CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_009900	Rickettsia massiliae MTU5, complete sequence	1 crisprs	PD-DExK,cas3,DEDDh	0	0	2	0
NC_009897	Rickettsia massiliae MTU5 plasmid pRMA, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_009900_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009900_1

502793-502892

Orphan

Consensus_repeat	Method
TTTAAAATTCCTTTTGAAGAACTAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_009900_1

>merge|NC_009900|1|502793-502892|CRISPRCasFinder
TTTAAAATTCCTTTTGAAGAACTAATGGAACAAAAGGAATTACAGAAAAAATTATATCAAGAATTATTACCTGATTTCAAAATTCCTTTTGAAGAACTAA

>NC_009900|1|1|502793-502892|CRISPRCasFinder
TTTAAAATTCCTTTTGAAGAACTAA	TGGAACAAAAGGAATTACAGAAAAAATTATATCAAGAATTATTACCTGAT
TTCAAAATTCCTTTTGAAGAACTAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_009900.1\|WP_041404974.1\|516181_518485_+\|NADP-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|235976
NC_009900.1\|WP_041404628.1\|512454_512667_-\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786
NC_009900.1\|WP_012152687.1\|495934_496663_-\|NADH-quinone-oxidoreductase-subunit-C	unknown	unknown	gnl\|CDD\|235691
NC_009900.1\|WP_012152692.1\|501217_502138_+\|site-specific-tyrosine-recombinase-XerD	unknown	unknown	gnl\|CDD\|234713
NC_009900.1\|WP_012152700.1\|515110_516043_+\|AEC-family-transporter	unknown	unknown	gnl\|CDD\|223751
NC_009900.1\|WP_012152688.1\|496640_497165_-\|NADH-quinone-oxidoreductase-subunit-B	unknown	unknown	gnl\|CDD\|235797
NC_009900.1\|WP_041404625.1\|505565_507083_+\|apolipoprotein-N-acyltransferase	unknown	unknown	gnl\|CDD\|234721
NC_009900.1\|WP_012152690.1\|497699_498938_-\|O-antigen-ligase-family-protein	unknown	unknown	gnl\|CDD\|225844
NC_009900.1\|WP_041404621.1\|498938_499412_-\|DUF2155-domain-containing-protein	unknown	unknown	gnl\|CDD\|227106
NC_009900.1\|WP_041404624.1\|504518_504713_+\|palindromic-element-RPE4-domain-containing-protein	unknown	unknown	gnl\|CDD\|274777
NC_009900.1\|WP_012152684.1\|493496_493745_-\|membrane-protein-insertion-efficiency-factor-YidD	unknown	unknown	gnl\|CDD\|172864
NC_009900.1\|WP_081427919.1\|512713_513232_-\|disulfide-bond-formation-protein-B	unknown	unknown	gnl\|CDD\|224412
NC_009900.1\|WP_012152699.1\|513412_514981_+\|lysine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234829
NC_009900.1\|WP_041404627.1\|507773_508577_+\|N-acetylmuramoyl-L-alanine-amidase	unknown	unknown	gnl\|CDD\|225567
NC_009900.1\|WP_012152685.1\|493737_494241_-\|NADH-quinone-oxidoreductase-subunit-NuoE	unknown	unknown	gnl\|CDD\|181024
NC_009900.1\|WP_012152695.1\|504707_505490_-\|enoyl-ACP-reductase-FabI	unknown	unknown	gnl\|CDD\|168626
NC_009900.1\|WP_014365940.1\|497169_497541_-\|NADH-quinone-oxidoreductase-subunit-A	unknown	unknown	gnl\|CDD\|180638
NC_009900.1\|WP_041404971.1\|494660_495836_-\|NADH-dehydrogenase-(quinone)-subunit-D	unknown	unknown	gnl\|CDD\|180385
NC_009900.1\|WP_041404620.1\|492661_493207_-\|DNA-3-methyladenine-glycosylase	unknown	unknown	gnl\|CDD\|234840
NC_009900.1\|WP_041404623.1\|503355_504519_+\|DUF5410-domain-containing-protein	unknown	unknown	gnl\|CDD\|375184

Protein	Function_ID	Function_description	E-value
NC_009900.1\|WP_041404974.1\|516181_518485_+\|NADP-dependent-malic-enzyme	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NC_009900.1\|WP_041404628.1\|512454_512667_-\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	2.90622e-11
NC_009900.1\|WP_012152687.1\|495934_496663_-\|NADH-quinone-oxidoreductase-subunit-C	gnl\|CDD\|235691	PRK06074, PRK06074, NADH dehydrogenase subunit C; Provisional.	1.40215e-88
NC_009900.1\|WP_012152692.1\|501217_502138_+\|site-specific-tyrosine-recombinase-XerD	gnl\|CDD\|234713	PRK00283, xerD, tyrosine recombinase.	1.36549e-153
NC_009900.1\|WP_012152700.1\|515110_516043_+\|AEC-family-transporter	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	5.94856e-59
NC_009900.1\|WP_012152688.1\|496640_497165_-\|NADH-quinone-oxidoreductase-subunit-B	gnl\|CDD\|235797	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB.	5.55608e-112
NC_009900.1\|WP_041404625.1\|505565_507083_+\|apolipoprotein-N-acyltransferase	gnl\|CDD\|234721	PRK00302, lnt, apolipoprotein N-acyltransferase; Reviewed.	5.19324e-174
NC_009900.1\|WP_012152690.1\|497699_498938_-\|O-antigen-ligase-family-protein	gnl\|CDD\|225844	COG3307, RfaL, Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane].	2.08428e-43
NC_009900.1\|WP_041404621.1\|498938_499412_-\|DUF2155-domain-containing-protein	gnl\|CDD\|227106	COG4765, COG4765, Uncharacterized protein conserved in bacteria [Function unknown].	5.03341e-74
NC_009900.1\|WP_041404624.1\|504518_504713_+\|palindromic-element-RPE4-domain-containing-protein	gnl\|CDD\|274777	TIGR03777, RPE4, Rickettsial palindromic element RPE4 domain. This model describes protein translations of a family, RPE4, of Rickettsia palindromic elements (RPE). The elements spread within a genome as selfish genetic elements, inserting into genes additional coding region that does not disrupt the reading frame. This model finds RPE-encoded regions in several Rickettsial species and, so far, no where else.	1.03048e-06
NC_009900.1\|WP_012152684.1\|493496_493745_-\|membrane-protein-insertion-efficiency-factor-YidD	gnl\|CDD\|172864	PRK14388, PRK14388, membrane protein insertion efficiency factor YidD.	4.45692e-54
NC_009900.1\|WP_081427919.1\|512713_513232_-\|disulfide-bond-formation-protein-B	gnl\|CDD\|224412	COG1495, DsbB, Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones].	9.83877e-36
NC_009900.1\|WP_012152699.1\|513412_514981_+\|lysine--tRNA-ligase	gnl\|CDD\|234829	PRK00750, lysK, lysyl-tRNA synthetase; Reviewed.	0
NC_009900.1\|WP_041404627.1\|507773_508577_+\|N-acetylmuramoyl-L-alanine-amidase	gnl\|CDD\|225567	COG3023, ampD, N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane].	4.19241e-90
NC_009900.1\|WP_012152685.1\|493737_494241_-\|NADH-quinone-oxidoreductase-subunit-NuoE	gnl\|CDD\|181024	PRK07539, PRK07539, NADH-quinone oxidoreductase subunit NuoE.	2.88654e-92
NC_009900.1\|WP_012152695.1\|504707_505490_-\|enoyl-ACP-reductase-FabI	gnl\|CDD\|168626	PRK06603, PRK06603, enoyl-[acyl-carrier-protein] reductase FabI.	0
NC_009900.1\|WP_014365940.1\|497169_497541_-\|NADH-quinone-oxidoreductase-subunit-A	gnl\|CDD\|180638	PRK06602, PRK06602, NADH:ubiquinone oxidoreductase subunit A; Validated.	6.44083e-56
NC_009900.1\|WP_041404971.1\|494660_495836_-\|NADH-dehydrogenase-(quinone)-subunit-D	gnl\|CDD\|180385	PRK06075, PRK06075, NADH-quinone oxidoreductase subunit D.	0
NC_009900.1\|WP_041404620.1\|492661_493207_-\|DNA-3-methyladenine-glycosylase	gnl\|CDD\|234840	PRK00802, PRK00802, DNA-3-methyladenine glycosylase.	3.44744e-92
NC_009900.1\|WP_041404623.1\|503355_504519_+\|DUF5410-domain-containing-protein	gnl\|CDD\|375184	pfam17422, DUF5410, Family of unknown function (DUF5410). This is a family of unknown function found in Rickettsia.	1.31353e-176

>NC_009900.1|WP_012152692.1|501217_502138_+|site-specific-tyrosine-recombinase-XerD
MEFISQFLEMLLAERALSKNSILSYKRDLFDFHNYLATQKLSELNITTENIRDWIEYLASNDLQARSINRKISTIKSYYKFLISENHTAFNPVLNVDLPKYQNKLPEILSIDQIKSLLEHCSQDNSPEGIRLNAMIHLLYASGFRVSELVSLKLADILTNKTSKGEVRKIFSVLGKGNKERVIVINEQAVISIAKYLAIRDVFVNKAKPRNLIYLFPSSALAGYMTRQNFAILLKSAALYAGLNPEHISPHILRHSFASHLLEGGADLRVIQELLGHADISTTQIYTHLQTNHLKKALLHHPLNKN
>NC_009900.1|WP_041404621.1|498938_499412_-|DUF2155-domain-containing-protein
MKLLKIIFIITICIYFPIFAENLESVTTTEDIENDVFIPLDENHPILNPNDNINDSAEFKNYTNGKIIALNNITATSEEIDFKVGEEKYFGNIKIKLHRCIKNLDPYNEDNYLLMTITEYKIDEDPNLLFQGWMISSSISLSMFEHPIYEIFAKDCF
>NC_009900.1|WP_012152690.1|497699_498938_-|O-antigen-ligase-family-protein
MQYLISSLIFLIPSLGMLAGLSAAATVTIFLLISFLRGINNHHCERLKGAWQSSNNVIPWLDHGIQKIKKDWIPLQTSGMTMLFTTWCFISCLFATHLINSLATFTQVFILLFLGFAVSNSAPFQNRLQLKKVLIFGILTAILLFFIEYSSYGFLTRIFKASFGLYMLDRGCALLSITAWVAIIILLSNGKKRYALMLYILVLYLLSISDSLASFLGFGIGGVIFIVTRFMKPIFFKLIAISLITGSLLFPVLAKQIEPRDLSEKYLATQPSAAHRLFIWHFVVNKIIEKPILGYGLASSKYIEAGDSEMIDYNGEKWHPLPLHPHNNILQITLELGIIGLILFLCLVYKYLKQISNLENKNFKAISYACFINYYIIGMISYNIWQIWWISSGIWVLVLMKLLVKPDIVIDN
>NC_009900.1|WP_014365940.1|497169_497541_-|NADH-quinone-oxidoreductase-subunit-A
MLQNSELLQEYLPIAIFFGIAVLVSGLIMILPNLLSTKKYNKDKLEPYECGFEPFSDARSKFDIRFYLVAILFIIFDLEIAFLVPWAISLNTIGKIGFFSMMFFLFVLIIGFIYEWKKGALDW
>NC_009900.1|WP_012152688.1|496640_497165_-|NADH-quinone-oxidoreductase-subunit-B
MKNNFYQEDELLSNELSNRGFLLTKVDNVIGWARANSLWPMTFGLACCAVEMMQAAASRYDMDRFGMLFRPSPRQSDLMIVAGTLTNKMAPALRKVYDQMAEPKWVLSMGSCANGGGYYHFSYSVVRGCDRIVPVDVYVPGCPPTAEALIYGLMQLQKKIKRTTGFKYDTRQTH
>NC_009900.1|WP_012152687.1|495934_496663_-|NADH-quinone-oxidoreductase-subunit-C
MTLDKLIERLAAKSSILITPITVKDYLAYKIEPNFLLLFLKALKESEELRFTLLTDLFGADFPQNNVVNSVGLGYKEQGAKPITNRRATSDNVGESKSIDYKRFEVVYNLLSLKLNKRLIIKVYISEKETIPSAMNIFSAACWYEREVYDMYGVNFEGNDDKRRILTDYEFEGHPLRKDFPLTGYTQVKYDEKLKKVAYEPVDLDIEYREFDFSSHWHSPSYVLPGDEKATDVIPAKAGIQK
>NC_009900.1|WP_041404971.1|494660_495836_-|NADH-dehydrogenase-(quinone)-subunit-D
MTNNTKTITLNLGPQHPATHGVLRLILEMDGEVVNNAVPHIGLLHRGTEKLIEHKTYLQAIPYFDRLDYVSPMCQEHAFALAVESLLECEVPRRAQFIRVLFSELTRILNHTLNIGSQALDIGATTPLLWLFEEREKIMEFYEHVSGSRMHSNYFRPGGVAADLPEGLLEDIDKFIEQFPPKLHDIESLLNENRLWKQRLVDIGVASQKEAMDWGFSGPMLRGSGIAWDLRKSNPYDVYDEMDFKVPIGKNGDCYDRYFVRMLEMYESIKIIKQCIEKMPKGAVKTDDPKLTPPTRAKMKESMEAMIHHFKLYTEGYDVPAGETYKAVEAPKGEFGVYLYSQGGNRPYRCRIKAPGFAHLQGLDFMSKGHLMADVITIIATLDIVFGEIDR
>NC_009900.1|WP_012152685.1|493737_494241_-|NADH-quinone-oxidoreductase-subunit-NuoE
MNTKITNFTFDKKNLNLAEEIIKKYPPHGKRSAILPLLDLAQRQNGGWLPVPAIEYVANMLEMPYIRAYEVATFYTMFNLKQVGKYHIQVCTTTPCWLRGSDDIMKICEKKLGVKLKETTEDQKFTLSEIECLGACVNAPVVQINDDYYEDLTQEKMEKIIDKLQND
>NC_009900.1|WP_012152684.1|493496_493745_-|membrane-protein-insertion-efficiency-factor-YidD
MTRILLLLLRFYQYFISPLLSNNCRFHPTCSEYAKEAISMHGSIKGLWLTFKRIIKCQPFCDGGYDTVPISIKNSKPLNKKI
>NC_009900.1|WP_041404620.1|492661_493207_-|DNA-3-methyladenine-glycosylase
MNKLIPLPREFFARDTNVVSTELIGKALSFQGKTAIITETESYIGQNDPACHAARGRTKRTDIMFGPAGFSYVYLIYGMYYCLNFVTEAKGFPAATLIRGVHVISPENLYLNGPGKLCKYLGINISHNKCDLINNNEFFVGDIGLKLPYSTTARIGITKGTDKLWRYVITDITNLISQYNV
>NC_009900.1|WP_041404623.1|503355_504519_+|DUF5410-domain-containing-protein
MAPKNKKETVNTETKNLANLVIQEIGDENFDFGVLQKMQQAFSTASKQKQREAFISLLDKKLNKEQLHKLNQAIMENANELMPDNDPNFVCRTPNNKVFQEILLLEAKRSGMKAKFNDKGELQSLDVKDITQGILDHYRILQEKFYPKRDSKDLIDSRIAQSINFLLYAPLFRESDIYTKLGLKSAEIEREIQDPNGKYAKQLVDAKIGTNINFNAKENLENKVHEGKETKISSIIEKAITKLEKDKKVNIEDKRQGEIKRHLSKSLEGASDYILTFKKNDLVDVIYQGLDKRQTWWSKIVNYIGIKSYSISKENLEKIGTIINSEMKNSHTPLKIEVQEQLEQISKELNRLNNPALPSEAKKAQAKSKKPPVPPKPERLKKRNHGL
>NC_009900.1|WP_041404624.1|504518_504713_+|palindromic-element-RPE4-domain-containing-protein
MILLYDLKKLSSHDLFTGSKILILLVFFIVFMDPVVKPRGDTVDFIGPHKQAFCGNDINPYNNL
>NC_009900.1|WP_012152695.1|504707_505490_-|enoyl-ACP-reductase-FabI
MTTGLLQGKKGLITGIANNMSISWAIAQLAKKHGAELWFTYQSEVLEKRVKPLAEEIGCNFVSELDVTNPKSISNLFDDIKEKWGSFGFLLHGMAFADKNELKGRYVDTSLENFHNSLHISCYSLLELSRSAEALMHDGGSIVTLTYYGAEKVIPNYNVMGVAKAALEASIKYLANDMGENNIRVNAISAGPIKTLASSAIGDFSTMLKSHAATAPLKRNTTQEDVGGAAVYLFSELSKGVTGEIHYVDCGYNIMGSNKL
>NC_009900.1|WP_041404625.1|505565_507083_+|apolipoprotein-N-acyltransferase
MYKPKIICLLLGILSGLVFAPTFFVPALLTLSYLCYIVQKSENWQEATKFGYLFGFGHFLSGIYWISIGVSVYIADFWWAIPFALFGLPIVLACFISASCTLSFFAKNNKYYQFIFCLCWVLFEWVRSWIFTGLPWNLIGYAFSFSDILIQPLSIIGIYGLSFIVIYIATSAYPLFSKQFTQLKILLASSVLVLTVIVIYGAVRLSNNHTNFTDIKVRLVQPSIPQTEKWNEEEFWHNLMLHINLSENLEPTDLIIWSEAALVVVPDDIPQVKSKLLKMLNSTNAILITGGISDNKKQGDEFELYSAMYALDKNNHKLFEYHKSHLVPFGEYMPLKKILPFKKLTHGLIDYKEGNGGLVYLEKYNLKIKPLICYESIFPDFVRTNNEIADVIINITNDAWYGKSSGPYQHFHISRSRAVENGLPMIRVANNGISAIVDPFGRTIKKLNLNEINYTQGLIPKKLISPTIFSQFGNFTILLLIVFILLINYLLALILDNQRVLALLY
>NC_009900.1|WP_041404627.1|507773_508577_+|N-acetylmuramoyl-L-alanine-amidase
MSKSKAIENNGISNTNSPNGKYMAPRPEGVKPTCVVITYSVSKDIKAVREVLDERGASVHYIIDKDGTQKEYHNDLTDQAFYAGKSSWKGEVGVNKFGIGVMLINDAKSDFPEEQIGKLKEFLKDVTERYPDLDLKNDLVGLGEVTVNREGNAHIAPGSKFPWKELAAAGFGRYFETTQEQKSELLLSLDSTGEKVNILQENLKEYGYGVESTSTFDQFTQQAVRVFNDRYGTGLPNEEPPVSWTEAGQDVLSQLLGQTVLEQTENA
>NC_009900.1|WP_041404628.1|512454_512667_-|ankyrin-repeat-domain-containing-protein
MLARIGNVNNVRLLLSQGADVNALDAKGNTALFYASTKEIAKILLDKGASFEVEHEYLYSPIHICGNNRT
>NC_009900.1|WP_081427919.1|512713_513232_-|disulfide-bond-formation-protein-B
MPFNTIINYIRKDSYKVLHLGLIAISIIALATAYIAEYIFHYTPCPLCVYERFPYLTLIKICLTALIIRQLSKYTLIFILLTILSSCILSTYHSFVERGIVQPSALCSSMIRIPKGLSIQHIKQMFYSQPITSCTKPAIKIFGISMTEYNLLLNIGLLICLLLVWFYSKSNK
>NC_009900.1|WP_012152699.1|513412_514981_+|lysine--tRNA-ligase
MSEIWEDAIKSNAWPFVEAKKILDSLNGKIPEKGYVLFETGYGPSGLPHIGTFGENARMVMVQKAFEQLSDIPTKLICFSDDMDGLRKVPSNIPNPEMVAQYMDMPLTSIPDTFGECESYGHYMNAKLRSFLDKFGFEYEFYSSTNCYKAGMFDEMLIMVLEKYDEIMELMLPTFREERKATYSPCMPICPKTGKVLQVPIEKWDAKAGTVTYKDEAGNYIEVPVTGGHCKLQWKPDFGMRWAALKVDYEMYGKDHLANARLYSEICRILGGKPPVQLCYELFLDENGEKISKSKGNSISVDDWLKCAPVESMALFMYQNPTRAKRLFFDVIPKNVDKYITFNQKYHLEEDRAKRFANPVYHIHHGNVPQIETFGITYSLLLNLTSVCNPSDKSVLWGFISKYEPKATPNTSPYLDHLAEFAIRYYNDFIKAHKSYLSPSEKHKVILQDILDMLSDIADQTEAEAIQKAIYDIGMKAGYENLRDYFKDLYQILLGQNEGPRLGTFIKLYGVQEMKKLVEGQL
>NC_009900.1|WP_012152700.1|515110_516043_+|AEC-family-transporter
MNEIFCSTLPIFLITLLGSIIKNKWLTSEEFWRGIEKLSYFVLFPAMLFNYVSTADLSVASISKLVAALIISTILVSIALIIYQKKYNIDKVQFTSIFQGSIRYNSYIFFGVSSPLLGPSGLSIVAVISSYMIIFTNILSVMIFAYYIPNKSVTNTIRTSFVLMMKLIVRNPLIIASLVGFVFNYSNLELHLGLKKTLDSLSNAALAIGMLNVGAGLNFTIRQELLHNVMLTSFVKLVAFPLVSVVVLWLMSIDGLDRSVGILYSCLPCASTAYVLSRQLDGDPDSMASIITFTTFFSVVTISIIMYIMG
>NC_009900.1|WP_041404974.1|516181_518485_+|NADP-dependent-malic-enzyme
MDEMNKINYAKALEYHEKDKPGKIAISATKSLVTQQDLSLAYSPGVAAPCLEIAKNLEDVYKYTARGNLVAVISNGTAVLGLGNLGAAASKPVMEGKAVLFKKFADIDAIDLEVNTEDPEEFINAVKYLRYSFGGINLEDIKAPECFIIEEKLKSLMDIPVFHDDQHGTAIITAAGLINAAYLTNRKLEDLKIVVNGAGAAAIACIDLLIALGADKSKIIVCDTKGVVYKGRLEGMNKWKELYASDTKFRTLAESLNNADVFIGLSVKGAVTKDMVSRMASNPIIFAMANPDPEITPEDIKLVCDDAIIATGRSDYNNQINNVMGFPYIFRGALDVRAKTINTEMKIAAAKAIADLARRPVPEEVYKAYSGRKMVFGKEYIIPVPFDPRLITVVAAAVAIAAIESGVARVKDFSIGKYKKELGSRLNPTANYMNFLAEKIHNAPLKRIVFAEGEEEEVIAAALMMRDKKYGHPIIIGRVERIEATLKKIGQAISLDGIQIMNAALSDSLEKYTDYLYKRLQRKGYLYRDCAKLVKTDKNIFAACMLACGDGDALLTGVTKSYIDSLEDIMKVISPKTNRSILGYSIMIAKDNNIIIADNCITEYPNSWELAQIATQTAEIAKNMGITPRVALLSFSTFGNSSKAKTARIREAVNILDNFSKDKEELSGMKVDFEYDGEMSVKVALDGDLRKLYKFCRLSGSANVLIMPGLNSAAISTELLQAFSSNSFIGPITNGFEKPVQILQATATANEILKIATFACVEAIKEV

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

525567 : 583011

Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage(11.11%)

transposase,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041404978.1\|525567_525960_+\|transposase	IS200/IS605 family transposase	W0UUZ0	Sulfolobus_monocaudavirus	2.2e-17	35.2
WP_041404634.1\|525985_527080_-\|transposase	IS481 family transposase	E9P643	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	7.4e-132	65.5
WP_187145907.1\|527791_528043_+	ankyrin	NA	NA	NA	NA
WP_012152708.1\|528522_530049_-	nucleotide exchange transporter Tlc2	NA	NA	NA	NA
WP_041404636.1\|530257_531871_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.7e-140	47.9
WP_012152710.1\|531873_532614_-	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_012152711.1\|533371_533683_-	NUDIX domain-containing protein	NA	NA	NA	NA
WP_012152712.1\|533816_535403_+	cbb3-type cytochrome c oxidase subunit I	NA	NA	NA	NA
WP_012152713.1\|535395_535965_+	GTP cyclohydrolase I FolE	A0A2I7S8W4	Vibrio_phage	3.4e-35	45.3
WP_041404980.1\|536124_537411_+\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_041404637.1\|537618_538587_+	Fic family protein	A0A1V0E025	Clostridioides_phage	6.8e-12	26.5
WP_014365907.1\|538777_538984_+	hypothetical protein	NA	NA	NA	NA
WP_014365906.1\|538988_539603_+	Holliday junction branch migration protein RuvA	NA	NA	NA	NA
WP_041404638.1\|540089_540290_+	hypothetical protein	NA	NA	NA	NA
WP_041404639.1\|540803_541835_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.2e-06	31.6
WP_041404640.1\|541827_543591_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.0e-61	32.4
WP_041404641.1\|543769_545014_+	AmpG family muropeptide MFS transporter	NA	NA	NA	NA
WP_041404642.1\|545193_546114_+	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	1.1e-27	32.9
WP_041404643.1\|546283_547246_-	septal ring lytic transglycosylase RlpA family protein	F5B3X9	Synechococcus_phage	1.5e-14	49.4
WP_041404644.1\|547223_547841_-	BON domain-containing protein	NA	NA	NA	NA
WP_012152724.1\|548048_548591_-	septation protein A	NA	NA	NA	NA
WP_014365896.1\|548615_549464_-	FTR1 family protein	NA	NA	NA	NA
WP_041404645.1\|549473_549854_-	cupredoxin domain-containing protein	NA	NA	NA	NA
WP_041404646.1\|550059_551055_-	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_012152728.1\|551194_551821_+	dioxygenase	NA	NA	NA	NA
WP_041404647.1\|552028_552688_+	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_012152730.1\|552837_553752_+	S49 family peptidase	A0A075DXA6	Acinetobacter_phage	1.3e-15	29.1
WP_012152731.1\|553753_554200_+	dUTP diphosphatase	A0A1Q1PNN8	Noumeavirus	1.1e-36	58.2
WP_041404648.1\|554422_556384_+	lytic transglycosylase domain-containing protein	A0A0S2SXL7	Bacillus_phage	4.0e-11	37.0
WP_041404649.1\|556469_557435_+	hypothetical protein	NA	NA	NA	NA
WP_187145899.1\|557426_557588_-	palindromic element RPE4 domain-containing protein	NA	NA	NA	NA
WP_041404650.1\|557647_558595_+	LD-carboxypeptidase	NA	NA	NA	NA
WP_041404651.1\|558817_561334_-	PD-(D/E)XK nuclease family protein	NA	NA	NA	NA
WP_041404652.1\|561617_561866_+	hypothetical protein	NA	NA	NA	NA
WP_012152737.1\|561898_562627_-	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	NA	NA	NA	NA
WP_041404653.1\|562833_564432_-	cytochrome c oxidase subunit I	R9VX24	Flavobacterium_phage	8.1e-10	39.6
WP_041404654.1\|565044_565992_-	cytochrome c oxidase subunit II	NA	NA	NA	NA
WP_014408553.1\|566073_566628_-	adenylyltransferase/cytidyltransferase family protein	A0A0K0KVL9	Prochlorococcus_phage	1.9e-06	43.7
WP_041404981.1\|566812_568177_+	peptidoglycan DD-metalloendopeptidase family protein	G9BW84	Planktothrix_phage	8.1e-19	41.0
WP_049749355.1\|568373_569030_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_012152742.1\|569132_569384_+	membrane lipoprotein lipid attachment site-containing protein	NA	NA	NA	NA
WP_075807946.1\|569438_569507_-	hypothetical protein	NA	NA	NA	NA
WP_012152743.1\|569555_571052_+	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_041404655.1\|571184_572318_+	putative lipid II flippase FtsW	NA	NA	NA	NA
WP_012152745.1\|572314_573445_+	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_014365874.1\|573852_574512_+	hypothetical protein	NA	NA	NA	NA
WP_012152747.1\|574916_575261_+	hypothetical protein	NA	NA	NA	NA
WP_012153002.1\|577882_578206_-\|transposase	transposase	NA	NA	NA	NA
WP_041404984.1\|578816_579185_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_148194439.1\|580598_580685_-	RND transporter	NA	NA	NA	NA
WP_081427922.1\|580973_581075_-	palindromic element RPE3 domain-containing protein	NA	NA	NA	NA
WP_041404659.1\|581105_582122_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_012152749.1\|582121_582667_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	E9P639	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	3.6e-34	45.5
WP_081427875.1\|582636_582819_-\|transposase	PD-(D/E)XK nuclease family transposase	A0A1B2LRR6	Wolbachia_phage	3.5e-10	63.3
WP_081427876.1\|582849_583011_-\|transposase	PD-(D/E)XK nuclease family transposase	A0A1B2LRR6	Wolbachia_phage	1.3e-13	67.9

DBSCAN-SWA_2

707772 : 797618

Wolbachia_phage(16.67%)

transposase,tRNA,integrase

attL 702560:702581|attR 787252:787273

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
702560:702581	attL	NA	NA	NA	NA
WP_041404709.1\|707772_708921_+\|integrase	site-specific integrase	A0A0M3LQN1	Mannheimia_phage	3.7e-17	28.3
WP_012152839.1\|709136_709760_+	DUF4065 domain-containing protein	I6R0L8	Salmonella_phage	2.4e-26	41.2
WP_012152840.1\|709756_710017_+	Txe/YoeB family addiction module toxin	NA	NA	NA	NA
WP_041404710.1\|710083_710269_-	hypothetical protein	NA	NA	NA	NA
WP_041404711.1\|710479_710788_+	hypothetical protein	NA	NA	NA	NA
WP_012152842.1\|710787_711342_+	conjugative transfer protein	NA	NA	NA	NA
WP_012152843.1\|711338_711794_+	hypothetical protein	NA	NA	NA	NA
WP_041404712.1\|711753_712086_+	hypothetical protein	NA	NA	NA	NA
WP_012152845.1\|712110_713523_+	TraB/VirB10 family protein	NA	NA	NA	NA
WP_012152846.1\|713522_713762_+	hypothetical protein	NA	NA	NA	NA
WP_012152847.1\|713761_716281_+	TraC family protein	NA	NA	NA	NA
WP_041404998.1\|716515_717955_+	AAA family ATPase	NA	NA	NA	NA
WP_041404713.1\|718820_719027_+	type II toxin-antitoxin system prevent-host-death family antitoxin	NA	NA	NA	NA
WP_041404714.1\|719029_719998_+	TraU family protein	NA	NA	NA	NA
WP_041404999.1\|720027_720450_+	type-F conjugative transfer system pilin assembly protein TrbC	NA	NA	NA	NA
WP_041404715.1\|720446_722246_+	conjugal transfer protein TraN	NA	NA	NA	NA
WP_187145869.1\|722250_723123_+	conjugal transfer protein TraF	NA	NA	NA	NA
WP_041405000.1\|723143_724478_+	conjugal transfer protein TraH	NA	NA	NA	NA
WP_012152854.1\|724556_727286_+	conjugal transfer protein TraG N-terminal domain-containing protein	NA	NA	NA	NA
WP_041404717.1\|727296_728466_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_041404718.1\|728470_730162_+	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_012152857.1\|730391_731435_-\|transposase	Rpn family recombination-promoting nuclease/putative transposase	Q2A0A7	Sodalis_phage	3.6e-27	35.5
WP_012152858.1\|731478_735615_-	AAA family ATPase	Q7T5H7	Cryptophlebia_leucotreta_granulosis_virus	3.3e-07	23.8
WP_012152859.1\|736268_737219_+\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	9.3e-22	31.5
WP_187145870.1\|737717_738170_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_041404719.1\|738540_739023_-	hypothetical protein	NA	NA	NA	NA
WP_012152861.1\|739024_739786_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	9.7e-30	36.2
WP_049749362.1\|739778_740378_-	hypothetical protein	NA	NA	NA	NA
WP_041404948.1\|740442_740880_-\|transposase	IS200/IS605 family transposase	G9CU69	Helicobacter_phage	6.4e-18	36.8
WP_081427883.1\|742460_742772_+\|transposase	transposase	NA	NA	NA	NA
WP_012152863.1\|742737_743607_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	5.6e-58	41.5
WP_187145871.1\|743851_744700_-\|transposase	IS30 family transposase	NA	NA	NA	NA
WP_041404634.1\|745064_746159_+\|transposase	IS481 family transposase	E9P643	Wolbachia_endosymbiont_wVitB_of_Nasonia_vitripennis_phage	7.4e-132	65.5
WP_049749363.1\|746170_746764_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.3e-25	34.7
WP_041404722.1\|746747_746975_-	hypothetical protein	NA	NA	NA	NA
WP_012152866.1\|747229_748666_+\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	1.1e-77	35.5
WP_012152867.1\|748782_757167_-	hypothetical protein	NA	NA	NA	NA
WP_187145872.1\|757299_757470_-	hypothetical protein	NA	NA	NA	NA
WP_041404723.1\|757546_757819_+	conjugal transfer protein TraD	NA	NA	NA	NA
WP_012152869.1\|757844_758504_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	NA	NA	NA	NA
WP_041404724.1\|758662_759574_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	9.3e-11	24.3
WP_012152871.1\|759967_760768_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A1S5PRR3	Streptococcus_phage	4.9e-32	31.8
WP_012152872.1\|761011_762733_-	hypothetical protein	NA	NA	NA	NA
WP_148194443.1\|763087_763162_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_041404725.1\|763574_764234_+	(d)CMP kinase	NA	NA	NA	NA
WP_012152875.1\|764381_766088_+	30S ribosomal protein S1	NA	NA	NA	NA
WP_041405004.1\|766244_766850_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	4.2e-60	62.0
WP_041404726.1\|769151_769358_+	hypothetical protein	NA	NA	NA	NA
WP_014408694.1\|769565_770594_+	type 2 isopentenyl-diphosphate Delta-isomerase	NA	NA	NA	NA
WP_041405005.1\|770921_771137_-	hypothetical protein	NA	NA	NA	NA
WP_148194410.1\|771133_771586_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_041404727.1\|771650_772118_-	DUF1016 family protein	Q9JMP5	Wolbachia_phage	1.0e-42	50.6
WP_156405180.1\|772207_772474_-	DUF1016 family protein	Q9JMM6	Wolbachia_phage	1.1e-20	54.5
WP_041405006.1\|772609_772834_-	hypothetical protein	NA	NA	NA	NA
WP_041404729.1\|773174_773384_-	hypothetical protein	NA	NA	NA	NA
WP_012152882.1\|774547_775294_-	NTP transferase domain-containing protein	A0A2K9L821	Tupanvirus	7.3e-30	37.1
WP_041405007.1\|775290_776052_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_012152884.1\|776262_776388_-	50S ribosomal protein L36	NA	NA	NA	NA
WP_041404731.1\|776566_776872_+	hypothetical protein	NA	NA	NA	NA
WP_187145908.1\|777205_777658_+	hypothetical protein	NA	NA	NA	NA
WP_012152886.1\|777759_778602_+	lytic transglycosylase domain-containing protein	NA	NA	NA	NA
WP_041404733.1\|778606_779092_+	DUF2532 domain-containing protein	NA	NA	NA	NA
WP_148194444.1\|779235_779532_+\|transposase	transposase	NA	NA	NA	NA
WP_187145873.1\|779456_779918_+\|transposase	IS1595 family transposase	NA	NA	NA	NA
WP_041404734.1\|780086_780299_+	hypothetical protein	NA	NA	NA	NA
WP_187145874.1\|780247_780352_+	hypothetical protein	NA	NA	NA	NA
WP_081427885.1\|780631_780811_+	DNA adenine methylase	NA	NA	NA	NA
WP_049749364.1\|780874_781303_+	hypothetical protein	NA	NA	NA	NA
WP_014365735.1\|781921_782620_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_012152890.1\|782775_784155_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	9.9e-49	29.3
WP_144010772.1\|784282_784357_+	palindromic element RPE4 domain-containing protein	NA	NA	NA	NA
WP_041404735.1\|784450_784972_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_014365731.1\|785364_786210_-	ribonuclease D	NA	NA	NA	NA
WP_012150942.1\|786219_787011_-	RMD1 family protein	NA	NA	NA	NA
WP_041404736.1\|787123_788131_+	folate-binding protein YgfZ	NA	NA	NA	NA
787252:787273	attR	NA	NA	NA	NA
WP_041404737.1\|788769_789423_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_041404738.1\|791902_792301_+	histidine kinase	NA	NA	NA	NA
WP_041404739.1\|792356_792506_+	ATP-binding protein	NA	NA	NA	NA
WP_041404740.1\|792676_793666_+	LD-carboxypeptidase	NA	NA	NA	NA
WP_012152897.1\|793662_794718_+	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_014408729.1\|796216_796372_+	hypothetical protein	NA	NA	NA	NA
WP_012152898.1\|796625_797618_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage