CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_006368	Legionella pneumophila str. Paris, complete genome	3 crisprs	cas1,cas2,cas4,cas3,DEDDh,DinG,WYL,csa3	0	7	7	0
NC_006365	Legionella pneumophila str. Paris plasmid pLPP, complete sequence	0 crisprs	PD-DExK,WYL	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_006368_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006368_1

190034-192439

TypeII

Consensus_repeat	Method
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CRISPRCasFinder
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CRT

33 spacers

cas4,cas2,cas1,cas9

The CRISPR arrays of NC_006368_1

>merge|NC_006368|1|190034-192439|CRISPRCasFinder,CRT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTAGATATAAAAAGATTAAATCTTCTAGCGCACATCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTCACTACTCCTGAAGGTTATAATTTTTGCTATAACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTTCGAATACAATCCTAGTGTCTCTGTGTGAATTAAGCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCAGGCACTGGTTCACTAGACACTGTAACATCTATCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCAATAACAAGCGAGCCTTTTGTACTAGAAGGTTTACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCTACCAGTTAATCGTAACTCAATCTCTTTTTCAACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACATAGAATACATAAGTGCAAATTATTAAATGTTACCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTGAATGTAGAAACCAGATGCCACGAATTATTAGACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTTTGTATAAACGTTCTGATATGACTTAGGTAATCTCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCTAACCTGATTGCTCAACAAATAATGCTATTGGCCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTCACTTTAGGCCAACGCCGATCCTCCGCTTCGAACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTGACGCAAAGGATTTATTAAAAACGCCTTGTAATCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACATTTTACCTTTTAACACATATTGATAGGCGTCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTCCATAACTGAAACGTCCTTATGCCTCAACATAATGCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACGAATTTGTCGGCCGCATAGACCGCTTTTATCAAACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCTATTGCAAGCTAGTTTGATCGTGTTATTATAAGAACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTGACAAACGTTTGTTTTTTAGACACAACACTAAAAGCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCCTGAAAACCCGCCACAACCCGCGCCAGACTTGAACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACACCAAGTCGAAACAACATACCGAGACCGTGTTGACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTACATTGTTACGTTCATTTCACTCAGTTTTTCATACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACAGCAATAACCCAAAGTTTCGCGCGCGTGCGCGGGCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTTATAACATCGGGATGGCGGTTTATTGGTTAAGTAACCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTTCTTTTTTCAGATTTCATTTCCTTTTCCTTGTGCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACAATCTTAATTTATGCGCCTTACCTTCTGCTTCATCCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTATACTTAGACAATATCATCATTTCCTATGTTTCGACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACGCTATTCCAGATAGGTAGTTGTTTAGAGCATTTTGTCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTTCGATACTCCTTAGCGGTACTTGCTAAAGTAGTTCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACAAATAATTCTTGTGACTCACGTGCCGCCATTTGAACCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTAGGAATTGATTGGGGTAACGCCATCGCCATAGAAGCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTTACTTCATGACCCGGACATTTTACTAAAAAATTCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTCCTATACCTTGTCACAATTTCCTCATATGGCTCCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACCATAATTGGGAATTGGTGTGAAATGCTCACCGTCCGCCAATAATCCCTCATCTAAAAATCCAACCACTGAAACTTAATTGCGCCAGAAACAGCACCATTTATGGTTACAGCCCAATAATCCCTCATCTAAAAATTTAACTAATGAAAT

>NC_006368|1|1|190034-192439|CRISPRCasFinder
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TAGATATAAAAAGATTAAATCTTCTAGCGCACAT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCACTACTCCTGAAGGTTATAATTTTTGCTATAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTCGAATACAATCCTAGTGTCTCTGTGTGAATTAAG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CAGGCACTGGTTCACTAGACACTGTAACATCTAT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CAATAACAAGCGAGCCTTTTGTACTAGAAGGTTTA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTACCAGTTAATCGTAACTCAATCTCTTTTTCAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATAGAATACATAAGTGCAAATTATTAAATGTTAC
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TGAATGTAGAAACCAGATGCCACGAATTATTAGA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTTGTATAAACGTTCTGATATGACTTAGGTAATCT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTAACCTGATTGCTCAACAAATAATGCTATTGGC
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCACTTTAGGCCAACGCCGATCCTCCGCTTCGAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TGACGCAAAGGATTTATTAAAAACGCCTTGTAAT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATTTTACCTTTTAACACATATTGATAGGCGT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCCATAACTGAAACGTCCTTATGCCTCAACATAATG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GAATTTGTCGGCCGCATAGACCGCTTTTATCAAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTATTGCAAGCTAGTTTGATCGTGTTATTATAAGAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TGACAAACGTTTGTTTTTTAGACACAACACTAAAAG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CCTGAAAACCCGCCACAACCCGCGCCAGACTTGAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ACCAAGTCGAAACAACATACCGAGACCGTGTTGA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TACATTGTTACGTTCATTTCACTCAGTTTTTCATA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AGCAATAACCCAAAGTTTCGCGCGCGTGCGCGGG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTATAACATCGGGATGGCGGTTTATTGGTTAAGTAAC
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTCTTTTTTCAGATTTCATTTCCTTTTCCTTGTG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AATCTTAATTTATGCGCCTTACCTTCTGCTTCATC
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TATACTTAGACAATATCATCATTTCCTATGTTTCGA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GCTATTCCAGATAGGTAGTTGTTTAGAGCATTTTGT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTCGATACTCCTTAGCGGTACTTGCTAAAGTAGTT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AAATAATTCTTGTGACTCACGTGCCGCCATTTGAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TAGGAATTGATTGGGGTAACGCCATCGCCATAGAAG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTACTTCATGACCCGGACATTTTACTAAAAAAT
TCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCCTATACCTTGTCACAATTTCCTCATATGGCTC
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CATAATTGGGAATTGGTGTGAAATGCTCACCGTCCG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTAATTGCGCCAGAAACAGCACCATTTATGGTTACAGC
CCAATAATCCCTCATCTAAAAATTTAACTAATGAAAT

>NC_006368|1|1|190034-192439|CRT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TAGATATAAAAAGATTAAATCTTCTAGCGCACAT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCACTACTCCTGAAGGTTATAATTTTTGCTATAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTCGAATACAATCCTAGTGTCTCTGTGTGAATTAAG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CAGGCACTGGTTCACTAGACACTGTAACATCTAT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CAATAACAAGCGAGCCTTTTGTACTAGAAGGTTTA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTACCAGTTAATCGTAACTCAATCTCTTTTTCAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATAGAATACATAAGTGCAAATTATTAAATGTTAC
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TGAATGTAGAAACCAGATGCCACGAATTATTAGA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTTGTATAAACGTTCTGATATGACTTAGGTAATCT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTAACCTGATTGCTCAACAAATAATGCTATTGGC
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCACTTTAGGCCAACGCCGATCCTCCGCTTCGAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TGACGCAAAGGATTTATTAAAAACGCCTTGTAAT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ATTTTACCTTTTAACACATATTGATAGGCGT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCCATAACTGAAACGTCCTTATGCCTCAACATAATG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GAATTTGTCGGCCGCATAGACCGCTTTTATCAAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CTATTGCAAGCTAGTTTGATCGTGTTATTATAAGAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TGACAAACGTTTGTTTTTTAGACACAACACTAAAAG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CCTGAAAACCCGCCACAACCCGCGCCAGACTTGAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	ACCAAGTCGAAACAACATACCGAGACCGTGTTGA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TACATTGTTACGTTCATTTCACTCAGTTTTTCATA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AGCAATAACCCAAAGTTTCGCGCGCGTGCGCGGG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTATAACATCGGGATGGCGGTTTATTGGTTAAGTAAC
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTCTTTTTTCAGATTTCATTTCCTTTTCCTTGTG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AATCTTAATTTATGCGCCTTACCTTCTGCTTCATC
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TATACTTAGACAATATCATCATTTCCTATGTTTCGA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	GCTATTCCAGATAGGTAGTTGTTTAGAGCATTTTGT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTCGATACTCCTTAGCGGTACTTGCTAAAGTAGTT
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	AAATAATTCTTGTGACTCACGTGCCGCCATTTGAA
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TAGGAATTGATTGGGGTAACGCCATCGCCATAGAAG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTACTTCATGACCCGGACATTTTACTAAAAAAT
TCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TCCTATACCTTGTCACAATTTCCTCATATGGCTC
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	CATAATTGGGAATTGGTGTGAAATGCTCACCGTCCG
CCAATAATCCCTCATCTAAAAATCCAACCACTGAAAC	TTAATTGCGCCAGAAACAGCACCATTTATGGTTACAGC
CCAATAATCCCTCATCTAAAAATTTAACTAATGAAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_006368.1\|WP_011212792.1\|183830_187949_+\|type-II-B-CRISPR-associated-RNA-guided-endonuclease-Cas9/Csx12	cas9	cd09704_cas9_CAS-II-B	gnl\|CDD\|187835
NC_006368.1\|WP_011212790.1\|178778_180113_+\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_011212804.1\|199245_199392_+\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_021437111.1\|194888_195251_+\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_025519199.1\|180212_182228_+\|M3-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341051
NC_006368.1\|WP_011212797.1\|194053_194923_+\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_011212788.1\|175441_176434_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|223135
NC_006368.1\|WP_011212789.1\|176514_178521_-\|transketolase	unknown	unknown	gnl\|CDD\|223100
NC_006368.1\|WP_011212799.1\|195263_195467_+\|carbon-storage-regulator	unknown	unknown	gnl\|CDD\|376847
NC_006368.1\|WP_011212793.1\|187945_188938_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187766
NC_006368.1\|WP_011212802.1\|196043_198524_+\|VirB4-family-type-IV-secretion/conjugal-transfer-ATPase	unknown	unknown	gnl\|CDD\|273346
NC_006368.1\|WP_104411317.1\|195481_195766_+\|TrbC/VirB2-family-protein	unknown	unknown	gnl\|CDD\|368210
NC_006368.1\|WP_011212801.1\|195775_196057_+\|VirB3-family-type-IV-secretion-system-protein	unknown	unknown	gnl\|CDD\|368285
NC_006368.1\|WP_011212803.1\|198520_199231_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271354
NC_006368.1\|WP_025519205.1\|193217_193892_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224885
NC_006368.1\|WP_011212795.1\|189224_189818_+\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768
NC_006368.1\|WP_126297580.1\|183034_183355_+\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_011212794.1\|188944_189244_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_006368.1\|WP_021437110.1\|192790_193228_+\|DUF45-domain-containing-protein	unknown	unknown	gnl\|CDD\|307807
NC_006368.1\|WP_011212787.1\|174240_175431_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613

Protein	Function_ID	Function_description	E-value
NC_006368.1\|WP_011212792.1\|183830_187949_+\|type-II-B-CRISPR-associated-RNA-guided-endonuclease-Cas9/Csx12	gnl\|CDD\|187835	cd09704, Csx12, CRISPR/Cas system-associated protein Cas9. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Very large protein containing McrA/HNH-nuclease related domain and a RuvC-like nuclease domain; signature gene for type II.	0
NC_006368.1\|WP_104411317.1\|195481_195766_+\|TrbC/VirB2-family-protein	gnl\|CDD\|368210	pfam04956, TrbC, TrbC/VIRB2 family. Conjugal transfer protein, TrbC has been identified as a subunit of the pilus precursor in bacteria. The protein undergoes three processing steps before gaining its mature cyclic structure. This family also contains several VIRB2 type IV secretion proteins. The virB2 gene encodes a putative type IV secretion system and is known to be a pathogenicity factor in Bartonella species.	2.57003e-10
NC_006368.1\|WP_011212801.1\|195775_196057_+\|VirB3-family-type-IV-secretion-system-protein	gnl\|CDD\|368285	pfam05101, VirB3, Type IV secretory pathway, VirB3-like protein. This family includes the Type IV secretory pathway VirB3 protein, that is found associated with bacterial inner and outer membranes. The family also includes the conjugal transfer protein TrbD family that contains a nucleotide binding motif and may provide energy for the export of DNA or the export of other Trb proteins.	7.62347e-18
NC_006368.1\|WP_025519199.1\|180212_182228_+\|M3-family-metallopeptidase	gnl\|CDD\|341051	cd06456, M3A_DCP, Peptidase family M3, dipeptidyl carboxypeptidase (DCP). Peptidase family M3 dipeptidyl carboxypeptidase (DCP; Dcp II; peptidyl dipeptidase; EC 3.4.15.5). This metal-binding M3A family also includes oligopeptidase A (OpdA; EC 3.4.24.70). DCP cleaves dipeptides off the C-termini of various peptides and proteins, the smallest substrate being N-blocked tripeptides and unblocked tetrapeptides. DCP from Escherichia coli is inhibited by the anti-hypertensive drug captopril, an inhibitor of the mammalian angiotensin converting enzyme (ACE, also called peptidyl dipeptidase A). OpdA may play a specific role in the degradation of signal peptides after they are released from precursor forms of secreted proteins. It can also cleave N-acetyl-L-Ala. This family also includes Arabidopsis thaliana organellar oligopeptidase OOP (At5g65620), which plays a role in targeting peptide degradation in mitochondria and chloroplasts; it degrades peptide substrates that are between 8 to 23 amino acid residues, and shows a weak preference for hydrophobic residues (F/L) at the P1 position.	0
NC_006368.1\|WP_011212788.1\|175441_176434_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	1.0658e-170
NC_006368.1\|WP_011212789.1\|176514_178521_-\|transketolase	gnl\|CDD\|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NC_006368.1\|WP_011212799.1\|195263_195467_+\|carbon-storage-regulator	gnl\|CDD\|376847	pfam02599, CsrA, Global regulator protein family. This is a family of global regulator proteins. This protein is a RNA-binding protein and a global regulator of carbohydrate metabolism genes facilitating mRNA decay. In E. coli CsrA binds the CsrB RNA molecule to form the Csr regulatory system which has a strong negative regulatory effect on glycogen biosynthesis, glyconeogenesis and glycogen catabolism and a positive regulatory effect on glycolysis. In other bacteria such as Erwinia caratovara RmsA has been shown to regulate the production of virulence determinants, such extracellular enzymes. RmsA binds to RmsB regulatory RNA.	3.39121e-14
NC_006368.1\|WP_011212793.1\|187945_188938_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.39666e-79
NC_006368.1\|WP_011212802.1\|196043_198524_+\|VirB4-family-type-IV-secretion/conjugal-transfer-ATPase	gnl\|CDD\|273346	TIGR00929, CAG_pathogenicity_island_protein_23, type IV secretion/conjugal transfer ATPase, VirB4 family. Type IV secretion systems are found in Gram-negative pathogens. They export proteins, DNA, or complexes in different systems and are related to plasmid conjugation systems. This model represents related ATPases that include VirB4 in Agrobacterium tumefaciens (DNA export) CagE in Helicobacter pylori (protein export) and plasmid TraB (conjugation).	0
NC_006368.1\|WP_011212803.1\|198520_199231_+\|hypothetical-protein	gnl\|CDD\|271354	cd14262, VirB5_like, VirB5 protein family. This family contains VirB5 domains, including TraC, a VirB5 homolog encoded by the pKM101 plasmid, and similar proteins. VirB5 is one of 11 conserved proteins (VirB1-VirB11) in Agrobacterium tumefaciens, the causative agent of crown gall disease, that span the inner and the outer membrane, and is involved in type IV DNA secretion systems (T4SS) which mediate the translocation of virulence factors (proteins and/or DNA) from Gram-negative bacteria into eukaryotic cells. VirB5 assembles extracellular pili by interacting with several essential proteins. VirB2-VirB5 complex formation precedes incorporation into pili; it depends on the inner membrane protein VirB4 to interact directly with and stabilize VirB8 in order for VirB5 to bind to VirB8 and VirB10. Mutagenesis studies show that VirB5 proteins participate in protein-protein interactions important for pilus assembly and function.	1.73105e-17
NC_006368.1\|WP_021437110.1\|192790_193228_+\|DUF45-domain-containing-protein	gnl\|CDD\|307807	pfam01863, DUF45, Protein of unknown function DUF45. This protein has no known function. Members are found in some archaebacteria, as well as Helicobacter pylori. The proteins are 190-240 amino acids long, with the C-terminus being the most conserved region, containing three conserved histidines. This motif is similar to that found in Zinc proteases, suggesting that this family may also be proteases.	3.33417e-41
NC_006368.1\|WP_011212795.1\|189224_189818_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	7.69466e-15
NC_006368.1\|WP_011212794.1\|188944_189244_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.29256e-05
NC_006368.1\|WP_025519205.1\|193217_193892_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224885	COG1974, LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms].	1.18895e-16
NC_006368.1\|WP_011212787.1\|174240_175431_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0

>NC_006368.1|WP_011212795.1|189224_189818_+|CRISPR-associated-protein-Cas4
MDTSSYKLPVNMIRQYCFCPRIVYYHMVVGLKVAYPGWVQYGEEYQHKQQVLDKRRTLSKFKPISEQAVLRQNTMLEHPSYPFYGICDGIIEDELEIIPIELKSFASKISLGQKMQLTAYGMLSELIFEKPCTRGYIITGEKAKAKLIKIDEKSKFKVIEICAKIKKIFGTETLPYSTANGLQCIQCEFLNHCNDRF
>NC_006368.1|WP_011212794.1|188944_189244_+|CRISPR-associated-endonuclease-Cas2
MQIRLYKEYIVSYDIRDNSIRRTIYERLKDIGLTPVQKSVFWGYLNEPEKRYLTNFLKKELAKQDTAFITPCKLAQEYEVNLINLELDELRKPDGHIIV
>NC_006368.1|WP_011212793.1|187945_188938_+|CRISPR-associated-endonuclease-Cas1
MKHLTLSEQGSFCKLQGERILVFNKDQMVFEGTLNRLKTISIVKQGVTLTSNLLVACAMRGIQIFILDYSGKAVCSLQGGLHRTAKVRESQFKYIYTKEASNMAARFILAKIKKQSAVLKYFAKAKNRPENEKIILHAASQKMAGIVANITETNWIKLQDWRFTLLGFEGSAARIYWETVKEVNLVCSDFEGRRPRVNKDITNSMLNYAYSILSSWVWQAITNAGLELYAGILHTSKPGKPSLVLDLMEEFRPWCADRIIFKLHARAQKQNELTPALKKTLIGEMANLYAKPLPYHKRRISLESIIQRQVYHLSAVFSGEGKYKGYLFKW
>NC_006368.1|WP_011212792.1|183830_187949_+|type-II-B-CRISPR-associated-RNA-guided-endonuclease-Cas9/Csx12
MESSQILSPIGIDLGGKFTGVCLSHLEAFAELPNHANTKYSVILIDHNNFQLSQAQRRATRHRVRNKKRNQFVKRVALQLFQHILSRDLNAKEETALCHYLNNRGYTYVDTDLDEYIKDETTINLLKELLPSESEHNFIDWFLQKMQSSEFRKILVSKVEEKKDDKELKNAVKNIKNFITGFEKNSVEGHRHRKVYFENIKSDITKDNQLDSIKKKIPSVCLSNLLGHLSNLQWKNLHRYLAKNPKQFDEQTFGNEFLRMLKNFRHLKGSQESLAVRNLIQQLEQSQDYISILEKTPPEITIPPYEARTNTGMEKDQSLLLNPEKLNNLYPNWRNLIPGIIDAHPFLEKDLEHTKLRDRKRIISPSKQDEKRDSYILQRYLDLNKKIDKFKIKKQLSFLGQGKQLPANLIETQKEMETHFNSSLVSVLIQIASAYNKEREDAAQGIWFDNAFSLCELSNINPPRKQKILPLLVGAILSEDFINNKDKWAKFKIFWNTHKIGRTSLKSKCKEIEEARKNSGNAFKIDYEEALNHPEHSNNKALIKIIQTIPDIIQAIQSHLGHNDSQALIYHNPFSLSQLYTILETKRDGFHKNCVAVTCENYWRSQKTEIDPEISYASRLPADSVRPFDGVLARMMQRLAYEIAMAKWEQIKHIPDNSSLLIPIYLEQNRFEFEESFKKIKGSSSDKTLEQAIEKQNIQWEEKFQRIINASMNICPYKGASIGGQGEIDHIYPRSLSKKHFGVIFNSEVNLIYCSSQGNREKKEEHYLLEHLSPLYLKHQFGTDNVSDIKNFISQNVANIKKYISFHLLTPEQQKAARHALFLDYDDEAFKTITKFLMSQQKARVNGTQKFLGKQIMEFLSTLADSKQLQLEFSIKQITAEEVHDHRELLSKQEPKLVKSRQQSFPSHAIDATLTMSIGLKEFPQFSQELDNSWFINHLMPDEVHLNPVRSKEKYNKPNISSTPLFKDSLYAERFIPVWVKGETFAIGFSEKDLFEIKPSNKEKLFTLLKTYSTKNPGESLQELQAKSKAKWLYFPINKTLALEFLHHYFHKEIVTPDDTTVCHFINSLRYYTKKESITVKILKEPMPVLSVKFESSKKNVLGSFKHTIALPATKDWERLFNHPNFLALKANPAPNPKEFNEFIRKYFLSDNNPNSDIPNNGHNIKPQKHKAVRKVFSLPVIPGNAGTMMRIRRKDNKGQPLYQLQTIDDTPSMGIQINEDRLVKQEVLMDAYKTRNLSTIDGINNSEGQAYATFDNWLTLPVSTFKPEIIKLEMKPHSKTRRYIRITQSLADFIKTIDEALMIKPSDSIDDPLNMPNEIVCKNKLFGNELKPRDGKMKIVSTGKIVTYEFESDSTPQWIQTLYVTQLKKQP
>NC_006368.1|WP_126297580.1|183034_183355_+|hypothetical-protein
MMNDLAKILSLKNLLTKNNINPSENFENIYSQITDDGLKKEIESRIIDYFSKLSLPEHVTIYDQLLLSLREKDAISHSNGIYFYLTHIKEIVILFHCLRYFSCMVM
>NC_006368.1|WP_025519199.1|180212_182228_+|M3-family-metallopeptidase
MSTTVGLPQFSHIKIEHFKSHLDALLKNHLEEIDRLLKENHHYTWDNLIYPLDSLADELERFWSPFAHMHAVMDSEAIRESYETCLPLLSAYDAAIGHNQDLYEAIKSIDQHSLNPAQKKIIEDSMQDFELSGVALSKANKKRFEAIQSRLAELSSKFENNVLDATHAYTIHITEAERVAGLPEHALNTAKELAHEKGLDGFVLTLEYPCFQAVITHAEDRALREEMYRAYITRASDQGPNAGTFDNTPLIDEILSLRHEKAELLGFNNFAELSLATKMAASTNQVTEFIYDLISRTRDKGKAEFRQLEVFAQDKWNLSPVNPWDVAYLSEKRRQDLYSLSQEELRPYFPQPKVMQGLFAIVKKLFGMSIEEIEGVDVWHKDVQCYCIVDESNQTRGYIYTDLFARPHKRNGAWMDSMQSRRKLEDGTVQLPIATLTCNFAKPSANRPAMLSHDEVVTLFHEFGHCLHHVLTQVDYLGGSGINGVEWDAVELPSQFFENWCWDEHALSLLTSHVDTGETLPSALYERLIAAKNFQSAMAMLRQMEFALFDFRIHQEYQIGKASYVANILADVRSKTSVVPIVPYNRFQHSFSHIFGGGYAAGYYSYMWAEVLSSDAFARFEEEGIFNPKTGHDFLKSILEAGGSRKAADAFAEFRGRPATIDALLRHNGIL
>NC_006368.1|WP_011212790.1|178778_180113_+|hypothetical-protein
MTPIISHLLKIFPELNTQVKTDSLNWTFSTHLKQLGPDFYSKIARLHPILNMEYSVLCQRLRYNLSAPDYSSPEQIKEQLIDALKLAELLEYTYQHYLVVPREVVRLRRHKAIYRELLTELSGYSFALDNPEPESLKTSLSLTQAIREKTAQSNWYRIFISRSKRVINLLDNLDTGSKAFRDFVVLLDKYTNPFLAYLGWCFFAPRLFTNLFLILKHTIPGEWMGEKEKSLDWSDRFYAHLQRRWFELANDSVWFTVGILNCFVLVGALAPLSVYLSLFAFVFDVANTSLRAYIEIGRLQQLQKEYAELFDQEENEDQKKIIKEYQDSISYRIKFEILRSFLSVGGAVAVVIAMALSVPALGIINPVIPLIGAVLLLALWGVSLYLNNKLDEYRPVDNIEKPAPSVINKLSFFAPKNEKKESLHLSSKPEKDLEAEELIPTFTF
>NC_006368.1|WP_011212789.1|176514_178521_-|transketolase
MNSFTELANAVRMLSIDAVNQAQSGHPGMPLGMADIATVLWKKFLKFNPKNPHWFNRDRFVLSNGHGSMLLYSLLHLTGYNLDINELKNFRQLHSKTPGHPEHGHTPGVETTTGPLGQGLANSVGMALAERVLASHFNHDHYNLVDHYTYTFAGDGCLMEGISHEACSLAGTLGLGKLIVFYDDNGISIDGKVESWFTDDTTSRFKAYNWQVIGPIDGHDADQIEQAISAARENTTQPSLIICKTVIGLGSSVAGSEKAHGSPLSAQDINNVREFFNWKHAPFEIPDSIYKQWDHREQGDKEEQQWLQLLHEYRLQYPSEHDEFLRRANGDLPDDWQEISAGFLKQCLNNEKAIATRKASQQCIEFFAPILPEMFGGSADLTGSNNTDWSGSKAITAHNFSGNYLYYGVREFAMAAIMNGLAVHGGFIPYGGTFLVFADYARNAIRLSALMKQRVIYVLTHDSIGLGEDGPTHQPIEHIAMLRMTPGMTVWRPADLMETAVAWQQSLEHHNGPSALLLSRQNLPALAHGTDAADLIKKGGYIIADCEGKPDAILIATGSEVQLAITAAEKAKARGLQVRVVSMPCAERFLAQSDAYKNQVLPGQVRTRIAIEAASSAYWHQFVGFDGAVIGLDCFGVSAPATDAFNYLGITVEKIINTLDTLTKQTMV
>NC_006368.1|WP_011212788.1|175441_176434_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTIRVAINGYGRIGRCILRSIFEYNRQNEFEVVAINDLSGIDVTAHLTRYDSTHGPFRSDVSIEGNMLIVDGHGIQVIAERDPAKLPWKQLDIDIVFECTGFFTSRDAAMGHINAGAKKVLISAPAKGVDTTVVYGVNHSVIKASDVIVSNASCTTNCLAPVVKVLNDAIGIESGLVNTVHAYTKDQMLLDGSHKDLRRARSATQSIIPTKTGAAAAVGLVLPELAGKLDGFAMRVPVLNVSVVDLTFQAKRATSVEEVNDIMRKAKSRILQINEDPLVSCDFNHNPASAIFDTTETKVIGSLVKVVAWYDNEWGFSNRMIDTAHQMMNC
>NC_006368.1|WP_011212787.1|174240_175431_-|phosphoglycerate-kinase
MNLIKMSDIDLSGKRVLIREDLNVPIKDGMITSDQRLQAALPTIKSALDNGAAVIVLSHLGRPEEGKYEKKFSLEPVADYLRKNLEYPVRFVKDYLSGVDVKPGELVVCENVRFNPGEKANDEALAKKLANLCDVFVMDAFGTAHRAQASTYGVAQYAPVAVAGPLLIRELEALNQVLKAPKKPIVAIVGGAKVSSKLSLLKQLVGMVDVLIPGGGIANTFLKAQGFEIGISLYEPDLLDEARHILILAKEKGCQIPLPTDVVVGKTFSETCPAFNKSLSNVAEDDMILDIGPETIRDYVDLIHEANTIIWNGPVGVFEFPQFAYGTRAIAIAIAESDAFSIAGGGDTLAAVDLYDLNQQISYISTGGGAFLECLEGKTLPAVAILQERAKHVKTN
>NC_006368.1|WP_021437110.1|192790_193228_+|DUF45-domain-containing-protein
MIDDSKAKPQVKLVRGQLQIIASRNIEHRRQLLSDWYKQKAFEVFSKRLDQLLSTAPWIKECPSINLRAMRSRWGSCAVNGKITLNTHLIKAPIACIDYVILHELCHHFEHNHSDKFYRLLNQVSPNWKQVKQYLDKAANLYLMT
>NC_006368.1|WP_025519205.1|193217_193892_-|helix-turn-helix-domain-containing-protein
MNIKKEIGKRILEARKAKGLTLKALGELAGGLKQTRLTNWEQGVRTPGPEEIKSLARALDVSPAYLMCLSDELQFKEAKNPSQLIPLLDYRQACEASLHTGAESSGDKVFISVSTSLQPELSTDAFALKITDDSMMPEIRINDVLVIEPSVLPEPGDFVAVKINGKPETIICQYKKLSYTSSEFELLTLNDNWPNIKVSDDINVKIIGVLVQNLRCYKSPKVKS
>NC_006368.1|WP_011212797.1|194053_194923_+|hypothetical-protein
MMDFVINGDELEAMSGLPHFQQLTYLRGIRPYMDVKTGIVGIKRRISHQSISEQLYVEPHQGIKSQNFSRDQVRRSVSGLVRAGLIEVQSEGMHLILKCLLASSHYSAQNKAAINPPQKATIKPRGESLENTGLTEFEALKADTVESQKAAIPHKDNYYIYLLSQFEKFWSLYPEKKSKNNAQAVFEELKPNAELCHTIINALTAQINYRDTMKLQGTWVPPWKYPANWLAQRCWEDELPTDALQEKNHAEHTKNTRKRHATEDLFCPPCDVKDREHNNVIQLQRYLQS
>NC_006368.1|WP_021437111.1|194888_195251_+|hypothetical-protein
MSSSSKDTFKAERRIDLLFSKFAAFYGHVWRSQFKDEVFLKFAKKEWQEALADFTDMVLTRAILNCREFYELPPTLPQLLYCCRQIRKQESFYVVKDVYQPANKAVVSSCLQKCKELLAK
>NC_006368.1|WP_011212799.1|195263_195467_+|carbon-storage-regulator
MLVLTRKAGQQILIGKGLIQMKVLKVENDIISIGIKAPSHIDIDREEIYFRKLRQEQEAANDAEMAI
>NC_006368.1|WP_104411317.1|195481_195766_+|TrbC/VirB2-family-protein
MSKRAFQKIRTLYWGTVCLCAPSVSSAQNIESIINRTINYLQGGLARTVGVFCIIIAGYLCLARQKFPKEYFVMILVGMGIIFGGSSLYSTLIG
>NC_006368.1|WP_011212801.1|195775_196057_+|VirB3-family-type-IV-secretion-system-protein
MSDLEISPIFNALTRPAMTAGVTFEYHMLNLIVSMCAFIGFSPLYGIIFIPLHVFGWLVCRYDTHFFTICAKRFLLPQAPNTSLWRVRAYEPF
>NC_006368.1|WP_011212802.1|196043_198524_+|VirB4-family-type-IV-secretion/conjugal-transfer-ATPase
MNLSKTLKHVYQEAKVSNLFPVTHLNSPCIFESQSGLVGSVIKVNGAAFEIEEAETLNHQRFLLHQALVSLDSRFIIYVTTHRQKISCPLIGEFKPGFAKDLDERYQQRFKDKNLYKNTLYITVVLKGDDTSKTGSWLQWAKSLSMKGNSELAEHHREQNIQILNRAVEQLHTNLNSFGASILGMQDEELGFSELLQFLGLVVNAGQTASFKHPVYSPPIANSIPQTFKQEAKYPEGHLGQYLSSCQLLFGECIQFQGNTQQDCLFGAMLSLKKYPTNTASILLDSMLSLDCEFIATHTFAPIGRDSALDTISKKRSKLLNAEDKALSQTTALTDLEDGIASETLLLGAHHHTVMLLAPNKSLLDAAILEATKRYGATGVVVVKETLGQEPAFWSQLPCNQHFITRASLITSQNFVDFCPLHNTQTSFSNENFLGGAVTLLETPSKTPVYFNYHARGSKTNPSKGHAAIFGGNNAGKTTLVNFLDAQMGRFGGRSFFIDRDESSKIYILASGNSSYIKIEPSNPIAMNPLQLPDTSENRSFLKSWFATLVQEDSERAIPSPIAEIINDCIDYSFEQLAPEFRTLSHLSQFLPVDFPRWPHLKRWLKRNDSRIDGEFHWLFDNQHDALNLDFDKVGFDVTYLMDQVQSIIATPVYLYLLHRMRQCLDGRLTSFIIAEAWQLFASPFWEKALREWLPTIRKKNGHFIFDTQSPKTITDSPIKHIVLDNLATLIAFPNPLADKETYMEHLKLTEAQFEAIKENTPESRIFLYKQDHEAFLCKLDLSGLSQYIRVLSANTQSVKLLDDIMQEVGHDPELWLPVFFERSKK
>NC_006368.1|WP_011212803.1|198520_199231_+|hypothetical-protein
MKRTACFLIAVLGISGASHADILGVEDAQLIVLAMKQLGELQEQYRVLTDTYQTTRSQLDNLNQLKSMNSGHYGFGDFNNGLDTLQSWQSPVSTWQDALENLSGGNQQRYQALMDAYEKNHPSLDESSYARFTTPANVARFKEDKAVNRAVLVQTTESYNEINKHMEALHKLSQQIEKTPNTKGAIDLNSRLITEIGFIQLMSLRLQALISQQAAQENLSALQDRAEMAKFNRLPK
>NC_006368.1|WP_011212804.1|199245_199392_+|hypothetical-protein
MKWLLSVLMIALLSGCSKPPDLDSPCHHFGQYCPQYPINDEPIMELTK

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Crispr_ID: NC_006368_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006368_2

2315678-2315806

Unclear

Consensus_repeat	Method
CTATTCTTAATGCTCAACAGAATAAAAAACAACAGA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of NC_006368_2

>merge|NC_006368|2|2315678-2315806|CRISPRCasFinder
CTATTCTTAATGCTCAACAGAATAAAAAACAACAGACAAATAGTCCATCTAAAGAGATAAAAAAATTTGATATGTCAGAAGCTCAATTATGGGCTATTCTTAATGCTCAACAGAATAAAAAACAACAGA

>NC_006368|2|2|2315678-2315806|CRISPRCasFinder
CTATTCTTAATGCTCAACAGAATAAAAAACAACAGA	CAAATAGTCCATCTAAAGAGATAAAAAAATTTGATATGTCAGAAGCTCAATTATGGG
CTATTCTTAATGCTCAACAGAATAAAAAACAACAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_006368.1\|WP_015961262.1\|2305901_2306213_+\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_015961277.1\|2328666_2330421_-\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NC_006368.1\|WP_015961263.1\|2307400_2308807_+\|ATP-dependent-RNA-helicase-DbpA	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236977
NC_006368.1\|WP_010947832.1\|2306951_2307161_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_006368.1\|WP_015961265.1\|2310563_2311646_-\|acetamidase/formamidase-family-protein	unknown	unknown	gnl\|CDD\|225279
NC_006368.1\|WP_011213396.1\|2302583_2303759_-\|ISL3-like-element-ISLpn11-family-transposase	unknown	unknown	gnl\|CDD\|376574
NC_006368.1\|WP_010946556.1\|2317758_2318052_-\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198395
NC_006368.1\|WP_015961274.1\|2323928_2325671_+\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NC_006368.1\|WP_013101666.1\|2322299_2322590_-\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198395
NC_006368.1\|WP_011946955.1\|2310146_2310548_-\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_015961264.1\|2308963_2309875_+\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|226474
NC_006368.1\|WP_015961270.1\|2318077_2318863_-\|transposase	unknown	unknown	gnl\|CDD\|376573
NC_006368.1\|WP_015961268.1\|2313170_2315123_-\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_015961275.1\|2326168_2327248_+\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_021437119.1\|2317323_2317587_-\|transposase	unknown	unknown	gnl\|CDD\|379129
NC_006368.1\|WP_015961276.1\|2327546_2328452_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_006368.1\|WP_031285541.1\|2303824_2305582_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|213656
NC_006368.1\|WP_011946965.1\|2320235_2322056_+\|NADAR-family-protein	unknown	unknown	gnl\|CDD\|271319
NC_006368.1\|WP_015961271.1\|2319044_2319797_-\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_015961266.1\|2311679_2312429_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129

Protein	Function_ID	Function_description	E-value
NC_006368.1\|WP_015961277.1\|2328666_2330421_-\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	1.61648e-30
NC_006368.1\|WP_015961263.1\|2307400_2308807_+\|ATP-dependent-RNA-helicase-DbpA	gnl\|CDD\|236977	PRK11776, PRK11776, ATP-dependent RNA helicase DbpA; Provisional.	0
NC_006368.1\|WP_010947832.1\|2306951_2307161_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	3.52513e-27
NC_006368.1\|WP_015961265.1\|2310563_2311646_-\|acetamidase/formamidase-family-protein	gnl\|CDD\|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	3.77303e-65
NC_006368.1\|WP_011213396.1\|2302583_2303759_-\|ISL3-like-element-ISLpn11-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	4.15326e-65
NC_006368.1\|WP_010946556.1\|2317758_2318052_-\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198395	cd10448, GIY-YIG_unchar_3, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	8.91238e-49
NC_006368.1\|WP_015961274.1\|2323928_2325671_+\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	2.24987e-25
NC_006368.1\|WP_013101666.1\|2322299_2322590_-\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198395	cd10448, GIY-YIG_unchar_3, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	7.59333e-49
NC_006368.1\|WP_015961264.1\|2308963_2309875_+\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|226474	COG3965, COG3965, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	4.52401e-101
NC_006368.1\|WP_015961270.1\|2318077_2318863_-\|transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	8.3072e-05
NC_006368.1\|WP_021437119.1\|2317323_2317587_-\|transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	3.24622e-15
NC_006368.1\|WP_015961276.1\|2327546_2328452_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	2.3121e-37
NC_006368.1\|WP_031285541.1\|2303824_2305582_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	5.27136e-146
NC_006368.1\|WP_011946965.1\|2320235_2322056_+\|NADAR-family-protein	gnl\|CDD\|271319	cd15457, NADAR, Escherichia coli swarming motility protein YbiA and related proteins. This family of uncharacterized domains was initially classified as Domain of Unknown Function (DUF1768). It contains members such as the E. coli swarming motility protein YbiA. Mutations in YbiA cause defects in Escherichia coli swarming, but not necessarily in motility. More recently, this family has been predicted to be involved in NAD-utilizing pathways, likely to act on ADP-ribose derivatives, and has been named the NADAR (NAD and ADP-ribose) superfamily.	8.07957e-10
NC_006368.1\|WP_015961266.1\|2311679_2312429_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.56145e-19

>NC_006368.1|WP_015961268.1|2313170_2315123_-|hypothetical-protein
MPHSTNQSNVIENINQYLKWHNLPVRFGTGGVCNGLSTVHAQYVLQGREREFFELLRYVAGDKGILDANDSVKEKVNDFVWKVVASHMTSGHDKELNQLNSFKTLSINNKPLKSVFDLPLVTSDKNWENILESLNLKEDEVMLVRSINHAISITRKGNQYHVYDPNYEEGVKSFSSEQEVIKELHERVFHYNKGNMGLTLSIITTGDKEPRQDLPKPVDIYDQYLNKENVNSLATITVEHPLGGPWDLTKKTIDLASECGDENLINKLIELHQFDFNNMPIEQASQAVQYNNVRAAELLVNDMIRILSKQDPVAQDEFSDIPAEELPAEFLKQFEEIPDAPEGDEIKEAEVQNPKVVMPPSEKKIKDLLYPLILKAASYGRKEVFDTLCEMWNKNAGDFDKEDLKNFILLAAKGGNSVLLQELIDKYYESNMTLYDKDIQGKVDGIIHELISKGSPDSAVCIEVLLNTLSKEGKSIDDRQRADYISRAFEANKPHMIERFIKGISDEKRLEFLIRAIKKDQPHMVELFIKDLPKGLLNTISLSLPAIEKMNGETLKILEKNGMKFTEMEKAIIAKKSHQPVGLLLSIGVALAKFTDFCKEVLFKNESVTYDKNKFQAFKSQLNSIKTQNSLANNEPVEAQQNDQVAVYRP
>NC_006368.1|WP_015961266.1|2311679_2312429_-|IS5-family-transposase
MHHNISEELWNKIYSYLRGLKGLHVKNEASLRRFIEGVWYVLRTGCQWRLLPYYYGHWRQIHRRYKVWSDRGIWSELMSVVSDVDIQTVMIDATIVRAHACASGYVKDGNETQALGRSKGGFTTKIHALVDGVGNPIKFILTGGHRNDITQAAELLKEQHDTIVLADKGYDSQELIDTLHHQRCSPVIPSRKNSKYPRKIDKQLYKERFLTEAFFSKLKHFRRIFSRFDKTTSAFSGFLHLAGALIWMR
>NC_006368.1|WP_015961265.1|2310563_2311646_-|acetamidase/formamidase-family-protein
MDKTPVVKVHSGDSVSLETWNSCLHEMVFNKTTPAEIAKFYTKHDIQKRRGMHSLTGPVYVEGAEPGDVLEIRVLDIKLNDFGYNFLSPTQGILSEFTKPRIMYFKYDKEKNTTEFTKGICLHLKPFQGIIAVAPPLDWPDGWPVNLETQMGQPVPGQFNSVPPGPFGGNLDEPSLQVGSILYLPVFQKGALVWTGDSHAMQSNGEIDVTALETSFEGITLQFIVRKDLKAEGVFDKTKRNGNSLFTWPIVENSEEWILIGLHENLFEAMQLASKNAIEFLVRTQGLSSQESYQFLSMVGNFDIPEAVNVIKSLAVHIPKEIFKNTGKMTSLSSEGKFPLTTPRTNENTTCVPQEGKIIE
>NC_006368.1|WP_011946955.1|2310146_2310548_-|hypothetical-protein
MNKILIYLCLYFMTSITLAGKIVIDNKTNYPVKDNSRKIAVQWVATVEATQKANKIIINGSKLDLSSLKIITQKGKTQLTLPNHSHYFRVVVWSTGKQQPDLLTNWVDIVPNKTYIINQDQLVPAILMSGTGC
>NC_006368.1|WP_015961264.1|2308963_2309875_+|cation-diffusion-facilitator-family-transporter
MTIQKGLHERRALKISIAVTFLLAVVGILFGLLSGSLAIVFDGMFNMVDTVISILAFFVARLLTSKGNRRFQYGYWHIEPMVLVLNGSILILLCTYALVNAIGSLMSGGHELNFDWAFVFALLVFFLSTGMYFYLVKTNRKIKSEFLRLDIQSWLMSALISTSLLLAFGIAALLHGGAYGYFTPYIDPLILAILTAFLIFVPMAAVRDAMRDIFRMAPVDLDERIREFLDELIKQHDFKTYTSYVAKIGRAQFIEIHIVVPMDYPISSIETLDKIRNEIALAIGENTPQRWLTIAFTANENWI
>NC_006368.1|WP_015961263.1|2307400_2308807_+|ATP-dependent-RNA-helicase-DbpA
MIQSEHNDQHLSFSQFPLRQELIKSLASSNYENMTPIQMQSLPIILRNEDIIAQAKTGSGKTAAFALCLLNNLKISFFAVQALVLCPTRELAEQVSQAIRRLACLMPNVKIINLSGGIPMQPQLDSLRHGAHIIVGTPGRILKHLKNASLDLSQVKALVLDEADRMLDMGFFDDIKNIISVCPKQRQTLLFSATYPEEIKRLSKQFMKDPKEVHVVTPPEEIDIEQHFYEVSRHAQKFPLLKSLLLHYRPVSVLIFCNTKQQTVEVTDQLINEGFSAIALNGDMEQVERDLAVLRFANQSCSILVATDVAARGLDIKELSAVINFDLAFDHDVHIHRIGRTGRAGSKGIALSIVTPADAQRICAIEDNYPHPIHWGNINALENHNTACLVPEMVTLCIASGKKDKIRPGDILGALTKDAGLAGNTIGKINITAMYSYVAIHHSQADKAYQYLQSGKLKGRKVNVRKIN
>NC_006368.1|WP_010947832.1|2306951_2307161_+|cold-shock-protein
MSKTVNGVVKWFNEIKGFGFIEQEGGPDVFAHFKEISSSGFKTLTEGQRVQFIVTQGAKGLQAQNITAL
>NC_006368.1|WP_015961262.1|2305901_2306213_+|hypothetical-protein
MKKINVLLYLLTMLTISFATISHGASEDTDTTNPTKYIYRGSSITLEELATVADLSTARDQKGNPVTLEEESYQIGSFTRGTVTIIPKSGQADDVITLDLKPN
>NC_006368.1|WP_031285541.1|2303824_2305582_-|alpha/beta-fold-hydrolase
MKGLEKQCCSKERILTQSQELQEGGDFSCCVPVESTSSNSFFSFFTRLTQANLAKWTAGISPAAIGSSYSTWLWQLAQSPGVLWELAFYPVLHAKDCINNIVCAERAADGKDVRFKKNSWQPMPWRLFAEGFLQMEDWWRRATTDVPGLPKPVERTVSFWARQCLDALSPSNFAWSNPDLFHEAMRTGGLNLIQGTQIALEDWLEKLAGAPPTGSEHFIPGQHVAITPGRVVFQNHLIELIQYESHTKTVYKEPILIFPAWIMKYYILDLSPHNSMVKWLVSQGHTVFIISWRNPDKEDRDLGMDDYYRQGAMAAIDTVSTLLPGTKINLMGYCLGGTLAMITASAMGRDKDERLNSLTLLAAQGDFTEAGELMLFVTESQVDFLKSMMREQGYLDTKQMAGSFQMLRAYDLIWSKMVQDYMHGMRRGMIDLTAWNADATRMPYKMHSEYLEKLFLRNDFAEGRYTVEGKPVAAENIERPVFAVSTEKDHVAPWQSVYKIHLMVKGDVTFVLTDGGHNAGIISEPGHLGRSYHVHEHTQGETYLNPESWLAMANVREGSWWQEWHEWLVRQNSKKLIPPPGLYPN
>NC_006368.1|WP_011213396.1|2302583_2303759_-|ISL3-like-element-ISLpn11-family-transposase
MPKKDCILNLPGYSIKKVSGENPVYIEVSYRRVVRCIHCGNKKLRKKDSFIRRIRHESIGLRRSYLCIKAHKYYCPACGRYFNQRFPGIGKYQRASESLRKQVFHYHSKGVSQKDLARDLKLGKSTVERWYHYGYELRYKKIATRSCPRVLGLDEHSFNRKVGYATTFCDLAKHKIFDVVEGRSEKDLEGYLNTLEGKDKVQVVCIDLSSSYRKLIRRYFPNAMIVADRFHVIRLLNQFCLQTYQQIDPEMKYQRGLLAALRTNPNNLTVKRLNRRERYLQQQPVIAAIYYFKQRLHRLLMRKHRTAKQCTRLIPLFLKLVASLKESPFDSLKTLGKTLYQWREEVVRMWRFTKNNGITEGFHRKMKLIQRRAYGFRNFENYRLRVKVLCS
>NC_006368.1|WP_021437119.1|2317323_2317587_-|transposase
MMMSFAGEGWGEGMSRMVIDDEMWSRLEELLPKPKGRHDKNERLSMEAICTMLCAGATWCDLPPYHGNWKSVYNRYNNWSKKGYITT
>NC_006368.1|WP_010946556.1|2317758_2318052_-|GIY-YIG-nuclease-family-protein
MQVKQPAIYIMANKRNGTIYTGVTSDLIKRVYEHKYGDVPGFTQEHGCKFLVYYELIEDMISAIAREKQLKGGSRKKKLALIEKLNPYWEDLYEKLL
>NC_006368.1|WP_015961270.1|2318077_2318863_-|transposase
MSITELADILNGYFSWNKSRIECFATILISLIKVRTVNLTEIACGFSSPAKQDSRYTRIKRFFREFKIDFSSVSAWVILRIKNNVITTNSRGLEVSIDALFYDLKSGEQRILQGLRKLWRQKIYLSALRLADGELLIVATDHLMDEPIEHYALRWEIETLFSCLKGRGFNFEDTHMTQPDRIEKLLVLLTIAFCWAHKTEEWRHVQKAIKIKKHGRKGVSFFRYGLDLLRDAALNGCQFIHHSFSDILGFLCISRVICAAE
>NC_006368.1|WP_015961271.1|2319044_2319797_-|hypothetical-protein
MFSKILKSRPNFFKAISEICNPGIGDKILKLQKPSLLIRIDGRSPDSLHIQDGFQPRVSGERLKSVTASDVEDYQKFNVNPFGWGACQSLKEIMTFMQKNKSQTDKGWLYKFFGKATPLLILKQEVGADSHGHDDEKEVIITEHIPLKNFIASIAPEDREMFMDGREIPNAMYSYNSSLPKSLSKQDLLTEQDILAWLLRHDAEEPFTDLCQTVFTDMPQDILEYLFQENTGIVSAITSAIEKNMVLNLL
>NC_006368.1|WP_011946965.1|2320235_2322056_+|NADAR-family-protein
MIVIPHEVFVSKPNTALISMRYIVTTGNDYTLESEIMNVKPNIQTTLQNGKPLPYQKIGNQKVASFKDPNKPPYGPFANTTNAGEFPLKQTVLIHGIEYSFTWPSSEHAFHAQKLIHLMNKLGINDPNQIHILNTLRKIEKTQNQAGKQFDPRENWDPIARELATNMGITGTDQDKKDKIDELCDSNYYSKALVKKGIVPGTKEPYTRRFMATVLRLKCDQNPELKELAMRCASEGILPIEASTKDVNWASGIDGSGRNMLGIEILKLGNQYLMEAGRGNEIKIADPDKAYEDLQRSHQKDLGHDAIIGKPWSNPLNNSLNIWYDSTRKQTVVESHRGSNLQLIYKDGEPPKAIWRKDENSPWQDGDFKRPAVQSLLQAYQDAGSPVPTVAKQQPHPAQLNDRWAKVHKQHHDNPVINLPLFKQELREGVKLELNKIEAELKKGINPLFSRNESHLERIVREYVNPAVLEASKILAAYSVKNAMHDLNTSVTVSMVDNNRAHDDKHPLHAMKIQFKDNAEAKQFAEKLLNEYGIHSHTFGKGIMKTPQNGAIYLTPKDLQMLSQLSGLAKDPLAGLQAFANMAKNYDKAKEVSIKEDLESHAGLSP
>NC_006368.1|WP_013101666.1|2322299_2322590_-|GIY-YIG-nuclease-family-protein
MHPSYVYILASQRNGTLYIGSTSDIINRVWEHKNKVIPGFTAKYNVHMLVYYEMYDLYIDAARREKRFKNWPRQWKINLIEKFNPEWRDLYEEICQ
>NC_006368.1|WP_015961274.1|2323928_2325671_+|ankyrin-repeat-domain-containing-protein
MSFSKISKTLENSATLIDEKAEQDASDLSHTLGSDSQLLISEESSDVLLENTGENLVQQACIDGNLEKLKELLRGDMWGMDEVSLNQVNNRGETLLMLAIKYGHKQMALFLARSLFHLHKIDNSGKSALSLAHEKGWEDIVQLILESINNREARIRELHYAAIHGYVESVSQLLGIIDKYGFKPHGFILVGDETPRFENIFHAACCGGSLEIVKLLIEHGADINSKSQFSENNYSHYPATPILVACRYGHANIVEYLLAQDGIEYDINELLHTAVGFGHFAVLDLLLRHSKENSTRNLNIVGEYPLTHFSATLLTRACYSGQVDIVDRLIAEDIDMSNADNRQAFWTAIFCAKTQGSPAIDIIDRLLAENDRQNIDIPLDGFKDLVLWAYRQPFVGILDRLIIRGVDFYRERDPGDYPLIEAAKNGYKDIVHRLIDLSVDINLRDRKGRTALFCAVMQGEKEIVELLINNGADPNIQDNEGVTPLMKVVPTDNSEMVEFLLNAGADTSIKDKRNRLAIDLAKHFPYHMKLLKDATEIQNANKSSSSSNQSANALYTLWYSNRGDLREEAQFKEKNTPHPF
>NC_006368.1|WP_015961275.1|2326168_2327248_+|hypothetical-protein
MNALSLIRQMAEKPELNEFIQGIKEGNLTAEHVKLFCQATAQVGVEATRGLWDTNVEQNDFSNDKNREAIYSASLLHGAHNIGHVNNLLHNKNIGISDRSKEAIIGQMEDHSPIGSRRDLAWEKEIATGFLHDAINKFQEGRAKNAAKKGSGDKDFHDGVVDMVGFVMHSLFGVGKAMGRGFLDSQERFSNSAQSNEPTINEHGQLINERLASTPQEPYVQNIGSSKSSIGVSPQLNSTTQNSTIPNEIRKFVTGGLQFKNDDQQVVDNTIEDLKTEVISAFELHNMVQDLPTSKSVQGIEAFKVEQEPSRSNDVTHYFKSILQQLKTTDPQPHKGEIAAHNPGEDNESDISKSIRFRS
>NC_006368.1|WP_015961276.1|2327546_2328452_+|LysR-family-transcriptional-regulator
MHMSDIKSFLAVVEFHSISLASKRMHISQPTMTRRIQKIEQELGTPLFFSSGIRTELTAKGKELLPYFRQMLDIYQQMYINVGNKTKNPLKLINVGTSVYVANSIIQDFMHSAEISSSNYFFNIKLLAEPHIIDSLNSGEYDLIIAPPVYDCSSSVVSIPLWKEKILAVVGASHPLARNKKAISITELMSHDVALMEKGFTLRKKLDSLSEGLHTPLKAIFESNSIYNNIALIEKGVGWCLIHERLLNPNLIPVELSDCNMEIEFHCSFLKRREDERLIWQFLEQIRKWILADYLKQYACP
>NC_006368.1|WP_015961277.1|2328666_2330421_-|ankyrin-repeat-domain-containing-protein
MSFSKVNKILDSNSILKEEIDKPEVLGLAQSSGGEEPPMIPDEMLFALQDRVGVNRVQQACIDGNLHVLERMNCDEFDYVDSYGTTPLMLAIEHDHKAIAYYLLRSRMINLNLHKKDNAGRSALSMAKEKGWDDIVDLIRNTMENPVYNNMELYYATINGYLDSVTELLPKIDEPGFATKETWINTYPLFGNIFHAACCGGNLEIVKLLMEYGAEINSRSYNRERHNFYYATTPILVACRYGHAHLVEYLLTQDGVQYDIIELFHIAVEYGHYAVMDLLLRKIRAENIALDLNRGLEFHASWYGTPLDKACRSGQVDIVDRLIAEGIDMKEEDNISAITTAIWNADNPEYPAIDILDRLLAECDRQGISIPLTAPEIAIIACNRNRADILDRLIIRGFDFNLGNRHGEYPLITAAIKGHEAIVDRLLSLSVDVNQRDSEGKTALFQAARHNNLEIVKLLVNNGADINIPDNKGVTPLMRVAETCFTEVVKYLLNSGADTSLKDKGGRSALDYASSSSLYFMQENLALIRDADIQKNLYKSPSSSSQSVNNPYMLWSSNRANLPEEESVKSEIISEEKAFTFQSK

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Crispr_ID: NC_006368_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006368_3

3077948-3078442

Orphan

Consensus_repeat	Method
CAGGGATTACCAGGCCCTAAAGGAGAC	CRT

10 spacers

The CRISPR arrays of NC_006368_3

>merge|NC_006368|3|3077948-3078442|CRT
CAGGGATTACCAGGCCCTAAAGGAGACCGAGGAGAGGCAGGGCCTCAGGGATTACCCGGACCGAAAGGAGACCAAGGGGAAGCAGGACCTCAGGGATTACCAGGCCCGAAAGGAGACCAAGGGGAGGCAGGGCCGCAGGGATTACCAGGCCCTAAAGGAGACCGAGGAGAGGCAGGACCTCAGGGATTACCAGGCCCGAAAGGAGACCAAGGGGAGGCAGGGCCGCAGGGATTACCCGGCCCTAAAGGAGACCGAGGGGAAGCAGGACCGCAGGGATTACCAGGCCCTAAAGGAGACCGAGGGGAAGCAGGACCTCAGGGATTACCAGGCCCTAAAGGAGACAAAGGAGAAACGGGAGCAGTAGGTCCACAAGGTATGCCAGGCCCTAAAGGAGACCAAGGGGAAGCAGGACCTCAGGGATTACCAGGCCCTAAAGGAGACAAAGGAGAAACGGGAGCAGTAGGTCCACAAGGTATGCCAGGACCTAAAGGCGAA

>NC_006368|3|2|3077948-3078442|CRT
CAGGGATTACCAGGCCCTAAAGGAGAC	CGAGGAGAGGCAGGGCCT
CAGGGATTACCCGGACCGAAAGGAGAC	CAAGGGGAAGCAGGACCT
CAGGGATTACCAGGCCCGAAAGGAGAC	CAAGGGGAGGCAGGGCCG
CAGGGATTACCAGGCCCTAAAGGAGAC	CGAGGAGAGGCAGGACCT
CAGGGATTACCAGGCCCGAAAGGAGAC	CAAGGGGAGGCAGGGCCG
CAGGGATTACCCGGCCCTAAAGGAGAC	CGAGGGGAAGCAGGACCG
CAGGGATTACCAGGCCCTAAAGGAGAC	CGAGGGGAAGCAGGACCT
CAGGGATTACCAGGCCCTAAAGGAGAC	AAAGGAGAAACGGGAGCAGTAGGTCCA
CAAGGTATGCCAGGCCCTAAAGGAGAC	CAAGGGGAAGCAGGACCT
CAGGGATTACCAGGCCCTAAAGGAGAC	AAAGGAGAAACGGGAGCAGTAGGTCCA
CAAGGTATGCCAGGACCTAAAGGCGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_006368.1\|WP_015961720.1\|3069092_3072695_-\|SEL1-like-repeat-protein	unknown	unknown	gnl\|CDD\|276807
NC_006368.1\|WP_015961728.1\|3082864_3083962_+\|competence/damage-inducible-protein-A	unknown	unknown	gnl\|CDD\|238450
NC_006368.1\|WP_015961726.1\|3078954_3080811_-\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NC_006368.1\|WP_015961717.1\|3062115_3063480_-\|leucyl-aminopeptidase-family-protein	unknown	unknown	gnl\|CDD\|238247
NC_006368.1\|WP_013101905.1\|3065740_3066952_-\|lpg2637-family-Dot/Icm-T4SS-effector	unknown	unknown	unknown
NC_006368.1\|WP_010948351.1\|3085450_3085762_-\|50S-ribosomal-protein-L21	unknown	unknown	gnl\|CDD\|235510
NC_006368.1\|WP_015961724.1\|3076955_3077615_+\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_015961727.1\|3081606_3082425_-\|phenylalanine-4-monooxygenase	unknown	unknown	gnl\|CDD\|237020
NC_006368.1\|WP_015961731.1\|3087368_3088460_+\|redox-regulated-ATPase-YchF	unknown	unknown	gnl\|CDD\|236583
NC_006368.1\|WP_015961730.1\|3086780_3087350_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|235457
NC_006368.1\|WP_015961729.1\|3083920_3084946_-\|GTPase-ObgE	unknown	unknown	gnl\|CDD\|237047
NC_006368.1\|WP_015961719.1\|3067303_3068686_-\|Dot/Icm-T4SS-effector-MavV	unknown	unknown	unknown
NC_006368.1\|WP_010948350.1\|3085159_3085438_-\|50S-ribosomal-protein-L27	unknown	unknown	gnl\|CDD\|235464
NC_006368.1\|WP_015961718.1\|3063484_3065056_-\|murein-biosynthesis-integral-membrane-protein-MurJ	unknown	unknown	gnl\|CDD\|240528
NC_006368.1\|WP_015961723.1\|3074179_3076687_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|227334
NC_006368.1\|WP_010948352.1\|3086004_3086664_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	unknown	unknown	gnl\|CDD\|235534
NC_006368.1\|WP_015961722.1\|3073284_3074007_-\|L,D-transpeptidase	unknown	unknown	gnl\|CDD\|341130
NC_006368.1\|WP_011947563.1\|3080822_3081482_-\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|236538
NC_006368.1\|WP_015961721.1\|3072721_3073288_-\|hypothetical-protein	unknown	unknown	unknown
NC_006368.1\|WP_010948336.1\|3065413_3065680_+\|30S-ribosomal-protein-S20	unknown	unknown	gnl\|CDD\|178943

Protein	Function_ID	Function_description	E-value
NC_006368.1\|WP_015961728.1\|3082864_3083962_+\|competence/damage-inducible-protein-A	gnl\|CDD\|238450	cd00885, cinA, Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of proteins involved in biosynthesis of molybdopterin cofactor, where the domain is presumed to bind molybdopterin.	8.00124e-65
NC_006368.1\|WP_015961718.1\|3063484_3065056_-\|murein-biosynthesis-integral-membrane-protein-MurJ	gnl\|CDD\|240528	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	4.54131e-157
NC_006368.1\|WP_015961717.1\|3062115_3063480_-\|leucyl-aminopeptidase-family-protein	gnl\|CDD\|238247	cd00433, Peptidase_M17, Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and play a key role in protein degradation and in the metabolism of biologically active peptides. They do not contain HEXXH motif (which is used as one of the signature patterns to group the peptidase families) in the metal-binding site. The two associated zinc ions and the active site are entirely enclosed within the C-terminal catalytic domain in leucine aminopeptidase. The enzyme is a hexamer, with the catalytic domains clustered around the three-fold axis, and the two trimers related to one another by a two-fold rotation. The N-terminal domain is structurally similar to the ADP-ribose binding Macro domain. This family includes proteins from bacteria, archaea, animals and plants.	2.81107e-179
NC_006368.1\|WP_010948351.1\|3085450_3085762_-\|50S-ribosomal-protein-L21	gnl\|CDD\|235510	PRK05573, rplU, 50S ribosomal protein L21; Validated.	3.12311e-48
NC_006368.1\|WP_015961727.1\|3081606_3082425_-\|phenylalanine-4-monooxygenase	gnl\|CDD\|237020	PRK11913, phhA, phenylalanine 4-monooxygenase; Reviewed.	1.94098e-137
NC_006368.1\|WP_015961731.1\|3087368_3088460_+\|redox-regulated-ATPase-YchF	gnl\|CDD\|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
NC_006368.1\|WP_015961730.1\|3086780_3087350_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	6.13567e-95
NC_006368.1\|WP_010948350.1\|3085159_3085438_-\|50S-ribosomal-protein-L27	gnl\|CDD\|235464	PRK05435, rpmA, 50S ribosomal protein L27; Validated.	1.71023e-54
NC_006368.1\|WP_015961729.1\|3083920_3084946_-\|GTPase-ObgE	gnl\|CDD\|237047	PRK12298, obgE, GTPase CgtA; Reviewed.	0
NC_006368.1\|WP_015961726.1\|3078954_3080811_-\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NC_006368.1\|WP_015961720.1\|3069092_3072695_-\|SEL1-like-repeat-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	9.92743e-35
NC_006368.1\|WP_010948352.1\|3086004_3086664_+\|50S-ribosomal-protein-L25/general-stress-protein-Ctc	gnl\|CDD\|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	1.91152e-78
NC_006368.1\|WP_015961722.1\|3073284_3074007_-\|L,D-transpeptidase	gnl\|CDD\|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	6.34136e-17
NC_006368.1\|WP_011947563.1\|3080822_3081482_-\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	gnl\|CDD\|236538	PRK09483, PRK09483, response regulator; Provisional.	4.21616e-95
NC_006368.1\|WP_010948336.1\|3065413_3065680_+\|30S-ribosomal-protein-S20	gnl\|CDD\|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	3.56537e-27
NC_006368.1\|WP_015961723.1\|3074179_3076687_+\|EAL-domain-containing-protein	gnl\|CDD\|227334	COG5001, COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms].	6.64908e-82

>NC_006368.1|WP_015961724.1|3076955_3077615_+|hypothetical-protein
MPFCFSNQPNILNNKLILKILVLILFFSNSSLAKTINYPWTVSASLGYVNYQYVHEGDHITATGRFAIGRDLLMKGPFLFGLELGLQSGNQMRLQMTEEEVDALGGLLVQTTLKPMVDALATIRITSEFTAPLFLQLKAGTAYRQWQMDRDTINDISQLAGEIMAGCGYTITPNASITLSYQGLFGDKPNFTIDLESGIGHVQKIPVQHAILLGIVLMI
>NC_006368.1|WP_015961723.1|3074179_3076687_+|EAL-domain-containing-protein
MSPLKSKIKTKSFNKLTKTQDITNTIERLFANSQDSIIVFNQQGKIIAINEKAAALFKKSPDKLIDKPIWKLFKLNSFAIKRQFIQAKRCFLLANEGIAQQFTWLESKAQKPVLAYHILFNKTEIEDTSIIFTKLTDILKSKTIEWILWSLTKISNHQEINEIIDQILQLTSDVFAADYTSVSFINNQQIARTISYYKFGKKEENISFSLINTPCAKVIQKKAICYFNDVQKQFPNDKLLKKMKINTYLAGPITNPQDEVIGIMTILCKREVEFDTLNKTWFGLFLSRINSEIERLINLRKLEFLASIPQQNPNPIIRILLNGDVVFTNDEGKIILNYWIKLFKGLPVELLKEAQRIQKSNQNTRIEMEIEDKIYLFTLVWIDEFKQINIYGTDITQLKNTQNAMLNLTRRDTLTQIANRQYFEEKLIEKIYEHHLKEKSLALLLIDLDNFKIVNDTLGHPTGDKLLMAVTNRMTRCLRANDFIARLGGDEFIVLLDQCNTDTAVKVAEKIINVLDKPFQFDDYHMTITASIGIAIYPETSEIARDLLKYADIAMYQSKKTGKNKCTVFSKNLHYKENQRNEILKKDIELAALKRELYIDYQPQIDLSDNTIVGIEALLRWSHPTLGLILPTEFIPIAEQTGCIHIISQWFIEQTLLDYSQFQQLNSNIKLSINVSLSQLNDMRFTKILCDSLLQNNLSKSKIILDISERMIAPHFIQISKKLKQIHHIGINISLDNFCCPQISLPELLSLPLDYLKVDQRLLIGIEGKIKLRKLLSGIINLTKDLNIKIIQKGIETAEQHEVIKSLGCQYAQGYFYCKPVALNDLLPLIKKTIH
>NC_006368.1|WP_015961722.1|3073284_3074007_-|L,D-transpeptidase
MKKILLTTFMMSMVTVLNAGHFYGTALCAYPQYECIKVTGGQSWEKLFPDPVQRDIVQRVNRTYNYLWSGREIAVPKNLANINIFDVSPFPLKIQSENEKQIIVDQEKLAWGAYDAQGNLVWWGPISSGSDKCSDSNKVCRTLTGIFRVFSKENVRCTSDVFPIGRGGAKMPYCMYFHKGFALHGSDDIPGVRASHGCVRMFIQDAKWLNENFVELSSERNNFMGTKVIVRPLNDSENKK
>NC_006368.1|WP_015961721.1|3072721_3073288_-|hypothetical-protein
MNLKSRSSITAIVVILLTSALNISVFAAKSNKAATAEDKAEKKDNGKFPLGCTAVGYQQNLKVLTLLPGKEGALQSMYFIYNTLPETVSLYQMHDKESLYSYWLNHSIRGNSWAVLATGEKEVKFICTLGDGKKSYGKILDCADVIKVCEYVNVKFGLNNKGNFWIVDSNTRNGAVSQVVHYGIIPGV
>NC_006368.1|WP_015961720.1|3069092_3072695_-|SEL1-like-repeat-protein
MKSLVPWVCVLVASAGQQAFANDAFNAYRLGNYNEAAEPLIIKSGQDAVAEYYLGRLYLYGYGQLKNNRVAMRYFTKSAEKGYLPAVLLMAKYSLLHEKNPEEAARWFKQAAAVGDVSAQMFMAAAYLYGVGVKKNTDIARRYYIDAAKNGNPIAQYTLAEYFLESKHAGNKKLGIIWLNKAAENGDPKALTELGRFYVAGQMVAKDTSKGVELLNKAASEQYAPAMLELGKLALMQNQYDEAIQWLNKAAKQSTEATLELAHIYLQDKSPVYDPKTGFLLVLKAAQNGSVQAQKELANLYQKGIGVAADEELSKQWTLKAAENEKKNAEPPVLAQAALWLSNDRTDKLEETAYQMNGIFSPWNNPSALRNNSYNQAPKLETISRQDIFKPQFELTQPNNIPISNYYDALISKQVEFQSNQWAYPTYRLNPFVEALERANSPVVQKLNLPVPYADANYDDSEVGSFDLMDIWTGDWKRTVNYMSVVNYLYFRAILGNAQTQFEIGQLFQYGIGLMQDDASAIIFYENAAEQKHLGAEYNLGILYLKRGKDENDYQQALNWLTDSAFKGNKRAQYVLARILRQGIVGPDGKEYIKANDEQAMAMLYLSAANDYGPAEYELAEYLARDYNNGLSVDVRKQKIALIRKLYQGAVKNKVAEALLPLAFYNAMDDNRQKQEQAFKVAEEQAETGNENAALLLGMLYDRGIGITADPAKAMYWYQQAGQNPVSQFILGTYITEGKGVAQDKEKGLDLLKQSADSQFSYADFNLAVLKQQSGEDFLPNLIESYKLGNSHAGIVLADYYLSQSSVPEQMNQAKEIYQGLADKGDQYAQLKLAYMLQKGLGAAPDLAGAQHWYTASAEQGNPEAQYLLGQFYQLGETGEPDYNLAKHWYQKAAKHLSKADVALGFIYETVDDNYAQALKAYENAAAKGDMLGAYNLALMYEYGKGVPVNYSKALSLFKEASEKGAPEAMSQLAGMYFYGLGQPRNEQQALVWYKKAASLGNGNALYALGLLSETGVGVKLDFPDALRYYQDASDKGNEKAMLALARMYHYGLGVEKDHKRSASIYQKLAQKQNAYAQYQLGTYYIEGTAGERLPEKGRELLQQASENGSLQARRVLQRLDAQTQGKVSYVEPVLFNNVPKFDGQSADMIYFDALNEWNHGEEVLSRMILQRLVTQYPNFIPAKRAYEQLNQAKLMNNLG
>NC_006368.1|WP_015961719.1|3067303_3068686_-|Dot/Icm-T4SS-effector-MavV
MKYAVTFCTTDQEVGSNPLWHSCLLLSKMDETSKLLEVVDNWGFYGLPTTNRNNSWLDQLKIKMGLDVDLIGNHGMLRHEELRFLDQGCGLRGVTFELTKDDFELLQKKCLQMATDQETAINEFVETQGIKGKPPEKTRIYPHEQFSRLIYATENIKAEQQGREARLKPFELRLSWGLFGPSLALSQNCKTQALSLLSYVLSKEQIERLTEYGEHPTVPRRSGPMESIFLHSTGPLREHRKSSGDVVHYRDLKDPGVKLYWTVPPQELEALSEETIKLLQIDGEYCEEVKAIVRKLQRLEWLLINSNLPEKYRPYKDELINKVVGCYKAFSFIEPKQEEPKLGGWYGWALSLFSAPRSAEERTLQGKIKKAKSLFNSIYMAIVDNYQIDDNAPMENENILPYEETGENRFENMVEAVASYLSRKDKINLCKIIGRTYCEDHVELEDNEGKIALSPQPLAT
>NC_006368.1|WP_013101905.1|3065740_3066952_-|lpg2637-family-Dot/Icm-T4SS-effector
MFLTINDLQSQIQLAKKRLYVLAKNWLDTQKEAINSKDKANWLNAFQASTKEAMQEQLKATGFPLIRNAILVNQSEGELPQHSLEQSSSLIHSENFPEQFNSRTVPRVIYVCHSGENNQVIKRLGQLTTLMEQLHTLEELTFEVQTNVHFRGLNLAYRMARSINKEWRDVEKGRETVEYYAERLQIAEKQYKLASDFCHECLGIYKEQLDARIMYFNESLNFFVECLAAAFSSVKDDRYWLTKFLLPSLPWHSMLNEVATWLFTTNGFTNPTIDSIEVNRSHLKAITEQFAKLMMAPFCSLEKELQGKIEKVENEQKIARENVYAMSSELDIVIHMQSQRKLAALLFPAQPLSMLGFFQGVAAAMGRDYFYSTFIKGNQSQEPRITDDEKPLIEASNYSNGLH
>NC_006368.1|WP_010948336.1|3065413_3065680_+|30S-ribosomal-protein-S20
MANIKSAIKRARQNVKLRQHNASARSMYRTYIKNVLKAVESGDQEAARAAYTKAQPVIDKAANKGLIHKNKAARIKGRLVARLKAMAA
>NC_006368.1|WP_015961718.1|3063484_3065056_-|murein-biosynthesis-integral-membrane-protein-MurJ
MLTTDIMVPKKQSLIRSTSLVSLMTFISRIVGFARDMVLANFFGAQAGMDAFFVAFRIPNFMRRLFAEGAFSQAFVPVLAEYQKTRSAEDVRTFIARISGYLSSILTLVTVVGIVASPVIIFLFAPGFHHDSVRAELATQMLRITFPYLMLISLTAMAGAILNTYGYFGVPAFTPVLLNISMILAAVYLCPNLPQPVVGLAWGVLIAGIVQLLFQLPFLYQRHLLIRPRVVRDDPGVNKVLKLMIPALFGVSIAQLNLMIDSIFASFLKVGSVSWLYYTDRLTDFPLGVFGVAIATVILPHLSRKHTEQNINQYSRALDWGLRSILLIGIPAGLGLSFFALPLIASCFAYGKFTAYDLLQTQKSLITLAMGVPAFMVVKVLASGFYARQDISTPVKVGAIAMVVNTLLCFVFVWHLAHAGLTLASALAGYVNCVILLFLLIKRRLFKPSPGWLKYSMQLLIANFTIGVYLYFMSGTATYWLGFSPLMRLSLLLAHVFVTVVIYLLVLGIIGLRPSHFRGQIKD
>NC_006368.1|WP_015961717.1|3062115_3063480_-|leucyl-aminopeptidase-family-protein
MQAEVFYKSCGDRIVPVHLISQSQWDEGIENLTPMERNCFSVRQFKGKLGDYCFILNADGVIEKAFIGSGTGNQESALANAALLLPPGNYQFQDKLSRESGVVWGLAQYRFDEYKKYELQPRVLIVEANDMDYILSLANSLFLVRDLINTPTCDMGPESLAHVVEELAKTHKAYFKQWIGEELIKDNFPAIHAVGRASALAPRLLSLHWGNEKHPRVTLIGKGVCFDSGGLDIKPSSGMRLMKKDMGGAAHVIGLAQWIMVQRLPIRLQVLIPAVENAIGPNAFRPGDVLTMRNGLTVEIENTDAEGRLILADALVKACEEKPDLIIDFATLTGAARVAVGTEIAAMFSNHDELAQDIVSASNKVSDPVWRLPLFSPYEELLNSNIADMSNSSSSSYAGAITAGLFLQRFVAKSIPWVHFDIMAWNTVSKPGKPEGGEAMGLRAVAEYLLQTYG
>NC_006368.1|WP_015961726.1|3078954_3080811_-|excinuclease-ABC-subunit-UvrC
MNDLQLSAELALFLTKLPSEPGIYRMLDEEGTVLYVGKAANLKKRVNSYFSKQNTGVKTRALVSQIKSIEISVTRSETEALLLESNLIKALRPKYNVLLRDDKSYPYIHLSNHPDFPRIELYRSKKKPPSGNFFGPYPGVAAVRETIVTIQKIFKIRNCRDSYFKARSRPCLQYQIKRCTAPCVHYISPENYKLSVEDAIRFLQGKCQIILDALAERMKQAVNQLNFEEAAVLRDQIKNLRLIQEQQGVVQLRGDADVIAIEVRPGFACIQCVTIREGQVLNSQSFFPTVPYAVLDEELDANSLWQQTFEAFIGFYYLDTTERIPDLIITNQSITESRSLEYILSQRRGKSCKIQVNPRGVKSRWMDFAVNNLRISVAEYVSKHSTIRSRYQALKQLLALDKNIERMECFDISHTQGEATVASCVVFDTEGPRPSEYRRFNIEGITPGDDYAAMEQAVTRRFKRLIDAQLLPDVLIIDGGKGQVSIVKRVLTSLGVEDITLLGVSKGPSRKAGWEKLILVNENREFVLPEDSKALHLLQHIRDEAHRFAITAHRKKRQKTRVESTLESIEGVGAKRRQALLQRFGGLRELAKAPLEEICKVQGISEQLAKRIHEHFHP
>NC_006368.1|WP_011947563.1|3080822_3081482_-|UvrY/SirA/GacA-family-response-regulator-transcription-factor
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIAVTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQEPQDSPFDLLSEREMQVMLMITSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD
>NC_006368.1|WP_015961727.1|3081606_3082425_-|phenylalanine-4-monooxygenase
MEFSSRYVAHVPDAQGLVDYSAQENRIWNILFERQLKLLPGRACDEFLSGLQTLGLNSSTIPQLPEVSERLKAKTGWQVAPVAALISAREFFELLAEKYFPAATFIRSEEELDYVQEPDIFHELFGHCPMLTDRVYAEFVHDYACKVLTFPEQDWPLLQRMFWFTVEFGLIKTPKGLRAYGGGILSSISETVYCVESDIPVRILFDPVVAFRMPYRIDQLQPVYFVIDSYQNLYDFVLSDMGKFMDRARELGEFPPYFDVDPENPNIHIRAC
>NC_006368.1|WP_015961728.1|3082864_3083962_+|competence/damage-inducible-protein-A
MTIAILSTGDEIIHGDTLNTNAHYIAHALCSEGLPLGLQVACSDKENEIIDSLNFLTEHHDILILIGGLGPTKDDITRFALAKFTKEPLIQHADALAHIEKKANIAKISLNQGNLQQCLFPANARLFPNPYGTAMGCSYSWKGKVFILLPGPPRECLPMFNQDVLPLLLQTSRHSNKQILRWRVFGLAESEIAQILEEALEGLDCQTGYRLETPYLEFKVRCKRELIEKITSIIDPILAPHIISSLETKASDQLRSLILKNNEPITIIDEITGGLLQSLLVRPENYHLLNFHNLNRTKLYFHCSGLEDYWSQQAPQGTTKLIINYSNQMQEGRETHQIPYRSAMVVHYAAEWLSFRLFHLINQLH
>NC_006368.1|WP_015961729.1|3083920_3084946_-|GTPase-ObgE
MKFVDEALIKVEAGKGGNGCLSFRREKFIPRGGPDGGDGGDGGSIYFEASSDLNTLIDFRYTRQYKAENGQSGMGGNCTGKKGEDLTIKVPVGTMVYDADTGELLADISQPGVPVLIAQGGFHGLGNTRYKSSVNRSPRQTTPGSPGESRNLRLELRVLADVGLLGLPNAGKSTLIRAVSSSKAKVADYPFTTLHPGLGVVRVSPYKSFVMADIPGLIEGAAQGAGLGHRFLKHLSRTCVLLHVIDIAPLDGSDPVADAKAILNELTQYNPDLLNKPRWLVLNKIDMLPDEKEREEKIQSIIKGLKWKDKVFSISAIESKGTQELCYALMQLIDEMKESEA
>NC_006368.1|WP_010948350.1|3085159_3085438_-|50S-ribosomal-protein-L27
MAHKKAGGSTRNGRDSNPKYLGVKRFGGQFVNAGEIIVRQRGTRFHPGPGVGCGRDHTLYALVEGLVQFTTKGEKNRKYVTILPEQREEAAS
>NC_006368.1|WP_010948351.1|3085450_3085762_-|50S-ribosomal-protein-L21
MYAVIKTGGKQYTVKEGDVLKIEMLPENVGNEIKFSEVLMLVDGDKVTCGTPFVAKATVKAEVLDHGRHKKVKIIKFRRRKHHMKQMGHRQYYSQVKITAIGK
>NC_006368.1|WP_010948352.1|3086004_3086664_+|50S-ribosomal-protein-L25/general-stress-protein-Ctc
MSTIQLEAQSRTDMGKGASRRLRRLENKVPAVIYGGSKKPMAIHFSHNKVIKALETESIYSSVFDITVDGKVEHVILKALQRHPYKPIVLHMDLQRVSSKDILVKLVPVHFINEEQSPGIKAGGIVQHTMTQVEIRCQAKDLPEFIEVDMSKVGMDDVVHLSDLKLPKGVQLTVDVADGSHDAPVVSIHAAKVSSTELEETPEVPASAVPTTDQGESAE
>NC_006368.1|WP_015961730.1|3086780_3087350_+|aminoacyl-tRNA-hydrolase
MAIKLIVGLRNPGSAYEQTRHNAGAWLVTALAQRHNSHFKIDKKMQAELTEIDINNHPCRLALPLTFMNHSGQTTRIISQFYKIEPGEILIVHDELDLPVGRIKLKTGGGHGGHNGLRDITAQLGTGEFHRLRIGIGHPGHKDLVHQYVLSRPSMHDRQQIYDAIDRGIAIIPIVLSGDMARAMNQVNA
>NC_006368.1|WP_015961731.1|3087368_3088460_+|redox-regulated-ATPase-YchF
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSNIVKPQQVVHATMQFVDIAGLVKGASSGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVDPLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIFELKTLEKIKAHLDAGYPVRTLELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVQALASQENASIVALCAATEAELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGATAPQAAGVIHTDFEKGFIRAEVISYDDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFRFNV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_006368_1	1.15\|191068\|34\|NC_006368\|CRISPRCasFinder,CRT	191068-191101	34	NZ_CP021285	Legionella pneumophila subsp. pneumophila strain Allentown 1 (D-7475) plasmid unnamed2, complete sequence	33767-33800	3	0.912
NC_006368_1	1.15\|191068\|34\|NC_006368\|CRISPRCasFinder,CRT	191068-191101	34	NC_006366	Legionella pneumophila str. Lens plasmid pLPL, complete sequence	43841-43874	3	0.912
NC_006368_3	3.8\|3078290\|27\|NC_006368\|CRT	3078290-3078316	27	NZ_CP053936	Bacillus thuringiensis strain FDAARGOS_794 plasmid unnamed4, complete sequence	11652-11678	4	0.852
NC_006368_3	3.8\|3078290\|27\|NC_006368\|CRT	3078290-3078316	27	NZ_CP053933	Bacillus thuringiensis strain FDAARGOS_794 plasmid unnamed2, complete sequence	41502-41528	4	0.852
NC_006368_3	3.8\|3078290\|27\|NC_006368\|CRT	3078290-3078316	27	NZ_CP009718	Bacillus thuringiensis strain HD682 plasmid pBGN_2, complete sequence	15494-15520	4	0.852
NC_006368_3	3.10\|3078389\|27\|NC_006368\|CRT	3078389-3078415	27	NZ_CP053936	Bacillus thuringiensis strain FDAARGOS_794 plasmid unnamed4, complete sequence	11652-11678	4	0.852
NC_006368_3	3.10\|3078389\|27\|NC_006368\|CRT	3078389-3078415	27	NZ_CP053933	Bacillus thuringiensis strain FDAARGOS_794 plasmid unnamed2, complete sequence	41502-41528	4	0.852
NC_006368_3	3.10\|3078389\|27\|NC_006368\|CRT	3078389-3078415	27	NZ_CP009718	Bacillus thuringiensis strain HD682 plasmid pBGN_2, complete sequence	15494-15520	4	0.852
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	MN693625	Marine virus AFVG_250M334, complete genome	30638-30671	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	NZ_CP020506	Serratia marcescens strain 95 plasmid unnamed1, complete sequence	6512-6545	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	NZ_CP022274	Citrobacter freundii strain 18-1 plasmid pA18-1, complete sequence	85367-85400	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	NZ_CP026551	Citrobacter sp. SL156 plasmid unnamed2	80071-80104	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	NZ_CP022697	Citrobacter farmeri strain AUSMDU00008141 plasmid pAUSMDU8141-2, complete sequence	56497-56530	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	NC_019013	Escherichia coli strain G3/10 plasmid pSYM1, complete sequence	9531-9564	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	CP052139	Klebsiella pneumoniae strain F17KP0040 plasmid pF17KP0040-1, complete sequence	96043-96076	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	MN699848	Citrobacter pasteurii strain 175G8 plasmid pCfr-OXA-198, complete sequence	136300-136333	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	NZ_KY416992	Escherichia coli strain FAM21805 plasmid unnamed, complete sequence	46142-46175	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	NZ_CP020508	Serratia marcescens strain BWH-35 plasmid unnamed, complete sequence	187130-187163	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	NZ_CP017222	Escherichia coli strain FAM21845 plasmid pFAM21845_2, complete sequence	38341-38374	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	NC_019254	Shigella sp. MO17 plasmid pMO17_54, complete sequence	16864-16897	7	0.794
NC_006368_1	1.2\|190142\|34\|NC_006368\|CRISPRCasFinder,CRT	190142-190175	34	NZ_CP049048	Enterobacter hormaechei strain Y233 plasmid p233-142, complete sequence	109547-109580	7	0.794
NC_006368_1	1.13\|190927\|31\|NC_006368\|CRISPRCasFinder,CRT	190927-190957	31	NZ_AP014824	Geminocystis sp. NIES-3709 plasmid pGM3709_03, complete sequence	8512-8542	9	0.71
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	NZ_CP040051	Acinetobacter baumannii strain VB16141 plasmid unnamed1, complete sequence	65151-65184	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	NZ_CP012007	Acinetobacter baumannii strain Ab04-mff plasmid pAB04-1, complete sequence	55277-55310	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	CP040054	Acinetobacter baumannii strain VB35179 plasmid unnamed1, complete sequence	51450-51483	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	NZ_CP012005	Acinetobacter baumannii strain ATCC 17978-mff plasmid pAB3, complete sequence	53921-53954	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	MF399199	Acinetobacter baumannii strain D46 plasmid pD46-4, complete sequence	177496-177529	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	NZ_AP014650	Acinetobacter baumannii strain IOMTU433 plasmid pIOMTU433, complete sequence	93937-93970	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	NZ_CP050433	Acinetobacter baumannii strain PM194229 plasmid pPM194229_1, complete sequence	119339-119372	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	LT605060	Acinetobacter calcoaceticus strain NCTC7364 genome assembly, plasmid: 2	43536-43569	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	NZ_KU744946	Acinetobacter baumannii strain A297 (RUH875) plasmid pA297-3 clone Global clone 1 (GC1), complete sequence	171009-171042	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	NZ_KT779035	Acinetobacter baumannii strain D4 plasmid pD4, complete sequence	103008-103041	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	NZ_MK323043	Acinetobacter baumannii strain Acb-45063 plasmid pAb45063_b, complete sequence	4445-4478	10	0.706
NC_006368_1	1.23\|191645\|34\|NC_006368\|CRISPRCasFinder,CRT	191645-191678	34	CP033562	Acinetobacter nosocomialis strain 2010S01-197 plasmid p2010S01-197-1, complete sequence	61395-61428	10	0.706
NC_006368_1	1.10\|190714\|34\|NC_006368\|CRISPRCasFinder,CRT	190714-190747	34	NC_019509	Cronobacter phage ESP2949-1, complete genome	8672-8705	12	0.647
NC_006368_1	1.10\|190714\|34\|NC_006368\|CRISPRCasFinder,CRT	190714-190747	34	MH845412	Cronobacter phage CS01, complete genome	13237-13270	12	0.647

1. spacer 1.15|191068|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP021285 (Legionella pneumophila subsp. pneumophila strain Allentown 1 (D-7475) plasmid unnamed2, complete sequence) position: , mismatch: 3, identity: 0.912

gaatttgtcggccgcatagaccgcttttatcaaa	CRISPR spacer
gaatttgtcggccgcatagaccgcttttatcgtt	Protospacer
*******************************.

2. spacer 1.15|191068|34|NC_006368|CRISPRCasFinder,CRT matches to NC_006366 (Legionella pneumophila str. Lens plasmid pLPL, complete sequence) position: , mismatch: 3, identity: 0.912

gaatttgtcggccgcatagaccgcttttatcaaa	CRISPR spacer
gaatttgtcggccgcatagaccgcttttatcgtt	Protospacer
*******************************.

3. spacer 3.8|3078290|27|NC_006368|CRT matches to NZ_CP053936 (Bacillus thuringiensis strain FDAARGOS_794 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.852

aaaggagaaacgggagcagtaggtcca	CRISPR spacer
acgggagaaacgggagcaacaggtcca	Protospacer
* .***************..*******

4. spacer 3.8|3078290|27|NC_006368|CRT matches to NZ_CP053933 (Bacillus thuringiensis strain FDAARGOS_794 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.852

aaaggagaaacgggagcagtaggtcca	CRISPR spacer
acgggagaaacgggagcaacaggtcca	Protospacer
* .***************..*******

5. spacer 3.8|3078290|27|NC_006368|CRT matches to NZ_CP009718 (Bacillus thuringiensis strain HD682 plasmid pBGN_2, complete sequence) position: , mismatch: 4, identity: 0.852

aaaggagaaacgggagcagtaggtcca	CRISPR spacer
acgggagaaacgggagcaacaggtcca	Protospacer
* .***************..*******

6. spacer 3.10|3078389|27|NC_006368|CRT matches to NZ_CP053936 (Bacillus thuringiensis strain FDAARGOS_794 plasmid unnamed4, complete sequence) position: , mismatch: 4, identity: 0.852

aaaggagaaacgggagcagtaggtcca	CRISPR spacer
acgggagaaacgggagcaacaggtcca	Protospacer
* .***************..*******

7. spacer 3.10|3078389|27|NC_006368|CRT matches to NZ_CP053933 (Bacillus thuringiensis strain FDAARGOS_794 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.852

aaaggagaaacgggagcagtaggtcca	CRISPR spacer
acgggagaaacgggagcaacaggtcca	Protospacer
* .***************..*******

8. spacer 3.10|3078389|27|NC_006368|CRT matches to NZ_CP009718 (Bacillus thuringiensis strain HD682 plasmid pBGN_2, complete sequence) position: , mismatch: 4, identity: 0.852

aaaggagaaacgggagcagtaggtcca	CRISPR spacer
acgggagaaacgggagcaacaggtcca	Protospacer
* .***************..*******

9. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to MN693625 (Marine virus AFVG_250M334, complete genome) position: , mismatch: 7, identity: 0.794

tcactactcctgaaggttataatttttgctataa	CRISPR spacer
tcactactcctgaaggttttaattggatatatga	Protospacer
****************** *****     ***.*

10. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP020506 (Serratia marcescens strain 95 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

11. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP022274 (Citrobacter freundii strain 18-1 plasmid pA18-1, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

12. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP026551 (Citrobacter sp. SL156 plasmid unnamed2) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

13. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP022697 (Citrobacter farmeri strain AUSMDU00008141 plasmid pAUSMDU8141-2, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

14. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to NC_019013 (Escherichia coli strain G3/10 plasmid pSYM1, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

15. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to CP052139 (Klebsiella pneumoniae strain F17KP0040 plasmid pF17KP0040-1, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

16. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to MN699848 (Citrobacter pasteurii strain 175G8 plasmid pCfr-OXA-198, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

17. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_KY416992 (Escherichia coli strain FAM21805 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

18. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP020508 (Serratia marcescens strain BWH-35 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

19. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP017222 (Escherichia coli strain FAM21845 plasmid pFAM21845_2, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

20. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to NC_019254 (Shigella sp. MO17 plasmid pMO17_54, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

21. spacer 1.2|190142|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP049048 (Enterobacter hormaechei strain Y233 plasmid p233-142, complete sequence) position: , mismatch: 7, identity: 0.794

tcactactcc-tgaaggttataatttttgctataa	CRISPR spacer
-catcactttatgaaggttattatttttgctaaaa	Protospacer
 **..***.. ********** ********** **

22. spacer 1.13|190927|31|NC_006368|CRISPRCasFinder,CRT matches to NZ_AP014824 (Geminocystis sp. NIES-3709 plasmid pGM3709_03, complete sequence) position: , mismatch: 9, identity: 0.71

attttaccttttaacacatattgataggcgt	CRISPR spacer
attttaccctttaacacatcttggaaacgag	Protospacer
********.********** ***. *.  .

23. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP040051 (Acinetobacter baumannii strain VB16141 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

24. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP012007 (Acinetobacter baumannii strain Ab04-mff plasmid pAB04-1, complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

25. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to CP040054 (Acinetobacter baumannii strain VB35179 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

26. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP012005 (Acinetobacter baumannii strain ATCC 17978-mff plasmid pAB3, complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

27. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to MF399199 (Acinetobacter baumannii strain D46 plasmid pD46-4, complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

28. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_AP014650 (Acinetobacter baumannii strain IOMTU433 plasmid pIOMTU433, complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

29. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_CP050433 (Acinetobacter baumannii strain PM194229 plasmid pPM194229_1, complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

30. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to LT605060 (Acinetobacter calcoaceticus strain NCTC7364 genome assembly, plasmid: 2) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

31. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_KU744946 (Acinetobacter baumannii strain A297 (RUH875) plasmid pA297-3 clone Global clone 1 (GC1), complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

32. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_KT779035 (Acinetobacter baumannii strain D4 plasmid pD4, complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

33. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to NZ_MK323043 (Acinetobacter baumannii strain Acb-45063 plasmid pAb45063_b, complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

34. spacer 1.23|191645|34|NC_006368|CRISPRCasFinder,CRT matches to CP033562 (Acinetobacter nosocomialis strain 2010S01-197 plasmid p2010S01-197-1, complete sequence) position: , mismatch: 10, identity: 0.706

ttcttttttcagatttcatttccttttccttgtg	CRISPR spacer
cctgatcttcagattcgatttccttttccttttc	Protospacer
...  *.********. ************** *

35. spacer 1.10|190714|34|NC_006368|CRISPRCasFinder,CRT matches to NC_019509 (Cronobacter phage ESP2949-1, complete genome) position: , mismatch: 12, identity: 0.647

ctaacctgattgctcaacaaataatgctattggc	CRISPR spacer
tacggttgattgcttaacaaaaaatgctatgatg	Protospacer
.  . .********.****** ******** .

36. spacer 1.10|190714|34|NC_006368|CRISPRCasFinder,CRT matches to MH845412 (Cronobacter phage CS01, complete genome) position: , mismatch: 12, identity: 0.647

ctaacctgattgctcaacaaataatgctattggc	CRISPR spacer
tacggttgattgcttaacaaaaaatgctatgatg	Protospacer
.  . .********.****** ******** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

216713 : 269636

Pseudomonas_phage(66.67%)

integrase,protease,transposase

attL 226438:226454|attR 234123:234139

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011212825.1\|216713_217922_+\|integrase	site-specific integrase	A0A1W6JTA0	Pseudomonas_phage	7.5e-93	47.8
WP_011212826.1\|218148_218973_+	hypothetical protein	NA	NA	NA	NA
WP_011212827.1\|218959_219922_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_011212828.1\|220252_222193_+	site-specific DNA-methyltransferase	A0A2L1IZ21	Streptomyces_phage	1.8e-56	34.9
WP_011212829.1\|222189_224688_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_011212831.1\|225538_226405_+\|transposase	transposase	NA	NA	NA	NA
226438:226454	attL	NA	NA	NA	NA
WP_011212832.1\|226595_229781_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_011212833.1\|230008_230875_+\|transposase	transposase	NA	NA	NA	NA
WP_025519216.1\|230879_231443_-	hypothetical protein	NA	NA	NA	NA
WP_011212835.1\|231769_232150_-	hypothetical protein	NA	NA	NA	NA
WP_080019877.1\|232228_232759_-\|integrase	tyrosine-type recombinase/integrase	A0A1W6JTA0	Pseudomonas_phage	2.9e-33	47.3
WP_011212836.1\|233167_234034_+\|transposase	transposase	NA	NA	NA	NA
WP_011212837.1\|234325_235429_+	nucleoside hydrolase	NA	NA	NA	NA
234123:234139	attR	NA	NA	NA	NA
WP_011212842.1\|240268_240784_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_162470335.1\|241108_241279_-	hypothetical protein	NA	NA	NA	NA
WP_011212844.1\|241673_241988_-	hypothetical protein	NA	NA	NA	NA
WP_011212845.1\|242282_243719_+	hypothetical protein	NA	NA	NA	NA
WP_011212846.1\|243979_244726_+	hypothetical protein	NA	NA	NA	NA
WP_011212847.1\|245073_245952_-	diguanylate cyclase	NA	NA	NA	NA
WP_011212848.1\|245981_247064_-	EAL domain-containing protein	NA	NA	NA	NA
WP_011212849.1\|247178_247940_-	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_010945919.1\|247920_248133_-	ParD-like family protein	NA	NA	NA	NA
WP_011212850.1\|248309_248789_-	hypothetical protein	NA	NA	NA	NA
WP_011212851.1\|249024_250002_+	hypothetical protein	NA	NA	NA	NA
WP_011212852.1\|250130_250550_-	YjbQ family protein	NA	NA	NA	NA
WP_011212853.1\|250974_251748_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_011212854.1\|251829_252285_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_011212855.1\|252452_253337_-	DUF808 domain-containing protein	NA	NA	NA	NA
WP_011212856.1\|253603_254014_-	peptide chain release factor-like protein	NA	NA	NA	NA
WP_011212857.1\|254114_254840_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_011212858.1\|254836_255523_-	MCE family protein	NA	NA	NA	NA
WP_011212859.1\|255590_256346_-	ABC transporter permease	NA	NA	NA	NA
WP_011212860.1\|256611_257178_-	F-box protein	NA	NA	NA	NA
WP_080019879.1\|257367_258093_+	hypothetical protein	NA	NA	NA	NA
WP_011212862.1\|258222_259083_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011212863.1\|259193_260243_+	L-tyrosine/L-tryptophan isonitrile synthase family protein	NA	NA	NA	NA
WP_011212864.1\|260232_261069_+	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_011212865.1\|261065_262508_+	FAD-binding protein	NA	NA	NA	NA
WP_011212866.1\|262504_263653_+	MFS transporter	NA	NA	NA	NA
WP_011212867.1\|263649_264882_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_011212868.1\|265039_266182_-	hypothetical protein	NA	NA	NA	NA
WP_025519229.1\|266721_267696_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_011212870.1\|267800_268619_+	hypothetical protein	NA	NA	NA	NA
WP_011212871.1\|268793_269636_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA

DBSCAN-SWA_2

793631 : 864669

uncultured_virus(14.29%)

tRNA,transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010946555.1\|793631_794717_+\|transposase	IS4-like element ISLpn9 family transposase	NA	NA	NA	NA
WP_010946556.1\|794742_795036_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_042233480.1\|795061_796207_+	ABC transporter permease	NA	NA	NA	NA
WP_011213249.1\|796215_797655_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_011213250.1\|797979_799761_-	lytic transglycosylase domain-containing protein	K4NWI2	Pseudomonas_phage	3.0e-13	35.8
WP_011213251.1\|799802_800456_-	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_011213252.1\|800669_801134_-	DoxX family protein	NA	NA	NA	NA
WP_011213253.1\|801130_801910_-	putative DNA-binding domain-containing protein	NA	NA	NA	NA
WP_011213254.1\|801902_802772_-	DUF692 domain-containing protein	NA	NA	NA	NA
WP_011213255.1\|802777_803032_-	DUF2282 domain-containing protein	NA	NA	NA	NA
WP_011213256.1\|803368_804394_+	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_011213257.1\|804509_806726_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011213258.1\|806767_807532_+	acetoacetate decarboxylase	NA	NA	NA	NA
WP_011213259.1\|807568_807841_+	DUF2282 domain-containing protein	NA	NA	NA	NA
WP_011213260.1\|807833_809147_+	adenylate/guanylate cyclase domain-containing protein	M1HLN3	Pelagibacter_phage	5.6e-17	27.7
WP_011213261.1\|809166_809982_-	putative DNA-binding domain-containing protein	NA	NA	NA	NA
WP_011213262.1\|809974_810802_-	DUF692 domain-containing protein	NA	NA	NA	NA
WP_010946414.1\|811099_811366_+	hypothetical protein	NA	NA	NA	NA
WP_011213263.1\|811620_812373_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_011213264.1\|812510_815252_+	bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase	NA	NA	NA	NA
WP_025519356.1\|815516_816728_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_011213266.1\|816795_817368_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_011213267.1\|817360_818287_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.6e-18	26.6
WP_025519358.1\|818301_819420_+	ABC transporter permease	NA	NA	NA	NA
WP_011213269.1\|819489_820809_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_011213270.1\|820898_822659_-	protein-disulfide reductase DsbD	NA	NA	NA	NA
WP_010946424.1\|822844_823135_+	co-chaperone GroES	A0A221S322	uncultured_virus	1.5e-18	48.9
WP_011213271.1\|823162_824809_+	chaperonin GroEL	A0A240F779	uncultured_virus	4.1e-174	60.1
WP_011213272.1\|824931_825372_+	DNA starvation/stationary phase protection protein	NA	NA	NA	NA
WP_011213273.1\|825628_827746_+	fused MFS/spermidine synthase	NA	NA	NA	NA
WP_011213274.1\|828079_829960_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	6.0e-97	36.2
WP_011213275.1\|830093_831902_+	dipeptide ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.8e-19	29.9
WP_011213276.1\|831990_836274_+	hypothetical protein	NA	NA	NA	NA
WP_011213277.1\|836631_838341_-\|tRNA	proline--tRNA ligase	A0A2K9L3R9	Tupanvirus	6.6e-10	30.1
WP_080019926.1\|838502_841352_+	Dot/Icm T4SS effector AnkX	A0A2L2DMI5	Acanthamoeba_polyphaga_mimivirus	1.6e-08	22.7
WP_080019927.1\|841358_843071_-\|holin	T4SS effector phosphocholine hydrolase Lem3	NA	NA	NA	NA
WP_010946434.1\|843157_845464_-	bifunctional SulP family inorganic anion transporter/carbonic anhydrase	NA	NA	NA	NA
WP_011213280.1\|845653_846505_-\|tRNA	tRNA 2-thiocytidine(32) synthetase TtcA	A0A0U2S5Z2	Escherichia_phage	8.8e-72	53.9
WP_010946436.1\|846522_847890_-	TolC family outer membrane protein	NA	NA	NA	NA
WP_011213281.1\|847901_848552_-	protein-L-isoaspartate O-methyltransferase	NA	NA	NA	NA
WP_011213282.1\|848732_849917_+	glycine C-acetyltransferase	V5LQ39	Emiliania_huxleyi_virus	1.0e-41	29.4
WP_011213283.1\|850003_851026_+	L-threonine 3-dehydrogenase	R9TPW0	Vibrio_phage	3.8e-13	62.7
WP_011213284.1\|851068_852742_+	energy-dependent translational throttle protein EttA	A0A2K9L0W2	Tupanvirus	1.1e-44	28.9
WP_010946441.1\|852783_853395_+	L,D-transpeptidase	NA	NA	NA	NA
WP_011213285.1\|853504_853942_+	YeeE/YedE family protein	NA	NA	NA	NA
WP_011213286.1\|853941_854367_+	transporter	NA	NA	NA	NA
WP_011213287.1\|854406_855579_-	outer membrane protein transport protein	NA	NA	NA	NA
WP_011213288.1\|855635_856610_-	DotI/IcmL/TraM family protein	NA	NA	NA	NA
WP_011213289.1\|856622_857582_-	formimidoylglutamase	NA	NA	NA	NA
WP_014841157.1\|857871_858681_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_011213291.1\|858680_859892_+	imidazolonepropionase	NA	NA	NA	NA
WP_011213292.1\|859918_860614_+	DUF3298 and DUF4163 domain-containing protein	NA	NA	NA	NA
WP_011213293.1\|860613_862614_+	oligopeptide transporter, OPT family	NA	NA	NA	NA
WP_021437009.1\|862998_863307_-\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_104411335.1\|863396_864126_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.5e-24	46.8
WP_021437011.1\|864102_864345_-\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_021437012.1\|864360_864669_-\|transposase	Tn3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1006172 : 1013012

Acinetobacter_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010946569.1\|1006172_1006949_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	3.3e-57	48.2
WP_010946570.1\|1006941_1007976_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	3.5e-75	47.6
WP_010946571.1\|1007953_1008532_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.0e-55	53.2
WP_010946572.1\|1008565_1009291_-	LPS export ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.1e-17	28.3
WP_010946573.1\|1009287_1009797_-	lipopolysaccharide transport periplasmic protein LptA	NA	NA	NA	NA
WP_010946574.1\|1009777_1010347_-	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_011213328.1\|1010343_1010871_-	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	1.4e-27	47.7
WP_010946576.1\|1010884_1011847_-	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	4.2e-38	34.1
WP_010946577.1\|1012214_1013012_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	1.3e-21	33.8

DBSCAN-SWA_4

1315908 : 1321845

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011213534.1\|1315908_1316982_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	9.5e-31	27.8
WP_011213535.1\|1316966_1317581_+	riboflavin synthase	A0A2I2L4R9	Orpheovirus	4.6e-22	38.4
WP_011213536.1\|1317577_1318786_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.0e-97	48.0
WP_010946914.1\|1318793_1319261_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	9.2e-23	49.1
WP_010946915.1\|1319386_1321024_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	3.6e-154	52.3
WP_010946916.1\|1321020_1321845_+	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	1.8e-53	43.9

DBSCAN-SWA_5

2042731 : 2114437

Tupanvirus(18.18%)

integrase,tRNA,transposase,protease

attL 2048174:2048233|attR 2097886:2097948

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010947570.1\|2042731_2043169_+\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_010947571.1\|2043386_2044169_+	VacJ family lipoprotein	NA	NA	NA	NA
WP_011214098.1\|2044277_2045237_-	glutathione synthase	NA	NA	NA	NA
WP_011214099.1\|2045236_2046532_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_010946556.1\|2046690_2046984_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_010946555.1\|2047009_2048095_-\|transposase	IS4-like element ISLpn9 family transposase	NA	NA	NA	NA
2048174:2048233	attL	NA	NA	NA	NA
WP_011214101.1\|2048547_2049444_+	DMT family transporter	NA	NA	NA	NA
WP_011214102.1\|2049447_2049729_+	hypothetical protein	NA	NA	NA	NA
WP_021437159.1\|2049715_2050066_+	sulfurtransferase	NA	NA	NA	NA
WP_011214104.1\|2050099_2050762_-	Dot/Icm T4SS effector Lem14	NA	NA	NA	NA
WP_011214105.1\|2051131_2052769_+	alkaline phosphatase family protein	NA	NA	NA	NA
WP_014841922.1\|2052821_2053460_+	uridine kinase	A0A2K9L178	Tupanvirus	1.7e-27	36.7
WP_027229338.1\|2053573_2054362_+	enoyl-ACP reductase	NA	NA	NA	NA
WP_080454273.1\|2054813_2057654_-	hypothetical protein	NA	NA	NA	NA
WP_011214109.1\|2058160_2058787_+	hypothetical protein	NA	NA	NA	NA
WP_011214110.1\|2059069_2062204_-	hypothetical protein	NA	NA	NA	NA
WP_011214111.1\|2062776_2064651_-	SurA N-terminal domain-containing protein	NA	NA	NA	NA
WP_011214112.1\|2064908_2065187_-	HU family DNA-binding protein	B5TA87	Burkholderia_phage	2.5e-15	49.4
WP_010947583.1\|2065315_2067766_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	5.1e-213	50.2
WP_172407122.1\|2067999_2069280_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.9e-134	57.2
WP_010947585.1\|2069414_2070059_-	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.2e-57	59.5
WP_010947586.1\|2070061_2071393_-	trigger factor	NA	NA	NA	NA
WP_011214115.1\|2072263_2073490_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_011214116.1\|2073612_2075463_+	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	5.6e-71	32.8
WP_011214117.1\|2075490_2076165_-	ribonuclease III	A0A0P0BX11	Ostreococcus_lucimarinus_virus	7.5e-26	33.8
WP_011214118.1\|2076154_2076547_-	DUF4845 domain-containing protein	NA	NA	NA	NA
WP_011214119.1\|2076558_2077314_-	signal peptidase I	NA	NA	NA	NA
WP_010947592.1\|2077421_2079254_-	elongation factor 4	E4ZFJ7	Streptococcus_phage	2.8e-22	25.2
WP_011214120.1\|2079448_2080465_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_011214121.1\|2080539_2081679_+	GspL family type II secretion system protein LspL	NA	NA	NA	NA
WP_011214122.1\|2081675_2082146_+	GspM family type II secretion system protein LspM	NA	NA	NA	NA
WP_011214123.1\|2082249_2082783_-	SPOR domain-containing protein	NA	NA	NA	NA
WP_011214124.1\|2083057_2084383_+	deoxyguanosinetriphosphate triphosphohydrolase family protein	NA	NA	NA	NA
WP_014844191.1\|2084646_2087877_+	hypothetical protein	NA	NA	NA	NA
WP_011214126.1\|2088755_2090288_+	alpha,alpha-trehalase	NA	NA	NA	NA
WP_014844192.1\|2090308_2091373_-	hypothetical protein	NA	NA	NA	NA
WP_011214128.1\|2091464_2091905_-	VOC family protein	NA	NA	NA	NA
WP_010947600.1\|2092139_2092667_+	TIGR00645 family protein	K4K6D8	Caulobacter_phage	1.7e-20	33.8
WP_011214129.1\|2092903_2094121_+	Dot/Icm T4SS effector LegC2/YlfB	NA	NA	NA	NA
WP_011214130.1\|2094442_2094757_+	hypothetical protein	NA	NA	NA	NA
WP_011214131.1\|2094921_2096031_-	hypothetical protein	NA	NA	NA	NA
WP_011214132.1\|2096461_2097547_+\|transposase	IS4-like element ISLpn9 family transposase	NA	NA	NA	NA
WP_010946556.1\|2097572_2097866_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_011214133.1\|2098043_2098319_-	acylphosphatase	NA	NA	NA	NA
2097886:2097948	attR	NA	NA	NA	NA
WP_011214134.1\|2098475_2098829_+	hypothetical protein	NA	NA	NA	NA
WP_011214135.1\|2099010_2100342_-	Lpg1888 family Dot/Icm type IV secretion system effector	NA	NA	NA	NA
WP_011214136.1\|2100570_2101536_+	alpha/beta hydrolase	M1PGN2	Moumouvirus	1.9e-78	46.6
WP_080020008.1\|2101599_2103321_-	Dot/Icm T4SS effector LegLC8	NA	NA	NA	NA
WP_013101554.1\|2103432_2103699_+	hypothetical protein	NA	NA	NA	NA
WP_011214139.1\|2103752_2104172_+	hypothetical protein	NA	NA	NA	NA
WP_011214140.1\|2104181_2105462_-	MFS transporter	NA	NA	NA	NA
WP_011214141.1\|2105938_2107219_+	chloride channel protein	NA	NA	NA	NA
WP_021437098.1\|2107417_2107633_-\|transposase	transposase	NA	NA	NA	NA
WP_011214143.1\|2107801_2108908_-	hypothetical protein	NA	NA	NA	NA
WP_011214144.1\|2109109_2109613_+	hypothetical protein	NA	NA	NA	NA
WP_011214145.1\|2109876_2110356_+	YchJ family protein	NA	NA	NA	NA
WP_011214146.1\|2110375_2112181_+	cation:proton antiporter	NA	NA	NA	NA
WP_011214148.1\|2113757_2114093_+	endonuclease domain-containing protein	NA	NA	NA	NA
WP_021437102.1\|2114116_2114437_-\|transposase	transposase	A0A0N9SHJ4	Paenibacillus_phage	3.0e-09	39.1

DBSCAN-SWA_6

2261893 : 2272016

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011214266.1\|2261893_2263582_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	8.0e-16	30.4
WP_011214267.1\|2263713_2264721_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_011214268.1\|2264844_2266170_-	adenosylhomocysteinase	S4VPF6	Pandoravirus	1.8e-47	31.2
WP_011214269.1\|2266188_2267337_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	7.6e-127	58.5
WP_011214270.1\|2267545_2268658_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	1.7e-51	35.4
WP_010947740.1\|2268753_2269893_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.6e-23	26.9
WP_011214271.1\|2270081_2272016_-	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	3.8e-147	49.4

DBSCAN-SWA_7

2648137 : 2656383

Moraxella_phage(16.67%)

integrase,tRNA,transposase

attL 2652294:2652306|attR 2657239:2657251

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015961445.1\|2648137_2649139_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	3.4e-91	50.7
WP_010948064.1\|2649343_2649583_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_014842313.1\|2649785_2650229_+	lpg2359 family Dot/Icm T4SS effector	A0A292GL36	Xanthomonas_phage	1.1e-20	43.2
WP_015961446.1\|2650237_2651971_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	4.6e-59	35.5
WP_014844507.1\|2652057_2653923_+	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.3e-35	32.8
2652294:2652306	attL	NA	NA	NA	NA
WP_011213396.1\|2654263_2655439_-\|transposase	ISL3-like element ISLpn11 family transposase	A9YX10	Burkholderia_phage	3.2e-16	22.9
WP_032831057.1\|2655504_2656383_-\|integrase	tyrosine-type recombinase/integrase	A0A059VF45	Pseudomonas_phage	5.9e-71	46.7
2657239:2657251	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_006368

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection