CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NZ_CP002007	Streptococcus suis 05HAS68 chromosome, complete genome	2 crisprs	DinG,cas1,cas2,csn2,csa3,cas3,DEDDh	1	6	10	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NZ_CP002007_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP002007_1

888781-889276

TypeII-A

Consensus_repeat	Method
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	CRISPRCasFinder
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	CRT
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	PILER-CR

7 spacers

csn2,cas2,cas1

The CRISPR arrays of NZ_CP002007_1

>merge|NZ_CP002007|1|888781-889276|CRISPRCasFinder,CRT,PILER-CR
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAACTGGCCAAACGTGGGATCAAAACCATGTTGGTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAACCTAAGATAAATAATATCCCAATTAATACTGGTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAACTAATTATCTCTTTGGACCGCATCGTGGCCAGTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAACGGATTATTGAGTGGGTTAACATCTGCAGGGTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAACAACATCAATGTATTTCTTTTCGACCTTGTCGTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAACCACTTCCTTACGCTACTAATTTTCAGTTAAGTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAACCTTCTGGTAGTTATCCCCATAACATTTGTAGTTTTTGTACTCTCAAGATTTATATTATCGTAATCA

>NZ_CP002007|1|1|888781-889276|CRISPRCasFinder
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	TGGCCAAACGTGGGATCAAAACCATGTTG
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	CTAAGATAAATAATATCCCAATTAATACTG
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	TAATTATCTCTTTGGACCGCATCGTGGCCA
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	GGATTATTGAGTGGGTTAACATCTGCAGG
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	AACATCAATGTATTTCTTTTCGACCTTGTC
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	CACTTCCTTACGCTACTAATTTTCAGTTAA
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	CTTCTGGTAGTTATCCCCATAACATTTGTA
GTTTTTGTACTCTCAAGATTTATATTATCGTAATCA

>NZ_CP002007|1|1|888781-889276|CRT
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	TGGCCAAACGTGGGATCAAAACCATGTTG
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	CTAAGATAAATAATATCCCAATTAATACTG
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	TAATTATCTCTTTGGACCGCATCGTGGCCA
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	GGATTATTGAGTGGGTTAACATCTGCAGG
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	AACATCAATGTATTTCTTTTCGACCTTGTC
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	CACTTCCTTACGCTACTAATTTTCAGTTAA
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	CTTCTGGTAGTTATCCCCATAACATTTGTA
GTTTTTGTACTCTCAAGATTTATATTATCGTAATCA

>NZ_CP002007|1|1|888978-889210|PILER-CR
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	GGATTATTGAGTGGGTTAACATCTGCAGG
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	AACATCAATGTATTTCTTTTCGACCTTGTC
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC	CACTTCCTTACGCTACTAATTTTCAGTTAA
GTTTTTGTACTCTCAAGATTTAAGTAACAGTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP002007.2\|WP_002935600.1\|886442_887357_+\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NZ_CP002007.2\|WP_009910389.1\|891591_891948_+\|ArsC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|239332
NZ_CP002007.2\|WP_002935599.1\|887353_887677_+\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NZ_CP002007.2\|WP_002935569.1\|898851_899469_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|240029
NZ_CP002007.2\|WP_009910392.1\|878181_878490_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP002007.2\|WP_024395102.1\|890380_891592_+\|phosphopentomutase	unknown	unknown	gnl\|CDD\|235430
NZ_CP002007.2\|WP_002935570.1\|898124_898865_+\|acyl-ACP-thioesterase	unknown	unknown	gnl\|CDD\|366738
NZ_CP002007.2\|WP_002935571.1\|896766_897894_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NZ_CP002007.2\|WP_002935611.1\|878611_879688_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP002007.2\|WP_002935618.1\|876629_878093_+\|flotillin-family-protein	unknown	unknown	gnl\|CDD\|259798
NZ_CP002007.2\|WP_002935608.1\|879799_881173_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NZ_CP002007.2\|WP_002935621.1\|876036_876618_+\|LemA-family-protein	unknown	unknown	gnl\|CDD\|377192
NZ_CP002007.2\|WP_158469063.1\|885988_886276_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP002007.2\|WP_024409330.1\|885034_885979_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NZ_CP002007.2\|WP_002935585.1\|891959_892769_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|236183
NZ_CP002007.2\|WP_002935583.1\|892801_893515_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NZ_CP002007.2\|WP_002935598.1\|887673_888720_+\|hypothetical-protein	csn2	cd12217_csn2_CAS-II-A	gnl\|CDD\|213410
NZ_CP002007.2\|WP_002935572.1\|896093_896672_-\|VanZ-family-protein	unknown	unknown	gnl\|CDD\|377417
NZ_CP002007.2\|WP_013730441.1\|889377_890052_+\|ribose-5-phosphate-isomerase-RpiA	unknown	unknown	gnl\|CDD\|234816
NZ_CP002007.2\|WP_009910385.1\|893691_895959_+\|glycogen/starch/alpha-glucan-family-phosphorylase	unknown	unknown	gnl\|CDD\|340853

Protein	Function_ID	Function_description	E-value
NZ_CP002007.2\|WP_002935600.1\|886442_887357_+\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	2.0775e-122
NZ_CP002007.2\|WP_009910389.1\|891591_891948_+\|ArsC-family-transcriptional-regulator	gnl\|CDD\|239332	cd03034, ArsC_ArsC, Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the detoxification of arsenic, using reducing equivalents derived from glutathione (GSH) via glutaredoxin (GRX). ArsC contains a single catalytic cysteine, within a thioredoxin fold, that forms a covalent thiolate-As(V) intermediate, which is reduced by GRX through a mixed GSH-arsenate intermediate. This family of predominantly bacterial enzymes is unrelated to two other families of arsenate reductases which show similarity to low-molecular-weight acid phosphatases and phosphotyrosyl phosphatases.	1.01834e-20
NZ_CP002007.2\|WP_002935599.1\|887353_887677_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.7745e-25
NZ_CP002007.2\|WP_002935569.1\|898851_899469_+\|NUDIX-hydrolase	gnl\|CDD\|240029	cd04672, Nudix_Hydrolase_14, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	3.31442e-61
NZ_CP002007.2\|WP_024395102.1\|890380_891592_+\|phosphopentomutase	gnl\|CDD\|235430	PRK05362, PRK05362, phosphopentomutase; Provisional.	0
NZ_CP002007.2\|WP_002935570.1\|898124_898865_+\|acyl-ACP-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	7.63063e-88
NZ_CP002007.2\|WP_002935571.1\|896766_897894_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NZ_CP002007.2\|WP_002935585.1\|891959_892769_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|236183	PRK08202, PRK08202, purine nucleoside phosphorylase; Provisional.	6.03224e-162
NZ_CP002007.2\|WP_002935618.1\|876629_878093_+\|flotillin-family-protein	gnl\|CDD\|259798	cd03399, SPFH_flotillin, Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. The flotillin (reggie) like proteins are lipid raft-associated. Individual proteins of this SPFH family may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. In addition, microdomains formed from flotillin proteins may be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and interact with a variety of proteins. They may play a role in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease and in cancer invasion, and metastasis.	7.80101e-47
NZ_CP002007.2\|WP_002935608.1\|879799_881173_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NZ_CP002007.2\|WP_002935621.1\|876036_876618_+\|LemA-family-protein	gnl\|CDD\|377192	pfam04011, LemA, LemA family. The members of this family are related to the LemA protein. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain.	8.85941e-67
NZ_CP002007.2\|WP_024409330.1\|885034_885979_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	1.33167e-53
NZ_CP002007.2\|WP_002935572.1\|896093_896672_-\|VanZ-family-protein	gnl\|CDD\|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	9.00811e-06
NZ_CP002007.2\|WP_002935583.1\|892801_893515_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	4.90632e-151
NZ_CP002007.2\|WP_002935598.1\|887673_888720_+\|hypothetical-protein	gnl\|CDD\|213410	cd12217, Stu0660_Csn2, Stu0660-like CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. This family of Csn2 proteins includes Stu0660, the proteins are larger than other (canonical) Csn2 proteins as they have an additional alpha-helical C-terminal domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	2.6417e-137
NZ_CP002007.2\|WP_013730441.1\|889377_890052_+\|ribose-5-phosphate-isomerase-RpiA	gnl\|CDD\|234816	PRK00702, PRK00702, ribose-5-phosphate isomerase RpiA.	3.34018e-113
NZ_CP002007.2\|WP_009910385.1\|893691_895959_+\|glycogen/starch/alpha-glucan-family-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0

>NZ_CP002007.2|WP_002935598.1|887673_888720_+|hypothetical-protein
MKWLITHHVLNNIPIHVGQFTQIVGQNYELKYYIWQILIWYFGGKKYSEEDLILFNQEEPVISQDSEAIKRNAFKIISIAEVGDILEQISYKKGTIGFSYLSLKMQNIEIIEELEILNYHLHKIAQKVNSSISLINDEIEYEVGTTDLLPEQILTKQLTPHFKKSRDEIAIEFISNEKKLCFLLQMLNAIMQEQTKPILLVLKNLDDYLTYDSFVRIAQYLEELSNKYPYFNTILFPSQEGYLYLTEATLETVNIVSDRIEHYPAFTFLYTRYQQSYPSTSPLGEKEFLNSLRKISSYLFSSDINRVVSLADIDLVTLKIVNSLYQYDIKMVYMYKGISKLEENYLSS
>NZ_CP002007.2|WP_002935599.1|887353_887677_+|CRISPR-associated-endonuclease-Cas2
MRYDAMRLLCFFDLPMETTQEKRQYRLFRKELIANGFEMLQFSVYYRTCPNRSFATKFYKKLQQSHLPAGNVRLLAVTEKQFSEMVLIVGGKTRQEEAISDRKLVII
>NZ_CP002007.2|WP_002935600.1|886442_887357_+|type-II-CRISPR-associated-endonuclease-Cas1
MTWRIVHIHQSEKMRLKLDNLVIKKQGDEFTIPLSDISIIVAEGGDTVVTLRLLSALSKYNIALIVCDNHHLPTGIYHSQNGHFRAYKKLQAQLSWAPLQKDKLWQIIIYFKITNQQDVLAMQEKSLSTIQLLSDYREHIELGDRTNREGHAAKVYFNELFGKQFVRLTQQETDAVNAGLNYGYTIFRAQMARIIAGYGLNALIGIFHKNEYNQFNLADDLMEPFRQIVDVWVYMNLREADFLTYQHRLELTNLLNAKIRYGKENCSVTVAMDKFVKGFIRCIEDKDTNQFFCPVVSSLEMEKL
>NZ_CP002007.2|WP_158469063.1|885988_886276_+|hypothetical-protein
MGFIKDIENNFGKLLRFTSKNDTSKHYVELKPYDKNKFGTEEPLLPVLGNVAKSGRCIKGLNKSNISIYKVRTDILGYRHFIKQEGEHPQLKFKK
>NZ_CP002007.2|WP_024409330.1|885034_885979_+|IS30-family-transposase
MTYTHLTTNELVMIEAYYKEGIAVSHICQSLKRSRQTIHKVIAYLKAGHTAYDYYKDYKANKKRCGRRQTQLTQSEQDFIQRHLELNWSLDVVKGTYPDKIPCSMRTLYRLADRGIFKKVDLPWKGKRKPNGIAEKRGKQAFRRDIRERSEIYPDFDTEFGHLEGDTIVGKHHKSAVVTLVEKQSKAIITLQTNGRKASDIEQSLNRWLSQFPKHLFKSVTFDCGKEFSNWKTIANQHDIDIFFADPGCPGQRGLNEHSNGLLRRHGLPKQMDFNGIPQKYLSAITDKRNRIPRKSLNYRTPYQVFLSYVKCLA
>NZ_CP002007.2|WP_002935608.1|879799_881173_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MITKEFDTITAISTPLGEGAIGIVRLSGTDAFAIASKVFKGKDLATVPSHSLNYGHIIDPATGQVLDEVILGVMRSPKTFTREDVIEINTHGGIAVTNEILQLLIRQGARMAEPGEFTKRAFLNGRVDLTQAEAVMDVIRAKTDKAMHNAVRQLDGSLSQLINDTRQEILNTLAQVEVNIDYPEYDDVEEATTELVREKTLQFQALLENLLRTARRGKILREGIATAIIGRPNVGKSSLLNNLLREEKAIVTDIAGTTRDVIEEYVNIKGVPLKLIDTAGIRETDDIVEKIGVERSKKALEEADLILLVLNASEPLTEQDRNLLAISDLANRIVLLNKTDLEEQIEADQLPEDVIRISVLKNQNIDQIEEKINQLFFENAGLVEQDATYLSNSRHISLIEQAVQSLQAVNDGLEMGMPVDLLQVDLTRCWQILGEITGDAAPDELITQLFSQFCLGK
>NZ_CP002007.2|WP_002935611.1|878611_879688_-|hypothetical-protein
MKKLLICIVLLSCLVFPFIGWKLYAYQHNTITLTSEADFYLIYPGKVEAFQLNGQEPELLHTQKMNSEGYFGSGENYVIDSRYLVFANDQQKFINDNLISIDFNTGTVLRKPSQYSSYISGTDGQDFYTAGPYHILAQFDRNFDTIQTHVLNDDFIPNAPVMVDQTSVYLTGFVKDFTQEGPEENVLIVFDKKDFSKQEVFKYDNTIATGEGPWVNGTIYLPNLGKKTSEYTDIEQSSELLTFDTKTKTFSSVTLEHPSPSTLHALKDQKLLLIEHQNDMFSPISFTIYNTQTGQESYHRLDELNPRPYYIDHVRQLDGNRLLLILAGKALIYDWQAKKVLSQTILSENYVSGVWVND
>NZ_CP002007.2|WP_009910392.1|878181_878490_+|hypothetical-protein
MKMFRNSKKSKLFIQKINELLSDSELKLSKALKFQLLEAMELCEKGSKISYLSYKIYPWVLEELALNRIQSDKLKMFKRYLEQERWKYYFGSALGMAFTSIR
>NZ_CP002007.2|WP_002935618.1|876629_878093_+|flotillin-family-protein
MDFGFDILAIMIPIIVVVLFVLLFVFGYVSAKPNEAIVITGLGKPRTLIGRSGFMIPFIEKRSYISIEQFSTDVQTTDFVPTLDFINVKADAVVKVKVGISDELLNAAAQNFLNWKTADISASIQDVLEGNLREIIGQMELRDMVNNRQAFAEKVQSNAAPDLAKMGLEIIAFTVQSFTDDNDVIKNLGIDNIVTIQKDAANARAKAEREQAEVRAREDKAANDARVAADLEIAKKQNELAIEQANLKRQSDVQLAQANAAYGIEEQAQRKEIERATAEANIVKQQKEAEVKAEEVKVREQELSATIRKQAEAEKYARQQAAEADLIERQRKAEAELYETQREAEAQKARAEAAKYAAEQEAAGIEAKGRAEAEAIRLKLEAEAEGLSKKADAMAKFNDAAVTEMVVNVLPEIAKNIAAPLGNVDKITMYGEGNASKMVGDLMTTMDKTTEGLGLNVRDLISATLTGRAMSTGLLTAQETKEAEGDK
>NZ_CP002007.2|WP_002935621.1|876036_876618_+|LemA-family-protein
MKKKWLAILLPILALLFLGMGAVGQYNGLVDSYAEVENAQANVDTQLQRRYDLIPNVVAAVKGAMEHEEEIFTAIAEARAKIGSSQVGTSDYNQAQSQLDSAVSRLLVVAENYPQLTANQQVSALITELEGTENRILVARKDYNSVATTYNKKIKRFPTSIYANLFGYEKVELFQATNDAATTVPSVDLSDKE
>NZ_CP002007.2|WP_013730441.1|889377_890052_+|ribose-5-phosphate-isomerase-RpiA
MTNLKEQVGIKAAEFVTDGMIVGLGTGSTAYYFVQEIGRRVAEEGLQITGVTTSHATAEHAASLGIPLKNIDEVEYVDLTVDGADEVDGDFNGIKGGGAALLMEKVVAVNSKDCIWIVDESKVVQTLGAFKLPVEVVQYGAENLFRLFEKKGYRPSFRMRNGEKHITDMQNFIIDLDLRRIEDTYALAEELDRTVGVVEHGLFIGLISKVIVGTLEGPNIIEKK
>NZ_CP002007.2|WP_024395102.1|890380_891592_+|phosphopentomutase
MPKFKRVHLVVMDSVGIGAAPDSDKFFNAGVADTESDTLGHISEKAGLEVPNMTKIGLGNIPRDTALATVPAESHPTGYVTKLEEVSLGKDTMTGHWEIMGLNITEPFDTFWDGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFSRTANRHDYAVSPFKATVLNKLADAGVPTYSVGKISDIFNGSGITNDMGHTKSNMHGVDVLIDTLKLSDFEEGFSFTNLVDFDAVYGHRRNIEGYRDCLQEFDARIPEIIDNMREDDLLLITADHGNDPSYAGTDHTREYVPLLAYSKAFKGSGVLPVGHFADISATVAENFGVDTAMIGESFLSQLV
>NZ_CP002007.2|WP_009910389.1|891591_891948_+|ArsC-family-transcriptional-regulator
MEKLTVYYNPNCSKCKKLRILLSSQDMEVKWVNYLETPLRGAELTALLEKMGSQPSAVTRLKEEERLALSEEEIFERLVEEPATLNRPIIEREQTAFLCRPLEIIKEKMPEYDWSDYL
>NZ_CP002007.2|WP_002935585.1|891959_892769_+|purine-nucleoside-phosphorylase
MSLLAKINETKTFLEEKGLVKPEFGLILGSGLGELAQEVENAIVIDYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKALGCEGVIVTNAAGGIGYGPGTLMAITDHINMTGQNPLIGENLEEFGPRFPDMSNAYTKEYREKAHAVAEKLGIKLDDGVYLGVTGPTYETPAEILAFKTMGAHAVGMSTVPEVIVAAHSGMKVLGISAITNFAAGFQSELNHEEVVEVTEQIKGNFKGLVKAILAEL
>NZ_CP002007.2|WP_002935583.1|892801_893515_+|purine-nucleoside-phosphorylase
MSIHISAKPGEIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNMFGYTGTYKGHRVSVMGTGMGMPSISIYAHELINEYGVKKLIRVGTAGSLNEDVHVRELVLAQAAATNSRMINIDWPEYDLPQIADFDLLDKAYHIAKELNMTTHVGNVLSSDSFYSPKLFSRNLELGQLGVKAVEMEAAALYYLGAKFGVQTLAIMTISDSLVNPEENTTAEERQNTFTDMMKVGLETLIAE
>NZ_CP002007.2|WP_009910385.1|893691_895959_+|glycogen/starch/alpha-glucan-family-phosphorylase
MINLQNFVQSMYAKRIEDCTDQELYYALLAFTKQQSEAKYTNDQKKKVYYISAEFLIGKLLSNNLINLGLYDEVKSQLVAAGKDLIAIEDMELEPSLGNGGLGRLAACFLDSIASLGLNGDGVGLNYHFGLFRQLFEYHQQSAVPNEWITPRSWLTESPISYQVPFANFTLTSKLYDIDVPGYKMERKNRLRLFDLGSVDDNIIYDGIEFDKEDIFRNLTLFLYPDDSTDEGKVLRIFQQYFMVSNAAQLLIDEAVAKGSNLHDLPDYAVVQINDTHPSLVIPELIRLLELRGISFDEAVEIVKKMTAYTNHTILSEALEKWPLDFLNYVVPHLVPFIVELDRRAKEVKDDPAVNIIDEYGRVHMAHMDIHYGYSINGVAALHTEILKTSELKAFYELYPEKFNNKTNGITFRRWLMHANPSLASYLDGLLGHGYHHDASELEKLLDYKNDKELKSWLEKTKQHNKRKLQRHIAKTQGVHVNPESIFDVQIKRMHEYKRQQMNVLYVIHKYLDIKAGNIPTRPLTVFFGGKAAPAYTTAQDIIHLILVLSQVIKNDSEVAPHLQLVMIENYNVTEASFIIPAADISEQISLASKEASGTGNMKFMLNGALTIGTDDGANVEIHELVGDENIYIFGQDSQTVIEHYANRTYHPYSFYEREVIRPLIDFITSDTIRHAGGIDERLWRLQDNLKHNDHFMTLLDLEDYIVTKERMLADYEDRDSWLEKVIVNIAKAGFFSSDRTIQQYNEDIWHLEAK
>NZ_CP002007.2|WP_002935572.1|896093_896672_-|VanZ-family-protein
MKKEIIYDCINLILSFLLCRWLFMTFLFYQFSNIFMTIDFWPTLAAILLMTGFCFTLFRLVYKPHISRLTLWFFYACYGLLLVYLLFFKSMGVRGVNWNLLSTFSQDLFLNPTILVFNLLLFLPLGLLFSFSWKKLSLFVGAILLVEACQFFFSLGFFDLGDILLNTSGFALGNFLGQSAIAQSFKNRIQKK
>NZ_CP002007.2|WP_002935571.1|896766_897894_+|oxygen-independent-coproporphyrinogen-III-oxidase
MKKRPTSAYIHIPFCTQICYYCDFSKVFIKNQPVDEYLAALMEEVKFYDLPALRTLYIGGGTPSALSADQLDYLLTNLEDLLDLSQLEEFTIEANPGDLTADKIAVLKKSKCNRVSLGVQTFDDRMLKKIGRSHNQAQIYETIATLKEAGFYNISIDLIYALPGQTMEQVVDNVAKALELDIPHMSLYSLILENHTVFMNRQRRGNLHLPNEDVESDMFDYILQELEKNGFEHYEISNFTKPGFESRHNLMYWDNSEYYGLGAGASGYIDGMRYRNRGPIQHYLKSIREKGHSRLHEEFLSQTEQMEEEMFLGLRKKTGVSIERFEEKFGISFEDRYGQVVRDLKNEGLLQEEDRWLRMTKKGLFLGDTVAERFI
>NZ_CP002007.2|WP_002935570.1|898124_898865_+|acyl-ACP-thioesterase
MGLTYQEEFTIPFDMVDVKQEIKLPDFISYCLGVSGRQSEELGRSDLYVFQEFGLIWVVTDYELTIQRLPKYNETITIKTEAVAYNKFFCHRMFYIYDAAGNLLLDILCYFVLIDFETRKVAPVPEDLIAPYQSEQVKKLPRAPKYQLLENPSVQEFPVRYFDLDMNGHVNNGKYLEWMYEALGYDFLLCHVPKKIQLKYLKEVEATSLVSSRMVAEAGGSQHEIVVDGHIHAQAVIEWRERHVAG
>NZ_CP002007.2|WP_002935569.1|898851_899469_+|NUDIX-hydrolase
MSQDKWLEWAVRLQALAQTGLAYGKDVYDMERFEEIRQIAAEMLVEPSGQPLEVVKDLFCNETGYQTPKLDTRAAIFQEDKILLVQENDGLWSLPGGWCDVDQSVKDNVVKEVKEEAGLDVEAQRVVAILDKHKNNPAKSAHRVTKVFILCRLLGGEFQPNSETVASGFFSLDDLPPLYLGKNTAEQLALCLEASRSEHWETRFD

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NZ_CP002007_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NZ_CP002007_2

1106963-1107046

Orphan

Consensus_repeat	Method
AACTTCGTTCGCTCTATTTCCAACCTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NZ_CP002007_2

>merge|NZ_CP002007|2|1106963-1107046|CRISPRCasFinder
AACTTCGTTCGCTCTATTTCCAACCTCCCAAGTTTCCCCAAACCTTTGTAGAAATGAACTTCGTTCGCTCAATTTCCAACCTCC

>NZ_CP002007|2|2|1106963-1107046|CRISPRCasFinder
AACTTCGTTCGCTCTATTTCCAACCTCC	CAAGTTTCCCCAAACCTTTGTAGAAATG
AACTTCGTTCGCTCAATTTCCAACCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NZ_CP002007.2\|WP_002935231.1\|1111159_1112191_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271189
NZ_CP002007.2\|WP_009909911.1\|1115540_1116473_+\|tagatose-6-phosphate-kinase	unknown	unknown	gnl\|CDD\|237405
NZ_CP002007.2\|WP_032497578.1\|1100357_1101185_+\|NAD-kinase	unknown	unknown	gnl\|CDD\|235317
NZ_CP002007.2\|WP_002935240.1\|1101184_1102078_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NZ_CP002007.2\|WP_002935242.1\|1099711_1100383_+\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232
NZ_CP002007.2\|WP_029694144.1\|1106519_1106912_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|224961
NZ_CP002007.2\|WP_002935232.1\|1110391_1110934_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP002007.2\|WP_002935247.1\|1096810_1097926_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NZ_CP002007.2\|WP_009909926.1\|1097936_1098914_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|235039
NZ_CP002007.2\|WP_002935234.1\|1108969_1109770_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NZ_CP002007.2\|WP_002935239.1\|1102095_1103070_+\|phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236609
NZ_CP002007.2\|WP_002935248.1\|1096464_1096809_-\|DUF1831-domain-containing-protein	unknown	unknown	gnl\|CDD\|370163
NZ_CP002007.2\|WP_002935243.1\|1099058_1099625_-\|CYTH-domain-containing-protein	unknown	unknown	gnl\|CDD\|143627
NZ_CP002007.2\|WP_002935226.1\|1113593_1114361_+\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268
NZ_CP002007.2\|WP_013730386.1\|1107146_1108307_+\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
NZ_CP002007.2\|WP_002935237.1\|1104793_1106536_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NZ_CP002007.2\|WP_002935233.1\|1109901_1110372_+\|hypothetical-protein	unknown	unknown	unknown
NZ_CP002007.2\|WP_009909915.1\|1112559_1113315_-\|hypothetical-protein	unknown	unknown	unknown
NZ_CP002007.2\|WP_002935225.1\|1114566_1114989_+\|galactose-6-phosphate-isomerase-subunit-LacA	unknown	unknown	gnl\|CDD\|181505
NZ_CP002007.2\|WP_002935224.1\|1115015_1115531_+\|galactose-6-phosphate-isomerase-subunit-LacB	unknown	unknown	gnl\|CDD\|181506

Protein	Function_ID	Function_description	E-value
NZ_CP002007.2\|WP_002935231.1\|1111159_1112191_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.90416e-22
NZ_CP002007.2\|WP_009909911.1\|1115540_1116473_+\|tagatose-6-phosphate-kinase	gnl\|CDD\|237405	PRK13508, PRK13508, tagatose-6-phosphate kinase; Provisional.	1.63555e-171
NZ_CP002007.2\|WP_032497578.1\|1100357_1101185_+\|NAD-kinase	gnl\|CDD\|235317	PRK04885, ppnK, inorganic polyphosphate/ATP-NAD kinase; Provisional.	1.85355e-172
NZ_CP002007.2\|WP_002935240.1\|1101184_1102078_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	7.61445e-90
NZ_CP002007.2\|WP_002935242.1\|1099711_1100383_+\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	5.5421e-94
NZ_CP002007.2\|WP_029694144.1\|1106519_1106912_+\|PaaI-family-thioesterase	gnl\|CDD\|224961	COG2050, PaaI, HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis, transport, and catabolism].	5.94332e-25
NZ_CP002007.2\|WP_002935247.1\|1096810_1097926_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	3.30339e-174
NZ_CP002007.2\|WP_009909926.1\|1097936_1098914_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|235039	PRK02458, PRK02458, ribose-phosphate pyrophosphokinase; Provisional.	0
NZ_CP002007.2\|WP_002935234.1\|1108969_1109770_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	2.87242e-15
NZ_CP002007.2\|WP_002935239.1\|1102095_1103070_+\|phosphate-acetyltransferase	gnl\|CDD\|236609	PRK09653, eutD, phosphotransacetylase.	0
NZ_CP002007.2\|WP_002935248.1\|1096464_1096809_-\|DUF1831-domain-containing-protein	gnl\|CDD\|370163	pfam08866, DUF1831, Putative amino acid metabolism. Solution of the structure of the Lactobacillus plantarum protein from this family has indicated a potential new fold with remote similarities to TBP-like (TATA-binding protein) structures. This similarity, in combination with genomic context analysis, leads us to propose an involvement in amino-acid metabolism. The potentially novel fold is an alpha + beta fold comprising two beta sheets packed against a single helix. The enzyme is present in the cytosol.	1.48439e-52
NZ_CP002007.2\|WP_002935243.1\|1099058_1099625_-\|CYTH-domain-containing-protein	gnl\|CDD\|143627	cd07762, CYTH-like_Pase_1, Uncharacterized subgroup 1 of the CYTH-like superfamily. Enzymes belonging to the CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) superfamily hydrolyze triphosphate-containing substrates, require metal cations as cofactors, and have a unique active site located at the center of an eight-stranded antiparallel beta barrel tunnel (the triphosphate tunnel). The name CYTH originated from the gene designation for bacterial class IV adenylyl cyclases (CyaB) and from thiamine triphosphatase. Class IV adenylate cyclases catalyze the conversion of ATP to 3',5'-cyclic AMP (cAMP) and PPi. Thiamine triphosphatase is a soluble cytosolic enzyme which converts thiamine triphosphate to thiamine diphosphate. This domain superfamily also contains RNA triphosphatases, membrane-associated polyphosphate polymerases, tripolyphosphatases, nucleoside triphosphatases, nucleoside tetraphosphatases and other proteins with unknown functions. Proteins of this subgroup are of bacterial origin and have not been characterized.	3.30094e-69
NZ_CP002007.2\|WP_002935226.1\|1113593_1114361_+\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	2.73173e-82
NZ_CP002007.2\|WP_013730386.1\|1107146_1108307_+\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	1.46415e-147
NZ_CP002007.2\|WP_002935237.1\|1104793_1106536_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.43285e-169
NZ_CP002007.2\|WP_002935225.1\|1114566_1114989_+\|galactose-6-phosphate-isomerase-subunit-LacA	gnl\|CDD\|181505	PRK08621, PRK08621, galactose-6-phosphate isomerase subunit LacA; Reviewed.	6.97048e-84
NZ_CP002007.2\|WP_002935224.1\|1115015_1115531_+\|galactose-6-phosphate-isomerase-subunit-LacB	gnl\|CDD\|181506	PRK08622, PRK08622, galactose-6-phosphate isomerase subunit LacB; Reviewed.	8.87204e-126

>NZ_CP002007.2|WP_029694144.1|1106519_1106912_+|PaaI-family-thioesterase
MKVLDKLNLQPITVLDDYQATMLNEKEVLLTTKVTEKSLNPYGMAHGGFLFTLADSVAGLTTVAGGSYSVTLQSNIHYMKAAKLGDTLSVTGSCTHDGSRTKVVEVKIKNQDKQLLASASFTMFVTGKVE
>NZ_CP002007.2|WP_002935237.1|1104793_1106536_+|ABC-transporter-ATP-binding-protein
MKQSSFKELVRLVLGQPFQMYLMLVGTLVQVLLTVYLPILIGQAVDAVLIADGQVLLGIIGKMVMVILLNTLVQWYLPLVTNRLVYGMVADLREQVYVKLHQMPLSYLDRHSVGDLVARFSSDSEQLTNGLLMVFNQFFIGILTIFLTIFTMARLDLTMMLLVVALTPVSLLVARYIAKKSYGYYRKQTQARGKQSQLLEESISQLTLVQSFNAQEQFTQGFQVVNDQYATYSQQAIFASSTVNPSTRFINAIIYALLAGLGALRIMAGQFTVGSLTTFLNYASQYSKPFNDISSVLSELQSALACADRLFAILALDSIDDQAERKIDSEELKGAISFDNVSFSYSPERSLIEHLDIDVEAGQKVAIVGPTGAGKSTMINLLMRFYDVTAGQIVLDGVPIRQYSREDLRRQIGMVLQETWIKSGTIHDNIAYGYPNATRELVIEAAKAANADFFIRQLPQGYDTVLADGGEGLSQGQRQLLSIARVFVKIPKILILDEATSSIDTRTEILVQEAFAKLMEGRTSFIIAHRLSTIQSADLILVMVDGKIVEQGNHEALMAEQGVYYQMQTSQQTEEDESVR
>NZ_CP002007.2|WP_002935239.1|1102095_1103070_+|phosphate-acetyltransferase
MKIFEQLATKLEGKKVRIVLPEGEEPRILQATKRLVNESDVVPVLLGNPDRIKIYLDIEGITEGFEIIDPAHYDRYDEMVAALVERRKGKVSEEQAHELLKDVNYFGVMLVYMGVVEGMVSGAIHSTASTVRPALQIIKTEPGVSKTSGAFLMVKGEERYIFGDCAINIDPDAQTLAEIAINSARTAKMFGIDPKVAMLSYSTKGSGAGPKVDKVVEATKIAQKLRPELDLDGELQFDAAFVPTTGKLKAPGSSVAGQATVFIFPGISAGNIGYKIAERMGGFAAVGPVLQGLNQPVNDLSRGCNPDDVYNLTLITAVQALEHR
>NZ_CP002007.2|WP_002935240.1|1101184_1102078_+|RluA-family-pseudouridine-synthase
MRFEFIADQHTKIKTFLKKHGVSKGLLAKIKYTGGNIWVNDIEQNATYLLDIGDRVTIDIPAEEDLTGSLKPIFFPLDIVYEDDHFLSINKPVGYASIPSALHSSTIANFVKGYLIEQNYENKQVHIVTRLDRDTSGVMLFAKHGYAHARLDKQLQAKLIHKRYYALVKGNGQLEETGDIIAPIGRPEDSIITRCVTKNGKYAHTSYRVVQSWGDIHLVDIQLHTGRTHQIRVHFSHIGFPLLGDDMYGGSLECGIERQALHCHNLAFDNPFSAERIDLEAPLPEDFQAVINQLISK
>NZ_CP002007.2|WP_032497578.1|1100357_1101185_+|NAD-kinase
MIQMKNTGRKKIALLASRNPKSEAVSKELWTKLKEANFILTPKNPDIVISIGGDGMLLSAFHKYEKLIDRVRFVGIHTGHLGFYTDYRDFEVDKLIENLKLDTGARVSYPILNVKVKMTDGRIVEARALNEATVKRLSKTMVADIIINNVPFERFRGDGISVSTPTGSTAYNKSLGGAVLHPTIEALQIAEVASLNNRVYRTLGSSVVVPKKDKIVIEPKHSDRYSIAVDNKTFVYDSIESIEYQIDNSKIHFVATPSHTSFWNRVKDAFIGEVE
>NZ_CP002007.2|WP_002935242.1|1099711_1100383_+|GTP-pyrophosphokinase-family-protein
MDFNWEEFLDPYIQTVGELKIKLRGIRKQYRKANRHSPIEFVTGRVKPIESIKEKMALRHIKLENLAQDMQDIAGLRIMVQFVDDIEEVLAILRKRKDMQIVHERDYINNMKASGYRSYHVVIEYPVDTINGNETVLAEIQIRTLSMNFWATIEHSLNYKYKGNFPEEIKKRLEVTAKIAYELDEEMRKIRNDIQEAQALFDPAYRKLNDGVGNSDDTDEEYR
>NZ_CP002007.2|WP_002935243.1|1099058_1099625_-|CYTH-domain-containing-protein
MKNHLEIEYKTLLTKSEYKRLLTDFSDVSPILQTNHYIDTPDLDMKNHRFSLRIRTFEDSAELTLKIPQEVGNQEYNQVLDIQTAHDLLENFQLPAGQISDIISATEIPLDKLAVWGILTTKRYEKQTSIGLMALDENDYVGQKDYELEVEVTDADAGKILFDEFLKKKSIQFKYASSKVARTAAHMK
>NZ_CP002007.2|WP_009909926.1|1097936_1098914_-|ribose-phosphate-diphosphokinase
MVQPLGEHNIKLFSLNSNRDIAEKIADSAGIPLGKLSSRQFSDGEIQINIEESVRGVDVYIIQSTSYPVNNHLWELLIMIDACKRASANTITAVIPYFGYARQDRTASPREPITAKLVANMLVKAGVDRVLTLDLHASQIQGFFDIPVDNLLTEPLFAAYYMEKGLCGEDVVIVSPKNSGIKRARNIAEFLNAPIAIIDYAQDDSERSEGYIIGDVAGKKAILVDDILNTGRTFSQASKIVQEGGATEIYAVASHGLFAGTATQLLDEAPIKEILVTDSVASKEQHPKNIVFLTASDLIADAIHRIQEHQPLSPLFKFTSPEKEN
>NZ_CP002007.2|WP_002935247.1|1096810_1097926_-|cysteine-desulfurase
MIYLDNAATTALSPTALQRMMEVAQENYGNPSSIHQSGRKANQRLRQSRQEIAQILSASPEQIIFTSGGSEADTLAIQGYALAHQSKGKHLITTAIEHHAVLHTMQYLEERFGFEVTYIQPVDQVITAQQIQDALRPDTILVSVMFANNETGQLLPIKEIGELLADHQAVFHVDAVQAIGKIAISPSNYGIDLLAASAHKFHGPKGTGFLYSKVHKFDSLIHGGKQEQQHRAGTENLPAIAAMATALTEQYESLDTHHQHVSELRQHIIEGLSGLDYYLNQAGPHLPHVLNIGFPGKLNEQLLMQLDLAGIAVSSGSACTAGVVQNSHVLEAMYGKDSHRLKESIRISLSEINTKEEIDTLIIELKKILGG
>NZ_CP002007.2|WP_002935248.1|1096464_1096809_-|DUF1831-domain-containing-protein
MAFQQSVTLKDCNFTYHISPAIKKYTLRDNTFEQTKAGHYQLTRLLEEIPNSNQGFLLKIIINQDLTGFKINITDKSGLHLVNIFKPESNKVIQEKFYFLMDSLIDRDIFTKES
>NZ_CP002007.2|WP_013730386.1|1107146_1108307_+|A/G-specific-adenine-glycosylase
MLDLKEYGIEMWPEEKIQAFRKALLDWYDANKRDLPWRRTKDPYAIWVSEIMLQQTRVDTVIPYYERFLHYLPTISDLAQAPEEVILKLWEGLGYYSRVRNMQKAAQQMVEDFDGQFPTTHAAISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLSRLFEVDYDIGLPANRKIFQAMMELLIDPERPGDFNQALMDLGSDIESPVNPRPQDSPVKAFSAAYLNGTMDKYPIKAPKKKPIPVAYQGFLIRNKDNQFLLEKNNEAGLLSGFWSFPLLEKGAIVEKQVSLFEVAEEVVQPDIRQSFTELYGLTVDWQEQEFGIVQHIFSHRKWQIEMVEGVAETLNLPESKELKWVSVEDFPTYPFAKPQQKMWENFIKEKEKQKS
>NZ_CP002007.2|WP_002935234.1|1108969_1109770_-|helix-turn-helix-transcriptional-regulator
MILGDILKEYRSKNKLSMDKFAELSGLTKGYISMLEKNQHPKTKKALLPTMDTLEKVAKGMAISVGELIEQLDSNQDIALTITPSQFKLFQQPIHPEVQTLDNELKGDFHAQWLTFGQEQLAAMQTTSITPSASILHLDDYRERIDLPVPGKVSAGTGYWQDTDMNNLVSFYNDEIPDNQSYDTIAQVVGDSMAPHIEDGDYLFIRLTPHIPLNTIGIFSVNGENFVKKFKGDYLQSLNSDYDDIYFSPEDDIRPIGQVVDIYSPD
>NZ_CP002007.2|WP_002935233.1|1109901_1110372_+|hypothetical-protein
MKRMTEISWNDIYKEWETYANHFGLTTPINTENLRDQKSKDFGKGSLITLDLLADYDTDSEKTAAIWVASFCRDLIQDYAYLLNGRAYLTVNQIYFQALKQFQSGAVIWSKPLTRLQPKLFVSYRLLENLDLSHYSCVVELAMLQASMVRTQILEK
>NZ_CP002007.2|WP_002935232.1|1110391_1110934_+|hypothetical-protein
MFNLLNKKAEVSKVAEYWNDTLIERGILSADELLEGKCWRCKSSHGVAVCQIVSSKWSKDASLANQMVLCLSCQHEKPNVADTEIVWQWLEVENDERYWTLQGMAEYEKMYKKSVLQELWDMGIRDGEEVETLVNKVTSLSRKNDIVLNRATLAGLFRCEIEQMRRKAFLNWTGIFKLVS
>NZ_CP002007.2|WP_002935231.1|1111159_1112191_-|tyrosine-type-recombinase/integrase
MATITKRGNSYRATVSLYKKGEYKRETKTFSNRKDAELWTLEMELEKGRGKNIAERSTLFPDFYRNWVHTVKKTDVREATFINYKRTLVIVDDLFDGIQLKHLDDLVMQKKIDQYAETHSKKTVKELVLKIRGSLKYAYARGLISNDFGHLLKSKGQEQPKSITEFKKLRQYCLSHTENEFNVLVALALETVARRGELLGIKKEDIFEYGIKILRSISPTNDDTRLKTKYSKRDISINEDVYQAVTKLAQTKEGYIFDWNGFKQASQLQKLLKQLGLTKTTFHGLRDTHASFLFSKDISLDYISRHLGHNSILTTQQYYLELMPEKKHQQDADALSLLNDLSL
>NZ_CP002007.2|WP_009909915.1|1112559_1113315_-|hypothetical-protein
MALGNVEKDTEGWIELINQYLQYCIEIGLSPYTQATYKVALTKVLGVSSTNFIATQPRTRANRMNNRVLHKDYRLSNKNNDYWHKVVTSTGLRKSELIHVTGDALQRGRDGRWYLNLAGHKHHTKGRRDRWSPIMATSQEEEEWLVAIFQRAGEKKVFHVPKDLILDDFDGKKVPTALKSHKYPTEYAERVYRSVAREISKIRNRKEVIHLRKELVGISLNRKACKIVIKTLGHNRPEEFPRSYAYILLKR
>NZ_CP002007.2|WP_002935226.1|1113593_1114361_+|DeoR/GlpR-transcriptional-regulator
MNKRERLEEITRLVNKKGTVRISEIVELLNVTDMTVRRDFIELEEQGVLTKIHGGARSNKAFQYREYSHSEKHIQNKEAKQEIAERAAQLIEDGDTVFLGPGTTVAFLAEAIKNSRLTVITNCMPVFTILSQKKTEEFQVFLLGGEYRQVTESFVGEITNTSLEKMRFSKIFFSGNGLKGTDVMTSTLAEAYTQNIAIKHSLEKYLLLDASKIGKDDFTSFCDLHDVTALVTDMNAKDENYQLLSKHIEIITTKL
>NZ_CP002007.2|WP_002935225.1|1114566_1114989_+|galactose-6-phosphate-isomerase-subunit-LacA
MTIIIGADPAGSKLKDVIKDYLLEKSYDFKDVSDGSDFVDTTLAVVAEVNQQEGNLGIVIDAYGVGPFMTATKVKGMIAAEVSDERSAYMTRGHNNSRIITIGSEIVGEGIAKNIVKGFVEGEYDGGRHQIRVDMLNKMC
>NZ_CP002007.2|WP_002935224.1|1115015_1115531_+|galactose-6-phosphate-isomerase-subunit-LacB
MKIAIGCDHIVTYEKIAVVDYLKNQGYEVLDFGTYDNVRTHYPIFGKKVGEAVASGQADLGICICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNANVIGFGGKITGELLMCDIIEAFIKAEYKPTEANKRLIEKIAAVETLNQEQANPEFFTEFLEKWDRGEYQD
>NZ_CP002007.2|WP_009909911.1|1115540_1116473_+|tagatose-6-phosphate-kinase
MILTITLNPSVDIAYQLDTFHLDTVNRVEKVQKTAGGKGLNVTRVLKQIGEDVVATGFIGGEIGSYVKKQLTRNDIKNSFVEIGSETRNCIAVLHDGKQTEILEQGPTIQEHEALNFIEHLEIILNNVDVVVISGSLPKGLASNYYVEIVELCKKCGVAVVLDCSGEALKNVLESQQKPTVIKPNTEELSQLIGKEVTDDIQELKSVLSGQLFQGIDWIVVSLGAQGAFAKYKDKFYRVRIPKIKVVNPVGSGDSTVAGIAAGLVHALPEAELLKNANVLGMLNAQEEQTGYVNLVHSESLYSQIEVEEV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NZ_CP002007_1	1.1\|888817\|29\|NZ_CP002007\|CRISPRCasFinder,CRT	888817-888845	29	NZ_CP002007.2	1288751-1288779	0	1.0

1. spacer 1.1|888817|29|NZ_CP002007|CRISPRCasFinder,CRT matches to position: 1288751-1288779, mismatch: 0, identity: 1.0

tggccaaacgtgggatcaaaaccatgttg	CRISPR spacer
tggccaaacgtgggatcaaaaccatgttg	Protospacer
*****************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NZ_CP002007_1	1.5\|889079\|30\|NZ_CP002007\|CRISPRCasFinder,CRT,PILER-CR	889079-889108	30	MK448982	Streptococcus phage Javan554, complete genome	21889-21918	0	1.0
NZ_CP002007_1	1.1\|888817\|29\|NZ_CP002007\|CRISPRCasFinder,CRT	888817-888845	29	NZ_CP012032	Leptospira borgpetersenii serovar Ballum strain 56604 plasmid lbp2, complete sequence	6830-6858	6	0.793
NZ_CP002007_1	1.2\|888882\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888882-888911	30	MK448365	Streptococcus satellite phage Javan212, complete genome	12488-12517	6	0.8
NZ_CP002007_1	1.2\|888882\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888882-888911	30	NZ_CP026119	Halobacillus litoralis strain ERB 031 plasmid pLDW-31, complete sequence	127386-127415	6	0.8
NZ_CP002007_2	2.1\|1106991\|28\|NZ_CP002007\|CRISPRCasFinder	1106991-1107018	28	NZ_CP043555	Vibrio cholerae strain RFB16 plasmid unnamed, complete sequence	6368-6395	6	0.786
NZ_CP002007_1	1.2\|888882\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888882-888911	30	AP019559	Escherichia phage SP15 DNA, complete genome	91136-91165	7	0.767
NZ_CP002007_1	1.2\|888882\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888882-888911	30	NZ_CP014221	Clostridium botulinum strain B515 plasmid pRSJ21_2, complete sequence	10259-10288	7	0.767
NZ_CP002007_1	1.2\|888882\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888882-888911	30	NZ_CP013852	Clostridium botulinum strain B305 plasmid pRSJ6_2, complete sequence	8743-8772	7	0.767
NZ_CP002007_1	1.2\|888882\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888882-888911	30	NZ_CP014172	Clostridium botulinum strain B609 plasmid pRSJ22_1, complete sequence	744-773	7	0.767
NZ_CP002007_1	1.5\|889079\|30\|NZ_CP002007\|CRISPRCasFinder,CRT,PILER-CR	889079-889108	30	NZ_CP013208	Paenibacillus sp. IHB B 3084 plasmid pHD05, complete sequence	11448-11477	7	0.767
NZ_CP002007_1	1.5\|889079\|30\|NZ_CP002007\|CRISPRCasFinder,CRT,PILER-CR	889079-889108	30	NZ_MG205643	Paeniclostridium sordellii strain S0804018 plasmid pCS1-5, complete sequence	56962-56991	7	0.767
NZ_CP002007_1	1.7\|889211\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	889211-889240	30	AJ609634	Bacteriophage EJ-1 proviral DNA, complete genome	6909-6938	7	0.767
NZ_CP002007_1	1.7\|889211\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	889211-889240	30	NC_005294	Streptococcus prophage EJ-1, complete genome	6909-6938	7	0.767
NZ_CP002007_1	1.7\|889211\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	889211-889240	30	KY065449	Streptococcus phage IPP5, complete genome	7026-7055	7	0.767
NZ_CP002007_2	2.1\|1106991\|28\|NZ_CP002007\|CRISPRCasFinder	1106991-1107018	28	NZ_CP040462	Enterococcus sp. M190262 plasmid pM190262, complete sequence	148656-148683	7	0.75
NZ_CP002007_1	1.2\|888882\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888882-888911	30	MT679222	Proteus phage 2, complete genome	96921-96950	8	0.733
NZ_CP002007_1	1.2\|888882\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888882-888911	30	MT679223	Proteus phage 1, complete genome	97178-97207	8	0.733
NZ_CP002007_1	1.2\|888882\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888882-888911	30	NZ_CP053952	Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence	451906-451935	8	0.733
NZ_CP002007_1	1.2\|888882\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888882-888911	30	NZ_CP053949	Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence	101964-101993	8	0.733
NZ_CP002007_1	1.3\|888948\|30\|NZ_CP002007\|CRISPRCasFinder,CRT	888948-888977	30	NZ_CP011666	Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence	115042-115071	9	0.7

1. spacer 1.5|889079|30|NZ_CP002007|CRISPRCasFinder,CRT,PILER-CR matches to MK448982 (Streptococcus phage Javan554, complete genome) position: , mismatch: 0, identity: 1.0

aacatcaatgtatttcttttcgaccttgtc	CRISPR spacer
aacatcaatgtatttcttttcgaccttgtc	Protospacer
******************************

2. spacer 1.1|888817|29|NZ_CP002007|CRISPRCasFinder,CRT matches to NZ_CP012032 (Leptospira borgpetersenii serovar Ballum strain 56604 plasmid lbp2, complete sequence) position: , mismatch: 6, identity: 0.793

tggccaaacgtgggatcaaaaccatgttg	CRISPR spacer
tggccaaacgtgggaaaaaaaccgatttt	Protospacer
***************  ******.  **

3. spacer 1.2|888882|30|NZ_CP002007|CRISPRCasFinder,CRT matches to MK448365 (Streptococcus satellite phage Javan212, complete genome) position: , mismatch: 6, identity: 0.8

ctaagataaataatatcccaattaatactg	CRISPR spacer
aagagataaatactattccaattaatacta	Protospacer
  .********* ***.************.

4. spacer 1.2|888882|30|NZ_CP002007|CRISPRCasFinder,CRT matches to NZ_CP026119 (Halobacillus litoralis strain ERB 031 plasmid pLDW-31, complete sequence) position: , mismatch: 6, identity: 0.8

ctaagataaataatatcccaattaatactg	CRISPR spacer
gaacaataaataataacccaattaatactc	Protospacer
  * .********** *************

5. spacer 2.1|1106991|28|NZ_CP002007|CRISPRCasFinder matches to NZ_CP043555 (Vibrio cholerae strain RFB16 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.786

caagtttccccaaacctttgtagaaatg	CRISPR spacer
ataccttccccaaaactttgtagaaatt	Protospacer
  * .********* ************

6. spacer 1.2|888882|30|NZ_CP002007|CRISPRCasFinder,CRT matches to AP019559 (Escherichia phage SP15 DNA, complete genome) position: , mismatch: 7, identity: 0.767

ctaagataaataatatcccaattaatactg	CRISPR spacer
ttgttctaaataatatcccattaaatactg	Protospacer
.*.   ************** * *******

7. spacer 1.2|888882|30|NZ_CP002007|CRISPRCasFinder,CRT matches to NZ_CP014221 (Clostridium botulinum strain B515 plasmid pRSJ21_2, complete sequence) position: , mismatch: 7, identity: 0.767

ctaagataaataatatcccaattaatactg	CRISPR spacer
ataagaaaaatactatcccaattagtctta	Protospacer
 ***** ***** ***********.* .*.

8. spacer 1.2|888882|30|NZ_CP002007|CRISPRCasFinder,CRT matches to NZ_CP013852 (Clostridium botulinum strain B305 plasmid pRSJ6_2, complete sequence) position: , mismatch: 7, identity: 0.767

ctaagataaataatatcccaattaatactg	CRISPR spacer
ataagaaaaatactatcccaattagtctta	Protospacer
 ***** ***** ***********.* .*.

9. spacer 1.2|888882|30|NZ_CP002007|CRISPRCasFinder,CRT matches to NZ_CP014172 (Clostridium botulinum strain B609 plasmid pRSJ22_1, complete sequence) position: , mismatch: 7, identity: 0.767

ctaagataaataatatcccaattaatactg	CRISPR spacer
ataagaaaaatactatcccaattagtctta	Protospacer
 ***** ***** ***********.* .*.

10. spacer 1.5|889079|30|NZ_CP002007|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013208 (Paenibacillus sp. IHB B 3084 plasmid pHD05, complete sequence) position: , mismatch: 7, identity: 0.767

aacatcaatgtatttcttttcgaccttgtc	CRISPR spacer
tgcatcaatggatttcttttcgtcctgctt	Protospacer
 .******** *********** ***  *.

11. spacer 1.5|889079|30|NZ_CP002007|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MG205643 (Paeniclostridium sordellii strain S0804018 plasmid pCS1-5, complete sequence) position: , mismatch: 7, identity: 0.767

aacatcaatgtatttcttttcgaccttgtc	CRISPR spacer
gacatcaatgtctttcttttcgggtgtatc	Protospacer
.********** **********. . *.**

12. spacer 1.7|889211|30|NZ_CP002007|CRISPRCasFinder,CRT matches to AJ609634 (Bacteriophage EJ-1 proviral DNA, complete genome) position: , mismatch: 7, identity: 0.767

cttctggtagttatccccataacatttgta	CRISPR spacer
gtttctttagttatccccttaacattttta	Protospacer
 **..  *********** ******** **

13. spacer 1.7|889211|30|NZ_CP002007|CRISPRCasFinder,CRT matches to NC_005294 (Streptococcus prophage EJ-1, complete genome) position: , mismatch: 7, identity: 0.767

cttctggtagttatccccataacatttgta	CRISPR spacer
gtttctttagttatccccttaacattttta	Protospacer
 **..  *********** ******** **

14. spacer 1.7|889211|30|NZ_CP002007|CRISPRCasFinder,CRT matches to KY065449 (Streptococcus phage IPP5, complete genome) position: , mismatch: 7, identity: 0.767

cttctggtagttatccccataacatttgta	CRISPR spacer
gtttctttagttatccccttaacattttta	Protospacer
 **..  *********** ******** **

15. spacer 2.1|1106991|28|NZ_CP002007|CRISPRCasFinder matches to NZ_CP040462 (Enterococcus sp. M190262 plasmid pM190262, complete sequence) position: , mismatch: 7, identity: 0.75

caagtttccccaaacctttgtagaaatg	CRISPR spacer
atttgttccgcaaaccgttgtagaaatg	Protospacer
     **** ****** ***********

16. spacer 1.2|888882|30|NZ_CP002007|CRISPRCasFinder,CRT matches to MT679222 (Proteus phage 2, complete genome) position: , mismatch: 8, identity: 0.733

ctaagataaataatatcccaattaatactg	CRISPR spacer
tacggataactaatatcccaactaatacga	Protospacer
.  .***** ***********.****** .

17. spacer 1.2|888882|30|NZ_CP002007|CRISPRCasFinder,CRT matches to MT679223 (Proteus phage 1, complete genome) position: , mismatch: 8, identity: 0.733

ctaagataaataatatcccaattaatactg	CRISPR spacer
tacggataactaatatcccaactaatacga	Protospacer
.  .***** ***********.****** .

18. spacer 1.2|888882|30|NZ_CP002007|CRISPRCasFinder,CRT matches to NZ_CP053952 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagataaataatatcccaattaatactg	CRISPR spacer
tcaagataaaaaatatcccaatcaatctct	Protospacer
..******** ***********.*** ..

19. spacer 1.2|888882|30|NZ_CP002007|CRISPRCasFinder,CRT matches to NZ_CP053949 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

ctaagataaataatatcccaattaatactg	CRISPR spacer
tcaagataaaaaatatcccaatcaatctct	Protospacer
..******** ***********.*** ..

20. spacer 1.3|888948|30|NZ_CP002007|CRISPRCasFinder,CRT matches to NZ_CP011666 (Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence) position: , mismatch: 9, identity: 0.7

taattatctctttggaccgcatcgtggcca	CRISPR spacer
aggtggcgtctttgaaccgcatcgtggccg	Protospacer
 ..* .. ******.**************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

31778 : 41814

Synechococcus_phage(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009908856.1\|31778_35498_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	3.0e-39	27.3
WP_009908857.1\|35500_36955_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	9.4e-58	35.4
WP_009908859.1\|37010_38033_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	3.0e-58	41.1
WP_009908860.1\|38029_38581_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.1e-26	38.5
WP_002935323.1\|38590_40138_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	8.5e-73	47.0
WP_002935322.1\|40202_41033_+	DNA adenine methylase	A0A1S5PRR3	Streptococcus_phage	7.7e-89	59.3
WP_038425698.1\|41022_41814_+	site-specific DNA-methyltransferase	A0A1W6JJW1	Lactococcus_phage	1.8e-26	33.6

DBSCAN-SWA_2

322411 : 393271

Streptococcus_phage(27.27%)

tRNA,transposase,holin,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025310420.1\|322411_323161_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_002937466.1\|323150_323912_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_086558053.1\|324304_325597_-\|transposase	IS110-like element ISSsu7 family transposase	A0A1X9I619	Streptococcus_phage	1.4e-225	100.0
WP_002937462.1\|325990_326557_+	TIGR01440 family protein	NA	NA	NA	NA
WP_002937456.1\|326556_327171_+	DUF1349 domain-containing protein	NA	NA	NA	NA
WP_002937454.1\|327443_327875_+	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_002937449.1\|327954_328956_+	NADP-dependent oxidoreductase	NA	NA	NA	NA
WP_002937445.1\|328981_329827_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_002937439.1\|329819_330689_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_002937437.1\|330681_331893_+	NADH:flavin oxidoreductase/NADH oxidase family protein	NA	NA	NA	NA
WP_002937435.1\|332810_333929_+	pectin acetylesterase	NA	NA	NA	NA
WP_013730135.1\|333938_334958_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_002937432.1\|335179_336463_+	trigger factor	NA	NA	NA	NA
WP_002937351.1\|337507_338428_+	zinc ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002937350.1\|338461_341617_+	pneumococcal-type histidine triad protein	NA	NA	NA	NA
WP_144412078.1\|341697_343063_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.2e-64	52.2
WP_011921912.1\|344148_344730_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_009909339.1\|344921_346526_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	4.4e-141	46.6
WP_024409215.1\|347137_348019_+	fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_001140948.1\|348413_348602_+	50S ribosomal protein L28	NA	NA	NA	NA
WP_004194311.1\|354689_356708_+	ATP-dependent DNA helicase RecG	NA	NA	NA	NA
WP_038425707.1\|356880_358185_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	3.4e-168	72.8
WP_014636805.1\|358249_359209_-	asparaginase	NA	NA	NA	NA
WP_004194297.1\|359278_360124_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_004194296.1\|360125_360644_+	haloacid dehalogenase	A0A0H3UZF4	Geobacillus_virus	8.9e-19	35.5
WP_004194294.1\|360659_361112_-	universal stress protein	NA	NA	NA	NA
WP_002937606.1\|361266_362481_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_009909355.1\|362951_363740_+	GTP-sensing pleiotropic transcriptional regulator CodY	NA	NA	NA	NA
WP_009909357.1\|363741_364293_+	cysteine hydrolase	G3MA16	Bacillus_virus	1.2e-26	38.7
WP_011921928.1\|366321_366669_+	50S ribosomal protein L19	NA	NA	NA	NA
WP_013730145.1\|366850_367525_+	hydrolase	NA	NA	NA	NA
WP_002939046.1\|367742_368045_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_002939044.1\|368044_369511_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_002939042.1\|369510_370950_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_074390696.1\|371267_371423_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_002939037.1\|371725_372724_-	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	5.0e-10	25.7
WP_009909376.1\|374037_375519_+	UDP-glucose--hexose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_002939032.1\|375593_376502_+	EamA family transporter	NA	NA	NA	NA
WP_009909358.1\|376691_377894_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	4.2e-221	97.5
WP_002935152.1\|378176_378806_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_002935151.1\|379012_379387_+	hypothetical protein	NA	NA	NA	NA
WP_002935150.1\|379570_380098_+	YqeG family HAD IIIA-type phosphatase	NA	NA	NA	NA
WP_011922650.1\|380098_381205_+	ribosome biogenesis GTPase YqeH	NA	NA	NA	NA
WP_024379048.1\|381523_381835_+	ribosome assembly RNA-binding protein YhbY	NA	NA	NA	NA
WP_002935147.1\|381847_382480_+	nicotinate-nucleotide adenylyltransferase	G3MA22	Bacillus_virus	2.0e-20	33.8
WP_002935146.1\|382476_383064_+	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	NA	NA	NA	NA
WP_002935141.1\|383518_384028_+	cysteine hydrolase	NA	NA	NA	NA
WP_002935140.1\|384029_384389_+	ribosome silencing factor	NA	NA	NA	NA
WP_009909388.1\|384845_385592_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_024390442.1\|385592_387374_+	hypothetical protein	NA	NA	NA	NA
WP_002935136.1\|387417_388506_+	nucleotidyltransferase	NA	NA	NA	NA
WP_002935135.1\|388507_388888_+	TipAS antibiotic-recognition domain-containing protein	NA	NA	NA	NA
WP_013730152.1\|388947_390327_+	hypothetical protein	NA	NA	NA	NA
WP_004194216.1\|390346_390757_+	peptide deformylase	A0A2I7QLT9	Vibrio_phage	2.1e-10	34.2
WP_013730153.1\|391171_393271_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	7.4e-120	38.1

DBSCAN-SWA_3

433004 : 468881

Streptococcus_phage(97.62%)

integrase,portal,transposase

attL 433181:433195|attR 441556:441570

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002937018.1\|433004_434405_+	Cof-type HAD-IIB family hydrolase	A0A1V0S9I2	Catovirus	2.3e-24	43.5
433181:433195	attL	NA	NA	NA	NA
WP_002937017.1\|434406_434778_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002937015.1\|434804_435731_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	9.9e-170	100.0
WP_024409220.1\|435960_437118_-\|integrase	site-specific integrase	A0A1X9I5C3	Streptococcus_phage	2.2e-219	100.0
WP_013730164.1\|437314_438046_-	hypothetical protein	A0A1X9I5E4	Streptococcus_phage	3.7e-103	100.0
WP_013730165.1\|438093_438477_-	ImmA/IrrE family metallo-endopeptidase	A0A1X9I5R2	Streptococcus_phage	2.9e-67	100.0
WP_002937004.1\|438483_438864_-	helix-turn-helix transcriptional regulator	A0A1X9I5A1	Streptococcus_phage	3.9e-64	100.0
WP_002937001.1\|439048_439249_+	helix-turn-helix transcriptional regulator	A0A1X9I583	Streptococcus_phage	9.6e-30	100.0
WP_013730167.1\|439717_439972_+	hypothetical protein	A0A1X9I581	Streptococcus_phage	9.7e-43	100.0
WP_013730168.1\|440012_440261_+	hypothetical protein	A0A1X9I6Q0	Streptococcus_phage	1.1e-38	100.0
WP_022540561.1\|440250_440403_+	hypothetical protein	A0A1X9I663	Streptococcus_phage	2.0e-19	100.0
WP_013730169.1\|440407_440749_+	hypothetical protein	A0A1X9I5G6	Streptococcus_phage	2.1e-56	100.0
WP_013730170.1\|440748_441228_+	siphovirus Gp157 family protein	A0A1X9I5D2	Streptococcus_phage	4.8e-67	100.0
WP_013730171.1\|441224_441470_+	hypothetical protein	A0A1X9I5F0	Streptococcus_phage	4.3e-40	100.0
WP_013730172.1\|441450_441915_+	hypothetical protein	A0A1X9I5S7	Streptococcus_phage	7.1e-84	100.0
441556:441570	attR	NA	NA	NA	NA
WP_013730173.1\|441883_443056_+	hypothetical protein	M1PF69	Streptococcus_phage	7.0e-229	98.7
WP_013730175.1\|443405_444104_+	ERF family protein	A0A1X9I5A9	Streptococcus_phage	2.2e-113	100.0
WP_022540564.1\|444103_444400_+	hypothetical protein	A0A1X9I5B1	Streptococcus_phage	1.6e-52	100.0
WP_022540565.1\|444396_444795_+	single-stranded DNA-binding protein	A0A1X9I6R5	Streptococcus_phage	2.7e-68	100.0
WP_013730177.1\|444805_445633_+	bifunctional DNA primase/polymerase	A0A1X9I684	Streptococcus_phage	4.6e-158	100.0
WP_079253058.1\|445616_446996_+	helicase	A0A1X9I5H6	Streptococcus_phage	3.8e-266	99.8
WP_013730179.1\|447352_447508_+	hypothetical protein	A0A1X9I5E8	Streptococcus_phage	9.7e-22	100.0
WP_013730180.1\|447504_447813_+	DUF1372 family protein	A0A1X9I5G5	Streptococcus_phage	3.8e-49	100.0
WP_013730181.1\|447814_448030_+	hypothetical protein	A0A1X9I5W1	Streptococcus_phage	9.7e-36	100.0
WP_013730182.1\|448218_448533_+	hypothetical protein	A0A1X9I5C1	Streptococcus_phage	5.2e-54	100.0
WP_002937915.1\|448605_449040_+	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	2.0e-72	100.0
WP_024409219.1\|449576_449936_+	hypothetical protein	A0A1X9I6S2	Streptococcus_phage	9.8e-41	99.2
WP_013730185.1\|449932_451198_+\|portal	phage portal protein	A0A1X9I693	Streptococcus_phage	5.4e-243	100.0
WP_013730186.1\|451190_452411_+	hypothetical protein	A0A1X9I5H8	Streptococcus_phage	2.0e-239	100.0
WP_022540567.1\|452415_452649_+	hypothetical protein	A0A1X9I5G0	Streptococcus_phage	1.6e-39	100.0
WP_162487885.1\|452850_454143_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	1.3e-212	93.5
WP_009909540.1\|455767_456406_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	4.6e-126	100.0
WP_024409271.1\|456468_458982_+	bifunctional DnaQ family exonuclease/ATP-dependent helicase	A0A1X9I5C8	Streptococcus_phage	0.0e+00	100.0
WP_013730270.1\|459143_460220_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.1e-195	100.0
WP_009909544.1\|460284_461523_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.2e-223	100.0
WP_009909545.1\|461532_462318_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.6e-136	100.0
WP_013730271.1\|462340_462745_-	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	1.1e-64	100.0
WP_013730272.1\|462871_463723_+	DegV family protein	A0A1X9I5J4	Streptococcus_phage	6.3e-155	100.0
WP_025310423.1\|463821_465081_-	PLP-dependent aminotransferase family protein	A0A1X9I5H2	Streptococcus_phage	4.5e-242	99.8
WP_012775019.1\|465202_465937_+	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	1.5e-120	99.5
WP_024409273.1\|466041_467487_+	LCP family protein	A0A1X9I5X1	Streptococcus_phage	1.6e-227	99.8
WP_011922111.1\|467504_468194_+	capsular polysaccharide biosynthesis protein CpsC	A0A1X9I5E1	Streptococcus_phage	1.3e-110	96.1
WP_009909562.1\|468203_468881_+	tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	1.6e-121	100.0

DBSCAN-SWA_4

547464 : 605583

Streptococcus_phage(78.26%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009909666.1\|547464_549702_+	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	1.4e-97	94.0
WP_002935351.1\|549703_549847_+\|transposase	transposase	NA	NA	NA	NA
WP_002935353.1\|550025_550682_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	2.1e-113	99.1
WP_002935354.1\|550775_551603_+	hypothetical protein	M1PFV6	Streptococcus_phage	6.6e-133	97.8
WP_002935355.1\|551608_552880_+	toxic anion resistance protein	M1PLC8	Streptococcus_phage	1.7e-212	100.0
WP_002935357.1\|552916_553783_-	YitT family protein	M1Q1P6	Streptococcus_phage	4.6e-153	99.7
WP_002935358.1\|553957_554596_+	dTMP kinase	M1PSC7	Streptococcus_phage	2.6e-113	98.6
WP_002935359.1\|554592_555477_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.6e-153	98.3
WP_002935361.1\|555496_555814_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	3.1e-54	100.0
WP_002935362.1\|555815_556679_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	2.1e-158	99.7
WP_002935363.1\|557148_558240_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.5e-204	98.6
WP_002935364.1\|558239_558797_+	GNAT family acetyltransferase	M1PSC3	Streptococcus_phage	4.5e-93	98.4
WP_002935365.1\|559170_560352_+	phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	2.7e-220	99.7
WP_002935366.1\|560354_560861_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.2e-92	97.0
WP_002935368.1\|560844_561198_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.9e-60	100.0
WP_009909675.1\|561214_562114_-	cation transporter	M1Q1N9	Streptococcus_phage	1.3e-161	98.3
WP_002935370.1\|562413_563241_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	8.3e-152	99.6
WP_002935371.1\|563396_565058_+	hypothetical protein	NA	NA	NA	NA
WP_002935372.1\|565217_566606_+	amino acid permease	NA	NA	NA	NA
WP_002935373.1\|566728_567610_+	DUF975 family protein	NA	NA	NA	NA
WP_002935375.1\|567802_568639_+	DUF975 family protein	NA	NA	NA	NA
WP_002935376.1\|568656_569532_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002935377.1\|569654_570266_+	DUF3885 domain-containing protein	NA	NA	NA	NA
WP_024409330.1\|570661_571606_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	3.9e-20	33.3
WP_002935380.1\|574274_576197_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_029694137.1\|576473_577352_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_002935387.1\|577676_578423_+	hypothetical protein	NA	NA	NA	NA
WP_002935389.1\|579274_580993_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	0.0e+00	99.0
WP_002935390.1\|581083_581653_-	ECF transporter S component	NA	NA	NA	NA
WP_002935392.1\|581639_582188_-	phosphopantothenoylcysteine decarboxylase	A0A068EHP1	Penguinpox_virus	2.8e-23	37.8
WP_022540619.1\|582180_582876_-	phosphopantothenate--cysteine ligase	NA	NA	NA	NA
WP_002935394.1\|583379_585050_+	formate--tetrahydrofolate ligase	NA	NA	NA	NA
WP_002935395.1\|585093_585903_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_002935400.1\|587677_588529_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_002935402.1\|588686_589304_+	DUF5052 family protein	A0A2K9VCV0	Lactobacillus_phage	3.8e-48	51.5
WP_002935404.1\|589304_589814_+	N-acetyltransferase	NA	NA	NA	NA
WP_002935405.1\|589803_590457_+	DNA alkylation repair protein	NA	NA	NA	NA
WP_002935406.1\|590467_590755_+	DUF1905 domain-containing protein	NA	NA	NA	NA
WP_002935416.1\|591051_591828_-	glycyl-radical enzyme activating protein	NA	NA	NA	NA
WP_002935421.1\|591959_592703_+	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002935426.1\|592715_593690_+	sugar-binding transcriptional regulator	NA	NA	NA	NA
WP_002935429.1\|593876_594200_+	PTS lactose/cellobiose transporter subunit IIA	NA	NA	NA	NA
WP_002935430.1\|594232_594538_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_002935431.1\|594550_595852_+	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002935432.1\|596003_598448_+	glycyl radical protein	A0A2H4YEI2	Aeromonas_phage	4.9e-06	47.2
WP_002935438.1\|598462_599131_+	fructose-6-phosphate aldolase	E3SKN5	Synechococcus_phage	1.5e-21	31.0
WP_002935440.1\|599162_600119_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_002935441.1\|600239_601334_+	glycerol dehydrogenase	NA	NA	NA	NA
WP_002935442.1\|601502_602579_+	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_002935444.1\|602651_603587_+	4-hydroxy-tetrahydrodipicolinate synthase	NA	NA	NA	NA
WP_086558053.1\|604290_605583_+\|transposase	IS110-like element ISSsu7 family transposase	A0A1X9I619	Streptococcus_phage	1.4e-225	100.0

DBSCAN-SWA_5

826722 : 841262

Streptococcus_phage(100.0%)

integrase

attL 829971:829987|attR 839427:839443

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002935718.1\|826722_827850_+	glycerate kinase	W6LM47	Streptococcus_phage	5.7e-87	58.0
WP_002935708.1\|827840_828068_+	hypothetical protein	NA	NA	NA	NA
WP_013730449.1\|828077_828530_-	DUF1694 domain-containing protein	NA	NA	NA	NA
WP_002935704.1\|828679_829987_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	8.3e-247	100.0
829971:829987	attL	NA	NA	NA	NA
WP_024415669.1\|830146_831310_-\|integrase	site-specific integrase	A0A1X9I6A9	Streptococcus_phage	9.7e-223	99.7
WP_024409199.1\|831393_831939_-	helix-turn-helix transcriptional regulator	A0A1X9I5U6	Streptococcus_phage	9.5e-96	100.0
WP_024409200.1\|832096_832285_+	hypothetical protein	A0A1X9I5U7	Streptococcus_phage	7.2e-27	100.0
WP_024409201.1\|832463_832739_+	hypothetical protein	A0A1X9I5W5	Streptococcus_phage	8.0e-43	100.0
WP_024409202.1\|832728_832932_+	hypothetical protein	A0A1X9I5V6	Streptococcus_phage	4.4e-30	100.0
WP_024409203.1\|832924_833128_+	hypothetical protein	A0A1X9I725	Streptococcus_phage	2.8e-29	100.0
WP_024409204.1\|833138_833405_+	hypothetical protein	A0A1X9I6M4	Streptococcus_phage	5.6e-41	100.0
WP_162841287.1\|833415_833574_+	hypothetical protein	A0A1X9I5Z1	Streptococcus_phage	3.1e-23	100.0
WP_024409205.1\|833578_833794_+	hypothetical protein	A0A1X9I5W7	Streptococcus_phage	2.4e-34	100.0
WP_079269917.1\|833807_834602_+	DnaD domain protein	A0A1X9I617	Streptococcus_phage	1.3e-149	100.0
WP_024409207.1\|834617_835463_+	ATP-binding protein	A0A1X9I6C4	Streptococcus_phage	2.6e-156	100.0
WP_024409208.1\|835930_836371_+	hypothetical protein	A0A1X9I5V5	Streptococcus_phage	2.0e-75	100.0
WP_024409209.1\|836440_836941_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.3e-94	100.0
WP_009910450.1\|837080_837467_+	hypothetical protein	A0A1X9I5X3	Streptococcus_phage	4.6e-60	100.0
WP_009910449.1\|837650_837833_+	type II toxin-antitoxin system HicA family toxin	A0A1X9I5W4	Streptococcus_phage	3.7e-28	100.0
WP_009910448.1\|837872_838325_+	type II toxin-antitoxin system HicB family antitoxin	A0A1X9I727	Streptococcus_phage	1.7e-82	100.0
WP_009910447.1\|838436_838646_+	hypothetical protein	A0A1X9I6N3	Streptococcus_phage	1.0e-34	100.0
WP_012775256.1\|839752_839974_+	hypothetical protein	A0A1X9I609	Streptococcus_phage	1.2e-33	100.0
839427:839443	attR	NA	NA	NA	NA
WP_009910443.1\|839975_840236_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5S8E8	Streptococcus_phage	3.9e-23	55.8
WP_002935700.1\|840402_841044_+	HAD family hydrolase	NA	NA	NA	NA
WP_002935693.1\|841076_841262_-	hypothetical protein	W6LMT3	Streptococcus_phage	2.3e-17	68.9

DBSCAN-SWA_6

925764 : 976374

Streptococcus_phage(30.0%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013730428.1\|925764_927021_-\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	7.5e-128	56.4
WP_013730427.1\|927327_929139_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	Q84421	Paramecium_bursaria_Chlorella_virus	9.5e-100	37.6
WP_013730426.1\|929312_929954_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_009909533.1\|929963_930596_+	amino acid ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.6e-32	38.9
WP_024390310.1\|930622_931453_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002935153.1\|932003_933206_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	3.2e-213	93.8
WP_013730423.1\|933585_934731_+	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_013730422.1\|934754_935756_+	tagatose-bisphosphate aldolase	NA	NA	NA	NA
WP_013730421.1\|936496_937456_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013730419.1\|938507_939401_+	ABC transporter permease	NA	NA	NA	NA
WP_002938126.1\|939410_940211_+	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	9.0e-10	23.8
WP_002938125.1\|940414_941482_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_002938123.1\|941494_942364_-	shikimate dehydrogenase	NA	NA	NA	NA
WP_002938121.1\|942409_943435_-	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	3.2e-44	35.2
WP_002938119.1\|943444_944482_-	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	2.2e-45	34.3
WP_002938116.1\|944782_945376_-	DUF1361 domain-containing protein	NA	NA	NA	NA
WP_074390814.1\|945475_947533_+\|tRNA	methionine--tRNA ligase	A0A1V0SEZ7	Hokovirus	5.8e-85	31.1
WP_002938107.1\|947596_948538_+	competence protein CoiA	NA	NA	NA	NA
WP_009910108.1\|948769_950572_+	oligoendopeptidase F	NA	NA	NA	NA
WP_002938105.1\|950573_951014_+	hypothetical protein	NA	NA	NA	NA
WP_002938103.1\|951029_951578_+	hypothetical protein	NA	NA	NA	NA
WP_009910106.1\|951652_952372_+	O-methyltransferase	NA	NA	NA	NA
WP_002938100.1\|952432_953434_+	peptidylprolyl isomerase PrsA	NA	NA	NA	NA
WP_002938099.1\|953698_954184_+	LURP-one-related family protein	NA	NA	NA	NA
WP_009910105.1\|954463_957082_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.5e-61	34.2
WP_002938097.1\|957156_957609_+	cytidine deaminase	NA	NA	NA	NA
WP_002938096.1\|957812_958007_+	hypothetical protein	NA	NA	NA	NA
WP_013730415.1\|958157_958724_+	DUF3267 domain-containing protein	NA	NA	NA	NA
WP_009910096.1\|958736_958952_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013730414.1\|958948_959707_+	DUF3169 family protein	NA	NA	NA	NA
WP_009910094.1\|959728_959935_+	hypothetical protein	NA	NA	NA	NA
WP_012775187.1\|959960_960650_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002936096.1\|960659_960977_+	hypothetical protein	NA	NA	NA	NA
WP_002936095.1\|960986_961661_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002936094.1\|961768_962863_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_002936093.1\|963773_964589_+	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002936092.1\|964640_965282_+	RpiB/LacA/LacB family sugar-phosphate isomerase	NA	NA	NA	NA
WP_002936090.1\|965298_966300_+	sugar kinase	NA	NA	NA	NA
WP_022540650.1\|966310_966952_+	bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	NA	NA	NA	NA
WP_032505201.1\|967237_967672_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002936082.1\|967683_968874_+	glycoside hydrolase family 88 protein	NA	NA	NA	NA
WP_002936080.1\|968883_969375_+	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	NA	NA	NA	NA
WP_002936077.1\|969394_970171_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_002936073.1\|970157_970973_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_009910076.1\|970979_971288_+	preprotein translocase subunit YajC	NA	NA	NA	NA
WP_009910073.1\|971384_974879_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_002935153.1\|975171_976374_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	3.2e-213	93.8

DBSCAN-SWA_7

1166828 : 1177103

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002936496.1\|1166828_1168481_-	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	6.2e-13	24.3
WP_002936495.1\|1168477_1168801_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_009909865.1\|1168919_1169180_+	metal-sensitive transcriptional regulator	NA	NA	NA	NA
WP_009909862.1\|1169190_1169748_+	sugar O-acetyltransferase	A0A191KBJ5	Streptococcus_virus	4.9e-07	38.6
WP_009909860.1\|1169806_1170649_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	4.7e-33	44.3
WP_024409355.1\|1170741_1172835_+	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	3.1e-102	36.5
WP_002936486.1\|1173411_1173906_+	50S ribosomal protein L10	NA	NA	NA	NA
WP_002936483.1\|1173971_1174337_+	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_006738653.1\|1174595_1174769_+	hypothetical protein	NA	NA	NA	NA
WP_009909851.1\|1174765_1175590_+	replication initiator protein A	A0A286QNA4	Streptococcus_phage	5.8e-12	37.6
WP_029743109.1\|1175747_1177103_+	DNA (cytosine-5-)-methyltransferase	A0A141E1L1	Streptococcus_phage	2.9e-125	55.6

DBSCAN-SWA_8

1253485 : 1266924

Streptococcus_phage(71.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038425701.1\|1253485_1254670_+	DNA (cytosine-5-)-methyltransferase	A0A141E1L1	Streptococcus_phage	4.0e-123	58.1
WP_024406079.1\|1254666_1255626_+	DNA cytosine methyltransferase	D2IZY5	Enterococcus_phage	7.3e-75	49.5
WP_050571928.1\|1255703_1256075_+	hypothetical protein	NA	NA	NA	NA
WP_024406080.1\|1256093_1263365_+	DEAD/DEAH box helicase family protein	A0A248SL14	Klebsiella_phage	4.1e-287	37.4
WP_024383732.1\|1263361_1264000_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_024383731.1\|1264046_1264340_-	hypothetical protein	E4ZFJ0	Streptococcus_phage	6.3e-30	64.6
WP_024383730.1\|1264326_1264677_-	hypothetical protein	M1PLN9	Streptococcus_phage	4.3e-25	51.6
WP_024383729.1\|1264673_1266089_-	Y-family DNA polymerase	Q6DMX4	Streptococcus_phage	1.2e-198	71.8
WP_024383728.1\|1266231_1266924_-	helix-turn-helix transcriptional regulator	A0A1B0RXB1	Streptococcus_phage	1.3e-86	72.5

DBSCAN-SWA_9

1385819 : 1457383

Streptococcus_phage(81.82%)

transposase,tRNA,protease,holin,capsid,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013730345.1\|1385819_1387037_-\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_002939269.1\|1387038_1388181_-	cysteine desulfurase	NA	NA	NA	NA
WP_002939268.1\|1388293_1388710_+	hypothetical protein	NA	NA	NA	NA
WP_013730344.1\|1388770_1389154_+	hypothetical protein	NA	NA	NA	NA
WP_024409196.1\|1389172_1390201_-	amino acid lyase	NA	NA	NA	NA
WP_013730343.1\|1390371_1391577_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_012775068.1\|1392179_1392413_-	DUF2969 domain-containing protein	NA	NA	NA	NA
WP_086558053.1\|1392596_1393889_+\|transposase	IS110-like element ISSsu7 family transposase	A0A1X9I619	Streptococcus_phage	1.4e-225	100.0
WP_013730342.1\|1394102_1395125_-	branched-chain amino acid aminotransferase	NA	NA	NA	NA
WP_002935490.1\|1395235_1395853_-	DUF4230 domain-containing protein	NA	NA	NA	NA
WP_009909731.1\|1396024_1398478_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	2.0e-92	32.3
WP_002935488.1\|1398678_1399131_-	hypothetical protein	NA	NA	NA	NA
WP_002935487.1\|1399133_1399628_-	DUF1232 domain-containing protein	NA	NA	NA	NA
WP_002935485.1\|1399660_1400263_-	Fic family protein	NA	NA	NA	NA
WP_002935482.1\|1400286_1402236_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	9.2e-125	42.9
WP_009909724.1\|1402378_1403023_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_002935480.1\|1403032_1406686_-	helicase-exonuclease AddAB subunit AddA	G3MA40	Bacillus_virus	5.5e-22	23.6
WP_002935479.1\|1406685_1409952_-	ATP-dependent nuclease subunit B	NA	NA	NA	NA
WP_002935476.1\|1414004_1414169_-	hypothetical protein	NA	NA	NA	NA
WP_013730339.1\|1414541_1415855_-	GTPase ObgE	NA	NA	NA	NA
WP_002935474.1\|1416058_1416187_-	DUF4044 domain-containing protein	NA	NA	NA	NA
WP_013730338.1\|1416243_1418028_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_009909716.1\|1418267_1419011_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.3e-26	29.4
WP_009909715.1\|1419007_1420618_+	hypothetical protein	NA	NA	NA	NA
WP_013730337.1\|1421185_1421941_-	M15 family metallopeptidase	NA	NA	NA	NA
WP_002935464.1\|1422291_1422543_-\|holin	holin	NA	NA	NA	NA
WP_013730336.1\|1422785_1423550_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_013730335.1\|1423628_1424312_-	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_009909709.1\|1424590_1425331_-	hypothetical protein	NA	NA	NA	NA
WP_009909707.1\|1425772_1428052_-	DNA helicase PcrA	A7KV33	Bacillus_phage	1.2e-128	41.0
WP_002935458.1\|1428341_1429709_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_002935455.1\|1429893_1430232_-	hypothetical protein	NA	NA	NA	NA
WP_002935451.1\|1430398_1432189_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	0.0e+00	100.0
WP_086558053.1\|1432403_1433696_-\|transposase	IS110-like element ISSsu7 family transposase	A0A1X9I619	Streptococcus_phage	1.4e-225	100.0
WP_024394270.1\|1434097_1434475_-	hypothetical protein	A0A1X9I733	Streptococcus_phage	1.9e-63	100.0
WP_024409231.1\|1434539_1435277_-	PlySs2 family phage lysin	A0A1X9I5W6	Streptococcus_phage	1.9e-139	100.0
WP_029743088.1\|1435373_1435760_-\|holin	phage holin family protein	A0A1X9I5Y2	Streptococcus_phage	1.1e-61	100.0
WP_024409233.1\|1435805_1436150_-	hypothetical protein	A0A1X9I5X6	Streptococcus_phage	6.7e-63	100.0
WP_024409234.1\|1436152_1436368_-	hypothetical protein	A0A1X9I729	Streptococcus_phage	4.3e-28	100.0
WP_024409235.1\|1436367_1441674_-	hypothetical protein	A0A1X9I6P1	Streptococcus_phage	0.0e+00	100.0
WP_002937853.1\|1441670_1442366_-	adenylosuccinate synthetase	M1PFK1	Streptococcus_phage	5.8e-130	100.0
WP_002937855.1\|1442365_1444948_-	hypothetical protein	M1NRZ6	Streptococcus_phage	6.2e-262	100.0
WP_024409236.1\|1444937_1445321_-	DUF5361 domain-containing protein	A0A1X9I625	Streptococcus_phage	3.6e-65	100.0
WP_024415622.1\|1445317_1445596_-	hypothetical protein	M1Q1D2	Streptococcus_phage	3.6e-43	100.0
WP_024409238.1\|1445606_1446194_-	hypothetical protein	A0A1X9I5X2	Streptococcus_phage	3.3e-102	100.0
WP_024409239.1\|1446209_1446545_-	hypothetical protein	A0A1X9I5X7	Streptococcus_phage	6.5e-55	100.0
WP_024409240.1\|1446541_1446781_-	hypothetical protein	A0A1X9I5Y4	Streptococcus_phage	4.8e-36	100.0
WP_024409241.1\|1446773_1447112_-	hypothetical protein	A0A1X9I5Z3	Streptococcus_phage	4.7e-61	100.0
WP_024409242.1\|1447098_1447494_-	phage Gp19/Gp15/Gp42 family protein	A0A1X9I730	Streptococcus_phage	3.7e-65	100.0
WP_047020681.1\|1447497_1447710_-	hypothetical protein	A0A1X9I6Q1	Streptococcus_phage	4.3e-28	98.5
WP_024390456.1\|1447716_1448607_-\|capsid	phage major capsid protein	M1PF50	Streptococcus_phage	6.8e-168	100.0
WP_024409244.1\|1448610_1449075_-	DUF4355 domain-containing protein	A0A1X9I604	Streptococcus_phage	5.5e-76	100.0
WP_024409245.1\|1449155_1450571_-\|terminase	terminase	A0A1X9I637	Streptococcus_phage	1.2e-267	100.0
WP_024390459.1\|1450654_1450885_-	hypothetical protein	A0A1X9I6E9	Streptococcus_phage	4.8e-33	100.0
WP_024390460.1\|1450884_1451139_-	hypothetical protein	A0A1X9I5Y1	Streptococcus_phage	1.2e-40	100.0
WP_002938966.1\|1452919_1453258_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	1.9e-54	100.0
WP_013730266.1\|1453267_1454371_-	prephenate dehydrogenase	NA	NA	NA	NA
WP_004194717.1\|1454378_1455545_-	chorismate synthase	A0A291AU41	Pandoravirus	3.5e-39	34.9
WP_004194719.1\|1455548_1456223_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.7e-79	64.6
WP_004194720.1\|1456219_1457383_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	2.1e-140	64.7

DBSCAN-SWA_10

2145685 : 2165032

Streptococcus_phage(66.67%)

integrase,transposase

attL 2150717:2150774|attR 2163489:2163546

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002938187.1\|2145685_2146522_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	1.3e-22	32.9
WP_013730677.1\|2146518_2147058_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_002939074.1\|2147067_2147925_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002939071.1\|2148006_2149290_-	insulinase family protein	NA	NA	NA	NA
WP_009911054.1\|2149286_2150540_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	4.2e-232	99.0
2150717:2150774	attL	NA	NA	NA	NA
WP_013730680.1\|2151323_2151872_-	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	4.7e-50	58.1
WP_013730681.1\|2151949_2152408_-	hypothetical protein	A0A1X9I5V5	Streptococcus_phage	7.6e-22	42.0
WP_013730682.1\|2152420_2153236_-	DnaD domain protein	A0A2I6QQV2	Streptococcus_phage	2.0e-81	66.0
WP_013730683.1\|2153222_2153507_-	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	8.9e-37	83.9
WP_024409270.1\|2153496_2153835_-	hypothetical protein	A0A1X9I5Z6	Streptococcus_phage	5.1e-47	97.8
WP_013730685.1\|2153831_2153981_-	hypothetical protein	A0A1X9I6A8	Streptococcus_phage	2.4e-17	89.8
WP_013730686.1\|2153992_2154196_-	hypothetical protein	A0A1X9I5T6	Streptococcus_phage	7.2e-25	79.1
WP_013730687.1\|2154183_2154573_-	hypothetical protein	NA	NA	NA	NA
WP_013730688.1\|2155011_2155638_-	Rha family transcriptional regulator	A0A192Y918	Salmonella_phage	9.5e-15	32.8
WP_013730689.1\|2155650_2156397_-	Bro-N domain-containing protein	A0A0A7RW33	Clostridium_phage	2.1e-24	50.7
WP_013730690.1\|2156415_2156643_-	helix-turn-helix transcriptional regulator	Q38329	Lactococcus_phage	2.8e-09	51.6
WP_013730691.1\|2156796_2157510_+	helix-turn-helix transcriptional regulator	Q708R9	Streptococcus_phage	3.7e-15	50.6
WP_013730692.1\|2157873_2158704_+	KilA-N domain-containing protein	Q4ZC41	Staphylococcus_virus	1.2e-89	62.1
WP_013730693.1\|2158868_2160041_+\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	3.1e-216	96.9
WP_002936175.1\|2160178_2160562_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	4.6e-36	94.5
WP_002936177.1\|2160564_2161659_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_086558053.1\|2162097_2163390_-\|transposase	IS110-like element ISSsu7 family transposase	A0A1X9I619	Streptococcus_phage	1.4e-225	100.0
WP_014637236.1\|2163550_2165032_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	3.6e-97	41.9
2163489:2163546	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NZ_CP002007

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection