CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_015163	Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence	1 crisprs	NA	4	1
NC_015162	Deinococcus proteolyticus MRP plasmid pDEIPR02, complete sequence	0 crisprs	cas14j,csa3	0	1
NC_015161	Deinococcus proteolyticus MRP, complete sequence	1 crisprs	DEDDh,csa3,cas3	4	1
NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	1 crisprs	csa3	17	0
NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	3 crisprs	WYL,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,csa3	11	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_015161_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015161_1

385086-385358

Orphan

Consensus_repeat	Method
CGGAACATCCCCGCCTGCACGGGGAAAAC	PILER-CR
CGGAACATCCCCGCCTGCACGGGGAAAAC	CRISPRCasFinder
CGGAACATCCCCGCCTGCACGGGGAAAAC	CRT

4 spacers

The CRISPR arrays of NC_015161_1

>merge|NC_015161|1|385086-385358|PILER-CR,CRISPRCasFinder,CRT
CGGAACATCCCCGCCTGCACGGGGAAAACGTGATTCCGAAGTAGTCAGACAGCGAAACGAGCGGAACATCCCCGCCTGCACGGGGAAAACCGCCTCCCACATCGAAGAGTTGCTGGCCCGCACGGAACATCCCCGCCTGCACGGGGAAAACGGCGCCGCTGGCCGCTTTGCCGCTCTGCGCACCGGAACATCCCCGCCTGCACGGGGAAAACAAATTCTTCCCGAAAAAAGCCGACTGGGACAGCGGAACATCCCCGCCTGCACGGGGAAAAC

>NC_015161|1|1|385086-385358|PILER-CR
CGGAACATCCCCGCCTGCACGGGGAAAAC	GTGATTCCGAAGTAGTCAGACAGCGAAACGAG
CGGAACATCCCCGCCTGCACGGGGAAAAC	CGCCTCCCACATCGAAGAGTTGCTGGCCCGCA
CGGAACATCCCCGCCTGCACGGGGAAAAC	GGCGCCGCTGGCCGCTTTGCCGCTCTGCGCAC
CGGAACATCCCCGCCTGCACGGGGAAAAC	AAATTCTTCCCGAAAAAAGCCGACTGGGACAG
CGGAACATCCCCGCCTGCACGGGGAAAAC

>NC_015161|1|1|385086-385358|CRISPRCasFinder
CGGAACATCCCCGCCTGCACGGGGAAAAC	GTGATTCCGAAGTAGTCAGACAGCGAAACGAG
CGGAACATCCCCGCCTGCACGGGGAAAAC	CGCCTCCCACATCGAAGAGTTGCTGGCCCGCA
CGGAACATCCCCGCCTGCACGGGGAAAAC	GGCGCCGCTGGCCGCTTTGCCGCTCTGCGCAC
CGGAACATCCCCGCCTGCACGGGGAAAAC	AAATTCTTCCCGAAAAAAGCCGACTGGGACAG
CGGAACATCCCCGCCTGCACGGGGAAAAC

>NC_015161|1|1|385086-385358|CRT
CGGAACATCCCCGCCTGCACGGGGAAAAC	GTGATTCCGAAGTAGTCAGACAGCGAAACGAG
CGGAACATCCCCGCCTGCACGGGGAAAAC	CGCCTCCCACATCGAAGAGTTGCTGGCCCGCA
CGGAACATCCCCGCCTGCACGGGGAAAAC	GGCGCCGCTGGCCGCTTTGCCGCTCTGCGCAC
CGGAACATCCCCGCCTGCACGGGGAAAAC	AAATTCTTCCCGAAAAAAGCCGACTGGGACAG
CGGAACATCCCCGCCTGCACGGGGAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015161.1\|WP_083801523.1\|385447_387205_-\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|234861
NC_015161.1\|WP_041221895.1\|384217_385084_+\|aminoglycoside-6-adenylyltransferase	unknown	unknown	gnl\|CDD\|377357
NC_015161.1\|WP_013614148.1\|393760_394312_-\|ribosome-recycling-factor	unknown	unknown	gnl\|CDD\|178850
NC_015161.1\|WP_013614140.1\|382997_384167_-\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl\|CDD\|235472
NC_015161.1\|WP_013614138.1\|381372_381846_+\|hypothetical-protein	unknown	unknown	unknown
NC_015161.1\|WP_013614143.1\|387456_389325_+\|biosynthetic-type-acetolactate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|272915
NC_015161.1\|WP_013614146.1\|391095_392670_+\|threonine-ammonia-lyase,-biosynthetic	unknown	unknown	gnl\|CDD\|236417
NC_015161.1\|WP_013614137.1\|380471_381350_-\|sulfurtransferase	unknown	unknown	gnl\|CDD\|225450
NC_015161.1\|WP_013614144.1\|389321_389924_+\|acetolactate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|183365
NC_015161.1\|WP_013614150.1\|395276_396077_-\|elongation-factor-Ts	unknown	unknown	gnl\|CDD\|236491
NC_015161.1\|WP_148231755.1\|379134_380388_-\|divalent-metal-cation-transporter	unknown	unknown	gnl\|CDD\|224826
NC_015161.1\|WP_013614151.1\|396255_397056_-\|30S-ribosomal-protein-S2	unknown	unknown	gnl\|CDD\|235396
NC_015161.1\|WP_013614139.1\|381870_383001_-\|RIP-metalloprotease	unknown	unknown	gnl\|CDD\|223821
NC_015161.1\|WP_013614133.1\|376346_376799_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_015161.1\|WP_013614135.1\|377944_379066_+\|prephenate-dehydratase	unknown	unknown	gnl\|CDD\|223155
NC_015161.1\|WP_013614147.1\|392723_393557_-\|phosphatidate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|366491
NC_015161.1\|WP_013614145.1\|390003_391014_+\|ketol-acid-reductoisomerase	unknown	unknown	gnl\|CDD\|235491
NC_015161.1\|WP_013614149.1\|394376_395111_-\|UMP-kinase	unknown	unknown	gnl\|CDD\|239787
NC_015161.1\|WP_041221894.1\|375863_376313_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NC_015161.1\|WP_013614134.1\|376795_377917_+\|bifunctional-chorismate-mutase/prephenate-dehydrogenase	unknown	unknown	gnl\|CDD\|183035

Protein	Function_ID	Function_description	E-value
NC_015161.1\|WP_083801523.1\|385447_387205_-\|dihydroxy-acid-dehydratase	gnl\|CDD\|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
NC_015161.1\|WP_041221895.1\|384217_385084_+\|aminoglycoside-6-adenylyltransferase	gnl\|CDD\|377357	pfam04439, Adenyl_transf, Streptomycin adenylyltransferase. Also known as Aminoglycoside 6- adenylyltransferase (EC:2.7.7.-), this protein confers resistance to aminoglycoside antibiotics.	2.48344e-135
NC_015161.1\|WP_013614148.1\|393760_394312_-\|ribosome-recycling-factor	gnl\|CDD\|178850	PRK00083, frr, ribosome recycling factor; Reviewed.	1.03785e-97
NC_015161.1\|WP_013614140.1\|382997_384167_-\|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl\|CDD\|235472	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	3.70001e-170
NC_015161.1\|WP_013614143.1\|387456_389325_+\|biosynthetic-type-acetolactate-synthase-large-subunit	gnl\|CDD\|272915	TIGR00118, Probable_acetolactate_synthase_large_subunit, acetolactate synthase, large subunit, biosynthetic type. Two groups of proteins form acetolactate from two molecules of pyruvate. The type of acetolactate synthase described in this model also catalyzes the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, an early step in the branched chain amino acid biosynthesis; it is therefore also termed acetohydroxyacid synthase. In bacteria, this catalytic chain is associated with a smaller regulatory chain in an alpha2/beta2 heterotetramer. Acetolactate synthase is a thiamine pyrophosphate enzyme. In this type, FAD and Mg++ are also found. Several isozymes of this enzyme are found in E. coli K12, one of which contains a frameshift in the large subunit gene and is not expressed. [Amino acid biosynthesis, Pyruvate family].	0
NC_015161.1\|WP_013614146.1\|391095_392670_+\|threonine-ammonia-lyase,-biosynthetic	gnl\|CDD\|236417	PRK09224, PRK09224, threonine ammonia-lyase IlvA.	0
NC_015161.1\|WP_013614137.1\|380471_381350_-\|sulfurtransferase	gnl\|CDD\|225450	COG2897, SseA, Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism].	1.27334e-91
NC_015161.1\|WP_013614144.1\|389321_389924_+\|acetolactate-synthase-small-subunit	gnl\|CDD\|183365	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed.	1.12438e-68
NC_015161.1\|WP_013614150.1\|395276_396077_-\|elongation-factor-Ts	gnl\|CDD\|236491	PRK09377, tsf, elongation factor Ts; Provisional.	1.82421e-122
NC_015161.1\|WP_148231755.1\|379134_380388_-\|divalent-metal-cation-transporter	gnl\|CDD\|224826	COG1914, MntH, Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].	2.22111e-52
NC_015161.1\|WP_013614151.1\|396255_397056_-\|30S-ribosomal-protein-S2	gnl\|CDD\|235396	PRK05299, rpsB, 30S ribosomal protein S2; Provisional.	2.46666e-153
NC_015161.1\|WP_013614139.1\|381870_383001_-\|RIP-metalloprotease	gnl\|CDD\|223821	COG0750, COG0750, Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane].	2.42642e-58
NC_015161.1\|WP_013614133.1\|376346_376799_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.97076e-12
NC_015161.1\|WP_013614135.1\|377944_379066_+\|prephenate-dehydratase	gnl\|CDD\|223155	COG0077, PheA, Prephenate dehydratase [Amino acid transport and metabolism].	4.93803e-129
NC_015161.1\|WP_013614147.1\|392723_393557_-\|phosphatidate-cytidylyltransferase	gnl\|CDD\|366491	pfam01148, CTP_transf_1, Cytidylyltransferase family. The members of this family are integral membrane protein cytidylyltransferases. The family includes phosphatidate cytidylyltransferase EC:2.7.7.41 as well as Sec59 from yeast. Sec59 is a dolichol kinase EC:2.7.1.108.	8.03815e-61
NC_015161.1\|WP_013614145.1\|390003_391014_+\|ketol-acid-reductoisomerase	gnl\|CDD\|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	0
NC_015161.1\|WP_013614149.1\|394376_395111_-\|UMP-kinase	gnl\|CDD\|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	9.6385e-134
NC_015161.1\|WP_041221894.1\|375863_376313_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.28017e-10
NC_015161.1\|WP_013614134.1\|376795_377917_+\|bifunctional-chorismate-mutase/prephenate-dehydrogenase	gnl\|CDD\|183035	PRK11199, tyrA, bifunctional chorismate mutase/prephenate dehydrogenase; Provisional.	0

>NC_015161.1|WP_041221895.1|384217_385084_+|aminoglycoside-6-adenylyltransferase
MSETVLLRRVRAFAEADPRVRAAVLSGSRVNAAIRPDPFQDVDLTLYVRDLPSFTADHGWIDRFGERMILQIPVLMGAQDYDHASPILYLMQFMDGSRLDLGLVPLERRAEFPPESLSRVLLDKDGIFLALPEPHEGDYFPQPPSAQAFADCCNEFWWLAPYAVKGLRRGQLGYAKYHLDTLMRGELLRMLEWAFGCRTGWARNPGKFGARFAGVLPPDWLTRLDTTYAGADAGANWQALLAMTALFREAAAEVAACTGHVYPLQDDERVSAYLTRVGEEGVGQKGGL
>NC_015161.1|WP_013614140.1|382997_384167_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MESVKLTVLGSTGSIGTQTLEVARQRGWQVAALAGGRNLDLLETQVQEWQPAAVAVAEERYAQAKARFSQTEILPLAELAVREADVVVNAIGGLPGLSPTRAALEAGRAVALATKEAMVTAAPLIWAAAQQGGGSVVPIDSEHTGIYQCLVGERLSDVAELILTASGGPFRLGPADLSTVTPGQALNHPSWNMGQKITVDSATLLNKGLEVMECAALYGLPLSQVRVVVHPQSIMHAAVRWVDGNLSANVGPTDMRLSIAYAIEAAAAGGMTRPGEVVGARRGQGAAEHLAWPLEGRWEFHAPDLERFPALGLAYRAGEAGGLLPAALNAADEVAVPAFLAGNIGFLDIPRVIEQVLNECPREPLDWATLESVQAWATRRAQELCGGRP
>NC_015161.1|WP_013614139.1|381870_383001_-|RIP-metalloprotease
MNPMQAIAAALSPQGIVWTLLLLSVITALHELGHYWAARKQSVKVDSFSVGMGPVLLRRQWRGTEWRLSLLPIGGYVQIDGMAPEEAPDGTLRHPSTGFAALPPLGRIGVLLAGPLVNLLLAIGLMTATFSALGVTANDRVRVGEVIAGSPAERLGLRAGDDIVALDGQDIPEQAEIAGKAGPGYLLLGELLKEAGPHTLTVQRTGEAEQRQLAFDWTPTVNGERQLLGIRYGPGSQPVSVPQALGRSLQTTAEAVPLVVNSFAGLLGEMFSLDLKGEETDDVGGPIRITETVSRAAALNGWALVQIATLLNLSLAVFNLLPIPGLDGGRIALVLIEMLRGRPLTFQQEQSVTAAGFLFVMLLMAFVLVRDVTRFF
>NC_015161.1|WP_013614138.1|381372_381846_+|hypothetical-protein
MTNLPPVCVSAELWAALMGASSPADVVLSDGGLPPDLPVVLPAALQADIIGGVRAPAPIWTFAYEDTDQIVSSPGHRWQVLIRLSPSQPQLLSDLQGSLEVQGFELEKTGTYLLWGVRQDPPQSVEVLLPRGAGFLFLRVSDIQPQAAWAQRPGDAG
>NC_015161.1|WP_013614137.1|380471_381350_-|sulfurtransferase
MTQSDLPTPLVSAEWLQAHLHDPRLRLLDCRFDLRDALLGRMAYLESHLPGAVYADLEMNLSGPVSESGAGGRHPLPEPEALAAWLGEQGTGNDSWVVCYDAGGAQGYYAARAWWLLRWLGHTQVAVLDGGLAAWQALGGELTDAEPQNAPATFTAQVQPGYVATAEDVAALPTGTLLIDSRTPERYRGETEPVDRRAGHIPGAVNRNWLGALDESGRFRNAEAQAERLGAGDGQPTVTYCGSGVSATPNLLARELAGVPLGPDNRLYAGSWSDWVSDEGRPTTTGNTDTAE
>NC_015161.1|WP_148231755.1|379134_380388_-|divalent-metal-cation-transporter
MQAAVPSSTWQTRLAALGPGIMMASAAIGGSHIVSSAQAGALFGWQLAGLILLTNLLKYPFFRFGPQYTMESGQSLVEGYARKGRGYLWVFFILCAVSSVISTAGVGLLSAVILNSMLPAGFALSGPVMASVMMLVVWVLLVAGHYKALDGITKLIVIGLTVATVAATFIAASKGSNMVPGFVEPSPWNLATLPFLVALVGWMPAPIEISAINSMWIKAKQKISPANYADTIFDFNVGYVTSAVLAIFFVAMGALVQYGNGEKLEPASAAYISQLVQMYGSTIGEWSKPVIAFIAFMCMFGTTITVVDGYARASGEALRLLRGDPELKTRDISLWITGISVIGLAIILLMQNQLAGLLKFAMTSAFVTAPIFAWLNLSLVSGERHLSGTLRALAYAGLAFLVGFTLLFLANLLGLLG
>NC_015161.1|WP_013614135.1|377944_379066_+|prephenate-dehydratase
MSDQPGRPDPTSESLAAALAPHRERIDAIDAQLLDLLSQRAAEARAIGTLKGTAAVYRPEREAQVLARIAALNAGPLHENAVRRIFREIMSECLALERPLTVTYLGPQGTFTEQAARRHFGGAAQLASCATIDEALREVEARQADYAVVPVENSSEGAVNRTLDLLPATPLRACGEVTLRIHHCLMSPGEDAAAVARIYAHPQALAQCHEYLTRHLPAAERLPVSSNAEAARLAAQSGQAHVAALGPGAAAGLYGLNVLEQNIEDDPSNTTRFLVLGHASPGPSGQDRTTLVVAAPQAEHAGAMHRLLEPFSRLGISMTRLESRPVRGGLWQYVFFIDIEGHAQDRDVAQALAEMRERATFLKVVGSFPRAVS
>NC_015161.1|WP_013614134.1|376795_377917_+|bifunctional-chorismate-mutase/prephenate-dehydrogenase
MTPPELAALREQIDANDRELLQLLRQRVELARQVGDVKRAQGLPIYVPEREAALLDARRAEAQALGLSPDLAEDVLRRCMRESYVQETGHSVGVRPGLRVVVVGGGGRLGRRFVQAFRESGYEVAVLERGDWDRAAELVQGAGLVLVSVPIHDTAAVMAQLPPLPPGCLLADLTSVKAAPMQAMLAAHSGPVLGLHPMFGPDVLTFAKEVTVFCRGRGEPGEVDWLLEQLRLWGLRLHAAQPEEHDRHMGLIQAMRHATAYAYGLNLSRERPQLDELLALSSPIYRLELMMVGRLFAQDPELYYDIIQSQRQHLELIRDYHATLADVIGLLERDDRDAFTQRFCEVREFFGPLGEQFLNESRVMLAQSKDRAG
>NC_015161.1|WP_013614133.1|376346_376799_+|GNAT-family-N-acetyltransferase
MLHLRHATLDDLDTLSELFDEYRVWYGQPSDPAGARDFLRERRLLGESVVLLALVGDRPAGFTQLYRSFSSVRMRRLWILNDLFVRAGFRGQRVGVALLDAARDLAVQSGAAGVVLETAGDNLAAQRLYDRYGFQRSSGVHYLLRVGGER
>NC_015161.1|WP_041221894.1|375863_376313_+|GNAT-family-N-acetyltransferase
MSWSVRPVTRADAHTVARHRLPDVPPDHAAVQTYAEWLPGALEREIYFGWLAETAHGVIGGAGLTLLEWGPTREDPQPWRGRVVNVWTHPRWRRQGVARQLVMHALAAAAARGVQVLSLSTTSAGRPLYGSLGFGTASAEMVRRGPRQG
>NC_015161.1|WP_083801523.1|385447_387205_-|dihydroxy-acid-dehydratase
MDKGQPNTGPREQARASGKGDAGASGGGRKLNWNSHHVTAGDEKAPNRAMLRAVGFTDADFDKPIVGVAHAQSNITPCNNGLGELAGAITGAIQAAGGMPQVYGTITVSDGISMGTEGMKCSLVSREVIADSIEAVSRAQSHDGVIVVGGCDKNMPGAMIGLARLNIPAIFVYGGTIKPGHHGGQDLTIVSVFEAVGAYGAGKMSREDFEAIERKACPGNGSCGGMYTANTMSSAFEAMGMSLPYSSTMSAVDAEKADSAAESGRTLIRLIEQDLRPRDILTKEAFENAITVIMAVGGSTNAVLHLMAIAHAMQVELTLDDFERIRERTPVFCDLKPSGQYVAADLHAVGGIPRVMKMLLKAGLLHGDCLTVTGRTVAENLADVPDVPDAGQDVIRPFDQPLYADGHLAILRGNLAPSGSVAKISGLKSIKITGPARVFDSEEACMEAIMGDRIQPGDVLVIRYEGPRGGPGMREMLSPTSAIIGKGLGDSVGLITDGRFSGGTFGLVVGHVAPEAYVGGPIALVHEGDTIELDAEKLELNLHVDDAELQRRRSEWVQPAPNYTRGVLAKYARLVSGAERGAVTD
>NC_015161.1|WP_013614143.1|387456_389325_+|biosynthetic-type-acetolactate-synthase-large-subunit
MTSPPDSPQPGSPQPDFRQPGSPQPGSRQTDIRQTGAGALWASLEAHGVHTVFGYPGGAIMPVYDALTFFPQIRHILGRHEQGCIHAAEGWAKATGELGVVLATSGPGATNLVTGLADAMLDSVPLLAITGNVASFLMGTDAFQEADITGITLPVTKHNYVVRSAEELPGVIAEAIHIARSGRPGPVLVDIPKDVQLAACEYDPASLRPHPPLPPREPDAAALAAARELLAQATRPVMMVGGGALDAAAEVTALARAWNIPVITTLMGLGAFPASDPLWLGMPGMHGSVAANRAISEADVLLGIGLRFDDRVTGRVRDFAPQARIIHVDLDAAELGKIVATHCPVRAGAAQVARALSVQAPPERPPRTAWLEQLAEWKGRGHHPQDWGAAQAVRQVVARLRPDDILSSDVGQHQMLAAQLARFERPRRWLNSGGLGTMGFGFPAAIGAALAEPEVVSMVIAGDGGFQMTAQELATLKHAGIHNVKICIINNSYLGMVRQWQELFHGERYSEVELGPSNPDFLKLADAYGVPGWRAEDSAGLEAALDGWLNHPGSALLEVVVPSQHHVFPMVPAGASLAEMLETGPVRASTEVSDLPAGVEAPGDDMEAVPIMALDARSGGQA
>NC_015161.1|WP_013614144.1|389321_389924_+|acetolactate-synthase-small-subunit
MSGEHLVSALVRDEPRVLTRITALFGRRGYNIKSLSVGATETPGVSRMTFVVGGERGVVEQAMRQLEKLHDVLQIIDHSREKYVDRELVLLKVRVDKDTRLEVRQMAEDFRARIVDAGRQALMFEVTGDEGKITAFIEQMRPFGILETMRTGRAALIRGSNADIASHVYGGESQALAALASGLRPVPQPREAASRDGGEQ
>NC_015161.1|WP_013614145.1|390003_391014_+|ketol-acid-reductoisomerase
MTAKMYYDADVSMQPLADKVVAVIGYGSQAHAHAQNMHDSGVNVIIGLREGSGSRAKAEQAGLQVMSIPEATQAADVVALLIPDEEQPKVYAEQMAPHLTAGKTLLFGHGFNVHFGRITPPAEVDVMLVAPKGPGHMLRRVYKEGAGMPGIFAVGQDASGHARDTALAYARAIGCTRAGVLETTFKEETETDLFGEQAVLCGGVTQLIQSGFETLVEAGYQPEIAYFETLHEVKLIVDLIYEKGFEGMRHSISNTAEFGDYVTGPRIVNARTKEEMKQVLADIQSGAFADRFTADYQGGFSHMNEQRGKMRGHQLETVGKELRRKMPFINQEELEV
>NC_015161.1|WP_013614146.1|391095_392670_+|threonine-ammonia-lyase,-biosynthetic
MSAPPSQPPSPAGTSFASATPFGMDLVRDVLNSRVYDVAVRTPLQPAPRLSERLGQRVYFKREDQQPVFSFKLRGAYNRMAQLSEAERAAGVICASAGNHAQGVAYSAQQLGVRAVIVMPVTTPDIKVRACRDRGAEVILYGDSFSDAAAHAFEVQAERGLTFIHPFDDPAVIAGQGTVGLELLSQVQEGAYTVFVPVGGGGLIAGVAAFLGTLNPAVRIVGVEPEDSAAMSLSIQAGERVWLKQVGLFVDGVAVKQVGEHTFALCREYVHDWVTVTTDEVCAAIKDVFDDTRSIMEPAGALAVAGLKRYARQLEGTGQTLVALTCGANMNFDRLRHVAERAEVGEQKEAVLAVTIPEQPGAFVRFCGALGPLAVTEFNYRYAPRQDARIFVGVQLQRPGDRAAIVQRLEEAGYPVLDLTDDEVAGVHVRHMVGGRAPEALHERLYSFNFPERPGALLEFLLRLGQEWNISLFHYRNHGSDYGRVLAGIQVPLQDLSRFREALAGVGYDFTEQTANPAYRTFLQ
>NC_015161.1|WP_013614147.1|392723_393557_-|phosphatidate-cytidylyltransferase
METLSSRVSTAVIGFLVVSAIVYLGWWAMLPALLLVSVMGLFEYVRMLDYNDIDVRRGTLAVFGSAILIASLPMLPDTPWPGGSWREAVLTVAVGYLLVIEVIRPGERPLERIVYSLFGLLYIPWLLGYFLMLRYTPDSELGLLYFALPLLATFAADIGGFFGGYTFGRRKLAPEISPAKTVEGAISGLLFSFVVIAVLTEFVYPIWTPAEAFLYAMLVASASQLGDLAESLIKRALKTKDSGTSLPGHGGFLDRLDSLLFAVPATYLYLHISLLGG
>NC_015161.1|WP_013614148.1|393760_394312_-|ribosome-recycling-factor
MSDTNSIYKDARERMGKSIEALESNLGVLRTGRANPGILKKVMVEYFGSTMPIDQVASINAPDARTLTVTPWDRGALNPIEKAIRDSDLGLNPNNKGDMIFISIPALTEERRKEMVKNAKSYAEEARISIRNVRKSALDEVKKLDDLGEDEVKRAEAEVQKITDEYVKKVDEVFDRKEAEILG
>NC_015161.1|WP_013614149.1|394376_395111_-|UMP-kinase
MFKRVLLKLSGEFLSDDSGFGINPDTTRQLAQLIISALDGTEVELAVVIGGGNLWRGARNGKGMDPATADYIGMLGTVMNAMALQDAMEAAGKPTRVMSAIAMQAVAEPYIRRRAIRHLEKDRVVIFGGGNGAPFFTTDTTSTLRALEIGADVVLMAKNKVDGVYDKDPQKHADAVRFDELTHMDVVEQRLAVMDATALTLCMDKGLPIVVFDIFQEGNLRRLFEGQRVGTLISTPGAGTAAQG
>NC_015161.1|WP_013614150.1|395276_396077_-|elongation-factor-Ts
MMESIKKLREMTGAGMMDVKKALSDAEGNEEKAVALLRERGIVKAAKKADREAKEGLVRFVVDGGKAAMVEVNSETDFVARNADFQAIVEQLAQAALKAGTSDLDTFREFQMDSGEKVGDAVAALSGKIGENIVLNRVAYLEGDNLAGYVHSNGKIGVLTDIQGGTPEQAKDVALHIAAEKPEYLTRDEVNAEDIEKEREVLTNKAIAEGKPENMVEKIVGGQIGKFYEERVLPEQKFVKDNSLTVEKYLGEAKVSKFIRFEVGSK
>NC_015161.1|WP_013614151.1|396255_397056_-|30S-ribosomal-protein-S2
MSYISMKQLLEAGVHFGHETKRWNPKFGRFIFGERNGIFIIDLQKTLKQVDRSFDYIKDLAEKGGTILFVGTKKQAQEIVELEARRTGMPFVTSRWLGGMLTNYRTIRTRVERLDELDELFESGRINDRPKAERVQLGTERDRLQRFVGGIRKMNRLPDAIFVIDPTKEVIAVKEANKLGIPVIALADTDSDPDVIDYIVPGNDDAIRSIQLITHRIGDLLVEARGADEDVEQGEERVEESNADIEAAEAGESVENVQVTSSQGRS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP019460	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed3, complete sequence	13683-13714	6	0.812
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP019460	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed3, complete sequence	29160-29191	6	0.812
NC_015161_1	1.1\|385115\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385115-385146	32	MG945797	UNVERIFIED: Microviridae sp. isolate 4494-1801, complete genome	2944-2975	8	0.75
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	2243987-2244018	8	0.75
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	LR606150	Rhizobium sp. Q54 genome assembly, plasmid: 7	24946-24977	8	0.75
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NZ_CP049906	Diaphorobacter sp. HDW4B plasmid unnamed1, complete sequence	224414-224445	8	0.75
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP046321	Gordonia bronchialis strain FDAARGOS_676 plasmid unnamed1, complete sequence	4479-4510	8	0.75
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NC_013442	Gordonia bronchialis DSM 43247 plasmid pGBRO01, complete sequence	232-263	8	0.75
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NC_014213	Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence	298958-298989	9	0.719
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	1403283-1403314	9	0.719
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	1420389-1420420	9	0.719
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	1555954-1555985	9	0.719
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	20574-20605	9	0.719
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	99670-99701	9	0.719
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	1205107-1205138	9	0.719
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	544286-544317	9	0.719
NC_015161_1	1.2\|385176\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385176-385207	32	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	1257836-1257867	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP025081	Klebsiella pneumoniae strain SGH10 plasmid pSGH10, complete sequence	117751-117782	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP031258	Klebsiella quasipneumoniae strain L22 plasmid pL22-1, complete sequence	23652-23683	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052163	Klebsiella pneumoniae strain F16KP0082 plasmid pF16KP0082-1, complete sequence	60048-60079	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP030924	Klebsiella pneumoniae subsp. pneumoniae strain KC-Pl-HB1 plasmid pKC-Pl-HB1, complete sequence	34916-34947	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP026022	Klebsiella pneumoniae strain 11492 plasmid p11492-CTXM, complete sequence	177481-177512	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP014011	Klebsiella pneumoniae subsp. pneumoniae strain RJF999 plasmid pRJF999, complete sequence	14453-14484	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP037743	Klebsiella pneumoniae strain ST23 plasmid pDHQP1701672_hv, complete sequence	115342-115373	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052159	Klebsiella pneumoniae strain F16KP0084 plasmid pF16KP0084-1, complete sequence	117455-117486	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	MN200128	Klebsiella pneumoniae strain 17ZR-91 plasmid p17ZR-91-Vir-RC, complete sequence	92562-92593	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	MN200130	Escherichia coli strain EC600 plasmid p17ZR-91-TC1, complete sequence	92545-92576	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	MN543581	Klebsiella pneumoniae strain PM48TC plasmid pPM48TC_fusion, complete sequence	98930-98961	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	MN543585	Klebsiella pneumoniae strain GH27TC plasmid pGH27TC_fusion, complete sequence	91655-91686	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	MN543575	Klebsiella pneumoniae strain GH44TC plasmid pGH44TC_fusion, complete sequence	107778-107809	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	MN543576	Klebsiella pneumoniae strain GH44TC plasmid pGH44TC_vir, complete sequence	102321-102352	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052144	Klebsiella pneumoniae strain F17KP0012 plasmid pF17KP0012-1, complete sequence	118006-118037	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052363	Klebsiella pneumoniae strain D16KP0122 plasmid pD16KP0122-1, complete sequence	108508-108539	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP019049	Klebsiella pneumoniae subsp. pneumoniae strain RJA166 plasmid pRJA166b, complete sequence	226066-226097	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP024708	Klebsiella pneumoniae strain cr-hvkp3 plasmid pPUTH1, complete sequence	203664-203695	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP034776	Klebsiella pneumoniae strain 18CPO060 plasmid phvKP060, complete sequence	155031-155062	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052357	Klebsiella pneumoniae strain D16KP0144 plasmid pD16KP0144-1, complete sequence	118782-118813	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_LR134257	Klebsiella aerogenes strain NCTC9644 plasmid 4, complete sequence	172067-172098	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP027063	Klebsiella variicola strain WCHKV030666 plasmid pVir_030666, complete sequence	99838-99869	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052445	Klebsiella pneumoniae strain C16KP0098 plasmid pC16KP0098-2, complete sequence	108032-108063	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_FO834905	Klebsiella pneumoniae strain Kp52.145 plasmid II, complete sequence	24909-24940	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP014009	Klebsiella pneumoniae subsp. pneumoniae strain RJF293 plasmid pRJF293, complete sequence	124534-124565	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP006989	Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence	259365-259396	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	LR134211	Klebsiella aerogenes strain NCTC418 genome assembly, plasmid: 2	156154-156185	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NC_005249	Klebsiella pneumoniae CG43 plasmid pLVPK, complete sequence	91168-91199	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP036191	Klebsiella pneumoniae strain BA34918 plasmid pvirulence_VBA34918, complete sequence	5216-5247	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NC_006625	Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 plasmid pK2044, complete sequence	17132-17163	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP019161	Klebsiella pneumoniae strain GN-2 plasmid pGN-2, complete sequence	19483-19514	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052563	Klebsiella pneumoniae strain A16KP0135 plasmid pA16KP0135-1, complete sequence	116674-116705	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_AP019666	Klebsiella pneumoniae strain TA6363 plasmid pTMTA63631, complete sequence	99165-99196	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP035906	Klebsiella pneumoniae strain BA4656 plasmid unnamed1, complete sequence	156677-156708	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	MF943217	Klebsiella pneumoniae strain WCHKP13F2 plasmid pVir_WCHKP13F2, complete sequence	53773-53804	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052190	Klebsiella pneumoniae strain F16KP0019 plasmid pF16KP0019-1, complete sequence	118006-118037	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP030270	Klebsiella pneumoniae subsp. pneumoniae strain SC-7 plasmid pSC7-vir, complete sequence	116181-116212	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP035384	Klebsiella pneumoniae strain AP8555 plasmid pAP855, complete sequence	246073-246104	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP023723	Klebsiella pneumoniae strain TVGHCRE225 plasmid unnamed1, complete sequence	104563-104594	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP047678	Klebsiella pneumoniae subsp. pneumoniae strain KUH-KPNHVF1 plasmid unnamed, complete sequence	17108-17139	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP026166	Klebsiella pneumoniae strain F81 plasmid pF81_2, complete sequence	109421-109452	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP047676	Klebsiella pneumoniae subsp. pneumoniae strain KUH-KPNHVL1 plasmid unnamed, complete sequence	17108-17139	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052304	Klebsiella pneumoniae strain E16KP0172 plasmid pE16KP0172-1, complete sequence	119333-119364	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP052037	Klebsiella pneumoniae strain KPN41053 plasmid pKPN41953, complete sequence	132340-132371	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052204	Klebsiella pneumoniae strain F16KP0002 plasmid pF16KP0002-1, complete sequence	118007-118038	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP023135	Klebsiella pneumoniae subsp. pneumoniae strain KpvK54 plasmid pKpvK54, complete sequence	27402-27433	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP007642	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence	247693-247724	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052178	Klebsiella pneumoniae strain F16KP0045 plasmid pF16KP0045-1, complete sequence	79545-79576	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP028390	Klebsiella pneumoniae strain WCHKP13F2 plasmid pVir_095132, complete sequence	105005-105036	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP045692	Klebsiella pneumoniae strain TK421 plasmid pTK421_2, complete sequence	111807-111838	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP034083	Klebsiella pneumoniae subsp. pneumoniae strain R210-2 plasmid pR210-2-vir, complete sequence	117747-117778	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP042975	Klebsiella pneumoniae strain KPN55602 plasmid pK55602_1, complete sequence	93688-93719	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP026012	Klebsiella pneumoniae strain K2044 plasmid pK2044, complete sequence	206990-207021	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP026024	Klebsiella pneumoniae strain 11420 plasmid p11420-HVKP, complete sequence	17614-17645	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_AP019549	Klebsiella pneumoniae strain THC11 plasmid pTHC11-1, complete sequence	93082-93113	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_LR792629	Klebsiella pneumoniae isolate SB5881 plasmid SB5881_II	24877-24908	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP041024	Klebsiella pneumoniae strain KP1692 plasmid pKP1692, complete sequence	28458-28489	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052259	Klebsiella pneumoniae strain E16KP0290 plasmid pE16KP0290-1, complete sequence	29067-29098	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP054064	Klebsiella pneumoniae strain WSHvKP plasmid pSWHvKp, complete sequence	102017-102048	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP026587	Klebsiella pneumoniae strain NUHL30457 plasmid p1, complete sequence	207358-207389	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_LR745046	Klebsiella pneumoniae isolate Kpn2166 plasmid pVIR_Kpn2166	24995-25026	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_LR745043	Klebsiella pneumoniae isolate Klebsiella pneumoniae kpn154 plasmid pVIR_Kpn154	55881-55912	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	CP052495	Klebsiella pneumoniae strain B17KP0067 plasmid pB17KP0067-1, complete sequence	118783-118814	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_MK715436	Klebsiella pneumoniae subsp. pneumoniae strain SCNJ1 plasmid pVir-SCNJ1, complete sequence	120528-120559	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_MN058044	Klebsiella pneumoniae strain KP1677 plasmid pKP1677, complete sequence	79700-79731	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NC_017541	Klebsiella pneumoniae KCTC 2242 plasmid pKCTC2242, complete sequence	186225-186256	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP032356	Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_Vir, complete sequence	100412-100443	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_MH255828	Klebsiella pneumoniae subsp. pneumoniae strain SH9 plasmid pSH9-VIR, complete sequence	60079-60110	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_MF398271	Klebsiella pneumoniae subsp. pneumoniae strain 70-2 plasmid pKP70-2, complete sequence	126757-126788	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_CP016815	Klebsiella pneumoniae strain ED23 plasmid unamed, complete sequence	17044-17075	9	0.719
NC_015161_1	1.3\|385237\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385237-385268	32	NZ_MG053312	Klebsiella pneumoniae strain KP267 plasmid pVir-CR-HvKP267, complete sequence	229290-229321	9	0.719
NC_015161_1	1.4\|385298\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385298-385329	32	NZ_CP025513	Neorhizobium sp. SOG26 plasmid unnamed2, complete sequence	668354-668385	9	0.719
NC_015161_1	1.4\|385298\|32\|NC_015161\|PILER-CR,CRISPRCasFinder,CRT	385298-385329	32	MH616766	Microviridae sp. isolate ctba71, complete genome	4132-4163	10	0.688

1. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019460 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.812

ggcgccgctggccgctttgccgc-tctgcgcac	CRISPR spacer
ggcgccgctggccgcgctgccgcgtccgcggt-	Protospacer
*************** .****** **.***

2. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019460 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.812

ggcgccgctggccgctttgccgc-tctgcgcac	CRISPR spacer
ggcgccgctggccgcgctgccgcgtccgcggt-	Protospacer
*************** .****** **.***

3. spacer 1.1|385115|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to MG945797 (UNVERIFIED: Microviridae sp. isolate 4494-1801, complete genome) position: , mismatch: 8, identity: 0.75

gtgattccgaagtagtcagacagcgaaacgag	CRISPR spacer
gggatgccgaagtagtcagccagcgttcctac	Protospacer
* *** ************* *****   * *

4. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 8, identity: 0.75

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
gccgatcaacatcgacgagttgcgggcccgca	Protospacer
  *  .* ******* ******* ********

5. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to LR606150 (Rhizobium sp. Q54 genome assembly, plasmid: 7) position: , mismatch: 8, identity: 0.75

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
gccgatcaacatcgacgagttgcgggcccgca	Protospacer
  *  .* ******* ******* ********

6. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049906 (Diaphorobacter sp. HDW4B plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
gcccttccacatcgaagagttgcgggtcaggg	Protospacer
  ***.***************** **.* * .

7. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046321 (Gordonia bronchialis strain FDAARGOS_676 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
ggcgccgctggccgcgttcccgcacctccacc	Protospacer
*************** ** **** *. *   *

8. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NC_013442 (Gordonia bronchialis DSM 43247 plasmid pGBRO01, complete sequence) position: , mismatch: 8, identity: 0.75

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
ggcgccgctggccgcgttcccgcacctccacc	Protospacer
*************** ** **** *. *   *

9. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NC_014213 (Meiothermus silvanus DSM 9946 plasmid pMESIL01, complete sequence) position: , mismatch: 9, identity: 0.719

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
caaaacccacatcgaggagttgctggccaaac	Protospacer
*.   **********.************ .

10. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 9, identity: 0.719

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
ctttgcccacatcgaagagtcactggccgcga	Protospacer
* .. ***************..******   *

11. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 9, identity: 0.719

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
ctttgcccacatcgaagagtcactggccgcga	Protospacer
* .. ***************..******   *

12. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
ctttgcccacatcgaagagtcactggccgcga	Protospacer
* .. ***************..******   *

13. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
ctttgcccacatcgaagagtcactggccgcga	Protospacer
* .. ***************..******   *

14. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
ctttgcccacatcgaagagtcactggccgcga	Protospacer
* .. ***************..******   *

15. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
ctttgcccacatcgaagagtcactggccgcga	Protospacer
* .. ***************..******   *

16. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
ctttgcccacatcgaagagtcactggccgcga	Protospacer
* .. ***************..******   *

17. spacer 1.2|385176|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 9, identity: 0.719

cgcctcccacatcgaagagttgctggcccgca	CRISPR spacer
ctttgcccacatcgaagagtcactggccgcga	Protospacer
* .. ***************..******   *

18. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025081 (Klebsiella pneumoniae strain SGH10 plasmid pSGH10, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

19. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031258 (Klebsiella quasipneumoniae strain L22 plasmid pL22-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

20. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052163 (Klebsiella pneumoniae strain F16KP0082 plasmid pF16KP0082-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

21. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030924 (Klebsiella pneumoniae subsp. pneumoniae strain KC-Pl-HB1 plasmid pKC-Pl-HB1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

22. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026022 (Klebsiella pneumoniae strain 11492 plasmid p11492-CTXM, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

23. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014011 (Klebsiella pneumoniae subsp. pneumoniae strain RJF999 plasmid pRJF999, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

24. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP037743 (Klebsiella pneumoniae strain ST23 plasmid pDHQP1701672_hv, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

25. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052159 (Klebsiella pneumoniae strain F16KP0084 plasmid pF16KP0084-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

26. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to MN200128 (Klebsiella pneumoniae strain 17ZR-91 plasmid p17ZR-91-Vir-RC, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

27. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to MN200130 (Escherichia coli strain EC600 plasmid p17ZR-91-TC1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

28. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to MN543581 (Klebsiella pneumoniae strain PM48TC plasmid pPM48TC_fusion, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

29. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to MN543585 (Klebsiella pneumoniae strain GH27TC plasmid pGH27TC_fusion, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

30. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to MN543575 (Klebsiella pneumoniae strain GH44TC plasmid pGH44TC_fusion, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

31. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to MN543576 (Klebsiella pneumoniae strain GH44TC plasmid pGH44TC_vir, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

32. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052144 (Klebsiella pneumoniae strain F17KP0012 plasmid pF17KP0012-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

33. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052363 (Klebsiella pneumoniae strain D16KP0122 plasmid pD16KP0122-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

34. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019049 (Klebsiella pneumoniae subsp. pneumoniae strain RJA166 plasmid pRJA166b, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

35. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024708 (Klebsiella pneumoniae strain cr-hvkp3 plasmid pPUTH1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

36. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034776 (Klebsiella pneumoniae strain 18CPO060 plasmid phvKP060, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

37. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052357 (Klebsiella pneumoniae strain D16KP0144 plasmid pD16KP0144-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

38. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134257 (Klebsiella aerogenes strain NCTC9644 plasmid 4, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

39. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027063 (Klebsiella variicola strain WCHKV030666 plasmid pVir_030666, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

40. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052445 (Klebsiella pneumoniae strain C16KP0098 plasmid pC16KP0098-2, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

41. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_FO834905 (Klebsiella pneumoniae strain Kp52.145 plasmid II, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

42. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014009 (Klebsiella pneumoniae subsp. pneumoniae strain RJF293 plasmid pRJF293, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

43. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006989 (Rhizobium sp. IE4771 plasmid pRetIE4771c, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
ccggccgccggccgctttgccgatctcctggc	Protospacer
   *****.************* *** *  .*

44. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to LR134211 (Klebsiella aerogenes strain NCTC418 genome assembly, plasmid: 2) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

45. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NC_005249 (Klebsiella pneumoniae CG43 plasmid pLVPK, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

46. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP036191 (Klebsiella pneumoniae strain BA34918 plasmid pvirulence_VBA34918, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

47. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NC_006625 (Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 plasmid pK2044, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

48. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019161 (Klebsiella pneumoniae strain GN-2 plasmid pGN-2, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

49. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052563 (Klebsiella pneumoniae strain A16KP0135 plasmid pA16KP0135-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

50. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019666 (Klebsiella pneumoniae strain TA6363 plasmid pTMTA63631, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

51. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035906 (Klebsiella pneumoniae strain BA4656 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

52. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to MF943217 (Klebsiella pneumoniae strain WCHKP13F2 plasmid pVir_WCHKP13F2, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

53. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052190 (Klebsiella pneumoniae strain F16KP0019 plasmid pF16KP0019-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

54. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030270 (Klebsiella pneumoniae subsp. pneumoniae strain SC-7 plasmid pSC7-vir, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

55. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP035384 (Klebsiella pneumoniae strain AP8555 plasmid pAP855, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

56. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023723 (Klebsiella pneumoniae strain TVGHCRE225 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

57. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047678 (Klebsiella pneumoniae subsp. pneumoniae strain KUH-KPNHVF1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

58. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026166 (Klebsiella pneumoniae strain F81 plasmid pF81_2, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

59. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047676 (Klebsiella pneumoniae subsp. pneumoniae strain KUH-KPNHVL1 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

60. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052304 (Klebsiella pneumoniae strain E16KP0172 plasmid pE16KP0172-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

61. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP052037 (Klebsiella pneumoniae strain KPN41053 plasmid pKPN41953, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

62. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052204 (Klebsiella pneumoniae strain F16KP0002 plasmid pF16KP0002-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

63. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP023135 (Klebsiella pneumoniae subsp. pneumoniae strain KpvK54 plasmid pKpvK54, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

64. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP007642 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803a, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
ccggccgccggccgctttgccgatctcctggc	Protospacer
   *****.************* *** *  .*

65. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052178 (Klebsiella pneumoniae strain F16KP0045 plasmid pF16KP0045-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

66. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP028390 (Klebsiella pneumoniae strain WCHKP13F2 plasmid pVir_095132, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

67. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045692 (Klebsiella pneumoniae strain TK421 plasmid pTK421_2, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

68. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034083 (Klebsiella pneumoniae subsp. pneumoniae strain R210-2 plasmid pR210-2-vir, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

69. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042975 (Klebsiella pneumoniae strain KPN55602 plasmid pK55602_1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

70. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026012 (Klebsiella pneumoniae strain K2044 plasmid pK2044, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

71. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026024 (Klebsiella pneumoniae strain 11420 plasmid p11420-HVKP, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

72. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019549 (Klebsiella pneumoniae strain THC11 plasmid pTHC11-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

73. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR792629 (Klebsiella pneumoniae isolate SB5881 plasmid SB5881_II) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

74. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041024 (Klebsiella pneumoniae strain KP1692 plasmid pKP1692, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

75. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052259 (Klebsiella pneumoniae strain E16KP0290 plasmid pE16KP0290-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

76. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054064 (Klebsiella pneumoniae strain WSHvKP plasmid pSWHvKp, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

77. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026587 (Klebsiella pneumoniae strain NUHL30457 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

78. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR745046 (Klebsiella pneumoniae isolate Kpn2166 plasmid pVIR_Kpn2166) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

79. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR745043 (Klebsiella pneumoniae isolate Klebsiella pneumoniae kpn154 plasmid pVIR_Kpn154) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

80. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to CP052495 (Klebsiella pneumoniae strain B17KP0067 plasmid pB17KP0067-1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

81. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MK715436 (Klebsiella pneumoniae subsp. pneumoniae strain SCNJ1 plasmid pVir-SCNJ1, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

82. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MN058044 (Klebsiella pneumoniae strain KP1677 plasmid pKP1677, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

83. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NC_017541 (Klebsiella pneumoniae KCTC 2242 plasmid pKCTC2242, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

84. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032356 (Klebsiella variicola strain 15WZ-82 plasmid p15WZ-82_Vir, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

85. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MH255828 (Klebsiella pneumoniae subsp. pneumoniae strain SH9 plasmid pSH9-VIR, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

86. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MF398271 (Klebsiella pneumoniae subsp. pneumoniae strain 70-2 plasmid pKP70-2, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

87. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016815 (Klebsiella pneumoniae strain ED23 plasmid unamed, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

88. spacer 1.3|385237|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG053312 (Klebsiella pneumoniae strain KP267 plasmid pVir-CR-HvKP267, complete sequence) position: , mismatch: 9, identity: 0.719

ggcgccgctggccgctttgccgctctgcgcac	CRISPR spacer
caggccggaggccgctttgccgctctccccgg	Protospacer
 . ****  ***************** * *.

89. spacer 1.4|385298|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025513 (Neorhizobium sp. SOG26 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

aaattcttcccgaaaaaagccgactgggacag	CRISPR spacer
aaaatcttcccgaaaaaagcggaaggtcgctt	Protospacer
*** **************** **  *  .*

90. spacer 1.4|385298|32|NC_015161|PILER-CR,CRISPRCasFinder,CRT matches to MH616766 (Microviridae sp. isolate ctba71, complete genome) position: , mismatch: 10, identity: 0.688

aaattcttcccgaaaaaagccgactgggacag	CRISPR spacer
gaattcttccctaaaaaaggcgaccttttaaa	Protospacer
.********** ******* ****.     *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1704512 : 1711893

Staphylococcus_phage(66.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013615340.1\|1704512_1705439_+	30S ribosomal protein S6--L-glutamate ligase	A0A1D7SA11	Synechococcus_phage	1.6e-39	33.9
WP_013615341.1\|1705501_1706704_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	2.3e-102	48.9
WP_013615342.1\|1706703_1707378_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.1e-27	35.0
WP_083801580.1\|1707377_1708475_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.5e-34	37.2
WP_013615344.1\|1708911_1709460_-	RNA 2'-phosphotransferase	A0A2H4IBJ2	Erwinia_phage	5.0e-28	40.2
WP_013615345.1\|1709456_1710467_-	DUF4357 domain-containing protein	NA	NA	NA	NA
WP_013615346.1\|1710666_1711893_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.8e-118	55.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_015162

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

78685 : 118657

Streptococcus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013615857.1\|78685_79852_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A068A1P5	Thermus_phage	1.4e-104	52.5
WP_148231990.1\|80531_82031_+	replication initiator protein A	NA	NA	NA	NA
WP_013615860.1\|82058_83084_+	hypothetical protein	F8J1D6	Lactobacillus_phage	9.7e-33	30.8
WP_013615861.1\|83116_83644_+	hypothetical protein	NA	NA	NA	NA
WP_013615862.1\|83791_84400_+	hypothetical protein	NA	NA	NA	NA
WP_013615863.1\|84396_85080_+	hypothetical protein	NA	NA	NA	NA
WP_013615864.1\|85279_86218_+	NAD(P)/FAD-dependent oxidoreductase	A0A2K9L4X0	Tupanvirus	3.3e-11	23.5
WP_013615865.1\|86300_87200_+	hypothetical protein	NA	NA	NA	NA
WP_013615866.1\|87199_87829_+	hypothetical protein	NA	NA	NA	NA
WP_013615867.1\|88028_88778_+	hypothetical protein	NA	NA	NA	NA
WP_041223067.1\|88774_89191_+	hypothetical protein	NA	NA	NA	NA
WP_013615869.1\|89392_89761_+	hypothetical protein	NA	NA	NA	NA
WP_013615870.1\|89757_90354_+	hypothetical protein	NA	NA	NA	NA
WP_013615871.1\|90350_90554_+	hypothetical protein	NA	NA	NA	NA
WP_013615872.1\|90599_91601_+	hypothetical protein	NA	NA	NA	NA
WP_013615873.1\|91597_92527_+	hypothetical protein	NA	NA	NA	NA
WP_148231991.1\|92567_93029_+	hypothetical protein	NA	NA	NA	NA
WP_013615875.1\|93019_93262_+	hypothetical protein	NA	NA	NA	NA
WP_013615876.1\|93305_93971_+	hypothetical protein	NA	NA	NA	NA
WP_013615877.1\|94067_94496_+	DUF3846 domain-containing protein	NA	NA	NA	NA
WP_013615878.1\|94513_95017_+	hypothetical protein	NA	NA	NA	NA
WP_013615879.1\|95087_97727_-	UvrD-helicase domain-containing protein	A0A0S0NAE3	Pseudomonas_phage	2.2e-28	26.0
WP_013615880.1\|97766_98291_-	GreA/GreB family elongation factor	NA	NA	NA	NA
WP_013615881.1\|98295_98676_-	hypothetical protein	NA	NA	NA	NA
WP_013615883.1\|99146_99956_+	hypothetical protein	NA	NA	NA	NA
WP_013615884.1\|99955_100702_+	hypothetical protein	NA	NA	NA	NA
WP_013615885.1\|100760_101588_+	hypothetical protein	NA	NA	NA	NA
WP_013615886.1\|101620_102340_+	hypothetical protein	NA	NA	NA	NA
WP_013615887.1\|102438_102735_+	hypothetical protein	NA	NA	NA	NA
WP_013615888.1\|102731_102959_+	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_013615889.1\|102955_103528_+	hypothetical protein	NA	NA	NA	NA
WP_013615890.1\|103524_103803_+	hypothetical protein	NA	NA	NA	NA
WP_013615891.1\|103864_104368_+	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_013615892.1\|104364_105000_+	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_148231993.1\|105025_105697_-	hypothetical protein	NA	NA	NA	NA
WP_169310710.1\|105999_106431_-	hypothetical protein	NA	NA	NA	NA
WP_169310663.1\|107400_107769_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_169310664.1\|107801_108260_+\|transposase	transposase	NA	NA	NA	NA
WP_083801595.1\|108418_108613_+	hypothetical protein	NA	NA	NA	NA
WP_169310711.1\|108587_108797_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_083801594.1\|108916_109216_-\|transposase	transposase	NA	NA	NA	NA
WP_013615894.1\|109865_110516_-	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_013615895.1\|110563_112750_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.8e-129	38.7
WP_013615896.1\|112751_113351_+	isoprenylcysteine carboxylmethyltransferase family protein	NA	NA	NA	NA
WP_013615897.1\|113366_113633_+	glutaredoxin family protein	NA	NA	NA	NA
WP_013615898.1\|113625_114531_+	cation transporter	NA	NA	NA	NA
WP_126352310.1\|114620_115196_+	SCO family protein	NA	NA	NA	NA
WP_013615900.1\|115192_115594_+	winged helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	9.7e-13	38.6
WP_126352311.1\|115667_116012_+	hypothetical protein	NA	NA	NA	NA
WP_041223109.1\|116013_116346_-	YnfA family protein	A0A2H4JF35	uncultured_Caudovirales_phage	1.2e-11	41.6
WP_013615903.1\|116411_116657_-	DUF2171 domain-containing protein	NA	NA	NA	NA
WP_126352280.1\|116738_117438_+\|transposase	IS1 family transposase	A0A077SLN4	Escherichia_phage	6.0e-26	36.2
WP_013615904.1\|117568_118657_-\|transposase	IS701 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_015163

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_015163_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015163_1

46414-46666

Orphan

Consensus_repeat	Method
CGACGACATAGTTGAGCGATT	CRT

4 spacers

The CRISPR arrays of NC_015163_1

>merge|NC_015163|1|46414-46666|CRT
CGACGACATAGTTGAGCGATTCGGCCGATTTATCGACGACATAGTTGAGCGATTGTGCTTTCTCTGCCGACGACATAGTTGAGCGATTCGGGGGTAGGGCCACGACATAGTTGAGCGATTCTCGACGACATAGTTGAGCGATTGGCCACGACATAGTTGAGCGATTCGGGGGTAAGGCTACGACATAGTTGAACGATTTGGCCCCTCCACCGACGACATAGTCGAGCGATTACGACGACATAGTTGAGCGAAA

>NC_015163|1|1|46414-46666|CRT
CGACGACATAGTTGAGCGATT	CGGCCGATTTATCGACGACATAGTTGAGCGATTGTGCTTTCTCTGC
CGACGACATAGTTGAGCGATT	CGGGGGTAGGGCCACGACATAGTTGAGCGATTCT
CGACGACATAGTTGAGCGATT	GGCCACGACATAGTTGAGCGATTCGGGGGTAAGG
CTACGACATAGTTGAACGATT	TGGCCCCTCCACCGACGACATAGTCGAGCGATTA
CGACGACATAGTTGAGCGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_015163.1\|WP_013616025.1\|39015_39681_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_015163.1\|WP_013616030.1\|46786_48157_+\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|370826
NC_015163.1\|WP_013616026.1\|39684_40800_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|274368
NC_015163.1\|WP_013616034.1\|51758_52985_-\|DUF790-family-protein	unknown	unknown	gnl\|CDD\|368530
NC_015163.1\|WP_013616038.1\|59100_59766_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_015163.1\|WP_148232024.1\|41994_42177_+\|hypothetical-protein	unknown	unknown	unknown
NC_015163.1\|WP_148232023.1\|38458_38944_+\|DUF305-domain-containing-protein	unknown	unknown	gnl\|CDD\|367619
NC_015163.1\|WP_148232029.1\|36113_36953_-\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NC_015163.1\|WP_169310718.1\|54383_54623_-\|hypothetical-protein	unknown	unknown	unknown
NC_015163.1\|WP_013616027.1\|41400_41802_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|153434
NC_015163.1\|WP_013616028.1\|42216_42930_-\|IS6-family-transposase	unknown	unknown	gnl\|CDD\|225853
NC_015163.1\|WP_049775355.1\|52971_54345_-\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|223989
NC_015163.1\|WP_013616032.1\|49143_49911_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379293
NC_015163.1\|WP_013616031.1\|48223_49147_-\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|319251
NC_015163.1\|WP_013616033.1\|50442_51561_-\|hypothetical-protein	unknown	unknown	unknown
NC_015163.1\|WP_126352314.1\|58477_59077_+\|DUF305-domain-containing-protein	unknown	unknown	gnl\|CDD\|367619
NC_015163.1\|WP_013616021.1\|36985_37273_-\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_015163.1\|WP_041223169.1\|44550_45138_-\|DUF305-domain-containing-protein	unknown	unknown	gnl\|CDD\|367619
NC_015163.1\|WP_169310719.1\|56765_57296_-\|hypothetical-protein	unknown	unknown	unknown
NC_015163.1\|WP_013616022.1\|37718_38258_+\|CueP-family-metal-binding-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015163.1\|WP_013616025.1\|39015_39681_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.5272e-84
NC_015163.1\|WP_013616030.1\|46786_48157_+\|replication-initiator-protein-A	gnl\|CDD\|370826	pfam10134, RPA, Replication initiator protein A. Members of this family of bacterial proteins are single-stranded DNA binding proteins that are involved in DNA replication, repair and recombination.	5.34976e-23
NC_015163.1\|WP_013616026.1\|39684_40800_+\|HAMP-domain-containing-protein	gnl\|CDD\|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	1.82052e-66
NC_015163.1\|WP_013616034.1\|51758_52985_-\|DUF790-family-protein	gnl\|CDD\|368530	pfam05626, DUF790, Protein of unknown function (DUF790). This family consists of several hypothetical archaeal proteins of unknown function.	0
NC_015163.1\|WP_013616038.1\|59100_59766_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.29495e-83
NC_015163.1\|WP_148232023.1\|38458_38944_+\|DUF305-domain-containing-protein	gnl\|CDD\|367619	pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.	5.13476e-33
NC_015163.1\|WP_148232029.1\|36113_36953_-\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	2.30023e-10
NC_015163.1\|WP_013616027.1\|41400_41802_-\|hypothetical-protein	gnl\|CDD\|153434	cd08026, DUF326, Cysteine-rich 4 helical bundle widely conserved in bacteria. This functionally uncharacterized protein forms a 4-helical bundle with a bromodomain-like topology. It is present in major bacterial lineages and contains highly conserved cysteines in a repeated pattern, whose sidechains appear buried. Some family members have been (mis)annotated as putative ferredoxins.	1.97254e-15
NC_015163.1\|WP_013616028.1\|42216_42930_-\|IS6-family-transposase	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.03626e-49
NC_015163.1\|WP_049775355.1\|52971_54345_-\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	5.9236e-105
NC_015163.1\|WP_013616032.1\|49143_49911_-\|AAA-family-ATPase	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	7.92654e-42
NC_015163.1\|WP_013616031.1\|48223_49147_-\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|319251	cd16393, SPO0J_N, Thermus thermophilus stage 0 sporulation protein J-like N-terminal domain, ParB family member. Spo0J (stage 0 sporulation protein J) is a ParB family member, a critical component of the ParABS-type bacterial chromosome segregation system. The Spo0J N-terminal region acts in protein-protein interaction and is adjacent to the DNA-binding domain that binds to parS sites. Two Spo0J bind per parS site, and Spo0J interacts with neighbors via the N-terminal domain to form oligomers via an Arginine-rich patch (RRXR). This superfamily represents the N-terminal domain of ParB, a DNA-binding component of the prokaryotic parABS partitioning system. parABS contributes to the efficient segregation of chromosomes and low-copy number plasmids to daughter cells during prokaryotic cell division. The process includes the parA (Walker box) ATPase, the ParB DNA-binding protein and a parS cis-acting DNA sites. Binding of ParB to centromere-like parS sites is followed by non-specific binding to DNA ("spreading", which has been implicated in gene silencing in plasmid P1) and oligomerization of additional ParB molecules near the parS sites. It has been proposed that ParB-ParB cross-linking compacts the DNA, binds to parA via the N-terminal region, and leads to parA separating the ParB-parS complexes and the recruitment of the SMC (structural maintenance of chromosomes) complexes. The ParB N-terminal domain of Bacillus subtilis and other species contains a Arginine-rich ParB Box II with residues essential for bridging of the ParB-parS complexes. The arginine-rich ParB Box II consensus (I[VIL]AGERR[FYW]RA[AS] identified in several species is partially conserved with this family and related families. Mutations within the basic columns particularly debilitate spreading from the parS sites and impair SMC recruitment. The C-terminal domain contains a HTH DNA-binding motif and is the primary homo-dimerization domain, and binds to parS DNA sites. Additional homo-dimerization contacts are found along the N-terminal domain, but dimerization of the N-terminus may only occur after concentration at ParB-parS foci.	1.49946e-41
NC_015163.1\|WP_126352314.1\|58477_59077_+\|DUF305-domain-containing-protein	gnl\|CDD\|367619	pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.	1.01664e-28
NC_015163.1\|WP_013616021.1\|36985_37273_-\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	6.82573e-12
NC_015163.1\|WP_041223169.1\|44550_45138_-\|DUF305-domain-containing-protein	gnl\|CDD\|367619	pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.	7.14555e-36

>NC_015163.1|WP_041223169.1|44550_45138_-|DUF305-domain-containing-protein
MVKPKKTILLTATAVLLAFPLAQAQGMNHSSMHMSDMSSMDLSGMKKLQGKAFDRAFMSAMIPHHQAAVDMAKAVLPVSKDATVKTWANAVIKDQNREINQMSAWLKANGGTDANMAKMMSGSMQGMASMVKSSKTPDVAFVQGMIPHHASAVDMANLALQQGSDQTVLKLARDIVKAQAQEMYDYRQWLKKRGL
>NC_015163.1|WP_013616028.1|42216_42930_-|IS6-family-transposase
MPADPKPYRHRFPKSIIQHAVWLYHRFTLSYRDIEELLFQRGIQVSHETIRDWCDKFGPNLTKELKKREPQRGSRWHLDEVCVKIKGVKQWLWRAVDEHGAVLDVLLQEHRDTEAAKTFFATLLITNEVPTAIHTDKLGSYSAAIRELPELHGAEHREVISTARCNNLVEQSHRPTRSQERSQKGFKSISRAQNFLDLHARTSNLHQHTRTTVTAETRRSNQKAAFQTWNEVALLAA
>NC_015163.1|WP_148232024.1|41994_42177_+|hypothetical-protein
MKTRFGVLTILLASNVVAQDTMPGMNMGTPTAPSIHDQHHPAASPNISSLPETPIRVLSG
>NC_015163.1|WP_013616027.1|41400_41802_-|hypothetical-protein
MNTISAMLSTHPKPGKFDSGSLAECISACLECTGCCTICADACLNETEHLAHLTKCITLNGQCADVCAATAGVLSRVGQGDEAVIRAQLQACVAACQACAQECESHAKMGMKHCEICAECCRRCEAACQKLLA
>NC_015163.1|WP_013616026.1|39684_40800_+|HAMP-domain-containing-protein
MRFFPRLLLSHLLVILLAVLGMFLSAELVAPNFYREHVNRMAAMMTGMIGTANHELRLDLETGLRTTLTSALLASLPLAGGVAIVTAWLVSRRLGRSVQLLDEGSRALAQGNYARRLPETGQDELSDLAHNFNVMAGALEQVEQGRVELIGNVAHELRAPLAALRGYADAMQDGVMTPEHAAQSISREIGAMDRLVRDLSLVSRVEAGKVELHLKAIDPQGLLQIMRERFATPFEDKGVQLQITDAVLPQIKADEERTLQVLTNLLSNALRHTPAGGKVSVTVQTEAALLKFNVQDTGTGIPAEHLPRIFERFYRADPARSRNEGGSGVGLTIAKGLVEAMGGEMWVVSNVGQGSVFSFTLPTFTVLKSNS
>NC_015163.1|WP_013616025.1|39015_39681_+|response-regulator-transcription-factor
MPNILIVDDDPAILEILRAYLKAEGHTVLEACDGYSAREQLPRADLAILDWMLPGVSGVDLAREARASGLTLPILMLTARGEEEDKLRGLDFGVDDYVVKPFSPREVVARVRALLRRVGVQEEIAVGDLRIDLRGHSASLSGERLELSKLEFDLLSALAQHPGMAWPRERLLERVWGSDFPGTERVVDVHITGLRKKLGDTSDTPRFIETVRGVGYRFREE
>NC_015163.1|WP_148232023.1|38458_38944_+|DUF305-domain-containing-protein
MMGGMSGMSEMMGGMNAQNIDRNFITMMIPHHQSAIDMSQLILKTTKDPQVKTWATNIIRDQQREINQMQAMVGQFGGPMQGMGQQMDQMMGDMTTPINQATNKDKAFVEGMIPHHGMAVMMANHLLMQSKNPVMQKMGRDIITAQAQEIYEFQQYLNKTK
>NC_015163.1|WP_013616022.1|37718_38258_+|CueP-family-metal-binding-protein
MQKQTLLTIGFIPLSSLALALALAQSSSPLPDQLKGVSPLKAMQLANSWKGTAVKSFVDDSAVQFTFPDGRQQSVPLPAKQMVIAIAPYVNQTHPCKTHFMSGCQGELVNTPVKVQVTNAAGKTVINRTVKTLPNGFLELWLDRNQTYNVTLSAQGRSVKGQLQTLKGSDTCVTTLRLQ
>NC_015163.1|WP_013616021.1|36985_37273_-|transposase
MGKQRKTWSPELKEQIVLAVLSGERTIAEAAREYEVSESLIHTWRAQFLEAGRARLQGARPDAAQKKLEKEVQQLKAIIADKELSLYIAKKIRGL
>NC_015163.1|WP_148232029.1|36113_36953_-|DDE-type-integrase/transposase/recombinase
MLGDHPKLSLSRFAGEVERPYHVLRDARQNAQRSAQRTERRQHILEVVRFKALEEPLSGYRLIYQALQQDAQQPSPGLHTVRRHMAELKVQRPVPRKKRRPSACPTSIVLWPAGRRVQVDATRLSLPDGICWAYLVLDVESRALLHIEVVRNLSASSAVTALQRGVYVLHHLGIHEQLLIMTDGGSDFTSGAFQAACQELGNWVRAKVSRKGGMGILERLNRTFKYDGVFREELTNIAQLRAFSTKFKNWYNSERRHSSLGYAYPWVKLLEATESSNVA
>NC_015163.1|WP_013616030.1|46786_48157_+|replication-initiator-protein-A
MPLNEKTAATQIDELNLSQLNLISAVDKAENSEWEVSYEHGGRVVQIRCEALPKYSVPHGLDNDVSAALINLFMDSGMPEDGRFTISATALLRLCGWHNTGHYHATLKTSLERLHTSSYTVSGGWRDHPRGRWTHAKFHFIESLQFTTAGSGQFDERTVIKGRLADALIESLRGGYVKPLDSEFMLSLSRPRTRVLYRILDGARYDPENLEQYRDQYEVGLLAWAEQCRIPNSVPGNVRRALSGPHEELVERGYLRSVTISGRGKQQRIRYEFNENFIQVNPALLQRLQGYGIADGVARRLSNELGSAALHAHMDRFDWLVRTGVLVVKKSRAAALMHLIQHPDEYPYPLQAPEKAEKAPAKAKAARNPEPLLEPPSVAQEFAKLSVEEAAERGISRLGFHFRQDLSPLLLDQLRQAFLDGRLSPAAVLEDAMAAVARMKKAEFLEALREKLELRH
>NC_015163.1|WP_013616031.1|48223_49147_-|ParB/RepB/Spo0J-family-partition-protein
MSARKPSSQLAAIVAAAQSNVEGIRQNEGERRAARQLPIGQISPSPYQARRDFSNLASLVEDIREHGVLQPILVRPLGEDRFELIAGERRWRASQEAGLTKIPAVVREFTDREALLVGLAENLQREDLNAYEIARAVIELAAAELEQPADKVRKALSSKRPEEEVLRAMDAALGLLNKDMTLRTYQRHYLPLLRLDPHLIEAIEHGASYAAVLLIRGVEKRQQQQWLPKLVSGEWSRSDLEEALRKHRSAAKAKPVPHEEYDWGSKAQEVQQGLTEERLRQLDGRQQRKARRLLEQLAELLGESTVR
>NC_015163.1|WP_013616032.1|49143_49911_-|AAA-family-ATPase
MTQQARTQVIMTFIHAGGAGKTTTTRDIGAELARRGYRILLVDLDPQANLTYWLGVVGLPVEQTIVPVLRDGAPLPTPQHAFGMDIIPSHLDLAQVDVLLAALHNPEGRLKKAIDKVRASGDYDFILLDAPPSLGKLTANGANAADWLIVPLPASRKGLDAIAGVREAIERYSDTNENLEVAMYLVTQATHNNTSRDVQDAYSQLIGEQLAGPIIHRPAIYGDAQVESRPIEPKQKEAHAEIAAAVDALLSRVQA
>NC_015163.1|WP_013616033.1|50442_51561_-|hypothetical-protein
MPLLFVHGVAIRQEDAPEFKTLHSLTSGVDWTAISALLREYVAPVMRPDAPQDVSLEWLYWGDLGATYRGGGRFRGTFEPESPPVPHPLEASAQAQAQWLEDRLLPQTPAALWPATIEAAALTAEDQTVRLLAAELSEPARSEVLLAAVEARRQNHTTLRSTPQLSALLLRWEERRRGRLQQAFRGVRRPLEDFGPIFLGDALTYFTLRGTPEQPGPVLERVLAALQQADATAKRSGEPLVVLSHSLGGQLVYDVLSSVVPARPDLADLRVDLWCAVGSQLGLFKELGLMLEDHFPASTNHADASPLLNHLGYLWNVWSYGDLLSFRAEGSIPSAHDAPFPLGGQVQDEHLAYFHQPHFYAALAAKLRSLTR
>NC_015163.1|WP_013616034.1|51758_52985_-|DUF790-family-protein
MLPTELLSFGVKGGVVTPRRLKPTEGNLQLAETLTGTFEEHLGRPRFELDEALAEIERGRRDFKVIRGLAHLLTQQSTFEAAGGVPPERVREKVFALAQEGIPSRRRTAQVLETARRELGINDSQNLSHLLYADLPDQQTMTQAPQLSPTELIQRYDLANAQGMLYRAYSLVITARRNQPARYKQLLQYTKFFGLMLTVEGDPKFGFTLTMDGPSSLLGSTTRYGLAMAKFLPALLHVTKWDLTAEIKARKDLAWVDPKDDVWTFELTSEDGYVSHYREPEEHDSALEAGFAERFSRLDTEWTLEREVDLVPVPGGVILPDFRLEHPDGRSVLVEIVGYWRPEYLRKKFELLRKSGRDDVIVCVSERLNLDKAGVKHSDFRGRTVWFKGVLKPQDVLALAEAGVAKEA
>NC_015163.1|WP_049775355.1|52971_54345_-|DEAD/DEAH-box-helicase-family-protein
MQEPPEVVGDHFTWDQRSQSYRARGMDYRDIALGLREAGIAFEDRAKAFGELNLTYTREITPYPHQAAALTAWKQAGRRGVVVLPTGAGKTLVAQLALKDTPRSALICVPTLDLLQQWYSGLLAAFPDTNIGLLGGGSHDESPLLVSTYDSAAIYAEELAGRYATLIFDEVHHLPSDFHRSVAEMCIAPYRLGLTATPKRSDGREADLGRLVGPVVYSVSPDELSGDTLADYREVIIRVKLSPTEQQRYDECMALRNEYLRMTGIRIGSIEGWQQFIRSSGTLEGRRAFLAHREAKSIAYGTEGKLRVLEEILAQHPSERTIIFTNDNATVYRISREFLIPSITHQTPTKERHTLLERFRAGEYRLLVTSRVLNEGVDVPEASVAVVLSGTSTEREHIQRLGRILRRAQGKKAVLYEVITEGTTEERISQQRRGQWQPAGEAGPDIGPIWETLNAPD
>NC_015163.1|WP_169310718.1|54383_54623_-|hypothetical-protein
MAMSDQKERLSLSGNPEPEVVDILWMDDRHVHVLCSDGDEVTWPIGVMVEHLQGVQRLQIRVIDGDLDLVPLYTEVVCA
>NC_015163.1|WP_169310719.1|56765_57296_-|hypothetical-protein
MCQHSSGRLSLSSHFHKPPCFIFFCDLDNVSFNLSGTESDVDVCVVMTDVFWGDFTEAPGENLESYGFLPSNRMYEDDRELVRRALVQKFGSSGFTSGKKAFDVHGVAGSRVDADVVPAWLFRSFHGRGIYGQPIAREGIAFWTTDGKQVINVPEQHIIMGRQKTTQPTTALLITA
>NC_015163.1|WP_126352314.1|58477_59077_+|DUF305-domain-containing-protein
MAGGGQPTVTTSVNAQSPMNQMPAMGQMMDHSQMHMGQQMGAGDMMSMMGGLETMSGQKLDRAFLSMMIPHHQAAVEMSQEILKTTQDAQVKAWAEGIIAAQKTEISQMTTMLQPYGGPDIGMAAEMDGMMTGMVSEIQQAKDKDAAFVKGMIPHHGSAIMMANIALLKSENPEVLALARDITRAQAQEIYDFQMYLLQ
>NC_015163.1|WP_013616038.1|59100_59766_+|response-regulator-transcription-factor
MSQVLIVDDDPAILEILQAYLVAEGHTVLSASDGFGAREGLPRADLAIIDWMLPGVSGMDLVREARAADMQLPILMLTARGEEEDKLRGLDFGVDDYVVKPFSPREVMARVRALLRRVGVREEVSIGDLSIDLRSHTASLSGLPLELSKLEFDLLTALAQHPGMAWTRERLLERVWGSDFLGTERVVDVHITGLRKKLGDTSDNPQFIETVRGVGYRFREE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015163_1	1.1\|46435\|46\|NC_015163\|CRT	46435-46480	46	NC_015163	Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence	46435-46480	0	1.0
NC_015163_1	1.2\|46502\|34\|NC_015163\|CRT	46502-46535	34	NC_015163	Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence	46502-46535	0	1.0
NC_015163_1	1.3\|46557\|34\|NC_015163\|CRT	46557-46590	34	NC_015163	Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence	46557-46590	0	1.0
NC_015163_1	1.4\|46612\|34\|NC_015163\|CRT	46612-46645	34	NC_015163	Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence	46612-46645	0	1.0
NC_015163_1	1.4\|46612\|34\|NC_015163\|CRT	46612-46645	34	NC_015163	Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence	46402-46435	2	0.941
NC_015163_1	1.3\|46557\|34\|NC_015163\|CRT	46557-46590	34	NC_015163	Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence	46479-46512	3	0.912
NC_015163_1	1.2\|46502\|34\|NC_015163\|CRT	46502-46535	34	NC_015163	Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence	46548-46581	7	0.794
NC_015163_1	1.3\|46557\|34\|NC_015163\|CRT	46557-46590	34	NC_015163	Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence	46511-46544	8	0.765

1. spacer 1.1|46435|46|NC_015163|CRT matches to NC_015163 (Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence) position: , mismatch: 0, identity: 1.0

cggccgatttatcgacgacatagttgagcgattgtgctttctctgc	CRISPR spacer
cggccgatttatcgacgacatagttgagcgattgtgctttctctgc	Protospacer
**********************************************

2. spacer 1.2|46502|34|NC_015163|CRT matches to NC_015163 (Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence) position: , mismatch: 0, identity: 1.0

cgggggtagggccacgacatagttgagcgattct	CRISPR spacer
cgggggtagggccacgacatagttgagcgattct	Protospacer
**********************************

3. spacer 1.3|46557|34|NC_015163|CRT matches to NC_015163 (Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence) position: , mismatch: 0, identity: 1.0

ggccacgacatagttgagcgattcgggggtaagg	CRISPR spacer
ggccacgacatagttgagcgattcgggggtaagg	Protospacer
**********************************

4. spacer 1.4|46612|34|NC_015163|CRT matches to NC_015163 (Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence) position: , mismatch: 0, identity: 1.0

tggcccctccaccgacgacatagtcgagcgatta	CRISPR spacer
tggcccctccaccgacgacatagtcgagcgatta	Protospacer
**********************************

5. spacer 1.4|46612|34|NC_015163|CRT matches to NC_015163 (Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence) position: , mismatch: 2, identity: 0.941

tggcccctccaccgacgacatagtcgagcgatta	CRISPR spacer
tggcccctccaccgacgacatagttgagcgattc	Protospacer
************************.********

6. spacer 1.3|46557|34|NC_015163|CRT matches to NC_015163 (Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence) position: , mismatch: 3, identity: 0.912

ggccacgacatagttgagcgattcgggggtaagg	CRISPR spacer
gccgacgacatagttgagcgattcgggggtaggg	Protospacer
* * ***************************.**

7. spacer 1.2|46502|34|NC_015163|CRT matches to NC_015163 (Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence) position: , mismatch: 7, identity: 0.794

cgggggtagggccacgacatagttgagcgattct	CRISPR spacer
tgagcgattggccacgacatagttgagcgattcg	Protospacer
.*.* *   ************************

8. spacer 1.3|46557|34|NC_015163|CRT matches to NC_015163 (Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence) position: , mismatch: 8, identity: 0.765

ggccacgacatagttgagcgattcgggggtaagg	CRISPR spacer
ggccacgacatagttgagcgattctcgacgacat	Protospacer
************************  *.  * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

7362 : 66669

Bacillus_phage(21.05%)

transposase,protease,integrase

attL 34831:34868|attR 65458:65495

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013616000.1\|7362_8265_+\|protease	Protein of unknown function DUF2268, Zn-dependent protease-related protein	NA	NA	NA	NA
WP_169310716.1\|8490_9078_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013616002.1\|9074_9737_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-10	29.5
WP_013616003.1\|9733_10519_+	hypothetical protein	NA	NA	NA	NA
WP_013616004.1\|10695_11241_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_148232021.1\|11257_12130_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_013616006.1\|12126_12414_-\|transposase	transposase	NA	NA	NA	NA
WP_013616007.1\|12598_14785_-	NERD domain-containing protein	NA	NA	NA	NA
WP_013616008.1\|15167_16796_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013616009.1\|17137_18913_+	hypothetical protein	NA	NA	NA	NA
WP_083801597.1\|20857_21106_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013616010.1\|21169_21739_+	hypothetical protein	NA	NA	NA	NA
WP_013616011.1\|23201_24098_+	DNA/RNA non-specific endonuclease	A0A2H4N7Z3	Lake_Baikal_phage	2.1e-23	37.5
WP_013616014.1\|26475_27102_-	recombinase family protein	A0A219YB42	Aeromonas_phage	1.3e-08	31.0
WP_013616015.1\|27212_27683_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_013616016.1\|27863_28628_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	1.4e-07	32.5
WP_013616017.1\|28642_29254_+	pyridoxamine 5'-phosphate oxidase	NA	NA	NA	NA
WP_049775341.1\|29429_29858_+	DUF4158 domain-containing protein	A0A1B0V7H9	Salmonella_phage	6.1e-13	39.4
WP_169310717.1\|29779_32368_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.9e-210	46.5
WP_013616019.1\|33818_34667_+\|transposase	IS5 family transposase	NA	NA	NA	NA
34831:34868	attL	NA	NA	NA	NA
WP_041222302.1\|35002_35986_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_148232029.1\|36113_36953_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_013616021.1\|36985_37273_-\|transposase	transposase	NA	NA	NA	NA
WP_013616022.1\|37718_38258_+	CueP family metal-binding protein	NA	NA	NA	NA
WP_148232023.1\|38458_38944_+	DUF305 domain-containing protein	A0A1E1EVF9	Acanthamoeba_castellanii_mimivirus	5.3e-05	38.7
WP_013616025.1\|39015_39681_+	response regulator transcription factor	W8CYM9	Bacillus_phage	4.3e-42	41.6
WP_013616026.1\|39684_40800_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	1.0e-27	29.1
WP_013616027.1\|41400_41802_-	hypothetical protein	NA	NA	NA	NA
WP_148232024.1\|41994_42177_+	hypothetical protein	NA	NA	NA	NA
WP_013616028.1\|42216_42930_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	6.5e-28	36.5
WP_041223169.1\|44550_45138_-	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	9.2e-20	38.5
WP_013616030.1\|46786_48157_+	replication initiator protein A	NA	NA	NA	NA
WP_013616031.1\|48223_49147_-	ParB/RepB/Spo0J family partition protein	S5VSZ7	Leptospira_phage	5.7e-08	39.5
WP_013616032.1\|49143_49911_-	AAA family ATPase	Q8JL10	Natrialba_phage	2.2e-13	34.4
WP_013616033.1\|50442_51561_-	hypothetical protein	NA	NA	NA	NA
WP_013616034.1\|51758_52985_-	DUF790 family protein	NA	NA	NA	NA
WP_049775355.1\|52971_54345_-	DEAD/DEAH box helicase family protein	A0A1D8BJ75	Sulfolobus_islandicus_filamentous_virus	2.2e-16	24.3
WP_169310718.1\|54383_54623_-	hypothetical protein	NA	NA	NA	NA
WP_169310719.1\|56765_57296_-	hypothetical protein	NA	NA	NA	NA
WP_126352314.1\|58477_59077_+	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	5.7e-17	41.1
WP_013616038.1\|59100_59766_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.9e-38	38.8
WP_013616039.1\|59769_60867_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	7.4e-31	30.5
WP_013616040.1\|60922_63280_+	copper-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.2e-90	36.1
WP_148231767.1\|63309_64010_-\|transposase	IS1 family transposase	A0A077SLN4	Escherichia_phage	6.6e-25	35.3
WP_041223171.1\|65646_66669_+\|transposase	IS4 family transposase	NA	NA	NA	NA
65458:65495	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NC_015170

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_015170_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015170_1

5412-5768

Orphan

Consensus_repeat	Method
CCGACACCTTTGGGCCGTTTT	CRT

5 spacers

The CRISPR arrays of NC_015170_1

>merge|NC_015170|1|5412-5768|CRT
CCGACACCTTTGGGCCGTTTTCGGACCGGAAAAGGTCCAAAGAACGCTGCAAGCAATACCGACACCTTTGGGCCGTTTTTTTGTGGAACTTTCCATACCCAGCCTTTTCTTCGTCCTATACACATTTTTTTGCCCAATGTCCGATACCGACACCTTTGGGCCGTTTGGCGTTTCGATACCGATACCTTTGGGCCGTTTTGATACCGACACCTTTGGGCCGTTTTTGGAGGAATGGGGGTTTATGCCGTGCCGGACAAGGTTTTTCCTACGGAACACCTCAGAGGGCCGTTTTGGCTTCCATTCCCGACACCTTTGGGCCGTTTGACCATTTCTTTCCCGACACCTTTGGGCCGTTTT

>NC_015170|1|1|5412-5768|CRT
CCGACACCTTTGGGCCGTTTT	CGGACCGGAAAAGGTCCAAAGAACGCTGCAAGCAATA
CCGACACCTTTGGGCCGTTTT	TTTGTGGAACTTTCCATACCCAGCCTTTTCTTCGTCCTATACACATTTTTTTGCCCAATGTCCGATA
CCGACACCTTTGGGCCGTTTG	GCGTTTCGATACCGATACCTTTGGGCCGTTTTGATA
CCGACACCTTTGGGCCGTTTT	TGGAGGAATGGGGGTTTATGCCGTGCCGGACAAGGTTTTTCCTACGG
AACACCTCAGAGGGCCGTTTT	GGCTTCCATTCCCGACACCTTTGGGCCGTTTGACCATTTCTTTC
CCGACACCTTTGGGCCGTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_015170.1\|WP_013623141.1\|826_1624_+\|LamB/YcsF-family-protein	unknown	unknown	gnl\|CDD\|377121
NC_015170.1\|WP_041223121.1\|166_742_+\|hypothetical-protein	unknown	unknown	unknown
NC_015170.1\|WP_013623144.1\|4471_5296_-\|CoA-ester-lyase	unknown	unknown	gnl\|CDD\|225184
NC_015170.1\|WP_013623145.1\|5911_7327_+\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|227821
NC_015170.1\|WP_013623154.1\|17782_18748_+\|ring-cleaving-dioxygenase	unknown	unknown	gnl\|CDD\|319935
NC_015170.1\|WP_013623153.1\|16680_17637_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319935
NC_015170.1\|WP_013623149.1\|12474_13542_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NC_015170.1\|WP_013623142.1\|1595_3095_+\|5-oxoprolinase-subunit-PxpB	unknown	unknown	gnl\|CDD\|224895
NC_015170.1\|WP_013623148.1\|11614_12436_+\|ZIP-family-metal-transporter	unknown	unknown	gnl\|CDD\|223505
NC_015170.1\|WP_013623152.1\|16249_16684_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_015170.1\|WP_013623150.1\|13733_14840_+\|DNA-polymerase-IV	unknown	unknown	gnl\|CDD\|176459
NC_015170.1\|WP_049775321.1\|8695_11452_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|226702
NC_015170.1\|WP_041223132.1\|7641_8796_+\|glycerate-kinase	unknown	unknown	gnl\|CDD\|376844
NC_015170.1\|WP_013623143.1\|3192_4401_+\|divalent-metal-cation-transporter	unknown	unknown	gnl\|CDD\|224826
NC_015170.1\|WP_013623151.1\|15037_16108_+\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411

Protein	Function_ID	Function_description	E-value
NC_015170.1\|WP_013623141.1\|826_1624_+\|LamB/YcsF-family-protein	gnl\|CDD\|377121	pfam03746, LamB_YcsF, LamB/YcsF family. This family includes LamB. The lam locus of Aspergillus nidulans consists of two divergently transcribed genes, lamA and lamB, involved in the utilisation of lactams such as 2-pyrrolidinone. Both genes are under the control of the positive regulatory gene amdR and are subject to carbon and nitrogen metabolite repression. The exact molecular function of the proteins in this family is unknown.	1.28562e-119
NC_015170.1\|WP_013623144.1\|4471_5296_-\|CoA-ester-lyase	gnl\|CDD\|225184	COG2301, CitE, Citrate lyase beta subunit [Carbohydrate transport and metabolism].	3.3675e-86
NC_015170.1\|WP_013623145.1\|5911_7327_+\|replication-initiator-protein-A	gnl\|CDD\|227821	COG5534, COG5534, Plasmid replication initiator protein [DNA replication, recombination, and repair].	7.61907e-28
NC_015170.1\|WP_013623154.1\|17782_18748_+\|ring-cleaving-dioxygenase	gnl\|CDD\|319935	cd08347, PcpA_C_like, C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. The C-terminal domain of Sphingobium chlorophenolicum (formerly Sphingomonas chlorophenolica) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. PcpA is a key enzyme in the pentachlorophenol (PCP) degradation pathway, catalyzing the conversion of 2,6-dichloro-p-hydroquinone to 2-chloromaleylacetate. This domain belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases.	4.11816e-63
NC_015170.1\|WP_013623153.1\|16680_17637_+\|VOC-family-protein	gnl\|CDD\|319935	cd08347, PcpA_C_like, C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. The C-terminal domain of Sphingobium chlorophenolicum (formerly Sphingomonas chlorophenolica) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins. PcpA is a key enzyme in the pentachlorophenol (PCP) degradation pathway, catalyzing the conversion of 2,6-dichloro-p-hydroquinone to 2-chloromaleylacetate. This domain belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases.	2.41378e-49
NC_015170.1\|WP_013623149.1\|12474_13542_-\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	5.22881e-52
NC_015170.1\|WP_013623142.1\|1595_3095_+\|5-oxoprolinase-subunit-PxpB	gnl\|CDD\|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.67576e-78
NC_015170.1\|WP_013623148.1\|11614_12436_+\|ZIP-family-metal-transporter	gnl\|CDD\|223505	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism].	1.24846e-53
NC_015170.1\|WP_013623152.1\|16249_16684_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.50105e-17
NC_015170.1\|WP_013623150.1\|13733_14840_+\|DNA-polymerase-IV	gnl\|CDD\|176459	cd03586, PolY_Pol_IV_kappa, DNA Polymerase IV/Kappa. Pol IV, also known as Pol kappa, DinB, and Dpo4, is a translesion synthesis (TLS) polymerase. Translesion synthesis is a process that allows the bypass of a variety of DNA lesions. TLS polymerases lack proofreading activity and have low fidelity and low processivity. They use damaged DNA as templates and insert nucleotides opposite the lesions. Known primarily as Pol IV in prokaryotes and Pol kappa in eukaryotes, this polymerase has a propensity for generating frameshift mutations. The eukaryotic Pol kappa differs from Pol IV and Dpo4 by an N-terminal extension of ~75 residues known as the "N-clasp" region. The structure of Pol kappa shows DNA that is almost totally encircled by Pol kappa, with the N-clasp region augmenting the interactions between DNA and the polymerase. Pol kappa is more resistant than Pol eta and Pol iota to bulky guanine adducts and is efficient at catalyzing the incorporation of dCTP. Bacterial pol IV has a higher error rate than other Y-family polymerases.	2.02632e-164
NC_015170.1\|WP_049775321.1\|8695_11452_-\|PAS-domain-S-box-protein	gnl\|CDD\|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	2.17781e-60
NC_015170.1\|WP_041223132.1\|7641_8796_+\|glycerate-kinase	gnl\|CDD\|376844	pfam02595, Gly_kinase, Glycerate kinase family. This is family of Glycerate kinases.	6.05968e-157
NC_015170.1\|WP_013623143.1\|3192_4401_+\|divalent-metal-cation-transporter	gnl\|CDD\|224826	COG1914, MntH, Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism].	3.01847e-76
NC_015170.1\|WP_013623151.1\|15037_16108_+\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	1.07082e-94

>NC_015170.1|WP_013623144.1|4471_5296_-|CoA-ester-lyase
MTSLTWRSVLYVPADNLRALEKAQTLGADAVLLDLEDAVAPERKRDARGQAAAALAQAWPCPVLLRVNAPGTPWHHEDLELALAARPDGVVLPKVEDPQQLHPLPGEWPLWAMIETPLGVLRAPEIAAHGRAAGLIAGTNDLARALRTRPDPERRPLLHALSSVVLAARAHGKVPLDAVYNNVRDPEGFRRECRQGRDLGFAGKTVIHPLQVEPANQEFGVTDAEAEQARALLAAWEEARAQGRSVATFSGALVEQMHVDEAREVLALYTRSAG
>NC_015170.1|WP_013623143.1|3192_4401_+|divalent-metal-cation-transporter
MTTQRPKEQNWSVLLGAAFLMATSAIGPGFLTQTSVFTEQLLASFGFVILISIIIDLIVQTNIWRIIAVTGRRTQDTANLVMPGLGSLLAALIVIGGLAFNIGNVGGAGLGLNVMTGLDATTGAILSALFAIGIFLFKEAGQAMDRLAQLLGGVMILLTLYVMFTSHPPYAEAALRTVAPIKFDLFAIITLVGGTVGGYITFAGGHRLLDAGIKGVEALPSVNRGATSAILIASLMRILLFLAALGVVSSGAHLDPDNPPASVFQIAAGDVGYRLFGVVMWAAAITSVVGSAYTSVSFIRSLHPAIERHHTWITVAFIVLSTAVLAAIGKPVAILLAVGALNALILPIALGTMLVAAGRRDLVGDYRHPAWMTWTGWLVVLAMAVLSVRTILTTLPQLFGQS
>NC_015170.1|WP_013623142.1|1595_3095_+|5-oxoprolinase-subunit-PxpB
MHAHYWRNTEPERLPALAAALLSSGLPGLLDAVPAYGSLYVEFDERALPLETLTSWLAGWTPSSSADAGRLVDIPVCYDGEDLAAAAEFSGLSTEQVAQRHSEQTYQVRALGFVAGFPFMETTPPELQLPRRAAPRAKVPAHSLAVAGAQTGIYPVEAPGGWNLLGRTLQAAYDPHREPPFLVQPGDRVRFVAQPAGAPLLPPVQPLDLLPEHPQWPALQVGQPGALSLVMDRGRFRAGRFGLVRSGPLDPEAAALANDLLGNRPDAPLLELHLRGPELEALRACSLAVTGLGLTALVNGQPQPPYSAFTVQPGQRVSFRPSGRGRVTYLALQGGLETGTFMGSASTDLKGGLGRPLRRGQLLGSAQPAAPLRCKRQFLPWWVRRMEAAQEPLQLRLLPAAAGEATESALLGQVYRIRDLDRMGARLDGPTVPGGEITSEGSPVGTVQLPPGGQPIILLNDKGTLGGYRRGGRVHPDDLPRLVQSLPGREVRFVADGIF
>NC_015170.1|WP_013623141.1|826_1624_+|LamB/YcsF-family-protein
MHTDLNADAGESFGNWTAGNDAALFPELTSVNLALGFHAGDPLTLRESVALAVQHGLGIGAHPGYPDLQGFGRRAMSLSPDEIYAATIYQIGALQAFLRLAGAPLQHVKAHGALYMRIHEDPQAGAAFCRAVRELVPEAGLVTLAGPAGEALTQQAREQQLTVWREAFPERAYIATGQLAPRSLPGSSIHDPQEAARRAAEMARGRVTSLEGQLLELQVDTLCIHGDNPQATEIARAVRARLAEESVTLRAMGGAPSARALLAEH
>NC_015170.1|WP_041223121.1|166_742_+|hypothetical-protein
MYQPVSLGQLHLLPPDAAVRVLGQLEHLGRVLRSVTGEAELLGPLRPACTQGRVELWGQLVAAAPNQLLVHGLRPLAPQGPVHRRGAGGATVALRAAAGPFEGTVRTLHYGQTLLAQDAEQRVYRLEWCGPGWPAPGGFARAQGPLAGTFHVQGEVLPQDGTRVQGGGRPAGPATLRVLRAWPLGGPRPHL
>NC_015170.1|WP_013623145.1|5911_7327_+|replication-initiator-protein-A
MGHNTIRGLDTIRDTRSLARFGITSIQVRLAQEEALRWESSFSIAGRRYHLQGFADLGRPRGIDTDVITGLEAIFALRGFPEDNTIITSGYELAQSAHMPDNGRTYERIRESLLRYWRTGFLVREGFEQPGGNGRTTYYNETLGFFEKISFWEQGVRTGDMEQTTLSRDKTLRIVLTPEFAESLRSGYIHQLDRALLRQIEQPPARALYRLLSAHRQQDDGTQAEELAVDLSDWREACGIQDTRPSKVLRSLQAAHDELTAQGYLTGVEIAGRGQKTRLTYHFRQQGDPDPALVALLMDADFGLSLPVAQQFAAEYPGRVEKAIQFVEARRRAGNPPVRSPAGLLRRVLEDQERYVLGGAGPDAAELTDTAGSSSGSRGAPATVDPDWEAEQVARSQALLQAPPAEQWRACRASLKLVLGSHFSSEEWKHFGQACLDGQWAAAELLQEATRAAARLEMQEFVAGLQRALRG
>NC_015170.1|WP_041223132.1|7641_8796_+|glycerate-kinase
MRVLVAPDSFKGSLDASAAAAAIAAGVGAAAPDAEICCLPMADGGEGTLDALTAAGGFGRRTMTVTDPLGRPLTGHYAVRANSAVVELAVASGLTLLHDAELDPRRASTRGTGELLRAAAAELPLGGQVLLCLGGSAANDAGTGLLRALGVRFLDAHGDPLPEGGAALARLESIDLSGLPDWVRGLNIEVACDVTHPLVGPQGASVVFGPQKGAAPPVVAELDRALTRFADVVQRQLGVALHHLPGAGAAGGTAGGLHAVLGARLRPGAALVAAASGLTRRLGQERWDLVWTGEGCLDPQSAGGKVVSEVAALAGARGFPVVALAGQVDSATLDALPGLTAAFALADRPLSLTESRARTAELLTRQAEQLTRLYAAALRRPPAG
>NC_015170.1|WP_049775321.1|8695_11452_-|PAS-domain-S-box-protein
MTEFQRPGDLLAFALETVCAALQCQAGAAFLGEDSQPAAHWGEADPNGTLATHALKARAHATAQGQPRQEAGWAAFLLPALPLLDGTQALPLGVLVLQRPWDNAAEDTAGEAAQQSFTLPPDLQAFVNMAALALDRLNQQAEAAQWQRQAGRARQLLKFSPVAIAAGSLSGELTQVNDAYLNLLGCTRAEFEAGRVDWAALTPPEYRQADAEAFARAFEEGQSGWYEKEMLSAGGERIPLKVALFRHDDDETLVVGYLRDLREQRALEQAQASITAELNALLQQQGLTLAQLAAQLQRQNGELEARTRVLEGMAQLVQDHSLDTDPYDLIQRAQMFAQELLPHGYAVYYEPEGGLWRLKSQVGCVGNDALQRVLDGGIPFEDTHNLITPWRSGQPYFQDAYNHAADGLQTVTGQLMATATIPVLTHGQPRGIFAFGLNVPQSWTETEKVILESLAAQLGLGLERLEHTRLLVERSRELESTNNALAARTRALEGFAELSRDLTLEHDPLQLIGRAQDLLVSLLPGSLSTYYELDIPAAGGRWQLLSHRGESPDPELLNSLLRGLPYGRTTIIDRPYSTEQPFYQDVYDPATNATVDRRQTGLLRTSGSFPVHTAGTVRGVLVVGRFQSAPWTPANRTLLETVLFSLQLALERAEQTQALQRHAQELENSNAELERFAFIASHDLQEPLRTVAILTERLLGSLQSPSEAQLRYSSYIRENIQRMQSLLQDLRDFTELGRRLQEPREVDLSRKVDYALRSLEPQVQRSGAQVTVGTLPPVQGDPVQVQELLTRLLDNALKFAAEGHPPEIQVSAQQQGGWVQVCVQDHGIGIAPEHFEQIFTVFQRLHGRERYSGNGIGLSVARRIAELHGGRLWVESQPGEGSTFCFTLPAADGVPLRTAGSAAPPDGSAVRPSAPDSR
>NC_015170.1|WP_013623148.1|11614_12436_+|ZIP-family-metal-transporter
MQSLLPLLETLTPPQQALAATIFTWSLTALGASLVLFTRTVSPRLLSAAQGLAAGVMLAASFWSLLSPALEMAETQGMVPWIPAAAGLLLGAAFVGGLDKVLPHLHPGFARDQAEGVPVRWSQGALLLAAMTIHNLPEGMAVGVSFGGAGEGVEGASVGSAVALALGIGFQNLPEGLAVALPLYAAGLSRWRAFMFGQASALVEPLGGYLGALFVVNALPILPYALSFAAGAMIFVVIEELIPESQRSGHTDLATQAALGGFVGMMILDVALG
>NC_015170.1|WP_013623149.1|12474_13542_-|GGDEF-domain-containing-protein
MLPSAPTEQQIRQRFTLLGLLSAAIHLVGFGNTWLPDRAMQQAVCGLGLTISLTVLYLVRRSPMNLGLVRARALALAVIWLLASVVPPGLSHTGGASTDPHLLSLMNLALLGYALLPGRLAGWVSAGAYLVFLVSIFYFHGVHQLPYLSAGITLLLLHYVGSHSYELLNVRQRAQHLAHLAAYDHLTGLLNRYGMEEKLRELWDRVQSHGNGDDATLLLLDIDHFKAINDQHGHDVGDRVLRRVSRALTEACPEGQVGRWGGEEFLVVLPPISPSEAKLLPSRLTACLAATGRAIPGGQPVTLSGGGVQFSEADSLPQLIALADQRLYAAKRLGRDRVEWSSAANPQTPLPETAL
>NC_015170.1|WP_013623150.1|13733_14840_+|DNA-polymerase-IV
MTPAPRKIIHIDMDAFYASVEQRDQPKLRGRPLAVAWGGRRSVVLTASYEARSYGVRSAMPLYRALNCCPQLQVVPPRFGAYREVSAQIREIFQSYTPLVEPLALDEAYLDVTDPQRGPRSATLIAGAIRAEVQARTGLSATAGVSVNKLLAKLASGLHKPDGLTVLLPDQADALLLGLPVGDFHGIGPATARKLQALGIASGADLRAADPHLLTAHFGKAGGHFWRIAHGQDDRPVLPDRPHKSVGSEETYGEDLRTLAAVRLRLPVLARLVQARLERAALAGRTVVLKLKFSDRRSVTRQLTLPAPVWQAADLERAAARLLTPQLLAGRPGVRLAGITVSGLRPAGELPLQPALFGPEGDTWGGAG
>NC_015170.1|WP_013623151.1|15037_16108_+|YeiH-family-putative-sulfate-export-transporter
MSAAPAGPSTPVSSAPPAPAPAALWPGLLLCLAISAVSLWLGRAPQLAHFGLSSLTLSIVLGLVAGNLWPRLASGTRAAGVTFSKGTLLRAGIVLYGFRLTLHQLLGIGWAGLVADVLMLSSTFFLTYLLGTRLFRLDAQTSALMGAGSSICGAAAVLATQPVVRARAEQVTVAVATVVLYGTVGIFLYPQMAAAGLWPFGGAAYGIYIGSSVHEVAQVVAAGQAISPEVADAAVTAKMLRVMLLAPFLLALAAWWSRRTPLAEGEARTPISVPWFAFGFVAVTLLNSALPLPANVTAGLIWLDTALLTAAMAALGLTTQLRTLLQAGIRPLLLGLVVFAWLVMAGGLLQTWVQGW
>NC_015170.1|WP_013623152.1|16249_16684_+|MarR-family-transcriptional-regulator
MSRLSPTEAAAWRGFLGAHSRVWTQLDHEFQQEFGVGLPVYELLLTLEEQDELRMSDLAHKLRYSSGGLTRLADKLEAQGLIQRIRCETDGRGFQVSLTPAGQQRLRRMHVFHLRGVREHFLRHLNEDEQKALGEIWAKIGGQP
>NC_015170.1|WP_013623153.1|16680_17637_+|VOC-family-protein
MKRHFSGLHHVSALSSDIARNHAFYTQVLGLRLVKKSVNQDAPTMYHLFYADSAGSPGSDMTFFDFPRAAREHRGRDSICLTTFRVTGSGALEYWQERLTQHGVQAIRRTVDGRERLDFEDVDGTRLALFDDAGEGPRGVVWEGTDVPAEFQLQGLGFSGVTVGDLPPFQAFLERGLNLREGRGYDDGGTPVHVFEMGEGGPHAELHVAVQPDLPRRMPGAGGVHHLALRVRDEAELLNWQRHLGALGYRNSGEVDRHWFQSVYITAPSGIVIELATDGPGFATDEAPHQLGERLSLPPFLEPQRAEIEAKLRPLNTP
>NC_015170.1|WP_013623154.1|17782_18748_+|ring-cleaving-dioxygenase
MTQLQLNGIHHLTAVSAQIRENKRFYTQDLGLRLVKRSVNQDDVSAYHLFYADGQGNPGTDITFFDWAVGRERRGNHTVTRTGFRVRDEASLRYWQERFQELGVQHGELRELDGRASLDFEDPEGQRLRLVTDGGAGDTPSPWENSLVPAEHQLRGLGPIVMTVPNLRNTDLILQKVLNMRPVREYADPESSEHQVHVYEMGEGGGPDKELHVAVRPDLPPAMPGAGGVHHVAFRVPTEDEYHAWTEHFNHFGLRTSGEVDRYWFRSLYFREPNGVLFELATDGPGFGVDEDMATLGETLILPPFLEGQRAQIAAGLKPID

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Crispr_ID: NC_015170_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015170_2

53434-53766

TypeI-E

Consensus_repeat	Method
GGAACATCCCCGCCCACACGGGGAAAAC	PILER-CR
GGAACATCCCCGCCCACACGGGGAAAAC	CRISPRCasFinder
GGAACATCCCCGCNCACACGGGGAAAAC	CRT

5 spacers

WYL,cas3,cas8e,cse2gr11,cas7

The CRISPR arrays of NC_015170_2

>merge|NC_015170|2|53434-53766|PILER-CR,CRISPRCasFinder,CRT
GGAACATCCCCGCCCACACGGGGAAAACCCAACGCCGAAAACGCCGCCGAGTTTAGCGCCCGGAACATCCCCGCCCACACGGGGAAAACCGGCACCCAGCGCGGCCCGGTGGCCCTGGAGTAGGAACATCCCCGCCCACACGGGGAAAACTACGCGGCGGCGTTTAAGGGGCGGAAGCAGGTCGGAACATCCCCGCCCACACGGGGAAAACTGCCGAATCAGAATCCTGAGAGGGTGACGAGGCGGAACATCCCCGCACACACGGGGAAAACTTCCCCAAGACTGATGCCGTGGCTGAAGGTTACGGAACATCCCCGCACACACGGGGAAAAC

>NC_015170|2|1|53434-53766|PILER-CR
GGAACATCCCCGCCCACACGGGGAAAAC	CCAACGCCGAAAACGCCGCCGAGTTTAGCGCCC
GGAACATCCCCGCCCACACGGGGAAAAC	CGGCACCCAGCGCGGCCCGGTGGCCCTGGAGTA
GGAACATCCCCGCCCACACGGGGAAAAC	TACGCGGCGGCGTTTAAGGGGCGGAAGCAGGTC
GGAACATCCCCGCCCACACGGGGAAAAC	TGCCGAATCAGAATCCTGAGAGGGTGACGAGGC
GGAACATCCCCGCACACACGGGGAAAAC	TTCCCCAAGACTGATGCCGTGGCTGAAGGTTAC
GGAACATCCCCGCACACACGGGGAAAAC

>NC_015170|2|1|53434-53766|CRISPRCasFinder
GGAACATCCCCGCCCACACGGGGAAAAC	CCAACGCCGAAAACGCCGCCGAGTTTAGCGCCC
GGAACATCCCCGCCCACACGGGGAAAAC	CGGCACCCAGCGCGGCCCGGTGGCCCTGGAGTA
GGAACATCCCCGCCCACACGGGGAAAAC	TACGCGGCGGCGTTTAAGGGGCGGAAGCAGGTC
GGAACATCCCCGCCCACACGGGGAAAAC	TGCCGAATCAGAATCCTGAGAGGGTGACGAGGC
GGAACATCCCCGCACACACGGGGAAAAC	TTCCCCAAGACTGATGCCGTGGCTGAAGGTTAC
GGAACATCCCCGCACACACGGGGAAAAC

>NC_015170|2|2|53434-53766|CRT
GGAACATCCCCGCCCACACGGGGAAAAC	CCAACGCCGAAAACGCCGCCGAGTTTAGCGCCC
GGAACATCCCCGCCCACACGGGGAAAAC	CGGCACCCAGCGCGGCCCGGTGGCCCTGGAGTA
GGAACATCCCCGCCCACACGGGGAAAAC	TACGCGGCGGCGTTTAAGGGGCGGAAGCAGGTC
GGAACATCCCCGCCCACACGGGGAAAAC	TGCCGAATCAGAATCCTGAGAGGGTGACGAGGC
GGAACATCCCCGCACACACGGGGAAAAC	TTCCCCAAGACTGATGCCGTGGCTGAAGGTTAC
GGAACATCCCCGCACACACGGGGAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015170.1\|WP_013623180.1\|54093_54240_+\|hypothetical-protein	unknown	unknown	unknown
NC_015170.1\|WP_013623178.1\|51164_52313_-\|phosphoserine-transaminase	unknown	unknown	gnl\|CDD\|235103
NC_015170.1\|WP_013623172.1\|41923_44287_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NC_015170.1\|WP_013623181.1\|54289_55990_+\|tetratricopeptide-TPR_2	unknown	unknown	gnl\|CDD\|380042
NC_015170.1\|WP_013623187.1\|64380_65166_-\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|372648
NC_015170.1\|WP_148232009.1\|62776_63055_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	unknown	unknown	gnl\|CDD\|187860
NC_015170.1\|WP_148232016.1\|63089_63734_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	pfam09485_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NC_015170.1\|WP_013623173.1\|44431_45658_-\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|223740
NC_015170.1\|WP_148232015.1\|60135_61668_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|187860
NC_015170.1\|WP_013623179.1\|52439_53318_+\|phosphoserine-phosphatase-SerB	unknown	unknown	gnl\|CDD\|319803
NC_015170.1\|WP_013623182.1\|56068_57088_+\|WYL-domain-containing-transcriptional-regulator	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_015170.1\|WP_013623176.1\|47958_49269_-\|Nramp-family-divalent-metal-transporter	unknown	unknown	gnl\|CDD\|234815
NC_015170.1\|WP_013623175.1\|46046_47753_-\|DUF839-domain-containing-protein	unknown	unknown	gnl\|CDD\|225752
NC_015170.1\|WP_013623174.1\|45750_46044_-\|hypothetical-protein	unknown	unknown	unknown
NC_015170.1\|WP_148232007.1\|39409_40633_+\|phosphoesterase	unknown	unknown	unknown
NC_015170.1\|WP_013613827.1\|61607_62681_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_015170.1\|WP_013623171.1\|40737_41883_+\|HupE/UreJ-family-protein	unknown	unknown	gnl\|CDD\|379373
NC_015170.1\|WP_013623177.1\|49506_51111_-\|phosphoglycerate-dehydrogenase	unknown	unknown	gnl\|CDD\|237436
NC_015170.1\|WP_013623183.1\|57069_59961_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NC_015170.1\|WP_049775327.1\|63730_64363_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153

Protein	Function_ID	Function_description	E-value
NC_015170.1\|WP_013623178.1\|51164_52313_-\|phosphoserine-transaminase	gnl\|CDD\|235103	PRK03080, PRK03080, phosphoserine transaminase.	0
NC_015170.1\|WP_013623172.1\|41923_44287_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.24767e-100
NC_015170.1\|WP_013623187.1\|64380_65166_-\|IS982-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.6258e-13
NC_015170.1\|WP_148232009.1\|62776_63055_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	2.54804e-05
NC_015170.1\|WP_013623173.1\|44431_45658_-\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	2.48868e-46
NC_015170.1\|WP_148232016.1\|63089_63734_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	1.04452e-25
NC_015170.1\|WP_013623179.1\|52439_53318_+\|phosphoserine-phosphatase-SerB	gnl\|CDD\|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.83732e-83
NC_015170.1\|WP_013623182.1\|56068_57088_+\|WYL-domain-containing-transcriptional-regulator	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	1.22786e-32
NC_015170.1\|WP_013623176.1\|47958_49269_-\|Nramp-family-divalent-metal-transporter	gnl\|CDD\|234815	PRK00701, PRK00701, divalent metal cation transporter MntH.	0
NC_015170.1\|WP_013623175.1\|46046_47753_-\|DUF839-domain-containing-protein	gnl\|CDD\|225752	COG3211, PhoX, Predicted phosphatase [General function prediction only].	3.15627e-137
NC_015170.1\|WP_013623183.1\|57069_59961_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	7.85271e-97
NC_015170.1\|WP_013623181.1\|54289_55990_+\|tetratricopeptide-TPR_2	gnl\|CDD\|380042	pfam17874, TPR_MalT, MalT-like TPR region. This entry contains a series of TPR repeats.	3.26326e-06
NC_015170.1\|WP_013613827.1\|61607_62681_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.18879e-08
NC_015170.1\|WP_013623171.1\|40737_41883_+\|HupE/UreJ-family-protein	gnl\|CDD\|379373	pfam13795, HupE_UreJ_2, HupE / UreJ protein. These proteins contain many conserved histidines that may be involved in nickel binding.	8.18999e-56
NC_015170.1\|WP_013623177.1\|49506_51111_-\|phosphoglycerate-dehydrogenase	gnl\|CDD\|237436	PRK13581, PRK13581, D-3-phosphoglycerate dehydrogenase; Provisional.	0
NC_015170.1\|WP_148232015.1\|60135_61668_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	1.09644e-76
NC_015170.1\|WP_049775327.1\|63730_64363_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	8.2977e-33

>NC_015170.1|WP_013623179.1|52439_53318_+|phosphoserine-phosphatase-SerB
MYTATLLTAPDRPSLTAGGVEALLARWQGHGLRWLAPGEAAEFELPHLPDDRWTVWAELQAQGTDLAVQRSGSRRKRVLLADMDSTMIAQECVDELAAAAGVGPQVAEITARAMNGELDFGAALLARVALLRGLPQEVAAQVLAGRITLTPGGRELVATMRAHGGYAALVSGGFTVFTGAVAAQLGFDEHRANTLLVDGGRLTGDVSRPILGRQAKVDALLDITARLGLQPQDVLAVGDGANDLGMLELAGTGVALHAKPAVAAQCGVRIHHGDLTALLYLQGYARDEFVSP
>NC_015170.1|WP_013623178.1|51164_52313_-|phosphoserine-transaminase
MEDLVRPAVRPTNPNFSSGPCAKFPGFQLDLLQGAPLGRSHRAAPGKARLAEAIELTREVLEVPHDYRIGIVPASDTGAVEMALWSLLGARGVEVLAWESFGEGWAADVVEQLGLDAAVRRAPYGEIVDFSQVDFGSDVVFTWNGTTSGVWVPDGDLIPADREGLTICDATSAAFAVELPWDRLDVVTFSWQKALGGEGGHGMLVLSPRAVERLESYTPPRPLPKIFRLTQRGRLIEGIFRGETINTPSMLCVEDYLAALRWAQSVGGLPALVARSQANAQAVADWAAGRDWVTNLAADPATASTTSVCLRFTDPRIRDADAFAAAVARRLDREGAGHDLGSYRDAPAGLRIWCGSTVETADVQALLPWIDYAFHAELAAQA
>NC_015170.1|WP_013623177.1|49506_51111_-|phosphoglycerate-dehydrogenase
MPPKVLVSDALSETAVQIFRDRGVDVDYRPEMGKDPAALAAIIGDYDGLAIRSATRVTPELLEKAGRLKVIGRAGIGVDNVDISAASRRGIIVMNTPFGNSVTTAEHAIALMFAVARQLPEASASTHAGRWEKNRFMGVELTAKTLGLIGAGNIGSIVADRAQGLHMKVMAYDPFLSQERALELGVRKVELDELLEHADFITLHVPLTDKTRNLLSRENLLRTKPGVRIINAARGGLLDEEALAELLRSGHVAGAALDVFAQEPATQSPLFGLPNVVVTPHLGAATTEAQENVALQVAEQMSDYLLSGAVHNALNMPAVTAEEAARMGPWIHLARHLGAFVGQMVEEPMTSLNITYGGAAAGMNTGALNAALISGLMKPSNPDANMVSAPLMAREKGIQVATTIQDQSGGQQAGNFGGFIRLDVTTESGERSVAGTVFSDGKPRFIQIRGINLDAEVGEHMLYTRNRDVPGVIGSLGTALGDLGVNIANFTLGRSAQGDAIAIIYLDEPLPAAAAQALRDSGKFIQVRPLHFEL
>NC_015170.1|WP_013623176.1|47958_49269_-|Nramp-family-divalent-metal-transporter
MSVSAEPSTSAGLSLSSAQPPDAQASAVLAGQSQKRGLARILPFIGPAVIASIAYMDPGNFATNIQGGADFGYRLLWVILAANLMAMLIQSLSARLGIATGKNLPELIRERWPRPLVWFYWVQAELVAIATDLAEFIGAAVAIHLLTGLPLLWGAAVTAVISLWILGFQSRGRRPAELLIGGFVLVIGLAYLVQFVMARPQLASLGQGLVPSFAGPDSVYLAVGIIGATVMPHVIYLHSALTQGRVQATTDEQKLRLARLNRIDVMGAMGLAGVINMAMLAVAAATFHGQNIPDAGNLETAYRTLTPLLGPAASVAFAVALLASGLSSTVVGTMAGQVIMQGFVNFSIPLWVRRTVTMLPAFVVILLGLDPTRTLVLSQVILSFGVPFALVPLLLFTARRDVMGVLVSRPAVTRLGWVIATLIIGLNGYLLWETLR
>NC_015170.1|WP_013623175.1|46046_47753_-|DUF839-domain-containing-protein
MSHSPEQTPEKRSFWHQLLDTRISRRSAITTAAATAAAASLPVSFAQAQQSGVTTANNGAPIGVTPRENARTYPPFRPIEPTRADDLTLPPGFRYQILAPWGEEFTQDGRTIGFNHDFIGYFPADMLEGGHSSTDAYLTINHEYVNSLFLGTEERTPANIEKEKRAMGVSVVRVRQQGGEWKVVKDAKNRAVDGLYDIELTGPVRGTDAVKGATMVKGTVGNCSGGQTPWGTLLTCEENVDGYVKAWEGSGYEAMHQGWVTEIDPFDPAWTPKKRTGMGRFRHENVAPGRTADGRFVGYMGDDMQDSCVYKFVSRQPISGDRAADRNLLEDGDLYVANFGNGTWVLLDYDKNKKLQDAKKDDKPLFSSQAEVLADARAAALAVGGTPVDRPEDIEIHPLNGDVYIALTNNSKHGNYFGHIVRLTEEGSDHAATSFKWDVFAYGGPSAGFASPDNLVFDPYGNLWMVTDNSDLGTNPIKDFHGNNAMFFMPTEGPNAGKAYRFAVGPVEAEMTGPTWSPDGKTLFVSIQHPGEDSESLDKLTSNFAAKPGSRIPRPTLVAIQGFPGWKA
>NC_015170.1|WP_013623174.1|45750_46044_-|hypothetical-protein
MTLPTYRAGHIVQGEPLMIHALEDFVGELTRQRPWVKARYEEALEAVDDLLSQDTPAGLAAYLAADRAELLAALPEQPLLTEALDEFGAYLREWRWV
>NC_015170.1|WP_013623173.1|44431_45658_-|mechanosensitive-ion-channel-family-protein
MWEELQLQIIKPAAWFKFGLGLLVTVALYRLGLTVLRLLRPRMSQGFYPVLHGLLLLSSLLLLLGLSTQAFYLTSSPLFDLGKSVMDALQATGGQLLLIAALSLVAWSLIGEAAGRIVPSDEFNRRTVRVRTLKGVVESTLKAVVLFTALIAVLQTVGVNATSLLASASVLGLAVSFGAQSLIKDIFNGFFILLSDQYGVGDDVDLNLGAVSGTVEAIDLRTTSVRDISGTLHIMQNGQITAISVKSKDWARVVATVDVAYEADVDQAIRVLEQVSRDLYADEHWHSYFLSEPDVQGVTALGTDAITLRALFKVGPKSQYAVGREFNRRIKIAMDEAGISIPYPQRRMSFGDGPLEIRLVQGNAVQANPAQGDPAQVELAQGTPFPHAPAEQDRQSPLVTPPLKRNAD
>NC_015170.1|WP_013623172.1|41923_44287_-|EAL-domain-containing-protein
MDEQIQRLELQILNRPQQTELELTALLTQARQQADIQAEAHALCLMAEGAFFQGNYPAALEWAGHGQALAQQHRLTALEARNHNALSMACWRLGRLPEALDHVRASLALAGDDALARSRALSSAAAIYIELGDHERALENFGQAAELARHSEQPEQAATPMTGTVRAMLHMGRMEALELVPEVRALAEQHGMLWLLCVLSYLEASLLHRLGRPEEGRACAEAGLAQAQQTGNAEAQGFLHQILAELYLASGALEWASAQLEQGGQIARQLNHLQLHCGLESSRAKLHQLNGDHAAALGALHRHIELSQQLHARSHQLHSRTVSQQIEVELLQRAAQHGQCSSELLQANRELQTLQERLSYQASHDSLTGLLNRSAFWTRTQERLRQRLRAACSGVIMAHISHLRSINGARGHAAGDILLQEIAQRFRAELRPGDLVGRLSGDEFMIYLDNLSCPEQLEQEAQRLLRSLVEPLVSGHLVIRPAISLGCAVAPPDGHDLGHLHQCADLALQQAKQQGNNGWVRFQPETGAAELRRQQLREDLRHALERGECELHYQPQFSLPERRLVGVEALLRWRHPQLGTISPAEFIPLAEEGPLILELGAWALREACCQAQTWNFGERKLLMSVNVSVRQFERPDFVPQVEAALAACGLPGGCLILELTETLLHQEAQVGAQTFNELHRLGVHIAIDDFGTGYSNIQLLRHLPFRQLKIDRSFVQDLADGAAGLASAQHFMKVMLNLAHGLGINVVAEGVETQAQFDLLTQLGCDKAQGFLLSPPLPAGELASTFL
>NC_015170.1|WP_013623171.1|40737_41883_+|HupE/UreJ-family-protein
MPTAVRAALTLLACCALSGRAGAHATSDHFLNLQVDGSSVNGHWDVMLNDLDYVLHLDADQDGRVSNDELAQSGQQARDYLLGHLTVTADGASGGGQPCSLTDSGMQVGRQDNGRFLRLSLTGECAVAPQTLQVSNTLFTDTGDQDTHRGYLNLEYAGQTQTSVFGPGSTAANVSLQAPSKLESLVKFIWLGMTHIWGGLDHVLFLITLLLPSVLRYREGRWQPVGSFREALISVVKVVTAFTVAHSVTLSLAALDVIHLPSRLVEAVIALSVVLAALNNVYPLVRERFLWAVAFAFGLVHGFGFSSVLGELVSDRRALVESLLGFNIGVEIGQLALVAVTVPLIFWLRHTVFYRRLVFAPLSALIAVIGAVWFMERAFAA
>NC_015170.1|WP_148232007.1|39409_40633_+|phosphoesterase
MAVKHGLSWMVITDHGGPNHSKLNMERAYPELLQARKQFPQLLSFVGMEFNMPAMDHHTLMIPHTDRESQTLFDIENKWDKAEAYPTDKSRDTEEKALQTINYVKNMQGPKPIFMANHPARSAKGLGVYGADTPHELRNNNDAAPDIYVGFEGAPGHQAGGLNRDGSLDPKGSRGSYGSHPTYGGFDQMTARVGGLWDSMLGEGRRFWIVATSDSHVHYTDGGSDFWPGEYQKIYVKADKSYDDVLDGLRNGRTFVTSGDLISELDMSVAAGGKRVSLGETLKLGGAQDVTVTVKLRDPAGNNFHGENPAVSRVDLIVGDVTGKVASSQYDNDTNPSTKVEKRFKADSWKRDGEYITMTYTLKNVNKNMYLRLRGTNTDQLEPEADPKGENPWNDLWFYSNPVFIEF
>NC_015170.1|WP_013623180.1|54093_54240_+|hypothetical-protein
MLKHFFSLCLIAFFAASPLAAAAPLQPAGGDVVLAMSDDPTIGGRGLG
>NC_015170.1|WP_013623181.1|54289_55990_+|tetratricopeptide-TPR_2
MGGIAVTDGEWQASIQALLELGRVDEALDTVYRATGETRAPAQFAQLLKLLEQFPAAAQAKPQWVRGQLRLLGNLGRLEDLGKQTAHWLAAGAGKDWTFLSVFMAWQAAEQGDDALSLKYGQAAYAAQQADLTPFERALLLRVLGRVKFRQGQAGWEDHFEQALAEGTGRARVLTLLEYGAILSHTTQTATTIRILSEAQALAAQARDDQLRMNASELLGRAYLRAGEFTEADKHLSTLEKLARRKDNRHLLSYALHCLAIPRRTLGEWVQAEALYSEALKCAGEMGNEFEQRQALRGLGHTRRLSGRALGALEVLEQAARVVKEDRDTGKSVVNVDIAAALVSLPHLDSAAVLDRLGKAGRLSEEGLQRAELVRAELDRRQGNAAAALERLAALDRGQLWLREEAHAFPELFALLPAGERPLPLPRPQRPLVRLEAMGFPKVLVNGRMVSSSALAVVVLAALLHEGPQLSTDRLTEVLDDGKPRTRRQAEQRLSKTVGTLRAALGWAGSIETGPGFYALDSGTDWQFDVAEALSSGAAIPAFLPGLDFPWVTDTEQRLSLGDLDI
>NC_015170.1|WP_013623182.1|56068_57088_+|WYL-domain-containing-transcriptional-regulator
MDSVDLQGSRPQPQKKRPVREAKTWDRVKRLIQMSKDLQAAPMTTAMMARAYGTSQRTIQRDIEVLRELGHDIPLPDRLHRYVILQRGGALLPAQALAAYAAVRLAYHHSPSHNRHYRDAMLHISAQLPERIRYVLGGSVLDNGAGQMTERELEKVATAWVEGRVLSFDYQRPGGELDRGNRLCVYFLEISRSNLAPYVIGLEQRRGQLRTFKLSRMRTMEVLRDTYEPDESFDPREFLSDAWGVVGSQNPITVQVRFASEAAYRLDEGGYPNATFHKQPDGSVLAEFRAGTDKTGLPRELMPFLLGWGPRAEVLGPPEVRAHWLSELRETLRRYDNFS
>NC_015170.1|WP_013623183.1|57069_59961_-|CRISPR-associated-helicase/endonuclease-Cas3
MTTLAPLTRITASLWAKSPKPTGEVKLGVLEHLLNVAACAAEILELEPPHVKAQMAADLGLELEQGLNWVLALVALHDLGKASPAFQMKWAEGMKAVDGWLSVSRLLREPYTFHGVVSEFCLPDFLVGQLQWSSRLAEHVSDAVGCHHGFRVENLALQDVSPAQIGDDRWRKVRFELCRLVTVAVGADYSVVPPVKEFSAAAFMRLAGLTSFADWLGSSFPLPTQTDFSAYEDPAAYFAEARAQAKKLLTDPKTGIHWPQFAPLHPALPHLEDVFSYLANGEFRPRPLQTALAEALAQVDGSTLVLAEAPMGEGKTEAALYAYLQLQHAAQHRGLYVALPTQATGSAMFERLVEFLRAQGSQRPVSIQLAHGGTLLNDEYQERVENTRLFYRTNTDAEGEQSVEAVRAEEWFTSRKRALLDEFGVGTVDQALLGVLGVSHQFVRLWGLGNRVVVLDEVHAYDTYTSELIAALVAWLRALGSSVVIMSATLPDESRRKLLGAWGAREIPAAVNYPRWTVATQTGEVTAGTIPDTDAEGNRSRPTQQIALHSLPASAEAVAAQAVELTLNGGCTAIIVNTVQRAQAVQSEVLRLLAERGVAAQTCTGAVAKGAEWVGVLLYHARYPADERQYRERAVLKYLGKEGQRPERFILIATQVAEQSLDFDADVMISDLAPLDLLLQRAGRLHRHQRPPASRHVHVHPALYIAGLGEWPAAALKAEAWGRVYAPALLYRTWRILQGRQTLTLPTELDDLVQQVYGAALATADLTDEQAQTIQAAEEKLLAERAGQASKGRFAHIGLPTEFWQTRLTHVLEEPDTESVNDDALADEDEFPRTRLGDESVRIVPVQQANGKWVVCPPPKAMQPKNEPWQEVVTHHQTLDKGDMHTAKRIFRRSLSISRWEVVRAAKEGRLWTHGLGGDKRGWAAHPLLRDAVPLDLTAGYKDLGRLRLRLDPELGLVYEKLS
>NC_015170.1|WP_148232015.1|60135_61668_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MVSFSLLRENWVPVLDLEGKTASVSLSDTLLTPQLYRRIDAGHPLHTAALYRLHLALLHRALGPSSAEDAAQWYSAGFPSEKVQAYLECYADRFDLFGPQPFMQVVGLDPASVGENFRSHWTRLSTEDGSPNTTALFNVEARPNGGRMDEITAAEAAVQLLSQQSFTLGGLIKRFTTSARAAPVATAALFLAEGHNLQQMLALNLVPYTASMAARDLPVWEQPPLTVADIQRIYADKEPKPRPAEGFVSRYAWPSRSILLLPEQTEGGLKVRTIGFGAGVPLAGAGEGAGANLDPMVGLLPSRDDKGDPYPYKLRRDRLLWRDLTALLPSPEVKVSEAKDGKGKKKVTAKPGRTAYVLEHAAEVMRLVQAQRQPAAPPVRPVVSQSQAAELDEPLPDAPAAPPVLPVVVFGQLTDQGKAFAIRQETYTLPQRFIENPEHFHDYIKGSLETATMVGNALWSAVKHLAEELLKKDGSRSPDPADIRKLSEQTDYPSKRGTSRARRFQFSGLG
>NC_015170.1|WP_013613827.1|61607_62681_-|IS4-family-transposase
MNHLNQPPQDSLFTALRPFFRIDQRRFTVLVALILAIIQQRSVVLNNLKATITLPGSREMRYQRLLRFVQFLIPEEMYLKFALHVLGTDELTLILDRTNWKLGKRDVNILMLSAVWEGFSLPLMWRFLPHGGSSDQRIRKELMADFLRHCPQVHIDGLLADREFIGQDWFTFLSEHGIAPCIRLRSDTKMDSLPVHVFAKKMQVGEVRVWHSSMVVYGVRLRVLALKVSKTEMLYLAYKGRADQNLRKYALRWQCENLHAALKTRGFDLEATGLTQAERVSTLLMVIAISFIWCLRTGTVLLLEGNVETMKAKRQKAHGYASKSLFRLGLDELRDLLSHPSPENWNRLARLVPRFEG
>NC_015170.1|WP_148232009.1|62776_63055_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MPAVTTFWQRLEAPFRQYLLNLDGDPEQATLEWNAALKQAAWQGWNIAQEAAGMNAVGLRAVQKSQGLLLKVLGGLPVPVQPVPATTENTDD
>NC_015170.1|WP_148232016.1|63089_63734_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MRELVRLERGKLAQLRRGLGGDNRSVYWLEGLYARTGYAEATPTGKEALRLVAGLYALKPKALDDGDEPEQSAETAPEAPRKAVSIGKQMGQLYLQQDRRPSTEKRFLALLDTDREGIGYHMRQVVTLLDTADLTPDWERLVTDLLYWSDRTRKGWAQDFYAEIFREENRQDDKTGGTLPSSDTSVGSPASAPLFASSQPDHQPADQDDEGETL
>NC_015170.1|WP_049775327.1|63730_64363_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MKAVLELHYLQNFAPSNLNRDDIGSPKDAFFGGTRRLRISSQSFKRAMRQDFAQRQILSEAELGLRSKRLLFSEDPREKGLVNRLVQGENALKTEEARFRAEFALLMNGIAFVEVKGEEDNYILDDTKSEALAFLGEYNLALLEKFLKSDSDEVQKASAVMREAREKLRKSKGYKGKIGESSAKEKLRKAISTALGSKKKELDEILNNRE
>NC_015170.1|WP_013623187.1|64380_65166_-|IS982-family-transposase
MGRPDLTLLPIHEALQVLSQWVKPHIPAKLLHKHEKISDADLIGIAILQMLHKQPYFSRWWHFLTVNHFPDLPSETQARIRLKRLLPVIEHLSHEVQALDFVAVDSEPLPVCTFKRAPRCKFRGARHGFSTAGPVFGFKLHAWCGLNGEIVAYNIRAANEHDYSVLCEMNRKWPAYGGPQQIGDKGYQSLTTITPPKVNARRPSPRWREEFGAARKCIESAFSVLVGAGLRWGQVKTMASLKLKVALHVLAHNLKYRDLIT

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Crispr_ID: NC_015170_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015170_3

68585-68675

TypeI-E

Consensus_repeat	Method
GTTTTCCCCGTGTGTGCGGGGATGTTCCGG	CRISPRCasFinder

1 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e

The CRISPR arrays of NC_015170_3

>merge|NC_015170|3|68585-68675|CRISPRCasFinder
GTTTTCCCCGTGTGTGCGGGGATGTTCCGGACATCCAGGCCCGGCGCTTCATTGTTCGTGGGTTTTCCCCGTGTGTGCGGGGATGTTCCGG

>NC_015170|3|2|68585-68675|CRISPRCasFinder
GTTTTCCCCGTGTGTGCGGGGATGTTCCGG	ACATCCAGGCCCGGCGCTTCATTGTTCGTGG
GTTTTCCCCGTGTGTGCGGGGATGTTCCGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_015170.1\|WP_013623196.1\|74472_75636_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340840
NC_015170.1\|WP_013623194.1\|71612_72884_-\|LCP-family-protein	unknown	unknown	gnl\|CDD\|181811
NC_015170.1\|WP_148232011.1\|70265_71477_-\|hypothetical-protein	unknown	unknown	unknown
NC_015170.1\|WP_013623187.1\|64380_65166_-\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|372648
NC_015170.1\|WP_169310714.1\|73218_74472_+\|oligosaccharide-flippase-family-protein	unknown	unknown	gnl\|CDD\|225153
NC_015170.1\|WP_049775327.1\|63730_64363_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NC_015170.1\|WP_148232010.1\|68173_68518_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09707_cas2_CAS-I-E	gnl\|CDD\|378244
NC_015170.1\|WP_148232016.1\|63089_63734_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	pfam09485_cse2gr11_CAS-I-E	gnl\|CDD\|378191
NC_015170.1\|WP_169310715.1\|79307_79463_+\|hypothetical-protein	unknown	unknown	unknown
NC_015170.1\|WP_013613827.1\|61607_62681_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_015170.1\|WP_148232015.1\|60135_61668_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|187860
NC_015170.1\|WP_148232009.1\|62776_63055_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	unknown	unknown	gnl\|CDD\|187860
NC_015170.1\|WP_013623199.1\|78193_79321_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340837
NC_015170.1\|WP_013623188.1\|65874_66579_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09756_cas5_CAS-I-E	gnl\|CDD\|187886
NC_015170.1\|WP_013623189.1\|66578_67226_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|378050
NC_015170.1\|WP_013623190.1\|67229_68177_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NC_015170.1\|WP_013623198.1\|77009_78197_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|379337
NC_015170.1\|WP_013623192.1\|68723_69962_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235540
NC_015170.1\|WP_013623200.1\|79571_80597_-\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|187558
NC_015170.1\|WP_041223126.1\|75632_77006_+\|O-antigen-ligase-family-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_015170.1\|WP_013623196.1\|74472_75636_+\|glycosyltransferase	gnl\|CDD\|340840	cd03812, GT4_CapH-like, capsular polysaccharide biosynthesis glycosyltransferase CapH and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. capH in Staphylococcus aureus has been shown to be required for the biosynthesis of the type 1 capsular polysaccharide (CP1).	1.36858e-82
NC_015170.1\|WP_013623194.1\|71612_72884_-\|LCP-family-protein	gnl\|CDD\|181811	PRK09379, PRK09379, LytR family transcriptional regulator.	1.60151e-62
NC_015170.1\|WP_013623187.1\|64380_65166_-\|IS982-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.6258e-13
NC_015170.1\|WP_169310714.1\|73218_74472_+\|oligosaccharide-flippase-family-protein	gnl\|CDD\|225153	COG2244, RfbX, Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only].	3.58259e-22
NC_015170.1\|WP_049775327.1\|63730_64363_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	8.2977e-33
NC_015170.1\|WP_148232010.1\|68173_68518_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378244	pfam09707, Cas_Cas2CT1978, CRISPR-associated protein (Cas_Cas2CT1978). This entry represents a minor branch of the Cas2 family of CRISPR-associated protein which are found in IPR003799. Cas proteins are found adjacent to a characteristic short, palindromic repeat cluster termed CRISPR, a probable mobile DNA element.	3.06264e-35
NC_015170.1\|WP_148232016.1\|63089_63734_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|378191	pfam09485, CRISPR_Cse2, CRISPR-associated protein Cse2 (CRISPR_cse2). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family of proteins, represented by CT1973 from Chlorobaculum tepidum, is encoded by genes found in the CRISPR/Cas subtype Ecoli regions of many bacteria (most of which are mesophiles), and not in Archaea. It is designated Cse2.	1.04452e-25
NC_015170.1\|WP_013613827.1\|61607_62681_-\|IS4-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	3.18879e-08
NC_015170.1\|WP_148232015.1\|60135_61668_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	1.09644e-76
NC_015170.1\|WP_148232009.1\|62776_63055_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	2.54804e-05
NC_015170.1\|WP_013623199.1\|78193_79321_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340837	cd03808, GT4_CapM-like, capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.	4.30203e-77
NC_015170.1\|WP_013623188.1\|65874_66579_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|187886	cd09756, Cas5_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	1.18423e-45
NC_015170.1\|WP_013623189.1\|66578_67226_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|378050	pfam08798, CRISPR_assoc, CRISPR associated protein. This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	7.99509e-59
NC_015170.1\|WP_013623190.1\|67229_68177_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	1.09658e-137
NC_015170.1\|WP_013623198.1\|77009_78197_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|379337	pfam13692, Glyco_trans_1_4, Glycosyl transferases group 1.	9.02105e-33
NC_015170.1\|WP_013623192.1\|68723_69962_-\|hypothetical-protein	gnl\|CDD\|235540	PRK05641, PRK05641, putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated.	4.38041e-05
NC_015170.1\|WP_013623200.1\|79571_80597_-\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|187558	cd05247, UDP_G4E_1_SDR_e, UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	6.50073e-128

>NC_015170.1|WP_148232010.1|68173_68518_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MSHDCDDAGKVPEALHGELSRWLIEVQTGVYVGSVSAVVRDLLWDKVVQHSRSGRCTQLFRSNNEQGFVIRMHGEARRTLVDVEGYQLVAVKNARYEQLLPKFTPEEEDDWETL
>NC_015170.1|WP_013623190.1|67229_68177_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MTGATVQDSGPIIWKRQNLRELPKFRDGTSYLYLEHTVLEQSGRSIQAFHPEGMVEIPCASLGVLLLGPGTSVSHSAMTALSRTGCSVVWVGEQGVRFYAAGIGEASKSGRLMRQARLWANEKSRMRIIRQMYTMRFPEGLPDDLTLQQIRGREGARVRALYSSYSKAHGVKWQERKYNRANWDDASPINKAISAGNTCLNGLAHAAILSLGYTPALGFVHTGKQLSLVYDITDLYKMEVVSPIAFQEAAKGGEDIDRRVRLALRDHIRQARLLERMANDLLTLFEDEYEDDPQEEDVGELYDPDGDVAGGKNYG
>NC_015170.1|WP_013623189.1|66578_67226_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MYLSRLFLNDHSKQAAADLRSAYGLHQTLRWAFPNAGEENGPLPEGERLLWRDDGPHGILVQSVTRPSWDAVSARHPDYFHDVQVKPFDLTGLQAGQHLAFKLKANVTVNRWRDGQDRDAEKRTKREALRGAKEQVEWLERQGERGGFSVVGADIAQSGNVRLYKARGSTPMTLFAVTFEGVLRIEDPALLAQTVRGGIGRAKALGFGLLSLARV
>NC_015170.1|WP_013623188.1|65874_66579_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MAILLLRLVAPMQAWGSRSRFDDRDTEAEPTKSGVLGLCAAALGIDRADPIDDLTRLRFGVRVDREGGAGRDYHTAQLKPGDPKTKTDVTTRFYLSDAAFWAGLEGEDRAFLQRLYAALHNPHWPLSLGRKAFQASLPIFAGPPQDTPLWEALQQAPSLRREPSEQAYRFVLDREAVPAERRAKASPSRRQDVPDGPFAHRHYLSREVLTLTGPLEVAPDPLVHRHWQAPEEVS
>NC_015170.1|WP_013623187.1|64380_65166_-|IS982-family-transposase
MGRPDLTLLPIHEALQVLSQWVKPHIPAKLLHKHEKISDADLIGIAILQMLHKQPYFSRWWHFLTVNHFPDLPSETQARIRLKRLLPVIEHLSHEVQALDFVAVDSEPLPVCTFKRAPRCKFRGARHGFSTAGPVFGFKLHAWCGLNGEIVAYNIRAANEHDYSVLCEMNRKWPAYGGPQQIGDKGYQSLTTITPPKVNARRPSPRWREEFGAARKCIESAFSVLVGAGLRWGQVKTMASLKLKVALHVLAHNLKYRDLIT
>NC_015170.1|WP_049775327.1|63730_64363_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MKAVLELHYLQNFAPSNLNRDDIGSPKDAFFGGTRRLRISSQSFKRAMRQDFAQRQILSEAELGLRSKRLLFSEDPREKGLVNRLVQGENALKTEEARFRAEFALLMNGIAFVEVKGEEDNYILDDTKSEALAFLGEYNLALLEKFLKSDSDEVQKASAVMREAREKLRKSKGYKGKIGESSAKEKLRKAISTALGSKKKELDEILNNRE
>NC_015170.1|WP_148232016.1|63089_63734_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MRELVRLERGKLAQLRRGLGGDNRSVYWLEGLYARTGYAEATPTGKEALRLVAGLYALKPKALDDGDEPEQSAETAPEAPRKAVSIGKQMGQLYLQQDRRPSTEKRFLALLDTDREGIGYHMRQVVTLLDTADLTPDWERLVTDLLYWSDRTRKGWAQDFYAEIFREENRQDDKTGGTLPSSDTSVGSPASAPLFASSQPDHQPADQDDEGETL
>NC_015170.1|WP_148232009.1|62776_63055_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MPAVTTFWQRLEAPFRQYLLNLDGDPEQATLEWNAALKQAAWQGWNIAQEAAGMNAVGLRAVQKSQGLLLKVLGGLPVPVQPVPATTENTDD
>NC_015170.1|WP_013613827.1|61607_62681_-|IS4-family-transposase
MNHLNQPPQDSLFTALRPFFRIDQRRFTVLVALILAIIQQRSVVLNNLKATITLPGSREMRYQRLLRFVQFLIPEEMYLKFALHVLGTDELTLILDRTNWKLGKRDVNILMLSAVWEGFSLPLMWRFLPHGGSSDQRIRKELMADFLRHCPQVHIDGLLADREFIGQDWFTFLSEHGIAPCIRLRSDTKMDSLPVHVFAKKMQVGEVRVWHSSMVVYGVRLRVLALKVSKTEMLYLAYKGRADQNLRKYALRWQCENLHAALKTRGFDLEATGLTQAERVSTLLMVIAISFIWCLRTGTVLLLEGNVETMKAKRQKAHGYASKSLFRLGLDELRDLLSHPSPENWNRLARLVPRFEG
>NC_015170.1|WP_148232015.1|60135_61668_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MVSFSLLRENWVPVLDLEGKTASVSLSDTLLTPQLYRRIDAGHPLHTAALYRLHLALLHRALGPSSAEDAAQWYSAGFPSEKVQAYLECYADRFDLFGPQPFMQVVGLDPASVGENFRSHWTRLSTEDGSPNTTALFNVEARPNGGRMDEITAAEAAVQLLSQQSFTLGGLIKRFTTSARAAPVATAALFLAEGHNLQQMLALNLVPYTASMAARDLPVWEQPPLTVADIQRIYADKEPKPRPAEGFVSRYAWPSRSILLLPEQTEGGLKVRTIGFGAGVPLAGAGEGAGANLDPMVGLLPSRDDKGDPYPYKLRRDRLLWRDLTALLPSPEVKVSEAKDGKGKKKVTAKPGRTAYVLEHAAEVMRLVQAQRQPAAPPVRPVVSQSQAAELDEPLPDAPAAPPVLPVVVFGQLTDQGKAFAIRQETYTLPQRFIENPEHFHDYIKGSLETATMVGNALWSAVKHLAEELLKKDGSRSPDPADIRKLSEQTDYPSKRGTSRARRFQFSGLG
>NC_015170.1|WP_013623192.1|68723_69962_-|hypothetical-protein
MKKQGLIYALLGLLMAGCSNGSSLPATPADSLETQARKAPKSTAPAPAPAPAPTPAPAPEPTAPAGPSTAQVRADGTLMVNGQAMFPMGFYHVSWAGDAERRLRDMHAIADLGFNTMNSTMFDPEVDLEGYRKLMDAAQARGMKMLVEDFNETSIRGLKDHPALLGWMVADDCNRLVSPEELQRRSESVKQLDANHLTYTSMAISFANSHTEYFGRADAVGNQSYPVDGGDPLNVVYPMMTRLVAEANAKGTLPIANLQSFRWEGGRYPTPAELNNMTNQAIAAGVKGILYYTYLDRTNDLASYTGLNDELRRLASEVKVLAPALTDGQRSELPVAASNRQATAHLWTYGSRRYVQVVSLDQTVSQSVKVQLPGTVGSLQPLFAGRTTSLTLQGTTAAGTLAPLASQWYELR
>NC_015170.1|WP_148232011.1|70265_71477_-|hypothetical-protein
MRPLFHSARRHGFSAAAPLLTLLLAAQLTGCQLLQPSPATAGGLAPDHRLQEAQSTSVTHRPDGTVLVNGQSFFPFGFYHVSWAWQGTPEGRVQDLQRLSQAGFNLMVTEPISDSDSANFTGLLDQAQQAGMFVIPYGLSPENRQRVLQHPALLGFKVADDANVQYTPQQVAERSAQFKALNPAKLTYFSLSVGQERPETPYFAAGDLIGNQSYPIGNDDIGVTYRMMQSAVQSAVAQGNVPIANLQSSFWGATKPTPAEVRNMTYQALLAGVKGIVYYAYRAPEVDLNAEPFLWKSLQGLSREVALLAPLLLDGELITLNSGTAHAPLAAYLRGQTSGGEWQGYLLTVNTSRRESQSVDLQLPEAPTRWERVGSAETATLRHDGPQVGGRLAPLQVAVVRVR
>NC_015170.1|WP_013623194.1|71612_72884_-|LCP-family-protein
MYQRQQVQQLGQEVYHELDGDGLPPLPGVLDDPVFAQLPPPPADRPVSWGRYQPPAATTAAATLPQEAQEAGPAAGSQTTGKSGPPQQEETEEEEPEQAETEQQETGEKQVAGSQAARSQAAGSQTTGRQGTSPVSPTGESLAAPAQQRPAADPAAPQKQAPASSGPVQAVTPPAAPSSFTERLKTRARLHILLIGNDEPELGTGRGDVLVVLTFDPVAQQLTFLSVPRDTRVRIPERDGQAKINAAYALGGPTLQTLAVEHFLGLPMDKFVEVSMNGFQRVIDLVGGVEVSPPFAFELDGQQFQPGRVQLNGEQALAYIRMRKQDPRGDLGRNERQQEVIRSLMASLAQRSPEELNALLQQLSTQVRTNFSPSEVVALRRTHAYAVDHQSVLRPAGENRRIDGQWYYVVSDRERQRLHLALR
>NC_015170.1|WP_169310714.1|73218_74472_+|oligosaccharide-flippase-family-protein
MLWTVAGQGVYSAAQWLMVIVLARSGGASDVGLYSLGLALTAPLFLLLGLQLRAVQATDAQGHFEFRDYAALRLPSMALGLAVTAVLAWLYPHASGPVWWLGVAKALEGGSDVMYGLMQQRERLDWIAQSTLLRGLLGLALLALIYRLTGDLTLATLGLALAGLATLLLFDLPRGRRLAAGRWWTWPPSSALLRLALPLGVVIGLVSLGTNLPRLFVERQLGREALGIYAALSYVTVAGSVFVVALGTALTTRLSQVFARGDRAGFVRLTLALMAGAGGVGLLLVLLSAVAGAPLLALLYGPAYAEHARTFFWLTLAGVAGYLASSLGFAVTAARRFREQLPLFAVVTAVLVLACWWLIPRYGLLGAAAATLIGTLAQLLGSWLIVRQALSGLSPGESGSPDASGPTSSPDSLPGAS
>NC_015170.1|WP_013623196.1|74472_75636_+|glycosyltransferase
MSFASTSSVLPQRPVRVLHLTGNLDRGGIETWLVNVFRRADPAAVQMDVLVASPAPHTGVYEAELRDLGVRIIHAPPSGNLPQFVQAYRRVLREYGPYDVVHSHIHHFGGLLLLLSRLAGVPVRVATSHTDTSQADQQAGRGRAAYLRAMRAALQGSVTHRTAVSQAAASALFGPDWASQPVQIITLGIDLAGLQTPRPVQGLRDELGLQPGVPVLGCVAQLRPEKNHMFLLDVLAEHVRRQGPAYLLLVGEGDERSAIEARVAELGLQPWVKLLGSRPDVAELLWLMDAFLLTSKFEGLSLAFIEAQAVGLPCIVSTGVPVTSDDRRFPLIDVVRLPLNGDPAPWADALAAVLERGRHDPPRMDFEVAETTRELTEFYIRASRGEV
>NC_015170.1|WP_041223126.1|75632_77006_+|O-antigen-ligase-family-protein
MSQPWPAQMAALPAAGRRTAPLLERAVIWLLGAFVAAQCFGLPLLGVGPWALWPTLADLLLWLALLLAALYRAPVQLDLRPIGQALAAVTALSALSVLLLFVMGDGRLDVALPFGVFQLFKLLQLLGVFWMAARLPLTQPVLAGWERAARFGFLVMVVTVVWTYFSPAIPQTLGQVLPRGLGVSGPWESYYLHNERGLGTLGYNHAHVAAMVLVQGALLMMLRPLKSNSWVLLGIVVACFLSGARAGLVGALVFVLLESVRTPLRSTVMVLLAGLLGLAALPYLEADLSSLIARQSTILEAGNAENLAGRGDIWQTYVQNLAADPVRLLLGSGMGSGIANNGSNAHMMVLQVLYETGIAGFSVMLLLFWGLMSRLYRLRERRAGIALNVLLGLWATTFATETLYPNSAFGSFLPLLALVMAVALTPASLETAGGEHSASLQERPAAGQPSRTLGWED
>NC_015170.1|WP_013623198.1|77009_78197_+|glycosyltransferase-family-4-protein
MRVSVVLEQRFIHTADGATYDNGHATYAHWQRYLSTFEEVQVVGRSQQVASVPPGYRRVDGPGVKVLQVPYYQGPLGLLRRLPAVLRTLRRGLEPEDAVIVRFSGLLGHLAAGLRQSQGRPFAAEVVNDPYMGYGPDGTRHPLRPLFRALLTGLTQLQCRQAGAVQYVTREALQRRYPPRRGRPSFGVSDVHLPPEAFQAAPRRYDRPARLAVLVGSLEQPHKAADVAIEALALLRRRGQDVRLSIVGDGPLRPSLEAQAAQAGVAEHLEFVGQRSTPAEVRADLAAAELFLIPSRTEGLPRVLLEAQAQALPAIGSSVGGIPELIPAEYLVPPGDAAALARVWGALAADPAALSAASARNLALARDYADDVLDRERSAFQRAVRSLLLPRKDSL
>NC_015170.1|WP_013623199.1|78193_79321_+|glycosyltransferase-family-4-protein
MKDRPQTILYTTTTAIASLAFFSEHFGHLRRQGWDVHSVTPAEPADQVQRAIDASGAAHHAVPFAREISPRRDLTALGQLLGVAARVRPDVINFSTPKAGLLGGLVGAALGVPLRVYFIHGLRSETAATGRLALLRPVLLMMERLTAACAHEVLCVSPSNRDEAVALGLVPASKIRVLGAGSPAGIPVERYAQPDPAAVAAAREELGLPEGTPVVGFVARMAPQKGTEELLLAWAQVHAQVPQARLLLVGVPDPANPLSDEAMRAFREAPGLVQVEFEKDMSRLYPLMTVHTLPSRHEGLGMVVLEAGAYGVPSVLTDASGVRDAGVADETCLQVPAGDVPALADALVRLLSDAALRERLGRQSQAWVSENFAQE
>NC_015170.1|WP_169310715.1|79307_79463_+|hypothetical-protein
MPRNKVWALWDDFYAEAWQKRQQAARAARPWKWAAAAGAAALMLGLARRSR
>NC_015170.1|WP_013623200.1|79571_80597_-|UDP-glucose-4-epimerase-GalE
MKVLVTGGAGYIGSTTCSALEDAGHTPVVLDSLVMGAREFTQGRTFYEGDVADSALVRQIFAEHPDIQATLHFAARIVVPESVEQPGLYYRENVLASLSLFETLLDLGQSRVIFSSSASVYASPPDYRVTETSPMAPMSPYARTKQMVEDILSDLCTAAAQAGQPLRGIALRYFNPVGADPQGRSGPYLEDPSHLLGRLVSAARGSGEFSITGTDYPTRDGTGLRDYIHVWDLAQAHVAALENFDQAFERAREELGQEVNSLIINVGTGNGVTVRELVDAFSRISPQPLRVTEAPRRPGDNAGAYADIGRAQRWLDWSPQRTTDDALRTALDWAEQWNSRR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015170_1	1.1\|5433\|37\|NC_015170\|CRT	5433-5469	37	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	5433-5469	0	1.0
NC_015170_1	1.3\|5579\|36\|NC_015170\|CRT	5579-5614	36	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	5579-5614	0	1.0
NC_015170_1	1.4\|5636\|47\|NC_015170\|CRT	5636-5682	47	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	5636-5682	0	1.0
NC_015170_1	1.5\|5704\|44\|NC_015170\|CRT	5704-5747	44	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	5704-5747	0	1.0
NC_015170_2	2.1\|53462\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53462-53494	33	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	53462-53494	0	1.0
NC_015170_2	2.2\|53523\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53523-53555	33	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	53523-53555	0	1.0
NC_015170_2	2.3\|53584\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53584-53616	33	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	53584-53616	0	1.0
NC_015170_2	2.4\|53645\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53645-53677	33	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	53645-53677	0	1.0
NC_015170_2	2.5\|53706\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53706-53738	33	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	53706-53738	0	1.0
NC_015170_3	3.1\|68615\|31\|NC_015170\|CRISPRCasFinder	68615-68645	31	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	68615-68645	0	1.0
NC_015170_1	1.3\|5579\|36\|NC_015170\|CRT	5579-5614	36	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	5604-5639	6	0.833
NC_015170_3	3.1\|68615\|31\|NC_015170\|CRISPRCasFinder	68615-68645	31	NC_012849	Ralstonia pickettii 12D plasmid pRp12D02, complete sequence	251093-251123	6	0.806
NC_015170_1	1.2\|5491\|67\|NC_015170\|CRT	5491-5557	67	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	5491-5557	7	0.896
NC_015170_2	2.1\|53462\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53462-53494	33	MH834620	Arthrobacter phage Melons, complete genome	10832-10864	7	0.788
NC_015170_2	2.1\|53462\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53462-53494	33	MH834606	Arthrobacter phage Coral, complete genome	10671-10703	7	0.788
NC_015170_2	2.1\|53462\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53462-53494	33	MH834618	Arthrobacter phage Lunar, complete genome	10832-10864	7	0.788
NC_015170_2	2.1\|53462\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53462-53494	33	MN234214	Arthrobacter phage Amelia, complete genome	10832-10864	7	0.788
NC_015170_2	2.1\|53462\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53462-53494	33	MH834624	Arthrobacter phage Polka, complete genome	10674-10706	7	0.788
NC_015170_2	2.1\|53462\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53462-53494	33	MH834608	Arthrobacter phage Cote, complete genome	10832-10864	7	0.788
NC_015170_2	2.1\|53462\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53462-53494	33	MH834616	Arthrobacter phage Kepler, complete genome	10670-10702	7	0.788
NC_015170_2	2.1\|53462\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53462-53494	33	MH834609	Arthrobacter phage Daob, complete genome	10835-10867	7	0.788
NC_015170_2	2.2\|53523\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53523-53555	33	KY945355	Mycobacterium phage Shandong1, complete genome	11585-11617	8	0.758
NC_015170_3	3.1\|68615\|31\|NC_015170\|CRISPRCasFinder	68615-68645	31	NZ_LR594663	Variovorax sp. RA8 plasmid 2	102499-102529	8	0.742
NC_015170_2	2.2\|53523\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53523-53555	33	NC_023286	Streptomyces sp. F12 plasmid pFRL6, complete sequence	38904-38936	9	0.727
NC_015170_3	3.1\|68615\|31\|NC_015170\|CRISPRCasFinder	68615-68645	31	NZ_CP053023	Sphingobium yanoikuyae strain YC-XJ2 plasmid p-B-Sy, complete sequence	193139-193169	9	0.71
NC_015170_3	3.1\|68615\|31\|NC_015170\|CRISPRCasFinder	68615-68645	31	NZ_CP013266	Sphingobium baderi strain DE-13 plasmid pDE2, complete sequence	12971-13001	9	0.71
NC_015170_2	2.2\|53523\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53523-53555	33	NC_004680	Mycobacterium phage Che8, complete genome	21503-21535	10	0.697
NC_015170_2	2.2\|53523\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53523-53555	33	AY129330	Mycobacterium virus Che8, complete genome	21503-21535	10	0.697
NC_015170_2	2.2\|53523\|33\|NC_015170\|PILER-CR,CRISPRCasFinder,CRT	53523-53555	33	KY385384	Mycobacterium phage SimranZ1, complete genome	21333-21365	10	0.697
NC_015170_1	1.5\|5704\|44\|NC_015170\|CRT	5704-5747	44	NC_015170	Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence	5769-5812	13	0.705

1. spacer 1.1|5433|37|NC_015170|CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 0, identity: 1.0

cggaccggaaaaggtccaaagaacgctgcaagcaata	CRISPR spacer
cggaccggaaaaggtccaaagaacgctgcaagcaata	Protospacer
*************************************

2. spacer 1.3|5579|36|NC_015170|CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 0, identity: 1.0

gcgtttcgataccgatacctttgggccgttttgata	CRISPR spacer
gcgtttcgataccgatacctttgggccgttttgata	Protospacer
************************************

3. spacer 1.4|5636|47|NC_015170|CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 0, identity: 1.0

tggaggaatgggggtttatgccgtgccggacaaggtttttcctacgg	CRISPR spacer
tggaggaatgggggtttatgccgtgccggacaaggtttttcctacgg	Protospacer
***********************************************

4. spacer 1.5|5704|44|NC_015170|CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 0, identity: 1.0

ggcttccattcccgacacctttgggccgtttgaccatttctttc	CRISPR spacer
ggcttccattcccgacacctttgggccgtttgaccatttctttc	Protospacer
********************************************

5. spacer 2.1|53462|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 0, identity: 1.0

ccaacgccgaaaacgccgccgagtttagcgccc	CRISPR spacer
ccaacgccgaaaacgccgccgagtttagcgccc	Protospacer
*********************************

6. spacer 2.2|53523|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 0, identity: 1.0

cggcacccagcgcggcccggtggccctggagta	CRISPR spacer
cggcacccagcgcggcccggtggccctggagta	Protospacer
*********************************

7. spacer 2.3|53584|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 0, identity: 1.0

tacgcggcggcgtttaaggggcggaagcaggtc	CRISPR spacer
tacgcggcggcgtttaaggggcggaagcaggtc	Protospacer
*********************************

8. spacer 2.4|53645|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 0, identity: 1.0

tgccgaatcagaatcctgagagggtgacgaggc	CRISPR spacer
tgccgaatcagaatcctgagagggtgacgaggc	Protospacer
*********************************

9. spacer 2.5|53706|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 0, identity: 1.0

ttccccaagactgatgccgtggctgaaggttac	CRISPR spacer
ttccccaagactgatgccgtggctgaaggttac	Protospacer
*********************************

10. spacer 3.1|68615|31|NC_015170|CRISPRCasFinder matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 0, identity: 1.0

acatccaggcccggcgcttcattgttcgtgg	CRISPR spacer
acatccaggcccggcgcttcattgttcgtgg	Protospacer
*******************************

11. spacer 1.3|5579|36|NC_015170|CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 6, identity: 0.833

gcgtttcgataccgatacctttgggccgttttgata	CRISPR spacer
ccgttttgataccgacacctttgggccgtttttgga	Protospacer
 *****.********.**************** . *

12. spacer 3.1|68615|31|NC_015170|CRISPRCasFinder matches to NC_012849 (Ralstonia pickettii 12D plasmid pRp12D02, complete sequence) position: , mismatch: 6, identity: 0.806

acatccaggcccggcgcttcattgttcgtgg	CRISPR spacer
acatccacgccctgcgcttcattgggcgggc	Protospacer
******* **** ***********  ** *

13. spacer 1.2|5491|67|NC_015170|CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 7, identity: 0.896

tttgtggaactttccatacccagccttttcttcgtcctatacacatttttttgcccaatg	CRISPR spacer
tttgtggaactttccatacccagccttttcttcgtcctatacacatttttttgcccaatg	Protospacer
************************************************************

14. spacer 2.1|53462|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to MH834620 (Arthrobacter phage Melons, complete genome) position: , mismatch: 7, identity: 0.788

ccaacgccgaaaacgccgccgagtttagcgccc	CRISPR spacer
cgaacgccgaaaaagccgccgaggttttggcca	Protospacer
* *********** ********* **   ***

15. spacer 2.1|53462|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to MH834606 (Arthrobacter phage Coral, complete genome) position: , mismatch: 7, identity: 0.788

ccaacgccgaaaacgccgccgagtttagcgccc	CRISPR spacer
cgaacgccgaaaaagccgccgaggttttggcca	Protospacer
* *********** ********* **   ***

16. spacer 2.1|53462|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to MH834618 (Arthrobacter phage Lunar, complete genome) position: , mismatch: 7, identity: 0.788

ccaacgccgaaaacgccgccgagtttagcgccc	CRISPR spacer
cgaacgccgaaaaagccgccgaggttttggcca	Protospacer
* *********** ********* **   ***

17. spacer 2.1|53462|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to MN234214 (Arthrobacter phage Amelia, complete genome) position: , mismatch: 7, identity: 0.788

ccaacgccgaaaacgccgccgagtttagcgccc	CRISPR spacer
cgaacgccgaaaaagccgccgaggttttggcca	Protospacer
* *********** ********* **   ***

18. spacer 2.1|53462|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to MH834624 (Arthrobacter phage Polka, complete genome) position: , mismatch: 7, identity: 0.788

ccaacgccgaaaacgccgccgagtttagcgccc	CRISPR spacer
cgaacgccgaaaaagccgccgaggttttggcca	Protospacer
* *********** ********* **   ***

19. spacer 2.1|53462|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to MH834608 (Arthrobacter phage Cote, complete genome) position: , mismatch: 7, identity: 0.788

ccaacgccgaaaacgccgccgagtttagcgccc	CRISPR spacer
cgaacgccgaaaaagccgccgaggttttggcca	Protospacer
* *********** ********* **   ***

20. spacer 2.1|53462|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to MH834616 (Arthrobacter phage Kepler, complete genome) position: , mismatch: 7, identity: 0.788

ccaacgccgaaaacgccgccgagtttagcgccc	CRISPR spacer
cgaacgccgaaaaagccgccgaggttttggcca	Protospacer
* *********** ********* **   ***

21. spacer 2.1|53462|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to MH834609 (Arthrobacter phage Daob, complete genome) position: , mismatch: 7, identity: 0.788

ccaacgccgaaaacgccgccgagtttagcgccc	CRISPR spacer
cgaacgccgaaaaagccgccgaggttttggcca	Protospacer
* *********** ********* **   ***

22. spacer 2.2|53523|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to KY945355 (Mycobacterium phage Shandong1, complete genome) position: , mismatch: 8, identity: 0.758

cggcacccagcgcggcccggtggccctggagta	CRISPR spacer
cggcgccctgcgcggcccggtggcgacgcaggc	Protospacer
****.*** ***************  .* **

23. spacer 3.1|68615|31|NC_015170|CRISPRCasFinder matches to NZ_LR594663 (Variovorax sp. RA8 plasmid 2) position: , mismatch: 8, identity: 0.742

acatccaggcccggcgcttcattgttcgtgg	CRISPR spacer
gcatccaggcccggcgtctcattgcgcctcc	Protospacer
.***************..******. * *

24. spacer 2.2|53523|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to NC_023286 (Streptomyces sp. F12 plasmid pFRL6, complete sequence) position: , mismatch: 9, identity: 0.727

cggcacccagcgcggcccggtggccctggagta	CRISPR spacer
ggcgggccagcgcggccgggtggccccggacga	Protospacer
 *  . *********** ********.***  *

25. spacer 3.1|68615|31|NC_015170|CRISPRCasFinder matches to NZ_CP053023 (Sphingobium yanoikuyae strain YC-XJ2 plasmid p-B-Sy, complete sequence) position: , mismatch: 9, identity: 0.71

acatccaggcccggcgcttcattgttcgtgg	CRISPR spacer
acatgcagggccggcgcttcattgagaagac	Protospacer
**** **** **************   . .

26. spacer 3.1|68615|31|NC_015170|CRISPRCasFinder matches to NZ_CP013266 (Sphingobium baderi strain DE-13 plasmid pDE2, complete sequence) position: , mismatch: 9, identity: 0.71

acatccaggcccggcgcttcattgttcgtgg	CRISPR spacer
acatgcagggccggcgcttcattgagaagac	Protospacer
**** **** **************   . .

27. spacer 2.2|53523|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to NC_004680 (Mycobacterium phage Che8, complete genome) position: , mismatch: 10, identity: 0.697

cggcacccagcgcggcccggtggccctggagta	CRISPR spacer
actcacccagcccgggccggtggccctcatctg	Protospacer
   ******** *** *********** .  *.

28. spacer 2.2|53523|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to AY129330 (Mycobacterium virus Che8, complete genome) position: , mismatch: 10, identity: 0.697

cggcacccagcgcggcccggtggccctggagta	CRISPR spacer
actcacccagcccgggccggtggccctcatctg	Protospacer
   ******** *** *********** .  *.

29. spacer 2.2|53523|33|NC_015170|PILER-CR,CRISPRCasFinder,CRT matches to KY385384 (Mycobacterium phage SimranZ1, complete genome) position: , mismatch: 10, identity: 0.697

cggcacccagcgcggcccggtggccctggagta	CRISPR spacer
gctcacccagcccgggccggtggccctcatctg	Protospacer
   ******** *** *********** .  *.

30. spacer 1.5|5704|44|NC_015170|CRT matches to NC_015170 (Deinococcus proteolyticus MRP plasmid pDEIPR03, complete sequence) position: , mismatch: 13, identity: 0.705

ggcttccattcccgacacctttgggccgtttgaccatttctttc	CRISPR spacer
ggcctccattcccgacacctttgggccgttttggtgccagaatg	Protospacer
***.*************************** . ....    *

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NC_015169

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_015169_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_015169_1

197312-198572

Orphan

I-C

Consensus_repeat	Method
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CRISPRCasFinder
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CRT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	PILER-CR

17 spacers

The CRISPR arrays of NC_015169_1

>merge|NC_015169|1|197312-198572|CRISPRCasFinder,CRT,PILER-CR
CTATGGCGTTGTATCCAGCCCGAAGGCCGGGTGCAACCTGCTGACCAGCGGCGAGGCGCTGACCCCGCAGGAAAGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACGGTTTTGTGCGGGCCTATTCGCCAAGCATCATTCATGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACACGCTGATTCCAGGCACAGATAAGGTCTACATCCCTGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACAAGATGGTCTGATATATAAAGGATTTTAGAGAAGGTGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACGACAGCGAGAGTCTTCCGGCCGCCCCCGTACGGCCGGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACGCGGGCGAAGAGCAGGCCGACCAGCTCTACAACGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACCGCCGCAGGGGCAGAAGAAGGAGCATGTACCCAGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACGCCCGTGTCTGGCTCAGGCGGCGGCGCAGCACTTCGGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACGCGGATTTTTCCGCCGACCTGCTGAAACTGAAAAACGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACCAGACCCGCGCCAGCAGCGCCGCCAGCGCGGCCGCGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACTTCAAGAGTGAGGCGGCTGGCCCAACGAGGCATGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACTTTGACGTACGGCTTGCCGGTGGGCACCGCCAGGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACCAAGATTGAGAGCGCACGCATAGAAAACCCGTTTAGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACGCTATTCATTCAGCCCGAAGTGAGGTTTGACTCGTGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACATCACCGGCAGGGCGGGCGGGGCGGCCGCAGAGCGGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACCGGCCCGGAGTGCTGCCACATGCTGATCGCGGAGGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAACGTAGGTGAGGGTGTACTCACGCTCGAACACCTTTTTGTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC

>NC_015169|1|1|197312-198572|CRISPRCasFinder
CTATGGCGTTGTATCCAGCCCGAAGGCCGGGTGCAAC	CTGCTGACCAGCGGCGAGGCGCTGACCCCGCAGGAAA
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GGTTTTGTGCGGGCCTATTCGCCAAGCATCATTCAT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	ACGCTGATTCCAGGCACAGATAAGGTCTACATCCCT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	AAGATGGTCTGATATATAAAGGATTTTAGAGAAGGT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GACAGCGAGAGTCTTCCGGCCGCCCCCGTACGGCCG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCGGGCGAAGAGCAGGCCGACCAGCTCTACAAC
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CGCCGCAGGGGCAGAAGAAGGAGCATGTACCCA
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCCCGTGTCTGGCTCAGGCGGCGGCGCAGCACTTCG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCGGATTTTTCCGCCGACCTGCTGAAACTGAAAAAC
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CAGACCCGCGCCAGCAGCGCCGCCAGCGCGGCCGC
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	TTCAAGAGTGAGGCGGCTGGCCCAACGAGGCAT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	TTTGACGTACGGCTTGCCGGTGGGCACCGCCAG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CAAGATTGAGAGCGCACGCATAGAAAACCCGTTTA
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCTATTCATTCAGCCCGAAGTGAGGTTTGACTCGT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	ATCACCGGCAGGGCGGGCGGGGCGGCCGCAGAGCG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CGGCCCGGAGTGCTGCCACATGCTGATCGCGGAG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GTAGGTGAGGGTGTACTCACGCTCGAACACCTTTTT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC

>NC_015169|1|1|197312-198572|CRT
CTATGGCGTTGTATCCAGCCCGAAGGCCGGGTGCAAC	CTGCTGACCAGCGGCGAGGCGCTGACCCCGCAGGAAA
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GGTTTTGTGCGGGCCTATTCGCCAAGCATCATTCAT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	ACGCTGATTCCAGGCACAGATAAGGTCTACATCCCT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	AAGATGGTCTGATATATAAAGGATTTTAGAGAAGGT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GACAGCGAGAGTCTTCCGGCCGCCCCCGTACGGCCG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCGGGCGAAGAGCAGGCCGACCAGCTCTACAAC
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CGCCGCAGGGGCAGAAGAAGGAGCATGTACCCA
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCCCGTGTCTGGCTCAGGCGGCGGCGCAGCACTTCG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCGGATTTTTCCGCCGACCTGCTGAAACTGAAAAAC
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CAGACCCGCGCCAGCAGCGCCGCCAGCGCGGCCGC
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	TTCAAGAGTGAGGCGGCTGGCCCAACGAGGCAT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	TTTGACGTACGGCTTGCCGGTGGGCACCGCCAG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CAAGATTGAGAGCGCACGCATAGAAAACCCGTTTA
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCTATTCATTCAGCCCGAAGTGAGGTTTGACTCGT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	ATCACCGGCAGGGCGGGCGGGGCGGCCGCAGAGCG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CGGCCCGGAGTGCTGCCACATGCTGATCGCGGAG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GTAGGTGAGGGTGTACTCACGCTCGAACACCTTTTT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC

>NC_015169|1|1|197386-198572|PILER-CR
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GGTTTTGTGCGGGCCTATTCGCCAAGCATCATTCAT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	ACGCTGATTCCAGGCACAGATAAGGTCTACATCCCT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	AAGATGGTCTGATATATAAAGGATTTTAGAGAAGGT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GACAGCGAGAGTCTTCCGGCCGCCCCCGTACGGCCG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCGGGCGAAGAGCAGGCCGACCAGCTCTACAAC
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CGCCGCAGGGGCAGAAGAAGGAGCATGTACCCA
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCCCGTGTCTGGCTCAGGCGGCGGCGCAGCACTTCG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCGGATTTTTCCGCCGACCTGCTGAAACTGAAAAAC
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CAGACCCGCGCCAGCAGCGCCGCCAGCGCGGCCGC
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	TTCAAGAGTGAGGCGGCTGGCCCAACGAGGCAT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	TTTGACGTACGGCTTGCCGGTGGGCACCGCCAG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CAAGATTGAGAGCGCACGCATAGAAAACCCGTTTA
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GCTATTCATTCAGCCCGAAGTGAGGTTTGACTCGT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	ATCACCGGCAGGGCGGGCGGGGCGGCCGCAGAGCG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	CGGCCCGGAGTGCTGCCACATGCTGATCGCGGAG
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC	GTAGGTGAGGGTGTACTCACGCTCGAACACCTTTTT
GTTTCAATCCTCACCCAGCCCGAAGGCCGGGTGCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_015169.1\|WP_013623054.1\|195602_195962_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl\|CDD\|224694
NC_015169.1\|WP_013623045.1\|185185_186457_-\|PDZ-domain-containing-protein	unknown	unknown	gnl\|CDD\|223864
NC_015169.1\|WP_013623052.1\|192275_193322_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|275027
NC_015169.1\|WP_013623057.1\|199653_200586_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NC_015169.1\|WP_013623051.1\|192007_192283_-\|thioredoxin	unknown	unknown	gnl\|CDD\|379034
NC_015169.1\|WP_013623065.1\|209345_212516_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|224428
NC_015169.1\|WP_013623062.1\|206216_207470_+\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|366228
NC_015169.1\|WP_013623061.1\|205319_206138_+\|hypothetical-protein	unknown	unknown	unknown
NC_015169.1\|WP_013623049.1\|189994_190762_-\|3-hydroxybutyrate-dehydrogenase	unknown	unknown	gnl\|CDD\|211705
NC_015169.1\|WP_013623053.1\|193429_195517_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|211905
NC_015169.1\|WP_013623046.1\|186453_187377_-\|hypothetical-protein	unknown	unknown	unknown
NC_015169.1\|WP_013623055.1\|196235_197240_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271175
NC_015169.1\|WP_013623047.1\|187373_188456_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|183212
NC_015169.1\|WP_148231955.1\|198775_199636_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225117
NC_015169.1\|WP_013623064.1\|208384_209362_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_015169.1\|WP_013623059.1\|203107_203962_+\|isochorismatase-family-protein	unknown	unknown	gnl\|CDD\|163356
NC_015169.1\|WP_013623050.1\|190886_191831_-\|DUF808-domain-containing-protein	unknown	unknown	gnl\|CDD\|377542
NC_015169.1\|WP_013623063.1\|207503_208274_-\|DUF554-domain-containing-protein	unknown	unknown	gnl\|CDD\|377371
NC_015169.1\|WP_148231968.1\|204024_204885_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|224423
NC_015169.1\|WP_013623058.1\|200662_202114_-\|arginine-ornithine-antiporter	unknown	unknown	gnl\|CDD\|163522

Protein	Function_ID	Function_description	E-value
NC_015169.1\|WP_013623054.1\|195602_195962_-\|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl\|CDD\|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	3.90061e-31
NC_015169.1\|WP_013623045.1\|185185_186457_-\|PDZ-domain-containing-protein	gnl\|CDD\|223864	COG0793, Prc, Periplasmic protease [Cell envelope biogenesis, outer membrane].	9.76627e-47
NC_015169.1\|WP_013623057.1\|199653_200586_+\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.86931e-15
NC_015169.1\|WP_013623051.1\|192007_192283_-\|thioredoxin	gnl\|CDD\|379034	pfam13098, Thioredoxin_2, Thioredoxin-like domain.	0.000156577
NC_015169.1\|WP_013623065.1\|209345_212516_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	1.44939e-72
NC_015169.1\|WP_013623062.1\|206216_207470_+\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|366228	pfam00657, Lipase_GDSL, GDSL-like Lipase/Acylhydrolase.	1.94302e-09
NC_015169.1\|WP_013623049.1\|189994_190762_-\|3-hydroxybutyrate-dehydrogenase	gnl\|CDD\|211705	TIGR01963, D-beta-hydroxybutyrate_dehydrogenase, 3-hydroxybutyrate dehydrogenase. This model represents a subfamily of the short chain dehydrogenases. Characterized members so far as 3-hydroxybutyrate dehydrogenases and are found in species that accumulate ester polmers called polyhydroxyalkanoic acids (PHAs) under certain conditions. Several members of the family are from species not known to accumulate PHAs, including Oceanobacillus iheyensis and Bacillus subtilis. However, polymer formation is not required for there be a role for 3-hydroxybutyrate dehydrogenase; it may be members of this family have the same function in those species.	1.42049e-103
NC_015169.1\|WP_013623053.1\|193429_195517_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|211905	TIGR04170, RNR_1b_NrdE, ribonucleoside-diphosphate reductase, class 1b, alpha subunit. Members of this family are NrdE, the alpha subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron.	0
NC_015169.1\|WP_013623052.1\|192275_193322_-\|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl\|CDD\|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	4.62657e-139
NC_015169.1\|WP_013623055.1\|196235_197240_+\|site-specific-integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	7.06451e-23
NC_015169.1\|WP_013623047.1\|187373_188456_-\|oxidoreductase	gnl\|CDD\|183212	PRK11579, PRK11579, putative oxidoreductase; Provisional.	4.17987e-122
NC_015169.1\|WP_148231955.1\|198775_199636_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.41297e-32
NC_015169.1\|WP_013623064.1\|208384_209362_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.67533e-27
NC_015169.1\|WP_013623059.1\|203107_203962_+\|isochorismatase-family-protein	gnl\|CDD\|163356	TIGR03614, RutB, pyrimidine utilization protein B.	6.52184e-37
NC_015169.1\|WP_013623050.1\|190886_191831_-\|DUF808-domain-containing-protein	gnl\|CDD\|377542	pfam05661, DUF808, Protein of unknown function (DUF808). This family consists of several bacterial proteins of unknown function.	4.07733e-148
NC_015169.1\|WP_013623063.1\|207503_208274_-\|DUF554-domain-containing-protein	gnl\|CDD\|377371	pfam04474, DUF554, Protein of unknown function (DUF554). Family of uncharacterized prokaryotic proteins. Multiple predicted transmembrane regions suggest that the region is membrane associated.	7.60953e-69
NC_015169.1\|WP_148231968.1\|204024_204885_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	3.11684e-26
NC_015169.1\|WP_013623058.1\|200662_202114_-\|arginine-ornithine-antiporter	gnl\|CDD\|163522	TIGR03810, arginine-ornithine_antiporter, arginine-ornithine antiporter. Members of this protein family are the arginine/ornithine antiporter, ArcD. This exchanger of ornithine for arginine occurs in a system with arginine deiminase, ornithine carbamoyltransferase, and carbamate kinase, with together turn arginine to ornithine with the generation of ATP and release of CO2. [Transport and binding proteins, Amino acids, peptides and amines].	0

>NC_015169.1|WP_013623055.1|196235_197240_+|site-specific-integrase
MTPSHALEQYKGDLLSSTREWTNLHDDELKRRAVRAAGDKDSAELVSLTTAYLAHGGSSGVLTSPRTVEAYQLGTRQFVEYAEQNAVSLLKPGRHMAQGYVNWMLAQGRKPAGVQLKVAAAGCLYRALRWAGATEADPFRDVRVPKDRTPGIIKRPPYTESEIADVLEGADVHIRFLLFVTAHGGLRISEALALEWDDIDEDARRIHVRSGKGRKARMVAMSQSLSEAARAYRVTHGPGGPEFGAGRRATPPQRVFRYGTAPTARYHLERAFKAAGVEFRGFHPGRKYAGTRLLQQIKDFGRVAAHLGHESVDTTRKGYARLAADDLKDDLAGW
>NC_015169.1|WP_013623054.1|195602_195962_-|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MQLIYDTLTGNTRRFAHKVADLTGLEAVALKEASPQEPYLLLTYTFGSGAVPDTTRAFLQVHAPLMRGVVSSGSFHWGENFGRAGEVIAGAYGVPFVMRVNKSGNLSDARAVAEWVRAQ
>NC_015169.1|WP_013623053.1|193429_195517_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MERWIELNNKVLSGTEINTTYDTDALQVYFQEKVNPNTVFFHDLKEKIRYMTENGVWDASLFERYSYDEVQQVFNRAYGYKFRFKSFMGAYKFYSEYATMTPDRSRWLERYEDRMSITALARSSNVEEALELVHHLVNQTFTPATPTLMNSGKANTGRLVSCFLLQDCTDNLNSITKTLSFVAELSKGGGGIGVEVSNLRARGESLRGIQNVTKGVMGVAKMLDNMLRYADQAGQRPGAGAIYLSVMHADFMDVLSAKKIASDEDSRLKTLSVGATIPDIFMQKVRSGEDIYQFYPYSIEQETGREFTSIDWNEEYQALADNPRIRKKRVSARRVFEDIAITQGESGYPYLLFEGNANRANPIPNVGKILMSNLCSEILQPTRPSYFHPYGEEHKDRIGLDVSCNLSSLVIEQTMRSGDMGRVVGAAIRMLDDVARSTSVTEVPAVKRANDEMRSIGLGAMGLHSFLAKNELIYGSEEALDFVDTFFAAVHYHARKASMEIARDTGFVFAGFEGSRYADGSYFEQYLAKDFTPKTAEVAALFEGHTLPTKEDWAQLVRDIQQHGLAHSFVMAIAPTGSISYVSHASASIMPITEKVETRTSNKARTIYPMPHLNVDTEWYYEEAYDMDMNRVLDTVATAQRHVDQGISCTLFVPGTCSTRDLQRYYIQAYLKGVKTLYYTRMRKTTIEECLTCAV
>NC_015169.1|WP_013623052.1|192275_193322_-|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MHPHTDPFSATNWSEPEDGFSATFYEKYTSQLWFPEEIPLSNDAIVWKSLSEAERWTYIHASAGLNALDTLQGEVGMPALRHLVDGHIRKATIQFQGMMEDIHAKSYSLMNKTFLTTSEEREVFEWVRTQPQLQNKIAMIREIYDNPDVSNLGLWKKMVVSCMLETALFYSGFFYPLYLAGQGRMVSAGEIFNLIIMDEAVHGVYVALLAQEKFAEMNEAEQAYALAWYEETLMKLYRNELAYTEMLYADVGLVDEVKKFIRYNCNVLADNLGVERSFEDEEINPIVRNGIKAKGTTHDFFSAKGNSYAKIAVEALTEDDLDDIWPEPRRVTRKESARPAHLEALAHD
>NC_015169.1|WP_013623051.1|192007_192283_-|thioredoxin
MTEPAVQTRFVLLTQDNCPNCERLKLMLAKPLRGQFDDQIVTVHREQAASEFEALAAEYSVQSTPALIDRERGEVLRNTGGLGEVKNFLTA
>NC_015169.1|WP_013623050.1|190886_191831_-|DUF808-domain-containing-protein
MSGGLVALLDDIAVIARAAAASVDDVAAAAGRAGAKTVGVVVDDAAVTPRYVTGFSPARELPIIWKIAKGSLRNKVVFILPAVLLLSQFLPSAITYVLMLGGTYLCFEGAEKVYEAFAGGHHATEEEQVADLSSEEHEQQMVSGAIRTDLILSAEIMAIALAEVANEPLMSRTLILLVVALLITALVYGVVGLIVKMDDIGLKLSQSPQGGVAAFGRGLVKAMPHVLTALSVIGTAAMLWVGGHIIVAGLAKLGFPELEHLIHDFAVQAAHMVPAAHALVEWLVGTIGSGLFGLLVGFSIVGLLHLLPRRGAAH
>NC_015169.1|WP_013623049.1|189994_190762_-|3-hydroxybutyrate-dehydrogenase
MQTTERRVALVTGGTSGIGLAIAKRLQEDGLQVAALDLDRPEARSVAEEHGLCFVGADLAQRAECRRAVEETVQALGGLDVLVNNAGFQHIDPIRDFPEDTWDTMLHVMLTAPFLLSRYAWDHLTRSGQGRIVNVASIHGHVASPFKSAYVSAKHGLIGLTRTAALEAGEQGLTVNAICPGYVRTPLVESQLADQARTRGISVEEVEQRVMLEPAAIKRLLDPADIAALASYVVSPAAWGMTGAVLDLDLGWTAR
>NC_015169.1|WP_013623047.1|187373_188456_-|oxidoreductase
MSAATPLRTALLGYGSVSQVFHVPLLRALPEFRLVAAASQNPQTPAALPEAQVFATPEALLAGSDAELVVVATPNRTHFALARAALESGRHVLVEKPFTLTVGEAQALVTLAQERGLVLSVFQNRRWDGDFLTLQQVLAGRELGRVTALHSHFDRFRPQVRDRWRESDEPGAGIWYDLGPHLVDQALTLFGLPRRVRADLARMRSGARSDDHAEVTLDYSDTGGERRVTLHASMLTAYAAPRFVAHGTAGSFVIEGLDPQEEALKAGETPGAPGWGLGAPDGRLFSGQGERAVPRLPGDYPAFYRALAAAIREGSPPPVTPQQALDTMRVLVAAQRSQDQGGWVSLEPAAPPARALDSDL
>NC_015169.1|WP_013623046.1|186453_187377_-|hypothetical-protein
MNTLLPGLRALTLTPTLAPMLALALCFPVLGSLPARAAPAQAAPTPTFRTPALSPAADRTAAGAARLSASALLERARQAAGLPQSGLTLLHERVQISESGERGGAPTYLSDVWTDLAGQRLKMTDYTGDTLDSVHLLTPAASLLYTPQHGTVPVPPQRAEILRWNLRSGVGGLGAASQRGVRLRAAGTQTWLEDGPQPLRGAVLEVTWPDGAAWQYLLDPQTGRLLADRSADKDLGLLTFTYSDPRAASAVKVLPGGAPQALEERTLLLPGGEVLYREQVLTRELNPALPPRTFELPQLPQASGRAQ
>NC_015169.1|WP_013623045.1|185185_186457_-|PDZ-domain-containing-protein
MRLSAAPRLVSPLLAALLLAPAAAAAPQEQSEISAQDLFDEVIYELALNYGGPSDVRAQDLRERFLPRVQALCAGQNVCSSKAAYPPIGQLLRELNDEHTNFFSPAQWAAMQLESSGQASGRAFGLVTRLVEGQGTLVTEVLPGSPAAQAGLRAGDLLTRMGHMPLLSGLAGEKLGAAGRSGQVTELTYSRAGQSRQTELAGAAFVAPPVSLEMLDGRTALLRVRHFDVRGVAQDLHNALRRAQQQGAERAVLDLRGNPGGLLPETVLSTGALTQPAPLLDVERSVSTLHSYDQGRYLMDGQPQPGTRVFKPQRFTGPLAVLVDQDSASGAEFMARDLLSRPQTVVLGRPTVGVGDSATQLLDLADGSGLQVTVSRVQTAAGQPLSASVQPQVLLKRDDLTFARTGEDPELASALRALDSLKP
>NC_015169.1|WP_148231955.1|198775_199636_-|helix-turn-helix-domain-containing-protein
MSAGSVLNEKPSGPAGFGILGGVPAAVPRPFGSASAAVSPQLLAALLSPAHASPLEALLDTQPDLIFYVKDSQGRYVMVNEALRRRSGRAMKSDLLGRTAAEVFTGEVGERTQLQDEQTLQLGQELHDVLEFYLTAQGTPVWCLTDKLPLRGGSGEVLGLVGLSRDLPPASQHAEFPRVASALAYIHAHFADGSLRLRDVAAHVGLSADTLERLFRRVTHLTPKQLLLRVRFDHAVRLLRRPELSVSEVAHACGYSDHSAFTRKFRRMAGISPQAYRRRLRELGQL
>NC_015169.1|WP_013623057.1|199653_200586_+|DMT-family-transporter
MLERPSLFPRLQTLPAEWVGVGLALFSASASATVGIWAKMGAAAGLSTSSMLSWRFGLLAALLFALGYAKVSREQLRPLLLMGLLHVGSTLAYFTALEHISASTTALLVYCAPAVVIVLGLLAHIRPSRWQVIALTVTLLGLTVVVGMPGPADASTVGLAMGGLAGLMYGGYFFASHRLNRGIKPLAVTAIVSLVTAAVAAGMGAMQGDLGVPHGWGQWLPVLGLALIPSLISMPTLYGAVARIGATRTSMLTTTDPLWAIALAVLLLGEHLSAGQLLGGALILAGACLAQRESKPAKRRVRRGKFWSSP
>NC_015169.1|WP_013623058.1|200662_202114_-|arginine-ornithine-antiporter
MTQHYSSEVPQAAEAPRLGLPALTALVVGSTIGGGIFALPTNVAVSAAPGPMLVGWAISAVGMLALVLVFQMLANRRPDLNTGIYAYAKAGFGNFMGFSSAWGYWISAFIGTVSYFVLMGSTIGQFVPAFGQGNTAVAIGFASALLWGIHLLVSRGIRTAASLNVITTVGKVVPLILFVILSVLAFRFDVFTADFWGKASPDLGSTLDQIKAMMMVTVWVFIGIEGASTYSSRAARRSDIGKGTVLGFLLTLFLLVSVNVLSMGIMSQQELAGLQDPSVAYVLEAVVGPWGAWLIRIGLLISLLGAMLAWTLLCTEILYAAAKDKEMPRFLARENAHGVPTGALLTTNLTVQLFLLITYFNDSTYLTLLYLASATILLPYLFSAGYGLMVASRDRYASTGERTRDLLTAGLAVLYALWLLYAAGPQYLLLSSLLYAPGALLFVKARREQGLQVFKPWELGLLALLTLAALYAAYGLKSGFLTL
>NC_015169.1|WP_013623059.1|203107_203962_+|isochorismatase-family-protein
MSNHREIYSQTESGGIQLAGGVDRWQLHEDYVHLAPHRSAAELLRFEAELLPFVDRPAQQALVIIDMQNDFLEPGGWTDASGLDYRRCREALPGVKRALEIARERDLWVVWVYWSNRPDLRNLGAPTLYSFKHRPSQKGIGEQLEHGPVLTQGSWGASMPGELQALMSEDDIHIEKVRMNGFFGTHLDQVLRTQGIETLLFAGVNIDQCVTSTMEEAYFRDYNVVLLEDACATSSPDYCREAVVFNTRNCWGFSMTTEQLAAAAPWTPDAPNQNGADQDGAAQE
>NC_015169.1|WP_148231968.1|204024_204885_-|alpha/beta-fold-hydrolase
MEQAVARQPISIQALRAREYPGSPLTTERTLERGAGYSRSVVSYRSDGLKIYALLTVPDGSPPAGGWPAIVFNHGYIPPDKYRTTERYVAYQDAFARAGFVTLKSDYRGHGDSEGEADGGYNDPGYTVDVLNAAASLKKDGRVNPARLGLWGHSMGGQLSLRAMLVDRDLKAASLWAGVVADYAVLQTEWHAPEGAQRQLDSLNRQFLRGLSPNAYLTELNGRPIQLHHGTADKDVPYSFQVALANDLRAAGQGVEAYRYEGDDHNLSGNLGLALRRSVQFFQRNL
>NC_015169.1|WP_013623061.1|205319_206138_+|hypothetical-protein
MNTANSRPALALARTLDLSVPSNQLAAGGALAGLLLGRLSGQSWAGSLRTGAGAFAAWATARELDPDHAQSAAAALAAELLLGLADSPESDLAALEELLAAFLALGSLRLLSATVGVAPTLPEQLALGGGALAAGTTNHKAAALVPGAALLLSHTRGDDLGPQEPWTGVGALVAGLLPTLLAASERDSLPARLAAMAALVVAPAAVNIEEVSARNDLDTAQIAQERVKSSRLLSTGAVALGLIAGGSRGLRPLSAACAGVGLWMLAGRAGTK
>NC_015169.1|WP_013623062.1|206216_207470_+|SGNH/GDSL-hydrolase-family-protein
MTRPAHPSVRRGRFPLAGALLLALFSAACFAQDGDKPADTAPAAQVASAAATQAAPPSFPDDPSVPVTAAQLPAQPAQPRASQPTPRMAYVALGDSLTAGMQAAGLTAAGQYAAYPAVVARMTDVPFGIPATRRGCPAPMGGGLGEGACVRVSSDLRGSNFAVPGARVQDLYQKRGVGSTDDLTRRMYGLILGPQLTQVEAALKSRPDHLTLWIGANDAMIGVTQGDPALVTPPAEFEQHYRRVLEALKPAGARTLLLTVPDVTRLPLMSPGRVLFEKGVADANCQDSENRLPLTAFLLGRKLSCDVPEALTPAETAQIQATVQAYNDAILRLAAEFGHDVMAVQPLMDQLDFHTALDENSLEPFGPDMSADGVHLSSAAQRKLGYAVVQHVHQHWNIGLPEAARSELAAAGMTVAD
>NC_015169.1|WP_013623063.1|207503_208274_-|DUF554-domain-containing-protein
MLTALSGTLANVAAVLLGGLAGLLLGGRLPEQVQRTLLQALALVTLFIGMDMAWALRELAFGPVPGVVVGLVAMVLGAVAGELLGIEDALGRMGERVQRRLRGGGRFTEGFVAATLLFCVGPMTIIGGLQNGLTGDPTTYLLKAGLDLVAATALAGVYGSGVLASALSVLVIQGGIALGALALAGGLLSGLDPASLRTHPAMLTLTGTGGLVLLGIGWNLMLGGLDLGERRVRVGSFLPALLLGPLLAWALGLLWK
>NC_015169.1|WP_013623064.1|208384_209362_+|serine-hydrolase
MFRRSSLSFLARQAADLSGASPAALERALRPLAQAPGGLGLGLQAGGHILTGGVGGLDPAAPHEIASVTKPFTAAVLGQLAAAGQLDAQAPLADLGGPFAGLPASVTPYALATHTAGLPAHPLRAGLTVLLDPYAPYSLSEGAALASARRWAAAGQAGRFGYSNLGAGVLALALAAAGGAPFPSLLARTVTGPLGLESTGFPAAPPPRATDFGTLAGAGGLWATAGDLLRFGGAHLNGQLAPAWTLTVTPRGRPTGTDEIAPGWFVTGGVWWHDGVARQSRAGLAFCPDSGRVAALLVGGPPGRFSRGAVRQALLALLGFPTHSR
>NC_015169.1|WP_013623065.1|209345_212516_-|YhgE/Pip-domain-containing-protein
MSLQQFARDFRHLTYAERSMWRWPMMWLSAAAILAVPSLYASINLASSLDPYGNLQALPVGVVNLDQGTERDGKNINMGREVMDDFRKDPPFDLTVYPSEAAARDAVRRGDIYFALTIPADFSRKAVAGDSSEHGLLRFYVAEGSNYFASRVADSFANRLSDELNKTLGETRWEAVQASLKDVQNGFGDIKDATSRLADGASDLKAGAGRLNDGAGDLKGGLDRAADGSHRLAEGAGQVSDGVQALTGGTGRLKEGIGQLNAAIPTPEKLKPLREGAAALSQGNAQLATGLGQLSTGAGQLAAGTGRLKEGADRVAAGNKQLAEQLPQLQSGLGELSTGAGQLAAGTGRLKEGADRVAAGNKQLAEQLPQLQSGLGELSTGAGQLAAGTGRLKEGADRVAAGNKQLAEQLPQLQSGLGELSTGAGQLAAGTGRLKEGADRVAAGNKQLAEQLPQLETGVGQVVTGVDALNTGAAELATGLTRLNEGVRNQPLLPGQLKSGVSELNQGSQRLHSGTNDLLQALPRLQQGASAAATGAQQLAEGAGQLSSGADELNAGAQRLAEGAKAAQTGAGQAVTGAQQLAEGAGQLSSGADELNAGAQRLAEGAKAAQTGSQQAVTGAQQLAEGAGQLSSGAGELNTGAQRLAEGTRAAQAGAGRAAAGAQQLAAGSAQLSSGAGELNTGAQTLAARSGEAAAGAARLANGAGQVQGGVNDLADGVEKIGAGVGTINRQLPAQADLDRLSSGAQTLAGSSAELSSGLDRLDEGAGDLAQGTSDLLDGAGQLSDGLNELNSKIPAETAELGGDPSGLSRSVMAQTEKFAAVANNGTGFAPYFMALSLWVGAVLTTFIFPFQQLPYSGRRTGQAARVLRKFLVPALLVVLQAVLMVFAVQALGVQYLHPVQVIATSALASLTFFSLILALILLFGSVGRFIALVLLILQLASSGGSYPVELAPPLFQAIHNWVPVTQAVGALRHAIAGAYEGQYLKFMLFLLSMLAVSGVLAMVARRRWELVDDVDFRPLIVSPLASGHVHEDDLERRIREIRDARAARAGLSESE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_015169_1	1.1\|197349\|37\|NC_015169\|CRISPRCasFinder,CRT	197349-197385	37	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	197349-197385	0	1.0
NC_015169_1	1.2\|197423\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197423-197458	36	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	197423-197458	0	1.0
NC_015169_1	1.3\|197496\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197496-197531	36	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	197496-197531	0	1.0
NC_015169_1	1.4\|197569\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197569-197604	36	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	197569-197604	0	1.0
NC_015169_1	1.5\|197642\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197642-197677	36	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	197642-197677	0	1.0
NC_015169_1	1.6\|197715\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197715-197747	33	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	197715-197747	0	1.0
NC_015169_1	1.7\|197785\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197785-197817	33	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	197785-197817	0	1.0
NC_015169_1	1.8\|197855\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197855-197890	36	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	197855-197890	0	1.0
NC_015169_1	1.9\|197928\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197928-197963	36	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	197928-197963	0	1.0
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	198001-198035	0	1.0
NC_015169_1	1.11\|198073\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198073-198105	33	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	198073-198105	0	1.0
NC_015169_1	1.12\|198143\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198143-198175	33	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	198143-198175	0	1.0
NC_015169_1	1.13\|198213\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198213-198247	35	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	198213-198247	0	1.0
NC_015169_1	1.14\|198285\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198285-198319	35	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	198285-198319	0	1.0
NC_015169_1	1.15\|198357\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198357-198391	35	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	198357-198391	0	1.0
NC_015169_1	1.16\|198429\|34\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198429-198462	34	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	198429-198462	0	1.0
NC_015169_1	1.17\|198500\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198500-198535	36	NC_015169	Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence	198500-198535	0	1.0
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	1042390-1042424	6	0.829
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NC_018683	Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence	552060-552094	7	0.8
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP026526	Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence	501384-501418	7	0.8
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	146904-146938	7	0.8
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP009145	Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence	1248754-1248788	7	0.8
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP021830	Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence	842719-842753	7	0.8
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP021824	Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence	1252304-1252338	7	0.8
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP021809	Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence	73353-73387	7	0.8
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP034185	Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence	394573-394607	7	0.8
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP015738	Shinella sp. HZN7 plasmid pShin-02, complete sequence	370251-370285	7	0.8
NC_015169_1	1.11\|198073\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198073-198105	33	KC900378	Pseudomonas phage LKA5, complete genome	5306-5338	7	0.788
NC_015169_1	1.12\|198143\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198143-198175	33	NZ_CP029333	Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence	52448-52480	7	0.788
NC_015169_1	1.12\|198143\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198143-198175	33	NC_022654	Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence	141856-141888	7	0.788
NC_015169_1	1.6\|197715\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197715-197747	33	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	506354-506386	8	0.758
NC_015169_1	1.8\|197855\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197855-197890	36	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	882497-882532	8	0.778
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	537273-537307	8	0.771
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP021819	Sinorhizobium meliloti strain M162 plasmid psymA, complete sequence	283048-283082	8	0.771
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	249870-249904	8	0.771
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	575332-575366	8	0.771
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP021813	Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence	96891-96925	8	0.771
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP054602	Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed3, complete sequence	119081-119115	8	0.771
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	473170-473204	8	0.771
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP008890	Dermacoccus nishinomiyaensis strain M25 plasmid unnamed, complete sequence	9895-9929	8	0.771
NC_015169_1	1.15\|198357\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198357-198391	35	NZ_CP029834	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence	191157-191191	8	0.771
NC_015169_1	1.15\|198357\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198357-198391	35	NZ_CP007795	Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence	338783-338817	8	0.771
NC_015169_1	1.16\|198429\|34\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198429-198462	34	NC_048732	Klebsiella phage Seifer, complete genome	23465-23498	8	0.765
NC_015169_1	1.1\|197349\|37\|NC_015169\|CRISPRCasFinder,CRT	197349-197385	37	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	945654-945690	9	0.757
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	407461-407495	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP029831	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence	358964-358998	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP010380	Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence	61807-61841	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP026171	Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence	29426-29460	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	CP009869	Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence	11577-11611	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP042479	Citrobacter freundii strain C50 plasmid pC50_001, complete sequence	51033-51067	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP040760	Paracoccus sp. 2251 plasmid unnamed6, complete sequence	23811-23845	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP032179	Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence	26426-26460	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP029142	Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence	216430-216464	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP031135	Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence	8842-8876	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP010862	Marinovum algicola DG 898 plasmid pMaD7	9730-9764	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP044111	Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2	343399-343433	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP043441	Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence	1418518-1418552	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NC_009468	Acidiphilium cryptum JF-5 plasmid pACRY02, complete sequence	147874-147908	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP026242	Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence	208987-209021	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP009883	Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence	45697-45731	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP026196	Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence	180450-180484	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_AP021845	Azospira sp. I09 plasmid pAZI09, complete sequence	2542-2576	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NC_007765	Rhizobium etli CFN 42 plasmid p42e, complete sequence	66273-66307	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP020909	Rhizobium etli strain NXC12 plasmid pRetNXC12c, complete sequence	66111-66145	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP026208	Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence	89121-89155	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP022191	Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence	166375-166409	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NC_021908	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1d, complete sequence	66099-66133	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP026391	Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence	47846-47880	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_AP014803	Rhodovulum sulfidophilum plasmid Plasmid3 DNA, complete genome, strain: DSM 2351	9727-9761	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP011635	Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence	49709-49743	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP013115	Shewanella xiamenensis strain T17 plasmid pSx1, complete sequence	211496-211530	9	0.743
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NC_015178	Acidiphilium multivorum AIU301 plasmid pACMV1, complete sequence	3943-3977	9	0.743
NC_015169_1	1.12\|198143\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198143-198175	33	NZ_CP007144	Hymenobacter swuensis DY53 plasmid pHsw1, complete sequence	193515-193547	9	0.727
NC_015169_1	1.12\|198143\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198143-198175	33	NC_007765	Rhizobium etli CFN 42 plasmid p42e, complete sequence	302216-302248	9	0.727
NC_015169_1	1.12\|198143\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198143-198175	33	NZ_CP020909	Rhizobium etli strain NXC12 plasmid pRetNXC12c, complete sequence	302652-302684	9	0.727
NC_015169_1	1.12\|198143\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198143-198175	33	NZ_CP040764	Paracoccus sp. 2251 plasmid unnamed3, complete sequence	118291-118323	9	0.727
NC_015169_1	1.12\|198143\|33\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198143-198175	33	NC_021908	Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1d, complete sequence	308654-308686	9	0.727
NC_015169_1	1.15\|198357\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198357-198391	35	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	322957-322991	9	0.743
NC_015169_1	1.15\|198357\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198357-198391	35	NZ_CP032323	Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence	768459-768493	9	0.743
NC_015169_1	1.8\|197855\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197855-197890	36	NZ_CP017321	Xanthomonas campestris pv. campestris str. CN18 plasmid unnamed1, complete sequence	9778-9813	10	0.722
NC_015169_1	1.8\|197855\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	197855-197890	36	NZ_CP017320	Xanthomonas campestris pv. campestris str. CN18 plasmid unnamed2, complete sequence	2021-2056	10	0.722
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	1422307-1422341	10	0.714
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_AP018666	Sphingobium amiense strain DSM 16289 plasmid pSAMIE_3, complete sequence	119975-120009	10	0.714
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP054841	Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence	240983-241017	10	0.714
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP020539	Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence	662334-662368	10	0.714
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP023451	Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p2, complete sequence	135171-135205	10	0.714
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_AP017656	Sphingobium cloacae strain JCM 10874 plasmid pSCLO_2, complete sequence	137881-137915	10	0.714
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP053022	Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence	251359-251393	10	0.714
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP040763	Paracoccus sp. 2251 plasmid unnamed4, complete sequence	235936-235970	10	0.714
NC_015169_1	1.10\|198001\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198001-198035	35	NZ_CP054621	Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence	383206-383240	10	0.714
NC_015169_1	1.15\|198357\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198357-198391	35	NC_016110	Streptomyces pratensis ATCC 33331 plasmid pSFLA01, complete sequence	181235-181269	10	0.714
NC_015169_1	1.15\|198357\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198357-198391	35	NZ_CP018229	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence	597190-597224	10	0.714
NC_015169_1	1.15\|198357\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198357-198391	35	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	337815-337849	10	0.714
NC_015169_1	1.15\|198357\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198357-198391	35	NZ_CP050092	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence	469934-469968	10	0.714
NC_015169_1	1.15\|198357\|35\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198357-198391	35	NC_012848	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132501, complete sequence	146126-146160	10	0.714
NC_015169_1	1.17\|198500\|36\|NC_015169\|CRISPRCasFinder,CRT,PILER-CR	198500-198535	36	NC_018532	Arthrobacter sp. Rue61a plasmid p232, complete sequence	117528-117563	10	0.722

1. spacer 1.1|197349|37|NC_015169|CRISPRCasFinder,CRT matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

ctgctgaccagcggcgaggcgctgaccccgcaggaaa	CRISPR spacer
ctgctgaccagcggcgaggcgctgaccccgcaggaaa	Protospacer
*************************************

2. spacer 1.2|197423|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

ggttttgtgcgggcctattcgccaagcatcattcat	CRISPR spacer
ggttttgtgcgggcctattcgccaagcatcattcat	Protospacer
************************************

3. spacer 1.3|197496|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

acgctgattccaggcacagataaggtctacatccct	CRISPR spacer
acgctgattccaggcacagataaggtctacatccct	Protospacer
************************************

4. spacer 1.4|197569|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

aagatggtctgatatataaaggattttagagaaggt	CRISPR spacer
aagatggtctgatatataaaggattttagagaaggt	Protospacer
************************************

5. spacer 1.5|197642|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

gacagcgagagtcttccggccgcccccgtacggccg	CRISPR spacer
gacagcgagagtcttccggccgcccccgtacggccg	Protospacer
************************************

6. spacer 1.6|197715|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

gcgggcgaagagcaggccgaccagctctacaac	CRISPR spacer
gcgggcgaagagcaggccgaccagctctacaac	Protospacer
*********************************

7. spacer 1.7|197785|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

cgccgcaggggcagaagaaggagcatgtaccca	CRISPR spacer
cgccgcaggggcagaagaaggagcatgtaccca	Protospacer
*********************************

8. spacer 1.8|197855|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

gcccgtgtctggctcaggcggcggcgcagcacttcg	CRISPR spacer
gcccgtgtctggctcaggcggcggcgcagcacttcg	Protospacer
************************************

9. spacer 1.9|197928|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

gcggatttttccgccgacctgctgaaactgaaaaac	CRISPR spacer
gcggatttttccgccgacctgctgaaactgaaaaac	Protospacer
************************************

10. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cagacccgcgccagcagcgccgccagcgcggccgc	Protospacer
***********************************

11. spacer 1.11|198073|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

ttcaagagtgaggcggctggcccaacgaggcat	CRISPR spacer
ttcaagagtgaggcggctggcccaacgaggcat	Protospacer
*********************************

12. spacer 1.12|198143|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

tttgacgtacggcttgccggtgggcaccgccag	CRISPR spacer
tttgacgtacggcttgccggtgggcaccgccag	Protospacer
*********************************

13. spacer 1.13|198213|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

caagattgagagcgcacgcatagaaaacccgttta	CRISPR spacer
caagattgagagcgcacgcatagaaaacccgttta	Protospacer
***********************************

14. spacer 1.14|198285|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

gctattcattcagcccgaagtgaggtttgactcgt	CRISPR spacer
gctattcattcagcccgaagtgaggtttgactcgt	Protospacer
***********************************

15. spacer 1.15|198357|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

atcaccggcagggcgggcggggcggccgcagagcg	CRISPR spacer
atcaccggcagggcgggcggggcggccgcagagcg	Protospacer
***********************************

16. spacer 1.16|198429|34|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

cggcccggagtgctgccacatgctgatcgcggag	CRISPR spacer
cggcccggagtgctgccacatgctgatcgcggag	Protospacer
**********************************

17. spacer 1.17|198500|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015169 (Deinococcus proteolyticus MRP plasmid pDEIPR01, complete sequence) position: , mismatch: 0, identity: 1.0

gtaggtgagggtgtactcacgctcgaacaccttttt	CRISPR spacer
gtaggtgagggtgtactcacgctcgaacaccttttt	Protospacer
************************************

18. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 6, identity: 0.829

cagacccg-cgccagcagcgccgccagcgcggccgc	CRISPR spacer
-aggctggtcgccagcagcgccgccagcggggcggc	Protospacer
 **.*. * ******************** *** **

19. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_018683 (Sinorhizobium meliloti Rm41 plasmid pSYMA, complete sequence) position: , mismatch: 7, identity: 0.8

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgcggcagcgccagcagcggcgccagcgcggtcgc	Protospacer
*. . * ************ ***********.***

20. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026526 (Sinorhizobium meliloti strain AK21 plasmid pSymA, complete sequence) position: , mismatch: 7, identity: 0.8

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgcggcagcgccagcagcggcgccagcgcggtcgc	Protospacer
*. . * ************ ***********.***

21. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022542 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence) position: , mismatch: 7, identity: 0.8

cagacccgcgccagcagcgccgccagcgcggccgc-----	CRISPR spacer
cagacccgccccagcagcgccgcca-----gtcgcaaaaa	Protospacer
********* ***************     *.***

22. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009145 (Sinorhizobium meliloti strain RMO17 plasmid pSymA, complete sequence) position: , mismatch: 7, identity: 0.8

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgcggcagcgccagcagcggcgccagcgcggtcgc	Protospacer
*. . * ************ ***********.***

23. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021830 (Sinorhizobium meliloti strain HM006 plasmid psymA, complete sequence) position: , mismatch: 7, identity: 0.8

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgcggcagcgccagcagcggcgccagcgcggtcgc	Protospacer
*. . * ************ ***********.***

24. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021824 (Sinorhizobium meliloti strain KH46 plasmid psymA, complete sequence) position: , mismatch: 7, identity: 0.8

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgcggcagcgccagcagcggcgccagcgcggtcgc	Protospacer
*. . * ************ ***********.***

25. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021809 (Sinorhizobium meliloti strain Rm41 plasmid psymA, complete sequence) position: , mismatch: 7, identity: 0.8

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgcggcagcgccagcagcggcgccagcgcggtcgc	Protospacer
*. . * ************ ***********.***

26. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034185 (Deinococcus sp. S14-83 strain S14-83T plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.8

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cacaccagcgccagcagcgccgccagccccatccc	Protospacer
** *** ******************** * ..* *

27. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015738 (Shinella sp. HZN7 plasmid pShin-02, complete sequence) position: , mismatch: 7, identity: 0.8

cagacccgcgccagcagcgccgccagcg-cggccgc	CRISPR spacer
cgatcccgccccagccgcgccgccagcgccggctg-	Protospacer
*.. ***** ***** ************ ****.*

28. spacer 1.11|198073|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to KC900378 (Pseudomonas phage LKA5, complete genome) position: , mismatch: 7, identity: 0.788

ttcaagagtgaggcggctggcccaacgaggcat	CRISPR spacer
ctccagcaggatgcggctggcccaacgcggcat	Protospacer
.** ** . ** *************** *****

29. spacer 1.12|198143|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029333 (Mycobacterium avium subsp. hominissuis strain MAC109 plasmid pMAC109a, complete sequence) position: , mismatch: 7, identity: 0.788

tttgacgta---cggcttgccggtgggcaccgccag	CRISPR spacer
---gaagtggatcggcttgccgatggccaccgccag	Protospacer
   ** **.   **********.*** *********

30. spacer 1.12|198143|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_022654 (Mycobacterium kansasii ATCC 12478 plasmid pMK12478, complete sequence) position: , mismatch: 7, identity: 0.788

tttgacgta---cggcttgccggtgggcaccgccag	CRISPR spacer
---gaagtggatcggcttgccgatggccaccgccag	Protospacer
   ** **.   **********.*** *********

31. spacer 1.6|197715|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.758

gcgggcgaagagcaggccgaccagctctacaac	CRISPR spacer
ccaggcgaagagccagccgaccagctcagtgac	Protospacer
 *.********** .************ ...**

32. spacer 1.8|197855|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 8, identity: 0.778

gcccgtgtctggctcaggcggcggcgcagcacttcg	CRISPR spacer
ggctccgccgggctcaggcggcggcacagcgcttcg	Protospacer
* *. .*.* ***************.****.*****

33. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.771

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
tgggtccaggccagcagcgccgcgatcgcggccgc	Protospacer
..*..**. ************** * *********

34. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021819 (Sinorhizobium meliloti strain M162 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.771

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgcggcagggccagcagcggcgccagcgcggtcgc	Protospacer
*. . * * ********** ***********.***

35. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.771

cagacccg----cgccagcagcgccgccagcgcggccgc	CRISPR spacer
----cccggcaccgccagcagcggcgccagcgccgccag	Protospacer
    ****    *********** ********* ***.

36. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 8, identity: 0.771

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
ccgcgcgccgccagcagcgccgccagcttggccgg	Protospacer
* *  *  ******************* .*****

37. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021813 (Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.771

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgcggcagggccagcagcggcgccagcgcggtcgc	Protospacer
*. . * * ********** ***********.***

38. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054602 (Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.771

-cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
ccaagcgcat-ccagcagcgccgccagcgtggacgc	Protospacer
 **..* *.. ******************.** ***

39. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.771

--cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
ctcggact--ttccagtagcgccgcccgcgcggccgc	Protospacer
  *.***.  . ****.********* **********

40. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP008890 (Dermacoccus nishinomiyaensis strain M25 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.771

cagacccgcgccagcagcgccgccagcgcggccgc-	CRISPR spacer
ataccccgcgcctgcagcgccgccaccgc-accgcg	Protospacer
  . ******** ************ *** .****

41. spacer 1.15|198357|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029834 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.771

atcaccggcagggcgggcggggcggccgcagagcg	CRISPR spacer
cgcaccggcggggcgggcggggcggcctcggtcgg	Protospacer
  *******.***************** *.*   *

42. spacer 1.15|198357|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007795 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p2, complete sequence) position: , mismatch: 8, identity: 0.771

atcaccggcagggcgggcggggcggccgcagagcg	CRISPR spacer
atcaccggcagggcgggcgggttggcccaggcggt	Protospacer
********************* .****  .* *

43. spacer 1.16|198429|34|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_048732 (Klebsiella phage Seifer, complete genome) position: , mismatch: 8, identity: 0.765

cggcccggagtgctgccacatgctgatcgcggag	CRISPR spacer
cggcccggactgctgccacctgctgacggtacat	Protospacer
********* ********* ******. *.. *

44. spacer 1.1|197349|37|NC_015169|CRISPRCasFinder,CRT matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 9, identity: 0.757

ctgctgaccagcggcgaggcgctgaccccgcaggaaa	CRISPR spacer
ttgctgaccagcggcgacgcgcagaccatgccgccat	Protospacer
.**************** **** **** .** *  *

45. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
tcgttgcgcgccagcagcgcctccagcgcggcgat	Protospacer
. * . *************** ********** ..

46. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029831 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed7, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
ttgacccgcgccagctccgccgccagcgcatcgtg	Protospacer
. *************  ************. *

47. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010380 (Enterobacter hormaechei subsp. hormaechei strain 34983 plasmid p34983-328.905kb, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

48. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026171 (Leclercia sp. LSNIH1 plasmid pLEC-1cb1, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

49. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to CP009869 (Pantoea sp. PSNIH2 plasmid pPSP-75c, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

50. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042479 (Citrobacter freundii strain C50 plasmid pC50_001, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

51. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040760 (Paracoccus sp. 2251 plasmid unnamed6, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
gacgcgcccgacagcagcgcctccagcgcggccta	Protospacer
 * .* * ** ********** ***********

52. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032179 (Citrobacter freundii strain AR_0116 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

53. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029142 (Klebsiella michiganensis strain AR375 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

54. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP031135 (Escherichia coli strain CFSAN064035 plasmid pGMI17-003_1, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

55. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010862 (Marinovum algicola DG 898 plasmid pMaD7) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
atcgcccagaccagaagcgccgccagcgccgccgc	Protospacer
   .***. .**** ************** *****

56. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP044111 (Klebsiella michiganensis strain FDAARGOS_647 plasmid unnamed2) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

57. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP043441 (Cupriavidus campinensis strain MJ1 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
aaacggcggtccagcagcggcgccagcgtggccgc	Protospacer
 *.   **  ********* ********.******

58. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_009468 (Acidiphilium cryptum JF-5 plasmid pACRY02, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
ctcgccggcgcccgcagcgccgccagcgcctatgc	Protospacer
*  .** ***** ****************   .**

59. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026242 (Citrobacter freundii complex sp. CFNIH9 plasmid pCFR-eb27, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

60. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009883 (Pantoea sp. PSNIH1 plasmid pPSP-a3e, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

61. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026196 (Enterobacteriaceae bacterium ENNIH1 plasmid pENT-1f0b, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

62. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP021845 (Azospira sp. I09 plasmid pAZI09, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

63. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_007765 (Rhizobium etli CFN 42 plasmid p42e, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
gcgtccctcgccagccgcgccgccagcgcctcgcc	Protospacer
  * *** ******* *************  *  *

64. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020909 (Rhizobium etli strain NXC12 plasmid pRetNXC12c, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
gcgtccctcgccagccgcgccgccagcgcctcgcc	Protospacer
  * *** ******* *************  *  *

65. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026208 (Escherichia coli strain ECONIH5 plasmid pECO-109b, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

66. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022191 (Yangia pacifica strain YSBP01 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cagagcagcgccagcagcgccgccatgaggtttgc	Protospacer
**** * ******************  . * ..**

67. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_021908 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1d, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
gcgtccctcgccagccgcgccgccagcgcctcgcc	Protospacer
  * *** ******* *************  *  *

68. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026391 (Leclercia sp. LSNIH3 plasmid pLEC-7c0d, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

69. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP014803 (Rhodovulum sulfidophilum plasmid Plasmid3 DNA, complete genome, strain: DSM 2351) position: , mismatch: 9, identity: 0.743

--cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
agcgga--tagaccagcagcgccgccagcgcaggcgc	Protospacer
  *.**  .. .*******************.* ***

70. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011635 (Klebsiella oxytoca strain CAV1374 plasmid pKPC_CAV1374, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

71. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013115 (Shewanella xiamenensis strain T17 plasmid pSx1, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
cgtctcagcgccagcagcgccgcccgcgctgctgg	Protospacer
*.  .* ***************** **** **.*

72. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_015178 (Acidiphilium multivorum AIU301 plasmid pACMV1, complete sequence) position: , mismatch: 9, identity: 0.743

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
ctcgccggcgcccgcagcgccgccagcgcctatgc	Protospacer
*  .** ***** ****************   .**

73. spacer 1.12|198143|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007144 (Hymenobacter swuensis DY53 plasmid pHsw1, complete sequence) position: , mismatch: 9, identity: 0.727

tttgacgtacggcttgccggtgggcaccgccag	CRISPR spacer
caaggcatatggcttgccggtggccaccgcctc	Protospacer
.  *.*.**.************* *******

74. spacer 1.12|198143|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_007765 (Rhizobium etli CFN 42 plasmid p42e, complete sequence) position: , mismatch: 9, identity: 0.727

tttgacgtacggcttgccggtgggcaccgccag	CRISPR spacer
ggagagaaacggcttgccggtgggaagcgccat	Protospacer
   ** . **************** * *****

75. spacer 1.12|198143|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020909 (Rhizobium etli strain NXC12 plasmid pRetNXC12c, complete sequence) position: , mismatch: 9, identity: 0.727

tttgacgtacggcttgccggtgggcaccgccag	CRISPR spacer
ggagagaaacggcttgccggtgggaagcgccat	Protospacer
   ** . **************** * *****

76. spacer 1.12|198143|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040764 (Paracoccus sp. 2251 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.727

tttgacgtacggcttgccggtgggcaccgccag	CRISPR spacer
cgtgggcgaccgcctgccggtgggcaccgccac	Protospacer
. **.   ** **.******************

77. spacer 1.12|198143|33|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_021908 (Rhizobium etli bv. mimosae str. Mim1 plasmid pRetMIM1d, complete sequence) position: , mismatch: 9, identity: 0.727

tttgacgtacggcttgccggtgggcaccgccag	CRISPR spacer
ggagagaaacggcttgccggtgggaagcgccat	Protospacer
   ** . **************** * *****

78. spacer 1.15|198357|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 9, identity: 0.743

atcaccggcagggcgggcggggcggccgcagagcg	CRISPR spacer
acgcccggcagggcggacagggcggccgcagcctc	Protospacer
*.  ************.*.************  .

79. spacer 1.15|198357|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032323 (Azospirillum brasilense strain MTCC4035 plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.743

atcaccggcagggcgggcggggcggccgcagagcg	CRISPR spacer
accaccggcagggcgggcgggttggcccaggcggt	Protospacer
*.******************* .****  .* *

80. spacer 1.8|197855|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017321 (Xanthomonas campestris pv. campestris str. CN18 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.722

gcccgtgtctggctcaggcggcggcgcagcacttcg	CRISPR spacer
aaaccgatctggctcggtcggcggcgcagcactacc	Protospacer
.  *  .********.* *************** *

81. spacer 1.8|197855|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP017320 (Xanthomonas campestris pv. campestris str. CN18 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.722

gcccgtgtctggctcaggcggcggcgcagcacttcg	CRISPR spacer
aaaccgatctggctcggtcggcggcgcagcactacc	Protospacer
.  *  .********.* *************** *

82. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 10, identity: 0.714

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
atggcccgcgccagcagcaccgccggcgcattcca	Protospacer
  *.**************.*****.****. .*

83. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP018666 (Sphingobium amiense strain DSM 16289 plasmid pSAMIE_3, complete sequence) position: , mismatch: 10, identity: 0.714

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
gcagcccgcgccagcagcaccgcgagcgcgcagga	Protospacer
  ..**************.**** ******   *

84. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054841 (Acidovorax sp. 16-35-5 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
tggcggtcggccagcagcgccggcagcgcgggcgc	Protospacer
..*   .  ************* ******** ***

85. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020539 (Sphingobium herbicidovorans strain MH plasmid pMSHV, complete sequence) position: , mismatch: 10, identity: 0.714

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
gcagcccgcgccagcagcaccgcgagcgcgcagga	Protospacer
  ..**************.**** ******   *

86. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023451 (Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.714

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
gcagcccgcgccagcagcaccgcgagcgcgcagga	Protospacer
  ..**************.**** ******   *

87. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP017656 (Sphingobium cloacae strain JCM 10874 plasmid pSCLO_2, complete sequence) position: , mismatch: 10, identity: 0.714

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
gcagcccgcgccagcagcaccgcgagcgcgcagga	Protospacer
  ..**************.**** ******   *

88. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053022 (Sphingobium yanoikuyae strain YC-XJ2 plasmid p-A-Sy, complete sequence) position: , mismatch: 10, identity: 0.714

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
gcagcccgcgccagcagcaccgcgagcgcgcagga	Protospacer
  ..**************.**** ******   *

89. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040763 (Paracoccus sp. 2251 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.714

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
gcaagccgcgcgatcagcgccgccagcgcgtcgaa	Protospacer
  .* ****** * **************** * .

90. spacer 1.10|198001|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054621 (Azospirillum oryzae strain KACC 14407 plasmid unnamed6, complete sequence) position: , mismatch: 10, identity: 0.714

cagacccgcgccagcagcgccgccagcgcggccgc	CRISPR spacer
atggcccgcgccagcagcaccgccggcgcattcca	Protospacer
  *.**************.*****.****. .*

91. spacer 1.15|198357|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_016110 (Streptomyces pratensis ATCC 33331 plasmid pSFLA01, complete sequence) position: , mismatch: 10, identity: 0.714

atcaccggcagggcgggcggggcggccgcagagcg	CRISPR spacer
ggtaccggcggggcgggcggggaggccgcccgccc	Protospacer
. .******.************ ******  . *

92. spacer 1.15|198357|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP018229 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

atcaccggcagggcgggcggggcggccgcagagcg	CRISPR spacer
cccatcggcagggcgggcgtggcggcccacttccg	Protospacer
 .**.************** *******      **

93. spacer 1.15|198357|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 10, identity: 0.714

atcaccggcagggcgggcggggcggccgcagagcg	CRISPR spacer
cccatcggcagggcgggcgtggcggcccacttccg	Protospacer
 .**.************** *******      **

94. spacer 1.15|198357|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050092 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b6, complete sequence) position: , mismatch: 10, identity: 0.714

atcaccggcagggcgggcggggcggccgcagagcg	CRISPR spacer
cccatcggcagggcgggcgtggcggcccacttccg	Protospacer
 .**.************** *******      **

95. spacer 1.15|198357|35|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_012848 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132501, complete sequence) position: , mismatch: 10, identity: 0.714

atcaccggcagggcgggcggggcggccgcagagcg	CRISPR spacer
cccatcggcagggcgggcgtggcggcccacttccg	Protospacer
 .**.************** *******      **

96. spacer 1.17|198500|36|NC_015169|CRISPRCasFinder,CRT,PILER-CR matches to NC_018532 (Arthrobacter sp. Rue61a plasmid p232, complete sequence) position: , mismatch: 10, identity: 0.722

gtaggtgagggtgtactcacgctcgaacaccttttt	CRISPR spacer
tgcggtgggggtgtacgcacgctcgaacacggtgcc	Protospacer
   ****.******** *************  * ..

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage