CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_009328	Geobacillus thermodenitrificans NG80-2, complete sequence	4 crisprs	cas6,csa3,DEDDh,WYL,cas3,DinG,cas2	0	0	13	0
NC_009329	Geobacillus thermodenitrificans NG80-2 plasmid pLW1071, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_009328_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009328_1

316026-316120

Unclear

Consensus_repeat	Method
GTTTGTATCGTACCTATGAGGGATTGAAAC	CRISPRCasFinder

1 spacers

cas6

The CRISPR arrays of NC_009328_1

>merge|NC_009328|1|316026-316120|CRISPRCasFinder
GTTTGTATCGTACCTATGAGGGATTGAAACTCTGTCGATGAACTGAATTTTTATTTCGCCTGCGGTTTTTATCGTACCTATGAGGGATCGAAACG

>NC_009328|1|1|316026-316120|CRISPRCasFinder
GTTTGTATCGTACCTATGAGGGATTGAAAC	TCTGTCGATGAACTGAATTTTTATTTCGCCTGCG
GTTTTTATCGTACCTATGAGGGATCGAAACG

Protein	Signature genes	Signature genes Name	Protein_function
NC_009328.1\|WP_011886701.1\|309998_310745_-\|lantibiotic-immunity-ABC-transporter-MutE/EpiE-family-permease-subunit	unknown	unknown	gnl\|CDD\|274754
NC_009328.1\|WP_011886707.1\|318004_318448_+\|ASCH-domain-containing-protein	unknown	unknown	gnl\|CDD\|119345
NC_009328.1\|WP_008881427.1\|314276_315179_-\|glycine/betaine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270246
NC_009328.1\|WP_011886704.1\|313126_314260_-\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213262
NC_009328.1\|WP_011886699.1\|308719_309154_-\|NisI/SpaI-family-lantibiotic-immunity-lipoprotein	unknown	unknown	gnl\|CDD\|375645
NC_009328.1\|WP_171355685.1\|325871_326159_+\|DUF997-family-protein	unknown	unknown	gnl\|CDD\|377626
NC_009328.1\|WP_011886708.1\|320211_320865_-\|PspA/IM30-family-protein	unknown	unknown	gnl\|CDD\|224755
NC_009328.1\|WP_011886698.1\|307207_308626_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_009328.1\|WP_008881423.1\|320824_321346_-\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_011886703.1\|312107_312737_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NC_009328.1\|WP_041264183.1\|309208_309997_-\|lantibiotic-immunity-ABC-transporter-MutG-family-permease-subunit	unknown	unknown	gnl\|CDD\|163445
NC_009328.1\|WP_011886706.1\|316171_316918_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_009328.1\|WP_008881422.1\|321515_322889_-\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|380161
NC_009328.1\|WP_008881418.1\|326155_327625_+\|sodium/panthothenate-symporter	unknown	unknown	gnl\|CDD\|236519
NC_009328.1\|WP_148206523.1\|315431_315611_+\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_008881436.1\|306522_307221_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_009328.1\|WP_008881420.1\|323904_325113_+\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273938
NC_009328.1\|WP_011886702.1\|310763_311453_-\|lantibiotic-protection-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|163452
NC_009328.1\|WP_008881425.1\|318800_320039_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NC_009328.1\|WP_011886711.1\|322878_323541_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816

Protein	Function_ID	Function_description	E-value
NC_009328.1\|WP_011886701.1\|309998_310745_-\|lantibiotic-immunity-ABC-transporter-MutE/EpiE-family-permease-subunit	gnl\|CDD\|274754	TIGR03732, lanti_perm_MutE, lantibiotic protection ABC transporter permease subunit, MutE/EpiE family. Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family is largely restricted to gallidermin-family lantibiotic cassettes, but also include orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes. In most species, this subunit is paralogous to an adjacent gene, modeled separately.	4.55661e-92
NC_009328.1\|WP_011886707.1\|318004_318448_+\|ASCH-domain-containing-protein	gnl\|CDD\|119345	cd06553, ASCH_Ef3133_like, ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation, RNA-processing and the regulation of prokaryotic translation.	4.81605e-63
NC_009328.1\|WP_008881427.1\|314276_315179_-\|glycine/betaine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270246	cd13528, PBP2_osmoprotectants, Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 periplasmic-binding protein fold. This family represents the periplasmic substrate-binding component of ABC transport systems that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, bacteria and archaea accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.82169e-141
NC_009328.1\|WP_011886704.1\|313126_314260_-\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213262	cd03295, ABC_OpuCA_Osmoprotection, ATP-binding cassette domain of the osmoprotectant transporter. OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.45669e-163
NC_009328.1\|WP_011886699.1\|308719_309154_-\|NisI/SpaI-family-lantibiotic-immunity-lipoprotein	gnl\|CDD\|375645	pfam18218, Spa1_C, Lantibiotic immunity protein Spa1 C-terminal domain. This is the C-terminal domain found in SpaI present in Bacillus subtilis. SpaI is an immunity lipoprotein that protects the Gram-positive bacteria against their own lantibiotics, in this case subtilin. SpaI together with the ABC transporter SpaFEG protects the membrane from subtilin insertion.	2.17556e-40
NC_009328.1\|WP_011886708.1\|320211_320865_-\|PspA/IM30-family-protein	gnl\|CDD\|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	8.14054e-24
NC_009328.1\|WP_011886698.1\|307207_308626_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.4216e-40
NC_009328.1\|WP_011886703.1\|312107_312737_-\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	2.54248e-80
NC_009328.1\|WP_041264183.1\|309208_309997_-\|lantibiotic-immunity-ABC-transporter-MutG-family-permease-subunit	gnl\|CDD\|163445	TIGR03733, lanti_perm_MutG, lantibiotic protection ABC transporter permease subunit, MutG family. Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family is largely restricted to gallidermin-family lantibiotic cassettes, but also include orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes. In most species, this subunit is paralogous to an adjacent gene modeled separate by TIGR03732, while in some species only one subunit is found.	7.65493e-91
NC_009328.1\|WP_011886706.1\|316171_316918_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	5.44909e-33
NC_009328.1\|WP_008881422.1\|321515_322889_-\|GHKL-domain-containing-protein	gnl\|CDD\|380161	NF033092, HK_WalK, cell wall metabolism sensor histidine kinase WalK. This model describes WalK as found in Staphylococcus aureus (sp\|Q2G2U4.1\|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.	3.15358e-73
NC_009328.1\|WP_008881418.1\|326155_327625_+\|sodium/panthothenate-symporter	gnl\|CDD\|236519	PRK09442, panF, sodium/pantothenate symporter.	0
NC_009328.1\|WP_171355685.1\|325871_326159_+\|DUF997-family-protein	gnl\|CDD\|377626	pfam06196, DUF997, Protein of unknown function (DUF997). Family of predicted bacterial membrane protein with unknown function.	1.33396e-26
NC_009328.1\|WP_008881436.1\|306522_307221_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.10661e-75
NC_009328.1\|WP_008881420.1\|323904_325113_+\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	2.0573e-92
NC_009328.1\|WP_011886702.1\|310763_311453_-\|lantibiotic-protection-ABC-transporter-ATP-binding-protein	gnl\|CDD\|163452	TIGR03740, galliderm_ABC, gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit. Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.	1.39807e-139
NC_009328.1\|WP_008881425.1\|318800_320039_-\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.70595e-112
NC_009328.1\|WP_011886711.1\|322878_323541_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.92289e-78

>NC_009328.1|WP_148206523.1|315431_315611_+|hypothetical-protein
MTPMLPPPRQFTGLPSGLAKLAFVIAESLQPMAKKMKQRQTAGGQEVALGRLLFGCFET
>NC_009328.1|WP_008881427.1|314276_315179_-|glycine/betaine-ABC-transporter-substrate-binding-protein
MLRKWFMSLLAVGLVLGLAACSGKSDAKGKIVITGKKFTEQMILTHVLAEYVKANTDLDVEVKESLGGAFMLQQAIENGDIDMYVEYTGTGYLNILKQPYDPTKTPEQIYNETKKLYKEKYNIAWLKSLGFNNTYALAMRRDLAEKLGVKTYSDLVNHSSSLTFGSDAEFFERSDGYDGLVDTYGFHFKKTVNIDPDLQYEAAKNGKIDVITAYTTDARIKKYDLVVLKDDKQYFPPYYAVPIIRQEVLDANPGLEEKLNQLANILTDEKMMELNGEVNLEGKQPRKVAIDFLKSEGLID
>NC_009328.1|WP_011886704.1|313126_314260_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MIRFENVTKQYEDGFVALKNINLEIRKGELVALIGPSGCGKTTTMRMINRLIEPTSGKVYIDGQDISELDPVELRRNIGYVIQQIGLFPHMTIAENIALVPKLKKWEKHAYEKRVDELLELVGLDPATFKHRYPSELSGGQQQRVGVVRALAAEPDIILMDEPFSALDPISREQLQDDIIRLQEEIHKTIVFVTHDMDEAIKIADRIALMKDGEIVQFATPDQMLRRPANSFVREFIGEDRLQMRTRQTAVPTAEDLMSDDVATISPRRGLAEAFRLMKARKVDSLVVVDKKRSFLGIVTLKQIEQRYNEEHLLVADIADYDVTTLQKEAGVTDVAALFQDSDVRIIPVLDGDRLVGGITRSSMMRALAEWTFQQHA
>NC_009328.1|WP_011886703.1|312107_312737_-|ABC-transporter-permease
MELLQTFIERQEEIWIAFQEHVLLSAIAMGIAIAVAVPLGVVLTRYRKLAEPIIGIAAIIQTIPSLALLGFMLPIFGIGKLPAIIALTLYALLPILRNTYTGILGVDPALVDAGRGMGMTSRQILWMVELPLSLPVIMAGVRTATVLTIGVAALATFIGAGGLGDLIDRGLRIADKNLILAGAIPAAILAIVFDWLLRKVEKKVTPKGL
>NC_009328.1|WP_011886702.1|310763_311453_-|lantibiotic-protection-ABC-transporter-ATP-binding-protein
MGEYMLETHHVSKAFGKQLVVDDVSIKVKKQTVYGLLGPNGAGKSTLLKMLTGLLRPTKGEIMINGHPWSRKDLKDIGVLIESPALYGNLTAHENLLVHAKLLHLPESRIQEVLNIVGLENTGKKKASQFSLGMKQRLGIAKALLNHPKLIILDEPTNGLDPLGIQDLRKLIQSFTENGITVILSSHILSEVKQLADYIGIIQNGKLRYEGKIDESQDLEKLFVDVVNE
>NC_009328.1|WP_011886701.1|309998_310745_-|lantibiotic-immunity-ABC-transporter-MutE/EpiE-family-permease-subunit
MLNMFESERLKYKRTFAKKLVFIAPLFFVLYAIITMPTVNSTHNYFEYAVFNWWPLIFVPIGTALIASLSTVREKKSGNDKVLRCHDISIVRLWWSKITVIAYYMLLSTIELIILLVLLKWLFPNSLSSATVAVFASLVIWLTSLAYIPIGLFVAERFGMVVSIIVSVIGLALGVVMAAQPYWLFIPWSWGMRMMCPIVGVHPNGVPLEKGSPLLDPSVIPIGLAIALVMFLLLSFLTAVWFARKEVY
>NC_009328.1|WP_041264183.1|309208_309997_-|lantibiotic-immunity-ABC-transporter-MutG-family-permease-subunit
MWFLRLLSSEWIKTKRTAIRMMVIITPIIYSLFMVWYFSHYRTSTFWQMKIYQGFFEVMAVSLPIIISLLTGLMSYQEEKAGSFMNILTGPVSKVQWYVGKLTLLIFIACADILLATILMLFGMKYVLKVAHIHYQLFLQGAMLSIVGSLILFSLHLFISFAFGMGASIAVGSGGFLISALIGATSLGDHVWSYIPWAWAVRLSQFPILMMPEVKQALGAQLLNSFSLSLWEGIAYALLSFIIVTIIGSIWFHRWEGNQPHE
>NC_009328.1|WP_011886699.1|308719_309154_-|NisI/SpaI-family-lantibiotic-immunity-lipoprotein
MKNSILLLMLIGILFIGGCSLVSDLKKTATQNMEIDRKLPKYELNKENLQEIHYQGRTYMIQAAKVDRNQLNKPIGKVAETITINEHHQILSKKELRKIEVIPDQTDEKRTHLNFGWVYSIKGVNPDEEVAVTVNHQFLIAKRK
>NC_009328.1|WP_011886698.1|307207_308626_+|HAMP-domain-containing-histidine-kinase
MKKNKTIKRDFYLLVVKVVLATAISSAVTYLCLIYLIITLATNDVVKPTNYFVKDLDLIEKKVKENEEAIFKGRLIPIHRYSEKIQGEVVDISGKHLYGDREIIDDQVDISQSINREIVKGSYVYRFIPLKHDNAIQAVYVLKAPFGFIINNQNRFEAVLIYAVMFISPLIFFIVYLIFFTSRLYKSLFHNVKLLLQASDHIASGNFDFQVSGLKRKEFIKIQDSFNTMISALKEMVERLAKTDDERKMMVSSIAHDIRTPLTVIQGQIDLIQDLRKLDHFDVTPHLEIIRKNCGKMTMLTDNLSLLYKVENDHFSLNGKEVDVRQILEEKKLEISTMVYHQKSINICFDVNLQKSRYILDEAMLMRVLDNILYNSLRFTKSGEIKLEVYDEKEGNECKIYFRCSDTGTGFKENDTSLLFQPFYQDKQYKNHVGLGLYIAKRIVNHHGGEIWAYNNEKGGATVEFYIKELSD
>NC_009328.1|WP_008881436.1|306522_307221_+|response-regulator-transcription-factor
MNNKKILVVDDDEDICCTIKQYLELHHYQVETVHSGVEALKMINDDFDLIVLDIMMEGIDGMELCTIIRDRVDYPIVFVSAKTLEEDKVQALAIGGDDYITKPFSLKELKARIDSHLRREERIRSNERYLLSSKNITIDLLANEVFCKGKKLPLTKKEYEIVKLLMLNKKVVFSKERIFERVWGIDSDSQLDTVTESIKNIRKKIKAVDPETSYIQTLYGLGYKWDVTDEKE
>NC_009328.1|WP_011886706.1|316171_316918_+|CRISPR-associated-endoribonuclease-Cas6
MRLTITMNGRQGPVSLPLHYQHLLQGLLYRSLESKQLATFLHEIGFRHEKRSFKLFTFSRLFGRHEVDRVKKTIRFLDEFQWHIDTILPELTEQLGQQLLLRREIWLYDQPVEVKSVKMDKVEIRQSTIEVAMLSPLTVYSTYETIDRRKKTHFFGPDDEVFPHLIELNFRHKYQAYYGVPPVERLSIQPVHVHQRHRVVTLFKDMYITGWLGHYRLSSSPEQLTFLYHVGLGSRNSQGFGMFCLTGK
>NC_009328.1|WP_011886707.1|318004_318448_+|ASCH-domain-containing-protein
MNNRIQQFWNDFCKATGQEGIEYKDAFQFGAFPDRLADLVVKGKKTATTSGYVFYELEKEPIPKAGEYYIVLDGQGEPVAVIQIQSVEIVPMNEVTEEFALAEGEGDYRSWWDAHEKFFTESLKEYDMEFSPDMLVVCERFKKVYPK
>NC_009328.1|WP_008881425.1|318800_320039_-|MFS-transporter
MDWKRSVRILWLCNFMVSAGMTMVIPFLSLFLWQMGVTEHHALSMWTGLVFSATFLSAAIMAPIWGMFADKYGQRANLIRAGIGMGLLTACMAFAASPMALLVLRFLVGFFSGFITVSFSYLARIVPKDHSGEALGTLQTGSIAGNIIGPLIGGALSDLFGFRPVFLVTGLCILLTLLPVMFWLEKDPVVPQTKKNKASFKEVFEHRPLIILFIATFLVQIAVLGVNSMMTIFVQSLVGNTSNLAFLSGLASSITGIATIIGAPYLGKLGDRIGQEKTLPILLVLSGLFALPQVWTDNIYALYVWRFLQGLVVGGVWPAIQALINVQSPRRIQGRVFGVTASSRFLGNLTGPTAAGAIASLFSIAYIFAFSSLLLIVTGALVGYAHRRSSSVWRKEMKEKLTTWTHRLHSRH
>NC_009328.1|WP_011886708.1|320211_320865_-|PspA/IM30-family-protein
MGVFRRIKTIVLAEVNEQIDQWEDPIAMTKQYLRELKQQLEQGRQALAQQWVAEQRYATLIAQAEETVEKRNRQAKLALERNEEAVAKLALGDKLLYEKKLETYKQQYETIKAKTAEIVRRLNQLRERYDELAAKQLELTARVNAAKALKQIDTTLASFSADEALRGFARMEERVIALEAEASAARFGTNAVLSPVPFEEEVERELAKWKEAQSTNA
>NC_009328.1|WP_008881423.1|320824_321346_-|hypothetical-protein
MKKLRALALLALIVLAGVSLFHVLTPHEVIVYRRLSVPFDGMHGGLGHHHLIFRVEPRAGWLIPGLLMWFIPLLLVGVGAIWLVAKRSKRWIGWALITLGIAALLPKWVLLGLALAAVYTFGRHQTRKSVAAETWKPTTAPISTDWLDEWEKIVQKEGKTNGCVPPDQNNRSR
>NC_009328.1|WP_008881422.1|321515_322889_-|GHKL-domain-containing-protein
MINNWNEWRQWLRRLGNADLFRRTHWRLTALYSGIFTLFLALFVVIAAALFYWITTSEQEQRITRLAEQEANTIEQFLLKQSNFDLFDDQSLVLFSEDQLFFYVISPTGRLLAGDEVHRRLRPYFLSALSHLDTNEQTPVYLTVSLPKHMPGLARDAARDWRVLTAAHPLVIRGDVVGMLYIGMDVTSFFGVFHWLLIVLIGLAILFLAVGVALSFFMSKRALVPIEEAYERQRQFVADASHELRTPLSVVFSSVEALTLEEDVMKNELAHRLLDRLREELKRITKLMNDLLTLARADAKHAALELAKQTFDFRPHAERTFQLISELAAKKQITMNFHAPEQAMVTADPDKLTQLLYILLDNAIKYTPEGGNVTLSIRTEPKQFVLSVKDTGIGIPPEDIGRIFDRFYRVDKARSRQQGGHGLGLSIAKWIVDAHGGTIHVQSQLGQGTEFLVLLPA
>NC_009328.1|WP_011886711.1|322878_323541_-|response-regulator-transcription-factor
MKVLLAEDDLHLWELIVHLLKKKGIDHIDWVQEGEDAYDYAMAEFYDVVVLDWMLPNGDGVDICRRLRQNGYTGAILILTAKDAVQDRVTGLEAGADDYLVKPFEIDELVARLKALARRTFVPLQEETVTFHGFTLNRTSHTLHRNNEEISLTPREFQLLDLLVQNQGQVVPRETILDRVWGWDADVSMKTIDATIKLLRKKLKDDVIQTVRGVGYKIDK
>NC_009328.1|WP_008881420.1|323904_325113_+|trypsin-like-peptidase-domain-containing-protein
MDMMTFEPTPPPQPKRRGRFVSWMAASVAGAVIGSVATWYVAPKWLNQGNVAQTQLTQTNGKKSETLPLQPTASTNTNMIAAINEVADAVVGVINIQKQADFFSNQVQNTEAGTGSGVIFKKDGNTAYIVTNNHVIEGANEVEVALANGKKVKADIVGADALTDLAVLKIPANGVTKVASFGDSSNVPIGEPVAAIGNPLGLDLSRTVTEGIVSGKRTMPVSTSAGNWEIDVIQTDAAINPGNSGGALINSAGQVIGINSMKIAQMGVEGLGFAIPSENAQPIVEQLMKDGTVKRPYLGVQLVDVADLSADVRNDELKLPSSVTQGAAVTAVEPFSPAAEAGLKSKDVIVAINGDKIDSVSALCKYLYTKTSVDERIKLTIYRDGFETTVSVTLKTKQNNQS
>NC_009328.1|WP_171355685.1|325871_326159_+|DUF997-family-protein
MFSKDPRYKIARKEVWIGIGLVIFNFIWWYGFAYGLGSVPANQYSYIFGFPAWFFYSCILGLIVMSLLVFTVVKFFFKEVPFDEDEIDGEGRGVK
>NC_009328.1|WP_008881418.1|326155_327625_+|sodium/panthothenate-symporter
MNWEVIIPLIIFLLITFSVGVWANKYVSKTNSFLQEYFLGSRELGGFILAMTMMATYGSASSFIGGPGVAYTTGLGWVLLSMAQLPAGYFVLMILGKKFAIAARKYQAITLIDFLKSRYESKWVVLLSALSIIIFLFSAMAAQWVGGARLIESLTGLSYTTALFIFAVSVLVYVIIGGFRAVAMTDAIQGTVMFIGTFILLIATIVAGGGVSNIISELATENPNLITPFGAEGELTPLYVSSFWILVGVGVVGLPQITVRAMSYKNAKAMHRAIIISTVFVGFIMLAMHLIGVFARVIIPGVEIGDKVMPLLTLHVLPAWLAGIVLTAPLAAIMSTVDSLLILVSSSIVKDVYLNYIKPEATEKQIKTVSFGVTTIIGILVFLMALSPPDLLIWLNLFSFGGLEAAFIWPVILGLYWKKGNKYGAIASMIVGVGSYIVIHTYFGNLFGLHTVVVPVLLSCIVYVLTSLITNKTMGMKVDYGLSHQTKEV

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Crispr_ID: NC_009328_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009328_2

317100-317856

Unclear

Consensus_repeat	Method
GTTTGTATCGTACCTATGAGGGATTGAAAC	PILER-CR
GTTTGTATCGTACCTATGAGGGATTGAAAC	CRISPRCasFinder
GTTTGTATCGTACCTATGAGGGATTGAAAC	CRT

11 spacers

cas6

The CRISPR arrays of NC_009328_2

>merge|NC_009328|2|317100-317856|PILER-CR,CRISPRCasFinder,CRT
GTTTGTATCGTACCTATGAGGGATTGAAACTCAGCTATCTTGCATATTCGTTGAACAGAACAAAAGTTTGTATCGTACCTATGAGGGATTGAAACTGGATTTCGAGGAATTGCGAAACCACTTGATGGAGCTAGGGTTTGTATCGTACCTATGAGGGATTGAAACAATGCGGGACATGTCACGACACCGGAATACTAGAAGTTTGTATCGTACCTATGAGGGATTGAAACCATTTGTCGCCGCTTGATTTGCGTTTTGCGCTGCGGGTTTGTATCGTACCTATGAGGGATTGAAACAGTCGGTTTTATGTACATTGTCGCCACTCCTAACATGGTTTGTATCGTACCTATGAGAGATTGAAACCCCCACCTCGCTCCTCGCTACAAATAACGCTCCCGGGTTTGTATCGTACCTATGAGGGATTGAAACTACCAAACAAACCATGCTTTTTTCTCTTCATTGTCGTTTGTATCGTACCTATGAGGGATTGAAACAAAATTTATTAACTGGAAGAACGAAGCGGTTAGCAGAGTTTGTATCGTACCTATGAGGGATTGAAACTCGTCACCCACTCCTTGACGTTTTAGGTAGGCAGGTTTGTATCGTACCTATGAGGGATTGAAACTTACGACGAGTACACATATGACCCGAACGCCGGGGGTTTGTATCGTACCTATGAGGAATGGAAACCCCTCACCGAGTCCGCGCATTTTTTCTCCTAAACCCCGTTTGTATCGTACCTATGAGGAATGGAAAC

>NC_009328|2|1|317100-317856|PILER-CR
GTTTGTATCGTACCTATGAGGGATTGAAAC	TCAGCTATCTTGCATATTCGTTGAACAGAACAAAA
GTTTGTATCGTACCTATGAGGGATTGAAAC	TGGATTTCGAGGAATTGCGAAACCACTTGATGGAGCTAGG
GTTTGTATCGTACCTATGAGGGATTGAAAC	AATGCGGGACATGTCACGACACCGGAATACTAGAA
GTTTGTATCGTACCTATGAGGGATTGAAAC	CATTTGTCGCCGCTTGATTTGCGTTTTGCGCTGCGG
GTTTGTATCGTACCTATGAGGGATTGAAAC	AGTCGGTTTTATGTACATTGTCGCCACTCCTAACATG
GTTTGTATCGTACCTATGAGAGATTGAAAC	CCCCACCTCGCTCCTCGCTACAAATAACGCTCCCGG
GTTTGTATCGTACCTATGAGGGATTGAAAC	TACCAAACAAACCATGCTTTTTTCTCTTCATTGTC
GTTTGTATCGTACCTATGAGGGATTGAAAC	AAAATTTATTAACTGGAAGAACGAAGCGGTTAGCAGA
GTTTGTATCGTACCTATGAGGGATTGAAAC	TCGTCACCCACTCCTTGACGTTTTAGGTAGGCAG
GTTTGTATCGTACCTATGAGGGATTGAAAC	TTACGACGAGTACACATATGACCCGAACGCCGGGG
GTTTGTATCGTACCTATGAGGAATGGAAAC	CCCTCACCGAGTCCGCGCATTTTTTCTCCTAAACCCC
GTTTGTATCGTACCTATGAGGAATGGAAAC

>NC_009328|2|2|317100-317856|CRISPRCasFinder
GTTTGTATCGTACCTATGAGGGATTGAAAC	TCAGCTATCTTGCATATTCGTTGAACAGAACAAAA
GTTTGTATCGTACCTATGAGGGATTGAAAC	TGGATTTCGAGGAATTGCGAAACCACTTGATGGAGCTAGG
GTTTGTATCGTACCTATGAGGGATTGAAAC	AATGCGGGACATGTCACGACACCGGAATACTAGAA
GTTTGTATCGTACCTATGAGGGATTGAAAC	CATTTGTCGCCGCTTGATTTGCGTTTTGCGCTGCGG
GTTTGTATCGTACCTATGAGGGATTGAAAC	AGTCGGTTTTATGTACATTGTCGCCACTCCTAACATG
GTTTGTATCGTACCTATGAGAGATTGAAAC	CCCCACCTCGCTCCTCGCTACAAATAACGCTCCCGG
GTTTGTATCGTACCTATGAGGGATTGAAAC	TACCAAACAAACCATGCTTTTTTCTCTTCATTGTC
GTTTGTATCGTACCTATGAGGGATTGAAAC	AAAATTTATTAACTGGAAGAACGAAGCGGTTAGCAGA
GTTTGTATCGTACCTATGAGGGATTGAAAC	TCGTCACCCACTCCTTGACGTTTTAGGTAGGCAG
GTTTGTATCGTACCTATGAGGGATTGAAAC	TTACGACGAGTACACATATGACCCGAACGCCGGGG
GTTTGTATCGTACCTATGAGGAATGGAAAC	CCCTCACCGAGTCCGCGCATTTTTTCTCCTAAACCCC
GTTTGTATCGTACCTATGAGGAATGGAAAC

>NC_009328|2|1|317100-317856|CRT
GTTTGTATCGTACCTATGAGGGATTGAAAC	TCAGCTATCTTGCATATTCGTTGAACAGAACAAAA
GTTTGTATCGTACCTATGAGGGATTGAAAC	TGGATTTCGAGGAATTGCGAAACCACTTGATGGAGCTAGG
GTTTGTATCGTACCTATGAGGGATTGAAAC	AATGCGGGACATGTCACGACACCGGAATACTAGAA
GTTTGTATCGTACCTATGAGGGATTGAAAC	CATTTGTCGCCGCTTGATTTGCGTTTTGCGCTGCGG
GTTTGTATCGTACCTATGAGGGATTGAAAC	AGTCGGTTTTATGTACATTGTCGCCACTCCTAACATG
GTTTGTATCGTACCTATGAGAGATTGAAAC	CCCCACCTCGCTCCTCGCTACAAATAACGCTCCCGG
GTTTGTATCGTACCTATGAGGGATTGAAAC	TACCAAACAAACCATGCTTTTTTCTCTTCATTGTC
GTTTGTATCGTACCTATGAGGGATTGAAAC	AAAATTTATTAACTGGAAGAACGAAGCGGTTAGCAGA
GTTTGTATCGTACCTATGAGGGATTGAAAC	TCGTCACCCACTCCTTGACGTTTTAGGTAGGCAG
GTTTGTATCGTACCTATGAGGGATTGAAAC	TTACGACGAGTACACATATGACCCGAACGCCGGGG
GTTTGTATCGTACCTATGAGGAATGGAAAC	CCCTCACCGAGTCCGCGCATTTTTTCTCCTAAACCCC
GTTTGTATCGTACCTATGAGGAATGGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_009328.1\|WP_011886713.1\|327628_328858_+\|M20-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349944
NC_009328.1\|WP_011886706.1\|316171_316918_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|273848
NC_009328.1\|WP_011886707.1\|318004_318448_+\|ASCH-domain-containing-protein	unknown	unknown	gnl\|CDD\|119345
NC_009328.1\|WP_008881427.1\|314276_315179_-\|glycine/betaine-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270246
NC_009328.1\|WP_011886704.1\|313126_314260_-\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213262
NC_009328.1\|WP_011886699.1\|308719_309154_-\|NisI/SpaI-family-lantibiotic-immunity-lipoprotein	unknown	unknown	gnl\|CDD\|375645
NC_009328.1\|WP_171355685.1\|325871_326159_+\|DUF997-family-protein	unknown	unknown	gnl\|CDD\|377626
NC_009328.1\|WP_011886708.1\|320211_320865_-\|PspA/IM30-family-protein	unknown	unknown	gnl\|CDD\|224755
NC_009328.1\|WP_011886698.1\|307207_308626_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_009328.1\|WP_008881423.1\|320824_321346_-\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_011886703.1\|312107_312737_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NC_009328.1\|WP_041264183.1\|309208_309997_-\|lantibiotic-immunity-ABC-transporter-MutG-family-permease-subunit	unknown	unknown	gnl\|CDD\|163445
NC_009328.1\|WP_011886701.1\|309998_310745_-\|lantibiotic-immunity-ABC-transporter-MutE/EpiE-family-permease-subunit	unknown	unknown	gnl\|CDD\|274754
NC_009328.1\|WP_008881422.1\|321515_322889_-\|GHKL-domain-containing-protein	unknown	unknown	gnl\|CDD\|380161
NC_009328.1\|WP_008881418.1\|326155_327625_+\|sodium/panthothenate-symporter	unknown	unknown	gnl\|CDD\|236519
NC_009328.1\|WP_148206523.1\|315431_315611_+\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_008881425.1\|318800_320039_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340949
NC_009328.1\|WP_008881420.1\|323904_325113_+\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273938
NC_009328.1\|WP_011886702.1\|310763_311453_-\|lantibiotic-protection-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|163452
NC_009328.1\|WP_011886711.1\|322878_323541_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816

Protein	Function_ID	Function_description	E-value
NC_009328.1\|WP_011886713.1\|327628_328858_+\|M20-family-metallopeptidase	gnl\|CDD\|349944	cd08659, M20_ArgE_DapE-like, Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like. Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE) like family of enzymes catalyze analogous reactions and share a common activator, the metal ion (usually Co2+ or Zn2+). ArgE catalyzes a broad range of substrates, including N-acetylornithine, alpha-N-acetylmethionine and alpha-N-formylmethionine, while DapE catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelate (L,L-SDAP) to L,L-diaminopimelate and succinate. Proteins in this family are mostly bacterial and have been inferred by homology as being related to both ArgE and DapE. This family also includes N-acetyl-L-citrulline deacetylase (ACDase; acetylcitrulline deacetylase), a unique, novel enzyme found in Xanthomonas campestris, a plant pathogen, in which N-acetyl-L-ornithine is the substrate for transcarbamoylation reaction, and the product is N-acetyl-L-citrulline. Thus, in the arginine biosynthesis pathway, ACDase subsequently catalyzes the hydrolysis of N-acetyl-L-citrulline to acetate and L-citrulline.	2.49017e-104
NC_009328.1\|WP_011886706.1\|316171_316918_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	5.44909e-33
NC_009328.1\|WP_011886707.1\|318004_318448_+\|ASCH-domain-containing-protein	gnl\|CDD\|119345	cd06553, ASCH_Ef3133_like, ASC-1 homology domain, subfamily similar to Enterococcus faecalis Ef3133. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation, RNA-processing and the regulation of prokaryotic translation.	4.81605e-63
NC_009328.1\|WP_008881427.1\|314276_315179_-\|glycine/betaine-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270246	cd13528, PBP2_osmoprotectants, Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 periplasmic-binding protein fold. This family represents the periplasmic substrate-binding component of ABC transport systems that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, bacteria and archaea accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.82169e-141
NC_009328.1\|WP_011886704.1\|313126_314260_-\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl\|CDD\|213262	cd03295, ABC_OpuCA_Osmoprotection, ATP-binding cassette domain of the osmoprotectant transporter. OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.45669e-163
NC_009328.1\|WP_011886699.1\|308719_309154_-\|NisI/SpaI-family-lantibiotic-immunity-lipoprotein	gnl\|CDD\|375645	pfam18218, Spa1_C, Lantibiotic immunity protein Spa1 C-terminal domain. This is the C-terminal domain found in SpaI present in Bacillus subtilis. SpaI is an immunity lipoprotein that protects the Gram-positive bacteria against their own lantibiotics, in this case subtilin. SpaI together with the ABC transporter SpaFEG protects the membrane from subtilin insertion.	2.17556e-40
NC_009328.1\|WP_011886708.1\|320211_320865_-\|PspA/IM30-family-protein	gnl\|CDD\|224755	COG1842, PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms].	8.14054e-24
NC_009328.1\|WP_011886698.1\|307207_308626_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.4216e-40
NC_009328.1\|WP_011886703.1\|312107_312737_-\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	2.54248e-80
NC_009328.1\|WP_041264183.1\|309208_309997_-\|lantibiotic-immunity-ABC-transporter-MutG-family-permease-subunit	gnl\|CDD\|163445	TIGR03733, lanti_perm_MutG, lantibiotic protection ABC transporter permease subunit, MutG family. Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family is largely restricted to gallidermin-family lantibiotic cassettes, but also include orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes. In most species, this subunit is paralogous to an adjacent gene modeled separate by TIGR03732, while in some species only one subunit is found.	7.65493e-91
NC_009328.1\|WP_011886701.1\|309998_310745_-\|lantibiotic-immunity-ABC-transporter-MutE/EpiE-family-permease-subunit	gnl\|CDD\|274754	TIGR03732, lanti_perm_MutE, lantibiotic protection ABC transporter permease subunit, MutE/EpiE family. Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family is largely restricted to gallidermin-family lantibiotic cassettes, but also include orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes. In most species, this subunit is paralogous to an adjacent gene, modeled separately.	4.55661e-92
NC_009328.1\|WP_008881422.1\|321515_322889_-\|GHKL-domain-containing-protein	gnl\|CDD\|380161	NF033092, HK_WalK, cell wall metabolism sensor histidine kinase WalK. This model describes WalK as found in Staphylococcus aureus (sp\|Q2G2U4.1\|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.	3.15358e-73
NC_009328.1\|WP_008881418.1\|326155_327625_+\|sodium/panthothenate-symporter	gnl\|CDD\|236519	PRK09442, panF, sodium/pantothenate symporter.	0
NC_009328.1\|WP_171355685.1\|325871_326159_+\|DUF997-family-protein	gnl\|CDD\|377626	pfam06196, DUF997, Protein of unknown function (DUF997). Family of predicted bacterial membrane protein with unknown function.	1.33396e-26
NC_009328.1\|WP_008881425.1\|318800_320039_-\|MFS-transporter	gnl\|CDD\|340949	cd17391, MFS_MdtG_MDR_like, Multidrug resistance protein MdtG and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli multidrug resistance protein MdtG, Streptococcus pneumoniae multidrug resistance efflux pump PmrA, and similar multidrug resistance (MDR) transporters from bacteria. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtG confers resistance to fosfomycin and deoxycholate. PmrA serves as an efflux pump for various substrates and is associated with fluoroquinolone resistance. MdtG-like MDR transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.70595e-112
NC_009328.1\|WP_008881420.1\|323904_325113_+\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	2.0573e-92
NC_009328.1\|WP_011886702.1\|310763_311453_-\|lantibiotic-protection-ABC-transporter-ATP-binding-protein	gnl\|CDD\|163452	TIGR03740, galliderm_ABC, gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit. Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.	1.39807e-139
NC_009328.1\|WP_011886711.1\|322878_323541_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.92289e-78

>NC_009328.1|WP_011886706.1|316171_316918_+|CRISPR-associated-endoribonuclease-Cas6
MRLTITMNGRQGPVSLPLHYQHLLQGLLYRSLESKQLATFLHEIGFRHEKRSFKLFTFSRLFGRHEVDRVKKTIRFLDEFQWHIDTILPELTEQLGQQLLLRREIWLYDQPVEVKSVKMDKVEIRQSTIEVAMLSPLTVYSTYETIDRRKKTHFFGPDDEVFPHLIELNFRHKYQAYYGVPPVERLSIQPVHVHQRHRVVTLFKDMYITGWLGHYRLSSSPEQLTFLYHVGLGSRNSQGFGMFCLTGK
>NC_009328.1|WP_148206523.1|315431_315611_+|hypothetical-protein
MTPMLPPPRQFTGLPSGLAKLAFVIAESLQPMAKKMKQRQTAGGQEVALGRLLFGCFET
>NC_009328.1|WP_008881427.1|314276_315179_-|glycine/betaine-ABC-transporter-substrate-binding-protein
MLRKWFMSLLAVGLVLGLAACSGKSDAKGKIVITGKKFTEQMILTHVLAEYVKANTDLDVEVKESLGGAFMLQQAIENGDIDMYVEYTGTGYLNILKQPYDPTKTPEQIYNETKKLYKEKYNIAWLKSLGFNNTYALAMRRDLAEKLGVKTYSDLVNHSSSLTFGSDAEFFERSDGYDGLVDTYGFHFKKTVNIDPDLQYEAAKNGKIDVITAYTTDARIKKYDLVVLKDDKQYFPPYYAVPIIRQEVLDANPGLEEKLNQLANILTDEKMMELNGEVNLEGKQPRKVAIDFLKSEGLID
>NC_009328.1|WP_011886704.1|313126_314260_-|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MIRFENVTKQYEDGFVALKNINLEIRKGELVALIGPSGCGKTTTMRMINRLIEPTSGKVYIDGQDISELDPVELRRNIGYVIQQIGLFPHMTIAENIALVPKLKKWEKHAYEKRVDELLELVGLDPATFKHRYPSELSGGQQQRVGVVRALAAEPDIILMDEPFSALDPISREQLQDDIIRLQEEIHKTIVFVTHDMDEAIKIADRIALMKDGEIVQFATPDQMLRRPANSFVREFIGEDRLQMRTRQTAVPTAEDLMSDDVATISPRRGLAEAFRLMKARKVDSLVVVDKKRSFLGIVTLKQIEQRYNEEHLLVADIADYDVTTLQKEAGVTDVAALFQDSDVRIIPVLDGDRLVGGITRSSMMRALAEWTFQQHA
>NC_009328.1|WP_011886703.1|312107_312737_-|ABC-transporter-permease
MELLQTFIERQEEIWIAFQEHVLLSAIAMGIAIAVAVPLGVVLTRYRKLAEPIIGIAAIIQTIPSLALLGFMLPIFGIGKLPAIIALTLYALLPILRNTYTGILGVDPALVDAGRGMGMTSRQILWMVELPLSLPVIMAGVRTATVLTIGVAALATFIGAGGLGDLIDRGLRIADKNLILAGAIPAAILAIVFDWLLRKVEKKVTPKGL
>NC_009328.1|WP_011886702.1|310763_311453_-|lantibiotic-protection-ABC-transporter-ATP-binding-protein
MGEYMLETHHVSKAFGKQLVVDDVSIKVKKQTVYGLLGPNGAGKSTLLKMLTGLLRPTKGEIMINGHPWSRKDLKDIGVLIESPALYGNLTAHENLLVHAKLLHLPESRIQEVLNIVGLENTGKKKASQFSLGMKQRLGIAKALLNHPKLIILDEPTNGLDPLGIQDLRKLIQSFTENGITVILSSHILSEVKQLADYIGIIQNGKLRYEGKIDESQDLEKLFVDVVNE
>NC_009328.1|WP_011886701.1|309998_310745_-|lantibiotic-immunity-ABC-transporter-MutE/EpiE-family-permease-subunit
MLNMFESERLKYKRTFAKKLVFIAPLFFVLYAIITMPTVNSTHNYFEYAVFNWWPLIFVPIGTALIASLSTVREKKSGNDKVLRCHDISIVRLWWSKITVIAYYMLLSTIELIILLVLLKWLFPNSLSSATVAVFASLVIWLTSLAYIPIGLFVAERFGMVVSIIVSVIGLALGVVMAAQPYWLFIPWSWGMRMMCPIVGVHPNGVPLEKGSPLLDPSVIPIGLAIALVMFLLLSFLTAVWFARKEVY
>NC_009328.1|WP_041264183.1|309208_309997_-|lantibiotic-immunity-ABC-transporter-MutG-family-permease-subunit
MWFLRLLSSEWIKTKRTAIRMMVIITPIIYSLFMVWYFSHYRTSTFWQMKIYQGFFEVMAVSLPIIISLLTGLMSYQEEKAGSFMNILTGPVSKVQWYVGKLTLLIFIACADILLATILMLFGMKYVLKVAHIHYQLFLQGAMLSIVGSLILFSLHLFISFAFGMGASIAVGSGGFLISALIGATSLGDHVWSYIPWAWAVRLSQFPILMMPEVKQALGAQLLNSFSLSLWEGIAYALLSFIIVTIIGSIWFHRWEGNQPHE
>NC_009328.1|WP_011886699.1|308719_309154_-|NisI/SpaI-family-lantibiotic-immunity-lipoprotein
MKNSILLLMLIGILFIGGCSLVSDLKKTATQNMEIDRKLPKYELNKENLQEIHYQGRTYMIQAAKVDRNQLNKPIGKVAETITINEHHQILSKKELRKIEVIPDQTDEKRTHLNFGWVYSIKGVNPDEEVAVTVNHQFLIAKRK
>NC_009328.1|WP_011886698.1|307207_308626_+|HAMP-domain-containing-histidine-kinase
MKKNKTIKRDFYLLVVKVVLATAISSAVTYLCLIYLIITLATNDVVKPTNYFVKDLDLIEKKVKENEEAIFKGRLIPIHRYSEKIQGEVVDISGKHLYGDREIIDDQVDISQSINREIVKGSYVYRFIPLKHDNAIQAVYVLKAPFGFIINNQNRFEAVLIYAVMFISPLIFFIVYLIFFTSRLYKSLFHNVKLLLQASDHIASGNFDFQVSGLKRKEFIKIQDSFNTMISALKEMVERLAKTDDERKMMVSSIAHDIRTPLTVIQGQIDLIQDLRKLDHFDVTPHLEIIRKNCGKMTMLTDNLSLLYKVENDHFSLNGKEVDVRQILEEKKLEISTMVYHQKSINICFDVNLQKSRYILDEAMLMRVLDNILYNSLRFTKSGEIKLEVYDEKEGNECKIYFRCSDTGTGFKENDTSLLFQPFYQDKQYKNHVGLGLYIAKRIVNHHGGEIWAYNNEKGGATVEFYIKELSD
>NC_009328.1|WP_011886707.1|318004_318448_+|ASCH-domain-containing-protein
MNNRIQQFWNDFCKATGQEGIEYKDAFQFGAFPDRLADLVVKGKKTATTSGYVFYELEKEPIPKAGEYYIVLDGQGEPVAVIQIQSVEIVPMNEVTEEFALAEGEGDYRSWWDAHEKFFTESLKEYDMEFSPDMLVVCERFKKVYPK
>NC_009328.1|WP_008881425.1|318800_320039_-|MFS-transporter
MDWKRSVRILWLCNFMVSAGMTMVIPFLSLFLWQMGVTEHHALSMWTGLVFSATFLSAAIMAPIWGMFADKYGQRANLIRAGIGMGLLTACMAFAASPMALLVLRFLVGFFSGFITVSFSYLARIVPKDHSGEALGTLQTGSIAGNIIGPLIGGALSDLFGFRPVFLVTGLCILLTLLPVMFWLEKDPVVPQTKKNKASFKEVFEHRPLIILFIATFLVQIAVLGVNSMMTIFVQSLVGNTSNLAFLSGLASSITGIATIIGAPYLGKLGDRIGQEKTLPILLVLSGLFALPQVWTDNIYALYVWRFLQGLVVGGVWPAIQALINVQSPRRIQGRVFGVTASSRFLGNLTGPTAAGAIASLFSIAYIFAFSSLLLIVTGALVGYAHRRSSSVWRKEMKEKLTTWTHRLHSRH
>NC_009328.1|WP_011886708.1|320211_320865_-|PspA/IM30-family-protein
MGVFRRIKTIVLAEVNEQIDQWEDPIAMTKQYLRELKQQLEQGRQALAQQWVAEQRYATLIAQAEETVEKRNRQAKLALERNEEAVAKLALGDKLLYEKKLETYKQQYETIKAKTAEIVRRLNQLRERYDELAAKQLELTARVNAAKALKQIDTTLASFSADEALRGFARMEERVIALEAEASAARFGTNAVLSPVPFEEEVERELAKWKEAQSTNA
>NC_009328.1|WP_008881423.1|320824_321346_-|hypothetical-protein
MKKLRALALLALIVLAGVSLFHVLTPHEVIVYRRLSVPFDGMHGGLGHHHLIFRVEPRAGWLIPGLLMWFIPLLLVGVGAIWLVAKRSKRWIGWALITLGIAALLPKWVLLGLALAAVYTFGRHQTRKSVAAETWKPTTAPISTDWLDEWEKIVQKEGKTNGCVPPDQNNRSR
>NC_009328.1|WP_008881422.1|321515_322889_-|GHKL-domain-containing-protein
MINNWNEWRQWLRRLGNADLFRRTHWRLTALYSGIFTLFLALFVVIAAALFYWITTSEQEQRITRLAEQEANTIEQFLLKQSNFDLFDDQSLVLFSEDQLFFYVISPTGRLLAGDEVHRRLRPYFLSALSHLDTNEQTPVYLTVSLPKHMPGLARDAARDWRVLTAAHPLVIRGDVVGMLYIGMDVTSFFGVFHWLLIVLIGLAILFLAVGVALSFFMSKRALVPIEEAYERQRQFVADASHELRTPLSVVFSSVEALTLEEDVMKNELAHRLLDRLREELKRITKLMNDLLTLARADAKHAALELAKQTFDFRPHAERTFQLISELAAKKQITMNFHAPEQAMVTADPDKLTQLLYILLDNAIKYTPEGGNVTLSIRTEPKQFVLSVKDTGIGIPPEDIGRIFDRFYRVDKARSRQQGGHGLGLSIAKWIVDAHGGTIHVQSQLGQGTEFLVLLPA
>NC_009328.1|WP_011886711.1|322878_323541_-|response-regulator-transcription-factor
MKVLLAEDDLHLWELIVHLLKKKGIDHIDWVQEGEDAYDYAMAEFYDVVVLDWMLPNGDGVDICRRLRQNGYTGAILILTAKDAVQDRVTGLEAGADDYLVKPFEIDELVARLKALARRTFVPLQEETVTFHGFTLNRTSHTLHRNNEEISLTPREFQLLDLLVQNQGQVVPRETILDRVWGWDADVSMKTIDATIKLLRKKLKDDVIQTVRGVGYKIDK
>NC_009328.1|WP_008881420.1|323904_325113_+|trypsin-like-peptidase-domain-containing-protein
MDMMTFEPTPPPQPKRRGRFVSWMAASVAGAVIGSVATWYVAPKWLNQGNVAQTQLTQTNGKKSETLPLQPTASTNTNMIAAINEVADAVVGVINIQKQADFFSNQVQNTEAGTGSGVIFKKDGNTAYIVTNNHVIEGANEVEVALANGKKVKADIVGADALTDLAVLKIPANGVTKVASFGDSSNVPIGEPVAAIGNPLGLDLSRTVTEGIVSGKRTMPVSTSAGNWEIDVIQTDAAINPGNSGGALINSAGQVIGINSMKIAQMGVEGLGFAIPSENAQPIVEQLMKDGTVKRPYLGVQLVDVADLSADVRNDELKLPSSVTQGAAVTAVEPFSPAAEAGLKSKDVIVAINGDKIDSVSALCKYLYTKTSVDERIKLTIYRDGFETTVSVTLKTKQNNQS
>NC_009328.1|WP_171355685.1|325871_326159_+|DUF997-family-protein
MFSKDPRYKIARKEVWIGIGLVIFNFIWWYGFAYGLGSVPANQYSYIFGFPAWFFYSCILGLIVMSLLVFTVVKFFFKEVPFDEDEIDGEGRGVK
>NC_009328.1|WP_008881418.1|326155_327625_+|sodium/panthothenate-symporter
MNWEVIIPLIIFLLITFSVGVWANKYVSKTNSFLQEYFLGSRELGGFILAMTMMATYGSASSFIGGPGVAYTTGLGWVLLSMAQLPAGYFVLMILGKKFAIAARKYQAITLIDFLKSRYESKWVVLLSALSIIIFLFSAMAAQWVGGARLIESLTGLSYTTALFIFAVSVLVYVIIGGFRAVAMTDAIQGTVMFIGTFILLIATIVAGGGVSNIISELATENPNLITPFGAEGELTPLYVSSFWILVGVGVVGLPQITVRAMSYKNAKAMHRAIIISTVFVGFIMLAMHLIGVFARVIIPGVEIGDKVMPLLTLHVLPAWLAGIVLTAPLAAIMSTVDSLLILVSSSIVKDVYLNYIKPEATEKQIKTVSFGVTTIIGILVFLMALSPPDLLIWLNLFSFGGLEAAFIWPVILGLYWKKGNKYGAIASMIVGVGSYIVIHTYFGNLFGLHTVVVPVLLSCIVYVLTSLITNKTMGMKVDYGLSHQTKEV
>NC_009328.1|WP_011886713.1|327628_328858_+|M20-family-metallopeptidase
MNNYVTDSTLRLLRDREEVVKLTQALVRIPSVYRPGDPEGNEQKVAQYVANYLKQMGVEVHIEEVEPGRPNVIGIIDSGKPGKTILFEGHTDVVTEGDRSAWTYDPFGAEIVNGRIYGRGTNDTKGNLACMITAVHSLLREKEQWKGKIILCIPCDEEGMMIGIKHFIQRGWAKGVDGAIICEPEENQVCIAQKGAMRIVIRVYGKMAHGAIPLSGINPNTRMAKLICELEQLEKREKERLGKHPLLGWPSITPTILKAPVRGDAQINVIPDQCMTTLDIRTIPGQDHEELCEEIQRIFERLAEEDPDFKGEFEVIENRPWTKTSKDEPIVKAVAEAVRRVTKKEPYYNGVPGATDGTFLHLEGIPIVTIGAGDREIPHQVDEYVDIDELAETTEIYRTAALLFLNEEV

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Crispr_ID: NC_009328_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009328_3

346707-347136

Orphan

Consensus_repeat	Method
GTTTGTATCGTACCTATGAGGGATTGAAAC	PILER-CR
GTTTGTATCGTACCTATGAGGGATTGAAAC	CRISPRCasFinder
GTTTGTATCGTACCTATGAGGGATTGAAAC	CRT

6 spacers

The CRISPR arrays of NC_009328_3

>merge|NC_009328|3|346707-347136|PILER-CR,CRISPRCasFinder,CRT
GTTTGTATCGTACCTATGAGGGATTGAAACGGTATTCTAGGCGTAATCGTCGCTGATGGTAAGGCAGTTTGTATCGTACCTATGAGGGATTGAAACGACGAGATGGAACAAAAAGAATCCCGGCAGGTCGACCGTTTGTATCGTACCTATGAGGGATTGAAACTCGTTCAGGACCGCCGCGATTCGGCCGACGGCCACACGTTTGTATCGTACCTATGAGGGATTGAAACAACGTTGTTTTGTCTTGCAAGTCTTCGATTGTGCAAGTTTGTATCGTACCTATGAGGGATTGAAACTTCGTTACTTTCTAAAGATGAATTGATTCATGCTATTTGTTTGTATCGTACCTATGAGGGATTGAAACAAATGACCTGCGTTTTGATCGGTGTAGGTTTCTGAAGTTTTTATCGTACCTATAAGGGATTGAAAC

>NC_009328|3|2|346707-347070|PILER-CR
GTTTGTATCGTACCTATGAGGGATTGAAAC	GGTATTCTAGGCGTAATCGTCGCTGATGGTAAGGCA
GTTTGTATCGTACCTATGAGGGATTGAAAC	GACGAGATGGAACAAAAAGAATCCCGGCAGGTCGACC
GTTTGTATCGTACCTATGAGGGATTGAAAC	TCGTTCAGGACCGCCGCGATTCGGCCGACGGCCACAC
GTTTGTATCGTACCTATGAGGGATTGAAAC	AACGTTGTTTTGTCTTGCAAGTCTTCGATTGTGCAA
GTTTGTATCGTACCTATGAGGGATTGAAAC	TTCGTTACTTTCTAAAGATGAATTGATTCATGCTATTT
GTTTGTATCGTACCTATGAGGGATTGAAAC

>NC_009328|3|3|346707-347136|CRISPRCasFinder
GTTTGTATCGTACCTATGAGGGATTGAAAC	GGTATTCTAGGCGTAATCGTCGCTGATGGTAAGGCA
GTTTGTATCGTACCTATGAGGGATTGAAAC	GACGAGATGGAACAAAAAGAATCCCGGCAGGTCGACC
GTTTGTATCGTACCTATGAGGGATTGAAAC	TCGTTCAGGACCGCCGCGATTCGGCCGACGGCCACAC
GTTTGTATCGTACCTATGAGGGATTGAAAC	AACGTTGTTTTGTCTTGCAAGTCTTCGATTGTGCAA
GTTTGTATCGTACCTATGAGGGATTGAAAC	TTCGTTACTTTCTAAAGATGAATTGATTCATGCTATTT
GTTTGTATCGTACCTATGAGGGATTGAAAC	AAATGACCTGCGTTTTGATCGGTGTAGGTTTCTGAA
GTTTTTATCGTACCTATAAGGGATTGAAAC

>NC_009328|3|2|346707-347136|CRT
GTTTGTATCGTACCTATGAGGGATTGAAAC	GGTATTCTAGGCGTAATCGTCGCTGATGGTAAGGCA
GTTTGTATCGTACCTATGAGGGATTGAAAC	GACGAGATGGAACAAAAAGAATCCCGGCAGGTCGACC
GTTTGTATCGTACCTATGAGGGATTGAAAC	TCGTTCAGGACCGCCGCGATTCGGCCGACGGCCACAC
GTTTGTATCGTACCTATGAGGGATTGAAAC	AACGTTGTTTTGTCTTGCAAGTCTTCGATTGTGCAA
GTTTGTATCGTACCTATGAGGGATTGAAAC	TTCGTTACTTTCTAAAGATGAATTGATTCATGCTATTT
GTTTGTATCGTACCTATGAGGGATTGAAAC	AAATGACCTGCGTTTTGATCGGTGTAGGTTTCTGAA
GTTTTTATCGTACCTATAAGGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_009328.1\|WP_008881404.1\|345768_346119_+\|DUF2200-domain-containing-protein	unknown	unknown	gnl\|CDD\|337575
NC_009328.1\|WP_008881413.1\|332838_334557_-\|M48-family-metalloprotease	unknown	unknown	gnl\|CDD\|320688
NC_009328.1\|WP_011886720.1\|345011_345368_+\|YxeA-family-protein	unknown	unknown	gnl\|CDD\|227613
NC_009328.1\|WP_011886718.1\|342367_343141_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NC_009328.1\|WP_008881409.1\|338592_339975_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|129571
NC_009328.1\|WP_008881397.1\|350441_351275_+\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|376187
NC_009328.1\|WP_008881410.1\|337597_338518_+\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
NC_009328.1\|WP_011886726.1\|357624_357804_+\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_008881411.1\|335932_337453_+\|flotillin-family-protein	unknown	unknown	gnl\|CDD\|225177
NC_009328.1\|WP_008881301.1\|358299_359532_-\|serine/threonine-transporter-SstT	unknown	unknown	gnl\|CDD\|184190
NC_009328.1\|WP_011886719.1\|343115_344987_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376899
NC_009328.1\|WP_011886725.1\|355960_357430_+\|alanine:cation-symporter-family-protein	unknown	unknown	gnl\|CDD\|376500
NC_009328.1\|WP_008881400.1\|348393_348717_+\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NC_009328.1\|WP_008881398.1\|349262_350066_+\|DUF4097-family-beta-strand-repeat-protein	unknown	unknown	gnl\|CDD\|372574
NC_009328.1\|WP_011886717.1\|340643_342029_-\|L-cystine-transporter	unknown	unknown	gnl\|CDD\|224736
NC_009328.1\|WP_008881412.1\|335374_335911_+\|NfeD-family-protein	unknown	unknown	unknown
NC_009328.1\|WP_008878914.1\|353720_354911_+\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574
NC_009328.1\|WP_008881399.1\|348709_349270_+\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|285278
NC_009328.1\|WP_011886727.1\|359806_361198_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	unknown	unknown	gnl\|CDD\|225174
NC_009328.1\|WP_011886722.1\|351394_351985_+\|GrpB-family-protein	unknown	unknown	gnl\|CDD\|377252

Protein	Function_ID	Function_description	E-value
NC_009328.1\|WP_008881404.1\|345768_346119_+\|DUF2200-domain-containing-protein	gnl\|CDD\|337575	pfam09966, DUF2200, Uncharacterized protein conserved in bacteria (DUF2200). This domain, found in various hypothetical bacterial proteins, has no known function.	1.28653e-79
NC_009328.1\|WP_008881413.1\|332838_334557_-\|M48-family-metalloprotease	gnl\|CDD\|320688	cd07329, M56_like, Peptidase M56-like, integral membrane metallopeptidase in bacteria. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain beta-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	5.64403e-35
NC_009328.1\|WP_011886720.1\|345011_345368_+\|YxeA-family-protein	gnl\|CDD\|227613	COG5294, COG5294, Uncharacterized protein conserved in bacteria [Function unknown].	7.89517e-26
NC_009328.1\|WP_011886718.1\|342367_343141_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	5.70405e-110
NC_009328.1\|WP_008881409.1\|338592_339975_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|129571	TIGR00479, 23S_rRNA_uracil1939-C5-methyltransferase_RlmD, 23S rRNA (uracil-5-)-methyltransferase RumA. This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification].	0
NC_009328.1\|WP_008881397.1\|350441_351275_+\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|376187	pfam18765, Polbeta, Polymerase beta, Nucleotidyltransferase. A member of the nucleotidyltransferase fold found in polymorphic toxins (NTox45) and polyvalent proteins.	7.09181e-08
NC_009328.1\|WP_008881410.1\|337597_338518_+\|diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
NC_009328.1\|WP_008881411.1\|335932_337453_+\|flotillin-family-protein	gnl\|CDD\|225177	COG2268, COG2268, Uncharacterized protein conserved in bacteria [Function unknown].	8.67686e-109
NC_009328.1\|WP_008881301.1\|358299_359532_-\|serine/threonine-transporter-SstT	gnl\|CDD\|184190	PRK13628, PRK13628, serine/threonine transporter SstT; Provisional.	0
NC_009328.1\|WP_011886719.1\|343115_344987_+\|ABC-transporter-permease	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	2.25456e-06
NC_009328.1\|WP_011886725.1\|355960_357430_+\|alanine:cation-symporter-family-protein	gnl\|CDD\|376500	pfam01235, Na_Ala_symp, Sodium:alanine symporter family.	0
NC_009328.1\|WP_008881400.1\|348393_348717_+\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	1.12082e-26
NC_009328.1\|WP_008881398.1\|349262_350066_+\|DUF4097-family-beta-strand-repeat-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	7.1257e-16
NC_009328.1\|WP_011886717.1\|340643_342029_-\|L-cystine-transporter	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NC_009328.1\|WP_008878914.1\|353720_354911_+\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.92572e-79
NC_009328.1\|WP_008881399.1\|348709_349270_+\|DUF1700-domain-containing-protein	gnl\|CDD\|285278	pfam08006, DUF1700, Protein of unknown function (DUF1700). This family contains many hypothetical bacterial proteins and putative membrane proteins.	2.4047e-55
NC_009328.1\|WP_011886727.1\|359806_361198_+\|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	4.68541e-141
NC_009328.1\|WP_011886722.1\|351394_351985_+\|GrpB-family-protein	gnl\|CDD\|377252	pfam04229, GrpB, GrpB protein. This family has been suggested to belong to the nucleotidyltransferase superfamily. It occurs at the C-terminus of dephospho-CoA kinase (CoaE) in a number of cases, where it plays a role in the proper folding of the enzyme.	1.41836e-77

>NC_009328.1|WP_008881404.1|345768_346119_+|DUF2200-domain-containing-protein
MTTHKIYKMSFSKVYPNYIAKAEKKGRTKSEVDEIIRWLTGYTQDELEAQLEKQVDFETFFAEAPQLNPNRVLIKGVICGVRVEEIEDPLMQNIRYLDKLIDELAKGKSMEKILRK
>NC_009328.1|WP_011886720.1|345011_345368_+|YxeA-family-protein
MKKIIGMIIALVVVFVGFFTIVPEEDRDHINPFIPKEVVYVQIYEDPAPHGQRYKYTLTGYTEDGEEKEITFTAGKVLKEKAILKVNAKGSFVEKWEEVQPEELPEKVRGKMDSVPSN
>NC_009328.1|WP_011886719.1|343115_344987_+|ABC-transporter-permease
MTFPQFAYKNITRNLRAYMAFYLSSSFAVMIFFMFAMFIFHPALETGYMNNIAKKGMKFAEWIIFGFSIFFILYSLSTFLKTRKKEFGILTIHGASPKQLRWLITLENVFIGLASIITGILGGTVLAKFFFIAGAYMVKMEPLQLYFPLEALGITVGVFLLLFILISQFMLFTIHSEEVISLLKGSEKPKKEPKPSILFSVLGILFLGTGFGMSLFAGIDMGSAVVITLCTVIGTYLFYSQLSVWMIQLLKRNKKMYRKGINLLWISDLTYRIKDNARLFFIVSIVSAVAFTATGTLATYKLMFSTAETSYAMEFLSYATNQDEKKQLEFIKEKLEQENIDYQQTIFKAIEARQGPMSYPVLVVSHQDWVKQFPELQAPNIHDGEGIYYGEAKRGGYTIVNGNKTKLLTDDQQMSITLQSIEEPVFYLSDILVVDHNTFRQLEQNHELSTMYGFQFENWKESLEISQEIQSQIVGETFNPNAQYFSKAVRYFETVQLPSLSLFIGLFIAIIFFLAAGSFLYFRLFADLYEERKKYKSLAKIGLSEKEMVKISTIQMAILFFLPFLLAIIETGFALHVLQREGGYFHVFQSGVITILGFLGLQIIYFIIMSHSYNKHLKEYVFR
>NC_009328.1|WP_011886718.1|342367_343141_+|ABC-transporter-ATP-binding-protein
MEEVLQVKEINKIYQGKVAFQALTNVSFSVEKGEFIGIMGPSGSGKTTLLNLISTIDKPTSGKVLINGQDPHQLKKERLAEFRRKELGFVFQDFNLLDTLTLEENIMLPLTLENVDPELIEEKVKTISKKLGIDAILTKRTYEVSGGQKQRTAIARAIIHQPKLLLADEPTGNLDSKASKDVMQTLQMINENDQTTMLMVTHDPYAASYCHRVIFIKDGKLYNEIYRGTDQKAFFQQIMDVLSMLGGDRDDFSTVRL
>NC_009328.1|WP_011886717.1|340643_342029_-|L-cystine-transporter
MNIYLIIFNIAILLLLIGVLVYMQKKHVSFSKRVFTALGLGIVFGFALQGVYGAGSAIVQQSTQWFDIVGTGYVKLLQMIVMPLVFISIVMAFTKLSVSNHLGKIATLIIGLLLGTTAIAASIGIMSSLGFQLEAMEIPSGEAEQTRGQELEQKYEQIQNLSFPQKIIELLPANPFLDFTGQRSTSTIAVVIFAAFVGIAYLGVARKQPEQAEMFKKIVDALYAIVMRIVTLVLRLTPYGILAIMSRVTATSDINTIAKLGKFVVASYIALFVMFAIHLIILALAGLNPITYVKKVLPVLSFAFTSRSSAATLPLNVKAQTTALGVPEGIANFAGSFGLSIGQNGCAGIYPAMLAVMIAPTVNIDPTSPSFILTLILVVTISSFGVAGVGGGATFAAILVLSTMNLPVALAGLLISIEPLIDMGRTALNVSGSMTAGVVTSRITKELDVNVYNEETQKLEA
>NC_009328.1|WP_008881409.1|338592_339975_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MAKQQAPVAKNDYYDVTFTDLTHDGLGVAKVDGFPLFVKNALPGERAKVKVIKVKKGYGYGRLIELYEPSPDRVEPPCPVYRQCGGCQLQHLSYEGQLKAKEKQVKEVLARIGKLEHVTVHPVIGMKNPWRYRNKAQVPVGEREGGLIAGFYKERSHEIIDMDACFIQQEKNDVVVQAVKRIAERYGVRPYDELTHRGVLRHIVARYGAATGEVMVVLVTRTERLPHEQEIVRDIIRDIPDVKSIVQNINPERTNVIFGAKTRVLWGSEFITDRIGDIQFAISARSFYQVNPEQTKVLYDKALEYAELTGTETVIDAYCGIGTISLFLAKKAKHVYGVEIVPEAIEDAKRNAALNGITNVTFAVGAAEDVIPRWYEEGIRADCLVVDPPRKGCDAALLETIMAMKPPRVVYVSCNPATLARDLRILEDGGYETIEVQPVDMFPHTAHVESVARLALKIRA
>NC_009328.1|WP_008881410.1|337597_338518_+|diacylglycerol-kinase
MKRARVIYNPTSGRELFKRHLPDVLVRLEKAGYETSCHATEGPGDATKAARQAAEREFDLVVAAGGDGTINEVVNGIANQPYRPKLGVIPVGTTNDFARAIGVPRSIEGACEVIATGEPVAIDIGSVTNEDQTRYFINIAGGGRLTELTYEVPSKLKTMLGQLAYYLKGIEMLPSIKATEAQIEYDGKLFEGEIMMFLVSLTNSVGGFEKLAPDSSLNDGLFDFIIVKKTNLAEFIRLVTLAARGEHINDPHVIYTKANRVKVRSSMQLNLDGEFGGMLPGEFVNLYRHLEVFMPKEKAAQVRTGP
>NC_009328.1|WP_008881411.1|335932_337453_+|flotillin-family-protein
MTVAPWLIVVGVVVLLLIGLIAIFIARYRTVGPDEALIVTGSYLGNKNVHVDESGNKIKIVRGGGTFVVPIFQQAEPLSLLSIKLDVQTPEVYTEQGVPVMADGVALIKVGSSIGEIATAAEQFLGKTRQDMENEAREVLEGHLRSILGSMTVEEIYKNRDKFSQEVQRVASQDLAKMGLVIVSFTIKDVRDKNGYLDALGKPRIAQVKRDADIATAEAEKETRIKRAEADKEARKAELERMTEIAEAEKINQLKLAEFRQEQDIAKARADQAYHLEEAKAKQEVMAQQMQIKIIERQKQIELEEKEILRRERQYDSEVKKKADAERYAIEQKAAAEKAKQIAEADAQKYRVETLAKAEAERIRLDGLAKAEAEKAKGEAEAEIIRLKGLAEAEAKQKIAEAFERYGQAAVLDMIIKMLPEYAKQVASPLSNIEKLTIVDTGSGAGGGANRVTGYATNLMASLQETLKASTGIDVKQLLENIAQGGTPASPVNPPTASGQQTNTNE
>NC_009328.1|WP_008881412.1|335374_335911_+|NfeD-family-protein
MFGYPPEVVYGAVLVVSALLTVLYFFFSDVLDGLFDVAAHPLFSPQLVLSFFIVASAVGLLAEWYTDWASHWIIWLSVGVALIVVLLLHFFVFLPLRSAEASLGYTDAELEGSLAKVIVSVPPDGFGEILISRKSGAVAKAAKSMNNEAIPSGEEVIIVRMENGIAVVARHDPYQLSI
>NC_009328.1|WP_008881413.1|332838_334557_-|M48-family-metalloprotease
MPDVTISIWTAVVGFFLSFLAYFFKKWCPSLYVYILTAILGIGWIVYVFLDQGFIKTVPIFFIFVFSFFSSPVPERSKVQLQEIIDQLKEQGAREIVLSKNKERLLVDFLFSGLFIVIAVLYFLFGPDSPITLILLYSFVSLVVGLTKRVELFRALRLFYAEHEEVLYAVSLFETKKYPLEELSEVSVQTRPDVLQLFQLFSLFSPNMDYTTSMGKTWKLSFSGEKVYFTPDPSESMAFLLKEEIHKMEEVEVKPFYHQNNWKRLLGKWYFAATVKGVGAYAALITLFTLMGIGPIVTTIVMVLFWIFNLWISDRVLKIALDMKKIDDPDLLPIIEKVFSRAGLSHVDIYVTESAEYNGFAIGANIGRSLVALTSETLKLPHEAIEGILAHEAIHVKKRDVLMGQLLRFLLIGLVLAGVFLFYKDFQNWLEHAQIFVFLSLWLLIFLLPAFQSLFTQWMEVRADHLGATLLDGGNAQMANSLTILCEYQDRALEKSAGYYVTFEKEQEANKKDKKISSLERDSWFFRFLEFQFMSHPPMYWRVHSLQTTETGWSIGKIKLWWCSRFRESLPN
>NC_009328.1|WP_008881400.1|348393_348717_+|PadR-family-transcriptional-regulator
MNTQFKKGVLELCVLALLNKQDRYGYEIVQKISEQMVISEGSVYPLLRRLKKEDYLTTYLQESNEGPPRKYYKLTEKGRNHLRNLHEEWMQFSEGVNQIIKDGGLHE
>NC_009328.1|WP_008881399.1|348709_349270_+|DUF1700-domain-containing-protein
MNKQQFLTALETELKKLPHEEREEIIQDFEEHFYIGMANGKSEEEISQSLGSPKQIAKEIAAVSRIEKIEASATVGNVLRAVWAVIGLGFFNFVTVFGPFLALLAVVFVGWFIGVAFIASPLILLVSAINHPGMFDLFSLFFSIMLCGSGWFIVRGMLYVTKVLTDLLVRYLRYNVSLVKGGLKHD
>NC_009328.1|WP_008881398.1|349262_350066_+|DUF4097-family-beta-strand-repeat-protein
MINTRHISFLALILLVVGAIGSFITFKPASKPFSVSEERILTDKTITDIEIRANDENVNIFSTKDSKTKVQLTGTSVEKMDHYFSVEVEDGTLLIKLKDDKPFFDFFHFRGTSLTLDVYLPEKVYESLHVDMNNGEIQAEKLRINNIEAKLANGYLEMKDIVATMLKADSDNGEIHLENIEGEIYGNVNNGQIYLKTNHLDRSLTLESDNGDIEIKTDQKPTNAVLDIKTKNGEVTVFGNSNWDTVIGNGENQIKLTTNNGDIRIVK
>NC_009328.1|WP_008881397.1|350441_351275_+|nucleotidyltransferase-domain-containing-protein
MVNHMIQSVAEKLSCLPFIEGVVLGGSRARGTHEEDSDIDIGIYYNAELFDLNAMNQVAAELDDERRSNLVFPPGAWGKWVNGGGWLVINGYHVDFILRDIKRVEQIIKETEQGMVTADYQTGHPHGYISAMYRGELAISKILYAKDETFCQLKKRAETYPAALRKSLIDFFMFEAEFSLLFVKKNVKANDKYYIVGHVFRMISCLNQVIFACNHAYCINEKKAIKLIETFEHKPENYAQKVNRIFELLGSSLMECCDMTEKLYNEVKQLVSEINHF
>NC_009328.1|WP_011886722.1|351394_351985_+|GrpB-family-protein
MMRSENRFTPRSDEELQKLTVGELKPHNAPITLVEYDPRWPELFEREAKRIRSVLGSKALQIEHVGSTSVPGLCAKPIIDMLLVVEDSADEPSYVPALEAAGYRLRIREPEWFEHRLFKGPDTDINLHVFSKGTSEIDKMLRFRDWLRSNESDRDKYAQVKRSLAKNKWRHVQHYADAKTSIVQEILARTNDSNAK
>NC_009328.1|WP_008878914.1|353720_354911_+|ISL3-family-transposase
MLSISLGLPEFKVIKHELLSYGYAIHVEKTETQERCPHCGFATSSVHDRRTRKVRDLAIFHQPVYLFVKVKRYRCWNCSQVFSASLESIPPNQHYTNRFCEYLYELCEGSTIQEVSRKHRIPYTTLERIYYSIASKKAKERQTATEVSSPEGMVLSLDEIAVKKGHQYETVLMDARAGSVMGMHADRQCDSAINLLSQNGLSKEMVQTVILDMWEPYHKAVRALFPSASIVIDKYHVVQKVTQALDQARKEFSPLKKARYLLLKGCEKLRKDQRLRLDDILEEYPVLSIAYYLKELFRDFYRTDGYNEAKERLEEWIKLAKQSPFASFQEAANTLERWKEPILSYFLCPYTNARIEGTNHKIKNIKRRAYGYRNLERFRLRVFLECTGNTTGSQAA
>NC_009328.1|WP_011886725.1|355960_357430_+|alanine:cation-symporter-family-protein
MIEKFVETVNGLLWSPLLIVFIVFCGLYFSIRTRFLQIRHFKEMVKLVTTGKGSDVGVSSFQALTMSLSGRIGVGNVAGTATGIAYGGPGAVFWMWVITFIGAATAYVESTLAQIYKEEQDGQYRGGPAFYIEKGLGWKWFAIVIAVAILLAMAVLMPGIQANSIADSVYNAFGINKLVTGIIVISILGFTIFGGVKRIARTAEIVVPFMAAGYLLIAIAIIGVNFDKIPEVFALIFKSAFGAEQVFGGIIGSAVMWGVKRGLYANEAGQGTGAHPAAAAEVSHPAKQGLVQAFSIYLDVFLVVTATALMILFTNQYNVINEKTGEPIVVNLEGVEPGAGYTQAAVDTLLPGFGSAFIAIALFFFAFTTMYAYYYIAETNLAYLVRGKNKGIAFLGLKIIFLAATFYGTVKTATTAWAMGDIGLGIMVWLNLIAILLLFKPAYIALKDYEEQLKQGKDPEFNSSKYEIKNATFWENGYKKSEENQKKAL
>NC_009328.1|WP_011886726.1|357624_357804_+|hypothetical-protein
MNVTNVSISSVILFLFVVSVILFVYGFVRKRKAVKWMALCFFSASIGLAVFVILLMRYM
>NC_009328.1|WP_008881301.1|358299_359532_-|serine/threonine-transporter-SstT
MKQLIAKWNRVSLVKRIIIGIIIGITLAVTVPESTKWISIFGSLFVGALKAVAPVLVFFLVISAISRHQSGQKTNIQHILILYGFSTFLASLTAVVASFLFPVHLSLTESAKEVSPPSNITEVIQSLLFNIVDNPVHALLNANYIGILTWAVLLGIALRTAPETTKNVIAHFSDAISQIVTWVINFAPIGIMGLVFDAIVTNGLSALIDYGKLLAVLLGTMCFVAFVMNPLIVFLNIRQNPYPLVWRCIRESGVTAFFTRSSAANIPVNLRLSEMLGLNKNTYSISIPLGATINMAGAAVTISVLTLAAVHTLEIEVDLGTALILSVLSAIAAAGASGVAGGSLLLIPLACSLFGIPNDIAMQVVGVGFIIGVLQDSCETALNSSSDVLFTATAEYAKRRKEGKQVAIKA
>NC_009328.1|WP_011886727.1|359806_361198_+|23S-rRNA-(uracil(1939)-C(5))-methyltransferase-RlmD
MIDGAKQSFITDIEQLDKKGAGQAVVWQEEEGKRKKLKLTIPSTLPGEKVRVLIDRPKRRKANARLEEVIEAHPERLEPPCPHFDRCGGCVWQHWQYEGQLRHKTEHVKALLEQHGFDPNIVRETIGMEHPWHYRNKMEFTFSPEGLLGLHEQGNFRQIISLETCLIAGERIVKAAMEVARWARDHQLPGYHKDTHEGLLRHVMVRESFATGEVMVALFATEAPEGELKQAADDLTERITKALPEVKSLLWLENRAWADRIQAEQTHVLAGRDFIYDELCGFRYRLWFDTFFQTNPVQAAKLVELALEMGKPQPHEKMIDLFCGVGTFSLPFAKRVKALAGIEIVETSIESAKRNAKDNGIDNTYFLARDARRGIDEVLEQFGRPELLLLDPPRSGAGGKVMRKIGRSQPERIVYVSCNPETFAADIAELVPFGYTLKTVQPVDMFPHTAHVELVALMSRVDK

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Crispr_ID: NC_009328_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009328_4

2094403-2094589

Unclear

Consensus_repeat	Method
GTGTTTCAATCCTCTAAACGAGGCCTATCTCTTTCAAC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_009328_4

>merge|NC_009328|4|2094403-2094589|CRISPRCasFinder
GATGTTCCAATCCCCTAGCGAGGCCTTTCTCTTTCAACAAAAGCAAGAGTATTAAAACCAGGCGCATTTTTGGTGGTGTTTCAATCCTCTAAACGAGGCCTATCTCTTTCAACGTCAGAGGCTCGAATGGCGCTGAAACGTCATTCAACGTGTTTCAATCCTCTAAACGAGGCCTATCTCTTTCAAC

>NC_009328|4|4|2094403-2094589|CRISPRCasFinder
GATGTTCCAATCCCCTAGCGAGGCCTTTCTCTTTCAAC	AAAAGCAAGAGTATTAAAACCAGGCGCATTTTTGGTG
GTGTTTCAATCCTCTAAACGAGGCCTATCTCTTTCAAC	GTCAGAGGCTCGAATGGCGCTGAAACGTCATTCAAC
GTGTTTCAATCCTCTAAACGAGGCCTATCTCTTTCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_009328.1\|WP_011887619.1\|2099112_2100249_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293810
NC_009328.1\|WP_008880560.1\|2090559_2090994_-\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_008880557.1\|2092827_2093094_+\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_029761633.1\|2102122_2102350_-\|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl\|CDD\|238180
NC_009328.1\|WP_008880545.1\|2101591_2102074_-\|DsrE/DsrF/DrsH-like-family-protein	unknown	unknown	gnl\|CDD\|379334
NC_009328.1\|WP_011887614.1\|2093227_2093785_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NC_009328.1\|WP_008880561.1\|2089613_2090084_+\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_008880566.1\|2085749_2086469_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226663
NC_009328.1\|WP_008880543.1\|2102453_2102714_-\|metal-sensitive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197390
NC_009328.1\|WP_008880550.1\|2098246_2099029_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NC_009328.1\|WP_008880546.1\|2101200_2101566_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089
NC_009328.1\|WP_008880548.1\|2100298_2100868_-\|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl\|CDD\|238089
NC_009328.1\|WP_008880555.1\|2094830_2095679_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|369792
NC_009328.1\|WP_011887613.1\|2091756_2092164_+\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_008880558.1\|2092184_2092589_+\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_011887617.1\|2096505_2097624_+\|acyl-CoA-desaturase	unknown	unknown	gnl\|CDD\|239583
NC_009328.1\|WP_008880562.1\|2088892_2089333_-\|hypothetical-protein	unknown	unknown	unknown
NC_009328.1\|WP_008880563.1\|2088299_2088806_+\|beta-propeller-fold-lactonase-family-protein	unknown	unknown	gnl\|CDD\|274824
NC_009328.1\|WP_008880565.1\|2086469_2087213_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226663
NC_009328.1\|WP_008880547.1\|2100891_2101188_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|238089

Protein	Function_ID	Function_description	E-value
NC_009328.1\|WP_011887619.1\|2099112_2100249_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293810	cd07724, POD-like_MBL-fold, ETHE1 (PDO type I), persulfide dioxygenase A (PDOA, PDO type II) and related proteins; MBL-fold metallo-hydrolase domain. Persulfide dioxygenase (PDO, also known as sulfur dioxygenase, SDO, EC 1.13.11.18) is a non-heme iron-dependent oxygenase which catalyzes the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria. Mutations in ethe1 (the human PDO gene) are responsible for a rare autosomal recessive metabolic disorder called ethylmalonic encephalopathy. Arabidopsis thaliana ETHE1 is essential for embryo and endosperm development. Bacterial ETHE1-type PDOs are also called Type 1 PDOs. Type II PDOs (also called PDOAs), are mainly proteobacterial. These enzymes belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.51771e-71
NC_009328.1\|WP_008880545.1\|2101591_2102074_-\|DsrE/DsrF/DrsH-like-family-protein	gnl\|CDD\|379334	pfam13686, DrsE_2, DsrE/DsrF/DrsH-like family. DsrE is a small soluble protein involved in intracellular sulfur reduction. The family also includes YrkE proteins.	2.50665e-79
NC_009328.1\|WP_008880543.1\|2102453_2102714_-\|metal-sensitive-transcriptional-regulator	gnl\|CDD\|197390	cd10155, BsYrkD-like_DUF156, Uncharacterized protein YrkD from Bacillus subtilis and related domains; this domain superfamily was previously known as part of DUF156. This domain family contains an uncharacterized protein YrkD from Bacillus subtilis and related proteins. This family is part of a larger superfamily that contains various transcriptional regulators that respond to different stressors such as Cu(I), Ni(I), sulfite, and formaldehyde, and includes CsoRs (copper-sensitive operon repressors). CsoRs form homotetramers (dimer of dimers). In Mycobacterium tuberculosis CsoR, within each dimer, two Cys residues on opposite subunits, along with a His residue, bind the Cu(I) ion (forming a triagonal S2N coordination complex, C-H-C). These residues are conserved in the majority of members of this superfamily. In this family, however, not all these residues are conserved, there is an Asn instead of the His (C-N-C); also a conserved Tyr and a Glu residue that facilitates allosteric regulation of DNA binding for CsoRs are very poorly conserved.	6.86231e-36
NC_009328.1\|WP_029761633.1\|2102122_2102350_-\|sulfurtransferase-TusA-family-protein	gnl\|CDD\|238180	cd00291, SirA_YedF_YeeD, SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.	2.22989e-30
NC_009328.1\|WP_008880546.1\|2101200_2101566_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	2.61715e-34
NC_009328.1\|WP_008880566.1\|2085749_2086469_+\|ABC-transporter-permease	gnl\|CDD\|226663	COG4200, COG4200, Uncharacterized protein conserved in bacteria [Function unknown].	1.50794e-31
NC_009328.1\|WP_008880550.1\|2098246_2099029_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.38001e-30
NC_009328.1\|WP_011887614.1\|2093227_2093785_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	4.51068e-59
NC_009328.1\|WP_008880548.1\|2100298_2100868_-\|sulfurtransferase-TusA-family-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	7.2878e-34
NC_009328.1\|WP_008880555.1\|2094830_2095679_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	1.89252e-73
NC_009328.1\|WP_008880563.1\|2088299_2088806_+\|beta-propeller-fold-lactonase-family-protein	gnl\|CDD\|274824	TIGR03866, PQQ_ABC_repeats, PQQ-dependent catabolism-associated beta-propeller protein. Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.	5.63813e-30
NC_009328.1\|WP_011887617.1\|2096505_2097624_+\|acyl-CoA-desaturase	gnl\|CDD\|239583	cd03506, Delta6-FADS-like, The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases are required for the synthesis of highly unsaturated fatty acids (HUFAs), which are mainly esterified into phospholipids and contribute to maintaining membrane fluidity. While HUFAs may be required for cold tolerance in bacteria, plants and fish, the primary role of HUFAs in mammals is cell signaling. These enzymes are described as front-end desaturases because they introduce a double bond between the pre-exiting double bond and the carboxyl (front) end of the fatty acid. Various substrates are involved, with both acyl-coenzyme A (CoA) and acyl-lipid desaturases present in this CD. Acyl-lipid desaturases are localized in the membranes of cyanobacterial thylakoid, plant endoplasmic reticulum (ER), and plastid; and acyl-CoA desaturases are present in ER membrane. ER-bound plant acyl-lipid desaturases and acyl-CoA desaturases require cytochrome b5 as an electron donor. Most of the eukaryotic desaturase domains have an adjacent N-terminal cytochrome b5-like domain. This domain family has extensive hydrophobic regions that would be capable of spanning the membrane bilayer at least twice. Comparison of sequences also reveals the existence of three regions of conserved histidine cluster motifs that contain the residues: HXXXH, HXX(X)HH, and Q/HXXHH. These histidine residues are reported to be catalytically essential and proposed to be the ligands for the iron atoms contained within the homolog, stearoyl CoA desaturase.	2.26896e-38
NC_009328.1\|WP_008880565.1\|2086469_2087213_+\|ABC-transporter-permease	gnl\|CDD\|226663	COG4200, COG4200, Uncharacterized protein conserved in bacteria [Function unknown].	6.93363e-32
NC_009328.1\|WP_008880547.1\|2100891_2101188_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|238089	cd00158, RHOD, Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins such as sulfide dehydrogenases and certain stress proteins such as senesence specific protein 1 in plants, PspE and GlpE in bacteria and cyanide and arsenate resistance proteins. Inactive versions (no active site cysteine) are also seen in dual specificity phosphatases, ubiquitin hydrolases from yeast and in sulfuryltransferases, where they are believed to play a regulatory role in multidomain proteins.	2.62678e-30

>NC_009328.1|WP_011887614.1|2093227_2093785_+|signal-peptidase-I
MGKKKSEFWGWMKTIIIAILLASSVRYFLFAPFVVEGQSMMPTLHDQDRMIVNKIKYSFVKPERFDIIVFHTKDKKDYIKRIIGLPGDRIEYKNDTLYINGKAYKEPYLDEYKKQNKSGLPLTESFTLKDTPIGRSTVPEGYLFVMGDNRRNSKDSRHIGAIPMDDVVGEANIICWPFNRIQIMK
>NC_009328.1|WP_008880557.1|2092827_2093094_+|hypothetical-protein
MKGTGALLIFPFLSSFFGYTDHMEPPVIQGQVSVSISSPTESYDQSSPIQELAPQTFGASVEKSVTLPSGLHISASSSSTVIVPEFTK
>NC_009328.1|WP_008880558.1|2092184_2092589_+|hypothetical-protein
MIMKKLVKTVGISAMLLAGSFVAGNAAPASAAGLGDVLGAVNSLVGETNVSSGSVVSATGPNFEIQAGSTYTNNQNGVTGLVGGVLGGTYNTNASLSGPNGLSASASTSGSYGLASSVQSLTNGLGGLLGGLLK
>NC_009328.1|WP_011887613.1|2091756_2092164_+|hypothetical-protein
MKKLILSAGLSTAILMGGMGSAFAAEQPSNAPDGGLGSVLGAVNQLIGSTKVEVQSGASLKVDGVTVTAQAVNSTEQSGLTGLLSGGVLGGTSGTSASVSYAGYSASTSASGSWGLASSVQSIGGLLNSLGQSLK
>NC_009328.1|WP_008880560.1|2090559_2090994_-|hypothetical-protein
MLKKLAAFLAVFVMAFGVFFTSQAYAYTQFGPASWRTEDGKYELTLKTTSTDNDVTVVIWDLYRVSYSTGKAVPYWTEELKVRLCNASTGNCTSFKNLTDPLGHSAFGADFTNMKPGTFYVDIRDPDPGYYYKGLIRATVQNVY
>NC_009328.1|WP_008880561.1|2089613_2090084_+|hypothetical-protein
MIKGLKKGIVALITAGALVFVLGNPNTYAASYTDFGPASFATEDGKYELTIRTTSVEKNVTIWVYDLYRVNRNSGAVTSMNGDTSPLSVRLCNASTGNCTAFKSFWEGNSSAIFTNMKAGTFYVDIRDSWANYYFKGKVAAKTYSWNPDDCWLDCN
>NC_009328.1|WP_008880562.1|2088892_2089333_-|hypothetical-protein
MKKILLFSLIVLFSLMSFHPDVYAATLKDKSTIIFDGAPDGKVYTTRKVKVPKGGYLGVYGYNNNSDLGHTWLYFRVYRDDGKDVTNQFWQKDPVWGYFLNEEEIVNKRVGPINEEHSYYIWAQCEFRWAPIGTGCDGTFSISSWY
>NC_009328.1|WP_008880563.1|2088299_2088806_+|beta-propeller-fold-lactonase-family-protein
MSKCQNDNQVIRIRCGCTNLRTVTVHRPISPEPGGPDGPGPSIFAYVTNAADNTVSVIDTSTNAVIATIPVGFAPYSATITPDGTRAYVANANDNTISVIDTSTNTVIATIPVASPHDIDLTPDGTHAYVTNTTTNTVSVLNTATNTVITTIPVGNAPHGIAITPVAI
>NC_009328.1|WP_008880565.1|2086469_2087213_+|ABC-transporter-permease
MISLLQSEWFKLRKSKFVFTAILLGPLITFFYALMLQPDTFGLEKRFLWEFLIAFTTLLYALRFLPLTTGILAGLICRYEHQNGGWKQLLALPVTRSRVFLAKYTILMLITLTIQLLYLLAIWTSGVLKGAEEPFPMMLLWKSIFGGWIATLPLLALQLWMSMLFKSFAAPFAVNVVFTLPAILAVNSEKFGPLYPWAQPFLMMYVSGDAENDIFFVPWEQVLTVIGGSFLIFFFGGLLYFRRKENI
>NC_009328.1|WP_008880566.1|2085749_2086469_+|ABC-transporter-permease
MIMKLLATDFLKIKRKGLWFLTILGPLGVVLLQWVNYELVPGRREWLLQRSDDDWLFYLQNVNSFTPLALVLGITILTSLAASIENETNAWKQLIALPISKMGVFLSKFTVLAFLLAIASVLLFFFTWLLGIYLDLGAVIPYAQIATFSFYPYFASLPLLALHLWVATVSNNQGIPISLGVIGFLFTSYSFKLPDWLPWKWPSLQNQWDEPLVNVVLGICVGIILYIIGMLDFARRDVK
>NC_009328.1|WP_008880555.1|2094830_2095679_-|Cof-type-HAD-IIB-family-hydrolase
MLIALDMDGTLLNGEGKISEQNRKAIMAAQAQGHLVAVVTGRARKDALAPLREAGLVCPIASLNGAIVTLEDGTVISQAPLERTVIRHALDWVREQSDLYCETYVGDEVYVGLHNRAQWEALALEKTEVAPEVKWIVMKQFQQARVTYVDDIRTVWDDPKRVIYKLLIFSLDRERLRDAASHFDPLPGVTVTSSHPHNIEVNNERATKGEALKQLASHYGIDLRDTVVFGDSHNDLSMFEVAGCRVAMANAAPELKSTCDFVTLSHEEDGVAAGLEQVLVRR
>NC_009328.1|WP_011887617.1|2096505_2097624_+|acyl-CoA-desaturase
MNDFHPFGWYAAKIAPHLPKKAFQPVKSRLFGGLAYFLLVTGGILAVSLLSLHPIWNLLISVVLGFSFAALGFLGHEILHGTVVKTPWLRDLLGAIAFWPLCTGPKLWRKWHNATHHVHTQHEEKDPDAWPSMEQLVKSRLLRWVYRIPFPIRAFFAFSSLSVMFTVHSIRMLFSFFRDFRWKNRTVVLLQFFLPWTTWLGLLWLIGWEKWWFAFLLPLLIANMIVMGYISTNHRLNPLVPVNDPLANSLSVTVPKWVDVLHFNFSYHTEHHLFPAMSSKYYPLVKEHIKQMWPDRYHEMPMKKALAALWKTPRIYYEHSELIEPKQGHVYGTLGNGLDPNEIVHRELKQDAQALPTMRQEEWKKASGVEKV
>NC_009328.1|WP_008880550.1|2098246_2099029_-|sulfite-exporter-TauE/SafE-family-protein
MDLSLQLIIVIFLIGFIGSFISGMVGIGGSIIKYPMLLYLPPLFGLAAFSAHEVSGISAVQVFFATIGGVWAYRKGGYLNKSLILYMGASILIGSFVGGYGSKLMSEGAMNVVYGVLAALAAIMMFVPKKGIDDIPLDQVTFNKWLAAVLAFLIGVGSGIVGAAGAFLLVPIMLVVLKIPTRMTIATSLAVTFISSIGSTFGKITTGQVDYIPALVMVAASLLASPLGAKTGQKMNTKVLQVILAVLVLATAVNIWVDIL
>NC_009328.1|WP_011887619.1|2099112_2100249_-|MBL-fold-metallo-hydrolase
MMKEMTVQQMTEKVLNKESLFILDVRNESDFRDWKIEGENFAYLNVPYFELVHGVDSIVDRLPKDQDIVVVCAKGGSAAFVAEQLAEAGFDNVYTLAGGMQAWSEHLHQAKVYEDDQLKIYQFIRVGKGCLSYMVLSGDEALVVDPLRFIDVYEQVAQQEGVTITHIVDSHLHADHLSGGKALAERTGAAYYLMKSEGAVFDFEPLEQHETIDFENVHLEVLAVKTPGHTPGSVSFFVNGKWLFSGDTIFVGGLGRPDLGGKVAEWAEDLYHTVYEKVAAMADDVIVLPAHYANLDEEINAEGYVGDTLGRIRARNEMMQNKAKDEFIDLVIQGAKTETPPNFEDIVAINRGLKTVDIETQRELEIGPNRCALHHTHA
>NC_009328.1|WP_008880548.1|2100298_2100868_-|sulfurtransferase-TusA-family-protein
MIKVDMIVDAKGLSCPMPIVRTKKAIGELQSGQVLEVQATDKGSKADMKAWAESTGHQYLGTIEEDGVLKHYIRKSAEHETRNEVTFPHVVSNEQLQEKFHDPDSFVLDVREPAEYAFGHIPGAVSIPLGDLDSRMAELPKDKTIYVVCRTGTRSDLAAQKLAENGFDRVRNVIPGMSQWNGPLDSAQS
>NC_009328.1|WP_008880547.1|2100891_2101188_-|rhodanese-like-domain-containing-protein
MKTITPKEVEERLRAGESLRIIDVREPDEVAAGKIPGAVNIPLGLIEFRMHELDKKKEYILVCRSGGRSGRAGEFLDSRGYRVVNMTGGMLAWEGPVE
>NC_009328.1|WP_008880546.1|2101200_2101566_-|rhodanese-like-domain-containing-protein
MVQTVINIILFALLAWFLASRFIPPKGVQMITTAELKRRLKQSGVQYIDVRTPMEFRSFHLPGFRNIPLHELAARARELSKEKEVVVICQSGMRSQKASKWLKKMGFQHVTNVKGGLNAWQ
>NC_009328.1|WP_008880545.1|2101591_2102074_-|DsrE/DsrF/DrsH-like-family-protein
MTQLKKKTTIILFSGDYDKAMAAYIIANGAAAYDHDVTIFHTFWGLNALRKEAPVPVQKGFLEKMFAKMMPRGADRMGLSRMNFAGIGPKLIKKVIKKHNAMPLPQLIEMAKEQGVKLVACQMTVDLLGLKPEELIDGIEFAGVAAYLADASEGNVNLFI
>NC_009328.1|WP_029761633.1|2102122_2102350_-|sulfurtransferase-TusA-family-protein
MNVAKVLDAKGLACPMPVVRAKKAMDELQSGQVLEVHTTDKGAKNDLPAWAKASGHTVIDMKEENGVLMFWIQKG
>NC_009328.1|WP_008880543.1|2102453_2102714_-|metal-sensitive-transcriptional-regulator
MEYNKEIKNRLKRIEGQIKGVLGMMEQGKDCKSVVSQLSAARNAIDRAIAVIVSTNLEHCLRESMEKGETTDHLVKEAVELLVKSR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

266758 : 275148

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008881467.1\|266758_268054_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	1.7e-18	24.3
WP_029761594.1\|268130_268859_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3FUQ7	Synechococcus_phage	1.6e-45	42.4
WP_008881465.1\|268846_269101_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_008881464.1\|269097_269784_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_008881463.1\|269767_271996_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.1e-166	41.7
WP_008881462.1\|271971_273384_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	6.4e-51	34.9
WP_011886685.1\|273481_274522_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	6.5e-69	47.0
WP_008881460.1\|274518_275148_+	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	7.8e-25	35.7

DBSCAN-SWA_2

293455 : 365963

Staphylococcus_phage(11.11%)

tRNA,transposase,protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008881445.1\|293455_293746_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_008881444.1\|293758_295216_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_008881443.1\|295229_296660_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_008881442.1\|296846_298151_+	homocysteine synthase	A0A0B5JD48	Pandoravirus	2.8e-21	26.8
WP_008881441.1\|298822_298993_+	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
WP_011886696.1\|299767_302908_+	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	4.4e-92	26.4
WP_008881438.1\|303074_304904_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	1.1e-18	30.2
WP_011886697.1\|304872_306180_+	lanthionine synthetase C family protein	NA	NA	NA	NA
WP_008881436.1\|306522_307221_+	response regulator transcription factor	NA	NA	NA	NA
WP_011886698.1\|307207_308626_+	HAMP domain-containing histidine kinase	Q6XM27	Feldmannia_irregularis_virus	1.3e-06	23.1
WP_011886699.1\|308719_309154_-	NisI/SpaI family lantibiotic immunity lipoprotein	NA	NA	NA	NA
WP_041264183.1\|309208_309997_-	lantibiotic immunity ABC transporter MutG family permease subunit	NA	NA	NA	NA
WP_011886701.1\|309998_310745_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	NA	NA	NA	NA
WP_011886702.1\|310763_311453_-	lantibiotic protection ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	6.7e-54	47.5
WP_011886703.1\|312107_312737_-	ABC transporter permease	NA	NA	NA	NA
WP_011886704.1\|313126_314260_-\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.4e-29	35.5
WP_008881427.1\|314276_315179_-	glycine/betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_148206523.1\|315431_315611_+	hypothetical protein	NA	NA	NA	NA
WP_011886706.1\|316171_316918_+	CRISPR-associated endoribonuclease Cas6	NA	NA	NA	NA
WP_011886707.1\|318004_318448_+	ASCH domain-containing protein	NA	NA	NA	NA
WP_008881425.1\|318800_320039_-	MFS transporter	NA	NA	NA	NA
WP_011886708.1\|320211_320865_-	PspA/IM30 family protein	NA	NA	NA	NA
WP_008881423.1\|320824_321346_-	hypothetical protein	NA	NA	NA	NA
WP_008881422.1\|321515_322889_-	GHKL domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	6.7e-13	26.4
WP_011886711.1\|322878_323541_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.0e-31	34.7
WP_008881420.1\|323904_325113_+	trypsin-like peptidase domain-containing protein	W5SAB9	Pithovirus	2.6e-13	30.7
WP_171355685.1\|325871_326159_+	DUF997 family protein	NA	NA	NA	NA
WP_008881418.1\|326155_327625_+	sodium/panthothenate symporter	NA	NA	NA	NA
WP_011886713.1\|327628_328858_+	M20 family metallopeptidase	NA	NA	NA	NA
WP_008881416.1\|328861_329935_+	tartrate dehydrogenase	NA	NA	NA	NA
WP_011886714.1\|329961_330708_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_008881414.1\|331082_332528_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_008881413.1\|332838_334557_-\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_008881412.1\|335374_335911_+	NfeD family protein	NA	NA	NA	NA
WP_008881411.1\|335932_337453_+	flotillin family protein	A0A2I2L4B2	Orpheovirus	4.7e-07	27.6
WP_008881410.1\|337597_338518_+	diacylglycerol kinase	A0A1V0SBJ0	Catovirus	2.3e-25	30.9
WP_008881409.1\|338592_339975_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	3.6e-123	48.4
WP_011886717.1\|340643_342029_-	L-cystine transporter	NA	NA	NA	NA
WP_011886718.1\|342367_343141_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.7e-27	36.1
WP_011886719.1\|343115_344987_+	ABC transporter permease	NA	NA	NA	NA
WP_011886720.1\|345011_345368_+	YxeA family protein	NA	NA	NA	NA
WP_008881404.1\|345768_346119_+	DUF2200 domain-containing protein	NA	NA	NA	NA
WP_008881400.1\|348393_348717_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_008881399.1\|348709_349270_+	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_008881398.1\|349262_350066_+	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_008881397.1\|350441_351275_+	nucleotidyltransferase domain-containing protein	A0A1X9I6C9	Streptococcus_phage	2.0e-129	78.0
WP_011886722.1\|351394_351985_+	GrpB family protein	NA	NA	NA	NA
WP_008878914.1\|353720_354911_+\|transposase	ISL3 family transposase	A0A0A8WEF4	Clostridium_phage	6.8e-30	25.4
WP_011886725.1\|355960_357430_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_011886726.1\|357624_357804_+	hypothetical protein	NA	NA	NA	NA
WP_008881301.1\|358299_359532_-	serine/threonine transporter SstT	NA	NA	NA	NA
WP_011886727.1\|359806_361198_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	F5CA72	Streptococcus_phi-m46.1-like_phage	1.1e-50	30.7
WP_011886728.1\|361434_361845_+\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	2.5e-40	57.0
WP_008881273.1\|362636_363419_-	helix-turn-helix transcriptional regulator	D2XQ11	Bacillus_virus	9.1e-07	35.7
WP_011886641.1\|363592_364483_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_011886729.1\|364796_365963_-\|transposase	IS256 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

793626 : 830793

Tupanvirus(20.0%)

transposase,integrase,coat

attL 814568:814582|attR 839563:839577

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011886952.1\|793626_794676_-\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_008878951.1\|794904_796044_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_011886953.1\|796049_797069_+\|coat	CotS family spore coat protein	NA	NA	NA	NA
WP_008878949.1\|797078_797696_+	hypothetical protein	NA	NA	NA	NA
WP_011886954.1\|797770_798934_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_008878947.1\|798930_799887_-	NAD-dependent epimerase/dehydratase family protein	A0A2K9L4U8	Tupanvirus	7.1e-38	33.6
WP_008878946.1\|799883_801167_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.4e-73	36.9
WP_011886956.1\|801840_802176_-	hypothetical protein	NA	NA	NA	NA
WP_029761542.1\|802345_802696_+	DUF1360 domain-containing protein	NA	NA	NA	NA
WP_008878943.1\|802883_803648_-	hypothetical protein	NA	NA	NA	NA
WP_008878942.1\|803750_804473_-	hypothetical protein	NA	NA	NA	NA
WP_008878941.1\|804623_804962_+\|coat	spore coat protein	NA	NA	NA	NA
WP_008878940.1\|805233_805458_+	hypothetical protein	NA	NA	NA	NA
WP_008878939.1\|805485_805689_+	hypothetical protein	NA	NA	NA	NA
WP_008878938.1\|805852_806059_+	DUF1657 domain-containing protein	NA	NA	NA	NA
WP_011886959.1\|806155_806632_+	YhcN/YlaJ family sporulation lipoprotein	NA	NA	NA	NA
WP_008878936.1\|806643_807123_+	stage V sporulation protein AC	NA	NA	NA	NA
WP_041264264.1\|807122_808136_+	stage V sporulation protein AD	NA	NA	NA	NA
WP_008878934.1\|808137_808494_+	stage V sporulation protein AE	NA	NA	NA	NA
WP_008878933.1\|808505_808712_+	DUF1657 domain-containing protein	NA	NA	NA	NA
WP_008878932.1\|808724_809585_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_008878931.1\|809604_809775_+	hypothetical protein	NA	NA	NA	NA
WP_008878930.1\|809900_810221_-	thioredoxin family protein	NA	NA	NA	NA
WP_008878929.1\|810345_810582_+	hypothetical protein	NA	NA	NA	NA
WP_008878928.1\|810659_810794_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_008878927.1\|810918_811176_+	stage VI sporulation protein F	NA	NA	NA	NA
WP_008878926.1\|811210_811645_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_008878925.1\|811644_812166_-	YjcG family protein	NA	NA	NA	NA
WP_008878924.1\|812204_812933_-	esterase family protein	NA	NA	NA	NA
WP_008878923.1\|813422_814526_+	methionine biosynthesis PLP-dependent protein	A0A0B5JD48	Pandoravirus	4.7e-17	27.1
WP_008878922.1\|814529_815708_+	cystathionine beta-lyase	NA	NA	NA	NA
814568:814582	attL	NA	NA	NA	NA
WP_008878921.1\|815810_816020_-	hypothetical protein	NA	NA	NA	NA
WP_008878920.1\|816036_816468_-	hypothetical protein	NA	NA	NA	NA
WP_008878919.1\|816734_817433_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_011886967.1\|817435_818557_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_011886968.1\|818553_819609_+	polysaccharide pyruvyl transferase family protein	NA	NA	NA	NA
WP_011886969.1\|819932_821096_-\|integrase	site-specific integrase	S5MNZ2	Brevibacillus_phage	7.2e-93	46.7
WP_011886970.1\|821148_821979_-	hypothetical protein	NA	NA	NA	NA
WP_041264267.1\|822128_822323_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011886971.1\|822657_823632_+	hypothetical protein	NA	NA	NA	NA
WP_011886972.1\|823675_824359_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_087959838.1\|824495_825664_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.4e-59	42.8
WP_041264804.1\|826405_827233_+	hypothetical protein	NA	NA	NA	NA
WP_041264270.1\|829778_829973_+	zinc finger protein	NA	NA	NA	NA
WP_167526072.1\|830568_830793_+\|transposase	transposase	NA	NA	NA	NA
839563:839577	attR	NA	NA	NA	NA

DBSCAN-SWA_4

862888 : 872720

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011886997.1\|862888_864796_+	asparagine synthase (glutamine-hydrolyzing)	A0A1V0SGM7	Hokovirus	4.6e-36	31.0
WP_011886998.1\|865014_866079_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	2.0e-89	50.6
WP_041264281.1\|866075_866750_-	response regulator transcription factor	W8CYM9	Bacillus_phage	8.5e-78	64.4
WP_011887000.1\|866980_867772_-	ABC transporter permease	NA	NA	NA	NA
WP_011887001.1\|867773_868784_-	ATP-binding cassette domain-containing protein	W6JKT0	Anomala_cuprea_entomopoxvirus	4.9e-21	30.1
WP_029760345.1\|869297_871580_+	ribonucleoside-diphosphate reductase subunit alpha	A0A0Y0AS84	Bacillus_phage	4.7e-306	68.5
WP_008878886.1\|871685_872720_+	ribonucleotide-diphosphate reductase subunit beta	A0A127AVZ3	Bacillus_phage	1.3e-122	61.4

DBSCAN-SWA_5

1626508 : 1680240

Staphylococcus_phage(11.11%)

transposase,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148206527.1\|1626508_1627696_+\|coat	spore coat protein CotH	NA	NA	NA	NA
WP_011887377.1\|1627817_1628486_+	hypothetical protein	NA	NA	NA	NA
WP_041264418.1\|1628593_1629943_-	arsenic transporter	A0A2H4PQU3	Staphylococcus_phage	4.5e-46	29.3
WP_011887379.1\|1630255_1630552_-	S-adenosylmethionine decarboxylase	NA	NA	NA	NA
WP_008879155.1\|1630860_1631361_+	hypothetical protein	NA	NA	NA	NA
WP_011887380.1\|1631696_1633547_-	hypothetical protein	NA	NA	NA	NA
WP_008879152.1\|1633745_1634381_+	hypothetical protein	NA	NA	NA	NA
WP_011887381.1\|1634486_1635065_+	hypothetical protein	NA	NA	NA	NA
WP_029760777.1\|1635187_1635673_-	hypothetical protein	NA	NA	NA	NA
WP_171355651.1\|1636014_1636983_+	UV DNA damage repair endonuclease UvsE	A0A1C9LW13	Vibrio_phage	8.0e-13	25.0
WP_008879147.1\|1638177_1638888_+	EAL domain-containing protein	NA	NA	NA	NA
WP_011887385.1\|1640419_1641589_+\|transposase	IS256 family transposase	NA	NA	NA	NA
WP_008879145.1\|1642000_1642237_+	hypothetical protein	NA	NA	NA	NA
WP_008879144.1\|1642322_1643060_+	response regulator transcription factor	NA	NA	NA	NA
WP_008879143.1\|1643144_1644440_+	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	2.8e-13	34.4
WP_008879140.1\|1645662_1647870_+	catalase/peroxidase HPI	NA	NA	NA	NA
WP_008879139.1\|1648266_1648692_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_011887388.1\|1648717_1648924_+	hypothetical protein	NA	NA	NA	NA
WP_008879137.1\|1649127_1650225_-	hypothetical protein	NA	NA	NA	NA
WP_008879136.1\|1650311_1650761_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_011887390.1\|1651811_1653386_+	Vga family ABC-F type ribosomal protection protein	A0A1B0RXA0	Streptococcus_phage	7.3e-72	37.7
WP_008879134.1\|1653641_1654250_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_008879133.1\|1654888_1655953_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_011887391.1\|1656356_1656746_+	hypothetical protein	NA	NA	NA	NA
WP_008879131.1\|1656774_1658238_+	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_008879130.1\|1658515_1659409_+	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_008879129.1\|1659519_1660395_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_008879128.1\|1660613_1661039_-	hypothetical protein	NA	NA	NA	NA
WP_008879127.1\|1661041_1661245_-	helix-turn-helix transcriptional regulator	A0A1V0E021	Clostridioides_phage	5.0e-10	52.5
WP_008879126.1\|1661948_1662395_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_008879125.1\|1662628_1663162_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011887393.1\|1664103_1666143_-	molybdopterin oxidoreductase family protein	A0A077SK27	Escherichia_phage	2.3e-57	27.0
WP_008879122.1\|1666594_1667227_+	YdeI/OmpD-associated family protein	NA	NA	NA	NA
WP_011887395.1\|1669967_1670555_+	AAA family ATPase	NA	NA	NA	NA
WP_008879116.1\|1671105_1671618_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_008879114.1\|1672329_1672611_+	hypothetical protein	NA	NA	NA	NA
WP_008878914.1\|1673067_1674258_-\|transposase	ISL3 family transposase	A0A0A8WEF4	Clostridium_phage	6.8e-30	25.4
WP_041264426.1\|1674869_1675253_+	hypothetical protein	NA	NA	NA	NA
WP_011887396.1\|1675814_1676291_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011887397.1\|1676435_1677059_-	LysE family translocator	NA	NA	NA	NA
WP_011887400.1\|1677957_1678248_+\|transposase	transposase	Q6J1X3	Lactobacillus_phage	7.0e-05	34.8
WP_081432642.1\|1678244_1679063_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.3e-45	43.0
WP_148206525.1\|1679011_1680240_-\|transposase	IS3 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

2146414 : 2201714

Bacillus_phage(37.5%)

transposase,integrase,protease

attL 2194930:2194945|attR 2199492:2199507

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008880494.1\|2146414_2147197_-\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_008880493.1\|2147211_2147868_-	SdpI family protein	NA	NA	NA	NA
WP_171355512.1\|2147864_2148176_-	autorepressor SdpR family transcription factor	NA	NA	NA	NA
WP_011887644.1\|2148907_2149411_-	DoxX family protein	NA	NA	NA	NA
WP_008880490.1\|2149879_2151316_-	sodium/proline symporter	NA	NA	NA	NA
WP_008880489.1\|2151599_2152841_+	aminopeptidase	NA	NA	NA	NA
WP_008880488.1\|2152946_2153264_-	hypothetical protein	NA	NA	NA	NA
WP_008880487.1\|2153444_2154215_-	3-oxoacyl-ACP reductase	NA	NA	NA	NA
WP_008880486.1\|2154227_2155259_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_008880485.1\|2155255_2156011_-	ABC transporter permease	NA	NA	NA	NA
WP_008880484.1\|2156007_2156754_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	8.6e-39	39.1
WP_008880483.1\|2156768_2158220_-	acyl-CoA reductase	NA	NA	NA	NA
WP_008880482.1\|2158216_2159332_-	long-chain-fatty-acid--CoA ligase	NA	NA	NA	NA
WP_011886641.1\|2160199_2161090_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_167526076.1\|2161253_2161961_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_008880480.1\|2161962_2162892_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_008880479.1\|2163086_2165864_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_171355773.1\|2167431_2167590_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_049756695.1\|2167543_2167993_-	hypothetical protein	S6AVV9	Thermus_phage	6.4e-13	76.8
WP_011887652.1\|2172904_2173633_-	hypothetical protein	NA	NA	NA	NA
WP_148206531.1\|2173625_2174009_-	hypothetical protein	NA	NA	NA	NA
WP_008878914.1\|2174025_2175216_+\|transposase	ISL3 family transposase	A0A0A8WEF4	Clostridium_phage	6.8e-30	25.4
WP_011887653.1\|2175364_2175985_-	hypothetical protein	NA	NA	NA	NA
WP_008881865.1\|2176141_2176438_-	hypothetical protein	NA	NA	NA	NA
WP_008881866.1\|2176543_2177827_-	hypothetical protein	NA	NA	NA	NA
WP_008881867.1\|2177810_2178653_-	DNA adenine methylase	A0A1S5PRR3	Streptococcus_phage	6.6e-80	54.0
WP_008881870.1\|2179199_2179511_-	hypothetical protein	NA	NA	NA	NA
WP_008881871.1\|2179520_2180192_-	hypothetical protein	NA	NA	NA	NA
WP_008881872.1\|2180191_2180425_-	hypothetical protein	NA	NA	NA	NA
WP_008881873.1\|2180447_2180717_-	hypothetical protein	NA	NA	NA	NA
WP_008881874.1\|2180719_2180941_-	hypothetical protein	NA	NA	NA	NA
WP_011887655.1\|2181159_2181765_-	hypothetical protein	NA	NA	NA	NA
WP_008881877.1\|2181774_2182422_-	hypothetical protein	NA	NA	NA	NA
WP_008881878.1\|2182444_2182681_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_008881879.1\|2184096_2185269_-	erythromycin esterase family protein	NA	NA	NA	NA
WP_011887656.1\|2185269_2187435_-	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	1.4e-33	28.1
WP_011887657.1\|2187464_2190545_-	type 2 lantipeptide synthetase LanM	NA	NA	NA	NA
WP_160331332.1\|2190629_2190803_-	class II lanthipeptide, LchA2/BrtA2 family	NA	NA	NA	NA
WP_008881883.1\|2190942_2191614_-	response regulator transcription factor	NA	NA	NA	NA
WP_011887658.1\|2191639_2193904_-	PDZ domain-containing protein	NA	NA	NA	NA
WP_008881885.1\|2193910_2194066_-	competence pheromone ComX	NA	NA	NA	NA
WP_008881886.1\|2194083_2195016_-	polyprenyl synthetase family protein	NA	NA	NA	NA
2194930:2194945	attL	NA	NA	NA	NA
WP_008881887.1\|2195352_2196528_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_011887659.1\|2196797_2197712_+\|integrase	tyrosine-type recombinase/integrase	A0A1B1IQT7	uncultured_Mediterranean_phage	3.4e-13	24.4
WP_011887660.1\|2197795_2198818_-	hypothetical protein	A0A1P8CWW3	Bacillus_phage	1.0e-18	29.9
WP_008881890.1\|2199126_2200380_+	DNA polymerase IV	O64031	Bacillus_phage	8.9e-113	51.1
2199492:2199507	attR	NA	NA	NA	NA
WP_081432647.1\|2200472_2200724_+	YolD-like family protein	NA	NA	NA	NA
WP_008881892.1\|2200835_2201714_-\|transposase	IS982 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

2268053 : 2278759

Pandoravirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008879611.1\|2268053_2269073_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	2.4e-68	42.2
WP_008879612.1\|2269066_2270593_-	anthranilate synthase component I	S4VNU7	Pandoravirus	9.0e-35	37.7
WP_008879613.1\|2270824_2271205_-	chorismate mutase	NA	NA	NA	NA
WP_011887695.1\|2271201_2272302_-	3-dehydroquinate synthase	E5ERI4	Ostreococcus_lucimarinus_virus	4.8e-22	28.5
WP_008879615.1\|2272304_2273471_-	chorismate synthase	A0A291AU41	Pandoravirus	3.8e-41	36.2
WP_008879616.1\|2273572_2274343_-	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
WP_008879617.1\|2274421_2274871_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	7.0e-28	46.2
WP_008879618.1\|2274968_2275931_-	heptaprenyl diphosphate synthase component II	A0A1V0SE37	Indivirus	1.1e-06	23.6
WP_029760974.1\|2275947_2276652_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_029760975.1\|2276656_2277436_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_008879621.1\|2277549_2277774_-	trp RNA-binding attenuation protein MtrB	NA	NA	NA	NA
WP_029760976.1\|2277786_2278353_-	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	4.8e-50	54.9
WP_008879623.1\|2278486_2278759_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	3.5e-30	78.9

DBSCAN-SWA_8

2338297 : 2348773

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041264543.1\|2338297_2339443_-	D-alanyl-D-alanine carboxypeptidase	B6DZZ7	Stx2-converting_phage	1.1e-21	33.6
WP_011887726.1\|2339741_2341091_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.8e-39	45.0
WP_011887727.1\|2341306_2341531_+	hypothetical protein	NA	NA	NA	NA
WP_008879698.1\|2341963_2342362_-	hypothetical protein	NA	NA	NA	NA
WP_008879699.1\|2342408_2343038_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	9.5e-15	34.9
WP_041264876.1\|2343269_2344025_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	1.9e-09	26.2
WP_011887729.1\|2344291_2344804_+	DUF309 domain-containing protein	NA	NA	NA	NA
WP_011887730.1\|2344855_2345209_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011887731.1\|2345329_2345794_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	8.8e-42	60.4
WP_041264546.1\|2345811_2347005_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.7e-118	54.1
WP_011887733.1\|2347028_2347673_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.5e-39	44.6
WP_008879706.1\|2347672_2348773_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.1e-58	38.8

DBSCAN-SWA_9

2632195 : 2689476

Pacmanvirus(20.0%)

tRNA,coat,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041264616.1\|2632195_2633812_-\|coat	SafA/ExsA family spore coat assembly protein	NA	NA	NA	NA
WP_011887898.1\|2633970_2635074_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_008881057.1\|2635088_2635919_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_011887899.1\|2635951_2637514_-	L-aspartate oxidase	NA	NA	NA	NA
WP_008881059.1\|2637618_2638764_+	IscS subfamily cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	9.5e-29	27.3
WP_011887901.1\|2638751_2639300_+	transcription repressor NadR	NA	NA	NA	NA
WP_011887902.1\|2639578_2640427_-	prephenate dehydratase	NA	NA	NA	NA
WP_008881062.1\|2640448_2640892_-	ACT domain-containing protein	NA	NA	NA	NA
WP_011887904.1\|2640909_2642211_-	GTPase ObgE	NA	NA	NA	NA
WP_008881064.1\|2642305_2642866_-	Spo0B domain-containing protein	NA	NA	NA	NA
WP_008881065.1\|2643043_2643334_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_011887906.1\|2643349_2643682_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_008881067.1\|2643685_2643994_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_029760656.1\|2644240_2645101_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_011887908.1\|2645093_2645861_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_008881070.1\|2646295_2647099_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_011887909.1\|2647101_2647785_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_011887910.1\|2647834_2648353_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_008881074.1\|2648349_2649216_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_008881075.1\|2649236_2650259_-	rod shape-determining protein	NA	NA	NA	NA
WP_171355528.1\|2650416_2651088_-	DNA repair protein RadC	NA	NA	NA	NA
WP_008881078.1\|2651212_2651794_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_041264888.1\|2651911_2653030_-	hypothetical protein	NA	NA	NA	NA
WP_029760654.1\|2653146_2653581_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_011887912.1\|2653599_2654268_-	pilus assembly protein PilO	NA	NA	NA	NA
WP_008881082.1\|2654264_2654840_-	fimbrial protein	NA	NA	NA	NA
WP_008881083.1\|2654829_2655762_-	pilus assembly protein PilM	NA	NA	NA	NA
WP_011887913.1\|2655787_2656534_-	prepilin peptidase	NA	NA	NA	NA
WP_174375698.1\|2656542_2657022_-	type II secretion system protein	NA	NA	NA	NA
WP_011887914.1\|2657108_2658320_-	type II secretion system F family protein	NA	NA	NA	NA
WP_011887915.1\|2658306_2659362_-	type IV pilus twitching motility protein PilT	NA	NA	NA	NA
WP_008881088.1\|2659374_2661039_-	Flp pilus assembly complex ATPase component TadA	NA	NA	NA	NA
WP_008881089.1\|2661035_2662403_-	VanW family protein	NA	NA	NA	NA
WP_011887916.1\|2662772_2664119_-	hypothetical protein	NA	NA	NA	NA
WP_008881091.1\|2664243_2664855_+	hypothetical protein	NA	NA	NA	NA
WP_008881092.1\|2664838_2665414_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_008881093.1\|2665429_2667007_+	hypothetical protein	NA	NA	NA	NA
WP_011887917.1\|2667115_2669122_-	VWA domain-containing protein	NA	NA	NA	NA
WP_008881095.1\|2669180_2670485_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_008881096.1\|2670615_2673258_-\|tRNA	valine--tRNA ligase	A0A1V0S951	Catovirus	5.5e-165	42.0
WP_008881097.1\|2673842_2674031_+	hypothetical protein	NA	NA	NA	NA
WP_008881098.1\|2674027_2675059_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_008881099.1\|2675102_2676167_-	stage VI sporulation protein D	NA	NA	NA	NA
WP_008881100.1\|2676285_2677575_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_011887919.1\|2677590_2678565_-	porphobilinogen synthase	NA	NA	NA	NA
WP_008881102.1\|2678565_2679336_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_008881103.1\|2679335_2680265_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_008881104.1\|2680280_2681096_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_011887920.1\|2681106_2682474_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_008881106.1\|2682638_2683124_+	hypothetical protein	NA	NA	NA	NA
WP_008881107.1\|2683197_2683785_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_011887921.1\|2683781_2686124_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	2.8e-184	45.0
WP_155121012.1\|2686236_2686380_-	hypothetical protein	NA	NA	NA	NA
WP_008881109.1\|2686393_2688070_-\|protease	ATP-dependent protease LonB	A0A076FMQ5	Aureococcus_anophage	1.8e-12	32.2
WP_011887922.1\|2688210_2689476_-\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	4.1e-150	67.7

DBSCAN-SWA_10

2869537 : 2878752

Staphylococcus_phage(57.14%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008880953.1\|2869537_2871124_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	7.3e-197	64.4
WP_008880954.1\|2871322_2871565_-	DUF2584 domain-containing protein	NA	NA	NA	NA
WP_008880955.1\|2871713_2872502_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.6e-33	36.9
WP_011888012.1\|2872720_2873725_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_008880957.1\|2873743_2874562_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.2e-31	34.6
WP_011888013.1\|2874548_2875358_+	ABC transporter permease	NA	NA	NA	NA
WP_029760561.1\|2875410_2875878_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	8.6e-21	36.8
WP_008880960.1\|2875936_2876275_-	hypothetical protein	NA	NA	NA	NA
WP_008880961.1\|2876528_2876924_-\|holin	phage holin family protein	A0A0N7GFE6	Paenibacillus_phage	1.8e-24	49.6
WP_008880962.1\|2877066_2877507_-	DNA starvation/stationary phase protection protein	A0A0A7RTZ1	Clostridium_phage	6.2e-53	68.5
WP_008880963.1\|2877601_2877817_+	YtzI protein	NA	NA	NA	NA
WP_008880964.1\|2877841_2878318_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_087960383.1\|2878515_2878752_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	3.9e-22	63.5

DBSCAN-SWA_11

2912774 : 2945358

Geobacillus_phage(40.0%)

tRNA,head,capsid,portal,terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008881002.1\|2912774_2913245_-\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_029760538.1\|2913983_2914487_+	DinB family protein	NA	NA	NA	NA
WP_008881005.1\|2914644_2915067_+	metallothiol transferase FosB	Q2LI91	Bacillus_phage	6.1e-42	68.1
WP_008881006.1\|2915375_2915795_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011888040.1\|2916281_2916626_-	hypothetical protein	NA	NA	NA	NA
WP_011888041.1\|2916644_2917106_-	DUF4879 domain-containing protein	O64027	Bacillus_phage	1.0e-10	30.4
WP_011888042.1\|2917619_2918282_+	hypothetical protein	D2XR34	Bacillus_phage	9.7e-18	58.0
WP_041264661.1\|2918381_2918597_-	hypothetical protein	Q0H253	Geobacillus_phage	9.7e-28	81.4
WP_011888043.1\|2918926_2923687_+	DEAD/DEAH box helicase	A0A2H4UVA3	Bodo_saltans_virus	3.2e-38	24.2
WP_011888044.1\|2923832_2924537_-	N-acetylmuramoyl-L-alanine amidase	E5DV68	Deep-sea_thermophilic_phage	9.5e-56	54.9
WP_041264663.1\|2924548_2924734_-	hypothetical protein	NA	NA	NA	NA
WP_011888046.1\|2924733_2925087_-	hypothetical protein	NA	NA	NA	NA
WP_011888047.1\|2925101_2927993_-	glycoside hydrolase	W8EK73	Geobacillus_phage	3.6e-234	43.8
WP_011888048.1\|2927989_2928787_-	hypothetical protein	W8EBC9	Geobacillus_phage	5.0e-53	43.9
WP_011888049.1\|2928791_2928989_-	hypothetical protein	W8ECV6	Geobacillus_phage	5.8e-11	56.5
WP_011888050.1\|2928985_2930479_-\|tail	phage tail protein	W8EEW0	Geobacillus_phage	1.3e-134	52.9
WP_011888051.1\|2930489_2931554_-	hypothetical protein	W8EIX3	Geobacillus_phage	3.8e-48	37.3
WP_011888052.1\|2931569_2932319_-\|tail	phage tail family protein	W8EK66	Geobacillus_phage	1.5e-51	40.0
WP_011888053.1\|2932315_2933878_-	membrane protein	A0A2H4JC82	uncultured_Caudovirales_phage	7.9e-18	48.5
WP_008880458.1\|2934090_2935236_-\|tail	phage tail tape measure protein	Q0H230	Geobacillus_phage	8.7e-99	72.2
WP_041264898.1\|2935426_2935855_-	hypothetical protein	NA	NA	NA	NA
WP_008881957.1\|2935875_2936046_-	hypothetical protein	NA	NA	NA	NA
WP_008881958.1\|2936094_2937045_-	hypothetical protein	NA	NA	NA	NA
WP_011888057.1\|2937065_2937503_-	hypothetical protein	F8SK39	Pseudomonas_phage	1.6e-05	45.9
WP_008881960.1\|2937531_2937975_-	hypothetical protein	NA	NA	NA	NA
WP_041264666.1\|2937971_2938397_-	HK97 gp10 family phage protein	D4P800	Rhodococcus_phage	1.2e-05	41.5
WP_011888059.1\|2938402_2938828_-	hypothetical protein	NA	NA	NA	NA
WP_011888060.1\|2938834_2939185_-	hypothetical protein	NA	NA	NA	NA
WP_011888061.1\|2939201_2940119_-\|capsid	phage major capsid protein	Q9HH50	Methanothermobacter_phage	1.0e-41	38.9
WP_041264668.1\|2940151_2941573_-	structural protein	Q9HH51	Methanothermobacter_phage	5.3e-37	48.5
WP_011888063.1\|2941640_2942507_-\|head	phage head morphogenesis protein	NA	NA	NA	NA
WP_011888064.1\|2942499_2943945_-\|portal	phage portal protein	A0A2L1IVM1	Streptomyces_phage	3.0e-48	31.3
WP_041264670.1\|2943963_2945358_-\|terminase	phage terminase large subunit	A0A2K9V3I6	Faecalibacterium_phage	5.0e-149	56.0

DBSCAN-SWA_12

2949041 : 2966084

Thermus_phage(19.05%)

integrase

attL 2948984:2949000|attR 2983389:2983405

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2948984:2949000	attL	NA	NA	NA	NA
WP_011888070.1\|2949041_2949347_-	hypothetical protein	A0A1L2JY44	Aeribacillus_phage	1.3e-12	66.7
WP_011888071.1\|2949545_2950682_-	hypothetical protein	NA	NA	NA	NA
WP_011888072.1\|2950804_2951266_-	hypothetical protein	NA	NA	NA	NA
WP_011888073.1\|2951684_2952146_-	ArpU family transcriptional regulator	S6AVV9	Thermus_phage	2.1e-48	68.8
WP_081157681.1\|2952720_2952831_+	YjcZ family sporulation protein	NA	NA	NA	NA
WP_011888074.1\|2952827_2953235_-	hypothetical protein	S6AVV9	Thermus_phage	7.8e-18	83.9
WP_011888075.1\|2953509_2953872_+	response regulator	Q56AR1	Bacillus_thuringiensis_phage	2.5e-07	34.7
WP_011888076.1\|2954113_2954542_-	hypothetical protein	E5DV97	Deep-sea_thermophilic_phage	1.2e-45	60.7
WP_011888077.1\|2954582_2955005_-	hypothetical protein	A6M9A1	Geobacillus_virus	9.1e-46	62.7
WP_008881975.1\|2955017_2955509_-	hypothetical protein	A0A0C5AFC9	Paenibacillus_phage	1.0e-32	51.4
WP_011888079.1\|2955522_2956071_-	dUTP diphosphatase	A0A290GJJ6	Caldibacillus_phage	4.1e-30	39.3
WP_013144080.1\|2956089_2956272_-	hypothetical protein	NA	NA	NA	NA
WP_041264900.1\|2956363_2956657_-	hypothetical protein	NA	NA	NA	NA
WP_011888082.1\|2956735_2957233_-	single-stranded DNA-binding protein	A6M990	Geobacillus_virus	1.8e-45	58.5
WP_011888083.1\|2957322_2957781_-	HNH endonuclease	A6M989	Geobacillus_virus	1.7e-37	59.0
WP_011888084.1\|2957777_2958206_-	hypothetical protein	NA	NA	NA	NA
WP_011888085.1\|2958210_2959458_-	DNA helicase	A0A0U4B0A1	Bacillus_phage	2.4e-78	37.8
WP_008881985.1\|2959454_2959718_-	hypothetical protein	NA	NA	NA	NA
WP_011888086.1\|2959733_2960579_-	DnaD domain protein	A0A0U4JX08	Bacillus_phage	1.1e-39	67.3
WP_008881988.1\|2960826_2960988_-	hypothetical protein	NA	NA	NA	NA
WP_011888087.1\|2960984_2961686_-	ERF family protein	A0A2H4IYS6	uncultured_Caudovirales_phage	4.7e-39	39.9
WP_011888088.1\|2961682_2962159_-	siphovirus Gp157 family protein	E5DV79	Deep-sea_thermophilic_phage	3.9e-53	73.0
WP_011888089.1\|2962182_2962377_-	hypothetical protein	A6M980	Geobacillus_virus	3.2e-22	73.3
WP_011888090.1\|2962377_2962719_-	hypothetical protein	NA	NA	NA	NA
WP_011888091.1\|2963069_2963345_-	hypothetical protein	Q0H238	Geobacillus_phage	1.3e-40	92.3
WP_011888092.1\|2963316_2963583_-	DUF771 domain-containing protein	A0A1B1IMW0	Lactococcus_phage	2.2e-05	35.7
WP_041264902.1\|2963584_2963791_-	helix-turn-helix transcriptional regulator	S6BA02	Thermus_phage	6.9e-23	80.0
WP_011888093.1\|2963981_2964452_+	helix-turn-helix domain-containing protein	S6C481	Thermus_phage	3.2e-68	88.2
WP_011888094.1\|2964472_2964913_+	ImmA/IrrE family metallo-endopeptidase	Q0H245	Geobacillus_phage	1.0e-71	91.5
WP_011888095.1\|2964947_2966084_+\|integrase	site-specific integrase	A8ATX2	Listeria_phage	2.3e-96	48.3
2983389:2983405	attR	NA	NA	NA	NA

DBSCAN-SWA_13

3471661 : 3533216

Bacillus_phage(23.08%)

tRNA,transposase,integrase,coat

attL 3529718:3529732|attR 3534304:3534318

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008880753.1\|3471661_3472234_+\|coat	spore coat protein GerQ	NA	NA	NA	NA
WP_008880754.1\|3472370_3472871_+	hypothetical protein	NA	NA	NA	NA
WP_008880755.1\|3472890_3473793_+	prenyltransferase	NA	NA	NA	NA
WP_008880756.1\|3473846_3474218_-	DUF423 domain-containing protein	NA	NA	NA	NA
WP_008880757.1\|3474354_3474600_-	hypothetical protein	NA	NA	NA	NA
WP_008880758.1\|3474843_3475143_-	YwdI family protein	NA	NA	NA	NA
WP_008880759.1\|3475159_3475849_-	uracil-DNA glycosylase	A0A0B5IW78	Pandoravirus	7.9e-55	50.2
WP_011888424.1\|3476358_3476838_+	anti-sigma B factor RsbW	NA	NA	NA	NA
WP_008880762.1\|3476797_3477568_+	sigma-70 family RNA polymerase sigma factor	A0A0A0RV91	Bacillus_phage	1.2e-16	32.2
WP_041264770.1\|3477617_3479525_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_029761098.1\|3479742_3480378_-	FMN-dependent NADH-azoreductase	NA	NA	NA	NA
WP_008880765.1\|3480559_3480709_-	hypothetical protein	NA	NA	NA	NA
WP_029761097.1\|3480974_3482357_-\|tRNA	glycine--tRNA ligase	A0A1V0SAN4	Catovirus	3.3e-52	30.3
WP_011888429.1\|3482621_3483473_-	glycosyltransferase	NA	NA	NA	NA
WP_008880768.1\|3483695_3484892_-	MFS transporter	NA	NA	NA	NA
WP_008880769.1\|3485222_3485717_-	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_011888430.1\|3485809_3486877_-	tartrate dehydrogenase	NA	NA	NA	NA
WP_008880771.1\|3487016_3488252_+	PucR family transcriptional regulator	NA	NA	NA	NA
WP_008880772.1\|3488369_3489503_+	alanine dehydrogenase	NA	NA	NA	NA
WP_008880773.1\|3489821_3490637_+	pyridoxine/pyridoxal/pyridoxamine kinase	NA	NA	NA	NA
WP_008880775.1\|3491049_3492507_-	sodium/proline symporter PutP	NA	NA	NA	NA
WP_011888432.1\|3492916_3493738_+	basic amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_008880777.1\|3493808_3494465_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_011888433.1\|3494461_3495184_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.6e-34	41.8
WP_011888434.1\|3495378_3495678_-	cytochrome aa3 quinol oxidase subunit IV	NA	NA	NA	NA
WP_011888435.1\|3495679_3496294_-	cytochrome aa3 quinol oxidase subunit III	NA	NA	NA	NA
WP_011888436.1\|3496297_3498244_-	cytochrome aa3 quinol oxidase subunit I	NA	NA	NA	NA
WP_011888437.1\|3498261_3499170_-	cytochrome aa3 quinol oxidase subunit II	NA	NA	NA	NA
WP_029761091.1\|3499444_3500167_-	RNA methyltransferase	NA	NA	NA	NA
WP_008880787.1\|3500401_3501790_+	amino acid permease	NA	NA	NA	NA
WP_108437899.1\|3501935_3502304_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	2.3e-08	45.9
WP_008880788.1\|3502901_3504287_-	transcriptional regulator	NA	NA	NA	NA
WP_008880789.1\|3504471_3505998_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011888441.1\|3506165_3507128_+	mannose-6-phosphate isomerase, class I	NA	NA	NA	NA
WP_008880791.1\|3507288_3508443_-	glycerate kinase	W6LM47	Streptococcus_phage	1.5e-53	43.9
WP_008880792.1\|3509061_3510300_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_099233577.1\|3510629_3511049_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_011888444.1\|3511259_3511877_+	hypothetical protein	NA	NA	NA	NA
WP_011886641.1\|3511885_3512776_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_011888445.1\|3512971_3513676_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_193338207.1\|3513852_3514701_+\|transposase	transposase	NA	NA	NA	NA
WP_029761088.1\|3514929_3515478_-	flavodoxin family protein	NA	NA	NA	NA
WP_041264774.1\|3515615_3516095_-	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_008880799.1\|3516178_3516328_-	CxxH/CxxC protein	NA	NA	NA	NA
WP_035499498.1\|3516394_3517612_-	trypsin-like peptidase domain-containing protein	A0A1B1IT49	uncultured_Mediterranean_phage	3.6e-18	27.3
WP_008880801.1\|3517713_3518508_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	1.6e-43	36.9
WP_008880802.1\|3518514_3519297_-	two-component system regulatory protein YycI	NA	NA	NA	NA
WP_008880803.1\|3519283_3520612_-	hypothetical protein	NA	NA	NA	NA
WP_011888451.1\|3520604_3522434_-	cell wall metabolism sensor histidine kinase WalK	A0A1V0SGX0	Hokovirus	1.1e-23	27.5
WP_008880805.1\|3522440_3523154_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.0e-44	42.3
WP_008880807.1\|3523378_3524665_-	adenylosuccinate synthase	L7Y4J5	Megavirus	1.7e-71	36.4
WP_008880808.1\|3524824_3526189_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.8e-122	52.4
WP_011888453.1\|3526283_3526733_-	50S ribosomal protein L9	NA	NA	NA	NA
WP_011888454.1\|3526729_3528706_-	DHH family phosphoesterase	NA	NA	NA	NA
WP_008880811.1\|3528752_3529679_-	YybS family protein	NA	NA	NA	NA
3529718:3529732	attL	NA	NA	NA	NA
WP_008881893.1\|3529965_3531105_+\|integrase	tyrosine-type recombinase/integrase	A0A0A8WIE1	Clostridium_phage	1.2e-12	27.2
WP_011888455.1\|3531101_3533216_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
3534304:3534318	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_009328

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection