CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number
NC_011727	Rippkaea orientalis PCC 8801 plasmid pP880103, complete sequence	1 crisprs	NA	0	1	0
NC_011721	Rippkaea orientalis PCC 8801 plasmid pP880101, complete sequence	0 crisprs	NA	0	0	0
NC_011723	Rippkaea orientalis PCC 8801 plasmid pP880102, complete sequence	0 crisprs	cas14j	0	0	0
NC_011726	Rippkaea orientalis PCC 8801, complete sequence	13 crisprs	cas14j,cas2,cas1,cas4,cas6,csc1gr5,csc2gr7,cas10d,cas3,WYL,PD-DExK,2OG_CAS,csa3,c2c9_V-U4,c2c10_CAS-V-U3,DinG,RT,cas8b3,cas7,cas5,Cas14c_CAS-V-F,c2c5_V-U5,c2c8_V-U2	1	11	5

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

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CRISPR-Cas detection and classification

Crispr_ID: NC_011727_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011727_1

1056-1161

Orphan

Consensus_repeat	Method
GACTCCTTGTGTACCAAGTCTGGGGGGACAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011727_1

>merge|NC_011727|1|1056-1161|CRISPRCasFinder
GACTCCTTGTGTACCAAGTCTGGGGGGACAGAACTTCTCTTTTGTATACACTCTTTAGCGTGTCCTGTCCCTAGTGACTCCTTGTGTACTAAGTCTGGGGGGACAG

>NC_011727|1|1|1056-1161|CRISPRCasFinder
GACTCCTTGTGTACCAAGTCTGGGGGGACAG	AACTTCTCTTTTGTATACACTCTTTAGCGTGTCCTGTCCCTAGT
GACTCCTTGTGTACTAAGTCTGGGGGGACAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_011727.1\|WP_012597292.1\|5341_9799_+\|RHS-repeat-associated-core-domain-containing-protein	unknown	unknown	gnl\|CDD\|225750
NC_011727.1\|WP_012597289.1\|302_710_+\|hypothetical-protein	unknown	unknown	unknown
NC_011727.1\|WP_012597294.1\|11270_12215_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|274042
NC_011727.1\|WP_012597291.1\|4566_4851_-\|hypothetical-protein	unknown	unknown	unknown
NC_011727.1\|WP_012597298.1\|13802_16559_+\|DUF3991-domain-containing-protein	unknown	unknown	gnl\|CDD\|379044
NC_011727.1\|WP_012597295.1\|12340_12925_+\|hypothetical-protein	unknown	unknown	unknown
NC_011727.1\|WP_012597288.1\|47_284_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NC_011727.1\|WP_012597293.1\|9833_10727_+\|hypothetical-protein	unknown	unknown	unknown
NC_011727.1\|WP_012597297.1\|13419_13785_+\|MobC-family-plasmid-mobilization-relaxosome-protein	unknown	unknown	gnl\|CDD\|368576

Protein	Function_ID	Function_description	E-value
NC_011727.1\|WP_012597292.1\|5341_9799_+\|RHS-repeat-associated-core-domain-containing-protein	gnl\|CDD\|225750	COG3209, RhsA, Rhs family protein [Cell envelope biogenesis, outer membrane].	1.01755e-25
NC_011727.1\|WP_012597297.1\|13419_13785_+\|MobC-family-plasmid-mobilization-relaxosome-protein	gnl\|CDD\|368576	pfam05713, MobC, Bacterial mobilisation protein (MobC). This family consists of several bacterial MobC-like, mobilisation proteins. MobC proteins belong to the group of relaxases. Together with MobA and MobB they bind to a single cis-active site of a mobilising plasmid, the origin of transfer (oriT) region. The absence of MobC has several different effects on oriT DNA. Site- and strand-specific nicking by MobA protein is severely reduced, accounting for the lower frequency of mobilisation. The localized DNA strand separation required for this nicking is less affected, but becomes more sensitive to the level of active DNA gyrase in the cell. In addition, strand separation is not efficiently extended through the region containing the nick site. These effects suggest a model in which MobC acts as a molecular wedge for the relaxosome-induced melting of oriT DNA. The effect of MobC on strand separation may be partially complemented by the helical distortion induced by supercoiling. However, MobC extends the melted region through the nick site, thus providing the single-stranded substrate required for cleavage by MobA.	9.97053e-10
NC_011727.1\|WP_012597288.1\|47_284_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	6.04537e-19
NC_011727.1\|WP_012597298.1\|13802_16559_+\|DUF3991-domain-containing-protein	gnl\|CDD\|379044	pfam13155, Toprim_2, Toprim-like. This is a family or Toprim-like proteins.	1.50211e-22
NC_011727.1\|WP_012597294.1\|11270_12215_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	1.72101e-33

>NC_011727.1|WP_012597289.1|302_710_+|hypothetical-protein
MGKAKRRKKLTPTHGKGFGSKNQQSLNLFLMGDIGLKCYEIYGRGILFNIPHSAPKYVLSSCSWLKLQEIELINTYNPSEEVILAEFIEPLKSSGRMVKSFSFELANQMRVFSTHQTIEELVSKMFVATADNEPS
>NC_011727.1|WP_012597288.1|47_284_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MTVHKTNNERIVFLYPDEDGYIIAEVPSLPGCISQGETRQEALQNIQEAIALHLEVLQERGELIPEDNIEITSVPVLI
>NC_011727.1|WP_012597291.1|4566_4851_-|hypothetical-protein
MPKSLTTSEPNILRPEDFDPPLKRKEPSLPGYWTLKEIATELNISFRRVGYDITGYPQKNIEPSLKAFKVGPIFLVSDENALEYIKRYRERKKS
>NC_011727.1|WP_012597292.1|5341_9799_+|RHS-repeat-associated-core-domain-containing-protein
MTTTLEVLDFNDVDAPIINFPRLANNTITSPIEIIGTVTDYDEDNHDTLQYYTLEVAKLGTDDFQEVFKGTKSVNNGVLGIFDPSLLENDAYTLRLKAVDRGGNLVFEERTINVEGDLKLGNFQLSFTDLSIPVAGIPISITRTYDTLTAQERDDFGYGWRLEFRDTNLRTSLGKDDYYETFDIIGQGFKEGDKVYLTLPGGKREAFTFKPELDRLGAFLQGAAAGLGLGEDPGLYHPKFVSESDSNNVLTVKDVLIIRTANGDFAGLAGNLYNPVDPYFGGQYTLTTGEGIVYEIEAETGDLLTVTDTNNNRLTFSENGIKSETGVEVKFNRDAKGRITSIVDPMGNVIKYDYDGHGDLIKVIDREENETKFDYSEERKHYLERIIDPLNREAVRTEYDETGRLKKVIDVNGEAVELVYDVDNSTQTTKGEEGYTTTYTYDEKGNKLTETDALGNTTYYTYGKLNRLLSETDAKGNTTTYDYGVRTGNLLSTKDALGNITKFSYDSRGNLVSLTDAANNITKFEYDLQGNVTKIIDANGHETHYTYDSNGNQLTESKTVTTAQGLVTVLTQNTYDKQGNLLSVTDAENNPTYYEYNELNQQTAVTDTLLRKTEYRYDNKGQLVETIYPDSTPNNNADNPRTITVYDRGSRQKATIDQAGRVTYYNYDQLGRLIETIYPDEVDTLSQFVSFLDSSKTVTTIDWTEVIYPDSNPSYLSDNPRTQTEYYQDGQVKANINERGYRTEYIYDANDQLIEIIYPELEYNPGINFTTTSTYDVVGRKIAETDGLGRTTNYVYDELGRLTKTLFADGTFTTSTYDKLGRRITTTDQEGKVTNYEYDSLGRLTDVVQYLNQNSLNPTEIRTEYGYDELGRLIWVEDANDHKTNYEYDKLGRRTDIELPLGQRSTTSYDEVGNIETVTDFNEKIITYFYDEQNRLIKKLFADNSSVDYTYTLTGLRETITDSRGTTTYTYDERDRLIAQTDPTGVYLNSGNTLEYSYDLTGNRTSVTTPSGTVYYTFDEWNRLKTVTDADNHQTIYVYDGVSNLIETTFSNGVIETRDYDDLNRLIKLENKLGNQVISGYEYTLDKVGNRLKVKEADGRIVEYEYDDLYRLIEEKITDSLDTVNDGRVISYTYDAVGNRLTKVDSVEGTTTYDYNANDWLLTETEENGDVKEYEYDETTFYQVDGLGSTRILTNEKGELINTYDYDAFGNLIESTGDIENNYLFAGEQFDENLGEYYLRQRYYNQEVGRFTRRDTYEGSLNNPVSLHKYLYANANPVIYIDPTGLYTLTEFSAGQAIADALAISLGISGFISNSYNPERLGGFGENEKPSTVLDRLLIWRNTWAPESIGGFGENLQPTFPNHTGHSNRDINDLIRYIFAISDPFELSNDIAYGHAWNAARNLEWAKLGINSQQQLADLIYDIVIFYEQKKVDGDKIIYLGSDGTIVIDNPRDPDGGTAFNPNIQQGNSQASQIYFDEQPGRVVD
>NC_011727.1|WP_012597293.1|9833_10727_+|hypothetical-protein
MKIITITYQKAKIQLSFQELTVFGNILNEVYKALHELEFETRVGVTFRQARSFLSSFTQESEQTGEQLIAISLSLSEISLLNNLLNEVCYGIKLQNFETKVGMTEEEVKQFLNLVNQAMKEMDLIREERKKTKIPSPSDSREIDNICSLEAEGYQVTFYFKKMAGNLNNIGVFIVLRFTSFNSVELMISSLPKSMSMENLEEFINNLEKYLEFSKEPTSDLVIPFQIFQNNIFQVQALERGITLDNEEYVNLNFMISLAQARGNIIKPSIGVQAAVLLKNIRSFISSMQKIIIDLKN
>NC_011727.1|WP_012597294.1|11270_12215_+|tyrosine-type-recombinase/integrase
MSGSPAKKAPRHQSLTSPTDLQNVRVEEFLATKALSPNSQKAYRRELLTFLAIVNKPFARIQSRHIVQYKVQLTEKLAPSSVNRALSALSSFFDWLEEAYGNPNPTLTIRQNKLPLPPARDLSDAELEALFEALENRPNLTKVRDKAVFAALRHGLRAGEVASLNLGDYDGIRLHIRVAKDDSSGHVPLDAPGRDAINTYLQQRRETGESFNPTSPLFLSHSPVPNTPPRFGYQGIYYFIKELGEMAGVANLTPHRLRHTFATQLLLTGMEPLHARTLTRHKSEVSFKRYAKRALEAAAERAFYRAIGEEPPTL
>NC_011727.1|WP_012597295.1|12340_12925_+|hypothetical-protein
MNVKELCDRYSLQSRKSLYSRLEAVGLKLPKDDDGRAYATEQILEQLDDLDLHLKNGGSLKNYTPVTSVTTQLETTENAYFLENTTQTTQLTTQTTTQLSREELLEIIEVLGSAIASRLQPIDPIAYNHSLEQAQQNNWILSSSEVKQLIGIKPSCPKGENVFTRGCWAFTKAGKIGNQTGWRVKKILEGDGHK
>NC_011727.1|WP_012597297.1|13419_13785_+|MobC-family-plasmid-mobilization-relaxosome-protein
MTTAKRDANLTIRLSQTEKLAWQEKADLVGMTLSDLIRQAISRTKTWTVADKSLMKEQTRQIARIGNNLNQIARWANTYKSTAEAIEIIQALRLIEQSLNQLSIKANQSSSPSPNSKDIDD
>NC_011727.1|WP_012597298.1|13802_16559_+|DUF3991-domain-containing-protein
MLLKFFNRGTGKGKGPVEYILNATDTKGIPREPQPELLKGNPQQIITLIDSLDFKHKYTSGVISFAPTDAPTNEQLEAIITSFEDTAFAGLEPDQYDILWVKHTHTGGGATALAERGRVELHFVTPRVELTTGKSLNIAPPGANYYFEPWRDYWNMTHGWASPNDPQRARTYYPGYHALIDAQNCRLELNGQKPVSRDDARKLITNYLTAYIEEGQIQNRNDIVTTLEEAGFTITRQGDNYITVTHDDLHQRIRLKGGIYSASWRLGAEFTAETRTEPKTGGSDCGAEFTTISDKLAAYLQKRRDFHRQKYGAHYPSSPDLVEMDGLFPGGDFACDLSGYLGRQLGDESIFNESVQTDSNEPTNPQPTQAEDLGGGTLSKQGGQVHHSTPQQPLPNRLEMQREALSQAVDNDPLNRLETLFKTVDNDLLEREQTLSKTVDNLPLARLESLSNPLDNLSLPRQETLSNPLDNTPLSRQEILSNSLDNDRWGKQEQALLNAVNEDDESTRKRITRNLQELCRELRGGQERTTEINHQFPRTTEQKIGVFNHSTERINQELLRNNQLLQQHTDRLIRENQQARERLSRHHERLRRIKEQQFRELDKFKTDINLADYAQTLGYEVNKKKSSVNCLVLKDNQGDKILVGINQADGHYFYSSVNDDRDKGSIIDFIQKRRNLNLGEVRKELRPWLNNPYSPKEATPKLTPITQDRQKILTEFEGFQVIVTHPYLTQRGITPETSNLPRFQGIIYMDSRNNLIFPHQDREGVCGYEIRHQAFKGFSSGGTKGLWCSQGASTDTKLVICESPLDCLSYHQLFPDETTRYMATGGTLSEKQKDLLQGALTKINDLGGEIIVATDKDEAGQKMAQELRNLAPSTAQMSRVVPTHHKDWNEALMAEIRRQREQEQEQQQKRSRGRGLSR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011727_1	1.1\|1087\|44\|NC_011727\|CRISPRCasFinder	1087-1130	44	NC_011727	Rippkaea orientalis PCC 8801 plasmid pP880103, complete sequence	1087-1130	0	1.0

1. spacer 1.1|1087|44|NC_011727|CRISPRCasFinder matches to NC_011727 (Rippkaea orientalis PCC 8801 plasmid pP880103, complete sequence) position: , mismatch: 0, identity: 1.0

aacttctcttttgtatacactctttagcgtgtcctgtccctagt	CRISPR spacer
aacttctcttttgtatacactctttagcgtgtcctgtccctagt	Protospacer
********************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

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CRISPR-Cas detection and classification

Crispr_ID: NC_011726_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_1

514094-514711

TypeI-D

V-U2

Consensus_repeat	Method
GTTTCAATCCC-----------ATTACTAGGATTCATTAAAAAGAAAC	PILER-CR
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	CRISPRCasFinder
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	CRT

8 spacers

cas2,cas1,cas4,cas6,csc1gr5,csc2gr7,cas10d,cas3,WYL

The CRISPR arrays of NC_011726_1

>merge|NC_011726|1|514094-514711|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAACTTATCGTATGTCCTCTATTCCTATCTTATCTTTTTAGTTTCAATCCCATTACTAGGATTCATTAAAAAGAAACACGCAAACAAAACCGGGAACACAATGGAATGCCGAGTTTCAATCCCATTACTAGGATTCATTAAAAAGAAACTAATGCTACTAATTCAAAGCTGACAGTAGAAGGCTCGTTTCAATCCCATTACTAGGATTCATTAAAAAGAAACCTGATTGTGATATGGTTGGTCAAATGATTAGCGAAGTTTCAATCCCATTACTAGGATTCATTAAAAAGAAACTCTTGATTGCTGAAACTCTCCCGTTAACTGGATATAAGTTTCAATCCCATTACTAGGATTCATTAAAAAGAAACCGTTCGACGGTAGGAATAAAGACTAAAACCGTGATGTTTCAATCCCATTACTAGGATTCATTAAAAAGAAACGATCATAACAATGGATTGGCTTTAGTTGAAGGACTGGTTTCAATCCCATTACTAGGATTCATTAAAAAGAAACGTTTATTCTATCCCCGTAACAGTTCCCCTCAAAAGGTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC

>NC_011726|1|1|514094-514711|PILER-CR
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	TTATCGTATGTCCTCTATTCCTATCTTATCTTTTTA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	ACGCAAACAAAACCGGGAACACAATGGAATGCCGA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	TAATGCTACTAATTCAAAGCTGACAGTAGAAGGCTC
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	CTGATTGTGATATGGTTGGTCAAATGATTAGCGAA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	TCTTGATTGCTGAAACTCTCCCGTTAACTGGATATAA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	CGTTCGACGGTAGGAATAAAGACTAAAACCGTGAT
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	GATCATAACAATGGATTGGCTTTAGTTGAAGGACTG
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	GTTTATTCTATCCCCGTAACAGTTCCCCTCAAAAG
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC

>NC_011726|1|1|514094-514711|CRISPRCasFinder
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	TTATCGTATGTCCTCTATTCCTATCTTATCTTTTTA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	ACGCAAACAAAACCGGGAACACAATGGAATGCCGA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	TAATGCTACTAATTCAAAGCTGACAGTAGAAGGCTC
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	CTGATTGTGATATGGTTGGTCAAATGATTAGCGAA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	TCTTGATTGCTGAAACTCTCCCGTTAACTGGATATAA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	CGTTCGACGGTAGGAATAAAGACTAAAACCGTGAT
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	GATCATAACAATGGATTGGCTTTAGTTGAAGGACTG
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	GTTTATTCTATCCCCGTAACAGTTCCCCTCAAAAG
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC

>NC_011726|1|1|514094-514711|CRT
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	TTATCGTATGTCCTCTATTCCTATCTTATCTTTTTA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	ACGCAAACAAAACCGGGAACACAATGGAATGCCGA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	TAATGCTACTAATTCAAAGCTGACAGTAGAAGGCTC
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	CTGATTGTGATATGGTTGGTCAAATGATTAGCGAA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	TCTTGATTGCTGAAACTCTCCCGTTAACTGGATATAA
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	CGTTCGACGGTAGGAATAAAGACTAAAACCGTGAT
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	GATCATAACAATGGATTGGCTTTAGTTGAAGGACTG
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC	GTTTATTCTATCCCCGTAACAGTTCCCCTCAAAAG
GTTTCAATCCCATTACTAGGATTCATTAAAAAGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_012593862.1\|503393_503789_+\|RidA-family-protein	unknown	unknown	gnl\|CDD\|129116
NC_011726.1\|WP_012593868.1\|507896_511217_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|273335
NC_011726.1\|WP_012593866.1\|506896_507448_+\|DUF3172-domain-containing-protein	unknown	unknown	gnl\|CDD\|371494
NC_011726.1\|WP_012593875.1\|517698_518475_-\|type-I-D-CRISPR-associated-protein-Cas5/Csc1	csc1gr5	cd09711_csc1gr5_CAS-I-D	gnl\|CDD\|274458
NC_011726.1\|WP_012593869.1\|511428_512085_+\|two-pore-domain-potassium-channel-family-protein	unknown	unknown	gnl\|CDD\|369572
NC_011726.1\|WP_012593864.1\|505197_505473_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012593867.1\|507463_507685_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012593863.1\|503855_505091_+\|LL-diaminopimelate-aminotransferase	unknown	unknown	gnl\|CDD\|181053
NC_011726.1\|WP_012593870.1\|513137_513950_+\|phytoene/squalene-synthase-family-protein	unknown	unknown	gnl\|CDD\|224478
NC_011726.1\|WP_012593865.1\|505883_506732_+\|prohibitin-family-protein	unknown	unknown	gnl\|CDD\|259799
NC_011726.1\|WP_012593877.1\|519760_522685_-\|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	cas10d	cd09712_cas10d_CAS-I-D	gnl\|CDD\|187843
NC_011726.1\|WP_012593871.1\|514904_515198_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_011726.1\|WP_012593878.1\|522742_524848_-\|type-I-D-CRISPR-associated-helicase-Cas3'	cas3	cd09710_cas3_CAS-I-D	gnl\|CDD\|187841
NC_011726.1\|WP_012593879.1\|524999_525248_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012593876.1\|518617_519688_-\|type-I-D-CRISPR-associated-protein-Cas7/Csc2	csc2gr7	cd09709_csc2gr7_CAS-I-D	gnl\|CDD\|375747
NC_011726.1\|WP_012593873.1\|516204_516795_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NC_011726.1\|WP_012593880.1\|525444_526392_+\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_011726.1\|WP_012593861.1\|501281_503363_+\|molecular-chaperone-DnaK	unknown	unknown	gnl\|CDD\|184039
NC_011726.1\|WP_012593874.1\|516920_517730_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl\|CDD\|337605
NC_011726.1\|WP_012593872.1\|515194_516172_-\|type-I-D-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|274976

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_012593862.1\|503393_503789_+\|RidA-family-protein	gnl\|CDD\|129116	TIGR00004, RutC_family_protein, reactive intermediate/imine deaminase. This protein was described initially as an inhibitor of protein synthesis intiation, then as an endoribonuclease active on single-stranded mRNA, endoribonuclease L-PSP. Members of this family, conserved in all domains of life and often with several members per bacterial genome, appear to catalyze a reaction that minimizes toxic by-products from reactions catalyzed by pyridoxal phosphate-dependent enzymes. [Cellular processes, Other].	7.82762e-61
NC_011726.1\|WP_012593868.1\|507896_511217_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NC_011726.1\|WP_012593866.1\|506896_507448_+\|DUF3172-domain-containing-protein	gnl\|CDD\|371494	pfam11371, DUF3172, Protein of unknown function (DUF3172). This family of proteins has no known function.	7.46272e-94
NC_011726.1\|WP_012593875.1\|517698_518475_-\|type-I-D-CRISPR-associated-protein-Cas5/Csc1	gnl\|CDD\|274458	TIGR03159, cas_Csc1, CRISPR type I-D/CYANO-associated protein Csc1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family is a CRISPR-associated (Cas) family strictly associated with the Cyano subtype of CRISPR/Cas locus, found in several species of Cyanobacteria and several archaeal species. This family is designated Csc1 for CRISPR/Cas Subtype Cyano protein 1, as it is often the first gene upstream of the core cas genes, cas3-cas4-cas1-cas2.	1.59599e-63
NC_011726.1\|WP_012593878.1\|522742_524848_-\|type-I-D-CRISPR-associated-helicase-Cas3'	gnl\|CDD\|187841	cd09710, Cas3_I-D, CRISPR/Cas system-associated protein Cas3; Distinct diverged subfamily of Cas3 helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Diverged DNA helicase Cas3'; signature gene for Type I and subtype I-D.	8.57797e-51
NC_011726.1\|WP_012593869.1\|511428_512085_+\|two-pore-domain-potassium-channel-family-protein	gnl\|CDD\|369572	pfam07885, Ion_trans_2, Ion channel. This family includes the two membrane helix type ion channels found in bacteria.	0.000186721
NC_011726.1\|WP_012593863.1\|503855_505091_+\|LL-diaminopimelate-aminotransferase	gnl\|CDD\|181053	PRK07590, PRK07590, L,L-diaminopimelate aminotransferase; Validated.	0
NC_011726.1\|WP_012593870.1\|513137_513950_+\|phytoene/squalene-synthase-family-protein	gnl\|CDD\|224478	COG1562, ERG9, Phytoene/squalene synthetase [Lipid metabolism].	1.3148e-52
NC_011726.1\|WP_012593865.1\|505883_506732_+\|prohibitin-family-protein	gnl\|CDD\|259799	cd03401, SPFH_prohibitin, Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model characterizes proteins similar to prohibitin (a lipid raft-associated integral membrane protein). Individual proteins of the SPFH (band 7) domain superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. These microdomains, in addition to being stable scaffolds, may also be dynamic units with their own regulatory functions. Prohibitin is a mitochondrial inner-membrane protein which may act as a chaperone for the stabilization of mitochondrial proteins. Human prohibitin forms a hetero-oligomeric complex with Bap-37 (prohibitin 2, an SPFH domain carrying homolog). This complex may protect non-assembled membrane proteins against proteolysis by the m-AAA protease. Prohibitin and Bap-37 yeast homologs have been implicated in yeast longevity and in the maintenance of mitochondrial morphology.	2.576e-60
NC_011726.1\|WP_012593877.1\|519760_522685_-\|type-I-D-CRISPR-associated-protein-Cas10d/Csc3	gnl\|CDD\|187843	cd09712, Cas10d_I-D, CRISPR/Cas system-associated protein Cas10d. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain. Fused to N-terminal HD domain; signature gene for I-D subtype; also known as Csc3 family.	0
NC_011726.1\|WP_012593871.1\|514904_515198_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.58058e-24
NC_011726.1\|WP_012593876.1\|518617_519688_-\|type-I-D-CRISPR-associated-protein-Cas7/Csc2	gnl\|CDD\|375747	pfam18320, Csc2, Csc2 Crispr. The Csc2 Crispr family of proteins forms a core RNA recognition motif-like domain, flanked by three peripheral insertion domains: a lid domain, a Zinc-binding domain and a helical domain. The CRISPR-Cas system is possibly a mechanism of defence against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	0
NC_011726.1\|WP_012593873.1\|516204_516795_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	3.47058e-32
NC_011726.1\|WP_012593880.1\|525444_526392_+\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	3.60845e-22
NC_011726.1\|WP_012593861.1\|501281_503363_+\|molecular-chaperone-DnaK	gnl\|CDD\|184039	PRK13411, PRK13411, molecular chaperone DnaK; Provisional.	0
NC_011726.1\|WP_012593874.1\|516920_517730_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	4.39112e-13
NC_011726.1\|WP_012593872.1\|515194_516172_-\|type-I-D-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274976	TIGR04093, hypothetical_protein_L8106_25395, CRISPR-associated endonuclease Cas1, subtype CYANO. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes a clade of Cas1 limited to the CYANO subtype of CRISPR/Cas system and most often the type found there.	1.08027e-150

>NC_011726.1|WP_012593870.1|513137_513950_+|phytoene/squalene-synthase-family-protein
MNLRNNALKILKETSRTFYIPISRLPDRLQEAVASAYLCMRAIDEVEDHPDLDNFTKAQLLRRMSLNLQAGSEKARVEDFSAGLMPYNACLPDVTLRVGEWALLAPDSIAPRIWDATAAMADRMAYWAENNWTIRTEAHLDQYTFSVAGAVGLLLSDLWAWYDGTQTNRSYAIGFGRGLQAVNIVRNHREDLRRGVNFLPQGWNEQDVHQYARRNLKLADLYTKSLPSGPALDFCKIPLALAYGTLEVMALGKEKLSRSDVIALVQRVTR
>NC_011726.1|WP_012593869.1|511428_512085_+|two-pore-domain-potassium-channel-family-protein
MKSTWQFYSHTTGYTRLFIDLIIVFLIAPLGNLSPIFQWLISLFFVMTLLLGVNTLAFPPKIIRTLQILAAISFAADIIVFPDFPKLTALTSLIAHVFQAIFVFCIMMAISFRITHEKQVNGAVIQGSICVYLLLGIFWFFLYQIVLFFDPFAFSIPEEITSNSLFYFSFTTLTTVGYGDVTPINPFAMTLSNAEALVGQIYPAIVIAKLVSLYERNE
>NC_011726.1|WP_012593868.1|507896_511217_-|efflux-RND-transporter-permease-subunit
MLLSFANAFIKRPVLSTVCTIVIILLGTIAMALLPLDKLPEIAPKKVAVSANYIGADAKTTEDNVTTVLEREINGTEQVRWIDSFTDNTGNVTVNVTFPTEMDRNTAQVLVQNRVSQAQSTLPSVVNQAGLRTNTQSPSLTLVYGFYVENGPDGQPLYDTTFIYNYVDRYIWNDMKGLPGVGSVALFGGANYAMRIWLDPDKLAARGLTALDVVGTINEQNFEVGIGRIGQQPAPQDQQFELPLRVAGRFTNVAEAEDMVVKVGEDGTLIRIKDVGYAELGMENYDTKVNVDGNPGVAFLIYQLPGSNALETADAAKAKMAELQQSFPPGLKVVIGLDNTLFVNASLEDLMITLLQAIALVVLVIFVFLQDWRTTVIPAIAIPVALVGAMIGLKAFGFTLNQLSLFACVLATGLVVDDGIVIVEAVSNKLSQGMRPRQAAMDAMDELFGATIATSVVLMAVFVPVTFFPGTTGIVYRQFALTIIFAVAFSTFNALTFSPTMSAILLSPPQPKHGPLALFFNWFNRGFDLVREGYRRFINFLTHVRILVMVVFIAGLVGTAWIYQTMPSGFIPAEDQGYFFGITEAPPGVSLNYTYAIDRQTTQIIQNMENADQVLDHVISLTGFSFEGRNANKSLTFVKLKPWGERPGPQKSAFGIIQKLNRAFAQQISGARVFAANAPPVDGLSSFDGSEIFIQDRQLKGIDALIENVQRVMAAANQRPEIGSTFTTFTFNSPLITMEIDRQKAKAQNIAIDDILRTLQTYIGSNFVNQFVFEGRLYRVYAQATPQDRANPEDIGRLYVRSRDGAIVQLSNLVTPTQTTYPPILTRYKTYPAIKLIISPAPGYSSGQVIQAMEEVANETLQPGFGYAWTNTAAEEKSSGGAAPVVFGLAFVMVFLVLAAQYESYIDPTIILLTVPLAILGALGAIWIRVSFVQTAPFNPGNGIWPILNNNMYAQVALVMLIGLAAKNAILIVEFANQARDLGMTITRSAIYAAEERLRPILMTAVSSLVGFAPLLTASSVGAVSRWSLGTAIFGGLALATVLSLVLVPILYIVVKNFEKYLLDGGKKPPSPPSSGNGHSKPSPPPEPQPENEEIAPVFKTSPQNE
>NC_011726.1|WP_012593867.1|507463_507685_-|hypothetical-protein
MNIRVIIFSAIMTALIGAMIGLALTKISQREQRRNILIIGGASVGFVIGAFQASIREQKRIRDEEFGDSDELQ
>NC_011726.1|WP_012593866.1|506896_507448_+|DUF3172-domain-containing-protein
MARRPPRDYPPRSNPPRYSSDSQLGSKINYGMIGLLAGIFVLGIGVGIGFSSTASFDPQNVASREVIDRSAPNAELCVQFGASAIVTDMRVFITLNPFSVFVTQPSMQPGCVLRRANIGLLEQQRLVTAEQLRDCKNRMNTFGFTGSLESKPNIACIYPNEAAGNLFLNPAGSVNPRSETDNF
>NC_011726.1|WP_012593865.1|505883_506732_+|prohibitin-family-protein
MNRQSAPSLQSLFGGIIAALLVVISFNSFVVINPGQAGVLSILGKAQDGALLEGIHFKPPLVSTVDIYDVTVQKFEVPAQSATKDLQDLTASFAINFRLDPLQVVDIRRTQGTLQNIVAKIIAPQTQESFKIAAAKRTVEQSITQRTELKQDFDDALNARLAKYGIIVLDTSVIDLTFSPEFARAVEEKQIAEQRAQRAVYIAQEAEQQAQADVNRAKGKAEAQRLLAETLKAQGGELVLQKEAIEAWREGGAKMPNVLVMGGESHGGGVPFLFNLSNVETQ
>NC_011726.1|WP_012593864.1|505197_505473_+|hypothetical-protein
MSISTFGKQLNIPEQYRQTVESFLYDNYITMLIEYVASLHNTGAISYNTCEYLIRELYSKTIEQMVERQIDQKLEKMAVKLNKKALSMSIV
>NC_011726.1|WP_012593863.1|503855_505091_+|LL-diaminopimelate-aminotransferase
MATINDNYLKLKAGYLFPEIARRVKTFAEANPDAKIIKLGIGDVTEPLPEACRTAMIKAIEDMGDRGTFKGYGPEQGYEWLREKIATHDFQARNCDVDASEIFVSDGAKCDTGNILDIFGKNNKIAVTDPVYPVYVDTNVMAGHTGEVNDKGEYEGLVYLPINAENNFIAEIPSQKVDIIYLCFPNNPTGATATKDYLKNWVDYAKANGSIIFFDAAYEAFITDSSLPHSIYEIEGARDCAIEFRSFSKNAGFTGTRCALTVVPKTLTAKASDGSDVELWKLWNRRQSTKFNGVSYIVQRGAEAVYSEAGKAQVQALISFYLENAQIICDKLKGAGFEVYGGVNAPYIWLKTPHNLSSWDFFDKLLQTANVVGTPGSGFGAAGEGYFRISAFNSRENVLEAMKRITSQFHL
>NC_011726.1|WP_012593862.1|503393_503789_+|RidA-family-protein
MTNHRIIRTEQAPAPVGPYNQAIAATGQLLFVAGQIPLNPETGEIVGTGDIIAQTRQVMANLEAILKAAGTKWDKVVKTTVFLTDLGNFSSMNQVYAQYFSEEIAPARACVEVSRLPKDVLVEIDCIAVID
>NC_011726.1|WP_012593861.1|501281_503363_+|molecular-chaperone-DnaK
MGKVIGIDLGTTNSCVAVLEGGKPIVIPNSEGGRTTPSIVGFSKGQQRLVGQLAKRQAVTNAENTVYSIKRFIGRRWDETREERSRVPYECVKGRDDTVNVDIRGQHYSPQEISAMILQKLKADAESYLGEPVTEAVITVPAYFTDAQRQATKDAGTIAGLDVLRIINEPTAAALAYGLDKQDQEQFILVFDLGGGTFDVSILQLGDGVFEVKATAGNNHLGGDDFDHAVVQWMVKNFKDQESIDLSQDKMAIQRLREAAEKAKIELSNMLSTSINLPFITSDESGPKHLEAELSRALFEDLTKNLTLSTQEPLKQALKDCGLDPKFIERVILVGGSTRMPAIHRIIQEVFPASQLDRSINPDEAVALGAAIQGGVLGGEVEDLLLLDVTPLSLGIETLGEVFTKIIERNTTIPSSKSQVFSTATDGQTSVEIHVLQGERAMAKDNRSLGKCLLAGIPPAPRGIPQIEVSFEIDVNGILKVSAQDQGTGKEQSIIISHTGGLKPNEIERMQQEAQEYAEEDRRRMQTIELQNQADSLFYTYKTTLEENGDLIRQELKFQSKQRKEQLESALQDPDLSLETLKSYLEQFQQIILLIGTEVYQQGKPYQKSSMFSSMMGEEILTDLNLVMESLETTSMGTSSFVGESLETQTFERTQDYQQTAPMYTHVENEDEDEGFFDFDDDETVASDYEAVD
>NC_011726.1|WP_012593871.1|514904_515198_-|CRISPR-associated-endonuclease-Cas2
MNTLFYLIIYDLPATKAGNKRRKRLYEMLCGYGNWTQLSVFECFLTAVQFANLQSKLENLIQPNEDSVRIYILDAGSVRKTLTYGSEKPRQVDTLIL
>NC_011726.1|WP_012593872.1|515194_516172_-|type-I-D-CRISPR-associated-endonuclease-Cas1
MSILYLTQPDAVLSKKQEAFHVALKQEDGSWKKQLIPAQTVEQIVLIGYPSITGEALCYALELGIPVHYLSCFGKYLGSALPGYSRNGQLRLAQYHVHDNEEQRLALVKTVVTGKIHNQYHVLYRYQQKDNPLKEHKQLVKSKTTLEQVRGVEGLAAKDYFNVFKLILDSQWNFNGRNRRPPTDPVNALLSFAYGLLRVQVTAAVHIAGLDPYIGYLHETTRGQPAMVLDLMEEFRPLIADSLVLSVISHKEIKPTDFNESLGAYLLSDSGRKTFLQAFERKLNTEFKHPVFGYQCSYRRSIELQARLFSRYLQENIPYKSLSLR
>NC_011726.1|WP_012593873.1|516204_516795_-|CRISPR-associated-protein-Cas4
MIDNYLPLAYLNAFEYCTRRFYWEYVLGEMANNEHIIIGRHLHRNINQEGIIKEEDTIIHRQQWVWSDRLQIKGIIDAVEEKESSLVPVEYKKGRMSQHLNDHFQLCAAALCLEEKTGKIITYGEIFYHANRRRQRVDFSDRLRCSTEQAIHHTHELVNQKMPSPINNSKKCRDCSLKTMCLPKEVKQLRNSLISD
>NC_011726.1|WP_012593874.1|516920_517730_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MVQDILPQLHKYQLQSLVIELGVAKQGKLPATLSRAIHACVLNWLSLADSQLANQIHDSQISPLCLSGLIGNRRQPYSLLGDYFLLRIGVLQPSLIKPLLKGIEAQETQTLELGKFPFIIRQVYSMPQSHKLSQLTDYYSLALYSPTMTEIQLKFLSPTSFKQIQGVQPFPLPELVFNSLLRKWNHFAPQELKFPEIQWQSFVSAFELKTHALKMEGGAEIGSQGWVKYCFKDTEQARIASILSHFAFYAGVGRKTTMGMGQTQLLVNT
>NC_011726.1|WP_012593875.1|517698_518475_-|type-I-D-CRISPR-associated-protein-Cas5/Csc1
MNIYYCQLTLHDNIFFATREMGLLYETEKYLHNWALSYAFFKGTYIPHPYRLQGKSAQKPNYLDSTGEQSLAHLNRLKIYVFPAKPLRWSYQINTFKAAQTTYYGKSQQFGDKGANRNYPINYGRAKELAVGSEYHTFLISSQELNIPHWIRVGKWSAKVEVKPYLIPQKAISQHSGTYLCDHPLNPIDLPFNQELLLYNRIVMPPVSLVSQAQLQGNYSKINKNNWNDCPSDLTDLPQQICLPLGVNYGAGYIASAS
>NC_011726.1|WP_012593876.1|518617_519688_-|type-I-D-CRISPR-associated-protein-Cas7/Csc2
MSILETLKPQFQSAFPRLASANYVHFIMLRHSQSFPVFQTDGVLNTVRTQAGLMAKDSLSRLVMFKRKQTTPERLTGRELLRSLNITTADKNDKEKGCEYNGEGSCKKCPDCIIYGFAIGDSGSERSKVYSDSTFSLSAYEQSHRTFTFNAPFEGGTMSEQGVMRSAINELDHILPEITFPNIETLRDSTYEGFIYVLGNILRTKRYGAQESRTGTMKNHLVGIAFCDGEIFSNLRFTQALYDGLEGDVNQPIDEICHQASQIVQTLLSDEPVRKIKTIFGEELNHLINEVSGIYQNDTLLTETLNMLYQQTKTYSENHGSLAKSKPPKAEGNKSKGRTKKKGDDEQTSLDLNIAE
>NC_011726.1|WP_012593877.1|519760_522685_-|type-I-D-CRISPR-associated-protein-Cas10d/Csc3
MTLLQILLLETISQDTDPILISYLETVLPAMEPEFALIPALGGSQQIHYQNLIAIGNRYAQENAKRFSDKADQNLLVHVLNALLTAWNLVDHLTKPLSDIEKYLLCLGLTLHDYNKYCLGHGEESPKVSNINEIINICQELGKKLNFQAFWSDWEQYLPEIVYLAQNTQFKAGTNAIPANYPLFTLADSRRLDLPLRRLLAFGDIAVHLQDPADIISKTGGDRLREHLRFLGIKKALVYHRLRDTLGILSNGIHNATLRFAKDLNWQPLLFFAQGVIYLAPIDYTSPEKMELQGFIWQEISQLLASSMLKGEIGFKRDGKGLKVAPQTLELFTPVQLIRNLADVINVKVANAKVPATPKRLEKLELTEIERQLLEKGADLRADRIAELIILAQREFLADSPEFIDWTLQFWGLEKQITAEQTQEQSGGVNYGWYRVAANYIANHFTLSLEDVSGKLVDFCQQLADWATSNQLLSSHSSSTFEVFNSYLEQYLEIQGWQSSTPNLSQELSTYIMAKTQSSKQPICSLSSGEFISEDQMDSVVLFKPQQYSNKNPLGGGKIKRGISKIWALEMLLRQALWTVPSGKFEDQQPVFLYIFPAYVYSPQIAAAIRSLVNDMKRVNLWDVRKHWLHEDMNLDSLRSLQWRKEEAEVGRFKDKYSRADIPFMGTVYTTTRGKTLTEAWIDPAFLTLALPILLGVKVIATSSSVPLYNSDNDFLDSVILDAPAGFWQLLKLSTSLRIQELSVALKRLLTIYTIHLDNRSNPPDARWQALNSTVREVITDVLNVFSIADEKLREDQREASPQEVQRYWKFAEIFAQGDTIMTEKLKLTKELVRQYRTFYQVKWSESSHTILLPLTKALEEILSTPEHWDDEELILQGAGILNDALDRQEVYKRPLLQDKSIPYEIRKQQELQAIHQFMTTCVKELFGQMCKGDRALLQEYRNRIKSGAESAYKLLAFEEKSNSSQQQKSSEDQ
>NC_011726.1|WP_012593878.1|522742_524848_-|type-I-D-CRISPR-associated-helicase-Cas3'
MKINLKPLYSKLNAGVGNCPLGCQEMCRVQQQAPQFKAPSGCNCPLYQHQAESYPYLTKGDTDIIFITAPTAGGKSLLASLPSLLDPNFRMMGLYPTIELVEDQTEQQNNYHNLFGLNSEERIDKLFGVELTQRIKEFNSNRFQQLWLAIETKEVILTNPDIFHLMTHFRYRDNAYGTDELPLALAKFPDLWVFDEFHIFGAHQETAVLNSMMLIRRTQQQKKRFLFTSATVKTDFVEQLKQTGLKIKEIAGEYKSEAQQGYRQILQAVELSIINLKEEDGFSWLINNAAKIRKILKAEDKGRGLIILNSVVMVRRISQELQSLLPEIVVREISGRIDRKERSQTQQLLQEEEKPVLVVATSAVDVGVDFRIHLLITESSDSATVIQRLGRLGRHSGFSNYQAFLLLSGRTPWVINRLQEKLESKQDVTREELIEAIQYAFDPPKEYQEYRNRWGAIQVQGMFSQMMGSNAKVMQSIKERMSEDLKRVYGNKLENKAWYAMGHNCLGKAIQSELLRFRGGSTLQAAVWDEQRFYTYDLLRLLPYATVDILDRETFLKAATKAGHIEEAFPSQYLQVYLRIEQWLDKRLNLNLFCNRESDELLVGKLFLITRLKLDGHPQSDVISCLSRCNLLTFLVPVDRSRTQSHWEVSYCLHLNPLFGLYRLKDASEQAYACAFNQDALLLEALNWKLTKFYRERSLIF
>NC_011726.1|WP_012593879.1|524999_525248_-|hypothetical-protein
MTNSNKKMLLFQAGTQGWKNPQPNNAIISKRIQPKLTTKELIDLTKIPPHKLPRIGGYLTWKGYFIIHSAKNLWQVCQPLAA
>NC_011726.1|WP_012593880.1|525444_526392_+|WYL-domain-containing-protein
MSSNYNQIAFALEILKLLAEKPRFRQELGDLLTQHLEKQGKSSGDVLQKLTRTIAKLRDCGFEIKSAPNCPYELIESNFPLILSSQQKQALYLATYVLSNMGFSAEAERLGRLYDFLGDEHPHQLHFDFSPPVDYSGEKIRQIIQQLEQRIEQQCRYTIYYQNSRGESRLWDLDRSELRFHNGVLYLFSFVPDWKSYHFPKSPNIEQNILFHINRIQSVLGVSNTRWFYDFPTIKIRYCMTGALANYQPRRSTEQVIEQNLDEKFIIIETIEDCLFWFRQRLLQYGANAQVLEPIWLREQIRDELKKSYENYTQQ

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Crispr_ID: NC_011726_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_2

604771-604971

TypeV

I-D,II-B

Consensus_repeat	Method
GTTTCAATCCCTCATAGGGATTATTGCTTATTTTAACTGATAAAGAAT	PILER-CR
GTTTCAATCCCTCATAGGGATTATTGCTTATTTTAACT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_011726_2

>merge|NC_011726|2|604771-604971|PILER-CR,CRISPRCasFinder
GTTTCAATCCCTCATAGGGATTATTGCTTATTTTAACTTATAAGGAATTGCAGCATAGGCAGCCGAAAATTCAGGGTTTCAATCCCTCATAGGGATTATTGCTTATTTTAACTGGGAATGATCATAATAATAAATAACCTGAGACTCAGAAATGTTTCAATCCCTCATAGGGATTATTGCTTATTTTAACTGCTATAGTCT

>NC_011726|2|2|604771-604971|PILER-CR
GTTTCAATCCCTCATAGGGATTATTGCTTATTTTAACTTATAAGGAAT	TGCAGCATAGGCAGCCGAAAATTCAGG
GTTTCAATCCCTCATAGGGATTATTGCTTATTTTAACTGGGAATGATC	ATAATAATAAATAACCTGAGACTCAGAAATGTTTCAATC
CCTCATAGGGATTATTGCTTATTTTAACTGCTATAGTCT

>NC_011726|2|2|604771-604961|CRISPRCasFinder
GTTTCAATCCCTCATAGGGATTATTGCTTATTTTAACT	TATAAGGAATTGCAGCATAGGCAGCCGAAAATTCAGG
GTTTCAATCCCTCATAGGGATTATTGCTTATTTTAACT	GGGAATGATCATAATAATAAATAACCTGAGACTCAGAAAT
GTTTCAATCCCTCATAGGGATTATTGCTTATTTTAACT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_012593933.1\|595554_597213_-\|toll/interleukin-1-receptor-domain-containing-protein	unknown	unknown	gnl\|CDD\|379328
NC_011726.1\|WP_012593935.1\|598556_600224_+\|cytochrome-c-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|213748
NC_011726.1\|WP_012593940.1\|605270_606443_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	unknown	unknown	gnl\|CDD\|235674
NC_011726.1\|WP_015783194.1\|602294_602444_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366774
NC_011726.1\|WP_012593947.1\|611653_611821_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237653
NC_011726.1\|WP_012593948.1\|611804_612596_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_011726.1\|WP_012593932.1\|591711_595506_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238121
NC_011726.1\|WP_012593936.1\|600322_600940_+\|heme-copper-oxidase-subunit-III	unknown	unknown	gnl\|CDD\|224758
NC_011726.1\|WP_012593937.1\|601206_602298_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012593939.1\|604072_604720_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223092
NC_011726.1\|WP_012593942.1\|607218_607794_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374761
NC_011726.1\|WP_012593949.1\|612623_613106_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012593945.1\|610168_610681_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379237
NC_011726.1\|WP_012593946.1\|610726_611590_-\|inositol-monophosphatase-family-protein	unknown	unknown	gnl\|CDD\|238815
NC_011726.1\|WP_012593934.1\|597565_598528_+\|cytochrome-c-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224537
NC_011726.1\|WP_012593943.1\|608120_608345_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012593931.1\|591216_591687_+\|DUF1816-domain-containing-protein	unknown	unknown	gnl\|CDD\|370151
NC_011726.1\|WP_012593944.1\|608434_610030_+\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173813
NC_011726.1\|WP_012593938.1\|602526_604005_-\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NC_011726.1\|WP_012593941.1\|606447_606954_-\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_012593933.1\|595554_597213_-\|toll/interleukin-1-receptor-domain-containing-protein	gnl\|CDD\|379328	pfam13676, TIR_2, TIR domain. This is a family of bacterial Toll-like receptors.	3.25588e-14
NC_011726.1\|WP_012593935.1\|598556_600224_+\|cytochrome-c-oxidase-subunit-I	gnl\|CDD\|213748	TIGR02891, Probable_cytochrome_c_oxidase_subunit_1-beta, cytochrome c oxidase, subunit I. This large family represents subunit I's (CtaD, CoxA, CaaA) of cytochrome c oxidases of bacterial origin. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits I-III form the functional core of the enzyme complex. Subunit I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit II and heme a of subunit I to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer. In the bacilli an apparent split (paralogism) has created a sister clade (TIGR02882) encoding subunits (QoxA) of the aa3-type quinone oxidase complex which reacts directly with quinones, bypassing the interaction with soluble cytochrome c. This model attempts to exclude these sequences, placing them between the trusted and noise cutoffs. These families, as well as archaeal and eukaryotic cytochrome c subunit I's are included within the superfamily model, pfam00115. [Energy metabolism, Electron transport].	0
NC_011726.1\|WP_012593940.1\|605270_606443_-\|5-(carboxyamino)imidazole-ribonucleotide-synthase	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	0
NC_011726.1\|WP_015783194.1\|602294_602444_-\|hypothetical-protein	gnl\|CDD\|366774	pfam01724, DUF29, Domain of unknown function DUF29. This family consists of various hypothetical proteins from cyanobacteria, none of which are functionally described. The aligned region is approximately 120-140 amino acids long corresponding to almost the entire length of the proteins in the family. Structure 3fcn is a small protein that has a novel all-alpha fold. The N-terminal helical hairpin is likely to function as a dimerization module. This protein is a member of PFam family PF01724. The function of this protein is unknown. One protein sequence contains a fusion of this protein and a DnaB domain, suggesting a possible role in DNA helicase activity (hypothetical). Dali hits have low Z and high rmsd, suggesting probably only topological similarities (not functional relevance) (details derived from TOPSAN). The family has several highly conserved sequence motifs, including YD/ExD, DxxNVxEEIE, and CPY/F/W, as well as conserved tryptophans.	1.48603e-06
NC_011726.1\|WP_012593947.1\|611653_611821_+\|hypothetical-protein	gnl\|CDD\|237653	PRK14276, PRK14276, chaperone protein DnaJ; Provisional.	0.000996554
NC_011726.1\|WP_012593948.1\|611804_612596_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.24853e-19
NC_011726.1\|WP_012593932.1\|591711_595506_-\|hypothetical-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	9.44497e-71
NC_011726.1\|WP_012593936.1\|600322_600940_+\|heme-copper-oxidase-subunit-III	gnl\|CDD\|224758	COG1845, CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 [Energy production and conversion].	4.44811e-64
NC_011726.1\|WP_012593938.1\|602526_604005_-\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NC_011726.1\|WP_012593939.1\|604072_604720_+\|hypothetical-protein	gnl\|CDD\|223092	COG0013, AlaS, Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	0.00148407
NC_011726.1\|WP_012593942.1\|607218_607794_+\|hypothetical-protein	gnl\|CDD\|374761	pfam16734, Pilin_GH, Type IV pilin-like G and H, putative. Pilin_GH is a family from Cyanobacteria. All the proteins are putatively annotated as being general secretion pathway proteins G and H, and are likely to be pilins of the type IV secretory pathway.	6.76609e-12
NC_011726.1\|WP_012593945.1\|610168_610681_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379237	pfam13523, Acetyltransf_8, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.31268e-09
NC_011726.1\|WP_012593946.1\|610726_611590_-\|inositol-monophosphatase-family-protein	gnl\|CDD\|238815	cd01637, IMPase_like, Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1,6-bisphosphate, inositol poly- and monophosphates, PAP and PAPS, sedoheptulose-1,7-bisphosphate and probably others.	9.68408e-28
NC_011726.1\|WP_012593934.1\|597565_598528_+\|cytochrome-c-oxidase-subunit-II	gnl\|CDD\|224537	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion].	1.7617e-72
NC_011726.1\|WP_012593931.1\|591216_591687_+\|DUF1816-domain-containing-protein	gnl\|CDD\|370151	pfam08846, DUF1816, Domain of unknown function (DUF1816). Crocosphaera watsonii CpcD is associated with the pfam01383 domain suggesting this presumed domain could have a role in phycobilisomes.	2.17076e-35
NC_011726.1\|WP_012593944.1\|608434_610030_+\|S8-family-serine-peptidase	gnl\|CDD\|173813	cd07488, Peptidases_S8_2, Peptidase S8 family domain, uncharacterized subfamily 2. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	5.22971e-64
NC_011726.1\|WP_012593941.1\|606447_606954_-\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	9.41794e-15

>NC_011726.1|WP_012593939.1|604072_604720_+|hypothetical-protein
MSELLDLPLVQELANIRLNNLDALPDCSAVYLVADDANRVYYVGQSSHLQLSLKNCDRFEDFLAVASKLCWLVCDEAELVEIESDYINYYNPPLNNNIDIENIKKNTIASGMTPEQQLERYLEICTIIKELEKEKEELKQNIVAFVSDYKQQYDTNLQYKGVTFLVSERKSWEYSPTVKELEEKVKKLKKQEEKEGIATISKVSVYPIVRGELTL
>NC_011726.1|WP_012593938.1|602526_604005_-|signal-recognition-particle-protein
MFDALAERLEDAWKKLRGQDKITENNIQDALTEVRRALLAADVNLQVVKNFIADVEKAALGAEVISGVNPGQQFIKIVYDELVKVMGESNVPLATTATAPTVILMAGLQGTGKTTATAKLALYLRKQKRSCLMVATDIYRPAAIDQLITLGQQIEVPVFELGSEANPVDIARQGVEKAKELGVDTVLIDTAGRLQIDESMMVELARIKEAVKPDDTLLVVDAMTGQEAANLTRTFHEQIGITGAILTKMDGDTRGGAALSVRQISGQPIKFIGVGEKVEALQPFYPDRMASRILNMGDILSLVEKAQEEIDIADVEKMQSKILEAKFDFNDFLKQMRLMKNMGSLGGLLKMIPGLNKLSSTDIEKGEKELKRTEAMINSMTVEERKNPDLLAKSPSRRRRIAKGSGHAESEVSKLVTNFTRMRSMMQQMGQGGMPAMPGMGGGMPGMGGGMPGMGGMFGGGMGGQVPPGFRGQAGSQKKKKKGKKKKGFGTL
>NC_011726.1|WP_015783194.1|602294_602444_-|hypothetical-protein
MTLSTAKTIKTLYEQDYNLWLETTVKQLELGQFLIISFAVTLNNHNYSH
>NC_011726.1|WP_012593937.1|601206_602298_+|hypothetical-protein
MIFVTPLQWIKKKLRKRVNHQSSISVVNNKLNQELENDLSISVVDQVDQVLDNQASIAIVDNFDQKSNNQSCISALNNINIRVVGDRYSGKTVYMASLAYWPNVNSESPLQSVTSFGDQETSQELFNCAQNILKEGLKLNPKNIDDFCVDQIKDYGLKISLKNYFSEKLSQNRSDFIEFTINCKDYSGEFFRDVIYKSNDPFLKDYLEDFQLADGLLLLVDGTSYRKDQQYAKGLEKFLLYLNQTKLHNPKRRIAFVLNKCELSELWMSRHQPRELVAKRFPQMMATLENWSDQGLGEVEYFTASAFGTLGNDYYQPNTKILAQAHQGTFYMIRHLEKWRPFGLVSPIYWLCTGERHEALDQD
>NC_011726.1|WP_012593936.1|600322_600940_+|heme-copper-oxidase-subunit-III
MQGSAIQESEVTINLHSTGGGHHGGHPDHRLFGIALFLIAESALFLGLFGAFLIYRTVMPVWPPEGTPELELLLPGVNTIILVSSSFVMHKGQAAIKKNDVSGLKLWFAITAVMGIIFLCGQMYEYFHLEMGLTTNLFASCFYALTGFHGLHVTFGLLLILAVLWRSRKEGHYTSESFFGVEAAELYWHFVDVVWIILFILVYLL
>NC_011726.1|WP_012593935.1|598556_600224_+|cytochrome-c-oxidase-subunit-I
MTTVVESSHTAHKERKWTDYFTFSTDHKVIGIQYLVTSFAFYFIGGAFAEVIRTELATADPDFISPELYNQFMTIHGTIMIFLWIVPAGAAFANYLIPLMVGAEDMAFPRLNAVAFWLTPPGGIMLLASFFVSGGAAQSGWTSYPPLSLVSGVWGEEIWILSVLLVGTSSILGAINFVTTIFKMRIPDMDLHSMPLFCWAMLATSALILLSTPVLAAALVLLSFDLIAGTAFFNPTGGGDPVVYQHMFWFYSHPAVYIMILPFFGVISEVLPVHARKPIFGYRAIAYSSLAISFLGLIVWAHHMFTSGTPGWLRIFFMAATMLIAVPTGIKIFSWCATLWGGKLNLNTAMLFGVGFIATFLMGGLTGVMLSSVPFDIHVHDTYFVVGHFHYVLFGGAAMGLFAGFYHWFPKMTGRMINEPLGKMHFALLFIGLNITFLPMHKLGLMGMNRRIALYDVQFEPINLICTIGAYILALSSLPFIINIFWSLVKGEKASRNPWRAYTLEWQTASPPIIENFEEEPVLWAGPYDYGTDLESVNEEETVEDMLAEVGSQSK
>NC_011726.1|WP_012593934.1|597565_598528_+|cytochrome-c-oxidase-subunit-II
MKIPSNIITLLVGIVITLISLWYGQNHGLMPVAASYDATQVDGIFNFMMTIATGLFLLVEGVLVFCLIKFRRRPGDQTDGPPIEGNVPLEILWTAIPTVIVFILALYSFEVYNNMGGLDPIISRDTPPQQIAMDSHNSDIALGIGTSVDETSGISPLIVDVQGMQYAWIFTYPETGIVAGELHVPKNRPVQLRIAATDVLHAFWVPQLRLKQDAIPGRDAMLAFTANLEGNYPIVCAELCGAYHGGMKSTLFVEDEETYAQWVEANKPVQEANLGETVAVNPKNLSDGQFLSPYAQEMGITADSLAQVQPKAHHSHLGHF
>NC_011726.1|WP_012593933.1|595554_597213_-|toll/interleukin-1-receptor-domain-containing-protein
MDTSVLSRIVKSQIHRVVKGIADGKVVFFLGDEINLCGRHKTEEGPLETWRSPDNQAIYAPTNTELALHLDQIFNCKYSIEVIRCPLLPHDIPLDFPDGCPVETDLPEQCPVKTGGIKKMALQQVSQYIDIDDTLDPYGTLPDILWELFDAEYPPNHLHQFLANLPQLIIAKGYPHPYPLIVTACLDNTLERAFKQAQQPFDLVSFVQDRQGSRFVHQKFRSQLKSGNCPQIFATTEPIDIDKPNEYAEDLSLNTYPIILKLYGAIGCGENFVITENNCLDYLAHRDIKSLLPSSLLKQLLNNYILFLGYSPSYWNQRVILHRIWQEEIFSPSSKTWWVIQFKPDLLDRKFWKRYCGQEPINILLDDYVTELEAQIEDLPETSMVKNPNNSPKKSNLYHRDKVFISYSHKDKDWLEKLQTMLMPVIQLGKVSIWDDTQIKPGSNWKQDIENALASAKVAVLLVSQNFLASDFIATEELPPLLEAAEKEGVKILWVYLNYCQYKYTALKNLQATHNITEPLQALSPPEQDKILYEISDEIIEAIQPEDSKLIA
>NC_011726.1|WP_012593932.1|591711_595506_-|hypothetical-protein
MFSLPLIPQLTPIKQRLLKEKPVVYSSAIETSPYKGLMPYCEADAPYFFGRKKWTRIITDNLMSSRLTVVYGTSGVGKSSLLRAGVAYQFKQWIQKNLREFGYPEFAVIVFNAWRDDPVAALLQKVEETITQIIPKVQVPDPNNSLTDTLENWANVLISEEQRSGKLFIILDQFEEYFLYHGYEKGEKTFADQFSQAVNQTGLPVNFIIAIRENALAKLDFFKGSIPHLFTNYLRIPYLDEQAAVDAIRQPIRVFNQHRKLDQHKASHLRTLTLLKGSKTLGLALLWVMMLQERFSQAAIAIETELVQTIIEQVTVGQVYLGNTGRGMIDPKTVTSTQKVIETPYLQLVMTRLWEEDILKRGGNRLQLSTLMELGGAENIVKQHLSERMSRLSRKERNIAAQVFQYLVTPGGTKIAYPILQLAKDIEVTSEELQTLLDKLCQPQQYILRSVGPSPNEPDVERYEIFHDTLAPAILDWRQKYQQRQERNKWRKRTVAASAIALMMTGLFGIAEYQRLQAKVSEIKAIIAHADSLIIANRAFDALVEDLSAYKKFKQTEQDLSIKLLQVIVPRVSAKKQQLKQDIQRLLELGLVSINERNRLIVSEQKVLDVTFSHDGKWLATTSKDGQIKLWDLQGKLIQSLSEDNSEKSYFWRTSFSPDDQLLAAASTSGKINLWSLKDNQIKKLKSLVGHQGWIFDVKFHPTQPILASVSSDGTIKLWRFNGEEFQDKPIESVDVSEINQKNRTNEKPVIRTLRFSPDGKILATATDNGKTSNDPGIITLWIFKDNKLKLLTAFPEKHNDWIWDINFSHDGKMLATASRDGTVKLWNLEGQELKSMGEHNVPFTGVNFAIYGQKKEIIVIGASHDKTIKFWNLEGKELTTLKGHQSAIWRAIFSSDGKTLASASEDGTVKLWTLNDQDILGHKGRISQVSFNPDGQTLATAAEDHTVKLWRFDGKNTDNLQYLKTIQAHTNEVRSVDFSPDGSLLATASFDKTAKLWNWNLETDKPLSTFNKHTAELWKVEFNPKLSILGTVSNDGTAKLWKFDGTMHRNFNNFLQEDPDKVISLSFSPDGQKLATARWVRVNSKKIDVMLWDVNGLEKPIQKFPSLQTNWLKDIDFSADGSMIATSSKDGTVKLWSLNGEDQTPYQNNYPKINHNNSTISSVSFSPIQPLLLTASDDQTVKLWTIDGKLQQTFFGHQGAVLSATFSPNGQFIASSGSDGKVILWKRDLTLEELLQKTCNWLGGYLENNPDVEPQNKSLCQDQ
>NC_011726.1|WP_012593931.1|591216_591687_+|DUF1816-domain-containing-protein
MATNNDANSRFFLYEVAIQPQSGGFNKIKGLIYQEGKIFLKVPYGRMKQEMKRIQRLGGKIVNITPITEISSLKESLDLIEPEIEEISVVSLGLPWWVEISTTHPNCLYYFGPFDSAEEALSYQDGYVEDLREEGAQNITLYIKQCQPQVLTQEWD
>NC_011726.1|WP_012593940.1|605270_606443_-|5-(carboxyamino)imidazole-ribonucleotide-synthase
MDGMTIKRVGVIGGGQLAWMMDEAAQQLGIDLVIQTPSQDDPAVSIAAEVIFAPIADATATAQLATRCDVITFENEFIDLEALQKLEAKGVCFRPSLGVLAALLDKYEQRCYLKQIGVPVPQCATLDSSSTPEFSFPLVLKTRRHGYDGQGTFIIQSLDELDSIFRRLEGVSLMIEEFVPFERELAVMASRSVTGEIIVYPVVETYQQNQVCHWVIAPAAVSEAIKAEIEQIARHLLTQLGVVGIFGIELFLTSQGQVLVNEIAPRTHNSGHYTLDACETSQFEMQLRAVAGLPLGSPKLKALGTVMVNLLGYEQSHHDYKQKREQLAAIPGVHVHWYGKTESRPGRKLGHVTVLLGEINDSLTDEMLREQLLGTVKKIESIWYESDSRE
>NC_011726.1|WP_012593941.1|606447_606954_-|pentapeptide-repeat-containing-protein
MKYLVRLILILLCCVFLSSPLSALAASSASVTAGVSSFEDIKLVGQDFSRQDLKEVKFANADLTEANFSDSDLRGAVFNGVELKQANFHGANLTNGLAYLSSFRDADLSDAILSEVIMLRTVFDNANITGADFTLAVLDGEEVAKLCQRADGVNSKTGMSTRESLGCL
>NC_011726.1|WP_012593942.1|607218_607794_+|hypothetical-protein
MKRKDESSQTNSAKELPIWQMLLLIFLRYIIGGIVGLFGLMFVLLMVVGFGPPGEQRNHRPHPKILLGAINRAQQGYYTEHKQFASTWDDLGIRRPSTKDFEYHFFAILDGKLTGVVIAKGIDNKKIESRDYIAGVNYNRKYKIFNTIVCRASDQLKSQNYQITNPEQAISNYGVVDQSTMICGEGLMEIK
>NC_011726.1|WP_012593943.1|608120_608345_+|hypothetical-protein
MVYYWNLVRPRFPNIQVRLQQIETFSASPSVALGPAMWLSCSLEDKCREKRLYCSQLYGHDLSLDLCTDCLDSQ
>NC_011726.1|WP_012593944.1|608434_610030_+|S8-family-serine-peptidase
MNKSITWLAGSLSVFGIIVPTLALDNSIGEAGINAHRLHEQPHNLTGRKIAIGQVEIGRPGQFGLDKVAAWNPSFRLAGVYFRNKNVTANGNLDNHAAMVATVMVSRDKRIPGVAPDARLYSAAVGALKQGGQPEECLASQHIAQQNSGDVRAINFSFGESLQQDPRENAKLDGNALLTQCIDWSARVHDVLYVIAGNQGKGGIPIPTDHYNGITTAYTAKRQGQFSKVDFANLSALPQGIGRRLIKREINVGTRRSISLVAPGNKIALYDLSGKISEVSGTSFAAPHITASVALLQEFGDRQLKTKQPNWSLDSRRHQVMKAVLLNSADKLTDQGDGLLLGMVRTVLSKRNQTWLESDAYQDPQIPLDIEMGTGHLNAFRAYQQFSAGQWKPDSGVPSLGWNYETISYQKQHDYVIENPLPKGSYVSITLVWDRHVELKDTNNNDQYDIGETFSDRGLNNLDLYLLSATDQTTTKSTCSSVSKVDSTEHIFCQVPATGLYKIRVDYPQLIHQQTQPYGLAWWTFSPETNP
>NC_011726.1|WP_012593945.1|610168_610681_+|GNAT-family-N-acetyltransferase
MSKQIKQVDLVPFCQEEDSDRIQFWLNTAHVKKWWINPDNHFKNILNHPSSDHGIIIADGIKVGYLRWQKVDMLELASVGITTIPEGSIDIDIFIGEKDYIGCGIGSRILKQLVNQLAQDTTIPLIGMATSVDNFIAIKAYQKVGFRCLFQFDSPTYGRCWILALNPQES
>NC_011726.1|WP_012593946.1|610726_611590_-|inositol-monophosphatase-family-protein
MVLAPQPGLILKTLLPHLKVAAAYARQLQSKITALPAKLESDNFLGAALTDADISIQNLVEVVLLGTFPQIRFYGEEYQKSANTKYFRATDFGEFGDYLVTLDPIDGTQFYLDGHQNYQIILSVLNTDDYEAVITLSPAINHYCYALRGQGVFEGTFEVEFENCKPLQKIPSKAAILLGWGMEKLKPFLINKYPVIDIATSYSKQRQIPNVNGLLGGELSGAIIRSGNLIDSAALAFMAKEAGYLVTLFDGSPVPPLNTCKNYKLPGLLIACNSSIHQDLLTAVKQI
>NC_011726.1|WP_012593947.1|611653_611821_+|hypothetical-protein
MNHQSSTLKTSNLICHHCEGKGYSVIRDCTGEIQREETCLFCCGTGKKQDDEPED
>NC_011726.1|WP_012593948.1|611804_612596_+|tetratricopeptide-repeat-protein
MNRKINLSNFLLFLSLTLGYFLFLGCSTNSSQPIPKTSEIPITKNQKPLETPALTTTAEDRKNAANLRQLGLQYRQQENYPKAIESLEKSVSLDSKNLSGLVLLGWTLHLAGKSPSAQQTLEHALTINSQHIETLNALGIVYLVQGNLEQAIATHSKAVIINPNNEIAHYNLNLAYQRLQQYTKAIKHGQQAIKLEPHNPHPWVALAITYWEMGDSKKSQETYRQAVNLDSRYRQVDFLSHLKKAGFSQEQIKQTQKVLESLF
>NC_011726.1|WP_012593949.1|612623_613106_+|hypothetical-protein
MKVNYYLTIVGLLISILIWDFLNFKKLTAKETINLVPTEITRVNLTTSEQSYPAKARFWGLVANGVNQVSTVTLNSNSNQRLLVTIILPENCRRVFEITETKITKVIHDCPSQKIDESSQYAEWVAFHNATTREVQMIAPPIKVENPLYIRKQAFWLIQY

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Crispr_ID: NC_011726_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_3

827835-827932

Orphan

Consensus_repeat	Method
GTTGAGGAAGAAGAAGACATTGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011726_3

>merge|NC_011726|3|827835-827932|CRISPRCasFinder
GTTGAGGAAGAAGAAGACATTGAGTCCCCAGAACTCAACCTTGAGGAAGAAGAGATTGAACCTTCAGAACCCTCTGTTAAGGAAGAAGAAGACATTGA

>NC_011726|3|3|827835-827932|CRISPRCasFinder
GTTGAGGAAGAAGAAGACATTGA	GTCCCCAGAACTCAACCTTGAGGAAGAAGAGATTGAACCTTCAGAACCCTCT
GTTAAGGAAGAAGAAGACATTGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_012594154.1\|831048_831642_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227672
NC_011726.1\|WP_012594148.1\|824915_825290_-\|DUF5331-domain-containing-protein	unknown	unknown	gnl\|CDD\|375088
NC_011726.1\|WP_162013504.1\|826936_827056_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224913
NC_011726.1\|WP_012594151.1\|827105_827303_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012594156.1\|832127_832973_-\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|223810
NC_011726.1\|WP_012594153.1\|828511_830965_+\|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl\|CDD\|225118
NC_011726.1\|WP_012594144.1\|819956_821021_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375541
NC_011726.1\|WP_012594162.1\|837471_838413_+\|UPF0104-family-protein	unknown	unknown	gnl\|CDD\|223469
NC_011726.1\|WP_012594149.1\|825451_826321_-\|ferredoxin:protochlorophyllide-reductase-(ATP-dependent)-iron-sulfur-ATP-binding-protein	unknown	unknown	gnl\|CDD\|177011
NC_011726.1\|WP_012594147.1\|823510_824911_-\|ferredoxin:protochlorophyllide-reductase-(ATP-dependent)-subunit-N	unknown	unknown	gnl\|CDD\|214353
NC_011726.1\|WP_012594160.1\|836131_836662_+\|translation-initiation-factor-IF-3	unknown	unknown	gnl\|CDD\|234582
NC_011726.1\|WP_012594146.1\|822525_823236_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012594161.1\|836998_837475_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012594143.1\|818922_819735_-\|carbon-dioxide-concentrating-mechanism-protein	unknown	unknown	gnl\|CDD\|226943
NC_011726.1\|WP_012594155.1\|831701_832055_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227726
NC_011726.1\|WP_012594157.1\|832978_834277_-\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
NC_011726.1\|WP_012594142.1\|818357_818861_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012594159.1\|835021_835939_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|215315
NC_011726.1\|WP_012594145.1\|821330_822308_+\|quinolinate-synthase-NadA	unknown	unknown	gnl\|CDD\|236489
NC_011726.1\|WP_012594158.1\|834513_835002_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_012594148.1\|824915_825290_-\|DUF5331-domain-containing-protein	gnl\|CDD\|375088	pfam17265, DUF5331, Family of unknown function (DUF5331). This bacterial family of unknown function can be found in Cyanobacteria.	6.69299e-62
NC_011726.1\|WP_162013504.1\|826936_827056_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|224913	COG2002, AbrB, Regulators of stationary/sporulation gene expression [Transcription].	3.37057e-05
NC_011726.1\|WP_012594149.1\|825451_826321_-\|ferredoxin:protochlorophyllide-reductase-(ATP-dependent)-iron-sulfur-ATP-binding-protein	gnl\|CDD\|177011	CHL00072, chlL, photochlorophyllide reductase subunit L.	0
NC_011726.1\|WP_012594154.1\|831048_831642_+\|hypothetical-protein	gnl\|CDD\|227672	COG5381, COG5381, Uncharacterized protein conserved in bacteria [Function unknown].	3.24788e-29
NC_011726.1\|WP_012594144.1\|819956_821021_+\|hypothetical-protein	gnl\|CDD\|375541	pfam18087, RuBisCo_chap_C, Rubisco Assembly chaperone C-terminal domain. This is the C-terminal domain, also known as the beta domain, of Rubsico Assembly Chaperone protein (Raf1). Raf1 is necessary for rubisco to catalyze the rate-limiting step of carbon fixation through carboxylating the five-carbon sugar substrate ribulose-1,5-bisphosphate. The beta domains primary function is dimerization, which is critical for Raf1 to achieve the necessary avidity for complex formation with RbcL (the large complex sub-unbit of Rubsico) assembly intermediates. The beta domain is also involved, to a small extent, in binding to RbcL with use of the lustiness near the beta domain's conserved top surface.	1.21153e-65
NC_011726.1\|WP_012594162.1\|837471_838413_+\|UPF0104-family-protein	gnl\|CDD\|223469	COG0392, COG0392, Predicted integral membrane protein [Function unknown].	3.61196e-31
NC_011726.1\|WP_012594153.1\|828511_830965_+\|SpoIIE-family-protein-phosphatase	gnl\|CDD\|225118	COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription].	7.25584e-59
NC_011726.1\|WP_012594147.1\|823510_824911_-\|ferredoxin:protochlorophyllide-reductase-(ATP-dependent)-subunit-N	gnl\|CDD\|214353	CHL00073, chlN, photochlorophyllide reductase subunit N.	0
NC_011726.1\|WP_012594160.1\|836131_836662_+\|translation-initiation-factor-IF-3	gnl\|CDD\|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	3.57982e-91
NC_011726.1\|WP_012594143.1\|818922_819735_-\|carbon-dioxide-concentrating-mechanism-protein	gnl\|CDD\|226943	COG4577, CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion].	1.14311e-48
NC_011726.1\|WP_012594155.1\|831701_832055_+\|hypothetical-protein	gnl\|CDD\|227726	COG5439, COG5439, Uncharacterized conserved protein [Function unknown].	6.47339e-31
NC_011726.1\|WP_012594157.1\|832978_834277_-\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NC_011726.1\|WP_012594156.1\|832127_832973_-\|M23-family-metallopeptidase	gnl\|CDD\|223810	COG0739, NlpD, Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane].	3.54389e-37
NC_011726.1\|WP_012594159.1\|835021_835939_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|215315	PLN02578, PLN02578, hydrolase.	2.50398e-64
NC_011726.1\|WP_012594145.1\|821330_822308_+\|quinolinate-synthase-NadA	gnl\|CDD\|236489	PRK09375, PRK09375, quinolinate synthase NadA.	0

>NC_011726.1|WP_012594151.1|827105_827303_+|hypothetical-protein
MSKSTRFLLSSFAIPFIISLVITLTVYILRGMRILGFLPGGVVLILIAVSIILGILYTRQATRRF
>NC_011726.1|WP_162013504.1|826936_827056_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MTEKGTTTKITDGGRIVIPPEYRPALSFNIGDDVIFVGT
>NC_011726.1|WP_012594149.1|825451_826321_-|ferredoxin:protochlorophyllide-reductase-(ATP-dependent)-iron-sulfur-ATP-binding-protein
MTLTLAVYGKGGIGKSTTSCNISTALAKRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLQEKDFHYEDIWPEDVIYKGYAGVDCVEAGGPPAGAGCGGYVVGETVKLLKELNAFDEYDVILFDVLGDVVCGGFAAPLNYADYCLIVTDNGFDALFAANRIAASVREKARTHPLRLAGLIGNRTSKRDLIDKYIEAVPMPVLEILPLIEDIRVSRVKGKTLFEMTESDPSLDYVCNYYLNIADQLLAMPEGVVPNDAPDRELFTLLSDFYLNPQTPVKSQEEELDLMMV
>NC_011726.1|WP_012594148.1|824915_825290_-|DUF5331-domain-containing-protein
MITFEEIKATLPDKWLLYYTTNHSWIKPLMDNRKWWHKTPDDGKRPCADIILGAITALEPQLSFWMPPFCKLNSDGNKLIEVLGLNFDPEKELKKRSEQSSKLSIKSDDQFMRQIREQNKQGED
>NC_011726.1|WP_012594147.1|823510_824911_-|ferredoxin:protochlorophyllide-reductase-(ATP-dependent)-subunit-N
MTALQEPTALQFECETGNYHTFCPISCVAWLYQKIEDSFFLVIGTKTCGYFLQNAMGVMIFAEPRYAMAELEEGDISAQLNDYEELKRLCLQIKRDRNPSVIVWIGTCTTEIIKMDLEGLAPKLESEIGIPIVTARANGLDYAFTQGEDTVLAAMAHKCPQSVKAEEEKEERNAIHKLLNFGRKKEDIKQEESEYVDHPPLVLFGSLPDPVVTNLTLELKKQGVKISGWLPSKRYTELPVIDEGYFVSGVNPFLSRTATTLMRRRKCKLIGAPFPIGPDGTRAWIEKICSVFGIQPQGLEEREAKIWESLEDYLQLIRGKSVFFMGDNLLEVSLARFLIRCGMTCHEIGIPYMDKRYQQAELAFLEKTCQEMGVPIPKIVEKPDNYNQIQRIYELKPDLVITGMAHANPLEARGINTKWSVEFTFAQIHGFTNARDILELATRPLRRNNNLKELGWEKLVREEANV
>NC_011726.1|WP_012594146.1|822525_823236_+|hypothetical-protein
MKVIKYLSITQLIVYLLLNFIIANNDSASAQSPAYNNLTLDIQQKLETDIDKTIELTYRSVKITDQQKAIKVFLEVTLRKLSGGFGYNYSQTPLIKVMIEQNNNLRVVTRNFGLETNHYNFDLFPLAFSPNNRYLLIAGGAMATDYTFHKIVDLGNNDTTINMNLCPIETYEGFVSNIEIVFSCSDFGMGEDFIAILNLQDKTVTKKRKGSLKQINLLPRSYIFTDQPKVIKIQKF
>NC_011726.1|WP_012594145.1|821330_822308_+|quinolinate-synthase-NadA
MFTTVRPQSTLTPPTANLIPNDLFTAINELKKDLNAVILAHYYQDPDIQDIADFIGDSLALSQQAASTNAEVIVFAGVHFMAETAKILNPDKLVLLPDLNAGCSLADSCPPEAFAQFKAQYPGCLVVSYINCTAEIKAMSDIICTSSNAVKIVNQLPKDRPIIFAPDRNLGRYVMEQTRRELILWQGSCMVHETFSEKKIVQLKIEYPEAEIIAHPECEPSVLRHANYIGSTTALLNYSQQSASQIFIVATEPGIIHQMEKETPHKRFIPAPAINNCACNECPHMRLNTLEKLYLAMKFKQPEITMDETIRLAALRPIQRMLEMS
>NC_011726.1|WP_012594144.1|819956_821021_+|hypothetical-protein
MNEHPQLSPEQANQLLRSLLEKQGSWVDWGQACYQLQQAGYNGQSIFEQTGFQSSQQNLIIVASQVYESLVNTGVAEEVLSYYRGPKSDVLYELRILNQDQRAIVAELAKEKTLEATEAKEVAKTFQAFNRLSQVPEAFTNHPGDAMAHQCWKQARQKKDLQDRTRLIAKGLKFAHSATARSAIEKLLMDFTVVPARSAPLLPLYRLEQESDISRIIAVVGSLPLSQNDLNRVENLVGVDPFNVVSYSGTGSLVSLPGWQAILKADDPVAILCSSDRLPKSIPGPTETVLVVVDRSLQNWDVNSYFLVEENEELMFKWFEEDPNTTLLGQIIIVVRPKKIFDENNILEPWQMDD
>NC_011726.1|WP_012594143.1|818922_819735_-|carbon-dioxide-concentrating-mechanism-protein
MTRLAASSQRRATQPDMKSSRLPSDSALGLVSTHSFPAIVGTADMMLKSSDVTLVGYEKIGSGHCTAVVRGKVANVRLAVEEGAKTAEQFGQLISKLVIPRPMPNLEAIFPIGSRLVELAQQKQGYSRLSNRSIGLLETRGFPAMVGAADAMLKSADVQLASYEIIGDGLCTAIIRGSVANVAVAIEAGIQEAEKIGELHAVMIIPRLLEDLEHTLPVANCWIEQPEALPMLMPKTVKERQRELIALPELEKKPLAFKKAVEIDQTELLE
>NC_011726.1|WP_012594142.1|818357_818861_+|hypothetical-protein
MSQAIEIPNLDILAQELAAIQQTGSKRIALLGSRHVPITHQQLIEMMSYALVLGGNRLMTSGATGTNAAAIKGAMRADPNLLTVILPQSLERQPRESREQLQQVVHLVENPENDSLSLGEASALCNREIISRCQQLICFAFHDSHTLLQTCAEAEEQRKLVTLFYFD
>NC_011726.1|WP_012594153.1|828511_830965_+|SpoIIE-family-protein-phosphatase
MNHWRILLTKKWANLSLRAKIILAFFSLMIVSTTTVTVFSYRVLRIELTAQVGKDLQKQATKLAQQVSNLLINQVDQVTLISLSNVFQNELNLINSRYPKNQNTIQQEIQKNSQIWHQSKKSNRLLGNYLNNPISRELREYQKHFPNNYQIFVTDKYGAIAGTTNLNLEYNQGEKQWWQQTWNNGRGAVYIEEPQYNQENLLLLVNIAVPIYKRSNSQASEVIGIIHTSYKISHALLPLLQNINSGKTGHAYLFVSPKKYFSDYKFVNETNQELTKFISSLASYKEIKYQGEKRFFSKASVQPKNQEFSLLNNLPWLIIIYQDSSEILHPLIIARQTIMMAALGTLLVAGILASFIERLISTPIRVLTKITQRIASGDLDYEIDLEQKDEIGLLAANFNIMVESLKSYFSKLRTSLKELSDMKFALDQSVLVTVMEPNGRITYVNDKFCEISQYSRQELIGNNYRFLKSRYHTPEFYQSIWDTLNQGNIWRGEIKNQTKDGSYYWVDSTMVPFLDENNKPFQYLAIRYDITARKDFEEALSQKVKERTDQLAQANQEIIQLNHQLQGENLRMSAQLNVARQLQQMVLPKPEELAAIKGLELAGFMEPADEVGGDYYDVLATDDVVTISIGDVTGHGLESGILMIMTQTVVRTLKEIREHDPVKFLDTLNRTLYRNIERMNSDRHLTLAVLNYSHRRVSLSGQHEEVIFVRAGGELQRIDTMNLGFPIGLDQNITDFIDQISLELQTGDGLVLYTDGITEAKDINKNHYGIERLCQVIQQNWEKSAQQIQELVIQDLHEHIGQQKIFDDITLFVLKQK
>NC_011726.1|WP_012594154.1|831048_831642_+|hypothetical-protein
MTKTFGSYILNFPHTNNSLELIFNPTSSSIKKIWRNNRLSAHFIADYFSNFLPIDENNPAYKQRVKNSKGAVSYVANELLENTMKFSDPNSDHDIKIGVHFLNNSEFTVTVFATNAMAAQDIDKFQYFIQELLSCEPDEFYVRQIEKSLSEEEEEESSGLGLVTMMMDYSAKLGWKFETCPKDPKIVLVTTMVQIVL
>NC_011726.1|WP_012594155.1|831701_832055_+|hypothetical-protein
MSVQEIAGDDYTIKYDPEAVIVNFYGELALGGPKDYQPITDFLNEIADSEPQKITLDVRELNFLNSSGISMLSKFVISFRRKENINLTVLGSNEVPWQGKSLSNLKKLLPSLELITD
>NC_011726.1|WP_012594156.1|832127_832973_-|M23-family-metallopeptidase
MSSELLLVLFVSLVPPLVNLAQTPPSSLCPAPILSRLERHRVVTGETLASIAQAYNLFPETLIQLNPSLKGGAVQVGQEIVIPPFNGIRVEVPKGASWQDLATAYGLRADVLFELNGCVKTPKVVFIPGVNWQTSQGTRKNDYTGLKGYPLQAPAQVGLAYGWHTNQTTGQSFFHGGIDLLAEPGTPVLAADAGEVIFASQEGTYGFLVVVDHGNSRQTRYAHLSRFQAKIGQSVRQGDIIGYVGTTGRPDIPQSHLHFEVRYRFPVGWVAQDPTTHLPSP
>NC_011726.1|WP_012594157.1|832978_834277_-|homoserine-dehydrogenase
MVVKIGLLGLGTVGTGTAQILLDPSGRNPLLKDITIHRVGVRSPDKPRSVQFPPEVITSDLKAIVNDPDIDIVVELLGGLEPARSLILQAIAQKKHVVTANKAVIARYGDEIYNSANQAGVYVLLEAAVGGGIPIIKPLKQSLGANRITQIIGIINGTTNYILSEMTTAGADFSDVLAEAQRLGYAEADPTADVDGLDAADKIAILASLGFGGRVQREDVYCEGIRQVSAADIAYADKLGFVIKLLAIAKGSGGQESQTLELRVHPTLVPKDHPLASINGVYNAILVAGDPLGQVMFYGPGAGSGPTASAVVSDIMNIVAILKSSGQTPTLDPLLSCVHQHFCQITPIEGIKSRFYARFLTGDLPGVIGHLGMSFGNHQVSLESVVQIGFQGELAEIVVVTHNVGEGNFRAALAEIRTLEAIKSIPSILRVL
>NC_011726.1|WP_012594158.1|834513_835002_+|hypothetical-protein
MKKLTQIFLVLGGIVGFILLSGSPALGQPDSSCYMINQSGQVMDLSAICHKGVSWSTTESNQTAPASEFRSYSQVQNYDNTSQDWETDLPSRYQGYSLYSTRFPDDGSGIGQRIYSRVENRPSIVTYSHKTWEPGYDPSTPEGQQAQYDLTIRTLRVLDYFR
>NC_011726.1|WP_012594159.1|835021_835939_-|alpha/beta-fold-hydrolase
MLDQQPWEKRIGRQRDWIWQGWQIRYSYLHCPIKSISQQKPPLILLHGFGAAIEHWRHNIPILAEKHSVYALDLLGFGGSQKAAADYSAYLWAQQVYDFWRTFIRQPVILVGNSIGSLVCLTVAATYPEMVAGIAMLSLPDVSLRQEMMPRWLQPIVTSLESLLSPPFLIKGLLTIVRRPSIIRPWVTLAYCDRSAITDELVEIISLPAYDQGAARTLCLLVEGARNPKFAPSAKAILPNLTIPMLLIWGKQDRFIPPSLAPMFAQLNSRITLVELDQVGHCPQDESPDRFNPILLDWIDSKVII
>NC_011726.1|WP_012594160.1|836131_836662_+|translation-initiation-factor-IF-3
MIDKRRPQRDLPKINERIRFPEIRVIDSDGSQVGVITPKEALSLAQEKELDLVLVSETAKPPVCRIMDYGKYKFEQEKKAREAKKKQHTADVKEVKMRYKIGESDYNVRVNQAKRFLKSGDKVKATVTFRGREIQHANLAQELLERMAKDLEELAEIQQAPKREGRNMMMFLTPKK
>NC_011726.1|WP_012594161.1|836998_837475_+|hypothetical-protein
MKNFRLLLKLLGLSCLLILTNTMVKAESEINSSLLSELEKNRQLWRSQAITDYQFIYQQQCFCPPPANTPLKVLIDQNNISQVLNLKTGQPLGTSQFNQVKSIEQLFTILEEAIKQNADEISVTYDPQLGYPTKIAIDYKKIMADEEQGYLIKDLQKL
>NC_011726.1|WP_012594162.1|837471_838413_+|UPF0104-family-protein
MSKSSFIRSVSKVLPIALAVLLLSVSIKTIIHEFKDHSWQSIWQYLQTISNTRKMASVALTGLGYLAMTGYDILGFQYINQVLERTKIAGTAFISYAVGNTIGFSAFSGTAIRYHFYSSWGVSKLKIAQLIVFTHLTFWLGLFGVSGVVFLVDPLTLPKVLKLPFNSVHPIGFIFLALVAIYFVIGYFWKSSLRIGSEEIVFPSPEMSLQLIALAAVDWGLACGVLYLLLPLDHSMSYPGFFGIYILALTAGLMSTVPGGLGVFDTVILLLRPDSISAPDILGALIAYRIIYYILPLIIALGLFIIQHFQKHK

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Crispr_ID: NC_011726_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_4

911959-913021

TypeI-A,TypeV

V-U2

Consensus_repeat	Method
GTTTCAATCCC-----------ATTACTAGGATTCATTAATAAGAAAC	PILER-CR
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	CRISPRCasFinder
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	CRT

14 spacers

csa3

The CRISPR arrays of NC_011726_4

>merge|NC_011726|4|911959-913021|PILER-CR,CRISPRCasFinder,CRT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACCCGTTGGTTGCTTCTTCTAAGGGATCAATGGTTAGGGGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACTCGATCATCCCCTGAATTGATTTGACGCGGTTAATTTGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACCTAAGCCAAAAAGGGACGGATTTAGAGGAATATTGGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACTCGTCGCCTGAATATCCCAGGGCTTTGATAGTTAAAGTGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACGGTTAGCTTGAAACTGAGCGGTTATTTTTAATAAGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACTTTTGTATGCTTCTGCCTTTAATCCTAGGGTTTTAAGTTGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACATCGTGACTTTTTCAGGCTTTTCATCTTTATCCTTGGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACTCCAACTTTTTAAAAAATAGCTTGACAATTTGATTGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACACTTTATGATTCCTTTACTTTAGATCATGTTGGTATTTCGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACTCGTTCTTTCCAATGGGTCCGTAGCACTTCCCGCCGGGGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACTTGTTTTGTCTTCTCGTCGTCGTCGTCGTTCTTCCGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACTTTAAATGCTAAGCGATCGCATAGTTTTTTGTGCGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACAATTCTTGCAAACAAACAGTTAATTTTTTTACTGTCTGTTTCTTATTAATGAATCCTAGTAATGGGATTGAAACTTTAATAAGTTTAAAACCCTATCAAGCCTTAAACGTTTCTTATTAATGAATCCTAGTAATGGGATTGGAAT

>NC_011726|4|3|911959-912950|PILER-CR
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	CCGTTGGTTGCTTCTTCTAAGGGATCAATGGTTAGGG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCGATCATCCCCTGAATTGATTTGACGCGGTTAATTT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	CTAAGCCAAAAAGGGACGGATTTAGAGGAATATTG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCGTCGCCTGAATATCCCAGGGCTTTGATAGTTAAAGT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	GGTTAGCTTGAAACTGAGCGGTTATTTTTAATAA
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTTTGTATGCTTCTGCCTTTAATCCTAGGGTTTTAAGTT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	ATCGTGACTTTTTCAGGCTTTTCATCTTTATCCTTG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCCAACTTTTTAAAAAATAGCTTGACAATTTGATT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	ACTTTATGATTCCTTTACTTTAGATCATGTTGGTATTTC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCGTTCTTTCCAATGGGTCCGTAGCACTTCCCGCCGGG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTGTTTTGTCTTCTCGTCGTCGTCGTCGTTCTTCC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTTAAATGCTAAGCGATCGCATAGTTTTTTGTGC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	AATTCTTGCAAACAAACAGTTAATTTTTTTACTGTCT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC

>NC_011726|4|4|911959-913021|CRISPRCasFinder
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	CCGTTGGTTGCTTCTTCTAAGGGATCAATGGTTAGGG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCGATCATCCCCTGAATTGATTTGACGCGGTTAATTT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	CTAAGCCAAAAAGGGACGGATTTAGAGGAATATTG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCGTCGCCTGAATATCCCAGGGCTTTGATAGTTAAAGT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	GGTTAGCTTGAAACTGAGCGGTTATTTTTAATAA
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTTTGTATGCTTCTGCCTTTAATCCTAGGGTTTTAAGTT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	ATCGTGACTTTTTCAGGCTTTTCATCTTTATCCTTG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCCAACTTTTTAAAAAATAGCTTGACAATTTGATT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	ACTTTATGATTCCTTTACTTTAGATCATGTTGGTATTTC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCGTTCTTTCCAATGGGTCCGTAGCACTTCCCGCCGGG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTGTTTTGTCTTCTCGTCGTCGTCGTCGTTCTTCC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTTAAATGCTAAGCGATCGCATAGTTTTTTGTGC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	AATTCTTGCAAACAAACAGTTAATTTTTTTACTGTCT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTTAATAAGTTTAAAACCCTATCAAGCCTTAAAC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGGAAT

>NC_011726|4|2|911959-913021|CRT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	CCGTTGGTTGCTTCTTCTAAGGGATCAATGGTTAGGG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCGATCATCCCCTGAATTGATTTGACGCGGTTAATTT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	CTAAGCCAAAAAGGGACGGATTTAGAGGAATATTG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCGTCGCCTGAATATCCCAGGGCTTTGATAGTTAAAGT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	GGTTAGCTTGAAACTGAGCGGTTATTTTTAATAA
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTTTGTATGCTTCTGCCTTTAATCCTAGGGTTTTAAGTT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	ATCGTGACTTTTTCAGGCTTTTCATCTTTATCCTTG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCCAACTTTTTAAAAAATAGCTTGACAATTTGATT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	ACTTTATGATTCCTTTACTTTAGATCATGTTGGTATTTC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TCGTTCTTTCCAATGGGTCCGTAGCACTTCCCGCCGGG
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTGTTTTGTCTTCTCGTCGTCGTCGTCGTTCTTCC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTTAAATGCTAAGCGATCGCATAGTTTTTTGTGC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	AATTCTTGCAAACAAACAGTTAATTTTTTTACTGTCT
GTTTCTTATTAATGAATCCTAGTAATGGGATTGAAAC	TTTAATAAGTTTAAAACCCTATCAAGCCTTAAAC
GTTTCTTATTAATGAATCCTAGTAATGGGATTGGAAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_012594229.1\|919796_920156_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238786
NC_011726.1\|WP_012594226.1\|916312_917488_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012594219.1\|907047_908157_-\|hydrogenase-formation-protein-HypD	unknown	unknown	gnl\|CDD\|237892
NC_011726.1\|WP_012594218.1\|905880_906921_+\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NC_011726.1\|WP_012594223.1\|913239_913749_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|366663
NC_011726.1\|WP_012594213.1\|902306_902696_+\|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|197713
NC_011726.1\|WP_012594227.1\|917833_918520_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012594216.1\|903992_905069_+\|WD40-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|225201
NC_011726.1\|WP_012594215.1\|903033_904005_+\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NC_011726.1\|WP_012594232.1\|922699_922975_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012594214.1\|902692_902866_-\|metallothionein	unknown	unknown	gnl\|CDD\|366903
NC_011726.1\|WP_012594224.1\|913945_914827_-\|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase	unknown	unknown	gnl\|CDD\|224938
NC_011726.1\|WP_012594225.1\|915002_916025_-\|long-chain-acyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl\|CDD\|184944
NC_011726.1\|WP_012594230.1\|920332_922018_+\|DUF3352-domain-containing-protein	unknown	unknown	gnl\|CDD\|371750
NC_011726.1\|WP_012594231.1\|922055_922496_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012594217.1\|905166_905811_+\|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl\|CDD\|236472
NC_011726.1\|WP_012594222.1\|909864_911712_+\|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|213023
NC_011726.1\|WP_012594228.1\|918549_919632_-\|heat-inducible-transcriptional-repressor-HrcA	unknown	unknown	gnl\|CDD\|234621
NC_011726.1\|WP_012594221.1\|908815_909517_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012594220.1\|908345_908786_+\|SufE-family-protein	unknown	unknown	gnl\|CDD\|376883

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_012594229.1\|919796_920156_-\|hypothetical-protein	gnl\|CDD\|238786	cd01528, RHOD_2, Member of the Rhodanese Homology Domain superfamily, subgroup 2. Subgroup 2 includes uncharacterized putative rhodanese-related domains.	9.23708e-41
NC_011726.1\|WP_012594219.1\|907047_908157_-\|hydrogenase-formation-protein-HypD	gnl\|CDD\|237892	PRK15062, PRK15062, hydrogenase isoenzymes formation protein HypD; Provisional.	0
NC_011726.1\|WP_012594218.1\|905880_906921_+\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	2.94246e-111
NC_011726.1\|WP_012594223.1\|913239_913749_-\|transcriptional-repressor	gnl\|CDD\|366663	pfam01475, FUR, Ferric uptake regulator family. This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes. This family is also known as the FUR family.	1.46475e-47
NC_011726.1\|WP_012594213.1\|902306_902696_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	3.87329e-20
NC_011726.1\|WP_012594216.1\|903992_905069_+\|WD40-repeat-domain-containing-protein	gnl\|CDD\|225201	COG2319, COG2319, FOG: WD40 repeat [General function prediction only].	4.47962e-27
NC_011726.1\|WP_012594215.1\|903033_904005_+\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	6.13166e-129
NC_011726.1\|WP_012594214.1\|902692_902866_-\|metallothionein	gnl\|CDD\|366903	pfam02069, Metallothio_Pro, Prokaryotic metallothionein.	4.23327e-18
NC_011726.1\|WP_012594224.1\|913945_914827_-\|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase	gnl\|CDD\|224938	COG2027, DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane].	1.03181e-50
NC_011726.1\|WP_012594225.1\|915002_916025_-\|long-chain-acyl-[acyl-carrier-protein]-reductase	gnl\|CDD\|184944	PRK14982, PRK14982, acyl-ACP reductase; Provisional.	0
NC_011726.1\|WP_012594217.1\|905166_905811_+\|GTP-cyclohydrolase-I-FolE	gnl\|CDD\|236472	PRK09347, folE, GTP cyclohydrolase I; Provisional.	7.49459e-122
NC_011726.1\|WP_012594222.1\|909864_911712_+\|polysaccharide-deacetylase-family-protein	gnl\|CDD\|213023	cd10918, CE4_NodB_like_5s_6s, Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, hemin storage system HmsF protein in gram-negative species, intercellular adhesion proteins IcaB, and many uncharacterized prokaryotic polysaccharide deacetylases. It also includes a putative polysaccharide deacetylase YxkH encoded by the Bacillus subtilis yxkH gene, which is one of six polysaccharide deacetylase gene homologs present in the Bacillus subtilis genome. Sequence comparison shows all family members contain a conserved domain similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, which consists of a deformed (beta/alpha)8 barrel fold with 6 or 7 strands. However, in this family, most proteins have 5 strands and some have 6 strands. Moreover, long insertions are found in many family members, whose function remains unknown.	4.06672e-44
NC_011726.1\|WP_012594228.1\|918549_919632_-\|heat-inducible-transcriptional-repressor-HrcA	gnl\|CDD\|234621	PRK00082, hrcA, heat-inducible transcription repressor; Provisional.	1.29214e-134
NC_011726.1\|WP_012594230.1\|920332_922018_+\|DUF3352-domain-containing-protein	gnl\|CDD\|371750	pfam11832, DUF3352, Protein of unknown function (DUF3352). This family of proteins are functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 538 to 575 amino acids in length.	3.12074e-173
NC_011726.1\|WP_012594220.1\|908345_908786_+\|SufE-family-protein	gnl\|CDD\|376883	pfam02657, SufE, Fe-S metabolism associated domain. This family consists of the SufE-related proteins. These have been implicated in Fe-S metabolism and export).	4.24121e-59

>NC_011726.1|WP_012594222.1|909864_911712_+|polysaccharide-deacetylase-family-protein
MSSSLVQWWSLKRVILCSSSLLISGYGILAVKSIKFDQTTQAIASTSNPNSNTSDCQSPTSNLSSSSQWLSVSAPKTLNQSSPLTPIDCITAVLPFEQGSTNRKIIISPKTFPDLWNAAKNTLNQLPKPFPTIHEQARIAKVPILMYHDILPKKEVFFDVTPQELEAHFKLIQAQGITPISVDLLLEHLQKGVPLPDKPVLLTFDDAYGGHYHYVYPLLKKYGYPAVFSVYIKKMDGKTKRTSLTWEQLKEMSIDPLVTIASHTISHPRDLRLLSDDQLFQEIIISKKILEEKLGIAIRYFTYPEGKLDPRVKQWVMSGGYEMAFSMDDNKEIFAGDSPDLLTIGRFGQSQIQQVINQAWGGYPTAKLPDEFDFLAPIRKFDHQIEGTNLIIISGGKPSTIHADSRYQVPEIIKGTEAIAAVDGAFFSLEYLDSNVMIGPVMSQGKTFIPGNKSENPLLNGRPLVLISDQWVRFIPFDANRHNTLNGIQTEFEDGELITDVFVAAAWLVKNSQPQPRENFGNLFDFDVPRHRAFWGIHQSGQPMIGVSKDPVDSVKLGRILQKLGFREAVMLDSGASTSLAYHGESLVAYIPRPVPHVVTLLPQWELLVSQQERD
>NC_011726.1|WP_012594221.1|908815_909517_-|hypothetical-protein
MNRLLKGLAISVLAVTLGIINPVSATQWVYLGTSQDNYSYYLDFDSLKGTGNSRSFWVKRVNNYGETESLIKSSIDCHYRQIGVIESIRYNVDGSVRSHDIIDSNTGGTWAFAPGTIAQTYYDFVCSRITLQPEPQIAMTTHEYPKAACGDPSNSTLGRQRWYPVFVDYSPEDLRYIKKNLCRDAFRITRQDGSLSIQVASFTTKRNAEKFAAFLEQELGNSEVGNPTIIVIR
>NC_011726.1|WP_012594220.1|908345_908786_+|SufE-family-protein
MSASSTPLPPNLENIVQKFKRREDPKKRYEQLLWYAKKLESMPEDGKIPENKVQGCVSQVYITAALKDGKVWYQGDSDAQLVKGLVAFLIEGLNGLTPGEILQVTPDFIEETGLKVSLTPSRANGFYNIFQLMKKKALGLQLETSV
>NC_011726.1|WP_012594219.1|907047_908157_-|hydrogenase-formation-protein-HypD
MKFVDEYRDATLAQQYAQKIAEITTKKWIIMEICGGQTHSIVKYGIDALLPPEITLIHGPGCPVCVTPIELIDYALAIASLRDIIFCSFGDMLRVPGTDKDLLTVKANGGDIRIVYSPLDCLKIAQDNPKKQVVFFAVGFETTTPATAMAVYQAAQQRLNNFSLLVSHVLVPPAMEAILGSPNCQVQGFLAAGHVCTVMGYEQYNPIAKKYGVPIVVTGFEPIDILQGIYLCLQQLESGQAYCENQYIRSVQETGNVVAQQIIQEVFEVVPRRWRGIGEIGESGLGLRQKYALFDAIKRFSTDLSYVSPSAVPSVCISGEIMQGYKKPHDCPAFGTQCTPEQPLGAPMVSSEGACAAYYRYRSYQTVNN
>NC_011726.1|WP_012594218.1|905880_906921_+|GTP-binding-protein
MTQTLSIPKSSHLTLPKRGMPVTIITGFLGSGKTTLLNHILTNNQQLKVAVLVNEFGDIDIDSQLLVSVDENMVALSNGCICCTINDNLVEAVYQILEQADKIDYLILETTGVADPLPIALTFINTELRDMTRLDSILTVVDAETFTPEHFESEAALRQIIYGDIILLNKTDLVDQEKLKILEEELNRIKSGARIIHSQHSQVPLPLILDIDVNNHQNYCTEHITDHHHHDHHHEHDHRHHHDHHHHDHDHLTIDGFVSISFESDRPFIVEKFQNFLVDDVMINVFRAKGIIWFKESQLRHIFQLSGKRYDMNADQWITSPRNQLVFIGRNLDKEMLTKQLNQCLA
>NC_011726.1|WP_012594217.1|905166_905811_+|GTP-cyclohydrolase-I-FolE
MTLSQPKELNPTLPKLITQSQPPVTEEEMRQAVRTLLLGLGEDPDREGLRDTPKRVVKALKFLTSGYHQSLDELLNGAVFHENTDEMVLVRDIDLFSSCEHHILPILGRAHIAYIPDGKVIGLSKIARICEMYGRRLQVQERLTAQIADALQGLLQPKGVAVVVEATHMCMVMRGVQKAGSWTVTSAVRGLFAEDAKTRQEFMSLIRHSATFHH
>NC_011726.1|WP_012594216.1|903992_905069_+|WD40-repeat-domain-containing-protein
MFNLKPTLQTLFELQWSRKLADYVTDLSWSNRDYLAASSGIGEVLLWNFNTEEVNLILSPEDTQEKSIDCLQFSADGQFLAAAGQEGKVRIWQILPELQLLNHWGKEGQWIEQLAWHPTQNLLAFSIGRYVQIVDIFAEEIIVTLPFESSSVLAIAWYPSGERLAIAGNGGIKIWKNNSWDEEPIVLEMPAACTAIAWSNQGEYLAASCLDNTVLVWRFPEDNPWRMVGFEGKIRQLAWSTIPSGIAPLLAVACQNTIVVWKKQKTDKEGWLSRTLIHHEAVIKNVVFQPNTLLLASVGTDGLLLFWKKAEQLTQSLEGVSTEFSRLIWHPLGKKLALGGANGELLILTQSTRGKGFG
>NC_011726.1|WP_012594215.1|903033_904005_+|GTP-binding-protein
MVMVKSLETVPVTVLTGYLGAGKTTLLNRILTHEHGKKVAVIVNEFGEVGIDNQLVIDADEEIFEMNNGCICCTVRGDLIRIISNLMKRRHKFDHLVIETTGLADPAPVIQTFFVDEDMREKLLLDAVVTVIDAKHIQQHWEADEAQEQIAFADIILLNKIDLVSPEELDRLEKRLRGINRMAKIYQTQNTEIAMNYLLGIKAFDLNYALEVDPNFLSEDAHEHDSSISSVSLVELGELDLQKVSNWIGELLRTQGTDIFRMKGILNIQGMAERFVFQGVHMLVDAQPDRPWKPQETRKNELVFIGRNLDEMKLKEEFRACLI
>NC_011726.1|WP_012594214.1|902692_902866_-|metallothionein
MTAATVTQMKCACSSCVCIVDLSDAIQKDGKYYCSDACANGHPDGAGCSHHGCECHS
>NC_011726.1|WP_012594213.1|902306_902696_+|helix-turn-helix-transcriptional-regulator
MKTDTDISEESDELLKCHPHPLETVPLTIFQNQILSVEKAQRMAEFFSLMGDTNRLRILSLLAHQELCVCDLAAILNMSESAVSHQLRTLKAIRLVSYEKRGRKVFYSLQDHHVLELYESVAEHLDEVD
>NC_011726.1|WP_012594223.1|913239_913749_-|transcriptional-repressor
MPPYTATSLKAELNARGWRLTPQREKILHVFQNLPRGNHLSAEELYELLEERGEGISLSTIYRSVKLMSRMGILRELELAEGHKHYELNHPSPNHHHHMVCIQCNKTIEFKNDSILKHSLKQCEKEGFQLIDCQLTVMTICPEAIRMGWPSSLPSNWSCIRAISESESC
>NC_011726.1|WP_012594224.1|913945_914827_-|D-alanyl-D-alanine-carboxypeptidase/D-alanyl-D-alanine-endopeptidase
MKFLRSFPHILAIVALATTAWTSPSLGNEINSIPDDTQYLQEEPIDIYVPPPETGAPGTCAALIEPAINKIIGRYQNNWGILAETLEGGTTLYSHNPDKFFIPASNTKLFTTAAALQRLNPQGKIGSKSVQNWINVTNINSNNYYADTLLKHIGGASVAKSILAQIGVDPNSFRLADGSGLSRKNAATPRALVTTLRSMHYAPGNNVFYASLPVAGISGTLRNRMKNTTAQGTVYAKTGTLRGVRALSGYMNHPYFGQVIFSILANNPSVSGSALVSSIDQIVLQISRTKPCN
>NC_011726.1|WP_012594225.1|915002_916025_-|long-chain-acyl-[acyl-carrier-protein]-reductase
MFGLIGHLTSLEHAQQVAEALGYPEYANQGLDFWCAAPPQIVDHFHVTSVTGQIIEGKYVESCFLPEMLVNRRIKAAIRKILNAMALAQKADLNITALGGFSSIIFEEFNLKENKQVRNVELEFERFTTGNTHTAYIICRQLEQVSAQLGLDLSQATVAVCGATGDIGSAVCRWLDQKTDVAELLLIARNQERLQGLQAELGRGKIMELEEALPQADIIVWVASMPKGVEINPETLKKPCLIIDGGYPKNLGTQVQHPDVYVLKGGIVEHSLDIDWKIMEIVSMDIPSRQMFACFAEGILLEFEGWHTNFSWGRNQISVPKMEQIGEASLKHGFRPLLSW
>NC_011726.1|WP_012594226.1|916312_917488_-|hypothetical-protein
MQLSSDVFNNSVQYLENHQESLRIRKLIFCLAKKSWENDPNILNSYSLKELILELVQIIPNRDQLKLSLYKLVKSLNRPKVYAPVAKIIFDQIDYIYRDSHQDNDFLEEVDVPVQSTHITNKEFLLEQAVESLNKHEQSERIKKLIFALSREQWENNLDQINSHGLKNLISELLQKYPNRADLEIAFNQLIGKINKRNLYLAISKVILTKLEAFYEDLSVSIDAKNQTIVSSYSTQIIPLNNINYTPNQSGKNNQFQDLAFDTSVIDITSEQMKTEIQQIRNSVSVPPPPAPKTKTYDIFELRLQIVQYTNPLQAKILLFSLLFHPWDRSGQDWSMLRSYTLDDLLEQLLQSGKPLAEIESKLYTAAKSLKDHEPYLQAASTLVETIKPFV
>NC_011726.1|WP_012594227.1|917833_918520_+|hypothetical-protein
MATFNSVIQSNDKTMIQVAVLLTRYGFDLGGLSPLEVIDKWLTSYSAHWIRLAIVEALYQGRYKAVSIEQILRLWQRRSRVTFHFNHEFERLICRHLLLEHSTPTNNQPQSSLKNLQHHIADEQDSVETSLILDHTIKTPESSQVSLPIPRENAPKIFNDRHPSSVSPLTKIDSEPDPSDHKPSVSYQTPLMLTDGKTPSSIHQFVPYADDSHLYTKLRAVLHQRLVE
>NC_011726.1|WP_012594228.1|918549_919632_-|heat-inducible-transcriptional-repressor-HrcA
MTIPTPLTKRYQNILRATIQHYIATAEPVGSKTLVQEYNFSVSSATIRNALGQLEKAGLLYQPHPSAGRIPSDGGYRIYVDNLITPDDRIGQKIEQHLSQKLAKESFSFETLIHRATQILANFSGYIALITLPQTSANQLRHVQLIPASAKQVILIIVTDSYQTESILMDLPQSVLNEDGQNEELLAQELQLISNFLNTHLKGKNLSDLMALNWQKVDQEFVQYTEFLKLLLFQLQEHLKSSISTPIMIHGLSEVLRQPEFSQLQQVQMLLHLLEEQQDQLLPLIFDLPRNQSLTKGVTIRIGSENPLEPMRPCSLISAVYQQRDIPVGSVGVIGPTRMVYENIIPLVESTADYLSEALS
>NC_011726.1|WP_012594229.1|919796_920156_-|hypothetical-protein
MYQYQSLPQITVTELAARLNQLEHLEGKIQLIDVREPHEVDIAYIEGFEVLPLSQFAEWSVHIKSRFNPDVETLVICHHGMRSAQMCQWLLNNGFTNVKNIIGGIDAYSLHVDPAIAHY
>NC_011726.1|WP_012594230.1|920332_922018_+|DUF3352-domain-containing-protein
MKLRSFFITLAISVLILLSLAGGSLYWILAQSPLNLVSGGVLREPITAIFVPKQAPVMISLLVNPDRLEALAKLIAFPQNRRRSHQQFLTLEKQLLAQTGLDYSSQIQPWLGEEITLAVTSLDFDRNPDNGVQPGYLLAITTKDSQLAKEFLQSSYSKDAIAGTSDLIFEPYKGVNLIYQKNRDTDVNQTLSATAILNNVVLFANHPKILRDAINNVQVPDLNLKQSPSYQEALKTITEPRIGLIYANFPSLSAWLGNLPLPELPEITQTLTVAFSVKSEGLVAQTALIGGSKAQDRLPVLSQPVSTLAYIPPNSILTAAGTDLNQLWREIETGLATESPLQQVLNQAITSLQEPLGVNLPKEIFPWVEGEFSLGLLPHPHSGEPDWIFVAQKVPGVNMSEILEKLDELAQEKGYSIGNLPLLDTTVTAWTKLTTAKGNHNSSLTQLAAQVSGLYSETDQYVIFATSVEAMSQALSTSENTIIRSEKLQQAIAGLSAENDGYLYIDWSQGQKLLEQKFPIVKVVELSIKPLLNNLRSLTISSQGSQNSIRRGTVFFNLGVR
>NC_011726.1|WP_012594231.1|922055_922496_-|hypothetical-protein
MKFRAIAFFLVSGLLWLSTAWFTPPALALTPIKILDIDYKNCPSELAEGNVTSGGSSLPADCYILIGKAQNLSGKMVYDADVFGRVYDANNEPILQNRSRLGSIPEVPPGISEFELRITVPSDQPTPLKLKQFKASGFTNKVDPIF
>NC_011726.1|WP_012594232.1|922699_922975_+|hypothetical-protein
MIESSMNGLDEIQLPREERVIEIKNLIETLHIADEIASKGYLITSSELADLMNINPSAVTSRGNEWNWRNWLVSKVRREGNQYLWQLERVD

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Crispr_ID: NC_011726_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_5

1733348-1733534

Unclear

Consensus_repeat	Method
TGTGATTCATGGCTTCATGCCGTTAGGCGTTGCTCAA	CRISPRCasFinder

2 spacers

cas5,cas7,cas8b3,cas6

The CRISPR arrays of NC_011726_5

>merge|NC_011726|5|1733348-1733534|CRISPRCasFinder
TGTGATTCATGGCTTCATGCCGTTAGGCGTTGCTCAATCCTTAAAAAATCGGGCTAAGTGTTAAAGAGGCTCAACGATGTGATTCATGGCTTCATGCCGTTAGGCGTTGCTCAAGGAAAATATCCAGGGATTTTCGTCCCAATTAACTGACGTGATTCGTGGCTTTATGCCGTTAGGTGTATTAATT

>NC_011726|5|5|1733348-1733534|CRISPRCasFinder
TGTGATTCATGGCTTCATGCCGTTAGGCGTTGCTCAA	TCCTTAAAAAATCGGGCTAAGTGTTAAAGAGGCTCAACGA
TGTGATTCATGGCTTCATGCCGTTAGGCGTTGCTCAA	GGAAAATATCCAGGGATTTTCGTCCCAATTAACTGA
CGTGATTCGTGGCTTTATGCCGTTAGGTGTATTAATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_012594976.1\|1729302_1729968_+\|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6	cas6	cd09703_cas6_CAS-I:CAS-III	gnl\|CDD\|370559
NC_011726.1\|WP_012594970.1\|1720462_1720738_+\|TatA/E-family-twin-arginine-targeting-protein-translocase	unknown	unknown	gnl\|CDD\|184859
NC_011726.1\|WP_012594981.1\|1738828_1739818_-\|TniQ-family-protein	unknown	unknown	gnl\|CDD\|377670
NC_011726.1\|WP_012594987.1\|1748041_1748653_-\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|368559
NC_011726.1\|WP_041229619.1\|1739814_1740936_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379165
NC_011726.1\|WP_012594980.1\|1733636_1738787_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|99707
NC_011726.1\|WP_012594979.1\|1732460_1733099_+\|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	cas5	cd09688_cas5_CAS-I-B	gnl\|CDD\|187819
NC_011726.1\|WP_012594974.1\|1725123_1727169_+\|biosynthetic-arginine-decarboxylase	unknown	unknown	gnl\|CDD\|235427
NC_011726.1\|WP_015783767.1\|1723830_1724880_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl\|CDD\|239551
NC_011726.1\|WP_012594984.1\|1744065_1744260_-\|addiction-module-toxin,-HicA-family	unknown	unknown	gnl\|CDD\|224638
NC_011726.1\|WP_012594971.1\|1720812_1721430_+\|molecular-chaperone-DnaJ	unknown	unknown	gnl\|CDD\|371751
NC_011726.1\|WP_012594977.1\|1729964_1731512_+\|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1	cas8b3	cd09713_cas8b3_CAS-I-B	gnl\|CDD\|187844
NC_011726.1\|WP_012594975.1\|1727757_1729149_-\|TniQ-family-protein	unknown	unknown	gnl\|CDD\|377670
NC_011726.1\|WP_012594985.1\|1744252_1744477_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NC_011726.1\|WP_012594983.1\|1740929_1743698_-\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|366234
NC_011726.1\|WP_012594986.1\|1744613_1747631_-\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|227226
NC_011726.1\|WP_012594972.1\|1721556_1723704_+\|intein-containing-tRNA-splicing-ligase-RtcB	unknown	unknown	gnl\|CDD\|376465
NC_011726.1\|WP_012594988.1\|1748670_1749831_-\|lipid-A-disaccharide-synthase	unknown	unknown	gnl\|CDD\|234580
NC_011726.1\|WP_012594978.1\|1731492_1732464_+\|CRISPR-associated-negative-autoregulator	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NC_011726.1\|WP_012594989.1\|1749853_1750684_-\|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase	unknown	unknown	gnl\|CDD\|235390

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_012594976.1\|1729302_1729968_+\|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6	gnl\|CDD\|370559	pfam09559, Cas6, Cas6 Crispr. The Cas6 Crispr family of proteins averaging 140 residues are characterized by having a GhGxxxxxGhG motif, where h indicates a hydrophobic residue, at the C-terminus. The CRISPR-Cas system is possibly a mechanism of defense against invading pathogens and plasmids that functions analogously to the RNA interference (RNAi) systems in eukaryotes.	1.53426e-90
NC_011726.1\|WP_012594970.1\|1720462_1720738_+\|TatA/E-family-twin-arginine-targeting-protein-translocase	gnl\|CDD\|184859	PRK14857, tatA, TatA/E family twin arginine-targeting protein translocase.	8.01853e-41
NC_011726.1\|WP_012594981.1\|1738828_1739818_-\|TniQ-family-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	2.28526e-18
NC_011726.1\|WP_012594987.1\|1748041_1748653_-\|Uma2-family-endonuclease	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	2.23026e-29
NC_011726.1\|WP_041229619.1\|1739814_1740936_-\|ATP-binding-protein	gnl\|CDD\|379165	pfam13401, AAA_22, AAA domain.	4.33344e-06
NC_011726.1\|WP_012594980.1\|1733636_1738787_+\|ATP-binding-protein	gnl\|CDD\|99707	cd00009, AAA, The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.	3.04193e-07
NC_011726.1\|WP_012594979.1\|1732460_1733099_+\|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS	gnl\|CDD\|187819	cd09688, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.48375e-76
NC_011726.1\|WP_012594974.1\|1725123_1727169_+\|biosynthetic-arginine-decarboxylase	gnl\|CDD\|235427	PRK05354, PRK05354, biosynthetic arginine decarboxylase.	0
NC_011726.1\|WP_015783767.1\|1723830_1724880_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl\|CDD\|239551	cd03469, Rieske_RO_Alpha_N, Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth. ROs consist of two or three components: reductase, oxygenase, and ferredoxin (in some cases) components. The oxygenase component may contain alpha and beta subunits, with the beta subunit having a purely structural function. Some oxygenase components contain only an alpha subunit. The oxygenase alpha subunit has two domains, an N-terminal Rieske domain with an [2Fe-2S] cluster and a C-terminal catalytic domain with a mononuclear Fe(II) binding site. The Rieske [2Fe-2S] cluster accepts electrons from the reductase or ferredoxin component and transfers them to the mononuclear iron for catalysis. Reduced pyridine nucleotide is used as the initial source of two electrons for dioxygen activation.	3.32693e-35
NC_011726.1\|WP_012594984.1\|1744065_1744260_-\|addiction-module-toxin,-HicA-family	gnl\|CDD\|224638	COG1724, COG1724, Predicted RNA binding protein (dsRBD-like fold), HicA family [General function prediction only].	3.20882e-17
NC_011726.1\|WP_012594971.1\|1720812_1721430_+\|molecular-chaperone-DnaJ	gnl\|CDD\|371751	pfam11833, CPP1-like, Protein CHAPERONE-LIKE PROTEIN OF POR1-like. This entry includes proteins from bacteria and eukaryotes. The plant member, CHAPERONE-LIKE PROTEIN OF POR1 (CPP1), is an essential protein for chloroplast development, plays a role in the regulation of POR (light-dependent protochlorophyllide oxidoreductase) stability and function.	2.79723e-80
NC_011726.1\|WP_012594977.1\|1729964_1731512_+\|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1	gnl\|CDD\|187844	cd09713, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-C subtype; also known as Csx13_N family.	2.87605e-72
NC_011726.1\|WP_012594975.1\|1727757_1729149_-\|TniQ-family-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.78236e-15
NC_011726.1\|WP_012594985.1\|1744252_1744477_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	3.32191e-12
NC_011726.1\|WP_012594983.1\|1740929_1743698_-\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	3.24624e-10
NC_011726.1\|WP_012594986.1\|1744613_1747631_-\|N-6-DNA-methylase	gnl\|CDD\|227226	COG4889, COG4889, Predicted helicase [General function prediction only].	0
NC_011726.1\|WP_012594972.1\|1721556_1723704_+\|intein-containing-tRNA-splicing-ligase-RtcB	gnl\|CDD\|376465	pfam01139, RtcB, tRNA-splicing ligase RtcB. This family of RNA ligases (EC:6.5.1.3) join 2',3'-cyclic phosphate and 5'-OH ends. They catalyze the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced RNA damage.	1.79141e-147
NC_011726.1\|WP_012594988.1\|1748670_1749831_-\|lipid-A-disaccharide-synthase	gnl\|CDD\|234580	PRK00025, lpxB, lipid-A-disaccharide synthase; Reviewed.	0
NC_011726.1\|WP_012594978.1\|1731492_1732464_+\|CRISPR-associated-negative-autoregulator	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	8.53856e-14
NC_011726.1\|WP_012594989.1\|1749853_1750684_-\|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase	gnl\|CDD\|235390	PRK05289, PRK05289, acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase.	3.18654e-149

>NC_011726.1|WP_012594979.1|1732460_1733099_+|type-I-MYXAN-CRISPR-associated-protein-Cas5/Cmx5/DevS
MNTPLVIYLDVPFVTFREFHAREMGRTYPVPPPATVYGMLLSLVGETDVYRHCGVELAIAMLSEAKKSRILRQMRRFKQKDFSHAENVNPSYQEILSNLKCLIWVRSEAEMMQPSLKERIEFTFERPELVRRFGCLFLGESDQLIKTIRLVSEDYREGVRRWLIRDNGGRLTLPYWVDHLGSRNTRFLRYRVEEMNQLSPPDFAWTSIQSSV
>NC_011726.1|WP_012594978.1|1731492_1732464_+|CRISPR-associated-negative-autoregulator
MNQKKNKIPNYYLYGTVLTRYGLASLSHGMRQGNKSILQKAYWDGKIHSLVGSSSLRWALRFYLQEEGYPVNRVWDKDEHINRLTDDNFNPDQFYDDDIFGFALLESVEEETVEDKTQPSTRRRGKRKKSGTTAQRTGALSMNNAISLTPYDGSLKLGAKSGRDKDSTSLHFTEYHNTRYQYYFGLNATHLKDCSRIFPLIDGIMDMPKVGGSANIFSYPFCPDSLVFQWTNHFASYISYCFESVDGKGRNIKLTQDFINEVECGQINPDELWIGGAIVNDLRELENFEKSLLKQIHLYRNRNELVADLKEVIKQDLGLKDSQ
>NC_011726.1|WP_012594977.1|1729964_1731512_+|type-I-MYXAN-CRISPR-associated-Cas8a1/Cmx1
MTVATQSKISLSLTACDTTIMHRAGMAGLYLTLKRLEEKYPDFRQREGNLSWSLTPDTIDLFWEAIDFSALDWLLKESFQLDDNGLICLTGLDDYSELRQKIELNEAIKAVFLRHNKFYQAGEAKKISFTVEEREVSYSYKPLIWYAHQTFAKELCDTDTQQLKQDYLQITSWLYLGGIVRHARADKKTKLEEKPEYALALLFVPVVCHYCLFHLPSEDVNSRKPHRYLVVIPEINNFEDASRRRWRLQQLEPQQLHVTNMSEAGLLYYSLDEIQANENYSQACQVWLYEKMNKASYQRVLTMVEEIEIDKEMITTYQQVKQYFQPNYQHIYPNNILIEVNLVRSLIAENLRQKQPWWFNFWKKLIDEDSKNYLFKQLLSNQKGVKFMTKNSERDEKYLAFIEVFQQAMRANFAKIYAKTERGKNPLFQKKAERLRAELNCCYDEISFQHYLADFLARGGLNKPLQGQKREVLLLIQQVPWEKLRIWALLGIASYEPKPKNLQELEGIKDESEEE
>NC_011726.1|WP_012594976.1|1729302_1729968_+|type-I-MYXAN-CRISPR-associated-protein-Cas6/Cmx6
MTDTVINSEEHLDMIFKLRGAPIPLDNGYVIYSALCRICPTLHELKDVGIHPIAGIPTQNKFLELTPNSCLKIRIHHLQIPIIYPYLTGQTFEIGQESYQLNIPDYQAIRSSDSLYSRLVVIKGYQDSSSFLEAVQRQMDSLAIQGNVELLTRQNGTPQRRQLTIRKQGNEFKIRGFGVKISELSPEDSLTLQEQGIGGKRKMMCGIFVPATRPKDERKTP
>NC_011726.1|WP_012594975.1|1727757_1729149_-|TniQ-family-protein
MDIDINKIQPYTNDELWSPEKFPMPPRSRLHHLQPMGIGTPMVESLTSYVTRLAHSHGVHVGTLIYKEIIPCISKTYKTTNLLCLRNQTGAINGCGLLAEDSVQALSELTLYQNLSNLTMLNWKNIFPNRKLIRNHKAWCPFCYQEWRTNNQIIFDPLIWQIEVIRLCSIHQYSLQTLCPSCKKSVSVLSPKNQLGYCSNCSNWLGNIEDYLNTSLSIHTKFKDKSYFLWIADCLGNLLSFPSTIKSPSKKQISQIIQAIIHQSTKGNIAEFARWANMPKNTVWMWVKGKSLPQLSRLLALCYLCRVDLLDSIINEGNITNMILHQKSIPSSVNERPKIFKNTLNHAQIHAALSEAFQETHPRPMTQVAKRLGISNKVLRRHFPELCKKISQRYLIYKKQSRLERIQKVCIEVEKAVKQLQQQGIYPSEQRVALHIGQPGCFRDKEVREVLNRTRRNWRLLDT
>NC_011726.1|WP_012594974.1|1725123_1727169_+|biosynthetic-arginine-decarboxylase
MKETLQLETSPLNNSKKTSTWTIENSENLYYIKGWGEPYFSINAAGHITVSPQGDLGVSLDLYELVQSLKKRNISFPLLIRFSDILADRLARLNASFDRAIARYNYPNKYQGVYPIKCNQHRHIVETIVNYSKSYQFGLEAGSKPELMIALATLDPSLIAPNYAPIIICNGYKDPAYIKTAILATQLGYKPIIVIEQLEELFLTLEISKQLGIEPSLGVRAKLSTKGSGRWGNSTGDRAKFGLTIPEILTVVEYLKSEENLHYLQLLHFHIGSQIASISVIKDAIREASQIYIQLAKVNPNMQYLDVGGGLGVDYDGSKTNFYASKNYNMQNYANDIVAEVKESCEAANIEAPILISESGRAIAAHHSVLIFDVLNTNDVCTTPPEFIAENDNLIIRNLWQTYESIDVKNYQETYHDAIQFKEEAISLFNFGYLSLAERAKAEQLYWACCQKILEITRHQDYVPDDLEDLEKTMASIYYINLSVFQSAPDSWAIDQLFPIMPIHRLDEEPTQRAILADLTCDSDGKIDQFIDLRDVKSVLELHRLKTLESGHHETQSKGKKIKNETKMAEPYYLGMFLVGAYQEIMGNLHNLFGDINVIHISMSTKGYEIEHLVKGDTIKEVLSYVQYDAEALLESMRQRTEKALQDHRLTLEESQQLLQDYEENLNHYTYLVSDQEKSKS
>NC_011726.1|WP_015783767.1|1723830_1724880_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MSSLLRNAWYVALPGKQLKPGKMTHKKMLGEPVLVGRREDGEVFAMRDICPHRGIPLQYGWLEGDGVCCCYHGWKFNTSDGRCSEIPSLTEYDDLDISRIRVPTYPCREVQGNIWVYFAEDSKKEINPSELPPVPTIPDFGKVEPGISETIHFACHIDHAIIGLMDPAHGPYVHSSWWWRSGPRKFRVKEKQYEPVAQGFRLVPYDMPVSARPYKILGNQVSIEIVFELPSVRTEILRGDRYSACLLTTITPIDENECEAFQSIYWTIPWMGLFKPLLSLLTRQFLAQDRDVVIQQQEGLKYNPALMLIDDADTQAKWYFRLKQEYQKSQAENRPFKNPVEPRILRWRS
>NC_011726.1|WP_012594972.1|1721556_1723704_+|intein-containing-tRNA-splicing-ligase-RtcB
MPYEPLKLSTPTPVLSWANHRLGLEETQMAKNMASLPFVFKHIALMPDVHLGKGALVGSVIATKDAVIPAAVGVDIGCFTGDTLIPLIDGKSYPLRELADSGKPIYVYSCTKTGKIVATEAIARLTRQNAPLVKVILDNGVEIKCTPDHPFMLRDGEYQEASQLRKGTSLMPFYSKVDRDGYTLIQQNYSGRWQKAHWIIARSGLLGKVPKFENQRTVIHHKNFNQADNSPDNLEFMGNRDHSAYHGSLVDRSTHWQSPEFEKQRKDALAAKSKTSEGYQYYAERGTRNILQYMQNNPEHFQQSVSGNGERGKQYLVHYNQSPKGRAKSKEIANRFYTCEIYGEQVKSPIGLDNHRKYQHTYNHKVVDIIFLNESQDVYCLSVPEYHNFALSAGVFVHNCGMAALKMPFTADQLEVKLKQIRLEIEAAIPVGFEENKDAEKAVTNWQGWREFKELHRGVKDLETKAIRQLGSLGGGNHFIELCLDTDDQVWLMLHSGSRHIGNKLAECHISTAKNLAKLAQISLPDPDLSYFVAGTPEFAAYWHDLQWAQEYAKFNRDVMMNRFKKIVEKHLAGGKPTKPLLSVNCHHNYAEKEVHFGEEVYVTRKGAVRARTEDYGIIPGSMGAKSFIVKGKGSYESYCSCSHGAGRLMSRSKAKKQFSIDDLVAQTQGVECRKDSGVLDEIPGAYKPIDQVMENQADLVEVVATLKQVLCVKG
>NC_011726.1|WP_012594971.1|1720812_1721430_+|molecular-chaperone-DnaJ
MNEQTPYEILGVSEESSFEEIQDAKNRLIQEYKDNNKVIENIETAYDAIIMERLRMRQEGKIKVPDRIRFPERSEEILPTVPSVSLNNSPSWLQRLIDTPSSQDLIIAGGVFAALVTLTIFAQVSQMALILVLGVFANVYLLNRKEQRFGRSLLMTLVGLLIGVALGTGLTNLMGGANLIVALREDQLASIVTLIIFWLISSFLR
>NC_011726.1|WP_012594970.1|1720462_1720738_+|TatA/E-family-twin-arginine-targeting-protein-translocase
MNVFGIGLPEMVLILVIALLVFGPKKLPEIGRSLGKAIRGFQEASKEFENEFKREAQQLEESVTMKAELEGNQTSESSSSEKPPINGVEKS
>NC_011726.1|WP_012594980.1|1733636_1738787_+|ATP-binding-protein
MPLSGGATDKIGNRYEGLWTIDCLLDLIDEKANNIEIEFISLNHLNEQATTIRLEPVGEEGEGVEFWLQREDIREYHQVKRQNTKGRWTLADLETKQILTNFKKKLENNQTHCYFISINNAYQLEELAERARSSQSWIEFVREFLDAKDWRESFHDLVKYWYKYQQLEIEQAIEDFKSGKLSHQQQAIINVAENSYEKLKRIYVETISERKLRQTVVDNIKRLIESKSNDFPSHTDYQTAVDILAGFALDSIHKILTASDIWKHLDTRGYQRCNYSKNYHVLAAIDKANQLYLSPLEKQTVIAGQSIPRQEAEEAFNLLVNTQNKKGVFLMGEAGVGKSGVMLQIAKKLEQENITFFVFRIDNLPPEVNPDDVGRKYRLPLSPTIILANISKYSQKQTVLIIDQLDAVSQVSGRNPQFFDCIHSLLEQTKQFSKVRVLVACRKFDLDNDSRIKNLIGKQGILETVEIQRLSSEQVKQTVQNLGLDASKLNQKQVDLLSLPLHLGLLAQISQDSTINNLNFETANDLFDKFWEFKQTKLYGDEKTKHLVQWNEVIDKICDNISTKLNQTLSISKYLLDDYLIDTRIMISENVLIQEQDKIKFFHENFFDYAFARRFTAREKQLLSFLREDEQHLFKRAQVRQILQFERSINFNQYLYDIEELLNSKLLTSEDDRKQLLNSEDIRIRFHLKQLVISLLSNLENPAEEEWEIIHLFLTDNESSLFNHAWGILYQPQWFMLAKDLGIIEQWLRDDNDLIVDKTVRLISSTASQLPDEVSPLIEPFIENSSEKWLDRFLYIADRISFELDKSRKLLDLFLTLLNKEKLDNLRDTLAMNGDFWTLIFSISEKNSAWTCEIIGHYLNRRLELYLMQIWLLHWIYQCCLNIHPSFLKQYTQLTIRLNPFDTYSYNLKQDKATIPDTQHTEIFLKSADKAPKDYVINVLPFMLSVIELTSIKDDEKPYEDNVWYYRSYGGGHGIESAIFKGMEIALSNLARNNPEEFTQIIDKYNLLSSGSETIQFLLIRAYTANGFKFVDEIVEYLCDKPYRLETGYSGVSDNSLSARFWASRQLIKAILPYCSQNHLDKLEQLILTYGSFNNDWPKYHPQIIINLNYKHAKFLDVQLISHYPEIIVYLAIYDYYKELKELLYISRNWLRRKREYPQFIILDGINDILIEQFVKLVLIKFNLIQNIFSFSRLLFLNTKFFIPSQRLTQRFFELQRKFMSLGWIKASESIKPTPIGEIASVVSSPIPKNATEKMTDEQWLEAIKTYDCEHENKMGDLIGEAYELSDNLEKEVKKDPYRFAKLIDQFPDNTNLYYFNAILRGIAETEVEIEMETVLNVCQRCHQLPHKPCGREISQTVTKLAYLPWDEIGFDIITYYALHDPNPDKEWQPFQVINGDQSLANDIYIKGINSVRGRAVEAIAHLIFKDKERTVYFKEALQQMVKDPFLAVRSCVAHALIAVLNYDRDLAINLFKELVDTEDILLSTQTINRFLYYALGTHYTDLKPIVERMINSQIPEVQEVGARSLFLVSLINSEAQLLAENYLSGKLSTPAHRKAAAFIYINNLRQADHREFCEQKLIQLFNDTNQEVQEQAAGFFSNLEPQDLTNYPKMIEAFINSSVFVKKSFHLLHLFTTIDKFDKQLAFKVCQRFVNVFLLESPNRNGGYSNQLQYVSQIIIQIYSQTRDSKLQSSCLDVIDNLYRYMVDELNQATQEYDR
>NC_011726.1|WP_012594981.1|1738828_1739818_-|TniQ-family-protein
MSIYEEFWSSKPLKLPPRSRLFCLKPMGVGTCYTESLSSYVNRLAQEHCLTSQKLIMAEIAPLILKNEDKSDLLKKSVSHLLGNTDAKPVINGMREMTGELVRVLEQLTMRQDLRFLTLLSWKGMIYDRQLFKNYRAWCPCCLEEWKGEKKVIYEPLLWSFKDVEVCLLHKQRLIEECPHCNARLPVFARLSPVGFCSRCRGWLGDKKEEMEEVEPHRVNIEGIGDLIAVTPKMAYKPIPIELTRKLEVILLAFEEACGKDITLLGDLGVIMEQMRIATKQHQNKPYHLVKLVIPVCEKANIRVSELLLLNFKALSDRVFENLELGMRL
>NC_011726.1|WP_041229619.1|1739814_1740936_-|ATP-binding-protein
MVMTEKRLFSWELLEDSTENKLKYFKDVIIPHRNIKTILEQLLKNAIEPDDALVYLVFGVTGVGKSRLKAEFEKRLLRHFEAEIIANPGSLVVGGIEVDGAEGGKFNYSDYYIQVLESLQEVLIDYKENYEIDEDDNEDNLRGDHEGKNSKALRRTMQKVFTHRQLKAYTLDEAQHLFDVAGGRQINVQMNWLKSIANKTQTVHVLFGTYDLLKCQEVNGQVGRRSEDYYLPPYYLDNSDDQKEFKKAINTLQRHFPVENEPELNEKWEYFMEYSIGCIGILKSWWYRALKNALDDGAKTVRIKDFQARELSSGRRKTIKKELEDGERRLAALYFEEKAKKPKSESQASSKSSTRKVGERKAIRDLVGVNQEG
>NC_011726.1|WP_012594983.1|1740929_1743698_-|DDE-type-integrase/transposase/recombinase
MLSDTEFQTWCDGMQLSQRQRELITQVRTSPPIRKVKGSARNVHGRYPSKKMGTTIQFESHTVELPALCEFYEYDDSVLEYWDQPYKFTIKCAPEGRQATTITHYPDFLVLRKNSCGFEEWKKETKLEKLSEKQPYRYQKQEGIWIDTIVGEYLENLGYYYCVRSDREIDWVKYRNQKYLQSYKHGYLDQQYIIDTAVEEELKDIINHNPGIDLTTLLNKAQNATIDDINTLIALEKVYVDLSVVPIEEQLDKVHLFRDKATAEAYITATHNYSEPITGSVQIVNLKVGSSFLLDGKSLTIDHVGDSKIILKGEQGIIRWTHAEFQQLLELGEITHLETEEKPALDEEGWQYFVEASPKALETANQRYSAIKPLLDGETYSSLDIDISARTLRHWKAKYQKAQQDYGCGFLGLIPQSKGNPTPRYSDEDVEFVDKIIEEQYETFKQKNAWQTYLRLRDRWKESGRTSPIPSHTFYYERIKKRNSYQQTKRRMGSRAANNLLRPWLIELTTPRHGSRPFEICHIDHTPLDVECLCPYSNKNLGRPWVTGMIDAYTRRILALYLTFDEPSYRSCMMVMRICVQRFGRFPELIVVDNGKEFSSTYFETLLARFEATKKHRPKDVPKFSSIIERWFGSQNREFINNLRGNTQIMKHVRLVKKENNPKNLATWTLDELYDYLAFGYAYGVYDRMQHPALEGMSPQQAYELGLAKTGHRPHQYIKYDEQFKILTLPTTQKGTAKVIPGTGVRINYQDYWTDEFYRVENQSVPVRYDPLDYGVAYAYINNHWVKCLSNYHLRFQGYSEKAVAIATTICRQKRKQSNQSLYVGANELVSLLKNAEDYEELMLQIRKDQSAKLVYNLIEGNLSSAVLNPADIEHPFLQDDSKVDNNFSNLDEDILQPSLSTTTQSDNEDDDIGFYSNEELW
>NC_011726.1|WP_012594984.1|1744065_1744260_-|addiction-module-toxin,-HicA-family
MPKFPRLTDKEAEKLLLNAGFILLRTQGSHRIYFKDNIRVVIPFHSGEILHPKIIKQILNAIDR
>NC_011726.1|WP_012594985.1|1744252_1744477_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MSYQISVIIEKDEDGYYAYSPQLEGCQSQGDTLEEVKRNIQEAIELYLSTLSEVEKHNLLNREIVTMSIEVNVA
>NC_011726.1|WP_012594986.1|1744613_1747631_-|N-6-DNA-methylase
MSKLLISQYHSEVEKIIQYGGSRKETSIRVAFQNLLNEYCKLRDFLLIPELDYQTKSGNVVYPDGTVKDALRLDWGYWESKDQYDNLDVEIEKKLSKGYPNDNILFEDSQQVVLIQGGEEKLRVSVRDVEGLDTVLNAFINYVRPEVKDFREAIESFTEDLPTIVEALRELIAKQSEENKRFIEARNKFLKICQDSINPEISLLDVREMIIQHILTEDIFINIFNESQFHRENNIARELQGVIDTFFTGTTKRNTLGTIERYYAVIRRTAASIYNHQEKQKFLKSVYENFYKAYNPKAADRLGIVYTPNEIVRFMIESVDYLVHKHFGKLLCDPGVEILDPATGTGTFITELIEYLPKDKLKYKYQNEIHCNEVAILPYYIANLNIEYTYKQKMGEYEEFDHICFVDTLDNTSFTGKQLDLFAMTVENTQRIKDQNDRQISVIIGNPPYNAKQENFNQNNANRKYTEIDKLIKDTYIKQGTAQNKNVVYDMYTRFIRWASDRLNKDGIIAFITNSSFLDALAFDGFRKSIKDEFSYAYFIDCGGNVRAISGKDGIFICEKHTIFGTAAMTGIAILFLVKDSQATGNKIFYANPFHVHELRENKLSYLQQNSISKISFEHIHPNKKNNWLNQANNDFDDLLPLMDKEVKAGKSTEAIFKLFSSGLKTHRDEWVYDFSQDELEKKMKFFINTYQKTLEDNDYTEKDLIKWDADLKQYLKRNISKEFDNQNIVESLYRPYIKEFLYFDKHFNGRTYQWFNLYQTENKNYYICLSGVGGSKPFQNLVTYYITCLDCLEKTQCLPLYTYDEEGNRIDNITDWGLEQIQTHYQDKSITKLDIFHYTYGVLHNPEYRQKYELNLKREFPHLPLYENFFQWVEWGQKLMDLHINYETVEPYPLNRIDIPLKNENATPKPKLKADKPKGIIIIDDITQLQNIPAIAWDYKLGNRCALEWILDQYKEKKPKDQTIAEKFNNYRFSDYKEIVIDLLQKVCCVSVETMKIIEEMERK
>NC_011726.1|WP_012594987.1|1748041_1748653_-|Uma2-family-endonuclease
MVQLLPKLITFDEFIEWLPETRRYELHEGTIIEMQPTGKHEDIAGFLTQELTLEYTRMNLPYRIPPKALVKLKDKETGYNPDLLLIDRRKLVNEPFWDKKSTLINGESIALVIEIVSNNWRDDYGYKLIDYEAMGIREYWIVDYLGIGGVRFIGQPKQPTISLYQLIDGEYQVKQFRGQESINQSLIFPDLNLTAEQIFKAQR
>NC_011726.1|WP_012594988.1|1748670_1749831_-|lipid-A-disaccharide-synthase
MRIFISTGEVSGDLQGSLLVESLYQRAEARGIPLEILALGGDRMAAAGAKLLGNTAAIGSIGIVESLPFIIPTWLMQRRVKQYLRENPPDILILIDYMGPNAAFGQYARKHLPQVPIIYYIAPQSWVWAPNSKTIQQFAHITDLLLAIFPEEARFFEEKGVSVKWVGHPLLDRMAKAPSREVARQRLNLHSDQLIVALFPASRYQELKFHLPLMCQAAAKLQEKIPNLHFLLPVSLSEYRSTIEETVKAYPFSVTLLDGQALDVMAAADFAIAKSGTVNLELALLKIPQLVLCLVNPLTMWIARNILKFSIPYMSPPNLVVMEAIIPELLQEEATIERIVQESLDLLLNTERRQKTLADYEQMSTLLGEVGVCDRVANEILDYSKS
>NC_011726.1|WP_012594989.1|1749853_1750684_-|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase
MLTDQSKRDALLNTHIHPTAVIHPKAELHPTVTVGPYAVIGENVKIGAQTTIGAHAVIEGPIEIGIGNRIFPSAVIGLEPQDLKYKGAASWVKIGDYNTIREFVTINRATHADEVTEIGSHNLLMAYVHVAHNCVIEDHVIIANAVALAGHVHIESRAVIGGALGVHQFVRIGRNAMLGGMSRIDRDAPPYMAVEGNPSRVRALNLIGLKRAGLTAEDLSSLKKAFRLLYRSQLTFKEALEELQALSNNQYVEYLYQFLQASTTGEKRRGPIPGKN

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Crispr_ID: NC_011726_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_6

2283960-2284149

TypeV-U5

V-U5

Consensus_repeat	Method
AAACTTTCAACCTACCCCTTATCGGGATGGCGGTTGAAACCCAT	PILER-CR

2 spacers

c2c5_V-U5

The CRISPR arrays of NC_011726_6

>merge|NC_011726|6|2283960-2284149|PILER-CR
CTTTCAACCTACCCCTTATCGGGATGGCGGTTGAAACAGTCATTTTCATTGAGTCACGCAATTACGCCCGCCAAACTTTCAACCTACCCCTTATCGGGATGGCGGTTGAAACCCATCCCAGTTAATAGAGTTGGGTGCACAGCGTAAAACTTTCAACCTACCCCTTATCGGGATGGCGGTTGAAACCCCT

>NC_011726|6|4|2283960-2284149|PILER-CR
CTTTCAACCTACCCCTTATCGGGATGGCGGTTGAAACAGTCATT	TTCATTGAGTCACGCAATTACGCCCGCCAAACTTT
CAACCTACCCCTTATCGGGATGGCGGTTGAAACCCATCCCAGTT	AATAGAGTTGGGTGCACAGCGTAAAACTTT
CAACCTACCCCTTATCGGGATGGCGGTTGAAACCCCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_012595503.1\|2281325_2283509_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|366703
NC_011726.1\|WP_012595508.1\|2289151_2289370_+\|2-oxoisovalerate-dehydrogenase-E1-subunit-beta	unknown	unknown	unknown
NC_011726.1\|WP_012595496.1\|2273699_2274350_-\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|368559
NC_011726.1\|WP_012595507.1\|2288707_2289076_+\|endonuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|238509
NC_011726.1\|WP_012595497.1\|2274475_2276893_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226800
NC_011726.1\|WP_012595504.1\|2284683_2286522_-\|hypothetical-protein	c2c5_V-U5	-	unknown
NC_011726.1\|WP_012595501.1\|2280406_2280865_+\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl\|CDD\|349967
NC_011726.1\|WP_012595510.1\|2289666_2291040_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341176
NC_011726.1\|WP_012595500.1\|2279069_2280212_+\|glutamate--cysteine-ligase	unknown	unknown	gnl\|CDD\|131103
NC_011726.1\|WP_012595499.1\|2278398_2278866_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012595506.1\|2287036_2288605_+\|SAM-dependent-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|223363
NC_011726.1\|WP_012595505.1\|2286590_2287022_+\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133380
NC_011726.1\|WP_012595498.1\|2277056_2278343_-\|dihydroorotase	unknown	unknown	gnl\|CDD\|236002
NC_011726.1\|WP_012595512.1\|2291343_2291595_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012595511.1\|2291046_2291307_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012595502.1\|2280868_2281060_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012595495.1\|2272622_2273609_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021
NC_011726.1\|WP_012595509.1\|2289366_2289606_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NC_011726.1\|WP_012595494.1\|2271763_2272417_+\|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|234604
NC_011726.1\|WP_012595513.1\|2291581_2292007_+\|putative-toxin-antitoxin-system-toxin-component,-PIN-family	unknown	unknown	gnl\|CDD\|224485

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_012595503.1\|2281325_2283509_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.58639e-51
NC_011726.1\|WP_012595496.1\|2273699_2274350_-\|Uma2-family-endonuclease	gnl\|CDD\|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	4.55215e-14
NC_011726.1\|WP_012595495.1\|2272622_2273609_-\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	0.0060412
NC_011726.1\|WP_012595497.1\|2274475_2276893_-\|hypothetical-protein	gnl\|CDD\|226800	COG4354, COG4354, Predicted bile acid beta-glucosidase [Carbohydrate transport and metabolism].	0
NC_011726.1\|WP_012595501.1\|2280406_2280865_+\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl\|CDD\|349967	cd18094, SpoU-like_TrmL, SAM-dependent tRNA methylase related to TrmL. tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	5.52904e-83
NC_011726.1\|WP_012595510.1\|2289666_2291040_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341176	cd17287, RMtype1_S_EcoN10ORF171P_TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit TRD-CR, similar to Escherichia coli N10-0505 S subunit (S.EcoN10ORF171P) TRD2-CR2, and Herpetosiphon aurantiacus S subunit (S.HauORF5277P) TRD2-CR2. The recognition sequences of Escherichia coli N10-0505 S subunit (S.EcoN10ORF171P) and Herpetosiphon aurantiacus S subunit (S.HauORF5277P) are undetermined. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one heteromeric enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	6.7554e-98
NC_011726.1\|WP_012595500.1\|2279069_2280212_+\|glutamate--cysteine-ligase	gnl\|CDD\|131103	TIGR02048, gshA_cyano, glutamate--cysteine ligase, cyanobacterial, putative. This family consists of proteins believed (see Copley SD, Dhillon JK, 2002) to be the glutamate--cysteine ligases of several cyanobacteria, which are known to make glutathione. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	0
NC_011726.1\|WP_012595506.1\|2287036_2288605_+\|SAM-dependent-DNA-methyltransferase	gnl\|CDD\|223363	COG0286, HsdM, Type I restriction-modification system methyltransferase subunit [Defense mechanisms].	5.67916e-100
NC_011726.1\|WP_012595505.1\|2286590_2287022_+\|MerR-family-transcriptional-regulator	gnl\|CDD\|133380	cd01105, HTH_GlnR-like, Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators. Helix-turn-helix (HTH) transcription regulator GlnR and related proteins, N-terminal domain. The GlnR and TnrA (also known as ScgR) proteins have been shown to regulate expression of glutamine synthetase as well as several genes involved in nitrogen metabolism. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	2.20686e-18
NC_011726.1\|WP_012595498.1\|2277056_2278343_-\|dihydroorotase	gnl\|CDD\|236002	PRK07369, PRK07369, dihydroorotase; Provisional.	0
NC_011726.1\|WP_012595509.1\|2289366_2289606_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	7.24441e-12
NC_011726.1\|WP_012595507.1\|2288707_2289076_+\|endonuclease-domain-containing-protein	gnl\|CDD\|238509	cd01038, Endonuclease_DUF559, Domain of unknown function, appears to be related to a diverse group of endonucleases.	9.1138e-42
NC_011726.1\|WP_012595494.1\|2271763_2272417_+\|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl\|CDD\|234604	PRK00058, PRK00058, peptide-methionine (S)-S-oxide reductase MsrA.	2.3e-161
NC_011726.1\|WP_012595513.1\|2291581_2292007_+\|putative-toxin-antitoxin-system-toxin-component,-PIN-family	gnl\|CDD\|224485	COG1569, COG1569, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	8.04021e-32

>NC_011726.1|WP_012595503.1|2281325_2283509_+|peptidoglycan-DD-metalloendopeptidase-family-protein
MSSCLADTANASVIPLTEDSPSNIAPNDSTCRVRRSAAMIGLAISMSATGLLLTQNKAAVAANSLAENVNLSSLPAPSYPQLAKADTVESEDGKLAPVSLKHKVKAGESIEELGRIYQVDSKAIASINNLPLQAPLVPGQTLKIPSVSKLDSGSQAPQVKIETSKSQELASKPLNTSLDHLRETRKRLQESLVELKTEKSKAEVTPLVADVSDVSQPLNAQETPSSVNQEGQGISIPVIQPENNSVSRQISPSSSTLTSTEGETPTIKPASKVPSLAKLPSVPQAKIEESELPQFNEPIAIPVLPAENNSEVPSVSSPRRLSTLPQPREVAPQTTPPTHQARIVPQPSFNEPVSNRFYRVRPGDTLNSIARSHGLTLSELIRANGITNPNLIKVHQNLIIPQKGLSARSQLQPRNLANLPQSGNLVASSPDGLSPSALPVPLSPLPSRATTETNEFQKRYSGQKQSEPIEIEVTSAFDSHTDKLKADIANLEQEYADNSESDAIEIQTELENERTKPIVGQTLNNEWARDRQGRTFSDRQKQPGDRRIAQRLPNSRLVGVAPSDTEQYNDAFRIPVGTNVGPELPPLSGPDNYLPGAPTQFTGYIWPTKGVLTSGYGRRWGRMHKGIDIAAPIGTPIIAAAPGEVITSGWNSGGYGKLVKVRHPDGSVTLYAHNSRLLVRRGQQVEQGQQIAEMGSTGYSTGPHLHFEVHPNGRGAVNPIAMLPRKN
>NC_011726.1|WP_012595502.1|2280868_2281060_-|hypothetical-protein
MRVRRRSGVAESFRDRLSLWINRAFPQGIIDMTEPRKWLITAQKCTILVALIEPNNDRNSLLV
>NC_011726.1|WP_012595501.1|2280406_2280865_+|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MLKIVLVHPQIPPNTGNIARTCAATETELHLVGPLGFELSDRYLKRAGLDYWPYVNLHYHKDLAEFYSVYQQHTGRLIGFSVRGQSPYHQWTFQENDWLLFGSETEGLPKSVLENCDATLYIPMSQSKVRSLNLSVSVTIGLFEARRQLSIF
>NC_011726.1|WP_012595500.1|2279069_2280212_+|glutamate--cysteine-ligase
MRLSKGLEIEIYTGTADGQIIGLSDRIVKDLEGFVREPDARNVEYTTAPLCCYDRLLCAILRPRHDLRQYLTNIGNYTLIPGSTLSLGNSDRFYRSDPHNPYHSYIEQTYGTNVVTASIHINIGISDPEILMQACRLVRLEAPLYLALSASSPFLDGQVTGYHSTRWHLFPQTPDHVPLFTSHAHFIQWTEEQLALKTMQNVRHLWTSVRPNGDNRPYNVNRLELRICDLVVEPIALLSIVALLEARLSQLINDLSLDPLTQSQLSPEELLKITAQNERAVAKDSLKAQLNHWQDGREIWVQDWIEELYQDVWLTAKQGGFSCFLSPLKKLLREGNLAQQWLRKYESGQDIPSILVDEIEAMTQRESDLADKLCDARLVA
>NC_011726.1|WP_012595499.1|2278398_2278866_-|hypothetical-protein
MRQTLLLIYLSYFCLSYPAFSQSNQPILDGTINQEETSSPASNPPLNSNISLIMGMWRGFHEIEETTLYYGYQFRPNGTFSARHRLYEGEKTLEDNLLQGQWTFDGQIVQITGNSSNNPEQSLKIQFRLSEDLHLYYQTGSLPDTYSLMRLGKVQ
>NC_011726.1|WP_012595498.1|2277056_2278343_-|dihydroorotase
MNTSTVFRQVRVLDPFANTDMIADVWLNDGKIQAIDPHLNVISPETTIIEAQGLILGTGLVDLYSYSGEPGFEDRETLTSLAAAAIAGGFTRVAILPQTKPGVDNAATFSFLQQKAQTLPNSPHLHFWGNLTLGGQGKQMTELAELAMAGVVGFTDGQSIENLGLLRRILEYLKPLEKPVALVPESSSLKGNGVMREGLLSIHYGLPGNPAIAESSAIATILEIVAEINTPVHLMGISTRRGVELMASAKARGLPITASTSWMHLLLDTHDISNYDPSLRLEPPLGNPEDRQALIEGVREGIIDAIAVNHRSLTYEEKTVAFAEAPTGAIGLELALPLLWDQLVVQGEWSPLQLWKALSCYPCQCLGLEVAGLQVGQPAELILFDPQKTWQVDGTTLQCLGRNTPWYQQEIKGRVITSFVGKENNTLT
>NC_011726.1|WP_012595497.1|2274475_2276893_-|hypothetical-protein
MKTLFSLPNIPPCAWKRPIGQGWDKPYTVRYASNLDDGPNHGMPLGGFGSGCIGRSPSGDFNLWHLDGGEHVFRSIPSCQFSVFEQPEGEDAQVYALSTQPPEEGTLSRWSWYPPEKGTYHALYPRSWYQYEGVFKSQLICEQFSPIIPNNYQETSYPIGIFEWTAHNPTDKPITLSIMVTWQNIVGWFTNAIKSPEITVRDDGSPEYQYQPRWGDSTGNFNQWVQDNFRVGFILNRIQLHDEIQEGEGQICIASVTNPSVEVFYLGKWNPKGDGSEVWDYFAMNGSLPDTEDETPAEPGEQIAVAMAIRFTIRPGRTKKIPFILAWDFPVTEFAPGVQYYRRYTDFYGRNGKNGWAMVRTALKHSDVWYERVEEWQSPILKREDLPDWFKMALFNELYLLTDGGTLWTAASENDPVGQFGVLECLDYRWYESLDVRLYGSFGLMMLWPRLEKSVLEAFARAIPTHDDTPRIIGYNQAKAIRKAKGATPHDLGAPNEHPWQKTNYTSYQDCNLWKDLGSDFVLQVYRDYLLTGSDDTDFLWECWPAITETLDYLKTFDLDNDGIPENSGAPDQTFDDWKLQGISAYCGGLWIAALEAAIKIAEILLKNVPTTEELQSRNNPESIKHYVKNHRDWLEQSRSIYHDTLWNGEYYKLDSQSGSDVVMADQLCGQFYARLLNFPDVVETQYTESALNKVYEACFLKFQDGKYGAANGMKPDGTPEDPNSTHPQEVWTGINFGLAAFLLQMGRKDAAFKLTEAVVKQVYENGLQFRTPEAITAVGTFRASHYLRAMAIWGIYGILTHFRP
>NC_011726.1|WP_012595496.1|2273699_2274350_-|Uma2-family-endonuclease
MFITVNQNTLTLTPGSEIILQYQTWDDYENLLEIRQEKPLPKIYFHAKTNTIRLMSPLPSHGNRVDILRDLVKSLLGKQGKDWHCFDPITLKHFKQAGVEPDTCFYIDHRDAILGKEKLDLSVDPPPDLAIEVDFTSLTDIEAYQTLKIPELWIYRQSILKIYRLVGENYQESSTSGIFANVNVKEILPKYVELAWNQGSSVALRQFEQEYLNKIN
>NC_011726.1|WP_012595495.1|2272622_2273609_-|hypothetical-protein
MSSPKLPPTTFRVRNFLAGLKPLGSLVFLAPVVTVALLAVGLWQYRLHPEWLGNITSPVGTIEGEVGNNLDIGINPQNVEGNTPITNPQSSLPPQENNLDIPLPSPLGLADPQIPVAPQNLPELPPASNAANPPSSPNKQQLPQIFQPLLPHVKNPNSLSPSLSGSGNTSQPVNIPNLKPIEIAPIQTNPLYNAMQQNALPSGITPPSNPLGNTSVNPSPSSINQPTPTGFNQVPTQPQYSQVPRQSMVPSYQAYPGNPNGYSTPYNQSVGGGYPNGYGVPTTPVQPVQPINPYGYGTPQGYNQPTAPQNNYGMQRPQISGSDSVYSR
>NC_011726.1|WP_012595494.1|2271763_2272417_+|peptide-methionine-(S)-S-oxide-reductase-MsrA
MALFGFGKKLTLPTPETALPGRRQAMPVPASHYVNGHPLKPPFPSGLETAMFGLGCFWGAERKFWQCEGVYTTAVGYAAGITPNPTYQEVCTGLTGHNEVVLVVFDPKIISYEELLKVFWESHNPTQGMRQGNDVGTQYRSGIYVYSPQHKKAAETSKEVYQKALNQAGYGDITTEILDAPEFYYAEDYHQQYLAKNPNGYCGLGGTNVSCPIGLNV
>NC_011726.1|WP_012595504.1|2284683_2286522_-|hypothetical-protein
MSQITIQCRLVAKEPIRHTLWQLMADLNTPFINELLQKVAQNPDFEQWKQKGKLQKSVIKQLGDKLKKDPRYLGQPARFYTSGISLVEYIFKSWLKLQQRLQRKLDGKRRWLTVLKSDEELIQQSQQNLEAIRHKASEILQTHQKTEKLFNHLFQLYQEEKNPFTHIALCYLLKNRCKLPQKPEDPEKFTKRRRKVEIAIDRLQEQLEGRLPQGRDLTNHNWLETLSIACQTDPEDTAQARSWQDKLLIQSQSIPFPINYETNEDLTWHKNEKGRLCVKFNGISDLSFEIYCDQRQLKWFQRFYEDQQAKKGSKNQHSSALFTLRSGRILWQEGNEKGQPWNIHRLILQCTLDTRLWTQEGTEEVKQEKAEEIAKVLTSMNEKGDLTKNQQAFIKRKQSTLDKLENPFPRPSQPLYRGQSNILVGVSMGVDKPATVAVVDGITQKTLTIEYIKQLLGNNYPLIQRQRQQKQHQSHQRNVAQRKEAFNQFGDSELGEYIDRLLTKAIVTLAKKYKAGSIVVPKLEDMREIVQTEIQTKAEERIPNCIEAQKNYAKCYRVQVHQWSYSRLIDNIEAQASKLGIVLEISQQPYKGTPHDKAIALALNAYQSRLSA
>NC_011726.1|WP_012595505.1|2286590_2287022_+|MerR-family-transcriptional-regulator
MGETFFTSKDAAKITGCTLRQLQYWREKGVIVPMVSATGTGRSVYYSRSELVELAVMVYLLSVGLTFESASGVLQQLRELEPNFAKENSQRRLMLVFDTSEGILKLKDFERESAIAFLDRGEAIIPLWLEQIHQQLNQTLPIN
>NC_011726.1|WP_012595506.1|2287036_2288605_+|SAM-dependent-DNA-methyltransferase
MAKQNGKTVQNNSNSDKSLESWIWDAACSIRGAQEAAKYKDFILPLIFTKRLCDVFDDELNRIAVKVKTREKAFKLVEMDQNLVRFYLPLKPDNPDDAVWSVIRQLSDKIGETLTGYLRDIAKANPLLKGIIDRVDFNATIHGERELDDDRLSNLIEKISEKRLGLKDVEPDIIGRSYEYLIRKFAESGKSAGEFYTPKEVGIIMAKIMQPQPGMAIYDPCCGSAGLLIKCQLVLAESQEKGEKYAPLQLYGQEYTGDTWAMANMNMIIHDMEGKIEIGDSFRFPKFKQGGNLAQFDRVVANPMWNQNWFTEQDYDGDEWGRFPQGAGFPGSKADWGWVQHIWASLQLHGQSAIVLDTGAASRGSGNANKDKEKEVRKWFVEKDIIEGVIYLPENLFYNTSAPGIILILNKAKSEARKHQLLLINASLEFAKGDPKNYISDQGINRIVTAFLNWEEQDKFSRIVSLEEIAKNDYNISPSRYIHVTEAEEFRPIGEILQELEELESQAEETNRVLMQVLSKFR
>NC_011726.1|WP_012595507.1|2288707_2289076_+|endonuclease-domain-containing-protein
MKDTPRIRGTTPEIEAAARRLRCNLTPAEAYLWEALRGKKLKGLKFRCQHPVGRFILDFYCPSCKLAIEIDGSSHDTKQEYDQVRTEKLAQYGYRVLRFTNEEVMTDLSRVLAEIEKVAFTP
>NC_011726.1|WP_012595508.1|2289151_2289370_+|2-oxoisovalerate-dehydrogenase-E1-subunit-beta
MSQSTEIVFLVEDAPEGGYTARALSESIFTEADDLESLREMVKDAVHCHYDNVESRPKIIRLHIVRDEVFAS
>NC_011726.1|WP_012595509.1|2289366_2289606_+|type-II-toxin-antitoxin-system-HicA-family-toxin
MKLPRDLSSDDFIKKLSRLGYEVTRQTGSHIRLTTQENGEHNITIPAHNPVKIGTLNAILRDIAQHFSLSRDELLKRLF
>NC_011726.1|WP_012595510.1|2289666_2291040_+|restriction-endonuclease-subunit-S
MNKSKNTQLELNLCLEDENSGHENKILARDFPPEWQLIPLKNAVTYIDYGYSHSIPKIPPENGIKIVSTADISKTGELLYSQIRKVEAPLKTIQRLTLHDGDVLFNWRNSSYLIGKTTIFEEQSEPHIFASFVLRLKCDEIKSHNYFFKYLLNYYRYSGIFESLARRAVNQANFNKNEVSDLIIPLPPIEEQRKIASVLTLIQEAIQEQENAIALTTELKKALMQKLFTEGINNEPQKMTEIGLIPESWEVVNLGNLAKLKSGGTPSRKKIEYWENGSIPWVKTTEINYDLITTTEEYITKEGLVNSSAKMFSKGTLLMAMYGQGVTRGRVGILDIDATTNQACVAIMPNSEDKLSTKFLYHYFSYHYEKLRNQGHGANQSNLSSTILKMFPITFPKIQEQLIIINHFDTLNLKLEQSHKRITILQDLFSTLLHQLMTAQIRVDELELSVLEKQIKE
>NC_011726.1|WP_012595511.1|2291046_2291307_+|hypothetical-protein
MNPSTYTPETLIESIKQLPQESLPELAQFVEYLHYKNQQQNLTHESSITLEQTEQLTEELLTEMGDNLPSLSDYAISRTGIYEEHP
>NC_011726.1|WP_012595512.1|2291343_2291595_+|hypothetical-protein
MINQEEITIKVSPELAQAYRQASQETQEQIGLKVNAVLSLELENRRKEAVKKLSILMDKASEEAQANGLTPEILEEILANEET
>NC_011726.1|WP_012595513.1|2291581_2292007_+|putative-toxin-antitoxin-system-toxin-component,-PIN-family
MKKLKFVLDTNIIISAFLFQNSKPRQALELAKNHHLILLSTNIIQEMRTVIQRPKFDRYISLSLREELLDTLIESSLMIDPDEIVTECRDPKDNKYLELAITGQAKCIITGDEDLLILNPFREIPIMTVQEFLTTYEEVTE

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Crispr_ID: NC_011726_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_7

2521799-2521867

Orphan

Consensus_repeat	Method
AATTTACAAGGGGCTGATTTAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011726_7

>merge|NC_011726|7|2521799-2521867|CRISPRCasFinder
AATTTACAAGGGGCTGATTTAACAGGAGCCAGTTTAATTAAAGCTAAATTGATGGGGGCTAATTTAAAA

>NC_011726|7|6|2521799-2521867|CRISPRCasFinder
AATTTACAAGGGGCTGATTTAACA	GGAGCCAGTTTAATTAAAGCT
AAATTGATGGGGGCTAATTTAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_012595713.1\|2513980_2514994_+\|DUF2235-domain-containing-protein	unknown	unknown	gnl\|CDD\|370774
NC_011726.1\|WP_049769529.1\|2511680_2513807_+\|acylase	unknown	unknown	gnl\|CDD\|376618
NC_011726.1\|WP_012595721.1\|2524851_2526306_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012595715.1\|2516944_2518951_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366443
NC_011726.1\|WP_012595719.1\|2521997_2523176_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|226925
NC_011726.1\|WP_012595720.1\|2523204_2524845_-\|phospholipid-carrier-dependent-glycosyltransferase	unknown	unknown	gnl\|CDD\|227621
NC_011726.1\|WP_012595723.1\|2529554_2530328_+\|hydroxyacylglutathione-hydrolase	unknown	unknown	gnl\|CDD\|274569
NC_011726.1\|WP_012595722.1\|2526328_2529433_-\|alpha-mannosidase	unknown	unknown	gnl\|CDD\|223460
NC_011726.1\|WP_012595714.1\|2515038_2516769_+\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
NC_011726.1\|WP_012595717.1\|2519284_2519476_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012595724.1\|2530333_2531143_+\|ion-transporter	unknown	unknown	gnl\|CDD\|366146
NC_011726.1\|WP_012595707.1\|2507848_2508061_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|212463
NC_011726.1\|WP_012595726.1\|2532036_2533068_+\|cobalamin-biosynthesis-protein-CobW	unknown	unknown	gnl\|CDD\|274151
NC_011726.1\|WP_012595727.1\|2533588_2534140_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NC_011726.1\|WP_012595708.1\|2508128_2508800_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|381154
NC_011726.1\|WP_012595728.1\|2534491_2534743_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012595716.1\|2519046_2519313_+\|BrnT-family-toxin	unknown	unknown	gnl\|CDD\|367913
NC_011726.1\|WP_012595725.1\|2531217_2531985_+\|Uma2-family-endonuclease	unknown	unknown	gnl\|CDD\|99749
NC_011726.1\|WP_012595710.1\|2509087_2510419_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NC_011726.1\|WP_012595709.1\|2508831_2509041_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_012595713.1\|2513980_2514994_+\|DUF2235-domain-containing-protein	gnl\|CDD\|370774	pfam09994, DUF2235, Uncharacterized alpha/beta hydrolase domain (DUF2235). This domain, found in various hypothetical bacterial proteins, has no known function.	1.95058e-112
NC_011726.1\|WP_049769529.1\|2511680_2513807_+\|acylase	gnl\|CDD\|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	3.65183e-147
NC_011726.1\|WP_012595725.1\|2531217_2531985_+\|Uma2-family-endonuclease	gnl\|CDD\|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	1.69374e-18
NC_011726.1\|WP_012595715.1\|2516944_2518951_+\|hypothetical-protein	gnl\|CDD\|366443	pfam01060, TTR-52, Transthyretin-like family. TTR-52 was called family 2 in, and has weak similarity to transthyretin (formerly called pre-albumin) which transports thyroid hormones. The specific function of this protein is as a bridging molecule in apoptosis cross-linking dying cells to phagocytes. TTR-52 bridges by cross-linking surface-exposed phosphatidylserine (PtdSer) on apoptotic cells to the CED-1 receptor, a transmembrane receptor, on phagocytes. TTR-52 has an open beta-barrel-like structure.	3.42428e-05
NC_011726.1\|WP_012595719.1\|2521997_2523176_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|226925	COG4552, Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only].	6.48006e-98
NC_011726.1\|WP_012595720.1\|2523204_2524845_-\|phospholipid-carrier-dependent-glycosyltransferase	gnl\|CDD\|227621	COG5305, COG5305, Predicted membrane protein [Function unknown].	1.4984e-45
NC_011726.1\|WP_012595723.1\|2529554_2530328_+\|hydroxyacylglutathione-hydrolase	gnl\|CDD\|274569	TIGR03413, GSH_gloB, hydroxyacylglutathione hydrolase. Members of this protein family are hydroxyacylglutathione hydrolase, a detoxification enzyme known as glyoxalase II. It follows lactoylglutathione lyase, or glyoxalase I, and acts to remove the toxic metabolite methylglyoxal and related compounds. This protein belongs to the broader metallo-beta-lactamase family (pfam00753). [Cellular processes, Detoxification].	1.02008e-136
NC_011726.1\|WP_012595714.1\|2515038_2516769_+\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	5.05941e-37
NC_011726.1\|WP_012595724.1\|2530333_2531143_+\|ion-transporter	gnl\|CDD\|366146	pfam00520, Ion_trans, Ion transport protein. This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.	1.18953e-19
NC_011726.1\|WP_012595707.1\|2507848_2508061_+\|hypothetical-protein	gnl\|CDD\|212463	cd01716, Hfq, bacterial Hfq-like. Hfq, an abundant, ubiquitous RNA-binding protein, functions as a pleiotropic regulator of RNA metabolism in prokaryotes, required for transcription of some transcripts and degradation of others. Hfq binds small RNA molecules called riboregulators that modulate the stability or translation efficiency of RNA transcripts. Hfq binds preferentially to unstructured A/U-rich RNA sequences and is similar to the eukaryotic Sm proteins in both sequence and structure. Hfq forms a homo-hexameric ring similar to the heptameric ring of the Sm proteins.	4.17947e-08
NC_011726.1\|WP_012595726.1\|2532036_2533068_+\|cobalamin-biosynthesis-protein-CobW	gnl\|CDD\|274151	TIGR02475, Probable_cobalamine_biosynthesis_protein, cobalamin biosynthesis protein CobW. The family of proteins identified by this model is generally found proximal to the trimeric cobaltochelatase subunit CobN which is essential for vitamin B12 (cobalamin) biosynthesis. The protein contains an P-loop nucleotide-binding loop in the N-terminal domain and a histidine-rich region in the C-terminal portion suggesting a role in metal binding, possibly as an intermediary between the cobalt transport and chelation systems. A broader CobW family is delineated by two Pfam models which identify the N- and C-terminal domains (pfam02492 and pfam07683). [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	1.75289e-164
NC_011726.1\|WP_012595727.1\|2533588_2534140_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	2.00669e-44
NC_011726.1\|WP_012595708.1\|2508128_2508800_+\|response-regulator-transcription-factor	gnl\|CDD\|381154	cd19927, REC_Ycf29, phosphoacceptor receiver (REC) domain of probable transcriptional regulator Ycf29. Ycf29 is a probable response regulator of a two-component system (TCS), typically consisting a sensor and a response regulator, that functions in adaptation to changing environments. Processes regulated by TCSs in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Ycf29 contains an N-terminal REC domain and a LuxR-type helix-turn-helix DNA-binding output domain. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	7.1187e-50
NC_011726.1\|WP_012595716.1\|2519046_2519313_+\|BrnT-family-toxin	gnl\|CDD\|367913	pfam04365, BrnT_toxin, Ribonuclease toxin, BrnT, of type II toxin-antitoxin system. BrnT is a ribonuclease toxin of a type II toxin-antitoxin system that exhibits a RelE-like fold. The antitoxin that neutralizes this toxin is pfam14384. BrnT is found in bacteria, archaea, bacteriophage, and plasmids. BrnT-BrnA forms a 2:2 tetrameric complex and autoregulates its own expression, which is induced by a number of different environmental stresses. Expression of BrnT alone results in cessation of bacterial growth which can be rescued after subsequent expression of BrnA.	3.04183e-30
NC_011726.1\|WP_012595710.1\|2509087_2510419_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	7.34877e-143
NC_011726.1\|WP_012595722.1\|2526328_2529433_-\|alpha-mannosidase	gnl\|CDD\|223460	COG0383, AMS1, Alpha-mannosidase [Carbohydrate transport and metabolism].	0

>NC_011726.1|WP_012595717.1|2519284_2519476_+|hypothetical-protein
MNDNNITRVKLDPKNPTQGKTNWVKVKAMTEEEIEQAAKNDSDCLPLSQKELNEFRRIMEKSD
>NC_011726.1|WP_012595716.1|2519046_2519313_+|BrnT-family-toxin
MEIEWNNDKAASNVIKHNIDFEDAKNIFLAPNRLEREDKRNYNETRIQVIGIVNQVVLFVVYPKRENRYRIISARRANKNERQQYYQS
>NC_011726.1|WP_012595715.1|2516944_2518951_+|hypothetical-protein
MSTKTKTIFDEIKAALVLKVIDSPLGRKLIEEKAEKQVSKTQEAITKPIEQLNKATGQLLFSDTNKPLHNIELEVWDRDVGTPSDYLGKGVTDQNGRFEIYYDPEKAGFKDAPDLELRVIDNRVTFDSDNQPVYTNRIAYIIKGGDNVTQKTYDFGTLTVPYWPYDPNSPFARIFMPNPEETPDDYSVGRKFQAYASANVLTPIKAKHTIANTLNPKEPSLTQIQADYPPNLTINLDREKPGYTRSDEYFVLRVLNGMNPCLLKRSKSDPNQFKMSFIWDNYEKDTEHDLHNVEAYFVLKDGKLFPTMITIQSRYPDSLAPHSPLKDREVYTPNDGEKWLQAKRIFRTAALFDGEAIEHYAKAHVQMEQYAVACFRNLRKNPIRLMLTPHLKSIININRRGDDLLVEPNLGLFVTNGPLTYPGFLQMCTEVVATYDWKDWQPRQPICDDHKYAKAANLYWQILTEYVDAFFAKHQQAIADEWVEIRRFSEDLVEHSMPYQPIEGIMANTDSDYEWYDTGELDKPDLPRATFNGKTKVIRPITNSNQPSATDIDNLKQCCRHIIFHTTLWHTWVNDSQSDEGGELAYNSLALRNGSFGSETDPNIAPDPIEATNQVYIFSVLNGIKYGLLVKNEDDDVPEELRTALLNRKDQFAELGIDIGNIRTLINI
>NC_011726.1|WP_012595714.1|2515038_2516769_+|cytochrome-P450
MFKGLKIALQADTGRWFTRCNNCQQTIGNNPDTVTVHVEGSVSEHPYAQFEVVDVGNGKIALKADTGKYVGRCNGCIVGGAYPDFLTIHVDDPSMPWAQFTPERLANGKYAFKADTGKYFGRCNGCSPTSAYPDTVAVHVDNPHNSPWAQWTVSYVPFSYLERYDAIPADNVAEKAKLVGRAMATDSRNFFKELRANRPIFITPKFVLVTLFPDVQEVFSRPEVFSVRLYAPKMDPNHGPAMLSRDNTVYNWREKSIMKTMLDWEDLPRIKQAAGEVAKAALDKFAPTKKIETVNELAKWVLVRMSGDYYGFPGPDRETMYRWSSATQSGMLRNLANDPQIHEASVQAGKEMRDYLTQLLQQKKANNTPSTAPKDIFTRLVQANLTSDIPFDESRILTNMALLLISTLDTTAQAIVQSLEQLLRRPDILPKAVAAAKANDDVTFAKYVWEALRFNPVSPALPRFCESDYTVAAGTSRATRIPANSLVLVSLGSAMMDGAIVQNPEQFSIERPKHNYMHYGYGDHTCLGEHIGNVVVSEVIKQVLLRPGVRLIPGDEGKLQAQPNAILKSFVIAYDG
>NC_011726.1|WP_012595713.1|2513980_2514994_+|DUF2235-domain-containing-protein
MKRLVVCCDGTWQDLESSYPSNVVKLTEAIKPIASDGTPQIVFYDAGIGTESQKISGGAAGVGIDRNIQDGYRFLCLNYVEGDEIYLFGFSRGAYTVRSLAGMIHCSGLLKRSYITDAAEAYELYRNRDIKPSDPEAVKYRKVHGDRVPITLVGCFDTVGALGLPVVPLFRMFKPWVHRRYQFYDTTLNPDVQNALHAVAIDEIREVFDVTPMTPNPKAENQRLIQKWFPGDHGCVGGGTEAYRGLSDAALTWMIDSIGDLGLGLDFDLSAIRTGIKLDCECNFSNKPGFYRLAGIKLREVGEALEDLHDTTIERLKNRPDYRPPNLEKVIPKIVQK
>NC_011726.1|WP_049769529.1|2511680_2513807_+|acylase
MLAALHLLPYPKPLNRFISLVLSSLIVIILLTFTMSSVGANQTEILWDTWGVPHLYAQDTKSLFKAFGWAQTKSHGNLILKLYGQARGKAAEYWGINYLESDQYVKTMGIPARAQEWYQQQSPEMREYLDYFATGINDYVAQHPDEIDDSVKLVLPITPTDILAHLQRVIHFHFVTNPQSVSSLQTIAPQGGSNGWVIAPEKSASNHSILLANPHLPWSDFYLWYEAHLNAPGVNSYGAALVGMPVLAIAFNDHLGWTVTLNPIDGADMYQLTLKDQGYLWDGEVKNFETKTETVKIRQANGSYTELQFGVKRSIHGIIIAQEKNKAFALRVVGLDHPHGLKQLWEMAKSTNLEQFEKGLKQLQIPLFNFLYADQKGQIFYLFNGLIPKRPQGNWNDWQKIIPGDTSKTLWTEYHNYETLPRLVNPKTGWLQNTNDPPWTSTYPPILEAKDYPPYLAPPSLSYAPNILRSQRSITLLKDSKKLSFEDVINHKFSSRLLMADRLLEILIPTAKALANPIGIEAVKVLEKWDRQTNIDSRGAVLFTLWALTLESKGIFSRPWNPENPLETPAGLADINTALAVLEGVAAQVELLYGSLDIPWGEVVKMRFGDKSIPASGGPGKLGSFRVLNIQATADEKFQVVFGDSFIAVVEFSDPIRANVLNVYGNSNQPNSPHRGDQLSLYAEGKMRPVWRSKEEVKNHLILEELIR
>NC_011726.1|WP_012595710.1|2509087_2510419_-|HlyC/CorC-family-transporter
MSAIATEIIFILLLIIANGIFSGSEMAIVSSRKVRLEQLASRGNRQARTVLNLINAPNNFLSTVQIGITLIGILSGAIAGATLAERLTAIFQRIPLLKAYSQGISVGIVVGVITFLSLVMGELVPKRIALNAPEKIACAVAQPMKLLSRFAAPIVNLLSASTDFLLKLLGIKVSDEPAVTEEEIKVLIRQGADLGLFEESEHEMVERVFRLGDRSVKSLMTPRKEIVWLDIESPLAENLQEVIDSGYSRFPVGRGSLDQYMGVVRGNSLLAACLSNQEVDLESFLQQPLYIAENTRALNVLEQFKQTGIHTALVIDEYGGIEGLVTLDDVVEAILGELPSAEDLEAPMAVQREDGSWLLDGLLAIDDFKELFSDLPLPEISSQQYHTLGGFMMYSLKRIPQASEYFEWGRLRLEVVDMDGTRVDKVLVTVLDNAPEDEPINEE
>NC_011726.1|WP_012595709.1|2508831_2509041_+|hypothetical-protein
MTIWVNEQIDPCGIIYSCIACSDETAARECHQTWLNNLSDQQKQDGWTAILRTVNSWDEVPVNALKLSV
>NC_011726.1|WP_012595708.1|2508128_2508800_+|response-regulator-transcription-factor
MPLLILIADDDPGIRLAVKDYLELSGYSVITAQNGQEALSLLETYRPHLLVSDIKMPQKDGYTLVRHLRQLPEFRLLPVVFLTERGTKEERIQGYEVGCDVYLPKPFEMDELKAVIRNLVEKTQIIQSEWRFSQGESQPKPTLEPSQKEAIAVPSLLNSLHLTSRESQVLNLLARGLSNGEIGQNLHLSSRTVEKYVSSLLRKTETNNRAELVRFALDHHLID
>NC_011726.1|WP_012595707.1|2507848_2508061_+|hypothetical-protein
MAEFNTGLPSVRLVQQWIKDKKEVDVKLITNDLLVGIILWQDPQCIYLSEVSGQSTLIWRDSLVYLKPKG
>NC_011726.1|WP_012595719.1|2521997_2523176_-|GNAT-family-N-acetyltransferase
MTFSLNYSSLRHPEDEQQIKKLISQCFAEFLTESETYFNRIGSQNFRILHHNDQVIAGLAIYFMGQWYGENLIPMAGIAAVGVAPEHRGKGVAFQLLSHTLEELYHSGYPISVLYPATQVLYRKVGYEQGGSYCLWELPTDTIQISEKNLPITSISPINYEQFEAIYQQQARKNNGNLDRNFAIWQKTLEVQGKQESYAYLIGEKNQPEGYVIFTQEKGTNGLNLILKDWVLLTSDSVKHFWSFMAAHRSLASQVQWRSSPMDSTLLLLPEQTAKIKYQKRWMLRVVNVPLALSKRGYPQGIETELHLEITDDLIVANNGKFCLRVSQGCGEVTPGGKCNFRLNIRGLASLYTGLFTPIQLQLLGDLDATPDAIEAATIIFSGSTPWMPDFF
>NC_011726.1|WP_012595720.1|2523204_2524845_-|phospholipid-carrier-dependent-glycosyltransferase
MKISRLSIKLSFDFLIIFLICLSLVLGIFFRFYHLDKKFYSYDETHTSLRVSGYAASEMFSELASKNAAFDLVDFQKYQHPNSDKGTSQIISGLSKEDPHQAPIYFILARFWVQFFNHTLNNVAATRAFSAFLSVLALFLMYLLCQELFNSKKAALIAVALMAISPFHVLYGQYARPYSLFTVMVLLSSFLLLKVLKKKTLFNWILYTLACLFGFYTHIFMSLVIVSHFIYVLFLERFKLTRVFLSFIVSTLVTSTAGLLWLSTAISYNTKSGSIGNFRFWKLSQVIKMHLFRVSKVFVDTHNLGGIVRFESNSLLTTISQLLLVALLLVLIIYSLLYLIQKSDREQWLFVLSLIAVTGLLLGGIVRLIPNQMEARYYIPVYLGIQISIAYLLAQKINQKNNVFAMIFMTLIGLGIISCSISSQAQIWWVNLPSSIIQAPQVVQTVNAAKNPIIVWNDYQDVNGNWNTHVLLGWSYKLNPNVRFVYLNENSNLDQLLEDSNDLLLFKPQEEVQQKLSQKYNLEPAYQGESNPWLWTINLKQAKITN
>NC_011726.1|WP_012595721.1|2524851_2526306_-|hypothetical-protein
MQNIKMVLNRLPINQEQWNPKNFDILLIILGIILPFILVTFLDSYSRYDVGVFEDWASCWGQEIYLECPTTLVYPSGALIFSAGVIQGIKSLLSINDRHTVASVFRYFLAFFDSLNFLLWIYLAKMIHLRLAIVFAFIVLIIPSSWAGSSVWGQIEGISLFFCLASTIFFLKSWTKKQTNSHNKKAWKSGVWLLLGTPLLSIFILTKQWNIFSLPFFLLVFVVTVVQFWTNFGYRCIFWVLSALILLTLSFLYLDSFFLVVREFHHSSYWLIWTGPASNLIKKIAGNGFNIWIFLGRPRGSSSLVPFLTFNIGNWKSSLTPFKTGLFLYSMFIIFLLFTFYRNVLRVLQQNIMNKNLYQLNDYLIAILLFFHGLCHLGFNVLLSGTHERYLYLGYPSLLMAVIWFYTNKIVFSWHSTLLCFLAAFAYGCFVYSRIGNLPKFLILLQKHEFLGGIHFLLLGFLFYLWLQVCKNYKKTLHISPNLD
>NC_011726.1|WP_012595722.1|2526328_2529433_-|alpha-mannosidase
MILETIDQLRQLTQTDVQIGWVHTGDEIDFNSINLDAWEKGELNEKGYIIWPAGKQVKWLGQKFIIPDHLKGYPLAGLTLRLALTWWAEDAKIFVNNQLVQEGDLFDSSSRILLTSSVQPGEEILVLLRLVSPGHDIGGLMKSRLIYERESNLTVDDDFNTLVIDPGFVADELTILYNYLSAFEPEKLQILNQVINQINWKLVSDASKFDRCLLDLREKILPLANYIKQSSLNLLGHAHLDMAWLWPVNETWDAAQRTFTSVINLQKDFPILIFGHTSPVLYEWIENYRPDLFDKIIQAFKAGKWELLGGMWVEPDVNLVSGESLVRQLLYGQRYFNNKFGEISQVAWLPDSFGFCWQLPQILQQSGIKYFVTGKLHWNATVKFSHGFFKWESPDGTQLLTLVSPPNVAGVMDTNPIIMTNYAIDWAQQTGLKEAFWLPGVGDHGGGPTRDMLAVQKQWQKSPFFPQSQFSKAIDYLNKISHVTEEIPIWKDELYLDFHRGCYTTHADQKWFNRRSEDLLYKAELWSSITTIVLEKTNNCASKKLLEEAWKKVLFNQFHDILPGTSITEVFVQANEDWQQVQAIGQNILNESLEAIASQISLPQPPQANAIPLVVFNSLNWQRSQVVECSKAAENCQVYNLEGHLLTSQLSSENNLLFLAENIPSIGYRVFWLCPGKNLVNNVVLSYPQDYILENQYLKVIINSKTGDIDSIFDKVNQKEVIKGKANQLQIFQDQGQYWDAWNIDPNYNNYPLEGTQLKSIEYLEVGPIQWKIRVIRQFRKSEFCQDYILQIHSKLFKIKTQVNWQETHVLIKASFPLTIANNNTTYEIPFAAIERNNNPETPEEKAKWEVPALRWADISDPSQDYGVSLLNDCKYGYDSQCDRLRLTLLRSPRWPDPECDRGLHHFTYAIYPHQGNWKEAKTVQQGYELNIPLDLVYLPQVSTKSSHKLPSINYFLKFKSDNLILSAFKPSEDNASYWILRCYESEGKIAQMCLENNLNLQLTDSVNLLEEPLAEFSQVDPWKIVSFQGTIIK
>NC_011726.1|WP_012595723.1|2529554_2530328_+|hydroxyacylglutathione-hydrolase
MEIKRLPALSDNYIFLLYDADTQTAAVVDPAEPTPVLECLNKLGAQLVAIFNTHHHYDHVGANNQLQQYFPNLCIYGGSEDRGRIPGQQVFLKEGDRVEFGQRVGEVLFVPGHTRAHIAYYFPPKLSQETGELFCGDTLFGGGCGRLFEGTPTQMVNSLTKLRNLPDNTRVWCAHEYTLKNLQFALTVDPDNLVLKNRYHQVKEFRHQGQATVPSILGEEKLTNPFLRWDNSAIQLTIGMTDPARVFGKLRGMKDTF
>NC_011726.1|WP_012595724.1|2530333_2531143_+|ion-transporter
MVDQPITLKKKLSHYLDDFDSLTGIIINLIILGLILLSFLIFVVETYPISESLLIRLKQLDKIILLVFTLEYIIRFWCSDNKLRFLFSFFSWIDLLAIVPLFVGFLDIRYILIIRWFRILRLIRLIELATFLLKIKTEDGVILTRIFLSLLSLVFIYSGAIYQIEHQTNPQIFENFFDALYFSIVTMTTVGFGDVTPLSETGKFITLMMIISGIILIPWQISILTQQLLKITNKSTKLCFHCGLTVHEHDANFCKICGAKLEKKQEIIS
>NC_011726.1|WP_012595725.1|2531217_2531985_+|Uma2-family-endonuclease
METVFPYLEIPAENLIYDDGEPLESNRHRIAMNVLISSIYQSFADRQDFFAGGNMFVYYSATQRMNRDFRGPDFFVTLNVDGNQSRKAWVVWNENGRYPDVIVELMSPSTAVIDKTIKKDLYEQIFKTKEYYIFDPFESNSLQGWRLDDHQHYQEIIRDQRGWLSSETLELYLGTWYGTIHHESASWLRFYNQEGHLILLPEEAAQQQAEIAQQQAEMAKQQAKMAEERAETAEQKAQRLANRLRELGINPDEIE
>NC_011726.1|WP_012595726.1|2532036_2533068_+|cobalamin-biosynthesis-protein-CobW
MHKIPVTVITGFLGAGKTTLVRHLLQNNQKRRIAVLVNEFGEVGIDGELLRDCQICDEDETPNNNIIELTNGCLCCTVQEEFFPTMQQLLERRENLDCMLIETSGLALPKPLLQAFRWPEIRNGATVDGVVTVVDTQALAAGTLVGDLTALEAQRKADPNLEHETPIEELFEDQLACADLVLLTKTELIEPSQLTKIQDWLKQELRPGVKVIPCHNGVINPDILLGFNAAVEDNLESRPSHHDEEEEHDHDDDINSVQVILDQQFEPQALIEKLKTLVETTEIYRIKGFVNVANKPMRLVLQGVGDRFDTYYDRLWKPDELRQTRLVFIGRQLMLDNIKAKLD
>NC_011726.1|WP_012595727.1|2533588_2534140_-|DNA-starvation/stationary-phase-protection-protein
MATVQGLVRAFGEVGDNAVLLDKSVTVPVCEGLNMVIASFQGLYLQYEKHHFVVEGSEFYSLHEFFNESYDEVRGHVHDLAERLNGLGGIPVASFSKLAELCCFEPEMDGAYDCRTMVEHDLAGEQAIIKLLRKQAAQAESLGDRATRYLYEQILLKTEERAYHLDHFLVSDSLTLAFVGNGN
>NC_011726.1|WP_012595728.1|2534491_2534743_+|hypothetical-protein
MNSANLPLKSSQIVQVPWNDRWTVYHRLQELGISCYCSSNQPLEVQLSSPTAVIQLWSVVKHCSSSRQELIQWLQTCWDLKKT

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Crispr_ID: NC_011726_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_8

3093017-3093354

TypeV-U5

V-U5

Consensus_repeat	Method
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	PILER-CR
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	CRISPRCasFinder
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	CRT

4 spacers

c2c5_V-U5

The CRISPR arrays of NC_011726_8

>merge|NC_011726|8|3093017-3093354|PILER-CR,CRISPRCasFinder,CRT
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAGTTATGTTGCGTAAAGGAAGGGTGAGTAGTCGGAATTTCTCGGAGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAGTTCACAGCAAGATCTAGCCGTACGACTAAACTGCCAGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAGAAACCAATAGGAGCTAGATAAAGCTTTTTTATAGTTAGCGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAGAATAAGGATTAATTTCCCAAGTTAAGTTTTTGAAGTTTCATCAACCCTCCTGACTTGGGATGGGTTGGATT

>NC_011726|8|5|3093017-3093283|PILER-CR
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	TTATGTTGCGTAAAGGAAGGGTGAGTAGTCGGAATTTCTCGG
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	TTCACAGCAAGATCTAGCCGTACGACTAAACTGCC
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	AAACCAATAGGAGCTAGATAAAGCTTTTTTATAGTTAG
CGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG

>NC_011726|8|7|3093017-3093354|CRISPRCasFinder
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	TTATGTTGCGTAAAGGAAGGGTGAGTAGTCGGAATTTCTCGG
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	TTCACAGCAAGATCTAGCCGTACGACTAAACTGCC
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	AAACCAATAGGAGCTAGATAAAGCTTTTTTATAGTTAG
CGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	AATAAGGATTAATTTCCCAAGTTAAGTTTTTGA
AGTTTCATCAACCCTCCTGACTTGGGATGGGTTGGATT

>NC_011726|8|3|3093017-3093354|CRT
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	TTATGTTGCGTAAAGGAAGGGTGAGTAGTCGGAATTTCTCGG
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	TTCACAGCAAGATCTAGCCGTACGACTAAACTGCC
AGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	AAACCAATAGGAGCTAGATAAAGCTTTTTTATAGTTAG
CGTTTCATCAACCCTCCTGATGTGGGATGGGTTGAAAG	AATAAGGATTAATTTCCCAAGTTAAGTTTTTGA
AGTTTCATCAACCCTCCTGACTTGGGATGGGTTGGATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_012596250.1\|3107938_3109273_+\|TRAP-transporter-large-permease-subunit	unknown	unknown	gnl\|CDD\|227010
NC_011726.1\|WP_012596244.1\|3096594_3097095_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377670
NC_011726.1\|WP_012596249.1\|3107233_3107827_+\|TRAP-transporter-small-permease-subunit	unknown	unknown	gnl\|CDD\|227011
NC_011726.1\|WP_012596251.1\|3109442_3109742_+\|DUF5132-domain-containing-protein	unknown	unknown	gnl\|CDD\|319213
NC_011726.1\|WP_012596245.1\|3097066_3101347_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379049
NC_011726.1\|WP_012596238.1\|3084484_3085645_-\|restriction-modification-system-DNA-specificity-domain-containing-protein	unknown	unknown	gnl\|CDD\|341150
NC_011726.1\|WP_012596246.1\|3101441_3103424_+\|hypothetical-protein	c2c5_V-U5	-	gnl\|CDD\|273793
NC_011726.1\|WP_012596235.1\|3077964_3078468_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377670
NC_011726.1\|WP_012596241.1\|3090391_3092440_+\|hypothetical-protein	c2c5_V-U5	-	unknown
NC_011726.1\|WP_012596248.1\|3106018_3107158_-\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270400
NC_011726.1\|WP_041229656.1\|3079714_3080179_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275228
NC_011726.1\|WP_012596240.1\|3090065_3090242_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369567
NC_011726.1\|WP_012596243.1\|3095697_3096588_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379165
NC_011726.1\|WP_041229657.1\|3081522_3082386_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275228
NC_011726.1\|WP_012596236.1\|3078475_3079711_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_012593072.1\|3080458_3081451_-\|transposase	unknown	unknown	gnl\|CDD\|372577
NC_011726.1\|WP_012596237.1\|3082403_3084482_-\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|280533
NC_011726.1\|WP_012596239.1\|3087314_3089942_-\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|226581
NC_011726.1\|WP_157861331.1\|3093696_3095691_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|378147
NC_011726.1\|WP_012596247.1\|3104860_3105925_+\|uroporphyrinogen-decarboxylase	unknown	unknown	gnl\|CDD\|215237

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_012596244.1\|3096594_3097095_+\|hypothetical-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.04212e-10
NC_011726.1\|WP_012596249.1\|3107233_3107827_+\|TRAP-transporter-small-permease-subunit	gnl\|CDD\|227011	COG4665, FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component [Secondary metabolites biosynthesis, transport, and catabolism].	1.30189e-51
NC_011726.1\|WP_012596251.1\|3109442_3109742_+\|DUF5132-domain-containing-protein	gnl\|CDD\|319213	pfam17195, DUF5132, Protein of unknown function (DUF5132). Proteins in this family are uncharacterized, but have been identified as members of a gene cluster for the synthesis of Ansamitocin.	6.30224e-08
NC_011726.1\|WP_012596245.1\|3097066_3101347_-\|hypothetical-protein	gnl\|CDD\|379049	pfam13173, AAA_14, AAA domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.000259484
NC_011726.1\|WP_012596238.1\|3084484_3085645_-\|restriction-modification-system-DNA-specificity-domain-containing-protein	gnl\|CDD\|341150	cd17261, RMtype1_S_EcoKI-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit TRD-CR, similar to Escherichia coli str. K-12 substr. MG1655 S subunit (S.EcoKI) TRD2-CR2, Escherichia coli A58 S subunit (S.EcoEI) TRD2-CR2, and Aminomonas paucivorans S subunit (S.Apa12260I) TRD2-CR2. Escherichia coli str. K-12 substr. MG1655 S subunit (S.EcoKI) recognizes 5'... AACNNNNNNGTGC ... 3', Escherichia coli A58 S subunit (S.EcoEI) recognizes 5'... GAGNNNNNNNATGC ... 3', and Aminomonas paucivorans S subunit (S.Apa12260I) recognizes 5'... GCCNNNNNCTCC ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.EcoKI-TRD1 recognizes AAC/GTT and S.EcoKI-TRD2 recognizes GCAC/GTGC, S.EcoEI TRD1 recognizes GAG/CTC and S.EcoEI TRD2 recognizes GCAT/ATGC, and S.Apa12260I TRD1 recognizes GCC/GGC and S.Apa12260I TRD2 recognizes GGAG/CTCC. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	2.11825e-76
NC_011726.1\|WP_012596246.1\|3101441_3103424_+\|hypothetical-protein	gnl\|CDD\|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	0.00119402
NC_011726.1\|WP_012596235.1\|3077964_3078468_+\|hypothetical-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	2.93812e-05
NC_011726.1\|WP_012596248.1\|3106018_3107158_-\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270400	cd13682, PBP2_TRAP_alpha-ketoacid, Substrate-binding component of an alpha-keto acid binding Tripartite ATP-independent Periplasmic transporter and related proteins; contains the type 2 periplasmic-binding protein fold. This subgroup includes TRAP transporters that bind to ketoacids such as pyruvate and alpha-ketobutyrate, xylulose, and other unknown ligands. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0
NC_011726.1\|WP_041229656.1\|3079714_3080179_-\|hypothetical-protein	gnl\|CDD\|275228	TIGR04435, ABC_transporter, restriction system-associated AAA family ATPase. Members of this family are AAA family ATPases by homology. They occur regularly in a conserved gene neighborhood with the restriction (R), modification (M), and specificity (S) proteins of an apparent type I restriction enzyme system, plus one additional uncharacterized protein. It is not clear whether members of this family contribute to restriction per se, or to another process such as transfer of mobile elements.	1.48271e-12
NC_011726.1\|WP_012596240.1\|3090065_3090242_-\|hypothetical-protein	gnl\|CDD\|369567	pfam07878, RHH_5, CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5. This family contains bacterial proteins that form a ribbon-helix-helix fold. This fold occurs in many examples of bacterial antitoxins.	2.71944e-16
NC_011726.1\|WP_012596243.1\|3095697_3096588_+\|ATP-binding-protein	gnl\|CDD\|379165	pfam13401, AAA_22, AAA domain.	3.28745e-23
NC_011726.1\|WP_041229657.1\|3081522_3082386_-\|hypothetical-protein	gnl\|CDD\|275228	TIGR04435, ABC_transporter, restriction system-associated AAA family ATPase. Members of this family are AAA family ATPases by homology. They occur regularly in a conserved gene neighborhood with the restriction (R), modification (M), and specificity (S) proteins of an apparent type I restriction enzyme system, plus one additional uncharacterized protein. It is not clear whether members of this family contribute to restriction per se, or to another process such as transfer of mobile elements.	9.28809e-07
NC_011726.1\|WP_012596250.1\|3107938_3109273_+\|TRAP-transporter-large-permease-subunit	gnl\|CDD\|227010	COG4664, FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component [Secondary metabolites biosynthesis, transport, and catabolism].	3.58333e-167
NC_011726.1\|WP_012593072.1\|3080458_3081451_-\|transposase	gnl\|CDD\|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.30183e-34
NC_011726.1\|WP_012596237.1\|3082403_3084482_-\|N-6-DNA-methylase	gnl\|CDD\|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	1.19016e-20
NC_011726.1\|WP_012596239.1\|3087314_3089942_-\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|226581	COG4096, HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	5.92702e-135
NC_011726.1\|WP_157861331.1\|3093696_3095691_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|378147	pfam09299, Mu-transpos_C, Mu transposase, C-terminal. Members of this family are found in various prokaryotic integrases and transposases. They adopt a beta-barrel structure with Greek-key topology.	5.66063e-09
NC_011726.1\|WP_012596247.1\|3104860_3105925_+\|uroporphyrinogen-decarboxylase	gnl\|CDD\|215237	PLN02433, PLN02433, uroporphyrinogen decarboxylase.	0

>NC_011726.1|WP_012596241.1|3090391_3092440_+|hypothetical-protein
MTLKTLECRLYAPSDTLRYLWLLMAEKNTPLINEIINHLSEHPDFDQWFKAKQIPKSAISDICNDLKSQENYQNQPGRFYSSAISLTHYMFKSWFAVHKQLQRRIEGKRRWLNLLKSDQELEQNCGQSLEIIIQKAEEILKLMDSEKSQSSSKPKKPKKPKKKKKSSSEETITLFDRLFKAYNQGNDSLESYALAYLLKNNGQIPEDDEDLDKFALRKRKKEIEIERLQQQLENRIPLGRDLTGELWQEMLTIVNESIPQDENEASAWQAKLLKKSHNIPYPVAYETNTDLKWSKDSRGHLLVTFNGLVESLKKLNLNPEFEIRCDRRHLPWFQRFCKDQEIKANNDQHSSALFVLRSARLIWREGQGKEDPWKIHQLYLQCSVETQLWTEAGTKQVQSEKMVEFQLNQLRMKPELTFPIFFRSQSLPTYFNLWKVITSYRILKFLEKGDFTKAQKNFQDAIKRTESCLENLQSSYLTSQKSLYQGNPEIIMGVAMGLSQPATIAVVNVVTQEVLTYRSLKQLLGKNYNLLNRQRQQKQKLSHQRHKAQKKDAFNQYGESELGQYVDRLIAKAIVQVAKEYQADSIAVPKIRQMREIIQSEVQARAERKIQGYKEGQKKYAQQYRENVHQWSYGRLIESIHQASAKFGIRVEIASQSYQGSFQEQAQNLAIAAYTNRLEAVG
>NC_011726.1|WP_012596240.1|3090065_3090242_-|hypothetical-protein
MSKRVYLTLPDKVYEALERWADEQGRPVANLAAYLVERAVEKAESEGKIPLNKNNPKT
>NC_011726.1|WP_012596239.1|3087314_3089942_-|DEAD/DEAH-box-helicase-family-protein
MTSYNEADTRAKLIDPQLKLSGWGENQIEREHYFAKRQQITAGRIYLVGDQSRRRQPCRVDYLLRYQGQAIAVLEAKDESHSVDAGLEQAKAYARKLDLPFAFASNGHSFIEFDFFSSCSQELSTFPTPQQLWQRWETYRQGKVKSGRVAENGGNYGVLSVNPLLYPVCPESQCGKVPRYFQEVAIRRVIERILKQQRRILLTMATGTGKTFTAFQIVWKLKQSGWLRKPILFLSDRLILRDQSYNTFAPFVAPSADPRGVIEKGKFNSNRELYFALYQALDALKEGESLFSQIPADFFGLIIIDECHRSGFGKWNGILQHFTGAIQLGMTATPKQDESIDTYAYFCAEESEIPLDPDDNSKGTWKPPAYQYSLGQGIDDGFLATYKVHKVRTTVDKNGLHLQEARIQGAEIYIPEDVEPRQQYLTGQFEREITLPDRTKTMVSHLAGLLRQFGEREKTMVFCVDMTHARLVARLLQNEFAELGYSNYAVPIVSEEGEAQAWLEQFQDSDRLTPIVATTAELLSTGVNVPSCRNIVFMKPISSPILFKQIIGRGSRIDPATGKEWFRIIDYVGASRLFDQWDRPIGELPQAITGARTSIIEGRVIHGDTEEFLVGASVSALIGVNQQLSPILTDDNGYFRLEALPAGKIRLFLRGNGFRSREITLETAENETLTVVLALNSVKPPVGKIRVEGLEVTIADEVTFIVDATGEQLTLAQYLDYTKAKIRGYVPNWSQLHQIWIDSEQRKLLLRELTTASVYIEVLGEVLAQPKADQFDLLAHIAFNKPIHTRDERVEAFLNYEQWYLEAQTEEAREVILGLLDKYRLAGIEEIVNPEVFRLSPFQEMGQIKGVILRLGTMENLRQIFREIQQKLYRQ
>NC_011726.1|WP_012596238.1|3084484_3085645_-|restriction-modification-system-DNA-specificity-domain-containing-protein
MSDESQKFIKLGNLIKFKYGKSLPNRERDPDGKYLVFGSGGKIGLHNSYLTESPVIVVGRKGSIGSTFYSDNPCWCIDTTYYVDQFSSNLYSKYLYYFLNTLKLDRLNRAATIPGLSRDDLYTFSIPIPYPNNPKLSLDIQQRIVARIESLFGEIKRNRLLLEQMRLDNDLLLPNALDEVVERLDSKRQTLLDVIQEKPRNGWSPKCDNDPNGVPVLKLGAVLRFQYNPDEIKRTSLPTDENAHYWLEAGDILISRSNTLDLVGHASIYSGIPYPCIYPDLIMRFRVNPNKADSKFLMYWLQSKEVRHYIQTNASGASPTMKKIKQETVCNIPFPIISLEEQSYFAYHLDAIQQEVNKINRIIEEDEQNFKYLEQAILEKAFRGEL
>NC_011726.1|WP_012596237.1|3082403_3084482_-|N-6-DNA-methylase
MTIAENLNKIWSEFRQFGITDDLVVIEYLARLLLEKVLDISQSNIGIHFDGMWPTYYQVMGFLTDLPLYQLYSSAELQSIIDTVTNLVPISTLPRHPKDIRNLNLELIQENLKNAINEVENIPNLFNHYILFRLSTRQSGGRYPTPRHITQFIFNLAQIEPHHSLADFACGSGGFLVERELTIDNYSKTWGIDISPEWIRLAYTNIALKKFPPQLGSGNAINVANSDDWKDRVCDRILMNPPFGEKIDSKLATENLGKNVGSRSETALTTLAIQKLAEDGIAGILVPSGLLFSNSKAERELRQTLIDDYHLKAVITLPKDALQPYSSLQSHLLLIHRFPSPNLGEGLGVRETWFFQLEEDGYSSGRSRDLTQKPDLSKSDFPFVEKVFKRQGDEFDYFFPDSHPEIGIKVIKNDENELLGFVFEGRETEINFVTFYPSPSPSTSPFLLIDTLPIDNPKLSIKIPLDGSEVNIIENPSQYLNDLFKPTKNNPIPETRLYSQPVKGIAIAFNSDTIITKENLRILGILIPSNQVINRNYDLRPEEYIDKPLETRLNNSPVELLTRIYSNQRQLTQNLETLFSRIELPSISTEKLPSPIVDTFTPIGKFNPQQQTIWDKIQRQTESYTDDNGDNYEIALHFTPQDIESEDNDEISDITQRTLELLEAMGVIIPVTLHNKLYYRRVTQRDLWTNSD
>NC_011726.1|WP_041229657.1|3081522_3082386_-|hypothetical-protein
MKLKRFFIEYRVLQDLEIFFGPSLKESKAFTDSPAYNLDFLVGVNGTGKSTVLRILFELFRLLERQSAIPFPFELEYEIEKNGQAKTIKISNRYQDLDKETIEYKQTPDVGEIDNNGKYKPSELSADILPDLVIAYTTGSETNWSIVEDNYLDYITSPLPSLSQIELAIQELPGKPQITIEEDDTSTSESKCLFIPSNDISLITLCGLLTDLAKPNRRLSKILEASKISKLSGFSLKFRKLNSKPQDWEKVEELAKLTSKCLRIGTDYQLIFDLSDLNLPKRLIEIY
>NC_011726.1|WP_012593072.1|3080458_3081451_-|transposase
MESYTWGHIHKYPKQTKRLLGIDYQQLEQLIALGKLLHQENKEKIEKTKIRINQPGSGTYSKLSEEEQIVLMLVYLRHNISFQILGLLFQVSESTAHNIFSYWQKLFEGELPSSLLEQVKKFQEEEEIIQEQLTDYELIVDSSEQPIERPSDCQEQKKYYSGKQQRHTLKNQFIVLPKAQDIIDVVMGKPGPMSDIKICRQTLSKFDVQQTFSGDKAYIGETQIKTPYKKPKKGELTESQKKENKALSSNRIFVEHLIRVVKVFKVVQERFRLQKSRYKSVLLTVCGLVRLRIGSLILRIIESEKSGEVIDVKMSHSFISKLDFVSLNPD
>NC_011726.1|WP_041229656.1|3079714_3080179_-|hypothetical-protein
MCLLTLLETDEALILLDEPEVHFNDFWKRQIVNLIDINLKNRQSHILISTHSSITLTDVPKENIMVLDRNGNYTNKSLKPSMNTFAADPSDIMVHVFGSPYPSGELSINRLENELENKFNRSPQERKETLENLKDVVASGYWRFVIRQELQTLK
>NC_011726.1|WP_012596236.1|3078475_3079711_-|hypothetical-protein
MLYRIELPEITLERLTDVVYLQMTLLRYASYRSPSQLNKEDCAVYFEKSQRFRGRHKEIAEWIFRGSTKRKLLETFASGNQSEKLAWSRNLHQDVVKLLYHPCGLLNPYIKDQNPTEWKQAGVTFLINFYEEYLDSLPKNFFSESQINNITKGSIRESFEQINKTLEVCPTCDFEIIRDEIDHYLPKSVYPHLSCHPFNLMPICGACNDKQIKGNIDLLRKGIKIPRQLEQILLPYRTDGLAKHIYLDFDLSENFRQPINIQYYSQTTSSYDSNYLKIHANTYKLSSRWIKMSSNMESSLFRTIKKIIKNPDNKPYLNIFDIQEILDQYLSEELIDEQGKTGFAFPMTWWLATLINQQIEPVINSEEEIDIQDYPFLAEIATWIEQETIQHPQFMNNETLKKARELRKKAQ
>NC_011726.1|WP_012596235.1|3077964_3078468_+|hypothetical-protein
MDKEYWLTKVEPYEGESISHFLGRFRRTKGNRFSAASGLGQVAGLGAILARWEKLYFNPFPNEQELEALGKVVMLDVEDLRKMLPQKGMVTQPKPIMLCAVCYGEKPYHRMVWQDKHQRGCEVHGLELLSRCINCKRLFPIPSKWEEGKCLLCGLAFAKIAKHQKPI
>NC_011726.1|WP_157861331.1|3093696_3095691_+|DDE-type-integrase/transposase/recombinase
MSKSNITSHKTEINREEQDLEQTESQKSHQNHLKLINTQLSPATEEIINALEPILQASNTKQRTQAIEKASQMLGKSTRTIRRMLAKMTHEGVATLIRGRQDKGQYRISKQWRDFIIKLYKWGQQDGSRQNISQIYNALIALEAQGEKLRTQMNKKDGYAKLLKPYPEVLEDLIAGKYPSHPTVYKVVRDELERKNKSKARHPGADIDHQVVQTIEENLYITHSNQIWQADHTKLDVFVFESISKENPSAKQEVIRDSKGEPIRPFLTVIIDSYSGCLMGYYLGFVAADSHRVALALRNAILPKQVKEKYGLQNEWEQSGIPEYLVTDRAKEFKSHHAKLIAMQLGFQWKLRAFPSAGGLVETIFNQTNNEVLKSLPGYTGKNVQERDNNVEDHVCMTFEELERELVQYFVDHYNQHHYPKAKIDPQFEVHRRANRWKYGLISEAEIIDERSLDICLLKQAHRKVQKYGTIQFETMIYMGNCLKDYIGEEISLRYDPRNIVTLLAYTAPKNGEPSEFIGVIKARHFEYEQMTFDELKWIIHKLRSQSKDPENISILNERYNHLNFIAKKRTEKGRRSKKAQDKRDQVTNQSTLTEIFPENAPQPNNNSEIVSEEATKTVKMGRKSKKRIITQPLPPETNARVRRRSSGIMTNIQDWNEYKKNNW
>NC_011726.1|WP_012596243.1|3095697_3096588_+|ATP-binding-protein
MAKGNLEQLKVSAKTQSEEVNGRSAAQKAEIERIGQADTYCPLSRDEELFTWLNDQRDLRLCGYIMATRGSGLPKACEYYRMAHVKRRGSLFEMPATVFYVEMLQKGKATDLYRAILGEFGHPLSNLGTLRHLRSRTWDNLKRYGVKILIIGKADYLKLEAFNELIDLYDHSRISVILAGTHYLEDILGRNHPAYVNLCNSFLEWYEFPGLSSKDVGIVVEHWEKTFLSPKYRLNLTQYPEIVETLTEKSGGLIESLYDILRQIAMFKVDDPDFELTPSNVLAYLSHRKPPTLKLG
>NC_011726.1|WP_012596244.1|3096594_3097095_+|hypothetical-protein
MGKSEAKFQPPWYVEPYEGESISHYLGRYCRHESVSLSALGKATGLGAILGRWEKFRFIPFPSEEELEAFGELIGLSVAQLKGMLPQESMKLLPIRLCGLCYSQKPYHRMEWQYQSRLNCTVHGVKLLTKCPSCGERFAIPSRWVEGKCLRCGMGFKSMRKEQKHD
>NC_011726.1|WP_012596245.1|3097066_3101347_-|hypothetical-protein
MSSFSHSDATPTYRGYRLQLLYTLWRILSENKKNNFTFQPEGQEDLAIYDEAGHLIEIIQVKARSENISLSSFSPKKVDSFFNRSHILINSTSSLKTIRVISFGCFGQDFEEACNGNINKLKAESEKLSNYGHLSSEEAEKLLKKINLETVTEENLEKEALGLLKQGLAGIDYKCAFDIITYWLYICAENQIKITYQSITEKLNKIGEFLVERTTYHKEWFTSILPIENNFIDEQKKEYLSHEFYRGISARYEHILANVDVIRKNELEKISQEFNRNKVVIIHGASGQGKTTLAYRYLHEFHPEQWRFKIQLIENRQHSLSIARAIEGYAKAIGIPIIMYLDVSHNDNGWTDLVKQLASYQNIYVLVTVREEDYRRASVSGTEFPFSDIELTFDANEAKEIYQSLVEKKATVEFLNFEEAWDRFYQEHCFHEKLLMEFVFLITKGQFLKQRLLQQVRRLEDEVRIGKFSNKELEFLKLVSIASAFEARLDVKSLVKFLNLPVPRRTIELLEKEYLLKCSDDGSLIYGMHPIRSQILSDILTDPSLSAWSESAIECFPFIIESDMESFLLYSFSRKYNEIRPLVNSLMFYQPKYWSGIAGINKALIWLGIKDYVEENKALIQTLHSDLGSGFWILLSYDITDAMTDSESSIWQCLRTIVPESYVNEIENLQSQQTDKSKVFQYSKKWLSNIIFIIEQPFGYLDWQAMSEVFFWLGRLQIDFCLDNLINKIDFNNLFQDLPIDVLADLILGLSFGYEEKFNIWMNTHRMQIVQRFRQETQTIILEDDNQKLTAHFLIPTYARKNENSFNNSIKREDESELHQEAMWRIDLLRKLLPDRQLYACCGYGHRMFTEELPYDETVKTGIAKENLPVTWLTSINSTFTGIADQFFKPQNWSEYSTQVIRLRTNILNMLGKLDKGLINYFRQSQAFNWFDKYINPPEWRDCKQQLVYTPLLPACSANEWGFNNKNDLFLSNKNNALAFQDYSSYLKVFREYHQNLYNFFNQAEQGMVITSALGRKEDKERVLEIAKSNNLDPKLSHIAAHNLANTLKGLKRFQQEFRRKFSSYLDLEKLKTLESKELETFNNLCCLWLFFAFYPGKHFQDPIKECHKEITDKLKKIRNKLKKEFCKISNNNLSVQILSENVLWEHDKTLWITIDGSNPIEVYIHIVVVIKLLTQAINVLGNTPLRRYILDLNWTYVAIIPLVKGKSLQGTASHIYIHTLVYRDEEELNWWNYAQKEIPKDAISHLSIERHAEYLLKNPNHFLTSFTSLKFLLAHIKDLNRMPKNQIDNFAFKQLKNYFDELEESWLKILDFSYNSLERLENLKEETSLDNLQKYDLSKDNLEEFINILKEIFFSLQNLTKTTAETILLGDTQNIDNIFSTICTWSHTLEQVENYIFLIYFIWIAEILDNSNNIIEFNHASVLSS
>NC_011726.1|WP_012596246.1|3101441_3103424_+|hypothetical-protein
MTHITVVQCRLIAPESTLQHIWKMMAQQQTPLINQLLHDINTHPDINTWLTANQLPSKLVETLAQPLKTQSPYQGLPGRFITSAIILVKEMYASWFAIQTQKRLSLEGKKRFLTILKSDKQLIQDSQTDFLTLCYKAQQLLKRTQNKLKLDEPQHSEKAHWSIINALYPAYNNAKTPISRAAFALLIKNNGQVPDTPENPDYYQQRRKRKEIQIRRLEEQLKASLPKGRILDSKHWENTLKLAQTPITTIEEITSLQTQLLQKYSHLPFPVFYGTNTDLTWFKNPQGRICVKFNGLNQYPFQIACNKRQYPWFQRFFTDYQSYKSHKQQVPTGLMVLRSARLLWQPTNGQGEPWNTHHLSLHCAIDNDLWTISGIQQVKQQKILQTEQKIANFHSKALEKELTPNQQQRLKASQTSLNLLKTFDINEFFPSKCSLYQGSPDIILGVSIGLENPATIAIINISTQEILTYRTTKQLLSRTRKVRNKKPNSNNSNQSLSSAYKQISNYELFLQYQQQKHHNQHQRHNAQINDANNNYGEANLGLYLNRLLAKAILELAQQYQVSLIILPSLKNKRELIESEIRAKAELKYPGCKEKQDSYAKDYRTNVHQWSYQQLIKCIESKAAQIGIDTATGKQMNLETSQDQARNLVLNFCQKFSPTQV
>NC_011726.1|WP_012596247.1|3104860_3105925_+|uroporphyrinogen-decarboxylase
MTQGNNTPYLLRAARGEILDRPPVWMMRQAGRYMKVYRDLRDKYPSFRDRSENADLAIEISLQPWKAFRPDGVIMFSDILTPLPGIGISFEIPESKGPMIDSPIRTQEQVDNLHSLDPEASLPFIKTILKALRDEVKNEATVLGFVGSPWTLAAYAIEGKSSKDYANIKRMAFSEPAILHQFLSKLADAIAVYVRYQIDCGAQVVQLFDSWAGQLSPQDYKVFALPYQQQVVRQVKATHPDTPLILYISGSAGVLELMGQSGVDIVSVDWTVDMADARQRLGRNMMVQGNIDPGILFGSKQVIRDRILDTVQKAGKGGHILNLGHGVLVGTPEENVGYFFETAKQVDQLLAVPV
>NC_011726.1|WP_012596248.1|3106018_3107158_-|TRAP-transporter-substrate-binding-protein
MKRRNLVKATSQGAIAATVAGIAIGCSKSQNQATSNNTELPKITWQMATSWPLSLDTIFGGATVFAERVAQMSGGRFKISPKPAGDLAPPLEVLNVVKQGAVPCGHTAAYYYIGQNPAAAFGTAVPFGLTAQQQNTWLYEGEGLKLLQELYASQFGVIQFPAGSTGTQMGGWFRKEVSTINDLKGLKMRIPGLGGQVMSKLGVLVQNLPGGEIFQALQTGAIDAAEWVGPYDDEKLGLNKVAQYYYYPGWWEPGPTLEVQINLNAWKKLPVEYQQMIQTAAFEANQIMLARYEARNYEALQRLLQSGTQLRPYSDEILNAAKTSAFELYDEFAAKNADFKAIFENWQKFRDGVFTWSNLNQGSFERFVYKTLDTPSQGS
>NC_011726.1|WP_012596249.1|3107233_3107827_+|TRAP-transporter-small-permease-subunit
MPTLFKFAQTIDYLTEQVGRLLYSIVILTVGIGFYNVAARYLGRFVGLKLSSNALIELQWYLFSLMFFIGFPYILKHSANVRVDFLYAHWSPKRQALIDFLGTVLFLIPFCLIGIYVTFNPVLQSWGQLPDGSWGAWEVSSDADGLPRAPIKSMILVSFALLLLQAISQAIKYGAILQGYEPALREIQSETEKPPIE
>NC_011726.1|WP_012596250.1|3107938_3109273_+|TRAP-transporter-large-permease-subunit
MGFEWLAIAMFVGFFFILISGYPVAPAFAGTAIIFGLMGLAVGAFDINLLLLLPNVWFQTMSNFTLLAIPFFVFLGVVLEKSGLAEELLETIGIVLGPLRGGMALAVIIVGTLLAATTGVVAATVIMMGLLSLPVMLRYGYDKRLAAGVIVASGTLAQLIPPSLVLVVLSDQLGVSVGDLFLGALIPGLMLSASYAIYVLVLAFLYPNVAPALPLEARRVQGKALIKQVIKAVLPPCLLILAVLGSIFFGIATPTEAGAVGAVGACFLAASKGRWTQNLIKDAAHDTAVVTSVVLMILFCSSFFSIVFNGLGGKELITQFLLNIPGGYISFMIVSNLVIFILGVFLEFIEICFIALPLLVPAAQALGIDMVWFGVVIAINLQTAFISPPVGFSLFYLQSVAPKEIPTTDIHKSALPFMLLQGLILIVVIIFPQTVRWLIDISYN
>NC_011726.1|WP_012596251.1|3109442_3109742_+|DUF5132-domain-containing-protein
MALKDFVPHLDLKDIAEDLGIPGITAIVLLPVLIPAAGKAAKPLAKATIKGGIILYEKGKGVIANVGETLEDLIAESLAELAEETSEKAAIAEADVMAN

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Crispr_ID: NC_011726_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_9

3103986-3104241

TypeV

Consensus_repeat	Method
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGA	PILER-CR
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAG	CRISPRCasFinder
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGA	CRT

3 spacers

c2c5_V-U5

The CRISPR arrays of NC_011726_9

>merge|NC_011726|9|3103986-3104241|PILER-CR,CRISPRCasFinder,CRT
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGAATGATCAGGCTCCGATAGACTGGGGTGGCTTTGGTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGAACTTAATCGCCATCAAAATTGCCTCTATTTCTGCGTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGAGCTAAAGTTTTCGCTTGATGCAGTGGGGGTAGCAAAGGTTTCATACAGGTTTTTGACCTCCTATTGATTGAAAGG

>NC_011726|9|6|3103986-3104241|PILER-CR
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGA	ATGATCAGGCTCCGATAGACTGGGGTGGCTTTG
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGA	ACTTAATCGCCATCAAAATTGCCTCTATTTCTGC
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGA	GCTAAAGTTTTCGCTTGATGCAGTGGGGGTAGCAAAG
GTTTCATACAGGTTTTTGACCTCCTATTGATTGAAAGG

>NC_011726|9|8|3103986-3104240|CRISPRCasFinder
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAG	AATGATCAGGCTCCGATAGACTGGGGTGGCTTTG
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAG	AACTTAATCGCCATCAAAATTGCCTCTATTTCTGC
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAG	AGCTAAAGTTTTCGCTTGATGCAGTGGGGGTAGCAAAG
GTTTCATACAGGTTTTTGACCTCCTATTGATTGAAAG

>NC_011726|9|4|3103986-3104241|CRT
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGA	ATGATCAGGCTCCGATAGACTGGGGTGGCTTTG
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGA	ACTTAATCGCCATCAAAATTGCCTCTATTTCTGC
GTTTCATACAGGTTTTTGACCTCCCATTGATTGAAAGA	GCTAAAGTTTTCGCTTGATGCAGTGGGGGTAGCAAAG
GTTTCATACAGGTTTTTGACCTCCTATTGATTGAAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_012596244.1\|3096594_3097095_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377670
NC_011726.1\|WP_012596249.1\|3107233_3107827_+\|TRAP-transporter-small-permease-subunit	unknown	unknown	gnl\|CDD\|227011
NC_011726.1\|WP_012596251.1\|3109442_3109742_+\|DUF5132-domain-containing-protein	unknown	unknown	gnl\|CDD\|319213
NC_011726.1\|WP_012596250.1\|3107938_3109273_+\|TRAP-transporter-large-permease-subunit	unknown	unknown	gnl\|CDD\|227010
NC_011726.1\|WP_012596240.1\|3090065_3090242_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369567
NC_011726.1\|WP_012596246.1\|3101441_3103424_+\|hypothetical-protein	c2c5_V-U5	-	gnl\|CDD\|273793
NC_011726.1\|WP_012596256.1\|3116037_3116967_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|234835
NC_011726.1\|WP_012596253.1\|3113119_3114352_+\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|237106
NC_011726.1\|WP_012596241.1\|3090391_3092440_+\|hypothetical-protein	c2c5_V-U5	-	unknown
NC_011726.1\|WP_012596254.1\|3114582_3115677_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173845
NC_011726.1\|WP_012596238.1\|3084484_3085645_-\|restriction-modification-system-DNA-specificity-domain-containing-protein	unknown	unknown	gnl\|CDD\|341150
NC_011726.1\|WP_012596245.1\|3097066_3101347_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379049
NC_011726.1\|WP_012596243.1\|3095697_3096588_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379165
NC_011726.1\|WP_012596248.1\|3106018_3107158_-\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270400
NC_011726.1\|WP_012596255.1\|3115685_3116018_-\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|212139
NC_011726.1\|WP_012596237.1\|3082403_3084482_-\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|280533
NC_011726.1\|WP_012596239.1\|3087314_3089942_-\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|226581
NC_011726.1\|WP_157861331.1\|3093696_3095691_+\|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl\|CDD\|378147
NC_011726.1\|WP_012596247.1\|3104860_3105925_+\|uroporphyrinogen-decarboxylase	unknown	unknown	gnl\|CDD\|215237
NC_011726.1\|WP_012596252.1\|3109993_3112984_+\|cation-transporting-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_012596244.1\|3096594_3097095_+\|hypothetical-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.04212e-10
NC_011726.1\|WP_012596249.1\|3107233_3107827_+\|TRAP-transporter-small-permease-subunit	gnl\|CDD\|227011	COG4665, FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component [Secondary metabolites biosynthesis, transport, and catabolism].	1.30189e-51
NC_011726.1\|WP_012596251.1\|3109442_3109742_+\|DUF5132-domain-containing-protein	gnl\|CDD\|319213	pfam17195, DUF5132, Protein of unknown function (DUF5132). Proteins in this family are uncharacterized, but have been identified as members of a gene cluster for the synthesis of Ansamitocin.	6.30224e-08
NC_011726.1\|WP_012596250.1\|3107938_3109273_+\|TRAP-transporter-large-permease-subunit	gnl\|CDD\|227010	COG4664, FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component [Secondary metabolites biosynthesis, transport, and catabolism].	3.58333e-167
NC_011726.1\|WP_012596240.1\|3090065_3090242_-\|hypothetical-protein	gnl\|CDD\|369567	pfam07878, RHH_5, CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5. This family contains bacterial proteins that form a ribbon-helix-helix fold. This fold occurs in many examples of bacterial antitoxins.	2.71944e-16
NC_011726.1\|WP_012596246.1\|3101441_3103424_+\|hypothetical-protein	gnl\|CDD\|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	0.00119402
NC_011726.1\|WP_012596256.1\|3116037_3116967_-\|ornithine-carbamoyltransferase	gnl\|CDD\|234835	PRK00779, PRK00779, ornithine carbamoyltransferase; Provisional.	0
NC_011726.1\|WP_012596253.1\|3113119_3114352_+\|methionine-adenosyltransferase	gnl\|CDD\|237106	PRK12459, PRK12459, S-adenosylmethionine synthetase; Provisional.	0
NC_011726.1\|WP_012596254.1\|3114582_3115677_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173845	cd01156, IVD, Isovaleryl-CoA dehydrogenase. Isovaleryl-CoA dehydrogenase (IVD) is an is an acyl-CoA dehydrogenase, which catalyzes the third step in leucine catabolism, the conversion of isovaleryl-CoA (3-methylbutyryl-CoA) into 3-methylcrotonyl-CoA. IVD is a homotetramer and has the greatest affinity for small branched chain substrates.	4.10426e-19
NC_011726.1\|WP_012596238.1\|3084484_3085645_-\|restriction-modification-system-DNA-specificity-domain-containing-protein	gnl\|CDD\|341150	cd17261, RMtype1_S_EcoKI-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit TRD-CR, similar to Escherichia coli str. K-12 substr. MG1655 S subunit (S.EcoKI) TRD2-CR2, Escherichia coli A58 S subunit (S.EcoEI) TRD2-CR2, and Aminomonas paucivorans S subunit (S.Apa12260I) TRD2-CR2. Escherichia coli str. K-12 substr. MG1655 S subunit (S.EcoKI) recognizes 5'... AACNNNNNNGTGC ... 3', Escherichia coli A58 S subunit (S.EcoEI) recognizes 5'... GAGNNNNNNNATGC ... 3', and Aminomonas paucivorans S subunit (S.Apa12260I) recognizes 5'... GCCNNNNNCTCC ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. For example, S.EcoKI-TRD1 recognizes AAC/GTT and S.EcoKI-TRD2 recognizes GCAC/GTGC, S.EcoEI TRD1 recognizes GAG/CTC and S.EcoEI TRD2 recognizes GCAT/ATGC, and S.Apa12260I TRD1 recognizes GCC/GGC and S.Apa12260I TRD2 recognizes GGAG/CTCC. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases.	2.11825e-76
NC_011726.1\|WP_012596245.1\|3097066_3101347_-\|hypothetical-protein	gnl\|CDD\|379049	pfam13173, AAA_14, AAA domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.000259484
NC_011726.1\|WP_012596243.1\|3095697_3096588_+\|ATP-binding-protein	gnl\|CDD\|379165	pfam13401, AAA_22, AAA domain.	3.28745e-23
NC_011726.1\|WP_012596248.1\|3106018_3107158_-\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270400	cd13682, PBP2_TRAP_alpha-ketoacid, Substrate-binding component of an alpha-keto acid binding Tripartite ATP-independent Periplasmic transporter and related proteins; contains the type 2 periplasmic-binding protein fold. This subgroup includes TRAP transporters that bind to ketoacids such as pyruvate and alpha-ketobutyrate, xylulose, and other unknown ligands. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	0
NC_011726.1\|WP_012596255.1\|3115685_3116018_-\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|212139	cd11532, NTP-PPase_COG4997, Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from archaea and bacteria. The family includes some uncharacterized hypothetical proteins from archaea and bacteria. Although their biological roles remain unclear, the family members show significant sequence similarity to the dimeric 2-deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTP pyrophosphatase or dUTPase) and NTP-PPase MazG proteins. However, unlike typical tandem-domain MazG proteins, the family contains a single MazG-like domain.	2.22645e-36
NC_011726.1\|WP_012596237.1\|3082403_3084482_-\|N-6-DNA-methylase	gnl\|CDD\|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	1.19016e-20
NC_011726.1\|WP_012596239.1\|3087314_3089942_-\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|226581	COG4096, HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	5.92702e-135
NC_011726.1\|WP_157861331.1\|3093696_3095691_+\|DDE-type-integrase/transposase/recombinase	gnl\|CDD\|378147	pfam09299, Mu-transpos_C, Mu transposase, C-terminal. Members of this family are found in various prokaryotic integrases and transposases. They adopt a beta-barrel structure with Greek-key topology.	5.66063e-09
NC_011726.1\|WP_012596247.1\|3104860_3105925_+\|uroporphyrinogen-decarboxylase	gnl\|CDD\|215237	PLN02433, PLN02433, uroporphyrinogen decarboxylase.	0
NC_011726.1\|WP_012596252.1\|3109993_3112984_+\|cation-transporting-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0

>NC_011726.1|WP_012596246.1|3101441_3103424_+|hypothetical-protein
MTHITVVQCRLIAPESTLQHIWKMMAQQQTPLINQLLHDINTHPDINTWLTANQLPSKLVETLAQPLKTQSPYQGLPGRFITSAIILVKEMYASWFAIQTQKRLSLEGKKRFLTILKSDKQLIQDSQTDFLTLCYKAQQLLKRTQNKLKLDEPQHSEKAHWSIINALYPAYNNAKTPISRAAFALLIKNNGQVPDTPENPDYYQQRRKRKEIQIRRLEEQLKASLPKGRILDSKHWENTLKLAQTPITTIEEITSLQTQLLQKYSHLPFPVFYGTNTDLTWFKNPQGRICVKFNGLNQYPFQIACNKRQYPWFQRFFTDYQSYKSHKQQVPTGLMVLRSARLLWQPTNGQGEPWNTHHLSLHCAIDNDLWTISGIQQVKQQKILQTEQKIANFHSKALEKELTPNQQQRLKASQTSLNLLKTFDINEFFPSKCSLYQGSPDIILGVSIGLENPATIAIINISTQEILTYRTTKQLLSRTRKVRNKKPNSNNSNQSLSSAYKQISNYELFLQYQQQKHHNQHQRHNAQINDANNNYGEANLGLYLNRLLAKAILELAQQYQVSLIILPSLKNKRELIESEIRAKAELKYPGCKEKQDSYAKDYRTNVHQWSYQQLIKCIESKAAQIGIDTATGKQMNLETSQDQARNLVLNFCQKFSPTQV
>NC_011726.1|WP_012596245.1|3097066_3101347_-|hypothetical-protein
MSSFSHSDATPTYRGYRLQLLYTLWRILSENKKNNFTFQPEGQEDLAIYDEAGHLIEIIQVKARSENISLSSFSPKKVDSFFNRSHILINSTSSLKTIRVISFGCFGQDFEEACNGNINKLKAESEKLSNYGHLSSEEAEKLLKKINLETVTEENLEKEALGLLKQGLAGIDYKCAFDIITYWLYICAENQIKITYQSITEKLNKIGEFLVERTTYHKEWFTSILPIENNFIDEQKKEYLSHEFYRGISARYEHILANVDVIRKNELEKISQEFNRNKVVIIHGASGQGKTTLAYRYLHEFHPEQWRFKIQLIENRQHSLSIARAIEGYAKAIGIPIIMYLDVSHNDNGWTDLVKQLASYQNIYVLVTVREEDYRRASVSGTEFPFSDIELTFDANEAKEIYQSLVEKKATVEFLNFEEAWDRFYQEHCFHEKLLMEFVFLITKGQFLKQRLLQQVRRLEDEVRIGKFSNKELEFLKLVSIASAFEARLDVKSLVKFLNLPVPRRTIELLEKEYLLKCSDDGSLIYGMHPIRSQILSDILTDPSLSAWSESAIECFPFIIESDMESFLLYSFSRKYNEIRPLVNSLMFYQPKYWSGIAGINKALIWLGIKDYVEENKALIQTLHSDLGSGFWILLSYDITDAMTDSESSIWQCLRTIVPESYVNEIENLQSQQTDKSKVFQYSKKWLSNIIFIIEQPFGYLDWQAMSEVFFWLGRLQIDFCLDNLINKIDFNNLFQDLPIDVLADLILGLSFGYEEKFNIWMNTHRMQIVQRFRQETQTIILEDDNQKLTAHFLIPTYARKNENSFNNSIKREDESELHQEAMWRIDLLRKLLPDRQLYACCGYGHRMFTEELPYDETVKTGIAKENLPVTWLTSINSTFTGIADQFFKPQNWSEYSTQVIRLRTNILNMLGKLDKGLINYFRQSQAFNWFDKYINPPEWRDCKQQLVYTPLLPACSANEWGFNNKNDLFLSNKNNALAFQDYSSYLKVFREYHQNLYNFFNQAEQGMVITSALGRKEDKERVLEIAKSNNLDPKLSHIAAHNLANTLKGLKRFQQEFRRKFSSYLDLEKLKTLESKELETFNNLCCLWLFFAFYPGKHFQDPIKECHKEITDKLKKIRNKLKKEFCKISNNNLSVQILSENVLWEHDKTLWITIDGSNPIEVYIHIVVVIKLLTQAINVLGNTPLRRYILDLNWTYVAIIPLVKGKSLQGTASHIYIHTLVYRDEEELNWWNYAQKEIPKDAISHLSIERHAEYLLKNPNHFLTSFTSLKFLLAHIKDLNRMPKNQIDNFAFKQLKNYFDELEESWLKILDFSYNSLERLENLKEETSLDNLQKYDLSKDNLEEFINILKEIFFSLQNLTKTTAETILLGDTQNIDNIFSTICTWSHTLEQVENYIFLIYFIWIAEILDNSNNIIEFNHASVLSS
>NC_011726.1|WP_012596244.1|3096594_3097095_+|hypothetical-protein
MGKSEAKFQPPWYVEPYEGESISHYLGRYCRHESVSLSALGKATGLGAILGRWEKFRFIPFPSEEELEAFGELIGLSVAQLKGMLPQESMKLLPIRLCGLCYSQKPYHRMEWQYQSRLNCTVHGVKLLTKCPSCGERFAIPSRWVEGKCLRCGMGFKSMRKEQKHD
>NC_011726.1|WP_012596243.1|3095697_3096588_+|ATP-binding-protein
MAKGNLEQLKVSAKTQSEEVNGRSAAQKAEIERIGQADTYCPLSRDEELFTWLNDQRDLRLCGYIMATRGSGLPKACEYYRMAHVKRRGSLFEMPATVFYVEMLQKGKATDLYRAILGEFGHPLSNLGTLRHLRSRTWDNLKRYGVKILIIGKADYLKLEAFNELIDLYDHSRISVILAGTHYLEDILGRNHPAYVNLCNSFLEWYEFPGLSSKDVGIVVEHWEKTFLSPKYRLNLTQYPEIVETLTEKSGGLIESLYDILRQIAMFKVDDPDFELTPSNVLAYLSHRKPPTLKLG
>NC_011726.1|WP_157861331.1|3093696_3095691_+|DDE-type-integrase/transposase/recombinase
MSKSNITSHKTEINREEQDLEQTESQKSHQNHLKLINTQLSPATEEIINALEPILQASNTKQRTQAIEKASQMLGKSTRTIRRMLAKMTHEGVATLIRGRQDKGQYRISKQWRDFIIKLYKWGQQDGSRQNISQIYNALIALEAQGEKLRTQMNKKDGYAKLLKPYPEVLEDLIAGKYPSHPTVYKVVRDELERKNKSKARHPGADIDHQVVQTIEENLYITHSNQIWQADHTKLDVFVFESISKENPSAKQEVIRDSKGEPIRPFLTVIIDSYSGCLMGYYLGFVAADSHRVALALRNAILPKQVKEKYGLQNEWEQSGIPEYLVTDRAKEFKSHHAKLIAMQLGFQWKLRAFPSAGGLVETIFNQTNNEVLKSLPGYTGKNVQERDNNVEDHVCMTFEELERELVQYFVDHYNQHHYPKAKIDPQFEVHRRANRWKYGLISEAEIIDERSLDICLLKQAHRKVQKYGTIQFETMIYMGNCLKDYIGEEISLRYDPRNIVTLLAYTAPKNGEPSEFIGVIKARHFEYEQMTFDELKWIIHKLRSQSKDPENISILNERYNHLNFIAKKRTEKGRRSKKAQDKRDQVTNQSTLTEIFPENAPQPNNNSEIVSEEATKTVKMGRKSKKRIITQPLPPETNARVRRRSSGIMTNIQDWNEYKKNNW
>NC_011726.1|WP_012596241.1|3090391_3092440_+|hypothetical-protein
MTLKTLECRLYAPSDTLRYLWLLMAEKNTPLINEIINHLSEHPDFDQWFKAKQIPKSAISDICNDLKSQENYQNQPGRFYSSAISLTHYMFKSWFAVHKQLQRRIEGKRRWLNLLKSDQELEQNCGQSLEIIIQKAEEILKLMDSEKSQSSSKPKKPKKPKKKKKSSSEETITLFDRLFKAYNQGNDSLESYALAYLLKNNGQIPEDDEDLDKFALRKRKKEIEIERLQQQLENRIPLGRDLTGELWQEMLTIVNESIPQDENEASAWQAKLLKKSHNIPYPVAYETNTDLKWSKDSRGHLLVTFNGLVESLKKLNLNPEFEIRCDRRHLPWFQRFCKDQEIKANNDQHSSALFVLRSARLIWREGQGKEDPWKIHQLYLQCSVETQLWTEAGTKQVQSEKMVEFQLNQLRMKPELTFPIFFRSQSLPTYFNLWKVITSYRILKFLEKGDFTKAQKNFQDAIKRTESCLENLQSSYLTSQKSLYQGNPEIIMGVAMGLSQPATIAVVNVVTQEVLTYRSLKQLLGKNYNLLNRQRQQKQKLSHQRHKAQKKDAFNQYGESELGQYVDRLIAKAIVQVAKEYQADSIAVPKIRQMREIIQSEVQARAERKIQGYKEGQKKYAQQYRENVHQWSYGRLIESIHQASAKFGIRVEIASQSYQGSFQEQAQNLAIAAYTNRLEAVG
>NC_011726.1|WP_012596240.1|3090065_3090242_-|hypothetical-protein
MSKRVYLTLPDKVYEALERWADEQGRPVANLAAYLVERAVEKAESEGKIPLNKNNPKT
>NC_011726.1|WP_012596239.1|3087314_3089942_-|DEAD/DEAH-box-helicase-family-protein
MTSYNEADTRAKLIDPQLKLSGWGENQIEREHYFAKRQQITAGRIYLVGDQSRRRQPCRVDYLLRYQGQAIAVLEAKDESHSVDAGLEQAKAYARKLDLPFAFASNGHSFIEFDFFSSCSQELSTFPTPQQLWQRWETYRQGKVKSGRVAENGGNYGVLSVNPLLYPVCPESQCGKVPRYFQEVAIRRVIERILKQQRRILLTMATGTGKTFTAFQIVWKLKQSGWLRKPILFLSDRLILRDQSYNTFAPFVAPSADPRGVIEKGKFNSNRELYFALYQALDALKEGESLFSQIPADFFGLIIIDECHRSGFGKWNGILQHFTGAIQLGMTATPKQDESIDTYAYFCAEESEIPLDPDDNSKGTWKPPAYQYSLGQGIDDGFLATYKVHKVRTTVDKNGLHLQEARIQGAEIYIPEDVEPRQQYLTGQFEREITLPDRTKTMVSHLAGLLRQFGEREKTMVFCVDMTHARLVARLLQNEFAELGYSNYAVPIVSEEGEAQAWLEQFQDSDRLTPIVATTAELLSTGVNVPSCRNIVFMKPISSPILFKQIIGRGSRIDPATGKEWFRIIDYVGASRLFDQWDRPIGELPQAITGARTSIIEGRVIHGDTEEFLVGASVSALIGVNQQLSPILTDDNGYFRLEALPAGKIRLFLRGNGFRSREITLETAENETLTVVLALNSVKPPVGKIRVEGLEVTIADEVTFIVDATGEQLTLAQYLDYTKAKIRGYVPNWSQLHQIWIDSEQRKLLLRELTTASVYIEVLGEVLAQPKADQFDLLAHIAFNKPIHTRDERVEAFLNYEQWYLEAQTEEAREVILGLLDKYRLAGIEEIVNPEVFRLSPFQEMGQIKGVILRLGTMENLRQIFREIQQKLYRQ
>NC_011726.1|WP_012596238.1|3084484_3085645_-|restriction-modification-system-DNA-specificity-domain-containing-protein
MSDESQKFIKLGNLIKFKYGKSLPNRERDPDGKYLVFGSGGKIGLHNSYLTESPVIVVGRKGSIGSTFYSDNPCWCIDTTYYVDQFSSNLYSKYLYYFLNTLKLDRLNRAATIPGLSRDDLYTFSIPIPYPNNPKLSLDIQQRIVARIESLFGEIKRNRLLLEQMRLDNDLLLPNALDEVVERLDSKRQTLLDVIQEKPRNGWSPKCDNDPNGVPVLKLGAVLRFQYNPDEIKRTSLPTDENAHYWLEAGDILISRSNTLDLVGHASIYSGIPYPCIYPDLIMRFRVNPNKADSKFLMYWLQSKEVRHYIQTNASGASPTMKKIKQETVCNIPFPIISLEEQSYFAYHLDAIQQEVNKINRIIEEDEQNFKYLEQAILEKAFRGEL
>NC_011726.1|WP_012596237.1|3082403_3084482_-|N-6-DNA-methylase
MTIAENLNKIWSEFRQFGITDDLVVIEYLARLLLEKVLDISQSNIGIHFDGMWPTYYQVMGFLTDLPLYQLYSSAELQSIIDTVTNLVPISTLPRHPKDIRNLNLELIQENLKNAINEVENIPNLFNHYILFRLSTRQSGGRYPTPRHITQFIFNLAQIEPHHSLADFACGSGGFLVERELTIDNYSKTWGIDISPEWIRLAYTNIALKKFPPQLGSGNAINVANSDDWKDRVCDRILMNPPFGEKIDSKLATENLGKNVGSRSETALTTLAIQKLAEDGIAGILVPSGLLFSNSKAERELRQTLIDDYHLKAVITLPKDALQPYSSLQSHLLLIHRFPSPNLGEGLGVRETWFFQLEEDGYSSGRSRDLTQKPDLSKSDFPFVEKVFKRQGDEFDYFFPDSHPEIGIKVIKNDENELLGFVFEGRETEINFVTFYPSPSPSTSPFLLIDTLPIDNPKLSIKIPLDGSEVNIIENPSQYLNDLFKPTKNNPIPETRLYSQPVKGIAIAFNSDTIITKENLRILGILIPSNQVINRNYDLRPEEYIDKPLETRLNNSPVELLTRIYSNQRQLTQNLETLFSRIELPSISTEKLPSPIVDTFTPIGKFNPQQQTIWDKIQRQTESYTDDNGDNYEIALHFTPQDIESEDNDEISDITQRTLELLEAMGVIIPVTLHNKLYYRRVTQRDLWTNSD
>NC_011726.1|WP_012596247.1|3104860_3105925_+|uroporphyrinogen-decarboxylase
MTQGNNTPYLLRAARGEILDRPPVWMMRQAGRYMKVYRDLRDKYPSFRDRSENADLAIEISLQPWKAFRPDGVIMFSDILTPLPGIGISFEIPESKGPMIDSPIRTQEQVDNLHSLDPEASLPFIKTILKALRDEVKNEATVLGFVGSPWTLAAYAIEGKSSKDYANIKRMAFSEPAILHQFLSKLADAIAVYVRYQIDCGAQVVQLFDSWAGQLSPQDYKVFALPYQQQVVRQVKATHPDTPLILYISGSAGVLELMGQSGVDIVSVDWTVDMADARQRLGRNMMVQGNIDPGILFGSKQVIRDRILDTVQKAGKGGHILNLGHGVLVGTPEENVGYFFETAKQVDQLLAVPV
>NC_011726.1|WP_012596248.1|3106018_3107158_-|TRAP-transporter-substrate-binding-protein
MKRRNLVKATSQGAIAATVAGIAIGCSKSQNQATSNNTELPKITWQMATSWPLSLDTIFGGATVFAERVAQMSGGRFKISPKPAGDLAPPLEVLNVVKQGAVPCGHTAAYYYIGQNPAAAFGTAVPFGLTAQQQNTWLYEGEGLKLLQELYASQFGVIQFPAGSTGTQMGGWFRKEVSTINDLKGLKMRIPGLGGQVMSKLGVLVQNLPGGEIFQALQTGAIDAAEWVGPYDDEKLGLNKVAQYYYYPGWWEPGPTLEVQINLNAWKKLPVEYQQMIQTAAFEANQIMLARYEARNYEALQRLLQSGTQLRPYSDEILNAAKTSAFELYDEFAAKNADFKAIFENWQKFRDGVFTWSNLNQGSFERFVYKTLDTPSQGS
>NC_011726.1|WP_012596249.1|3107233_3107827_+|TRAP-transporter-small-permease-subunit
MPTLFKFAQTIDYLTEQVGRLLYSIVILTVGIGFYNVAARYLGRFVGLKLSSNALIELQWYLFSLMFFIGFPYILKHSANVRVDFLYAHWSPKRQALIDFLGTVLFLIPFCLIGIYVTFNPVLQSWGQLPDGSWGAWEVSSDADGLPRAPIKSMILVSFALLLLQAISQAIKYGAILQGYEPALREIQSETEKPPIE
>NC_011726.1|WP_012596250.1|3107938_3109273_+|TRAP-transporter-large-permease-subunit
MGFEWLAIAMFVGFFFILISGYPVAPAFAGTAIIFGLMGLAVGAFDINLLLLLPNVWFQTMSNFTLLAIPFFVFLGVVLEKSGLAEELLETIGIVLGPLRGGMALAVIIVGTLLAATTGVVAATVIMMGLLSLPVMLRYGYDKRLAAGVIVASGTLAQLIPPSLVLVVLSDQLGVSVGDLFLGALIPGLMLSASYAIYVLVLAFLYPNVAPALPLEARRVQGKALIKQVIKAVLPPCLLILAVLGSIFFGIATPTEAGAVGAVGACFLAASKGRWTQNLIKDAAHDTAVVTSVVLMILFCSSFFSIVFNGLGGKELITQFLLNIPGGYISFMIVSNLVIFILGVFLEFIEICFIALPLLVPAAQALGIDMVWFGVVIAINLQTAFISPPVGFSLFYLQSVAPKEIPTTDIHKSALPFMLLQGLILIVVIIFPQTVRWLIDISYN
>NC_011726.1|WP_012596251.1|3109442_3109742_+|DUF5132-domain-containing-protein
MALKDFVPHLDLKDIAEDLGIPGITAIVLLPVLIPAAGKAAKPLAKATIKGGIILYEKGKGVIANVGETLEDLIAESLAELAEETSEKAAIAEADVMAN
>NC_011726.1|WP_012596252.1|3109993_3112984_+|cation-transporting-P-type-ATPase
MKRPNSIDCHQPRETSFVKILHGTVKGRGRYKVQGLFGSNPLKRYLEFNLSLRKGIKTVQANPNTGNILLHFHKDKTTQEIAILIDSLVQDYYRSPKEFAQLFYQQTMVILNTSVPWHLKEIDTIVAELNTSTERGLSHADAQTNLRQYGSNALTEAEPRSGLSIFLDYFKSVPVALLSGAALLSVLTGGIADAIVIMGVVSINAILGYVTESNSERIINSLKHFINPSAWVLREGQLIEINSQDLAVGDILLLQPGSYVPADARLIEADRLSIDESALTGESLPIRKHQEILASPQETIPLAERKNMVYRGTFVTGGQGRGVIVSTGNSTEMGQIQSLVGETSQPSTPMERQLEQAGSQLVLLSSVVCALVFAIGLLRGYGLLEMVKSSISLAVAAVPEGLPTVATTTLALGILNMRKQKVLIRRLEAIEALGSIQALCLDKTGTLTANRMTVLKVCWDGRETKLADGHFWVDNQEINPYSCDELLKLIHIAVLCNDSQINTHQDGTYIIDGSATENALIEMAIAAGVTVADLNHKYPRLLTYHRSTEHNFMATVHRIHESAYLMAVKGNPSEVLDRCSTQMRNGQPVELTEADRQAIEEQNESLAGQALRVLGIAYSQGETADIESLPVSNLIWVGLIGMADPIRPGVTETIADFHTAGINTLMITGDQSPTAYAIGKELNLSQGQPLKILDSTELTDLSPDVLAGLSEQVHIFARISPAHKLQIVQALQQRGLVVAMTGDGINDTPALKAAEVGIAMGHTGTDVAREVADVVLEDDNLQTMIIAVSQGRTIYNNIRKSVHFLLSTNLSEIIVMLFATTGGLGQPLNAMQLLWLNLVTDIFPGLALALEAPEPDVLTLPPRSPDEPIIKSSDFRRIVWESTALSVSSLAAYGYGIARYGISPHASTIAFMSLVSGQLLHALSCRSSRPLRSQQLPPNPYLTGALAGSMGLQWVSLATPGLRNLLHLTPLNLADSLVIGGSAILPLIINEGTKPQ
>NC_011726.1|WP_012596253.1|3113119_3114352_+|methionine-adenosyltransferase
MKKDFMFISESVTQGHPDKLCDQISDAIVDHFLRHDPYSRVVTECAVSTAIVFIAARFQSDAMIDFPKIARQVIKQVGYEESSFSAKTCSIVTSLQEVASMNDRYVDERQLSDEEIEAIPVKNQATVFGFACRQTPALMPLPIWLAHQLAKRLTQVRQDNILSYLTPDGKTQVGVEYRDRLPYRLQSITVIASQDSSSIAKSPNFQQFQQDIRETVIDAVFADDSLLIKPDQETQIFINPDGPLLVGGPAVHSGLTGRKNAIDTYGEYSRHSGAALSGKDPTRIDRIGAYAARYAAKNLVAAGLADECEVQLSYSIGIARPISIQVQTFGTGKVPDEMLTEILEKHFEFRLAGIIKQFNLRFLPSLIKGGFYRKLAAYGHVGRTDLGVIPWEETNQISLLHDCANKAYIF
>NC_011726.1|WP_012596254.1|3114582_3115677_-|acyl-CoA-dehydrogenase
MQTKIAPQNNTEESLLSSAQTYFIQQVAPQAALLDQDTEALKQSFKKMGDHGLLGLNIPQQWGGKGASELTYRRFQILIARYSGALAFLQTQHQGAIAKLIVSPNTPLKQTYLPLMATGEMLVGVGFSQLRRQGKPLMQATPVTGGYLLTGEVPWITGWNIFEEFIIGATLPTSEALYGIIPFREEPGLHFSQPMELAVMGVTNTVKATLTDWFLPCDRLVSLHPPGTVQESDRKNVLHHGFFALGCAQAGLDILEQACQQKSLPFLQPALDSLHNELMQCTQGMLASLSPDRVLYEKRLQLRGWAINLASRCSQGAVIASSGGANFLSHPAQRVYREALVFTVLGQTSEVMEETLKQLVSEEF
>NC_011726.1|WP_012596255.1|3115685_3116018_-|nucleoside-triphosphate-pyrophosphohydrolase
MRQYHHKLVRDKIPDIIAKSENFCEIRTLSEQEYLEALKHKLLEEAQEVIEADPENLVKELGDLFEVIDNILIAYQISRETVINYQQQRRKERGGFTQRIQLIWTETQAQ
>NC_011726.1|WP_012596256.1|3116037_3116967_-|ornithine-carbamoyltransferase
MSMNTLKGRDILGIADLSASELTEILELGALLKSGERSPVCQKVLGLLFSKASTRTRVSFSVAMYQLGGQVIDLNPSVTQVGRGEPLIDTARVLDRYLDILAIRTYQQEDLETFAKYAKIPIINALTDWEHPCQILADLMTIKECFGTLSGITVTYLGDGNNVAHSLILGGALMGMNVHIATPKDYQPNQAILDKAKEIGVEGFQVLVTDNPIEAVEGSQVLYTDVWASMGQESSAEARIPLFEPYQVNQKLLNHADQEAIVLHCLPAHRGEEITDEVIEGKQSRVWDQAENRMHAQKALMVSLLGVDS

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Crispr_ID: NC_011726_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_10

4328521-4331328

TypeV-U2

V-U2

Consensus_repeat	Method
GTTTCAATCCC-----------ATTGCTAGGATTCATTAATAAGAAAC	PILER-CR
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CRISPRCasFinder
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CRT

38 spacers

c2c8_V-U2

The CRISPR arrays of NC_011726_10

>merge|NC_011726|10|4328521-4331328|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACATTAGGCGAGTTTTTTGACTTCTTGATGATAGCACGGGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACGTTTGAGATTCTAGGATTGGGGGGAAATTGTCTTGGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTACACATAATACTTTTTATGCTTCACAAATTATCAACGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTCAGCTCTTTGTCTGATTTCTTGTCTTTTCCTGTTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTCCATATTATTTGAAAAATCGATAAACAATCGCAATGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACAAATCGTTATTGTTATGCAAAATTTCTTTGCCCTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTGTTTTGACAATAACTGTATTGAAACCATTAGTTATCGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTTTTTCAGCCAATTTTTGACTCTTGAAGTCCGGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTCAAAGGTTGTGACTTTTACCGTAGGAGAAGTCTTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACAACGCAAACAAAACCGGGGACACGATCGAATGCCGAGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTGGCTTAATGTAGTATGTTGTGGCCACGACACAGCTTCGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTATGGCATCAAGTTCATTGAGACTGAAGAAAGCTAGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACCCATCAATAAAAGGCTTAAGTTTTCCTGCCAAGCCGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACGCAACAATTTCAGAACGTCCTAGAGATTGGAGTGTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACACATCTGCTATTGATCAATGGAGTGTTAACTGGATTTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTGCGATCGCATAACAACAAAGGAAAAATTATGATTATGTGTTAACTGGATTTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACGAAAAAAACAACCACAGGAAAGATTTATATCAATCCGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACGCAACCGTTACCAACGGGAAAGAATATTGGTATGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACCATTTGTTTTGTCAAAGAACTTCAAAATGGACAAGCTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACAAAGCCGAAGATGCCCAAGATTTTGTCGATAAACGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTTTTGATCGCGTACGAATCAAGGATATTATGGGCGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACACAAAACACAGGTGGGGGTGCAGGAAGCACAACAGAGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTGTGACGCAATCATTCAGAAAATCAAATCTATAGAGGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACAATACCTTAAATAATCCTTTGATTGATCCATCTAGTCGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTAAAGAGAATAAGGACGATCCATCCAATCGGCTAAATGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTTTTATGGCAACGGCTTTATCTTTTAAGGATAAAGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACAGTAACGGTGGTTTTGCCGTCTTCATCGGTAACAGTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACCTAGACGTTACAGCGACATTCAACGAGCAGGGGAAGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACACCAATCCCCTCCCCAAGATATAGCAAAAATGGATCGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTTATTGTCTACCGTTACCTATGGAGATTGAGCTTATGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACGTAACGCTCCCCCAATTAATCCAGCCCCAACTGTAATGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACCTTTAGCTGTTTTTGCAGGTCGTTTAACCGCTTTTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACAAAGCCAGCCCAGTCTATCGAAGCTTAATCATTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACCTGTTGACGACGACCAACGCCGTCCAAATTGTGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACTAAAAATGATCTGTTGTTTCCCGTCCGGTCCACGAGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACAAACGCAATTTTAAGCCCTTGGGGACTATTGTCTAGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACACTCAAGCCATTAGACCTGTGGGAATAATTGGGCAAAGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAACGGCGAAAATGAAGACGACGACGATGTGGTGACGGAAATGTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC

>NC_011726|10|7|4328521-4331328|PILER-CR
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ATTAGGCGAGTTTTTTGACTTCTTGATGATAGCACGG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GTTTGAGATTCTAGGATTGGGGGGAAATTGTCTTG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TACACATAATACTTTTTATGCTTCACAAATTATCAAC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TCAGCTCTTTGTCTGATTTCTTGTCTTTTCCTGTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TCCATATTATTTGAAAAATCGATAAACAATCGCAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAATCGTTATTGTTATGCAAAATTTCTTTGCCCT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGTTTTGACAATAACTGTATTGAAACCATTAGTTATC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTTTTCAGCCAATTTTTGACTCTTGAAGTCCG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TCAAAGGTTGTGACTTTTACCGTAGGAGAAGTCTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AACGCAAACAAAACCGGGGACACGATCGAATGCCGA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGGCTTAATGTAGTATGTTGTGGCCACGACACAGCTTC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TATGGCATCAAGTTCATTGAGACTGAAGAAAGCTA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CCATCAATAAAAGGCTTAAGTTTTCCTGCCAAGCC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GCAACAATTTCAGAACGTCCTAGAGATTGGAGTGT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACATCTGCTATTGATCAATGGAGTGTTAACTGGATTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGCGATCGCATAACAACAAAGGAAAAATTATGATTATGTGTTAACTGGATTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GAAAAAAACAACCACAGGAAAGATTTATATCAATCC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GCAACCGTTACCAACGGGAAAGAATATTGGTAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CATTTGTTTTGTCAAAGAACTTCAAAATGGACAAGCT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAAGCCGAAGATGCCCAAGATTTTGTCGATAAAC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTTTGATCGCGTACGAATCAAGGATATTATGGGC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACAAAACACAGGTGGGGGTGCAGGAAGCACAACAGA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGTGACGCAATCATTCAGAAAATCAAATCTATAGAG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AATACCTTAAATAATCCTTTGATTGATCCATCTAGTC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TAAAGAGAATAAGGACGATCCATCCAATCGGCTAAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTTTATGGCAACGGCTTTATCTTTTAAGGATAAA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AGTAACGGTGGTTTTGCCGTCTTCATCGGTAACAGT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CTAGACGTTACAGCGACATTCAACGAGCAGGGGAA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACCAATCCCCTCCCCAAGATATAGCAAAAATGGATC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTATTGTCTACCGTTACCTATGGAGATTGAGCTTAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GTAACGCTCCCCCAATTAATCCAGCCCCAACTGTAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CTTTAGCTGTTTTTGCAGGTCGTTTAACCGCTTTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAAGCCAGCCCAGTCTATCGAAGCTTAATCATT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CTGTTGACGACGACCAACGCCGTCCAAATTGT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TAAAAATGATCTGTTGTTTCCCGTCCGGTCCACGA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAACGCAATTTTAAGCCCTTGGGGACTATTGTCTA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACTCAAGCCATTAGACCTGTGGGAATAATTGGGCAAA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GGCGAAAATGAAGACGACGACGATGTGGTGACGGAAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC

>NC_011726|10|9|4328521-4331328|CRISPRCasFinder
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ATTAGGCGAGTTTTTTGACTTCTTGATGATAGCACGG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GTTTGAGATTCTAGGATTGGGGGGAAATTGTCTTG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TACACATAATACTTTTTATGCTTCACAAATTATCAAC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TCAGCTCTTTGTCTGATTTCTTGTCTTTTCCTGTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TCCATATTATTTGAAAAATCGATAAACAATCGCAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAATCGTTATTGTTATGCAAAATTTCTTTGCCCT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGTTTTGACAATAACTGTATTGAAACCATTAGTTATC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTTTTCAGCCAATTTTTGACTCTTGAAGTCCG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TCAAAGGTTGTGACTTTTACCGTAGGAGAAGTCTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AACGCAAACAAAACCGGGGACACGATCGAATGCCGA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGGCTTAATGTAGTATGTTGTGGCCACGACACAGCTTC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TATGGCATCAAGTTCATTGAGACTGAAGAAAGCTA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CCATCAATAAAAGGCTTAAGTTTTCCTGCCAAGCC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GCAACAATTTCAGAACGTCCTAGAGATTGGAGTGT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACATCTGCTATTGATCAATGGAGTGTTAACTGGATTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGCGATCGCATAACAACAAAGGAAAAATTATGATTATGTGTTAACTGGATTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GAAAAAAACAACCACAGGAAAGATTTATATCAATCC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GCAACCGTTACCAACGGGAAAGAATATTGGTAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CATTTGTTTTGTCAAAGAACTTCAAAATGGACAAGCT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAAGCCGAAGATGCCCAAGATTTTGTCGATAAAC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTTTGATCGCGTACGAATCAAGGATATTATGGGC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACAAAACACAGGTGGGGGTGCAGGAAGCACAACAGA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGTGACGCAATCATTCAGAAAATCAAATCTATAGAG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AATACCTTAAATAATCCTTTGATTGATCCATCTAGTC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TAAAGAGAATAAGGACGATCCATCCAATCGGCTAAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTTTATGGCAACGGCTTTATCTTTTAAGGATAAA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AGTAACGGTGGTTTTGCCGTCTTCATCGGTAACAGT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CTAGACGTTACAGCGACATTCAACGAGCAGGGGAA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACCAATCCCCTCCCCAAGATATAGCAAAAATGGATC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTATTGTCTACCGTTACCTATGGAGATTGAGCTTAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GTAACGCTCCCCCAATTAATCCAGCCCCAACTGTAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CTTTAGCTGTTTTTGCAGGTCGTTTAACCGCTTTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAAGCCAGCCCAGTCTATCGAAGCTTAATCATT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CTGTTGACGACGACCAACGCCGTCCAAATTGT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TAAAAATGATCTGTTGTTTCCCGTCCGGTCCACGA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAACGCAATTTTAAGCCCTTGGGGACTATTGTCTA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACTCAAGCCATTAGACCTGTGGGAATAATTGGGCAAA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GGCGAAAATGAAGACGACGACGATGTGGTGACGGAAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC

>NC_011726|10|5|4328521-4331328|CRT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ATTAGGCGAGTTTTTTGACTTCTTGATGATAGCACGG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GTTTGAGATTCTAGGATTGGGGGGAAATTGTCTTG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TACACATAATACTTTTTATGCTTCACAAATTATCAAC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TCAGCTCTTTGTCTGATTTCTTGTCTTTTCCTGTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TCCATATTATTTGAAAAATCGATAAACAATCGCAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAATCGTTATTGTTATGCAAAATTTCTTTGCCCT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGTTTTGACAATAACTGTATTGAAACCATTAGTTATC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTTTTCAGCCAATTTTTGACTCTTGAAGTCCG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TCAAAGGTTGTGACTTTTACCGTAGGAGAAGTCTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AACGCAAACAAAACCGGGGACACGATCGAATGCCGA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGGCTTAATGTAGTATGTTGTGGCCACGACACAGCTTC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TATGGCATCAAGTTCATTGAGACTGAAGAAAGCTA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CCATCAATAAAAGGCTTAAGTTTTCCTGCCAAGCC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GCAACAATTTCAGAACGTCCTAGAGATTGGAGTGT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACATCTGCTATTGATCAATGGAGTGTTAACTGGATTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGCGATCGCATAACAACAAAGGAAAAATTATGATTATGTGTTAACTGGATTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GAAAAAAACAACCACAGGAAAGATTTATATCAATCC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GCAACCGTTACCAACGGGAAAGAATATTGGTAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CATTTGTTTTGTCAAAGAACTTCAAAATGGACAAGCT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAAGCCGAAGATGCCCAAGATTTTGTCGATAAAC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTTTGATCGCGTACGAATCAAGGATATTATGGGC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACAAAACACAGGTGGGGGTGCAGGAAGCACAACAGA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TGTGACGCAATCATTCAGAAAATCAAATCTATAGAG
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AATACCTTAAATAATCCTTTGATTGATCCATCTAGTC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TAAAGAGAATAAGGACGATCCATCCAATCGGCTAAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTTTATGGCAACGGCTTTATCTTTTAAGGATAAA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AGTAACGGTGGTTTTGCCGTCTTCATCGGTAACAGT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CTAGACGTTACAGCGACATTCAACGAGCAGGGGAA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACCAATCCCCTCCCCAAGATATAGCAAAAATGGATC
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TTATTGTCTACCGTTACCTATGGAGATTGAGCTTAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GTAACGCTCCCCCAATTAATCCAGCCCCAACTGTAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CTTTAGCTGTTTTTGCAGGTCGTTTAACCGCTTTT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAAGCCAGCCCAGTCTATCGAAGCTTAATCATT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	CTGTTGACGACGACCAACGCCGTCCAAATTGT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	TAAAAATGATCTGTTGTTTCCCGTCCGGTCCACGA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	AAACGCAATTTTAAGCCCTTGGGGACTATTGTCTA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	ACTCAAGCCATTAGACCTGTGGGAATAATTGGGCAAA
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC	GGCGAAAATGAAGACGACGACGATGTGGTGACGGAAAT
GTTTCAATCCCATTGCTAGGATTCATTAATAAGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_015957287.1\|4322320_4323664_-\|TldD/PmbA-family-protein	unknown	unknown	gnl\|CDD\|223389
NC_011726.1\|WP_015785120.1\|4339953_4340637_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl\|CDD\|235140
NC_011726.1\|WP_015957291.1\|4331769_4333254_-\|transposase	c2c8_V-U2	-	gnl\|CDD\|223747
NC_011726.1\|WP_015785119.1\|4339668_4339950_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl\|CDD\|235659
NC_011726.1\|WP_015957289.1\|4325949_4327320_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224276
NC_011726.1\|WP_015785115.1\|4336080_4336449_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|180986
NC_011726.1\|WP_015785118.1\|4339160_4339559_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NC_011726.1\|WP_015957286.1\|4322025_4322235_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NC_011726.1\|WP_015785108.1\|4325162_4325921_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_015957294.1\|4338264_4339164_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NC_011726.1\|WP_015957288.1\|4323660_4325100_-\|TldD/PmbA-family-protein	unknown	unknown	gnl\|CDD\|223389
NC_011726.1\|WP_015957292.1\|4333439_4333985_-\|rod-shape-determining-protein-MreD	unknown	unknown	gnl\|CDD\|274574
NC_011726.1\|WP_015785116.1\|4336453_4337707_-\|RNA-polymerase-sigma-factor-SigC	unknown	unknown	gnl\|CDD\|236067
NC_011726.1\|WP_015785113.1\|4333981_4334731_-\|rod-shape-determining-protein-MreC	unknown	unknown	gnl\|CDD\|237560
NC_011726.1\|WP_015957285.1\|4320132_4321467_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|273206
NC_011726.1\|WP_015957283.1\|4317410_4318466_+\|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	unknown	unknown	gnl\|CDD\|340818
NC_011726.1\|WP_015785104.1\|4321537_4321756_-\|prevent-host-death-protein	unknown	unknown	gnl\|CDD\|171099
NC_011726.1\|WP_015957284.1\|4318501_4320103_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227621
NC_011726.1\|WP_015957290.1\|4327593_4328397_+\|carbonic-anhydrase	unknown	unknown	gnl\|CDD\|238449
NC_011726.1\|WP_015785114.1\|4334757_4335807_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237562

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_015785120.1\|4339953_4340637_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	2.22728e-152
NC_011726.1\|WP_015957291.1\|4331769_4333254_-\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.79253e-26
NC_011726.1\|WP_015785119.1\|4339668_4339950_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl\|CDD\|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	6.70403e-43
NC_011726.1\|WP_015957289.1\|4325949_4327320_-\|hypothetical-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	8.30059e-17
NC_011726.1\|WP_015785115.1\|4336080_4336449_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|180986	PRK07459, PRK07459, single-stranded DNA-binding protein; Provisional.	1.16245e-74
NC_011726.1\|WP_015785118.1\|4339160_4339559_-\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	5.2256e-32
NC_011726.1\|WP_015957287.1\|4322320_4323664_-\|TldD/PmbA-family-protein	gnl\|CDD\|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	9.46457e-38
NC_011726.1\|WP_015957290.1\|4327593_4328397_+\|carbonic-anhydrase	gnl\|CDD\|238449	cd00884, beta_CA_cladeB, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	6.59421e-96
NC_011726.1\|WP_015957294.1\|4338264_4339164_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	5.88029e-137
NC_011726.1\|WP_015957288.1\|4323660_4325100_-\|TldD/PmbA-family-protein	gnl\|CDD\|223389	COG0312, TldD, Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only].	2.92845e-91
NC_011726.1\|WP_015957286.1\|4322025_4322235_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	1.83085e-12
NC_011726.1\|WP_015785116.1\|4336453_4337707_-\|RNA-polymerase-sigma-factor-SigC	gnl\|CDD\|236067	PRK07598, PRK07598, RNA polymerase sigma factor SigC; Validated.	0
NC_011726.1\|WP_015785113.1\|4333981_4334731_-\|rod-shape-determining-protein-MreC	gnl\|CDD\|237560	PRK13922, PRK13922, rod shape-determining protein MreC; Provisional.	1.39077e-60
NC_011726.1\|WP_015957285.1\|4320132_4321467_-\|replicative-DNA-helicase	gnl\|CDD\|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_011726.1\|WP_015957283.1\|4317410_4318466_+\|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase	gnl\|CDD\|340818	cd03785, GT28_MurG, undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	3.76302e-130
NC_011726.1\|WP_015785104.1\|4321537_4321756_-\|prevent-host-death-protein	gnl\|CDD\|171099	PRK11409, PRK11409, YoeB-YefM toxin-antitoxin system antitoxin YefM.	4.38052e-07
NC_011726.1\|WP_015957284.1\|4318501_4320103_-\|hypothetical-protein	gnl\|CDD\|227621	COG5305, COG5305, Predicted membrane protein [Function unknown].	5.11907e-73
NC_011726.1\|WP_015957292.1\|4333439_4333985_-\|rod-shape-determining-protein-MreD	gnl\|CDD\|274574	TIGR03426, shape_MreD, rod shape-determining protein MreD. Members of this protein family are the MreD protein of bacterial cell shape determination. Most rod-shaped bacteria depend on MreB and RodA to achieve either a rod shape or some other non-spherical morphology such as coil or stalk formation. MreD is encoded in an operon with MreB, and often with RodA and PBP-2 as well. It is highly hydrophobic (therefore somewhat low-complexity) and highly divergent, and therefore sometimes tricky to discover by homology, but this model finds most examples. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	3.74431e-20
NC_011726.1\|WP_015785114.1\|4334757_4335807_-\|rod-shape-determining-protein	gnl\|CDD\|237562	PRK13927, PRK13927, rod shape-determining protein MreB; Provisional.	0

>NC_011726.1|WP_015957290.1|4327593_4328397_+|carbonic-anhydrase
MKKLIEGLQQFQTGYFSSHKALFEELSHGQHPRILFITCSDSRIDPNLITQAQVGELFVIRNAGNIIPPYRAANGGEGAAIEYAISALNIEEIIVCGHSHCGAMKGLLKLDSLSEKMPLVHDWLKHAEATRRVIKDNYGHFQGEELLEITVAENVLTQLENLQTYPVVRSRLHQGNLTLHGWIYRIETGEVLAYDGLSHDFVAPQSRLSVPEPEYNLHPSCPVSTQTPFTIPQSNGKGSDNANNGSSLPGYEHLSVEQSRRIYQGSR
>NC_011726.1|WP_015957289.1|4325949_4327320_-|hypothetical-protein
MKASQLLQQYEQGRRDFRGEDLRGQSFRGKNLAHTDFSQADIRGTNFTQANLTGAKFCQAKGGLTKPREILLGLISFLLAGLSGIFSGLSGGLVLLIFDSSHLINQIVGWTALIILMIFCIFSYYQGLTGGVAAATLSFMGTLVVALVITQEVSISVTTILYIGVIFIGHVAVALAGALTGALAGAFAGATVGAVIGVGAFPLAIIFALALAEANDKLFSIAGAVTAVIILSLLSIYLGLRAMKGDNRDSWLRHLAFAFSAIGGTSFYRANLTNADLTGALLKGTDLRDADLTRTRFYQAQQLNRARVDNTILAQPEIRDLLIDPTTGYKQYYYKANLRGANLDYANLHGANLKQADLTDATLRHANLEGANLTKILASGTDFSGATFHGVCIEGWKIDVFTKLGQVDCEYVFLREKPNEYGSRERCPYDPEGKFEPGDFELLYKVRNYAQAQLED
>NC_011726.1|WP_015785108.1|4325162_4325921_-|hypothetical-protein
MSEEALIVNRTGEPYQPARVYYQVSNKKTVLGVFKKLKCMDYEPMRDRWVWLYIAEAKKLRFEISYNKLPKNDPIVLGYFVFRSDQEMLLELRSFERVSAALNFFSPRINWRAAEPTRLRIVNKLFMTSQDNPPSPPNSFDEFFERDNVYINRPELLEQDIIEIQNQYDNEDEKSSAISDYMKQKARKPLPEIEEIPINVHNGGLLVLNMSLMMKHIETWERFQGNENFVMQDLIDKMLADIPDQELDLEED
>NC_011726.1|WP_015957288.1|4323660_4325100_-|TldD/PmbA-family-protein
MQINLQTILNSINLNADWIGLRQVTETTTTRSMRDGKPQSNGRSQTQGIMVEVLAQGQFGYSATNYLTIESIQKAAEVAYKQAINAANWAVHSFSIDQRPKAVGHYYSPYLKPLELLSPQDINDLLFKVCETLKVSDKIVKTSALAQITETEVQLISSNGSDIYQKFLFIVSNYAATAQDASIIQTRTDSGLGSRCYQGGTELLDLETSINRAKIIGEQAVELLSAPDCPTATTQLVLAPDQMMLQIHESIGHPLEIDRILGDERNYAGSSFVKLSDFGNLVYGSPLMNVTFDPSVSGQFASYGFDDGGLQATREYLIKDGILLRGLGSLESQTRAKIPGVANFRACSWNRAPIDRMANINLEPGTSHFNEMISEIEYGVYMESNRSWSIDDYRNKFQFGCEYAKLIENGQLTKTVKNPNYRGITNQFWRGLSQVGNESTVEMYGTPFCGKGEPNQAIRVGHSSPVCVFDNVEVFGGMA
>NC_011726.1|WP_015957287.1|4322320_4323664_-|TldD/PmbA-family-protein
MNLDRLEQLEVTFNQLSEFLIDQLNNAEHLSLELSSEQTQFIRFNNAKVRQTGLVTDGNIKLSFIANQRTVFMMFPFTGDLTTDQQNGLESLNYLRQDILQVPEDPHLVLPENKGTTREVYRGDLLVPEIAVKTLLPEVQNLDMTGIYTAGQVIRGNANSEGQNHWFATDSFCLDYSLIAPSEKAVKGILSGRNWDEQQYQTQIKSSQNQLLALNKSPKQIQPGGYRTYFAPAATADLLGMLSWGAISEASLRQGGSALMKLKEGKTLSPKLNLQENFSLGSVPKFNELGEISPDILPLITEGNLINTLVNSRTATEYKITANGANSSESLRSPELGKGTLSSEDIFNTLGTGLYLSNLHYLNWSDRTGGRITGMTRYACFWVENGEIVAPIKDLRFDDSLYRFWGENLEALTDFQEFIPETNTYERREIGGSLVPGMLVNDFQFTL
>NC_011726.1|WP_015957286.1|4322025_4322235_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MKLPYSIVIQWSNEDQKYIVSLPEFGPYAHTHGETYEESIKNAQEVLELLIEDYQARGKPLPIPLISSA
>NC_011726.1|WP_015785104.1|4321537_4321756_-|prevent-host-death-protein
MFSYEITSPTEAKNSFFELLYKLAKNHQVFLINRQERENVALIAESNLVNLVETVYLLRSPANASRLFAALE
>NC_011726.1|WP_015957285.1|4320132_4321467_-|replicative-DNA-helicase
MVADYTLPPQNIEAEESILGGILLDREAMGRVADLITPDAFYVQAHKDIYEAALKLYAQGKPTDFLTVKSILEDHQLLEKVGGTDKLNQLLDSTVAAVNIDRYAALVMDKYLRRQLISAGHEITELGFETTKELEQVLDESEKKIFSLTQKRPQEGLIPIADTLVQTYSELEKRHQKTALPGIQTDFYDLDAMTGGLQRSDLIIIAGRPSMGKTAFGLAMAANVAQKSQLPVAIFSLEMSKEQLSLRLLAAESKIEGNRLRTGRFVQNEYEQLSMAIGTLSEMPIYIDDSATTSVMQIRSQVRRLQAEKKGELGLVLIDYLQLMEGSGGDNRNQELSKITRSLKGLAREAQVPVIALSQLSRGVEARNNKRPMMSDLRESGAIEQDADLIMMLYRDEYYNPDSVDRGIAEVIITKHRNGPTGVVKLLFQPEFTQFLNMQTKSNY
>NC_011726.1|WP_015957284.1|4318501_4320103_-|hypothetical-protein
MNLSNLIKPKQFQDYFYLVILIIIILGIFFRFYNLDKKVYWHDEVYTSLHLTGYTLPEWQDPLFTGNIIGVDDLQYYLQSNPNKTLNDTLKVLAVDDPHHPPLYYILARYWRQFWGDSINIIRSFSAVCSLLVFPAIYWLAWELFGTSLVGIMSLGLIAISPFFILYAQEAREYSLWTVFVILSNSSLLRAIKLTQKNPNLQNNFYPFWGLYALLTTFSLYTSLVTIFVIIAQTTYTLLTEGLRFTKSVILQGLSVLASLIAFLPWILVFIDNYEQYKLITSWTKEIKLPFFELFKNWGLNLSRIFFDINWNLDNLLIYLVVFLSLVLVIYSLYFLCQNTTKQAWGLIFALIVTPFIFLFIPDLLWGGVRSLSPRYLIPSIIAIYLAVAYLLVNQLTQKNSNKIRIWSIITAIIFSSGVISSAISSQADTWWTKVISSGFPQVSRIINSSDNPLLISNDKSYHPGNIMSLSYLLKSEVKLQLLSEEKGYKIPNNFSNIFLLSPSDEFRKNLENQSSVKLKKVFSDSHLQLWKI
>NC_011726.1|WP_015957283.1|4317410_4318466_+|undecaprenyldiphospho-muramoylpentapeptide-beta-N-acetylglucosaminyltransferase
MARLLIAASGTGGHLFPALALAEHLPDYQIEWLGVPDRLEQTLVGDRYPLHSIAVEGFQTRSVLKNLQILFKLIRGIFEVRHLIKTHHIDVVFTTGGYIAAPAILGARLAGIRAILHESNFIPGKVTRLLSRFCDRVALGFAGTAQYLPKAKTVWVSTPVRSPFYTPQPLDLPIPENVPLIAVIGGSQGAIAVNQLVRQCVPSWLAAGAYIVHLTGKNDPEAETFKHPHYFALPFYDNMAGLLQRANLAVSRAGAGTLTELAITGTPSILIPYPFAAEDHQAYNAQVFADAQAALLYRQAELTPEILENAVLNCLKHPETLESMAKQAQRLAVLDSAQQLATLVNGFVQVT
>NC_011726.1|WP_015957291.1|4331769_4333254_-|transposase
MFAIKSMSELVQHHITIQLKAYLSTTQTALFENWTDSLRPLYNLALGLLYEEQQRRWRTNQKFLKNYLDKSSLQTYLNEIENKPDIYPVEWHITKALPECDWLTKEENEVRKKDNTKSLACRTINRDGNFFTPIRPYWHLEEPQKLAKFKCFTNQWLISCNLLTNYHLQKLLNVNMKVRQSFISMNLMEAWKRYQKGDFRKLKFKSKRNPVISLCNKQTNRIKFDPEANNCQLLGKEFGLIEFRGLHNRHQGQIQPRNGSLTKKADGYYLNLVFQVEHKPIPDSDLQVGIDPGLVTLLTLSDGKCISNQRFLKENERHLTVLQKKLSRQTPGSKNWEKTKKALAKIHKQTADHRKYYNHKVSTHLVNKYGAIAIEDTKLTNMNKRPKAEKREDGKGYEHNGAKAKAGLNQSFHDAGLGQLRAFLESKANSYENRHIERVRANYTSQKCSRCGHTDSENRLTQASFHCLKCGLEMPADLNAAINIEQTAFGLDKS
>NC_011726.1|WP_015957292.1|4333439_4333985_-|rod-shape-determining-protein-MreD
MKVWFHYSVVNRLVIAGSVILCLLLSPTRLPGMELLGVGTNWVLIWVVVWSLKRSVFQGITAGLVLGLIQDGLTGAYPSHVFSLVVVGFLTAKLQKQRYIQEDFISVALITFAMVIVAESITAGQYILANIRPLEEIWLDYQRFVLSSAILSSLWAPVLYYPLNSWWQKAPVTSPYKVKKR
>NC_011726.1|WP_015785113.1|4333981_4334731_-|rod-shape-determining-protein-MreC
MLIIRRWYVNYGSKLVWAVVALAIGWFLRQTQGAPLLELYYWVSRPFHSAPPSLLEERLTNARIVELEQRLAELERQNQQLQRLLGYYQQQQAGVITAPIIGRSTDDWWKQVIIGRGSQDGIKVGYVVTGIGGLIGRVIDVTPNTSRVLLVSDPTSRVGATVSRSRTMGVVEGESAQIAVMRFFEKVPQVRPGDTITTSPVSRLFPGGLPIGQVESVNLEKSPAPEAKIRLTAPINDLEWAIVHPFESQ
>NC_011726.1|WP_015785114.1|4334757_4335807_-|rod-shape-determining-protein
MPRNFWNRFSLSRDMGIDLGTANTLVYVSGKGIVLEEPSVVAIDQDRKIPLAVGEEAKKMLGRTPGNVIALRPLRDGVIADFLSAMIMLKEFIQRAHEGSPLGNPRMVIGIPSGITEVERRAVIDAAREAGARDVGLIEEPIAAALGAGLPVTEATGNMIVDIGGGTTEVAVLSLQGRVLSESVRVAGDELTESIIGYMKKVHNLVIGERTAEEIKIRLASAYPLRHEEEPIMDVRGLHLMSGLPRTVTVKGEEVRESMAEPLAVIVDAVKRTLERTPPELAADIIDRGIMLAGGGALLRGLDTLLSHETGIVTHIAEDPLRCVVKGTGEVLKNPKILDRVLSESSRLV
>NC_011726.1|WP_015785115.1|4336080_4336449_+|single-stranded-DNA-binding-protein
MSLNVVHLVGRAGRDPEVKYFESGKVLCELTLAVNRRTSKSDEPDWFNLKIWGKTAEIAANYVRKGGLIGIQGSLTIETWTDRNTGANRSKPVILVDRLDLLGSKRDEEGGLGSNYPMTDEF
>NC_011726.1|WP_015785116.1|4336453_4337707_-|RNA-polymerase-sigma-factor-SigC
MPATPFYSDTDYYSPLASDGNASSVGFSEKAYELREGSLELELHGIDFTEAEKNHHQGSTDLVRLYLQDIGRVPLLNQEEEVIKAQQVQSYVELLDLRQKAAQAGDRAIQQLIEMAEIHDRLFISLGYRPSWDRWAKAAQISVGELKTILGQGKERWAQLADIELDQLETIEKVGIRAKEQMIKANLRLVVSVAKKYQHRGLELLDLIQEGTLGLERAVEKFDPTKGYRFSTYAYWWIRQGITRAISTQSRIIRLPVHITEKLNKIKRAQRKLSQEKGRKATIEEMSKELDMSAEQIREVLLRIPRSVSLEVKVGKEKDTELVDLLETECQSPEESLISESLRKDLQVLLEDLTEREQDVIKLRYGFEDGTCYSLADIGRVLELSRERVRQIEAKALQKLRQPRRRNQIRDYFESLT
>NC_011726.1|WP_015957294.1|4338264_4339164_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MNTPLIVICGATATGKSGLALTLAQRLDSIIISADSRQVYREFDIGTAKPTHAEQDLVPHYLIDICSPTQTFTVADYQDKVTKLLQSTPCLSPSLLVGGTGLYIKSIVRGLKIPRVAPQPQLRQELEALGQAQCYAMLNQVDSLGAHKIHPHDQVRTLRALEVFYVTGVPISQQQGEYPPTYPILQIGLDSTPDALEKRIEQRTQMMLTMGLVKEVETLMEKYGSDLPLLNTLGYAEIKEYLQGKMSLDQAKAAIILHTRQFAKRQRTWFRSYREIQWFDPTSVNFLDNVWMTIQQFLA
>NC_011726.1|WP_015785118.1|4339160_4339559_-|transcriptional-repressor
MKGQRTRSQERIVRLLKSLNHAVSAQDLYLELKTRDQALGLATVYRSLEALKLEGTVQARTLTNGEAVYSLVAKDQHHLTCVNCGQSFPIDECPVHDLEQRLEKSHRFQVYYHTLEFFGLCYDCQLSAERNR
>NC_011726.1|WP_015785119.1|4339668_4339950_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MSQQYQCRIYVTLRPSVLDPAGTAVESGLKQLGYEGVERVRIGKYIELNLTAKDEIEAEKQLHEMCDRLLANPVIENYCFEMTPVHATQVCGG
>NC_011726.1|WP_015785120.1|4339953_4340637_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKFGIVVFPGSNCDRDLQTVTQGLLNQPTRMIWHQETDLNDLDVILIPGGFSYGDYLRCGAIARFSPIMPHVIEHANQGKLVLGICNGFQILTEIGLLPGALIRNRDLHFICDRVSLRVEHNQSPWTQTYTSEQVITLPIAHGEGRYYADGDTLKQLEDNGQILLRYCTPTGEIEETANPNGSLYNIAGISNKQGNVFGLMPHPERASDPLVGAMDGRGLFEGLIAA

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Crispr_ID: NC_011726_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_11

4342782-4342890

TypeV

Consensus_repeat	Method
TTTTATTAAGAGAAATTAGTTGAATGGAAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011726_11

>merge|NC_011726|11|4342782-4342890|CRISPRCasFinder
TTTTATTAAGAGAAATTAGTTGAATGGAAACAGCAGAAAATACTAAAGTAGGCAGTAAATCAGACTCTAATTTCTCTCTTTTATTAAGAGAAATTAGTTGAATGGAAAC

>NC_011726|11|10|4342782-4342890|CRISPRCasFinder
TTTTATTAAGAGAAATTAGTTGAATGGAAAC	AGCAGAAAATACTAAAGTAGGCAGTAAATCAGACTCTAATTTCTCTC
TTTTATTAAGAGAAATTAGTTGAATGGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_015785128.1\|4346497_4346617_-\|photosystem-II-reaction-center-protein-J	unknown	unknown	gnl\|CDD\|179446
NC_011726.1\|WP_015957296.1\|4344525_4345524_+\|UDP-glucose-4-epimerase-GalE	unknown	unknown	gnl\|CDD\|224012
NC_011726.1\|WP_015785120.1\|4339953_4340637_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl\|CDD\|235140
NC_011726.1\|WP_015785114.1\|4334757_4335807_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237562
NC_011726.1\|WP_015785126.1\|4345648_4345924_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224380
NC_011726.1\|WP_015785127.1\|4345932_4346349_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_015785115.1\|4336080_4336449_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|180986
NC_011726.1\|WP_015785123.1\|4342201_4342492_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
NC_011726.1\|WP_015785131.1\|4347281_4348292_-\|photosynthesis-system-II-assembly-factor-Ycf48	unknown	unknown	gnl\|CDD\|237468
NC_011726.1\|WP_015785118.1\|4339160_4339559_-\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|223806
NC_011726.1\|WP_015785121.1\|4340644_4341598_-\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|237771
NC_011726.1\|WP_015785124.1\|4342897_4344388_-\|polyphosphate:AMP-phosphotransferase	unknown	unknown	gnl\|CDD\|274736
NC_011726.1\|WP_015785129.1\|4346781_4346916_-\|cytochrome-b559-subunit-beta	unknown	unknown	gnl\|CDD\|235051
NC_011726.1\|WP_015957294.1\|4338264_4339164_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NC_011726.1\|WP_015785132.1\|4348381_4348729_-\|rubredoxin	unknown	unknown	gnl\|CDD\|366011
NC_011726.1\|WP_015785116.1\|4336453_4337707_-\|RNA-polymerase-sigma-factor-SigC	unknown	unknown	gnl\|CDD\|236067
NC_011726.1\|WP_015785119.1\|4339668_4339950_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl\|CDD\|235659
NC_011726.1\|WP_015957295.1\|4341624_4342218_-\|TolB-family-protein	unknown	unknown	gnl\|CDD\|223893
NC_011726.1\|WP_012598216.1\|4346652_4346772_-\|photosystem-II-reaction-center-protein-L	unknown	unknown	gnl\|CDD\|134373
NC_011726.1\|WP_015785130.1\|4346942_4347188_-\|cytochrome-b559-subunit-alpha	unknown	unknown	gnl\|CDD\|179444

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_015785128.1\|4346497_4346617_-\|photosystem-II-reaction-center-protein-J	gnl\|CDD\|179446	PRK02565, PRK02565, photosystem II reaction center protein J; Provisional.	2.57834e-11
NC_011726.1\|WP_015957296.1\|4344525_4345524_+\|UDP-glucose-4-epimerase-GalE	gnl\|CDD\|224012	COG1087, GalE, UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane].	0
NC_011726.1\|WP_015785120.1\|4339953_4340637_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	2.22728e-152
NC_011726.1\|WP_015785114.1\|4334757_4335807_-\|rod-shape-determining-protein	gnl\|CDD\|237562	PRK13927, PRK13927, rod shape-determining protein MreB; Provisional.	0
NC_011726.1\|WP_015785126.1\|4345648_4345924_+\|hypothetical-protein	gnl\|CDD\|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	0.0038395
NC_011726.1\|WP_015785115.1\|4336080_4336449_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|180986	PRK07459, PRK07459, single-stranded DNA-binding protein; Provisional.	1.16245e-74
NC_011726.1\|WP_015785123.1\|4342201_4342492_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	1.8489e-21
NC_011726.1\|WP_015785131.1\|4347281_4348292_-\|photosynthesis-system-II-assembly-factor-Ycf48	gnl\|CDD\|237468	PRK13684, PRK13684, photosynthesis system II assembly factor Ycf48.	0
NC_011726.1\|WP_015785118.1\|4339160_4339559_-\|transcriptional-repressor	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	5.2256e-32
NC_011726.1\|WP_015785121.1\|4340644_4341598_-\|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase	gnl\|CDD\|237771	PRK14619, PRK14619, NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Provisional.	0
NC_011726.1\|WP_015785124.1\|4342897_4344388_-\|polyphosphate:AMP-phosphotransferase	gnl\|CDD\|274736	TIGR03708, poly_P_AMP_trns, polyphosphate:AMP phosphotransferase. Members of this protein family contain a domain duplication. The characterized member from Acinetobacter johnsonii is polyphosphate:AMP phosphotransferase (PAP), which can transfer the terminal phosphate from poly(P) to AMP, yielding ADP. In the opposite direction, this enzyme can synthesize poly(P). Each domain of this protein family is homologous to polyphosphate kinase, an enzyme that can run in the forward direction to extend a polyphosphate chain with a new terminal phosphate from ATP, or in reverse to make ATP (or GTP) from ADP (or GDP). [Central intermediary metabolism, Phosphorus compounds].	0
NC_011726.1\|WP_015785129.1\|4346781_4346916_-\|cytochrome-b559-subunit-beta	gnl\|CDD\|235051	PRK02561, psbF, cytochrome b559 subunit beta; Provisional.	4.5289e-23
NC_011726.1\|WP_015957294.1\|4338264_4339164_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	5.88029e-137
NC_011726.1\|WP_015785132.1\|4348381_4348729_-\|rubredoxin	gnl\|CDD\|366011	pfam00301, Rubredoxin, Rubredoxin.	1.30104e-22
NC_011726.1\|WP_015785116.1\|4336453_4337707_-\|RNA-polymerase-sigma-factor-SigC	gnl\|CDD\|236067	PRK07598, PRK07598, RNA polymerase sigma factor SigC; Validated.	0
NC_011726.1\|WP_015785119.1\|4339668_4339950_+\|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl\|CDD\|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	6.70403e-43
NC_011726.1\|WP_015957295.1\|4341624_4342218_-\|TolB-family-protein	gnl\|CDD\|223893	COG0823, TolB, Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion].	9.29901e-28
NC_011726.1\|WP_012598216.1\|4346652_4346772_-\|photosystem-II-reaction-center-protein-L	gnl\|CDD\|134373	PRK00753, psbL, photosystem II reaction center L; Provisional.	6.03477e-16
NC_011726.1\|WP_015785130.1\|4346942_4347188_-\|cytochrome-b559-subunit-alpha	gnl\|CDD\|179444	PRK02557, psbE, cytochrome b559 subunit alpha; Provisional.	5.32379e-57

>NC_011726.1|WP_015785123.1|4342201_4342492_-|helix-turn-helix-transcriptional-regulator
MVSSKLYSPASLSGREIEILDLVATGLTNLEIAEELEISKRTVDNHISNILTKTKTENRVELVRWALQWGKICLNDVNCCYLPSSTASQSINEAAS
>NC_011726.1|WP_015957295.1|4341624_4342218_-|TolB-family-protein
MKPRRKRFHQSLTLLLLLSSLTLGLGSCQPGTFITPPTLELGSALNSRSAEEFPRFSYDGRYLVFASDRQGQRGIWLYDRLNNRLLPLPGINQPGTRQDQPDISSDGRYIVYVSEQEGKPDIFLYDRFTFQREQITKNWLGEVRHPTISGNGRLIAFEANRQGQWDLVIYDRGLNTPLSVPNPQQKETGINTNPKNQ
>NC_011726.1|WP_015785121.1|4340644_4341598_-|NAD(P)H-dependent-glycerol-3-phosphate-dehydrogenase
MTHQLTNITIIGAGLWGLALAKLGNYNQHNQVTIWSRHSPDSLASIIGNTDVIVSAVSMPGVRPTIELLQSLNFPQNSIIVTATKGLDPITTDTPSQMWQAAFPEHSIVVLSGPNLSKEIDQGLPAATVVSSHNLAAAETIQERFSSEVFRVYVNSDPIGTELGGTLKNVMAIAAGVCDGLQLGTNAKAALVTRALPEMIRVGTYFGASPATFFGLSGLGDLMATCDSPLSRNYRVGYGLAQGKTLEEILLELKSTAEGINTTHVLVDLANKQGIVIPIAWEVERLLKGETTPQEAVQALIKRELKEEFGDLGFDRL
>NC_011726.1|WP_015785120.1|4339953_4340637_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKFGIVVFPGSNCDRDLQTVTQGLLNQPTRMIWHQETDLNDLDVILIPGGFSYGDYLRCGAIARFSPIMPHVIEHANQGKLVLGICNGFQILTEIGLLPGALIRNRDLHFICDRVSLRVEHNQSPWTQTYTSEQVITLPIAHGEGRYYADGDTLKQLEDNGQILLRYCTPTGEIEETANPNGSLYNIAGISNKQGNVFGLMPHPERASDPLVGAMDGRGLFEGLIAA
>NC_011726.1|WP_015785119.1|4339668_4339950_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MSQQYQCRIYVTLRPSVLDPAGTAVESGLKQLGYEGVERVRIGKYIELNLTAKDEIEAEKQLHEMCDRLLANPVIENYCFEMTPVHATQVCGG
>NC_011726.1|WP_015785118.1|4339160_4339559_-|transcriptional-repressor
MKGQRTRSQERIVRLLKSLNHAVSAQDLYLELKTRDQALGLATVYRSLEALKLEGTVQARTLTNGEAVYSLVAKDQHHLTCVNCGQSFPIDECPVHDLEQRLEKSHRFQVYYHTLEFFGLCYDCQLSAERNR
>NC_011726.1|WP_015957294.1|4338264_4339164_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MNTPLIVICGATATGKSGLALTLAQRLDSIIISADSRQVYREFDIGTAKPTHAEQDLVPHYLIDICSPTQTFTVADYQDKVTKLLQSTPCLSPSLLVGGTGLYIKSIVRGLKIPRVAPQPQLRQELEALGQAQCYAMLNQVDSLGAHKIHPHDQVRTLRALEVFYVTGVPISQQQGEYPPTYPILQIGLDSTPDALEKRIEQRTQMMLTMGLVKEVETLMEKYGSDLPLLNTLGYAEIKEYLQGKMSLDQAKAAIILHTRQFAKRQRTWFRSYREIQWFDPTSVNFLDNVWMTIQQFLA
>NC_011726.1|WP_015785116.1|4336453_4337707_-|RNA-polymerase-sigma-factor-SigC
MPATPFYSDTDYYSPLASDGNASSVGFSEKAYELREGSLELELHGIDFTEAEKNHHQGSTDLVRLYLQDIGRVPLLNQEEEVIKAQQVQSYVELLDLRQKAAQAGDRAIQQLIEMAEIHDRLFISLGYRPSWDRWAKAAQISVGELKTILGQGKERWAQLADIELDQLETIEKVGIRAKEQMIKANLRLVVSVAKKYQHRGLELLDLIQEGTLGLERAVEKFDPTKGYRFSTYAYWWIRQGITRAISTQSRIIRLPVHITEKLNKIKRAQRKLSQEKGRKATIEEMSKELDMSAEQIREVLLRIPRSVSLEVKVGKEKDTELVDLLETECQSPEESLISESLRKDLQVLLEDLTEREQDVIKLRYGFEDGTCYSLADIGRVLELSRERVRQIEAKALQKLRQPRRRNQIRDYFESLT
>NC_011726.1|WP_015785115.1|4336080_4336449_+|single-stranded-DNA-binding-protein
MSLNVVHLVGRAGRDPEVKYFESGKVLCELTLAVNRRTSKSDEPDWFNLKIWGKTAEIAANYVRKGGLIGIQGSLTIETWTDRNTGANRSKPVILVDRLDLLGSKRDEEGGLGSNYPMTDEF
>NC_011726.1|WP_015785114.1|4334757_4335807_-|rod-shape-determining-protein
MPRNFWNRFSLSRDMGIDLGTANTLVYVSGKGIVLEEPSVVAIDQDRKIPLAVGEEAKKMLGRTPGNVIALRPLRDGVIADFLSAMIMLKEFIQRAHEGSPLGNPRMVIGIPSGITEVERRAVIDAAREAGARDVGLIEEPIAAALGAGLPVTEATGNMIVDIGGGTTEVAVLSLQGRVLSESVRVAGDELTESIIGYMKKVHNLVIGERTAEEIKIRLASAYPLRHEEEPIMDVRGLHLMSGLPRTVTVKGEEVRESMAEPLAVIVDAVKRTLERTPPELAADIIDRGIMLAGGGALLRGLDTLLSHETGIVTHIAEDPLRCVVKGTGEVLKNPKILDRVLSESSRLV
>NC_011726.1|WP_015785124.1|4342897_4344388_-|polyphosphate:AMP-phosphotransferase
MLDNLDLKLTLDKETYQSQLEQLMRQLRSLQKACWDNKLPVIIVLEGWAAAGKGTLLQKTIGYMDPRGFTVHPILAATPDEEKYPFLWRFWHKLPAKGSIGIFYHSWYTHVLEDRLFQKVNNSDIPLLMRDINAFEHQLVDDGVAMAKFWIHLSRKEMKKRLKKYEADELESWRVRPEDWQQANRYDEYAALAEEMLTFTSTGHAPWTLVEGDCQRWTRIKVLSQIVATITQALDLRKLPQTAIPSLPPQTELQPTEPDFLGKVDLSLHLSKDEYRQRLGEAQVKLRQLQLRIFRENIPVLVTFEGWDAAGKGGAIKRLTDTLDPRSYKVNAFAAPSQEEKQYHYLWRFWRYLPGGGTIGIFDRSWYGRVLVERIEGFANELEWRRSYKEINEFEAQLTHGGYVLVKFWLHIGLDEQLRRFEERRDNPFKNYKLTDEDWRNRDKFPLYYVAVNQMIARTSTPAAPWYIVPGNDKYYARVFVIETLISAIETELKRR
>NC_011726.1|WP_015957296.1|4344525_4345524_+|UDP-glucose-4-epimerase-GalE
MSKKTTILVTGGAGYIGSHAVLALQKSGYDVIILDNLSYGHRELVKEVLKVELIVGDTNDRPLLDQLFANREITAVMHFAAYIAVGESVVNPSIYYRNNVVGTLTLLEAMLAAKINKFVFSSTCAIYGMPQEIPMTENHPQDPLSPYAASKFMVEQILEDFDHAYGFKSVAFRYFNASGADPQGNLGEDHHPETHLIPLALLTALKKRDSLSIFGTDYKTPDGTAVRDYIHVNDLASAHVLGLEYLLNGGKSEVFNLGNGNGFSVREVIETAKKITGIDFLVKESDRRPGDAPILVGSSEKARNILGWQPQYADLETIIDHAWSWHQKRHGS
>NC_011726.1|WP_015785126.1|4345648_4345924_+|hypothetical-protein
MSDNTKQLESIIERIGEAVLATTDTVESIAHRLHQISDKIEQQDHQIQQQGYQIFALTESIQTLVDSQAESREQLTQLTKLLEILVTKINS
>NC_011726.1|WP_015785127.1|4345932_4346349_+|hypothetical-protein
MIKIFTLIFLLTFTLFGCAETKVSQCQKIILITKNIAQESENNRQTKDIQKALKVADAFEEAAQNMKDLKISDEQLVKYQLGFAEVYQGYAQTTRQFVAALQKKDIPTLQLMQQQLRQLGRKEPELGEAMNRYCQSNL
>NC_011726.1|WP_015785128.1|4346497_4346617_-|photosystem-II-reaction-center-protein-J
MFAEGRIPLWIVGVIAGMGVIAVVGLFFYGAYAGLGSSM
>NC_011726.1|WP_012598216.1|4346652_4346772_-|photosystem-II-reaction-center-protein-L
MERNTNPNRQPVELNRTSLYLGLLLVAVLGILFSSYFFN
>NC_011726.1|WP_015785129.1|4346781_4346916_-|cytochrome-b559-subunit-beta
MTSNNPNQPVSYPIFTVRWLSVHALAVPTVFFIGAISAMQFIQR
>NC_011726.1|WP_015785130.1|4346942_4347188_-|cytochrome-b559-subunit-alpha
MSGSTGERPFSDIVTSIRYWVIHSITIPMLFIAGWLFVSTGLAYDVFGTPRPDQYFTQERQELPIISDRYKASQQIQEFNK
>NC_011726.1|WP_015785131.1|4347281_4348292_-|photosynthesis-system-II-assembly-factor-Ycf48
MSMNAFMRNLKQIVILLAISLFCISCSNVPSTSYNPWKTITLETESTFADVAFTGDLNHGWLVGSQAALFETTDGGNTWEERKLDLSDEKVSFTGVSFHENEGWVTGKPAILLHTDDGGQNWSRIPLSEKLPGAPYGIIALGSQTAEMVTDLGAIYKTTNGGKTWQALVEGSVGVARNITRSSDGRYVAVSARGNFYSTWEPGQREWTPHNRNSSRRLQKMGYSDKGGLWLLARGGQLQFSSADDLEDWQEEIYPEFSTSWGLLDLAYRTPDELWVAGGSGNLLFSPDQGETWEKDRAIESVPSNLYKIVFITPEQGFVLGQNGVLLKYEPSTEPA
>NC_011726.1|WP_015785132.1|4348381_4348729_-|rubredoxin
MSERPTEKTLAEQAPANHECRLCGYVYEPKKGDAKGNIDPGTPFEDLPITWRCPVCGARSNQFSNVGATNAPSGFQENLNYGFGVNNLTPGQKNLLIFGGLALGFLFFLSLYGLN

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Crispr_ID: NC_011726_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_12

4398255-4398335

TypeV-U4

Consensus_repeat	Method
TTGCTGTTTATTGGCTTCTTGAAAGGC	CRISPRCasFinder

1 spacers

c2c9_V-U4

The CRISPR arrays of NC_011726_12

>merge|NC_011726|12|4398255-4398335|CRISPRCasFinder
TTGCTGTTTATTGGCTTCTTGAAAGGCTTGTATTTGTTGCCGATTAGCCTCTATTTGCTGTTTATTGGCTTCTTGAAAGGC

>NC_011726|12|11|4398255-4398335|CRISPRCasFinder
TTGCTGTTTATTGGCTTCTTGAAAGGC	TTGTATTTGTTGCCGATTAGCCTCTAT
TTGCTGTTTATTGGCTTCTTGAAAGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_015785175.1\|4401685_4402951_+\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_011726.1\|WP_015785163.1\|4388774_4390520_-\|iron-uptake-porin	unknown	unknown	gnl\|CDD\|335962
NC_011726.1\|WP_015785178.1\|4406265_4408059_-\|translational-GTPase-TypA	unknown	unknown	gnl\|CDD\|224138
NC_011726.1\|WP_015785164.1\|4390863_4391796_-\|DUF1460-domain-containing-protein	unknown	unknown	gnl\|CDD\|369314
NC_011726.1\|WP_015957312.1\|4403240_4404551_-\|phytase	unknown	unknown	gnl\|CDD\|226698
NC_011726.1\|WP_015957313.1\|4404943_4406155_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	gnl\|CDD\|223747
NC_011726.1\|WP_015785165.1\|4391924_4392473_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|238182
NC_011726.1\|WP_015785168.1\|4394662_4394872_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_015785173.1\|4398911_4400186_+\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_011726.1\|WP_015785174.1\|4400182_4401007_-\|DUF3782-domain-containing-protein	unknown	unknown	gnl\|CDD\|372238
NC_011726.1\|WP_015785170.1\|4395910_4396852_-\|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223461
NC_011726.1\|WP_015785176.1\|4402901_4403087_-\|DUF4926-domain-containing-protein	unknown	unknown	gnl\|CDD\|379816
NC_011726.1\|WP_015785181.1\|4410955_4413385_+\|dynamin-like-GTPase-family-protein	unknown	unknown	gnl\|CDD\|223771
NC_011726.1\|WP_015957310.1\|4392575_4392842_+\|MoaD/ThiS-family-protein	unknown	unknown	gnl\|CDD\|340452
NC_011726.1\|WP_015785180.1\|4410430_4410856_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NC_011726.1\|WP_015957311.1\|4394928_4395756_-\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|223740
NC_011726.1\|WP_015785171.1\|4396880_4398134_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|274425
NC_011726.1\|WP_015785167.1\|4392899_4394426_-\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NC_011726.1\|WP_015785179.1\|4408480_4410430_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224720
NC_011726.1\|WP_015785162.1\|4387577_4388678_+\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|234565

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_015785175.1\|4401685_4402951_+\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.27969e-100
NC_011726.1\|WP_015957312.1\|4403240_4404551_-\|phytase	gnl\|CDD\|226698	COG4247, Phy, 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) [Lipid metabolism].	1.43933e-120
NC_011726.1\|WP_015785178.1\|4406265_4408059_-\|translational-GTPase-TypA	gnl\|CDD\|224138	COG1217, TypA, Predicted membrane GTPase involved in stress response [Signal transduction mechanisms].	0
NC_011726.1\|WP_015785164.1\|4390863_4391796_-\|DUF1460-domain-containing-protein	gnl\|CDD\|369314	pfam07313, DUF1460, Protein of unknown function (DUF1460). This family consists of several hypothetical bacterial proteins of around 260 residues in length. The function of this family is unknown.	1.70966e-63
NC_011726.1\|WP_015957313.1\|4404943_4406155_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.8478e-55
NC_011726.1\|WP_015785165.1\|4391924_4392473_-\|universal-stress-protein	gnl\|CDD\|238182	cd00293, USP_Like, Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, athough Usp lacks ATP-binding activity.	9.29379e-31
NC_011726.1\|WP_015785163.1\|4388774_4390520_-\|iron-uptake-porin	gnl\|CDD\|335962	pfam04966, OprB, Carbohydrate-selective porin, OprB family.	6.81079e-26
NC_011726.1\|WP_015785173.1\|4398911_4400186_+\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	4.80644e-110
NC_011726.1\|WP_015785174.1\|4400182_4401007_-\|DUF3782-domain-containing-protein	gnl\|CDD\|372238	pfam12644, DUF3782, Protein of unknown function (DUF3782). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 91 and 186 amino acids in length.	1.23936e-29
NC_011726.1\|WP_015785170.1\|4395910_4396852_-\|PhzF-family-phenazine-biosynthesis-protein	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	8.29459e-105
NC_011726.1\|WP_015785176.1\|4402901_4403087_-\|DUF4926-domain-containing-protein	gnl\|CDD\|379816	pfam16277, DUF4926, Domain of unknown function (DUF4926). This family consists of uncharacterized proteins around 70 residues in length and is mainly found in various Caulobacter, Microcystis and Cyanothece species. The function of this family is unknown.	1.19471e-07
NC_011726.1\|WP_015785181.1\|4410955_4413385_+\|dynamin-like-GTPase-family-protein	gnl\|CDD\|223771	COG0699, COG0699, Predicted GTPases (dynamin-related) [General function prediction only].	2.49847e-26
NC_011726.1\|WP_015957310.1\|4392575_4392842_+\|MoaD/ThiS-family-protein	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	4.40035e-25
NC_011726.1\|WP_015785180.1\|4410430_4410856_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.36075e-12
NC_011726.1\|WP_015957311.1\|4394928_4395756_-\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	9.90974e-42
NC_011726.1\|WP_015785171.1\|4396880_4398134_-\|glycosyltransferase	gnl\|CDD\|274425	TIGR03087, stp1, sugar transferase, PEP-CTERM/EpsH1 system associated. Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.	2.29309e-47
NC_011726.1\|WP_015785167.1\|4392899_4394426_-\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	2.97025e-50
NC_011726.1\|WP_015785179.1\|4408480_4410430_+\|hypothetical-protein	gnl\|CDD\|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	0.000144024
NC_011726.1\|WP_015785162.1\|4387577_4388678_+\|3-dehydroquinate-synthase	gnl\|CDD\|234565	PRK00002, aroB, 3-dehydroquinate synthase; Reviewed.	0

>NC_011726.1|WP_015785171.1|4396880_4398134_-|glycosyltransferase
MKILILSCAFPYPPLEGKTQMRTFSFLKYLNQRHDITFVTQASDEVLEEDIASLKQEIPNCIIFPDVTQETTSPRFLEKAKRLGVFFQQGTPPKLLSHYSLKLQEYLDQEIDSGQFDLLTCEGNNGEIYIRPEWQKKLPTVINIHRSLWGVYKHQRENHSGESGLRNQINLPLLRRYEKHYCSKFSAIVTATQTEQKLLKNLKLETPITVVPNGLDLSVFPKRPANSGGQRIIFIGAMDKPANIDAARFFSLEVFPKIRQRYPESILELVGIRPVHEVLELGEYPGIKVTGPVSSMIEYLHWATVCVIPLRKSMGTKIRTLQALATGTPLVASDYGLEGLSVDGTGVPLCAMRANEIDEYVYAIGRLFEQPKLREKLSINGRTLIENEYTWKRMGERYEQILLTTYNTSHKLSDNSP
>NC_011726.1|WP_015785170.1|4395910_4396852_-|PhzF-family-phenazine-biosynthesis-protein
MNLTQQYKFYTLDVFTDQIFGGNPLAVFPKAQGLTDEQMQKVAAEFNLSETVFVLPPETSKGTRKLRIFTPKVELPFAGHPTVGTAYLLSYLGEIDQPEEPDTDLSIIFEEGVGLVPVTIKIKQGKPVYTELQAAQLPEVKNDAPSIQELAEILGLEITDFREDQYSPQGVSCGVPFLLIPLQNRTALGRINFNRDRWQHILGKAWASAMYVFCDDPETEGTHLRSRMFAPAMGITEDPATGSAATAFGAYLALRHPLTEGTLQWRIEQGLEMGRPSILEVAVEKHQGEIREIRVGGSSVLVSEGTMTIPLVR
>NC_011726.1|WP_015957311.1|4394928_4395756_-|mechanosensitive-ion-channel-family-protein
MDAVPVQVNVVIETLKTQVTGFGLKLIGAILLWVIGQWLITKGVNLLAKVLKKQNIEPTLIAYVNNFLGIGLKIVLIVAILGYFGIETTSFAALLAAAGVAIGAAWGGLLANFAAGIFLVIFRPFSVGDFVCAGGVTGTVEEIGLFVTSINTIDNVRNIIGNNKIFADNIQNFTANPYRRVDLVAQLNHSVNYGEAINRLKATVSQIPNVIDHPSPEIEILEFNLAGPVLAVRPYCHNDHYWQVYFDTNKAIRETLGDAYPVPEQHYVIRQTSAI
>NC_011726.1|WP_015785168.1|4394662_4394872_+|hypothetical-protein
MNSHDLAKYIEAHEGITKPWLLIQLRLKKIQENRDKMSEQEYLTHIESLHQDLMKLGEWWVGIEDEVFQ
>NC_011726.1|WP_015785167.1|4392899_4394426_-|SagB/ThcOx-family-dehydrogenase
MSKSLTSIATHYHQRTKYHPETIARKSQGLDWSKQPSVFKQYKIGTSYDLTVYLSDKATSDEHTPYWRRLSRFLACSYGLTAKIPTMGEPLYLRAAPSAGGLYPAEVYLISRGTPQLPAGLYHYQPQTHSLIYFWESDVWSNLQEACAWDLDLEDAQLAIITTAIFYRSAWRYEDRAYRRILLDTGHLLGNIELAAAINHYRPHLIGGFSDYIINELLYLDPDQEAGITVISLKDLLNPQQNPSQSFKTTTLPSEIHTDYPSISDGELLYYFHQATEIRISERLPDATLSNEISNLEDKYNFPFCLKVSTKTKPINWGENLLNLEQTILKRRSTRAYTGANLTLEELNSLLNFTYQAQDYEDIGLDADPDYFDLSLIETFIAVSGVNGLEEGCYYYAPKAQELRQIRFKNFRQELHYLCLGQELGRDAAAVIFHTADLEKAVQKYGDRAYRYLHLDAGHLGQRLNLAAIELNLGVSGIGGFFDDQVNEVLGIPSDEAVLYITTLGRPH
>NC_011726.1|WP_015957310.1|4392575_4392842_+|MoaD/ThiS-family-protein
MDHHALNIQITIKLFAAYQDSYGVPELQREFPNQTTVKGVLDSLIHEHPELETWRDVTRFGVNFKFVEADTLLKDGDEVVLIPPVSGG
>NC_011726.1|WP_015785165.1|4391924_4392473_-|universal-stress-protein
MTNQVESRDTLTQPNPEPQVATVPYQKILVAVDYLADTPKVFEEALNLAKLNHSQLMIFYCIQGRIPGSIDLPIYAGMISYGGIYSQEMVELEEKVIEESTEELKAWLQRLTDEATQEGLKAAADYSYGEPGRQICSLAKNWGSDLIVVGRRGRSGLAELFLGSISNYVVHHSPCAVLVVQQ
>NC_011726.1|WP_015785164.1|4390863_4391796_-|DUF1460-domain-containing-protein
MKKILLPVLVPLFILISPQDVLPLQSQDQSLEYVQKRSQNSLAQVKQNSLEESKTKKEFKQIISHLKEQNFSDLSLGQTVQKVAEQFLGAAYIAGLLDKSEQEKLFISLKEFDCVLFVETVLGLSQNISRQETQYENFVKNIQDLRYANGIIDGYCSRLHYFSDWINDNQKRGNVKNITAELGGIKFDKTLTFMSKNRKLYPKLINNQANYQCILEREKQLNQLDLYYIPHNQIKAIYQKLQPGDIIAIATNIDGLDVTHTGLIYRTSEGNIAFIHASPAGQVTIAQDLQTYAQNVKNAVGIIVARPLTK
>NC_011726.1|WP_015785163.1|4388774_4390520_-|iron-uptake-porin
MSRLLNQLVKITPGLLGCLFLVAQSAIASPKTDFETANPETINPDEALGVLRNRPQMDNPMNRTSGQKFNTSASQVTSVSELRDVQPTEWAYEALRSLVERYGCIVGYPDRTFRGNRALSRWEFAAGLNACLNTIERLLQENVAVLREDIEKLKRLAQEFEAELAALGSRVSNLESRVSYLEDHQFSTTTQLKATSIFTWSNAWGERALDYREQDTYNQAIQNRRNTTAKRRLDDNSTLGYRVRLNFNTSFSGKDMLTARLQALTIVNYANPTGTSMARLGHDANNDSNVVIDNLWYRFPIGQFTGYVGGTGLDVDDIFDTGNPYGTSSDTGALSRFMRYDPLTMRGTEGIGAGFAYKFNDMFTVRGLYLTPGGEGNDPSQGRGLFNGSFTAGGQIGFKPTDGLTFNAQFLHKYFRPNGVNVTHGTGSGIASDPFLGAATITDNYGLNGNWRINETFNLTGWVGYALARGQGLDSRGRSRRGLGADIWSWMVGLNVIDLFKEGAVFSVGGGSITNARRVDALTGDLTVPDQDTPYIIEGQYRYPLNKNIDITPGLYVILEPDGNNQNNSIWVGVVRTTFKF
>NC_011726.1|WP_015785162.1|4387577_4388678_+|3-dehydroquinate-synthase
MSIIIPVKLPHTSYNIAIAPGSLSQLGSHLEPLKLGQKILIISNPEIFNYYGDVVVNSLKKSGFEVFTHLIPAGEAYKTLDSIAQVYDTALEHRLERSSTMIALGGGVIGDMTGFAAATWLRGINFVQVPTSLLAMVDASIGGKTGVNHPQGKNLIGAFYQPRLVFIDPSVLKTLPVREFRAGMAEVIKYGIIWDKALFEQLEQAKTLDHLNSLNDELLQTIITRSCQAKVDVVSQDEKESGLRAILNYGHTIGHAIESLTGYETINHGEAVAMGMVAAGKIAIKLSLWTQEETIRQDQLIDKVGLISTIPKTLDIDQVIESLQSDKKVKSGKVRFILPTSIGKVIISDQVSSEIIKSVMIHQVNK
>NC_011726.1|WP_015785173.1|4398911_4400186_+|insulinase-family-protein
MVQLIDRFKTVPYPANLIQLDHGLTLIHQYQPATPVAVVDVWVKAGTIVEPDNWSGMAHFLEHMIFKGSKRVLPGIFDQMIENSGGMANAATSYDYAHFFLTTAAEYLPDTLPYLAEILLHAEIPDEEFVRERDVVLEEIRSCYDDPDWLAFQSLCESLYQRHPYGRSILGHESQLLQHSPHQMRCFHRTHYQPDKMTVVVVGNLQEEVVLKLVNQEFGEFSAPSECPPIQTLAEPPLLEVRRTQMYLPRLEQARLLMGWIGPGVDCLEDGFGLDLISAILGVGRSSRLVQQLREQKHLVLDVESSFSLQRDSSLFTIAAWLDPQDLEIVEQLILDNLMELQVKPVTEEELERGKRLLCHDYIFSTETPGQLAGLYGYYQTIASAEVSLSYPRIIEQFSAKDLQRIADQYLSPERYAITVMQPC
>NC_011726.1|WP_015785174.1|4400182_4401007_-|DUF3782-domain-containing-protein
MTNSADIKALIREQLPSILAEDSSIRDFILRTVSDYYSPKQETDQKFEEFKERVDRILDQLERDREEQARKWDENTHKWDENTRKWDRILDQLERDREEQARKWDENNRRLDNFIHEQNQKWNQQYQQNQETLEEIKKMNRQYDSTIGALGSRWGLFSEASFRNALAGILKDSFGVEVVNINDYDPDGIVFGRPDQVEIDVIIKNGLVIVCEIKSSMSKSDIYTFGRKVEFYQQKYQRSVNRKIVISPMIAPNALPVAESLGIEVYSYADSVSI
>NC_011726.1|WP_015785175.1|4401685_4402951_+|insulinase-family-protein
MNRYQIQGIGEKQAVHRLRLDNGVVLIVGENPTADLIAGRIFLKNAGSLWESKEKAGLSNLLATVITKGTERLSSGEIAEAVESIGASLGANAASDYFMMGIKTVSSDFAFILALMGEILRSPTFPEAEVALEKHLIIQSIRSQQEQPFNVAFNQLRGLMYQEHPYGFSILGTEETVSQLCRDDLINYHNYHFRPDNLIISLSGRITLHDAISLVEKTLGDWEVPSHTLTPLSLPPLISSPVEKITFQETQQSIVMLGYLTGGVKSPEYPVLKLLSTYLGNGLSSRLFVELREKRGLAYDVSALYPTRLEPSQFVVYMGTAPDNTSIAIEGLQQECERLCYQELTPEELQGAKNKLLGQYALGKQTNSEIAQLYGWYETLGLGVEFDQEFQAMITEVTSQIAQSVAKNYLLSPYLSVVGPN
>NC_011726.1|WP_015785176.1|4402901_4403087_-|DUF4926-domain-containing-protein
MKLLESVTLLKKISKLNLYWGQVGTIVEEYQPQVFEVELSDTLFRINWVPQRKDREKVNNF
>NC_011726.1|WP_015957312.1|4403240_4404551_-|phytase
MNKIINSLAVACFSFAFSHQAAIAVQLATPTAETPPVIDEIVDPPGDADDPAIWLHPNDPSQSLVLGTLKNAGLGVYDLGGNLLQLIQPNSIRYNNVDLLYGFSLGGNSVDLAIASDRQNDILAIFKIDPMTRLLESIVSNNIGTIFTPVGQVSNGTTTAYGLATYTDLSTGKNYVFVSQRETGNVAQLELFDDGTGKVNYTQVRSLTLPIPPGGVLEDAQVEGMVADRELGYVYVGQENRGIWKFSASPNGSTLGQLIDAVKPEGTHLEADVEGLTIYYSDNGTGYLLASSQGDNTFAIYDRLGNNNYLGSFSIVASGGIDSVEESDGADVINVPLGSQFPFGLFVTQDGSNDPPELFFDPDDQEFVNVSSNFKFVPWETIANAFAPNPLLINTSSFDPRNPSSITVPEPTLSIWGLFVMLGVGYLKRGKNHPFR
>NC_011726.1|WP_015957313.1|4404943_4406155_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MKQRLKFRIYPTTSQKTALAKLFGCTRVVWNDALAHCQQEYREGRKKPNNTQLSSRLTQLKKTEEKIWLGEVSAIPLQQSLRDLEVAYSNFFKSCQGKRKGKKVKSPKFKSRKFRQSARFTDNGFKINQQNVYLAKIGKLKIVWSRELPSKPSSVTVIKDSANRYFLSFVCDVNSSPLAPNNNSIGIDLGIIDFATLNNGEKIKSPKPLKHNLKQLRRLQKNLSRKQKGSKRHEVARLKVAKLHAKITDIRTDFLHQLSTKLIRENQTIALEDLNASGMVKNRKLSRAISDLGWRSFRTMLETKGEIYGRDVRIINRWEATSQTCSSCGFKGGKKELNIREWTCLNCGAVHDRDVNAATNILKVAGGHPETKNGRGEKIRLSNKKAHLSEASTTPQYKQLSLF
>NC_011726.1|WP_015785178.1|4406265_4408059_-|translational-GTPase-TypA
MSLPIRNVAIIAHVDHGKTTLVDALLKQSGIFREGEDIPDCVMDSNTLERERGITILSKNTAVRYNDTLINIVDTPGHADFGGEVERVLGMVDGCILIVDANEGPMPQTRFVLKKALEKGLRPIVVVNKIDRPQADPNIAVDKVFDLFVELGADDDQCDFTTLFASGLSGYAKETLEEEGVDMKPLFEAILHHVPPPAGDVNKPLQLQVTTLDYSDYLGRIIIGRIHNGTIKAGQQAALMKEDGSIVRGKISKLLGFEGLQRVEMQEASAGYIVAVAGFADANIGETLTCPNEPQALPLIKVDEPTLQMTFSVNDSPFAGQEGKFVTSRQIRDRLHRELETNVALRVEDTDSPDKFAVSGRGELHLGILIETMRREGYEFQVSQPQVIYREVNGQPCEPYEYLVLDVPEEAVGASIERLGQRKGEMQDMQTGTNGRTQLEFVVPARGLIGFRGEFIRLSRGEGIMNHSFLEYRPFSGELATRYNGVITSFEEGVATFYALQNAEDRGVFFITPGTKVYKGMIIGESNRPQDVELNICKTKQLTNHRSATGDELVQLQAPEEMSLERALEYIGPDELVEVTPQSIRLRKMKAQKLVKR
>NC_011726.1|WP_015785179.1|4408480_4410430_+|hypothetical-protein
MAVILPLIALVLLLLIFYKKTNYFRHSLLSSSICWGLLLTIITEVLSLIQSLVFSYLSLGWGFINILLIFIYLNIKLTKHKKKIDLKKIFYKLSNFWIIIVLGVTFVVTIVGLTALISPPNNRDSMDYHMARVAYWIQNHSLNHYPTHYLAQLYQGPLAELIIVNLQILSGGDYLANLVQWLSLIGSLLGVSLIAKLLGADLWGQLFSAVVAATIPMGILQGSSTQNDYVASFWLVCLTYFVLLNVKGQRNWSNFLQLSFSLGLAILTKGTSYIYALPLIIWFLLSELKYLKWQIWKPTLMLGIVVFIINLGHYSRNYLLFGKIIFTGNKYTNDAFSLPIFISNFIRNIALHLRTPVQSFNFLLQKVVSLIHQILGIDISDIRTTWSGQEFQLYFPSGQEAVSSLLHENLAANTLHLLLIVGAIFILFFQGKYKKDKLLFYYCIILISMFFLFCLLLKWQPWNSRLHLPIFVLFSPFSGSVFSRFKSRSFITFLSIFLIISSFPWVFFNTSRPIISNLKTESILTTSRTNQYFNNWPTIKNPYLKATGYINSQECSKIGLTRDFQVWQYPLFIFIKPTTSNPLEIRNINVTNISSEKMKVEPYKHFIPCAIISLNFPDQKKKISKEINTNTGTYSIKFSSRLINVFMKQ
>NC_011726.1|WP_015785180.1|4410430_4410856_-|GNAT-family-N-acetyltransferase
MKDKVKIITQVNDSQIKDLYQLYQLSWWSQGRMLDGIKIMLENSDLIIGLSHCETEKLIGFARVLTDYVYRATIWDVMVDPSYQKKGLGSLLMESIMNHQSLRNVECFSLMCLPEAIPFYEKFEFATYHKPIEIMIRSRHS
>NC_011726.1|WP_015785181.1|4410955_4413385_+|dynamin-like-GTPase-family-protein
MTELVPQCQNLSTQVNSLLELLHQEPSLRPQYDTTAIAASLKKAISPQFEIVFAGAFSAGKSMLINALLERELLYSAEGHATGTECYIHYADVDQERVVLTFLSEAEIGEQVKALCDRLQIPAYTNINQPETIKFLTEQSHEIIKHEGGENRSDKAKQAKALLLLLEGFTHNRAHIKTLNYATYSMEQFNFSNLAEAATYARRGSNSSVLKKVEYYCHHSLLKDGNILVDTPGIDAPVKKDAELAYAKIQHPDTSAVVCVLKPASAGDMAIEETELLEKMRSNLGIRDRVFYVFNRIDQTWYAPQLRQRLDNLIQSEFRDISRVYKTSALLGFYASQIKHTNGSNRFGLDTIFAESVKQIGGEEENPQFVSEFNNYCANSGKLTRTDFKVSVHGYETPNQNYVRILNEWEQPLINQLIADSGIEDFRNAITRYLTEEKRPQLFAILADDLQPLCINLRQYYLDNYRELERQPRDIEAMKAQELTRLHQELKEVGIEFKNQIAHEVNEVIVKADAAFEQDFKKLQSRMVEYLDELVRNFSVQNANRRATLSHPRNQTVPLIAILVEALYYLANELEDVLIEETNRLIMAFYQRLLDRIRQSECYRKLFRLLGNDGGVEDQLKQVEKSVIDALVNEAKIECDRYVRESPRFYDEGQFSIYQFRQTLEKTTQGYDCSSIIEAEPAIRQLLKLDFDPKVSKTIQKDFRSAINLTLKTHLLPMADQQAELIFQQHDKAREYLGQSLDKEAQEKIERNEKSQSQIKDKIEEYNQAVSGINGCLQAMQVYERQLPLISQEDLKSKEILVEVCDENN

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Crispr_ID: NC_011726_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011726_13

4400686-4400797

TypeV-U4

Consensus_repeat	Method
TATTTTCATCCCATTTACGCGCTTGTTCTTCCCTATC	CRISPRCasFinder

1 spacers

c2c9_V-U4

The CRISPR arrays of NC_011726_13

>merge|NC_011726|13|4400686-4400797|CRISPRCasFinder
TATTTTCATCCCATTTACGCGCTTGTTCTTCCCTATCGCGCTCTAATTGGTCTAAAATCCGATCCCATTTACGGGTGTTTTCATCCCATTTATGGGTATTTTCATCCCATTT

>NC_011726|13|12|4400686-4400797|CRISPRCasFinder
TATTTTCATCCCATTTACGCGCTTGTTCTTCCCTATC	GCGCTCTAATTGGTCTAAAATCCGATCCCATTTACGGG
TGTTTTCATCCCATTTATGGGTATTTTCATCCCATTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011726.1\|WP_015785172.1\|4398176_4398527_-\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_015957312.1\|4403240_4404551_-\|phytase	unknown	unknown	gnl\|CDD\|226698
NC_011726.1\|WP_015785178.1\|4406265_4408059_-\|translational-GTPase-TypA	unknown	unknown	gnl\|CDD\|224138
NC_011726.1\|WP_015785164.1\|4390863_4391796_-\|DUF1460-domain-containing-protein	unknown	unknown	gnl\|CDD\|369314
NC_011726.1\|WP_015785181.1\|4410955_4413385_+\|dynamin-like-GTPase-family-protein	unknown	unknown	gnl\|CDD\|223771
NC_011726.1\|WP_015785165.1\|4391924_4392473_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|238182
NC_011726.1\|WP_015785168.1\|4394662_4394872_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_015785173.1\|4398911_4400186_+\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_011726.1\|WP_015957313.1\|4404943_4406155_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	c2c9_V-U4	-	gnl\|CDD\|223747
NC_011726.1\|WP_015785170.1\|4395910_4396852_-\|PhzF-family-phenazine-biosynthesis-protein	unknown	unknown	gnl\|CDD\|223461
NC_011726.1\|WP_015785176.1\|4402901_4403087_-\|DUF4926-domain-containing-protein	unknown	unknown	gnl\|CDD\|379816
NC_011726.1\|WP_015785175.1\|4401685_4402951_+\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_011726.1\|WP_015785180.1\|4410430_4410856_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NC_011726.1\|WP_015957311.1\|4394928_4395756_-\|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl\|CDD\|223740
NC_011726.1\|WP_015785183.1\|4414123_4414387_+\|hypothetical-protein	unknown	unknown	unknown
NC_011726.1\|WP_015785182.1\|4413623_4413962_+\|KGK-family-protein	unknown	unknown	gnl\|CDD\|370166
NC_011726.1\|WP_015785171.1\|4396880_4398134_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|274425
NC_011726.1\|WP_015785167.1\|4392899_4394426_-\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NC_011726.1\|WP_015785179.1\|4408480_4410430_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224720
NC_011726.1\|WP_015957310.1\|4392575_4392842_+\|MoaD/ThiS-family-protein	unknown	unknown	gnl\|CDD\|340452

Protein	Function_ID	Function_description	E-value
NC_011726.1\|WP_015785179.1\|4408480_4410430_+\|hypothetical-protein	gnl\|CDD\|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	0.000144024
NC_011726.1\|WP_015785178.1\|4406265_4408059_-\|translational-GTPase-TypA	gnl\|CDD\|224138	COG1217, TypA, Predicted membrane GTPase involved in stress response [Signal transduction mechanisms].	0
NC_011726.1\|WP_015785164.1\|4390863_4391796_-\|DUF1460-domain-containing-protein	gnl\|CDD\|369314	pfam07313, DUF1460, Protein of unknown function (DUF1460). This family consists of several hypothetical bacterial proteins of around 260 residues in length. The function of this family is unknown.	1.70966e-63
NC_011726.1\|WP_015785181.1\|4410955_4413385_+\|dynamin-like-GTPase-family-protein	gnl\|CDD\|223771	COG0699, COG0699, Predicted GTPases (dynamin-related) [General function prediction only].	2.49847e-26
NC_011726.1\|WP_015785165.1\|4391924_4392473_-\|universal-stress-protein	gnl\|CDD\|238182	cd00293, USP_Like, Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, athough Usp lacks ATP-binding activity.	9.29379e-31
NC_011726.1\|WP_015785180.1\|4410430_4410856_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.36075e-12
NC_011726.1\|WP_015785173.1\|4398911_4400186_+\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	4.80644e-110
NC_011726.1\|WP_015957313.1\|4404943_4406155_+\|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.8478e-55
NC_011726.1\|WP_015785170.1\|4395910_4396852_-\|PhzF-family-phenazine-biosynthesis-protein	gnl\|CDD\|223461	COG0384, COG0384, Predicted epimerase, PhzC/PhzF homolog [General function prediction only].	8.29459e-105
NC_011726.1\|WP_015785176.1\|4402901_4403087_-\|DUF4926-domain-containing-protein	gnl\|CDD\|379816	pfam16277, DUF4926, Domain of unknown function (DUF4926). This family consists of uncharacterized proteins around 70 residues in length and is mainly found in various Caulobacter, Microcystis and Cyanothece species. The function of this family is unknown.	1.19471e-07
NC_011726.1\|WP_015785175.1\|4401685_4402951_+\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.27969e-100
NC_011726.1\|WP_015785171.1\|4396880_4398134_-\|glycosyltransferase	gnl\|CDD\|274425	TIGR03087, stp1, sugar transferase, PEP-CTERM/EpsH1 system associated. Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.	2.29309e-47
NC_011726.1\|WP_015957311.1\|4394928_4395756_-\|mechanosensitive-ion-channel-family-protein	gnl\|CDD\|223740	COG0668, MscS, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	9.90974e-42
NC_011726.1\|WP_015785182.1\|4413623_4413962_+\|KGK-family-protein	gnl\|CDD\|370166	pfam08872, KGK, KGK domain. This presumed domain is found in one or two copies in cyanobacterial proteins. It is named after a short sequence motif.	7.1885e-24
NC_011726.1\|WP_015957312.1\|4403240_4404551_-\|phytase	gnl\|CDD\|226698	COG4247, Phy, 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) [Lipid metabolism].	1.43933e-120
NC_011726.1\|WP_015785167.1\|4392899_4394426_-\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	2.97025e-50
NC_011726.1\|WP_015957310.1\|4392575_4392842_+\|MoaD/ThiS-family-protein	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	4.40035e-25

>NC_011726.1|WP_015785173.1|4398911_4400186_+|insulinase-family-protein
MVQLIDRFKTVPYPANLIQLDHGLTLIHQYQPATPVAVVDVWVKAGTIVEPDNWSGMAHFLEHMIFKGSKRVLPGIFDQMIENSGGMANAATSYDYAHFFLTTAAEYLPDTLPYLAEILLHAEIPDEEFVRERDVVLEEIRSCYDDPDWLAFQSLCESLYQRHPYGRSILGHESQLLQHSPHQMRCFHRTHYQPDKMTVVVVGNLQEEVVLKLVNQEFGEFSAPSECPPIQTLAEPPLLEVRRTQMYLPRLEQARLLMGWIGPGVDCLEDGFGLDLISAILGVGRSSRLVQQLREQKHLVLDVESSFSLQRDSSLFTIAAWLDPQDLEIVEQLILDNLMELQVKPVTEEELERGKRLLCHDYIFSTETPGQLAGLYGYYQTIASAEVSLSYPRIIEQFSAKDLQRIADQYLSPERYAITVMQPC
>NC_011726.1|WP_015785172.1|4398176_4398527_-|hypothetical-protein
MTEREFQTIIDKLDSLENKVIKVDQDNQLLSEKLELYREEAKLEAKLLAEKLELYQKVSQEKLEAFQEANKQQIEANRQQIQAFQEANKQQLNVSLGVLVTAAVTILASVILGMSH
>NC_011726.1|WP_015785171.1|4396880_4398134_-|glycosyltransferase
MKILILSCAFPYPPLEGKTQMRTFSFLKYLNQRHDITFVTQASDEVLEEDIASLKQEIPNCIIFPDVTQETTSPRFLEKAKRLGVFFQQGTPPKLLSHYSLKLQEYLDQEIDSGQFDLLTCEGNNGEIYIRPEWQKKLPTVINIHRSLWGVYKHQRENHSGESGLRNQINLPLLRRYEKHYCSKFSAIVTATQTEQKLLKNLKLETPITVVPNGLDLSVFPKRPANSGGQRIIFIGAMDKPANIDAARFFSLEVFPKIRQRYPESILELVGIRPVHEVLELGEYPGIKVTGPVSSMIEYLHWATVCVIPLRKSMGTKIRTLQALATGTPLVASDYGLEGLSVDGTGVPLCAMRANEIDEYVYAIGRLFEQPKLREKLSINGRTLIENEYTWKRMGERYEQILLTTYNTSHKLSDNSP
>NC_011726.1|WP_015785170.1|4395910_4396852_-|PhzF-family-phenazine-biosynthesis-protein
MNLTQQYKFYTLDVFTDQIFGGNPLAVFPKAQGLTDEQMQKVAAEFNLSETVFVLPPETSKGTRKLRIFTPKVELPFAGHPTVGTAYLLSYLGEIDQPEEPDTDLSIIFEEGVGLVPVTIKIKQGKPVYTELQAAQLPEVKNDAPSIQELAEILGLEITDFREDQYSPQGVSCGVPFLLIPLQNRTALGRINFNRDRWQHILGKAWASAMYVFCDDPETEGTHLRSRMFAPAMGITEDPATGSAATAFGAYLALRHPLTEGTLQWRIEQGLEMGRPSILEVAVEKHQGEIREIRVGGSSVLVSEGTMTIPLVR
>NC_011726.1|WP_015957311.1|4394928_4395756_-|mechanosensitive-ion-channel-family-protein
MDAVPVQVNVVIETLKTQVTGFGLKLIGAILLWVIGQWLITKGVNLLAKVLKKQNIEPTLIAYVNNFLGIGLKIVLIVAILGYFGIETTSFAALLAAAGVAIGAAWGGLLANFAAGIFLVIFRPFSVGDFVCAGGVTGTVEEIGLFVTSINTIDNVRNIIGNNKIFADNIQNFTANPYRRVDLVAQLNHSVNYGEAINRLKATVSQIPNVIDHPSPEIEILEFNLAGPVLAVRPYCHNDHYWQVYFDTNKAIRETLGDAYPVPEQHYVIRQTSAI
>NC_011726.1|WP_015785168.1|4394662_4394872_+|hypothetical-protein
MNSHDLAKYIEAHEGITKPWLLIQLRLKKIQENRDKMSEQEYLTHIESLHQDLMKLGEWWVGIEDEVFQ
>NC_011726.1|WP_015785167.1|4392899_4394426_-|SagB/ThcOx-family-dehydrogenase
MSKSLTSIATHYHQRTKYHPETIARKSQGLDWSKQPSVFKQYKIGTSYDLTVYLSDKATSDEHTPYWRRLSRFLACSYGLTAKIPTMGEPLYLRAAPSAGGLYPAEVYLISRGTPQLPAGLYHYQPQTHSLIYFWESDVWSNLQEACAWDLDLEDAQLAIITTAIFYRSAWRYEDRAYRRILLDTGHLLGNIELAAAINHYRPHLIGGFSDYIINELLYLDPDQEAGITVISLKDLLNPQQNPSQSFKTTTLPSEIHTDYPSISDGELLYYFHQATEIRISERLPDATLSNEISNLEDKYNFPFCLKVSTKTKPINWGENLLNLEQTILKRRSTRAYTGANLTLEELNSLLNFTYQAQDYEDIGLDADPDYFDLSLIETFIAVSGVNGLEEGCYYYAPKAQELRQIRFKNFRQELHYLCLGQELGRDAAAVIFHTADLEKAVQKYGDRAYRYLHLDAGHLGQRLNLAAIELNLGVSGIGGFFDDQVNEVLGIPSDEAVLYITTLGRPH
>NC_011726.1|WP_015957310.1|4392575_4392842_+|MoaD/ThiS-family-protein
MDHHALNIQITIKLFAAYQDSYGVPELQREFPNQTTVKGVLDSLIHEHPELETWRDVTRFGVNFKFVEADTLLKDGDEVVLIPPVSGG
>NC_011726.1|WP_015785165.1|4391924_4392473_-|universal-stress-protein
MTNQVESRDTLTQPNPEPQVATVPYQKILVAVDYLADTPKVFEEALNLAKLNHSQLMIFYCIQGRIPGSIDLPIYAGMISYGGIYSQEMVELEEKVIEESTEELKAWLQRLTDEATQEGLKAAADYSYGEPGRQICSLAKNWGSDLIVVGRRGRSGLAELFLGSISNYVVHHSPCAVLVVQQ
>NC_011726.1|WP_015785164.1|4390863_4391796_-|DUF1460-domain-containing-protein
MKKILLPVLVPLFILISPQDVLPLQSQDQSLEYVQKRSQNSLAQVKQNSLEESKTKKEFKQIISHLKEQNFSDLSLGQTVQKVAEQFLGAAYIAGLLDKSEQEKLFISLKEFDCVLFVETVLGLSQNISRQETQYENFVKNIQDLRYANGIIDGYCSRLHYFSDWINDNQKRGNVKNITAELGGIKFDKTLTFMSKNRKLYPKLINNQANYQCILEREKQLNQLDLYYIPHNQIKAIYQKLQPGDIIAIATNIDGLDVTHTGLIYRTSEGNIAFIHASPAGQVTIAQDLQTYAQNVKNAVGIIVARPLTK
>NC_011726.1|WP_015785175.1|4401685_4402951_+|insulinase-family-protein
MNRYQIQGIGEKQAVHRLRLDNGVVLIVGENPTADLIAGRIFLKNAGSLWESKEKAGLSNLLATVITKGTERLSSGEIAEAVESIGASLGANAASDYFMMGIKTVSSDFAFILALMGEILRSPTFPEAEVALEKHLIIQSIRSQQEQPFNVAFNQLRGLMYQEHPYGFSILGTEETVSQLCRDDLINYHNYHFRPDNLIISLSGRITLHDAISLVEKTLGDWEVPSHTLTPLSLPPLISSPVEKITFQETQQSIVMLGYLTGGVKSPEYPVLKLLSTYLGNGLSSRLFVELREKRGLAYDVSALYPTRLEPSQFVVYMGTAPDNTSIAIEGLQQECERLCYQELTPEELQGAKNKLLGQYALGKQTNSEIAQLYGWYETLGLGVEFDQEFQAMITEVTSQIAQSVAKNYLLSPYLSVVGPN
>NC_011726.1|WP_015785176.1|4402901_4403087_-|DUF4926-domain-containing-protein
MKLLESVTLLKKISKLNLYWGQVGTIVEEYQPQVFEVELSDTLFRINWVPQRKDREKVNNF
>NC_011726.1|WP_015957312.1|4403240_4404551_-|phytase
MNKIINSLAVACFSFAFSHQAAIAVQLATPTAETPPVIDEIVDPPGDADDPAIWLHPNDPSQSLVLGTLKNAGLGVYDLGGNLLQLIQPNSIRYNNVDLLYGFSLGGNSVDLAIASDRQNDILAIFKIDPMTRLLESIVSNNIGTIFTPVGQVSNGTTTAYGLATYTDLSTGKNYVFVSQRETGNVAQLELFDDGTGKVNYTQVRSLTLPIPPGGVLEDAQVEGMVADRELGYVYVGQENRGIWKFSASPNGSTLGQLIDAVKPEGTHLEADVEGLTIYYSDNGTGYLLASSQGDNTFAIYDRLGNNNYLGSFSIVASGGIDSVEESDGADVINVPLGSQFPFGLFVTQDGSNDPPELFFDPDDQEFVNVSSNFKFVPWETIANAFAPNPLLINTSSFDPRNPSSITVPEPTLSIWGLFVMLGVGYLKRGKNHPFR
>NC_011726.1|WP_015957313.1|4404943_4406155_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MKQRLKFRIYPTTSQKTALAKLFGCTRVVWNDALAHCQQEYREGRKKPNNTQLSSRLTQLKKTEEKIWLGEVSAIPLQQSLRDLEVAYSNFFKSCQGKRKGKKVKSPKFKSRKFRQSARFTDNGFKINQQNVYLAKIGKLKIVWSRELPSKPSSVTVIKDSANRYFLSFVCDVNSSPLAPNNNSIGIDLGIIDFATLNNGEKIKSPKPLKHNLKQLRRLQKNLSRKQKGSKRHEVARLKVAKLHAKITDIRTDFLHQLSTKLIRENQTIALEDLNASGMVKNRKLSRAISDLGWRSFRTMLETKGEIYGRDVRIINRWEATSQTCSSCGFKGGKKELNIREWTCLNCGAVHDRDVNAATNILKVAGGHPETKNGRGEKIRLSNKKAHLSEASTTPQYKQLSLF
>NC_011726.1|WP_015785178.1|4406265_4408059_-|translational-GTPase-TypA
MSLPIRNVAIIAHVDHGKTTLVDALLKQSGIFREGEDIPDCVMDSNTLERERGITILSKNTAVRYNDTLINIVDTPGHADFGGEVERVLGMVDGCILIVDANEGPMPQTRFVLKKALEKGLRPIVVVNKIDRPQADPNIAVDKVFDLFVELGADDDQCDFTTLFASGLSGYAKETLEEEGVDMKPLFEAILHHVPPPAGDVNKPLQLQVTTLDYSDYLGRIIIGRIHNGTIKAGQQAALMKEDGSIVRGKISKLLGFEGLQRVEMQEASAGYIVAVAGFADANIGETLTCPNEPQALPLIKVDEPTLQMTFSVNDSPFAGQEGKFVTSRQIRDRLHRELETNVALRVEDTDSPDKFAVSGRGELHLGILIETMRREGYEFQVSQPQVIYREVNGQPCEPYEYLVLDVPEEAVGASIERLGQRKGEMQDMQTGTNGRTQLEFVVPARGLIGFRGEFIRLSRGEGIMNHSFLEYRPFSGELATRYNGVITSFEEGVATFYALQNAEDRGVFFITPGTKVYKGMIIGESNRPQDVELNICKTKQLTNHRSATGDELVQLQAPEEMSLERALEYIGPDELVEVTPQSIRLRKMKAQKLVKR
>NC_011726.1|WP_015785179.1|4408480_4410430_+|hypothetical-protein
MAVILPLIALVLLLLIFYKKTNYFRHSLLSSSICWGLLLTIITEVLSLIQSLVFSYLSLGWGFINILLIFIYLNIKLTKHKKKIDLKKIFYKLSNFWIIIVLGVTFVVTIVGLTALISPPNNRDSMDYHMARVAYWIQNHSLNHYPTHYLAQLYQGPLAELIIVNLQILSGGDYLANLVQWLSLIGSLLGVSLIAKLLGADLWGQLFSAVVAATIPMGILQGSSTQNDYVASFWLVCLTYFVLLNVKGQRNWSNFLQLSFSLGLAILTKGTSYIYALPLIIWFLLSELKYLKWQIWKPTLMLGIVVFIINLGHYSRNYLLFGKIIFTGNKYTNDAFSLPIFISNFIRNIALHLRTPVQSFNFLLQKVVSLIHQILGIDISDIRTTWSGQEFQLYFPSGQEAVSSLLHENLAANTLHLLLIVGAIFILFFQGKYKKDKLLFYYCIILISMFFLFCLLLKWQPWNSRLHLPIFVLFSPFSGSVFSRFKSRSFITFLSIFLIISSFPWVFFNTSRPIISNLKTESILTTSRTNQYFNNWPTIKNPYLKATGYINSQECSKIGLTRDFQVWQYPLFIFIKPTTSNPLEIRNINVTNISSEKMKVEPYKHFIPCAIISLNFPDQKKKISKEINTNTGTYSIKFSSRLINVFMKQ
>NC_011726.1|WP_015785180.1|4410430_4410856_-|GNAT-family-N-acetyltransferase
MKDKVKIITQVNDSQIKDLYQLYQLSWWSQGRMLDGIKIMLENSDLIIGLSHCETEKLIGFARVLTDYVYRATIWDVMVDPSYQKKGLGSLLMESIMNHQSLRNVECFSLMCLPEAIPFYEKFEFATYHKPIEIMIRSRHS
>NC_011726.1|WP_015785181.1|4410955_4413385_+|dynamin-like-GTPase-family-protein
MTELVPQCQNLSTQVNSLLELLHQEPSLRPQYDTTAIAASLKKAISPQFEIVFAGAFSAGKSMLINALLERELLYSAEGHATGTECYIHYADVDQERVVLTFLSEAEIGEQVKALCDRLQIPAYTNINQPETIKFLTEQSHEIIKHEGGENRSDKAKQAKALLLLLEGFTHNRAHIKTLNYATYSMEQFNFSNLAEAATYARRGSNSSVLKKVEYYCHHSLLKDGNILVDTPGIDAPVKKDAELAYAKIQHPDTSAVVCVLKPASAGDMAIEETELLEKMRSNLGIRDRVFYVFNRIDQTWYAPQLRQRLDNLIQSEFRDISRVYKTSALLGFYASQIKHTNGSNRFGLDTIFAESVKQIGGEEENPQFVSEFNNYCANSGKLTRTDFKVSVHGYETPNQNYVRILNEWEQPLINQLIADSGIEDFRNAITRYLTEEKRPQLFAILADDLQPLCINLRQYYLDNYRELERQPRDIEAMKAQELTRLHQELKEVGIEFKNQIAHEVNEVIVKADAAFEQDFKKLQSRMVEYLDELVRNFSVQNANRRATLSHPRNQTVPLIAILVEALYYLANELEDVLIEETNRLIMAFYQRLLDRIRQSECYRKLFRLLGNDGGVEDQLKQVEKSVIDALVNEAKIECDRYVRESPRFYDEGQFSIYQFRQTLEKTTQGYDCSSIIEAEPAIRQLLKLDFDPKVSKTIQKDFRSAINLTLKTHLLPMADQQAELIFQQHDKAREYLGQSLDKEAQEKIERNEKSQSQIKDKIEEYNQAVSGINGCLQAMQVYERQLPLISQEDLKSKEILVEVCDENN
>NC_011726.1|WP_015785182.1|4413623_4413962_+|KGK-family-protein
MSEDKLFEINEYLEGDDDVIAFRDSSTYKISKLKTFLIEKIKSIRYKVGMSWNDSIFTSYGRECEILKVGSGGWIKGQLKFRMILEFIPDEPELKEPESPLDEIRKKISEMG
>NC_011726.1|WP_015785183.1|4414123_4414387_+|hypothetical-protein
MTEQEQLTRILTLVELTNSRLDKLDSDIKETNKRIEDEVKRWDERFFQLVKEQGQTARTIIIAAASVVVLSPVLGAIADVFTHFVSK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_011726_8	8.1\|3093055\|42\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	3093055-3093096	42	NC_011721.1	37332-37373	0	1.0

1. spacer 8.1|3093055|42|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to position: 37332-37373, mismatch: 0, identity: 1.0

ttatgttgcgtaaaggaagggtgagtagtcggaatttctcgg	CRISPR spacer
ttatgttgcgtaaaggaagggtgagtagtcggaatttctcgg	Protospacer
******************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011726_8	8.1\|3093055\|42\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	3093055-3093096	42	NC_011721	Rippkaea orientalis PCC 8801 plasmid pP880101, complete sequence	37332-37373	0	1.0
NC_011726_8	8.1\|3093055\|42\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	3093055-3093096	42	NC_013160	Rippkaea orientalis PCC 8802 plasmid pP880201, complete sequence	21912-21953	0	1.0
NC_011726_2	2.1\|604819\|27\|NC_011726\|PILER-CR	604819-604845	27	NC_014839	Pantoea sp. At-9b plasmid pPAT9B02, complete sequence	291778-291804	6	0.778
NC_011726_10	10.32\|4330825\|35\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4330825-4330859	35	MN694411	Marine virus AFVG_250M1188, complete genome	16358-16392	7	0.8
NC_011726_10	10.32\|4330825\|35\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4330825-4330859	35	MN693004	Marine virus AFVG_117M22, complete genome	16340-16374	7	0.8
NC_011726_12	12.1\|4398282\|27\|NC_011726\|CRISPRCasFinder	4398282-4398308	27	NZ_LT991956	Enterobacter hormaechei subsp. steigerwaltii isolate C309 plasmid pC309-p2	124548-124574	7	0.741
NC_011726_10	10.8\|4329068\|32\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4329068-4329099	32	MN693927	Marine virus AFVG_250M888, complete genome	5106-5137	9	0.719
NC_011726_10	10.27\|4330460\|36\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4330460-4330495	36	KT997859	Uncultured Mediterranean phage uvDeep-CGR2-KM19-C184, complete genome	18287-18322	9	0.75
NC_011726_10	10.27\|4330460\|36\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4330460-4330495	36	NZ_CP032703	Pantoea dispersa strain DSM 32899 plasmid unnamed1, complete sequence	279612-279647	9	0.75
NC_011726_10	10.31\|4330751\|37\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4330751-4330787	37	NZ_CP031069	Bacillus sp. JAS24-2 plasmid pl626, complete sequence	346787-346823	9	0.757
NC_011726_10	10.6\|4328923\|34\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4328923-4328956	34	NZ_CP023312	Vibrio anguillarum strain VIB12 isolate Sea bass plasmid p292, complete sequence	181355-181388	10	0.706
NC_011726_10	10.26\|4330389\|34\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4330389-4330422	34	MN692976	Marine virus AFVG_117M2, complete genome	3190-3223	10	0.706
NC_011726_10	10.31\|4330751\|37\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4330751-4330787	37	NZ_CP053953	Bacillus cereus strain FDAARGOS_798 plasmid unnamed2, complete sequence	221058-221094	10	0.73
NC_011726_10	10.31\|4330751\|37\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4330751-4330787	37	NZ_CP053950	Bacillus cereus strain FDAARGOS_799 plasmid unnamed2, complete sequence	115305-115341	10	0.73
NC_011726_4	4.7\|912438\|36\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	912438-912473	36	NZ_KT897276	Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence	62644-62679	11	0.694
NC_011726_4	4.7\|912438\|36\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	912438-912473	36	NZ_KT897280	Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence	64604-64639	11	0.694
NC_011726_4	4.7\|912438\|36\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	912438-912473	36	NZ_KT897275	Clostridium botulinum strain IFR 12/29 plasmid p12/29, complete sequence	61605-61640	11	0.694
NC_011726_4	4.7\|912438\|36\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	912438-912473	36	NZ_KT897277	Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence	62644-62679	11	0.694
NC_011726_4	4.7\|912438\|36\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	912438-912473	36	NZ_KT897278	Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence	64604-64639	11	0.694
NC_011726_4	4.7\|912438\|36\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	912438-912473	36	NZ_KT897279	Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence	64604-64639	11	0.694
NC_011726_10	10.38\|4331254\|38\|NC_011726\|PILER-CR,CRISPRCasFinder,CRT	4331254-4331291	38	NC_007766	Rhizobium etli CFN 42 plasmid p42f, complete sequence	842-879	11	0.711

1. spacer 8.1|3093055|42|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NC_011721 (Rippkaea orientalis PCC 8801 plasmid pP880101, complete sequence) position: , mismatch: 0, identity: 1.0

ttatgttgcgtaaaggaagggtgagtagtcggaatttctcgg	CRISPR spacer
ttatgttgcgtaaaggaagggtgagtagtcggaatttctcgg	Protospacer
******************************************

2. spacer 8.1|3093055|42|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NC_013160 (Rippkaea orientalis PCC 8802 plasmid pP880201, complete sequence) position: , mismatch: 0, identity: 1.0

ttatgttgcgtaaaggaagggtgagtagtcggaatttctcgg	CRISPR spacer
ttatgttgcgtaaaggaagggtgagtagtcggaatttctcgg	Protospacer
******************************************

3. spacer 2.1|604819|27|NC_011726|PILER-CR matches to NC_014839 (Pantoea sp. At-9b plasmid pPAT9B02, complete sequence) position: , mismatch: 6, identity: 0.778

tgcagcataggcagccgaaaattcagg	CRISPR spacer
tgcagcataggcagccgaaaaaatgca	Protospacer
*********************  .. .

4. spacer 10.32|4330825|35|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to MN694411 (Marine virus AFVG_250M1188, complete genome) position: , mismatch: 7, identity: 0.8

ctttagctgtttttgcaggtcgtttaaccgctttt	CRISPR spacer
ttttagctgtttttgcagatcgtttaaatgcacct	Protospacer
.*****************.******** .** ..*

5. spacer 10.32|4330825|35|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to MN693004 (Marine virus AFVG_117M22, complete genome) position: , mismatch: 7, identity: 0.8

ctttagctgtttttgcaggtcgtttaaccgctttt	CRISPR spacer
ttttagctgtttttgcagatcgtttaaatgcacct	Protospacer
.*****************.******** .** ..*

6. spacer 12.1|4398282|27|NC_011726|CRISPRCasFinder matches to NZ_LT991956 (Enterobacter hormaechei subsp. steigerwaltii isolate C309 plasmid pC309-p2) position: , mismatch: 7, identity: 0.741

ttgtatttgttgccgattagcctctat	CRISPR spacer
gctgatttgttgccgatcagcctctgg	Protospacer
 .  *************.*******.

7. spacer 10.8|4329068|32|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to MN693927 (Marine virus AFVG_250M888, complete genome) position: , mismatch: 9, identity: 0.719

tttttcagccaatttttgactcttgaagtccg	CRISPR spacer
gtactgcaccagttcttgactcttgaagtcca	Protospacer
 * .*  .***.**.****************.

8. spacer 10.27|4330460|36|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to KT997859 (Uncultured Mediterranean phage uvDeep-CGR2-KM19-C184, complete genome) position: , mismatch: 9, identity: 0.75

agtaacggtggttttgccgtcttcatcggtaacagt	CRISPR spacer
acctgtggtggtgttgccgtcttcatcggtaacgtc	Protospacer
* . ..****** ********************. .

9. spacer 10.27|4330460|36|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032703 (Pantoea dispersa strain DSM 32899 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.75

agtaacggtggttttgccgtcttcatcggtaacagt	CRISPR spacer
gatcgcggtgatttttccgtcttcatcggtacctat	Protospacer
..* .*****.**** *************** * .*

10. spacer 10.31|4330751|37|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP031069 (Bacillus sp. JAS24-2 plasmid pl626, complete sequence) position: , mismatch: 9, identity: 0.757

gtaacgctcccccaattaatccagccccaactgtaat	CRISPR spacer
ctaaatgtgatccaataaatccagccccacctgtaat	Protospacer
 ***   *  .***** ************ *******

11. spacer 10.6|4328923|34|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023312 (Vibrio anguillarum strain VIB12 isolate Sea bass plasmid p292, complete sequence) position: , mismatch: 10, identity: 0.706

aaatcgttattgttatgcaaaatttctttgccct	CRISPR spacer
gaatcggtattgtgatgcaaaatttcccgttcgc	Protospacer
.***** ****** ************..  .* .

12. spacer 10.26|4330389|34|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to MN692976 (Marine virus AFVG_117M2, complete genome) position: , mismatch: 10, identity: 0.706

ttttatggcaacggctttatcttttaaggataaa	CRISPR spacer
acctgacgcaacggctttaacttttaaagatgca	Protospacer
 ..*.  ************ *******.***. *

13. spacer 10.31|4330751|37|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053953 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.73

gtaacgctcccccaattaatccagccccaactgtaat	CRISPR spacer
ccaaatgtgatccaataaatccagccccacctgtaat	Protospacer
 .**   *  .***** ************ *******

14. spacer 10.31|4330751|37|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053950 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.73

gtaacgctcccccaattaatccagccccaactgtaat	CRISPR spacer
ccaaatgtgatccaataaatccagccccacctgtaat	Protospacer
 .**   *  .***** ************ *******

15. spacer 4.7|912438|36|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897276 (Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence) position: , mismatch: 11, identity: 0.694

atcgtgactttttcaggcttttcatctttatccttg	CRISPR spacer
gaagaaactttttcagtattttcatctttatcagaa	Protospacer
.  * .**********  **************   .

16. spacer 4.7|912438|36|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897280 (Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence) position: , mismatch: 11, identity: 0.694

atcgtgactttttcaggcttttcatctttatccttg	CRISPR spacer
ggagaaactttttcagtattttcatctttatcagaa	Protospacer
.  * .**********  **************   .

17. spacer 4.7|912438|36|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897275 (Clostridium botulinum strain IFR 12/29 plasmid p12/29, complete sequence) position: , mismatch: 11, identity: 0.694

atcgtgactttttcaggcttttcatctttatccttg	CRISPR spacer
gaagaaactttttcagtattttcatctttatcagaa	Protospacer
.  * .**********  **************   .

18. spacer 4.7|912438|36|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897277 (Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence) position: , mismatch: 11, identity: 0.694

atcgtgactttttcaggcttttcatctttatccttg	CRISPR spacer
gaagaaactttttcagtattttcatctttatcagaa	Protospacer
.  * .**********  **************   .

19. spacer 4.7|912438|36|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897278 (Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence) position: , mismatch: 11, identity: 0.694

atcgtgactttttcaggcttttcatctttatccttg	CRISPR spacer
ggagaaactttttcagtattttcatctttatcagaa	Protospacer
.  * .**********  **************   .

20. spacer 4.7|912438|36|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897279 (Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence) position: , mismatch: 11, identity: 0.694

atcgtgactttttcaggcttttcatctttatccttg	CRISPR spacer
ggagaaactttttcagtattttcatctttatcagaa	Protospacer
.  * .**********  **************   .

21. spacer 10.38|4331254|38|NC_011726|PILER-CR,CRISPRCasFinder,CRT matches to NC_007766 (Rhizobium etli CFN 42 plasmid p42f, complete sequence) position: , mismatch: 11, identity: 0.711

ggcgaaaatgaagacgacgacgatgtggtgacggaaat	CRISPR spacer
gacgaaaatggagacgacgacgatgtcgttttcggccc	Protospacer
*.********.*************** **  . *.  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

323259 : 386344

uncultured_Mediterranean_phage(22.22%)

protease,transposase,integrase

attL 324248:324264|attR 395279:395295

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012593702.1\|323259_323745_+\|protease	hydrogenase maturation protease	NA	NA	NA	NA
324248:324264	attL	NA	NA	NA	NA
WP_012593703.1\|325324_326176_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_012593704.1\|326245_327139_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_012593705.1\|327231_328449_+	DUF790 family protein	NA	NA	NA	NA
WP_012593706.1\|328454_329228_-	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	NA	NA	NA	NA
WP_012593707.1\|329566_331486_+	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	5.4e-37	25.6
WP_012593708.1\|331542_331992_+	hypothetical protein	NA	NA	NA	NA
WP_012593709.1\|332299_332872_+	late competence development ComFB family protein	NA	NA	NA	NA
WP_012593710.1\|332949_333603_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_012593711.1\|333853_334342_+	anti-sigma factor	NA	NA	NA	NA
WP_012593712.1\|334301_334748_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_012593713.1\|334903_335509_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_012796756.1\|335745_336012_-	hypothetical protein	NA	NA	NA	NA
WP_012593715.1\|336152_337238_-	3-isopropylmalate dehydrogenase	NA	NA	NA	NA
WP_012593716.1\|337363_337648_-	RNA-binding protein	NA	NA	NA	NA
WP_012593718.1\|338034_338424_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012593719.1\|338573_338882_+	hypothetical protein	NA	NA	NA	NA
WP_012593720.1\|339008_339353_+	4a-hydroxytetrahydrobiopterin dehydratase	NA	NA	NA	NA
WP_012593721.1\|339360_339963_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_012593722.1\|340245_341079_-	uridylate kinase	NA	NA	NA	NA
WP_012593723.1\|341157_341997_-	uridine monophosphate kinase	NA	NA	NA	NA
WP_012593724.1\|342014_342839_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_012593725.1\|343168_343627_+	DUF2141 domain-containing protein	NA	NA	NA	NA
WP_012593726.1\|343791_344292_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_012593727.1\|344303_345767_+	carotenoid oxygenase family protein	NA	NA	NA	NA
WP_012593728.1\|345767_346583_-	UDP-3-O-acyl-N-acetylglucosamine deacetylase	NA	NA	NA	NA
WP_012593729.1\|346605_347490_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_012593730.1\|347508_349767_-	BamA/TamA family outer membrane protein	NA	NA	NA	NA
WP_012593731.1\|349906_350638_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D7SJU7	Cyanophage	4.6e-45	44.9
WP_012593732.1\|350920_351190_+	hypothetical protein	NA	NA	NA	NA
WP_012593733.1\|351295_352321_+	ABC transporter permease	NA	NA	NA	NA
WP_012593734.1\|352411_354235_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012593735.1\|354293_355451_-	AAA family ATPase	NA	NA	NA	NA
WP_012593736.1\|355849_356920_+	potassium channel protein	NA	NA	NA	NA
WP_012593737.1\|357014_360035_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_012593738.1\|360053_360923_-	aspartoacylase	NA	NA	NA	NA
WP_012593739.1\|361270_361774_-	hypothetical protein	NA	NA	NA	NA
WP_012593740.1\|361951_363115_-	GuaB3 family IMP dehydrogenase-related protein	A0A1B1IS93	uncultured_Mediterranean_phage	4.5e-10	43.0
WP_012593741.1\|363256_364237_-	hypothetical protein	NA	NA	NA	NA
WP_012593742.1\|364537_366718_+	hemolysin-type calcium-binding protein	NA	NA	NA	NA
WP_012593743.1\|366701_367097_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_012593744.1\|367377_367830_+	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_041229581.1\|370338_370827_-	hypothetical protein	NA	NA	NA	NA
WP_012593748.1\|371252_372587_+\|transposase	transposase	A0A1L2BWU7	Bacteriophage	3.4e-86	46.3
WP_157861282.1\|372811_372985_-	hypothetical protein	NA	NA	NA	NA
WP_012593749.1\|373433_374405_+	solanesyl diphosphate synthase	NA	NA	NA	NA
WP_012593750.1\|374641_376639_+	AarF/ABC1/UbiB kinase family protein	C7U092	Ostreococcus_tauri_virus	2.5e-45	30.7
WP_012593751.1\|376817_377609_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_012593752.1\|377600_379124_-	anthranilate synthase component I	A0A0B5J984	Pandoravirus	6.4e-49	31.2
WP_012593753.1\|379326_379755_-	photosystem I protein PsaD	A0A0K0KWQ5	Prochlorococcus_phage	6.4e-39	53.6
WP_012593754.1\|380080_380851_-	hypothetical protein	NA	NA	NA	NA
WP_012593755.1\|380896_381364_-	DUF29 domain-containing protein	NA	NA	NA	NA
WP_012593756.1\|381428_382571_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	1.6e-52	34.0
WP_012593757.1\|382768_383710_+\|transposase	transposase	NA	NA	NA	NA
WP_012593758.1\|384156_385032_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_012796780.1\|385150_386344_+\|protease	trypsin-like serine protease	A0A1B1IT49	uncultured_Mediterranean_phage	5.4e-19	27.8
395279:395295	attR	NA	NA	NA	NA

DBSCAN-SWA_2

485090 : 492730

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012593847.1\|485090_485822_-	glutathione peroxidase	A0A1D8KSL1	Synechococcus_phage	2.4e-46	57.9
WP_012593848.1\|486018_486723_+	response regulator transcription factor	W8CYM9	Bacillus_phage	3.0e-41	44.2
WP_012593849.1\|486756_487851_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.8e-32	34.6
WP_012593850.1\|487890_488607_+	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_012593851.1\|488639_489530_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	4.8e-36	39.5
WP_012593852.1\|489526_490534_+	sulfotransferase family protein	NA	NA	NA	NA
WP_012593853.1\|490571_491645_+	glucose-1-phosphate thymidylyltransferase	G3MA50	Bacillus_virus	1.1e-39	38.3
WP_012593854.1\|491662_492730_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.4e-87	48.2

DBSCAN-SWA_3

2921018 : 2982955

Bacteriophage(25.0%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012596098.1\|2921018_2923457_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_012596099.1\|2923608_2924013_-	hypothetical protein	NA	NA	NA	NA
WP_012596100.1\|2924361_2924937_-\|transposase	transposase	NA	NA	NA	NA
WP_012596101.1\|2925022_2926129_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_012596102.1\|2926362_2926551_+	hypothetical protein	NA	NA	NA	NA
WP_012596103.1\|2926547_2926739_+	hypothetical protein	NA	NA	NA	NA
WP_012596104.1\|2926739_2927774_-	thiamine-phosphate kinase	NA	NA	NA	NA
WP_012596105.1\|2927868_2928147_-	hypothetical protein	NA	NA	NA	NA
WP_012596106.1\|2928352_2929366_+	DUF389 domain-containing protein	NA	NA	NA	NA
WP_012596107.1\|2929732_2931676_+	squalene--hopene cyclase	NA	NA	NA	NA
WP_012596108.1\|2931999_2933490_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_012596110.1\|2934327_2936262_-	hypothetical protein	NA	NA	NA	NA
WP_012596111.1\|2936622_2937402_+	photosystem II S4 domain protein	NA	NA	NA	NA
WP_012596112.1\|2937497_2938514_+	adenosyl-hopene transferase HpnH	NA	NA	NA	NA
WP_012596113.1\|2938590_2939028_+\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA
WP_012596114.1\|2939079_2941239_+	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
WP_012596115.1\|2941312_2941627_-	hypothetical protein	NA	NA	NA	NA
WP_012596117.1\|2942143_2942602_+	50S ribosomal protein L9	NA	NA	NA	NA
WP_012596118.1\|2943136_2944432_+	helix-turn-helix domain-containing protein	A0A1L2BWT9	Bacteriophage	1.8e-23	48.6
WP_012596119.1\|2944456_2946082_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.2e-155	54.3
WP_012596120.1\|2946208_2946520_-	co-chaperone GroES	A0A221S386	uncultured_virus	3.5e-18	50.5
WP_012596121.1\|2946775_2947411_+	DUF3782 domain-containing protein	NA	NA	NA	NA
WP_012596122.1\|2947475_2947964_-	hypothetical protein	NA	NA	NA	NA
WP_012596123.1\|2947960_2949076_-	ATP-binding protein	NA	NA	NA	NA
WP_012596124.1\|2949229_2949832_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_012596125.1\|2949999_2950293_+	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_012596126.1\|2950385_2950493_+	photosystem II reaction center protein M	NA	NA	NA	NA
WP_012596127.1\|2950662_2951565_+	J domain-containing protein	NA	NA	NA	NA
WP_012596128.1\|2952146_2953277_+	DegT/DnrJ/EryC1/StrS family aminotransferase	E5ES42	Bathycoccus_sp._RCC1105_virus	3.3e-50	33.6
WP_012596129.1\|2953379_2954348_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_012596130.1\|2954453_2956091_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_012596131.1\|2956139_2957549_-	anthranilate synthase component I	S4VNU7	Pandoravirus	8.3e-35	35.4
WP_012596132.1\|2957580_2958453_-	hypothetical protein	NA	NA	NA	NA
WP_012596133.1\|2958528_2960166_+	DUF655 domain-containing protein	NA	NA	NA	NA
WP_012596134.1\|2960231_2961137_-	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_012596135.1\|2961218_2962700_-	TM0106 family RecB-like putative nuclease	NA	NA	NA	NA
WP_012596137.1\|2963138_2963816_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_012596138.1\|2963957_2964185_+	hypothetical protein	NA	NA	NA	NA
WP_012596139.1\|2964478_2965762_+\|transposase	transposase	A0A1L2BWT9	Bacteriophage	5.3e-28	51.7
WP_012596140.1\|2965859_2966456_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_012596141.1\|2966938_2967658_+	lipoyl(octanoyl) transferase LipB	NA	NA	NA	NA
WP_012596142.1\|2967605_2968814_-\|protease	trypsin-like serine protease	A0A1B1IT49	uncultured_Mediterranean_phage	4.2e-27	30.1
WP_012596143.1\|2969267_2970257_+	ribose-phosphate pyrophosphokinase	NA	NA	NA	NA
WP_012596144.1\|2970348_2970912_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_012596145.1\|2971074_2971257_-	hypothetical protein	NA	NA	NA	NA
WP_012596146.1\|2972526_2973519_-\|transposase	transposase	NA	NA	NA	NA
WP_157861305.1\|2973792_2975013_+	hypothetical protein	NA	NA	NA	NA
WP_012596147.1\|2975559_2976543_+	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_012596148.1\|2976631_2978044_+	protein translocase subunit SecD	NA	NA	NA	NA
WP_012596149.1\|2978160_2979093_+	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	4.7e-34	36.5
WP_012596150.1\|2979225_2980161_+\|tRNA	tRNA epoxyqueuosine(34) reductase QueG	NA	NA	NA	NA
WP_012596151.1\|2980228_2980888_+	HAD hydrolase-like protein	NA	NA	NA	NA
WP_012596152.1\|2980911_2981424_+	glutathione S-transferase	NA	NA	NA	NA
WP_012596153.1\|2981513_2982074_-	response regulator	NA	NA	NA	NA
WP_012596154.1\|2982379_2982955_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_4

3528364 : 3593333

Staphylococcus_phage(22.22%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041229853.1\|3528364_3529381_-\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_012596612.1\|3529753_3530317_-	DUF2808 domain-containing protein	NA	NA	NA	NA
WP_012596613.1\|3530528_3531800_+	lipid-A-disaccharide synthase	NA	NA	NA	NA
WP_012596614.1\|3531914_3532850_+	hypothetical protein	NA	NA	NA	NA
WP_012596615.1\|3533031_3533670_+	hypothetical protein	NA	NA	NA	NA
WP_012596616.1\|3533701_3534976_-	WcaI family glycosyltransferase	NA	NA	NA	NA
WP_012596617.1\|3535286_3535796_+	hypothetical protein	NA	NA	NA	NA
WP_012596618.1\|3535825_3536713_+	hypothetical protein	NA	NA	NA	NA
WP_012596619.1\|3536869_3537370_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_012596620.1\|3537469_3540001_-	glycogen/starch/alpha-glucan phosphorylase	Q8B3H5	Iris_mild_mosaic_virus	2.0e-15	44.8
WP_012596621.1\|3540414_3540966_-	DUF2854 domain-containing protein	NA	NA	NA	NA
WP_012596623.1\|3541369_3541966_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_012596624.1\|3542017_3542593_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_012596625.1\|3542773_3543823_-	S-methyl-5-thioribose-1-phosphate isomerase	NA	NA	NA	NA
WP_012596626.1\|3544317_3544785_+\|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_012593019.1\|3544982_3546137_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_012596627.1\|3546377_3546938_+\|transposase	transposase	NA	NA	NA	NA
WP_012596628.1\|3547001_3547247_-	hypothetical protein	NA	NA	NA	NA
WP_012596629.1\|3547360_3547489_-	photosystem I reaction center subunit IX	NA	NA	NA	NA
WP_012596630.1\|3547589_3548087_-	photosystem I reaction center protein PsaF subunit III	A0A0K0KWQ1	Prochlorococcus_phage	3.1e-16	48.9
WP_012596631.1\|3548237_3549284_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	7.0e-71	45.6
WP_012596632.1\|3549632_3550667_+	L-histidine N(alpha)-methyltransferase	NA	NA	NA	NA
WP_012596633.1\|3550754_3551006_-	hypothetical protein	NA	NA	NA	NA
WP_012596634.1\|3551340_3552270_+	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	1.0e-17	25.3
WP_012596635.1\|3552327_3554016_+	CHAT domain-containing protein	NA	NA	NA	NA
WP_012596636.1\|3554079_3554574_-	DUF4168 domain-containing protein	NA	NA	NA	NA
WP_012596637.1\|3554685_3555462_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.0e-14	25.4
WP_012596638.1\|3555669_3556440_+	hypothetical protein	NA	NA	NA	NA
WP_012596639.1\|3556542_3557634_+	4-hydroxyphenylpyruvate dioxygenase	NA	NA	NA	NA
WP_012596640.1\|3557802_3558159_+	hypothetical protein	NA	NA	NA	NA
WP_012596641.1\|3558221_3560195_+	glycogen debranching protein	NA	NA	NA	NA
WP_012596642.1\|3560221_3560797_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_012596643.1\|3560824_3563080_-	LPS biosynthesis protein	NA	NA	NA	NA
WP_012596644.1\|3563246_3563579_-	hypothetical protein	NA	NA	NA	NA
WP_012596645.1\|3563774_3564722_+	phospholipase	NA	NA	NA	NA
WP_012596646.1\|3564741_3566766_+	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	2.1e-119	36.9
WP_012596647.1\|3566814_3567825_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_012596648.1\|3567866_3568319_+	YbhB/YbcL family Raf kinase inhibitor-like protein	NA	NA	NA	NA
WP_012596650.1\|3569052_3570151_-	peptide chain release factor 2	B5LLF2	Mycobacterium_phage	1.7e-06	48.3
WP_012596651.1\|3570212_3570881_-	cyanoexosortase A system-associated protein	NA	NA	NA	NA
WP_012596652.1\|3570901_3571822_-	cyanoexosortase A	NA	NA	NA	NA
WP_012596653.1\|3571937_3572375_-	DUF1824 family protein	NA	NA	NA	NA
WP_012596654.1\|3572731_3573604_+\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_012596655.1\|3573625_3574081_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_012596657.1\|3574657_3576127_-	TldD/PmbA family protein	NA	NA	NA	NA
WP_012596658.1\|3576363_3577836_+	9,9'-di-cis-zeta-carotene desaturase	NA	NA	NA	NA
WP_012596659.1\|3577903_3578353_+	membrane protein	NA	NA	NA	NA
WP_012596660.1\|3578413_3579445_+	thiamine phosphate synthase	NA	NA	NA	NA
WP_012596661.1\|3579458_3579686_+	thiamine biosynthesis protein ThiS	NA	NA	NA	NA
WP_012596662.1\|3579715_3580378_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_012596663.1\|3580384_3580750_-	hypothetical protein	NA	NA	NA	NA
WP_012596664.1\|3580779_3583419_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	2.6e-05	30.2
WP_012596665.1\|3583654_3583921_+	hypothetical protein	NA	NA	NA	NA
WP_012596666.1\|3583945_3584443_+	DUF2335 domain-containing protein	NA	NA	NA	NA
WP_012596667.1\|3584457_3586128_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase RibB/GTP cyclohydrolase II RibA	A0A2H4PQS2	Staphylococcus_phage	2.9e-103	48.5
WP_012596668.1\|3586754_3586928_+	hypothetical protein	NA	NA	NA	NA
WP_012596668.1\|3587070_3587244_+	hypothetical protein	NA	NA	NA	NA
WP_012596669.1\|3587578_3590437_+	S-layer family protein	NA	NA	NA	NA
WP_041229859.1\|3590696_3592325_+	BamA/TamA family outer membrane protein	NA	NA	NA	NA
WP_012596671.1\|3592472_3593333_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	NA	NA	NA	NA

DBSCAN-SWA_5

4082435 : 4135234

Staphylococcus_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012597099.1\|4082435_4083047_-\|transposase	IS607 family transposase	A0A7Q0	Microcystis_virus	1.4e-50	49.2
WP_012597100.1\|4083264_4084254_+	glycosyltransferase	NA	NA	NA	NA
WP_012597101.1\|4084273_4084861_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_012597102.1\|4084918_4087390_-	phospholipid carrier-dependent glycosyltransferase	NA	NA	NA	NA
WP_012597103.1\|4087755_4088721_+	hydratase	NA	NA	NA	NA
WP_012597104.1\|4088889_4089477_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_012597105.1\|4089519_4090653_+	3-amino-5-hydroxybenzoic acid synthase	A0A2P1ELT3	Moumouvirus	1.7e-25	30.7
WP_041229683.1\|4090838_4091081_+	DUF4238 domain-containing protein	NA	NA	NA	NA
WP_012594856.1\|4091108_4091507_-\|transposase	IS200/IS605 family transposase	Q332K6	Clostridium_botulinum_C_phage	1.3e-33	49.2
WP_012594855.1\|4091551_4092760_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_012597107.1\|4093000_4093492_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_012597108.1\|4093478_4093688_+	hypothetical protein	NA	NA	NA	NA
WP_012597109.1\|4093907_4095512_-	TROVE domain-containing protein	G1JVR6	Mycobacterium_phage	3.6e-66	33.4
WP_012597110.1\|4095992_4096601_-	hypothetical protein	NA	NA	NA	NA
WP_012597111.1\|4096594_4097299_-	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_012597112.1\|4097690_4097906_+	hypothetical protein	NA	NA	NA	NA
WP_012597113.1\|4098185_4098503_+	DUF4258 domain-containing protein	NA	NA	NA	NA
WP_012597114.1\|4098530_4098773_+	YgiT-type zinc finger protein	NA	NA	NA	NA
WP_012597115.1\|4098821_4099043_-	hypothetical protein	NA	NA	NA	NA
WP_157861313.1\|4099029_4099176_-	hypothetical protein	NA	NA	NA	NA
WP_012597116.1\|4099178_4099997_-	hypothetical protein	NA	NA	NA	NA
WP_012597117.1\|4100093_4100342_-	hypothetical protein	NA	NA	NA	NA
WP_157861314.1\|4100859_4101798_+	hypothetical protein	NA	NA	NA	NA
WP_012597119.1\|4101828_4105467_-	pyruvate:ferredoxin (flavodoxin) oxidoreductase	NA	NA	NA	NA
WP_012597120.1\|4106327_4107758_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	2.2e-35	27.8
WP_083767409.1\|4107839_4108529_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_012593019.1\|4108663_4109818_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_083767410.1\|4110017_4110221_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_012597121.1\|4110490_4111066_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_012597122.1\|4111149_4111515_-	hypothetical protein	NA	NA	NA	NA
WP_012597123.1\|4111692_4112190_+	glutathione peroxidase	A0A0M5HSM9	Turkeypox_virus	3.6e-17	37.9
WP_012597125.1\|4112725_4113313_-	Uma2 family endonuclease	NA	NA	NA	NA
WP_012597126.1\|4113351_4113981_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_012597127.1\|4114227_4114938_+	DUF1997 domain-containing protein	NA	NA	NA	NA
WP_012597128.1\|4115496_4116579_+	ATP-dependent 6-phosphofructokinase	NA	NA	NA	NA
WP_012597129.1\|4116699_4117698_-	phosphoribulokinase	A0A2H4UUR3	Bodo_saltans_virus	1.6e-27	33.3
WP_012597130.1\|4118125_4119022_+	response regulator	NA	NA	NA	NA
WP_012597131.1\|4119014_4119293_+	KaiB 1	NA	NA	NA	NA
WP_012597132.1\|4119489_4121013_+	circadian clock protein KaiC	NA	NA	NA	NA
WP_012597133.1\|4121344_4123375_+	SAM-dependent DNA methyltransferase	A0A1W6JNK1	Staphylococcus_phage	7.6e-13	23.6
WP_012597134.1\|4123486_4123774_+	type II toxin-antitoxin system HigB family toxin	NA	NA	NA	NA
WP_012597135.1\|4123776_4124004_+	hypothetical protein	NA	NA	NA	NA
WP_012597136.1\|4124081_4124345_+	hypothetical protein	NA	NA	NA	NA
WP_012597137.1\|4124341_4124743_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_012597138.1\|4125144_4126506_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	2.8e-35	33.4
WP_012597139.1\|4126583_4126811_+	hypothetical protein	NA	NA	NA	NA
WP_012597140.1\|4126813_4127272_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_041229685.1\|4127293_4127554_+	hypothetical protein	NA	NA	NA	NA
WP_012597141.1\|4128364_4130650_+	pyruvate, water dikinase	A0A2I7RQW7	Vibrio_phage	5.9e-06	32.7
WP_012597142.1\|4130730_4131972_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A1L2BWN4	Bacteriophage	2.2e-119	56.1
WP_012597143.1\|4132388_4134275_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7IW18	Paramecium_bursaria_Chlorella_virus	4.1e-114	40.3
WP_012597144.1\|4134403_4135234_+\|transposase	heteromeric transposase endonuclease subunit TnsA	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_011721

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_011727

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_011726

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection