CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_012582	Vibrio cholerae O395 chromosome I, complete sequence	1 crisprs	cas8e,cse2gr11,cas6e,cas7,cas5,cas1,cas2,DEDDh,DinG,csa3,cas3,WYL,csx1,RT	0	10	5	0
NC_012583	Vibrio cholerae O395 chromosome II, complete sequence	0 crisprs	PD-DExK,csa3,cas3	0	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_012582_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012582_1

343449-345856

TypeI-E

I-B,III-A,III-B

Consensus_repeat	Method
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CRISPRCasFinder
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CRT

39 spacers

cas2,cas1,cas5,cas7,cas6e,cse2gr11,cas8e,cas3

The CRISPR arrays of NC_012582_1

>merge|NC_012582|1|343449-345856|CRISPRCasFinder,CRT
GTCTTCCCCACGCAGGTGGGGGTGTTTCCAAATGGCTCAATGCGCGATTGACTACGTTACTGTCTTCCCCACGCAGGTGGGGGTGTTTCCAATCAACGCACTAGACAACGCCCAAATGAACCGTCTTCCCCACGCAGGTGGGGGTGTTTCCAACGCTATGCCCGCTAAAATCAGTAAACAAGAGTCTTCCCCACGCAGGTGGGGGTGTTTCTATATTTCGCTCCCGTCTCGTCAACTAAAATCAGTCTTCCCCACGCAGGTGGGGGTGTTTCCTTCAAATAAGTAACCAGCCTCTGACGCTGTTAGTCTTCCCCACGCAGGTGGGGGTGTTTCCACCGCTAATCATGGTGGAACGAACGCCATCAAGTCTTCCCCACGCAGGTGGGGGTGTTTCTGATTTTGGAAGTAATGGGAACTGAGCGTTAAGGTCTTCCCCACGCAGGTGGGGGTGTTTCCCAAAAACCTACGCGGTTTTAAATGGATTCGACGTCTTCCCCACGCAGGTGGGGGTGTTTCTATCTTGGTTTTGCAGGTTGTTAATCTCAGCGTGTCTTCCCCACGCAGGTGGGGGTGTTTCTGATTGGTTCCAGTTTATGACAAGAACCAACACGTCTTCCCCACGCAGGTGGGGGTGTTTCTACATTGGCAAGACGTTTGTTTTTCGCTGTGTAGTCTTCCCCACGCAGGTGGGGGTGTTTCCGACTTTTGCATCATCGATGTACGGAACGCTAGGTCTTCCCCACGCAGGTGGGGGTGTTTCCACTGAGATTGCGTGTCGCCGACTTGCGCTTGCGTCTTCCCCACGCAGGTGGGGGTGTTTCTAGACTATCAATGTGCGCTTGCAAGTCTTTTAAGTCTTCCCCACGCAGGTGGGGGTGTTTCTTGATCGCTCTGAAATTGTGACTTGTTTTGTTAGTCTTCCCCACGCAGGTGGGGGTGTTTCTAGATCTTAATTGTTCGCGTTGAATGGGAAATTGTCTTCCCCACGCAGGTGGGGGTGTTTCCAGATTGTAGATAAGCAGGAGACTGCCCACCAGGTCTTCCCCACGCAGGTGGGGGTGTTTCCGGTTGATAAAACGCTGCGTAAGTTTTTCGAAGGTCTTCCCCACGCAGGTGGGGGTGTTTCTAAAACTTCATAGATTGTTGCCTCCATTGTTTCGTCTTCCCCACGCAGGTGGGGGTGTTTCTACGTCAACGGACAAACCAAAACCGAATGGAAGGTCTTCCCCACGCAGGTGGGGGTGTTTCTAAGTAACGCTGCTACTGCCCTGAGCTAGTACCGTCTTCCCCACGCAGGTGGGGGTGTTTCTACTGGCCGATGAGGTGGACCGCTACGGCTTCAGTCTTCCCCACGCAGGTGGGGGTGTTTCTCACCCAGCACATTACCACCCATGATCAGCGTTGTCTTCCCCACGCAGGTGGGGGTGTTTCCGAGTGGGTTTAGGTTGTAGGTTGCACATACGCGTCTTCCCCACGCAGGTGGGGGTGTTTCTTCGAAAAGCTATTAGGCGGCATAACCACAGTTGTCTTCCCCACGCAGGTGGGGGTGTTTCCAACAAACCAGCCACTTTGCATTTTGTAGCAGAGTCTTCCCCACGCAGGTGGGGGTGTTTCTGGAAGTTATTTATATTGGACCTGATTGCACGGGTCTTCCCCACGCAGGTGGGGGTGTTTCTACTTTGGGCCTTGTTTTATGTGCCAGTGCCCGGTCTTCCCCACGCAGGTGGGGGTGTTTCCCACTATTTCAATAATCGGCGTAGCTCCGACTGGTCTTCCCCACGCAGGTGGGGGTGTTTCCGTAATCTTCTTTGTCTGAGTAATCCAAAATACGTCTTCCCCACGCAGGTGGGGGTGTTTCTCATGGCAGCGATATTTGTTTTACCCTTCATACGTCTTCCCCACGCAGGTGGGGGTGTTTCCATCTGGAACGCACTCAAGCGGCAATCCGAAGTGTCTTCCCCACGCAGGTGGGGGTGTTTCCAGCAATGTGTTATCCAATGCGAAAGCGCCGTTGTCTTCCCCACGCAGGTGGGGGTGTTTCTATTTTGCGTATCACCGAAGCGCTGTAGGTTATGTCTTCCCCACGCAGGTGGGGGTGTTTCTACGTCCAGCATTACCGCCGCGCCGTGTCGAGTGTCTTCCCCACGCAGGTGGGGGTGTTTCTCCTCCCTGCTCATATGCCGTTAAAACTTTCTCGTCTTCCCCACGCAGGTGGGGGTGTTTCTCTGATGCGGCAAGCTCTTTCGCTAGCTCGATTGTCTTCCCCACGCAGGTGGGGGTGTTTCTACAACATCCATGCAAGCGGCAAAGAATACAAAGTCTTCCCCACGCAGGTGGGGTGTGTTTCCTCTTTAATCGAATTCCATAACGGTGACGTTAAGTCTTCCCCACGCAGGTTGGATTACAGA

>NC_012582|1|1|343449-345856|CRISPRCasFinder
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAAATGGCTCAATGCGCGATTGACTACGTTACT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAATCAACGCACTAGACAACGCCCAAATGAACC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAACGCTATGCCCGCTAAAATCAGTAAACAAGA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TATATTTCGCTCCCGTCTCGTCAACTAAAATCA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CTTCAAATAAGTAACCAGCCTCTGACGCTGTTA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CACCGCTAATCATGGTGGAACGAACGCCATCAA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TGATTTTGGAAGTAATGGGAACTGAGCGTTAAG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CCAAAAACCTACGCGGTTTTAAATGGATTCGAC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TATCTTGGTTTTGCAGGTTGTTAATCTCAGCGT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TGATTGGTTCCAGTTTATGACAAGAACCAACAC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACATTGGCAAGACGTTTGTTTTTCGCTGTGTA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CGACTTTTGCATCATCGATGTACGGAACGCTAG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CACTGAGATTGCGTGTCGCCGACTTGCGCTTGC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TAGACTATCAATGTGCGCTTGCAAGTCTTTTAA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TTGATCGCTCTGAAATTGTGACTTGTTTTGTTA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TAGATCTTAATTGTTCGCGTTGAATGGGAAATT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAGATTGTAGATAAGCAGGAGACTGCCCACCAG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CGGTTGATAAAACGCTGCGTAAGTTTTTCGAAG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TAAAACTTCATAGATTGTTGCCTCCATTGTTTC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACGTCAACGGACAAACCAAAACCGAATGGAAG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TAAGTAACGCTGCTACTGCCCTGAGCTAGTACC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACTGGCCGATGAGGTGGACCGCTACGGCTTCA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TCACCCAGCACATTACCACCCATGATCAGCGTT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CGAGTGGGTTTAGGTTGTAGGTTGCACATACGC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TTCGAAAAGCTATTAGGCGGCATAACCACAGTT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAACAAACCAGCCACTTTGCATTTTGTAGCAGA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TGGAAGTTATTTATATTGGACCTGATTGCACGG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACTTTGGGCCTTGTTTTATGTGCCAGTGCCCG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CCACTATTTCAATAATCGGCGTAGCTCCGACTG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CGTAATCTTCTTTGTCTGAGTAATCCAAAATAC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TCATGGCAGCGATATTTGTTTTACCCTTCATAC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CATCTGGAACGCACTCAAGCGGCAATCCGAAGT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAGCAATGTGTTATCCAATGCGAAAGCGCCGTT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TATTTTGCGTATCACCGAAGCGCTGTAGGTTAT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACGTCCAGCATTACCGCCGCGCCGTGTCGAGT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TCCTCCCTGCTCATATGCCGTTAAAACTTTCTC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TCTGATGCGGCAAGCTCTTTCGCTAGCTCGATT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACAACATCCATGCAAGCGGCAAAGAATACAAA
GTCTTCCCCACGCAGGTGGGGTGTGTTT	CCTCTTTAATCGAATTCCATAACGGTGACGTTAA
GTCTTCCCCACGCAGGTTGGATTACAGA

>NC_012582|1|1|343449-345856|CRT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAAATGGCTCAATGCGCGATTGACTACGTTACT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAATCAACGCACTAGACAACGCCCAAATGAACC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAACGCTATGCCCGCTAAAATCAGTAAACAAGA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TATATTTCGCTCCCGTCTCGTCAACTAAAATCA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CTTCAAATAAGTAACCAGCCTCTGACGCTGTTA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CACCGCTAATCATGGTGGAACGAACGCCATCAA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TGATTTTGGAAGTAATGGGAACTGAGCGTTAAG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CCAAAAACCTACGCGGTTTTAAATGGATTCGAC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TATCTTGGTTTTGCAGGTTGTTAATCTCAGCGT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TGATTGGTTCCAGTTTATGACAAGAACCAACAC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACATTGGCAAGACGTTTGTTTTTCGCTGTGTA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CGACTTTTGCATCATCGATGTACGGAACGCTAG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CACTGAGATTGCGTGTCGCCGACTTGCGCTTGC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TAGACTATCAATGTGCGCTTGCAAGTCTTTTAA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TTGATCGCTCTGAAATTGTGACTTGTTTTGTTA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TAGATCTTAATTGTTCGCGTTGAATGGGAAATT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAGATTGTAGATAAGCAGGAGACTGCCCACCAG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CGGTTGATAAAACGCTGCGTAAGTTTTTCGAAG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TAAAACTTCATAGATTGTTGCCTCCATTGTTTC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACGTCAACGGACAAACCAAAACCGAATGGAAG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TAAGTAACGCTGCTACTGCCCTGAGCTAGTACC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACTGGCCGATGAGGTGGACCGCTACGGCTTCA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TCACCCAGCACATTACCACCCATGATCAGCGTT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CGAGTGGGTTTAGGTTGTAGGTTGCACATACGC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TTCGAAAAGCTATTAGGCGGCATAACCACAGTT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAACAAACCAGCCACTTTGCATTTTGTAGCAGA
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TGGAAGTTATTTATATTGGACCTGATTGCACGG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACTTTGGGCCTTGTTTTATGTGCCAGTGCCCG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CCACTATTTCAATAATCGGCGTAGCTCCGACTG
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CGTAATCTTCTTTGTCTGAGTAATCCAAAATAC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TCATGGCAGCGATATTTGTTTTACCCTTCATAC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CATCTGGAACGCACTCAAGCGGCAATCCGAAGT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	CAGCAATGTGTTATCCAATGCGAAAGCGCCGTT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TATTTTGCGTATCACCGAAGCGCTGTAGGTTAT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACGTCCAGCATTACCGCCGCGCCGTGTCGAGT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TCCTCCCTGCTCATATGCCGTTAAAACTTTCTC
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TCTGATGCGGCAAGCTCTTTCGCTAGCTCGATT
GTCTTCCCCACGCAGGTGGGGGTGTTTC	TACAACATCCATGCAAGCGGCAAAGAATACAAA
GTCTTCCCCACGCAGGTGGGGTGTGTTT	CCTCTTTAATCGAATTCCATAACGGTGACGTTAA
GTCTTCCCCACGCAGGTTGGATTACAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_012582.1\|WP_000141836.1\|347651_347873_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225848
NC_012582.1\|WP_000369825.1\|339273_339834_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	cse2gr11	cd09731_cse2gr11_CAS-I-E	gnl\|CDD\|187862
NC_012582.1\|WP_001907124.1\|343114_343405_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|233610
NC_012582.1\|WP_000973003.1\|345968_346664_+\|hypothetical-protein	unknown	unknown	unknown
NC_012582.1\|WP_000125077.1\|347872_348106_-\|AlpA-family-phage-regulatory-protein	unknown	unknown	gnl\|CDD\|283558
NC_012582.1\|WP_001016934.1\|340495_341539_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	cas7	pfam09344_cas7_CAS-I-E	gnl\|CDD\|378153
NC_012582.1\|WP_000462885.1\|349316_349613_-\|DNA-binding-transcriptional-regulator-Fis	unknown	unknown	gnl\|CDD\|179020
NC_012582.1\|WP_001292113.1\|339826_340474_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	cas6e	pfam08798_cas6e_CAS-I-E:CAS-IV	gnl\|CDD\|187858
NC_012582.1\|WP_001202659.1\|346848_347499_-\|inovirus-type-Gp2-protein	unknown	unknown	gnl\|CDD\|371695
NC_012582.1\|WP_001911136.1\|349636_350605_-\|tRNA-dihydrouridine-synthase-DusB	unknown	unknown	gnl\|CDD\|182440
NC_012582.1\|WP_001145807.1\|350744_351632_-\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|283886
NC_012582.1\|WP_000354613.1\|353198_353660_-\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	unknown	unknown	gnl\|CDD\|235777
NC_012582.1\|WP_000517532.1\|332574_333810_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271182
NC_012582.1\|WP_000333273.1\|341542_342259_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|273842
NC_012582.1\|WP_001051767.1\|342261_343137_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
NC_012582.1\|WP_001912164.1\|348172_348574_-\|hypothetical-protein	unknown	unknown	unknown
NC_012582.1\|WP_000426542.1\|337736_339260_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	cas8e	pfam09481_cas8e_CAS-I-E	gnl\|CDD\|187860
NC_012582.1\|WP_001912175.1\|333815_334799_+\|Fic-family-protein	unknown	unknown	gnl\|CDD\|225718
NC_012582.1\|WP_001214918.1\|335121_337734_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|182031
NC_012582.1\|WP_000884888.1\|351840_353184_-\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	unknown	unknown	gnl\|CDD\|236307

Protein	Function_ID	Function_description	E-value
NC_012582.1\|WP_000141836.1\|347651_347873_-\|hypothetical-protein	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	1.1065e-06
NC_012582.1\|WP_000369825.1\|339273_339834_+\|type-I-E-CRISPR-associated-protein-Cse2/CasB	gnl\|CDD\|187862	cd09731, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	8.99349e-34
NC_012582.1\|WP_001907124.1\|343114_343405_+\|type-I-E-CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|233610	TIGR01873, CRISPR-associated_endoribonuclease_Cas2, CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model represents a minor branch of the Cas2 family of CRISPR-associated endonuclease, whereas most Cas2 proteins are modeled instead by TIGR01573. This form of Cas2 is characteristic for the Ecoli subtype of CRISPR/Cas locus.	1.85389e-29
NC_012582.1\|WP_000125077.1\|347872_348106_-\|AlpA-family-phage-regulatory-protein	gnl\|CDD\|283558	pfam05930, Phage_AlpA, Prophage CP4-57 regulatory protein (AlpA). This family consists of several short bacterial and phage proteins which are related to the E. coli protein AlpA. AlpA suppress two phenotypes of a delta lon protease mutant, overproduction of capsular polysaccharide and sensitivity to UV light. Several of the sequences in this family are thought to be DNA-binding proteins.	3.73556e-14
NC_012582.1\|WP_001016934.1\|340495_341539_+\|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC	gnl\|CDD\|378153	pfam09344, Cas_CT1975, CT1975-like protein. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum.	2.24652e-114
NC_012582.1\|WP_000462885.1\|349316_349613_-\|DNA-binding-transcriptional-regulator-Fis	gnl\|CDD\|179020	PRK00430, fis, DNA-binding transcriptional regulator Fis.	1.10625e-52
NC_012582.1\|WP_001292113.1\|339826_340474_+\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	gnl\|CDD\|187858	cd09727, Cas6_I-E, CRISPR/Cas system-associated RAMP superfamily protein Cas6e. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6e is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-E subtype; Homologous to Cas6 (RAMP superfamily protein); Possesses double RRM/ferredoxin fold; also known as Cse3 family.	5.56092e-61
NC_012582.1\|WP_001911136.1\|349636_350605_-\|tRNA-dihydrouridine-synthase-DusB	gnl\|CDD\|182440	PRK10415, PRK10415, tRNA-dihydrouridine synthase B; Provisional.	0
NC_012582.1\|WP_001145807.1\|350744_351632_-\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	1.54338e-152
NC_012582.1\|WP_000354613.1\|353198_353660_-\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	gnl\|CDD\|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	1.99542e-80
NC_012582.1\|WP_000517532.1\|332574_333810_+\|site-specific-integrase	gnl\|CDD\|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.68621e-46
NC_012582.1\|WP_000333273.1\|341542_342259_+\|type-I-E-CRISPR-associated-protein-Cas5/CasD	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	9.33191e-53
NC_012582.1\|WP_001051767.1\|342261_343137_+\|type-I-E-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	7.89487e-119
NC_012582.1\|WP_001214918.1\|335121_337734_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	2.97298e-81
NC_012582.1\|WP_001202659.1\|346848_347499_-\|inovirus-type-Gp2-protein	gnl\|CDD\|371695	pfam11726, Inovirus_Gp2, Inovirus Gp2. Isoform G2P plays an essential role in viral DNA replication; it binds to the origin of replication and cleaves the dsDNA replicative form I (RFI) and becomes covalently bound to it via phosphotyrosine bond, generating the dsDNA replicative form II (RFII).	2.47056e-09
NC_012582.1\|WP_001912175.1\|333815_334799_+\|Fic-family-protein	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	2.55051e-47
NC_012582.1\|WP_000426542.1\|337736_339260_+\|type-I-E-CRISPR-associated-protein-Cse1/CasA	gnl\|CDD\|187860	cd09729, Cse1_I-E, CRISPR/Cas system-associated protein Cse1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; subunit of the Cascade complex; signature gene for I-E subtype; also known as Cse1/CasA/YgcL family.	2.03603e-89
NC_012582.1\|WP_000884888.1\|351840_353184_-\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	gnl\|CDD\|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	0

>NC_012582.1|WP_001907124.1|343114_343405_+|type-I-E-CRISPR-associated-endoribonuclease-Cas2
MLVVLANDLPPAVRGRMKLWFVEPRANVFVSGVKDSVAVTVVDYLMQHCPAESGLMLFRSIPDPPGYEIRYKGEVRKPVIQLSGLQLIVETLILSK
>NC_012582.1|WP_001051767.1|342261_343137_+|type-I-E-CRISPR-associated-endonuclease-Cas1
MAKGERLFVKVTRESLPQVKDKYPFIYLERGRLEIDDSSVKWIDADANIVPIPVATINTLLLGPGTSVTHDAIKTATAANCSISWVGEDSLLFYAAGFLPTADTRNLKKQMLLAASEESALKVARMMFAKRFPDADLEDKTLKSMMGMEGNRVKALYQQKAEQYGVGWRGRQFTPGKFSLSDLTNQIMTASNAALYGILCSAIHSMGYSPHIGFIHSGSPLPFVYDMADLYKEHLCIDLAFSLTRDMAGHYDKHKVSDAFRKRVISMDLLQQVSSDINELMGGGNARRTSK
>NC_012582.1|WP_000333273.1|341542_342259_+|type-I-E-CRISPR-associated-protein-Cas5/CasD
MCEKNAYLLLWLEGPLQAWGHDSKFGVRNTLNFPTRSGILGLLCCARGAGGEQREWLEKMSPMAMEVLAFERSDAEGEPIMREATLRDFHMVGSGYDDADPWQNLLIPKTAQGKKPNGAGTKMTYRYYLQDALFAVILEIPADDKEALEDALQNPRWDLYLGRKNCVPTELIYQGVYHSTETARQRAQELAENKCRHLSYTIVEGEQEGGEVFTLNDVPVQFGVSKRYRDRRVTLLEH
>NC_012582.1|WP_001016934.1|340495_341539_+|type-I-E-CRISPR-associated-protein-Cas7/Cse4/CasC
MNHTLKNTRIEFHILQSFPVTCLNRDDVGAPKSAIVGGVSRARVSSQCWKRQVRLAMSEFGIQLGVRSKKVAALLQQHCLSLGASEDQANACGEVMAGFFADDTLLFISDSEAKAFAAYAQEKEFDAKSLKDKELVKVAKKVVNKTLDALDIALFGRMVAKAAEMNVEAAASFAHAISTHKVSNELEFFTAVDDHKSEEESGSAHMGTLEYNSATYYRYVSLDLGQLQQTLGDDADLSTALEAFVKALYVAVPNARQTTQSGACPWEYARVLVRKGQRLQASFEQPVRAAGEGYLLPSKKALQNWLEQREKLSGSLFAKQGDYEWGDDLDYSIDHLIADLQSHLMVR
>NC_012582.1|WP_001292113.1|339826_340474_+|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MSELFASALHLDRRAVKALKITDAYSLHRVVYSLFPDVRSPEEKGGHTQSGIVYADQGGDFHGRKVLVVSDRMPNASVDGVHGEVVSKTISEAFLHHQTYRFKVQVNPVRKDKQSGKRIAVKGRQDIAQWFIERAAKSWGFEVHPQHLQIDSIEVQQFNDKHGRKITLGKAHIQGQLRVTNEPQFHHSFKHGIGKGRAFGCGLLQIVPIIENPFA
>NC_012582.1|WP_000369825.1|339273_339834_+|type-I-E-CRISPR-associated-protein-Cse2/CasB
MDNNPVVTRDSAVAQTSKTGRFITYVIERIQKDKGFAARLKRADNQTTEYQSWELLASFDVDLEKEWERLPYCIVGAALAKAKPKSNGHLTLGQAIAACYDDGNQSEQAKARLRRLLACSSSTEVCRILRPLLTLIESKGVALNYHQLLEQLLWYHGKAQDSIRARWAQDFYRRSASTQAHEVNYE
>NC_012582.1|WP_000426542.1|337736_339260_+|type-I-E-CRISPR-associated-protein-Cse1/CasA
MENCFNLIDEPWIPVTNAGLVSLREIFLNNALRSLGGNPVQKIALTKLLLAIAQSAATPEDDEDWRRMGYLGMADKCLSYLDQWHNRFYLYGNMPFLQMPAIQSAEVKSFGVLSPEVSTGNTTVLTESQQEQAHSDADKALLLVVQMAFGLSGKKTDNSVVLSPGYQGKYNDKGKAASGKAGSAVGHMGLLHSFWLAESVVESLWLNLLTQEDIGDLPMYSILGTAPWELMPSGEADSVAEALKTSLMGRLVPLGKFCLLTDNGIHYSDGIAHPSYLEGKADPSASVDFSQKKLKALWVNPDKRPWRELTALLQFIESGKSIGYETPQLARTIRRVKYGVESFAIWSGGLRVSSNAGEQYASGTDDYVQSEFWLLSSELGDSFLAQLKQEMSELSALQKTLWGAVVRYFRQLSDIDKSSAGKAQPFVANQAERATHLFWQLCERQAQALLDACNDDIDAKIERQRLRKIFAGYALRVFDQVCPNDSTRQLDAWAQFRPNYHQYLNVE
>NC_012582.1|WP_001214918.1|335121_337734_+|CRISPR-associated-helicase/endonuclease-Cas3
MRGRNKRNTGKIEISAIDFERCPAKTWQQVKGVVIPGRNVPEHCQIVGEIAKVLIQRFPPAIQRILFPVGSELAAACHDIGKVSPTFVAKIFKACGIDTQTLPALANVNPSLESQWGGHAGVSQATAEEIMAPKYVAHILGQHHGFSPSGVDDKRGNAAVFGGESWFEERRKLVNHLKEVLNTEWPKFERAEQARVVAGLTSVADWIGSGSFFEDPTQAWKPNVIKALNCAGFITPSIIKDMSFTDIFDPAKRNMKPREAQIQFVNQVTGPGVYVLEAQMGMGKTEAALYAAYRLLAEAKATGIYFALPTQLTSNKIYDRFNSFLEQIIAAETPNRAMLLHSGAWLLKQADMGEEGSPGGAWFNHNKRGLLAPFAVGTIDQALMAVMNVKHGFVRAFGLAGKVVILDEVHSYDLYTGTILNELVAFLRQIGCTVIILSATLSPARRHSLLQQRTSSSEYPLITALHNDRDSPSEVAIPCVDGAKVELTHCSNDLQAIEEAINRAAMGQQVLWIENTVADAQQRYLDMASRGVGLGCEVGLLHSRFTPQDREKNEQHWVSLFGKAGWSQRRQCGRILIGTQVLEQSIDIDADFLITQFAPTDMLLQRIGRLWRHLDAPRATSARCECWLLAPNLEQALSSPSSAFGLSAMVYSPYVLCRSLEVWLGLSHLALPSSIRPLIDQTYCERDESAQWAFLLHQLKAGSRYKTGEKALQALAKITLAKAGKTLPEHKADTRYSDQDTYEVLLLRAIRTSEGHTYIRLLDNRELILPHARYQLSKAQWRELAVELHQSLVKVSPKNCPDKISKHQLEQLHLHHVFYLGNPEEDEALLRIALVSPVGELLTLDGRRASDKYQLEYRHDLGYRVIVQKE
>NC_012582.1|WP_001912175.1|333815_334799_+|Fic-family-protein
MSYQPPYTITNQILSLVAQISECLGRLSVNCASPRELKLRKVNRVRTIQGSLAIEGNELSQEQITALLNGKRVLAPKKQVQEALNAINVYQELNSWSSHREVDLLQAHEVLMIGLQSVIGRYRMDGVGVFKDGQVLHMAPPAERVPKLMSELFQWLANDNSHPLIRSCVFHYEFEFIHPFSDGNGRMGRLWQTLILSEWNPLFAHLPVESFIYENQQAYYDAINRSTLKADSEPFIAFMLQMILNALQETEATTPQDAPQVAPQVKQLLDVLEGEMLREEIQAMLGLKDRKSFRDRYLKPALEAGLIEMTLPDKPTSKVQRYRKRGV
>NC_012582.1|WP_000517532.1|332574_333810_+|site-specific-integrase
MGKLYDKHLKAVLNKSHLKVFTLTDGDGLGARVSLQGNVRWQFRYKINGASKRVDLGDYPDLSLLKAREEAQKCREWLAEGHDPKLQRSVIRQETLKPVSVQDALEYWLVEYAESNRANADKHRSQFQKHIYPYIGALPLAQTETHHWIECFDRVRKGIAGKQRPAPVAAGYVLQNAKQALRFCRVRRYATSRVLDDLTVNDVGKKQRKKDRVLTAQELSDLWNAVQTPNKFLPYYCHLVKFLVVFGARTQEVRLSKWKEWDFEALIWTVPKEHSKTDEKIIRPIPDELVPWLLQLKEDSDKETLILGEEKSPETVSQQGRFFWQRLGHEEAWTLHDIRRTLATRLNELGVAPYVVEQLLGHSLGGVMAIYNRSQYLPEKREALTMWLEHLDIMTNKTNNVTSIISSKRTA
>NC_012582.1|WP_000973003.1|345968_346664_+|hypothetical-protein
MMILLQGYLLGAALVACGLLWVMVRHLDKHDWQWDKGDIWFHFVFMVLFWPLMLFGWVKQGRPNWADWLKPTANRADYYREMERAYRELKTCGAYVSYKPKPEGICDNSYGEFIFPSALLEKQLIERLRQSPHLQGNDEGKLLAWVQSRDESLQEPVDVPPMWSRFSYLADDLIAHNIGLVRCSVCHDEIETGQLQEKSVNLCGRVERKYLCPNGHALLAFELMRFTYSSR
>NC_012582.1|WP_001202659.1|346848_347499_-|inovirus-type-Gp2-protein
MRARILLHPTKSKLALYRHGDQVYQIFHRATGVDQNILQSSFDLAKSWRNHYSKFCGVILQLHQNQPSDNNQQLSTFLIKLMQALQKHYNTPNIGYFWIREQSGRDKQHYHLAVFISGHCCQHSGTIDTLANTLWKQQDERNFSYQVKNRIYKVNRYGFDKEWPSLLTRLSYFAKNDTKSRSPSRNSYGRSQLLKTTTQAKTLKNAKVISSSDHFY
>NC_012582.1|WP_000141836.1|347651_347873_-|hypothetical-protein
MTFDLSRQCNKAAMPLHIISKKELANLLHVNERTIHRMVKDKRLPEPMRTVGGNNGGWLLTTILEWQKSQKGH
>NC_012582.1|WP_000125077.1|347872_348106_-|AlpA-family-phage-regulatory-protein
MTAIEKLTQPNQLSCDRFVREAERRRITAISRSQAWKLEKEGRFPPRIKLGSRSVVWRLSDLTQWLDKQAGQYSEEA
>NC_012582.1|WP_001912164.1|348172_348574_-|hypothetical-protein
MFNQSLDEATKKELTILIKQKWAGITSKKPHTNRALDVIIPIAKAFFSHQSSVIVAIGLFVERLVEHVSKMHPTPPALKPLLQRSERKLAEGLRAVLEGGSYCESKSGKGAEILVDQFIASKLIEFYPEPALA
>NC_012582.1|WP_000462885.1|349316_349613_-|DNA-binding-transcriptional-regulator-Fis
MFEQNLTSEALTVTTVTSQDQITQKPLRDSVKASLKNYLAQLNGQEVTELYELVLAEVEQPLLDTIMQYTRGNQTRAATMMGINRGTLRKKLKKYGMN
>NC_012582.1|WP_001911136.1|349636_350605_-|tRNA-dihydrouridine-synthase-DusB
MKIGNHQLKNNLIVAPMAGVTDRPFRELCLRYGAGMAVSEMMSCNPALWKTAKSQNRMVHEGESGIRSVQIAGSDPQLMAEAAQFSVENGAQIIDINMGCPAKKVNKKLAGSALLRYPDVIEDILKAVVNAVNVPVTLKTRTGWDTDNKNCLSIAQLAEDCGIQALALHGRTRACMYKGEAEYDSIKAVKAAVSIPVIANGDIDSPEKARYVLEYTGADALMIGRPAQGRPWIFQEIQHFLEHGTTMPELPISEVKDIMLGHVTALHQFYGEYLGPRIARKHVSWYLQEHEQASAFRRTFNAIETADQQLDALEGYFDNVAS
>NC_012582.1|WP_001145807.1|350744_351632_-|50S-ribosomal-protein-L11-methyltransferase
MPWIQIKLNATNDNAEAIGDMLMEETGAVSVTFLDAKDTPVFEPLPGETRLWGDTDVVALYEADMDTSLILQQIKASNMLAEGFAHKVEQVEDKDWEREWMDNFHPMQFGRRLWICPSWREVPDPQAVNVMLDPGLAFGTGTHPTTALCLEWLDNLDLTGKTVIDFGCGSGILAIAAIKLGAAKVIGIDIDPQALLASKDNAARNGVEDQIEVYLPKDQPEGLVADVVVANILAGPLRELSPTIKGLLKPGGQLAMSGILDTQAESVAEFYRDDLELDPIAEKSEWCRISGRKLG
>NC_012582.1|WP_000884888.1|351840_353184_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit
MLDKVVIANRGEIALRILRACKELGIKTVAVHSTADRDLKHVLLADESICIGPAKSIDSYLNIPRIISAAEVTGAVAIHPGYGFLSENADFAEQVERSGFIFVGPRAETIRLMGDKVSAINAMKKAGVPCVPGSDGPLDNDEAKNKAHAKRIGYPVIIKASGGGGGRGMRVVRNEAELTKSIQMTRAEAKAAFNNDMVYMEKFLENPRHVEVQVIADGQGNAIHLAERDCSMQRRHQKVVEEAPAPGITEEMRKFIGERCTRACIEIGYRGAGTFEFLYENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSFKQEDIKIRGHAVECRINAEDPERFLPCPGKIERFHAPGGMGVRWESHIYSGYTVPAHYDSMIGKLITYGENRDVAIARMRNALNEMIVEGIKTNIPLQQAIMADENFQKGGTNIHYLEKKLGIK
>NC_012582.1|WP_000354613.1|353198_353660_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein
MDIRKIKKLIELVEESGIAELEISEGEESVRISRYGQPAPAPQVHYAAAPAPVAAPAPVAQAAAVAEAPAAAKVPAGHKVLSPMVGTFYRSPSPDAKAFIEVGQSVSVGDTLCIVEAMKMMNQIEADKSGVVTAILVEDGQTVEFDQPLVVIE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_012582_1	1.1\|343477\|33\|NC_012582\|CRISPRCasFinder,CRT	343477-343509	33	KJ572844	Vibrio phage 24, complete genome	5421-5453	0	1.0
NC_012582_1	1.1\|343477\|33\|NC_012582\|CRISPRCasFinder,CRT	343477-343509	33	NC_019457	Vibrio phage CP-T1, complete genome	5421-5453	0	1.0
NC_012582_1	1.1\|343477\|33\|NC_012582\|CRISPRCasFinder,CRT	343477-343509	33	MN379460	Vibrio phage Rostov M3 clone NODE_1_length_31129_cov_194.645 genomic sequence	23999-24031	0	1.0
NC_012582_1	1.20\|344636\|33\|NC_012582\|CRISPRCasFinder,CRT	344636-344668	33	NC_024369	Vibrio phage X29, complete genome	3013-3045	0	1.0
NC_012582_1	1.20\|344636\|33\|NC_012582\|CRISPRCasFinder,CRT	344636-344668	33	MK575466	Vibrio phage Rostov 7, complete genome	24143-24175	0	1.0
NC_012582_1	1.20\|344636\|33\|NC_012582\|CRISPRCasFinder,CRT	344636-344668	33	KJ545483	Vibrio phage phi 2, complete genome	3013-3045	0	1.0
NC_012582_1	1.22\|344758\|33\|NC_012582\|CRISPRCasFinder,CRT	344758-344790	33	NC_024369	Vibrio phage X29, complete genome	1892-1924	0	1.0
NC_012582_1	1.23\|344819\|33\|NC_012582\|CRISPRCasFinder,CRT	344819-344851	33	NC_024369	Vibrio phage X29, complete genome	18078-18110	0	1.0
NC_012582_1	1.23\|344819\|33\|NC_012582\|CRISPRCasFinder,CRT	344819-344851	33	MK575466	Vibrio phage Rostov 7, complete genome	39293-39325	0	1.0
NC_012582_1	1.1\|343477\|33\|NC_012582\|CRISPRCasFinder,CRT	343477-343509	33	NC_019518	Vibrio phage vB_VchM-138, complete genome	4837-4869	1	0.97
NC_012582_1	1.22\|344758\|33\|NC_012582\|CRISPRCasFinder,CRT	344758-344790	33	MK575466	Vibrio phage Rostov 7, complete genome	23022-23054	1	0.97
NC_012582_1	1.22\|344758\|33\|NC_012582\|CRISPRCasFinder,CRT	344758-344790	33	KJ545483	Vibrio phage phi 2, complete genome	1892-1924	1	0.97
NC_012582_1	1.23\|344819\|33\|NC_012582\|CRISPRCasFinder,CRT	344819-344851	33	KJ545483	Vibrio phage phi 2, complete genome	18078-18110	1	0.97
NC_012582_1	1.32\|345368\|33\|NC_012582\|CRISPRCasFinder,CRT	345368-345400	33	MK575466	Vibrio phage Rostov 7, complete genome	18644-18676	1	0.97
NC_012582_1	1.18\|344514\|33\|NC_012582\|CRISPRCasFinder,CRT	344514-344546	33	MN694651	Marine virus AFVG_250M473, complete genome	6085-6117	7	0.788
NC_012582_1	1.22\|344758\|33\|NC_012582\|CRISPRCasFinder,CRT	344758-344790	33	NZ_CP019438	Thioclava nitratireducens strain 25B10_4 plasmid unnamed1, complete sequence	188623-188655	7	0.788
NC_012582_1	1.22\|344758\|33\|NC_012582\|CRISPRCasFinder,CRT	344758-344790	33	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1691230-1691262	7	0.788
NC_012582_1	1.22\|344758\|33\|NC_012582\|CRISPRCasFinder,CRT	344758-344790	33	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	441132-441164	7	0.788
NC_012582_1	1.12\|344148\|33\|NC_012582\|CRISPRCasFinder,CRT	344148-344180	33	MG945679	UNVERIFIED: Microviridae sp. isolate 961-1602, complete genome	3426-3458	8	0.758
NC_012582_1	1.37\|345673\|33\|NC_012582\|CRISPRCasFinder,CRT	345673-345705	33	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	154379-154411	8	0.758
NC_012582_1	1.9\|343965\|33\|NC_012582\|CRISPRCasFinder,CRT	343965-343997	33	LN846931	Carnobacterium maltaromaticum strain LMA28 megaplasmid, complete genome	14882-14914	9	0.727
NC_012582_1	1.20\|344636\|33\|NC_012582\|CRISPRCasFinder,CRT	344636-344668	33	MH616779	Microviridae sp. isolate ctfg604, complete genome	4923-4955	9	0.727
NC_012582_1	1.6\|343782\|33\|NC_012582\|CRISPRCasFinder,CRT	343782-343814	33	NZ_CP034296	Vibrio parahaemolyticus strain 20140829008-1 plasmid pVPGD2014-1, complete sequence	89684-89716	10	0.697
NC_012582_1	1.6\|343782\|33\|NC_012582\|CRISPRCasFinder,CRT	343782-343814	33	NZ_CP034291	Vibrio parahaemolyticus strain 20140722001-1 plasmid pVPCZ2014-1, complete sequence	13026-13058	10	0.697
NC_012582_1	1.18\|344514\|33\|NC_012582\|CRISPRCasFinder,CRT	344514-344546	33	NZ_CP007449	Yersinia enterocolitica LC20 plasmid plasmid1_80K, complete sequence	74163-74195	10	0.697

1. spacer 1.1|343477|33|NC_012582|CRISPRCasFinder,CRT matches to KJ572844 (Vibrio phage 24, complete genome) position: , mismatch: 0, identity: 1.0

caaatggctcaatgcgcgattgactacgttact	CRISPR spacer
caaatggctcaatgcgcgattgactacgttact	Protospacer
*********************************

2. spacer 1.1|343477|33|NC_012582|CRISPRCasFinder,CRT matches to NC_019457 (Vibrio phage CP-T1, complete genome) position: , mismatch: 0, identity: 1.0

caaatggctcaatgcgcgattgactacgttact	CRISPR spacer
caaatggctcaatgcgcgattgactacgttact	Protospacer
*********************************

3. spacer 1.1|343477|33|NC_012582|CRISPRCasFinder,CRT matches to MN379460 (Vibrio phage Rostov M3 clone NODE_1_length_31129_cov_194.645 genomic sequence) position: , mismatch: 0, identity: 1.0

caaatggctcaatgcgcgattgactacgttact	CRISPR spacer
caaatggctcaatgcgcgattgactacgttact	Protospacer
*********************************

4. spacer 1.20|344636|33|NC_012582|CRISPRCasFinder,CRT matches to NC_024369 (Vibrio phage X29, complete genome) position: , mismatch: 0, identity: 1.0

tacgtcaacggacaaaccaaaaccgaatggaag	CRISPR spacer
tacgtcaacggacaaaccaaaaccgaatggaag	Protospacer
*********************************

5. spacer 1.20|344636|33|NC_012582|CRISPRCasFinder,CRT matches to MK575466 (Vibrio phage Rostov 7, complete genome) position: , mismatch: 0, identity: 1.0

tacgtcaacggacaaaccaaaaccgaatggaag	CRISPR spacer
tacgtcaacggacaaaccaaaaccgaatggaag	Protospacer
*********************************

6. spacer 1.20|344636|33|NC_012582|CRISPRCasFinder,CRT matches to KJ545483 (Vibrio phage phi 2, complete genome) position: , mismatch: 0, identity: 1.0

tacgtcaacggacaaaccaaaaccgaatggaag	CRISPR spacer
tacgtcaacggacaaaccaaaaccgaatggaag	Protospacer
*********************************

7. spacer 1.22|344758|33|NC_012582|CRISPRCasFinder,CRT matches to NC_024369 (Vibrio phage X29, complete genome) position: , mismatch: 0, identity: 1.0

tactggccgatgaggtggaccgctacggcttca	CRISPR spacer
tactggccgatgaggtggaccgctacggcttca	Protospacer
*********************************

8. spacer 1.23|344819|33|NC_012582|CRISPRCasFinder,CRT matches to NC_024369 (Vibrio phage X29, complete genome) position: , mismatch: 0, identity: 1.0

tcacccagcacattaccacccatgatcagcgtt	CRISPR spacer
tcacccagcacattaccacccatgatcagcgtt	Protospacer
*********************************

9. spacer 1.23|344819|33|NC_012582|CRISPRCasFinder,CRT matches to MK575466 (Vibrio phage Rostov 7, complete genome) position: , mismatch: 0, identity: 1.0

tcacccagcacattaccacccatgatcagcgtt	CRISPR spacer
tcacccagcacattaccacccatgatcagcgtt	Protospacer
*********************************

10. spacer 1.1|343477|33|NC_012582|CRISPRCasFinder,CRT matches to NC_019518 (Vibrio phage vB_VchM-138, complete genome) position: , mismatch: 1, identity: 0.97

caaatggctcaatgcgcgattgactacgttact	CRISPR spacer
caaatggttcaatgcgcgattgactacgttact	Protospacer
*******.*************************

11. spacer 1.22|344758|33|NC_012582|CRISPRCasFinder,CRT matches to MK575466 (Vibrio phage Rostov 7, complete genome) position: , mismatch: 1, identity: 0.97

tactggccgatgaggtggaccgctacggcttca	CRISPR spacer
tactggccgatgaggtggaccgctacggcttta	Protospacer
*******************************.*

12. spacer 1.22|344758|33|NC_012582|CRISPRCasFinder,CRT matches to KJ545483 (Vibrio phage phi 2, complete genome) position: , mismatch: 1, identity: 0.97

tactggccgatgaggtggaccgctacggcttca	CRISPR spacer
tgctggccgatgaggtggaccgctacggcttca	Protospacer
*.*******************************

13. spacer 1.23|344819|33|NC_012582|CRISPRCasFinder,CRT matches to KJ545483 (Vibrio phage phi 2, complete genome) position: , mismatch: 1, identity: 0.97

tcacccagcacattaccacccatgatcagcgtt	CRISPR spacer
ttacccagcacattaccacccatgatcagcgtt	Protospacer
*.*******************************

14. spacer 1.32|345368|33|NC_012582|CRISPRCasFinder,CRT matches to MK575466 (Vibrio phage Rostov 7, complete genome) position: , mismatch: 1, identity: 0.97

catctggaacgcactcaagcggcaatccgaagt	CRISPR spacer
catctggaacgtactcaagcggcaatccgaagt	Protospacer
***********.*********************

15. spacer 1.18|344514|33|NC_012582|CRISPRCasFinder,CRT matches to MN694651 (Marine virus AFVG_250M473, complete genome) position: , mismatch: 7, identity: 0.788

cggttgataaaacgctgcgtaagtttttcgaag----	CRISPR spacer
tggttgataaaactcagcgtaagttt----aagttga	Protospacer
.************ * **********    ***

16. spacer 1.22|344758|33|NC_012582|CRISPRCasFinder,CRT matches to NZ_CP019438 (Thioclava nitratireducens strain 25B10_4 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.788

tactggccgatgaggtggaccgctacggcttca	CRISPR spacer
gcctggccgatgagctggaccgctacggtccct	Protospacer
  ************ *************...*

17. spacer 1.22|344758|33|NC_012582|CRISPRCasFinder,CRT matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.788

-tactggccgatgaggtggaccgctacggcttca	CRISPR spacer
ccgccggct-atgcggtggaccgcgacggcttca	Protospacer
 ..*.***. *** ********** *********

18. spacer 1.22|344758|33|NC_012582|CRISPRCasFinder,CRT matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 7, identity: 0.788

-tactggccgatgaggtggaccgctacggcttca	CRISPR spacer
ccgccggct-atgcggtggaccgcgacggcttca	Protospacer
 ..*.***. *** ********** *********

19. spacer 1.12|344148|33|NC_012582|CRISPRCasFinder,CRT matches to MG945679 (UNVERIFIED: Microviridae sp. isolate 961-1602, complete genome) position: , mismatch: 8, identity: 0.758

cgacttttgcatcatcgatgtacggaacgctag	CRISPR spacer
cgacttttgcatcatcgccgtacggcttttaag	Protospacer
***************** .******  . . **

20. spacer 1.37|345673|33|NC_012582|CRISPRCasFinder,CRT matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 8, identity: 0.758

tctgatgc----ggcaagctctttcgctagctcgatt	CRISPR spacer
----atactattagcgagctctttcgcttgctcgatt	Protospacer
    **.*    .**.************ ********

21. spacer 1.9|343965|33|NC_012582|CRISPRCasFinder,CRT matches to LN846931 (Carnobacterium maltaromaticum strain LMA28 megaplasmid, complete genome) position: , mismatch: 9, identity: 0.727

tatcttggttttgcaggttgttaatctcagcgt	CRISPR spacer
cttcttggtttggcaggttgttcatccaacaat	Protospacer
. ********* ********** ***. *  .*

22. spacer 1.20|344636|33|NC_012582|CRISPRCasFinder,CRT matches to MH616779 (Microviridae sp. isolate ctfg604, complete genome) position: , mismatch: 9, identity: 0.727

tacgtcaacggacaaaccaaaaccgaatggaag	CRISPR spacer
aaaccaaacggacaaactaaaatcgaatggtaa	Protospacer
 *  . ***********.****.******* *.

23. spacer 1.6|343782|33|NC_012582|CRISPRCasFinder,CRT matches to NZ_CP034296 (Vibrio parahaemolyticus strain 20140829008-1 plasmid pVPGD2014-1, complete sequence) position: , mismatch: 10, identity: 0.697

caccgctaatcatggtggaacgaacgccatcaa	CRISPR spacer
caccgctaatcatggtggcaggaatgagtgtgc	Protospacer
****************** * ***.*    ..

24. spacer 1.6|343782|33|NC_012582|CRISPRCasFinder,CRT matches to NZ_CP034291 (Vibrio parahaemolyticus strain 20140722001-1 plasmid pVPCZ2014-1, complete sequence) position: , mismatch: 10, identity: 0.697

caccgctaatcatggtggaacgaacgccatcaa	CRISPR spacer
caccgctaatcatggtggcaggaatgagtgtgc	Protospacer
****************** * ***.*    ..

25. spacer 1.18|344514|33|NC_012582|CRISPRCasFinder,CRT matches to NZ_CP007449 (Yersinia enterocolitica LC20 plasmid plasmid1_80K, complete sequence) position: , mismatch: 10, identity: 0.697

cggttgataaaacgctgcgtaagtttttcgaag	CRISPR spacer
tcacgaacaaaacgatgcgtgagtttttcgaat	Protospacer
. .. .*.****** *****.***********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

584553 : 591777

uncultured_Mediterranean_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000698379.1\|584553_585306_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	8.0e-69	53.3
WP_000002982.1\|585298_585925_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.0e-36	52.1
WP_000177568.1\|585924_586860_+	murein hydrolase activator NlpD	D7RWE0	Brochothrix_phage	7.8e-05	34.7
WP_000116738.1\|586933_587941_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.0e-35	34.2
WP_001894770.1\|588033_590622_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	2.2e-33	23.0
WP_001279365.1\|590889_591777_-	cysteine synthase CysM	A0A1X9I5K7	Streptococcus_phage	4.1e-56	41.1

DBSCAN-SWA_2

823331 : 830524

Faustovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000775253.1\|823331_824546_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	1.1e-32	30.5
WP_000331703.1\|824582_824966_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	5.4e-53	78.2
WP_000301571.1\|825026_825350_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	3.0e-25	50.5
WP_001105747.1\|825398_825914_+	co-chaperone HscB	NA	NA	NA	NA
WP_001196560.1\|825937_827788_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	5.3e-106	41.1
WP_001124187.1\|827801_828140_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_000872176.1\|828188_828383_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_000107236.1\|828602_829892_+	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	4.9e-34	34.0
WP_001162850.1\|830095_830524_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.0e-20	38.4

DBSCAN-SWA_3

1208313 : 1331004

152

Vibrio_phage(84.38%)

transposase,protease,tail,tRNA,plate,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000821682.1\|1208313_1209177_+\|protease	protease HtpX	NA	NA	NA	NA
WP_000383061.1\|1209395_1209815_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_000127634.1\|1209811_1210537_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_000684176.1\|1210550_1211828_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_001145047.1\|1211827_1212637_+	DUF1365 domain-containing protein	NA	NA	NA	NA
WP_000935148.1\|1212626_1213868_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	4.2e-46	33.6
WP_001229555.1\|1213870_1214410_+	DUF2878 domain-containing protein	NA	NA	NA	NA
WP_000881186.1\|1214372_1214909_+	chalcone isomerase family protein	NA	NA	NA	NA
WP_001234232.1\|1214905_1215433_+	DUF3833 domain-containing protein	NA	NA	NA	NA
WP_000423489.1\|1215523_1216894_-	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	6.7e-114	47.5
WP_001262240.1\|1216951_1217569_-	high frequency lysogenization protein HflD	NA	NA	NA	NA
WP_000109998.1\|1217591_1218707_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000671609.1\|1218970_1220275_+	inosine/guanosine kinase	NA	NA	NA	NA
WP_001285966.1\|1220562_1221300_-	transcriptional regulator	A0A2I7S9A5	Vibrio_phage	4.3e-83	60.7
WP_000373567.1\|1221452_1221677_+	helix-turn-helix domain-containing protein	M1PVU4	Vibrio_phage	2.3e-16	61.9
WP_000270200.1\|1221688_1223692_+\|transposase	Mu transposase C-terminal domain-containing protein	A0A2I7S9A8	Vibrio_phage	4.2e-274	69.8
WP_000800334.1\|1223718_1224663_+	AAA family ATPase	M4M9P4	Vibrio_phage	1.1e-126	73.7
WP_000157297.1\|1224670_1224895_+	hypothetical protein	NA	NA	NA	NA
WP_000065387.1\|1224904_1225345_+	hypothetical protein	NA	NA	NA	NA
WP_001032751.1\|1225354_1225720_+	hypothetical protein	M4MB90	Vibrio_phage	6.9e-26	60.6
WP_001096736.1\|1225694_1225889_+	hypothetical protein	NA	NA	NA	NA
WP_001192102.1\|1225875_1226490_+	DUF3164 family protein	M4MHH7	Vibrio_phage	2.0e-86	79.6
WP_000512066.1\|1226499_1226772_+	hypothetical protein	A0A2I7S9G2	Vibrio_phage	1.7e-21	62.4
WP_000551394.1\|1226764_1227007_+	hypothetical protein	M4MCS5	Vibrio_phage	9.3e-19	60.8
WP_000414667.1\|1226990_1227188_+	hypothetical protein	NA	NA	NA	NA
WP_001292533.1\|1227184_1227655_+	hypothetical protein	M4MHH2	Vibrio_phage	2.2e-48	62.2
WP_000762331.1\|1227651_1228182_+	hypothetical protein	A0A0M3LPP6	Mannheimia_phage	2.2e-28	42.9
WP_000466684.1\|1228261_1228495_+	hypothetical protein	M4M9N5	Vibrio_phage	8.3e-25	67.5
WP_000581642.1\|1228512_1228698_+	DUF551 domain-containing protein	NA	NA	NA	NA
WP_000040558.1\|1228708_1229287_+	regulatory protein GemA	A0A2I7S9B8	Vibrio_phage	8.6e-55	59.3
WP_000158209.1\|1229273_1229522_+	hypothetical protein	NA	NA	NA	NA
WP_001029054.1\|1229600_1230017_+	positive regulator of late transcription	M4MHG9	Vibrio_phage	1.8e-30	50.0
WP_000493681.1\|1230101_1230650_+	N-acetylmuramidase	A0A2I7S9B9	Vibrio_phage	1.9e-72	72.7
WP_000828643.1\|1230649_1230940_+	hypothetical protein	NA	NA	NA	NA
WP_001121000.1\|1230915_1231512_+	hypothetical protein	M4MB79	Vibrio_phage	7.3e-49	58.6
WP_001281318.1\|1231508_1231739_+	TraR/DksA C4-type zinc finger protein	M4MHG5	Vibrio_phage	1.1e-18	63.2
WP_000362982.1\|1231738_1232038_+	DUF2730 family protein	M1Q558	Vibrio_phage	2.9e-30	71.0
WP_000008606.1\|1232046_1232337_+	hypothetical protein	A0A2I7S9D8	Vibrio_phage	3.9e-40	82.3
WP_001195536.1\|1232348_1232930_+	DUF3486 family protein	M4MCR3	Vibrio_phage	4.6e-64	69.5
WP_001105346.1\|1232930_1234496_+	hypothetical protein	M4MHG0	Vibrio_phage	1.9e-229	77.6
WP_000027036.1\|1234492_1236052_+	DUF935 domain-containing protein	M4M9P3	Vibrio_phage	4.2e-229	75.9
WP_001125593.1\|1236044_1236818_+	hypothetical protein	M1PVV7	Vibrio_phage	2.9e-114	75.1
WP_000246045.1\|1236829_1237078_+	hypothetical protein	NA	NA	NA	NA
WP_000638752.1\|1237074_1237587_+	hypothetical protein	A0A0F6N5P8	Escherichia_phage	4.1e-32	45.6
WP_000638761.1\|1237583_1238219_+	hypothetical protein	A0A1V0E8A2	Vibrio_phage	1.7e-40	47.3
WP_001249578.1\|1238218_1238503_+	hypothetical protein	NA	NA	NA	NA
WP_001218332.1\|1239793_1240693_+\|head	Mu-like prophage major head subunit gpT family protein	M4MB71	Vibrio_phage	5.5e-149	83.1
WP_000004757.1\|1240759_1241335_+	hypothetical protein	M4M9M3	Vibrio_phage	4.0e-20	54.5
WP_001029276.1\|1241340_1241775_+	DUF1320 domain-containing protein	A0A2I7S9E9	Vibrio_phage	9.6e-67	88.2
WP_000513476.1\|1241774_1242317_+	phage virion morphogenesis protein	A0A2I7S9D7	Vibrio_phage	4.3e-72	73.7
WP_000100986.1\|1242313_1242913_+	hypothetical protein	M4MHF0	Vibrio_phage	2.4e-68	60.7
WP_000437436.1\|1242926_1243127_+	DUF2635 domain-containing protein	A0A2I7S9K4	Vibrio_phage	2.6e-06	43.5
WP_001173614.1\|1243129_1244614_+\|tail	phage tail sheath subtilisin-like domain-containing protein	M1Q565	Vibrio_phage	6.2e-206	71.7
WP_000024431.1\|1244628_1244982_+\|tail	phage tail tube protein	A0A2I7S9D5	Vibrio_phage	1.1e-44	71.8
WP_000996595.1\|1244981_1245326_+\|tail	phage tail assembly protein	M4MB64	Vibrio_phage	2.4e-44	80.5
WP_000068600.1\|1245451_1247203_+	hypothetical protein	M4MHE6	Vibrio_phage	3.6e-189	62.8
WP_000863378.1\|1247214_1248534_+	DNA circularization N-terminal domain-containing protein	A0A2I7S9E8	Vibrio_phage	6.6e-167	68.0
WP_001286434.1\|1248526_1249603_+	hypothetical protein	M4M9L5	Vibrio_phage	1.8e-159	75.6
WP_044019770.1\|1249632_1250214_+\|plate	phage baseplate assembly protein V	M4MCP6	Vibrio_phage	5.4e-73	73.2
WP_000095017.1\|1250216_1250666_+	phage GP46 family protein	M4MB61	Vibrio_phage	1.5e-54	73.6
WP_001147108.1\|1250655_1251723_+\|plate	baseplate J/gp47 family protein	A0A2I7S9E5	Vibrio_phage	9.4e-148	72.1
WP_000510158.1\|1251707_1252295_+	DUF2313 domain-containing protein	A0A2I7S9L6	Vibrio_phage	1.4e-92	79.0
WP_000549338.1\|1252294_1253533_+	hypothetical protein	H9C145	Vibrio_phage	2.6e-181	83.0
WP_001065601.1\|1253532_1254072_+	hypothetical protein	H9C146	Vibrio_phage	2.3e-25	50.4
WP_001290200.1\|1254188_1254596_-	H-NS histone family protein	NA	NA	NA	NA
WP_001048829.1\|1255289_1256891_+	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_001194704.1\|1257299_1258196_+	ATP phosphoribosyltransferase	NA	NA	NA	NA
WP_001261315.1\|1258200_1259496_+	histidinol dehydrogenase	NA	NA	NA	NA
WP_000412889.1\|1259499_1260540_+	histidinol-phosphate transaminase	NA	NA	NA	NA
WP_000043567.1\|1260591_1261665_+	bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB	NA	NA	NA	NA
WP_000193249.1\|1261664_1262276_+	imidazole glycerol phosphate synthase subunit HisH	NA	NA	NA	NA
WP_000586511.1\|1262318_1263056_+	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	A0A2H4UVM0	Bodo_saltans_virus	9.5e-06	22.6
WP_000880146.1\|1263037_1263811_+	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_001067502.1\|1263807_1264440_+	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE	NA	NA	NA	NA
WP_000098720.1\|1264640_1265366_-	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_001142855.1\|1265673_1267899_+	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_000190603.1\|1267997_1268219_-	cold shock domain-containing protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	9.7e-15	58.2
WP_000041728.1\|1268691_1269012_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.3e-12	39.5
WP_000932415.1\|1269050_1271321_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	6.6e-167	42.8
WP_001018084.1\|1271389_1273066_-	aspartate:alanine antiporter	NA	NA	NA	NA
WP_000498418.1\|1273267_1273531_-	GrxA family glutaredoxin	A0A2I7SAE2	Vibrio_phage	2.9e-26	70.5
WP_000486145.1\|1273839_1275087_+	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_001093848.1\|1275177_1276032_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_000253201.1\|1276339_1277986_-	putative pyridoxal-dependent aspartate 1-decarboxylase	S4W1T5	Pandoravirus	2.3e-20	27.3
WP_000826868.1\|1278095_1278605_-	hypothetical protein	NA	NA	NA	NA
WP_000948497.1\|1278793_1279699_-	lysine exporter LysO family protein	NA	NA	NA	NA
WP_000019000.1\|1279719_1280640_-	HDOD domain-containing protein	A0A1C3NFB0	Phage_NCTB	1.3e-07	21.9
WP_001005366.1\|1281017_1281605_+	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_001232643.1\|1281700_1282249_-	hypothetical protein	NA	NA	NA	NA
WP_001031964.1\|1282439_1282937_-	response regulator	NA	NA	NA	NA
WP_001082992.1\|1282933_1284889_-	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_000835928.1\|1285111_1286377_+	YdgA family protein	NA	NA	NA	NA
WP_000400868.1\|1286498_1287593_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	3.9e-88	47.0
WP_000506955.1\|1287673_1288663_-	alpha-L-glutamate ligase-like protein	NA	NA	NA	NA
WP_000202050.1\|1288662_1290171_-	inactive transglutaminase family protein	NA	NA	NA	NA
WP_000476327.1\|1290179_1290917_-\|protease	ATP-dependent zinc protease	NA	NA	NA	NA
WP_000481534.1\|1291036_1292008_-\|tRNA	tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB	NA	NA	NA	NA
WP_001068374.1\|1292119_1292848_-	carboxy-S-adenosyl-L-methionine synthase CmoA	NA	NA	NA	NA
WP_001880947.1\|1292985_1293855_-	DUF72 domain-containing protein	NA	NA	NA	NA
WP_001256500.1\|1294146_1295922_+\|tRNA	aspartate--tRNA ligase	A0A1V0SAC0	Catovirus	8.4e-08	22.8
WP_001880948.1\|1296018_1296597_+	thymidine kinase	A0A1Z1LZ42	Serratia_phage	1.2e-56	56.0
WP_001065601.1\|1297494_1298034_-	hypothetical protein	H9C146	Vibrio_phage	2.3e-25	50.4
WP_000549338.1\|1298033_1299272_-	hypothetical protein	H9C145	Vibrio_phage	2.6e-181	83.0
WP_000510158.1\|1299271_1299859_-	DUF2313 domain-containing protein	A0A2I7S9L6	Vibrio_phage	1.4e-92	79.0
WP_001147108.1\|1299843_1300911_-\|plate	baseplate J/gp47 family protein	A0A2I7S9E5	Vibrio_phage	9.4e-148	72.1
WP_000095017.1\|1300900_1301350_-	phage GP46 family protein	M4MB61	Vibrio_phage	1.5e-54	73.6
WP_044019770.1\|1301352_1301934_-\|plate	phage baseplate assembly protein V	M4MCP6	Vibrio_phage	5.4e-73	73.2
WP_001286434.1\|1301963_1303040_-	hypothetical protein	M4M9L5	Vibrio_phage	1.8e-159	75.6
WP_000863378.1\|1303032_1304352_-	DNA circularization N-terminal domain-containing protein	A0A2I7S9E8	Vibrio_phage	6.6e-167	68.0
WP_000068600.1\|1304363_1306115_-	hypothetical protein	M4MHE6	Vibrio_phage	3.6e-189	62.8
WP_000996595.1\|1306240_1306585_-\|tail	phage tail assembly protein	M4MB64	Vibrio_phage	2.4e-44	80.5
WP_000024431.1\|1306584_1306938_-\|tail	phage tail tube protein	A0A2I7S9D5	Vibrio_phage	1.1e-44	71.8
WP_001173614.1\|1306952_1308437_-\|tail	phage tail sheath subtilisin-like domain-containing protein	M1Q565	Vibrio_phage	6.2e-206	71.7
WP_000437436.1\|1308439_1308640_-	DUF2635 domain-containing protein	A0A2I7S9K4	Vibrio_phage	2.6e-06	43.5
WP_000100986.1\|1308653_1309253_-	hypothetical protein	M4MHF0	Vibrio_phage	2.4e-68	60.7
WP_000513476.1\|1309249_1309792_-	phage virion morphogenesis protein	A0A2I7S9D7	Vibrio_phage	4.3e-72	73.7
WP_001029276.1\|1309791_1310226_-	DUF1320 domain-containing protein	A0A2I7S9E9	Vibrio_phage	9.6e-67	88.2
WP_000004757.1\|1310231_1310807_-	hypothetical protein	M4M9M3	Vibrio_phage	4.0e-20	54.5
WP_001218332.1\|1310873_1311773_-\|head	Mu-like prophage major head subunit gpT family protein	M4MB71	Vibrio_phage	5.5e-149	83.1
WP_001249578.1\|1313063_1313348_-	hypothetical protein	NA	NA	NA	NA
WP_000638761.1\|1313347_1313983_-	hypothetical protein	A0A1V0E8A2	Vibrio_phage	1.7e-40	47.3
WP_000638752.1\|1313979_1314492_-	hypothetical protein	A0A0F6N5P8	Escherichia_phage	4.1e-32	45.6
WP_000246045.1\|1314488_1314737_-	hypothetical protein	NA	NA	NA	NA
WP_001125593.1\|1314748_1315522_-	hypothetical protein	M1PVV7	Vibrio_phage	2.9e-114	75.1
WP_000027036.1\|1315514_1317074_-	DUF935 domain-containing protein	M4M9P3	Vibrio_phage	4.2e-229	75.9
WP_001105346.1\|1317070_1318636_-	hypothetical protein	M4MHG0	Vibrio_phage	1.9e-229	77.6
WP_001195536.1\|1318636_1319218_-	DUF3486 family protein	M4MCR3	Vibrio_phage	4.6e-64	69.5
WP_000008606.1\|1319229_1319520_-	hypothetical protein	A0A2I7S9D8	Vibrio_phage	3.9e-40	82.3
WP_000362982.1\|1319528_1319828_-	DUF2730 family protein	M1Q558	Vibrio_phage	2.9e-30	71.0
WP_001281318.1\|1319827_1320058_-	TraR/DksA C4-type zinc finger protein	M4MHG5	Vibrio_phage	1.1e-18	63.2
WP_001121000.1\|1320054_1320651_-	hypothetical protein	M4MB79	Vibrio_phage	7.3e-49	58.6
WP_000828643.1\|1320626_1320917_-	hypothetical protein	NA	NA	NA	NA
WP_000493681.1\|1320916_1321465_-	N-acetylmuramidase	A0A2I7S9B9	Vibrio_phage	1.9e-72	72.7
WP_001029054.1\|1321549_1321966_-	positive regulator of late transcription	M4MHG9	Vibrio_phage	1.8e-30	50.0
WP_000158209.1\|1322044_1322293_-	hypothetical protein	NA	NA	NA	NA
WP_000040558.1\|1322279_1322858_-	regulatory protein GemA	A0A2I7S9B8	Vibrio_phage	8.6e-55	59.3
WP_000581642.1\|1322868_1323054_-	DUF551 domain-containing protein	NA	NA	NA	NA
WP_000466684.1\|1323071_1323305_-	hypothetical protein	M4M9N5	Vibrio_phage	8.3e-25	67.5
WP_000762331.1\|1323384_1323915_-	hypothetical protein	A0A0M3LPP6	Mannheimia_phage	2.2e-28	42.9
WP_001292533.1\|1323911_1324382_-	hypothetical protein	M4MHH2	Vibrio_phage	2.2e-48	62.2
WP_000414667.1\|1324378_1324576_-	hypothetical protein	NA	NA	NA	NA
WP_000551394.1\|1324559_1324802_-	hypothetical protein	M4MCS5	Vibrio_phage	9.3e-19	60.8
WP_000512066.1\|1324794_1325067_-	hypothetical protein	A0A2I7S9G2	Vibrio_phage	1.7e-21	62.4
WP_001192102.1\|1325076_1325691_-	DUF3164 family protein	M4MHH7	Vibrio_phage	2.0e-86	79.6
WP_001096736.1\|1325677_1325872_-	hypothetical protein	NA	NA	NA	NA
WP_001032751.1\|1325846_1326212_-	hypothetical protein	M4MB90	Vibrio_phage	6.9e-26	60.6
WP_000065387.1\|1326221_1326662_-	hypothetical protein	NA	NA	NA	NA
WP_000157297.1\|1326671_1326896_-	hypothetical protein	NA	NA	NA	NA
WP_000800334.1\|1326903_1327848_-	AAA family ATPase	M4M9P4	Vibrio_phage	1.1e-126	73.7
WP_000270200.1\|1327874_1329878_-\|transposase	Mu transposase C-terminal domain-containing protein	A0A2I7S9A8	Vibrio_phage	4.2e-274	69.8
WP_000373567.1\|1329889_1330114_-	helix-turn-helix domain-containing protein	M1PVU4	Vibrio_phage	2.3e-16	61.9
WP_001285966.1\|1330266_1331004_+	transcriptional regulator	A0A2I7S9A5	Vibrio_phage	4.3e-83	60.7

DBSCAN-SWA_4

1633058 : 1658796

Vibrio_phage(58.82%)

coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001097338.1\|1633058_1635218_-	type I secretion system permease/ATPase	W8CYL7	Bacillus_phage	1.6e-48	28.6
WP_001092347.1\|1635220_1636582_-	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
WP_001911009.1\|1637844_1645737_+	alpha/beta fold hydrolase	B3Y8K3	Vibrio_virus	4.9e-07	100.0
WP_000593519.1\|1646194_1646569_-	cholera enterotoxin binding subunit CtxB	A0A142I6Y1	Vibrio_phage	5.9e-65	100.0
WP_001881225.1\|1646565_1647342_-	cholera enterotoxin catalytic subunit CtxA	A0A142I6Y0	Vibrio_phage	1.3e-151	100.0
WP_000021609.1\|1647461_1648661_-	zonula occludens toxin ZOT	A0A023W604	Vibrio_virus	8.4e-238	99.2
WP_011929321.1\|1648657_1648951_-	accessory cholera enterotoxin	A0A0F6YNQ7	Vibrio_phage	1.2e-44	97.9
WP_001268539.1\|1648947_1650135_-\|coat	minor coat protein pIII	Q8LTP2	Vibrio_virus	1.9e-181	92.4
WP_000493023.1\|1650241_1650490_-	colonization factor	A0A0F6WBH0	Vibrio_phage	8.8e-33	100.0
WP_000842207.1\|1650625_1650982_-	hypothetical protein	A0A0N9HJ67	Vibrio_phage	9.7e-65	100.0
WP_000743997.1\|1650983_1652063_-	replication initiation factor domain-containing protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000492997.1\|1652194_1652530_+	helix-turn-helix transcriptional regulator	A0A0N9HJE7	Vibrio_phage	4.7e-53	100.0
WP_000842207.1\|1652771_1653128_-	hypothetical protein	A0A0N9HJ67	Vibrio_phage	9.7e-65	100.0
WP_000743997.1\|1653129_1654209_-	replication initiation factor domain-containing protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000492997.1\|1654340_1654676_+	helix-turn-helix transcriptional regulator	A0A0N9HJE7	Vibrio_phage	4.7e-53	100.0
WP_000170634.1\|1655294_1655879_-	DNA-binding protein	E3U9I9	Vibrio_phage	6.4e-114	100.0
WP_001161489.1\|1655871_1656039_-	hypothetical protein	E3U9J0	Vibrio_phage	2.3e-13	100.0
WP_001052672.1\|1656116_1656809_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000512956.1\|1656938_1657208_-	hypothetical protein	NA	NA	NA	NA
WP_001881266.1\|1657227_1658796_-	replication protein	A7BJY2	Enterobacteria_phage	2.7e-58	32.3

DBSCAN-SWA_5

2507540 : 2514157

Staphylococcus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000864130.1\|2507540_2508011_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	6.8e-34	48.7
WP_001122865.1\|2508275_2509385_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-64	39.8
WP_000493874.1\|2509425_2510079_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-31	38.2
WP_001131982.1\|2510083_2511187_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.3e-43	33.1
WP_000543544.1\|2511212_2511662_-	transcriptional regulator NrdR	NA	NA	NA	NA
WP_000366574.1\|2511761_2513012_-	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.0e-100	49.5
WP_000210573.1\|2513023_2514157_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.4e-64	40.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_012583

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

211084 : 281606

Vibrio_phage(81.48%)

transposase,capsid,terminase,tail,plate,head,portal,protease,integrase

attL 205160:205175|attR 218778:218793

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
205160:205175	attL	NA	NA	NA	NA
WP_000779169.1\|211084_211927_-	potassium channel family protein	A0A1B0Y2S3	Lactobacillus_phage	7.5e-07	44.0
WP_000251270.1\|211992_212541_-	outer membrane beta-barrel protein	NA	NA	NA	NA
WP_001217709.1\|213198_214242_+	GMP reductase	A0A0N9Q9A5	Chrysochromulina_ericina_virus	1.8e-98	53.6
WP_000116330.1\|214374_215406_-\|integrase	tyrosine-type recombinase/integrase	A0A1S6L016	Salmonella_phage	1.1e-97	52.9
WP_000985033.1\|215405_215819_-	hypothetical protein	U3PDE6	Vibrio_phage	8.9e-70	100.0
WP_000132153.1\|215818_216724_-	BRCT domain-containing protein	U3PB51	Vibrio_phage	1.3e-161	100.0
WP_011929346.1\|216749_217397_-	phage repressor protein CI	A0A166YHA0	Vibrio_phage	8.7e-88	77.0
WP_000959026.1\|217545_217758_+	hypothetical protein	U3PFJ1	Vibrio_phage	6.4e-32	100.0
WP_000253094.1\|217868_218408_+	phage regulatory CII family protein	U3PIJ8	Vibrio_phage	1.0e-94	98.9
WP_001272765.1\|218420_218855_+	hypothetical protein	U3PDF0	Vibrio_phage	2.8e-74	100.0
218778:218793	attR	NA	NA	NA	NA
WP_001031153.1\|218936_219470_+	hypothetical protein	U3PB56	Vibrio_phage	1.6e-84	98.3
WP_000997543.1\|219466_219877_+	hypothetical protein	U3PCE8	Vibrio_phage	1.0e-70	93.4
WP_001198814.1\|220126_220354_+	hypothetical protein	U3PIK2	Vibrio_phage	3.2e-37	100.0
WP_000099608.1\|220350_220968_+	DNA methyltransferase	U3PDF3	Vibrio_phage	1.2e-118	100.0
WP_000629095.1\|220964_221075_+	hypothetical protein	NA	NA	NA	NA
WP_000613059.1\|221071_221656_+	hypothetical protein	U3PB60	Vibrio_phage	1.1e-102	97.4
WP_001094898.1\|221652_224214_+	replication endonuclease	A0A166YHE2	Vibrio_phage	0.0e+00	95.5
WP_000756239.1\|224223_224760_+	DUF262 domain-containing protein	U3PFK3	Vibrio_phage	4.1e-99	100.0
WP_001140410.1\|224833_225172_-	helix-turn-helix transcriptional regulator	Q8HA49	Vibrio_phage	2.1e-53	100.0
WP_001292394.1\|225409_225655_+	hypothetical protein	U3PDF9	Vibrio_phage	4.5e-37	98.8
WP_001263191.1\|225655_225907_-	ogr/Delta-like zinc finger family protein	U3PB63	Vibrio_phage	1.9e-43	100.0
WP_000448633.1\|225977_226463_-	type II toxin-antitoxin system YhaV family toxin	Q8HA46	Vibrio_phage	6.9e-90	99.4
WP_000521064.1\|226466_226661_-	hypothetical protein	Q8HA45	Vibrio_phage	5.1e-28	100.0
WP_000204987.1\|227116_227794_+	Bro-N domain-containing protein	Q8HA44	Vibrio_phage	1.8e-128	100.0
WP_002034218.1\|227790_228813_-\|portal	phage portal protein	U3PFK6	Vibrio_phage	3.2e-185	91.7
WP_000331804.1\|228809_230627_-\|terminase	terminase ATPase subunit family protein	U3PIL1	Vibrio_phage	0.0e+00	99.2
WP_001127096.1\|230800_231700_+\|capsid	GPO family capsid scaffolding protein	A0A160DHM4	Vibrio_phage	1.2e-122	99.7
WP_000078357.1\|231736_232759_+\|capsid	phage major capsid protein, P2 family	A0A160DHH1	Vibrio_phage	1.7e-186	96.4
WP_000059162.1\|232762_233479_+\|terminase	terminase endonuclease subunit	U3PCG2	Vibrio_phage	1.3e-124	93.3
WP_000494022.1\|233585_234047_+\|head	head completion/stabilization protein	U3PFL1	Vibrio_phage	5.8e-78	99.3
WP_000107425.1\|234043_234526_+\|tail	phage tail protein	U3PIL4	Vibrio_phage	4.4e-52	63.2
WP_000628619.1\|234522_235179_+	hypothetical protein	R9TPZ7	Vibrio_phage	9.6e-18	33.3
WP_000312536.1\|235180_236290_+	DUF2586 family protein	U3PB71	Vibrio_phage	1.0e-205	98.4
WP_000063627.1\|236289_236748_+	DUF2597 family protein	U3PCG7	Vibrio_phage	1.3e-82	100.0
WP_000382491.1\|236762_236972_+	TraR/DksA family transcriptional regulator	U3PFL5	Vibrio_phage	2.0e-33	100.0
WP_001077689.1\|236968_237196_+	hypothetical protein	U3PIL8	Vibrio_phage	2.1e-36	100.0
WP_000705018.1\|237182_237770_+	lysozyme	U3PDH1	Vibrio_phage	8.2e-77	67.7
WP_001113534.1\|237744_238086_+	hypothetical protein	U3PB75	Vibrio_phage	3.2e-49	95.6
WP_002034229.1\|238135_238297_+	hypothetical protein	A0A166YHN7	Vibrio_phage	1.4e-23	96.2
WP_000165783.1\|238293_238575_+	hypothetical protein	A0A160DHS7	Vibrio_phage	5.3e-34	76.3
WP_000343646.1\|238771_240589_+\|tail	phage tail tape measure protein	U3PFL8	Vibrio_phage	1.5e-249	75.9
WP_001113003.1\|240578_240911_+	DUF2590 family protein	U3PIM1	Vibrio_phage	1.7e-55	100.0
WP_000044511.1\|240907_242107_+\|plate	baseplate J/gp47 family protein	U3PDH5	Vibrio_phage	1.9e-221	99.2
WP_000005872.1\|242103_242763_+	hypothetical protein	U3PB79	Vibrio_phage	3.1e-125	99.5
WP_000083762.1\|242759_244598_+\|tail	phage tail protein	Q8HA52	Vibrio_phage	0.0e+00	100.0
WP_000369862.1\|244597_245122_+	hypothetical protein	Q8HA51	Vibrio_phage	9.1e-96	100.0
WP_000267790.1\|245124_246018_+	hypothetical protein	U3PIM3	Vibrio_phage	6.0e-156	97.0
WP_000457680.1\|246005_246479_+	hypothetical protein	U3PDI0	Vibrio_phage	1.1e-76	99.4
WP_000779004.1\|246475_248107_+	hypothetical protein	A0A160DHT6	Vibrio_phage	4.3e-309	97.4
WP_001883155.1\|249448_250600_+	DNA cytosine methyltransferase	A0A1P8CX13	Bacillus_phage	2.9e-25	26.3
WP_000762954.1\|250723_252640_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_000606740.1\|252632_253757_+	DUF3696 domain-containing protein	NA	NA	NA	NA
WP_000849738.1\|253753_254632_+	hypothetical protein	NA	NA	NA	NA
WP_000503164.1\|254699_255137_-\|transposase	IS200/IS605-like element IS1004 family transposase	Q331U4	Clostridium_botulinum_C_phage	1.9e-22	40.8
WP_079993097.1\|255268_255493_-	HNH endonuclease	NA	NA	NA	NA
WP_000507087.1\|255641_256997_-	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	1.7e-48	36.4
WP_000967516.1\|257186_258515_-	anaerobic C4-dicarboxylate transporter	NA	NA	NA	NA
WP_000400328.1\|258765_259596_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.4e-58	47.4
WP_000717524.1\|259698_260226_+	nicotinate-nicotinamide nucleotide adenylyltransferase	NA	NA	NA	NA
WP_000362857.1\|260492_262034_+	DUF3369 domain-containing protein	NA	NA	NA	NA
WP_000796029.1\|262091_264038_-	hypothetical protein	W8CYF6	Bacillus_phage	7.3e-05	23.3
WP_001267880.1\|264287_265262_+	hypothetical protein	NA	NA	NA	NA
WP_001046719.1\|265339_266920_-	Na+/H+ antiporter NhaC family protein	NA	NA	NA	NA
WP_001276502.1\|267323_268529_-	multidrug efflux MFS transporter EmrD	NA	NA	NA	NA
WP_000949610.1\|268781_269048_+	hypothetical protein	NA	NA	NA	NA
WP_000178906.1\|269038_270118_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	3.8e-19	32.8
WP_000746867.1\|270238_271495_-	thermolabile hemolysin	NA	NA	NA	NA
WP_000586206.1\|274977_276624_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	3.3e-22	29.4
WP_001033424.1\|276971_277910_+	triacylglycerol lipase	NA	NA	NA	NA
WP_000717572.1\|277919_278774_+	lipase secretion chaperone	NA	NA	NA	NA
WP_000848953.1\|278849_281606_-\|protease	M6 family metalloprotease PrtV	NA	NA	NA	NA

DBSCAN-SWA_2

696422 : 702758

Vibrio_phage(66.67%)

coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000593519.1\|696422_696797_-	cholera enterotoxin binding subunit CtxB	A0A142I6Y1	Vibrio_phage	5.9e-65	100.0
WP_001881225.1\|696793_697570_-	cholera enterotoxin catalytic subunit CtxA	A0A142I6Y0	Vibrio_phage	1.3e-151	100.0
WP_000021609.1\|697689_698889_-	zonula occludens toxin ZOT	A0A023W604	Vibrio_virus	8.4e-238	99.2
WP_011929321.1\|698885_699179_-	accessory cholera enterotoxin	A0A0F6YNQ7	Vibrio_phage	1.2e-44	97.9
WP_001268539.1\|699175_700363_-\|coat	minor coat protein pIII	Q8LTP2	Vibrio_virus	1.9e-181	92.4
WP_000493023.1\|700469_700718_-	colonization factor	A0A0F6WBH0	Vibrio_phage	8.8e-33	100.0
WP_000842207.1\|700853_701210_-	hypothetical protein	A0A0N9HJ67	Vibrio_phage	9.7e-65	100.0
WP_000743997.1\|701211_702291_-	replication initiation factor domain-containing protein	U5TQR3	Satellite_phage	2.2e-213	100.0
WP_000492997.1\|702422_702758_+	helix-turn-helix transcriptional regulator	A0A0N9HJE7	Vibrio_phage	4.7e-53	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_012582

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_012583

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection