CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_015172	Syntrophobotulus glycolicus DSM 8271, complete sequence	4 crisprs	csa3,RT,cas3,WYL,cas5,cas8c,cas7,cas4,cas1,cas2,DEDDh,PD-DExK,cmr1gr7,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,cas6,cas8b2,DinG	2	12	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_015172_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015172_1

861106-861246

Unclear

Consensus_repeat	Method
TACCGTTGCGCCGACGTTATAAACACTCCCCGCCACGCCCCCGACATTCTCGCC	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NC_015172_1

>merge|NC_015172|1|861106-861246|CRISPRCasFinder
TACCGTTGCGCCGACGTTATAAACACTCCCCGCCACGCCCCCGACATTCTCGCCGCCGCTGACGCTGCCCGTGCTGTAGCAGTTTTCTACCGTTGCGCCGACGCTATAAACACTCCCCGCCACGCCCCCGACATTCTCGCC

>NC_015172|1|1|861106-861246|CRISPRCasFinder
TACCGTTGCGCCGACGTTATAAACACTCCCCGCCACGCCCCCGACATTCTCGCC	GCCGCTGACGCTGCCCGTGCTGTAGCAGTTTTC
TACCGTTGCGCCGACGCTATAAACACTCCCCGCCACGCCCCCGACATTCTCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015172.1\|WP_148228065.1\|846944_847454_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224399
NC_015172.1\|WP_013624088.1\|848692_849361_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_015172.1\|WP_013624087.1\|847485_848673_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226957
NC_015172.1\|WP_013624105.1\|873150_873975_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|130314
NC_015172.1\|WP_013624103.1\|871868_872042_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NC_015172.1\|WP_013624091.1\|850801_852535_+\|TerB-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379075
NC_015172.1\|WP_013624104.1\|872197_873154_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NC_015172.1\|WP_013624094.1\|856438_857011_-\|hypothetical-protein	unknown	unknown	unknown
NC_015172.1\|WP_013624101.1\|868367_869474_+\|two-component-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|274368
NC_015172.1\|WP_041445043.1\|867693_868371_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_015172.1\|WP_041444629.1\|869760_871587_-\|LTA-synthase-family-protein	unknown	unknown	gnl\|CDD\|224287
NC_015172.1\|WP_013624090.1\|849545_849815_+\|hypothetical-protein	unknown	unknown	unknown
NC_015172.1\|WP_052298604.1\|846483_846915_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224399
NC_015172.1\|WP_013624086.1\|845049_846447_+\|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl\|CDD\|100091
NC_015172.1\|WP_013624096.1\|863736_864099_-\|hypothetical-protein	unknown	unknown	unknown
NC_015172.1\|WP_013624098.1\|866231_866960_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225818
NC_015172.1\|WP_013624093.1\|853860_856026_+\|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224122
NC_015172.1\|WP_013624099.1\|866989_867163_-\|transposase	unknown	unknown	unknown
NC_015172.1\|WP_148228172.1\|864249_866229_-\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|340412
NC_015172.1\|WP_013624092.1\|852535_853864_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|378508

Protein	Function_ID	Function_description	E-value
NC_015172.1\|WP_148228065.1\|846944_847454_+\|hypothetical-protein	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	1.18422e-39
NC_015172.1\|WP_013624088.1\|848692_849361_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.90812e-101
NC_015172.1\|WP_013624087.1\|847485_848673_+\|ABC-transporter-permease	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	7.90619e-20
NC_015172.1\|WP_013624105.1\|873150_873975_+\|ABC-transporter-permease	gnl\|CDD\|130314	TIGR01247, drrB, daunorubicin resistance ABC transporter membrane protein. This model describes daunorubicin resistance ABC transporter, membrane associated protein in bacteria and archaea. The protein associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	1.10859e-17
NC_015172.1\|WP_013624103.1\|871868_872042_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	1.83168e-07
NC_015172.1\|WP_013624091.1\|850801_852535_+\|TerB-N-terminal-domain-containing-protein	gnl\|CDD\|379075	pfam13208, TerB_N, TerB N-terminal domain. The TerB_N domain is found N-terminal to TerB, and TerB_C containing proteins. It has a predominantly alpha-helical structure and contains an absolutely conserved glutamate. The presence of a conserved acidic residue suggests that it might chelate metal like TerB. These proteins occur in a two-gene operon containing an AAA+ ATPase and SF-II DNA helicase suggesting a role in stress-response or phage defense.	1.3937e-39
NC_015172.1\|WP_013624104.1\|872197_873154_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	6.23116e-95
NC_015172.1\|WP_013624101.1\|868367_869474_+\|two-component-sensor-histidine-kinase	gnl\|CDD\|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	1.34335e-61
NC_015172.1\|WP_041445043.1\|867693_868371_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.66815e-80
NC_015172.1\|WP_041444629.1\|869760_871587_-\|LTA-synthase-family-protein	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	2.43594e-92
NC_015172.1\|WP_052298604.1\|846483_846915_+\|hypothetical-protein	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	2.35789e-45
NC_015172.1\|WP_013624086.1\|845049_846447_+\|phosphomannomutase/phosphoglucomutase	gnl\|CDD\|100091	cd03089, PMM_PGM, The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a bisphosphorylated sugar intermediate. The reaction involves two phosphoryl transfers, with an intervening 180 degree reorientation of the reaction intermediate during catalysis. Reorientation of the intermediate occurs without dissociation from the active site of the enzyme and is thus, a simple example of processivity, as defined by multiple rounds of catalysis without release of substrate. Glucose-6-phosphate and glucose-1-phosphate are known to be utilized for energy metabolism and cell surface construction, respectively. PMM/PGM belongs to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the phosphoglucomutases (PGM1 and PGM2). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NC_015172.1\|WP_013624098.1\|866231_866960_-\|response-regulator-transcription-factor	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	1.90402e-32
NC_015172.1\|WP_013624093.1\|853860_856026_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|224122	COG1201, Lhr, Lhr-like helicases [General function prediction only].	1.98769e-131
NC_015172.1\|WP_148228172.1\|864249_866229_-\|GHKL-domain-containing-protein	gnl\|CDD\|340412	cd16935, HATPase_AgrC-ComD-like, Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Staphylococcus aureus AgrC and Streptococcus pneumoniae ComD which are involved in quorum sensing. This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) including Staphylococcus aureus AgrC which is an HK of the accessory gene regulator (agr) quorum sensing two-component regulatory system (TCS) AgrC-AgrA. The agr system plays a part in the transition from persistent to virulent phenotype. This family also includes Streptococcus pneumoniae ComD HK of the ComD-ComE TCS, involved in quorum sensing and genetic competence.	6.26382e-38
NC_015172.1\|WP_013624092.1\|852535_853864_+\|ATP-binding-protein	gnl\|CDD\|378508	pfam10923, DUF2791, P-loop Domain of unknown function (DUF2791). This is a family of proteins found in archaea and bacteria. This domain contains a P-loop motif suggesting it binds to a nucleotide such as ATP.	0

>NC_015172.1|WP_013624094.1|856438_857011_-|hypothetical-protein
MNISFGSINFTRTPGENANFGNHKTADFSAVNSNIQKQVVYLKTDDMLYSGGNGTGLSFYIKYADESSTDNPVVLAKGVDEKGNKFEQKIYINHINPSDASLVEMRALEAYCHADKSSGLSSLPPETGTMGLTDRSNFLEMLKNNIRDLTTLGRQDLSTIYLNHLQVYSHFAKKGSTTGGLGSVKNLWQG
>NC_015172.1|WP_013624093.1|853860_856026_+|DEAD/DEAH-box-helicase
MNAFEKLAPFIQDYIYRNNWEELREVQVAACDVILHTDNNLLIATPTASGKTEAAFLPVITELYHKPSSSVGVLYIAPLKALINDQFVRIEELLEEAYIPVTKWHGDASQSLKNKLLKNPKGIMQTTPESLEAMLMKRKQQAMKLFSDLRFIIIDEVHHFIGEDRGVQLLSLLERLQNLIGFSPRRIGLSATLGDGPAAEQWLNSGTPRTCVTPDVGTERRKAMIMISHFYTLPGSVDQERQSALGFFESLYSLTRGKKSIVFSNSRSDVERNMVNLKDIAEKRREPDVFLVHHGSISASNREYAETQMKFSDLPLVTGATVTLELGIDLGDLERIVQTGCPHSVASLAQRLGRSGRRGGVSEMCFLFEEEKKSEGIEFYQAINWLFVKCIALIELYRENWLEPIAADRYPYGVLYHQTMSFLYSHGEAKPELLAQSILSEAVFADVSQEDYKILLRDMLEKEQLERTSSGGLLVGAKGEILTNHYHFYSVFESPAEYSVRDGSQEIGTLSKPLPPDTTFVLSGKTWSVVEVDQEQKIIDVTSAKGKPPTVWDGTGGGFEHTRVLQKMREVIAGPTEYPYLHPSAASRLNEIRLTIRQTRLLENPVFEISPDTFGLALWLGTKAANALDLALTVLLPQRQYTPPYWPFLIVKNVGRDALLQALEHIKTVPLSISDLRIPDGIKVEGKYNDFVPPELLRKQYAAKTIDIAEMQREMTKNKEE
>NC_015172.1|WP_013624092.1|852535_853864_+|ATP-binding-protein
MSATNKIPPRVAGTLLNALKGGVVPRTGLGYITVGRKDEIDALLHDVETITIGGASFRFIVGKYGAGKSFLLQTIRNYAMERGFVVVDADLSPERRLVGNKGEGLATYKELMKNLSTHTSPDGGALSLLLQKWIAALKTEVMIENSLSADSPQLNEFVELKIHQTVNELETIVHGFDFARIISLYWKATVNEDDEAKRKTLKWLRGEYPTKTEAKQELGVGVIITDDDWYEYIKLFSMFVVKAGYKGMIMMIDELVNLFKIPNSVSRQNNYEKILTIYNDVMQGKAQYLGVIMGGTPQCIEDTRRGVFSYEALKSRLESSRFADGATRDLLAPIIRLKTLTPEEMYFLVQKLESIHALVYKYEPKLKSESLQYFIKTEFARVGAGQNITPREIIRDFIEILNIILQNPEKSLEGILGGENFEYAASSANDEKIQEEFKGFEI
>NC_015172.1|WP_013624091.1|850801_852535_+|TerB-N-terminal-domain-containing-protein
MANIHALMTLINKIFPNENCTRDNIAVFIRRLALKDVSQNHEHFASVQPPQENQSGKYSPEKITQKPPARGPQSEPYATFKKMRQIGGVREGYLSYYADDAEIFCKQAQLMKDFTDDDDRKIPLDPYCATYLKMDDAQLRTYFTWRTKVRQGVIEDTSLSYAFCYVFELLNDVGVSSPAEAIGKLIALWTAFRRYDEKIDVYLREWIRDYYVVHKPQFAVEFTDLSRGFPVPYHSEDVALLAKAKSCSWDDLRVIEASSSFRITNGQFYKATDQAMIEKCACFVIQELAKLFKSGGVDLRKMFWENRREKIYSLFRGAVHRKTAIQPITVQLDDFETIKLNSRGWYREYLTLTQYRSVIGYILKSIEIKMREHFGYKRSLQMPNISQVENSLINSEPDKFTYFTRPTMDRLKVWKAKAFSVISGTEFEPAIVRAIAEYCKLAHLVSVNGVVKEIKPVEIDLSKLKDIEKEHMETAAKLIVEEQPAPVAEVPPPAAVAPDLEIAGMAGFVDSLPEEGRTLLITLLNGGQVPPNSELLIETINAKALEVIADHMIDDSESVPYVYDDYTEELKSWLGGQ
>NC_015172.1|WP_013624090.1|849545_849815_+|hypothetical-protein
MISIISAITQLTVSTVTTATSLAARFGLIVTITLIALLISKQLTEAVSMNSATSELTLSGLLDRVLNVGIVPLLMVFVSIVFVKILHVL
>NC_015172.1|WP_013624088.1|848692_849361_+|ABC-transporter-ATP-binding-protein
MQTDILISVKKLTKVYGKGNLALKVLDVKNLEIRRGELVALTGPSGCGKTTLLNLLGALDRPTAGDIFFEGQRLALKREAALCGFRRKKIGFIFQAYHLIPTLSALKNVLAPAFPLGKDYRQRALELLRLVSLAGKEGRRPGELSGGEQQRVAIARALLLDPDLILADEPTGNLDSATGAGIMALLKNLNQRGKTVLVATHDQRVAEECDRKIRMMDGRISQ
>NC_015172.1|WP_013624087.1|847485_848673_+|ABC-transporter-permease
MSLLFFSIQNAFRKKAVAVLAVLGVAFGTALMTILFSLSAGMDHRVEGTFRELSNRVTISGRDAIFGGLYLGMGTKPIPSSSIEAIRDIPHVEKVYSQVSVVLRPQNNDYSMPLFGYGQEEIRDLANNPYNKIIEGSAPGNDQEMIIGKSLQEYMNLLNSPFAIGKVYPFLILEEGQAKKLELKVVGLYQTGNEVLDGAFSGSDKLARQIGRIPEGSVSAINVSVDGVDHVEAAAEAIKQELAGKKPELQVVVPGEVLNPVRNILEVLGKFLIAVSLVAVVAGGLSIMVVMLLSVINRMREFGILKALGWTPADIIFMVLVESLTLSLFGAALGIALGWAGVAVTRVFIAADIAVLSGQVMLSVLLAGILIGAAGGIYPAWCANSAAPVKILREV
>NC_015172.1|WP_148228065.1|846944_847454_+|hypothetical-protein
MRISVQPGDFFFIPSGTVHALGKGIVLLEIQQNSDLTYRIYDYNRIGLDGKKRNLHLAKALDVMTFEAARYHGKRSAGGEPGFKTTLASCRHFTVEKWLIQDSWDLFSLDGFILICVIKGKGELLFEDNALRLSKGSSIMIPVNMGTYQIKGNIEAIASYVHKDEGIRT
>NC_015172.1|WP_052298604.1|846483_846915_+|hypothetical-protein
MKPYPLLFGPSFQERIWGGSKLKKIFHSADLEGNIGEAWVISDHPHGKSLIVNGELAGKALSDLLDLCPGWFGRSPIRSFPLLVKLLDSREDLSVQVHPDDEYASRNEKGESGKTECWYIMESEPGAEIVFGHQAAKKKNLSN
>NC_015172.1|WP_013624086.1|845049_846447_+|phosphomannomutase/phosphoglucomutase
MGTLNEQIFRQYDIRGVAERDLTDETVILLGKAFGTAAIQKGSYQVLLGRDNRLSSERLRDALVKGLMAVGCDVLDIGLVVTPVLYYARFYYARLCLGIDAAVMITGSHNPPDENGFKLALGAGTIYGDEIQKLKELMLAGEFRYGSGSLEPVNCIPPYLKMLREKIQLGPRRLKVAVDCGNGTAALFAEKILADWGCEVIPLYCQSDGSFPNHQPDPVKTANLAELKKAVLEEKADLGLAFDGDADRIGVVDDAGKVIWGDVLMCLYWREIMPKYPGAKAIVEVKCSQALVDEVERLGGKPFFYKTGHSLIKAKMKEIGAVFTGEMSGHIFFADEYYGFDDAFYAAGRLLRLLSHSDGPLSKMLSAIPKYYSTAETRVTCPDWDKFKVVKGLAERFQRDYPVIDVDGARVLFGDGWGLVRASNTQPVLVARCEAKTEEGLQRICSMMKEALREFPEVEDFEWEE
>NC_015172.1|WP_013624096.1|863736_864099_-|hypothetical-protein
MLYQLYPQSGRTKVFTDKQSGIKFPCLTIAEIKARYPDGCFTVVGETGGFASGGDCPDTLASDGGKTVPVLPRGSHIRPWERVAGYIAVDRDTYVAAVKSAAPAFLWKLRFFRARRRQDK
>NC_015172.1|WP_148228172.1|864249_866229_-|GHKL-domain-containing-protein
MVSAERKIRLSLIAGLVFILLFAHIPVLYTALYHPLTGAQAAENGRMDGAGFTAGALVLDGEWEFYWDRLIVTEQSSGDPPDFLIRAPGYWSEYQIGGVHLPAQGVASYRLIVDGLSRSNPVTAYIPDFGSAYRVFVDGVLTAGSGTVSRNIEDVFTVPQAKLYPVTLSGAETHEIVIELATARFSGLYMAPVLADYHDTIQQSEIRESIRFILYGVVLFSFFAFIALFVLSRGKKLRVAYLPAIMLLILLRIMLSAEFYGFWQSSLFFGLSYEDSNPLLYLVTFILKFLLIFLIQEQFGVAFSKREKAFFFLYYAAIYLIYLFTPFDLYNRYLSLVLPVAAFALEVYGFIKVYRGRRRIKRYGLLIYWGVSLAVAGLIADCYYLGGNVYPNLSLALLVMLSACLLLVGLAYALRLADQYRDLAVADSEFRQARAQIAMQTEYYDALNGQMNEIRAIRHDTRHFIDVLGTLADEGRYDELRRFLGEYAERADTEPLPVFCQNTVANSILGYYALKARTKEIPFRCVSVIPKELPLSDGDLCVVLGNALENALEACAKPAVQSGRFIAVQAGTAGGQFLIKIENSYDGFVSIKDGELLSSKGGGAHGIGLQNIRRVVKSCGGFVKIDRTATTFTLMVACPHPVKAEAAPLHDSPGGAPHQ
>NC_015172.1|WP_013624098.1|866231_866960_-|response-regulator-transcription-factor
MPIHITICDDSQEDISRLSGALRAYDPAFAITSFTDSRTLLDELADTRFTADILFLDIYMPGLDGIETARKIRAQRPDVKIIFVSTSREHYPQAYEVFAFNYLVKPFAKEQLDRILARAIRESNLENGHKIRFSYKSALHTVDCRDILYLESSDKRILFHLADGGTLQRYGKLDDMVGELPEQAFIRCHQSFVVNTAHIRELGESYFRVGQALIGISKKHAKFAKEQYYAYLFSHMDRGAPE
>NC_015172.1|WP_013624099.1|866989_867163_-|transposase
MDYISAREAADKWGITSRMVNYHCAAGRIEGARKIGNIWAVPQDAPKPDDGRKRPKK
>NC_015172.1|WP_041445043.1|867693_868371_+|response-regulator-transcription-factor
MSKIMIVDDDPNIRELVLALLHRSGFAACEAADGREALQKMLNDNPDLVIIDVMMPNMDGFELCRHLRRYYENLPVIMLTAKGELASKVKGFGLGADDYLTKPFEGDELIARVQALLRRYKIEASQVIQTGNVLIDKNSYSITLNGVREDIPLKEFELIFKLAGFPGKTFSRNQLIEDIWGVDFEGNERTLDVHVNRLRDRFPEETAGFKITTVRGLGYRLEVMS
>NC_015172.1|WP_013624101.1|868367_869474_+|two-component-sensor-histidine-kinase
MRQRPQPPQPSPETQQPWPRRPHAVLSSLAAVLSFALCFAGGYMLMTVLYRRTGTPPEFWRHIFSGVMGLVIFAGAISLVRVAAVRHSHKFGERQGMNSQLLNAMTRIAQGDFDVFIEPRDHLFRDIVEGVNKIAKELGSLEQLRQDFISNVSHEIQSPLTSISGFAALLKNDALTAEQKTHYLGIIETESKRLSALSDNLLKLSALETGSESLARKEYRLDKQLEDIALMLEPQWSAKDIALEADLEKLTIQGDEGLLSQVWVNLLHNAVKFTPGGGVIRIELKAGQGNVCCRISDTGTGIAPEDQIHIFERFYKVDKSRDRALGGNGLGLSLAKKIVELHGGQITPQSAIGKGTTFTVTLPQNQSG
>NC_015172.1|WP_041444629.1|869760_871587_-|LTA-synthase-family-protein
MKKYHLLRLGTLEIPLTLSIILIKARLMMYHLNLELPWKILLFNCGLLMVLTAGAYLMRPLFRRGFLCLLNLSCSFLFFTDLLHYRYFNIPLTAYSFLQTSNLNGLGESILALARMSDLLLFTDLLIWPVFFFFTAASKLPKSRFIFAFQLILGLALTCFYPVQQTYYEKNDIFRRFDTAMTFHHFGPLGFHSVDTAYYLMDKNIALTDETEDLILAWFDNREQPDADQFFSALQGGSKGKNLIVIQVESLQNFVIGQTVAGQPITPNLNELLGHSFYYRHFYPQTVDGNSSDAELVVNSSLYPIRKGSTFFSYPGNQYHSLPLLLKPYGYQTVAVHSDEASFWNRHLVYPNLGFDEFWDIDKFAQTDLVGMGLSDMAMFEQSAAMLKELPQPFYSFIITLTSHYPYSMPSDQQFLELPPALDGSHVGNYLQAVRYTDQAIGGFMQELKQNGLLDNSLVVIYGDHDGLFERDKPQLEELWAGKTISGEEWVREYMPVPLIIYQPDFEGKRPGGYGGQVDVLPTIAYLMGFEQEAAHYAMGKNLLTPAGGFAIIPRGDYIKQMARVTPDRIDYDWDPDSEVGQTLQVADLIIRTNFFAISQRAASHAEN
>NC_015172.1|WP_013624103.1|871868_872042_+|type-II-toxin-antitoxin-system-HicA-family-toxin
MKRRDLVRIRESNGFKKVREGDHSIYKAPNKRAVQVPRHREINEITAQQILKDAGLK
>NC_015172.1|WP_013624104.1|872197_873154_+|ATP-binding-cassette-domain-containing-protein
MPMILVEELIKKYDKAKTPAVKGVSFAVEEGELFAFLGPNGAGKTTTISILTTTLAKTSGTVTIAGYDVEKEAKQVREKVGIIFQQPSLDLQLSAEENIRFHACLYGMFSYRPTFRLMPSEYRKRVLELAEIVGIQEALFKPVKKMSGGMQRKLEIIRSLIHTPAVLFLDEPTQGLDAVSRRSLWEYINSMRQEHGTTVFLTTHYIDEAEQVDKVCVINHGRIAGCSSPEEMKRSLLRQELILDAEDREGLTSELADLGLFYQQDEQKNGPIVVPDQDMTVQEIIAGLKTKLTVLKINEPSLEDAYVEYLRKTGGAVA
>NC_015172.1|WP_013624105.1|873150_873975_+|ABC-transporter-permease
MSEIVSHPAAHQSRLGREINAVISIAARDITIALRSPASIIMSFVMPLIMMGMLGGSLAQNMAGGLGFDYSKFMLVGMLVNMLFMVTTIGMTSLVEDHTTDFTQEMLVSPVSRYAIVLGKIFGSSFGAVVSMAGTLIVGLVMGITLSPGQLLMILALSPLMCLSGGALAMIIIGVVKSNKTANIAVMLVTMPQMFLSGAIIPINNSSGILYVLSHAMPMTYCLDLARAVVYAGTPEYSRVVLFNPAVNFIAIAVLAVICLVIGTFLFARSEKNR

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Crispr_ID: NC_015172_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015172_2

894822-897862

TypeI

I-C

Consensus_repeat	Method
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CRISPRCasFinder
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CRT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	PILER-CR

46 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3,WYL

The CRISPR arrays of NC_015172_2

>merge|NC_015172|2|894822-897862|CRISPRCasFinder,CRT,PILER-CR
GTCGCACCCCGCAAGGGTGCGTGGATTGAAACCTGTACTTATGAGAATCTATTGATTATCATCCCACGTCGCACCCCGCAAGGGTGCGTGGATTGAAACCCTCATAGGAATCTAGTTTAAATTCAATAAAATCGTCGCACCCCGCAAGGGTGCGTGGATTGAAACTCTATCATTTTTGGCTCAAAAGCATTTCTGAGCGTCGCACCCCGCAAGGGTGCGTGGATTGAAACTGAGAAAAAATGATTGTCGGCCTGTCCATCTTTGTCGCACCCCGCAAGGGTGCGTGGATTGAAACTCGAAAACCCTTGATTGGTAATATTCGTTAAAGTCGCACCCCGCAAGGGTGCGTGGATTGAAACAGCTAATTCGGCTTGTGATAAGTCATTTCCGATGTCGCACCCCGCAAGGGTGCGTGGATTGAAACACTAATCCCGCCCTCTAAAATCCATAATTCCAAGTCGCACCCCGCAAGGGTGCGTGGATTGAAACATACATTTCGATCTGGAACGATAAAATCACGGCGTCGCACCCCGCAAGGGTGCGTGGATTGAAACCAGAAGGGCGTTCGCTATGGCACAGGCCAGGAAAGTCGCACCCCGCAGGGGTGCGTGGATTGAAACAGACCAGGACCCTTCGCGGCCAGGCTTTCTTCAGTCGCACCCCGCAGGGGTGCGTGGATTGAAACAAGAACAGCGCGTCCCAGGAGTACGGAACCGCCAGGTCGCACCCCGCAGGGGTGCGTGGATTGAAACAGGTCCGCTTTGTCGACAGCGAATGGACGGTCGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTGGGTTCCAGGATCACGCCGGTCTGTTTGTTCGTCGCACCCCGCAGGGGTGCGTGGATTGAAACAGGTTGACCTTCCAGAAGCGGTCGGCGTAGGGGGTCGCACCCCGCAGGGGTGCGTGGATTGAAACCAGGGTGTCGATCGCTCTTTTCGTCCTGGCGGTGTCGCACCCCGCAGGGGTGCGTGGATTGAAACCGGCCCCGTTCGTCAGCATGGCCGAAGGCGACGAGTCGCACCCCGCAGGGGTGCGTGGATTGAAACCGGCCTGACCGGAAGAAAGAAGGTGTTAAACATGGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTTCGGCTGGCGAACGGTCCTGAACGAGTACCGGAGTCGCACCCCGCAGGGGTGCGTGGATTGAAACAGCTTGCGTCTTCGCTTCCGCCATTCTGGGCCGGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTTCCTGGCGCTGGCTTTCGCGCCCTTCACAAAAGTCGCACCCCGCAGGGGTGCGTGGATTGAAACATCGTGTTTCCCCCTTTTGACAGAAAAAAGGTCGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTCAGATATGTTTATCTAATTAGATTTTAGTACTTGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTTACCATATCCCAAACAGGAAGAATTATTTTATGTCGCACCCCGCAGGGGTGCGTGGATTGAAACAACATTAAAATCCGAATACCCAATATTTATAGCGTCGCACCCCGCAGGGGTGCGTGGATTGAAACCTCATATCTGTTATTGTCATATTATATCGGGCGCCGTCGCACCCCGCAGGGGTGCGTGGATTGAAACAAAATTACATTGACATCGAAGCCGATAACTGGGCAGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTTGAGATTATTGTTTTGTTATGATTATGATTTGGTCGCACCCCGCAGGGGTGCGTGGATTGAAACCCGCTGCTTGGCCTTTTGGCTGTCTAAATCGTCGTCGCACCCCGCAGGGGTGCGTGGATTGAAACACGTCGAGAGCCAAATCATTCCCGACATCCCCGACGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTCTTTTACCTCCGGCCATTTGCTTTTAGCCATCGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTAACTAGGATCGCTGAAAATAATTGGCCTGGCGTGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTTCTTTGCTAAGATTTTTTAATTCTGCTGTGTCCGTCGCACCCCGCAGGGGTGCGTGGATTGAAACAATCTTAAATTCCTTAAAGGCCTGCAAGATCATGGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTTCTAGCCATTTTTCTATGCACGGCAAACAGGTGTCGCACCCCGCAGGGGTGCGTGGATTGAAACCTCGGTTTGAATCATTTCAGGACGCGCGGGACACGTCGCACCCCGCAGGGGTGCGTGGATTGAAACGGGCATTATACTTTAGGCATACCTATTAGGGTTGTCGCACCCCGCAGGGGTGCGTGGATTGAAACCGCATTATGGTCTGGATAATAGCGCGTTACGAAGTCGCACCCCGCAGGGGTGCGTGGATTGAAACATTTCAAGCCCCGTGTTAAAAAAGCAGTATTGGGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTAGCGAAGTCCATGCTTGACCTTGGCCCCGCGTGTCGCACCCCGCAGGGGTGCGTGGATTGAAACCAGCCGTTCAAAGTAATTATCGTCTACTATAACGTCGCACCCCGCAGGGGTGCGTGGATTGAAACAGCGTCGGTCTCTGCGATTTTGCTGATGTATTTGTCGCACCCCGCAGGGGTGCGTGGATTGAAACAAAGAACAAAGTTTAAGGAATTATGCACTTTTTGTCGCACCCCGCAGGGGTGCGTGGATTGAAACGAAAAAGCGGGATTGATTGTATACTGCAAAGATGGTCGCACCCCGCAGGGGTGCGTGGATTGAAACTTCTTTTTTCCTCCCCTCCCCCACTCCGTAACATGTCGCACCCCGCAGGGGTGCGTGGATTGAAACATAGCTTTCTGCCATGGCTCTGAACCAGTCTCCCGTCGCACCCCGCAGGGGTGCGTGGATTGAAACGAAGTAATCGGTCATCAGAAAAAGTTTGATAGGTCGCACCCTTCATGGGTGTGTGGATTGAAAC

>NC_015172|2|2|894822-897862|CRISPRCasFinder
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	CTGTACTTATGAGAATCTATTGATTATCATCCCAC
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	CCTCATAGGAATCTAGTTTAAATTCAATAAAATC
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	TCTATCATTTTTGGCTCAAAAGCATTTCTGAGC
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	TGAGAAAAAATGATTGTCGGCCTGTCCATCTTT
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	TCGAAAACCCTTGATTGGTAATATTCGTTAAA
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	AGCTAATTCGGCTTGTGATAAGTCATTTCCGAT
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	ACTAATCCCGCCCTCTAAAATCCATAATTCCAA
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	ATACATTTCGATCTGGAACGATAAAATCACGGC
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	CAGAAGGGCGTTCGCTATGGCACAGGCCAGGAAA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGACCAGGACCCTTCGCGGCCAGGCTTTCTTCA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AAGAACAGCGCGTCCCAGGAGTACGGAACCGCCAG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGGTCCGCTTTGTCGACAGCGAATGGACGGTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TGGGTTCCAGGATCACGCCGGTCTGTTTGTTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGGTTGACCTTCCAGAAGCGGTCGGCGTAGGGG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CAGGGTGTCGATCGCTCTTTTCGTCCTGGCGGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CGGCCCCGTTCGTCAGCATGGCCGAAGGCGACGA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CGGCCTGACCGGAAGAAAGAAGGTGTTAAACATG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCGGCTGGCGAACGGTCCTGAACGAGTACCGGA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGCTTGCGTCTTCGCTTCCGCCATTCTGGGCCG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCCTGGCGCTGGCTTTCGCGCCCTTCACAAAA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ATCGTGTTTCCCCCTTTTGACAGAAAAAAGGTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TCAGATATGTTTATCTAATTAGATTTTAGTACTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTACCATATCCCAAACAGGAAGAATTATTTTAT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AACATTAAAATCCGAATACCCAATATTTATAGC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CTCATATCTGTTATTGTCATATTATATCGGGCGCC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AAAATTACATTGACATCGAAGCCGATAACTGGGCA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTGAGATTATTGTTTTGTTATGATTATGATTTG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CCGCTGCTTGGCCTTTTGGCTGTCTAAATCGTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ACGTCGAGAGCCAAATCATTCCCGACATCCCCGAC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TCTTTTACCTCCGGCCATTTGCTTTTAGCCATC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TAACTAGGATCGCTGAAAATAATTGGCCTGGCGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCTTTGCTAAGATTTTTTAATTCTGCTGTGTCC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AATCTTAAATTCCTTAAAGGCCTGCAAGATCATG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCTAGCCATTTTTCTATGCACGGCAAACAGGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CTCGGTTTGAATCATTTCAGGACGCGCGGGACAC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	GGGCATTATACTTTAGGCATACCTATTAGGGTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CGCATTATGGTCTGGATAATAGCGCGTTACGAA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ATTTCAAGCCCCGTGTTAAAAAAGCAGTATTGG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TAGCGAAGTCCATGCTTGACCTTGGCCCCGCGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CAGCCGTTCAAAGTAATTATCGTCTACTATAAC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGCGTCGGTCTCTGCGATTTTGCTGATGTATTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AAAGAACAAAGTTTAAGGAATTATGCACTTTTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	GAAAAAGCGGGATTGATTGTATACTGCAAAGATG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCTTTTTTCCTCCCCTCCCCCACTCCGTAACAT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ATAGCTTTCTGCCATGGCTCTGAACCAGTCTCCC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	GAAGTAATCGGTCATCAGAAAAAGTTTGATAG
GTCGCACCCTTCATGGGTGTGTGGATTGAAAC

>NC_015172|2|1|894822-897862|CRT
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	CTGTACTTATGAGAATCTATTGATTATCATCCCAC
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	CCTCATAGGAATCTAGTTTAAATTCAATAAAATC
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	TCTATCATTTTTGGCTCAAAAGCATTTCTGAGC
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	TGAGAAAAAATGATTGTCGGCCTGTCCATCTTT
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	TCGAAAACCCTTGATTGGTAATATTCGTTAAA
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	AGCTAATTCGGCTTGTGATAAGTCATTTCCGAT
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	ACTAATCCCGCCCTCTAAAATCCATAATTCCAA
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	ATACATTTCGATCTGGAACGATAAAATCACGGC
GTCGCACCCCGCAAGGGTGCGTGGATTGAAAC	CAGAAGGGCGTTCGCTATGGCACAGGCCAGGAAA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGACCAGGACCCTTCGCGGCCAGGCTTTCTTCA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AAGAACAGCGCGTCCCAGGAGTACGGAACCGCCAG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGGTCCGCTTTGTCGACAGCGAATGGACGGTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TGGGTTCCAGGATCACGCCGGTCTGTTTGTTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGGTTGACCTTCCAGAAGCGGTCGGCGTAGGGG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CAGGGTGTCGATCGCTCTTTTCGTCCTGGCGGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CGGCCCCGTTCGTCAGCATGGCCGAAGGCGACGA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CGGCCTGACCGGAAGAAAGAAGGTGTTAAACATG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCGGCTGGCGAACGGTCCTGAACGAGTACCGGA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGCTTGCGTCTTCGCTTCCGCCATTCTGGGCCG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCCTGGCGCTGGCTTTCGCGCCCTTCACAAAA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ATCGTGTTTCCCCCTTTTGACAGAAAAAAGGTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TCAGATATGTTTATCTAATTAGATTTTAGTACTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTACCATATCCCAAACAGGAAGAATTATTTTAT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AACATTAAAATCCGAATACCCAATATTTATAGC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CTCATATCTGTTATTGTCATATTATATCGGGCGCC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AAAATTACATTGACATCGAAGCCGATAACTGGGCA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTGAGATTATTGTTTTGTTATGATTATGATTTG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CCGCTGCTTGGCCTTTTGGCTGTCTAAATCGTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ACGTCGAGAGCCAAATCATTCCCGACATCCCCGAC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TCTTTTACCTCCGGCCATTTGCTTTTAGCCATC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TAACTAGGATCGCTGAAAATAATTGGCCTGGCGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCTTTGCTAAGATTTTTTAATTCTGCTGTGTCC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AATCTTAAATTCCTTAAAGGCCTGCAAGATCATG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCTAGCCATTTTTCTATGCACGGCAAACAGGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CTCGGTTTGAATCATTTCAGGACGCGCGGGACAC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	GGGCATTATACTTTAGGCATACCTATTAGGGTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CGCATTATGGTCTGGATAATAGCGCGTTACGAA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ATTTCAAGCCCCGTGTTAAAAAAGCAGTATTGG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TAGCGAAGTCCATGCTTGACCTTGGCCCCGCGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CAGCCGTTCAAAGTAATTATCGTCTACTATAAC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGCGTCGGTCTCTGCGATTTTGCTGATGTATTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AAAGAACAAAGTTTAAGGAATTATGCACTTTTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	GAAAAAGCGGGATTGATTGTATACTGCAAAGATG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCTTTTTTCCTCCCCTCCCCCACTCCGTAACAT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ATAGCTTTCTGCCATGGCTCTGAACCAGTCTCCC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	GAAGTAATCGGTCATCAGAAAAAGTTTGATAG
GTCGCACCCTTCATGGGTGTGTGGATTGAAAC

>NC_015172|2|1|895606-897798|PILER-CR
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TGGGTTCCAGGATCACGCCGGTCTGTTTGTTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGGTTGACCTTCCAGAAGCGGTCGGCGTAGGGG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CAGGGTGTCGATCGCTCTTTTCGTCCTGGCGGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CGGCCCCGTTCGTCAGCATGGCCGAAGGCGACGA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CGGCCTGACCGGAAGAAAGAAGGTGTTAAACATG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCGGCTGGCGAACGGTCCTGAACGAGTACCGGA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGCTTGCGTCTTCGCTTCCGCCATTCTGGGCCG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCCTGGCGCTGGCTTTCGCGCCCTTCACAAAA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ATCGTGTTTCCCCCTTTTGACAGAAAAAAGGTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TCAGATATGTTTATCTAATTAGATTTTAGTACTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTACCATATCCCAAACAGGAAGAATTATTTTAT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AACATTAAAATCCGAATACCCAATATTTATAGC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CTCATATCTGTTATTGTCATATTATATCGGGCGCC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AAAATTACATTGACATCGAAGCCGATAACTGGGCA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTGAGATTATTGTTTTGTTATGATTATGATTTG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CCGCTGCTTGGCCTTTTGGCTGTCTAAATCGTC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ACGTCGAGAGCCAAATCATTCCCGACATCCCCGAC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TCTTTTACCTCCGGCCATTTGCTTTTAGCCATC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TAACTAGGATCGCTGAAAATAATTGGCCTGGCGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCTTTGCTAAGATTTTTTAATTCTGCTGTGTCC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AATCTTAAATTCCTTAAAGGCCTGCAAGATCATG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCTAGCCATTTTTCTATGCACGGCAAACAGGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CTCGGTTTGAATCATTTCAGGACGCGCGGGACAC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	GGGCATTATACTTTAGGCATACCTATTAGGGTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CGCATTATGGTCTGGATAATAGCGCGTTACGAA
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ATTTCAAGCCCCGTGTTAAAAAAGCAGTATTGG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TAGCGAAGTCCATGCTTGACCTTGGCCCCGCGT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	CAGCCGTTCAAAGTAATTATCGTCTACTATAAC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AGCGTCGGTCTCTGCGATTTTGCTGATGTATTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	AAAGAACAAAGTTTAAGGAATTATGCACTTTTT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	GAAAAAGCGGGATTGATTGTATACTGCAAAGATG
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	TTCTTTTTTCCTCCCCTCCCCCACTCCGTAACAT
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC	ATAGCTTTCTGCCATGGCTCTGAACCAGTCTCCC
GTCGCACCCCGCAGGGGTGCGTGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015172.1\|WP_083811183.1\|900879_901071_+\|4Fe-4S-binding-protein	unknown	unknown	gnl\|CDD\|225131
NC_015172.1\|WP_013624117.1\|886483_889000_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_015172.1\|WP_013624127.1\|901630_902401_+\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NC_015172.1\|WP_013624119.1\|889728_891693_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|187887
NC_015172.1\|WP_041445048.1\|905017_906298_+\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|349448
NC_015172.1\|WP_013624122.1\|893322_894354_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_015172.1\|WP_013624129.1\|903063_904746_+\|DUF5301-domain-containing-protein	unknown	unknown	gnl\|CDD\|310280
NC_015172.1\|WP_013624118.1\|889012_889732_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187782
NC_015172.1\|WP_013624125.1\|898579_899857_+\|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase	unknown	unknown	gnl\|CDD\|225428
NC_015172.1\|WP_052298606.1\|883916_884444_+\|hypothetical-protein	unknown	unknown	unknown
NC_015172.1\|WP_013624128.1\|902672_903071_+\|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
NC_015172.1\|WP_013624116.1\|885085_886087_+\|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_015172.1\|WP_013624123.1\|894364_894670_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015172.1\|WP_013624132.1\|907947_908511_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_015172.1\|WP_013624115.1\|883129_883837_+\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|225695
NC_015172.1\|WP_148228067.1\|900676_900970_+\|hypothetical-protein	unknown	unknown	unknown
NC_015172.1\|WP_013624126.1\|900102_900552_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_015172.1\|WP_013624121.1\|892633_893326_+\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NC_015172.1\|WP_013624131.1\|906590_907610_-\|D-alanine--D-alanine-ligase	unknown	unknown	gnl\|CDD\|234948
NC_015172.1\|WP_013624120.1\|891760_892627_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820

Protein	Function_ID	Function_description	E-value
NC_015172.1\|WP_083811183.1\|900879_901071_+\|4Fe-4S-binding-protein	gnl\|CDD\|225131	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion].	9.29191e-10
NC_015172.1\|WP_013624117.1\|886483_889000_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.08354e-52
NC_015172.1\|WP_013624127.1\|901630_902401_+\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.84757e-13
NC_015172.1\|WP_013624119.1\|889728_891693_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	0
NC_015172.1\|WP_013624122.1\|893322_894354_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NC_015172.1\|WP_013624129.1\|903063_904746_+\|DUF5301-domain-containing-protein	gnl\|CDD\|310280	pfam05569, Peptidase_M56, BlaR1 peptidase M56. Production of beta-Lactamase and penicillin-binding protein 2a (which mediate staphylococcal resistance to beta-lactam antibiotics) is regulated by a signal-transducing integral membrane protein and a transcriptional repressor. The signal transducer is a fusion protein with penicillin-binding and zinc metalloprotease domains. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. homologs to this peptidase domain, which corresponds to Merops family M56, are also found in a number of other bacterial genome sequences.	4.22288e-53
NC_015172.1\|WP_013624118.1\|889012_889732_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187782	cd09651, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	7.19921e-94
NC_015172.1\|WP_013624125.1\|898579_899857_+\|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase	gnl\|CDD\|225428	COG2873, MET17, O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism].	0
NC_015172.1\|WP_013624128.1\|902672_903071_+\|BlaI/MecI/CopY-family-transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	6.24444e-30
NC_015172.1\|WP_013624116.1\|885085_886087_+\|transcriptional-regulator	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	8.00105e-53
NC_015172.1\|WP_013624123.1\|894364_894670_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.85751e-34
NC_015172.1\|WP_013624132.1\|907947_908511_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.98997e-13
NC_015172.1\|WP_013624115.1\|883129_883837_+\|N-acetyltransferase	gnl\|CDD\|225695	COG3153, COG3153, Predicted acetyltransferase [General function prediction only].	1.73349e-37
NC_015172.1\|WP_041445048.1\|905017_906298_+\|peptidoglycan-binding-protein	gnl\|CDD\|349448	cd06229, M14_Endopeptidase_I, Peptidase M14 carboxypeptidase family-like domain of Endopeptidase I. Peptidase M14-like domain of Gamma-D-glutamyl-L-diamino acid endopeptidase 1 (also known as Gamma-D-glutamyl-meso-diaminopimelate peptidase I, and Endopeptidase I (ENP1); EC 3.4.19.11). ENP1 is a member of the M14 family of metallocarboxypeptidases (MCPs), and is classified as belonging to subfamily C. However it has an exceptional type of activity of hydrolyzing the gamma-D-Glu-(L)meso-diaminopimelic acid (gamma-D-Glu-Dap) bond of L-Ala-gamma-D-Glu-(L)meso-diaminopimelic acid and L-Ala-gamma-D-Glu-(L)meso-diaminopimelic acid(L)-D-Ala peptides. ENP1 has a different substrate specificity and cellular role than MpaA (MpaA does not belong to this group). ENP1 hydrolyzes the gamma-D-Glu-Dap bond of MurNAc-tripeptide and MurNAc-tetrapeptide, as well as the amide bond of free tripeptide and tetrapeptide. ENP1 is active on spore cortex peptidoglycan, and is produced at stage IV of sporulation in forespore and spore integuments.	1.09103e-114
NC_015172.1\|WP_013624126.1\|900102_900552_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.42868e-14
NC_015172.1\|WP_013624121.1\|892633_893326_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	1.56141e-29
NC_015172.1\|WP_013624131.1\|906590_907610_-\|D-alanine--D-alanine-ligase	gnl\|CDD\|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	1.87586e-107
NC_015172.1\|WP_013624120.1\|891760_892627_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	5.73554e-117

>NC_015172.1|WP_013624123.1|894364_894670_+|CRISPR-associated-endonuclease-Cas2
MMVLITYDVNVTTDSGKKRLYRVAKQCKNFGQRVQNSVFECLVDPTQFTELKHRLESIVDPEKDSLRYYYLGSNWKRRVEHYGANEAYDPEGVLIIDANGK
>NC_015172.1|WP_013624122.1|893322_894354_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MRKLLNTLYVTIPDAYLAREGENVLIKADNEIKFRVPVHNLEGIVCFAFTGASPGLMELCCERGVSLSFLTEYGKFQGRVTGKVSGNILLRKNQYRWTDHDDACLRLAKRFIAAKIINCRAVLHRAVRDHPDTVDKALLVNIMKLMSDLGKKVEKASDLHTLRGVEGQAASLYFSGFNELILAQKSAFQMTGRNRRPPLDRVNALLSFFYTLLAHEAAAALESVGLDPQAGFLHRDRPGRASLALDIMEELRPHFADRLAVTLINRNQIDSDGFVIKESGAVVMDDSTRKEVLTAWQKRKQEEITHPYLEEKVPLGLVPYIQAMLMARHIRGDIEDYPPFIWK
>NC_015172.1|WP_013624121.1|892633_893326_+|CRISPR-associated-protein-Cas4
MSVYEEDDLLLLSGIQHMAFCERQWALIHIEQVWAESSRTLEGKYLHEKADDPFKNETRSDLRIVRAMPIVSYQLGLRGVADVVEFRRVENPPEGIAVKLDKRKGWWQPYPVEYKRGRPKSDDRDAVQLCAQALCLEEMLKISIDCGFLFYGQTKHREQIEFNRVLRTRVEELAGKMQKMFAEGKTPGAKKGKHCSLCSLIEQCQPNLTVRHRSVEAYLKKMLVWEEVNI
>NC_015172.1|WP_013624120.1|891760_892627_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
METLKNKIDFAVIINVKNANPNGDPLNGNRPRVNYDGIGELTDVCIKRKIRNRLMEAGYAIFVQSDDNRIDEYPSLRKRVEGEISKDDWKDEKKFREAVCKKWIDVRAFGQVFAYEGGKKGEGVSIGVRGPVSMHSAFSVAPVLERISSIQITKSVSSEGDGTKRSSDTMGMKHRVDHGVYVFYGSMNPQLASKTGFSDEDAEAIKKVLVNLFENDASSARPEGSMEVYKVYWWKHNCKNGQYSSAKVHGALKVEVKLDVDVPKDIEKDYDITLQPLSELNPEIIPGR
>NC_015172.1|WP_013624119.1|889728_891693_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSWLQKLYQTAENCQSMIGYGSDENEVPLLPICHTTQKAQIEIVIDQDGNFKRARVIPKEEARTIVPCTETSGGRSGRKPETHPLCDKLQYIAGDFVEYGGEVTSGYAKKPREPYEKYTKILSNWCESPYPNTKAQAILKYIKKLNVIKDLIDFQILFVDDNKKLLKSWEEDEESEKNKPDIFKLLPGKINKKNGEVESWQADAFVRWIVEIPNDPQSAVWTDARLFDSWTKYYSSTKESKTLCLVTGKEVMAADQHPAKIRNDGDKAKLISANDTSGFTFRGRFLSAEQACGVGFEVTQKAHNVLRWLINRQGYRRGDQAIVAWATSGKEIPDLMADSLSMLELADMENDSEPVISTVQDLALKLSKKIAGYSVELGSTANVVVLGLESATPGRMAMTFYRELTGSDFLDRLEKWHKMCCWIHGYRSKEIIDSRTGKKRTLHYRFVGAPAPNDIAEAAYGMRVDDRLRKATVERIIPCIIDGRKLPRDLMESAVRRASNRISLEDWDWNKTLSIACALYKKYHEKEDFDMALDEKRNTRDYLYGRLLALADNIEEWAINDSGEKRQTNAARLMQRFADRPYSTWRNLELALGPYKARLGGKSAGRQKLISEVIDMFKPDDFISDKKLSGEFLLGYHSQREALRKKRDEEKQND
>NC_015172.1|WP_013624118.1|889012_889732_+|type-I-C-CRISPR-associated-protein-Cas5
MENKVEFKVYGKYALFTDPLTKIGGEKCSYQIPTYQALKGIMESVYWKPTLIWFIDKIRVIKQIKTQTRSAKPIEYGGGNSLSIYTYLSDVEYQVQAHFEWNLHREDLAKDRNDNKHFFVAKRMIERGGRRDIFLGTRECQGYVEPCRFGEEESFYDNYGELSFDLMFHGFDYPDEIGKDELQARFWRPKMIDGVVEFIRPEQCEIRKFIRPMSARNIESIGLEEEGLLEGYSEEVVKR
>NC_015172.1|WP_013624117.1|886483_889000_+|CRISPR-associated-helicase/endonuclease-Cas3
MEYNKYKDESNPKFIAHHREKDGEKQFLEEHLEEASVLAGKFAKKIGLEKHGELIGLLHDLGKATFEFYQYIGSATGLIDPDEDDYIDASGKKGKIDHSSAGAQVIYNYFSGINKESAFASQILSLIIASHHSGLIDCLSPDGIDNYSRRMKKSDEKTRTKEALTNVNDIIKRKMEKILSDGNFISDFNLKLKSLQEFNDSDDTFMFKAGLLTKFLFSCLVDADRLNTADFEFPERLKLRNQGDYVPWQILIDKLEKHLSDLENKTEIKNEEQKRVNKLRKEISDHCLKFSEQPKGLYQLTVPTGGGKTLSSLRFALNHVNHHEMDRIIYVIPYTSIIDQNAETVRKIMVGEIEQVTDMREVVLEHHSNLTPEEETTRQKLLAENWDAPIVFTTMVQLLETLFGYGTRSGRRMHQLANTVIIFDEIQTLPVQCVYLFNIAVRFLLKTCGSTVILCTATQPLLNSEILGNKALSIGPQQQMISDVRKLFEDLRRVEVFDRCKVGGWTIEEIADLVETELKETGSVLAIVNTKNSASALFQQVRNNPKAKVYHLSTNMCPAHRLQYLQEIKDCLANEQPVICISTQLIEAGVDIDFGSVIRYLAGLDSIAQAAGRCNRNGARPQRGRVFIVNPLVEKLNKLTDIKIGRKKAERILEEFKTDSAQFEEDILGLKAMERYYQYYFYERKEDMSYVVGPKSEAGRLDNLFGLLATNPNSVQEYQRVNSVSPETFLRQSFMTAAKIFQAIDSRTQGVIVPYGEGNRIISELCEVKDLHTQYHLLKEAQRYSVNVYCNQFDELIKQKIMHEVQEGAGIFYLDKQYYSKEYGMSESKVNEMETLTC
>NC_015172.1|WP_013624116.1|885085_886087_+|transcriptional-regulator
MNHTDRTERLLNLIYTIQKSPGIQAKELAEIFGRTSRTIQRDICDLRKYGFFIDSSTGAAGGFRSRGSYFLKPLVFSGEEALAIFVASRVLLEQKGFPFRGDLESALAKISQVIREKDEDFFKSLEPRTSIVVKQIKDYYPWGEVFTEMNRAILDRAMIEITYDSYNSGTVSVRKVNPYHIMFKEGCWYLIAYCHQREEIRIFRVDRIKDLHRTDEQFPSPEDFSLQEYFRESWQMGKGEPVTVKVRFEPPVSRLIRENTWHPAQEIEELEGDRLIYTVRVEGTYEIKQWILSHGAAAECLEPEGLREEIGRELREMAERYALRETPDFSFKI
>NC_015172.1|WP_052298606.1|883916_884444_+|hypothetical-protein
MTIPSAVPSITQILGNPNQGSGGFAVNIPYNHLGIVSIVLLILFMLAGAFLKGGFLGCVLAGVNDHEVRIGTFMAMAKKYFLRFILQSSITFILVIAFVPFFFIPGPLVLFLFIGIIILFFYLMFWDYIIVVENAKLIDAARISCSLVQSNLRKVLSLVIPVSIITALFGIWRMP
>NC_015172.1|WP_013624115.1|883129_883837_+|N-acetyltransferase
MEETKSNHKGNKHVRKIKLRLEQPADYRKVEELTREAFWNHYVPGCNEHYLLHIMRDCGAFIRELDTVAEIDGEIVGNIVYTKGKILGDDGISREVLSFGPVSVLPALKAAGIGSALIEYTLARAKESGHGAVLIYGDPAYYQRFGFISAETFGIGTADNMYAQPLQALELREGTLRGCKGRFFEDAVYDIDEEAAAEFDKTFPDKELQDDLPSQERFRCLLGLRRPRGAGGGKE
>NC_015172.1|WP_013624125.1|898579_899857_+|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase
MSGRIETKCIHEGWKPEKGAPRQLPVYQSTTFKYDTSDEMGKLFDLEAEGYFYTRLQNPTNDAVAAKICALEGGAGAMLTSSGQAANFYALFNICEAGDHFIASSAIYGGTYNLFGVTMRKMGIECTFVDQDLPEEELERYFQANTKAVFGETITNPTVSVFDFEKFARLAHRHGVPLIVDNTFATPVNCRPFEWGADIVTHSTTKYMDGHAVGVGGCIVDSGNFDWTAHAEKFPGLTTPDDSYHGLIYAERFGKGAYITKATTQLMRDLGAIQSPQNAFYLNLGLETLHLRMKRHCENALETARFLEKHQKVAWVNYPGLQSSPYHHLAAKYLPDGSCGVLAFGIKGGRERSIQFMDKLKLASIVTHVADSKTCLLHPASHTHRQLTDEQLRKAGVAPDLIRLSVGIEHSEDIIEDLRQALEQI
>NC_015172.1|WP_013624126.1|900102_900552_+|MarR-family-transcriptional-regulator
MNQKLRILDTLIKIQEHSDVFEPKLAGLLDEISLAEVHCIDWIGRLDHPNVTKISEKMGLTRGAISKISKKLLSKGLIETYQEPDNHKEIYFRLTESGRSVYGEHKKLHNEVREEWLSFLEHYSEDEQAVLFRFLTEIGDLLDRKWADQ
>NC_015172.1|WP_148228067.1|900676_900970_+|hypothetical-protein
MVWATHPCFAAPKPDSAAAGLPGSCVMDRLLQKEEGVKCSRISCHLVSKRMEMESRKEIRPLLSAGIRLPLKNAGAATNAKRLARPERSGESVAKRM
>NC_015172.1|WP_083811183.1|900879_901071_+|4Fe-4S-binding-protein
MTPEKCRSCDKCKKACKAGAIRGERGKAYVIDEQKCIKCGTCIKRCRDKAIKKLEMYSGEAKP
>NC_015172.1|WP_013624127.1|901630_902401_+|sulfite-exporter-TauE/SafE-family-protein
MGINMDDFLQLLNLTQMQCIIVMVTAFLVGFSKTGISGVLMLVIPMLASVFGGRDSTGILLPMLLVGDVFAVWSYRRSVNWKKVIAPLPWALIGMVIGAVVGKVISDQIFVILIGIIVLFCLGILLYTEKMGKNFEVPTQTWFYITAGILSGFATMIGNAAGPIFSVYLLALGLQKNHFMGTNAWFFFIINSIKVPVQIFAWHNMGMQLLILTAVVLPVIALGAVLGFFIVKKINEKFFRYLIIGMTALSALRLFM
>NC_015172.1|WP_013624128.1|902672_903071_+|BlaI/MecI/CopY-family-transcriptional-regulator
MNDKIKRLGDAELEMMLVIWDTSEPVTSNYILERLHGRRGWALSTLMTALARLAAKGFVYCDRTTRTNLYSALISAEEYKAKESRSILEKLYGNSLQNLVTSLYDSHTINDADLSELQKLIEKIERRKNNHA
>NC_015172.1|WP_013624129.1|903063_904746_+|DUF5301-domain-containing-protein
MLESLFVTLLEVSGTAGLMILVLKLLSPLFNQFYASKLKYWIWLVLAVRLMIPVNFSIPMTPVEMSIPDRQMNAWTTPAPTQQNPGGTPPVINHPVTEAPPISLTLIEAAMIIWIIGCVVFLSNQIAGYLVLKKKALRWSKAPADPRIVAAVAPASTSVGLTKTITLRISERVAGPMMIGFTQPILFLPHEDYSDTDIAFIMRHELTHCKRHDLWYKLLLVFVNALHWFNPFVYLMFREASADLELSCDDEVIKGVSPELRRAYGETILTEIKRQKNFQTPLSTYFFGGQKRLKSRLQNILNTKKRGNGTVVLVLTVLAITLVSALVACRVSEQGINADQIEEIKISMQDKGLQVSGDHVYPKENRQGIQGIVDILNRASPTAKKSVNDVPPDDRVIKVELLPNKTVYLYQDGEKYYAETPYESVAELTKEAYETILEMFGPIHPFPEDTDKTQFLAALQTMLEQYRSGQPPETGMEHRFDPAPQGLLLPSVNSADDFELTDGSTESLYAAIIRFGENDAYSVRMALNQFSEDGENRWGVTSVYFSGPDTGTDESAAQGR
>NC_015172.1|WP_041445048.1|905017_906298_+|peptidoglycan-binding-protein
MRMLKVGLRGNDVAEVQALLKQRGFDPGPVDGIFGTKTEQAVRRFQNARGLSADGIVGPLTYQALQATSAPSTYTVQPGDSLYLISSRFGISLGALMAANPGVSSYDLQIGQRLNIPAAGGDIVTTTINYTYDVLNWDIWSLKDRYPALGVGVAGQSVLGRNLYYLRLGSGPNQVFFNASHHSLEWITTVLLMKFTENFLKAYTAGTAIRGYRPRDIWNRSSIYIIPMVNPDGIELVLNGLRSGNPYDESLIRWNNGSTNFSRVWQANIRGVDLNHNYDASWQLSKQAEAAYGITGPGPTRYSGPYPESEPESRTVADFTRARDFRLVIAYHSQGEVIYWNYQNMAGAAARNIGERFSAVSGYALDETTGIASYAGYKDWFIERYRRPGYTVEVGSGTNPLPISQFPQIYNANEELLLLASVITAS
>NC_015172.1|WP_013624131.1|906590_907610_-|D-alanine--D-alanine-ligase
MKIIVLAGGLSPERDVSLSSGALISNALIEKGHDVMLLDLYLGINNKHIEPAYINLKSNKTFSYLVPPEEPDLDAIKASVNNRGSLIGDGIIDLCKEADVVFLALHGSIGENGKLQAVLDINGIKYTGTGYVGSLLAMDKDLSKKLILSNNILTPHWKYVDLQTDTDFDDINYPCVVKPCSCGSSVGVTMVETPSELNSAIEFAKKYENSVIIEEKIVGREFSVGILNGEALPVIEIKPLIGFYDYKNKYQKGLTGEICPANISNEIRYLLQNSAVKVHNLLRLGFYSRIDFILDQSNNAYCLEANTLPGMTPTSLLPQEALANDITYSDLCEKIAFAI
>NC_015172.1|WP_013624132.1|907947_908511_-|TetR/AcrR-family-transcriptional-regulator
MTKKMNPLIIKSQKWLVDALLSLMKQKAFSQITIREIAEKAELDRRTFYRHFSSKEDILNHYIDNLYKEYLSNLSKEPELTIYSISKIYFEFWENHLDFLLIIIQNHLQSFLLSKYNEYLPQIYNALESGIPLSTNSIYFQYALAFKSGGFWNILFEWAKNGAMQKPHEMANIVFKLVGNNLMESAD

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Crispr_ID: NC_015172_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015172_3

1392092-1393715

Unclear

Consensus_repeat	Method
CTTGTAATTTAACCAGAATGGAATGTAAA	PILER-CR
CTTGTAATTTAACCAGAATGGAATGTAAAG	CRISPRCasFinder
CTTGTAATTTAACCAGAATGGAATGTAAA	CRT

24 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of NC_015172_3

>merge|NC_015172|3|1392092-1393715|PILER-CR,CRISPRCasFinder,CRT
CTTGTAATTTAACCAGAATGGAATGTAAAGAATAGCAAACTTACAGGTATTATTCTCTCGGCCGACCTTGTAATTTAACCAGAATGGAATGTAAAGTCTTTATGTTCACATTACACTGAAGAGTCCGTCTTGCTTGTAATTTAACCAGAATGGAATGTAAAGTCAGCATAAATAACTAAATTATCCACGTTATCCTCCTTGTAATTTAACCAGAATGGAATGTAAAGGCCTCCACATTGTACGCCTCCCCTACCTCCGAGGCCCTTGTAATTTAACCAGAATGGAATGTAAAGGAGCCAGCATTGGGCCGCTTGTAATGCCGCCCGTGGCCCTTGTAATTTAACCAGAATGGAATGTAAAGATCAACATCCTTGATAGAATCAATGACCAAGAAACTCCTTGTAATTTAACCAGAATGGAATGTAAAGTTGATTGTCAATGTCGATACGGTATATATCCATACAGCTTGTAATTTAACCAGAATGGAATGTAAAGTTGATTGTCAATGTCGATACGGTATATATCCATACAGCTTGTAATTTAACCAGAATGGAATGTAAAGTTGATTGTCAATGTCGATACGGTATATATCCATACAGCTTGTAATTTAACCAGAATGGAATGTAAAGTGGTTTCAAAGTACGAGAATAATATTCATACTCCCAACTTGTAATTTAACCAGAATGGAATGTAAAGGATTTTGATTTCATTATAGCATCGTTCCGTATAAAACTTGTAATTTAACCAGAATGGAATGTAAAGGGCCTGTCCCCGGAGATTGAAATTGATGTCGATGACACCTTGTAATTTAACCAGAATGGAATGTAAAGACTACTACTGAAGAAGCCTTAGCCATCTTTCCGGATTCTTGTAATTTAACCAGAATGGAATGTAAAGTAAATTATGGCCGCGCCGTCAACCTTGAAATAGTATGACTTGTAATTTAACCAGAATGGAATGTAAAGTTCGCTGTTATCTATTCGCTTGCCGCGAAAAAGTCTTGTAATTTAACCAGAATGGAATGTAAAGCCTGCTGAAGCTTATAGGCCATGATATATGACCAGCTTGTAATTTAACCAGAATGGAATGTAAATTTTCTAACTCCAACGCCTGCTCATTGCCCTCGGCATCCTTGTAATTTAACCAGAATGGAATGTAAATCGATCACATCAAGCACGGACTGACAGGTCTTATACCCTTGTAATTTAACCAGAATGGAATGTAAATTAAGTTACTTATTGATAGTCAGTCTGAAATGGCAAGCTTGTAATTTAACCAGAATGGAATGTAAATAGGTGATCAGCATCAAGGGTGATCAGGCTGCGGGTACTTGTAATTTAACCAGAATGGAATGTAAACGCAAATGTGAAATACTGTGTCCTTGATATCGACTGGCTTGTAATTTAACCAGAATGGAATGTAAACGGACGATACCGCTTAAACGAGATAACCCAGACCCAGCTTGTAATTTAGCCAGAATGGAATGTAAACTCCTATGGCTTCCTGTAATTGCCCTTCCAATTCTTTCTTGTAATTTAGCCAGAATGGAATGTAAACTTGATCACGTTGTCTTCAGAGATATTTACAAACTGCCTTGTAATTTAGCCAGAATGGAATGTAAACG

>NC_015172|3|2|1392092-1393713|PILER-CR
CTTGTAATTTAACCAGAATGGAATGTAAA	GAATAGCAAACTTACAGGTATTATTCTCTCGGCCGAC
CTTGTAATTTAACCAGAATGGAATGTAAA	GTCTTTATGTTCACATTACACTGAAGAGTCCGTCTTG
CTTGTAATTTAACCAGAATGGAATGTAAA	GTCAGCATAAATAACTAAATTATCCACGTTATCCTC
CTTGTAATTTAACCAGAATGGAATGTAAA	GGCCTCCACATTGTACGCCTCCCCTACCTCCGAGGCC
CTTGTAATTTAACCAGAATGGAATGTAAA	GGAGCCAGCATTGGGCCGCTTGTAATGCCGCCCGTGGCC
CTTGTAATTTAACCAGAATGGAATGTAAA	GATCAACATCCTTGATAGAATCAATGACCAAGAAACTC
CTTGTAATTTAACCAGAATGGAATGTAAA	GTTGATTGTCAATGTCGATACGGTATATATCCATACAG
CTTGTAATTTAACCAGAATGGAATGTAAA	GTTGATTGTCAATGTCGATACGGTATATATCCATACAG
CTTGTAATTTAACCAGAATGGAATGTAAA	GTTGATTGTCAATGTCGATACGGTATATATCCATACAG
CTTGTAATTTAACCAGAATGGAATGTAAA	GTGGTTTCAAAGTACGAGAATAATATTCATACTCCCAA
CTTGTAATTTAACCAGAATGGAATGTAAA	GGATTTTGATTTCATTATAGCATCGTTCCGTATAAAA
CTTGTAATTTAACCAGAATGGAATGTAAA	GGGCCTGTCCCCGGAGATTGAAATTGATGTCGATGACAC
CTTGTAATTTAACCAGAATGGAATGTAAA	GACTACTACTGAAGAAGCCTTAGCCATCTTTCCGGATT
CTTGTAATTTAACCAGAATGGAATGTAAA	GTAAATTATGGCCGCGCCGTCAACCTTGAAATAGTATGA
CTTGTAATTTAACCAGAATGGAATGTAAA	GTTCGCTGTTATCTATTCGCTTGCCGCGAAAAAGT
CTTGTAATTTAACCAGAATGGAATGTAAA	GCCTGCTGAAGCTTATAGGCCATGATATATGACCAG
CTTGTAATTTAACCAGAATGGAATGTAAA	TTTTCTAACTCCAACGCCTGCTCATTGCCCTCGGCATC
CTTGTAATTTAACCAGAATGGAATGTAAA	TCGATCACATCAAGCACGGACTGACAGGTCTTATACC
CTTGTAATTTAACCAGAATGGAATGTAAA	TTAAGTTACTTATTGATAGTCAGTCTGAAATGGCAAG
CTTGTAATTTAACCAGAATGGAATGTAAA	TAGGTGATCAGCATCAAGGGTGATCAGGCTGCGGGTA
CTTGTAATTTAACCAGAATGGAATGTAAA	CGCAAATGTGAAATACTGTGTCCTTGATATCGACTGG
CTTGTAATTTAACCAGAATGGAATGTAAA	CGGACGATACCGCTTAAACGAGATAACCCAGACCCAG
CTTGTAATTTAGCCAGAATGGAATGTAAA	CTCCTATGGCTTCCTGTAATTGCCCTTCCAATTCTTT
CTTGTAATTTAGCCAGAATGGAATGTAAA	CTTGATCACGTTGTCTTCAGAGATATTTACAAACTGC
CTTGTAATTTAGCCAGAATGGAATGTAAA

>NC_015172|3|3|1392092-1393715|CRISPRCasFinder
CTTGTAATTTAACCAGAATGGAATGTAAAG	AATAGCAAACTTACAGGTATTATTCTCTCGGCCGAC
CTTGTAATTTAACCAGAATGGAATGTAAAG	TCTTTATGTTCACATTACACTGAAGAGTCCGTCTTG
CTTGTAATTTAACCAGAATGGAATGTAAAG	TCAGCATAAATAACTAAATTATCCACGTTATCCTC
CTTGTAATTTAACCAGAATGGAATGTAAAG	GCCTCCACATTGTACGCCTCCCCTACCTCCGAGGCC
CTTGTAATTTAACCAGAATGGAATGTAAAG	GAGCCAGCATTGGGCCGCTTGTAATGCCGCCCGTGGCC
CTTGTAATTTAACCAGAATGGAATGTAAAG	ATCAACATCCTTGATAGAATCAATGACCAAGAAACTC
CTTGTAATTTAACCAGAATGGAATGTAAAG	TTGATTGTCAATGTCGATACGGTATATATCCATACAG
CTTGTAATTTAACCAGAATGGAATGTAAAG	TTGATTGTCAATGTCGATACGGTATATATCCATACAG
CTTGTAATTTAACCAGAATGGAATGTAAAG	TTGATTGTCAATGTCGATACGGTATATATCCATACAG
CTTGTAATTTAACCAGAATGGAATGTAAAG	TGGTTTCAAAGTACGAGAATAATATTCATACTCCCAA
CTTGTAATTTAACCAGAATGGAATGTAAAG	GATTTTGATTTCATTATAGCATCGTTCCGTATAAAA
CTTGTAATTTAACCAGAATGGAATGTAAAG	GGCCTGTCCCCGGAGATTGAAATTGATGTCGATGACAC
CTTGTAATTTAACCAGAATGGAATGTAAAG	ACTACTACTGAAGAAGCCTTAGCCATCTTTCCGGATT
CTTGTAATTTAACCAGAATGGAATGTAAAG	TAAATTATGGCCGCGCCGTCAACCTTGAAATAGTATGA
CTTGTAATTTAACCAGAATGGAATGTAAAG	TTCGCTGTTATCTATTCGCTTGCCGCGAAAAAGT
CTTGTAATTTAACCAGAATGGAATGTAAAG	CCTGCTGAAGCTTATAGGCCATGATATATGACCAG
CTTGTAATTTAACCAGAATGGAATGTAAAT	TTTCTAACTCCAACGCCTGCTCATTGCCCTCGGCATC
CTTGTAATTTAACCAGAATGGAATGTAAAT	CGATCACATCAAGCACGGACTGACAGGTCTTATACC
CTTGTAATTTAACCAGAATGGAATGTAAAT	TAAGTTACTTATTGATAGTCAGTCTGAAATGGCAAG
CTTGTAATTTAACCAGAATGGAATGTAAAT	AGGTGATCAGCATCAAGGGTGATCAGGCTGCGGGTA
CTTGTAATTTAACCAGAATGGAATGTAAAC	GCAAATGTGAAATACTGTGTCCTTGATATCGACTGG
CTTGTAATTTAACCAGAATGGAATGTAAAC	GGACGATACCGCTTAAACGAGATAACCCAGACCCAG
CTTGTAATTTAGCCAGAATGGAATGTAAAC	TCCTATGGCTTCCTGTAATTGCCCTTCCAATTCTTT
CTTGTAATTTAGCCAGAATGGAATGTAAAC	TTGATCACGTTGTCTTCAGAGATATTTACAAACTGC
CTTGTAATTTAGCCAGAATGGAATGTAAACG

>NC_015172|3|2|1392092-1393713|CRT
CTTGTAATTTAACCAGAATGGAATGTAAA	GAATAGCAAACTTACAGGTATTATTCTCTCGGCCGAC
CTTGTAATTTAACCAGAATGGAATGTAAA	GTCTTTATGTTCACATTACACTGAAGAGTCCGTCTTG
CTTGTAATTTAACCAGAATGGAATGTAAA	GTCAGCATAAATAACTAAATTATCCACGTTATCCTC
CTTGTAATTTAACCAGAATGGAATGTAAA	GGCCTCCACATTGTACGCCTCCCCTACCTCCGAGGCC
CTTGTAATTTAACCAGAATGGAATGTAAA	GGAGCCAGCATTGGGCCGCTTGTAATGCCGCCCGTGGCC
CTTGTAATTTAACCAGAATGGAATGTAAA	GATCAACATCCTTGATAGAATCAATGACCAAGAAACTC
CTTGTAATTTAACCAGAATGGAATGTAAA	GTTGATTGTCAATGTCGATACGGTATATATCCATACAG
CTTGTAATTTAACCAGAATGGAATGTAAA	GTTGATTGTCAATGTCGATACGGTATATATCCATACAG
CTTGTAATTTAACCAGAATGGAATGTAAA	GTTGATTGTCAATGTCGATACGGTATATATCCATACAG
CTTGTAATTTAACCAGAATGGAATGTAAA	GTGGTTTCAAAGTACGAGAATAATATTCATACTCCCAA
CTTGTAATTTAACCAGAATGGAATGTAAA	GGATTTTGATTTCATTATAGCATCGTTCCGTATAAAA
CTTGTAATTTAACCAGAATGGAATGTAAA	GGGCCTGTCCCCGGAGATTGAAATTGATGTCGATGACAC
CTTGTAATTTAACCAGAATGGAATGTAAA	GACTACTACTGAAGAAGCCTTAGCCATCTTTCCGGATT
CTTGTAATTTAACCAGAATGGAATGTAAA	GTAAATTATGGCCGCGCCGTCAACCTTGAAATAGTATGA
CTTGTAATTTAACCAGAATGGAATGTAAA	GTTCGCTGTTATCTATTCGCTTGCCGCGAAAAAGT
CTTGTAATTTAACCAGAATGGAATGTAAA	GCCTGCTGAAGCTTATAGGCCATGATATATGACCAG
CTTGTAATTTAACCAGAATGGAATGTAAA	TTTTCTAACTCCAACGCCTGCTCATTGCCCTCGGCATC
CTTGTAATTTAACCAGAATGGAATGTAAA	TCGATCACATCAAGCACGGACTGACAGGTCTTATACC
CTTGTAATTTAACCAGAATGGAATGTAAA	TTAAGTTACTTATTGATAGTCAGTCTGAAATGGCAAG
CTTGTAATTTAACCAGAATGGAATGTAAA	TAGGTGATCAGCATCAAGGGTGATCAGGCTGCGGGTA
CTTGTAATTTAACCAGAATGGAATGTAAA	CGCAAATGTGAAATACTGTGTCCTTGATATCGACTGG
CTTGTAATTTAACCAGAATGGAATGTAAA	CGGACGATACCGCTTAAACGAGATAACCCAGACCCAG
CTTGTAATTTAGCCAGAATGGAATGTAAA	CTCCTATGGCTTCCTGTAATTGCCCTTCCAATTCTTT
CTTGTAATTTAGCCAGAATGGAATGTAAA	CTTGATCACGTTGTCTTCAGAGATATTTACAAACTGC
CTTGTAATTTAGCCAGAATGGAATGTAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015172.1\|WP_013624559.1\|1384237_1385950_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09754_cas8b2_CAS-I-B	gnl\|CDD\|187884
NC_015172.1\|WP_041445151.1\|1390112_1390601_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_015172.1\|WP_013624566.1\|1393802_1394090_+\|transposase	unknown	unknown	gnl\|CDD\|225511
NC_015172.1\|WP_013624569.1\|1396704_1398786_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|223650
NC_015172.1\|WP_041445147.1\|1387688_1390058_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
NC_015172.1\|WP_013624571.1\|1399803_1400673_+\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|275263
NC_015172.1\|WP_041445156.1\|1396024_1396699_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_015172.1\|WP_013624565.1\|1391611_1391890_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015172.1\|WP_013624567.1\|1395005_1396028_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_015172.1\|WP_013624556.1\|1381167_1381935_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223673
NC_015172.1\|WP_013624557.1\|1381961_1383008_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|378117
NC_015172.1\|WP_013624558.1\|1383493_1384222_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_015172.1\|WP_013624561.1\|1386805_1387564_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|273860
NC_015172.1\|WP_013624570.1\|1398775_1399555_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_015172.1\|WP_013624575.1\|1402373_1402706_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|274102
NC_015172.1\|WP_013624560.1\|1385946_1386819_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|274215
NC_015172.1\|WP_013624572.1\|1400871_1401414_+\|glutathione-peroxidase	unknown	unknown	gnl\|CDD\|223463
NC_015172.1\|WP_013624573.1\|1401428_1401872_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_015172.1\|WP_013624564.1\|1390612_1391605_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_015172.1\|WP_148228096.1\|1394047_1394551_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853

Protein	Function_ID	Function_description	E-value
NC_015172.1\|WP_013624559.1\|1384237_1385950_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187884	cd09754, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	6.19999e-21
NC_015172.1\|WP_041445151.1\|1390112_1390601_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.36731e-60
NC_015172.1\|WP_013624566.1\|1393802_1394090_+\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.603e-10
NC_015172.1\|WP_013624569.1\|1396704_1398786_-\|FtsX-like-permease-family-protein	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	1.44648e-06
NC_015172.1\|WP_041445147.1\|1387688_1390058_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	2.17665e-56
NC_015172.1\|WP_013624571.1\|1399803_1400673_+\|radical-SAM-protein	gnl\|CDD\|275263	TIGR04470, hypothetical_protein_ALIPUT_00462, radical SAM mobile pair protein B. Members of this family are the downstream member (B) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.	6.70797e-21
NC_015172.1\|WP_041445156.1\|1396024_1396699_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.05215e-58
NC_015172.1\|WP_013624565.1\|1391611_1391890_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.48974e-28
NC_015172.1\|WP_013624567.1\|1395005_1396028_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.086e-30
NC_015172.1\|WP_013624556.1\|1381167_1381935_+\|ABC-transporter-permease-subunit	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	9.04778e-41
NC_015172.1\|WP_013624557.1\|1381961_1383008_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|378117	pfam09084, NMT1, NMT1/THI5 like. This family contains the NMT1 and THI5 proteins. These proteins are proposed to be required for the biosynthesis of the pyrimidine moiety of thiamine. They are regulated by thiamine. The protein adopts a fold related to the periplasmic binding protein (PBP) family. Both pyridoxal-5'-phosphate (PLP) and an iron atom are bound to the protein suggesting numerous residues of the active site necessary for HMP-P biosynthesis. The yeast protein is a dimer and, although exceptionally using PLP as a substrate, has notable similarities with enzymes dependent on this molecule as a cofactor.	1.77889e-42
NC_015172.1\|WP_013624558.1\|1383493_1384222_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	2.14143e-23
NC_015172.1\|WP_013624561.1\|1386805_1387564_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	1.49658e-23
NC_015172.1\|WP_013624570.1\|1398775_1399555_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.06844e-100
NC_015172.1\|WP_013624575.1\|1402373_1402706_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	6.55274e-18
NC_015172.1\|WP_013624560.1\|1385946_1386819_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	6.72318e-56
NC_015172.1\|WP_013624572.1\|1400871_1401414_+\|glutathione-peroxidase	gnl\|CDD\|223463	COG0386, BtuE, Glutathione peroxidase [Posttranslational modification, protein turnover, chaperones].	7.90356e-89
NC_015172.1\|WP_013624573.1\|1401428_1401872_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.8115e-22
NC_015172.1\|WP_013624564.1\|1390612_1391605_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	8.00744e-164
NC_015172.1\|WP_148228096.1\|1394047_1394551_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.84918e-31

>NC_015172.1|WP_013624565.1|1391611_1391890_+|CRISPR-associated-endonuclease-Cas2
MYIILVYDIEMDEGGARASRRIFKTCKKYLTHVQKSVFEGDITPALLKKLQAELSAYIREDRDSVLVFKSREERWLQKEFWGKEDDKTSNFF
>NC_015172.1|WP_013624564.1|1390612_1391605_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MAESFYLFSNGELQRKDNVLRMVAPDGRFKDIKVEMTRDIYLFGEVSLNTKCLNYAGQLSIPIHIFNYYGFYTGSFYPKEENVSGKLLIGQVQHYTDPRQRLEIARAFIEAASYNMLRNLRYYNERSRDLEACMAEIRGLRKGIETAKDIQELMGVEGSIRKAYYGSWKEIINQEIDFEKRVKRPPDNMINALISFVNSLVYVTCLTEIYKTQLHPAVSYLHSAGERRFSLCLDIAEVFKPLIADRLIFSMLNKKMLTEKDFERESNFCYLKEAGRKRLLEQYDEDLNRTIRHKGLNKNVSYRYLIRLECYKLIKHLMGDKQYEGFMIWW
>NC_015172.1|WP_041445151.1|1390112_1390601_+|CRISPR-associated-protein-Cas4
MHITGTMFYYYFVCRRKLWCFSQHITLENESERVLLGKILDDMAYGREHKHIMIDETVNVDFIKDWKILHEIKKSKSIEEASIWQVKYYLYFLNQRGIKIEKGILDYPKIKEREEIRLEPGDEEKIKRILQDIEEIVSQEKMPPPVNAKICKSCAYYEYCYV
>NC_015172.1|WP_041445147.1|1387688_1390058_+|CRISPR-associated-helicase/endonuclease-Cas3
MDESALAKSQPKEDIQTHTDGLLCNLNILKELYPNLFADWDKLYELLRLACLYHDMGKLYPRFQYCIARRIPYDGIPHGLLSLAFIDWKRLRQEKGLNNDDLKLLYQAVAYHHDRKMPMGNKEIEAEFPKLREGWERFEYSELPWKGEIQKVINQRYFGVGKRIGKRDQDLFPRFIKLEGLLIRLDYAASAHVKVEHPNDFLAQDMEGLIERWRKNGIGTKWNDLQLYMSQNRDKNVIAIAQTGMGKTEAGLLWLGNAKGFFTLPLKSAINAIYQRIIDEIVMEKKDERVGLLHSDTYTQYLQLKEESAKGKETKEEEEDIPADLYYARTRQLSLPLTVCTLDQLFDFVFLYWGFERKLATLAYAKIIIDEVQMYSPELMAYLILGLRYITGMGGRFAILTATLPAFFIDLLREEKIPFAPRRTFTDGRIRHSLKVIAKAISGEDIVELSRQYPGKKILVICNTVKSAVNLYRQLRWDQDLQEVKLVDVNGKEGDPSEDRDGEREASGVNLLHSCFIKRDRREKERLILKMGEKDSNQSGIWIATQIVEASLDIDFDLLFTELSDLNGLFQRMGRCYRKRELKGTPYNCFVFTGGSKPCSGVGVFIDQEIHRLSQAALAETDGILREAQKVEMIEKLYTKENLPEYYEHIKKDLAYADCWSVGEIKASKAKEKFRDIDNVAVIPRQVYETYRQEIAQAQSILQMDYSGMTEEQIRELKESKAKARNAIMDFTVDISRSWYQDIETDQILELNRYERVPIVKGDYNSQVGMIRPALKKNAEFTDFSSRSF
>NC_015172.1|WP_013624561.1|1386805_1387564_+|type-I-B-CRISPR-associated-protein-Cas5
MKAVRVRLHQDMVNYKKPTSFQLKETYPLPPHSTVIGMVHSLCGYTEYQPMQVSVQGKYFSRVNDLYTRYEFKNAMKYEAARHQLQAGEYGINQGVATAELLVDVELLLHIMPEDQEKVEEIHQALKNPKEYPSLGRREDLATFEEVKVVELSLTELEEPVDAPDDYYAYIPLSLLEDESVQLLHHNRVMGDRQPGTRYRLTKDYELVDYGTKKAPKRFRRWNKVDVIYGVPTALIEGKVTLDEDGLVAYLV
>NC_015172.1|WP_013624560.1|1385946_1386819_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKSKGLTLTIIFQAESANYGESVGNVAALKKISRDRGDQYTYISRQALRYNIAEQLGEDLAPVKAEGSGEKKVIQFSEEATIEHYPEIDFFGYLKTEKGTGGKKRSAKVRLSHAISLEPFHGDLDFLTNKGQADKIKENMNIAQAEIHRSYYRYTVTADLDQIGEDEVYDISLPGAERARRVKKLLDTLAFLYRDIRGRREDLKPLFAIGGVYDIKNPVFQNVVDVKNNTVNIAEIEGVLYDNIKEDTYCGVVENSFVNTGALKETLGASSMPAFFTKLKEKVDQYYEGR
>NC_015172.1|WP_013624559.1|1384237_1385950_+|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MEEEILRLRLGDWQWNGAVIGFIRIVGRENVLFENESIKFSSKLLENFEEKYFAYFIKAYEKTLSWYKIVSFKEWLEAQEDDEFGTFVLKDLNALNEQIKTVKSLIKSNSYKAAYELMALGEDILVWEKELVSIKEPKSEQAFAADKPELIAKVRETFSTLRKIISYCESPEGKRYIRAKNIIYTVIKNAWNGVSFLNPQTKEKDVYLDYKAHFVDGAIAYLKQNKDKFKYHCFICDEPIKDMSLDLSFMNATGFDVARKSSHVWDFQNDIAVCPLCKLIYSCLPAGFTYVYDRGIYININTSVEDAYEVNYKIHHEVLRKEGNLRSIYPVLIGALHEQENAGASYELADIQVVRYEREAYRFNILSRKMLQLIFDSKDRLDSLINTSFAENKLTVRIYDEAISRIFNNQNLFTLIHRMLYDLLSDPSKCRFNGAHITHLLRINQRIYQTLGGMKMGCEDKDNALVREARTAGEQLKRYYYGKNAQHKLPGICYRLLNALKTSNQEMFLDVTLNCYLYVGFPVQRVHTDSLGQEKDFSTVGYAFVAALIDNSKSEDKGSSPVGEMEEEKK
>NC_015172.1|WP_013624558.1|1383493_1384222_+|CRISPR-associated-endoribonuclease-Cas6
MRIKVELETKEETLPLNYREKFLSYLKKIFEDHNRDIYQALYSSGANYKPLCSAIYFRPEVEIVKTGITLKSKRFVATFTTRDVMMGVHLINALLSRRNHWAPLADTGNQLKITAVTKVREHEMTDTAAFRILSPVVVRDHDQKEGRDWYLTFEDKLFEAVWKRNLKSELRTVLGRDAGHDVDGLNIKPIQLRKTVVLCYSIYLPCTIGTFALEGEPYLLDYLYKSGLGSKRSLGFGCLDIL
>NC_015172.1|WP_013624557.1|1381961_1383008_+|ABC-transporter-substrate-binding-protein
MGKRKVLTGLLVVLLLAVLVISGCSSSPQASSDQGAQASGKLDKMTLQLKWLPQSQFMGYYVAQAKGYYKEQGIDLQILPGGSDIIPEQQVYNGVADVGVTWVSSLMKYQSQGWDLVHVGQIFQKSALLLVSKTSKGINSPADLKGKKVGSWFGGNEYEIYALLEANGLNKEKDLKLVQQDYTMNQLLNDQLDAASAMTYNEYGLLLEAGMKESDLHVIDMNDAKVAMLEDCLFVKSDWIAKNADLYQRFLKASIKGWQDACADPAVAGKTVYDADKSVSLDHQVYMAKEVAKLVEPQGFDPAKIGYTDMNAIKQTGDLAHKYGLLTKPAVISEDTFASKYWQQATGK
>NC_015172.1|WP_013624556.1|1381167_1381935_+|ABC-transporter-permease-subunit
MKIDWKNLLWPAAFGIIFILAWQLGLFHKVLNLKPFQLPIPSEIVSTLWKNLPKALSDCGVTISGAIVGMVLGSLIGFMIAAIATFFPKWGYGGMILITAFNAVPIVALSPIMNLWFSTGMGQKIGVVTVVCMAAMAINAYGGLNNLKPFSLDLMHSVAADKWTIFKKLRLPNSLPYLFTAAKINIAASIIAAIISEYFAASTSGLGFGIKDNLRKAEMAMGWSYIVVASLAGVILYCIILLVERDAIKWHASQK
>NC_015172.1|WP_013624566.1|1393802_1394090_+|transposase
MAKNFDQAYKLEICKRVVENRESVTAVAREVGIYENTVYGWVARYRQNSSKPFVGSGHVKAEDEELKRLAKENKELREEIEILKKAAAYFAKNQK
>NC_015172.1|WP_148228096.1|1394047_1394551_+|IS3-family-transposase
MKKGGSLLREKPEIEKYKFIKAESAKYKIAKLCRILHVSRSTYYVWDKPPESKRSIRRKELIEAVKQNFYENKMIPGSLKIAENLSKPEAPVNRKLVAKIMKENGLKSKVVKKYKATTNSNHKLPVAENILNREFTAEKPNQKWVSDITYVPTDEGWLYVAGILDLF
>NC_015172.1|WP_013624567.1|1395005_1396028_-|HAMP-domain-containing-histidine-kinase
MKRRDMSLKAEKQWLNLLLFTDLFFIFLVWLAGPDTFGGLIVIILLFTAVIVLAGYWLDRIRQKNQMEVLQSFLSSPDEETEQRLFAILDASWHPMIRMASARLREQSQALSDKQLELQSYQEFIEAWTHQIKTPLSLATLILANHREEMSSYVYHRMEHVRCTVNSDVERILYYARLQADHADDQFAKMSLSDCVQECLENFRAISGEKNIDVQLNLKPLQVVSDKKVLAFMLSQLFSNAFKYSAPDNGVVRVVSWPDTADDGKIHLAVRDNGKGVPPEDLPFLFDKGFTGSCPERQNATGMGLYLVKKYAEALSVEVKIEPISISGQGFGIELIFPQV
>NC_015172.1|WP_041445156.1|1396024_1396699_-|response-regulator-transcription-factor
MPRIMVIEDDIYLREELVHTFIKKGYSVLSISSFDAPEEEILDSNPDLALLDLNLPGSSGFELCKRLKARASFPILVLTARDTLSDELYALELGADDFLTKPCHSDRLIARAERLLQTYGKVRNLVQAGGLVLDLDTYKVIWQNAHVVLSDTEGKFLRVLLEQYPDVVSKQRLLVELWGGEAYVDENILQVNVTRLRKSLAAIGLREMIQTERGQGYRLEVRKS
>NC_015172.1|WP_013624569.1|1396704_1398786_-|FtsX-like-permease-family-protein
MFFEQIRRNAAKNRKNNGLFFGSLIVAIIAFYTLLSLGDQDVMRFLKTMESDAVHKLMLLIPVIYLISLFFVFFLVYFSYRYQMDNRKKEFGLCLMLGMKRSKLFAMLMSEAVWNSLVSILLGLPLALLLTEGISLTTAKLVGLGIIGHKISFSIPAVLGTIAGFIAVQLIAMLFLSLEFSRKQPLELLRSDCAQKQVSLSGKKGGLCFVFGLIFLILAYVAGIRLLKSFDPQIVALIFILGGSGTFLLYRGLGVFIGHHIRRKSPMRSGLFTFTSRQIQENVLHQYKALAVSSLLLLLALACLSFGIGVASGRGSAETRTADFSIRGSEQEVRAVLDSEASKPMISVYYPMFLSSMETNIYDQTGAVLQSKPNAHEFSWDGLQAALAKLPATDLRNNIMKNFSDRSAPNLISESSYNDLLQAIGKKPLRLEKDQAALYTSIPDSSEFIGVLDSALKSGAYIEVDGRKYELLPGIYQDNVVADRAITLYSGLIVSDENYRNWASDRSEVFCWNVVLSPKVIEEKGLMQAIQLMEQHLAGTGLEYESYISGIGRNLFYTVAASYLTIYLGILFMVIANTVIGLKYLMQQRANQRRYLTLLMFGAGIKDLCKSAKEQIQLFFALALGIAVLNSVFAIWSMFTSFLKLPAETPFAKVVLLAGTAFSLFVVIEFIYISIVEQTSKREIQALRVTDGG
>NC_015172.1|WP_013624570.1|1398775_1399555_-|ABC-transporter-ATP-binding-protein
MNPKRILRVEQITKSYGKGDNVTEALKGISFDVLEGEFLGIMGASGSGKTTLLNCIATMIKPTSGKILLQSSDISSFKGTQLADYRGREIGYLFQEFELLDNLTARENIILPLSLHHVTGRQAEPELQELADRLDIKGVLDKFPAQMSGGQKQRVAAARALISKPSIVLADEPTGALDSKNSKILMDKLSAINKDQQKTILLVTHNALAASYCSRILFIQDGRLFHELRKNIETETPDRFYGRIVTVMAQLGGGSANVL
>NC_015172.1|WP_013624571.1|1399803_1400673_+|radical-SAM-protein
MHDKEVKGILSAKNGMNLYRGCTHGCIYCDSRSRCYQMDHDFEDVEIKRNAPELLEAALRRKRRRCMITTGSMCDPYLPLEKKEKLTRCCLELIDSYGFGFSVITKSHLVLRDLDLLKRINRKTKCVVQMTLTTVDEDLCRVLEPKVCTTAKRAEVLNILRDEGIPTVVWLSPILPFINDTEANLRGILNRCFEAKVKGVICFGMGVTLREGDREYFYKKLDEHFPGMKQRYIETFGNRYSCDSPNQTNLMKIFREQCQRQGVLHSPDAVFTYLNEFEDKQSGEQMTLF
>NC_015172.1|WP_013624572.1|1400871_1401414_+|glutathione-peroxidase
MSVYDYEYTSIENRPVQMSEYQGQVVLIVNTASKCGFTPQYKGLEELYRRYRDQGFTVIGFPCNQFMEQEKGSNEQISEFCSVRYGVTFPLSQKVDVRGETAIPLYQYLTSQKGFEGLGKGIKAKALELTLKARYKDGFADEQIKWNFTKFLIDRNGKVVSRYEPIVEPKDIASDIEKLL
>NC_015172.1|WP_013624573.1|1401428_1401872_+|MarR-family-transcriptional-regulator
MDNQILKLENQLCFPLYAAAKEVVNRYKPFLDEIELTYTQYIAMMVLWEYKSIGVKELGRRLYLDSGTLTPLLKRLEGKGLVRRERSREDERAVKITITEAGEKLQEKASGIPQQMRKCLPLSEEEAGMLYTLLYQLLEGSHREGQA
>NC_015172.1|WP_013624575.1|1402373_1402706_-|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MSCDTADARSLNRLAVPPEGLNKTSNVSFRIDRDLKTQADILFSQLGLNMTTAFNIFLRQAVRKGCIPFDITINTPNAETITALLEAERIARDPSVQHDDVEKALEELKS

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Crispr_ID: NC_015172_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015172_4

1394571-1394800

Unclear

Consensus_repeat	Method
CTTGTAATTTAACCAGAATGGAATGTAAAG	CRISPRCasFinder

3 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of NC_015172_4

>merge|NC_015172|4|1394571-1394800|CRISPRCasFinder
AAGGTCATTTAGCCATAGTGGAATGTAAACATCCGCCAGCGTCAGATCATCAAAAGAGACATTCCGCCTTGTAATTTAGCCATAGTGGAATGTAAACCAAAGTAAGGCATGGCCTGACAGGCTTCTTCATCTCTTGTAATTTAACCAGAATGGAATGTAAACACGATACCGATTATGGCAGTGAAATTGATACGTTGCGCCTTGTAATTTAGCCAGAGTTGGATGTAAAG

>NC_015172|4|4|1394571-1394800|CRISPRCasFinder
AAGGTCATTTAGCCATAGTGGAATGTAAAC	ATCCGCCAGCGTCAGATCATCAAAAGAGACATTCCGC
CTTGTAATTTAGCCATAGTGGAATGTAAAC	CAAAGTAAGGCATGGCCTGACAGGCTTCTTCATCT
CTTGTAATTTAACCAGAATGGAATGTAAAC	ACGATACCGATTATGGCAGTGAAATTGATACGTTGCGC
CTTGTAATTTAGCCAGAGTTGGATGTAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015172.1\|WP_013624559.1\|1384237_1385950_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09754_cas8b2_CAS-I-B	gnl\|CDD\|187884
NC_015172.1\|WP_041445151.1\|1390112_1390601_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_015172.1\|WP_013624566.1\|1393802_1394090_+\|transposase	unknown	unknown	gnl\|CDD\|225511
NC_015172.1\|WP_013624569.1\|1396704_1398786_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|223650
NC_015172.1\|WP_148228096.1\|1394047_1394551_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_015172.1\|WP_013624571.1\|1399803_1400673_+\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|275263
NC_015172.1\|WP_041445156.1\|1396024_1396699_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_015172.1\|WP_013624565.1\|1391611_1391890_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_015172.1\|WP_013624567.1\|1395005_1396028_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_015172.1\|WP_013624577.1\|1405080_1405935_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NC_015172.1\|WP_013624576.1\|1402770_1404924_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NC_015172.1\|WP_013624558.1\|1383493_1384222_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_015172.1\|WP_013624561.1\|1386805_1387564_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|273860
NC_015172.1\|WP_013624570.1\|1398775_1399555_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_015172.1\|WP_013624575.1\|1402373_1402706_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|274102
NC_015172.1\|WP_013624560.1\|1385946_1386819_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|274215
NC_015172.1\|WP_013624572.1\|1400871_1401414_+\|glutathione-peroxidase	unknown	unknown	gnl\|CDD\|223463
NC_015172.1\|WP_013624573.1\|1401428_1401872_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_015172.1\|WP_013624564.1\|1390612_1391605_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_015172.1\|WP_041445147.1\|1387688_1390058_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707

Protein	Function_ID	Function_description	E-value
NC_015172.1\|WP_013624559.1\|1384237_1385950_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187884	cd09754, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	6.19999e-21
NC_015172.1\|WP_041445151.1\|1390112_1390601_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.36731e-60
NC_015172.1\|WP_013624566.1\|1393802_1394090_+\|transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.603e-10
NC_015172.1\|WP_013624569.1\|1396704_1398786_-\|FtsX-like-permease-family-protein	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	1.44648e-06
NC_015172.1\|WP_148228096.1\|1394047_1394551_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.84918e-31
NC_015172.1\|WP_013624571.1\|1399803_1400673_+\|radical-SAM-protein	gnl\|CDD\|275263	TIGR04470, hypothetical_protein_ALIPUT_00462, radical SAM mobile pair protein B. Members of this family are the downstream member (B) of a pair of tandem-encoded radical SAM enzymes. Most of these radical SAM gene pairs have an additional upstream regulatory gene in the MarR family. Examples of high sequence identity (over 96 percent) from cassettes in several Treponema species of the oral cavity to those in multiple Firmicutes in the gut microbiome suggest recent lateral gene transfer, as might be expected for antibiotic resistance genes. The function is unknown.	6.70797e-21
NC_015172.1\|WP_041445156.1\|1396024_1396699_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.05215e-58
NC_015172.1\|WP_013624565.1\|1391611_1391890_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.48974e-28
NC_015172.1\|WP_013624567.1\|1395005_1396028_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.086e-30
NC_015172.1\|WP_013624577.1\|1405080_1405935_-\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	2.55494e-07
NC_015172.1\|WP_013624576.1\|1402770_1404924_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NC_015172.1\|WP_013624558.1\|1383493_1384222_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	2.14143e-23
NC_015172.1\|WP_013624561.1\|1386805_1387564_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	1.49658e-23
NC_015172.1\|WP_013624570.1\|1398775_1399555_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.06844e-100
NC_015172.1\|WP_013624575.1\|1402373_1402706_-\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	6.55274e-18
NC_015172.1\|WP_013624560.1\|1385946_1386819_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	6.72318e-56
NC_015172.1\|WP_013624572.1\|1400871_1401414_+\|glutathione-peroxidase	gnl\|CDD\|223463	COG0386, BtuE, Glutathione peroxidase [Posttranslational modification, protein turnover, chaperones].	7.90356e-89
NC_015172.1\|WP_013624573.1\|1401428_1401872_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.8115e-22
NC_015172.1\|WP_013624564.1\|1390612_1391605_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	8.00744e-164
NC_015172.1\|WP_041445147.1\|1387688_1390058_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	2.17665e-56

>NC_015172.1|WP_148228096.1|1394047_1394551_+|IS3-family-transposase
MKKGGSLLREKPEIEKYKFIKAESAKYKIAKLCRILHVSRSTYYVWDKPPESKRSIRRKELIEAVKQNFYENKMIPGSLKIAENLSKPEAPVNRKLVAKIMKENGLKSKVVKKYKATTNSNHKLPVAENILNREFTAEKPNQKWVSDITYVPTDEGWLYVAGILDLF
>NC_015172.1|WP_013624566.1|1393802_1394090_+|transposase
MAKNFDQAYKLEICKRVVENRESVTAVAREVGIYENTVYGWVARYRQNSSKPFVGSGHVKAEDEELKRLAKENKELREEIEILKKAAAYFAKNQK
>NC_015172.1|WP_013624565.1|1391611_1391890_+|CRISPR-associated-endonuclease-Cas2
MYIILVYDIEMDEGGARASRRIFKTCKKYLTHVQKSVFEGDITPALLKKLQAELSAYIREDRDSVLVFKSREERWLQKEFWGKEDDKTSNFF
>NC_015172.1|WP_013624564.1|1390612_1391605_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MAESFYLFSNGELQRKDNVLRMVAPDGRFKDIKVEMTRDIYLFGEVSLNTKCLNYAGQLSIPIHIFNYYGFYTGSFYPKEENVSGKLLIGQVQHYTDPRQRLEIARAFIEAASYNMLRNLRYYNERSRDLEACMAEIRGLRKGIETAKDIQELMGVEGSIRKAYYGSWKEIINQEIDFEKRVKRPPDNMINALISFVNSLVYVTCLTEIYKTQLHPAVSYLHSAGERRFSLCLDIAEVFKPLIADRLIFSMLNKKMLTEKDFERESNFCYLKEAGRKRLLEQYDEDLNRTIRHKGLNKNVSYRYLIRLECYKLIKHLMGDKQYEGFMIWW
>NC_015172.1|WP_041445151.1|1390112_1390601_+|CRISPR-associated-protein-Cas4
MHITGTMFYYYFVCRRKLWCFSQHITLENESERVLLGKILDDMAYGREHKHIMIDETVNVDFIKDWKILHEIKKSKSIEEASIWQVKYYLYFLNQRGIKIEKGILDYPKIKEREEIRLEPGDEEKIKRILQDIEEIVSQEKMPPPVNAKICKSCAYYEYCYV
>NC_015172.1|WP_041445147.1|1387688_1390058_+|CRISPR-associated-helicase/endonuclease-Cas3
MDESALAKSQPKEDIQTHTDGLLCNLNILKELYPNLFADWDKLYELLRLACLYHDMGKLYPRFQYCIARRIPYDGIPHGLLSLAFIDWKRLRQEKGLNNDDLKLLYQAVAYHHDRKMPMGNKEIEAEFPKLREGWERFEYSELPWKGEIQKVINQRYFGVGKRIGKRDQDLFPRFIKLEGLLIRLDYAASAHVKVEHPNDFLAQDMEGLIERWRKNGIGTKWNDLQLYMSQNRDKNVIAIAQTGMGKTEAGLLWLGNAKGFFTLPLKSAINAIYQRIIDEIVMEKKDERVGLLHSDTYTQYLQLKEESAKGKETKEEEEDIPADLYYARTRQLSLPLTVCTLDQLFDFVFLYWGFERKLATLAYAKIIIDEVQMYSPELMAYLILGLRYITGMGGRFAILTATLPAFFIDLLREEKIPFAPRRTFTDGRIRHSLKVIAKAISGEDIVELSRQYPGKKILVICNTVKSAVNLYRQLRWDQDLQEVKLVDVNGKEGDPSEDRDGEREASGVNLLHSCFIKRDRREKERLILKMGEKDSNQSGIWIATQIVEASLDIDFDLLFTELSDLNGLFQRMGRCYRKRELKGTPYNCFVFTGGSKPCSGVGVFIDQEIHRLSQAALAETDGILREAQKVEMIEKLYTKENLPEYYEHIKKDLAYADCWSVGEIKASKAKEKFRDIDNVAVIPRQVYETYRQEIAQAQSILQMDYSGMTEEQIRELKESKAKARNAIMDFTVDISRSWYQDIETDQILELNRYERVPIVKGDYNSQVGMIRPALKKNAEFTDFSSRSF
>NC_015172.1|WP_013624561.1|1386805_1387564_+|type-I-B-CRISPR-associated-protein-Cas5
MKAVRVRLHQDMVNYKKPTSFQLKETYPLPPHSTVIGMVHSLCGYTEYQPMQVSVQGKYFSRVNDLYTRYEFKNAMKYEAARHQLQAGEYGINQGVATAELLVDVELLLHIMPEDQEKVEEIHQALKNPKEYPSLGRREDLATFEEVKVVELSLTELEEPVDAPDDYYAYIPLSLLEDESVQLLHHNRVMGDRQPGTRYRLTKDYELVDYGTKKAPKRFRRWNKVDVIYGVPTALIEGKVTLDEDGLVAYLV
>NC_015172.1|WP_013624560.1|1385946_1386819_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKSKGLTLTIIFQAESANYGESVGNVAALKKISRDRGDQYTYISRQALRYNIAEQLGEDLAPVKAEGSGEKKVIQFSEEATIEHYPEIDFFGYLKTEKGTGGKKRSAKVRLSHAISLEPFHGDLDFLTNKGQADKIKENMNIAQAEIHRSYYRYTVTADLDQIGEDEVYDISLPGAERARRVKKLLDTLAFLYRDIRGRREDLKPLFAIGGVYDIKNPVFQNVVDVKNNTVNIAEIEGVLYDNIKEDTYCGVVENSFVNTGALKETLGASSMPAFFTKLKEKVDQYYEGR
>NC_015172.1|WP_013624559.1|1384237_1385950_+|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MEEEILRLRLGDWQWNGAVIGFIRIVGRENVLFENESIKFSSKLLENFEEKYFAYFIKAYEKTLSWYKIVSFKEWLEAQEDDEFGTFVLKDLNALNEQIKTVKSLIKSNSYKAAYELMALGEDILVWEKELVSIKEPKSEQAFAADKPELIAKVRETFSTLRKIISYCESPEGKRYIRAKNIIYTVIKNAWNGVSFLNPQTKEKDVYLDYKAHFVDGAIAYLKQNKDKFKYHCFICDEPIKDMSLDLSFMNATGFDVARKSSHVWDFQNDIAVCPLCKLIYSCLPAGFTYVYDRGIYININTSVEDAYEVNYKIHHEVLRKEGNLRSIYPVLIGALHEQENAGASYELADIQVVRYEREAYRFNILSRKMLQLIFDSKDRLDSLINTSFAENKLTVRIYDEAISRIFNNQNLFTLIHRMLYDLLSDPSKCRFNGAHITHLLRINQRIYQTLGGMKMGCEDKDNALVREARTAGEQLKRYYYGKNAQHKLPGICYRLLNALKTSNQEMFLDVTLNCYLYVGFPVQRVHTDSLGQEKDFSTVGYAFVAALIDNSKSEDKGSSPVGEMEEEKK
>NC_015172.1|WP_013624558.1|1383493_1384222_+|CRISPR-associated-endoribonuclease-Cas6
MRIKVELETKEETLPLNYREKFLSYLKKIFEDHNRDIYQALYSSGANYKPLCSAIYFRPEVEIVKTGITLKSKRFVATFTTRDVMMGVHLINALLSRRNHWAPLADTGNQLKITAVTKVREHEMTDTAAFRILSPVVVRDHDQKEGRDWYLTFEDKLFEAVWKRNLKSELRTVLGRDAGHDVDGLNIKPIQLRKTVVLCYSIYLPCTIGTFALEGEPYLLDYLYKSGLGSKRSLGFGCLDIL
>NC_015172.1|WP_013624567.1|1395005_1396028_-|HAMP-domain-containing-histidine-kinase
MKRRDMSLKAEKQWLNLLLFTDLFFIFLVWLAGPDTFGGLIVIILLFTAVIVLAGYWLDRIRQKNQMEVLQSFLSSPDEETEQRLFAILDASWHPMIRMASARLREQSQALSDKQLELQSYQEFIEAWTHQIKTPLSLATLILANHREEMSSYVYHRMEHVRCTVNSDVERILYYARLQADHADDQFAKMSLSDCVQECLENFRAISGEKNIDVQLNLKPLQVVSDKKVLAFMLSQLFSNAFKYSAPDNGVVRVVSWPDTADDGKIHLAVRDNGKGVPPEDLPFLFDKGFTGSCPERQNATGMGLYLVKKYAEALSVEVKIEPISISGQGFGIELIFPQV
>NC_015172.1|WP_041445156.1|1396024_1396699_-|response-regulator-transcription-factor
MPRIMVIEDDIYLREELVHTFIKKGYSVLSISSFDAPEEEILDSNPDLALLDLNLPGSSGFELCKRLKARASFPILVLTARDTLSDELYALELGADDFLTKPCHSDRLIARAERLLQTYGKVRNLVQAGGLVLDLDTYKVIWQNAHVVLSDTEGKFLRVLLEQYPDVVSKQRLLVELWGGEAYVDENILQVNVTRLRKSLAAIGLREMIQTERGQGYRLEVRKS
>NC_015172.1|WP_013624569.1|1396704_1398786_-|FtsX-like-permease-family-protein
MFFEQIRRNAAKNRKNNGLFFGSLIVAIIAFYTLLSLGDQDVMRFLKTMESDAVHKLMLLIPVIYLISLFFVFFLVYFSYRYQMDNRKKEFGLCLMLGMKRSKLFAMLMSEAVWNSLVSILLGLPLALLLTEGISLTTAKLVGLGIIGHKISFSIPAVLGTIAGFIAVQLIAMLFLSLEFSRKQPLELLRSDCAQKQVSLSGKKGGLCFVFGLIFLILAYVAGIRLLKSFDPQIVALIFILGGSGTFLLYRGLGVFIGHHIRRKSPMRSGLFTFTSRQIQENVLHQYKALAVSSLLLLLALACLSFGIGVASGRGSAETRTADFSIRGSEQEVRAVLDSEASKPMISVYYPMFLSSMETNIYDQTGAVLQSKPNAHEFSWDGLQAALAKLPATDLRNNIMKNFSDRSAPNLISESSYNDLLQAIGKKPLRLEKDQAALYTSIPDSSEFIGVLDSALKSGAYIEVDGRKYELLPGIYQDNVVADRAITLYSGLIVSDENYRNWASDRSEVFCWNVVLSPKVIEEKGLMQAIQLMEQHLAGTGLEYESYISGIGRNLFYTVAASYLTIYLGILFMVIANTVIGLKYLMQQRANQRRYLTLLMFGAGIKDLCKSAKEQIQLFFALALGIAVLNSVFAIWSMFTSFLKLPAETPFAKVVLLAGTAFSLFVVIEFIYISIVEQTSKREIQALRVTDGG
>NC_015172.1|WP_013624570.1|1398775_1399555_-|ABC-transporter-ATP-binding-protein
MNPKRILRVEQITKSYGKGDNVTEALKGISFDVLEGEFLGIMGASGSGKTTLLNCIATMIKPTSGKILLQSSDISSFKGTQLADYRGREIGYLFQEFELLDNLTARENIILPLSLHHVTGRQAEPELQELADRLDIKGVLDKFPAQMSGGQKQRVAAARALISKPSIVLADEPTGALDSKNSKILMDKLSAINKDQQKTILLVTHNALAASYCSRILFIQDGRLFHELRKNIETETPDRFYGRIVTVMAQLGGGSANVL
>NC_015172.1|WP_013624571.1|1399803_1400673_+|radical-SAM-protein
MHDKEVKGILSAKNGMNLYRGCTHGCIYCDSRSRCYQMDHDFEDVEIKRNAPELLEAALRRKRRRCMITTGSMCDPYLPLEKKEKLTRCCLELIDSYGFGFSVITKSHLVLRDLDLLKRINRKTKCVVQMTLTTVDEDLCRVLEPKVCTTAKRAEVLNILRDEGIPTVVWLSPILPFINDTEANLRGILNRCFEAKVKGVICFGMGVTLREGDREYFYKKLDEHFPGMKQRYIETFGNRYSCDSPNQTNLMKIFREQCQRQGVLHSPDAVFTYLNEFEDKQSGEQMTLF
>NC_015172.1|WP_013624572.1|1400871_1401414_+|glutathione-peroxidase
MSVYDYEYTSIENRPVQMSEYQGQVVLIVNTASKCGFTPQYKGLEELYRRYRDQGFTVIGFPCNQFMEQEKGSNEQISEFCSVRYGVTFPLSQKVDVRGETAIPLYQYLTSQKGFEGLGKGIKAKALELTLKARYKDGFADEQIKWNFTKFLIDRNGKVVSRYEPIVEPKDIASDIEKLL
>NC_015172.1|WP_013624573.1|1401428_1401872_+|MarR-family-transcriptional-regulator
MDNQILKLENQLCFPLYAAAKEVVNRYKPFLDEIELTYTQYIAMMVLWEYKSIGVKELGRRLYLDSGTLTPLLKRLEGKGLVRRERSREDERAVKITITEAGEKLQEKASGIPQQMRKCLPLSEEEAGMLYTLLYQLLEGSHREGQA
>NC_015172.1|WP_013624575.1|1402373_1402706_-|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MSCDTADARSLNRLAVPPEGLNKTSNVSFRIDRDLKTQADILFSQLGLNMTTAFNIFLRQAVRKGCIPFDITINTPNAETITALLEAERIARDPSVQHDDVEKALEELKS
>NC_015172.1|WP_013624576.1|1402770_1404924_+|RNA-binding-transcriptional-accessory-protein
MENVVRILAREFNKSEEHVQNVIDLIDQGNTIPFIARYRKEMHGTMDDTVLRNLTDRLNYLRNLAARREEVKKAIEVQEKLTGELAAQIDTAQTLAEVEDIYRPYKQKRRTRATAAREKGLEPLATRLLEQNKDLPDIRELAAEYIDPEKGVESLDAALAGAADIIAETAADSPQIRGRLRELMMNKGYLHAAAEKDEDSVYSLYYTFRQPLSRLQGHQILAINRGEKEGYLKVSAEIDREWALEFVWKALVKPGSSASDFVRCAAEDGYDRLLFPSIKREVRGILTDTAAEGAIHNFALNLKPLFMQPPVKGHVTMGLDPGYRNGCKVAVVDGTGKVLDTAVVYPTYGERQKTEAIEALERLIRKHGVEHIAIGNGTASRETEQMTCELISRTPGVSYMIVNEAGASVYSASKLAAEEFPQYDVNLRSAVSIARRMQDPLAELVKIDPKAIGVGQYQHDMPQKRLDDTLTGVVEDCVNAVGVDVNTASPSLLQRVSGLNGTSAKNIVVYREENGTFISRRQLLKVPKLGPKAYEQCAGFLRIPESKSVLDNTGVHPESYPAAEKLLALCGYKLNDVAGGQISELPERVKGYGEAKAAEECAVGVPTLRDIVKELVKPGRDPRDELPAPLLRTDVIEMKDLTPGMMLTGTVRNVIDFGVFVDIGVHQDGLVHISEMADKFIRHPSEMVAVGDLVKVVVLAVETKKKRISLSMKQAQQ
>NC_015172.1|WP_013624577.1|1405080_1405935_-|ABC-transporter-permease
MSHLLVRNLNVFFRDKTSVFFSLLGVLIIIGLYVLFLGDLVISDLGEIKGARFLIDSWIMAGVLAVSSITAALGAFGTMVDDKAKKVIKDFNASPLSRRSLTAGYIASSFVIGVILTLVALVFAELYIVAYGGRLLDLPAALRLIGVILLSVLSSSSMVCLLVSFLSSMNAFGTASTIIGTLIGFLTGTYIPIGIFPDPIQTVIRLFPVSHSGVLFRQLMMDVPLRESFAGAPSSAANAFREEMGVVFTYGGNVFPWWGSVLVLAATALVFYSLALFRLTRKSR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_015172_1	1.1\|861160\|33\|NC_015172\|CRISPRCasFinder	861160-861192	33	NC_015172.1	861331-861363	1	0.97
NC_015172_1	1.1\|861160\|33\|NC_015172\|CRISPRCasFinder	861160-861192	33	NC_015172.1	862264-862296	1	0.97
NC_015172_3	3.48\|1393649\|36\|NC_015172\|CRISPRCasFinder	1393649-1393684	36	NC_015172.1	756822-756857	2	0.944

1. spacer 1.1|861160|33|NC_015172|CRISPRCasFinder matches to position: 861331-861363, mismatch: 1, identity: 0.97

gccgctgacgctgcccgtgctgtagcagttttc	CRISPR spacer
gccgctgacgctgcccgtgctgtggcagttttc	Protospacer
***********************.*********

2. spacer 1.1|861160|33|NC_015172|CRISPRCasFinder matches to position: 862264-862296, mismatch: 1, identity: 0.97

gccgctgacgctgcccgtgctgtagcagttttc	CRISPR spacer
gccgctgacgctgcctgtgctgtagcagttttc	Protospacer
***************.*****************

3. spacer 3.48|1393649|36|NC_015172|CRISPRCasFinder matches to position: 756822-756857, mismatch: 2, identity: 0.944

ttgatcacgttgtcttcagagatatttacaaactgc	CRISPR spacer
ttgattatgttgtcttcagagatatttacaaactgc	Protospacer
*****.*.****************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015172_2	2.24\|896356\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896356-896388	33	NZ_CP031668	Staphylococcus aureus strain 199 plasmid pPS00120.1A.1, complete sequence	15647-15679	6	0.818
NC_015172_2	2.24\|896356\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896356-896388	33	NZ_CP031671	Staphylococcus aureus strain 64 plasmid pPS00119.1A.1, complete sequence	15648-15680	6	0.818
NC_015172_2	2.22\|896225\|34\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896225-896258	34	LT603679	Enterococcus faecium isolate Ef_DMG1500501 genome assembly, plasmid: 2	154244-154277	7	0.794
NC_015172_2	2.24\|896356\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896356-896388	33	NC_007056	Staphylococcus phage EW, complete genome	15851-15883	7	0.788
NC_015172_2	2.24\|896356\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896356-896388	33	AY954959	Bacteriophage EW, complete genome	15851-15883	7	0.788
NC_015172_2	2.6\|895181\|33\|NC_015172\|CRISPRCasFinder,CRT	895181-895213	33	MK448716	Streptococcus phage Javan249, complete genome	21103-21135	8	0.758
NC_015172_2	2.8\|895311\|33\|NC_015172\|CRISPRCasFinder,CRT	895311-895343	33	NZ_CP053316	Bacillus circulans strain GN03 plasmid unnamed, complete sequence	26986-27018	8	0.758
NC_015172_2	2.19\|896030\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896030-896062	33	NZ_CP017076	Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence	1390372-1390404	8	0.758
NC_015172_2	2.20\|896095\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896095-896127	33	NZ_CP017294	Pseudomonas aeruginosa strain PA83 plasmid unnamed1, complete sequence	223889-223921	8	0.758
NC_015172_2	2.27\|896555\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896555-896587	33	NC_014841	Pantoea sp. At-9b plasmid pPAT9B04, complete sequence	184202-184234	8	0.758
NC_015172_2	2.13\|895638\|32\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	895638-895669	32	CP006880	Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence	1572307-1572338	9	0.719
NC_015172_2	2.20\|896095\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896095-896127	33	NC_042345	Phage Salvo, complete genome	18760-18792	9	0.727
NC_015172_2	2.20\|896095\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896095-896127	33	LR743524	Xylella phage Bacata genome assembly, chromosome: 1	25806-25838	9	0.727
NC_015172_2	2.21\|896160\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	896160-896192	33	KJ564036	Lactobacillus phage Ld25A, complete genome	31052-31084	9	0.727
NC_015172_2	2.42\|897536\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	897536-897568	33	NZ_CP039706	Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence	392790-392822	9	0.727
NC_015172_2	2.42\|897536\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	897536-897568	33	NZ_CP033246	Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence	95111-95143	9	0.727
NC_015172_2	2.42\|897536\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	897536-897568	33	NZ_CP033248	Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence	95152-95184	9	0.727
NC_015172_2	2.42\|897536\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	897536-897568	33	NZ_AP019717	Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence	424924-424956	9	0.727
NC_015172_2	2.42\|897536\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	897536-897568	33	NZ_CP039703	Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence	283979-284011	9	0.727
NC_015172_2	2.42\|897536\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	897536-897568	33	NZ_CP013238	Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence	402334-402366	9	0.727
NC_015172_2	2.13\|895638\|32\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	895638-895669	32	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	529783-529814	11	0.656
NC_015172_2	2.42\|897536\|33\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	897536-897568	33	KJ025957	Serratia phage PS2, complete genome	14770-14802	11	0.667
NC_015172_2	2.43\|897601\|34\|NC_015172\|CRISPRCasFinder,CRT,PILER-CR	897601-897634	34	NZ_CP025124	Planococcus sp. MB-3u-03 plasmid unnamed1, complete sequence	13193-13226	11	0.676
NC_015172_4	4.2\|1394668\|35\|NC_015172\|CRISPRCasFinder	1394668-1394702	35	NZ_CP035515	Haematobacter massiliensis strain OT1 plasmid pOT1-5, complete sequence	10621-10655	11	0.686

1. spacer 2.24|896356|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031668 (Staphylococcus aureus strain 199 plasmid pPS00120.1A.1, complete sequence) position: , mismatch: 6, identity: 0.818

aacattaaaatccgaatacccaatatttatagc	CRISPR spacer
caccataaaatccgaatacccaaagtttataac	Protospacer
 **  ****************** .******.*

2. spacer 2.24|896356|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031671 (Staphylococcus aureus strain 64 plasmid pPS00119.1A.1, complete sequence) position: , mismatch: 6, identity: 0.818

aacattaaaatccgaatacccaatatttatagc	CRISPR spacer
caccataaaatccgaatacccaaagtttataac	Protospacer
 **  ****************** .******.*

3. spacer 2.22|896225|34|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to LT603679 (Enterococcus faecium isolate Ef_DMG1500501 genome assembly, plasmid: 2) position: , mismatch: 7, identity: 0.794

--tcagatatgtttatctaattagattttagtactt	CRISPR spacer
aattag--ctttttatctaatcagattttagtacta	Protospacer
  *.**   * **********.*************

4. spacer 2.24|896356|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NC_007056 (Staphylococcus phage EW, complete genome) position: , mismatch: 7, identity: 0.788

aacattaaaatccgaatacccaat-atttatagc	CRISPR spacer
aactttaaaatcagaatacccaatcggttctaa-	Protospacer
*** ******** *********** . ** **.

5. spacer 2.24|896356|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to AY954959 (Bacteriophage EW, complete genome) position: , mismatch: 7, identity: 0.788

aacattaaaatccgaatacccaat-atttatagc	CRISPR spacer
aactttaaaatcagaatacccaatcggttctaa-	Protospacer
*** ******** *********** . ** **.

6. spacer 2.6|895181|33|NC_015172|CRISPRCasFinder,CRT matches to MK448716 (Streptococcus phage Javan249, complete genome) position: , mismatch: 8, identity: 0.758

agctaattcggcttgtgataagtcatttccgat	CRISPR spacer
cgctaattcggactgtgataagtcataagcgtc	Protospacer
 ********** .*************   ** .

7. spacer 2.8|895311|33|NC_015172|CRISPRCasFinder,CRT matches to NZ_CP053316 (Bacillus circulans strain GN03 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.758

atacatttcgatctggaacgataaaatcacggc	CRISPR spacer
atcaatttctatctggaacgaaaaaatcataat	Protospacer
**  ***** *********** *******....

8. spacer 2.19|896030|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017076 (Novosphingobium resinovorum strain SA1 plasmid pSA1, complete sequence) position: , mismatch: 8, identity: 0.758

agcttgcgtcttcgcttccgccattctgggccg	CRISPR spacer
gggtatcctcttcgctaccgccgttctgggcct	Protospacer
.* *  * ******** *****.*********

9. spacer 2.20|896095|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017294 (Pseudomonas aeruginosa strain PA83 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.758

ttcctggcgctggctttcgcgcccttcacaaaa	CRISPR spacer
ctcctggcgctggctatagcgccctaccggaat	Protospacer
.************** * ******* *  .**

10. spacer 2.27|896555|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NC_014841 (Pantoea sp. At-9b plasmid pPAT9B04, complete sequence) position: , mismatch: 8, identity: 0.758

ttgagattattgttttgttatgattatgatttg	CRISPR spacer
tcctgattattgttttgtgatgattatcataaa	Protospacer
*.  ************** ******** **  .

11. spacer 2.13|895638|32|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to CP006880 (Rhizobium gallicum bv. gallicum R602 plasmid pRgalR602c, complete sequence) position: , mismatch: 9, identity: 0.719

tgggttccaggatcacgccggtctgtttgttc	CRISPR spacer
aggcgaccaggatcacgccggcctgcttggcg	Protospacer
 **   ***************.***.*** .

12. spacer 2.20|896095|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NC_042345 (Phage Salvo, complete genome) position: , mismatch: 9, identity: 0.727

ttcctggcgctggctttcgcgcccttcacaaaa	CRISPR spacer
atgctggcgctggcgttcgcgaccttctggtac	Protospacer
 * *********** ****** *****  . *

13. spacer 2.20|896095|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to LR743524 (Xylella phage Bacata genome assembly, chromosome: 1) position: , mismatch: 9, identity: 0.727

ttcctggcgctggctttcgcgcccttcacaaaa	CRISPR spacer
atgctggcgctggcgttcgcgaccttctggtac	Protospacer
 * *********** ****** *****  . *

14. spacer 2.21|896160|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to KJ564036 (Lactobacillus phage Ld25A, complete genome) position: , mismatch: 9, identity: 0.727

atcgtgtttcccccttttgacagaaaaaaggtc	CRISPR spacer
cacatttttcccctttttgaaagaaaaaagtgg	Protospacer
  *.* *******.****** *********

15. spacer 2.42|897536|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039706 (Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence) position: , mismatch: 9, identity: 0.727

aaagaacaaagtttaaggaattatgcacttttt	CRISPR spacer
aaataacaaagtttaaggaatcatatttattag	Protospacer
*** *****************.**.. . **

16. spacer 2.42|897536|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033246 (Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence) position: , mismatch: 9, identity: 0.727

aaagaacaaagtttaaggaattatgcacttttt	CRISPR spacer
aaataacaaagtttaaggaatcatatttattag	Protospacer
*** *****************.**.. . **

17. spacer 2.42|897536|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033248 (Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence) position: , mismatch: 9, identity: 0.727

aaagaacaaagtttaaggaattatgcacttttt	CRISPR spacer
aaataacaaagtttaaggaatcatatttattag	Protospacer
*** *****************.**.. . **

18. spacer 2.42|897536|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP019717 (Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence) position: , mismatch: 9, identity: 0.727

aaagaacaaagtttaaggaattatgcacttttt	CRISPR spacer
aaataacaaagtttaaggaatcatatttattag	Protospacer
*** *****************.**.. . **

19. spacer 2.42|897536|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039703 (Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence) position: , mismatch: 9, identity: 0.727

aaagaacaaagtttaaggaattatgcacttttt	CRISPR spacer
aaataacaaagtttaaggaatcatatttattag	Protospacer
*** *****************.**.. . **

20. spacer 2.42|897536|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013238 (Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence) position: , mismatch: 9, identity: 0.727

aaagaacaaagtttaaggaattatgcacttttt	CRISPR spacer
aaataacaaagtttaaggaatcatatttattag	Protospacer
*** *****************.**.. . **

21. spacer 2.13|895638|32|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 11, identity: 0.656

tgggttccaggatcacgccggtctgtttgttc	CRISPR spacer
gcggttccgggatcacgccggcctgcgccagt	Protospacer
  ******.************.***. .   .

22. spacer 2.42|897536|33|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to KJ025957 (Serratia phage PS2, complete genome) position: , mismatch: 11, identity: 0.667

aaagaacaaagtttaaggaattatgcacttttt	CRISPR spacer
caacaacaaattttaaggaattatgatggccca	Protospacer
 ** ****** **************    ...

23. spacer 2.43|897601|34|NC_015172|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP025124 (Planococcus sp. MB-3u-03 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.676

gaaaaagcgggattgattgtatactgcaaagatg	CRISPR spacer
atgctggcgggcttgattgtctactgcaaaaccg	Protospacer
. .  .***** ******** *********. .*

24. spacer 4.2|1394668|35|NC_015172|CRISPRCasFinder matches to NZ_CP035515 (Haematobacter massiliensis strain OT1 plasmid pOT1-5, complete sequence) position: , mismatch: 11, identity: 0.686

caaagtaaggcatggcctgacaggcttcttcatct	CRISPR spacer
ggccatggtgcttggcctgacaggcatcttcatcg	Protospacer
 .  .*.. ** ************* ********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

48210 : 97979

Bacillus_phage(22.22%)

transposase,integrase

attL 64010:64026|attR 93852:93868

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013623294.1\|48210_49824_+\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	4.3e-11	22.3
WP_013623295.1\|49820_50789_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013623296.1\|50781_51807_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013623298.1\|52125_52509_-	DUF4406 domain-containing protein	A0A2K5B270	Erysipelothrix_phage	1.1e-16	38.9
WP_013623299.1\|52528_53434_-	hypothetical protein	NA	NA	NA	NA
WP_167875176.1\|53631_53799_+	hypothetical protein	NA	NA	NA	NA
WP_013623301.1\|53890_54229_-	DUF3852 domain-containing protein	NA	NA	NA	NA
WP_013623302.1\|54782_56483_-	hypothetical protein	NA	NA	NA	NA
WP_013623303.1\|56549_57122_-	hypothetical protein	NA	NA	NA	NA
WP_013623304.1\|57230_57779_-	hypothetical protein	NA	NA	NA	NA
WP_013623305.1\|57775_58171_-	DUF4320 family protein	NA	NA	NA	NA
WP_013623306.1\|58164_58821_-	hypothetical protein	NA	NA	NA	NA
WP_013623307.1\|58833_59706_-	hypothetical protein	NA	NA	NA	NA
WP_013623308.1\|59716_60646_-	membrane protein	NA	NA	NA	NA
WP_013623309.1\|60642_62175_-	type II/IV secretion system ATPase subunit	NA	NA	NA	NA
WP_013623310.1\|62168_62984_-	ATPase AAA	NA	NA	NA	NA
WP_013623311.1\|62983_63808_-	Flp pilus assembly protein CpaB	NA	NA	NA	NA
WP_013623313.1\|63967_64420_-	prepilin peptidase	NA	NA	NA	NA
64010:64026	attL	NA	NA	NA	NA
WP_013623314.1\|64409_64640_-	hypothetical protein	NA	NA	NA	NA
WP_013623315.1\|64808_66608_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	4.9e-32	32.0
WP_013623316.1\|67154_71093_-	S-layer homology domain-containing protein	NA	NA	NA	NA
WP_013623317.1\|71103_71463_-	septation protein SpoVG family protein	NA	NA	NA	NA
WP_013623318.1\|71496_71760_-	hypothetical protein	NA	NA	NA	NA
WP_013623319.1\|71816_72371_-	hypothetical protein	NA	NA	NA	NA
WP_013623320.1\|72412_72985_-	hypothetical protein	NA	NA	NA	NA
WP_013623321.1\|73048_73879_-	DNA adenine methylase	A0A2H4IYF4	uncultured_Caudovirales_phage	3.4e-52	43.9
WP_013623322.1\|73887_74220_-	hypothetical protein	NA	NA	NA	NA
WP_013623323.1\|74359_74647_-	hypothetical protein	NA	NA	NA	NA
WP_148228160.1\|74725_75958_-	hypothetical protein	NA	NA	NA	NA
WP_013623325.1\|76208_76937_-	DUF4314 domain-containing protein	A0A127AWR5	Bacillus_phage	1.4e-09	47.3
WP_027096094.1\|77256_77853_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_148228039.1\|78251_79550_-\|integrase	tyrosine-type recombinase/integrase	A0A2R2ZGM9	Clostridioides_phage	3.6e-24	27.8
WP_013623329.1\|79626_79842_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013623330.1\|80110_81034_+	Fic family protein	NA	NA	NA	NA
WP_013623331.1\|81192_83370_+	AAA family ATPase	NA	NA	NA	NA
WP_041444523.1\|83362_85144_+	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	3.6e-19	25.0
WP_013623333.1\|85208_85958_+	DUF2971 domain-containing protein	NA	NA	NA	NA
WP_013623334.1\|86050_90577_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_148228040.1\|90826_91561_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	6.7e-44	41.3
WP_013623336.1\|91557_93066_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_013623337.1\|93200_93422_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013623338.1\|94024_95251_+	ATP-binding protein	NA	NA	NA	NA
93852:93868	attR	NA	NA	NA	NA
WP_148228041.1\|95727_95946_+	hypothetical protein	NA	NA	NA	NA
WP_013623340.1\|96826_97979_-\|transposase	IS3 family transposase	Q6H9S6	Enterobacteria_phage	2.7e-15	27.0

DBSCAN-SWA_2

333051 : 356391

Paenibacillus_phage(26.32%)

terminase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013623541.1\|333051_334482_+\|tRNA	cysteine--tRNA ligase	A0A161HRB7	Powai_lake_megavirus	2.1e-41	26.4
WP_013623542.1\|334466_334895_+	ribonuclease III	NA	NA	NA	NA
WP_013623543.1\|334948_335458_+	dihydrofolate reductase	M4M9C1	Vibrio_phage	7.0e-16	33.1
WP_013623544.1\|335450_336224_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_041444539.1\|336319_336979_+	RNA polymerase sporulation sigma factor SigH	NA	NA	NA	NA
WP_013623546.1\|337352_338945_-	recombinase family protein	A0A0A7RTP8	Clostridium_phage	4.7e-50	27.6
WP_013623547.1\|338957_340037_-	type I restriction enzyme HsdR N-terminal domain-containing protein	A0A1S5SAB0	Streptococcus_phage	2.0e-81	46.0
WP_013623548.1\|340063_340669_-	helix-turn-helix domain-containing protein	E5DV74	Deep-sea_thermophilic_phage	2.1e-51	52.3
WP_013623549.1\|340842_341061_+	hypothetical protein	NA	NA	NA	NA
WP_013623550.1\|341095_341266_+	hypothetical protein	NA	NA	NA	NA
WP_013623551.1\|341253_341511_+	hypothetical protein	NA	NA	NA	NA
WP_013623552.1\|341793_342567_+	class I SAM-dependent methyltransferase	A0A2I7RNS1	Vibrio_phage	1.2e-24	40.9
WP_013623553.1\|342598_343576_+	hypothetical protein	A0A2I7RHT9	Vibrio_phage	7.8e-24	47.6
WP_013623554.1\|343559_344120_+	cell wall hydrolase	A0A0K2FM09	Brevibacillus_phage	3.6e-21	43.2
WP_041444542.1\|344123_344570_+	hypothetical protein	H7BVI4	unidentified_phage	2.2e-42	58.5
WP_013623555.1\|344571_345135_+	SAM-dependent DNA methyltransferase	A0A1W6DX30	Sphingobium_phage	1.5e-19	34.5
WP_013623556.1\|345151_345427_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	A0A2I7SC16	Paenibacillus_phage	3.4e-17	56.0
WP_013623557.1\|345423_346716_+	AAA family ATPase	Q5YA97	Bacillus_phage	2.5e-155	66.2
WP_013623558.1\|346715_347801_+	ATP-binding protein	A0A0K2CZH1	Paenibacillus_phage	5.3e-106	52.0
WP_013623559.1\|347826_348276_+	hypothetical protein	A0A2I7SC41	Paenibacillus_phage	1.2e-35	48.4
WP_013623560.1\|348278_349892_+	DEAD/DEAH box helicase family protein	A0A0K2CZF8	Paenibacillus_phage	5.6e-237	76.0
WP_148228162.1\|349884_350508_+	hypothetical protein	A0A0C5K996	Enterococcus_phage	1.4e-39	41.2
WP_013623562.1\|350500_352747_+	AAA family ATPase	A0A2I7SC35	Paenibacillus_phage	0.0e+00	67.5
WP_013623564.1\|353086_353248_+	hypothetical protein	NA	NA	NA	NA
WP_013623565.1\|353237_353630_+	RusA family crossover junction endodeoxyribonuclease	Q5YA86	Bacillus_phage	2.8e-41	60.0
WP_052298589.1\|353683_354001_+	hypothetical protein	NA	NA	NA	NA
WP_013623567.1\|354024_354318_+	hypothetical protein	NA	NA	NA	NA
WP_013623568.1\|354317_354764_+	hypothetical protein	NA	NA	NA	NA
WP_013623569.1\|354858_355386_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_013623571.1\|355668_356391_+\|terminase	terminase small subunit	A0A248SKT2	Klebsiella_phage	2.0e-53	48.3

DBSCAN-SWA_3

519559 : 553760

Faecalibacterium_phage(48.72%)

tail,protease,terminase,capsid,plate,transposase,head,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013623753.1\|519559_520390_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_013623754.1\|521022_521457_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013623755.1\|521611_521854_+	hypothetical protein	A0A2H4JCN6	uncultured_Caudovirales_phage	6.2e-07	56.2
WP_148228055.1\|522051_522234_-	hypothetical protein	NA	NA	NA	NA
WP_013623757.1\|522364_522583_+	helix-turn-helix transcriptional regulator	A0A2H4JHB2	uncultured_Caudovirales_phage	7.3e-15	58.2
WP_013623758.1\|522596_522908_+	hypothetical protein	NA	NA	NA	NA
WP_013623759.1\|523066_525151_+\|transposase	Mu transposase C-terminal domain-containing protein	A0A2H4JGQ6	uncultured_Caudovirales_phage	2.0e-271	66.4
WP_041444955.1\|525168_526143_+	AAA family ATPase	A0A2H4JAW1	uncultured_Caudovirales_phage	5.4e-134	75.3
WP_013623761.1\|526163_526472_+	hypothetical protein	NA	NA	NA	NA
WP_013623762.1\|526471_526984_+	host-nuclease inhibitor Gam family protein	A0A2H4JE65	uncultured_Caudovirales_phage	1.1e-58	65.1
WP_013623763.1\|526995_527466_+	regulatory protein GemA	A0A2H4JAV8	uncultured_Caudovirales_phage	1.3e-53	73.4
WP_013623764.1\|527440_527827_+	hypothetical protein	A0A2K9VGW4	Faecalibacterium_phage	5.1e-27	55.1
WP_013623765.1\|527839_529330_+	N-acetylmuramoyl-L-alanine amidase	A0A2H4JCM7	uncultured_Caudovirales_phage	1.5e-114	47.4
WP_013623766.1\|529348_529678_+	hypothetical protein	A0A2H4JHA5	uncultured_Caudovirales_phage	2.1e-34	64.0
WP_013623767.1\|529798_530233_+	hypothetical protein	A0A2H4JFB1	uncultured_Caudovirales_phage	2.6e-35	62.4
WP_013623768.1\|530245_530542_+	hypothetical protein	A0A2H4JGQ3	uncultured_Caudovirales_phage	2.9e-14	40.6
WP_013623769.1\|530546_530861_+	hypothetical protein	A0A2H4JAV1	uncultured_Caudovirales_phage	1.9e-40	77.9
WP_013623770.1\|530860_531421_+	DUF3486 family protein	H7BVL1	unidentified_phage	3.4e-64	69.9
WP_013623771.1\|531413_533174_+\|terminase	phage terminase large subunit	A0A2H4JE58	uncultured_Caudovirales_phage	1.1e-275	79.3
WP_013623772.1\|533188_534802_+	DUF935 domain-containing protein	A0A2H4JAU9	uncultured_Caudovirales_phage	6.5e-225	71.5
WP_013623773.1\|534794_535538_+\|capsid	minor capsid protein	A0A2K9VGX3	Faecalibacterium_phage	8.7e-100	70.7
WP_013623774.1\|535675_536731_+\|protease	phage protease	A0A2H4JAW3	uncultured_Caudovirales_phage	1.7e-125	64.7
WP_013623775.1\|536732_537143_+	hypothetical protein	A0A2H4JCL7	uncultured_Caudovirales_phage	2.3e-38	62.5
WP_013623776.1\|537170_538058_+\|head	Mu-like prophage major head subunit gpT family protein	H7BVL8	unidentified_phage	6.3e-121	69.2
WP_148228056.1\|538105_538522_+	DUF1320 family protein	A0A2K9VH41	Faecalibacterium_phage	4.2e-43	64.3
WP_013623778.1\|538522_539023_+	phage virion morphogenesis protein	A0A2K9VH22	Faecalibacterium_phage	3.1e-53	63.9
WP_013623779.1\|539025_539538_+	hypothetical protein	A0A2K9VH02	Faecalibacterium_phage	1.5e-50	59.9
WP_013623780.1\|539527_539746_+	hypothetical protein	NA	NA	NA	NA
WP_013623781.1\|539746_541177_+	DUF2586 family protein	A0A2K9VH53	Faecalibacterium_phage	5.9e-145	56.8
WP_013623782.1\|541196_541634_+	hypothetical protein	A0A2K9VGX6	Faecalibacterium_phage	8.8e-52	69.3
WP_013623783.1\|541668_542049_+	hypothetical protein	A0A2K9VGY3	Faecalibacterium_phage	1.3e-22	53.8
WP_013623784.1\|542066_542255_+	hypothetical protein	A0A2K9VH64	Faecalibacterium_phage	1.1e-06	50.8
WP_013623785.1\|542271_542511_-	hypothetical protein	NA	NA	NA	NA
WP_013623786.1\|542562_545001_+\|tail	phage tail tape measure protein	A0A2K9VGW0	Faecalibacterium_phage	8.7e-181	50.4
WP_013623787.1\|545003_545597_+	hypothetical protein	A0A2K9VH28	Faecalibacterium_phage	4.0e-39	50.3
WP_013623788.1\|545613_546369_+	serine/arginine repetitive matrix protein 2	H7BVM5	unidentified_phage	2.0e-99	68.1
WP_013623789.1\|546386_546671_+	hypothetical protein	NA	NA	NA	NA
WP_013623790.1\|546670_547084_+	hypothetical protein	A0A2K9VH11	Faecalibacterium_phage	1.1e-32	50.0
WP_013623791.1\|547076_548207_+\|plate	baseplate J/gp47 family protein	H7BVM7	unidentified_phage	2.0e-124	62.2
WP_013623793.1\|549053_549377_+	hypothetical protein	A0A2K9VGY5	Faecalibacterium_phage	7.2e-27	56.7
WP_148228165.1\|549363_549675_+	inorganic polyphosphate kinase	A0A2K9VGY9	Faecalibacterium_phage	5.3e-27	57.3
WP_041444566.1\|549667_549937_+	hypothetical protein	A0A2K9VH74	Faecalibacterium_phage	2.4e-15	47.4
WP_041444567.1\|549905_550253_+	diversity-generating retroelement protein Avd	A0A2K9VGX0	Faecalibacterium_phage	8.3e-29	61.8
WP_041444965.1\|550521_551640_+	group II intron reverse transcriptase domain-containing protein	H7BVN0	unidentified_phage	8.2e-110	54.0
WP_013623798.1\|551716_553435_+	hypothetical protein	A0A2K9VH60	Faecalibacterium_phage	1.6e-218	66.3
WP_013623799.1\|553434_553623_+	hypothetical protein	A0A2K9VH42	Faecalibacterium_phage	1.1e-06	48.4
WP_013623800.1\|553622_553760_+	hypothetical protein	A0A2K9VH20	Faecalibacterium_phage	4.6e-07	67.5

DBSCAN-SWA_4

1677340 : 1685179

Tupanvirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013624809.1\|1677340_1678333_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	4.2e-49	36.1
WP_013624810.1\|1678604_1679288_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.1e-37	35.9
WP_148228107.1\|1679365_1680793_+	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	2.9e-19	32.0
WP_013624812.1\|1681023_1681974_+	glycosyltransferase family 2 protein	U5P087	Shigella_phage	7.3e-59	40.3
WP_013624813.1\|1681979_1682381_+	GtrA family protein	NA	NA	NA	NA
WP_013624814.1\|1682411_1683086_+	response regulator transcription factor	NA	NA	NA	NA
WP_041445245.1\|1683190_1684093_+	chemotaxis protein CheV	Q56AR1	Bacillus_thuringiensis_phage	3.3e-37	31.4
WP_013624816.1\|1684150_1685179_+	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	7.9e-43	34.9

DBSCAN-SWA_5

2392749 : 2400630

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013625506.1\|2392749_2394291_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.8e-78	51.6
WP_041445377.1\|2394408_2395017_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.0e-26	38.1
WP_013625508.1\|2395022_2396039_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	1.5e-70	45.7
WP_013625509.1\|2396070_2397471_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.8e-61	36.3
WP_083811270.1\|2397496_2399665_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	5.9e-157	44.2
WP_013625511.1\|2399678_2400386_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_013625512.1\|2400387_2400630_-	phosphoribosylformylglycinamidine synthase subunit PurS	E3SNE3	Prochlorococcus_phage	2.6e-05	38.8

DBSCAN-SWA_6

2631734 : 2668594

Faecalibacterium_phage(47.5%)

tail,protease,terminase,capsid,plate,head,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013625735.1\|2631734_2634992_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	8.4e-123	30.2
WP_013625736.1\|2634988_2636203_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_013623800.1\|2636445_2636583_-	hypothetical protein	A0A2K9VH20	Faecalibacterium_phage	4.6e-07	67.5
WP_013623799.1\|2636582_2636771_-	hypothetical protein	A0A2K9VH42	Faecalibacterium_phage	1.1e-06	48.4
WP_013623798.1\|2636770_2638489_-	hypothetical protein	A0A2K9VH60	Faecalibacterium_phage	1.6e-218	66.3
WP_041444965.1\|2638565_2639684_-	group II intron reverse transcriptase domain-containing protein	H7BVN0	unidentified_phage	8.2e-110	54.0
WP_041444567.1\|2639952_2640300_-	diversity-generating retroelement protein Avd	A0A2K9VGX0	Faecalibacterium_phage	8.3e-29	61.8
WP_041444566.1\|2640268_2640538_-	hypothetical protein	A0A2K9VH74	Faecalibacterium_phage	2.4e-15	47.4
WP_148228165.1\|2640530_2640842_-	inorganic polyphosphate kinase	A0A2K9VGY9	Faecalibacterium_phage	5.3e-27	57.3
WP_013623793.1\|2640828_2641152_-	hypothetical protein	A0A2K9VGY5	Faecalibacterium_phage	7.2e-27	56.7
WP_013623791.1\|2641998_2643129_-\|plate	baseplate J/gp47 family protein	H7BVM7	unidentified_phage	2.0e-124	62.2
WP_013623790.1\|2643121_2643535_-	hypothetical protein	A0A2K9VH11	Faecalibacterium_phage	1.1e-32	50.0
WP_013623789.1\|2643534_2643819_-	hypothetical protein	NA	NA	NA	NA
WP_013623788.1\|2643836_2644592_-	serine/arginine repetitive matrix protein 2	H7BVM5	unidentified_phage	2.0e-99	68.1
WP_013623787.1\|2644608_2645202_-	hypothetical protein	A0A2K9VH28	Faecalibacterium_phage	4.0e-39	50.3
WP_013623786.1\|2645204_2647643_-\|tail	phage tail tape measure protein	A0A2K9VGW0	Faecalibacterium_phage	8.7e-181	50.4
WP_013623785.1\|2647694_2647934_+	hypothetical protein	NA	NA	NA	NA
WP_013623784.1\|2647950_2648139_-	hypothetical protein	A0A2K9VH64	Faecalibacterium_phage	1.1e-06	50.8
WP_013623783.1\|2648156_2648537_-	hypothetical protein	A0A2K9VGY3	Faecalibacterium_phage	1.3e-22	53.8
WP_013623782.1\|2648571_2649009_-	hypothetical protein	A0A2K9VGX6	Faecalibacterium_phage	8.8e-52	69.3
WP_013623781.1\|2649028_2650459_-	DUF2586 family protein	A0A2K9VH53	Faecalibacterium_phage	5.9e-145	56.8
WP_013623780.1\|2650459_2650678_-	hypothetical protein	NA	NA	NA	NA
WP_013625737.1\|2650667_2651180_-	hypothetical protein	A0A2K9VH02	Faecalibacterium_phage	1.1e-50	59.9
WP_013623778.1\|2651182_2651683_-	phage virion morphogenesis protein	A0A2K9VH22	Faecalibacterium_phage	3.1e-53	63.9
WP_148228056.1\|2651683_2652100_-	DUF1320 family protein	A0A2K9VH41	Faecalibacterium_phage	4.2e-43	64.3
WP_013623776.1\|2652147_2653035_-\|head	Mu-like prophage major head subunit gpT family protein	H7BVL8	unidentified_phage	6.3e-121	69.2
WP_013623775.1\|2653062_2653473_-	hypothetical protein	A0A2H4JCL7	uncultured_Caudovirales_phage	2.3e-38	62.5
WP_013623774.1\|2653474_2654530_-\|protease	phage protease	A0A2H4JAW3	uncultured_Caudovirales_phage	1.7e-125	64.7
WP_013623773.1\|2654667_2655411_-\|capsid	minor capsid protein	A0A2K9VGX3	Faecalibacterium_phage	8.7e-100	70.7
WP_013623772.1\|2655403_2657017_-	DUF935 domain-containing protein	A0A2H4JAU9	uncultured_Caudovirales_phage	6.5e-225	71.5
WP_013623771.1\|2657031_2658792_-\|terminase	phage terminase large subunit	A0A2H4JE58	uncultured_Caudovirales_phage	1.1e-275	79.3
WP_013623770.1\|2658784_2659345_-	DUF3486 family protein	H7BVL1	unidentified_phage	3.4e-64	69.9
WP_013623769.1\|2659344_2659659_-	hypothetical protein	A0A2H4JAV1	uncultured_Caudovirales_phage	1.9e-40	77.9
WP_013623768.1\|2659663_2659960_-	hypothetical protein	A0A2H4JGQ3	uncultured_Caudovirales_phage	2.9e-14	40.6
WP_013623767.1\|2659972_2660407_-	hypothetical protein	A0A2H4JFB1	uncultured_Caudovirales_phage	2.6e-35	62.4
WP_013623766.1\|2660527_2660857_-	hypothetical protein	A0A2H4JHA5	uncultured_Caudovirales_phage	2.1e-34	64.0
WP_013623765.1\|2660875_2662366_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4JCM7	uncultured_Caudovirales_phage	1.5e-114	47.4
WP_013623764.1\|2662378_2662765_-	hypothetical protein	A0A2K9VGW4	Faecalibacterium_phage	5.1e-27	55.1
WP_013623763.1\|2662739_2663210_-	regulatory protein GemA	A0A2H4JAV8	uncultured_Caudovirales_phage	1.3e-53	73.4
WP_013623762.1\|2663221_2663734_-	host-nuclease inhibitor Gam family protein	A0A2H4JE65	uncultured_Caudovirales_phage	1.1e-58	65.1
WP_013623761.1\|2663733_2664042_-	hypothetical protein	NA	NA	NA	NA
WP_041444955.1\|2664062_2665037_-	AAA family ATPase	A0A2H4JAW1	uncultured_Caudovirales_phage	5.4e-134	75.3
WP_013623759.1\|2665054_2667139_-\|transposase	Mu transposase C-terminal domain-containing protein	A0A2H4JGQ6	uncultured_Caudovirales_phage	2.0e-271	66.4
WP_013623758.1\|2667297_2667609_-	hypothetical protein	NA	NA	NA	NA
WP_013623757.1\|2667622_2667841_-	helix-turn-helix transcriptional regulator	A0A2H4JHB2	uncultured_Caudovirales_phage	7.3e-15	58.2
WP_148228055.1\|2667971_2668154_+	hypothetical protein	NA	NA	NA	NA
WP_013623755.1\|2668351_2668594_-	hypothetical protein	A0A2H4JCN6	uncultured_Caudovirales_phage	6.2e-07	56.2

DBSCAN-SWA_7

2683414 : 2693385

Clostridium_phage(25.0%)

integrase

attL 2678791:2678805|attR 2692789:2692803

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2678791:2678805	attL	NA	NA	NA	NA
WP_013625756.1\|2683414_2683840_-	type II toxin-antitoxin system HicB family antitoxin	A0A0K2CYJ8	Paenibacillus_phage	1.2e-24	45.9
WP_013625758.1\|2684240_2685137_+\|integrase	site-specific integrase	Q8SBN2	Clostridium_phage	3.3e-45	43.9
WP_013625759.1\|2685359_2685677_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013625760.1\|2685678_2686038_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_013625761.1\|2686104_2686308_-	helix-turn-helix transcriptional regulator	A0A2K5B263	Erysipelothrix_phage	2.3e-10	49.2
WP_013625762.1\|2686713_2687091_+	hypothetical protein	NA	NA	NA	NA
WP_013625763.1\|2687087_2687681_+	hypothetical protein	NA	NA	NA	NA
WP_052298647.1\|2687667_2687919_+	Arm DNA-binding domain-containing protein	H7BW99	unidentified_phage	4.9e-15	46.3
WP_052298648.1\|2688003_2688441_+	hypothetical protein	A0A0A8WF08	Clostridium_phage	2.8e-29	49.2
WP_013625764.1\|2688540_2690073_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	4.1e-19	28.9
WP_013625765.1\|2690143_2690689_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	7.7e-13	27.9
WP_013625766.1\|2690842_2691511_-	hypothetical protein	NA	NA	NA	NA
WP_013625767.1\|2691771_2693385_+	ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	1.6e-53	28.2
2692789:2692803	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2958672 : 3023121

Faecalibacterium_phage(41.3%)

tail,protease,terminase,capsid,plate,head,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041445471.1\|2958672_2959302_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_013626009.1\|2959307_2959703_-	(deoxy)nucleoside triphosphate pyrophosphohydrolase	G8DF69	Emiliania_huxleyi_virus	2.3e-06	33.7
WP_013626010.1\|2959780_2961019_-	OB-fold nucleic acid binding domain-containing protein	NA	NA	NA	NA
WP_013626011.1\|2961137_2963495_-	diguanylate cyclase	G3MA91	Bacillus_virus	1.6e-17	35.0
WP_013626012.1\|2963633_2964374_-	response regulator transcription factor	W8CYM9	Bacillus_phage	5.0e-39	38.3
WP_013626013.1\|2964360_2965842_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	7.4e-26	30.2
WP_013626014.1\|2965851_2966604_-	ABC transporter permease	NA	NA	NA	NA
WP_041445475.1\|2966575_2967316_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.1e-33	37.6
WP_013626016.1\|2967437_2968679_-	hypothetical protein	NA	NA	NA	NA
WP_013626017.1\|2968772_2969966_-	MFS transporter	NA	NA	NA	NA
WP_013626018.1\|2969987_2970701_-	glutamine amidotransferase	NA	NA	NA	NA
WP_013626019.1\|2970742_2974564_-	UvrD-helicase domain-containing protein	G3MA40	Bacillus_virus	3.5e-11	22.2
WP_013626020.1\|2974556_2978000_-	helicase-exonuclease AddAB subunit AddB	NA	NA	NA	NA
WP_013626021.1\|2978057_2978399_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013626022.1\|2978596_2979178_+	flavodoxin family protein	NA	NA	NA	NA
WP_013626023.1\|2979270_2980167_+	phosphatidylserine decarboxylase	NA	NA	NA	NA
WP_041444844.1\|2980182_2982321_-	EAL domain-containing protein	NA	NA	NA	NA
WP_174260717.1\|2982532_2985970_+	pyruvate carboxylase	NA	NA	NA	NA
WP_013626026.1\|2986089_2986794_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.6e-34	39.6
WP_013626027.1\|2986866_2989242_+	ABC transporter permease	NA	NA	NA	NA
WP_013626028.1\|2989324_2990641_+	biotin/lipoyl-binding protein	NA	NA	NA	NA
WP_013623800.1\|2990972_2991110_-	hypothetical protein	A0A2K9VH20	Faecalibacterium_phage	4.6e-07	67.5
WP_013623799.1\|2991109_2991298_-	hypothetical protein	A0A2K9VH42	Faecalibacterium_phage	1.1e-06	48.4
WP_013623798.1\|2991297_2993016_-	hypothetical protein	A0A2K9VH60	Faecalibacterium_phage	1.6e-218	66.3
WP_041444965.1\|2993092_2994211_-	group II intron reverse transcriptase domain-containing protein	H7BVN0	unidentified_phage	8.2e-110	54.0
WP_041444567.1\|2994479_2994827_-	diversity-generating retroelement protein Avd	A0A2K9VGX0	Faecalibacterium_phage	8.3e-29	61.8
WP_041444566.1\|2994795_2995065_-	hypothetical protein	A0A2K9VH74	Faecalibacterium_phage	2.4e-15	47.4
WP_148228165.1\|2995057_2995369_-	inorganic polyphosphate kinase	A0A2K9VGY9	Faecalibacterium_phage	5.3e-27	57.3
WP_013623793.1\|2995355_2995679_-	hypothetical protein	A0A2K9VGY5	Faecalibacterium_phage	7.2e-27	56.7
WP_013623791.1\|2996525_2997656_-\|plate	baseplate J/gp47 family protein	H7BVM7	unidentified_phage	2.0e-124	62.2
WP_013623790.1\|2997648_2998062_-	hypothetical protein	A0A2K9VH11	Faecalibacterium_phage	1.1e-32	50.0
WP_013623789.1\|2998061_2998346_-	hypothetical protein	NA	NA	NA	NA
WP_013623788.1\|2998363_2999119_-	serine/arginine repetitive matrix protein 2	H7BVM5	unidentified_phage	2.0e-99	68.1
WP_013623787.1\|2999135_2999729_-	hypothetical protein	A0A2K9VH28	Faecalibacterium_phage	4.0e-39	50.3
WP_013623786.1\|2999731_3002170_-\|tail	phage tail tape measure protein	A0A2K9VGW0	Faecalibacterium_phage	8.7e-181	50.4
WP_013623785.1\|3002221_3002461_+	hypothetical protein	NA	NA	NA	NA
WP_013623784.1\|3002477_3002666_-	hypothetical protein	A0A2K9VH64	Faecalibacterium_phage	1.1e-06	50.8
WP_013623783.1\|3002683_3003064_-	hypothetical protein	A0A2K9VGY3	Faecalibacterium_phage	1.3e-22	53.8
WP_013623782.1\|3003098_3003536_-	hypothetical protein	A0A2K9VGX6	Faecalibacterium_phage	8.8e-52	69.3
WP_013623781.1\|3003555_3004986_-	DUF2586 family protein	A0A2K9VH53	Faecalibacterium_phage	5.9e-145	56.8
WP_013623780.1\|3004986_3005205_-	hypothetical protein	NA	NA	NA	NA
WP_013623779.1\|3005194_3005707_-	hypothetical protein	A0A2K9VH02	Faecalibacterium_phage	1.5e-50	59.9
WP_013623778.1\|3005709_3006210_-	phage virion morphogenesis protein	A0A2K9VH22	Faecalibacterium_phage	3.1e-53	63.9
WP_148228056.1\|3006210_3006627_-	DUF1320 family protein	A0A2K9VH41	Faecalibacterium_phage	4.2e-43	64.3
WP_013623776.1\|3006674_3007562_-\|head	Mu-like prophage major head subunit gpT family protein	H7BVL8	unidentified_phage	6.3e-121	69.2
WP_013623775.1\|3007589_3008000_-	hypothetical protein	A0A2H4JCL7	uncultured_Caudovirales_phage	2.3e-38	62.5
WP_013623774.1\|3008001_3009057_-\|protease	phage protease	A0A2H4JAW3	uncultured_Caudovirales_phage	1.7e-125	64.7
WP_013623773.1\|3009194_3009938_-\|capsid	minor capsid protein	A0A2K9VGX3	Faecalibacterium_phage	8.7e-100	70.7
WP_013623772.1\|3009930_3011544_-	DUF935 domain-containing protein	A0A2H4JAU9	uncultured_Caudovirales_phage	6.5e-225	71.5
WP_013623771.1\|3011558_3013319_-\|terminase	phage terminase large subunit	A0A2H4JE58	uncultured_Caudovirales_phage	1.1e-275	79.3
WP_013623770.1\|3013311_3013872_-	DUF3486 family protein	H7BVL1	unidentified_phage	3.4e-64	69.9
WP_013623769.1\|3013871_3014186_-	hypothetical protein	A0A2H4JAV1	uncultured_Caudovirales_phage	1.9e-40	77.9
WP_013623768.1\|3014190_3014487_-	hypothetical protein	A0A2H4JGQ3	uncultured_Caudovirales_phage	2.9e-14	40.6
WP_013623767.1\|3014499_3014934_-	hypothetical protein	A0A2H4JFB1	uncultured_Caudovirales_phage	2.6e-35	62.4
WP_013623766.1\|3015054_3015384_-	hypothetical protein	A0A2H4JHA5	uncultured_Caudovirales_phage	2.1e-34	64.0
WP_013623765.1\|3015402_3016893_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4JCM7	uncultured_Caudovirales_phage	1.5e-114	47.4
WP_013623764.1\|3016905_3017292_-	hypothetical protein	A0A2K9VGW4	Faecalibacterium_phage	5.1e-27	55.1
WP_013623763.1\|3017266_3017737_-	regulatory protein GemA	A0A2H4JAV8	uncultured_Caudovirales_phage	1.3e-53	73.4
WP_013623762.1\|3017748_3018261_-	host-nuclease inhibitor Gam family protein	A0A2H4JE65	uncultured_Caudovirales_phage	1.1e-58	65.1
WP_013623761.1\|3018260_3018569_-	hypothetical protein	NA	NA	NA	NA
WP_041444955.1\|3018589_3019564_-	AAA family ATPase	A0A2H4JAW1	uncultured_Caudovirales_phage	5.4e-134	75.3
WP_013623759.1\|3019581_3021666_-\|transposase	Mu transposase C-terminal domain-containing protein	A0A2H4JGQ6	uncultured_Caudovirales_phage	2.0e-271	66.4
WP_013623758.1\|3021824_3022136_-	hypothetical protein	NA	NA	NA	NA
WP_013623757.1\|3022149_3022368_-	helix-turn-helix transcriptional regulator	A0A2H4JHB2	uncultured_Caudovirales_phage	7.3e-15	58.2
WP_148228055.1\|3022498_3022681_+	hypothetical protein	NA	NA	NA	NA
WP_013623755.1\|3022878_3023121_-	hypothetical protein	A0A2H4JCN6	uncultured_Caudovirales_phage	6.2e-07	56.2

DBSCAN-SWA_9

3153092 : 3197341

Faecalibacterium_phage(45.24%)

tail,protease,terminase,capsid,plate,head,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013626141.1\|3153092_3153539_-\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_013626142.1\|3153550_3154153_-	ATP-binding cassette domain-containing protein	NA	NA	NA	NA
WP_013626143.1\|3154142_3155072_-	ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	8.8e-09	28.4
WP_013626144.1\|3155641_3156706_+	hypothetical protein	NA	NA	NA	NA
WP_013626145.1\|3156808_3157441_-	DedA family protein	NA	NA	NA	NA
WP_013626146.1\|3157609_3159217_+	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_169312033.1\|3159267_3159864_-	radical SAM protein	A0A2L0HKI4	Mycobacterium_phage	1.5e-14	37.8
WP_013626148.1\|3159856_3160243_-	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_013626149.1\|3160248_3160944_-	7-cyano-7-deazaguanine synthase QueC	A0A1U9WRB5	Streptococcus_virus	1.2e-55	49.6
WP_013626150.1\|3161214_3161994_+	histidinol-phosphatase HisJ family protein	NA	NA	NA	NA
WP_013626151.1\|3162008_3163520_-	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_013626152.1\|3163522_3164440_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_148228155.1\|3164436_3164970_-	hypothetical protein	NA	NA	NA	NA
WP_013623800.1\|3165192_3165330_-	hypothetical protein	A0A2K9VH20	Faecalibacterium_phage	4.6e-07	67.5
WP_013623799.1\|3165329_3165518_-	hypothetical protein	A0A2K9VH42	Faecalibacterium_phage	1.1e-06	48.4
WP_013623798.1\|3165517_3167236_-	hypothetical protein	A0A2K9VH60	Faecalibacterium_phage	1.6e-218	66.3
WP_041444965.1\|3167312_3168431_-	group II intron reverse transcriptase domain-containing protein	H7BVN0	unidentified_phage	8.2e-110	54.0
WP_041444567.1\|3168699_3169047_-	diversity-generating retroelement protein Avd	A0A2K9VGX0	Faecalibacterium_phage	8.3e-29	61.8
WP_041444566.1\|3169015_3169285_-	hypothetical protein	A0A2K9VH74	Faecalibacterium_phage	2.4e-15	47.4
WP_148228165.1\|3169277_3169589_-	inorganic polyphosphate kinase	A0A2K9VGY9	Faecalibacterium_phage	5.3e-27	57.3
WP_013623793.1\|3169575_3169899_-	hypothetical protein	A0A2K9VGY5	Faecalibacterium_phage	7.2e-27	56.7
WP_013623791.1\|3170745_3171876_-\|plate	baseplate J/gp47 family protein	H7BVM7	unidentified_phage	2.0e-124	62.2
WP_013623790.1\|3171868_3172282_-	hypothetical protein	A0A2K9VH11	Faecalibacterium_phage	1.1e-32	50.0
WP_013623789.1\|3172281_3172566_-	hypothetical protein	NA	NA	NA	NA
WP_013623788.1\|3172583_3173339_-	serine/arginine repetitive matrix protein 2	H7BVM5	unidentified_phage	2.0e-99	68.1
WP_013623787.1\|3173355_3173949_-	hypothetical protein	A0A2K9VH28	Faecalibacterium_phage	4.0e-39	50.3
WP_013623786.1\|3173951_3176390_-\|tail	phage tail tape measure protein	A0A2K9VGW0	Faecalibacterium_phage	8.7e-181	50.4
WP_013623785.1\|3176441_3176681_+	hypothetical protein	NA	NA	NA	NA
WP_013623784.1\|3176697_3176886_-	hypothetical protein	A0A2K9VH64	Faecalibacterium_phage	1.1e-06	50.8
WP_013626153.1\|3176903_3177284_-	hypothetical protein	A0A2K9VGY3	Faecalibacterium_phage	3.4e-23	54.8
WP_013623782.1\|3177318_3177756_-	hypothetical protein	A0A2K9VGX6	Faecalibacterium_phage	8.8e-52	69.3
WP_013623781.1\|3177775_3179206_-	DUF2586 family protein	A0A2K9VH53	Faecalibacterium_phage	5.9e-145	56.8
WP_013623780.1\|3179206_3179425_-	hypothetical protein	NA	NA	NA	NA
WP_013623779.1\|3179414_3179927_-	hypothetical protein	A0A2K9VH02	Faecalibacterium_phage	1.5e-50	59.9
WP_013623778.1\|3179929_3180430_-	phage virion morphogenesis protein	A0A2K9VH22	Faecalibacterium_phage	3.1e-53	63.9
WP_148228056.1\|3180430_3180847_-	DUF1320 family protein	A0A2K9VH41	Faecalibacterium_phage	4.2e-43	64.3
WP_013623776.1\|3180894_3181782_-\|head	Mu-like prophage major head subunit gpT family protein	H7BVL8	unidentified_phage	6.3e-121	69.2
WP_013623775.1\|3181809_3182220_-	hypothetical protein	A0A2H4JCL7	uncultured_Caudovirales_phage	2.3e-38	62.5
WP_013623774.1\|3182221_3183277_-\|protease	phage protease	A0A2H4JAW3	uncultured_Caudovirales_phage	1.7e-125	64.7
WP_013623773.1\|3183414_3184158_-\|capsid	minor capsid protein	A0A2K9VGX3	Faecalibacterium_phage	8.7e-100	70.7
WP_013623772.1\|3184150_3185764_-	DUF935 domain-containing protein	A0A2H4JAU9	uncultured_Caudovirales_phage	6.5e-225	71.5
WP_013623771.1\|3185778_3187539_-\|terminase	phage terminase large subunit	A0A2H4JE58	uncultured_Caudovirales_phage	1.1e-275	79.3
WP_013623770.1\|3187531_3188092_-	DUF3486 family protein	H7BVL1	unidentified_phage	3.4e-64	69.9
WP_013623769.1\|3188091_3188406_-	hypothetical protein	A0A2H4JAV1	uncultured_Caudovirales_phage	1.9e-40	77.9
WP_013623768.1\|3188410_3188707_-	hypothetical protein	A0A2H4JGQ3	uncultured_Caudovirales_phage	2.9e-14	40.6
WP_013623767.1\|3188719_3189154_-	hypothetical protein	A0A2H4JFB1	uncultured_Caudovirales_phage	2.6e-35	62.4
WP_013623766.1\|3189274_3189604_-	hypothetical protein	A0A2H4JHA5	uncultured_Caudovirales_phage	2.1e-34	64.0
WP_013623765.1\|3189622_3191113_-	N-acetylmuramoyl-L-alanine amidase	A0A2H4JCM7	uncultured_Caudovirales_phage	1.5e-114	47.4
WP_013623764.1\|3191125_3191512_-	hypothetical protein	A0A2K9VGW4	Faecalibacterium_phage	5.1e-27	55.1
WP_013623763.1\|3191486_3191957_-	regulatory protein GemA	A0A2H4JAV8	uncultured_Caudovirales_phage	1.3e-53	73.4
WP_013623762.1\|3191968_3192481_-	host-nuclease inhibitor Gam family protein	A0A2H4JE65	uncultured_Caudovirales_phage	1.1e-58	65.1
WP_013623761.1\|3192480_3192789_-	hypothetical protein	NA	NA	NA	NA
WP_041444955.1\|3192809_3193784_-	AAA family ATPase	A0A2H4JAW1	uncultured_Caudovirales_phage	5.4e-134	75.3
WP_013623759.1\|3193801_3195886_-\|transposase	Mu transposase C-terminal domain-containing protein	A0A2H4JGQ6	uncultured_Caudovirales_phage	2.0e-271	66.4
WP_013623758.1\|3196044_3196356_-	hypothetical protein	NA	NA	NA	NA
WP_013623757.1\|3196369_3196588_-	helix-turn-helix transcriptional regulator	A0A2H4JHB2	uncultured_Caudovirales_phage	7.3e-15	58.2
WP_148228055.1\|3196718_3196901_+	hypothetical protein	NA	NA	NA	NA
WP_013623755.1\|3197098_3197341_-	hypothetical protein	A0A2H4JCN6	uncultured_Caudovirales_phage	6.2e-07	56.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_015172

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection