CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_011899	Halothermothrix orenii H 168, complete sequence	1 crisprs	csa3,DEDDh,DinG,cas3,csx20,csx1,csm6,cmr6gr7,cmr5gr11,cmr4gr7,cmr3gr5,cas10,cmr1gr7,cas6,cas4,cas2,cas1,cas5,cas7b,cas8b1,WYL	0	2	1	0

1. NC_011899

CRISPR-Cas detection and classification

Crispr_ID: NC_011899_1

• CRISPR_ID: NC_011899_1
• CRISPR_location: 1621711-1623280
• CRISPR_type: TypeIII
• Repeat_type: NA
• Spacer_info: 21 spacers
• Cas_protein_info: cmr1gr7,cas10,cmr3gr5,cmr4gr7,cmr5gr11,cmr6gr7,csm6,csx1,csx20,cas6,cas4,cas2,cas1,cas3,cas5,cas7b,cas8b1,WYL

Consensus repeat of NC_011899_1

Consensus_repeat	Method
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	PILER-CR
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CRISPRCasFinder
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CRT

spacers of NC_011899_1

>1.1|1621748|37|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CCTCCTCAAAATAGGTTATTGCCATATATACCCCTGT
>1.2|1621822|37|NC_011899|PILER-CR,CRISPRCasFinder,CRT
TTATATGTTGCAACACTTACATCTCCTTTATTTCAAG
>1.3|1621896|36|NC_011899|PILER-CR,CRISPRCasFinder,CRT
TCAACCTGAAAATCCTTTAGAAAGTCCCTTTTAATC
>1.4|1621969|37|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CGCCTACCGGACAATTTACCAGGAAAAAAGACCCGCT
>1.5|1622043|35|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CCGATTTATACCGTTTTTCGATATCAGGGTAGTTA
>1.6|1622115|38|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CAACCTTTTTCATGACCCCAATTTAACTATTGGGCATT
>1.7|1622190|37|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CTAGATTAACTATTGAAAACCACCTTATATCTTCAGA
>1.8|1622264|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CATTCGGTAGCTTCTGAATCTTCCCATTTGAGGG
>1.9|1622335|36|NC_011899|PILER-CR,CRISPRCasFinder,CRT
TGGAGTGGTGGCCGAATTGGCGATGGCGCCGGACTG
>1.10|1622408|35|NC_011899|PILER-CR,CRISPRCasFinder,CRT
TGATTACCTAAAGTCAAATCGTAACTAGCTGGTTG
>1.11|1622480|37|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CAATAAGGGGTGATTGTTTTGGCCCACTTACAAAAAA
>1.12|1622554|36|NC_011899|PILER-CR,CRISPRCasFinder,CRT
TATTTGTGATTTGTTTGATAGTCATCAACCTATCAT
>1.13|1622627|36|NC_011899|PILER-CR,CRISPRCasFinder,CRT
TCTGAAAGCAGGTACTTATGTTGAGCCTATTCGTGG
>1.14|1622700|36|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CTGGAAAGAATGTAAAACTAGGGGAAAAAGCTATCA
>1.15|1622773|35|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CTAACACTAGCATTATAAGGCGGATCAGTCAACAC
>1.16|1622845|37|NC_011899|PILER-CR,CRISPRCasFinder,CRT
TTAGCATAGAACTCCTCCAATCTCGATAACCAGTCTC
>1.17|1622919|36|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CTAAAACCGGCAGAAGAAAAAGAAAATATAAAAATA
>1.18|1622992|38|NC_011899|PILER-CR,CRISPRCasFinder,CRT
GCATAGCACAATTATTTTAGAAGGGTGATGTTTTTGAG
>1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT
TAATATTAACTTTCCAATTATCAGGTTTGCTTAA
>1.20|1623138|35|NC_011899|PILER-CR,CRISPRCasFinder,CRT
TTCTGTTGAAGCATCTGTTATGTTTGGCGATTCAT
>1.21|1623210|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT
CCAATGATCTTTGCCAAATCCTCTTGAGAATAAT

CRISPR arrays and Neighbor proteins around NC_011899_1

CRISPR arrays

The CRISPR arrays of NC_011899_1

>merge|NC_011899|1|1621711-1623280|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCCTCCTCAAAATAGGTTATTGCCATATATACCCCTGTGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCTTATATGTTGCAACACTTACATCTCCTTTATTTCAAGGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCTCAACCTGAAAATCCTTTAGAAAGTCCCTTTTAATCGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCGCCTACCGGACAATTTACCAGGAAAAAAGACCCGCTGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCCGATTTATACCGTTTTTCGATATCAGGGTAGTTAGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCAACCTTTTTCATGACCCCAATTTAACTATTGGGCATTGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCTAGATTAACTATTGAAAACCACCTTATATCTTCAGAGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCATTCGGTAGCTTCTGAATCTTCCCATTTGAGGGGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCTGGAGTGGTGGCCGAATTGGCGATGGCGCCGGACTGGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCTGATTACCTAAAGTCAAATCGTAACTAGCTGGTTGGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCAATAAGGGGTGATTGTTTTGGCCCACTTACAAAAAAGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCTATTTGTGATTTGTTTGATAGTCATCAACCTATCATGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCTCTGAAAGCAGGTACTTATGTTGAGCCTATTCGTGGGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCTGGAAAGAATGTAAAACTAGGGGAAAAAGCTATCAGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCTAACACTAGCATTATAAGGCGGATCAGTCAACACGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCTTAGCATAGAACTCCTCCAATCTCGATAACCAGTCTCGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCTAAAACCGGCAGAAGAAAAAGAAAATATAAAAATAGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCGCATAGCACAATTATTTTAGAAGGGTGATGTTTTTGAGGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATTTAATATTAACTTTCCAATTATCAGGTTTGCTTAAGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCTTCTGTTGAAGCATCTGTTATGTTTGGCGATTCATGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATCCCAATGATCTTTGCCAAATCCTCTTGAGAATAATGTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC

>NC_011899|1|1|1621711-1623280|PILER-CR
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CCTCCTCAAAATAGGTTATTGCCATATATACCCCTGT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TTATATGTTGCAACACTTACATCTCCTTTATTTCAAG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TCAACCTGAAAATCCTTTAGAAAGTCCCTTTTAATC
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CGCCTACCGGACAATTTACCAGGAAAAAAGACCCGCT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CCGATTTATACCGTTTTTCGATATCAGGGTAGTTA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CAACCTTTTTCATGACCCCAATTTAACTATTGGGCATT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTAGATTAACTATTGAAAACCACCTTATATCTTCAGA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CATTCGGTAGCTTCTGAATCTTCCCATTTGAGGG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TGGAGTGGTGGCCGAATTGGCGATGGCGCCGGACTG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TGATTACCTAAAGTCAAATCGTAACTAGCTGGTTG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CAATAAGGGGTGATTGTTTTGGCCCACTTACAAAAAA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TATTTGTGATTTGTTTGATAGTCATCAACCTATCAT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TCTGAAAGCAGGTACTTATGTTGAGCCTATTCGTGG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTGGAAAGAATGTAAAACTAGGGGAAAAAGCTATCA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTAACACTAGCATTATAAGGCGGATCAGTCAACAC
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TTAGCATAGAACTCCTCCAATCTCGATAACCAGTCTC
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTAAAACCGGCAGAAGAAAAAGAAAATATAAAAATA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	GCATAGCACAATTATTTTAGAAGGGTGATGTTTTTGAG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATT	TAATATTAACTTTCCAATTATCAGGTTTGCTTAA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TTCTGTTGAAGCATCTGTTATGTTTGGCGATTCAT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CCAATGATCTTTGCCAAATCCTCTTGAGAATAAT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC

>NC_011899|1|1|1621711-1623280|CRISPRCasFinder
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CCTCCTCAAAATAGGTTATTGCCATATATACCCCTGT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TTATATGTTGCAACACTTACATCTCCTTTATTTCAAG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TCAACCTGAAAATCCTTTAGAAAGTCCCTTTTAATC
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CGCCTACCGGACAATTTACCAGGAAAAAAGACCCGCT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CCGATTTATACCGTTTTTCGATATCAGGGTAGTTA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CAACCTTTTTCATGACCCCAATTTAACTATTGGGCATT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTAGATTAACTATTGAAAACCACCTTATATCTTCAGA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CATTCGGTAGCTTCTGAATCTTCCCATTTGAGGG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TGGAGTGGTGGCCGAATTGGCGATGGCGCCGGACTG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TGATTACCTAAAGTCAAATCGTAACTAGCTGGTTG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CAATAAGGGGTGATTGTTTTGGCCCACTTACAAAAAA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TATTTGTGATTTGTTTGATAGTCATCAACCTATCAT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TCTGAAAGCAGGTACTTATGTTGAGCCTATTCGTGG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTGGAAAGAATGTAAAACTAGGGGAAAAAGCTATCA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTAACACTAGCATTATAAGGCGGATCAGTCAACAC
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TTAGCATAGAACTCCTCCAATCTCGATAACCAGTCTC
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTAAAACCGGCAGAAGAAAAAGAAAATATAAAAATA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	GCATAGCACAATTATTTTAGAAGGGTGATGTTTTTGAG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATT	TAATATTAACTTTCCAATTATCAGGTTTGCTTAA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TTCTGTTGAAGCATCTGTTATGTTTGGCGATTCAT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CCAATGATCTTTGCCAAATCCTCTTGAGAATAAT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC

>NC_011899|1|1|1621711-1623280|CRT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CCTCCTCAAAATAGGTTATTGCCATATATACCCCTGT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TTATATGTTGCAACACTTACATCTCCTTTATTTCAAG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TCAACCTGAAAATCCTTTAGAAAGTCCCTTTTAATC
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CGCCTACCGGACAATTTACCAGGAAAAAAGACCCGCT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CCGATTTATACCGTTTTTCGATATCAGGGTAGTTA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CAACCTTTTTCATGACCCCAATTTAACTATTGGGCATT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTAGATTAACTATTGAAAACCACCTTATATCTTCAGA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CATTCGGTAGCTTCTGAATCTTCCCATTTGAGGG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TGGAGTGGTGGCCGAATTGGCGATGGCGCCGGACTG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TGATTACCTAAAGTCAAATCGTAACTAGCTGGTTG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CAATAAGGGGTGATTGTTTTGGCCCACTTACAAAAAA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TATTTGTGATTTGTTTGATAGTCATCAACCTATCAT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TCTGAAAGCAGGTACTTATGTTGAGCCTATTCGTGG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTGGAAAGAATGTAAAACTAGGGGAAAAAGCTATCA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTAACACTAGCATTATAAGGCGGATCAGTCAACAC
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TTAGCATAGAACTCCTCCAATCTCGATAACCAGTCTC
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CTAAAACCGGCAGAAGAAAAAGAAAATATAAAAATA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	GCATAGCACAATTATTTTAGAAGGGTGATGTTTTTGAG
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATT	TAATATTAACTTTCCAATTATCAGGTTTGCTTAA
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	TTCTGTTGAAGCATCTGTTATGTTTGGCGATTCAT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC	CCAATGATCTTTGCCAAATCCTCTTGAGAATAAT
GTTTCAATCCTTCTTATGCTGGATGTATCAATTAATC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_011899.1|WP_012636441.1|1610766_1611060_-|hypothetical-protein	csx20	xls002255_csx20_CAS-I:CAS-III	unknown
NC_011899.1|WP_012636453.1|1625088_1626066_-|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl|CDD|187766
NC_011899.1|WP_012636455.1|1628571_1629288_-|CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl|CDD|131641
NC_011899.1|WP_012636459.1|1633695_1634031_+|YlbF-family-regulator	unknown	unknown	gnl|CDD|377611
NC_011899.1|WP_012636445.1|1614730_1615144_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	gnl|CDD|378242
NC_011899.1|WP_012636449.1|1619332_1620199_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	gnl|CDD|187788
NC_011899.1|WP_012636442.1|1611113_1612403_-|TIGR02221-family-CRISPR-associated-protein	csx1	pfam09455_csx1_CAS-III	gnl|CDD|187863
NC_011899.1|WP_012636451.1|1624187_1624784_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl|CDD|187768
NC_011899.1|WP_012636452.1|1624793_1625084_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl|CDD|187856
NC_011899.1|WP_012636450.1|1623478_1624165_-|CRISPR-associated-endonuclease-Cas6	cas6	cls000004_cas6_CAS-I:CAS-III	gnl|CDD|379957
NC_011899.1|WP_167935773.1|1613637_1614774_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	cd09661_cmr6gr7_CAS-III-B	gnl|CDD|213662
NC_011899.1|WP_012636447.1|1616114_1617296_-|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	gnl|CDD|187879
NC_011899.1|WP_012636443.1|1612405_1613620_-|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	gnl|CDD|187873
NC_011899.1|WP_012636457.1|1630214_1632290_-|glutamate--cysteine-ligase/amino-acid-ligase/CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl|CDD|187861
NC_011899.1|WP_012636456.1|1629304_1630213_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl|CDD|377458
NC_011899.1|WP_012636446.1|1615136_1616114_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	gnl|CDD|274210
NC_011899.1|WP_012636458.1|1632451_1633435_-|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|379100
NC_011899.1|WP_012636440.1|1610404_1610752_-|thioredoxin-family-protein	unknown	unknown	gnl|CDD|239245
NC_011899.1|WP_012636448.1|1617297_1619328_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	gnl|CDD|187810
NC_011899.1|WP_012636454.1|1626097_1628566_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl|CDD|224124

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_011899.1|WP_012636441.1|1610766_1611060_-|hypothetical-protein	csx20	xls002255_csx20_CAS-I:CAS-III	2e-25	84.0	0.6
NC_011899.1|WP_012636453.1|1625088_1626066_-|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	2.5e-90	297.3	1.2
NC_011899.1|WP_012636455.1|1628571_1629288_-|CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	2.4e-23	77.6	3.5
NC_011899.1|WP_012636445.1|1614730_1615144_-|type-III-B-CRISPR-module-associated-protein-Cmr5	cmr5gr11	cd09749_cmr5gr11_CAS-III-B	1.1e-36	120.6	1.4
NC_011899.1|WP_012636449.1|1619332_1620199_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	COG1367_cmr1gr7_CAS-III-B	1.8e-28	94.3	1.8
NC_011899.1|WP_012636442.1|1611113_1612403_-|TIGR02221-family-CRISPR-associated-protein	csx1	pfam09455_csx1_CAS-III	1.5e-93	308.6	18.2
NC_011899.1|WP_012636451.1|1624187_1624784_-|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	1.1e-35	118.1	10.6
NC_011899.1|WP_012636452.1|1624793_1625084_-|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	4.2e-22	73.1	0.1
NC_011899.1|WP_012636450.1|1623478_1624165_-|CRISPR-associated-endonuclease-Cas6	cas6	cls000004_cas6_CAS-I:CAS-III	7.3e-81	265.6	1.2
NC_011899.1|WP_167935773.1|1613637_1614774_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	cmr6gr7	cd09661_cmr6gr7_CAS-III-B	1.2e-51	170.1	0.2
NC_011899.1|WP_012636443.1|1612405_1613620_-|putative-CRISPR-associated-protein	csm6	cd09742_csm6_CAS-III-A:CAS-III-D	2e-58	191.5	1.7
NC_011899.1|WP_012636457.1|1630214_1632290_-|glutamate--cysteine-ligase/amino-acid-ligase/CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	1.2e-187	619.9	62.7
NC_011899.1|WP_012636456.1|1629304_1630213_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	8.8e-70	230.0	0.1
NC_011899.1|WP_012636446.1|1615136_1616114_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	cd09682_cmr4gr7_CAS-III-B	4.4e-74	244.3	1.7
NC_011899.1|WP_012636458.1|1632451_1633435_-|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	1.4e-50	167.3	0.5
NC_011899.1|WP_012636447.1|1616114_1617296_-|type-III-B-CRISPR-module-associated-protein-Cmr3	cmr3gr5	cd09748_cmr3gr5_CAS-III-B	3.8e-67	221.9	0.0
NC_011899.1|WP_012636448.1|1617297_1619328_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	cas10	cd09679_cas10_CAS-III	5.6e-117	386.3	14.7
NC_011899.1|WP_012636454.1|1626097_1628566_-|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	4.6e-55	181.8	31.9

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_011899.1|WP_012636453.1|1625088_1626066_-|CRISPR-associated-endonuclease-Cas1	gnl|CDD|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	3.13137e-97
NC_011899.1|WP_012636455.1|1628571_1629288_-|CRISPR-associated-protein-Cas5	gnl|CDD|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.82864e-17
NC_011899.1|WP_012636459.1|1633695_1634031_+|YlbF-family-regulator	gnl|CDD|377611	pfam06133, Com_YlbF, Control of competence regulator ComK, YlbF/YmcA. YlbF Is a family of short Gram-positive and archaeal proteins that includes both YlbF and YmcA which may interact synergistically. The family is necessary for correct biofilm formation, as null mutants of ymcA and ylbF fail to form pellicles at air-liquid interfaces and grow on solid media as smooth, undifferentiated colonies. During development, YmcA, YlbF and YaaT, family PSPI, pfam04468, interact directly with one another forming a stable ternary complex, in vitro. All three proteins are required for competence, sporulation and the formation of biofilms. The YmcA-YlbF-YaaT complex affects the phosphotransfer between Spo0F and Spo0B, thus accelerating the production of Spo0A~P. The three processes of biofilm formation, mature spore formation and competence all require the active, phosphorylated form of Spo0A, as Spo0A-P.	5.2881e-19
NC_011899.1|WP_012636445.1|1614730_1615144_-|type-III-B-CRISPR-module-associated-protein-Cmr5	gnl|CDD|378242	pfam09701, Cas_Cmr5, CRISPR-associated protein (Cas_Cmr5). CRISPR is a term for Clustered, Regularly Interspaced Short Palindromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family, represented by TM1791.1 of Thermotoga maritima, is found in both archaeal and bacterial species.	1.01579e-36
NC_011899.1|WP_012636451.1|1624187_1624784_-|CRISPR-associated-protein-Cas4	gnl|CDD|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	9.38995e-28
NC_011899.1|WP_012636442.1|1611113_1612403_-|TIGR02221-family-CRISPR-associated-protein	gnl|CDD|187863	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as TM1812 family.	1.27008e-66
NC_011899.1|WP_012636449.1|1619332_1620199_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl|CDD|187788	cd09657, Cmr1_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	3.67818e-18
NC_011899.1|WP_012636452.1|1624793_1625084_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.68278e-21
NC_011899.1|WP_012636450.1|1623478_1624165_-|CRISPR-associated-endonuclease-Cas6	gnl|CDD|379957	pfam17262, DUF5328, Family of unknown function (DUF5328). This family of unknown function can be found in Bacteria and Archaea. Some of the proteins in this family are annotated in UniProt as putative DNA repair proteins.	2.3566e-43
NC_011899.1|WP_167935773.1|1613637_1614774_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6	gnl|CDD|213662	TIGR01898, repair_system, CRISPR type III-B/RAMP module RAMP protein Cmr6. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1791 of Thermotoga maritima, is designated Cmr6 [sic], for CRISPR/Cas Ramp Module protein 6. This family is both closely related to and frequently encoded next to the TM1792 family of Cas proteins described by TIGR01867. The two proteins are fused in an example from Methanopyrus kandleri.	6.93071e-41
NC_011899.1|WP_012636447.1|1616114_1617296_-|type-III-B-CRISPR-module-associated-protein-Cmr3	gnl|CDD|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	8.44348e-62
NC_011899.1|WP_012636443.1|1612405_1613620_-|putative-CRISPR-associated-protein	gnl|CDD|187873	cd09742, Csm6_III-A, CRISPR/Cas system-associated protein Csm6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; loosely associated with CRISPR/Cas systems; also known as APE2256 family.	6.44033e-52
NC_011899.1|WP_012636457.1|1630214_1632290_-|glutamate--cysteine-ligase/amino-acid-ligase/CRISPR-associated-protein	gnl|CDD|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	1.00393e-133
NC_011899.1|WP_012636456.1|1629304_1630213_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl|CDD|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	6.45211e-71
NC_011899.1|WP_012636446.1|1615136_1616114_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl|CDD|274210	TIGR02580, putative_CRISPR-associated_protein, CRISPR type III-B/RAMP module RAMP protein Cmr4. This model represents a CRISPR-associated protein from the family that includes TM1792 of Thermotoga maritima. This family is part of the broad RAMP superfamily (pfam03787) collection of CRISPR-associated proteins. It is the fourth of a recurring set of six proteins, four of are in the RAMP superfamily, that we designate the CRISPR RAMP module.	1.39666e-68
NC_011899.1|WP_012636458.1|1632451_1633435_-|WYL-domain-containing-protein	gnl|CDD|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	2.99052e-46
NC_011899.1|WP_012636440.1|1610404_1610752_-|thioredoxin-family-protein	gnl|CDD|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	4.30687e-14
NC_011899.1|WP_012636448.1|1617297_1619328_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2	gnl|CDD|187810	cd09679, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; MTH326-like has inactivated polymerase catalytic domain; alr1562 and slr7011 - predicted only on the basis of size, presence of HD domain, and location with RAMPs in one operon; signature gene for type III; also known as Crm2 family.	7.9177e-110
NC_011899.1|WP_012636454.1|1626097_1628566_-|CRISPR-associated-helicase/endonuclease-Cas3	gnl|CDD|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.70503e-47

Protein sequences

>NC_011899.1|WP_012636449.1|1619332_1620199_-|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MYNITYNLKIVTPVYCKGSDNRKVELRPASITSIKGMMRYWFRALTAERDLNELHKKENKIFGSTKNASKFAIRIRDINLINKKNNLEDYYLLPHNEKKRNENPVPIKVLKSGLSFNLEFIFKSFEEELIDNVKDVFTLSLLLGGVGQRSRRGFGSIRDKNCKFDNKEELLKKIAGILQDFGRQVEVKDGEYIRVVDNQRYSYPVIKEIYIGKPEANFEKMLEKIGQASKKDKSLGSINPTRMASPVYVTVVKIKDDYYPLITKLEPIYPEGIEGNVEVLEKFIDELR
>NC_011899.1|WP_012636448.1|1617297_1619328_-|type-III-B-CRISPR-associated-protein-Cas10/Cmr2
MKKIFKEHPLSGEQLIKTFEDYIPEISLKNKSLAIFTIGPVQSFISAAKKTKEYWAGSYLLSYLIWQALKHIMEESKEGENSIIYPYLKNQPLYKDLRNEEITLPTLPNRFLAILENNEAEQLLEECKKMVENKLLDIAINLFNISKEDKIYKQLEELLEIYWVLLPLEKSKKTEIERYRSLTGMEPANDISHYSLVTSIIEELMGARKNIREFNYIEEKGVKCYICGERTGFEPGIMNIEDEKKICGVCGLKRKFSDYLKTEFGIEIHYPSVIDIATADYKEELVSSLDKDELNQLLNYMDKEFGNQDYQMPELVNGLVGDVKSKSPEEKKVLKIKGTYFDIEGNELKESIKVKKLLKKINKKYNLKLNKYYALLYMDGDDMGKWVSGEKLKHREMTPEFHYLISKSLTNYSLKFVKRIVEGKGRRGKLVYSGGDDVVAFVNLKNLFEVLRELRGYFSGNVFDNQVNYKASDGIIREKGEDILTLGSKASVSMGICIAHYKEPLHFVIKNARAMEKKAKKHIISGNRKKNAFAIGLIKHSGETREAVSKWFYDDGEDIIEKGIKPLLNLIQKEHISQSFIYTLKNEMELLEGLEAGDILDDEIIRLMKRKITVDEDEEKEDSKRKKLQKQTEASLKVLQQIYKNRYWIEDNKEPNNIYNFINLLEIIFFIGKRGE
>NC_011899.1|WP_012636447.1|1616114_1617296_-|type-III-B-CRISPR-module-associated-protein-Cmr3
MQVTVSPLDVLFFRNGKPFDADDSPIGETIDMPYPSTFYGAFRSRVLLDNSERYFEFLEGKAGEITEVIGSPDFKGSLKINFFSLIKEDKVFKDILLPLPQDMVVKKGDKSSGLLHLRFVSKKSWIKMNNSLSHLLINPVSKQVEWPGPAYIKIKDLEYYLNNELEDAEVKVFDRMNDIFDKEYRTGIEIDNVTKLAKEKKLYRREVLRFKNNRDKSYSFFLELTGDKGLLSESGLLKLGGEQKAAEYRKVKDVSNKIELYASTKKRILKSKKFKIYLSTPTVFKRGWLPEWINPDDFTGKLPASGIRVKLLTAAVGKHKIVSGWDMAKKTDKNKRGKAKTGFRVVPEGSLYYFQILDKKFDIEELINELHGQSISDLKSKEGFGISFIGGIK
>NC_011899.1|WP_012636446.1|1615136_1616114_-|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MYKETAILGLYCETSVHAGSGSDLGVIDLPIQREKYTDYPVFQASTLKGALRASFDTEIAIVNSLMKGVFKSFSFKNAKEGEEELEKAINLVFGDESNKSASALAFTDARILLFPVKSARNVFAWITSPMVLNRLKRDLEVAGINVDWEAPEIKKDAIISEKSSLDIDGNIILEEYTYSVNKQNIEGITNWIRDNIFAEDYTFWRDKLESDLVIIDDDEFKDFVSMSTELVPRIKIKNETKVVDKDGGALWYEENLPPETVLYSLVLATDILREEKDLENEDLKKAENVIQFFEEGLKERIQLGGNETIGRGIIRTRLVRSGKNG
>NC_011899.1|WP_012636445.1|1614730_1615144_-|type-III-B-CRISPR-module-associated-protein-Cmr5
MGKKDEQVKRKEIENGRAKKAYEFVKDVKGDKFKEKYKSHVKKLAPLIKTNGLGNTIAFIYSNDEAYQKIYKQLEYWLKEEKELINKDTLLEEVVSTDSKNYRQLTKETLALLNWWRRFVDGMIEDEGKGEKKDQQA
>NC_011899.1|WP_167935773.1|1613637_1614774_-|type-III-B-CRISPR-module-RAMP-protein-Cmr6
MKMKERGRRKISRHNFKEGDIVEGRVTRIKPYGAFVRLDEKKKIDGLIYISNIADKYVKDITNYINEGDQIRVKIINIEKDGKIALSFKYKSYIPNDTNKIIKKTAIENFYLQTNYYIYDFDESDKKDILANLTKNQNQFFSTKEIKSFLSRQEKQISYLSSIGYSVDNFVMTNDYRMVVGLGGANVLETNLMLHHIYGIPYIPGSSLKGLTRAWAVEKLREELDVKSYEKIESLLGEEKIDVKTLDEYQMNQFEKYRWIFGTKSQSGNAVFFDAYPEGRINIDIDIMTPHFKEYYQEMETTKKVNNPPDDTQSPVPIPFLVLDNQMFRFSVAVKCKECAGKRDNSCEYLNLTVNLLKEALRNLGVGAKTMVGYGYFE
>NC_011899.1|WP_012636443.1|1612405_1613620_-|putative-CRISPR-associated-protein
MKKILTTVGTSLLTHLREEEEIGKSEYDYFLDNKDDVDKVYYDRKGKDKIHRLKKVALNYLSKKDINNNEDLNNMSAELKSIKKIIEYKNIKQYEIIFICSDTLAGKVVTDILMDYIIESKFNYTDIKTKLIKKLQVQNKARFEKSGVHNLIEYINTMVNNTGSNNLILNITGGYKSVVPYMTIMGYVNEIPVYYIFEETNELIELPLIPIKVDEELFKKYMCEIHQIMDKGVINKDLLEQILNKVDWNDKQLIKTRLLQNDLQEPDYYYPSPITRIFWEKFKSNYIFNIELSDSAYEFYSRKEERARFILEKVSDYDLRKKHYHYIKGTDMDCYKSGGEELFRVFYKVYDKEDRNAIVKVAEIFDLAHKTNEYDNFCKAPRNSNEYQFNKCIIKKSNKSIERC
>NC_011899.1|WP_012636442.1|1611113_1612403_-|TIGR02221-family-CRISPR-associated-protein
MKLGKFISVLGKSNYVPCNYGQYKNVNYIQEALVRKYKDKISDVIIFATKEAIKSNWLGEGSLKNKFDGLQEQGIEFNYKIKEIPLGASEDEVWEIFDIIVEEINEGDSLYLDITHGFRFQPMLIMSIMNYVKLIKNVTVESIEYGMFEILGTRQEVEIIPVEERNAPIVDLTLLDQLNDWVVATDSFLTTGSVTKIDELTKNEIGQVLALTKGRNEFFQNLKSLVNNLKDFYDCVNTSRGNKLNETIINILKNLKDLDEFNQVNDLKNKRIKPFLQIIDKIYDKFKGFSSKDKSDIANYFMVLNWCNENNFIQQGLVILRENIISFIIFNMGYDYTINDYRFDVSKALSYLDGRKKREIYKNKEFYLKVKEFISNNYPYLPKLFSEVGDTRNDISHFGLTKCPISNPNKFKDKLKEFIEQIEPLVSNL
>NC_011899.1|WP_012636441.1|1610766_1611060_-|hypothetical-protein
MADLYLIFSHTLTENQIKDAKVNLKVRKIIELPSNLQKLWSNIPSNIKSLKNHLYPIKSWVNKNVKPGDYIFVSVVKLAFEIGCKSITGRKYNFSIC
>NC_011899.1|WP_012636440.1|1610404_1610752_-|thioredoxin-family-protein
MQELTDKNFQKEIKNNKYSIVVFTTEGCGSCLLAKKYVKEVAQQFEELKLFECRVDKAPQSIKKYSVQGAPTVKLFVKGESVYTGFGVRTPTDLYYQLESFIPKPNYYEELFGDN
>NC_011899.1|WP_012636450.1|1623478_1624165_-|CRISPR-associated-endonuclease-Cas6
MELKVVQLTYDLEEDLPLSYGHKLRGYFAHEFEEVLFHQHKKDGGLRYKYPLIQYKIINNKPVIIGLGSGGDLIIEHFLSIDKIVLGDKKFLNPSGKLKVDSIELKVNNKYDMPPYKYSFISPWLGLSQKNYNIYKTRIEGGTKDEKVKFLKKIITGNILSFAKGVGWWIEESIITVPKLREIPVNFKNQTMIGFVGEFYSNVFIPEYIGLGKSTSRGFGTLRREKII
>NC_011899.1|WP_012636451.1|1624187_1624784_-|CRISPR-associated-protein-Cas4
MVKVSNISLTPSEVMEYLYCPRFIYYMSYLKIPQHEKNRFKVMMGRDMHKRKLKINKKYLRKKIGVKKKILDKKMYSKKHNIHGIVDEILFLEDGTAAPLDYKYAKYKKRTFLTHKYQAAMYGLMIADIYNIEVNRAYIVYIRSKNLLKEIKLDTKIYSNVGKIMKEIISIIQKGYYPDRTKYKRRCFDCTYRNICIK
>NC_011899.1|WP_012636452.1|1624793_1625084_-|CRISPR-associated-endonuclease-Cas2
MLVWFIYDIVEDKPRKKIADKAIEQGLYRVQKSVFLGDIEPNLLDELLVYAEELIDPENDSVYAFPMCQEDFKKVEIIGQAFDKAMVNDKLNSFFM
>NC_011899.1|WP_012636453.1|1625088_1626066_-|CRISPR-associated-endonuclease-Cas1
MQLVINTYGSYLHVKQKSFEIKTEEDKKRVSAKKVSSILITTGAAISTDAVKLALENNIEIQFLDEFGCSLGKVWHPKLGSTTYIRRKQLELAESEEGTELVKEFMLDKIDNMINHLHDLAIKRSKSKEKYINKKIKEICELRNKLEKVTGYIEDVRNTIMGYEGNISRKYFASLSFLLPDRYKFNGRSFRPAEDEFNCLLNYGYGVLYGKVEKALIIAGLDPYVGILHTDGYNKKSFVFDFIEPYRHHIDRVVMKLFSRKKIRKLHFDKIQGGLTLNDEGKKLLLTELNDYFDKKIRYKGREIKINNTIQYDCHSLANRIIEEG
>NC_011899.1|WP_012636454.1|1626097_1628566_-|CRISPR-associated-helicase/endonuclease-Cas3
MEKLFSHYSSNKKRELEVHLKNVAEGCKNIILNKRLDLSIISKDELTDIAFLIGAVHDFGKSTTFFQNYLVHGEENIFSHHGLISAILAYILLKKKYTRLMAMIGYMVVKRHHGNLESPVEDCGETFYHIKMQINDIKQNTYNHVKNIYDNNILKDTEYCFEELFSELEEFVVEVDDISELFREIVIEDKYKNEDKAIELFLVTNLLYSILIDTDKKDAASLNNDYFKGATEEYINVQKYINKKRKEQPKKYNPGLPINKARNSFFQDVTNHSQIKDTNFLYSLTAPTGIGKTFASFAFANKLRELSAYGKRIIYCLPYTSIIDQNFNEFEKIINFNLKEVYKKNPSKYLLKHHYLTPLELKKNIDLEKDSRISRDLEKYLDDRLLLESWESGNIVTTFVQLLESIIGNKNSYLKKFHNIVNSVVILDEVQNIPVEYYHVVGKVLKILGKNFNTHILLMTATQPEIIYGNDVVNLVNEKKYNEMNVFDRVNLKIIDKLNPYNIEDFLGYLELNFNSKTGLIVCNTISSALDIYKYVDELFTSKGYHVYSLTTNLTPIDRLEKIDEINMKIDKGEKIIVVSTQLIEAGVDLSFEEVFRDFAPLDSIIQVAGRCNRSGELPQKGKVNIIMLKNDKEEMYCNKVYDKVLLDICREVLSEKKSFIDMSKNYFSRIRESYLRQSDKLMNAICNLNYSKEKVDQDPISKFKIVKEQGGKDNIIICKNKDIENKIEELKEIYEEIKLSYNDRKKLNRLIAKKEILNKELALYKINVYTNQLKEYEKHYIIKKFRFIKYVSYEDQKKYLYDDNIGFLKEPKKKFESTMFA
>NC_011899.1|WP_012636455.1|1628571_1629288_-|CRISPR-associated-protein-Cas5
MDINQVLVFKIKGKIAHFKKYYSNKSSLTYKIPPRTVLMGIVASILEKPRDSYYELLSPQQAKFGVKIESESYTHFECMNYLKEDGGHTQVRLQLLLPANNMLSYKVFFTHQDESLLKELATKIKNKIYGYGIYLGQRQFRATAEFDDLIEDIDIIKDYTGNLKTLTYKDNIKKLNDTTTYNLILDNMPVSFKKVNSGREPEKVVEVCYEENGANINGSFYEVIKLKDDYISFYTPVR
>NC_011899.1|WP_012636456.1|1629304_1630213_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MTEKQKVPNNSEILFLYDAKRSNPNGDMDNENKPRMDWDTGTNLVSDVRLKRYIRDYLQKVKGKNLFVSEEAEKAENRVHQILGRKPSSNKPVTDEELTKIAEECCDVIYFGAVLGTSGGNTHLTGPVQFNWGYSLNKVELQESKTITSSFSSGEGVGKDYRVKYSFIAFSGGINGLAAKDTKLTENDVKLLDEAIIKSIPLNRTRSKIGQTPRLYLRVEMNDNETALNDLREYISLDYNVREEDVRDINNIELVIDELLEYLSTIKSKIKKINYWKDNKLTVKDNGFEKLLNTFPVNELNY
>NC_011899.1|WP_012636457.1|1630214_1632290_-|glutamate--cysteine-ligase/amino-acid-ligase/CRISPR-associated-protein
MINSFKELGEIELQGLSDSEKKQKFLETQTIIPNEPDSGDKDADKYREVIINLDTEKEEIEIKLGKELYEKNREEFFGFDLKASNSSKTYFTTDNYNYHLLTIPHLIYYIEKEIDKLKIKNIEDFLDWLNMIKNKFYIVVGRDYFGRPISYLSVDKNVSHQKKEIVKYLRSEIDKYEKRGNAEKAKEINKYINGEVVNTEILTIKDIKKYYEKQISLAISTTQNFLKNELNIFSIHINGKRILESIYKAPYVEVVYYILQQRFFDTSNSDKMARDNALCGVCNENKLITGKIDIPTKFYVTSSPYFYENLERKNAYKSFGICQDCYLKVMAGIAKVKKDFSGKLFNQLDYYVIPTNIAYCKKYKTEIEVIKSILSDNNKSFKKNIEAINSIANSNLKVNFLFWFKPKGQNAAFVVSESINDVAYNHISQIIKNLYNLNMKLIYPNKYFNLYKLTFNDIYWLLFPNTESHKNPDPKLYRKELLSLLNSILKGRSVNYNYLIKQFNFILRKRYFKNSKRVEEIIYNPMKMNLLLTWLNEITEIKGGFKMSEGTSSIPIENSDIKEFFSTHAETYKNNKYRQGLFLLGVLMNEVLKKQQKENKSASILDKLSFDGMSVRQVSKFVNDITEILHIHDKYTCNQLLHSQMIDRIQGIENSSLNKDEVVFYILSGISFGRYLGHKYYKTKNNKGDDK
>NC_011899.1|WP_012636458.1|1632451_1633435_-|WYL-domain-containing-protein
MTVKRSKLYRILKMINLLSSGVKRWRARDLAELFGVSPRTIYRDIQYMEQMHIPVIKDEEKNTYAIMEDFYFKPPRMTREEAMALLLVAHAFEDEVYPYREELNNAVSKIINSLPSSVKKVLLDLEDRILFHQGAVVDMTKHRDTINIINDSIASNQSVIINYYSLSSDMLRERKVDPYKIFVQDGAYYLIAYCHLRCNVLLFRVDRIRNIKVTSDKYIIPDDFDVEKYMQNAWGVERGDKEERVVLLFKGTSAKLVKERKWQVKHQIVELGDDKIRFEVTTGSMQEIMGWILQHGSEVEVVRPESLKENVINEIKKMSNIYKKTHV
>NC_011899.1|WP_012636459.1|1633695_1634031_+|YlbF-family-regulator
MSIIKKAEELGKEIVDSAEYKELKSTEEAMQNDKEAQSLLNEFRSKQQRLQMAQANGKNITEDQKKELMALQARMQENEKIKNFMTAQQKFNQVMQTVNQAITGIIAGQHA

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011899_1	1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT	1623067-1623100	34	NC_011836	Clostridium kluyveri NBRC 12016 plasmid pCKL1, complete sequence	24093-24126	7	0.794
NC_011899_1	1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT	1623067-1623100	34	NC_009466	Clostridium kluyveri DSM 555 plasmid pCKL555A, complete sequence	22476-22509	7	0.794
NC_011899_1	1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT	1623067-1623100	34	MN693190	Marine virus AFVG_25M52, complete genome	32061-32094	7	0.794
NC_011899_1	1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT	1623067-1623100	34	MN693247	Marine virus AFVG_25M51, complete genome	31844-31877	7	0.794
NC_011899_1	1.17|1622919|36|NC_011899|PILER-CR,CRISPRCasFinder,CRT	1622919-1622954	36	NZ_CP025850	Escherichia coli strain 600468 plasmid p600468_158, complete sequence	69399-69434	8	0.778
NC_011899_1	1.17|1622919|36|NC_011899|PILER-CR,CRISPRCasFinder,CRT	1622919-1622954	36	NZ_CP024249	Escherichia coli O182:H21 strain D181 plasmid unnamed1, complete sequence	147720-147755	8	0.778
NC_011899_1	1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT	1623067-1623100	34	NC_019428	Anabaena sp. 90 plasmid pANA01, complete sequence	75885-75918	10	0.706

1. spacer 1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT matches to NC_011836 (Clostridium kluyveri NBRC 12016 plasmid pCKL1, complete sequence) position: , mismatch: 7, identity: 0.794

taatattaactttccaattatcaggtttgcttaa	CRISPR spacer
tgacttgacatttccaattatcgggtttgcttaa	Protospacer
*.*. * *  ************.***********

2. spacer 1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT matches to NC_009466 (Clostridium kluyveri DSM 555 plasmid pCKL555A, complete sequence) position: , mismatch: 7, identity: 0.794

taatattaactttccaattatcaggtttgcttaa	CRISPR spacer
tgacttgacatttccaattatcgggtttgcttaa	Protospacer
*.*. * *  ************.***********

3. spacer 1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT matches to MN693190 (Marine virus AFVG_25M52, complete genome) position: , mismatch: 7, identity: 0.794

taatattaactttccaattatcaggtttgcttaa	CRISPR spacer
gattaaagaatttccaattatcaggtttgattaa	Protospacer
 * **  .* ******************* ****

4. spacer 1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT matches to MN693247 (Marine virus AFVG_25M51, complete genome) position: , mismatch: 7, identity: 0.794

taatattaactttccaattatcaggtttgcttaa	CRISPR spacer
gattaaagaatttccaattatcaggtttgattaa	Protospacer
 * **  .* ******************* ****

5. spacer 1.17|1622919|36|NC_011899|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025850 (Escherichia coli strain 600468 plasmid p600468_158, complete sequence) position: , mismatch: 8, identity: 0.778

ctaaaaccggcagaagaaaaagaaaatataaaaata	CRISPR spacer
tttaaatatacagaagaaaaagaaataataaaaata	Protospacer
.* ***.  .***************  *********

6. spacer 1.17|1622919|36|NC_011899|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024249 (Escherichia coli O182:H21 strain D181 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.778

ctaaaaccggcagaagaaaaagaaaatataaaaata	CRISPR spacer
tttaaatatacagaagaaaaagaaataataaaaata	Protospacer
.* ***.  .***************  *********

7. spacer 1.19|1623067|34|NC_011899|PILER-CR,CRISPRCasFinder,CRT matches to NC_019428 (Anabaena sp. 90 plasmid pANA01, complete sequence) position: , mismatch: 10, identity: 0.706

taatattaactttccaattatcaggtttgcttaa	CRISPR spacer
ggaaataaactttccaattatcaggattcttctc	Protospacer
 .* ** ****************** ** .*.  

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2407008 : 2415563	8	Synechococcus_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_011899|2407008:2415563|DBSCAN-SWA
ATTATGGTTGATTTATATATACCTTTCTACCCTGTATTGTTAACCTGTTTTCAGCAAAAAGCTGAATAGCTTCCGGGTAAAGTTCATGTTCTTTCTCCCTTATCCGGGAAGCCAGTCTTTCTTCTGTATCGTCACTGTAAACCGGGACTGGAGCCTGTAAGATGATGGGGCCAGTATCCATTCCTTCATCTACAAAATGAACTGTACAACCACTGACCTTAACCCCGTATTCCAGGGCCTGCCTCTGGGCATGAAGCCCCGGAAAACTGGGCAGCAATGAAGGATGTATATTCATAATCTTTCCTGAAAACTGATTAATAAAATAGGGGCTTAACAAACGCATAAAGCCGGCCAGGGCTACCAGGTCTATATTCTTTTTATCCAGATAATCCAGCAATTCCTTCTCATACCCCTGGCGGGAGTTAAAATCAGCTGGATCAATAAAGATATTTTCAATGCCGGCCTTTTCGGCCCTGACCAGGCCATAGGCGTTCTTTTTGTCACTGATCACCATTTTTAATTCAGCCTCAACCCTGCCAGCTTTAATAGAATCTATAATTGCCTGAAGATTGGTTCCATTCCCGGAAATAAATACAGCCAGATTAATTTTATTGCCCATTGTAGATAACCACCTTACCCTCTTTTTTACCGATACTATTTATTTCTCCAATATGGTATACTTTTTCTCCCCGGGCCTTTATATCTGACATAACATTTTCTAATATATCCGGAGAAACAACCAGCACCATACCGATCCCCATATTGAAGGTTCTCTCCATTTCAACTGTAGCAATATCCCCCTTGGCCTGAATATAGGTAAATACTGGGGGACACGACCAGCTTTCTCTGTTTACCCTGGCCTGAAGGCCATCAGGAATAATCCGGGCTATATTTTCCGGCATTCCCCCACCGGTAATATGAGCTATTCCCTTTACTTCATATTTTTCTAGCAACGGAAGAACCACAGGTACATAAATACGGGTTGGTTTTAAAAGCTCCTCACCAAGGGTACAGTCTAGCTCTTTTATTCTATCATCTACTTTCAACCCCTCTTTTTCAAGAAGTACTTTCCTGACCAGGGAATAACCATTACTATGTATCCCAGATGAAGGAAGGCCCAGTAGCTGATCCCCTGCTTTTATTTTCGAACCGGTAATTATATTCTTACGGTCAACGATCCCAACTGCAAAACCGGCCAGGTCATAGCTCCCCTGCTGATAAAAGCCCGGCATCTCCGCTGTCTCCCCACCGAGCAGGGCAACACCGGCCTGTTTACATCCCCTGGTAATTCCGGTAATAATCTCCTCTCCGGTCTCGAGCTCAAGTTGCCCGGTAGCCATGTAATCAAGGAAAAAAAGGGGTTTTGCCCCCTGGGCCAGGATATCATTAACACACATGGCTACCAGGTCAATCCCGATGATATCATGTTTATTAACAAGCTGGGCAATTTTCAGTTTAGTACCAACCCCATCGGTTCCAGAGACAAGAACCGGTTTTTGGTATTGTTTAAAATCAGGGGCAAAAAGCCCCCCAAATCCCCCCACCCCACCGATAACCCCGGGAAGGTGGGTTTCTTTTACTTTATCTTTAATGCGATCCACAAACTCGTTACCTTTATCAATATTTACCCCCGAATCAGCATAGGTTATGCCCTTTTTCATTAAACCCCTCCATTTTTAAATATTTCTTGCCCGGTATCAGATTATTGTCCTGATTTAATCTCAGGGACGTTTTTTTCTAAAGCCAGTTTCCCATTTCCGGTCCTGGTAGGGTAATCACCCGAAAAACAGGCGACACAGCAACCTTTTTCTTTTCTCTCAACAGTAGATAATAATCCCTCGATACTGAGATAGGTTAACGAATCAGCTCCAATTTCCCGGGCAATATCTTTGACATTTAGCCGGGAAGCAATTAATTCCTGCCTATTGGAGGTATCAAGACCATAATAACAGGAATGGGTTACCGGAGGTGAACTGACAAAGAGATGAACGTCCCGGGCCCCGGCCTCTTTAAGCATATTAACGATCTGACGGCTGGTTGTTCCCCTGACAATTGAATCATCTATCAGAGCAATATTCTTCCCCCTTATAATATTCTTAATAGGATTTAATTTCATTCTAACCTTCAGATTCCTCATTTCCTGGGTAGGATTAATAAAGGTTCTACCCACATATCTGTTTTTAATAAGGCCATATTGAAACGGAAGGCCGCTTTCTTCAGCAAAACCCTGGGCTGAAGAAATTCCCGAATCAGGTACAGGAACGACTACATCTATTTTTTTCAGGAGGTCACCGGCTTCCCGGGCCAGCTGCCTCCCCATATCTTTACGGATCAGATGGACGTTATTTCCATTAAAAGAGCTGTCGGGACGGGCAAAATAGATATACTCAAATATACAGAACCGGGGTTCAACCTCCGGATTAAAGGAATAGCTCTGAACACCATTTTCATCTATCACTACCATCTCCCCGGGTTCAATATCCCGTACATATTCAGCCCCGATTATATTCAGGGCACAGGTTTCTGAAGCCAGGACTATGCCCTCACCCAGCTTTCCCATGACCAGAGGCCTGAAACCCCGGGGATCCCGGACGCCAATAAGCTTATCCCTTGTTAAAACTACAAGAGAATAGGCCCCTTCAATTGTTTTTAAACTATCGAGAAGAGCACTGGGGATATCGTTGTATTGAGAACGGGCAATAAGGTGGGCAATCACTTCCGTATCCAGGGTAGAATGAAAAACAGAACCCTTTTTCTCGAGGGCAATCCTTAATTCATAACCATTAACAAGGTTACCATTGTGGGCCAGGGCTACCTGACCCTTGATTGAATTAATCAGGATGGGCTGGGAATTAGCAGCCAGGCTGGAACCGGTAGTTGAATACCTGACATGACCAATCCCTGCCCAACCCGACAGGGTCTCAATGATGGATTTATTAAAAACATTATCTACCAGACCCATCCGCTTATAGAGGTTAATCCCTTTATCCTGGCTTACAGCAATACCGGCACTCTCCTGCCCCCGGTGCTGTAAAGAATGCAACCCGAGGTAGATAAGACTACCGGCATCATTCCTGTCCGGTGAAAAAATACCAAATACACCACACTCTTCCCTGGGTTTTCCGCTCATTATTTCATATGGCATGGTATTGTCCTCTCCCACCTATCTTTTATTTCAGTGAGCTCCAGGTCAATATAACTATCAATTATTAGTCGGTTCCCACCCGTTTTACCGATATTTCTATATTTTAAGCCAGATTCTTGTAAAACAGATTCCGCCTTTTCTTTATCTCCAGGTGAAATTGTTATCAATACCCTGGAAGCCGATTCTCCGAATAACATCGCATCAGGCCTTATCTGGAAATCACCCAGCTCAATTATGGCACCGAGATCCCCGGTGAGACAACATTCAGTAAGAGCTATAGTCAGACCACCTTCGGCACAATCATGGGCAGACTTAACTAACCCCTCCTGGATAAGAGTCAATAAAGATGACTGTAACCTCTTTTCTTCTTCAAGGTCAAGAGTCGGGGGTAACCCCCTGTCTTTATCGTGTATTACCGATAAATATTCACTGCCCCCAAGTTCTTCTCTGGTCTCTCCAATGAGGTAAACTAGATCTCCCTCATCTTTAAAAGCAATATCGGTAGCATACTCCTGCTTTTCCAGTACTCCAATCATACCTACAATTGGAGTTGGATAAATGGCCTTTCCTTCGTGTTCATTATAAAAGCTGACATTACCACTAACCACCGGTGTGCCGAGGGCCAGGCAGGCCTCACTGATTCCGGCCACCGCCTCTTTGAACTGCCAGTAAATTTCTTCTTTCTCGGGATTTCCGAAATTCAGACCATCTGTAATTGCCAGGGGCTGACCACCACTGCAGACTATATTCCGGGCTGCCTCGGCCACAGCCAGTTTACCCCCCTGCCTGGGGTCAAGATAAAAATAGCGCCCGTTGGAGTCAGTGGTAACCGCAATAGCCCGTTCAGTGCCCTTTATCCGTAAAACAGCTGCATCAGATCCGGGTAAGACCATTGTATTGTTCTGGACCATATGATCATACTGACTATAAATCCATTCCTTACTGGCCAGGTTTGGTGAATCCAGCATTTCCAGCAAAACTTTATTATAATCATCTGGGAGTGGTAACGACTCCAAATCCAGTTTATTCTCCTCATCCAGCCAGGCAGGCCTCTTACCTTCCCTGACATATTCGGGAGCCTCAGCCAGATAATGGGCTGGCACTTCAGCCACAACATCTTCTCCATTTTTTATCCTTAAAATACCGTCATCGGTTACCCGGCCAATAACCCGGGCATTAAGGCCCCAGTGTTTAAAGATCTTTTTAACCTCATCTTCACGCCCTTTTTTAGGGACAACCAGCATTCTCTCCTGGGATTCCGATAACATAATTTCATAAGGAGTCAGGCCCGGTTCACGCAGGGGAACCTGGCTGACATCCAGCTCCATACCACTACCGGCCCGACTTGCCATTTCACAGGAAGAACTTATCAGACCTGCTGCCCCCATATCCTGGATACCAACCACTGCATCGGTCTTATATAATTCAAGGCAGGCCTCCAGTAACAGTTTTTCCATAAAGGGGTCACCAACCTGAACCGAGGGACGCCTTTCCTCCGAATCTTCACTCAGTTCTTCGGAGGCAAAACTGGCCCCCTGGATACCATCCCGACCTGTGGTTGCACCAACAACCATAACCGGGTTTCCAACACCCCGGGCCACAGCTTTTATGATATCTTTGTGATCAACCAGACCAACACACATGGCATTTACAAGAGGATTCCCTTTATAGGCTTTATGAAAATAAGTCTCACCACCGACGGTGGGGATCCCGATACTATTCCCATAGTCACTGATCCCACTGACCACCCCTGAAAAAATATATCGAACCCGTTCCTCATCAAGGGGACCAAACCTGAGGGAATCAAGTAAGGCTATAGGGCGGGCTCCCATGGTAAAAATATCCCTGATTATACCACCAACACCGGTCGCTGCTCCCTGATAAGGCTCAATGGCAGACGGATGGTTATGACTCTCAATCTTAAAAACAACCGCCTTGTTATCACCGATATCGACTATACCGGCATTCTCACCCGGACCCTGAAGGACCTGCTCCCCTTCGGTGGGGAAATTCCTTAAGACTGCTTTGGAATTTTTATAACCACAGTGTTCGGACCACATAACCCCGAAAAGACCCAGCTCCAGTTCATTGGGCTCTCTCCCCAGTTTTTCAACAATCATGTGATACTCTTTTTCAGTAAGTCCGTGAAATTTTAGCTTTTCTAATAGTTGTTCCCGGGATTTCATAGTTTCACACCACCAGCCTTAAGAATTGATTGAAATATTTTAAGTCCATCGTCACTCCCATTACCGAGAATGGTTTCACTGGCCCTTTCAGGATGGGGCATAAGCCCAAATACATTATGATTTTTATTGGTAATGCCGGCAATATTACCGATTGAACCATTAGGATTGGCTTCATCTATAACCTCTCCCCCCGGCGTTGCGTACCTTAATATAATCTGGTTATTTTCCTTCAATTCCTCTAAACCCCTGTCATCTATATAATAGTTACCCTCTTTATGGGCAACAGGGAGATTTATTATATCTCCTTTATTGAACTTACCTGTAAAGGGAGTCTTATTATTTTCAACCCTTAAATAAACATACCGGCAGTTAAAATTAAGGTGGGCATTATGATGCATGGCCCCGGGCAAAAGCCCTGCCTCCAGTAAAATCTGAAAGCCATTACAGATACCGATTACTAATCCTCCCTTTCGGGCAAATTCCTTAACCCGTTCCATAACCGGGGCAAACCTGGCAATGGCGCCTGCCCTGAGGTAATCCCCGTAGGAAAAACCACCGGGGATAATGATACAATCATAACCGGCAAGGGAACGATCATCTTCATGCCAGATAAACTCGGTCGGCTCTCCCAGTACCCGGGCAGTCACATGATAACAGTCCCGGTCACAGTTGGAACCTGGAAATACAATTACTCCAAATTTCATAAAACCACTCCCATTTAATTGGCTTTTTTTACTTCAACTTTATAATCTTCGATAACTGGATTGGCCAGAATTCGGCCGGCGGTCTCCTCAGCCCTTTTAACTACATCCTCCCTGTTTTCTCCCTCCATAAAGAAGGTTATATCTTTACCAACCCTGACTTTACTGATATCTTTATAACCCAGGGAATGAAGAGATTTTTCAATGGTACTCCCCTGGGGGTCCAGAATCCCCTCTTTAAGATTTACCTTAACCTCTATCTTCCAGCGCATAACAGGCCTCCTCTTTTAATTATTTTAATGTAATCAGTCTGCCCCTGACTATCCTGATTTATTTCCTTATTTCTAATCCAGTAAATTTCATAAAAAGTTTACATTAGTTTAATGGGAGCCTAAATCTCTAAACTAGTTCTAATCCCTAAACCAGTTCTATTTAACCCGGGACCAGACTTCCCGGTAGGCATTCTCGACACCGCCTAAATCCCTACGGAAGCGGTCTTTATCAAGCTTTTCTCCACTACTTTTATCCCAGAACCGGCAGGTATCCGGAGATATTTCATCAGCCAGTAAAATATTACCATTATTCTTCCCAAACTCAAGTTTAAAGTCAACCAGTTCTATACCTTTATTTGAAAGATAATTTCTCAAAATATCGTTAACTTTAAAACCCATAGCTGTAATTTCCTTAATTTCTTCTTCATCTGCCAGCTTCAGAGCTCTAATGTGTGAATTGTTTAGTAAAGGATCACCCAGGTCATCCCGCTTATAGTAAAATTCAATAATGGGCTCTTCAAGAACATAACCTTCTTCAAGACCCAGCCGCTTTGAAAGGCTACCGGCCACTATATTCCTGACAACTACTTCCAGAGGAATTATATCCACATAGGTTGTCAGCTGCTCTCTGTCACCAAGCTTTTTTATAAAATGGGTTTTAACTCCATTATCCTCGAGTAGATTAAATAGAGCTGCACTTATCTGGGCATTATAAAATCCTTTTTCCTGGATAGTTCCCTTTTTCTTCCCATTAAAAGCAGTAGCATCATCCTTATACTCAATAATAACCCTGTCTTTGTCCTCGGTCCGATAAACCTTTTTAGCCTTTCCTTCATAAAGCATTTCCAGTTTTGTTAACATTACAAACCCCTCTCCTTCCTGATTTTAGTCACAATCTCTTCAGTCCTTTCCCGGGCAATACCGGTATACTGCTCCGGATTATAGAGAATATCCTTCTGGCGTTTATCGAGTTTAGCCAGGTAGGTTTCAATTTCTTTGTCGGCTTTAATTAATTCAACCAGATCCTTACCCTCTTTATCAGCCTTCAGGGTAAGTTTTCTTACATATTCATGGGCATCGGGGTGGCCAGCAGCTGCCAGGAATATATAGAGTGGTTCAGCAATTATCATATTTTTACTTAAGTTAAAATTATTCTTCATTTTCCGGGAATTAATTTTCATCCGTGAAGATACTTTATACAGCCGGTCTACCGTCATCATTAATCCTGAGGCTATTTCAGCAATAAAACGACCTGAGGCTGAATTGGTTAGATCTCTCTGGTGTTCAGAAAGCTGATCCAGATACATGGTCACCATCCGGGGCATAAAGGTTTTCCACATGCTTTTAACATTCTCATAATTAATGGGGTTTCTTTTATGGGGCATGGTCGAAGAACCGACCTGGTCTTTAGCAAAATACTCCCCTGTTTCCCCTATTTCTGTCCTCTGCAGGTGCCTCATATCATCACTGAAGTCAGCCAGAACCCCAAAAACAGTAATCAGGGAATGGACATAGTCGGTCATATATTCGGGAGGGACTATCTGGGTGGAAACGGGAGCGGGCTTCAGGCCCAGTTCCTTTAATACTTCTTTTTCGAATTCTTCCGGATCTTCAAAAAATAGACTGCTGGCATTATAGGCTCCTACCGCCCCGGCCATCTTACCACACAGGCTGGAAACCACCTTCTCCAGGTTAACAATCCGCTCATGAAGCCGGCTGGCATAATAAGCCATAACCAGCCCAAAGGTAAGGGGTTCAGCATGCTGCCCGTGGGTACGGCCAATCTGGAGTGTATCCCTTTCCTGTTCGGCCAGATTAAGCCACTGCTCCAGTAACCGCTCCAGTGCCGGTACAATCAATTTTTCTGTAGCTTCTTTATATCGAAGGCTATTGGCCGTATCTACAATATCAAAGGAAGTTGCCGAAAGATGGACAAAGGGACGGGCCTCAGCACTTATTTTCTTTCGAATACAGTTAACAAGAGCCCTTATATTATGCCTGGTCCGGGCCTCTTCTTCATATACTTCCCCTACCTTTATCCCTTTAACAGCCTCTTCAACCTCCTTAACCACATCAAAACTACATACCCCACGCCCGGCCAGGGCCTTAACCAGGGCCAGCTCAACTCTAGCCTGAAAATAAATTGTAGCCTTTTCCGAAAAGTATTTGCCGAGGTCATTAAACAGATCTTTTTTTAAAGAATATCGGTGATCAAGTGGACAGATATTTTCAAAAATATTTCGTTCCATTAT

Protein sequences of DBSCAN-SWA_1

>NC_011899|2407008:2415563|2410136_2412338_-|WP_015923927.1|DBSCAN-SWA
MKSREQLLEKLKFHGLTEKEYHMIVEKLGREPNELELGLFGVMWSEHCGYKNSKAVLRNFPTEGEQVLQGPGENAGIVDIGDNKAVVFKIESHNHPSAIEPYQGAATGVGGIIRDIFTMGARPIALLDSLRFGPLDEERVRYIFSGVVSGISDYGNSIGIPTVGGETYFHKAYKGNPLVNAMCVGLVDHKDIIKAVARGVGNPVMVVGATTGRDGIQGASFASEELSEDSEERRPSVQVGDPFMEKLLLEACLELYKTDAVVGIQDMGAAGLISSSCEMASRAGSGMELDVSQVPLREPGLTPYEIMLSESQERMLVVPKKGREDEVKKIFKHWGLNARVIGRVTDDGILRIKNGEDVVAEVPAHYLAEAPEYVREGKRPAWLDEENKLDLESLPLPDDYNKVLLEMLDSPNLASKEWIYSQYDHMVQNNTMVLPGSDAAVLRIKGTERAIAVTTDSNGRYFYLDPRQGGKLAVAEAARNIVCSGGQPLAITDGLNFGNPEKEEIYWQFKEAVAGISEACLALGTPVVSGNVSFYNEHEGKAIYPTPIVGMIGVLEKQEYATDIAFKDEGDLVYLIGETREELGGSEYLSVIHDKDRGLPPTLDLEEEKRLQSSLLTLIQEGLVKSAHDCAEGGLTIALTECCLTGDLGAIIELGDFQIRPDAMLFGESASRVLITISPGDKEKAESVLQESGLKYRNIGKTGGNRLIIDSYIDLELTEIKDRWERTIPCHMK
>NC_011899|2407008:2415563|2414171_2415563_-|WP_143710118.1|DBSCAN-SWA
MMERNIFENICPLDHRYSLKKDLFNDLGKYFSEKATIYFQARVELALVKALAGRGVCSFDVVKEVEEAVKGIKVGEVYEEEARTRHNIRALVNCIRKKISAEARPFVHLSATSFDIVDTANSLRYKEATEKLIVPALERLLEQWLNLAEQERDTLQIGRTHGQHAEPLTFGLVMAYYASRLHERIVNLEKVVSSLCGKMAGAVGAYNASSLFFEDPEEFEKEVLKELGLKPAPVSTQIVPPEYMTDYVHSLITVFGVLADFSDDMRHLQRTEIGETGEYFAKDQVGSSTMPHKRNPINYENVKSMWKTFMPRMVTMYLDQLSEHQRDLTNSASGRFIAEIASGLMMTVDRLYKVSSRMKINSRKMKNNFNLSKNMIIAEPLYIFLAAAGHPDAHEYVRKLTLKADKEGKDLVELIKADKEIETYLAKLDKRQKDILYNPEQYTGIARERTEEIVTKIRKERGL
>NC_011899|2407008:2415563|2413467_2414172_-|WP_015923930.1|DBSCAN-SWA
MLTKLEMLYEGKAKKVYRTEDKDRVIIEYKDDATAFNGKKKGTIQEKGFYNAQISAALFNLLEDNGVKTHFIKKLGDREQLTTYVDIIPLEVVVRNIVAGSLSKRLGLEEGYVLEEPIIEFYYKRDDLGDPLLNNSHIRALKLADEEEIKEITAMGFKVNDILRNYLSNKGIELVDFKLEFGKNNGNILLADEISPDTCRFWDKSSGEKLDKDRFRRDLGGVENAYREVWSRVK
>NC_011899|2407008:2415563|2413056_2413311_-|WP_015923929.1|DBSCAN-SWA
MRWKIEVKVNLKEGILDPQGSTIEKSLHSLGYKDISKVRVGKDITFFMEGENREDVVKRAEETAGRILANPVIEDYKVEVKKAN
>NC_011899|2407008:2415563|2412334_2413042_-|WP_015923928.1|DBSCAN-SWA
MKFGVIVFPGSNCDRDCYHVTARVLGEPTEFIWHEDDRSLAGYDCIIIPGGFSYGDYLRAGAIARFAPVMERVKEFARKGGLVIGICNGFQILLEAGLLPGAMHHNAHLNFNCRYVYLRVENNKTPFTGKFNKGDIINLPVAHKEGNYYIDDRGLEELKENNQIILRYATPGGEVIDEANPNGSIGNIAGITNKNHNVFGLMPHPERASETILGNGSDDGLKIFQSILKAGGVKL
>NC_011899|2407008:2415563|2407008_2407626_-|WP_015923924.1|DBSCAN-SWA
MGNKINLAVFISGNGTNLQAIIDSIKAGRVEAELKMVISDKKNAYGLVRAEKAGIENIFIDPADFNSRQGYEKELLDYLDKKNIDLVALAGFMRLLSPYFINQFSGKIMNIHPSLLPSFPGLHAQRQALEYGVKVSGCTVHFVDEGMDTGPIILQAPVPVYSDDTEERLASRIREKEHELYPEAIQLFAENRLTIQGRKVYINQP
>NC_011899|2407008:2415563|2408709_2410152_-|WP_015923926.1|DBSCAN-SWA
MPYEIMSGKPREECGVFGIFSPDRNDAGSLIYLGLHSLQHRGQESAGIAVSQDKGINLYKRMGLVDNVFNKSIIETLSGWAGIGHVRYSTTGSSLAANSQPILINSIKGQVALAHNGNLVNGYELRIALEKKGSVFHSTLDTEVIAHLIARSQYNDIPSALLDSLKTIEGAYSLVVLTRDKLIGVRDPRGFRPLVMGKLGEGIVLASETCALNIIGAEYVRDIEPGEMVVIDENGVQSYSFNPEVEPRFCIFEYIYFARPDSSFNGNNVHLIRKDMGRQLAREAGDLLKKIDVVVPVPDSGISSAQGFAEESGLPFQYGLIKNRYVGRTFINPTQEMRNLKVRMKLNPIKNIIRGKNIALIDDSIVRGTTSRQIVNMLKEAGARDVHLFVSSPPVTHSCYYGLDTSNRQELIASRLNVKDIAREIGADSLTYLSIEGLLSTVERKEKGCCVACFSGDYPTRTGNGKLALEKNVPEIKSGQ
>NC_011899|2407008:2415563|2407615_2408668_-|WP_015923925.1|DBSCAN-SWA
MKKGITYADSGVNIDKGNEFVDRIKDKVKETHLPGVIGGVGGFGGLFAPDFKQYQKPVLVSGTDGVGTKLKIAQLVNKHDIIGIDLVAMCVNDILAQGAKPLFFLDYMATGQLELETGEEIITGITRGCKQAGVALLGGETAEMPGFYQQGSYDLAGFAVGIVDRKNIITGSKIKAGDQLLGLPSSGIHSNGYSLVRKVLLEKEGLKVDDRIKELDCTLGEELLKPTRIYVPVVLPLLEKYEVKGIAHITGGGMPENIARIIPDGLQARVNRESWSCPPVFTYIQAKGDIATVEMERTFNMGIGMVLVVSPDILENVMSDIKARGEKVYHIGEINSIGKKEGKVVIYNGQ

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015923924.1|2407008_2407626_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.9e-32	41.2
WP_015923925.1|2407615_2408668_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.1e-76	48.0
WP_015923926.1|2408709_2410152_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.6e-55	33.1
WP_015923927.1|2410136_2412338_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.0e-169	43.4
WP_015923928.1|2412334_2413042_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_015923929.1|2413056_2413311_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_015923930.1|2413467_2414172_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3HI61	Synechococcus_phage	6.8e-46	44.2
WP_143710118.1|2414171_2415563_-	adenylosuccinate lyase	A0A1B1ISB0	uncultured_Mediterranean_phage	7.2e-31	27.8