CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017448	Fibrobacter succinogenes subsp. succinogenes S85, complete sequence	15 crisprs	DEDDh,cas9,cas1,cas2,csa3,WYL,cas3,RT,PD-DExK,cas6,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20,DinG	3	22	0	0

1. NC_017448

CRISPR-Cas detection and classification

Crispr_ID: NC_017448_1

• CRISPR_ID: NC_017448_1
• CRISPR_location: 612214-614746
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 32 spacers
• Cas_protein_info: cas2,cas1,cas9

Consensus repeat of NC_017448_1

Consensus_repeat	Method
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	PILER-CR
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	CRISPRCasFinder
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	PILER-CR

spacers of NC_017448_1

>1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder
GCATATCTGAATAAACTAAACAACAAAAA
>1.2|612339|30|NC_017448|PILER-CR,CRISPRCasFinder
TATTTTCAGTGTAGGTCATGATTTACCCCA
>1.3|612417|30|NC_017448|PILER-CR,CRISPRCasFinder
TGTAGTTAATACCATTATCGCTAAAATCAA
>1.4|612495|29|NC_017448|PILER-CR,CRISPRCasFinder
AATAATACTTTGCAATTGTCAATAGAAAA
>1.5|612572|30|NC_017448|PILER-CR,CRISPRCasFinder
AGCATTTGGAATTTCTTTGAGTTGTGTTTC
>1.6|612650|30|NC_017448|PILER-CR,CRISPRCasFinder
TAATTTGATTCGCAATTGCACCGCTAGACG
>1.7|612728|30|NC_017448|PILER-CR,CRISPRCasFinder
TAGATATTTTTGACAATTTGGATTGTATCT
>1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder
TTTCTTTTGTGTAGTTCATGGTTTTATCCT
>1.9|612884|30|NC_017448|PILER-CR,CRISPRCasFinder
AGGTCTGCTGGTCTTCCGGGAAGAGCATCT
>1.10|612962|29|NC_017448|CRISPRCasFinder
GGAACGCGCACCGTTTGACGCAAAGAAAG
>1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR
GATGCTCGGCATCTTGCCGAAAGGCCGAAG
>1.12|613117|29|NC_017448|CRISPRCasFinder,PILER-CR
AAAGTTTCTCCCAATAAACGCTACAAAGA
>1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR
GCTGGCCCTCTTGGTGCTATGGCCGCAGGC
>1.14|613272|30|NC_017448|CRISPRCasFinder,PILER-CR
GCAAGTATGGTAATATGTATGACCACGGCG
>1.15|613350|30|NC_017448|CRISPRCasFinder,PILER-CR
AGTATTCGGACTATATCGGGCGGGCTCGTT
>1.16|613428|30|NC_017448|CRISPRCasFinder,PILER-CR
TACAAAGATAGGATGTTGCATATTTATTAA
>1.17|613506|30|NC_017448|CRISPRCasFinder,PILER-CR
TTAATTTCGTCCACACCGTCAAACCTAAAC
>1.18|613584|29|NC_017448|CRISPRCasFinder,PILER-CR
AGAAGAGCGAGTTCACGCCGTTGTGGGTT
>1.19|613661|30|NC_017448|CRISPRCasFinder,PILER-CR
GCTACTGTGCAGTCATTACAAGACCGCGTT
>1.20|613739|29|NC_017448|CRISPRCasFinder,PILER-CR
TGGTGTGAGTCTTGGTTCTCGCTTCGCTC
>1.21|613816|30|NC_017448|CRISPRCasFinder,PILER-CR
GCTACTGTGCAGTCATTACAAGACCGCGTT
>1.22|613894|29|NC_017448|CRISPRCasFinder,PILER-CR
TGGTGTGAGTCTTGGTTCTCGCTTCGCTC
>1.23|613971|30|NC_017448|CRISPRCasFinder,PILER-CR
GATTAACGTTACAATCCTCCACCTTTCCTT
>1.24|614049|29|NC_017448|CRISPRCasFinder,PILER-CR
GGGTTGAGTGGTCCAGCTTGTTATCTACT
>1.25|614126|30|NC_017448|CRISPRCasFinder,PILER-CR
GGGTGGAGGCTTTAATGTCCTTAGATGTTC
>1.26|614204|29|NC_017448|CRISPRCasFinder,PILER-CR
GGAAGGCGATACGGATAAGTTGAACGAAA
>1.27|614281|30|NC_017448|CRISPRCasFinder,PILER-CR
AGTATCATGGCAATATTCTTTCGGGGCATT
>1.28|614359|30|NC_017448|CRISPRCasFinder,PILER-CR
GCTCAGCAGCACGAAATTACTAATAGTCCT
>1.29|614437|29|NC_017448|CRISPRCasFinder,PILER-CR
TATCGACTTGCGACAACGAAGCTCTTGAT
>1.30|614514|30|NC_017448|CRISPRCasFinder,PILER-CR
AATCTGTAAGCACTATTGGAAATATGGTCT
>1.31|614592|30|NC_017448|CRISPRCasFinder,PILER-CR
TGCTTGACGAAGTTGGCAATGAATGGTACA
>1.32|614670|29|NC_017448|CRISPRCasFinder
TAAAATCCCGACGTATGTATTCATCGACG

CRISPR arrays and Neighbor proteins around NC_017448_1

CRISPR arrays

The CRISPR arrays of NC_017448_1

>merge|NC_017448|1|612214-614746|PILER-CR,CRISPRCasFinder,PILER-CR
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGCATATCTGAATAAACTAAACAACAAAAAGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTATTTTCAGTGTAGGTCATGATTTACCCCAGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTGTAGTTAATACCATTATCGCTAAAATCAAGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACAATAATACTTTGCAATTGTCAATAGAAAAGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACAGCATTTGGAATTTCTTTGAGTTGTGTTTCGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTAATTTGATTCGCAATTGCACCGCTAGACGGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTAGATATTTTTGACAATTTGGATTGTATCTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTTTCTTTTGTGTAGTTCATGGTTTTATCCTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACAGGTCTGCTGGTCTTCCGGGAAGAGCATCTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGGAACGCGCACCGTTTGACGCAAAGAAAGGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGATGCTCGGCATCTTGCCGAAAGGCCGAAGGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACAAAGTTTCTCCCAATAAACGCTACAAAGAGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGCTGGCCCTCTTGGTGCTATGGCCGCAGGCGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGCAAGTATGGTAATATGTATGACCACGGCGGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACAGTATTCGGACTATATCGGGCGGGCTCGTTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTACAAAGATAGGATGTTGCATATTTATTAAGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTTAATTTCGTCCACACCGTCAAACCTAAACGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACAGAAGAGCGAGTTCACGCCGTTGTGGGTTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGCTACTGTGCAGTCATTACAAGACCGCGTTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTGGTGTGAGTCTTGGTTCTCGCTTCGCTCGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGCTACTGTGCAGTCATTACAAGACCGCGTTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTGGTGTGAGTCTTGGTTCTCGCTTCGCTCGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGATTAACGTTACAATCCTCCACCTTTCCTTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGGGTTGAGTGGTCCAGCTTGTTATCTACTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGGGTGGAGGCTTTAATGTCCTTAGATGTTCGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGGAAGGCGATACGGATAAGTTGAACGAAAGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACAGTATCATGGCAATATTCTTTCGGGGCATTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGCTCAGCAGCACGAAATTACTAATAGTCCTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTATCGACTTGCGACAACGAAGCTCTTGATGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACAATCTGTAAGCACTATTGGAAATATGGTCTGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTGCTTGACGAAGTTGGCAATGAATGGTACAGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACTAAAATCCCGACGTATGTATTCATCGACGGTTGTTATTGCACTAGTAAAACTAGAAAATCTAAAAGAAGTTGCGCCC

>NC_017448|1|1|612214-612961|PILER-CR
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCATATCTGAATAAACTAAACAACAAAAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TATTTTCAGTGTAGGTCATGATTTACCCCA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGTAGTTAATACCATTATCGCTAAAATCAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AATAATACTTTGCAATTGTCAATAGAAAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGCATTTGGAATTTCTTTGAGTTGTGTTTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TAATTTGATTCGCAATTGCACCGCTAGACG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TAGATATTTTTGACAATTTGGATTGTATCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TTTCTTTTGTGTAGTTCATGGTTTTATCCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGGTCTGCTGGTCTTCCGGGAAGAGCATCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGGAACGCGCACCGTTTGACGCAAAGAAAGGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GATGCTCGGCATCTTGCCGAAAGGCCGAAG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AAAGTTTCTCCCAATAAACGCTACAAAGA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTGGCCCTCTTGGTGCTATGGCCGCAGGC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCAAGTATGGTAATATGTATGACCACGGCG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGTATTCGGACTATATCGGGCGGGCTCGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TACAAAGATAGGATGTTGCATATTTATTAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TTAATTTCGTCCACACCGTCAAACCTAAAC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGAAGAGCGAGTTCACGCCGTTGTGGGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTACTGTGCAGTCATTACAAGACCGCGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGGTGTGAGTCTTGGTTCTCGCTTCGCTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTACTGTGCAGTCATTACAAGACCGCGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGGTGTGAGTCTTGGTTCTCGCTTCGCTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GATTAACGTTACAATCCTCCACCTTTCCTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GGGTTGAGTGGTCCAGCTTGTTATCTACT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GGGTGGAGGCTTTAATGTCCTTAGATGTTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GGAAGGCGATACGGATAAGTTGAACGAAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGTATCATGGCAATATTCTTTCGGGGCATT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTCAGCAGCACGAAATTACTAATAGTCCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TATCGACTTGCGACAACGAAGCTCTTGAT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AATCTGTAAGCACTATTGGAAATATGGTCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGCTTGACGAAGTTGGCAATGAATGGTACA


>NC_017448|1|1|612214-614746|CRISPRCasFinder
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCATATCTGAATAAACTAAACAACAAAAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TATTTTCAGTGTAGGTCATGATTTACCCCA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGTAGTTAATACCATTATCGCTAAAATCAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AATAATACTTTGCAATTGTCAATAGAAAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGCATTTGGAATTTCTTTGAGTTGTGTTTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TAATTTGATTCGCAATTGCACCGCTAGACG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TAGATATTTTTGACAATTTGGATTGTATCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TTTCTTTTGTGTAGTTCATGGTTTTATCCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGGTCTGCTGGTCTTCCGGGAAGAGCATCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GGAACGCGCACCGTTTGACGCAAAGAAAG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GATGCTCGGCATCTTGCCGAAAGGCCGAAG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AAAGTTTCTCCCAATAAACGCTACAAAGA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTGGCCCTCTTGGTGCTATGGCCGCAGGC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCAAGTATGGTAATATGTATGACCACGGCG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGTATTCGGACTATATCGGGCGGGCTCGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TACAAAGATAGGATGTTGCATATTTATTAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TTAATTTCGTCCACACCGTCAAACCTAAAC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGAAGAGCGAGTTCACGCCGTTGTGGGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTACTGTGCAGTCATTACAAGACCGCGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGGTGTGAGTCTTGGTTCTCGCTTCGCTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTACTGTGCAGTCATTACAAGACCGCGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGGTGTGAGTCTTGGTTCTCGCTTCGCTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GATTAACGTTACAATCCTCCACCTTTCCTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GGGTTGAGTGGTCCAGCTTGTTATCTACT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GGGTGGAGGCTTTAATGTCCTTAGATGTTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GGAAGGCGATACGGATAAGTTGAACGAAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGTATCATGGCAATATTCTTTCGGGGCATT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTCAGCAGCACGAAATTACTAATAGTCCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TATCGACTTGCGACAACGAAGCTCTTGAT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AATCTGTAAGCACTATTGGAAATATGGTCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGCTTGACGAAGTTGGCAATGAATGGTACA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TAAAATCCCGACGTATGTATTCATCGACG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTAAAAGAAGTTGCGCCC

>NC_017448|1|2|612991-614669|PILER-CR
	GCATATCTGAATAAACTAAACAACAAAAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TATTTTCAGTGTAGGTCATGATTTACCCCA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGTAGTTAATACCATTATCGCTAAAATCAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AATAATACTTTGCAATTGTCAATAGAAAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGCATTTGGAATTTCTTTGAGTTGTGTTTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TAATTTGATTCGCAATTGCACCGCTAGACG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TAGATATTTTTGACAATTTGGATTGTATCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TTTCTTTTGTGTAGTTCATGGTTTTATCCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGGTCTGCTGGTCTTCCGGGAAGAGCATCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAACGGAACGCGCACCGTTTGACGCAAAGAAAGGTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GATGCTCGGCATCTTGCCGAAAGGCCGAAG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AAAGTTTCTCCCAATAAACGCTACAAAGA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTGGCCCTCTTGGTGCTATGGCCGCAGGC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCAAGTATGGTAATATGTATGACCACGGCG
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGTATTCGGACTATATCGGGCGGGCTCGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TACAAAGATAGGATGTTGCATATTTATTAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TTAATTTCGTCCACACCGTCAAACCTAAAC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGAAGAGCGAGTTCACGCCGTTGTGGGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTACTGTGCAGTCATTACAAGACCGCGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGGTGTGAGTCTTGGTTCTCGCTTCGCTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTACTGTGCAGTCATTACAAGACCGCGTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGGTGTGAGTCTTGGTTCTCGCTTCGCTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GATTAACGTTACAATCCTCCACCTTTCCTT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GGGTTGAGTGGTCCAGCTTGTTATCTACT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GGGTGGAGGCTTTAATGTCCTTAGATGTTC
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GGAAGGCGATACGGATAAGTTGAACGAAA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AGTATCATGGCAATATTCTTTCGGGGCATT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	GCTCAGCAGCACGAAATTACTAATAGTCCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TATCGACTTGCGACAACGAAGCTCTTGAT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	AATCTGTAAGCACTATTGGAAATATGGTCT
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC	TGCTTGACGAAGTTGGCAATGAATGGTACA
GTTGTTATTGCACTAGTAAAACTAGAAAATCTGAAAGCAATTCACAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_012819989.1|617839_618154_+|ferredoxin-family-protein	unknown	unknown	gnl|CDD|224069
NC_017448.1|WP_012819992.1|620970_621990_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_012819979.1|599168_600455_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_012819983.1|604950_605889_-|Rpn-family-recombination-promoting-nuclease/putative-transposase	unknown	unknown	gnl|CDD|372314
NC_017448.1|WP_012819990.1|618164_619064_+|sulfate-adenylyltransferase-subunit-CysD	unknown	unknown	gnl|CDD|235375
NC_017448.1|WP_012819994.1|623276_624110_+|sulfate-ABC-transporter-permease-subunit-CysT	unknown	unknown	gnl|CDD|131194
NC_017448.1|WP_012819984.1|606342_610881_+|CRISPR-associated-protein-Csn1	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|375967
NC_017448.1|WP_012819987.1|615188_616049_+|4Fe-4S-binding-protein	unknown	unknown	gnl|CDD|225131
NC_017448.1|WP_012819985.1|610877_611774_+|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|274694
NC_017448.1|WP_012819986.1|611775_612111_+|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226043
NC_017448.1|WP_012819991.1|619063_620749_+|sulfate-adenylyltransferase	unknown	unknown	gnl|CDD|235349
NC_017448.1|WP_012819981.1|601787_603233_+|anthranilate-synthase-component-I	unknown	unknown	gnl|CDD|273142
NC_017448.1|WP_012819980.1|600703_601444_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_012819996.1|624942_626001_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226361
NC_017448.1|WP_012819988.1|616092_617856_+|adenylyl-sulfate-reductase-subunit-alpha	unknown	unknown	gnl|CDD|235879
NC_017448.1|WP_012819978.1|598383_599154_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_012819982.1|603234_604830_+|bifunctional-anthranilate-synthase-component-II/anthranilate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|237764
NC_017448.1|WP_012819993.1|622101_623121_+|sulfate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224529
NC_017448.1|WP_012819977.1|597389_598367_-|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_012819995.1|624109_624931_+|sulfate-ABC-transporter-permease-subunit-CysW	unknown	unknown	gnl|CDD|226665

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_012819984.1|606342_610881_+|CRISPR-associated-protein-Csn1	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	1.2e-57	190.6	46.0
NC_017448.1|WP_012819985.1|610877_611774_+|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	4.1e-100	329.2	0.0
NC_017448.1|WP_012819986.1|611775_612111_+|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	2.7e-29	96.5	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_012819989.1|617839_618154_+|ferredoxin-family-protein	gnl|CDD|224069	COG1146, COG1146, Ferredoxin [Energy production and conversion].	6.2071e-13
NC_017448.1|WP_012819979.1|599168_600455_-|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	4.09887e-12
NC_017448.1|WP_012819983.1|604950_605889_-|Rpn-family-recombination-promoting-nuclease/putative-transposase	gnl|CDD|372314	pfam12784, PDDEXK_2, PD-(D/E)XK nuclease family transposase. Members of this family belong to the PD-(D/E)XK nuclease superfamily. These proteins are transposase proteins.	2.30048e-30
NC_017448.1|WP_012819990.1|618164_619064_+|sulfate-adenylyltransferase-subunit-CysD	gnl|CDD|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
NC_017448.1|WP_012819994.1|623276_624110_+|sulfate-ABC-transporter-permease-subunit-CysT	gnl|CDD|131194	TIGR02139, permease_CysT, sulfate ABC transporter, permease protein CysT. This model represents CysT, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysW (TIGR02140). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions].	2.21874e-117
NC_017448.1|WP_012819987.1|615188_616049_+|4Fe-4S-binding-protein	gnl|CDD|225131	COG2221, DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Energy production and conversion].	1.21149e-66
NC_017448.1|WP_012819985.1|610877_611774_+|type-II-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	3.26424e-135
NC_017448.1|WP_012819986.1|611775_612111_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.75736e-26
NC_017448.1|WP_012819991.1|619063_620749_+|sulfate-adenylyltransferase	gnl|CDD|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0
NC_017448.1|WP_012819981.1|601787_603233_+|anthranilate-synthase-component-I	gnl|CDD|273142	TIGR00564, Anthranilate_synthase_component_1, anthranilate synthase component I, non-proteobacterial lineages. This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. Archaeal enzymes have been excluded from this model (and are now found in TIGR01820) as have a clade of enzymes which constitute a TrpE paralog which may have PabB activity (TIGR01824). This allows the B. subtilus paralog which has been shown to have PabB activity to score below trusted to this model. This model contains sequences from gram-positive bacteria, certain proteobacteria, cyanobacteria, plants, fungi and assorted other bacteria.A second family of TrpE enzymes is modelled by TIGR00565. The breaking of the TrpE family into these diverse models allows for the separation of the models for the related enzyme, PabB. [Amino acid biosynthesis, Aromatic amino acid family].	3.66793e-163
NC_017448.1|WP_012819984.1|606342_610881_+|CRISPR-associated-protein-Csn1	gnl|CDD|375967	pfam18541, RuvC_III, RuvC endonuclease subdomain 3. Cas9 proteins are abundant across the bacterial kingdom, but vary widely in both sequence and size. All known Cas9 enzymes contain an HNH domain that cleaves the DNA strand complementary to the guide RNA sequence (target strand), and a RuvC nuclease domain required for cleaving the noncomplementary strand (non-target strand), yielding double-strand DNA breaks (DSBs). The crystal structures of type II-A and II-C Cas9 proteins highlight the features in Cas9 enzymes that support their function as RNA-guided endonucleases. Cas9 enzymes adopt a bilobed architecture composed of a nuclease lobe containing juxtaposed RuvC and HNH nuclease domains and a variable alpha-helical lobe likely to be involved in nucleic acid binding. The RuvC domain forms the structural core of the nuclease lobe, a six-stranded beta sheet surrounded by four alpha helices, with all three conserved subdomains (I, II, III) contributing catalytic residues to the active site.	2.84464e-55
NC_017448.1|WP_012819996.1|624942_626001_+|ABC-transporter-ATP-binding-protein	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	4.50273e-135
NC_017448.1|WP_012819988.1|616092_617856_+|adenylyl-sulfate-reductase-subunit-alpha	gnl|CDD|235879	PRK06854, PRK06854, adenylyl-sulfate reductase subunit alpha.	0
NC_017448.1|WP_012819978.1|598383_599154_-|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	8.31478e-19
NC_017448.1|WP_012819982.1|603234_604830_+|bifunctional-anthranilate-synthase-component-II/anthranilate-phosphoribosyltransferase	gnl|CDD|237764	PRK14607, PRK14607, bifunctional anthranilate synthase component II/anthranilate phosphoribosyltransferase.	0
NC_017448.1|WP_012819993.1|622101_623121_+|sulfate-ABC-transporter-substrate-binding-protein	gnl|CDD|224529	COG1613, Sbp, ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism].	2.33396e-177
NC_017448.1|WP_012819977.1|597389_598367_-|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	1.44671e-17
NC_017448.1|WP_012819995.1|624109_624931_+|sulfate-ABC-transporter-permease-subunit-CysW	gnl|CDD|226665	COG4208, CysW, ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism].	2.16375e-122

Protein sequences

>NC_017448.1|WP_012819986.1|611775_612111_+|CRISPR-associated-endonuclease-Cas2
MDRFSEYRIMWILCFFDLPTETKIERQRHSEFRKNLLKDGFSRFQLSIYVRHCASVENAEVHIARVKSFMPPDGSVSILCITDKQFGKIQVFYGRKEKPKPKSTGQLELFL
>NC_017448.1|WP_012819985.1|610877_611774_+|type-II-CRISPR-associated-endonuclease-Cas1
MIKRTLYFGNQAYLSLKDNQLVIKKRNDEIVTAAIEDIAYIVLDSPQITVTNALLGALLENNCAIINCDKTHLPSGLLLPLSGNTLQSERFQAQIDASLPLKKQLWQQTVQQKILNQAAVLHGSHDAEIGNMTAWANSVRSGDVDNREAVAAAYYWKEMFPDIPDFVRDRNGVPPNNMLNYGYAILRGVVARALVSSGLLPTLGIHHHNRYNAYCLADDIMEPYRPIVDKLILEVINEIEEYPTDLSTEIKAKLLRIPVLDCVIDGNRSPLMNAVSTTTASLAKCYLGTTRKLLYPEV
>NC_017448.1|WP_012819984.1|606342_610881_+|CRISPR-associated-protein-Csn1
MKKILGLDLGTNSIGWAVVNADEITRDDGSRYLKPNGISAAGSRIIPMSADILGDFEKGNSISQTAERTRMRMARRLHERALLRRERLLRVLNLLDFLPKHFADKIDRYGKFTDDSEPKLAWRKNTEGKYEFIFQDAFNEMLAEFKDKQPEIVEEGKKIPYDWTIYYLRKKALEKALSKEELSWILLQFNQKRGYYQLRGEEEEIPQDKKIEYLAQKVVKVEATDQKKGDDVWYNVYLENGMIYRRTSKAPLDWEGKVKEFIVTTEVENDGETPKKDKEGNIKRSFRAPKEDDWTLLKKKTEADIENSHKTVGCYIYDSLLNNPKQKIIGKLVRTVERKFYKEELTQILKKQVELIPELRDDNLYKQCIEELYPINEAHRNTIAKTDFANLFINDILFYQRPLKSKKSQIDNCPYEERIFIDSKTGEKKKVPVKCIAKSNPLFQEFRLWQFIQNLRIYQREKEIDGKLLTDIDITSECLKSEEDYVRLFDWLNDRETIEQEDLLKHLFNTKKSKNKENPYRWNYVEDKVYPCNETRATILKGFSKCGINASVLSPELEMALWHILYSVEDKKEIETALTHFAQKQGWNDDFAKVFSKAKPFKKDYGSYSEKAIKKLLSLMRMGKYWNQDNIDKNTLDRIDKIINGEYDEKISNRVRDNAINLKDISDFRGLPVWLACYIVYDRHSEAKDCTKWNSPEEIDSYLKKFKQHSLRNPIVEQVVTETLRTVRDIWIQEEQIDEIHLELGRDLKNPADKRKKMSENILKNENTNLRIKAMLMEFMNPSMGIENVRPYSPSQQDILRIYEENALDNLTKDDKDFDFISKISKQAQPSKTDIIRYKCWLEQKYRSPYTGKTISLSKLFTPAYEIEHVIPQSLYFDDSFSNKVICEAEVNKLKDRQLGYKFIAEHHGEKVQLSQGEVVEILSVDAYEKFVKENYANNRIKMKKLLMESIPDEFIERQLNDSRYISKVVKGLLSNIVREKIDDENYEPEAVSKNLISCNGAITDRLKKDWGMNDVWNSIILPRFIRMNQITGKDCFTTTNAEGHLIPQMPLELQKGFNKKRIDHRHHAMDAIVIACTTRDHVNLLNNEAAHSKFNATRYQLQRKLRRFEKAVIDGKEREVAKEFLKPWDSFSSDSKNILENIIVSFKQNQRVINKTTNAFLHFDENGKKTFIKQGKGDSWAIRKSMHKDTVFGEINLRKVRSVSLNEAIKVPERVLNKKIKEKILELKNNKIDAKNIKKYIEENHTGGYGIDSSKIDVFYFTKETKERFFATRKTLDTSFNQAKIKDSIADSGIQKILLAHLKSKNGDAEQAFSPDGIDEMNKNIVELNNGKFHQPILKVRVYEKADKFAVGQKGNKKVKFVEAAKGTNLFFAIFEKDGKRSYLTIPLNVMIDCQKQYGNQWKNNIEAYLKEKELVEKDVKLQFILSPNDLVYLPTEGSIDKKRIYKVVSFTNNRLYAIPYAIAKSIVDKNEFTQLNKIEFTDNKESIKDACVPVIIDRLGNVIEFNGKRL
>NC_017448.1|WP_012819983.1|604950_605889_-|Rpn-family-recombination-promoting-nuclease/putative-transposase
MNARKSFRDCIVKPGETSPYANLLVDLAFKKAFDPDKPTSRNNLINLLNDLLEPQLKRPIKNVWTRSVAKNLSGSKASRTAIFDLHCKDDLGSLIEIEVQIREVDNFMKRLAFYASEMVANQAEPGQYWDYDIQPTYVIALTRFSVFPDERAVHRATVIDLESGEQLVDTYNFTAIELSKVPFFIEKTSSDLSKWLFFFRYLNRLKELPEELDEGKFKNLTESAKVSNFNKKEFEVYRNMYHKVWDHNAMRRGIFKEFADDINAKIEERISDRNREFAKKMIELGKLSDEEIAATTDLSLEDIVVLRSQLEA
>NC_017448.1|WP_012819982.1|603234_604830_+|bifunctional-anthranilate-synthase-component-II/anthranilate-phosphoribosyltransferase
MIIIIDNYDSFTYNVYQALAKITTEEIRVLRSRECTIADIEKLNPSRLIVSPGPGRPEDAGISVEAIKHFAGKLPILGVCLGHQAIGYAFGAKIVQAKFIKHGIAEEIDLDGKGLFRTIGKKNIFTRYHSLVIDESTLPGDFEVTARATDGDIMGIRHKTLPIEGVQFHPESIASGRADEFFKAFLNYRREPLDIRGILNTLTAGKDLTRETAEMFMEDLTDGIMDERQMAAILTALSSKGPVADEIAGCAKVLSSKKRKFPYSGDELTDIVGTGGDGKGSFNVSSLSGLIAASCGAKIAKHGNRAVSSKSGAADFYTAAGFKLDMTPEKAASVIDKTNFVFLMAPVYHSAMRFAGPVRGALGVKTIMNLLGPLTNPAEAKYLMLGVYSKSILEPFTKAAKFLGAKRVMVAISDDGYDEISPCVPTTIAEILEDGEYREYRIDPKEFGVPAVDPEDLAGGTGVDNFNLALDVLNGKGRPGIKYACALNAGAALYISNKAASIKEGFDKAIKAMEDGSVLKKIEEVKVATNA
>NC_017448.1|WP_012819981.1|601787_603233_+|anthranilate-synthase-component-I
MTKITHITERPGYAPRTDSIYVALPGERYTPFSLAKKLGAKAIFESASFDHGRSRYSTLMVDEGFRLRQNDKNVSIVVDGKESEFLAEGDGDILDALLKISAENTVPPNQIPIPSSGVGYLGYEFCARCDTIRLAPQVDELNIPEAEFLVGHIYIVFDHFTEKLHLFALNYEEHQIDLKAAIEKVKARLADLDFSYLAPEKQYSKGITMTDLEQSRKEYVEKVAALQKHIVAGNIVQAVPSRRIQFASDIEALDIYRRLRTVNPSPYMFFLDYGTHQFIGASPESLIRVREGIATIHPIAGTRRRGKDDAEDEALMKNLKGDPKERAEHLMLVDLARNDLGRVCDAGTVETTKYMECEKFSHVIHLVSDVQGRVSKNKKAIEVLRSSFPAGTVSGAPKISAIEILSGLEKIKRRFYAGAVGYIESDGDLDFCIAIRCCLKQGKTISLQAGGGIVAASNADREFEETNEKLGAIRAVLEGEN
>NC_017448.1|WP_012819980.1|600703_601444_+|hypothetical-protein
MMNTHTTANEVMNLIDLAQHTKNGKEGSDAINKLWDIFGDKVTGITIKKSFSHDSDHSMHGMSVYERRNQLQEQAFDTFRNAVLTYDASTNVPFMAYVSKKINWQQLDFKRKNAKHTHNEKATDFSIEGGSSISMDDPKNAEMLETMNHIDLESPMAGRFVEDFEKQSYLDDMVHVLFGKLQNEKKLLEFATTYYEVCQEEDKDTDAEVAKRMGCTRSYASQLHKKLIAFLSNTDFADDCRMALAA
>NC_017448.1|WP_012819979.1|599168_600455_-|serine/threonine-protein-kinase
MSELKKGDVVALAGGDTCQVVRELGRGGQGIVYAVNYNGSEYALKWYTQKVSERFRENLKRNANRQTPNEHFIWPMAVAEDPNGGFGYLMKIRPAGYVDMSKFILVTARFADVNAQLNACMQLVKSFLDLHRDGYSYQDMNDGNFFINPKTGDVLICDNDNVAPDGTDDLGILGKAGYMAPEIVEGKSRPRKVTDYHSLAVCLFILIYMNRPFEGRRYLSCPCDNDPEMARQLLGYNAVFIMDPNDKSNAPDPSLHKNVMRRWDIYPKVLRDAFCKTFSKEALQNGDLRVKDKEWRDILLQVRADFVKCPKCGKFSFADPDSVDKKCAYCDKSFGDYRMLRVGKFKIPLMMEQKLHECLVHCSTDYDKVVGRTVVKNNEVGLCNNSGESWTVTCLDGTQRVVADGQGMPARKGYKIKFGNQGETAVIE
>NC_017448.1|WP_012819978.1|598383_599154_-|VWA-domain-containing-protein
MATKDPFALEPIPRRVTHLIFMVDTSGSMSGSKIASLNTAVRDALDDVGDISKNCGDSQIKIAVLEFSSAVNWMYEQPLEAEKFQWQDLSASGTTSFGSACAELDAKLSRSNGFMGEKTGCRAPAIVLLSDGAPTDGYVRKLEKLKGNRWFKAGVKVAIAIGDDANNDVLREFTGSSESVITVHNVDQLKKMIHTVSVSATTVASQSASVGAAMVTQNQLVAQSISNTVANDASLSGVDVGSSTANSGSNDWSGWN
>NC_017448.1|WP_012819977.1|597389_598367_-|protein-phosphatase-2C-domain-containing-protein
MQNAETFAVSKVGAKHLPANIPCQDFSLEYNDGEIQLIVVCDGHGSPSYVRSDVGARLAAGIAKDELMQFMQSEDARKFLGNRTGAVTARTDVGDSCWTEKSEEKSETAKLREEQAMLYQQQIGNIQPQEKLIRDVCRRICEKWVAAIQQDAQENPLTDAEKELLGKNDLVKAYGSTLMAYVQTRWGWLAIHVGDGRLLCLNDSAEPYENWTPPVPWDSTCFLNYTTSLCDKNPADSFRYAFDGTGHFPFAVFACSDGIEDSVGDYDVAPECLNRFYMRLLQMYLDIGKEQAVARMDEGFSDMSLHGSKDDMSLAGIINKKGNEQ
>NC_017448.1|WP_012819987.1|615188_616049_+|4Fe-4S-binding-protein
MAVDYSTLKKGGWMRQKQKNNFSLRVRVVGGNLTATQLAKIAEVAEKYGEGYAHLTSRQSVEIPFIKLENIDDVKNALAEGGVEPGVCGARVRTITACQGEAVCPSGCIDTYAIAKELDDRYFARELPHKFKFGVTGCQNNCLKAEENDVGIKGAIKVDWLEDKCIGCGLCAKVCRKEAIKIENKKVIFDKEKCNYCGRCYKSCPTDAWSHIHGYIVSFGGLFGNNINKGETIIPFVEDKQKLLDICDAAIQFFADNGKSGERFKYTIDRVGRDVFAKKIQDVYNG
>NC_017448.1|WP_012819988.1|616092_617856_+|adenylyl-sulfate-reductase-subunit-alpha
MNIEKIKTDLLIIGGGTAGCYAAITASTLGAAKDVADIKILVVEKANIKRSGCLAAGVNALNAYITEGRTPKDYVEYAKKDADGIVREDLLYSISEKFNEVTAHLEKLGLVILKDKDGKYVTRGNRNIKINGENIKPILAAAVAKAPNVQVLNHVNIFDFSVHDNRIDGAFGFGIENDTFYAIEARAVIIATGGAAGLYRPNNPGFSRHKMWYPPFNTGAGYAMGIRHGAEMTTFEMRFIALRCKDTIAPTGTLAQGVGAKQINSLGEVYETKYGISTSERVYGTVAENLEGRGPCYLRTVGITPAQEDSLLKAYLNMAPSQTIRWLENETPSKANVEIEGTEPYIVGGHTASGYWVDTKRATTIDGLYAAGDVAGGAPQKYVTGALAEGEIAAKSAVEYINAVDCRTPLQGVRNDVDADPREDVDAKATIKEAEIARHVAEIETYLSQKNSLYTTEQLEEAMQIAMDEYAGGIKTGYGYSEKHLNIAKEKIDEIESLTDKLSAADLQEVMYIYELKERLTVCKSVIAHLKARHETRWHSFAENLDYPEKDNANFRKYVNSRLENGEIKIILRDLTAEGQKNYEHQH
>NC_017448.1|WP_012819989.1|617839_618154_+|ferredoxin-family-protein
MSISIDQSKCIGCRRCHDVCPGTLIKINEDKKAFIKYPKDCWGCTSCIKECPVHAIQFFLGEDIGGKGSKVHTEKVNGLIRWIVEFPDGNVKSIDIDPKESNKY
>NC_017448.1|WP_012819990.1|618164_619064_+|sulfate-adenylyltransferase-subunit-CysD
MSEFSHLDELEAEAIYIIREVAAECEKPVMLYSIGKDSSVMLHLAIKAFYPEKPPFPFLHVNTTWKFREMIEFRDRTAQKLGIEMLEYINQDGVKQGINPFDHGAAYTDIMKTQALKQALNKYGFTAAFGGGRRDEEKSRAKERIFSFRNSAHAWDPKNQRPEMWKLYNTKINKGESIRVFPISNWTEKDIWQYIKRENIDIVPLYFAAPRPVVVRDGNIIMVDDERFPLREGEKPEIKSVRFRTLGCYPLTGGIESTATTLDEIIDETLSAVSSERTSRVIDNEAAGSMERRKREGYF
>NC_017448.1|WP_012819991.1|619063_620749_+|sulfate-adenylyltransferase
MKGLLKFITCGSVDDGKSTLIGHILYDSKLLYTDQEKALELDSKVGSRSGKIDYSLLLDGLMAEREQGITIDVAYRYFTTDHRSFIVADTPGHEEYTRNMAVGASFADLAVILVDASQGVLVQTRRHARICRLMGIRHFVFAVNKMDLVGYSEDVFNKIKVQIAELAQTHSLSNIQVIPLSATEGDNVTIKSKNIAWYQGPALLEYLENVDTSSSALEKGFYMPVQRVSRPDRTFRGFQGQIESGTIRVGDVIKSLPSYEKASVKSILYTNRNVEEAHAGEPVTITLDREVDVSRGCVLARDASIGSYKKIKASLLWMDDEPLSLGKDYLVKIGTKIIPGTLTKIDYAIDVNTGAHLETESISKNGIAVCEIVFAEAIVVDLFEKHKTLGELILIDIVTHATAACGVVEGLYEKQLQSNEKAAFVQGERHGRGEIFEEFFYDTATLSVVKQQPVKQHYTVGDEIPTAGESYHYPDDFDIIILRDSIAVKVRGKRIAEITTAEEYHYGNVPVINGRGFEIKVHSDEDVKQLLNEYEKAGIAGREEFFRKWASFNTYRKVVLH
>NC_017448.1|WP_012819992.1|620970_621990_+|hypothetical-protein
MNQTISKILITTALVSSICSAAESANESTFKLTGNVQAQAIKSLYDNDADNTLDNSFLRANIGAKYNSENLSAVINLRIFSPAFGNTIEGKNYDKISADTYYANYKWDTEYGKFNVQFGRFRTDWSVGGNFGTYVDVALNKRGFLARDYQHDAFAFGFEKGISTFNALLGTYDAKFNTGYIRFEETLKFGDAKVSAAYRVNALDVIQHTAQLTHRAAARASYYFQKNFGLYGEVALIATGDGENLKAANAIKPEYAQDTQYIPFFVGVEIPTAGIFNNVYAELEYVSHRDELQAGADGIAWTVSFIKKINDYSKIQVNVYSEKKASDVALAARFTASLK
>NC_017448.1|WP_012819993.1|622101_623121_+|sulfate-ABC-transporter-substrate-binding-protein
MNFKKITIASIALLSIAFTACSSSDSKTESTKQTLTNVSYDPTRELYANYNQVFAKHWKEKTGKDVEITQSHGGSGKQALEVANGLEADVVTLALEYDVNAVRDAGLIEDGWVKEFPLNSAPYTSTIVFLVRKGNPKNLKDWGDLVKDGIGVITPNPKTSGGARWNYLAAWAWAEKQYNGDEAKVKEFVKKLYKNVLVLASGARGSTTTFIENGQGDVLLAWENEAFLSLKDYPNDYEIVIPSVSILAEPSVAIVDKVVDKRGTRELATEYLNFLYSDEGQHIAAKNHYRPSNKAILDQYKEFDQNVNLIDISYFGGWDKAQKTHFSNGGIFDQIYEKK
>NC_017448.1|WP_012819994.1|623276_624110_+|sulfate-ABC-transporter-permease-subunit-CysT
MKRTNRSVIPGFGLTTGITLAILGVVVLIPLASLVVFTAQMSFDEIIETITRDRVLSSFRVSFTTAFIASFINAVMGIILAWVLVKYTFPLKRLIDGMIELPFALPTAVAGIALTALTADTGLVGGFFAKFGIKIAFTQIGITVALVFIGIPFVVRAVQPVLEKLDPAYEEAAGVLGASRGRIFWKVIFPEIVPAALTGFGLAFGRCLGEYGSVVFIAGNKPFETEIAPLIIMSELQEYDYASATTIALVMLVASFVTLFLVNLIQTRNTKILKGGA
>NC_017448.1|WP_012819995.1|624109_624931_+|sulfate-ABC-transporter-permease-subunit-CysW
MYKETTSSKIVKWSLIGISIAFVVLMLLLPLITVIAEAFKQGFDIYAKAVSDNYTIKAIWLTLEATLLAVIINTVFGLSAAWSLTKFHFKGKKILTTLIDLPVTVSPIIAGLIFLLTFGRQSPIYPLLQSWDIKIVFAVPGIVLATIFVTFPFISRELIPVLEARGNDEEEAAALMGAKGWTIFRKITFPHIKWAFLYGVVLCAARAMGEFGAVSVISGHLRGKTNTLPLHVEILFNEFQYVPAFAVSSILVMLAIAILIARSAIEYRGRKKI
>NC_017448.1|WP_012819996.1|624942_626001_+|ABC-transporter-ATP-binding-protein
MYVELKNINKHFGNFKASDNVSFGIEKGKLIGLLGPSGSGKTTILRMIAGLENPDSGEIIIDGKVINNVPASKRGIGFVFQSYALFRYMTVFENIAFGLRVLKKSENEIKERVAELVKLIGLEGLENRYPSQLSGGQRQRVAFARALAPNPQLLLLDEPFAAIDAKVRQELRHWLKEMIAKLGVTSIFVTHDQDEAIEVADEIIITNKGRIDQIGKPLEVYSKPKTAFVASFFGQPSIFKDYNKFHSFDTIPNVDQAIVRPEFVKVTKKNEVQKFKNSAEEGVVTDVAFRGSGIEITVLVNGETLTARRSFDEPSISVGEKVDVFIYRLFVTVGNYAFLLENKSIREPIVVI

Crispr_ID: NC_017448_2

• CRISPR_ID: NC_017448_2
• CRISPR_location: 819353-819507
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_017448_2

Consensus_repeat	Method
CTTCGAAGGCGCAAACCTCGAAGGCGCAAACCTC	PILER-CR

spacers of NC_017448_2

>2.1|819388|34|NC_017448|PILER-CR
TCCCGAAGTCTCTTTCCGCAATGCCGTGATTAGC
>2.2|819457|41|NC_017448|PILER-CR
AAGGGTGCAACGATTAGCGGCGCAGACATTCGTTCTGCAAG

CRISPR arrays and Neighbor proteins around NC_017448_2

CRISPR arrays

The CRISPR arrays of NC_017448_2

>merge|NC_017448|2|819353-819507|PILER-CR
CTTCGAAGGCGCAAACCTTCCCGAAGTCTCTTTCCGCAATGCCGTGATTAGCGGCGCCAACTTCGAAGGTGCAAACCTCAAGGGTGCAACGATTAGCGGCGCAGACATTCGTTCTGCAAGCTTCGAAGGCGCAAACCTCGAAGGCGCAAACCTCT

>NC_017448|2|3|819353-819507|PILER-CR
CTTCGAAGGCGCAAACCTTCCCGAAGTCTCTTTCC	GCAATGCCGTGATTAGCGGCGCCAACTTCGAAGG
TGCAAACCTCAAGGGTGCAACGATTAGCGGCGCAG	ACATTCGTTCTGCAAGCTTCGAAGGCGCAAACCTCGAAGGC
GCAAACCTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_012820163.1|810336_810783_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|366181
NC_017448.1|WP_012820181.1|830170_831136_+|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl|CDD|237004
NC_017448.1|WP_012820178.1|827708_828782_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl|CDD|223890
NC_017448.1|WP_012820165.1|811569_813504_+|T9SS-type-A-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|378986
NC_017448.1|WP_012820169.1|816255_816669_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	unknown	unknown	gnl|CDD|376771
NC_017448.1|WP_012820177.1|827302_827668_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NC_017448.1|WP_012820175.1|822027_825993_-|EAL-domain-containing-protein	unknown	unknown	gnl|CDD|238923
NC_017448.1|WP_012820167.1|814749_814995_+|DUF1653-domain-containing-protein	unknown	unknown	gnl|CDD|377930
NC_017448.1|WP_012820166.1|813550_814537_-|RelA/SpoT-domain-containing-protein	unknown	unknown	gnl|CDD|223394
NC_017448.1|WP_012820174.1|820536_821928_-|DNA-repair-protein-RadA	unknown	unknown	gnl|CDD|236994
NC_017448.1|WP_012820171.1|817380_817827_-|SufE-family-protein	unknown	unknown	gnl|CDD|376883
NC_017448.1|WP_012820180.1|829559_830057_+|YchJ-family-protein	unknown	unknown	gnl|CDD|225557
NC_017448.1|WP_012820183.1|831397_832600_-|fibrobacter-succinogenes-major-paralogous-domain-containing-protein	unknown	unknown	gnl|CDD|273995
NC_017448.1|WP_012820172.1|817834_819031_-|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223717
NC_017448.1|WP_012820164.1|810858_811302_+|membrane-protein	unknown	unknown	gnl|CDD|226720
NC_017448.1|WP_012820170.1|816678_817371_-|hypothetical-protein	unknown	unknown	gnl|CDD|235334
NC_017448.1|WP_012820179.1|828775_829396_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|368581
NC_017448.1|WP_012820176.1|826261_826999_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|212491
NC_017448.1|WP_012820168.1|815047_816175_+|carboxynorspermidine-decarboxylase	unknown	unknown	gnl|CDD|143502
NC_017448.1|WP_041259984.1|832654_832873_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_012820163.1|810336_810783_+|GNAT-family-N-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.71275e-10
NC_017448.1|WP_012820181.1|830170_831136_+|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl|CDD|237004	PRK11863, PRK11863, N-acetyl-gamma-glutamyl-phosphate reductase; Provisional.	0
NC_017448.1|WP_012820178.1|827708_828782_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl|CDD|223890	COG0820, COG0820, Predicted Fe-S-cluster redox enzyme [General function prediction only].	1.5676e-116
NC_017448.1|WP_012820165.1|811569_813504_+|T9SS-type-A-sorting-domain-containing-protein	gnl|CDD|378986	pfam12891, Glyco_hydro_44, Glycoside hydrolase family 44. This is a family of bacterial glycoside hydrolases formerly known as cellulase family J, and now known as Cel44A. It is one of the major enzymatic components of the cellulosome of Clostridium thermocellum strain F1 and of many other Firmicutes.	6.29393e-61
NC_017448.1|WP_012820169.1|816255_816669_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE	gnl|CDD|376771	pfam02367, TsaE, Threonylcarbamoyl adenosine biosynthesis protein TsaE. This family of proteins is involved in the synthesis of threonylcarbamoyl adenosine (t(6)A).	3.33546e-46
NC_017448.1|WP_012820177.1|827302_827668_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.51229e-11
NC_017448.1|WP_012820175.1|822027_825993_-|EAL-domain-containing-protein	gnl|CDD|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	4.97978e-79
NC_017448.1|WP_012820167.1|814749_814995_+|DUF1653-domain-containing-protein	gnl|CDD|377930	pfam07866, DUF1653, Protein of unknown function (DUF1653). This is a family of hypothetical bacterial proteins of unknown function.	8.00035e-27
NC_017448.1|WP_012820166.1|813550_814537_-|RelA/SpoT-domain-containing-protein	gnl|CDD|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	7.11852e-09
NC_017448.1|WP_012820174.1|820536_821928_-|DNA-repair-protein-RadA	gnl|CDD|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NC_017448.1|WP_012820171.1|817380_817827_-|SufE-family-protein	gnl|CDD|376883	pfam02657, SufE, Fe-S metabolism associated domain. This family consists of the SufE-related proteins. These have been implicated in Fe-S metabolism and export).	3.43303e-41
NC_017448.1|WP_012820180.1|829559_830057_+|YchJ-family-protein	gnl|CDD|225557	COG3012, COG3012, Uncharacterized protein conserved in bacteria [Function unknown].	2.76031e-52
NC_017448.1|WP_012820183.1|831397_832600_-|fibrobacter-succinogenes-major-paralogous-domain-containing-protein	gnl|CDD|273995	TIGR02145, Fib_succ_major, Fibrobacter succinogenes major paralogous domain. This domain of about 175 to 200 amino acids is found, in from one to five copies, in over 50 proteins in Fibrobacter succinogenes S85, an obligate anaerobe of the rumen. Many members of this family have an apparent lipoprotein signal sequence. Conserved cysteine residues, suggestive of disulfide bond formation, are also consistent with an extracytoplasmic location for this domain. This domain can also be found in small numbers of proteins in Chlorobium tepidum and Bacteroides thetaiotaomicron. [Cell envelope, Other].	7.61597e-64
NC_017448.1|WP_012820172.1|817834_819031_-|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	8.04994e-46
NC_017448.1|WP_012820164.1|810858_811302_+|membrane-protein	gnl|CDD|226720	COG4270, COG4270, Predicted membrane protein [Function unknown].	8.33109e-06
NC_017448.1|WP_012820170.1|816678_817371_-|hypothetical-protein	gnl|CDD|235334	PRK05035, PRK05035, electron transport complex protein RnfC; Provisional.	0.000334516
NC_017448.1|WP_012820179.1|828775_829396_+|methyltransferase-domain-containing-protein	gnl|CDD|368581	pfam05724, TPMT, Thiopurine S-methyltransferase (TPMT). This family consists of thiopurine S-methyltransferase proteins from both eukaryotes and prokaryotes. Thiopurine S-methyltransferase (TPMT) is a cytosolic enzyme that catalyzes S-methylation of aromatic and heterocyclic sulfhydryl compounds, including anticancer and immunosuppressive thiopurines.	1.82335e-27
NC_017448.1|WP_012820176.1|826261_826999_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	1.00578e-37
NC_017448.1|WP_012820168.1|815047_816175_+|carboxynorspermidine-decarboxylase	gnl|CDD|143502	cd06829, PLPDE_III_CANSDC, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase. Carboxynorspermidine decarboxylase (CANSDC) catalyzes the decarboxylation of carboxynorspermidine, the last step in the biosynthesis of norspermidine. It is homologous to eukaryotic ornithine decarboxylase (ODC) and diaminopimelate decarboxylase (DapDC), which are fold type III PLP-dependent enzymes that contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain, similar to bacterial alanine racemases. Based on this similarity, CANSDC may require homodimer formation and the presence of the PLP cofactor for its catalytic activity.	0

Protein sequences

>NC_017448.1|WP_012820172.1|817834_819031_-|NAD(P)/FAD-dependent-oxidoreductase
MTCFRSNSYKVVICGAGPAGLMAAYQLGKLTGGDGQILLLDKKEPWKEPIFCAEAVSTHRLNELWPIDESWVRGSLSGIYFTSPKGYKAEFYSKDCGRLLDRSKFHHAIADACVESGVECRFDALVKSIEKTENGWNLNVQVGKEFFSLSADAFIDASGPGCRLTRGIPCLEGIESGDTDLEPGIFAVAEGIEHDRDHIDLLYGSEFPGGYGWIFPRDGKEVNVGFVLSKDAKPDMPLREKLKHFIATHYPNAKVKAIYGGMIACGQSDKPLAKCGLFKAGDAASCVNPLSRSGIVEALLSGKIVAEAVHEWLNASDDAARSRIEASVLDRWMAKLGKSHLQIARAKPGLAKIKDEQFDKAAKRLSKLPREKQTLLRIFWAVLWSCPSVIWKMRSFLH
>NC_017448.1|WP_012820171.1|817380_817827_-|SufE-family-protein
MSESIVDRQEKIRAKFASFTDPDDKWKFLLDLAREHKGMDASLKAEKFIIQGCASTMYLVPKFDGAKIHFEMDVEGGTTNPLISRGLGALALQIFNDMAPADILSVDPTFFQQIGLNVGLSPTRSNGFASLLKQIYLYARVFDAISKK
>NC_017448.1|WP_012820170.1|816678_817371_-|hypothetical-protein
MFSFLNGKSPFDEAEEKLEAGETINGRPKLPQAPIMGWQDGVFLLVLIGLIAGGYYYYQYAKQKSATMFANCDALYVAAETNAAKYVDAEACYNETWDLGFVSDSMEILRQNRLGAIEDLRNHQKDLYADAMGAMAARDTVAAYKVVTEYNGPMLLSQGDRKDWNNIANNDAVKASVAAAVARADSIAKEKAIADSLAQVAAELRAKAVADSIEKANKKLARKGKRKKAQ
>NC_017448.1|WP_012820169.1|816255_816669_+|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE
MKFKSEDETYNWALEFAKELKVGDKVALYGNLGAGKTVISRGICKGLGFEGTVCSPTYTILHEYPNNPPIFHFDLYRLEGGADLYEVGMDPDYLERGISLIEWPERLEENDAGITHVVKIQIVSETEREITVEKIAK
>NC_017448.1|WP_012820168.1|815047_816175_+|carboxynorspermidine-decarboxylase
MLDYSQVPSPCFVLDETRLRRNMEILDDIQKKTGVKIICALKGYSFWRSFPLIGEYLAGATASSLNEARLAREEMNKEVHVFAPVYEDDEIDAILDAADHITFNSFSQWQRYKDKTLAHGVSAGIRVNPEFSTVETDLYNPCGKFSRLGVTEKEFKPELLDGIDGLHFHALCEQDADALEGVLAAFEKHFGKYLPQMKWVNFGGGHHITRKDYHRDELVRILKDFSARYPHLQVIMEPGEAIGWQTGELVTSVGDIVHNEMDIAILNVSISAHMPDCLEMPYRPSVIGAAFPGEKAHTYKLTGNSCLAGDQLGDFSFDEPLKVGDRIIFEDMIHYTMVKTTFFNGVRHPSIGKFDENGKFHLLHKFTYEQFKEKL
>NC_017448.1|WP_012820167.1|814749_814995_+|DUF1653-domain-containing-protein
MENRELKIHGIYKHFKNRYYIVEGVAKHSETDEEYVIYRKLYGDNAMWIREKSMFLSEVDHEKYPEVKQKWRFEEVELGQQ
>NC_017448.1|WP_012820166.1|813550_814537_-|RelA/SpoT-domain-containing-protein
MISLNDYLFSGNTVLKILHQYSNDLRNSAKETHNSIDLAHSNFLIQIIELLEHNDFLTSQSQRIKEFYKYMTREYPFLAFTFKGRIKSLIRAEEKFNGYILEFVYNYYKKNGVFPSEAEIKSTLNFRDLIAYRIVISMPACHIKKGEERSEVERKYLYEIANVMPEFLEERGFTPEISRHKDGGHCDLLKDAVQPYYHDSVATPRSSGYQSLHITMYDNLARCYTEVQLRTKDMDDFAEIGDANHFGYEKTQETRRSKHDQIPSGECVYFDDAYERLTKLQELELSKLDVNMFKAINNQLINDGCGLFRGRQILPFEHLSRFQNDLID
>NC_017448.1|WP_012820165.1|811569_813504_+|T9SS-type-A-sorting-domain-containing-protein
MGYSNFFTVAAFGTLFAISPTLAIDITVDANAGIKKISPYLYGRNIDKISDGDAEVTEEESAFINQMLEAGIHMLRANNGNNATRYNWRHKMTVHPDWYNNVYSHDWAITAQKVLDKMPGVDAMYAFQLTGYAASSTDYNFPDWNWKQEHGTYATQTFDLAGGGEVSEDGKTLIKAGDPSLYNMEWPADSTVAIIPHWKDELKFDMSRFKYWSMDNEMEIWRGTHNDLDLPVTGDFLVERYIDVAKKARAAWGDIKLTGPVAANEWQWCSVSSYNKEDRPKGEDRNYCWLEYFIMKVAEEQKKSGVRLLDVFDIHWYPTEKDYESRVNWHRVLFDTTYNYPGANGIKMVGGNWDNKVTKEYIFVRINQWLEKYFGKDHGITLGITETSIIDNDPMVTALTYASFLGTMQDNGVEIFTPWTWGDGMYETVHLFSRYGHPNRVQSTSSNDSLVSAYSSISNKGDSLTVIFVNRAEKDAQEINLDLANFASDGTVKTLTLQNLQGETFVSHTSNALKENAVEANAQGGTTTATGYSINRFKMTLPAKSITAVLLTTTTPKQIDAIAPTRSTLSGNLLHQENGNWFIDNGSGKVRRINVFNSLGQSVLRIQQPARGNFRIASEVLSKGNFIVRIETASGTQMQKITVK
>NC_017448.1|WP_012820164.1|810858_811302_+|membrane-protein
MKYLKMFCRGLLGLFMTYAGFSHLTIARQEFLAQVPSWFPQNPGFLDFVVLASGVVEILLGLSMIFLYKHKGTVGVLLALFYVAIFPGNISQYVNGISAFGLDTDQARFIRLFFQPVLIAWALWSTDGVQKLKEWRNRYCNKRKESK
>NC_017448.1|WP_012820163.1|810336_810783_+|GNAT-family-N-acetyltransferase
MIIAINKDDPWWEKTRAFAKDCPWLPGRRLAERMSKNDFLDWEKVFVAVHGEDVVGFCVLEENGNTPAQFNCSPFINLVYVGEEFRGERLSKSLIDAALDYAQRLGYKKVYLKSEHHGLYEKYGFKKIADFKPTVGLANQLFEIEISV
>NC_017448.1|WP_012820174.1|820536_821928_-|DNA-repair-protein-RadA
MVAVNKSKKEIEYLCTECGNTTPKWAGKCPFCGAWSSLKEHVIERITDGAGRTGRGLGGPVHKVVLLKDVAAEDTRRLSTANSEFDRVLGGGFAPGSLVLIGGDPGIGKSTLVLTTLATMNAAGVKALYVSGEESACQVKLRSERLNVSGSDMMLLCETNLEKILEQAKEVKPQVLVIDSIQTVYKSDLSGTPGCATQLRECTLDLMVFAKNSGCITILIGHVTKDGQIAGPRILEHMVDTVVYFEGDRNHQYRLLRTIKNRFGATDEIGVFEMTSHGLNPVLNPSKVFLQEGVPPTPGSAVCCTMEGSRALLFETQALVNQTNFAVPQRVAAGIDPKRLTIILALLEKFGGVTIGASDVFASIAGGMKVNDASSDLALALAVASNHLGIPLSRQTIAIGELGLSGEVRGVSLLDQRLKEASRLGMTEAVVPASCKLSENMGSMKVVRVHSLSEAISWLMDKK
>NC_017448.1|WP_012820175.1|822027_825993_-|EAL-domain-containing-protein
MSDAGEKKIPEGIRNELEHSEVPLAVYRFVDGHIQTILVSDGLVRWQAPGSTREDLLKFLDTDMYRDVHREDIVFVATKAKEFAKSKDGRYEVVYRQKLYGKDEYRTLHAQGYHRVLDDGSECAIVVYDDVTSAFDTCKNFRNEFDNSLIEFLNNDSVEPFVIVDAKTHEIYMLSASVDKVWTPVKAFDSGITFEEYFFDPNEVQLITLEEVLEKGEVLVPNSRTGGDLILKASLIKWHGKDAIFHRISERTDRYFDTLTGLPNMEYCRMRGESYVTDIRIAGGTPSVAFFDIVGMKLYNNANGYDKGNEFLLNFAAALKKVFPNNLICRLANDHFTVVADMKNIEDKLCEVRKYVKSVVSKISMDVNIGISKIDEFETMVDANEKAKIACKVQKSSSDSFVRYYDEDLRKALVLQNYVVNHIDEAIKNGYIKVYYQPVVRTITETFCGMEALARWVDPQYGFLNPAVFIGALEESRQIHKLDSHVINIVCKEMRAELDAGKPIVPVSFNLSRLDFIGCDIFDVVERALEKYSIDREYIRVEITESIMASDSYVRSEIQRFRLVGYEVWMDDFGSGYSSLNTLKDYKFDELKIDMAFLSNFNDASRTIISSTVRMAKNLGLKTLAEGVETKEQMDFLKGIGCEKVQGYYYGKPQPLKDTMKHMESIGMAVEDHNARVVYSKLGSLDYLVDSPKGILSYKDGLFKFLFVNKQFEEQISSLGFAHIEDVEKAINDPKDPAYYTLHEAEKAAYTGPREITYAARGSYVFLSGCLIADIEGNHIYDMSLRNTHVSAFDISSSSSKITSLPTDAKTILLADMNPQNRAFLESVLRSNYNLLLAEDGEQVLNFLLEYGNHISLALIAADLPKIDGFKIIQKFRGEKRECQIPFIVMTDNMELAKEGMRLGAYQFIHTPITSRDQVKSKIDGAIKNTEVLHQLALNYMEYVPGGVILLEAVSGDILYVNGRALEIFDCDNVDDFRSLAGNKFEGAVLPEDYAAVDETLETLFRSRSALPSQTTYRVRTKKGFVKRIYHVGRYFRDTPYGRILSVFVSEDDMALKNYFGRKNAFKLFMASGEATHTKSYEPGYKGYLFWNLTRNSPVIRMDGISYIPKELTGKYTYDAHFDYLVELMSKDSVNIQKTSSYTREKLILAYANKRAVPSLNLNYNLKNGWFSIKSTFDMMADPDTGDVILKLQNENDTDVEAYKELTDAVVMNLYDQIIYLDGNTDRLLSLSCLEGKPMYVQRTISDSMDNLCKLFQMPVCTAEKFMEIAKMRSASGETYGRTLTLDDGHVKFVRAKPLYNGSDKYIITVSDITHAKKEFQ
>NC_017448.1|WP_012820176.1|826261_826999_-|SDR-family-NAD(P)-dependent-oxidoreductase
MIDVKGKWCLVTGGCRGVGRLIAIEMAKLGANLILQGRDKSHAEKVIAELAPYGVQVKAVGCNLENEAEIEAALAEIDSFGVQVDLVFNNAGLMSHYFSDYTTNTMDDFRQAMAVNFFAPIKIAYHFLPGMIKRGFGRMQLTTSGIANEPELAAYACAKAALTKFVKDFACKLNGTDVMMNVMDPGWLRTDLGGPNAPNAPETVVPGALVSVLLDDKKSGRWFSAQDYVGKSVADAVEAGRNVFA
>NC_017448.1|WP_012820177.1|827302_827668_+|helix-turn-helix-transcriptional-regulator
MNYETLLLHEAIRLLIISIRQQRRHTQQSLSLESGISRQYISQMECGKRIPSLDTLSQLAIALKTSMGSLMSEMDRIYQHLFWQSKTDQVDKNDDFSARNAAETHNPSLEYIHRAGGLDKP
>NC_017448.1|WP_012820178.1|827708_828782_+|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MEWQRNIKTLTTDELKAWLRDVDEKPYRADQIQKWLFCQQVRSYDEMVNISPALREKMAKQFTLCGLKEDQRSVSVDGTVKWLFETEDGHHIETVMIPANGRYSVCVSTQVGCAMNCAFCRTAKMGFTRNLEAGEILEEIINVNWYLKDNGFMNEEGGVAQVTNIIFMGMGEPLNNLENVHRVCCTLHNQKLFNMGAKRMTVSTSGVVPKIKELVDRNTPCCLAVSLNSTNNEYRSSVMPVNKTWPIEKLLEAVDEYIRRTDNYVTFEFVLIQNITCTPKAAKELIRICAPRRVKVNAIVLNDGDDPTLHAPTPEEVEDFLAAVRAAEIQITIRNPRGRDILAACGQLAYKKEGKEC
>NC_017448.1|WP_012820179.1|828775_829396_+|methyltransferase-domain-containing-protein
MLTQNLPEFWDNLYAEGKDYWNFKKATPALLEFFKHPSCPAEGSVLIPGAGFGYDAEAWALRGHDVLAVDFAPTAVDELDHLSRKHKNLRSLDLDLFTLSPKDAKRGGQQFDIIYDYGAFSAIHPGRRDEFFEVCYRMMKDDGVFICLMYPLMNGKTMQGPPHCMSEGELMARLDGVFDIVERIKPTNSIPGREGKEEFWLLKKCL
>NC_017448.1|WP_012820180.1|829559_830057_+|YchJ-family-protein
MANDLCPCGSGKAYCDCCEPIIKKTTLAPSPEALMRSRYTAYAKHEIAWLKDSLEATQRDDFDEPSVEAWSRQSEWLGIEIKQTKTEEDKNIGWVEFVARFKQGNITRNHHELGEFHKVGGAWYFYDGRAVKQETVRHEGPVVGRNDPCPCGSGKKYKKCCGANK
>NC_017448.1|WP_012820181.1|830170_831136_+|N-acetyl-gamma-glutamyl-phosphate-reductase
MFKVFVDGEAGTTGLQIFERLAKRNDLEILKINPELRKDVNERQKMINESDVTFLCLPDAASMESAALCTNPNTRIIDASTAHRVNPAWTYGMPELSAEQREAISKSKRIANPGCHASGFILGVHPLVASGILPKSANLAAYSITGYSGGGKKLIAEYEAEDALSHKAGESKAIMAPAPYALALAHKHLPEMKKYCGLENVPFFNPVLGPYYKGMAVTVAIFPNMLSKKVGPQDLTEILAKHYEGSKFVKVLPYEAAPVLFNGRLDPTVCNDTNNARIQVFGNENIMQVTTIIDNLGKGASGAAIQNMNIALGLDETIGLV
>NC_017448.1|WP_012820183.1|831397_832600_-|fibrobacter-succinogenes-major-paralogous-domain-containing-protein
MLKVKKGILFCLSIVTVGFFAACGDDPSSSNSATPAQENILPEEPEKVEVSSSSVNVVPASSAEISASKPTIPSYTVEKGTMVDERDCRTYKTITIGTQTWMAENLKFEYKVDGKTYGNSCNPDSCETFGRHYTWAAAMDSAVVFTNDSENCGYGVTCSPTYPVPGICPEGWHIPDSTEWVEFYKILNEDPHAMQAEDFIRSKSAIRKGLVATNASGFSALYETLSLVAGHTASGAFFWSSTDYITSRAYYWHVSESEARLDNNKICDKGTGMAVRCIKDFGTVVTPSSSCVEEPPVSNVENPVDTVSSTIIKLSSSSQAVKSSSSKDKGDRMFYLPTLIQACAYANLGNARFIECKSPNAIDCLQKINGCNFDAVEYCGCWESEDAYIYYRNKDKGQIR
>NC_017448.1|WP_041259984.1|832654_832873_-|hypothetical-protein
MARPIRETPILYGEDARRFLENMKIRRPETPEARAQRLRDYEFMKKAYERGMAEQRAREEANGGFDPWFKKV

Crispr_ID: NC_017448_3

• CRISPR_ID: NC_017448_3
• CRISPR_location: 2341980-2342559
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: cas1,cas2,csx1,cas10,csm3gr7,csx10gr5,csx19

Consensus repeat of NC_017448_3

Consensus_repeat	Method
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	CRISPRCasFinder
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	CRT
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	PILER-CR

spacers of NC_017448_3

>3.1|2342011|42|NC_017448|CRISPRCasFinder
TAAGACTTAAACTCTTTTGTTGCTTTGAAGGGATTAAAATAG
>3.2|2342084|43|NC_017448|CRISPRCasFinder
TAAGACTTTCATATTGTTACCTCCTAGAATTTTTCTATTCCCT
>3.3|2342158|43|NC_017448|CRISPRCasFinder
TAAGACTTTGCAATCTTTGCCATGATCTTGGTCTTAGTGTTTT
>3.4|2342232|42|NC_017448|CRISPRCasFinder
TAAGACAGAACACGCATTTCAGTATCGAGCCTTTCCTTGTCA
>3.5|2342305|44|NC_017448|CRISPRCasFinder
TAAGACCATCACTCATCTTTTTGAGTACCTCTGCAGGTACATCA
>3.6|2342380|74|NC_017448|CRISPRCasFinder
GGCAACCTGGCGGTTGCCTGCTTGTCGGCTCGGTCATGCCCACGCAAGCGTGTTCGCGACGCTCGCCTCTGTCG
>3.7|2342485|43|NC_017448|CRISPRCasFinder
TAAGACGGAGCTGGTTCCCATTCAGCAGATTCAATTGCTGATC
>3.8|2342017|36|NC_017448|CRT
TTAAACTCTTTTGTTGCTTTGAAGGGATTAAAATAG
>3.9|2342090|37|NC_017448|CRT,PILER-CR
TTTCATATTGTTACCTCCTAGAATTTTTCTATTCCCT
>3.10|2342164|37|NC_017448|CRT,PILER-CR
TTTGCAATCTTTGCCATGATCTTGGTCTTAGTGTTTT
>3.11|2342238|36|NC_017448|CRT,PILER-CR
AGAACACGCATTTCAGTATCGAGCCTTTCCTTGTCA
>3.12|2342311|38|NC_017448|CRT
CATCACTCATCTTTTTGAGTACCTCTGCAGGTACATCA

CRISPR arrays and Neighbor proteins around NC_017448_3

CRISPR arrays

The CRISPR arrays of NC_017448_3

>merge|NC_017448|3|2341980-2342559|CRISPRCasFinder,CRT,PILER-CR
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGACTTAAACTCTTTTGTTGCTTTGAAGGGATTAAAATAGCCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGACTTTCATATTGTTACCTCCTAGAATTTTTCTATTCCCTCCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGACTTTGCAATCTTTGCCATGATCTTGGTCTTAGTGTTTTCCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGACAGAACACGCATTTCAGTATCGAGCCTTTCCTTGTCACCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGACCATCACTCATCTTTTTGAGTACCTCTGCAGGTACATCACCCTGAAAAGCATTACTCTCGCAAGAGAGATGGCAACCTGGCGGTTGCCTGCTTGTCGGCTCGGTCATGCCCACGCAAGCGTGTTCGCGACGCTCGCCTCTGTCGCAGTAAGACTTGGAACTCTCGCAAGAGAGATTAAGACGGAGCTGGTTCCCATTCAGCAGATTCAATTGCTGATCCCCTGAAAAGCATTCCTCTCGCAAGAGAGATG

>NC_017448|3|2|2341980-2342559|CRISPRCasFinder
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	TAAGACTTAAACTCTTTTGTTGCTTTGAAGGGATTAAAATAG
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	TAAGACTTTCATATTGTTACCTCCTAGAATTTTTCTATTCCCT
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	TAAGACTTTGCAATCTTTGCCATGATCTTGGTCTTAGTGTTTT
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	TAAGACAGAACACGCATTTCAGTATCGAGCCTTTCCTTGTCA
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	TAAGACCATCACTCATCTTTTTGAGTACCTCTGCAGGTACATCA
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	GGCAACCTGGCGGTTGCCTGCTTGTCGGCTCGGTCATGCCCACGCAAGCGTGTTCGCGACGCTCGCCTCTGTCG
CAGTAAGACTTGGAACTCTCGCAAGAGAGAT	TAAGACGGAGCTGGTTCCCATTCAGCAGATTCAATTGCTGATC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATG

>NC_017448|3|1|2341980-2342385|CRT
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	TTAAACTCTTTTGTTGCTTTGAAGGGATTAAAATAG
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	TTTCATATTGTTACCTCCTAGAATTTTTCTATTCCCT
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	TTTGCAATCTTTGCCATGATCTTGGTCTTAGTGTTTT
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	AGAACACGCATTTCAGTATCGAGCCTTTCCTTGTCA
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	CATCACTCATCTTTTTGAGTACCTCTGCAGGTACATCA
CCCTGAAAAGCATTACTCTCGCAAGAGAGATGGCAAC

>NC_017448|3|4|2342053-2342310|PILER-CR
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	TTTCATATTGTTACCTCCTAGAATTTTTCTATTCCCT
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	TTTGCAATCTTTGCCATGATCTTGGTCTTAGTGTTTT
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	AGAACACGCATTTCAGTATCGAGCCTTTCCTTGTCA
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_014546229.1|2331591_2332188_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546228.1|2329165_2331412_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546229.1|2331591_2332188_+|hypothetical-protein
MKPKEFIDLFPFGYVRLRNQNGSVALSLDTPSTEAYVFARRKRRCDRMPPINQKEADLLQQEFGTDCTIVDWFSDDSCRYFITTSLEDALLHYRLVLSAFFDDETFEITGNFYEKKNENTRRKICYDRYLRKLPPDALTTEADFTKECYDVIFPDDALSHCRRLGNVIAMNTYCTPKANTHELENGKTLEDDDETDFD
>NC_017448.1|WP_014546228.1|2329165_2331412_+|hypothetical-protein
MATWNIGIDEKGRFGCFTESKEGPSVVCAFITQKNGADCEMFLKGCAALINRQKFDKVTNTVVREHYKNESDYDRAVFEKIVENFYHARAMRESGREKNDKKEDPLKETMDFLIDLEARKDFFEKIFVSPQNKDFVGSRQNYYLNSLYEVLSSVFESGIFKPKDSVNVYIAQRALEVIGYEFPADIVVRQLRNALENCASSEVSNDIENAIKIIHKYGDKQAHRSFESVGEEKDYKDLLKDYHDNLAKSIRNFLTSSYPNVSVGNVVCQSAKKYVFPAMADIAGTLVDYGVECEKAKKRSLVKGLNIKAFIEDGDFDAAAQLIGQLFYAPKKVKETLKGNLVELFISVTSEKDESITRKNYDSVWKILTDHCIGKMHNRGVEGELFLETGKLINLLDEFIDAYKPSPVVYARYLKMKGEFGQHSGSIDLDAAKGLAEKIKGFRENCRDKEVYAELYDLEEEFWIESCSQFRFNLYDFDDADYKQILKEYKLKMKRLPFWSEIYKKDDIKDRRYSVICGTIGQALAFSGDHKKAIEYLLEDYRHTNYMKNLPASFLVVEYLRKGELENAVEWFKNQVKEVLGKEKTIEQFFLDVEDGKKVDNWLVLNFLRIWAYSMKIGKPVVQRTLSFEKWTECNFDEYPGGLVLKWAAICNHYAKGSKETTVALLNKSIEVLTKESAFAVNSLALSPMRVLNVLDAMPIENYAKAFDDLCKRCESFAKYAKANPVLDPKTECKDVWDAAMILPFNYA
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE

Crispr_ID: NC_017448_5

• CRISPR_ID: NC_017448_5
• CRISPR_location: 2343839-2343944
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas1,cas2,csx1,cas10,csm3gr7,csx10gr5,csx19

Consensus repeat of NC_017448_5

Consensus_repeat	Method
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	CRISPRCasFinder

spacers of NC_017448_5

>5.1|2343870|44|NC_017448|CRISPRCasFinder
TAAGACTTTTCTAGCCCCTCCGCTATATGCTTTTCGAACCTTTC

CRISPR arrays and Neighbor proteins around NC_017448_5

CRISPR arrays

The CRISPR arrays of NC_017448_5

>merge|NC_017448|5|2343839-2343944|CRISPRCasFinder
GCGATAGAATCCATACTCTCGCAAGAGAGATTAAGACTTTTCTAGCCCCTCCGCTATATGCTTTTCGAACCTTTCCCCTGAAAAGCATTCCTCTCGCAAGAGAGAT

>NC_017448|5|4|2343839-2343944|CRISPRCasFinder
GCGATAGAATCCATACTCTCGCAAGAGAGAT	TAAGACTTTTCTAGCCCCTCCGCTATATGCTTTTCGAACCTTTC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_014546229.1|2331591_2332188_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546228.1|2329165_2331412_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546229.1|2331591_2332188_+|hypothetical-protein
MKPKEFIDLFPFGYVRLRNQNGSVALSLDTPSTEAYVFARRKRRCDRMPPINQKEADLLQQEFGTDCTIVDWFSDDSCRYFITTSLEDALLHYRLVLSAFFDDETFEITGNFYEKKNENTRRKICYDRYLRKLPPDALTTEADFTKECYDVIFPDDALSHCRRLGNVIAMNTYCTPKANTHELENGKTLEDDDETDFD
>NC_017448.1|WP_014546228.1|2329165_2331412_+|hypothetical-protein
MATWNIGIDEKGRFGCFTESKEGPSVVCAFITQKNGADCEMFLKGCAALINRQKFDKVTNTVVREHYKNESDYDRAVFEKIVENFYHARAMRESGREKNDKKEDPLKETMDFLIDLEARKDFFEKIFVSPQNKDFVGSRQNYYLNSLYEVLSSVFESGIFKPKDSVNVYIAQRALEVIGYEFPADIVVRQLRNALENCASSEVSNDIENAIKIIHKYGDKQAHRSFESVGEEKDYKDLLKDYHDNLAKSIRNFLTSSYPNVSVGNVVCQSAKKYVFPAMADIAGTLVDYGVECEKAKKRSLVKGLNIKAFIEDGDFDAAAQLIGQLFYAPKKVKETLKGNLVELFISVTSEKDESITRKNYDSVWKILTDHCIGKMHNRGVEGELFLETGKLINLLDEFIDAYKPSPVVYARYLKMKGEFGQHSGSIDLDAAKGLAEKIKGFRENCRDKEVYAELYDLEEEFWIESCSQFRFNLYDFDDADYKQILKEYKLKMKRLPFWSEIYKKDDIKDRRYSVICGTIGQALAFSGDHKKAIEYLLEDYRHTNYMKNLPASFLVVEYLRKGELENAVEWFKNQVKEVLGKEKTIEQFFLDVEDGKKVDNWLVLNFLRIWAYSMKIGKPVVQRTLSFEKWTECNFDEYPGGLVLKWAAICNHYAKGSKETTVALLNKSIEVLTKESAFAVNSLALSPMRVLNVLDAMPIENYAKAFDDLCKRCESFAKYAKANPVLDPKTECKDVWDAAMILPFNYA
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE

Crispr_ID: NC_017448_4

• CRISPR_ID: NC_017448_4
• CRISPR_location: 2343477-2343738
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas1,cas2,csx1,cas10,csm3gr7,csx10gr5,csx19

Consensus repeat of NC_017448_4

Consensus_repeat	Method
CCCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGACCACTACGC	PILER-CR
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	CRISPRCasFinder
CTCTCGCAAGAGAGATTAAGACC	CRT

spacers of NC_017448_4

>4.1|2343523|32|NC_017448|PILER-CR
TTGCTTCGCAGCGTTGCTTATGGAAGAGCGTA
>4.2|2343601|29|NC_017448|PILER-CR
TTATTATAGATAATGAAGTTCTTAGGTTC
>4.3|2343509|43|NC_017448|CRISPRCasFinder
TAAGACTACTTTGCTTCGCAGCGTTGCTTATGGAAGAGCGTAC
>4.4|2343583|44|NC_017448|CRISPRCasFinder
TAAGACCTCTACGCTTATTATAGATAATGAAGTTCTTAGGTTCT
>4.5|2343658|43|NC_017448|CRISPRCasFinder
TAAGACCCTTACGCCAGTAAAGTGCAGTGTTAACGTTAAACAA
>4.6|2343516|51|NC_017448|CRT
ACTTTGCTTCGCAGCGTTGCTTATGGAAGAGCGTACCCCTGAAAAGCATTA
>4.7|2343590|52|NC_017448|CRT
TCTACGCTTATTATAGATAATGAAGTTCTTAGGTTCTCCCTGAAAAGCATTA
>4.8|2343665|51|NC_017448|CRT
CTTACGCCAGTAAAGTGCAGTGTTAACGTTAAACAACCCTGAAAAGCATTC

CRISPR arrays and Neighbor proteins around NC_017448_4

CRISPR arrays

The CRISPR arrays of NC_017448_4

>merge|NC_017448|4|2343477-2343738|PILER-CR,CRISPRCasFinder,CRT
CCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACTACTTTGCTTCGCAGCGTTGCTTATGGAAGAGCGTACCCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGACCTCTACGCTTATTATAGATAATGAAGTTCTTAGGTTCTCCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGACCCTTACGCCAGTAAAGTGCAGTGTTAACGTTAAACAACCCTGAAAAGCATTCCTCTCGCAAGAGAGATGGCAACC

>NC_017448|4|5|2343477-2343671|PILER-CR
CCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACTACTTTGC	TTCGCAGCGTTGCTTATGGAAGAGCGTACCCC
TGAAAAGCATTACTCTCGCAAGAGAGATTAAGACCTCTACGCTTAT	TATAGATAATGAAGTTCTTAGGTTCTCCC
TGAAAAGCATTACTCTCGCAAGAGAGATTAAGACCCTTACGC

>NC_017448|4|3|2343478-2343732|CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGAT	TAAGACTACTTTGCTTCGCAGCGTTGCTTATGGAAGAGCGTAC
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	TAAGACCTCTACGCTTATTATAGATAATGAAGTTCTTAGGTTCT
CCCTGAAAAGCATTACTCTCGCAAGAGAGAT	TAAGACCCTTACGCCAGTAAAGTGCAGTGTTAACGTTAAACAA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATG

>NC_017448|4|2|2343493-2343738|CRT
CTCTCGCAAGAGAGATTAAGACT	ACTTTGCTTCGCAGCGTTGCTTATGGAAGAGCGTACCCCTGAAAAGCATTA
CTCTCGCAAGAGAGATTAAGACC	TCTACGCTTATTATAGATAATGAAGTTCTTAGGTTCTCCCTGAAAAGCATTA
CTCTCGCAAGAGAGATTAAGACC	CTTACGCCAGTAAAGTGCAGTGTTAACGTTAAACAACCCTGAAAAGCATTC
CTCTCGCAAGAGAGATGGCAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_014546229.1|2331591_2332188_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546228.1|2329165_2331412_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546229.1|2331591_2332188_+|hypothetical-protein
MKPKEFIDLFPFGYVRLRNQNGSVALSLDTPSTEAYVFARRKRRCDRMPPINQKEADLLQQEFGTDCTIVDWFSDDSCRYFITTSLEDALLHYRLVLSAFFDDETFEITGNFYEKKNENTRRKICYDRYLRKLPPDALTTEADFTKECYDVIFPDDALSHCRRLGNVIAMNTYCTPKANTHELENGKTLEDDDETDFD
>NC_017448.1|WP_014546228.1|2329165_2331412_+|hypothetical-protein
MATWNIGIDEKGRFGCFTESKEGPSVVCAFITQKNGADCEMFLKGCAALINRQKFDKVTNTVVREHYKNESDYDRAVFEKIVENFYHARAMRESGREKNDKKEDPLKETMDFLIDLEARKDFFEKIFVSPQNKDFVGSRQNYYLNSLYEVLSSVFESGIFKPKDSVNVYIAQRALEVIGYEFPADIVVRQLRNALENCASSEVSNDIENAIKIIHKYGDKQAHRSFESVGEEKDYKDLLKDYHDNLAKSIRNFLTSSYPNVSVGNVVCQSAKKYVFPAMADIAGTLVDYGVECEKAKKRSLVKGLNIKAFIEDGDFDAAAQLIGQLFYAPKKVKETLKGNLVELFISVTSEKDESITRKNYDSVWKILTDHCIGKMHNRGVEGELFLETGKLINLLDEFIDAYKPSPVVYARYLKMKGEFGQHSGSIDLDAAKGLAEKIKGFRENCRDKEVYAELYDLEEEFWIESCSQFRFNLYDFDDADYKQILKEYKLKMKRLPFWSEIYKKDDIKDRRYSVICGTIGQALAFSGDHKKAIEYLLEDYRHTNYMKNLPASFLVVEYLRKGELENAVEWFKNQVKEVLGKEKTIEQFFLDVEDGKKVDNWLVLNFLRIWAYSMKIGKPVVQRTLSFEKWTECNFDEYPGGLVLKWAAICNHYAKGSKETTVALLNKSIEVLTKESAFAVNSLALSPMRVLNVLDAMPIENYAKAFDDLCKRCESFAKYAKANPVLDPKTECKDVWDAAMILPFNYA
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE

Crispr_ID: NC_017448_6

• CRISPR_ID: NC_017448_6
• CRISPR_location: 2346087-2346190
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas2,cas1,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

Consensus repeat of NC_017448_6

Consensus_repeat	Method
CCCTGAAAAGCATTACTCTCGCAAGAGAGATT	CRISPRCasFinder

spacers of NC_017448_6

>6.1|2346119|39|NC_017448|CRISPRCasFinder
AAGACGTCGATCCTTCTTTTGGCCCCAACCTTCTTCTCC

CRISPR arrays and Neighbor proteins around NC_017448_6

CRISPR arrays

The CRISPR arrays of NC_017448_6

>merge|NC_017448|6|2346087-2346190|CRISPRCasFinder
CCCTGAAAAGTATTCCTCTCGCAAGAGAGATTAAGACGTCGATCCTTCTTTTGGCCCCAACCTTCTTCTCCCCCTGAAAAGTATTCCTCTCGCAAGAGAGATTG

>NC_017448|6|5|2346087-2346190|CRISPRCasFinder
CCCTGAAAAGTATTCCTCTCGCAAGAGAGATT	AAGACGTCGATCCTTCTTTTGGCCCCAACCTTCTTCTCC
CCCTGAAAAGTATTCCTCTCGCAAGAGAGATTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.7e-78	259.2	11.3
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	6.8e-56	182.8	0.0
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.50994e-70
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE
>NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MTVKAPFNFVPVSDKVYFPEWASYISHDIPFEDGVSGSIKVKITAKSPIFVRNGHTQGDADEISDAYKQFSNVDGKYYIPGTSIKGAVRSVLEIMSFGKMSTQETHKFAHREWDYKELYQIKGSLLKLRCGWLRRKSDGTYCVQSCGKPWRISFKDLDKYLGKNLFEQNFSNANKKSTDLNTAQKDAQKRGHFEEDPKSAMFKYRFFDDLKKTRDGIHFATIPPKEGKPDKRKVRIDENGEMVGSIVLTGQPDVSGFIDRKQGDGKFYEFVFQDKPEKNYPISEEMFKDLAYIYKDNPEWAYHAKNLETKGIPVFFREEGFGDRAKLVDCGLAYMYKQPFTKSPADWIPSAHNSNNHDLAESIFGYIAKEKDKPSLKGRVQFGHAFSKVTTGCKKDTEFVLANPRASYYPLYASDGSWDDANSIAGRKRYVVRTGEYGVADSVGTDNMKSMANVLNAGAIFEETITFHNLKHIELGALLSALTFHNNATCLHSIGQGKPFGWGATSFEIEELVVEGDREKDCLKYMGEFENAMDDFLGSAWVDDADIKELCAMATPIPTEANSTFEYMKLDNGGVNEFNKQPARCENLDRFTKIASLKKWNNWQMAKPNSIVNMPSDEKEKILADMEMRIQESLAKEAEYAAERAAVEQERREEEQKKAAKKANMDLSFLNTLTTFKDGKNRLEASFKKLDLLPITPDVLDHLSDEARQCIENFVARMFARPEKKWGSKNKDVAKDAAIAEVKKWFGSDYKCQGL
>NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein
MPRLFNVTNHSVTDDQRADAIASLGVGDVVDMPPDIARCWGTVPPELDSVCGYVQPVIDWLSSQATKGDVVWVQGEWGAVITVVAWCEARDLRAVYATTKREATEIHGENGVQMTHVFRHVRFRDFPKLGAR

Crispr_ID: NC_017448_7

• CRISPR_ID: NC_017448_7
• CRISPR_location: 2347309-2347415
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas2,cas1,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

Consensus repeat of NC_017448_7

Consensus_repeat	Method
CCCTGAAAAGCATTACTCTCGCAAGAGAGATT	CRISPRCasFinder

spacers of NC_017448_7

>7.1|2347341|42|NC_017448|CRISPRCasFinder
AAGACTGAAGATTATTAGTCACGATAGTATGACGTTATTATC

CRISPR arrays and Neighbor proteins around NC_017448_7

CRISPR arrays

The CRISPR arrays of NC_017448_7

>merge|NC_017448|7|2347309-2347415|CRISPRCasFinder
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGACTGAAGATTATTAGTCACGATAGTATGACGTTATTATCCCCTGAAAAGCATTACTCTCGCAAGAGAGATTG

>NC_017448|7|6|2347309-2347415|CRISPRCasFinder
CCCTGAAAAGCATTACTCTCGCAAGAGAGATT	AAGACTGAAGATTATTAGTCACGATAGTATGACGTTATTATC
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.7e-78	259.2	11.3
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	6.8e-56	182.8	0.0
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.50994e-70
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE
>NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MTVKAPFNFVPVSDKVYFPEWASYISHDIPFEDGVSGSIKVKITAKSPIFVRNGHTQGDADEISDAYKQFSNVDGKYYIPGTSIKGAVRSVLEIMSFGKMSTQETHKFAHREWDYKELYQIKGSLLKLRCGWLRRKSDGTYCVQSCGKPWRISFKDLDKYLGKNLFEQNFSNANKKSTDLNTAQKDAQKRGHFEEDPKSAMFKYRFFDDLKKTRDGIHFATIPPKEGKPDKRKVRIDENGEMVGSIVLTGQPDVSGFIDRKQGDGKFYEFVFQDKPEKNYPISEEMFKDLAYIYKDNPEWAYHAKNLETKGIPVFFREEGFGDRAKLVDCGLAYMYKQPFTKSPADWIPSAHNSNNHDLAESIFGYIAKEKDKPSLKGRVQFGHAFSKVTTGCKKDTEFVLANPRASYYPLYASDGSWDDANSIAGRKRYVVRTGEYGVADSVGTDNMKSMANVLNAGAIFEETITFHNLKHIELGALLSALTFHNNATCLHSIGQGKPFGWGATSFEIEELVVEGDREKDCLKYMGEFENAMDDFLGSAWVDDADIKELCAMATPIPTEANSTFEYMKLDNGGVNEFNKQPARCENLDRFTKIASLKKWNNWQMAKPNSIVNMPSDEKEKILADMEMRIQESLAKEAEYAAERAAVEQERREEEQKKAAKKANMDLSFLNTLTTFKDGKNRLEASFKKLDLLPITPDVLDHLSDEARQCIENFVARMFARPEKKWGSKNKDVAKDAAIAEVKKWFGSDYKCQGL
>NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein
MPRLFNVTNHSVTDDQRADAIASLGVGDVVDMPPDIARCWGTVPPELDSVCGYVQPVIDWLSSQATKGDVVWVQGEWGAVITVVAWCEARDLRAVYATTKREATEIHGENGVQMTHVFRHVRFRDFPKLGAR

Crispr_ID: NC_017448_8

• CRISPR_ID: NC_017448_8
• CRISPR_location: 2347561-2347770
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: cas2,cas1,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

Consensus repeat of NC_017448_8

Consensus_repeat	Method
CCCTGAAAAGCATTACTCTCGCAAGAGAGATT	CRISPRCasFinder

spacers of NC_017448_8

>8.1|2347593|73|NC_017448|CRISPRCasFinder
GCAACCTGGCGGTTGCCTGCTTGTCGGCTCGGTCATGCCCACGCAAGCGTGTTCGCGACACTCGCCTCTGTCG
>8.2|2347698|41|NC_017448|CRISPRCasFinder
AAGACTTTATTCTCAGGAGGCGGAATTCAGCTGTTATCCCG

CRISPR arrays and Neighbor proteins around NC_017448_8

CRISPR arrays

The CRISPR arrays of NC_017448_8

>merge|NC_017448|8|2347561-2347770|CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTGCAACCTGGCGGTTGCCTGCTTGTCGGCTCGGTCATGCCCACGCAAGCGTGTTCGCGACACTCGCCTCTGTCGCAGTAAGACTTAGAACTCTCGCAAGAGAGATTAAGACTTTATTCTCAGGAGGCGGAATTCAGCTGTTATCCCGCCCTGAAATGCATTACTCTCGTAAGAGAGATT

>NC_017448|8|7|2347561-2347770|CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATT	GCAACCTGGCGGTTGCCTGCTTGTCGGCTCGGTCATGCCCACGCAAGCGTGTTCGCGACACTCGCCTCTGTCG
CAGTAAGACTTAGAACTCTCGCAAGAGAGATT	AAGACTTTATTCTCAGGAGGCGGAATTCAGCTGTTATCCCG
CCCTGAAATGCATTACTCTCGTAAGAGAGATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.7e-78	259.2	11.3
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	6.8e-56	182.8	0.0
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.50994e-70
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE
>NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MTVKAPFNFVPVSDKVYFPEWASYISHDIPFEDGVSGSIKVKITAKSPIFVRNGHTQGDADEISDAYKQFSNVDGKYYIPGTSIKGAVRSVLEIMSFGKMSTQETHKFAHREWDYKELYQIKGSLLKLRCGWLRRKSDGTYCVQSCGKPWRISFKDLDKYLGKNLFEQNFSNANKKSTDLNTAQKDAQKRGHFEEDPKSAMFKYRFFDDLKKTRDGIHFATIPPKEGKPDKRKVRIDENGEMVGSIVLTGQPDVSGFIDRKQGDGKFYEFVFQDKPEKNYPISEEMFKDLAYIYKDNPEWAYHAKNLETKGIPVFFREEGFGDRAKLVDCGLAYMYKQPFTKSPADWIPSAHNSNNHDLAESIFGYIAKEKDKPSLKGRVQFGHAFSKVTTGCKKDTEFVLANPRASYYPLYASDGSWDDANSIAGRKRYVVRTGEYGVADSVGTDNMKSMANVLNAGAIFEETITFHNLKHIELGALLSALTFHNNATCLHSIGQGKPFGWGATSFEIEELVVEGDREKDCLKYMGEFENAMDDFLGSAWVDDADIKELCAMATPIPTEANSTFEYMKLDNGGVNEFNKQPARCENLDRFTKIASLKKWNNWQMAKPNSIVNMPSDEKEKILADMEMRIQESLAKEAEYAAERAAVEQERREEEQKKAAKKANMDLSFLNTLTTFKDGKNRLEASFKKLDLLPITPDVLDHLSDEARQCIENFVARMFARPEKKWGSKNKDVAKDAAIAEVKKWFGSDYKCQGL
>NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein
MPRLFNVTNHSVTDDQRADAIASLGVGDVVDMPPDIARCWGTVPPELDSVCGYVQPVIDWLSSQATKGDVVWVQGEWGAVITVVAWCEARDLRAVYATTKREATEIHGENGVQMTHVFRHVRFRDFPKLGAR

Crispr_ID: NC_017448_9

• CRISPR_ID: NC_017448_9
• CRISPR_location: 2348830-2349493
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 8 spacers
• Cas_protein_info: cas2,cas1,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

Consensus repeat of NC_017448_9

Consensus_repeat	Method
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	PILER-CR
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CRT

spacers of NC_017448_9

>9.1|2348867|37|NC_017448|PILER-CR,CRISPRCasFinder,CRT
TCATTACGAGCCAGAGCTGTCATCGGGCCGAGGTTCC
>9.2|2348941|36|NC_017448|PILER-CR,CRISPRCasFinder,CRT
TTGAGTCTGATTCCATTTTCATAGAAGAGACTTTCG
>9.3|2349014|37|NC_017448|PILER-CR,CRISPRCasFinder,CRT
GCACTTGATTTAAAGTTAACATTCTTTACAAATGCAA
>9.4|2349088|36|NC_017448|PILER-CR,CRISPRCasFinder,CRT
TAACTCCTTCAGATCCTTTAAGAAGGAATTCTTTCC
>9.5|2349161|37|NC_017448|PILER-CR,CRISPRCasFinder,CRT
TCCCCACATGCGGATCTTCTCATTGAGAAAATCGTCA
>9.6|2349235|39|NC_017448|CRISPRCasFinder,CRT
CCAGATGTAAAGTAGCCGTAAGCGAATCCACCACTATGT
>9.7|2349311|68|NC_017448|CRISPRCasFinder
CTAGCGGCTGCCTGCTTGTCGGCTCGGAAATGGTCCCGCAAGCGGTCCCGCTTCGCTCGCCTCTGTCG
>9.8|2349416|40|NC_017448|CRISPRCasFinder
TGAAATTTCACCTGGGCATACGGTACTCATAATTATTTGC

CRISPR arrays and Neighbor proteins around NC_017448_9

CRISPR arrays

The CRISPR arrays of NC_017448_9

>merge|NC_017448|9|2348830-2349493|PILER-CR,CRISPRCasFinder,CRT
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACTCATTACGAGCCAGAGCTGTCATCGGGCCGAGGTTCCCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACTTGAGTCTGATTCCATTTTCATAGAAGAGACTTTCGCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACGCACTTGATTTAAAGTTAACATTCTTTACAAATGCAACCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACTAACTCCTTCAGATCCTTTAAGAAGGAATTCTTTCCCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACTCCCCACATGCGGATCTTCTCATTGAGAAAATCGTCACCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACCCAGATGTAAAGTAGCCGTAAGCGAATCCACCACTATGTCCCTGAAAAGCATTACTCTCGCAAGAGAGATGGCAGCCTAGCGGCTGCCTGCTTGTCGGCTCGGAAATGGTCCCGCAAGCGGTCCCGCTTCGCTCGCCTCTGTCGCAGTAAGACCTGGAACTCTCGCAAGAGAGCTTAAGACTGAAATTTCACCTGGGCATACGGTACTCATAATTATTTGCCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTGCAGCC

>NC_017448|9|6|2348830-2349234|PILER-CR
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TCATTACGAGCCAGAGCTGTCATCGGGCCGAGGTTCC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TTGAGTCTGATTCCATTTTCATAGAAGAGACTTTCG
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	GCACTTGATTTAAAGTTAACATTCTTTACAAATGCAA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TAACTCCTTCAGATCCTTTAAGAAGGAATTCTTTCC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TCCCCACATGCGGATCTTCTCATTGAGAAAATCGTCA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC

>NC_017448|9|8|2348830-2349493|CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TCATTACGAGCCAGAGCTGTCATCGGGCCGAGGTTCC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TTGAGTCTGATTCCATTTTCATAGAAGAGACTTTCG
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	GCACTTGATTTAAAGTTAACATTCTTTACAAATGCAA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TAACTCCTTCAGATCCTTTAAGAAGGAATTCTTTCC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TCCCCACATGCGGATCTTCTCATTGAGAAAATCGTCA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CCAGATGTAAAGTAGCCGTAAGCGAATCCACCACTATGT
CCCTGAAAAGCATTACTCTCGCAAGAGAGATGGCAGC	CTAGCGGCTGCCTGCTTGTCGGCTCGGAAATGGTCCCGCAAGCGGTCCCGCTTCGCTCGCCTCTGTCG
CAGTAAGACCTGGAACTCTCGCAAGAGAGCTTAAGAC	TGAAATTTCACCTGGGCATACGGTACTCATAATTATTTGC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTGCAGCC

>NC_017448|9|3|2348830-2349310|CRT
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TCATTACGAGCCAGAGCTGTCATCGGGCCGAGGTTCC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TTGAGTCTGATTCCATTTTCATAGAAGAGACTTTCG
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	GCACTTGATTTAAAGTTAACATTCTTTACAAATGCAA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TAACTCCTTCAGATCCTTTAAGAAGGAATTCTTTCC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TCCCCACATGCGGATCTTCTCATTGAGAAAATCGTCA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CCAGATGTAAAGTAGCCGTAAGCGAATCCACCACTATGT
CCCTGAAAAGCATTACTCTCGCAAGAGAGATGGCAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.7e-78	259.2	11.3
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	6.8e-56	182.8	0.0
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.50994e-70
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE
>NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MTVKAPFNFVPVSDKVYFPEWASYISHDIPFEDGVSGSIKVKITAKSPIFVRNGHTQGDADEISDAYKQFSNVDGKYYIPGTSIKGAVRSVLEIMSFGKMSTQETHKFAHREWDYKELYQIKGSLLKLRCGWLRRKSDGTYCVQSCGKPWRISFKDLDKYLGKNLFEQNFSNANKKSTDLNTAQKDAQKRGHFEEDPKSAMFKYRFFDDLKKTRDGIHFATIPPKEGKPDKRKVRIDENGEMVGSIVLTGQPDVSGFIDRKQGDGKFYEFVFQDKPEKNYPISEEMFKDLAYIYKDNPEWAYHAKNLETKGIPVFFREEGFGDRAKLVDCGLAYMYKQPFTKSPADWIPSAHNSNNHDLAESIFGYIAKEKDKPSLKGRVQFGHAFSKVTTGCKKDTEFVLANPRASYYPLYASDGSWDDANSIAGRKRYVVRTGEYGVADSVGTDNMKSMANVLNAGAIFEETITFHNLKHIELGALLSALTFHNNATCLHSIGQGKPFGWGATSFEIEELVVEGDREKDCLKYMGEFENAMDDFLGSAWVDDADIKELCAMATPIPTEANSTFEYMKLDNGGVNEFNKQPARCENLDRFTKIASLKKWNNWQMAKPNSIVNMPSDEKEKILADMEMRIQESLAKEAEYAAERAAVEQERREEEQKKAAKKANMDLSFLNTLTTFKDGKNRLEASFKKLDLLPITPDVLDHLSDEARQCIENFVARMFARPEKKWGSKNKDVAKDAAIAEVKKWFGSDYKCQGL
>NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein
MPRLFNVTNHSVTDDQRADAIASLGVGDVVDMPPDIARCWGTVPPELDSVCGYVQPVIDWLSSQATKGDVVWVQGEWGAVITVVAWCEARDLRAVYATTKREATEIHGENGVQMTHVFRHVRFRDFPKLGAR

Crispr_ID: NC_017448_10

• CRISPR_ID: NC_017448_10
• CRISPR_location: 2349668-2349777
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas2,cas1,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

Consensus repeat of NC_017448_10

Consensus_repeat	Method
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CRISPRCasFinder

spacers of NC_017448_10

>10.1|2349705|35|NC_017448|CRISPRCasFinder
TTACGTCTGTAGAGACTTTTAATCCATCTCATATC

CRISPR arrays and Neighbor proteins around NC_017448_10

CRISPR arrays

The CRISPR arrays of NC_017448_10

>merge|NC_017448|10|2349668-2349777|CRISPRCasFinder
TGTAAGACACTTTAACTCTCGCAAGAGAGATTAAGACTTACGTCTGTAGAGACTTTTAATCCATCTCATATCCCCTGAAAAGCATTCCTCTCGCAAGAGAGATCTTTTTT

>NC_017448|10|9|2349668-2349777|CRISPRCasFinder
TGTAAGACACTTTAACTCTCGCAAGAGAGATTAAGAC	TTACGTCTGTAGAGACTTTTAATCCATCTCATATC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATCTTTTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.7e-78	259.2	11.3
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	6.8e-56	182.8	0.0
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.50994e-70
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE
>NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MTVKAPFNFVPVSDKVYFPEWASYISHDIPFEDGVSGSIKVKITAKSPIFVRNGHTQGDADEISDAYKQFSNVDGKYYIPGTSIKGAVRSVLEIMSFGKMSTQETHKFAHREWDYKELYQIKGSLLKLRCGWLRRKSDGTYCVQSCGKPWRISFKDLDKYLGKNLFEQNFSNANKKSTDLNTAQKDAQKRGHFEEDPKSAMFKYRFFDDLKKTRDGIHFATIPPKEGKPDKRKVRIDENGEMVGSIVLTGQPDVSGFIDRKQGDGKFYEFVFQDKPEKNYPISEEMFKDLAYIYKDNPEWAYHAKNLETKGIPVFFREEGFGDRAKLVDCGLAYMYKQPFTKSPADWIPSAHNSNNHDLAESIFGYIAKEKDKPSLKGRVQFGHAFSKVTTGCKKDTEFVLANPRASYYPLYASDGSWDDANSIAGRKRYVVRTGEYGVADSVGTDNMKSMANVLNAGAIFEETITFHNLKHIELGALLSALTFHNNATCLHSIGQGKPFGWGATSFEIEELVVEGDREKDCLKYMGEFENAMDDFLGSAWVDDADIKELCAMATPIPTEANSTFEYMKLDNGGVNEFNKQPARCENLDRFTKIASLKKWNNWQMAKPNSIVNMPSDEKEKILADMEMRIQESLAKEAEYAAERAAVEQERREEEQKKAAKKANMDLSFLNTLTTFKDGKNRLEASFKKLDLLPITPDVLDHLSDEARQCIENFVARMFARPEKKWGSKNKDVAKDAAIAEVKKWFGSDYKCQGL
>NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein
MPRLFNVTNHSVTDDQRADAIASLGVGDVVDMPPDIARCWGTVPPELDSVCGYVQPVIDWLSSQATKGDVVWVQGEWGAVITVVAWCEARDLRAVYATTKREATEIHGENGVQMTHVFRHVRFRDFPKLGAR

Crispr_ID: NC_017448_11

• CRISPR_ID: NC_017448_11
• CRISPR_location: 2350542-2351131
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 7 spacers
• Cas_protein_info: cas2,cas1,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

Consensus repeat of NC_017448_11

Consensus_repeat	Method
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	PILER-CR
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CRT

spacers of NC_017448_11

>11.1|2350579|36|NC_017448|PILER-CR,CRISPRCasFinder,CRT
TGAGATCAATTTGATGGTTAATCTTATCCATCTCGT
>11.2|2350652|39|NC_017448|PILER-CR,CRISPRCasFinder,CRT
CGTATACTCTTCTTGGTGCAAAGAAGAAGGAAAATACGG
>11.3|2350728|38|NC_017448|PILER-CR,CRISPRCasFinder,CRT
TCAAAGAATTTAGCTATAAGAGGTAACTGATCCCAATA
>11.4|2350803|38|NC_017448|PILER-CR,CRISPRCasFinder,CRT
CCTCAGCTTGCGAGTCATACTCTACAAGAGAATTCGTA
>11.5|2350878|38|NC_017448|CRISPRCasFinder,CRT
CTTCAGCTTGCGAGTCATACTCTACAAGAGAATTCGTA
>11.6|2350953|68|NC_017448|CRISPRCasFinder
CTGGCGGTTGCCTGCTTGTCGGCTCGGAAATGGTCCCGCAAGCGGTCCCGCTTCACTCGCCTCTGTCG
>11.7|2351058|36|NC_017448|CRISPRCasFinder
TCCTGAGAAGTTTGGTTAGACGGACGCTGCTTGAAA

CRISPR arrays and Neighbor proteins around NC_017448_11

CRISPR arrays

The CRISPR arrays of NC_017448_11

>merge|NC_017448|11|2350542-2351131|PILER-CR,CRISPRCasFinder,CRT
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACTGAGATCAATTTGATGGTTAATCTTATCCATCTCGTCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACCGTATACTCTTCTTGGTGCAAAGAAGAAGGAAAATACGGCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACTCAAAGAATTTAGCTATAAGAGGTAACTGATCCCAATACCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACCCTCAGCTTGCGAGTCATACTCTACAAGAGAATTCGTACCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACCTTCAGCTTGCGAGTCATACTCTACAAGAGAATTCGTACCCTGAAAAGCATTCCTCTCGCAAGAGAGATGGCAACCTGGCGGTTGCCTGCTTGTCGGCTCGGAAATGGTCCCGCAAGCGGTCCCGCTTCACTCGCCTCTGTCGCAGTAAGACTTGGAGCTCTCGCAAGAGAGATTAAGACTCCTGAGAAGTTTGGTTAGACGGACGCTGCTTGAAACCCTGAAAAGCATTACTCTCGCAAGAGAGATTGCAACC

>NC_017448|11|7|2350542-2350877|PILER-CR
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TGAGATCAATTTGATGGTTAATCTTATCCATCTCGT
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CGTATACTCTTCTTGGTGCAAAGAAGAAGGAAAATACGG
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TCAAAGAATTTAGCTATAAGAGGTAACTGATCCCAATA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CCTCAGCTTGCGAGTCATACTCTACAAGAGAATTCGTA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC

>NC_017448|11|10|2350542-2351131|CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TGAGATCAATTTGATGGTTAATCTTATCCATCTCGT
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CGTATACTCTTCTTGGTGCAAAGAAGAAGGAAAATACGG
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TCAAAGAATTTAGCTATAAGAGGTAACTGATCCCAATA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CCTCAGCTTGCGAGTCATACTCTACAAGAGAATTCGTA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CTTCAGCTTGCGAGTCATACTCTACAAGAGAATTCGTA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATGGCAAC	CTGGCGGTTGCCTGCTTGTCGGCTCGGAAATGGTCCCGCAAGCGGTCCCGCTTCACTCGCCTCTGTCG
CAGTAAGACTTGGAGCTCTCGCAAGAGAGATTAAGAC	TCCTGAGAAGTTTGGTTAGACGGACGCTGCTTGAAA
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTGCAACC

>NC_017448|11|4|2350542-2350952|CRT
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TGAGATCAATTTGATGGTTAATCTTATCCATCTCGT
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CGTATACTCTTCTTGGTGCAAAGAAGAAGGAAAATACGG
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TCAAAGAATTTAGCTATAAGAGGTAACTGATCCCAATA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CCTCAGCTTGCGAGTCATACTCTACAAGAGAATTCGTA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CTTCAGCTTGCGAGTCATACTCTACAAGAGAATTCGTA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATGGCAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.7e-78	259.2	11.3
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	6.8e-56	182.8	0.0
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.50994e-70
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE
>NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MTVKAPFNFVPVSDKVYFPEWASYISHDIPFEDGVSGSIKVKITAKSPIFVRNGHTQGDADEISDAYKQFSNVDGKYYIPGTSIKGAVRSVLEIMSFGKMSTQETHKFAHREWDYKELYQIKGSLLKLRCGWLRRKSDGTYCVQSCGKPWRISFKDLDKYLGKNLFEQNFSNANKKSTDLNTAQKDAQKRGHFEEDPKSAMFKYRFFDDLKKTRDGIHFATIPPKEGKPDKRKVRIDENGEMVGSIVLTGQPDVSGFIDRKQGDGKFYEFVFQDKPEKNYPISEEMFKDLAYIYKDNPEWAYHAKNLETKGIPVFFREEGFGDRAKLVDCGLAYMYKQPFTKSPADWIPSAHNSNNHDLAESIFGYIAKEKDKPSLKGRVQFGHAFSKVTTGCKKDTEFVLANPRASYYPLYASDGSWDDANSIAGRKRYVVRTGEYGVADSVGTDNMKSMANVLNAGAIFEETITFHNLKHIELGALLSALTFHNNATCLHSIGQGKPFGWGATSFEIEELVVEGDREKDCLKYMGEFENAMDDFLGSAWVDDADIKELCAMATPIPTEANSTFEYMKLDNGGVNEFNKQPARCENLDRFTKIASLKKWNNWQMAKPNSIVNMPSDEKEKILADMEMRIQESLAKEAEYAAERAAVEQERREEEQKKAAKKANMDLSFLNTLTTFKDGKNRLEASFKKLDLLPITPDVLDHLSDEARQCIENFVARMFARPEKKWGSKNKDVAKDAAIAEVKKWFGSDYKCQGL
>NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein
MPRLFNVTNHSVTDDQRADAIASLGVGDVVDMPPDIARCWGTVPPELDSVCGYVQPVIDWLSSQATKGDVVWVQGEWGAVITVVAWCEARDLRAVYATTKREATEIHGENGVQMTHVFRHVRFRDFPKLGAR

Crispr_ID: NC_017448_12

• CRISPR_ID: NC_017448_12
• CRISPR_location: 2352033-2352322
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas2,cas1,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

Consensus repeat of NC_017448_12

Consensus_repeat	Method
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CRISPRCasFinder

spacers of NC_017448_12

>12.1|2352070|37|NC_017448|CRISPRCasFinder
AGTTATATTTGTCAAAGTCTGGAGGAAGTGTAGTTTT
>12.2|2352144|36|NC_017448|CRISPRCasFinder
CTTTCTAATTTCCTTACGGCGTCGTCTAGTGAATTC
>12.3|2352217|68|NC_017448|CRISPRCasFinder
CTGGCGGCTGCCTGCTTGTCGGCTCGGTCATGCCCGTGCAAGCACGGTCGCGACACTCGCCTCTGTCG

CRISPR arrays and Neighbor proteins around NC_017448_12

CRISPR arrays

The CRISPR arrays of NC_017448_12

>merge|NC_017448|12|2352033-2352322|CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACAGTTATATTTGTCAAAGTCTGGAGGAAGTGTAGTTTTCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACCTTTCTAATTTCCTTACGGCGTCGTCTAGTGAATTCCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTGCAACCTGGCGGCTGCCTGCTTGTCGGCTCGGTCATGCCCGTGCAAGCACGGTCGCGACACTCGCCTCTGTCGCAGTAAGACTTGGAGCTCTCGCAAGAGAGATTATGACC

>NC_017448|12|11|2352033-2352322|CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	AGTTATATTTGTCAAAGTCTGGAGGAAGTGTAGTTTT
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CTTTCTAATTTCCTTACGGCGTCGTCTAGTGAATTC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTGCAAC	CTGGCGGCTGCCTGCTTGTCGGCTCGGTCATGCCCGTGCAAGCACGGTCGCGACACTCGCCTCTGTCG
CAGTAAGACTTGGAGCTCTCGCAAGAGAGATTATGACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.7e-78	259.2	11.3
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	6.8e-56	182.8	0.0
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.50994e-70
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE
>NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MTVKAPFNFVPVSDKVYFPEWASYISHDIPFEDGVSGSIKVKITAKSPIFVRNGHTQGDADEISDAYKQFSNVDGKYYIPGTSIKGAVRSVLEIMSFGKMSTQETHKFAHREWDYKELYQIKGSLLKLRCGWLRRKSDGTYCVQSCGKPWRISFKDLDKYLGKNLFEQNFSNANKKSTDLNTAQKDAQKRGHFEEDPKSAMFKYRFFDDLKKTRDGIHFATIPPKEGKPDKRKVRIDENGEMVGSIVLTGQPDVSGFIDRKQGDGKFYEFVFQDKPEKNYPISEEMFKDLAYIYKDNPEWAYHAKNLETKGIPVFFREEGFGDRAKLVDCGLAYMYKQPFTKSPADWIPSAHNSNNHDLAESIFGYIAKEKDKPSLKGRVQFGHAFSKVTTGCKKDTEFVLANPRASYYPLYASDGSWDDANSIAGRKRYVVRTGEYGVADSVGTDNMKSMANVLNAGAIFEETITFHNLKHIELGALLSALTFHNNATCLHSIGQGKPFGWGATSFEIEELVVEGDREKDCLKYMGEFENAMDDFLGSAWVDDADIKELCAMATPIPTEANSTFEYMKLDNGGVNEFNKQPARCENLDRFTKIASLKKWNNWQMAKPNSIVNMPSDEKEKILADMEMRIQESLAKEAEYAAERAAVEQERREEEQKKAAKKANMDLSFLNTLTTFKDGKNRLEASFKKLDLLPITPDVLDHLSDEARQCIENFVARMFARPEKKWGSKNKDVAKDAAIAEVKKWFGSDYKCQGL
>NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein
MPRLFNVTNHSVTDDQRADAIASLGVGDVVDMPPDIARCWGTVPPELDSVCGYVQPVIDWLSSQATKGDVVWVQGEWGAVITVVAWCEARDLRAVYATTKREATEIHGENGVQMTHVFRHVRFRDFPKLGAR

Crispr_ID: NC_017448_14

• CRISPR_ID: NC_017448_14
• CRISPR_location: 2353489-2353599
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas2,cas1,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

Consensus repeat of NC_017448_14

Consensus_repeat	Method
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CRISPRCasFinder

spacers of NC_017448_14

>14.1|2353526|36|NC_017448|CRISPRCasFinder
AGAGTGAACTTGTTATTGTTTTCTTCAACCTTCTTC

CRISPR arrays and Neighbor proteins around NC_017448_14

CRISPR arrays

The CRISPR arrays of NC_017448_14

>merge|NC_017448|14|2353489-2353599|CRISPRCasFinder
CTGAAGATAAAAGACCTCTCGCAAGAGAGATTAAGACAGAGTGAACTTGTTATTGTTTTCTTCAACCTTCTTCCCCTGAAACGCATTCCTCTCGCAAGAGAGATTGCAACC

>NC_017448|14|13|2353489-2353599|CRISPRCasFinder
CTGAAGATAAAAGACCTCTCGCAAGAGAGATTAAGAC	AGAGTGAACTTGTTATTGTTTTCTTCAACCTTCTTC
CCCTGAAACGCATTCCTCTCGCAAGAGAGATTGCAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.7e-78	259.2	11.3
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	6.8e-56	182.8	0.0
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.50994e-70
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE
>NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MTVKAPFNFVPVSDKVYFPEWASYISHDIPFEDGVSGSIKVKITAKSPIFVRNGHTQGDADEISDAYKQFSNVDGKYYIPGTSIKGAVRSVLEIMSFGKMSTQETHKFAHREWDYKELYQIKGSLLKLRCGWLRRKSDGTYCVQSCGKPWRISFKDLDKYLGKNLFEQNFSNANKKSTDLNTAQKDAQKRGHFEEDPKSAMFKYRFFDDLKKTRDGIHFATIPPKEGKPDKRKVRIDENGEMVGSIVLTGQPDVSGFIDRKQGDGKFYEFVFQDKPEKNYPISEEMFKDLAYIYKDNPEWAYHAKNLETKGIPVFFREEGFGDRAKLVDCGLAYMYKQPFTKSPADWIPSAHNSNNHDLAESIFGYIAKEKDKPSLKGRVQFGHAFSKVTTGCKKDTEFVLANPRASYYPLYASDGSWDDANSIAGRKRYVVRTGEYGVADSVGTDNMKSMANVLNAGAIFEETITFHNLKHIELGALLSALTFHNNATCLHSIGQGKPFGWGATSFEIEELVVEGDREKDCLKYMGEFENAMDDFLGSAWVDDADIKELCAMATPIPTEANSTFEYMKLDNGGVNEFNKQPARCENLDRFTKIASLKKWNNWQMAKPNSIVNMPSDEKEKILADMEMRIQESLAKEAEYAAERAAVEQERREEEQKKAAKKANMDLSFLNTLTTFKDGKNRLEASFKKLDLLPITPDVLDHLSDEARQCIENFVARMFARPEKKWGSKNKDVAKDAAIAEVKKWFGSDYKCQGL
>NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein
MPRLFNVTNHSVTDDQRADAIASLGVGDVVDMPPDIARCWGTVPPELDSVCGYVQPVIDWLSSQATKGDVVWVQGEWGAVITVVAWCEARDLRAVYATTKREATEIHGENGVQMTHVFRHVRFRDFPKLGAR

Crispr_ID: NC_017448_13

• CRISPR_ID: NC_017448_13
• CRISPR_location: 2353162-2353348
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: cas2,cas1,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

Consensus repeat of NC_017448_13

Consensus_repeat	Method
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CRISPRCasFinder

spacers of NC_017448_13

>13.1|2353199|37|NC_017448|CRISPRCasFinder
GACGAATGCCCCACGTGCATCACCAAGTTTGTCTTCA
>13.2|2353273|38|NC_017448|CRISPRCasFinder
TTCCCCTATCTTTCCGTGGAAAGTCATTGTTTATTTTC

CRISPR arrays and Neighbor proteins around NC_017448_13

CRISPR arrays

The CRISPR arrays of NC_017448_13

>merge|NC_017448|13|2353162-2353348|CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACGACGAATGCCCCACGTGCATCACCAAGTTTGTCTTCACCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGACTTCCCCTATCTTTCCGTGGAAAGTCATTGTTTATTTTCCCCTGAAAAGCATTCCTCTCGCAAGAGAGATTGCAACC

>NC_017448|13|12|2353162-2353348|CRISPRCasFinder
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	GACGAATGCCCCACGTGCATCACCAAGTTTGTCTTCA
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	TTCCCCTATCTTTCCGTGGAAAGTCATTGTTTATTTTC
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTGCAACC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.7e-78	259.2	11.3
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	6.8e-56	182.8	0.0
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.50994e-70
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE
>NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MTVKAPFNFVPVSDKVYFPEWASYISHDIPFEDGVSGSIKVKITAKSPIFVRNGHTQGDADEISDAYKQFSNVDGKYYIPGTSIKGAVRSVLEIMSFGKMSTQETHKFAHREWDYKELYQIKGSLLKLRCGWLRRKSDGTYCVQSCGKPWRISFKDLDKYLGKNLFEQNFSNANKKSTDLNTAQKDAQKRGHFEEDPKSAMFKYRFFDDLKKTRDGIHFATIPPKEGKPDKRKVRIDENGEMVGSIVLTGQPDVSGFIDRKQGDGKFYEFVFQDKPEKNYPISEEMFKDLAYIYKDNPEWAYHAKNLETKGIPVFFREEGFGDRAKLVDCGLAYMYKQPFTKSPADWIPSAHNSNNHDLAESIFGYIAKEKDKPSLKGRVQFGHAFSKVTTGCKKDTEFVLANPRASYYPLYASDGSWDDANSIAGRKRYVVRTGEYGVADSVGTDNMKSMANVLNAGAIFEETITFHNLKHIELGALLSALTFHNNATCLHSIGQGKPFGWGATSFEIEELVVEGDREKDCLKYMGEFENAMDDFLGSAWVDDADIKELCAMATPIPTEANSTFEYMKLDNGGVNEFNKQPARCENLDRFTKIASLKKWNNWQMAKPNSIVNMPSDEKEKILADMEMRIQESLAKEAEYAAERAAVEQERREEEQKKAAKKANMDLSFLNTLTTFKDGKNRLEASFKKLDLLPITPDVLDHLSDEARQCIENFVARMFARPEKKWGSKNKDVAKDAAIAEVKKWFGSDYKCQGL
>NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein
MPRLFNVTNHSVTDDQRADAIASLGVGDVVDMPPDIARCWGTVPPELDSVCGYVQPVIDWLSSQATKGDVVWVQGEWGAVITVVAWCEARDLRAVYATTKREATEIHGENGVQMTHVFRHVRFRDFPKLGAR

Crispr_ID: NC_017448_15

• CRISPR_ID: NC_017448_15
• CRISPR_location: 2353677-2353925
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 3 spacers
• Cas_protein_info: cas2,cas1,csx1,cas10,csm3gr7,csx10gr5,csx19,csx20

Consensus repeat of NC_017448_15

Consensus_repeat	Method
GCATTACTCTCGCAAGAGAGATTAAGAC	CRT
CCCTGAAAAGCATTCCTCTCGCAAGAGAGATTAAGAC	CRISPRCasFinder

spacers of NC_017448_15

>15.1|2353705|46|NC_017448|CRT
ATAATTTCTGCTGCCTTATTTTCTACAGGGAATGACTCCCTGAAAG
>15.2|2353779|48|NC_017448|CRT
GTGATCAGTTCCGAACCTAATTCCGCAATAGAAGTCATCCCCTGAAAA
>15.3|2353855|43|NC_017448|CRT
TCAAGAATTTGGGGTCGAACGTCAATTTCCATAACCCTGAAAA
>15.4|2353779|39|NC_017448|CRISPRCasFinder
GTGATCAGTTCCGAACCTAATTCCGCAATAGAAGTCATC
>15.5|2353855|34|NC_017448|CRISPRCasFinder
TCAAGAATTTGGGGTCGAACGTCAATTTCCATAA

CRISPR arrays and Neighbor proteins around NC_017448_15

CRISPR arrays

The CRISPR arrays of NC_017448_15

>merge|NC_017448|15|2353677-2353925|CRT,CRISPRCasFinder
TGGAAATTCTCGCAAGAGAGATTAAGACATAATTTCTGCTGCCTTATTTTCTACAGGGAATGACTCCCTGAAAGGCATTACTCTCGCAAGAGAGATTAAGACGTGATCAGTTCCGAACCTAATTCCGCAATAGAAGTCATCCCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGACTCAAGAATTTGGGGTCGAACGTCAATTTCCATAACCCTGAAAAGCATTACTCTCGCAAGAGAGATGACAAT

>NC_017448|15|5|2353677-2353925|CRT
TGGAAATTCTCGCAAGAGAGATTAAGAC	ATAATTTCTGCTGCCTTATTTTCTACAGGGAATGACTCCCTGAAAG
GCATTACTCTCGCAAGAGAGATTAAGAC	GTGATCAGTTCCGAACCTAATTCCGCAATAGAAGTCATCCCCTGAAAA
GCATTACTCTCGCAAGAGAGATTAAGAC	TCAAGAATTTGGGGTCGAACGTCAATTTCCATAACCCTGAAAA
GCATTACTCTCGCAAGAGAGATGACAAT

>NC_017448|15|14|2353742-2353925|CRISPRCasFinder
CCCTGAAAGGCATTACTCTCGCAAGAGAGATTAAGAC	GTGATCAGTTCCGAACCTAATTCCGCAATAGAAGTCATC
CCCTGAAAAGCATTACTCTCGCAAGAGAGATTAAGAC	TCAAGAATTTGGGGTCGAACGTCAATTTCCATAA
CCCTGAAAAGCATTACTCTCGCAAGAGAGATGACAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	gnl|CDD|274040
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|376633
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	unknown	unknown	gnl|CDD|223609
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|226699
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|274902
NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238741
NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	unknown
NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	unknown	unknown	gnl|CDD|226124
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl|CDD|377130
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	unknown
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	gnl|CDD|275216
NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein	unknown	unknown	unknown
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	gnl|CDD|187810

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	csx1	cd09671_csx1_CAS-III	2e-78	258.8	0.3
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	4.7e-76	250.5	0.0
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	cas10	mkCas0133_cas10_CAS-III	8e-112	368.9	1.0
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	2.1e-21	71.0	0.3
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	2.7e-78	259.2	11.3
NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein	csx20	cls000023_csx20_CAS-I:CAS-III	6.8e-56	182.8	0.0
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	csx19	mkCas0144_csx19_CAS-III-D	3.5e-50	164.3	0.1
NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	1.3e-128	424.0	0.6
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-23	76.0	0.1
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.3e-39	129.5	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	3.70995e-76
NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1	gnl|CDD|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.1685e-99
NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein	gnl|CDD|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	3.69947e-14
NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	4.38437e-61
NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	3.44709e-31
NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl|CDD|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	6.50994e-70
NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein	gnl|CDD|238741	cd01464, vWA_subfamily, VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains. Members of this subgroup have no assigned function. This subfamily is typified by the presence of a conserved MIDAS motif.	2.49537e-62
NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.92452e-23
NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	1.10694e-20
NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	6.44291e-72
NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.00176e-44
NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein	gnl|CDD|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.89122e-12
NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein	gnl|CDD|275216	TIGR04423, predicted_protein, CRISPR type III-associated protein, TIGR04423 family. Members of this protein family occur only in species with CRISPR systems, in the context of type III systems that resemble type III-A (MTUBE) and III-B (the RAMP module). It occurs in several species of Prevotella, Helicobacter, Campylobacter, and Bacteroides.	5.24968e-55
NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	1.12868e-06

Protein sequences

>NC_017448.1|WP_014546238.1|2345554_2345830_+|CRISPR-associated-endonuclease-Cas2
MKYLVAFDISNSRRRGRMVKLCLATGFRVQKSVFESFLDSVQVASFENEAEKIIDPDTDSVRLYPIDARADEGVRIVGCGKRIENPAFKVL
>NC_017448.1|WP_014546237.1|2344526_2345558_+|CRISPR-associated-endonuclease-Cas1
MHLYVTEQGTRLGKNGGHLVVQRDGCTIDDILLSEVDSLSLFGAVHPTTDAMLALLDKGADIAFLSSGGRYRGRLVSAVGKNVPLRLCQYDVFRDDDRAFALAKSCVVRKLENGLRVLEAYSKNPHNSFRFENRDEYLRNLNAVRRLQGFDRDELRGFEGNGARIYFENFGRCLACGLDFPGRKYHPSTDPVNALLSFGYTLTARSLESLLESYGMDPMLGYLHEPSYGRNSLAQDMLEEFRHPLVDRLVLFLFNRRVLVADDFEQRNDENSSGQLFLKPEKMRVFLHHYEDFVARPNGIYQGLANLPWRSVMRLRVEAFRRLLLEGVEMADLQWNPEYSESA
>NC_017448.1|WP_014546236.1|2340249_2341266_+|50S-ribosome-binding-GTPase
MTYNTNNMEFVTKMEHDIEASGLPDAVKHKLLANLLLLKSKKVNLLITGATGCGKSSTINALFNADVSKVGVGVDPETMEIEKYELGNLVLWDSPGLGDGKEADNRHAKNLTAKLLERDADGNPLIDLVLVILDGSSRDMGTSFELISNVIVPNLGEDKSRILVAINQADMAMKGRGWDRVNNRPEPALEQFLQEKVESVRRRIKESTGVDVEPIYYSAGYKDGDAPQRPYNLTKLLYQIVHYTPKEKRTIYANNINRDREMWKDDDELKDYRNSILDDIVESISDCAETGAEIGESLGGLFGSAGRTVGRVAGRVVGGAFGAVKSIAKSFFGGLFGW
>NC_017448.1|WP_014546235.1|2339477_2340164_+|50S-ribosome-binding-GTPase
MQNFKNYRKYEISSRLGDNLPLDVMIVGATGAGKSSLVNALCGGAVACVGEGVDPETMDITRYALNNHFCVWDTPGLGDSAVADASHKRNIVKHLLKTYENGGARYRFMDLVLVVLEGGIRDMGSCYSLLNEVVVPNIDRERIVVAINQADIAMKGTHWDSWRNKPDAVLDSFLRDKAESVRRRVYEATGVSIRTPVCFSAGTGYNMDAVVDALIEQIPRYRPAVRHA
>NC_017448.1|WP_015732047.1|2337455_2339450_+|hypothetical-protein
MTQFKNLAAFTLFAVSLLASVVSAAGSNLFEFKSANVPPGSMAIEYYGALSGIYQGKDNLFFKGADTVHVYFVGELRDSKMVNGAAEIKDEERHVSYTGNIVNGVMQDDHAEATRVKSKKSMEFFSGSFNGYEFDSCFYANSGTSERYIGKMSNGKFNDVSASYVGPLYRIYNGDFSSYAIQSDFFDFSPVNFSRKDMATFQGAMRDGRIADFGSLSVVHKGDTLHYTGDFENAQVNGVGTVKVGDLYSYVGHFAKGLIAGLGEITSDHFSRLFTESEHVPAGTISIKGIWAGISGLGTYFRVTDEDGANVKLKMNDGTIEELSSLQRFRNWVSETGVSEWIVSHRSEIDKVITGAAFVDAGVCASLLIFPASAPVTGPICGGGFFTIVGTEAVLQLILTFDAINEQCYTEDCVEDLWKNFGKEQLFNAGLILLPPVIARAGKAVAPTLKSYLATVKEFGYTRAIAMSKNAQAVKELEMLPEISLPRVREIDVLNDRLAFKQAVVDYTGKSFRDGFVEFFVRLKKSGQENLIKDIWKSHKDFIKNSGIRAGGEHEWLEADRFVDYLLNPKWGSDGAYLAYILPRMTQRTTGVKFANGGAHTIVDETGRKIPGPNSGSFHKTLGETIGSCNTASCVFGKMKSFASRELTSSSYKEYLAMERAVLE
>NC_017448.1|WP_014546234.1|2336689_2337427_+|hypothetical-protein
MTTITTNSKIESLIESARKHGDSASINALYELYEEKFKSAAMYHFKRIPFNFDVARLPNSRYKQDLIISAAYDAFVKTYKTYDGSRGASFVTLLNRNIEWLFKDLQKENAKESKRWKNSTDAIYSKRKQDYTDDLENVSCSSRDAYDTCDTDMVNEVLSTMQGAARKNAEALYRIFSEEGADKQCSAADRLGISRQAINKSFKSYREYGPKAIRDRVLETLREKASQRVVGTKTTNCNVFKDESK
>NC_017448.1|WP_014546233.1|2335389_2336388_+|radical-SAM-protein
MIGLEGKDPMPTNAINFPKNFQNADSFARFAKVSPLVVNWHALEHCNYKCSFCYSDWNSRDEAWNTPENVRKVIENIARFHADYFGADAAPWRLSVVGGEPILFPKKAQFMVKTAVACGAEVSIITNGSHLENALPFAHLLSQVGISLDSFVHETNLKIGRQCNGHTLSFEEISDKIAALRAVNPNVRVKVNTVVNQNNFGEVLVDKVAALGATKYKILRQMPFGGNKGITDDEFHVFIRNNYREDLFGHDDGKRHIFIEDNSVMTQSYLMIAPNGCLFQNGGAEYRYSRPLMETPFEEALKDINFSAEKFFSRYTSTATDAILARMHECAA
>NC_017448.1|WP_014546232.1|2334122_2335124_+|protein-phosphatase-2C-domain-containing-protein
MCWVTVQSAVQGRGHLSSGTPCQDKTFSVIKDGCSVCALADGAGSASLSHFGAEAVTQTICNFMAENFDFVINEEDGVAVKQRILEVVGQRLNALCAERGCSLKDLASTLLFVAVKAGKFVICHIGDGVIGYFKNGEVLVASHPENGEFANTTVFTTSNNAIASMKLIKGNLNQISGFVLMSDGSENSFYNKRNKVLSPSLARLFKLASVCDGAFMSQGLRDALENCVKRKTTDDCSMVLMSQPANGRGFADLADTDKCEFLRLPDTRASRKRLKSFEDALDALRSWSSYRAAKRRLHWRGKKLDRILACLGKANLLQVREDGCYKSALRAFL
>NC_017448.1|WP_014546231.1|2333434_2334121_+|VWA-domain-containing-protein
MTNEKLLNIEDLENNPSTRVPVCLVLDTSGSMEGQPISELNEGINCFYDAVRSDETALYAAEIAVVTFGGSAVLKTDFSTLEHQPDSPNFFANGGTPMGEAMNMALDLLEKRKGEYKASGVDYYQPWIVLMTDGKPNGDSSEYARAVQRTCEMIKNRKLTIFPIGIGEDADMNALAAFSPKRSPLKLQGLNFREFFAWLSKSVSKVSQSTPGDKIQLDTDGIKGWAEL
>NC_017448.1|WP_014546230.1|2332168_2333383_+|serine/threonine-protein-kinase
MKPILINADKRLAVTRASRPGDLLHTPKGTSIRLVSVLGEGGEGAVYETNMPYVAKVYKPEKTTSHKLVKIQAMASAGVKFPGICLPLAPLYNSRNEFVGYLMEKADGVKIRTLYQKPLLQKKFPHWTKRDLVELCVTILEKIECLHRKGIVLGDINPDNILVKTPREVYFVDCDSYQVAGYPCPVGTIPFTPPELQNRGHYDSYLRTVGNENFAVAVLLFSLMITGQMPYNQKGGVSAQQNIIDMDFSYPLGESSNKKTPNGPWRFLWSHLPRFLKDAFYNTFNKGGNYSVESKRLSTFDWLKKFKEYLRLLDSGKLGEQDEMSTWIYPTRFKKQKGVVYVKCPYCKNDTDQSWINEKGACIECLRKRRLARQRSYGNPRVLQESKVQSPLNVLPDFLYRLFG
>NC_017448.1|WP_014546239.1|2354401_2354830_+|hypothetical-protein
MSILGKIKKFIIDIIGDADAVSVLISDCEVPDKEFEEGTKGYDNTLDAIADGKFGYRPEFDKLLRRYGRTFKGPKPNAKKYQESNVFTRTKKNAWLYDSINEALRQQAESAAQFSCDEEPKSFKEKIQKAEFVEVEIVDTER
>NC_017448.1|WP_155808761.1|2354846_2355059_-|hypothetical-protein
MIDKDEHNACLYTAIRISKEEGIAEGMAKGEAKGRAETKRKFAARDKKIAKFLQAHGVSAKLMTAAFAIK
>NC_017448.1|WP_014546240.1|2355372_2356671_+|TIGR02221-family-CRISPR-associated-protein
MSRKIFVSFLGLTDYKLAVYKSWRGEGCASETRFVQKAIVELYPKTDLDKIVIFVTKESREKNEQALLEDLKELGVEPEKIETELISVDVSDLSLTWNWFESLQSKFEKGDTLVLDVTHGFRMVPVVFSAAVAYLKRVKNVHLESVLYGAFEMKVDAKPIVNLKDFYTISDWTEGVGRLVDTADASFLRKTAESESNGSFAGLNNQDLLNSIDDLTKAFRNVELQNIESKARKSLDLICKFQKQSSGKLEGQVLQMIIDQFQPLVSEPPLDGSYSLDYLKLQLRLIKMFAEYNLYMQAFTAMNEWLGSLGVFLMKRGSEFRFTSREKDSSARSHAAVFLNMLQHPADFEAENETIAMLKASLDEAYNTLFEKYTTQDEISDLLKQSKKIRNGFNHGWTGVHRKGAPKDLNEKFDRAMATLNRIVEKIGDDNG
>NC_017448.1|WP_014546241.1|2356663_2358181_+|CRISPR-associated-protein
MAKFLYGAAVQGIQGFIFQTNKLRDIVGASELVERICTTDFDEFAESNGGANDPKSILRAAGNIKYLFESEDACKKAVLKFPKKVVENAPGITISQAVVPVEDDADIAAAIDKLEASLRVQRNRQMRPINLGFTGVLRSRSTGFPAVEVRKDKNGQDEFLDKATQKKRDASETQALSKKAFGFDVLTKQVAFEIDQITGKNDWIAVIHADGNGLGQVVQKVGKKTDEFKAFSKALDEATVGAAVDAFNALVERKYFDVKDESKLIPIRPVVLGGDDFTVICRADFAVEYVQKFLESFEKRTGEGVIAELLKKNAVFENGNKLTACAGIAFVKSSYPFYYAYDLAESLCSMAKKDAKKPENPRYLAPSCLMFHKVQSSFVESFDKIVDKELTASGCLYVFGPYYLAETPYRWTVDKLMEVCDLLDGEDGNALKSNVRQWLTLQSQDAGMAKQKAERIVSILEKSDLRSIAEELVQNEVLRNGKKYSPAYDVLSLHSVRFQETRSAK
>NC_017448.1|WP_014546242.1|2358192_2358744_+|CRISPR-associated-RAMP-protein
MNINYTIQFFSGWHCGSGLSAGADVDTLVVKDDDGLPFVPGKTIKGLLREAVEDYAALTQEVSAERIDAVFGSFDSKEKFSRGVAFFGNAALSDDEAKAIKSDKLQPFLYKRLSATAIGENGVAKDHSLRRIEVVVPCKLQGKILDIPEDFVEVLKKSMGLIKRLGSWRNRGLGRCTFKCEGC
>NC_017448.1|WP_041260151.1|2358746_2360222_+|hypothetical-protein
MSTLKFKCTLLTDVILNQHAATEGNQSTLDFIPGNNFLGIVAGNVYAEHRDLALDILHSGKVRFGDAHPALNGVRSLRVPSCFFYPKLGSYKEECYVHHGIPNLASDDLKKKQLKQCRNGFLAFNDSKSSFTDVVPEKFFAIKSAHDREKFRSKDSQMYGYESLRKGLELFFEVEVDDSLTTDVKELVSSLLVGKKRVGRSKTAQYGLVEIETVDYAEPVVEKRNDDYVIVYADARLIFFDEYGMPTFTPTAEQLGCPGGEIVWEKSQVRTFQYSPWNFKRQSRDMDRCGIEKGSVFVVSEVKDFSGTSCYVGEFKNEGFGKVIYNPKFLSYDGQGAASYAYEKASEPDAQNSSLSAKRPACDSVLLNYLKHEQRKFNGLSRIYACVNKFVSDESIYWCGEESFASQWGTIRSIASRLNSRTEIMGELFNSEKAYLEHGVAAEKWNENSRKARLKDFLESTAKQEGFSDVEFKSLVVNLAAEMAKKIQGGV
>NC_017448.1|WP_014546243.1|2360221_2361625_+|CRISPR-associated-protein
MESFARSNNVRYLARVVLQAETPVVIGSGDKDSLTDSLVQKDVNGLPYIPASSVAGCLRHAFASKLDVKELERVFGYQKSDDGQGSRVVFTDGRLVGPSGVVDGIQNINFDTDAFFSRFAKLPIRDHVRISHHGAAEKTGKFDEEIVFKGSRFCFEIELVGESNDAQYFDSLLEQMMHSEFRIGAGSRSGFGKVKIVELKKAALDLTNGEDLEKYIGKSSDLSDPTDFWKDLPKERVQDLNTEGWTRYELELTPRDFFLFAAGSGDNDADICAVRASQIEWNDGKPVFTPNLLLIPGSSVKGAISHRVAYRYNKRVGVTLEKLKEAAEAANRDIADLIKENTGCKNKAVQTLFGSQDKDNSCRGRVLLSDVIQKKSSTKILNHVSVDRFTGGAVAGALFSEKVWSKEPSETYTLKFLLEPGEVDADVLGAFEDALKDIAKGMLPLGGGVNRGHGVFEGKVLKNGEVL
>NC_017448.1|WP_014546244.1|2361624_2362017_+|TIGR04423-family-type-III-CRISPR-associated-protein
MNRTINIEQCQGYIWKSDADKPQVFNGCACNLVLDDSANPFVLEAMLYDAQTQDSYMIKYVDGRHLIQEYNLFNKFDDVTEISVLPNRMEGIPELKLKQFWKKTPDKLCNGFETLTPAEIVFAGFKKVGE
>NC_017448.1|WP_014546245.1|2362016_2364284_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MTVKAPFNFVPVSDKVYFPEWASYISHDIPFEDGVSGSIKVKITAKSPIFVRNGHTQGDADEISDAYKQFSNVDGKYYIPGTSIKGAVRSVLEIMSFGKMSTQETHKFAHREWDYKELYQIKGSLLKLRCGWLRRKSDGTYCVQSCGKPWRISFKDLDKYLGKNLFEQNFSNANKKSTDLNTAQKDAQKRGHFEEDPKSAMFKYRFFDDLKKTRDGIHFATIPPKEGKPDKRKVRIDENGEMVGSIVLTGQPDVSGFIDRKQGDGKFYEFVFQDKPEKNYPISEEMFKDLAYIYKDNPEWAYHAKNLETKGIPVFFREEGFGDRAKLVDCGLAYMYKQPFTKSPADWIPSAHNSNNHDLAESIFGYIAKEKDKPSLKGRVQFGHAFSKVTTGCKKDTEFVLANPRASYYPLYASDGSWDDANSIAGRKRYVVRTGEYGVADSVGTDNMKSMANVLNAGAIFEETITFHNLKHIELGALLSALTFHNNATCLHSIGQGKPFGWGATSFEIEELVVEGDREKDCLKYMGEFENAMDDFLGSAWVDDADIKELCAMATPIPTEANSTFEYMKLDNGGVNEFNKQPARCENLDRFTKIASLKKWNNWQMAKPNSIVNMPSDEKEKILADMEMRIQESLAKEAEYAAERAAVEQERREEEQKKAAKKANMDLSFLNTLTTFKDGKNRLEASFKKLDLLPITPDVLDHLSDEARQCIENFVARMFARPEKKWGSKNKDVAKDAAIAEVKKWFGSDYKCQGL
>NC_017448.1|WP_014546246.1|2364288_2364687_+|hypothetical-protein
MPRLFNVTNHSVTDDQRADAIASLGVGDVVDMPPDIARCWGTVPPELDSVCGYVQPVIDWLSSQATKGDVVWVQGEWGAVITVVAWCEARDLRAVYATTKREATEIHGENGVQMTHVFRHVRFRDFPKLGAR

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_017448_9	9.7|2349311|68|NC_017448|CRISPRCasFinder	2349311-2349378	68	NC_017448.1	2346377-2346444	9	0.868
NC_017448_11	11.6|2350953|68|NC_017448|CRISPRCasFinder	2350953-2351020	68	NC_017448.1	2351131-2351198	9	0.868
NC_017448_11	11.6|2350953|68|NC_017448|CRISPRCasFinder	2350953-2351020	68	NC_017448.1	2353348-2353415	9	0.868
NC_017448_9	9.7|2349311|68|NC_017448|CRISPRCasFinder	2349311-2349378	68	NC_017448.1	2343738-2343805	10	0.853
NC_017448_9	9.7|2349311|68|NC_017448|CRISPRCasFinder	2349311-2349378	68	NC_017448.1	2351131-2351198	10	0.853
NC_017448_9	9.7|2349311|68|NC_017448|CRISPRCasFinder	2349311-2349378	68	NC_017448.1	2353348-2353415	10	0.853
NC_017448_9	9.7|2349311|68|NC_017448|CRISPRCasFinder	2349311-2349378	68	NC_017448.1	2353599-2353666	10	0.853
NC_017448_11	11.6|2350953|68|NC_017448|CRISPRCasFinder	2350953-2351020	68	NC_017448.1	2343738-2343805	10	0.853
NC_017448_11	11.6|2350953|68|NC_017448|CRISPRCasFinder	2350953-2351020	68	NC_017448.1	2346377-2346444	10	0.853
NC_017448_12	12.3|2352217|68|NC_017448|CRISPRCasFinder	2352217-2352284	68	NC_017448.1	2342565-2342632	10	0.853

1. spacer 9.7|2349311|68|NC_017448|CRISPRCasFinder matches to position: 2346377-2346444, mismatch: 9, identity: 0.868

ctagcggctgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	CRISPR spacer
ctggcggctgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	Protospacer
**.*********************************************************

2. spacer 11.6|2350953|68|NC_017448|CRISPRCasFinder matches to position: 2351131-2351198, mismatch: 9, identity: 0.868

ctggcggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcactcgc	CRISPR spacer
ctggcggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	Protospacer
******************************************************.*****

3. spacer 11.6|2350953|68|NC_017448|CRISPRCasFinder matches to position: 2353348-2353415, mismatch: 9, identity: 0.868

ctggcggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcactcgc	CRISPR spacer
ctggcggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	Protospacer
******************************************************.*****

4. spacer 9.7|2349311|68|NC_017448|CRISPRCasFinder matches to position: 2343738-2343805, mismatch: 10, identity: 0.853

ctagcggctgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	CRISPR spacer
cttgcggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	Protospacer
** ****.****************************************************

5. spacer 9.7|2349311|68|NC_017448|CRISPRCasFinder matches to position: 2351131-2351198, mismatch: 10, identity: 0.853

ctagcggctgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	CRISPR spacer
ctggcggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	Protospacer
**.****.****************************************************

6. spacer 9.7|2349311|68|NC_017448|CRISPRCasFinder matches to position: 2353348-2353415, mismatch: 10, identity: 0.853

ctagcggctgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	CRISPR spacer
ctggcggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	Protospacer
**.****.****************************************************

7. spacer 9.7|2349311|68|NC_017448|CRISPRCasFinder matches to position: 2353599-2353666, mismatch: 10, identity: 0.853

ctagcggctgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	CRISPR spacer
ctaacggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	Protospacer
***.***.****************************************************

8. spacer 11.6|2350953|68|NC_017448|CRISPRCasFinder matches to position: 2343738-2343805, mismatch: 10, identity: 0.853

ctggcggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcactcgc	CRISPR spacer
cttgcggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	Protospacer
** ***************************************************.*****

9. spacer 11.6|2350953|68|NC_017448|CRISPRCasFinder matches to position: 2346377-2346444, mismatch: 10, identity: 0.853

ctggcggttgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcactcgc	CRISPR spacer
ctggcggctgcctgcttgtcggctcggaaatggtcccgcaagcggtcccgcttcgctcgc	Protospacer
*******.**********************************************.*****

10. spacer 12.3|2352217|68|NC_017448|CRISPRCasFinder matches to position: 2342565-2342632, mismatch: 10, identity: 0.853

ctggcggctgcctgcttgtcggctcggtcatgcccgtgcaagcacggtcgcgacactcgc	CRISPR spacer
ctagcggctgccagcttgtcggctcggtcatgcccgtgcaagcacggtcgcgacactcgc	Protospacer
**.********* ***********************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017448_1	1.31|614592|30|NC_017448|CRISPRCasFinder,PILER-CR	614592-614621	30	MG945149	UNVERIFIED: Microviridae sp. isolate 276-1602, partial genome	4039-4068	2	0.933
NC_017448_1	1.30|614514|30|NC_017448|CRISPRCasFinder,PILER-CR	614514-614543	30	MG945688	UNVERIFIED: Microviridae sp. isolate 1348-1711, complete genome	411-440	5	0.833
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_027630	Propionibacterium phage Ouroboros, complete genome	17238-17267	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR902986	Propionibacterium phage PAC9, complete genome	17328-17357	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	MN813689	Cutibacterium phage P106L, complete genome	17269-17298	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR902984	Propionibacterium phage PAC7, complete genome	17278-17307	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_018842	Propionibacterium phage P1.1, complete genome	17272-17301	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR902982	Propionibacterium phage PAC5, complete genome	17304-17333	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR902979	Propionibacterium phage PAC2, complete genome	17330-17359	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR902987	Propionibacterium phage PAC10, complete genome	17215-17244	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KJ578782	Propionibacterium phage PHL150M00, complete genome	17245-17274	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KJ578792	Propionibacterium phage PHL308M00, complete genome	17246-17275	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_015454	Propionibacterium phage PAD20 endogenous virus, complete genome	17010-17039	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	FJ706171	Propionibacterium phage PAD20, complete genome	17010-17039	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR902985	Propionibacterium phage PAC8, complete genome	17215-17244	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	MN813690	Cutibacterium phage P106M, complete genome	17269-17298	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	MF919533	Propionibacterium phage Supernova, complete genome	17291-17320	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KJ578773	Propionibacterium phage PHL092M00, complete genome	17229-17258	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR902981	Propionibacterium phage PAC4, complete genome	17309-17338	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR337648	Propionibacterium phage SKKY, complete genome	17301-17330	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	MN813692	Cutibacterium phage P106C, complete genome	17269-17298	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	MN813683	Cutibacterium phage P108C, complete genome	17253-17282	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR902978	Propionibacterium phage PAC1, complete genome	17332-17361	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR902980	Propionibacterium phage PAC3, complete genome	17253-17282	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	MN813688	Cutibacterium phage P106I, complete genome	17098-17127	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_027336	Propionibacterium phage PHL009M11, complete genome	17281-17310	6	0.8
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR902983	Propionibacterium phage PAC6, complete genome	17336-17365	6	0.8
NC_017448_1	1.9|612884|30|NC_017448|PILER-CR,CRISPRCasFinder	612884-612913	30	NZ_CP017303	Rhodococcus sp. YL-1 plasmid pYLL1 sequence	277411-277440	6	0.8
NC_017448_1	1.10|612962|29|NC_017448|CRISPRCasFinder	612962-612990	29	KX397369	Erwinia phage vB_EamM_Kwan, complete genome	184343-184371	6	0.793
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP045074	Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence	406222-406251	6	0.8
NC_017448_1	1.14|613272|30|NC_017448|CRISPRCasFinder,PILER-CR	613272-613301	30	KY883654	Vibrio phage JSF10, complete genome	37800-37829	6	0.8
NC_017448_1	1.14|613272|30|NC_017448|CRISPRCasFinder,PILER-CR	613272-613301	30	KP280063	Vibrio phage phi 3, complete genome	58849-58878	6	0.8
NC_017448_1	1.14|613272|30|NC_017448|CRISPRCasFinder,PILER-CR	613272-613301	30	NC_047882	Vibrio phage JSF12, complete genome	107710-107739	6	0.8
NC_017448_1	1.16|613428|30|NC_017448|CRISPRCasFinder,PILER-CR	613428-613457	30	NZ_AP019717	Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence	349932-349961	6	0.8
NC_017448_1	1.19|613661|30|NC_017448|CRISPRCasFinder,PILER-CR	613661-613690	30	AP013460	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-U-MedDCM-OCT-S40-C18	24442-24471	6	0.8
NC_017448_1	1.21|613816|30|NC_017448|CRISPRCasFinder,PILER-CR	613816-613845	30	AP013460	Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-U-MedDCM-OCT-S40-C18	24442-24471	6	0.8
NC_017448_1	1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder	612262-612290	29	NC_015462	Candidatus Rickettsia amblyommii AaR/SC plasmid pRAM32, complete sequence	1095-1123	7	0.759
NC_017448_1	1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder	612262-612290	29	NC_007207	Leuconostoc mesenteroides plasmid pFMBL1, complete sequence	3946-3974	7	0.759
NC_017448_1	1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder	612262-612290	29	NZ_CP015013	Rickettsia amblyommatis isolate An13 plasmid unnamed_2, complete sequence	3213-3241	7	0.759
NC_017448_1	1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder	612262-612290	29	NZ_CP012010	Leuconostoc mesenteroides subsp. dextranicum strain DSM 20484 plasmid pDSM20484, complete sequence	16904-16932	7	0.759
NC_017448_1	1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder	612262-612290	29	NZ_CP012010	Leuconostoc mesenteroides subsp. dextranicum strain DSM 20484 plasmid pDSM20484, complete sequence	33806-33834	7	0.759
NC_017448_1	1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder	612262-612290	29	NC_010467	Leuconostoc citreum KM20 plasmid pLCK3, complete sequence	4268-4296	7	0.759
NC_017448_1	1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder	612262-612290	29	NC_017020	Rickettsia amblyommatis str. GAT-30V plasmid pMCE_1, complete sequence	17918-17946	7	0.759
NC_017448_1	1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder	612262-612290	29	MN693002	Marine virus AFVG_117M54, complete genome	7531-7559	7	0.759
NC_017448_1	1.7|612728|30|NC_017448|PILER-CR,CRISPRCasFinder	612728-612757	30	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	278406-278435	7	0.767
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_027333	Propionibacterium phage PHL070N00, complete genome	17224-17253	7	0.767
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NZ_CP015356	Bacillus thuringiensis strain MYBT18246 plasmid p101287, complete sequence	87293-87322	7	0.767
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	FJ706172	Propionibacterium phage PAS50, complete genome	17179-17208	7	0.767
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_022337	Propionibacterium phage PHL071N05, complete genome	17250-17279	7	0.767
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_015453	Propionibacterium phage PAS50 endogenous virus, complete genome	17179-17208	7	0.767
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_028694	Propionibacterium phage PA1-14, complete genome	17231-17260	7	0.767
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	JX262218	Propionibacterium phage P104A, complete genome	17032-17061	7	0.767
NC_017448_1	1.9|612884|30|NC_017448|PILER-CR,CRISPRCasFinder	612884-612913	30	NZ_CP011296	Rhodococcus erythropolis strain BG43 plasmid pRLCBG43, complete sequence	186672-186701	7	0.767
NC_017448_1	1.9|612884|30|NC_017448|PILER-CR,CRISPRCasFinder	612884-612913	30	NC_008826	Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence	187803-187832	7	0.767
NC_017448_1	1.9|612884|30|NC_017448|PILER-CR,CRISPRCasFinder	612884-612913	30	NC_016650	Rhodococcus phage RGL3, complete genome	33018-33047	7	0.767
NC_017448_1	1.10|612962|29|NC_017448|CRISPRCasFinder	612962-612990	29	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	29502-29530	7	0.759
NC_017448_1	1.15|613350|30|NC_017448|CRISPRCasFinder,PILER-CR	613350-613379	30	NZ_CP010837	Sphingomonas hengshuiensis strain WHSC-8 isolate soil of Hengshui Lake plasmid unnamed, complete sequence	36383-36412	7	0.767
NC_017448_1	1.18|613584|29|NC_017448|CRISPRCasFinder,PILER-CR	613584-613612	29	MK415401	Phage apr34_1789, complete genome	3721-3749	7	0.759
NC_017448_1	1.18|613584|29|NC_017448|CRISPRCasFinder,PILER-CR	613584-613612	29	MK415401	Phage apr34_1789, complete genome	30968-30996	7	0.759
NC_017448_1	1.18|613584|29|NC_017448|CRISPRCasFinder,PILER-CR	613584-613612	29	MK415401	Phage apr34_1789, complete genome	58094-58122	7	0.759
NC_017448_1	1.29|614437|29|NC_017448|CRISPRCasFinder,PILER-CR	614437-614465	29	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	319451-319479	7	0.759
NC_017448_1	1.29|614437|29|NC_017448|CRISPRCasFinder,PILER-CR	614437-614465	29	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	83726-83754	7	0.759
NC_017448_4	4.2|2343601|29|NC_017448|PILER-CR	2343601-2343629	29	MW149089	Microvirus sp. isolate gila9, complete genome	3368-3396	7	0.759
NC_017448_1	1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder	612262-612290	29	KJ608189	UNVERIFIED: Leuconostoc phage LLC-1, partial genome	13745-13773	8	0.724
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	MG820634	Propionibacterium phage pa27, complete genome	17225-17254	8	0.733
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	JX570711	Propionibacterium phage PHL066M04, complete genome	17245-17274	8	0.733
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	JX262220	Propionibacterium phage P100D, complete genome	17226-17255	8	0.733
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_041957	Propionibacterium phage PHL151N00, complete genome	17245-17274	8	0.733
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KJ578787	Propionibacterium phage PHL171M01, complete genome	17254-17283	8	0.733
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	JX570703	Propionibacterium phage PHL073M02, complete genome	17236-17265	8	0.733
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_027627	Propionibacterium phage Solid, complete genome	17228-17257	8	0.733
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_022336	Propionibacterium phage PHL010M04, complete genome	17245-17274	8	0.733
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_027347	Propionibacterium phage PHL151M00, complete genome	17245-17274	8	0.733
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	NC_022342	Propionibacterium phage PHL111M01, complete genome	17234-17263	8	0.733
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	KR347353	Propionibacterium phage Enoki, complete genome	17243-17272	8	0.733
NC_017448_1	1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR	613194-613223	30	NZ_CP050104	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence	343983-344012	8	0.733
NC_017448_1	1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR	613194-613223	30	NZ_CP025507	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence	46758-46787	8	0.733
NC_017448_1	1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR	613194-613223	30	NZ_CP050109	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence	343983-344012	8	0.733
NC_017448_1	1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR	613194-613223	30	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	760878-760907	8	0.733
NC_017448_1	1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR	613194-613223	30	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	358008-358037	8	0.733
NC_017448_1	1.16|613428|30|NC_017448|CRISPRCasFinder,PILER-CR	613428-613457	30	MG018926	Pseudomonas phage tabernarius, complete genome	19373-19402	8	0.733
NC_017448_1	1.18|613584|29|NC_017448|CRISPRCasFinder,PILER-CR	613584-613612	29	NZ_DQ996271	Burkholderia glumae BGR1 plasmid pBGF3, complete sequence	23563-23591	8	0.724
NC_017448_1	1.29|614437|29|NC_017448|CRISPRCasFinder,PILER-CR	614437-614465	29	NZ_CP025513	Neorhizobium sp. SOG26 plasmid unnamed2, complete sequence	58799-58827	8	0.724
NC_017448_1	1.31|614592|30|NC_017448|CRISPRCasFinder,PILER-CR	614592-614621	30	NC_013085	Synechococcus phage S-RSM4, complete genome	95498-95527	8	0.733
NC_017448_1	1.31|614592|30|NC_017448|CRISPRCasFinder,PILER-CR	614592-614621	30	FM207411	Synechococcus phage S-RSM4 complete genome	95498-95527	8	0.733
NC_017448_3	3.1|2342011|42|NC_017448|CRISPRCasFinder	2342011-2342052	42	NZ_CP045273	Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence	454923-454964	8	0.81
NC_017448_3	3.8|2342017|36|NC_017448|CRT	2342017-2342052	36	NZ_CP045273	Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence	454929-454964	8	0.778
NC_017448_4	4.1|2343523|32|NC_017448|PILER-CR	2343523-2343554	32	NZ_CP007510	Pseudomonas stutzeri strain 19SMN4 plasmid pLIB119, complete plasmid	99481-99512	8	0.75
NC_017448_4	4.1|2343523|32|NC_017448|PILER-CR	2343523-2343554	32	NZ_CP046903	Pseudomonas stutzeri strain PM101005 plasmid p1_PM101005, complete sequence	54699-54730	8	0.75
NC_017448_4	4.2|2343601|29|NC_017448|PILER-CR	2343601-2343629	29	MH616963	CrAssphage sp. isolate ctbg_1, complete genome	87964-87992	8	0.724
NC_017448_1	1.2|612339|30|NC_017448|PILER-CR,CRISPRCasFinder	612339-612368	30	NZ_CP011157	Bacillus cereus strain HN001 plasmid pRML02, complete sequence	21033-21062	9	0.7
NC_017448_1	1.7|612728|30|NC_017448|PILER-CR,CRISPRCasFinder	612728-612757	30	NZ_CP022417	Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-2, complete sequence	74858-74887	9	0.7
NC_017448_1	1.7|612728|30|NC_017448|PILER-CR,CRISPRCasFinder	612728-612757	30	NZ_CP054600	Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed1, complete sequence	26882-26911	9	0.7
NC_017448_1	1.7|612728|30|NC_017448|PILER-CR,CRISPRCasFinder	612728-612757	30	MH884513	Bacillus phage vB_BpsS-36, complete genome	2905-2934	9	0.7
NC_017448_1	1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder	612806-612835	30	MN693712	Marine virus AFVG_250M462, complete genome	34328-34357	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP020900	Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5d, complete sequence	409312-409341	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013526	Rhizobium phaseoli strain R744 plasmid pRphaR744d, complete sequence	46750-46779	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013556	Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence	46750-46779	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP020910	Rhizobium etli strain NXC12 plasmid pRetNXC12d, complete sequence	94754-94783	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013589	Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence	46329-46358	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013562	Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence	46748-46777	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013579	Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence	49631-49660	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013531	Rhizobium phaseoli strain R723 plasmid pRphaR723d, complete sequence	47939-47968	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013536	Rhizobium phaseoli strain R650 plasmid pRphaR650d, complete sequence	46754-46783	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013541	Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence	46509-46538	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013546	Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence	49622-49651	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013567	Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence	46750-46779	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013584	Rhizobium phaseoli strain N261 plasmid pRphaN261d, complete sequence	47939-47968	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP048424	Rhizobium daejeonense strain KACC 13094 plasmid unnamed1, complete sequence	220099-220128	9	0.7
NC_017448_1	1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR	613039-613068	30	NZ_CP013573	Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence	49631-49660	9	0.7
NC_017448_1	1.25|614126|30|NC_017448|CRISPRCasFinder,PILER-CR	614126-614155	30	GU071094	Synechococcus phage S-SM1, complete genome	44985-45014	9	0.7
NC_017448_1	1.31|614592|30|NC_017448|CRISPRCasFinder,PILER-CR	614592-614621	30	NZ_CP022563	Pseudomonas monteilii strain B5 plasmid pSH5-1, complete sequence	52976-53005	9	0.7

1. spacer 1.31|614592|30|NC_017448|CRISPRCasFinder,PILER-CR matches to MG945149 (UNVERIFIED: Microviridae sp. isolate 276-1602, partial genome) position: , mismatch: 2, identity: 0.933

tgcttgacgaagttggcaatgaatggtaca	CRISPR spacer
tgcttgacgaagttggtaatgaatggtata	Protospacer
****************.***********.*

2. spacer 1.30|614514|30|NC_017448|CRISPRCasFinder,PILER-CR matches to MG945688 (UNVERIFIED: Microviridae sp. isolate 1348-1711, complete genome) position: , mismatch: 5, identity: 0.833

aatctgtaagcactattggaaatatggtct	CRISPR spacer
actttttaagcattattggaaaaatggtct	Protospacer
* *.* ******.********* *******

3. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_027630 (Propionibacterium phage Ouroboros, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatccc	Protospacer
* *.  ****** ****************.

4. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR902986 (Propionibacterium phage PAC9, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

5. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to MN813689 (Cutibacterium phage P106L, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

6. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR902984 (Propionibacterium phage PAC7, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

7. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_018842 (Propionibacterium phage P1.1, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

8. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR902982 (Propionibacterium phage PAC5, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

9. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR902979 (Propionibacterium phage PAC2, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

10. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR902987 (Propionibacterium phage PAC10, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

11. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KJ578782 (Propionibacterium phage PHL150M00, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

12. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KJ578792 (Propionibacterium phage PHL308M00, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

13. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_015454 (Propionibacterium phage PAD20 endogenous virus, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

14. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to FJ706171 (Propionibacterium phage PAD20, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

15. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR902985 (Propionibacterium phage PAC8, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

16. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to MN813690 (Cutibacterium phage P106M, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

17. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to MF919533 (Propionibacterium phage Supernova, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

18. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KJ578773 (Propionibacterium phage PHL092M00, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

19. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR902981 (Propionibacterium phage PAC4, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

20. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR337648 (Propionibacterium phage SKKY, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

21. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to MN813692 (Cutibacterium phage P106C, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

22. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to MN813683 (Cutibacterium phage P108C, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

23. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR902978 (Propionibacterium phage PAC1, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

24. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR902980 (Propionibacterium phage PAC3, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

25. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to MN813688 (Cutibacterium phage P106I, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

26. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_027336 (Propionibacterium phage PHL009M11, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tgttgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

27. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR902983 (Propionibacterium phage PAC6, complete genome) position: , mismatch: 6, identity: 0.8

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattgtgtgtgttgttcatggttttatccc	Protospacer
* *. * ***** ****************.

28. spacer 1.9|612884|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NZ_CP017303 (Rhodococcus sp. YL-1 plasmid pYLL1 sequence) position: , mismatch: 6, identity: 0.8

aggtctgctggtcttccgggaag-agcatct	CRISPR spacer
gcgtctgcttgtcttccgggaagccgcata-	Protospacer
. ******* *************  ****  

29. spacer 1.10|612962|29|NC_017448|CRISPRCasFinder matches to KX397369 (Erwinia phage vB_EamM_Kwan, complete genome) position: , mismatch: 6, identity: 0.793

ggaacgcgcaccgtttgacgcaaagaaag	CRISPR spacer
tgatggcgcaccgtttaaggcaaagaaat	Protospacer
 **  ***********.* ********* 

30. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP045074 (Paracoccus kondratievae strain BJQ0001 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
gatgctcggcatctggccgaaccgcggcgg	Protospacer
************** ******  ** * .*

31. spacer 1.14|613272|30|NC_017448|CRISPRCasFinder,PILER-CR matches to KY883654 (Vibrio phage JSF10, complete genome) position: , mismatch: 6, identity: 0.8

gcaagtatggtaatatgtatgaccacggcg	CRISPR spacer
gcctatatggtactatgtatgactacggag	Protospacer
**  .******* **********.**** *

32. spacer 1.14|613272|30|NC_017448|CRISPRCasFinder,PILER-CR matches to KP280063 (Vibrio phage phi 3, complete genome) position: , mismatch: 6, identity: 0.8

gcaagtatggtaatatgtatgaccacggcg	CRISPR spacer
gcctatatggtactatgtatgactacggag	Protospacer
**  .******* **********.**** *

33. spacer 1.14|613272|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NC_047882 (Vibrio phage JSF12, complete genome) position: , mismatch: 6, identity: 0.8

gcaagtatggtaatatgtatgaccacggcg	CRISPR spacer
gcctatatggtactatgtatgactacggag	Protospacer
**  .******* **********.**** *

34. spacer 1.16|613428|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_AP019717 (Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence) position: , mismatch: 6, identity: 0.8

-tacaaagataggatgttgcatatttattaa	CRISPR spacer
ctattgaaa-aggatgttgcatatttcttaa	Protospacer
 **. .*.* **************** ****

35. spacer 1.19|613661|30|NC_017448|CRISPRCasFinder,PILER-CR matches to AP013460 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-U-MedDCM-OCT-S40-C18) position: , mismatch: 6, identity: 0.8

gctactgtgcagtcattacaagaccgcgtt	CRISPR spacer
tctattgtgcagtcattacaagagcaattt	Protospacer
 ***.****************** *.  **

36. spacer 1.21|613816|30|NC_017448|CRISPRCasFinder,PILER-CR matches to AP013460 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G17, isolate: uvMED-CGR-U-MedDCM-OCT-S40-C18) position: , mismatch: 6, identity: 0.8

gctactgtgcagtcattacaagaccgcgtt	CRISPR spacer
tctattgtgcagtcattacaagagcaattt	Protospacer
 ***.****************** *.  **

37. spacer 1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_015462 (Candidatus Rickettsia amblyommii AaR/SC plasmid pRAM32, complete sequence) position: , mismatch: 7, identity: 0.759

gcatatctgaataaactaaacaacaaaaa	CRISPR spacer
ccatatctgaataaactaaataaaatttt	Protospacer
 *******************.** *    

38. spacer 1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_007207 (Leuconostoc mesenteroides plasmid pFMBL1, complete sequence) position: , mismatch: 7, identity: 0.759

gcatatctgaataaactaaacaacaaaaa	CRISPR spacer
aattatctgaacaaactgaacaacaaatt	Protospacer
.  ********.*****.*********  

39. spacer 1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder matches to NZ_CP015013 (Rickettsia amblyommatis isolate An13 plasmid unnamed_2, complete sequence) position: , mismatch: 7, identity: 0.759

gcatatctgaataaactaaacaacaaaaa	CRISPR spacer
ccatatctgaataaactaaataaaatttt	Protospacer
 *******************.** *    

40. spacer 1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder matches to NZ_CP012010 (Leuconostoc mesenteroides subsp. dextranicum strain DSM 20484 plasmid pDSM20484, complete sequence) position: , mismatch: 7, identity: 0.759

gcatatctgaataaactaaacaacaaaaa	CRISPR spacer
aattatctgaacaaactgaacaacaaatt	Protospacer
.  ********.*****.*********  

41. spacer 1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder matches to NZ_CP012010 (Leuconostoc mesenteroides subsp. dextranicum strain DSM 20484 plasmid pDSM20484, complete sequence) position: , mismatch: 7, identity: 0.759

gcatatctgaataaactaaacaacaaaaa	CRISPR spacer
aattatctgaacaaactgaacaacaaatt	Protospacer
.  ********.*****.*********  

42. spacer 1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_010467 (Leuconostoc citreum KM20 plasmid pLCK3, complete sequence) position: , mismatch: 7, identity: 0.759

gcatatctgaataaactaaacaacaaaaa	CRISPR spacer
aattatctgaacaaactgaacaacaaatt	Protospacer
.  ********.*****.*********  

43. spacer 1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_017020 (Rickettsia amblyommatis str. GAT-30V plasmid pMCE_1, complete sequence) position: , mismatch: 7, identity: 0.759

gcatatctgaataaactaaacaacaaaaa	CRISPR spacer
ccatatctgaataaactaaataaaatttt	Protospacer
 *******************.** *    

44. spacer 1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder matches to MN693002 (Marine virus AFVG_117M54, complete genome) position: , mismatch: 7, identity: 0.759

gcatatctgaataaactaaacaacaaaaa	CRISPR spacer
gcatatctgaaaaaactaatcaattctat	Protospacer
*********** ******* ***.   * 

45. spacer 1.7|612728|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 7, identity: 0.767

tagatatttttgacaatttggattgtatct	CRISPR spacer
aaaggatttttgtaaatttggattgtatcg	Protospacer
 *.. *******  *************** 

46. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_027333 (Propionibacterium phage PHL070N00, complete genome) position: , mismatch: 7, identity: 0.767

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tatggtttgtgttgttcatggttttatttc	Protospacer
* *  ******* **************...

47. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NZ_CP015356 (Bacillus thuringiensis strain MYBT18246 plasmid p101287, complete sequence) position: , mismatch: 7, identity: 0.767

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
actcttttttgtagttcatgtttttgtttt	Protospacer
 .****** *********** ****.*..*

48. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to FJ706172 (Propionibacterium phage PAS50, complete genome) position: , mismatch: 7, identity: 0.767

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttatgttgttcatggttttatccc	Protospacer
* *.  **.*** ****************.

49. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_022337 (Propionibacterium phage PHL071N05, complete genome) position: , mismatch: 7, identity: 0.767

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttatgttgttcatggttttatccc	Protospacer
* *.  **.*** ****************.

50. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_015453 (Propionibacterium phage PAS50 endogenous virus, complete genome) position: , mismatch: 7, identity: 0.767

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttatgttgttcatggttttatccc	Protospacer
* *.  **.*** ****************.

51. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_028694 (Propionibacterium phage PA1-14, complete genome) position: , mismatch: 7, identity: 0.767

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgtccatggttttatccc	Protospacer
* *.  ****** **.*************.

52. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to JX262218 (Propionibacterium phage P104A, complete genome) position: , mismatch: 7, identity: 0.767

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgtccatggttttatccc	Protospacer
* *.  ****** **.*************.

53. spacer 1.9|612884|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NZ_CP011296 (Rhodococcus erythropolis strain BG43 plasmid pRLCBG43, complete sequence) position: , mismatch: 7, identity: 0.767

aggtctgctggtcttccgggaagagcatct-	CRISPR spacer
gcgtctgcttgtcttccgggaag-ccacata	Protospacer
. ******* *************  **. * 

54. spacer 1.9|612884|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_008826 (Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence) position: , mismatch: 7, identity: 0.767

aggtctgctggtcttccgggaagagcatct	CRISPR spacer
gggtcagctggtcttccgggaggatcgaca	Protospacer
.**** ***************.** *. * 

55. spacer 1.9|612884|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_016650 (Rhodococcus phage RGL3, complete genome) position: , mismatch: 7, identity: 0.767

aggtctgctggtcttccgggaagagcatct	CRISPR spacer
tcctctgccggacttccgggaagagcctgt	Protospacer
   *****.** ************** * *

56. spacer 1.10|612962|29|NC_017448|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 7, identity: 0.759

ggaacgcgcaccgtttgacgcaaagaaag	CRISPR spacer
ggaacgcgcgccgtttgacgaaatcgtcg	Protospacer
*********.********** **  .  *

57. spacer 1.15|613350|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP010837 (Sphingomonas hengshuiensis strain WHSC-8 isolate soil of Hengshui Lake plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

agtattcggactatatcgggcgggctcgtt	CRISPR spacer
atgggccggactatatttggcgggctcgtt	Protospacer
*  . .**********. ************

58. spacer 1.18|613584|29|NC_017448|CRISPRCasFinder,PILER-CR matches to MK415401 (Phage apr34_1789, complete genome) position: , mismatch: 7, identity: 0.759

agaagagcgagttcacgccgttgtgggtt	CRISPR spacer
acgagaacgagttcacgccgttgttgaag	Protospacer
* .***.***************** *.  

59. spacer 1.18|613584|29|NC_017448|CRISPRCasFinder,PILER-CR matches to MK415401 (Phage apr34_1789, complete genome) position: , mismatch: 7, identity: 0.759

agaagagcgagttcacgccgttgtgggtt	CRISPR spacer
acgagaacgagttcacgccgttgttgaag	Protospacer
* .***.***************** *.  

60. spacer 1.18|613584|29|NC_017448|CRISPRCasFinder,PILER-CR matches to MK415401 (Phage apr34_1789, complete genome) position: , mismatch: 7, identity: 0.759

agaagagcgagttcacgccgttgtgggtt	CRISPR spacer
acgagaacgagttcacgccgttgttgaag	Protospacer
* .***.***************** *.  

61. spacer 1.29|614437|29|NC_017448|CRISPRCasFinder,PILER-CR matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 7, identity: 0.759

tatcgacttgcgacaacgaagctcttgat	CRISPR spacer
cggccacttgcgtcaaccaagctcttgag	Protospacer
.. * ******* **** ********** 

62. spacer 1.29|614437|29|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.759

tatcgacttgcgacaacgaagctcttgat	CRISPR spacer
cgcccacttgcgtcaaccaagctcttgag	Protospacer
...* ******* **** ********** 

63. spacer 4.2|2343601|29|NC_017448|PILER-CR matches to MW149089 (Microvirus sp. isolate gila9, complete genome) position: , mismatch: 7, identity: 0.759

ttattatagataatgaagttcttaggttc	CRISPR spacer
ctattatagacaatgaaggtcttattctt	Protospacer
.*********.******* *****  .*.

64. spacer 1.1|612262|29|NC_017448|PILER-CR,CRISPRCasFinder matches to KJ608189 (UNVERIFIED: Leuconostoc phage LLC-1, partial genome) position: , mismatch: 8, identity: 0.724

gcatatctgaataaactaaacaacaaaaa	CRISPR spacer
ctataactgaataaactaaaaaacacccg	Protospacer
 .*** ************** ****   .

65. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to MG820634 (Propionibacterium phage pa27, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

66. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to JX570711 (Propionibacterium phage PHL066M04, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

67. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to JX262220 (Propionibacterium phage P100D, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

68. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_041957 (Propionibacterium phage PHL151N00, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

69. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KJ578787 (Propionibacterium phage PHL171M01, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

70. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to JX570703 (Propionibacterium phage PHL073M02, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

71. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_027627 (Propionibacterium phage Solid, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

72. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_022336 (Propionibacterium phage PHL010M04, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

73. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_027347 (Propionibacterium phage PHL151M00, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

74. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NC_022342 (Propionibacterium phage PHL111M01, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

75. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to KR347353 (Propionibacterium phage Enoki, complete genome) position: , mismatch: 8, identity: 0.733

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
tattggttgtgttgttcatggttttatttc	Protospacer
* *.  ****** **************...

76. spacer 1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP050104 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b2, complete sequence) position: , mismatch: 8, identity: 0.733

gctggccctcttggtgctatggccgcaggc	CRISPR spacer
gaccttcacctcggtgctatggccgcaggc	Protospacer
* .  .* .**.******************

77. spacer 1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP025507 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvA, complete sequence) position: , mismatch: 8, identity: 0.733

gctggccctcttggtgctatggccgcaggc	CRISPR spacer
gaccttcacctcggtgctatggccgcaggc	Protospacer
* .  .* .**.******************

78. spacer 1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP050109 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b2, complete sequence) position: , mismatch: 8, identity: 0.733

gctggccctcttggtgctatggccgcaggc	CRISPR spacer
gaccttcacctcggtgctatggccgcaggc	Protospacer
* .  .* .**.******************

79. spacer 1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 8, identity: 0.733

gctggccctcttggtgctatggccgcaggc	CRISPR spacer
gaccttcacctcggtgctatggccgcaggc	Protospacer
* .  .* .**.******************

80. spacer 1.13|613194|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 8, identity: 0.733

gctggccctcttggtgctatggccgcaggc	CRISPR spacer
gaccttcacctcggtgctatggccgcaggc	Protospacer
* .  .* .**.******************

81. spacer 1.16|613428|30|NC_017448|CRISPRCasFinder,PILER-CR matches to MG018926 (Pseudomonas phage tabernarius, complete genome) position: , mismatch: 8, identity: 0.733

tacaaagataggatgttgcatatttattaa	CRISPR spacer
cgacaagttaggaagttgcatatttatttc	Protospacer
..  *** ***** **************  

82. spacer 1.18|613584|29|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_DQ996271 (Burkholderia glumae BGR1 plasmid pBGF3, complete sequence) position: , mismatch: 8, identity: 0.724

agaagagcgagttcacgccgttgtgggtt	CRISPR spacer
gccagagcgagttcacgccgtcgtagcgg	Protospacer
.  ******************.**.*   

83. spacer 1.29|614437|29|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP025513 (Neorhizobium sp. SOG26 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.724

tatcgacttgcgacaacgaagctcttgat	CRISPR spacer
cagggacttgcgacaacgaagcgctccga	Protospacer
.*  ****************** **. . 

84. spacer 1.31|614592|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NC_013085 (Synechococcus phage S-RSM4, complete genome) position: , mismatch: 8, identity: 0.733

tgcttgacgaagttggcaatgaatggtaca	CRISPR spacer
tgctagacgaagatggcaatgaagtagaag	Protospacer
**** ******* **********  . * .

85. spacer 1.31|614592|30|NC_017448|CRISPRCasFinder,PILER-CR matches to FM207411 (Synechococcus phage S-RSM4 complete genome) position: , mismatch: 8, identity: 0.733

tgcttgacgaagttggcaatgaatggtaca	CRISPR spacer
tgctagacgaagatggcaatgaagtagaag	Protospacer
**** ******* **********  . * .

86. spacer 3.1|2342011|42|NC_017448|CRISPRCasFinder matches to NZ_CP045273 (Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence) position: , mismatch: 8, identity: 0.81

--taagacttaaactcttttgttgctttgaagggattaaaatag	CRISPR spacer
gaacagactt--actcttttgttgctttgaagtaattaaaatgt	Protospacer
    ******  ******************** .********. 

87. spacer 3.8|2342017|36|NC_017448|CRT matches to NZ_CP045273 (Bacillus megaterium strain FDU301 plasmid pFDU301A, complete sequence) position: , mismatch: 8, identity: 0.778

ttaaactcttttgttgctttgaagggattaaaatag	CRISPR spacer
acttactcttttgttgctttgaagtaattaaaatgt	Protospacer
 .  ******************** .********. 

88. spacer 4.1|2343523|32|NC_017448|PILER-CR matches to NZ_CP007510 (Pseudomonas stutzeri strain 19SMN4 plasmid pLIB119, complete plasmid) position: , mismatch: 8, identity: 0.75

ttgcttcgcagcgttgcttatggaagagcgta	CRISPR spacer
ttgcttcgcagctttgcatatggctttgggtc	Protospacer
************ **** *****    * ** 

89. spacer 4.1|2343523|32|NC_017448|PILER-CR matches to NZ_CP046903 (Pseudomonas stutzeri strain PM101005 plasmid p1_PM101005, complete sequence) position: , mismatch: 8, identity: 0.75

ttgcttcgcagcgttgcttatggaagagcgta	CRISPR spacer
ttgcttcgcagctttgcatatggctttgggtc	Protospacer
************ **** *****    * ** 

90. spacer 4.2|2343601|29|NC_017448|PILER-CR matches to MH616963 (CrAssphage sp. isolate ctbg_1, complete genome) position: , mismatch: 8, identity: 0.724

ttattatagataatgaagttcttaggttc	CRISPR spacer
ttattataggtaatgtagttcttgataat	Protospacer
*********.***** *******..   .

91. spacer 1.2|612339|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NZ_CP011157 (Bacillus cereus strain HN001 plasmid pRML02, complete sequence) position: , mismatch: 9, identity: 0.7

tattttcagtgtaggtcatgatttacccca	CRISPR spacer
tattttcagtataggtcattattactttgg	Protospacer
**********.******** ***  ... .

92. spacer 1.7|612728|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NZ_CP022417 (Sulfitobacter pseudonitzschiae strain SMR1 plasmid pSMR1-2, complete sequence) position: , mismatch: 9, identity: 0.7

tagatatttttgacaatttggattgtatct	CRISPR spacer
gccctatttttgccaagttggattgtaata	Protospacer
    ******** *** ********** . 

93. spacer 1.7|612728|30|NC_017448|PILER-CR,CRISPRCasFinder matches to NZ_CP054600 (Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

tagatatttttgacaatttggattgtatct	CRISPR spacer
gccctatttttgccaatttggactgtaata	Protospacer
    ******** *********.**** . 

94. spacer 1.7|612728|30|NC_017448|PILER-CR,CRISPRCasFinder matches to MH884513 (Bacillus phage vB_BpsS-36, complete genome) position: , mismatch: 9, identity: 0.7

tagatatttttgacaatttggattgtatct	CRISPR spacer
aggatatttttgacaatatggatgacttac	Protospacer
 .*************** ***** .. * .

95. spacer 1.8|612806|30|NC_017448|PILER-CR,CRISPRCasFinder matches to MN693712 (Marine virus AFVG_250M462, complete genome) position: , mismatch: 9, identity: 0.7

tttcttttgtgtagttcatggttttatcct	CRISPR spacer
accacattgtgtagtacatggttttatttt	Protospacer
 .. . ********* ***********..*

96. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP020900 (Rhizobium phaseoli Brasil 5 strain Bra5 plasmid pRphaBra5d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

97. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013526 (Rhizobium phaseoli strain R744 plasmid pRphaR744d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

98. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013556 (Rhizobium phaseoli strain N931 plasmid pRphaN931d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

99. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP020910 (Rhizobium etli strain NXC12 plasmid pRetNXC12d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
gcctaccggcatcttgccgaatggccggcc	Protospacer
* .  .*************** *****.  

100. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013589 (Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

101. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013562 (Rhizobium phaseoli strain N841 plasmid pRphaN841e, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

102. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013579 (Rhizobium phaseoli strain N671 plasmid pRphaN671e, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

103. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013531 (Rhizobium phaseoli strain R723 plasmid pRphaR723d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

104. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013536 (Rhizobium phaseoli strain R650 plasmid pRphaR650d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

105. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013541 (Rhizobium phaseoli strain R630 plasmid pRphaR630d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

106. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013546 (Rhizobium phaseoli strain R620 plasmid pRphaR620d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

107. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013567 (Rhizobium phaseoli strain N831 plasmid pRphaN831d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

108. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013584 (Rhizobium phaseoli strain N261 plasmid pRphaN261d, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

109. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP048424 (Rhizobium daejeonense strain KACC 13094 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
gcctaccggcatcttgccgaatggccggca	Protospacer
* .  .*************** *****. .

110. spacer 1.11|613039|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP013573 (Rhizobium phaseoli strain N771 plasmid pRphaN771e, complete sequence) position: , mismatch: 9, identity: 0.7

gatgctcggcatcttgccgaaaggccgaag	CRISPR spacer
cttgctcggcctcttgccgaaagcggaata	Protospacer
  ******** ************   .* .

111. spacer 1.25|614126|30|NC_017448|CRISPRCasFinder,PILER-CR matches to GU071094 (Synechococcus phage S-SM1, complete genome) position: , mismatch: 9, identity: 0.7

gggtggaggctttaatgtccttagatgttc	CRISPR spacer
tattttgtgctttaatgcccttagatgttg	Protospacer
 . *  . *********.*********** 

112. spacer 1.31|614592|30|NC_017448|CRISPRCasFinder,PILER-CR matches to NZ_CP022563 (Pseudomonas monteilii strain B5 plasmid pSH5-1, complete sequence) position: , mismatch: 9, identity: 0.7

tgcttgacgaagttggcaatgaatggtaca	CRISPR spacer
tgattgacgaagttggcaatgcgtttcttg	Protospacer
** ****************** .*  . ..