CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_017159	Yersinia pestis D182038 plasmid pPCP1, complete sequence	0 crisprs	NA	0	0	0	0
NC_017157	Yersinia pestis D182038 plasmid pCD1, complete sequence	0 crisprs	NA	0	0	2	0
NC_017160	Yersinia pestis D182038, complete sequence	5 crisprs	DEDDh,DinG,cas3,cas1,cas8f,cas5f,cas7f,cas6f,csa3	3	10	12	1
NC_017158	Yersinia pestis D182038 plasmid pMT1, complete sequence	0 crisprs	NA	0	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 6364

Yersinia_phage(100.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213403.1\|1054_1447_-	type III secretion system chaperone SycE/YerA	NA	NA	NA	NA
WP_002229754.1\|1640_2300_+	type III secretion system effector GTPase activator YopE	NA	NA	NA	NA
WP_002213360.1\|2439_2739_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_002224342.1\|2731_2974_-	type II toxin-antitoxin system ParD family antitoxin	NA	NA	NA	NA
WP_002213357.1\|3517_3691_+	hypothetical protein	NA	NA	NA	NA
WP_154020274.1\|3839_4076_-	hypothetical protein	NA	NA	NA	NA
WP_002213354.1\|4235_5201_-	ParB/RepB/Spo0J family plasmid partition protein	Q7Y3Y7	Yersinia_phage	3.1e-89	56.6
WP_002220902.1\|5197_6364_-	plasmid-partitioning protein SopA	Q7Y3Y6	Yersinia_phage	3.5e-196	85.3

DBSCAN-SWA_2

11327 : 67390

Enterobacteria_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002209743.1\|11327_12536_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002213004.1\|12942_13341_+	type III secretion system chaperone SycT	NA	NA	NA	NA
WP_002222515.1\|14045_14465_+	hypothetical protein	NA	NA	NA	NA
WP_116442925.1\|15213_15459_+\|transposase	transposase	NA	NA	NA	NA
WP_002229779.1\|15700_16930_-	type III secretion system effector YopM	NA	NA	NA	NA
WP_002229781.1\|17323_17533_-	hypothetical protein	NA	NA	NA	NA
WP_002212987.1\|18658_19579_-	type III secretion system translocon subunit YopD	NA	NA	NA	NA
WP_002212985.1\|19597_20803_-	type III secretion system translocon subunit YopB	NA	NA	NA	NA
WP_002222758.1\|20780_21287_-	type III secretion system chaperone SycD/LcrH	NA	NA	NA	NA
WP_002212981.1\|21299_22280_-	type III secretion system needle tip protein LcrV	NA	NA	NA	NA
WP_002212973.1\|22281_22569_-	type III secretion system chaperone LcrG	NA	NA	NA	NA
WP_002220918.1\|22610_23051_-	type III secretion system chaperone LcrR	NA	NA	NA	NA
WP_002212971.1\|23047_25162_-	SctV family type III secretion system export apparatus subunit LcrD	NA	NA	NA	NA
WP_002229791.1\|25148_25493_-	type III secretion system chaperone YscY	NA	NA	NA	NA
WP_002212969.1\|25489_25858_-	type III secretion system protein YscX	NA	NA	NA	NA
WP_002229794.1\|25854_26226_-	type III secretion chaperone SycN	NA	NA	NA	NA
WP_002212965.1\|26212_26491_-	type III secretion system gatekeeper subunit TyeA	NA	NA	NA	NA
WP_002212958.1\|26471_27353_-	SctW family type III secretion system gatekeeper subunit YopN	NA	NA	NA	NA
WP_002212955.1\|27550_28870_+	SctN family type III secretion system ATPase YscN	NA	NA	NA	NA
WP_002212952.1\|28866_29331_+	type III secretion system central stalk protein YscO	NA	NA	NA	NA
WP_002212950.1\|29330_30698_+	type III secretion system needle length determinant YscP	NA	NA	NA	NA
WP_002212948.1\|30694_31618_+	SctQ family type III secretion system cytoplasmic ring protein YscQ	NA	NA	NA	NA
WP_002212947.1\|31614_32268_+	SctR family type III secretion system export apparatus subunit YscR	NA	NA	NA	NA
WP_002212945.1\|32269_32536_+	SctS family type III secretion system export apparatus subunit YscS	NA	NA	NA	NA
WP_002212938.1\|32532_33318_+	SctT family type III secretion system export apparatus subunit YscT	NA	NA	NA	NA
WP_002212936.1\|33317_34382_+	type III secretion system export apparatus switch protein YscU	NA	NA	NA	NA
WP_002222527.1\|34957_35353_+	type III secretion system pilotin YscW	NA	NA	NA	NA
WP_002212931.1\|35476_36292_+	virulence regulon transcriptional activator VirF	NA	NA	NA	NA
WP_002229797.1\|36370_36469_+	type III secretion system protein YscA	NA	NA	NA	NA
WP_002212925.1\|36694_37108_+	type III secretion system chaperone YscB	NA	NA	NA	NA
WP_002212923.1\|37113_38937_+	SctC family type III secretion system outer membrane ring subunit YscC	NA	NA	NA	NA
WP_002212919.1\|38933_40193_+	SctD family type III secretion system inner membrane ring subunit YscD	NA	NA	NA	NA
WP_002212917.1\|40189_40390_+	type III secretion system co-chaperone YscE	NA	NA	NA	NA
WP_002212916.1\|40390_40654_+	type III secretion system needle filament protein YscF	NA	NA	NA	NA
WP_002229801.1\|40655_41003_+	type III secretion system chaperone YscG	NA	NA	NA	NA
WP_002212915.1\|40999_41497_+	T3SS polymerization control protein YopR	NA	NA	NA	NA
WP_002212914.1\|41497_41845_+	SctI family type III secretion system inner rod subunit LcrO	NA	NA	NA	NA
WP_002212912.1\|41851_42586_+	SctJ family type III secretion inner membrane ring lipoprotein YscJ	NA	NA	NA	NA
WP_002361471.1\|42585_43215_+	type III secretion system sorting platform protein YscK	NA	NA	NA	NA
WP_010981371.1\|43160_43826_+	SctL family type III secretion system stator protein YscL	NA	NA	NA	NA
WP_002212907.1\|44050_44398_+	type III secretion system exported negative regulator LcrQ/YscM1	NA	NA	NA	NA
WP_002213278.1\|46486_47893_-	T3SS effector protein-tyrosine-phosphatase YopH	NA	NA	NA	NA
WP_002213287.1\|49575_50442_-	type III secretion system effector acetyltransferase YopJ	NA	NA	NA	NA
WP_002213290.1\|50837_53036_-	type III secretion system effector protein kinase YopO/YpkA	NA	NA	NA	NA
WP_002229809.1\|53043_53493_-	hypothetical protein	NA	NA	NA	NA
WP_002213291.1\|54238_54478_-	hypothetical protein	NA	NA	NA	NA
WP_002213292.1\|55650_56529_-	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_002233140.1\|56509_56584_-	RepA leader peptide Tap	NA	NA	NA	NA
WP_002229817.1\|56825_57080_-	replication regulatory protein RepA	NA	NA	NA	NA
WP_002233137.1\|57217_57466_-	phospholipase	A0A1B2LRT6	Wolbachia_phage	9.2e-06	47.1
WP_002213294.1\|57882_58290_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	4.7e-07	29.2
WP_002213244.1\|58313_58631_-\|transposase	transposase	NA	NA	NA	NA
WP_002213246.1\|58802_59261_-	hypothetical protein	NA	NA	NA	NA
WP_042469136.1\|59329_59599_+\|transposase	transposase	NA	NA	NA	NA
WP_002213256.1\|62210_64526_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	1.0e-279	51.6
WP_002213258.1\|64689_65241_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	5.9e-77	80.3
WP_002224338.1\|65259_65724_+	hypothetical protein	NA	NA	NA	NA
WP_002229829.1\|65862_66192_+	hypothetical protein	NA	NA	NA	NA
WP_086016640.1\|66291_67390_+\|transposase	IS3-like element ISYpe1 family transposase	S5WIU1	Leptospira_phage	1.4e-45	38.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_017160

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CRISPR-Cas detection and classification

Crispr_ID: NC_017160_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017160_1

1638716-1638837

Orphan

Consensus_repeat	Method
CTTAATGCCAATATTAATCGACATAATCAATTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017160_1

>merge|NC_017160|1|1638716-1638837|CRISPRCasFinder
CTTAATGCCAATATTAATCGACATAATCAATTGTAGTGGAGGGGGAGGATTGAGTTTTTTCCAAAAAAACATATTGCAGTATTAAATCTCTTAATGCCAATATTAATCGATATAATCAATTG

>NC_017160|1|1|1638716-1638837|CRISPRCasFinder
CTTAATGCCAATATTAATCGACATAATCAATTG	TAGTGGAGGGGGAGGATTGAGTTTTTTCCAAAAAAACATATTGCAGTATTAAATCT
CTTAATGCCAATATTAATCGATATAATCAATTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_017160.1\|WP_002213054.1\|1629178_1629496_-\|heat-shock-protein-HspQ	unknown	unknown	gnl\|CDD\|184526
NC_017160.1\|WP_002213025.1\|1644179_1644932_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|235936
NC_017160.1\|WP_002228570.1\|1645809_1646250_+\|lipocalin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|372819
NC_017160.1\|WP_002213052.1\|1629556_1630747_-\|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI	unknown	unknown	gnl\|CDD\|185082
NC_017160.1\|WP_002213038.1\|1637716_1638463_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180440
NC_017160.1\|WP_002221095.1\|1624899_1626954_+\|DNA-helicase-IV	unknown	unknown	gnl\|CDD\|182930
NC_017160.1\|WP_002213058.1\|1627657_1628338_-\|DUF2057-family-protein	unknown	unknown	gnl\|CDD\|179619
NC_017160.1\|WP_002213030.1\|1641474_1642212_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187594
NC_017160.1\|WP_002213039.1\|1635145_1637563_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366708
NC_017160.1\|WP_002213060.1\|1627014_1627479_-\|methylglyoxal-synthase	unknown	unknown	gnl\|CDD\|179969
NC_017160.1\|WP_002213032.1\|1640189_1641473_+\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	unknown	unknown	gnl\|CDD\|238430
NC_017160.1\|WP_002213046.1\|1631170_1631500_-\|sulfurtransferase-TusE	unknown	unknown	gnl\|CDD\|225472
NC_017160.1\|WP_002213024.1\|1644934_1645723_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NC_017160.1\|WP_002213036.1\|1639193_1639412_+\|hypothetical-protein	unknown	unknown	unknown
NC_017160.1\|WP_002213049.1\|1630840_1631119_+\|acylphosphatase	unknown	unknown	gnl\|CDD\|184675
NC_017160.1\|WP_014462326.1\|1643458_1644178_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|223955
NC_017160.1\|WP_002213017.1\|1646287_1646536_+\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|180851
NC_017160.1\|WP_002213034.1\|1639675_1640200_+\|beta-hydroxyacyl-ACP-dehydratase	unknown	unknown	gnl\|CDD\|223835
NC_017160.1\|WP_002213028.1\|1642227_1643466_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	unknown	unknown	gnl\|CDD\|225959
NC_017160.1\|WP_002213056.1\|1628653_1629070_+\|CoA-binding-protein	unknown	unknown	gnl\|CDD\|224745

Protein	Function_ID	Function_description	E-value
NC_017160.1\|WP_002213054.1\|1629178_1629496_-\|heat-shock-protein-HspQ	gnl\|CDD\|184526	PRK14129, PRK14129, heat shock protein HspQ; Provisional.	3.64231e-72
NC_017160.1\|WP_002221095.1\|1624899_1626954_+\|DNA-helicase-IV	gnl\|CDD\|182930	PRK11054, helD, DNA helicase IV; Provisional.	0
NC_017160.1\|WP_002228570.1\|1645809_1646250_+\|lipocalin-like-domain-containing-protein	gnl\|CDD\|372819	pfam13924, Lipocalin_5, Lipocalin-like domain. This family includes domains distantly related to lipocalins. However, they do contain the important GXW motif in the first strand. The protein in this family include aln5, which is involved in biosynthesis of alnumycin. The family also includes the ZFK protein from Trypanosoma brucei which is a protein kinase. This domain is at the C-terminus of that protein. The domain is also found as the C-terminal domain in StiJ a protein involved in producing stigmatellin. This domain has been assumed to catalyze a final cyclisation reaction.	5.67247e-46
NC_017160.1\|WP_002213052.1\|1629556_1630747_-\|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI	gnl\|CDD\|185082	PRK15128, PRK15128, 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI.	0
NC_017160.1\|WP_002213025.1\|1644179_1644932_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|235936	PRK07110, PRK07110, polyketide biosynthesis enoyl-CoA hydratase; Validated.	2.57932e-133
NC_017160.1\|WP_002213038.1\|1637716_1638463_-\|SDR-family-oxidoreductase	gnl\|CDD\|180440	PRK06172, PRK06172, SDR family oxidoreductase.	1.01866e-70
NC_017160.1\|WP_002213034.1\|1639675_1640200_+\|beta-hydroxyacyl-ACP-dehydratase	gnl\|CDD\|223835	COG0764, FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases [Lipid metabolism].	1.09929e-42
NC_017160.1\|WP_002213058.1\|1627657_1628338_-\|DUF2057-family-protein	gnl\|CDD\|179619	PRK03641, PRK03641, DUF2057 family protein.	4.09411e-122
NC_017160.1\|WP_002213030.1\|1641474_1642212_+\|SDR-family-oxidoreductase	gnl\|CDD\|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	2.26541e-68
NC_017160.1\|WP_002213039.1\|1635145_1637563_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366708	pfam01565, FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.	1.41205e-31
NC_017160.1\|WP_002213060.1\|1627014_1627479_-\|methylglyoxal-synthase	gnl\|CDD\|179969	PRK05234, mgsA, methylglyoxal synthase; Validated.	2.55286e-93
NC_017160.1\|WP_002213046.1\|1631170_1631500_-\|sulfurtransferase-TusE	gnl\|CDD\|225472	COG2920, DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism].	2.4785e-71
NC_017160.1\|WP_002213024.1\|1644934_1645723_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.49415e-40
NC_017160.1\|WP_002213032.1\|1640189_1641473_+\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	gnl\|CDD\|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	2.93328e-136
NC_017160.1\|WP_002213049.1\|1630840_1631119_+\|acylphosphatase	gnl\|CDD\|184675	PRK14426, PRK14426, acylphosphatase; Provisional.	1.02172e-54
NC_017160.1\|WP_014462326.1\|1643458_1644178_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|223955	COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism].	3.70829e-35
NC_017160.1\|WP_002213017.1\|1646287_1646536_+\|acyl-carrier-protein	gnl\|CDD\|180851	PRK07117, PRK07117, acyl carrier protein; Validated.	4.77778e-09
NC_017160.1\|WP_002213028.1\|1642227_1643466_+\|hydroxymethylglutaryl-CoA-synthase-family-protein	gnl\|CDD\|225959	COG3425, PksG, 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism].	1.57028e-141
NC_017160.1\|WP_002213056.1\|1628653_1629070_+\|CoA-binding-protein	gnl\|CDD\|224745	COG1832, COG1832, Predicted CoA-binding protein [General function prediction only].	1.53332e-71

>NC_017160.1|WP_002213038.1|1637716_1638463_-|SDR-family-oxidoreductase
MKKTILITGALSGIGNTATKLFSEMGYNVVFSGRRPEEGRVILDDLKRINKDVLYVNADMNSESDIKHLIEMTLERFGSLDVAVNCAGTVGETAEIQAVTQDNFHLVFNTNVLGTLLAMKYQIPVMVERGKGSIINISSIAGLVGLPSTGIYVASKHAIEGLTKTAALEVATTGVRINSISPGPVEGKMFDRFLGHDENNKKAFIEMMPNKRFTTQEEVAHTIVFLAEDNVTAITGQTITIDGGYTAQ
>NC_017160.1|WP_002213039.1|1635145_1637563_-|GNAT-family-N-acetyltransferase
MTTTLDIINSAKDLDPAEYRAFFLQSKAPLFYDLRFLIAAEQSPLLNVSKIFYLLARDEGRLIALVPLYLQEFRSADPLGLLISSAKLSIESEERGLFSHIIHCTDTTIPTLSHDPSLYARIFDAITAIAQAELARYFCFLNVQDGVLLREAQRNGLNINYMVDKFSIELDAFPDFDSFAQALPKYRRYEMVRQLRIFNRSDAKVRILAPPFDNEIEKLARLYYLTTQRLGTPYYWPESQLAVFCRLCGDLVRLIVVEQNGQIVSGFICFEEDGALHFWSAGMDDESSDFSPYTLGVSAVYRYAFEKGINLIECGRLNSHIKTRLGFKPKRLYSIVSQDLGIPAATQTSLSQLKLASQLDGEVRLASHPAFDEWYLTSVWNGRGPTRRPAGIVRAATEADVIRTIVFAKERGMEVSVRGSGHNYVGCFLRVDTLMLDISGLKGLDIDSRHKRAIVESGVSSGQLCHALAAKGLAFPTGHVKEVGISGFLLGGGLGINCSQWGGMSVFNVQALDIVTADGHLRHVSETQEPDLFWAARGAGPCSFFVVTRFYLSCYSLPRVITNSLYTLPFTYLHDLLARLEDASPPTNLQVMVSVSPPTSGDTPAVLLNILAFTDSPQEAQALCESFETRLELPLTALAINQPSNFETIYEQFSSMVVSKRFYADNILTDNTQELVSILSRYLSDAPSRGALTTIFWRGVTTYPQAAFSAHGKFFVSTYAQWDDAKDDSVNKYWLKRMYDELQEIARSRYINEYDLETRAGETSKCFAAENWERLQRLRLEYDPDGVFVDVQQLEEHGDQPGANN
>NC_017160.1|WP_002213046.1|1631170_1631500_-|sulfurtransferase-TusE
MLEFEGRIIDTDAQGYLKNSTDWSEALAPVLAEQEGITLTEPHWEVVRFVRAFYQEFNTSPAIRMLVKAMAQKYGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCI
>NC_017160.1|WP_002213049.1|1630840_1631119_+|acylphosphatase
MSKIYIVAYVYGVVQGVGFRYSTQRQAQQLGVTGYAKNCDDGSVEVVASGNPQAVERLMEWIRQGGPRGARVDRLLTEPYPPTPFETFSIRY
>NC_017160.1|WP_002213052.1|1629556_1630747_-|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI
MTVRLILAKGREKSLLRRHPWIFSGAVQRLEGDALSGETIDILDSQGKWLARAAYSPESQILARVWTFQQDEVIDCAFFIRRLQQAQNWRDWLAQRDGLNGYRLIAGESDGLPGITIDRFQNFLVLQLLSAGAEYQRETLVSALQHCYPECSIYDRSDVSVRKKEGLPLTQGLICGEMPPALLPISENGMQLFVDIQQGHKTGFYLDQRDSRLAARNYANGRRVLNCFSYTGAFAVAALMGNCQQVISVDTSQSVLDIAKQNIELNQLDLSKTEFVRDDVFQLLRSYRAQGEKFDLIIMDPPKFVENKSQLASACRGYKDINMLAIQLLRPGGILLSFSCSGLMPVDLFQKILADAALDAGHDIQFIEQFRQAADHPVIAAYPEGLYLKGFACRVM
>NC_017160.1|WP_002213054.1|1629178_1629496_-|heat-shock-protein-HspQ
MIASKFGIGQQVRHSLHGYLGVVIDIDPEYSLAPPEPDEVANNKTLRSSPWYHVVIEDDDGQPVHTYLAEAQLTYEDVDAHPEQPSLDELAASIRHQLQAPHLRN
>NC_017160.1|WP_002213056.1|1628653_1629070_+|CoA-binding-protein
MHDKDIADILKKVKTIALVGASDIPSRPSYRVMAYLLQQGYQVTPVNPKLAGELLLGQLVYAELADIPHAIDMVDVFRNSDAAYCIAQDAIAIGAKVLWLQIGVINEQAAILATDAGLQVVMDRCPKIELPRLGLEKG
>NC_017160.1|WP_002213058.1|1627657_1628338_-|DUF2057-family-protein
MKLGLVAGMLAVCFSFSSVAMTLKLTPEIDLLVVDGKNMSGSLLKGADSLELNSGMHQILFKVIKPLPTDPLVLYSSPPLIVVFNAHNTRSVAIKLPVINTLRDGHQFSKNPLYQLIGDNGHPLSVRHDVLRQDHLNNSTTLETVMAAYNVGKYNASVPAFAAIPPSPVSAVPGTTIPVAGVNTPHKTASLQGENVTEQMLQYWFLQANPETQKRFLIWAKKQPIH
>NC_017160.1|WP_002213060.1|1627014_1627479_-|methylglyoxal-synthase
MELTTRTIAARKHIALVSHDHCKKSLLAWVMENRDLLAQHELYATGTTGNLVQKATGIDVHCLLSGPMGGDQEVGALISEKKIDILIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNRSTADFLIGSTLFSSEVTIAIPDYDRYMQQRLDLK
>NC_017160.1|WP_002221095.1|1624899_1626954_+|DNA-helicase-IV
MELKATSFGKHLSQHPYNRVRLLNAGIEVCGDKHQYLIPFNQLVSIQCKRGIVWGELEFELPQQKVVRLHGTEWQETQHFYHYLLGVWQQWSEEMSQVCAEVLHKQVESIKRIEQQDKWFKRSELGQIQVMIREAFSALPMPVERLAAFESCRADYECCLRWLQQGRHSVERCNQQWTARMLEEYQDFFQNVETSPLNASQSRAVVNGEDSVLVLAGAGSGKTSVLVARAGWLLRRNEALPEQILLLAFGRQAADEMNSRIKQRLGVDSIQAKTFHALALHIIQQGSRKTPVISKLESDSQARRALLIQHWQQQCSEKKAQAKGWREWLTDELEWDVADGDFWQDKRLAARLASRLERWVGLMRMYGGSQAEMIEQANDEVRDLFQKRIRLMAPLLKAWKTALKDEGAVDFSGLIHQAVNLLEKGRFVSPWKHVLVDEFQDISPQRAMLLAALRKQNKQTCLFAVGDDWQAIYRFSGAELSLTTAFSEHFGEGAECALDTTYRFNDRIGDIANRFIQQNPYQLKKPLNSLSKGNKKSVMILPDEQLEALLDKLSGFVKDGERILILARYHHLRPEVLQKAATRWPKLTIDFMTIHASKGQQADYVIIVGLHEGNDGFPAAARESVLEDVLLPPPEDFPDAEERRLLYVAITRAKHQVWLLQDTARPSIFVSQLSELGALVQRKP
>NC_017160.1|WP_002213036.1|1639193_1639412_+|hypothetical-protein
MYLLQQIELCPDQILHAWKISQNPQVSEVFEIEVVSSEEDAEEAVLFWKAYFSSLGETVIDGRHVGDTFSRF
>NC_017160.1|WP_002213034.1|1639675_1640200_+|beta-hydroxyacyl-ACP-dehydratase
MKNTELNFLKTNFLFNQDITNELNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPIYPGVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVNDQIVTVGKGEFHVF
>NC_017160.1|WP_002213032.1|1640189_1641473_+|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein
MSSDRIVITGVAINTPIGDTLDLVGNNLLSGKSAIGYWRNFDTSNIYSKIGGQIPEYDIEGKLHAFSNRIPDIVLSRAEKVFKQTTKGVQLSVLMAMEAWLDAGLFEHIIDPFDCGIICGGHNLSDKYLLDQQKIFSDEPEFIDAFSGLNSLDTDHSSSVAQVLNTKGFAYLVGGTCATGNIAIQTAINAIKVDKKQVVAVVCPMASFHPMMLHSLTILEAICYSQYQDTPTKASRPYDINRSGFLPSEGGAVLIFEQAEHAKNRGAKIYAELLGASVNSDANHLGDPSHEGQVRVIQDVLKKCNISPEQVDYVSAHATSTKLGDIVELKSIKRVFGSHAEKLIINAPKSLLGHTMWASGVVEAAIAIWQMRQGEFHQSHNIETLDPAVELNVCASGNVKKEVNIFLNNSFGMGGINSASLFSRYHG
>NC_017160.1|WP_002213030.1|1641474_1642212_+|SDR-family-oxidoreductase
MNLFISGGASGIGRSVVIAALSKGWNVGFSYHNNKEGAQQLLDIAVAEFPRQLCRAYQLDVIDSGAVEYVGDRLLVDFSNIDAVVCNAGIDLPGNLVSMTDEDWALVLNTNLTGTFYLIRYFLPLFLANKYGRIVTLSSLAKDGSSGQAAYAASKAGLVGLTKTTAKEYGHFGITANVVVPGLINTEIIGDDIKGIKNFFAQYAPVGRLGSPSEVAEAILFLVAKESSYVNGAVFNVTGGIDWVY
>NC_017160.1|WP_002213028.1|1642227_1643466_+|hydroxymethylglutaryl-CoA-synthase-family-protein
MNSIGIEKISIYPSSLALKLSELAQARGGDNKYIQESLMVIKRSLVPQWEDAVTLAVNSAKDMLNDQDRSDIGLFIIATESGLDQEKAISTWAHRYLGLPATCRVFELKSACHAGAAALKMAESWISSGLNRGKKVLLINVDISNNMICHGKMEYSLGAGAIALLISDNPVFAVIETGKSGIHTHEVTDVIRPLPWKEVAFDVEASLFSYMDGLENAFEEYCHQTPEARESTYFNYNLYHVPFPGISKEAHKVLLELQGLFGKEALATSFKQKVMPSLYYAQKIGATYCGSIFLSLFSLMVKAPEIKSGDRIGVYSYGSGSCAEYFSMQVGDQAVEIAQQQGAALDILLTQRKILDVAAYEQLENARSAQMQGKDYRLDGDNLQDWYTHHYSGSGLLILERIDNHLRRYRYA
>NC_017160.1|WP_014462326.1|1643458_1644178_+|enoyl-CoA-hydratase/isomerase-family-protein
MHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVSQFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQINTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRPYLEDIKLFNDEYADD
>NC_017160.1|WP_002213025.1|1644179_1644932_+|enoyl-CoA-hydratase/isomerase-family-protein
MKKIYLRKSDEGIAFMHINDPVNKNAIDDEFCLQLHGIVDTIKQDKTIKVLILVGLPDIFCTGGTEAFLQSLITHYKTNIEHEYANHLKHFLNIPIPVIAAMEGSATGGGLVLGLYADILVAAEESRYGMSFMNMGFTPGMGSTAMSKEAFGYYTGFEMMVTGNYIRGSELKGKCCFNYILPRAMVMEKAIELATSIAEKPRHSLELLKKYMSIDRRKMLEETSTIEAFMHHIAFNQSNIEQQIQDNYTG
>NC_017160.1|WP_002213024.1|1644934_1645723_+|SDR-family-oxidoreductase
MLNNLSEMTVLVTGGTKGIGRATVESFVKAGAKVYGTYFWGDNLDELENHFSQYLNRPVFLQADISDEEITTQLIEKIAQENKKIDILILNAAFAPQFKDTYKFRGLLDSIEHNSWPLITYIDCIKQHFGQYPGYVVAITSEGHRSCHITGYDYVAASKAVLETLTKYIGARENIIINCISPGVVDTEAFELVFGKKAQAFIRKFDPDFIVSPEAVGNVSVALCSGLMDAVRGQVITVDNGRMFTDNFTKWIDMIETNFIEK
>NC_017160.1|WP_002228570.1|1645809_1646250_+|lipocalin-like-domain-containing-protein
MSNPNRNLFLGRWKLESCIGNSGGIHIYPIGREPFGMLIYTEQYMMVFISSVERTQFSTEDIRAIPSEQIVADFPKFETYCGHYIVNHDEKIVTHFIDNSKIPNQIGTQFRRYFSFEHEKLVLKSIDSLLLNDESWLFELVWNKQE
>NC_017160.1|WP_002213017.1|1646287_1646536_+|acyl-carrier-protein
MDRDHIASIVKKHIVNSIDGAKEHEIDLQKSMADYGASSLDIVSVVSGVMRELKIKIPRTELKNIKSINGLIDLFVTSSSES

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Crispr_ID: NC_017160_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017160_2

1992932-1993141

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRT
ATTTTCTAAGCTGCCTGTGCGGCAGTGAACCT	PILER-CR

3 spacers

DEDDh

The CRISPR arrays of NC_017160_2

>merge|NC_017160|2|1992932-1993141|CRISPRCasFinder,CRT,PILER-CR
TTATTGGGCTGCCTGTGCGGCAGTGAACGTTATACCCCGCGCAGGGAGTGAAGCGTTGACTTTCTAAGCTGCCTGTGCGGCAGTGAACTTAAGTTCTTTTTGTCAGCATCTTTAATAAATTTTCTAAGCTGCCTGTGCGGCAGTGAACCTGAAATACAAATAAAATAAATCGTCGAACATTTTCTAAGCTGCCTGTGCGGCAGTGAACGT

>NC_017160|2|2|1992932-1993139|CRISPRCasFinder
TTATTGGGCTGCCTGTGCGGCAGTGAAC	GTTATACCCCGCGCAGGGAGTGAAGCGTTGAC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TTAAGTTCTTTTTGTCAGCATCTTTAATAAAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CTGAAATACAAATAAAATAAATCGTCGAACAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NC_017160|2|1|1992932-1993139|CRT
TTATTGGGCTGCCTGTGCGGCAGTGAAC	GTTATACCCCGCGCAGGGAGTGAAGCGTTGAC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TTAAGTTCTTTTTGTCAGCATCTTTAATAAAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CTGAAATACAAATAAAATAAATCGTCGAACAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NC_017160|2|1|1992992-1993141|PILER-CR
TTTCTAAGCTGCCTGTGCGGCAGTGAACTTAA	GTTCTTTTTGTCAGCATCTTTAATAAAT
TTTCTAAGCTGCCTGTGCGGCAGTGAACCTGA	AATACAAATAAAATAAATCGTCGAACAT
TTTCTAAGCTGCCTGTGCGGCAGTGAACGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_017160.1\|WP_157131899.1\|1999782_2000073_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374732
NC_017160.1\|WP_002216393.1\|1980691_1981432_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187626
NC_017160.1\|WP_002217522.1\|1989313_1989631_-\|DUF496-family-protein	unknown	unknown	gnl\|CDD\|180070
NC_017160.1\|WP_002231208.1\|2001430_2001478_+\|his-operon-leader-peptide	unknown	unknown	unknown
NC_017160.1\|WP_002216311.1\|1996861_1997755_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_017160.1\|WP_002216312.1\|1995484_1996576_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|182570
NC_017160.1\|WP_002211896.1\|2001760_2002660_+\|ATP-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234781
NC_017160.1\|WP_002216388.1\|1984619_1987772_+\|inverse-autotransporter-beta-barrel-domain-containing-protein	unknown	unknown	gnl\|CDD\|378762
NC_017160.1\|WP_002211917.1\|1978492_1979770_-\|L-fuconate-dehydratase	unknown	unknown	gnl\|CDD\|239440
NC_017160.1\|WP_002211898.1\|2000227_2001055_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187576
NC_017160.1\|WP_002211904.1\|1991466_1992897_+\|exodeoxyribonuclease-I	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|236979
NC_017160.1\|WP_002211916.1\|1979801_1980644_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NC_017160.1\|WP_002211902.1\|1993633_1995025_-\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NC_017160.1\|WP_002211905.1\|1990064_1991174_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187547
NC_017160.1\|WP_002211900.1\|1998398_1999394_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NC_017160.1\|WP_002209743.1\|1987734_1988943_-\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|225865
NC_017160.1\|WP_002211911.1\|1982290_1983595_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NC_017160.1\|WP_002216310.1\|1997712_1998402_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_017160.1\|WP_190947800.1\|1999658_1999772_+\|gluconate-5-dehydrogenase	unknown	unknown	unknown
NC_017160.1\|WP_002211912.1\|1981859_1982282_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556

Protein	Function_ID	Function_description	E-value
NC_017160.1\|WP_002216393.1\|1980691_1981432_-\|SDR-family-oxidoreductase	gnl\|CDD\|187626	cd05368, DHRS6_like_SDR_c, human DHRS6-like, classical (c) SDRs. Human DHRS6, and similar proteins. These proteins are classical SDRs, with a canonical active site tetrad and a close match to the typical Gly-rich NAD-binding motif. Human DHRS6 is a cytosolic type 2 (R)-hydroxybutyrate dehydrogenase, which catalyses the conversion of (R)-hydroxybutyrate to acetoacetate. Also included in this subgroup is Escherichia coli UcpA (upstream cys P). Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. Note: removed : needed to make this chiodl smaller when drew final trees: rmeoved text form description: Other proteins in this subgroup include Thermoplasma acidophilum aldohexose dehydrogenase, which has high dehydrogenase activity against D-mannose, Bacillus subtilis BacC involved in the biosynthesis of the dipeptide bacilysin and its antibiotic moiety anticapsin, Sphingomonas paucimobilis strain B90 LinC, involved in the degradation of hexachlorocyclohexane isomers...... P).	1.05065e-117
NC_017160.1\|WP_002217522.1\|1989313_1989631_-\|DUF496-family-protein	gnl\|CDD\|180070	PRK05423, PRK05423, DUF496 family protein.	5.26004e-59
NC_017160.1\|WP_002216311.1\|1996861_1997755_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	3.90601e-98
NC_017160.1\|WP_002216312.1\|1995484_1996576_-\|oxidoreductase	gnl\|CDD\|182570	PRK10586, PRK10586, putative oxidoreductase; Provisional.	0
NC_017160.1\|WP_002211896.1\|2001760_2002660_+\|ATP-phosphoribosyltransferase	gnl\|CDD\|234781	PRK00489, hisG, ATP phosphoribosyltransferase; Reviewed.	6.63843e-161
NC_017160.1\|WP_002216388.1\|1984619_1987772_+\|inverse-autotransporter-beta-barrel-domain-containing-protein	gnl\|CDD\|378762	pfam11924, IAT_beta, Inverse autotransporter, beta-domain. This is a family of beta-barrel porin-like outer membrane proteins from enteropathogenic Gram-negative bacteria. Intimins and invasins are virulence factors produced by pathogenic Gram-negative bacteria. They carry C-terminal extracellular passenger domains that are involved in adhesion to host cells and N-terminal beta domains that are embedded in the outer membrane. This family represents the beta-barrel porin-like domain in the outer membrane that can be found in intimins, invasins and some inverse autotransporters.	1.47456e-126
NC_017160.1\|WP_002211917.1\|1978492_1979770_-\|L-fuconate-dehydratase	gnl\|CDD\|239440	cd03324, rTSbeta_L-fuconate_dehydratase, Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to mediate the down-regulation of thymidylate synthase protein by a novel intercellular signaling mechanism. A member of this family, from Xanthomonas, has been characterized to be a L-fuconate dehydratase. rTS beta belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	0
NC_017160.1\|WP_002211898.1\|2000227_2001055_-\|SDR-family-oxidoreductase	gnl\|CDD\|187576	cd05266, SDR_a4, atypical (a) SDRs, subgroup 4. Atypical SDRs in this subgroup are poorly defined, one member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is related to, but is different from, the archetypical SDRs, GXGXXG. This subgroup also lacks most of the characteristic active site residues of the SDRs; however, the upstream Ser is present at the usual place, and some potential catalytic residues are present in place of the usual YXXXK active site motif. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.54107e-68
NC_017160.1\|WP_002211904.1\|1991466_1992897_+\|exodeoxyribonuclease-I	gnl\|CDD\|236979	PRK11779, sbcB, exonuclease I; Provisional.	0
NC_017160.1\|WP_002211916.1\|1979801_1980644_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	8.96038e-107
NC_017160.1\|WP_002211902.1\|1993633_1995025_-\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	3.72025e-45
NC_017160.1\|WP_002211905.1\|1990064_1991174_-\|SDR-family-oxidoreductase	gnl\|CDD\|187547	cd05236, FAR-N_SDR_e, fatty acyl CoA reductases (FARs), extended (e) SDRs. SDRs are Rossmann-fold NAD(P)H-binding proteins, many of which may function as fatty acyl CoA reductases (FAR), acting on medium and long chain fatty acids, and have been reported to be involved in diverse processes such as biosynthesis of insect pheromones, plant cuticular wax production, and mammalian wax biosynthesis. In Arabidopsis thaliana, proteins with this particular architecture have also been identified as the MALE STERILITY 2 (MS2) gene product, which is implicated in male gametogenesis. Mutations in MS2 inhibit the synthesis of exine (sporopollenin), rendering plants unable to reduce pollen wall fatty acids to corresponding alcohols. This N-terminal domain shares the catalytic triad (but not the upstream Asn) and characteristic NADP-binding motif of the extended SDR family. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.89947e-61
NC_017160.1\|WP_002211900.1\|1998398_1999394_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.22935e-72
NC_017160.1\|WP_002209743.1\|1987734_1988943_-\|IS256-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.39969e-152
NC_017160.1\|WP_002211911.1\|1982290_1983595_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.17308e-74
NC_017160.1\|WP_002216310.1\|1997712_1998402_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	1.76633e-90
NC_017160.1\|WP_157131899.1\|1999782_2000073_+\|hypothetical-protein	gnl\|CDD\|374732	pfam16695, Tai4, Type VI secretion system (T6SS), amidase immunity protein. Tai4 is a new form of autoimmunity protein for a type VI secretion system, T6SS. T6SS has roles in interspecies interactions, as well as higher order host-infection, by injecting effector proteins into the periplasmic compartment of the recipient cells of closely related species. Pseudomonas aeruginosa produces at least three effector proteins to other cells and thus has three specific cognate immunity proteins to protect itself. Tae4, or type VI amidase effector 4, in Enterobacter cloacae has a cognate Tai4 or type VI amidase immunity 4 protein. The effector is Tae4, pfam14113.	4.0065e-14
NC_017160.1\|WP_002211912.1\|1981859_1982282_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	5.0494e-57

>NC_017160.1|WP_002211904.1|1991466_1992897_+|exodeoxyribonuclease-I
MSDKNKQPTFYVHDYETFGQRPALDRPAQFAGVRTDLDFNLVEEPLVIYCKPADDYLPQPEAVMITGITPQHALANGVNEAEFSRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYDPYAYSWQGGNSRWDLLDVMRACYALRPEGIVWPENDDGLPSFKLEHLTKANGVEHLQAHDAMSDVYATIAMAKLVKQAQPRLFDYLYQHRSKHKINALIDIAEMTPLVHVSGMFGAARGNTSWVAPLAWHPENKNAVIMCDLAGDMSPLLELDSDTLRERLYTRRDKLQAQESAIPIKLVHINKCPVLAPAKTLLPENADRLGIDRQRCLQNLQLLRQNPQVREKVVALFAQAEPFAVTDDVDTQLYNGFFSDADRATIKIIQQTESQNLPALDLTFQDPRLEALLFRFRARNYPNTLNDSEQQRWLQHRREALSPERVQDYVLQLEQFYNQYEDDKEKLALLKALFEYAKGLVS
>NC_017160.1|WP_002211905.1|1990064_1991174_-|SDR-family-oxidoreductase
MKKLLLTGATGFLGGAVLEKLLLASSDFNYLLLVRANTPEQGLMRIRENLEKFYLPNELINKININHVLLGDLAEPDSFINDVRIDDVTHVINCAAIASFGNNPLIWKVNVEGTLAFGKRMAQVAGLQRFVHVGTAMACTPEADTVVDERVLSTENDAHLVEYTKSKSAIECLLAEHCPTLPLVFARPSIVVGHTRLGCQPSSSIFWVFRMALMLRKFMCSLDDHIDVIPVDYCADALLYILEYPNLPDDIYHISAGEKGSVSFSEIDQAMSVAAKQKPVGVNYSQVEYTALVQMRNQLKGIFGPCNERLMLKAMRLYGSFAMLNVRFSNERLLSLGMPRTPRFTDYIARCVESSHGMTIQQQMAVDFK
>NC_017160.1|WP_002217522.1|1989313_1989631_-|DUF496-family-protein
MDNASKPTFQDVLEFVRMFRRKNKLQREIVDNEKKIRDNQKRVLLLDNLSEYIKPGMSIEEVQAIIANMRGDYEDRVDDYIIKNADLSKERRELSKKLKAMGEVK
>NC_017160.1|WP_002209743.1|1987734_1988943_-|IS256-family-transposase
MDEKKLKALAAELAKGLKTEADLNAFSRMLTKLTVETALNAELTEHLGHEKNTPKSGSNTRNGYSSKTLLCDDGEIELNTPRDRENTFEPQLIKKNQTRITQMDSQILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDAVKEQVAEWQNRQLDALYPIVYMDCIVVKVRQNGSVINKAVFLALGINTEGQKELLGMWLAENEGAKFWLSVLTELKNRGLQDILIACVDGLKGFPDAINSVYPQTHIQLCIIHMVRNSLKYVSWKDYKAVTSGLKMVYQAPTEEAALMALDKFAEAWDDKYPQISKSWRTHWENLNTFFGYPPDIRKAIYTTNAIESVNSVIRAAIKKRKVFPTDDSVRKVVYLAIKDASKKWSMPIQNWRLAMSRFIIEFGDRLSDHL
>NC_017160.1|WP_002216388.1|1984619_1987772_+|inverse-autotransporter-beta-barrel-domain-containing-protein
MSLYRISSLHQAKQLNKNKQLNKTRISKSVVWANIVIQAIFPLSIAFTPAVMAAETVGASDEKPRSASQAEQSTANAATRLASILTNDDSAKQASSIARGTAANAGNEALQKWFNQFGSAKVQLNLDEKLSLKGSQLDVLLPLTDSPDLLTFTQLGGRYIDDRVTLNVGLGQRHFFAQQMLGYNLFIDHDASYSHTRIGVGAEYGRDFINLAANGYFGVSGWKNSPDLDKYDEKVANGFDLRSEAYLPTLPQLGGKLIYEQYFGDEVGLFGVDNRQKNPLAVTLGVNYTPIPLFTVGVDHKMGRAGMNDTRFNLGFNYAFGTPLTHQLDSDAVAIKRSLMGSRYNLVDRNNQIVMKYRKQNRVTLELPARVSGAARQTMPLVANATAQQGIDRLEWEASALTLAGGKITGSGNNWQITLPSYLSGGEGNNTYRISAIAYDTLGNASPVAYSDLVVDSHGVNTNASGLTAAPEILPANASASSVIEFNIKDNANQPITGIADELAFSLELVELPEELAKAKARSVPLKTVSHTLTKITESAPGIYQATLTSGSKPQLINITAQINGVPLADVQTKVTLIADESTATLQTSSLQIITNGSLADDTDANQIRAVVVDAYGNKLSGVQVNFTVGNNAKITETTLSDKQGGVTAAITSTKAGTYTVTAELNGVTQQIDVNFIPDAGTATLDDSDEYKLQWVTNGQVADGESTNSVQLTVVDKFGNTVPGVDVAFTTDIGAIISEVTPTDANGVATAKIISSQAKSHTVKATLNRKEQTVEVNFIADTATAEITANNFTVEVDGQVAGSGTNQVQALVVDKKGNPVANMTVNFTATNGVVVETTSAKTDENGKVTTNLSMTNVGGTISTVTATMINSANVTSTQDKPVIFYPDFTKATLNTPANTYSGFNINSGFPTTGFKNTHFQLSPHGITGANSDYDWVSSHPNVSVSNTGAITLQDNPGGKVTITATWKHDSSKVFTYDFTLNYWVGLYSSTNLSWAQANASCINAGMRLPTNREVSAGQDVRGVGSLLSLSIILCNCHRIKGDRSGGHRTR
>NC_017160.1|WP_002211911.1|1982290_1983595_-|MFS-transporter
MSNFNHYPDPTLNSAIKKAWYRLMPLMFIMYFVAFIDRINVGFAKDAMSADIGLSQSAFALGAGIFFAAYALFGIPANLMMNKLGAKVWLSSTTVVWGLLSAGTGLVSNEYQFVILRFLLGVAEAGFYPGILLLASIYFPNKIRASVIGIFVLGVPAALTLGSPISGALLDMQGFLGQPGWFWMFLLEGLPAVGLGIFAFFYLDDSPATARYLNPEEKQALLTQLSIEQSDTESSSVKAVLLSPKVWHLALIYGTIQVGVYGLIFFLPSQVATLLGSTLGFKESLVAAIPWAFSALGVYYIPRYADRKTHRRNPIATLNLVVAAIGLIISAYASPVLAIAALCLCAIGFLAVQPIFWTFPAQILSGKALAAGIGFCTTMGAFFSFLAPIIRVEAESQFNSPPAGLITLALFSLLSATLIFSLKFWPAKATAEVI
>NC_017160.1|WP_002211912.1|1981859_1982282_+|thiol-disulfide-oxidoreductase-DCC-family-protein
MSAPLPYIKPGERVIIYDGVCALCTGWVNFLIRHDRRHTVRLSAVQSKKGHALLEWAGLPTDKINTLVLIENQQVYLRSEAIFRVIANLPWPWRILGVLRIFPRPLRDRCYDGIALNRYRLFGRYDAVRKLKADHERRFL
>NC_017160.1|WP_002216393.1|1980691_1981432_-|SDR-family-oxidoreductase
MNLKGKKALVTAAGQGIGFNTATLFARKGAEVIASDINIAALSNIPGITAVSLDVTDTLAINDVAQAIGPIDVLFNCAGVVHSGDILTCSEQEWQFALDLNVTAMFHMIRAFLPGMIACQQGSIINMSSVASSIKGVPNRFAYSTSKAAVIGLTRSVAADYVTQGIRCNAICPGTVESPSLRQRIAVQAHAEGRSEADVFQAFAARQPIGRIGKAEEIAQLALYLASDASAYTTGTIHIIDGGWSN
>NC_017160.1|WP_002211916.1|1979801_1980644_-|fumarylacetoacetate-hydrolase-family-protein
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGEQRLGACVGHVGKFICVGLNYADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVKTDWEVELGVVIGTGGRYIGEANAMSYVAGYCVVNDISEREFQLEHGGTWDKGKGCDTFGPIGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVISTGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA
>NC_017160.1|WP_002211917.1|1978492_1979770_-|L-fuconate-dehydratase
MTIITALRTEDVRFPTSLELDGSDAMNPDPDYSAAYVILDTDNPALSGHGLTFTIGRGNEICCVAIHALEHLIVGRDLASMTANMGKFWREFTSDSQLRWIGPEKGAIHLATGAVINAVWDLWSKAEGKPLWRLVADMSPEELVRCIDFRYITDCITPEEALTLLQQRAHNKALRLEKLQDEGYPCYTTSAGWLGYPDDKLRRLCQDAVDAGFDYLKLKVGRDLEDDIRRVRITREVLGPDRKLMIDANQIWETNEAIPWVNQLAFANPWFIEEPTNPDDIEGHRRIRQGVAPVKVATGEMCQNRIMFKQFIMREAIDVVQIDACRLGGVNEVLAVMLMAAKYDLPVCPHAGGVGLCEYVQHLAMIDYLCIAGTDKGRVIEYVDHLHEHFVHPCVIKNAAYMPPEQPGFSIEMHQSSIEKYRFRV
>NC_017160.1|WP_002211902.1|1993633_1995025_-|APC-family-permease
MAHDATVAVGTNQTGTNNRVQLRKTLTLVQVVMMGLAYLQPMTIFDTFGIVSGLTDGHVATSYAIALIAVLFTAVSYGKLVKRFPSAGSAYTYAQKSISPNVGFMVGWSSLLDYLFMPMINILLAKIYLEAIFPGVPSWIFVGALVSLMTLFNLRGINIVANLNSVIVVVQVAIMVVFMGLLIHGVYQGEGAGTLVSARPFYSENAHLVPMITGATILCFSFLGFDGISSLSEETPNAGKVIPKAIFLTALIGGIIFIAVSYCLQLYFPDISRFTDPEASQPEIMLFVAGKFFQSVILCFSCVTVLASGMAAHAGVSRLLYVMGRDGVFPEKVFGYVHPKWRTPAINVLLVGGVALSAISFDLVTATALINFGALVAFTFVNLSVIAQFYVRERRNSTFKDHFNYLILPMIGAGTVGVLWVNLESSSMTLGLVWGAIGLSYMVWKTRAFRRALPQFTEEPAQL
>NC_017160.1|WP_002216312.1|1995484_1996576_-|oxidoreductase
MSANAIRVQVGPANYFSFPGAIDKLSEFYPQAALDKALWIYGERALAAAQDYLPKAFHGPQAVRAKFSTHCSQSTVADLVSAAGGDRQVVIGIGGGAVLDTAKVVARQLGVPLVAIPTIAATCAAWTPLSVWYNEAGQALNFEIFNDANHLVLVEPRIMLHAPVEYLLAGIGDTLAKWYEAVVLSPQPETLSLTVRLGLQAALEIRNVLLKQSEAALQAVAQGELTQDFLDVVDAIIAGGGMVGGLGERYTRVAAAHAVHNGLTLLPQTEHFLHGTKVAYGILVQTALLGQDEVLRSLIVAFNQLGLPTHLAALDVDINDREAIDRVIGRILKPGESIHYLPIALNSEKVWAAIEQVEIAAQH
>NC_017160.1|WP_002216311.1|1996861_1997755_+|sugar-ABC-transporter-ATP-binding-protein
MSSIPPSRLEMRNISISFSGFHALQEVDFTLEGGSTHALIGANGAGKSTLMAILSGAHNHYRGEIFIDGQPIDIHSPRQARQHGIHVVQQEVDVALIPTLSVAENIMLDELADRGHLFNWPQLYRQAEALLEQLELKLNVRQRLESCTLAEKQQVLLARALSHQCRFLILDEPTAPLDQEESARLFRVVRRLQSEGIGIVFISHRIHELREVCDQLTVLRDGRRVSHDTMEGMSGEQIVEKMLGHTLEDISPLGERQSAAKHGCRKHYCRKHCYRSAAYMISISCAISPSHYIRAKF
>NC_017160.1|WP_002216310.1|1997712_1998402_+|sugar-ABC-transporter-ATP-binding-protein
MRDISLTLHQGEILGIAGLAGAGKTELCKALFGDTPSTLERGELSGKAWRPRSPDRSVAQGLALVPEERRKEGIFIDEGIPMNLSVAADDSFSRWSLFSRRQELSWAKELIERLGIRTSSPQQKLAHLSGGNQQKVAIGKWLRGDAQVLIFDEPTKGVDIKAKQDLFSLIDQLAQQGKGIIYASGEFSELVGLCDRICVLWDGRIVAELNAAEVDEETLLLFSTGGTPQ
>NC_017160.1|WP_002211900.1|1998398_1999394_+|ABC-transporter-permease
MSKELPLPDVQPWRHQLFDFLYKWGMLLTVVALIALFGLASDNFLDPNNIINILRSIAIVTVIAIGVSISLSIGGFDLSVGSTASLANAVVVSLFVWYGFGTTGAIILTLLICTLVGLFNAFLIVVLKIPDMLATLASLFVIQGVAMTYSRGGSITQSMLLPSGDMAEGVIPEIFSALGQVPVIVLIMLAVTVVVQLYLSLTKHGRRMYAIGGNPQAARLAGIRTVRYRVLAYVLSAQLAALGGILLASRIGSSQVNAGSGYLMDAVAAAYIGFSLAGSGKPNAFGTLIGAIILGVLQNGLVMLSVPYYAMDIIKGLVLAMALALTYIQKR
>NC_017160.1|WP_190947800.1|1999658_1999772_+|gluconate-5-dehydrogenase
MDVFTASLRSACSLRRGHFVNNLTYLFNFFLYSCSRS
>NC_017160.1|WP_157131899.1|1999782_2000073_+|hypothetical-protein
MQQKNNLENFALSICLAEGFPDGEINSEAFSAVGAYVELGAYPVEAYEEVSELAKKFLEKKYISKNGESKLTVMKCIDLSQSSELSAIKDKYTRHI
>NC_017160.1|WP_002211898.1|2000227_2001055_-|SDR-family-oxidoreductase
MKKVAIIGLGWLGMPLAQSLSRRGIDVVGSKTTPDGVDAARMSGINCYPLVLTPELICEPDDLAQLMAVDALVITLPASRTTAGGDHYFQAVQQVVDSALAFGVPRIIFTSSTSVYGETRGRIKESSPLQPVTVAGKTLMALEQWLHQLPHTSVDILRLAGLVGTDRHPGRFLAGKTGVKGGSQGVNLVHQEDVIAAIELLLNRPKGGHLYNLCAPIHPRKRDFYPACARALQLTPPEFAVEEQEGANREIDGSKICSELGFEYLYPDPSRMPLN
>NC_017160.1|WP_002231208.1|2001430_2001478_+|his-operon-leader-peptide
MNRVQFNHHHHHHPD
>NC_017160.1|WP_002211896.1|2001760_2002660_+|ATP-phosphoribosyltransferase
MLDKTRLRIAMQKSGRLSDESQELLSRCGIKINLQQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGDDPRYFTLRRLDFGGCRLSLAAPLDAEYTGPQCLQDTRIATSYPHILKQYLDKQGVRFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMSVDKQQLIDRLMTRIQGVIQARESKYIMMHAPSERLDEIITLLPGAERPTILPLAGDKSRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME

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Crispr_ID: NC_017160_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017160_3

2839776-2840223

TypeI-F

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRT

7 spacers

cas1,cas8f,cas5f,cas7f,cas6f

The CRISPR arrays of NC_017160_3

>merge|NC_017160|3|2839776-2840223|PILER-CR,CRISPRCasFinder,CRT
GTTCACTGCCGCACAGGCAGCTTAGAAAGTCAGGAATTTATTCAACGTGTTGCAGACTCAGTTCACTGCCGCACAGGCAGCTTAGAAACTGATGGGTAACTTTAATCCCAAATTCTTTTTGTTCACTGCCGCACAGGCAGCTTAGAAATGTTAAATCGTCGCCTAAATTTGTTTGACCGAGTTCACTGCCGCACAGGCAGCTTAGAAAGTGGAATGGCTATTGCTATCGCTCGAGAATATGTTCACTGCCGCACAGGCAGCTTAGAAAATCTGCGCCAAAGAAAATGCCATTCAGATAATGTTCACTGCTGCACAGGCAGCTTAGAAAAACTACTAGAAGCTTGCCCATCTTACCTTTTCGTTCACTGCCGCACAGGCAGCTTAGAAAATCATGAAAGACATTGTTCGCCAGTCCCCTGAGTTCACTGCCGCACAGGCAATAATCAAA

>NC_017160|3|2|2839776-2840163|PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTCAGGAATTTATTCAACGTGTTGCAGACTCA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATGGGTAACTTTAATCCCAAATTCTTTTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGTTAAATCGTCGCCTAAATTTGTTTGACCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTGGAATGGCTATTGCTATCGCTCGAGAATAT
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATCTGCGCCAAAGAAAATGCCATTCAGATAAT
GTTCACTGCTGCACAGGCAGCTTAGAAA	AACTACTAGAAGCTTGCCCATCTTACCTTTTC
GTTCACTGCCGCACAGGCAGCTTAGAAA

>NC_017160|3|3|2839776-2840223|CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTCAGGAATTTATTCAACGTGTTGCAGACTCA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATGGGTAACTTTAATCCCAAATTCTTTTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGTTAAATCGTCGCCTAAATTTGTTTGACCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTGGAATGGCTATTGCTATCGCTCGAGAATAT
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATCTGCGCCAAAGAAAATGCCATTCAGATAAT
GTTCACTGCTGCACAGGCAGCTTAGAAA	AACTACTAGAAGCTTGCCCATCTTACCTTTTC
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATCATGAAAGACATTGTTCGCCAGTCCCCTGA
GTTCACTGCCGCACAGGCAATAATCAAA

>NC_017160|3|2|2839776-2840223|CRT
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTCAGGAATTTATTCAACGTGTTGCAGACTCA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATGGGTAACTTTAATCCCAAATTCTTTTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGTTAAATCGTCGCCTAAATTTGTTTGACCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GTGGAATGGCTATTGCTATCGCTCGAGAATAT
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATCTGCGCCAAAGAAAATGCCATTCAGATAAT
GTTCACTGCTGCACAGGCAGCTTAGAAA	AACTACTAGAAGCTTGCCCATCTTACCTTTTC
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATCATGAAAGACATTGTTCGCCAGTCCCCTGA
GTTCACTGCCGCACAGGCAATAATCAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017160.1\|WP_002210194.1\|2835176_2836292_+\|hypothetical-protein	unknown	unknown	unknown
NC_017160.1\|WP_002216551.1\|2852273_2852483_+\|hypothetical-protein	unknown	unknown	unknown
NC_017160.1\|WP_002210201.1\|2827074_2828463_-\|phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl\|CDD\|185312
NC_017160.1\|WP_002213840.1\|2834115_2835054_+\|DUF1861-family-protein	unknown	unknown	gnl\|CDD\|378102
NC_017160.1\|WP_002211861.1\|2852597_2853524_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
NC_017160.1\|WP_002210192.1\|2838193_2839438_-\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|223740
NC_017160.1\|WP_002210198.1\|2831186_2832062_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NC_017160.1\|WP_002210199.1\|2829791_2831078_+\|carbohydrate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224567
NC_017160.1\|WP_002211866.1\|2848579_2849134_+\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09674_cas6f_CAS-I-F	gnl\|CDD\|378224
NC_017160.1\|WP_002210200.1\|2828479_2829520_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380502
NC_017160.1\|WP_002210193.1\|2836330_2837605_+\|hypothetical-protein	unknown	unknown	unknown
NC_017160.1\|WP_002210191.1\|2840582_2841563_+\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|132676
NC_017160.1\|WP_002222491.1\|2845253_2846600_+\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	cd09675_cas8f_CAS-I-F	gnl\|CDD\|274203
NC_017160.1\|WP_002211864.1\|2850241_2850745_-\|formaldehyde-activating-enzyme	unknown	unknown	gnl\|CDD\|224708
NC_017160.1\|WP_002210197.1\|2832062_2832887_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NC_017160.1\|WP_002210196.1\|2833033_2834089_+\|glycoside-hydrolase-family-130-protein	unknown	unknown	gnl\|CDD\|350124
NC_017160.1\|WP_002211863.1\|2850791_2852150_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
NC_017160.1\|WP_002211868.1\|2846596_2847547_+\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	cd09676_cas5f_CAS-I-F	gnl\|CDD\|187807
NC_017160.1\|WP_002211867.1\|2847564_2848569_+\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09677_cas7f_CAS-I-F	gnl\|CDD\|378222
NC_017160.1\|WP_002211865.1\|2849211_2850231_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381305

Protein	Function_ID	Function_description	E-value
NC_017160.1\|WP_002211861.1\|2852597_2853524_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	3.26573e-51
NC_017160.1\|WP_002210201.1\|2827074_2828463_-\|phosphomannomutase/phosphoglucomutase	gnl\|CDD\|185312	PRK15414, PRK15414, phosphomannomutase.	0
NC_017160.1\|WP_002213840.1\|2834115_2835054_+\|DUF1861-family-protein	gnl\|CDD\|378102	pfam08950, DUF1861, Protein of unknown function (DUF1861). This hypothetical protein, found in bacteria and in the eukaryote Leishmania, has no known function.	6.29599e-176
NC_017160.1\|WP_002210192.1\|2838193_2839438_-\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	2.65074e-32
NC_017160.1\|WP_002210198.1\|2831186_2832062_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	2.26211e-58
NC_017160.1\|WP_002210199.1\|2829791_2831078_+\|carbohydrate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	2.85244e-50
NC_017160.1\|WP_002211866.1\|2848579_2849134_+\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|378224	pfam09618, Cas_Csy4, CRISPR-associated protein (Cas_Csy4). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	1.71931e-94
NC_017160.1\|WP_002210200.1\|2828479_2829520_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380502	cd06279, PBP1_LacI-like, ligand-binding domain of an uncharacterized transcription regulator from Corynebacterium glutamicum and its close homologs from other bacteria. This group includes the ligand-binding domain of an uncharacterized transcription regulator from Corynebacterium glutamicum and its close homologs from other bacteria. This group belongs to the LacI-GalR family repressors and are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding.	1.56156e-83
NC_017160.1\|WP_002210191.1\|2840582_2841563_+\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	0
NC_017160.1\|WP_002222491.1\|2845253_2846600_+\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|274203	TIGR02564, conserved_hypothetical_protein, CRISPR type I-F/YPEST-associated protein Csy1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2465 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy1, for CRISPR/Cas Subtype Ypest protein 1.	0
NC_017160.1\|WP_002211864.1\|2850241_2850745_-\|formaldehyde-activating-enzyme	gnl\|CDD\|224708	COG1795, COG1795, Formaldehyde-activating enzyme nesessary for methanogenesis [Energy production and conversion].	1.50048e-90
NC_017160.1\|WP_002210197.1\|2832062_2832887_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	4.72016e-69
NC_017160.1\|WP_002210196.1\|2833033_2834089_+\|glycoside-hydrolase-family-130-protein	gnl\|CDD\|350124	cd18612, GH130_Lin0857-like, Glycoside hydrolase family 130 such as Listeria innocua beta-1,2-mannobiose phosphorylase. This subfamily contains the glycosyl hydrolase family 130 (GH130), as classified by the carbohydrate-active enzymes database (CAZY), enzymes that are phosphorylases and hydrolases for beta-mannosides, and includes Listeria innocua beta-1,2-mannobiose phosphorylase (Lin0857). hey possess 5-bladed beta-propeller domains similar to families 32, 43, 62, 68, 117 (GH32, GH43, GH62, GH68, GH117). GH130 enzymes are involved in the bacterial utilization of mannans or N-linked glycans. Structure of Lin0857 shows beta-1,2-mannotriose bound in a U-shape, interacting with a phosphate analog at both ends. Lin0857 has a unique dimer structure connected by a loop, with a significant open-close loop displacement observed for substrate entry. A long loop, which is exclusively present in Lin0857, covers the active site to limit the pocket size.	9.75278e-165
NC_017160.1\|WP_002211863.1\|2850791_2852150_-\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.50877e-50
NC_017160.1\|WP_002211868.1\|2846596_2847547_+\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|187807	cd09676, Csy2_I-F, CRISPR/Cas system-associated RAMP superfamily protein Csy2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; predicted Cas5 ortholog.	1.12008e-157
NC_017160.1\|WP_002211867.1\|2847564_2848569_+\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
NC_017160.1\|WP_002211865.1\|2849211_2850231_-\|aldo/keto-reductase	gnl\|CDD\|381305	cd19079, AKR_EcYajO-like, Escherichia coli YajO and similar proteins. Escherichia coli YajO is the prototype of this family. It is an uncharacterized aldo/keto reductase family oxidoreductase.	6.34333e-143

>NC_017160.1|WP_002210192.1|2838193_2839438_-|mechanosensitive-ion-channel-family-protein
MQQRISQWLERLGMEFSDVMSLTMVIGLILLISVMIHLVLHRVVLAALQRRGQQSQRIWQQAITKHKLFQRVALLLQGIIINLQAVLWLQNGSQTQAVIVTAAQVWIMAFALLALFSLLDTLLALLRQSSVAHQLPLRGICQGLKLVAAIFIGIMIVSLLMGRSPLLLLSGLGAMTAVLMLVFKDPILGLVAGIQLSANDMLKIGDWLEMPKYGADGAVTDIGLTTVKVRNWDNTVTTIPTYALISDSFKNWRSMSESGGRRIKRSINIDTTSVHFLSEQEQQRLTLNPLLQHYLSEKSQELNQYNQQIALDLSSPLNGRRLTNIGTLRAYLVAYLRAHLGIHQSMTLMVRQLAPTPEGLPLEVYAFTNTTIWAEYEGIQADIFDHIFAVVSEFDLRIHQTPSGNDMRSMLAKV
>NC_017160.1|WP_002210193.1|2836330_2837605_+|hypothetical-protein
MKLLNTLVCIIGLTSFSSSAKLVNAEHLDALYQKVTVANKTELGLIHIYSEFPDYRWVKDPIEGVSAIDDVARAAIFYQRQYQATGSAADLEKVKSLVEFILYQRADNGYFYNFIYPDHSINKEYKTSVAEPNWWTWRALWALTQVYPTLVKTDNALAQRTRETIFATIDVIYKDFNFKQTRGEKEGVAVPEWLPHTAGDQASVLLMALSDAQALEAKPEIEKMMRSLAAGIMLMQVKDTSSPVNGAFLSWQNLWHGYGNSQAYALLVAGNRLGDRDMIKAAFNELDHFHPWLISNGLLNEFTVRQQGEKVTLIEQKKFSQIAYIIRPMVFANIKAWEISRDAVYLERAVDLSLWFFKNNPAQAQMYYPVTGIAFDGIDSATTVNKNSGAESTIEALLTLQLIESIPDAKRMLESALEKRNIKQ
>NC_017160.1|WP_002210194.1|2835176_2836292_+|hypothetical-protein
MKHKKYLPLFLMAGICSVAQADNSPDVVSANNMDNRTFFAGDKIRIVKDGGETIEAVVELSDDNIGIVRIPKDEKAYFHGNWLAEYKIEHFRNEGRSTNSRPVHEIVFADGRVNFGDTGWNTGFLLKQVRFTSDSRNESNHKVDFRMVEMEIRPAWSKSIDKHWFMFEGIYLGKTGYEKNRTTGGDNNIGGDGYGFRPYYRYQVSDRLSVNTDVKMLVEDKDARGADNGRFQFYEALVNVNYRVADNVHVGIEVFRKEGQDFNHNGTKTANVLEQELRPWVAWNMGKNNFLFKMEPQLRRIGGQDGYRETSKAQKYIFNYSYPIADRVYLVAEYFYRVEHDKKFWDRGVRDNKSYSDTTTHFGKLGINYIF
>NC_017160.1|WP_002213840.1|2834115_2835054_+|DUF1861-family-protein
MMRHAPPASVAQLFADYQKRTAHNTFSTGRLEFTGVGDKDVYNITAPFTSAGQVVIAGRVEARDSEHSTIVFFSEQQGQWAPVENAPTFQLQDPFFTRIEDELILGGVEINPHPDNPRQLIWHTVFFRGRDIHSLTRFASGPPGMKDIRLCHIQQGRIGVFTRPQGKIGGRGTIGYVEINNLEALTPETITSAELFEQQFNSEEWGGVNETHLLCDGTIGLLSHIACFDQHGRRHYYPGVFIFNPDTKNYTPIKIIAARDNFLPGATKRPDLVDVIFPGGLIVLPNNGWRLYVGASDAEAHWIDIEDPFSGF
>NC_017160.1|WP_002210196.1|2833033_2834089_+|glycoside-hydrolase-family-130-protein
MMRYSGNPLITPQDITPSHPGFKVECAFNAGITKLGDETIMLIRIAESVIPESEGITVVPLLMEISGHWQVTTRVFKHDDPAYDFSDPRLISDIADPSTVYLTSLSHLRVARSHDGVTFVVDDQPFIFPANGDEAFGCEDARITQIDGAYYINYSAVSAKGICTALAVTQDFTDVKRLGLIFCPDNRDACLFPEKINGKYMTLHRPAPKHFGKPEIWLASSLDLLHWGDHRHLLGTSQDPWDALKLGGGAQMLKTEKGWLQIYHGVDATQRYSLGALLLDLEQPTKILAKSPVPLLQPQAPYELHGFFGNVVFTCGALIENDSLRVYYGAADECMCLAEMPLAQLWQHLSV
>NC_017160.1|WP_002210197.1|2832062_2832887_+|carbohydrate-ABC-transporter-permease
MKKNINSLIIHLVMFSLALSWLYPYIWMVLSSFKQSADIYTTGLFGSAYSLDNYRFLFENSGRVEKPFLKTLFNSLFISTVVTVAVTLSSMFIGFALAKMQFKGQSLFRNLLFLQMVFPASMFIIPQFVLVRELGLLNTYSAMIVPFLMSSWGIFMISQSFQGTPNDYIHAAKIDNASLWQIMIYLMMPLNKAIIAIVALFTFVGTWDNFLWPLIVIQDESKMPLSVLLATFSKSYGVYVGPVIAGAVIQTIPIVVLFILFRKYFMQGMSLSLK
>NC_017160.1|WP_002210198.1|2831186_2832062_+|sugar-ABC-transporter-permease
MTFLKLKDKQVGSVLAASYLGYTSIFWFYPFIWLAVLSLTEWRFVGIPTFNGLNNFILVMQDPLFWKSMLNVMRFLMYYLPIVFISSFLFAFGLQKLKHGRTFVALSFLLANVSSGVAYSIVFSKIFSQNGPLNTFLYDWFGFTLPWLTSPDFAMLSIALVVTWKFVGYYGLILFSGLNSIPKEIYSAAELDNTRTIKRLFHITLPMINPQLIMVLVLAITVSFAIFTEPYLITGGGPLNSTTTPMIVMYETAFMKMQPSWAATMSIFIALISFGIILGVRKLLERKVEIV
>NC_017160.1|WP_002210199.1|2829791_2831078_+|carbohydrate-ABC-transporter-substrate-binding-protein
MLEKMKNTLISLAIASSCVVFTGCDNDTASAKNEKQDITLWIAPNNVQEAFWSEVVGEWNKQPDKKKVVFSTIPAAGSSEEAIMNAIASDRAPDISENIFTGFGSQLADLGQVVDLSTLDGYENLISTRQMTDIMDNWRYNGKNYILPIYMNPVLFWWRGDLLKEQGFSEVPKTYDEVYALSEKYTIPDKRYAIQATSGRNWWDRWFDFIALYYAQSDGKPYIANQQASYDNQAGRDVLDFMHTLFSKKWTLYDFGQDDPLVTGKVLGAVRGPWDISRYQQQYPEILKHIKMGPMLVKEQQDKPHTFADGKGLVLFSHSKVKPEAWEFIQWVFSQPKFDKRWMELTGMPPARADLLTNPFFAEYYQEHPYAAAYAEYVNVAIPPVSSGETVEIQRSMTQMIEKTAFNTATPDEALQQSIKEVNAILKP
>NC_017160.1|WP_002210200.1|2828479_2829520_-|LacI-family-DNA-binding-transcriptional-regulator
MTTGKKRETLKTIAETLNVTHTTVSNVFNRPEKVSPELREKILAYAESINYHGPAGAGRFLRTGKCGTLGVIFNDNLSYVFSDRHDIALMRGIAEECEKNGINIALMPLKTNNALKKRMMGALVDGYILNATYNNDEVVQAALTSGLPVITTDIKLQNFTCVSIDDGAAMQAICHHLLAAGHKKFGIVSFPVKRLPGELTSLAEFSTDYDNGVAFGRISACITALSDAGIDLHTSYVAEQPHSETGGEKAAKALLAKEPGISAIICLSDRFAFGVYQFCQDHNIPVPGQIAITGFDDIDIQDPPVGLTTIRQPTVLKGREAARALISGQLDNDISLDFELVVRDSA
>NC_017160.1|WP_002210201.1|2827074_2828463_-|phosphomannomutase/phosphoglucomutase
MEKLTCFKAYDIRGKLGSELNEEIAYRIGRAYCQWLKPAKVVVGGDARATSVELKNALAKGLMDGGADVIDIGMVGTEEVYFATRFYGVDGGIQVTASHNPIDYNGMKLVKKDAQPISGDNGLYEIQRLAQDNHFAPPGVRGQLETQLVREHYVEHLLSYIDLNALLPMKIVVNAGNGAAGPTLDALEAALAKRKVPISFIKINHQPDSSFPNGIPNPMLPENQWSTRQAVCEHQADLGIAWDGDFDRCFFFDHLGNFIEGYYIVGLLAEKFLLTNNMGKATHNTDKIIHDPRLTWNTIDIVQTLNGTAIESKTGHAFIKDAMRHHDAVYGGEMSAHHYFREFGYCDSGMIPWLLVIELLSKKTTSLFSLIESRKAKFPVSGELNFTVSDPKTKIQQIKQFYADSAIHVTGIDGLSMEFEHWRFNLRSSNTEPLVRLNIETRGDVTLLEQKTAQLTQLLYPK
>NC_017160.1|WP_002210191.1|2840582_2841563_+|type-I-F-CRISPR-associated-endonuclease-Cas1
MENAIHSSDLKTILHSKRSNIYYLEYCRVLVNGGRVEYVTDEGKQSLYWNIPIANTTVIMLGTGTSVTQAAMREFARAGVLVGFCGGGGTPLFAANDVEVNVSWLTAQSEYRPTEYLHDWVSFWFDDEKRLAAAVAFQRIRIAQIQQHWLSSHIQRESLFPVNHDQLLFILTRFEQNLANCLTSNDLMVQEAVLTKALYKLAANTVNYGDFTRAKRGGGIDLANRFLDHGNYLAYGLAATATWVIGLPHGLSVLHGKTRRGGLVFDVADLIKDALVLPQAFIAAMQGEEEQEFRQRCISGFQRTEALDVMIDGIKETAALCSQVPR
>NC_017160.1|WP_002222491.1|2845253_2846600_+|type-I-F-CRISPR-associated-protein-Csy1
MSDEGLAAFIVSYIKSREQPKLEAFDKEAEKRLAGLTQAEDIALAQQEIAQQRQELIARYEVRNWLTDAANRAGQIKLATHAPKYTHSDSKSSGILNIELQSKKKDYFSSVDLAEQASDVIGNAAVFDLVKLLQSECEGGSLIKCLEQGDNSVLKLFSNDDELVEEWTTKFKSILNNEKFTSHKLAKQFYFPVGPDQYHLLSPLFSSSLAQAMHQRIIEARFSDQSKEAKAAHKAGRWHPTVRVLYLDTAVQHIGGTKPQNISYLNSVRGGKVWLLPCGAPSWKNIQKPPIKYRSIFHDRSEFTVLARNNLWQMQLYLLGVKPLSNTMDIRAARLACCDEIIDILFNYVAEIQNLDGTNGWSDAEDCKLKRSEQLWLDPTRAMDDPVFKLEREKEDWKQEVSQDFGYWLNRWLQHDELVFGYVEQREWSSLFKQRLREFEQGSLETSS
>NC_017160.1|WP_002211868.1|2846596_2847547_+|type-I-F-CRISPR-associated-protein-Csy2
MSSLIVLHQVRVENANAIAGLTYGFPAITHFLGYSHALSRKLQSSHGLTLRGCAVICHYQQVHAYLSGWDYVFSLTRNPLTKEAKTAAFNEEGRMHMTVSLVIECDGTIANGDDGANALEKHLASLCLTQRLAGGTITNIRRVKVINYPETEVATRRLLCRLLPGFALLDRSELLAEHLNRLRQTNPQAEMLDAWLDFSALKIQAIPPQSDTPVESGAPAPWGYVGKPAAGYLVPIVTGYRAISPLYAPGEVDKTRDPHTPFRFVESLYGIGEWRGLHRITDLRQLLWGYHQEGDNYLCRCALPASVDTYLLNDEE
>NC_017160.1|WP_002211867.1|2847564_2848569_+|type-I-F-CRISPR-associated-protein-Csy3
MAKATIKTASVLAFERKLSNSDAMMYAGNWGQTDNWQPIIIKEKAVRGTISNRLKNALASDPAKLDAEIQKANLQRVDVAALPFDTDTLKMSFTLRVLGNLATPSVCNDQEYQAELASVINGYISEQSFSVLAARYAENLANGRFLWRNRVGAEDIKVCITSQTKSYQFDSNEFSLRQFSQPSKELTALAQEIEQGLAGNGFAFFTVDAFVRLGNGQEVFPSQELVLDSNSKKSKVLYQIDGIAALHSQKVGNALRTIDDWYPDATELALGPIAVEPYGSVTSRGKAYRQPKQKMDFYTLLDNWVTKGTVPAVEQQHYVMATLIRGGVFGEKGE
>NC_017160.1|WP_002211866.1|2848579_2849134_+|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MDHYLDIRVLPDPEFSAQTLLEALFAKLHRALVATIPGRVGVSFPTAGKTLGSQLRLHGSRGDLLELQSAGWLKGLQDYCECSEILPVPADVKHRTIRRVQVKSSAQRLRRRSVSKGWLTEEQARLRIPDSHDKRCDLPFLRLKSRSSEQYFLLFIEQGTLQASATTGEFSAYGLSVNATIPWF
>NC_017160.1|WP_002211865.1|2849211_2850231_-|aldo/keto-reductase
MDYIKLGHCGLQVSRLCLGTMNMGSKQWKPWVFDKAESTPLIKHALDCGINFIDLADFYSAGVGEEVVGRIVKNLMSRDELVLTTKVGYPIGHGPNNQGHSRKHIMASIDASLKRLGTDYIDIYMLHYFDINTPVEETWSAMNDIIHSGKARYTGVSTMFTWQLSKILWCCERNGFAKPINMQLQLNCAYREEEREMIPQCRDQGLGISAFSPLARGLLSCDFSSVRNKTDFFTQEMYADVTSLNIAQSVERVAKNRGITPAQVAQAWVLNHPGTDCMLVGADTIEQINSAVTALRISLNAEEHFELERNYTPCDVINDYTAGQRIAREARPPSGIFAP
>NC_017160.1|WP_002211864.1|2850241_2850745_-|formaldehyde-activating-enzyme
MQMYIGEGFAGNGVNAAHINIMIGPRDGVVGQAFAASLASPSQGHYPFIVVIKPNVAAKPMTLYVNKAEIRSELHGRATWGASQAAVAKAVAEALLANLFPPEAEDDWCIITANWVNIDCDDIDEVYRNNYRACTTALHAAMAKTPKRDQLTHALTQLSNPFFTPKA
>NC_017160.1|WP_002211863.1|2850791_2852150_-|MFS-transporter
MQTLPSEKIRMDDVPLNRFHIRIAGLTFGAHFIDGYILGLIGFALIQLKPIMALTPLWEGLLGSAALIGLFLGSLILGWISDYIGRQKIFSFSFVIITLASALQFFASTPEQLFILRVIVGIGIGGDYSVGHTLLAEFSPRKHRGVLLGAFSVIWTFGYVSASFVGHYLSMVSPEAWRWLLSSAALPALLILLVRIGTPESPRWLMGKGREDDAMAIVHKYFGPNVTLIDEEPATSTRRFLSLFGRKYWRRTAFNSLFFVCLVIPYFAIYTFLPSILNVMALSQNFATDLLLNGLLVVGALVGIVLTAFCSRRSFLISSFIFLATCLLLLSILPSNQTFWLIALFAAFTLVMSAVSNLVGVFPAESFPTEVRSMGVGFATSMSRLGSAIGTSLLPLAIVNYGMPVTTTLLAFVLIIGAIVSIAWAPETKGLTLVDASQSATTPRPPSSIIPN
>NC_017160.1|WP_002216551.1|2852273_2852483_+|hypothetical-protein
MVIGDLLTETDRLFQKRTAAMDDLFSSPGPVRLILFVMAMCQPKYKAASAFYAYPSEKKVRDPPLNSYK
>NC_017160.1|WP_002211861.1|2852597_2853524_+|LysR-family-transcriptional-regulator
MRKLPSLRMLRVFEEACHTLSFSKAAEALFMTQSAASRQIKQLENFLGKSLFIRGHRGLELTQDEMTMLPIVRQSLDLLEEGVKHVQLSNPLQHLRLQVAPTFATRWLAPRLVTLLQRNSQLQIALISEIRQKYCDFDSAIRFGDIRRDLSNGHLLCYEQLCLVASPLVMQQGRFPPLTALPQLHILNGDSRLTNWQQWLDAAQITVAAGHNALEFSTQDQVISACTTGAGYAVLDILMISHELDNGLLRQVLPLTVTSTHGYWLEIPQDKGHSPRVIIFQEWLQRELKRDIAKRYSKGEAKPLPAVL

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Crispr_ID: NC_017160_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017160_4

2876594-2876863

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRT

4 spacers

The CRISPR arrays of NC_017160_4

>merge|NC_017160|4|2876594-2876863|PILER-CR,CRISPRCasFinder,CRT
GTTCACTGCCGCACAGGCAGCTTAGAAACTGATACAATCATCCTATTTGTCCTATCCAGAAGTTCACTGCCGCACAGGCAGCTTAGAAAGACAAGAACCGAATCTTTCGCCGTGCCGTAAAGTTCACTGCCGCACAGGCAGCTTAGAAACCGAAATCATCAGATGTAATTAAGATTTTTGCTGTTCACTGCCGCACAGGCAGCTTAGAAAAGACTGATGCAAGATGGCGGTATGCGTACAGAGTTCACTGCCGCACAGGCAGCTTATAGA

>NC_017160|4|3|2876594-2876803|PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA

>NC_017160|4|4|2876594-2876863|CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA	AGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATAGA

>NC_017160|4|3|2876594-2876863|CRT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA	AGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017160.1\|WP_002209743.1\|2862746_2863955_+\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|225865
NC_017160.1\|WP_002217041.1\|2863917_2864214_-\|biofilm-formation-regulator-BssS	unknown	unknown	gnl\|CDD\|183419
NC_017160.1\|WP_002213109.1\|2865277_2866324_-\|dihydroorotase	unknown	unknown	gnl\|CDD\|235474
NC_017160.1\|WP_002359655.1\|2879587_2881513_+\|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	unknown	unknown	gnl\|CDD\|226471
NC_017160.1\|WP_002223323.1\|2883895_2885443_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_017160.1\|WP_002210300.1\|2882917_2883847_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380623
NC_017160.1\|WP_002209743.1\|2867122_2868331_-\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|225865
NC_017160.1\|WP_002213107.1\|2866558_2866846_+\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|224278
NC_017160.1\|WP_002213110.1\|2864719_2864965_-\|DNA-damage-inducible-protein-I	unknown	unknown	gnl\|CDD\|182578
NC_017160.1\|WP_002214718.1\|2875684_2876233_-\|DUF1440-domain-containing-protein	unknown	unknown	gnl\|CDD\|226008
NC_017160.1\|WP_002214717.1\|2868364_2869243_-\|transglycosylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273954
NC_017160.1\|WP_002210307.1\|2891744_2892047_-\|hypothetical-protein	unknown	unknown	unknown
NC_017160.1\|WP_002210296.1\|2876866_2877721_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NC_017160.1\|WP_002211850.1\|2861270_2862386_-\|N-methyl-L-tryptophan-oxidase	unknown	unknown	gnl\|CDD\|236887
NC_017160.1\|WP_002210297.1\|2878026_2879553_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143404
NC_017160.1\|WP_002210294.1\|2869299_2875278_-\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NC_017160.1\|WP_002210306.1\|2890726_2891542_+\|5-deoxy-glucuronate-isomerase	unknown	unknown	gnl\|CDD\|226241
NC_017160.1\|WP_002210303.1\|2886507_2887641_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_017160.1\|WP_002210304.1\|2887672_2889643_+\|5-dehydro-2-deoxygluconokinase	unknown	unknown	gnl\|CDD\|378281
NC_017160.1\|WP_002214723.1\|2892111_2893902_+\|ABC-transporter-ATP-binding-protein/permease	unknown	unknown	gnl\|CDD\|227590

Protein	Function_ID	Function_description	E-value
NC_017160.1\|WP_002209743.1\|2862746_2863955_+\|IS256-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.39969e-152
NC_017160.1\|WP_002217041.1\|2863917_2864214_-\|biofilm-formation-regulator-BssS	gnl\|CDD\|183419	PRK12301, bssS, biofilm formation regulator BssS.	5.87526e-55
NC_017160.1\|WP_002213109.1\|2865277_2866324_-\|dihydroorotase	gnl\|CDD\|235474	PRK05451, PRK05451, dihydroorotase; Provisional.	0
NC_017160.1\|WP_002359655.1\|2879587_2881513_+\|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	gnl\|CDD\|226471	COG3962, COG3962, Acetolactate synthase [Amino acid transport and metabolism].	0
NC_017160.1\|WP_002223323.1\|2883895_2885443_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NC_017160.1\|WP_002210300.1\|2882917_2883847_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380623	cd19968, PBP1_ABC_IbpA-like, periplasmic sugar-binding protein IbpA of an ABC transporter and similar proteins. The periplasmic binding protein (PBP) IbpA mediates the uptake of myo-inositol by an ABC transporter that consists of the PBP IbpA, the transmembrane permease IatP, and the ABC IatA. IbpA shares homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge.	4.31227e-120
NC_017160.1\|WP_002209743.1\|2867122_2868331_-\|IS256-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.39969e-152
NC_017160.1\|WP_002213107.1\|2866558_2866846_+\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|224278	COG1359, COG1359, Uncharacterized conserved protein [Function unknown].	1.75282e-21
NC_017160.1\|WP_002213110.1\|2864719_2864965_-\|DNA-damage-inducible-protein-I	gnl\|CDD\|182578	PRK10597, PRK10597, DNA damage-inducible protein I; Provisional.	5.41941e-49
NC_017160.1\|WP_002214718.1\|2875684_2876233_-\|DUF1440-domain-containing-protein	gnl\|CDD\|226008	COG3477, COG3477, Predicted periplasmic/secreted protein [Function unknown].	2.91652e-69
NC_017160.1\|WP_002214717.1\|2868364_2869243_-\|transglycosylase-domain-containing-protein	gnl\|CDD\|273954	TIGR02073, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein 1C. This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	1.09445e-118
NC_017160.1\|WP_002210296.1\|2876866_2877721_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	1.17523e-68
NC_017160.1\|WP_002211850.1\|2861270_2862386_-\|N-methyl-L-tryptophan-oxidase	gnl\|CDD\|236887	PRK11259, solA, N-methyl-L-tryptophan oxidase.	0
NC_017160.1\|WP_002210297.1\|2878026_2879553_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl\|CDD\|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NC_017160.1\|WP_002210294.1\|2869299_2875278_-\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NC_017160.1\|WP_002210306.1\|2890726_2891542_+\|5-deoxy-glucuronate-isomerase	gnl\|CDD\|226241	COG3718, IolB, Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism].	3.14642e-169
NC_017160.1\|WP_002210303.1\|2886507_2887641_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.07432e-69
NC_017160.1\|WP_002210304.1\|2887672_2889643_+\|5-dehydro-2-deoxygluconokinase	gnl\|CDD\|378281	pfam09863, DUF2090, Uncharacterized protein conserved in bacteria (DUF2090). This domain, found in various prokaryotic carbohydrate kinases, has no known function.	0
NC_017160.1\|WP_002214723.1\|2892111_2893902_+\|ABC-transporter-ATP-binding-protein/permease	gnl\|CDD\|227590	COG5265, ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones].	0

>NC_017160.1|WP_002214718.1|2875684_2876233_-|DUF1440-domain-containing-protein
MSEKRVNLQVIAWATIIGGFVSSLVKSGTEVNMPPRVVGEISPPAANIDAWLGWLGINSHSMDYVYQGVTISGTVVLYHWLFSFVFAFVYVLLSAYWPKVRLWYSAAYGLSITVAIHGVLIPALGFRHPAYLAGETGWLWNLNGYELWSEIIGHLCWSASLEICLVAVLAFFSKPIKGIWAN
>NC_017160.1|WP_002210294.1|2869299_2875278_-|alpha-2-macroglobulin-family-protein
MDLLRFLLISPFALIKGLYRLSAYLLRLVGRLLRPVVGNLNWRAPQWMTKTANGLHCAFNRSEQWVAKHPKGISAAIVLLMAAASAAFYGYHWYLNRPQPIEPAPMVYQETSIRVSAPRTVNYQAQKPEAQPLSLNFMHSAAPITAMGQVVDQGISLTPAIEGEWKWATERTLVFTPKKAWPMGANYQITIDTEKLLAPQIKLNQTELNFTTPAFAYQLEKAEYYQDPQEAQKRSTIFHVQFNAPVDVASFEKQILLGLVEGKSKSEKKLNFSVVYDEKKLNAWIHSQPLMPMDKGGSVHLSINKGVNASVAATPTTQAQNKWVSVPNLYSLAVNSINATLVESDNNNGERALIIAISDAVKDKEIKNAVKAWLLPQHNFQAKESAKTSTDFYPWDMDDIDDNLLQQSTPLALTLNEAEQEYQPIFSFKFDAPSYRTLLIEVNNSLTSVGGYKMPEKIYQIVRVPDYPKTLRFMSQGSLLSMQGDKQISVAARNMTGMKLDIKRVIPSQLQHIVSFKSSEYSSAHFNRLSDEYFTEHFQYQTALNNDNPGEINYQGVDLSRYLANNPSARRGVFLLTLSAWDPEKRDNQQHSEEDYDEDQEWVGDSRFVVITDLGIITKQSQDRSRDVFVQSIHSGLPAADAKVSVVAKNGVVLLSQITDSKGHVHFPALDAFKNERQPVMFLVEKEGDVSFLPTRATYDRNLDFSRFDIDGEETPSDPRTLSSYLFSDRGVYRPGDRFNIGLITRTANWATALDGVPLRAEIRDPRDTLMSTLPITLDSSGFNELSYTTGENSPTGEWNVYLYLVGKNNETSMLLGHTTVNVKEFEPDRLKVQLQLTPERQQGWVKPQELQANINVQNLFGTPAQERRVTSRLILRPMYPSFAPFPDYLFYENRHNSDGFETELEEQTTDLQGMATIPLDLKSYADATYQLQLLSEAFEAGGGRSVAATARVLVSPYDSLVGVKADGDLSYINRDAVRKLNIIAVDPSLNKIALPDLSLSLIEQKYISVLTKQDSGVYKYQSRLKEQLVSEQPLQISPTGTDFTLVTQQPGDFILVVKDSQGQVLNRISYTVAGNANLTRSLDRNTELKLKLNQAEYLQGEEIEIAINAPYAGSGLITIEKDKVYSWQWFHSDTTSSVQRIRIPPAMEGNGYINVQFVRDVNSDEIFMSPLSYGVMPFKISTKARQAAIELASPSVIKPGEVLPIKVTTDSPQRVVVFAVDEGILQVARYRLKDPLDYFFRKRELSVQSAQILDLILPEFSKLMALTSAPGGDAGEGLDLHLNPFKRKQDKPVAYWSGITEVNGETTFNYPIPDYFNGKIRVMAISATPDRIGKVQTSTTVRDNFILTPNVPAMVAPGDEFDVTVGVSNNLQGLKGKAVDITVRLTPPPQLEVVGEAQHSLSLAEKRETLVSFRLRARSALGDAPLVFDASYGSQSSRRTVSTSVRPAMPFRTQSVMGRMEGNKHTVTNLRQMFDNYAQRQATASHSPLVLTQGLARYLADYPYYSSEQIVSRSIPLIMQSKHPEMDSALNQNEVRDQLKNMLRILSSRQNSTGAIGLWHASPTPDPFVTPYVVQFLLEAKSAGYSLPNDILEGANNALRLLAARPYDDLYSLRLRAFAVYLLTLQGEITTNTLASVQSTLQQLYPDSWQTDLSAIYLASSYRLLKMDDEANKLLQPTWKQLGKAYSKAWWTQNYFDPLVQDATRLYLITRHFPEKVSSIPPQALENMVLALRDEHYTTYSSAMSILALESYTSQVAAQQDTPETLQIIEISKSKGIDPNVISTLNGLFVQGDFTGEAKAIQFNNYASAPAWYVVNQSGYDLQPPKDAISNGLEISRSYTDEQGKPVTQVTLGQKVNVHLKIRANAKQGQNNLAIVDLLPGGFEVVQQTAPEPEFYDNQDDQDEETGSGWQSPLMVSGSSWYPDYSDIREDRVIIYGSASTDVKEFIYQIKSTNTGRFVVPPAYGEAMYDRNVQALSVGKGHILVVPPEAK
>NC_017160.1|WP_002214717.1|2868364_2869243_-|transglycosylase-domain-containing-protein
MRIPTLMATKRLLQNILMALFLLALLVIGFRLWPHPPLSQGLPLSTAYYDRHGTLLRLSLANDDRYRLWTPLEEISPLVIQGIQLHEDRGFYYHPGVNPISLLRGFWQSYVQGGRQQGGSTLTMQLARMHWHLNTRSPTGKLRQIARAIQLELSYSKHDILEAYLNYAPYGRNIESIAAASLIYFDKKPQQLTLPEALTLAVLPQSPSYRIDPTTGVLGSALTQARNRLFVRWQQTYPTDSSQMALFQLPLSLRQPEKMPYIAPHFIEQIRRQNQQLANTRDCKQYCVIACF
>NC_017160.1|WP_002209743.1|2867122_2868331_-|IS256-family-transposase
MDEKKLKALAAELAKGLKTEADLNAFSRMLTKLTVETALNAELTEHLGHEKNTPKSGSNTRNGYSSKTLLCDDGEIELNTPRDRENTFEPQLIKKNQTRITQMDSQILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDAVKEQVAEWQNRQLDALYPIVYMDCIVVKVRQNGSVINKAVFLALGINTEGQKELLGMWLAENEGAKFWLSVLTELKNRGLQDILIACVDGLKGFPDAINSVYPQTHIQLCIIHMVRNSLKYVSWKDYKAVTSGLKMVYQAPTEEAALMALDKFAEAWDDKYPQISKSWRTHWENLNTFFGYPPDIRKAIYTTNAIESVNSVIRAAIKKRKVFPTDDSVRKVVYLAIKDASKKWSMPIQNWRLAMSRFIIEFGDRLSDHL
>NC_017160.1|WP_002213107.1|2866558_2866846_+|antibiotic-biosynthesis-monooxygenase
MEIRVIASIVAKTEFIEEVKAALHQIIEPSREEKGNLQYDLHTESEQKGSFVFFERWASDEALEKHNKTEHFKQLVKAIDGKLESLEIKKVKQIA
>NC_017160.1|WP_002213109.1|2865277_2866324_-|dihydroorotase
MTAQPQTLKIRRPDDWHIHLRDDEMLSTVLPYTSEVFARAIVMPNLAQPITTVASAIAYRERILAAVPAGHKFTPLMTCYLTNSLDAKELTTGFEQGVFTAAKLYPANATTNSTHGVSDIPAIYPLFEQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADYVLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQALRAAVASGSDRFFLGTDSAPHAKHRKESSCGCAGVFNAPAALPAYASVFEELNALQHLEAFCALNGPRFYGLPVNDDVVELVRTPFLQPEEIPLGNESVIPFLAGQTLNWSVKR
>NC_017160.1|WP_002213110.1|2864719_2864965_-|DNA-damage-inducible-protein-I
MRVEVSIDKKNQLPAGAIEALTQELTKRLNTKFPDTATAVQVRYASANNLSVLGGAKTDKDVISEILQEIWESADDWFDAE
>NC_017160.1|WP_002217041.1|2863917_2864214_-|biofilm-formation-regulator-BssS
MDRNNEVIQTHPVVGWDISTVDVYDAMMIRLHYLSSMDQPQEDALVDRTLWLTTDVARQLINILEAGIAKIESSESLSIILCNCHRIKGDRSGGHRTR
>NC_017160.1|WP_002209743.1|2862746_2863955_+|IS256-family-transposase
MDEKKLKALAAELAKGLKTEADLNAFSRMLTKLTVETALNAELTEHLGHEKNTPKSGSNTRNGYSSKTLLCDDGEIELNTPRDRENTFEPQLIKKNQTRITQMDSQILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDAVKEQVAEWQNRQLDALYPIVYMDCIVVKVRQNGSVINKAVFLALGINTEGQKELLGMWLAENEGAKFWLSVLTELKNRGLQDILIACVDGLKGFPDAINSVYPQTHIQLCIIHMVRNSLKYVSWKDYKAVTSGLKMVYQAPTEEAALMALDKFAEAWDDKYPQISKSWRTHWENLNTFFGYPPDIRKAIYTTNAIESVNSVIRAAIKKRKVFPTDDSVRKVVYLAIKDASKKWSMPIQNWRLAMSRFIIEFGDRLSDHL
>NC_017160.1|WP_002211850.1|2861270_2862386_-|N-methyl-L-tryptophan-oxidase
MDYDLIVIGSGSVGSAAGYYASQAGLNVLMIDSAMPPHQAGSHHGETRIMRHAYGEGEKYVPLVLRAQALWDQLAAQTGEKLFQACGVINLGPDNSTFLQNVQRSAQQYDLPVETLNSTQIREKWPVFTVPDNYIAVFEPQSGYLRSELAVKTLIKAVTEAGCGILFNCPVTAIESHQAGVDVVTIDGTYSATKVVVTAGTWVKELLPTLPVTPVRKVFSWHQADGRYSEANHFPAFTVEMPDNILYYGFPAQNDALKLGKHHGGQLIESAAQRKPFGRYAEDGTEVFSFLRHFLPGVGVCLRGEACSYDMSPDEDFIIDTLPEDERVMVVSGLSGHGFKFATALGEVAALFAQDKPSPIDISAFSLARFR
>NC_017160.1|WP_002210296.1|2876866_2877721_-|MurR/RpiR-family-transcriptional-regulator
MTTASNLSELQQQIRDRYDNLSKRLQQVSRYVLDNTNSVAFDTVAVIAERADVPPSTLIRFANAFDFSGFNEMKQLFRMNLVEETASYTDRARLFRAMESEAVPETPLGILQEFARSNAQALQQLAARTEPEMLQRAVELLAQADTIYVVGLRRSFSVAAYLTYALSHLECRPVQLHGLGGMLREQVNSIKARDIVVSISFSPYAEETVMVSEIAASAGARQIVITDSQISPLATFSDLCFVVKEAQVDAFRSQSATLCLVQSLVVALAYQQEAQAGAALAHRQ
>NC_017160.1|WP_002210297.1|2878026_2879553_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
METVANFINGKCVFSCGNSVTSGSPRAQAIFNSATGEPIRQVMMSTAQETEQAITAAQQAFASWSRQAPLKRARVMFRFKSLLEQHLDALAQLISEEHGKVYSDAVGELTRGLEVVEFACGIPHLQKGEHSANVGTGVDNHSLMQPLGVCVGITPFNFPAMVPMWMFPIALATGNTFVLKPSEKDPSLAVRLAQLLTEAGLPDGVFNVVQGDKTAVDVLLTDPRVQAVSFVGSTPIAEYIYQTASAHGKRCQALGGAKNHCILMPDADMDMAASAIMGAAYGAAGERCMALSVVLAVGDETADNLCARLEQQISTLRVGPGLAQEPENDMGPLISAPHRAKVLGYIDSGVAQKATLRIDGRGLKVAGHEQGYFVGPTLFDHVTPAMTIYQEEIFGPVLSVVRIADYRSAVDLINRHEYGNGTAIFTRDGGTARRFCEEVQVGMVGVNVPIPVPVAFHSFGGWKRSIFGPLNVHGNDGVRFYTRMKTITARWPEAQHDQGAAFSMPTLG
>NC_017160.1|WP_002359655.1|2879587_2881513_+|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)
MKTVRMTMAQALVRFLNQQYVAIDGQEVAFVHGVMTIFGHGNVLGIGQALEENPGHLQVHQGCNEQGMAHMAIGFAKQYRRQRIYAVSSSIGPGAANMVTAAATATANRIPLLLLPGDIYASRQPDPVLQQIEQYHDLSISTNDCFRPVSRYWDRINRPEQLMSAMLSAMRVLTDPADTGAVTLCLPQDVQGEAWDYPASFFERRVHRIERRPPDTRRLSDALSLIARKRRPLVVCGGGVRYSGAHEAFRAFVENAQLPFTETQAGKGALPSDHPLNLGGIGVTGGLAANRLAPQADLVIGIGTRLTDFTTGSKALFSHPEVAFLLLNVAEFDALKLDATALIADARVGLEALTEGLAGYRTAWQGDIIEAKAAWCDECQRLWSRTWRPDEVPEVAGHLDDSLQEYAEVLNTTLTQTRVLGLINQHIEDDAIVVGAAGSLPGDLQRLWQVKTADTYHLEYGYSCMGYEIAAAIGAKIAMPHQPVYAMVGDGSYMMLHSELHTAVQEGLKITVLLFDNAGFGCINNLQMGHGMGSFCTESRHRNHESGQLNGPLICVDFAQNAESYGCRAWRVHDEPSLLAALAASRDHPGPVLLDIKVLPKSMTHDYASWWRTGDAQIARSPAVQQAAERTQMKVKRARQY
>NC_017160.1|WP_002210300.1|2882917_2883847_+|substrate-binding-domain-containing-protein
MKKLILAALIVFTSGVAFAENEQIVFSTPNLAMPFEVHMQRTAVKTAKALGVKLQVLDGQGSSPKQVADLENAITRGAQGFIVSPNDINAISSAVEEIQQAKLPVVTLDRSVESEKKVPHFGANNYKGGEAIANYVKSMFPNGAEIVLLTGQPGSSSNIERTKGIRDSLKTGGDKYRIVVDQTGNWMRSEGMRIIESVLPSLPKPPQVILSANDDMALGAIEALQSHGMKPGEIMVTGFDAVPEALARVREGWMAVTADQRPGYAVTTAMNQLVANIRDQKAITGADFLPTMITKENLDQAERVSEAGK
>NC_017160.1|WP_002223323.1|2883895_2885443_+|sugar-ABC-transporter-ATP-binding-protein
MSQPLLKITDMAKSFSGVWALSNVQLTLEQGEIHALLGENGAGKSTLLKALSGAQPQTHGEIWFNGEMLALDDSPVERQNKGIITIYQEVNLLPNMTVAENMFLGREPRRRQVFVDEKAVNQEAQAILDYLQLNVSPTTAVARLSIAQQQMVEIARALTLNAKLIVMDEPSAALSDSEVESLHRVVRELKGRGVSIIYVTHRLHEVFQLCDRFTVFQDGRYTGSDEVAGTNVEKIIRLMVGRDVVFNRRPASETHHQDQPIRLSVQGLCREKPPLDPHGVALKDISFHVHAGEVLGIAGLVGAGRTEVARCLFGAGAFTSGNFEIDGVPYQPRDPMFALEQGIALVPEDRKKEGAVQGLSIRDNLTLSSLAGLLQWRFFVNTRKEDQLIETYRLALQIKMVNSEQAVRKLSGGNQQKVILARCMALNPRILIVDEPTRGIDVGTKSEVHQVLFDMAKQGVAVIVISSDLPEVLAVSDRIITLSEGRVTGEIHGDDASEERLMTMMTINHNALNAA
>NC_017160.1|WP_002210303.1|2886507_2887641_+|Gfo/Idh/MocA-family-oxidoreductase
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLHATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMVRFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV
>NC_017160.1|WP_002210304.1|2887672_2889643_+|5-dehydro-2-deoxygluconokinase
MSVEKQFSVSAEKTCNTENKCNTEKKFDVICMGRIAVDLYGQQIGARLEDVASFAKYLGGSSGNVAYGSARQGLRSSMLARVGDEHMGRFLREELHQVGCDTSHLTTDKKRLTALVLLSIKDRDTFPLIFYRDNCADMAITAQDFSEQYIASARSLAITGTHLSHPNTREAVLTALRYARRNGVRTVLDIDYRPVLWGLTSLGDGETRFIESHQVTAELLAVFNLFDVIVGTEEEFHIAGGSTNTLDALRGVREVSDAALVCKRGALGCSVYTEAIPQTLDEGLTVSGVRVKVLNVLGAGDAFMSGLLRGYLNDEGWPQACRYANACGALVVSRHGCAPAMPSKIELDNYLARADAVVRPDLDVHLNHLHRVTTRRRQWPELCVMAFDHRSQLEEMALQCGADLCHISTLKTLILQASREAVHTAGLQGKAGLLCDGTFGQDALNAITGAGWWIGRPIELPGSRPLAMEHGNIGSQLIGWPQEHIVKCLVFFHPEDAYSLRLEQEQKIIEVYRACCQSGHELLLEVILPAGMPRSDELYLRAISRFYNLGVYPDWWKLPPLASEGWAALNKLIERRDPHCRGVVILGLDASLEALRTGFNAAAGYPIVKGFAVGRTLFGDASLAWLKRDIDDTQLIARIRDNYLQLITLWRERGQK
>NC_017160.1|WP_002210306.1|2890726_2891542_+|5-deoxy-glucuronate-isomerase
MSRLLSRRQAPDERGLTQRITPAQAGWGYVGFEVYELNEGQPLTLTAVPDERCLVLIAGRASISTPSAQFPNIGDRMSPFERHKPWAVYVTPGEAVQVQAITPLELAVCSAPGKGTYPTRLISPEDIGAEARGKGHNQRYVHNILPEDHPADSLLVVEVYTNEGASSSYPSHKHDTDNPPHETYLEETYYHRLNPEQGFCMQRVYTDDRSLDECMAVYNREVVMVPRGYHPVATMAGYDSYYLNVMAGPVRKWIFSWENDHVWINHNYPIT
>NC_017160.1|WP_002210307.1|2891744_2892047_-|hypothetical-protein
MQSPSNNSRAHCSKPFLYRQNQWHFNQAISEYRLPAPLSAQDLTDSVNHINMSVIKDNAIRASGTAKIMMNHRLRRTAATIKPTHIAATTGQYIIEKTMI
>NC_017160.1|WP_002214723.1|2892111_2893902_+|ABC-transporter-ATP-binding-protein/permease
MDRSRILKFLLPYLWPKDNPKLRYYLIIALFFMVIAKISTTLVPLAYKSMVDTLSSENAKMLAIPISLIIAYGVARVSASLFEELRNVMFVHVSQNATRLLGLRVFRQLHALSLRFHLERQTGGLSLSIERGTQAVSTVLSRLLFSILPILFEITLVSVIMWRLLSGWFALAILVTVSCYILFTVMAVGWRTRFRRELNKANADANTKSIDSLLNYETVKYFGNEDFEAERFNLSRQLYEYAAIKNQISFTVLSFGQTAIISVGLIVMMAMAAQGIVQGQMTIGDFVLVNAYLLQLYQPLNFFGFIYSEIRQALIDMENMLDLLMVKQEITDRPDALPLQLTKGEVRFDAVSFSYDPRRPILNNVSFTIPPGKTVAIVGASGAGKSTLARLLFRFYDVTAGAVYLDDQDIRGVTQSSLREAIGIVPQDTVLFNDTLRYNIGYGKTDSTDEEIERAAKLAHIHEFIISLPDGYETRVGERGLKLSGGEKQRVAIARTILKKPSILVFDEATSALDTHTEREIQSHLREVSRDHTTLVIAHRLSTIIDADEIIVLEAGSIVERGRHDELLLKNGRYAGMWQNQYHEEEAYHEAEQPVL

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Crispr_ID: NC_017160_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_017160_5

4390211-4390322

Orphan

Consensus_repeat	Method
AAAGCACATTTGAGCAGCGAGTGAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_017160_5

>merge|NC_017160|5|4390211-4390322|CRISPRCasFinder
AAAGCACATTTGAGCAGCGAGTGAAGCCAGACCATCATCCTTAGGCTTTTAATACGTTTTTGATTTTGAATGGGTTGTTGACGTCCAAAGCACATTTGAGCAGCCGAGTGAA

>NC_017160|5|5|4390211-4390322|CRISPRCasFinder
AAAGCACATTTGAGCAGCGAGTGAAG	CCAGACCATCATCCTTAGGCTTTTAATACGTTTTTGATTTTGAATGGGTTGTTGACGTCC
AAAGCACATTTGAGCAGCCGAGTGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_017160.1\|WP_002209491.1\|4387154_4389791_+\|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl\|CDD\|234570
NC_017160.1\|WP_002223919.1\|4385617_4386781_+\|acetylornithine-deacetylase	unknown	unknown	gnl\|CDD\|235346
NC_017160.1\|WP_100067904.1\|4390532_4391887_+\|IS3-like-element-IS1661-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_017160.1\|WP_002209497.1\|4395898_4398346_-\|glycogen-phosphorylase	unknown	unknown	gnl\|CDD\|184948
NC_017160.1\|WP_002209495.1\|4392675_4393140_-\|DUF943-family-protein	unknown	unknown	gnl\|CDD\|368741
NC_017160.1\|WP_079993164.1\|4393123_4393300_-\|DUF3289-family-protein	unknown	unknown	gnl\|CDD\|132079
NC_017160.1\|WP_002209481.1\|4373704_4374508_-\|energy-transducer-TonB	unknown	unknown	gnl\|CDD\|223880
NC_017160.1\|WP_002209502.1\|4406132_4407830_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NC_017160.1\|WP_002209485.1\|4378789_4381282_-\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	unknown	unknown	gnl\|CDD\|273807
NC_017160.1\|WP_002209494.1\|4392241_4392511_-\|hypothetical-protein	unknown	unknown	unknown
NC_017160.1\|WP_002209498.1\|4398514_4399945_-\|glycogen-synthase-GlgA	unknown	unknown	gnl\|CDD\|234809
NC_017160.1\|WP_002209489.1\|4384362_4385367_-\|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl\|CDD\|234761
NC_017160.1\|WP_002226019.1\|4394221_4395736_+\|glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|237027
NC_017160.1\|WP_002228169.1\|4408037_4417079_-\|invasin-like-inverse-autotransporter-protein	unknown	unknown	gnl\|CDD\|378762
NC_017160.1\|WP_002209484.1\|4377950_4378568_-\|heme-acquisition-protein-HasA	unknown	unknown	gnl\|CDD\|368907
NC_017160.1\|WP_002215335.1\|4383420_4384197_-\|acetylglutamate-kinase	unknown	unknown	gnl\|CDD\|239782
NC_017160.1\|WP_002209487.1\|4381880_4383254_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179883
NC_017160.1\|WP_002209482.1\|4374572_4375901_-\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|130902
NC_017160.1\|WP_002209499.1\|4401452_4403441_-\|glycogen-debranching-protein-GlgX	unknown	unknown	gnl\|CDD\|235152
NC_017160.1\|WP_002209483.1\|4375976_4377785_-\|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl\|CDD\|226969

Protein	Function_ID	Function_description	E-value
NC_017160.1\|WP_002209491.1\|4387154_4389791_+\|phosphoenolpyruvate-carboxylase	gnl\|CDD\|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NC_017160.1\|WP_002223919.1\|4385617_4386781_+\|acetylornithine-deacetylase	gnl\|CDD\|235346	PRK05111, PRK05111, acetylornithine deacetylase; Provisional.	0
NC_017160.1\|WP_100067904.1\|4390532_4391887_+\|IS3-like-element-IS1661-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	9.01643e-48
NC_017160.1\|WP_002209497.1\|4395898_4398346_-\|glycogen-phosphorylase	gnl\|CDD\|184948	PRK14986, PRK14986, glycogen phosphorylase; Provisional.	0
NC_017160.1\|WP_002209495.1\|4392675_4393140_-\|DUF943-family-protein	gnl\|CDD\|368741	pfam06092, DUF943, Enterobacterial putative membrane protein (DUF943). This family consists of several hypothetical putative membrane proteins from Escherichia coli, Yersinia pestis and Salmonella typhi.	1.80736e-84
NC_017160.1\|WP_079993164.1\|4393123_4393300_-\|DUF3289-family-protein	gnl\|CDD\|132079	TIGR03034, TIGR03034, conserved hypothetical protein. Members of this protein family have been found in several species of gammaproteobacteria, including Yersinia pestis and Y. pseudotuberculosis, Xylella fastidiosa, and Escherichia coli UTI89. As many as five members can be found in a single genome. The function is unknown. [Hypothetical proteins, Conserved].	5.70966e-16
NC_017160.1\|WP_002209481.1\|4373704_4374508_-\|energy-transducer-TonB	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	1.51188e-39
NC_017160.1\|WP_002209502.1\|4406132_4407830_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
NC_017160.1\|WP_002209485.1\|4378789_4381282_-\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	gnl\|CDD\|273807	TIGR01785, Heme/hemopexin_utilization_protein_C, TonB-dependent heme/hemoglobin receptor family protein. This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	8.20794e-132
NC_017160.1\|WP_002209498.1\|4398514_4399945_-\|glycogen-synthase-GlgA	gnl\|CDD\|234809	PRK00654, glgA, glycogen synthase GlgA.	0
NC_017160.1\|WP_002209489.1\|4384362_4385367_-\|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl\|CDD\|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	0
NC_017160.1\|WP_002226019.1\|4394221_4395736_+\|glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|237027	PRK12266, glpD, glycerol-3-phosphate dehydrogenase; Reviewed.	0
NC_017160.1\|WP_002228169.1\|4408037_4417079_-\|invasin-like-inverse-autotransporter-protein	gnl\|CDD\|378762	pfam11924, IAT_beta, Inverse autotransporter, beta-domain. This is a family of beta-barrel porin-like outer membrane proteins from enteropathogenic Gram-negative bacteria. Intimins and invasins are virulence factors produced by pathogenic Gram-negative bacteria. They carry C-terminal extracellular passenger domains that are involved in adhesion to host cells and N-terminal beta domains that are embedded in the outer membrane. This family represents the beta-barrel porin-like domain in the outer membrane that can be found in intimins, invasins and some inverse autotransporters.	4.45704e-147
NC_017160.1\|WP_002209484.1\|4377950_4378568_-\|heme-acquisition-protein-HasA	gnl\|CDD\|368907	pfam06438, HasA, Heme-binding protein A (HasA). Free iron is limited in vertebrate hosts, thus an alternative to siderophores has been developed by pathogenic bacteria to access host iron bound in protein complexes. HasA is a secreted hemophore that has the ability to obtain iron from hemoglobin. Once bound to HasA, the heme is shuttled to the receptor HasR, which releases the heme into the bacterium.	9.51098e-102
NC_017160.1\|WP_002215335.1\|4383420_4384197_-\|acetylglutamate-kinase	gnl\|CDD\|239782	cd04249, AAK_NAGK-NC, AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of ornithine biosynthesis. There are two variants of this pathway. In one, typified by the pathway in Escherichia coli, glutamate is acetylated by acetyl-CoA and acetylornithine is deacylated hydrolytically. In this pathway, feedback inhibition by arginine occurs at the initial acetylation of glutamate and not at the phosphorylation of NAG by NAGK. Homodimeric NAGK-NC are members of the Amino Acid Kinase Superfamily (AAK).	2.52737e-136
NC_017160.1\|WP_002209487.1\|4381880_4383254_-\|argininosuccinate-lyase	gnl\|CDD\|179883	PRK04833, PRK04833, argininosuccinate lyase; Provisional.	0
NC_017160.1\|WP_002209482.1\|4374572_4375901_-\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl\|CDD\|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	3.16318e-105
NC_017160.1\|WP_002209499.1\|4401452_4403441_-\|glycogen-debranching-protein-GlgX	gnl\|CDD\|235152	PRK03705, PRK03705, glycogen debranching protein GlgX.	0
NC_017160.1\|WP_002209483.1\|4375976_4377785_-\|type-I-secretion-system-permease/ATPase	gnl\|CDD\|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0

>NC_017160.1|WP_002209491.1|4387154_4389791_+|phosphoenolpyruvate-carboxylase
MNEQYSAMRSNVSMLGTLLGDTIKEALGEHILDRVETIRKLSKSSRAGNEASRQELLTTLQNLSNDELLPVARAFSQFLNLTNTAEQYHSISPHGEAASNPEALAQLFTRLKDKKLSDQDMRSAVDDLSIELVLTAHPTEITRRTLIHKLVEVNTCLSQLDHNDLADYERNKIMRRLRQLVAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWEGVPAFLREFNEQLENSLDYRLPVEAVPIRFTSWMGGDRDGNPNVTAEITRHVLLLSRWKATDLFLRDIQVLVSELSMSECTPELRELAGGEEVLEPYRQLMKNVRTQLTNTQAYLEARLKGERVLPPHDLLVSNDQLWEPLYACYQSLKACGMEIIANGQLLDTLRRVRCFGVPLVRIDVRQESTRHTDAIAELTRYLGLGDYESWSESDKQAFLVRELNSKRPLVPLKWEPSAETQEVLETCRVIAEAPQGSIAAYVISMAKVPSDVLAVHLLLKEAGCPFTLPVAPLFETLDDLNNADDVMTQLLGIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYRAQDALIKTCEKAGITLTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKFGLPEVTISSLALYAGAILEANLLPPPEPKKEWIEVMDLLSDASCDMYRSYVRENPEFVRYFRAATPELELGKLPLGSRPAKRRPDGGVESLRAIPWIFAWTQNRLMLPAWLGAGAGLQRAIDAGKQDVLATMCRDWPFFSTRIGMLEMVFAKADLWLAEYYDQRLVDKSLWPLGQQLRDQLAADIKVVLAIANDDHLMADLPWIAESIALRNVYTDPLNVLQAELLHRSRQQEHPDACVEQALMVTIAGVAAGMRNTG
>NC_017160.1|WP_002223919.1|4385617_4386781_+|acetylornithine-deacetylase
MKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRHKFNLLASIGENENGEGHGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKGFFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFAANTQLRPDFAIIGEPTSLQPVRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIPYPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSIDELHPPIPGYECPTDHHMVGVIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAHQPDEFIDMAFIEPTRELIGQLVDHFCQQK
>NC_017160.1|WP_002209489.1|4384362_4385367_-|N-acetyl-gamma-glutamyl-phosphate-reductase
MLNTLIVGASGYAGAELTAYLNRHPHMNITGLAVSAQSADAGKLLSDLHPQLKGILDLPLQPLVDVAQAAKGIDVVFLATAHEVSHDLAPQFLAAGCVVFDLSGAFRVRDAAFYSQYYGFEHQHPDWLDKAVYGLAEWQSEDIKQAQLIAVPGCYPTASQLALKPLVDGQLLNDAQWPVINAVSGVSGAGRKASMGNSFCEVSLQPYGLFTHRHQPEIVTHLGTPVIFTPHLGNFARGILATITCRLKAGVTAQNIADAYHHAYQNKPLVRLYQQGVPALKAVVGLPFCDIGFSVQGEHLIIVATEDNLLKGAAAQAVQCMNIRFGFPETQSLL
>NC_017160.1|WP_002215335.1|4383420_4384197_-|acetylglutamate-kinase
MMNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVVKKNGLRVTPADQIDIITGALAGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELGHVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHSEQLPALFNGVPIGTRISV
>NC_017160.1|WP_002209487.1|4381880_4383254_-|argininosuccinate-lyase
MALWGGRFSQAADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLNADEQQQLEQALSVLLEEVQANPHAILASDAEDIHSWVETKLIDKVGDLGKKLHTGRSRNDQVATDLKLWCKFQITELQTAVQQLQQALVMTAEANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLSRDESRLQDTLKRLDVSPLGCGALAGTAYAIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNSGEAAFVDLSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMTMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCKEAAEQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEALALSDLQQFSSVIGDDVYPILALQSCLDKRVAKGGVSPQQVASAIAEAKARLF
>NC_017160.1|WP_002209485.1|4378789_4381282_-|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor
MDNIIRDKKTIISVNKITTCILFALVTQGYSGQLAANTAETPTNNNDMALDKLNVEGKGNAHDSDWIYDEPRSVSEITREQLDNRPARHAADILEQTPGVYSSVSQQDPGLSINIRGIQDYGRVNMNIDGMRQNFMKSGHGQRNGSMYIDPEILSNVVIERGIFNGIGGAGAIGGIATFNTINASDFLAPEKELGGHIRAMTGDNGTRFIGSGALALGNPNGDILLAVSERNLKDYWPGNKGVLAGLRLYSPTRNVGDDLKNTKTLFTGYKMRSQLAKVGWNFEAGQRLEFSYLQTQIASPNASMLSEVLALSPSGKEITKIGWRNTSFTNVENRNIALDYRLNPEHISWLDATAKIYYVDTNDETDNANSLFKEYFWTQTRLKTRGLQLQNTNTFTPSDAHQIRLKYGLEWFSDKSEGYSTRKLIERTTPPGKRAITSTFAQLNYEYDDWLRLEGGLRYDQFRLKGNTWLHTRSFLQPYTFENPCDRRIHEQSEKPGSRCSSRRPATMRWDVDRCEQQLSPTLAMGVKPGLEWLEFFGSYGKSWRPPAMTEVLATGTAHGYSWVLPNPFVAAERARTWEAGFNIQQSNLFIEDDHFAAKVAYFDTRIANYINLELGKAKPKFGGDSFTDVAYVNNLLKTRFRGLEYQLSYDAGTFYTNINYTRMIGVNNVCSPYAWLGGLQSVKYKYVGKVEQIYAVENEVANNYVTCMNANVLFGSSAYLPGDRGSLTLGSRIFDRRLDFGTVIRYNKGYQDRSAQDENGNPLTAYVADWPKYIVYDLYASYKVTNNLILRSSIENITNRAYLVNYGDTLSFAPSRGRTIQGGFEYKF
>NC_017160.1|WP_002209484.1|4377950_4378568_-|heme-acquisition-protein-HasA
MSTTIQYNSNYADYSISSYLREWANNFGDIDQAPAETKDRGSFSGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKYSFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDSGKSMTENHQGDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPDSGYMSDAPMVDTVGVVDCHDMLLAA
>NC_017160.1|WP_002209483.1|4375976_4377785_-|type-I-secretion-system-permease/ATPase
MESCKTPGASSVPPTILSVLAGNKKILWGIGLFTAVINLLMLAPAIYMLQVYDRVLASANTMTLLMLTVLVLGVFVFIGLLEWVRSAVVIRLGTQIDMQLNQPVFNAAFAANLKGHNTPAAQALNDLTVLRQFATGNALFAFFDAPWFPLYLLVIFLLHPWLGMLAAAGAGILVVLAWLNQWICKKPLHDASIITSHATQQANANLRNADVIEAMGMLKALRERWLMQHANFLYQQNLASDKSSRVTAVAKSSRQALQSMMLGLGALLVIYNEITAGVMIAGSILIGRVLGPIDQLIAVWKQWSHARLAYQRLSQLLAQHPSSPTGMVLPAPQGKLNVTQLMACKPGTHIPVLHSINFELQPGDVLGILGPSGSGKSTLAKLLVASQPTFSGTVRLDSADLSRWDKTQLGEFIGYLPQNIQLFRGTVAENIARFGAIDTAKVVAAAQLADVHDLILHLPQGYDTPLGDDGEGLSGGQRQRIALARAMYGIPRLIVLDEPNASLDKEGEQALLASIIQLKQQGCTIVMITHKPELLSGSDYLLFLKNGQMDLFDRTQAVLQNIQGKDKPAVQPEAKILNSRSGWSNGVSYGIGPARTTSSPKP
>NC_017160.1|WP_002209482.1|4374572_4375901_-|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MLPESVCYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQLHVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLHHRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQSTSLQARVEQSTSDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSSGQALMEIVPSGQPLFVEAQLPVELIDKVAVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDLDPTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE
>NC_017160.1|WP_002209481.1|4373704_4374508_-|energy-transducer-TonB
MNRLQQSSDKLIFWLVGALLACGIHIYALWWLSTASIPAIPTSYPAAIMMELSAEPEFMQNLPQNSVVGITQNIIEPAVEQRVNQPDDIVDLPTLPEQPEGQREITRKEPIKVKRPAENRATSRKPVNKETQESDSKQSSPAAAASAMLSGTSQQVAAAVNSDSSHRQQAQVSWKSRLQGHLMGFKRYPSSARKQQQQGTAMIRFVVDKNGYVSSVQLSHSSGTSALDREALAIIKRAQPLPKPPAELLSQGQITLSLPVDFNLKRK
>NC_017160.1|WP_100067904.1|4390532_4391887_+|IS3-like-element-IS1661-family-transposase
MKHPFSTRLAAVQHYLSGKATLRETARQFSVGKSPLTRWIRAFRRQGEAGLEHHLSRTYTPEFRLCVVRYMMANRCSAADASAHFNIPNETIIQNWMKRYREGGKEALNPSKTGPTMPKDKYEHDSKPFSEMTHAELEKELEYLRAENAYPKKAESPERRKGTQGAAEKTRIVQALTAEHRLSCLLCAAKLARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTERISLKTGGMSPAEYRTQVEKQ
>NC_017160.1|WP_002209494.1|4392241_4392511_-|hypothetical-protein
MLTDRDIEKTPKITRDYYFEYQPGDGYNPSSTIIFNHTLDASPLKNYLNSLGYERQSQILVIVKCGHYQAKRHNPLSISGWIRRTIKFG
>NC_017160.1|WP_002209495.1|4392675_4393140_-|DUF943-family-protein
MKVKSKKNLWALLLTGSALLGYVFWLLLHPVEIVSVHQRNDYSDVLVRNFPLTDKSKINWWLENRDMLKDKYSIPKPASDGFYTVIFWDFGDGYKEEGKYDRRCFDDMKTSKNCIDKNKVFSVENDRDKDILFSVYDGMYRLEKNGKIVKMKRE
>NC_017160.1|WP_079993164.1|4393123_4393300_-|DUF3289-family-protein
MKRSYLDNDNIKNSTFNGFNLFRIGFVLQRFNQFSFKPFMTNMEATVEIAGSRNESKK
>NC_017160.1|WP_002226019.1|4394221_4395736_+|glycerol-3-phosphate-dehydrogenase
METKDLIVIGGGINGAGIAADAAGRGLSVLLLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKLAPHIAFPMRFRLPHQPHLRPAWMIRTGLFLYDHLGKRTSLPASKGLRFGPESVLKPELVRGFEYSDCWVDDARLVVLNAQEVVKHGGEVRTRTKVTRTWREQGLWMVEALDVNTGKTFTWRAKGLVNATGPWVKQFFDDGLKLKSPYGIRLIKGSHIVVPRVHNQPQAYILQNEDHRIVFVIPWLDDYSIIGTTDVEYHGDPKEVKIDDQEMTYLLKVYNDHFKKQLGRDDIVWTYSGVRPLCDDESDSPQAVTRDYTLDVADEAGQAPLLSVFGGKLTTYRKLAEHALEKLSAYYPNVGPAWTKTGALPGGDIGGSRDSYTVQLRHRYNWLPEGLARRYTRTYGSHSELILANATRLESLGEHFGHGLYEAELRYLVENEWVVELDDAIWRRTKLGMALSDEEKQRVAQWLADAHTEKQQALPLVS
>NC_017160.1|WP_002209497.1|4395898_4398346_-|glycogen-phosphorylase
MTSPFSYTSPVVSVDALKHSIAYKLMFIIGKDPTIATQHDWLNATLFAVRDRMVERWLRSNRAQLSQDVRQVYYLSMEFLLGRTLSNALLSMGIYDEIEQALDEMGLSLSELLKEENDPGLGNGGLGRLAACFLDSLATLALPGRGYGIRYEYGMFSQKIVNGQQMESPDNWLEYGNAWEFPRHNTRYKVRFGGRIQQEGSKIRWLETEEILACAYDQIIPGFDTDATNTLRLWSAQASNEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSATVQDILNRHWAMHHTFNNLADKIAIHLNDTHPVLSIPEMMRLLIDEHKFTWMDAWDVVQQVFSYTNHTLMSEALETWPVDMIGKILPRHLQIIFDINDHFLKLVEEQYPDDKELLSRVSVIDENNGRRIRMAWLAVIASHKVNGVSALHSELMVQSLFADFARIFPNRFCNKTNGVTPRRWLGLANRPLAAVLDDSIGQTWRTDLSQLSELEKNLDYPSFLLALQKAKLENKKRLAVYIAEKLNIVVNPAALFDVQIKRIHEYKRQLLNVLHVITRYNRIIDAPDNNWVPRVVIFAGKAASAYYNAKQIIHLINDVAKVINNDPRINNLLKVVFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEIREHVGEENIFIFGNTTEQVEALRKSGYNPRKYYDEDPELHQVLTQIATGTFSPEEPHRYTNLFDSLVNLGDHYQLLADYRSYVDTQEQVDALYRNRDEWSRKTLLNIANMGYFSSDRTIKEYADEIWHIKPIRL
>NC_017160.1|WP_002209498.1|4398514_4399945_-|glycogen-synthase-GlgA
MRVLHVCSELFPLLKTGGLADVIGALPAAQLAEGADVRIILPAFPDLRRGIPETVLVREIDTFAGRVALRYGHYRGIGIYLIDAPALYDRAGSPYHDASLYAYSDNYLRFALLGWMACELACGLDGYWRPEVVHAHDWHAGLTCAYLAARGRPARSVFTVHNLAYQGLFSADHLSELHLPAEFFQIYGLEFYGQISYLKAGLFFADHVTTVSPTYAKEITQPAFGYGMEGLLQALARQGRLTGILNGVDSDIWDPQSDTLLPTRYDAENLQAKAINKTHLQTAMGLQLAENKPIFAVVSRLTVQKGLDLVLEALPELLALGGQLVVLGSGDATLQEAFLAAAAEHSGQVGVQIGYHEAFSHRIIAGSDVILVPSRFEPCGLTQLYGLKYGTLPLVRHTGGLADTVVDCALENLADGSASGFVFNECEAQALVKAIRRAFVLWSRPKHWRHVQRHAMRLDFGWQLAAVDYLSLYRRL
>NC_017160.1|WP_002209499.1|4401452_4403441_-|glycogen-debranching-protein-GlgX
MAVLTHGSPTPSGAHFDGKGINFTLFSAHAEQVTLCLFDEQGQERQIAMPARTGDIWHGYLPGGKPGQRYGYRVSGPFEPSRGHRFNPHKLLIDPRTRALEGKVGDDPRFTGGVSQPDVRDSAAALPKCLVIHEEYDWQGDKPPAIPWGNTVIYEAHVRGLTQLHPDIPPELRGTYAALAHPALIEHLKTLGITTLELLPVQFHIDEPRLQKMGLSNYWGYNVLAPFAVDPDYASGREGISPLRELRDAVKALHNAGIEVILDVVFNHSAELDVFGPTLCQRGIDNASYYWLTPDGEYDNITGCGNALRLSHPYVTQWVIDCLNYWRDSCHVDGFRFDLGTVLGRTPAFDQHAPLFAALAADERLSACKLIAEPWDIGLGGYQLGNFPTGFSEWNDQYRDAMRGFWLRGEVPRGTFAQHFAASSRLFEQRGRLPSASINQITAHDGFTLLDLLCFNQKHNQMNGEENRDGSDNNHSNNFGCEGLVADAAIWQRRKACQRALLTTLLLSQGTPMLLAGDEQGHSQQGNNNAYCQNNILTWLDWGSADRALMTFTADLIRLRQQIPALTQDQWWQSGDSNVQWLDSQGQALSDAAWEQGCQQQLQILLSQRWLVLINATDHECEMHLPEGEWEGIPPFGVSDHAERLTTWRGSAHTICVLIKRD
>NC_017160.1|WP_002209502.1|4406132_4407830_+|sensor-histidine-kinase
MGISQTELIFSLLQQMCVYLVIAYLLSKTPLFIPLMQVTIRLPHKLVCYLTFSMFCIMGTYFGLNIDDSIANTRAIGAVLGGMLGGPSVGFLVGLTGGLHRYSMGGMTATACMLSTIAEGLLGGLLHLYLTRKNRLDLLFQPLVVAGITLVAEVLQMMIILAVARPFNEAVELVENIALPMMITNTIGAAMFMRILLDRRAIFEKYTTAFSAKALQIAARAEGLLRHGFDQQNSMRVARILYEELGVGAVAITDREKLLAFIGSGADHHQVGSAITSSHTHRAIELNQVVYADGNAVPYTCSISPTCKLGSTLVIPLRGEEHRVIGSIKLYEPKSKLFSSINRTLGEGIAHLLSAQILAGEFEQQKQLLAQSEIKLLHAQVNPHFLFNALNTLSVVIRRNPDHARNLVLSLSTFFRKNLKRSHDVVTLSDEIEHVNAYLEIEKARFADRLTVTVSLPNELMEAHLPAFSLQPVVENAIKHGISQMFSNGRVTLRGKLDDNTLVLEVEDNAGLYQPQPDGDGLGMSLVDRRIKARYGKEYGITVVSNAEVFTRIIIKLPFITVSEQ
>NC_017160.1|WP_002228169.1|4408037_4417079_-|invasin-like-inverse-autotransporter-protein
MLNYFRAILISWKWKLSHHTSRPHDVKEKGHPRKIKVVAWITLFFQFAFPLSLSFTPAIAAANTTNSAPTSVITPVNASILPPAARATEPYTLGPGDSIQSIAKKYNITVDELKKLNAYRTFSKPFASLTTGDEIEVPRKESSFFSNNPNENNKKDVDDLLARNAMGAGKLLSNDNTSDAASNMARSAVTNEINASSQQWLNQFGTARVQLNVDSDFKLDNSALDLLVPLKDSESSLLFTQLGVRNKDSRNTVNIGAGIRQYQGDWMYGANTFFDNDLTGKNRRVGVGAEVATDYLKFSANTYFGLTGWHQSRDFSSYDERPADGFDIRTEAYLPAYPQLGGKLMYEKYRGDEVALFGKDDRQKDPHAVTLGVNYTPVPLVTIGAEHREGKGNNNNTSVNVQLNYRMGQPWNDQIDQSAVAANRTLAGSRYDLVERNNNIVLDYKKQELIHLVLPDRISGSGGGAITLTAQVRAKYGFSRIEWDATPLENAGGSTSPLTQSSLSVTLPFYQHILRTSNTHTISAVAYDAQGNASNRAVTSIEVTRPETMVISHLATTIDNATANGIATNTVQATVTDGDGQPIIGQLINFAVNTQATLSTTEARTGANGTASTTLTHTVSGVSRVSVTLGSSSRSVDTTFVADESTAEITAANLTVTTNDSVANGSDTNVVRAKVTDAYTNAVANQSVIFSASNGATVIDQTVITNAEGIADSTLTNTTAGVSVVTATLGGQSQQVDTTFKPGSTAAISLVKLADRAVADGIDQNEIQVVLRDGTGNAVPNVPMSIQADNGAIVVASTPNTGVDGTINATFTNLRAGESVVSVTSPALVGMTMTMTFSADPRTAVVSTLAAIDNNAKADGTDTNVVRAWVVDANGNSVPGVSVTFDAGNGAVLAQNPVVTDRNGYAENTLTNLAIGTTTVKATTVTDPVGQTVNTHFVAGAVDTITLTVPVNGAVANGVNTNSVQAVVSDSGGNPVTGATVVFSSTNATAQVTTVIGTTGVDGIATATLTNTVAGTSNVVATIDTVNANIDTAFVAGAVATITLTAPVNGAVADGADTNQVDALVEDANGNPITGAAVVFSSANGATILSSTMNTGVNGVASTLLTHTVAGTSNVVATVDTVNANIDTTFVAGAVATITLTTPVNGAVADGANSNSVQAVVSDSDGNPVTGAAVVFSSANATAQITTVIGTTGADGIATATLTNTVAGTSNVVATIDTVNANIDTAFVAGAVATITLTAPVNGAVADGADTNQVDALVQDANGNAITGAAVVFSSANGADIIAPTMNTGVNGVASTLLTHTVAGTSNVVATIDTISANIDTAFVAGAVATITLTAPVNGAVADGADTNQVDALVEDANGNPITGAAVVFSSANGATILSSTMNTGVNGVASTFLTHTVAGTSNVVATIGSVTENIDTAFVAGAVATITLTAPVNGAVADGVNTNSVQAVVSDSDGNAVTGATVVFSSANATAQITTVIGTTGADGIATATLTNTVAGTSNVVATIDTVNANIDTTFVAGELENIVVSIINNNALANGADTNIVEAFVTDRFGNGVANQSLIFGTNGASIVGSSTVTTNLDGRVRASATHTVAGSSNTVIAISGAHQGYARVTFVADVSTAQLKLTSFLDNQLANGKAGNIAQALVTDAHDNLLANQSVSFALDNGAVIESQGDASSASGIVLMRFNNTLAGMTTVTATLDSTGQTETLETHFVAGKAASIEMTMTKDNAVANNIDTNEVQVLVTDVDGNAINGAVVNLTSNSGMNITPNSVTTGSDGTATATLTHTLAGSLPINARIDQVSKTINATFIADASTAQIIAGDMFIIVNDQVANGQAVNAVQARVTDSYGNPIKDQTVEFVLSNNGTIQYELDVTSVEGGVMVTFTNTLAGITNVTATVVSSGSSRNIDTTFIADVTTAHIAASDLMVIVDDAVADNLDKNEVHARVTDAKGNVLSGQTVIFTSGNGAAITTVNGISDGDGLTKATLTHTLAGTSVVTARVGNRVQSKDTTFIADRTTATIRASDLTITRNNALADGVATNAARVIVTDANGNPVPSMFVGYTSDNGALLTPTSGMTDSSGTFSTTFTHTTAGISKVTAAIVTMGISQTKDAVFIADRSTAHVSELIVVKNDSLANNSDRNIVQAHIKDAHGNVVTGMNVNFSATENVTLTANTVTTNSQGYAENTLRHNAPVTSAVTATVATDLVGLTEDVRFVAGAGARIELFRLNDGAVADGIQTNRVEARVYDVSDNLVPNSNVVFSADNGGQLVQNDVQTDALGSAYVTVSNINTGVTKVTVTADGVSASTTTTFIADRDTATLVTDRFLITHDNAVANGVVENRVLLHLVDANDNSVSGVEVNFSATNGASINASAITDINGFAIGVLTNTLSGPSDVTVTLVTPGGTESLTVTPQFIADINTANIATGDFVIIDDGAVANSVDANEVRARVTDNQGNAIAGYSVVFSSQNGATITTSGITGVDGWASAKLTHIKAGESGILARLSRPMATVHTLMPYFIADVSTATLQLFNFNPIPIIADGVMQFFVLGRVFDANQNPVGGQQVAFSATNEVTLTESNGSISTPEGSVLLSVTSTQAGVHPITGTLVSNNYTDTFGAAFIANKNTAQLSTLMVVDNNALADGVTRNQVRAHVVDSTGNSVADMAVTFTANRGAQLSKVTVLTDNNGDAVNTLTNSLVGVTVVTAKLGTAGTPLTVDTVFTAGPLATLTLVTTVNNAFADNSATNTVQATLKDVSGNPIVGEVVAFAASNGATITATDGGVSNANGIVLATLTNGTAGVSTVTATIETLTETTDTTFIAMKNLDVTVNGTTFNGDAGFPTTGFVGATFKVNSGGDNSLYDWSSSAPALVSVSGDGVVTFNAVFPTGTPTITISATPKGGGSPLSYSFRVNQWFINNNGATLNRADAITHCENVGYTMPTSTQVTNAATWMSGKRAVGNLWSEWGDFSAYTAPGWVPAEFFWLSNNHDASTALAIGLSTGTLTTMGDFMAITHVMCTRPI

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Identity
NC_017160_3	3.1\|2839804\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839804-2839835	32	NC_017160.1	2161971-2162002	1.0
NC_017160_3	3.2\|2839864\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839864-2839895	32	NC_017160.1	2166349-2166380	1.0
NC_017160_4	4.4\|2876804\|32\|NC_017160\|CRISPRCasFinder,CRT	2876804-2876835	32	NC_017160.1	2160784-2160815	1.0

1. spacer 3.1|2839804|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to position: 2161971-2162002, mismatch: 0, identity: 1.0

gtcaggaatttattcaacgtgttgcagactca	CRISPR spacer
gtcaggaatttattcaacgtgttgcagactca	Protospacer
********************************

2. spacer 3.2|2839864|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to position: 2166349-2166380, mismatch: 0, identity: 1.0

ctgatgggtaactttaatcccaaattcttttt	CRISPR spacer
ctgatgggtaactttaatcccaaattcttttt	Protospacer
********************************

3. spacer 4.4|2876804|32|NC_017160|CRISPRCasFinder,CRT matches to position: 2160784-2160815, mismatch: 0, identity: 1.0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_017160_4	4.4\|2876804\|32\|NC_017160\|CRISPRCasFinder,CRT	2876804-2876835	32	MT374852	Yersinia phage vB_YpM_3, complete genome	12-43	0	1.0
NC_017160_2	2.4\|1993024\|28\|NC_017160\|PILER-CR	1993024-1993051	28	MH616963	CrAssphage sp. isolate ctbg_1, complete genome	86944-86971	5	0.821
NC_017160_2	2.4\|1993024\|28\|NC_017160\|PILER-CR	1993024-1993051	28	MT774386	CrAssphage cr110_1, complete genome	42860-42887	5	0.821
NC_017160_2	2.4\|1993024\|28\|NC_017160\|PILER-CR	1993024-1993051	28	NZ_CP028934	Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence	25851-25878	6	0.786
NC_017160_2	2.2\|1993020\|32\|NC_017160\|CRISPRCasFinder,CRT	1993020-1993051	32	MH616963	CrAssphage sp. isolate ctbg_1, complete genome	86942-86973	7	0.781
NC_017160_2	2.4\|1993024\|28\|NC_017160\|PILER-CR	1993024-1993051	28	MK415408	CrAssphage GF1-2_000079F, complete genome	71106-71133	7	0.75
NC_017160_3	3.1\|2839804\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839804-2839835	32	NZ_CP054658	Lactobacillus reuteri strain AN417 plasmid pAN417A, complete sequence	26398-26429	7	0.781
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	JF974294	Aeromonas phage pIS4-A genomic sequence	21965-21996	7	0.781
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NC_021534	Vibrio phage pYD38-A genomic sequence	3299-3330	7	0.781
NC_017160_3	3.7\|2840164\|32\|NC_017160\|CRISPRCasFinder,CRT	2840164-2840195	32	CP049262	Cronobacter sakazakii strain CS-09 plasmid pCsaCS09b, complete sequence	69636-69667	7	0.781
NC_017160_2	2.2\|1993020\|32\|NC_017160\|CRISPRCasFinder,CRT	1993020-1993051	32	NZ_CP010358	Acinetobacter johnsonii XBB1 plasmid pXBB1-8, complete sequence	46720-46751	8	0.75
NC_017160_2	2.2\|1993020\|32\|NC_017160\|CRISPRCasFinder,CRT	1993020-1993051	32	NC_019694	Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence	20911-20942	8	0.75
NC_017160_3	3.2\|2839864\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839864-2839895	32	NZ_CP047125	Lactobacillus hilgardii strain FLUB plasmid unnamed4	1912-1943	8	0.75
NC_017160_3	3.3\|2839924\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839924-2839955	32	NZ_CP024873	Leptospira mayottensis 200901116 plasmid p1_L200901116, complete sequence	14979-15010	8	0.75
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP029117	Escherichia coli strain AR435 plasmid unnamed4	112580-112611	8	0.75
NC_017160_2	2.2\|1993020\|32\|NC_017160\|CRISPRCasFinder,CRT	1993020-1993051	32	MT774386	CrAssphage cr110_1, complete genome	42858-42889	9	0.719
NC_017160_2	2.2\|1993020\|32\|NC_017160\|CRISPRCasFinder,CRT	1993020-1993051	32	NZ_CP028934	Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence	25849-25880	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	MF679145	Escherichia coli plasmid pBJ114-96, complete sequence	37586-37617	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_KP453775	Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence	60831-60862	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP021340	Escherichia coli strain 95NR1 plasmid p95NR1A, complete sequence	67671-67702	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP021336	Escherichia coli strain 95JB1 plasmid p95JB1A, complete sequence	67672-67703	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP040920	Escherichia coli strain FC853_EC plasmid p853EC1, complete sequence	33435-33466	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP024832	Escherichia coli strain CREC-532 plasmid pCREC-532_2, complete sequence	33830-33861	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP024817	Escherichia coli strain CREC-629 plasmid pCREC-629_2, complete sequence	62769-62800	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP029117	Escherichia coli strain AR435 plasmid unnamed4	15616-15647	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP023961	Escherichia coli strain FDAARGOS_448 plasmid unnamed2, complete sequence	16858-16889	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	AP023222	Escherichia coli M505 plasmid pM505-b DNA, complete genome	93734-93765	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	AP023233	Escherichia coli YJ4 plasmid pYJ4-b DNA, complete genome	47570-47601	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP019075	Escherichia coli strain CRE1493 plasmid p1493-4, complete sequence	16520-16551	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP015837	Escherichia coli strain MS6198 plasmid pMS6198C, complete sequence	3287-3318	9	0.719
NC_017160_3	3.5\|2840044\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840044-2840075	32	NZ_CP011063	Escherichia coli str. Sanji plasmid pSJ_98, complete sequence	37637-37668	9	0.719
NC_017160_3	3.6\|2840104\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2840104-2840135	32	NZ_CP031943	Nostoc sphaeroides strain Kutzing En plasmid p2, complete sequence	4006-4037	9	0.719
NC_017160_4	4.3\|2876743\|33\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2876743-2876775	33	NZ_CP040366	Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence	923-955	9	0.727
NC_017160_3	3.3\|2839924\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839924-2839955	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	815356-815387	11	0.656
NC_017160_3	3.3\|2839924\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839924-2839955	32	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	820287-820318	11	0.656
NC_017160_3	3.3\|2839924\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839924-2839955	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2180994-2181025	11	0.656
NC_017160_3	3.3\|2839924\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839924-2839955	32	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2185925-2185956	11	0.656

1. spacer 4.4|2876804|32|NC_017160|CRISPRCasFinder,CRT matches to MT374852 (Yersinia phage vB_YpM_3, complete genome) position: , mismatch: 0, identity: 1.0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

2. spacer 2.4|1993024|28|NC_017160|PILER-CR matches to MH616963 (CrAssphage sp. isolate ctbg_1, complete genome) position: , mismatch: 5, identity: 0.821

aagttctttttgtcagcatctttaataa	CRISPR spacer
ataatctttttatcagcatcttttataa	Protospacer
* . *******.*********** ****

3. spacer 2.4|1993024|28|NC_017160|PILER-CR matches to MT774386 (CrAssphage cr110_1, complete genome) position: , mismatch: 5, identity: 0.821

aagttctttttgtcagcatctttaataa	CRISPR spacer
agtttctttttatcagcatcttcaatag	Protospacer
*. ********.**********.****.

4. spacer 2.4|1993024|28|NC_017160|PILER-CR matches to NZ_CP028934 (Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence) position: , mismatch: 6, identity: 0.786

aagttctttttgtcagcatctttaataa	CRISPR spacer
actttctttttgtcagcgtctgtaatgt	Protospacer
*  **************.*** ****.

5. spacer 2.2|1993020|32|NC_017160|CRISPRCasFinder,CRT matches to MH616963 (CrAssphage sp. isolate ctbg_1, complete genome) position: , mismatch: 7, identity: 0.781

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
taataatctttttatcagcatcttttataatt	Protospacer
* * . *******.*********** **** *

6. spacer 2.4|1993024|28|NC_017160|PILER-CR matches to MK415408 (CrAssphage GF1-2_000079F, complete genome) position: , mismatch: 7, identity: 0.75

aagttctttttgtcagcatctttaataa	CRISPR spacer
ataagacttttatcagcatctttaataa	Protospacer
* .   .****.****************

7. spacer 3.1|2839804|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054658 (Lactobacillus reuteri strain AN417 plasmid pAN417A, complete sequence) position: , mismatch: 7, identity: 0.781

gtcaggaatttattcaacgtgttgcagactca--	CRISPR spacer
ttcaggaatttattgaaagtgttg--gaattagt	Protospacer
 ************* ** ******  ** *.*

8. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to JF974294 (Aeromonas phage pIS4-A genomic sequence) position: , mismatch: 7, identity: 0.781

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
atcaggcataaagcaaatgccattcaggtaat	Protospacer
*** *   .**** *************.****

9. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NC_021534 (Vibrio phage pYD38-A genomic sequence) position: , mismatch: 7, identity: 0.781

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
atcaggcataaagcaaatgccattcaggtaat	Protospacer
*** *   .**** *************.****

10. spacer 3.7|2840164|32|NC_017160|CRISPRCasFinder,CRT matches to CP049262 (Cronobacter sakazakii strain CS-09 plasmid pCsaCS09b, complete sequence) position: , mismatch: 7, identity: 0.781

atcatgaaagacattgttcgccagtcccctga	CRISPR spacer
atcatgaaagagattgttcgccagcgcgacgt	Protospacer
*********** ************. *  .*

11. spacer 2.2|1993020|32|NC_017160|CRISPRCasFinder,CRT matches to NZ_CP010358 (Acinetobacter johnsonii XBB1 plasmid pXBB1-8, complete sequence) position: , mismatch: 8, identity: 0.75

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
gtgccatattttcgtcagcatcattaataaat	Protospacer
 *.   * ****.********* *********

12. spacer 2.2|1993020|32|NC_017160|CRISPRCasFinder,CRT matches to NC_019694 (Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence) position: , mismatch: 8, identity: 0.75

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
ttgatgctcttttggcagcttctttaataaat	Protospacer
**.*  ...***** **** ************

13. spacer 3.2|2839864|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP047125 (Lactobacillus hilgardii strain FLUB plasmid unnamed4) position: , mismatch: 8, identity: 0.75

ctgatgggtaactttaatcccaaattcttttt	CRISPR spacer
attttgaataactttaatcccaaaagctttta	Protospacer
 *  **..****************  *****

14. spacer 3.3|2839924|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024873 (Leptospira mayottensis 200901116 plasmid p1_L200901116, complete sequence) position: , mismatch: 8, identity: 0.75

tgttaaatcgtcgcctaaatttgtttgaccga	CRISPR spacer
tttagaatcgtcgcctcaacttgtttgagtaa	Protospacer
* * .*********** **.******** ..*

15. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029117 (Escherichia coli strain AR435 plasmid unnamed4) position: , mismatch: 8, identity: 0.75

atctgc-gccaaagaaaatgccattcagataat	CRISPR spacer
-taaacagttaaagaaactgccaatcagataat	Protospacer
 *  .* *..******* ***** *********

16. spacer 2.2|1993020|32|NC_017160|CRISPRCasFinder,CRT matches to MT774386 (CrAssphage cr110_1, complete genome) position: , mismatch: 9, identity: 0.719

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
caagtttctttttatcagcatcttcaatagca	Protospacer
. *. ********.**********.****.

17. spacer 2.2|1993020|32|NC_017160|CRISPRCasFinder,CRT matches to NZ_CP028934 (Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence) position: , mismatch: 9, identity: 0.719

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
taactttctttttgtcagcgtctgtaatgtgc	Protospacer
* *  **************.*** ****. ..

18. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to MF679145 (Escherichia coli plasmid pBJ114-96, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

19. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KP453775 (Klebsiella pneumoniae strain ST11 plasmid pKP12226, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

20. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021340 (Escherichia coli strain 95NR1 plasmid p95NR1A, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

21. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021336 (Escherichia coli strain 95JB1 plasmid p95JB1A, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

22. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040920 (Escherichia coli strain FC853_EC plasmid p853EC1, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

23. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024832 (Escherichia coli strain CREC-532 plasmid pCREC-532_2, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

24. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024817 (Escherichia coli strain CREC-629 plasmid pCREC-629_2, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

25. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029117 (Escherichia coli strain AR435 plasmid unnamed4) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

26. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023961 (Escherichia coli strain FDAARGOS_448 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

27. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to AP023222 (Escherichia coli M505 plasmid pM505-b DNA, complete genome) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

28. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to AP023233 (Escherichia coli YJ4 plasmid pYJ4-b DNA, complete genome) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

29. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019075 (Escherichia coli strain CRE1493 plasmid p1493-4, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

30. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015837 (Escherichia coli strain MS6198 plasmid pMS6198C, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

31. spacer 3.5|2840044|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011063 (Escherichia coli str. Sanji plasmid pSJ_98, complete sequence) position: , mismatch: 9, identity: 0.719

atctgcgccaaagaaaatgccattcagataat	CRISPR spacer
aaaacagttaaagaaactgccaatcagataat	Protospacer
*     *..******* ***** *********

32. spacer 3.6|2840104|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031943 (Nostoc sphaeroides strain Kutzing En plasmid p2, complete sequence) position: , mismatch: 9, identity: 0.719

aactactagaagcttgcccatcttaccttttc	CRISPR spacer
taccactaaaagcttgcccatctttctcataa	Protospacer
 **.****.*************** *.. *

33. spacer 4.3|2876743|33|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040366 (Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence) position: , mismatch: 9, identity: 0.727

ccgaaatcatcagatgtaattaagatttttgct	CRISPR spacer
aatggattatcagatgtaattaagtttttttcc	Protospacer
   ..**.**************** ***** *.

34. spacer 3.3|2839924|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.656

tgttaaatcgtcgcctaaatttgtttgaccga	CRISPR spacer
cagcggctccttgcctaaatttgtttgaccac	Protospacer
.. ... ** *.******************.

35. spacer 3.3|2839924|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 11, identity: 0.656

tgttaaatcgtcgcctaaatttgtttgaccga	CRISPR spacer
cagcggctccttgcctaaatttgtttgaccac	Protospacer
.. ... ** *.******************.

36. spacer 3.3|2839924|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 11, identity: 0.656

tgttaaatcgtcgcctaaatttgtttgaccga	CRISPR spacer
cagcggctccttgcctaaatttgtttgaccac	Protospacer
.. ... ** *.******************.

37. spacer 3.3|2839924|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 11, identity: 0.656

tgttaaatcgtcgcctaaatttgtttgaccga	CRISPR spacer
cagcggctccttgcctaaatttgtttgaccac	Protospacer
.. ... ** *.******************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

80507 : 133543

Bacillus_phage(37.5%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002208973.1\|80507_80996_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_002208972.1\|81184_82249_+	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	NA	NA	NA	NA
WP_002208971.1\|82297_83674_-	envelope stress sensor histidine kinase CpxA	W8CYF6	Bacillus_phage	1.5e-17	25.4
WP_002208970.1\|83670_84369_-	envelope stress response regulator transcription factor CpxR	Q6XM27	Feldmannia_irregularis_virus	1.8e-06	29.5
WP_002208969.1\|84542_85031_+	cell-envelope stress modulator CpxP	NA	NA	NA	NA
WP_002353252.1\|85747_86668_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	8.6e-73	54.3
WP_002208967.1\|87229_88132_+	CDF family cation-efflux transporter FieF	NA	NA	NA	NA
WP_002208966.1\|88349_89333_+	6-phosphofructokinase	NA	NA	NA	NA
WP_002208965.1\|89553_90543_+	sulfate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002218867.1\|90792_91569_-	molybdate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_014462214.1\|91656_93114_-	anion permease	NA	NA	NA	NA
WP_002208962.1\|93179_93893_-	4-carboxy-4-hydroxy-2-oxoadipate aldolase/oxaloacetate decarboxylase	NA	NA	NA	NA
WP_002208961.1\|93889_94627_-	PIG-L family deacetylase	NA	NA	NA	NA
WP_002208960.1\|94763_95999_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002208959.1\|96230_96998_-	triose-phosphate isomerase	NA	NA	NA	NA
WP_002208958.1\|97126_97741_-	DUF1454 family protein	NA	NA	NA	NA
WP_002208957.1\|97909_98344_+	DUF805 domain-containing protein	NA	NA	NA	NA
WP_002223912.1\|99584_100595_-	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_002218876.1\|100831_102355_-	glycerol kinase GlpK	NA	NA	NA	NA
WP_002208954.1\|102531_103380_-	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	3.2e-13	27.5
WP_002208953.1\|104007_104247_+	septal ring assembly protein ZapB	NA	NA	NA	NA
WP_002213759.1\|104454_104913_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002218877.1\|105297_107412_-	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	4.8e-34	26.5
WP_002208949.1\|107404_108697_-	HlyD family secretion protein	NA	NA	NA	NA
WP_002215873.1\|108909_109149_+	hypothetical protein	NA	NA	NA	NA
WP_002228141.1\|109778_110363_+	DUF4232 domain-containing protein	NA	NA	NA	NA
WP_002208945.1\|110479_110965_-	ribonuclease E activity regulator RraA	NA	NA	NA	NA
WP_002208944.1\|111106_112024_-	1,4-dihydroxy-2-naphthoate polyprenyltransferase	NA	NA	NA	NA
WP_002208943.1\|112259_113591_-	HslU--HslV peptidase ATPase subunit	A0A191ZC11	Erwinia_phage	1.2e-43	29.8
WP_002208942.1\|113661_114186_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_002208941.1\|114285_115131_-	cell division protein FtsN	NA	NA	NA	NA
WP_002216730.1\|115196_116225_-	DNA-binding transcriptional regulator CytR	NA	NA	NA	NA
WP_002208938.1\|116577_118776_-	primosomal protein N'	NA	NA	NA	NA
WP_002216737.1\|119018_119234_+	50S ribosomal protein L31	NA	NA	NA	NA
WP_002208936.1\|119776_120232_-	hypothetical protein	NA	NA	NA	NA
WP_002208935.1\|120580_120898_-	met regulon transcriptional regulator MetJ	NA	NA	NA	NA
WP_002208934.1\|122437_124873_+	bifunctional aspartate kinase/homoserine dehydrogenase II	NA	NA	NA	NA
WP_002208933.1\|125105_125990_+	methylenetetrahydrofolate reductase	NA	NA	NA	NA
WP_100067904.1\|126175_127530_-\|transposase	IS3-like element IS1661 family transposase	A0A1B1P773	Bacillus_phage	1.1e-55	44.7
WP_002208930.1\|127722_128481_-	DeoR/GlpR family transcriptional regulator	NA	NA	NA	NA
WP_002216348.1\|128515_129352_-\|protease	rhomboid family intramembrane serine protease GlpG	NA	NA	NA	NA
WP_002208928.1\|129369_129699_-	thiosulfate sulfurtransferase GlpE	NA	NA	NA	NA
WP_080067115.1\|130073_132452_-	HTH-type transcriptional regulator MalT	NA	NA	NA	NA
WP_000255944.1\|132520_133543_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0

DBSCAN-SWA_2

502568 : 570871

Escherichia_phage(20.0%)

transposase,tRNA,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002210509.1\|502568_505385_+\|tRNA	isoleucine--tRNA ligase	A0A2H4UVG0	Bodo_saltans_virus	1.0e-63	26.1
WP_002210508.1\|505384_505894_+	signal peptidase II	NA	NA	NA	NA
WP_002228112.1\|505961_506420_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_002210506.1\|506400_507354_+	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_002213775.1\|507735_508194_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210504.1\|508646_509468_+	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_002224759.1\|509940_511116_+	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	6.9e-51	34.3
WP_002210502.1\|511131_514365_+	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_002210501.1\|514592_515207_-	LysE family translocator	NA	NA	NA	NA
WP_002210499.1\|515530_516331_+	threonine/serine exporter ThrE family protein	NA	NA	NA	NA
WP_002210498.1\|516327_516783_+	threonine/serine exporter	NA	NA	NA	NA
WP_002210497.1\|516932_517415_+	type 3 dihydrofolate reductase	A0A219UQN5	Bacillus_phage	4.7e-30	42.6
WP_002213775.1\|517626_518085_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_071525509.1\|518526_518841_+	DUF3757 domain-containing protein	NA	NA	NA	NA
WP_002210493.1\|518967_519432_+	DUF3757 domain-containing protein	NA	NA	NA	NA
WP_002210492.1\|519521_520391_-	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH	NA	NA	NA	NA
WP_002210491.1\|520407_520785_-	Co2+/Mg2+ efflux protein ApaG	NA	NA	NA	NA
WP_002210490.1\|520798_521617_-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_002210489.1\|521609_522605_-	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_002210488.1\|522588_523893_-	peptidylprolyl isomerase SurA	NA	NA	NA	NA
WP_002228111.1\|523960_526303_-	LPS assembly protein LptD	NA	NA	NA	NA
WP_002210486.1\|526487_527321_+	co-chaperone DjlA	NA	NA	NA	NA
WP_002210485.1\|527618_528239_-\|tRNA	bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA	NA	NA	NA	NA
WP_002214747.1\|529461_530205_-	DUF2285 domain-containing protein	NA	NA	NA	NA
WP_002210482.1\|530534_531548_+	ImpA family type VI secretion system protein	NA	NA	NA	NA
WP_002210481.1\|531558_532119_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002210480.1\|532127_533630_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002210479.1\|533792_534311_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_002210478.1\|534384_534828_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002210477.1\|534860_536705_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002210476.1\|536697_537681_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002210475.1\|537698_540287_+	type VI secretion system ATPase TssH	A0A248SJW6	Salicola_phage	1.9e-77	28.7
WP_002210474.1\|540390_542739_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.1e-14	32.9
WP_002228110.1\|542751_543324_+	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_002228109.1\|543348_544971_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_002214739.1\|544996_546100_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_002214737.1\|546716_547082_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_002210471.1\|547074_547566_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002210469.1\|549020_550631_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_002214734.1\|550692_554133_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_002210468.1\|554154_554508_+	hypothetical protein	NA	NA	NA	NA
WP_002220588.1\|554763_557670_-	RNA polymerase-associated protein RapA	A0A1B1IUI1	uncultured_Mediterranean_phage	3.0e-23	37.6
WP_002210466.1\|558130_560500_-	DNA polymerase II	A0A0P0YM26	Yellowstone_lake_phycodnavirus	1.5e-31	25.5
WP_002210465.1\|560695_561463_+	DedA family protein	NA	NA	NA	NA
WP_002210464.1\|561531_562242_-	thiamine ABC transporter ATP-binding protein ThiQ	G3M9Y6	Bacillus_virus	1.0e-20	34.1
WP_002214276.1\|562228_563836_-	thiamine/thiamine pyrophosphate ABC transporter permease ThiP	NA	NA	NA	NA
WP_002214274.1\|563811_564804_-	thiamine ABC transporter substrate binding subunit	NA	NA	NA	NA
WP_002210461.1\|565743_567405_-	HTH-type transcriptional regulator SgrR	NA	NA	NA	NA
WP_001297096.1\|569069_569849_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|569848_570871_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0

DBSCAN-SWA_3

1139989 : 1227261

Escherichia_phage(14.29%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|1139989_1141012_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|1141011_1141791_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002213775.1\|1142951_1143410_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002228015.1\|1143607_1143775_-	ribosome modulation factor	NA	NA	NA	NA
WP_002211289.1\|1144043_1144622_-	membrane integrity-associated transporter subunit PqiC	NA	NA	NA	NA
WP_002211290.1\|1144618_1146271_-	intermembrane transport protein PqiB	NA	NA	NA	NA
WP_002211291.1\|1146257_1147544_-	membrane integrity-associated transporter subunit PqiA	NA	NA	NA	NA
WP_002211292.1\|1147672_1149586_-	ABC transporter ATP-binding protein	A0A2K9L3Z8	Tupanvirus	1.5e-47	28.9
WP_002211293.1\|1149591_1151712_-	bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL	NA	NA	NA	NA
WP_002211294.1\|1151811_1152924_+	MOSC N-terminal beta barrel domain-containing protein	NA	NA	NA	NA
WP_002211295.1\|1152949_1153501_-	cell division protein ZapC	NA	NA	NA	NA
WP_002211296.1\|1153683_1154694_-	quinone-dependent dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_002220013.1\|1155347_1157963_-	aminopeptidase N	NA	NA	NA	NA
WP_002228013.1\|1158679_1159885_+	nicotinate phosphoribosyltransferase	NA	NA	NA	NA
WP_014462286.1\|1160383_1161784_+\|tRNA	asparagine--tRNA ligase	A0A167RLM0	Powai_lake_megavirus	1.1e-79	35.2
WP_002211303.1\|1163419_1164610_+	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_002430096.1\|1164763_1164880_+	hypothetical protein	NA	NA	NA	NA
WP_002211304.1\|1165033_1165681_-	MBL fold metallo-hydrolase	A0A1X9I5D3	Streptococcus_phage	2.2e-22	32.3
WP_002211305.1\|1165741_1166290_-	YcbK family protein	A0A0K1LLY2	Rhodobacter_phage	7.8e-05	34.7
WP_002217987.1\|1166513_1168370_-	L,D-transpeptidase	NA	NA	NA	NA
WP_002213775.1\|1168653_1169112_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002211308.1\|1169327_1173785_-	chromosome partition protein MukB	NA	NA	NA	NA
WP_002211309.1\|1173781_1174510_-	chromosome partition protein MukE	NA	NA	NA	NA
WP_002211310.1\|1174490_1175813_-	chromosome partition protein MukF	NA	NA	NA	NA
WP_002211311.1\|1175809_1176595_-\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA
WP_002211313.1\|1177367_1178261_-	YcbJ family phosphotransferase	NA	NA	NA	NA
WP_002211314.1\|1178623_1179376_-	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_002211315.1\|1179372_1179555_-	hypothetical protein	NA	NA	NA	NA
WP_002211317.1\|1180102_1180312_-	cold-shock protein	A0A1W6JNX5	Morganella_phage	3.0e-10	50.0
WP_002226050.1\|1181030_1182458_+	VOC family protein	NA	NA	NA	NA
WP_002211319.1\|1182465_1183452_-	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_002211320.1\|1183448_1185197_-	lipid A ABC transporter ATP-binding protein/permease MsbA	W8CYL7	Bacillus_phage	8.7e-66	31.5
WP_002211321.1\|1185232_1187524_-	ComEC family protein	NA	NA	NA	NA
WP_002211322.1\|1188070_1188355_-	integration host factor subunit beta	A7KV42	Bacillus_phage	2.4e-10	40.2
WP_002211323.1\|1188415_1190089_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_002211324.1\|1190262_1190955_-	(d)CMP kinase	NA	NA	NA	NA
WP_002211325.1\|1191267_1192554_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_002211326.1\|1192716_1193802_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	4.4e-84	46.1
WP_002211327.1\|1194168_1196016_-	YadA-like family protein	NA	NA	NA	NA
WP_002211328.1\|1196036_1197131_-	YadA-like family protein	B0FIT1	Escherichia_phage	3.7e-06	32.7
WP_002211329.1\|1197399_1198437_-	L-asparaginase 2	NA	NA	NA	NA
WP_002211330.1\|1198585_1200352_+	30S ribosomal protein S12 methylthiotransferase accessory protein YcaO	NA	NA	NA	NA
WP_002211331.1\|1201048_1201906_+	formate transporter FocA	NA	NA	NA	NA
WP_002211332.1\|1201961_1204244_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.6e-157	41.2
WP_002211333.1\|1204361_1205036_-	glycosyltransferase family 25 protein	A0A2H4UUT1	Bodo_saltans_virus	7.8e-31	40.5
WP_002211334.1\|1206022_1206757_+	pyruvate formate lyase 1-activating protein	A0A2P0VNQ0	Tetraselmis_virus	3.6e-21	27.4
WP_002211335.1\|1206910_1208059_-	MFS transporter	NA	NA	NA	NA
WP_002211336.1\|1208297_1209590_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	4.0e-92	43.5
WP_002228009.1\|1209831_1211175_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	5.4e-76	39.4
WP_002211338.1\|1211185_1211794_-	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_002211340.1\|1216027_1216522_-	leucine-responsive transcriptional regulator Lrp	NA	NA	NA	NA
WP_002211341.1\|1217288_1218251_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	4.9e-63	45.7
WP_002217690.1\|1218709_1220476_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	W8CYL7	Bacillus_phage	6.8e-26	24.9
WP_002211344.1\|1220478_1222203_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	3.3e-17	31.8
WP_002211346.1\|1222421_1223132_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_002211347.1\|1223297_1223516_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_002213759.1\|1223887_1224346_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002211348.1\|1224638_1226915_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	7.4e-166	41.7
WP_002211349.1\|1226940_1227261_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	8.2e-15	42.7

DBSCAN-SWA_4

1339672 : 1358454

Shigella_phage(33.33%)

transposase,plate,coat,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213775.1\|1339672_1340131_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002208836.1\|1341512_1341740_+	YejL family protein	NA	NA	NA	NA
WP_002208837.1\|1341767_1343564_+	DUF3413 domain-containing protein	NA	NA	NA	NA
WP_002230704.1\|1343794_1344178_+	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	7.8e-36	66.7
WP_002208839.1\|1344534_1345683_+	HNH endonuclease	NA	NA	NA	NA
WP_002208840.1\|1345695_1346184_+	hypothetical protein	NA	NA	NA	NA
WP_002208841.1\|1346883_1347246_+	hypothetical protein	NA	NA	NA	NA
WP_002208842.1\|1347371_1348808_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_002208843.1\|1349098_1349839_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_002208845.1\|1350136_1350916_-\|tail	tail fiber protein	Q9MCR6	Enterobacteria_phage	7.1e-52	52.4
WP_002208846.1\|1351012_1351360_-	DUF2313 domain-containing protein	A0A2P9JZK7	Alteromonadaceae_phage	6.4e-21	41.3
WP_002215458.1\|1351356_1351617_-	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_002208847.1\|1351613_1352750_-\|plate	baseplate J/gp47 family protein	B5TK75	Pseudomonas_phage	4.5e-31	30.5
WP_002208848.1\|1352753_1353209_-	phage GP46 family protein	A0A0C4UR04	Shigella_phage	4.3e-17	43.8
WP_002215460.1\|1353205_1353802_-\|plate	phage baseplate assembly protein	NA	NA	NA	NA
WP_002208852.1\|1354867_1356274_-	DNA circularization protein	Q8SBG8	Shigella_phage	2.1e-17	33.7
WP_002208853.1\|1356540_1358034_-\|coat	coat protein	NA	NA	NA	NA
WP_002208854.1\|1358154_1358454_-\|tail	phage tail assembly protein	NA	NA	NA	NA

DBSCAN-SWA_5

1376414 : 1450222

Enterobacteria_phage(17.65%)

transposase,holin,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213759.1\|1376414_1376873_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002210826.1\|1377074_1378190_-	porin OmpC	Q1MVN1	Enterobacteria_phage	9.6e-111	57.6
WP_002210825.1\|1379293_1380448_+	MFS transporter	NA	NA	NA	NA
WP_002216093.1\|1380471_1382424_+	phosphotransferase RcsD	NA	NA	NA	NA
WP_002210824.1\|1383165_1383819_+	transcriptional regulator RcsB	NA	NA	NA	NA
WP_002228028.1\|1383886_1386760_-	two-component system sensor histidine kinase RcsC	A0A1V0SGX0	Hokovirus	3.8e-42	28.3
WP_002210821.1\|1386947_1389623_-	DNA topoisomerase (ATP-hydrolyzing) subunit A	G3M9Z5	Bacillus_virus	4.0e-102	34.4
WP_002210820.1\|1389884_1390613_+	bifunctional 3-demethylubiquinone 3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol methylase	NA	NA	NA	NA
WP_002210818.1\|1391106_1393395_+	ribonucleoside-diphosphate reductase subunit alpha	I3UMG3	Colwellia_phage	1.1e-286	64.9
WP_002210817.1\|1393557_1394688_+	ribonucleotide-diphosphate reductase subunit beta	G9IAA3	Pseudomonas_phage	7.6e-172	78.6
WP_002210816.1\|1394691_1394949_+	2Fe-2S ferredoxin-like protein	G9IAA2	Pseudomonas_phage	4.0e-20	54.9
WP_014462304.1\|1394983_1395493_+\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_002210814.1\|1395550_1396744_-	nicotinamide mononucleotide deamidase-related protein YfaY	NA	NA	NA	NA
WP_002221775.1\|1397362_1398571_+	tyrosine transporter TyrP	NA	NA	NA	NA
WP_002210812.1\|1398827_1399370_-	YfaZ family protein	NA	NA	NA	NA
WP_002210811.1\|1399730_1401170_+	catalase	A0A2K9L0T1	Tupanvirus	4.9e-99	38.8
WP_002210810.1\|1401237_1403418_-	ATP-dependent DNA helicase DinG	A0A127AW80	Bacillus_phage	1.1e-44	26.3
WP_002210809.1\|1403687_1404803_+	porin OmpF2	Q1MVN1	Enterobacteria_phage	2.1e-110	54.5
WP_002210807.1\|1405214_1406105_+	drug/metabolite exporter YedA	NA	NA	NA	NA
WP_002210806.1\|1406229_1406433_+	hypothetical protein	NA	NA	NA	NA
WP_002210805.1\|1406550_1408857_-	arginine decarboxylase	NA	NA	NA	NA
WP_002210804.1\|1408926_1410261_-	arginine/agmatine antiporter	NA	NA	NA	NA
WP_002353933.1\|1410738_1411437_-	ABC transporter permease	NA	NA	NA	NA
WP_002210802.1\|1411571_1412510_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.4e-23	33.5
WP_002210801.1\|1412506_1413661_-	ABC transporter permease	NA	NA	NA	NA
WP_002210799.1\|1415589_1416444_+	3-mercaptopyruvate sulfurtransferase	NA	NA	NA	NA
WP_002210798.1\|1416647_1418063_-	aspartate aminotransferase family protein	NA	NA	NA	NA
WP_002210797.1\|1418086_1418944_-	2OG-Fe(II) oxygenase	NA	NA	NA	NA
WP_002223523.1\|1419058_1419757_-	urea ABC transporter ATP-binding subunit UrtE	A0A2H4PQG7	Staphylococcus_phage	6.4e-12	25.6
WP_002210795.1\|1419850_1420687_-	urea ABC transporter ATP-binding protein UrtD	A0A285PWH2	Cedratvirus	4.2e-10	28.2
WP_002210794.1\|1420683_1421760_-	urea ABC transporter permease subunit UrtC	NA	NA	NA	NA
WP_002210793.1\|1421759_1423361_-	urea ABC transporter permease subunit UrtB	NA	NA	NA	NA
WP_002210792.1\|1423484_1424753_-	urea ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002210791.1\|1425180_1425654_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.7e-37	50.7
WP_002210790.1\|1425899_1426781_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_002210789.1\|1426783_1427644_-	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_002210788.1\|1427746_1428676_-	phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002210787.1\|1428712_1429549_-	phosphonate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.1e-17	30.1
WP_002210786.1\|1429756_1430005_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_002210785.1\|1430189_1431293_-	suppressor of fused domain protein	NA	NA	NA	NA
WP_002214185.1\|1431605_1431947_+	HNH nuclease family protein	NA	NA	NA	NA
WP_002210782.1\|1431972_1432512_-	class IV adenylate cyclase	NA	NA	NA	NA
WP_002210781.1\|1432721_1434434_+	D-lactate dehydrogenase	NA	NA	NA	NA
WP_002210780.1\|1434554_1435490_-	D-alanyl-D-alanine endopeptidase	NA	NA	NA	NA
WP_002210778.1\|1435828_1436008_+	hypothetical protein	NA	NA	NA	NA
WP_002228612.1\|1436081_1437020_-\|tRNA	tRNA dihydrouridine(16) synthase DusC	NA	NA	NA	NA
WP_002210776.1\|1437319_1438249_-	DUF4097 domain-containing protein	NA	NA	NA	NA
WP_002213775.1\|1438663_1439122_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002214195.1\|1440050_1440914_-	xanthosine phosphorylase	Q5YBA4	Grouper_iridovirus	2.3e-51	40.7
WP_002214197.1\|1441259_1442108_+	DMT family transporter	NA	NA	NA	NA
WP_002214199.1\|1442145_1443039_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002228035.1\|1443270_1445319_-\|holin	choline transporter	A0A2I7QNT1	Vibrio_phage	1.4e-19	28.5
WP_002218278.1\|1445682_1446279_+	transcriptional regulator BetI	NA	NA	NA	NA
WP_002218281.1\|1446336_1447809_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_002220180.1\|1447831_1449535_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	9.4e-57	31.5
WP_002213775.1\|1449763_1450222_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

1472941 : 1527973

Escherichia_phage(38.46%)

transposase,integrase,protease

attL 1480418:1480477|attR 1526086:1528040

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002210751.1\|1472941_1473760_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_002210749.1\|1475147_1476200_+	galactose-1-phosphate uridylyltransferase	NA	NA	NA	NA
WP_002210748.1\|1476196_1477348_+	galactokinase	NA	NA	NA	NA
WP_002216814.1\|1477341_1477494_+	hypothetical protein	NA	NA	NA	NA
WP_002216812.1\|1477514_1478411_+	galactose-1-epimerase	NA	NA	NA	NA
WP_002210747.1\|1478703_1479039_+	phosphate starvation-inducible protein PsiF	NA	NA	NA	NA
WP_002210746.1\|1479385_1480138_+	2,3-diphosphoglycerate-dependent phosphoglycerate mutase	NA	NA	NA	NA
WP_002210745.1\|1480319_1480445_-	hypothetical protein	NA	NA	NA	NA
1480418:1480477	attL	NA	NA	NA	NA
WP_000255944.1\|1480503_1481526_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|1481525_1482305_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210744.1\|1482314_1483331_-	3-deoxy-7-phosphoheptulonate synthase AroG	A0A0B6VT43	Edwardsiella_phage	2.8e-72	46.8
WP_002210743.1\|1483779_1484718_+	CDF family zinc transporter ZitB	A0A1V0SED0	Indivirus	1.2e-10	42.0
WP_002210741.1\|1485668_1486730_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_002210740.1\|1487459_1488269_-	cell division protein CpoB	NA	NA	NA	NA
WP_002210739.1\|1488278_1488785_-	peptidoglycan-associated lipoprotein Pal	NA	NA	NA	NA
WP_002210738.1\|1488835_1490128_-	Tol-Pal system protein TolB	NA	NA	NA	NA
WP_002210736.1\|1491527_1491956_-	colicin uptake protein TolR	NA	NA	NA	NA
WP_002210735.1\|1491968_1492655_-	Tol-Pal system protein TolQ	NA	NA	NA	NA
WP_002210734.1\|1492654_1493056_-	tol-pal system-associated acyl-CoA thioesterase	NA	NA	NA	NA
WP_002210732.1\|1493465_1493600_-	cytochrome bd-I oxidase subunit CydX	NA	NA	NA	NA
WP_002210731.1\|1493612_1494752_-	cytochrome d ubiquinol oxidase subunit II	NA	NA	NA	NA
WP_002210730.1\|1494766_1496335_-	cytochrome ubiquinol oxidase subunit I	NA	NA	NA	NA
WP_002210729.1\|1497101_1497974_-	succinate--CoA ligase subunit alpha	A0A2K9L1S3	Tupanvirus	3.6e-20	34.7
WP_002210728.1\|1497973_1499140_-	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_002210727.1\|1499252_1500476_-	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
WP_002210726.1\|1500505_1503313_-	2-oxoglutarate dehydrogenase E1 component	NA	NA	NA	NA
WP_002210725.1\|1503668_1504385_-	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_002210723.1\|1506202_1506550_-	succinate dehydrogenase membrane anchor subunit	NA	NA	NA	NA
WP_002210722.1\|1506543_1506933_-	succinate dehydrogenase cytochrome b556 subunit	NA	NA	NA	NA
WP_002210720.1\|1509031_1509610_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_002210718.1\|1510700_1512362_+	DNA repair protein RecN	NA	NA	NA	NA
WP_002210717.1\|1512475_1512817_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_002210716.1\|1512966_1513251_-	RnfH family protein	NA	NA	NA	NA
WP_011055694.1\|1513243_1513780_-	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
WP_002210714.1\|1513838_1514321_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	3.4e-28	46.2
WP_002213759.1\|1514955_1515414_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002210713.1\|1515637_1516837_+\|integrase	tyrosine-type recombinase/integrase	A0A1B5FPC6	Escherichia_phage	2.2e-108	50.2
WP_002210712.1\|1516915_1518004_+	DUF4297 domain-containing protein	NA	NA	NA	NA
WP_002215945.1\|1518054_1519725_+	hypothetical protein	NA	NA	NA	NA
WP_002215946.1\|1519886_1520114_-	hypothetical protein	NA	NA	NA	NA
WP_002210710.1\|1520921_1521809_+\|integrase	integrase domain-containing protein	NA	NA	NA	NA
WP_002210709.1\|1521801_1522002_+	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	1.6e-08	51.7
WP_002215949.1\|1522001_1522544_+	ash family protein	NA	NA	NA	NA
WP_002215950.1\|1522536_1523496_+	toprim domain-containing protein	A0A1W6JPG0	Morganella_phage	1.6e-50	41.0
WP_002210707.1\|1523492_1524581_+	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.4e-114	60.4
WP_002210705.1\|1524929_1525244_-	putative addiction module antidote protein	NA	NA	NA	NA
WP_002215951.1\|1525249_1525567_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	2.0e-13	48.1
WP_000255944.1\|1526171_1527194_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|1527193_1527973_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
1526086:1528040	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1613269 : 1683691

Escherichia_phage(33.33%)

transposase,plate,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|1613269_1614292_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002211286.1\|1614925_1615114_+	hypothetical protein	NA	NA	NA	NA
WP_002220006.1\|1615379_1615898_-	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_002224683.1\|1615966_1617718_-\|protease	Lon protease family protein	NA	NA	NA	NA
WP_002226586.1\|1617928_1618384_+	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_002213775.1\|1618552_1619011_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002213066.1\|1619200_1620262_-	porin OmpA	NA	NA	NA	NA
WP_002213065.1\|1620619_1621126_-	cell division inhibitor SulA	NA	NA	NA	NA
WP_002213064.1\|1621354_1621990_+	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_002213063.1\|1622091_1624230_-	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_002213062.1\|1624259_1624706_-	YccF domain-containing protein	NA	NA	NA	NA
WP_002221095.1\|1624899_1626954_+	DNA helicase IV	A7KV33	Bacillus_phage	1.5e-16	25.8
WP_002213060.1\|1627014_1627479_-	methylglyoxal synthase	NA	NA	NA	NA
WP_002213058.1\|1627657_1628338_-	DUF2057 family protein	NA	NA	NA	NA
WP_002213056.1\|1628653_1629070_+	CoA-binding protein	NA	NA	NA	NA
WP_002213054.1\|1629178_1629496_-	heat shock protein HspQ	NA	NA	NA	NA
WP_002213052.1\|1629556_1630747_-	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	W6LLI2	Streptococcus_phage	2.1e-26	28.1
WP_002213049.1\|1630840_1631119_+	acylphosphatase	NA	NA	NA	NA
WP_002213046.1\|1631170_1631500_-	sulfurtransferase TusE	NA	NA	NA	NA
WP_002213039.1\|1635145_1637563_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002213038.1\|1637716_1638463_-	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	3.3e-14	31.4
WP_002213036.1\|1639193_1639412_+	hypothetical protein	NA	NA	NA	NA
WP_002213034.1\|1639675_1640200_+	beta-hydroxyacyl-ACP dehydratase	NA	NA	NA	NA
WP_002213032.1\|1640189_1641473_+	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	NA	NA	NA	NA
WP_002213030.1\|1641474_1642212_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002213028.1\|1642227_1643466_+	hydroxymethylglutaryl-CoA synthase family protein	NA	NA	NA	NA
WP_014462326.1\|1643458_1644178_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_002213025.1\|1644179_1644932_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_002213024.1\|1644934_1645723_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_002228570.1\|1645809_1646250_+	lipocalin-like domain-containing protein	NA	NA	NA	NA
WP_002213017.1\|1646287_1646536_+	acyl carrier protein	NA	NA	NA	NA
WP_002213016.1\|1646634_1647483_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_002213014.1\|1648471_1648972_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002214707.1\|1649014_1650565_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002213011.1\|1650576_1651929_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002228049.1\|1652610_1654347_+	OmpA family protein	NA	NA	NA	NA
WP_002210014.1\|1654350_1654842_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002211928.1\|1657906_1660255_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	4.5e-17	32.1
WP_013060315.1\|1660270_1662568_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_002210008.1\|1662554_1663322_+	hypothetical protein	NA	NA	NA	NA
WP_086016632.1\|1663417_1664114_+\|transposase	IS1 family transposase	A0A0U2RK18	Escherichia_phage	1.3e-60	48.5
WP_002210010.1\|1664722_1665358_+	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_013060322.1\|1665373_1667674_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_002211930.1\|1667670_1668444_+	hypothetical protein	NA	NA	NA	NA
WP_002211931.1\|1668597_1668858_+	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_002211932.1\|1668873_1671057_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_002214564.1\|1671229_1671700_+	hypothetical protein	NA	NA	NA	NA
WP_002211935.1\|1673864_1675097_+	hypothetical protein	NA	NA	NA	NA
WP_002211936.1\|1675093_1678516_+	type VI secretion system membrane subunit	NA	NA	NA	NA
WP_002211937.1\|1678559_1680161_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_002211938.1\|1680178_1681237_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_002211939.1\|1681251_1681707_+	hypothetical protein	NA	NA	NA	NA
WP_002211940.1\|1681927_1683691_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_8

2089030 : 2188702

103

Escherichia_phage(15.38%)

transposase,integrase,lysis,tail,tRNA,holin

attL 2136398:2136428|attR 2178121:2178151

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|2089030_2090053_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|2090052_2090832_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210659.1\|2091200_2091791_-	thymidine kinase	A0A1Z1LYD5	Serratia_phage	1.5e-54	55.8
WP_002210661.1\|2092540_2092939_+	DNA-binding transcriptional regulator H-NS	NA	NA	NA	NA
WP_002210664.1\|2093373_2094720_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.9e-81	38.3
WP_002210665.1\|2095026_2096043_-	two-component system response regulator RssB	NA	NA	NA	NA
WP_002210666.1\|2097376_2097841_+	YchJ family protein	NA	NA	NA	NA
WP_002210667.1\|2097924_2098794_+	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	5.5e-13	37.3
WP_002209743.1\|2098756_2099965_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211665.1\|2100836_2101697_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211667.1\|2102506_2103313_+	exodeoxyribonuclease III	NA	NA	NA	NA
WP_002211668.1\|2103410_2103797_+	pyrimidine (deoxy)nucleoside triphosphate diphosphatase	NA	NA	NA	NA
WP_002211669.1\|2103809_2104100_-	DUF1496 domain-containing protein	NA	NA	NA	NA
WP_002211670.1\|2104096_2106022_-	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	4.2e-37	30.4
WP_002211671.1\|2106098_2107145_-	selenide, water dikinase SelD	NA	NA	NA	NA
WP_002211673.1\|2107369_2107921_-	NAD(P)H nitroreductase	NA	NA	NA	NA
WP_002211674.1\|2108083_2109934_+	signal peptide peptidase SppA	NA	NA	NA	NA
WP_002211675.1\|2110050_2111067_+	asparaginase	NA	NA	NA	NA
WP_002211676.1\|2111081_2111729_+	bifunctional nicotinamidase/pyrazinamidase	A0A2K9L6K4	Tupanvirus	1.8e-21	33.0
WP_002217933.1\|2111862_2112135_-	YeaC family protein	NA	NA	NA	NA
WP_002211677.1\|2112205_2112619_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_002224141.1\|2112966_2113962_+	glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_002211679.1\|2114275_2115151_+	D-hexose-6-phosphate mutarotase	NA	NA	NA	NA
WP_161992983.1\|2115223_2115973_-	MipA/OmpV family protein	NA	NA	NA	NA
WP_002211681.1\|2116416_2118351_+	protein kinase YeaG	NA	NA	NA	NA
WP_002216501.1\|2118500_2119775_+	YeaH/YhbH family protein	A0A140HLI1	Bacillus_phage	1.5e-11	37.1
WP_002211683.1\|2119882_2121001_+	DMT family transporter	NA	NA	NA	NA
WP_002211684.1\|2121035_2121941_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211685.1\|2122138_2123008_+	pirin family protein	NA	NA	NA	NA
WP_002216508.1\|2123272_2124475_+	multidrug effflux MFS transporter	S4TR35	Salmonella_phage	7.6e-29	29.1
WP_044023028.1\|2124490_2125762_-	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_002211687.1\|2126260_2127796_+	SpoVR family protein	NA	NA	NA	NA
WP_002211688.1\|2128013_2128733_-	fatty acid metabolism transcriptional regulator FadR	NA	NA	NA	NA
WP_002211689.1\|2128976_2130551_+	sodium/proton antiporter NhaB	NA	NA	NA	NA
WP_002227934.1\|2130786_2131317_+	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_002214494.1\|2131733_2132090_-	hypothetical protein	NA	NA	NA	NA
WP_002211692.1\|2133181_2133922_+	hypothetical protein	NA	NA	NA	NA
WP_002211693.1\|2133938_2135138_+	cysteine desulfurase	A0A1X7QGF3	Faustovirus	2.4e-38	29.6
WP_002214492.1\|2135141_2136314_+	MFS transporter	NA	NA	NA	NA
2136398:2136428	attL	NA	NA	NA	NA
WP_002209743.1\|2136618_2137827_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211695.1\|2138047_2138467_-\|tail	tail fiber assembly protein	B6SCW7	Bacteriophage	5.7e-08	42.0
WP_002211696.1\|2138477_2139395_-	hypothetical protein	NA	NA	NA	NA
WP_002211697.1\|2139411_2140410_-	hypothetical protein	NA	NA	NA	NA
WP_002211698.1\|2140409_2143613_-	host specificity protein J	F1C571	Cronobacter_phage	0.0e+00	60.5
WP_002359202.1\|2143788_2144010_+	hypothetical protein	NA	NA	NA	NA
WP_002211699.1\|2143978_2144143_-	hypothetical protein	NA	NA	NA	NA
WP_002211700.1\|2144184_2144805_-\|tail	tail assembly protein	K7PGY0	Enterobacteria_phage	3.2e-55	57.0
WP_002211701.1\|2144860_2145076_-	hypothetical protein	NA	NA	NA	NA
WP_002214482.1\|2145218_2145770_-	zinc ribbon domain-containing protein	S4TR42	Salmonella_phage	9.5e-27	58.0
WP_002211704.1\|2145868_2146876_-	Bro-N domain-containing protein	A0A2H4J0P1	uncultured_Caudovirales_phage	4.1e-36	33.0
WP_002211705.1\|2146949_2147117_-	hypothetical protein	G9L6D7	Escherichia_phage	5.2e-13	61.8
WP_002211706.1\|2147240_2147672_+	Arc family DNA-binding protein	G9L6D6	Escherichia_phage	2.5e-30	58.4
WP_002211707.1\|2147750_2148383_-	hypothetical protein	NA	NA	NA	NA
WP_002211708.1\|2148643_2149354_-	C40 family peptidase	K7P6F5	Enterobacteria_phage	1.3e-108	76.8
WP_002211709.1\|2149356_2150109_-\|tail	phage minor tail protein L	A0A1W6JNX9	Morganella_phage	9.4e-102	67.7
WP_002213759.1\|2150229_2150688_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002211710.1\|2150992_2151334_-\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	1.7e-21	50.0
WP_002211711.1\|2151336_2154840_-\|tail	phage tail tape measure protein	K7PMB9	Enterobacterial_phage	5.2e-118	33.2
WP_071525538.1\|2154840_2155101_-	DUF1799 domain-containing protein	A0A0S2SY90	Pseudomonas_phage	3.7e-13	50.0
WP_002211712.1\|2155148_2155460_-	hypothetical protein	I6PDG2	Cronobacter_phage	1.4e-30	58.3
WP_002211713.1\|2155472_2156393_-	Ig-like domain-containing protein	I6PBN6	Cronobacter_phage	4.4e-61	49.1
WP_002211714.1\|2156458_2156866_-	DUF4128 domain-containing protein	NA	NA	NA	NA
WP_002211715.1\|2156862_2157447_-	hypothetical protein	G8C7Q1	Escherichia_phage	3.6e-48	52.1
WP_002211716.1\|2157448_2157799_-	hypothetical protein	I6PD77	Cronobacter_phage	6.9e-31	56.0
WP_002211717.1\|2157800_2158055_-	hypothetical protein	J9Q7U0	Salmonella_phage	2.2e-18	53.1
WP_002211718.1\|2158051_2158534_-	hypothetical protein	G8C7P9	Escherichia_phage	6.4e-27	46.1
WP_002211719.1\|2158581_2159787_-	Ig-like domain-containing protein	A0A1B0VMF8	Pseudomonas_phage	1.8e-142	79.2
WP_002211720.1\|2159800_2160574_-	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	2.8e-69	62.3
WP_002211721.1\|2160695_2161808_-	hypothetical protein	I6PD76	Cronobacter_phage	6.0e-121	58.2
WP_002228446.1\|2161808_2162450_-	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	3.8e-59	54.1
WP_002228445.1\|2162468_2163197_-	hypothetical protein	A0A1B0VMH0	Pseudomonas_phage	4.6e-61	51.4
WP_002211722.1\|2163196_2164171_-	hypothetical protein	A0A1W6JNY3	Morganella_phage	2.3e-153	81.1
WP_002211723.1\|2165430_2166015_-	hypothetical protein	A0A0R6PHH0	Moraxella_phage	4.8e-69	70.7
WP_002211724.1\|2166018_2166468_-	DUF2280 domain-containing protein	I6S1P9	Salmonella_phage	1.0e-47	72.9
WP_002211725.1\|2166498_2167134_-	hypothetical protein	I6S676	Salmonella_phage	7.2e-87	71.4
WP_002211727.1\|2167590_2168304_-	phage antirepressor KilAC domain-containing protein	Q5MBW0	Stx1-converting_phage	7.6e-69	60.2
WP_002211729.1\|2168849_2169308_-\|lysis	lysis protein	A0A2H4JHL8	uncultured_Caudovirales_phage	4.9e-21	45.3
WP_002211730.1\|2169292_2169805_-	lysozyme	I6PBN2	Cronobacter_phage	9.7e-50	61.6
WP_002430108.1\|2169835_2170033_-\|holin	phage holin family protein	B6SD15	Bacteriophage	4.9e-18	64.4
WP_002215644.1\|2170278_2170554_+	hypothetical protein	NA	NA	NA	NA
WP_002211731.1\|2170550_2170760_-	hypothetical protein	NA	NA	NA	NA
WP_002393183.1\|2170922_2171099_+	hypothetical protein	NA	NA	NA	NA
WP_002211732.1\|2171183_2171747_-	Bro-N domain-containing protein	B6SD63	Bacteriophage	9.4e-30	58.0
WP_002215638.1\|2171795_2172014_-	ash family protein	NA	NA	NA	NA
WP_002215636.1\|2172017_2172407_-	antitermination protein	A0A1W6JNX1	Morganella_phage	1.4e-45	68.8
WP_002211735.1\|2172407_2173013_-	recombination protein NinG	A0A1P8DTE0	Proteus_phage	2.8e-56	56.9
WP_002211736.1\|2173086_2173533_-	recombination protein NinB	A0A2H4J8D9	uncultured_Caudovirales_phage	3.9e-47	62.5
WP_002215632.1\|2174557_2174818_+	excisionase family protein	Q859D3	Escherichia_coli_phage	1.7e-10	42.9
WP_001297096.1\|2174985_2175765_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|2175764_2176787_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002211738.1\|2176856_2178095_+\|integrase	site-specific integrase	Q20GI2	Phage_258-320	2.3e-121	53.3
WP_002211739.1\|2178121_2178568_-	YcgN family cysteine cluster protein	NA	NA	NA	NA
2178121:2178151	attR	NA	NA	NA	NA
WP_002211740.1\|2178670_2179327_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_002215627.1\|2179397_2180483_-	lytic murein transglycosylase	NA	NA	NA	NA
WP_002211743.1\|2180623_2180896_-	YcgL domain-containing protein	NA	NA	NA	NA
WP_002220631.1\|2181616_2182303_+	septum site-determining protein MinC	NA	NA	NA	NA
WP_002211179.1\|2182327_2183140_+	septum site-determining protein MinD	NA	NA	NA	NA
WP_002211180.1\|2183143_2183413_+	cell division topological specificity factor MinE	NA	NA	NA	NA
WP_002211181.1\|2183649_2184771_-	ribonuclease D	NA	NA	NA	NA
WP_002211182.1\|2184930_2186619_-	long-chain-fatty-acid--CoA ligase FadD	A0A2H4PQM9	Staphylococcus_phage	1.8e-31	28.9
WP_087768167.1\|2187153_2187261_+	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002211183.1\|2187261_2187867_-	Slp family lipoprotein	NA	NA	NA	NA
WP_002211184.1\|2188003_2188702_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA

DBSCAN-SWA_9

2561354 : 2600441

Escherichia_phage(14.29%)

transposase,coat,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|2561354_2562377_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002209743.1\|2563752_2564961_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002210829.1\|2565693_2566530_+	5-dehydro-4-deoxy-D-glucuronate isomerase	NA	NA	NA	NA
WP_002210830.1\|2566621_2567383_+	2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD	Q06VL0	Trichoplusia_ni_ascovirus	3.1e-20	32.9
WP_002210831.1\|2567718_2569386_+	pectate disaccharide-lyase	NA	NA	NA	NA
WP_002210832.1\|2569426_2570317_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_002210833.1\|2570309_2571230_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_002210834.1\|2571243_2572371_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	1.6e-12	26.5
WP_002210835.1\|2572386_2573679_+	carbohydrate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002210836.1\|2573976_2574687_+	porin	NA	NA	NA	NA
WP_002210837.1\|2575166_2575715_+	metal-dependent hydrolase	A0A127AVX7	Bacillus_phage	4.0e-09	32.9
WP_014462379.1\|2575918_2577310_+	L-cystine transporter	NA	NA	NA	NA
WP_002210839.1\|2577524_2578376_-	N-acetylmuramoyl-L-alanine amidase	A0A1W6DX33	Sphingobium_phage	1.3e-11	28.8
WP_002210840.1\|2578760_2579552_-	DNA-binding transcriptional regulator KdgR	NA	NA	NA	NA
WP_002210841.1\|2579738_2580905_-	oligogalacturonate lyase	NA	NA	NA	NA
WP_002210842.1\|2581231_2582599_+	MFS transporter	NA	NA	NA	NA
WP_002210843.1\|2582653_2583457_-	molecular chaperone	NA	NA	NA	NA
WP_002215120.1\|2583453_2584617_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002210844.1\|2584613_2587226_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002215118.1\|2587307_2588087_-	fimbrial chaperone	NA	NA	NA	NA
WP_002210846.1\|2588239_2588782_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002210847.1\|2589440_2590322_-\|protease	protease HtpX	NA	NA	NA	NA
WP_002210848.1\|2590795_2592868_-	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	4.0e-86	34.8
WP_002210849.1\|2592887_2593601_-	RNA chaperone ProQ	NA	NA	NA	NA
WP_002210850.1\|2593696_2594194_-	GAF domain-containing protein	NA	NA	NA	NA
WP_002216616.1\|2595642_2598294_+	PqiB family protein	NA	NA	NA	NA
WP_002210852.1\|2598772_2599327_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_044023075.1\|2599332_2599863_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002216611.1\|2599883_2600441_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_10

3205121 : 3274838

Escherichia_phage(25.0%)

transposase,tRNA,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_014462431.1\|3205121_3206003_-\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_002209726.1\|3206002_3207013_-	aspartate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_002209725.1\|3207182_3208310_-	4-phosphoerythronate dehydrogenase PdxB	A0A285PXZ1	Cedratvirus	6.1e-20	27.9
WP_002209724.1\|3208356_3209142_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002209722.1\|3209367_3210285_+	DMT family transporter	NA	NA	NA	NA
WP_002209721.1\|3210569_3211607_+	flagella biosynthesis regulator Flk	NA	NA	NA	NA
WP_002209720.1\|3211948_3212479_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002209718.1\|3213269_3213962_+	aspartate/glutamate racemase family protein	NA	NA	NA	NA
WP_002209717.1\|3214369_3215593_-	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_002209715.1\|3218010_3218289_-	YfcL family protein	NA	NA	NA	NA
WP_002209714.1\|3218346_3218889_-	elongation factor P hydroxylase	NA	NA	NA	NA
WP_002209713.1\|3218988_3219795_-	TSUP family transporter	NA	NA	NA	NA
WP_002209711.1\|3220630_3221716_-	chorismate synthase	A0A291AU41	Pandoravirus	2.7e-89	47.4
WP_002227846.1\|3223095_3223626_+	endonuclease SmrB	NA	NA	NA	NA
WP_128888912.1\|3223822_3224020_-	hypothetical protein	NA	NA	NA	NA
WP_002209707.1\|3224099_3224591_-	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_002209705.1\|3225159_3227484_-	fatty acid oxidation complex subunit alpha FadJ	NA	NA	NA	NA
WP_002209704.1\|3227483_3228794_-	acetyl-CoA C-acyltransferase FadI	NA	NA	NA	NA
WP_002227845.1\|3229080_3229377_-	YfcZ/YiiS family protein	NA	NA	NA	NA
WP_002209702.1\|3229790_3231056_+	long-chain fatty acid transporter FadL	NA	NA	NA	NA
WP_002209701.1\|3231162_3231927_-	phospholipid-binding lipoprotein MlaA	NA	NA	NA	NA
WP_002209700.1\|3231962_3233189_-	c-type cytochrome biogenesis protein CcmI	NA	NA	NA	NA
WP_002214855.1\|3233188_3233701_-	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_002209699.1\|3233697_3234264_-	DsbE family thiol:disulfide interchange protein	NA	NA	NA	NA
WP_002209698.1\|3234260_3236231_-	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_002209697.1\|3236227_3236722_-	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_002209696.1\|3236718_3237021_-	heme exporter protein CcmD	NA	NA	NA	NA
WP_002209695.1\|3237017_3237755_-	heme ABC transporter permease	NA	NA	NA	NA
WP_002209694.1\|3237817_3238477_-	heme exporter protein CcmB	NA	NA	NA	NA
WP_002209693.1\|3238446_3239103_-	cytochrome c biogenesis heme-transporting ATPase CcmA	A0A1V0SE00	Indivirus	4.8e-09	24.7
WP_002209692.1\|3239547_3240015_-	hypothetical protein	NA	NA	NA	NA
WP_002209691.1\|3240630_3241173_+	LemA family protein	NA	NA	NA	NA
WP_002209690.1\|3241177_3243217_+	DUF2207 domain-containing protein	NA	NA	NA	NA
WP_002209688.1\|3243592_3243934_+	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_002209687.1\|3244008_3244356_-	hypothetical protein	NA	NA	NA	NA
WP_002209686.1\|3244380_3244860_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002209685.1\|3244972_3245779_-	ImpE family protein	NA	NA	NA	NA
WP_002354537.1\|3245798_3246641_-	TagK domain-containing protein	NA	NA	NA	NA
WP_002209684.1\|3246646_3246907_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_044023133.1\|3247005_3249501_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	3.2e-29	23.1
WP_002214843.1\|3249794_3253622_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_001297096.1\|3254482_3255262_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|3255261_3256284_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002211571.1\|3256962_3258312_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002211572.1\|3258315_3258855_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002211573.1\|3259128_3259614_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_002211574.1\|3259939_3261442_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002211575.1\|3261465_3261990_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002211576.1\|3262094_3262703_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002211577.1\|3262687_3263878_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002209743.1\|3263902_3265111_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002215157.1\|3265132_3266683_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002211579.1\|3266810_3267572_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_002211580.1\|3267728_3268274_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002215317.1\|3268474_3271150_-	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	1.0e-81	32.3
WP_002211582.1\|3271932_3273813_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002211583.1\|3273812_3274838_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_11

3924088 : 3984714

Escherichia_phage(14.29%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213775.1\|3924088_3924547_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210156.1\|3924742_3925195_-	50S ribosomal protein L9	NA	NA	NA	NA
WP_002210155.1\|3925234_3925462_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_002210154.1\|3925466_3925787_-	primosomal replication protein N	NA	NA	NA	NA
WP_002210153.1\|3925792_3926185_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_002210152.1\|3926551_3927253_-	esterase	NA	NA	NA	NA
WP_000255944.1\|3927309_3928332_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3928331_3929111_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210151.1\|3930191_3931085_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002210150.1\|3931346_3932051_+	pirin family protein	NA	NA	NA	NA
WP_002210149.1\|3932988_3933888_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.0e-49	44.4
WP_002228200.1\|3933950_3935924_+	penicillin-binding protein activator	NA	NA	NA	NA
WP_002210147.1\|3936007_3936361_+	YraN family protein	NA	NA	NA	NA
WP_002210145.1\|3937231_3937807_+	divisome-associated lipoprotein YraP	NA	NA	NA	NA
WP_002210144.1\|3938013_3938739_-	monofunctional biosynthetic peptidoglycan transglycosylase	NA	NA	NA	NA
WP_002210143.1\|3938735_3939389_-	isoprenoid biosynthesis glyoxalase ElbB	NA	NA	NA	NA
WP_002210142.1\|3939629_3941966_-	aerobic respiration two-component sensor histidine kinase ArcB	A0A1V0SGX0	Hokovirus	9.9e-41	30.4
WP_002210140.1\|3942229_3943153_-	TIGR01212 family radical SAM protein	NA	NA	NA	NA
WP_002228691.1\|3943975_3948433_+	glutamate synthase large subunit	NA	NA	NA	NA
WP_002210138.1\|3948442_3949861_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_002210137.1\|3950301_3950787_+	hypothetical protein	NA	NA	NA	NA
WP_002216203.1\|3950939_3951455_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	3.6e-28	55.6
WP_002210135.1\|3951460_3952102_-	stringent starvation protein A	NA	NA	NA	NA
WP_002230558.1\|3952281_3952479_+	hypothetical protein	NA	NA	NA	NA
WP_002210133.1\|3952475_3952868_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_002210132.1\|3952882_3953311_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_002210130.1\|3954976_3955381_+	DUF1043 family protein	NA	NA	NA	NA
WP_002218066.1\|3955651_3957025_+\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	7.4e-20	28.2
WP_002213775.1\|3957141_3957600_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210128.1\|3957825_3958914_+	outer membrane-stress sensor serine endopeptidase DegS	A0A1B1IRD3	uncultured_Mediterranean_phage	2.1e-09	31.8
WP_002210127.1\|3959094_3960357_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_002210126.1\|3960510_3960765_-	BolA family iron metabolism protein IbaG	NA	NA	NA	NA
WP_002210125.1\|3960911_3961214_-	lipid asymmetry maintenance protein MlaB	NA	NA	NA	NA
WP_002210124.1\|3961249_3961873_-	phospholipid-binding protein MlaC	NA	NA	NA	NA
WP_002210123.1\|3961885_3962443_-	outer membrane lipid asymmetry maintenance protein MlaD	NA	NA	NA	NA
WP_002210122.1\|3962447_3963230_-	lipid asymmetry maintenance ABC transporter permease subunit MlaE	NA	NA	NA	NA
WP_002210121.1\|3963447_3964266_-	phospholipid ABC transporter ATP-binding protein MlaF	G3M9Y6	Bacillus_virus	2.2e-19	31.7
WP_002210120.1\|3964530_3965505_+	calcium/sodium antiporter	NA	NA	NA	NA
WP_002210119.1\|3965615_3966602_+	arabinose-5-phosphate isomerase KdsD	A0A2P0VNK5	Tetraselmis_virus	6.0e-40	30.8
WP_002228203.1\|3966850_3967414_+	3-deoxy-manno-octulosonate-8-phosphatase KdsC	A0A140XBD6	Dickeya_phage	9.6e-59	83.0
WP_002218352.1\|3967410_3967974_+	LPS export ABC transporter periplasmic protein LptC	NA	NA	NA	NA
WP_002210117.1\|3967957_3968503_+	lipopolysaccharide ABC transporter substrate-binding protein LptA	NA	NA	NA	NA
WP_002210116.1\|3968509_3969235_+	LPS export ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-22	28.4
WP_002210115.1\|3969296_3970730_+	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_002213952.1\|3971158_3971641_+	PTS IIA-like nitrogen regulatory protein PtsN	NA	NA	NA	NA
WP_002210113.1\|3971946_3972801_+	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-05	30.0
WP_002210112.1\|3972797_3973070_+	PTS phosphocarrier protein NPr	NA	NA	NA	NA
WP_002210111.1\|3973407_3974343_+	aspartate carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	1.5e-48	38.5
WP_002210110.1\|3974354_3974819_+	aspartate carbamoyltransferase regulatory subunit	NA	NA	NA	NA
WP_002210109.1\|3974956_3975343_+	2-iminobutanoate/2-iminopropanoate deaminase	NA	NA	NA	NA
WP_002210107.1\|3975641_3976118_+	PliI family lysozyme inhibitor of I-type lysozyme	NA	NA	NA	NA
WP_002210106.1\|3976350_3977304_+	HTH-type transcriptional regulator TreR	NA	NA	NA	NA
WP_002215779.1\|3977714_3979130_+	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
WP_002210104.1\|3979224_3980892_+	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
WP_002210103.1\|3981244_3981655_+	nucleoside diphosphate kinase regulator	NA	NA	NA	NA
WP_002210102.1\|3981886_3982273_-	cytochrome b562	NA	NA	NA	NA
WP_011055205.1\|3982480_3983125_-	hypothetical protein	A0A1B0VBK8	Salmonella_phage	3.4e-52	49.0
WP_002210100.1\|3983373_3984714_-\|protease	metalloprotease PmbA	NA	NA	NA	NA

DBSCAN-SWA_12

4104266 : 4186712

Bacillus_phage(18.18%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002212105.1\|4104266_4105613_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002212104.1\|4105615_4106161_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002212103.1\|4106160_4107477_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_002213885.1\|4107602_4108691_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_100067904.1\|4109448_4110802_+\|transposase	IS3-like element IS1661 family transposase	A0A1B1P773	Bacillus_phage	1.1e-55	44.7
WP_002212100.1\|4111918_4112359_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002212099.1\|4112365_4113847_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002212098.1\|4113914_4114412_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002212097.1\|4114935_4115454_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002212095.1\|4115605_4115884_-	hypothetical protein	NA	NA	NA	NA
WP_002212093.1\|4116354_4117266_-	maltose operon protein MalM	NA	NA	NA	NA
WP_002212092.1\|4117506_4118778_-	maltoporin	NA	NA	NA	NA
WP_002212091.1\|4118848_4119958_-	maltose/maltodextrin ABC transporter ATP-binding protein MalK	G9BWD6	Planktothrix_phage	5.0e-27	35.5
WP_002221973.1\|4119961_4120198_-	hypothetical protein	NA	NA	NA	NA
WP_002212089.1\|4120759_4121971_+	maltose/maltodextrin ABC transporter substrate-binding protein MalE	NA	NA	NA	NA
WP_002212088.1\|4122157_4123735_+	maltose ABC transporter permease MalF	NA	NA	NA	NA
WP_002212087.1\|4123748_4124639_+	maltose ABC transporter permease MalG	NA	NA	NA	NA
WP_002212086.1\|4124781_4125189_-	phosphate-starvation-inducible protein PsiE	NA	NA	NA	NA
WP_002212084.1\|4127340_4128726_+	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
WP_002212081.1\|4131052_4135960_+	hemagglutinin repeat-containing protein	NA	NA	NA	NA
WP_002212080.1\|4136055_4139751_-	methionine synthase	A0A140XBC7	Dickeya_phage	4.6e-24	82.5
WP_044023199.1\|4140929_4142657_-	bifunctional isocitrate dehydrogenase kinase/phosphatase	NA	NA	NA	NA
WP_002212078.1\|4142912_4144220_-	isocitrate lyase	NA	NA	NA	NA
WP_002212077.1\|4144266_4145865_-	malate synthase A	NA	NA	NA	NA
WP_002212076.1\|4146285_4147215_-	homoserine O-succinyltransferase	NA	NA	NA	NA
WP_002210691.1\|4155646_4156933_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002355296.1\|4157080_4157734_-	DUF1481 domain-containing protein	NA	NA	NA	NA
WP_002210689.1\|4157783_4158059_-	DNA-binding protein HU-alpha	A7KV42	Bacillus_phage	3.6e-19	55.6
WP_002210688.1\|4158247_4158838_-	YjaG family protein	NA	NA	NA	NA
WP_014462494.1\|4158883_4159624_-	deoxyribonuclease V	NA	NA	NA	NA
WP_002210685.1\|4160840_4161626_-	hypothetical protein	NA	NA	NA	NA
WP_002210684.1\|4161718_4162501_-	NAD(+) diphosphatase	NA	NA	NA	NA
WP_002210683.1\|4162597_4163107_+	sigma D regulator	NA	NA	NA	NA
WP_002210682.1\|4163482_4165528_+	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_002210681.1\|4165514_4166189_+	thiamine phosphate synthase	NA	NA	NA	NA
WP_002210680.1\|4166178_4166976_+	HesA/MoeB/ThiF family protein	A0A1V0SAV8	Catovirus	1.6e-11	27.8
WP_002217275.1\|4166972_4167188_+	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_002228257.1\|4167189_4168005_+	thiazole synthase	NA	NA	NA	NA
WP_002210678.1\|4167997_4169128_+	2-iminoacetate synthase ThiH	NA	NA	NA	NA
WP_002213775.1\|4169559_4170018_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210677.1\|4170144_4174365_-	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	8.5e-67	27.0
WP_002210676.1\|4174493_4178522_-	DNA-directed RNA polymerase subunit beta	A0A0N9R0J7	Chrysochromulina_ericina_virus	1.2e-22	29.0
WP_002210675.1\|4178864_4179233_-	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_002210674.1\|4179299_4179797_-	50S ribosomal protein L10	NA	NA	NA	NA
WP_002210673.1\|4180161_4180866_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_002210672.1\|4180869_4181298_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_002210671.1\|4181488_4182034_-	transcription termination/antitermination protein NusG	A0A291AUS6	Sinorhizobium_phage	5.9e-13	28.3
WP_002210670.1\|4182035_4182419_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_002210669.1\|4182669_4183854_-	elongation factor Tu	A0A2K9L516	Tupanvirus	2.0e-13	26.9
WP_001297096.1\|4184910_4185690_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|4185689_4186712_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0

Anti-CRISPR protein detection

Acr_ID: NC_017160.1|WP_002214494.1|2131733_2132090_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_017160.1|WP_002214494.1|2131733_2132090_-|hypothetical-protein

2131733_2132090_-

118 aa aa

2089030-2188702

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location
NC_017160_3	TypeI-F	3.1\|2839804\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839804-2839835	32	2162002-2161971
NC_017160_3	TypeI-F	3.2\|2839864\|32\|NC_017160\|PILER-CR,CRISPRCasFinder,CRT	2839864-2839895	32	2166349-2166380
NC_017160_4	Orphan	4.4\|2876804\|32\|NC_017160\|CRISPRCasFinder,CRT	2876804-2876835	32	2160815-2160784

1. spacer 3.1|2839804|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NC_017160 position: 2162002-2161971, mismatch: 0

gtcaggaatttattcaacgtgttgcagactca	CRISPR spacer
gtcaggaatttattcaacgtgttgcagactca	Protospacer
********************************

2. spacer 3.2|2839864|32|NC_017160|PILER-CR,CRISPRCasFinder,CRT matches to NC_017160 position: 2166349-2166380, mismatch: 0

ctgatgggtaactttaatcccaaattcttttt	CRISPR spacer
ctgatgggtaactttaatcccaaattcttttt	Protospacer
********************************

3. spacer 4.4|2876804|32|NC_017160|CRISPRCasFinder,CRT matches to NC_017160 position: 2160815-2160784, mismatch: 0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

3. NC_017158

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

86 : 41984

Salmonella_phage(87.5%)

transposase,tail,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|86_1109_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|1108_1888_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002211769.1\|2021_2630_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	4.8e-64	62.2
WP_002211770.1\|2931_5820_-\|tail	phage tail protein	J9Q6E3	Salmonella_phage	4.5e-11	33.1
WP_002211771.1\|5900_6479_-	DUF4376 domain-containing protein	Q9LA61	Enterobacterial_phage	3.4e-27	38.8
WP_002214118.1\|6535_11167_-	DUF1983 domain-containing protein	J9Q713	Salmonella_phage	0.0e+00	88.6
WP_002211773.1\|11188_11776_-\|tail	tail assembly protein	J9Q7F8	Salmonella_phage	5.1e-103	92.8
WP_002211774.1\|11763_12561_-	C40 family peptidase	J9Q7R4	Salmonella_phage	1.4e-156	96.2
WP_002211775.1\|12553_13252_-\|tail	phage minor tail protein L	J9Q7Y5	Salmonella_phage	7.1e-136	99.1
WP_000440566.1\|13341_13677_-\|tail	phage tail protein	J9Q6E1	Salmonella_phage	5.7e-59	97.3
WP_002211776.1\|13718_18296_-	tape measure protein	J9Q712	Salmonella_phage	0.0e+00	90.5
WP_000952684.1\|18303_18528_-	hypothetical protein	J9Q7F7	Salmonella_phage	4.2e-34	100.0
WP_000163862.1\|18653_18971_-	hypothetical protein	J9Q7R3	Salmonella_phage	6.0e-50	98.1
WP_002211778.1\|19030_19777_-	Ig domain-containing protein	J9Q7Y4	Salmonella_phage	5.2e-129	98.8
WP_002211779.1\|19851_20235_-	hypothetical protein	J9Q6D8	Salmonella_phage	1.1e-66	98.4
WP_002211780.1\|20236_20710_-	hypothetical protein	J9Q711	Salmonella_phage	8.9e-82	99.4
WP_001027662.1\|20700_21045_-	hypothetical protein	J9Q7F6	Salmonella_phage	1.9e-57	100.0
WP_002211781.1\|21142_21976_-	hypothetical protein	J9Q7R2	Salmonella_phage	2.9e-152	99.6
WP_002211782.1\|21975_22410_-	hypothetical protein	J9Q7Y3	Salmonella_phage	3.1e-73	99.3
WP_002211783.1\|22453_23116_-	Ig domain-containing protein	J9Q6D6	Salmonella_phage	8.5e-107	97.2
WP_002211784.1\|23190_24066_-	hypothetical protein	J9Q710	Salmonella_phage	8.5e-163	99.7
WP_002211785.1\|24092_24926_-	hypothetical protein	J9Q7F4	Salmonella_phage	5.8e-137	91.3
WP_002211786.1\|24948_26523_-	hypothetical protein	J9Q7R1	Salmonella_phage	2.4e-301	99.2
WP_002211787.1\|26556_27813_-\|terminase	terminase	J9Q7Y2	Salmonella_phage	1.8e-251	100.0
WP_002211788.1\|27815_28457_-	hypothetical protein	J9Q6D4	Salmonella_phage	1.2e-108	98.1
WP_000176291.1\|28652_28919_-	hypothetical protein	J9Q757	Salmonella_phage	1.3e-42	100.0
WP_002211790.1\|29823_30078_-	hypothetical protein	J9Q7U0	Salmonella_phage	2.0e-40	97.6
WP_002211791.1\|30070_30709_-	ATP-binding cassette domain-containing protein	J9Q807	Salmonella_phage	4.7e-110	98.1
WP_002211792.1\|30705_31374_-	ParB N-terminal domain-containing protein	J9Q6L1	Salmonella_phage	9.5e-114	98.2
WP_002228791.1\|31373_32072_-	ParB N-terminal domain-containing protein	J9Q756	Salmonella_phage	9.6e-125	98.7
WP_002211794.1\|32136_33696_+	DEAD/DEAH box helicase	J9Q7I4	Salmonella_phage	1.1e-293	99.0
WP_002214131.1\|33698_33977_+	hypothetical protein	J9Q7T9	Salmonella_phage	4.4e-41	97.8
WP_002211796.1\|34036_34459_+	hypothetical protein	J9Q806	Salmonella_phage	4.1e-62	85.0
WP_002211799.1\|35313_35964_+	hypothetical protein	J9Q754	Salmonella_phage	4.1e-114	99.5
WP_002214137.1\|36048_36276_+	hypothetical protein	NA	NA	NA	NA
WP_002211801.1\|36913_37396_-	hypothetical protein	J9Q805	Salmonella_phage	5.1e-85	94.4
WP_002211802.1\|37601_37883_-	hypothetical protein	J9Q753	Salmonella_phage	6.1e-46	93.5
WP_002213759.1\|38082_38541_-\|transposase	IS200/IS605-like element IS1541A family transposase	D9CGB6	Hyperthermophilic_Archaeal_Virus_2	5.0e-13	35.3
WP_002214145.1\|38749_39319_-	hypothetical protein	J9Q7Z7	Salmonella_phage	5.8e-104	100.0
WP_002213303.1\|39331_40078_-	hypothetical protein	J9Q6J5	Salmonella_phage	4.1e-134	96.4
WP_002214148.1\|40067_41984_-	AAA family ATPase	J9Q741	Salmonella_phage	0.0e+00	98.6

DBSCAN-SWA_2

45097 : 65976

Salmonella_phage(94.74%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002214160.1\|45097_45742_-	hypothetical protein	J9Q739	Salmonella_phage	1.8e-122	98.1
WP_002214164.1\|46486_47551_+	replication protein RepA	J9Q7H0	Salmonella_phage	2.4e-188	98.6
WP_002222711.1\|47955_48168_-	hypothetical protein	J9Q7S8	Salmonella_phage	6.8e-34	95.7
WP_002227818.1\|48167_48503_-	hypothetical protein	J9Q7Z5	Salmonella_phage	5.2e-52	91.0
WP_002228796.1\|48499_48679_-	hypothetical protein	J9Q6J1	Salmonella_phage	5.8e-18	86.4
WP_002228797.1\|48719_48995_-	hypothetical protein	J9Q738	Salmonella_phage	1.7e-45	95.6
WP_002222869.1\|49062_49473_-	hypothetical protein	J9Q7G9	Salmonella_phage	4.1e-75	97.8
WP_002222868.1\|49456_49828_-	DUF2591 domain-containing protein	J9Q7S7	Salmonella_phage	4.0e-61	87.8
WP_002222866.1\|49982_50813_-	hypothetical protein	J9Q7Z4	Salmonella_phage	9.3e-127	98.6
WP_002213439.1\|50816_51017_-	hypothetical protein	J9Q6J0	Salmonella_phage	1.1e-25	97.0
WP_000920226.1\|52186_52453_-	hypothetical protein	J9Q7G8	Salmonella_phage	1.6e-40	100.0
WP_002225551.1\|52452_53397_-	exonuclease	J9Q7S6	Salmonella_phage	1.3e-180	99.0
WP_001297096.1\|55329_56109_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002213135.1\|56563_56995_-	hypothetical protein	J9Q6I8	Salmonella_phage	2.6e-72	98.6
WP_002215095.1\|57215_57467_+	hypothetical protein	NA	NA	NA	NA
WP_002213141.1\|57539_58103_+	DNA-binding protein	J9Q7G7	Salmonella_phage	2.2e-63	64.6
WP_002213143.1\|58132_58576_-	hypothetical protein	J9Q7S4	Salmonella_phage	7.8e-72	100.0
WP_002221186.1\|58572_62097_-	DNA polymerase III subunit alpha	J9Q7Z2	Salmonella_phage	0.0e+00	99.2
WP_002211767.1\|62277_63513_-	AAA family ATPase	J9Q733	Salmonella_phage	3.0e-238	99.3
WP_002211766.1\|63609_65976_-	porphyrin biosynthesis protein	J9Q7G6	Salmonella_phage	0.0e+00	94.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_017157

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_017160

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information

3. NC_017158

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection