CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_010321	Thermoanaerobacter pseudethanolicus ATCC 33223, complete sequence	8 crisprs	RT,cas6,cas8b1,cas7,cas5,cas3,cas4,cas1,cas2,csa3,Cas14b_CAS-V-F,csx20,csx1,cas10,csm3gr7,csx19,DEDDh,cmr1gr7,cas14k,cas14j,casR	0	13	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_010321_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010321_1

121655-124892

TypeI-B

Consensus_repeat	Method
GTTTTTAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRT

48 spacers

cas3,cas5,cas7,cas8b1,cas6,cas4,cas1,cas2

The CRISPR arrays of NC_010321_1

>merge|NC_010321|1|121655-124892|PILER-CR,CRISPRCasFinder,CRT
GTTTTTAGCCTACCTATAAGGAATTGAAACAGCTGAAAGACATTTTAAAGTAGCAGGGCAAGGTACAGGTTTTTAGCCTACCTATAAGGAATTGAAACAGTCTATCTTGGCCGACAGGTCTATCCCGATGTAACGGTTTTTAGCCTACCTATAAGGAATTGAAACACAAAAGCGACATGACAATTACTTGCATGAATGGCAAGTTTTTAGCCTACCTATAAGGAATTGAAACGCAACATTGGCAAATGAGCTCAAGACGAAATTTAATGTTTTTAGCCTACCTATAAGGAATTGAAACGGCCGTACCTCGGTCCAGGCGATCCGAGGTTGAGGGTTTTTAGCCTACCTATAAGGAATTGAAACATTTATAATCTACAGATAAAACATAAGTTGTGCCTGGTTTTTAGCCTACCTATAAGGAATTGAAACTGCATTTCCCCACCTTCGCGGTAAAGCTCCACGAACGGTTTTTAGCCTACCTATAAGGAATTGAAACCCAAGAGCGAAGGCAGCGCCAAATGCGCCGGCATTAGTTTTTAGCCTACCTATAAGGAATTGAAACCGAGACCCAGAGCGGCAAGTTTGACATGATCAAGAAGTTTTTAGCCTACCTATAAGGAATTGAAACCGCCGAATTCAGCTGGAAGCATGGGGAGTGGAAGGAGGTTTTTAGCCTACCTATAAGGAATTGAAACATACTATCACGGCATAAGGCACAAAAGATTGTTTATATGTTTTTAGCCTACCTATAAGGAATTGAAACAAGTATAATCAAAGCGGATGTGCTGACCCAACAGTTTGTTTTTAGCCTACCTATAAGGAATTGAAACACGTATAGCTTCAAACTGGCCGTAATTATAGGCAAAGTTTTTAGCCTACCTATAAGGAATTGAAACATTTTCGACGATATACAGAAACCCACAACAATCCAGAGGTTTTTAGCCTACCTATAAGGAATTGAAACATTTATTGACATGCGGCATATTCGGATTTGGATGGCGTTTTTAGCCTACCTATAAGGAATTGAAACTTTGCTGGTGCTCCAGAATGGTGCGTCCGGTTCTTTGGTTTTTAGCCTACCTATAAGGAATTGAAACTTGACAATAAAATCGCTTTTTCTGTTCAATATCCTATGGTTTTTAGCCTACCTATAAGGAATTGAAACTGCAAAATTTCAGAAAATTTCAGGAAAGGAGGTATGCGGTTTTTAGCCTACCTATAAGGAATTGAAACTGGGATGGTCGGATAAAAAAATTGCTGAACAATTAGGGTTTTTAGCCTACCTATAAGGAATTGAAACAGATACTTTTTAACTTCTTTATATATTTAATAAAAAGTTTTTAGCCTACCTATAAGGAATTGAAACACCGATTCTTGTTCCTGCTGATTGTAGCAACATCAACGTTTTTAGCCTACCTATAAGGAATTGAAACAAACCCGTAGACCGTCATACCGTGAAATCCTCACCGGGTTTTTAGCCTACCTATAAGGAATTGAAACGCCTTTTTGTCTAACACTTGGAATGCTATTAGCACGGTTTTTAGCCTACCTATAAGGAATTGAAACACACAACTGAGGTGACTGTAAGCCGATGGAAGCAAAGGTTTTTAGCCTACCTATAAGGAATTGAAACGTTTAGGCACATCGTTTTCGCAGTTGCCGTTGCTAAGGTTTTTAGCCTACCTATAAGGAATTGAAACTGAGATTAAGGATTATCTTGTTGCTGACTGGGAGTTAGTTTTTAGCCTACCTATAAGGAATTGAAACACTCTTGATACTTGATTGCTTCTCTTTCTGCATTCCAAGTTTTTAGCCTACCTATAAGGAATTGAAACCAGCACTCTTCCACCCCGCCGTTGACTAGTACGTTAAGTTTTTAGCCTACCTATAAGGAATTGAAACTAATGATTGATTCTTCTCTGCCGTCTTTATAAAGCACAGGGTTTTTAGCCTACCTATAAGGAATTGAAACAACAACATATTATCAAAATTATGAAATTTCACAAACGGTTTTTAGCCTACCTATAAGGAATTGAAACACAAGCTCGCCTATCTTTCCACCAGCTGACTGCATGTTTTTAGCCTACCTATAAGGAATTGAAACAATCCTGGCCCCGGGCAAAGACCACTTCTTCATGCTCCGTTTTTAGCCTACCTATAAGGAATTGAAACTGTAAACGAGGGAAAGGATGAAAAAAAAATGATAAAGTTTTTAGCCTACCTATAAGGAATTGAAACTGATATTTAAGCGCGCGATGTGGAGGGGTCTCGTGGGTTTTTAGCCTACCTATAAGGAATTGAAACCGTGCCTGCAGACTGCAATGCCTACGACGTCATGGAGTTTTTAGCCTACCTATAAGGAATTGAAACAGTACTAAAGATTGAGGAGGTATAAACATGGAAGAGGTTTTTAGCCTACCTATAAGGAATTGAAACCAGCCTGTTGCTTATAATTAAGGTAACAGCAGGTTAGGTTTTTAGCCTACCTATAAGGAATTGAAACAGCTGTTCCTGCAAGGATGCGATGGTTGCAGTTTTTTGTTTTTAGCCTACCTATAAGGAATTGAAACCCACCTTTTTTACCTCAATTAGTTCTATAGTATTAAAGGTTTTTAGCCTACCTATAAGGAATTGAAACAAACTAGTGATGGATATGTTGATTGGCTAAGTATTGAGTTTTTAGCCTACCTATAAGGAATTGAAACTTGCTTTAGCAAGATTGTTATTTTTTAACATATTACGTTTTTAGCCTACCTATAAGGAATTGAAACGAAAAGCAGTTGGAGGAGGCAAAAGAACATGAAAAGGTTTTTAGCCTACCTATAAGGAATTGAAACCAGTATTGAAACATTAAAAAATAATGCAGAGCTGAAGGTTTTTAGCCTACCTATAAGGAATTGAAACCCTGTAGCACCTTTGTAGTTATCTAAAACCTCAATGGGTTTTTAGCCTACCTATAAGGAATTGAAACTAATATCCTGAAACAAAGAAAAAACGCTGAATCTCAGGTTTTTAGCCTACCTATAAGGAATTGAAACTAGAGCCTTTTAATATTGCAAAGGAAAAGGTGCTTTCGGTTTTTAGCCTACCTATAAGGAATTGAAACATCGCTTAAATTGTTCTTCTGTTAATTCATTCTCTGGTTTTTAGCCTACCTATAAGGAATTGAAACAGTATTAAAAATTAAGGAGGTTTAAAAAATGGAAAAGTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|1|1|121655-124760|PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTGAAAGACATTTTAAAGTAGCAGGGCAAGGTACAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTCTATCTTGGCCGACAGGTCTATCCCGATGTAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAAAAGCGACATGACAATTACTTGCATGAATGGCAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCAACATTGGCAAATGAGCTCAAGACGAAATTTAAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GGCCGTACCTCGGTCCAGGCGATCCGAGGTTGAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTTATAATCTACAGATAAAACATAAGTTGTGCCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCATTTCCCCACCTTCGCGGTAAAGCTCCACGAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAAGAGCGAAGGCAGCGCCAAATGCGCCGGCATTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGAGACCCAGAGCGGCAAGTTTGACATGATCAAGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCCGAATTCAGCTGGAAGCATGGGGAGTGGAAGGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATACTATCACGGCATAAGGCACAAAAGATTGTTTATAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGTATAATCAAAGCGGATGTGCTGACCCAACAGTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACGTATAGCTTCAAACTGGCCGTAATTATAGGCAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTTTCGACGATATACAGAAACCCACAACAATCCAGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTTATTGACATGCGGCATATTCGGATTTGGATGGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTGCTGGTGCTCCAGAATGGTGCGTCCGGTTCTTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGACAATAAAATCGCTTTTTCTGTTCAATATCCTATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCAAAATTTCAGAAAATTTCAGGAAAGGAGGTATGCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGGATGGTCGGATAAAAAAATTGCTGAACAATTAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGATACTTTTTAACTTCTTTATATATTTAATAAAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACCGATTCTTGTTCCTGCTGATTGTAGCAACATCAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAACCCGTAGACCGTCATACCGTGAAATCCTCACCGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCCTTTTTGTCTAACACTTGGAATGCTATTAGCACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACACAACTGAGGTGACTGTAAGCCGATGGAAGCAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GTTTAGGCACATCGTTTTCGCAGTTGCCGTTGCTAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGAGATTAAGGATTATCTTGTTGCTGACTGGGAGTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACTCTTGATACTTGATTGCTTCTCTTTCTGCATTCCAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGCACTCTTCCACCCCGCCGTTGACTAGTACGTTAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAATGATTGATTCTTCTCTGCCGTCTTTATAAAGCACAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AACAACATATTATCAAAATTATGAAATTTCACAAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAAGCTCGCCTATCTTTCCACCAGCTGACTGCAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AATCCTGGCCCCGGGCAAAGACCACTTCTTCATGCTCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTAAACGAGGGAAAGGATGAAAAAAAAATGATAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGATATTTAAGCGCGCGATGTGGAGGGGTCTCGTGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGTGCCTGCAGACTGCAATGCCTACGACGTCATGGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTACTAAAGATTGAGGAGGTATAAACATGGAAGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGCCTGTTGCTTATAATTAAGGTAACAGCAGGTTAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTGTTCCTGCAAGGATGCGATGGTTGCAGTTTTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCACCTTTTTTACCTCAATTAGTTCTATAGTATTAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAACTAGTGATGGATATGTTGATTGGCTAAGTATTGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGCTTTAGCAAGATTGTTATTTTTTAACATATTAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GAAAAGCAGTTGGAGGAGGCAAAAGAACATGAAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGTATTGAAACATTAAAAAATAATGCAGAGCTGAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCTGTAGCACCTTTGTAGTTATCTAAAACCTCAATGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAATATCCTGAAACAAAGAAAAAACGCTGAATCTCAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGAGCCTTTTAATATTGCAAAGGAAAAGGTGCTTTCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC

>NC_010321|1|1|121655-124892|CRISPRCasFinder
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTGAAAGACATTTTAAAGTAGCAGGGCAAGGTACAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTCTATCTTGGCCGACAGGTCTATCCCGATGTAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAAAAGCGACATGACAATTACTTGCATGAATGGCAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCAACATTGGCAAATGAGCTCAAGACGAAATTTAAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GGCCGTACCTCGGTCCAGGCGATCCGAGGTTGAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTTATAATCTACAGATAAAACATAAGTTGTGCCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCATTTCCCCACCTTCGCGGTAAAGCTCCACGAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAAGAGCGAAGGCAGCGCCAAATGCGCCGGCATTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGAGACCCAGAGCGGCAAGTTTGACATGATCAAGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCCGAATTCAGCTGGAAGCATGGGGAGTGGAAGGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATACTATCACGGCATAAGGCACAAAAGATTGTTTATAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGTATAATCAAAGCGGATGTGCTGACCCAACAGTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACGTATAGCTTCAAACTGGCCGTAATTATAGGCAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTTTCGACGATATACAGAAACCCACAACAATCCAGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTTATTGACATGCGGCATATTCGGATTTGGATGGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTGCTGGTGCTCCAGAATGGTGCGTCCGGTTCTTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGACAATAAAATCGCTTTTTCTGTTCAATATCCTATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCAAAATTTCAGAAAATTTCAGGAAAGGAGGTATGCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGGATGGTCGGATAAAAAAATTGCTGAACAATTAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGATACTTTTTAACTTCTTTATATATTTAATAAAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACCGATTCTTGTTCCTGCTGATTGTAGCAACATCAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAACCCGTAGACCGTCATACCGTGAAATCCTCACCGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCCTTTTTGTCTAACACTTGGAATGCTATTAGCACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACACAACTGAGGTGACTGTAAGCCGATGGAAGCAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GTTTAGGCACATCGTTTTCGCAGTTGCCGTTGCTAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGAGATTAAGGATTATCTTGTTGCTGACTGGGAGTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACTCTTGATACTTGATTGCTTCTCTTTCTGCATTCCAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGCACTCTTCCACCCCGCCGTTGACTAGTACGTTAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAATGATTGATTCTTCTCTGCCGTCTTTATAAAGCACAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AACAACATATTATCAAAATTATGAAATTTCACAAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAAGCTCGCCTATCTTTCCACCAGCTGACTGCAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AATCCTGGCCCCGGGCAAAGACCACTTCTTCATGCTCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTAAACGAGGGAAAGGATGAAAAAAAAATGATAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGATATTTAAGCGCGCGATGTGGAGGGGTCTCGTGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGTGCCTGCAGACTGCAATGCCTACGACGTCATGGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTACTAAAGATTGAGGAGGTATAAACATGGAAGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGCCTGTTGCTTATAATTAAGGTAACAGCAGGTTAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTGTTCCTGCAAGGATGCGATGGTTGCAGTTTTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCACCTTTTTTACCTCAATTAGTTCTATAGTATTAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAACTAGTGATGGATATGTTGATTGGCTAAGTATTGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGCTTTAGCAAGATTGTTATTTTTTAACATATTAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GAAAAGCAGTTGGAGGAGGCAAAAGAACATGAAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGTATTGAAACATTAAAAAATAATGCAGAGCTGAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCTGTAGCACCTTTGTAGTTATCTAAAACCTCAATGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAATATCCTGAAACAAAGAAAAAACGCTGAATCTCAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGAGCCTTTTAATATTGCAAAGGAAAAGGTGCTTTCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATCGCTTAAATTGTTCTTCTGTTAATTCATTCTCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTATTAAAAATTAAGGAGGTTTAAAAAATGGAAAA
GTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|1|1|121655-124892|CRT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTGAAAGACATTTTAAAGTAGCAGGGCAAGGTACAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTCTATCTTGGCCGACAGGTCTATCCCGATGTAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAAAAGCGACATGACAATTACTTGCATGAATGGCAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCAACATTGGCAAATGAGCTCAAGACGAAATTTAAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GGCCGTACCTCGGTCCAGGCGATCCGAGGTTGAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTTATAATCTACAGATAAAACATAAGTTGTGCCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCATTTCCCCACCTTCGCGGTAAAGCTCCACGAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAAGAGCGAAGGCAGCGCCAAATGCGCCGGCATTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGAGACCCAGAGCGGCAAGTTTGACATGATCAAGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCCGAATTCAGCTGGAAGCATGGGGAGTGGAAGGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATACTATCACGGCATAAGGCACAAAAGATTGTTTATAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGTATAATCAAAGCGGATGTGCTGACCCAACAGTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACGTATAGCTTCAAACTGGCCGTAATTATAGGCAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTTTCGACGATATACAGAAACCCACAACAATCCAGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTTATTGACATGCGGCATATTCGGATTTGGATGGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTGCTGGTGCTCCAGAATGGTGCGTCCGGTTCTTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGACAATAAAATCGCTTTTTCTGTTCAATATCCTATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCAAAATTTCAGAAAATTTCAGGAAAGGAGGTATGCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGGATGGTCGGATAAAAAAATTGCTGAACAATTAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGATACTTTTTAACTTCTTTATATATTTAATAAAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACCGATTCTTGTTCCTGCTGATTGTAGCAACATCAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAACCCGTAGACCGTCATACCGTGAAATCCTCACCGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCCTTTTTGTCTAACACTTGGAATGCTATTAGCACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACACAACTGAGGTGACTGTAAGCCGATGGAAGCAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GTTTAGGCACATCGTTTTCGCAGTTGCCGTTGCTAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGAGATTAAGGATTATCTTGTTGCTGACTGGGAGTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACTCTTGATACTTGATTGCTTCTCTTTCTGCATTCCAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGCACTCTTCCACCCCGCCGTTGACTAGTACGTTAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAATGATTGATTCTTCTCTGCCGTCTTTATAAAGCACAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AACAACATATTATCAAAATTATGAAATTTCACAAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAAGCTCGCCTATCTTTCCACCAGCTGACTGCAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AATCCTGGCCCCGGGCAAAGACCACTTCTTCATGCTCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTAAACGAGGGAAAGGATGAAAAAAAAATGATAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGATATTTAAGCGCGCGATGTGGAGGGGTCTCGTGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGTGCCTGCAGACTGCAATGCCTACGACGTCATGGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTACTAAAGATTGAGGAGGTATAAACATGGAAGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGCCTGTTGCTTATAATTAAGGTAACAGCAGGTTAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTGTTCCTGCAAGGATGCGATGGTTGCAGTTTTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCACCTTTTTTACCTCAATTAGTTCTATAGTATTAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAACTAGTGATGGATATGTTGATTGGCTAAGTATTGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGCTTTAGCAAGATTGTTATTTTTTAACATATTAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GAAAAGCAGTTGGAGGAGGCAAAAGAACATGAAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGTATTGAAACATTAAAAAATAATGCAGAGCTGAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCTGTAGCACCTTTGTAGTTATCTAAAACCTCAATGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAATATCCTGAAACAAAGAAAAAACGCTGAATCTCAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGAGCCTTTTAATATTGCAAAGGAAAAGGTGCTTTCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATCGCTTAAATTGTTCTTCTGTTAATTCATTCTCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTATTAAAAATTAAGGAGGTTTAAAAAATGGAAAA
GTTTTTAGCCTACCTATCCTGAAAATAGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	unknown	unknown	gnl\|CDD\|153240
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268880.1\|113129_114359_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NC_010321.1\|WP_012268877.1\|109903_110650_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|273907
NC_010321.1\|WP_003868738.1\|114355_114769_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268878.1\|110669_112073_+\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_010321.1\|WP_012268879.1\|112083_113133_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|273908

Protein	Function_ID	Function_description	E-value
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	2.8809e-41
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	2.64608e-180
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	gnl\|CDD\|153240	cd03146, GAT1_Peptidase_E, Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. This group contains proteins similar to the aspartyl dipeptidases Salmonella typhimurium peptidase E and Xenopus laevis peptidase E. In bacteria peptidase E is believed to play a role in degrading peptides generated by intracellular protein breakdown or imported into the cell as nutrient sources. Peptidase E uniquely hydrolyses only Asp-X dipeptides (where X is any amino acid), and one tripeptide Asp-Gly-Gly. Peptidase E is believed to be a serine peptidase having a Ser-His-Glu catalytic triad which differs from the Cys-His-Glu catalytic triad typical of GATase1 domains by having a Ser in place of the reactive Cys at the nucleophile elbow. Xenopus PepE is developmentally regulated in response to thyroid hormone and, it is thought to play a role in apoptosis during tail reabsorption.	1.63934e-66
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268880.1\|113129_114359_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_010321.1\|WP_012268877.1\|109903_110650_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|273907	TIGR01978, Probable_ATP-dependent_transporter_SufC, FeS assembly ATPase SufC. SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	7.95469e-138
NC_010321.1\|WP_003868738.1\|114355_114769_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.66901e-73
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.54792e-93
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	8.76406e-41
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	6.26269e-66
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268878.1\|110669_112073_+\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	4.21073e-159
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.16445e-42
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	8.0037e-34
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.27175e-45
NC_010321.1\|WP_012268879.1\|112083_113133_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|273908	TIGR01981, UPF0051_protein_Rv1462/MT1509, FeS assembly protein SufD. This protein, SufD, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. SufB and SufD are homologous. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	2.59693e-75

>NC_010321.1|WP_012268883.1|119117_121472_+|CRISPR-associated-helicase/endonuclease-Cas3
MSSFSELYSHPDKFLEDHLINTSKIIRSYFNEKKVAIIDKETFLKTATIISLCHDFGKATNYFQKYLFTENEKERNKLKTMEEMHHSLLSAVVAFYLVKNEINAQDRKGILFPFIAFLIVKNHHGDLKNVFNEVILDDKELEVLKKQLNSIDDEKLQVLNGKLRNAGLNENLTKSAINDYIDSINSELRKIKRELRRLKEEQDVSIYLLLNFLFSLLVDADKTEVVVGIDNIKRPEIKFEEQLVKEYKASFPDKESKINLLREEAYKEVLEKDIDIKQKIMSINLPTGLGKTLTTIAFAMKLWAKLYKETGVKYRIIYSLPFLSIIEQNSNVLEDLLRYNGIQPDTEIILKHHHLSDIRYTKNNTEFEDEQAKILIEGWNSEIIITTFVQFFHTLVSEKNKTLRKFHRLANSIIILDEVQSIPFKYWLLTKELLKAVANELNSYIIFVTATQPLIFREEEIYPLVAKTKYFTQMDRVEIIPKLSRDITLEELSEMFDLNDGKSYLFILNTIKSAQQFYNILRAKIPNDEIIYMSTHVVPMERMERIEKIKEGKIRFAVTTQLVEAGVDIDFDVVVRDIAPLDSINQSAGRCNRNWRGKGEVYVVSLIDEKGQKYSKYVYDKILLGITREILSKYDTIKEQELLKIIEKYYQEVSERMSSNEGRELLDAIYTLRYDSEDGNMCISKFELIEDDYYKVDAFIELNDEAKELWHKYVELKDIKNLFERRNIFNRFKADFYKYVISIPATVENMPPDIWGFKYVNYDSLNDYYDKETGFITKGVTSIW
>NC_010321.1|WP_003871404.1|118420_119134_+|type-I-B-CRISPR-associated-protein-Cas5
MKTLVFDVFGDYGHFRKYYTTSSPLTFSFPPPPTVKGMLGAIAGIDKKEYLKVFSEENCKVAIRILNPIKKIRLGLNLINTKGNYWIPYKAKNHEARTQVKTEFVKDAAYRIYFMHKDNDLFEDIVEKIKNRRNVYTLSLGLSEMIADYKFIGVYEAEEIENAEVDILSVLPFQSIVEDKIYFENGKKYFKEKIPAGMNEDRVVLSYEDVLYEVNGQSIKCHVKKCWEVKGEHVIFF
>NC_010321.1|WP_012268882.1|117496_118408_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MENVIKNRAEILFLYDVSFANPNGDPVDENKPRIDEETGINIVTDVRLKRTIRDYLAYYKGKEVFIIETRKDNGELRTKKDRIEDFGTNEDIIAKCIDVRLFGATTAVKDKMMILTGPVQFKYGKSLHRVNLMYVKGTTVMPSGEGREQGTFTEKYILPYSLIAFYGIVNENAAINQNIPLTDEDVDLMLEGMWNGTKNLMSGSKIGHMPRLLIEVVYQENNYQIGELEKRIKFVHEMEDEEIRDIQDGKLDITELVAVLKQNQEKIKLIKYIYDDRVTFTCNGEECTLEKALKGLNIQKLQY
>NC_010321.1|WP_012268881.1|115732_117496_+|TIGR02556-family-CRISPR-associated-protein
MITAIKELGEMVLKSQNKTLLDVLIENPNQDGRYSKIIAINFIVKEDEIEYEGIRLEEYDDSKISRYLFTDTGGNAPGYTPAAKITEVPKTFNGKIKNWFNKVLKDKSIKIDEKDRAFLERIKDILEEKSDEIIKEAEKIRGDFPKKEGLSLILKFNVDGEYKYIGDFNVFRDLMLQLDSQKYQKIYAEDKVCSICGQKKDIVFGTVDTYKFYTIDKPGYIAGGFNEKESWKNYPVCAECRLALEEGKRYLENELTFRFYGLEYQLIPNFIIGKEFVRKEVREIFESSERLLSLKREVKKRFIGDEDEILDYLADAEDSMTVNLLFLRKSNSAERILLLIEDVFPSHLREIFNAKEQVDKIFGNSFTFKNIRSFMSKSDSNKRDNDLDGYFLDITDRIFRGRPVDLGFLYNLIMKKIREEFVKDGYYKAATADGLMTIAFLEKMKLIKMEVIPMEERIFDSFFAKYGPTFEMPLKRGLVLLGALTELLLRKQYSDREAKPFMKNLKGLKMDEKDIKGLLPKVQNKLEEYDSFEKGKRLLAKEASNYLLLAGDNWNMSVDEINFYFACGINLADELTSIIYKKEGEEK
>NC_010321.1|WP_004399630.1|114957_115713_+|CRISPR-associated-endoribonuclease-Cas6
MRITLEFVGEKNLVLPIHYNYIVQGFLYDLMGDSEFAAFLHDEGFQYEKRKFKLFTFSRIEGEFKILTDSKGQKKISIKPPFKFTVASPLDEFIFDISKNALKKEYCHFNGQKFILNSLNIDNPPVFKNKARIKFISPVVMYTTLKDGDIKYTYYYSPWDEKFSPLLLNNLLKKYELVYKIKAEDPYFKLYPLSEKEDRRYSKMIKYKNVYVKGWMGIYDVESSPELLELAYYTGLGAKNSQGFGCFEIIG
>NC_010321.1|WP_003868738.1|114355_114769_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MSDLNQLYSEVIMEHYENSPHRRELKDATHKERGHNPLCGDDITLYLKMNGDIIEDASFTGHGCAISQASTSMMIDLIKGKDKKEALRLVQEFIDMIHKKDVNLDELGDAQVLHGVSDFPARVKCALLAWKTLQEIL
>NC_010321.1|WP_012268880.1|113129_114359_+|cysteine-desulfurase
MKNIDIERIKKDFPILSVKPHGKRLVYLDNAATTQKPIEVIKAMDKYYEELNANVYRSPHYLSVLSTQAYEEARERVKKFINAKKEESIVFTRNTTESINFIAYTWGMKHINEGDEILLTIAEHHSNILPWQMVAEAKGAKLKYVYLDENFRLSMKDFKEKMSEKVKLVAVQHMSNVLGIINPVEEITHIAHKYGAKVLIDGAQSVPHMPVDVQKIDCDFFAFSGHKMLGPMGIGVLYIKEDLLKEVPPFLRGGEMIDEVYEDHSTFAPSPLKFEAGTPNIEGAYVLISAIDYIEKIGLTNIYKHEGELLEYGLQKMRELDFVKLYGPKDAKERGGIISFNVEGVHPHDVATILDEEGVAVRSGHHCCQPLMRYLGVPATVRASFYLYNDFEDIDALVEGLKKVRKWFK
>NC_010321.1|WP_012268879.1|112083_113133_+|Fe-S-cluster-assembly-protein-SufD
MWKRVSMEEIQQPSYKEYTSAVIKNLSHDTVKIKETKKLAGLPTEILALRDKAFGIEGKFINMVRDFYNAGFHIEISQNSNVEKPIVIDYITNEQNDTLIDYNIIEAEANSQVTIVFDYNSGTKGFHNGITQVIAKEGSTVNIVKIQRLGDEFNDFDNNLVIVGKNAMVNWSNVVIGSKVSAFDVAVYLDEVGGTFTSKSIFLGVDSQKYDMAYKVYHQAPKTTSSVDLKGALKGSAKATFIGNIDIKKGAKKAKAEENETVLLLDKTVKSVAIPALYCGEDDVQANHSASAGQIDEDKLYYVMSRGFSLEEARLLMVQAILNPVIDLIPYDPVREIIIKGHIGRRIIK
>NC_010321.1|WP_012268878.1|110669_112073_+|Fe-S-cluster-assembly-protein-SufB
MKKPDIKEIDFSIYDVKDNVKYEYQTGKGLSKEVVLEISEQKNEPSWMRDFRLKALEIYQKMPMPTWGVDLSQLDIDSIIAYIRPSAKMQRSWDEVPEEIRRTFERLGIPEAERKALAGVGAQYDSEVVYHNIKESLTQQGVIFEDMDTAVKKYPDIIKEYFMTKNVTPYDHKFVALHAAIWSGGTFVYVPEGVKVEVPLQAYFRMNAPGSGQFEHTLIIADKGSEVHFIEGCSAPQYTVSNLHAGCVELFVNEGARIIYSTIENWSKNTYNLNTKRAIVEKDGIIEWISGSFGSHKTMLYPASILKGEGAKAEYTGVTFAAKGQHLDTGSKMIHLAPHTSSKVLAKSISKDGGISSYRGLLKIGPNAEGAKASVQCEGLMLDDISRSDTMPVIEIENDNVDIGHEAKVGRISDEQIFYLMSRGLSEDDARAMIVRGFVEPIAKALPLEYAVEMNRLIKLELEGAIG
>NC_010321.1|WP_012268877.1|109903_110650_+|Fe-S-cluster-assembly-ATPase-SufC
MRETLLEIKDLHIEVEGKYILKGLNLTIKKGEIHAIMGPNGGGKSTLCNSIMGNPKYKVTSGQILFEGEDITNLKVNERAKKGIFLSFQYPEEIPGITVDNFIRTSVNIVTGQNVSMLQFAKEMKNTLELLDMNSEYRSRYLNVGFSGGEKKKAEILQMAFLKPKLVMLDEIDSGLDIDALKVVAEAVKKLKSEDMSILIVTHYNRILDYLEPDVISVLMDGKIVKSGDKDLAKILEEKGYDFVRNGV
>NC_010321.1|WP_003869923.1|124977_126198_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|128110_129331_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|129769_130990_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|135695_136916_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|138221_139442_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012268884.1|141548_142769_-|IS110-family-transposase
MDLVYSHVCGLDVHKKSVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_009052111.1|142907_143636_+|peptidase-E
MKKVVAIGGGEISKFETFKIDEEIVKLTDKAKPKALFVPTASGEPEAYCDNFDFVYGKMLGCETDILFLIKDDPDSSQIEKKISWADLIYVGGGNTKRMMEIWRSKGVDKMLIDAYQRGTVLSGLSAGAICWFKYGFSDSQRFENQENWHYTKVEGLGLFDAILCPHLNEENRRELFEKFMIDFEGVGIGLENGCAIEIVDDTFKIINSFENAHAYVFRRSENKLFVDEIRHRDYIPFNLLI
>NC_010321.1|WP_003867574.1|143964_144462_+|CRISPR-associated-protein-Cas4
MEFEVTGALMQSYTICKRQVWLMAHQIVPDQEHPYIEIGRLIDENSYQRDRKKIHFENVVLDLVRMEKDNILIGEVKKSSKAEDSAKMQLLFYLYKLKQSGITAKGQLFFPEERKREVVELTPEFEREVIKAIEEIKDIVYKEKPPAFIKIPYCKNCGYKEFCMS
>NC_010321.1|WP_004399636.1|144458_145451_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKTIYIFSDGELKRKDNTLFFEGENGRKFIPVENTSEIMVFGEVSLNKRLLEFLTQSEIILHFFNHYGYYVGSYYPREHLNSGYMILRQAEHYNDESKRLYLAQKFVEGAYKNIRQVLKYYSNRGKDLEDVIYSIEKLGESVDSTSTINELMAIEGNIREYYYKAFDEIIQNPDFKFDFRSKRPPQNFLNTLISFGNSLMYTTTLSEIYKTHLDPRIGFLHATNFRRFSLNLDVSEIFKPIIVDRTIFTLLSKKMVTKEDFEEDAEGLLLKEKGKKVFVQEFEDKLATTIKHRNLSNNVSYRRLIRLELYKLEKHLIEEEQYKPFIAQW
>NC_010321.1|WP_003871087.1|145467_145731_+|CRISPR-associated-endonuclease-Cas2
MFLILVYDVNEKRVNKVLKTCRKYLHWVQNSVLEGEISEANLKKLKIELSRIIDKDEDSVIFYILRTTKYSEREILGLRKGGEDIII

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Crispr_ID: NC_010321_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010321_2

126456-128025

TypeI-B

Consensus_repeat	Method
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder

23 spacers

cas3,cas5,cas7,cas8b1,cas6,cas4,cas1,cas2

The CRISPR arrays of NC_010321_2

>merge|NC_010321|2|126456-128025|CRT,PILER-CR,CRISPRCasFinder
GCGGCATGGGAGTCTATAAGGAATTGAAACCTAATTTGCTTTAAGCTTGTTGCTACAAGATAGACCTTGGTTTTTAGCCTACCTATAAGGAATTGAAACCGCCGAGGTCTTCTCCTGTCGCGATATAATGCGACAGGGTTTTTAGCCTACCTATAAGGAATTGAAACGGCAATAGTTTTATTACGTCCAAAACAAACTAAAAGGTTTTTAGCCTACCTATAAGGAATTGAAACAAAGGGCGGTTAAACTGCCTGAAAACGGCATAGTGGGGTTTTTAGCCTACCTATAAGGAATTGAAACCATGGAAGCAGCAGCCGAGGCCACAGGTGGAGTTTATGGTTTTTAGCCTACCTATAAGGAATTGAAACATGCACCTTGCTTTAGGAGTGCATAAGCCTCTCTCCCGGTTTTTAGCCTACCTATAAGGAATTGAAACTAAAGCAAAAAACCAGTGGCTTTGCTGCAAGGGTTGAGTTTTTAGCCTACCTATAAGGAATTGAAACAGCTGTTGTTTTGACATATTCATCATCCTTTCTGAAGTTTTTAGCCTACCTATAAGGAATTGAAACTGACATTGTCTTCTTTAATTACCTTTCTTATGAAATCCGGTTTTTAGCCTACCTATAAGGAATTGAAACGCAGGCAACCCAAAGCGGATGCATTTATGGATTGGGTTTTTAGCCTACCTATAAGGAATTGAAACATTAAGTTGTTGGGCCATGATATCAGGGGCAATAACGTTTTTAGCCTACCTATAAGGAATTGAAACTAAGAACCTGTCATAATCTTTTCATTCTTATTTCTAGTTTTTAGCCTACCTATAAGGAATTGAAACAAGGAATTTTGGCTAATAAGCTTGAAAACTTCCATCGTTTTTAGCCTACCTATAAGGAATTGAAACCAAAAATTCTGTACTTTATACCGTTGATTTTTTTATGGTTTTTAGCCTACCTATAAGGAATTGAAACTACGCAGTACATACAGCAAAGAAGCAGATATTACAGGGTTTTTAGCCTACCTATAAGGAATTGAAACTAGCACCGGCATCCAGTAATCATCATGGAAATTATGAGGTTTTTAGCCTACCTATAAGGAATTGAAACCCATGACGTGGCGGCATCATTACAATAAGACGATTAAGGTTTTTAGCCTACCTATAAGGAATTGAAACTCTACCGTGACGGGTCGGTGGTCCAGCCGACCGAATAGGTTTTTAGCCTACCTATAAGGAATTGAAACGTCCATCTTTTTATATTAGCCATCATTATCACCTCAACGTTTTTAGCCTACCTATAAGGAATTGAAACTGGATTACGTGGGCATAGAGAACAAGGTTGACGCCAGTTTTTAGCCTACCTATAAGGAATTGAAACCATAGGCCGTGGCTGGGCCGGTATCGGGTATAACGGTTTTTAGCCTACCTATAAGGAATTGAAACGGTATATAAACGTCTACGACAATGATGAAGATGTATGTTTTTAGCCTACCTATAAGGAATTGAAACAGAGGAACAATTGGAATGTATGAAATAGGACAAAGAGTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|2|2|126456-128025|CRT
GCGGCATGGGAGTCTATAAGGAATTGAAAC	CTAATTTGCTTTAAGCTTGTTGCTACAAGATAGACCTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCCGAGGTCTTCTCCTGTCGCGATATAATGCGACAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GGCAATAGTTTTATTACGTCCAAAACAAACTAAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAAGGGCGGTTAAACTGCCTGAAAACGGCATAGTGGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATGGAAGCAGCAGCCGAGGCCACAGGTGGAGTTTATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGCACCTTGCTTTAGGAGTGCATAAGCCTCTCTCCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAAGCAAAAAACCAGTGGCTTTGCTGCAAGGGTTGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTGTTGTTTTGACATATTCATCATCCTTTCTGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGACATTGTCTTCTTTAATTACCTTTCTTATGAAATCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCAGGCAACCCAAAGCGGATGCATTTATGGATTGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTAAGTTGTTGGGCCATGATATCAGGGGCAATAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAGAACCTGTCATAATCTTTTCATTCTTATTTCTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGGAATTTTGGCTAATAAGCTTGAAAACTTCCATC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAAAAATTCTGTACTTTATACCGTTGATTTTTTTATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TACGCAGTACATACAGCAAAGAAGCAGATATTACAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGCACCGGCATCCAGTAATCATCATGGAAATTATGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCATGACGTGGCGGCATCATTACAATAAGACGATTAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCTACCGTGACGGGTCGGTGGTCCAGCCGACCGAATAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GTCCATCTTTTTATATTAGCCATCATTATCACCTCAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGATTACGTGGGCATAGAGAACAAGGTTGACGCCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATAGGCCGTGGCTGGGCCGGTATCGGGTATAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GGTATATAAACGTCTACGACAATGATGAAGATGTAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGAGGAACAATTGGAATGTATGAAATAGGACAAAGA
GTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|2|2|126525-127959|PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCCGAGGTCTTCTCCTGTCGCGATATAATGCGACAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GGCAATAGTTTTATTACGTCCAAAACAAACTAAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAAGGGCGGTTAAACTGCCTGAAAACGGCATAGTGGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATGGAAGCAGCAGCCGAGGCCACAGGTGGAGTTTATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGCACCTTGCTTTAGGAGTGCATAAGCCTCTCTCCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAAGCAAAAAACCAGTGGCTTTGCTGCAAGGGTTGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTGTTGTTTTGACATATTCATCATCCTTTCTGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGACATTGTCTTCTTTAATTACCTTTCTTATGAAATCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCAGGCAACCCAAAGCGGATGCATTTATGGATTGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTAAGTTGTTGGGCCATGATATCAGGGGCAATAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAGAACCTGTCATAATCTTTTCATTCTTATTTCTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGGAATTTTGGCTAATAAGCTTGAAAACTTCCATC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAAAAATTCTGTACTTTATACCGTTGATTTTTTTATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TACGCAGTACATACAGCAAAGAAGCAGATATTACAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGCACCGGCATCCAGTAATCATCATGGAAATTATGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCATGACGTGGCGGCATCATTACAATAAGACGATTAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCTACCGTGACGGGTCGGTGGTCCAGCCGACCGAATAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GTCCATCTTTTTATATTAGCCATCATTATCACCTCAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGATTACGTGGGCATAGAGAACAAGGTTGACGCCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATAGGCCGTGGCTGGGCCGGTATCGGGTATAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GGTATATAAACGTCTACGACAATGATGAAGATGTAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC

>NC_010321|2|2|126525-128025|CRISPRCasFinder
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCCGAGGTCTTCTCCTGTCGCGATATAATGCGACAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GGCAATAGTTTTATTACGTCCAAAACAAACTAAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAAGGGCGGTTAAACTGCCTGAAAACGGCATAGTGGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATGGAAGCAGCAGCCGAGGCCACAGGTGGAGTTTATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGCACCTTGCTTTAGGAGTGCATAAGCCTCTCTCCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAAGCAAAAAACCAGTGGCTTTGCTGCAAGGGTTGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTGTTGTTTTGACATATTCATCATCCTTTCTGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGACATTGTCTTCTTTAATTACCTTTCTTATGAAATCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCAGGCAACCCAAAGCGGATGCATTTATGGATTGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTAAGTTGTTGGGCCATGATATCAGGGGCAATAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAGAACCTGTCATAATCTTTTCATTCTTATTTCTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGGAATTTTGGCTAATAAGCTTGAAAACTTCCATC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAAAAATTCTGTACTTTATACCGTTGATTTTTTTATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TACGCAGTACATACAGCAAAGAAGCAGATATTACAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGCACCGGCATCCAGTAATCATCATGGAAATTATGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCATGACGTGGCGGCATCATTACAATAAGACGATTAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCTACCGTGACGGGTCGGTGGTCCAGCCGACCGAATAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GTCCATCTTTTTATATTAGCCATCATTATCACCTCAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGATTACGTGGGCATAGAGAACAAGGTTGACGCCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATAGGCCGTGGCTGGGCCGGTATCGGGTATAACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GGTATATAAACGTCTACGACAATGATGAAGATGTAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGAGGAACAATTGGAATGTATGAAATAGGACAAAGA
GTTTTTAGCCTACCTATCCTGAAAATAGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	unknown	unknown	gnl\|CDD\|153240
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268880.1\|113129_114359_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NC_010321.1\|WP_003868738.1\|114355_114769_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268878.1\|110669_112073_+\|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl\|CDD\|131035
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_010321.1\|WP_012268885.1\|145851_147777_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274912
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_010321.1\|WP_012268879.1\|112083_113133_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|273908

Protein	Function_ID	Function_description	E-value
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	2.8809e-41
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	2.64608e-180
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	gnl\|CDD\|153240	cd03146, GAT1_Peptidase_E, Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. This group contains proteins similar to the aspartyl dipeptidases Salmonella typhimurium peptidase E and Xenopus laevis peptidase E. In bacteria peptidase E is believed to play a role in degrading peptides generated by intracellular protein breakdown or imported into the cell as nutrient sources. Peptidase E uniquely hydrolyses only Asp-X dipeptides (where X is any amino acid), and one tripeptide Asp-Gly-Gly. Peptidase E is believed to be a serine peptidase having a Ser-His-Glu catalytic triad which differs from the Cys-His-Glu catalytic triad typical of GATase1 domains by having a Ser in place of the reactive Cys at the nucleophile elbow. Xenopus PepE is developmentally regulated in response to thyroid hormone and, it is thought to play a role in apoptosis during tail reabsorption.	1.63934e-66
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268880.1\|113129_114359_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_010321.1\|WP_003868738.1\|114355_114769_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.66901e-73
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.54792e-93
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	8.76406e-41
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	6.26269e-66
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268878.1\|110669_112073_+\|Fe-S-cluster-assembly-protein-SufB	gnl\|CDD\|131035	TIGR01980, UPF0051_protein_slr0074, FeS assembly protein SufB. This protein, SufB, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	4.21073e-159
NC_010321.1\|WP_012268885.1\|145851_147777_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|274912	TIGR03997, NADH:flavin_oxidoreductase, mycofactocin system FadH/OYE family oxidoreductase 2. The yeast protein called old yellow enzyme and FadH from Escherichia coli (2,4-dienoyl CoA reductase) are enzymes with 4Fe-4S, FMN, and FAD prosthetic groups, and interact with NADPH as well as substrate. Members of this related protein family occur in the vicinity of the putative mycofactocin biosynthesis operon in a number of Actinobacteria such as Frankia sp. and Rhodococcus sp., in Pelotomaculum thermopropionicum SI (Firmicutes), and in Geobacter uraniireducens Rf4 (Deltaproteobacteria). The function of this oxidoreductase is unknown.	2.09042e-149
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.16445e-42
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	8.0037e-34
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.27175e-45
NC_010321.1\|WP_012268879.1\|112083_113133_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|273908	TIGR01981, UPF0051_protein_Rv1462/MT1509, FeS assembly protein SufD. This protein, SufD, forms a cytosolic complex SufBCD. This complex enhances the cysteine desulfurase of SufSE. The system, together with SufA, is believed to act in iron-sulfur cluster formation during oxidative stress. SufB and SufD are homologous. Note that SufC belongs to the family of ABC transporter ATP binding proteins, so this protein, encoded by an adjacent gene, has often been annotated as a transporter component. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	2.59693e-75

>NC_010321.1|WP_003869923.1|124977_126198_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012268883.1|119117_121472_+|CRISPR-associated-helicase/endonuclease-Cas3
MSSFSELYSHPDKFLEDHLINTSKIIRSYFNEKKVAIIDKETFLKTATIISLCHDFGKATNYFQKYLFTENEKERNKLKTMEEMHHSLLSAVVAFYLVKNEINAQDRKGILFPFIAFLIVKNHHGDLKNVFNEVILDDKELEVLKKQLNSIDDEKLQVLNGKLRNAGLNENLTKSAINDYIDSINSELRKIKRELRRLKEEQDVSIYLLLNFLFSLLVDADKTEVVVGIDNIKRPEIKFEEQLVKEYKASFPDKESKINLLREEAYKEVLEKDIDIKQKIMSINLPTGLGKTLTTIAFAMKLWAKLYKETGVKYRIIYSLPFLSIIEQNSNVLEDLLRYNGIQPDTEIILKHHHLSDIRYTKNNTEFEDEQAKILIEGWNSEIIITTFVQFFHTLVSEKNKTLRKFHRLANSIIILDEVQSIPFKYWLLTKELLKAVANELNSYIIFVTATQPLIFREEEIYPLVAKTKYFTQMDRVEIIPKLSRDITLEELSEMFDLNDGKSYLFILNTIKSAQQFYNILRAKIPNDEIIYMSTHVVPMERMERIEKIKEGKIRFAVTTQLVEAGVDIDFDVVVRDIAPLDSINQSAGRCNRNWRGKGEVYVVSLIDEKGQKYSKYVYDKILLGITREILSKYDTIKEQELLKIIEKYYQEVSERMSSNEGRELLDAIYTLRYDSEDGNMCISKFELIEDDYYKVDAFIELNDEAKELWHKYVELKDIKNLFERRNIFNRFKADFYKYVISIPATVENMPPDIWGFKYVNYDSLNDYYDKETGFITKGVTSIW
>NC_010321.1|WP_003871404.1|118420_119134_+|type-I-B-CRISPR-associated-protein-Cas5
MKTLVFDVFGDYGHFRKYYTTSSPLTFSFPPPPTVKGMLGAIAGIDKKEYLKVFSEENCKVAIRILNPIKKIRLGLNLINTKGNYWIPYKAKNHEARTQVKTEFVKDAAYRIYFMHKDNDLFEDIVEKIKNRRNVYTLSLGLSEMIADYKFIGVYEAEEIENAEVDILSVLPFQSIVEDKIYFENGKKYFKEKIPAGMNEDRVVLSYEDVLYEVNGQSIKCHVKKCWEVKGEHVIFF
>NC_010321.1|WP_012268882.1|117496_118408_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MENVIKNRAEILFLYDVSFANPNGDPVDENKPRIDEETGINIVTDVRLKRTIRDYLAYYKGKEVFIIETRKDNGELRTKKDRIEDFGTNEDIIAKCIDVRLFGATTAVKDKMMILTGPVQFKYGKSLHRVNLMYVKGTTVMPSGEGREQGTFTEKYILPYSLIAFYGIVNENAAINQNIPLTDEDVDLMLEGMWNGTKNLMSGSKIGHMPRLLIEVVYQENNYQIGELEKRIKFVHEMEDEEIRDIQDGKLDITELVAVLKQNQEKIKLIKYIYDDRVTFTCNGEECTLEKALKGLNIQKLQY
>NC_010321.1|WP_012268881.1|115732_117496_+|TIGR02556-family-CRISPR-associated-protein
MITAIKELGEMVLKSQNKTLLDVLIENPNQDGRYSKIIAINFIVKEDEIEYEGIRLEEYDDSKISRYLFTDTGGNAPGYTPAAKITEVPKTFNGKIKNWFNKVLKDKSIKIDEKDRAFLERIKDILEEKSDEIIKEAEKIRGDFPKKEGLSLILKFNVDGEYKYIGDFNVFRDLMLQLDSQKYQKIYAEDKVCSICGQKKDIVFGTVDTYKFYTIDKPGYIAGGFNEKESWKNYPVCAECRLALEEGKRYLENELTFRFYGLEYQLIPNFIIGKEFVRKEVREIFESSERLLSLKREVKKRFIGDEDEILDYLADAEDSMTVNLLFLRKSNSAERILLLIEDVFPSHLREIFNAKEQVDKIFGNSFTFKNIRSFMSKSDSNKRDNDLDGYFLDITDRIFRGRPVDLGFLYNLIMKKIREEFVKDGYYKAATADGLMTIAFLEKMKLIKMEVIPMEERIFDSFFAKYGPTFEMPLKRGLVLLGALTELLLRKQYSDREAKPFMKNLKGLKMDEKDIKGLLPKVQNKLEEYDSFEKGKRLLAKEASNYLLLAGDNWNMSVDEINFYFACGINLADELTSIIYKKEGEEK
>NC_010321.1|WP_004399630.1|114957_115713_+|CRISPR-associated-endoribonuclease-Cas6
MRITLEFVGEKNLVLPIHYNYIVQGFLYDLMGDSEFAAFLHDEGFQYEKRKFKLFTFSRIEGEFKILTDSKGQKKISIKPPFKFTVASPLDEFIFDISKNALKKEYCHFNGQKFILNSLNIDNPPVFKNKARIKFISPVVMYTTLKDGDIKYTYYYSPWDEKFSPLLLNNLLKKYELVYKIKAEDPYFKLYPLSEKEDRRYSKMIKYKNVYVKGWMGIYDVESSPELLELAYYTGLGAKNSQGFGCFEIIG
>NC_010321.1|WP_003868738.1|114355_114769_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MSDLNQLYSEVIMEHYENSPHRRELKDATHKERGHNPLCGDDITLYLKMNGDIIEDASFTGHGCAISQASTSMMIDLIKGKDKKEALRLVQEFIDMIHKKDVNLDELGDAQVLHGVSDFPARVKCALLAWKTLQEIL
>NC_010321.1|WP_012268880.1|113129_114359_+|cysteine-desulfurase
MKNIDIERIKKDFPILSVKPHGKRLVYLDNAATTQKPIEVIKAMDKYYEELNANVYRSPHYLSVLSTQAYEEARERVKKFINAKKEESIVFTRNTTESINFIAYTWGMKHINEGDEILLTIAEHHSNILPWQMVAEAKGAKLKYVYLDENFRLSMKDFKEKMSEKVKLVAVQHMSNVLGIINPVEEITHIAHKYGAKVLIDGAQSVPHMPVDVQKIDCDFFAFSGHKMLGPMGIGVLYIKEDLLKEVPPFLRGGEMIDEVYEDHSTFAPSPLKFEAGTPNIEGAYVLISAIDYIEKIGLTNIYKHEGELLEYGLQKMRELDFVKLYGPKDAKERGGIISFNVEGVHPHDVATILDEEGVAVRSGHHCCQPLMRYLGVPATVRASFYLYNDFEDIDALVEGLKKVRKWFK
>NC_010321.1|WP_012268879.1|112083_113133_+|Fe-S-cluster-assembly-protein-SufD
MWKRVSMEEIQQPSYKEYTSAVIKNLSHDTVKIKETKKLAGLPTEILALRDKAFGIEGKFINMVRDFYNAGFHIEISQNSNVEKPIVIDYITNEQNDTLIDYNIIEAEANSQVTIVFDYNSGTKGFHNGITQVIAKEGSTVNIVKIQRLGDEFNDFDNNLVIVGKNAMVNWSNVVIGSKVSAFDVAVYLDEVGGTFTSKSIFLGVDSQKYDMAYKVYHQAPKTTSSVDLKGALKGSAKATFIGNIDIKKGAKKAKAEENETVLLLDKTVKSVAIPALYCGEDDVQANHSASAGQIDEDKLYYVMSRGFSLEEARLLMVQAILNPVIDLIPYDPVREIIIKGHIGRRIIK
>NC_010321.1|WP_012268878.1|110669_112073_+|Fe-S-cluster-assembly-protein-SufB
MKKPDIKEIDFSIYDVKDNVKYEYQTGKGLSKEVVLEISEQKNEPSWMRDFRLKALEIYQKMPMPTWGVDLSQLDIDSIIAYIRPSAKMQRSWDEVPEEIRRTFERLGIPEAERKALAGVGAQYDSEVVYHNIKESLTQQGVIFEDMDTAVKKYPDIIKEYFMTKNVTPYDHKFVALHAAIWSGGTFVYVPEGVKVEVPLQAYFRMNAPGSGQFEHTLIIADKGSEVHFIEGCSAPQYTVSNLHAGCVELFVNEGARIIYSTIENWSKNTYNLNTKRAIVEKDGIIEWISGSFGSHKTMLYPASILKGEGAKAEYTGVTFAAKGQHLDTGSKMIHLAPHTSSKVLAKSISKDGGISSYRGLLKIGPNAEGAKASVQCEGLMLDDISRSDTMPVIEIENDNVDIGHEAKVGRISDEQIFYLMSRGLSEDDARAMIVRGFVEPIAKALPLEYAVEMNRLIKLELEGAIG
>NC_010321.1|WP_003869923.1|128110_129331_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|129769_130990_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|135695_136916_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|138221_139442_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012268884.1|141548_142769_-|IS110-family-transposase
MDLVYSHVCGLDVHKKSVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_009052111.1|142907_143636_+|peptidase-E
MKKVVAIGGGEISKFETFKIDEEIVKLTDKAKPKALFVPTASGEPEAYCDNFDFVYGKMLGCETDILFLIKDDPDSSQIEKKISWADLIYVGGGNTKRMMEIWRSKGVDKMLIDAYQRGTVLSGLSAGAICWFKYGFSDSQRFENQENWHYTKVEGLGLFDAILCPHLNEENRRELFEKFMIDFEGVGIGLENGCAIEIVDDTFKIINSFENAHAYVFRRSENKLFVDEIRHRDYIPFNLLI
>NC_010321.1|WP_003867574.1|143964_144462_+|CRISPR-associated-protein-Cas4
MEFEVTGALMQSYTICKRQVWLMAHQIVPDQEHPYIEIGRLIDENSYQRDRKKIHFENVVLDLVRMEKDNILIGEVKKSSKAEDSAKMQLLFYLYKLKQSGITAKGQLFFPEERKREVVELTPEFEREVIKAIEEIKDIVYKEKPPAFIKIPYCKNCGYKEFCMS
>NC_010321.1|WP_004399636.1|144458_145451_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKTIYIFSDGELKRKDNTLFFEGENGRKFIPVENTSEIMVFGEVSLNKRLLEFLTQSEIILHFFNHYGYYVGSYYPREHLNSGYMILRQAEHYNDESKRLYLAQKFVEGAYKNIRQVLKYYSNRGKDLEDVIYSIEKLGESVDSTSTINELMAIEGNIREYYYKAFDEIIQNPDFKFDFRSKRPPQNFLNTLISFGNSLMYTTTLSEIYKTHLDPRIGFLHATNFRRFSLNLDVSEIFKPIIVDRTIFTLLSKKMVTKEDFEEDAEGLLLKEKGKKVFVQEFEDKLATTIKHRNLSNNVSYRRLIRLELYKLEKHLIEEEQYKPFIAQW
>NC_010321.1|WP_003871087.1|145467_145731_+|CRISPR-associated-endonuclease-Cas2
MFLILVYDVNEKRVNKVLKTCRKYLHWVQNSVLEGEISEANLKKLKIELSRIIDKDEDSVIFYILRTTKYSEREILGLRKGGEDIII
>NC_010321.1|WP_012268885.1|145851_147777_+|FAD-dependent-oxidoreductase
MELTKPIKIGNLSLKNRVVMAPVKTGYATPEGQVTEELIQYYVNRAKGGVGLIVLESAYVDLSGKEIPRQLGIYDDSMVEGLRRLITPLQEAGSKVAVYINHAGRIANPMVTKLPLIAPSSIACPTIGVEPQGIPHEDIKKWQNTYVKAAVRAYEAGADALEIQFGHGYLIHQFLSPHTNKREDEYGGSFENRIRFGMEILDEIKKEIGADFPIIVRISADEFVPGGWALEDAIRLAKILEDKGVAAIDVSLGSSCESGAITLQTLGTQKGLAWEFASKIKKQVNIPVIAVGRINTPELAEEILVSGKADLVALGRPLVADPLFVEKATSGRSKEIRRCAACHQGCLDELRAGRRFGCNFNPSVGKEEEIEIQKAPQPGKKVFIIGAGLAGLEAAYTAAARGHKVYIYEEKGEIGGQVLPGSVPPHKEELKGIVEYYKEVLPKVGVTLNLNHKVTAEEIAKWEADEVVFATGGQPIVPPIPGLKEYGFLTAVEVLRGEKQAGDKVAIIGGGLIGMETADYLSEQGKKVMVIELLEEVARDMGVFEKILIMKRLKERGVEIYVKTRLKEVGKALLVETPEGEKELPLPDTIVLAVGLKPDPSLYEEVSKILPQEKLHVIGDAKEVRKIVHAISEGRNLGLSL

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Crispr_ID: NC_010321_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010321_3

131248-134493

TypeI-B

Consensus_repeat	Method
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder

48 spacers

cas3,cas5,cas7,cas8b1,cas6,cas4,cas1,cas2,RT

The CRISPR arrays of NC_010321_3

>merge|NC_010321|3|131248-134493|CRT,PILER-CR,CRISPRCasFinder
GCGGCATGGGAGTCTATAAGGAATTGAAACAGGTCAAACCTGGGGCAAAGACTTACGACGGGAAAGTTTTTAGCCTACCTATAAGGAATTGAAACTGCCATCACCTATCATACTATCTCCATCCACTCTTAGTTTTTAGCCTACCTATAAGGAATTGAAACCCATCTCAGACCGTGCAGAAAGCAACTTGTCTAATTGGTTTTTAGCCTACCTATAAGGAATTGAAACAACTATGACATATAAAATTTAATGTGCCTTGTGGAGGTTTTTAGCCTACCTATAAGGAATTGAAACCCAGTACCGTAGCTTCCTACAAATATGATGCCTACTCGTTTTTAGCCTACCTATAAGGAATTGAAACTTTCCCTCTATATATTCAACAGGTTCAGGATATTTACGGTTTTTAGCCTACCTATAAGGAATTGAAACTTGAAAGTAAATTAGGAGAAAGATTTCGTGCAAGAAGGTTTTTAGCCTACCTATAAGGAATTGAAACCGTGTTCCCAAAAAAGTGGACATGGTTCTTGTTCTTCGTTTTTAGCCTACCTATAAGGAATTGAAACATTATTTGCTCAATAGCCGAGCAGAGAACGGATTTGCCTGTTTTTAGCCTACCTATAAGGAATTGAAACTTTCCTCTCGGACCGCCCCATCCATTACAGCAGCCGGTTTTTAGCCTACCTATAAGGAATTGAAACCATGCTCTCTCTGTAGTTGTGCGGCTGTTCCCGGTGGGGTTTTTAGCCTACCTATAAGGAATTGAAACTCTACCAATGCATGGACGATATGCAGGACACCTGGGTTTTTAGCCTACCTATAAGGAATTGAAACGCGAACCCATACTGCAAAGCCTCTTCTGCTGTCATCGTTTTTAGCCTACCTATAAGGAATTGAAACATGCTTCCATCTTTTTTCGCCTCCTCAGTATCTTTCCGTTTTTAGCCTACCTATAAGGAATTGAAACACAATAAGGCGATCCCGGCGCTGATTGATTTAAACGGGTTTTTAGCCTACCTATAAGGAATTGAAACGTTAATACGGCCGGCATGTTTGTCTTGCGAAGCACGGTTTTTAGCCTACCTATAAGGAATTGAAACCCTCGGACGATGCTAAAGCAACTCTTTCACCTTGCAGGTTTTTAGCCTACCTATAAGGAATTGAAACCAGAAAAGTGTATCATTGTGTATCATGTTTCTTGAGTTTGGTTTTTAGCCTACCTATAAGGAATTGAAACCACATTTCAGCAATTCTCGATACTATTGCATCGCCTGGTTTTTAGCCTACCTATAAGGAATTGAAACGAAGAAGAGGAATAGAGAGGGTTTACTCCCTCTCTTCGTTTTTAGCCTACCTATAAGGAATTGAAACTTTTGTCCGAGGGACTTGGTCTAAACGTGGACAGCGAGTTTTTAGCCTACCTATAAGGAATTGAAACAGATCTTTTTGAGGACAATTACCTTTCCGTCTATATGTTTTTAGCCTACCTATAAGGAATTGAAACTGTGTATTACATTGCCTTGTTTATCAAGTGGTTGTATAGTTTTTAGCCTACCTATAAGGAATTGAAACTTACGTGCGCAAAGATGGCAGCATCTTCCGAGGCAGAGGTTTTTAGCCTACCTATAAGGAATTGAAACTTTTATTTCCTCCTCCTTAATTTTTTTATTTTCCCGTTTTTAGCCTACCTATAAGGAATTGAAACTTTTCTATTGCCCACTCCGAAAGCATTGCTTTTCCCGGTTTTTAGCCTACCTATAAGGAATTGAAACTTTTATCGGACTTTGTGATATAATATAAGTATGATATGGTTTTTAGCCTACCTATAAGGAATTGAAACTCCAACCATCCGTTGTGTAACGGATTGGATAACCTTCGTTTTTAGCCTACCTATAAGGAATTGAAACATCCTTTGAGGAAAGTTGTTGAGCTATTGACTTATAGGTTTTTAGCCTACCTATAAGGAATTGAAACTATAGCTGCTCTTGTTTTAAACGTTCTTCCTAACAGTGTTTTTAGCCTACCTATAAGGAATTGAAACCCCCATTTAATGTAGTATCCGTTTTTGTAAATCTTCGTTTTTAGCCTACCTATAAGGAATTGAAACAGAAATTTCTCATCTTCTCTGGAACATCCAAAGCTGCGGTTTTTAGCCTACCTATAAGGAATTGAAACAAGGCAAATACAGGATTGCTTATGGAAAGATTGAGCAGGTTTTTAGCCTACCTATAAGGAATTGAAACTAGAAAGAGCAGAGGGCTAATGCCCTCTCTCTAAAAAAGGTTTTTAGCCTACCTATAAGGAATTGAAACTTTTTAAGATTTTCTGTTTTATCTTTTATCTTGTCTAGTTTTTAGCCTACCTATAAGGAATTGAAACGCCGCTAATTTGTGCTCTTCAGCTTTGAGCTCATTAAGGTTTTTAGCCTACCTATAAGGAATTGAAACTAAAGTCGCGATACTATAGCCTCTGCTGTTTCAACGTGTTTTTAGCCTACCTATAAGGAATTGAAACAAAGCCTCTAATGCACCTTTGAATCCCTTCATTTTGGTTTTTAGCCTACCTATAAGGAATTGAAACCTGTGATACTGTTGCCGCTTACTGCGGTTATGGTCAGTTTTTAGCCTACCTATAAGGAATTGAAACAGTATATAAAGAAGGTTTTGGAAGTTTCTAATTTAGGGTTTTTAGCCTACCTATAAGGAATTGAAACTTGGTTGTGATAATTCAGCTAACTTCTTTTTTGCTGGTTTTTAGCCTACCTATAAGGAATTGAAACAGCAGCCTGTGAAGCTCTGATATAAATTTGTCTTGTGTTTTTAGCCTACCTATAAGGAATTGAAACAGCTAAAACTACCCGATATGCTAAAATGCGGTAATGGTTTTTAGCCTACCTATAAGGAATTGAAACAGCTTTGTTGAAAATTCTTGTACCAATGCTGGAAGGTTTTTAGCCTACCTATAAGGAATTGAAACCGCAAGATGTGGAAGATTTAGAGGATATCGAAGGAACAGTTTTTAGCCTACCTATAAGGAATTGAAACCAGAGCCAGGGAAATTGGATGTAGGCAGGATGCCTGCGTTTTTAGCCTACCTATAAGGAATTGAAACCACTTACGCGCATGCGGTAGCTCCTGATCATGTTCCGGTTTTTAGCCTACCTATAAGGAATTGAAACATATCTTTTCAGCTTCAGCAACAGGATCGAAAGCATAAGGGTTTTTAGCCTCCTTTTTTAAAATTTGAACG

>NC_010321|3|3|131248-134492|CRT
GCGGCATGGGAGTCTATAAGGAATTGAAAC	AGGTCAAACCTGGGGCAAAGACTTACGACGGGAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCCATCACCTATCATACTATCTCCATCCACTCTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCATCTCAGACCGTGCAGAAAGCAACTTGTCTAATTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AACTATGACATATAAAATTTAATGTGCCTTGTGGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAGTACCGTAGCTTCCTACAAATATGATGCCTACTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTCCCTCTATATATTCAACAGGTTCAGGATATTTACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGAAAGTAAATTAGGAGAAAGATTTCGTGCAAGAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGTGTTCCCAAAAAAGTGGACATGGTTCTTGTTCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTATTTGCTCAATAGCCGAGCAGAGAACGGATTTGCCT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTCCTCTCGGACCGCCCCATCCATTACAGCAGCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATGCTCTCTCTGTAGTTGTGCGGCTGTTCCCGGTGGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCTACCAATGCATGGACGATATGCAGGACACCTGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCGAACCCATACTGCAAAGCCTCTTCTGCTGTCATC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGCTTCCATCTTTTTTCGCCTCCTCAGTATCTTTCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAATAAGGCGATCCCGGCGCTGATTGATTTAAACGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GTTAATACGGCCGGCATGTTTGTCTTGCGAAGCACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCTCGGACGATGCTAAAGCAACTCTTTCACCTTGCAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGAAAAGTGTATCATTGTGTATCATGTTTCTTGAGTTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CACATTTCAGCAATTCTCGATACTATTGCATCGCCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GAAGAAGAGGAATAGAGAGGGTTTACTCCCTCTCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTGTCCGAGGGACTTGGTCTAAACGTGGACAGCGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGATCTTTTTGAGGACAATTACCTTTCCGTCTATAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTGTATTACATTGCCTTGTTTATCAAGTGGTTGTATA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTACGTGCGCAAAGATGGCAGCATCTTCCGAGGCAGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTATTTCCTCCTCCTTAATTTTTTTATTTTCCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTCTATTGCCCACTCCGAAAGCATTGCTTTTCCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTATCGGACTTTGTGATATAATATAAGTATGATATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCCAACCATCCGTTGTGTAACGGATTGGATAACCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATCCTTTGAGGAAAGTTGTTGAGCTATTGACTTATAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TATAGCTGCTCTTGTTTTAAACGTTCTTCCTAACAGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCCCATTTAATGTAGTATCCGTTTTTGTAAATCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGAAATTTCTCATCTTCTCTGGAACATCCAAAGCTGCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGGCAAATACAGGATTGCTTATGGAAAGATTGAGCAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGAAAGAGCAGAGGGCTAATGCCCTCTCTCTAAAAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTTAAGATTTTCTGTTTTATCTTTTATCTTGTCTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCCGCTAATTTGTGCTCTTCAGCTTTGAGCTCATTAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAAGTCGCGATACTATAGCCTCTGCTGTTTCAACGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAAGCCTCTAATGCACCTTTGAATCCCTTCATTTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CTGTGATACTGTTGCCGCTTACTGCGGTTATGGTCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTATATAAAGAAGGTTTTGGAAGTTTCTAATTTAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGGTTGTGATAATTCAGCTAACTTCTTTTTTGCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCAGCCTGTGAAGCTCTGATATAAATTTGTCTTGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTAAAACTACCCGATATGCTAAAATGCGGTAATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTTTGTTGAAAATTCTTGTACCAATGCTGGAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCAAGATGTGGAAGATTTAGAGGATATCGAAGGAACA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGAGCCAGGGAAATTGGATGTAGGCAGGATGCCTGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CACTTACGCGCATGCGGTAGCTCCTGATCATGTTCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATATCTTTTCAGCTTCAGCAACAGGATCGAAAGCATAAGG
GTTTTTAGCCTCCTTTTTTAAAATTTGAAC

>NC_010321|3|3|131313-134355|PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCCATCACCTATCATACTATCTCCATCCACTCTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCATCTCAGACCGTGCAGAAAGCAACTTGTCTAATTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AACTATGACATATAAAATTTAATGTGCCTTGTGGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAGTACCGTAGCTTCCTACAAATATGATGCCTACTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTCCCTCTATATATTCAACAGGTTCAGGATATTTACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGAAAGTAAATTAGGAGAAAGATTTCGTGCAAGAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGTGTTCCCAAAAAAGTGGACATGGTTCTTGTTCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTATTTGCTCAATAGCCGAGCAGAGAACGGATTTGCCT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTCCTCTCGGACCGCCCCATCCATTACAGCAGCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATGCTCTCTCTGTAGTTGTGCGGCTGTTCCCGGTGGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCTACCAATGCATGGACGATATGCAGGACACCTGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCGAACCCATACTGCAAAGCCTCTTCTGCTGTCATC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGCTTCCATCTTTTTTCGCCTCCTCAGTATCTTTCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAATAAGGCGATCCCGGCGCTGATTGATTTAAACGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GTTAATACGGCCGGCATGTTTGTCTTGCGAAGCACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCTCGGACGATGCTAAAGCAACTCTTTCACCTTGCAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGAAAAGTGTATCATTGTGTATCATGTTTCTTGAGTTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CACATTTCAGCAATTCTCGATACTATTGCATCGCCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GAAGAAGAGGAATAGAGAGGGTTTACTCCCTCTCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTGTCCGAGGGACTTGGTCTAAACGTGGACAGCGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGATCTTTTTGAGGACAATTACCTTTCCGTCTATAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTGTATTACATTGCCTTGTTTATCAAGTGGTTGTATA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTACGTGCGCAAAGATGGCAGCATCTTCCGAGGCAGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTATTTCCTCCTCCTTAATTTTTTTATTTTCCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTCTATTGCCCACTCCGAAAGCATTGCTTTTCCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTATCGGACTTTGTGATATAATATAAGTATGATATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCCAACCATCCGTTGTGTAACGGATTGGATAACCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATCCTTTGAGGAAAGTTGTTGAGCTATTGACTTATAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TATAGCTGCTCTTGTTTTAAACGTTCTTCCTAACAGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCCCATTTAATGTAGTATCCGTTTTTGTAAATCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGAAATTTCTCATCTTCTCTGGAACATCCAAAGCTGCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGGCAAATACAGGATTGCTTATGGAAAGATTGAGCAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGAAAGAGCAGAGGGCTAATGCCCTCTCTCTAAAAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTTAAGATTTTCTGTTTTATCTTTTATCTTGTCTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCCGCTAATTTGTGCTCTTCAGCTTTGAGCTCATTAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAAGTCGCGATACTATAGCCTCTGCTGTTTCAACGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAAGCCTCTAATGCACCTTTGAATCCCTTCATTTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CTGTGATACTGTTGCCGCTTACTGCGGTTATGGTCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTATATAAAGAAGGTTTTGGAAGTTTCTAATTTAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGGTTGTGATAATTCAGCTAACTTCTTTTTTGCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCAGCCTGTGAAGCTCTGATATAAATTTGTCTTGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTAAAACTACCCGATATGCTAAAATGCGGTAATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTTTGTTGAAAATTCTTGTACCAATGCTGGAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCAAGATGTGGAAGATTTAGAGGATATCGAAGGAACA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGAGCCAGGGAAATTGGATGTAGGCAGGATGCCTGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC

>NC_010321|3|3|131313-134493|CRISPRCasFinder
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCCATCACCTATCATACTATCTCCATCCACTCTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCATCTCAGACCGTGCAGAAAGCAACTTGTCTAATTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AACTATGACATATAAAATTTAATGTGCCTTGTGGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAGTACCGTAGCTTCCTACAAATATGATGCCTACTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTCCCTCTATATATTCAACAGGTTCAGGATATTTACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGAAAGTAAATTAGGAGAAAGATTTCGTGCAAGAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGTGTTCCCAAAAAAGTGGACATGGTTCTTGTTCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTATTTGCTCAATAGCCGAGCAGAGAACGGATTTGCCT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTCCTCTCGGACCGCCCCATCCATTACAGCAGCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATGCTCTCTCTGTAGTTGTGCGGCTGTTCCCGGTGGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCTACCAATGCATGGACGATATGCAGGACACCTGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCGAACCCATACTGCAAAGCCTCTTCTGCTGTCATC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGCTTCCATCTTTTTTCGCCTCCTCAGTATCTTTCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAATAAGGCGATCCCGGCGCTGATTGATTTAAACGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GTTAATACGGCCGGCATGTTTGTCTTGCGAAGCACG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCTCGGACGATGCTAAAGCAACTCTTTCACCTTGCAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGAAAAGTGTATCATTGTGTATCATGTTTCTTGAGTTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CACATTTCAGCAATTCTCGATACTATTGCATCGCCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GAAGAAGAGGAATAGAGAGGGTTTACTCCCTCTCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTGTCCGAGGGACTTGGTCTAAACGTGGACAGCGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGATCTTTTTGAGGACAATTACCTTTCCGTCTATAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTGTATTACATTGCCTTGTTTATCAAGTGGTTGTATA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTACGTGCGCAAAGATGGCAGCATCTTCCGAGGCAGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTATTTCCTCCTCCTTAATTTTTTTATTTTCCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTCTATTGCCCACTCCGAAAGCATTGCTTTTCCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTATCGGACTTTGTGATATAATATAAGTATGATATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCCAACCATCCGTTGTGTAACGGATTGGATAACCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATCCTTTGAGGAAAGTTGTTGAGCTATTGACTTATAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TATAGCTGCTCTTGTTTTAAACGTTCTTCCTAACAGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCCCATTTAATGTAGTATCCGTTTTTGTAAATCTTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGAAATTTCTCATCTTCTCTGGAACATCCAAAGCTGCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGGCAAATACAGGATTGCTTATGGAAAGATTGAGCAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGAAAGAGCAGAGGGCTAATGCCCTCTCTCTAAAAAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTTTAAGATTTTCTGTTTTATCTTTTATCTTGTCTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCCGCTAATTTGTGCTCTTCAGCTTTGAGCTCATTAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAAGTCGCGATACTATAGCCTCTGCTGTTTCAACGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAAGCCTCTAATGCACCTTTGAATCCCTTCATTTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CTGTGATACTGTTGCCGCTTACTGCGGTTATGGTCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTATATAAAGAAGGTTTTGGAAGTTTCTAATTTAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGGTTGTGATAATTCAGCTAACTTCTTTTTTGCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCAGCCTGTGAAGCTCTGATATAAATTTGTCTTGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTAAAACTACCCGATATGCTAAAATGCGGTAATG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTTTGTTGAAAATTCTTGTACCAATGCTGGAAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCAAGATGTGGAAGATTTAGAGGATATCGAAGGAACA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAGAGCCAGGGAAATTGGATGTAGGCAGGATGCCTGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CACTTACGCGCATGCGGTAGCTCCTGATCATGTTCCG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATATCTTTTCAGCTTCAGCAACAGGATCGAAAGCATAAGG
GTTTTTAGCCTCCTTTTTTAAAATTTGAACG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	unknown	unknown	gnl\|CDD\|153240
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268880.1\|113129_114359_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NC_010321.1\|WP_003868738.1\|114355_114769_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NC_010321.1\|WP_012268886.1\|149271_150684_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003871085.1\|148037_148817_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293819
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_010321.1\|WP_012268885.1\|145851_147777_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274912

Protein	Function_ID	Function_description	E-value
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	2.8809e-41
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	2.64608e-180
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	gnl\|CDD\|153240	cd03146, GAT1_Peptidase_E, Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. This group contains proteins similar to the aspartyl dipeptidases Salmonella typhimurium peptidase E and Xenopus laevis peptidase E. In bacteria peptidase E is believed to play a role in degrading peptides generated by intracellular protein breakdown or imported into the cell as nutrient sources. Peptidase E uniquely hydrolyses only Asp-X dipeptides (where X is any amino acid), and one tripeptide Asp-Gly-Gly. Peptidase E is believed to be a serine peptidase having a Ser-His-Glu catalytic triad which differs from the Cys-His-Glu catalytic triad typical of GATase1 domains by having a Ser in place of the reactive Cys at the nucleophile elbow. Xenopus PepE is developmentally regulated in response to thyroid hormone and, it is thought to play a role in apoptosis during tail reabsorption.	1.63934e-66
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268880.1\|113129_114359_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_010321.1\|WP_003868738.1\|114355_114769_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.66901e-73
NC_010321.1\|WP_012268886.1\|149271_150684_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	0
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.54792e-93
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	8.76406e-41
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	6.26269e-66
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003871085.1\|148037_148817_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293819	cd07733, YycJ-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis YycJ and related proteins; MBL-fold metallo hydrolase domain. Includes the uncharacterized Bacillus subtilis YycJ protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.17177e-57
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	4.21073e-159
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.16445e-42
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	8.0037e-34
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.27175e-45
NC_010321.1\|WP_012268885.1\|145851_147777_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|274912	TIGR03997, NADH:flavin_oxidoreductase, mycofactocin system FadH/OYE family oxidoreductase 2. The yeast protein called old yellow enzyme and FadH from Escherichia coli (2,4-dienoyl CoA reductase) are enzymes with 4Fe-4S, FMN, and FAD prosthetic groups, and interact with NADPH as well as substrate. Members of this related protein family occur in the vicinity of the putative mycofactocin biosynthesis operon in a number of Actinobacteria such as Frankia sp. and Rhodococcus sp., in Pelotomaculum thermopropionicum SI (Firmicutes), and in Geobacter uraniireducens Rf4 (Deltaproteobacteria). The function of this oxidoreductase is unknown.	2.09042e-149

>NC_010321.1|WP_003869923.1|129769_130990_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|128110_129331_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|124977_126198_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012268883.1|119117_121472_+|CRISPR-associated-helicase/endonuclease-Cas3
MSSFSELYSHPDKFLEDHLINTSKIIRSYFNEKKVAIIDKETFLKTATIISLCHDFGKATNYFQKYLFTENEKERNKLKTMEEMHHSLLSAVVAFYLVKNEINAQDRKGILFPFIAFLIVKNHHGDLKNVFNEVILDDKELEVLKKQLNSIDDEKLQVLNGKLRNAGLNENLTKSAINDYIDSINSELRKIKRELRRLKEEQDVSIYLLLNFLFSLLVDADKTEVVVGIDNIKRPEIKFEEQLVKEYKASFPDKESKINLLREEAYKEVLEKDIDIKQKIMSINLPTGLGKTLTTIAFAMKLWAKLYKETGVKYRIIYSLPFLSIIEQNSNVLEDLLRYNGIQPDTEIILKHHHLSDIRYTKNNTEFEDEQAKILIEGWNSEIIITTFVQFFHTLVSEKNKTLRKFHRLANSIIILDEVQSIPFKYWLLTKELLKAVANELNSYIIFVTATQPLIFREEEIYPLVAKTKYFTQMDRVEIIPKLSRDITLEELSEMFDLNDGKSYLFILNTIKSAQQFYNILRAKIPNDEIIYMSTHVVPMERMERIEKIKEGKIRFAVTTQLVEAGVDIDFDVVVRDIAPLDSINQSAGRCNRNWRGKGEVYVVSLIDEKGQKYSKYVYDKILLGITREILSKYDTIKEQELLKIIEKYYQEVSERMSSNEGRELLDAIYTLRYDSEDGNMCISKFELIEDDYYKVDAFIELNDEAKELWHKYVELKDIKNLFERRNIFNRFKADFYKYVISIPATVENMPPDIWGFKYVNYDSLNDYYDKETGFITKGVTSIW
>NC_010321.1|WP_003871404.1|118420_119134_+|type-I-B-CRISPR-associated-protein-Cas5
MKTLVFDVFGDYGHFRKYYTTSSPLTFSFPPPPTVKGMLGAIAGIDKKEYLKVFSEENCKVAIRILNPIKKIRLGLNLINTKGNYWIPYKAKNHEARTQVKTEFVKDAAYRIYFMHKDNDLFEDIVEKIKNRRNVYTLSLGLSEMIADYKFIGVYEAEEIENAEVDILSVLPFQSIVEDKIYFENGKKYFKEKIPAGMNEDRVVLSYEDVLYEVNGQSIKCHVKKCWEVKGEHVIFF
>NC_010321.1|WP_012268882.1|117496_118408_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MENVIKNRAEILFLYDVSFANPNGDPVDENKPRIDEETGINIVTDVRLKRTIRDYLAYYKGKEVFIIETRKDNGELRTKKDRIEDFGTNEDIIAKCIDVRLFGATTAVKDKMMILTGPVQFKYGKSLHRVNLMYVKGTTVMPSGEGREQGTFTEKYILPYSLIAFYGIVNENAAINQNIPLTDEDVDLMLEGMWNGTKNLMSGSKIGHMPRLLIEVVYQENNYQIGELEKRIKFVHEMEDEEIRDIQDGKLDITELVAVLKQNQEKIKLIKYIYDDRVTFTCNGEECTLEKALKGLNIQKLQY
>NC_010321.1|WP_012268881.1|115732_117496_+|TIGR02556-family-CRISPR-associated-protein
MITAIKELGEMVLKSQNKTLLDVLIENPNQDGRYSKIIAINFIVKEDEIEYEGIRLEEYDDSKISRYLFTDTGGNAPGYTPAAKITEVPKTFNGKIKNWFNKVLKDKSIKIDEKDRAFLERIKDILEEKSDEIIKEAEKIRGDFPKKEGLSLILKFNVDGEYKYIGDFNVFRDLMLQLDSQKYQKIYAEDKVCSICGQKKDIVFGTVDTYKFYTIDKPGYIAGGFNEKESWKNYPVCAECRLALEEGKRYLENELTFRFYGLEYQLIPNFIIGKEFVRKEVREIFESSERLLSLKREVKKRFIGDEDEILDYLADAEDSMTVNLLFLRKSNSAERILLLIEDVFPSHLREIFNAKEQVDKIFGNSFTFKNIRSFMSKSDSNKRDNDLDGYFLDITDRIFRGRPVDLGFLYNLIMKKIREEFVKDGYYKAATADGLMTIAFLEKMKLIKMEVIPMEERIFDSFFAKYGPTFEMPLKRGLVLLGALTELLLRKQYSDREAKPFMKNLKGLKMDEKDIKGLLPKVQNKLEEYDSFEKGKRLLAKEASNYLLLAGDNWNMSVDEINFYFACGINLADELTSIIYKKEGEEK
>NC_010321.1|WP_004399630.1|114957_115713_+|CRISPR-associated-endoribonuclease-Cas6
MRITLEFVGEKNLVLPIHYNYIVQGFLYDLMGDSEFAAFLHDEGFQYEKRKFKLFTFSRIEGEFKILTDSKGQKKISIKPPFKFTVASPLDEFIFDISKNALKKEYCHFNGQKFILNSLNIDNPPVFKNKARIKFISPVVMYTTLKDGDIKYTYYYSPWDEKFSPLLLNNLLKKYELVYKIKAEDPYFKLYPLSEKEDRRYSKMIKYKNVYVKGWMGIYDVESSPELLELAYYTGLGAKNSQGFGCFEIIG
>NC_010321.1|WP_003868738.1|114355_114769_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MSDLNQLYSEVIMEHYENSPHRRELKDATHKERGHNPLCGDDITLYLKMNGDIIEDASFTGHGCAISQASTSMMIDLIKGKDKKEALRLVQEFIDMIHKKDVNLDELGDAQVLHGVSDFPARVKCALLAWKTLQEIL
>NC_010321.1|WP_012268880.1|113129_114359_+|cysteine-desulfurase
MKNIDIERIKKDFPILSVKPHGKRLVYLDNAATTQKPIEVIKAMDKYYEELNANVYRSPHYLSVLSTQAYEEARERVKKFINAKKEESIVFTRNTTESINFIAYTWGMKHINEGDEILLTIAEHHSNILPWQMVAEAKGAKLKYVYLDENFRLSMKDFKEKMSEKVKLVAVQHMSNVLGIINPVEEITHIAHKYGAKVLIDGAQSVPHMPVDVQKIDCDFFAFSGHKMLGPMGIGVLYIKEDLLKEVPPFLRGGEMIDEVYEDHSTFAPSPLKFEAGTPNIEGAYVLISAIDYIEKIGLTNIYKHEGELLEYGLQKMRELDFVKLYGPKDAKERGGIISFNVEGVHPHDVATILDEEGVAVRSGHHCCQPLMRYLGVPATVRASFYLYNDFEDIDALVEGLKKVRKWFK
>NC_010321.1|WP_003869923.1|135695_136916_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|138221_139442_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012268884.1|141548_142769_-|IS110-family-transposase
MDLVYSHVCGLDVHKKSVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_009052111.1|142907_143636_+|peptidase-E
MKKVVAIGGGEISKFETFKIDEEIVKLTDKAKPKALFVPTASGEPEAYCDNFDFVYGKMLGCETDILFLIKDDPDSSQIEKKISWADLIYVGGGNTKRMMEIWRSKGVDKMLIDAYQRGTVLSGLSAGAICWFKYGFSDSQRFENQENWHYTKVEGLGLFDAILCPHLNEENRRELFEKFMIDFEGVGIGLENGCAIEIVDDTFKIINSFENAHAYVFRRSENKLFVDEIRHRDYIPFNLLI
>NC_010321.1|WP_003867574.1|143964_144462_+|CRISPR-associated-protein-Cas4
MEFEVTGALMQSYTICKRQVWLMAHQIVPDQEHPYIEIGRLIDENSYQRDRKKIHFENVVLDLVRMEKDNILIGEVKKSSKAEDSAKMQLLFYLYKLKQSGITAKGQLFFPEERKREVVELTPEFEREVIKAIEEIKDIVYKEKPPAFIKIPYCKNCGYKEFCMS
>NC_010321.1|WP_004399636.1|144458_145451_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKTIYIFSDGELKRKDNTLFFEGENGRKFIPVENTSEIMVFGEVSLNKRLLEFLTQSEIILHFFNHYGYYVGSYYPREHLNSGYMILRQAEHYNDESKRLYLAQKFVEGAYKNIRQVLKYYSNRGKDLEDVIYSIEKLGESVDSTSTINELMAIEGNIREYYYKAFDEIIQNPDFKFDFRSKRPPQNFLNTLISFGNSLMYTTTLSEIYKTHLDPRIGFLHATNFRRFSLNLDVSEIFKPIIVDRTIFTLLSKKMVTKEDFEEDAEGLLLKEKGKKVFVQEFEDKLATTIKHRNLSNNVSYRRLIRLELYKLEKHLIEEEQYKPFIAQW
>NC_010321.1|WP_003871087.1|145467_145731_+|CRISPR-associated-endonuclease-Cas2
MFLILVYDVNEKRVNKVLKTCRKYLHWVQNSVLEGEISEANLKKLKIELSRIIDKDEDSVIFYILRTTKYSEREILGLRKGGEDIII
>NC_010321.1|WP_012268885.1|145851_147777_+|FAD-dependent-oxidoreductase
MELTKPIKIGNLSLKNRVVMAPVKTGYATPEGQVTEELIQYYVNRAKGGVGLIVLESAYVDLSGKEIPRQLGIYDDSMVEGLRRLITPLQEAGSKVAVYINHAGRIANPMVTKLPLIAPSSIACPTIGVEPQGIPHEDIKKWQNTYVKAAVRAYEAGADALEIQFGHGYLIHQFLSPHTNKREDEYGGSFENRIRFGMEILDEIKKEIGADFPIIVRISADEFVPGGWALEDAIRLAKILEDKGVAAIDVSLGSSCESGAITLQTLGTQKGLAWEFASKIKKQVNIPVIAVGRINTPELAEEILVSGKADLVALGRPLVADPLFVEKATSGRSKEIRRCAACHQGCLDELRAGRRFGCNFNPSVGKEEEIEIQKAPQPGKKVFIIGAGLAGLEAAYTAAARGHKVYIYEEKGEIGGQVLPGSVPPHKEELKGIVEYYKEVLPKVGVTLNLNHKVTAEEIAKWEADEVVFATGGQPIVPPIPGLKEYGFLTAVEVLRGEKQAGDKVAIIGGGLIGMETADYLSEQGKKVMVIELLEEVARDMGVFEKILIMKRLKERGVEIYVKTRLKEVGKALLVETPEGEKELPLPDTIVLAVGLKPDPSLYEEVSKILPQEKLHVIGDAKEVRKIVHAISEGRNLGLSL
>NC_010321.1|WP_003871085.1|148037_148817_+|MBL-fold-metallo-hydrolase
MKFCSLRSGSSGNAIYINHKDVHILVDAGLSGRTIEKALLNIGINPKSLSAILITHEHKDHIIGAGVLSRRYNIPIYANKATWEVMEKDIKEISEKNKLYFTTGEEFEIGDVKIMPFKKSHDAVEPVGFSFKCGDKKISIATDLGYMTRGVANHLIGSDIVLLEANHDIEMLINGSYPWPLKKRILSNLGHLSNDAAADTLMKLFKMKAIGIAFLGHLSQNNNRPELAFATVTNVLKKSGVKFEVRMALRNIESDLVEI
>NC_010321.1|WP_012268886.1|149271_150684_+|group-II-intron-reverse-transcriptase/maturase
MDSKDMQRLQTTQQRGYPLNREMEFQKTTEVHSISSASEDGRNEVQRYTSKMLEMIVERGNMEAAYKRVVANKGSHGVDGMEVDELLPYLKENWATIKQQLLEGKYKPQPVRRVEISKPDGGVRLLGIPTALDRLIQQAIAQILNRVYNHTFSDSSYGFRPGRSAKDAIKAAEAYINEGYTWVVDMDLEKFFDRVNHDIIMSKLEKRIGDKRVLKLIRRYLESGVMINGIKVSTEEGTPQGGPLSPLLANIMLDELDKELEKRGHKFCRYADDCNIYVKSRSAGNRVMKSIKKFIESKLKLKINEAKSAVDRPWRRKFLGFSFYTKENEVRIRIHEKSIKRFKEKVREITNRNKGISMENRIKRLNQITTGWVNYFGLADAKSIMKTLDEWIRRRLRACIWKQWKKIKTKHDNLVKLGVEEQKAWEYANTRKGYWRISNSPILNKTLTNKYFESIGYKSLSQRYLIVHNS

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Crispr_ID: NC_010321_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010321_4

134718-135610

TypeI-B

Consensus_repeat	Method
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder

13 spacers

cas3,cas5,cas7,cas8b1,cas6,cas4,cas1,cas2,RT

The CRISPR arrays of NC_010321_4

>merge|NC_010321|4|134718-135610|CRT,PILER-CR,CRISPRCasFinder
GCGGCATGGGAGTCTATAAGGAATTGAAACGTTTTTTGTACATTTCACTATCAAGGATTTTTCTATGTTTTTAGCCTACCTATAAGGAATTGAAACTGCCGTCTGTGCCTTGCGAATATTCTACGTCGCCGAGTTTTTAGCCTACCTATAAGGAATTGAAACTGTTGAAGACATATATCTGAAAGTTGTATCAAAAAAGTTTTTAGCCTACCTATAAGGAATTGAAACAGCTCTTCTACTGCTCTTCTTCCTCTGCGATAAACAGTTTTTAGCCTACCTATAAGGAATTGAAACACAAAACAACTCGCTGGGATAGAACAATTAGAAGAAAGTTTTTAGCCTACCTATAAGGAATTGAAACTAGGCTTCTAGCGTTACACCAATAGGCTCTGTCGGGTGTTTTTAGCCTACCTATAAGGAATTGAAACAGGAGTTAATACTGCGACTGCACTTAAAACAGCCATAAGTTTTTAGCCTACCTATAAGGAATTGAAACCTTAGCAGCGTTGATACATGCCTAATACCATCAAGGGTTTTTAGCCTACCTATAAGGAATTGAAACAGTCCATATCGCCATTTACATAGTAGACTACTTCTTTGTTTTTAGCCTACCTATAAGGAATTGAAACGAGCAGAAATGGAATTGCATGGCTATGCAGCAGAAGTTTTTAGCCTACCTATAAGGAATTGAAACTTAAAAAGCCTGCCCTTTTGCAGTTAATAGTCTCTTAGTTTTTAGCCTACCTATAAGGAATTGAAACTAGGCAATGTTTATGCATCCGAGCTAGGGCTATCCTGTTTTTAGCCTACCTATAAGGAATTGAAACCCGCCACATACATCCAAACAGGAAGTACCAGCATGGGTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|4|4|134718-135610|CRT
GCGGCATGGGAGTCTATAAGGAATTGAAAC	GTTTTTTGTACATTTCACTATCAAGGATTTTTCTAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCCGTCTGTGCCTTGCGAATATTCTACGTCGCCGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTTGAAGACATATATCTGAAAGTTGTATCAAAAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTCTTCTACTGCTCTTCTTCCTCTGCGATAAACA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAAAACAACTCGCTGGGATAGAACAATTAGAAGAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGGCTTCTAGCGTTACACCAATAGGCTCTGTCGGGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGGAGTTAATACTGCGACTGCACTTAAAACAGCCATAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CTTAGCAGCGTTGATACATGCCTAATACCATCAAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTCCATATCGCCATTTACATAGTAGACTACTTCTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GAGCAGAAATGGAATTGCATGGCTATGCAGCAGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTAAAAAGCCTGCCCTTTTGCAGTTAATAGTCTCTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGGCAATGTTTATGCATCCGAGCTAGGGCTATCCT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCGCCACATACATCCAAACAGGAAGTACCAGCATGG
GTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|4|4|134784-135544|PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCCGTCTGTGCCTTGCGAATATTCTACGTCGCCGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTTGAAGACATATATCTGAAAGTTGTATCAAAAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTCTTCTACTGCTCTTCTTCCTCTGCGATAAACA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAAAACAACTCGCTGGGATAGAACAATTAGAAGAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGGCTTCTAGCGTTACACCAATAGGCTCTGTCGGGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGGAGTTAATACTGCGACTGCACTTAAAACAGCCATAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CTTAGCAGCGTTGATACATGCCTAATACCATCAAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTCCATATCGCCATTTACATAGTAGACTACTTCTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GAGCAGAAATGGAATTGCATGGCTATGCAGCAGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTAAAAAGCCTGCCCTTTTGCAGTTAATAGTCTCTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGGCAATGTTTATGCATCCGAGCTAGGGCTATCCT
GTTTTTAGCCTACCTATAAGGAATTGAAAC

>NC_010321|4|4|134784-135610|CRISPRCasFinder
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGCCGTCTGTGCCTTGCGAATATTCTACGTCGCCGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTTGAAGACATATATCTGAAAGTTGTATCAAAAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTCTTCTACTGCTCTTCTTCCTCTGCGATAAACA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACAAAACAACTCGCTGGGATAGAACAATTAGAAGAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGGCTTCTAGCGTTACACCAATAGGCTCTGTCGGGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGGAGTTAATACTGCGACTGCACTTAAAACAGCCATAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CTTAGCAGCGTTGATACATGCCTAATACCATCAAGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTCCATATCGCCATTTACATAGTAGACTACTTCTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GAGCAGAAATGGAATTGCATGGCTATGCAGCAGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTAAAAAGCCTGCCCTTTTGCAGTTAATAGTCTCTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAGGCAATGTTTATGCATCCGAGCTAGGGCTATCCT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCGCCACATACATCCAAACAGGAAGTACCAGCATGG
GTTTTTAGCCTACCTATCCTGAAAATAGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	unknown	unknown	gnl\|CDD\|153240
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268880.1\|113129_114359_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NC_010321.1\|WP_003868738.1\|114355_114769_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NC_010321.1\|WP_012268886.1\|149271_150684_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003871085.1\|148037_148817_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293819
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_010321.1\|WP_012268885.1\|145851_147777_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274912

Protein	Function_ID	Function_description	E-value
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	2.8809e-41
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	2.64608e-180
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	gnl\|CDD\|153240	cd03146, GAT1_Peptidase_E, Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. This group contains proteins similar to the aspartyl dipeptidases Salmonella typhimurium peptidase E and Xenopus laevis peptidase E. In bacteria peptidase E is believed to play a role in degrading peptides generated by intracellular protein breakdown or imported into the cell as nutrient sources. Peptidase E uniquely hydrolyses only Asp-X dipeptides (where X is any amino acid), and one tripeptide Asp-Gly-Gly. Peptidase E is believed to be a serine peptidase having a Ser-His-Glu catalytic triad which differs from the Cys-His-Glu catalytic triad typical of GATase1 domains by having a Ser in place of the reactive Cys at the nucleophile elbow. Xenopus PepE is developmentally regulated in response to thyroid hormone and, it is thought to play a role in apoptosis during tail reabsorption.	1.63934e-66
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268880.1\|113129_114359_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_010321.1\|WP_003868738.1\|114355_114769_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.66901e-73
NC_010321.1\|WP_012268886.1\|149271_150684_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	0
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.54792e-93
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	8.76406e-41
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	6.26269e-66
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003871085.1\|148037_148817_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293819	cd07733, YycJ-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis YycJ and related proteins; MBL-fold metallo hydrolase domain. Includes the uncharacterized Bacillus subtilis YycJ protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.17177e-57
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	4.21073e-159
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.16445e-42
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	8.0037e-34
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.27175e-45
NC_010321.1\|WP_012268885.1\|145851_147777_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|274912	TIGR03997, NADH:flavin_oxidoreductase, mycofactocin system FadH/OYE family oxidoreductase 2. The yeast protein called old yellow enzyme and FadH from Escherichia coli (2,4-dienoyl CoA reductase) are enzymes with 4Fe-4S, FMN, and FAD prosthetic groups, and interact with NADPH as well as substrate. Members of this related protein family occur in the vicinity of the putative mycofactocin biosynthesis operon in a number of Actinobacteria such as Frankia sp. and Rhodococcus sp., in Pelotomaculum thermopropionicum SI (Firmicutes), and in Geobacter uraniireducens Rf4 (Deltaproteobacteria). The function of this oxidoreductase is unknown.	2.09042e-149

>NC_010321.1|WP_003869923.1|129769_130990_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|128110_129331_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|124977_126198_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012268883.1|119117_121472_+|CRISPR-associated-helicase/endonuclease-Cas3
MSSFSELYSHPDKFLEDHLINTSKIIRSYFNEKKVAIIDKETFLKTATIISLCHDFGKATNYFQKYLFTENEKERNKLKTMEEMHHSLLSAVVAFYLVKNEINAQDRKGILFPFIAFLIVKNHHGDLKNVFNEVILDDKELEVLKKQLNSIDDEKLQVLNGKLRNAGLNENLTKSAINDYIDSINSELRKIKRELRRLKEEQDVSIYLLLNFLFSLLVDADKTEVVVGIDNIKRPEIKFEEQLVKEYKASFPDKESKINLLREEAYKEVLEKDIDIKQKIMSINLPTGLGKTLTTIAFAMKLWAKLYKETGVKYRIIYSLPFLSIIEQNSNVLEDLLRYNGIQPDTEIILKHHHLSDIRYTKNNTEFEDEQAKILIEGWNSEIIITTFVQFFHTLVSEKNKTLRKFHRLANSIIILDEVQSIPFKYWLLTKELLKAVANELNSYIIFVTATQPLIFREEEIYPLVAKTKYFTQMDRVEIIPKLSRDITLEELSEMFDLNDGKSYLFILNTIKSAQQFYNILRAKIPNDEIIYMSTHVVPMERMERIEKIKEGKIRFAVTTQLVEAGVDIDFDVVVRDIAPLDSINQSAGRCNRNWRGKGEVYVVSLIDEKGQKYSKYVYDKILLGITREILSKYDTIKEQELLKIIEKYYQEVSERMSSNEGRELLDAIYTLRYDSEDGNMCISKFELIEDDYYKVDAFIELNDEAKELWHKYVELKDIKNLFERRNIFNRFKADFYKYVISIPATVENMPPDIWGFKYVNYDSLNDYYDKETGFITKGVTSIW
>NC_010321.1|WP_003871404.1|118420_119134_+|type-I-B-CRISPR-associated-protein-Cas5
MKTLVFDVFGDYGHFRKYYTTSSPLTFSFPPPPTVKGMLGAIAGIDKKEYLKVFSEENCKVAIRILNPIKKIRLGLNLINTKGNYWIPYKAKNHEARTQVKTEFVKDAAYRIYFMHKDNDLFEDIVEKIKNRRNVYTLSLGLSEMIADYKFIGVYEAEEIENAEVDILSVLPFQSIVEDKIYFENGKKYFKEKIPAGMNEDRVVLSYEDVLYEVNGQSIKCHVKKCWEVKGEHVIFF
>NC_010321.1|WP_012268882.1|117496_118408_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MENVIKNRAEILFLYDVSFANPNGDPVDENKPRIDEETGINIVTDVRLKRTIRDYLAYYKGKEVFIIETRKDNGELRTKKDRIEDFGTNEDIIAKCIDVRLFGATTAVKDKMMILTGPVQFKYGKSLHRVNLMYVKGTTVMPSGEGREQGTFTEKYILPYSLIAFYGIVNENAAINQNIPLTDEDVDLMLEGMWNGTKNLMSGSKIGHMPRLLIEVVYQENNYQIGELEKRIKFVHEMEDEEIRDIQDGKLDITELVAVLKQNQEKIKLIKYIYDDRVTFTCNGEECTLEKALKGLNIQKLQY
>NC_010321.1|WP_012268881.1|115732_117496_+|TIGR02556-family-CRISPR-associated-protein
MITAIKELGEMVLKSQNKTLLDVLIENPNQDGRYSKIIAINFIVKEDEIEYEGIRLEEYDDSKISRYLFTDTGGNAPGYTPAAKITEVPKTFNGKIKNWFNKVLKDKSIKIDEKDRAFLERIKDILEEKSDEIIKEAEKIRGDFPKKEGLSLILKFNVDGEYKYIGDFNVFRDLMLQLDSQKYQKIYAEDKVCSICGQKKDIVFGTVDTYKFYTIDKPGYIAGGFNEKESWKNYPVCAECRLALEEGKRYLENELTFRFYGLEYQLIPNFIIGKEFVRKEVREIFESSERLLSLKREVKKRFIGDEDEILDYLADAEDSMTVNLLFLRKSNSAERILLLIEDVFPSHLREIFNAKEQVDKIFGNSFTFKNIRSFMSKSDSNKRDNDLDGYFLDITDRIFRGRPVDLGFLYNLIMKKIREEFVKDGYYKAATADGLMTIAFLEKMKLIKMEVIPMEERIFDSFFAKYGPTFEMPLKRGLVLLGALTELLLRKQYSDREAKPFMKNLKGLKMDEKDIKGLLPKVQNKLEEYDSFEKGKRLLAKEASNYLLLAGDNWNMSVDEINFYFACGINLADELTSIIYKKEGEEK
>NC_010321.1|WP_004399630.1|114957_115713_+|CRISPR-associated-endoribonuclease-Cas6
MRITLEFVGEKNLVLPIHYNYIVQGFLYDLMGDSEFAAFLHDEGFQYEKRKFKLFTFSRIEGEFKILTDSKGQKKISIKPPFKFTVASPLDEFIFDISKNALKKEYCHFNGQKFILNSLNIDNPPVFKNKARIKFISPVVMYTTLKDGDIKYTYYYSPWDEKFSPLLLNNLLKKYELVYKIKAEDPYFKLYPLSEKEDRRYSKMIKYKNVYVKGWMGIYDVESSPELLELAYYTGLGAKNSQGFGCFEIIG
>NC_010321.1|WP_003868738.1|114355_114769_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MSDLNQLYSEVIMEHYENSPHRRELKDATHKERGHNPLCGDDITLYLKMNGDIIEDASFTGHGCAISQASTSMMIDLIKGKDKKEALRLVQEFIDMIHKKDVNLDELGDAQVLHGVSDFPARVKCALLAWKTLQEIL
>NC_010321.1|WP_012268880.1|113129_114359_+|cysteine-desulfurase
MKNIDIERIKKDFPILSVKPHGKRLVYLDNAATTQKPIEVIKAMDKYYEELNANVYRSPHYLSVLSTQAYEEARERVKKFINAKKEESIVFTRNTTESINFIAYTWGMKHINEGDEILLTIAEHHSNILPWQMVAEAKGAKLKYVYLDENFRLSMKDFKEKMSEKVKLVAVQHMSNVLGIINPVEEITHIAHKYGAKVLIDGAQSVPHMPVDVQKIDCDFFAFSGHKMLGPMGIGVLYIKEDLLKEVPPFLRGGEMIDEVYEDHSTFAPSPLKFEAGTPNIEGAYVLISAIDYIEKIGLTNIYKHEGELLEYGLQKMRELDFVKLYGPKDAKERGGIISFNVEGVHPHDVATILDEEGVAVRSGHHCCQPLMRYLGVPATVRASFYLYNDFEDIDALVEGLKKVRKWFK
>NC_010321.1|WP_003869923.1|135695_136916_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|138221_139442_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012268884.1|141548_142769_-|IS110-family-transposase
MDLVYSHVCGLDVHKKSVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_009052111.1|142907_143636_+|peptidase-E
MKKVVAIGGGEISKFETFKIDEEIVKLTDKAKPKALFVPTASGEPEAYCDNFDFVYGKMLGCETDILFLIKDDPDSSQIEKKISWADLIYVGGGNTKRMMEIWRSKGVDKMLIDAYQRGTVLSGLSAGAICWFKYGFSDSQRFENQENWHYTKVEGLGLFDAILCPHLNEENRRELFEKFMIDFEGVGIGLENGCAIEIVDDTFKIINSFENAHAYVFRRSENKLFVDEIRHRDYIPFNLLI
>NC_010321.1|WP_003867574.1|143964_144462_+|CRISPR-associated-protein-Cas4
MEFEVTGALMQSYTICKRQVWLMAHQIVPDQEHPYIEIGRLIDENSYQRDRKKIHFENVVLDLVRMEKDNILIGEVKKSSKAEDSAKMQLLFYLYKLKQSGITAKGQLFFPEERKREVVELTPEFEREVIKAIEEIKDIVYKEKPPAFIKIPYCKNCGYKEFCMS
>NC_010321.1|WP_004399636.1|144458_145451_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKTIYIFSDGELKRKDNTLFFEGENGRKFIPVENTSEIMVFGEVSLNKRLLEFLTQSEIILHFFNHYGYYVGSYYPREHLNSGYMILRQAEHYNDESKRLYLAQKFVEGAYKNIRQVLKYYSNRGKDLEDVIYSIEKLGESVDSTSTINELMAIEGNIREYYYKAFDEIIQNPDFKFDFRSKRPPQNFLNTLISFGNSLMYTTTLSEIYKTHLDPRIGFLHATNFRRFSLNLDVSEIFKPIIVDRTIFTLLSKKMVTKEDFEEDAEGLLLKEKGKKVFVQEFEDKLATTIKHRNLSNNVSYRRLIRLELYKLEKHLIEEEQYKPFIAQW
>NC_010321.1|WP_003871087.1|145467_145731_+|CRISPR-associated-endonuclease-Cas2
MFLILVYDVNEKRVNKVLKTCRKYLHWVQNSVLEGEISEANLKKLKIELSRIIDKDEDSVIFYILRTTKYSEREILGLRKGGEDIII
>NC_010321.1|WP_012268885.1|145851_147777_+|FAD-dependent-oxidoreductase
MELTKPIKIGNLSLKNRVVMAPVKTGYATPEGQVTEELIQYYVNRAKGGVGLIVLESAYVDLSGKEIPRQLGIYDDSMVEGLRRLITPLQEAGSKVAVYINHAGRIANPMVTKLPLIAPSSIACPTIGVEPQGIPHEDIKKWQNTYVKAAVRAYEAGADALEIQFGHGYLIHQFLSPHTNKREDEYGGSFENRIRFGMEILDEIKKEIGADFPIIVRISADEFVPGGWALEDAIRLAKILEDKGVAAIDVSLGSSCESGAITLQTLGTQKGLAWEFASKIKKQVNIPVIAVGRINTPELAEEILVSGKADLVALGRPLVADPLFVEKATSGRSKEIRRCAACHQGCLDELRAGRRFGCNFNPSVGKEEEIEIQKAPQPGKKVFIIGAGLAGLEAAYTAAARGHKVYIYEEKGEIGGQVLPGSVPPHKEELKGIVEYYKEVLPKVGVTLNLNHKVTAEEIAKWEADEVVFATGGQPIVPPIPGLKEYGFLTAVEVLRGEKQAGDKVAIIGGGLIGMETADYLSEQGKKVMVIELLEEVARDMGVFEKILIMKRLKERGVEIYVKTRLKEVGKALLVETPEGEKELPLPDTIVLAVGLKPDPSLYEEVSKILPQEKLHVIGDAKEVRKIVHAISEGRNLGLSL
>NC_010321.1|WP_003871085.1|148037_148817_+|MBL-fold-metallo-hydrolase
MKFCSLRSGSSGNAIYINHKDVHILVDAGLSGRTIEKALLNIGINPKSLSAILITHEHKDHIIGAGVLSRRYNIPIYANKATWEVMEKDIKEISEKNKLYFTTGEEFEIGDVKIMPFKKSHDAVEPVGFSFKCGDKKISIATDLGYMTRGVANHLIGSDIVLLEANHDIEMLINGSYPWPLKKRILSNLGHLSNDAAADTLMKLFKMKAIGIAFLGHLSQNNNRPELAFATVTNVLKKSGVKFEVRMALRNIESDLVEI
>NC_010321.1|WP_012268886.1|149271_150684_+|group-II-intron-reverse-transcriptase/maturase
MDSKDMQRLQTTQQRGYPLNREMEFQKTTEVHSISSASEDGRNEVQRYTSKMLEMIVERGNMEAAYKRVVANKGSHGVDGMEVDELLPYLKENWATIKQQLLEGKYKPQPVRRVEISKPDGGVRLLGIPTALDRLIQQAIAQILNRVYNHTFSDSSYGFRPGRSAKDAIKAAEAYINEGYTWVVDMDLEKFFDRVNHDIIMSKLEKRIGDKRVLKLIRRYLESGVMINGIKVSTEEGTPQGGPLSPLLANIMLDELDKELEKRGHKFCRYADDCNIYVKSRSAGNRVMKSIKKFIESKLKLKINEAKSAVDRPWRRKFLGFSFYTKENEVRIRIHEKSIKRFKEKVREITNRNKGISMENRIKRLNQITTGWVNYFGLADAKSIMKTLDEWIRRRLRACIWKQWKKIKTKHDNLVKLGVEEQKAWEYANTRKGYWRISNSPILNKTLTNKYFESIGYKSLSQRYLIVHNS

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Crispr_ID: NC_010321_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010321_5

137174-138136

Unclear

Consensus_repeat	Method
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder

14 spacers

cas3,cas5,cas7,cas8b1,cas6,cas4,cas1,cas2,RT

The CRISPR arrays of NC_010321_5

>merge|NC_010321|5|137174-138136|CRT,PILER-CR,CRISPRCasFinder
GCGGCATGGGAGTCTATAAGGAATTGAAACAGAAGAATATTGACAGTTTAACTGCTCAAAAGATAGCGTTTTTAGCCTACCTATAAGGAATTGAAACACTGTCCCTCAATTTCCTTGTTTTCCTCCTTAAGCTTGTTTTTAGCCTACCTATAAGGAATTGAAACTAAACCGCCAGAATGCTGAAGCCATATTCCTCGCACGTTTTTAGCCTACCTATAAGGAATTGAAACATAACTCCGTTTGGTTTTTCGGGGTTTTGCTGAATAGTTTTTAGCCTACCTATAAGGAATTGAAACATTATCTCTTGAAGCGCCTTTGCAGTGTCGAATTTTTGTTTTTAGCCTACCTATAAGGAATTGAAACTTTGGAATTCCTTTAGGCGCTCGAACTCACCCATCTGGTTTTTAGCCTACCTATAAGGAATTGAAACAAATACTCGCCGGCGCGAACCTTAATCTTCACCGGCCAGTTTTTAGCCTACCTATAAGGAATTGAAACCCCATAACCTTGGGAACACAAATTATATGGTGAACATGTTTTTAGCCTACCTATAAGGAATTGAAACAGAAACTCGCAGAACCCGGCCAACCTGCTGGCTATAGGTTTTTAGCCTACCTATAAGGAATTGAAACATAAAAAAGTTCCCCGTTGTTACCTCATGTTGCTGTGTTTTTAGCCTACCTATAAGGAATTGAAACCAAGATAAATGGGATAGCCTTGTTGAGGCAGCAAAAAGTTTTTAGCCTACCTATAAGGAATTGAAACCCAACGCTCCCGGTGGTCTTGCGCTGTTCTGGAGTAGTTTTTAGCCTACCTATAAGGAATTGAAACATGTCTAACCTATCAAGTACGTCTTTTATTGCTTGGTTTTTAGCCTACCTATAAGGAATTGAAACTGGATAGCAAAGGCAAGTGCAGAACTGGATAAAAAGAGTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|5|5|137174-138136|CRT
GCGGCATGGGAGTCTATAAGGAATTGAAAC	AGAAGAATATTGACAGTTTAACTGCTCAAAAGATAGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACTGTCCCTCAATTTCCTTGTTTTCCTCCTTAAGCTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAACCGCCAGAATGCTGAAGCCATATTCCTCGCAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATAACTCCGTTTGGTTTTTCGGGGTTTTGCTGAATA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTATCTCTTGAAGCGCCTTTGCAGTGTCGAATTTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTGGAATTCCTTTAGGCGCTCGAACTCACCCATCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAATACTCGCCGGCGCGAACCTTAATCTTCACCGGCCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCCATAACCTTGGGAACACAAATTATATGGTGAACAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGAAACTCGCAGAACCCGGCCAACCTGCTGGCTATAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATAAAAAAGTTCCCCGTTGTTACCTCATGTTGCTGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAAGATAAATGGGATAGCCTTGTTGAGGCAGCAAAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAACGCTCCCGGTGGTCTTGCGCTGTTCTGGAGTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGTCTAACCTATCAAGTACGTCTTTTATTGCTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGATAGCAAAGGCAAGTGCAGAACTGGATAAAAAGA
GTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|5|5|137241-138069|PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACTGTCCCTCAATTTCCTTGTTTTCCTCCTTAAGCTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAACCGCCAGAATGCTGAAGCCATATTCCTCGCAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATAACTCCGTTTGGTTTTTCGGGGTTTTGCTGAATA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTATCTCTTGAAGCGCCTTTGCAGTGTCGAATTTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTGGAATTCCTTTAGGCGCTCGAACTCACCCATCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAATACTCGCCGGCGCGAACCTTAATCTTCACCGGCCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCCATAACCTTGGGAACACAAATTATATGGTGAACAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGAAACTCGCAGAACCCGGCCAACCTGCTGGCTATAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATAAAAAAGTTCCCCGTTGTTACCTCATGTTGCTGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAAGATAAATGGGATAGCCTTGTTGAGGCAGCAAAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAACGCTCCCGGTGGTCTTGCGCTGTTCTGGAGTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGTCTAACCTATCAAGTACGTCTTTTATTGCTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC

>NC_010321|5|5|137241-138136|CRISPRCasFinder
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACTGTCCCTCAATTTCCTTGTTTTCCTCCTTAAGCTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAAACCGCCAGAATGCTGAAGCCATATTCCTCGCAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATAACTCCGTTTGGTTTTTCGGGGTTTTGCTGAATA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTATCTCTTGAAGCGCCTTTGCAGTGTCGAATTTTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTGGAATTCCTTTAGGCGCTCGAACTCACCCATCTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAATACTCGCCGGCGCGAACCTTAATCTTCACCGGCCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCCATAACCTTGGGAACACAAATTATATGGTGAACAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGAAACTCGCAGAACCCGGCCAACCTGCTGGCTATAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATAAAAAAGTTCCCCGTTGTTACCTCATGTTGCTGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CAAGATAAATGGGATAGCCTTGTTGAGGCAGCAAAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAACGCTCCCGGTGGTCTTGCGCTGTTCTGGAGTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGTCTAACCTATCAAGTACGTCTTTTATTGCTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGATAGCAAAGGCAAGTGCAGAACTGGATAAAAAGA
GTTTTTAGCCTACCTATCCTGAAAATAGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	unknown	unknown	gnl\|CDD\|153240
NC_010321.1\|WP_003867580.1\|150923_151364_+\|ACT-domain-containing-protein	unknown	unknown	gnl\|CDD\|179848
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003868738.1\|114355_114769_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	unknown	unknown	gnl\|CDD\|273918
NC_010321.1\|WP_012268886.1\|149271_150684_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003871085.1\|148037_148817_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293819
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_010321.1\|WP_012268885.1\|145851_147777_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274912

Protein	Function_ID	Function_description	E-value
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	2.8809e-41
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	2.64608e-180
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	gnl\|CDD\|153240	cd03146, GAT1_Peptidase_E, Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. This group contains proteins similar to the aspartyl dipeptidases Salmonella typhimurium peptidase E and Xenopus laevis peptidase E. In bacteria peptidase E is believed to play a role in degrading peptides generated by intracellular protein breakdown or imported into the cell as nutrient sources. Peptidase E uniquely hydrolyses only Asp-X dipeptides (where X is any amino acid), and one tripeptide Asp-Gly-Gly. Peptidase E is believed to be a serine peptidase having a Ser-His-Glu catalytic triad which differs from the Cys-His-Glu catalytic triad typical of GATase1 domains by having a Ser in place of the reactive Cys at the nucleophile elbow. Xenopus PepE is developmentally regulated in response to thyroid hormone and, it is thought to play a role in apoptosis during tail reabsorption.	1.63934e-66
NC_010321.1\|WP_003867580.1\|150923_151364_+\|ACT-domain-containing-protein	gnl\|CDD\|179848	PRK04435, PRK04435, ACT domain-containing protein.	4.00304e-77
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003868738.1\|114355_114769_+\|SUF-system-NifU-family-Fe-S-cluster-assembly-protein	gnl\|CDD\|273918	TIGR01994, Iron-sulfur_cluster_assembly_scaffold_protein_IscU, SUF system FeS assembly protein, NifU family. Three iron-sulfur cluster assembly systems are known so far. ISC is broadly distributed while NIF tends to be associated with nitrogenase in nitrogen-fixing bacteria. The most recently described is SUF, believed to be important to maintain the function during aerobic stress of enzymes with labile Fe-S clusters. It is fairly widely distributed. This family represents one of two different proteins proposed to act as a scaffold on which the Fe-S cluster is built and from which it is transferred. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	1.66901e-73
NC_010321.1\|WP_012268886.1\|149271_150684_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	0
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.54792e-93
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	8.76406e-41
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	6.26269e-66
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003871085.1\|148037_148817_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293819	cd07733, YycJ-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis YycJ and related proteins; MBL-fold metallo hydrolase domain. Includes the uncharacterized Bacillus subtilis YycJ protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.17177e-57
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	4.21073e-159
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.16445e-42
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	8.0037e-34
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.27175e-45
NC_010321.1\|WP_012268885.1\|145851_147777_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|274912	TIGR03997, NADH:flavin_oxidoreductase, mycofactocin system FadH/OYE family oxidoreductase 2. The yeast protein called old yellow enzyme and FadH from Escherichia coli (2,4-dienoyl CoA reductase) are enzymes with 4Fe-4S, FMN, and FAD prosthetic groups, and interact with NADPH as well as substrate. Members of this related protein family occur in the vicinity of the putative mycofactocin biosynthesis operon in a number of Actinobacteria such as Frankia sp. and Rhodococcus sp., in Pelotomaculum thermopropionicum SI (Firmicutes), and in Geobacter uraniireducens Rf4 (Deltaproteobacteria). The function of this oxidoreductase is unknown.	2.09042e-149

>NC_010321.1|WP_003869923.1|135695_136916_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|129769_130990_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|128110_129331_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|124977_126198_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012268883.1|119117_121472_+|CRISPR-associated-helicase/endonuclease-Cas3
MSSFSELYSHPDKFLEDHLINTSKIIRSYFNEKKVAIIDKETFLKTATIISLCHDFGKATNYFQKYLFTENEKERNKLKTMEEMHHSLLSAVVAFYLVKNEINAQDRKGILFPFIAFLIVKNHHGDLKNVFNEVILDDKELEVLKKQLNSIDDEKLQVLNGKLRNAGLNENLTKSAINDYIDSINSELRKIKRELRRLKEEQDVSIYLLLNFLFSLLVDADKTEVVVGIDNIKRPEIKFEEQLVKEYKASFPDKESKINLLREEAYKEVLEKDIDIKQKIMSINLPTGLGKTLTTIAFAMKLWAKLYKETGVKYRIIYSLPFLSIIEQNSNVLEDLLRYNGIQPDTEIILKHHHLSDIRYTKNNTEFEDEQAKILIEGWNSEIIITTFVQFFHTLVSEKNKTLRKFHRLANSIIILDEVQSIPFKYWLLTKELLKAVANELNSYIIFVTATQPLIFREEEIYPLVAKTKYFTQMDRVEIIPKLSRDITLEELSEMFDLNDGKSYLFILNTIKSAQQFYNILRAKIPNDEIIYMSTHVVPMERMERIEKIKEGKIRFAVTTQLVEAGVDIDFDVVVRDIAPLDSINQSAGRCNRNWRGKGEVYVVSLIDEKGQKYSKYVYDKILLGITREILSKYDTIKEQELLKIIEKYYQEVSERMSSNEGRELLDAIYTLRYDSEDGNMCISKFELIEDDYYKVDAFIELNDEAKELWHKYVELKDIKNLFERRNIFNRFKADFYKYVISIPATVENMPPDIWGFKYVNYDSLNDYYDKETGFITKGVTSIW
>NC_010321.1|WP_003871404.1|118420_119134_+|type-I-B-CRISPR-associated-protein-Cas5
MKTLVFDVFGDYGHFRKYYTTSSPLTFSFPPPPTVKGMLGAIAGIDKKEYLKVFSEENCKVAIRILNPIKKIRLGLNLINTKGNYWIPYKAKNHEARTQVKTEFVKDAAYRIYFMHKDNDLFEDIVEKIKNRRNVYTLSLGLSEMIADYKFIGVYEAEEIENAEVDILSVLPFQSIVEDKIYFENGKKYFKEKIPAGMNEDRVVLSYEDVLYEVNGQSIKCHVKKCWEVKGEHVIFF
>NC_010321.1|WP_012268882.1|117496_118408_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MENVIKNRAEILFLYDVSFANPNGDPVDENKPRIDEETGINIVTDVRLKRTIRDYLAYYKGKEVFIIETRKDNGELRTKKDRIEDFGTNEDIIAKCIDVRLFGATTAVKDKMMILTGPVQFKYGKSLHRVNLMYVKGTTVMPSGEGREQGTFTEKYILPYSLIAFYGIVNENAAINQNIPLTDEDVDLMLEGMWNGTKNLMSGSKIGHMPRLLIEVVYQENNYQIGELEKRIKFVHEMEDEEIRDIQDGKLDITELVAVLKQNQEKIKLIKYIYDDRVTFTCNGEECTLEKALKGLNIQKLQY
>NC_010321.1|WP_012268881.1|115732_117496_+|TIGR02556-family-CRISPR-associated-protein
MITAIKELGEMVLKSQNKTLLDVLIENPNQDGRYSKIIAINFIVKEDEIEYEGIRLEEYDDSKISRYLFTDTGGNAPGYTPAAKITEVPKTFNGKIKNWFNKVLKDKSIKIDEKDRAFLERIKDILEEKSDEIIKEAEKIRGDFPKKEGLSLILKFNVDGEYKYIGDFNVFRDLMLQLDSQKYQKIYAEDKVCSICGQKKDIVFGTVDTYKFYTIDKPGYIAGGFNEKESWKNYPVCAECRLALEEGKRYLENELTFRFYGLEYQLIPNFIIGKEFVRKEVREIFESSERLLSLKREVKKRFIGDEDEILDYLADAEDSMTVNLLFLRKSNSAERILLLIEDVFPSHLREIFNAKEQVDKIFGNSFTFKNIRSFMSKSDSNKRDNDLDGYFLDITDRIFRGRPVDLGFLYNLIMKKIREEFVKDGYYKAATADGLMTIAFLEKMKLIKMEVIPMEERIFDSFFAKYGPTFEMPLKRGLVLLGALTELLLRKQYSDREAKPFMKNLKGLKMDEKDIKGLLPKVQNKLEEYDSFEKGKRLLAKEASNYLLLAGDNWNMSVDEINFYFACGINLADELTSIIYKKEGEEK
>NC_010321.1|WP_004399630.1|114957_115713_+|CRISPR-associated-endoribonuclease-Cas6
MRITLEFVGEKNLVLPIHYNYIVQGFLYDLMGDSEFAAFLHDEGFQYEKRKFKLFTFSRIEGEFKILTDSKGQKKISIKPPFKFTVASPLDEFIFDISKNALKKEYCHFNGQKFILNSLNIDNPPVFKNKARIKFISPVVMYTTLKDGDIKYTYYYSPWDEKFSPLLLNNLLKKYELVYKIKAEDPYFKLYPLSEKEDRRYSKMIKYKNVYVKGWMGIYDVESSPELLELAYYTGLGAKNSQGFGCFEIIG
>NC_010321.1|WP_003868738.1|114355_114769_+|SUF-system-NifU-family-Fe-S-cluster-assembly-protein
MSDLNQLYSEVIMEHYENSPHRRELKDATHKERGHNPLCGDDITLYLKMNGDIIEDASFTGHGCAISQASTSMMIDLIKGKDKKEALRLVQEFIDMIHKKDVNLDELGDAQVLHGVSDFPARVKCALLAWKTLQEIL
>NC_010321.1|WP_003869923.1|138221_139442_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012268884.1|141548_142769_-|IS110-family-transposase
MDLVYSHVCGLDVHKKSVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_009052111.1|142907_143636_+|peptidase-E
MKKVVAIGGGEISKFETFKIDEEIVKLTDKAKPKALFVPTASGEPEAYCDNFDFVYGKMLGCETDILFLIKDDPDSSQIEKKISWADLIYVGGGNTKRMMEIWRSKGVDKMLIDAYQRGTVLSGLSAGAICWFKYGFSDSQRFENQENWHYTKVEGLGLFDAILCPHLNEENRRELFEKFMIDFEGVGIGLENGCAIEIVDDTFKIINSFENAHAYVFRRSENKLFVDEIRHRDYIPFNLLI
>NC_010321.1|WP_003867574.1|143964_144462_+|CRISPR-associated-protein-Cas4
MEFEVTGALMQSYTICKRQVWLMAHQIVPDQEHPYIEIGRLIDENSYQRDRKKIHFENVVLDLVRMEKDNILIGEVKKSSKAEDSAKMQLLFYLYKLKQSGITAKGQLFFPEERKREVVELTPEFEREVIKAIEEIKDIVYKEKPPAFIKIPYCKNCGYKEFCMS
>NC_010321.1|WP_004399636.1|144458_145451_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKTIYIFSDGELKRKDNTLFFEGENGRKFIPVENTSEIMVFGEVSLNKRLLEFLTQSEIILHFFNHYGYYVGSYYPREHLNSGYMILRQAEHYNDESKRLYLAQKFVEGAYKNIRQVLKYYSNRGKDLEDVIYSIEKLGESVDSTSTINELMAIEGNIREYYYKAFDEIIQNPDFKFDFRSKRPPQNFLNTLISFGNSLMYTTTLSEIYKTHLDPRIGFLHATNFRRFSLNLDVSEIFKPIIVDRTIFTLLSKKMVTKEDFEEDAEGLLLKEKGKKVFVQEFEDKLATTIKHRNLSNNVSYRRLIRLELYKLEKHLIEEEQYKPFIAQW
>NC_010321.1|WP_003871087.1|145467_145731_+|CRISPR-associated-endonuclease-Cas2
MFLILVYDVNEKRVNKVLKTCRKYLHWVQNSVLEGEISEANLKKLKIELSRIIDKDEDSVIFYILRTTKYSEREILGLRKGGEDIII
>NC_010321.1|WP_012268885.1|145851_147777_+|FAD-dependent-oxidoreductase
MELTKPIKIGNLSLKNRVVMAPVKTGYATPEGQVTEELIQYYVNRAKGGVGLIVLESAYVDLSGKEIPRQLGIYDDSMVEGLRRLITPLQEAGSKVAVYINHAGRIANPMVTKLPLIAPSSIACPTIGVEPQGIPHEDIKKWQNTYVKAAVRAYEAGADALEIQFGHGYLIHQFLSPHTNKREDEYGGSFENRIRFGMEILDEIKKEIGADFPIIVRISADEFVPGGWALEDAIRLAKILEDKGVAAIDVSLGSSCESGAITLQTLGTQKGLAWEFASKIKKQVNIPVIAVGRINTPELAEEILVSGKADLVALGRPLVADPLFVEKATSGRSKEIRRCAACHQGCLDELRAGRRFGCNFNPSVGKEEEIEIQKAPQPGKKVFIIGAGLAGLEAAYTAAARGHKVYIYEEKGEIGGQVLPGSVPPHKEELKGIVEYYKEVLPKVGVTLNLNHKVTAEEIAKWEADEVVFATGGQPIVPPIPGLKEYGFLTAVEVLRGEKQAGDKVAIIGGGLIGMETADYLSEQGKKVMVIELLEEVARDMGVFEKILIMKRLKERGVEIYVKTRLKEVGKALLVETPEGEKELPLPDTIVLAVGLKPDPSLYEEVSKILPQEKLHVIGDAKEVRKIVHAISEGRNLGLSL
>NC_010321.1|WP_003871085.1|148037_148817_+|MBL-fold-metallo-hydrolase
MKFCSLRSGSSGNAIYINHKDVHILVDAGLSGRTIEKALLNIGINPKSLSAILITHEHKDHIIGAGVLSRRYNIPIYANKATWEVMEKDIKEISEKNKLYFTTGEEFEIGDVKIMPFKKSHDAVEPVGFSFKCGDKKISIATDLGYMTRGVANHLIGSDIVLLEANHDIEMLINGSYPWPLKKRILSNLGHLSNDAAADTLMKLFKMKAIGIAFLGHLSQNNNRPELAFATVTNVLKKSGVKFEVRMALRNIESDLVEI
>NC_010321.1|WP_012268886.1|149271_150684_+|group-II-intron-reverse-transcriptase/maturase
MDSKDMQRLQTTQQRGYPLNREMEFQKTTEVHSISSASEDGRNEVQRYTSKMLEMIVERGNMEAAYKRVVANKGSHGVDGMEVDELLPYLKENWATIKQQLLEGKYKPQPVRRVEISKPDGGVRLLGIPTALDRLIQQAIAQILNRVYNHTFSDSSYGFRPGRSAKDAIKAAEAYINEGYTWVVDMDLEKFFDRVNHDIIMSKLEKRIGDKRVLKLIRRYLESGVMINGIKVSTEEGTPQGGPLSPLLANIMLDELDKELEKRGHKFCRYADDCNIYVKSRSAGNRVMKSIKKFIESKLKLKINEAKSAVDRPWRRKFLGFSFYTKENEVRIRIHEKSIKRFKEKVREITNRNKGISMENRIKRLNQITTGWVNYFGLADAKSIMKTLDEWIRRRLRACIWKQWKKIKTKHDNLVKLGVEEQKAWEYANTRKGYWRISNSPILNKTLTNKYFESIGYKSLSQRYLIVHNS
>NC_010321.1|WP_003867580.1|150923_151364_+|ACT-domain-containing-protein
MGEDGKLYIIREEILSDSLKKTLKVKELLESGKVKTINEAVKQVGISRSAFYKYRDYVFPFSKFSKGKIITLSMVLDHMPGVLSSILDVVANARGNVVTINQSMPSMGVASVTISIDTQYMEMSLENFLEKLSSQNGVRKIEILGE

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Crispr_ID: NC_010321_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010321_6

139700-141463

Unclear

Consensus_repeat	Method
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder

26 spacers

cas3,cas5,cas7,cas8b1,cas6,cas4,cas1,cas2,RT

The CRISPR arrays of NC_010321_6

>merge|NC_010321|6|139700-141463|CRT,PILER-CR,CRISPRCasFinder
GCGGCATGGGAGTCTATAAGGAATTGAAACCCTATCAGCTCCGGTGGCACCCCAAACGCAATAGCGTTTTTAGCCTACCTATAAGGAATTGAAACGATAGCCTTCAGCTATTAACTTTGCCGCTTCCAATTGGTTTTTAGCCTACCTATAAGGAATTGAAACGCTGGTGCTTATTATTGGAAAGGATATAAACAAGCAGTTTTTAGCCTACCTATAAGGAATTGAAACCGCTGTCGTCTTTGTTAAAGGACCTGTACCCTGCAGTTTTTAGCCTACCTATAAGGAATTGAAACAGATATTGTTCAATATTGCATTTATCTCCGCTTCGCTTGTTTTTAGCCTACCTATAAGGAATTGAAACTGTAGAAAATGTCAAAAAACATCAAAAAGGAGGTGTGGTTTTTAGCCTACCTATAAGGAATTGAAACAGTAAATACGGGAACAGAAGCAGCACCCGTGTGGAGTTTTTAGCCTACCTATAAGGAATTGAAACCATTGCCACTACTTGCAGCAGCAGGAGCATCTATAAGTTTTTAGCCTACCTATAAGGAATTGAAACCGTAGAAATAGACCCACCATTTCATCCAGACACACACGTTTTTAGCCTACCTATAAGGAATTGAAACCTGATTGAGTACTAGGGAGGGAGAGAGATGTATCCGTTTTTAGCCTACCTATAAGGAATTGAAACAGCGCTTGAGGATGCATACATGAATAATACAATTTTAGTTTTTAGCCTACCTATAAGGAATTGAAACCGCCCAAAATGGCGCTTAAAACGGCTGCAAATTTGTCGTTTTTAGCCTACCTATAAGGAATTGAAACCCAGCCTGTAATGCAGGGTCGCCTACAAATCCGACGTGTTTTTAGCCTACCTATAAGGAATTGAAACTTCTTTAGATATACTTAAAAGCAATGTAGAGAAAGGTGGTTTTTAGCCTACCTATAAGGAATTGAAACCGAGTGAAAAGATGATACCATGTCGCTTTGAAATGAGGTTTTTAGCCTACCTATAAGGAATTGAAACTCCCTAGTAGTTTAGCCATATCAGCTTGTTTTAAAGTTTTTAGCCTACCTATAAGGAATTGAAACAGCTCTTTCATTAATTTTGCAGCTTTGTCTGTCGGAGTTTTTAGCCTACCTATAAGGAATTGAAACTTGCCAAGCTGTTTTGCTAATTTGCTCATTTTTGCCGTTTTTAGCCTACCTATAAGGAATTGAAACTCGATATAATAGCTCTAAACGTTTGGCTTTGCTTTGTGTTTTTAGCCTACCTATAAGGAATTGAAACATATCCTCGCCAGATACACATTGCTCGCTAACATACAGGCGTTTTTAGCCTACCTATAAGGAATTGAAACTAACGCAGACGTGGGAGGTTGCCGTGGATTCGGTTGGTTTTTAGCCTACCTATAAGGAATTGAAACTCATAATCTATCAAACCGCTTGCTATTGCAAGCATGAGTTTTTAGCCTACCTATAAGGAATTGAAACACATTGTTTGTAGTTTTGGTATGTTCTGTTGTATACGTTTTTAGCCTACCTATAAGGAATTGAAACTATCATTCCAACTACCAACTTTTGTTAAATAATATTCTCGTTTTTAGCCTACCTATAAGGAATTGAAACTATGCTGCATACGTCGAATACGGCACAAAAAAGATGGGTTTTTAGCCTACCTATAAGGAATTGAAACCCATGTTGGTTTTACGCTCAATCTCGGTTACGTAGAAAGTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|6|6|139700-141463|CRT
GCGGCATGGGAGTCTATAAGGAATTGAAAC	CCTATCAGCTCCGGTGGCACCCCAAACGCAATAGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GATAGCCTTCAGCTATTAACTTTGCCGCTTCCAATTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCTGGTGCTTATTATTGGAAAGGATATAAACAAGCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCTGTCGTCTTTGTTAAAGGACCTGTACCCTGCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGATATTGTTCAATATTGCATTTATCTCCGCTTCGCTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTAGAAAATGTCAAAAAACATCAAAAAGGAGGTGTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTAAATACGGGAACAGAAGCAGCACCCGTGTGGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATTGCCACTACTTGCAGCAGCAGGAGCATCTATAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGTAGAAATAGACCCACCATTTCATCCAGACACACAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CTGATTGAGTACTAGGGAGGGAGAGAGATGTATCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCGCTTGAGGATGCATACATGAATAATACAATTTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCCCAAAATGGCGCTTAAAACGGCTGCAAATTTGTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAGCCTGTAATGCAGGGTCGCCTACAAATCCGACGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTCTTTAGATATACTTAAAAGCAATGTAGAGAAAGGTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGAGTGAAAAGATGATACCATGTCGCTTTGAAATGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCCCTAGTAGTTTAGCCATATCAGCTTGTTTTAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTCTTTCATTAATTTTGCAGCTTTGTCTGTCGGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGCCAAGCTGTTTTGCTAATTTGCTCATTTTTGCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCGATATAATAGCTCTAAACGTTTGGCTTTGCTTTGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATATCCTCGCCAGATACACATTGCTCGCTAACATACAGGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAACGCAGACGTGGGAGGTTGCCGTGGATTCGGTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCATAATCTATCAAACCGCTTGCTATTGCAAGCATGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACATTGTTTGTAGTTTTGGTATGTTCTGTTGTATAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TATCATTCCAACTACCAACTTTTGTTAAATAATATTCTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TATGCTGCATACGTCGAATACGGCACAAAAAAGATGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCATGTTGGTTTTACGCTCAATCTCGGTTACGTAGAAA
GTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|6|6|139765-141395|PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GATAGCCTTCAGCTATTAACTTTGCCGCTTCCAATTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCTGGTGCTTATTATTGGAAAGGATATAAACAAGCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCTGTCGTCTTTGTTAAAGGACCTGTACCCTGCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGATATTGTTCAATATTGCATTTATCTCCGCTTCGCTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTAGAAAATGTCAAAAAACATCAAAAAGGAGGTGTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTAAATACGGGAACAGAAGCAGCACCCGTGTGGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATTGCCACTACTTGCAGCAGCAGGAGCATCTATAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGTAGAAATAGACCCACCATTTCATCCAGACACACAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CTGATTGAGTACTAGGGAGGGAGAGAGATGTATCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCGCTTGAGGATGCATACATGAATAATACAATTTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCCCAAAATGGCGCTTAAAACGGCTGCAAATTTGTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAGCCTGTAATGCAGGGTCGCCTACAAATCCGACGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTCTTTAGATATACTTAAAAGCAATGTAGAGAAAGGTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGAGTGAAAAGATGATACCATGTCGCTTTGAAATGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCCCTAGTAGTTTAGCCATATCAGCTTGTTTTAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTCTTTCATTAATTTTGCAGCTTTGTCTGTCGGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGCCAAGCTGTTTTGCTAATTTGCTCATTTTTGCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCGATATAATAGCTCTAAACGTTTGGCTTTGCTTTGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATATCCTCGCCAGATACACATTGCTCGCTAACATACAGGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAACGCAGACGTGGGAGGTTGCCGTGGATTCGGTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCATAATCTATCAAACCGCTTGCTATTGCAAGCATGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACATTGTTTGTAGTTTTGGTATGTTCTGTTGTATAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TATCATTCCAACTACCAACTTTTGTTAAATAATATTCTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TATGCTGCATACGTCGAATACGGCACAAAAAAGATGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC

>NC_010321|6|6|139765-141463|CRISPRCasFinder
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GATAGCCTTCAGCTATTAACTTTGCCGCTTCCAATTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCTGGTGCTTATTATTGGAAAGGATATAAACAAGCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCTGTCGTCTTTGTTAAAGGACCTGTACCCTGCA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGATATTGTTCAATATTGCATTTATCTCCGCTTCGCTT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGTAGAAAATGTCAAAAAACATCAAAAAGGAGGTGTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGTAAATACGGGAACAGAAGCAGCACCCGTGTGGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CATTGCCACTACTTGCAGCAGCAGGAGCATCTATAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGTAGAAATAGACCCACCATTTCATCCAGACACACAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CTGATTGAGTACTAGGGAGGGAGAGAGATGTATCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCGCTTGAGGATGCATACATGAATAATACAATTTTA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGCCCAAAATGGCGCTTAAAACGGCTGCAAATTTGTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCAGCCTGTAATGCAGGGTCGCCTACAAATCCGACGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTCTTTAGATATACTTAAAAGCAATGTAGAGAAAGGTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CGAGTGAAAAGATGATACCATGTCGCTTTGAAATGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCCCTAGTAGTTTAGCCATATCAGCTTGTTTTAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCTCTTTCATTAATTTTGCAGCTTTGTCTGTCGGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTGCCAAGCTGTTTTGCTAATTTGCTCATTTTTGCC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCGATATAATAGCTCTAAACGTTTGGCTTTGCTTTGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATATCCTCGCCAGATACACATTGCTCGCTAACATACAGGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TAACGCAGACGTGGGAGGTTGCCGTGGATTCGGTTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TCATAATCTATCAAACCGCTTGCTATTGCAAGCATGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACATTGTTTGTAGTTTTGGTATGTTCTGTTGTATAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TATCATTCCAACTACCAACTTTTGTTAAATAATATTCTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TATGCTGCATACGTCGAATACGGCACAAAAAAGATGG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCATGTTGGTTTTACGCTCAATCTCGGTTACGTAGAAA
GTTTTTAGCCTACCTATCCTGAAAATAGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	unknown	unknown	gnl\|CDD\|153240
NC_010321.1\|WP_003867580.1\|150923_151364_+\|ACT-domain-containing-protein	unknown	unknown	gnl\|CDD\|179848
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268886.1\|149271_150684_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003871085.1\|148037_148817_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293819
NC_010321.1\|WP_012268887.1\|151376_152633_+\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09730_cas8b1_CAS-I-B	gnl\|CDD\|187861
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_010321.1\|WP_012268885.1\|145851_147777_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274912

Protein	Function_ID	Function_description	E-value
NC_010321.1\|WP_012268884.1\|141548_142769_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	2.8809e-41
NC_010321.1\|WP_004399636.1\|144458_145451_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	2.64608e-180
NC_010321.1\|WP_009052111.1\|142907_143636_+\|peptidase-E	gnl\|CDD\|153240	cd03146, GAT1_Peptidase_E, Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E. This group contains proteins similar to the aspartyl dipeptidases Salmonella typhimurium peptidase E and Xenopus laevis peptidase E. In bacteria peptidase E is believed to play a role in degrading peptides generated by intracellular protein breakdown or imported into the cell as nutrient sources. Peptidase E uniquely hydrolyses only Asp-X dipeptides (where X is any amino acid), and one tripeptide Asp-Gly-Gly. Peptidase E is believed to be a serine peptidase having a Ser-His-Glu catalytic triad which differs from the Cys-His-Glu catalytic triad typical of GATase1 domains by having a Ser in place of the reactive Cys at the nucleophile elbow. Xenopus PepE is developmentally regulated in response to thyroid hormone and, it is thought to play a role in apoptosis during tail reabsorption.	1.63934e-66
NC_010321.1\|WP_003867580.1\|150923_151364_+\|ACT-domain-containing-protein	gnl\|CDD\|179848	PRK04435, PRK04435, ACT domain-containing protein.	4.00304e-77
NC_010321.1\|WP_003869923.1\|138221_139442_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268886.1\|149271_150684_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	0
NC_010321.1\|WP_012268882.1\|117496_118408_+\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	8.54792e-93
NC_010321.1\|WP_004399630.1\|114957_115713_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	8.76406e-41
NC_010321.1\|WP_003867574.1\|143964_144462_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	6.26269e-66
NC_010321.1\|WP_003869923.1\|129769_130990_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003871085.1\|148037_148817_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293819	cd07733, YycJ-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis YycJ and related proteins; MBL-fold metallo hydrolase domain. Includes the uncharacterized Bacillus subtilis YycJ protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.17177e-57
NC_010321.1\|WP_012268887.1\|151376_152633_+\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NC_010321.1\|WP_003869923.1\|128110_129331_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_003869923.1\|135695_136916_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268881.1\|115732_117496_+\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|187861	cd09730, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family.	4.21073e-159
NC_010321.1\|WP_003871404.1\|118420_119134_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.16445e-42
NC_010321.1\|WP_003871087.1\|145467_145731_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	8.0037e-34
NC_010321.1\|WP_003869923.1\|124977_126198_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012268883.1\|119117_121472_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.27175e-45
NC_010321.1\|WP_012268885.1\|145851_147777_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|274912	TIGR03997, NADH:flavin_oxidoreductase, mycofactocin system FadH/OYE family oxidoreductase 2. The yeast protein called old yellow enzyme and FadH from Escherichia coli (2,4-dienoyl CoA reductase) are enzymes with 4Fe-4S, FMN, and FAD prosthetic groups, and interact with NADPH as well as substrate. Members of this related protein family occur in the vicinity of the putative mycofactocin biosynthesis operon in a number of Actinobacteria such as Frankia sp. and Rhodococcus sp., in Pelotomaculum thermopropionicum SI (Firmicutes), and in Geobacter uraniireducens Rf4 (Deltaproteobacteria). The function of this oxidoreductase is unknown.	2.09042e-149

>NC_010321.1|WP_003869923.1|138221_139442_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|135695_136916_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|129769_130990_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|128110_129331_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_003869923.1|124977_126198_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012268883.1|119117_121472_+|CRISPR-associated-helicase/endonuclease-Cas3
MSSFSELYSHPDKFLEDHLINTSKIIRSYFNEKKVAIIDKETFLKTATIISLCHDFGKATNYFQKYLFTENEKERNKLKTMEEMHHSLLSAVVAFYLVKNEINAQDRKGILFPFIAFLIVKNHHGDLKNVFNEVILDDKELEVLKKQLNSIDDEKLQVLNGKLRNAGLNENLTKSAINDYIDSINSELRKIKRELRRLKEEQDVSIYLLLNFLFSLLVDADKTEVVVGIDNIKRPEIKFEEQLVKEYKASFPDKESKINLLREEAYKEVLEKDIDIKQKIMSINLPTGLGKTLTTIAFAMKLWAKLYKETGVKYRIIYSLPFLSIIEQNSNVLEDLLRYNGIQPDTEIILKHHHLSDIRYTKNNTEFEDEQAKILIEGWNSEIIITTFVQFFHTLVSEKNKTLRKFHRLANSIIILDEVQSIPFKYWLLTKELLKAVANELNSYIIFVTATQPLIFREEEIYPLVAKTKYFTQMDRVEIIPKLSRDITLEELSEMFDLNDGKSYLFILNTIKSAQQFYNILRAKIPNDEIIYMSTHVVPMERMERIEKIKEGKIRFAVTTQLVEAGVDIDFDVVVRDIAPLDSINQSAGRCNRNWRGKGEVYVVSLIDEKGQKYSKYVYDKILLGITREILSKYDTIKEQELLKIIEKYYQEVSERMSSNEGRELLDAIYTLRYDSEDGNMCISKFELIEDDYYKVDAFIELNDEAKELWHKYVELKDIKNLFERRNIFNRFKADFYKYVISIPATVENMPPDIWGFKYVNYDSLNDYYDKETGFITKGVTSIW
>NC_010321.1|WP_003871404.1|118420_119134_+|type-I-B-CRISPR-associated-protein-Cas5
MKTLVFDVFGDYGHFRKYYTTSSPLTFSFPPPPTVKGMLGAIAGIDKKEYLKVFSEENCKVAIRILNPIKKIRLGLNLINTKGNYWIPYKAKNHEARTQVKTEFVKDAAYRIYFMHKDNDLFEDIVEKIKNRRNVYTLSLGLSEMIADYKFIGVYEAEEIENAEVDILSVLPFQSIVEDKIYFENGKKYFKEKIPAGMNEDRVVLSYEDVLYEVNGQSIKCHVKKCWEVKGEHVIFF
>NC_010321.1|WP_012268882.1|117496_118408_+|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MENVIKNRAEILFLYDVSFANPNGDPVDENKPRIDEETGINIVTDVRLKRTIRDYLAYYKGKEVFIIETRKDNGELRTKKDRIEDFGTNEDIIAKCIDVRLFGATTAVKDKMMILTGPVQFKYGKSLHRVNLMYVKGTTVMPSGEGREQGTFTEKYILPYSLIAFYGIVNENAAINQNIPLTDEDVDLMLEGMWNGTKNLMSGSKIGHMPRLLIEVVYQENNYQIGELEKRIKFVHEMEDEEIRDIQDGKLDITELVAVLKQNQEKIKLIKYIYDDRVTFTCNGEECTLEKALKGLNIQKLQY
>NC_010321.1|WP_012268881.1|115732_117496_+|TIGR02556-family-CRISPR-associated-protein
MITAIKELGEMVLKSQNKTLLDVLIENPNQDGRYSKIIAINFIVKEDEIEYEGIRLEEYDDSKISRYLFTDTGGNAPGYTPAAKITEVPKTFNGKIKNWFNKVLKDKSIKIDEKDRAFLERIKDILEEKSDEIIKEAEKIRGDFPKKEGLSLILKFNVDGEYKYIGDFNVFRDLMLQLDSQKYQKIYAEDKVCSICGQKKDIVFGTVDTYKFYTIDKPGYIAGGFNEKESWKNYPVCAECRLALEEGKRYLENELTFRFYGLEYQLIPNFIIGKEFVRKEVREIFESSERLLSLKREVKKRFIGDEDEILDYLADAEDSMTVNLLFLRKSNSAERILLLIEDVFPSHLREIFNAKEQVDKIFGNSFTFKNIRSFMSKSDSNKRDNDLDGYFLDITDRIFRGRPVDLGFLYNLIMKKIREEFVKDGYYKAATADGLMTIAFLEKMKLIKMEVIPMEERIFDSFFAKYGPTFEMPLKRGLVLLGALTELLLRKQYSDREAKPFMKNLKGLKMDEKDIKGLLPKVQNKLEEYDSFEKGKRLLAKEASNYLLLAGDNWNMSVDEINFYFACGINLADELTSIIYKKEGEEK
>NC_010321.1|WP_004399630.1|114957_115713_+|CRISPR-associated-endoribonuclease-Cas6
MRITLEFVGEKNLVLPIHYNYIVQGFLYDLMGDSEFAAFLHDEGFQYEKRKFKLFTFSRIEGEFKILTDSKGQKKISIKPPFKFTVASPLDEFIFDISKNALKKEYCHFNGQKFILNSLNIDNPPVFKNKARIKFISPVVMYTTLKDGDIKYTYYYSPWDEKFSPLLLNNLLKKYELVYKIKAEDPYFKLYPLSEKEDRRYSKMIKYKNVYVKGWMGIYDVESSPELLELAYYTGLGAKNSQGFGCFEIIG
>NC_010321.1|WP_012268884.1|141548_142769_-|IS110-family-transposase
MDLVYSHVCGLDVHKKSVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_009052111.1|142907_143636_+|peptidase-E
MKKVVAIGGGEISKFETFKIDEEIVKLTDKAKPKALFVPTASGEPEAYCDNFDFVYGKMLGCETDILFLIKDDPDSSQIEKKISWADLIYVGGGNTKRMMEIWRSKGVDKMLIDAYQRGTVLSGLSAGAICWFKYGFSDSQRFENQENWHYTKVEGLGLFDAILCPHLNEENRRELFEKFMIDFEGVGIGLENGCAIEIVDDTFKIINSFENAHAYVFRRSENKLFVDEIRHRDYIPFNLLI
>NC_010321.1|WP_003867574.1|143964_144462_+|CRISPR-associated-protein-Cas4
MEFEVTGALMQSYTICKRQVWLMAHQIVPDQEHPYIEIGRLIDENSYQRDRKKIHFENVVLDLVRMEKDNILIGEVKKSSKAEDSAKMQLLFYLYKLKQSGITAKGQLFFPEERKREVVELTPEFEREVIKAIEEIKDIVYKEKPPAFIKIPYCKNCGYKEFCMS
>NC_010321.1|WP_004399636.1|144458_145451_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKTIYIFSDGELKRKDNTLFFEGENGRKFIPVENTSEIMVFGEVSLNKRLLEFLTQSEIILHFFNHYGYYVGSYYPREHLNSGYMILRQAEHYNDESKRLYLAQKFVEGAYKNIRQVLKYYSNRGKDLEDVIYSIEKLGESVDSTSTINELMAIEGNIREYYYKAFDEIIQNPDFKFDFRSKRPPQNFLNTLISFGNSLMYTTTLSEIYKTHLDPRIGFLHATNFRRFSLNLDVSEIFKPIIVDRTIFTLLSKKMVTKEDFEEDAEGLLLKEKGKKVFVQEFEDKLATTIKHRNLSNNVSYRRLIRLELYKLEKHLIEEEQYKPFIAQW
>NC_010321.1|WP_003871087.1|145467_145731_+|CRISPR-associated-endonuclease-Cas2
MFLILVYDVNEKRVNKVLKTCRKYLHWVQNSVLEGEISEANLKKLKIELSRIIDKDEDSVIFYILRTTKYSEREILGLRKGGEDIII
>NC_010321.1|WP_012268885.1|145851_147777_+|FAD-dependent-oxidoreductase
MELTKPIKIGNLSLKNRVVMAPVKTGYATPEGQVTEELIQYYVNRAKGGVGLIVLESAYVDLSGKEIPRQLGIYDDSMVEGLRRLITPLQEAGSKVAVYINHAGRIANPMVTKLPLIAPSSIACPTIGVEPQGIPHEDIKKWQNTYVKAAVRAYEAGADALEIQFGHGYLIHQFLSPHTNKREDEYGGSFENRIRFGMEILDEIKKEIGADFPIIVRISADEFVPGGWALEDAIRLAKILEDKGVAAIDVSLGSSCESGAITLQTLGTQKGLAWEFASKIKKQVNIPVIAVGRINTPELAEEILVSGKADLVALGRPLVADPLFVEKATSGRSKEIRRCAACHQGCLDELRAGRRFGCNFNPSVGKEEEIEIQKAPQPGKKVFIIGAGLAGLEAAYTAAARGHKVYIYEEKGEIGGQVLPGSVPPHKEELKGIVEYYKEVLPKVGVTLNLNHKVTAEEIAKWEADEVVFATGGQPIVPPIPGLKEYGFLTAVEVLRGEKQAGDKVAIIGGGLIGMETADYLSEQGKKVMVIELLEEVARDMGVFEKILIMKRLKERGVEIYVKTRLKEVGKALLVETPEGEKELPLPDTIVLAVGLKPDPSLYEEVSKILPQEKLHVIGDAKEVRKIVHAISEGRNLGLSL
>NC_010321.1|WP_003871085.1|148037_148817_+|MBL-fold-metallo-hydrolase
MKFCSLRSGSSGNAIYINHKDVHILVDAGLSGRTIEKALLNIGINPKSLSAILITHEHKDHIIGAGVLSRRYNIPIYANKATWEVMEKDIKEISEKNKLYFTTGEEFEIGDVKIMPFKKSHDAVEPVGFSFKCGDKKISIATDLGYMTRGVANHLIGSDIVLLEANHDIEMLINGSYPWPLKKRILSNLGHLSNDAAADTLMKLFKMKAIGIAFLGHLSQNNNRPELAFATVTNVLKKSGVKFEVRMALRNIESDLVEI
>NC_010321.1|WP_012268886.1|149271_150684_+|group-II-intron-reverse-transcriptase/maturase
MDSKDMQRLQTTQQRGYPLNREMEFQKTTEVHSISSASEDGRNEVQRYTSKMLEMIVERGNMEAAYKRVVANKGSHGVDGMEVDELLPYLKENWATIKQQLLEGKYKPQPVRRVEISKPDGGVRLLGIPTALDRLIQQAIAQILNRVYNHTFSDSSYGFRPGRSAKDAIKAAEAYINEGYTWVVDMDLEKFFDRVNHDIIMSKLEKRIGDKRVLKLIRRYLESGVMINGIKVSTEEGTPQGGPLSPLLANIMLDELDKELEKRGHKFCRYADDCNIYVKSRSAGNRVMKSIKKFIESKLKLKINEAKSAVDRPWRRKFLGFSFYTKENEVRIRIHEKSIKRFKEKVREITNRNKGISMENRIKRLNQITTGWVNYFGLADAKSIMKTLDEWIRRRLRACIWKQWKKIKTKHDNLVKLGVEEQKAWEYANTRKGYWRISNSPILNKTLTNKYFESIGYKSLSQRYLIVHNS
>NC_010321.1|WP_003867580.1|150923_151364_+|ACT-domain-containing-protein
MGEDGKLYIIREEILSDSLKKTLKVKELLESGKVKTINEAVKQVGISRSAFYKYRDYVFPFSKFSKGKIITLSMVLDHMPGVLSSILDVVANARGNVVTINQSMPSMGVASVTISIDTQYMEMSLENFLEKLSSQNGVRKIEILGE
>NC_010321.1|WP_012268887.1|151376_152633_+|homoserine-dehydrogenase
MKIGLMGLGTVGTGVVHLINQNGKNIEKKIGEKIEIKKILVKDPNKKRTPLAEGKITFDANDILEDEEIDVVVEVMGKEHPALEYIIKALKKGKHVVTANKEVIAVHGKELIKLATENKVSLLYEASVGGGIPIIRPLKQCLAANKIYEIKGILNGTTNYILTEMKEKGFDFEEVLKEAQQKGYAEADPTDDVEGFDAARKLAILSTLAFNKFILPEKIYTKGIKSISKSDIKYAEELGYNVKLIAYAKIDEEDRLEAWVHPVMIKKDNPLNGVNGVFNAILVDGNAVGEVMFYGQGAGMMPTASAVVADIMDVKNHIVIQNGCEDGDLLPIVDTVSKYYIRLIAFDKPGVMSKITGILGDKGISLLSVVQKGVLGDTAEIVLITHIANTGKVFEALEEIQNLKEVECIESVIRVEGE

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Crispr_ID: NC_010321_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010321_7

809146-809344

Orphan

Consensus_repeat	Method
ATAGCTCAGTTGGTAGAGCAACACCCTGCCAAGCTG	PILER-CR

2 spacers

csa3

The CRISPR arrays of NC_010321_7

>merge|NC_010321|7|809146-809344|PILER-CR
ATAGCTCAGTTGGTTAGAGCGCCAGCCTGTCACGCTGGAGGTCGAGGGTTCAAGTCCCTTTTGGGTCGCCAGTTATGCCTCGATAGCTCAGTAGGTAGAGCAAGGGACTGAAAATCCCTGTGTCAGTGGTTCGATTCCACTTCGAGGCACCATTTGTGCGGACATAGCTCAGTTGGTAGAGCATCACCTTGCCAAGGTG

>NC_010321|7|7|809146-809344|PILER-CR
ATAGCTCAGTTGGTTAGAGCGCCAGCCTGTCACGCTG	GAGGTCGAGGGTTCAAGTCCCTTTTGGGTCGCCAGTTATGCCTCG
ATAGCTCAGTAGGTAGAGCAAGGGACTGAAAATCCCT	GTGTCAGTGGTTCGATTCCACTTCGAGGCACCATTTGTGCGGACATAGCTCAGTTGGTAG
AGCATCACCTTGCCAAGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010321.1\|WP_004401892.1\|818756_818954_+\|50S-ribosomal-protein-L35	unknown	unknown	gnl\|CDD\|234676
NC_010321.1\|WP_004401900.1\|818177_818729_+\|translation-initiation-factor-IF-3	unknown	unknown	gnl\|CDD\|234582
NC_010321.1\|WP_003867225.1\|805959_806181_+\|NifU-family-protein	unknown	unknown	gnl\|CDD\|376458
NC_010321.1\|WP_009052585.1\|808052_808937_+\|Hsp33-family-molecular-chaperone-HslO	unknown	unknown	gnl\|CDD\|234643
NC_010321.1\|WP_012269167.1\|816928_817981_+\|chorismate-synthase	unknown	unknown	gnl\|CDD\|235438
NC_010321.1\|WP_157748019.1\|806286_806430_+\|transposase	unknown	unknown	gnl\|CDD\|284650
NC_010321.1\|WP_012269165.1\|813665_815570_+\|threonine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234752
NC_010321.1\|WP_003867223.1\|804238_805012_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|234599
NC_010321.1\|WP_012269161.1\|805441_805906_+\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|224867
NC_010321.1\|WP_003867230.1\|809568_809904_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NC_010321.1\|WP_012269164.1\|812768_813368_+\|DUF445-family-protein	unknown	unknown	gnl\|CDD\|226834
NC_010321.1\|WP_012269163.1\|811807_812686_+\|putative-sporulation-protein-YtxC	unknown	unknown	gnl\|CDD\|378056
NC_010321.1\|WP_009052587.1\|806966_807713_+\|NAD-dependent-protein-deacylase	unknown	unknown	gnl\|CDD\|238704
NC_010321.1\|WP_003867222.1\|802271_803666_+\|dipeptidase-PepV	unknown	unknown	gnl\|CDD\|235988
NC_010321.1\|WP_003867226.1\|806770_806941_+\|small,-acid-soluble-spore-protein,-alpha/beta-type	unknown	unknown	unknown
NC_010321.1\|WP_003867232.1\|811017_811752_+\|hypothetical-protein	unknown	unknown	unknown
NC_010321.1\|WP_012269166.1\|815672_816917_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NC_010321.1\|WP_003867231.1\|810026_810959_+\|response-regulator	unknown	unknown	gnl\|CDD\|226229
NC_010321.1\|WP_009052586.1\|807788_807992_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_010321.1\|WP_003867221.1\|801595_801931_-\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042

Protein	Function_ID	Function_description	E-value
NC_010321.1\|WP_004401892.1\|818756_818954_+\|50S-ribosomal-protein-L35	gnl\|CDD\|234676	PRK00172, rpmI, 50S ribosomal protein L35; Reviewed.	1.04476e-21
NC_010321.1\|WP_004401900.1\|818177_818729_+\|translation-initiation-factor-IF-3	gnl\|CDD\|234582	PRK00028, infC, translation initiation factor IF-3; Reviewed.	8.39937e-90
NC_010321.1\|WP_003867225.1\|805959_806181_+\|NifU-family-protein	gnl\|CDD\|376458	pfam01106, NifU, NifU-like domain. This is an alignment of the carboxy-terminal domain. This is the only common region between the NifU protein from nitrogen-fixing bacteria and rhodobacterial species. The biochemical function of NifU is unknown.	1.63171e-29
NC_010321.1\|WP_009052585.1\|808052_808937_+\|Hsp33-family-molecular-chaperone-HslO	gnl\|CDD\|234643	PRK00114, hslO, Hsp33 family molecular chaperone HslO.	9.02406e-140
NC_010321.1\|WP_012269167.1\|816928_817981_+\|chorismate-synthase	gnl\|CDD\|235438	PRK05382, PRK05382, chorismate synthase; Validated.	0
NC_010321.1\|WP_157748019.1\|806286_806430_+\|transposase	gnl\|CDD\|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	1.95313e-05
NC_010321.1\|WP_003867223.1\|804238_805012_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|234599	PRK00052, PRK00052, prolipoprotein diacylglyceryl transferase; Reviewed.	1.73564e-64
NC_010321.1\|WP_012269161.1\|805441_805906_+\|GAF-domain-containing-protein	gnl\|CDD\|224867	COG1956, COG1956, GAF domain-containing protein [Signal transduction mechanisms].	1.04609e-49
NC_010321.1\|WP_003867230.1\|809568_809904_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.13991e-19
NC_010321.1\|WP_012269164.1\|812768_813368_+\|DUF445-family-protein	gnl\|CDD\|226834	COG4399, COG4399, Uncharacterized protein conserved in bacteria [Function unknown].	6.76401e-19
NC_010321.1\|WP_012269163.1\|811807_812686_+\|putative-sporulation-protein-YtxC	gnl\|CDD\|378056	pfam08812, YtxC, YtxC-like family. This family includes proteins similar to B. subtilis YtxC an uncharacterized protein.	4.38316e-73
NC_010321.1\|WP_009052587.1\|806966_807713_+\|NAD-dependent-protein-deacylase	gnl\|CDD\|238704	cd01413, SIR2_Af2, SIR2_Af2: Archaeal and prokaryotic group which includes Archaeoglobus fulgidus Sir2-Af2, Sulfolobus solfataricus ssSir2, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span. The Sir2 homolog from the archaea Sulfolobus solftaricus deacetylates the non-specific DNA protein Alba to mediate transcription repression.	4.41582e-116
NC_010321.1\|WP_003867222.1\|802271_803666_+\|dipeptidase-PepV	gnl\|CDD\|235988	PRK07318, PRK07318, dipeptidase PepV; Reviewed.	0
NC_010321.1\|WP_012269165.1\|813665_815570_+\|threonine--tRNA-ligase	gnl\|CDD\|234752	PRK00413, thrS, threonyl-tRNA synthetase; Reviewed.	0
NC_010321.1\|WP_012269166.1\|815672_816917_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.24308e-14
NC_010321.1\|WP_003867231.1\|810026_810959_+\|response-regulator	gnl\|CDD\|226229	COG3706, PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms].	2.92295e-43
NC_010321.1\|WP_009052586.1\|807788_807992_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	7.57026e-32
NC_010321.1\|WP_003867221.1\|801595_801931_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.27973e-20

>NC_010321.1|WP_009052585.1|808052_808937_+|Hsp33-family-molecular-chaperone-HslO
MRDYIVRATAYNNKILAIAAFSTQTAQKAKEIHNLTPTTCAALGRALTAVAMMRVMMKGEKDKVTLVIKGDGPIGNIVVVSNYPGIVKGYVGNPTVDLPLSEKGKLDVGKAVGKNGYVTVIKDIGLKEPYVGTVELQTGEIGEDIAYYFYTSEQVPSAVGVGVLVGKEGNVLASGGFIIQLLPNIEEEVVAKVEEALKNISSVTELLRKGYLPEDILNHILGEMGLNILERVDLKYECDCSQERFETAIIALGKEEIKKLIAEGQSVEAVCHFCGKKYLIEESRLKELLRIAEE
>NC_010321.1|WP_009052586.1|807788_807992_+|cold-shock-protein
MVRGKVKWFNAEKGYGFIEREDGTDVFVHYSAIEGDGFKTLEEGQKVEFEVVEATKGPQASKVRKVN
>NC_010321.1|WP_009052587.1|806966_807713_+|NAD-dependent-protein-deacylase
MGDKNLFEKAARLIKQSRKTIVLTGAGISTESGIPDFRSPGRGLWENLDPMEVLSTGVLYNFPEEFYKVGFKILSSMRNAEPNEAHYILSEMEKEGIIFGVITQNIDNLHQKAGSKNVFEVHGNTREGSCLRCGKKVSFEVLEEKVSKKQIPPRCDDCNGVLRPDVVLFGDPMPYAFDLAVKEVKSSDLLIVIGSSLAVSPVNFLPDTVRHLIIINATETPYDYKADVVIREKASYALRNIWDIIKFQ
>NC_010321.1|WP_003867226.1|806770_806941_+|small,-acid-soluble-spore-protein,-alpha/beta-type
MDNEILKLEAAEELGLLEKVKKVGWSKLSAQETGKIGSIVKKKMKLQQEVGKKEKL
>NC_010321.1|WP_157748019.1|806286_806430_+|transposase
MYVCQNCGIVVNGDVNGAVNILRRVSPNLKKDRGRGFLDNPVRIKVS
>NC_010321.1|WP_003867225.1|805959_806181_+|NifU-family-protein
MRERVEEVLELLRPSLQADGGDVELIDVTEDGIVKVRLTGACGGCPFATLTLKEGIERAIKEEIPEVKEVIAV
>NC_010321.1|WP_012269161.1|805441_805906_+|GAF-domain-containing-protein
MEKRKVFDDLLVRIDQMAREIDDMDEFYGEVVKILADNVPYYNWTGFYFMKDGELVIGPYIGRPTEHVRIKVGQGVCGRAVAEKNTIIVDDVTKEDNYLACSLETKSEIVVPIWANGDIIGEIDIDSDDLAAFDEEDKRFLEKVAEIISRKLKK
>NC_010321.1|WP_003867223.1|804238_805012_+|prolipoprotein-diacylglyceryl-transferase
MYIPTISPYAFKIGPIDVHWYGIFMAISIAIGGYYLYRQAMKLNYDEDFLLNLLMIVVISGVVGARLMFVLANYPEWFIKDPVQVLKIYEGGLSWHGAVLGGFLAGLYYCRKKGVRINPLEDFAVLGLSIGNILVRIGNIFNQEVLGRPTEFAFGRWPAQLVGVAMGIILLIRYFYIQKKHMPDGYQFWSFIFYYQLMRGLIEETVRDNPLIWPVYLNEKWGIGFFTLTQLVTPFILILAYWMIRRVLNDPNKQFYN
>NC_010321.1|WP_003867222.1|802271_803666_+|dipeptidase-PepV
MDLNSYIDNMRDDIIKSVQELVRIKSVQDEPKPGMPYGEGIAKALDKALEIAQSLGLKTKNVDGYVGYAEYGEGEEMIGVLGHLDVVPEGDGWTYPPYGAEIHDGKIYGRGTVDDKGPIIAALYGLKAIKDAGLELSRRVRILFGTNEETGSHEIPYYLKHDEAPTMGFTPDAQYPIIYAEKGITMFNVVKDFNKKPSNIVIKYIKGGERPNVVPGFCEAGLKVKEANKKKEIQDKLEAFVKETGYNLKAEEKDEMLVIKSVGVSAHGSLPHLGKNAIMQLFLFLDRIDLEDSDVKDFIHFFATNIGIETNGKTFGIYLKDETGELTFNVGTIQLDESKGVLGLNIRYPVKYKYEDWMNIFENKIKTNGMRIEDMLHQPPLYFPPAHPLIKTLSKVYEEQTGQKAELLAIGGGTYAKEMPNTVAFGPVFPGKPELAHQADEYIEIEDLILNAKIYAHAIYELAK
>NC_010321.1|WP_003867221.1|801595_801931_-|winged-helix-turn-helix-transcriptional-regulator
MAENIYELRAEFFKALSHPTRLKILDVILNEKEICVCEIVNKIGVDQSTISKHLNILKKAGILESKKEGLSVFYKVRFPCMKDYFICIDKTIKCDLVTKVSFIDSSKEKVE
>NC_010321.1|WP_003867230.1|809568_809904_+|thioredoxin-family-protein
MEKIIDIENIEQIIKENDMVFLYFSTQDCGICTSLLPKLEGMLVNYPKIKSFHIPIDEIPLASGKFSVFTVPTVIVYVDGKEAIREARFISMDTLEEKISKYYSLFFEETA
>NC_010321.1|WP_003867231.1|810026_810959_+|response-regulator
MKGRNILIVDDNKLTRKILKDILENAGYGVLEAKDGEEALQIYRNKLPDMVILDIVMPGMNGFDLLRILRKEEENLMLPIILLTSQDNFEEKIKGLELGADDYLVKPFNDKELLFKVNNLFQRIEHNRMANPLTGLRGNIDIKEEIKRRIKENKPYAILYIDLDNFKSYNDYYGFLRGDNVIKLTAKILSDAVNLIGNERDFLGHIGGDDFVIITTPDKAEEMCKYIISRFDEEIKYLYDDEDRKRGYIETIGRTGEKMMFPLVSISIAIVTNEFRDFKNDLEISAVAAELKKKLKTMDGSCYLKDRRKG
>NC_010321.1|WP_003867232.1|811017_811752_+|hypothetical-protein
MSNPFVPHGNFKWVVIDGREREIGDSLSKLGIKVLYTEKCADLYDAISFHPDILLHPLGDREIIVAPNVTPEFIRKLKLIGLKVKIGQTFLKRNYPYDIAYNVARLGNTAFHNFKYTDPVLRESLEKKGVKFLNVKQGYTKCNMAIIDDNSFITSDKGIFEVAVSNGFEALLIEPGGVFLKGFEYGFIGGAMGLIGEKKLAVTGVFNSHKNYEKIIEFLNKKGIEIVYLTFKQIKDIGSIIPLI
>NC_010321.1|WP_012269163.1|811807_812686_+|putative-sporulation-protein-YtxC
MQLFSIGVSKDLKLDAENLKHGLKNLAENGIKIAINSNVCGSVTYYSLKVEDKQGFSNVARIRNYIAEAISDIIVNQIDKRIIKKLINKYYHYFSEDEKEEIEKIAYNILEDDVNKETFKLAKKEQIFVLVRDFLKESDYIDLEGFVNFRLRDFIGELSEVTDKAVDEFLMKKEYNEFIGLLKYFVELQDSKVEILNIIVDKNGKFKLYDENDKPISNDFINEIVAELKDGVISDEDALISTLITIAPKKIFFHSINNMRDNEILETVKKVFNDKVEICYGCELCSKIKCEK
>NC_010321.1|WP_012269164.1|812768_813368_+|DUF445-family-protein
MQFLTRMLFLAFVGAAIGWLTNFVAVKMLFKPLKPVKIFGITLQGLIPKRKYEIAKSIGEIVERELLSFNDLWDRLLTEENRKFLLSNLDLKVKEVTENKLPSFLPKAIKEMISNYIGDIINREVEVFLNSPSNEVVEIISTKLKISEIVEEKIKSFKLEKLEDVVIKIAHSELYMIEIMGGVLGFLIGVLQAIVIQFL
>NC_010321.1|WP_012269165.1|813665_815570_+|threonine--tRNA-ligase
MIIILKDGTQREFEKGMTVYEIAKSISERLAKEAVGGKFNGKVVELNTKIEEDGKLEILTFDDEEGKKIYWHTSSHILAQAVKRLFKDVKLAIGPAIDNGFYYDFDTDRPFTTEDFEAIEQEMNKIIKEDYKLERFVLPKDKAIKLMEGKGEPYKVELIKEIPEGEEISFYKQGEFTDLCAGPHLMSTGMVKTIKLLSVAGAYWKGDEKNKMLQRIYGISFPKKSMLDEYLHMLEEAKKRDHRKLGKELDLFSIHPEGPGFPFFHPKGMIIRNILEDFWRKEHMKHGYQEIKTPIILNEELWRRSGHWDHYKENMYFTEIDGETYAIKPMNCPGAMLVYKSTMHSYRDLPLRLCELGLVHRHELSGVLHGLMRVRSFTQDDAHLFMTPEQVEDEILGVINLVDYFYKIFGFEYFVELSTRPENSMGSDEDWELATNALISALNRVNLPYKVNEGDGAFYGPKIDFHLKDSIGRTWQCGTIQLDFQMPERFELEYIGPDGEKHRPIMLHRVIYGSIERFIGILTEHFAGAFPTWLAPVQVRVLPISDKHYAYAQNVYGRLLENDIRAELDDRNEKVGYKIREAQLQKIPYMLIVGDKEVEQGTVSLRSRKEGDLGAISLSEFIEKILKEIATKAL
>NC_010321.1|WP_012269166.1|815672_816917_+|MFS-transporter
MKKNLEVYKHLKYNIKMNMINGLAWAIGFNMVNPFIGIYAIKLGADDFQVSLLNSLPALMVVIGVIPVTYLINSLKNVHKFAYIVLYIARAFYFLLALAPFFDKEFQPWIVVILVGVMNLPSMAVGMCWQSFMSELIPPEYRSKVFADRNFWTTIVATITVLVTGWLLDKIVFPINYQVIFTVAFIFGLIESYYFSRFHVVKRDLDEAKPGSFYEAFRNMFESKKFIYFNVTSFIYYFAWMMAWPIFTIYKVNFLHANNAWMSIFTIVSSIGSILAFYKWADLSNKRGNGFAVALSALLLGFIPLMWATAKNLYVGAIFDFLGGIAVGGYNMLLLNWLLELLPPTSEKMNYIAVFTLITQISAFIAPMFGMWLYTQMGYVAFMILTGIARIVVSILYFLVANYEDEIKEIEAKQ
>NC_010321.1|WP_012269167.1|816928_817981_+|chorismate-synthase
MRYITAGESHGEALIAVIEGLPSNLLIDEEFINKELKRRQGGYGRGGRMAIEEDKVHVLSGIRNGKTIGSPLTLEIINKDYENWKNKKTPEVTRPRPGHADLAGAIKYNQRDLRNILERSSARETAARVAVGSVAKLLLKELDIYVKSKVLEIGGVKAEEKWRRTIDEAKSKGDTLGGIIEIVIEGVPVGLGSHVQWDRKLDALLAYHVMSVQAIKAVEIGLGFEAARKPGSLVHDEIYYDEERGFYRKTNNAGGIEGGISNGSPIVIKAAMKPIPTLLKPLTSIDINTKEEVKAAYERSDVTAVEAAACVLEAVCAWVIADECLKKFGGDSIEELKKNYDAYLVYVKNF
>NC_010321.1|WP_004401900.1|818177_818729_+|translation-initiation-factor-IF-3
MRFYFFIIFRRCVFINKELQVNEEIRDKEVRLIDQDGKQIGIMSAKEAYKIAQERHLDLVKIAPQANPPVCKLMDFGKYRYELSKREKEAKKKQKIINVKEIRMSPTIEDHDFGVKLKSAIKFLKEGNKVKVTIRFRGREAAHTSLAEDLLKRFANELSEYGVIEKAPNIEGRNLMMVLTPKS
>NC_010321.1|WP_004401892.1|818756_818954_+|50S-ribosomal-protein-L35
MPKMKTHRGAAKRFKVLKSGKVKRSRAYKSHLLTHKNAKRKRRLRKATYLVGADAKNIKRLLPYS

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Crispr_ID: NC_010321_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010321_8

962976-964275

TypeIII

Consensus_repeat	Method
GTTTTTAGCCTACCTATAAGGAATTGAAAC	PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRISPRCasFinder
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CRT

19 spacers

csx20,csx1,cas10,csm3gr7,csx19

The CRISPR arrays of NC_010321_8

>merge|NC_010321|8|962976-964275|PILER-CR,CRISPRCasFinder,CRT
GTTTTTAGCCTACCTATAAGGAATTGAAACGATAAAGATTGGCAAATAACTGTGATGTAAGGTTACGTTTTTAGCCTACCTATAAGGAATTGAAACGCACAAGAAAAACCTGTACAAGCAGGTAACTGGATTGGTTTTTAGCCTACCTATAAGGAATTGAAACTTTGACGTTGTTTCTTGCTCCACTTCTTCTTTTTGCGTTTTTAGCCTACCTATAAGGAATTGAAACAAGGCTGAACTTGAACAATCTGAAGTGAAGTTGGTACAAGTTTTTAGCCTACCTATAAGGAATTGAAACTTATATTGAAATTGACTGGAATTTTAGAGAATTTTACCTGTTTTTAGCCTACCTATAAGGAATTGAAACAAATATGCTTGTACAACTTTATTGATGAGTTCTTGACGTTTTTAGCCTACCTATAAGGAATTGAAACAAAAATTGGACAGCACAAGGACTAAAAACGAGAGAAGTTTTTAGCCTACCTATAAGGAATTGAAACATAAACTTTTTTACGTCTTGCAGTTTCATTTTTACCGTTTTTAGCCTACCTATAAGGAATTGAAACAGCAATTGTACAGAGCACACTCAAAGAAAAAAAAGAGTTTTTAGCCTACCTATAAGGAATTGAAACATTCCGCTTCTCTTAAAAAACTTTTGTGCGGAAAAATGTGTTTTTAGCCTACCTATAAGGAATTGAAACCCGGCATCCGGGCCACCTCCCTGTTACTGTTACTCTCGTTTTTAGCCTACCTATAAGGAATTGAAACTGGGACCACTACTATGAGCTGATAGAATACGACAAAGTTTTTAGCCTACCTATAAGGAATTGAAACATGGGAAGCATTCGTATATTTCGTAGGTTTTGCAATGTTTTTAGCCTACCTATAAGGAATTGAAACAGGTGGGAGAAAGACAACAAAAGCAATGCACTTGCGTTTTTAGCCTACCTATAAGGAATTGAAACGCATTAAAAATTGCCAAACTGTTGAATGAATATGAGGTTTTTAGCCTACCTATAAGGAATTGAAACACACGCCACCCAAAACACAGTAACCACAATTGCAAACGTTTTTAGCCTACCTATAAGGAATTGAAACTGGTACTTAGGCTAACAAAAATGCCGGCCGTATTAACAGTTTTTAGCCTACCTATAAGGAATTGAAACAATTATTGCAGAGGCAATGGCAAAAGGCTTAAGCAAGTTTTTAGCCTACCTATAAGGAATTGAAACATGCGGTGATGGCTTATGAGGATACGTATATTGCGTAGGTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|8|8|962976-964207|PILER-CR
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GATAAAGATTGGCAAATAACTGTGATGTAAGGTTAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCACAAGAAAAACCTGTACAAGCAGGTAACTGGATTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTGACGTTGTTTCTTGCTCCACTTCTTCTTTTTGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGGCTGAACTTGAACAATCTGAAGTGAAGTTGGTACAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTATATTGAAATTGACTGGAATTTTAGAGAATTTTACCT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAATATGCTTGTACAACTTTATTGATGAGTTCTTGAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAAAATTGGACAGCACAAGGACTAAAAACGAGAGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATAAACTTTTTTACGTCTTGCAGTTTCATTTTTACC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCAATTGTACAGAGCACACTCAAAGAAAAAAAAGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTCCGCTTCTCTTAAAAAACTTTTGTGCGGAAAAATGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCGGCATCCGGGCCACCTCCCTGTTACTGTTACTCTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGGACCACTACTATGAGCTGATAGAATACGACAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGGGAAGCATTCGTATATTTCGTAGGTTTTGCAAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGGTGGGAGAAAGACAACAAAAGCAATGCACTTGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCATTAAAAATTGCCAAACTGTTGAATGAATATGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACACGCCACCCAAAACACAGTAACCACAATTGCAAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGTACTTAGGCTAACAAAAATGCCGGCCGTATTAACA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AATTATTGCAGAGGCAATGGCAAAAGGCTTAAGCAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC

>NC_010321|8|7|962976-964275|CRISPRCasFinder
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GATAAAGATTGGCAAATAACTGTGATGTAAGGTTAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCACAAGAAAAACCTGTACAAGCAGGTAACTGGATTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTGACGTTGTTTCTTGCTCCACTTCTTCTTTTTGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGGCTGAACTTGAACAATCTGAAGTGAAGTTGGTACAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTATATTGAAATTGACTGGAATTTTAGAGAATTTTACCT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAATATGCTTGTACAACTTTATTGATGAGTTCTTGAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAAAATTGGACAGCACAAGGACTAAAAACGAGAGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATAAACTTTTTTACGTCTTGCAGTTTCATTTTTACC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCAATTGTACAGAGCACACTCAAAGAAAAAAAAGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTCCGCTTCTCTTAAAAAACTTTTGTGCGGAAAAATGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCGGCATCCGGGCCACCTCCCTGTTACTGTTACTCTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGGACCACTACTATGAGCTGATAGAATACGACAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGGGAAGCATTCGTATATTTCGTAGGTTTTGCAAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGGTGGGAGAAAGACAACAAAAGCAATGCACTTGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCATTAAAAATTGCCAAACTGTTGAATGAATATGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACACGCCACCCAAAACACAGTAACCACAATTGCAAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGTACTTAGGCTAACAAAAATGCCGGCCGTATTAACA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AATTATTGCAGAGGCAATGGCAAAAGGCTTAAGCAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGCGGTGATGGCTTATGAGGATACGTATATTGCGTAG
GTTTTTAGCCTACCTATCCTGAAAATAGTG

>NC_010321|8|7|962976-964275|CRT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GATAAAGATTGGCAAATAACTGTGATGTAAGGTTAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCACAAGAAAAACCTGTACAAGCAGGTAACTGGATTG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTTGACGTTGTTTCTTGCTCCACTTCTTCTTTTTGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAGGCTGAACTTGAACAATCTGAAGTGAAGTTGGTACAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TTATATTGAAATTGACTGGAATTTTAGAGAATTTTACCT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAATATGCTTGTACAACTTTATTGATGAGTTCTTGAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AAAAATTGGACAGCACAAGGACTAAAAACGAGAGAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATAAACTTTTTTACGTCTTGCAGTTTCATTTTTACC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGCAATTGTACAGAGCACACTCAAAGAAAAAAAAGA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATTCCGCTTCTCTTAAAAAACTTTTGTGCGGAAAAATGT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	CCGGCATCCGGGCCACCTCCCTGTTACTGTTACTCTC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGGACCACTACTATGAGCTGATAGAATACGACAAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGGGAAGCATTCGTATATTTCGTAGGTTTTGCAAT
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AGGTGGGAGAAAGACAACAAAAGCAATGCACTTGC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	GCATTAAAAATTGCCAAACTGTTGAATGAATATGAG
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ACACGCCACCCAAAACACAGTAACCACAATTGCAAAC
GTTTTTAGCCTACCTATAAGGAATTGAAAC	TGGTACTTAGGCTAACAAAAATGCCGGCCGTATTAACA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	AATTATTGCAGAGGCAATGGCAAAAGGCTTAAGCAA
GTTTTTAGCCTACCTATAAGGAATTGAAAC	ATGCGGTGATGGCTTATGAGGATACGTATATTGCGTAG
GTTTTTAGCCTACCTATCCTGAAAATAGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010321.1\|WP_012269220.1\|960907_961528_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|380314
NC_010321.1\|WP_012269222.1\|962409_962778_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NC_010321.1\|WP_012269231.1\|975961_978136_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
NC_010321.1\|WP_012269218.1\|959221_960181_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379376
NC_010321.1\|WP_012269229.1\|973959_975369_+\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NC_010321.1\|WP_012269230.1\|975358_975943_+\|TIGR03984-family-CRISPR-associated-protein	csx19	cls001376_csx19_CAS-III-D	gnl\|CDD\|274900
NC_010321.1\|WP_003869923.1\|964360_965581_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_010321.1\|WP_012269221.1\|961527_962283_+\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NC_010321.1\|WP_003867700.1\|955808_956738_+\|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl\|CDD\|224617
NC_010321.1\|WP_012269219.1\|960181_960646_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NC_010321.1\|WP_012269225.1\|967597_968887_+\|TIGR02221-family-CRISPR-associated-protein	csx1	pfam09455_csx1_CAS-III	gnl\|CDD\|187863
NC_010321.1\|WP_012269217.1\|957595_958711_+\|sodium-ion-translocating-decarboxylase-subunit-beta	unknown	unknown	gnl\|CDD\|377182
NC_010321.1\|WP_012268741.1\|958896_959118_+\|hypothetical-protein	unknown	unknown	unknown
NC_010321.1\|WP_012269228.1\|971779_973963_+\|hypothetical-protein	csm3gr7	mkCas0198_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|131722
NC_010321.1\|WP_012269227.1\|970250_971783_+\|hypothetical-protein	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|224272
NC_010321.1\|WP_003867702.1\|957189_957549_+\|sodium-pump-decarboxylase-subunit-gamma	unknown	unknown	gnl\|CDD\|377277
NC_010321.1\|WP_012269224.1\|967184_967595_+\|hypothetical-protein	csx20	xls002255_csx20_CAS-I:CAS-III	unknown
NC_010321.1\|WP_012269226.1\|968940_970254_+\|DUF1887-family-protein	csx1	mkCas0112_csx1_CAS-III	unknown
NC_010321.1\|WP_003867701.1\|956751_957153_+\|methylmalonyl-CoA-epimerase	unknown	unknown	gnl\|CDD\|213772
NC_010321.1\|WP_012269223.1\|966521_966878_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_010321.1\|WP_012269220.1\|960907_961528_+\|nitroreductase-family-protein	gnl\|CDD\|380314	cd02137, MhqN-like, nitroreductase family protein similar to the NAD(P)H nitroreductase MhqN. A diverse subfamily of the nitroreductase family containing uncharacterized proteins; includes nitroreductases MhqN, YodC, YdgI, DrgA. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.	1.52587e-50
NC_010321.1\|WP_012269222.1\|962409_962778_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	5.86706e-44
NC_010321.1\|WP_012269231.1\|975961_978136_+\|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	1.68017e-86
NC_010321.1\|WP_012269229.1\|973959_975369_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	1.27304e-16
NC_010321.1\|WP_003869923.1\|964360_965581_-\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.09297e-41
NC_010321.1\|WP_012269221.1\|961527_962283_+\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	4.34418e-25
NC_010321.1\|WP_003867700.1\|955808_956738_+\|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl\|CDD\|224617	COG1703, ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism].	1.71551e-128
NC_010321.1\|WP_012269219.1\|960181_960646_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.27869e-21
NC_010321.1\|WP_012269225.1\|967597_968887_+\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|187863	cd09732, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as TM1812 family.	2.4271e-78
NC_010321.1\|WP_012269217.1\|957595_958711_+\|sodium-ion-translocating-decarboxylase-subunit-beta	gnl\|CDD\|377182	pfam03977, OAD_beta, Na+-transporting oxaloacetate decarboxylase beta subunit. Members of this family are integral membrane proteins. The decarboxylation reactions they catalyze are coupled to the vectorial transport of Na+ across the cytoplasmic membrane, thereby creating a sodium ion motive force that is used for ATP synthesis.	0
NC_010321.1\|WP_012269218.1\|959221_960181_-\|hypothetical-protein	gnl\|CDD\|379376	pfam13800, Sigma_reg_N, Sigma factor regulator N-terminal. This domain is found near the N-terminus of a sigma factor regulator. The N-terminus is responsible for interaction with the sigma factor.	3.36458e-25
NC_010321.1\|WP_012269228.1\|971779_973963_+\|hypothetical-protein	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	6.79483e-16
NC_010321.1\|WP_012269227.1\|970250_971783_+\|hypothetical-protein	gnl\|CDD\|224272	COG1353, COG1353, Predicted CRISPR-associated polymerase [Defense mechanisms].	0.000182261
NC_010321.1\|WP_003867702.1\|957189_957549_+\|sodium-pump-decarboxylase-subunit-gamma	gnl\|CDD\|377277	pfam04277, OAD_gamma, Oxaloacetate decarboxylase, gamma chain.	2.90064e-14
NC_010321.1\|WP_003867701.1\|956751_957153_+\|methylmalonyl-CoA-epimerase	gnl\|CDD\|213772	TIGR03081, Methylmalonyl-CoA_epimerase_mitochondrial, methylmalonyl-CoA epimerase. Members of this protein family are the enzyme methylmalonyl-CoA epimerase (EC 5.1.99.1), also called methylmalonyl-CoA racemase. This enzyme converts (2R)-methylmalonyl-CoA to (2S)-methylmalonyl-CoA, which is then a substrate for methylmalonyl-CoA mutase (TIGR00642). It is known in bacteria, archaea, and as a mitochondrial protein in animals. It is closely related to lactoylglutathione lyase (TIGR00068), which is also called glyoxylase I, and is also a homodimer.	4.01651e-60
NC_010321.1\|WP_012269230.1\|975358_975943_+\|TIGR03984-family-CRISPR-associated-protein	gnl\|CDD\|274900	TIGR03984, hypothetical_protein_FrEUN1fDRAFT_5778, CRISPR-associated protein, TIGR03984 family. Members of this protein family are found exclusively in CRISPR-containing organisms, in operon contexts with RAMP (repeat-associated mystery protein) proteins also linked to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats).	3.8834e-57

>NC_010321.1|WP_012269222.1|962409_962778_+|large-conductance-mechanosensitive-channel-protein-MscL
MLKGFKEFIMRGNVLDLAVAVIIGSTFNKVVNSLVVDVLTPLIGAIFGAPDFSAIKLGPIAIGNFLNAVVNFVIVAAAIYFFIVAPMNAIKRRKPKEKEQTPPEPSEEVKILREILEVLKEK
>NC_010321.1|WP_012269221.1|961527_962283_+|sulfite-exporter-TauE/SafE-family-protein
MKNYILILMASILAGATNSIAGGGTLITFPALVWVGINPLAANMTNTVALWTGSVTGAWGFKERLSQTKELLKFLTLPSLLGGILGAYLLMITPHKVFNFVVPFLVLFATVILALNDRINKFNLDSEEGREKKSLVFVFILQFLTSLYGGYFAAGIGILMLATLGIAGITDIHTANGIKNVLSLFINITSGLVLLFSGKVVWPFAIILMIGFALGGYLGAKISQKFDSKKVKSFVILWGIILAIVFWIRGV
>NC_010321.1|WP_012269220.1|960907_961528_+|nitroreductase-family-protein
MKECQKLITERRSITFFDPTKEISDDFIKEVLEVAATAPSANNLQPWEVIVVKDKEKKKILKEICFNQQKVEDASAVIVLIANPKAAFEHIDRVLDSSIELGYIPKERRESAKERVLEVWKDMEQAKRKSIRDTALFAMNIMIVARVYGLETHPMDGFNEEKMKEFLGIDAEKIVPMIIAIGYKDPSKELLPRAYRFKFEEFGEIV
>NC_010321.1|WP_012269219.1|960181_960646_-|sigma-70-family-RNA-polymerase-sigma-factor
MWQDLYKAAFYYLLKLGVPQADAEDIAQEALLSTYLNLDGIQEGKLKAYVLTAARNKYTDYLRKTKKDMTVSIIDVFPQSTFSEFQQIENKEVIKKAVNRLTLNEQKLFYLKFILEMSNEEISSYLKTNSNTEKTMVWRLRKKLKEYLKEEEKS
>NC_010321.1|WP_012269218.1|959221_960181_-|hypothetical-protein
MGSDLNKPISDISFDEKAFLRKARFKSILRIIIISLIIAIGVFVLTFIIPEMMLQNQENRIDSFYPDIVKFTEPNTFAISGESYNVRLFGRQKEYYLLRLIGNKPYPAGIVTVDFDIWGGEQFQGNKSFCVVETDHIIPYSEISTVIPEGTKEYLAPYAVPKLKFYNPVVKYDKVIREFDVLKNIPNDNLVEMALSFYRPLTFIEIKTIIPEDLKLMWGAVLVFEENDYKEKNYLAERLVGNPYIDSHDGEKEFLKQLEQLSNLQSYSSTNLKRTVNFLKEKGIKYYGVVVVGHPESLQKLSSNSIIRGAVLGIVTTPY
>NC_010321.1|WP_012268741.1|958896_959118_+|hypothetical-protein
MKRGYIHATDRLGNESDFPIMGISIAVVNNSNRKFSDIDEISRIASQIKMECKKYEKSHYIIESLEKGKQAVI
>NC_010321.1|WP_012269217.1|957595_958711_+|sodium-ion-translocating-decarboxylase-subunit-beta
MFEAIINFLKTTGYFNVTLSQLIMIIIAFVLMYLAIVKKYEPLLLVPISFGMLLANIPEAGLMEEGGFLYWIYQGVKLGIYPPLIFMGVGAMTDFGPLISNPKSLLLGAAAQLGIFITFLGARLLGFDAKEASSIGIIGGADGPTAIFVTSKLAPHLLGAVAVAAYSYMALVPIIQPSIMRLLTTKKERTVVMEQLRPVSKTEKIIFPIIITVLASFLVPPATPLIGSLMLGNLFRESGVVDRLSKAVQNELMNILTIFIGLSVGATASGDNFLRLETIEIIILGLIAFAGGTAGGVLFGKLMYLLSGGKVNPLIGSAGVSAVPMAARMSQKVAQEEMPGNFVLMHAMGPNVAGVIGSAIAAGVLLSLYGG
>NC_010321.1|WP_003867702.1|957189_957549_+|sodium-pump-decarboxylase-subunit-gamma
MIEALSTTVLGFGITLIFLYLLSLILDLMRVVFYKKDKKEPKILPSREQEKTKFQEDETEEDEGELIAVITSAILACSQKPADEIKIRLIRRINQRTPIWAMESRLNLMKHQQHLRSLR
>NC_010321.1|WP_003867701.1|956751_957153_+|methylmalonyl-CoA-epimerase
MNILKIDHIGIAVNSIEEASKIYTELLGLEMHGVEEVAEQKVKVAFIPVGESEVELLESTDPEGPIARFIEKNGEGVQHIAFRVEDIEKALEELKQKGVRLIDEKPRYGAGGAKIAFIHPKATKGVLIELCER
>NC_010321.1|WP_003867700.1|955808_956738_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MDLADRVLKKDKRAVARLITLIERESPEATEALKQLYKYTGNSFVIGITGPPGAGKSSLVNELAKKIRAKGKTVGIIAVDPTSPFTGGALLGDRIRMQDLTLDDGIFIRSMGSRGSLGGIAKAAYDAVKVLDAFGMDYIIIETVGVGQSEIDIVKLADTVVLVLVPGLGDDVQAIKAGIMEIADIFAVNKSDREGADRLVTEIEMMLDLSQKQFDFRPPVVKTVAVTGEGIDTLERRIREHLDYLSKNGILEQKRRAKVREEFMELLKDHITRLILQKNSPKIDMLLQDISKKAVDPYTALDILTREIL
>NC_010321.1|WP_003869923.1|964360_965581_-|IS110-family-transposase
MDLVYSHVCGLDVHKKNVVACIITPEGKEIRTFSTMTDDLIALKEFIKAKGCSVVAMESTGSYWKPIYNLLELESIKILLVNAKHIKNVPGRKTDVKDAEWIASLLQHGLLQGSFVPDREQRELRELVRYRKSLIEEKSRELNRIQKVLEGANIKLSSVVSDINGASSRSILEAIINGEENPETLAELSQGKLKNKMDELKRALKGLINHHQRMLLEIQLRHIDYLDEEIAKLDEEIKNRMLPFEKDLALLDTIPGVGRRTAEQIIAEIGTNMEQFPSAAHLCSWAGLCPGHNESAGKQKSARTRKGNQKLRSSLIEAARAASRAKDTYLSSQYHRIAARRGANRAAVAVAHSILIIVYHILKQKQPYIELGPTYYEEKKRNMIIRQSLKKLESLGLKVTVESAVS
>NC_010321.1|WP_012269223.1|966521_966878_+|hypothetical-protein
MIALLNLCNFETPIQSLEEIKNNIELLEENVNDANYEIVKQLQEFVNGQIDLGEKIVDAYIAFKENRNNANAQRINELINQFNEKTAKKNNIIVEILKKANMPYTIDDNGTIHYQYIP
>NC_010321.1|WP_012269224.1|967184_967595_+|hypothetical-protein
MKQIDLKKMFLVFSHQLTDFQKEDARLNLGVNEFIYLPDNLKIQWLDISPYDDSLTFHLQDLINWLKINARKGDYVLVQGDFGATFLIVDFCLKNDLIPVYSTTKREIISEIKNGENIKVSRLFTHVRFRKYERWI
>NC_010321.1|WP_012269225.1|967597_968887_+|TIGR02221-family-CRISPR-associated-protein
MAIKFFSFLGTGAYTKCKYKFDNIESDSSCYVQEALIDNLLKKGVNLESVFIFKTEEATIANWSKNKKYPSDPGLKQVLDKYNGKPSINYVDIPSGQNENELWEIFDKVLEQIDKGDEIIFDITHSFRSIPMLALIILNYAKFIKKCEIRGIYYGAIEAVGKEIKDIEESDIAPIFDLTPFVRLLDWTVGIDRFIETGDARYINYLMKLGTKELHLKGMKDERNILSNFAQKLENYTRNVATCRGKEISKGGLELKNILGDAVSIADKTYIKPMKPVIDRLNDRFINFSNDENKNMIEIVKWCSEHNLIQQGFTILEEGIVNFFCEKFGFDKNNIKEREIIENATYIKHYSLPKDRWKKTAFENEAVIYNLLSKLNEENYKNLIKVLYEEIKPLRNDINHAGYKENDMKAEKFEDKLNELIDKVEKYIV
>NC_010321.1|WP_012269226.1|968940_970254_+|DUF1887-family-protein
MNEKVLVLIVGTNPLPNYVVGSHLKEKYDKFVLIYSEKNDKINQNSTYDYAKKLKEHLNLNDKCIFLPLSDVSNSEKIINDLREKFPSEDFVEVHLNYTGGTKTMVVHIYNFLKEKFKNNKIKFEGSYLDARDYKLVYDYSEEAISLKDTIKIDINTLLSIHLYEDIHFEFYDTYSYKQKFVDSFDKISQEIEKAIKDDKGEDFVKWLEDPFRKIFKGENKLLEKTAKFKKHIEKLLKDNDSSPIVKFNEKTPQFIWDILNAFPEGKKLNDGQKLWIPDDKITNDNLSSRVKDTVEFLNGKWFEWYVYSQIKSELLDRKLKEGEHFGISLKAQKKDSPYFELDIFLINGYQLIGISLTTSSTRELCKLKGFEVIHRVRQIGGDESKAILITGMDKSKTEDLQKDLAYETGSTQKRFVVFGIDDWADIGSKICEEVFK
>NC_010321.1|WP_012269227.1|970250_971783_+|hypothetical-protein
MTLSAVLIDTVSIQEYIFLSNKLKENIGASYIVKKIYEDVLEETLKIAFKGSNVDIKAWEKETKKIKINDPKEKFEIGYIGGGNALILFKDKHEATKFIQNYTKLLLKKTPGLKTAFGIIHDFNLGDFKNSMQRLHESLRENKNKYFPNVTLPKYGFTLDCPRTNESAEHFKDDDEKFISSVAWAKLKFSDKARDEMVVILGDILKDNYTLTNDIEKLGQTEGKDYIAIVHIDGNKMGEKFAKCTNLTEYRNLSISVRNATETAFKKMIEILIEKIENDKIFDSKNEEFKLRKEEDKIILPIRPIILGGDDITFISDGRLGVWLAETFIKEFIKQSINSESLSACGGVSIVKTKYPFYRAYIVAEDLTDRAKQISRKENGSYIDFFISSSGWSGSLEDIFNKHLSTVNGKLHFGPYRIDSINDEKTIENLKNIIKEFKNIPKNKVMKLREILFKVTDKDNGKIFVEELKVKGINLPQIKGMYYHEQIWQNRETPYFDAIELIDFYPEGLL
>NC_010321.1|WP_012269228.1|971779_973963_+|hypothetical-protein
MKIKIDLLSYTLTGSGEGAGIIDSDVVLDDFGFPYIPSRRIKGVLRESAQEVCDILGINDYKIVNSIFGKDGFTEGKLHIGNLYINDYKEIKEEIENLKNDNDSLYKNFVNSLKITSYYTTIRQQTSIEEDNGIAKKGSLRTFRVLKPGLKFEGELYEINPLTKKEKAILYLAVINLKRIGTSRNRGFGEIRCSIEGIEFDNLDKAIQDLKNGIDKTEEIKYSDLKFQGNKSKNIKILPYKITALSPILIAKEIGEQNTIYTEKYIPSTTIRGLFANKFINELGLGKIAHKNNDFYNMFLRGDIIVTPAYPLKNHRIYYPALYLHKEKGKDSNPVYNILEEVPNDIKTKPLNRMIYYIDDKIYTYDISTTFYFHNTRDRVKGHSTGEDIFYYEAINEGEEFKGFIIGDEGYLEGIKNLFKEKFNSFIGRSKSAQYGLVKIEFGDLKDTDMLEIEDKEFIIVAISPIILHNDWGFSEVSEKTLKNYLKKHFNDCDIIVEKIIARTEYVENFVGIWGMKNTRELAYSPGSAFKIIVKGCDNLEEKLNNLLIYGFGEKTDLGFGRVKIYWDLNEEYDMDGEKEKFRHIYPQKSYLIISDIVNREIKEFIKYKGFERAGKFKDQKKISNNLIGRIEGILSETSNFDDWRRKLSKLDKKPAGETLKDTNLWDDLYELDVFNNKSNKIIFDNRLSEVIKDLSLDLDHFELSKTYWVSFLRYLRLFKKTGGEEK
>NC_010321.1|WP_012269229.1|973959_975369_+|hypothetical-protein
MIDNSKLISTIIIKGVLENTSPFVIGTGKGDIIDIEIIKDEIGNPYIPATSFVGALRHHISKNFKEEDKEIWEYFWGSKNRNQENTFDVQSHFMVSDLKIMDNPKEDLITVRDGVAIDEKKGIAKEKAKYDYEIVNKDLEFEFKAEIKIRENFKDKEIEILKILKTILTELEAGKAQFGAFTTKGFGRFNLKNVRILKFDFPKDGVNYLKFLQHEYLPEDKLDLSKIDILPKKDNTDCIINAYFSIKSSLIISSYTTDPDEPDKVHIKYNGKEVLTGTSLKGAIRSRAFKIVNTLCKNNQEENDDLKKLFGWADTENKEKTKYKSRIIIDESKVKNVIEKEQTRIKIDRFTGGTISGALFQSKPLWHNDENVQLKIKIKDAKDWEIGLLLLVLKDLWNEDLPIGGEKNIGRGILKGKNIEIEYKGKKHIIGKSTNDDETNKIVVNDSDKQILEGFVEEFSKKVRDWDVR
>NC_010321.1|WP_012269230.1|975358_975943_+|TIGR03984-family-CRISPR-associated-protein
MLDDIYKIEVTFSKVKARDMDNNDLNYDAFIKEIGEIQNGYVVCWLDYAVLFGIIRNGEIKFYNNESPDFNRYLQKLRIFNENEELYIWRSGNKFKFRYREDLDSNKNGEMVEYIDADQVMYGSKFEIKDEFIEVYEKRGIRYIVPKEFIGNNLIDDINNNKKRLVLHTRNYIGYNEIGQAGFVDSRFLKISII
>NC_010321.1|WP_012269231.1|975961_978136_+|TIGR03986-family-CRISPR-associated-RAMP-protein
MEKAKISIQKTKKGYDYILTFDDGKPLKVHGFNLPQDINGKECEVERINGLPSKIIIDGIEYTKTTTQSNIQENKQTAQQKIKNEPKHNSQIKLFAKAPYNFIPLNECVVKAQDIPEFNKYHKDRYSGYIDLFLTTKTPIYIRRDKEESDFFSIKNGLPIIPGSSLRGMVRNLVEIVSFGKFEFFDKDKRLYYRDVAGKKSNLKDIYSSKISKDRIKAGYLIYDQRKYKIIPSEYDRFQDTSKEFMIEKYNNDYKVWSGRMQKKRKNWIMKSISNSGDFIELTENDIKDYKSDINRNIPEYYDILKMAKDKKVTLPNKIVELPNGVPVFYVEYNDKKGNKKIAFGHTGFFRLPYELTIGDHVPENLKSDDITDFAEAIFGKESKWASRVFFEDAVLDKGQGDIFVEEASPKILASPKPTAFQLYLEQPDGENTKLTDIKHWDNEDTLIRGYKLYWHRNTPDGDSKYSWKASKIEINYDDFIKFLKKANISLDKSVILNSKNIVKDNKKIIINCLYEKLTIEEKKELKEYLLWEKTKAQYTIIKPIKRNIKFKSRIRFENLTKEELGALLFVLDLPENHYHKIGMGKPLGLGSIEIKPSLFIVDRKKRYTSLFNNDTWNLGDEDKTGEINDFKEVFEKYILRNISYNDKGNASSLWETPRLKQLKIMLNWNNTEITDWLKKTRYLMIECPHKDIDYDCICSDSNKDVCNEYRDRPVLPKPEKMIQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_010321_1	1.18\|122820\|38\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	122820-122857	38	CP003186	Thermoanaerobacterium phage THSA-485A, complete genome	27908-27945	1	0.974
NC_010321_1	1.39\|124225\|38\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	124225-124262	38	NC_004979	Thermoanaerobacterium thermosaccharolyticum plasmid pNB2, complete sequence	252-289	1	0.974
NC_010321_8	8.3\|963139\|36\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	963139-963174	36	NZ_KT897276	Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence	11053-11088	6	0.833
NC_010321_8	8.3\|963139\|36\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	963139-963174	36	NZ_KT897280	Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence	10971-11006	6	0.833
NC_010321_8	8.3\|963139\|36\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	963139-963174	36	NZ_KT897275	Clostridium botulinum strain IFR 12/29 plasmid p12/29, complete sequence	11042-11077	6	0.833
NC_010321_8	8.3\|963139\|36\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	963139-963174	36	NZ_KT897277	Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence	11053-11088	6	0.833
NC_010321_8	8.3\|963139\|36\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	963139-963174	36	NZ_KT897278	Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence	10971-11006	6	0.833
NC_010321_8	8.3\|963139\|36\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	963139-963174	36	NZ_KT897279	Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence	10971-11006	6	0.833
NC_010321_6	6.3\|139862\|36\|NC_010321\|CRT,PILER-CR,CRISPRCasFinder	139862-139897	36	NZ_CP015333	Borrelia hermsii HS1 isolate Browne Mountain plasmid lpV47, complete sequence	19023-19058	7	0.806
NC_010321_1	1.7\|122084\|37\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	122084-122120	37	NZ_CP019190	Salmonella enterica subsp. enterica serovar Poona str. ATCC BAA-1673 plasmid pATCCBAA1673_01, complete sequence	128113-128149	8	0.784
NC_010321_1	1.20\|122955\|36\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	122955-122990	36	MN694760	Marine virus AFVG_250M661, complete genome	46244-46279	8	0.778
NC_010321_2	2.8\|126959\|36\|NC_010321\|CRT,PILER-CR,CRISPRCasFinder	126959-126994	36	NZ_CP021437	Bacillus thuringiensis strain C15 plasmid pBMB240, complete sequence	123645-123680	8	0.778
NC_010321_2	2.8\|126959\|36\|NC_010321\|CRT,PILER-CR,CRISPRCasFinder	126959-126994	36	NZ_CP021437	Bacillus thuringiensis strain C15 plasmid pBMB240, complete sequence	33833-33868	8	0.778
NC_010321_2	2.8\|126959\|36\|NC_010321\|CRT,PILER-CR,CRISPRCasFinder	126959-126994	36	NZ_CP015351	Bacillus thuringiensis strain MYBT18246 plasmid p150790, complete sequence	7249-7284	8	0.778
NC_010321_2	2.8\|126959\|36\|NC_010321\|CRT,PILER-CR,CRISPRCasFinder	126959-126994	36	NZ_CP015352	Bacillus thuringiensis strain MYBT18246 plasmid p142098, complete sequence	106305-106340	8	0.778
NC_010321_3	3.35\|133557\|37\|NC_010321\|CRT,PILER-CR,CRISPRCasFinder	133557-133593	37	MN694172	Marine virus AFVG_250M818, complete genome	14504-14540	8	0.784
NC_010321_8	8.18\|964142\|36\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	964142-964177	36	NZ_LR699117	Aquicella lusitana strain SGT-39 plasmid 4	49039-49074	8	0.778
NC_010321_1	1.20\|122955\|36\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	122955-122990	36	NZ_CP011133	Citrobacter amalonaticus Y19 plasmid unnamed, complete sequence	61910-61945	9	0.75
NC_010321_1	1.48\|124827\|36\|NC_010321\|CRISPRCasFinder,CRT	124827-124862	36	NZ_CP031100	Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence	29453-29488	9	0.75
NC_010321_1	1.48\|124827\|36\|NC_010321\|CRISPRCasFinder,CRT	124827-124862	36	NZ_CP014147	Clostridium botulinum strain CDC_67190 plasmid pNPD12_2, complete sequence	6019-6054	9	0.75
NC_010321_3	3.25\|132885\|35\|NC_010321\|CRT,PILER-CR,CRISPRCasFinder	132885-132919	35	MN334766	Serratia phage PCH45, complete genome	117345-117379	10	0.714
NC_010321_1	1.36\|124025\|36\|NC_010321\|PILER-CR,CRISPRCasFinder,CRT	124025-124060	36	NC_019924	Clostridium phage phi8074-B1, complete genome	44692-44727	11	0.694
NC_010321_5	5.7\|137604\|38\|NC_010321\|CRT,PILER-CR,CRISPRCasFinder	137604-137641	38	NC_010507	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD08, complete sequence	1319-1356	11	0.711

1. spacer 1.18|122820|38|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to CP003186 (Thermoanaerobacterium phage THSA-485A, complete genome) position: , mismatch: 1, identity: 0.974

tgcaaaatttcagaaaatttcaggaaaggaggtatgcg	CRISPR spacer
tgcaaaatttcagaaaatttcaggaaaggaggtatgct	Protospacer
*************************************

2. spacer 1.39|124225|38|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NC_004979 (Thermoanaerobacterium thermosaccharolyticum plasmid pNB2, complete sequence) position: , mismatch: 1, identity: 0.974

ccaccttttttacctcaattagttctatagtattaaag	CRISPR spacer
ccaccttttttacctcaattagttctatagtattaaaa	Protospacer
*************************************.

3. spacer 8.3|963139|36|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897276 (Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence) position: , mismatch: 6, identity: 0.833

-tttgacgttgtttcttgctccacttcttctttttgc	CRISPR spacer
atttcatgat-tttgtttctccacttcttctttttgc	Protospacer
 *** *.* * *** ** *******************

4. spacer 8.3|963139|36|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897280 (Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence) position: , mismatch: 6, identity: 0.833

-tttgacgttgtttcttgctccacttcttctttttgc	CRISPR spacer
atttcatgat-tttgtttctccacttcttctttttgc	Protospacer
 *** *.* * *** ** *******************

5. spacer 8.3|963139|36|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897275 (Clostridium botulinum strain IFR 12/29 plasmid p12/29, complete sequence) position: , mismatch: 6, identity: 0.833

-tttgacgttgtttcttgctccacttcttctttttgc	CRISPR spacer
atttcatgat-tttgtttctccacttcttctttttgc	Protospacer
 *** *.* * *** ** *******************

6. spacer 8.3|963139|36|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897277 (Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence) position: , mismatch: 6, identity: 0.833

-tttgacgttgtttcttgctccacttcttctttttgc	CRISPR spacer
atttcatgat-tttgtttctccacttcttctttttgc	Protospacer
 *** *.* * *** ** *******************

7. spacer 8.3|963139|36|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897278 (Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence) position: , mismatch: 6, identity: 0.833

-tttgacgttgtttcttgctccacttcttctttttgc	CRISPR spacer
atttcatgat-tttgtttctccacttcttctttttgc	Protospacer
 *** *.* * *** ** *******************

8. spacer 8.3|963139|36|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KT897279 (Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence) position: , mismatch: 6, identity: 0.833

-tttgacgttgtttcttgctccacttcttctttttgc	CRISPR spacer
atttcatgat-tttgtttctccacttcttctttttgc	Protospacer
 *** *.* * *** ** *******************

9. spacer 6.3|139862|36|NC_010321|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP015333 (Borrelia hermsii HS1 isolate Browne Mountain plasmid lpV47, complete sequence) position: , mismatch: 7, identity: 0.806

gctggtgct--tattattggaaaggatataaacaagca	CRISPR spacer
--ttattcttgtattattgcaaaggatataaataagca	Protospacer
  * .* **  ******** ************.*****

10. spacer 1.7|122084|37|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019190 (Salmonella enterica subsp. enterica serovar Poona str. ATCC BAA-1673 plasmid pATCCBAA1673_01, complete sequence) position: , mismatch: 8, identity: 0.784

tgcatttccccaccttcgcggtaaagctccacgaacg	CRISPR spacer
tacctctccccaccttcgcgataaagatccacatccg	Protospacer
*.* *.**************.***** *****.  **

11. spacer 1.20|122955|36|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to MN694760 (Marine virus AFVG_250M661, complete genome) position: , mismatch: 8, identity: 0.778

agatactttttaacttctttatatatttaataaaaa	CRISPR spacer
aaaaactttttaaattctttatatattaaaaagtta	Protospacer
*.* ********* ************* ** *.  *

12. spacer 2.8|126959|36|NC_010321|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021437 (Bacillus thuringiensis strain C15 plasmid pBMB240, complete sequence) position: , mismatch: 8, identity: 0.778

agctgttgt------tttgacatattcatcatcctttctgaa	CRISPR spacer
------tgtaaagcgtttgacatatttgtcatcctttctgaa	Protospacer
      ***      ***********..**************

13. spacer 2.8|126959|36|NC_010321|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP021437 (Bacillus thuringiensis strain C15 plasmid pBMB240, complete sequence) position: , mismatch: 8, identity: 0.778

agctgttgt------tttgacatattcatcatcctttctgaa	CRISPR spacer
------tgtaaagcgtttgacatatttgtcatcctttctgaa	Protospacer
      ***      ***********..**************

14. spacer 2.8|126959|36|NC_010321|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP015351 (Bacillus thuringiensis strain MYBT18246 plasmid p150790, complete sequence) position: , mismatch: 8, identity: 0.778

agctgttgt------tttgacatattcatcatcctttctgaa	CRISPR spacer
------tgtaaagcgtttgacatatttgtcatcctttctgaa	Protospacer
      ***      ***********..**************

15. spacer 2.8|126959|36|NC_010321|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP015352 (Bacillus thuringiensis strain MYBT18246 plasmid p142098, complete sequence) position: , mismatch: 8, identity: 0.778

agctgttgt------tttgacatattcatcatcctttctgaa	CRISPR spacer
------tgtaaagcgtttgacatatttgtcatcctttctgaa	Protospacer
      ***      ***********..**************

16. spacer 3.35|133557|37|NC_010321|CRT,PILER-CR,CRISPRCasFinder matches to MN694172 (Marine virus AFVG_250M818, complete genome) position: , mismatch: 8, identity: 0.784

tttttaagattttctgttttatcttttatcttgtcta	CRISPR spacer
tttttaagattttctaatttatcttttaaatctttca	Protospacer
***************. ***********  *. *..*

17. spacer 8.18|964142|36|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR699117 (Aquicella lusitana strain SGT-39 plasmid 4) position: , mismatch: 8, identity: 0.778

aattattgcagaggcaatggcaaaaggcttaagcaa---	CRISPR spacer
aattattgcagatgcaatggccaaag---tgggtaaaga	Protospacer
************ ******** ****   *..*.**

18. spacer 1.20|122955|36|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP011133 (Citrobacter amalonaticus Y19 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.75

agatactttttaacttctttatatatttaataaaaa	CRISPR spacer
ttcttctttttaactttttaatatatttaatttaat	Protospacer
   * ***********.** ***********  **

19. spacer 1.48|124827|36|NC_010321|CRISPRCasFinder,CRT matches to NZ_CP031100 (Clostridium botulinum strain CFSAN034202 plasmid p1_CFSAN034202, complete sequence) position: , mismatch: 9, identity: 0.75

agtattaaaaattaaggaggtttaaaaaatggaaaa	CRISPR spacer
tttattaaaaatttaggaggtataaaaatgaataaa	Protospacer
  *********** ******* ******  .. ***

20. spacer 1.48|124827|36|NC_010321|CRISPRCasFinder,CRT matches to NZ_CP014147 (Clostridium botulinum strain CDC_67190 plasmid pNPD12_2, complete sequence) position: , mismatch: 9, identity: 0.75

agtattaaaaattaaggaggtttaaaaaatggaaaa	CRISPR spacer
tttattaaaaatttaggaggtataaaaatgaataaa	Protospacer
  *********** ******* ******  .. ***

21. spacer 3.25|132885|35|NC_010321|CRT,PILER-CR,CRISPRCasFinder matches to MN334766 (Serratia phage PCH45, complete genome) position: , mismatch: 10, identity: 0.714

ttttatttcctcctccttaatttttttattttccc	CRISPR spacer
ctcggttccctcctcctttatttttttatttgttg	Protospacer
.*. .**.********** ************ ..

22. spacer 1.36|124025|36|NC_010321|PILER-CR,CRISPRCasFinder,CRT matches to NC_019924 (Clostridium phage phi8074-B1, complete genome) position: , mismatch: 11, identity: 0.694

agtactaaagattgaggaggtataaacatggaagag	CRISPR spacer
aacactaaagttttaggaggtataaacatatggata	Protospacer
*..******* ** ***************. ... .

23. spacer 5.7|137604|38|NC_010321|CRT,PILER-CR,CRISPRCasFinder matches to NC_010507 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD08, complete sequence) position: , mismatch: 11, identity: 0.711

aaatactcgccggcgcgaaccttaatcttcaccggcca	CRISPR spacer
tcatactcgccggcgcggaccttgatcttcgagaggtc	Protospacer
  ***************.*****.******.  .* .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

86984 : 130990

Wolbachia_phage(17.65%)

integrase,transposase,tRNA,protease

attL 80557:80602|attR 88352:88397

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
80557:80602	attL	NA	NA	NA	NA
WP_012268865.1\|86984_88196_+\|integrase	tyrosine-type recombinase/integrase	A0A2R2ZGM9	Clostridioides_phage	4.2e-43	32.3
WP_039913173.1\|88820_89048_+	DUF3006 domain-containing protein	Q0H256	Geobacillus_phage	3.9e-11	48.4
88352:88397	attR	NA	NA	NA	NA
WP_003867862.1\|89098_90055_+	MBL fold metallo-hydrolase	Q332C0	Clostridium_botulinum_C_phage	2.0e-72	54.5
WP_012268866.1\|90141_91389_+	DUF1015 domain-containing protein	NA	NA	NA	NA
WP_012268867.1\|91841_93254_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.0e-32	28.3
WP_009052096.1\|93410_94853_+	M1 family metallopeptidase	NA	NA	NA	NA
WP_012268868.1\|94849_95833_-	ATP-binding protein	H7BWC4	unidentified_phage	1.9e-14	37.9
WP_003867867.1\|95825_96800_-	DnaD domain protein	NA	NA	NA	NA
WP_009052097.1\|97037_98396_+	peptidoglycan DD-metalloendopeptidase family protein	A0A7K9	Microcystis_virus	4.4e-25	54.5
WP_003867869.1\|98573_99380_+	hypothetical protein	NA	NA	NA	NA
WP_012268869.1\|99525_100779_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_012268870.1\|100844_101948_+\|protease	trypsin-like serine protease	W5SAB9	Pithovirus	2.3e-11	30.0
WP_003870754.1\|101958_102126_+	CxxH/CxxC protein	NA	NA	NA	NA
WP_012268871.1\|102143_102611_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_009052100.1\|102601_103003_-	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_012268872.1\|103134_104355_+\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	4.3e-64	35.2
WP_012268875.1\|104860_105679_+	hypothetical protein	NA	NA	NA	NA
WP_012268876.1\|105650_106649_+	deoxyribodipyrimidine photo-lyase	NA	NA	NA	NA
WP_009052441.1\|106847_108107_-\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	9.4e-54	37.2
WP_003867878.1\|108753_109338_+	glutaredoxin	NA	NA	NA	NA
WP_003868733.1\|109431_109716_+	co-chaperone GroES	A0A221S4G8	uncultured_virus	4.6e-09	37.3
WP_012268877.1\|109903_110650_+	Fe-S cluster assembly ATPase SufC	A0A285PWH2	Cedratvirus	4.6e-08	26.3
WP_012268878.1\|110669_112073_+	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_012268879.1\|112083_113133_+	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_012268880.1\|113129_114359_+	cysteine desulfurase	Q2XUY6	environmental_halophage	2.6e-109	45.8
WP_003868738.1\|114355_114769_+	SUF system NifU family Fe-S cluster assembly protein	A0A2P1CJL8	Mycobacterium_phage	4.6e-10	32.3
WP_004399630.1\|114957_115713_+	CRISPR-associated endoribonuclease Cas6	NA	NA	NA	NA
WP_012268881.1\|115732_117496_+	TIGR02556 family CRISPR-associated protein	NA	NA	NA	NA
WP_012268882.1\|117496_118408_+	type I-B CRISPR-associated protein Cas7/Csh2	NA	NA	NA	NA
WP_003871404.1\|118420_119134_+	type I-B CRISPR-associated protein Cas5	NA	NA	NA	NA
WP_012268883.1\|119117_121472_+	CRISPR-associated helicase/endonuclease Cas3	A0A2R2ZGW0	Clostridioides_phage	4.7e-06	22.1
WP_003869923.1\|124977_126198_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.5e-56	33.7
WP_003869923.1\|128110_129331_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.5e-56	33.7
WP_003869923.1\|129769_130990_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.5e-56	33.7

DBSCAN-SWA_2

135695 : 195524

Wolbachia_phage(19.05%)

transposase,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003869923.1\|135695_136916_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.5e-56	33.7
WP_003869923.1\|138221_139442_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.5e-56	33.7
WP_012268884.1\|141548_142769_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.5e-56	34.0
WP_009052111.1\|142907_143636_+	peptidase E	NA	NA	NA	NA
WP_003867574.1\|143964_144462_+	CRISPR-associated protein Cas4	NA	NA	NA	NA
WP_004399636.1\|144458_145451_+	type I-B CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_003871087.1\|145467_145731_+	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_012268885.1\|145851_147777_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_003871085.1\|148037_148817_+	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	6.6e-42	40.2
WP_012268886.1\|149271_150684_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.0e-32	28.3
WP_003867580.1\|150923_151364_+	ACT domain-containing protein	NA	NA	NA	NA
WP_012268887.1\|151376_152633_+	homoserine dehydrogenase	NA	NA	NA	NA
WP_009052114.1\|152636_153692_+	threonine synthase	NA	NA	NA	NA
WP_012268888.1\|153681_154608_+	homoserine kinase	NA	NA	NA	NA
WP_012268889.1\|155057_160388_+	S8 family serine peptidase	A0A217EQY2	Bacillus_phage	2.0e-12	31.1
WP_012268890.1\|160591_161674_+	alanine--glyoxylate aminotransferase family protein	NA	NA	NA	NA
WP_012268891.1\|161687_163283_+	phosphoglycerate dehydrogenase	A0A1V0SBV6	Catovirus	3.2e-43	32.8
WP_012268892.1\|163331_164150_-	histidinol-phosphatase	NA	NA	NA	NA
WP_012268893.1\|164509_166111_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	4.9e-156	52.5
WP_011025138.1\|166372_167416_+\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	7.2e-60	40.2
WP_012268867.1\|168065_169478_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.0e-32	28.3
WP_013570768.1\|169639_170470_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	2.8e-22	32.9
WP_012268895.1\|170435_171368_+	1-phosphofructokinase	NA	NA	NA	NA
WP_012268896.1\|171373_171820_+	PTS transporter subunit EIIA	NA	NA	NA	NA
WP_012268897.1\|171843_173202_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_012268898.1\|173230_173542_-	hypothetical protein	NA	NA	NA	NA
WP_004399058.1\|173543_173981_-	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	5.4e-17	35.7
WP_012268899.1\|174144_175053_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_004399054.1\|175165_176179_+	LacI family DNA-binding transcriptional regulator	C6ZCU4	Enterobacteria_phage	2.3e-26	29.8
WP_012268900.1\|176192_177587_-	UDP-N-acetylmuramate--L-alanine ligase	NA	NA	NA	NA
WP_012268901.1\|177761_178586_+	pur operon repressor	NA	NA	NA	NA
WP_004399029.1\|178728_179007_+	septation regulator SpoVG	NA	NA	NA	NA
WP_004399028.1\|179112_180486_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L277	Tupanvirus	3.1e-34	38.8
WP_012268902.1\|180491_181442_+	ribose-phosphate diphosphokinase	A0A2K9L8D8	Tupanvirus	2.3e-44	39.3
WP_012268903.1\|181886_183299_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.2e-33	28.1
WP_003867604.1\|183438_184122_+	response regulator transcription factor	W8CYM9	Bacillus_phage	4.4e-50	44.8
WP_003867605.1\|184124_185537_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	3.5e-49	37.7
WP_012268904.1\|185801_187163_+	PDZ domain-containing protein	A0A1B1IRH0	uncultured_Mediterranean_phage	1.4e-15	33.3
WP_012268905.1\|187291_187846_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_012268906.1\|187877_188246_+	hypothetical protein	NA	NA	NA	NA
WP_012268907.1\|188251_191749_+	transcription-repair coupling factor	NA	NA	NA	NA
WP_009052126.1\|191814_192720_+	foldase	NA	NA	NA	NA
WP_003867613.1\|192825_193377_+	stage V sporulation protein T	A0A2I7SC16	Paenibacillus_phage	4.3e-11	51.9
WP_012268908.1\|193449_194304_+	sporulation peptidase YabG	NA	NA	NA	NA
WP_011025138.1\|194480_195524_+\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	7.2e-60	40.2

DBSCAN-SWA_3

308502 : 316439

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012268958.1\|308502_309198_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.9e-41	40.1
WP_012268959.1\|309190_310546_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.0e-37	35.6
WP_009053008.1\|310620_310869_+	SHOCT domain-containing protein	NA	NA	NA	NA
WP_081448161.1\|311100_311196_-	DUF1540 domain-containing protein	NA	NA	NA	NA
WP_009053006.1\|311613_311979_+	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	2.3e-13	36.2
WP_012268960.1\|311999_314099_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	2.5e-112	36.3
WP_009053004.1\|314269_315208_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	1.7e-100	64.3
WP_009053003.1\|315284_316439_+	cysteine desulfurase NifS	H7BUW1	unidentified_phage	1.9e-45	42.9

DBSCAN-SWA_4

436461 : 484793

Bacillus_phage(25.0%)

coat,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003868592.1\|436461_437196_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_003868593.1\|437284_437716_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_003868594.1\|437730_438123_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_012268996.1\|444669_445956_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_013570779.1\|446055_446307_+	hypothetical protein	NA	NA	NA	NA
WP_012268997.1\|446272_447259_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	2.0e-19	32.3
WP_012268998.1\|447255_448050_+	ABC transporter permease	NA	NA	NA	NA
WP_012268999.1\|448054_448816_+	hypothetical protein	NA	NA	NA	NA
WP_012269003.1\|453159_453453_+	hypothetical protein	NA	NA	NA	NA
WP_012268840.1\|454528_455329_-	AAA family ATPase	NA	NA	NA	NA
WP_012269005.1\|455345_456671_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_013570782.1\|456807_457389_-	hypothetical protein	NA	NA	NA	NA
WP_156770929.1\|458185_459016_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	2.0e-76	59.3
WP_012269009.1\|458979_459255_-\|transposase	IS3 family transposase	A0A1P8CWP5	Bacillus_phage	3.6e-19	58.1
WP_003868477.1\|460019_460514_+	ferritin	NA	NA	NA	NA
WP_003868478.1\|460535_460910_+	iron-binding protein	NA	NA	NA	NA
WP_003868479.1\|461616_462129_+	hypothetical protein	NA	NA	NA	NA
WP_012269010.1\|462147_463788_+	carbon starvation protein A	NA	NA	NA	NA
WP_012269011.1\|464138_465503_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_003868482.1\|465905_466406_+	Na+/H+ antiporter subunit E	NA	NA	NA	NA
WP_003868483.1\|466386_466662_+	pH regulation protein F	NA	NA	NA	NA
WP_003868484.1\|466663_466981_+	monovalent cation/H(+) antiporter subunit G	NA	NA	NA	NA
WP_003868485.1\|466982_467234_+	DUF4040 domain-containing protein	NA	NA	NA	NA
WP_009052829.1\|467235_467961_+	sodium:proton antiporter	NA	NA	NA	NA
WP_009052828.1\|467957_468323_+	cation:proton antiporter subunit C	NA	NA	NA	NA
WP_012268645.1\|468331_469792_+	NADH dehydrogenase	NA	NA	NA	NA
WP_012269013.1\|469806_471486_+	NADH dehydrogenase	NA	NA	NA	NA
WP_009052825.1\|471515_472178_+	hypothetical protein	NA	NA	NA	NA
WP_009052824.1\|472336_473857_+	FAD-dependent thymidylate synthase	B6EFA9	Stygiolobus_rod-shaped_virus	4.4e-05	27.8
WP_003868493.1\|473874_474189_+	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_003868494.1\|474267_474450_+	hypothetical protein	NA	NA	NA	NA
WP_003868495.1\|474465_474741_+\|coat	spore coat protein	NA	NA	NA	NA
WP_009052823.1\|474830_475745_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	1.4e-70	44.4
WP_009052822.1\|475773_476757_-	LysM peptidoglycan-binding domain-containing protein	A0A286N2U4	Arthrobacter_phage	8.7e-07	28.0
WP_003868498.1\|476862_477543_+	N-acetylmuramoyl-L-alanine amidase CwlD	A0A067ZJB6	Vibrio_phage	1.9e-16	32.2
WP_003868499.1\|477626_478259_+	pyrophosphatase PpaX	NA	NA	NA	NA
WP_003868501.1\|478723_480160_+\|transposase	IS200/IS605 family element transposase accessory protein TnpB	NA	NA	NA	NA
WP_012269014.1\|480305_481250_+	MoxR family ATPase	NA	NA	NA	NA
WP_003868505.1\|482234_482648_+	universal stress protein	NA	NA	NA	NA
WP_012269017.1\|482657_483053_-	BON domain-containing protein	NA	NA	NA	NA
WP_009052441.1\|483533_484793_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	9.4e-54	37.2

DBSCAN-SWA_5

873302 : 881590

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003871580.1\|873302_874028_+	RNA polymerase sporulation sigma factor SigE	A0A2H4JC68	uncultured_Caudovirales_phage	1.7e-20	45.7
WP_004402381.1\|874097_874868_+	RNA polymerase sporulation sigma factor SigG	A0A0Y0AU18	Bacillus_phage	6.3e-45	44.1
WP_003867938.1\|874936_875182_+	YlmC/YmxH family sporulation protein	NA	NA	NA	NA
WP_003867939.1\|875249_875726_+	transcriptional repressor NrdR	NA	NA	NA	NA
WP_003867940.1\|875778_876483_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.5e-40	39.3
WP_012269190.1\|876482_877853_+	PAS domain S-box protein	W8CYF6	Bacillus_phage	2.0e-41	40.2
WP_012269191.1\|877934_878819_+	phosphate ABC transporter substrate-binding protein	E3SM63	Prochlorococcus_phage	2.8e-12	26.8
WP_003867943.1\|879015_879915_+	phosphate ABC transporter permease subunit PstC	NA	NA	NA	NA
WP_003867944.1\|879911_880799_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_012269192.1\|880840_881590_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.4e-18	31.9

DBSCAN-SWA_6

1374998 : 1429535

Pseudomonas_phage(13.33%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012269396.1\|1374998_1375706_-\|tRNA	tRNA 2-thiocytidine biosynthesis protein TtcA	NA	NA	NA	NA
WP_009052448.1\|1375816_1376992_+	class I SAM-dependent rRNA methyltransferase	NA	NA	NA	NA
WP_003868407.1\|1377058_1377292_+	peptidoglycan-binding protein	A0A2D1GR13	Pseudomonas_phage	1.1e-08	51.7
WP_012268739.1\|1377288_1377861_-	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_012269397.1\|1377874_1378783_-	dihydroorotate dehydrogenase	NA	NA	NA	NA
WP_012269398.1\|1378779_1379508_-	dihydroorotate dehydrogenase electron transfer subunit	NA	NA	NA	NA
WP_012269399.1\|1379516_1380440_-	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_003868402.1\|1380497_1381793_-	dihydroorotase	NA	NA	NA	NA
WP_003868401.1\|1381794_1382709_-	aspartate carbamoyltransferase catalytic subunit	A7RB08	Paramecium_bursaria_Chlorella_virus	4.9e-36	37.8
WP_003868400.1\|1382914_1383451_-	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_012269401.1\|1383667_1384663_+	AIR synthase	NA	NA	NA	NA
WP_012269402.1\|1384753_1385671_-	RluA family pseudouridine synthase	NA	NA	NA	NA
WP_012269403.1\|1385675_1386110_-	signal peptidase II	NA	NA	NA	NA
WP_012269404.1\|1386477_1387443_-	DUF4236 domain-containing protein	NA	NA	NA	NA
WP_003867561.1\|1389593_1390949_-\|transposase	IS1380-like element ISTps2 family transposase	NA	NA	NA	NA
WP_012269405.1\|1392918_1393389_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	7.1e-39	57.6
WP_013570817.1\|1393498_1395661_-	ribonuclease R	Q0GXV6	Lactococcus_phage	7.4e-83	39.4
WP_003867907.1\|1395670_1396222_-	HDIG domain-containing protein	NA	NA	NA	NA
WP_003867908.1\|1396347_1398981_-	pyruvate, phosphate dikinase	H8YJB7	Vibrio_phage	7.4e-93	41.0
WP_003867909.1\|1398977_1399790_-	kinase/pyrophosphorylase	NA	NA	NA	NA
WP_003867910.1\|1399803_1400445_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003867911.1\|1400636_1402025_-\|tRNA	glycine--tRNA ligase	A0A1V0SAN4	Catovirus	3.0e-53	27.9
WP_003867912.1\|1402134_1402545_-	DUF4342 domain-containing protein	NA	NA	NA	NA
WP_003867913.1\|1402559_1403306_-	DNA repair protein RecO	NA	NA	NA	NA
WP_003867914.1\|1403312_1403984_-	deoxyribose-phosphate aldolase	NA	NA	NA	NA
WP_003867915.1\|1404019_1404928_-	GTPase Era	NA	NA	NA	NA
WP_003867916.1\|1404939_1405638_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_003867917.1\|1405642_1406122_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_012269407.1\|1406118_1408185_-	HDIG domain-containing protein	NA	NA	NA	NA
WP_003869507.1\|1408188_1409184_-	PhoH family protein	A0A0S0MVD6	Pseudomonas_phage	2.1e-48	41.9
WP_009052245.1\|1409180_1410368_-	sporulation protein YqfD	NA	NA	NA	NA
WP_003867921.1\|1410379_1410649_-	sporulation protein YqfC	NA	NA	NA	NA
WP_012269408.1\|1410744_1411794_+	asparaginase	NA	NA	NA	NA
WP_003867923.1\|1411819_1412263_-	GatB/YqeY domain-containing protein	G3MAQ0	Bacillus_virus	1.1e-06	33.1
WP_003867924.1\|1412277_1412463_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_003867925.1\|1412574_1412919_-	histidine triad nucleotide-binding protein	NA	NA	NA	NA
WP_003867926.1\|1412955_1414323_-\|tRNA	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))- methylthiotransferase MtaB	NA	NA	NA	NA
WP_012269410.1\|1414906_1415815_-	GGDEF domain-containing protein	G3MA91	Bacillus_virus	7.5e-21	32.4
WP_012269411.1\|1415990_1417373_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	5.3e-10	74.5
WP_012269412.1\|1417805_1418402_-	HD domain-containing protein	NA	NA	NA	NA
WP_083758533.1\|1418677_1418845_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	3.7e-11	63.8
WP_081448155.1\|1418896_1419139_-\|transposase	transposase	NA	NA	NA	NA
WP_003868803.1\|1419640_1419802_-	hypothetical protein	NA	NA	NA	NA
WP_012269414.1\|1419911_1420613_-	hypothetical protein	NA	NA	NA	NA
WP_012269415.1\|1420636_1421431_-	radical SAM protein	A0A1L7N0Q5	Ralstonia_phage	1.0e-05	24.3
WP_012269416.1\|1421427_1423140_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	6.0e-19	19.6
WP_012269417.1\|1423153_1424587_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	2.4e-45	31.4
WP_012269418.1\|1425013_1425940_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	3.1e-46	39.3
WP_012269419.1\|1426014_1426947_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_013570820.1\|1426978_1427248_-	hypothetical protein	NA	NA	NA	NA
WP_012269421.1\|1427223_1427463_-	hypothetical protein	NA	NA	NA	NA
WP_041589953.1\|1427555_1427975_-	YeeE/YedE family protein	NA	NA	NA	NA
WP_012269422.1\|1428125_1429535_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_7

1748214 : 1756992

Synechococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003866805.1\|1748214_1748829_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.3e-20	35.9
WP_003866806.1\|1748825_1749836_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.9e-74	45.5
WP_012269566.1\|1749853_1751251_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.0e-60	34.4
WP_012269567.1\|1751229_1753431_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	6.9e-169	43.9
WP_003866809.1\|1753433_1754108_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_003866810.1\|1754110_1754359_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_003866811.1\|1754360_1755068_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	NA	NA	NA	NA
WP_003866812.1\|1755087_1755549_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.7e-24	45.6
WP_003866813.1\|1755609_1756992_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	6.9e-58	33.9

DBSCAN-SWA_8

2079923 : 2114923

Staphylococcus_phage(25.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003867100.1\|2079923_2080394_-\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_009051921.1\|2080775_2081207_+	nickel-responsive transcriptional regulator NikR	NA	NA	NA	NA
WP_012269717.1\|2081220_2081913_+	cobalt transporter CbiM	NA	NA	NA	NA
WP_003867103.1\|2081909_2082227_+	hypothetical protein	NA	NA	NA	NA
WP_012269718.1\|2082219_2083035_+	cobalt ECF transporter T component CbiQ	NA	NA	NA	NA
WP_012269719.1\|2083046_2083775_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.5e-14	30.2
WP_012269720.1\|2083869_2085840_-	ferrous iron transport protein B	NA	NA	NA	NA
WP_012269721.1\|2085836_2086100_-	ferrous iron transport protein A	NA	NA	NA	NA
WP_003867108.1\|2086309_2086798_+	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_012269722.1\|2086794_2087961_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_012269723.1\|2088378_2089527_-	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
WP_012269725.1\|2090385_2090961_+	Uma2 family endonuclease	NA	NA	NA	NA
WP_012268955.1\|2091096_2092314_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	6.9e-46	46.8
WP_012269726.1\|2092628_2094041_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	7.1e-34	28.1
WP_012268840.1\|2094395_2095196_-	AAA family ATPase	NA	NA	NA	NA
WP_012268839.1\|2095212_2096538_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_013570760.1\|2096674_2097256_-	hypothetical protein	NA	NA	NA	NA
WP_012269727.1\|2097693_2099106_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	4.9e-35	28.2
WP_009051944.1\|2099608_2100532_-	ribose ABC transporter substrate-binding protein RbsB	C6ZCU4	Enterobacteria_phage	8.2e-07	26.9
WP_004399903.1\|2100614_2101571_-	ribose ABC transporter permease	NA	NA	NA	NA
WP_012269728.1\|2101572_2103063_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.7e-20	33.2
WP_009051946.1\|2103086_2103479_-	D-ribose pyranase	NA	NA	NA	NA
WP_009051947.1\|2103475_2104405_-	ribokinase	NA	NA	NA	NA
WP_012269729.1\|2104420_2105425_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_011025138.1\|2105639_2106683_+\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	7.2e-60	40.2
WP_012269267.1\|2107515_2108799_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_012268840.1\|2109926_2110727_-	AAA family ATPase	NA	NA	NA	NA
WP_012269005.1\|2110743_2112069_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_013570841.1\|2112205_2112787_-	hypothetical protein	NA	NA	NA	NA
WP_013570853.1\|2113726_2114923_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	G3MB42	Bacillus_virus	4.8e-116	53.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_010321

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection