CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_013853	Streptococcus mitis B6, complete genome	4 crisprs	csa3,DEDDh,PrimPol,cas3,DinG,WYL,RT	1	1	15	2

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_013853_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013853_1

879374-879547

Orphan

Consensus_repeat	Method
AACTTCTAAAACTAACTTCCAGTTT	CRISPRCasFinder

2 spacers

DinG

The CRISPR arrays of NC_013853_1

>merge|NC_013853|1|879374-879547|CRISPRCasFinder
AACTTCTAAAACTAACTTCCAGTTTTGGGAGAGAGATGGAAGTTACTTTGAGAAGTTACGAGTAAAAGAAAAGGTAACTTCTAAAACTAACTTCCAGTTTCCCACAACCTAGCTTTTAGTATGAGAAAAATGCGTGAAATCAGTGGAAATCCGTCTTAGACTAACTTCCACTGG

>NC_013853|1|1|879374-879547|CRISPRCasFinder
AACTTCTAAAACTAACTTCCAGTTT	TGGGAGAGAGATGGAAGTTACTTTGAGAAGTTACGAGTAAAAGAAAAGGT
AACTTCTAAAACTAACTTCCAGTTT	CCCACAACCTAGCTTTTAGTATGAGAAAAATGCGTGAAATCAGTGGAAA
TCCGTCTTAGACTAACTTCCACTGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_013853.1\|WP_000745687.1\|884872_885334_+\|signal-peptidase-II	unknown	unknown	gnl\|CDD\|184825
NC_013853.1\|WP_000159648.1\|868653_869916_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NC_013853.1\|WP_000109141.1\|881196_881511_+\|50S-ribosomal-protein-L21	unknown	unknown	gnl\|CDD\|235510
NC_013853.1\|WP_000727870.1\|887395_889279_+\|phosphorylcholine-esterase-CbpE	unknown	unknown	gnl\|CDD\|227588
NC_013853.1\|WP_012972504.1\|889358_890489_+\|glutamate-5-kinase	unknown	unknown	gnl\|CDD\|223341
NC_013853.1\|WP_000613699.1\|881526_881871_+\|ribosomal-processing-cysteine-protease-Prp	unknown	unknown	gnl\|CDD\|225423
NC_013853.1\|WP_000720654.1\|873134_874376_-\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600
NC_013853.1\|WP_000797050.1\|871637_873050_+\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NC_013853.1\|WP_000114494.1\|867855_868626_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NC_013853.1\|WP_000916509.1\|881887_882181_+\|50S-ribosomal-protein-L27	unknown	unknown	gnl\|CDD\|235464
NC_013853.1\|WP_000163002.1\|882601_883768_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NC_013853.1\|WP_000887749.1\|869926_871153_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NC_013853.1\|WP_000915878.1\|878323_879301_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_013853.1\|WP_000488875.1\|874478_875588_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|279875
NC_013853.1\|WP_001218461.1\|871139_871568_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NC_013853.1\|WP_000850560.1\|877244_878327_-\|DEAD/DEAH-box-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|223587
NC_013853.1\|WP_001040725.1\|875793_876990_+\|elongation-factor-Tu	unknown	unknown	gnl\|CDD\|234596
NC_013853.1\|WP_000163006.1\|879714_880881_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NC_013853.1\|WP_000403233.1\|885323_886211_+\|RluA-family-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NC_013853.1\|WP_001025693.1\|883967_884876_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656

Protein	Function_ID	Function_description	E-value
NC_013853.1\|WP_000745687.1\|884872_885334_+\|signal-peptidase-II	gnl\|CDD\|184825	PRK14797, PRK14797, lipoprotein signal peptidase; Provisional.	3.73354e-71
NC_013853.1\|WP_000159648.1\|868653_869916_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	3.19306e-135
NC_013853.1\|WP_000109141.1\|881196_881511_+\|50S-ribosomal-protein-L21	gnl\|CDD\|235510	PRK05573, rplU, 50S ribosomal protein L21; Validated.	6.1021e-45
NC_013853.1\|WP_000727870.1\|887395_889279_+\|phosphorylcholine-esterase-CbpE	gnl\|CDD\|227588	COG5263, COG5263, FOG: Glucan-binding domain (YG repeat) [General function prediction only].	4.78206e-67
NC_013853.1\|WP_012972504.1\|889358_890489_+\|glutamate-5-kinase	gnl\|CDD\|223341	COG0263, ProB, Glutamate 5-kinase [Amino acid transport and metabolism].	3.53733e-176
NC_013853.1\|WP_000613699.1\|881526_881871_+\|ribosomal-processing-cysteine-protease-Prp	gnl\|CDD\|225423	COG2868, COG2868, Predicted ribosomal protein [Translation, ribosomal structure and biogenesis].	1.01101e-37
NC_013853.1\|WP_000720654.1\|873134_874376_-\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	9.21342e-112
NC_013853.1\|WP_000797050.1\|871637_873050_+\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_013853.1\|WP_000114494.1\|867855_868626_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.94329e-147
NC_013853.1\|WP_000916509.1\|881887_882181_+\|50S-ribosomal-protein-L27	gnl\|CDD\|235464	PRK05435, rpmA, 50S ribosomal protein L27; Validated.	6.08512e-51
NC_013853.1\|WP_000163002.1\|882601_883768_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.71285e-36
NC_013853.1\|WP_000887749.1\|869926_871153_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_013853.1\|WP_000915878.1\|878323_879301_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.99005e-46
NC_013853.1\|WP_000488875.1\|874478_875588_+\|AI-2E-family-transporter	gnl\|CDD\|279875	pfam01594, AI-2E_transport, AI-2E family transporter. This family includes four different proteins from E. coli alone. One of them, YdgG or TqsA, has been shown to mediate transport of the quorum-sensing signal autoinducer 2 (AI-2). It is not clear if TqsA enhances secretion of AI-2 or inhibits AI-2 uptake. By altering the intracellular concentration of AI-2, TqsA affects gene expression in biofilms and biofilm formation. TsqA belongs to the AI-2 exporter (AI-2E) superfamily.	2.75393e-65
NC_013853.1\|WP_001218461.1\|871139_871568_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	5.75042e-71
NC_013853.1\|WP_000850560.1\|877244_878327_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	6.78317e-105
NC_013853.1\|WP_001040725.1\|875793_876990_+\|elongation-factor-Tu	gnl\|CDD\|234596	PRK00049, PRK00049, elongation factor Tu; Reviewed.	0
NC_013853.1\|WP_000163006.1\|879714_880881_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	4.43709e-37
NC_013853.1\|WP_000403233.1\|885323_886211_+\|RluA-family-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	4.10115e-125
NC_013853.1\|WP_001025693.1\|883967_884876_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	8.52258e-35

>NC_013853.1|WP_000915878.1|878323_879301_-|Gfo/Idh/MocA-family-oxidoreductase
MLKLGVIGTGAISHHFIEAAHASGKYQLVAVYSRKLETAATFASRYQSIQLFDQVEDFFKNSFDVVYIASPNSLHFAQARAALSAGKHVILEKPAVTQPQEWVDLRHTAEKNHCFIFEAARNYHEKAFTIIKNFLADKQILGADFNYAKYSSKMPNLLTGETPNVFSDRFAGGALMDLGIYPLYATVRLFGKSQDATYQAQQLDNSIDLNGDGILFYPDFQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHVSSAIFTDHQGNQIQLPIQQAPHTMTEEVGAFAHMIQQPDLNLYQTWLEDASSVHELLYTMRQTAGIRFEAEK
>NC_013853.1|WP_000850560.1|877244_878327_-|DEAD/DEAH-box-helicase
MKTKLPTEWQELSDQLGFQEFTPIQTQLFDPLLAGENLLGVSPTGTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWSEAIGLTAQLFLSGSSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFVEKITHYAPRDHQLVYMSATTKFDQEKISPNTRTIDLSDQKLDNIQHFYMQVDQRHRIDLLRKLAHVEDFRGLVFFNSLSDLGSVEEKLQYRDILAVSLASDVNVKFRKVILEKFKDRQLTLLLATDLLARGIDIDSLECVVNFDVPRDIETYTHRAGRTGRMGKEGYVITLVTHPEELKKLKKFASVREIVLKNQELYIK
>NC_013853.1|WP_001040725.1|875793_876990_+|elongation-factor-Tu
MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDTKYEDIVMELMNTVDEYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAGDNVGVLLRGIQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGMVTEIEA
>NC_013853.1|WP_000488875.1|874478_875588_+|AI-2E-family-transporter
MFRKNKLFFWTSEILLLTIIFYLWREMGAIITPFVSVANTIMIPFLLGGFLYYLTNPIVNFLQKYFKINRIIGILLTLCALVWGLVIGVVYFLPILINQLTSLIATSQTIYSRLQDLIVDLSTYPAFQNLDIQATIQQLNLSYVDILQNILNSVTNSVGSVLSALFSTVLIIIMTPVFLVYFLLDGHKFLPMLERTVLKRDKLHIAGLLKNLNATIARYISGVAIDAIIIGCLAFIGYSVIGLKYALVFAIFSGLANLIPYVGPSIGLIPMIIANIFTDPHRMLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVIGMIVAVPTYSILKEISKFLSRLYENHKIMKERERQLAK
>NC_013853.1|WP_000720654.1|873134_874376_-|D-alanyl-D-alanine-carboxypeptidase
MKKIILTLLSLSLIGSASTVAAQDFNITAKHAIAVEANTGKILYEKEATQPVEIASITKLLTVYLVYEALENGSITLSTPVDISDYPYKLTTNSEASNVPMEARNYTVEQLLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTTGLNNETLGDNIYPGSKKDDENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTITSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPYARFTATSSLMDYISSTFTLRKIVQKGDAYQDSKAPVQDGKENMVTAVAKDDISLIERVGSQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDNDLIGQGYITTERPSFEMVAEKKVEKAFFLKVWWNQFIRFINEKL
>NC_013853.1|WP_000797050.1|871637_873050_+|Fe-S-cluster-assembly-protein-SufB
MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEDVIRELSAAKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPEKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPDLFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENTGQFERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNLVTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGAKMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELPMEYAVELNRLISYEMEGSVG
>NC_013853.1|WP_001218461.1|871139_871568_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MALSKLDSLYMAVVADHSKNPHHQGKLDDAEQISLNNPTCGDVINLSVKFDAENRLEDIAFLNSGCTISTASASMMTDAVFGKTKQEILELATIFSEMVQGQKDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIEN
>NC_013853.1|WP_000887749.1|869926_871153_+|cysteine-desulfurase
MLDVEVIRKDFPILDQIVNDEPLVYLDNAATTQKPLAVLETINRYYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVARYAEEVLTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMDDLRVKLTDRVKFVSLAHASNVLGVVNPIKEIAQMAHQVGAIMVVDGAQSTPHMKIDVQDLDVDFFAFSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQAASWKELPWKFEAGTPNMAGAIGLAAAVDYLEKIGMDAIEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVIAFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLDVPATARASFYIYNTKADCDKLVDALQKTKEFFNGTF
>NC_013853.1|WP_000159648.1|868653_869916_+|Fe-S-cluster-assembly-protein-SufD
MTKENIKLFSEMHAEPSWLADLRQKAFDKIDTLELPDIERVKFHRWNLGDGTITESEPSANVPDFTALDNHLKLVQVGTQTVFEQIPVELAEQGVVFTDFHSALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEIKEPIEGIFYQDSDSDVPFNKHIMIIAGKNSKISYLERLESRGEGSAKATANITVEVIARSGAQVKFAAIDRLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSSGRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVLMLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGFLGSVIVEIPVKEVRDEMIATIEEKLSKR
>NC_013853.1|WP_000114494.1|867855_868626_+|Fe-S-cluster-assembly-ATPase-SufC
MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKSTLSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLRAAMNAGKEDDEKTSVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLLMLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHVMMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL
>NC_013853.1|WP_000163006.1|879714_880881_-|IS30-family-transposase
MTKKQKHLTLEDRIDIQTGISQQETFRSIAEKMGKDPSTISKEIKRNRIMHPTSVKSDCTDCPLLKKAPYVCNNCPKKRTDCGFNRYLYYAKKAQEQYETMLRESRQGIPLNKESFYQMDKILTQGIQKKQSIYHIIQTHNLPVSKATVYRHAKLGYLTAKPIDFPRMVTFKERRKSRKVAIPKELKIGRTYQDFQELRETDDFFKWLEMDTVIGRPGGKLLLTFNVSFCNFLFALLLDNKTALEVATKFAALKERVMDGGYAFHQLFPVILTDNGSEFAYVEELERDIDGKSHLYFCDPSRPDQKGRIEKNHTVLRAILPKGTSFDQLTQKDVNLVISHVNSLKREEFQGKSAYDVFTFTFGEDIAALLGCQFVKPEDTHLSPDLLK
>NC_013853.1|WP_000109141.1|881196_881511_+|50S-ribosomal-protein-L21
MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVGGENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAINA
>NC_013853.1|WP_000613699.1|881526_881871_+|ribosomal-processing-cysteine-protease-Prp
MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINFINSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENSSEFVQTRVITEN
>NC_013853.1|WP_000916509.1|881887_882181_+|50S-ribosomal-protein-L27
MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTGGSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK
>NC_013853.1|WP_000163002.1|882601_883768_-|IS30-family-transposase
MTKKQKHLTLEDRIDIQTGISQQETFRSIAEKMGKDPSTISKEIKRNRIMHPTSVKSDCTDCPLLKKAPYVCNNCPKKRTDCGFNRYLYYAKKAQEHYETMLRESRQGIPLNKESFYQMDKILTLGIQKKQSIYHIIQTHNLPVSKATVYRHAKLGYLTAKPIDFPRMVTFKERRKSRKVAIPKELKIGRTYQDFQELRETDDFFKWLEMDTVIGRPGGKLLLTFNVSFCNFLFALLLDNKTALEVATKFAALKERVMDGGYAFHQLFPVILTDNGSEFAYVEELERDIDGKSHLYFCDPSRPDQKGRIEKNHTVLRAILPKGTSFDQLTQKDVNLVISHVNSLKREEFQGKSAYDVFTFTFGEDIAALLGCQFVKPEDTHLSPDLLK
>NC_013853.1|WP_001025693.1|883967_884876_+|LysR-family-transcriptional-regulator
MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELGFKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSIASQHYDFLPPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKLGLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDTSASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKREEVELSQAGTLFVEVMQEYFDQKRKS
>NC_013853.1|WP_000745687.1|884872_885334_+|signal-peptidase-II
MKKRGIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSLTYLQNRGAAFSILQNQQLLFAIITLLVVVGAIWYLHKHMEDSLWMVLGLTLIIAGGLGNFIDRISQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN
>NC_013853.1|WP_000403233.1|885323_886211_+|RluA-family-pseudouridine-synthase
MEIKIETGSLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKKAKYTVQEGDVVTYHVPEPEVLEYVAENIPLEIIYQDEDVAVVNKPQGMVVHPSAGHTSGTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDEAHLALAQDLKDKKSLRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLVELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGETLEFTADIPEIFKETLERLRK
>NC_013853.1|WP_000727870.1|887395_889279_+|phosphorylcholine-esterase-CbpE
MKKKLISLALAGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSDAIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRHLKELGVQKLDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQTAAEKGVSVIQNITQGEAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKVNGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHYDTNKSNTKDFIKNLSPSLIVQTSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGFVNISTSYKHIPNFQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFYLTDSGASAKNWKKINGSWYYFNKENQMETGWFNTGGQTYYLSNDGDMITGWRKIDGQWYYFAQSGEMKTGWVKDKETWYYMDSTGIMKTGEIEVAGQHYYLEDSGAMKQGWLKKANDWYFYKTDGSRAVGWIKDRDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPVEKSATIKTTSNSEIKESKEVVKKDLENKETSQHESITSSSTSQDLTSSTSQSSETTANKSESAQ
>NC_013853.1|WP_012972504.1|889358_890489_+|glutamate-5-kinase
MKNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKAITQQLAMLHEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQIVSAQILLTQDDFVDKRRYKNAHQALSVLLSRGAIPIINENDSVVIDELKVGDNDTLSAQVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTGGMLTKIKAATIATESGVPVYICSSLKSDAMIEAAEETKDGSYFVAQEKGLRTQKQWLAFYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVDAEGAFSYGDIVTVFDKESGKSLGKGRVQFGASALKDMLRSQKAKGVLIHRDDWISITPEIQLLFTEF

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Crispr_ID: NC_013853_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013853_2

1297103-1297205

Orphan

Consensus_repeat	Method
GGTAACTTCTAAAACTAACTTCCAGTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_013853_2

>merge|NC_013853|2|1297103-1297205|CRISPRCasFinder
GGTAACTTCTAAAACTAACTTCCAGTTTTGGGAGAGAGATGGAAGTTACTTTGAGAAGTTACGAGTAAAAGAAAAGGTAACTTCTAAAACTAACTTCCAGTTT

>NC_013853|2|2|1297103-1297205|CRISPRCasFinder
GGTAACTTCTAAAACTAACTTCCAGTTT	TGGGAGAGAGATGGAAGTTACTTTGAGAAGTTACGAGTAAAAGAAAA
GGTAACTTCTAAAACTAACTTCCAGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_013853.1\|WP_000359027.1\|1313483_1314020_-\|F0F1-ATP-synthase-subunit-delta	unknown	unknown	gnl\|CDD\|235593
NC_013853.1\|WP_000120838.1\|1291775_1292417_-\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NC_013853.1\|WP_000558549.1\|1314019_1314514_-\|F0F1-ATP-synthase-subunit-B	unknown	unknown	gnl\|CDD\|180240
NC_013853.1\|WP_000780836.1\|1287879_1288497_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
NC_013853.1\|WP_000954113.1\|1286555_1287398_+\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NC_013853.1\|WP_001065935.1\|1292556_1293786_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NC_013853.1\|WP_000182488.1\|1290287_1291127_-\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217
NC_013853.1\|WP_125393602.1\|1299932_1300532_+\|transposase	unknown	unknown	gnl\|CDD\|225995
NC_013853.1\|WP_000435446.1\|1293775_1294942_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NC_013853.1\|WP_000996630.1\|1311963_1313469_-\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|236448
NC_013853.1\|WP_000891752.1\|1291136_1291766_-\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NC_013853.1\|WP_000094352.1\|1309577_1310984_-\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|236447
NC_013853.1\|WP_000665633.1\|1298814_1299828_+\|lactonase-family-protein	unknown	unknown	gnl\|CDD\|225333
NC_013853.1\|WP_000527121.1\|1300610_1308035_-\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	unknown	unknown	gnl\|CDD\|173412
NC_013853.1\|WP_001085921.1\|1287397_1287883_+\|aminoacyl-tRNA-deacylase	unknown	unknown	gnl\|CDD\|237976
NC_013853.1\|WP_000102471.1\|1288735_1290226_+\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234778
NC_013853.1\|WP_000747539.1\|1295059_1297042_-\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869
NC_013853.1\|WP_000163007.1\|1297446_1298613_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NC_013853.1\|WP_000068046.1\|1309147_1309567_-\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|234796
NC_013853.1\|WP_000301214.1\|1311069_1311948_-\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|235535

Protein	Function_ID	Function_description	E-value
NC_013853.1\|WP_000359027.1\|1313483_1314020_-\|F0F1-ATP-synthase-subunit-delta	gnl\|CDD\|235593	PRK05758, PRK05758, F0F1 ATP synthase subunit delta; Validated.	6.34562e-46
NC_013853.1\|WP_000120838.1\|1291775_1292417_-\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	9.46083e-67
NC_013853.1\|WP_000558549.1\|1314019_1314514_-\|F0F1-ATP-synthase-subunit-B	gnl\|CDD\|180240	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated.	6.2461e-44
NC_013853.1\|WP_000780836.1\|1287879_1288497_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	6.05853e-55
NC_013853.1\|WP_000954113.1\|1286555_1287398_+\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	9.62449e-83
NC_013853.1\|WP_001065935.1\|1292556_1293786_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	8.23871e-11
NC_013853.1\|WP_000182488.1\|1290287_1291127_-\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.12683e-117
NC_013853.1\|WP_125393602.1\|1299932_1300532_+\|transposase	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.43002e-39
NC_013853.1\|WP_000435446.1\|1293775_1294942_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	2.78171e-63
NC_013853.1\|WP_000996630.1\|1311963_1313469_-\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|236448	PRK09281, PRK09281, F0F1 ATP synthase subunit alpha; Validated.	0
NC_013853.1\|WP_000891752.1\|1291136_1291766_-\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	5.22943e-110
NC_013853.1\|WP_000094352.1\|1309577_1310984_-\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0
NC_013853.1\|WP_000665633.1\|1298814_1299828_+\|lactonase-family-protein	gnl\|CDD\|225333	COG2706, COG2706, 3-carboxymuconate cyclase [Carbohydrate transport and metabolism].	2.25898e-160
NC_013853.1\|WP_000527121.1\|1300610_1308035_-\|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein	gnl\|CDD\|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	1.78538e-20
NC_013853.1\|WP_001085921.1\|1287397_1287883_+\|aminoacyl-tRNA-deacylase	gnl\|CDD\|237976	cd00002, YbaK_deacylase, This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS) inserted (INS) editing domain. The bacterial amino acid trans-editing enzyme YbaK is a deacylase that hydrolyzes cysteinyl-tRNA(Pro)'s mischarged by prolyl-tRNA synthetase. YbaK also hydrolyzes glycyl-tRNA's, alanyl-tRNA's, seryl-tRNA's, and prolyl-tRNA's. YbaK is homologous to the INS domain of prolyl-tRNA synthetase (ProRS) as well as the trans-editing enzyme ProX of Aeropyrum pernix which hydrolyzes alanyl-tRNA's and glycyl-tRNA's.	5.78779e-60
NC_013853.1\|WP_000102471.1\|1288735_1290226_+\|lysine--tRNA-ligase	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
NC_013853.1\|WP_000747539.1\|1295059_1297042_-\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.50192e-106
NC_013853.1\|WP_000163007.1\|1297446_1298613_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	6.76161e-37
NC_013853.1\|WP_000068046.1\|1309147_1309567_-\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|234796	PRK00571, atpC, F0F1 ATP synthase subunit epsilon; Validated.	8.94987e-48
NC_013853.1\|WP_000301214.1\|1311069_1311948_-\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|235535	PRK05621, PRK05621, F0F1 ATP synthase subunit gamma; Validated.	4.68103e-144

>NC_013853.1|WP_000747539.1|1295059_1297042_-|peptide-ABC-transporter-substrate-binding-protein
MKKRVFLAAGVAVLSVAVLAACSSGNGNKEATKPVTYTYVFSSDPATLDYTVSGQKSTKQITGNVIDGLLENDQYGNLVPSVAEDWTVSKDGLTYTYKIRKGIKWYTNEGEEYGEVKAQDFVTGLKHAADKKSEALYLVQDSIKGLDDYVNGKTTDFSTVGVKATDDYTVVYTLNHPESFWNSKTTMGILAPVSEDFLASKGDDFGKATDVTSILYNGAYLLKGLTSKSSIEMTKNQNYWDKQNVFIDDIKLSYFDGQDADSLGRGFDEGNYPAAPLFKNSANYERLKEKYKDNIIYSQQQGTTFYISTNIDRVAYNHTAKTSDVEKSSTKKALLNKDFRQSLAFATDRKAGISQVFGDEVAPRKLRTSLTPPTFVQVGEQSFGQVAKAELDKLDGVWKDVSLDDAQDSLHNVDKAKTKFEAAKKTLQADGVQFPIHLDIPVSSTRPEFVRQAQSYKQSVEEAIGADNVVVDIQQVSDDELASMTVLATSNTNTDWDINANSGWGPDYADPSTYLDIFDPTSGPNLLGSLGVVPGKDSSAIKAVGLDKFKELITDANSEKTNLEKRYAKYAKAQAWLTDSALVIPVHSDGAQMLVTKKVLGTGAGGWVGDKTSENSYKYLKIQDKIVTTKEMDEFRKKFADEKAKSNADYQKNLDRHIQD
>NC_013853.1|WP_000435446.1|1293775_1294942_-|AI-2E-family-transporter
MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISFLFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKINRVIAISIVFVIIALFIIWGLAVAIPNLQRQVLTFARNVPIYLEDADRVINDLVTKRLPDDFRPQLEQVLTNFSSQATVWASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRHYLTQFMPTKLKEPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFMIFFKIIGLRYAVTLGVTAGILNLVPYLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVLFVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ
>NC_013853.1|WP_001065935.1|1292556_1293786_-|tetratricopeptide-repeat-protein
MNNSQQMLQALEEQDLAKAEHCFVKALENDPSVLLYELATYLEGIGFYPQAKEIYLKIVEDFPEVNLNLAAIASEDGQIEEAFAYLEEIQADSDWYVSALALKADLYQLEGLTDVAREKLLEALTYSEDPLLILGLAELDSELENYQEAIQGYAQLDNRTIYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQKAVLYFKQIDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQFSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLTKWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGYFEEAKVNAQAYLKLVPDDVQMQELYERL
>NC_013853.1|WP_000120838.1|1291775_1292417_-|amino-acid-ABC-transporter-permease
MSYLFEILPSLLSGASMTLQVFALVLIFSIPLGVLIAFALQVHWKPLHHLINIYIWIMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEIFRGGIDTIPKGQYEAAKVLKFNSFDTVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVYALGISDLILASRTAANRDASLVPMFLVGAIYLILIGIVTILAKKVEKKYSYYR
>NC_013853.1|WP_000891752.1|1291136_1291766_-|amino-acid-ABC-transporter-ATP-binding-protein
MLELRNINKGFGEKQILSNFSLKIPEKQILAIVGPSGGGKTTLLRMLAGLETIDSGQIFYNGESLELDELEKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKTMGMKQEEAEKKARGLLEQLGLAGHADAYPFSLSGGQKQRVALARAMMIDPEIIGYDEPTSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADQILKVEPK
>NC_013853.1|WP_000182488.1|1290287_1291127_-|amino-acid-ABC-transporter-substrate-binding-protein
MTNKKIALVLVSLLTLFLTACTQKASDPKQDNWDKYQEQGTITIGFDNTFVPMGFEEKNGQYTGFDIDLAQAVSEKLGFKVQFQPIDWDMKETELQNGTIDAIWNGYSATDERREKVAFSIPYMENQQVLVTKKSQWIHSVEDMKDKTLGAQAGSSGYLDFEAQPDLLKNHVKDQKANQYQSFNEALIDLKNDRIDALLIDRVYANYYLQSEGILNDYNVFSAGFESESFAVGVRPADKRLLQALNQAFIALHQEGKFQEISQKWFGEDVATKEVKSRD
>NC_013853.1|WP_000102471.1|1288735_1290226_+|lysine--tRNA-ligase
MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQELKNKYADFDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEENYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETIYRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFITHHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVEAIKEITGVDFWQDMTFEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVSPLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATGIDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK
>NC_013853.1|WP_000780836.1|1287879_1288497_+|histidine-phosphatase-family-protein
MKLYFVRHGRTVWNQEGRFQGASGDSPLLPESIETLKRLGQYLKDVPFNQIYSSDLPRAVKSAEIIQSQLQTPCPLESVPNLREWQLGKLEGLKIATLEAIYPQQIKAFRSNLAKFDTQMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTASLRTLLGYKEPLLRKDGGLANASLTILETHDFETFTLDTWNDTSYQ
>NC_013853.1|WP_001085921.1|1287397_1287883_+|aminoacyl-tRNA-deacylase
MAKKVKVKKTLVEQILSKAGIPHQGIQINALEGELPQGYERDQIFKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANNPVGIRQKHNYPIFIDKLALELDQMIVSAGEVGHSIIVAPQDLANFVKADFADILEGSQE
>NC_013853.1|WP_000954113.1|1286555_1287398_+|DUF368-domain-containing-protein
MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAHPFKDFKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLKESTRESDRDKIDLAWFWTTFIISGLGLYALNFIVGTLNANFLNFVLAGALLALGVLVPGLSPSNLLLILGLYAPMLAGFKTFDLLGTFFPIGIGAGATLIIFSKLMDYALNNYHSRVYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLEDKYK
>NC_013853.1|WP_000163007.1|1297446_1298613_-|IS30-family-transposase
MTKKQKHLTLEDRIDIQTGISQQETFRSIAEKMGKDPSTISKEIKRNRIMHPTSVKSDCTDCPLLKKAPYVCNNCPKKRTDCGFNRYLYYAKKAQEQYETMLRESRQGIPLNKESFYQMDKVLTLGIQKKQSIYHIIQTHNLPVSKATVYRHAKLGYLTAKPIDFPRMVTFKERRKSRKVAIPKELKIGRTYQDFQELRETDDFFKWLEMDTVIGRPGGKLLLTFNVSFCNFLFALLLDNKTALEVATKFAALKERVMDGGYAFHQLFPVILTDNGSEFAYVEELERDIDGKSHLYFCDPSRPDQKGRIEKNHTVLRAILPKGTSFDQLTQKDVNLVISHVNSLKREEFQGKSAYDVFTFTFGEDIAALLGCQFVKPEDTHLSPDLLK
>NC_013853.1|WP_000665633.1|1298814_1299828_+|lactonase-family-protein
MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFATEPSPTYLAFDQHQHLYTVGSQDDKGGIAAYQTNGNLLNHVVEEGAPHCYVAVDEKRDLVYAANYHKGQVLVYKRQEDGRLLLSDVDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQVITYDLDSEGKLSKLYTYHSQPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGEFERMQVISTLPDGYEGFNGTAAIRLSKDGKYLYASNRGHDSIVVYTILADGSLELLEIVPTHGQTPRDFDLTPDQEFVIAVHQDSDNATVFKRNSETGRLAELSNDFHVPEAVCISFAP
>NC_013853.1|WP_125393602.1|1299932_1300532_+|transposase
MKSDQTIIRKNHMEQLHFITKLLDIKDLNIQIMNQFHRKSHEYKAIKRYWKLIQQDSRKISDKRFYHPTFRMHLTNKEILDKLLGYSKDLKHHYHLYQLLLFHFQDKKPDKFFGLIEDNLQQVHPLFQTVFKTFLKDKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTNFVLSRA
>NC_013853.1|WP_000527121.1|1300610_1308035_-|YSIRK-signal-domain/LPXTG-anchor-domain-surface-protein
MGNKPSMSRSERLRREKVTRYSIRKYSFGAASVAVAALFMFLGNGAVSVQADEIQEPKTADVPTKEVVLDKTQLKSYIAEIEEKISAGKYANKTEESIALLNSELASAKSVLASATSQDELKAAYNKFVTVVSSKLQNKPVEKKETPVVDTTNGKETVGKKAENTEKKSDSNSIENTGSNDSRNGKALDRDNAFRTEAVTNKKPVGNIPFSNATAKDIYVYKGEETNIELSATDDSGKLKDIRIAEGSRGIDAAGAAGGRINNQYGLTFSSQRNETEGIVATQDNPAKVTITGTVSVPNRPTYTGKLVTRYLVAEDLDGAVFSEPSGNQENANPLPEGYFKLWVREQTQKYDIQVQTNEAGKIAVADVNNLSQADFEKIKNNIKITYNTADDARLLDKNGKLVENASNYIDTVTKQADQIVVTYKDGSRDSVALTSVLRNNPIPTVKVPYSNQAEKQVYVYKGENTDLTFTANDDTTVKDMYLRGPGDVNWNNTEAFGFTTGKIDNGVVTGKGTISDNKQEATITMTGETNLDAGKQWTSYVVANDNDNFSSMPADRNFNALDIDPDAKSKPGYIRFVVKDQTSKYDIKDLTDSTRITVNDIDNITATDLATIKSRLKLEYSSTNDDERLASLKGTAVTNPTSLIDTVAVSTTDPSKLVVTYKDGSVDTIEKSKVLNVRPKGIIPFSNPATKEIYVYKGEETNIELSATDDSGKIKDIRIAEGGRGNDAPGAAGGRIRDQYGLTTGYQRNETGIEATETNPAKVTITGTVSVSGQPNFKGNLMTRYLVAEDLEGATFSDPNGNSDSGKTVDQVPEGWFKLVVREQTQKYDIQGQTEEANKIAVSDINNLSNDDFEKIKNNIKIQYNTADDERLKDKNGSLVENASQYIKSITKEGDKIVVTYKDGSTDKLTLTEVVKLDKQPAIDAVNTAATEKIAAINSTPNATDEEKAAAIAKVNADKEKALTAINDANVTTKAELDKAKEAGTTAIAGDNPVVAKKAAAKADVEAARQAKADAINADKNLTQAEKDAALAKVNKAAEDATKAIDAATTDAAVDTAKGTGVTEIGKVNPVAKQNAKDAIGNALTAKNQEIDDRKDLTQAEKDAAKAEAKKLADAELTKVNAQPDNAETAEAAAAAQKLVNDAEDKGVADVTSVYPIAKEEAKKAVADELAKKEKELDDRKDLTTEEKAAAKKEAKDLAKKATDAINAQPAIADTSDKATAAQQAVDTAKTTGVAEVKAVNPEAVKKNVAKKAIEDALTAKNNAIDARDDLTPEQKTAAKEAAKAKADAAKDAIDKATTDADVDQAKTDGETAVANVTPVAKKPAKQAIAKALEDKNAEIDKRTDLTEEEKATAKKEAKDKADAQLAEIAKQPDVADTPEAAQTAQTAVDAAKKTGVDEVTAVNPTAVTKPEAKKAIDAKLAEQLKTIESTPDATDDEKKVAADAAKALAAKAKAEIDKAGTDADVKALEDEAKAEIEKSLPLVEDKPNARKAIDEEATAKKAAIDSRTDLTPKAKEDLKAQVDKIAEQAKKSVDAAKTAEAVDGIEESDKAAIKAVGEVNIPADKVLVNDPSTLTDDEKAKVLEAVKKVNPDAKEITQDADGNITVTTPDGHQETITPEQVVKTSDTANEPKAGNDVVKPANKVVVADPAKLTDAEKEKIKAAVEAVNPNSVVTVDEKGNAKVSTPDGQTQVIPVDELVRTAEDTKKPNAGNDINTPSDKTVVANPEALTPEEKKAIEDKVKAVNPGATVVVDDKGNATVTTPSGKTAVIPAADLTKTAEAAAKPNAGDDVVKPASKTVVANPEALTPEEKKAIEDKVKAVNPGATVVVDDKGNATVTTPSGKTAVIPAADLTKTAEAATKPNAGDDVVKPASKTVVANPEALTPEEKKAIEDKVKAVNPGATVVVDDKGNATVTTPSGKTAVIPAADLTKTAEAASKPNAGDDVITPASKTVVANPEALTPEEKKAIEDKVKAVNPGATVVVDDKGNATVTTPSGKTAVIPAADLTKTAEAATKPNAGDDVVKPASKTVVANPEALTPEEKKAIEDKVKAVNPGATVVVDDKGNATVTTPSGKTAVIPAADLTKTAEAVAKPNAGNDINTPAVKTAVAKKDALTDSEKEAVKTAVEAVNPGAKVVVDDKGNATVTTKDGKTAVIPASQLVIPTEKLADLSEQNGVNIPATRTLVADKNNLTPEEIAKIKVAVEAVNPGSTVVVDEKGNATVTTVDGKTATISAEQLVKDEADVATKNNGENLNLDFEKQLVADLDNLTDADKAGAKAKIMAANPDVAEVIFDDKGNATVILNNGKAYTVLAKDIFKEIPYVPSYNRGNNRINNAETIVDKSKLEGAIRQLDKLIIQESAKLDAETVKEANALLAAAKEVFANANATQAEVDAMVKRIEDFMLKVSPATNHAILANDQATQATNANQETANVNTVAKELPNTGTEANASLAALGLLGALGGFGLLSRKKKED
>NC_013853.1|WP_000068046.1|1309147_1309567_-|F0F1-ATP-synthase-subunit-epsilon
MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAVLAVDEVKVKRIDDEEHVNWIAVNGGVIEIANDTITIVADSAERARDIDISRAERAKLRAEREIEEAQDKHLIDQERRAKIALQRAINRINVGNRL
>NC_013853.1|WP_000094352.1|1309577_1310984_-|F0F1-ATP-synthase-subunit-beta
MSSGKIAQVIGPVVDVLFAAGEELPEINNALVVYKNDERKTKIVLEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDLEAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQLGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDEEKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKHDHLPEDAFRGVGSIEDVIAKAEKMGF
>NC_013853.1|WP_000301214.1|1311069_1311948_-|F0F1-ATP-synthase-subunit-gamma
MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQVYAQKVRKLLTDILHGNGAGGSTNPMLISRPVKKTGYIVITSDRGLVGGYNSSILKAVMELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDEVRKIISKTVEMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADDSYSLTFELETSREEILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAAITQEITEIVAGASALE
>NC_013853.1|WP_000996630.1|1311963_1313469_-|F0F1-ATP-synthase-subunit-alpha
MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGLENAMSGELLIFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGESLIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIGRGQRELIIGDRQTGKTTIAIDTILNQKGQDMICIYVAIGQKESTVRTQVETLRQYGALDYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLLLRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNVISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYRELEAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPVDDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEEVLDAAITEFLNQTSFQ
>NC_013853.1|WP_000359027.1|1313483_1314020_-|F0F1-ATP-synthase-subunit-delta
MDKKTVKVIEKYSMPFVQLVLEKGEEDHIFSDLAQIKQVAEETGLPSFLKKVAVDESDKEKIIAFFQDSVSPLLQNLIQVLIYNHRANLFYDVLVDCLNRLEKETNRFEVTITSAHPLTDEQKSRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHKTIDVSIKQQLKVVKENLK
>NC_013853.1|WP_000558549.1|1314019_1314514_-|F0F1-ATP-synthase-subunit-B
MHVTVGELIGNFILIAGSFILLLVLIKKFAWSNITGIFEERAEKIASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEKSKASILADAKLEAGRLKEKANQEIAQNKAEALQSVKGEVADLTISLAGKIISQNLDGHAHKELIDQYIDQLGEA

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Crispr_ID: NC_013853_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013853_3

2038341-2038436

Orphan

Consensus_repeat	Method
TTATATATAAAAATTTTACACATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_013853_3

>merge|NC_013853|3|2038341-2038436|CRISPRCasFinder
TTATATATAAAAATTTTACACATTCCTCTTGACAGGGCTTTCTTTTAGATGTACAATGTATGTGTAGAAAAATTATATATAAAAATCTTACACATT

>NC_013853|3|3|2038341-2038436|CRISPRCasFinder
TTATATATAAAAATTTTACACATT	CCTCTTGACAGGGCTTTCTTTTAGATGTACAATGTATGTGTAGAAAAA
TTATATATAAAAATCTTACACATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_013853.1\|WP_000890771.1\|2036163_2036994_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133038
NC_013853.1\|WP_001268145.1\|2029985_2030849_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_013853.1\|WP_001229052.1\|2039352_2040264_+\|DUF4097-family-beta-strand-repeat-protein	unknown	unknown	gnl\|CDD\|372574
NC_013853.1\|WP_000808422.1\|2040321_2041386_+\|hypothetical-protein	unknown	unknown	unknown
NC_013853.1\|WP_001030020.1\|2042544_2043531_-\|rhodanese-related-sulfurtransferase	unknown	unknown	gnl\|CDD\|234663
NC_013853.1\|WP_000744880.1\|2037148_2038315_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340897
NC_013853.1\|WP_000167728.1\|2041455_2042316_-\|DUF4299-domain-containing-protein	unknown	unknown	gnl\|CDD\|339103
NC_013853.1\|WP_000818352.1\|2046791_2047715_-\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NC_013853.1\|WP_001035710.1\|2034074_2035925_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NC_013853.1\|WP_000200879.1\|2033335_2033968_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319798
NC_013853.1\|WP_000843471.1\|2030900_2031521_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|212030
NC_013853.1\|WP_000500045.1\|2032441_2033314_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NC_013853.1\|WP_000188113.1\|2043662_2043959_-\|bacteriocin-immunity-protein	unknown	unknown	gnl\|CDD\|370205
NC_013853.1\|WP_000800385.1\|2045053_2046535_-\|DUF3502-domain-containing-protein	unknown	unknown	gnl\|CDD\|378792
NC_013853.1\|WP_000385029.1\|2028190_2028982_-\|hypothetical-protein	unknown	unknown	unknown
NC_013853.1\|WP_000838911.1\|2031761_2032433_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
NC_013853.1\|WP_000732158.1\|2029055_2029457_-\|hypothetical-protein	unknown	unknown	unknown
NC_013853.1\|WP_000760537.1\|2044026_2044716_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NC_013853.1\|WP_000198700.1\|2038766_2039360_+\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|227053
NC_013853.1\|WP_000273857.1\|2038453_2038780_+\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609

Protein	Function_ID	Function_description	E-value
NC_013853.1\|WP_000890771.1\|2036163_2036994_-\|glycosyltransferase	gnl\|CDD\|133038	cd04195, GT2_AmsE_like, GT2_AmsE_like is involved in exopolysaccharide amylovora biosynthesis. AmsE is a glycosyltransferase involved in exopolysaccharide amylovora biosynthesis in Erwinia amylovora. Amylovara is one of the three exopolysaccharide produced by E. amylovora. Amylovara-deficient mutants are non-pathogenic. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.	3.16207e-85
NC_013853.1\|WP_001268145.1\|2029985_2030849_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.18538e-10
NC_013853.1\|WP_000760537.1\|2044026_2044716_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	8.25738e-10
NC_013853.1\|WP_001030020.1\|2042544_2043531_-\|rhodanese-related-sulfurtransferase	gnl\|CDD\|234663	PRK00142, PRK00142, rhodanese-related sulfurtransferase.	0
NC_013853.1\|WP_000744880.1\|2037148_2038315_+\|MFS-transporter	gnl\|CDD\|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.0539e-122
NC_013853.1\|WP_000167728.1\|2041455_2042316_-\|DUF4299-domain-containing-protein	gnl\|CDD\|339103	pfam14132, DUF4299, Domain of unknown function (DUF4299). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 275 and 313 amino acids in length. There are two conserved sequence motifs: RGF and DAY. There are two completely conserved residues (P and D) that may be functionally important.	2.00904e-114
NC_013853.1\|WP_000818352.1\|2046791_2047715_-\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	8.95789e-69
NC_013853.1\|WP_001035710.1\|2034074_2035925_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NC_013853.1\|WP_000200879.1\|2033335_2033968_+\|HAD-family-hydrolase	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.80329e-95
NC_013853.1\|WP_000843471.1\|2030900_2031521_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	1.04374e-14
NC_013853.1\|WP_000500045.1\|2032441_2033314_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.68262e-105
NC_013853.1\|WP_000188113.1\|2043662_2043959_-\|bacteriocin-immunity-protein	gnl\|CDD\|370205	pfam08951, EntA_Immun, Enterocin A Immunity. Gram-positive lactobacilli produce bacteriocins to kill closely-related competitor species. To protect themselves from the bacteriocidal activity of this molecule they co-express an immunity protein (for discussion of this operon see Bacteriocin_IIc pfam10439). The immunity protein structure is a soluble, cytoplasmic, antiparallel four alpha-helical globular bundle with a fifth, more flexible and more divergent C-terminal helical hair-pin. The C-terminal hair-pin recognizes the C-terminus of the producer bacteriocin and this interaction is sufficient to dis-orient the bacteriocin within the membrane and close up the permeabilising pore that on its own the bacteriocin creates. These immunity proteins interact in the same way with other bacteriocins, family Bacteriocin_II, pfam01721. Since many enterococci can produce more than one bacteriocin it seems likely that the whole operon can be carried on transferable plasmids.	0.000606963
NC_013853.1\|WP_000800385.1\|2045053_2046535_-\|DUF3502-domain-containing-protein	gnl\|CDD\|378792	pfam12010, DUF3502, Domain of unknown function (DUF3502). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 140 amino acids in length. This domain is found associated with pfam01547.	2.13058e-44
NC_013853.1\|WP_000838911.1\|2031761_2032433_+\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	9.55474e-90
NC_013853.1\|WP_001229052.1\|2039352_2040264_+\|DUF4097-family-beta-strand-repeat-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	1.0718e-27
NC_013853.1\|WP_000198700.1\|2038766_2039360_+\|DUF1700-domain-containing-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	1.00038e-62
NC_013853.1\|WP_000273857.1\|2038453_2038780_+\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.12912e-19

>NC_013853.1|WP_000744880.1|2037148_2038315_+|MFS-transporter
MKKQSLFFVPGIILIGVSLRTPFTVLPIILGDISQGLGVEVSSLGVLTSLPLLMFTLFSLFSTRLAQKIGLEHFFTYSLFFLTIGSLIRLINLPLLYLGTLMVGASIAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGLILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQTKVMHNKQVWAVIVFAGFQSLLFYTAMTWLPTMAIHAGLSSHEAGLLTSIFSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGMVGISMLFFPVGNFFYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLVDIIMTVALFTVDRADKIL
>NC_013853.1|WP_000890771.1|2036163_2036994_-|glycosyltransferase
MLEKQKISVLMSVYVKENPTFLRDAINSIQNQTLKPSELVLVEDGPLTPELYQVLDQVEAESNIPVKRCPLEENQGLGLALRYGVLQCQYDIIARMDTDDIAVPDRFEKQVQLMEKDHLDLLGGHIAEFIDNPDEIVSYRRVPTQHADIVAYQRMRSAFNHMTVMFKKDMVLKAGNYEDGLYMEDDLLWLNMIATGAKTGNLDQILCQVRVGAGMFERRGGLRYLKLYRQARQRMLKRGQISYMEYAKSVAIQMVVALCPGFVRQFIFMKLLRKSK
>NC_013853.1|WP_001035710.1|2034074_2035925_-|polysaccharide-biosynthesis-protein
MNKKLTDYVIDLVEILNKQQKQVFWGIFDILSMVVSIIVSYILFYGLINPAPVDYIIYTSLAFLFYQLMIAFWGLNASISRYSKITDFMKIFFGVTASSVLSYSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGAGDGGALFMDSYQHPTSDLELVGILDKDAKKKGQKLGGIPVLGSYDNLPELAKRHQIERVIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAATGFQKIDITDLLGRQEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVYHELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIIEVGIRAGEKLYEELLVSTELVDNQVMDKIFVGKVNVMPLEAIDQKIEEFRTLSGDELKQAIIAFANQTTHVE
>NC_013853.1|WP_000200879.1|2033335_2033968_+|HAD-family-hydrolase
MTSITAIFFDLDGTLVDSSIGIHNAFTHTFKELGVPSPDAKTIRGFMGPPLESSFATCLPKDQISEAVQIYRSYYKEKGIHEAQLFPQIVDLLGELSSSYPLYITTTKNTPTAQDMTKNLGINHFFDGIYGSSPETPHKADVIRQALQTHQLAPEQAIIIGDTKFDMLGAQETGIQKLAVTWGFGEQADLLNYQPDYIAHKPIEVLEYFQ
>NC_013853.1|WP_000500045.1|2032441_2033314_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVLLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDRYIKNGKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
>NC_013853.1|WP_000838911.1|2031761_2032433_+|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPTEVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKDSNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDIPGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIDEIRKIPHLHNVNFFK
>NC_013853.1|WP_000843471.1|2030900_2031521_-|LysM-peptidoglycan-binding-domain-containing-protein
MKSTTKKIKTTLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLSEIAETHNTTVEKLAENNHIDNVHMIYVGQELVIDGPAAPVAPASTTYEAPAAQDEAVSATVAETIEVEEETPAASGTVAEETVATTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY
>NC_013853.1|WP_001268145.1|2029985_2030849_+|helix-turn-helix-transcriptional-regulator
MRYDFGKVYKEIRESKGLTQEEVCGEVLSRTSLSKIESGKATPKYENMEFLLRQINMSFEEFDYICHLYHPSQRTEIMQTYLNMSSTLGTSELEKLFQKCQDYLKTHHDLPIEEIRDMLEIVIHIRQHGTEQLSDQVKQTIKKLWEKIEKQDTWYENDLKILNTILFSFPIEHLHLITGKILQRLEVYKNYQHLYDLRMAILLNLSTIYLYHQDKNMCQQICYTLLEDAKKKKHYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYSQPKEI
>NC_013853.1|WP_000732158.1|2029055_2029457_-|hypothetical-protein
MKKLDTKTKLFASICATLMIGAMAVSAREISDYDMIMPRFGGRTVTDSLYKTNQSRGVNNNTSIGGGYTMHCAIFRGDAQMTRTYSAGSGDRIYLNYNSPSDAEGANLRLGGWTGFATYVKVQTSGSWSPDEY
>NC_013853.1|WP_000385029.1|2028190_2028982_-|hypothetical-protein
MDYKVSMFLKGMKNKQFFLAILIILTSMIFSVSAFIEEGMEYFFNHDYIVAFLQGYNGDRSLLIVLAPLIATIPFASQHIENRKSGIMKYIISRMGYKQYFNSIFIINGFISFTTFIFGMLLFLIMSILFFNRSINMDAYYAITKVSIYESAVRTSPLFYVVIIILHCSFVGVAYSSVGLAMSYFIKSKFVAWLSPFILTTIGSLFAMFLGLTKIEPMAIFDVSRVKGISIIFVFVYLILVVVISYWMSYKKFKRDIETDEEI
>NC_013853.1|WP_000273857.1|2038453_2038780_+|PadR-family-transcriptional-regulator
MYFPTSSALIEFLILAVLEQDDSYGYEISQTIKLIANIKESTLYPILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGSIRHDKN
>NC_013853.1|WP_000198700.1|2038766_2039360_+|DUF1700-domain-containing-protein
MTRTEYLTQLELYLKKLPQADQIEAMDYFRELFDDAGVEGEEELIASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILVSLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGASSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGDQHA
>NC_013853.1|WP_001229052.1|2039352_2040264_+|DUF4097-family-beta-strand-repeat-protein
MRKLTKGFLIFGVVTTIIGFILLFVGIQSDGIKSLLAMSKEPVYDSRMEELTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDKTLTLTDKKLSETPFLSSGIGGILHIASSYSRRFEEVILQVPKGRSLKGINVSANRGQTTIINASLENATLNTNGYLLRIEGSRIKNSKFKTPNIINILDTDLTDSQLESTKNHFYVDNIKVYGKVELTSKKELSIKLTQKESQEINLDLSSHYGPIYQLSRDESQHHPNELSNPYKTEKTDVKGQLIARAEDYISLETTANKP
>NC_013853.1|WP_000808422.1|2040321_2041386_+|hypothetical-protein
MKQEWFESNDFVKTSSKNKPDEQAQDGADKAEETIPDLDTPIEKNTQLEKEVSQAEAELESQQEEKIETPEDSEAKTETEEKKALDSTEEEPDLSKETEKVTKAEENQEALSQQKTTTKEPLLLSKSLESPYIPDQAQKSTDRWKEQVLDFWSWLVEALKSPTSKLETSSTHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIATINSHFPEQFASLNLFSIISILVATTLFFFSFLLGSFVVRRFIYQEKDWTLEKVLQQYSQLLAIPIFLTAIASFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIILLFFVAEVALIGDYLRILAFL
>NC_013853.1|WP_000167728.1|2041455_2042316_-|DUF4299-domain-containing-protein
MTKTFFIPNKQSILGEQEILTAKSILTLVDGLESHSYDAVYLRQPLNRLEYIECAIVGQSQFLFKVSYVDGQKAYRVDLPDLLTKTDWQIIKAFLDALLAYTGTEIEGLNSFDFEAYFQASIQAYLADTATRFTICQGIFNPVFFSHEDLKSFLEEDGLAQFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPVAYIEQLLDKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPSASYHQLDANQLEVQPILDKDFKALAQEK
>NC_013853.1|WP_001030020.1|2042544_2043531_-|rhodanese-related-sulfurtransferase
MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDEDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSEHELTQAEVVERLAAIGESLDQAATV
>NC_013853.1|WP_000188113.1|2043662_2043959_-|bacteriocin-immunity-protein
MTPLKWFAGGSERRCEAMTIINHLLEGINNTPQLTPLKNLLVSYKRRLEDDGTSTPFILSQMNVDISHVLIDNKLILSESQAEQIKKLRELSAIRYGY
>NC_013853.1|WP_000760537.1|2044026_2044716_-|CPBP-family-intramembrane-metalloprotease
MKKYQLLFKISAVFSYLFFVFGLSQMTLIVQNYWQFSSQIGNFVWIQNLLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKHVQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDLLLPSILFALPHFSSLPSLLDIFVFAISGIIFASLTRYTKSIYPSYAVHVINNIFATLPFLLTFLHRVFG
>NC_013853.1|WP_000800385.1|2045053_2046535_-|DUF3502-domain-containing-protein
MKNWKKYAFASASVVALAAGLAACGNLSGNKKAADSASGEKTVIKMYQIGDKPDNLDELLENANKIIGEKVGAKLDIQYLGWGDYDKKMSVITSSGENYDIAFASNYVVNAQKGAYADLTDLYKKEGAELYKALDPAYIKGNSINGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAVTKNFIPSDNFDYPVPNGLPFVIDLEGDTTKIVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEVLNLLNTNPELLNGLVYGPEGKNWEKIAGKENRVKVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIEDSKKQLAEAKESPALGFIFNTDNVKSEISAISNTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYDKVLNEMQKQYDEFLKNKKS
>NC_013853.1|WP_000818352.1|2046791_2047715_-|carbohydrate-ABC-transporter-permease
MAEKKIKKEKIDNVGIHSFSKKADIFFSTISGLIALSCILPFVFVIVISVTDEKSILQNGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNVFITTTYAYAISRTTFKYRRFFTIFALLSMLFNAGLVPGYIVVTRLLQLGDTVWALIVPMLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTALGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLSGQLGVALPKETGRMAMVVVATLPIAILYPFFQRYFVKGLTIGGVKE

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Crispr_ID: NC_013853_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013853_4

2065610-2065688

Orphan

Consensus_repeat	Method
TGGAATTTACTTAGAAAATAAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_013853_4

>merge|NC_013853|4|2065610-2065688|CRISPRCasFinder
TGGAATTTACTTAGAAAATAAAAAATAGTTGATTTAACAACGTTTTTAGCCTACTTGGAATTTACTTGGAAAATAAAAA

>NC_013853|4|4|2065610-2065688|CRISPRCasFinder
TGGAATTTACTTAGAAAATAAAAA	ATAGTTGATTTAACAACGTTTTTAGCCTACT
TGGAATTTACTTGGAAAATAAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_013853.1\|WP_004235732.1\|2076420_2077305_-\|SPFH-domain-containing-protein	unknown	unknown	gnl\|CDD\|259805
NC_013853.1\|WP_001003769.1\|2062816_2063032_-\|hypothetical-protein	unknown	unknown	unknown
NC_013853.1\|WP_000058836.1\|2062204_2062546_-\|hypothetical-protein	unknown	unknown	unknown
NC_013853.1\|WP_164925535.1\|2072446_2073748_-\|Ig-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|336728
NC_013853.1\|WP_000382047.1\|2063230_2063662_-\|hypothetical-protein	unknown	unknown	unknown
NC_013853.1\|WP_000122741.1\|2062526_2062820_-\|hypothetical-protein	unknown	unknown	unknown
NC_013853.1\|WP_001269498.1\|2081353_2082058_-\|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224046
NC_013853.1\|WP_000040968.1\|2064737_2064938_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
NC_013853.1\|WP_165442198.1\|2061797_2061944_-\|hypothetical-protein	unknown	unknown	unknown
NC_013853.1\|WP_000724053.1\|2079039_2080545_-\|zinc-ABC-transporter-substrate-binding-lipoprotein-AdcA	unknown	unknown	gnl\|CDD\|238499
NC_013853.1\|WP_000171240.1\|2063033_2063234_-\|hypothetical-protein	unknown	unknown	unknown
NC_013853.1\|WP_000492147.1\|2061936_2062212_-\|hypothetical-protein	unknown	unknown	unknown
NC_013853.1\|WP_012972621.1\|2073771_2076237_-\|DUF4982-domain-containing-protein	unknown	unknown	gnl\|CDD\|225789
NC_013853.1\|WP_000704662.1\|2067274_2068441_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NC_013853.1\|WP_000251209.1\|2070762_2072445_-\|alpha-L-fucosidase	unknown	unknown	gnl\|CDD\|226195
NC_013853.1\|WP_000424672.1\|2064096_2064723_-\|Rha-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226172
NC_013853.1\|WP_000950038.1\|2080554_2081361_-\|metal-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|334323
NC_013853.1\|WP_001080846.1\|2065143_2065569_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_013853.1\|WP_000431494.1\|2065690_2067157_+\|putative-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|225420
NC_013853.1\|WP_000803428.1\|2068632_2070717_+\|GH92-family-glycosyl-hydrolase	unknown	unknown	gnl\|CDD\|226067

Protein	Function_ID	Function_description	E-value
NC_013853.1\|WP_004235732.1\|2076420_2077305_-\|SPFH-domain-containing-protein	gnl\|CDD\|259805	cd03407, SPFH_like_u4, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes an uncharacterized family of proteins similar to stomatin, prohibitin, flotillin, HflK/C (SPFH) and podocin. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Many superfamily members are associated with lipid rafts. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Microdomains formed from flotillin proteins may in addition be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and are known to interact with a variety of proteins. Stomatin interacts with and regulates members of the degenerin/epithelia Na+ channel family in mechanosensory cells of Caenorhabditis elegans and vertebrate neurons and participates in trafficking of Glut1 glucose transporters. Prohibitin may act as a chaperone for the stabilization of mitochondrial proteins. Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection. Flotillins have been implicated in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease and, in cancer invasion and metastasis. Mutations in the podocin gene give rise to autosomal recessive steroid resistant nephritic syndrome.	4.88018e-133
NC_013853.1\|WP_164925535.1\|2072446_2073748_-\|Ig-like-domain-containing-protein	gnl\|CDD\|336728	pfam07532, Big_4, Bacterial Ig-like domain (group 4). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in a variety of bacterial surface proteins.	3.13161e-07
NC_013853.1\|WP_000040968.1\|2064737_2064938_-\|transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	4.99339e-08
NC_013853.1\|WP_000424672.1\|2064096_2064723_-\|Rha-family-transcriptional-regulator	gnl\|CDD\|226172	COG3646, COG3646, Uncharacterized phage-encoded protein [Function unknown].	6.54567e-40
NC_013853.1\|WP_001080846.1\|2065143_2065569_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.10748e-17
NC_013853.1\|WP_000724053.1\|2079039_2080545_-\|zinc-ABC-transporter-substrate-binding-lipoprotein-AdcA	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	2.94812e-132
NC_013853.1\|WP_001269498.1\|2081353_2082058_-\|metal-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	3.43904e-109
NC_013853.1\|WP_000704662.1\|2067274_2068441_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	9.81101e-46
NC_013853.1\|WP_000431494.1\|2065690_2067157_+\|putative-DNA-binding-domain-containing-protein	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	9.77234e-65
NC_013853.1\|WP_000251209.1\|2070762_2072445_-\|alpha-L-fucosidase	gnl\|CDD\|226195	COG3669, COG3669, Alpha-L-fucosidase [Carbohydrate transport and metabolism].	6.85818e-164
NC_013853.1\|WP_000950038.1\|2080554_2081361_-\|metal-ABC-transporter-permease	gnl\|CDD\|334323	pfam00950, ABC-3, ABC 3 transport family.	5.74168e-73
NC_013853.1\|WP_012972621.1\|2073771_2076237_-\|DUF4982-domain-containing-protein	gnl\|CDD\|225789	COG3250, LacZ, Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].	4.69012e-101
NC_013853.1\|WP_000803428.1\|2068632_2070717_+\|GH92-family-glycosyl-hydrolase	gnl\|CDD\|226067	COG3537, COG3537, Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism].	0

>NC_013853.1|WP_001080846.1|2065143_2065569_+|helix-turn-helix-transcriptional-regulator
MNRLKELRQEKKLSQKELAENIGVHYRTLQNWENGESQIKPEKAQQLADFFGVSVGYLLGYEEAKTLENILKDAEEYLEMTEDDLLSDNYSSRIKIALSEMSDIPVLKNEIIYNLDFLSYDNLKAICQIVNELPKKEKYDL
>NC_013853.1|WP_000040968.1|2064737_2064938_-|transcriptional-regulator
MSKLRGYRVMLGLTQQQMADKLKISLQSYNNKELGKTPFNDKERLAIKSMVAEIRSDITIDELFYS
>NC_013853.1|WP_000424672.1|2064096_2064723_-|Rha-family-transcriptional-regulator
MELVYMDGKKEPYTLSSIVAECTGLQHHTITKTIRRHQARFEQFGKVGFKIQAMESGQNTKDYILNEQQATLLVTFLKNTEQVANFKTNLVKAFFEMRDELSKFRMQRALEKPKRKTLHDSIENWEAKPKHAHSTMNNLLLKAVTDRNAKQLREERGGYNGIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA
>NC_013853.1|WP_000382047.1|2063230_2063662_-|hypothetical-protein
MDTYFKDFETELGLVEEKLDILSEWHLSKKHHGATEIAEDCRSAISQLWIQFYKLSETYKKQEASHEEFFNRNVENLLGELKKYDDDCTERHGEAPDWLLFNFLDQAIKENNLSNGINHTTTSTWMYLRRLVVADLEERGLLK
>NC_013853.1|WP_000171240.1|2063033_2063234_-|hypothetical-protein
MTLDLDNMTQAEFDEVMAEIKSRNPNLFQFIADFLDRKVTPEEVDDFLKMERTEQVDYIKNYQARA
>NC_013853.1|WP_001003769.1|2062816_2063032_-|hypothetical-protein
MNELDLTNTQAVIFMVVLIGLLLYLNHRDRKKSAQFERENQQTIETPSEDLNPEYGRYIQLAGVRVYGGMK
>NC_013853.1|WP_000122741.1|2062526_2062820_-|hypothetical-protein
MSYTVKIYPDIEKIPDEPYFTKDIFLATCMDNATKLAVTMGLLTKQTLDLETKTAILKTLDTIIETQKDILRGVTSGQITFLNKSKEEEELNESIRE
>NC_013853.1|WP_000058836.1|2062204_2062546_-|hypothetical-protein
MSLSENDKRVLRLIKVGAENSITGAEISLLTKLAERTVQDIISRLITRHSVPIVGVRHGTFRGYFIPANKEELLDGAKTFYNQIREEEKRLAVLMNSDLESYKETLKEVGGYV
>NC_013853.1|WP_000492147.1|2061936_2062212_-|hypothetical-protein
MFSLSRESEQDLVHGILEVVERYHEARDKLKPRLTGLISAQEVMDELDIKYMTLQKWEKAGLRRYHPPLEDTRKVYYKITDIWKFLGVENG
>NC_013853.1|WP_165442198.1|2061797_2061944_-|hypothetical-protein
MGRYNTHPAQGGGHYHDIKLYKHRGRSLEQFQEQKLLKKLKKKRKKGR
>NC_013853.1|WP_000431494.1|2065690_2067157_+|putative-DNA-binding-domain-containing-protein
MENRDSEKLLKLLTKNEDEIIEYKVNNNDHERIGKYISALANSSAILNRQFSYLIWGIDDDSKEIFGTKFYPKTEKHGGEPFITWLERMLDPRITIRFEEYDIDQNHVVVLVIHMNAGRPVAFKGDRYIRSGSSLKNLKDYPEKERELWKSFEARSFEKEYAKTACTFDEIKELLDVNSYLKMLGHFVGSTDEEIITHMINDGIVEPSGKSFNLTNMGAFTFAKNLKNFENLSSHALRVIRYDGNNKLSAVADNTASKGVAVGFDGLLKFINSHLPRKPETLKENGQITSDTDYPPLVIREIVANQIVHQDFSVKGSSPIIEIFDNRVVFTNPGSPLNRPERLLDMPPYSRNEDLANLFRKMHLVESRGSGIDKIILTLELNHLPAPDITAKDNYTVVTLHQRRTIQEMGNREKINAIYYHSAILYIEDDYMTNSTLRERFGLTNKQSSVASKLISLALENNKIKIYDENAGKKNMQYIPYWGIGYNE
>NC_013853.1|WP_000704662.1|2067274_2068441_+|site-specific-integrase
MKITEVIKKDGSKVYRANVYLGVDQVTGKKVKTKVTGRTQKEVKQKANQEKIAFQKAGSTRQKAITIRNYQELATLWWESYKNTVKPNTQGNVRALIDNHILPTFGEYKLDKLTTPLIQSIINKLADKANRGEEGAFLHYDMIHALNKRILQYGVTMQAIPSNPARDVVLPRNTQKAKRQKLKHFDNQELKKFLVYLDNLDSCKYRYYYDVTLYKFLLATGCRINEALALSWSDIDLDNAIVHVTKTLNQYLEINSPKSKSSYRDIDIDQETVSMLKQYKLRQTKEAWKIGQRESVVFSDFIHEYTSIVKLKKRLLTHFKRADVPNIGFHGFRHTHASLLLNSGIPYKELQHRLGHSQISMTMDTYSHLSKENAKKAVSFYETALKAL
>NC_013853.1|WP_000803428.1|2068632_2070717_+|GH92-family-glycosyl-hydrolase
MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSDQEGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPITGQLGGDSLFHRQSSYDIDKASFQPHYLKIFSLRYQIESQLTPTRYGASIRLEQKQGKALSLYLHAADELTIEQVDKRNLALRQEGKTETNKNPLILFTTLQMNTDIIAISQEGEDWRIDLADSHAEIQLATSFISPSQALLNLPQEDFDSCKSNAQADWENLLHRFDVIKTGEADRTFFDHCLYRLFLFPQTFYEVDESGQAIHIDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYHRFLEGFLNNYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEEELLQAMLETACKSDPLGINARHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCISSCAEKLGKIEIAETYKAASQNYRHLFDAETGYMRARDSQGNFRPDFSPYSWGRDYAECSAIQATLGVLHDIPDLIQLMGGKEAFSNYLLKTCQEAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYLFHYSNYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPSYDLGIPLFDHLRVYLAKEDKWLDIHTKQNHSHFNFVKECRLDNTSITSIQHQDLLKAEQLTFTLSWLPSH
>NC_013853.1|WP_000251209.1|2070762_2072445_-|alpha-L-fucosidase
MVREIKPHGPLPSQAQLAYLEDELAAFIHFGPNTFYDQEWGTGQEDSERFNPTRLDAREWVRVLKEMGFKKLILVVKHHDGFVLYPTAYTDYSVKASPWRNGEGDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDQEADYNAYYLAQLKEILSNPAYGNGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGYAGDPLWQKVNPDKLGTEAALDYLQHGDSSGTIFSIGEADVSIRPGWFYHEEQDPKSLEELVEIYFHSVGRGTPLLLNIPPNQDGLFDEKDIKRLYEFATYRNELYKEDLALGAKVYGPALSADFACHHLTDGLESSSWASDADLPIQLELDLGFPKTFDVIELREDLKLGQRIAAFHVQVEVDGVWQEFGTGFTVGHKRLLRGPLVEAQKVRVMITESQDLPVLTKISLYKTPSLSQKEVVQGLAFAEKSLSVAKGETLHFRIERSESNTPLEAKISIQPGTGVHGIAYQDEIQVLQFQAGESKKDLCLPTLHFAADKTLDFYLNLTVDGQLVDQLQVQVS
>NC_013853.1|WP_164925535.1|2072446_2073748_-|Ig-like-domain-containing-protein
MGEAFGCQPVKNQRLFEIRVDKQAGLQEGDSPAIGLYPQTVDNSVNKVGNSEVIWETSGGAHAIINQGVLHCLSAGDLAIRAMYQGKTYQTHLQVAENTSLGKAVSVRPLRLYTAKGTYPQLPSSVLVDYESGSAKRVKVVWEAISEEDIASFHTFTVSGQLEGLDLKASAQVCVQGICAIEPEKVWTLVKEAPHLPDRVKLVLSDGRRDKTKVIWTELDSQIYAQVGESVLTGQVAGCELPATVTIHVTDISVDGEVISNQWTGSNLPLVFASHSEPNHPASYLNDKVIVRKKSTANTWITKSEQASVGILFGDAGILKPRFVDNVTLYYVENQEYVAVDPTFIDYYIGNEPSLPRTPNHLDKDSLLKQEENWRPVSAIRKVSSDKSEELRFEFDKVETYALRLRFENLVNLLALTELQVHAKKVKKNVDRK
>NC_013853.1|WP_012972621.1|2073771_2076237_-|DUF4982-domain-containing-protein
MRREEVLRNYWFFSQEVGKEEALASDFQRENWQAIQVPHDWSIYNDFDQYSPAQNEGGQLNGGQAWYRTQFYLEEDVSLVSVRLLFDGVYMNTQIYINGQVLGYYPNGYTPFSYDITPYLRNDGTANQLAVFVENQQPSSRWYSGSGIYREVKLLITDSVHLDLYGSKIKSPKLKEQRDGWVETQLTSKVSNDGPQSVSVYLEQSIWYEGQQLSDWQATDSVVIESGEKHHFKQAISIFQPLLWDIDHPHLYQLKTRIYKNGILVDEGEESFGYRYMDWQADKGFFLNGRWLKIHGVCLHHDYGALGAVENRSAAERRLRQMKEMGVNAIRITHNPASGILLDVAAKMGLLIQEEAFDTWYGGKKEYDYGRFFEEEATHPEAKAGDFWSDYDLRTMIERGKNNPAIFMWSLGNEVSEANGDAHSLKTIKRLLERVKEVDDSRFVTIGMDQFRFGDGSGGHEKIADLLDVVGLNYSEDNIDAIRKRHPKWRLYGSETSSATRTRDSYFRPDKEWVGDNRRVRNFEQSDYGNDRVPWGKTATASWIADRNRLDYAGQFIWTGVDYIGEPTPWHNQNDTPVKSSYFGIVDTAGIPKNDYYLYQSQWVDLDQHPMVHILPHWNWEIHKSYQQVVDKYGDIPVRVYSNARSVELFLNGKSQGRKTFQEKWTSGGRKYQEGQSSDQLYLEWCLAYQPGELRAVAYDCQGQLVAEDRVVTAGKPAKIGLHAEKTKLEPDGQDLLYLYFDVLDKSGNWVPSASNQLHFKIEGPAHIVGVDNGRQASRERYKAQKNGRFQRKAFHGRGVLLVQSLEQAGLVSEYKLVLEG
>NC_013853.1|WP_004235732.1|2076420_2077305_-|SPFH-domain-containing-protein
MIFVVVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGIHIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKLMRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLITKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQRKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPNGVDDIRTQILSALRAEKK
>NC_013853.1|WP_000724053.1|2079039_2080545_-|zinc-ABC-transporter-substrate-binding-lipoprotein-AdcA
MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQVAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKKKVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLSADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQVAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLNPLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDADVKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTKINITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFSDHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLVH
>NC_013853.1|WP_000950038.1|2080554_2081361_-|metal-ABC-transporter-permease
MLSLLSYDFMQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLSHVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVSLIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFDEDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKSVMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFLLISLVRRFIK
>NC_013853.1|WP_001269498.1|2081353_2082058_-|metal-ABC-transporter-ATP-binding-protein
MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTTLIKASLGILQPRIGKVTISTTNTQGKKLRMAYLPQQIASFNAGFPSTVYEFVKSGRYPRKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVISRMFASDPDVFILDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSPWRCFNVHENDQEVGHA

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	113396-113444	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	149657-149705	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1147923-1147971	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1159094-1159142	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1416602-1416650	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1517921-1517969	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1891572-1891620	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1893130-1893178	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	2009311-2009359	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	39938-39986	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	390683-390731	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	611296-611344	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	697281-697329	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	736836-736884	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	738392-738440	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	739948-739996	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	741504-741552	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	813040-813088	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	882361-882409	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	943722-943770	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1297206-1297254	0	1.0
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1051563-1051611	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1070536-1070584	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1412178-1412226	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1425644-1425692	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1536827-1536875	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1855040-1855088	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1930231-1930279	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	1964116-1964164	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	2017951-2017999	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	14787-14835	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	29343-29391	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	201054-201102	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	233844-233892	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	237013-237061	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	248927-248975	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	296607-296655	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	459088-459136	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	560837-560885	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	562393-562441	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	635227-635275	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	914823-914871	1	0.98
NC_013853_1	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	NC_013853.1	945278-945326	1	0.98

1. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 113396-113444, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

2. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 149657-149705, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

3. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1147923-1147971, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

4. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1159094-1159142, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

5. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1416602-1416650, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

6. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1517921-1517969, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

7. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1891572-1891620, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

8. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1893130-1893178, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

9. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 2009311-2009359, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

10. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 39938-39986, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

11. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 390683-390731, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

12. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 611296-611344, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

13. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 697281-697329, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

14. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 736836-736884, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

15. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 738392-738440, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

16. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 739948-739996, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

17. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 741504-741552, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

18. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 813040-813088, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

19. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 882361-882409, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

20. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 943722-943770, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

21. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1297206-1297254, mismatch: 0, identity: 1.0

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	Protospacer
*************************************************

22. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1051563-1051611, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

23. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1070536-1070584, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

24. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1412178-1412226, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

25. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1425644-1425692, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

26. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1536827-1536875, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

27. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1855040-1855088, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

28. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1930231-1930279, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

29. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 1964116-1964164, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

30. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 2017951-2017999, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

31. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 14787-14835, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

32. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 29343-29391, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

33. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 201054-201102, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

34. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 233844-233892, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

35. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 237013-237061, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

36. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 248927-248975, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

37. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 296607-296655, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

38. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 459088-459136, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

39. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 560837-560885, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

40. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 562393-562441, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

41. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 635227-635275, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

42. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 914823-914871, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

43. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to position: 945278-945326, mismatch: 1, identity: 0.98

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448641	Streptococcus satellite phage Javan753, complete genome	2187-2217	0	1.0
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448628	Streptococcus satellite phage Javan741, complete genome	3052-3082	0	1.0
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448615	Streptococcus satellite phage Javan728, complete genome	3051-3081	0	1.0
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448420	Streptococcus satellite phage Javan309, complete genome	2778-2808	0	1.0
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448620	Streptococcus satellite phage Javan733, complete genome	3053-3083	0	1.0
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448614	Streptococcus satellite phage Javan727, complete genome	3128-3158	0	1.0
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448640	Streptococcus satellite phage Javan752, complete genome	1927-1957	0	1.0
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448619	Streptococcus satellite phage Javan732, complete genome	3128-3158	0	1.0
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448610	Streptococcus satellite phage Javan723, complete genome	2638-2668	0	1.0
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448623	Streptococcus satellite phage Javan736, complete genome	2108-2138	0	1.0
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448433	Streptococcus satellite phage Javan328, complete genome	2779-2809	1	0.968
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	MK448889	Streptococcus phage Javan262, complete genome	13152-13182	6	0.806
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NZ_CP054260	Lactobacillus plantarum strain TCI507 plasmid unnamed1	75-105	7	0.774
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NZ_CP020099	Lactobacillus plantarum strain K25 plasmid unnamed6, complete sequence	8125-8155	8	0.742
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NZ_CP015129	Lactobacillus plantarum strain CAUH2 plasmid pCAUH203, complete sequence	5127-5157	8	0.742
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NZ_CP032661	Lactobacillus pentosus strain ZFM94 plasmid unnamed2, complete sequence	8386-8416	8	0.742
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NZ_CP032661	Lactobacillus pentosus strain ZFM94 plasmid unnamed2, complete sequence	22239-22269	8	0.742
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NC_021520	Lactobacillus plantarum 16 plasmid Lp16L, complete sequence	1701-1731	8	0.742
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NZ_CP028234	Lactobacillus plantarum strain SRCM101222 plasmid unnamed5, complete sequence	12876-12906	8	0.742
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NZ_CP028246	Lactobacillus plantarum strain SRCM101518 plasmid unnamed5, complete sequence	8548-8578	8	0.742
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NZ_CP032657	Lactobacillus pentosus strain ZFM222 plasmid unnamed3, complete sequence	8799-8829	8	0.742
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NZ_CP013154	Lactobacillus plantarum strain MF1298 plasmid pMF1298-7, complete sequence	6717-6747	8	0.742
NC_013853_4	4.1\|2065634\|31\|NC_013853\|CRISPRCasFinder	2065634-2065664	31	NZ_CP054260	Lactobacillus plantarum strain TCI507 plasmid unnamed1	7422-7452	8	0.742

1. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448641 (Streptococcus satellite phage Javan753, complete genome) position: , mismatch: 0, identity: 1.0

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacgtttttagcctact	Protospacer
*******************************

2. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448628 (Streptococcus satellite phage Javan741, complete genome) position: , mismatch: 0, identity: 1.0

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacgtttttagcctact	Protospacer
*******************************

3. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448615 (Streptococcus satellite phage Javan728, complete genome) position: , mismatch: 0, identity: 1.0

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacgtttttagcctact	Protospacer
*******************************

4. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448420 (Streptococcus satellite phage Javan309, complete genome) position: , mismatch: 0, identity: 1.0

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacgtttttagcctact	Protospacer
*******************************

5. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448620 (Streptococcus satellite phage Javan733, complete genome) position: , mismatch: 0, identity: 1.0

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacgtttttagcctact	Protospacer
*******************************

6. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448614 (Streptococcus satellite phage Javan727, complete genome) position: , mismatch: 0, identity: 1.0

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacgtttttagcctact	Protospacer
*******************************

7. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448640 (Streptococcus satellite phage Javan752, complete genome) position: , mismatch: 0, identity: 1.0

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacgtttttagcctact	Protospacer
*******************************

8. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448619 (Streptococcus satellite phage Javan732, complete genome) position: , mismatch: 0, identity: 1.0

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacgtttttagcctact	Protospacer
*******************************

9. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448610 (Streptococcus satellite phage Javan723, complete genome) position: , mismatch: 0, identity: 1.0

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacgtttttagcctact	Protospacer
*******************************

10. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448623 (Streptococcus satellite phage Javan736, complete genome) position: , mismatch: 0, identity: 1.0

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacgtttttagcctact	Protospacer
*******************************

11. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448433 (Streptococcus satellite phage Javan328, complete genome) position: , mismatch: 1, identity: 0.968

atagttgatttaacaacgtttttagcctact	CRISPR spacer
ttagttgatttaacaacgtttttagcctact	Protospacer
 ******************************

12. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to MK448889 (Streptococcus phage Javan262, complete genome) position: , mismatch: 6, identity: 0.806

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atagttgatttaacaacattttttgctgctt	Protospacer
*****************.***** **.  .*

13. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NZ_CP054260 (Lactobacillus plantarum strain TCI507 plasmid unnamed1) position: , mismatch: 7, identity: 0.774

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttttaacact	Protospacer
** ****** *************    .***

14. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NZ_CP020099 (Lactobacillus plantarum strain K25 plasmid unnamed6, complete sequence) position: , mismatch: 8, identity: 0.742

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttaacacttc	Protospacer
** ****** **************.* . ..

15. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NZ_CP015129 (Lactobacillus plantarum strain CAUH2 plasmid pCAUH203, complete sequence) position: , mismatch: 8, identity: 0.742

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttaacacttc	Protospacer
** ****** **************.* . ..

16. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NZ_CP032661 (Lactobacillus pentosus strain ZFM94 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttaacacttc	Protospacer
** ****** **************.* . ..

17. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NZ_CP032661 (Lactobacillus pentosus strain ZFM94 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.742

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttaacacttc	Protospacer
** ****** **************.* . ..

18. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NC_021520 (Lactobacillus plantarum 16 plasmid Lp16L, complete sequence) position: , mismatch: 8, identity: 0.742

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttaacacttc	Protospacer
** ****** **************.* . ..

19. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NZ_CP028234 (Lactobacillus plantarum strain SRCM101222 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.742

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttaacacttc	Protospacer
** ****** **************.* . ..

20. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NZ_CP028246 (Lactobacillus plantarum strain SRCM101518 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.742

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttaacacttc	Protospacer
** ****** **************.* . ..

21. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NZ_CP032657 (Lactobacillus pentosus strain ZFM222 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttaacacttc	Protospacer
** ****** **************.* . ..

22. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NZ_CP013154 (Lactobacillus plantarum strain MF1298 plasmid pMF1298-7, complete sequence) position: , mismatch: 8, identity: 0.742

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttaacacttc	Protospacer
** ****** **************.* . ..

23. spacer 4.1|2065634|31|NC_013853|CRISPRCasFinder matches to NZ_CP054260 (Lactobacillus plantarum strain TCI507 plasmid unnamed1) position: , mismatch: 8, identity: 0.742

atagttgatttaacaacgtttttagcctact	CRISPR spacer
atcgttgatataacaacgtttttaacacttc	Protospacer
** ****** **************.* . ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4187 : 62360

uncultured_virus(27.27%)

tRNA,protease,transposase,bacteriocin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000163947.1\|4187_4757_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_000258129.1\|4757_8267_+	transcription-repair coupling factor	NA	NA	NA	NA
WP_001234978.1\|8324_8591_+	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_000041912.1\|8583_8952_+	septum formation initiator family protein	NA	NA	NA	NA
WP_001224761.1\|9071_10340_+	serine hydrolase	NA	NA	NA	NA
WP_001209053.1\|10336_11614_+\|tRNA	tRNA lysidine(34) synthetase TilS	A0A0N7G7K4	Chrysochromulina_ericina_virus	5.3e-12	23.4
WP_000892177.1\|11618_12161_+	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	6.1e-10	28.8
WP_000744562.1\|12176_14135_+\|protease	ATP-dependent zinc metalloprotease FtsH	H8ZJI5	Ostreococcus_tauri_virus	6.0e-108	44.0
WP_000471943.1\|14253_14733_+	transcriptional regulator	NA	NA	NA	NA
WP_000163009.1\|15027_16194_-\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_000941921.1\|22056_22293_+	hypothetical protein	NA	NA	NA	NA
WP_012972411.1\|22523_23810_+	adenylosuccinate synthase	L7Y4J5	Megavirus	3.5e-72	37.1
WP_000386764.1\|24010_24478_+	nucleoside deaminase	NA	NA	NA	NA
WP_000701987.1\|24664_25108_+	dUTP diphosphatase	Q332E8	Clostridium_botulinum_C_phage	3.3e-30	48.0
WP_000691251.1\|25109_25649_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_193334360.1\|25659_27024_+	DNA repair protein RadA	NA	NA	NA	NA
WP_000672724.1\|27095_27791_+	TIGR00266 family protein	NA	NA	NA	NA
WP_000119799.1\|27950_28448_+	carbonic anhydrase	NA	NA	NA	NA
WP_000828208.1\|28472_29288_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_000163002.1\|29583_30750_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	9.7e-13	22.9
WP_000010168.1\|30989_31958_+	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	4.2e-46	35.5
WP_000603344.1\|32076_33048_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_164925498.1\|33535_33952_+	flagellar assembly protein H domain protein	NA	NA	NA	NA
WP_000358451.1\|35967_37470_+	hypothetical protein	NA	NA	NA	NA
WP_164925499.1\|38180_38375_+\|transposase	transposase	NA	NA	NA	NA
WP_193334361.1\|38298_39075_+\|transposase	transposase	A0A218MNE7	uncultured_virus	2.4e-12	24.5
WP_000163002.1\|40178_41345_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	9.7e-13	22.9
WP_164925501.1\|43652_44699_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_000175244.1\|44716_45592_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_000358440.1\|45739_48373_+	DNA polymerase I	A0A218MKQ4	uncultured_virus	1.9e-56	31.4
WP_000076491.1\|48455_48893_+	CoA-binding protein	NA	NA	NA	NA
WP_000009146.1\|49110_50121_-	YeiH family putative sulfate export transporter	NA	NA	NA	NA
WP_000366367.1\|50689_51859_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000616155.1\|51855_52626_+	DNA repair protein RecO	NA	NA	NA	NA
WP_000717437.1\|52622_53615_+	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_000136448.1\|53620_53854_+	acyl carrier protein	NA	NA	NA	NA
WP_000748701.1\|54305_55487_+	N-acetylmuramoyl-L-alanine amidase family protein	NA	NA	NA	NA
WP_001267146.1\|55569_56445_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000748692.1\|56642_57812_+	N-acetylmuramoyl-L-alanine amidase family protein	NA	NA	NA	NA
WP_000425304.1\|57964_58111_+\|bacteriocin	smi_0057.1 family bacteriocin-like peptide	NA	NA	NA	NA
WP_012972418.1\|58144_59491_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_001221865.1\|59487_60219_+	response regulator transcription factor	NA	NA	NA	NA
WP_000658145.1\|60701_60830_+\|bacteriocin	smi_0059.1 family bacteriocin-like peptide	NA	NA	NA	NA
WP_001004585.1\|60841_60997_+	hypothetical protein	NA	NA	NA	NA
WP_000180818.1\|61030_61228_+\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_000357249.1\|61441_61597_+\|bacteriocin	smi_0061 family bacteriocin-like peptide	NA	NA	NA	NA
WP_000673799.1\|62153_62360_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA

DBSCAN-SWA_2

112036 : 182479

Bacillus_phage(23.53%)

tRNA,protease,transposase,integrase

attL 116392:116406|attR 184292:184306

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000163005.1\|112036_113203_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.8e-11	22.9
WP_000796544.1\|113511_113712_-	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
WP_000171574.1\|113714_113855_-	hypothetical protein	NA	NA	NA	NA
WP_000460909.1\|114045_116076_+	BglG family transcription antiterminator	NA	NA	NA	NA
WP_000912475.1\|116079_116364_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
WP_000975304.1\|116376_117723_+	PTS ascorbate transporter subunit IIC	NA	NA	NA	NA
116392:116406	attL	NA	NA	NA	NA
WP_000603568.1\|117726_118584_+	transketolase	A0A2K9L6P9	Tupanvirus	1.7e-30	32.4
WP_000986410.1\|118580_119513_+	transketolase family protein	NA	NA	NA	NA
WP_000137348.1\|119743_121447_+	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_001206379.1\|121658_122000_-	metal-sulfur cluster assembly factor	NA	NA	NA	NA
WP_000434945.1\|122123_122975_+	transcriptional regulator Rgg	NA	NA	NA	NA
WP_000770648.1\|123280_124528_+	hypothetical protein	NA	NA	NA	NA
WP_000775865.1\|124605_125895_+\|tRNA	histidine--tRNA ligase	NA	NA	NA	NA
WP_000565864.1\|125991_126456_+	hypothetical protein	NA	NA	NA	NA
WP_001176232.1\|126465_126672_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001046132.1\|126671_126869_+	hypothetical protein	NA	NA	NA	NA
WP_000730204.1\|126871_127609_+	DUF3169 family protein	NA	NA	NA	NA
WP_000621679.1\|127619_128444_+	ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	1.3e-19	31.4
WP_000488859.1\|128436_129135_+	ABC transporter permease	NA	NA	NA	NA
WP_000771020.1\|129144_129786_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000832196.1\|129803_130034_+	membrane protein	NA	NA	NA	NA
WP_000830900.1\|130168_131932_+\|tRNA	aspartate--tRNA ligase	A0A1V0SJ84	Klosneuvirus	3.9e-13	26.4
WP_000806274.1\|131909_132851_+	YitT family protein	NA	NA	NA	NA
WP_001145423.1\|132880_133867_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_000938246.1\|133876_134677_-	DUF1189 domain-containing protein	NA	NA	NA	NA
WP_001065643.1\|134937_135780_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_000414956.1\|135781_137074_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_000095472.1\|137184_138456_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_000747274.1\|138935_140453_+	4-alpha-glucanotransferase	NA	NA	NA	NA
WP_000950133.1\|140478_142737_+	glycogen/starch/alpha-glucan family phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	1.9e-09	38.6
WP_001095525.1\|143414_144263_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_000910903.1\|144414_144693_+	hypothetical protein	NA	NA	NA	NA
WP_000008810.1\|144694_146755_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.0e-53	26.5
WP_000546885.1\|146831_148088_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	5.1e-76	39.8
WP_000163003.1\|148297_149464_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9
WP_012972427.1\|152304_153216_+	DMT family transporter	NA	NA	NA	NA
WP_000127457.1\|153444_154143_+	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase	NA	NA	NA	NA
WP_000886120.1\|154210_155341_+	N-acetyldiaminopimelate deacetylase	NA	NA	NA	NA
WP_000834298.1\|155352_155892_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_000658489.1\|155875_156553_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_000202213.1\|156617_157517_-	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	4.8e-76	50.3
WP_000415117.1\|157538_158555_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000084861.1\|158722_158968_-	hypothetical protein	NA	NA	NA	NA
WP_001092709.1\|159468_161160_-\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	7.8e-80	32.2
WP_001231476.1\|161295_161742_+	arginine repressor	NA	NA	NA	NA
WP_000179937.1\|161792_164327_+	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	4.2e-37	23.2
WP_000908161.1\|164472_166179_+	multidrug efflux ABC transporter subunit PatA	W8CYL7	Bacillus_phage	2.8e-45	29.0
WP_000859877.1\|166180_167947_+	multidrug efflux ABC transporter subunit PatB	W8CYL7	Bacillus_phage	9.1e-39	26.4
WP_001138350.1\|168237_168927_+	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_000057438.1\|169103_169568_+\|transposase	IS200/IS605 family transposase	A0A1P8BMC0	Lactococcus_phage	3.4e-17	36.8
WP_000018273.1\|169852_171202_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_000031057.1\|171331_172792_+\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_000355920.1\|172805_173240_+	cytidine deaminase	NA	NA	NA	NA
WP_001074366.1\|179691_180423_-	serine/threonine protein phosphatase	A0A127AVW0	Bacillus_phage	1.7e-10	29.2
WP_001067142.1\|180415_180652_-	ribbon-helix-helix protein, CopG family	NA	NA	NA	NA
WP_000381519.1\|180867_181305_-	HD domain-containing protein	A0A060QNR4	Streptococcus_phage	2.1e-37	63.3
WP_001007697.1\|181345_182479_-\|integrase	site-specific integrase	A0A1B2AQ00	Phage_Wrath	3.8e-38	36.1
184292:184306	attR	NA	NA	NA	NA

DBSCAN-SWA_3

234084 : 298014

Staphylococcus_prophage(33.33%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000163009.1\|234084_235251_-\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_012972434.1\|235430_235583_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_001210991.1\|235592_235769_+	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_000376727.1\|235823_236360_+	transcription termination/antitermination protein NusG	NA	NA	NA	NA
WP_000471943.1\|236479_236959_+	transcriptional regulator	NA	NA	NA	NA
WP_000163009.1\|237253_238420_-\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_025170907.1\|244914_245121_+	hypothetical protein	NA	NA	NA	NA
WP_000708869.1\|245117_245312_+	hypothetical protein	NA	NA	NA	NA
WP_001055974.1\|245298_246183_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	3.6e-20	32.5
WP_012972436.1\|246184_246922_+	ABC transporter permease	NA	NA	NA	NA
WP_000893535.1\|246921_248019_+	sensor histidine kinase	NA	NA	NA	NA
WP_000772075.1\|248020_248620_+	response regulator transcription factor	NA	NA	NA	NA
WP_000163009.1\|249167_250334_-\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_001142335.1\|250642_251056_+	30S ribosomal protein S12	NA	NA	NA	NA
WP_000087873.1\|251075_251546_+	30S ribosomal protein S7	NA	NA	NA	NA
WP_000090357.1\|251940_254022_+	elongation factor G	E4ZFJ7	Streptococcus_phage	9.7e-64	29.0
WP_000071439.1\|254125_258517_+	PolC-type DNA polymerase III	A0A0K2SUJ2	Clostridium_phage	2.8e-20	38.5
WP_000047862.1\|258618_258882_+	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_000916506.1\|258874_259153_+	type II toxin-antitoxin system YafQ family toxin	NA	NA	NA	NA
WP_000243934.1\|259346_260588_+	aminopeptidase	NA	NA	NA	NA
WP_000901572.1\|260597_260828_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_001234916.1\|261051_261774_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000991650.1\|261884_263216_+	aminopeptidase C	NA	NA	NA	NA
WP_001059647.1\|263357_264674_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	4.1e-44	33.3
WP_000493216.1\|264935_265514_+	DUF4230 domain-containing protein	NA	NA	NA	NA
WP_004238875.1\|265680_265926_+	hypothetical protein	NA	NA	NA	NA
WP_164925540.1\|266597_266993_+	leucine-rich repeat protein	NA	NA	NA	NA
WP_000136858.1\|267227_268139_-	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_001280328.1\|268153_268966_-	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_000021971.1\|269040_270030_-	PTS mannose transporter subunit IIAB	NA	NA	NA	NA
WP_000649180.1\|270274_271294_-	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	2.1e-27	25.9
WP_000162342.1\|271716_272529_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_000359256.1\|272718_274137_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	7.6e-44	31.2
WP_000391627.1\|274189_274897_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000240961.1\|275097_276078_+	dihydropteroate synthase	NA	NA	NA	NA
WP_000657452.1\|276079_277402_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_000380923.1\|277382_277937_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	6.4e-39	43.8
WP_000372490.1\|278094_278907_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_000886035.1\|278951_279269_-	DUF960 domain-containing protein	NA	NA	NA	NA
WP_001090627.1\|279505_280516_+	catabolite control protein A	NA	NA	NA	NA
WP_001124787.1\|280569_281532_-	asparaginase	NA	NA	NA	NA
WP_000452107.1\|281597_282989_+	Cof-type HAD-IIB family hydrolase	A0A0H3UZF4	Geobacillus_virus	4.8e-19	38.5
WP_000079151.1\|283166_283619_-	universal stress protein	NA	NA	NA	NA
WP_164925505.1\|283779_284082_+	hypothetical protein	NA	NA	NA	NA
WP_000666463.1\|284237_285452_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000831905.1\|285596_285731_+	50S ribosomal protein L34	NA	NA	NA	NA
WP_000748903.1\|285869_287834_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000494369.1\|287925_289770_-	APC family permease	NA	NA	NA	NA
WP_000575604.1\|289924_290695_+	TatD family hydrolase	NA	NA	NA	NA
WP_000660021.1\|290697_291264_+	ribonuclease M5	NA	NA	NA	NA
WP_001216839.1\|291328_292201_+	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_012972439.1\|292202_293081_+	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_000084984.1\|293091_293748_+	ribulose-phosphate 3-epimerase	NA	NA	NA	NA
WP_000006115.1\|293710_294373_+	thiamine diphosphokinase	NA	NA	NA	NA
WP_000444605.1\|294374_295631_+	DNA recombination protein RmuC	NA	NA	NA	NA
WP_000703195.1\|295620_296562_+	3'-5' exoribonuclease YhaM family protein	NA	NA	NA	NA
WP_000163008.1\|296847_298014_-\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	3.7e-12	22.6

DBSCAN-SWA_4

390923 : 479357

105

Streptococcus_phage(53.03%)

plate,terminase,portal,capsid,transposase,tail,holin,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000163003.1\|390923_392090_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9
WP_012972450.1\|392301_392904_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_000105231.1\|393139_394747_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	8.1e-143	47.5
WP_001013971.1\|396030_396330_+	DUF4651 domain-containing protein	NA	NA	NA	NA
WP_000615777.1\|396326_396644_+	thioredoxin family protein	NA	NA	NA	NA
WP_000578290.1\|396659_397286_+\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_001107784.1\|397328_398090_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_001244955.1\|398224_399646_-	recombinase family protein	K4JU73	Streptococcus_phage	1.1e-119	48.8
WP_000525227.1\|399762_400020_-	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_000580488.1\|400043_400784_-	helix-turn-helix transcriptional regulator	A0A1S5S8S8	Streptococcus_phage	2.7e-109	79.6
WP_164925542.1\|400958_401159_+	helix-turn-helix transcriptional regulator	A0A1S5S8R4	Streptococcus_phage	7.1e-25	86.4
WP_164925507.1\|401394_401631_-	hypothetical protein	A0A1S5SDG8	Streptococcus_phage	2.8e-36	93.6
WP_000656669.1\|401690_402050_+	hypothetical protein	X2KUC5	Streptococcus_phage	4.4e-17	84.9
WP_000492049.1\|402106_402583_-	hypothetical protein	NA	NA	NA	NA
WP_001247369.1\|402631_402793_+	hypothetical protein	A0A1S5SBJ3	Streptococcus_phage	1.6e-19	96.2
WP_001050935.1\|403007_403190_+	hypothetical protein	NA	NA	NA	NA
WP_000462833.1\|403182_403509_+	hypothetical protein	Q708Q6	Streptococcus_phage	9.2e-30	58.3
WP_000189403.1\|403815_404157_+	hypothetical protein	A0A1S5SA87	Streptococcus_phage	1.5e-51	88.5
WP_000157809.1\|404156_404630_+	siphovirus Gp157 family protein	A0A2H4JBT9	uncultured_Caudovirales_phage	2.3e-74	90.4
WP_000704952.1\|404626_405328_+	AAA family ATPase	A0A2H4JI15	uncultured_Caudovirales_phage	2.4e-131	97.9
WP_012972453.1\|405284_406694_+	DEAD/DEAH box helicase	A0A2H4JBQ0	uncultured_Caudovirales_phage	6.9e-247	90.0
WP_001173389.1\|406699_407182_+	DUF669 domain-containing protein	A0A2H4JER1	uncultured_Caudovirales_phage	2.7e-78	94.4
WP_000232980.1\|407185_407983_+	bifunctional DNA primase/polymerase	A0A2H4JBR5	uncultured_Caudovirales_phage	6.2e-136	90.2
WP_012972454.1\|407918_409523_+	DNA primase family protein	A0A2H4JBQ3	uncultured_Caudovirales_phage	8.3e-289	90.2
WP_000834374.1\|409775_410084_+	VRR-NUC domain-containing protein	A0A2H4JH82	uncultured_Caudovirales_phage	4.2e-48	93.1
WP_000580653.1\|410165_410330_+	hypothetical protein	A0A141E182	Streptococcus_phage	2.8e-19	83.3
WP_001105093.1\|410319_410505_+	hypothetical protein	A0A1S5SCV3	Streptococcus_phage	9.6e-08	54.5
WP_001064589.1\|410501_411014_+	DUF1642 domain-containing protein	A0A141E0F2	Streptococcus_phage	2.8e-33	45.9
WP_000183521.1\|411016_411358_+	hypothetical protein	H9EFD9	Lactococcus_phage	3.8e-18	42.0
WP_000429371.1\|411358_411694_+	hypothetical protein	C5J997	Streptococcus_phage	5.8e-27	72.6
WP_000367272.1\|411706_411982_+	hypothetical protein	Q708P5	Streptococcus_phage	2.6e-41	98.9
WP_000819324.1\|411978_412239_+	DUF1372 family protein	Q708P4	Streptococcus_phage	1.0e-39	95.2
WP_000670048.1\|412235_413378_+	DNA cytosine methyltransferase	A0A1S5SEK0	Streptococcus_phage	1.5e-183	88.9
WP_001092015.1\|413374_413863_+	DNA-binding protein	A0A1S5SA39	Streptococcus_phage	2.0e-65	77.2
WP_000733001.1\|413864_414143_+	hypothetical protein	A0A1S5SG07	Streptococcus_phage	9.9e-41	96.7
WP_000131521.1\|414155_414380_+	DUF3310 domain-containing protein	A0A1S5S8G0	Streptococcus_phage	4.5e-20	62.5
WP_000125656.1\|414400_414754_-	type II toxin-antitoxin system PemK/MazF family toxin	A0A1S5SEX8	Streptococcus_phage	4.9e-61	99.1
WP_001098944.1\|414737_414953_-	AbrB family transcriptional regulator	A0A1S5SET9	Streptococcus_phage	1.3e-32	98.6
WP_001237895.1\|415083_415530_+	transcriptional regulator	Q708N7	Streptococcus_phage	5.8e-75	96.6
WP_164925544.1\|415939_416386_+\|terminase	terminase small subunit	I1W650	Staphylococcus_phage	1.1e-33	61.1
WP_000830192.1\|416375_417632_+\|terminase	PBSX family phage terminase large subunit	D2J001	Enterococcus_phage	4.5e-181	73.2
WP_164925508.1\|417646_419071_+\|portal	phage portal protein	S6BFK8	Thermus_phage	1.4e-114	48.1
WP_000206122.1\|419039_420800_+\|capsid	minor capsid protein	S6B1L4	Thermus_phage	1.1e-65	46.2
WP_000853282.1\|420796_421129_+	hypothetical protein	NA	NA	NA	NA
WP_000877351.1\|421171_421450_+	hypothetical protein	A6MAI4	Lactococcus_virus	9.9e-33	69.2
WP_000747923.1\|421824_422031_-	hypothetical protein	NA	NA	NA	NA
WP_001080210.1\|422170_422737_+	phage scaffolding protein	S6B9Y2	Thermus_phage	2.6e-19	36.4
WP_001111858.1\|422762_423677_+	hypothetical protein	Q20DD4	Lactobacillus_phage	3.6e-79	51.3
WP_000958638.1\|423691_423952_+	hypothetical protein	NA	NA	NA	NA
WP_000415586.1\|423969_424323_+	hypothetical protein	NA	NA	NA	NA
WP_001024431.1\|424324_424681_+	hypothetical protein	NA	NA	NA	NA
WP_000017386.1\|424667_425096_+	HK97 gp10 family phage protein	A9D9U1	Lactobacillus_prophage	6.5e-15	39.0
WP_000386589.1\|425085_425508_+	hypothetical protein	NA	NA	NA	NA
WP_000425197.1\|425494_425695_+	hypothetical protein	NA	NA	NA	NA
WP_000090007.1\|425694_426978_+\|tail	phage tail sheath subtilisin-like domain-containing protein	S6B1K7	Thermus_phage	2.4e-89	41.7
WP_000996593.1\|426996_427461_+\|tail	phage tail tube protein	S6C462	Thermus_phage	1.1e-36	48.0
WP_061439172.1\|427479_427881_+\|portal	phage portal protein	S6B9X5	Thermus_phage	1.9e-37	57.9
WP_164925509.1\|428049_430497_+	tape measure protein	S6AVU8	Thermus_phage	1.6e-49	25.7
WP_000469518.1\|430511_431174_+	LysM peptidoglycan-binding domain-containing protein	A0A0A7RW06	Clostridium_phage	9.0e-32	39.0
WP_000983379.1\|431170_432136_+	hypothetical protein	Q708L5	Streptococcus_phage	1.4e-46	33.8
WP_000451988.1\|432136_432433_+	DUF2577 family protein	NA	NA	NA	NA
WP_000106741.1\|432429_432828_+	DUF2634 domain-containing protein	S6B9X2	Thermus_phage	2.4e-08	37.9
WP_000598577.1\|432824_433880_+\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	5.4e-47	33.4
WP_000084596.1\|433866_434385_+	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_012972458.1\|434395_435544_+\|tail	tail fiber protein	Q708K9	Streptococcus_phage	3.5e-15	61.4
WP_000268494.1\|435545_435944_+	hypothetical protein	Q708K8	Streptococcus_phage	8.7e-22	47.5
WP_000235460.1\|435952_436384_+	hypothetical protein	Q708K7	Streptococcus_phage	7.7e-08	32.3
WP_000397492.1\|436387_437119_+	hypothetical protein	Q708K6	Streptococcus_phage	1.2e-74	79.5
WP_000807223.1\|437130_437409_+	hypothetical protein	A0A1S5SAG1	Streptococcus_phage	6.6e-37	91.2
WP_000501868.1\|437423_437909_+	hypothetical protein	Q708K4	Streptococcus_phage	5.0e-56	69.6
WP_000381257.1\|437912_438233_+	hypothetical protein	Q708K3	Streptococcus_phage	2.2e-44	91.5
WP_012972459.1\|438229_438865_+	hypothetical protein	NA	NA	NA	NA
WP_000191484.1\|438878_439214_+\|holin	phage holin	A0A2H4JDE8	uncultured_Caudovirales_phage	3.2e-46	87.3
WP_000350519.1\|439213_440170_+	N-acetylmuramoyl-L-alanine amidase family protein	A0A060QRT9	Streptococcus_phage	2.4e-142	88.7
WP_000276229.1\|440328_442014_-\|transposase	IS1182-like element ISSmi2 family transposase	A0A146ICT8	Staphylococcus_phage	3.7e-106	41.1
WP_000580360.1\|442435_442813_+	single-stranded DNA-binding protein	A1EAD1	Streptococcus_phage	2.3e-24	44.4
WP_000917323.1\|442968_443253_+	co-chaperone GroES	NA	NA	NA	NA
WP_000031562.1\|443268_444891_+	chaperonin GroEL	A0A219YK78	uncultured_virus	1.3e-153	55.8
WP_000567572.1\|445028_445796_+	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_000566050.1\|446195_446969_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000800707.1\|446981_447839_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_000775316.1\|448196_448730_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_000705110.1\|448818_449595_-	recombination regulator RecX	NA	NA	NA	NA
WP_001050279.1\|449632_451000_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	E4ZFI6	Streptococcus_phage	7.0e-71	33.7
WP_000844501.1\|457946_458882_-	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor	NA	NA	NA	NA
WP_000163009.1\|459328_460495_-\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_000835615.1\|460721_461915_+	O-antigen ligase family protein	NA	NA	NA	NA
WP_000872570.1\|462059_462503_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000575206.1\|462743_463472_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.0e-29	36.7
WP_000182950.1\|463464_464985_+	ABC transporter permease/substrate-binding protein	NA	NA	NA	NA
WP_000181706.1\|465122_465659_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000645151.1\|465791_466682_+	cation transporter	NA	NA	NA	NA
WP_000212502.1\|466824_467829_-	DNA-binding transcriptional regulator GalR	NA	NA	NA	NA
WP_000191948.1\|467992_469171_+	galactokinase	NA	NA	NA	NA
WP_000176978.1\|469189_470671_+	UDP-glucose--hexose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_000651198.1\|470740_471145_+	PaaI family thioesterase	NA	NA	NA	NA
WP_012972462.1\|471301_472156_+	DNA adenine methylase	A0A1S5PRR3	Streptococcus_phage	5.3e-93	61.9
WP_025169873.1\|472181_472937_+	site-specific DNA-methyltransferase	M1Q227	Streptococcus_phage	4.5e-27	32.8
WP_000891182.1\|472941_473751_+	hypothetical protein	NA	NA	NA	NA
WP_001050800.1\|473763_474672_+	type II restriction endonuclease	NA	NA	NA	NA
WP_001194464.1\|474717_475980_-	purine permease	Q9KX94	Enterobacteria_phage	5.0e-31	29.0
WP_000770415.1\|475979_476561_-	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_000386220.1\|477012_477399_-	VOC family protein	NA	NA	NA	NA
WP_000767454.1\|477410_478238_-	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	2.4e-127	80.6
WP_000066795.1\|478457_479357_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_5

511430 : 517927

Pneumococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000082587.1\|511430_511922_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	7.6e-44	60.2
WP_000196451.1\|511940_512657_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	2.2e-63	47.7
WP_000464576.1\|512649_513093_-	6-carboxytetrahydropterin synthase QueD	J9PV91	Bacillus_phage	6.9e-44	62.2
WP_000828762.1\|513092_513746_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	5.9e-60	54.2
WP_001029579.1\|513947_514262_-	thioredoxin	A0A1J0GW78	Streptomyces_phage	6.6e-17	47.2
WP_000570254.1\|514277_514499_-	DUF4649 family protein	NA	NA	NA	NA
WP_000221636.1\|514596_514977_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000781329.1\|515261_515636_+	CidA/LrgA family protein	NA	NA	NA	NA
WP_001288948.1\|515632_516328_+	LrgB family protein	NA	NA	NA	NA
WP_000946120.1\|516379_517927_-	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	6.2e-15	27.3

DBSCAN-SWA_6

691116 : 742911

Staphylococcus_prophage(31.25%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000152243.1\|691116_691869_+\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_000111588.1\|691981_692887_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_000742924.1\|693045_694203_+	ABC transporter ATP-binding protein	Q6GZ03	Mycoplasma_phage	5.8e-34	40.4
WP_000753801.1\|694183_694990_+	ABC transporter permease	Q6GZ02	Mycoplasma_phage	2.5e-12	26.5
WP_000712742.1\|694986_695760_+	ABC transporter permease	NA	NA	NA	NA
WP_000737955.1\|695756_696827_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000163010.1\|697521_698688_-\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	4.8e-12	22.9
WP_000847065.1\|699059_699545_+	LURP-one-related family protein	NA	NA	NA	NA
WP_000811741.1\|699566_702185_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	3.7e-60	33.8
WP_001181049.1\|702426_703881_-	alpha-amylase	NA	NA	NA	NA
WP_000569179.1\|704058_704808_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-28	28.1
WP_001237547.1\|704788_706423_+	hypothetical protein	NA	NA	NA	NA
WP_164925551.1\|706999_709117_-	sulfatase-like hydrolase/transferase	W6LM83	Streptococcus_phage	4.2e-224	58.1
WP_164925515.1\|709266_710430_+	class I SAM-dependent methyltransferase	W6LLI2	Streptococcus_phage	1.9e-141	64.3
WP_000767783.1\|710426_711104_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	1.4e-83	66.8
WP_000762502.1\|711093_711948_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_000702179.1\|711966_713034_+	3-dehydroquinate synthase	NA	NA	NA	NA
WP_001269854.1\|713043_714210_+	chorismate synthase	A0A291AU41	Pandoravirus	3.5e-39	34.9
WP_001140860.1\|714219_715323_+	prephenate dehydrogenase	NA	NA	NA	NA
WP_000065979.1\|715333_715672_+	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	2.4e-25	50.9
WP_000734773.1\|716648_717791_+	TPM domain-containing protein	NA	NA	NA	NA
WP_000769891.1\|717912_719196_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_001151370.1\|719188_719665_+	shikimate kinase	NA	NA	NA	NA
WP_000686443.1\|719661_720510_+	prephenate dehydratase	NA	NA	NA	NA
WP_000032335.1\|720506_721817_+	LCP family protein	NA	NA	NA	NA
WP_165442199.1\|721951_722788_+	LicD family protein	NA	NA	NA	NA
WP_000225909.1\|722777_723881_+	glycosyltransferase	NA	NA	NA	NA
WP_000446968.1\|723882_724869_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_000565077.1\|724884_726354_+	O-antigen polysaccharide polymerase Wzy family protein	NA	NA	NA	NA
WP_000461488.1\|726346_727381_+	hypothetical protein	NA	NA	NA	NA
WP_000782679.1\|727686_728424_+	adaptor protein MecA	NA	NA	NA	NA
WP_000216350.1\|728574_729861_+	homoserine dehydrogenase	NA	NA	NA	NA
WP_000692421.1\|729862_730732_+	homoserine kinase	NA	NA	NA	NA
WP_000818187.1\|730945_731884_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_000681739.1\|731944_733669_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	9.8e-46	28.6
WP_001254278.1\|733670_735419_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.6e-46	28.7
WP_000163003.1\|737076_738243_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9
WP_000163003.1\|738632_739799_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9
WP_000163003.1\|740188_741355_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9
WP_000163003.1\|741744_742911_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9

DBSCAN-SWA_7

881526 : 946685

Streptococcus_phage(37.5%)

tRNA,protease,transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000613699.1\|881526_881871_+\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_000916509.1\|881887_882181_+	50S ribosomal protein L27	NA	NA	NA	NA
WP_000163002.1\|882601_883768_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	9.7e-13	22.9
WP_001025693.1\|883967_884876_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	4.0e-06	27.0
WP_000745687.1\|884872_885334_+	signal peptidase II	NA	NA	NA	NA
WP_000403233.1\|885323_886211_+	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_000727870.1\|887395_889279_+\|holin	phosphorylcholine esterase CbpE	Q332B9	Clostridium_botulinum_C_phage	2.5e-10	23.7
WP_012972504.1\|889358_890489_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	5.9e-116	59.2
WP_000255283.1\|890498_891761_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	4.2e-139	64.5
WP_000689692.1\|891764_892562_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	7.2e-60	50.9
WP_000033358.1\|892791_893430_+	dTMP kinase	M1PSC7	Streptococcus_phage	7.5e-76	68.1
WP_000806711.1\|893426_894317_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	9.8e-74	52.0
WP_000358228.1\|894356_894674_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-28	60.0
WP_001166903.1\|894676_895546_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	8.3e-118	76.8
WP_000760485.1\|895767_896823_+	DNA cytosine methyltransferase	M1PSQ0	Streptococcus_phage	1.9e-63	39.1
WP_000285316.1\|896825_898226_+	DUF3883 domain-containing protein	NA	NA	NA	NA
WP_000734158.1\|898222_899263_+	DNA (cytosine-5-)-methyltransferase	A7XXH6	Thermus_virus	1.6e-46	33.6
WP_000422392.1\|899287_900082_+	abortive infection family protein	NA	NA	NA	NA
WP_164925555.1\|900068_900659_+	SLATT domain-containing protein	NA	NA	NA	NA
WP_000059139.1\|900658_901981_+	nucleotidyltransferase	NA	NA	NA	NA
WP_000083741.1\|902173_903508_+\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_000002996.1\|903591_904329_+	UMP kinase	NA	NA	NA	NA
WP_001262225.1\|904337_904895_+	ribosome recycling factor	NA	NA	NA	NA
WP_001095453.1\|904954_905809_+	RNA-binding virulence regulatory protein CvfB	NA	NA	NA	NA
WP_001232084.1\|905817_906033_+	YozE family protein	NA	NA	NA	NA
WP_000658206.1\|906117_907122_+	PhoH family protein	W8D063	Erwinia_phage	3.6e-48	48.6
WP_000443760.1\|907208_907778_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000387350.1\|907844_908474_+	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_000942437.1\|908457_910698_+	DNA internalization-related competence protein ComEC/Rec2	M1PSD2	Streptococcus_phage	9.1e-52	57.6
WP_000939892.1\|911096_911684_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.0e-15	28.1
WP_000655831.1\|911687_912872_+	hypothetical protein	NA	NA	NA	NA
WP_000848180.1\|913179_913710_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	2.4e-11	32.1
WP_001125943.1\|913742_913943_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_000124834.1\|913994_914354_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_000157153.1\|914412_914793_+	VOC family protein	NA	NA	NA	NA
WP_000163009.1\|915063_916230_-\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_001070078.1\|916598_917399_+	dihydroorotate dehydrogenase electron transfer subunit	NA	NA	NA	NA
WP_164925518.1\|917361_918348_+	dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_000736100.1\|918445_920158_+	glucosaminidase domain-containing protein	A0A143FPM9	Bacillus_phage	3.9e-26	43.8
WP_000006748.1\|920319_921975_-	Rqc2 family fibronectin-binding protein PavA	A0A0P0YM59	Yellowstone_lake_phycodnavirus	3.3e-06	31.6
WP_000275156.1\|922079_922577_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_000378171.1\|922557_922953_+	diacylglycerol kinase	NA	NA	NA	NA
WP_000143256.1\|922969_923869_+	GTPase Era	NA	NA	NA	NA
WP_001114617.1\|923917_924742_+	DNA-formamidopyrimidine glycosylase	G3MA33	Bacillus_virus	9.5e-31	34.5
WP_000516169.1\|924741_925347_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_000136131.1\|925333_926533_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_001809104.1\|926532_926682_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_000282517.1\|926721_926955_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_000654875.1\|927055_929407_+	ribonuclease R	Q0GXV6	Lactococcus_phage	3.6e-91	40.8
WP_001051750.1\|929369_929837_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	4.2e-44	60.1
WP_000413776.1\|929851_930712_+	SAM-dependent methyltransferase TehB	NA	NA	NA	NA
WP_000468780.1\|931115_934772_+	YSIRK signal domain/LPXTG anchor domain surface protein	NA	NA	NA	NA
WP_000495918.1\|935047_936001_+	competence protein CoiA	NA	NA	NA	NA
WP_000244106.1\|936019_937822_+	oligoendopeptidase F	NA	NA	NA	NA
WP_012972506.1\|937823_938537_+	O-methyltransferase	NA	NA	NA	NA
WP_000727942.1\|938603_939542_+	peptidylprolyl isomerase PrsA	NA	NA	NA	NA
WP_000703373.1\|939702_940926_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_000058155.1\|940950_943647_+	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_000163000.1\|943962_945129_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9
WP_000163009.1\|945518_946685_-\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6

DBSCAN-SWA_8

1322661 : 1416409

Streptococcus_phage(56.41%)

tRNA,transposase,integrase,holin

attL 1317679:1317696|attR 1423106:1423123

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1317679:1317696	attL	NA	NA	NA	NA
WP_000181735.1\|1322661_1324455_+	ATP-dependent helicase	E3T5J8	Cafeteria_roenbergensis_virus	6.9e-26	23.8
WP_000421279.1\|1324654_1324969_+	YdcP family protein	A0A1S5SF38	Streptococcus_phage	1.2e-42	77.7
WP_001234191.1\|1324989_1325367_+	YdcP family protein	A0A1S5SF96	Streptococcus_phage	9.6e-47	76.4
WP_000185761.1\|1325376_1326150_+	hypothetical protein	NA	NA	NA	NA
WP_001130244.1\|1326171_1327575_+	DUF87 domain-containing protein	A0A1S5SFB5	Streptococcus_phage	2.2e-176	66.5
WP_000426689.1\|1327756_1328941_+	replication initiation factor domain-containing protein	A0A1S5SEX3	Streptococcus_phage	6.3e-161	68.1
WP_000055376.1\|1328937_1329228_+	hypothetical protein	NA	NA	NA	NA
WP_001009054.1\|1329224_1329446_+	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	3.1e-29	93.2
WP_000675717.1\|1329487_1330267_+	abortive infection family protein	NA	NA	NA	NA
WP_000870467.1\|1330333_1330828_+	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	2.8e-54	63.4
WP_000248477.1\|1330883_1331522_+	hypothetical protein	NA	NA	NA	NA
WP_000723887.1\|1331593_1331989_+	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	5.9e-47	72.6
WP_000331165.1\|1331972_1334426_+	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	78.9
WP_000192395.1\|1334422_1336450_+	membrane protein	A0A1S5SF30	Streptococcus_phage	2.3e-195	65.4
WP_000768374.1\|1336446_1337469_+	lysozyme family protein	A0A1S5SEZ8	Streptococcus_phage	1.4e-132	75.5
WP_000584387.1\|1337485_1338415_+	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	1.1e-83	56.6
WP_001814923.1\|1338659_1338776_+	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_000691748.1\|1338791_1340711_+	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	97.0
WP_032506803.1\|1340808_1340997_+	cysteine-rich KTR domain-containing protein	D0R0F6	Streptococcus_phage	7.4e-16	61.4
WP_001227350.1\|1341054_1341408_-	helix-turn-helix domain-containing protein	A0A1S5SFA6	Streptococcus_phage	2.2e-53	89.7
WP_000804880.1\|1341938_1342361_+	hypothetical protein	A0A1S5SEW0	Streptococcus_phage	2.8e-47	67.9
WP_000845143.1\|1342357_1342588_+	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	1.0e-27	78.9
WP_000633906.1\|1343085_1343286_+	DUF3173 family protein	NA	NA	NA	NA
WP_000237797.1\|1343312_1344506_+\|integrase	site-specific integrase	A0A0S2MV79	Bacillus_phage	8.3e-44	34.2
WP_012972538.1\|1344573_1346136_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.1e-19	32.8
WP_000936183.1\|1346277_1346976_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000071683.1\|1347017_1347914_-	EamA family transporter	NA	NA	NA	NA
WP_000872230.1\|1347922_1348858_-	serine hydrolase	NA	NA	NA	NA
WP_001102228.1\|1348854_1349580_-	proteinase	NA	NA	NA	NA
WP_000348097.1\|1349703_1350609_-	aquaporin family protein	NA	NA	NA	NA
WP_000771154.1\|1350733_1351753_-\|holin	choline-binding protein CbpC	NA	NA	NA	NA
WP_001024038.1\|1352100_1352964_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_001108625.1\|1353242_1354409_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_001019252.1\|1354421_1355162_-	esterase family protein	NA	NA	NA	NA
WP_001076720.1\|1355183_1356008_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001200061.1\|1356144_1357359_-\|tRNA	tRNA 4-thiouridine(8) synthase ThiI	NA	NA	NA	NA
WP_000638923.1\|1357367_1358510_-	cysteine desulfurase	NA	NA	NA	NA
WP_000073946.1\|1358648_1359086_+	hypothetical protein	NA	NA	NA	NA
WP_000908820.1\|1359129_1361355_-	cell division protein FtsK	S5VNE3	Mycobacterium_phage	2.8e-85	50.4
WP_000701411.1\|1361521_1363471_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_000640794.1\|1363467_1364379_-	1-phosphofructokinase	NA	NA	NA	NA
WP_000920629.1\|1364375_1365116_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_000756234.1\|1367252_1368176_-	hypothetical protein	NA	NA	NA	NA
WP_164925562.1\|1368811_1370159_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.8e-63	51.1
WP_000969965.1\|1370474_1370618_-	hypothetical protein	Q708R7	Streptococcus_phage	7.4e-16	93.6
WP_000090697.1\|1370777_1371566_+	helix-turn-helix domain-containing protein	Q708R9	Streptococcus_phage	2.1e-88	65.2
WP_161970158.1\|1371591_1372662_+	hypothetical protein	A0A141E0C6	Streptococcus_phage	9.1e-183	90.7
WP_001001539.1\|1373772_1374369_+	hypothetical protein	O21991	Streptococcus_virus	2.7e-19	42.4
WP_000290661.1\|1376294_1376930_-\|holin	1-alkyl-2-acetylglycerophosphocholine esterase	NA	NA	NA	NA
WP_000152854.1\|1376931_1377759_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_001189738.1\|1377780_1379100_-	CapA family protein	A0A0N9SJ77	Staphylococcus_phage	6.2e-32	28.3
WP_001272956.1\|1379516_1380128_+	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-16	42.4
WP_000855745.1\|1380172_1380901_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000272320.1\|1380940_1381852_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	4.5e-90	51.5
WP_000926599.1\|1381917_1382142_-	DUF4059 family protein	NA	NA	NA	NA
WP_000590982.1\|1382219_1382963_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-29	40.5
WP_001103449.1\|1382962_1383763_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000889097.1\|1383920_1384277_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.7e-33	56.4
WP_001170334.1\|1384282_1384801_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	5.4e-48	56.2
WP_000405836.1\|1384800_1385295_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.2e-41	52.1
WP_000648279.1\|1385429_1385876_+	DUF1836 domain-containing protein	NA	NA	NA	NA
WP_001098000.1\|1385872_1386520_+	hemolysin III family protein	NA	NA	NA	NA
WP_000689963.1\|1386540_1387122_-	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT	NA	NA	NA	NA
WP_000138516.1\|1387122_1387998_-	pyridoxal 5'-phosphate synthase lyase subunit PdxS	NA	NA	NA	NA
WP_000036782.1\|1388149_1389526_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_001131397.1\|1389833_1390757_+	FAD:protein FMN transferase	NA	NA	NA	NA
WP_000040035.1\|1390816_1391422_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.2e-54	55.0
WP_000673653.1\|1391440_1392685_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	1.7e-55	52.7
WP_000371280.1\|1392800_1393058_-	DUF896 family protein	NA	NA	NA	NA
WP_000164740.1\|1393099_1395136_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_000038753.1\|1395347_1396265_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_000659146.1\|1396450_1397122_-	hypothetical protein	NA	NA	NA	NA
WP_000361602.1\|1402721_1404113_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_000003914.1\|1404202_1405393_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	5.1e-142	66.4
WP_000010998.1\|1405898_1407242_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	1.0e-50	32.4
WP_000670818.1\|1407534_1408350_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_000974074.1\|1408401_1410582_-	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_000163009.1\|1410818_1411985_+\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_000625552.1\|1412321_1413248_-	ABC transporter permease	NA	NA	NA	NA
WP_000022265.1\|1413240_1413933_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	2.0e-29	34.3
WP_142359004.1\|1413950_1415046_-	peptide chain release factor 2	NA	NA	NA	NA
WP_000163010.1\|1415242_1416409_+\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	4.8e-12	22.9
1423106:1423123	attR	NA	NA	NA	NA

DBSCAN-SWA_9

1422686 : 1428969

Streptococcus_phage(33.33%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000613465.1\|1422686_1423277_-\|protease	ATP-dependent Clp protease proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	6.1e-56	55.6
WP_000515974.1\|1423450_1424080_-	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_000163009.1\|1424284_1425451_+\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_000136973.1\|1425724_1426192_-	dCMP deaminase	A7KUY9	Bacillus_phage	8.9e-34	57.6
WP_000004134.1\|1426210_1426768_-	TetR/AcrR family transcriptional regulator	A0A1X9I6A2	Streptococcus_phage	3.0e-20	62.5
WP_000219921.1\|1426892_1427738_+	DegV family protein	A0A1X9I5J4	Streptococcus_phage	4.3e-103	69.1
WP_012972544.1\|1427796_1428969_+	NAD(P)/FAD-dependent oxidoreductase	A0A2H4PQX1	Staphylococcus_phage	1.5e-16	56.6

DBSCAN-SWA_10

1535467 : 1624970

Streptococcus_phage(36.84%)

tRNA,protease,transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000163009.1\|1535467_1536634_+\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_161683683.1\|1537027_1538374_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	6.3e-56	31.2
WP_000565232.1\|1538389_1538755_-	VOC family protein	NA	NA	NA	NA
WP_000777771.1\|1538747_1539935_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000747180.1\|1539931_1540420_-	DUF5590 domain-containing protein	NA	NA	NA	NA
WP_000908499.1\|1540606_1541803_-	MFS transporter	NA	NA	NA	NA
WP_000039607.1\|1542194_1542743_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_000682781.1\|1542975_1551969_-	G5 domain-containing protein	NA	NA	NA	NA
WP_001245188.1\|1552178_1553663_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000697767.1\|1553714_1554443_-	peroxide stress protein YaaA	A0A1X9I5I0	Streptococcus_phage	7.6e-40	39.0
WP_001042484.1\|1554700_1561864_-	glycoside hydrolase family 2	L0N6M2	Herpes_simplex_virus	5.4e-13	24.9
WP_000436570.1\|1562222_1563479_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	1.2e-215	90.2
WP_012972561.1\|1563750_1564953_+\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	6.6e-198	86.5
WP_000515824.1\|1565406_1573719_-	beta-N-acetylglucosaminidase domain-containing protein	NA	NA	NA	NA
WP_001032521.1\|1573875_1580844_-	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_000697791.1\|1581202_1581931_-	peroxide stress protein YaaA	NA	NA	NA	NA
WP_000508267.1\|1582009_1582174_-	YczI family protein	NA	NA	NA	NA
WP_000821217.1\|1582238_1583834_-	hypothetical protein	NA	NA	NA	NA
WP_000412237.1\|1583845_1584256_-	peptide deformylase	A0A2I7R586	Vibrio_phage	7.8e-10	36.4
WP_000032423.1\|1584371_1587068_-	cation-translocating P-type ATPase	M1I547	Acanthocystis_turfacea_Chlorella_virus	2.4e-67	28.1
WP_000813926.1\|1587375_1588560_+	CDF family manganese efflux transporter MntE	NA	NA	NA	NA
WP_001279110.1\|1588596_1590468_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	7.1e-58	31.6
WP_001138828.1\|1590464_1591649_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	2.1e-39	32.2
WP_000027870.1\|1591660_1592428_-	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_000762183.1\|1592816_1593665_-	DegV family protein	NA	NA	NA	NA
WP_000521461.1\|1594110_1595463_-	phosphoglucosamine mutase	NA	NA	NA	NA
WP_001230939.1\|1595487_1596267_-	hypothetical protein	NA	NA	NA	NA
WP_161800677.1\|1596253_1597168_-	TIGR00159 family protein	NA	NA	NA	NA
WP_000080994.1\|1597248_1598217_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	1.2e-64	96.8
WP_000011281.1\|1598818_1599730_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	1.3e-153	98.7
WP_001231096.1\|1599726_1600704_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.9e-179	96.9
WP_000163060.1\|1600700_1601591_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	1.4e-06	30.6
WP_001140422.1\|1601642_1602023_-	RidA family protein	NA	NA	NA	NA
WP_000422594.1\|1602033_1602621_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_012972566.1\|1602629_1603862_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.9e-132	59.2
WP_000442260.1\|1603898_1604069_-	hypothetical protein	NA	NA	NA	NA
WP_000162455.1\|1604068_1604575_-	dihydrofolate reductase	G3MBI7	Bacillus_virus	3.0e-27	42.5
WP_033689158.1\|1604706_1605225_-	DNA starvation/stationary phase protection protein	NA	NA	NA	NA
WP_012972567.1\|1605457_1607068_-\|holin	choline binding-anchored murein hydrolase LytC	NA	NA	NA	NA
WP_000087894.1\|1607101_1607860_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_000221586.1\|1607957_1608635_-	DnaD domain-containing protein	A0A1X9I617	Streptococcus_phage	1.1e-05	50.0
WP_001122725.1\|1608643_1609588_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_001049318.1\|1610013_1610526_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	4.1e-32	48.0
WP_001287228.1\|1610611_1611370_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_001085675.1\|1611891_1612581_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_001085807.1\|1612787_1613213_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_000747758.1\|1613450_1614167_-	D-alanyl-D-alanine carboxypeptidase family protein	NA	NA	NA	NA
WP_000335623.1\|1614169_1614640_-	HIT family protein	NA	NA	NA	NA
WP_001077252.1\|1614641_1615679_-	M42 family metallopeptidase	NA	NA	NA	NA
WP_001074580.1\|1615882_1617208_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_000659158.1\|1617378_1617666_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	3.5e-09	31.2
WP_000078128.1\|1617871_1618450_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_000207301.1\|1618503_1619904_-	dipeptidase PepV	NA	NA	NA	NA
WP_000670178.1\|1619917_1620523_-	nitroreductase family protein	NA	NA	NA	NA
WP_000714621.1\|1620694_1621495_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001015753.1\|1621560_1622394_-	metallophosphoesterase family protein	NA	NA	NA	NA
WP_012972569.1\|1622383_1624231_-	excinuclease ABC subunit UvrC	NA	NA	NA	NA
WP_001267194.1\|1624268_1624970_-\|protease	matrixin family metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_11

1757275 : 1768433

Streptococcus_phage(72.73%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001028144.1\|1757275_1758715_-	aminoglycoside O-phosphotransferase APH(2'')-Ia	A0A1X9I6C2	Streptococcus_phage	3.8e-285	100.0
WP_000393259.1\|1758715_1759108_-	GNAT family N-acetyltransferase	A0A0N7GFH7	Staphylococcus_phage	6.9e-72	100.0
WP_164925530.1\|1759088_1759286_-	hypothetical protein	E4ZFP3	Streptococcus_phage	6.8e-28	98.3
WP_072387101.1\|1759396_1759804_-	WYL domain-containing protein	A0A1B0RXM3	Streptococcus_phage	1.1e-59	98.3
WP_001096887.1\|1760623_1761418_-	aminoglycoside O-phosphotransferase APH(3')-IIIa	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
WP_000627290.1\|1761510_1762053_-	streptothricin N-acetyltransferase Sat4	A0A1B0RXL7	Streptococcus_phage	8.9e-94	100.0
WP_001255864.1\|1762049_1762958_-	aminoglycoside nucleotidyltransferase ANT(6)-Ia	E4ZFP8	Streptococcus_phage	2.0e-167	93.4
WP_000662263.1\|1762990_1763725_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	1.5e-141	100.0
WP_000228166.1\|1763705_1764575_-	nucleotidyltransferase domain-containing protein	A0A1X9I6C9	Streptococcus_phage	4.3e-159	95.8
WP_000301254.1\|1764929_1766501_-	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	1.5e-173	61.1
WP_000510187.1\|1766504_1766918_-	hypothetical protein	NA	NA	NA	NA
WP_050152857.1\|1766918_1768433_-	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	1.1e-157	55.4

DBSCAN-SWA_12

1853680 : 1931598

Staphylococcus_prophage(20.0%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000163003.1\|1853680_1854847_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9
WP_001245373.1\|1855174_1856374_-	ABC transporter permease	NA	NA	NA	NA
WP_000895282.1\|1856370_1857264_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.6e-20	29.6
WP_000961516.1\|1857498_1859904_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_164925532.1\|1860489_1861536_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.2e-27	32.0
WP_164925572.1\|1861806_1862256_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000868605.1\|1862260_1862680_-	hypothetical protein	NA	NA	NA	NA
WP_164925573.1\|1862707_1863334_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000185820.1\|1863347_1863911_-	ECF transporter S component	NA	NA	NA	NA
WP_000181384.1\|1864368_1864872_-\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_001148083.1\|1865064_1865895_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_000656559.1\|1865879_1867562_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-17	32.1
WP_000795928.1\|1867730_1868276_-	ECF-type riboflavin transporter substrate-binding protein	NA	NA	NA	NA
WP_001063590.1\|1868291_1869140_-	S-adenosyl-l-methionine hydroxide adenosyltransferase family protein	NA	NA	NA	NA
WP_000691695.1\|1869327_1870677_+	Trk system potassium transporter TrkA	NA	NA	NA	NA
WP_012972599.1\|1870680_1872120_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000260646.1\|1872416_1874732_-	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.3e-114	32.6
WP_000904583.1\|1874970_1876032_+	DNA polymerase IV	NA	NA	NA	NA
WP_000280783.1\|1876179_1877025_-	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_000717997.1\|1877085_1878975_-	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_001227293.1\|1879112_1880678_+	ABC transporter substrate-binding protein/permease	NA	NA	NA	NA
WP_000189492.1\|1880677_1881418_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	9.8e-27	37.9
WP_001130036.1\|1881623_1881839_-	hypothetical protein	NA	NA	NA	NA
WP_000952979.1\|1882635_1883886_-	threonine ammonia-lyase IlvA	NA	NA	NA	NA
WP_000290683.1\|1884000_1885023_-	ketol-acid reductoisomerase	NA	NA	NA	NA
WP_001253805.1\|1885240_1885717_-	acetolactate synthase small subunit	NA	NA	NA	NA
WP_000411735.1\|1885709_1887410_-	acetolactate synthase large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	1.3e-66	31.7
WP_000036677.1\|1887610_1889278_-	DAK2 domain-containing protein	NA	NA	NA	NA
WP_000216437.1\|1889280_1889646_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_001140948.1\|1889801_1889990_-	50S ribosomal protein L28	NA	NA	NA	NA
WP_000163003.1\|1890212_1891379_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9
WP_000163004.1\|1891770_1892937_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9
WP_000725708.1\|1893209_1893884_-	hypothetical protein	NA	NA	NA	NA
WP_000776602.1\|1893888_1894335_-	response regulator transcription factor	NA	NA	NA	NA
WP_000800902.1\|1894448_1894952_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000428271.1\|1895047_1896808_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.7e-43	27.4
WP_000731786.1\|1896797_1898567_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.7e-38	25.2
WP_000360516.1\|1898550_1899012_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000532885.1\|1899189_1899906_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_001036258.1\|1900002_1901373_-	MATE family efflux transporter	NA	NA	NA	NA
WP_001085455.1\|1901487_1902642_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.4e-120	66.6
WP_000642685.1\|1902696_1903953_-	competence/damage-inducible protein A	NA	NA	NA	NA
WP_000239268.1\|1904030_1905086_-	LCP family protein	NA	NA	NA	NA
WP_000455529.1\|1905093_1905612_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000288245.1\|1905601_1906045_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_000413915.1\|1906140_1906770_-	competence protein	NA	NA	NA	NA
WP_000438298.1\|1906903_1907326_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	5.8e-24	44.5
WP_000228743.1\|1907433_1911111_-	DNA-directed RNA polymerase subunit beta'	R4TQM7	Phaeocystis_globosa_virus	3.1e-65	24.9
WP_000907176.1\|1911143_1914752_-	DNA-directed RNA polymerase subunit beta	A0A2P0VMZ3	Tetraselmis_virus	1.5e-40	26.1
WP_001232748.1\|1915200_1919097_+	pullulanase	NA	NA	NA	NA
WP_000229797.1\|1919197_1920247_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
WP_000334313.1\|1920469_1922278_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	3.3e-100	38.9
WP_000943496.1\|1922470_1923850_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_000814057.1\|1923948_1925802_-\|tRNA	proline--tRNA ligase	A0A2K9L297	Tupanvirus	5.7e-07	26.8
WP_000900678.1\|1925814_1927074_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_000189852.1\|1927095_1927899_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_000466723.1\|1927907_1928666_-	isoprenyl transferase	R9W0U9	Flavobacterium_phage	2.3e-23	47.5
WP_000163009.1\|1928871_1930038_+\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_000160547.1\|1930431_1931598_+\|transposase	IS30-like element ISSmi3 family transposase	H7BWC8	unidentified_phage	6.9e-11	25.0

DBSCAN-SWA_13

1962756 : 2017758

Staphylococcus_prophage(30.0%)

tRNA,protease,transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000163009.1\|1962756_1963923_+\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6
WP_000725966.1\|1964256_1964883_-	phosphoribulokinase	NA	NA	NA	NA
WP_001064215.1\|1964879_1965470_-	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	2.2e-53	56.5
WP_000423404.1\|1965462_1965969_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000521615.1\|1966012_1966153_-	hypothetical protein	NA	NA	NA	NA
WP_000560895.1\|1966164_1968372_-	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	5.3e-278	65.9
WP_000118112.1\|1968491_1970030_-	damage-inducible protein CinA	NA	NA	NA	NA
WP_000877345.1\|1970284_1971817_-	cardiolipin synthase	NA	NA	NA	NA
WP_164925533.1\|1971962_1972478_-	hypothetical protein	NA	NA	NA	NA
WP_000464297.1\|1972510_1973761_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_000017620.1\|1974116_1974422_-	DUF1292 domain-containing protein	NA	NA	NA	NA
WP_012972608.1\|1974437_1974857_-	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_000507059.1\|1974860_1975127_-	IreB family regulatory phosphoprotein	NA	NA	NA	NA
WP_000725123.1\|1975213_1975783_-	hypothetical protein	NA	NA	NA	NA
WP_000591165.1\|1975848_1976247_-	transcriptional regulator Spx	NA	NA	NA	NA
WP_000858856.1\|1976382_1979043_-	magnesium-translocating P-type ATPase	M1HLC0	Paramecium_bursaria_Chlorella_virus	4.9e-44	25.3
WP_001042889.1\|1979445_1980507_-	aminopeptidase P family protein	A0A0P0I8D7	Acinetobacter_phage	3.9e-21	27.1
WP_001152883.1\|1980499_1983331_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	5.2e-312	56.3
WP_000815623.1\|1983462_1984407_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_000078366.1\|1984418_1985096_+	DUF1129 domain-containing protein	NA	NA	NA	NA
WP_164925574.1\|1985388_1986420_+	LD-carboxypeptidase	NA	NA	NA	NA
WP_000166578.1\|1986587_1987151_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_000273417.1\|1987160_1987754_-	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_000018198.1\|1987769_1989719_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	8.5e-70	31.4
WP_000861978.1\|1989924_1990365_+	response regulator transcription factor	NA	NA	NA	NA
WP_000743981.1\|1990361_1990820_+	DUF3021 domain-containing protein	NA	NA	NA	NA
WP_000849614.1\|1990867_1991332_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	NA	NA	NA	NA
WP_164925575.1\|1991409_1991943_-	ABC transporter permease	NA	NA	NA	NA
WP_000278886.1\|1992000_1993287_-	response regulator transcription factor	NA	NA	NA	NA
WP_193334359.1\|1993298_1994945_-	sensor histidine kinase	NA	NA	NA	NA
WP_000532352.1\|1994946_1995561_-	DUF624 domain-containing protein	NA	NA	NA	NA
WP_000748388.1\|1995694_1996264_+	MptD family putative ECF transporter S component	NA	NA	NA	NA
WP_000444654.1\|1996293_1996986_-	ABC transporter permease	NA	NA	NA	NA
WP_000085672.1\|1996987_1998049_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.7e-29	35.7
WP_000231807.1\|1998041_1999415_-	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_000694521.1\|1999514_2000369_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000724974.1\|2000522_2001353_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000724947.1\|2001574_2002405_-	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000253939.1\|2002508_2002832_-	AzlD domain-containing protein	NA	NA	NA	NA
WP_001208222.1\|2002821_2003517_-	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_000720783.1\|2003894_2004560_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000572848.1\|2004675_2005539_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000655056.1\|2005642_2006653_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	NA	NA	NA	NA
WP_000569814.1\|2006642_2007080_-	ribosomal protein S18-alanine N-acetyltransferase	NA	NA	NA	NA
WP_000865730.1\|2007076_2007760_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_000162999.1\|2007951_2009118_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.7e-12	22.9
WP_000180844.1\|2009507_2009693_+\|bacteriocin	fratricide two-peptide bacteriocin subunit CibA	NA	NA	NA	NA
WP_000974050.1\|2009694_2009838_+\|bacteriocin	fratricide two-peptide bacteriocin subunit CibB	NA	NA	NA	NA
WP_000282493.1\|2010149_2010365_-	hypothetical protein	NA	NA	NA	NA
WP_000639590.1\|2010644_2010878_+	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_000331991.1\|2010879_2012559_+	ribonuclease J	NA	NA	NA	NA
WP_000220952.1\|2012698_2014612_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_001282936.1\|2015217_2016339_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000163009.1\|2016591_2017758_+\|transposase	IS30-like element ISSmi1 family transposase	Q9MBM9	Staphylococcus_prophage	6.3e-12	22.6

DBSCAN-SWA_14

2057586 : 2068441

Streptococcus_phage(88.89%)

integrase

attL 2055919:2055935|attR 2068447:2068463

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2055919:2055935	attL	NA	NA	NA	NA
WP_000824783.1\|2057586_2058090_-	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	1.1e-45	53.7
WP_000694570.1\|2058774_2058951_-	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	1.8e-08	58.6
WP_029692184.1\|2059275_2060958_-	DNA primase	A0A1X9I717	Streptococcus_phage	1.4e-270	86.1
WP_000158193.1\|2060935_2061796_-	replication protein	A0A1X9I6L2	Streptococcus_phage	3.4e-124	74.5
WP_165442198.1\|2061797_2061944_-	hypothetical protein	NA	NA	NA	NA
WP_000492147.1\|2061936_2062212_-	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	8.0e-27	62.5
WP_000058836.1\|2062204_2062546_-	hypothetical protein	NA	NA	NA	NA
WP_000122741.1\|2062526_2062820_-	hypothetical protein	NA	NA	NA	NA
WP_001003769.1\|2062816_2063032_-	hypothetical protein	NA	NA	NA	NA
WP_000171240.1\|2063033_2063234_-	hypothetical protein	NA	NA	NA	NA
WP_000382047.1\|2063230_2063662_-	hypothetical protein	A0A1X9I5T7	Streptococcus_phage	1.9e-54	69.7
WP_000424672.1\|2064096_2064723_-	Rha family transcriptional regulator	A0A192Y918	Salmonella_phage	1.4e-10	28.8
WP_000040968.1\|2064737_2064938_-	transcriptional regulator	NA	NA	NA	NA
WP_001080846.1\|2065143_2065569_+	helix-turn-helix transcriptional regulator	A0A1X9I723	Streptococcus_phage	2.1e-18	71.6
WP_000431494.1\|2065690_2067157_+	putative DNA binding domain-containing protein	NA	NA	NA	NA
WP_000704662.1\|2067274_2068441_+\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	9.6e-154	69.3
2068447:2068463	attR	NA	NA	NA	NA

DBSCAN-SWA_15

2123297 : 2132057

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000510420.1\|2123297_2124137_-	energy-coupling factor transporter ATPase	W8CYL7	Bacillus_phage	8.8e-16	32.1
WP_000835729.1\|2124121_2124949_-	energy-coupling factor transporter ATPase	G9BWD6	Planktothrix_phage	9.6e-23	32.9
WP_000712121.1\|2124945_2125491_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_001227988.1\|2125501_2126329_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_000170200.1\|2126370_2127654_-	insulinase family protein	A0A1E1EST3	Acanthamoeba_castellanii_mimivirus	6.5e-18	32.3
WP_000424258.1\|2127650_2128901_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	3.5e-93	42.8
WP_000455905.1\|2129059_2129428_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	1.8e-18	58.7
WP_000266700.1\|2129430_2130528_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_000073412.1\|2130578_2132057_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	9.8e-95	40.5

Anti-CRISPR protein detection

Acr_ID: NC_013853.1|WP_000756234.1|1367252_1368176_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_013853.1|WP_000969965.1|1370474_1370618_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_013853.1|WP_000756234.1|1367252_1368176_-|hypothetical-protein

1367252_1368176_-

307 aa aa

1322661-1416409

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_013853_1	Orphan	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	1412226-1412178	1

1. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to NC_013853 position: 1412226-1412178, mismatch: 1

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

NC_013853.1|WP_000969965.1|1370474_1370618_-|hypothetical-protein

1370474_1370618_-

47 aa aa

1322661-1416409

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_013853_1	Orphan	1.2\|879474\|49\|NC_013853\|CRISPRCasFinder	879474-879522	49	1412226-1412178	1

1. spacer 1.2|879474|49|NC_013853|CRISPRCasFinder matches to NC_013853 position: 1412226-1412178, mismatch: 1

cccacaacctagcttttagtatgagaaaaatgcgtgaaatcagtggaaa	CRISPR spacer
cccacaacctagcttttagtatgagaaaaacgcgtgaaatcagtggaaa	Protospacer
******************************.******************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_013853

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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