CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_014915	Geobacillus sp. Y412MC52, complete sequence	9 crisprs	cas8b1,cas7,cas5,cas3,cas4,cas1,cas2,cas6,csm6,csx1,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,RT,csa3,c2c10_CAS-V-U3,cas14j,DEDDh,DinG	2	40	12	1
NC_014916	Geobacillus sp. Y412MC52 plasmid pGYMC5201, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_014915_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014915_1

339380-341000

TypeIII

Consensus_repeat	Method
GTTTTTATCGTACCTATGAGGGATTGAAAC	PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRT

24 spacers

cas8b1,cas7,cas5,cas3,cas4,cas1,cas2,cas6,csm6,csx1

The CRISPR arrays of NC_014915_1

>merge|NC_014915|1|339380-341000|PILER-CR,CRISPRCasFinder,CRT
GTTTTTATCGTACCTATGAGGGATTGAAACCTATGAACAGTATGGAACTAAATATGTGACATGGGGAGTTTTTATCGTACCTATGAGGGATTGAAACTACTACACATGTAGTACATTGTCAACATTCTTTTGAGTTTTTATCGTACCTATGAGGGATTGAAACGCCGCAAGCCATACGCGCCAGTACATCGACTTCGCGTTTTTATCGTACCTATGAGGGATTGAAACCTCCCCTTATTGCCAGTCCGAATCAGTCGGACTGGCGTTTTTATCGTACCTATGAGGGATTGAAACTTCCACCTCTAACAGCTCGGCCGGGATGATCCAAGGCGTTTTTATCGTACCTATGAGGGATTGAAACAAAAATTTGCAAATCGTCCTGTAGAACATGTATTTACGTTTTTATCGTACCTATGAGGGATTGAAACTGCGCTAATCCTTTCGAAACGGTACCGGAGCAAATTCGTTTTTATCGTACCTATGAGGGATTGAAACGGACAACTGTTCCTTTCTCTACTCTTTCTCTCCATCGTTTTTATCGTACCTATGAGGGATTGAAACCTCTTAAAGAGTGGCGTGATGTTGACGTCCGCGTACGTTTTTATCGTACCTATGAGGGATTGAAACATGGAACGATCACGGTACATAATGATGATCGTCGCGTTTTTATCGTACCTATGAGGGATTGAAACCTTGGTATAACAATGTCATGTCGTCTGTTGGTGTTTGTTTTTATCGTACCTATGAGGGATTGAAACTTGCACCCACTATTGACCGCCTCCAAGTAGTTTTCTGTTTTTATCGTACCTATGAGGGATTGAAACGTAGTAACAAGCTGTCTAAACTTGTCAGCATAATCGTTTTTATCGTACCTATGAGGGATTGAAACACTAGCGTTCGGCAAGCTATCGAGATACCGTTTAAGTTTTTATCGTACCTATGAGGGATTGAAACTCTACGCAATATAGCGCGTCCATAGCCTTTTCGATAGGTTTTTATCGTACCTATGAGGGATTGAAACTATGACAAAATGGGTTAATATGGTGACAAAAGGAAAGTTTTTATCGTACCTATGAGGGATTGAAACCAGGGTTGAAATAATCTGTCATTGAATCGCTTTGGTCGTTTTTATCGTACCTATGAGGGATTGAAACCCCGACCCGTTTTTTATCATCGCTTCATGGAAACAGAGGTTTTTATCGTACCTATGAGGGATTGAAACATATATTAAAAGGCTAAAAATGGGCGCTCTGGGGCGCGTTTTTATCGTACCTATGAGGGATTGAAACTTTTTGAAGGTCGCGAATGTTTCTCGGAGGGGCATAACGTTTTTATCGTACCTATGAGGGATTGAAACTTTTTCTGCTCGATGTAAATATCCAAAAGCGGCGTTCGTTTTTATCGTACCTATGAGGGATTGAAACCAAGAGGCGATCGAGGACAAGGCTGAGAATATCGGGTTTTTATCGTACCTATGAGGGATTGAAACTCCAATCGCCCGCGTCGTTCCAATAGCCGCCGCTCGTTTTTATCGTACCTATGAGGGATTGAAACTCTGACCGCTGCTCCACTGATCGGTTTAATTGAGCCAGTTTTTATCGTACCTATGAGGGATGAAACC

>NC_014915|1|1|339380-340933|PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTATGAACAGTATGGAACTAAATATGTGACATGGGGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TACTACACATGTAGTACATTGTCAACATTCTTTTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCCGCAAGCCATACGCGCCAGTACATCGACTTCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTCCCCTTATTGCCAGTCCGAATCAGTCGGACTGGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCCACCTCTAACAGCTCGGCCGGGATGATCCAAGGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAAATTTGCAAATCGTCCTGTAGAACATGTATTTAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGCGCTAATCCTTTCGAAACGGTACCGGAGCAAATTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGACAACTGTTCCTTTCTCTACTCTTTCTCTCCATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTCTTAAAGAGTGGCGTGATGTTGACGTCCGCGTAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATGGAACGATCACGGTACATAATGATGATCGTCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTTGGTATAACAATGTCATGTCGTCTGTTGGTGTTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTGCACCCACTATTGACCGCCTCCAAGTAGTTTTCT
GTTTTTATCGTACCTATGAGGGATTGAAAC	GTAGTAACAAGCTGTCTAAACTTGTCAGCATAATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACTAGCGTTCGGCAAGCTATCGAGATACCGTTTAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCTACGCAATATAGCGCGTCCATAGCCTTTTCGATAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TATGACAAAATGGGTTAATATGGTGACAAAAGGAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	CAGGGTTGAAATAATCTGTCATTGAATCGCTTTGGTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCCGACCCGTTTTTTATCATCGCTTCATGGAAACAGAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATATATTAAAAGGCTAAAAATGGGCGCTCTGGGGCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTGAAGGTCGCGAATGTTTCTCGGAGGGGCATAAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTCTGCTCGATGTAAATATCCAAAAGCGGCGTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CAAGAGGCGATCGAGGACAAGGCTGAGAATATCGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCAATCGCCCGCGTCGTTCCAATAGCCGCCGCTC
GTTTTTATCGTACCTATGAGGGATTGAAAC

>NC_014915|1|1|339380-341000|CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTATGAACAGTATGGAACTAAATATGTGACATGGGGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TACTACACATGTAGTACATTGTCAACATTCTTTTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCCGCAAGCCATACGCGCCAGTACATCGACTTCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTCCCCTTATTGCCAGTCCGAATCAGTCGGACTGGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCCACCTCTAACAGCTCGGCCGGGATGATCCAAGGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAAATTTGCAAATCGTCCTGTAGAACATGTATTTAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGCGCTAATCCTTTCGAAACGGTACCGGAGCAAATTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGACAACTGTTCCTTTCTCTACTCTTTCTCTCCATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTCTTAAAGAGTGGCGTGATGTTGACGTCCGCGTAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATGGAACGATCACGGTACATAATGATGATCGTCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTTGGTATAACAATGTCATGTCGTCTGTTGGTGTTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTGCACCCACTATTGACCGCCTCCAAGTAGTTTTCT
GTTTTTATCGTACCTATGAGGGATTGAAAC	GTAGTAACAAGCTGTCTAAACTTGTCAGCATAATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACTAGCGTTCGGCAAGCTATCGAGATACCGTTTAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCTACGCAATATAGCGCGTCCATAGCCTTTTCGATAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TATGACAAAATGGGTTAATATGGTGACAAAAGGAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	CAGGGTTGAAATAATCTGTCATTGAATCGCTTTGGTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCCGACCCGTTTTTTATCATCGCTTCATGGAAACAGAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATATATTAAAAGGCTAAAAATGGGCGCTCTGGGGCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTGAAGGTCGCGAATGTTTCTCGGAGGGGCATAAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTCTGCTCGATGTAAATATCCAAAAGCGGCGTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CAAGAGGCGATCGAGGACAAGGCTGAGAATATCGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCAATCGCCCGCGTCGTTCCAATAGCCGCCGCTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCTGACCGCTGCTCCACTGATCGGTTTAATTGAGCCA
GTTTTTATCGTACCTATGAGGGATGAAACC

>NC_014915|1|1|339380-341000|CRT
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTATGAACAGTATGGAACTAAATATGTGACATGGGGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TACTACACATGTAGTACATTGTCAACATTCTTTTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCCGCAAGCCATACGCGCCAGTACATCGACTTCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTCCCCTTATTGCCAGTCCGAATCAGTCGGACTGGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCCACCTCTAACAGCTCGGCCGGGATGATCCAAGGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAAATTTGCAAATCGTCCTGTAGAACATGTATTTAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGCGCTAATCCTTTCGAAACGGTACCGGAGCAAATTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGACAACTGTTCCTTTCTCTACTCTTTCTCTCCATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTCTTAAAGAGTGGCGTGATGTTGACGTCCGCGTAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATGGAACGATCACGGTACATAATGATGATCGTCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTTGGTATAACAATGTCATGTCGTCTGTTGGTGTTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTGCACCCACTATTGACCGCCTCCAAGTAGTTTTCT
GTTTTTATCGTACCTATGAGGGATTGAAAC	GTAGTAACAAGCTGTCTAAACTTGTCAGCATAATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACTAGCGTTCGGCAAGCTATCGAGATACCGTTTAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCTACGCAATATAGCGCGTCCATAGCCTTTTCGATAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TATGACAAAATGGGTTAATATGGTGACAAAAGGAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	CAGGGTTGAAATAATCTGTCATTGAATCGCTTTGGTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCCGACCCGTTTTTTATCATCGCTTCATGGAAACAGAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATATATTAAAAGGCTAAAAATGGGCGCTCTGGGGCGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTGAAGGTCGCGAATGTTTCTCGGAGGGGCATAAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTCTGCTCGATGTAAATATCCAAAAGCGGCGTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CAAGAGGCGATCGAGGACAAGGCTGAGAATATCGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCAATCGCCCGCGTCGTTCCAATAGCCGCCGCTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCTGACCGCTGCTCCACTGATCGGTTTAATTGAGCCA
GTTTTTATCGTACCTATGAGGGATGAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014915.1\|WP_013522859.1\|331627_332824_+\|TIGR02678-family-protein	unknown	unknown	gnl\|CDD\|274254
NC_014915.1\|WP_013522858.1\|330134_331625_+\|TIGR02677-family-protein	unknown	unknown	gnl\|CDD\|131724
NC_014915.1\|WP_013522869.1\|348478_348742_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_014915.1\|WP_013522861.1\|336901_338122_+\|TIGR02679-family-protein	unknown	unknown	gnl\|CDD\|274255
NC_014915.1\|WP_013522872.1\|353886_355227_+\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl\|CDD\|378186
NC_014915.1\|WP_013522853.1\|324822_325410_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NC_014915.1\|WP_013522862.1\|338266_339181_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NC_014915.1\|WP_013522863.1\|341179_342895_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_014915.1\|WP_013522870.1\|348778_349525_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_014915.1\|WP_013522871.1\|352687_353884_+\|CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl\|CDD\|187873
NC_014915.1\|WP_013522865.1\|343868_344612_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_014915.1\|WP_013522856.1\|327885_328788_-\|substrate-binding-region-of-ABC-type-glycine-betaine-transporter	unknown	unknown	gnl\|CDD\|270246
NC_014915.1\|WP_013522864.1\|342896_343853_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_014915.1\|WP_013522867.1\|346953_347463_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_014915.1\|WP_013522868.1\|347466_348468_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_014915.1\|WP_013522857.1\|329258_329990_-\|coiled-coil-protein	unknown	unknown	gnl\|CDD\|224117
NC_014915.1\|WP_013522866.1\|344613_346944_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_014915.1\|WP_013522854.1\|325857_326487_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NC_014915.1\|WP_013522855.1\|326741_327869_-\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213262
NC_014915.1\|WP_013522860.1\|332783_336845_+\|TIGR02680-family-protein	unknown	unknown	gnl\|CDD\|274256

Protein	Function_ID	Function_description	E-value
NC_014915.1\|WP_013522859.1\|331627_332824_+\|TIGR02678-family-protein	gnl\|CDD\|274254	TIGR02678, hypothetical_protein, TIGR02678 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	1.24902e-155
NC_014915.1\|WP_013522858.1\|330134_331625_+\|TIGR02677-family-protein	gnl\|CDD\|131724	TIGR02677, conserved_hypothetical_protein, TIGR02677 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	0
NC_014915.1\|WP_013522869.1\|348478_348742_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.421e-34
NC_014915.1\|WP_013522861.1\|336901_338122_+\|TIGR02679-family-protein	gnl\|CDD\|274255	TIGR02679, conserved_hypothetical_protein, TIGR02679 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	3.05546e-140
NC_014915.1\|WP_013522872.1\|353886_355227_+\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	8.05541e-64
NC_014915.1\|WP_013522853.1\|324822_325410_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	8.27805e-41
NC_014915.1\|WP_013522862.1\|338266_339181_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.51656e-15
NC_014915.1\|WP_013522863.1\|341179_342895_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.69786e-150
NC_014915.1\|WP_013522870.1\|348778_349525_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.34584e-34
NC_014915.1\|WP_013522871.1\|352687_353884_+\|CRISPR-associated-protein	gnl\|CDD\|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	1.96696e-15
NC_014915.1\|WP_013522865.1\|343868_344612_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	3.79723e-31
NC_014915.1\|WP_013522856.1\|327885_328788_-\|substrate-binding-region-of-ABC-type-glycine-betaine-transporter	gnl\|CDD\|270246	cd13528, PBP2_osmoprotectants, Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 periplasmic-binding protein fold. This family represents the periplasmic substrate-binding component of ABC transport systems that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, bacteria and archaea accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.80829e-141
NC_014915.1\|WP_013522864.1\|342896_343853_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	4.88644e-92
NC_014915.1\|WP_013522867.1\|346953_347463_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.12896e-73
NC_014915.1\|WP_013522868.1\|347466_348468_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	1.11603e-171
NC_014915.1\|WP_013522857.1\|329258_329990_-\|coiled-coil-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	1.13488e-12
NC_014915.1\|WP_013522866.1\|344613_346944_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.07841e-46
NC_014915.1\|WP_013522854.1\|325857_326487_-\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	1.95598e-80
NC_014915.1\|WP_013522855.1\|326741_327869_-\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213262	cd03295, ABC_OpuCA_Osmoprotection, ATP-binding cassette domain of the osmoprotectant transporter. OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	3.41823e-163
NC_014915.1\|WP_013522860.1\|332783_336845_+\|TIGR02680-family-protein	gnl\|CDD\|274256	TIGR02680, conserved_hypothetical_protein, TIGR02680 family protein. Members of this protein family belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). Proteins in this family average over 1400 amino acids in length. [Hypothetical proteins, Conserved].	0

>NC_014915.1|WP_013522862.1|338266_339181_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAKQRIDHDRLFKELLSTFFEEFLLLFFPNVYEHIDVHHLSFLSEELFTDVTAGEKHRVDLLVETKVKGEDGLVIVHVEHQSYTQRTFPERMFLYFSRLFQKYRRRIVPIAIFSYDEHHDEPSSLIVQFPFLKVLDFRFLTVELRKQPWRQYIHQDNPVAAALLSKMGYNEEEKVEVKKEFLRMLVRLELDEAKQRLLFGFFETYLRLSEEEEAKLRNEVSQMETKEAKQVMELIISYEQRGMEKGIQQGMEQGLKQGMKQGRQKGIEEGKLDVVKRMLAKGYDVDTIHELTGLPVEKIERVKG
>NC_014915.1|WP_013522861.1|336901_338122_+|TIGR02679-family-protein
MSTVKEAAAFFRSEPGFKRLFVEMKRKYESLGRVGGAVSLQSFSKEEREAVAAFFGKDVVRVSLSAFEKQLGQTKFAGVGLVALLEQYFGEPLVPKKERLQAEEDERERFFARLAEEHHWFAAVRGQRFVQTAYEADRDGLEAAVRLVGAALCRLPLSSYMRLPLFAQQVASDPHAFDLSTLPGRLLLSALQATTPGQWDVTSVESVNELLQSVGLLREDILNFVTCANILAETEGGPHPVFSAASETNTALNMPLRDVLSLVSVRPARGGTVYIVENAGVFSTLLDTRAPLVSTNGQMNLATMKLLDLLAASGAKLYYSGDFDPEGLAMAERLLERYGQSVTLWRFSLDDYAAANPVVALSSERLAKLASVTSAPLQPLKEEMKRKKKAGYQEAIIGRLTGDING
>NC_014915.1|WP_013522860.1|332783_336845_+|TIGR02680-family-protein
MANPWVLHRAGLINFWYYDEQYFHFADGKLLLRGSNGAGKSVTMQSLIPVLLDGKKTPDRLDPFGSRARRMEDYLLGEKDVVNRDERTGYLFLEYKRKESDQYVTTGIGLRAKRQKSLDFWGFVLFDNRRIGYDLQLYKQEKTGEKIPLTKRELAALLGPGGTVVETQKEYMELVNKHVFRFESLEAFQELIELLIQLRSPKLSKDFKPTVIYEILESSLPPLTDDELRHLSETIENMDQAKQQLEQLERDERALKRLCDQYRLYNEYMIAEKAAEYVKAVKQAEQLAAEQHRLHDEEEQARKALDELDESIIRLRREEDVLRSREIDLAGHEVFQQAEKYEQLKAERERLQERRERHEQTIAEKERLERQHRRRLDESEARLDDLERKLEDELAQLRADAEEGAFSLHETNEDDFHRHRQKQQEFSFAAWKQEADRHIERLEELARLWRRHDDVKRRYEEASNEAGERRREMDEWRHQQRKWEELFEQEKERFEQAVLAWVEQGGIDVSETDIQAFLQQMGSLYEQYSLDDLKRPFVQAYYDAVGKKKDEKWRLEHDIRLLEEKRAEREAELRQWREQRDPEPERDEQTTAARLALEQEGIPFVPFYAAVEFVDDVPEDVRERIESALSHAGLLDALIAARDVDVDCDRVLIPKPVHMAHTLADYLRPDADAPVSAERIDEVLRSIVITDAEQEGGMTIDETGRYSLGLVRGHAPRRARAMFIGRAARERWRLENIAALEAEIAALGQEIDRLRREHQAVEAAIRALADWFVSFPSDRDVRTAFEEGQEARRQAESKEREWKRQEEKAALLAREWKQIKQQLHDESAELDLAFTLDGCEQAQLAMKSYVRHLHELEVLYRETRHTEAMIAQQRERLAALETEIDEAKGERNRLRDDEERISLEIAEMERTLAQMGADDIRAEIARIQERLAFLRQEIPRLVNERARTEQRLMRLVEEREKGAQREAFACQLAAMWGRSFADEAALGLVDLDRSRSLLEQAKEAKQRYEAVLKETRSSLLARLNTVFFQESSNLTEYRATFERLAEQKEPEWIAAAPDDEMAMKAADWREKQERHVIYLDYKGQRATPFAVLAEVERDIALQHEYMKEQDRELYEDVILKSVGRILRSRIQRAERWVSDMNKLMGGLDTSSGLVLSIQWKPKTAETEAELDTKELVRLLRIDSRLLREEDLQRVTNHFRSKIARARELLEERGQGNTLHQIIKEVLDYRKWFAFTLYYEKTNEPKRELTNHRFYQFSGGEKAMAMYIPLFAAAYSRYQEAGDDAPYIISLDEAFAGVDENNIRNLFGLVEQLGFNYIMNSQALWGDYDTVPALSICELVRPRNASFVTVIHYR
>NC_014915.1|WP_013522859.1|331627_332824_+|TIGR02678-family-protein
METTFDDKAKEALAALFEQFWIIRDKEPDLYQLVRECEHVLKRYVEEKFGYRLIVHRYFAKLEKIPAEPEPWMGIESFQEPLDYALFCCLMAYLEGKAVEEKFLLSDVCEEIRAMYPGDLPVDWTNYSHRRALIRVLKTAEQIGLVRRMDGEIEAFAQHVEEEALYEVPVLARYFMRTYPKDLLQYESIDELLAEEWKASPQDYRRHRLYRKLFLSPAVHRTEGDEQDFYYLRNFRHRLRDDIEAHTPFRYELYKNAAMLTLPERQAPYTVFPDQKGTSEIILHFAALVRERLGEYPPDEYGRIRLTPEQFSAWLADCRRRYGAGWGKTYRDMSAAELVREMLAALNEWRMADVEHDTGMIVLYPLLGRLCGRYPDDFDAKEGEEHGESMGASSRGAD
>NC_014915.1|WP_013522858.1|330134_331625_+|TIGR02677-family-protein
MDATWLKPIVETKYLSTENAHRYRAILRYFYIQHERMRQYLFPEEVYTFLKQHEEFADYTEEELQQDLDQLVKWNNLIARQETAHVRTIEEFKKKRFRYQCSPYTVEIERMIRTLEQLGDSFGGSLEKTRFDRLYASLSRMETIIASDFQEQPDEMHQVWEETFDYFKKIIQNSADYIAYLHGENLEERMTSESFLVYKEQFTAYLRDFIVALQKTSMQIEQLLEDLPEEGVRQFIEHVVDYERLIPRFADALPPRAVQIEEKWETWRSLCEWFLGRDGRESELSFLQYQTNEAIRRLTRVVQRLGERHHHFRSRKGDYLHLARWFSRLESIEEAHCLSAVVFGCFHTKHLVADFGATDNIYRDVWDEPPAEWVTKPRVRHYGEKKKPQAIEDKEREKEEARLRYLEEKAREEAELKQLVTDGKIVLADLPEVTPYVRKTLLGWIAKAMGREGQAMKTENGWVVNVVNKEGTICLRAEDGELVMPNYEIHVLSGGE
>NC_014915.1|WP_013522857.1|329258_329990_-|coiled-coil-protein
MEALLREILHEVKATRTAVESLEQRVGALEGQVANLNERTGALEVLAANLNERTGALEAQMAQLNERTSALEQQFTQLNERTSNLEHQVVQLNERMGTVEHQVAQLNERMGTVEHQVAQLNERMGTVEHQVAQLNERMGTVEHQVAQLNEQTNTLAQRIDLLDERTNETKAIAEALRHGQEVLAAKYEAMAHDLHHMKGDLTRITSILEDKVLPALAEHEAGLHVLNARVFKTESALHRLVHA
>NC_014915.1|WP_013522856.1|327885_328788_-|substrate-binding-region-of-ABC-type-glycine-betaine-transporter
MLRKWMMSLLAVGLVFGLAACSGTSDAKGKIVISGKKFTEQVILTHLLAEYVKANTDLDVEVKDSLGGAFMLQQAIENGDVDMYVEYTGTGYLNILKQPYDPAKTPEQIYNETKKLYKEKYNIAWLKPLGFNNTYALAMRRDLAEKLGVKTYSDLAKHSSSLTFGSDAEFFERSDGYDGLVDTYGFQFKKKVTIDPDLQYEAAKNSEIDVITAYTTDARIKKYDLVVLKDDKQYFPPYHAVPIIRQEVLDANPGLEKKLNKLANILTDEKMMELNGQVNLEGKQPREVALDFLKAEGLID
>NC_014915.1|WP_013522855.1|326741_327869_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MIRFENVTKQYEDGFVALKNINLEVRKGELVALIGPSGCGKTTTMRMINRLIEPTSGKVYIDGQDISQLDPVELRRNIGYVIQQIGLFPHMTIAENIALVPKLKKWEKHAYEKRVDELLELVGLDPATFKHRYPSELSGGQQQRVGVVRALAAEPDIILMDEPFSALDPISREQLQDDIVRLQEEIHKTIVFVTHDMDEAIKIADRIALMKDGEIVQFATPDQMLRRPANSFVREFIGEDRLRTRQTAVPTAEDLMSVDVATISPRRGLAEAFRLMKAKKVDSLIVVDKKQAFLGIVTLKQIEKRYQEEHLLVADIADYDVTTLAKEADVTNVAALFQDPDVRIIPVLDGDQLVGGITRSSMMRALAEWTFQQHA
>NC_014915.1|WP_013522854.1|325857_326487_-|ABC-transporter-permease
MELLQTFIERKNDIWIAFQEHVLLSAIAMSIAIVIAVPLGIALTRYRKLAEPIIGVAAIIQTIPSLALLGFMLPLFGIGKLPAIIALTLYALLPILRNTYTGILGVDPALVDAGRGMGMTSRQILWMVELPLSLPVIMAGVRTATVLTIGVAALATFIGAGGLGDLIDRGLRIADKNLILTGAIPAAILAIVFDWLLRKVEKKVTPKGL
>NC_014915.1|WP_013522853.1|324822_325410_+|GNAT-family-N-acetyltransferase
MKIKDVFGDLPTLTTERLILRKLTLDDAYDLFDYASNSENCKYLPWRPHHTIEDSIQFLEFVIKSYKEGSLAPWGIVSKADNKMIGTIDIVKWLPNHHKAEIGFVLSYKYWGKGLAVEAANKIIEFGFDKMELNRIEAFAMIENVQSLRVLQKLGMQFEGVIREHWYIKGKFRDMAIYSILKRDYFKSRDGLQNA
>NC_014915.1|WP_013522863.1|341179_342895_+|TIGR02556-family-CRISPR-associated-protein
MIEAIAQIGKMALEKQGEASVVDQLVENPGYPSCVLISLRVDGEGSTVWEGCEVEECGSDYKKYLFRSGSTRGTNYSPTARITTIENTYDQKVLGWFRKVNRVMDDPFLRSIEHVLVQQQEAILHEIKDKLSLSGERAIVSLKINGAYLYDWMSFQDAFLYLVNEKDMELAAHHQVCAICGERQDTVIGKLSVFRFYTLDKPGFITGGFDEAKAWRNYPVCLSCKSHIEEGRKFIESYLQYRFYGFSYLAIPKLLIPAGRDVLDELLEYLVNGKKDIRIHQDQAESFMTTEEDLLGTLQDYDNSLSLQLLFLQKIQSAERILLLIEDVLPSRISELFRSKRVTEALLYGEDRYPFHFGFIRTFFPSGVYDKYFLQVVEYVFQKKPLSISFFSPFFMEQLRADFHDYEAGDGSFVAKTRQAIAVMIFLEQAGVLVRKGDQVVEGKFAHLFETYGGQLESPEKQAVFLLGALTQMLLDIQQQQRGSKPFLKQLMGLKMDQQAIKGLLPKVIGKLEEYESYYGGHRQLAEEISHLFLSSSPRWKLSVDELNFYFACGMNLVSKVKEIVWNKEEQ
>NC_014915.1|WP_013522864.1|342896_343853_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MVKQRSELLFLYDVQWANPNGDPVDGNKPRIDEETGKNIVTDVRLKRTIRDYLYEYRHQEIFVREIAQDDDYIQDAKARAEDFLVKDGEKLDKSKLTLSEMKKIINDEVLRQCIDVRLFGVTLPIEKSSKEKSSITHTGPVQFKMGQSLHRVKLEYIKGTGAFASGGQMTQKTFREEYVLPYSLIAFYGVINETAARFTRLTEEDVELLVDAMWEGTKNLISRSKVGHVPRLLLRVVYQEPHFHIGELDKYISLHTEKAEEEIRDVQDYVLDVSRLIEVLAREKEKIANIELRQDERLVCNENLVDRLRQEGIVVDIR
>NC_014915.1|WP_013522865.1|343868_344612_+|type-I-B-CRISPR-associated-protein-Cas5
MNVLVFDIRADFGHFRQLYSTSSPLTHSFIPPTAFFGLLGAITGVGKEENEYLRVFNHKTTNMAIRLMGPVRKTRVGINYVNTKGNIWVPKQRREGARTQIRVEFLRFPHFRCYVSMNDHERFSYLIDLVRQHKSVYTPCLGLSECLADVQFVAMEDFRFVQGAERKTVSICSVLPRKDVQVLEVEEGKEYRKERVAWEMDPERVVSRYEEVIFEAAGRPILASVPHYWENEQGERVVFFYSDGKGE
>NC_014915.1|WP_013522866.1|344613_346944_+|CRISPR-associated-helicase/endonuclease-Cas3
MYSHPHYLLSEHLRGVEQLSSLFLSEKSVRLAEPVLLDKVNRWIALFHDLGKSHAFFQQYIQSPDTFQGPAALKSHALLSAVLLAVFLKDQGVDEFWRLLAFLVVKRHHGNLDDWLEELKRMGEETKALLKRQVEAVDYSALAEQMALAGFGKEGNWTKETWLAWLDEFFTEARSLRRFIMSWNRRNESLAPYVQVLFLFSLLIDADKSEAGIVQKQSWSFSKRKDVPVDLVLRYKQQQSWHQTALNQLRERAFQEVDRTPIDLSQHFYRLNLPTGMGKTLASLHFALRLREKIEQQQGVKPRIIYSLPFLSVIDQTANVLKEVFSVNGVEEDHQLWLAHHHLADIRYTTKQDDERYDVDYEAAKLLIEGWHSELIVTTFVQLFETMFSNRNASLRKFHRLANSIILIDEVQAVPHRYWLAIRRLFAAMAEEIGCYFLFSSATDPKWFPEAVSLVDEQAYFQPLSRVTLYPHINEPMTIEEFARQMEWEEGKTYLFILNTIESAKAFYHALLEEGIDETEVIFLSTHIPPKERLRRIMAAKHGEYRIVVSTQLIEAGVDVDFDVVYRDLAPLDSIQQAAGRCNRHGRRKGEVHVVRLTDNRRLYASYIYDAIRLDITQTLLKGKEKVDEGQFLQLITSYFETLAARMSNAESERLLKGMMTLYFDGEEAIDRIPVSHFRLIEGDGEKINVFIELDEEAADVFREYEEILRLGDRWERRKRFAALKSRFSQYVIAIPVKVDHRPPIVHGIGYVGRDSLNDFYDETLGYRTKSEGLIW
>NC_014915.1|WP_013522867.1|346953_347463_+|CRISPR-associated-protein-Cas4
MEYEMPVTGTDIWYYYICPREVWLMKHQIAPDQEDEALEIGRFLSETYYQRDKKELSIGHIVIDRIRQENGELIIGEVKKSSSYSKSARMQLLYYLDTLRQVGIEAKGELLFPKERKKEQVEWTEEARSELERAITDIRRIARMSVPPPPKKISFCGKCAYREYCWAEE
>NC_014915.1|WP_013522868.1|347466_348468_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKTLYIFQNGELRRKDHSLYFETEERKRYIPVENTNDIYIFGEVDVSKRFLEFAAQKEIIVHYFNHYGYYVGSFYPREHLNSGHVVLKQAEHYIDPAKRLELACLFVQGSIRQMERVLKYYRSRLSDPEELEKALQLIEREEGKLSQANTVEQLMAVEGHIREAYYASFDAILRHPDFVFEKRTKRPPHNRLNALISFGNSIVYTMCLSEIYKTYLDPRIGFLHSTNFRRFSLNLDIAEIFKPIIVDRLIFTLVNKRMLSSKHFEKLTNGIVLNEEGRKLFVSELEKKMQTTVQHRHLGKSVSYRRLIRLELYKVQKHILGEKMYEPYAARW
>NC_014915.1|WP_013522869.1|348478_348742_+|CRISPR-associated-endonuclease-Cas2
MFVILVYDFNEKRVAKALKIARKYLHWVQNSVFEGEITSANYEKLKMELRQLMDPDEDSVIFYTFRTQKYSKREEMGLKKGGDEFIL
>NC_014915.1|WP_013522870.1|348778_349525_+|CRISPR-associated-endoribonuclease-Cas6
MRLTVTMSGRQGTVSLPLHYQHLLQGLLYRSLENEQLAAFLHDRGFRHGKRSFKLFTFSRLFGTHQVNRERKTIHFLGDFQWHIDTALLELTQQLGQRFLVQREIELYGQLIEVKSVKMESVDIRGHEIDVVMLSPLTVYSTYETMDGRKKTQFFDPDDEVFPHLIELNFCHKYAAYYGVPPAERLSIQPIYVHRRHRVVTLFKDMYITGWMGHYRLCSSPEQLTFLYHVGLGSRNSQGFGMFRLASG
>NC_014915.1|WP_013522871.1|352687_353884_+|CRISPR-associated-protein
MYQHIVVTCGVSLFGNRNIFSMNRDETMGEIRPWLSSRNIDEEKQEKIDQWIRHARQFAHEATRDPNRVSAEYSMIYELRRQGKLAERPTVVLIVTETVGGRIVEAILTRLLEEDFQANVRIIYVDVDVNHPRRMQETLGEYMWKVASALSHGEPSTTCFAPIGGYKVMTSLGYIVGAFLHYPTAYMHEDGQVLHEIPPVPIHMDEQFVHEHFDLLRKCQRDLVNAASLSYHEKQCILRYPFLFQQEEGFVYLSAFGQFLLEHEKYKHLFGTTFFASDQVSDMLRHNHHQSLFVHQQLKELVKKLKHKEGDVAVLYHEKSFKTIDTRKVKYHLYKGASNGQTAFRLAYRYDEKEDCLYANYLWLDHNRYEREAAKGKGIYEDNSPFVDMTKQLVGMGR
>NC_014915.1|WP_013522872.1|353886_355227_+|TIGR02221-family-CRISPR-associated-protein
MGRRVLLSFLGLGDYEYCYYTYEGKTSTYTRFIQTAVYELFRNDEPMDVVVFATKEAQDRNGQDRKKGDKLLEGIGTAFSRIAPEANVKIVEIESGQDEQANWRLFDRIMDEIKEGDTIYFDITHSFRSIPFVALIVLNYARLVKKADIGAIIYGWFEVLGRPIDVEQMPEEQRVAPIVNLTSMAKLLDWTNGVDQFLRTGDASIIQALTAKENSEVFRNPSLSQAVKDEVKELRELTKRLDQTEKAIRTCRSLQIDEEVQKFHEQLGRVRSASAEAIKPLVPLLDVMEKKYAMFDDDPIMNSWKAVRWCLDHGLIQQALTMLEENAVTAVCRVLGLDLRNEKARGDVHSAIEILLRDIPKEEWRVRSVERVEQIIDFLSPYKGDLKRFSTLKERRNDINHAGARPQPLKAEKFWPDAEQSFRELGAFFERMSALAKSMQTVKGNG

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Crispr_ID: NC_014915_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014915_2

349707-352139

TypeIII

Consensus_repeat	Method
GTTTTTATCGTACCTATGAGGGATTGAAAC	PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRT

36 spacers

cas6,cas2,cas1,cas4,cas3,cas5,cas7,cas8b1,csm6,csx1,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7

The CRISPR arrays of NC_014915_2

>merge|NC_014915|2|349707-352139|PILER-CR,CRISPRCasFinder,CRT
GTTTTTATCGTACCTATGAGGGATTGAAACATTTTTTGTTTCGGTTTCCCCTCGCGCTCCCCTTCGTTTTTATCGTACCTATGAGGGATTGAAACCGAACCATCCGCTCGAAGGTTGATCGGCTAATGCCGTTTTTATCGTACCTATGAGGGATTGAAACTCAGGATAGAGAATGGTCACCTGCACAGGCTGGGTCGTTTTTATCGTACCTATGAGGGATTGAAACCCAATCTATTTCCAACGGTGGAATAGCATCGGTATTCGTTTTTATCGTACCTATGAGGGATTGAAACATGGGTATTGTCCCAATAAGTCGCCGAAACATAGTTCCCGTTTTTATCGTACCTATGAGGGATTGAAACGCTTCACGATGATCCGGCCGACCACCCTACCGGCTCGTTTTTATCGTACCTATGAGGGATTGAAACTAAAAGTGGCTTCCGGTTTATTCAAAATACTTTCCGGCGTTTTTATCGTACCTATGAGGGATTGAAACCCCGACATGTTCCGAAACTTTAACTCTGGGGCGTTGACGTTTTTATCGTACCTATGAGGGATTGAAACTCGTTCGCACCACACCAAATGTAGTCGGCTTTTCGACGGGTTTTTATCGTACCTATGAGGGATTGAAACAGACCATGACGCGAATTCAAGATTTGCGTTTGGCCTTGGTTTTTATCGTACCTATGAGGGATTGAAACCCTTCAGGAAGATTGATAGCATTATCCGTATTATTGAGTTTTTATCGTACCTATGAGGGATTGAAACAAGGTTTAATCGAAGGTATGAAGGCGATGACCGGAGTTTTTATCGTACCTATGAGGGATTGAAACAAAAACCTTTTCTTCCTTTTTGAAAGGCTTACAAAAGTTTTTATCGTACCTATGAGGGATTGAAACTCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCGGTTTTTATCGTACCTATGAGGGATTGAAACTTTATTGACGGTCTTTTTTGCTTCTTTTGCAGCTTGGTTTTTATCGTACCTATGAGGGATTGAAACTTTTTCATACAGCCTTGCCAGTTCTCTACGCACTTCATTGTTTTTATCGTACCTATGAGGGATTGAAACTCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCGGTTTTTATCGTACCTATGAGGGATTGAAACTTTATTGACGGTCTTTTTTGCTTCTTTTGCAGCTTGGTTTTTATCGTACCTATGAGGGATTGAAACTTTTTCATACAGCCTTGCCAGTTCTCTACGCACTTCATTGTTTTTATCGTACCTATGAGGGATTGAAACTCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCGGTTTTTATCGTACCTATGAGGGATTGAAACTTCAAGACTTCCTCCGGAGAGCTATCCGGAGAAGCAGCGTTTTTATCGTACCTATGAGGGATTGAAACACAATACGGCTAAATTCATCTTCGCAGCCAACCACGGTTTTTATCGTACCTATGAGGGATTGAAACAGGTGACCATTGATAAAAAAGAAACAGAAAAACTTCGTTTTTATCGTACCTATGAGGGATTGAAACGGCGGCACGATTGCGATCAACATCCAAAACATGACCGTTTTTATCGTACCTATGAGGGATTGAAACATCTTTTCGGTGATTGTACTCATCGTTCCGTCTGTGTTTTTATCGTACCTATGAGGGATTGAAACCAATATTCCAGCAATAGGTGACGTTCCAATCGAGACAGTTTTTATCGTACCTATGAGGGATTGAAACCCAGTTCGACCCGTTCCACCACTCATATAAATAAATCGTTTTTATCGTACCTATGAGGGATTGAAACGGGGATGGGACGACCACCAACCGAACCACGCCTGTCGTTTTTATCGTACCTATGAGGGATTGAAACACGACGATTGCCAAAGAATCGCCAGAACACTCACAGGCAGTTTTTATCGTACCTATGAGGGATTGAAACTTCAGAATGAGTCCTGTCACGGTATACCCATTTTTGTTTTTATCGTACCTATGAGGGATTGAAACAAAATATGACGTTCGATCAATGGAAAAAGGAGCGGTTGTTTTTATCGTACCTATGAGGGATTGAAACATCATCGGGGGCTGGCGGCAGGAACAAGCACAGCAGTTTTTATCGTACCTATGAGGGATTGAAACACTACACATTGTACGCATGCGGAAACGGCTACACATACGTTTTTATCGTACCTATGAGGGATTGAAACAGAGGAAACGCCGCCGTTGTAAACATAGCTTTCAAAGTTTTTATCGTACCTATGAGGGATTGAAACGAAAATCTCGGTTTCGTGGAAGTGTCAGTAAGATCGTTTTTATCGTACCTATGAGGGATTGAAACCTCCGCAAACGACCACGCCATCGGGTGGCCAGCGGTTTTTATCGTACCTATGAGGGATTGAAAC

>NC_014915|2|2|349707-352139|PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATTTTTTGTTTCGGTTTCCCCTCGCGCTCCCCTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CGAACCATCCGCTCGAAGGTTGATCGGCTAATGCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCAGGATAGAGAATGGTCACCTGCACAGGCTGGGTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAATCTATTTCCAACGGTGGAATAGCATCGGTATTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATGGGTATTGTCCCAATAAGTCGCCGAAACATAGTTCCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCTTCACGATGATCCGGCCGACCACCCTACCGGCTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TAAAAGTGGCTTCCGGTTTATTCAAAATACTTTCCGGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCCGACATGTTCCGAAACTTTAACTCTGGGGCGTTGAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGTTCGCACCACACCAAATGTAGTCGGCTTTTCGACGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGACCATGACGCGAATTCAAGATTTGCGTTTGGCCTTG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCTTCAGGAAGATTGATAGCATTATCCGTATTATTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGGTTTAATCGAAGGTATGAAGGCGATGACCGGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAAACCTTTTCTTCCTTTTTGAAAGGCTTACAAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTATTGACGGTCTTTTTTGCTTCTTTTGCAGCTTG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTCATACAGCCTTGCCAGTTCTCTACGCACTTCATT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTATTGACGGTCTTTTTTGCTTCTTTTGCAGCTTG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTCATACAGCCTTGCCAGTTCTCTACGCACTTCATT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCAAGACTTCCTCCGGAGAGCTATCCGGAGAAGCAGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACAATACGGCTAAATTCATCTTCGCAGCCAACCACG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGGTGACCATTGATAAAAAAGAAACAGAAAAACTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGCGGCACGATTGCGATCAACATCCAAAACATGACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATCTTTTCGGTGATTGTACTCATCGTTCCGTCTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	CAATATTCCAGCAATAGGTGACGTTCCAATCGAGACA
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAGTTCGACCCGTTCCACCACTCATATAAATAAATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGGGATGGGACGACCACCAACCGAACCACGCCTGTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACGACGATTGCCAAAGAATCGCCAGAACACTCACAGGCA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCAGAATGAGTCCTGTCACGGTATACCCATTTTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAATATGACGTTCGATCAATGGAAAAAGGAGCGGTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATCATCGGGGGCTGGCGGCAGGAACAAGCACAGCA
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACTACACATTGTACGCATGCGGAAACGGCTACACATAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGAGGAAACGCCGCCGTTGTAAACATAGCTTTCAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GAAAATCTCGGTTTCGTGGAAGTGTCAGTAAGATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTCCGCAAACGACCACGCCATCGGGTGGCCAGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC

>NC_014915|2|2|349707-352139|CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATTTTTTGTTTCGGTTTCCCCTCGCGCTCCCCTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CGAACCATCCGCTCGAAGGTTGATCGGCTAATGCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCAGGATAGAGAATGGTCACCTGCACAGGCTGGGTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAATCTATTTCCAACGGTGGAATAGCATCGGTATTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATGGGTATTGTCCCAATAAGTCGCCGAAACATAGTTCCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCTTCACGATGATCCGGCCGACCACCCTACCGGCTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TAAAAGTGGCTTCCGGTTTATTCAAAATACTTTCCGGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCCGACATGTTCCGAAACTTTAACTCTGGGGCGTTGAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGTTCGCACCACACCAAATGTAGTCGGCTTTTCGACGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGACCATGACGCGAATTCAAGATTTGCGTTTGGCCTTG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCTTCAGGAAGATTGATAGCATTATCCGTATTATTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGGTTTAATCGAAGGTATGAAGGCGATGACCGGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAAACCTTTTCTTCCTTTTTGAAAGGCTTACAAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTATTGACGGTCTTTTTTGCTTCTTTTGCAGCTTG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTCATACAGCCTTGCCAGTTCTCTACGCACTTCATT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTATTGACGGTCTTTTTTGCTTCTTTTGCAGCTTG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTCATACAGCCTTGCCAGTTCTCTACGCACTTCATT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCAAGACTTCCTCCGGAGAGCTATCCGGAGAAGCAGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACAATACGGCTAAATTCATCTTCGCAGCCAACCACG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGGTGACCATTGATAAAAAAGAAACAGAAAAACTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGCGGCACGATTGCGATCAACATCCAAAACATGACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATCTTTTCGGTGATTGTACTCATCGTTCCGTCTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	CAATATTCCAGCAATAGGTGACGTTCCAATCGAGACA
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAGTTCGACCCGTTCCACCACTCATATAAATAAATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGGGATGGGACGACCACCAACCGAACCACGCCTGTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACGACGATTGCCAAAGAATCGCCAGAACACTCACAGGCA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCAGAATGAGTCCTGTCACGGTATACCCATTTTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAATATGACGTTCGATCAATGGAAAAAGGAGCGGTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATCATCGGGGGCTGGCGGCAGGAACAAGCACAGCA
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACTACACATTGTACGCATGCGGAAACGGCTACACATAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGAGGAAACGCCGCCGTTGTAAACATAGCTTTCAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GAAAATCTCGGTTTCGTGGAAGTGTCAGTAAGATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTCCGCAAACGACCACGCCATCGGGTGGCCAGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC

>NC_014915|2|2|349707-352139|CRT
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATTTTTTGTTTCGGTTTCCCCTCGCGCTCCCCTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CGAACCATCCGCTCGAAGGTTGATCGGCTAATGCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCAGGATAGAGAATGGTCACCTGCACAGGCTGGGTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAATCTATTTCCAACGGTGGAATAGCATCGGTATTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATGGGTATTGTCCCAATAAGTCGCCGAAACATAGTTCCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCTTCACGATGATCCGGCCGACCACCCTACCGGCTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TAAAAGTGGCTTCCGGTTTATTCAAAATACTTTCCGGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCCGACATGTTCCGAAACTTTAACTCTGGGGCGTTGAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGTTCGCACCACACCAAATGTAGTCGGCTTTTCGACGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGACCATGACGCGAATTCAAGATTTGCGTTTGGCCTTG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCTTCAGGAAGATTGATAGCATTATCCGTATTATTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGGTTTAATCGAAGGTATGAAGGCGATGACCGGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAAACCTTTTCTTCCTTTTTGAAAGGCTTACAAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTATTGACGGTCTTTTTTGCTTCTTTTGCAGCTTG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTCATACAGCCTTGCCAGTTCTCTACGCACTTCATT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTATTGACGGTCTTTTTTGCTTCTTTTGCAGCTTG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTTTTCATACAGCCTTGCCAGTTCTCTACGCACTTCATT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCAAGCGCAATGAGTTTGGTAAAGTCCTCGCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCAAGACTTCCTCCGGAGAGCTATCCGGAGAAGCAGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACAATACGGCTAAATTCATCTTCGCAGCCAACCACG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGGTGACCATTGATAAAAAAGAAACAGAAAAACTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGCGGCACGATTGCGATCAACATCCAAAACATGACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATCTTTTCGGTGATTGTACTCATCGTTCCGTCTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	CAATATTCCAGCAATAGGTGACGTTCCAATCGAGACA
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAGTTCGACCCGTTCCACCACTCATATAAATAAATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGGGATGGGACGACCACCAACCGAACCACGCCTGTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACGACGATTGCCAAAGAATCGCCAGAACACTCACAGGCA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCAGAATGAGTCCTGTCACGGTATACCCATTTTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAATATGACGTTCGATCAATGGAAAAAGGAGCGGTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATCATCGGGGGCTGGCGGCAGGAACAAGCACAGCA
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACTACACATTGTACGCATGCGGAAACGGCTACACATAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AGAGGAAACGCCGCCGTTGTAAACATAGCTTTCAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GAAAATCTCGGTTTCGTGGAAGTGTCAGTAAGATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTCCGCAAACGACCACGCCATCGGGTGGCCAGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014915.1\|WP_013522875.1\|357771_358902_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
NC_014915.1\|WP_013522874.1\|356131_357772_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NC_014915.1\|WP_013522876.1\|358901_359795_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NC_014915.1\|WP_013522880.1\|366369_367413_+\|P1-family-peptidase	unknown	unknown	gnl\|CDD\|239071
NC_014915.1\|WP_013522869.1\|348478_348742_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_014915.1\|WP_013522861.1\|336901_338122_+\|TIGR02679-family-protein	unknown	unknown	gnl\|CDD\|274255
NC_014915.1\|WP_013522878.1\|360229_361378_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|187792
NC_014915.1\|WP_013522872.1\|353886_355227_+\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl\|CDD\|378186
NC_014915.1\|WP_013522868.1\|347466_348468_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_014915.1\|WP_013522862.1\|338266_339181_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NC_014915.1\|WP_013522870.1\|348778_349525_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_014915.1\|WP_013522865.1\|343868_344612_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_014915.1\|WP_041469329.1\|361609_363277_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_014915.1\|WP_013522864.1\|342896_343853_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_014915.1\|WP_013522867.1\|346953_347463_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_014915.1\|WP_013522871.1\|352687_353884_+\|CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl\|CDD\|187873
NC_014915.1\|WP_013522863.1\|341179_342895_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_014915.1\|WP_013522873.1\|355226_356135_+\|CRISPR-associated-protein	unknown	unknown	gnl\|CDD\|273859
NC_014915.1\|WP_013522877.1\|359808_360216_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	gnl\|CDD\|378242
NC_014915.1\|WP_013522866.1\|344613_346944_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_014915.1\|WP_013522875.1\|357771_358902_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	4.5e-58	192.2	0.0
NC_014915.1\|WP_013522874.1\|356131_357772_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	8.3e-79	260.3	1.6
NC_014915.1\|WP_013522876.1\|358901_359795_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	2.5e-71	235.3	0.0
NC_014915.1\|WP_013522869.1\|348478_348742_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	4.8e-30	98.5	0.2
NC_014915.1\|WP_013522878.1\|360229_361378_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	4.4e-40	132.6	0.0
NC_014915.1\|WP_013522872.1\|353886_355227_+\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	7.3e-74	243.7	0.1
NC_014915.1\|WP_013522868.1\|347466_348468_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	4.2e-139	457.9	8.7
NC_014915.1\|WP_013522870.1\|348778_349525_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	1.3e-39	131.2	0.0
NC_014915.1\|WP_013522865.1\|343868_344612_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	1.4e-37	124.3	0.0
NC_014915.1\|WP_013522864.1\|342896_343853_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	4.6e-95	312.9	2.3
NC_014915.1\|WP_013522867.1\|346953_347463_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	1.6e-53	175.9	0.2
NC_014915.1\|WP_013522871.1\|352687_353884_+\|CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	3.1e-24	80.0	0.0
NC_014915.1\|WP_013522863.1\|341179_342895_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	8.2e-111	366.1	0.0
NC_014915.1\|WP_013522877.1\|359808_360216_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	1.9e-32	106.9	0.1
NC_014915.1\|WP_013522866.1\|344613_346944_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	9.5e-58	190.7	0.8

Protein	Function_ID	Function_description	E-value
NC_014915.1\|WP_013522875.1\|357771_358902_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	1.50055e-45
NC_014915.1\|WP_013522874.1\|356131_357772_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	3.29957e-77
NC_014915.1\|WP_013522876.1\|358901_359795_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	8.03044e-72
NC_014915.1\|WP_013522880.1\|366369_367413_+\|P1-family-peptidase	gnl\|CDD\|239071	cd02253, DmpA, L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active heterodimeric form. The cleavage results in two polypeptide chains, with one chain containing an N-terminal nucleophile. This group represents one of the rare aminopeptidases that are not metalloenzymes. DmpA shows similarity in catalytic mechanism to N-terminal nucleophile (Ntn) hydrolases, which are enzymes that catalyze the cleavage of amide bonds through the nucleophilic attack of the side chain of an N-terminal serine, threonine, or cysteine.	5.15513e-169
NC_014915.1\|WP_013522869.1\|348478_348742_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.421e-34
NC_014915.1\|WP_013522861.1\|336901_338122_+\|TIGR02679-family-protein	gnl\|CDD\|274255	TIGR02679, conserved_hypothetical_protein, TIGR02679 family protein. Members of this protein belong to a conserved gene four-gene neighborhood found sporadically in a phylogenetically broad range of bacteria: Nocardia farcinica, Symbiobacterium thermophilum, and Streptomyces avermitilis (Actinobacteria), Geobacillus kaustophilus (Firmicutes), Azoarcus sp. EbN1 and Ralstonia solanacearum (Betaproteobacteria). [Hypothetical proteins, Conserved].	3.05546e-140
NC_014915.1\|WP_013522878.1\|360229_361378_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|187792	cd09661, Cmr6_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.20342e-38
NC_014915.1\|WP_013522872.1\|353886_355227_+\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	8.05541e-64
NC_014915.1\|WP_013522868.1\|347466_348468_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	1.11603e-171
NC_014915.1\|WP_013522862.1\|338266_339181_+\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.51656e-15
NC_014915.1\|WP_013522870.1\|348778_349525_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.34584e-34
NC_014915.1\|WP_013522865.1\|343868_344612_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	3.79723e-31
NC_014915.1\|WP_041469329.1\|361609_363277_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	2.34312e-27
NC_014915.1\|WP_013522864.1\|342896_343853_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	4.88644e-92
NC_014915.1\|WP_013522867.1\|346953_347463_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	2.12896e-73
NC_014915.1\|WP_013522871.1\|352687_353884_+\|CRISPR-associated-protein	gnl\|CDD\|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	1.96696e-15
NC_014915.1\|WP_013522863.1\|341179_342895_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.69786e-150
NC_014915.1\|WP_013522873.1\|355226_356135_+\|CRISPR-associated-protein	gnl\|CDD\|273859	TIGR01894, hypothetical_protein, CRISPR type III-B/RAMP module RAMP protein Cmr1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model represents the region of stongest conservation, the N-terminal half, of one such family, represented by TM1795 from Thermotoga maritima. This protein is the first of a set of six genes, mostly from the RAMP superfamily, that we designated the CRISPR-associated RAMP module.	1.82179e-06
NC_014915.1\|WP_013522877.1\|359808_360216_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	3.82008e-35
NC_014915.1\|WP_013522866.1\|344613_346944_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.07841e-46

>NC_014915.1|WP_013522870.1|348778_349525_+|CRISPR-associated-endoribonuclease-Cas6
MRLTVTMSGRQGTVSLPLHYQHLLQGLLYRSLENEQLAAFLHDRGFRHGKRSFKLFTFSRLFGTHQVNRERKTIHFLGDFQWHIDTALLELTQQLGQRFLVQREIELYGQLIEVKSVKMESVDIRGHEIDVVMLSPLTVYSTYETMDGRKKTQFFDPDDEVFPHLIELNFCHKYAAYYGVPPAERLSIQPIYVHRRHRVVTLFKDMYITGWMGHYRLCSSPEQLTFLYHVGLGSRNSQGFGMFRLASG
>NC_014915.1|WP_013522869.1|348478_348742_+|CRISPR-associated-endonuclease-Cas2
MFVILVYDFNEKRVAKALKIARKYLHWVQNSVFEGEITSANYEKLKMELRQLMDPDEDSVIFYTFRTQKYSKREEMGLKKGGDEFIL
>NC_014915.1|WP_013522868.1|347466_348468_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKTLYIFQNGELRRKDHSLYFETEERKRYIPVENTNDIYIFGEVDVSKRFLEFAAQKEIIVHYFNHYGYYVGSFYPREHLNSGHVVLKQAEHYIDPAKRLELACLFVQGSIRQMERVLKYYRSRLSDPEELEKALQLIEREEGKLSQANTVEQLMAVEGHIREAYYASFDAILRHPDFVFEKRTKRPPHNRLNALISFGNSIVYTMCLSEIYKTYLDPRIGFLHSTNFRRFSLNLDIAEIFKPIIVDRLIFTLVNKRMLSSKHFEKLTNGIVLNEEGRKLFVSELEKKMQTTVQHRHLGKSVSYRRLIRLELYKVQKHILGEKMYEPYAARW
>NC_014915.1|WP_013522867.1|346953_347463_+|CRISPR-associated-protein-Cas4
MEYEMPVTGTDIWYYYICPREVWLMKHQIAPDQEDEALEIGRFLSETYYQRDKKELSIGHIVIDRIRQENGELIIGEVKKSSSYSKSARMQLLYYLDTLRQVGIEAKGELLFPKERKKEQVEWTEEARSELERAITDIRRIARMSVPPPPKKISFCGKCAYREYCWAEE
>NC_014915.1|WP_013522866.1|344613_346944_+|CRISPR-associated-helicase/endonuclease-Cas3
MYSHPHYLLSEHLRGVEQLSSLFLSEKSVRLAEPVLLDKVNRWIALFHDLGKSHAFFQQYIQSPDTFQGPAALKSHALLSAVLLAVFLKDQGVDEFWRLLAFLVVKRHHGNLDDWLEELKRMGEETKALLKRQVEAVDYSALAEQMALAGFGKEGNWTKETWLAWLDEFFTEARSLRRFIMSWNRRNESLAPYVQVLFLFSLLIDADKSEAGIVQKQSWSFSKRKDVPVDLVLRYKQQQSWHQTALNQLRERAFQEVDRTPIDLSQHFYRLNLPTGMGKTLASLHFALRLREKIEQQQGVKPRIIYSLPFLSVIDQTANVLKEVFSVNGVEEDHQLWLAHHHLADIRYTTKQDDERYDVDYEAAKLLIEGWHSELIVTTFVQLFETMFSNRNASLRKFHRLANSIILIDEVQAVPHRYWLAIRRLFAAMAEEIGCYFLFSSATDPKWFPEAVSLVDEQAYFQPLSRVTLYPHINEPMTIEEFARQMEWEEGKTYLFILNTIESAKAFYHALLEEGIDETEVIFLSTHIPPKERLRRIMAAKHGEYRIVVSTQLIEAGVDVDFDVVYRDLAPLDSIQQAAGRCNRHGRRKGEVHVVRLTDNRRLYASYIYDAIRLDITQTLLKGKEKVDEGQFLQLITSYFETLAARMSNAESERLLKGMMTLYFDGEEAIDRIPVSHFRLIEGDGEKINVFIELDEEAADVFREYEEILRLGDRWERRKRFAALKSRFSQYVIAIPVKVDHRPPIVHGIGYVGRDSLNDFYDETLGYRTKSEGLIW
>NC_014915.1|WP_013522865.1|343868_344612_+|type-I-B-CRISPR-associated-protein-Cas5
MNVLVFDIRADFGHFRQLYSTSSPLTHSFIPPTAFFGLLGAITGVGKEENEYLRVFNHKTTNMAIRLMGPVRKTRVGINYVNTKGNIWVPKQRREGARTQIRVEFLRFPHFRCYVSMNDHERFSYLIDLVRQHKSVYTPCLGLSECLADVQFVAMEDFRFVQGAERKTVSICSVLPRKDVQVLEVEEGKEYRKERVAWEMDPERVVSRYEEVIFEAAGRPILASVPHYWENEQGERVVFFYSDGKGE
>NC_014915.1|WP_013522864.1|342896_343853_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MVKQRSELLFLYDVQWANPNGDPVDGNKPRIDEETGKNIVTDVRLKRTIRDYLYEYRHQEIFVREIAQDDDYIQDAKARAEDFLVKDGEKLDKSKLTLSEMKKIINDEVLRQCIDVRLFGVTLPIEKSSKEKSSITHTGPVQFKMGQSLHRVKLEYIKGTGAFASGGQMTQKTFREEYVLPYSLIAFYGVINETAARFTRLTEEDVELLVDAMWEGTKNLISRSKVGHVPRLLLRVVYQEPHFHIGELDKYISLHTEKAEEEIRDVQDYVLDVSRLIEVLAREKEKIANIELRQDERLVCNENLVDRLRQEGIVVDIR
>NC_014915.1|WP_013522863.1|341179_342895_+|TIGR02556-family-CRISPR-associated-protein
MIEAIAQIGKMALEKQGEASVVDQLVENPGYPSCVLISLRVDGEGSTVWEGCEVEECGSDYKKYLFRSGSTRGTNYSPTARITTIENTYDQKVLGWFRKVNRVMDDPFLRSIEHVLVQQQEAILHEIKDKLSLSGERAIVSLKINGAYLYDWMSFQDAFLYLVNEKDMELAAHHQVCAICGERQDTVIGKLSVFRFYTLDKPGFITGGFDEAKAWRNYPVCLSCKSHIEEGRKFIESYLQYRFYGFSYLAIPKLLIPAGRDVLDELLEYLVNGKKDIRIHQDQAESFMTTEEDLLGTLQDYDNSLSLQLLFLQKIQSAERILLLIEDVLPSRISELFRSKRVTEALLYGEDRYPFHFGFIRTFFPSGVYDKYFLQVVEYVFQKKPLSISFFSPFFMEQLRADFHDYEAGDGSFVAKTRQAIAVMIFLEQAGVLVRKGDQVVEGKFAHLFETYGGQLESPEKQAVFLLGALTQMLLDIQQQQRGSKPFLKQLMGLKMDQQAIKGLLPKVIGKLEEYESYYGGHRQLAEEISHLFLSSSPRWKLSVDELNFYFACGMNLVSKVKEIVWNKEEQ
>NC_014915.1|WP_013522862.1|338266_339181_+|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAKQRIDHDRLFKELLSTFFEEFLLLFFPNVYEHIDVHHLSFLSEELFTDVTAGEKHRVDLLVETKVKGEDGLVIVHVEHQSYTQRTFPERMFLYFSRLFQKYRRRIVPIAIFSYDEHHDEPSSLIVQFPFLKVLDFRFLTVELRKQPWRQYIHQDNPVAAALLSKMGYNEEEKVEVKKEFLRMLVRLELDEAKQRLLFGFFETYLRLSEEEEAKLRNEVSQMETKEAKQVMELIISYEQRGMEKGIQQGMEQGLKQGMKQGRQKGIEEGKLDVVKRMLAKGYDVDTIHELTGLPVEKIERVKG
>NC_014915.1|WP_013522861.1|336901_338122_+|TIGR02679-family-protein
MSTVKEAAAFFRSEPGFKRLFVEMKRKYESLGRVGGAVSLQSFSKEEREAVAAFFGKDVVRVSLSAFEKQLGQTKFAGVGLVALLEQYFGEPLVPKKERLQAEEDERERFFARLAEEHHWFAAVRGQRFVQTAYEADRDGLEAAVRLVGAALCRLPLSSYMRLPLFAQQVASDPHAFDLSTLPGRLLLSALQATTPGQWDVTSVESVNELLQSVGLLREDILNFVTCANILAETEGGPHPVFSAASETNTALNMPLRDVLSLVSVRPARGGTVYIVENAGVFSTLLDTRAPLVSTNGQMNLATMKLLDLLAASGAKLYYSGDFDPEGLAMAERLLERYGQSVTLWRFSLDDYAAANPVVALSSERLAKLASVTSAPLQPLKEEMKRKKKAGYQEAIIGRLTGDING
>NC_014915.1|WP_013522871.1|352687_353884_+|CRISPR-associated-protein
MYQHIVVTCGVSLFGNRNIFSMNRDETMGEIRPWLSSRNIDEEKQEKIDQWIRHARQFAHEATRDPNRVSAEYSMIYELRRQGKLAERPTVVLIVTETVGGRIVEAILTRLLEEDFQANVRIIYVDVDVNHPRRMQETLGEYMWKVASALSHGEPSTTCFAPIGGYKVMTSLGYIVGAFLHYPTAYMHEDGQVLHEIPPVPIHMDEQFVHEHFDLLRKCQRDLVNAASLSYHEKQCILRYPFLFQQEEGFVYLSAFGQFLLEHEKYKHLFGTTFFASDQVSDMLRHNHHQSLFVHQQLKELVKKLKHKEGDVAVLYHEKSFKTIDTRKVKYHLYKGASNGQTAFRLAYRYDEKEDCLYANYLWLDHNRYEREAAKGKGIYEDNSPFVDMTKQLVGMGR
>NC_014915.1|WP_013522872.1|353886_355227_+|TIGR02221-family-CRISPR-associated-protein
MGRRVLLSFLGLGDYEYCYYTYEGKTSTYTRFIQTAVYELFRNDEPMDVVVFATKEAQDRNGQDRKKGDKLLEGIGTAFSRIAPEANVKIVEIESGQDEQANWRLFDRIMDEIKEGDTIYFDITHSFRSIPFVALIVLNYARLVKKADIGAIIYGWFEVLGRPIDVEQMPEEQRVAPIVNLTSMAKLLDWTNGVDQFLRTGDASIIQALTAKENSEVFRNPSLSQAVKDEVKELRELTKRLDQTEKAIRTCRSLQIDEEVQKFHEQLGRVRSASAEAIKPLVPLLDVMEKKYAMFDDDPIMNSWKAVRWCLDHGLIQQALTMLEENAVTAVCRVLGLDLRNEKARGDVHSAIEILLRDIPKEEWRVRSVERVEQIIDFLSPYKGDLKRFSTLKERRNDINHAGARPQPLKAEKFWPDAEQSFRELGAFFERMSALAKSMQTVKGNG
>NC_014915.1|WP_013522873.1|355226_356135_+|CRISPR-associated-protein
MTYQDRSGATAVVQSSYQLVLLTPAAIHGADPREKAEFRLSSLRGVWRYWWRTLQDEPDPEKLLAKEEEWFGGTRKMKQQSPIHLSMAGVMEGTKKENILPHRTSPTLVPALPAGGEVTVTLSVRKRHQERLAQYDWYFQYVLHLASFGQRSRRGFGAVQWIGHQWSNVGEYVESLRMVLEHIGVAGAFSFAERDCLVARRGDIQTQHPVLSAVWIGEGKESAAEVVKAFGKASHEANRYGSLGYMRGKAGKLSSPLWCTVRKIGNWYYPIVTEVRNHDPHYSEPRYEQDRNRFLEIVGVRI
>NC_014915.1|WP_013522874.1|356131_357772_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MTNRYVVIFTVGPVQSFIASARKTEDFWSGSYILSHLVREAIKRFYQFDANCEMIYPLVTEKELRSPSQRDVHIASIPNRLTVIMEGTEEEVCGWLREAEQDVCNVFLDFCFQAVRRVFPHLTDHEQELLERMVEQQVRSFLEIYWVAEPYEPSMSFREVRERAERRLGALKNEKHYIPVSQQGLVCSVCKEREALRLEEIGEFDHYGEIKKKTMSLWQRRAVKFQGTGGDEEDDRRAGRIKDNEFLCGICLGKRAARDYFADLFGTSFPSFPSVLDIGQGDYYAVLLMDGDDMGKWFSGERKDEYSRTSQKLARFAKETVPWIVQERCKGKLVYAGGDDVLAFVPVETALKAAEMLRLAFADERQGLGSGATASFGVVIAHKKAPLQHVLNAARALEQKAKRYYNDKTAQRKDALALAVHTRSGEISEAVLPWIVGEKMVSKLLEEWLGLLKTSLSPNFIFHFASAFAPLLHEKDCPKWENRDMLATELRRLLRRSVKEGSCLDAQDIARYTSTLLVLHEAVRSSYDFLHLLKMLTFFKRSKGRG
>NC_014915.1|WP_013522875.1|357771_358902_+|type-III-B-CRISPR-module-associated-protein-Cmr3
MTKLVLTPADTFFFKNHHATQAGETTVMESMFPPRPNTIYGALRAAYIYAYSSFDEFARGADERVKLWMGTPDERGAFRLHYCALADGDSLFLPLPLDYQVVEEGDSLKAYPLQLAKDRKPSSASTMWRLASSRREKTKSSQHRYVSLSEWKKALLLNQPIASLRTLSSFIVQEEKVGIQLDVSRRTAQEGFLYRVGKHRFLGDSSLVAYIDDGPDFSNVKWARIGGENRPWFIRQHPEEFRLWNDDEKRRIEQDIQRTKMAKIIFLSPAIFANGSRPAAMEGDRWTWPNGAVVTWLAAAIGRPELYGGWDIVRHRPKPRKWMIPAGSVIYVKIERDDDLRLVFSALDGIHLTDEGAEEGFGFAVLASVHESEEEL
>NC_014915.1|WP_013522876.1|358901_359795_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYSIIRPFLLHAVTSVHAGSGSEIGLVDLPIQREKHTGFPKIESSSLKGALRYHMTQALPDETNKLELIFGADKGQESVTQASAIALSDARVLLFPVKSLRGVFAWITCPHVLERWNQEMSVHQEMKGKGEGFQPLPVPGPNTVSADRLIVADGRIILEEYTFPVTVSPEAKQLAEQLSAIIGESSRLRVTDRLVILSDDDFTDFVKLSTEVNARIRISPETGTVDSGALWYEENVPPETFFYSFLYIGHVRGKGVDGLATAEEIERYLVDERKFPSVFQLGGNSTLGRGMMRTIWL
>NC_014915.1|WP_013522877.1|359808_360216_+|type-III-B-CRISPR-module-associated-protein-Cmr5
MGTKVQRVGIENGRAAFAFQEVKQAKEGLKENFENYRSYVKKMPSLIQVNGLGQALAFCFQKKGREYRSIYRSIAKWMKEQFPGQFGKEDMELVEVVVNLSSADYRLWTMETLALLDWMRKFADGMVKDDAEAAK
>NC_014915.1|WP_013522878.1|360229_361378_+|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MLFHPKDTREVMQRANKSAAHLAYHLHYFLEHQWNDKKRVWEPSKRLKPVPILPELKEIGEQLQAQREQAMIEWAQTGYVKKLKARLVGRIIHGLGAGHIRETSLTIHPVYGLPYIPASSVKGLVRHWFIEAYCEGEEKQLNEHEIGREIFGTQGNKGIVQFHDIFLIEGLQLTGDVLAVHMKEYYEGNRAATDDQKPVPVSFWTVMATEVDIYLTANRSAPQNDEETVRLLEAAALWTQQALTEWGIGSKTSSGYGRFAEVYDVTEMEFLPIVQKEQVRLEQQKKEREMLEQRKREEEEKARLALLSPEERLVVEIERLTDSQTDEQRSKDVLYQQVIEQRNRQAALALQAYWQRIGQWGKSVSKKQKQKIDKLQQLLNDE
>NC_014915.1|WP_041469329.1|361609_363277_-|IS1634-family-transposase
MYIRRVTRKNKDGTTVAYLQLAHNEWDPKAKYAKAKVIYSFGREDEVDRAVLERLAKSISRFLSPEQAWEIETLTGEVSDDFQFQSSKRLGGAWLLDQLWRQLGLGEILHSLFASRHHQIPLERLIFAMVANRALHPSSKLAMEEWVEKDVHIPHLPQVASHQLYRAMDELLAVQPELERQVFHAVADLLNLEVDLIYFDTTSSYFEVDPSETPEGESLRKQGFSKDKRPDLVQIVIGLAVTREGVPIRAWVWPGNTMDMTVIKQVKQDLIGWKLGRVISVMDRGFSSEENLRILQQAGGHYIVGEKMRSGKAAVEEALNRRGRYQQVRENLHIKEIIVGDGEARQRYVLVYNPSEAERQRKEREKLLESLKEELEGLRQLPNEAHHKATCRLRSHPSYGKYLRQLKDGTLRIDKQAVREAEKYDGKYLIRTSDDTLSAEDVALGYKQLVDIEQAFRTLKSTLELRPMYHRLEDRIRAHVLLSWLALLLVRIVEIRTHESWPKVRDECERLMLGHFSSKNGDLYQRTELTAKQAQFFAALGLEPPPKILGIHPRA
>NC_014915.1|WP_013522880.1|366369_367413_+|P1-family-peptidase
MRSKLRHLGFSIGTLPTGERNQITDVPGVKVGHVTIREDMDERTVIRTGVTAVLPHGGNWFLEKVPAACFVLNGFGKTVGLVQVEELGAIESPIMLTNTFSVGAVWQGTLEHMLAMTPEIGDTTGSVNIVVGECNDSYLNTARALSVTKEHAKQAIAEARVDMEEGAVGAGTGMMCFGWKGGIGSSSRIAGGMYTVGALVVSNFGRREELRLVPYVPPSFDERDVPPGSIMMIVATDAPLDARQLKRAAVGLARTGSHVHHGSGDIVIAFSNAYMIPHFADSSHQPLPPLVRDDAPLMNELFQAAIEAVEEAIWNSLTMAETTTGRNGRVGEAIPYSLLRWIKWTEK

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Crispr_ID: NC_014915_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014915_3

363492-366113

TypeIII

Consensus_repeat	Method
GTTTTTATCGTACCTATGAGGGATTGAAAC	PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	CRT

39 spacers

cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,csx1,csm6,cas6,RT

The CRISPR arrays of NC_014915_3

>merge|NC_014915|3|363492-366113|PILER-CR,CRISPRCasFinder,CRT
GTTTTTATCGTACCTATGAGGGATTGAAACCCAAGTACCAAAAGTGGCTTTTGGATTTCAACACGATCGTTTTTATCGTACCTATGAGGGATTGAAACATCGGAGCAACGTCCCGCCCGATGTCGCCGACGTCGGTTTTTATCGTACCTATGAGGGATTGAAACTATTCGATTTCGATAAGCCCGCTGGCTTCGAGTATTTGTTTTTATCGTACCTATGAGGGATTGAAACTCCATCGAATCATTCGCTCACCTCCGCAGTCCTCGTTTTTATCGTACCTATGAGGGATTGAAACTCGTCGACTATGCGGAAGCCAATCGCGGGCAGGCGCCGTTTTTATCGTACCTATGAGGGATTGAAACTGGTACTGCGCGCGAATCCGCTGGCATTAGCCATTACCGTTTTTATCGTACCTATGAGGGATTGAAACATATGCCAGTTTGATTTTGTTAAACACCGTTTCAATGCGTTTTTATCGTACCTATGAGGGATTGAAACACATGGTGGCGTCCAGCCTCGCCGGCCAGCGATAAAGAGTTTTTATCGTACCTATGAGGGATTGAAACATTTTTCTAATTACTTTAGTATCATTTACTATTTTTTGTTTTTATCGTACCTATGAGGGATTGAAACTCCTGCCGTTCCACTCACCGCCGTTTCGCTCACCTGCGGTTTTTATCGTACCTATGAGGGATTGAAACTGGTATCGGTAGTAATACTCGCGCGCCGCAAAATCGTTTTTATCGTACCTATGAGGGATTGAAACTCGAAGATGAGCAGATAGCTGATAGCGTCATATTGAACAGTTTTTATCGTACCTATGAGGGATTGAAACGCAGACGGGGACAGACGTATCAGAACATTGCTTGGGTTTTTATCGTACCTATGAGGGATTGAAACATAACCCTGACCCCTTTCTGCCGCAGCAGAGCGATGAAGTTTTTATCGTACCTATGAGGGATTGAAACTTCTCAAGCGCAATCAATTTCCATTTGCGGCTTTCCGTTTTTATCGTACCTATGAGGGATTGAAACAAAAATCGGCGGAGTTTGGAGGAGTTTGGCGTGAAGGTTTTTATCGTACCTATGAGGGATTGAAACAAAGACGACCGTTTCGTCAAAACAGGCAGCCTCCCGGTTTTTATCGTACCTATGAGGGATTGAAACAAACGGAGTATCTTGATAAGCTCGAAGAAAAAAACTGTTTTTATCGTACCTATGAGGGATTGAAACTAATTGAGGTGAAACGAATGGAGAGGCTCGATGTGAGTTTTTATCGTACCTATGAGGGATTGAAACAAGGAGGTGATAGAAGTGACAAAAGAAGAGATTGTGTTTTTATCGTACCTATGAGGGATTGAAACTGTTGCAACTCACGAAGCTGTTTTTGTTCCGGCGTCTCCGTTTTTATCGTACCTATGAGGGATTGAAACTTCAACCCCCCGATGTCGGTGATCGCCACCGTTTTGTGTTTTTATCGTACCTATGAGGGATTGAAACTGAAAATGTGTCCTATTTATCCCGTGATGTAGGTAAAGTTTTTATCGTACCTATGAGGGATTGAAACGCGCAAGAGCCGCTAGCGGCGCAACCGAGCAGCTACGTTTTTATCGTACCTATGAGGGATTGAAACAACTCCTTCGCCATTTCTTTCAGCGATCGGGACAATGTTTTTATCGTACCTATGAGGGATTGAAACACAAGCATGCGTATCAAAAGGTGGCGGCGGTTCCGTTGGGTTTTTATCGTACCTATGAGGGATTGAAACCTGTTTGATAATAGAAGCGTCTTGGCTATCATCCAGTTTTTATCGTACCTATGAGGGATTGAAACCATTCCAGATGGATGATGTTAGCGATCGGATGCCGGTTTTTATCGTACCTATGAGGGATTGAAACGGACGGTACTACCGTCAGAAGGATGGCGAGATCTAGTTTTTATCGTACCTATGAGGGATTGAAACTCAGCCCGCCGTGCTCGGCAAGCTGTTCTACGTATTCGTTTTTATCGTACCTATGAGGGATTGAAACATAATTGGAAAAGCTCGATTGCCAACGCGGCATTAGTTTTTATCGTACCTATGAGGGATTGAAACTGTCGTCGCGATTGGGGATGTCATTATCGATGCGCGGGTTTTTATCGTACCTATGAGGGATTGAAACACGCTCCCGGATCGCGAGGATCTCGGGGGCGTCAAGGTTTTTATCGTACCTATGAGGGATTGAAACAACGCCTTTGCCGCCGTTAGCATATATTTTGCATCAGTTTTTATCGTGCCTATGAGGGATTGAAACTTCCAATTTTTTTCATTCTACATTCCTCCTTAGTTGTTTTTATCGTACCTATGAGGGATTGAAACGCTTGTTTCTCACTCATCTGATCTGTACTCCTTTCGTTTTTATCGTACCTATGAGGGATTGAAACTCGTACACGATCACGTGTACGTCGAGGCGCCAAACCTGTTTTTATCGTACCTATGAGGGATTGAAACTCCCCTCGCCGACGATCAAGTCGGGCGGGAAATCGGTTTTTATCGTACCTATGAGGGATTGAAACCTGCAAGATGATATCACACAGCCGGGGCGGAAGCTGTGTTTTTATCGTACCTATGAGGGATTGAAAC

>NC_014915|3|3|363492-366113|PILER-CR
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAAGTACCAAAAGTGGCTTTTGGATTTCAACACGATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATCGGAGCAACGTCCCGCCCGATGTCGCCGACGTCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TATTCGATTTCGATAAGCCCGCTGGCTTCGAGTATTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCATCGAATCATTCGCTCACCTCCGCAGTCCTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGTCGACTATGCGGAAGCCAATCGCGGGCAGGCGCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGGTACTGCGCGCGAATCCGCTGGCATTAGCCATTACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATATGCCAGTTTGATTTTGTTAAACACCGTTTCAATGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACATGGTGGCGTCCAGCCTCGCCGGCCAGCGATAAAGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATTTTTCTAATTACTTTAGTATCATTTACTATTTTTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCTGCCGTTCCACTCACCGCCGTTTCGCTCACCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGGTATCGGTAGTAATACTCGCGCGCCGCAAAATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGAAGATGAGCAGATAGCTGATAGCGTCATATTGAACA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCAGACGGGGACAGACGTATCAGAACATTGCTTGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATAACCCTGACCCCTTTCTGCCGCAGCAGAGCGATGAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCTCAAGCGCAATCAATTTCCATTTGCGGCTTTCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAAATCGGCGGAGTTTGGAGGAGTTTGGCGTGAAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAGACGACCGTTTCGTCAAAACAGGCAGCCTCCCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAACGGAGTATCTTGATAAGCTCGAAGAAAAAAACT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TAATTGAGGTGAAACGAATGGAGAGGCTCGATGTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGGAGGTGATAGAAGTGACAAAAGAAGAGATTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGTTGCAACTCACGAAGCTGTTTTTGTTCCGGCGTCTCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCAACCCCCCGATGTCGGTGATCGCCACCGTTTTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGAAAATGTGTCCTATTTATCCCGTGATGTAGGTAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCGCAAGAGCCGCTAGCGGCGCAACCGAGCAGCTAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AACTCCTTCGCCATTTCTTTCAGCGATCGGGACAAT
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACAAGCATGCGTATCAAAAGGTGGCGGCGGTTCCGTTGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTGTTTGATAATAGAAGCGTCTTGGCTATCATCCA
GTTTTTATCGTACCTATGAGGGATTGAAAC	CATTCCAGATGGATGATGTTAGCGATCGGATGCCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGACGGTACTACCGTCAGAAGGATGGCGAGATCTA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCAGCCCGCCGTGCTCGGCAAGCTGTTCTACGTATTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATAATTGGAAAAGCTCGATTGCCAACGCGGCATTA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGTCGTCGCGATTGGGGATGTCATTATCGATGCGCGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACGCTCCCGGATCGCGAGGATCTCGGGGGCGTCAAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AACGCCTTTGCCGCCGTTAGCATATATTTTGCATCA
GTTTTTATCGTGCCTATGAGGGATTGAAAC	TTCCAATTTTTTTCATTCTACATTCCTCCTTAGTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCTTGTTTCTCACTCATCTGATCTGTACTCCTTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGTACACGATCACGTGTACGTCGAGGCGCCAAACCT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCTCGCCGACGATCAAGTCGGGCGGGAAATCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTGCAAGATGATATCACACAGCCGGGGCGGAAGCTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC

>NC_014915|3|3|363492-366113|CRISPRCasFinder
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAAGTACCAAAAGTGGCTTTTGGATTTCAACACGATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATCGGAGCAACGTCCCGCCCGATGTCGCCGACGTCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TATTCGATTTCGATAAGCCCGCTGGCTTCGAGTATTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCATCGAATCATTCGCTCACCTCCGCAGTCCTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGTCGACTATGCGGAAGCCAATCGCGGGCAGGCGCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGGTACTGCGCGCGAATCCGCTGGCATTAGCCATTACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATATGCCAGTTTGATTTTGTTAAACACCGTTTCAATGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACATGGTGGCGTCCAGCCTCGCCGGCCAGCGATAAAGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATTTTTCTAATTACTTTAGTATCATTTACTATTTTTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCTGCCGTTCCACTCACCGCCGTTTCGCTCACCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGGTATCGGTAGTAATACTCGCGCGCCGCAAAATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGAAGATGAGCAGATAGCTGATAGCGTCATATTGAACA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCAGACGGGGACAGACGTATCAGAACATTGCTTGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATAACCCTGACCCCTTTCTGCCGCAGCAGAGCGATGAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCTCAAGCGCAATCAATTTCCATTTGCGGCTTTCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAAATCGGCGGAGTTTGGAGGAGTTTGGCGTGAAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAGACGACCGTTTCGTCAAAACAGGCAGCCTCCCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAACGGAGTATCTTGATAAGCTCGAAGAAAAAAACT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TAATTGAGGTGAAACGAATGGAGAGGCTCGATGTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGGAGGTGATAGAAGTGACAAAAGAAGAGATTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGTTGCAACTCACGAAGCTGTTTTTGTTCCGGCGTCTCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCAACCCCCCGATGTCGGTGATCGCCACCGTTTTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGAAAATGTGTCCTATTTATCCCGTGATGTAGGTAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCGCAAGAGCCGCTAGCGGCGCAACCGAGCAGCTAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AACTCCTTCGCCATTTCTTTCAGCGATCGGGACAAT
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACAAGCATGCGTATCAAAAGGTGGCGGCGGTTCCGTTGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTGTTTGATAATAGAAGCGTCTTGGCTATCATCCA
GTTTTTATCGTACCTATGAGGGATTGAAAC	CATTCCAGATGGATGATGTTAGCGATCGGATGCCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGACGGTACTACCGTCAGAAGGATGGCGAGATCTA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCAGCCCGCCGTGCTCGGCAAGCTGTTCTACGTATTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATAATTGGAAAAGCTCGATTGCCAACGCGGCATTA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGTCGTCGCGATTGGGGATGTCATTATCGATGCGCGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACGCTCCCGGATCGCGAGGATCTCGGGGGCGTCAAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AACGCCTTTGCCGCCGTTAGCATATATTTTGCATCA
GTTTTTATCGTGCCTATGAGGGATTGAAAC	TTCCAATTTTTTTCATTCTACATTCCTCCTTAGTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCTTGTTTCTCACTCATCTGATCTGTACTCCTTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGTACACGATCACGTGTACGTCGAGGCGCCAAACCT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCTCGCCGACGATCAAGTCGGGCGGGAAATCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTGCAAGATGATATCACACAGCCGGGGCGGAAGCTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC

>NC_014915|3|3|363492-366113|CRT
GTTTTTATCGTACCTATGAGGGATTGAAAC	CCAAGTACCAAAAGTGGCTTTTGGATTTCAACACGATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATCGGAGCAACGTCCCGCCCGATGTCGCCGACGTCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TATTCGATTTCGATAAGCCCGCTGGCTTCGAGTATTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCATCGAATCATTCGCTCACCTCCGCAGTCCTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGTCGACTATGCGGAAGCCAATCGCGGGCAGGCGCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGGTACTGCGCGCGAATCCGCTGGCATTAGCCATTACC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATATGCCAGTTTGATTTTGTTAAACACCGTTTCAATGC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACATGGTGGCGTCCAGCCTCGCCGGCCAGCGATAAAGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATTTTTCTAATTACTTTAGTATCATTTACTATTTTTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCTGCCGTTCCACTCACCGCCGTTTCGCTCACCTGCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGGTATCGGTAGTAATACTCGCGCGCCGCAAAATC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGAAGATGAGCAGATAGCTGATAGCGTCATATTGAACA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCAGACGGGGACAGACGTATCAGAACATTGCTTGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATAACCCTGACCCCTTTCTGCCGCAGCAGAGCGATGAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCTCAAGCGCAATCAATTTCCATTTGCGGCTTTCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAAATCGGCGGAGTTTGGAGGAGTTTGGCGTGAAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAAGACGACCGTTTCGTCAAAACAGGCAGCCTCCCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAACGGAGTATCTTGATAAGCTCGAAGAAAAAAACT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TAATTGAGGTGAAACGAATGGAGAGGCTCGATGTGA
GTTTTTATCGTACCTATGAGGGATTGAAAC	AAGGAGGTGATAGAAGTGACAAAAGAAGAGATTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGTTGCAACTCACGAAGCTGTTTTTGTTCCGGCGTCTCC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TTCAACCCCCCGATGTCGGTGATCGCCACCGTTTTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGAAAATGTGTCCTATTTATCCCGTGATGTAGGTAAA
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCGCAAGAGCCGCTAGCGGCGCAACCGAGCAGCTAC
GTTTTTATCGTACCTATGAGGGATTGAAAC	AACTCCTTCGCCATTTCTTTCAGCGATCGGGACAAT
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACAAGCATGCGTATCAAAAGGTGGCGGCGGTTCCGTTGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTGTTTGATAATAGAAGCGTCTTGGCTATCATCCA
GTTTTTATCGTACCTATGAGGGATTGAAAC	CATTCCAGATGGATGATGTTAGCGATCGGATGCCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	GGACGGTACTACCGTCAGAAGGATGGCGAGATCTA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCAGCCCGCCGTGCTCGGCAAGCTGTTCTACGTATTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	ATAATTGGAAAAGCTCGATTGCCAACGCGGCATTA
GTTTTTATCGTACCTATGAGGGATTGAAAC	TGTCGTCGCGATTGGGGATGTCATTATCGATGCGCGG
GTTTTTATCGTACCTATGAGGGATTGAAAC	ACGCTCCCGGATCGCGAGGATCTCGGGGGCGTCAAG
GTTTTTATCGTACCTATGAGGGATTGAAAC	AACGCCTTTGCCGCCGTTAGCATATATTTTGCATCA
GTTTTTATCGTGCCTATGAGGGATTGAAAC	TTCCAATTTTTTTCATTCTACATTCCTCCTTAGTT
GTTTTTATCGTACCTATGAGGGATTGAAAC	GCTTGTTTCTCACTCATCTGATCTGTACTCCTTTC
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCGTACACGATCACGTGTACGTCGAGGCGCCAAACCT
GTTTTTATCGTACCTATGAGGGATTGAAAC	TCCCCTCGCCGACGATCAAGTCGGGCGGGAAATCG
GTTTTTATCGTACCTATGAGGGATTGAAAC	CTGCAAGATGATATCACACAGCCGGGGCGGAAGCTGT
GTTTTTATCGTACCTATGAGGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014915.1\|WP_013522875.1\|357771_358902_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	pfam09700_cmr3gr5_CAS-III-B	gnl\|CDD\|187879
NC_014915.1\|WP_013522874.1\|356131_357772_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl\|CDD\|187810
NC_014915.1\|WP_013522882.1\|369389_370622_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NC_014915.1\|WP_013522885.1\|372290_372719_+\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013522880.1\|366369_367413_+\|P1-family-peptidase	unknown	unknown	gnl\|CDD\|239071
NC_014915.1\|WP_013522876.1\|358901_359795_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl\|CDD\|274210
NC_014915.1\|WP_013522883.1\|371022_371676_-\|PspA/IM30-family-protein	unknown	unknown	gnl\|CDD\|224755
NC_014915.1\|WP_013522887.1\|373866_374277_+\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013522872.1\|353886_355227_+\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09732_csx1_CAS-III	gnl\|CDD\|378186
NC_014915.1\|WP_013522870.1\|348778_349525_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_014915.1\|WP_013522891.1\|377973_379347_-\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|380161
NC_014915.1\|WP_013522878.1\|360229_361378_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	COG1604_cmr6gr7_CAS-III-B	gnl\|CDD\|187792
NC_014915.1\|WP_013522884.1\|371635_372157_-\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013522889.1\|374666_376976_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|224428
NC_014915.1\|WP_041469329.1\|361609_363277_-\|IS1634-family-transposase	unknown	unknown	gnl\|CDD\|227708
NC_014915.1\|WP_013522881.1\|367495_368758_-\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_014915.1\|WP_013522871.1\|352687_353884_+\|CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl\|CDD\|187873
NC_014915.1\|WP_013522877.1\|359808_360216_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	gnl\|CDD\|378242
NC_014915.1\|WP_013522886.1\|372809_373511_-\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013522873.1\|355226_356135_+\|CRISPR-associated-protein	unknown	unknown	gnl\|CDD\|273859

Protein	Function_ID	Function_description	E-value
NC_014915.1\|WP_013522875.1\|357771_358902_+\|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	1.50055e-45
NC_014915.1\|WP_013522874.1\|356131_357772_+\|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl\|CDD\|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	3.29957e-77
NC_014915.1\|WP_013522882.1\|369389_370622_-\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.87391e-108
NC_014915.1\|WP_013522891.1\|377973_379347_-\|GHKL-domain-containing-protein	gnl\|CDD\|380161	NF033092, HK_WalK, cell wall metabolism sensor histidine kinase WalK. This model describes WalK as found in Staphylococcus aureus (sp\|Q2G2U4.1\|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.	2.14341e-70
NC_014915.1\|WP_013522880.1\|366369_367413_+\|P1-family-peptidase	gnl\|CDD\|239071	cd02253, DmpA, L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active heterodimeric form. The cleavage results in two polypeptide chains, with one chain containing an N-terminal nucleophile. This group represents one of the rare aminopeptidases that are not metalloenzymes. DmpA shows similarity in catalytic mechanism to N-terminal nucleophile (Ntn) hydrolases, which are enzymes that catalyze the cleavage of amide bonds through the nucleophilic attack of the side chain of an N-terminal serine, threonine, or cysteine.	5.15513e-169
NC_014915.1\|WP_013522876.1\|358901_359795_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	8.03044e-72
NC_014915.1\|WP_013522883.1\|371022_371676_-\|PspA/IM30-family-protein	gnl\|CDD\|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	2.99646e-23
NC_014915.1\|WP_013522872.1\|353886_355227_+\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|378186	pfam09455, Cas_DxTHG, CRISPR-associated (Cas) DxTHG family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. The family describes Cas proteins of about 400 residues that include the motif [VIL]-D-x-[ST]-H-[GS]. The CRISPR and associated proteins are thought to be involved in the evolution of host resistance. The exact molecular function of this family is currently unknown.	8.05541e-64
NC_014915.1\|WP_013522870.1\|348778_349525_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	1.34584e-34
NC_014915.1\|WP_013522878.1\|360229_361378_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl\|CDD\|187792	cd09661, Cmr6_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	2.20342e-38
NC_014915.1\|WP_013522889.1\|374666_376976_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	6.72728e-151
NC_014915.1\|WP_041469329.1\|361609_363277_-\|IS1634-family-transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	2.34312e-27
NC_014915.1\|WP_013522881.1\|367495_368758_-\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	0
NC_014915.1\|WP_013522871.1\|352687_353884_+\|CRISPR-associated-protein	gnl\|CDD\|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	1.96696e-15
NC_014915.1\|WP_013522877.1\|359808_360216_+\|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl\|CDD\|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	3.82008e-35
NC_014915.1\|WP_013522873.1\|355226_356135_+\|CRISPR-associated-protein	gnl\|CDD\|273859	TIGR01894, hypothetical_protein, CRISPR type III-B/RAMP module RAMP protein Cmr1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model represents the region of stongest conservation, the N-terminal half, of one such family, represented by TM1795 from Thermotoga maritima. This protein is the first of a set of six genes, mostly from the RAMP superfamily, that we designated the CRISPR-associated RAMP module.	1.82179e-06

>NC_014915.1|WP_041469329.1|361609_363277_-|IS1634-family-transposase
MYIRRVTRKNKDGTTVAYLQLAHNEWDPKAKYAKAKVIYSFGREDEVDRAVLERLAKSISRFLSPEQAWEIETLTGEVSDDFQFQSSKRLGGAWLLDQLWRQLGLGEILHSLFASRHHQIPLERLIFAMVANRALHPSSKLAMEEWVEKDVHIPHLPQVASHQLYRAMDELLAVQPELERQVFHAVADLLNLEVDLIYFDTTSSYFEVDPSETPEGESLRKQGFSKDKRPDLVQIVIGLAVTREGVPIRAWVWPGNTMDMTVIKQVKQDLIGWKLGRVISVMDRGFSSEENLRILQQAGGHYIVGEKMRSGKAAVEEALNRRGRYQQVRENLHIKEIIVGDGEARQRYVLVYNPSEAERQRKEREKLLESLKEELEGLRQLPNEAHHKATCRLRSHPSYGKYLRQLKDGTLRIDKQAVREAEKYDGKYLIRTSDDTLSAEDVALGYKQLVDIEQAFRTLKSTLELRPMYHRLEDRIRAHVLLSWLALLLVRIVEIRTHESWPKVRDECERLMLGHFSSKNGDLYQRTELTAKQAQFFAALGLEPPPKILGIHPRA
>NC_014915.1|WP_013522878.1|360229_361378_+|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MLFHPKDTREVMQRANKSAAHLAYHLHYFLEHQWNDKKRVWEPSKRLKPVPILPELKEIGEQLQAQREQAMIEWAQTGYVKKLKARLVGRIIHGLGAGHIRETSLTIHPVYGLPYIPASSVKGLVRHWFIEAYCEGEEKQLNEHEIGREIFGTQGNKGIVQFHDIFLIEGLQLTGDVLAVHMKEYYEGNRAATDDQKPVPVSFWTVMATEVDIYLTANRSAPQNDEETVRLLEAAALWTQQALTEWGIGSKTSSGYGRFAEVYDVTEMEFLPIVQKEQVRLEQQKKEREMLEQRKREEEEKARLALLSPEERLVVEIERLTDSQTDEQRSKDVLYQQVIEQRNRQAALALQAYWQRIGQWGKSVSKKQKQKIDKLQQLLNDE
>NC_014915.1|WP_013522877.1|359808_360216_+|type-III-B-CRISPR-module-associated-protein-Cmr5
MGTKVQRVGIENGRAAFAFQEVKQAKEGLKENFENYRSYVKKMPSLIQVNGLGQALAFCFQKKGREYRSIYRSIAKWMKEQFPGQFGKEDMELVEVVVNLSSADYRLWTMETLALLDWMRKFADGMVKDDAEAAK
>NC_014915.1|WP_013522876.1|358901_359795_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYSIIRPFLLHAVTSVHAGSGSEIGLVDLPIQREKHTGFPKIESSSLKGALRYHMTQALPDETNKLELIFGADKGQESVTQASAIALSDARVLLFPVKSLRGVFAWITCPHVLERWNQEMSVHQEMKGKGEGFQPLPVPGPNTVSADRLIVADGRIILEEYTFPVTVSPEAKQLAEQLSAIIGESSRLRVTDRLVILSDDDFTDFVKLSTEVNARIRISPETGTVDSGALWYEENVPPETFFYSFLYIGHVRGKGVDGLATAEEIERYLVDERKFPSVFQLGGNSTLGRGMMRTIWL
>NC_014915.1|WP_013522875.1|357771_358902_+|type-III-B-CRISPR-module-associated-protein-Cmr3
MTKLVLTPADTFFFKNHHATQAGETTVMESMFPPRPNTIYGALRAAYIYAYSSFDEFARGADERVKLWMGTPDERGAFRLHYCALADGDSLFLPLPLDYQVVEEGDSLKAYPLQLAKDRKPSSASTMWRLASSRREKTKSSQHRYVSLSEWKKALLLNQPIASLRTLSSFIVQEEKVGIQLDVSRRTAQEGFLYRVGKHRFLGDSSLVAYIDDGPDFSNVKWARIGGENRPWFIRQHPEEFRLWNDDEKRRIEQDIQRTKMAKIIFLSPAIFANGSRPAAMEGDRWTWPNGAVVTWLAAAIGRPELYGGWDIVRHRPKPRKWMIPAGSVIYVKIERDDDLRLVFSALDGIHLTDEGAEEGFGFAVLASVHESEEEL
>NC_014915.1|WP_013522874.1|356131_357772_+|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MTNRYVVIFTVGPVQSFIASARKTEDFWSGSYILSHLVREAIKRFYQFDANCEMIYPLVTEKELRSPSQRDVHIASIPNRLTVIMEGTEEEVCGWLREAEQDVCNVFLDFCFQAVRRVFPHLTDHEQELLERMVEQQVRSFLEIYWVAEPYEPSMSFREVRERAERRLGALKNEKHYIPVSQQGLVCSVCKEREALRLEEIGEFDHYGEIKKKTMSLWQRRAVKFQGTGGDEEDDRRAGRIKDNEFLCGICLGKRAARDYFADLFGTSFPSFPSVLDIGQGDYYAVLLMDGDDMGKWFSGERKDEYSRTSQKLARFAKETVPWIVQERCKGKLVYAGGDDVLAFVPVETALKAAEMLRLAFADERQGLGSGATASFGVVIAHKKAPLQHVLNAARALEQKAKRYYNDKTAQRKDALALAVHTRSGEISEAVLPWIVGEKMVSKLLEEWLGLLKTSLSPNFIFHFASAFAPLLHEKDCPKWENRDMLATELRRLLRRSVKEGSCLDAQDIARYTSTLLVLHEAVRSSYDFLHLLKMLTFFKRSKGRG
>NC_014915.1|WP_013522873.1|355226_356135_+|CRISPR-associated-protein
MTYQDRSGATAVVQSSYQLVLLTPAAIHGADPREKAEFRLSSLRGVWRYWWRTLQDEPDPEKLLAKEEEWFGGTRKMKQQSPIHLSMAGVMEGTKKENILPHRTSPTLVPALPAGGEVTVTLSVRKRHQERLAQYDWYFQYVLHLASFGQRSRRGFGAVQWIGHQWSNVGEYVESLRMVLEHIGVAGAFSFAERDCLVARRGDIQTQHPVLSAVWIGEGKESAAEVVKAFGKASHEANRYGSLGYMRGKAGKLSSPLWCTVRKIGNWYYPIVTEVRNHDPHYSEPRYEQDRNRFLEIVGVRI
>NC_014915.1|WP_013522872.1|353886_355227_+|TIGR02221-family-CRISPR-associated-protein
MGRRVLLSFLGLGDYEYCYYTYEGKTSTYTRFIQTAVYELFRNDEPMDVVVFATKEAQDRNGQDRKKGDKLLEGIGTAFSRIAPEANVKIVEIESGQDEQANWRLFDRIMDEIKEGDTIYFDITHSFRSIPFVALIVLNYARLVKKADIGAIIYGWFEVLGRPIDVEQMPEEQRVAPIVNLTSMAKLLDWTNGVDQFLRTGDASIIQALTAKENSEVFRNPSLSQAVKDEVKELRELTKRLDQTEKAIRTCRSLQIDEEVQKFHEQLGRVRSASAEAIKPLVPLLDVMEKKYAMFDDDPIMNSWKAVRWCLDHGLIQQALTMLEENAVTAVCRVLGLDLRNEKARGDVHSAIEILLRDIPKEEWRVRSVERVEQIIDFLSPYKGDLKRFSTLKERRNDINHAGARPQPLKAEKFWPDAEQSFRELGAFFERMSALAKSMQTVKGNG
>NC_014915.1|WP_013522871.1|352687_353884_+|CRISPR-associated-protein
MYQHIVVTCGVSLFGNRNIFSMNRDETMGEIRPWLSSRNIDEEKQEKIDQWIRHARQFAHEATRDPNRVSAEYSMIYELRRQGKLAERPTVVLIVTETVGGRIVEAILTRLLEEDFQANVRIIYVDVDVNHPRRMQETLGEYMWKVASALSHGEPSTTCFAPIGGYKVMTSLGYIVGAFLHYPTAYMHEDGQVLHEIPPVPIHMDEQFVHEHFDLLRKCQRDLVNAASLSYHEKQCILRYPFLFQQEEGFVYLSAFGQFLLEHEKYKHLFGTTFFASDQVSDMLRHNHHQSLFVHQQLKELVKKLKHKEGDVAVLYHEKSFKTIDTRKVKYHLYKGASNGQTAFRLAYRYDEKEDCLYANYLWLDHNRYEREAAKGKGIYEDNSPFVDMTKQLVGMGR
>NC_014915.1|WP_013522870.1|348778_349525_+|CRISPR-associated-endoribonuclease-Cas6
MRLTVTMSGRQGTVSLPLHYQHLLQGLLYRSLENEQLAAFLHDRGFRHGKRSFKLFTFSRLFGTHQVNRERKTIHFLGDFQWHIDTALLELTQQLGQRFLVQREIELYGQLIEVKSVKMESVDIRGHEIDVVMLSPLTVYSTYETMDGRKKTQFFDPDDEVFPHLIELNFCHKYAAYYGVPPAERLSIQPIYVHRRHRVVTLFKDMYITGWMGHYRLCSSPEQLTFLYHVGLGSRNSQGFGMFRLASG
>NC_014915.1|WP_013522880.1|366369_367413_+|P1-family-peptidase
MRSKLRHLGFSIGTLPTGERNQITDVPGVKVGHVTIREDMDERTVIRTGVTAVLPHGGNWFLEKVPAACFVLNGFGKTVGLVQVEELGAIESPIMLTNTFSVGAVWQGTLEHMLAMTPEIGDTTGSVNIVVGECNDSYLNTARALSVTKEHAKQAIAEARVDMEEGAVGAGTGMMCFGWKGGIGSSSRIAGGMYTVGALVVSNFGRREELRLVPYVPPSFDERDVPPGSIMMIVATDAPLDARQLKRAAVGLARTGSHVHHGSGDIVIAFSNAYMIPHFADSSHQPLPPLVRDDAPLMNELFQAAIEAVEEAIWNSLTMAETTTGRNGRVGEAIPYSLLRWIKWTEK
>NC_014915.1|WP_013522881.1|367495_368758_-|group-II-intron-reverse-transcriptase/maturase
MALLERILARDNLITALKRVEANQGAPGIDGVSTDQLRDYIRAHWSTIRAQLLAGTYRPAPVRRVEIPKPGGGTRQLGIPTVVDRLIQQAILQELTPIFDPDFSPSSFGFRPGRNAHDAVRQAQGYIQEGYRYVVDMDLEKFFDRVNHDILMSRVARKVKDKRVLKLIRAYLQAGVMIEGVKVQTEEGTPQGGPLSPLLANILLDDLDKELEKRGLKFCRYADDCNIYVKSLRAGQRVKQSIQRFLEKTLKLKVNEEKSAVDRPWKRAFLGFSFTPERKARIRLAPRSIQRLKQRIRQLTNPNWSISMPERIHRVNQYVMGWIGYFRLVETPSVLQTIEGWIRRRLRLCQWLQWKRVRTRIRELRALGLKETAVMEIANTRKGAWRTTKTPQLHQALGKTYWTAQGLKSLTQRYFELRQG
>NC_014915.1|WP_013522882.1|369389_370622_-|MFS-transporter
MNWKRSVRVLWLCNFMVSAGMTMVIPFLSLLLWEMGVTERHSLSVWTGLVFSATFLSAAVMAPIWGMFADKYGQRANLIRAGIGMGLITGFMAFAASPMALLTLRFLVGFFSGFITVSFSYLARVVPKDHSGEALGALQTGSIAGNIIGPLIGGALSDLFGFRPVFLVTGFCILATLLPVIFWLEKDPVAPQTKEHHASFKEVFAHRPLVILFVATFLVQIAALGVNSMMTIFVQSLVGHSRNLAFLSGLASSITGIATIIGAPYLGKLGDRIGQANMLPMLLVLSGLFALPQVWTDHLYELYVWRFLQGLVVGGVWPSIQALINAQSPRRIQGRVFGVTASSRFLGNLTGPTAAGAIAGFFSISSIFALSGLLLIATGALVGHATHDRAWREEIKEKIAAWTHRLHSRH
>NC_014915.1|WP_013522883.1|371022_371676_-|PspA/IM30-family-protein
MGMFRRMKTIVLAKVNEQIDQWEDPIAMTKQYLRDLEEQLAQGRQALAGQWVAERRYETLITQAEATIEKRSRQAKLALERNEEAVAKLALRDKLLYEKKLEAYKQQYDAIKAKTAEVANRLNQLCERYDELSAKQLELAARVNAAQALKQIDSALASFSADEALRGFARMEERVMALEAEAAAARFGTNAALSPVPFDEEVERELAKWKEAQANNA
>NC_014915.1|WP_013522884.1|371635_372157_-|hypothetical-protein
MKKARAVFLLALVALAGVSLFHVLTPHEVMAHGRPGAMFDGMHGGFGHHRPEFGMGPRGGWMMAGLLMWLIPLLLVGAGAIWLAAARSKRWIGWALVALGVVALLPKWVLVLLALAAVYALGRRQARKPAAAKVWMPAPPSVSVDWLDEWEKSIQKEANQHGHVSPNEDNRSR
>NC_014915.1|WP_013522885.1|372290_372719_+|hypothetical-protein
MDEDFHLTCGEEREDVVRSYGLDVGGALLVLLFSFLFPTFNVGYYAYGSFLGFAIGSLIVGLARIRWNPHARLGGVLVGSFLIIAVSVIIIRLFPIEIRDVGDVVMPYVNAIVNALIYFMITNALHLLHRLTQGNDSFWKKR
>NC_014915.1|WP_013522886.1|372809_373511_-|hypothetical-protein
MRRFSFCFLSSVFLLVIALFSPTSRVGAEQFIQNKVKLKNVFVDIHYDKSQVNLVRTEDQNSTKISLVDKKSGKILETYGEIIQPLEQVATKTVGMNDASVANTSGTYSISTVYRERNDGPAVSRLSTQLYIYSYDSFRQINKVLNTWWSEASGGSWYLTRDVANTVSMTGSFPTTKVQTSGSATIEVKTSYSITGSFSISALKEAGFTYGYSSGSDIYYRKPINLGFVYSLY
>NC_014915.1|WP_013522887.1|373866_374277_+|hypothetical-protein
MRKLYGLLSILLLCVCGAVIFFQTSAKTHFNRKEVEVIRVTSRMEDFSSIHEIRDKRKVNRIMEIIKFVEWSKTAKVDEGQPDYRFWLEHPKTKDRLFNYNIWFKKNNTIIFDKKTGKYGVVPSKYETELKSLLNE
>NC_014915.1|WP_013522889.1|374666_376976_-|YhgE/Pip-domain-containing-protein
MHAFQLWMQELKAVTSNRKVLIPIMAVLFIPLLYSGMFLWAFWDPYDHLDELPVAVVNKDKGTTFEGKEFHLGDDLVEKLKEKKQFDWHFVNEREGEKGLKEQKYYMLIQIPEDFSQNATTLQDDHPKKLQLIYKPNEGFNFLSAQIGGTAVEKIKTEVAKTLTETYAENMFENIQTLADGLTKASDGAKQLHDGLGEAKNGTNKLYDGMKKAQDGSKDLHHHLATLAEKSIAFTDGLHQAANGSAQVQTGVQMLDNGMKHMVDGQGQLLDGAKQVQEGTANLALGAKRVYEGMQALDARMPQLLQGSEQLSVGAEKLASSLAQWQQGAAQVQTGATQVTGGLERLAAQLDALIAQTPDPTQKAVYEQLKENVVKLSLGSKQIENGIAQLNDGTKALQSGAASLSGGAKQLHEGHIALDQGVNKLLSGQQQLVNGANALANGQEKLVAGMNTLHEKMKEAEQGADKLANGGQTLTSGLQVLAQGADRLQDGAHQLANGSQQLASGMNELTSGTRDLQDGMNRLTDGSEELADKLKEGAKKASDVKANEDVYDMFAEPVKVKNEKVNEVPNYGTGFTPYFLSLGLFVGALLLSIVFPLREPAGVPRSPFHWFFAKFGVLIGVGILQALLADSVLLYGLDLQVKSVPFFILFSVVTSITFLSVIQFLVTTFGDPGRFIGIVVLILQLTTSAGTFPLELIPRSLQHFNAWLPMTYSVFGFKAVISSGDFSFMWENIGKLLLFIVAMMVGTMAYFTMQHRRQFATAVEQASEA
>NC_014915.1|WP_013522891.1|377973_379347_-|GHKL-domain-containing-protein
MINRWNEWRDWLRRLGSADLFRRAHWRLTALYSGIFTLFLALFIMIAAALFYWITTSDQERRITRLAEQEANTIEQFLLKQSDFDLFHDESVVLLSEDQLFFYVIGPNGDLLAGDEIHPRLRPYFLNVLSRMDTGERTPVYVTVSLPEHMPGLARAAARDWRVLAVAHPLIIHGDFAGMLYIGMDVTSFFGVFHWLLIVLIGLAVLFLAVGVALSYFMSKRALIPIEEAYERQRQFVADASHELRTPLSVVFSSVEALALEEDVMKNDFARRLLDRLREELKRITKLIGDLLTLARVDAKHAALELSKQTFDFRPHAERTFQLVSELAAKKQITMHFHAPEQAIVTADPDKLTQLLYILLDNAIKYTPEGGDVTLSIRTEPKQFILSVKDTGIGIPPEDIGRIFDRFYRVDKTRSRQQGGHGLGLSIAKWIVDAHGGAIHVQSQLGQGSEFLVRLPV

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Crispr_ID: NC_014915_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014915_4

1337850-1337948

Orphan

Consensus_repeat	Method
AACCAAACAAAAAGGAGACATGAACCAGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014915_4

>merge|NC_014915|4|1337850-1337948|CRISPRCasFinder
AACCAAACAAAAAGGAGACATGAACCAGACCAGGATGCCGCATTGAGCGGGTCGAATACCGAGAGGAGTAACCAAACAAAAAGGAGACATGAACCAGAC

>NC_014915|4|4|1337850-1337948|CRISPRCasFinder
AACCAAACAAAAAGGAGACATGAACCAGAC	CAGGATGCCGCATTGAGCGGGTCGAATACCGAGAGGAGT
AACCAAACAAAAAGGAGACATGAACCAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014915.1\|WP_013523486.1\|1333541_1335221_+\|DUF3578-domain-containing-protein	unknown	unknown	gnl\|CDD\|371900
NC_014915.1\|WP_013523490.1\|1342935_1343760_+\|DUF4391-domain-containing-protein	unknown	unknown	gnl\|CDD\|379562
NC_014915.1\|WP_015731688.1\|1327955_1329122_+\|SEC-C-domain-containing-protein	unknown	unknown	gnl\|CDD\|235521
NC_014915.1\|WP_013523496.1\|1354018_1354228_+\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013523492.1\|1345660_1348615_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|226115
NC_014915.1\|WP_013523493.1\|1348969_1349488_+\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013523482.1\|1325424_1326366_+\|ribokinase	unknown	unknown	gnl\|CDD\|238916
NC_014915.1\|WP_013523484.1\|1330681_1331218_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225269
NC_014915.1\|WP_013145635.1\|1338947_1339241_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376540
NC_014915.1\|WP_011230871.1\|1327324_1327678_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NC_014915.1\|WP_013523487.1\|1335189_1337691_+\|DUF2357-domain-containing-protein	unknown	unknown	gnl\|CDD\|286861
NC_014915.1\|WP_013523485.1\|1331458_1332226_-\|dioxygenase	unknown	unknown	gnl\|CDD\|153375
NC_014915.1\|WP_013523491.1\|1343710_1345657_+\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|225100
NC_014915.1\|WP_013145641.1\|1329552_1330713_+\|ImmA/IrrE-family-metallo-endopeptidase	unknown	unknown	gnl\|CDD\|225412
NC_014915.1\|WP_013523481.1\|1324019_1325243_+\|YeeE/YedE-family-protein	unknown	unknown	gnl\|CDD\|377230
NC_014915.1\|WP_012820563.1\|1349758_1351039_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_014915.1\|WP_013145643.1\|1326365_1327271_+\|pseudouridine-5'-phosphate-glycosidase	unknown	unknown	gnl\|CDD\|377251
NC_014915.1\|WP_013523495.1\|1352494_1353799_-\|acetamidase/formamidase-family-protein	unknown	unknown	gnl\|CDD\|376984
NC_014915.1\|WP_013523489.1\|1339684_1342930_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|197304
NC_014915.1\|WP_013523494.1\|1351434_1352424_+\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|226612

Protein	Function_ID	Function_description	E-value
NC_014915.1\|WP_013523486.1\|1333541_1335221_+\|DUF3578-domain-containing-protein	gnl\|CDD\|371900	pfam12102, DUF3578, Domain of unknown function (DUF3578). This presumed domain is functionally uncharacterized. This domain is found in bacteria and archaea. This domain is typically between 177 to 191 amino acids in length.	8.1227e-75
NC_014915.1\|WP_013523490.1\|1342935_1343760_+\|DUF4391-domain-containing-protein	gnl\|CDD\|379562	pfam14335, DUF4391, Domain of unknown function (DUF4391). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 220 and 257 amino acids in length.	4.18982e-47
NC_014915.1\|WP_015731688.1\|1327955_1329122_+\|SEC-C-domain-containing-protein	gnl\|CDD\|235521	PRK05590, PRK05590, hypothetical protein; Provisional.	1.56799e-15
NC_014915.1\|WP_013523492.1\|1345660_1348615_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|226115	COG3587, COG3587, Restriction endonuclease [Defense mechanisms].	0
NC_014915.1\|WP_012820563.1\|1349758_1351039_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	6.98211e-32
NC_014915.1\|WP_013523482.1\|1325424_1326366_+\|ribokinase	gnl\|CDD\|238916	cd01941, YeiC_kinase_like, YeiC-like sugar kinase. Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time.	4.34414e-76
NC_014915.1\|WP_013523484.1\|1330681_1331218_+\|hypothetical-protein	gnl\|CDD\|225269	COG2405, COG2405, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	4.0991e-07
NC_014915.1\|WP_013145635.1\|1338947_1339241_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	7.70653e-17
NC_014915.1\|WP_011230871.1\|1327324_1327678_-\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00738099
NC_014915.1\|WP_013523487.1\|1335189_1337691_+\|DUF2357-domain-containing-protein	gnl\|CDD\|286861	pfam09823, DUF2357, Domain of unknown function (DUF2357). This entry was previously the N terminal portion of DUF524 (pfam04411) before it was split into two. This domain has no known function. It is predicted to adopt an all beta secondary structure pattern followed by mainly alpha-helical structures.	5.76658e-99
NC_014915.1\|WP_013523485.1\|1331458_1332226_-\|dioxygenase	gnl\|CDD\|153375	cd07363, 45_DOPA_Dioxygenase, The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine. This subfamily is composed of plant 4,5-DOPA Dioxygenase, the uncharacterized Escherichia coli protein Jw3007, and similar proteins. 4,5-DOPA Dioxygenase catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine (4,5-DOPA). The reaction results in the opening of the cyclic ring between carbons 4 and 5 and producing an unstable seco-DOPA that rearranges to betalamic acid. 4,5-DOPA Dioxygenase is a key enzyme in the biosynthetic pathway of the plant pigment betalain. Homologs of DODA are present not only in betalain-producing plants but also in bacteria and archaea. This enzyme is a member of the class III extradiol dioxygenase family, a group of enzymes which use a non-heme Fe(II) to cleave aromatic rings between a hydroxylated carbon and an adjacent non-hydroxylated carbon.	5.44699e-107
NC_014915.1\|WP_013523491.1\|1343710_1345657_+\|site-specific-DNA-methyltransferase	gnl\|CDD\|225100	COG2189, COG2189, Adenine specific DNA methylase Mod [DNA replication, recombination, and repair].	8.15449e-34
NC_014915.1\|WP_013145641.1\|1329552_1330713_+\|ImmA/IrrE-family-metallo-endopeptidase	gnl\|CDD\|225412	COG2856, COG2856, Predicted Zn peptidase [Amino acid transport and metabolism].	1.28033e-22
NC_014915.1\|WP_013523481.1\|1324019_1325243_+\|YeeE/YedE-family-protein	gnl\|CDD\|377230	pfam04143, Sulf_transp, Sulphur transport. This is an integral membrane protein. It is predicted to have a function in the transport of sulphur-containing molecules. It contains several conserved glycines and an invariant cysteine that is probably an important functional residue.	9.83977e-56
NC_014915.1\|WP_013145643.1\|1326365_1327271_+\|pseudouridine-5'-phosphate-glycosidase	gnl\|CDD\|377251	pfam04227, Indigoidine_A, Indigoidine synthase A like protein. Indigoidine is a blue pigment synthesized by Erwinia chrysanthemi implicated in pathogenicity and protection from oxidative stress. IdgA is involved in indigoidine biosynthesis, but its specific function is unknown. The recommended name for this protein is now pseudouridine-5'-phosphate glycosidase.	0
NC_014915.1\|WP_013523495.1\|1352494_1353799_-\|acetamidase/formamidase-family-protein	gnl\|CDD\|376984	pfam03069, FmdA_AmdA, Acetamidase/Formamidase family. This family includes amidohydrolases of formamide EC:3.5.1.49 and acetamide. Methylophilus methylotrophus FmdA forms a homotrimer suggesting all the members of this family also do.	4.00767e-60
NC_014915.1\|WP_013523489.1\|1339684_1342930_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|197304	cd10311, PLDc_N_DEXD_c, N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain. N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain. All members of this subfamily are uncharacterized. Other characterized members of the superfamily that have a related domain architecture ( containing a DEAD/DEAH box helicase domain), include the DNA/RNA helicase superfamily II (SF2) and Res-subunit of type III restriction endonucleases. In addition to the helicase-like region, members of this subfamily also contain one copy of the conserved HKD motif (H-x-K-x(4)-D, where x represents any amino acid residue) in the N-terminal putative catalytic domain. The HKD motif characterizes the phospholipase D (PLD, EC 3.1.4.4) superfamily.	6.92314e-58
NC_014915.1\|WP_013523494.1\|1351434_1352424_+\|restriction-endonuclease	gnl\|CDD\|226612	COG4127, COG4127, Uncharacterized conserved protein [Function unknown].	5.1926e-68

>NC_014915.1|WP_013523487.1|1335189_1337691_+|DUF2357-domain-containing-protein
MASLRSGSGRDDYELVHIETKQLTLVIKGKPYHEQYESLQQYRRLDFHETMEFFASGEEVRSVKLFDVDAGELVDWSGGHRPIFFENGVYQLLVVPKTDRVLSFYHESPALRNAISLVDIGGQAVLMGNLHFPNEVGLSTFEIRDGSRSILDVTIEVFPTKLTYKQDYQILLDEVSEEIYNLAFHFIKRTYQRARAKRDGAPSRSEFFRLMEAHIGDFLHAIRHIERQPHHQLSTVHVRVRGDQLGRLDAAGRNDLRKRPQVFRDVKRGIDIGSRTVMPRSGLKAKKELTYDTLENRFVKWMMTRLVEKLLDLFEHVQGKQKRYETEPDPDLLERIQSMIRALENRLRHSFWRPIGRLDRSVMSLVLQMAPGYRDAYQLFLIITRGLALQGKLYRMSVKDVATLYEYWTFLKLGQLLGKKYKLISQNVIQVNRLGLFVNLEKNRSAKRVYEHPYTGERITLTYQPYEGRLPTVPQMPDTVLAIEKKGKDYTFNYIFDAKYRLDFAVSGSSYEKRYGMPGPMEDDINTMHRYRDSLVARRGGPYERTAFGAYVLFPWHDEDSYQEHPLYKSINDVNIGGLPFLPNATRLVEQFIERLIEKNPEELQHEGILPQGIIEEWRSAFDEHVLVGMVPSARHYEVYRKHRFYHIPVKQLKKGWQDARYIALYPKRGAAPQNGVTCFGKIADVNIVKRSAIAELPKRSDEEYVRFEVEHWQPLKNVIRPVGYGIAVYAMTTLNMLKQAKELPELFMKSKDEIALWRLLRRLSDRIRFDLDARYLDQASKITAYRVKNLFIRLEDDRLMITNGTKHKTIPAELLRKQPSAVFREVVGMMGE
>NC_014915.1|WP_013523486.1|1333541_1335221_+|DUF3578-domain-containing-protein
MSLHDLFRQVMAIYEQEKSEKLSKERRSFQLVTRAIPEALKTLPFLPPDRYVVKGSVGQGVWTDVPWVAVMDQEVTDSTQRGYYIVYLFSEDMRRLYLTLAQGVTETPRDEMERVKRDIRQLIPAGERVRTNDDIRLGESKRAKDYERSVAAYIAYSFDDLPSDEQLARDLETMIGYYRQYVERTEPMAPPEQALSYREAVEHIHSYISAKGFYYTKEEVTNLFLSLKTKPFVILSGISGTGKTKIVQWLAESVGATEDNGRFTFIPVRPDWHDGSDLLGYVDIKGDFKPGPLTNVIIEAGKHPDKPYFVVLDEMNLARVEHYFSDVLSVMESRRWEDGRITSSRLLPRETAGCDLVLPPNVYIIGTVNMDETTHPFSKKVLDRANTIEFNRVQLDHLDFLRDLPTVAPLSVGQELFAARYLHLKDVYARCPELVETVTKQLVEINRILAPLGAHIGYRVRDEICFYLAYNEEGKLMEFDKAFDYCLMQKILPRLSGSDMRLETALKQLFVLCAGFEPDGEYGGVLDVSYARYPKSAEKIWQMLRRLEDDGFTSFWLGA
>NC_014915.1|WP_013523485.1|1331458_1332226_-|dioxygenase
MRLPALFLAHGSPMLAIEDNAYTAFLGKLGEGIRPQAVVIFTAHWMTRQPTVSAVEGTYDMIYDFSGFPRELYEVVYPARGSVEWAERVRERLAGVAEVAVDSTRGLDHGSWVLLHRLFPNADIPVVQASVLPWWTPMQLFQLGEALCPLRDEGLMVIGSGGTVHNLMALRWEGHAEADAWAMAFDDWLLSRSAAHSEEVFDYENKAPYAKQAVPTPEHLAPYWIAYGAGDHDQAPRVLFREYQYGSLSLMAVTF
>NC_014915.1|WP_013523484.1|1330681_1331218_+|hypothetical-protein
MDVRKIRGLYKKRAVVDNNVLNDFYELGRMDLLTRVFGRVCVPESILLNETPGDIQKALRQIDYETVSLHTEEGYGLMYQLLTEWTGLSEYDAELIAIAGQDMILCSSNEKRIMNACESYGIEYTGTLGILCCAYEHQLIGREEFKGLIDRLFSDECSCHLHPRLKNQIDKQYHLQDV
>NC_014915.1|WP_013145641.1|1329552_1330713_+|ImmA/IrrE-family-metallo-endopeptidase
MEIKQTIAKNLNRVKNELGLKNQDLAEVMGVTRQTIAKYLKGEQIPDSAKLFLLSRRLNIPMKDLIVSSDDQREPMSSFMFRADNPKENFRLIDQNQVNRIMDDYYELLASFGEASVAYLPPTYKLKLVDHELTEEHKTIIRQAAEQTRKMFGLDHVIPSDIYAVLEHHGIHVIALKTIDKKIDGLSAYSEEKGAFIFLNDHDEIPEERKRFSVIHELGHLIFHREEYRSDLSSLTYSSARREINEKVATLFASYFLIPREQLREYAYYFKRYVTIETIMELKRQFFVSAEAFMRALLDEQYISGRTYGFLRKTLREQGYKEQEPAPIDYIPKNRKLTYFVKQAYFEGSITINKVCEILGCDLRTAREMIKGWYKEHGCSENTGAL
>NC_014915.1|WP_015731688.1|1327955_1329122_+|SEC-C-domain-containing-protein
MSFIQTIEPHLFSDHPVLRQFAFDAIEEYPDIPAALVERLVDEAVTADNEETRRMILHGISKQPLTDRALEQLLTIKDATKYIRWFFPFPAAQLEKYGEQLLPHFPRSWQRAVRLALEGTEDDVWEHYFSVLSHLHEEEFHNHDWFLVAKQAVRILVERGWMTKEDIGLTWMKNEQQPWFSYDGILAVYAISLIGAAEYIPRLARLLEQQDGDVLVDQAVSTLSMFQREETIEAVRPYAFQEDTALSAIHVLANIKSKQAVRVLREVFSKQRDNDLQAFCFEALCHQLDKEAFPEVEQYVKRAEKRGRSWMIDVEQNAYAYYTILEIDHPKLETWKAIAEQRYRHFQAVLQTPPRPTNIPYRRKERKIGRNDPCPCGSGKKYKKCCGK
>NC_014915.1|WP_011230871.1|1327324_1327678_-|hypothetical-protein
MEEKTILAQILQVLDLYAADMRKQFEALHEKFDSLQRQVQALNEKTDEMDKRIEEMDGRFERQIAQLERTVNERFERLEAKLGHIRVELVETQETVDFHSVKIAQHDRKIRHLLHAR
>NC_014915.1|WP_013145643.1|1326365_1327271_+|pseudouridine-5'-phosphate-glycosidase
MNDFLVFSEEVAQAKAEKKPIVALESTIISHGMPYPENVQTAKAVEQIIRDRGAVPATIAILNGKIKIGLTEDELEQLGTSRDVEKVSRRDLPYVVAMKKHGATTVAGTMICAEMAGIRVFATGGIGGVHRGAEQTMDISADLQELARTNVAVVCAGAKSILDLGLTLEYLETHGVPVIGYQTDVLPAFYSRTSPFRVDYRLDSVEEIAQFLETKWKLGLNGGVVIANPVPKEDELEESYITVIIEQALKEAEKQHITGKSVTPFLLDRVKTLTGGKSLQANIALVKNNAALAADLARELS
>NC_014915.1|WP_013523482.1|1325424_1326366_+|ribokinase
MRQAASIVCIGGANVDRKARLLTPFRLGTSHPVTTTQTAGGVARNIAENLGRLAQPVSLVSTVGDDRDGQWLVDVTSRYVNTSFIVRTPKANTGTYTAVLDERGEMVLALADMAIYDTVGEEWLKQQWTRLGPISAVVLDTNFPKAVIRSVIAQCRQEDIPLCVVTVSVPKVKRLPSDLSGVTWFVTNEAEAKEFVGRDGHTDDIMKPILQAGAQNVVVTRGANGVAYATKQGETEAIAAPKVEVTDATGAGDAFAAGFLYGVLGGHTVEDACRFGMSSAALTLQTAETVHPALNEHLLQAAYARYFREGGTK
>NC_014915.1|WP_013523481.1|1324019_1325243_+|YeeE/YedE-family-protein
MELTAQQRDVRAKQAANAPKHLTAWIIAVSCLILIGGTLFLYSLVSWQQALLYVLGAFGGFVLYQAHFGFTSAWRKFILYRQGEGIRAQMIMMAVASALFLPLLVKGSALGHPVSGYVFGVGVSVIVGAFLFGIGMQLGDGCASGTLYHIGGGDANGIVTLIGFIAGSVIATTHFDVWAKMPQLKPFSFIGEFGALGGFLLQLVLLAAVYYVVTVAEKRRYGQLVATSLENRHGWKAIYKGPWSLLVGALLLAVTNALVLMISGKPWGITSAFALWGAKFVQLFGVDPTAWAYWQDEAKRQALANPLYYDTTTVMDISLMVGALLAAALAGRYAKLIQWKRPTRMTIGALIGGLMMGYGARLAFGCNIGAYFGGIASFSAHGWAWFVFAFLGSLIGVKLRPYCAYKN
>NC_014915.1|WP_013145635.1|1338947_1339241_+|helix-turn-helix-transcriptional-regulator
MSDFFKKYAAIRGEQHVQKIQLEGTIAAQIKTRRKQLNMSQQELADRIGVPKSTIGRIEAGLTSPRVETLFKISQALNTPFIIDGTSRQDHNLNVQV
>NC_014915.1|WP_013523489.1|1339684_1342930_+|DEAD/DEAH-box-helicase-family-protein
MKTKGMIDNRQNGLVGDALKAHITKGSKLSIAAAHFTLYAFAELKKELAQIDEFRFIFTEPAFVRGDRSFNEWMKKNEATLYGVEEERKYKIELNQAYIARELAKWLKQKARVKSVVNQRIQGSIYHVRNEDGSQIGLIGGAPFSSPGLGYSSSPHFYFAHIMDDRDSSAQLLRQFEAIWQDEQALQDVKDEILRRLEVMYQEHPPEFIYFVTLYYLFKDFLKEATNYETLQTRTGFQNTVIWNKLYDFQRDGVLGAINKIETYGGCIIADSVGLGKTFEALAVIKYYELRNHRVLVLAPKKLRENWAIYRLNDKRNILAADRFSYDLLNHTDLSRERGYSGDINLEHVNWGNYDLVVIDESHNFRNNDPRNDRVTRYSRLMNDIMKAGVKTKVLMLSATPVNNKLDDLKNQIAFITEGNDKALAETANIKSISQTIRRAQSQFNKWSQLPEEERTTERLLDMLDWDYFALLDSLTIARSRRHIEKYYNVDAIGPFPTRLKPINLKEKIDSKDEFPPLEKINNDILRLRMAVYSPMQYILPNKKADYSEKYDTKVANGRVFKQTDREHNLVYLMKSNLLKRLESSVHSFSLTLQNIIQQIDEHVEKINRCDGSSGTIGEMDGIDAEDPELEEALIGSKVKIFLKDMDLIRWKQDLLYDREILLRLLHQARNVTPDRDQKLLALKRLIEHKIKHPINDQNKKLLIFTAFADTAKYLYENLHQWVQNQFGLHCAVVTGADRPKTTLKMKKVDFNHVLMNFSPVSKERGKVMPEMKDEIDILIATDCISEGQNLQDCDYLVNYDIHWNPVRIIQRFGRIDRIGSKNKQIQLVNFWPSIELDEYIQLVNRVKGRMTILDISSTGEENVIADNSNEMNDLEYRRKQLEKLQNEVIDLEDISGNISLTDFTLDDFRMDLLNFMKEHKEELERAPLGLFSIVANQNEKLKDEIQPGVIFCLKQTAPMASAHEQNALYPYYLVYVREDGTVLYNHVHVKKVLDLYRSLCNGKKDVEWGLYKAFYQETKNGKDMGQYKALLEKAVEEIVGKMDQQLMLNIFSLGNLDAFVTNANTSLQDFEIVSYLIIKG
>NC_014915.1|WP_013523490.1|1342935_1343760_+|DUF4391-domain-containing-protein
MAASAFYATIGLDERVRPLHKKLDKKMFYDYADLTKKEKDYMTKDIERIELTYLLTSGIINIQPFVNDDYHYEGVMFITVRLRPESKDAHVSVIGEIIQKTVPNPTVIVFEKEGNVRIGTCRKRLNKNDRTKVVAEEWAYTPWFSLDHADETVKQFLRAVHMTKLSFANFFRFYQDIHLAVQAFQHAKAIGAFYIAADEQSKQLVAQIEQAEVEIAKWKNEIKKETQFNRKVEYHLKIQQLTKQIEQWKQQLRGKEQHDGETGWKIARPCQNKH
>NC_014915.1|WP_013523491.1|1343710_1345657_+|site-specific-DNA-methyltransferase
MEKLDGKSLDLVKTNIEALKQLFPEVVTEGKIDFDKLKLVLGEEIETRNEKYEFTWHGKTQAMKLAQTPSTGTLRPDKASSKNWETTENLYIEGDNLEVLKLLQKSYFGKIKMIYIDPPYNTGKDFVYKDDFHDNIKNYKEITQQMAKANTETNGRFHTDWLNMMYPRLKLARNLLREDGVILVSIDDVEYANLKKILDEVFGQENFVGSFIWSAGRKNDSKYISISHEYILCYFKNMEFVREREIVWREKKEGLKEIYDTAQKLLKECNEDYKLASRLLKEWYNSLPDNHPSKQHKHYNCVDERGVYFPSDLSKPEANGARYEILHPVTNKPVKQPAGGWRYMNKEKMLELINNNRIHFGEDETTIPCYKRYLFESEYQVPYSVFYQDNRSASKRLKDLFGKKVFDFPKDENIIKKLISIASYAQEGANSSTNDIILDFFSGSATTAHAVMQLNAEDGGNRKFIMVQLPEKTDETSDAYKAGYKNICEIGKERIRRAGEKIVQETGKTDLDIGFKVFKLDSSNIKEWDPDFDNLEQTLFDLQNNIKEDRTKEDLLYEILLKIGLPLTVPIEEIDCRGKTIYNVAYGSVLVCLEDEIDLDLVQEMLNYRSEHLPPKVIFKESGFMSDAVKTNALQTLKKHGITDVRSV
>NC_014915.1|WP_013523492.1|1345660_1348615_+|DEAD/DEAH-box-helicase-family-protein
MKLKFNADLDYQRRAVESVVHIFKGQELSQSNFTVSYGPDAGMLQTDLGVGNRLDLTPEEILKNVQDIQVRNGLPRSERLDGMHFTIEMETGTGKTYVYLRTIYELHKHYGFTKFVIVVPSVAIREGVYKSLQITRDHFDELYDRTPAEYFIYDSQKLDQVRNFATATTIQIMIINIDAFRKSFEDPEKEDKANVIHRPNDRLNGYRPIEFIRQTNPIVIIDEPQSVDTTPKSKEAIASLNPLCTLRYSATHVDKYHMVYRLDAVDAYNQKLVKKIEVMSVRSEPSFNVPYIKLVEVKERKAKLELDVESRGKIKRTTKTVKYGDDLYDVSGERELYRGYIVEQIDWTEGNEAVEINGYRLRVGDAIGDVDDDAIKRYQIRKTIEEHLNKELWLRPRGIKVLSLFFIDKVAHYRDYDQNGNPIKGKYASMFEEEYRNLMQKPKYRPLWDDPGIDQDIEKVHNGYFAQDKKGRLKDTKGNTEADTDVYNLIMRDKERLLSLDEPLRFIFSHSALREGWDNPNVFQICTLKDSSGTYVSRRQEIGRGLRLAVDQNGERVHDDHINILTVMANESYEEFVATLQKEIEEDTGIQFGKIEKHVFAKLVYVDEATDEPVQMGYDLSLKLYEELKQNGYIDKQGKATEKLKRAIENYDLHLSDEFQPWRSSIVKEIKRHLQALPIKDGTKKKKVHVNMAVLNQEEFRRLWDKIKYKTVYSVDFDSEQLIDLCIAAIQEMRPIEKIRIVSRKGRVEIDHVTGVQAQTISEKVEDYVSLHHTLPDVVTELQNRTNLTRKTIVRILTGCKRLDDFKNNPQKFIEEVANIIQRQMRLLLKDGVKYYKIGDDAYYAVELFQNEELLAYLNDNAIPSEKSPFDHILYDSDVEERFAKRFEHDENVKVYVKLPSWFKIDTPIGSYNPDWALVIEKDGEEKLYFVLETKGQEWEDELRPGEAAKIAFARKHFQALGTDVEFIGPENDVERFMLRALSR
>NC_014915.1|WP_013523493.1|1348969_1349488_+|hypothetical-protein
MATIRKADYYYGALLSALVNGGLAPALFEKENDNRQIYEVTTNKASYIMYTKYNTNPSGSKDFTWSFVFSDHEIAEINKIYLEHSKEKEIMFAFVCAQKQPSDSNQVITIVRWNEFLECVDLQRQQVRGTPRLSIKAVKGSPKLRLYGSKRADVLDGKDHTIKIERNRLNSL
>NC_014915.1|WP_012820563.1|1349758_1351039_+|IS110-family-transposase
MNCTQNYKIDQVTEQTLVVGIDIAKRTHYACFVDDRGRVLRKSFPIFQSKEGFRQLYEAIQEAMQAFGKPQVIVAVEPTGHYWLNLAYFLEEHGIPLVMVNPAHVCRSKELDDNLPTKHDAKDALVIARLAKDGRFLVPRLLHEIEADLRVGSTLKEKLRKEQTAVKNAIVRWTDRYFPEFWTVFRDLGKTALSVLEWTPLPADMASRSAEELIEVYRQSEGLKCPQKAKIQALIDAAKDSIGVTEGTTMARFEIAALVRRYRQLEAEIAALDAELKALVQTTMEYQWLKTVDGLGDATIIDLLAEIGSFAHYRDPRQLVKLAGLTLKENSSGQRKGQKHISKRGRKRLRSVLFRAMIPLIRHNEAFRELHDYYTTRPVNPLTGKQSIVALCRKLLNVLFAICTKKQAFDAERMKQDVLSQVQRAA
>NC_014915.1|WP_013523494.1|1351434_1352424_+|restriction-endonuclease
MSKWWMIRAGDRNELIPLWLEKGIASIGWARLGDPKNFQSKEQLQRKADEVFAESKPKSRTSWVNQVWRFAHEIKKGDRVITYSKEKREYIVGTVTEEHRYDPAIGHPYYPNIIRVKWENATVPRDSLSDGAKNSLGSTLTVFRVDEWGDEIEQRLNSQSFPKPRDESEEGETEEIVEDLVGKALMMIQDKVDKLDPWQMQDLVAGLLQAMGYNVQVSPKGPDGGVDVLAYKDAFGFEKPIIKVQVKHRKSAASAPEIQQLLGANPIDANCLFVSTGGFTSHAEAVAKHNSVKLIDLEELVNLIVHWYENMPSDARALLPLQKMYVPES
>NC_014915.1|WP_013523495.1|1352494_1353799_-|acetamidase/formamidase-family-protein
MEAKQTVFVNEFTNGILDPHGNMLGPVQDGGYIVANTTPGCWGPMITPCIRGGHEVTKPVFVEGAEVGDAIAIKIKSIRVTSIATSSGNDKPMEGRFVGDPFVAVKCPQCGTMYPETKIEGIGPEAIRCANCGADVTPFVFTNGYTMTFDPNRQIGVTVHKEAAEHIARQGRYYMATPDNSVQNPIVTFAPHDLVGTVARLRPFLGQLGTTPARPLPDSHNAGDFGQFLINAPHEYGITKEQLEDRTDGHMDINRVREGAVLICPVKVRGGGVYLGDMHAMQGDGEIAGHTTDVSGIVTLQVKVIKGLTIDGPILLPVAEDLPYLAKPLTKKEKEIALDLAQSWGVDKLEESLPISFVGTGANLNEATENGLQRAAKTLGISVPEVMNRATITGAIEIGRHPGVITVTFLCPIRYLDKISLTSLVYDQYRSVLE
>NC_014915.1|WP_013523496.1|1354018_1354228_+|hypothetical-protein
MNSSIEKKLREKGIKCSEQELMMLEHQWKAIQQLKQGVEKLGLNEEDIGVVHQPGGVYRGKTAKYENNL

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Crispr_ID: NC_014915_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014915_5

1981010-1981107

Orphan

Consensus_repeat	Method
GTTTCAGTTCCTCATGGGCACGATAAAAAACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014915_5

>merge|NC_014915|5|1981010-1981107|CRISPRCasFinder
GTTTCAGTTCCTCATGGGCACGATAAAAAACCTGGCCCGGCTTGTCGGAGATGACCGTTGTAAACGGTTTCAGTTCCTCATGGGCACGATAAAAAACC

>NC_014915|5|5|1981010-1981107|CRISPRCasFinder
GTTTCAGTTCCTCATGGGCACGATAAAAAACC	TGGCCCGGCTTGTCGGAGATGACCGTTGTAAACG
GTTTCAGTTCCTCATGGGCACGATAAAAAACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014915.1\|WP_013523955.1\|1977825_1978842_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_014915.1\|WP_013523954.1\|1976236_1977808_-\|gluconokinase	unknown	unknown	gnl\|CDD\|130381
NC_014915.1\|WP_013523950.1\|1971681_1972938_-\|urea-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|132448
NC_014915.1\|WP_013523964.1\|1991776_1992937_-\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NC_014915.1\|WP_013145121.1\|1986210_1986666_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	unknown	unknown	gnl\|CDD\|377815
NC_014915.1\|WP_013523962.1\|1986721_1987762_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270234
NC_014915.1\|WP_013523956.1\|1979083_1979605_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271206
NC_014915.1\|WP_041468368.1\|1970725_1971625_-\|urea-ABC-transporter-permease-subunit-UrtB	unknown	unknown	gnl\|CDD\|200272
NC_014915.1\|WP_013523963.1\|1988124_1989030_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NC_014915.1\|WP_013523961.1\|1984670_1986197_-\|tripartite-tricarboxylate-transporter-permease	unknown	unknown	gnl\|CDD\|225870
NC_014915.1\|WP_013523966.1\|1993385_1995476_-\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NC_014915.1\|WP_013523965.1\|1992936_1993380_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NC_014915.1\|WP_013523960.1\|1982987_1984598_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827
NC_014915.1\|WP_013523959.1\|1982281_1982974_-\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NC_014915.1\|WP_013523958.1\|1981286_1982222_-\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NC_014915.1\|WP_013523957.1\|1979910_1980837_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NC_014915.1\|WP_013523952.1\|1973256_1974654_-\|chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NC_014915.1\|WP_013523948.1\|1968918_1969683_-\|urea-ABC-transporter-ATP-binding-protein-UrtD	unknown	unknown	gnl\|CDD\|274568
NC_014915.1\|WP_013523949.1\|1969657_1970716_-\|urea-ABC-transporter-permease-subunit-UrtC	unknown	unknown	gnl\|CDD\|132449
NC_014915.1\|WP_041469466.1\|1974772_1976122_-\|GntP-family-permease	unknown	unknown	gnl\|CDD\|308194

Protein	Function_ID	Function_description	E-value
NC_014915.1\|WP_013523955.1\|1977825_1978842_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.06822e-109
NC_014915.1\|WP_013523954.1\|1976236_1977808_-\|gluconokinase	gnl\|CDD\|130381	TIGR01314, gntK_FGGY, gluconate kinase, FGGY type. Gluconate is derived from glucose in two steps. This model describes one form of gluconate kinase, belonging to the FGGY family of carbohydrate kinases. Gluconate kinase phosphoryates gluconate for entry into the Entner-Douderoff pathway. [Energy metabolism, Sugars].	0
NC_014915.1\|WP_013523950.1\|1971681_1972938_-\|urea-ABC-transporter-substrate-binding-protein	gnl\|CDD\|132448	TIGR03407, urea_ABC_UrtA, urea ABC transporter, urea binding protein. Members of this protein family are ABC transporter substrate-binding proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. Members of this protein family tend to have the twin-arginine signal for Sec-independent transport across the plasma membrane. [Transport and binding proteins, Amino acids, peptides and amines].	0
NC_014915.1\|WP_013523964.1\|1991776_1992937_-\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NC_014915.1\|WP_013145121.1\|1986210_1986666_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	gnl\|CDD\|377815	pfam07331, TctB, Tripartite tricarboxylate transporter TctB family. This family consists of several hypothetical bacterial proteins of around 150 residues in length. This family was formerly known as DUF1468.	5.72181e-11
NC_014915.1\|WP_013523962.1\|1986721_1987762_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl\|CDD\|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	7.81393e-96
NC_014915.1\|WP_013523956.1\|1979083_1979605_+\|hypothetical-protein	gnl\|CDD\|271206	cd14247, Lmo2686_like, Uncharacterized hexameric protein conserved in Bacilli. This family conserved in bacilli contains proteins that form an unusual hexameric arrangement via circular domain-swapping of a beta-hairpin-beta unit.	1.99976e-65
NC_014915.1\|WP_041468368.1\|1970725_1971625_-\|urea-ABC-transporter-permease-subunit-UrtB	gnl\|CDD\|200272	TIGR03409, urea_trans_UrtB, urea ABC transporter, permease protein UrtB. Members of this protein family are ABC transporter permease proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	4.70818e-148
NC_014915.1\|WP_013523963.1\|1988124_1989030_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	1.31684e-12
NC_014915.1\|WP_013523961.1\|1984670_1986197_-\|tripartite-tricarboxylate-transporter-permease	gnl\|CDD\|225870	COG3333, COG3333, Uncharacterized protein conserved in bacteria [Function unknown].	0
NC_014915.1\|WP_013523966.1\|1993385_1995476_-\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	6.90885e-66
NC_014915.1\|WP_013523965.1\|1992936_1993380_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	6.08516e-59
NC_014915.1\|WP_013523960.1\|1982987_1984598_-\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	0
NC_014915.1\|WP_013523959.1\|1982281_1982974_-\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.28036e-88
NC_014915.1\|WP_013523958.1\|1981286_1982222_-\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	8.06261e-32
NC_014915.1\|WP_013523957.1\|1979910_1980837_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	1.23038e-15
NC_014915.1\|WP_013523952.1\|1973256_1974654_-\|chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	1.69292e-31
NC_014915.1\|WP_013523948.1\|1968918_1969683_-\|urea-ABC-transporter-ATP-binding-protein-UrtD	gnl\|CDD\|274568	TIGR03411, urea_trans_UrtD, urea ABC transporter, ATP-binding protein UrtD. Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	1.68013e-152
NC_014915.1\|WP_013523949.1\|1969657_1970716_-\|urea-ABC-transporter-permease-subunit-UrtC	gnl\|CDD\|132449	TIGR03408, urea_trans_UrtC, urea ABC transporter, permease protein UrtC. Members of this protein family are ABC transporter permease proteins associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines].	1.56313e-161
NC_014915.1\|WP_041469466.1\|1974772_1976122_-\|GntP-family-permease	gnl\|CDD\|308194	pfam02447, GntP_permease, GntP family permease. This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter, and GntT, a high affinity transporter.	8.02114e-173

>NC_014915.1|WP_013523957.1|1979910_1980837_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MARKRIDHDRLFKELLSTFFEEFLLLFFPHVYEHIDVHHLSFLSEELFTDVTAGEKHRVDLLVETKVKGEDGLVIVHVEHQSYTQRTFPERMFLYFSRLFQKYRRRILPIAIFSYDEQYDEPSSLVMQFPFLTVLDFRFLTVELRKQPWRQYIHQDNPVAAALLSKMGYNEEEKVEVKKEFLRMLVRLELDEAKQRLLFGFFETYLRLSEEEEAKLRNEVSQMETKEAKRVMELIVSYEQRGMEKGIQTGIEMGIKQGMKQGMKQGRQQGIEEGKLDVVKRMLAKGYDVDTIHELTGLPVETIEKVKQ
>NC_014915.1|WP_013523956.1|1979083_1979605_+|hypothetical-protein
MVTFTIQEHSHFLYPLFFLCIPILKSQVQLVVKSQKIYNENGEYVGTLGIEPVLSAGSNDNIMSALASYKVGTGNSTWKIYWYSGTVNYHFYVDINIGSTGLATITRAYNGWYFITPPYTVKKDWISILRKTETYTLPAEARYHLTLNSIWGGEWTIYLYARVKDQTLYTGTN
>NC_014915.1|WP_013523955.1|1977825_1978842_-|LacI-family-DNA-binding-transcriptional-regulator
MKKVTMADVAKLANVSKSTVSQYLNKRYEYMSEETRKRIAEAIEELGYQPNVIARSLKQKTTATIGVIVFNMLHMMTTQVLHAIEEECQKRGFQVIVCNSGDDPDKEKTYIETLLAKQVDGMIVFPTGKNEEVYRRLVEERFPLVFVDRMVPGVGADSVLLDNAGAAEMAVQYFASYGYERIAIVTPPLVPYNVPRMERFEGFRAAMEKRGFEVGDQNVIAAEPAALPEVLKQRLAEPKRPNALFAINDLTLMGVLRFVKETGIRMPDELAIINIDDVPFADIYTPALTTIAQPTFAMGKKAAERVFDQMKAKKTDGPRVFRFSPVLMERTSIRRGKA
>NC_014915.1|WP_013523954.1|1976236_1977808_-|gluconokinase
MAIHGDVVIGIDIGTTSTKAVVFDGRGKVLASHAVDYPIIQPHPGFAEQDPDELFAAVIQAVGAVTVRYGIRPEQVKAMGLSAAMHSIMALDESGRPLTRLLIWADNRSVAQAERLLKEQNGLAIYRRTGTPIHPMSPLSKLLWLKEEQPDVFQQAHWFVSVKDYVLYRLYGDYVADHSMASATGLFRLDTLDWDEEVLALVGLRREQLPRLVPATHVLSGMKKEWAEKMGVPPDVPVVIGASDGVLANVGVGAVLPGEAAITIGTSGAVRTIAATPTTDEKGRTFCYALTPGYWVVGGPTNNGGILLRWLRDEFGAQEREVAKKLGMDPYDLLTKYAERVPPGSEGLVFLPFLSGERAPYWNANARGTFFGLGLHHKREHFIRAVMEGVCFSILSVALAIRDVTGPMTEIRVSGGFAKSPFWRQMLSDMLGKPLIVPQTHEASALGAAAVALYALGELPSLETVKTWIDTTARHEPKEEHTLIYAELFDLYARLYERLKEEFNIIAAFQRRNGAKGSETKSV
>NC_014915.1|WP_041469466.1|1974772_1976122_-|GntP-family-permease
MGIAIVVAAIIVLLLLITAAKMHPFVALILVSVGVGLAMGMPLIAPSPETPGIIDSIKAGLGNTLGFLAIVLALGTMLGKMMAESGGAERIAKTLIDRFGQKRVHWAMMVVAFLVGIPVFFQVGFVLLIPLVFTIAMETGISLVTIGIPLVAGLSVVHGLVPPHPAAMAAVGIFKADVGKTILYSIIVGLPTAIIAGPLYGKWIGSRMYKKVPAEIAEQLVQHKEARELPGFGNTLFTILLPVILMLIASIANVTLDQKSEAAKVLRFIGDPIVAMLIATVYSFFSLGYARGFNRDTVLKFANDCLGPVANILLIIGAGGAFNKVLLDSGIGEQIAEVAKHSHLSPLLLGWGIAALIRVATGSATVSMMTAAGIVAPIAATMPGTNVELLVLATGAGSLILSHVNDSGFWMIKEYFGMTVKETLMTWTAMETIISVVAFVFILLLNMVL
>NC_014915.1|WP_013523952.1|1973256_1974654_-|chemotaxis-protein
MIFARRAERKTRRESDWPRQEGKREERKQIARQIVVAVDQLKAVMEQMKLAAVLLNDISDSSRNSAAELMDHSEKTVEYTEKVAKKMRAIEEAAKEIAASSNDIHASSRQFSEQWLHSWNSLETLQKEIRTLRSQHETLLKQMNHLVHHSQRINQIISAIGEISQKTKILSLNANIEAARAGEHGRGFAVVAREIGMLASQTSEAVQQTQDILSLIQREIAATTDIVREETKQIDVEEKEMEAIMAFLHSLQRQLNDMTDLVSSSVQSASGQSDSVKEIAGLLEEIVQLSRENQRFVERVTADMNEQHESVGQILRINEALQKTAEELQQTVGRDWMRETISVDDAVVKNMIQKLSALLQSAPLEQMDEAMHRRVLDRFLSENGEIEAVWSNRLDGTFVYSNPPAGLVNAKVRSWFQEASGGTVYVSDPYVSALTKHLCVTVSAPITDHNGQIVGVIGADLALSK
>NC_014915.1|WP_013523950.1|1971681_1972938_-|urea-ABC-transporter-substrate-binding-protein
MKPTFMRKLWLLLCISVFALGGCAASSAVDQAKNENKKDSSSASKEGGTVKVGILHSLSGTMAISEVSLRDAELMAIEEINASGGLLGKKIEPVVEDGASDWPTFAEKAKKLLQKDQVAAIFGGWTSASRKAMLPVVEQNNGLLWYPVQYEGMESSPNIFYTGATTNQQIVPAVSWLLKNRGKTFFLLGSDYVFPRTANKIIKAQLKAEGGQVVGEEYTPLGHTDYSTIISKIKQVKPAVVFNTLNGDSNVAFFKQLKDAGITPKDVTVMSVSIAEEEIRGIGPDVLAGHLAVWNYFQTTDTPENKAFVQKYKEKYGQDRVTDDPIEAAYTAVHLWAEAVKKAGSFDVDQVKKAAAGLEYKAPEGTVKIDGETQHLWKTVRIGEIQADGQFKELWNSGQPVKPDPYLKSYPWAKGLSE
>NC_014915.1|WP_041468368.1|1970725_1971625_-|urea-ABC-transporter-permease-subunit-UrtB
MAMFIDQLFNGLSVGSILLLIAIGLAITFGLMGVINMAHGELMMVGAYTTYVIQRWFTSHMPHSAGLYFVAAIPLSFLAAALLGWGLEKSLIRHLYRRPLDSLLATWGISLILQQTARLIFGAPNVAVVPPSWLDGGIRLFGAVFPYKRLFLLCLVLAIVFFLYMYLMKTRAGRRIQAVTMNRSMAACLGIATQKVDAYSFAIGSGLAGVAGCALTLLGPIGPTIGTYYIVDAFMVVILGGVGKLAGTLLGAFGIGLISTFVEYSTSATIAKVIVFVLIIAFLQWKPSGLLSVRTRSLD
>NC_014915.1|WP_013523949.1|1969657_1970716_-|urea-ABC-transporter-permease-subunit-UrtC
MVNKRWGYWLFFAALFLAPFYLTEFRLSLLGKFLCFAIVAVGISLIWGYTGILSLGHGVYFGLGAYCMAMYLKLEASQGHLPDFMEWSGVRELPWFWKPFAHPMVAIAAAIALPTLLAALLSYLTFKNRIKGVYFSLLSQAVVVVFVTLFIGKQEWTGGTNGLTNFSTVFGFSLSSPLTQIVLYWLTTACLALIFVAARRLTSGRLGKVLIAIRDAENRVRFLGFNPTVYKVFVYSLSAAFAGVAGALFVLQVGLISPEMMGIIPSIEMVLWAAVGGRQSLMGAIIGAVVMNTAKSFLSENYPDLWLLLLGALFVVVVLLVPKGLAGIYESLVAVLIKAKRGHEREARVDVS
>NC_014915.1|WP_013523948.1|1968918_1969683_-|urea-ABC-transporter-ATP-binding-protein-UrtD
MKPVLMCRDVVVDFDGFRALQGVDLAVYPHEVRFLIGPNGAGKTTLLDVICGRTRATDGRVLFFSHDITKRPEYEIVQMGIARKFQSPSIFPFLTVWENMELAMRQDQRLRSVLRAKRTGEEEEIMAAQLERIGLLDERHRLAGTLSHGQKQWLEIGMQLIQRPQLLLLDEPIAGMSAAERERTGEWLHEIAKHCAVIIVEHDMDFVRRYSKQVTVMHEGKVLCEGSIDEVQQNEQVIDVYLGRRKNACYASGM
>NC_014915.1|WP_013523958.1|1981286_1982222_-|AEC-family-transporter
MAVFSGILLQVMVPMLLIVGLGAGLHRFFHLDLNTLSKLNMYVLLPAVAFINVYDSELNGKVLAAILGFLLLQNSGLIVLSMMMAKLFKLERSLSAVFQNTIVLNNSGNFGIPVSQLVFHQHPLGATIQIMVTIFQNFLTNTYGVYQFVSGNGKKEKWTAEIWKNPVLHALFLGLVCRWLHVPIPSFLWTPLQRVADAFLAIALFTLGAQIAYARFTALPPLVYVSVFGRLILSPLLAASLIFLLGIDGVTAQALLIASSYPCSRNTALYALEYDCHPDYAAQAVLVSTLLSAITVTGVVYAARLLFPIGG
>NC_014915.1|WP_013523959.1|1982281_1982974_-|response-regulator
MLPIRVLIIEDDRRIAEINRRFVEKVNGYEVVGIATNAEEARELTEVLRPDVLLLDVYFPDMNGLSFLKWVREHFSDIDIIMITAAREVDVLKQALHGGVFDYIIKPIMFDRFVETLNRYKEYYDKMQRWVKEKEWIGQEDVDALIGREVSVKDQPMLPKSIQPLTLEKVLAVVRQCPEGITAEEVGRQIGTSRTTARRYLEYLVSIDQVTADITYGSVGRPERVYKKKM
>NC_014915.1|WP_013523960.1|1982987_1984598_-|sensor-histidine-kinase
MKLQTRLMVIICSLLLLVIVVLTFLFQHMFATTLKQQIGMRALNVAETVASTPLVREAFRDPNPSVRLQPFAEHIRRKTGAEYVVIGNHEGIRYAHPLPDRIGKHMVGGDNGEVLKGKAIISEAVGSLGPAIRGKAPIFDENGHVIGIVSVGFLLEDIQRTVWSYRMKMFLFSVFALFLGAVGAMAIASTVKKSIHGLEPEEIGLLYQEKQAILEAIREGIVAINQEGTITMVNQTALKLLGYENERDVLGMPILQLIPHSRLPEVIRTGQAEFDDEMVLGEETVIANRIPIKDKTGGVIGAVSTFRNKSELYRLTKELSQLRSYADALRAQTHEFSNKLYLISGLIQLESYEEALELIAKETDLQQNIVRFVMKEIPDPIIGGLLIGKFNRANELKIVFEIDRESSFRDVPPWMDRDHLVTIIGNVVDNAMEAVLHNGKEEKRVAIFLTDLGDDLIIEVEDNGLGIDPVVAERIYDRGFSTKAARGRGYGLDLVNRALTMLGGQMTYRSEQGAGTVFTIMIPKRPAHVGRQCRQG
>NC_014915.1|WP_013523961.1|1984670_1986197_-|tripartite-tricarboxylate-transporter-permease
MSTLSFLLDGFQTALQPHNLLFAFIGVLIGTAVGVLPGIGPMSGVALLIPVTASMTSGLSPEQAAASSIILLAGVYYGAMYGGSTTSILLNTPGESSSVVTTLDGYQMARQGRAGAALAIAAIGSFVAGIVALIGLVLLAEPLSNVALKFGPAEYFSLMLLGLAAVSGLAGKSMTKAWIMTVFGLLLSTIGLDNVSGVARFTYNISYLYGGLEFLTVAVGLFALGEVFKSILHNEMNSGEIAKIGRVLPTKADLRESAGPIARGSLLGFFIGVLPGAGATLASFFSYILEKKISKHPEKFGQGTIAGVAAPESANNGASGGAMIPLLTLGIPGSGTTAILMGALIMYNVQPGPLLFDEHPAVAWGLIASMFIGNVMLLILNMPLVKIFAKIIQTPTKYLLPLIIAISVFGVYAVQVTTFDVFLLLAFGLLGYWLAEHDYPLAPLVLGLVLGPMIENNMRRALTASNGDYLVFFEKPISLVLLVIAFLWIAVPFVVKLRGKSVVINEDM
>NC_014915.1|WP_013145121.1|1986210_1986666_-|tripartite-tricarboxylate-transporter-TctB-family-protein
MNKTADRIAAAAFLAVGALFMAESLRLSKSAYGSAVGPNVFPFLLGLVLVFLSIKLLFETRSYSDAAGEKPPRQYKKFLIIFIAAVFYAALLETVGYVITTFLFLVIGFQTMEKGALWKSIAIAAGFSLGVYGLYVKLLQGTLPSWPIWFQ
>NC_014915.1|WP_013523962.1|1986721_1987762_-|tripartite-tricarboxylate-transporter-substrate-binding-protein
MKKKRWWGLLAAGMMTLALAACSGNDASGSKSSGSNSGSSASNYPTKPITIVAPSGAGGGWDLTARAITKVLDETGLVKQTMTVENKPGGGGAVFMAEYATQDVKNDYKLFVNSPPIIINNLKKEGNSPFGYKDTTPLAQLTKDFGAIVVKADSKFQSLTQLLDAIKQDPKSVTVAGGSAPGSMDHLVAILPIYKSGIDPKSVKYVSYDGGGEAMAALLGGNADVIATDASSVGEYLKAGKVRVLAVSAPERLGGVLKDVPTMKELGLDAEFTIWRGVFGPKEMSSEAKAFWEETLKKLSEHEKWKEELQKQGWEAEYRNSEEFTKFLKEQEQQIGDLLKSLGMHK
>NC_014915.1|WP_013523963.1|1988124_1989030_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAIDHDRLFKELIQTFFEEFLLLFFPDMHEHIDFSHLSFLSEELFTDVTAGEKYRVDLLVETKLKGEDGLIIVHVENQSYVQPSFPERMFIYFSRLFEKYRTRIVPIAVFSHDTLREEPSVFSIEFPFGDVLQFRFFPVELRKKHWRDYIRHDNPIAAALLGKMGYTESEKIVLKKEFLRMLVRLELDEARQRLLLGFFETYVKLSEEEEQQLQREVKEMETTEKEKMLELIISYEQRGRKQGLEEGVKRGIEQGIKQGMKQGMKQLIRNMARKGMKVEDIARLVDLPEQDVRELLEEQGN
>NC_014915.1|WP_013523964.1|1991776_1992937_-|mannitol-1-phosphate-5-dehydrogenase
MRAVHFGAGNIGRGFIGSLLAASGYDVVFVDVNEQIVRLLKERGEYRVIVAGEQQEEQWVRGVSALNSQTEREAVIEAIADADLVTTAVGPPILPAIAPVVAAGLQRRFAIQQKPLHVIACENMIAGTEALKTHVFEHLSADEQRLANQSVGFLNCAVDRIVPNQTNDDPLAVTVEPFFEWAIEARNVIGAVPPIQGAHFVADLGPYIERKLFTVNTGHALAAYLGYLRNYETVQEAMNDEDIRWNVEQALSESGAVLVKKHGWDANEHRAYIDTTIGRFMNPSLSDDIIRVARSPIRKLGPNDRLVAPATQYYALFERVPFGLVKGIAALLRFDDASDAEAAALQQTLKQRGVEEALWQYAGLDRGHPLIAAVKEEYGRMEKNKS
>NC_014915.1|WP_013523965.1|1992936_1993380_-|PTS-sugar-transporter-subunit-IIA
MLAHSILNKENIVLNAQPKTKEEAIRLAGEVLVKQGYVDPAYVDAMLEREELTSTYIGNNVAIPHGTEAAKALVKHSGISIVQVPDGVDFGGGNMATIVIGIAGKDGEHLDILSQLALVCAEADHVEAMANAKTEEEILALLHEVNG
>NC_014915.1|WP_013523966.1|1993385_1995476_-|BglG-family-transcription-antiterminator
MYVSARERKLLERLLADDRDITVGELAEELNVSARTVHRDLQGIESVLRRYGLGLAKKAGIGIRLVGEEENKQALAAELFRLSHHEYTPEERQLMIFIALLEANEPVKLVSLATDLNVTVATVSLDLDKVEQTVEAYGLSLIRKRGYGVELAGSESAKRRLMSDLLFRHVDEHEFLALMKETIQKRADAPLDTVAEKLLGLVDRKKLSIIEQQIERVKEKLPFTMADSSYIAFVVHLALAIERIKQGEAIHFDPRDLQALQATKEYEIARVLAESLERAFGIDIPNEEVGYMTMHLMGAKWRSRQGAMMEEPSLAVGMKAQQLIRFVSDKLGVDLSTDRTLYEDLVVHLKPALYRLEHGMGVANPLLDQIKQDYAELFAIVADGARQLFGDIPVPDEEIGYLVLHFAAALMREKKGWRVLVICSSGLGTAKMLATRLKKEIPDIVSLEQASAFEWRGKDVSAYDLVISTVPLPEEYGPHIVVSPMLTEEEARKIRECLERKSAAEKRMEREPTAQRNRPALDIMKAVRRISETIVHILDGFSLAAVTHRSVRELLADACRRLERNGFIVDADVVIEELRRRESLGGLGVPGTTLALYHARSFAVLRPSLTMYRLDSPQTVAGMDGEPMEINTVVLLLGPADADEEMLSVLSHVSTLLVKDEQSAATLAYGGEDEVYSLISGHLEQFFDHYWTSTKE

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Crispr_ID: NC_014915_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014915_6

1989131-1991594

Orphan

Consensus_repeat	Method
GTTTCAATCCCTCATAGGTACGATAAAAAC	CRISPRCasFinder
GTTTCAATCCCTCATAGGTACGATAAAAAC	CRT
GTTTTTATCGTACCTATGAGGGATTGAAAC	PILER-CR

37 spacers

The CRISPR arrays of NC_014915_6

>merge|NC_014915|6|1989131-1991594|CRISPRCasFinder,CRT,PILER-CR
CGCTTCAGTCCCCACAGGTACGATAAAAACGTATTCCTGCACCACGTGATTGTTTCAATCCCTTATAGTTACGATAAAAACAAAATGATCCGGCTAACATTATTCAAGAAGTGAAAATGTTTCAATCCTCCATAGGTACGATAAAAACGGACAAGCGAGGAGTTGAAAGCATGCGCGACCCGTGTTTCAATCCCTCATAGGTACGATAAAAACCCAATTTTGCCTGGTCGTAGCGGCGGGCGTCAATGTTGGTTTCAATCCCTCATAGGTACGATAAAAACCGTTTCCGGCTGCGCGAGCTGGGGCGAGATGAAGCCGTTTCAATCCCTCATAGGTACGATAAAAACAAGAAATGCAACGGCATGGTATTGATGTCTCTATTGGTTTCAATCCCTCATAGGTACGATAAAAACTAATCTTGAACCAGTCCATAAAATAGTTGTCGATCTGTTTCAATCCCTCATAGGTACGATAAAAACATTTTGCCTGGTCGTAGCGGCGGGCGTCAATGTTGGTTTCAATCCCTCATAGGTACGATAAAAACCAGCGTTGGAGCGGTTTTGTCAATGTTCGACACCGCAGTTTCAATCCCTCATAGGTACGATAAAAACGCGGCAAATCTTCCTTAGCCCTTGCTTCGTCCGGTTGTTTCAATCCCTCATAGGTACGATAAAAACATGAGTGGAACGAGAGCCGCCGCAATAGCAGGGGAGTTTCAATCCCTCATAGGTACGATAAAAACCCGATCAAAATACATGAACAATTGGAAACATTTTATCAGTTTCAATCCCTCATAGGTACGATAAAAACTAGGGAGGATGATTCACTATGACACTTGTCGAAGCTCTGTTTCAATCCCTCATAGGTACGATAAAAACCACTCCCCTTATTGCCCGTCCGATCGTCTCGGGCGGGCGTTTCAATCCCTCATAGGTACGATAAAAACGTAGGGAGGTTAGAAAAAACAAGGATTGAAAATGACGTTTCAATCCCTCATAGGTACGATAAAAACATGCCGGATAGCGCCAACAAGACGTCCCGTGTCAAGTTTCAATCCCTCATAGGTACGATAAAAACGGTTTCGCAACTTGGGCGCCCTCAAACACTACCGAAGTTTCAATCCCTCATAGGTACGATAAAAACTGTAGAGCGCTATTATGCTGGAAATCCGCCACAACGGGTTTCAATCCCTCATAGGTACGATAAAAACAAGGTACAGGTCAGATTTTCCATCACTACAGCATGGTTTCAATCCCTCATAGGTACGATAAAAACGCAAGAGCCATCGCTGACGCTGTTTCTAAAACGATGTTTCAATCCCTCATAGGTACGATAAAAACACGGCTTCTTTCCAGCAAGCACTTTCAGGTTTTTCGTTTCAATCCCTCATAGGTACGATAAAAACAGTGTTTAGTTCTGATAGATGAAGCAGGTATTATGTTGTTTCAATCCCTCATAGGTACGATAAAAACGGAACGTTTTGCGATTTATGACAATGAGGGCTATGGGTAGTTTCAATCCCTCATAGGTACGATAAAAACCCGATCACGCACCAACTCGTAGTCACTTTTCCCAGTTTCAATCCCTCATAGGTACGATAAAAACTTTTTGCTGTGTTTGGTGTATTTGATGAGTTGCTCGTTTCAATCCCTCATAGGTACGATAAAAACGTATAGCGGCACAGCCTCCGGAAAATTAACTAAATGTTTCAATCCCTCATAGGTACGATAAAAACGCAGCTATACCAGGATATGTTCCCACTGAACTCGGCTGGTGTTTCAATCCCTCATAGGTACGATAAAAACTTAACGGCATGCGCTCCCACAGATACGGCTTCTCGTGTTTCAATCCCTCATAGGTACGATAAAAACGAGAGCTAGTGATTTTTACATGTTGCTGTTACAGTGTTTCAATCCCTCATAGGTACGATAAAAACGAATCCGGTGTATAGCATGATGATGCTATTTGGAGTTTCAATCCCTCATAGGTACGATAAAAACCGTGCACCAATCCTTGTGTGATCTCCTGTTGGATGGTAGTTTCAATCCCTCATAGGTACGATAAAAACGGTCTTGAGGCCGGCGACCGGTGATGCATGGTAGAAAAGTTTCAATCCCTCATAGGTACGATAAAAACGCGAAGCATCGCGCCTGAAATTAACGATGTGCTTAGTTTCAATCCCTCATAGGTACGATAAAAACCGAAGCCAAAGCGGTTGACAGCGAGGGCAACGAAAGCGTTTCAATCCCTCATAGGTACGATAAAAACTCGTTGCCTCCGATGAATTGAATGTTGTTGTAGTCGGTTTCAATCCCTCATAGGTACGATAAAAACTTCGCTCAATGCTAGCAGGGGCGACCCCCCAGCGTGTTTCAATCCCTCATAGGTACGATAAAAACCGGAACAATAGCACTGATCGGAACCCCCAGCAAATGTTTCAATCCCTCATAGGTACGATAAAAAC

>NC_014915|6|6|1989131-1991594|CRISPRCasFinder
CGCTTCAGTCCCCACAGGTACGATAAAAAC	GTATTCCTGCACCACGTGATT
GTTTCAATCCCTTATAGTTACGATAAAAAC	AAAATGATCCGGCTAACATTATTCAAGAAGTGAAAAT
GTTTCAATCCTCCATAGGTACGATAAAAAC	GGACAAGCGAGGAGTTGAAAGCATGCGCGACCCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCAATTTTGCCTGGTCGTAGCGGCGGGCGTCAATGTTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGTTTCCGGCTGCGCGAGCTGGGGCGAGATGAAGCC
GTTTCAATCCCTCATAGGTACGATAAAAAC	AAGAAATGCAACGGCATGGTATTGATGTCTCTATTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAATCTTGAACCAGTCCATAAAATAGTTGTCGATCT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATTTTGCCTGGTCGTAGCGGCGGGCGTCAATGTTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	CAGCGTTGGAGCGGTTTTGTCAATGTTCGACACCGCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCGGCAAATCTTCCTTAGCCCTTGCTTCGTCCGGTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGAGTGGAACGAGAGCCGCCGCAATAGCAGGGGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCGATCAAAATACATGAACAATTGGAAACATTTTATCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAGGGAGGATGATTCACTATGACACTTGTCGAAGCTCT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CACTCCCCTTATTGCCCGTCCGATCGTCTCGGGCGGGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTAGGGAGGTTAGAAAAAACAAGGATTGAAAATGAC
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGCCGGATAGCGCCAACAAGACGTCCCGTGTCAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGTTTCGCAACTTGGGCGCCCTCAAACACTACCGAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGTAGAGCGCTATTATGCTGGAAATCCGCCACAACGG
GTTTCAATCCCTCATAGGTACGATAAAAAC	AAGGTACAGGTCAGATTTTCCATCACTACAGCATG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCAAGAGCCATCGCTGACGCTGTTTCTAAAACGAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ACGGCTTCTTTCCAGCAAGCACTTTCAGGTTTTTC
GTTTCAATCCCTCATAGGTACGATAAAAAC	AGTGTTTAGTTCTGATAGATGAAGCAGGTATTATGTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGAACGTTTTGCGATTTATGACAATGAGGGCTATGGGTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCGATCACGCACCAACTCGTAGTCACTTTTCCCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTTTTGCTGTGTTTGGTGTATTTGATGAGTTGCTC
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTATAGCGGCACAGCCTCCGGAAAATTAACTAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCAGCTATACCAGGATATGTTCCCACTGAACTCGGCTGGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTAACGGCATGCGCTCCCACAGATACGGCTTCTCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GAGAGCTAGTGATTTTTACATGTTGCTGTTACAGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GAATCCGGTGTATAGCATGATGATGCTATTTGGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGTGCACCAATCCTTGTGTGATCTCCTGTTGGATGGTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGTCTTGAGGCCGGCGACCGGTGATGCATGGTAGAAAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCGAAGCATCGCGCCTGAAATTAACGATGTGCTTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGAAGCCAAAGCGGTTGACAGCGAGGGCAACGAAAGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCGTTGCCTCCGATGAATTGAATGTTGTTGTAGTCG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTCGCTCAATGCTAGCAGGGGCGACCCCCCAGCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGGAACAATAGCACTGATCGGAACCCCCAGCAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC

>NC_014915|6|4|1989131-1991594|CRT
CGCTTCAGTCCCCACAGGTACGATAAAAAC	GTATTCCTGCACCACGTGATT
GTTTCAATCCCTTATAGTTACGATAAAAAC	AAAATGATCCGGCTAACATTATTCAAGAAGTGAAAAT
GTTTCAATCCTCCATAGGTACGATAAAAAC	GGACAAGCGAGGAGTTGAAAGCATGCGCGACCCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCAATTTTGCCTGGTCGTAGCGGCGGGCGTCAATGTTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGTTTCCGGCTGCGCGAGCTGGGGCGAGATGAAGCC
GTTTCAATCCCTCATAGGTACGATAAAAAC	AAGAAATGCAACGGCATGGTATTGATGTCTCTATTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAATCTTGAACCAGTCCATAAAATAGTTGTCGATCT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATTTTGCCTGGTCGTAGCGGCGGGCGTCAATGTTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	CAGCGTTGGAGCGGTTTTGTCAATGTTCGACACCGCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCGGCAAATCTTCCTTAGCCCTTGCTTCGTCCGGTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGAGTGGAACGAGAGCCGCCGCAATAGCAGGGGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCGATCAAAATACATGAACAATTGGAAACATTTTATCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAGGGAGGATGATTCACTATGACACTTGTCGAAGCTCT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CACTCCCCTTATTGCCCGTCCGATCGTCTCGGGCGGGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTAGGGAGGTTAGAAAAAACAAGGATTGAAAATGAC
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGCCGGATAGCGCCAACAAGACGTCCCGTGTCAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGTTTCGCAACTTGGGCGCCCTCAAACACTACCGAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGTAGAGCGCTATTATGCTGGAAATCCGCCACAACGG
GTTTCAATCCCTCATAGGTACGATAAAAAC	AAGGTACAGGTCAGATTTTCCATCACTACAGCATG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCAAGAGCCATCGCTGACGCTGTTTCTAAAACGAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ACGGCTTCTTTCCAGCAAGCACTTTCAGGTTTTTC
GTTTCAATCCCTCATAGGTACGATAAAAAC	AGTGTTTAGTTCTGATAGATGAAGCAGGTATTATGTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGAACGTTTTGCGATTTATGACAATGAGGGCTATGGGTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCGATCACGCACCAACTCGTAGTCACTTTTCCCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTTTTGCTGTGTTTGGTGTATTTGATGAGTTGCTC
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTATAGCGGCACAGCCTCCGGAAAATTAACTAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCAGCTATACCAGGATATGTTCCCACTGAACTCGGCTGGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTAACGGCATGCGCTCCCACAGATACGGCTTCTCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GAGAGCTAGTGATTTTTACATGTTGCTGTTACAGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GAATCCGGTGTATAGCATGATGATGCTATTTGGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGTGCACCAATCCTTGTGTGATCTCCTGTTGGATGGTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGTCTTGAGGCCGGCGACCGGTGATGCATGGTAGAAAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCGAAGCATCGCGCCTGAAATTAACGATGTGCTTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGAAGCCAAAGCGGTTGACAGCGAGGGCAACGAAAGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCGTTGCCTCCGATGAATTGAATGTTGTTGTAGTCG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTCGCTCAATGCTAGCAGGGGCGACCCCCCAGCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGGAACAATAGCACTGATCGGAACCCCCAGCAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC

>NC_014915|6|4|1989249-1991594|PILER-CR
GTTTCAATCCTCCATAGGTACGATAAAAAC	GGACAAGCGAGGAGTTGAAAGCATGCGCGACCCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCAATTTTGCCTGGTCGTAGCGGCGGGCGTCAATGTTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGTTTCCGGCTGCGCGAGCTGGGGCGAGATGAAGCC
GTTTCAATCCCTCATAGGTACGATAAAAAC	AAGAAATGCAACGGCATGGTATTGATGTCTCTATTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAATCTTGAACCAGTCCATAAAATAGTTGTCGATCT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATTTTGCCTGGTCGTAGCGGCGGGCGTCAATGTTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	CAGCGTTGGAGCGGTTTTGTCAATGTTCGACACCGCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCGGCAAATCTTCCTTAGCCCTTGCTTCGTCCGGTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGAGTGGAACGAGAGCCGCCGCAATAGCAGGGGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCGATCAAAATACATGAACAATTGGAAACATTTTATCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAGGGAGGATGATTCACTATGACACTTGTCGAAGCTCT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CACTCCCCTTATTGCCCGTCCGATCGTCTCGGGCGGGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTAGGGAGGTTAGAAAAAACAAGGATTGAAAATGAC
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGCCGGATAGCGCCAACAAGACGTCCCGTGTCAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGTTTCGCAACTTGGGCGCCCTCAAACACTACCGAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGTAGAGCGCTATTATGCTGGAAATCCGCCACAACGG
GTTTCAATCCCTCATAGGTACGATAAAAAC	AAGGTACAGGTCAGATTTTCCATCACTACAGCATG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCAAGAGCCATCGCTGACGCTGTTTCTAAAACGAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ACGGCTTCTTTCCAGCAAGCACTTTCAGGTTTTTC
GTTTCAATCCCTCATAGGTACGATAAAAAC	AGTGTTTAGTTCTGATAGATGAAGCAGGTATTATGTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGAACGTTTTGCGATTTATGACAATGAGGGCTATGGGTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCGATCACGCACCAACTCGTAGTCACTTTTCCCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTTTTGCTGTGTTTGGTGTATTTGATGAGTTGCTC
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTATAGCGGCACAGCCTCCGGAAAATTAACTAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCAGCTATACCAGGATATGTTCCCACTGAACTCGGCTGGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTAACGGCATGCGCTCCCACAGATACGGCTTCTCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GAGAGCTAGTGATTTTTACATGTTGCTGTTACAGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GAATCCGGTGTATAGCATGATGATGCTATTTGGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGTGCACCAATCCTTGTGTGATCTCCTGTTGGATGGTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGTCTTGAGGCCGGCGACCGGTGATGCATGGTAGAAAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCGAAGCATCGCGCCTGAAATTAACGATGTGCTTA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGAAGCCAAAGCGGTTGACAGCGAGGGCAACGAAAGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCGTTGCCTCCGATGAATTGAATGTTGTTGTAGTCG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTCGCTCAATGCTAGCAGGGGCGACCCCCCAGCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGGAACAATAGCACTGATCGGAACCCCCAGCAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014915.1\|WP_013523955.1\|1977825_1978842_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_014915.1\|WP_013523964.1\|1991776_1992937_-\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NC_014915.1\|WP_013523968.1\|1998854_1999145_-\|UPF0175-family-protein	unknown	unknown	gnl\|CDD\|377095
NC_014915.1\|WP_013523971.1\|2002683_2004393_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226350
NC_014915.1\|WP_013523969.1\|1999640_2001101_-\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143404
NC_014915.1\|WP_013523972.1\|2004606_2005554_-\|aldo/keto-reductase-family-protein	unknown	unknown	gnl\|CDD\|381300
NC_014915.1\|WP_013523958.1\|1981286_1982222_-\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NC_014915.1\|WP_013523966.1\|1993385_1995476_-\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NC_014915.1\|WP_013523963.1\|1988124_1989030_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NC_014915.1\|WP_013523956.1\|1979083_1979605_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271206
NC_014915.1\|WP_013523959.1\|1982281_1982974_-\|response-regulator	unknown	unknown	gnl\|CDD\|226931
NC_014915.1\|WP_013145121.1\|1986210_1986666_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	unknown	unknown	gnl\|CDD\|377815
NC_014915.1\|WP_012820780.1\|1997346_1998225_+\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|372648
NC_014915.1\|WP_013523965.1\|1992936_1993380_-\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NC_014915.1\|WP_013523970.1\|2001302_2002490_-\|iron-containing-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|341473
NC_014915.1\|WP_013523962.1\|1986721_1987762_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270234
NC_014915.1\|WP_013523961.1\|1984670_1986197_-\|tripartite-tricarboxylate-transporter-permease	unknown	unknown	gnl\|CDD\|225870
NC_014915.1\|WP_013523957.1\|1979910_1980837_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NC_014915.1\|WP_013523967.1\|1998358_1998862_-\|DUF3368-domain-containing-protein	unknown	unknown	gnl\|CDD\|225269
NC_014915.1\|WP_013523960.1\|1982987_1984598_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225827

Protein	Function_ID	Function_description	E-value
NC_014915.1\|WP_013523955.1\|1977825_1978842_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.06822e-109
NC_014915.1\|WP_013523964.1\|1991776_1992937_-\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NC_014915.1\|WP_013523968.1\|1998854_1999145_-\|UPF0175-family-protein	gnl\|CDD\|377095	pfam03683, UPF0175, Uncharacterized protein family (UPF0175). This family contains small proteins of unknown function.	2.75843e-16
NC_014915.1\|WP_013523971.1\|2002683_2004393_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|226350	COG3829, RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms].	0
NC_014915.1\|WP_013523969.1\|1999640_2001101_-\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl\|CDD\|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NC_014915.1\|WP_013523972.1\|2004606_2005554_-\|aldo/keto-reductase-family-protein	gnl\|CDD\|381300	cd19074, Aldo_ket_red_shaker-like, Shaker potassium channel beta subunit family and similar proteins. This family includes voltage-gated potassium channel subunits, beta-1 (KCAB1B), beta-2 (KCAB2B) and beta-3 (KCAB3B). KCAB1B and KCAB2B are cytoplasmic potassium channel subunits that modulate the characteristics of the channel-forming alpha-subunits. KCAB3B is an accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. The family also includes Drosophila melanogaster Hk protein, a founding member of aldo-keto reductase family 6 member B1 (AKR6B1), as well as voltage-gated potassium channel subunit beta (KCAB) from Arabidopsis thaliana and Egeria densa, founding members of AKR6C1and AKR6C2, respectively. Hk protein, also called hyperkinetic, is a beta subunit of Shaker (Sh) K+ channels and shows high sequence homology to aldoketoreductase. KCAB, also called Shaker channel b-subunit, or K(+) channel subunit beta, or potassium voltage beta 1, or KV-beta1, or KAB1, is a probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.	0
NC_014915.1\|WP_013523958.1\|1981286_1982222_-\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	8.06261e-32
NC_014915.1\|WP_013523966.1\|1993385_1995476_-\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	6.90885e-66
NC_014915.1\|WP_013523963.1\|1988124_1989030_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	1.31684e-12
NC_014915.1\|WP_013523956.1\|1979083_1979605_+\|hypothetical-protein	gnl\|CDD\|271206	cd14247, Lmo2686_like, Uncharacterized hexameric protein conserved in Bacilli. This family conserved in bacilli contains proteins that form an unusual hexameric arrangement via circular domain-swapping of a beta-hairpin-beta unit.	1.99976e-65
NC_014915.1\|WP_013523959.1\|1982281_1982974_-\|response-regulator	gnl\|CDD\|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.28036e-88
NC_014915.1\|WP_013145121.1\|1986210_1986666_-\|tripartite-tricarboxylate-transporter-TctB-family-protein	gnl\|CDD\|377815	pfam07331, TctB, Tripartite tricarboxylate transporter TctB family. This family consists of several hypothetical bacterial proteins of around 150 residues in length. This family was formerly known as DUF1468.	5.72181e-11
NC_014915.1\|WP_012820780.1\|1997346_1998225_+\|IS982-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	4.52859e-27
NC_014915.1\|WP_013523965.1\|1992936_1993380_-\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	6.08516e-59
NC_014915.1\|WP_013523970.1\|2001302_2002490_-\|iron-containing-alcohol-dehydrogenase	gnl\|CDD\|341473	cd08194, Fe-ADH-like, Iron-containing alcohol dehydrogenases-like. This family contains iron-containing alcohol dehydrogenase (Fe-ADH) most of which have not been characterized. Their specific function is unknown. The protein structure represents a dehydroquinate synthase-like fold and belongs to the alcohol dehydrogenase-like superfamily. It is distinct from other alcohol dehydrogenases which contain different protein domains. Alcohol dehydrogenase catalyzes the reduction of acetaldehyde to alcohol with NADP as cofactor. Its activity requires iron ions.	0
NC_014915.1\|WP_013523962.1\|1986721_1987762_-\|tripartite-tricarboxylate-transporter-substrate-binding-protein	gnl\|CDD\|270234	cd07012, PBP2_Bug_TTT, Bug (Bordetella uptake gene) protein family of periplasmic solute-binding receptors; contains the type 2 periplasmic binding fold. The Bug (Bordetella uptake gene) protein family is a large family of periplasmic solute-binding (PBP) proteins present in a number of bacterial species, but mainly in proteobacteria. In eubacteria, at least three families of periplasmic binding-protein dependent transporters are known: the ATP-binding cassette (ABC) transporters, the tripartite ATP-independent periplasmic transporters, and the tripartite tricarboxylate transporters (TTT). Bug proteins are the PBP components of the TTT. Their expansive expansion in proteobacteria indicates a large functional diversity. The best studied examples are Bordetella pertussis BugD, which is an aspartic acid transporter, and BugE, which is glutamate transporter.	7.81393e-96
NC_014915.1\|WP_013523961.1\|1984670_1986197_-\|tripartite-tricarboxylate-transporter-permease	gnl\|CDD\|225870	COG3333, COG3333, Uncharacterized protein conserved in bacteria [Function unknown].	0
NC_014915.1\|WP_013523957.1\|1979910_1980837_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	1.23038e-15
NC_014915.1\|WP_013523967.1\|1998358_1998862_-\|DUF3368-domain-containing-protein	gnl\|CDD\|225269	COG2405, COG2405, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	6.6005e-33
NC_014915.1\|WP_013523960.1\|1982987_1984598_-\|sensor-histidine-kinase	gnl\|CDD\|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	0

>NC_014915.1|WP_013523963.1|1988124_1989030_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAIDHDRLFKELIQTFFEEFLLLFFPDMHEHIDFSHLSFLSEELFTDVTAGEKYRVDLLVETKLKGEDGLIIVHVENQSYVQPSFPERMFIYFSRLFEKYRTRIVPIAVFSHDTLREEPSVFSIEFPFGDVLQFRFFPVELRKKHWRDYIRHDNPIAAALLGKMGYTESEKIVLKKEFLRMLVRLELDEARQRLLLGFFETYVKLSEEEEQQLQREVKEMETTEKEKMLELIISYEQRGRKQGLEEGVKRGIEQGIKQGMKQGMKQLIRNMARKGMKVEDIARLVDLPEQDVRELLEEQGN
>NC_014915.1|WP_013523962.1|1986721_1987762_-|tripartite-tricarboxylate-transporter-substrate-binding-protein
MKKKRWWGLLAAGMMTLALAACSGNDASGSKSSGSNSGSSASNYPTKPITIVAPSGAGGGWDLTARAITKVLDETGLVKQTMTVENKPGGGGAVFMAEYATQDVKNDYKLFVNSPPIIINNLKKEGNSPFGYKDTTPLAQLTKDFGAIVVKADSKFQSLTQLLDAIKQDPKSVTVAGGSAPGSMDHLVAILPIYKSGIDPKSVKYVSYDGGGEAMAALLGGNADVIATDASSVGEYLKAGKVRVLAVSAPERLGGVLKDVPTMKELGLDAEFTIWRGVFGPKEMSSEAKAFWEETLKKLSEHEKWKEELQKQGWEAEYRNSEEFTKFLKEQEQQIGDLLKSLGMHK
>NC_014915.1|WP_013145121.1|1986210_1986666_-|tripartite-tricarboxylate-transporter-TctB-family-protein
MNKTADRIAAAAFLAVGALFMAESLRLSKSAYGSAVGPNVFPFLLGLVLVFLSIKLLFETRSYSDAAGEKPPRQYKKFLIIFIAAVFYAALLETVGYVITTFLFLVIGFQTMEKGALWKSIAIAAGFSLGVYGLYVKLLQGTLPSWPIWFQ
>NC_014915.1|WP_013523961.1|1984670_1986197_-|tripartite-tricarboxylate-transporter-permease
MSTLSFLLDGFQTALQPHNLLFAFIGVLIGTAVGVLPGIGPMSGVALLIPVTASMTSGLSPEQAAASSIILLAGVYYGAMYGGSTTSILLNTPGESSSVVTTLDGYQMARQGRAGAALAIAAIGSFVAGIVALIGLVLLAEPLSNVALKFGPAEYFSLMLLGLAAVSGLAGKSMTKAWIMTVFGLLLSTIGLDNVSGVARFTYNISYLYGGLEFLTVAVGLFALGEVFKSILHNEMNSGEIAKIGRVLPTKADLRESAGPIARGSLLGFFIGVLPGAGATLASFFSYILEKKISKHPEKFGQGTIAGVAAPESANNGASGGAMIPLLTLGIPGSGTTAILMGALIMYNVQPGPLLFDEHPAVAWGLIASMFIGNVMLLILNMPLVKIFAKIIQTPTKYLLPLIIAISVFGVYAVQVTTFDVFLLLAFGLLGYWLAEHDYPLAPLVLGLVLGPMIENNMRRALTASNGDYLVFFEKPISLVLLVIAFLWIAVPFVVKLRGKSVVINEDM
>NC_014915.1|WP_013523960.1|1982987_1984598_-|sensor-histidine-kinase
MKLQTRLMVIICSLLLLVIVVLTFLFQHMFATTLKQQIGMRALNVAETVASTPLVREAFRDPNPSVRLQPFAEHIRRKTGAEYVVIGNHEGIRYAHPLPDRIGKHMVGGDNGEVLKGKAIISEAVGSLGPAIRGKAPIFDENGHVIGIVSVGFLLEDIQRTVWSYRMKMFLFSVFALFLGAVGAMAIASTVKKSIHGLEPEEIGLLYQEKQAILEAIREGIVAINQEGTITMVNQTALKLLGYENERDVLGMPILQLIPHSRLPEVIRTGQAEFDDEMVLGEETVIANRIPIKDKTGGVIGAVSTFRNKSELYRLTKELSQLRSYADALRAQTHEFSNKLYLISGLIQLESYEEALELIAKETDLQQNIVRFVMKEIPDPIIGGLLIGKFNRANELKIVFEIDRESSFRDVPPWMDRDHLVTIIGNVVDNAMEAVLHNGKEEKRVAIFLTDLGDDLIIEVEDNGLGIDPVVAERIYDRGFSTKAARGRGYGLDLVNRALTMLGGQMTYRSEQGAGTVFTIMIPKRPAHVGRQCRQG
>NC_014915.1|WP_013523959.1|1982281_1982974_-|response-regulator
MLPIRVLIIEDDRRIAEINRRFVEKVNGYEVVGIATNAEEARELTEVLRPDVLLLDVYFPDMNGLSFLKWVREHFSDIDIIMITAAREVDVLKQALHGGVFDYIIKPIMFDRFVETLNRYKEYYDKMQRWVKEKEWIGQEDVDALIGREVSVKDQPMLPKSIQPLTLEKVLAVVRQCPEGITAEEVGRQIGTSRTTARRYLEYLVSIDQVTADITYGSVGRPERVYKKKM
>NC_014915.1|WP_013523958.1|1981286_1982222_-|AEC-family-transporter
MAVFSGILLQVMVPMLLIVGLGAGLHRFFHLDLNTLSKLNMYVLLPAVAFINVYDSELNGKVLAAILGFLLLQNSGLIVLSMMMAKLFKLERSLSAVFQNTIVLNNSGNFGIPVSQLVFHQHPLGATIQIMVTIFQNFLTNTYGVYQFVSGNGKKEKWTAEIWKNPVLHALFLGLVCRWLHVPIPSFLWTPLQRVADAFLAIALFTLGAQIAYARFTALPPLVYVSVFGRLILSPLLAASLIFLLGIDGVTAQALLIASSYPCSRNTALYALEYDCHPDYAAQAVLVSTLLSAITVTGVVYAARLLFPIGG
>NC_014915.1|WP_013523957.1|1979910_1980837_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MARKRIDHDRLFKELLSTFFEEFLLLFFPHVYEHIDVHHLSFLSEELFTDVTAGEKHRVDLLVETKVKGEDGLVIVHVEHQSYTQRTFPERMFLYFSRLFQKYRRRILPIAIFSYDEQYDEPSSLVMQFPFLTVLDFRFLTVELRKQPWRQYIHQDNPVAAALLSKMGYNEEEKVEVKKEFLRMLVRLELDEAKQRLLFGFFETYLRLSEEEEAKLRNEVSQMETKEAKRVMELIVSYEQRGMEKGIQTGIEMGIKQGMKQGMKQGRQQGIEEGKLDVVKRMLAKGYDVDTIHELTGLPVETIEKVKQ
>NC_014915.1|WP_013523956.1|1979083_1979605_+|hypothetical-protein
MVTFTIQEHSHFLYPLFFLCIPILKSQVQLVVKSQKIYNENGEYVGTLGIEPVLSAGSNDNIMSALASYKVGTGNSTWKIYWYSGTVNYHFYVDINIGSTGLATITRAYNGWYFITPPYTVKKDWISILRKTETYTLPAEARYHLTLNSIWGGEWTIYLYARVKDQTLYTGTN
>NC_014915.1|WP_013523955.1|1977825_1978842_-|LacI-family-DNA-binding-transcriptional-regulator
MKKVTMADVAKLANVSKSTVSQYLNKRYEYMSEETRKRIAEAIEELGYQPNVIARSLKQKTTATIGVIVFNMLHMMTTQVLHAIEEECQKRGFQVIVCNSGDDPDKEKTYIETLLAKQVDGMIVFPTGKNEEVYRRLVEERFPLVFVDRMVPGVGADSVLLDNAGAAEMAVQYFASYGYERIAIVTPPLVPYNVPRMERFEGFRAAMEKRGFEVGDQNVIAAEPAALPEVLKQRLAEPKRPNALFAINDLTLMGVLRFVKETGIRMPDELAIINIDDVPFADIYTPALTTIAQPTFAMGKKAAERVFDQMKAKKTDGPRVFRFSPVLMERTSIRRGKA
>NC_014915.1|WP_013523964.1|1991776_1992937_-|mannitol-1-phosphate-5-dehydrogenase
MRAVHFGAGNIGRGFIGSLLAASGYDVVFVDVNEQIVRLLKERGEYRVIVAGEQQEEQWVRGVSALNSQTEREAVIEAIADADLVTTAVGPPILPAIAPVVAAGLQRRFAIQQKPLHVIACENMIAGTEALKTHVFEHLSADEQRLANQSVGFLNCAVDRIVPNQTNDDPLAVTVEPFFEWAIEARNVIGAVPPIQGAHFVADLGPYIERKLFTVNTGHALAAYLGYLRNYETVQEAMNDEDIRWNVEQALSESGAVLVKKHGWDANEHRAYIDTTIGRFMNPSLSDDIIRVARSPIRKLGPNDRLVAPATQYYALFERVPFGLVKGIAALLRFDDASDAEAAALQQTLKQRGVEEALWQYAGLDRGHPLIAAVKEEYGRMEKNKS
>NC_014915.1|WP_013523965.1|1992936_1993380_-|PTS-sugar-transporter-subunit-IIA
MLAHSILNKENIVLNAQPKTKEEAIRLAGEVLVKQGYVDPAYVDAMLEREELTSTYIGNNVAIPHGTEAAKALVKHSGISIVQVPDGVDFGGGNMATIVIGIAGKDGEHLDILSQLALVCAEADHVEAMANAKTEEEILALLHEVNG
>NC_014915.1|WP_013523966.1|1993385_1995476_-|BglG-family-transcription-antiterminator
MYVSARERKLLERLLADDRDITVGELAEELNVSARTVHRDLQGIESVLRRYGLGLAKKAGIGIRLVGEEENKQALAAELFRLSHHEYTPEERQLMIFIALLEANEPVKLVSLATDLNVTVATVSLDLDKVEQTVEAYGLSLIRKRGYGVELAGSESAKRRLMSDLLFRHVDEHEFLALMKETIQKRADAPLDTVAEKLLGLVDRKKLSIIEQQIERVKEKLPFTMADSSYIAFVVHLALAIERIKQGEAIHFDPRDLQALQATKEYEIARVLAESLERAFGIDIPNEEVGYMTMHLMGAKWRSRQGAMMEEPSLAVGMKAQQLIRFVSDKLGVDLSTDRTLYEDLVVHLKPALYRLEHGMGVANPLLDQIKQDYAELFAIVADGARQLFGDIPVPDEEIGYLVLHFAAALMREKKGWRVLVICSSGLGTAKMLATRLKKEIPDIVSLEQASAFEWRGKDVSAYDLVISTVPLPEEYGPHIVVSPMLTEEEARKIRECLERKSAAEKRMEREPTAQRNRPALDIMKAVRRISETIVHILDGFSLAAVTHRSVRELLADACRRLERNGFIVDADVVIEELRRRESLGGLGVPGTTLALYHARSFAVLRPSLTMYRLDSPQTVAGMDGEPMEINTVVLLLGPADADEEMLSVLSHVSTLLVKDEQSAATLAYGGEDEVYSLISGHLEQFFDHYWTSTKE
>NC_014915.1|WP_012820780.1|1997346_1998225_+|IS982-family-transposase
MQEHFHFTTDPAKLQKQYAAIFCFVSAQLSLIQMYLHRRNRHLVKQKDEVVMAVHLLGKLLGFSSERAWHRFVTGNLFTNGSFLERSRYNRRCRALGFAVKWIRHELAKRGQHHAYAVVDSLPLPLCHPARMQRVKRFRGIADMGYCASKKQWYYGFKLHLQVTNQGLAMGYVVTEASCHDVKAAETVMTQIPHPYNFGDKGCISRALREKLYEEHQAAFWTPSRHNQKHGPSKAWEEWIRKKRKVIETVFSILVDQYRITDIRANSIAGFEVALDGILVAYSLVTLGLVER
>NC_014915.1|WP_013523967.1|1998358_1998862_-|DUF3368-domain-containing-protein
MSRVTVNSTPIIGLSIVGQLTLLSELFDEVYVPEAVYQEIVHNHAPRHYGKEELKRLVSEGVFRLYHVKNRSLVESLYGKFHAGELEVIIGAKELGAQVVVMDEHVARSLSKQFFLRPIGTIGVLILGKKNRKIVEVKPLLDTLLENGFYLSQRLYREALSLAEETP
>NC_014915.1|WP_013523968.1|1998854_1999145_-|UPF0175-family-protein
MDYFQVNLPKEFLPAINELEGNTVEAKIKLSLAIGLFVGKQVTLAKAAELAGKSLGEFIDVLRSKAIPWMEYTEEHIKDDWDTVQKLSKENRDHNE
>NC_014915.1|WP_013523969.1|1999640_2001101_-|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
MSSVTETKTLKNFIGGQWVTSTSGKEEIVPNPATGEVLMKVPLSSREELDAAVAAAKEAFREWRKVPVPRRAHILFRYQQLLVEHWEELARLVTLENGKVYEDAYGEVQRGIECVEFAAGIPTLMMGQQLPDIATGIESGMYRYPLGVVAGITPFNFPMMVPCWMFPLAIACGNTFVLKPSERTPMLANRLAELFTEAGLPPGVLNIVHGAHEVVGGILEHKDIKAVSFVGSQPVAEYVYKTAAAHGKRVQALAGAKNHSIVMPDADLDMAVTNIINAAFGSAGERCMACSVVVAVGDIADELVKRLKEAADRIQIGNGLDQGVFLGPVIRESHKERTIKYIEIGEKEGALLVRDGRRDSATSGKGYFIGPTIFDHVKPGMTIWTDEIFAPVLSVVRARDLDEAIEIANRSEFANGACIYTDSAKAIRQFREEIDAGMLGVNVAVPAPMAFFPFSGYKNSFYGDLHANGRDGVEFYTRKKMVTARY
>NC_014915.1|WP_013523970.1|2001302_2002490_-|iron-containing-alcohol-dehydrogenase
MYELLVPSRVVYGRNTFAEVGPQAKALGTKALIVSDPVMEKIGLVARCEQYLQQVGMTFAKYTGVDTEPTDVHVKEALDVCQSEKCDVVIGIGGGSSIDAAKAVAVMMTNEGEIGDYVGNQKRFTEKPLPLIAIPTTAGTGSEVTKVTVIINTKTDVKMMISQPALLPAVAIVDPLLTVSCPPSVTAATGVDALCHAIEAYISRRTHPVTDVLALSAIEAIVGYLRRAYENGEDIEAREKMAIAAMKAGMAFSNASVTLVHGMSRPIGALFHVPHGVSNAMLLPGVLEFTKDSAIERLAVIARIIKPSLKDVSDAEAADALVEEVKQLCRDLRIPNMKTWGIDKAAFDKAVDKMAADALASGSPANNPKVPTHEEIVALYHYCYDYQYDTKTVSS
>NC_014915.1|WP_013523971.1|2002683_2004393_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MASDCSALPTVVCRQALQEVMQLMAARGLESVNVIDEHGRTVGRCTWRMMLRAAADGLDRSMPIGEVLTAFSDKWETKQEGVCVAMPMSESDSKATNELGRLRRELEETHRLAETMKTVLDAAYEGVVVVDEDGVVREINRAYCQFLGIRREEAIGKHVTEVIENTRLHICVQSGIPERGYIQKIYGQPMVVHRIPIWREGKVIGAIGMLIFQGVSEVYEIFRRLQELSREASRKEKKEAKPQETAASAPKGIERIIGRHPAIAAVKQMIRRAARVPSTVLITGESGTGKEVVARAIHEAGPHADGPFVSVNCAAIPESLLEAELFGYEDGAFTGAKKGGKPGKFQLAHGGTLFLDEIGDMPLAMQAKILRALEEKKVEKVGGLYETKVDVRIIAATNKPLEDMVREGTFREDLFYRLNIIRIHLPPLRERKTDIPALLAYHMERICRQFGVALKSFTKEAMEVLVHYSWPGNVRELVNVVEWLISMVEGDVIEREHLPYYLSTVQPAASSLPNGGVKMDDRWKEMVYHSERERIAAALVAAGGNKAEAARRLGIHRSTLYEKLKKYGL
>NC_014915.1|WP_013523972.1|2004606_2005554_-|aldo/keto-reductase-family-protein
MKYRKLGRTGLKVSEISLGSWLTYGNSVEKETAIRVIDKAYELGINSFDTANVYARGEAEKIVGEALRKYPRESYVIATKVFWPMGDGPNDRGLSRKHVFEQLHASLKRLQLDYVDIYYCHRYDKETPVDETLRTIDDLVRQGKVLYVGVSEWTAQQIQEALGVADRYLLDRIVVNQPQYNMFHRYIEKEVIPVCEQNGISQIVFSPLAQGVLTGKYKRGQALPADSRAADPRANTFIQGLLNDEVLTKVEQLEKIAAELGITLSQLALAWVLRQPNVASALIGASRPEQVEENVKAVDVVLSEDVLEKIEGILA

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Crispr_ID: NC_014915_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014915_7

2960188-2961416

Orphan

Consensus_repeat	Method
GTTTCAATCCCTCATAGGTACGATAAAAAC	CRISPRCasFinder
GTTTCAATCCCTCATAGGTACGATAAAAAC	CRT
GTTTTTATCGTACCTATGAGGGATTGAAAC	PILER-CR

18 spacers

The CRISPR arrays of NC_014915_7

>merge|NC_014915|7|2960188-2961416|CRISPRCasFinder,CRT,PILER-CR
ATTTCAATCCCTCATAGGTACGATAAAAACCCCCATTCCGTACATGATTAAACAACTTTCCAAATAGTTTCAATCCCTCATAGGTACGATAAAAACTTTGTGGTGTCGTTCGTTTTCGCAGTAATGAAGAAAGTTTCAATCCCTCATAGGTACGATAAAAACTTTCATCCAGACAACAAGATGGGCAGCTTCTTCGTGAGTTTCAATCCCTCATAGGTACGATAAAAACAGAAGATGAAGACGAAGCACTCGATTTATTTGGCGGGTTTCAATCCCTCATAGGTACGATAAAAACATCATTGACCGACTCGCTCGCTATGAAGCGGACATGTGTTTCAATCCCTCATAGGTACGATAAAAACATGTGTCATTTCAAATCCCCCCTTGGTTTTGTCTTGGGAGTTTCAATCCCTCATAGGTACGATAAAAACGTATTTGAATTTGGCGGAAAAGACTATGCATGGGATAGGTTTCAATCCCTCATAGGTACGATAAAAACACGCTGTCGTACAGTCGTCCGATTTCAAAGAACAGGGTTTCAATCCCTCATAGGTACGATAAAAACGGGAAAAGCCCACCAGACGCGCCAAGGATGACCAAGTTTCAATCCCTCATAGGTACGATAAAAACATTAACATGACCGCTACATACGCAAAAGTATTATAGTTTCAATCCCTCATAGGTACGATAAAAACCCGCAAGAGGGTTTGCGGAAGCACGTTGAACCGGAAAAAGTTTCAATCCCTCATAGGTACGATAAAAACGGCACGACCACCAGCCGAACCATGCCTGTTCAAGTGGTTTCAATCCCTCATAGGTACGATAAAAACGGCGAGGTTCTTCAGCGTGCTTTCTTCGTCCTGTCCAAGTTTCAATCCCTCATAGGTACGATAAAAACGCCAGCCGGAACAGCCACAACAGCAGGATTTGCCTGTTTCAATCCCTCATAGGTACGATAAAAACAGACATCCAAAGAAACAGACGTACGACGCGGAATAGTTTCAATCCCTCATAGGTACGATAAAAACCCCATTGACGATAAAAAGAAACCCGGACGCTCGCAGGGTTTCAATCCCTCATAGGTACGATAAAAACTCATGCGCGCATCCTCCGCTGGTACGCCTAGCGACCGGTTTCAATCCCTCATAGGTACGATAAAAACTCGAATTTTTAAAGGAACTCAAGAAGTCTATACACTGTTTCAATCCCTCATAGGTACGATAAAAACT

>NC_014915|7|7|2960188-2961416|CRISPRCasFinder
ATTTCAATCCCTCATAGGTACGATAAAAAC	CCCCATTCCGTACATGATTAAACAACTTTCCAAATA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTTGTGGTGTCGTTCGTTTTCGCAGTAATGAAGAAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTTCATCCAGACAACAAGATGGGCAGCTTCTTCGTGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	AGAAGATGAAGACGAAGCACTCGATTTATTTGGCGG
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATCATTGACCGACTCGCTCGCTATGAAGCGGACATGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGTGTCATTTCAAATCCCCCCTTGGTTTTGTCTTGGGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTATTTGAATTTGGCGGAAAAGACTATGCATGGGATAG
GTTTCAATCCCTCATAGGTACGATAAAAAC	ACGCTGTCGTACAGTCGTCCGATTTCAAAGAACAGG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGGAAAAGCCCACCAGACGCGCCAAGGATGACCAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATTAACATGACCGCTACATACGCAAAAGTATTATA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCGCAAGAGGGTTTGCGGAAGCACGTTGAACCGGAAAAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCACGACCACCAGCCGAACCATGCCTGTTCAAGTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCGAGGTTCTTCAGCGTGCTTTCTTCGTCCTGTCCAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCCAGCCGGAACAGCCACAACAGCAGGATTTGCCT
GTTTCAATCCCTCATAGGTACGATAAAAAC	AGACATCCAAAGAAACAGACGTACGACGCGGAATA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCCATTGACGATAAAAAGAAACCCGGACGCTCGCAGG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCATGCGCGCATCCTCCGCTGGTACGCCTAGCGACCG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCGAATTTTTAAAGGAACTCAAGAAGTCTATACACT
GTTTCAATCCCTCATAGGTACGATAAAAACT

>NC_014915|7|5|2960188-2961415|CRT
ATTTCAATCCCTCATAGGTACGATAAAAAC	CCCCATTCCGTACATGATTAAACAACTTTCCAAATA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTTGTGGTGTCGTTCGTTTTCGCAGTAATGAAGAAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTTCATCCAGACAACAAGATGGGCAGCTTCTTCGTGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	AGAAGATGAAGACGAAGCACTCGATTTATTTGGCGG
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATCATTGACCGACTCGCTCGCTATGAAGCGGACATGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATGTGTCATTTCAAATCCCCCCTTGGTTTTGTCTTGGGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTATTTGAATTTGGCGGAAAAGACTATGCATGGGATAG
GTTTCAATCCCTCATAGGTACGATAAAAAC	ACGCTGTCGTACAGTCGTCCGATTTCAAAGAACAGG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGGAAAAGCCCACCAGACGCGCCAAGGATGACCAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATTAACATGACCGCTACATACGCAAAAGTATTATA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCGCAAGAGGGTTTGCGGAAGCACGTTGAACCGGAAAAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCACGACCACCAGCCGAACCATGCCTGTTCAAGTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCGAGGTTCTTCAGCGTGCTTTCTTCGTCCTGTCCAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCCAGCCGGAACAGCCACAACAGCAGGATTTGCCT
GTTTCAATCCCTCATAGGTACGATAAAAAC	AGACATCCAAAGAAACAGACGTACGACGCGGAATA
GTTTCAATCCCTCATAGGTACGATAAAAAC	CCCATTGACGATAAAAAGAAACCCGGACGCTCGCAGG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCATGCGCGCATCCTCCGCTGGTACGCCTAGCGACCG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCGAATTTTTAAAGGAACTCAAGAAGTCTATACACT
GTTTCAATCCCTCATAGGTACGATAAAAAC

>NC_014915|7|5|2960189-2961415|PILER-CR
TTTCAATCCCTCATAGGTACGATAAAAACC	CCCATTCCGTACATGATTAAACAACTTTCCAAATAG
TTTCAATCCCTCATAGGTACGATAAAAACT	TTGTGGTGTCGTTCGTTTTCGCAGTAATGAAGAAAG
TTTCAATCCCTCATAGGTACGATAAAAACT	TTCATCCAGACAACAAGATGGGCAGCTTCTTCGTGAG
TTTCAATCCCTCATAGGTACGATAAAAACA	GAAGATGAAGACGAAGCACTCGATTTATTTGGCGGG
TTTCAATCCCTCATAGGTACGATAAAAACA	TCATTGACCGACTCGCTCGCTATGAAGCGGACATGTG
TTTCAATCCCTCATAGGTACGATAAAAACA	TGTGTCATTTCAAATCCCCCCTTGGTTTTGTCTTGGGAG
TTTCAATCCCTCATAGGTACGATAAAAACG	TATTTGAATTTGGCGGAAAAGACTATGCATGGGATAGG
TTTCAATCCCTCATAGGTACGATAAAAACA	CGCTGTCGTACAGTCGTCCGATTTCAAAGAACAGGG
TTTCAATCCCTCATAGGTACGATAAAAACG	GGAAAAGCCCACCAGACGCGCCAAGGATGACCAAG
TTTCAATCCCTCATAGGTACGATAAAAACA	TTAACATGACCGCTACATACGCAAAAGTATTATAG
TTTCAATCCCTCATAGGTACGATAAAAACC	CGCAAGAGGGTTTGCGGAAGCACGTTGAACCGGAAAAAG
TTTCAATCCCTCATAGGTACGATAAAAACG	GCACGACCACCAGCCGAACCATGCCTGTTCAAGTGG
TTTCAATCCCTCATAGGTACGATAAAAACG	GCGAGGTTCTTCAGCGTGCTTTCTTCGTCCTGTCCAAG
TTTCAATCCCTCATAGGTACGATAAAAACG	CCAGCCGGAACAGCCACAACAGCAGGATTTGCCTG
TTTCAATCCCTCATAGGTACGATAAAAACA	GACATCCAAAGAAACAGACGTACGACGCGGAATAG
TTTCAATCCCTCATAGGTACGATAAAAACC	CCATTGACGATAAAAAGAAACCCGGACGCTCGCAGGG
TTTCAATCCCTCATAGGTACGATAAAAACT	CATGCGCGCATCCTCCGCTGGTACGCCTAGCGACCGG
TTTCAATCCCTCATAGGTACGATAAAAACT	CGAATTTTTAAAGGAACTCAAGAAGTCTATACACTG
TTTCAATCCCTCATAGGTACGATAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014915.1\|WP_013144424.1\|2951832_2951997_-\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013524386.1\|2947617_2950035_-\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NC_014915.1\|WP_013524395.1\|2967399_2967996_-\|replication-relaxation-family-protein	unknown	unknown	gnl\|CDD\|379384
NC_014915.1\|WP_013144421.1\|2954664_2955213_+\|gamma-carbonic-anhydrase-family-protein	unknown	unknown	gnl\|CDD\|223735
NC_014915.1\|WP_013524387.1\|2950422_2951622_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NC_014915.1\|WP_015731621.1\|2969401_2969785_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|285278
NC_014915.1\|WP_041468697.1\|2953216_2954299_-\|tetraprenyl-beta-curcumene-synthase-family-protein	unknown	unknown	gnl\|CDD\|378492
NC_014915.1\|WP_013523048.1\|2961523_2962402_+\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|372648
NC_014915.1\|WP_011232317.1\|2952015_2952279_-\|YtzC-family-protein	unknown	unknown	gnl\|CDD\|287677
NC_014915.1\|WP_013524389.1\|2955235_2956447_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NC_014915.1\|WP_013524400.1\|2970220_2970706_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|379617
NC_014915.1\|WP_013524399.1\|2970021_2970228_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NC_014915.1\|WP_013524390.1\|2956909_2958496_+\|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl\|CDD\|236471
NC_014915.1\|WP_013524392.1\|2965339_2965582_-\|DUF2584-domain-containing-protein	unknown	unknown	gnl\|CDD\|371230
NC_014915.1\|WP_013524388.1\|2952571_2953159_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|377744
NC_014915.1\|WP_013144427.1\|2947245_2947560_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NC_014915.1\|WP_013524396.1\|2967943_2969104_-\|cell-division-protein-FtsK	unknown	unknown	gnl\|CDD\|224588
NC_014915.1\|WP_013524391.1\|2964157_2965060_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NC_014915.1\|WP_013524393.1\|2965674_2966463_-\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224423
NC_014915.1\|WP_013524397.1\|2969234_2969405_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_014915.1\|WP_013524396.1\|2967943_2969104_-\|cell-division-protein-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	2.39219e-20
NC_014915.1\|WP_013524386.1\|2947617_2950035_-\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NC_014915.1\|WP_013524395.1\|2967399_2967996_-\|replication-relaxation-family-protein	gnl\|CDD\|379384	pfam13814, Replic_Relax, Replication-relaxation. This family includes proteins which are essential for plasmid replication and plasmid DNA relaxation.	1.39532e-07
NC_014915.1\|WP_013144421.1\|2954664_2955213_+\|gamma-carbonic-anhydrase-family-protein	gnl\|CDD\|223735	COG0663, PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only].	1.58114e-79
NC_014915.1\|WP_013524387.1\|2950422_2951622_-\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.18293e-82
NC_014915.1\|WP_041468697.1\|2953216_2954299_-\|tetraprenyl-beta-curcumene-synthase-family-protein	gnl\|CDD\|378492	pfam10776, DUF2600, Protein of unknown function (DUF2600). This is a bacterial family of proteins. Some members in the family are annotated as YtpB however currently no function is known.	0
NC_014915.1\|WP_013523048.1\|2961523_2962402_+\|IS982-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.88353e-29
NC_014915.1\|WP_011232317.1\|2952015_2952279_-\|YtzC-family-protein	gnl\|CDD\|287677	pfam10732, DUF2524, Protein of unknown function (DUF2524). This family of proteins with unknown function appears to be restricted to Bacillaceae bacteria.	2.29592e-27
NC_014915.1\|WP_013524389.1\|2955235_2956447_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NC_014915.1\|WP_013524400.1\|2970220_2970706_+\|PH-domain-containing-protein	gnl\|CDD\|379617	pfam14470, bPH_3, Bacterial PH domain. Proteins in this family are distantly related to PH domains.	4.94667e-16
NC_014915.1\|WP_013524399.1\|2970021_2970228_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	2.87322e-09
NC_014915.1\|WP_013524390.1\|2956909_2958496_+\|phosphoenolpyruvate-carboxykinase-(ATP)	gnl\|CDD\|236471	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase.	0
NC_014915.1\|WP_013524392.1\|2965339_2965582_-\|DUF2584-domain-containing-protein	gnl\|CDD\|371230	pfam10763, DUF2584, Protein of unknown function (DUF2584). This bacterial family of proteins have no known function.	1.1868e-37
NC_014915.1\|WP_013524388.1\|2952571_2953159_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	3.10991e-73
NC_014915.1\|WP_013144427.1\|2947245_2947560_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	2.07459e-26
NC_014915.1\|WP_013524391.1\|2964157_2965060_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.2014e-17
NC_014915.1\|WP_013524393.1\|2965674_2966463_-\|S9-family-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	5.35767e-51
NC_014915.1\|WP_015731621.1\|2969401_2969785_-\|hypothetical-protein	gnl\|CDD\|285278	pfam08006, DUF1700, Protein of unknown function (DUF1700). This family contains many hypothetical bacterial proteins and putative membrane proteins.	0.00606791

>NC_014915.1|WP_013524390.1|2956909_2958496_+|phosphoenolpyruvate-carboxykinase-(ATP)
MGIANMTNKLDLLLQKPYVHHQLSVAELVEKVLQRNEGRLTHTGAVAVTTGKYTGRSPKDKYIVEEPSTKQTIDWGAVNQPMSPETFDKLYDKVLDYLMKKDELFVFKGFAGADPKYRLPIQVVNEFAWHNLFVHQLFIRPSAEELAAHEPQFTVICAPNFKADPKVDGTRSEAFIIISFERRTVLIGGTEYAGEMKKSIFSVMNYLLPEQGILPMHCSANVGQEGDVALFFGLSGTGKTTLSTDPNRRLIGDDEHGWSSRGIFNIEGGCYAKCINLSREKEPQIFDAIGFGAVLENVVLDDATRVPNYDDGTLTENTRAAYPLQAIQNIIDPSVAGHPSTIVFLTADAFGVLPPISKLTREQAMYHFLSGYTSKLAGTERGVTEPEATFSTCFGAPFLPRPAIEYAEMLGQKIAEHNVRVFLVNTGWTGGPYGVGSRMKLAYTRAMVQAAVEGELDNAETVQDPIFGLAIPTHVPGVPDEVLQPQNTWADKQAYEQKAKELAQKFRANFQKFAHIDPSIEKLGGPLV
>NC_014915.1|WP_013524389.1|2955235_2956447_-|methionine-adenosyltransferase
MSAKRRLFTSESVTEGHPDKICDQISDAILDAILEKDPNARVACETSVTTGLVLVSGEITTSTYVDIPRIVRDTVREIGYTRAKYGFDADTCAVLTSIDEQSPDIAMGVDRALEAREGQMTDEEIEAIGAGDQGLMFGFACNETEELMPLPISLAHRLARRLAEVRKTDVLPYLRPDGKTQVTIEYDENGKPVRVDTIVVSAQHHPEITQEQIQRDIKEQVIEPVVPAELLDENTKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAAGLADKCEVQLAYAIGVARPVSISIDTFGTGKVSEDILIEVVRNNFDLRPAGIIKMLDLRRPIYKQTAAYGHFGRTDIDLPWERTDKAALLKEQALALADK
>NC_014915.1|WP_013144421.1|2954664_2955213_+|gamma-carbonic-anhydrase-family-protein
MIYPYKGKTPQIAASAFIADYVTITGDVVIGEETSIWFNTVIRGDVAPTVIGNRVNIQDNSILHQSPNNPLIIEDGVTVGHQVILHSAIVRKNALIGMGSIILDRAEIGEGAFIGAGSLVPPGKKIPPNTLALGRPAKVVRELTEDDIREMERIRREYVEKGQYYKALQQQRTSCANKKELP
>NC_014915.1|WP_041468697.1|2953216_2954299_-|tetraprenyl-beta-curcumene-synthase-family-protein
MNIPKNPIALMKMVYRDVLPLVHRELAYWRRQAERIPDPELRRQALASIASKTFHCEGGSILALLAGENMEDCIRFIVAYQTISDYLDNLCDRSTSLDPLDFRALHDSMPDALTIGAEPSNYYRHRREQEDGGYLPALVRTCQKVLETVRHYETIAPFLHELAGYYCDLQVHKHVEASERVPRLEKWFAQYKDALPPMEWYEFSACSGSTLGIFCLVAYAFGESLPPEMARQVRDGYFPYIQGLHILLDYLIDQEEDRDGGDLNFCFYYPNETVMLERLCHFIEEADRHVGALPHGEFHRLIHRGLLGLYLSDAKVKKQRGLRRLARRLVRAGGAASQFFYWNGKAYRFWQERQKRLSFS
>NC_014915.1|WP_013524388.1|2952571_2953159_+|class-I-SAM-dependent-methyltransferase
MALMNILPFARFLLDQAVNEGDIAVDATVGNGHDTVYLAERVGETGHVFGFDIQPEAITAASARLAEHGLCGRATLFERSHSELLEALPADVHGRIAGAVFNLGYLPGGNKQIVTQPESTIEAVRQLLSVMKPGGVIVLVVYHGHPEGKRERDALLDYVRSLDQRRVHALKYEFINRQNNPPFLIALENRADGGA
>NC_014915.1|WP_011232317.1|2952015_2952279_-|YtzC-family-protein
MATRQSVEEFLQRCEDVIRYAKEQYTEAQKQEHYNITEYTNAQQMLEQTVIDLAHLARSCNAQQREQLHRMRLQLEQLQNDMILLDR
>NC_014915.1|WP_013144424.1|2951832_2951997_-|hypothetical-protein
MKRRLKQTNPEQKTPSGQNNNDLELGQDFDPVKLAKKQYEETGGQPIRSKQRNG
>NC_014915.1|WP_013524387.1|2950422_2951622_-|MFS-transporter
MPRALWWLLVGMALNVTGASFLWPLNTIYLHEQLGQPLAVAGVVLMLNSGGSVIGSLAGGFLFDRIGGFRVLLAGAVLTMAALAGLSVWHGWPHYAVFLAFVGVGSGVVFPAASAYAGTIWPEGGRRAFNALYVAQNIGVAVGSALGGLVASYSFSLVFFANLLLYAAFLFTVVAGLRRVPLPPRRKKEREGRTGDEASRAHIRALVLLCAGYGLCWLSYVQWSTTIAAYTRELGIPVGQYSLLWTINGALIVLAQPLLSAVIRRFMPTLKRQIVIGFLIFAVSFAMLLGAHSFAEFAASMIVLTIAEMIVWPAIPAAVNEWAPPGKAGFYQGIVNGTATAGRMIGPVIGGSVADLFGMKLLIMMLALFALLAVLAALLHDRRLSKRTENADEKTAASV
>NC_014915.1|WP_013524386.1|2947617_2950035_-|leucine--tRNA-ligase
MSFNHREIEQKWQDYWEKNKTFRTPDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDREINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVINGRSERGGHPVIRKPMRQWMLKITAYADRLLEDLEELDWPESIKEMQRNWIGRSEGAEIEFAVDGHDETFTVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKTGVFTGAYAIHPVTGDRLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVAGGNIEKEAYTGDGEHINSEFLNGLNKQEAIDKMIAWLEEHGKGRKKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTMTPVPEEELPLVLPKTDEIRPSGTGESPLANIEEWVNVVDPKTGKKGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYARFWHKFLYDLGIVPTKEPFQKLFNQGMILGENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLDRVWRLFVTENGELNPNIVDEPANDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEAYKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKLGHTDTIAYEPWPTYDETKLVEDVVEIVVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLVNIVAN
>NC_014915.1|WP_013144427.1|2947245_2947560_-|rhodanese-like-domain-containing-protein
MEEIKEITPAEVKEKLERGEKLNIVDVREDEEVALGMIPGAKHIKMGDIPDRLEEFDRNEEYIFVCRSGRRSENVCRYLQELGYRVRNMTGGMLEWEGETVPKR
>NC_014915.1|WP_013523048.1|2961523_2962402_+|IS982-family-transposase
MQEHFHFTTDPAKLQKQYAAIFCFVSAQLSLIQMYLHRRNRHLVKQKDEVVMAVHLLGKLLGFSSERAWHRFVTGNLFTNGSFLERSRYNRRCRALGFAVKWIRHELAKRGQHHAYAVVDSLPLPLCHPARMQRVKRFRGIADMGYCASKKQWYYGFKLHLQVTNQGLAMGYVVTEASCHDVKAAETVMTQIPHPYNFGDKGYISRALREKLYEEHQAAFWTPSRHNQKHGPSKAWEEWIRKKRKVIETVFSILVDQYRITDIRANSIAGFEVALDGILVAYSLVTLGLVER
>NC_014915.1|WP_013524391.1|2964157_2965060_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAKPRIDHDRLFKELLSTFFEEFLLLFFPNVYEHIDVHRLSFLSEELFTDVTAGEKHRVDLLVETKVKGEDGLVIVHVEHQSYTQRTFPERMFLYFSRLFQKYRRRILPIAIFSYDEHHDEPSSLVVQFPFLTVLDFRFLTVELRKLPWRAYIRHDNPVAAALLSKMGYNEEEKVEVKKEFLRMLVRLELDEAKQRLLFGFFETYLRLSEEEEAKLRNEVSQMETKEAKRVMELIVSYEQRGMEKGIQQGVKQGMKQGRQKGIEEGKLDVVKRMLAKGYDVDTIHELTGLPVEKIERVKG
>NC_014915.1|WP_013524392.1|2965339_2965582_-|DUF2584-domain-containing-protein
MGMPMELQTVIVTKGKEQRVQGNVFVLKKEGYRLYPLDVPLEVRRTVQSEASGVAVVRKLEWEGSRTTVTYELVSLYSTN
>NC_014915.1|WP_013524393.1|2965674_2966463_-|S9-family-peptidase
MDGDIIDQYRFPSPHPGIDVFFVTYMSQGLKVKGFLAVPKQNKVYDGFLYLRGGIKNVGQVRVPRLVQFASQGFVVFAPLYRGNGGGEGNEDFAGDDRYDALAGFHLLRRHPLVHPGRVHMFGFSRGGAMALHAALMAEGVCSVAVWGGVADLELTYWERPDLRRMMKRVIGGTPNKCPERYRHRTPLYHLERLKAPVLIIHGGRDENVSIEHAWRLERRLKQLGKPVTAWYFPEFTHYFPPQANRETVQRLTEWMKQQPTM
>NC_014915.1|WP_013524395.1|2967399_2967996_-|replication-relaxation-family-protein
MKSRLTERQTRILYALNSLQALSRSQIQHMFDLGSKRNANRILQGLREYTHTKRIGEDVYYLNKAGAEMVGGEVTVRRNSPLEHIVMRNDIYIFYHYPHDWKAEAKTRWKEGGKEYSVVSDARFTYQGKMCFLEVDITQKMVENKRKIERYAYLFRFIQRQQLGEPVLLFYTVSQMKKRQIEAITKEYGVHCECLLKA
>NC_014915.1|WP_013524396.1|2967943_2969104_-|cell-division-protein-FtsK
MLEFFLLPLAVGATAVVFGRRRQEDYERDIETAFRHLKVGTTVRDEHVYPKLVAKEKKDLYTRYVYRVPLGLTKKMLEPVKEVLEATLDRYVEVTFKKWLYIDVFHREMPEKVLYKDVPDQNGWVIPLGLNEKGWCFHDFDKTPHCTISGTTRFGKTVMLKNIMTYLIEHHPDDASFVILDMKGGLEFGRYKNLKQVVDVASSPVEAFNVLGKVKVFMEQQEAEFKKNGWSNVVNTPIQKRLFVIVDEGAQLAPDRFMTKEHKDMLAACQHTLGEIARIGGALGIRLIFCTQYPTSDTLPRQVKQNADLKITFRLPTGYASQVAIDDYGAEELPSDIKGRAIIKTHEKMIVQTPLIDDEEMERRLEVYRVEKPAHRTANEDFIRFE
>NC_014915.1|WP_013524397.1|2969234_2969405_-|hypothetical-protein
MIEVIGGGLVLIGIAYAENKGWVDKESVSFILNVGMQAGICGGLLYFIHQLSIWFL
>NC_014915.1|WP_015731621.1|2969401_2969785_-|hypothetical-protein
MEGEGVFQSIFQAYAEHRKRHRKMNEFEYLDQTPYLHSSDYLKELYRGADTKEKKQKLFDYIERFEVGSREYKGYYSLYQRIGKELGHIEDDKEEYIQIPKSLIAEYARQMMDDEDFVKYNMRGQRK
>NC_014915.1|WP_013524399.1|2970021_2970228_+|helix-turn-helix-transcriptional-regulator
MRNRISYLIKARGLKQNHIAQKMGVTEQTFSNWCRNVTQPDLLESYQLSKLLGVPMEELVEEEKEDNG
>NC_014915.1|WP_013524400.1|2970220_2970706_+|PH-domain-containing-protein
MAKLEKLVNLAKEHLEPGEQVVASVLGAYETKIMGKDTVMNGVFLATDRRLVFYGKRTFGGYDLEFFPYENISSTEIGKGLMGHKVSFFASGNKVKMKWIQQGDFDKFINHVKQSIGKKPSSNNAAIASVADELKKFAELKEMGVITEEEFEAKKKQLLGI

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Crispr_ID: NC_014915_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014915_8

2962467-2963956

Orphan

Consensus_repeat	Method
GTTTTTATCGTACCTATGAGGGATTGAAAC	PILER-CR
GTTTCAATCCCTCATAGGTACGATAAAAAC	CRISPRCasFinder
GTTTCAATCCCTCATAGGTACGATAAAAAC	CRT

22 spacers

The CRISPR arrays of NC_014915_8

>merge|NC_014915|8|2962467-2963956|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCCTCATAGGTACGATAAAAACCAACTGTTCGTCTGTCATCAACCCTTTGGACAGTTCCGCGTTTCAATCCCTCATAGGTACGATAAAAACTGTTTCTAAGGTGCCTGACTCTTTTACTCCTTTATGTTTCAATCCCTCATAGGTACGATAAAAACTCCCGGGAAAGTACAAGGCTGTTTATGAAGCCAGCTCAGTTTCAATCCCTCATAGGTACGATAAAAACTGAATTCGTTTTAACTCGAGATTTAGGTCGGTTATTTTGTTTCAATCCCTCATAGGTACGATAAAAACTTTTTATGCCCAATGAGATTTTTGAAGATTTGCAAAGGTTTCAATCCCTCATAGGTACGATAAAAACCTTGGCATGAGCGAGCGGAAATATTATCGGTTGAAGTGTTTCAATCCCTCATAGGTACGATAAAAACCGGCAATTGCGTTGCCGGTACTTGTCCATTTGCGTCGTTTCAATCCCTCATAGGTACGATAAAAACAACCGCGGCAGTGTATCGCTTCCATTCGTCGTCCGGTTTCAATCCCTCATAGGTACGATAAAAACGGCCGTGCCGCTGGCTTTTTGGTGCTGAAGTCGAAGTTTCAATCCCTCATAGGTACGATAAAAACTGAGCGGGTCACTCTCGATGTATTCCCCGCTTGAATGGTTTCAATCCCTCATAGGTACGATAAAAACGGACGAAAGGAGTATTATTTATGAAACTTGAAACATGTTTCAATCCCTCATAGGTACGATAAAAACGGCAAGGTGTCACTGGTCGGGTACTGCGTGCAAAAGAGTTTCAATCCCTCATAGGTACGATAAAAACTGGTATCGTAAACTTCAGTGGCTGATTTGAATTTGGTTTCAATCCCTCATAGGTACGATAAAAACAATGCGGTCGTTGCGGCGCTTGGATGAACGGGAAGGCGTTTCAATCCCTCATAGGTACGATAAAAACGTGCGCTGGGTATTGCGTTTTGTTAGATATATAGATGTTTCAATCCCTCATAGGTACGATAAAAACGCAGTCGCGAGCAGATCATTGTATTGTTGTTCCGTGTTTCAATCCCTCATAGGTACGATAAAAACATCCCCACGCGTAGACTTTACCATCCACCGTCAACGGTTTCAATCCCTCATAGGTACGATAAAAACGGCTCGACGTTCGTGTGGGGCGAGGACGTGACAAAAATGTTTCAATCCCTCATAGGTACGATAAAAACTTGACAATCCGCAGACGGCCAACGCGGAGGGGTTTTTGTTTCAATCCCTCATAGGTACGATAAAAACTAACTTTTTCAAAAATTGGTCATAATGCCGTACTAGGTTTCAATCCCTCATAGGTACGATAAAAACTAGTCTGGGCTCTCCATCATCCCCACCATCCCAACGTTTCAATCCCTCATAGGTACGATAAAAACTACCGAACCACGCCTGTTCAAGTGCAAGGGCTGTCGTTTCAATCCCTCATAGGTACGATAAAAAC

>NC_014915|8|6|2962467-2963956|PILER-CR
GTTTCAATCCCTCATAGGTACGATAAAAAC	CAACTGTTCGTCTGTCATCAACCCTTTGGACAGTTCCGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGTTTCTAAGGTGCCTGACTCTTTTACTCCTTTAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCCCGGGAAAGTACAAGGCTGTTTATGAAGCCAGCTCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGAATTCGTTTTAACTCGAGATTTAGGTCGGTTATTTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTTTTATGCCCAATGAGATTTTTGAAGATTTGCAAAG
GTTTCAATCCCTCATAGGTACGATAAAAAC	CTTGGCATGAGCGAGCGGAAATATTATCGGTTGAAGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGGCAATTGCGTTGCCGGTACTTGTCCATTTGCGTC
GTTTCAATCCCTCATAGGTACGATAAAAAC	AACCGCGGCAGTGTATCGCTTCCATTCGTCGTCCG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCCGTGCCGCTGGCTTTTTGGTGCTGAAGTCGAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGAGCGGGTCACTCTCGATGTATTCCCCGCTTGAATG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGACGAAAGGAGTATTATTTATGAAACTTGAAACAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCAAGGTGTCACTGGTCGGGTACTGCGTGCAAAAGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGGTATCGTAAACTTCAGTGGCTGATTTGAATTTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	AATGCGGTCGTTGCGGCGCTTGGATGAACGGGAAGGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTGCGCTGGGTATTGCGTTTTGTTAGATATATAGAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCAGTCGCGAGCAGATCATTGTATTGTTGTTCCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATCCCCACGCGTAGACTTTACCATCCACCGTCAACG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCTCGACGTTCGTGTGGGGCGAGGACGTGACAAAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTGACAATCCGCAGACGGCCAACGCGGAGGGGTTTTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAACTTTTTCAAAAATTGGTCATAATGCCGTACTAG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAGTCTGGGCTCTCCATCATCCCCACCATCCCAAC
GTTTCAATCCCTCATAGGTACGATAAAAAC	TACCGAACCACGCCTGTTCAAGTGCAAGGGCTGTC
GTTTCAATCCCTCATAGGTACGATAAAAAC

>NC_014915|8|8|2962467-2963956|CRISPRCasFinder
GTTTCAATCCCTCATAGGTACGATAAAAAC	CAACTGTTCGTCTGTCATCAACCCTTTGGACAGTTCCGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGTTTCTAAGGTGCCTGACTCTTTTACTCCTTTAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCCCGGGAAAGTACAAGGCTGTTTATGAAGCCAGCTCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGAATTCGTTTTAACTCGAGATTTAGGTCGGTTATTTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTTTTATGCCCAATGAGATTTTTGAAGATTTGCAAAG
GTTTCAATCCCTCATAGGTACGATAAAAAC	CTTGGCATGAGCGAGCGGAAATATTATCGGTTGAAGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGGCAATTGCGTTGCCGGTACTTGTCCATTTGCGTC
GTTTCAATCCCTCATAGGTACGATAAAAAC	AACCGCGGCAGTGTATCGCTTCCATTCGTCGTCCG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCCGTGCCGCTGGCTTTTTGGTGCTGAAGTCGAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGAGCGGGTCACTCTCGATGTATTCCCCGCTTGAATG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGACGAAAGGAGTATTATTTATGAAACTTGAAACAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCAAGGTGTCACTGGTCGGGTACTGCGTGCAAAAGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGGTATCGTAAACTTCAGTGGCTGATTTGAATTTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	AATGCGGTCGTTGCGGCGCTTGGATGAACGGGAAGGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTGCGCTGGGTATTGCGTTTTGTTAGATATATAGAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCAGTCGCGAGCAGATCATTGTATTGTTGTTCCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATCCCCACGCGTAGACTTTACCATCCACCGTCAACG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCTCGACGTTCGTGTGGGGCGAGGACGTGACAAAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTGACAATCCGCAGACGGCCAACGCGGAGGGGTTTTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAACTTTTTCAAAAATTGGTCATAATGCCGTACTAG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAGTCTGGGCTCTCCATCATCCCCACCATCCCAAC
GTTTCAATCCCTCATAGGTACGATAAAAAC	TACCGAACCACGCCTGTTCAAGTGCAAGGGCTGTC
GTTTCAATCCCTCATAGGTACGATAAAAAC

>NC_014915|8|6|2962467-2963956|CRT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CAACTGTTCGTCTGTCATCAACCCTTTGGACAGTTCCGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGTTTCTAAGGTGCCTGACTCTTTTACTCCTTTAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TCCCGGGAAAGTACAAGGCTGTTTATGAAGCCAGCTCA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGAATTCGTTTTAACTCGAGATTTAGGTCGGTTATTTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTTTTATGCCCAATGAGATTTTTGAAGATTTGCAAAG
GTTTCAATCCCTCATAGGTACGATAAAAAC	CTTGGCATGAGCGAGCGGAAATATTATCGGTTGAAGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	CGGCAATTGCGTTGCCGGTACTTGTCCATTTGCGTC
GTTTCAATCCCTCATAGGTACGATAAAAAC	AACCGCGGCAGTGTATCGCTTCCATTCGTCGTCCG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCCGTGCCGCTGGCTTTTTGGTGCTGAAGTCGAA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGAGCGGGTCACTCTCGATGTATTCCCCGCTTGAATG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGACGAAAGGAGTATTATTTATGAAACTTGAAACAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCAAGGTGTCACTGGTCGGGTACTGCGTGCAAAAGA
GTTTCAATCCCTCATAGGTACGATAAAAAC	TGGTATCGTAAACTTCAGTGGCTGATTTGAATTTG
GTTTCAATCCCTCATAGGTACGATAAAAAC	AATGCGGTCGTTGCGGCGCTTGGATGAACGGGAAGGC
GTTTCAATCCCTCATAGGTACGATAAAAAC	GTGCGCTGGGTATTGCGTTTTGTTAGATATATAGAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	GCAGTCGCGAGCAGATCATTGTATTGTTGTTCCGT
GTTTCAATCCCTCATAGGTACGATAAAAAC	ATCCCCACGCGTAGACTTTACCATCCACCGTCAACG
GTTTCAATCCCTCATAGGTACGATAAAAAC	GGCTCGACGTTCGTGTGGGGCGAGGACGTGACAAAAAT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TTGACAATCCGCAGACGGCCAACGCGGAGGGGTTTTT
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAACTTTTTCAAAAATTGGTCATAATGCCGTACTAG
GTTTCAATCCCTCATAGGTACGATAAAAAC	TAGTCTGGGCTCTCCATCATCCCCACCATCCCAAC
GTTTCAATCCCTCATAGGTACGATAAAAAC	TACCGAACCACGCCTGTTCAAGTGCAAGGGCTGTC
GTTTCAATCCCTCATAGGTACGATAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014915.1\|WP_013144424.1\|2951832_2951997_-\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013524386.1\|2947617_2950035_-\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NC_014915.1\|WP_013524395.1\|2967399_2967996_-\|replication-relaxation-family-protein	unknown	unknown	gnl\|CDD\|379384
NC_014915.1\|WP_013144421.1\|2954664_2955213_+\|gamma-carbonic-anhydrase-family-protein	unknown	unknown	gnl\|CDD\|223735
NC_014915.1\|WP_013524387.1\|2950422_2951622_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NC_014915.1\|WP_015731621.1\|2969401_2969785_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|285278
NC_014915.1\|WP_041468697.1\|2953216_2954299_-\|tetraprenyl-beta-curcumene-synthase-family-protein	unknown	unknown	gnl\|CDD\|378492
NC_014915.1\|WP_013523048.1\|2961523_2962402_+\|IS982-family-transposase	unknown	unknown	gnl\|CDD\|372648
NC_014915.1\|WP_011232317.1\|2952015_2952279_-\|YtzC-family-protein	unknown	unknown	gnl\|CDD\|287677
NC_014915.1\|WP_013524389.1\|2955235_2956447_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235374
NC_014915.1\|WP_013524400.1\|2970220_2970706_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|379617
NC_014915.1\|WP_013524399.1\|2970021_2970228_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NC_014915.1\|WP_013524390.1\|2956909_2958496_+\|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl\|CDD\|236471
NC_014915.1\|WP_013524388.1\|2952571_2953159_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|377744
NC_014915.1\|WP_013524392.1\|2965339_2965582_-\|DUF2584-domain-containing-protein	unknown	unknown	gnl\|CDD\|371230
NC_014915.1\|WP_013524396.1\|2967943_2969104_-\|cell-division-protein-FtsK	unknown	unknown	gnl\|CDD\|224588
NC_014915.1\|WP_013524391.1\|2964157_2965060_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl\|CDD\|273806
NC_014915.1\|WP_013524393.1\|2965674_2966463_-\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224423
NC_014915.1\|WP_013524401.1\|2970771_2971452_-\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|119407
NC_014915.1\|WP_013524397.1\|2969234_2969405_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_014915.1\|WP_013524396.1\|2967943_2969104_-\|cell-division-protein-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	2.39219e-20
NC_014915.1\|WP_013524386.1\|2947617_2950035_-\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NC_014915.1\|WP_013524395.1\|2967399_2967996_-\|replication-relaxation-family-protein	gnl\|CDD\|379384	pfam13814, Replic_Relax, Replication-relaxation. This family includes proteins which are essential for plasmid replication and plasmid DNA relaxation.	1.39532e-07
NC_014915.1\|WP_013144421.1\|2954664_2955213_+\|gamma-carbonic-anhydrase-family-protein	gnl\|CDD\|223735	COG0663, PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only].	1.58114e-79
NC_014915.1\|WP_013524387.1\|2950422_2951622_-\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.18293e-82
NC_014915.1\|WP_041468697.1\|2953216_2954299_-\|tetraprenyl-beta-curcumene-synthase-family-protein	gnl\|CDD\|378492	pfam10776, DUF2600, Protein of unknown function (DUF2600). This is a bacterial family of proteins. Some members in the family are annotated as YtpB however currently no function is known.	0
NC_014915.1\|WP_013523048.1\|2961523_2962402_+\|IS982-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.88353e-29
NC_014915.1\|WP_011232317.1\|2952015_2952279_-\|YtzC-family-protein	gnl\|CDD\|287677	pfam10732, DUF2524, Protein of unknown function (DUF2524). This family of proteins with unknown function appears to be restricted to Bacillaceae bacteria.	2.29592e-27
NC_014915.1\|WP_013524389.1\|2955235_2956447_-\|methionine-adenosyltransferase	gnl\|CDD\|235374	PRK05250, PRK05250, S-adenosylmethionine synthetase; Validated.	0
NC_014915.1\|WP_013524400.1\|2970220_2970706_+\|PH-domain-containing-protein	gnl\|CDD\|379617	pfam14470, bPH_3, Bacterial PH domain. Proteins in this family are distantly related to PH domains.	4.94667e-16
NC_014915.1\|WP_013524399.1\|2970021_2970228_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	2.87322e-09
NC_014915.1\|WP_013524390.1\|2956909_2958496_+\|phosphoenolpyruvate-carboxykinase-(ATP)	gnl\|CDD\|236471	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase.	0
NC_014915.1\|WP_013524388.1\|2952571_2953159_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|377744	pfam06962, rRNA_methylase, Putative rRNA methylase. This family contains a number of putative rRNA methylases. Note that many family members are hypothetical proteins.	3.10991e-73
NC_014915.1\|WP_013524392.1\|2965339_2965582_-\|DUF2584-domain-containing-protein	gnl\|CDD\|371230	pfam10763, DUF2584, Protein of unknown function (DUF2584). This bacterial family of proteins have no known function.	1.1868e-37
NC_014915.1\|WP_013524391.1\|2964157_2965060_-\|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl\|CDD\|273806	TIGR01784, Uncharacterized_protein_pSLT051, conserved hypothetical protein (putative transposase or invertase). Several lines of evidence suggest that members of this family (loaded as a fragment mode model to find part-length matches) are associated with transposition, inversion, or recombination. Members are found in small numbers of genomes, but in large copy numbers in many of those species, including over 30 full length and fragmentary members in Treponema denticola. The strongest similarities are usually within rather than between species. PSI-BLAST shows similarity to proteins designated as possible transposases, DNA invertases (resolvases), and recombinases. In the oral pathogenic spirochete Treponema denticola, full-length members are often found near transporters or other membrane proteins. This family includes members of the putative transposase family pfam04754.	2.2014e-17
NC_014915.1\|WP_013524393.1\|2965674_2966463_-\|S9-family-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	5.35767e-51
NC_014915.1\|WP_013524401.1\|2970771_2971452_-\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|119407	cd02696, MurNAc-LAA, N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino acids in certain cell wall glycopeptides. These proteins are Zn-dependent peptidases with highly conserved residues involved in cation co-ordination. MurNAc-LAA in this family is one of several peptidoglycan hydrolases (PGHs) found in bacterial and bacteriophage or prophage genomes that are involved in the degradation of the peptidoglycan. In Escherichia coli, there are five MurNAc-LAAs present: AmiA, AmiB, AmiC and AmiD that are periplasmic, and AmpD that is cytoplasmic. Three of these (AmiA, AmiB and AmiC) belong to this family, the other two (AmiD and AmpD) do not. E. coli AmiA, AmiB and AmiC play an important role in cleaving the septum to release daughter cells after cell division. In general, bacterial MurNAc-LAAs are members of the bacterial autolytic system and carry a signal peptide in their N-termini that allows their transport across the cytoplasmic membrane. However, the bacteriophage MurNAc-LAAs are endolysins since these phage-encoded enzymes break down bacterial peptidoglycan at the terminal stage of the phage reproduction cycle. As opposed to autolysins, almost all endolysins have no signal peptides and their translocation through the cytoplasmic membrane is thought to proceed with the help of phage-encoded holin proteins. The amidase catalytic module is fused to another functional module (cell wall binding module or CWBM) either at the N- or C-terminus, which is responsible for high affinity binding of the protein to the cell wall.	4.23035e-68
NC_014915.1\|WP_015731621.1\|2969401_2969785_-\|hypothetical-protein	gnl\|CDD\|285278	pfam08006, DUF1700, Protein of unknown function (DUF1700). This family contains many hypothetical bacterial proteins and putative membrane proteins.	0.00606791

>NC_014915.1|WP_013523048.1|2961523_2962402_+|IS982-family-transposase
MQEHFHFTTDPAKLQKQYAAIFCFVSAQLSLIQMYLHRRNRHLVKQKDEVVMAVHLLGKLLGFSSERAWHRFVTGNLFTNGSFLERSRYNRRCRALGFAVKWIRHELAKRGQHHAYAVVDSLPLPLCHPARMQRVKRFRGIADMGYCASKKQWYYGFKLHLQVTNQGLAMGYVVTEASCHDVKAAETVMTQIPHPYNFGDKGYISRALREKLYEEHQAAFWTPSRHNQKHGPSKAWEEWIRKKRKVIETVFSILVDQYRITDIRANSIAGFEVALDGILVAYSLVTLGLVER
>NC_014915.1|WP_013524390.1|2956909_2958496_+|phosphoenolpyruvate-carboxykinase-(ATP)
MGIANMTNKLDLLLQKPYVHHQLSVAELVEKVLQRNEGRLTHTGAVAVTTGKYTGRSPKDKYIVEEPSTKQTIDWGAVNQPMSPETFDKLYDKVLDYLMKKDELFVFKGFAGADPKYRLPIQVVNEFAWHNLFVHQLFIRPSAEELAAHEPQFTVICAPNFKADPKVDGTRSEAFIIISFERRTVLIGGTEYAGEMKKSIFSVMNYLLPEQGILPMHCSANVGQEGDVALFFGLSGTGKTTLSTDPNRRLIGDDEHGWSSRGIFNIEGGCYAKCINLSREKEPQIFDAIGFGAVLENVVLDDATRVPNYDDGTLTENTRAAYPLQAIQNIIDPSVAGHPSTIVFLTADAFGVLPPISKLTREQAMYHFLSGYTSKLAGTERGVTEPEATFSTCFGAPFLPRPAIEYAEMLGQKIAEHNVRVFLVNTGWTGGPYGVGSRMKLAYTRAMVQAAVEGELDNAETVQDPIFGLAIPTHVPGVPDEVLQPQNTWADKQAYEQKAKELAQKFRANFQKFAHIDPSIEKLGGPLV
>NC_014915.1|WP_013524389.1|2955235_2956447_-|methionine-adenosyltransferase
MSAKRRLFTSESVTEGHPDKICDQISDAILDAILEKDPNARVACETSVTTGLVLVSGEITTSTYVDIPRIVRDTVREIGYTRAKYGFDADTCAVLTSIDEQSPDIAMGVDRALEAREGQMTDEEIEAIGAGDQGLMFGFACNETEELMPLPISLAHRLARRLAEVRKTDVLPYLRPDGKTQVTIEYDENGKPVRVDTIVVSAQHHPEITQEQIQRDIKEQVIEPVVPAELLDENTKYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYVAKNIVAAGLADKCEVQLAYAIGVARPVSISIDTFGTGKVSEDILIEVVRNNFDLRPAGIIKMLDLRRPIYKQTAAYGHFGRTDIDLPWERTDKAALLKEQALALADK
>NC_014915.1|WP_013144421.1|2954664_2955213_+|gamma-carbonic-anhydrase-family-protein
MIYPYKGKTPQIAASAFIADYVTITGDVVIGEETSIWFNTVIRGDVAPTVIGNRVNIQDNSILHQSPNNPLIIEDGVTVGHQVILHSAIVRKNALIGMGSIILDRAEIGEGAFIGAGSLVPPGKKIPPNTLALGRPAKVVRELTEDDIREMERIRREYVEKGQYYKALQQQRTSCANKKELP
>NC_014915.1|WP_041468697.1|2953216_2954299_-|tetraprenyl-beta-curcumene-synthase-family-protein
MNIPKNPIALMKMVYRDVLPLVHRELAYWRRQAERIPDPELRRQALASIASKTFHCEGGSILALLAGENMEDCIRFIVAYQTISDYLDNLCDRSTSLDPLDFRALHDSMPDALTIGAEPSNYYRHRREQEDGGYLPALVRTCQKVLETVRHYETIAPFLHELAGYYCDLQVHKHVEASERVPRLEKWFAQYKDALPPMEWYEFSACSGSTLGIFCLVAYAFGESLPPEMARQVRDGYFPYIQGLHILLDYLIDQEEDRDGGDLNFCFYYPNETVMLERLCHFIEEADRHVGALPHGEFHRLIHRGLLGLYLSDAKVKKQRGLRRLARRLVRAGGAASQFFYWNGKAYRFWQERQKRLSFS
>NC_014915.1|WP_013524388.1|2952571_2953159_+|class-I-SAM-dependent-methyltransferase
MALMNILPFARFLLDQAVNEGDIAVDATVGNGHDTVYLAERVGETGHVFGFDIQPEAITAASARLAEHGLCGRATLFERSHSELLEALPADVHGRIAGAVFNLGYLPGGNKQIVTQPESTIEAVRQLLSVMKPGGVIVLVVYHGHPEGKRERDALLDYVRSLDQRRVHALKYEFINRQNNPPFLIALENRADGGA
>NC_014915.1|WP_011232317.1|2952015_2952279_-|YtzC-family-protein
MATRQSVEEFLQRCEDVIRYAKEQYTEAQKQEHYNITEYTNAQQMLEQTVIDLAHLARSCNAQQREQLHRMRLQLEQLQNDMILLDR
>NC_014915.1|WP_013144424.1|2951832_2951997_-|hypothetical-protein
MKRRLKQTNPEQKTPSGQNNNDLELGQDFDPVKLAKKQYEETGGQPIRSKQRNG
>NC_014915.1|WP_013524387.1|2950422_2951622_-|MFS-transporter
MPRALWWLLVGMALNVTGASFLWPLNTIYLHEQLGQPLAVAGVVLMLNSGGSVIGSLAGGFLFDRIGGFRVLLAGAVLTMAALAGLSVWHGWPHYAVFLAFVGVGSGVVFPAASAYAGTIWPEGGRRAFNALYVAQNIGVAVGSALGGLVASYSFSLVFFANLLLYAAFLFTVVAGLRRVPLPPRRKKEREGRTGDEASRAHIRALVLLCAGYGLCWLSYVQWSTTIAAYTRELGIPVGQYSLLWTINGALIVLAQPLLSAVIRRFMPTLKRQIVIGFLIFAVSFAMLLGAHSFAEFAASMIVLTIAEMIVWPAIPAAVNEWAPPGKAGFYQGIVNGTATAGRMIGPVIGGSVADLFGMKLLIMMLALFALLAVLAALLHDRRLSKRTENADEKTAASV
>NC_014915.1|WP_013524386.1|2947617_2950035_-|leucine--tRNA-ligase
MSFNHREIEQKWQDYWEKNKTFRTPDDDDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDREINTTDPNYYKWTQWIFLKLYEKGLAYMDEVPVNWCPALGTVLANEEVINGRSERGGHPVIRKPMRQWMLKITAYADRLLEDLEELDWPESIKEMQRNWIGRSEGAEIEFAVDGHDETFTVFTTRPDTLFGATYTVLAPEHPLVEKITTPEQKPAVDAYLKEIQSKSDLERTDLAKEKTGVFTGAYAIHPVTGDRLPIWIADYVLMSYGTGAIMAVPAHDERDYEFAKKFHLPMKEVVAGGNIEKEAYTGDGEHINSEFLNGLNKQEAIDKMIAWLEEHGKGRKKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTMTPVPEEELPLVLPKTDEIRPSGTGESPLANIEEWVNVVDPKTGKKGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKKWLPVDVYIGGAEHAVLHLLYARFWHKFLYDLGIVPTKEPFQKLFNQGMILGENNEKMSKSKGNVVNPDDIIESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLDRVWRLFVTENGELNPNIVDEPANDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEAYKAEQMKKEYMEGFVKLLSPVCPHIGEELWQKLGHTDTIAYEPWPTYDETKLVEDVVEIVVQINGKVRSRLHVPVDLPKEALEERALADEKIKEQLEGKTVRKVIAVPGKLVNIVAN
>NC_014915.1|WP_013524391.1|2964157_2965060_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MAKPRIDHDRLFKELLSTFFEEFLLLFFPNVYEHIDVHRLSFLSEELFTDVTAGEKHRVDLLVETKVKGEDGLVIVHVEHQSYTQRTFPERMFLYFSRLFQKYRRRILPIAIFSYDEHHDEPSSLVVQFPFLTVLDFRFLTVELRKLPWRAYIRHDNPVAAALLSKMGYNEEEKVEVKKEFLRMLVRLELDEAKQRLLFGFFETYLRLSEEEEAKLRNEVSQMETKEAKRVMELIVSYEQRGMEKGIQQGVKQGMKQGRQKGIEEGKLDVVKRMLAKGYDVDTIHELTGLPVEKIERVKG
>NC_014915.1|WP_013524392.1|2965339_2965582_-|DUF2584-domain-containing-protein
MGMPMELQTVIVTKGKEQRVQGNVFVLKKEGYRLYPLDVPLEVRRTVQSEASGVAVVRKLEWEGSRTTVTYELVSLYSTN
>NC_014915.1|WP_013524393.1|2965674_2966463_-|S9-family-peptidase
MDGDIIDQYRFPSPHPGIDVFFVTYMSQGLKVKGFLAVPKQNKVYDGFLYLRGGIKNVGQVRVPRLVQFASQGFVVFAPLYRGNGGGEGNEDFAGDDRYDALAGFHLLRRHPLVHPGRVHMFGFSRGGAMALHAALMAEGVCSVAVWGGVADLELTYWERPDLRRMMKRVIGGTPNKCPERYRHRTPLYHLERLKAPVLIIHGGRDENVSIEHAWRLERRLKQLGKPVTAWYFPEFTHYFPPQANRETVQRLTEWMKQQPTM
>NC_014915.1|WP_013524395.1|2967399_2967996_-|replication-relaxation-family-protein
MKSRLTERQTRILYALNSLQALSRSQIQHMFDLGSKRNANRILQGLREYTHTKRIGEDVYYLNKAGAEMVGGEVTVRRNSPLEHIVMRNDIYIFYHYPHDWKAEAKTRWKEGGKEYSVVSDARFTYQGKMCFLEVDITQKMVENKRKIERYAYLFRFIQRQQLGEPVLLFYTVSQMKKRQIEAITKEYGVHCECLLKA
>NC_014915.1|WP_013524396.1|2967943_2969104_-|cell-division-protein-FtsK
MLEFFLLPLAVGATAVVFGRRRQEDYERDIETAFRHLKVGTTVRDEHVYPKLVAKEKKDLYTRYVYRVPLGLTKKMLEPVKEVLEATLDRYVEVTFKKWLYIDVFHREMPEKVLYKDVPDQNGWVIPLGLNEKGWCFHDFDKTPHCTISGTTRFGKTVMLKNIMTYLIEHHPDDASFVILDMKGGLEFGRYKNLKQVVDVASSPVEAFNVLGKVKVFMEQQEAEFKKNGWSNVVNTPIQKRLFVIVDEGAQLAPDRFMTKEHKDMLAACQHTLGEIARIGGALGIRLIFCTQYPTSDTLPRQVKQNADLKITFRLPTGYASQVAIDDYGAEELPSDIKGRAIIKTHEKMIVQTPLIDDEEMERRLEVYRVEKPAHRTANEDFIRFE
>NC_014915.1|WP_013524397.1|2969234_2969405_-|hypothetical-protein
MIEVIGGGLVLIGIAYAENKGWVDKESVSFILNVGMQAGICGGLLYFIHQLSIWFL
>NC_014915.1|WP_015731621.1|2969401_2969785_-|hypothetical-protein
MEGEGVFQSIFQAYAEHRKRHRKMNEFEYLDQTPYLHSSDYLKELYRGADTKEKKQKLFDYIERFEVGSREYKGYYSLYQRIGKELGHIEDDKEEYIQIPKSLIAEYARQMMDDEDFVKYNMRGQRK
>NC_014915.1|WP_013524399.1|2970021_2970228_+|helix-turn-helix-transcriptional-regulator
MRNRISYLIKARGLKQNHIAQKMGVTEQTFSNWCRNVTQPDLLESYQLSKLLGVPMEELVEEEKEDNG
>NC_014915.1|WP_013524400.1|2970220_2970706_+|PH-domain-containing-protein
MAKLEKLVNLAKEHLEPGEQVVASVLGAYETKIMGKDTVMNGVFLATDRRLVFYGKRTFGGYDLEFFPYENISSTEIGKGLMGHKVSFFASGNKVKMKWIQQGDFDKFINHVKQSIGKKPSSNNAAIASVADELKKFAELKEMGVITEEEFEAKKKQLLGI
>NC_014915.1|WP_013524401.1|2970771_2971452_-|N-acetylmuramoyl-L-alanine-amidase
MVRIVLDAGHGGHDPGAVANGLREKDLTLAIVKHIGKMLGEYEGAEVHYTRTDDRFLELSERAAIANKLKADLLISVHINAGGGTGFESYIYNGNVSPATIAYQNVIHQELMKAIGNVTDRGKKRANYAVLRETNMPAILTENLFIDNANDAAKLKSEQFLQQVAYGHVQGIVKAFGLKKKAKPQTKQKVSDGKLYRVQVGAFADPENAKRLADELKKKGYPATIV

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Crispr_ID: NC_014915_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014915_9

3047909-3047991

TypeV-U3

Consensus_repeat	Method
ATGGCCACCAAAGACGAACTCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_014915_9

>merge|NC_014915|9|3047909-3047991|CRISPRCasFinder
ATGGCCACCAAAGACGAACTCGCCGAGCTCCGATCCAAAGTGGACGACATCGAAGCGAAAATGGCCACGAAAGACGAACTCGC

>NC_014915|9|9|3047909-3047991|CRISPRCasFinder
ATGGCCACCAAAGACGAACTCGC	CGAGCTCCGATCCAAAGTGGACGACATCGAAGCGAAA
ATGGCCACGAAAGACGAACTCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014915.1\|WP_013524498.1\|3064082_3065375_-\|DnaD-domain-protein	unknown	unknown	gnl\|CDD\|226445
NC_014915.1\|WP_013524489.1\|3045110_3046109_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NC_014915.1\|WP_013144386.1\|3036368_3037538_-\|glucose-1-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|179997
NC_014915.1\|WP_013144384.1\|3040719_3041346_+\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NC_014915.1\|WP_173346441.1\|3037419_3039420_-\|1,4-alpha-glucan-branching-enzyme	unknown	unknown	gnl\|CDD\|235445
NC_014915.1\|WP_013524492.1\|3050197_3050659_-\|tRNA-(N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase-TrmO	unknown	unknown	gnl\|CDD\|187753
NC_014915.1\|WP_013144385.1\|3039638_3040589_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NC_014915.1\|WP_173346442.1\|3042600_3044121_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375438
NC_014915.1\|WP_013144376.1\|3048660_3049203_-\|YobA-family-protein	unknown	unknown	gnl\|CDD\|371575
NC_014915.1\|WP_013524490.1\|3046139_3047081_-\|iron-siderophore-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238566
NC_014915.1\|WP_013524494.1\|3051197_3052406_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_014915.1\|WP_013524483.1\|3035337_3036372_-\|glucose-1-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|273966
NC_014915.1\|WP_011232387.1\|3063028_3063706_+\|MgtC/SapB-family-protein	unknown	unknown	gnl\|CDD\|224204
NC_014915.1\|WP_083777765.1\|3052644_3053088_-\|phage-integrase-N-terminal-SAM-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|274043
NC_014915.1\|WP_013524488.1\|3044137_3045118_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NC_014915.1\|WP_155467743.1\|3048376_3048547_+\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013524496.1\|3061213_3062032_+\|protein-glutamine-gamma-glutamyltransferase	unknown	unknown	gnl\|CDD\|235109
NC_014915.1\|WP_013524486.1\|3041549_3041837_-\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013524493.1\|3050871_3051123_-\|hypothetical-protein	unknown	unknown	unknown
NC_014915.1\|WP_013524497.1\|3062002_3062911_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769

Protein	Function_ID	Function_description	E-value
NC_014915.1\|WP_013524498.1\|3064082_3065375_-\|DnaD-domain-protein	gnl\|CDD\|226445	COG3935, DnaD, Putative primosome component and related proteins [DNA replication, recombination, and repair].	7.28442e-17
NC_014915.1\|WP_013524489.1\|3045110_3046109_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	3.68154e-90
NC_014915.1\|WP_013144386.1\|3036368_3037538_-\|glucose-1-phosphate-adenylyltransferase	gnl\|CDD\|179997	PRK05293, glgC, glucose-1-phosphate adenylyltransferase; Provisional.	0
NC_014915.1\|WP_013144384.1\|3040719_3041346_+\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	4.23589e-40
NC_014915.1\|WP_173346441.1\|3037419_3039420_-\|1,4-alpha-glucan-branching-enzyme	gnl\|CDD\|235445	PRK05402, PRK05402, 1,4-alpha-glucan branching protein GlgB.	0
NC_014915.1\|WP_013524492.1\|3050197_3050659_-\|tRNA-(N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase-TrmO	gnl\|CDD\|187753	cd09281, UPF0066, Escherichia coli YaeB and related proteins. Uncharacterized protein family UPF0066. This domain includes Escherichia coli YeaB, Archeoglobus fulgidus AF0241, and Agrobacterium tumefaciens VirR. Proteins with this domain are probable S-adenosylmethionine-dependent methyltransferases but they have not been functionally characterized and the substrate is unknown.	5.10759e-47
NC_014915.1\|WP_013144385.1\|3039638_3040589_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.67259e-100
NC_014915.1\|WP_173346442.1\|3042600_3044121_-\|hypothetical-protein	gnl\|CDD\|375438	pfam17936, Big_6, Bacterial Ig domain. This domain is found in a wide variety of extracellular bacterial proteins often in multiple tandem copies.	3.12271e-08
NC_014915.1\|WP_013144376.1\|3048660_3049203_-\|YobA-family-protein	gnl\|CDD\|371575	pfam11518, DUF3221, Protein of unknown function (DUF3221). This family of proteins with unknown function appears to be restricted to Bacillus. Some members in this family of proteins are annotated as YobA however this cannot be confirmed. YobA is a protein with unknown function.	1.3954e-21
NC_014915.1\|WP_013524490.1\|3046139_3047081_-\|iron-siderophore-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238566	cd01146, FhuD, Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA-like protein is comprised of two globular subdomains connected by a long alpha helix and binds its specific ligands in the cleft between these domains.	1.16208e-62
NC_014915.1\|WP_013524483.1\|3035337_3036372_-\|glucose-1-phosphate-adenylyltransferase	gnl\|CDD\|273966	TIGR02092, Glycogen_biosynthesis_protein_GlgD, glucose-1-phosphate adenylyltransferase, GlgD subunit. This family is GlgD, an apparent regulatory protein that appears in an alpha2/beta2 heterotetramer with GlgC (glucose-1-phosphate adenylyltransferase, TIGR02091) in a subset of bacteria that use GlgC for glycogen biosynthesis. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	3.67419e-143
NC_014915.1\|WP_011232387.1\|3063028_3063706_+\|MgtC/SapB-family-protein	gnl\|CDD\|224204	COG1285, SapB, Uncharacterized membrane protein [Function unknown].	6.68956e-56
NC_014915.1\|WP_083777765.1\|3052644_3053088_-\|phage-integrase-N-terminal-SAM-like-domain-containing-protein	gnl\|CDD\|274043	TIGR02225, Tyrosine_recombinase_XerD, tyrosine recombinase XerD. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerD, one of two closely related chromosomal proteins along with XerC (TIGR02224). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and with homologs of XerD on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerD, as some apparent XerD examples score below the trusted and noise cutoff scores. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	1.38248e-11
NC_014915.1\|WP_013524488.1\|3044137_3045118_-\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	1.48499e-92
NC_014915.1\|WP_013524496.1\|3061213_3062032_+\|protein-glutamine-gamma-glutamyltransferase	gnl\|CDD\|235109	PRK03187, tgl, transglutaminase; Provisional.	5.92952e-159
NC_014915.1\|WP_013524497.1\|3062002_3062911_-\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.09737e-18
NC_014915.1\|WP_013524494.1\|3051197_3052406_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	8.11172e-43

>NC_014915.1|WP_013524490.1|3046139_3047081_-|iron-siderophore-ABC-transporter-substrate-binding-protein
MLQKKWTSLLAVLMALFVLLVPLAQPAAPVEAASKTRVFKTELGKLVIKGTPKRIVTLSMAGTDAVVTLGLKPVGYTISNSGTVPTYLRNKLKGVPSVGALSAPSLERIAALKPDLIIIDHEFEFHKAIIPQLKKIAPVAGFRANSYKEAMNQLLVLGDILGRKAKAKSFVNQFYKELKSQQAKLKDKNLRVLGFFVNKDGINVWQDNSFSGSIFTALKADYAFKEKGDEYSDFKTVSLERILEIDPDVLFAYTDPGKNDLKKVKANPIWSQLKAVKKKRVVEVNRDLWSRSRGPLAAKLIVKEAASILKRYQ
>NC_014915.1|WP_013524489.1|3045110_3046109_-|iron-ABC-transporter-permease
MTYGKKAIWISVIAGLGIVLLMIVSLVSGPFFVPIPKVLDVLLHDDGSKARTVVWNLRFPRALLAVLIGANLAVAGAMMQCLTKNPMAEPKIMGVSAGAAAMVVLIEYFFAGLPLLFFSPLVFLGAAVGGALVYSLSLKRGTLSPVRLTLAGVAVSAFLHAITVGILVLLGQDAAAVYAWLAGGLNGLTWRHVSLIAPWSLAGLLLSIMIASKMDLLELGDDTAKGLGVHVGILKTVMAVMIIILAGSAVSVSGVIGFIGLIIPHIVRKMVGVNYTYIVPVSALCGGMLLLTADLLARLAAQPIELPVGVFTAAIGCPYFLYLIRKQGEWNA
>NC_014915.1|WP_013524488.1|3044137_3045118_-|iron-ABC-transporter-permease
MRKRDVGLVAGLALLLVIIVPLGACFGDVKIPVSQVWEAFFNRKSSLNGEIVWEYRLPRILVGLFVGANLAVSGALLQAVTQNPLAAPNVIGMTAGASLFAVLALLIIPHFPVSGLPFVTFFGALFAGLCVYAFAWKKGMDKGRFALSGIAFDALFQAVITGILVFATKGIDAAVIWLAGSLWGRTWEHVFLIAPWSVVGLGLAYLCYRRMNVLQLHDDVAASLGMRVQAARFLIFLIAVGLCGSAVAVSGPIGFLGLVIPHLARLLTRADYQLLIPVSALLGAILMISADTAGRTIAAPIEIPVGILTAFIGAPYFLFLLRRAKL
>NC_014915.1|WP_173346442.1|3042600_3044121_-|hypothetical-protein
MSWKTWMVSSFAAVSLAIAGAAESEAYAAKPAKLAIESAQPVNASTVKEYIVKGKGLKGAKIKIVITDGKASVTHDTVVQKSGSFEAPVNVSTLRDGTLTVSVTQIIKGQKHSRVQKKIIKDTKAPSVPVITNKGWINAKQQNAYAVQGTAEPHSAVQVLLSDGKQRITKTVRADGKGRFRAVIDARRLAEGEITVSAVSVDSAGNQSGQSKKVLRKDVSIEAPELLNEGYINAFNYEAYPVTGTGTPGEKVVVEADDGKKSVSASGLVDEDGNYEVEINTSSLKDGKITIRVKTIDQAGNESRMASVVLIKSLSSPAKPSIDNKGYVNAGADATAYEVTGKGEPGAEVEVTLSDGTNEISTVGTVEENGRYRVEADISPLSDGLITITAVQTSVTGNVSPEATATVWKDTAVAAPSLNALPAVTSQNQAAYTIAGTAESNALVQVIITDGQKSLVERTSADSNGNFSKTIDLSAFNNGQLIIIVTQEDKAQNHSEATTATVTKGQ
>NC_014915.1|WP_013524486.1|3041549_3041837_-|hypothetical-protein
MSAGRSLDEHFLPFYCAGLRFGAAVGVTRRENVRDKGMRLLPLGVRLMKPQREQYKRMAACERKAAMLVLVEMPNLLSFGPDVLLFLPLFLLEGL
>NC_014915.1|WP_013144384.1|3040719_3041346_+|LysE-family-translocator
MGIGTIFSFLGVAVLLTLAPGPDILFVIAQSLSQGKQAGIATALGLCTGLLVHISAATLGVSAVIYQSALAFAIVKYAGAAYLLYLAWQAFREKDSSLAFGRQKPMAYASLYKKGIVMNVLNPKVSLFFLALLPQFVDPSAGRVPQQMLLLGAVFLAQALAVFTLVSIGAEKLRHWLLANTAITKRIHWLKGAIFALIGIQIAFSERS
>NC_014915.1|WP_013144385.1|3039638_3040589_+|cation-transporter
MAPTLYDFHHLPHVKTQNESKKALWVTLLLTMFFTAVEIIGGLISNSLALLSDSAHMASDVLALGLSMVALYMATRPPNRRFTFGFLRFEIITSFLNGLTLAVIALWILWEGIQRFLHPEPINFRLMLGIAAIGLVVNLTLTIVLSRSTKEEDNLNVQSALWHFIGDLISSIGVIVSALLIYFTGWTVFDPIISLVIAAIIFTGGAKIMRESYLILMEAVPDGFDLEQIRADIRKIEGVEDVHDMHLWAISTDHYSLSAHVFVNERIQPLCVILAVNEMLKEKYGIEHATIQVEHAMLHDHGRYGRAFLEKKASHE
>NC_014915.1|WP_173346441.1|3037419_3039420_-|1,4-alpha-glucan-branching-enzyme
MIAANPTDLEVYLFHEGRLYQSYELFGAHVIRDGGAVGTRFCVWAPHAREVRLVGSFNDWNGANSPLTKVNDEGVWTIVVPENLEGHLYKYEIITPDGRVLLKADPYAFYSELRPHTASIVYDLKGYEWNDSSWQRKKRRKRIYDQPMVIYELHFGSWKKKPDGRFYTYREMADELIPYVLERGFTHIELLPLVEHPLDRSWGYQGTGYYSVTSRYGTPHDFMYFVDRCHQAGLGVIIDWVPGHFCKDAHGLYMFDGAPTYEYANEKDRENYVWGTANFDLGKPEVRSFLISNALFWLEYYHVDGFRVDAVANMLYWPNNDRLYENPYAVEFLRQLNEAVFAYDPNVLMIAEDSTDWPRVTAPTYDGGLGFNYKWNMGWMNDMLKYMETPPHERKYAHNQVSFSLLYAYSENFILPFSHDEVVHGKKSLLNKMPGSYEEKFAQLRLLYGYMMAHPGKKLLFMGSEFAQFDEWKFEGELDWVLFDFELHRKMDEYVKQLIACYKRYKPFYELDHDPRGFEWIDVHNAEQSIFSFVRRGKKDGDLLVIVCNFTNQAYDDYKVGVPLLAPYREVLNSDAAEFGGSGHVNGKRLPAFSEPFHGKPYHVRMTIPPFGISILRPVQKRGERKQNEEEVHRHVIGRRARKPASLADEKHRETSRAVWGEVPDH
>NC_014915.1|WP_013144386.1|3036368_3037538_-|glucose-1-phosphate-adenylyltransferase
MKKKCIAMLLAGGQGSRLRSLTKNIAKPAVPFGGKYRIIDFTLSNCTNSGIDTVGVLTQYQPLLLHSYIGIGSAWDLDRRNGGVTVLPPYSASSGVKWYEGTANAIYQNMNYIEQYDPDYVLVLSGDHIYKMDYQQMLDYHIAKQADATISVIEVPWEEASRFGIMNTNENMEIVEFAEKPANPKSNLASMGIYIFNWPLLREYLQIDNADPHSSHDFGKDVIPRLLRENKRLVAYPFKGYWKDVGTVKSLWEANMDLLDEHNELDLFDRSWRIYSVNPNQPPQYIAPEAEVSDSLINEGCVVEGTVERSVLFQGARIGKGAVVKESVIMPGATVGEGAYVERAIVTPEIVIPPHSTVSPGDADDDVVLVTTEWIKQRNKDTARKDGAQ
>NC_014915.1|WP_013524483.1|3035337_3036372_-|glucose-1-phosphate-adenylyltransferase
MNNNMMLGVIDATTYMEAMAPLVEQRSIAAVPFAGRYRLIDFVLSSMVNSGIESVAIFPKYQYRSLMDHLGSGKNWDLNRKRDGLFFFPSPDLLFSGERRVGAFAHFEQHIDYFLRSRQKYAVIANSYTVCNIDFDAVLERYIERGCDVTRVCHRGEPLEMYVLETSLLLDLISVYKERGYRSIVDVVCDDCHSLSICDYEYSGYADVIDSLARYFQASMELLDRSVWEQLFLPSRPIYTKVKDEPPTKYRREGNVKRSMIANGCVIEGTVENSVLFRSVKIGKGAVVKNSIVMQKCQIGDGCVLDGVIVDKDAKIEPGVVLQGTAERPFVVRKGTVQGEVVNR
>NC_014915.1|WP_155467743.1|3048376_3048547_+|hypothetical-protein
MYDEYPNCYFVYAYGDNGAVYSMVLAKCLRDWIAAGQSDNAQLYLPDRPLVSALSS
>NC_014915.1|WP_013144376.1|3048660_3049203_-|YobA-family-protein
MRLMITKEEEIGLKRWLAFIAAVWSVWLAGCSGQTDRYAIEGYVVRKEGGSILVVSSDPQDFRSTGGLKEFYNAILVSSAPARVNIGQKVQVWIDGGIAESYPGQGKAGKVLVVPSSPRDGASLSEEEAIRQALKQEESRLEHMIPVIRAVHYDKQADTWMIQIKDAHERTEFDVRIKDE
>NC_014915.1|WP_013524492.1|3050197_3050659_-|tRNA-(N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase-TrmO
MQYTITPIAFVKNNRKDVEDDNWGSVISIIELSDEIDDSALQGISEFSHLDIIFYFDRVTDDKIQYGARHPRNNKEYPKVGIFAQRGKNRPNKLGLTTVELLEHKGRTLKVRGLDAIDGTPIIDIKPVMKEFLPKGEVRQPAWSVSLMERYWD
>NC_014915.1|WP_013524493.1|3050871_3051123_-|hypothetical-protein
MLIGVFRIEHLLLLQEKINVYLSFIESGEIYTTYTPSKGRKFEIKICFKESIPDSCILFLQQASKIIADAGFFLTYSVGLENE
>NC_014915.1|WP_013524494.1|3051197_3052406_-|IS110-family-transposase
MRVLYERCCGLDVHKKSITACVLTPEGKEIRTFGTMTDDLEELVEWLKQKQVTHVAMESTGVYWKPIYNLLEAEPIDVLVVNAQHLKAVPGRKTDVKDAEWIADLLRHGLLIPDRAQRELRELVRYRRSLIEERAREFNRIQKVLEGANIKLASVVSDISGVSAQQILRALIEGTDDSAVLAQLAKGRLKQKIGELRRALKGIMGPHQRMMLSEQCRHIEYLDEAIARLSREIEERTRPFHEALELMETIPGVGRQSAEQIIAEIGTDMSRFPTAAHLASWAGMAPGNHESAGKRLSGRTRKGNKKLRACLVECARAAARTKNTYLSAKYHRIAKRRGANRASVAVGRTILEIIYSVLTRKEPYRELGADYWDQQREAAIVRQTVKRLEGLGYEVKLEKTSA
>NC_014915.1|WP_083777765.1|3052644_3053088_-|phage-integrase-N-terminal-SAM-like-domain-containing-protein
MGRIENERELQRKSKRGRRGELSREELLLISDDIREIEYTFEELLEIFIEDCELRNLREHTIKYYRSELNAFVKLLKEQEIELRVSEWTGETIKRNVIMYMKEKGLKTVSINSRLRAMRAFFNFLEGRNLIKSNPMKDIKLLKDRLP
>NC_014915.1|WP_013524496.1|3061213_3062032_+|protein-glutamine-gamma-glutamyltransferase
MIRVLSPINFDVSSSFSLPASEQRILDALVSSPKLYTYANKHQLRFEIALRDRIVRAAGELAKSRARFAIFRFSRCNSDFWTRDERGGFRLRPDVTASEAIQDIFVHSERYAFECATAIVIVFYKAVLDVIDPAAFNRLFADLLLYDWHTDRDLGIQTKKDEHFLPGDCLYFKNPEFDPLTPQWQGENAIYLGDGFFYGHGIGIQTADGIIAALNRKRKRGATKSAYLLPDITQVDFAYLSQFARGFDEFRLPIRRPPFIVGTLGSATFLLR
>NC_014915.1|WP_013524497.1|3062002_3062911_-|DMT-family-transporter
MKPPSTIKAYAALFIGALAVSTSAIFVKWSQAPSAVIAFYRLFLAVAIMTPLFLRHRSELRGISRRDWLFSLCSGVLLAFHFILWFESLDYTSVASSVVLVTLQPLFAFAGGALFFRERLTVGAVGSAVLAMIGSVLISWGDFRVSGEALYGDGLALLSCAFVTAYWLFGQEVRQRLSLMTYTYIVYSISAAVLWLYAMLFRLSLTAYQLTDWLCFLALAVIPTLLGHSVMNWAVKWVSASTVSMAILFEPIGASALAYWLFGEPIRPFQWIGGIFILTGIALYLWEKNEKGPLTEQERSGP
>NC_014915.1|WP_011232387.1|3063028_3063706_+|MgtC/SapB-family-protein
MMFDPFLKLGISAILGLIIGLERELKRKPVGLKTCLVISISSCLLTIVSIESAYVFPLKDHITMDPLRLAAQIVSGVGFLGAGVILRRGNDSITGLTTAAIIWGAAGIGVAVGAGFYWESAFGVALLIVSVELIPFLINFFGPKQLREKEVLLQITVADAKNITKVIDHLKQQDINIKTMRIKDVEENEHLLKLRAVIDQKRSTAELYYVIRSIDDVVHVDIESG
>NC_014915.1|WP_013524498.1|3064082_3065375_-|DnaD-domain-protein
MSNLLFDDQPLVILPQLALAIGLNESIVVQQLHYWLKKSENVHDGYKWVYNTYADWQQQFPFWSESTVRRTITKLEKMGIIVAANFNRSKIDKTKWYRIDYDKLAEITKEMSEMSGGEHGQAADDGVMTANGVSIVPDAFSFTQDGASFVHDEGLTTHGGDSIVQDGVSAVQGGASVVHGEVLASGTSTAQNKVLAMEERGSMRLSSVSMIQQHPISAVCDGVSTGQNEQTMGETVRPFAQNEPSNWSNWAVKALNLTRPIPETTTEMTAEIKKEDEEDARVRTYKEIVRFCEENGFGVIGDYLREKINAWVDDASEELVLEALKIAVENGAKRWVYVETILRDWTEKGYRTVDEVRAARLAFREQRMKQRSAPPSSDGGRTMRKPIRTEIVPDWLNMDYSQPEDDDFDVEQARRELEERLKKYKTNPDG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_014915_3	3.20\|364790\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	364790-364824	35	NC_014915.1	3001657-3001691	0	1.0
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NC_014915.1	1608906-1608939	0	1.0

1. spacer 3.20|364790|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to position: 3001657-3001691, mismatch: 0, identity: 1.0

aaggaggtgatagaagtgacaaaagaagagattgt	CRISPR spacer
aaggaggtgatagaagtgacaaaagaagagattgt	Protospacer
***********************************

2. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to position: 1608906-1608939, mismatch: 0, identity: 1.0

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggcccggcttgtcggagatgaccgttgtaaacg	Protospacer
**********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014915_1	1.5\|339674\|37\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	339674-339710	37	NC_008376	Geobacillus phage GBSV1, complete genome	12394-12430	0	1.0
NC_014915_1	1.10\|340007\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	340007-340041	35	NC_009552	Geobacillus virus E2, complete genome	30417-30451	0	1.0
NC_014915_1	1.22\|340804\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	340804-340838	35	NZ_AP022559	Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence	33083-33117	0	1.0
NC_014915_2	2.23\|351214\|36\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	351214-351249	36	NC_008376	Geobacillus phage GBSV1, complete genome	25202-25237	0	1.0
NC_014915_2	2.30\|351680\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	351680-351714	35	NC_019544	Deep-sea thermophilic phage D6E, complete genome	13841-13875	0	1.0
NC_014915_3	3.1\|363522\|38\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	363522-363559	38	NC_009552	Geobacillus virus E2, complete genome	30517-30554	0	1.0
NC_014915_3	3.7\|363922\|38\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	363922-363959	38	NC_019544	Deep-sea thermophilic phage D6E, complete genome	11374-11411	0	1.0
NC_014915_3	3.15\|364460\|36\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	364460-364495	36	NC_019544	Deep-sea thermophilic phage D6E, complete genome	3362-3397	0	1.0
NC_014915_3	3.20\|364790\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	364790-364824	35	NZ_AP022559	Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence	37215-37249	0	1.0
NC_014915_6	6.31\|1991131\|38\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1991131-1991168	38	NC_019544	Deep-sea thermophilic phage D6E, complete genome	6054-6091	0	1.0
NC_014915_8	8.8\|2962967\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	2962967-2963001	35	NC_019544	Deep-sea thermophilic phage D6E, complete genome	35536-35570	0	1.0
NC_014915_8	8.8\|2962967\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	2962967-2963001	35	NC_009552	Geobacillus virus E2, complete genome	31006-31040	0	1.0
NC_014915_8	8.9\|2963032\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	2963032-2963066	35	NC_019544	Deep-sea thermophilic phage D6E, complete genome	5144-5178	0	1.0
NC_014915_1	1.10\|340007\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	340007-340041	35	NC_019544	Deep-sea thermophilic phage D6E, complete genome	34947-34981	1	0.971
NC_014915_1	1.20\|340669\|38\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	340669-340706	38	NZ_AP022559	Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence	39780-39817	1	0.974
NC_014915_2	2.36\|352076\|34\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	352076-352109	34	NC_019544	Deep-sea thermophilic phage D6E, complete genome	5239-5272	1	0.971
NC_014915_3	3.6\|363854\|38\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	363854-363891	38	NC_019544	Deep-sea thermophilic phage D6E, complete genome	11305-11342	1	0.974
NC_014915_3	3.20\|364790\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	364790-364824	35	NC_009552	Geobacillus virus E2, complete genome	24263-24297	1	0.971
NC_014915_6	6.28\|1990936\|36\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1990936-1990971	36	NZ_CP015439	Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_1, complete sequence	200603-200638	1	0.972
NC_014915_6	6.30\|1991067\|34\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1991067-1991100	34	NC_019544	Deep-sea thermophilic phage D6E, complete genome	42513-42546	1	0.971
NC_014915_1	1.24\|340934\|37\|NC_014915\|CRISPRCasFinder,CRT	340934-340970	37	NZ_AP022559	Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence	29722-29758	2	0.946
NC_014915_2	2.4\|349933\|37\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	349933-349969	37	NC_019544	Deep-sea thermophilic phage D6E, complete genome	11549-11585	2	0.946
NC_014915_2	2.8\|350203\|38\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	350203-350240	38	NZ_AP022558	Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence	42458-42495	2	0.947
NC_014915_3	3.17\|364592\|36\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	364592-364627	36	NC_019544	Deep-sea thermophilic phage D6E, complete genome	5078-5113	2	0.944
NC_014915_3	3.22\|364924\|37\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	364924-364960	37	NZ_AP022558	Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence	104509-104545	2	0.946
NC_014915_3	3.25\|365124\|36\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365124-365159	36	NZ_AP022559	Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence	29779-29814	2	0.944
NC_014915_6	6.20\|1990406\|35\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1990406-1990440	35	NC_009552	Geobacillus virus E2, complete genome	12343-12377	2	0.943
NC_014915_6	6.34\|1991332\|37\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1991332-1991368	37	NZ_AP022558	Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence	52079-52115	2	0.946
NC_014915_7	7.2\|2960284\|36\|NC_014915\|CRISPRCasFinder,CRT	2960284-2960319	36	NZ_AP022558	Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence	4007-4042	2	0.944
NC_014915_7	7.20\|2960285\|36\|NC_014915\|PILER-CR	2960285-2960320	36	NZ_AP022558	Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence	4007-4042	2	0.944
NC_014915_8	8.22\|2963892\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	2963892-2963926	35	NZ_AP022558	Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence	53808-53842	2	0.943
NC_014915_8	8.22\|2963892\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	2963892-2963926	35	NZ_AP022558	Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence	53958-53992	2	0.943
NC_014915_6	6.6\|1989478\|36\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1989478-1989513	36	NZ_AP022559	Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence	33980-34015	3	0.917
NC_014915_8	8.4\|2962699\|38\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	2962699-2962736	38	NZ_CP017691	Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence	46716-46753	3	0.921
NC_014915_8	8.13\|2963297\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	2963297-2963331	35	MK560763	Virgibacillus phage Mimir87, complete genome	33954-33988	3	0.914
NC_014915_8	8.22\|2963892\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	2963892-2963926	35	NZ_AP022558	Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence	53208-53242	3	0.914
NC_014915_8	8.22\|2963892\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	2963892-2963926	35	NZ_AP022558	Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence	53658-53692	3	0.914
NC_014915_6	6.28\|1990936\|36\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1990936-1990971	36	AB823818	Phage phi OH2 DNA, complete genome	18225-18260	4	0.889
NC_014915_3	3.26\|365190\|39\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365190-365228	39	NZ_AP022558	Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence	51610-51648	6	0.846
NC_014915_3	3.20\|364790\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	364790-364824	35	NC_023599	Bacillus phage phiCM3, complete genome	27156-27190	7	0.8
NC_014915_3	3.35\|365785\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365785-365819	35	MF417982	Uncultured Caudovirales phage clone 7F_2, partial genome	397-431	7	0.8
NC_014915_3	3.35\|365785\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365785-365819	35	NZ_CP046399	Bacillus sp. A260 plasmid unnamed11, complete sequence	84352-84386	7	0.8
NC_014915_3	3.15\|364460\|36\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	364460-364495	36	NZ_CP012104	Bacillus thuringiensis strain HS18-1 plasmid pHS18-5, complete sequence	18914-18949	8	0.778
NC_014915_3	3.35\|365785\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365785-365819	35	NC_042127	Enterococcus phage vB_EfaS_AL2, complete genome	1550-1584	8	0.771
NC_014915_3	3.35\|365785\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365785-365819	35	KF733017	Enterococcus phage IME-EF4, complete genome	1563-1597	8	0.771
NC_014915_7	7.14\|2961086\|35\|NC_014915\|CRISPRCasFinder,CRT	2961086-2961120	35	NZ_CP051728	Escherichia coli strain SCU-111 plasmid pSCU-111-1, complete sequence	104483-104517	8	0.771
NC_014915_7	7.32\|2961087\|35\|NC_014915\|PILER-CR	2961087-2961121	35	NZ_CP051728	Escherichia coli strain SCU-111 plasmid pSCU-111-1, complete sequence	104483-104517	8	0.771
NC_014915_1	1.22\|340804\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	340804-340838	35	GU580940	Rhodococcus phage ReqiDocB7, complete genome	57242-57276	9	0.743
NC_014915_3	3.9\|364058\|37\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	364058-364094	37	MN693886	Marine virus AFVG_250M878, complete genome	6303-6339	9	0.757
NC_014915_3	3.35\|365785\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365785-365819	35	MF417885	Uncultured Caudovirales phage clone 3S_9, partial genome	27712-27746	9	0.743
NC_014915_3	3.35\|365785\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365785-365819	35	NZ_CP022320	Bacillus altitudinis strain SGAir0031 plasmid pSGAir0031, complete sequence	15941-15975	9	0.743
NC_014915_6	6.8\|1989610\|35\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1989610-1989644	35	NZ_CP048281	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence	695221-695255	9	0.743
NC_014915_6	6.8\|1989610\|35\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1989610-1989644	35	NZ_CP013426	Burkholderia sp. MSMB0856 plasmid pMSMB0856, complete sequence	9656-9690	9	0.743
NC_014915_6	6.8\|1989610\|35\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1989610-1989644	35	NZ_CP028965	Burkholderia sp. IDO3 plasmid p1, complete sequence	406193-406227	9	0.743
NC_014915_6	6.33\|1991267\|35\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1991267-1991301	35	NZ_CP030100	Roseovarius sp. AK1035 plasmid unnamed, complete sequence	64309-64343	9	0.743
NC_014915_6	6.33\|1991267\|35\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1991267-1991301	35	NZ_CP020475	Roseovarius mucosus strain SMR3 plasmid pSMR3-1, complete sequence	32349-32383	9	0.743
NC_014915_7	7.14\|2961086\|35\|NC_014915\|CRISPRCasFinder,CRT	2961086-2961120	35	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1017837-1017871	9	0.743
NC_014915_7	7.14\|2961086\|35\|NC_014915\|CRISPRCasFinder,CRT	2961086-2961120	35	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1378140-1378174	9	0.743
NC_014915_7	7.14\|2961086\|35\|NC_014915\|CRISPRCasFinder,CRT	2961086-2961120	35	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	200993-201027	9	0.743
NC_014915_7	7.32\|2961087\|35\|NC_014915\|PILER-CR	2961087-2961121	35	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1017837-1017871	9	0.743
NC_014915_7	7.32\|2961087\|35\|NC_014915\|PILER-CR	2961087-2961121	35	NZ_CP032322	Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence	1378140-1378174	9	0.743
NC_014915_7	7.32\|2961087\|35\|NC_014915\|PILER-CR	2961087-2961121	35	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	200993-201027	9	0.743
NC_014915_3	3.35\|365785\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365785-365819	35	NZ_CP053952	Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence	411922-411956	10	0.714
NC_014915_3	3.35\|365785\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365785-365819	35	NZ_CP053949	Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence	61980-62014	10	0.714
NC_014915_6	6.25\|1990736\|35\|NC_014915\|CRISPRCasFinder,CRT,PILER-CR	1990736-1990770	35	MH341451	Listeria phage PSU-VKH-LP019, complete genome	21470-21504	10	0.714
NC_014915_3	3.35\|365785\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	365785-365819	35	KT588072	Enterococcus phage IME-EFm5, complete genome	15459-15493	11	0.686
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP028554	Klebsiella variicola strain WCHKP19 plasmid pKPC2_020019, complete sequence	69841-69874	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_KY399973	Enterobacter cloacae strain EClY2403 plasmid pKPC2_EClY2403, complete sequence	84844-84877	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_KY399972	Enterobacter cloacae strain EClY2402 plasmid pKPC2_EClY2402, complete sequence	84844-84877	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_KP868646	Enterobacter cloacae strain WCHECl-14653 plasmid pKPC2-EC14653, complete sequence	84845-84878	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP048352	Raoultella ornithinolytica strain 23 plasmid p23_C, complete sequence	137561-137594	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP023418	Klebsiella pneumoniae strain 1050 plasmid pKp1050-2, complete sequence	132059-132092	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP029448	Serratia marcescens strain CAV1761 plasmid pCAV1761-205, complete sequence	31701-31734	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	MN891677	Klebsiella pneumoniae strain ZZ41 plasmid pZZ41-KPC, complete sequence	7781-7814	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP022349	Klebsiella michiganensis strain K516 plasmid pK516_KPC, complete sequence	125084-125117	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP041249	Raoultella electrica strain DSM 102253 plasmid unnamed2, complete sequence	66112-66145	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP024509	Klebsiella pneumoniae strain KSB2_1B plasmid unnamed3, complete sequence	133878-133911	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_AP014954	Klebsiella oxytoca strain JKo3 plasmid pKO_JKo3_3, complete sequence	74655-74688	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_MH192342	Klebsiella grimontii strain WCHKG020121 plasmid pKPC2_020121, complete sequence	86128-86161	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	MN661403	Klebsiella quasipneumoniae strain KP18-31 plasmid pKP18-31-2, complete sequence	112984-113017	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP044528	Klebsiella grimontii strain SS141 plasmid plamid_1, complete sequence	125996-126029	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP020359	Klebsiella oxytoca strain AR_0147 plasmid unitig_2, complete sequence	79100-79133	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP021328	Raoultella ornithinolytica strain Ro24724 plasmid pRo24724, complete sequence	91490-91523	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP008789	Klebsiella oxytoca KONIH1 plasmid pKOX-137, complete sequence	64919-64952	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP022275	Citrobacter freundii strain 18-1 plasmid pBKPC18-1, complete sequence	106015-106048	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	MN891679	Klebsiella pneumoniae strain ZZ40 plasmid pZZ40-KPC, complete sequence	75899-75932	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	MN310380	Raoultella ornithinolytica strain 170602815 plasmid p602815-NR, complete sequence	123870-123903	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP026272	Klebsiella oxytoca strain KONIH4 plasmid pKPC-f607, complete sequence	54521-54554	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP038275	Raoultella ornithinolytica strain WLK218 plasmid pWLK-101716, complete sequence	49999-50032	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP038276	Raoultella ornithinolytica strain WLK218 plasmid pWLK-107717, complete sequence	77309-77342	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP011641	Serratia marcescens strain CAV1492 plasmid pCAV1492-199, complete sequence	78409-78442	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP023186	Klebsiella michiganensis strain K518 plasmid pK518_KPC, complete sequence	67319-67352	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	NZ_CP018361	Klebsiella oxytoca strain CAV1752 plasmid pCAV1752-278, complete sequence	200385-200418	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	MN661402	Klebsiella quasipneumoniae strain KP18-31 plasmid pKP18-31-IMP,KPC, complete sequence	27833-27866	11	0.676
NC_014915_5	5.1\|1981042\|34\|NC_014915\|CRISPRCasFinder	1981042-1981075	34	MT108213	Klebsiella pneumoniae strain ZZ100 plasmid pZZ100-KPC, complete sequence	73577-73610	11	0.676

1. spacer 1.5|339674|37|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_008376 (Geobacillus phage GBSV1, complete genome) position: , mismatch: 0, identity: 1.0

ttccacctctaacagctcggccgggatgatccaaggc	CRISPR spacer
ttccacctctaacagctcggccgggatgatccaaggc	Protospacer
*************************************

2. spacer 1.10|340007|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_009552 (Geobacillus virus E2, complete genome) position: , mismatch: 0, identity: 1.0

atggaacgatcacggtacataatgatgatcgtcgc	CRISPR spacer
atggaacgatcacggtacataatgatgatcgtcgc	Protospacer
***********************************

3. spacer 1.22|340804|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022559 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence) position: , mismatch: 0, identity: 1.0

caagaggcgatcgaggacaaggctgagaatatcgg	CRISPR spacer
caagaggcgatcgaggacaaggctgagaatatcgg	Protospacer
***********************************

4. spacer 2.23|351214|36|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_008376 (Geobacillus phage GBSV1, complete genome) position: , mismatch: 0, identity: 1.0

aggtgaccattgataaaaaagaaacagaaaaacttc	CRISPR spacer
aggtgaccattgataaaaaagaaacagaaaaacttc	Protospacer
************************************

5. spacer 2.30|351680|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 0, identity: 1.0

ttcagaatgagtcctgtcacggtatacccattttt	CRISPR spacer
ttcagaatgagtcctgtcacggtatacccattttt	Protospacer
***********************************

6. spacer 3.1|363522|38|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_009552 (Geobacillus virus E2, complete genome) position: , mismatch: 0, identity: 1.0

ccaagtaccaaaagtggcttttggatttcaacacgatc	CRISPR spacer
ccaagtaccaaaagtggcttttggatttcaacacgatc	Protospacer
**************************************

7. spacer 3.7|363922|38|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 0, identity: 1.0

atatgccagtttgattttgttaaacaccgtttcaatgc	CRISPR spacer
atatgccagtttgattttgttaaacaccgtttcaatgc	Protospacer
**************************************

8. spacer 3.15|364460|36|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 0, identity: 1.0

ttctcaagcgcaatcaatttccatttgcggctttcc	CRISPR spacer
ttctcaagcgcaatcaatttccatttgcggctttcc	Protospacer
************************************

9. spacer 3.20|364790|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022559 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence) position: , mismatch: 0, identity: 1.0

aaggaggtgatagaagtgacaaaagaagagattgt	CRISPR spacer
aaggaggtgatagaagtgacaaaagaagagattgt	Protospacer
***********************************

10. spacer 6.31|1991131|38|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 0, identity: 1.0

cgtgcaccaatccttgtgtgatctcctgttggatggta	CRISPR spacer
cgtgcaccaatccttgtgtgatctcctgttggatggta	Protospacer
**************************************

11. spacer 8.8|2962967|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 0, identity: 1.0

aaccgcggcagtgtatcgcttccattcgtcgtccg	CRISPR spacer
aaccgcggcagtgtatcgcttccattcgtcgtccg	Protospacer
***********************************

12. spacer 8.8|2962967|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_009552 (Geobacillus virus E2, complete genome) position: , mismatch: 0, identity: 1.0

aaccgcggcagtgtatcgcttccattcgtcgtccg	CRISPR spacer
aaccgcggcagtgtatcgcttccattcgtcgtccg	Protospacer
***********************************

13. spacer 8.9|2963032|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 0, identity: 1.0

ggccgtgccgctggctttttggtgctgaagtcgaa	CRISPR spacer
ggccgtgccgctggctttttggtgctgaagtcgaa	Protospacer
***********************************

14. spacer 1.10|340007|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 1, identity: 0.971

atggaacgatcacggtacataatgatgatcgtcgc	CRISPR spacer
atggaacgatcacgatacataatgatgatcgtcgc	Protospacer
**************.********************

15. spacer 1.20|340669|38|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022559 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence) position: , mismatch: 1, identity: 0.974

tttttgaaggtcgcgaatgtttctcggaggggcataac	CRISPR spacer
tttttgaaggtcgcgaatgtttctcgaaggggcataac	Protospacer
**************************.***********

16. spacer 2.36|352076|34|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 1, identity: 0.971

ctccgcaaacgaccacgccatcgggtggccagcg	CRISPR spacer
ctccgcgaacgaccacgccatcgggtggccagcg	Protospacer
******.***************************

17. spacer 3.6|363854|38|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 1, identity: 0.974

tggtactgcgcgcgaatccgctggcattagccattacc	CRISPR spacer
tggtactgcgcgcgaatccgctggcattagccgttacc	Protospacer
********************************.*****

18. spacer 3.20|364790|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_009552 (Geobacillus virus E2, complete genome) position: , mismatch: 1, identity: 0.971

aaggaggtgatagaagtgacaaaagaagagattgt	CRISPR spacer
aaggaggtgatagaagtgacaaaggaagagattgt	Protospacer
***********************.***********

19. spacer 6.28|1990936|36|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015439 (Anoxybacillus amylolyticus strain DSM 15939 plasmid pDSM15939_1, complete sequence) position: , mismatch: 1, identity: 0.972

ttaacggcatgcgctcccacagatacggcttctcgt	CRISPR spacer
tcaacggcatgcgctcccacagatacggcttctcgt	Protospacer
*.**********************************

20. spacer 6.30|1991067|34|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 1, identity: 0.971

gaatccggtgtatagcatgatgatgctatttgga	CRISPR spacer
taatccggtgtatagcatgatgatgctatttgga	Protospacer
 *********************************

21. spacer 1.24|340934|37|NC_014915|CRISPRCasFinder,CRT matches to NZ_AP022559 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence) position: , mismatch: 2, identity: 0.946

tctgaccgctgctccactgatcggtttaattgagcca	CRISPR spacer
tctgaccgctgctctactgatcggttcaattgagcca	Protospacer
**************.***********.**********

22. spacer 2.4|349933|37|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 2, identity: 0.946

ccaatctatttccaacggtggaatagcatcggtattc	CRISPR spacer
ccaatctatttccgacggtggaatagcatcggcattc	Protospacer
*************.******************.****

23. spacer 2.8|350203|38|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022558 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence) position: , mismatch: 2, identity: 0.947

cccgacatgttccgaaactttaactctggggcgttgac	CRISPR spacer
cccgacatgtttcgaaactttagctctggggcgttgac	Protospacer
***********.**********.***************

24. spacer 3.17|364592|36|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_019544 (Deep-sea thermophilic phage D6E, complete genome) position: , mismatch: 2, identity: 0.944

aaagacgaccgtttcgtcaaaacaggcagcctcccg	CRISPR spacer
aaagacgaccgtttcgtcaaaacaggcagcctttcg	Protospacer
********************************..**

25. spacer 3.22|364924|37|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022558 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence) position: , mismatch: 2, identity: 0.946

ttcaaccccccgatgtcggtgatcgccaccgttttgt	CRISPR spacer
ttcaaccctccgatgtcggtgatcgccacggttttgt	Protospacer
********.******************** *******

26. spacer 3.25|365124|36|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022559 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence) position: , mismatch: 2, identity: 0.944

aactccttcgccatttctttcagcgatcgggacaat	CRISPR spacer
aactccttcgccatttctttcagcgatcttgacaat	Protospacer
****************************  ******

27. spacer 6.20|1990406|35|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NC_009552 (Geobacillus virus E2, complete genome) position: , mismatch: 2, identity: 0.943

gcaagagccatcgctgacgctgtttctaaaacgat	CRISPR spacer
gcaaaagccatcgctgacgctgtttctaaaacaat	Protospacer
****.***************************.**

28. spacer 6.34|1991332|37|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022558 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence) position: , mismatch: 2, identity: 0.946

cgaagccaaagcggttgacagcgagggcaacgaaagc	CRISPR spacer
cgaggccaaagcggttgacagcgagggaaacgaaagc	Protospacer
***.*********************** *********

29. spacer 7.2|2960284|36|NC_014915|CRISPRCasFinder,CRT matches to NZ_AP022558 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence) position: , mismatch: 2, identity: 0.944

tttgtggtgtcgttcgttttcgcagtaatgaagaaa	CRISPR spacer
tttgtggcctcgttcgttttcgcagtaatgaagaaa	Protospacer
*******. ***************************

30. spacer 7.20|2960285|36|NC_014915|PILER-CR matches to NZ_AP022558 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence) position: , mismatch: 2, identity: 0.944

tttgtggtgtcgttcgttttcgcagtaatgaagaaa	CRISPR spacer
tttgtggcctcgttcgttttcgcagtaatgaagaaa	Protospacer
*******. ***************************

31. spacer 8.22|2963892|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022558 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence) position: , mismatch: 2, identity: 0.943

taccgaaccacgcctgttcaagtgcaagggctgtc	CRISPR spacer
tatcaaaccacgcctgttcaagtgcaagggctgtc	Protospacer
**.*.******************************

32. spacer 8.22|2963892|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022558 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence) position: , mismatch: 2, identity: 0.943

taccgaaccacgcctgttcaagtgcaagggctgtc	CRISPR spacer
tatcaaaccacgcctgttcaagtgcaagggctgtc	Protospacer
**.*.******************************

33. spacer 6.6|1989478|36|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022559 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-2, complete sequence) position: , mismatch: 3, identity: 0.917

aagaaatgcaacggcatggtattgatgtctctattg	CRISPR spacer
aggaaatgcagcggaatggtattgatgtctctattg	Protospacer
*.********.*** *********************

34. spacer 8.4|2962699|38|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017691 (Geobacillus thermodenitrificans strain ID-1 plasmid pLDW-2, complete sequence) position: , mismatch: 3, identity: 0.921

tgaattcgttttaactcgagatttaggtcggttatttt	CRISPR spacer
cgaattcgttttaactcgagattcaggtctgttatttt	Protospacer
.**********************.***** ********

35. spacer 8.13|2963297|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to MK560763 (Virgibacillus phage Mimir87, complete genome) position: , mismatch: 3, identity: 0.914

tggtatcgtaaacttcagtggctgatttgaatttg	CRISPR spacer
tggtgtcgtatacttcagtggctgatttgaattta	Protospacer
****.***** ***********************.

36. spacer 8.22|2963892|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022558 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence) position: , mismatch: 3, identity: 0.914

taccgaaccacgcctgttcaagtgcaagggctgtc	CRISPR spacer
agccgaactacgcctgttcaagtgcaagggctgtc	Protospacer
 .******.**************************

37. spacer 8.22|2963892|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022558 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence) position: , mismatch: 3, identity: 0.914

taccgaaccacgcctgttcaagtgcaagggctgtc	CRISPR spacer
aaccaaaccaggcctgttcaagtgcaagggctgtc	Protospacer
 ***.***** ************************

38. spacer 6.28|1990936|36|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to AB823818 (Phage phi OH2 DNA, complete genome) position: , mismatch: 4, identity: 0.889

ttaacggcatgcgctcccacagatacggcttctcgt	CRISPR spacer
tcaacggcatgcgctcccacagatacggctttccat	Protospacer
*.*****************************..*.*

39. spacer 3.26|365190|39|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022558 (Geobacillus subterraneus strain E55-1 plasmid pGspE55-1, complete sequence) position: , mismatch: 6, identity: 0.846

acaagcatgcgtatcaaaaggtggcggcggttccgttgg	CRISPR spacer
taacgtatgcgtatcaaaaggtggcggcggtgccattgg	Protospacer
  * *.************************* **.****

40. spacer 3.20|364790|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_023599 (Bacillus phage phiCM3, complete genome) position: , mismatch: 7, identity: 0.8

aaggaggtgatagaagtgacaaaagaagagattgt	CRISPR spacer
atagggggaatagaaatgacgaaagaagagattgt	Protospacer
* .*.** .******.****.**************

41. spacer 3.35|365785|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to MF417982 (Uncultured Caudovirales phage clone 7F_2, partial genome) position: , mismatch: 7, identity: 0.8

ttccaatttttttcattctacattcctccttagtt	CRISPR spacer
ataaaacctttttcattctacatttctcctttgtt	Protospacer
 *  **..****************.****** ***

42. spacer 3.35|365785|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046399 (Bacillus sp. A260 plasmid unnamed11, complete sequence) position: , mismatch: 7, identity: 0.8

ttccaatttt-----tttcattctacattcctccttagtt	CRISPR spacer
-----attttcgcgctttcattctatattcctccttcgtt	Protospacer
     *****     **********.********** ***

43. spacer 3.15|364460|36|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012104 (Bacillus thuringiensis strain HS18-1 plasmid pHS18-5, complete sequence) position: , mismatch: 8, identity: 0.778

ttctcaagcgcaatcaatttccatttgcggctttcc	CRISPR spacer
aactcaagagcaatcaacttccatttgcgagcttca	Protospacer
  ****** ********.***********. .***

44. spacer 3.35|365785|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_042127 (Enterococcus phage vB_EfaS_AL2, complete genome) position: , mismatch: 8, identity: 0.771

ttccaatttttttcattctacattcctccttagtt	CRISPR spacer
cttctttgtgttgcattttacattcctccttagtt	Protospacer
.*.*  * * ** ****.*****************

45. spacer 3.35|365785|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to KF733017 (Enterococcus phage IME-EF4, complete genome) position: , mismatch: 8, identity: 0.771

ttccaatttttttcattctacattcctccttagtt	CRISPR spacer
cttctttgtgttgcattttacattcctccttagtt	Protospacer
.*.*  * * ** ****.*****************

46. spacer 7.14|2961086|35|NC_014915|CRISPRCasFinder,CRT matches to NZ_CP051728 (Escherichia coli strain SCU-111 plasmid pSCU-111-1, complete sequence) position: , mismatch: 8, identity: 0.771

gccagccggaacagccacaacagcaggatttgcct	CRISPR spacer
aacagccgcaacagccacaacagccggtgtctcct	Protospacer
. ****** *************** **  *. ***

47. spacer 7.32|2961087|35|NC_014915|PILER-CR matches to NZ_CP051728 (Escherichia coli strain SCU-111 plasmid pSCU-111-1, complete sequence) position: , mismatch: 8, identity: 0.771

gccagccggaacagccacaacagcaggatttgcct	CRISPR spacer
aacagccgcaacagccacaacagccggtgtctcct	Protospacer
. ****** *************** **  *. ***

48. spacer 1.22|340804|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to GU580940 (Rhodococcus phage ReqiDocB7, complete genome) position: , mismatch: 9, identity: 0.743

caagaggcgatcgaggacaaggctgagaatatcgg	CRISPR spacer
gacatgcagatcgaggacaaggctaagaagatcga	Protospacer
 * . *  ****************.**** ****.

49. spacer 3.9|364058|37|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to MN693886 (Marine virus AFVG_250M878, complete genome) position: , mismatch: 9, identity: 0.757

atttttctaattactttagtatcatttactatttttt	CRISPR spacer
aaaattttaattactttattatcatttactatgacat	Protospacer
*   **.*********** *************  . *

50. spacer 3.35|365785|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to MF417885 (Uncultured Caudovirales phage clone 3S_9, partial genome) position: , mismatch: 9, identity: 0.743

ttccaatttttttcattctacattcctccttagtt	CRISPR spacer
aattaattattttcattctacatttctcctttata	Protospacer
  ..**** ***************.****** .*

51. spacer 3.35|365785|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022320 (Bacillus altitudinis strain SGAir0031 plasmid pSGAir0031, complete sequence) position: , mismatch: 9, identity: 0.743

ttccaatttttttcattctacattcctccttagtt	CRISPR spacer
tgcgtagttttttcattctacactccttcttacgg	Protospacer
* *  * ***************.****.****

52. spacer 6.8|1989610|35|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP048281 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence) position: , mismatch: 9, identity: 0.743

attttgcctggtcgtagcggcgggcgtcaatgttg	CRISPR spacer
tcagtgcctggtcgtagcggcgcgcggcaagatcg	Protospacer
 .  ****************** *** *** .*.*

53. spacer 6.8|1989610|35|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013426 (Burkholderia sp. MSMB0856 plasmid pMSMB0856, complete sequence) position: , mismatch: 9, identity: 0.743

attttgcctggtcgtagcggcgggcgtcaatgttg	CRISPR spacer
gctttccctggtcgaagcggcgggcgtgatggccg	Protospacer
..*** ******** ************ *  *..*

54. spacer 6.8|1989610|35|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP028965 (Burkholderia sp. IDO3 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.743

attttgcctggtcgtagcggcgggcgtcaatgttg	CRISPR spacer
gctttccctggtcgaagcggcgggcgtgatggccg	Protospacer
..*** ******** ************ *  *..*

55. spacer 6.33|1991267|35|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030100 (Roseovarius sp. AK1035 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.743

gcgaag----catcgcgcctgaaattaacgatgtgctta	CRISPR spacer
----agtccctgtcgcgcctgaagtgaacgatgtgctga	Protospacer
    **    ..***********.* *********** *

56. spacer 6.33|1991267|35|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020475 (Roseovarius mucosus strain SMR3 plasmid pSMR3-1, complete sequence) position: , mismatch: 9, identity: 0.743

gcgaag----catcgcgcctgaaattaacgatgtgctta	CRISPR spacer
----agtccctgtcgcgcctgaagtgaacgatgtgctga	Protospacer
    **    ..***********.* *********** *

57. spacer 7.14|2961086|35|NC_014915|CRISPRCasFinder,CRT matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 9, identity: 0.743

gccagccggaacagccacaacagcaggatttgcct	CRISPR spacer
tccagccggaacagccggaacagcagccgttccgc	Protospacer
 ***************. ********   ** * .

58. spacer 7.14|2961086|35|NC_014915|CRISPRCasFinder,CRT matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.743

gccagccggaacagccacaacagcaggatttgcct	CRISPR spacer
tccagccggaacagccggaacagcagccgttccgc	Protospacer
 ***************. ********   ** * .

59. spacer 7.14|2961086|35|NC_014915|CRISPRCasFinder,CRT matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 9, identity: 0.743

gccagccggaacagccacaacagcaggatttgcct	CRISPR spacer
tccagccggaacagccggaacagcagccgttccgc	Protospacer
 ***************. ********   ** * .

60. spacer 7.32|2961087|35|NC_014915|PILER-CR matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 9, identity: 0.743

gccagccggaacagccacaacagcaggatttgcct	CRISPR spacer
tccagccggaacagccggaacagcagccgttccgc	Protospacer
 ***************. ********   ** * .

61. spacer 7.32|2961087|35|NC_014915|PILER-CR matches to NZ_CP032322 (Azospirillum brasilense strain MTCC4035 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.743

gccagccggaacagccacaacagcaggatttgcct	CRISPR spacer
tccagccggaacagccggaacagcagccgttccgc	Protospacer
 ***************. ********   ** * .

62. spacer 7.32|2961087|35|NC_014915|PILER-CR matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 9, identity: 0.743

gccagccggaacagccacaacagcaggatttgcct	CRISPR spacer
tccagccggaacagccggaacagcagccgttccgc	Protospacer
 ***************. ********   ** * .

63. spacer 3.35|365785|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053952 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

ttccaatttttttcattctacattcctccttagtt	CRISPR spacer
acaatatttttttcattataaattcctcctaacct	Protospacer
 .   ************ ** ********* * .*

64. spacer 3.35|365785|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053949 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.714

ttccaatttttttcattctacattcctccttagtt	CRISPR spacer
acaatatttttttcattataaattcctcctaacct	Protospacer
 .   ************ ** ********* * .*

65. spacer 6.25|1990736|35|NC_014915|CRISPRCasFinder,CRT,PILER-CR matches to MH341451 (Listeria phage PSU-VKH-LP019, complete genome) position: , mismatch: 10, identity: 0.714

tttttgctgtgtttggtgtatttgatgagttgctc	CRISPR spacer
tttttgctttgtttggtggatttgacacattatca	Protospacer
******** ********* ******.. .**...

66. spacer 3.35|365785|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to KT588072 (Enterococcus phage IME-EFm5, complete genome) position: , mismatch: 11, identity: 0.686

ttccaatttttttcattctacattcctccttagtt	CRISPR spacer
agtttatttttttcattctacatcactcctatttc	Protospacer
  .. ******************. *****   *.

67. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP028554 (Klebsiella variicola strain WCHKP19 plasmid pKPC2_020019, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

68. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_KY399973 (Enterobacter cloacae strain EClY2403 plasmid pKPC2_EClY2403, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

69. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_KY399972 (Enterobacter cloacae strain EClY2402 plasmid pKPC2_EClY2402, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

70. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_KP868646 (Enterobacter cloacae strain WCHECl-14653 plasmid pKPC2-EC14653, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

71. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP048352 (Raoultella ornithinolytica strain 23 plasmid p23_C, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

72. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP023418 (Klebsiella pneumoniae strain 1050 plasmid pKp1050-2, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

73. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP029448 (Serratia marcescens strain CAV1761 plasmid pCAV1761-205, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

74. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to MN891677 (Klebsiella pneumoniae strain ZZ41 plasmid pZZ41-KPC, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

75. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP022349 (Klebsiella michiganensis strain K516 plasmid pK516_KPC, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

76. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP041249 (Raoultella electrica strain DSM 102253 plasmid unnamed2, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

77. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP024509 (Klebsiella pneumoniae strain KSB2_1B plasmid unnamed3, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

78. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_AP014954 (Klebsiella oxytoca strain JKo3 plasmid pKO_JKo3_3, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

79. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_MH192342 (Klebsiella grimontii strain WCHKG020121 plasmid pKPC2_020121, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

80. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to MN661403 (Klebsiella quasipneumoniae strain KP18-31 plasmid pKP18-31-2, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

81. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP044528 (Klebsiella grimontii strain SS141 plasmid plamid_1, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

82. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP020359 (Klebsiella oxytoca strain AR_0147 plasmid unitig_2, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

83. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP021328 (Raoultella ornithinolytica strain Ro24724 plasmid pRo24724, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

84. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP008789 (Klebsiella oxytoca KONIH1 plasmid pKOX-137, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

85. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP022275 (Citrobacter freundii strain 18-1 plasmid pBKPC18-1, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

86. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to MN891679 (Klebsiella pneumoniae strain ZZ40 plasmid pZZ40-KPC, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

87. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to MN310380 (Raoultella ornithinolytica strain 170602815 plasmid p602815-NR, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

88. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP026272 (Klebsiella oxytoca strain KONIH4 plasmid pKPC-f607, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

89. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP038275 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-101716, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

90. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP038276 (Raoultella ornithinolytica strain WLK218 plasmid pWLK-107717, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

91. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP011641 (Serratia marcescens strain CAV1492 plasmid pCAV1492-199, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

92. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP023186 (Klebsiella michiganensis strain K518 plasmid pK518_KPC, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

93. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to NZ_CP018361 (Klebsiella oxytoca strain CAV1752 plasmid pCAV1752-278, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

94. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to MN661402 (Klebsiella quasipneumoniae strain KP18-31 plasmid pKP18-31-IMP,KPC, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

95. spacer 5.1|1981042|34|NC_014915|CRISPRCasFinder matches to MT108213 (Klebsiella pneumoniae strain ZZ100 plasmid pZZ100-KPC, complete sequence) position: , mismatch: 11, identity: 0.676

tggcccggcttgtcggagatgaccgttgtaaacg	CRISPR spacer
tggtccggcttgccggagatgaccgcccctggaa	Protospacer
***.********.************.. . .. .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

212313 : 264155

uncultured_virus(28.57%)

transposase,protease,coat,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013522789.1\|212313_212820_+\|coat	spore coat protein	NA	NA	NA	NA
WP_013522790.1\|213068_214007_+	ROK family protein	NA	NA	NA	NA
WP_013144033.1\|214190_215012_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_013522791.1\|218495_219098_+	hypothetical protein	NA	NA	NA	NA
WP_013522792.1\|219278_220112_+	hypothetical protein	NA	NA	NA	NA
WP_013522793.1\|220358_222017_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_013522794.1\|223515_224589_-	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_013144037.1\|224967_225696_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_013522795.1\|225706_226303_+	DedA family protein	NA	NA	NA	NA
WP_013144038.1\|226315_227458_+	galactosyldiacylglycerol synthase	NA	NA	NA	NA
WP_013522796.1\|227711_228815_+	D-alanine--D-alanine ligase	NA	NA	NA	NA
WP_013522797.1\|228821_230198_+	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase	NA	NA	NA	NA
WP_013522798.1\|230270_230993_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_013144041.1\|231053_232457_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.7e-64	36.9
WP_013522799.1\|232468_233086_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_011229738.1\|233199_233589_+	holo-ACP synthase	NA	NA	NA	NA
WP_013522800.1\|233668_234682_+	outer membrane lipoprotein carrier protein LolA	NA	NA	NA	NA
WP_013522801.1\|234930_236085_+	alanine racemase	NA	NA	NA	NA
WP_013144044.1\|236211_236493_+	hypothetical protein	NA	NA	NA	NA
WP_003253417.1\|236497_236848_+	type II toxin-antitoxin system endoribonuclease NdoA	A0A2P0ZKX3	Lactobacillus_phage	2.0e-14	38.6
WP_013522802.1\|237113_239279_+	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_013144046.1\|239297_239411_-	cortex morphogenetic protein CmpA	NA	NA	NA	NA
WP_013144047.1\|239500_239950_+	SprT family protein	U5J9G1	Bacillus_phage	4.9e-05	26.6
WP_156779977.1\|247909_248164_+	hypothetical protein	NA	NA	NA	NA
WP_013144048.1\|248150_248609_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_011229746.1\|248605_249346_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_011229747.1\|249305_249758_+	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_013144049.1\|249754_250768_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	2.3e-66	43.6
WP_013144050.1\|251101_253027_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	2.6e-63	34.3
WP_011229750.1\|253123_253612_+	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_013144051.1\|253627_254269_+	redox-sensing transcriptional repressor Rex	NA	NA	NA	NA
WP_013144052.1\|254286_254439_+	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_013144053.1\|254459_255203_+	twin-arginine translocase subunit TatC	NA	NA	NA	NA
WP_013522803.1\|255386_255566_-	YdiK family protein	NA	NA	NA	NA
WP_013522804.1\|255562_256297_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_013144057.1\|256652_256937_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	1.1e-18	50.5
WP_013144058.1\|257041_258658_+	chaperonin GroEL	A0A219YK78	uncultured_virus	5.8e-165	59.1
WP_013522805.1\|259176_260457_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_013522806.1\|262496_264155_+\|transposase	IS1634 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

282240 : 290658

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013144127.1\|282240_283536_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	3.8e-18	33.6
WP_013522817.1\|283611_284340_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3HI61	Synechococcus_phage	7.1e-46	42.9
WP_013522818.1\|284327_284582_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_013522819.1\|284578_285265_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_013144130.1\|285248_287477_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.6e-168	42.2
WP_013522820.1\|287452_288865_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	8.3e-51	34.7
WP_013522821.1\|288988_290029_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FC27	Synechococcus_phage	3.2e-68	44.5
WP_013522822.1\|290025_290658_+	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	2.4e-26	37.9

DBSCAN-SWA_3

937359 : 943831

Pneumococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173346446.1\|937359_938025_+	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	1.2e-68	58.4
WP_011230477.1\|938021_938459_+	6-carboxytetrahydropterin synthase QueD	A0A1U9WRB3	Streptococcus_virus	9.6e-06	33.0
WP_013523275.1\|938458_939193_+	7-carboxy-7-deazaguanine synthase QueE	E7DN68	Pneumococcus_phage	1.3e-55	44.6
WP_013523276.1\|939245_939743_+	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.7e-51	67.2
WP_013523277.1\|939796_940480_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_013523278.1\|940511_940691_-	DUF2187 family protein	NA	NA	NA	NA
WP_013145941.1\|940992_941577_-	cell wall hydrolase	A0A172JHR8	Bacillus_phage	5.0e-42	46.8
WP_011230483.1\|941777_941972_-	hypothetical protein	NA	NA	NA	NA
WP_013523279.1\|942143_942812_+	hypothetical protein	NA	NA	NA	NA
WP_013523280.1\|943081_943831_+	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	5.4e-17	31.2

DBSCAN-SWA_4

1187368 : 1259881

Clostridium_phage(12.5%)

transposase,coat,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_173346434.1\|1187368_1188634_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_013523414.1\|1188657_1190361_+\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_013523415.1\|1190433_1194768_+	PolC-type DNA polymerase III	A0A0A7RWA3	Clostridium_phage	4.4e-26	41.2
WP_013523416.1\|1195012_1195486_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_013145730.1\|1195510_1196662_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_011230761.1\|1196675_1196966_+	YlxR family protein	NA	NA	NA	NA
WP_011230762.1\|1196955_1197264_+	YlxQ family RNA-binding protein	NA	NA	NA	NA
WP_013523417.1\|1197277_1199497_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	3.5e-19	24.6
WP_011230764.1\|1199493_1199772_+	DUF503 family protein	NA	NA	NA	NA
WP_013145728.1\|1199787_1200171_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_013523418.1\|1200225_1201134_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_041469415.1\|1201177_1202158_+	bifunctional riboflavin kinase/FAD synthetase	A0A1V0SD03	Indivirus	3.0e-07	27.8
WP_011230768.1\|1202245_1202515_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_013523420.1\|1202655_1204827_+	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_012820510.1\|1205008_1206289_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_013145724.1\|1206686_1207670_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_013145723.1\|1207656_1208904_+	insulinase family protein	G3MBJ8	Bacillus_virus	2.4e-54	33.3
WP_011230772.1\|1208966_1209209_-	YlmC/YmxH family sporulation protein	NA	NA	NA	NA
WP_013145722.1\|1209401_1210307_+	dipicolinic acid synthetase subunit A	NA	NA	NA	NA
WP_013145721.1\|1210303_1210909_+	dipicolinate synthase subunit B	NA	NA	NA	NA
WP_013145720.1\|1211020_1212064_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_013523421.1\|1212084_1213338_+	aspartate kinase	NA	NA	NA	NA
WP_013523422.1\|1213343_1214219_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_013523423.1\|1214386_1216057_+	ribonuclease J	NA	NA	NA	NA
WP_013523424.1\|1216174_1216915_+\|protease	ClpP family protease	NA	NA	NA	NA
WP_013145716.1\|1216911_1217136_+	YlzJ-like family protein	NA	NA	NA	NA
WP_013523425.1\|1217244_1219575_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.6e-86	50.0
WP_013145714.1\|1219784_1220516_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_013523426.1\|1220603_1221695_+	BMP family protein	A0A0A7DN02	Lactobacillus_phage	2.4e-58	35.2
WP_013523427.1\|1221822_1223349_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	2.2e-12	26.5
WP_013145711.1\|1223348_1224395_+	ABC transporter permease	NA	NA	NA	NA
WP_011230786.1\|1224395_1225355_+	ABC transporter permease	NA	NA	NA	NA
WP_013145710.1\|1225508_1226804_+	insulinase family protein	A0A1X9I714	Streptococcus_phage	3.0e-55	32.3
WP_013145709.1\|1226784_1228074_+	insulinase family protein	G3MBJ8	Bacillus_virus	1.3e-21	24.6
WP_013145708.1\|1228128_1228845_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_011230790.1\|1228907_1229156_+	DUF3243 domain-containing protein	NA	NA	NA	NA
WP_012820465.1\|1229584_1230865_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_011230791.1\|1231058_1231850_+	DUF3388 domain-containing protein	NA	NA	NA	NA
WP_013145707.1\|1231877_1232771_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011230793.1\|1232851_1233430_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_013523429.1\|1233456_1234701_+	competence/damage-inducible protein A	NA	NA	NA	NA
WP_013523431.1\|1235961_1237869_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.3e-35	28.6
WP_013522881.1\|1239331_1240594_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	6.5e-31	31.3
WP_013523433.1\|1240997_1242554_+	ribonuclease Y	NA	NA	NA	NA
WP_011230798.1\|1242655_1243450_+	TIGR00282 family metallophosphoesterase	NA	NA	NA	NA
WP_003251598.1\|1243578_1243839_+	stage V sporulation protein SpoVS	J9PTX7	Bacillus_phage	1.9e-09	43.8
WP_013523434.1\|1243931_1244855_+	membrane dipeptidase	NA	NA	NA	NA
WP_013523435.1\|1245010_1246783_+	2-oxoacid:acceptor oxidoreductase subunit alpha	NA	NA	NA	NA
WP_011230801.1\|1246749_1247616_+	2-oxoacid:ferredoxin oxidoreductase subunit beta	NA	NA	NA	NA
WP_013523436.1\|1247844_1249440_+\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_011230803.1\|1249417_1249849_+	YlbF family regulator	NA	NA	NA	NA
WP_013523437.1\|1250072_1250621_+\|coat	outer spore coat protein CotE	NA	NA	NA	NA
WP_013523438.1\|1250717_1253429_+	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	5.0e-36	24.8
WP_013523439.1\|1253443_1255336_+	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	1.4e-64	31.6
WP_013523440.1\|1255544_1256570_+	C40 family peptidase	A0A0A8WF62	Clostridium_phage	4.7e-19	45.2
WP_013523441.1\|1256820_1258317_-	BCCT family transporter	A0A2I7QNT1	Vibrio_phage	4.0e-27	26.7
WP_012820510.1\|1258600_1259881_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_5

2130264 : 2188211

Staphylococcus_phage(25.0%)

transposase,protease,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013524052.1\|2130264_2131923_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_012820647.1\|2132493_2133681_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_013524053.1\|2136196_2137360_-	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_013524054.1\|2137602_2138016_-	DUF1445 domain-containing protein	NA	NA	NA	NA
WP_013524055.1\|2137987_2140435_-	DEAD/DEAH box helicase family protein	A0A097BY72	Enterococcus_phage	3.6e-33	25.4
WP_013524056.1\|2140427_2140754_-	nucleoside triphosphate pyrophosphohydrolase	A0A2I7SAA6	Vibrio_phage	2.1e-05	40.8
WP_013524057.1\|2143195_2143558_+	hypothetical protein	NA	NA	NA	NA
WP_013524058.1\|2143678_2144158_+	hypothetical protein	NA	NA	NA	NA
WP_013524059.1\|2144344_2145316_-	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_013524060.1\|2145449_2146604_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_013524061.1\|2146600_2147350_-	trehalose utilization protein ThuA	NA	NA	NA	NA
WP_013524062.1\|2147468_2148548_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_013524063.1\|2148689_2149703_-	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	1.9e-33	32.0
WP_013524064.1\|2150120_2150558_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_013524065.1\|2150614_2151910_-	MHS family MFS transporter	NA	NA	NA	NA
WP_011231605.1\|2152068_2152515_-	MaoC family dehydratase N-terminal domain-containing protein	NA	NA	NA	NA
WP_013144974.1\|2152783_2153611_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_013524066.1\|2153626_2154934_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_013524067.1\|2155117_2156431_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013524068.1\|2156856_2157261_-	hypothetical protein	NA	NA	NA	NA
WP_015731725.1\|2157274_2158201_-	glutaminase A	NA	NA	NA	NA
WP_013144969.1\|2158371_2158947_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_015731726.1\|2159483_2159945_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_013524071.1\|2160554_2161601_-	hypothetical protein	NA	NA	NA	NA
WP_144319738.1\|2161679_2162087_-	hypothetical protein	NA	NA	NA	NA
WP_013524072.1\|2162083_2162239_-	hypothetical protein	NA	NA	NA	NA
WP_013522940.1\|2162404_2163577_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_013524073.1\|2165136_2166327_-	8-amino-7-oxononanoate synthase	G9E4Q1	Emiliania_huxleyi_virus	3.4e-37	27.5
WP_011231614.1\|2166533_2166716_+	small acid-soluble spore protein H	NA	NA	NA	NA
WP_013524074.1\|2166762_2166900_-	hypothetical protein	NA	NA	NA	NA
WP_013524075.1\|2166992_2167361_-	VOC family protein	NA	NA	NA	NA
WP_013524076.1\|2167357_2168140_-\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_013524077.1\|2168162_2168810_-	SdpI family protein	NA	NA	NA	NA
WP_013524078.1\|2168796_2169081_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013524079.1\|2169403_2170951_-	methylmalonyl-CoA decarboxylase	NA	NA	NA	NA
WP_013524080.1\|2171012_2172668_-	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	4.0e-36	28.7
WP_013524081.1\|2172921_2173437_-	DoxX family protein	NA	NA	NA	NA
WP_015731727.1\|2173864_2173960_-	hypothetical protein	NA	NA	NA	NA
WP_013524082.1\|2174148_2176017_+	hypothetical protein	NA	NA	NA	NA
WP_013524083.1\|2176013_2176640_+	hypothetical protein	NA	NA	NA	NA
WP_011230640.1\|2176764_2177160_+	hypothetical protein	NA	NA	NA	NA
WP_013524084.1\|2177274_2179293_+	ABC transporter permease	NA	NA	NA	NA
WP_013524085.1\|2179276_2180143_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	6.3e-25	33.8
WP_013524086.1\|2180135_2180768_+	hypothetical protein	NA	NA	NA	NA
WP_013524087.1\|2180839_2182081_+	aminopeptidase	NA	NA	NA	NA
WP_013524088.1\|2182184_2184998_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_013524089.1\|2185238_2185433_-	hypothetical protein	S6C469	Thermus_phage	8.7e-28	93.8
WP_013524090.1\|2185429_2186092_-\|capsid	minor capsid protein	S6B1L4	Thermus_phage	1.7e-94	76.4
WP_013523632.1\|2186930_2188211_-\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

2258301 : 2269000

Pandoravirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013144898.1\|2258301_2259321_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	1.9e-68	44.0
WP_013524131.1\|2259314_2260841_-	anthranilate synthase component I	S4VNU7	Pandoravirus	8.2e-36	37.4
WP_013144896.1\|2261076_2261457_-	chorismate mutase	NA	NA	NA	NA
WP_013144895.1\|2261453_2262554_-	3-dehydroquinate synthase	E5ERI4	Ostreococcus_lucimarinus_virus	9.1e-21	30.7
WP_011231692.1\|2262556_2263723_-	chorismate synthase	A0A291AU41	Pandoravirus	2.0e-42	36.5
WP_011231693.1\|2263821_2264592_-	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_013524132.1\|2264664_2265114_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	46.2
WP_013524133.1\|2265212_2266175_-	heptaprenyl diphosphate synthase component II	A0A1V0SE37	Indivirus	2.1e-05	23.5
WP_011231696.1\|2266190_2266895_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_013524134.1\|2266899_2267733_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_011231698.1\|2267795_2268020_-	trp RNA-binding attenuation protein MtrB	NA	NA	NA	NA
WP_013144889.1\|2268032_2268599_-	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	4.8e-50	57.3
WP_008879623.1\|2268727_2269000_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	3.5e-30	78.9

DBSCAN-SWA_7

2330922 : 2340775

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012820699.1\|2330922_2332071_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	3.9e-22	33.6
WP_012820698.1\|2332420_2333734_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	3.0e-39	44.1
WP_012820697.1\|2334090_2334492_-	hypothetical protein	NA	NA	NA	NA
WP_033005253.1\|2334510_2335164_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.3e-14	35.3
WP_033005256.1\|2335343_2336099_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	9.4e-09	24.5
WP_012820694.1\|2336294_2336834_+	DUF309 domain-containing protein	NA	NA	NA	NA
WP_012820693.1\|2336856_2337213_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011231776.1\|2337334_2337799_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.0e-42	61.1
WP_012820692.1\|2337819_2339013_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	9.6e-117	53.8
WP_012820691.1\|2339033_2339678_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.4e-40	42.3
WP_012820690.1\|2339632_2340775_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	6.9e-56	36.5

DBSCAN-SWA_8

2383760 : 2413953

Synechococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023633822.1\|2383760_2385428_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_012820529.1\|2385713_2387372_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_012820650.1\|2387638_2388298_-	elongation factor G-binding protein	NA	NA	NA	NA
WP_012820626.1\|2388632_2390006_-\|transposase	IS1380 family transposase	NA	NA	NA	NA
WP_012820648.1\|2392977_2393778_+	AAA family ATPase	NA	NA	NA	NA
WP_012820647.1\|2396375_2397563_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_012820646.1\|2401366_2402776_-	NADP-dependent phosphogluconate dehydrogenase	V5UT40	Synechococcus_phage	1.5e-39	34.1
WP_012820645.1\|2402937_2403129_-	hypothetical protein	NA	NA	NA	NA
WP_012820644.1\|2403211_2403697_-	purine-binding chemotaxis protein CheW	NA	NA	NA	NA
WP_012820643.1\|2403813_2404938_-	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_012820642.1\|2406050_2406458_-	hypothetical protein	NA	NA	NA	NA
WP_012820640.1\|2408480_2408942_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_012820639.1\|2409081_2410269_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_012820638.1\|2410741_2411632_+	permease	NA	NA	NA	NA
WP_012820637.1\|2411647_2411800_+	hypothetical protein	NA	NA	NA	NA
WP_012820636.1\|2412702_2413953_+\|transposase	IS481 family transposase	M4T586	Rhodobacter_phage	3.3e-11	26.8

DBSCAN-SWA_9

2683127 : 2742941

Clostridium_phage(20.0%)

protease,coat,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013524229.1\|2683127_2684744_-\|coat	SafA/ExsA family spore coat assembly protein	NA	NA	NA	NA
WP_013524230.1\|2684902_2686006_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_013524231.1\|2686020_2686851_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_173346439.1\|2686879_2688472_-	L-aspartate oxidase	NA	NA	NA	NA
WP_013524233.1\|2688541_2689666_+	IscS subfamily cysteine desulfurase	NA	NA	NA	NA
WP_013144620.1\|2689681_2690221_+	transcription repressor NadR	NA	NA	NA	NA
WP_011232080.1\|2690329_2691178_-	prephenate dehydratase	NA	NA	NA	NA
WP_011232081.1\|2691199_2691643_-	ACT domain-containing protein	NA	NA	NA	NA
WP_011232082.1\|2691659_2692958_-	GTPase ObgE	NA	NA	NA	NA
WP_013524234.1\|2693195_2693744_-	Spo0B domain-containing protein	NA	NA	NA	NA
WP_011232084.1\|2693913_2694204_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_011232085.1\|2694219_2694549_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_011232086.1\|2694551_2694860_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_013144618.1\|2695351_2696212_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_013524235.1\|2696204_2696972_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_013144615.1\|2697234_2698038_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_020278403.1\|2698040_2698724_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_013144613.1\|2698773_2699292_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_013144612.1\|2699288_2700155_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_011232093.1\|2700174_2701197_-	rod shape-determining protein	NA	NA	NA	NA
WP_172643493.1\|2701354_2702026_-	DNA repair protein RadC	NA	NA	NA	NA
WP_013524238.1\|2702171_2702747_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_013524239.1\|2703177_2704293_-	hypothetical protein	NA	NA	NA	NA
WP_011232097.1\|2704409_2704871_-	type II secretion system protein	NA	NA	NA	NA
WP_013524240.1\|2704892_2705612_-	hypothetical protein	NA	NA	NA	NA
WP_013144607.1\|2705608_2706184_-	fimbrial protein	NA	NA	NA	NA
WP_013144606.1\|2706173_2707112_-	pilus assembly protein PilM	NA	NA	NA	NA
WP_013524241.1\|2707133_2707889_-	prepilin peptidase	NA	NA	NA	NA
WP_013524242.1\|2707948_2708467_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_013524243.1\|2708552_2709764_-	type II secretion system F family protein	NA	NA	NA	NA
WP_013524244.1\|2709750_2710806_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_013524245.1\|2710818_2712480_-	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_013524246.1\|2712513_2713842_-	VanW family protein	NA	NA	NA	NA
WP_013144599.1\|2713858_2714638_-	PRC-barrel domain-containing protein	NA	NA	NA	NA
WP_013524247.1\|2714627_2716244_-	hypothetical protein	NA	NA	NA	NA
WP_013524248.1\|2716387_2717008_+	type II secretion system protein	NA	NA	NA	NA
WP_013524249.1\|2716991_2717570_+	hypothetical protein	NA	NA	NA	NA
WP_013524250.1\|2717613_2719320_+	hypothetical protein	NA	NA	NA	NA
WP_013524251.1\|2719414_2722648_-	VWA domain-containing protein	A0A1L2BYA9	Clostridium_phage	1.1e-08	31.3
WP_013524252.1\|2722716_2724012_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_013524253.1\|2724228_2726871_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	1.2e-164	42.4
WP_011232115.1\|2727346_2727535_+	hypothetical protein	NA	NA	NA	NA
WP_013524254.1\|2727572_2728604_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_013144590.1\|2728647_2729703_-	stage VI sporulation protein D	NA	NA	NA	NA
WP_013524255.1\|2729821_2731111_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_013144588.1\|2731127_2732102_-	porphobilinogen synthase	NA	NA	NA	NA
WP_013524256.1\|2732102_2732870_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_013144586.1\|2732866_2733799_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_013524257.1\|2733814_2734633_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_013524258.1\|2734643_2736008_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_013144583.1\|2736174_2736660_+	hypothetical protein	NA	NA	NA	NA
WP_013144582.1\|2736701_2737289_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_031212304.1\|2737285_2739628_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	1.9e-172	43.2
WP_013144580.1\|2739858_2741532_-\|protease	ATP-dependent protease LonB	A0A076FMQ5	Aureococcus_anophage	1.1e-12	32.7
WP_011232128.1\|2741675_2742941_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	6.3e-151	67.0

DBSCAN-SWA_10

2909525 : 3009520

110

Geobacillus_virus(23.73%)

tRNA,capsid,transposase,holin,tail,head,portal,terminase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013524357.1\|2909525_2910713_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_041469272.1\|2910687_2911209_-	hypothetical protein	NA	NA	NA	NA
WP_013523048.1\|2911359_2912238_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_012820647.1\|2912720_2913908_+\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_013524358.1\|2914261_2915533_-	MFS transporter	NA	NA	NA	NA
WP_013524359.1\|2916827_2917820_-	catabolite control protein A	NA	NA	NA	NA
WP_013144453.1\|2918124_2919207_-	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	E3T537	Cafeteria_roenbergensis_virus	4.3e-15	28.9
WP_013524360.1\|2919418_2919748_-	bacillithiol system redox-active protein YtxJ	NA	NA	NA	NA
WP_013524361.1\|2919753_2920149_-	YtxH domain-containing protein	NA	NA	NA	NA
WP_013524362.1\|2920164_2920578_-	DUF948 domain-containing protein	NA	NA	NA	NA
WP_011232289.1\|2920723_2922028_-	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_013524363.1\|2922186_2924541_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	2.8e-91	50.3
WP_013524364.1\|2924647_2925253_-	DUF4479 domain-containing protein	NA	NA	NA	NA
WP_013524365.1\|2925273_2926071_-	DUF1444 domain-containing protein	A0A2H4PQY3	Staphylococcus_phage	1.5e-36	56.9
WP_013524366.1\|2926067_2926259_-	hypothetical protein	NA	NA	NA	NA
WP_013524367.1\|2926299_2926830_-	DUF84 family protein	NA	NA	NA	NA
WP_041469267.1\|2926875_2927952_-	M42 family metallopeptidase	NA	NA	NA	NA
WP_013524369.1\|2928067_2928367_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_013524370.1\|2928361_2929210_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_013524371.1\|2929290_2929944_-\|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_013524372.1\|2930152_2930422_+	hypothetical protein	NA	NA	NA	NA
WP_013524373.1\|2930531_2931314_-	phosphotransferase family protein	NA	NA	NA	NA
WP_013524374.1\|2931622_2933779_-	type I pullulanase	NA	NA	NA	NA
WP_013524375.1\|2933880_2934819_-	hypothetical protein	NA	NA	NA	NA
WP_013524376.1\|2934830_2935409_-	RNA 2',3'-cyclic phosphodiesterase	NA	NA	NA	NA
WP_013524377.1\|2935405_2936590_-	MFS transporter	NA	NA	NA	NA
WP_083777766.1\|2936658_2938074_-	dipeptidase PepV	NA	NA	NA	NA
WP_008880936.1\|2938327_2938549_+	DeoR family transcriptional regulator	NA	NA	NA	NA
WP_013524379.1\|2938643_2939390_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_011232307.1\|2939494_2939707_+	hypothetical protein	NA	NA	NA	NA
WP_013524380.1\|2939924_2941550_-	polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_013524381.1\|2941662_2942973_+	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	2.2e-29	58.9
WP_008880941.1\|2943167_2943347_-	sporulation protein Cse60	NA	NA	NA	NA
WP_013524383.1\|2943462_2945103_-	peptidase M4 family protein	NA	NA	NA	NA
WP_013524385.1\|2945625_2946900_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013144427.1\|2947245_2947560_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	2.1e-15	47.9
WP_013524386.1\|2947617_2950035_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	74.5
WP_013524387.1\|2950422_2951622_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	3.2e-96	46.4
WP_013144424.1\|2951832_2951997_-	hypothetical protein	NA	NA	NA	NA
WP_011232317.1\|2952015_2952279_-	YtzC family protein	NA	NA	NA	NA
WP_013524388.1\|2952571_2953159_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.5e-42	45.7
WP_041468697.1\|2953216_2954299_-	tetraprenyl-beta-curcumene synthase family protein	NA	NA	NA	NA
WP_013144421.1\|2954664_2955213_+	gamma carbonic anhydrase family protein	NA	NA	NA	NA
WP_013524389.1\|2955235_2956447_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.3e-164	75.9
WP_013524390.1\|2956909_2958496_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	5.6e-197	64.6
WP_013523048.1\|2961523_2962402_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_013524391.1\|2964157_2965060_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_013524392.1\|2965339_2965582_-	DUF2584 domain-containing protein	NA	NA	NA	NA
WP_013524393.1\|2965674_2966463_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.4e-34	38.1
WP_013524395.1\|2967399_2967996_-	replication-relaxation family protein	A0A0S2SXR2	Bacillus_phage	1.2e-27	45.3
WP_013524396.1\|2967943_2969104_-	cell division protein FtsK	A0A0A0RNH5	Bacillus_phage	1.2e-116	55.3
WP_013524397.1\|2969234_2969405_-	hypothetical protein	U5PZ86	Bacillus_phage	5.7e-07	51.9
WP_015731621.1\|2969401_2969785_-	hypothetical protein	A0A0S2SXN6	Bacillus_phage	4.6e-12	40.2
WP_013524399.1\|2970021_2970228_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013524400.1\|2970220_2970706_+	PH domain-containing protein	A0A0D4DCT6	Staphylococcus_phage	2.9e-27	41.9
WP_013524401.1\|2970771_2971452_-	N-acetylmuramoyl-L-alanine amidase	Q0H257	Geobacillus_phage	8.7e-115	92.4
WP_013524402.1\|2971451_2971865_-\|holin	holin family protein	Q0H258	Geobacillus_phage	1.1e-40	62.8
WP_013524403.1\|2971900_2973046_-	siphovirus ReqiPepy6 Gp37-like family protein	A0A0K2CZQ1	Paenibacillus_phage	4.5e-87	43.0
WP_013524404.1\|2973117_2973381_-	hypothetical protein	A0A2H4J342	uncultured_Caudovirales_phage	4.8e-13	50.8
WP_013524405.1\|2973380_2973854_-	hypothetical protein	A0A2H4J062	uncultured_Caudovirales_phage	9.4e-07	45.6
WP_013524406.1\|2973856_2974186_-	hypothetical protein	NA	NA	NA	NA
WP_013524407.1\|2974186_2975089_-	hypothetical protein	A0A0C5ABC3	Paenibacillus_phage	5.1e-62	65.9
WP_013524408.1\|2975091_2975955_-\|tail	phage tail family protein	A0A2I7SBZ7	Paenibacillus_phage	4.1e-77	52.1
WP_013524410.1\|2979899_2980862_-	DUF2726 domain-containing protein	A0A286QSF4	Streptococcus_phage	1.1e-57	39.1
WP_013524412.1\|2982189_2982480_-	hypothetical protein	NA	NA	NA	NA
WP_013524413.1\|2982535_2983105_-\|tail	phage tail protein	A0A2I7SBZ0	Paenibacillus_phage	2.2e-42	45.9
WP_013524414.1\|2983125_2983449_-	hypothetical protein	A0A0S2SY15	Bacillus_phage	8.0e-18	46.3
WP_013524415.1\|2983445_2983805_-	HK97 gp10 family phage protein	H0USW9	Bacillus_phage	1.9e-15	41.0
WP_013524416.1\|2983806_2984136_-\|head	phage head closure protein	A0A0K2CZB5	Paenibacillus_phage	1.4e-30	63.3
WP_013524417.1\|2984132_2984411_-\|head,tail	phage gp6-like head-tail connector protein	A6M953	Geobacillus_virus	1.3e-35	73.4
WP_013524418.1\|2984407_2984569_-	hypothetical protein	A6M952	Geobacillus_virus	3.4e-09	64.4
WP_013524419.1\|2984611_2985718_-\|capsid	phage major capsid protein	A6M951	Geobacillus_virus	1.4e-157	79.0
WP_013524420.1\|2985758_2986493_-\|protease	Clp protease ClpP	A6M950	Geobacillus_virus	2.0e-117	87.7
WP_013524421.1\|2986492_2987734_-\|portal	phage portal protein	A6M949	Geobacillus_virus	1.4e-206	84.8
WP_013524422.1\|2987767_2987962_-	hypothetical protein	NA	NA	NA	NA
WP_013524423.1\|2987966_2989667_-\|terminase	terminase large subunit	A0A0S2GLF0	Bacillus_phage	3.7e-263	77.6
WP_013524424.1\|2989666_2990164_-\|terminase	phage terminase small subunit P27 family	A6M947	Geobacillus_virus	5.9e-60	70.6
WP_013524425.1\|2990253_2990661_-	HNH endonuclease	A0A1U7Q1S7	Geobacillus_virus	1.4e-46	69.2
WP_013524426.1\|2990708_2990927_-	hypothetical protein	NA	NA	NA	NA
WP_013524428.1\|2991437_2991656_-	hypothetical protein	NA	NA	NA	NA
WP_144319757.1\|2991671_2992100_-	ArpU family transcriptional regulator	S6AVV9	Thermus_phage	7.8e-61	84.4
WP_013524430.1\|2992217_2992460_-	helix-hairpin-helix domain-containing protein	A0A1L2K2L4	Aeribacillus_phage	1.5e-21	62.4
WP_013524431.1\|2992459_2992597_-	hypothetical protein	NA	NA	NA	NA
WP_013524432.1\|2992612_2993143_-	hypothetical protein	S6C473	Thermus_phage	3.6e-31	41.5
WP_013524433.1\|2993199_2993520_-	hypothetical protein	E5DV93	Deep-sea_thermophilic_phage	5.5e-43	84.5
WP_015731618.1\|2993516_2993819_-	hypothetical protein	NA	NA	NA	NA
WP_013524435.1\|2993832_2994387_-	dUTP diphosphatase	A6M995	Geobacillus_virus	8.8e-65	71.8
WP_013524439.1\|2995044_2995872_-	ATP-binding protein	S6B1M2	Thermus_phage	7.8e-134	85.4
WP_013524440.1\|2995813_2996734_-	HTH domain-containing protein	S6BFM4	Thermus_phage	1.3e-142	96.1
WP_013524442.1\|2996909_2997755_-	recombination protein RecT	S6AVW6	Thermus_phage	1.4e-154	97.5
WP_013524443.1\|2997770_2997947_-	hypothetical protein	S6B9Z6	Thermus_phage	2.3e-27	96.6
WP_013524444.1\|2997956_2998892_-	YqaJ viral recombinase family protein	S6C475	Thermus_phage	5.0e-161	92.6
WP_013524445.1\|2999001_2999202_-	hypothetical protein	S6B1M6	Thermus_phage	8.7e-31	92.3
WP_013524446.1\|2999258_2999474_-	hypothetical protein	NA	NA	NA	NA
WP_013524447.1\|2999473_2999737_-	hypothetical protein	A6XMM3	Bacillus_virus	1.5e-17	48.3
WP_013524448.1\|2999757_3000006_-	AbrB family transcriptional regulator	A6M978	Geobacillus_virus	1.4e-33	86.6
WP_013524449.1\|3000002_3000782_-	Rha family transcriptional regulator	A6M977	Geobacillus_virus	3.0e-87	71.7
WP_013524450.1\|3000832_3001012_-	hypothetical protein	A6M976	Geobacillus_virus	1.5e-21	86.4
WP_013524452.1\|3001250_3001469_-	XRE family transcriptional regulator	A6M975	Geobacillus_virus	1.2e-28	100.0
WP_013524453.1\|3001671_3002349_+	helix-turn-helix domain-containing protein	A6M973	Geobacillus_virus	2.8e-121	95.6
WP_013524454.1\|3002418_3003807_+	recombinase family protein	A6M972	Geobacillus_virus	8.0e-232	89.0
WP_013524455.1\|3004529_3005321_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.6e-35	36.7
WP_013524456.1\|3005304_3006114_+	ABC transporter permease	NA	NA	NA	NA
WP_013524457.1\|3006232_3006700_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	1.7e-21	38.3
WP_013524458.1\|3006758_3007091_-	hypothetical protein	NA	NA	NA	NA
WP_013524459.1\|3007152_3007548_-\|holin	phage holin family protein	A0A0N7GFE6	Paenibacillus_phage	9.2e-24	48.3
WP_013524460.1\|3007700_3008141_-	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	9.5e-54	67.8
WP_015731617.1\|3008406_3008565_+	YtzI protein	NA	NA	NA	NA
WP_013524462.1\|3008587_3009064_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_013524463.1\|3009277_3009520_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	4.9e-20	70.5

DBSCAN-SWA_11

3242778 : 3251241

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013524614.1\|3242778_3244419_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	2.2e-47	29.8
WP_013524615.1\|3244490_3244784_-	transporter	NA	NA	NA	NA
WP_013524616.1\|3244983_3246282_-	peptidoglycan DD-metalloendopeptidase family protein	A0A222YZS8	Streptomyces_phage	8.0e-16	44.5
WP_013146410.1\|3246310_3247204_-	ABC transporter permease	NA	NA	NA	NA
WP_011232571.1\|3247184_3247880_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	7.0e-27	36.3
WP_013524617.1\|3248140_3248476_-	cytochrome c	NA	NA	NA	NA
WP_013524618.1\|3248537_3249401_-	YitT family protein	NA	NA	NA	NA
WP_013524619.1\|3249538_3249799_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A125RQ76	Bacillus_phage	1.9e-30	70.9
WP_011232575.1\|3249767_3250028_-	hypothetical protein	A0A125RQ77	Bacillus_phage	4.2e-17	52.9
WP_164834641.1\|3250139_3251241_-	peptide chain release factor 2	A0A0S4KWG0	Pseudomonas_phage	2.4e-05	39.0

DBSCAN-SWA_12

3598967 : 3608725

uncultured_Mediterranean_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011232933.1\|3598967_3600188_-	trypsin-like peptidase domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	6.1e-18	28.8
WP_013146695.1\|3600289_3601084_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	6.5e-45	37.7
WP_013146696.1\|3601090_3601873_-	two-component system regulatory protein YycI	NA	NA	NA	NA
WP_013524876.1\|3601859_3603188_-	hypothetical protein	NA	NA	NA	NA
WP_013524877.1\|3603180_3605010_-	cell wall metabolism sensor histidine kinase WalK	A0A1V0SGX0	Hokovirus	1.6e-22	27.0
WP_013524878.1\|3605016_3605730_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.2e-44	41.4
WP_013524879.1\|3605918_3607205_-	adenylosuccinate synthase	A0A2P1EKE7	Megavirus	6.6e-71	36.7
WP_011232940.1\|3607360_3608725_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	7.9e-123	52.8

Anti-CRISPR protein detection

Acr_ID: NC_014915.1|WP_008880941.1|2943167_2943347_-|sporulation-protein-Cse60

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_014915.1|WP_008880941.1|2943167_2943347_-|sporulation-protein-Cse60

2943167_2943347_-

59 aa aa

2909525-3009520

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_014915_3	TypeIII	3.20\|364790\|35\|NC_014915\|PILER-CR,CRISPRCasFinder,CRT	364790-364824	35	3001657-3001691	0

1. spacer 3.20|364790|35|NC_014915|PILER-CR,CRISPRCasFinder,CRT matches to NC_014915 position: 3001657-3001691, mismatch: 0

aaggaggtgatagaagtgacaaaagaagagattgt	CRISPR spacer
aaggaggtgatagaagtgacaaaagaagagattgt	Protospacer
***********************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_014915

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information