTCCCCATCCACTTAAATACTCCCCATCTCTCCAGTTTGTAGCCTCCCCTTTGGGGATTGAAACTACCCTGCCCTGTCCAAAATTTCTTTAGCTGCTTGGTTTGTAGCCTCCCCTTTGGGGATTGAAACTTACTTTGCTGACGAGCATAATTGCAATGTTCATAGTTTGTAGCCTCCCCTTTGGGGATTGAAACTACCACGCACCAAAGCGCTGTAACTTTTACCACTAGTTTGTAGCCTCCCCTTTGGGGATTGAAACCTGTGCTGCCACCAAACTTGATTGAGCATCCCTCAGGTTTGTAGCCTCCCCTTTGGGGATTGAAACAGGGAAGTGATTGATAAATGATAACATCTGTAATAGTTTGTAGCCTCCCCTTTGGGGATTGAAACTTTTAAACCCCAACGGGTAGGCTACTTTTTGCTCTGTTTGTAGCCTCCCCGTTGGGGATTGAAACAGTTATTACAAGATTCTATTATTTTTTTCAATATAAGTTTGTAGCCTCCCCTTTGGGGATTGAAACAATCCTCCTCCTTTTCTGTTTTTTCAAAAGCCTTCACGTTTGTAGCCTCCCCTTTGGGGATTGAAACATCTTCTTCATTCTAAACCCTCCTCCTTATCCTTTTCGTTTGTAGCCTCCCCTTTGGGGATTGAAACGCTTTCTCCACCCTATCCTATGCAGCACATTCTTCCGTTTGTAGCCTCCCCTTTGGGGATTGAAACATGATTTAGCTGATTCGACAGGATTGAGCAAGAAGTTTGTAGCCTCCCCTTTGGGGATTGAAACAAGTAATAAACGTATTTCAAGGGAAGTTCAACCTCGTTTGTAGCCTCCCCTTTGGGGATTGAAACTCAATCCCACTTGGAAGTTTCCACTCGGGAACCCAGTTTGTAGCCTCCCCGTTGGGGATTGAAACTAGACCTTAACCATCATCTCAACAATGTCATCATTGGTTTGTAGCCTCCCCGTTGGGGATTGAAACTTCTTCCTCTAATCCTAAATCATCTAAAAATTTTTTTAGTTTGTAGCCTCCCCGTTGGGGATTGAAACATTTCGTCCTCCCAGGTATTTAGTACCACAAGAGGGTTAGTAGCCTCCCCTTTGGGGATTGAAACTTTCTTTTAGCTGTTGATATCGTGCTAAAATAGATTTAAGTTAGTAGCCTCCCCTTTGGGGATTGAAACCCTTGTGCGTTAGCTCAGTTTGTACCTGCTGAGCTGTTTGTAGCCTCCCCTTTGGGGATTGAAACACCAATTCATCAATACTCATTTTGACTCACCCAGGTTTGTAGCCTTCCCTTTGGGGATTGAGGT

>NC_015949|8|8|2597265-2599203|CRISPRCasFinder
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AAGCTTCAACTATAATCATCCAGTCATCAATTGGCAA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CTCAGAGACTGATTCCAATCCCAGCGTATGGATTATC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAGTCAACATTGTTTTCGTCTATGATATCCATCAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAAAAGTAGATTGCCCGATGGGGATTGGGCGAAAG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTCTTCATATTAAATCCGCCTCCTCATTTTATTTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAAAGAAATTCCCCTTGGAGTAGGGCTTGTCCCTAC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GCCATGCTATATGCTCAAGGAAAAATGACTGTTATTC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GGAAATACCATGAATTAGGGGCACAGTTACCCAAGC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AGATACTTAGCATACTTAACCTTATTCATCCTTAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CGATTCCCCATCCACTTAAATACTCCCCATCTCTCCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TACCCTGCCCTGTCCAAAATTTCTTTAGCTGCTTG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTACTTTGCTGACGAGCATAATTGCAATGTTCATA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TACCACGCACCAAAGCGCTGTAACTTTTACCACTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CTGTGCTGCCACCAAACTTGATTGAGCATCCCTCAG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AGGGAAGTGATTGATAAATGATAACATCTGTAATA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTTTAAACCCCAACGGGTAGGCTACTTTTTGCTCT
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	AGTTATTACAAGATTCTATTATTTTTTTCAATATAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATCCTCCTCCTTTTCTGTTTTTTCAAAAGCCTTCAC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATCTTCTTCATTCTAAACCCTCCTCCTTATCCTTTTC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GCTTTCTCCACCCTATCCTATGCAGCACATTCTTCC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGATTTAGCTGATTCGACAGGATTGAGCAAGAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAGTAATAAACGTATTTCAAGGGAAGTTCAACCTC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TCAATCCCACTTGGAAGTTTCCACTCGGGAACCCA
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TAGACCTTAACCATCATCTCAACAATGTCATCATTG
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TTCTTCCTCTAATCCTAAATCATCTAAAAATTTTTTTA
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	ATTTCGTCCTCCCAGGTATTTAGTACCACAAGAGG
GTTAGTAGCCTCCCCTTTGGGGATTGAAAC	TTTCTTTTAGCTGTTGATATCGTGCTAAAATAGATTTAA
GTTAGTAGCCTCCCCTTTGGGGATTGAAAC	CCTTGTGCGTTAGCTCAGTTTGTACCTGCTGAGCT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACCAATTCATCAATACTCATTTTGACTCACCCAG
GTTTGTAGCCTTCCCTTTGGGGATTGAGGT

>NC_015949|8|7|2597265-2599203|CRT
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	AAGCTTCAACTATAATCATCCAGTCATCAATTGGCAA
GTTTGTAGCCTTCCCGTTGGGGATTGAAAC	CTCAGAGACTGATTCCAATCCCAGCGTATGGATTATC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAGTCAACATTGTTTTCGTCTATGATATCCATCAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAAAAGTAGATTGCCCGATGGGGATTGGGCGAAAG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTCTTCATATTAAATCCGCCTCCTCATTTTATTTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAAAGAAATTCCCCTTGGAGTAGGGCTTGTCCCTAC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GCCATGCTATATGCTCAAGGAAAAATGACTGTTATTC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GGAAATACCATGAATTAGGGGCACAGTTACCCAAGC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AGATACTTAGCATACTTAACCTTATTCATCCTTAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CGATTCCCCATCCACTTAAATACTCCCCATCTCTCCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TACCCTGCCCTGTCCAAAATTTCTTTAGCTGCTTG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTACTTTGCTGACGAGCATAATTGCAATGTTCATA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TACCACGCACCAAAGCGCTGTAACTTTTACCACTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CTGTGCTGCCACCAAACTTGATTGAGCATCCCTCAG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AGGGAAGTGATTGATAAATGATAACATCTGTAATA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTTTAAACCCCAACGGGTAGGCTACTTTTTGCTCT
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	AGTTATTACAAGATTCTATTATTTTTTTCAATATAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATCCTCCTCCTTTTCTGTTTTTTCAAAAGCCTTCAC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATCTTCTTCATTCTAAACCCTCCTCCTTATCCTTTTC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GCTTTCTCCACCCTATCCTATGCAGCACATTCTTCC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGATTTAGCTGATTCGACAGGATTGAGCAAGAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAGTAATAAACGTATTTCAAGGGAAGTTCAACCTC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TCAATCCCACTTGGAAGTTTCCACTCGGGAACCCA
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TAGACCTTAACCATCATCTCAACAATGTCATCATTG
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	TTCTTCCTCTAATCCTAAATCATCTAAAAATTTTTTTA
GTTTGTAGCCTCCCCGTTGGGGATTGAAAC	ATTTCGTCCTCCCAGGTATTTAGTACCACAAGAGG
GTTAGTAGCCTCCCCTTTGGGGATTGAAAC	TTTCTTTTAGCTGTTGATATCGTGCTAAAATAGATTTAA
GTTAGTAGCCTCCCCTTTGGGGATTGAAAC	CCTTGTGCGTTAGCTCAGTTTGTACCTGCTGAGCT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACCAATTCATCAATACTCATTTTGACTCACCCAG
GTTTGTAGCCTTCCCTTTGGGGATTGAGGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_014043387.1\|2584207_2584618_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NC_015949.1\|WP_014043385.1\|2582314_2583325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|273866
NC_015949.1\|WP_014043398.1\|2602084_2602594_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366961
NC_015949.1\|WP_014043386.1\|2583352_2584180_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_015949.1\|WP_014043383.1\|2580520_2581144_-\|hypothetical-protein	cas6	mkCas0062_cas6_CAS-I:CAS-III	unknown
NC_015949.1\|WP_014043393.1\|2595729_2596668_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|381149
NC_015949.1\|WP_083825670.1\|2602584_2602935_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377970
NC_015949.1\|WP_014043396.1\|2600174_2600984_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|110924
NC_015949.1\|WP_014043399.1\|2602967_2603423_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NC_015949.1\|WP_014043388.1\|2584650_2587134_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NC_015949.1\|WP_014043391.1\|2593065_2594484_-\|TIGR01897-family-CRISPR-associated-protein	csx1	cd09728_csx1_CAS-III	gnl\|CDD\|187859
NC_015949.1\|WP_014043389.1\|2590956_2591253_+\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_041725700.1\|2599511_2599886_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043400.1\|2603412_2603685_-\|addiction-module-toxin,-HicA-family	unknown	unknown	gnl\|CDD\|377942
NC_015949.1\|WP_014043392.1\|2594617_2595712_-\|DUF1848-domain-containing-protein	unknown	unknown	gnl\|CDD\|378091
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NC_015949.1\|WP_014043397.1\|2601013_2601742_-\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|223777
NC_015949.1\|WP_167317459.1\|2599992_2600193_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043401.1\|2603930_2604491_+\|biotin-transporter-BioY	unknown	unknown	gnl\|CDD\|376871
NC_015949.1\|WP_014043402.1\|2604785_2605478_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_014043387.1\|2584207_2584618_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	1.09819e-32
NC_015949.1\|WP_014043385.1\|2582314_2583325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	1.20453e-51
NC_015949.1\|WP_014043398.1\|2602084_2602594_+\|hypothetical-protein	gnl\|CDD\|366961	pfam02183, HALZ, Homeobox associated leucine zipper.	7.6091e-05
NC_015949.1\|WP_014043386.1\|2583352_2584180_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	6.51835e-76
NC_015949.1\|WP_014043393.1\|2595729_2596668_-\|hypothetical-protein	gnl\|CDD\|381149	cd19922, REC_RitR-like, receiver (REC) domain of orphan response regulator RitR and similar domains. Streptococcus pneumoniae RitR (Repressor of iron transport Regulator, formerly RR489) is an orphan two-component signal transduction response regulator that is required for lung pathogenicity. It acts to repress iron uptake via binding the pneumococcal iron uptake (Piu) transporter promoter. Members of this subfamily contain REC and DNA-binding output domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays. However, members of this family do not contain the phosphorylatable aspartic acid residue and are phosphorylation-independent.	0.00574532
NC_015949.1\|WP_083825670.1\|2602584_2602935_+\|hypothetical-protein	gnl\|CDD\|377970	pfam08305, NPCBM, NPCBM/NEW2 domain. This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins. This domain has also been called the NEW2 domain (Naumoff DG. Phylogenetic analysis of alpha-galactosidases of the GH27 family. Molecular Biology (Engl Transl). (2004)38:388-399.).	8.2555e-08
NC_015949.1\|WP_014043396.1\|2600174_2600984_-\|hypothetical-protein	gnl\|CDD\|110924	pfam01972, SDH_sah, Serine dehydrogenase proteinase. This family of archaebacterial proteins, formerly known as DUF114, has been found to be a serine dehydrogenase proteinase distantly related to ClpP proteinases that belong to the serine proteinase superfamily. The family has a catalytic triad of Ser, Asp, His residues, which shows an altered residue ordering compared with the ClpP proteinases but similar to that of the carboxypeptidase clan.	8.36863e-114
NC_015949.1\|WP_014043388.1\|2584650_2587134_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	6.95588e-105
NC_015949.1\|WP_014043391.1\|2593065_2594484_-\|TIGR01897-family-CRISPR-associated-protein	gnl\|CDD\|187859	cd09728, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as DxTHG family.	2.6701e-42
NC_015949.1\|WP_014043397.1\|2601013_2601742_-\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	1.41364e-35
NC_015949.1\|WP_014043400.1\|2603412_2603685_-\|addiction-module-toxin,-HicA-family	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	0.000373169
NC_015949.1\|WP_014043392.1\|2594617_2595712_-\|DUF1848-domain-containing-protein	gnl\|CDD\|378091	pfam08902, DUF1848, Domain of unknown function (DUF1848). This family of proteins are functionally uncharacterized. The C-terminus contains a cluster of cysteines that are similar to the iron-sulfur cluster found at the N-terminus of pfam04055.	1.28051e-142
NC_015949.1\|WP_014043384.1\|2581140_2582325_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	4.63196e-24
NC_015949.1\|WP_014043399.1\|2602967_2603423_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	5.5569e-14
NC_015949.1\|WP_014043401.1\|2603930_2604491_+\|biotin-transporter-BioY	gnl\|CDD\|376871	pfam02632, BioY, BioY family. A number of bacterial genes are involved in bioconversion of pimelate into dethiobiotin. BioY is a component of the BioMNY transport system involved in biotin uptake in prokaryotes.	6.0703e-43

>NC_015949.1|WP_014043393.1|2595729_2596668_-|hypothetical-protein
MCLLVYDVMRMAKERHSSVCLSSLNSLFQRESNCERCLPNVHFKRKNNGNVRDYDCKNMIYYYCGRYSLKHAGELFTLLQQISHRLPDNPRILSIGCGPCTDLFAFEAYFKTYKPYKKIEYHGLEKNMLWKDIHDFITKHGKKHNLSRFRITYIDVMSEVQKVEEIIKNEKPNIISFQYVLSDMAKYHPVSSVKRFAEEFVQKAFEILPKSTMIVFNDTNVLQRYAERNPDEVKGRDILEPLADKFWHSRNISVFKYYFPYRNDPSLQFGGAHSKCEVDMGNVPADLKNYFEIWYEYRSAQLVLIKNEDILI
>NC_015949.1|WP_014043392.1|2594617_2595712_-|DUF1848-domain-containing-protein
MIISASRRTDIPAFFGDWFINRIKEGFAMYRNPMRPTQVFAVSLHPKDVDAIVFWTKNPKNFLDKLKYLDEYIYYFQFTLTPYAQDLEPGIPNKDEVIETFIKLSDMIGKKRVIWRYDPIIITDKMPLDYHKEKFEELCEKLSPYTQKCIISYVDFYSKAEDELNKINAKRLEQDDLYNLFSAVGSIGKKYNLSVETCAEDVPVEYLGLKKAHCVDGDLINELRKEKGFQDKEYRKDNNQRKACGCVQSIDLGIFNTCKHFCVYCYANFSRNSIIKNAQKYDVNSPLLCSALDLEKDEIRIREKDGSKKLEISHILEQDKNQERKISQLDFCVQQINSVEKNTNSSLEKKVLDHIKRIKQRTLL
>NC_015949.1|WP_014043391.1|2593065_2594484_-|TIGR01897-family-CRISPR-associated-protein
MKVIYQVGRLDNPAQATKEFYIKNFHGEKVDESGKAELSSIVLRDFLRKRNYEAKTVIVYPVSIVFNSKLPEYIQPEELKNELVDIFKDPSNYLKNPHEFIERIELERNRDEKLIVHSLGEYLGISLDASYDDIVLEILFDMIERYLKGELEELYLDISSGHNIYISAILEAARHFAVFSHLVNWIDDTKSPKIYITFSDPIIGSSAKSFEIHIQQQRFTAFFSSPIKSKEAADYNFSFLREIYPDPNNNSKGSEAVKLKQQAREKRKKLKEKIEMFCLLFSAIKNNVPLYLYSQHYHSADEIKEEIFKLIDHAKARLCSDYQKSPNLNKRAYIDAVLSLGFYIGIVNVLEKYNVTMFCHDTGIDIETVKNSFSEIYLIFRLHTNIVMLGNEVSNTQEKLKQIGDISTWTGLYRIIDPDKSAGEIDPRNFFAHSGFERNATEVRTDDDRVLVRYSLNVNFNDINCWLKRRLE
>NC_015949.1|WP_014043389.1|2590956_2591253_+|hypothetical-protein
MSDIKIIQEDIKHEVAIDIIAGLLGSLTNIKLKTVHSDLDKEIKEQKLQKIEKIRETLCKERDHVYRGDKDAIERALTTYALLYRLIDEEEVINAEVF
>NC_015949.1|WP_014043388.1|2584650_2587134_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MIFYSAHQREEDRNFDYTLFLGAILHDIGKFYMRTENPDAKKNISKEYEAFYQAEGKYAPRHQEWGAFFVEHFLPESLKGVTSLVLYHHRPSSYDQLLISVADKISAKVDRKDISEEEAAGDKSKYLISVLSQISLDRDKKEPKKPFYKLLKKRYDVENPTEGFSSNAKEDYQNLWAEFSRKISILRDGFESSFDLEDFATAVYNLLRLYTYNVPSAFYHSQPDISLWAHSKSTAAIAFCLDRQLKKEFSQENERIRDLEAINTKLLPGNESAIKKGDYPYFCLVKGDVSGIQDFVFDTSMDGALKALKGKSFYISFLLDTIARYILKEENMPVCNLMYNGGGHFYLLMPRYFMEKLSHYQQKIDKILFSAHRGALSVLLEAAEVDLYDFARNFGDCFDRVSRNIQKKKACKLKNVLEETKMKFFEPWEDHDLKCPHCGRKIEPKEDNPDYCRFCDSFVKLGDELMKSLFIVDSWGEEKEFSEFFNIHNVLKAFGRTIEFSNHYESVANTLILDRSRIEDLQIKKKEIERGQKGSKQGFESEFYEDLDISTHVPFKDVNEEVLMLIDDIAESAKGIKTWGIVRGDVDNLGSIFKDGLGKDNSISRVMTLSEEFSLFFGYYFNKLVKKQDGNILVIYAGGDDFCILGQWDVLPQIAHKIYTEFRNFSCHNPDVTLSMGFEIAPDKKYPIYRVAMVCGDHLDQAKEYEREDGKKKDCFAFGANFVGWEEFEDLKKLKEAIADLVGNKNVSKALINGIYAVCNLKKVAQAQKELFKAWRFVYFMARLKERHSKFSAELEDVLDKIIDKKTNALYKHSYLAARWAELELRR
>NC_015949.1|WP_014043387.1|2584207_2584618_-|type-III-A-CRISPR-associated-protein-Csm2
MPAQGGNVALSLKNDILSKIETAIDPEKDKDGKAFSDVSEKTGQLLKESGVTVTQIRKVFTEVKRLSPEDDNYKYKLKLLKAKLAYTAGRFNKMKDFQEIINKALPVAEKSPEALNRFKDFFEAAVAYHKYFGGKE
>NC_015949.1|WP_014043386.1|2583352_2584180_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MDVILKGKYIIKCKIEAVTGLHIGEGNNSIEIGGIDNSVVKDAEGKPYIPGSSLKGKMRALMEFAEGKVKDDLMVVAVKKGDKPEICIHMCEDIDCPVCGLFGRNHGKHVTKEEFIRNPNAEGKDFSDAVIPTRLIVRDAKLIDSSITDEMKENLDLEWTEVKFENNIDRITSKATPRQSERVPAGAQFSAEFVVNRYEVDGSDDGQRYLSKFIKAMKLLEDDYLGGQGSRGNGKVKFVDIEIVYKDSSDYEKDSSDLKPIAKADSLDQLKLSTN
>NC_015949.1|WP_014043385.1|2582314_2583325_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MSKGKLYRVSMRFSSPLHIGEKEKIYNITQTFAHSDTLMSGIINAYSLLYGNSSTNELLDGFLRKSPPFEVSSTMPYVQGEFFVPKPAGLNLHHYKDEGKIEVENDKELKKIKFIRENDLLYNFPDKYKAAGSFLLPRDMLYKFVESKKHISLGKVKERARVSIDRLSSSSNIYYFSHFEFEESAGLWFYLRINDQSLEEKIKAAIRLLGDEGLGGDRTCGLGSFEANFEESSMPEENDSAKYYMSLSLVNPQSEDEIKSAISYEILTRSGYIYSKAGLGIKRKALRVFSEGTVFSGKVCGRVVDVTPQKFSQHRVYCFALAFLLPLPEGVMMIGS
>NC_015949.1|WP_014043384.1|2581140_2582325_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MAHEPFESRTYEIEVLTPTIIGGQDKIQSFEFVKDGDYLYFINFDRLLEENLFKESFIDELSRGLSTGDRDFNIKDVLARYNIDFKNSSKYRLKLEGVKRISKEVVPFVKSAGRFYIPGSSLKGAIRSFVTKALNRNFIQLYENDLSSAYQKTLNSADRRNSVDPKYVCKDAEEKIFATPYESPFKHLKISDSDFVSSENAGVYEIKVMNICGGQVKWFAGRSNEDVPDRAVSIIAEGIKPGAKLIGSIKVEKDFVEGNQVVRGIKEKIGVNASATSPTEFLADVLKVVSKDYIQREINFYTRYKQAQIVSEYQKLLNVLNSLDKNQFLIQIGFSTGYLSKTVGIFFNKNHFEKLAKVDRQSKIYPELFPKTRRLVFKNGQVWTVPGWIKVTIK
>NC_015949.1|WP_014043383.1|2580520_2581144_-|hypothetical-protein
MMGCDEKVAKYFTFHFWAREDGVFLPSSYYSKVYEVLKSLLATEQFTISPIKTKNKKEVEDGVWVFEDFRIYLATPFLELFTQNILKIYETLNGLFEGIYLKKISCRSQQPKASGILLSGVFAQKDGVCLEYDRQPEIFSDGLRRQLLNIYYQRFGAYPEDQRFFFVIKDGLKKQHLIRSRIEYFGRYEIFASSELLDMFCQMFCVK
>NC_015949.1|WP_041725700.1|2599511_2599886_-|hypothetical-protein
MIFEGSAYSGTKQIANIVSKDYSDYQKILWVVSHGYMSLISGNFMPESYVKRRHFAKVLIKLSGDIANLANPEKSTFVDVLKTDFRNYETGNTASSRILCGLIYVLSLRIFIPSILHNYKIFII
>NC_015949.1|WP_167317459.1|2599992_2600193_-|hypothetical-protein
MAAKEIVKNFTHETQSSSEGDYTTFYEEGLAYMYSELEKVKIYYTSAGYTNVTFAVHHLASLMSMK
>NC_015949.1|WP_014043396.1|2600174_2600984_-|hypothetical-protein
MSFWDLLILYVIATSLQPIMKQRMIESARQKLIARIEKKRGSRVILLVHRQETMSFLGFPIYKYIDINDSEEVIRAISMTDPSVPLDIILHTPGGLVLASLQIARAIKRHKGKVTVHVPHHAMSGGTLIALAADEIVMAPDAVLGPVDPQIGEFPAVSILEVVKQKPIADIDDKTLILADVAKKALRQTKDAVLELLSGNYPDDVAENIATQLVEGRWTHDYPITYEKAKELGLKVRCDIDKEIQQLMSLYPQPVVKKSSVEYLWQPRK
>NC_015949.1|WP_014043397.1|2601013_2601742_-|rhomboid-family-intramembrane-serine-protease
MIPLKDTIPSREKPFMTWTLILINVFVFLYQVSMPQEAAQEFVFRYGFVPERFTQLLSHGFVVAASVSIWSIITSMFLHGSWMHLISNMWSLWLFGDNVEDRVGHFRFLIFYILSGFAAALTHWFFNANSPIPTVGASGAISGVMGAYFLMFPLSRIVTLIPLGFIPLFIEIPAIFFLGIWFLSQVSSGILELFGPVFGSGIAWWAHIGGFVFGVLTINMFKKKYRRYRNFFDDEIFYYRYF
>NC_015949.1|WP_014043398.1|2602084_2602594_+|hypothetical-protein
MKKRLLAFLSFVILISFALGVVASSPTNYKALYEKLLKDYNVLKSENQKLKNEVTTLKKKTDDLQKKVTSLPQLSYYDIVVNGVSTAQKVPFISYGGRRYVHFDSMLKTFLNVGDTGYIFNDQTKRVEIGAFVKNKSGIWLSDLQYFDRKGDWSDFGFNATDIMQLILL
>NC_015949.1|WP_083825670.1|2602584_2602935_+|hypothetical-protein
MIVNGKKFYKNIWWKVWGDRKGYKFNLTYKLHGKYKKLQFKYGIHDNSGKGIQAAVRVYGDNEILGEFKTELYDDPGLASINLTGVNYLTLEFETLTYTSDGNRSIITICDPLLIP
>NC_015949.1|WP_014043399.1|2602967_2603423_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MDYKVEIIKLSEEDGGGYIAIVPKLPGCISDGNTPQEALENVQDAIKCWIETAKEKGLPIPSPEEYKEDYKEEYSGRLVLRIPKSLHKRLAQEAKKEGVSLNSFIQHLISYALGCRDNDLSKMLKQPYIIPPVISEDLNILESGEKRKTKT
>NC_015949.1|WP_014043400.1|2603412_2603685_-|addiction-module-toxin,-HicA-family
MSHIEKLLKNLEENPKHVSFTDLDKILKYFGFERREPKGGSSHVTYSHPLLTEILTIPKGSKHVKPIYAKKALKLINELKNNFGSDKNGL
>NC_015949.1|WP_014043401.1|2603930_2604491_+|biotin-transporter-BioY
MENVKSLHTTKMLVLSALFTAIVAVCAQVSIPIGPVPFTLQVLAIFLASLVLPPKYAFLSLLVYDLLGAVGVPVFAGFTGGLSKFVGPTGGYLMAFPIAAFVTSYINTKKPIKNEAANASVALILGLAIIYIFGFLYLSWAAHMTLKKAFAAGVLPFIIPDIIKLAIAYLLASFLKSRKVLSIVQN
>NC_015949.1|WP_014043402.1|2604785_2605478_+|hypothetical-protein
MKKRIIFYFCVLITITIVVVYIYNVLHKHPTSRDYIYMAGMRSASLIEINTEEIYGLLPQNLNNFENWFTNDKLEKLYIYYNNLSYTLDTFLFLNSSLNSNYLHFCRKIRPLYDNIFYLILYSSHDSKDLYMIRVNGIPIQVKSFYQKYAIEKQKINKYDEEYYQYLRQLLVRITDQVFEVKYYGDTKTYPIFLKKELPKILDLEKEFNKKTEEYLKKIGLYDKYAKQQE

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Crispr_ID: NC_015949_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_9

2612217-2616136

TypeI-B,TypeIII-A?

Consensus_repeat	Method
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	PILER-CR
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CRISPRCasFinder
GTTTGTAGCCTNCCCTTTGGGGATTGAAAC	CRT

58 spacers

csx20,cas4,cas1,cas2,cas8b1,cas7,cas5,cas3,csm6

The CRISPR arrays of NC_015949_9

>merge|NC_015949|9|2612217-2616136|PILER-CR,CRISPRCasFinder,CRT
GTTTGTAGCCTCCCCTTTGGGGATTGAAACTAAGGGAAAACTAACGATTTAACAAGAGCAGGATGTCCGTTTGTAGCCTCCCCTTTGGGGATTGAAACAAAAATCCGAGTATGAAGAAAAAATAAAGTCGTTTGTGTTTGTAGCCTCCCCTTTGGGGATTGAAACATTTTATTTGCATCTGCGGTTTTTAACCATGAATGAATGTTTGTAGCCTCCCCTTTGGGGATTGAAACACCGCCCCGATGATAATTCCCTCATCGGGAAAGTCAGTTTGTAGCCTCCCCTTTGGGGATTGAAACCTGTTTAATGCATGCCATGTAGTTTCTATCCACATGTTTGTAGCCTCCCCTTTGGGGATTGAAACATATTTACTTTTGCCTTTTCTGTCTCAGCTTTCAAAAGTTTGTAGCCTCCCCTTTGGGGATTGAAACATGAAAAACATTAATTACATTCTTGCAAGGGATGAAGTTTGTAGCCTCCCCTTTGGGGATTGAAACAAGAGACGAGTATTGGACTTGCAAAGAAATTGTATCGTGTTTGTAGCCTCCCCTTTGGGGATTGAAACAATAATTTCTAAATATTCTTAATCTATCTCAAAAGAGTTTGTAGCCTCCCCTTTGGGGATTGAAACATGAACTTCTTCAAAAATTTCTAAATACTTTCAATGTTTGTAGCCTCCCCTTTGGGGATTGAAACATCTATACCCTTACTCTTCAATATGCTGAACTCATCTGTTTGTAGCCTCCCCTTTGGGGATTGAAACTGCTCAGATAGACGAAGCAGATTATATTTGTAAGCGTTTGTAGCCTCCCCTTTGGGGATTGAAACGCTTTGAAATTGCCGTCTTTGTCTTTTTCGAGCTCAGTTTGTAGCCTCCCCTTTGGGGATTGAAACGTACTTCAAACGTCCAAGCGATAATGTGAGCTTGCACATGTTTGTAGCCTCCCCTTTGGGGATTGAAACTGTGATTGCAATTGCTCTTGTATCTTTGATTCAATCTGTTTGTAGCCTCCCCTTTGGGGATTGAAACCCACCACGTACTAATGATTGATTGATAGTACGAATGTTTGTAGCCTCCCCTTTGGGGATTGAAACTTTTTTCACCTCCCCTTGGACACGATGGCTACTACGTTTGTAGCCTCCCCTTTGGGGATTGAAACATAAGTTCTCCACAGACAGGACAGGTGGCTAATTCCCGGTTTGTAGCCTCCCCTTTGGGGATTGAAACTACCACCGCCTTACGGTGTTAATTGTAGTTTACCACTTCGTTTGTAGCCTCCCCTTTGGGGATTGAAACGTCATTGATGCGTGGTGGAGAACAGTTCGTTGTCTTTGTTTGTAGCCTCCCCTTTGGGGATTGAAACAATGGCTGAAAAGGTAAGCAACAAGCCGTGGGGTGCCGTTTGTAGCCTCCCCTTTGGGGATTGAAACTGGCATTGTGGAGATGGACGTGGCAGATATGGTATAAGTTTGTAGCCTCCCCTTTGGGGATTGAAACTGTTTTCTTGCTTTATCAACTCTGCAAGCTTTCTATTAGTTTGTAGCCTCCCCTTTGGGGATTGAAACTTCTGAGAGTGAAAGGTGATTCAATGGAGCCAGAGATAGTTTGTAGCCTCCCCTTTGGGGATTGAAACCCCTATCTGTTCAATTGTTAAAGTCTCATCTTCAACGTTTGTAGCCTCCCCTTTGGGGATTGAAACATGAATGTTTCAAACACATAGCGTTCCCAGTCCTCAAGGTTTGTAGCCTCCCCTTTGGGGATTGAAACAATTATTGTCCAAGATTTTAATAATTCATATTTTATGTTTGTAGCCTCCCCTTTGGGGATTGAAACACCTGAACTGCCAACGTTGCATACCCAGCTTTTTTAGTTTGTAGCCTCCCCTTTGGGGATTGAAACACTGAATAATACACTGTCGCCCTTGTGCCTTCTATTAGTTTGTAGCCTCCCCTTTGGGGATTGAAACTATCTTATTCCATCATACTCTACCTGAACTGCCAACGTGTTTGTAGCCTCCCCTTTGGGGATTGAAACAGAGGTAGACGACATATTTAGACTTGTATTGATGTTAGGTTTGTAGCCTCCCCTTTGGGGATTGAAACCTACCACCATTATTACTACCTGCACTATAATTTGGTGTTTGTAGCCTCCCCTTTGGGGATTGAAACGTCTCAGGTTGTGTTACAAGTATGTTATAAAAATCTTTGTTTGTAGCCTCCCCTTTGGGGATTGAAACACAGTTGACCTTTTTTGATTGAAAAGAGGTGATGAAGTTTGTAGCCTCCCCTTTGGGGATTGAAACTTAATGCTTGATGGTGAGAAATCACGGTTTTTCAGTTGTTTGTAGCCTGCCCTTTGGGGATTGAAACCACGATATCCTTTCAAACCTTCACCATCTGTTTTCAACGTTTGTAGCCTGCCCTTTGGGGATTGAAACGCAAGTATCTCATACAGGATAGTGCTCGCAGTGCGAGTTTGTAGCCTGCCCTTTGGGGATTGAAACATGATTTTTATGATAGAGTTGCGTTTGAAGATGTAAAAGTTTGTAGCCTGCCCTTTGGGGATTGAAACTAATATATATTTTACACCATAATAGCTTTTTCCTGCTCGTTTGTAGCCTGCCCTTTGGGGATTGAAACAAGTCTTCGCTATCATTGATACTGGTATCAGTGTTAGTTTGTAGCCTGCCCTTTGGGGATTGAAACACTCTATAATGTCTACTCAATACAAGTGCATCAAAAAGGTTTGTAGCCTGCCCTTTGGGGATTGAAACGCAGGATGTGCCAGGTACCGTATGCACGGTACGCAGTAGTTTGTAGCCTGCCCTTTGGGGATTGAAACTGTCTAAATCATCAGCAAGTTTTCTAAAATCATTTGCATGTTTGTAGCCTGCCCTTTGGGGATTGAAACTAGTCAGGATAATTCAATTGCGAATAAGCATAGTTTGTTTGTAGCCTCCCCTTTGGGGATTGAAACTCCTGTTGGCAAACTTTTGCAAATCCCCATAATCGGCAGTTTGTAGCCTCCCCTTTGGGGATTGAAACATTATCCTTGCCATCCTATCAATTTCGAAATCTATTGTTTGTAGCCTCCCCTTTGGGGATTGAAACATTGAAGCACAAATTAAAGCCTGCAAAGAATACTGCGTTTGTAGCCTCCCCTTTGGGGATTGAAACGCTTTTCCTAAATTCTAATGGGGACTCTGTCCCCATAGTTTGTAGCCTCCCCTTTGGGGATTGAAACGTCAATTTCTGATCCCTTGGTAAACATACTGGTCTACTAGTTTGTAGCCTCCCCTTTGGGGATTGAAACACTACTTTAGAAATTATGAATTTTCTGTCATTGATAAGTTTGTAGCCTGCCCTTTGGGGATTGAAACTTATAAATCTTGCGTGAAGTGTTTGGTGAATGCATGTTTGTAGCCTGCCCTTTGGGGATTGAAACGCTATAATGTCAAAATCAGGAATTTCTTTTTTAAGTTCGTTTGTAGCCTGCCCTTTGGGGATTGAAACACAACACAGAAGTGCCTGCAACAAACGTTTCAGTAGGTTTGTAGCCTGCCCTTTGGGGATTGAAACACAAGCACTTTCTTCATACCAATCTACCTCCAATTTTGTTTGTAGCCTGCCCTTTGGGGATTGAAACTAAACTATGATTGCTTTTTCATATTCTCTTATTTCTTTGTTTGTAGCCTGCCCTTTGGGGATTGAAACGCTTGTTAGAATATCAGCAAACAAGAGCAAAAATCAGTTTGTAGCCTGCCCTTTGGGGATTGAAACATGAATAAGTATTTGGGTTTATTTTCTTTTTTTGGCTTTTGTTTGTAGCCTGCCCTTTGGGGATTGAAATATTCCTCTTTTTGGTGATTTTTGTACTCTTCTTGAAGTTTGTTTGTAGCCTTCCCGTTGGGGATTGAGAA

>NC_015949|9|7|2612217-2616066|PILER-CR
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TAAGGGAAAACTAACGATTTAACAAGAGCAGGATGTCC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAAAATCCGAGTATGAAGAAAAAATAAAGTCGTTTGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATTTTATTTGCATCTGCGGTTTTTAACCATGAATGAAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACCGCCCCGATGATAATTCCCTCATCGGGAAAGTCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CTGTTTAATGCATGCCATGTAGTTTCTATCCACAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATATTTACTTTTGCCTTTTCTGTCTCAGCTTTCAAAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGAAAAACATTAATTACATTCTTGCAAGGGATGAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAGAGACGAGTATTGGACTTGCAAAGAAATTGTATCGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATAATTTCTAAATATTCTTAATCTATCTCAAAAGA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGAACTTCTTCAAAAATTTCTAAATACTTTCAAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATCTATACCCTTACTCTTCAATATGCTGAACTCATCT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGCTCAGATAGACGAAGCAGATTATATTTGTAAGC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GCTTTGAAATTGCCGTCTTTGTCTTTTTCGAGCTCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTACTTCAAACGTCCAAGCGATAATGTGAGCTTGCACAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGTGATTGCAATTGCTCTTGTATCTTTGATTCAATCT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CCACCACGTACTAATGATTGATTGATAGTACGAAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTTTTTCACCTCCCCTTGGACACGATGGCTACTAC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATAAGTTCTCCACAGACAGGACAGGTGGCTAATTCCCG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TACCACCGCCTTACGGTGTTAATTGTAGTTTACCACTTC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTCATTGATGCGTGGTGGAGAACAGTTCGTTGTCTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATGGCTGAAAAGGTAAGCAACAAGCCGTGGGGTGCC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGGCATTGTGGAGATGGACGTGGCAGATATGGTATAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGTTTTCTTGCTTTATCAACTCTGCAAGCTTTCTATTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTCTGAGAGTGAAAGGTGATTCAATGGAGCCAGAGATA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CCCTATCTGTTCAATTGTTAAAGTCTCATCTTCAAC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGAATGTTTCAAACACATAGCGTTCCCAGTCCTCAAG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATTATTGTCCAAGATTTTAATAATTCATATTTTAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACCTGAACTGCCAACGTTGCATACCCAGCTTTTTTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACTGAATAATACACTGTCGCCCTTGTGCCTTCTATTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TATCTTATTCCATCATACTCTACCTGAACTGCCAACGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AGAGGTAGACGACATATTTAGACTTGTATTGATGTTAG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CTACCACCATTATTACTACCTGCACTATAATTTGGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTCTCAGGTTGTGTTACAAGTATGTTATAAAAATCTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACAGTTGACCTTTTTTGATTGAAAAGAGGTGATGAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTAATGCTTGATGGTGAGAAATCACGGTTTTTCAGTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	CACGATATCCTTTCAAACCTTCACCATCTGTTTTCAAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCAAGTATCTCATACAGGATAGTGCTCGCAGTGCGA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATGATTTTTATGATAGAGTTGCGTTTGAAGATGTAAAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAATATATATTTTACACCATAATAGCTTTTTCCTGCTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AAGTCTTCGCTATCATTGATACTGGTATCAGTGTTA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACTCTATAATGTCTACTCAATACAAGTGCATCAAAAAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCAGGATGTGCCAGGTACCGTATGCACGGTACGCAGTA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TGTCTAAATCATCAGCAAGTTTTCTAAAATCATTTGCAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAGTCAGGATAATTCAATTGCGAATAAGCATAGTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TCCTGTTGGCAAACTTTTGCAAATCCCCATAATCGGCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATTATCCTTGCCATCCTATCAATTTCGAAATCTATT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATTGAAGCACAAATTAAAGCCTGCAAAGAATACTGC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GCTTTTCCTAAATTCTAATGGGGACTCTGTCCCCATA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTCAATTTCTGATCCCTTGGTAAACATACTGGTCTACTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACTACTTTAGAAATTATGAATTTTCTGTCATTGATAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTATAAATCTTGCGTGAAGTGTTTGGTGAATGCAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTATAATGTCAAAATCAGGAATTTCTTTTTTAAGTTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACAACACAGAAGTGCCTGCAACAAACGTTTCAGTAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACAAGCACTTTCTTCATACCAATCTACCTCCAATTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAAACTATGATTGCTTTTTCATATTCTCTTATTTCTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTTGTTAGAATATCAGCAAACAAGAGCAAAAATCA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATGAATAAGTATTTGGGTTTATTTTCTTTTTTTGGCTTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAT

>NC_015949|9|9|2612217-2616136|CRISPRCasFinder
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TAAGGGAAAACTAACGATTTAACAAGAGCAGGATGTCC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAAAATCCGAGTATGAAGAAAAAATAAAGTCGTTTGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATTTTATTTGCATCTGCGGTTTTTAACCATGAATGAAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACCGCCCCGATGATAATTCCCTCATCGGGAAAGTCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CTGTTTAATGCATGCCATGTAGTTTCTATCCACAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATATTTACTTTTGCCTTTTCTGTCTCAGCTTTCAAAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGAAAAACATTAATTACATTCTTGCAAGGGATGAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAGAGACGAGTATTGGACTTGCAAAGAAATTGTATCGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATAATTTCTAAATATTCTTAATCTATCTCAAAAGA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGAACTTCTTCAAAAATTTCTAAATACTTTCAAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATCTATACCCTTACTCTTCAATATGCTGAACTCATCT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGCTCAGATAGACGAAGCAGATTATATTTGTAAGC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GCTTTGAAATTGCCGTCTTTGTCTTTTTCGAGCTCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTACTTCAAACGTCCAAGCGATAATGTGAGCTTGCACAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGTGATTGCAATTGCTCTTGTATCTTTGATTCAATCT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CCACCACGTACTAATGATTGATTGATAGTACGAAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTTTTTCACCTCCCCTTGGACACGATGGCTACTAC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATAAGTTCTCCACAGACAGGACAGGTGGCTAATTCCCG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TACCACCGCCTTACGGTGTTAATTGTAGTTTACCACTTC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTCATTGATGCGTGGTGGAGAACAGTTCGTTGTCTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATGGCTGAAAAGGTAAGCAACAAGCCGTGGGGTGCC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGGCATTGTGGAGATGGACGTGGCAGATATGGTATAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGTTTTCTTGCTTTATCAACTCTGCAAGCTTTCTATTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTCTGAGAGTGAAAGGTGATTCAATGGAGCCAGAGATA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CCCTATCTGTTCAATTGTTAAAGTCTCATCTTCAAC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGAATGTTTCAAACACATAGCGTTCCCAGTCCTCAAG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATTATTGTCCAAGATTTTAATAATTCATATTTTAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACCTGAACTGCCAACGTTGCATACCCAGCTTTTTTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACTGAATAATACACTGTCGCCCTTGTGCCTTCTATTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TATCTTATTCCATCATACTCTACCTGAACTGCCAACGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AGAGGTAGACGACATATTTAGACTTGTATTGATGTTAG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CTACCACCATTATTACTACCTGCACTATAATTTGGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTCTCAGGTTGTGTTACAAGTATGTTATAAAAATCTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACAGTTGACCTTTTTTGATTGAAAAGAGGTGATGAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTAATGCTTGATGGTGAGAAATCACGGTTTTTCAGTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	CACGATATCCTTTCAAACCTTCACCATCTGTTTTCAAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCAAGTATCTCATACAGGATAGTGCTCGCAGTGCGA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATGATTTTTATGATAGAGTTGCGTTTGAAGATGTAAAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAATATATATTTTACACCATAATAGCTTTTTCCTGCTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AAGTCTTCGCTATCATTGATACTGGTATCAGTGTTA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACTCTATAATGTCTACTCAATACAAGTGCATCAAAAAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCAGGATGTGCCAGGTACCGTATGCACGGTACGCAGTA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TGTCTAAATCATCAGCAAGTTTTCTAAAATCATTTGCAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAGTCAGGATAATTCAATTGCGAATAAGCATAGTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TCCTGTTGGCAAACTTTTGCAAATCCCCATAATCGGCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATTATCCTTGCCATCCTATCAATTTCGAAATCTATT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATTGAAGCACAAATTAAAGCCTGCAAAGAATACTGC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GCTTTTCCTAAATTCTAATGGGGACTCTGTCCCCATA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTCAATTTCTGATCCCTTGGTAAACATACTGGTCTACTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACTACTTTAGAAATTATGAATTTTCTGTCATTGATAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTATAAATCTTGCGTGAAGTGTTTGGTGAATGCAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTATAATGTCAAAATCAGGAATTTCTTTTTTAAGTTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACAACACAGAAGTGCCTGCAACAAACGTTTCAGTAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACAAGCACTTTCTTCATACCAATCTACCTCCAATTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAAACTATGATTGCTTTTTCATATTCTCTTATTTCTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTTGTTAGAATATCAGCAAACAAGAGCAAAAATCA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATGAATAAGTATTTGGGTTTATTTTCTTTTTTTGGCTTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAT	ATTCCTCTTTTTGGTGATTTTTGTACTCTTCTTGAAGTTT
GTTTGTAGCCTTCCCGTTGGGGATTGAGAA

>NC_015949|9|8|2612217-2616136|CRT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TAAGGGAAAACTAACGATTTAACAAGAGCAGGATGTCC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAAAATCCGAGTATGAAGAAAAAATAAAGTCGTTTGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATTTTATTTGCATCTGCGGTTTTTAACCATGAATGAAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACCGCCCCGATGATAATTCCCTCATCGGGAAAGTCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CTGTTTAATGCATGCCATGTAGTTTCTATCCACAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATATTTACTTTTGCCTTTTCTGTCTCAGCTTTCAAAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGAAAAACATTAATTACATTCTTGCAAGGGATGAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AAGAGACGAGTATTGGACTTGCAAAGAAATTGTATCGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATAATTTCTAAATATTCTTAATCTATCTCAAAAGA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGAACTTCTTCAAAAATTTCTAAATACTTTCAAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATCTATACCCTTACTCTTCAATATGCTGAACTCATCT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGCTCAGATAGACGAAGCAGATTATATTTGTAAGC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GCTTTGAAATTGCCGTCTTTGTCTTTTTCGAGCTCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTACTTCAAACGTCCAAGCGATAATGTGAGCTTGCACAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGTGATTGCAATTGCTCTTGTATCTTTGATTCAATCT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CCACCACGTACTAATGATTGATTGATAGTACGAAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTTTTTCACCTCCCCTTGGACACGATGGCTACTAC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATAAGTTCTCCACAGACAGGACAGGTGGCTAATTCCCG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TACCACCGCCTTACGGTGTTAATTGTAGTTTACCACTTC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTCATTGATGCGTGGTGGAGAACAGTTCGTTGTCTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATGGCTGAAAAGGTAAGCAACAAGCCGTGGGGTGCC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGGCATTGTGGAGATGGACGTGGCAGATATGGTATAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TGTTTTCTTGCTTTATCAACTCTGCAAGCTTTCTATTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTCTGAGAGTGAAAGGTGATTCAATGGAGCCAGAGATA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CCCTATCTGTTCAATTGTTAAAGTCTCATCTTCAAC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATGAATGTTTCAAACACATAGCGTTCCCAGTCCTCAAG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AATTATTGTCCAAGATTTTAATAATTCATATTTTAT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACCTGAACTGCCAACGTTGCATACCCAGCTTTTTTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACTGAATAATACACTGTCGCCCTTGTGCCTTCTATTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TATCTTATTCCATCATACTCTACCTGAACTGCCAACGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	AGAGGTAGACGACATATTTAGACTTGTATTGATGTTAG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	CTACCACCATTATTACTACCTGCACTATAATTTGGT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTCTCAGGTTGTGTTACAAGTATGTTATAAAAATCTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACAGTTGACCTTTTTTGATTGAAAAGAGGTGATGAA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TTAATGCTTGATGGTGAGAAATCACGGTTTTTCAGTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	CACGATATCCTTTCAAACCTTCACCATCTGTTTTCAAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCAAGTATCTCATACAGGATAGTGCTCGCAGTGCGA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATGATTTTTATGATAGAGTTGCGTTTGAAGATGTAAAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAATATATATTTTACACCATAATAGCTTTTTCCTGCTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AAGTCTTCGCTATCATTGATACTGGTATCAGTGTTA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACTCTATAATGTCTACTCAATACAAGTGCATCAAAAAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCAGGATGTGCCAGGTACCGTATGCACGGTACGCAGTA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TGTCTAAATCATCAGCAAGTTTTCTAAAATCATTTGCAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAGTCAGGATAATTCAATTGCGAATAAGCATAGTTT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	TCCTGTTGGCAAACTTTTGCAAATCCCCATAATCGGCA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATTATCCTTGCCATCCTATCAATTTCGAAATCTATT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ATTGAAGCACAAATTAAAGCCTGCAAAGAATACTGC
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GCTTTTCCTAAATTCTAATGGGGACTCTGTCCCCATA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	GTCAATTTCTGATCCCTTGGTAAACATACTGGTCTACTA
GTTTGTAGCCTCCCCTTTGGGGATTGAAAC	ACTACTTTAGAAATTATGAATTTTCTGTCATTGATAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTATAAATCTTGCGTGAAGTGTTTGGTGAATGCAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTATAATGTCAAAATCAGGAATTTCTTTTTTAAGTTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACAACACAGAAGTGCCTGCAACAAACGTTTCAGTAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACAAGCACTTTCTTCATACCAATCTACCTCCAATTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAAACTATGATTGCTTTTTCATATTCTCTTATTTCTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTTGTTAGAATATCAGCAAACAAGAGCAAAAATCA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATGAATAAGTATTTGGGTTTATTTTCTTTTTTTGGCTTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAT	ATTCCTCTTTTTGGTGATTTTTGTACTCTTCTTGAAGTTT
GTTTGTAGCCTTCCCGTTGGGGATTGAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_049783163.1\|2610945_2611263_+\|stage-V-sporulation-protein-AE	unknown	unknown	gnl\|CDD\|131886
NC_015949.1\|WP_041725840.1\|2625756_2627148_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224586
NC_015949.1\|WP_013433703.1\|2608682_2608895_-\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NC_015949.1\|WP_014043404.1\|2609373_2609832_+\|stage-V-sporulation-protein-AC	unknown	unknown	gnl\|CDD\|131885
NC_015949.1\|WP_013433712.1\|2617314_2618310_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NC_015949.1\|WP_014043407.1\|2611321_2611729_-\|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_015949.1\|WP_013433710.1\|2616286_2616667_+\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043402.1\|2604785_2605478_+\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_013404408.1\|2608420_2608570_-\|YvrJ-family-protein	unknown	unknown	gnl\|CDD\|378969
NC_015949.1\|WP_014043408.1\|2618325_2618589_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015949.1\|WP_014043403.1\|2605560_2607774_-\|ATP-dependent-RecD-like-DNA-helicase	unknown	unknown	gnl\|CDD\|273632
NC_015949.1\|WP_013433704.1\|2608952_2609165_-\|DUF1659-domain-containing-protein	unknown	unknown	gnl\|CDD\|377933
NC_015949.1\|WP_013433714.1\|2618665_2620588_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_015949.1\|WP_013433711.1\|2616814_2617318_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_015949.1\|WP_013433702.1\|2607823_2608336_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_013433715.1\|2620652_2621633_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|187821
NC_015949.1\|WP_014043410.1\|2622361_2624830_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_015949.1\|WP_014043405.1\|2609850_2610861_+\|stage-V-sporulation-protein-AD	unknown	unknown	gnl\|CDD\|236230
NC_015949.1\|WP_014043409.1\|2621655_2622387_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl\|CDD\|187873

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_049783163.1\|2610945_2611263_+\|stage-V-sporulation-protein-AE	gnl\|CDD\|131886	TIGR02839, stage_V_sporulation_protein_AE, stage V sporulation protein AE. This model describes stage V sporulation protein AE, a paralog of stage V sporulation protein AC. Both are proteins found to present in a species if and only if that species is one of the Firmicutes capable of endospore formation, as of the time of the publication of the genome of Carboxydothermus hydrogenoformans. Mutants in spoVAE have a stage V sproulation defect. [Cellular processes, Sporulation and germination].	2.99454e-42
NC_015949.1\|WP_041725840.1\|2625756_2627148_-\|ATP-binding-protein	gnl\|CDD\|224586	COG1672, COG1672, Predicted ATPase (AAA+ superfamily) [General function prediction only].	2.46699e-30
NC_015949.1\|WP_013433703.1\|2608682_2608895_-\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	2.84865e-22
NC_015949.1\|WP_014043404.1\|2609373_2609832_+\|stage-V-sporulation-protein-AC	gnl\|CDD\|131885	TIGR02838, stage_V_sporulation_protein_AC, stage V sporulation protein AC. This model describes stage V sporulation protein AC, a paralog of stage V sporulation protein AE. Both are proteins found to present in a species if and only if that species is one of the Firmicutes capable of endospore formation, as of the time of the publication of the genome of Carboxydothermus hydrogenoformans. Mutants in spoVAC have a stage V sproulation defect. [Cellular processes, Sporulation and germination].	1.80319e-64
NC_015949.1\|WP_013433712.1\|2617314_2618310_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	5.1355e-168
NC_015949.1\|WP_014043410.1\|2622361_2624830_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	5.6921e-52
NC_015949.1\|WP_014043408.1\|2618325_2618589_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.87467e-29
NC_015949.1\|WP_013404408.1\|2608420_2608570_-\|YvrJ-family-protein	gnl\|CDD\|378969	pfam12841, YvrJ, YvrJ protein family. This family of short proteins are related to B. subtilis YvrJ protein. None of the members of this family have been functionally characterized.	1.1109e-12
NC_015949.1\|WP_014043403.1\|2605560_2607774_-\|ATP-dependent-RecD-like-DNA-helicase	gnl\|CDD\|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	0
NC_015949.1\|WP_013433704.1\|2608952_2609165_-\|DUF1659-domain-containing-protein	gnl\|CDD\|377933	pfam07872, DUF1659, Protein of unknown function (DUF1659). This family consists of hypothetical bacterial proteins of unknown function.	1.46615e-10
NC_015949.1\|WP_013433714.1\|2618665_2620588_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.4638e-106
NC_015949.1\|WP_013433715.1\|2620652_2621633_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|187821	cd09690, Cas7_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csh2 family.	4.14483e-87
NC_015949.1\|WP_013433711.1\|2616814_2617318_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.51721e-58
NC_015949.1\|WP_014043405.1\|2609850_2610861_+\|stage-V-sporulation-protein-AD	gnl\|CDD\|236230	PRK08304, PRK08304, stage V sporulation protein AD; Validated.	0
NC_015949.1\|WP_014043409.1\|2621655_2622387_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	4.81053e-31
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	gnl\|CDD\|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	1.65162e-10

>NC_015949.1|WP_014043407.1|2611321_2611729_-|hypothetical-protein
MVILNKLFLIFNHQLSEEQEKEAREVLKVEEIVSLPPQLQDFWSSIPPDVELTEEMFEDITAFLLQNRGEKENFCLVQGDFGATVYIVSWCFKNGFVPIYATTKRVSKEIVRPDGSVELHKVFKHERFRKYILCR
>NC_015949.1|WP_049783163.1|2610945_2611263_+|stage-V-sporulation-protein-AE
MCVVGQILIDKTKLTSARVLVLFVTLGAVLQGLGIYQKLVEFAGAGATVPLPGFGYSLAKGAIEEVNRIGLVGAFTGGVSKTAGGISAAVFFGYVISLIFNPRSK
>NC_015949.1|WP_014043405.1|2609850_2610861_+|stage-V-sporulation-protein-AD
MKLGRSTYRFESNVAISDCFTVVGKKEGQGPLSIYFDMVIEDEYAGQKSWKLAEGKLLNIAITKLVQRSGENPDNIDLILSGDLLNQLSSSHFAARDLDIPFVGIYGACSTFALSVGLASIFVDSSFAKNVIAATSSHFCSAEKQFRYPLELGTQRPPTSQLTVTGAAAFLIRQEDSLQSPKVTHFTVGRILDFGIKDPNNMGAAMAPAAFDTIMRHFSDTKRCFEYYDMIITGDLGYVGRKLLEELFKKEGISFCSELFDCGILMFDPKTQNTGAGASGCAASACVFGGYLYKLLRERTFERILIVPTGALMSQSTVQLGESIPVIAHALAIEMV
>NC_015949.1|WP_014043404.1|2609373_2609832_+|stage-V-sporulation-protein-AC
MNIKEKKVSEYQALVKANEPKTNSFKNCILAFLIGGAICDVGQAFLNLYSSFFPKDEAQVLTSITMIFLGAFLTGLGVYDKIGAFAGAGSIVPITGFANSIVSPAIEYKKEGFVFGVGSKMFLIAGPVLVYGISTSILVGLLYYLVKVFPGI
>NC_015949.1|WP_013433704.1|2608952_2609165_-|DUF1659-domain-containing-protein
MAAKPLVGSLQLKLENGTTSTGRIRLKTLSFDIKPDAQDMDVYQVGQAIASLQSKPLYTIIRSNNFELLY
>NC_015949.1|WP_013433703.1|2608682_2608895_-|DUF2922-domain-containing-protein
MLTLVLTFKLQNGKTFRLSIPDPKPNLTAAEVDSVMNLIVQKNIFATSSPIVEKVSARIVDREVNTLIGQ
>NC_015949.1|WP_013404408.1|2608420_2608570_-|YvrJ-family-protein
MQDIIANIANIGFPIVLCIYLLTRFESKIDKLSDSIDKLSEKILQMKNN
>NC_015949.1|WP_013433702.1|2607823_2608336_-|hypothetical-protein
MNSIPKDIIYFVPHYTENGDSVLILFLSGEKKIVPMSIRSFSKKLYSLYAIDCQAIKKLISQRIGQKNLLPIVLPDATFIPVKTRKAVVKTDPIFGYVNMSQIFRIDDKIDHFEMLLRCGAVLRCLGSAKYFKKRITLASVITDYLQGIWSQGALKIKEECELENVFGLE
>NC_015949.1|WP_014043403.1|2605560_2607774_-|ATP-dependent-RecD-like-DNA-helicase
MQQNIQGMVSDIIYRNLENSYTVFEIICDDEVFTAVGIVPDIAIGEKVSVYGEFYVHPVYGQQLKVSYLEKLLPQTKDEIYLYLSSGVIKGIGQKTAKKIVDTFGEDTARVLQEEPEKLLQIRGMTPEKVERIRNMFAFQKFLKDIMSIFSQYGLSQNHAMRLFKLYGFSALSLLQENPYFLLDVFPELDFKKVDRLALDMGVMPDDRRRISAKILNLLTLAANNEGHTCLPENRLKQLCSKTLDLPVEKIEEALEALEVERRVVKDEVDSQEMVFLYGYYECERYIADKILSMLKEYDDIADIDEKISMFEERNGIVFSPNQKKAIKMALTQGVSIITGGPGTGKTTIIKCIIQIFESEGKKVFLCAPTGRAAKRMQAACERESKTIHRLLEMTVLDTHVIFQKGPSNPLKCDVIIVDEMSMVDSFLMNYLLAATKPSTRIVLVGDKDQLPSVGAGNVLKDLIKSEIVPCTTLTEVYRQSENSFIVLNAHRINRGEFPHLQKESDFYFIQKNSQEEILKTVVELVTKKLPNYLSCDPMTDIQVLCPSKKGIVGMYNLNRVLQQHLNPPHPSKKEYVYKENLFRVGDKVMQIKNNYSLEYEIVQGEEKGRGWAGIFNGDIGVVKDIDRAQGALEILFDDEKLVYYDFSLLDDLELAYAMTVHKSQGSEFRCIVMPVVETYPILMTRNLLYTAVTRAKELVVLVGKKSALEYMIANQKEAMRYSGLYDFLKKKIDVVT
>NC_015949.1|WP_014043402.1|2604785_2605478_+|hypothetical-protein
MKKRIIFYFCVLITITIVVVYIYNVLHKHPTSRDYIYMAGMRSASLIEINTEEIYGLLPQNLNNFENWFTNDKLEKLYIYYNNLSYTLDTFLFLNSSLNSNYLHFCRKIRPLYDNIFYLILYSSHDSKDLYMIRVNGIPIQVKSFYQKYAIEKQKINKYDEEYYQYLRQLLVRITDQVFEVKYYGDTKTYPIFLKKELPKILDLEKEFNKKTEEYLKKIGLYDKYAKQQE
>NC_015949.1|WP_013433710.1|2616286_2616667_+|hypothetical-protein
MSYLPKSPKEVYEQILLEYQAYSEFKKRIEGKCYLPHDPENVLYLYCNSTFNEEYEEMLKSKQIENYVEPQTEEEWEYYAEEDEYCKEEFENDFEFFDADYEMSSEMDDIVDDPDFWDSFDYEWGD
>NC_015949.1|WP_013433711.1|2616814_2617318_+|CRISPR-associated-protein-Cas4
MERFLDIKGHIVQAYVVCKRQAWLLSRNISPVQDNPFLEIGKLISQQFYKHDKKEVYFDGVVLDLIRKEDEVLVVGEIKKSSKKVAAAILQLKFYLYKLLKHNIKARGKLLIPEEKKTYDVELTFEDIETIESLLSEITEVLSSFLPPLPQKIKACAKCSYKEFCWA
>NC_015949.1|WP_013433712.1|2617314_2618310_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKRPIYIFSDGVLKRKNNTLYFESEGVQKFIPVENTSEIYIFGEVELNKRFLEFLTQSEIILHFFNRYGYYVGSFYPREYLNSGYMILKQAEHYLDTQKRLSLARTFVEGSYKNMRQVLKYYQSRGIDELERYIQQMENLFGSISNINDINTLMAIEGNIRQTYYSAFDLIIDKDDFKFEKRSKRPPKNALNALISFGNSMMYTIVLSEIYRTHLDPRIGYLHTTNFRRFTLNLDVAEIFKPIIVDRLIFSIISKNMLKPEHFEQNLEGIVITDSAKKLFIDELEQRLSTTISVKNIGNYVSYRQLIRIELYKIEKHLMGEKEYQPYVSQW
>NC_015949.1|WP_014043408.1|2618325_2618589_+|CRISPR-associated-endonuclease-Cas2
MYTILVYDVNEKRVAKALKVCRKYLNWVQNSVFEGEISEAKLKKLKFELSQKLNLHEDSVIIYNFQSRLYSQREILGVEKNNLDRFI
>NC_015949.1|WP_013433714.1|2618665_2620588_+|TIGR02556-family-CRISPR-associated-protein
MIEAVAEIGKFLIEKKSKASGKSCADDQSNNLSSFLTPVESEKVILICLKQKQTEFEYCGLDLQNPLVSRAQLYLFSQGAKGGGTNYSPVCILTKPKTPKTMTEEQVKQATKEQVEKVFKQKVENWFLNKALPLAKKFSKQGDISKEDAYFIQCISQAVSENREKIIEDISELLFEVEFEKQKSSALLTFSIDGKYIGEYEIFKSFLLELIKEKAERSSSQDKTCSICKQKRENVSGTVNVFKFYTIDKPGFIRGGFSSENAWKNFPVCSSCQIHLSEGRKYLEKELQFKFYNFKYLLIPQLIFSTSSAYSEVLDILQNTKKEISLGEKALERITDDENEILDVISTFNDSISVTFLFMVPQMGAERIVLMIEDVLPSHLKNIFDAKRHTERKYRTVFNNPDINFTFQQIKHFFSKSNRLKKKSDLDSYFLEITESIFKKKPIDFQFLAAHFCRRLQDSIANKDFFDFYTSCSYAIEVLEFLNKLEILKLKGDEFGMSYETPFDEILNEFPVASANPAVKGIILVGALCDILMRIQSTALSKTPGKMPPFAKNLKGLRLKQSDIVSLLPKIENKLMEYSSFGKANRLIASSASELLLKSPVDWKLSADEVSFYFACGMNLGQKIREHAKKLTGDTDEQEA
>NC_015949.1|WP_013433715.1|2620652_2621633_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MENAKEIIKNRSEVLFLYDVTDANPNGDPLDENKPRIDPETDTCIVTDVRLKRTCRDYWAEYKNLPVFILREISEDGKLMTKSDKFSKYNLSKEKLKDYIDIRLFGGTTTLKSKDEKKKSKSDEDLSEETGAITFTGPVQFKFGRSLHKVEYMLVKGTTVMPSGEGKDQGTFTECYILPYALIAFYGVVNENAALCQELPVTEEDIQLLLEALWCGTKNLISRSKFGQMPRLLVRVEYNQSGFYIGELDKLVKLISQKSDTAIRSPEDFQLDITRLVEKLTKHQDKIQKVQVSVDHSISFVCEGKFVHLKDALSFLGDRVKLLQFE
>NC_015949.1|WP_014043409.1|2621655_2622387_+|type-I-B-CRISPR-associated-protein-Cas5
MKVAVFDIKADFGFFGKFYSTSSPITYPFPPFPTIQGMVGAILGLDKKEYLDILEYGKFRAGIRILNPVKKIRMGINHIDTKEGRWQPIKTKNRQPRTQMRFELLKDPRFRIYATLATESLFSRLVEFLQQHRSYFTLSMGLSEFLADFEFVGVFEAVEKGMPNDYVSLCTPIPLSYLDSKAEIPLRIEAGKSYFKERMPLYMLSTREVVKYEDVIFEPTGKELLARPSSYVEVQNGENILLF
>NC_015949.1|WP_014043410.1|2622361_2624830_+|CRISPR-associated-helicase/endonuclease-Cas3
MEKTSFCFDSKNLSGLFSHPGKDGSIQGAKPLEVHLTNTSILANCFASEKNIALCSTKFLSQIAKITALLHDIGKATSFFQKYLFDKKKTKSRHTRHSLISAICVWGTLNRLIEEKKIQEDKTFEGFTAILAFFATLKHHGDLEATSDMLLLSEDDIELCYEQIENIDKEKFNTLILNISCLCPEIGFLTIDSLREFVDHAKVSIKLFKRAFRKLFDTEMKFFFMLNLLYSILLDADKTEAIFGTLVDIPELNLSYIDVDSFRRRIFKPENFENSIKALRDSAFEEATNCEIDENRRIYTLCLPTGLGKTIISFAFALKLRELAQKRFSSKFRIIYSLPFLSIIEQNYDVISKILSFCGLDITSDILLKHHHLSDIVYKTKDGLQNNQEEIFDTDIAKLLIEGWNSNIIVTTFVQFLESIMTNKNSNMRKFHRIANSIIILDEVQAINSEYWFLCKNLFEKMCSSLNCFIILSTATMPFIVDKKTAVEIVKPEKYFDKLCRTVLHFDNNFSKIGLEEFVAKFEFEKEKTYLFVMNTVSSAKKLYELINQRFPDMQDEITILTTHIIPKERLRRIEQIKNKKYKIVVSTQLVEAGVDVDFDHVVRDIAPLDSIIQAAGRANREGKKGKSKVTVIELVSDRGRLFATEVYDSLLIDATKKILSQFQKVDESKFAELIFEYYKELARRGVIETSSDDKGTSQKFLEAIYRLLYTSSDSETDAIGSFKLIEDEPYKVDVFVEADEEAKIIWQRFEEICEIKDFFERKKKFLEIRKSFYDYIISVPKTTNLPVNFENLIFRIPHSQLSDFYDPITGFKTKGESYLSF
>NC_015949.1|WP_041725840.1|2625756_2627148_-|ATP-binding-protein
MKKFINRKHELDFLEKQYQEQKSSLVVIYGRRRIGKTALIKKFIEDKPTIYFLASEEVESQNIEYFKRTVSGFLKNPLIEKLSGISWDDIFDILVKTKSNKKIVIVLDEFQNLCKTNPAFASILQRIWDEKLKSGNFMLILCGSLISMMQEYALSYSSPLYGRRTGQIKLKQFSFKEAKEFFPDASDDEFIWIYSVVGGVPKYLEMFKYEGDIYKAIEENILSRQSFLYEEPLFLLEKEVHEIGSYFSIIKSIALGNHKLSQIAQSLSVPQTKLTKYLNTLIELDIIRREVPITEEYPEKSKRGLYFINDNFINFWFKFVYPYREQLELDNIEYVIENIRSKIVASHISYVYEEVCKQILSDLIRSEKIDVQIDKIGKWWDGKSEIDIVGIGRSMRHVVFGECKYSQNMIDIDVFFDLKKKAENVKVFPDQKEFYILFSKAGFSERLLEYAAEEKNIVLIKFP
>NC_015949.1|WP_014043413.1|2628542_2629748_-|putative-CRISPR-associated-protein
MPKYSNIVMTGGISAFNSSNVFYQYFAEFIENKSSYAGQNLEKVLEEICKEKGLTDKELERLVKERPNQISAEFSMLKGLKEKDLLDDIINISVIHSDTPDGIMAALINKKVIELVFKDSTVSLEKVEDVDISNEVKLQRSLGYFMKIVANELLKGTKETTFFAPIGGYKYMAYLGYVAGALFGYSSGYMYEKGQKLLTIPPIPIEINFDLITKNKNFIRNLLTEGQLNYQSLSPDEKEIVDTMPYFFEKVEIDGQEIVSANAFAEFIFGDYISTAVKVSPEVSDLISKNEQYRNFILNQLMGLIKKANSFFKDYRNYQGLRGELMHNENWGIDRPYLYKGSSNGNKLVFRCAYDFDYKSRILYIYKIWLNHDKYEREAEAIKNGKITIDMDKNKMFELEY

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Crispr_ID: NC_015949_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_10

2625215-2625641

TypeI

Consensus_repeat	Method
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	CRISPRCasFinder
GTTTGTAGCCTNCCCTTTGGGGATTGAAA	CRT

6 spacers

cas3,cas5,cas7,cas8b1,cas2,cas1,cas4,csx20,csm6,csm2gr11,csm3gr7,csx10gr5,cas10

The CRISPR arrays of NC_015949_10

>merge|NC_015949|10|2625215-2625641|CRISPRCasFinder,CRT
GTTTGTAGCCTCCCCTTTGGGGATTGAAATTTTCCCAGTTTGTGCACAATCTATTCCATATAAAATCTGTTTGTAGCCTCCCCTTTGGGGATTGAAATCTGACATTTAACTTATCTATCGCCCAAAGCAATTGGTTTGTAGCCTCCCCTTTGGGGATTGAAATAAACAATCATATATAACTCTTTTAAATTGTATTTTGTTTGTAGCCTTCCCTTTGGGGATTGAAACGCTTGTGGATAAAATAAATCTGGAGCCCATTTTGGGAGTTTGTAGCCTTCCCTTTGGGGATTGAAACAACAATTTTCAAGTTTTTCAAACTGCATTTCATCAAGTTTGTAGCCTTCCCTTTGGGGATTGAAACACCTATTTTTCTGAGGAAAGCCATAGCAGCCTCCTCGTTTGTAGCCTGCCCTTTGGGGATTGAGGT

>NC_015949|10|10|2625215-2625641|CRISPRCasFinder
GTTTGTAGCCTCCCCTTTGGGGATTGAAAT	TTTCCCAGTTTGTGCACAATCTATTCCATATAAAATCT
GTTTGTAGCCTCCCCTTTGGGGATTGAAAT	CTGACATTTAACTTATCTATCGCCCAAAGCAATTG
GTTTGTAGCCTCCCCTTTGGGGATTGAAAT	AAACAATCATATATAACTCTTTTAAATTGTATTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	GCTTGTGGATAAAATAAATCTGGAGCCCATTTTGGGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	AACAATTTTCAAGTTTTTCAAACTGCATTTCATCAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAAC	ACCTATTTTTCTGAGGAAAGCCATAGCAGCCTCCTC
GTTTGTAGCCTGCCCTTTGGGGATTGAGGT

>NC_015949|10|9|2625215-2625640|CRT
GTTTGTAGCCTCCCCTTTGGGGATTGAAA	TTTTCCCAGTTTGTGCACAATCTATTCCATATAAAATCT
GTTTGTAGCCTCCCCTTTGGGGATTGAAA	TCTGACATTTAACTTATCTATCGCCCAAAGCAATTG
GTTTGTAGCCTCCCCTTTGGGGATTGAAA	TAAACAATCATATATAACTCTTTTAAATTGTATTTT
GTTTGTAGCCTTCCCTTTGGGGATTGAAA	CGCTTGTGGATAAAATAAATCTGGAGCCCATTTTGGGA
GTTTGTAGCCTTCCCTTTGGGGATTGAAA	CAACAATTTTCAAGTTTTTCAAACTGCATTTCATCAA
GTTTGTAGCCTTCCCTTTGGGGATTGAAA	CACCTATTTTTCTGAGGAAAGCCATAGCAGCCTCCTC
GTTTGTAGCCTGCCCTTTGGGGATTGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_049783163.1\|2610945_2611263_+\|stage-V-sporulation-protein-AE	unknown	unknown	gnl\|CDD\|131886
NC_015949.1\|WP_041725840.1\|2625756_2627148_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224586
NC_015949.1\|WP_014043416.1\|2631013_2631904_-\|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187814
NC_015949.1\|WP_014043419.1\|2633267_2634407_-\|hypothetical-protein	csx10gr5	cd09700_csx10gr5_CAS-III-D	gnl\|CDD\|187831
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl\|CDD\|187873
NC_015949.1\|WP_013433712.1\|2617314_2618310_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NC_015949.1\|WP_014043407.1\|2611321_2611729_-\|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_015949.1\|WP_014043408.1\|2618325_2618589_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015949.1\|WP_014043410.1\|2622361_2624830_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_015949.1\|WP_013433710.1\|2616286_2616667_+\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043421.1\|2634965_2636972_-\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|274208
NC_015949.1\|WP_014043417.1\|2631945_2632728_-\|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274211
NC_015949.1\|WP_013433714.1\|2618665_2620588_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_015949.1\|WP_014043420.1\|2634403_2634946_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NC_015949.1\|WP_013433715.1\|2620652_2621633_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|187821
NC_015949.1\|WP_014043414.1\|2629765_2630131_-\|hypothetical-protein	csm2gr11	mkCas0101_csm2gr11_CAS-III-D	unknown
NC_015949.1\|WP_013433711.1\|2616814_2617318_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_015949.1\|WP_014043418.1\|2632760_2633255_-\|hypothetical-protein	csm2gr11	mkCas0079_csm2gr11_CAS-III-D	unknown
NC_015949.1\|WP_014043415.1\|2630148_2631030_-\|hypothetical-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
NC_015949.1\|WP_014043409.1\|2621655_2622387_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015949.1\|WP_014043416.1\|2631013_2631904_-\|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	1e-31	104.8	0.3
NC_015949.1\|WP_014043419.1\|2633267_2634407_-\|hypothetical-protein	csx10gr5	cd09700_csx10gr5_CAS-III-D	2.2e-15	51.6	0.0
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	1.8e-20	67.7	0.2
NC_015949.1\|WP_013433712.1\|2617314_2618310_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	1.1e-137	453.1	13.8
NC_015949.1\|WP_014043407.1\|2611321_2611729_-\|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	2.6e-59	193.8	0.1
NC_015949.1\|WP_014043408.1\|2618325_2618589_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	5e-29	95.1	1.3
NC_015949.1\|WP_014043410.1\|2622361_2624830_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	3.6e-52	172.3	18.6
NC_015949.1\|WP_014043421.1\|2634965_2636972_-\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	1.8e-54	180.0	0.1
NC_015949.1\|WP_014043417.1\|2631945_2632728_-\|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	1.7e-45	149.8	0.0
NC_015949.1\|WP_013433714.1\|2618665_2620588_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	1.5e-109	362.0	27.3
NC_015949.1\|WP_014043420.1\|2634403_2634946_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	1.3e-19	66.1	0.0
NC_015949.1\|WP_013433715.1\|2620652_2621633_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	2e-85	281.3	0.1
NC_015949.1\|WP_014043414.1\|2629765_2630131_-\|hypothetical-protein	csm2gr11	mkCas0101_csm2gr11_CAS-III-D	1.6e-58	190.7	4.9
NC_015949.1\|WP_013433711.1\|2616814_2617318_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	4.5e-46	151.7	0.5
NC_015949.1\|WP_014043418.1\|2632760_2633255_-\|hypothetical-protein	csm2gr11	mkCas0079_csm2gr11_CAS-III-D	6.9e-52	169.7	8.9
NC_015949.1\|WP_014043415.1\|2630148_2631030_-\|hypothetical-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	1.1e-23	78.8	2.3
NC_015949.1\|WP_014043409.1\|2621655_2622387_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	2.1e-34	113.9	0.0

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_049783163.1\|2610945_2611263_+\|stage-V-sporulation-protein-AE	gnl\|CDD\|131886	TIGR02839, stage_V_sporulation_protein_AE, stage V sporulation protein AE. This model describes stage V sporulation protein AE, a paralog of stage V sporulation protein AC. Both are proteins found to present in a species if and only if that species is one of the Firmicutes capable of endospore formation, as of the time of the publication of the genome of Carboxydothermus hydrogenoformans. Mutants in spoVAE have a stage V sproulation defect. [Cellular processes, Sporulation and germination].	2.99454e-42
NC_015949.1\|WP_041725840.1\|2625756_2627148_-\|ATP-binding-protein	gnl\|CDD\|224586	COG1672, COG1672, Predicted ATPase (AAA+ superfamily) [General function prediction only].	2.46699e-30
NC_015949.1\|WP_014043417.1\|2631945_2632728_-\|CRISPR-associated-RAMP-protein	gnl\|CDD\|274211	TIGR02581, putative_CRISPR-associated_protein, CRISPR-associated RAMP protein, SSO1426 family. Members of this CRISPR-associated (cas) gene family are found in the RAMP-2 subtype of CRISPR/cas locus and designated TM1809 family.	5.94912e-42
NC_015949.1\|WP_014043419.1\|2633267_2634407_-\|hypothetical-protein	gnl\|CDD\|187831	cd09700, Csx10, CRISPR/Cas system-associated RAMP superfamily protein Csx10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Duplicated RAMP domains.	1.05984e-13
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	gnl\|CDD\|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	1.65162e-10
NC_015949.1\|WP_013433712.1\|2617314_2618310_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	5.1355e-168
NC_015949.1\|WP_014043410.1\|2622361_2624830_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	5.6921e-52
NC_015949.1\|WP_014043408.1\|2618325_2618589_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.87467e-29
NC_015949.1\|WP_014043416.1\|2631013_2631904_-\|hypothetical-protein	gnl\|CDD\|187814	cd09683, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	5.46159e-25
NC_015949.1\|WP_014043421.1\|2634965_2636972_-\|hypothetical-protein	gnl\|CDD\|274208	TIGR02577, thermophile-specific_DNA_repair_system, CRISPR-associated protein Cas10/Cmr2, subtype III-B. This model represent a Crm2 family of the CRISPR-associated RAMP module, a set of six genes recurring found together in prokaryotic genomes. This gene cluster is found only in species with CRISPR repeats, usually near the repeats themselves. Because most of the six (but not this family) contain RAMP domains, and because its appearance in a genome appears to depend on other CRISPR-associated Cas genes, the set is designated the CRISPR RAMP module. This protein, typified by TM1794 from Thermotoga maritima, is designated Crm2, for CRISPR RAMP Module protein 2.	4.23072e-08
NC_015949.1\|WP_013433714.1\|2618665_2620588_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.4638e-106
NC_015949.1\|WP_014043420.1\|2634403_2634946_-\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	7.31705e-16
NC_015949.1\|WP_013433715.1\|2620652_2621633_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|187821	cd09690, Cas7_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csh2 family.	4.14483e-87
NC_015949.1\|WP_013433711.1\|2616814_2617318_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.51721e-58
NC_015949.1\|WP_014043415.1\|2630148_2631030_-\|hypothetical-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	8.03721e-15
NC_015949.1\|WP_014043409.1\|2621655_2622387_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	4.81053e-31

>NC_015949.1|WP_014043410.1|2622361_2624830_+|CRISPR-associated-helicase/endonuclease-Cas3
MEKTSFCFDSKNLSGLFSHPGKDGSIQGAKPLEVHLTNTSILANCFASEKNIALCSTKFLSQIAKITALLHDIGKATSFFQKYLFDKKKTKSRHTRHSLISAICVWGTLNRLIEEKKIQEDKTFEGFTAILAFFATLKHHGDLEATSDMLLLSEDDIELCYEQIENIDKEKFNTLILNISCLCPEIGFLTIDSLREFVDHAKVSIKLFKRAFRKLFDTEMKFFFMLNLLYSILLDADKTEAIFGTLVDIPELNLSYIDVDSFRRRIFKPENFENSIKALRDSAFEEATNCEIDENRRIYTLCLPTGLGKTIISFAFALKLRELAQKRFSSKFRIIYSLPFLSIIEQNYDVISKILSFCGLDITSDILLKHHHLSDIVYKTKDGLQNNQEEIFDTDIAKLLIEGWNSNIIVTTFVQFLESIMTNKNSNMRKFHRIANSIIILDEVQAINSEYWFLCKNLFEKMCSSLNCFIILSTATMPFIVDKKTAVEIVKPEKYFDKLCRTVLHFDNNFSKIGLEEFVAKFEFEKEKTYLFVMNTVSSAKKLYELINQRFPDMQDEITILTTHIIPKERLRRIEQIKNKKYKIVVSTQLVEAGVDVDFDHVVRDIAPLDSIIQAAGRANREGKKGKSKVTVIELVSDRGRLFATEVYDSLLIDATKKILSQFQKVDESKFAELIFEYYKELARRGVIETSSDDKGTSQKFLEAIYRLLYTSSDSETDAIGSFKLIEDEPYKVDVFVEADEEAKIIWQRFEEICEIKDFFERKKKFLEIRKSFYDYIISVPKTTNLPVNFENLIFRIPHSQLSDFYDPITGFKTKGESYLSF
>NC_015949.1|WP_014043409.1|2621655_2622387_+|type-I-B-CRISPR-associated-protein-Cas5
MKVAVFDIKADFGFFGKFYSTSSPITYPFPPFPTIQGMVGAILGLDKKEYLDILEYGKFRAGIRILNPVKKIRMGINHIDTKEGRWQPIKTKNRQPRTQMRFELLKDPRFRIYATLATESLFSRLVEFLQQHRSYFTLSMGLSEFLADFEFVGVFEAVEKGMPNDYVSLCTPIPLSYLDSKAEIPLRIEAGKSYFKERMPLYMLSTREVVKYEDVIFEPTGKELLARPSSYVEVQNGENILLF
>NC_015949.1|WP_013433715.1|2620652_2621633_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MENAKEIIKNRSEVLFLYDVTDANPNGDPLDENKPRIDPETDTCIVTDVRLKRTCRDYWAEYKNLPVFILREISEDGKLMTKSDKFSKYNLSKEKLKDYIDIRLFGGTTTLKSKDEKKKSKSDEDLSEETGAITFTGPVQFKFGRSLHKVEYMLVKGTTVMPSGEGKDQGTFTECYILPYALIAFYGVVNENAALCQELPVTEEDIQLLLEALWCGTKNLISRSKFGQMPRLLVRVEYNQSGFYIGELDKLVKLISQKSDTAIRSPEDFQLDITRLVEKLTKHQDKIQKVQVSVDHSISFVCEGKFVHLKDALSFLGDRVKLLQFE
>NC_015949.1|WP_013433714.1|2618665_2620588_+|TIGR02556-family-CRISPR-associated-protein
MIEAVAEIGKFLIEKKSKASGKSCADDQSNNLSSFLTPVESEKVILICLKQKQTEFEYCGLDLQNPLVSRAQLYLFSQGAKGGGTNYSPVCILTKPKTPKTMTEEQVKQATKEQVEKVFKQKVENWFLNKALPLAKKFSKQGDISKEDAYFIQCISQAVSENREKIIEDISELLFEVEFEKQKSSALLTFSIDGKYIGEYEIFKSFLLELIKEKAERSSSQDKTCSICKQKRENVSGTVNVFKFYTIDKPGFIRGGFSSENAWKNFPVCSSCQIHLSEGRKYLEKELQFKFYNFKYLLIPQLIFSTSSAYSEVLDILQNTKKEISLGEKALERITDDENEILDVISTFNDSISVTFLFMVPQMGAERIVLMIEDVLPSHLKNIFDAKRHTERKYRTVFNNPDINFTFQQIKHFFSKSNRLKKKSDLDSYFLEITESIFKKKPIDFQFLAAHFCRRLQDSIANKDFFDFYTSCSYAIEVLEFLNKLEILKLKGDEFGMSYETPFDEILNEFPVASANPAVKGIILVGALCDILMRIQSTALSKTPGKMPPFAKNLKGLRLKQSDIVSLLPKIENKLMEYSSFGKANRLIASSASELLLKSPVDWKLSADEVSFYFACGMNLGQKIREHAKKLTGDTDEQEA
>NC_015949.1|WP_014043408.1|2618325_2618589_+|CRISPR-associated-endonuclease-Cas2
MYTILVYDVNEKRVAKALKVCRKYLNWVQNSVFEGEISEAKLKKLKFELSQKLNLHEDSVIIYNFQSRLYSQREILGVEKNNLDRFI
>NC_015949.1|WP_013433712.1|2617314_2618310_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKRPIYIFSDGVLKRKNNTLYFESEGVQKFIPVENTSEIYIFGEVELNKRFLEFLTQSEIILHFFNRYGYYVGSFYPREYLNSGYMILKQAEHYLDTQKRLSLARTFVEGSYKNMRQVLKYYQSRGIDELERYIQQMENLFGSISNINDINTLMAIEGNIRQTYYSAFDLIIDKDDFKFEKRSKRPPKNALNALISFGNSMMYTIVLSEIYRTHLDPRIGYLHTTNFRRFTLNLDVAEIFKPIIVDRLIFSIISKNMLKPEHFEQNLEGIVITDSAKKLFIDELEQRLSTTISVKNIGNYVSYRQLIRIELYKIEKHLMGEKEYQPYVSQW
>NC_015949.1|WP_013433711.1|2616814_2617318_+|CRISPR-associated-protein-Cas4
MERFLDIKGHIVQAYVVCKRQAWLLSRNISPVQDNPFLEIGKLISQQFYKHDKKEVYFDGVVLDLIRKEDEVLVVGEIKKSSKKVAAAILQLKFYLYKLLKHNIKARGKLLIPEEKKTYDVELTFEDIETIESLLSEITEVLSSFLPPLPQKIKACAKCSYKEFCWA
>NC_015949.1|WP_013433710.1|2616286_2616667_+|hypothetical-protein
MSYLPKSPKEVYEQILLEYQAYSEFKKRIEGKCYLPHDPENVLYLYCNSTFNEEYEEMLKSKQIENYVEPQTEEEWEYYAEEDEYCKEEFENDFEFFDADYEMSSEMDDIVDDPDFWDSFDYEWGD
>NC_015949.1|WP_014043407.1|2611321_2611729_-|hypothetical-protein
MVILNKLFLIFNHQLSEEQEKEAREVLKVEEIVSLPPQLQDFWSSIPPDVELTEEMFEDITAFLLQNRGEKENFCLVQGDFGATVYIVSWCFKNGFVPIYATTKRVSKEIVRPDGSVELHKVFKHERFRKYILCR
>NC_015949.1|WP_049783163.1|2610945_2611263_+|stage-V-sporulation-protein-AE
MCVVGQILIDKTKLTSARVLVLFVTLGAVLQGLGIYQKLVEFAGAGATVPLPGFGYSLAKGAIEEVNRIGLVGAFTGGVSKTAGGISAAVFFGYVISLIFNPRSK
>NC_015949.1|WP_041725840.1|2625756_2627148_-|ATP-binding-protein
MKKFINRKHELDFLEKQYQEQKSSLVVIYGRRRIGKTALIKKFIEDKPTIYFLASEEVESQNIEYFKRTVSGFLKNPLIEKLSGISWDDIFDILVKTKSNKKIVIVLDEFQNLCKTNPAFASILQRIWDEKLKSGNFMLILCGSLISMMQEYALSYSSPLYGRRTGQIKLKQFSFKEAKEFFPDASDDEFIWIYSVVGGVPKYLEMFKYEGDIYKAIEENILSRQSFLYEEPLFLLEKEVHEIGSYFSIIKSIALGNHKLSQIAQSLSVPQTKLTKYLNTLIELDIIRREVPITEEYPEKSKRGLYFINDNFINFWFKFVYPYREQLELDNIEYVIENIRSKIVASHISYVYEEVCKQILSDLIRSEKIDVQIDKIGKWWDGKSEIDIVGIGRSMRHVVFGECKYSQNMIDIDVFFDLKKKAENVKVFPDQKEFYILFSKAGFSERLLEYAAEEKNIVLIKFP
>NC_015949.1|WP_014043413.1|2628542_2629748_-|putative-CRISPR-associated-protein
MPKYSNIVMTGGISAFNSSNVFYQYFAEFIENKSSYAGQNLEKVLEEICKEKGLTDKELERLVKERPNQISAEFSMLKGLKEKDLLDDIINISVIHSDTPDGIMAALINKKVIELVFKDSTVSLEKVEDVDISNEVKLQRSLGYFMKIVANELLKGTKETTFFAPIGGYKYMAYLGYVAGALFGYSSGYMYEKGQKLLTIPPIPIEINFDLITKNKNFIRNLLTEGQLNYQSLSPDEKEIVDTMPYFFEKVEIDGQEIVSANAFAEFIFGDYISTAVKVSPEVSDLISKNEQYRNFILNQLMGLIKKANSFFKDYRNYQGLRGELMHNENWGIDRPYLYKGSSNGNKLVFRCAYDFDYKSRILYIYKIWLNHDKYEREAEAIKNGKITIDMDKNKMFELEY
>NC_015949.1|WP_014043414.1|2629765_2630131_-|hypothetical-protein
MKDKKELLEIAKKIESELSSSNSSFISDIVSFIIASKIEKNSKEEQLKRFLEFLWFCTKNPNVLGGGNTKKNGFKKFIEDYLKLKKENGNFILGNGDFSCLDIDDLFFVFAWAKRIVKSSR
>NC_015949.1|WP_014043415.1|2630148_2631030_-|hypothetical-protein
MSKSYSFIAFLETKENYNNSYTTKLSAELLKYEKLRLQIETLSYLHIWSGMYSEKNGLIYRTFIKSNGKYIIPGSSLKGCVRTVAEMVSYSCMGVATNEQTKVKIPVKKWHSDKRKRCIVCDMFGAPGNKSKLIFHDFAVVSVEDYSKITELICIPPSFEPHPPECDDYKDENGNFKGYKIYNHGEFKSASPDNGIWIEAVKPGVRFEGEIWLRADLKQEQKELLCFSLGLSGFDLKIGYGKNHYLGSIRIGAVNGSSELIDLAKKYEAKADDKVKNNIMKIKEIWQFKNEKV
>NC_015949.1|WP_014043416.1|2631013_2631904_-|hypothetical-protein
MFKKLLNQAIVNFELVTQSPLYIKQNTSLLDPTAFDGTYISCYLDDQRIPIIPGTSMKGVFRSFFEKMLGEEACDILDTRQDSNKCLKTIKEYEEKLKSSNKKDKTNNFDEELEKLKDFSRGKLNYYLSCPACKVFGSQRLKSRMLFDDAKAKEGFKISSRSSTPIDRISGAAKEKGLNTFEYVDWGVFEAKITLVNFFNWQLKLLLEIFERIDEGILMFGGYSSKGFGRMKVENVTIKVRYYGEMKGKAKDGYSQNALFAERVFNNKEVKEKLQSIDFLDKNQWAKVELKDEQIL
>NC_015949.1|WP_014043417.1|2631945_2632728_-|CRISPR-associated-RAMP-protein
MLLFDKFENRYIIKGIITNLNPIHIGAGGASFNPLEVDNRIVRYASTNEPYIPGSSLKGVLRSFFEQIYPKEHCWATINPCSKKKEKEIEDKRKKYSENPEGYAKEVYSLLCDICKVFGSQETASKIYISDLKVREENGKKLYKLGVRDGVGIDRDTGTAANRMKYDFEVIEPGAKFDLYMVFENLENEYVKSFLIPIVEVLKSGELKIGGKTSRGLGRIKLLEDFKIYKITKDNIKNYLEKGLNEIEPLSWADFKKQFE
>NC_015949.1|WP_014043418.1|2632760_2633255_-|hypothetical-protein
MKEEARKEIIKMLVQWADKIGENKNFWKQNRELGKTNIRTTATAILQASCYNEVKLFLEYKGSRKNTGWDKLFNNNTTFANYIISKIEDLRKKVDEKYKEDPTFDKEKEVIELAARFLGYIYWKIYGLVNQKENEERQPQNSNQSPQMKGTNYQGRSGSRQSRS
>NC_015949.1|WP_014043419.1|2633267_2634407_-|hypothetical-protein
MKVYLNFKSPVLVGGRKSATNFIESINYIPGSVVRAALAKFVVLNCKAQRDVYGESSEKRFWVEFKNKEECQRCEFTNLCKNFNEIKISFFYPKGAKPNPLCDMICKNNEDHGFYSELLYGSEDKEAKCLKCPEGNNRVEKYAGLVADGRPYSEIERMYMGKTAINHFTKTALKGSLFTLAPVVKTCAEGIVFEGFIEGISKEDIEKIKKLRIGKYTSSGFGIACLSFGNSMENEKEDELREKAKQFSEKYKKIVKKDDFNFIALYFTSDILFKVDNLPAGYIPTQEYLKIFKNAIGIPEGFDIHRIFSQISVFRGVDTSKSDFTPKQIMYIAQAGTVLVLKTQKTIDEAVAELVKFKGFGEKIEDGYGWFEFYELKNS
>NC_015949.1|WP_014043420.1|2634403_2634946_-|hypothetical-protein
MKKITYKIEISLKSPLIVSSGETNSIMKSMIIGIDGKPIIPATTLKGIVRSNYIYLHHCQHKIFKCNCETCMLFGSQNNRSSLVFFEDLKPSEEYYVSIRTQTAIDRYRRAVHLNNLFSQKTIENTTFCGEISIYLPPDLEKQNVKEKFEQAVKFIEMIGSGKSRGLGHVKVCIEEVGDR
>NC_015949.1|WP_014043421.1|2634965_2636972_-|hypothetical-protein
MKIVSRENSKPVYSDNEKKSKKYLDQLYPVDGNYISSEELCKLKQLIEEMKDNQTLEELAEKNMSKKETELFDKRFEFSKSLDKNETAYLPALIDAAKIYVLVDFLTSVKESNIEQSTISFSRKDSYLKFLNPDSDDIIKQLLIEVMIETQKENNLSKQDYNQIKEKFKHHDKIMEILEIKIEVVKGGISKIKEYITEADKLAQMRGATELIKEANIERTREIINKAGLIPECLIYGSGGNSFIVVPKNKGQEICEKIEKEYSQLLLGGRFAFEFLEAELGEFLFDYSRLSTKITQKLTTRHIVRLPMLQSTSCQHETPNSVVPQDVKLCTTCWLRDPKKEIKIADEQHWVCDICYSKFAKSKNIRSSYHEEYCKFIGRNISYFKLPESLSEIDDYIALIYGDGNNLGNVIMNIRNVFELMYLSRRLDKITVSAVYEALKNAIEKESEGKENATAEKESKPLLKFEIIILGGEDILMIVPAKWALEVAKQIIEKFDTAFSNTITLSVGILITKSTMPMSAAYDFTVGLLKNAKKYVKKKKLEMGSVDVEVLTGSSILSKKGNKVIFPCEVERLEKILKAFKTIKEKLAKAKIYLFKEAAETLLPEEFELFYVFHKAREENIDAVEKAIQEMLDEDVKFVGGFVKKKDVDGKEQVILPWVEIAKLRDFI

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Crispr_ID: NC_015949_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_11

2627611-2628384

TypeI

Consensus_repeat	Method
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	PILER-CR
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	CRISPRCasFinder
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	CRT

11 spacers

cas3,cas5,cas7,cas8b1,cas2,cas1,cas4,csx20,csm6,csm2gr11,csm3gr7,csx10gr5,cas10,cas6

The CRISPR arrays of NC_015949_11

>merge|NC_015949|11|2627611-2628384|PILER-CR,CRISPRCasFinder,CRT
GTTTGTAGCCTGCCCTTTGGGGATTGAAACTTTAAATTTGCATTTAAATTAATCATTTGCTCTGTAGGTTTGTAGCCTGCCCTTTGGGGATTGAAACAAGCAAAATTTCTCTTTTTGCCCTCGCACATACCATGTTTGTAGCCTGCCCTTTGGGGATTGAAACACTTTTGCGTCTCTGACAGCTTGTCGTATAGCTTCAGTTTGTAGCCTGCCCTTTGGGGATTGAAACATTTTTAATTTAGACATCATTCTGCTTAATGACCCTAGTTTGTAGCCTGCCCTTTGGGGATTGAAACGCTGAAATTGGAACTAAACCTAATGAAACTTTGATTTTGTTTGTAGCCTGCCCTTTGGGGATTGAAACGCTTCTTTAAATAAATTGTATAAACTCTCTCTAAACTGTTTGTAGCCTGCCCTTTGGGGATTGAAACTTATTATACCCCTTTTCTTGCTTTTGTAAATACGTTTGTAGCCTGCCCTTTGGGGATTGAAACATGTTTGTTTGGTCAGCAGATGATGCCAAGAGCACTGTTTGTAGCCTGCCCTTTGGGGATTGAAACAATCCTCTTTTGCTTTTGTTTGTTAGCTTGGGTATAAGTTTGTAGCCTGCCCTTTGGGGATTGAAACAATGATTCTCAGTTCTTACGATGTCATAAGCATCATCTAGTTTGTAGCCTTCCCTTTGGGGATTGAGGAGAGAGGGGAATTTGTAGCCTTCTCTTTGGGGATTGAGGTGGGGCTGGGGGTTGCAGTCTGCTCTTGGAGGGATTGAGG

>NC_015949|11|8|2627611-2628237|PILER-CR
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTTAAATTTGCATTTAAATTAATCATTTGCTCTGTAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AAGCAAAATTTCTCTTTTTGCCCTCGCACATACCAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACTTTTGCGTCTCTGACAGCTTGTCGTATAGCTTCA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATTTTTAATTTAGACATCATTCTGCTTAATGACCCTA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTGAAATTGGAACTAAACCTAATGAAACTTTGATTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTTCTTTAAATAAATTGTATAAACTCTCTCTAAACT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTATTATACCCCTTTTCTTGCTTTTGTAAATAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATGTTTGTTTGGTCAGCAGATGATGCCAAGAGCACT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AATCCTCTTTTGCTTTTGTTTGTTAGCTTGGGTATAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC

>NC_015949|11|11|2627611-2628306|CRISPRCasFinder
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTTAAATTTGCATTTAAATTAATCATTTGCTCTGTAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AAGCAAAATTTCTCTTTTTGCCCTCGCACATACCAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACTTTTGCGTCTCTGACAGCTTGTCGTATAGCTTCA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATTTTTAATTTAGACATCATTCTGCTTAATGACCCTA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTGAAATTGGAACTAAACCTAATGAAACTTTGATTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTTCTTTAAATAAATTGTATAAACTCTCTCTAAACT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTATTATACCCCTTTTCTTGCTTTTGTAAATAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATGTTTGTTTGGTCAGCAGATGATGCCAAGAGCACT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AATCCTCTTTTGCTTTTGTTTGTTAGCTTGGGTATAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AATGATTCTCAGTTCTTACGATGTCATAAGCATCATCTA
GTTTGTAGCCTTCCCTTTGGGGATTGAGGA

>NC_015949|11|10|2627611-2628384|CRT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTTAAATTTGCATTTAAATTAATCATTTGCTCTGTAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AAGCAAAATTTCTCTTTTTGCCCTCGCACATACCAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACTTTTGCGTCTCTGACAGCTTGTCGTATAGCTTCA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATTTTTAATTTAGACATCATTCTGCTTAATGACCCTA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTGAAATTGGAACTAAACCTAATGAAACTTTGATTTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCTTCTTTAAATAAATTGTATAAACTCTCTCTAAACT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTATTATACCCCTTTTCTTGCTTTTGTAAATAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATGTTTGTTTGGTCAGCAGATGATGCCAAGAGCACT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AATCCTCTTTTGCTTTTGTTTGTTAGCTTGGGTATAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AATGATTCTCAGTTCTTACGATGTCATAAGCATCATCTA
GTTTGTAGCCTTCCCTTTGGGGATTGAGGA	GAGAGGGGAATTTGTAGCCTTCTCTTTGGGGATTGAGGTGGGGCTGGG
GGTTGCAGTCTGCTCTTGGAGGGATTGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_041725840.1\|2625756_2627148_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224586
NC_015949.1\|WP_014043416.1\|2631013_2631904_-\|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187814
NC_015949.1\|WP_014043419.1\|2633267_2634407_-\|hypothetical-protein	csx10gr5	cd09700_csx10gr5_CAS-III-D	gnl\|CDD\|187831
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl\|CDD\|187873
NC_015949.1\|WP_013433712.1\|2617314_2618310_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|187853
NC_015949.1\|WP_014043410.1\|2622361_2624830_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_015949.1\|WP_013433715.1\|2620652_2621633_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|187821
NC_015949.1\|WP_014043407.1\|2611321_2611729_-\|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_015949.1\|WP_013433710.1\|2616286_2616667_+\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043421.1\|2634965_2636972_-\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|274208
NC_015949.1\|WP_014043417.1\|2631945_2632728_-\|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274211
NC_015949.1\|WP_013433714.1\|2618665_2620588_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_015949.1\|WP_014043420.1\|2634403_2634946_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NC_015949.1\|WP_014043408.1\|2618325_2618589_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015949.1\|WP_014043414.1\|2629765_2630131_-\|hypothetical-protein	csm2gr11	mkCas0101_csm2gr11_CAS-III-D	unknown
NC_015949.1\|WP_013433711.1\|2616814_2617318_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_015949.1\|WP_014043418.1\|2632760_2633255_-\|hypothetical-protein	csm2gr11	mkCas0079_csm2gr11_CAS-III-D	unknown
NC_015949.1\|WP_014043415.1\|2630148_2631030_-\|hypothetical-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
NC_015949.1\|WP_014043422.1\|2637084_2637840_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|224499
NC_015949.1\|WP_014043409.1\|2621655_2622387_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015949.1\|WP_014043416.1\|2631013_2631904_-\|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	1e-31	104.8	0.3
NC_015949.1\|WP_014043419.1\|2633267_2634407_-\|hypothetical-protein	csx10gr5	cd09700_csx10gr5_CAS-III-D	2.2e-15	51.6	0.0
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	1.8e-20	67.7	0.2
NC_015949.1\|WP_013433712.1\|2617314_2618310_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	1.1e-137	453.1	13.8
NC_015949.1\|WP_014043407.1\|2611321_2611729_-\|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	2.6e-59	193.8	0.1
NC_015949.1\|WP_014043408.1\|2618325_2618589_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	5e-29	95.1	1.3
NC_015949.1\|WP_014043410.1\|2622361_2624830_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	3.6e-52	172.3	18.6
NC_015949.1\|WP_014043421.1\|2634965_2636972_-\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	1.8e-54	180.0	0.1
NC_015949.1\|WP_014043417.1\|2631945_2632728_-\|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	1.7e-45	149.8	0.0
NC_015949.1\|WP_013433714.1\|2618665_2620588_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	1.5e-109	362.0	27.3
NC_015949.1\|WP_014043420.1\|2634403_2634946_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	1.3e-19	66.1	0.0
NC_015949.1\|WP_013433715.1\|2620652_2621633_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	2e-85	281.3	0.1
NC_015949.1\|WP_014043414.1\|2629765_2630131_-\|hypothetical-protein	csm2gr11	mkCas0101_csm2gr11_CAS-III-D	1.6e-58	190.7	4.9
NC_015949.1\|WP_013433711.1\|2616814_2617318_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	4.5e-46	151.7	0.5
NC_015949.1\|WP_014043418.1\|2632760_2633255_-\|hypothetical-protein	csm2gr11	mkCas0079_csm2gr11_CAS-III-D	6.9e-52	169.7	8.9
NC_015949.1\|WP_014043415.1\|2630148_2631030_-\|hypothetical-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	1.1e-23	78.8	2.3
NC_015949.1\|WP_014043422.1\|2637084_2637840_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	3e-39	130.0	6.5
NC_015949.1\|WP_014043409.1\|2621655_2622387_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	2.1e-34	113.9	0.0

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_041725840.1\|2625756_2627148_-\|ATP-binding-protein	gnl\|CDD\|224586	COG1672, COG1672, Predicted ATPase (AAA+ superfamily) [General function prediction only].	2.46699e-30
NC_015949.1\|WP_014043417.1\|2631945_2632728_-\|CRISPR-associated-RAMP-protein	gnl\|CDD\|274211	TIGR02581, putative_CRISPR-associated_protein, CRISPR-associated RAMP protein, SSO1426 family. Members of this CRISPR-associated (cas) gene family are found in the RAMP-2 subtype of CRISPR/cas locus and designated TM1809 family.	5.94912e-42
NC_015949.1\|WP_014043419.1\|2633267_2634407_-\|hypothetical-protein	gnl\|CDD\|187831	cd09700, Csx10, CRISPR/Cas system-associated RAMP superfamily protein Csx10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Duplicated RAMP domains.	1.05984e-13
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	gnl\|CDD\|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	1.65162e-10
NC_015949.1\|WP_013433712.1\|2617314_2618310_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187853	cd09722, Cas1_I-B, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	5.1355e-168
NC_015949.1\|WP_014043410.1\|2622361_2624830_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	5.6921e-52
NC_015949.1\|WP_013433715.1\|2620652_2621633_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|187821	cd09690, Cas7_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csh2 family.	4.14483e-87
NC_015949.1\|WP_014043416.1\|2631013_2631904_-\|hypothetical-protein	gnl\|CDD\|187814	cd09683, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	5.46159e-25
NC_015949.1\|WP_014043421.1\|2634965_2636972_-\|hypothetical-protein	gnl\|CDD\|274208	TIGR02577, thermophile-specific_DNA_repair_system, CRISPR-associated protein Cas10/Cmr2, subtype III-B. This model represent a Crm2 family of the CRISPR-associated RAMP module, a set of six genes recurring found together in prokaryotic genomes. This gene cluster is found only in species with CRISPR repeats, usually near the repeats themselves. Because most of the six (but not this family) contain RAMP domains, and because its appearance in a genome appears to depend on other CRISPR-associated Cas genes, the set is designated the CRISPR RAMP module. This protein, typified by TM1794 from Thermotoga maritima, is designated Crm2, for CRISPR RAMP Module protein 2.	4.23072e-08
NC_015949.1\|WP_013433714.1\|2618665_2620588_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.4638e-106
NC_015949.1\|WP_014043420.1\|2634403_2634946_-\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	7.31705e-16
NC_015949.1\|WP_014043408.1\|2618325_2618589_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.87467e-29
NC_015949.1\|WP_013433711.1\|2616814_2617318_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.51721e-58
NC_015949.1\|WP_014043415.1\|2630148_2631030_-\|hypothetical-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	8.03721e-15
NC_015949.1\|WP_014043422.1\|2637084_2637840_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.13526e-28
NC_015949.1\|WP_014043409.1\|2621655_2622387_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	4.81053e-31

>NC_015949.1|WP_041725840.1|2625756_2627148_-|ATP-binding-protein
MKKFINRKHELDFLEKQYQEQKSSLVVIYGRRRIGKTALIKKFIEDKPTIYFLASEEVESQNIEYFKRTVSGFLKNPLIEKLSGISWDDIFDILVKTKSNKKIVIVLDEFQNLCKTNPAFASILQRIWDEKLKSGNFMLILCGSLISMMQEYALSYSSPLYGRRTGQIKLKQFSFKEAKEFFPDASDDEFIWIYSVVGGVPKYLEMFKYEGDIYKAIEENILSRQSFLYEEPLFLLEKEVHEIGSYFSIIKSIALGNHKLSQIAQSLSVPQTKLTKYLNTLIELDIIRREVPITEEYPEKSKRGLYFINDNFINFWFKFVYPYREQLELDNIEYVIENIRSKIVASHISYVYEEVCKQILSDLIRSEKIDVQIDKIGKWWDGKSEIDIVGIGRSMRHVVFGECKYSQNMIDIDVFFDLKKKAENVKVFPDQKEFYILFSKAGFSERLLEYAAEEKNIVLIKFP
>NC_015949.1|WP_014043410.1|2622361_2624830_+|CRISPR-associated-helicase/endonuclease-Cas3
MEKTSFCFDSKNLSGLFSHPGKDGSIQGAKPLEVHLTNTSILANCFASEKNIALCSTKFLSQIAKITALLHDIGKATSFFQKYLFDKKKTKSRHTRHSLISAICVWGTLNRLIEEKKIQEDKTFEGFTAILAFFATLKHHGDLEATSDMLLLSEDDIELCYEQIENIDKEKFNTLILNISCLCPEIGFLTIDSLREFVDHAKVSIKLFKRAFRKLFDTEMKFFFMLNLLYSILLDADKTEAIFGTLVDIPELNLSYIDVDSFRRRIFKPENFENSIKALRDSAFEEATNCEIDENRRIYTLCLPTGLGKTIISFAFALKLRELAQKRFSSKFRIIYSLPFLSIIEQNYDVISKILSFCGLDITSDILLKHHHLSDIVYKTKDGLQNNQEEIFDTDIAKLLIEGWNSNIIVTTFVQFLESIMTNKNSNMRKFHRIANSIIILDEVQAINSEYWFLCKNLFEKMCSSLNCFIILSTATMPFIVDKKTAVEIVKPEKYFDKLCRTVLHFDNNFSKIGLEEFVAKFEFEKEKTYLFVMNTVSSAKKLYELINQRFPDMQDEITILTTHIIPKERLRRIEQIKNKKYKIVVSTQLVEAGVDVDFDHVVRDIAPLDSIIQAAGRANREGKKGKSKVTVIELVSDRGRLFATEVYDSLLIDATKKILSQFQKVDESKFAELIFEYYKELARRGVIETSSDDKGTSQKFLEAIYRLLYTSSDSETDAIGSFKLIEDEPYKVDVFVEADEEAKIIWQRFEEICEIKDFFERKKKFLEIRKSFYDYIISVPKTTNLPVNFENLIFRIPHSQLSDFYDPITGFKTKGESYLSF
>NC_015949.1|WP_014043409.1|2621655_2622387_+|type-I-B-CRISPR-associated-protein-Cas5
MKVAVFDIKADFGFFGKFYSTSSPITYPFPPFPTIQGMVGAILGLDKKEYLDILEYGKFRAGIRILNPVKKIRMGINHIDTKEGRWQPIKTKNRQPRTQMRFELLKDPRFRIYATLATESLFSRLVEFLQQHRSYFTLSMGLSEFLADFEFVGVFEAVEKGMPNDYVSLCTPIPLSYLDSKAEIPLRIEAGKSYFKERMPLYMLSTREVVKYEDVIFEPTGKELLARPSSYVEVQNGENILLF
>NC_015949.1|WP_013433715.1|2620652_2621633_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MENAKEIIKNRSEVLFLYDVTDANPNGDPLDENKPRIDPETDTCIVTDVRLKRTCRDYWAEYKNLPVFILREISEDGKLMTKSDKFSKYNLSKEKLKDYIDIRLFGGTTTLKSKDEKKKSKSDEDLSEETGAITFTGPVQFKFGRSLHKVEYMLVKGTTVMPSGEGKDQGTFTECYILPYALIAFYGVVNENAALCQELPVTEEDIQLLLEALWCGTKNLISRSKFGQMPRLLVRVEYNQSGFYIGELDKLVKLISQKSDTAIRSPEDFQLDITRLVEKLTKHQDKIQKVQVSVDHSISFVCEGKFVHLKDALSFLGDRVKLLQFE
>NC_015949.1|WP_013433714.1|2618665_2620588_+|TIGR02556-family-CRISPR-associated-protein
MIEAVAEIGKFLIEKKSKASGKSCADDQSNNLSSFLTPVESEKVILICLKQKQTEFEYCGLDLQNPLVSRAQLYLFSQGAKGGGTNYSPVCILTKPKTPKTMTEEQVKQATKEQVEKVFKQKVENWFLNKALPLAKKFSKQGDISKEDAYFIQCISQAVSENREKIIEDISELLFEVEFEKQKSSALLTFSIDGKYIGEYEIFKSFLLELIKEKAERSSSQDKTCSICKQKRENVSGTVNVFKFYTIDKPGFIRGGFSSENAWKNFPVCSSCQIHLSEGRKYLEKELQFKFYNFKYLLIPQLIFSTSSAYSEVLDILQNTKKEISLGEKALERITDDENEILDVISTFNDSISVTFLFMVPQMGAERIVLMIEDVLPSHLKNIFDAKRHTERKYRTVFNNPDINFTFQQIKHFFSKSNRLKKKSDLDSYFLEITESIFKKKPIDFQFLAAHFCRRLQDSIANKDFFDFYTSCSYAIEVLEFLNKLEILKLKGDEFGMSYETPFDEILNEFPVASANPAVKGIILVGALCDILMRIQSTALSKTPGKMPPFAKNLKGLRLKQSDIVSLLPKIENKLMEYSSFGKANRLIASSASELLLKSPVDWKLSADEVSFYFACGMNLGQKIREHAKKLTGDTDEQEA
>NC_015949.1|WP_014043408.1|2618325_2618589_+|CRISPR-associated-endonuclease-Cas2
MYTILVYDVNEKRVAKALKVCRKYLNWVQNSVFEGEISEAKLKKLKFELSQKLNLHEDSVIIYNFQSRLYSQREILGVEKNNLDRFI
>NC_015949.1|WP_013433712.1|2617314_2618310_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKRPIYIFSDGVLKRKNNTLYFESEGVQKFIPVENTSEIYIFGEVELNKRFLEFLTQSEIILHFFNRYGYYVGSFYPREYLNSGYMILKQAEHYLDTQKRLSLARTFVEGSYKNMRQVLKYYQSRGIDELERYIQQMENLFGSISNINDINTLMAIEGNIRQTYYSAFDLIIDKDDFKFEKRSKRPPKNALNALISFGNSMMYTIVLSEIYRTHLDPRIGYLHTTNFRRFTLNLDVAEIFKPIIVDRLIFSIISKNMLKPEHFEQNLEGIVITDSAKKLFIDELEQRLSTTISVKNIGNYVSYRQLIRIELYKIEKHLMGEKEYQPYVSQW
>NC_015949.1|WP_013433711.1|2616814_2617318_+|CRISPR-associated-protein-Cas4
MERFLDIKGHIVQAYVVCKRQAWLLSRNISPVQDNPFLEIGKLISQQFYKHDKKEVYFDGVVLDLIRKEDEVLVVGEIKKSSKKVAAAILQLKFYLYKLLKHNIKARGKLLIPEEKKTYDVELTFEDIETIESLLSEITEVLSSFLPPLPQKIKACAKCSYKEFCWA
>NC_015949.1|WP_013433710.1|2616286_2616667_+|hypothetical-protein
MSYLPKSPKEVYEQILLEYQAYSEFKKRIEGKCYLPHDPENVLYLYCNSTFNEEYEEMLKSKQIENYVEPQTEEEWEYYAEEDEYCKEEFENDFEFFDADYEMSSEMDDIVDDPDFWDSFDYEWGD
>NC_015949.1|WP_014043407.1|2611321_2611729_-|hypothetical-protein
MVILNKLFLIFNHQLSEEQEKEAREVLKVEEIVSLPPQLQDFWSSIPPDVELTEEMFEDITAFLLQNRGEKENFCLVQGDFGATVYIVSWCFKNGFVPIYATTKRVSKEIVRPDGSVELHKVFKHERFRKYILCR
>NC_015949.1|WP_014043413.1|2628542_2629748_-|putative-CRISPR-associated-protein
MPKYSNIVMTGGISAFNSSNVFYQYFAEFIENKSSYAGQNLEKVLEEICKEKGLTDKELERLVKERPNQISAEFSMLKGLKEKDLLDDIINISVIHSDTPDGIMAALINKKVIELVFKDSTVSLEKVEDVDISNEVKLQRSLGYFMKIVANELLKGTKETTFFAPIGGYKYMAYLGYVAGALFGYSSGYMYEKGQKLLTIPPIPIEINFDLITKNKNFIRNLLTEGQLNYQSLSPDEKEIVDTMPYFFEKVEIDGQEIVSANAFAEFIFGDYISTAVKVSPEVSDLISKNEQYRNFILNQLMGLIKKANSFFKDYRNYQGLRGELMHNENWGIDRPYLYKGSSNGNKLVFRCAYDFDYKSRILYIYKIWLNHDKYEREAEAIKNGKITIDMDKNKMFELEY
>NC_015949.1|WP_014043414.1|2629765_2630131_-|hypothetical-protein
MKDKKELLEIAKKIESELSSSNSSFISDIVSFIIASKIEKNSKEEQLKRFLEFLWFCTKNPNVLGGGNTKKNGFKKFIEDYLKLKKENGNFILGNGDFSCLDIDDLFFVFAWAKRIVKSSR
>NC_015949.1|WP_014043415.1|2630148_2631030_-|hypothetical-protein
MSKSYSFIAFLETKENYNNSYTTKLSAELLKYEKLRLQIETLSYLHIWSGMYSEKNGLIYRTFIKSNGKYIIPGSSLKGCVRTVAEMVSYSCMGVATNEQTKVKIPVKKWHSDKRKRCIVCDMFGAPGNKSKLIFHDFAVVSVEDYSKITELICIPPSFEPHPPECDDYKDENGNFKGYKIYNHGEFKSASPDNGIWIEAVKPGVRFEGEIWLRADLKQEQKELLCFSLGLSGFDLKIGYGKNHYLGSIRIGAVNGSSELIDLAKKYEAKADDKVKNNIMKIKEIWQFKNEKV
>NC_015949.1|WP_014043416.1|2631013_2631904_-|hypothetical-protein
MFKKLLNQAIVNFELVTQSPLYIKQNTSLLDPTAFDGTYISCYLDDQRIPIIPGTSMKGVFRSFFEKMLGEEACDILDTRQDSNKCLKTIKEYEEKLKSSNKKDKTNNFDEELEKLKDFSRGKLNYYLSCPACKVFGSQRLKSRMLFDDAKAKEGFKISSRSSTPIDRISGAAKEKGLNTFEYVDWGVFEAKITLVNFFNWQLKLLLEIFERIDEGILMFGGYSSKGFGRMKVENVTIKVRYYGEMKGKAKDGYSQNALFAERVFNNKEVKEKLQSIDFLDKNQWAKVELKDEQIL
>NC_015949.1|WP_014043417.1|2631945_2632728_-|CRISPR-associated-RAMP-protein
MLLFDKFENRYIIKGIITNLNPIHIGAGGASFNPLEVDNRIVRYASTNEPYIPGSSLKGVLRSFFEQIYPKEHCWATINPCSKKKEKEIEDKRKKYSENPEGYAKEVYSLLCDICKVFGSQETASKIYISDLKVREENGKKLYKLGVRDGVGIDRDTGTAANRMKYDFEVIEPGAKFDLYMVFENLENEYVKSFLIPIVEVLKSGELKIGGKTSRGLGRIKLLEDFKIYKITKDNIKNYLEKGLNEIEPLSWADFKKQFE
>NC_015949.1|WP_014043418.1|2632760_2633255_-|hypothetical-protein
MKEEARKEIIKMLVQWADKIGENKNFWKQNRELGKTNIRTTATAILQASCYNEVKLFLEYKGSRKNTGWDKLFNNNTTFANYIISKIEDLRKKVDEKYKEDPTFDKEKEVIELAARFLGYIYWKIYGLVNQKENEERQPQNSNQSPQMKGTNYQGRSGSRQSRS
>NC_015949.1|WP_014043419.1|2633267_2634407_-|hypothetical-protein
MKVYLNFKSPVLVGGRKSATNFIESINYIPGSVVRAALAKFVVLNCKAQRDVYGESSEKRFWVEFKNKEECQRCEFTNLCKNFNEIKISFFYPKGAKPNPLCDMICKNNEDHGFYSELLYGSEDKEAKCLKCPEGNNRVEKYAGLVADGRPYSEIERMYMGKTAINHFTKTALKGSLFTLAPVVKTCAEGIVFEGFIEGISKEDIEKIKKLRIGKYTSSGFGIACLSFGNSMENEKEDELREKAKQFSEKYKKIVKKDDFNFIALYFTSDILFKVDNLPAGYIPTQEYLKIFKNAIGIPEGFDIHRIFSQISVFRGVDTSKSDFTPKQIMYIAQAGTVLVLKTQKTIDEAVAELVKFKGFGEKIEDGYGWFEFYELKNS
>NC_015949.1|WP_014043420.1|2634403_2634946_-|hypothetical-protein
MKKITYKIEISLKSPLIVSSGETNSIMKSMIIGIDGKPIIPATTLKGIVRSNYIYLHHCQHKIFKCNCETCMLFGSQNNRSSLVFFEDLKPSEEYYVSIRTQTAIDRYRRAVHLNNLFSQKTIENTTFCGEISIYLPPDLEKQNVKEKFEQAVKFIEMIGSGKSRGLGHVKVCIEEVGDR
>NC_015949.1|WP_014043421.1|2634965_2636972_-|hypothetical-protein
MKIVSRENSKPVYSDNEKKSKKYLDQLYPVDGNYISSEELCKLKQLIEEMKDNQTLEELAEKNMSKKETELFDKRFEFSKSLDKNETAYLPALIDAAKIYVLVDFLTSVKESNIEQSTISFSRKDSYLKFLNPDSDDIIKQLLIEVMIETQKENNLSKQDYNQIKEKFKHHDKIMEILEIKIEVVKGGISKIKEYITEADKLAQMRGATELIKEANIERTREIINKAGLIPECLIYGSGGNSFIVVPKNKGQEICEKIEKEYSQLLLGGRFAFEFLEAELGEFLFDYSRLSTKITQKLTTRHIVRLPMLQSTSCQHETPNSVVPQDVKLCTTCWLRDPKKEIKIADEQHWVCDICYSKFAKSKNIRSSYHEEYCKFIGRNISYFKLPESLSEIDDYIALIYGDGNNLGNVIMNIRNVFELMYLSRRLDKITVSAVYEALKNAIEKESEGKENATAEKESKPLLKFEIIILGGEDILMIVPAKWALEVAKQIIEKFDTAFSNTITLSVGILITKSTMPMSAAYDFTVGLLKNAKKYVKKKKLEMGSVDVEVLTGSSILSKKGNKVIFPCEVERLEKILKAFKTIKEKLAKAKIYLFKEAAETLLPEEFELFYVFHKAREENIDAVEKAIQEMLDEDVKFVGGFVKKKDVDGKEQVILPWVEIAKLRDFI
>NC_015949.1|WP_014043422.1|2637084_2637840_-|CRISPR-associated-endoribonuclease-Cas6
MRFKLKLTNEKETIIKVDYFIELASSINMLLDSNYLRYIENGAYLLNRKIYKPWTFSRLFFEKYSFANKEIRVLPGDSYLIVSTIDDNFAYFFLKGILKEKCLRVGEAIFEVRSVSVLNQPQRKQIVCRTLSPIIIKEIQRIENSCPEFAASFVEGVKKNLVSKAKAFRNINISPEKIEIQIVNNEKIKRKTLRIKNEFYVGYELLLKIKSLPEIIEIAYNCGLGVKNALGFGCVEIIPPPSERVLISFEK

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Crispr_ID: NC_015949_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015949_12

2638696-2639991

TypeIII

Consensus_repeat	Method
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	PILER-CR
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	CRISPRCasFinder
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	CRT

19 spacers

cas6,cas10,csm3gr7,csx10gr5,csm2gr11,csm6,WYL

The CRISPR arrays of NC_015949_12

>merge|NC_015949|12|2638696-2639991|PILER-CR,CRISPRCasFinder,CRT
GTTTGTAGCCTGCCCTTTGGGGATTGAAACTGTCTTGGGATGATAATATCTACGACAGTGTAAATGTGTTTGTAGCCTGCCCTTTGGGGATTGAAACACTGCTTCAGCTGCTGTTTCTTTAGCTGCTTTAACAACGTTTGTAGCCTGCCCTTTGGGGATTGAAACATCCATTGCTCTTGTTTTCTTGCTTTATCAACTCTGGTTTGTAGCCTGCCCTTTGGGGATTGAAACAGAGCTTTCGCGGCATAAACGGTTTCCCCCCCGCAAGGTTTGTAGCCTGCCCTTTGGGGATTGAAACTTTGGTTTTCATTATTTTATATCATTTTAAAAATCTTCGTTTGTAGCCTGCCCTTTGGGGATTGAAACATTTTATACTCTTGCTGTATTTAGTTAAAAAACATGTTTGTAGCCTGCCCTTTGGGGATTGAAACGATTATTTTCACAGAGAATATAAATTCTTCTTATTTGTTTGTAGCCTGCCCTTTGGGGATTGAAACTAGCTTCTTCTACTTTATTATGTTGATTATACCCAAGTTTGTAGCCTGCCCTTTGGGGATTGAAACGCAAATCTCTTCTCAGGTCTATACGCTTCAACCTTCTCGTTTGTAGCCTGCCCTTTGGGGATTGAAACTTACTTGAACTAATTTATTATTAAGCTCTCTAACTATGTTTGTAGCCTGCCCTTTGGGGATTGAAACTGACAATGCAATGTAAAAAAAAGACTAACCAAAAAAGTTTGTAGCCTGCCCTTTGGGGATTGAAACATTTTTTAACGATGCATTCCTGAACAATAATTACAAGTTTGTAGCCTGCCCTTTGGGGATTGAAACAGCCCTTTTTAAAAAAATTTTAAAAATTTTTTTCTTGTTTGTAACCTGCCCTTTGGGGATTGAAACAGACGACTTATATTCTGAGCTATGAACATATAATCGTTTGTAGCCTGCCCTTTGGGGATTGAAACAACAGTAACAATTACATAGCCTATAATACCTAAACGTTTGTAGCCTGCCCTTTGGGGATTGAAACTAATGTTTAAGCGGCTCGCAATTGCGAGCCGCCGCTTGTTTGTAGCCTGCCCTTTGGGGATTGAAACGTAAAAGTCCCTTCAGCTTCTTTAAATCCAAAACTTTCGTTTGTAGCCTGCCCTTTGGGGATTGAAACACATTTAGTAATAACTCCACCGTCCCCTCTTGCGGGTTGTTTGTAGCCTGCCCTTTGGGGATTGAAACGGATACTTTTCATGGAATGCTAATCTTATGTATGCTTGTTTGTAGCCTGCCCTTTGGGGATTGAAAC

>NC_015949|12|9|2638696-2639991|PILER-CR
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TGTCTTGGGATGATAATATCTACGACAGTGTAAATGT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACTGCTTCAGCTGCTGTTTCTTTAGCTGCTTTAACAAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATCCATTGCTCTTGTTTTCTTGCTTTATCAACTCTG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AGAGCTTTCGCGGCATAAACGGTTTCCCCCCCGCAAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTTGGTTTTCATTATTTTATATCATTTTAAAAATCTTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATTTTATACTCTTGCTGTATTTAGTTAAAAAACAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GATTATTTTCACAGAGAATATAAATTCTTCTTATTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAGCTTCTTCTACTTTATTATGTTGATTATACCCAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCAAATCTCTTCTCAGGTCTATACGCTTCAACCTTCTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTACTTGAACTAATTTATTATTAAGCTCTCTAACTAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TGACAATGCAATGTAAAAAAAAGACTAACCAAAAAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATTTTTTAACGATGCATTCCTGAACAATAATTACAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AGCCCTTTTTAAAAAAATTTTAAAAATTTTTTTCTT
GTTTGTAACCTGCCCTTTGGGGATTGAAAC	AGACGACTTATATTCTGAGCTATGAACATATAATC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AACAGTAACAATTACATAGCCTATAATACCTAAAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAATGTTTAAGCGGCTCGCAATTGCGAGCCGCCGCTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GTAAAAGTCCCTTCAGCTTCTTTAAATCCAAAACTTTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACATTTAGTAATAACTCCACCGTCCCCTCTTGCGGGTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GGATACTTTTCATGGAATGCTAATCTTATGTATGCTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC

>NC_015949|12|12|2638696-2639991|CRISPRCasFinder
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TGTCTTGGGATGATAATATCTACGACAGTGTAAATGT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACTGCTTCAGCTGCTGTTTCTTTAGCTGCTTTAACAAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATCCATTGCTCTTGTTTTCTTGCTTTATCAACTCTG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AGAGCTTTCGCGGCATAAACGGTTTCCCCCCCGCAAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTTGGTTTTCATTATTTTATATCATTTTAAAAATCTTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATTTTATACTCTTGCTGTATTTAGTTAAAAAACAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GATTATTTTCACAGAGAATATAAATTCTTCTTATTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAGCTTCTTCTACTTTATTATGTTGATTATACCCAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCAAATCTCTTCTCAGGTCTATACGCTTCAACCTTCTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTACTTGAACTAATTTATTATTAAGCTCTCTAACTAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TGACAATGCAATGTAAAAAAAAGACTAACCAAAAAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATTTTTTAACGATGCATTCCTGAACAATAATTACAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AGCCCTTTTTAAAAAAATTTTAAAAATTTTTTTCTT
GTTTGTAACCTGCCCTTTGGGGATTGAAAC	AGACGACTTATATTCTGAGCTATGAACATATAATC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AACAGTAACAATTACATAGCCTATAATACCTAAAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAATGTTTAAGCGGCTCGCAATTGCGAGCCGCCGCTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GTAAAAGTCCCTTCAGCTTCTTTAAATCCAAAACTTTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACATTTAGTAATAACTCCACCGTCCCCTCTTGCGGGTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GGATACTTTTCATGGAATGCTAATCTTATGTATGCTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC

>NC_015949|12|11|2638696-2639991|CRT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TGTCTTGGGATGATAATATCTACGACAGTGTAAATGT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACTGCTTCAGCTGCTGTTTCTTTAGCTGCTTTAACAAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATCCATTGCTCTTGTTTTCTTGCTTTATCAACTCTG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AGAGCTTTCGCGGCATAAACGGTTTCCCCCCCGCAAG
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTTGGTTTTCATTATTTTATATCATTTTAAAAATCTTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATTTTATACTCTTGCTGTATTTAGTTAAAAAACAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GATTATTTTCACAGAGAATATAAATTCTTCTTATTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAGCTTCTTCTACTTTATTATGTTGATTATACCCAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GCAAATCTCTTCTCAGGTCTATACGCTTCAACCTTCTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TTACTTGAACTAATTTATTATTAAGCTCTCTAACTAT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TGACAATGCAATGTAAAAAAAAGACTAACCAAAAAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ATTTTTTAACGATGCATTCCTGAACAATAATTACAA
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AGCCCTTTTTAAAAAAATTTTAAAAATTTTTTTCTT
GTTTGTAACCTGCCCTTTGGGGATTGAAAC	AGACGACTTATATTCTGAGCTATGAACATATAATC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	AACAGTAACAATTACATAGCCTATAATACCTAAAC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	TAATGTTTAAGCGGCTCGCAATTGCGAGCCGCCGCTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GTAAAAGTCCCTTCAGCTTCTTTAAATCCAAAACTTTC
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	ACATTTAGTAATAACTCCACCGTCCCCTCTTGCGGGTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC	GGATACTTTTCATGGAATGCTAATCTTATGTATGCTT
GTTTGTAGCCTGCCCTTTGGGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015949.1\|WP_013433740.1\|2645718_2646114_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_013404418.1\|2645355_2645616_+\|stage-V-sporulation-protein-S	unknown	unknown	gnl\|CDD\|377254
NC_015949.1\|WP_014043429.1\|2646277_2649328_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl\|CDD\|187873
NC_015949.1\|WP_014043417.1\|2631945_2632728_-\|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274211
NC_015949.1\|WP_014043415.1\|2630148_2631030_-\|hypothetical-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|377130
NC_015949.1\|WP_014043416.1\|2631013_2631904_-\|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187814
NC_015949.1\|WP_014043431.1\|2650392_2651706_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_015949.1\|WP_014043421.1\|2634965_2636972_-\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|274208
NC_015949.1\|WP_014043425.1\|2642098_2642929_+\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043430.1\|2649401_2650409_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_015949.1\|WP_014043427.1\|2643926_2644394_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043428.1\|2644463_2645162_-\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043420.1\|2634403_2634946_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NC_015949.1\|WP_014043419.1\|2633267_2634407_-\|hypothetical-protein	csx10gr5	cd09700_csx10gr5_CAS-III-D	gnl\|CDD\|187831
NC_015949.1\|WP_014043414.1\|2629765_2630131_-\|hypothetical-protein	csm2gr11	mkCas0101_csm2gr11_CAS-III-D	unknown
NC_015949.1\|WP_014043418.1\|2632760_2633255_-\|hypothetical-protein	csm2gr11	mkCas0079_csm2gr11_CAS-III-D	unknown
NC_015949.1\|WP_014043424.1\|2641089_2641605_+\|hypothetical-protein	unknown	unknown	unknown
NC_015949.1\|WP_014043422.1\|2637084_2637840_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|224499
NC_015949.1\|WP_041725842.1\|2643019_2643847_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	1.8e-20	67.7	0.2
NC_015949.1\|WP_014043417.1\|2631945_2632728_-\|CRISPR-associated-RAMP-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	1.7e-45	149.8	0.0
NC_015949.1\|WP_014043416.1\|2631013_2631904_-\|hypothetical-protein	csm3gr7	cd09683_csm3gr7_CAS-III-A:CAS-III-D	1e-31	104.8	0.3
NC_015949.1\|WP_014043431.1\|2650392_2651706_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	2e-22	74.7	2.8
NC_015949.1\|WP_014043421.1\|2634965_2636972_-\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	1.8e-54	180.0	0.1
NC_015949.1\|WP_014043414.1\|2629765_2630131_-\|hypothetical-protein	csm2gr11	mkCas0101_csm2gr11_CAS-III-D	1.6e-58	190.7	4.9
NC_015949.1\|WP_014043420.1\|2634403_2634946_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	1.3e-19	66.1	0.0
NC_015949.1\|WP_014043419.1\|2633267_2634407_-\|hypothetical-protein	csx10gr5	cd09700_csx10gr5_CAS-III-D	2.2e-15	51.6	0.0
NC_015949.1\|WP_014043430.1\|2649401_2650409_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	1.8e-14	48.8	1.2
NC_015949.1\|WP_014043418.1\|2632760_2633255_-\|hypothetical-protein	csm2gr11	mkCas0079_csm2gr11_CAS-III-D	6.9e-52	169.7	8.9
NC_015949.1\|WP_014043415.1\|2630148_2631030_-\|hypothetical-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	1.1e-23	78.8	2.3
NC_015949.1\|WP_014043422.1\|2637084_2637840_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	3e-39	130.0	6.5

Protein	Function_ID	Function_description	E-value
NC_015949.1\|WP_014043417.1\|2631945_2632728_-\|CRISPR-associated-RAMP-protein	gnl\|CDD\|274211	TIGR02581, putative_CRISPR-associated_protein, CRISPR-associated RAMP protein, SSO1426 family. Members of this CRISPR-associated (cas) gene family are found in the RAMP-2 subtype of CRISPR/cas locus and designated TM1809 family.	5.94912e-42
NC_015949.1\|WP_014043413.1\|2628542_2629748_-\|putative-CRISPR-associated-protein	gnl\|CDD\|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	1.65162e-10
NC_015949.1\|WP_014043429.1\|2646277_2649328_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	3.87102e-105
NC_015949.1\|WP_014043416.1\|2631013_2631904_-\|hypothetical-protein	gnl\|CDD\|187814	cd09683, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	5.46159e-25
NC_015949.1\|WP_014043431.1\|2650392_2651706_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	9.51502e-13
NC_015949.1\|WP_014043421.1\|2634965_2636972_-\|hypothetical-protein	gnl\|CDD\|274208	TIGR02577, thermophile-specific_DNA_repair_system, CRISPR-associated protein Cas10/Cmr2, subtype III-B. This model represent a Crm2 family of the CRISPR-associated RAMP module, a set of six genes recurring found together in prokaryotic genomes. This gene cluster is found only in species with CRISPR repeats, usually near the repeats themselves. Because most of the six (but not this family) contain RAMP domains, and because its appearance in a genome appears to depend on other CRISPR-associated Cas genes, the set is designated the CRISPR RAMP module. This protein, typified by TM1794 from Thermotoga maritima, is designated Crm2, for CRISPR RAMP Module protein 2.	4.23072e-08
NC_015949.1\|WP_014043420.1\|2634403_2634946_-\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	7.31705e-16
NC_015949.1\|WP_014043419.1\|2633267_2634407_-\|hypothetical-protein	gnl\|CDD\|187831	cd09700, Csx10, CRISPR/Cas system-associated RAMP superfamily protein Csx10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Duplicated RAMP domains.	1.05984e-13
NC_015949.1\|WP_014043430.1\|2649401_2650409_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	2.06737e-09
NC_015949.1\|WP_014043415.1\|2630148_2631030_-\|hypothetical-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	8.03721e-15
NC_015949.1\|WP_014043422.1\|2637084_2637840_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|224499	COG1583, COG1583, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	1.13526e-28
NC_015949.1\|WP_013404418.1\|2645355_2645616_+\|stage-V-sporulation-protein-S	gnl\|CDD\|377254	pfam04232, SpoVS, Stage V sporulation protein S (SpoVS). In Bacillus subtilis this protein interferes with sporulation at an early stage and this inhibitory effect is overcome by SpoIIB and SpoVG. SpoVS seems to play a positive role in allowing progression beyond stage V of sporulation. Null mutations in the spoVS gene block sporulation at stage V, impairing the development of heat resistance and coat assembly.	2.14095e-35

>NC_015949.1|WP_014043422.1|2637084_2637840_-|CRISPR-associated-endoribonuclease-Cas6
MRFKLKLTNEKETIIKVDYFIELASSINMLLDSNYLRYIENGAYLLNRKIYKPWTFSRLFFEKYSFANKEIRVLPGDSYLIVSTIDDNFAYFFLKGILKEKCLRVGEAIFEVRSVSVLNQPQRKQIVCRTLSPIIIKEIQRIENSCPEFAASFVEGVKKNLVSKAKAFRNINISPEKIEIQIVNNEKIKRKTLRIKNEFYVGYELLLKIKSLPEIIEIAYNCGLGVKNALGFGCVEIIPPPSERVLISFEK
>NC_015949.1|WP_014043421.1|2634965_2636972_-|hypothetical-protein
MKIVSRENSKPVYSDNEKKSKKYLDQLYPVDGNYISSEELCKLKQLIEEMKDNQTLEELAEKNMSKKETELFDKRFEFSKSLDKNETAYLPALIDAAKIYVLVDFLTSVKESNIEQSTISFSRKDSYLKFLNPDSDDIIKQLLIEVMIETQKENNLSKQDYNQIKEKFKHHDKIMEILEIKIEVVKGGISKIKEYITEADKLAQMRGATELIKEANIERTREIINKAGLIPECLIYGSGGNSFIVVPKNKGQEICEKIEKEYSQLLLGGRFAFEFLEAELGEFLFDYSRLSTKITQKLTTRHIVRLPMLQSTSCQHETPNSVVPQDVKLCTTCWLRDPKKEIKIADEQHWVCDICYSKFAKSKNIRSSYHEEYCKFIGRNISYFKLPESLSEIDDYIALIYGDGNNLGNVIMNIRNVFELMYLSRRLDKITVSAVYEALKNAIEKESEGKENATAEKESKPLLKFEIIILGGEDILMIVPAKWALEVAKQIIEKFDTAFSNTITLSVGILITKSTMPMSAAYDFTVGLLKNAKKYVKKKKLEMGSVDVEVLTGSSILSKKGNKVIFPCEVERLEKILKAFKTIKEKLAKAKIYLFKEAAETLLPEEFELFYVFHKAREENIDAVEKAIQEMLDEDVKFVGGFVKKKDVDGKEQVILPWVEIAKLRDFI
>NC_015949.1|WP_014043420.1|2634403_2634946_-|hypothetical-protein
MKKITYKIEISLKSPLIVSSGETNSIMKSMIIGIDGKPIIPATTLKGIVRSNYIYLHHCQHKIFKCNCETCMLFGSQNNRSSLVFFEDLKPSEEYYVSIRTQTAIDRYRRAVHLNNLFSQKTIENTTFCGEISIYLPPDLEKQNVKEKFEQAVKFIEMIGSGKSRGLGHVKVCIEEVGDR
>NC_015949.1|WP_014043419.1|2633267_2634407_-|hypothetical-protein
MKVYLNFKSPVLVGGRKSATNFIESINYIPGSVVRAALAKFVVLNCKAQRDVYGESSEKRFWVEFKNKEECQRCEFTNLCKNFNEIKISFFYPKGAKPNPLCDMICKNNEDHGFYSELLYGSEDKEAKCLKCPEGNNRVEKYAGLVADGRPYSEIERMYMGKTAINHFTKTALKGSLFTLAPVVKTCAEGIVFEGFIEGISKEDIEKIKKLRIGKYTSSGFGIACLSFGNSMENEKEDELREKAKQFSEKYKKIVKKDDFNFIALYFTSDILFKVDNLPAGYIPTQEYLKIFKNAIGIPEGFDIHRIFSQISVFRGVDTSKSDFTPKQIMYIAQAGTVLVLKTQKTIDEAVAELVKFKGFGEKIEDGYGWFEFYELKNS
>NC_015949.1|WP_014043418.1|2632760_2633255_-|hypothetical-protein
MKEEARKEIIKMLVQWADKIGENKNFWKQNRELGKTNIRTTATAILQASCYNEVKLFLEYKGSRKNTGWDKLFNNNTTFANYIISKIEDLRKKVDEKYKEDPTFDKEKEVIELAARFLGYIYWKIYGLVNQKENEERQPQNSNQSPQMKGTNYQGRSGSRQSRS
>NC_015949.1|WP_014043417.1|2631945_2632728_-|CRISPR-associated-RAMP-protein
MLLFDKFENRYIIKGIITNLNPIHIGAGGASFNPLEVDNRIVRYASTNEPYIPGSSLKGVLRSFFEQIYPKEHCWATINPCSKKKEKEIEDKRKKYSENPEGYAKEVYSLLCDICKVFGSQETASKIYISDLKVREENGKKLYKLGVRDGVGIDRDTGTAANRMKYDFEVIEPGAKFDLYMVFENLENEYVKSFLIPIVEVLKSGELKIGGKTSRGLGRIKLLEDFKIYKITKDNIKNYLEKGLNEIEPLSWADFKKQFE
>NC_015949.1|WP_014043416.1|2631013_2631904_-|hypothetical-protein
MFKKLLNQAIVNFELVTQSPLYIKQNTSLLDPTAFDGTYISCYLDDQRIPIIPGTSMKGVFRSFFEKMLGEEACDILDTRQDSNKCLKTIKEYEEKLKSSNKKDKTNNFDEELEKLKDFSRGKLNYYLSCPACKVFGSQRLKSRMLFDDAKAKEGFKISSRSSTPIDRISGAAKEKGLNTFEYVDWGVFEAKITLVNFFNWQLKLLLEIFERIDEGILMFGGYSSKGFGRMKVENVTIKVRYYGEMKGKAKDGYSQNALFAERVFNNKEVKEKLQSIDFLDKNQWAKVELKDEQIL
>NC_015949.1|WP_014043415.1|2630148_2631030_-|hypothetical-protein
MSKSYSFIAFLETKENYNNSYTTKLSAELLKYEKLRLQIETLSYLHIWSGMYSEKNGLIYRTFIKSNGKYIIPGSSLKGCVRTVAEMVSYSCMGVATNEQTKVKIPVKKWHSDKRKRCIVCDMFGAPGNKSKLIFHDFAVVSVEDYSKITELICIPPSFEPHPPECDDYKDENGNFKGYKIYNHGEFKSASPDNGIWIEAVKPGVRFEGEIWLRADLKQEQKELLCFSLGLSGFDLKIGYGKNHYLGSIRIGAVNGSSELIDLAKKYEAKADDKVKNNIMKIKEIWQFKNEKV
>NC_015949.1|WP_014043414.1|2629765_2630131_-|hypothetical-protein
MKDKKELLEIAKKIESELSSSNSSFISDIVSFIIASKIEKNSKEEQLKRFLEFLWFCTKNPNVLGGGNTKKNGFKKFIEDYLKLKKENGNFILGNGDFSCLDIDDLFFVFAWAKRIVKSSR
>NC_015949.1|WP_014043413.1|2628542_2629748_-|putative-CRISPR-associated-protein
MPKYSNIVMTGGISAFNSSNVFYQYFAEFIENKSSYAGQNLEKVLEEICKEKGLTDKELERLVKERPNQISAEFSMLKGLKEKDLLDDIINISVIHSDTPDGIMAALINKKVIELVFKDSTVSLEKVEDVDISNEVKLQRSLGYFMKIVANELLKGTKETTFFAPIGGYKYMAYLGYVAGALFGYSSGYMYEKGQKLLTIPPIPIEINFDLITKNKNFIRNLLTEGQLNYQSLSPDEKEIVDTMPYFFEKVEIDGQEIVSANAFAEFIFGDYISTAVKVSPEVSDLISKNEQYRNFILNQLMGLIKKANSFFKDYRNYQGLRGELMHNENWGIDRPYLYKGSSNGNKLVFRCAYDFDYKSRILYIYKIWLNHDKYEREAEAIKNGKITIDMDKNKMFELEY
>NC_015949.1|WP_014043424.1|2641089_2641605_+|hypothetical-protein
MQIRVRQYVLQENGLDSWWDFRMPYEDYLVTLPELLIQLKHYRFSMKLFNVVPRYTKVLFFKNGICLVYRFGMLITKRDPNLPLTDLNCPTEVINYDGREWYIEEFGSALVIGNVDANKLKAKLDKFEKRWKRNYYKTRKRDIQICIKNLQNRDPELDDRILEIYQKVTEE
>NC_015949.1|WP_014043425.1|2642098_2642929_+|hypothetical-protein
MDTVIHLDFLKEFDEAPLIERIGEYLRTFMSLRELLKDEPGNFKRPKEYLYFKQCPGWLGACPHGKKERDKKCDPTKCWNMKYGDVKNRIPKLEDLNYDNILIKVLSPAVCPDCGNNKLKLVWGKKVDVKVAGHTVTFDDVAYLRCDKCGKVHMSNQDKKAIEVIKEKIRTYDPYSNVIEDPDEELIELGYNPEAEIREFPETATIHLTKDKVALDLFMDDGISHSTSLDWIISPVDSKESEVRTGLFAIGYYCDKEDMDPFALEEDDGRDVIEDL
>NC_015949.1|WP_041725842.1|2643019_2643847_-|hypothetical-protein
MKNKDYKNKNLIKPAEEQTILDFVEKKLSENAAIRELMKDEYISFSGIRDFLYFKFCPLYFGLCPHKKDKKDEACNANLCWLEKLSDILPSGADNNHQFFHNLVKDTVQPSICPECGEDELELKWQEEGYLAKLGLINFADVAYLECRNCKKRFVTHADRMAVEFLLKVFLAKPSKKSPVKAGQTIVLALDKVGLEIFIDHLEKEKDIKTLWKRLDPFSISDQIGELDLNIAVADFMCEYYNIEYEEKNEVDTFFEEEDTEKFDISDLFDDFDEK
>NC_015949.1|WP_014043427.1|2643926_2644394_-|hypothetical-protein
MLHKFKCMFEDVDIGIFSQMSPVFEIFIDRIVQTLKSMNLNVQKDIVDDIIIEIKEFKVHYAHSSKDVTEALSELILLSQREFLECKIKCNVFLKSKIGTSLTARNVEVLYSPIEEEKDETAKLLRDYLLDIQPLKNMAEKDVGFVKKAIETIFE
>NC_015949.1|WP_014043428.1|2644463_2645162_-|hypothetical-protein
MFKGVSSILTFSEFLNTVIQENKWIYTHELLEKIKVPLPSQNQLKSFEVANSFYKEFLHVVYAVDILSMLNSLKIWAANNNLEIFALLTTDMIPIVWLGEGYYGIIAKYKEKMIIPCALYQHFEDLYINFPMSDFVPFDICDAYRKLMENEENVAMNIVYARSIDELKREFKKNFKEFEIIFKGPDYYDLYVSPVGKKYIVAPLREILKDFFQNQIIYFSQLLSVQENLNKK
>NC_015949.1|WP_013404418.1|2645355_2645616_+|stage-V-sporulation-protein-S
MEVLKVAATSMPQKVANALAAIVKEQGEAELQAVGASAVNQAVKAIAIARGKVAPNGIDLYVIPAFADIVIDGEKKTAIKFIVKSR
>NC_015949.1|WP_013433740.1|2645718_2646114_-|hypothetical-protein
MGFIALEVKELVDILLKNVDMPEIITKVEVNKNEVVVGVKPAAFLPQMSLKFTITSMQNKLSILFDPSKNLIVYGFLLGKLKDEKIEGLQLFKDRLEIDLQKILAGNVKGVKVNRVEVDSGGKIEIDFCCG
>NC_015949.1|WP_014043429.1|2646277_2649328_-|EAL-domain-containing-protein
MKRIRMLVNTVLAVIIIFFLSPAYAGHTPVKFEVDKSYPPFSYTSGGRIYGFTIDLANLVFEPDKFKLALSSDTWNQVYKKLVEGKIDVAAPVAIVEERKKEVYFSKPIFTRHVGLYTSKEFSKNITLKNLEDFKVGVMQSDYTETLLKEKLGVNRYYTYPTIEDLIYALVDGKIDAALMSQEIANYFLVKNGLRDRAELKIKNIFTVKSAFAVSKKRPELVAYINQRLNFLTNKGIFDELYYNYFSTYSPEYYERKNRQIVISSLYLLLIILFAASVAIFVMTRINRRLEHGKQAYEKYAQLLAENANAIVLTLNLNGEIIYFNKFAQELTGYKSEEVVGKKWVDIFIPPHRREYIENLFKRIAEEKILNNHENEIVTKDGDIKWILWNNTLIESPYLNEPMIISTGLDITQIKTTQQLLQQSYKKIERTNQELLNTLEILNRQSKALEEEKEKYKFLIENGSDCIWEIDFKEKNIEFYGRLKDLFDIKAVKSKNDFSAWLDFFHPDDRSTVFKKLQDAILLHEENLEFEARIRDKNGNWHWMSAHVQIFYNEEGKPEKIIAVNIDWTAKKEYEQKIEYIAYYDALTSLPNRKLFEEVLEDFIKKAEEEKAQGAVILIDIDNFKDINDLYGHEAGDEYLKAVCQKVLEYLKSLNLNTFFARVGGDEFAVVLHGLAKKEEVIEVCTHLLNIFESEIYIEKLERDLFASASMGISFYPDDGRSVKEIFRNVDMALSSAKENGKNDFQIFLPFMLTKNLKKIEIEKGLKKAIETDQFELYYQPVINLKDMEIHSVEALLRWISPEKGMISPLEFIPVAEESGLIVKIGEMVIEKAFSDLKEWEKKGIDYLHMAINLSARQFKTKFFENMVQKLIERYSIDPKKISFEITETGAVENFDVSLKILSFLCQMGIKFLIDDFGTGYSSLIYLKRLPIGGVKIDRSFISELEVSKENKAIVEGIILMAHKIDLKVVAEGVETKRQLEILKEVGCDLAQGYLFSKPLPKAEVEKLLIARKITV
>NC_015949.1|WP_014043430.1|2649401_2650409_-|WYL-domain-containing-protein
MEIFLEAKSTFYKALEEIINNAYEKGTISQKEIYDILTRYNCNFPVIEDKLFAKNAQYQKNIYVLKQQDNKTYSLRIDSKIEPYVTNLEIMWLKFIMSSRYAELFLDKNTIEKIKKLKSSYVPSIDTNLIVPKNYSKILKRESAKDLSPKLKMITKSILEKRLLRYTYTTRQGETLKDVVGIPVKIQYSLKDDMFYVIFYSIEHRNFAKCIIQNLEDVRYEEGSFNREDVLKEYELYLRNAKAKQPIIIEVMNTRNALERAFCLFSSFEKSARFLKEKNKHEMKIYYYEFEEAEIISRILYLGKDVVVTQPQHIRESIISRVKNALKMYCDKEIV
>NC_015949.1|WP_014043431.1|2650392_2651706_-|WYL-domain-containing-protein
MPPFNPFVNDFNKLRNFSRIVYLYGCYSREDAENFNIAKRTFDDELRRMRIFLGEEKYLIDEKDGKRKLPCIVEDFFKDVENPLVNIYFSKTSTALQTTLFFMTLQVLNAEHDKKASAGQILDKISQVLDRDVADADLESSLKRILKQMQQLGIIKYLKDEKVYLLCSQAKEVFKDFSIDEIKNIYISVLFFINSHVPSVPGWYLKESLEKYLLELGEKEFIENASSMFWFTYVPHHYILEEELVWKFLEAASNNKKLKVWYWLRKKNKKTEFVCLPVRIVYDVKLGRWYFLVAKEEEVLALPAWRVEKIEILQESFNPKQILPLANLIEKCFFVSVPKRKKGFEKITIRFKNPSNSSYNFVLARVKRELKNARINRVDEETFEVEYELSNIKEFKGWLRSFCERALVLSTTEASRKLREEMINEWKEILKNYGDIS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	MN694574	Marine virus AFVG_250M706, complete genome	30842-30875	5	0.853
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_MF497782	Morganella morganii strain Mmo-37590cz plasmid pMMO-37590cz, complete sequence	3891-3927	5	0.865
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_MG558000	Citrobacter freundii strain Cfr-33795cz plasmid pCfr-33795cz, complete sequence	3891-3927	5	0.865
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NC_013502	Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence	94609-94642	6	0.824
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP028335	Lactobacillus plantarum strain SRCM101167 plasmid unnamed1, complete sequence	24711-24744	6	0.824
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP025416	Lactobacillus plantarum strain X7021 plasmid unnamed4, complete sequence	59830-59863	6	0.824
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	CP020973	Xanthomonas axonopodis pv. phaseoli strain CFBP6546R plasmid pC, complete sequence	68707-68743	6	0.838
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_AP019775	Helicobacter suis strain SNTW101c plasmid pSNTW101c_1, complete sequence	8684-8719	6	0.833
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	AP023044	Helicobacter suis NHP19-4004 plasmid pNHP194004_2 DNA, complete genome	10468-10503	6	0.833
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	AP023040	Helicobacter suis NHP19-4003 plasmid pNHP194003_1 DNA, complete genome	16872-16907	6	0.833
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NZ_CP031409	Borreliella burgdorferi strain MM1 plasmid plsm_lp28-8, complete sequence	27285-27318	7	0.794
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP021007	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6975 plasmid pC, complete sequence	21575-21611	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP020994	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP4885 plasmid pC, complete sequence	26287-26323	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP020969	Xanthomonas phaseoli pv. phaseoli strain CFBP6164 plasmid pC, complete sequence	2390-2426	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP020969	Xanthomonas phaseoli pv. phaseoli strain CFBP6164 plasmid pC, complete sequence	50501-50537	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP021020	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6167 plasmid pC, complete sequence	19401-19437	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP021020	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6167 plasmid pC, complete sequence	24329-24365	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP046571	Xanthomonas albilineans strain Xa-FJ1 plasmid pXaFJ1, complete sequence	8378-8414	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP012062	Xanthomonas sp. ISO98C4 plasmid pNX47, complete sequence	833-869	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP020977	Xanthomonas phaseoli pv. phaseoli strain CFBP6982 plasmid pC	37904-37940	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP012056	Xanthomonas citri pv. fuscans strain ISO12C3 plasmid pXff45, complete sequence	833-869	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP012054	Xanthomonas citri pv. fuscans strain ISO118C1 plasmid pXff45, complete sequence	833-869	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP021003	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6166 plasmid pC, complete sequence	10611-10647	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP012052	Xanthomonas citri pv. fuscans strain ISO118C5 plasmid pXff45, complete sequence	833-869	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	CP021014	Xanthomonas citri pv. phaseoli var. fuscans strain CFBP7767 plasmid pC, complete sequence	40799-40835	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP012059	Xanthomonas phaseoli pv. phaseoli strain ISO98C12 plasmid pXap47, complete sequence	833-869	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP012065	Xanthomonas phaseoli pv. phaseoli strain ISO18C8 plasmid pXap48, complete sequence	833-869	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP012050	Xanthomonas phaseoli pv. phaseoli strain ISO18C2 plasmid pXap48, complete sequence	833-869	7	0.811
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NC_022542	Xanthomonas citri pv. fuscans plasmid plc, complete sequence	833-869	7	0.811
NC_015949_3	3.22\|2565825\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2565825-2565860	36	NZ_CP025893	Escherichia coli strain 503025 plasmid p503025_105, complete sequence	11732-11767	8	0.778
NC_015949_3	3.22\|2565825\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2565825-2565860	36	NZ_CP025893	Escherichia coli strain 503025 plasmid p503025_105, complete sequence	91825-91860	8	0.778
NC_015949_3	3.22\|2565825\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2565825-2565860	36	NZ_CP025866	Escherichia coli strain 504211 plasmid p504211_78, complete sequence	77646-77681	8	0.778
NC_015949_3	3.22\|2565825\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2565825-2565860	36	NZ_CP006002	Escherichia coli B7A plasmid pEB4, complete sequence	7001-7036	8	0.778
NC_015949_3	3.22\|2565825\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2565825-2565860	36	NZ_CP025884	Escherichia coli strain 503440 plasmid p503440_78, complete sequence	66883-66918	8	0.778
NC_015949_3	3.22\|2565825\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2565825-2565860	36	NZ_CP025872	Escherichia coli strain 503829 plasmid p503829_77, complete sequence	29322-29357	8	0.778
NC_015949_3	3.22\|2565825\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2565825-2565860	36	NZ_CP025914	Escherichia coli strain 203740 plasmid p203740_80, complete sequence	3835-3870	8	0.778
NC_015949_3	3.22\|2565825\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2565825-2565860	36	CP025899	Escherichia coli strain 500465 plasmid p500465_77, complete sequence	4393-4428	8	0.778
NC_015949_3	3.22\|2565825\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2565825-2565860	36	LN908839	Escherichia coli plasmid pCss_E1189	31218-31253	8	0.778
NC_015949_4	4.24\|2570803\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2570803-2570836	34	NZ_AP014640	Leptolyngbya boryana IAM M-101 plasmid pLBX	478926-478959	8	0.765
NC_015949_4	4.24\|2570803\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2570803-2570836	34	NZ_AP018205	Leptolyngbya boryana NIES-2135 plasmid plasmid2 DNA, complete genome	26467-26500	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NC_018516	Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence	317235-317268	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP009334	Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence	251431-251464	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP053970	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence	113210-113243	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP053979	Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence	21422-21455	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP013277	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence	239744-239777	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP039723	Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence	7145-7178	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP009348	Bacillus thuringiensis HD1002 plasmid 2, complete sequence	239745-239778	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP045024	Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence	239357-239390	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP013709	Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence	168972-169005	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP013682	Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence	170938-170971	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP013295	Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence	181654-181687	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_MK413720	Enterobacter cloacae strain 12949 plasmid p12949-HI2, complete sequence	220775-220808	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP013844	Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence	214546-214579	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_MG288680	Klebsiella pneumoniae strain D610 plasmid pD610-HI2, complete sequence	209716-209749	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_MF344582	Citrobacter freundii strain 525011 plasmid p525011-HI2, complete sequence	270118-270151	8	0.765
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	MG945746	UNVERIFIED: Microviridae sp. isolate 2702-1801, complete genome	1141-1174	8	0.765
NC_015949_8	8.18\|2598413\|37\|NC_015949\|CRISPRCasFinder,CRT	2598413-2598449	37	NC_007103	Bacillus cereus E33L plasmid pE33L466, complete sequence	150281-150317	8	0.784
NC_015949_8	8.18\|2598413\|37\|NC_015949\|CRISPRCasFinder,CRT	2598413-2598449	37	NZ_CP009967	Bacillus cereus E33L plasmid pBCO_1, complete sequence	171886-171922	8	0.784
NC_015949_9	9.56\|2615931\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2615931-2615966	36	MH616899	Microviridae sp. isolate ctbf550, complete genome	2171-2206	8	0.778
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP018733	Xanthomonas gardneri strain ICMP 7383 plasmid pICMP7383.2, complete sequence	36388-36424	8	0.784
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP018733	Xanthomonas gardneri strain ICMP 7383 plasmid pICMP7383.2, complete sequence	43002-43038	8	0.784
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP016879	Xanthomonas hortorum strain B07-007 plasmid pB07007, complete sequence	30027-30063	8	0.784
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP016879	Xanthomonas hortorum strain B07-007 plasmid pB07007, complete sequence	36641-36677	8	0.784
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NC_008771	Verminephrobacter eiseniae EF01-2 plasmid pVEIS01, complete sequence	19191-19227	8	0.784
NC_015949_1	1.18\|1696872\|34\|NC_015949\|CRISPRCasFinder,CRT	1696872-1696905	34	NZ_CP009417	Jeotgalibacillus malaysiensis strain malaysiensis plasmid unnamed, complete sequence	393412-393445	9	0.735
NC_015949_1	1.18\|1696872\|34\|NC_015949\|CRISPRCasFinder,CRT	1696872-1696905	34	NZ_CP009417	Jeotgalibacillus malaysiensis strain malaysiensis plasmid unnamed, complete sequence	393412-393445	9	0.735
NC_015949_1	1.29\|1697664\|37\|NC_015949\|CRISPRCasFinder,CRT	1697664-1697700	37	NZ_LS992155	Chlamydia sp. S15-834C isolate S15-834K plasmid II, complete sequence	2926-2962	9	0.757
NC_015949_1	1.69\|1697665\|37\|NC_015949\|PILER-CR	1697665-1697701	37	NZ_LS992155	Chlamydia sp. S15-834C isolate S15-834K plasmid II, complete sequence	2926-2962	9	0.757
NC_015949_3	3.16\|2565431\|35\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2565431-2565465	35	NZ_CP032172	Klebsiella pneumoniae strain AR_0076 plasmid unnamed5, complete sequence	5076-5110	9	0.743
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	MN693267	Marine virus AFVG_25M289, complete genome	37428-37461	9	0.735
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NZ_CP012139	Shigella flexneri 2a strain 981 plasmid 981p2, complete sequence	84778-84811	9	0.735
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NZ_AP014804	Escherichia coli O119:H6 strain EC404/03 plasmid pEC404/03-1, complete sequence	20500-20533	9	0.735
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NZ_CP018028	Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence	288978-289011	9	0.735
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NZ_CP018025	Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence	289119-289152	9	0.735
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	MN692994	Marine virus AFVG_117M61, complete genome	34350-34383	9	0.735
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NZ_LR214943	Mycoplasma orale strain NCTC10112 plasmid 4	7732-7765	9	0.735
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NC_018952	Staphylococcus aureus plasmid pWBG747, complete sequence	126-159	9	0.735
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_CP014063	Staphylococcus aureus strain FDAARGOS_159 plasmid unnamed, complete sequence	13736-13769	9	0.735
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NC_013326	Staphylococcus aureus plasmid pWBG746, complete sequence	14973-15006	9	0.735
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	NZ_MK275621	Clostridium perfringens strain JXJA17 plasmid p3, complete sequence	30466-30499	9	0.735
NC_015949_5	5.12\|2574319\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574319-2574352	34	NZ_CP053818	Vibrio cholerae strain SA7G plasmid pSA7G1, complete sequence	52872-52905	9	0.735
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NZ_KY000025	Agrobacterium genomosp. 6 strain AR125 plasmid pTi_AR125, complete sequence	12005-12041	9	0.757
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NZ_KY000029	Agrobacterium genomosp. 6 strain CFBP5499 plasmid pTi_CFBP5499, complete sequence	12005-12041	9	0.757
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NZ_CP039902	Agrobacterium tumefaciens strain CFBP5877 plasmid pTiCFBP5877, complete sequence	9007-9043	9	0.757
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NZ_CP039893	Agrobacterium tumefaciens strain CFBP5499 plasmid pTiCFBP5499, complete sequence	193831-193867	9	0.757
NC_015949_9	9.12\|2612980\|35\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612980-2613014	35	HG796260	Uncultured bacterium plasmid pRGI00100	5951-5985	9	0.743
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NC_017073	Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC3, complete sequence	41790-41825	9	0.75
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	MT375529	Pelagibacter phage Kolga EXVC01, complete genome	37670-37705	9	0.75
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	MT375519	Pelagibacter phage Aegir EXVC01, complete genome	4133-4168	9	0.75
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	MK373781	Escherichia phage vB_EcoM_KAW1E185, complete genome	67016-67051	9	0.75
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	KX229736	Campylobacter phage PC5, complete genome	97407-97442	9	0.75
NC_015949_2	2.3\|2552567\|35\|NC_015949\|CRISPRCasFinder,CRT	2552567-2552601	35	NZ_CP037748	Campylobacter helveticus strain 2013D-9613 plasmid unnamed2, complete sequence	29633-29667	10	0.714
NC_015949_2	2.6\|2552765\|34\|NC_015949\|CRISPRCasFinder,CRT,PILER-CR	2552765-2552798	34	MN694079	Marine virus AFVG_250M40, complete genome	22066-22099	10	0.706
NC_015949_2	2.6\|2552765\|34\|NC_015949\|CRISPRCasFinder,CRT,PILER-CR	2552765-2552798	34	MK448902	Streptococcus phage Javan308, complete genome	29271-29304	10	0.706
NC_015949_4	4.6\|2569618\|35\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2569618-2569652	35	MN856019	Bacteriophage sp. isolate 127, complete genome	11829-11863	10	0.714
NC_015949_4	4.6\|2569618\|35\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2569618-2569652	35	MH622943	Myoviridae sp. isolate ctbc_4, complete genome	102864-102898	10	0.714
NC_015949_4	4.13\|2570078\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2570078-2570111	34	MH538193	Bacillus phage Saddex, complete genome	133251-133284	10	0.706
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NC_005707	Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequence	130096-130129	10	0.706
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	MN693355	Marine virus AFVG_25M40, complete genome	35109-35142	10	0.706
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NZ_CP053290	Bacillus cereus strain WPySW2 plasmid unnamed, complete sequence	35327-35360	10	0.706
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NC_011655	Bacillus cereus AH187 plasmid pAH187_270, complete sequence	206181-206214	10	0.706
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NC_010924	Bacillus cereus strain AH187 plasmid pCER270, complete sequence	262590-262623	10	0.706
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	CP045776	Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence	255015-255048	10	0.706
NC_015949_5	5.5\|2573854\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2573854-2573887	34	NC_016792	Bacillus cereus NC7401 plasmid pNCcld, complete sequence	261459-261492	10	0.706
NC_015949_5	5.8\|2574053\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574053-2574086	34	MN693267	Marine virus AFVG_25M289, complete genome	37428-37461	10	0.706
NC_015949_9	9.15\|2613180\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2613180-2613216	37	AP018319	Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome	409004-409040	10	0.73
NC_015949_9	9.16\|2613247\|35\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2613247-2613281	35	MN694454	Marine virus AFVG_250M626, complete genome	85-119	10	0.714
NC_015949_9	9.27\|2613985\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2613985-2614020	36	NZ_AP017296	Nostoc sp. NIES-3756 plasmid pNOS3756_1, complete sequence	33398-33433	10	0.722
NC_015949_12	12.3\|2638861\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638861-2638896	36	NZ_CP007648	Lactobacillus salivarius strain JCM1046 plasmid pMP1046B, complete sequence	31153-31188	10	0.722
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP046571	Xanthomonas albilineans strain Xa-FJ1 plasmid pXaFJ1, complete sequence	3892-3928	10	0.73
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_CP041049	Citrobacter sp. CF971 plasmid pBM527-3, complete sequence	15377-15413	10	0.73
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_KX863568	Citrobacter freundii strain AtetA plasmid pLNU-11, complete sequence	1821-1857	10	0.73
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	LC486677	Serratia marcescens MRY16-414SMA plasmid pMRY16-414SMA_2 DNA, complete sequence	6225-6261	10	0.73
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	MN436715	Klebsiella pneumoniae strain NMI4661/17 plasmid pKRA-GES-5, complete sequence	17182-17218	10	0.73
NC_015949_12	12.4\|2638927\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2638927-2638963	37	NZ_LS998784	Pseudomonas aeruginosa isolate 1 plasmid 2, complete sequence	1175-1211	10	0.73
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	MK448990	Streptococcus phage Javan584, complete genome	18779-18814	10	0.722
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	MK448812	Streptococcus phage Javan577, complete genome	16444-16479	10	0.722
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	MK448806	Streptococcus phage Javan565, complete genome	16729-16764	10	0.722
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_LN999836	Candidatus Hoaglandella endobia isolate HETPER plasmid II, complete sequence	2864-2899	10	0.722
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP013238	Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence	15705-15740	10	0.722
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	MG867727	Escherichia phage vB_EcoM-G28, complete genome	69424-69459	10	0.722
NC_015949_2	2.32\|2554478\|37\|NC_015949\|CRISPRCasFinder,CRT,PILER-CR	2554478-2554514	37	NZ_LR134418	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 9	17425-17461	11	0.703
NC_015949_4	4.6\|2569618\|35\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2569618-2569652	35	NZ_AP019839	Leptotrichia wadei strain JMUB3934 plasmid pJMUB3934p4, complete sequence	932-966	11	0.686
NC_015949_5	5.12\|2574319\|34\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2574319-2574352	34	CP027480	Pseudomonas koreensis strain P19E3 plasmid p3, complete sequence	242364-242397	11	0.676
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NZ_CP036488	Rahnella aquatilis strain MEM40 plasmid pMEM40-1, complete sequence	265707-265743	11	0.703
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NC_017060	Rahnella aquatilis HX2 plasmid PRA1, complete sequence	338125-338161	11	0.703
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NC_015062	Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequence	340947-340983	11	0.703
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NZ_CP034838	Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence	327702-327738	11	0.703
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NZ_CP034839	Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence	327702-327738	11	0.703
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NZ_CP034837	Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence	293378-293414	11	0.703
NC_015949_9	9.6\|2612581\|37\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2612581-2612617	37	NZ_CP032297	Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence	301567-301603	11	0.703
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	MN692968	Marine virus AFVG_117M26, complete genome	37568-37603	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	MN694254	Marine virus AFVG_250M1006, complete genome	37598-37633	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP024317	Borrelia miyamotoi strain Yekat-6 plasmid pYkt6-lp72, complete sequence	7760-7795	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP024391	Borrelia miyamotoi strain Izh-4 plasmid pIzh4-lp72, complete sequence	65755-65790	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP010187	Escherichia coli strain M6 plasmid A, complete genome	17091-17126	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP010207	Escherichia coli strain M11 plasmid A, complete sequence	111066-111101	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP010197	Escherichia coli strain M9 plasmid A, complete genome	17091-17126	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP024206	Borrelia miyamotoi strain Izh-5 plasmid pIzh5-lp72, complete sequence	7766-7801	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP024334	Borrelia miyamotoi strain Yekat-1 plasmid pYkt1-lp72, complete sequence	64614-64649	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP010222	Escherichia coli strain M19 plasmid A, complete sequence	17091-17126	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP024352	Borrelia miyamotoi strain Izh-16 plasmid pIzh16-lp72, complete sequence	7776-7811	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP010214	Escherichia coli strain M15 plasmid A, complete sequence	117537-117572	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_AP017969	Fusobacterium varium strain Fv113-g1 plasmid pFV113-g1-1, complete sequence	25704-25739	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP024372	Borrelia miyamotoi strain Izh-14 plasmid pIzh14-lp72, complete sequence	7754-7789	11	0.694
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NC_022551	Blattabacterium sp. (Nauphoeta cinerea) plasmid unnamed, complete sequence	2027-2062	14	0.611
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NC_013419	Blattabacterium sp. (Periplaneta americana) str. BPLAN plasmid pBPLAN, complete sequence	1858-1893	14	0.611
NC_015949_12	12.13\|2639526\|36\|NC_015949\|PILER-CR,CRISPRCasFinder,CRT	2639526-2639561	36	NZ_CP017256	Clostridium taeniosporum strain 1/k plasmid pCt3, complete sequence	44329-44364	14	0.611

1. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MN694574 (Marine virus AFVG_250M706, complete genome) position: , mismatch: 5, identity: 0.853

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
ttctttaaatctttttttgtttttacaaattttc	Protospacer
*..*********************** * ****

2. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF497782 (Morganella morganii strain Mmo-37590cz plasmid pMMO-37590cz, complete sequence) position: , mismatch: 5, identity: 0.865

agagctttcgcggcataaacggtttcccccccgcaag-	CRISPR spacer
gcgactttcgcggcataaacggttt-ccccccgcaagc	Protospacer
. ..********************* ***********

3. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG558000 (Citrobacter freundii strain Cfr-33795cz plasmid pCfr-33795cz, complete sequence) position: , mismatch: 5, identity: 0.865

agagctttcgcggcataaacggtttcccccccgcaag-	CRISPR spacer
gcgactttcgcggcataaacggttt-ccccccgcaagc	Protospacer
. ..********************* ***********

4. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_013502 (Rhodothermus marinus DSM 4252 plasmid pRMAR01, complete sequence) position: , mismatch: 6, identity: 0.824

tcttttaaatctttttttgttttt---accattttta	CRISPR spacer
tcttttaactctatttttgttttttcatccattt---	Protospacer
******** *** ***********    ******

5. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028335 (Lactobacillus plantarum strain SRCM101167 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.824

tcttttaaatcttttttttctct----tctcgttttta	CRISPR spacer
tcttttaattctttttgttctcttttatctcgtt----	Protospacer
******** ******* ******    *******

6. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025416 (Lactobacillus plantarum strain X7021 plasmid unnamed4, complete sequence) position: , mismatch: 6, identity: 0.824

tcttttaaatcttttttttctct----tctcgttttta	CRISPR spacer
tcttttaattctttttgttctcttttatctcgtt----	Protospacer
******** ******* ******    *******

7. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to CP020973 (Xanthomonas axonopodis pv. phaseoli strain CFBP6546R plasmid pC, complete sequence) position: , mismatch: 6, identity: 0.838

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
agggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
**.*********************.***** *.**.

8. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019775 (Helicobacter suis strain SNTW101c plasmid pSNTW101c_1, complete sequence) position: , mismatch: 6, identity: 0.833

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
ggcaaatcttaaaaaaattttaaaattttttttctt	Protospacer
.**   *.***************** **********

9. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to AP023044 (Helicobacter suis NHP19-4004 plasmid pNHP194004_2 DNA, complete genome) position: , mismatch: 6, identity: 0.833

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
ggcaaatcttaaaaaaattttaaaattttttttctt	Protospacer
.**   *.***************** **********

10. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to AP023040 (Helicobacter suis NHP19-4003 plasmid pNHP194003_1 DNA, complete genome) position: , mismatch: 6, identity: 0.833

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
ggcaaatcttaaaaaaattttaaaattttttttctt	Protospacer
.**   *.***************** **********

11. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031409 (Borreliella burgdorferi strain MM1 plasmid plsm_lp28-8, complete sequence) position: , mismatch: 7, identity: 0.794

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
tttttattagctttttttgtttttaccaattgta	Protospacer
*.***   * ****************** ** **

12. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021007 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6975 plasmid pC, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

13. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020994 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP4885 plasmid pC, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

14. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020969 (Xanthomonas phaseoli pv. phaseoli strain CFBP6164 plasmid pC, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

15. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020969 (Xanthomonas phaseoli pv. phaseoli strain CFBP6164 plasmid pC, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

16. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021020 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6167 plasmid pC, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

17. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021020 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6167 plasmid pC, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

18. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046571 (Xanthomonas albilineans strain Xa-FJ1 plasmid pXaFJ1, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

19. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012062 (Xanthomonas sp. ISO98C4 plasmid pNX47, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

20. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020977 (Xanthomonas phaseoli pv. phaseoli strain CFBP6982 plasmid pC) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

21. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012056 (Xanthomonas citri pv. fuscans strain ISO12C3 plasmid pXff45, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

22. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012054 (Xanthomonas citri pv. fuscans strain ISO118C1 plasmid pXff45, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

23. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021003 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP6166 plasmid pC, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

24. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012052 (Xanthomonas citri pv. fuscans strain ISO118C5 plasmid pXff45, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

25. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to CP021014 (Xanthomonas citri pv. phaseoli var. fuscans strain CFBP7767 plasmid pC, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

26. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012059 (Xanthomonas phaseoli pv. phaseoli strain ISO98C12 plasmid pXap47, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

27. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012065 (Xanthomonas phaseoli pv. phaseoli strain ISO18C8 plasmid pXap48, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

28. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012050 (Xanthomonas phaseoli pv. phaseoli strain ISO18C2 plasmid pXap48, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

29. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_022542 (Xanthomonas citri pv. fuscans plasmid plc, complete sequence) position: , mismatch: 7, identity: 0.811

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
ggggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
.*.*********************.***** *.**.

30. spacer 3.22|2565825|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025893 (Escherichia coli strain 503025 plasmid p503025_105, complete sequence) position: , mismatch: 8, identity: 0.778

taggcatggatgatttgtttgagaaaa--ttgaaagta	CRISPR spacer
aaggcatggatgatttttttgacaaaaacttcacac--	Protospacer
 *************** ***** ****  ** * *

31. spacer 3.22|2565825|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025893 (Escherichia coli strain 503025 plasmid p503025_105, complete sequence) position: , mismatch: 8, identity: 0.778

taggcatggatgatttgtttgagaaaa--ttgaaagta	CRISPR spacer
aaggcatggatgatttttttgacaaaaacttcacac--	Protospacer
 *************** ***** ****  ** * *

32. spacer 3.22|2565825|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025866 (Escherichia coli strain 504211 plasmid p504211_78, complete sequence) position: , mismatch: 8, identity: 0.778

taggcatggatgatttgtttgagaaaa--ttgaaagta	CRISPR spacer
aaggcatggatgatttttttgacaaaaacttcacac--	Protospacer
 *************** ***** ****  ** * *

33. spacer 3.22|2565825|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006002 (Escherichia coli B7A plasmid pEB4, complete sequence) position: , mismatch: 8, identity: 0.778

taggcatggatgatttgtttgagaaaa--ttgaaagta	CRISPR spacer
aaggcatggatgatttttttgacaaaaacttcacac--	Protospacer
 *************** ***** ****  ** * *

34. spacer 3.22|2565825|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025884 (Escherichia coli strain 503440 plasmid p503440_78, complete sequence) position: , mismatch: 8, identity: 0.778

taggcatggatgatttgtttgagaaaa--ttgaaagta	CRISPR spacer
aaggcatggatgatttttttgacaaaaacttcacac--	Protospacer
 *************** ***** ****  ** * *

35. spacer 3.22|2565825|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025872 (Escherichia coli strain 503829 plasmid p503829_77, complete sequence) position: , mismatch: 8, identity: 0.778

taggcatggatgatttgtttgagaaaa--ttgaaagta	CRISPR spacer
aaggcatggatgatttttttgacaaaaacttcacac--	Protospacer
 *************** ***** ****  ** * *

36. spacer 3.22|2565825|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025914 (Escherichia coli strain 203740 plasmid p203740_80, complete sequence) position: , mismatch: 8, identity: 0.778

taggcatggatgatttgtttgagaaaa--ttgaaagta	CRISPR spacer
aaggcatggatgatttttttgacaaaaacttcacac--	Protospacer
 *************** ***** ****  ** * *

37. spacer 3.22|2565825|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to CP025899 (Escherichia coli strain 500465 plasmid p500465_77, complete sequence) position: , mismatch: 8, identity: 0.778

taggcatggatgatttgtttgagaaaa--ttgaaagta	CRISPR spacer
aaggcatggatgatttttttgacaaaaacttcacac--	Protospacer
 *************** ***** ****  ** * *

38. spacer 3.22|2565825|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to LN908839 (Escherichia coli plasmid pCss_E1189) position: , mismatch: 8, identity: 0.778

taggcatggatgatttgtttgagaaaa--ttgaaagta	CRISPR spacer
aaggcatggatgatttttttgacaaaaacttcacac--	Protospacer
 *************** ***** ****  ** * *

39. spacer 4.24|2570803|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014640 (Leptolyngbya boryana IAM M-101 plasmid pLBX) position: , mismatch: 8, identity: 0.765

gccaaacatacaaccatcgccaattcatcaattc	CRISPR spacer
ctcgtacatacaaccttctccaattcatcaatgt	Protospacer
 .*. ********** ** ************* .

40. spacer 4.24|2570803|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018205 (Leptolyngbya boryana NIES-2135 plasmid plasmid2 DNA, complete genome) position: , mismatch: 8, identity: 0.765

gccaaacatacaaccatcgccaattcatcaattc	CRISPR spacer
ctcgtacatacaaccttctccaattcatcaatgt	Protospacer
 .*. ********** ** ************* .

41. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_018516 (Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
aaatctcaatcttttcttcctcttctcgttttga	Protospacer
   *.* ********.**.************* *

42. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009334 (Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
aaatctcaatcttttcttcctcttctcgttttga	Protospacer
   *.* ********.**.************* *

43. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053970 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
aaatctcaatcttttcttcctcttctcgttttga	Protospacer
   *.* ********.**.************* *

44. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053979 (Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
aaatctcaatcttttcttcctcttctcgttttga	Protospacer
   *.* ********.**.************* *

45. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013277 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
aaatctcaatcttttcttcctcttctcgttttga	Protospacer
   *.* ********.**.************* *

46. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039723 (Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
aaatctcaatcttttcttcctcttctcgttttga	Protospacer
   *.* ********.**.************* *

47. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009348 (Bacillus thuringiensis HD1002 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
aaatctcaatcttttcttcctcttctcgttttga	Protospacer
   *.* ********.**.************* *

48. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045024 (Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
aaatctcaatcttttcttcctcttctcgttttga	Protospacer
   *.* ********.**.************* *

49. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013709 (Clostridium botulinum strain F634 plasmid pRSJ2_2, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
tcttttaaatctttattttctattaacatattat	Protospacer
************** ****** **  *.* **

50. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013682 (Clostridium botulinum strain 1169 plasmid pRSJ8_1, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
tcttttaaatctttattttctattaacatattat	Protospacer
************** ****** **  *.* **

51. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013295 (Clostridium botulinum strain CDC_54064 plasmid pNPD1_1, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
tcttttaaatctttattttctattaacatattat	Protospacer
************** ****** **  *.* **

52. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK413720 (Enterobacter cloacae strain 12949 plasmid p12949-HI2, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
tcttttaagtctttttgttctctttcataattta	Protospacer
********.******* *******..    ****

53. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013844 (Clostridium botulinum strain A634 plasmid pRSJ19_2, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
tcttttaaatctttattttctattaacatattat	Protospacer
************** ****** **  *.* **

54. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG288680 (Klebsiella pneumoniae strain D610 plasmid pD610-HI2, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
tcttttaagtctttttgttctctttcataattta	Protospacer
********.******* *******..    ****

55. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF344582 (Citrobacter freundii strain 525011 plasmid p525011-HI2, complete sequence) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
tcttttaagtctttttgttctctttcataattta	Protospacer
********.******* *******..    ****

56. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MG945746 (UNVERIFIED: Microviridae sp. isolate 2702-1801, complete genome) position: , mismatch: 8, identity: 0.765

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
tatttcttttctttgttttctattctcgtttttc	Protospacer
* ***.   ***** ****** ***********

57. spacer 8.18|2598413|37|NC_015949|CRISPRCasFinder,CRT matches to NC_007103 (Bacillus cereus E33L plasmid pE33L466, complete sequence) position: , mismatch: 8, identity: 0.784

aatcctcctccttttctgttttttcaaaagccttcac--	CRISPR spacer
aatcctcctctttttctgctttttc--aatttttcatcc	Protospacer
**********.*******.******  ** ..****.

58. spacer 8.18|2598413|37|NC_015949|CRISPRCasFinder,CRT matches to NZ_CP009967 (Bacillus cereus E33L plasmid pBCO_1, complete sequence) position: , mismatch: 8, identity: 0.784

aatcctcctccttttctgttttttcaaaagccttcac--	CRISPR spacer
aatcctcctctttttctgctttttc--aatttttcatcc	Protospacer
**********.*******.******  ** ..****.

59. spacer 9.56|2615931|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MH616899 (Microviridae sp. isolate ctbf550, complete genome) position: , mismatch: 8, identity: 0.778

gcttgttagaatatcagcaaacaagagcaaa--aatca	CRISPR spacer
aactattagaatatcatcaaaaaagagcaaaccaat--	Protospacer
. .*.*********** **** *********  ***

60. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018733 (Xanthomonas gardneri strain ICMP 7383 plasmid pICMP7383.2, complete sequence) position: , mismatch: 8, identity: 0.784

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
gcggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
. .*********************.***** *.**.

61. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018733 (Xanthomonas gardneri strain ICMP 7383 plasmid pICMP7383.2, complete sequence) position: , mismatch: 8, identity: 0.784

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
gcggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
. .*********************.***** *.**.

62. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016879 (Xanthomonas hortorum strain B07-007 plasmid pB07007, complete sequence) position: , mismatch: 8, identity: 0.784

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
gcggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
. .*********************.***** *.**.

63. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016879 (Xanthomonas hortorum strain B07-007 plasmid pB07007, complete sequence) position: , mismatch: 8, identity: 0.784

agagctttcgcggcataaacggtttccccc-ccgcaag	CRISPR spacer
gcggctttcgcggcataaacggttccccccgctgcgc-	Protospacer
. .*********************.***** *.**.

64. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_008771 (Verminephrobacter eiseniae EF01-2 plasmid pVEIS01, complete sequence) position: , mismatch: 8, identity: 0.784

agagctttcgcggcataaacggtttcccccccgcaag-	CRISPR spacer
cggactttcgcggcataaacgg-ttcccccctacgggc	Protospacer
 *..****************** ********..*..*

65. spacer 1.18|1696872|34|NC_015949|CRISPRCasFinder,CRT matches to NZ_CP009417 (Jeotgalibacillus malaysiensis strain malaysiensis plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

tttatagaggagtagacacctactcctctgtagc	CRISPR spacer
agaaaagaggagtagatatctactcctctttttc	Protospacer
   * ***********.*.********** *  *

66. spacer 1.18|1696872|34|NC_015949|CRISPRCasFinder,CRT matches to NZ_CP009417 (Jeotgalibacillus malaysiensis strain malaysiensis plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

tttatagaggagtagacacctactcctctgtagc	CRISPR spacer
agaaaagaggagtagatatctactcctctttttc	Protospacer
   * ***********.*.********** *  *

67. spacer 1.29|1697664|37|NC_015949|CRISPRCasFinder,CRT matches to NZ_LS992155 (Chlamydia sp. S15-834C isolate S15-834K plasmid II, complete sequence) position: , mismatch: 9, identity: 0.757

ttccccatagctggtcttgcagcaataatgtataagc	CRISPR spacer
ttccccatagcaggtcttgcagcaacaacaacaaaat	Protospacer
*********** *************.**..   **..

68. spacer 1.69|1697665|37|NC_015949|PILER-CR matches to NZ_LS992155 (Chlamydia sp. S15-834C isolate S15-834K plasmid II, complete sequence) position: , mismatch: 9, identity: 0.757

ttccccatagctggtcttgcagcaataatgtataagc	CRISPR spacer
ttccccatagcaggtcttgcagcaacaacaacaaaat	Protospacer
*********** *************.**..   **..

69. spacer 3.16|2565431|35|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032172 (Klebsiella pneumoniae strain AR_0076 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.743

ttgtaaccttttgcaacattatttaacgctgtcga	CRISPR spacer
tgttgactttgtgcaacattatttaacgctgcacg	Protospacer
*  *.**.** ********************.  .

70. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MN693267 (Marine virus AFVG_25M289, complete genome) position: , mismatch: 9, identity: 0.735

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
tcttttaaatcttttttttgttttaatttcacca	Protospacer
******************  ***** . *. ..*

71. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012139 (Shigella flexneri 2a strain 981 plasmid 981p2, complete sequence) position: , mismatch: 9, identity: 0.735

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
tacagccattcctgttttgtttttaccattttta	Protospacer
* .  . * **.* ********************

72. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014804 (Escherichia coli O119:H6 strain EC404/03 plasmid pEC404/03-1, complete sequence) position: , mismatch: 9, identity: 0.735

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
tattttaaatatttttttgttgttacccgagtgt	Protospacer
* ******** ********** *****    *

73. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018028 (Alteromonas mediterranea strain CP49 plasmid MCP49-600, complete sequence) position: , mismatch: 9, identity: 0.735

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
tcttttaaatcttttattgttgttccaagcatgt	Protospacer
*************** ***** ** * * . *

74. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018025 (Alteromonas mediterranea strain CP48 plasmid pAMCP48-600, complete sequence) position: , mismatch: 9, identity: 0.735

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
tcttttaaatcttttattgttgttccaagcatgt	Protospacer
*************** ***** ** * * . *

75. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MN692994 (Marine virus AFVG_117M61, complete genome) position: , mismatch: 9, identity: 0.735

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
ttatttaaatgtttttttgttttttcccatatag	Protospacer
*. ******* ************* **  * * .

76. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214943 (Mycoplasma orale strain NCTC10112 plasmid 4) position: , mismatch: 9, identity: 0.735

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
tcttctaaatcttttttagtttttttatcttctt	Protospacer
****.************ ****** .  .**.*

77. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_018952 (Staphylococcus aureus plasmid pWBG747, complete sequence) position: , mismatch: 9, identity: 0.735

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
acgatttaatcatttttttctcttctcgacctaa	Protospacer
 *  ** **** **************** ..* *

78. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014063 (Staphylococcus aureus strain FDAARGOS_159 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
acgatttaatcatttttttctcttctcgacctaa	Protospacer
 *  ** **** **************** ..* *

79. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_013326 (Staphylococcus aureus plasmid pWBG746, complete sequence) position: , mismatch: 9, identity: 0.735

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
acgatttaatcatttttttctcttctcgacctaa	Protospacer
 *  ** **** **************** ..* *

80. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK275621 (Clostridium perfringens strain JXJA17 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.735

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
tcttttaaatcttctttttcttttaatgcagata	Protospacer
*************.*******.**  .*.   **

81. spacer 5.12|2574319|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053818 (Vibrio cholerae strain SA7G plasmid pSA7G1, complete sequence) position: , mismatch: 9, identity: 0.735

caagattttgcttgcaattggctttaagtgttcc	CRISPR spacer
tgggattttaattgcaattggctttaacgctttc	Protospacer
...******. ****************   **.*

82. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000025 (Agrobacterium genomosp. 6 strain AR125 plasmid pTi_AR125, complete sequence) position: , mismatch: 9, identity: 0.757

atatttacttttgccttttctgtct------cagctttcaaaa	CRISPR spacer
atatttacttttgccttgcctgtctcaccgacagcct------	Protospacer
***************** .******      ****.*

83. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KY000029 (Agrobacterium genomosp. 6 strain CFBP5499 plasmid pTi_CFBP5499, complete sequence) position: , mismatch: 9, identity: 0.757

atatttacttttgccttttctgtct------cagctttcaaaa	CRISPR spacer
atatttacttttgccttgcctgtctcaccgacagcct------	Protospacer
***************** .******      ****.*

84. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039902 (Agrobacterium tumefaciens strain CFBP5877 plasmid pTiCFBP5877, complete sequence) position: , mismatch: 9, identity: 0.757

atatttacttttgccttttctgtct------cagctttcaaaa	CRISPR spacer
atatttacttttgccttgcctgtctcaccgacagcct------	Protospacer
***************** .******      ****.*

85. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039893 (Agrobacterium tumefaciens strain CFBP5499 plasmid pTiCFBP5499, complete sequence) position: , mismatch: 9, identity: 0.757

atatttacttttgccttttctgtct------cagctttcaaaa	CRISPR spacer
atatttacttttgccttgcctgtctcaccgacagcct------	Protospacer
***************** .******      ****.*

86. spacer 9.12|2612980|35|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to HG796260 (Uncultured bacterium plasmid pRGI00100) position: , mismatch: 9, identity: 0.743

tgctcagatagacgaagcagattat-atttgtaagc	CRISPR spacer
aaagcagatagatgaagcagattataatttagcag-	Protospacer
 .  ********.************ ****.  **

87. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_017073 (Selenomonas ruminantium subsp. lactilytica TAM6421 plasmid pSRC3, complete sequence) position: , mismatch: 9, identity: 0.75

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
ccctattttgaaaaaaagtttaaaaattttttcttg	Protospacer
  *. **** ******* **************..*

88. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MT375529 (Pelagibacter phage Kolga EXVC01, complete genome) position: , mismatch: 9, identity: 0.75

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
caccaagattaaaaaaatttaaaaaatttatttctg	Protospacer
 .**    ************ ******** *****

89. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MT375519 (Pelagibacter phage Aegir EXVC01, complete genome) position: , mismatch: 9, identity: 0.75

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
caccaagattaaaaaaatttaaaaaatttatttctg	Protospacer
 .**    ************ ******** *****

90. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MK373781 (Escherichia phage vB_EcoM_KAW1E185, complete genome) position: , mismatch: 9, identity: 0.75

agcccttttt---aaaaaaattttaaaaatttttttctt	CRISPR spacer
---ccgttttgtgaaaaaaattttaaaaatttttaggga	Protospacer
   ** ****   *********************

91. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to KX229736 (Campylobacter phage PC5, complete genome) position: , mismatch: 9, identity: 0.75

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
aaattttttaaaaataattttaaaaatttttgtttg	Protospacer
*. ..**** **** **************** *.*

92. spacer 2.3|2552567|35|NC_015949|CRISPRCasFinder,CRT matches to NZ_CP037748 (Campylobacter helveticus strain 2013D-9613 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.714

aaccctcccattttttatttttttttcaaacccca	CRISPR spacer
ataaacgccattttttattttttttataaacccac	Protospacer
*    . ****************** .******

93. spacer 2.6|2552765|34|NC_015949|CRISPRCasFinder,CRT,PILER-CR matches to MN694079 (Marine virus AFVG_250M40, complete genome) position: , mismatch: 10, identity: 0.706

aaccctcccattttttattttttttcaaacccca	CRISPR spacer
gagccttccattatttattttttttcataaagtt	Protospacer
.* ***.***** ************** *   .

94. spacer 2.6|2552765|34|NC_015949|CRISPRCasFinder,CRT,PILER-CR matches to MK448902 (Streptococcus phage Javan308, complete genome) position: , mismatch: 10, identity: 0.706

aaccctcccattttttattttttttcaaacccca	CRISPR spacer
tctcttccccttttttattttgtttcaaaaacgc	Protospacer
  .*.**** *********** *******  *

95. spacer 4.6|2569618|35|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MN856019 (Bacteriophage sp. isolate 127, complete genome) position: , mismatch: 10, identity: 0.714

actctctctaattactaattaattttttatttttt	CRISPR spacer
gtgagttttaattactaattacttttttctttttc	Protospacer
..   .*.************* ****** *****.

96. spacer 4.6|2569618|35|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MH622943 (Myoviridae sp. isolate ctbc_4, complete genome) position: , mismatch: 10, identity: 0.714

actctctctaattactaattaattttttatttttt	CRISPR spacer
atattaattaattactaattcatattttattttac	Protospacer
*. .*  .************ ** ********* .

97. spacer 4.13|2570078|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MH538193 (Bacillus phage Saddex, complete genome) position: , mismatch: 10, identity: 0.706

aaatcaactaaaactccaatctctctacctcttt	CRISPR spacer
gagctataagaaactccaatctctccaactcttt	Protospacer
.*...*   .***************.* ******

98. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_005707 (Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequence) position: , mismatch: 10, identity: 0.706

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
attaaggattccttttttgtttttaccacttttt	Protospacer
 .*   .* **.****************.****

99. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MN693355 (Marine virus AFVG_25M40, complete genome) position: , mismatch: 10, identity: 0.706

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
tgtaccccctctttttttgtttttactttttttt	Protospacer
* * ..   *****************. *****

100. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053290 (Bacillus cereus strain WPySW2 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
attaaggattccttttttgtttttaccacttttt	Protospacer
 .*   .* **.****************.****

101. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_011655 (Bacillus cereus AH187 plasmid pAH187_270, complete sequence) position: , mismatch: 10, identity: 0.706

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
attaaggattccttttttgtttttaccacttttt	Protospacer
 .*   .* **.****************.****

102. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_010924 (Bacillus cereus strain AH187 plasmid pCER270, complete sequence) position: , mismatch: 10, identity: 0.706

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
attaaggattccttttttgtttttaccacttttt	Protospacer
 .*   .* **.****************.****

103. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to CP045776 (Bacillus paranthracis strain CFSAN068816 plasmid p1CFSAN068816, complete sequence) position: , mismatch: 10, identity: 0.706

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
attaaggattccttttttgtttttaccacttttt	Protospacer
 .*   .* **.****************.****

104. spacer 5.5|2573854|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_016792 (Bacillus cereus NC7401 plasmid pNCcld, complete sequence) position: , mismatch: 10, identity: 0.706

tcttttaaatctttttttgtttttaccattttta	CRISPR spacer
attaaggattccttttttgtttttaccacttttt	Protospacer
 .*   .* **.****************.****

105. spacer 5.8|2574053|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MN693267 (Marine virus AFVG_25M289, complete genome) position: , mismatch: 10, identity: 0.706

tcttttaaatcttttttttctcttctcgttttta	CRISPR spacer
tcttttaaatcttttttttgttttaatttcacca	Protospacer
******************* *.**  . *. ..*

106. spacer 9.15|2613180|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to AP018319 (Nostoc sp. HK-01 plasmid plasmid1 DNA, complete genome) position: , mismatch: 10, identity: 0.73

tgtgattgcaattgctcttgtatctttgattcaatct	CRISPR spacer
tctgcttgcaattgctcttgtatctctgcgacagaaa	Protospacer
* ** ********************.**   **.

107. spacer 9.16|2613247|35|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MN694454 (Marine virus AFVG_250M626, complete genome) position: , mismatch: 10, identity: 0.714

ccaccacgt-----actaatgattgattgatagtacgaat	CRISPR spacer
-----atctgggcagctaatgattgattgataggaagaat	Protospacer
     *. *     .****************** * ****

108. spacer 9.27|2613985|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP017296 (Nostoc sp. NIES-3756 plasmid pNOS3756_1, complete sequence) position: , mismatch: 10, identity: 0.722

aattattgtccaagattttaataattcatattttat	CRISPR spacer
tatatacaaccaaaatttaaataattcatattttaa	Protospacer
 **   .. ****.**** ****************

109. spacer 12.3|2638861|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007648 (Lactobacillus salivarius strain JCM1046 plasmid pMP1046B, complete sequence) position: , mismatch: 10, identity: 0.722

atccattgctcttgttttcttgctttatcaactctg	CRISPR spacer
cttcccattccttgttttcttgctttctcaagtctg	Protospacer
 *.* .  ..**************** **** ****

110. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046571 (Xanthomonas albilineans strain Xa-FJ1 plasmid pXaFJ1, complete sequence) position: , mismatch: 10, identity: 0.73

agagctttcgcggcataaacggtttcccccccgcaag	CRISPR spacer
ggggctttcgcggcataaacggtgccccccgctacgc	Protospacer
.*.******************** .***** *   .

111. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041049 (Citrobacter sp. CF971 plasmid pBM527-3, complete sequence) position: , mismatch: 10, identity: 0.73

agagctttcgcggcataaacggtttcccccccgcaag-	CRISPR spacer
gcgactttcgcggcataaacgg-tgcccccctacgggc	Protospacer
. ..****************** * ******..*..*

112. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KX863568 (Citrobacter freundii strain AtetA plasmid pLNU-11, complete sequence) position: , mismatch: 10, identity: 0.73

agagctttcgcggcataaacggtttcccccccgcaag-	CRISPR spacer
gcgactttcgcggcataaacgg-tgcccccctacgggc	Protospacer
. ..****************** * ******..*..*

113. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to LC486677 (Serratia marcescens MRY16-414SMA plasmid pMRY16-414SMA_2 DNA, complete sequence) position: , mismatch: 10, identity: 0.73

agagctttcgcggcataaacggtttcccccccgcaag-	CRISPR spacer
gcgactttcgcggcataaacgg-tgcccccctacgggc	Protospacer
. ..****************** * ******..*..*

114. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MN436715 (Klebsiella pneumoniae strain NMI4661/17 plasmid pKRA-GES-5, complete sequence) position: , mismatch: 10, identity: 0.73

agagctttcgcggcataaacggtttcccccccgcaag-	CRISPR spacer
gcgactttcgcggcataaacgg-tgcccccctacgggc	Protospacer
. ..****************** * ******..*..*

115. spacer 12.4|2638927|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LS998784 (Pseudomonas aeruginosa isolate 1 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.73

agagctttcgcggcataaacggtttcccccccgcaag-	CRISPR spacer
gcgactttcgcggcataaacgg-tgcccccctacgggc	Protospacer
. ..****************** * ******..*..*

116. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MK448990 (Streptococcus phage Javan584, complete genome) position: , mismatch: 10, identity: 0.722

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
gcatttttataaaaaaattttaaaaattttttcgaa	Protospacer
.  ..*** ***********************.

117. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MK448812 (Streptococcus phage Javan577, complete genome) position: , mismatch: 10, identity: 0.722

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
gcatttttataaaaaaattttaaaaattttttcgaa	Protospacer
.  ..*** ***********************.

118. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MK448806 (Streptococcus phage Javan565, complete genome) position: , mismatch: 10, identity: 0.722

agccctttttaaaaaaattttaaaaatttttttctt-	CRISPR spacer
-gtgtttttataaaaaaatttaaaaaattttttcgaa	Protospacer
 *. .****  ****** ******** *******

119. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN999836 (Candidatus Hoaglandella endobia isolate HETPER plasmid II, complete sequence) position: , mismatch: 10, identity: 0.722

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
gcttggttacaaaaaaattctaaaaatttttctctt	Protospacer
. ..  ** .*********.***********.****

120. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013238 (Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence) position: , mismatch: 10, identity: 0.722

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
aaaattttttataaaaattataaaaatttttcttaa	Protospacer
*.  .****** ******* ***********.*.

121. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MG867727 (Escherichia phage vB_EcoM-G28, complete genome) position: , mismatch: 10, identity: 0.722

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
accgttttgtgaaaaaattttaaaaatttttaggga	Protospacer
* * .*** *.********************

122. spacer 2.32|2554478|37|NC_015949|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR134418 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 9) position: , mismatch: 11, identity: 0.703

cataaattcgtttacttcttctatttcgtaatgccca	CRISPR spacer
cataacttcttttacttcttctatttttcctttttct	Protospacer
***** *** ****************. .  * ..*

123. spacer 4.6|2569618|35|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019839 (Leptotrichia wadei strain JMUB3934 plasmid pJMUB3934p4, complete sequence) position: , mismatch: 11, identity: 0.686

actctctctaattactaattaattttttatttttt	CRISPR spacer
gccaatcaatattactaattaattttttttctttt	Protospacer
.*.  ..   ****************** *.****

124. spacer 5.12|2574319|34|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to CP027480 (Pseudomonas koreensis strain P19E3 plasmid p3, complete sequence) position: , mismatch: 11, identity: 0.676

caagattttgcttgcaattggctttaagtgttcc	CRISPR spacer
aaagattttgcttggaattggcattgggaccata	Protospacer
 ************* ******* **..*  . .

125. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP036488 (Rahnella aquatilis strain MEM40 plasmid pMEM40-1, complete sequence) position: , mismatch: 11, identity: 0.703

atatttacttttgccttttctgtctcagctttcaaaa	CRISPR spacer
gtttttacttttgccttatctgtctcggcgcggctga	Protospacer
.* ************** ********.** .    .*

126. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_017060 (Rahnella aquatilis HX2 plasmid PRA1, complete sequence) position: , mismatch: 11, identity: 0.703

atatttacttttgccttttctgtctcagctttcaaaa	CRISPR spacer
gtttttacttttgccttatctgtctcggcgcggctga	Protospacer
.* ************** ********.** .    .*

127. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_015062 (Rahnella sp. Y9602 plasmid pRAHAQ01, complete sequence) position: , mismatch: 11, identity: 0.703

atatttacttttgccttttctgtctcagctttcaaaa	CRISPR spacer
gtttttacttttgccttatctgtctcggcgcggctga	Protospacer
.* ************** ********.** .    .*

128. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034838 (Rahnella aquatilis strain KM12 plasmid pKM12v1, complete sequence) position: , mismatch: 11, identity: 0.703

atatttacttttgccttttctgtctcagctttcaaaa	CRISPR spacer
gtttttacttttgccttatctgtctcggcgcggctga	Protospacer
.* ************** ********.** .    .*

129. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034839 (Rahnella aquatilis strain KM25 plasmid pKM12v2, complete sequence) position: , mismatch: 11, identity: 0.703

atatttacttttgccttttctgtctcagctttcaaaa	CRISPR spacer
gtttttacttttgccttatctgtctcggcgcggctga	Protospacer
.* ************** ********.** .    .*

130. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034837 (Rahnella aquatilis strain KM05 plasmid pKM05, complete sequence) position: , mismatch: 11, identity: 0.703

atatttacttttgccttttctgtctcagctttcaaaa	CRISPR spacer
gtttttacttttgccttatctgtctcggcgcggctga	Protospacer
.* ************** ********.** .    .*

131. spacer 9.6|2612581|37|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032297 (Rahnella aquatilis strain ZF7 plasmid pRAZF7, complete sequence) position: , mismatch: 11, identity: 0.703

atatttacttttgccttttctgtctcagctttcaaaa	CRISPR spacer
gtttttacttttgccttatctgtctcggcgcggctga	Protospacer
.* ************** ********.** .    .*

132. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MN692968 (Marine virus AFVG_117M26, complete genome) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
gttttttttgaaaaaaattttaaaaattatttgaaa	Protospacer
. ...**** ****************** ***

133. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to MN694254 (Marine virus AFVG_250M1006, complete genome) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
gttttttttgaaaaaaattttaaaaattatttgaaa	Protospacer
. ...**** ****************** ***

134. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024317 (Borrelia miyamotoi strain Yekat-6 plasmid pYkt6-lp72, complete sequence) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
taatttttttaaaaaaattttaaaaaaatttgaaat	Protospacer
 . ..*********************  ***    *

135. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024391 (Borrelia miyamotoi strain Izh-4 plasmid pIzh4-lp72, complete sequence) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
taatttttttaaaaaaattttaaaaaaatttgaaat	Protospacer
 . ..*********************  ***    *

136. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010187 (Escherichia coli strain M6 plasmid A, complete genome) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
gactacagaaaaataaaatttaaaaatttttttctt	Protospacer
..*. .    *** *** ******************

137. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010207 (Escherichia coli strain M11 plasmid A, complete sequence) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
gactacagaaaaataaaatttaaaaatttttttctt	Protospacer
..*. .    *** *** ******************

138. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010197 (Escherichia coli strain M9 plasmid A, complete genome) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
gactacagaaaaataaaatttaaaaatttttttctt	Protospacer
..*. .    *** *** ******************

139. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024206 (Borrelia miyamotoi strain Izh-5 plasmid pIzh5-lp72, complete sequence) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
taatttttttaaaaaaattttaaaaaaatttgaaat	Protospacer
 . ..*********************  ***    *

140. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024334 (Borrelia miyamotoi strain Yekat-1 plasmid pYkt1-lp72, complete sequence) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
taatttttttaaaaaaattttaaaaaaatttgaaat	Protospacer
 . ..*********************  ***    *

141. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010222 (Escherichia coli strain M19 plasmid A, complete sequence) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
gactacagaaaaataaaatttaaaaatttttttctt	Protospacer
..*. .    *** *** ******************

142. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024352 (Borrelia miyamotoi strain Izh-16 plasmid pIzh16-lp72, complete sequence) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
taatttttttaaaaaaattttaaaaaaatttgaaat	Protospacer
 . ..*********************  ***    *

143. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP010214 (Escherichia coli strain M15 plasmid A, complete sequence) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
gactacagaaaaataaaatttaaaaatttttttctt	Protospacer
..*. .    *** *** ******************

144. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP017969 (Fusobacterium varium strain Fv113-g1 plasmid pFV113-g1-1, complete sequence) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
tcccctttttaaaaaagttttaataattcaaaatta	Protospacer
  **************.****** ****.    .*

145. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024372 (Borrelia miyamotoi strain Izh-14 plasmid pIzh14-lp72, complete sequence) position: , mismatch: 11, identity: 0.694

agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
taatttttttaaaaaaattttaaaaaaatttgaaat	Protospacer
 . ..*********************  ***    *

146. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_022551 (Blattabacterium sp. (Nauphoeta cinerea) plasmid unnamed, complete sequence) position: , mismatch: 14, identity: 0.611

agccctttttaaaaaaattttaaaaatttttttctt-------	CRISPR spacer
-------gaaaaaaaaattttaaaaattcttttaaaaaataaa	Protospacer
          ******************.****

147. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NC_013419 (Blattabacterium sp. (Periplaneta americana) str. BPLAN plasmid pBPLAN, complete sequence) position: , mismatch: 14, identity: 0.611

agccctttttaaaaaaattttaaaaatttttttctt-------	CRISPR spacer
-------gaaaaaaaaattttaaaaattcttttaaaaaataag	Protospacer
          ******************.****

148. spacer 12.13|2639526|36|NC_015949|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017256 (Clostridium taeniosporum strain 1/k plasmid pCt3, complete sequence) position: , mismatch: 14, identity: 0.611

-----agccctttttaaaaaaattttaaaaatttttttctt	CRISPR spacer
ccataaaaatttattaaaatttttttaaaaaatttt-----	Protospacer
     *.  .** ******   ********* ****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

91263 : 180194

unidentified_phage(20.0%)

transposase,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014041771.1\|91263_92250_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_014041772.1\|92291_95324_+	hypothetical protein	NA	NA	NA	NA
WP_014041773.1\|95357_96812_+	S-layer homology domain-containing protein	NA	NA	NA	NA
WP_014041774.1\|96887_98306_+	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	4.6e-33	32.4
WP_014041775.1\|98471_99491_+	rod shape-determining protein	NA	NA	NA	NA
WP_013433529.1\|99511_100279_+	flagellar basal-body rod protein FlgF	NA	NA	NA	NA
WP_041725585.1\|100435_101905_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_013433528.1\|102059_102863_+	flagellar basal-body rod protein FlgG	NA	NA	NA	NA
WP_014041778.1\|102887_103238_+	flagellar rod-binding protein FlgJ	NA	NA	NA	NA
WP_014041780.1\|103435_104251_+	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_014041781.1\|104252_105353_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_014041782.1\|105443_106211_-	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_014041783.1\|106267_107152_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_014041784.1\|107175_108129_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_014041785.1\|108283_109882_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_014041786.1\|110188_112510_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014041787.1\|112591_114877_-	transketolase	NA	NA	NA	NA
WP_014041788.1\|115214_116165_+	AEC family transporter	NA	NA	NA	NA
WP_014041789.1\|116157_117390_-	MFS transporter	NA	NA	NA	NA
WP_014041790.1\|117718_118741_+	rhamnogalacturonan acetylesterase	NA	NA	NA	NA
WP_014041791.1\|118881_120231_+	phosphoglucosamine mutase	A0A127AWJ1	Bacillus_phage	3.4e-25	26.4
WP_014041792.1\|120509_122345_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	5.3e-114	40.4
WP_156786151.1\|122690_122858_+	hypothetical protein	NA	NA	NA	NA
WP_014041794.1\|124953_126036_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	2.3e-45	32.5
WP_014041795.1\|126903_128142_+	AAA family ATPase	NA	NA	NA	NA
WP_014041796.1\|128146_128695_+	hypothetical protein	NA	NA	NA	NA
WP_014041798.1\|132829_134047_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.8e-55	34.1
WP_041725590.1\|134355_135663_+	hypothetical protein	NA	NA	NA	NA
WP_014041800.1\|135659_135899_-	hypothetical protein	NA	NA	NA	NA
WP_014041801.1\|135943_137179_-	DNA polymerase IV	NA	NA	NA	NA
WP_013433505.1\|137420_137750_+	hypothetical protein	NA	NA	NA	NA
WP_014041802.1\|137755_138454_+	hypothetical protein	A0A1V0E017	Clostridioides_phage	3.9e-09	25.5
WP_041725720.1\|139397_140405_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_014041804.1\|140625_141903_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014041805.1\|143275_144127_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_014041807.1\|145996_147532_+	methyl-accepting chemotaxis protein	NA	NA	NA	NA
WP_014041808.1\|147677_149069_+	oxaloacetate decarboxylase subunit alpha	NA	NA	NA	NA
WP_014041809.1\|149101_149458_+	OadG family protein	NA	NA	NA	NA
WP_013433496.1\|149492_149843_+	biotin/lipoyl-binding protein	NA	NA	NA	NA
WP_014041810.1\|149868_151005_+	sodium ion-translocating decarboxylase subunit beta	NA	NA	NA	NA
WP_014041811.1\|151121_151721_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_014041812.1\|152005_155047_+	S-layer protein	NA	NA	NA	NA
WP_013433492.1\|155343_155709_+	hypothetical protein	NA	NA	NA	NA
WP_041725592.1\|158129_158948_+	hypothetical protein	NA	NA	NA	NA
WP_013433489.1\|160998_161676_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.3e-37	39.8
WP_014041815.1\|161679_162858_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_014041816.1\|162878_166106_+	S-layer homology domain-containing protein	NA	NA	NA	NA
WP_013431467.1\|167658_168741_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	4.7e-46	36.6
WP_156786152.1\|169318_170686_+	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	3.2e-23	29.5
WP_013433482.1\|170709_171282_+	DUF4065 domain-containing protein	NA	NA	NA	NA
WP_014041820.1\|171380_172019_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_014041821.1\|172361_173786_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_014041822.1\|173957_174656_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.2e-31	35.7
WP_014041823.1\|174655_176887_+	ABC transporter permease	NA	NA	NA	NA
WP_014041824.1\|176958_177534_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_014041825.1\|177580_178921_-	glycoside hydrolase	NA	NA	NA	NA
WP_013433477.1\|179216_180194_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA

DBSCAN-SWA_2

875792 : 887937

Synechococcus_phage(22.22%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014042292.1\|875792_876449_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.5e-18	32.8
WP_014042293.1\|876445_877471_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.2e-67	45.0
WP_014042294.1\|877474_878899_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	4.7e-62	34.5
WP_014042295.1\|878880_881073_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.6e-160	40.8
WP_014042296.1\|881079_881778_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_013432717.1\|881781_882030_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_014042297.1\|882067_882787_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	3.0e-41	43.2
WP_013432719.1\|882909_884298_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	7.1e-55	33.1
WP_014042298.1\|884516_885746_-	PDZ domain-containing protein	W5SAB9	Pithovirus	1.2e-10	31.7
WP_014042299.1\|885837_887241_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	4.9e-43	38.1
WP_013432722.1\|887265_887937_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.4e-56	47.3

DBSCAN-SWA_3

921579 : 1002279

Klosneuvirus(25.0%)

transposase,integrase,tRNA

attL 989253:989312|attR 1002461:1002520

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014042328.1\|921579_924228_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.7e-180	44.1
WP_014042329.1\|924379_924757_+	desulfoferrodoxin	NA	NA	NA	NA
WP_013432757.1\|924832_926032_-	acetate kinase	NA	NA	NA	NA
WP_083825650.1\|926058_927090_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_013403138.1\|927256_927865_+	transcriptional repressor LexA	E5DV74	Deep-sea_thermophilic_phage	4.7e-19	40.1
WP_014042331.1\|927867_929148_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_013403136.1\|929238_929529_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_014042332.1\|929593_930532_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_014042333.1\|930556_932323_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	9.4e-68	30.6
WP_014042334.1\|932319_934911_-	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	6.9e-51	24.8
WP_014042335.1\|934914_936330_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_013403131.1\|936506_936704_+	alpha/beta-type small acid-soluble spore protein	NA	NA	NA	NA
WP_014042336.1\|936768_937200_-	ACT domain-containing protein	NA	NA	NA	NA
WP_014042337.1\|937266_938568_-	phenylacetate--CoA ligase	NA	NA	NA	NA
WP_014042339.1\|940933_942235_-	phenylacetate--CoA ligase	NA	NA	NA	NA
WP_013432769.1\|945067_945514_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_013432770.1\|945698_946160_-	transcriptional repressor NrdR	NA	NA	NA	NA
WP_013432771.1\|946156_947830_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_049783176.1\|948400_948577_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_049783106.1\|948577_948847_+	hypothetical protein	NA	NA	NA	NA
WP_014042341.1\|948819_950046_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	9.9e-16	32.5
WP_014042343.1\|951319_954052_-	UPF0182 family protein	NA	NA	NA	NA
WP_014042344.1\|954474_955410_-	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_014042345.1\|955424_955865_-	NfeD family protein	NA	NA	NA	NA
WP_014042346.1\|955886_958283_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.5e-84	35.5
WP_014042347.1\|958332_958920_-	hypothetical protein	NA	NA	NA	NA
WP_014041806.1\|959036_960476_-\|transposase	ISLre2-like element ISCla2 family transposase	NA	NA	NA	NA
WP_014042348.1\|960664_961069_-	TIGR04086 family membrane protein	NA	NA	NA	NA
WP_014042349.1\|961154_962345_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	3.9e-150	69.8
WP_014042350.1\|962513_963944_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_014042351.1\|964518_964935_-	YjbQ family protein	NA	NA	NA	NA
WP_014042352.1\|965082_966033_+	glycosidase	NA	NA	NA	NA
WP_014042353.1\|966099_968565_-	WG repeat-containing protein	NA	NA	NA	NA
WP_014042354.1\|968813_970472_-	biosynthetic-type acetolactate synthase large subunit	G9E4W7	Ostreococcus_lucimarinus_virus	2.0e-19	28.0
WP_014042355.1\|970499_972158_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_014042356.1\|972175_973057_-	branched-chain-amino-acid transaminase	NA	NA	NA	NA
WP_014042357.1\|974125_975085_-	2-hydroxyglutaryl-CoA dehydratase	NA	NA	NA	NA
WP_014042358.1\|975081_976233_-	hypothetical protein	NA	NA	NA	NA
WP_014042359.1\|976235_977237_-	hypothetical protein	NA	NA	NA	NA
WP_041725640.1\|977366_978854_-\|tRNA	lysine--tRNA ligase	A0A1V0SIS0	Klosneuvirus	1.7e-102	40.6
WP_013403857.1\|978877_979366_-	transcription elongation factor GreA	NA	NA	NA	NA
WP_014042363.1\|985127_986237_-	ABC transporter permease	NA	NA	NA	NA
WP_014042364.1\|986266_986989_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.8e-24	32.0
WP_014042365.1\|987020_988118_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_014042366.1\|988121_988733_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
989253:989312	attL	NA	NA	NA	NA
WP_014041988.1\|991119_992559_+\|transposase	ISLre2-like element ISCla2 family transposase	NA	NA	NA	NA
WP_014041901.1\|993354_993516_-	hypothetical protein	NA	NA	NA	NA
WP_014042369.1\|993856_994570_-	hypothetical protein	NA	NA	NA	NA
WP_041725754.1\|994879_995680_-	hypothetical protein	NA	NA	NA	NA
WP_014041821.1\|995850_997275_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_014042371.1\|997610_999434_-	DUF3854 domain-containing protein	A0A1S5RF71	Helicobacter_phage	3.0e-21	23.5
WP_014042372.1\|999527_999854_-	hypothetical protein	NA	NA	NA	NA
WP_014042373.1\|999995_1000217_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013432809.1\|1000371_1000578_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014042374.1\|1000981_1001311_-	hypothetical protein	NA	NA	NA	NA
WP_014042375.1\|1001319_1002279_-\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	1.2e-24	28.7
1002461:1002520	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1661556 : 1736466

Bacillus_phage(28.57%)

coat,transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013432103.1\|1661556_1662006_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_041725790.1\|1662012_1664181_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	U5J9N6	Bacillus_phage	7.8e-08	43.0
WP_013402756.1\|1664224_1664752_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	7.9e-23	41.5
WP_014042820.1\|1664928_1665621_-	stage II sporulation protein R	NA	NA	NA	NA
WP_014042821.1\|1665708_1667004_-	Ger(x)C family spore germination protein	NA	NA	NA	NA
WP_014042822.1\|1667000_1668101_-	endospore germination permease	NA	NA	NA	NA
WP_014042823.1\|1668097_1669693_-	spore germination protein	NA	NA	NA	NA
WP_014042824.1\|1669708_1669903_-	hypothetical protein	NA	NA	NA	NA
WP_013402750.1\|1670032_1670485_+	ACT domain-containing protein	NA	NA	NA	NA
WP_014042825.1\|1670514_1671771_+	homoserine dehydrogenase	NA	NA	NA	NA
WP_013429769.1\|1671800_1672724_+	homoserine kinase	NA	NA	NA	NA
WP_013432094.1\|1672820_1674050_+	aspartate kinase	NA	NA	NA	NA
WP_014042828.1\|1676364_1677099_-\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_014042829.1\|1677111_1677654_-	hypothetical protein	NA	NA	NA	NA
WP_014042830.1\|1679694_1680501_-	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_013432089.1\|1680648_1681047_+	hypothetical protein	NA	NA	NA	NA
WP_014042831.1\|1681139_1681703_+	DUF4364 family protein	NA	NA	NA	NA
WP_014042832.1\|1682149_1682767_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014042833.1\|1682826_1683108_-\|coat	spore coat protein	NA	NA	NA	NA
WP_014042836.1\|1684210_1684597_-	aspartate 1-decarboxylase	NA	NA	NA	NA
WP_014042837.1\|1684602_1685451_-	pantoate--beta-alanine ligase	NA	NA	NA	NA
WP_014042838.1\|1685450_1686245_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	M4QNT1	Ostreococcus_lucimarinus_virus	1.0e-50	39.7
WP_014042839.1\|1686213_1687089_-	Rossmann-like and DUF2520 domain-containing protein	NA	NA	NA	NA
WP_014042840.1\|1687407_1687926_+	ferritin	NA	NA	NA	NA
WP_014042841.1\|1688020_1688242_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_014042842.1\|1688285_1689182_-	hypothetical protein	NA	NA	NA	NA
WP_013432073.1\|1691124_1691340_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013432072.1\|1691830_1692046_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014042844.1\|1692635_1693046_-	PIN domain-containing protein	NA	NA	NA	NA
WP_013432070.1\|1693045_1693312_-	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_013432069.1\|1693441_1693723_-	hypothetical protein	NA	NA	NA	NA
WP_156786161.1\|1693830_1694259_+	hypothetical protein	NA	NA	NA	NA
WP_083825675.1\|1694378_1695581_-	hypothetical protein	NA	NA	NA	NA
WP_041725793.1\|1699998_1700265_-	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_014042847.1\|1700385_1701372_-	CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_014042848.1\|1701375_1701948_-	CRISPR-associated protein Cas4	NA	NA	NA	NA
WP_014042849.1\|1701950_1702814_-	CRISPR system precrRNA processing endoribonuclease RAMP protein Cas6	NA	NA	NA	NA
WP_014042850.1\|1702810_1704859_-	type I-D CRISPR-associated helicase Cas3'	NA	NA	NA	NA
WP_014042851.1\|1704881_1705526_-	type I-D CRISPR-associated protein Cas5/Csc1	NA	NA	NA	NA
WP_014042852.1\|1705543_1706527_-	type I-D CRISPR-associated protein Cas7/Csc2	NA	NA	NA	NA
WP_014042853.1\|1706542_1709308_-	HD domain-containing protein	NA	NA	NA	NA
WP_014042854.1\|1709422_1710397_-	WYL domain-containing transcriptional regulator	NA	NA	NA	NA
WP_014042855.1\|1713200_1713491_-	hypothetical protein	NA	NA	NA	NA
WP_014042857.1\|1714566_1718778_-	hypothetical protein	A0A2H4PQV1	Staphylococcus_phage	1.5e-26	29.8
WP_014042858.1\|1719574_1720867_-\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	3.2e-33	28.1
WP_014042121.1\|1721483_1722770_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.2e-16	26.0
WP_013432063.1\|1723792_1724053_-	hypothetical protein	NA	NA	NA	NA
WP_041725661.1\|1724049_1724331_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_013432061.1\|1724470_1725547_-	DUF4338 domain-containing protein	M1IPB2	Pelagibacter_phage	1.3e-16	26.2
WP_013432060.1\|1725950_1726454_-	hypothetical protein	NA	NA	NA	NA
WP_014042859.1\|1726560_1727442_-	hypothetical protein	NA	NA	NA	NA
WP_014041988.1\|1727690_1729130_-\|transposase	ISLre2-like element ISCla2 family transposase	NA	NA	NA	NA
WP_014042860.1\|1730902_1731484_-	hypothetical protein	NA	NA	NA	NA
WP_014042861.1\|1732351_1732762_-	hypothetical protein	NA	NA	NA	NA
WP_013432056.1\|1732758_1733169_-	hypothetical protein	NA	NA	NA	NA
WP_014041821.1\|1735041_1736466_+\|transposase	ISNCY family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1839514 : 1896545

Acanthocystis_turfacea_Chlorella_virus(12.5%)

coat,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014042925.1\|1839514_1840885_-\|tRNA	tRNA lysidine(34) synthetase TilS	M1IC97	Acanthocystis_turfacea_Chlorella_virus	3.5e-14	28.8
WP_014042926.1\|1840922_1841930_-	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_014042927.1\|1842024_1845450_-	transcription-repair coupling factor	NA	NA	NA	NA
WP_014042928.1\|1845453_1846023_-\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_014042929.1\|1846115_1847093_-	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	1.1e-44	36.3
WP_014042930.1\|1847210_1848608_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A0N7G7P8	Chrysochromulina_ericina_virus	5.9e-33	36.6
WP_014042931.1\|1848604_1849069_-	cytidine deaminase	A7KUY9	Bacillus_phage	9.1e-23	40.0
WP_013431971.1\|1849123_1849765_-	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_013431970.1\|1849803_1850250_-	ribose 5-phosphate isomerase B	NA	NA	NA	NA
WP_014042932.1\|1850279_1851077_-	MBL fold metallo-hydrolase	A0A2H4J3R0	uncultured_Caudovirales_phage	2.9e-32	33.7
WP_014042933.1\|1851098_1852358_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_083789057.1\|1852599_1853322_+	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_156786167.1\|1853414_1853549_-	potassium-transporting ATPase subunit F	NA	NA	NA	NA
WP_013289907.1\|1853645_1853876_-	YlmC/YmxH family sporulation protein	NA	NA	NA	NA
WP_014042934.1\|1854018_1855686_-	ribonuclease J	NA	NA	NA	NA
WP_014042935.1\|1855805_1856738_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	2.1e-34	35.1
WP_014042936.1\|1856738_1857986_-	protein translocase subunit SecD	NA	NA	NA	NA
WP_014042937.1\|1858111_1858627_-	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_014042938.1\|1858628_1859990_-	thioether cross-link-forming SCIFF peptide maturase	NA	NA	NA	NA
WP_013289901.1\|1860092_1860236_-	six-cysteine peptide SCIFF	NA	NA	NA	NA
WP_014041988.1\|1860411_1861851_-\|transposase	ISLre2-like element ISCla2 family transposase	NA	NA	NA	NA
WP_013431957.1\|1862036_1863008_-	class II fructose-1,6-bisphosphate aldolase	NA	NA	NA	NA
WP_014042939.1\|1863036_1863759_-	phosphatase	NA	NA	NA	NA
WP_014042940.1\|1863804_1864869_-	bifunctional phosphoglucose/phosphomannose isomerase	NA	NA	NA	NA
WP_014042941.1\|1865019_1867089_-	endo-1,4-beta-xylanase	NA	NA	NA	NA
WP_014042942.1\|1867103_1868303_-	ROK family transcriptional regulator	NA	NA	NA	NA
WP_014042943.1\|1868385_1869213_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_014042944.1\|1869251_1870142_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_014042945.1\|1870265_1871573_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_014042946.1\|1871870_1872566_+	hypothetical protein	NA	NA	NA	NA
WP_014042947.1\|1872575_1873274_+	endonuclease	NA	NA	NA	NA
WP_014042949.1\|1873614_1875315_-\|transposase	IS1182 family transposase	Q9MBP7	Staphylococcus_prophage	1.3e-82	36.2
WP_013431945.1\|1875448_1875901_-	ATP-binding protein	NA	NA	NA	NA
WP_013431944.1\|1876064_1876496_-	nucleoside deaminase	NA	NA	NA	NA
WP_014042950.1\|1879249_1880467_+\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	9.7e-56	34.2
WP_014042952.1\|1884881_1885556_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_014042953.1\|1885885_1887121_+	LL-diaminopimelate aminotransferase	NA	NA	NA	NA
WP_013431937.1\|1887132_1887453_+	heavy metal-binding domain-containing protein	NA	NA	NA	NA
WP_013431936.1\|1887477_1888266_+	type III pantothenate kinase	NA	NA	NA	NA
WP_014042954.1\|1888332_1889325_-\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_014042955.1\|1889371_1890340_-	hypothetical protein	NA	NA	NA	NA
WP_014042956.1\|1890330_1891332_-\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_014042957.1\|1891388_1892285_-	DUF2156 domain-containing protein	NA	NA	NA	NA
WP_014042958.1\|1892392_1892899_+	hypothetical protein	NA	NA	NA	NA
WP_014042959.1\|1892885_1893758_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_014042960.1\|1893964_1894942_-	zinc-dependent alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_014041897.1\|1895105_1896545_-\|transposase	ISLre2-like element ISCla2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

2194008 : 2259458

Bacillus_phage(18.75%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014043149.1\|2194008_2195241_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	I7II68	Campylobacter_virus	3.1e-09	26.0
WP_014043150.1\|2195233_2195644_-\|transposase	IS200/IS605 family transposase	W0UUZ0	Sulfolobus_monocaudavirus	1.5e-32	51.1
WP_013431670.1\|2195953_2196718_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-19	32.3
WP_013431669.1\|2196720_2197770_-	iron ABC transporter permease	NA	NA	NA	NA
WP_013431668.1\|2197811_2198957_-	iron ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014043151.1\|2199268_2200645_-	HAMP domain-containing protein	W8CYF6	Bacillus_phage	1.9e-36	32.6
WP_014043152.1\|2200634_2201330_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.4e-35	32.6
WP_013431665.1\|2201557_2202070_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_013431664.1\|2202259_2203384_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	Q332I1	Clostridium_botulinum_C_phage	1.0e-72	43.9
WP_013431662.1\|2203911_2204397_-	hypothetical protein	NA	NA	NA	NA
WP_148222719.1\|2204380_2205127_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_014043155.1\|2205322_2205874_-	DUF2680 domain-containing protein	NA	NA	NA	NA
WP_014043156.1\|2206090_2206744_+	response regulator transcription factor	W8CYM9	Bacillus_phage	5.4e-45	43.7
WP_014043157.1\|2206740_2208093_+	HAMP domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	2.7e-06	23.3
WP_014043158.1\|2208219_2209482_-	DUF2399 domain-containing protein	NA	NA	NA	NA
WP_014043159.1\|2209478_2213531_-	TIGR02680 family protein	NA	NA	NA	NA
WP_014043160.1\|2213558_2214740_-	TIGR02678 family protein	NA	NA	NA	NA
WP_014043161.1\|2214763_2216227_-	TIGR02677 family protein	NA	NA	NA	NA
WP_014043162.1\|2216326_2216902_-	hypothetical protein	NA	NA	NA	NA
WP_014043163.1\|2216996_2218037_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_014043164.1\|2218033_2219776_-	SpoIID/LytB domain-containing protein	NA	NA	NA	NA
WP_013404198.1\|2219920_2220541_+	potassium transporter TrkA	NA	NA	NA	NA
WP_013431650.1\|2220537_2221203_+	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_014043165.1\|2221386_2222901_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_014043166.1\|2222907_2223399_+	hypothetical protein	NA	NA	NA	NA
WP_014043167.1\|2223436_2223904_-	VanZ family protein	NA	NA	NA	NA
WP_014043168.1\|2224101_2225088_-	cellulase family glycosylhydrolase	NA	NA	NA	NA
WP_014043169.1\|2225170_2227303_-	NTP transferase domain-containing protein	G3MA50	Bacillus_virus	1.1e-22	31.6
WP_014043170.1\|2227344_2228538_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_014043171.1\|2228752_2230609_-	glycoside hydrolase family 15	NA	NA	NA	NA
WP_041725681.1\|2230842_2233284_-	glycoside hydrolase family 2 protein	NA	NA	NA	NA
WP_014041988.1\|2233611_2235051_+\|transposase	ISLre2-like element ISCla2 family transposase	NA	NA	NA	NA
WP_014043174.1\|2235470_2237093_+	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	5.5e-91	37.6
WP_014043175.1\|2237155_2238238_-	hypothetical protein	NA	NA	NA	NA
WP_014043176.1\|2238234_2238834_-	hypothetical protein	NA	NA	NA	NA
WP_013431617.1\|2238784_2239186_-	hypothetical protein	NA	NA	NA	NA
WP_014043177.1\|2239227_2240304_-	stage II sporulation protein D	Q2XU88	Pseudomonas_phage	3.9e-40	37.5
WP_014043178.1\|2240284_2242579_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_014043179.1\|2242797_2243466_-	phage shock protein A	NA	NA	NA	NA
WP_014043180.1\|2243502_2244837_-	hypothetical protein	NA	NA	NA	NA
WP_013431612.1\|2244863_2245418_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_014043181.1\|2245445_2246240_-	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	1.1e-07	35.5
WP_014043182.1\|2246246_2246720_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_014043183.1\|2246723_2246939_-	DUF3006 domain-containing protein	NA	NA	NA	NA
WP_014043184.1\|2246966_2248094_-	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	2.9e-22	30.7
WP_014043185.1\|2248110_2249055_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_014043186.1\|2249047_2249461_-	DUF1284 domain-containing protein	NA	NA	NA	NA
WP_014043187.1\|2249547_2250792_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_014043188.1\|2250975_2252253_+	methyl-accepting chemotaxis protein	NA	NA	NA	NA
WP_014043189.1\|2252572_2252911_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_014043190.1\|2252907_2253159_-	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_013431467.1\|2253559_2254642_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	4.7e-46	36.6
WP_014043191.1\|2257470_2258235_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	8.8e-55	46.1
WP_014043192.1\|2258255_2259458_-\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	4.3e-56	34.8

DBSCAN-SWA_7

2302311 : 2376624

Bacillus_phage(25.0%)

transposase,integrase

attL 2367500:2367559|attR 2376788:2376848

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014041821.1\|2302311_2303736_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_014043217.1\|2303906_2305577_+	alpha-glucosidase	NA	NA	NA	NA
WP_014043218.1\|2305746_2306151_+	transcriptional repressor	NA	NA	NA	NA
WP_013431563.1\|2306174_2306711_+	rubrerythrin family protein	NA	NA	NA	NA
WP_041725684.1\|2307145_2308615_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_014043221.1\|2309188_2310481_-\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	1.9e-33	28.1
WP_014043222.1\|2311179_2312559_-\|transposase	ISLre2-like element ISCla2 family transposase	NA	NA	NA	NA
WP_014043225.1\|2317382_2319074_-	phosphoenolpyruvate--protein phosphotransferase	A0A1V0SGR7	Hokovirus	8.5e-18	31.4
WP_014043226.1\|2319160_2320138_-	1-phosphofructokinase	NA	NA	NA	NA
WP_014043227.1\|2320165_2320918_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_014043228.1\|2321187_2321820_+	flavodoxin family protein	NA	NA	NA	NA
WP_014043229.1\|2323908_2325984_-	alpha-amylase	NA	NA	NA	NA
WP_013431467.1\|2326301_2327384_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	4.7e-46	36.6
WP_014043230.1\|2327609_2329481_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_041725685.1\|2329634_2330585_-	hypothetical protein	NA	NA	NA	NA
WP_156786170.1\|2341025_2341253_+	hypothetical protein	NA	NA	NA	NA
WP_013431549.1\|2341249_2342431_+	hypothetical protein	NA	NA	NA	NA
WP_013431548.1\|2342775_2343981_-	maltose ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014043231.1\|2344129_2345143_-	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	1.6e-16	24.7
WP_013431546.1\|2345149_2346772_-	alpha-glucan family phosphorylase	NA	NA	NA	NA
WP_014043232.1\|2346824_2347694_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_014043233.1\|2347693_2348602_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_014043234.1\|2348711_2350445_-	alpha-glycosidase	NA	NA	NA	NA
WP_014043235.1\|2350684_2351326_+	class II aldolase/adducin family protein	NA	NA	NA	NA
WP_156786171.1\|2351618_2351777_+	hypothetical protein	NA	NA	NA	NA
WP_014043236.1\|2351796_2352438_+	cobalamin-binding protein	NA	NA	NA	NA
WP_014043237.1\|2352494_2353013_-	nucleoside recognition protein	NA	NA	NA	NA
WP_014043238.1\|2353009_2353579_-	nucleoside recognition protein	NA	NA	NA	NA
WP_014043239.1\|2353699_2354806_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_014043240.1\|2355011_2356181_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_014043241.1\|2356182_2356875_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.3e-36	39.5
WP_014043242.1\|2356899_2358108_+	FtsX-like permease family protein	NA	NA	NA	NA
WP_014043243.1\|2359731_2360355_-	class I SAM-dependent methyltransferase	A0A1V0SKE1	Klosneuvirus	5.5e-07	25.9
WP_014043246.1\|2363969_2364194_+	hypothetical protein	NA	NA	NA	NA
WP_014043247.1\|2364308_2365853_+	alpha-amylase	NA	NA	NA	NA
WP_014043248.1\|2366771_2367353_+	Uma2 family endonuclease	NA	NA	NA	NA
2367500:2367559	attL	NA	NA	NA	NA
WP_014043249.1\|2368614_2369274_-	hypothetical protein	NA	NA	NA	NA
WP_014043251.1\|2370561_2371149_+	hypothetical protein	NA	NA	NA	NA
WP_014043252.1\|2371249_2371411_-	hypothetical protein	NA	NA	NA	NA
WP_156786179.1\|2371785_2373087_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_041725824.1\|2373086_2373911_-	DNA primase	A0A173H0P8	Pseudoalteromonas_phage	8.9e-29	37.2
WP_014043256.1\|2374094_2374334_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014043257.1\|2374640_2374853_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014043258.1\|2375254_2375584_-	hypothetical protein	NA	NA	NA	NA
WP_014043259.1\|2375679_2376624_-\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	1.1e-25	31.9
2376788:2376848	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_015949

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection