CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_018528	Lactobacillus helveticus R0052, complete sequence	3 crisprs	cas14j,cas3,csa3,cas2,cas5,cas8c,cas7,cas4,cas1,DEDDh,DinG,WYL,cas14k,RT,Cas14u_CAS-V	0	5	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_018528_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018528_1

580774-583071

TypeI

I-C

Consensus_repeat	Method
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	PILER-CR
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CRISPRCasFinder
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CRT

34 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3

The CRISPR arrays of NC_018528_1

>merge|NC_018528|1|580774-583071|PILER-CR,CRISPRCasFinder,CRT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAATAATGACTGATGAACAAAAGACAGCATTGAAGAATGTCGCACTCCTTGTGAGTGCGTGGATTGAAATTGTTCAGCTCTATCTTGATGTCAAAGATCCTAACGGGTCGCACTCCTTGTGAGTGCGTGGATTGAAATATTCTGTAAGGACTGAAACACAAACTCTAAAATATAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATATCGTTATGCAGGTATTACTACTGCTACTAATACGTCGCACTCCTTGTGAGTGCGTGGATTGAAATTCAGGAGATACTGCCGTTGGCTTTGAAGATAAATAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATAATTCATTACTGGCATTACTCCAGTCACTGCGCCAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATGAAAGGAAATATATATGTCAGTCAAAGTTAATGGTGTCGCACTCCTTGTGAGTGCGTGGATTGAAATGATTTTGTTAGAAAATTAACCGATGATTTTTTACAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATTACCCACCTAGCTTAGCACCTACATGGAATGACAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATCATTGTAGTAAAAGTTGCAGGGTCTTGAGTAAGAACGTCGCACTCCTTGTGAGTGCGTGGATTGAAATAATTAAGTCTAATCATAGGGGCAATAATTGCTTAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATTTTTTCGTCTTCTGCTCCTAGTGACTTAGTGAGCCGTCGCACTCCTTGTGAGTGCGTGGATTGAAATAAGTGAATCGACAGGTATTGCAGATGATGATTTAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATAAGATGTGGAAGAGTGCAAGCACACACAGTCCCAAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATTTAGAATACTTATGATCCTTAGATAGATGAACCGGTCGCACTCCTTGTGAGTGCGTGGATTGAAATCTCTGATCTGCTCAGCACGTTGCTCTTGCTTTGAAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATGATTATTCGGAACAACAGATGATCCTAAATGCTCAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATCTAAAGCATACTTAGTAGCATATGAACTGGCTGACGTCGCACTCCTTGTGAGTGCGTGGATTGAAATTACAAACACTTGCCAACTTATAATCCACAAATGCGTCGCACTCCTTGTGAGTGCGTGGATTGAAATAAAGGTGTGTGGATACCTGCTGAATATTGGTTAGGTCGCACTCCTTGTGAGTGCGTGGATTGAAATAGCATCAACGGCTCTAATTATGTCATTGCCGGTTTGTCGCACTCCTTGTGAGTGCGTGGATTGAAATACCTGATCAAACGTTAGGCAATAGATTAACCGAAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATTTTACGAATGTCTTGCCAATTAGTATATTTACTTGTCGCACTCCTTGTGAGTGCGTGGATTGAAATAGAATCAAGACCACCTGTTAGCGTTTTACCACCGGTCGCACTCCTTGTGAGTGCGTGGATTGAAATAAAGAACATAGTTTGCAGAACTGTTTCCAAGTAAAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATGGCTTTAGATGCGTCAAATGCCGCCTGTGGGCTATCGTCGCACTCCTTGTGAGTGCGTGGATTGAAATAGAAGATGGATACAATTTTTAGAAATTCCAGTCTGTCGCACTCCTTGTGAGTGCGTGGATTGAAATACACCATATGTGGTCAACGCTTTAATTGGATTACGGTCGCACTCCTTGTGAGTGCGTGGATTGAAATACTAACTGGAACATCCAAGTACTGTGCGGAAACCGTCGCACTCCTTGTGAGTGCGTGGATTGAAATATCGGCTAATTGCTTTTCAAGTGAATCAGCCTTTGGTCGCACTCCTTGTGAGTGCGTGGATTGAAATACTGAGACGCTAGACGCTATTAGATCACAGTCACGTCGCACTCCTTGTGAGTGCGTGGATTGAAATATCAAGCTTGCCAACGGGTCGATTTTATTCTGTGAGTCGCACTCCTTGTGAGTGCGTGGATTGAAATTTTTGAATAGATGGCATGTAAGTCTGATATAGTTGTCGCACTCCTCGTGAGTGCGTGGATTGAAATTTTAGGTCCATTGCACTCTTGCCAGTGAAGTCGTGTCGCACTCCTTGTGATGCACTTGTGGGTGTA

>NC_018528|1|1|580774-583005|PILER-CR
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AATGACTGATGAACAAAAGACAGCATTGAAGAAT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TGTTCAGCTCTATCTTGATGTCAAAGATCCTAACGG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATTCTGTAAGGACTGAAACACAAACTCTAAAATATA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATCGTTATGCAGGTATTACTACTGCTACTAATAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TCAGGAGATACTGCCGTTGGCTTTGAAGATAAATA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AATTCATTACTGGCATTACTCCAGTCACTGCGCCA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GAAAGGAAATATATATGTCAGTCAAAGTTAATGGT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GATTTTGTTAGAAAATTAACCGATGATTTTTTACA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TACCCACCTAGCTTAGCACCTACATGGAATGACA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CATTGTAGTAAAAGTTGCAGGGTCTTGAGTAAGAAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AATTAAGTCTAATCATAGGGGCAATAATTGCTTA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTTTTCGTCTTCTGCTCCTAGTGACTTAGTGAGCC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAGTGAATCGACAGGTATTGCAGATGATGATTTA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAGATGTGGAAGAGTGCAAGCACACACAGTCCCAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTAGAATACTTATGATCCTTAGATAGATGAACCG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CTCTGATCTGCTCAGCACGTTGCTCTTGCTTTGAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GATTATTCGGAACAACAGATGATCCTAAATGCTCA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CTAAAGCATACTTAGTAGCATATGAACTGGCTGAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TACAAACACTTGCCAACTTATAATCCACAAATGC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAAGGTGTGTGGATACCTGCTGAATATTGGTTAG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AGCATCAACGGCTCTAATTATGTCATTGCCGGTTT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACCTGATCAAACGTTAGGCAATAGATTAACCGAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTTACGAATGTCTTGCCAATTAGTATATTTACTT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AGAATCAAGACCACCTGTTAGCGTTTTACCACCG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAAGAACATAGTTTGCAGAACTGTTTCCAAGTAAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GGCTTTAGATGCGTCAAATGCCGCCTGTGGGCTATC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AGAAGATGGATACAATTTTTAGAAATTCCAGTCT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACACCATATGTGGTCAACGCTTTAATTGGATTACG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACTAACTGGAACATCCAAGTACTGTGCGGAAACC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATCGGCTAATTGCTTTTCAAGTGAATCAGCCTTTG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACTGAGACGCTAGACGCTATTAGATCACAGTCAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATCAAGCTTGCCAACGGGTCGATTTTATTCTGTGA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTTTGAATAGATGGCATGTAAGTCTGATATAGTT
GTCGCACTCCTCGTGAGTGCGTGGATTGAAAT

>NC_018528|1|1|580774-583005|CRISPRCasFinder
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AATGACTGATGAACAAAAGACAGCATTGAAGAAT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TGTTCAGCTCTATCTTGATGTCAAAGATCCTAACGG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATTCTGTAAGGACTGAAACACAAACTCTAAAATATA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATCGTTATGCAGGTATTACTACTGCTACTAATAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TCAGGAGATACTGCCGTTGGCTTTGAAGATAAATA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AATTCATTACTGGCATTACTCCAGTCACTGCGCCA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GAAAGGAAATATATATGTCAGTCAAAGTTAATGGT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GATTTTGTTAGAAAATTAACCGATGATTTTTTACA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TACCCACCTAGCTTAGCACCTACATGGAATGACA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CATTGTAGTAAAAGTTGCAGGGTCTTGAGTAAGAAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AATTAAGTCTAATCATAGGGGCAATAATTGCTTA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTTTTCGTCTTCTGCTCCTAGTGACTTAGTGAGCC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAGTGAATCGACAGGTATTGCAGATGATGATTTA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAGATGTGGAAGAGTGCAAGCACACACAGTCCCAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTAGAATACTTATGATCCTTAGATAGATGAACCG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CTCTGATCTGCTCAGCACGTTGCTCTTGCTTTGAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GATTATTCGGAACAACAGATGATCCTAAATGCTCA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CTAAAGCATACTTAGTAGCATATGAACTGGCTGAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TACAAACACTTGCCAACTTATAATCCACAAATGC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAAGGTGTGTGGATACCTGCTGAATATTGGTTAG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AGCATCAACGGCTCTAATTATGTCATTGCCGGTTT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACCTGATCAAACGTTAGGCAATAGATTAACCGAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTTACGAATGTCTTGCCAATTAGTATATTTACTT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AGAATCAAGACCACCTGTTAGCGTTTTACCACCG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAAGAACATAGTTTGCAGAACTGTTTCCAAGTAAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GGCTTTAGATGCGTCAAATGCCGCCTGTGGGCTATC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AGAAGATGGATACAATTTTTAGAAATTCCAGTCT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACACCATATGTGGTCAACGCTTTAATTGGATTACG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACTAACTGGAACATCCAAGTACTGTGCGGAAACC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATCGGCTAATTGCTTTTCAAGTGAATCAGCCTTTG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACTGAGACGCTAGACGCTATTAGATCACAGTCAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATCAAGCTTGCCAACGGGTCGATTTTATTCTGTGA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTTTGAATAGATGGCATGTAAGTCTGATATAGTT
GTCGCACTCCTCGTGAGTGCGTGGATTGAAAT

>NC_018528|1|1|580774-583071|CRT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AATGACTGATGAACAAAAGACAGCATTGAAGAAT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TGTTCAGCTCTATCTTGATGTCAAAGATCCTAACGG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATTCTGTAAGGACTGAAACACAAACTCTAAAATATA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATCGTTATGCAGGTATTACTACTGCTACTAATAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TCAGGAGATACTGCCGTTGGCTTTGAAGATAAATA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AATTCATTACTGGCATTACTCCAGTCACTGCGCCA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GAAAGGAAATATATATGTCAGTCAAAGTTAATGGT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GATTTTGTTAGAAAATTAACCGATGATTTTTTACA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TACCCACCTAGCTTAGCACCTACATGGAATGACA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CATTGTAGTAAAAGTTGCAGGGTCTTGAGTAAGAAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AATTAAGTCTAATCATAGGGGCAATAATTGCTTA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTTTTCGTCTTCTGCTCCTAGTGACTTAGTGAGCC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAGTGAATCGACAGGTATTGCAGATGATGATTTA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAGATGTGGAAGAGTGCAAGCACACACAGTCCCAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTAGAATACTTATGATCCTTAGATAGATGAACCG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CTCTGATCTGCTCAGCACGTTGCTCTTGCTTTGAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GATTATTCGGAACAACAGATGATCCTAAATGCTCA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	CTAAAGCATACTTAGTAGCATATGAACTGGCTGAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TACAAACACTTGCCAACTTATAATCCACAAATGC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAAGGTGTGTGGATACCTGCTGAATATTGGTTAG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AGCATCAACGGCTCTAATTATGTCATTGCCGGTTT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACCTGATCAAACGTTAGGCAATAGATTAACCGAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTTACGAATGTCTTGCCAATTAGTATATTTACTT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AGAATCAAGACCACCTGTTAGCGTTTTACCACCG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AAAGAACATAGTTTGCAGAACTGTTTCCAAGTAAA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	GGCTTTAGATGCGTCAAATGCCGCCTGTGGGCTATC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	AGAAGATGGATACAATTTTTAGAAATTCCAGTCT
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACACCATATGTGGTCAACGCTTTAATTGGATTACG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACTAACTGGAACATCCAAGTACTGTGCGGAAACC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATCGGCTAATTGCTTTTCAAGTGAATCAGCCTTTG
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ACTGAGACGCTAGACGCTATTAGATCACAGTCAC
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	ATCAAGCTTGCCAACGGGTCGATTTTATTCTGTGA
GTCGCACTCCTTGTGAGTGCGTGGATTGAAAT	TTTTGAATAGATGGCATGTAAGTCTGATATAGTT
GTCGCACTCCTCGTGAGTGCGTGGATTGAAAT	TTTAGGTCCATTGCACTCTTGCCAGTGAAGTCGT
GTCGCACTCCTTGTGATGCACTTGTGGGTGTA

Protein	Signature genes	Signature genes Name	Protein_function
NC_018528.1\|WP_014918445.1\|587168_587771_+\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|234620
NC_018528.1\|WP_014918440.1\|570744_572004_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|234856
NC_018528.1\|WP_014918449.1\|592831_593203_+\|ACT-domain-containing-protein	unknown	unknown	gnl\|CDD\|226131
NC_018528.1\|WP_080588347.1\|596445_596979_+\|translation-initiation-factor-IF-3	unknown	unknown	gnl\|CDD\|234582
NC_018528.1\|WP_014918444.1\|586341_587172_+\|DNA-formamidopyrimidine-glycosylase	unknown	unknown	gnl\|CDD\|234899
NC_018528.1\|WP_012212136.1\|575054_575798_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|273847
NC_018528.1\|WP_012212133.1\|578627_579284_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|273040
NC_018528.1\|WP_014918447.1\|589606_590515_+\|primosomal-protein-DnaI	unknown	unknown	gnl\|CDD\|236353
NC_018528.1\|WP_012212134.1\|577773_578625_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	COG3649_cas7_CAS-I-C	gnl\|CDD\|187820
NC_018528.1\|WP_014918438.1\|568592_569189_+\|phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|187714
NC_018528.1\|WP_014918443.1\|583669_586333_+\|DNA-polymerase-I	unknown	unknown	gnl\|CDD\|235591
NC_018528.1\|WP_012212135.1\|575797_577771_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	pfam09709_cas8c_CAS-I-C	gnl\|CDD\|378245
NC_018528.1\|WP_014918441.1\|579280_580312_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_018528.1\|WP_014918439.1\|569190_570732_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	unknown	unknown	gnl\|CDD\|234854
NC_018528.1\|WP_014918450.1\|593209_594460_+\|DUF389-domain-containing-protein	unknown	unknown	gnl\|CDD\|377221
NC_018528.1\|WP_014563206.1\|572505_575040_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_018528.1\|WP_014918448.1\|590805_592740_+\|threonine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234752
NC_018528.1\|WP_014918446.1\|588243_589575_+\|DnaD-domain-protein	unknown	unknown	gnl\|CDD\|226138
NC_018528.1\|WP_003627138.1\|587773_588241_+\|transcriptional-repressor-NrdR	unknown	unknown	gnl\|CDD\|234774
NC_018528.1\|WP_014563208.1\|580321_580612_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856

Protein	Function_ID	Function_description	E-value
NC_018528.1\|WP_014918445.1\|587168_587771_+\|dephospho-CoA-kinase	gnl\|CDD\|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	4.5835e-84
NC_018528.1\|WP_014918440.1\|570744_572004_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NC_018528.1\|WP_014918449.1\|592831_593203_+\|ACT-domain-containing-protein	gnl\|CDD\|226131	COG3603, COG3603, Uncharacterized conserved protein [Function unknown].	4.06666e-35
NC_018528.1\|WP_080588347.1\|596445_596979_+\|translation-initiation-factor-IF-3	gnl\|CDD\|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	1.09675e-87
NC_018528.1\|WP_014918444.1\|586341_587172_+\|DNA-formamidopyrimidine-glycosylase	gnl\|CDD\|234899	PRK01103, PRK01103, bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase.	1.75738e-155
NC_018528.1\|WP_012212136.1\|575054_575798_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|273847	TIGR01876, cas_Cas5d, CRISPR-associated protein Cas5, subtype I-C/DVULG. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This small Cas family is represented by CT1134 of Chlorobium tepidum. This family belongs to a set of several Cas protein families, one each for a number of different CRISPR/Cas subtypes, that share a region of N-terminal sequence similarity modeled by TIGR02593. This family represents the Dvulg subtype of CRISPR/Cas locus.	2.66247e-86
NC_018528.1\|WP_012212133.1\|578627_579284_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	6.87674e-27
NC_018528.1\|WP_014918447.1\|589606_590515_+\|primosomal-protein-DnaI	gnl\|CDD\|236353	PRK08939, PRK08939, primosomal protein DnaI; Reviewed.	1.29781e-152
NC_018528.1\|WP_012212134.1\|577773_578625_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|187820	cd09689, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Csd2 family.	6.96291e-109
NC_018528.1\|WP_014918438.1\|568592_569189_+\|phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|187714	cd08645, FMT_core_GART, Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART). Phosphoribosylglycinamide formyltransferase, also known as GAR transformylase or GART, is an essential enzyme that catalyzes the third step in de novo purine biosynthesis. This enzyme uses formyl tetrahydrofolate as a formyl group donor to produce 5'-phosphoribosyl-N-formylglycinamide. In prokaryotes, GART is a single domain protein but in most eukaryotes it is the C-terminal portion of a large multifunctional protein which also contains GAR synthetase and aminoimidazole ribonucleotide synthetase activities.	9.45834e-93
NC_018528.1\|WP_014918443.1\|583669_586333_+\|DNA-polymerase-I	gnl\|CDD\|235591	PRK05755, PRK05755, DNA polymerase I; Provisional.	0
NC_018528.1\|WP_012212135.1\|575797_577771_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	2.97564e-90
NC_018528.1\|WP_014918441.1\|579280_580312_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	8.25424e-171
NC_018528.1\|WP_014918439.1\|569190_570732_+\|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase	gnl\|CDD\|234854	PRK00881, purH, bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional.	0
NC_018528.1\|WP_014918450.1\|593209_594460_+\|DUF389-domain-containing-protein	gnl\|CDD\|377221	pfam04087, DUF389, Domain of unknown function (DUF389). Family of hypothetical bacterial proteins with an undetermined function.	7.09559e-51
NC_018528.1\|WP_014563206.1\|572505_575040_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.63297e-58
NC_018528.1\|WP_014918448.1\|590805_592740_+\|threonine--tRNA-ligase	gnl\|CDD\|234752	PRK00413, thrS, threonyl-tRNA synthetase; Reviewed.	0
NC_018528.1\|WP_014918446.1\|588243_589575_+\|DnaD-domain-protein	gnl\|CDD\|226138	COG3611, DnaB, Replication initiation/membrane attachment protein [DNA replication, recombination, and repair].	1.09245e-34
NC_018528.1\|WP_003627138.1\|587773_588241_+\|transcriptional-repressor-NrdR	gnl\|CDD\|234774	PRK00464, nrdR, transcriptional repressor NrdR.	6.49925e-87
NC_018528.1\|WP_014563208.1\|580321_580612_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.68589e-27

>NC_018528.1|WP_014563208.1|580321_580612_+|CRISPR-associated-endonuclease-Cas2
MMVVVSYDINTESKSGQRRLRHVAKICLDYGQRVQNSVFECKVNSMQLELMKERLLDEIDDSQDSLYFFNLGKNYKNRIKSYGIKEVINLESPVIF
>NC_018528.1|WP_014918441.1|579280_580312_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MRQLLNTLYINTPDSYLSSDGNNVVVKIKNNAVGRLPLQNFEAIVTFGYSGVSPSLMQKCLEQDISISFLSRTGRLKGRVVGEPTGNVYLRKTQFFNSENDAASLLIAKNMIIGKVYNHRWIIERFIRDHGMQIDRDKFKSISENLKNGLKDLQQVDTIDSLRRLEGSLANGYFSVFDDMIINQKDDFFYHGRSRRPPLDRLNALLSFSYSLLANECADALTTNGLDPYEGFMHVDRPGRKSLALDLMEELRGVIADRFVLRLVNKKEIHASDFVCKADGAYLLTDDARKSFLAKWQDNKISELEHPFLKEKIEWGLVPFAQAQLLARYLRGDLDEYPPFMWK
>NC_018528.1|WP_012212133.1|578627_579284_+|CRISPR-associated-protein-Cas4
MSYDEKDYLMISGIQHFVFCKRQWALDHIENQWADNYLTVSGNRLHEKADDPYISETRGSKFVVRAMPIHSQEYGLTGIFDVVEFQKDTKGVQVFGKKEKYLPIPVEYKHGKSKIDDSDRLQVLAEAVCLEEMLFCHLDYGYLYYGRTRHREKVEFSEELRTELKKVISEMHYYWEKKYTPKVKVTKKCKSCSLRDICLPELLKRESVSNYISRKLNQ
>NC_018528.1|WP_012212134.1|577773_578625_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MVLSNKIDFKVYVAVHGANPNGDPLNGNRPRQTNDGFGEISDVAIKRKIRNRLQDMGHKIFVQSADRTDDGFKSLKDRADSIDAIKKAAKAKDADKYAEVACKNWMDVRSFGQVFAFKGDKLSVGVRGPVSIQTARSISPIFINEMQITKSVNSTTGDKKSSDTMGMKYSIDFAVYEFGGSINVQLAEKTGFSDDDAESIHKALETLFENDESSARPAGSMEVLRVYWWKHNSKLGQHSPAEMNRAVEIKNNNEPNAPRSLDDIEFIDKTPEDMKENEQIYEG
>NC_018528.1|WP_012212135.1|575797_577771_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MNWISDLAKVYDDNESIAGKAETVSVGKEKTKTVTLVPISHIAVNIPIQINLDKDGGFKGADVIDEKDNQRTIIPATLKSASRSSGSAPMPIDDTLKYIAKDYYPEISNKDKDSHYYSDYINQLKGFVEYVNNKNSSDRVRQQVNAIYTYVSQNDIFADLLFKAHLFGDEIKQVSAIPMKWTGKEEKPAVYKAITGDLDRSFVRFNVRGLGLDRSFEDPDLYEAWGKYYLTTLRNDTGVDYVDCNNDAILTDNHPKGIIPSASNAKLISANDTTNYTFKGRLLNSDEVATIGYLNSQKAHHALRWLIDKQGFSIGGRYYLAWGRKQQNYMIDNQTSPMFKILTSTYNTDQAESYTNERLAKSYYNSLVKGIELNGDNLEDLVYLMQIDTSTPGRADIVSYQALDLNQYIRKLSSWYGKISLFIQNKAGEFVDPPYSLRTIANMIHGSKANDDLKKNTISELISVILGSQIVPRGIIMPLYNKAIRPLSFNPKDPEARFIGWQPIVRLTSKLLKIWYENEGIKAMLNDEINDRSYLYGRLLAVADVLEGDALKNKEVDRPTNAQRYMSAFAQRPADTWKTIYMNAQPYFKQSKGNRRGQILIDHIFDKLQINEENINRLNDPLDGKFLIGYSQQKVDWFRKIREYSEKKQKEQEKGDK
>NC_018528.1|WP_012212136.1|575054_575798_+|type-I-C-CRISPR-associated-protein-Cas5
MLNEIIKSPSFSYKVFGDWALFTDPIMRLGGEKFTYSIPTYQALKGIAESVYWKPTIVIHIDKVRVMKPILVEAKDMRLFKYNNSRSSDLARYTYLKDVEYQVLAHFEFNMNRLDLAKDRNIKKHLAIMKRCIKRGGRRDVFLGTRECQGYVEPCKFGEGEGYYDNSDDRLFGTMFHGFDYPDETGNSMLKARLWNVVMKKGVVDFIRPEDCPVHKPLHELQVKKFKKGENLESVDQLYSQMLEGDS
>NC_018528.1|WP_014563206.1|572505_575040_+|CRISPR-associated-helicase/endonuclease-Cas3
MVGNFIGHTKKLKNNTIETQSLRDHLLNTQKYAEKYASDLSLEHVAGLAGILHDLGKYQSKFQEYIIESTRKGDQSKKGSIDHSSFGAIFLRDFISENFSEKENYYDFLDFGGILENAIFSHHNYLGLKDYINPDLMSPFLNRIEKFKDDEEKKRQLKKCKELFYKDVITEEKFTKYFQLAFDEYEAFISKIRNKVTLKTEQILNENAKNNKQVMLELQAKYFLSEYVYSCLLDADRTDATAFKLSKNPNFSDNTELFEKYYSKLVGKLHKLNKNDNSKINQLRAEISEECDQAAERPSGIYTLSASTGSGKTLTSLRFGLKHAKLYHKKHIIYVLPYITIIEQNSEVIRKFLNDNKDDSQNILEFHSNVSQKVADKSEETTNALDLTEDSWDSPIIVTTMVQFLDSIFASGTKHRRRFHNLCDSIVIFDEVQKVPIKCLDMFNEAVNFLKNFGNTNVLLCTATQPALEEVKQKLDLNIDHEIIPNLIEHEQQFKRVEFIDKTQNDDGIDLVLNSIQAAELIFKKSQNFKSILGIFNTIDVTKKIYSNLKNKFDSISDQIKLEYLSTNMCPADRKERIKNVLNLVKEGKRVICISTPLIEAGVDASFECVFRSLSGLDSLVQAAGRCNRNNELKLGKVYLLNMDPSEEHIAKLNEVKTGKDQVLELLSEGIKADDFLNANVIKKYFEMFYSKLASTMSYPTNGINLENYIDGIKNVHELAYQSKRKDASKFEKLTQFSGSETIAKYFQVIKNNTKSVLAPYGDKGEKLIADLNGNQDINSLIMLVKDAQPYIVNLYDNKFNQLFEEGDIYTLCQVGNEVIYAFRPYAYNKLVLGDRKQIEKSIF
>NC_018528.1|WP_014918440.1|570744_572004_+|phosphoribosylamine--glycine-ligase
MKDDLVLLVVGSGGREFAVAKKLQESPHVKTVYCAPGNVGMQTIGVETVPIEETDLDGLLDFAKSKHVDWTFVGPENVLCAGITDKFEKAGQKIFGPNQRAAQLEGSKDYALRFMNKYDVPTARHETFTSAETCIAGLKDFDFPVVIKEDGLAGGKGVTIAKNQDVAEETIREMFAGGQTAVVLEECLVGPEYSMFVVVSEDQFTILPMAQDHKRVGDGDKGPNTGGMGSYSPLPQLKKEDRQKMIDEIVKPTMNGLVQGNYHYCGVLYIGLMLTEDGPKVIEYNVRLGDPETQVVLPRVKNDFAELIDAAVNHEKLPEIEENDQSVLGVVVCSKGYPTHPAPNVKIGKLPEGTNTYIDYANVKGDLDNLTGDGGRLFMVISEADNLVQAQDNVYSYLSKLDLPDCFYRHDIGNRALRD
>NC_018528.1|WP_014918439.1|569190_570732_+|bifunctional-phosphoribosylaminoimidazolecarboxamide-formyltransferase/IMP-cyclohydrolase
MKRALISVSDKTNLVDFAKGLVRNGYEIISTGGTKKTLDEAGIKTISVEEVTNFPEILDGRVKTLNPYIHGGLLAKRDDPEHMATLKKLNIQPIDLVCVNLYPFKQTIEKADVTREEAIENIDIGGPSLLRAASKNYQDVTVVTDKADYDLVLKEIEEKGNTTLETRAKLAAKVFRATAAYDAIIANYLTKQVGLEDPEKLTLTYDLKEKMRYGENSHQKAWLYEDAIPKSFSILQAHQLHGKKLSYNNIKDADEALRCIREFQDEPTVVAMKHMNPCGIGRGDTLEEAWDRAYEADSVSIFGGVIALNRKVDLATAEKMHKIFLEIIIAPGFDDDALAVLEKKKNVRLLELDFSKENEKTRPEVVSVMGGILQQEQDTLIENTDDWKVVTKAEPTAAQLKTMMFALKAVKHTKSNAIVVANDERTLGVGAGQPNRIDSAKIAINHAGDAIDDRAVLASDAFFPFNDCVEYAAKHGIKAIVQPGGSIRDKDSIEMADKYGVAMVFTGYRHFRH
>NC_018528.1|WP_014918438.1|568592_569189_+|phosphoribosylglycinamide-formyltransferase
MRVAILASGNGTNFEALTKKFQAGEIPGTEALMFCNHPNAPVVKRAERLGIPHEAFSVKECGGKTAYEKRLLKVLQDYQIDFIVLSGYLRVVGPTILNEYPNAIINLHPALLPSYPGLNSIERAFEDYKQGKIKETGVTVHFIDAHLDHGPIIAQQAVPIYPDDTVETLEARVHETEHQLFPATLKKVLSQRMEKEEN
>NC_018528.1|WP_014918443.1|583669_586333_+|DNA-polymerase-I
MADKKLLLIDGNSVAFRAFYALYRQLESFKSPDGLHTNAIYAFKNMLDVLLKDVDPTHVLVAFDAGKVTFRTKMYGEYKGGRAKTPEELLEQMPYIQEMLHDLGIKTYELKNYEADDIIGTFAAKGEKAGFTTTIVTGDRDLTQLASDKTTVEVTKSGVSQLEAYTPEHMKEVNGVTPTEFIDMKALMGDNSDNYPGVEGIGPKTASNLIQEYGSVENLYDHIDEMKKSKRKERLIRDKDKAFLAKKLATIDRDSPVTIDIDDVKREPVDYEKLWQFYEKMNFRKFLAELNASGAGQDGAEVEKVEYTVLNDDNVKDVKATEKDTVEFYLEMLGANYHLADFVGFSLKINDKIYVSRDVDLLEEDNIKHILEDEKIKKNVFDLKRSMVGAHRLGIHTHGLDYDMLLASYLVNNENNSNDLGEIAHLYGDYSVKTDLEVYGKGKSEHIPDDDDELFNHLASKVNAIESLKKTLLEKLKDHEQDDLFDTIEIPTARVLAKMEINGMKVEASTLIQLQNEFAVKLQDLEKKIYQQAGEEFNLNSPKQLGHILFEKLGLPVLKKTKTGYSTSVEVLDQLKTQSPIVKEILDYRQIAKIQSTYVKGLLDVIQPDGRVHTRYLQTLTATGRLSSVDPNLQNIPTRTEEGKQIRKAFVPSDPDGYIFSCDYSQVELRVLAHVSGDQNMQEAFKTGYDIHSHTAMKIFHLESPDEVTPLMRRHAKAVNFGIVYGISDYGLSKNLGISRKRAQEFIDNYFEQYPQIKDYMNKAVQEARDKGYAETIMHRRRYLPDIHAKKYTVRAFAERTAINSPIQGSAADIIKIAMINMQKKLDELHLKTKMVVQVHDELIFDVPKDELETIKKIVPEVMQSAVKLDVPLIADSGWGHNWYDAK
>NC_018528.1|WP_014918444.1|586341_587172_+|DNA-formamidopyrimidine-glycosylase
MPEMPEVETVRRTLIPLIKGKTIEKVILWYPKIVATDHEKFLSELPGKKIIDIDRYAKYLLIRLSDNLTIVSHLRMEGKYHLTTSDAPKDKHDHVEFIFTDGTALRYNDVRKFGRMQLILTGTERQTTGIGKLGYEPNSSEFTSEYLVNGLKRKKKNIKNTLLDQSVVAGLGNIYVDEVLWRTKIHPLSQANKIPAEKVIELHDQINQIITEAIKLQGTTVHSFLNANGQVGGFQSKLQVYGHVGEPCSVCGTKFEKIKVNGRGTTFCPHCQVIYK
>NC_018528.1|WP_014918445.1|587168_587771_+|dephospho-CoA-kinase
MSYVLALTGGIATGKSTADDFFRKKNIPIIDCDQIAHELMEPGNASWQAIKDHFGMEYLNSDQTINRKKLGQLVFSNKQALSELNQVTHPLIFDKTVAKIKEYRDFALVILDVPVYFEAGLDKKHVANGVLVITLPEQLQIERLKKRNNLTDQEAINRINSQMPLVEKEKMADFVVANTGKIKELENKLEQILIKIREEE
>NC_018528.1|WP_003627138.1|587773_588241_+|transcriptional-repressor-NrdR
MECPNCHQNASRVIDSRPSDENRAIRRRRECENCGFRFTTFERIETAPLLVIKNDGTREPFNRKKILHGVMAAGQKRPISSDQFEQLVDHVENKVRKQGISEISSKKIGQYVMDELADLDDVAYIRFASIYREFKDMSSFMKTMEDMMAKKGKGN
>NC_018528.1|WP_014918446.1|588243_589575_+|DnaD-domain-protein
MFETADPKHLYYVANRVRLFPEDEKVLIKLYQPLVGAVAVALYQTLIQNYDPYGIISDSKGIYSLQEQLDCSLKQLFNSLHKLEAVGLVQTFLSDNVFNNVLVFKLLQVPAADKFFATPLLASLLKEKVGVPTFHDLSHAFAQDAKLKEKPIKNAKDVSANFFDVFRLPGDEAITPSSDVVQAAQENKVHEVETAKVNDHDSIDWDFIKQEYSRYQIPASEIDLNKEQIRGLIQTYGLSEKEFVDESLPCLHGSYSLNMRDISNTLAENYKRTNTRENVQSQLNEGRKKALAAIKDMDDNDKKLLKAANESSPAEFLYKLKTQKGGITSANEKQIINNLHTQYGLPEDLINILTYTCLTYDTVVSSNLAYKIANDWLQHGVATAVQALQYVKKRRNSFGKKRPVRTYQKRVEKGTDWSKKKADRDAGISTEQLKNLFKDLNNK
>NC_018528.1|WP_014918447.1|589606_590515_+|primosomal-protein-DnaI
MEPIDKVIKKIVKERNLGDEQSLISQALHDPDVQAFLTANANKIDQKMVQNSMSNLYEYYSQKHTANKVMAGYAPQLFLNGKVIDIRYVPTKAKLAQDRKQAAERRLQLIDVPTRLHDVSLSEIDVNDDRKQVLTLIYDFLRKYKQDPHVQGLYLSGDYGVGKTYILAGLANYVVTNMNKNVVFLHVPTFIAGLASHFDDNSLQSEIRRLSECDLLILDDIGAESLSQWSRDDVLGVILQARMDNVLPTFFSSNLDMEALESHFEETRNATDPVKARRLMQRVRFLAKEVVVSGPDRRNSLH
>NC_018528.1|WP_014918448.1|590805_592740_+|threonine--tRNA-ligase
MSFSITLPDGSKKDFEESLTIADLAHNIATSLGKAAVAGKVNGELKPLDYKLDSDSEVAIITNKDEEGLDVLRATAAFVFEAVAKREYPELRLGEHVADEGGFYVDTDKDDQIKVGELPKLEKAMQKVIKNGEKIEHVQIAKSELEDLYKNDKFKSEVLAKVEGDTVDAYKLGDFVDFGFDALLPNTGKIKQFKLLSVAGAYWLGKSSNPMLQRIFGTAFFKEADLKADLKRRQEIKERDHRTIGRDLDLFFVDPKVGAGLPYWMPKGATIRRVVERYIIDREVADGYQHVYTPVLMNLDAYKTSGHWAHYRDDMFPPMDMGDGEMLELRPMNCPSHIQIFKHHIRSYRDLPLRVAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVALDQVQTEFAKILKLIMDVYKDFDITDYYFRLSYRDPKNTDKYFANDEMWEKSQKMLKGAMDDLGLDYVEAEGEAAFYGPKLDIQTKTALGNDETMSTIQLDFMLPDRFGLTYVGKDGEEHRPVMIHRGIVGTMERFIAYLTEIYKGAFPTWLAPVQAEIIPVNNEAHGEYAEKVRAELAKRGFRVEVDDRNEKMGYKIRESQTQKVPYTLVLGDEEMKSGKVNVRCYGTDEEISKSLDDFINEIDADVKSYSREN
>NC_018528.1|WP_014918449.1|592831_593203_+|ACT-domain-containing-protein
MKLTIKKLPYQLTVCQLSDIKNLNLKNDFYFFAKTDEELSLVCENKNAPSKTINREDGWRAFKIEGQLDFSLIGILAKIAQLLANNGISIFAVSTFNTDYILVKDNNFDSAIKILSENNYEIK
>NC_018528.1|WP_014918450.1|593209_594460_+|DUF389-domain-containing-protein
MSRKNYLSPQFLTKISEDGTLNIESLIILTCAIFIASIGLNVNSTATIIGAMLISPLMGPLLAIGTGLALYNTNILRKGAISLLAEIVISLVASTIYFHFSPLTYASQEIIARTSPTIWDVMIAFFGGSAGIIGARKKGANNIVPGVAIATALMPPLCTVGYSIAAGNLKYFLGSGYLFLINCVFITLTAFLGVKIMKWLSHSAGQPGLSFFRKPTLKETGIVLVVIILIIPNVLSAGHMVNKTLVDQNVQNLVAHELGDVDLIKENVDSQEKTINLTVSGKKINAKKIQAAKANLAEYNLKGYSLNIVQVAQVNPNAENQLDRQVNNILNQRQCEQEQANEERQQEQEKHNQEIEKLSPAISSVTAVSDNKNKQITLIELKKNISAKKKKALVKQIKEKYPNINLVEFVQESEKE
>NC_018528.1|WP_080588347.1|596445_596979_+|translation-initiation-factor-IF-3
MPKSLILNERIRAREVRLIDEDGQQVGVVSKSEALHKASDAGLDLVLISPNAKPPVARIMDYGKYRFEQQKKLKESRKKSNTVSVKEIRLSPTIEGNDFETKLKHVRKFISKEGAKVRVSIRFRGRAITHKELGQQVLEKMAEATSDIANVISKPKMEGRSMFLMLAPKSDKDKKKK

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Crispr_ID: NC_018528_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018528_2

1611227-1611406

TypeV

Consensus_repeat	Method
ATGTGGGATTTGAACCCACGC	PILER-CR

2 spacers

cas14j

The CRISPR arrays of NC_018528_2

>merge|NC_018528|2|1611227-1611406|PILER-CR
ATGTGGGATTCGAACCCACGCATGCTGGATCCACAAACCAGTGTGTTAACCCCTTCACCAATTCCGCCATAAACGGTCCATGTGGGATTTGAACCCACGATCTCCTCCGTGACAGGGAGGCGAGATAAACCACTGCTCCAATGGACCAATCAGAGGAGGATGTGGGATTTGAACCCACGC

>NC_018528|2|2|1611227-1611406|PILER-CR
ATGTGGGATTCGAACCCACGC	ATGCTGGATCCACAAACCAGTGTGTTAACCCCTTCACCAATTCCGCCATAAACGGTCC
ATGTGGGATTTGAACCCACGA	TCTCCTCCGTGACAGGGAGGCGAGATAAACCACTGCTCCAATGGACCAATCAGAGGAGG
ATGTGGGATTTGAACCCACGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_018528.1\|WP_014919234.1\|1600170_1600986_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381359
NC_018528.1\|WP_157951888.1\|1603997_1604816_-\|bacteriocin	unknown	unknown	gnl\|CDD\|375122
NC_018528.1\|WP_014919241.1\|1609092_1609605_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_018528.1\|WP_014919245.1\|1614745_1615054_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376281
NC_018528.1\|WP_014919240.1\|1607210_1608983_-\|oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
NC_018528.1\|WP_014919246.1\|1615454_1616807_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NC_018528.1\|WP_014919250.1\|1619853_1620546_-\|DUF1211-domain-containing-protein	unknown	unknown	gnl\|CDD\|377696
NC_018528.1\|WP_014919243.1\|1613416_1613845_-\|hypothetical-protein	unknown	unknown	unknown
NC_018528.1\|WP_014919233.1\|1598787_1600116_+\|uracil-transporter	unknown	unknown	gnl\|CDD\|236744
NC_018528.1\|WP_014919232.1\|1598244_1598775_+\|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	unknown	unknown	gnl\|CDD\|235365
NC_018528.1\|WP_014564055.1\|1620612_1621533_-\|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl\|CDD\|237282
NC_018528.1\|WP_014919247.1\|1617169_1618546_+\|Na+/H+-antiporter-NhaC	unknown	unknown	gnl\|CDD\|188097
NC_018528.1\|WP_003633097.1\|1611574_1612075_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_018528.1\|WP_080588366.1\|1606272_1606809_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_018528.1\|WP_041808797.1\|1602564_1603641_-\|SLAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|367400
NC_018528.1\|WP_014919242.1\|1609612_1611079_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NC_018528.1\|WP_174225715.1\|1601040_1602264_-\|transposase	cas14j	-	gnl\|CDD\|223747
NC_018528.1\|WP_014919244.1\|1614059_1614257_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_018528.1\|WP_014919249.1\|1619104_1619809_+\|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl\|CDD\|198414
NC_018528.1\|WP_041808804.1\|1618582_1618897_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_018528.1\|WP_014919234.1\|1600170_1600986_-\|aldo/keto-reductase	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	4.27038e-144
NC_018528.1\|WP_157951888.1\|1603997_1604816_-\|bacteriocin	gnl\|CDD\|375122	pfam17312, Helveticin_J, Bacteriocin helveticin-J. Bacteriocins are biologically active proteins or protein complexes that display a bactericidal mode of action towards closely related species. Bacteriocins produced by lactic acid bacteria are grouped into different classes. Class III of bacteriocins includes large heat liable proteins. Lactobacillus helveticus 481 produces a 37-kDa bacteriocin called helveticin J which is a representative for Clas III bacteriocins.	8.46522e-83
NC_018528.1\|WP_014919241.1\|1609092_1609605_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.14851e-07
NC_018528.1\|WP_014919245.1\|1614745_1615054_-\|hypothetical-protein	gnl\|CDD\|376281	pfam18862, ApeA_NTD1, ApeA N-terminal domain 1. Mostly beta strands. Fused to HEPN (Apea). Several conserved aromatic residues, abundant but poorly conserved.	0.00145728
NC_018528.1\|WP_014919240.1\|1607210_1608983_-\|oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
NC_018528.1\|WP_014919246.1\|1615454_1616807_-\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	1.29845e-158
NC_018528.1\|WP_014919250.1\|1619853_1620546_-\|DUF1211-domain-containing-protein	gnl\|CDD\|377696	pfam06736, DUF1211, Protein of unknown function (DUF1211). This family represents a conserved region within a number of hypothetical proteins of unknown function found in eukaryotes, bacteria and archaea. These may possibly be integral membrane proteins.	1.00269e-14
NC_018528.1\|WP_014919244.1\|1614059_1614257_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	6.6753e-32
NC_018528.1\|WP_014919233.1\|1598787_1600116_+\|uracil-transporter	gnl\|CDD\|236744	PRK10720, PRK10720, uracil transporter; Provisional.	1.2211e-145
NC_018528.1\|WP_014919232.1\|1598244_1598775_+\|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	gnl\|CDD\|235365	PRK05205, PRK05205, bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR.	3.80023e-99
NC_018528.1\|WP_014919247.1\|1617169_1618546_+\|Na+/H+-antiporter-NhaC	gnl\|CDD\|188097	TIGR00931, Uncharacterized_Na+/H+_antiporter_HI_1107, Na+/H+ antiporter NhaC. A single member of the NhaC family, a protein from Bacillus firmus, has been functionally characterized.It is involved in pH homeostasis and sodium extrusion. Members of the NhaC family are found in both Gram-negative bacteria and Gram-positive bacteria. Intriguingly, archaeal homolog ArcD (just outside boundaries of family) has been identified as an arginine/ornithine antiporter. [Transport and binding proteins, Cations and iron carrying compounds].	5.74224e-110
NC_018528.1\|WP_003633097.1\|1611574_1612075_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.72017e-13
NC_018528.1\|WP_080588366.1\|1606272_1606809_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.86342e-07
NC_018528.1\|WP_041808797.1\|1602564_1603641_-\|SLAP-domain-containing-protein	gnl\|CDD\|367400	pfam03217, SLAP, SLAP domain. This short domain is found in a variety of bacterial cell surface proteins. The domain is about 60 residues in length (although previously defined as 2 copies of this domain). It usually occurs in tandem pairs. It may be distantly related to the SH3 domain.	2.26766e-07
NC_018528.1\|WP_014919242.1\|1609612_1611079_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.26867e-41
NC_018528.1\|WP_174225715.1\|1601040_1602264_-\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	4.69986e-45
NC_018528.1\|WP_014564055.1\|1620612_1621533_-\|diacylglycerol-kinase-family-lipid-kinase	gnl\|CDD\|237282	PRK13055, PRK13055, putative lipid kinase; Reviewed.	0
NC_018528.1\|WP_014919249.1\|1619104_1619809_+\|Bax-inhibitor-1/YccA-family-protein	gnl\|CDD\|198414	cd10432, BI-1-like_bacterial, Bacterial BAX inhibitor (BI)-1/YccA-like proteins. This family is comprised of bacterial relatives of the mammalian members of the BAX inhibitor (BI)-1 like family of small transmembrane proteins, which have been shown to have an antiapoptotic effect either by stimulating the antiapoptotic function of Bcl-2, a well-characterized oncogene, or by inhibiting the proapoptotic effect of Bax, another member of the Bcl-2 family. In plants, BI-1 like proteins play a role in pathogen resistance. A characterized prokaryotic member, Escherichia coli YccA, has been shown to interact with ATP-dependent protease FtsH, which degrades abnormal membrane proteins as part of a quality control mechanism to keep the integrity of biological membranes.	2.29842e-49

>NC_018528.1|WP_014919242.1|1609612_1611079_-|MFS-transporter
MNKKQITMVTIALMLGNVMSGLDGTIINTAIPTIVAALHGIQFMGWIVAIFLLGMSISIPIWTKIGEKITNKKAFEISLVLFVLGAALQGMAPNIIFFLCSRFIMGIGAGGMGSLPYIIAGYVFKNIKTRTKVLGYLTASWNGAAILGPLVGGWLIDAFSWHWVFYINIPIGLIALIICFIYYKPVTPEKTPVFDIPGAGLLVIGLLLFLMGVQLVGLTANWIVISLIIISLVFIVLFFIRENHAANPIIPVSLFKNKDLDGDFLLFAFTWGAFIAVNTYMPMWAQALLGLSALLGGMTLIPNSIVEIIASQSVAAIQEHMSTFKLALIGIIAMMISSAGLFLADIHTPVQMLTFIGAFSGIGVGFIFVAMQLKVQLDAGLKNMATATSTSYLIRILAQTVMAAVYGVIMNLNLASGVHTHKGITMAMMNKLSDAKSAKLLPQGLVPTMRTIFHAGIKEIMLVSLILLIIAFVLNFYFNFGKKRKKLQ
>NC_018528.1|WP_014919241.1|1609092_1609605_+|TetR/AcrR-family-transcriptional-regulator
MNMKSLHTQQHIEKALFSLLQKKPYAEISIAEITRKAHVSRTSFYRNYSQKNDVLMLFLANQYKKFIVDINEHKLKTLTKQLVAYLTFFKGNPKVMKILLDAGFEGSLLNFQTRYLKKLLSVYHPDLNLPDYAIAYQSGGIYMLLIWWVKQDYATPLEDLINYAEKHIML
>NC_018528.1|WP_014919240.1|1607210_1608983_-|oleate-hydratase
MHYSNGNYEAFVKAEKPKDVDQKSAYIVGSGLAALASAVFLIRDGQMKGNRIHIFEELSLPGGSMDGIYSKEKESYIIRGGREMEPHFECLWDLFRSIPSTEHEGESILDEFYRLNRKDPSYAKTRVIINRGEALPTDGQLLLTPKAVKEIVDLCLTPEKDLQNKKINEVFTKEFFQSNFWLYWSTMFAFEPWASAMEMRRYLMRFVQHVATLKNLSSLRFTKYNQYESLILPMVKYLKSHGVQFHYDTVVDNIFVNRSNGEKVAKQIILTEKGERKTIDLTENDLVFVTNGSITESTTYGDNFHPASEEHELGASWQLWKNLAAQDSDFGHPDVFCKDIPKANWRMSATITFKNDDIVPFIEAVNKKDPHSGSIVTSGPTTIKDSNWLLGYSISRQPHFKAQKPNELIVWLYGLFSDTKGNYVEKTMPDCNGIELCEEWLYHMGVPEERIPEMAAAATTIPAHMPYITSYFMPRALGDRPKVVPDHSKNLAFIGNFAETPRDTVFTTEYSVRTAMEAVYTLLDIDRGVPEVFASAFDVRMLMNALYYLNDQKKLEDLDLPMGEKLAIKGMLKKVKGTYIEELMKEYKLI
>NC_018528.1|WP_080588366.1|1606272_1606809_-|GNAT-family-N-acetyltransferase
MILDSKPARWGTKAYRDAKDLYMKAFPAWERFSMFSLLAMSLHRNVKFHAIYNEDQFCGITYYAENDKTVYLTYLAINEELRGQGYGSKILTMLEDRFLDKQIVIDIEPVTSKAKNYKQRVSRLKFYKRNGFHRTDQKLKDPDGEFEALTTGKKLDKESFIDTLRQMSFGFYQAKVEK
>NC_018528.1|WP_157951888.1|1603997_1604816_-|bacteriocin
MYVFRANKESYVPFNKNNPILIMDGQNGATAGGHTQTWEYANRTNEWFVGTKPKNKWTTQIARVHISSSTSRYTSNTQLPRLSYLNRAGSQQGINYAGADLKRVEAAVSPDYQYFMIATIDRYNTGYFSIYYLDDINTALDNAGVNDVNIQTLTSVKAFIIPSFVDNIGSIQGYDIDNGANYIYVSSQHSPGYEDISRKIVKIPWGSQNPSEWDFVRLDSNSTINSFSGNYQTEFESVQVIDNNNVWLTVAYHDMDTSTNLTVMNRIYKISW
>NC_018528.1|WP_041808797.1|1602564_1603641_-|SLAP-domain-containing-protein
MTRKIKMISLAAAALLAVAPVVSPAVVHAADTTSTTTTLNSNAENPVITYNGKKYDSNQDITAAIANSSFSRVPLKGSSTFIQDVKNAFSATESSTDNSKVNIVVYTGDLYTNIAGKYPVRVLATNKAGKSTALTFQVIVGNQGANATYAVAKPQVRGNVTLYTIRDGKVIHNSYGSYVLDGGTTVATFGTVEINGISYTRLNGPDSDLFIETKSVDGTYPESATNEDGQAKTVTKTLMHTAIAYNSDGHSTGKKYYAYRQLTLSAVKKNIKGSMYYNVQGTGDYIKVGNIDGTKRTLTRNAYIYATSKRRADRTLLRKGYTITTYGGSYKFKNGKRYYRIEGATSTNKRYVKVVNFK
>NC_018528.1|WP_174225715.1|1601040_1602264_-|transposase
MFDIILKRKEETNVLKGIKLRLYPNRTQQNQLEQMFGNDRFVWNQMLAMMNERYQNNKDLPFLGKFKLNYLLKPLKKEYPFLKNSDSSSLQVVNEFLTQSWKNFFQDKTGQIGKPRFHSRKYLKKSYTGKSIIKTAGKRYLKIPKLGYIKTSKIGVLQDVKIKRYTVVLEPTGKYYLSLQVEISEPEKYSLTGKQVGIDVGVADLAILSNGLKYPSFDSSYFEKKAKVWQRKCARRRHLAKLLVLQDRNKKVLCPRSLESFTNWQKAQKSIARYQAKIANQRRDYLHKLTTYLVKQYDVIAIEDLKTKNLQKNHHLAKSIANASWRMFRQMLEYKCEWYGKKLIAVDPKNTSRICSKCGYNSGAKPLEIREWTCSKCQTKHDRDINAAVNILHKATPTGQGLAMVTS
>NC_018528.1|WP_014919234.1|1600170_1600986_-|aldo/keto-reductase
MFPETRHFSAGVVHQINDLAQTQQVVEDGLEVGYRLVDTAQVYGNEQAVGDAIRHSNIPREDIFVTSKIWVDDYGYDATLKAFDETMKKLQLDYLDLYLIHKPYNDYYGTWRAMERLYKEGRIRAIGVSSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQKYMEKEGVQPEAWAPFAEGADHIFTNPVLEEIAEKHHKTTAQVMLRWFLQRNYVVIPKSVHKERLAQNFDIFDFELDKTDMEKIKTLDQGRSILEDEMDPEIAESFR
>NC_018528.1|WP_014919233.1|1598787_1600116_+|uracil-transporter
MSKKENFRNPDAILDVYEKPKFGQGVLLSLQHMFAMFGSTVLVPILIGINPSIALLSSGIGTLVHMILTHFKIPAYLGSSFAFVATMQALMKADGYPAVAQGAIASGLVYVIVALIIAKVGSGWVNKVLPPIVVGPIIIVIGLSLATTAANDAMMNNQKYDLTYFGVAIFTLVMTLVFQMCFKGFTSLVSIMLGIICGYVLACFLGIVDFSGVEKAAWFSIPSLDVMGISYHFKWYPAAILAMAPIAFVTMTEHMGHIMVLNSLTKRNFFKNPGLHRTMMGDGISTIIAGFIGGPPTTSYGENIGVLAMTKVHSVWVLAGAAVCAIIFSFVGKLAALIESIPMPVIGGISFLLFGTIASNGLKILVDDKVDFGEKRNMLITSVILVIGIGGAYLQLGNFQLTSVALSTIIGMILNWVLPKQAASEKALAEKNKEKQEGKIYQ
>NC_018528.1|WP_014919232.1|1598244_1598775_+|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR
MAKEIIDAIGMKRALMRMTYEIVERNKGTENLVLVGIKTRGLYLAQRIAANLKKLEDVEITVGAIDVSQYRDDLPESKKEKMIHDQQLDFDITDKNVVLVDDVLFTGRTIRAALDALMDQGRPAKINLAVLVDRGHRELPIRPDFIGKNIPTAMNEEVKVSMTEVDDKDSIELINK
>NC_018528.1|WP_003633097.1|1611574_1612075_-|GNAT-family-N-acetyltransferase
MIIKPLISEDEAKETSRLFQKCWQNTYKDILPDVFLDNIPENAWVKRLNESGRHNLIFIDDDNKIRAAVSYGRPRDTRMLGCGELMALYVEPDFQGFNIGKTLLNAAENELKKMGYGKIYLWCIDGDENARQFFEHFGWVNNATEKFVEIAGKEYKYLLYQKNLHD
>NC_018528.1|WP_014919243.1|1613416_1613845_-|hypothetical-protein
MINNWVSSSKELQLLVDDYLLTVNYRSVIENDLVNYTQGIESYFRNERLTLRDKINKFIEELPESYRELLSEHVGNTDDWIGKLVSTRVFLTHGDRENMVVSNPYKLVQMTKIFDFMVRIFILQKLGITIDKPKILNKDQNV
>NC_018528.1|WP_014919244.1|1614059_1614257_+|cold-shock-protein
MQGTVKWFNADKGFGFITGSDGKDAFVHFSSIKTDGFKSLEEGQKVSYDVEQGDRGPQATNVVPQ
>NC_018528.1|WP_014919245.1|1614745_1615054_-|hypothetical-protein
MKNKISDKNMFQNFEVKAYWFLNDNQNSGSYGFLKYNAGQDSVFEISPAFCDKTEQFNSPSPYDICGISEYGEIIRGIGYRVGSSFNHPGLSIEKIQFFDLK
>NC_018528.1|WP_014919246.1|1615454_1616807_-|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MEKNQIIDLEITDLSYEAMGVAHYNGMTVFVTNALPGEVVSAKILKVKKNFAFAKIEKIKKESPDRVKVKLNQGVQSGLASLAHIKYDKQLDFKRNQVVNLLKKAHLENIEVGETLASPEEVGYRNKAQVPVREVNGQLEIGFFRRHSHDLMPLTHFFTTDPEIDRVLVAVRDILRKYKVPAYDEINNKGEVRYLEVRRSKSTGEMMVILVCLHKDFMQLPNVAAEVSQIPGVSGLILNHNPKKTNVILGPKDYLVFGNDQITDQIGDLKFRISPQSFFQINSLQTPRLYNLAIKQADLKPDDVVIDAYSGIGTIGLSVAKHVKAVRGIEVVRDAIKDAKDNAKLNDITNAKYYLGKAEEIMPRWAKSGLKTDVVFVDPPRKGLTPEFINAAVKTGPKKIVYISCNPATLVRDLQLFQEKSYEFNRIDPVDMFPQTPHVESVTVLERTEK
>NC_018528.1|WP_014919247.1|1617169_1618546_+|Na+/H+-antiporter-NhaC
MKKEKVSFTESIIILIALLAILGISVIKFGLSPEVPVLFTVLLLTFWARFRGFTWKDVQDGIKEGIGVAIIPIFIFILIGALIGLWIKAGIIPSIMVLGFHLISGSFFVPSVFIVCAIVGVAIGSGFTTISTVGIALFGIGASMNANPALVAGAIISGAVFGDKMSPLSDSTNLSSAVTESELFDHIKNMMWSTIPSFVVSLILFWILGNSGHMDPTKIERTSHVLQINFSISWWAVVPIVLMLLCAWRKVPAIPTLFVNIAATVIMIFVQNPHESVQSLNNLIMNGFVAKTSDASVNALLTRGGISSMMATVALIISTLSLGGMLMKFNVVQSAMEPLVKHLRKPGRLITVTILSGICINLFVGEQYLSVILPGRAFKPAFDKIKLSPLALSRVLEDGGSVINYLIPWGVAGSFAAATLGVPVLQFLPFAFFSLLSPVFSIISGFTGIGLKWAKDKK
>NC_018528.1|WP_041808804.1|1618582_1618897_-|hypothetical-protein
MRGERSSRPEQVEKQALTLSFTKNAWDKYRQLTGSQKTFIDSELDDLKFNQNRQKSKQVNAELDQALVFEKNDAEIVITDIGYEPYRESQEHKKAQIRMEDMNN
>NC_018528.1|WP_014919249.1|1619104_1619809_+|Bax-inhibitor-1/YccA-family-protein
MDNFSNPGHREVHDVSEVNGFLSKMYGYMGLSVLVSALAAFLTMTVFRSAVMQMPPAMMWIILFVPIGLSLGINFKATRNPVAGFVMLMILAVIYGFEFALLAGFYTQAQIGTAFVSSAAVFGAMAVFGTFTKKNLNNMGSYLSAALIGLLVAMVVNIFLRNSVASFVFSIIGVVIFTGLTAYDAQKMKAIYNNYGSQVSTNGLAVLGALQLYLDFVNIFLFLLQIFGMGGDRD
>NC_018528.1|WP_014919250.1|1619853_1620546_-|DUF1211-domain-containing-protein
MFKLHKVFDSRHYRRLSSVQKEELKEARDKVHQAQQKEPERLREHLETFNDAVIAIIITIIVLQIQPAFKASQYLEFLGNIVTFIIAFFIIADFWYELHLAFSYFIFKPDKITAICDFCLLATLSLLPVMTKWIMMHDSAFAVTNFGIVYFIAQILKVFVQYFGAKPLMRSSQVMNIMMVKTSVHRIILVFLLTIFLILLSLVVPKVAMVLYILIPFISFFKPNNSRGFR
>NC_018528.1|WP_014564055.1|1620612_1621533_-|diacylglycerol-kinase-family-lipid-kinase
MTSKARLIYNPVSGHEQMPKNVADILDVLEQAGYEASAFRTTPEENSARNEATRAAKEGFDLIVAAGGDGTINEVVNGIAFLEKRPKMAIIPAGTTNDYARALAIPRDNIPDAAKVILKNKTRKMDIGKAVFGNQTQYFVNIAASGSLTELTYGVPSEVKSALGYAAYLIKGAEMLPHLSENEMRLTYDDGVYEGKLSMFLLGMTNSIGGFEQVMPDAQLSDGLFQLLVVKPSDPVSMMKLMALALNGKHVDDPNIIYTKTRSLKAELIGKSEGQDLPVNLDGEIGGYCPVEFKNLQQRIEFYVGK

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Crispr_ID: NC_018528_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_018528_3

1953579-1953731

Orphan

Consensus_repeat	Method
TTTGAACAAAACACATCATATACCATATTAGTTCGAATATCAAACTATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_018528_3

>merge|NC_018528|3|1953579-1953731|CRISPRCasFinder
TTTGAACAAAACACATCATATACCATATTAGTTCGAATATCAAACTATTCTGGTTAACGGCATTGTATACGGGTTGCGAGGACCCGTAAAGATTTTTTTAAATATTTGAACAAAACACATCATATACCATATTAGTTTGAATATCAAACTATT

>NC_018528|3|2|1953579-1953731|CRISPRCasFinder
TTTGAACAAAACACATCATATACCATATTAGTTCGAATATCAAACTATT	CTGGTTAACGGCATTGTATACGGGTTGCGAGGACCCGTAAAGATTTTTTTAAATA
TTTGAACAAAACACATCATATACCATATTAGTTTGAATATCAAACTATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_018528.1\|WP_014919523.1\|1946048_1947428_-\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	unknown	unknown	gnl\|CDD\|236307
NC_018528.1\|WP_014919527.1\|1953023_1953470_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	unknown	unknown	gnl\|CDD\|234568
NC_018528.1\|WP_014919525.1\|1950318_1951236_-\|ACP-S-malonyltransferase	unknown	unknown	gnl\|CDD\|223408
NC_018528.1\|WP_013855208.1\|1947862_1948333_-\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	unknown	unknown	gnl\|CDD\|235777
NC_018528.1\|WP_014919544.1\|1975811_1976591_+\|indole-3-glycerol-phosphate-synthase-TrpC	unknown	unknown	gnl\|CDD\|234710
NC_018528.1\|WP_014919526.1\|1951546_1952530_-\|ketoacyl-ACP-synthase-III	unknown	unknown	gnl\|CDD\|236475
NC_018528.1\|WP_014564299.1\|1948336_1949566_-\|beta-ketoacyl-ACP-synthase-II	unknown	unknown	gnl\|CDD\|274452
NC_018528.1\|WP_014564300.1\|1949587_1950319_-\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|235500
NC_018528.1\|WP_014919531.1\|1958944_1961212_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|223256
NC_018528.1\|WP_014919535.1\|1964212_1965562_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|180907
NC_018528.1\|WP_014564315.1\|1956358_1957198_+\|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl\|CDD\|181221
NC_018528.1\|WP_014919539.1\|1971080_1971320_+\|integrase-core-domain-containing-protein	unknown	unknown	gnl\|CDD\|372570
NC_018528.1\|WP_014919543.1\|1974789_1975815_+\|anthranilate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234682
NC_018528.1\|WP_014919545.1\|1976593_1977181_+\|phosphoribosylanthranilate-isomerase	unknown	unknown	gnl\|CDD\|238237
NC_018528.1\|WP_014919524.1\|1947441_1947858_-\|beta-hydroxyacyl-ACP-dehydratase	unknown	unknown	gnl\|CDD\|238615
NC_018528.1\|WP_014564303.1\|1952526_1952994_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_018528.1\|WP_174225720.1\|1971437_1972694_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340911
NC_018528.1\|WP_014564315.1\|1967252_1968092_-\|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl\|CDD\|181221
NC_018528.1\|WP_014919533.1\|1962169_1962703_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|379233
NC_018528.1\|WP_013855204.1\|1951245_1951488_-\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|179197

Protein	Function_ID	Function_description	E-value
NC_018528.1\|WP_014919523.1\|1946048_1947428_-\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	gnl\|CDD\|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	0
NC_018528.1\|WP_014919527.1\|1953023_1953470_-\|3-hydroxyacyl-ACP-dehydratase-FabZ	gnl\|CDD\|234568	PRK00006, fabZ, 3-hydroxyacyl-ACP dehydratase FabZ.	1.23853e-76
NC_018528.1\|WP_014919525.1\|1950318_1951236_-\|ACP-S-malonyltransferase	gnl\|CDD\|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	4.10709e-79
NC_018528.1\|WP_013855208.1\|1947862_1948333_-\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	gnl\|CDD\|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	1.93289e-43
NC_018528.1\|WP_014919544.1\|1975811_1976591_+\|indole-3-glycerol-phosphate-synthase-TrpC	gnl\|CDD\|234710	PRK00278, trpC, indole-3-glycerol phosphate synthase TrpC.	2.47219e-119
NC_018528.1\|WP_014919526.1\|1951546_1952530_-\|ketoacyl-ACP-synthase-III	gnl\|CDD\|236475	PRK09352, PRK09352, beta-ketoacyl-ACP synthase 3.	3.30903e-156
NC_018528.1\|WP_014564299.1\|1948336_1949566_-\|beta-ketoacyl-ACP-synthase-II	gnl\|CDD\|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
NC_018528.1\|WP_014564300.1\|1949587_1950319_-\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	1.49589e-102
NC_018528.1\|WP_014919531.1\|1958944_1961212_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
NC_018528.1\|WP_014919535.1\|1964212_1965562_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|180907	PRK07251, PRK07251, FAD-containing oxidoreductase.	1.78086e-170
NC_018528.1\|WP_014564315.1\|1956358_1957198_+\|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl\|CDD\|181221	PRK08072, PRK08072, carboxylating nicotinate-nucleotide diphosphorylase.	3.86206e-124
NC_018528.1\|WP_014919539.1\|1971080_1971320_+\|integrase-core-domain-containing-protein	gnl\|CDD\|372570	pfam13333, rve_2, Integrase core domain.	1.0813e-14
NC_018528.1\|WP_014919543.1\|1974789_1975815_+\|anthranilate-phosphoribosyltransferase	gnl\|CDD\|234682	PRK00188, trpD, anthranilate phosphoribosyltransferase; Provisional.	0
NC_018528.1\|WP_014919545.1\|1976593_1977181_+\|phosphoribosylanthranilate-isomerase	gnl\|CDD\|238237	cd00405, PRAI, Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are monomeric, monofunctional and thermolabile, but in some thermophile organisms PRAI is dimeric for reasons of stability and in others it is fused to other components of the tryptophan biosynthesis pathway to form multifunctional enzymes.	4.68825e-60
NC_018528.1\|WP_014919524.1\|1947441_1947858_-\|beta-hydroxyacyl-ACP-dehydratase	gnl\|CDD\|238615	cd01288, FabZ, FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid biosynthesis pathway.	1.46713e-44
NC_018528.1\|WP_014564303.1\|1952526_1952994_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.05206e-16
NC_018528.1\|WP_174225720.1\|1971437_1972694_-\|MFS-transporter	gnl\|CDD\|340911	cd17353, MFS_OFA_like, Oxalate:formate antiporter (OFA) and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of Oxalobacter formigenes oxalate:formate antiporter (OFA or OxlT) and similar proteins. O. formigenes, a commensal found in the gut of animals and humans, plays an important role in clearing dietary oxalate from the intestinal tract, which is carried out by OFA/OxlT, an anion transporter that facilitates the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation. This exchange generates an electrochemical proton gradient and is the source of energy for ATP synthesis in this cell. The OFA-like subfamily belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.81137e-107
NC_018528.1\|WP_014564315.1\|1967252_1968092_-\|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl\|CDD\|181221	PRK08072, PRK08072, carboxylating nicotinate-nucleotide diphosphorylase.	3.86206e-124
NC_018528.1\|WP_014919533.1\|1962169_1962703_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|379233	pfam13518, HTH_28, Helix-turn-helix domain. This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.	6.84311e-07
NC_018528.1\|WP_013855204.1\|1951245_1951488_-\|acyl-carrier-protein	gnl\|CDD\|179197	PRK00982, acpP, acyl carrier protein; Provisional.	2.22825e-16

>NC_018528.1|WP_014919527.1|1953023_1953470_-|3-hydroxyacyl-ACP-dehydratase-FabZ
MSVLDAAEIMDLIPNRYPILFMDKVDELNPGESIICTKNVTINEEFFQGHFPGNPVMPGVLIIESLAQAASILILKTEKYQGKTAYLGAIDSAKFRKVVRPGDVLKLHVTMEKQRDNMGKVKCEAKVEDKVACSAELTFIVPDPKKKI
>NC_018528.1|WP_014564303.1|1952526_1952994_-|MarR-family-transcriptional-regulator
MNAISDEIKEDYNFISDSLVDIYDQIMRIEESEIKKSRFKDITAKELHLVHTIGLHDHKTTSEVARILRLSKGTLTANLNNLERKGYIFRIRNQRDRRIINLVLTSKGRLLYRAHYAFHRKLVEQCLKGFDGSDIKKMKQALMNVEDFIGEVSGR
>NC_018528.1|WP_014919526.1|1951546_1952530_-|ketoacyl-ACP-synthase-III
MKFEDFKIMATASSAPDHVVTNDELATMMDTSDEWITQRTGIKRRRIATEETTSSMCTDVATQLIAQSDLTAKDIDLIAVATMSPDYLTPSVSAMVQGNIGADHAIAFDIDAACSGFVYGLHLVKQMLIANQQKNAILIGGEILSKLLDWSDRSTAVLFGDGAGGVLIRNTAVDKGSFISEDLRTLGNLGQYLTAGQTGNPSPFATDQQPFSPFFKMNGRRVYSFAVKNVPESINDALKQANLTADEVDCFVLHQANQRIVERIADELAVSMAKFPINIDEYGNTAAASEPILLDQLVKQKIIKRGDVIALSGFGGGLTVGTMIMKY
>NC_018528.1|WP_013855204.1|1951245_1951488_-|acyl-carrier-protein
MTKEEVFNKIKDIIVDQLDVDADKVKENTNFKNDLDLDSLDIFEVIDKIEDLYDIEIDTDEGMETVGELVDYVLKQKTDK
>NC_018528.1|WP_014919525.1|1950318_1951236_-|ACP-S-malonyltransferase
MKLGYLFSGQGKQFDEMGQDLYQQEPVYRQTIDQASEALNMDMSDATVFDNPVNTQVAIVAMSTGIERIINQDFGDPVGATGLSLGEYSAIVAAKGLDFSDALQLVRDRSHYMDQAGQDHPGKMAAVLKTTADMVDQAVKVGSKKGEIYAANYNTDSQIVIGGSIEGLQAATDYLHEHGVKRVVPLKMTVASHTPFMQEASDLLAKRIQDVSFNQLAFPVISNTTSQPFEVNTIKQTLIDQLINPTHFYNCIQQLTQLGVDTVVELGPGDTLMKFAKNVVANDHTFHIDSVKTLNDFRSKAKLVK
>NC_018528.1|WP_014564300.1|1949587_1950319_-|3-oxoacyl-ACP-reductase-FabG
MSDTKQVALVTGAAKGIGLAIAKRLSSDGMTVVINSHHTLTDEEKQSFSDAGFSFDNLVGDVANEADAEKIVGEVVEKYGQIDVLVNNAGITKDKLLSRLKLADFKAVIDTNLVGAFNMTKFAMKFMQKSRSGAIVNLSSISGLHGNLGQANYSASKAGLVGLTKTAAREGALRNIRCNAVAPGMVATDMTGKMSERRQKEFTDQIPLKRFAEPDEIADAVAFLIHNQYITGQVVTVDGGLTI
>NC_018528.1|WP_014564299.1|1948336_1949566_-|beta-ketoacyl-ACP-synthase-II
MSRVVITGMGIVSPIGNDVESFLKNLFASKVGINPITKFDAEPTGITVAGEVKDFDPLKRVDKKFAKRNDLFCTYALYSAKEAMEMAGLTEDNIDPEDLGVIYGSGIGGLTTIQEQVIKMHDKSPKRVSPLFVPDSIINMAAGNISIAFNALNTSQGIVTACSSGTNAIGNAFEYIKQGKAKAIIAGGTEASVNEIGISGFAALTALSKETDPKKASIPFDKDRNGFVLGEGSGTVILEDYDHAKARHANILAEIVGYGTTSDAYHMTAPDPEGKGAIRAMQQAVDEAGIDETEVDYINAHGTSTHANDSAESKAIKQVFAKNDHVKVSSTKGMTGHALGAAGAIEAVATIGAIQHNQMPVNVGVVNQDEACDIELVNDDNKKAPVNYAISNSFGFGGHNAVIVFKGCD
>NC_018528.1|WP_013855208.1|1947862_1948333_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein
MNEKEIERLLEKFDQSSLKDFELTQDDFKLKLSKREQNDQVVVQQPTGSKTPVSEVPKSTSANSQPAGEPQQSVKDNVAEIKAPFVGVVYFAPSPDKPVYKKQGDHVEKGEVVCVIEAMKMINEVKSDVTGTISNILVEDGSMVEYDQPIFQVTKG
>NC_018528.1|WP_014919524.1|1947441_1947858_-|beta-hydroxyacyl-ACP-dehydratase
MKTAVNDVIPQRYPFEMIDKFIDVQPGVSASAIKLISINEWFFANQTSSRLAVPRPIMIEAMAQTGVAAILSIPENKGKNVFFGGIKNATFQDDFRPGDKLEFEVVMKKLKRNIGLGHGTIHRDGQSICEADLIFAVE
>NC_018528.1|WP_014919523.1|1946048_1947428_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit
MFKKVLVANRGEIAVQIIRALHDMGITAVAVYSSADKDSLFVHLADEAICIGGPQPSESYLNMAQIISAANLTGCEAIHPGYGFLSENAEFAELCETCHIKFVGPSHELISLMGDKSNAREAMEKAGVPVIPGSQGVVKTVSQAETVAEKIGFPVLLKAAAGGGGKGIREVDRPEDLHSAFEQTQQEARVSFNNDDIYVEKLIRNAKHVEMQVIADEFNHVVYLPERDCSLQRNHQKVIEESPCVQISPTERKKLGEIVANATLKLGYTNTGTYEFLMTEDHHFYFMEMNTRLQVEHTITEEVTGIELVKAQLKVADGQELPFTQADVAVKGHALECRLNAEDPSHNFAPRPGRINHLFFPAGSLGVRIDSGVAQGSFISPFYDSMIAKVVVHLNDRNTVIAKMNRILEELKINGVVTNQTFLKYLINTAEFNSGQYSTNFIENQVLTNKEGFHVAESV
>NC_018528.1|WP_014564315.1|1956358_1957198_+|carboxylating-nicotinate-nucleotide-diphosphorylase
MNPIVLKEKISEFLKEDLGFGDLSVAFLPGGTPLSGSFIAKQSGIICGQEIPQATYDLLGHATYKPRIPDGAPVKAGDIIGTVSGTAQTLLSGERVTLNLIQRMSGIATQTTHFVKLLDDATIRITDTRKTAPGLRLFDKYAVSVGGGFNHRFDLTGGIMLKDNHIALAGGVTQALAAVKRHVGPLTPVEVEVETEEELRQAVAGGANVIMFDNQNPETIKQWRQLVPKTIKVEASGGITAESISTFKGCGADFISIGNLTNDVTPLDISFLVAGAVKS
>NC_018528.1|WP_014919531.1|1958944_1961212_+|excinuclease-ABC-subunit-UvrA
MTDLFADGTISIHGAQENNLKDVSLDIPKHKTTVFAGLSGSGKSSLVFDTLAAVSRRELNETFPSFTQQYLPKYGQPEVNRIDNLPVAIVVEQKPIGRNSRSTLATYTGIYSVLRLMFSRIGQPWVGYSEWFSFNLPQGMCPKCQGLGFVDDIDERQLIDPNKSLNEGAMTFAGFQPGTWRWKEYGNSGLFDLDKKIKDYTDEEYDLFMHAPQQKLKNPPANWGRTALYEGLVPRMLRSVIHSASGRHHEAALSKIVTRKPCPVCHGTRLNKKALTGKIAGKNIAEVSDMDLVSVLKFLDNISDPKAKTMVRELRSKIQALVDIGLGYLSLGRGTDTLSGGEAQRIKIAKYLTSSLSDLVYVLDEPSVGLHPHDIKLITQSLKKLKEHGNTIILVDHNPAIISTADYVVEMGPQAGKNGGQVTSTGTYDELLRSDTITGKMLREKITFPKPREPQSWLNVNHVTSHNLKDVSTRIPQGVMTVISGPAGSGKSTLVQAFKQQVSDQDYIDLSQDSVGLNIRSTPATYLNILNPLRKLFSKANNGVSTQLFSYNGKGACPRCKGKGVMITEMAFMDPIVQECELCHGKRYSQEALQYTYHGKDISEVLNLSINDTLEFFKDVPDIYKKVSLLHQVGLGYLNLSQSMTTLSGGEVQRVKLAMELNHTGRIYFLDEPTTGLHLQDTQQLIDLFEGLVDKGNTLILIEHNLKLISRADWLVDMGPDAGKFGGQVCFEGHPKDSLNDKNSRTGAALAAIIS
>NC_018528.1|WP_014919533.1|1962169_1962703_-|helix-turn-helix-domain-containing-protein
MVKYSSELKAEVVSEYLQGDISISLLSKKRNLPRIQVGRWIQNFRLSGADALKRRRVKRSFSVEFKVDVINYYQTHDETLAEVSAKFDVNSCQISLWRTAFNEYGIEALKPHPKGRKTKVKHNKKKLRKLVNKNEIDQLREELTKKNQELYDAKLENEILKKSMTLFGTSKDERKHK
>NC_018528.1|WP_014919535.1|1964212_1965562_+|FAD-dependent-oxidoreductase
MDKFKNIIIGFGKAGKTLAKYLAQHDEPVLLIERSKQMYGGTCINVGCLPSKNLILNGQRGLDFTTAVNKRGEMTRQLRDKNYHMVADEPLATIWDGSARFIDNHVLAVEMSDGTTKKVRGERIFINTGAVSNWPSIPGLEFGQRIFTSKEAMELEKQPKRLAIIGGGYIGLEFAGMFNSFGTHVTIFDQHTRLLEREDPDIATEVVADLTDAGIEIKSATQLTQVKDNGEKVTLYYQQGDQSNTAKFDAVLVAVGRRPNINSLGLENTDIALTSRGAIQVDDHLRTTVQNVWALGDVNGGPMFTYVSLDDFRIIVDQLFDKGDRSTADRMVIPTASFLNPPLANVGLNERQAKSAGYDLQTFKLSVKAIPKARVLEDQRGLYKVSVDQKTHLILGATLYAAEAHETINLIALAMKAKLPYERLRDMIYTHPTMSEALNDLFKTPVVKS
>NC_018528.1|WP_014564315.1|1967252_1968092_-|carboxylating-nicotinate-nucleotide-diphosphorylase
MNPIVLKEKISEFLKEDLGFGDLSVAFLPGGTPLSGSFIAKQSGIICGQEIPQATYDLLGHATYKPRIPDGAPVKAGDIIGTVSGTAQTLLSGERVTLNLIQRMSGIATQTTHFVKLLDDATIRITDTRKTAPGLRLFDKYAVSVGGGFNHRFDLTGGIMLKDNHIALAGGVTQALAAVKRHVGPLTPVEVEVETEEELRQAVAGGANVIMFDNQNPETIKQWRQLVPKTIKVEASGGITAESISTFKGCGADFISIGNLTNDVTPLDISFLVAGAVKS
>NC_018528.1|WP_014919539.1|1971080_1971320_+|integrase-core-domain-containing-protein
MVAAELEAWLAADCVELAEEAALFHLLKTECLNGFPQCKDIGEFKEITKNYVDWFNNRRISQKTKGMTPCEYREHALAV
>NC_018528.1|WP_174225720.1|1971437_1972694_-|MFS-transporter
MEELVLKTNRYVVAFAGVMFHLMIGSVYAWSVFTNPIAKQNGWAESSVALAFSIAIFFLGMSAAFMGKVVEKIGPRLTGTIASFLYGTGTIMTGWAIHQNSIWLLYLSYGVIGGLGLGAGYVTPVSTIIKWFPDKRGLATGLAIMGFGFAAMLTGPVAQQLMASVGLEQTFYLLGTFYFVIMLLAAQFIVRPNLALSSTTENSISQKRGTRLTRGPELTANQALKTRSFTFLWIMFFINITCGIGLVSAASPMAQSMTGMSVQTAAIMVGIIGLFNGFGRLIWAALSDYIGRPATFSAIFILDIVMLSAMLIFKLPLLFAIALCLVMSCYGAGFSVIPAYLGDVFGTKELGAIHGYVLTAWAAAGVVGPLLLSLTHQLFHNYTLTLAAFILIDLLALLISFWIQRDFIKASKLIKSKS
>NC_018528.1|WP_014919543.1|1974789_1975815_+|anthranilate-phosphoribosyltransferase
MIKQAIEKVVNHENLTFEESQAVLDEIMNGEASEVQTASLLTALTAKNPTIDEIAGAAASMRSHALAFPETNDVLEIVGTGGDHANTFNISTTSAIVVAATGTKVAKHGNRAASSKSGAADVLEALGLDINETPAVSYQSLKENNLAFLFAQEYHKSMKYVAPVRKQLGFRTIFNILGPLANPAHPTRQLLGVYDESLLEPLANVLKKLGVKKAMVIHGRDGLDEMTTADETAVVELRDGKLTCYTLTPEQFGFNRSQRDELVGGTPEDNGKITRDILSGKKGPKRDIVLLNAGSALHLAHPELSIQAGIDLAAKTIDDGKALEELNRLLAFSNKRKDVVA
>NC_018528.1|WP_014919544.1|1975811_1976591_+|indole-3-glycerol-phosphate-synthase-TrpC
MILDDLVTVTKKRLIRHQKRHSLTELKREVAAMPATTKPNFLSILKQPGLHIISEVKKASPSKGTIVTDFPYLKIAKAYDQAGADAISVLTEPDYFNGHLHYLKDISQAVSVPTLRKDFTIDPYMIYEAKANGAGIILLIVAILDNQQLIAYRELAEQLGMQAIVEAYTADEVTQALKSGAKIIGINNRNLKDFKVDFNNSLKLRAMVPQTIPVVAESGIKTKQDVKKLAAANFNAILMGETLMRSDQKKQLIETFKEV
>NC_018528.1|WP_014919545.1|1976593_1977181_+|phosphoribosylanthranilate-isomerase
MVKVKICGLMKPADVLAVNAADADFAGFVFAPSRHQVSLETALALKMLLMPGIKAVGVFVNESADDILAAYKAGAIDIAQLHGKSMPTEITRLQQAGLQVIQVFERQSIDLTSTADYLMVDSGKGSGRLLNLKAIPHIDRPLILAGGLTSENIAQAVQIVRPDIVDVSSGVETAGHKDASKITRFIKKVKEEILL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_018528_1	1.4\|581008\|34\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581008-581041	34	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	185122-185155	7	0.794
NC_018528_1	1.4\|581008\|34\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581008-581041	34	KY984068	Erwinia phage vB_EamM_Y3, complete genome	54331-54364	7	0.794
NC_018528_1	1.7\|581208\|35\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581208-581242	35	MH791414	UNVERIFIED: Aeromonas phage Aswh_1, complete genome	66400-66434	7	0.8
NC_018528_1	1.7\|581208\|35\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581208-581242	35	NZ_CP014003	Synechococcus sp. PCC 73109 plasmid unnamed5, complete sequence	162722-162756	8	0.771
NC_018528_1	1.13\|581609\|34\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581609-581642	34	AP014404	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C28-MedDCM-OCT-S28-C155, * SEQUENCING IN PROGRESS *, 3 ordered pieces	1499-1532	8	0.765
NC_018528_1	1.6\|581141\|35\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581141-581175	35	CP022016	Salmonella enterica subsp. enterica serovar India str. SA20085604 plasmid unnamed1, complete sequence	347087-347121	9	0.743
NC_018528_1	1.7\|581208\|35\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581208-581242	35	KC330683	Bacillus phage Finn, complete genome	48058-48092	9	0.743
NC_018528_1	1.7\|581208\|35\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581208-581242	35	NC_022765	Bacillus phage Riggi, complete genome	47777-47811	9	0.743
NC_018528_1	1.7\|581208\|35\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581208-581242	35	MT422786	Bacillus phage Novomoskovsk, complete genome	47051-47085	9	0.743
NC_018528_1	1.8\|581275\|35\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581275-581309	35	NZ_CP023678	Zymomonas mobilis subsp. mobilis strain ZM4 substr. 2032 plasmid pZM32, complete sequence	8876-8910	11	0.686
NC_018528_1	1.8\|581275\|35\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581275-581309	35	CP036466	Zymomonas mobilis strain ER79ag plasmid pER79ag32, complete sequence	8876-8910	11	0.686
NC_018528_1	1.8\|581275\|35\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581275-581309	35	CP036462	Zymomonas mobilis strain ZM4* plasmid pZM32o, complete sequence	8878-8912	11	0.686
NC_018528_1	1.8\|581275\|35\|NC_018528\|PILER-CR,CRISPRCasFinder,CRT	581275-581309	35	CP036458	Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 strain ZM4 plasmid pER79ap32, complete sequence	8876-8910	11	0.686

1. spacer 1.4|581008|34|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 7, identity: 0.794

atcgttatgcaggtattactactgctactaatac	CRISPR spacer
taacttatccagatattactactgctactaataa	Protospacer
    **** ***.********************

2. spacer 1.4|581008|34|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to KY984068 (Erwinia phage vB_EamM_Y3, complete genome) position: , mismatch: 7, identity: 0.794

atcgttatgcaggtattactactgct--actaatac	CRISPR spacer
atcgttatgcaggtgttcctactgatgaactagc--	Protospacer
**************.** ****** *  ****..

3. spacer 1.7|581208|35|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to MH791414 (UNVERIFIED: Aeromonas phage Aswh_1, complete genome) position: , mismatch: 7, identity: 0.8

gaaaggaaatatatatgtcagtcaaa--gttaatggt	CRISPR spacer
aaaaggaaaaatatatgtcaatcaaaagggttatg--	Protospacer
.******** **********.*****  * * ***

4. spacer 1.7|581208|35|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014003 (Synechococcus sp. PCC 73109 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.771

gaaaggaaatatatatgtcagtcaaagttaatggt	CRISPR spacer
gaaacgaaatttatatgtcagtcaaggggaaaagc	Protospacer
**** ***** **************.*  ** .*.

5. spacer 1.13|581609|34|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to AP014404 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C28-MedDCM-OCT-S28-C155, *** SEQUENCING IN PROGRESS ***, 3 ordered pieces) position: , mismatch: 8, identity: 0.765

aagtgaatcgacaggtattgcagatgatgattta	CRISPR spacer
aactgctgaaacatctattgcagatgatgattta	Protospacer
** **    .***  *******************

6. spacer 1.6|581141|35|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to CP022016 (Salmonella enterica subsp. enterica serovar India str. SA20085604 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

aattcattactggcattactccagtcactgcgcca	CRISPR spacer
cgcgcaatactggcaatactccagtcactatggca	Protospacer
 .. ** ******** *************..* **

7. spacer 1.7|581208|35|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to KC330683 (Bacillus phage Finn, complete genome) position: , mismatch: 9, identity: 0.743

gaaaggaaatatatatgtcagtcaaagttaatggt-----	CRISPR spacer
aaaaggaaaaatatatgtcactcaaaa-----ggtaccca	Protospacer
.******** ********** *****.     ***

8. spacer 1.7|581208|35|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to NC_022765 (Bacillus phage Riggi, complete genome) position: , mismatch: 9, identity: 0.743

gaaaggaaatatatatgtcagtcaaagttaatggt-----	CRISPR spacer
aaaaggaaaaatatatgtcactcaaaa-----ggtaccca	Protospacer
.******** ********** *****.     ***

9. spacer 1.7|581208|35|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to MT422786 (Bacillus phage Novomoskovsk, complete genome) position: , mismatch: 9, identity: 0.743

gaaaggaaatatatatgtcagtcaaagttaatggt-----	CRISPR spacer
aaaaggaaaaatatatgtcactcaaaa-----ggtaccca	Protospacer
.******** ********** *****.     ***

10. spacer 1.8|581275|35|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023678 (Zymomonas mobilis subsp. mobilis strain ZM4 substr. 2032 plasmid pZM32, complete sequence) position: , mismatch: 11, identity: 0.686

gattttgttagaaaattaaccgatgattttttaca	CRISPR spacer
ccccatattagaaaagtaatcgatgattttttcgc	Protospacer
  .. *.******** ***.************

11. spacer 1.8|581275|35|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to CP036466 (Zymomonas mobilis strain ER79ag plasmid pER79ag32, complete sequence) position: , mismatch: 11, identity: 0.686

gattttgttagaaaattaaccgatgattttttaca	CRISPR spacer
ccccatattagaaaagtaatcgatgattttttcgc	Protospacer
  .. *.******** ***.************

12. spacer 1.8|581275|35|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to CP036462 (Zymomonas mobilis strain ZM4* plasmid pZM32o, complete sequence) position: , mismatch: 11, identity: 0.686

gattttgttagaaaattaaccgatgattttttaca	CRISPR spacer
ccccatattagaaaagtaatcgatgattttttcgc	Protospacer
  .. *.******** ***.************

13. spacer 1.8|581275|35|NC_018528|PILER-CR,CRISPRCasFinder,CRT matches to CP036458 (Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 strain ZM4 plasmid pER79ap32, complete sequence) position: , mismatch: 11, identity: 0.686

gattttgttagaaaattaaccgatgattttttaca	CRISPR spacer
ccccatattagaaaagtaatcgatgattttttcgc	Protospacer
  .. *.******** ***.************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

34492 : 105819

Streptococcus_phage(12.5%)

protease,bacteriocin,integrase,transposase

attL 26204:26218|attR 113841:113855

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
26204:26218	attL	NA	NA	NA	NA
WP_014918011.1\|34492_35692_+\|integrase	tyrosine-type recombinase/integrase	A0A1Q1PVS7	Staphylococcus_phage	1.0e-09	31.6
WP_014918012.1\|36106_37393_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	8.2e-106	51.1
WP_014918013.1\|37649_38003_-	DUF3278 domain-containing protein	NA	NA	NA	NA
WP_003624837.1\|37999_38200_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_014918014.1\|38367_39006_+	ATP-binding cassette domain-containing protein	F2Y302	Organic_Lake_phycodnavirus	2.2e-19	31.8
WP_014918015.1\|39002_39761_+	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_014918016.1\|40782_42042_+	Sir2 silent information regulator family NAD-dependent deacetylase	NA	NA	NA	NA
WP_051001671.1\|42087_42627_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_014918018.1\|42730_44023_+	restriction endonuclease	NA	NA	NA	NA
WP_014918021.1\|45275_45746_+\|transposase	transposase	Q5ULQ4	Lactobacillus_virus	2.4e-31	48.0
WP_014918022.1\|45761_46238_+\|transposase	transposase	Q5ULQ4	Lactobacillus_virus	1.7e-56	69.2
WP_014562800.1\|47115_48516_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_014562801.1\|48612_49386_+	putative ABC transporter permease	NA	NA	NA	NA
WP_014918025.1\|49424_49985_-	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_014562803.1\|49985_50510_-	ECF transporter S component	NA	NA	NA	NA
WP_014562804.1\|50511_50904_-	DUF4430 domain-containing protein	NA	NA	NA	NA
WP_014918026.1\|50921_53156_-	ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent	A0A222ZQ84	Mycobacterium_phage	2.5e-89	33.2
WP_014918027.1\|53410_54445_+	AI-2E family transporter	NA	NA	NA	NA
WP_014918028.1\|54441_55014_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_162470548.1\|55180_55363_+	hypothetical protein	NA	NA	NA	NA
WP_014918029.1\|55431_55770_-	hypothetical protein	NA	NA	NA	NA
WP_014918030.1\|56027_56789_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	5.0e-18	29.8
WP_014918031.1\|56785_57682_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_014918032.1\|57678_58671_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014918033.1\|59009_59717_+	noncanonical pyrimidine nucleotidase, YjjG family	NA	NA	NA	NA
WP_107775352.1\|59773_61240_+	TetM/TetW/TetO/TetS family tetracycline resistance ribosomal protection protein	NA	NA	NA	NA
WP_014918035.1\|61365_62187_+	HAD family hydrolase	NA	NA	NA	NA
WP_014918037.1\|62621_62906_+	hypothetical protein	NA	NA	NA	NA
WP_014918038.1\|62964_63978_-	D-2-hydroxyacid dehydrogenase	M1H502	Paramecium_bursaria_Chlorella_virus	1.3e-50	35.6
WP_014918039.1\|64104_64947_+	fructosamine kinase family protein	NA	NA	NA	NA
WP_014918040.1\|65295_66123_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	2.6e-97	63.5
WP_014918041.1\|67683_70515_+	DEAD/DEAH box helicase	A0A0K2CZF8	Paenibacillus_phage	1.2e-29	24.9
WP_014918042.1\|70554_71565_-	serine hydrolase	NA	NA	NA	NA
WP_014918043.1\|71860_72274_+	peptide deformylase	A0A142EZU8	Stenotrophomonas_phage	6.9e-06	39.4
WP_138427588.1\|77685_77994_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_014918046.1\|79069_79699_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_080588337.1\|79873_80701_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_014918048.1\|81027_81897_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_014918049.1\|81893_82841_-	glycosyltransferase family 8 protein	NA	NA	NA	NA
WP_014918050.1\|82852_83809_-	glycosyltransferase family 8 protein	NA	NA	NA	NA
WP_014918051.1\|83827_84664_-	glycosyl transferase	NA	NA	NA	NA
WP_014918052.1\|84765_85524_-	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_014918054.1\|85986_86718_-	SLAP domain-containing protein	NA	NA	NA	NA
WP_014918055.1\|87247_87469_-	hypothetical protein	NA	NA	NA	NA
WP_014918056.1\|87797_88514_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.3e-40	38.3
WP_041808893.1\|88580_90437_+	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	2.3e-32	31.6
WP_014918058.1\|90426_91776_+	hypothetical protein	NA	NA	NA	NA
WP_014918059.1\|91778_92603_+	two-component system regulatory protein YycI	NA	NA	NA	NA
WP_014918060.1\|92618_93416_+	MBL fold metallo-hydrolase	A0A2I7SDH3	Paenibacillus_phage	2.0e-30	34.1
WP_014918061.1\|93502_94744_+	trypsin-like peptidase domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	1.1e-17	29.4
WP_014918062.1\|95222_95702_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_014918064.1\|97574_98453_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_014918065.1\|98595_99573_+\|bacteriocin	class III bacteriocin	NA	NA	NA	NA
WP_014918066.1\|99655_100747_+	SLAP domain-containing protein	NA	NA	NA	NA
WP_014918067.1\|100875_101760_-	proline iminopeptidase-family hydrolase	NA	NA	NA	NA
WP_014918068.1\|101768_102422_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_041808618.1\|102425_103775_-	ABC transporter ATP-binding protein	A0A1V0SI78	Klosneuvirus	1.1e-10	21.1
WP_014562851.1\|103947_104889_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014918070.1\|104922_105819_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
113841:113855	attR	NA	NA	NA	NA

DBSCAN-SWA_2

560422 : 569189

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014563196.1\|560422_560908_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	2.8e-22	46.4
WP_014918431.1\|560873_562049_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_014918432.1\|562252_562969_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	3.7e-39	38.3
WP_014918433.1\|562969_563224_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_014918434.1\|563220_563892_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_014918435.1\|563888_566117_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.3e-143	39.7
WP_014918436.1\|566092_567544_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.3e-61	34.4
WP_014918437.1\|567545_568583_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.5e-60	41.2
WP_014918438.1\|568592_569189_+	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	3.3e-25	35.7

DBSCAN-SWA_3

815248 : 823700

uncultured_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014918614.1\|815248_815908_+	uracil-DNA glycosylase	A0A218MKQ4	uncultured_virus	3.1e-08	30.4
WP_014918615.1\|815900_816701_+	SGNH/GDSL hydrolase family protein	Q6SEC0	Lactobacillus_prophage	9.3e-07	23.9
WP_014918616.1\|816715_817342_-	transcriptional repressor LexA	A0A1B2APZ1	Phage_Wrath	8.9e-13	53.6
WP_014918617.1\|817492_817756_+	DUF896 domain-containing protein	NA	NA	NA	NA
WP_012212011.1\|817818_818037_+	YneF family protein	NA	NA	NA	NA
WP_014918618.1\|818118_819876_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	7.7e-46	26.6
WP_014918619.1\|819868_821662_+	ABC transporter ATP-binding protein	A0A076FI99	Aureococcus_anophage	5.3e-18	24.3
WP_014918620.1\|821756_823700_+	M13 family metallopeptidase	E3T4I7	Cafeteria_roenbergensis_virus	2.7e-60	28.4

DBSCAN-SWA_4

1791850 : 1855830

Clostridioides_phage(14.29%)

bacteriocin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014919390.1\|1791850_1793128_+\|transposase	ISL3 family transposase	A0A2D1GQC1	Lysinibacillus_phage	8.4e-10	21.7
WP_014919391.1\|1793175_1793607_-	glycosyl transferase family protein	NA	NA	NA	NA
WP_014919392.1\|1793816_1794587_-	DUF4422 domain-containing protein	NA	NA	NA	NA
WP_051001685.1\|1794579_1794795_-	hypothetical protein	NA	NA	NA	NA
WP_014919394.1\|1796447_1796684_-	transferase	A0A191KBJ5	Streptococcus_virus	3.7e-20	65.3
WP_014919395.1\|1796888_1798340_-	flippase	NA	NA	NA	NA
WP_014919396.1\|1798336_1799467_-	hypothetical protein	NA	NA	NA	NA
WP_158310017.1\|1799484_1799640_-	hypothetical protein	NA	NA	NA	NA
WP_014919397.1\|1799702_1800197_-	acyltransferase	NA	NA	NA	NA
WP_014919398.1\|1800193_1800721_-	glycosyltransferase in exopolysaccharide biosynthesis	A0A1V0SGD8	Hokovirus	1.6e-07	31.4
WP_014919399.1\|1800705_1800921_-	lipase chaperone	NA	NA	NA	NA
WP_014919400.1\|1800921_1801947_-	glycosyltransferase family 2 protein	A0A1V0S9B9	Catovirus	7.0e-07	26.8
WP_041808829.1\|1801933_1803037_-	glycosyltransferase	NA	NA	NA	NA
WP_051001686.1\|1803042_1803597_-	hypothetical protein	NA	NA	NA	NA
WP_051001687.1\|1803614_1805006_-	hypothetical protein	NA	NA	NA	NA
WP_014919402.1\|1805014_1805515_-	multidrug MFS transporter	NA	NA	NA	NA
WP_014919403.1\|1805527_1805977_-	UDP-N-acetylglucosamine--LPS N-acetylglucosamine transferase	NA	NA	NA	NA
WP_014919404.1\|1805991_1806642_-	sugar transferase	NA	NA	NA	NA
WP_014919405.1\|1806760_1807531_-	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_014919406.1\|1807530_1808325_-	CpsD/CapB family tyrosine-protein kinase	NA	NA	NA	NA
WP_014919407.1\|1808335_1809223_-	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_012212250.1\|1809234_1810296_-	LCP family protein	A0A1X9I5X1	Streptococcus_phage	2.5e-15	31.1
WP_014919408.1\|1810776_1812042_+	GTPase HflX	NA	NA	NA	NA
WP_014919411.1\|1813279_1814212_-	C40 family peptidase	M9MUG9	Rhodococcus_phage	2.0e-13	36.9
WP_023061786.1\|1814361_1814607_-	hypothetical protein	NA	NA	NA	NA
WP_014919414.1\|1815856_1816753_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_014919415.1\|1816740_1818405_+	ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	4.0e-20	23.6
WP_014919416.1\|1818412_1819123_+	ECF transporter S component	NA	NA	NA	NA
WP_014919417.1\|1820532_1820898_-	hypothetical protein	NA	NA	NA	NA
WP_014919418.1\|1821154_1821904_-	DUF4430 domain-containing protein	NA	NA	NA	NA
WP_014919419.1\|1821938_1822985_-	hypothetical protein	NA	NA	NA	NA
WP_014919420.1\|1823072_1825490_-	DUF4430 domain-containing protein	NA	NA	NA	NA
WP_014919425.1\|1828033_1829377_-	PFL family protein	NA	NA	NA	NA
WP_014919426.1\|1829389_1829659_-	ACT domain-containing protein	NA	NA	NA	NA
WP_014919428.1\|1830696_1831473_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.3e-18	47.2
WP_051001688.1\|1832389_1833973_-\|transposase	transposase	NA	NA	NA	NA
WP_014919431.1\|1833905_1834556_-\|transposase	IS607 family transposase	A0A7Q0	Microcystis_virus	5.2e-40	45.2
WP_023062121.1\|1834621_1834942_-	hypothetical protein	NA	NA	NA	NA
WP_023192438.1\|1834989_1835199_-	Protein of unknown function	NA	NA	NA	NA
WP_014919432.1\|1835293_1836469_-\|transposase	transposase	Q5ULQ4	Lactobacillus_virus	1.0e-123	58.5
WP_003627295.1\|1836597_1836867_-	hypothetical protein	NA	NA	NA	NA
WP_014919433.1\|1836960_1837512_-	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	3.3e-19	45.2
WP_014919434.1\|1837703_1838249_-	AAA family ATPase	A0A0K2FM14	Brevibacillus_phage	1.6e-10	29.4
WP_014919435.1\|1838343_1838643_+	DUF2187 domain-containing protein	NA	NA	NA	NA
WP_014919436.1\|1838735_1840250_+	O-antigen ligase family protein	NA	NA	NA	NA
WP_148271901.1\|1840326_1841556_-\|transposase	transposase	Q5ULQ4	Lactobacillus_virus	4.6e-122	57.7
WP_014919438.1\|1841696_1842320_-	hypothetical protein	NA	NA	NA	NA
WP_014919439.1\|1842337_1842862_-	hypothetical protein	NA	NA	NA	NA
WP_041808833.1\|1844493_1845243_+	C39 family peptidase	NA	NA	NA	NA
WP_014919443.1\|1846832_1847318_-	threonine/serine exporter family protein	NA	NA	NA	NA
WP_014564215.1\|1847320_1848091_-	threonine/serine exporter family protein	NA	NA	NA	NA
WP_014919444.1\|1848101_1849643_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1V0SKJ1	Klosneuvirus	1.4e-43	28.9
WP_014919445.1\|1849651_1850029_-	hypothetical protein	NA	NA	NA	NA
WP_014919446.1\|1850162_1850720_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_014919447.1\|1851477_1852719_-	LCP family protein	NA	NA	NA	NA
WP_014919448.1\|1852880_1854677_+	oligoendopeptidase F	NA	NA	NA	NA
WP_041808836.1\|1854680_1854944_+	hypothetical protein	NA	NA	NA	NA
WP_014919449.1\|1855557_1855830_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA

DBSCAN-SWA_5

1905719 : 1981828

Acinetobacter_phage(30.77%)

integrase,bacteriocin,transposase

attL 1958825:1958882|attR 1994065:1994122

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014919494.1\|1905719_1906523_+\|transposase	transposase	Q5ULQ4	Lactobacillus_virus	4.2e-84	59.4
WP_014919495.1\|1906873_1908082_+	L,D-transpeptidase	NA	NA	NA	NA
WP_014564267.1\|1908171_1908366_+	hypothetical protein	NA	NA	NA	NA
WP_014564268.1\|1908404_1909898_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	9.0e-72	34.7
WP_014564269.1\|1910007_1912542_-	M1 family metallopeptidase	A0A0P0IY26	Acinetobacter_phage	2.0e-71	26.3
WP_014919496.1\|1912748_1913108_+	hypothetical protein	A0A0E3XCL7	Enterococcus_phage	1.5e-20	67.1
WP_014919497.1\|1913170_1914151_-	hypothetical protein	NA	NA	NA	NA
WP_014919498.1\|1914300_1915548_+	MFS transporter	NA	NA	NA	NA
WP_014919503.1\|1917614_1918889_+	MFS transporter	NA	NA	NA	NA
WP_051001690.1\|1919000_1919873_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_014919508.1\|1922283_1922832_+	hypothetical protein	NA	NA	NA	NA
WP_014919511.1\|1924745_1925015_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_014919512.1\|1925090_1927259_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A0D3MSW9	Lactococcus_phage	1.9e-171	47.5
WP_005720082.1\|1927251_1927677_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	J9PTY0	Bacillus_phage	1.1e-11	38.3
WP_014919513.1\|1927657_1928665_-	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A160DHK0	Gordonia_phage	3.5e-96	53.7
WP_003618609.1\|1932311_1932785_+	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_014564286.1\|1932938_1935224_+	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
WP_014919517.1\|1935201_1936134_+	methylenetetrahydrofolate reductase [NAD(P)H]	NA	NA	NA	NA
WP_014564289.1\|1937504_1938539_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	1.5e-36	32.0
WP_014564290.1\|1938754_1939831_+	guanine permease	NA	NA	NA	NA
WP_014564291.1\|1939833_1940391_+	adenine phosphoribosyltransferase	NA	NA	NA	NA
WP_014919521.1\|1941992_1942535_-	biotin transporter BioY	NA	NA	NA	NA
WP_003630368.1\|1942608_1943598_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_003630369.1\|1943645_1944404_-	enoyl-ACP reductase FabI	NA	NA	NA	NA
WP_014919522.1\|1944462_1945233_-	acetyl-CoA carboxylase carboxyl transferase subunit alpha	NA	NA	NA	NA
WP_014564296.1\|1945225_1946068_-	acetyl-CoA carboxylase carboxyltransferase subunit beta	NA	NA	NA	NA
WP_014919523.1\|1946048_1947428_-	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_014919524.1\|1947441_1947858_-	beta-hydroxyacyl-ACP dehydratase	NA	NA	NA	NA
WP_013855208.1\|1947862_1948333_-	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_014564299.1\|1948336_1949566_-	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_014564300.1\|1949587_1950319_-	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	1.8e-12	29.6
WP_014919525.1\|1950318_1951236_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_013855204.1\|1951245_1951488_-	acyl carrier protein	NA	NA	NA	NA
WP_014919526.1\|1951546_1952530_-	ketoacyl-ACP synthase III	NA	NA	NA	NA
WP_014564303.1\|1952526_1952994_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_014919527.1\|1953023_1953470_-	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_014564315.1\|1956358_1957198_+	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
1958825:1958882	attL	NA	NA	NA	NA
WP_014919531.1\|1958944_1961212_+	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.5e-126	30.9
WP_014919533.1\|1962169_1962703_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_014919535.1\|1964212_1965562_+	FAD-dependent oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.9e-121	49.4
WP_014564315.1\|1967252_1968092_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_014919539.1\|1971080_1971320_+\|integrase	integrase core domain-containing protein	NA	NA	NA	NA
WP_174225720.1\|1971437_1972694_-	MFS transporter	NA	NA	NA	NA
WP_014919543.1\|1974789_1975815_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	2.9e-61	38.9
WP_014919544.1\|1975811_1976591_+	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	1.7e-37	37.8
WP_014919545.1\|1976593_1977181_+	phosphoribosylanthranilate isomerase	NA	NA	NA	NA
WP_014919546.1\|1977177_1978398_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_014919547.1\|1978390_1979185_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_107775355.1\|1979560_1980955_-\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_014919549.1\|1980970_1981828_-\|transposase	IS982 family transposase	NA	NA	NA	NA
1994065:1994122	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_018528

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection