CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_008750	Shewanella sp. W3-18-1, complete genome	7 crisprs	DEDDh,cas3,WYL,csa3,DinG,cas6f,cas7f,cas5f,cas8f,cas3-cas2,cas1,RT	1	28	11	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_008750_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008750_1

1666282-1666431

Orphan

Consensus_repeat	Method
TGGATCCCCGCGTGCGCGGGGATGACGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_008750_1

>merge|NC_008750|1|1666282-1666431|CRISPRCasFinder
TGGATCCCCGCGTGCGCGGGGATGACGCGATTTAAGTTCTGAGGTTTCTTACAATCACAGGTGGATCCCCGCGTGCGCGGGGATGACGCTGGTCTTAATGGTTTGGATGGTCTTAATGGAGCTGGATCCCCGCGTGTGCGAGGATGACGG

>NC_008750|1|1|1666282-1666431|CRISPRCasFinder
TGGATCCCCGCGTGCGCGGGGATGACGC	GATTTAAGTTCTGAGGTTTCTTACAATCACAGG
TGGATCCCCGCGTGCGCGGGGATGACGC	TGGTCTTAATGGTTTGGATGGTCTTAATGGAGC
TGGATCCCCGCGTGTGCGAGGATGACGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008750.1\|WP_011788814.1\|1661411_1662359_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133039
NC_008750.1\|WP_011788813.1\|1660804_1661419_+\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NC_008750.1\|WP_041408143.1\|1670947_1671286_-\|hypothetical-protein	unknown	unknown	unknown
NC_008750.1\|WP_011788827.1\|1679564_1679816_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374895
NC_008750.1\|WP_011788812.1\|1660208_1660769_+\|acyltransferase	unknown	unknown	gnl\|CDD\|100053
NC_008750.1\|WP_011788809.1\|1657078_1657627_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl\|CDD\|376414
NC_008750.1\|WP_011788826.1\|1678706_1679417_-\|YjbF-family-lipoprotein	unknown	unknown	gnl\|CDD\|378557
NC_008750.1\|WP_011788825.1\|1677912_1678698_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368817
NC_008750.1\|WP_011788821.1\|1671444_1671891_-\|copper-resistance-protein-NlpE	unknown	unknown	gnl\|CDD\|377235
NC_008750.1\|WP_011788817.1\|1664546_1664855_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198395
NC_008750.1\|WP_011788811.1\|1659094_1660204_+\|DegT/DnrJ/EryC1/StrS-family-aminotransferase	unknown	unknown	gnl\|CDD\|99740
NC_008750.1\|WP_011788822.1\|1672264_1673614_+\|GAF-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_008750.1\|WP_011788819.1\|1668547_1669621_+\|UDP-N-acetylglucosamine--undecaprenyl-phosphate-N-acetylglucosaminephosphotransferase	unknown	unknown	gnl\|CDD\|131433
NC_008750.1\|WP_011788818.1\|1667283_1667820_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl\|CDD\|380337
NC_008750.1\|WP_011788823.1\|1674396_1674699_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198395
NC_008750.1\|WP_011788815.1\|1662510_1663761_-\|IS4-like-element-IS10A-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_008750.1\|WP_011788824.1\|1675546_1677913_-\|YjbH-domain-containing-protein	unknown	unknown	gnl\|CDD\|377600
NC_008750.1\|WP_083758260.1\|1663816_1664164_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224013
NC_008750.1\|WP_011788810.1\|1657626_1659057_+\|lipopolysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240532
NC_008750.1\|WP_041408137.1\|1665408_1665645_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008750.1\|WP_011788814.1\|1661411_1662359_+\|glycosyltransferase	gnl\|CDD\|133039	cd04196, GT_2_like_d, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	4.86691e-39
NC_008750.1\|WP_011788813.1\|1660804_1661419_+\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	4.83292e-69
NC_008750.1\|WP_011788827.1\|1679564_1679816_-\|hypothetical-protein	gnl\|CDD\|374895	pfam16940, Tic110, Chloroplast envelope transporter. Tic110 is a family of chloroplast envelope proteins. Some are involved in protein translocation and others are neurotransmitter receptor, cys loop, ligand-gated ion channel or LIC proteins.	0.00486456
NC_008750.1\|WP_011788812.1\|1660208_1660769_+\|acyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	8.47454e-26
NC_008750.1\|WP_011788809.1\|1657078_1657627_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl\|CDD\|376414	pfam00908, dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase. This family catalyze the isomerisation of dTDP-4-dehydro-6-deoxy -D-glucose with dTDP-4-dehydro-6-deoxy-L-mannose. The EC number of this enzyme is 5.1.3.13.	8.3053e-110
NC_008750.1\|WP_011788826.1\|1678706_1679417_-\|YjbF-family-lipoprotein	gnl\|CDD\|378557	pfam11102, YjbF, Group 4 capsule polysaccharide lipoprotein gfcB, YjbF. This family includes lipoprotein GfcB (YmcC), involved in group 4 capsule polysaccharide formation. YjbF is a family of Gram-negative bacterial outer-membrane lipoproteins, predicted to be a beta-barrel and possibly a porin that is one of four gene-products expressed from an operon, yjbEFGH, which is regulated by the Rcs phosphorelay in a RcsA-dependent manner, similar to that of other exopolysaccharide biosynthetic pathways. It is highly possible that the yjbEFGH operon encodes a system involved in EPS secretion since none of the products is predicted to have enzymic activity, the products are all secreted and YbjF and H are predicted to be beta-barrel lipoproteins similar to porins. It may be that the operon products play some role in biofilm formation and/or matrix production.	1.04004e-74
NC_008750.1\|WP_011788825.1\|1677912_1678698_-\|hypothetical-protein	gnl\|CDD\|368817	pfam06251, Caps_synth_GfcC, Capsule biosynthesis GfcC. Many bacteria are covered in a layer of surface-associated polysaccharide called the capsule. These capsules can be divided into four groups depending upon the organisation of genes responsible for capsule assembly, the assembly pathway and regulation. This family plays a role in group 4 capsule biosynthesis. These proteins have a beta-grasp fold. Two beta-grasp domains, D2 and D3, are arranged in tandem. There is a C-terminal amphipathic helix which packs against D3. A helical hairpin insert in D2 binds to D3 and constrains its position, a conserved arginine residue at the end of this hairpin is essential for structural integrity.	2.64272e-57
NC_008750.1\|WP_011788821.1\|1671444_1671891_-\|copper-resistance-protein-NlpE	gnl\|CDD\|377235	pfam04170, NlpE, NlpE N-terminal domain. This family represents a bacterial outer membrane lipoprotein that is necessary for signalling by the Cpx pathway. This pathway responds to cell envelope disturbances and increases the expression of periplasmic protein folding and degradation factors. While the molecular function of the NlpE protein is unknown, it may be involved in detecting bacterial adhesion to abiotic surfaces. In Escherichia coli and Salmonella typhi, NlpE is also known to confer copper tolerance in copper-sensitive strains of Escherichia coli, and may be involved in copper efflux and delivery of copper to copper-dependent enzymes.	1.15953e-36
NC_008750.1\|WP_011788817.1\|1664546_1664855_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198395	cd10448, GIY-YIG_unchar_3, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	2.01907e-51
NC_008750.1\|WP_011788811.1\|1659094_1660204_+\|DegT/DnrJ/EryC1/StrS-family-aminotransferase	gnl\|CDD\|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	6.12781e-143
NC_008750.1\|WP_011788822.1\|1672264_1673614_+\|GAF-domain-containing-sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.0787e-33
NC_008750.1\|WP_011788819.1\|1668547_1669621_+\|UDP-N-acetylglucosamine--undecaprenyl-phosphate-N-acetylglucosaminephosphotransferase	gnl\|CDD\|131433	TIGR02380, ECA_wecA, undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase. Members of this family are the WecA enzyme of enterobacterial common antigen biosynthesis, undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase. This family represents one narrow clade, and closely related sequences outside this clade may represent enzymes that catalyze the same specific reaction, but in the context of different pathways. A His-rich motif in a cytosolic loop of this integral membrane protein, shown critical to enzymatic activity for WecA is variously present or absent in the clade that includes Bacillus subtilis TagO teichoic acid biosynthesis enzyme, which may catalyze the same reaction as WecA. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	2.06645e-163
NC_008750.1\|WP_011788818.1\|1667283_1667820_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl\|CDD\|380337	cd00438, cupin_RmlC, RmlC carbohydrate epimerase, involved in dTDP-L-rhamnose production. RmlC (deoxythymidine diphosphate (dTDP)-4-keto-6-deoxy-D-hexulose 3, 5-epimerase or dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; also known as RfbC) is a carbohydrate epimerase involved in the production of dTDP-L-rhamnose, a precursor of the bacterial cell wall constituent, L-rhamnose. L-Rhamnose (6-deoxy-l-mannose) plays an important role in the cell-wall structure of many bacterial species. It has been found to contribute to the virulence of several species, including the Gram-negative Salmonella enterica and Vibrio cholerae, where it is present as a part of the O-antigen, and is essential for the growth of Gram-positive bacteria such as Streptococcus pyogenes. RmlC converts dTDP-6-deoxy-D-xylo-4-hexulose to dTDP-6-deoxy-L-xylo-hexulose by catalyzing the epimerization of the 5-methyl and 3-hydroxyl groups of hexulose, the third of four steps in the dTDP-L-rhamnose biosynthetic pathway. RmlC belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.35679e-88
NC_008750.1\|WP_011788823.1\|1674396_1674699_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198395	cd10448, GIY-YIG_unchar_3, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	8.93388e-52
NC_008750.1\|WP_011788815.1\|1662510_1663761_-\|IS4-like-element-IS10A-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	7.04672e-13
NC_008750.1\|WP_011788824.1\|1675546_1677913_-\|YjbH-domain-containing-protein	gnl\|CDD\|377600	pfam06082, YjbH, Exopolysaccharide biosynthesis protein YbjH. YjbH is a family of Gram-negative beta-barrel outer-membrane lipoproteins that act as putative porins. YbjH is one of four gene-products expressed from an operon, yjbEFGH, which is regulated by the Rcs phosphorelay in a RcsA-dependent manner, similar to that of other exopolysaccharide biosynthetic pathways. It is highly possible that the yjbEFGH operon encodes a system involved in EPS secretion since none of the products is predicted to have enzymic activity, the products are all secreted and YbjH and F are predicted to be beta-barrel lipoproteins similar to porins. It may be that the operon products play some role in biofilm formation and/or matrix production.	0
NC_008750.1\|WP_083758260.1\|1663816_1664164_+\|hypothetical-protein	gnl\|CDD\|224013	COG1088, RfbB, dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane].	9.12512e-45
NC_008750.1\|WP_011788810.1\|1657626_1659057_+\|lipopolysaccharide-biosynthesis-protein	gnl\|CDD\|240532	cd13127, MATE_tuaB_like, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. This family might function as a translocase for lipopolysaccharides and participate in the biosynthesis of cell wall components such as teichuronic acid. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	1.36367e-132

>NC_008750.1|WP_041408137.1|1665408_1665645_+|hypothetical-protein
MREDDGKGENYALSVIPAKAGIHSKVFCYLKYKANYLTADPRVREDDDEGENYALSVIPAKAGIHSKVFYYLEYKVRT
>NC_008750.1|WP_011788817.1|1664546_1664855_+|GIY-YIG-nuclease-family-protein
MQPYVYIMASQFNGTLYIGVTSQLEQRVWQHKNAIIDGFTHKYKVDQLVYFEAHVSMYDAICREKQLKKWRREWKIDLINSQNPKWQDLWYTVIAGSPHTRG
>NC_008750.1|WP_083758260.1|1663816_1664164_+|hypothetical-protein
MLQVRALFLVATQGRLGQTYNIGGSNERSNIEVVQKICDLLEELAPTHPHAFAVNGIGFRGLIQHVEDRPGYDVRYAIDASKLEHELGWQPYESFESGLRKTVKWIVEQSDEVRS
>NC_008750.1|WP_011788815.1|1662510_1663761_-|IS4-like-element-IS10A-family-transposase
MIKWFLQKLHLDNKMREANILQHSLHQYCPELHLKRLNSLMLASKALIECKTLTLTELGRNLPTTARTKHNIKRIDRLLGNTHLHQERLAVYQWHASLICSGNPMPIVLVDWSDIREHKRIMALRASIAFNGRSITLYEKSYPLSEQCSKASHNGFLADLAKILPLHVTPLIVTDAGFKVPWYKEVEAHGWFWLSRIRGTVQFADIGAENWRAVRSTHDLANGQAKSLGCKTLTKTNPINCHLTLYRSKPKGRTNQRSTRTNCHHPSAKTYSTSAKEPWVLASNLPPESRSPKQLVNLYAKRMQIEETFRDLKSPAYGFGLRQSRTNSPERFDIILLIALMVQCLLWLVGLHAQQQGWDKHFQANTIGHRTVLSTIRLGLEVLRRPDYQITEKELLAAWVLFANQLLKYGYAMADL
>NC_008750.1|WP_011788814.1|1661411_1662359_+|glycosyltransferase
MNNSMVTVCIVTYNQKKYIEQCLDSIVNQKTDYSYQVIISDDASTDGTSEICAEYAKRYQFINHIRHATNIGAYENFKYVHRQAKTQYVSHCDADDSWHEDKLEKQIKFLEGNSDCCAVYSNAIVINEHGTRIGVFNNSEEIPSKITIGYLLEKSNFLNNSSMIYRRDMIGDIFDADGKVVDYRIHIHLANCGLLGYIKESLAFYRKGAAGGLCLNAPAAVGQLVHEARLDGIKNAKLSIVDFSKIKTNAWYGKLTCFLKRNKFMYARHTEVEALIVDYDFIQSVMFLFFEIVIYFFCKMKEKLSINKNIILYHR
>NC_008750.1|WP_011788813.1|1660804_1661419_+|CatB-related-O-acetyltransferase
MFFYLLKMFKVKFFSSRNQRLNDRITTIRGEGTYGPEPKLIGPHNVVEQLHFGSSIGKYCSIAAGIKFLFRGKHNTNWVSTYPFQVMMGLDVPLNDLTLHAPVKIGNDVWIATNVKIMQGVTIGDGAIIAQESLVTKDVPPYAIVGGNPARIIRYRFEPDEIQELLNLQWWNLPKNKIVLIAKYLTSQDVNECIKQIKMVKDNE
>NC_008750.1|WP_011788812.1|1660208_1660769_+|acyltransferase
MAFLTEQQLNSMGFAALGYNVFISDKASIYGVSRIRIGNNVRIDDFCVLSAGEGGIEIGNYIHIAVYSSLIGAGKITLSDFSNISSKVAIYSSNDDYSGEYMTNPMVPAKYTNVIHADVTIGKHVIIGSGSVVLPGVTLFAGAAIGSLSLVTKDCEAFGVYIGSPARKIKNRKRELLAVENNFIEK
>NC_008750.1|WP_011788811.1|1659094_1660204_+|DegT/DnrJ/EryC1/StrS-family-aminotransferase
MSNKNIPVTQPFLPELNEFIPYLEQIWDNRWLTNNGPFHQQLEAKLCEYLGVEHISLFNNATIALITALQSLRVTGEVITTPYSFVATSHSIMWNGLEPVFVDVDPTTFNIDPAKIEAAITPRTTAIMPVHCYSNPCDVEAIQNIADNYGLKVIYDAAHAFGVNYKGESLLKWGDLSILSFHATKVFNTFEGGAIISPDAKTKQRIDRLKNFGIADELTVTAPGINGKMSEINAAFGLVQLKHIDNAMAQRRAVDVRYREALADVTGITLYKHDSNANSNFSYFPILVEADYPLSRDELYDKLKNNHILSRRYFYPLISNMPMYRGLPSAAISYLPQANQLADKVLCLPIFNELTVDEQQQVIELIKGN
>NC_008750.1|WP_011788810.1|1657626_1659057_+|lipopolysaccharide-biosynthesis-protein
MSDLATKTKKGLQWSAIERLLTQGMQLGITLLLARLLGPTAFGLVGMLTVFIAIANVFVDSGFTSALIRKSDRSESDLVTAFYYNIGMAAVCYLALYISAPAIAEFYQQSELQSLLRVLGITVLINAFTLIPRVKLNVVMDFKTQAKISIISVLISGSISMTLAINGLGVWALVIQTLINSSCTTLLFNLFVPWLPRGNLTKASFSYLFGYGSKILISSLLEVIYSNIYQIIIGKKFSPAVVGQFTQANQLASVPAMTLTAIIQRVTFPLFSQLQDNPEKMESAYRLTLKTAAMVIFPLIVGLGLIAQPLLTELLGAQWQDAAGLLSVLCLGYMLYPIHAINLNLLQITGRSDLFLKLEVFKKIIGVVILLNTIRYGVLGMCIGLSVTSYVALLLNTYYTAKLTRISQWQQCKDLTPIWLAVMLSAVLAYATGLSWQALPWLQILINISVALLSYSLYLVLAQRPLLLQLQSALRR
>NC_008750.1|WP_011788809.1|1657078_1657627_+|dTDP-4-dehydrorhamnose-3,5-epimerase
MKIIDTKIPDVKIIEPRVFGDDRGFFFESFNQQQFEAAIGYPVNFVQDNHSKSSKGVLRGLHYQLAPHVQSKLVRCVVGEVFDVAVDIRQSSPTFGQWVGVHLSAENKRQLWIPEGFAHGFVTLRETAEFLYKTTNYYCAASDRGIQWNDEKLAVAWPIEGLILTLSDKDKRQPIFEKAEYL
>NC_008750.1|WP_011788818.1|1667283_1667820_+|dTDP-4-dehydrorhamnose-3,5-epimerase
MKCIETELAEVLVFEPQRFGDERGFFMETFRQSYFDACFTERGFSLPIFVQENHSRSQQNVLRGLHFQRLQPQGKLVRVCTGSIFDVAVDIRANSPTYGQWVGRVLSADNRLQMWTPPGFAHGFYVLSEFADVIYRCTDYYAPHDEYVLGWNNTDFSIDWPLIAEPLLSDRDAIAART
>NC_008750.1|WP_011788819.1|1668547_1669621_+|UDP-N-acetylglucosamine--undecaprenyl-phosphate-N-acetylglucosaminephosphotransferase
MSTNIAVLFVFLVSFISLFVFRKVAQRIGLVDKPNERKHHKGQIPLVGGISIFFTIILALFLTPELLLAPQLYAGCAFILVVIGAIDDRYDISFKFRLVVQAAVSMLMIVLGERSLHNLGYLMGSEAIHLPEPISILLTVFAVIGAINAFNMVDGIDGLLGGLASVTFGGLGILFYFNGMQGFAIFCVLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGDRATALRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRMGLSSHSSLMVICTAAAIMVAVGIWSELAKIDENIMFLAFLATFALYFGLINNIWRITAFWRKDIKISKSI
>NC_008750.1|WP_041408143.1|1670947_1671286_-|hypothetical-protein
MFHTKYDIPTLHGVQIQEVERFIRKSPGAVIDAGIQLLAFKSPTFTVPKDVTVDSRLRGNDKAVILANAGIQLWLLSHSLLKHPKTLLWIPAFAGMTKELESYCGFPPPTRE
>NC_008750.1|WP_011788821.1|1671444_1671891_-|copper-resistance-protein-NlpE
MKQSLLGIALLALFTTACTDPAPKPTDTTPAQTESAANTPTGDTSQNSLDWPGNYEGVLPCASCEGIETHISLKADNSFELKSIYLGKDEKIFKVTGTAVWDAQGQKITLADGTQYLVGENQLIMLDTEGKRITGELAANYVLKKKSE
>NC_008750.1|WP_011788822.1|1672264_1673614_+|GAF-domain-containing-sensor-histidine-kinase
MTRMFDRILFDVSQSPLIDKGDLTVAAQLIVSSVCKGLNVKRVGIWLLSEDRQSISCFYLSHHPQLEQTLTLARVQYPHYFDLLDTERTIVLDHRQLDFTTQELASTYFNANNITAILASPIRHDGKMVGIICVEHQGEPREWMPDDKAFVSTLAEIFARSISARDILDYQRQLKVVNADLELRTQELEAALAHLSATQNHLIEKEKMAALGSLVAGVAHEVNTPLGIAVTSVTHCLDELALLKRFFESNELDQEKFLNFMTTMQDGLSLVDRNLARAAELVHNFKRTAADQSIWERERFNLKAYILQVFSSLKPLMRKKSISLTINVDDGIYLYSYPGAIAQIFTNLVSNSFRHGFPDNFTGEKQIIVEADKTSSTINIIYQDSGVGMSDDIKARAFEPFFTTAKQSGGTGLGMSIIHNLVTQKLNGRISLISAPNQGVKIEMQLPEE
>NC_008750.1|WP_011788823.1|1674396_1674699_+|GIY-YIG-nuclease-family-protein
MQPYVYIMASQFNGTLYIGVTSHLEQRIWQHKNAIVDGFTHKYKVDQLVYFEVHASMYDAICREKQLKKWRREWKINLINSQNPKWEDLWYTVIVGSPHR
>NC_008750.1|WP_011788824.1|1675546_1677913_-|YjbH-domain-containing-protein
MKKPSHSIHTLGRLSALSLALLPLLHASADEFAYPTLLPSQSDFGGVGLMQMPTGRMAAEGEFNFSTTYNDEYQHYTASVQLFPWFETTVRYTLVHDLLYSNDPNFSGNTKYTDKGIDFKVRLLEESYWLPETSIGVRDFGGTGLFDGEFIAATKRVGPLDFTLGIGWGYIGNSGNLTSDKKDLNYNCDRDTSYGGKGGEVDYQRWFKGCAALFGGVEYQTPWDPLRVKVEYDANDYESDFPVVRGGIDMTQDSKFNYGLLYRFGNWGDLHLSYERGNTWTLGFSLQTNFNTLTQIKRDPAAAKYKPLPAAPMTQAQLAQTEDTPSSVASIDTASYQESNTDNIQADTALNVDSTVNTASLSTAATETTDWNKVAQDLQRIAGYNNAKIYLAADRITVVGEQTKFRDRSEAHHRTATILANNSALSQIKEYRLIETHYSQPITETRIDAEKFAKVANFAYLNAKVSDASQVSVPSAPQGTLVTQTNTDWLDKLGFDVSPTMVQSFGGSEGFYMFNIGVTGSANYKFTDNFEFGGSLYLNLYDNYDKFLYDVPPDGTDLKRVRTLIRQYVHDNPVRMNNLQLTWMDNLSDNVSYQAYGGYLEMMYGGVGTEFMYRPLNSQWAFGIDVNYVKQRDPDNMFGFFKDEHQFDPLIGRAYRVQTGAMTGHATVYYQPEWFPNTLLRVSAGQYLTEDKGVTVDLSKQFDSGVIVGAFATKTNLSADEYGEGSFTKGFYISVPFDLMTIKSTHSRAFLSWIPLTRDGGQMLGRKYNLFDVTDARAPWYTKPSTEK
>NC_008750.1|WP_011788825.1|1677912_1678698_-|hypothetical-protein
MKSYLTPLALLVSSVFSTVAHAETQLFVTTSSTLDAPLHIVYPTGIRIGQAVQDGLQQLPLYNKTNNKEVMPIYWLGAALVDLENTAVLETKRQQVLSQLAQMGEATNDSRYITKLAQLAQFLRGIKLGQRVMQPLDIDAIRITESYNAIIEGKYQLVLPPRPSTITLVGAVSQTGNMPWQSQASSKDYLQQAGLLENAETSFVWIIQPDGNAIRQPIAYWNYQAQDIAPGATLFVEFSSLFDGYANLNENIIELLKNRTL
>NC_008750.1|WP_011788826.1|1678706_1679417_-|YjbF-family-lipoprotein
MRINKNLVRLLTISTVLMGITGCSQRISALNDTIKLAFLGEDDVKLTSEQVKSNPYASIYAKIGDTPQAFVVLAFAEPKVTLSNVRPEPDSTELKWLSADNGMLVTINGRLIKTHNLLEGNLAAVESHEPDPIVLGLHLDNTPKTWTRTLDWQPGYHYGYKVTSQFKLIADENVLINDTPTQLLHYSETVSVEGLNIQYQNDFWLKPDNGHVVKSRQKIAPNLPFIDIILLKPFAS
>NC_008750.1|WP_011788827.1|1679564_1679816_-|hypothetical-protein
MKKTSLALVTALTMFASVSVNAAETETGTATGGATTGGAVGGLAAGAIAAGAVVAGVVVASNGSDGNPITSTGTTTTSNSGAN

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Crispr_ID: NC_008750_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008750_2

1670942-1671015

Orphan

Consensus_repeat	Method
CCTTCGTCATTCCCGCGTAGGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008750_2

>merge|NC_008750|2|1670942-1671015|CRISPRCasFinder
CCTTCGTCATTCCCGCGTAGGCGGAGGAAATCCACAGTAACTCTCTAACTCCTTCGTCATTCCCGCGAAGGCGG

>NC_008750|2|2|1670942-1671015|CRISPRCasFinder
CCTTCGTCATTCCCGCGTAGGCGG	AGGAAATCCACAGTAACTCTCTAACT
CCTTCGTCATTCCCGCGAAGGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008750.1\|WP_011788814.1\|1661411_1662359_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133039
NC_008750.1\|WP_011788828.1\|1680299_1681424_+\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|132848
NC_008750.1\|WP_011788824.1\|1675546_1677913_-\|YjbH-domain-containing-protein	unknown	unknown	gnl\|CDD\|377600
NC_008750.1\|WP_011788829.1\|1681566_1683282_-\|proline--tRNA-ligase	unknown	unknown	gnl\|CDD\|236405
NC_008750.1\|WP_011788827.1\|1679564_1679816_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374895
NC_008750.1\|WP_011788812.1\|1660208_1660769_+\|acyltransferase	unknown	unknown	gnl\|CDD\|100053
NC_008750.1\|WP_011788813.1\|1660804_1661419_+\|CatB-related-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
NC_008750.1\|WP_011788826.1\|1678706_1679417_-\|YjbF-family-lipoprotein	unknown	unknown	gnl\|CDD\|378557
NC_008750.1\|WP_011788825.1\|1677912_1678698_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368817
NC_008750.1\|WP_011788821.1\|1671444_1671891_-\|copper-resistance-protein-NlpE	unknown	unknown	gnl\|CDD\|377235
NC_008750.1\|WP_011788817.1\|1664546_1664855_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198395
NC_008750.1\|WP_011788811.1\|1659094_1660204_+\|DegT/DnrJ/EryC1/StrS-family-aminotransferase	unknown	unknown	gnl\|CDD\|99740
NC_008750.1\|WP_011788822.1\|1672264_1673614_+\|GAF-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_008750.1\|WP_011788819.1\|1668547_1669621_+\|UDP-N-acetylglucosamine--undecaprenyl-phosphate-N-acetylglucosaminephosphotransferase	unknown	unknown	gnl\|CDD\|131433
NC_008750.1\|WP_011788818.1\|1667283_1667820_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl\|CDD\|380337
NC_008750.1\|WP_011788823.1\|1674396_1674699_+\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198395
NC_008750.1\|WP_011788815.1\|1662510_1663761_-\|IS4-like-element-IS10A-family-transposase	unknown	unknown	gnl\|CDD\|376573
NC_008750.1\|WP_011788830.1\|1683495_1684125_-\|acyltransferase	unknown	unknown	gnl\|CDD\|100053
NC_008750.1\|WP_083758260.1\|1663816_1664164_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224013
NC_008750.1\|WP_041408137.1\|1665408_1665645_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008750.1\|WP_011788814.1\|1661411_1662359_+\|glycosyltransferase	gnl\|CDD\|133039	cd04196, GT_2_like_d, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	4.86691e-39
NC_008750.1\|WP_011788828.1\|1680299_1681424_+\|patatin-like-phospholipase-family-protein	gnl\|CDD\|132848	cd07209, Pat_hypo_Ecoli_Z1214_like, Hypothetical patatin similar to Z1214 protein of Escherichia coli. Patatin-like phospholipase similar to Z1214 protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	8.02865e-49
NC_008750.1\|WP_011788824.1\|1675546_1677913_-\|YjbH-domain-containing-protein	gnl\|CDD\|377600	pfam06082, YjbH, Exopolysaccharide biosynthesis protein YbjH. YjbH is a family of Gram-negative beta-barrel outer-membrane lipoproteins that act as putative porins. YbjH is one of four gene-products expressed from an operon, yjbEFGH, which is regulated by the Rcs phosphorelay in a RcsA-dependent manner, similar to that of other exopolysaccharide biosynthetic pathways. It is highly possible that the yjbEFGH operon encodes a system involved in EPS secretion since none of the products is predicted to have enzymic activity, the products are all secreted and YbjH and F are predicted to be beta-barrel lipoproteins similar to porins. It may be that the operon products play some role in biofilm formation and/or matrix production.	0
NC_008750.1\|WP_011788829.1\|1681566_1683282_-\|proline--tRNA-ligase	gnl\|CDD\|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
NC_008750.1\|WP_011788827.1\|1679564_1679816_-\|hypothetical-protein	gnl\|CDD\|374895	pfam16940, Tic110, Chloroplast envelope transporter. Tic110 is a family of chloroplast envelope proteins. Some are involved in protein translocation and others are neurotransmitter receptor, cys loop, ligand-gated ion channel or LIC proteins.	0.00486456
NC_008750.1\|WP_011788812.1\|1660208_1660769_+\|acyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	8.47454e-26
NC_008750.1\|WP_011788813.1\|1660804_1661419_+\|CatB-related-O-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	4.83292e-69
NC_008750.1\|WP_011788826.1\|1678706_1679417_-\|YjbF-family-lipoprotein	gnl\|CDD\|378557	pfam11102, YjbF, Group 4 capsule polysaccharide lipoprotein gfcB, YjbF. This family includes lipoprotein GfcB (YmcC), involved in group 4 capsule polysaccharide formation. YjbF is a family of Gram-negative bacterial outer-membrane lipoproteins, predicted to be a beta-barrel and possibly a porin that is one of four gene-products expressed from an operon, yjbEFGH, which is regulated by the Rcs phosphorelay in a RcsA-dependent manner, similar to that of other exopolysaccharide biosynthetic pathways. It is highly possible that the yjbEFGH operon encodes a system involved in EPS secretion since none of the products is predicted to have enzymic activity, the products are all secreted and YbjF and H are predicted to be beta-barrel lipoproteins similar to porins. It may be that the operon products play some role in biofilm formation and/or matrix production.	1.04004e-74
NC_008750.1\|WP_011788825.1\|1677912_1678698_-\|hypothetical-protein	gnl\|CDD\|368817	pfam06251, Caps_synth_GfcC, Capsule biosynthesis GfcC. Many bacteria are covered in a layer of surface-associated polysaccharide called the capsule. These capsules can be divided into four groups depending upon the organisation of genes responsible for capsule assembly, the assembly pathway and regulation. This family plays a role in group 4 capsule biosynthesis. These proteins have a beta-grasp fold. Two beta-grasp domains, D2 and D3, are arranged in tandem. There is a C-terminal amphipathic helix which packs against D3. A helical hairpin insert in D2 binds to D3 and constrains its position, a conserved arginine residue at the end of this hairpin is essential for structural integrity.	2.64272e-57
NC_008750.1\|WP_011788821.1\|1671444_1671891_-\|copper-resistance-protein-NlpE	gnl\|CDD\|377235	pfam04170, NlpE, NlpE N-terminal domain. This family represents a bacterial outer membrane lipoprotein that is necessary for signalling by the Cpx pathway. This pathway responds to cell envelope disturbances and increases the expression of periplasmic protein folding and degradation factors. While the molecular function of the NlpE protein is unknown, it may be involved in detecting bacterial adhesion to abiotic surfaces. In Escherichia coli and Salmonella typhi, NlpE is also known to confer copper tolerance in copper-sensitive strains of Escherichia coli, and may be involved in copper efflux and delivery of copper to copper-dependent enzymes.	1.15953e-36
NC_008750.1\|WP_011788817.1\|1664546_1664855_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198395	cd10448, GIY-YIG_unchar_3, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	2.01907e-51
NC_008750.1\|WP_011788811.1\|1659094_1660204_+\|DegT/DnrJ/EryC1/StrS-family-aminotransferase	gnl\|CDD\|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	6.12781e-143
NC_008750.1\|WP_011788822.1\|1672264_1673614_+\|GAF-domain-containing-sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	4.0787e-33
NC_008750.1\|WP_011788819.1\|1668547_1669621_+\|UDP-N-acetylglucosamine--undecaprenyl-phosphate-N-acetylglucosaminephosphotransferase	gnl\|CDD\|131433	TIGR02380, ECA_wecA, undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase. Members of this family are the WecA enzyme of enterobacterial common antigen biosynthesis, undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase. This family represents one narrow clade, and closely related sequences outside this clade may represent enzymes that catalyze the same specific reaction, but in the context of different pathways. A His-rich motif in a cytosolic loop of this integral membrane protein, shown critical to enzymatic activity for WecA is variously present or absent in the clade that includes Bacillus subtilis TagO teichoic acid biosynthesis enzyme, which may catalyze the same reaction as WecA. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides].	2.06645e-163
NC_008750.1\|WP_011788818.1\|1667283_1667820_+\|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl\|CDD\|380337	cd00438, cupin_RmlC, RmlC carbohydrate epimerase, involved in dTDP-L-rhamnose production. RmlC (deoxythymidine diphosphate (dTDP)-4-keto-6-deoxy-D-hexulose 3, 5-epimerase or dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; also known as RfbC) is a carbohydrate epimerase involved in the production of dTDP-L-rhamnose, a precursor of the bacterial cell wall constituent, L-rhamnose. L-Rhamnose (6-deoxy-l-mannose) plays an important role in the cell-wall structure of many bacterial species. It has been found to contribute to the virulence of several species, including the Gram-negative Salmonella enterica and Vibrio cholerae, where it is present as a part of the O-antigen, and is essential for the growth of Gram-positive bacteria such as Streptococcus pyogenes. RmlC converts dTDP-6-deoxy-D-xylo-4-hexulose to dTDP-6-deoxy-L-xylo-hexulose by catalyzing the epimerization of the 5-methyl and 3-hydroxyl groups of hexulose, the third of four steps in the dTDP-L-rhamnose biosynthetic pathway. RmlC belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.35679e-88
NC_008750.1\|WP_011788823.1\|1674396_1674699_+\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198395	cd10448, GIY-YIG_unchar_3, GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC.	8.93388e-52
NC_008750.1\|WP_011788815.1\|1662510_1663761_-\|IS4-like-element-IS10A-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	7.04672e-13
NC_008750.1\|WP_083758260.1\|1663816_1664164_+\|hypothetical-protein	gnl\|CDD\|224013	COG1088, RfbB, dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane].	9.12512e-45
NC_008750.1\|WP_011788830.1\|1683495_1684125_-\|acyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	1.25932e-43

>NC_008750.1|WP_011788819.1|1668547_1669621_+|UDP-N-acetylglucosamine--undecaprenyl-phosphate-N-acetylglucosaminephosphotransferase
MSTNIAVLFVFLVSFISLFVFRKVAQRIGLVDKPNERKHHKGQIPLVGGISIFFTIILALFLTPELLLAPQLYAGCAFILVVIGAIDDRYDISFKFRLVVQAAVSMLMIVLGERSLHNLGYLMGSEAIHLPEPISILLTVFAVIGAINAFNMVDGIDGLLGGLASVTFGGLGILFYFNGMQGFAIFCVLLVTAMLPYIMLNLGFPFGRRFKVFMGDAGSIFIGFTVIWLLIVASQGDRATALRPVTALWLIALPLMDMVCIMIRRIRKGQSPFKPDREHLHHICQRMGLSSHSSLMVICTAAAIMVAVGIWSELAKIDENIMFLAFLATFALYFGLINNIWRITAFWRKDIKISKSI
>NC_008750.1|WP_011788818.1|1667283_1667820_+|dTDP-4-dehydrorhamnose-3,5-epimerase
MKCIETELAEVLVFEPQRFGDERGFFMETFRQSYFDACFTERGFSLPIFVQENHSRSQQNVLRGLHFQRLQPQGKLVRVCTGSIFDVAVDIRANSPTYGQWVGRVLSADNRLQMWTPPGFAHGFYVLSEFADVIYRCTDYYAPHDEYVLGWNNTDFSIDWPLIAEPLLSDRDAIAART
>NC_008750.1|WP_041408137.1|1665408_1665645_+|hypothetical-protein
MREDDGKGENYALSVIPAKAGIHSKVFCYLKYKANYLTADPRVREDDDEGENYALSVIPAKAGIHSKVFYYLEYKVRT
>NC_008750.1|WP_011788817.1|1664546_1664855_+|GIY-YIG-nuclease-family-protein
MQPYVYIMASQFNGTLYIGVTSQLEQRVWQHKNAIIDGFTHKYKVDQLVYFEAHVSMYDAICREKQLKKWRREWKIDLINSQNPKWQDLWYTVIAGSPHTRG
>NC_008750.1|WP_083758260.1|1663816_1664164_+|hypothetical-protein
MLQVRALFLVATQGRLGQTYNIGGSNERSNIEVVQKICDLLEELAPTHPHAFAVNGIGFRGLIQHVEDRPGYDVRYAIDASKLEHELGWQPYESFESGLRKTVKWIVEQSDEVRS
>NC_008750.1|WP_011788815.1|1662510_1663761_-|IS4-like-element-IS10A-family-transposase
MIKWFLQKLHLDNKMREANILQHSLHQYCPELHLKRLNSLMLASKALIECKTLTLTELGRNLPTTARTKHNIKRIDRLLGNTHLHQERLAVYQWHASLICSGNPMPIVLVDWSDIREHKRIMALRASIAFNGRSITLYEKSYPLSEQCSKASHNGFLADLAKILPLHVTPLIVTDAGFKVPWYKEVEAHGWFWLSRIRGTVQFADIGAENWRAVRSTHDLANGQAKSLGCKTLTKTNPINCHLTLYRSKPKGRTNQRSTRTNCHHPSAKTYSTSAKEPWVLASNLPPESRSPKQLVNLYAKRMQIEETFRDLKSPAYGFGLRQSRTNSPERFDIILLIALMVQCLLWLVGLHAQQQGWDKHFQANTIGHRTVLSTIRLGLEVLRRPDYQITEKELLAAWVLFANQLLKYGYAMADL
>NC_008750.1|WP_011788814.1|1661411_1662359_+|glycosyltransferase
MNNSMVTVCIVTYNQKKYIEQCLDSIVNQKTDYSYQVIISDDASTDGTSEICAEYAKRYQFINHIRHATNIGAYENFKYVHRQAKTQYVSHCDADDSWHEDKLEKQIKFLEGNSDCCAVYSNAIVINEHGTRIGVFNNSEEIPSKITIGYLLEKSNFLNNSSMIYRRDMIGDIFDADGKVVDYRIHIHLANCGLLGYIKESLAFYRKGAAGGLCLNAPAAVGQLVHEARLDGIKNAKLSIVDFSKIKTNAWYGKLTCFLKRNKFMYARHTEVEALIVDYDFIQSVMFLFFEIVIYFFCKMKEKLSINKNIILYHR
>NC_008750.1|WP_011788813.1|1660804_1661419_+|CatB-related-O-acetyltransferase
MFFYLLKMFKVKFFSSRNQRLNDRITTIRGEGTYGPEPKLIGPHNVVEQLHFGSSIGKYCSIAAGIKFLFRGKHNTNWVSTYPFQVMMGLDVPLNDLTLHAPVKIGNDVWIATNVKIMQGVTIGDGAIIAQESLVTKDVPPYAIVGGNPARIIRYRFEPDEIQELLNLQWWNLPKNKIVLIAKYLTSQDVNECIKQIKMVKDNE
>NC_008750.1|WP_011788812.1|1660208_1660769_+|acyltransferase
MAFLTEQQLNSMGFAALGYNVFISDKASIYGVSRIRIGNNVRIDDFCVLSAGEGGIEIGNYIHIAVYSSLIGAGKITLSDFSNISSKVAIYSSNDDYSGEYMTNPMVPAKYTNVIHADVTIGKHVIIGSGSVVLPGVTLFAGAAIGSLSLVTKDCEAFGVYIGSPARKIKNRKRELLAVENNFIEK
>NC_008750.1|WP_011788811.1|1659094_1660204_+|DegT/DnrJ/EryC1/StrS-family-aminotransferase
MSNKNIPVTQPFLPELNEFIPYLEQIWDNRWLTNNGPFHQQLEAKLCEYLGVEHISLFNNATIALITALQSLRVTGEVITTPYSFVATSHSIMWNGLEPVFVDVDPTTFNIDPAKIEAAITPRTTAIMPVHCYSNPCDVEAIQNIADNYGLKVIYDAAHAFGVNYKGESLLKWGDLSILSFHATKVFNTFEGGAIISPDAKTKQRIDRLKNFGIADELTVTAPGINGKMSEINAAFGLVQLKHIDNAMAQRRAVDVRYREALADVTGITLYKHDSNANSNFSYFPILVEADYPLSRDELYDKLKNNHILSRRYFYPLISNMPMYRGLPSAAISYLPQANQLADKVLCLPIFNELTVDEQQQVIELIKGN
>NC_008750.1|WP_011788821.1|1671444_1671891_-|copper-resistance-protein-NlpE
MKQSLLGIALLALFTTACTDPAPKPTDTTPAQTESAANTPTGDTSQNSLDWPGNYEGVLPCASCEGIETHISLKADNSFELKSIYLGKDEKIFKVTGTAVWDAQGQKITLADGTQYLVGENQLIMLDTEGKRITGELAANYVLKKKSE
>NC_008750.1|WP_011788822.1|1672264_1673614_+|GAF-domain-containing-sensor-histidine-kinase
MTRMFDRILFDVSQSPLIDKGDLTVAAQLIVSSVCKGLNVKRVGIWLLSEDRQSISCFYLSHHPQLEQTLTLARVQYPHYFDLLDTERTIVLDHRQLDFTTQELASTYFNANNITAILASPIRHDGKMVGIICVEHQGEPREWMPDDKAFVSTLAEIFARSISARDILDYQRQLKVVNADLELRTQELEAALAHLSATQNHLIEKEKMAALGSLVAGVAHEVNTPLGIAVTSVTHCLDELALLKRFFESNELDQEKFLNFMTTMQDGLSLVDRNLARAAELVHNFKRTAADQSIWERERFNLKAYILQVFSSLKPLMRKKSISLTINVDDGIYLYSYPGAIAQIFTNLVSNSFRHGFPDNFTGEKQIIVEADKTSSTINIIYQDSGVGMSDDIKARAFEPFFTTAKQSGGTGLGMSIIHNLVTQKLNGRISLISAPNQGVKIEMQLPEE
>NC_008750.1|WP_011788823.1|1674396_1674699_+|GIY-YIG-nuclease-family-protein
MQPYVYIMASQFNGTLYIGVTSHLEQRIWQHKNAIVDGFTHKYKVDQLVYFEVHASMYDAICREKQLKKWRREWKINLINSQNPKWEDLWYTVIVGSPHR
>NC_008750.1|WP_011788824.1|1675546_1677913_-|YjbH-domain-containing-protein
MKKPSHSIHTLGRLSALSLALLPLLHASADEFAYPTLLPSQSDFGGVGLMQMPTGRMAAEGEFNFSTTYNDEYQHYTASVQLFPWFETTVRYTLVHDLLYSNDPNFSGNTKYTDKGIDFKVRLLEESYWLPETSIGVRDFGGTGLFDGEFIAATKRVGPLDFTLGIGWGYIGNSGNLTSDKKDLNYNCDRDTSYGGKGGEVDYQRWFKGCAALFGGVEYQTPWDPLRVKVEYDANDYESDFPVVRGGIDMTQDSKFNYGLLYRFGNWGDLHLSYERGNTWTLGFSLQTNFNTLTQIKRDPAAAKYKPLPAAPMTQAQLAQTEDTPSSVASIDTASYQESNTDNIQADTALNVDSTVNTASLSTAATETTDWNKVAQDLQRIAGYNNAKIYLAADRITVVGEQTKFRDRSEAHHRTATILANNSALSQIKEYRLIETHYSQPITETRIDAEKFAKVANFAYLNAKVSDASQVSVPSAPQGTLVTQTNTDWLDKLGFDVSPTMVQSFGGSEGFYMFNIGVTGSANYKFTDNFEFGGSLYLNLYDNYDKFLYDVPPDGTDLKRVRTLIRQYVHDNPVRMNNLQLTWMDNLSDNVSYQAYGGYLEMMYGGVGTEFMYRPLNSQWAFGIDVNYVKQRDPDNMFGFFKDEHQFDPLIGRAYRVQTGAMTGHATVYYQPEWFPNTLLRVSAGQYLTEDKGVTVDLSKQFDSGVIVGAFATKTNLSADEYGEGSFTKGFYISVPFDLMTIKSTHSRAFLSWIPLTRDGGQMLGRKYNLFDVTDARAPWYTKPSTEK
>NC_008750.1|WP_011788825.1|1677912_1678698_-|hypothetical-protein
MKSYLTPLALLVSSVFSTVAHAETQLFVTTSSTLDAPLHIVYPTGIRIGQAVQDGLQQLPLYNKTNNKEVMPIYWLGAALVDLENTAVLETKRQQVLSQLAQMGEATNDSRYITKLAQLAQFLRGIKLGQRVMQPLDIDAIRITESYNAIIEGKYQLVLPPRPSTITLVGAVSQTGNMPWQSQASSKDYLQQAGLLENAETSFVWIIQPDGNAIRQPIAYWNYQAQDIAPGATLFVEFSSLFDGYANLNENIIELLKNRTL
>NC_008750.1|WP_011788826.1|1678706_1679417_-|YjbF-family-lipoprotein
MRINKNLVRLLTISTVLMGITGCSQRISALNDTIKLAFLGEDDVKLTSEQVKSNPYASIYAKIGDTPQAFVVLAFAEPKVTLSNVRPEPDSTELKWLSADNGMLVTINGRLIKTHNLLEGNLAAVESHEPDPIVLGLHLDNTPKTWTRTLDWQPGYHYGYKVTSQFKLIADENVLINDTPTQLLHYSETVSVEGLNIQYQNDFWLKPDNGHVVKSRQKIAPNLPFIDIILLKPFAS
>NC_008750.1|WP_011788827.1|1679564_1679816_-|hypothetical-protein
MKKTSLALVTALTMFASVSVNAAETETGTATGGATTGGAVGGLAAGAIAAGAVVAGVVVASNGSDGNPITSTGTTTTSNSGAN
>NC_008750.1|WP_011788828.1|1680299_1681424_+|patatin-like-phospholipase-family-protein
MPTSTALVLGGGGARAAYQVGVLKALVQLYPRNHGIPFKIICGTSAGAINGTAIATHASCFHLGVRKLEWVWRHFETRKVYRASIFGVLSHLAKMALKGMQDDKVNTDAGSLLDNDPLRKLLNELIDFKRIDRNIRSGSLTALSVDTSCYNNSRSVTFFQASRDIDNWTRARRSGQRMMLNTEHLLASSAIPMVFPSIKLNQAYYGDGSVHQLAPLSSPIHLGAKKLLVINLDSPHKHFPMELEYHPKTATIAGHLLDTIFSDTLNSDLERLERINNTLAQIPEESRKKLTLQPIKTLVIKPSEDLSKLAARFYDDMPWAIRVLLGFTGINRQSDSSIVSYLLFEKSYTSALIDLGYKDAMEQMNELKAFFDLN
>NC_008750.1|WP_011788829.1|1681566_1683282_-|proline--tRNA-ligase
MRVSKYLLSTQKETPANAEVISHQLMLRAGMIRRNASGLYSYLPTGLRVLRKVEAIVREEMNKAGAIEILMPMVQPADLWVETGRWDKFGPELLRFKDRHNRDFVLGPTHEEVITDLIRKEVSSYKQLPLNLYQIQTKFRDEVRPRFGMMRSREFLMKDAYSFHLDVDTMNETYEAMYTAYSNILSRMGLAFRPVLADTGSIGGSMSHEFHVLAQSGEDLIAYSTGSDYAANIEKAESPMPTEPRGAATEALRLVDTPNAKTIAELVEQFDLDITKTVKTLIVKGATEAAPLVALIVRGDHELNEVKADKLDLVASPLEMAPEALIRDAIGAGPGSLGPVGLNMPIIIDHSVSVMSDFAAGANVDDKHYFGINWERDLPLAQAADIRNVVEGEPTPDGLGTYAMARGIEVGHIFQLGTNYSKSMNATVLDENGKSQVLLMGCYGVGVSRIVAAAIEQNFDDRGIVWPEAIAPFSVGILPMNMHKSHRVTDIAEQLYKDLSAAGIEVLLDDRKERPGVMFADMELIGIPHTVVIGDRNIDAGVFEYKNRRTGEKQDIPFDQLVDFLKNAVKS
>NC_008750.1|WP_011788830.1|1683495_1684125_-|acyltransferase
MSAPTPTSKPDYQSQHKKRLSWMPWLYFSLKEKHLVWAKPWQDQVQAALCALETVTIGDNCFIAPEAQLFAEPNRDINIGDRCMIAAECFLHGPITLGNEVAINHGCSFDGGRVGIQIGDQTRIANNVTIYAFNHGMAPDTPIYQQAANSKGIVIGKDVWIGAQAGIVDGVTIGDHAVVGMGSIVTKNVPNWAIVAGNPARVIGDRRDK

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Crispr_ID: NC_008750_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008750_3

2342397-2342501

Orphan

Consensus_repeat	Method
GCTGCGCCGCTAGGACGCAGCGAATTGTGTGCAGAGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008750_3

>merge|NC_008750|3|2342397-2342501|CRISPRCasFinder
GCTGCGCCGCTAGGACGCAGCGAATTGTGTGCAGAGGGTCACGATCGAATTCAGAACTTAATTGAACGGCTGCGCCGCTAGGGCGCAGCGAATTGTGTGCAGAGG

>NC_008750|3|3|2342397-2342501|CRISPRCasFinder
GCTGCGCCGCTAGGACGCAGCGAATTGTGTGCAGAGG	GTCACGATCGAATTCAGAACTTAATTGAACG
GCTGCGCCGCTAGGGCGCAGCGAATTGTGTGCAGAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008750.1\|WP_157037389.1\|2349544_2349742_-\|hypothetical-protein	unknown	unknown	unknown
NC_008750.1\|WP_008983536.1\|2337458_2338709_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271180
NC_008750.1\|WP_008983529.1\|2343672_2344257_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_008750.1\|WP_011789345.1\|2354386_2354776_+\|RidA-family-protein	unknown	unknown	gnl\|CDD\|100005
NC_008750.1\|WP_011789337.1\|2336161_2336842_-\|hypothetical-protein	unknown	unknown	unknown
NC_008750.1\|WP_008983541.1\|2332042_2332663_-\|hypothetical-protein	unknown	unknown	unknown
NC_008750.1\|WP_008983530.1\|2342514_2343597_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381317
NC_008750.1\|WP_008983532.1\|2341365_2341851_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NC_008750.1\|WP_011789339.1\|2339786_2340959_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|378704
NC_008750.1\|WP_011789344.1\|2353608_2354196_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_008750.1\|WP_008983539.1\|2333043_2336019_-\|Tn3-family-transposase	unknown	unknown	gnl\|CDD\|376561
NC_008750.1\|WP_008983531.1\|2341847_2342339_+\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NC_008750.1\|WP_008983528.1\|2344301_2344970_-\|cupin	unknown	unknown	gnl\|CDD\|380437
NC_008750.1\|WP_008983526.1\|2345887_2346439_+\|acyloxyacyl-hydrolase	unknown	unknown	gnl\|CDD\|378181
NC_008750.1\|WP_008983537.1\|2336903_2337449_-\|hypothetical-protein	unknown	unknown	unknown
NC_008750.1\|WP_040291339.1\|2339243_2339519_-\|DUF1778-domain-containing-protein	unknown	unknown	gnl\|CDD\|370057
NC_008750.1\|WP_011789343.1\|2351875_2353504_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NC_008750.1\|WP_008983527.1\|2345017_2345638_-\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|198291
NC_008750.1\|WP_008983535.1\|2338724_2339243_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_008750.1\|WP_011789342.1\|2350982_2351744_+\|IS5-like-element-ISSpu10-family-transposase	unknown	unknown	gnl\|CDD\|379129

Protein	Function_ID	Function_description	E-value
NC_008750.1\|WP_008983536.1\|2337458_2338709_-\|site-specific-integrase	gnl\|CDD\|271180	cd00799, INT_Cre_C, C-terminal catalytic domain of Cre recombinase (also called integrase). Cre-like recombinases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The bacteriophage P1 Cre recombinase maintains the circular phage replicon in a monomeric state by catalyzing a site-specific recombination between two loxP sites. The catalytic core domain of Cre recombinase is linked to a more divergent helical N-terminal domain, which interacts primarily with the DNA major groove proximal to the crossover region.	4.98693e-49
NC_008750.1\|WP_008983529.1\|2343672_2344257_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.98946e-08
NC_008750.1\|WP_011789345.1\|2354386_2354776_+\|RidA-family-protein	gnl\|CDD\|100005	cd02198, YjgH_like, YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	9.27578e-56
NC_008750.1\|WP_008983532.1\|2341365_2341851_+\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	4.55407e-20
NC_008750.1\|WP_008983530.1\|2342514_2343597_-\|aldo/keto-reductase	gnl\|CDD\|381317	cd19091, AKR_PsAKR, Polaromonas Sp. aldo-keto reductase and similar proteins. The prototype of this family is an uncharacterized aldo-keto reductase from Polaromonas sp.	5.23287e-176
NC_008750.1\|WP_008983528.1\|2344301_2344970_-\|cupin	gnl\|CDD\|380437	cd20303, cupin_ChrR_1, Marinobacter hydrocarbonoclasticus anti-ECFsigma factor ChrR, and similar proteins; 2 heterologous tandem repeats of cupin domain. This family contains bacterial anti-sigma factor such as ChrR from Marinobacter hydrocarbonoclasticus. Anti-sigma factor ChrR is a member of the ZAS (Zn2+ anti-sigma) subfamily of group IV anti-sigmas. It inhibits transcriptional activity by binding to the ECF sigma factor E (sigmaE), an essential factor to mount a transcriptional response to a singlet oxygen and for viability when carotenoids are limiting. This protein family likely contains two distinct homologous functional domains belonging to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	2.56175e-54
NC_008750.1\|WP_011789339.1\|2339786_2340959_+\|DNA-binding-protein	gnl\|CDD\|378704	pfam11740, KfrA_N, Plasmid replication region DNA-binding N-term. The broad host-range plasmid RK2 is able to replicate in and be inherited in a stable manner in diverse Gram-negative bacterial species. It encodes a number of co-ordinately regulated operons including a central control korF1 operon that represses the kfrA operon. The KfrA polypeptide is a site-specific DNA-binding protein whose operator overlaps the kfrA promoter. The N-terminus, containing an helix-turn-helix motif, is essential for function. Downstream from this family is an extended coiled-coil domain containing a heptad repeat segment which is probably responsible for formation of multimers, and may provide an example of a bridge to host structures required for plasmid partitioning.	8.83038e-13
NC_008750.1\|WP_011789344.1\|2353608_2354196_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.34316e-15
NC_008750.1\|WP_008983539.1\|2333043_2336019_-\|Tn3-family-transposase	gnl\|CDD\|376561	pfam01526, DDE_Tnp_Tn3, Tn3 transposase DDE domain. This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, Tn3926 transposons from E-coli. The specific binding of the Tn3 transposase to DNA has been demonstrated. Sequence analysis has suggested that the invariant triad of Asp689, Asp765, Glu895 (numbering as in Tn3) may correspond to the D-D-35-E motif previously implicated in the catalysis of numerous transposases.	0
NC_008750.1\|WP_008983531.1\|2341847_2342339_+\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	5.05776e-15
NC_008750.1\|WP_008983526.1\|2345887_2346439_+\|acyloxyacyl-hydrolase	gnl\|CDD\|378181	pfam09411, PagL, Lipid A 3-O-deacylase (PagL). PagL is an outer membrane protein with lipid A 3-O-deacylase activity. It forms an 8 stranded beta barrel structure.	1.80178e-26
NC_008750.1\|WP_040291339.1\|2339243_2339519_-\|DUF1778-domain-containing-protein	gnl\|CDD\|370057	pfam08681, DUF1778, Protein of unknown function (DUF1778). This is a family of uncharacterized proteins. The structure of one of the hypothetical proteins in this family has been solved and it forms a helix structure which may form interactions with DNA.	4.53061e-15
NC_008750.1\|WP_011789343.1\|2351875_2353504_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	4.26193e-58
NC_008750.1\|WP_008983527.1\|2345017_2345638_-\|glutathione-S-transferase	gnl\|CDD\|198291	cd03182, GST_C_GTT2_like, C-terminal, alpha helical domain of GTT2-like Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, Saccharomyces cerevisiae GTT2-like subfamily; composed of predominantly uncharacterized proteins with similarity to the Saccharomyces cerevisiae GST protein, GTT2. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain. GTT2, a homodimer, exhibits GST activity with standard substrates. Strains with deleted GTT2 genes are viable but exhibit increased sensitivity to heat shock.	1.49699e-41
NC_008750.1\|WP_008983535.1\|2338724_2339243_-\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	0.00873894
NC_008750.1\|WP_011789342.1\|2350982_2351744_+\|IS5-like-element-ISSpu10-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.07755e-23

>NC_008750.1|WP_008983531.1|2341847_2342339_+|PaaI-family-thioesterase
MSKTDDLAQQRSRAAESREKCADWKALLERIPYAQHLGLQVQCGDAVVLVYLPCNETLIGNFMLPALHGGVVGALIELTARVAAQSKDRDKRCPRIIDSHVNYLRSAKAQSTFASAEIVRQGRRSSLVSVTCWQNDKSKPIASGQVQLLLPTIAAEQEELHDS
>NC_008750.1|WP_008983532.1|2341365_2341851_+|PaaI-family-thioesterase
MNELSRLQHSHVVTAACQFTEQVPHARALGIQVVSVDRDQVRMRLTPQSWMFAQEDTKEICTSLLYSLADSAGGLAVIAGAMELMPIATLDLRMDYLRPANGDRALLAVATCRHLTDQVAFIDCDIFCEADSELLATAKATFMRNTHGQQFHSDGLKKNSV
>NC_008750.1|WP_011789339.1|2339786_2340959_+|DNA-binding-protein
MARDGITKHQVQQVRNELIAQGRHPSVELVRSELGSGSNTTILKYLRELEVDEKGRLDNLSALSDELGQFVGHLAQRLQEEAMQRIKTTEERHHLVIAERQRQLDVLRQELMAISEHRDKLEHQHREALAQIEELKHARHEDALQLSSMTSENRHLSGTIQDKEKHIQSLEEKHTHARHALEHYRESVKTQREQEQHRHDHQVQQLQAELRLSHQALSVKQQECTTLKEQTQQQSAELHHATQSVSKIEQQLLGSQNSQQQTEQQLYRKDTELNRLQKQHEDLQQQYAAAAAKVASLQANEQAWLQEKAALSASLSTQQQLWQTFSTVNAISTPAQYAKGEDVIVVDADHALYDRIGQVERCVKKGSTVKYSVNFDGETYTLPDRILRLA
>NC_008750.1|WP_040291339.1|2339243_2339519_-|DUF1778-domain-containing-protein
MTTVLRERIEMRVDAETKQLAERAAAASGCASLTEFMVRLIRDNAPQILQAQAAIELTSAQFDQFMQVCEAPPTPHARLKAAAARLDHEGF
>NC_008750.1|WP_008983535.1|2338724_2339243_-|N-acetyltransferase
MALAAEFVLLDAALHDLKGFDCGKASLNDYLSRYAVRNSGLGLSRTWVLTEQAEHGKLPIAAYYTLASSTVAREELPAQNKSLPTYPVPVVLLARLGVSVHYQGQQLGAKTLVQALRTALELADRGLPALGVVLDVLDDATLRFYQHMGMFMPLTDQPQRLFVPMGTIRQLS
>NC_008750.1|WP_008983536.1|2337458_2338709_-|site-specific-integrase
MSKVDRYLQAATREHTRRSYQSAVEHFEVAWGGVLPTTATELARYLAHYADTLAITTLKQRLAALSSWHQAQGFADPTKAPLVRQVLKGIRELHPDKAKQAKPLQLNVLEQIIGYLDQQALQAQQTENYAKHLRAVRDKALVLMGFWRAFRSDELSRLHIEHLEFVPNEGMIAYLPRSKTDRTNQGQAFRLPELQRLCPVDACRQYLVLLQQAAGPLFRAVNRWGMVSESSLRADSIIPLLRHLLQQAQVGDAALYSSHSLRRGFANWANQQGWSLKQLMEHVGWRDVKSAMRYLESNDPFSQQAIDQALALPAPSQVQNQLKTHVLELRLHLQPYHQRGRSSAARQHIERYCLKPYAMSKGSQQESYLLTMQARDHEELDGIVDDLLLQLHDAARAHQCMVEITLKEQATGQQWD
>NC_008750.1|WP_008983537.1|2336903_2337449_-|hypothetical-protein
MDWMDAGKVGLSSAAFGISCLALWISHRNWLRSNCPIVVACIETATAQDEAFIAYNLVVVNTGNRPAVNVRLYCEDSDLEQCIQPGPHAGKKPGSTWTHVKKCFQEDAEIPVLLNGKSVSNSFGFTGVNQQSFWKYNSRLKITLRYADLDGTNYRKELILLIKDSVAFAGGMWSMPEETKK
>NC_008750.1|WP_011789337.1|2336161_2336842_-|hypothetical-protein
MTDPDTTQKSQVLCKHCCHPIPHGARICSICRSYQNWFSFIPFSSTILALLTALISVMGIVIPLLYGIFHTPQSEASLTMPSIDGTTLRVTAVNTGDASASLIRAWFSSDLLAGATKVKLRNDDDALLPPGHKLLVFDIIPLLDEQGSYQHSLEMMSYITQNKPGPSTKIRFHVLQSDGRFAIQEFALSADDLFKLFRANADRCSAIEKVNFENGCIGAGVPAEEP
>NC_008750.1|WP_008983539.1|2333043_2336019_-|Tn3-family-transposase
MATVAQTAYPTLPANFSLKLLNKQYQPTNYELEWLSAIRKPIQRLGFLVQLKTLQRLGYVVSPLDCPDTLIKYLAKLTGITTLPSAKDWAAYIKSTARTKHLAQIREFVGVKLLQEADWAWLKTVARRAALVKDAVNDILNVSLEELIHHRFELPGFTRLLRLARTARNEVNTEYYRAIYDELRPESIAELDQLLIKDVNESYSAWQRLKREPKKPSAREIRSYIQHVTWLKSLSEQMPQIRLPATKLSQFMLEARALDAKDMRELKPLKRYALAVLLIRGQHGKALDDVADIMIRILRGLESVAKKNYDQHILNRQKESEALVRGYFDAMAAFGSEGTAEERIDAIQKTFSPDLTTQMAKCQEYLAAVAHGFLPFMLQPYHQKRSLLFLCLEAMELRSTSTDQSTISLIANLQSLRNSHKEMLPVSQLQSDEFDLLTLLSPQWQNIIRRDVAGNALYHRKLYELACFSMIRRELQSGDLHVVHAREYDDYREDLVSWEEYQQEIDRYAQEVEQPVNDAERFVTELQLELSELATTVDLTFPGNSHAQFIDGRLSLKKSNTARPVAAVQRLDTAIVDGMEPSSIVDILTDCEHWLELHKLIHTAAGNQVKIEFPEQRFLTTLFCYGCNLGPAQTSRSVKGFTQKQVAWLNLRHVTEERLEKALTKVVNAYNQFDLPKYWGSGKHASADGTKWELYEQNLMSEFHIRYGGYGGIGYYHVSDTYIALFSHFIPCGTYEGVHILDIVQKNDSDIQPDTLHGDTQSQSYTVFGLAHLLGIKLMPRIRNIQDLSLYRPSKDTKYQHIDALFKGSIDFDLIQARLPDMLRVVVSIKLGRITPSTLLKRLGTFSRKNKLYFAFRELGRLIRTMFLLNYIDNHELRQLIHAETNKSEAFNNFTKWLFFGNDGIIAENIRHEQQKIVKYNQLVANMVILYNTEKMTKLLKKLAEAGHEVTPETLAGLSPYRTSHINRYGDYHIDINRKTEPLDFTVKVIE
>NC_008750.1|WP_008983541.1|2332042_2332663_-|hypothetical-protein
MQSTGTDEELSYPTLPAFVTASIDQNTFNKAWFDAMTELPMSAQLKVAATAPDEKWNNELGLTSLNEAKIKYQGDVGTLKQTIFVELKGCIEAWADIEGQAIEPKIVAEMACYIMAIWQSDTFYLAFPTLRVLIALHGSLRTDPNRRFKSGDLNDFSVAADALSICDVFLTDRRLANLISSEELDLGTLLGCQVIHGFEAMANYFS
>NC_008750.1|WP_008983530.1|2342514_2343597_-|aldo/keto-reductase
MTTDKIPNFEQNHIRYKALGNSGLMVSELCLGTMTFGGDEDIWGLIGQLRQEQADELVRIALQAGINFIDTANIYGLGASELIVGQSLKNLGVRREDVVLATKVLGPMGEGPNARGASRGHIMNECKASLSRLQTDYIDLYQIHGFDPATPIEETLEALNTLVQQGYVRYVGLSNWAAWQVMKAIGISQARNLCPVTSLQAYYTLVGRDLEREVIPMLSSEKVGLMVWSPLAGGYLSGKYEGPDVSEENRRAKFDFPPVNRERGRDIIKVMREVADGKQIDGEPVSVAQIALAWLLHQESVSSIIVGAKRPEQLKANIRAAQIRFSDDERKALDEVSRIPEEYPGWMMEMMAGYRNPSKF
>NC_008750.1|WP_008983529.1|2343672_2344257_-|TetR/AcrR-family-transcriptional-regulator
MNRDTRTTLLDIAEYNARSRGFDGFSYADLAVAVGIRKASIHYHFPTKADLSDHLIARYHTSLKERLAEIENDHLSADERLMALIRLYREALNGGQTVCLCVAFSICRERISEKVVIRVGAVRAMLLKWIKCIFELGLKDRSISLITAPEEEACATLAMLEGAHLAARTAQDPASFDAAIQMLLGRCRQSARKE
>NC_008750.1|WP_008983528.1|2344301_2344970_-|cupin
MEINADITKPVVIDTDQLLWCPSPVKGVERRMLDRIGDEVARATSIVRYAPGSQFSAHTHVGGEEFIVLDGVFQDEHGDYPSGTYVRNPPTTSHVPCSAEGCTIFVKLWQFDPEDRNQFKKNMEAELNASVEGVATSLLHEDGREAVTFHKLDSGATLNSNAVGGIEMLILDGEVMINDDVLSKNAWLRLPEGEALSAKAGGLGAKIWMKTGHLRFVRAPEV
>NC_008750.1|WP_008983527.1|2345017_2345638_-|glutathione-S-transferase
MKIYETTGFPNPLRVRIALAEKGATNKVIFVPVDVMGGEHRTSAFKAKNPDATVPLLELDDGTCIAHCNAITEYLDGIFDGPSLTGTSPKERAVIAMMNIRAESGLMNAVGAYFHHATQGLGPDLETWQCPDWGSKQKEVAQLTMIYLDGVLTESDFVAGNRFTVADITAYAGLVFAEFAKVEIPENLRALKAWRDRVAARPSING
>NC_008750.1|WP_008983526.1|2345887_2346439_+|acyloxyacyl-hydrolase
MSKGFLALIVAMVFGFWGLMNSASAQADEWHMTGSYSTDQLRGARVGYRVTDIRLSILEDWTWLGSPKLHIEGALNNWQNSNDRSDNVFALTISPVLAWQLTDGPRPLYVEAGIGGSVLDGTRLGERRLSTRFQFEDRIGLSWQYSAYSNARLTLAYVHYSNADIDSPNDGLDFFGLTWSNTF
>NC_008750.1|WP_157037389.1|2349544_2349742_-|hypothetical-protein
MKSNKYLPAASTFLALLLWNPDKTISHIRKYGLFRAYKVGVSVGAINNAIDMALQNMAFLQLREE
>NC_008750.1|WP_011789342.1|2350982_2351744_+|IS5-like-element-ISSpu10-family-transposase
MPRTMLTDEYWSKLIRLMLKTGRVYDKPEHRNTFEGILYRMRVGCPWRDVPEAFGDWSAIYRRFNLWSKKGILMQLFAELRQLADLEWEFIDGSIVKAHQHATGARSEDKEAIGKSRGGNTTKIHMAVDSCGLPIDFIVTGGEVHDSKAAIELLKQLPDAEHVIADRGYDSEKIREQIREKKGVPNIPRKRNSKIGNGDIDWCLYKYRHLVENVFARLKHYRSVATRYDKLARNYASTLALACCLIWLPMWVG
>NC_008750.1|WP_011789343.1|2351875_2353504_+|methyl-accepting-chemotaxis-protein
MNVINRLYSGFAMLLLIMLGITLFGLFKISIADQNLTQLSEQTAVEQRQAINFRGSVHDRAISIRDAVLVKDTSASQIHQNDITRLNGFYQQSAATLDSMYSKIKHTPEEENLLRQIKEIESSTLAVTKNILDMINSGRQQEATDYLLTTVSPAYSEWLKRINKLIDFQEEAIQHQVASAREQTNSFQRIMLLVTAIAIVIGCVVAVSTVNRLKRMVGGEPEYAASVIKKIASGDLTVQVKSHTAESILSAVKDLTEHMSGITKNSIRAANELLTASKQLLETAQYNEDLIGNQKLATEQGATAINQMSSTVAEVANHTSDAAGLAQTAINEFNAGQAEVSKTQSSINALADKVSDAAEVINHLSEDSRQIGSVLEVIQGIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRNLARRTQDSTRQIQTVIEKMQGSSLKAVAVMNEGKAQAETSVEQAQRAGDSLNAINLSVTKISDMNTQIATAAEEQSVVASEINRNFSQITHSAVMAEEQASKITVASQQLEKLAKTLEQNVKQFKTA
>NC_008750.1|WP_011789344.1|2353608_2354196_-|TetR/AcrR-family-transcriptional-regulator
MSIRLTKMAENREKLIAAARRAFAEHGYAAASMDTLTAEAGLTRGALYHNFGDKRGLLAAVVDQIDSEMAEYAKSVGAKAENAWSGLLAEGAAYIEKALDPEVQRIVLLDGPSVLGDPSQWPSQNKCLQSTRSTIEKLIENGTVKPVDAEAAAMLLNGAALNAALWLASSAEPQAMLPKTLEAFNLLASGFLVKN
>NC_008750.1|WP_011789345.1|2354386_2354776_+|RidA-family-protein
MKREAIFPANRHALYEEHGYSAAIRSGDLLFVSGQVGSRADGSPEADFELQVELAFENLKATLAAAGCTFDDIVDVTTFHTDPEHQFGTIMKVKQKIFGAPPYPNWTAVGVTWLAGFDFEIKVIARIPG

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Crispr_ID: NC_008750_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008750_4

2460787-2460891

Orphan

Consensus_repeat	Method
AGGAAAACTATGAGTCACTTATTTGCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008750_4

>merge|NC_008750|4|2460787-2460891|CRISPRCasFinder
AGGAAAACTATGAGTCACTTATTTGCCCGCTTTTATAACACGAATGAAGCTTATCTAACGCTGGCCTTCGAATAAATAGGAAAACTATGAGTCACTTATTTGCCC

>NC_008750|4|4|2460787-2460891|CRISPRCasFinder
AGGAAAACTATGAGTCACTTATTTGCCC	GCTTTTATAACACGAATGAAGCTTATCTAACGCTGGCCTTCGAATAAAT
AGGAAAACTATGAGTCACTTATTTGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008750.1\|WP_011789426.1\|2452139_2452916_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|182637
NC_008750.1\|WP_041408186.1\|2463024_2463666_-\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	unknown	unknown	gnl\|CDD\|235577
NC_008750.1\|WP_011789429.1\|2453579_2454107_+\|flavodoxin-FldA	unknown	unknown	gnl\|CDD\|236439
NC_008750.1\|WP_011789436.1\|2461485_2462835_+\|deoxyguanosinetriphosphate-triphosphohydrolase-family-protein	unknown	unknown	gnl\|CDD\|235403
NC_008750.1\|WP_011789439.1\|2465536_2466235_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|238694
NC_008750.1\|WP_011789443.1\|2472166_2474446_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|237277
NC_008750.1\|WP_011789444.1\|2474458_2475100_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380065
NC_008750.1\|WP_011789441.1\|2468027_2468882_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|183082
NC_008750.1\|WP_011789430.1\|2454216_2455395_+\|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP	unknown	unknown	gnl\|CDD\|378385
NC_008750.1\|WP_011789428.1\|2453250_2453523_+\|LexA-regulated-protein	unknown	unknown	gnl\|CDD\|183272
NC_008750.1\|WP_011789434.1\|2459375_2460590_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|181738
NC_008750.1\|WP_011789442.1\|2469066_2470506_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NC_008750.1\|WP_011789425.1\|2451300_2451858_-\|replication-initiation-negative-regulator-SeqA	unknown	unknown	gnl\|CDD\|236874
NC_008750.1\|WP_041408385.1\|2463685_2465512_-\|phosphogluconate-dehydratase	unknown	unknown	gnl\|CDD\|181628
NC_008750.1\|WP_011789101.1\|2470673_2472047_+\|IS4-like-element-ISSpu9-family-transposase	unknown	unknown	gnl\|CDD\|373239
NC_008750.1\|WP_011789432.1\|2456171_2456993_-\|hypothetical-protein	unknown	unknown	unknown
NC_008750.1\|WP_011789433.1\|2457207_2458590_-\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|224671
NC_008750.1\|WP_011789440.1\|2466244_2467717_-\|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235579
NC_008750.1\|WP_011789427.1\|2453017_2453239_+\|DUF2788-domain-containing-protein	unknown	unknown	gnl\|CDD\|378526
NC_008750.1\|WP_011789431.1\|2455439_2456000_+\|elongation-factor-P	unknown	unknown	gnl\|CDD\|234788

Protein	Function_ID	Function_description	E-value
NC_008750.1\|WP_011789426.1\|2452139_2452916_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|182637	PRK10673, PRK10673, esterase.	9.40813e-78
NC_008750.1\|WP_041408186.1\|2463024_2463666_-\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	gnl\|CDD\|235577	PRK05718, PRK05718, keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; Provisional.	2.28109e-131
NC_008750.1\|WP_011789429.1\|2453579_2454107_+\|flavodoxin-FldA	gnl\|CDD\|236439	PRK09267, PRK09267, flavodoxin FldA; Validated.	8.59013e-107
NC_008750.1\|WP_011789436.1\|2461485_2462835_+\|deoxyguanosinetriphosphate-triphosphohydrolase-family-protein	gnl\|CDD\|235403	PRK05318, PRK05318, deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional.	0
NC_008750.1\|WP_011789439.1\|2465536_2466235_-\|6-phosphogluconolactonase	gnl\|CDD\|238694	cd01400, 6PGL, 6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.	6.08117e-79
NC_008750.1\|WP_011789443.1\|2472166_2474446_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|237277	PRK13026, PRK13026, acyl-CoA dehydrogenase; Reviewed.	0
NC_008750.1\|WP_011789441.1\|2468027_2468882_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|183082	PRK11302, PRK11302, DNA-binding transcriptional regulator HexR; Provisional.	0
NC_008750.1\|WP_011789430.1\|2454216_2455395_+\|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP	gnl\|CDD\|378385	pfam10093, EarP, Elongation-Factor P (EF-P) rhamnosyltransferase EarP. This entry includes family members such as EarP enzymes which are essential for post-translational activation of elongation factor P(EF-P). It was identified as EF-P arginine R32 specific rhamnosyl transferase in Shewanella oneidensis using dTDP-beta-L-rhamnose as donor substrate. This was further confirmed for Pseudomonas aeruginosa, Pseudomonas putida, and Neisseria meningitidis. As for S. oneidensis and P. aeruginosa, EarP enzyme acts as an inverting glycosyltransferase, thus mediating the formation of an alpha-L-rhamnosidic linkage. Structural analysis show that EarP is composed of two opposing domains with Rossmann folds, thus constituting a B pattern-type glycosyltransferase (GT-B) and provide basis for arginine glycosylation by EarP. Mutational analysis of efp and earP genes, resulted in a substantial decrease in the production of rhamnolipids and pyocyanin (important factors for colonization and invasion during infection) of P. aeruginosa. Collectively this indicates that EarP and EF-P are essential for P. aeruginosa pathogenicity.The protein family is also annotated in the CaZy Database as GT104.	0
NC_008750.1\|WP_011789428.1\|2453250_2453523_+\|LexA-regulated-protein	gnl\|CDD\|183272	PRK11675, PRK11675, LexA regulated protein; Provisional.	1.25319e-44
NC_008750.1\|WP_011789434.1\|2459375_2460590_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|181738	PRK09265, PRK09265, aminotransferase AlaT; Validated.	0
NC_008750.1\|WP_011789442.1\|2469066_2470506_+\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NC_008750.1\|WP_011789425.1\|2451300_2451858_-\|replication-initiation-negative-regulator-SeqA	gnl\|CDD\|236874	PRK11187, PRK11187, replication initiation negative regulator SeqA.	5.08991e-98
NC_008750.1\|WP_041408385.1\|2463685_2465512_-\|phosphogluconate-dehydratase	gnl\|CDD\|181628	PRK09054, PRK09054, phosphogluconate dehydratase; Validated.	0
NC_008750.1\|WP_011789101.1\|2470673_2472047_+\|IS4-like-element-ISSpu9-family-transposase	gnl\|CDD\|373239	pfam14706, Tnp_DNA_bind, Transposase DNA-binding. This domain occurs at the C-terminus of transposases including E. coli tnpA. TnpA encodes a transposase and an inhibitor protein, the inhibitor only differs from the transposase by the absence of the N-terminal 55 amino acids, which includes most of this domain. This domain consists of alpha helices and turns, and functions as a DNA-binding domain.	6.66141e-18
NC_008750.1\|WP_011789444.1\|2474458_2475100_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|380065	pfam17939, TetR_C_30, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in the Pseudomonas aeruginosa PsrA which regulates the fadBA5 beta-oxidation operon. Functional analysis of PsrA indicated its importance in regulating b-oxidative enzymes. It has also been suggested that PsrA, a member of the TetR family of repressors, could affect global gene expression including activation of rpoS.	1.78454e-31
NC_008750.1\|WP_011789433.1\|2457207_2458590_-\|sodium:proton-antiporter	gnl\|CDD\|224671	COG1757, NhaC, Na+/H+ antiporter [Energy production and conversion].	2.93819e-42
NC_008750.1\|WP_011789440.1\|2466244_2467717_-\|glucose-6-phosphate-dehydrogenase	gnl\|CDD\|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NC_008750.1\|WP_011789427.1\|2453017_2453239_+\|DUF2788-domain-containing-protein	gnl\|CDD\|378526	pfam10981, DUF2788, Protein of unknown function (DUF2788). This bacterial family of proteins have no known function.	2.45406e-13
NC_008750.1\|WP_011789431.1\|2455439_2456000_+\|elongation-factor-P	gnl\|CDD\|234788	PRK00529, PRK00529, elongation factor P; Validated.	1.37873e-91

>NC_008750.1|WP_011789434.1|2459375_2460590_+|pyridoxal-phosphate-dependent-aminotransferase
MRPIIKSNKLDSVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKAIVQYYQSLGIFGVDIEDIYIGNGVSELIMMAMQGLLNTDDEILIPSPDYPLWTAAANLAGGKAVHYRCDEEADWFPDLNDIKSKISSRTRGIVLINPNNPTGAVYSRELLLQVVELCRQHDLILFADEIYDKILYDEAKHIPAAGLSDDILTVTFNGLSKAYRAAGFRVGWMMLSGNLKAAKSYIEGLEMLSSMRLCANVPNQHAIQTALGGYQSINELILPNGRLTVQRDACYELLNQIPGVSVKKPKGALYAFPKLDMKKFNLRDDERLVLDLLREKKILLVHGSAFNWPEPDHLRVVFLPYKEDLNKALTEFGDFLENYRQ
>NC_008750.1|WP_011789433.1|2457207_2458590_-|sodium:proton-antiporter
MSEPTALSLIPPLVVLVLAIWLRRPILSLIIGAVSGLLLLDPSEVLNNFASASLKVMGDETIGWLILVCGCFGALIALLVRTGGALAFGHNALKFAKGPKSSLFMTFILGIVIFIDDYLNALTVGETMKRVTDKFKVSREMLAYVVDSTAAPVCVLVPLSTWAVFFGGLLVDNGVAAQGQGIAVYMQAIPYMLYAWLAVAMVLLVVLGIVPAIGPMKKAQLRAAQGEPAQEQVDFEQVQTSDEYAVKAIEEEFKHADNHGKLHNFLVPIGLLVAFTVYFDIDVWKGLLATLVFTLPYYAVQRLMPLSEMMDQMIDGFKGMLPAIGTVIAAFVFKDVCDQLLLPQYVITALSPFMTPSLLPAVVFLSMSVLAFATGSSWGIFAVTIPIVMPLAQSVGADIPLVIGALLSASSFGSQACFYSDSTVLAAQGSGCNLVSHAVTQLPYALIAAVLAFVGFILIA
>NC_008750.1|WP_011789432.1|2456171_2456993_-|hypothetical-protein
MDKKAKKILFSTYWKNGWIDSKDRVLNADDFEYAKSKGLMFEPISISHDECIASIVDLVANISKAQIAKGFLSSLTSRRLDLRSSLSSYSMAKHIPAHQYTPVISGTSYKEGIATSHSYTCSICRDVQYGVGGAEAYVNTDLNVLNFERIKWGGVRHGNILYMLFDLEQFNNTDIPEPTSDDIFCFKEILKTIENSAPEDYPSTLEKRLATVIKSSKTERQMLIEILASMGVLKPSHYDRPRRGKNDWVFAEYWRGEDKYSREAIGEYFAKYI
>NC_008750.1|WP_011789431.1|2455439_2456000_+|elongation-factor-P
MKTAHEIRPGNVIMLDGSPWVVQKTETTRSGRNAAIVKLKLKNLLLNSGTETTFKGEDKLEDIVLDRLDCTYSYFADPMYVFMDAEYNQYDVEAENLGDAAAYIVDGMEETCQVTFYDGKAISVEMPTTIVREVIYTEPSARGDTSGKVMKPATITGGGTVSVADFVKVGDKIEIDTRTGEFKKRV
>NC_008750.1|WP_011789430.1|2454216_2455395_+|elongation-factor-P-maturation-arginine-rhamnosyltransferase-EarP
MIKTPCSNHWDIFCTVVDNYGDIGVTWRLAKQLVNEYQLPVNLWVDDLASFSHILPTLDPRKAIQTFNDVNIIHWIEPLPIAFVAGSVLIEAFACELPEQVKEQLVYLHQHAPKSVPVWLNLEYLSAEDWVEGCHGLPSLQANGLKKYFYFPGFSAKTGGLICEQDLFAKRDVWQANTANKLQLFTDLGLKGIQEQDTVISVFSYETEALPALCELWQQSTVKIHALIPKGRSLNSLTHLLPCEIAALVPGQQVNHGNLTLHILPMTDQHGFDRLLWSCDVNIVRGEDSFLRAQWAAKPFIWHIYPQEDDYHLIKLGAFIQLYCDNLLPEIAQTWTNLNLAFNQGLQSAVVNHWQNLNPVSLPLLQHAKQWPIDAINAADLATRLVQFVKKS
>NC_008750.1|WP_011789429.1|2453579_2454107_+|flavodoxin-FldA
MATVGLFFGSDTGNTEAVAKMIQKKLGKKMVEVKDIAKSTKEQIAEYDLLLFGIPTWYYGEAQCDWDDFFPELEQIDFTDKLVAIFGCGDQEDYAEYFLDAMGMVGDIVQARGGIIIGHWPTAGYNFEASKGQVDDDHFIGLGIDEDRQPELTEERVDAWVKQIYEEMCLAELED
>NC_008750.1|WP_011789428.1|2453250_2453523_+|LexA-regulated-protein
MAKEATDRTTIDLFANEKRRGRPRSNPLSRSQQLKVNKRNQIQRDKAKGLKRIELKVSQDLYDALNEQALASNISRSQLIELILQRQIEC
>NC_008750.1|WP_011789427.1|2453017_2453239_+|DUF2788-domain-containing-protein
MLSQYMEQIETIGLNLFFAAIFFFIGMAIHDVLKQGNVPKFGRFIVWLVLFLGCAGFIAKGIIQITWEGSGIG
>NC_008750.1|WP_011789426.1|2452139_2452916_+|alpha/beta-fold-hydrolase
MNYVSSGQGHAVLIIHGLFGNLDNLKGLGQVLESQHQVIRVDVPNHGLSEHWDHMDYPRLAHAMIDLLDNLDIAHAHIIGHSMGGKIAMATALAFPERIISMVAADIAPVAYEPRHDIVFAALESLPLEGHTDRRFALNHLINHGIDEATAQFLLKNLQRTDTGFRWKMNLSGLKTCYPNIIGWHNQPPNPVLSYSGPSLFIRGGDSNYVNSEHRDAIMAQFPSAQAKTLEGCGHWLHAQKPAIFNRIVSEFIDKQAM
>NC_008750.1|WP_011789425.1|2451300_2451858_-|replication-initiation-negative-regulator-SeqA
MKYIEVDEELYRHIASKTERIGESASDILRRLLGLSVNTIEQVEPQAISQPSLEAVEQKPLVTSVPVIEASVPVSDFKQLVDEHKLAQQKGAVGRFLFLLESLYQQSQSQFSQILQIQGRDRLYFARSREELLKASPSANPKEIGSSGFWVTTNNNTAKKQAILVEVLVQFGCDAEVAYAISQRV
>NC_008750.1|WP_011789436.1|2461485_2462835_+|deoxyguanosinetriphosphate-triphosphohydrolase-family-protein
MTSSVWQERRHGEDKQRRFDHRSPYQRDRARILHSAAFRRLQAKTQVLGVGMNDFYRTRLTHSLEVSQIGTGIAAQLRRKYPQHKQLLCSMSLLESLCLAHDIGHPPFGHGGEVALNYMMRDHGGFEGNGQTFRILSKLEPYTLDFGMNLCRRTMLGILKYPAPYSKLFVAGEHNEITNHRQLKPSQWPPVKGIFDDDNDIFAWVLEPLSEADRSRFTSTQEGSHPALHHYPHLRTQFKSFDCSIMELADDIAYAVHDLEDAIVMGIVTASQWHQDVAPTLTNSSDAWIKQELADIGNKLFSHEHHLRKDAIGTLVNGFVTAIVISEDDVFEEPLLRFNATLEPEFAIALNVLKQLVYKYVIRKPEIQMLEYKGQQIVMGLFEAFASDPERLLPLNTQVRWRESEQQGLNTHRILADYISGMTDEFAGRLYQQLFSPKAGSNVELSKEM
>NC_008750.1|WP_041408186.1|2463024_2463666_-|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase
MLENNWSLQPQDIFKRSPIVPVMVINKIEHAVPLAKALVAGGISVLEVTLRTPCALEAITKIAKEVPEALVGAGTILNETQLEQAIAAGAQFIITPGATVELLKAGMQGPIPLIPGVASISEVMAGMALGYTHFKFFPAEASGGVDALKAFSGPLADIRFCPTGGITPSSYKDYLALKNVDCIGGSWIAPTDAMEQGDWARITQLCKDAIGAL
>NC_008750.1|WP_041408385.1|2463685_2465512_-|phosphogluconate-dehydratase
MHSVVQAVTDRIIARSKASRAGYLAALNDARHHGVHRSSLSCGNLAHGFAACKPDDKNALRQLNKANIGIVTAFNDMLSAHQPYESYPELLKKACQEVGSVAQVAGGVPAMCDGVTQGQPGMELSLLSREVIAMATAVGLSHNMFDGALLLGICDKIVPGLLIGALSFGHLPMLFVPAGPMKSGIPNKEKARIRQQFAQGKVDRAQLLEAEAQSYHSAGTCTFYGTANSNQLMLEVMGLQLPGSSFVNPDDPLREALNKMAAKQMCRLTEMGTQYTPIGEVVSEKSVVNGIVALLATGGSTNLTMHIVAAARAAGIIVNWDDFSELSDAVPLVARVYPNGHADINHFHAAGGMAYLIKELLDAGLLHEDVNTVAGFGLRRYTQEPRLLDGELCWVDGPTTSLDTEVLTSVASPFQGNGGLKLLKGNLGRAVIKVSAVQEQHRVVEAPAVVIDDQNKLDALFKAGALDRDCVVVVKGQGPKANGMPELHKLTPLLGTLQDKGFKVALLTDGRMSGASGKVPAAIHLTPEALDGGLIAKVQDGDLIRVDALTGELSLLVSETELATRAAGIVDLHRSRYGMGRELFSALRSNLSSPETGARCTNAIDELY
>NC_008750.1|WP_011789439.1|2465536_2466235_-|6-phosphogluconolactonase
MIKETVFKSFDTPSALEQQLANKIASQLQEAVDARGKASLVVSGGSTPLKLFQLLSMKSIDWSDVYITLADERWVDVEDHASNERLVREHLLQHRAANAKFRGLKNMFSTAEAGADMAGESLSNFPRPFDVVVLGMGNDGHTCSWFPCSAELEHALTTQDLCVATNPTTAPHGRMTLSKSAILNSRQIYLHLVGEQKLSVYRQALESDDVHAMPIRAVLAQRKTPVDVFWSA
>NC_008750.1|WP_011789440.1|2466244_2467717_-|glucose-6-phosphate-dehydrogenase
MGKTTSGAKACDFVLFGTKGDLARRKLLPSLYQLDKAELLDKDTKVIGVAKDEFSQEEFRELVTLALNTFVKESLCEETLQRFLSRCHYIGTNFTDSAGYSAFHDLLKPEERVMVSYFATPPAIFGDICRCLHEQDLIHPDSRVVLEKPIGSDLESSRVINDQVSAYFKERQVYRIDHYLGKETVQNLIALRFANSLFASKWDNRTIDHVQITVAEEVGIEGRWGYFDKAGQMRDMIQNHLLQVLTLVAMDPPVNLDADSIRDEKVKVLKSLRPINSDNVYENTVRGQYSAGFLKGSPVPGYLEEEGANLQSHTETFVAIRVDIDNWRWAGVPFYLRSGKRMPFKSSEIVVYFKNPPHNLYRSSYRNLPPNKLTIRLQPHEGVEIQMMNKVPGLEQKQRLQTTKLDLSFSDTFKNERIADAYERLLLEAMLGNQALFVRRDEVEQAWTWVDGIIQSWEQSNEKPKPYPAGTWGPVASVALITKDGRSWDE
>NC_008750.1|WP_011789441.1|2468027_2468882_+|MurR/RpiR-family-transcriptional-regulator
MNTLEKVQKSLTHFSKSERKVAEVILASPQTAIHSSIATLAKMADVSEPTVNRFCRRLDTKGFPDFKLHLAQSLANGTPYVSRHVEEDDSTESYTTKIFESSMASLDTARQSLDVSAINKAVDILTQAKTISFFGLGASASVAHDAQNKFFRFNVPVICFDDVLMQRMSCINSNEGDVVVLISHTGRTKSLIEIARLARENGAAVIGITARNSPLSMECTLPVTMEVPEDTDMYLPMASRLAQLVTIDVLATGFTLRRGPRFRDNLKRVKEVLKESRINKDPIL
>NC_008750.1|WP_011789442.1|2469066_2470506_+|pyruvate-kinase
MFRRTKIVTTLGPATDRDDNLRRIIAAGANVVRLNFSHGSPEDHLKRATQAREIAKELGVHVAILGDLQGPKIRVSTFKDNKKVQLKLGQAYVLDAELAKGEGDETQVGIDYKQLPDDVTVGDILMLDDGRVQLRVEGVEGRKVHTTVTVAGPLSNNKGINKQGGGLSAAALTEKDKADILTAAMIQVDYLAVSFPRSGADLDYARDLARQAGCNALIVAKVERAEAVATDEAMDDVILASDVVMVARGDLGVEIGDAALVAVQKKLIARSRQLNKIVITATQMMESMISSPMPTRAEVMDVANAVLDGTDAVMLSAETAAGDFPEETVKAMANVCVGAESHPSVKVSKHRLDARFTSVEETIALSTMYAANHLEGVKAIIALTESGATPQMMSRISSSLPILGLSRHATTLAKMALYRGVLPIYFDSTIYPADLLAQKALESLTTAGYLQSGDLVLMTKGDAMETIGGTNTCKVLIVA
>NC_008750.1|WP_011789101.1|2470673_2472047_+|IS4-like-element-ISSpu9-family-transposase
MIKGNNDWAEEQFGHAKLGDPRRTARLVKMASDLAQHPGKSVVKSSPSPASMEGAYRFIRNDNVSADDIAEAGFRATVNQAHRYPLLLAIEDTTTLSYKHRSIRADLGHVNQGNRYRGLLAHSILLFAPETLDVVGLIEQHRWTRDIKTRGIRRENLKRPYEEKEGYKWESASRNMAARLGTAMANVISVCDREADIYDYLLYKIANQQRFVVRSMMSRHIEEGSDKLYHFASELNSVKQRQIQIAQRGGRKAREVTLDVKYAAVTLKTPANKKGSPISLNYVGCSEVGDEEKTLNWHILTNEPVNSAEDALKIIGYYEKRWLIEEYHKVWKSEGTGVEDLRVQSKDNLDRLATIYAFLAVRIFQLKFANEQIKDISSEKILSPRAWKLLWLKRIKTPPPEEVPTAKWAYEHLARLGGWKDSKRNGRASVKTLWEGWLKLQAILEGYELALSLEQDL
>NC_008750.1|WP_011789443.1|2472166_2474446_-|acyl-CoA-dehydrogenase
MLTIIILALIAIVVLFAVKNIRMQFITRPVFSFFKKVLPPLSDTEREAMEAGDVWWEGELFRGNPNWNILHSYGKPTLSAEEKDFIDNQVMTALTMIDDFDIVHNRKDLPPELWEYFKKEGFFALIIPKKFGGKAFSAYANSTIVSKLASRSVSAAVTVMVPNSLGPGELLTHYGTNEQKERWLPALAKGDEIPCFALTGPEAGSDAGAIPDVGIVCRDTFNGEEMLGLKLTWDKRYITLAPVATVLGLAFQMRDPEGLLGDKKNLGITCALIPTDHPGVVIGRRHNPLGMAFMNGTTQGKDVFIPLDWIIGGPDFAGKGWRMLVECLSAGRGISLPALATASGHMATKTTTAYSYVRHQFGMAIGQFEGVQEALARIIANTYQLEAARRLTTTGIDLKVKPSVVTAIAKFHMTELGRSVMNDAMDIQSGKGIQLGPKNYLGHPYMSNPISITVEGANILTRSLMIFGQGATRCHPYVLAEMEAAAMENQHEALERFDSLLMGHMGYATRNAFSALVNALTGSVFGNAPVSGETKQYYKDMSRISSALALMTDLSMLIMGGDLKRKEMLSARMGDVLSQLYLGSATLKLFEDNGRQQDDLPAVRYVMANRLHLAAKALEDTIRNFPNRPVSWLLRALIFPLGNHFNAPSDKMATELASGMLKPGPARERITFLCPEFEGDKGGIAEVEQAFVAQYACKEIYKKLKKAQRAGELPAKVPNLVLFAKALETSVITADEEQKLQHADKLRLAAIHVNDFETL
>NC_008750.1|WP_011789444.1|2474458_2475100_-|TetR/AcrR-family-transcriptional-regulator
MASRSDTKTRILDAAEKLFAERGFSETSLRLITSKAEVNLASVNYHFGSKKELIRAVLARYLDVFMPAASTEIKRLDAIPAQATLEEILSSLVAPLLELNQLRTEGTTIFLQLLGRGYIESQGHLRWFITTHYGQHLDTFVSAVSASAPHIPPAEMFWRLHFTLGTIVFTMASADALNDIAKAEFGEHNDIEAVIRKVIPYMAAGVSVPVSPQ

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Crispr_ID: NC_008750_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008750_5

2522578-2524105

TypeI-F

I-F

Consensus_repeat	Method
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	CRISPRCasFinder
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	CRT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	PILER-CR

25 spacers

DinG,cas6f,cas7f,cas5f,cas8f,cas3-cas2,cas1

The CRISPR arrays of NC_008750_5

>merge|NC_008750|5|2522578-2524105|CRISPRCasFinder,CRT,PILER-CR
TCTACAAGCCGCCAGTGCGGCGGTGAACTTGAATTTTTAAATACTTCACCTTCTCTTGTGTTTCTAAGCCGCCTGTGTGGCGGTGAACGTGTTAGGTGGTAAAACGCTACTCATAGAGTCTTTCTAAGCCGCCTGTGTGGCGGTGAACCAAATTGAAATGGAGAACAAGTACCGCCAGTATTTCTAAGCCGCCTGTGTGGCGGTGAACACCAAAGCGATTGCTAAAATCACGGCTGTACATTTCTAAGCCGCCTGTGTGGCGGTGAACAGGTTGTACATAGCGGTGTAGTTTATCCCCTATTTCTAAGCCGCCTGTGTGGCGGTGAACTAGCGATTGCAGATACCTATCTTGTTCAGTTATTTCTAAGCCGCCTGTGTGGCGGTGAACTCGTATTCGACCAGTTCGAGTTTCCGACCAATTTTCTAAGCCGCCTGTGTGGCGGTGAACGTCATAATCTTAAGCTCGTCGTACTGCCAGATTTTCTAAGCCGCCTGTGTGGCGGTGAACGCCAGCTTGACGCCACCTTGTGGGCGGCTGTATTTCTAAGCCGCCTGTGTGGCGGTGAACCGAATCGCCGTTTCAACGTGCTTTTTCATGAATTTCTAAGCCGCCTGTGTGGCGGTGAACGAATTAAGTGATGCCGCCATTTGCAGCGGATCTTTCTAAGCCGCCTGTGTGGCGGTGAACGCCATTGTGACAAAAATAAAACAGGCTGGAATTTTCTAAGCCGCCTGTGTGGCGGTGAACTCGCTTTATTCTTCAATTAATACCATTTGTGATTTCTAAGCCGCCTGTGTGGCGGTGAACGTTGAAATGGTTCAACTAGGCATGGCACCAATTTTCTAAGCCGCCTGTGTGGCGGTGAACTAGCCGCAACAGCTAAAACCGCAGCACCAACATTTCTAAGCCGCCTGTGTGGCGGTGAACAGATATGAGAACAGCTTTAGGTCAAACAGCTATTTCTAAGCCGCCTGTGTGGCGGTGAACGAGCAGTAAAGGTGCAGTCAATTTGCTTTATTTTTCTAAGCCGCCTGTGTGGCGGTGAACAATATTTTCATATTAGTTTCCAAATAAATTTTTTTCTAAGCCGCCTGTGTGGCGGTGAATGGTATGGGTATCAATCGCCCATGGGTGTGATCTTTCTAAGCCGCCTGTGTGGCGGTGAACATTGTGATTATGCCCGTCTAGCTTATACAGACTTTCTAAGCCGCCTGTGTGGCGGTGAACCAAACGGTAACGCTAAACCCTGTTGCCAAATCTTTCTAAGCCGCCTGTGTGGCGGTGAACAACCTTCAGCAATTGCCATAATTGCTTCACCTTTTCTAAGCCGCCTGTGTGGCGGTGAACGTCTCACGCCATGTTTCGAGGTTTTGCCAATCTTTCTAAGCCGCCTGTGTGGCGGTGAACACAAAAGCGGTCGCTGCAATGGTGGCCGTGGTTTTCTAAGCCGCCTGTGTGGCGGTGAACAGTAAGAGAATTTGAGCTTCATAATGTTCAATTTTCTAAGCCGCCTGTGTGGCGGTGAAC

>NC_008750|5|5|2522578-2524105|CRISPRCasFinder
TCTACAAGCCGCCAGTGCGGCGGTGAAC	TTGAATTTTTAAATACTTCACCTTCTCTTGTG
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTGTTAGGTGGTAAAACGCTACTCATAGAGTC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	CAAATTGAAATGGAGAACAAGTACCGCCAGTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	ACCAAAGCGATTGCTAAAATCACGGCTGTACA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AGGTTGTACATAGCGGTGTAGTTTATCCCCTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TAGCGATTGCAGATACCTATCTTGTTCAGTTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TCGTATTCGACCAGTTCGAGTTTCCGACCAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTCATAATCTTAAGCTCGTCGTACTGCCAGAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GCCAGCTTGACGCCACCTTGTGGGCGGCTGTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	CGAATCGCCGTTTCAACGTGCTTTTTCATGAA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GAATTAAGTGATGCCGCCATTTGCAGCGGATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GCCATTGTGACAAAAATAAAACAGGCTGGAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TCGCTTTATTCTTCAATTAATACCATTTGTGA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTTGAAATGGTTCAACTAGGCATGGCACCAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TAGCCGCAACAGCTAAAACCGCAGCACCAACA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AGATATGAGAACAGCTTTAGGTCAAACAGCTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GAGCAGTAAAGGTGCAGTCAATTTGCTTTATT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AATATTTTCATATTAGTTTCCAAATAAATTTT
TTTCTAAGCCGCCTGTGTGGCGGTGAAT	GGTATGGGTATCAATCGCCCATGGGTGTGATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	ATTGTGATTATGCCCGTCTAGCTTATACAGAC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	CAAACGGTAACGCTAAACCCTGTTGCCAAATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AACCTTCAGCAATTGCCATAATTGCTTCACCT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTCTCACGCCATGTTTCGAGGTTTTGCCAATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	ACAAAAGCGGTCGCTGCAATGGTGGCCGTGGT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AGTAAGAGAATTTGAGCTTCATAATGTTCAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC

>NC_008750|5|1|2522578-2524105|CRT
TCTACAAGCCGCCAGTGCGGCGGTGAAC	TTGAATTTTTAAATACTTCACCTTCTCTTGTG
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTGTTAGGTGGTAAAACGCTACTCATAGAGTC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	CAAATTGAAATGGAGAACAAGTACCGCCAGTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	ACCAAAGCGATTGCTAAAATCACGGCTGTACA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AGGTTGTACATAGCGGTGTAGTTTATCCCCTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TAGCGATTGCAGATACCTATCTTGTTCAGTTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TCGTATTCGACCAGTTCGAGTTTCCGACCAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTCATAATCTTAAGCTCGTCGTACTGCCAGAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GCCAGCTTGACGCCACCTTGTGGGCGGCTGTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	CGAATCGCCGTTTCAACGTGCTTTTTCATGAA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GAATTAAGTGATGCCGCCATTTGCAGCGGATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GCCATTGTGACAAAAATAAAACAGGCTGGAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TCGCTTTATTCTTCAATTAATACCATTTGTGA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTTGAAATGGTTCAACTAGGCATGGCACCAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TAGCCGCAACAGCTAAAACCGCAGCACCAACA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AGATATGAGAACAGCTTTAGGTCAAACAGCTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GAGCAGTAAAGGTGCAGTCAATTTGCTTTATT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AATATTTTCATATTAGTTTCCAAATAAATTTT
TTTCTAAGCCGCCTGTGTGGCGGTGAAT	GGTATGGGTATCAATCGCCCATGGGTGTGATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	ATTGTGATTATGCCCGTCTAGCTTATACAGAC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	CAAACGGTAACGCTAAACCCTGTTGCCAAATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AACCTTCAGCAATTGCCATAATTGCTTCACCT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTCTCACGCCATGTTTCGAGGTTTTGCCAATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	ACAAAAGCGGTCGCTGCAATGGTGGCCGTGGT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AGTAAGAGAATTTGAGCTTCATAATGTTCAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC

>NC_008750|5|1|2522818-2524105|PILER-CR
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AGGTTGTACATAGCGGTGTAGTTTATCCCCTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TAGCGATTGCAGATACCTATCTTGTTCAGTTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TCGTATTCGACCAGTTCGAGTTTCCGACCAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTCATAATCTTAAGCTCGTCGTACTGCCAGAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GCCAGCTTGACGCCACCTTGTGGGCGGCTGTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	CGAATCGCCGTTTCAACGTGCTTTTTCATGAA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GAATTAAGTGATGCCGCCATTTGCAGCGGATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GCCATTGTGACAAAAATAAAACAGGCTGGAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TCGCTTTATTCTTCAATTAATACCATTTGTGA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTTGAAATGGTTCAACTAGGCATGGCACCAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	TAGCCGCAACAGCTAAAACCGCAGCACCAACA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AGATATGAGAACAGCTTTAGGTCAAACAGCTA
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GAGCAGTAAAGGTGCAGTCAATTTGCTTTATT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AATATTTTCATATTAGTTTCCAAATAAATTTT
TTTCTAAGCCGCCTGTGTGGCGGTGAAT	GGTATGGGTATCAATCGCCCATGGGTGTGATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	ATTGTGATTATGCCCGTCTAGCTTATACAGAC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	CAAACGGTAACGCTAAACCCTGTTGCCAAATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AACCTTCAGCAATTGCCATAATTGCTTCACCT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	GTCTCACGCCATGTTTCGAGGTTTTGCCAATC
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	ACAAAAGCGGTCGCTGCAATGGTGGCCGTGGT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC	AGTAAGAGAATTTGAGCTTCATAATGTTCAAT
TTTCTAAGCCGCCTGTGTGGCGGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008750.1\|WP_011789474.1\|2510362_2511304_-\|lauroyl-Kdo(2)-lipid-IV(A)-myristoyltransferase	unknown	unknown	gnl\|CDD\|236355
NC_008750.1\|WP_011789490.1\|2538569_2539691_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373022
NC_008750.1\|WP_082785992.1\|2520344_2522246_-\|ATP-dependent-DNA-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NC_008750.1\|WP_011789488.1\|2535676_2536894_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NC_008750.1\|WP_011789472.1\|2508862_2509879_+\|hydrogenase-expression/formation-protein-HypE	unknown	unknown	gnl\|CDD\|100033
NC_008750.1\|WP_011789476.1\|2514103_2515087_-\|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|234780
NC_008750.1\|WP_011789482.1\|2524929_2525958_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	pfam09615_cas7f_CAS-I-F	gnl\|CDD\|378222
NC_008750.1\|WP_011789477.1\|2515610_2517119_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NC_008750.1\|WP_011789473.1\|2509878_2510226_+\|hydrogenase/urease-nickel-incorporation-protein-HypA	unknown	unknown	gnl\|CDD\|376468
NC_008750.1\|WP_011789475.1\|2511700_2514088_-\|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234804
NC_008750.1\|WP_006081370.1\|2511400_2511697_-\|integration-host-factor-subunit-alpha	unknown	unknown	gnl\|CDD\|178961
NC_008750.1\|WP_011789481.1\|2524252_2524927_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	pfam09618_cas6f_CAS-I-F	gnl\|CDD\|187870
NC_008750.1\|WP_011789483.1\|2525983_2526934_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	pfam09614_cas5f_CAS-I-F	gnl\|CDD\|378221
NC_008750.1\|WP_011789486.1\|2532035_2533013_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|132676
NC_008750.1\|WP_011789485.1\|2528609_2532023_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3-cas2	cas3-cas2-CAS-I-F	gnl\|CDD\|274201
NC_008750.1\|WP_011789484.1\|2526930_2528229_-\|type-I-F-CRISPR-associated-protein-Csy1	cas8f	cd09735_cas8f_CAS-I-F	gnl\|CDD\|187866
NC_008750.1\|WP_011789478.1\|2517308_2519294_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|227112
NC_008750.1\|WP_011919229.1\|2519880_2520171_+\|cytochrome-c3-family-protein	unknown	unknown	gnl\|CDD\|373118
NC_008750.1\|WP_011789487.1\|2534486_2535680_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|365903
NC_008750.1\|WP_041408187.1\|2533154_2533349_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008750.1\|WP_011789474.1\|2510362_2511304_-\|lauroyl-Kdo(2)-lipid-IV(A)-myristoyltransferase	gnl\|CDD\|236355	PRK08943, PRK08943, lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated.	0
NC_008750.1\|WP_011789490.1\|2538569_2539691_-\|hypothetical-protein	gnl\|CDD\|373022	pfam14350, Beta_protein, Beta protein. This family includes the beta protein from Bacteriophage T4. Beta protein prevents the gop protein from killing the bacterial host cell.	1.07514e-76
NC_008750.1\|WP_082785992.1\|2520344_2522246_-\|ATP-dependent-DNA-helicase	gnl\|CDD\|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	5.36293e-148
NC_008750.1\|WP_011789488.1\|2535676_2536894_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.89438e-69
NC_008750.1\|WP_011789472.1\|2508862_2509879_+\|hydrogenase-expression/formation-protein-HypE	gnl\|CDD\|100033	cd02197, HypE, HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis. HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the ATP-binding domains of the AIR synthases, selenophosphate synthetase (SelD), and FGAM synthase and is thought to bind ATP.	2.93034e-167
NC_008750.1\|WP_011789476.1\|2514103_2515087_-\|phenylalanine--tRNA-ligase-subunit-alpha	gnl\|CDD\|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NC_008750.1\|WP_011789482.1\|2524929_2525958_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0
NC_008750.1\|WP_011789477.1\|2515610_2517119_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	1.34366e-55
NC_008750.1\|WP_011789473.1\|2509878_2510226_+\|hydrogenase/urease-nickel-incorporation-protein-HypA	gnl\|CDD\|376468	pfam01155, HypA, Hydrogenase/urease nickel incorporation, metallochaperone, hypA. HypA is a metallochaperone that binds nickel to bring it safely to its target. The targets for Hypa are the nickel-containing enzymes [Ni,Fe]-hydrogenase and urease. The nickel coordinates with four nitrogens within the protein. The four conserved cysteines towards the C-terminus bind one zinc moiety probably to stabilize the protein fold.	2.23434e-39
NC_008750.1\|WP_011789475.1\|2511700_2514088_-\|phenylalanine--tRNA-ligase-subunit-beta	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NC_008750.1\|WP_006081370.1\|2511400_2511697_-\|integration-host-factor-subunit-alpha	gnl\|CDD\|178961	PRK00285, ihfA, integration host factor subunit alpha; Reviewed.	4.31032e-63
NC_008750.1\|WP_011789481.1\|2524252_2524927_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|187870	cd09739, Cas6_I-F, CRISPR/Cas system-associated RAMP superfamily protein Cas6f. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6f is an endoribonuclease that generates crRNA; This family is specific for CRISPR/Cas system I-F subtype; Possesses RRM fold; also known as Csy4 family.	1.33493e-67
NC_008750.1\|WP_011789483.1\|2525983_2526934_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|378221	pfam09614, Cas_Csy2, CRISPR-associated protein (Cas_Csy2). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.	2.74499e-138
NC_008750.1\|WP_011789486.1\|2532035_2533013_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|132676	TIGR03637, cas1_YPEST, CRISPR-associated endonuclease Cas1, subtype I-F/YPEST. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the YPEST subtype of CRISPR/Cas system.	1.85892e-171
NC_008750.1\|WP_011789485.1\|2528609_2532023_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|274201	TIGR02562, conserved_hypothetical_protein, CRISPR-associated helicase Cas3, subtype I-F/YPEST. The helicase in many CRISPR-associated (cas) gene clusters is designated Cas3, and most Cas3 proteins are described by model TIGR01587. Members of this family are considerably larger, show a number of motifs in common with TIGR01587 sequences, and replace Cas3 in some CRISPR/cas loci in a number of Proteobacteria, including Yersinia pestis, Chromobacterium violaceum, Erwinia carotovora subsp. atroseptica SCRI1043, Photorhabdus luminescens subsp. laumondii TTO1, Legionella pneumophila, etc.	0
NC_008750.1\|WP_011789484.1\|2526930_2528229_-\|type-I-F-CRISPR-associated-protein-Csy1	gnl\|CDD\|187866	cd09735, Csy1_I-F, CRISPR/Cas system-associated protein Csy1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins; Predicted subunit of the Cascade complex; signature gene for I-F subtype; also known as Csy1 family.	1.19313e-164
NC_008750.1\|WP_011789478.1\|2517308_2519294_+\|TonB-dependent-receptor	gnl\|CDD\|227112	COG4771, FepA, Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism].	6.74509e-142
NC_008750.1\|WP_011919229.1\|2519880_2520171_+\|cytochrome-c3-family-protein	gnl\|CDD\|373118	pfam14537, Cytochrom_c3_2, Cytochrome c3.	9.52049e-10
NC_008750.1\|WP_011789487.1\|2534486_2535680_+\|serine-hydrolase	gnl\|CDD\|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	4.09394e-61

>NC_008750.1|WP_082785992.1|2520344_2522246_-|ATP-dependent-DNA-helicase
MQRAFLQGGVLSTHIQGFSARESQMQMAQGVSEAIASKGNLVIEAGTGVGKTFAYLIPALLSGKQVIISTGSKNLQEQLFFKDLPALTSMFGIEPKLALLKGRNNYLCQWRLDKQMREASHIEARLLDDLLKINQWAGISQDGDIGALTSVPEHSSALPLVVSTKETCLGKRCDFYEVCFTRKARSRAMDAKIIVVNHHLFFADSVLKDTGFAELLPDPDVVIFDEAHLLPDICVNYFGQQCSSRTIDDLIQKLLAIYQTELSDTGQIAQFCQRCLTKLSDWHNQLYSAGESDWRLVLGNKLLATASWDLLAELTALQNLLMAHIGRSELLDDIAIQLAELNNKLNVFFHCDNNQAAYSVEFGSRFVVLRISPINIARECQQLFVPETSWIFTSATLQVNRSLAHFAREMGIVDAAQSILDSPFDYPRQAVFCVPRQLGNVANQQQALKQLVDVCVQAIDAAQGRTFILFTSHNMLEQTALALRARTQYPLLVQGQAGKQSLLTKFRQLGNAVLLGTSSFWEGVDVRGKLLSCVIIDKLPFVSPDEPLYRARADNVSRQGGDPFTEVSLPQAIIALKQGVGRLIRDEKDRGVLILCDNRIVNRYYGQAFLNSLPPMARTRDLDKALAFLRTIP
>NC_008750.1|WP_011919229.1|2519880_2520171_+|cytochrome-c3-family-protein
MLKKMMLMSVLCFSTSLMAASLADSHSERSDCESCHKDKTPSADYVFENEQCVACHGEMKTLKGDAHTKHDGVLTCTNCHIAHEEKAPADSCKECH
>NC_008750.1|WP_011789478.1|2517308_2519294_+|TonB-dependent-receptor
MFTLQRLCKSRINCPSLPRFTPSVLSCAVAIGLSLSTTLVNAAETTSVNPDMERIVVTATQTKHSELSAPASVSVINRAELDALVIDDLASAVRYLQGVNISEGTSYGRNEISLRGLDSDYTLILINGRRINSREALTSSYGNDFDLSSIPMSAIERIEVVRGPMSSLYGSEALGGVINVILRQPTDDWQTSVGVQYDTPTKGDGGDTTKYNFYTSGALIKDKLLANLIVDSSKRDAWRSDLKPKLDALEDRDEISAIANLQWLIDSNQDLQFDLSYADDERESDWNNYGAILTNYQQAERISSGLTHNGHWNWGDTRLRYYYENVEVTDNSALIAEIGNITQTNHNLDGQSTVLLGDHMLTGGAEYRWTKLENSRNVLGDGVLDDNQSALYLQDEFNLGELNITLGGRVDHHDVYGTEFSPRLYLVYNLSSEWVIKGGGGKAFKAPNMSQSQADYIISSCRGSCTLAGNPELEPETSVNYELSTQYQTTDIGGSITYFHNDVENKIITETWNRVPGAVLTYQNVNEAKITGWELQAWYDLTDDLSLSGNYSKTDAKDKQNGTPFTLTPEDSYNIKLQWQALDGLSTFVAYHYTGEQYLRANVKSDGYGSLDIGANYQINPMFRLKLGVTNLTDSERDNAATDLDYIQKSRSVYAGITASF
>NC_008750.1|WP_011789477.1|2515610_2517119_+|methyl-accepting-chemotaxis-protein
MKEVKFRWIDQYLIHMTLKTKFAILALVPMIMIVGLAVFLNIQFQQTLIDTHFKTLQNSAQQINQITAQLHSKLPDQERQRLQNQLSHGNVNVIALNNADNKAQSIARSGGGIDDSQSQRAISGVNDQNQITIISIDNREIDALLAKDNLLVYGLMAALLFVLFLFSYYISTFVGGALYTTVMALKRAASGDLTGRLNFFEVKDEFSILAISIDTLVERQHTLVKQIAESTNKIREVVSSFRSTAQQGQSLAVNQRQHLDSLATAMEEMTAAVKEVARNAEQSSAETQEANQQVSAGGKDIETTVKAIDLLSDEISDASNAVNILNDNASKIDEVVSSINAISQQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQSATVEIKTMIESLQSGIRNLTQVMSRTVNQANEGKQHVLQTGKDLEFIAHHSNKVFEMSVLIATSAEEQSAVANEIATNLMEIRNQSHDVEQSANQSVSGCDELQATAGQLDQLMVGLKV
>NC_008750.1|WP_011789476.1|2514103_2515087_-|phenylalanine--tRNA-ligase-subunit-alpha
MQQLTEIVEQALVIIDQASDLKALDDIRVDYLGKKGKITDMMKMMGSLSPEEKPAFGQAVNDAKQAIQQKLTERIDGLKSSELEAKLIAEKIDVTLPGRTQENGGLHPVTRTIERIETFFGELGFSVKQGPEIEDDFHNFDALNISEHHPARADHDTFYFNPKLMLRTQTSGVQIRTMETEKPPLRIISPGRVYRNDYDQTHTPMFHQVEGLLVDEHVNFAELKGILHDFLRNFFEEDLQVRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRSVGIDPEKYSGFAFGMGVERLTMLRYGVNDLRAFFENDLRFLKQFK
>NC_008750.1|WP_011789475.1|2511700_2514088_-|phenylalanine--tRNA-ligase-subunit-beta
MKFSESWLREWVNPSVSREALSHQITMAGLEVDGVDPVAADFNGVVVGEVVECGQHPDADKLRVTKVSVGTGELIDIVCGAPNCRQGLKVAVAMVGAVLPGDFKIKKAKLRGMPSEGMLCSYSELGINVESDGIIELPLDAPLGTDLREYLKLDDAVIEVDLTANRADCLGMVGLAREVGVLNRQTVVEPQWQAVTPSIDAKVTINVKAPAACPRYLGRVVKNVNVKAPTPLWMQEKLRRSGIRSIDPIVDITNFVLVEFGQPMHAFDLVKLTGDIQVRLGNGDEKITLLDGSEVTIPSDTLVIADDARPLALAGVFGGEYSGVSDTTQDILLECAFFAPLAIMGKSRRLGLHTDSSHRFERGVDPEMQHKVIDRATRLVLDICGGEAGPVVEAKSDADLPKPAQILLRRSKLDRILGHHVPDTDVVEILQRLGFSVVASQDSWQVTTATYRFDMAIEEDLIEEVARIYGYDNIPNTAPVAALRMSDHKESDLSLKRVRALLVARGFQEAVTYSFVDPKLQNLVHPGEQAMVLPNPISSEMSAMRLSMFTGLLAAVGYNQSRQQSRVRLFETGLRFVPDINAESGVRQQAMLACVITGLQNDEHWAMESKTVDFFDLKGDLEAIIGLTVSASEFSFRVATHSALHPGQCAEILRNDRVIGHIGAIHPSLEKPFGLNGKTIVFELELDALLHTSLPLAQAVSKFPANRRDIAVVVDESVSAGDVMKVIRKVGENQLVGINLFDVYLGKGVEPGKKSLAIALTLQDTTRTLEEKEIAETVESVVSALKTEFNASLRD
>NC_008750.1|WP_006081370.1|2511400_2511697_-|integration-host-factor-subunit-alpha
MALTKAEMAEHLFETLGMNKRVAKEMVESFFEEIRGALESGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPISARRVVTFRPGQKLKTRVEAANTGK
>NC_008750.1|WP_011789474.1|2510362_2511304_-|lauroyl-Kdo(2)-lipid-IV(A)-myristoyltransferase
MSRQPKYFDRRFTLALLHPKYWGSWLAIGLLVIFGLMPAWLRDPIARLLAKWVIPIAKKPIRVARANLKACFPEKSAAEIEALIKDNVEHFVLVLLSQGELLVRSKAHLRRRVSLFGFEHVKKAQAAGQPIIFIMPHVWPIDYAGLRINCEMPLVTMAKAHKNGLFNWFSNRVRSSCGGHVYMREAGIRALLAELKQNNSFFYLPDEDLGPEQSVFTPFLGTVKATLPVVGRLAQAGNAQVLPVKIGYNQAQYRFELTVMPAIAPEDMQGKENEALALNKVVEQVILAYPEQYMWFLRLLKTRPEGEASIYGN
>NC_008750.1|WP_011789473.1|2509878_2510226_+|hydrogenase/urease-nickel-incorporation-protein-HypA
MHEYSIVSALIEQCEQHALANQANKITRVEIKLGVMSGVEPALLQTAFDTFKLDGICKEAQLNMQLQPLVIECLDCQTSSELNERSIVCPACQSYRTRVLDGEDMLLMQLEMEQE
>NC_008750.1|WP_011789472.1|2508862_2509879_+|hydrogenase-expression/formation-protein-HypE
MGDTPKDKSIQLSHGGGGKEMNKLIRDLFFAEFDNPILRSEEDAAKLDLHGANAFTTDSFTVSPLFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSCSVIIEEGFSINDLTTIVRSMAKELKQSGARIVCGDTKVVPKGCADGLFINTSGIGRILRPNISAANLTAGDTIIVSRDIGCHGAAILMAREGLVLESALQSDCATLWPVVEQLIAANIPIHAMRDATRGGLSAVLNEWAVASNVGITVNEASIPVCDEVKGLCELYGFEAMDLANEGTFVLAVPQEIALGALEIMQRFGHCEQAAIIGTVTDETAGKVILKTPWNTKRYLDLPQGELLPRIC
>NC_008750.1|WP_011789481.1|2524252_2524927_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MKYYLDITLLPDAEANLGFLWHKVYQQIHLMLVEHKVSVENSAIGLSFPKYDAKSFSDNTKFPLGDKLRLFAGTEQQLADLKVAQWLARLADYVHIKAIKAVPDNVSEYAYFKRRHFKSPDKLRRNIDARAIVIAQKNGFAINEVKTRLLASIDNLDTKSKLPFINLRSLSTEKDVSPADRRKFLLFIECEKVTKPSQNNGLFNCYGLSRRAQTEQAAVPWFEG
>NC_008750.1|WP_011789482.1|2524929_2525958_-|type-I-F-CRISPR-associated-protein-Csy3
MAKKENVASVLAFEKKLVVSDGYMYGTSWTERSQIVPLALREKSVRGTISNRLKAAIKNDPAKLNAEVEKANLQRVDACALAPEHDTLNLQFTIKVLGGITEPSACNNALFKQSYRAAAATYIENQGFTELARRYATNLANARFLWRNRVGAENIEVQVRAKNSTLDQSWTFDAAQFSTKSFDNNDAQINALANHIATVLSSEDDFLLLDINCFAQVGRAQEVYPSEELVLDKGKGEKSKILYNVNGLAAMHSQKLGNALRTIDTWYPEFTDPETSAGAIAIEPYGAVTNLGKAYRTPAAKQDFYSFFDLWARGEKLSRIEDEHYVMAVLVRGGVFGESDKE
>NC_008750.1|WP_011789483.1|2525983_2526934_-|type-I-F-CRISPR-associated-protein-Csy2
MIGEVKKLLIIPHIKVHNANALSSPFTIGFPAMTAWLGGVHALQRHVNAQDIPVNFLATGVVSHDVNLQTYKGDNDYVHSIVGTGNPLDKTGARSAFIEEARCHLEISLVIEFNGITIDEHEHLLSAVTQLLHAKMKLAGGDIKSFQPPFCINNSEGDDKDLRKLQRHLMPGYVLIERRDLMQAAMAEGVDALNALIDYLAVHHSCDQDEEGNIEWRSYRKTLENKPAGWVVPIATGYHALSELSDAKNQRDPNTSHRFAESLVTLGEFKMPHRLHSVEQMLWRYHIDGDLYLCQQKHSESPKSASSGLTSIESEF
>NC_008750.1|WP_011789484.1|2526930_2528229_-|type-I-F-CRISPR-associated-protein-Csy1
MIDGTISEFFADRKSAWLKKNIKASMSDVEIKALEIECETQFSLANWLPNAASRAGQIAISTHPCTFSHPSARKNKNGYVTSIIAHSEKANDGFLRSGNVEVAADALGNAAALDVYKFLTLVMADGETLIQHLERDSEQAVNLLAAASKETYPDYQTLKQAFLAMTATSSESITSSKIKQVYFPLNRGNSVNGHLASIEYHQLSLLTASGIVFELRQRLDAMRFGETIKEARDKKKTNQFHQGYKEIYNLTTIGYGGTKPQNISVLNNQNGGKAHLLLSLPPNLKNRDVHFPHSDFFSQTLRYTQCKNQFQALHQLYRGDDNNMHIRAQRDDYYQSVIDHVIEKMWQVRSVAQAQFRREDSLLPTVQQTWLCEHTKILRETTDDWLDVICNAITVFLFHGYEKTLGSKAIKFGDAEYRQMQKIVLSNKEALR
>NC_008750.1|WP_011789485.1|2528609_2532023_-|type-I-F-CRISPR-associated-helicase-Cas3
MMVTFISQCEKNALKKTRRVLDAFANRIGDNTWQTLITEDGLLTVKKMLKQTASKSTAVSCHWIRSRARSQLLWVVGNRLKFNEQGIVPVNSTRRNLLASDIENDWHYLPLIKALAGLSALLHDWGKATTLFQDKLNPSSQHRFKGDPIRHEWISLLLLHAFIHTTDADTDEQWLSRLSEADIDESRLKQFIQADTAKPLNALPPIAKLVAWLIVSHHRLPLPDKDLCTDYKTESAASLDIMLARISKEWGYQNRYDEQDYEKRLKSCFRFPNGLLSNSKPWLQQVKKWSARLLQQQTQVQQCLTDGSYRLVLNHARLCLMLGDHFYSSQQADQKWQDTTGLYANTDRATNTLKQKLDEHLVGVARCALNTAHLLPAFEQEPPVAEDIHSLRKPSPKPYQWQDKAVDKITTWRYAIDKQAKQKYGFFTVNMASTGCGKTFANAKVMRALSGDSKSLRFILALGLRTLTLQTGDEYRERVGLDNSELAVLIGSRAVMELHQQRKAELDEKNVEHTGSSSQETLLDEEIDFDCAIPEQGLSTVLTCNRDKQFLYAPVLACTIDHLMAATETKRGGCYILPTLRLMSSDLVIDEIDDFTGDDLIAIGRLIHLAGMLGRKVMISSATIPPFMAEGYFKAYRDGWQLYCKTRSASSVIGCAWIDEFSTQVTSNCVAELPAAINQYRQEHDAFITKRIAKLKQQPAKRKADISACQAIIEQHQGQSNQQQTVIESKQLAYFNVIAQSALQKHLQHHVHDINTQLNVSFGVVRVANISPCVALTQYLLAKEWPLDTEVRVMAYHSQQVLLLRSIQEQHLDKVLKRKEAENEPPQALSDPVIRQHLAAIAAQSNAIRNVLFILVATPVEEVGRDHDFDWAVIEPSSYRSIIQLAGRVKRHREGEVTTANIALLQYNWKGIRDNHLERARVFNRPGYEDICSLETHDLNCLINTLDIAERLDAIPRIHKPVQLTADYMRHVSRCGSLIELEHIATWSWLSNYKMQGEGAQTSPATLQGWLNQHWFLTALAQQLTPFRHSEPSIKVFLVFDNDQNTSRFCEKNEEGYADDRENILNIQRIALAPQARSRLWLVRDYDRACAEFADKSLDSQQPLSQRRVSLRYGELNFPHNEKQQYAYNDQLGLVKL
>NC_008750.1|WP_011789486.1|2532035_2533013_-|type-I-F-CRISPR-associated-endonuclease-Cas1
MDDFSPSDLKTILHSKRANMYYLEYCRVMQKDGRVLYLTEAKNENQYFNIPIANTTVLLLGNGTSITQAAMRMLAQAGVLVGFCGGGGTPLYMTCEVEWLTPQSEYRPTEYLHGWMQFWFDDEKRLLAAKTFQQARIQFIEQVWQRDRELKTEGFIFKDPAIQAALETFHARTEAATKQSDLLLTEAQLTKVLYKHAANNTQLKDFTRQHQSADIANDFLNHGNYLAYGLAASCLWVLGIPHGFAVMHGKTRRGALVFDVADLIKDAIVLPWAFVCAKEKASEQEFRQQVLQAFTDHNALDFMFNTVKGIALQDYSAEQIAAQGL
>NC_008750.1|WP_041408187.1|2533154_2533349_+|hypothetical-protein
MNIPNTVVTNLPNLNAGQVLDLSSADYAKHVVLLNGTMQPQGRAHQEANMSTIARTTSRTRALR
>NC_008750.1|WP_011789487.1|2534486_2535680_+|serine-hydrolase
MTTNTFPLPRSVVPIPLSARIQNVIEQALHEQRLVGAVVLVARNCELIYQQAAGYADRESARPMAVDTVFRLASVSKPIVSAAALVLVAQGRLELDENIGNWLPDFQPRLADGRLARITVRQLLSHTAGLGYRFFEADEKSPYALVGVSDGMDASGISLQENLKRIASVSLLYEPGTAWGYSLATDVLGALIERVYGTSLNEAIHHLVTGPLGMNDTGFVAGDPQRMATAYVNDAPQPHQLAEGETVSPFEGTIGIKYSPARIFDAQSFPSAGAGMAGTAGDFLRLLEALRQEGGGLLPKELVAEMARDQTGGLELPNSPGFGFGLGFSVLRDPKLAASPESAGTWRWGGAYGHSWFVDRAQGLSMVAFTNTLYEGMCGRFVTGLRDAVYDGSEVQR
>NC_008750.1|WP_011789488.1|2535676_2536894_+|MFS-transporter
MKSTAPDRLPLAALLALALAGFVTILTEALPAGLLPQIGAGLGVSEALAGQLVTVYAIGSLLMAIPLMTITQGVRRRPLLLAAIVGFAVANTVTTFSTSYTLTLVARFLAGVAAGLLWALLAGYASRMVPEHLKGRAIAIAMVGTPLALSLGVPAGTLLGNLVGWRVCFAMMSLLALMLIVWIRLKVPDFAGQATGKRLSLGQVFTLPGIRPVLFVVLTFVLAHNILYTYIAPFLSAAGMAERTDLVLLVFGMTALLGIWVIGVLIDRHLRILTLASIALFALTAIVLGLAGDVPVAVYCAVAAWGLAFGGAATLFQTGLAKAAGSAADVAQSMLVTAWNLAIAGGGIVGGVLLEQLGVSSFSPALLILLVAALVVVWAARKHGFAAPEDAAIPCPSTPKQQTEV
>NC_008750.1|WP_011789490.1|2538569_2539691_-|hypothetical-protein
MQAMYFPILKAKDAEFDALHEAKEHIASSMIPLFDVPKFNPELKKYQNDSHAKATFLSEISTKIGKLRFGMPVMFDTYHWQHPNERVESGEHHLSYLYNTLKSDGVIAIPVVGYDRWDDEEYRLALRSIARNHSGKFCIRLDRFAFEDINDPEHFHDRLSEIIDSLEIIPANCHVILDLQDLSEMAIPDMISQFDSLFLAITDYGFATYSVAGCSLPNSIDKAVKRKDTTGSLLRREMVLWKYAREHYPAHQIHFGDYGVRGPSTTEIGYGNTNAKIRYTIDNEYFIVRGHKIEKPIGGFQHCALARILMDSKYYLSPDFSWGDNEIKRCSENKLGGGATTWIKIDTSHHVAYVVLEIAEFERNRVSKALNLA

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Crispr_ID: NC_008750_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008750_6

3946758-3947805

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRT

17 spacers

The CRISPR arrays of NC_008750_6

>merge|NC_008750|6|3946758-3947805|PILER-CR,CRISPRCasFinder,CRT
GTTCACTGCCGCACAGGCAGCTTAGAAACGCGCCAAAGTTGTAAATTAGGCTTAGGTACGGTTCACTGCCGCACAGGCAGCTTAGAAATCCTCCATTTGTTGTTGATGTAGTTATTACTTGTTCACTGCCGCACAGGCAGCTTAGAAATGTGTCAGTAAAAGTATCAGGCATTAATTCAGGTTCACTGCCGCACAGGCAGCTTAGAAAGACATGAGAGTATAGTTCCCGTTTAGCTTGTGGTTCACTGCCGCACAGGCAGCTTAGAAAATAAATTCACCTTAACCAAGTTCGCGCCATTTGTTCACTGCCGCACAGGCAGCTTAGAAATGAGACTTAAACCATTGCTCGCCCCAGAACGAGTTCACTGCCGCACAGGCAGCTTAGAAATGCTAGGTCGTTGGCATAGTGTTTTGGCTAAGGTTCACTGCCGCACAGGCAGCTTAGAAAATTAAATTCATTAGCAGTAACATAAACCTCGAGTTCACTGCCGCACAGGCAGCTTAGAAATTACTTAGCACGACTCGCCGTAGTTCTCAGCGGTTCACTGCCGCACAGGCAGCTTAGAAATTAACACGAGCGTGAGCGGCGTCACCATAGCGGTTCACTGCCGCACAGGCAGCTTAGAAATTTACCGTTTCTTTGGCTGCTGCAATCTTCTTGTTCACTGCCGCACAGGCAGCTTAGAAACAAGTGACACACAGCAGACGAAACAAATTCAAGTTCACTGCCGCACAGGCAGCTTAGAAAACGGAGTTTAAATCTGCATACTTAGATTTAAAGTTCACTGCCGCACAGGCAGCTTAGAAAACCAAAGGCGGCATCATGTGGCGAGTAAATACGTTCACTGCCGCACAGGCAGCTTAGAAATCCATGCGAAGGGTGACATCCAGCGACAACAAGTTCACTGCCGCACAGGCAGCTTAGAAAAATGTACCGCGACCATCGATACCATACGGATAGTTCTCTGCCGCACAGGCAGCTTAGAAAAGTGCCATCGATGGCGCAAGATAATAGCGACCGTTCACTGCCGCACAAGCAGTTTAGATG

>NC_008750|6|2|3946758-3947745|PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CGCGCCAAAGTTGTAAATTAGGCTTAGGTACG
GTTCACTGCCGCACAGGCAGCTTAGAAA	TCCTCCATTTGTTGTTGATGTAGTTATTACTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGTGTCAGTAAAAGTATCAGGCATTAATTCAG
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACATGAGAGTATAGTTCCCGTTTAGCTTGTG
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATAAATTCACCTTAACCAAGTTCGCGCCATTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGAGACTTAAACCATTGCTCGCCCCAGAACGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGCTAGGTCGTTGGCATAGTGTTTTGGCTAAG
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATTAAATTCATTAGCAGTAACATAAACCTCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	TTACTTAGCACGACTCGCCGTAGTTCTCAGCG
GTTCACTGCCGCACAGGCAGCTTAGAAA	TTAACACGAGCGTGAGCGGCGTCACCATAGCG
GTTCACTGCCGCACAGGCAGCTTAGAAA	TTTACCGTTTCTTTGGCTGCTGCAATCTTCTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CAAGTGACACACAGCAGACGAAACAAATTCAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	ACGGAGTTTAAATCTGCATACTTAGATTTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	ACCAAAGGCGGCATCATGTGGCGAGTAAATAC
GTTCACTGCCGCACAGGCAGCTTAGAAA	TCCATGCGAAGGGTGACATCCAGCGACAACAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	AATGTACCGCGACCATCGATACCATACGGATA
GTTCTCTGCCGCACAGGCAGCTTAGAAA

>NC_008750|6|6|3946758-3947805|CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CGCGCCAAAGTTGTAAATTAGGCTTAGGTACG
GTTCACTGCCGCACAGGCAGCTTAGAAA	TCCTCCATTTGTTGTTGATGTAGTTATTACTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGTGTCAGTAAAAGTATCAGGCATTAATTCAG
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACATGAGAGTATAGTTCCCGTTTAGCTTGTG
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATAAATTCACCTTAACCAAGTTCGCGCCATTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGAGACTTAAACCATTGCTCGCCCCAGAACGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGCTAGGTCGTTGGCATAGTGTTTTGGCTAAG
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATTAAATTCATTAGCAGTAACATAAACCTCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	TTACTTAGCACGACTCGCCGTAGTTCTCAGCG
GTTCACTGCCGCACAGGCAGCTTAGAAA	TTAACACGAGCGTGAGCGGCGTCACCATAGCG
GTTCACTGCCGCACAGGCAGCTTAGAAA	TTTACCGTTTCTTTGGCTGCTGCAATCTTCTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CAAGTGACACACAGCAGACGAAACAAATTCAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	ACGGAGTTTAAATCTGCATACTTAGATTTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	ACCAAAGGCGGCATCATGTGGCGAGTAAATAC
GTTCACTGCCGCACAGGCAGCTTAGAAA	TCCATGCGAAGGGTGACATCCAGCGACAACAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	AATGTACCGCGACCATCGATACCATACGGATA
GTTCTCTGCCGCACAGGCAGCTTAGAAA	AGTGCCATCGATGGCGCAAGATAATAGCGACC
GTTCACTGCCGCACAAGCAGTTTAGATG

>NC_008750|6|2|3946758-3947805|CRT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CGCGCCAAAGTTGTAAATTAGGCTTAGGTACG
GTTCACTGCCGCACAGGCAGCTTAGAAA	TCCTCCATTTGTTGTTGATGTAGTTATTACTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGTGTCAGTAAAAGTATCAGGCATTAATTCAG
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACATGAGAGTATAGTTCCCGTTTAGCTTGTG
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATAAATTCACCTTAACCAAGTTCGCGCCATTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGAGACTTAAACCATTGCTCGCCCCAGAACGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	TGCTAGGTCGTTGGCATAGTGTTTTGGCTAAG
GTTCACTGCCGCACAGGCAGCTTAGAAA	ATTAAATTCATTAGCAGTAACATAAACCTCGA
GTTCACTGCCGCACAGGCAGCTTAGAAA	TTACTTAGCACGACTCGCCGTAGTTCTCAGCG
GTTCACTGCCGCACAGGCAGCTTAGAAA	TTAACACGAGCGTGAGCGGCGTCACCATAGCG
GTTCACTGCCGCACAGGCAGCTTAGAAA	TTTACCGTTTCTTTGGCTGCTGCAATCTTCTT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CAAGTGACACACAGCAGACGAAACAAATTCAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	ACGGAGTTTAAATCTGCATACTTAGATTTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	ACCAAAGGCGGCATCATGTGGCGAGTAAATAC
GTTCACTGCCGCACAGGCAGCTTAGAAA	TCCATGCGAAGGGTGACATCCAGCGACAACAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	AATGTACCGCGACCATCGATACCATACGGATA
GTTCTCTGCCGCACAGGCAGCTTAGAAA	AGTGCCATCGATGGCGCAAGATAATAGCGACC
GTTCACTGCCGCACAAGCAGTTTAGATG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008750.1\|WP_011790720.1\|3950811_3952182_+\|MATE-family-efflux-transporter	unknown	unknown	gnl\|CDD\|240554
NC_008750.1\|WP_011790721.1\|3952184_3953174_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NC_008750.1\|WP_006086113.1\|3950295_3950586_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NC_008750.1\|WP_011790726.1\|3959282_3960113_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_008750.1\|WP_011790712.1\|3938491_3939346_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|235450
NC_008750.1\|WP_011790718.1\|3945975_3946524_+\|DUF2799-domain-containing-protein	unknown	unknown	gnl\|CDD\|378521
NC_008750.1\|WP_011790713.1\|3939820_3941185_+\|magnesium-transporter	unknown	unknown	gnl\|CDD\|225148
NC_008750.1\|WP_011790717.1\|3944760_3945618_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224632
NC_008750.1\|WP_011790714.1\|3941297_3942122_-\|molybdate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270259
NC_008750.1\|WP_011790711.1\|3938051_3938495_+\|PTS-IIA-like-nitrogen-regulatory-protein-PtsN	unknown	unknown	gnl\|CDD\|182818
NC_008750.1\|WP_011790723.1\|3954383_3957467_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NC_008750.1\|WP_011790724.1\|3957575_3958421_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NC_008750.1\|WP_011790715.1\|3942356_3943043_-\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|182507
NC_008750.1\|WP_011790722.1\|3953300_3954380_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_008750.1\|WP_011790725.1\|3958489_3959173_-\|LysE-family-transporter	unknown	unknown	gnl\|CDD\|236665
NC_008750.1\|WP_006083073.1\|3939332_3939608_+\|HPr-family-phosphocarrier-protein	unknown	unknown	gnl\|CDD\|376329
NC_008750.1\|WP_011790716.1\|3943681_3943915_+\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_008750.1\|WP_011790727.1\|3960284_3962321_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NC_008750.1\|WP_011790719.1\|3948600_3950238_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NC_008750.1\|WP_011790710.1\|3937761_3938049_+\|ribosome-hibernation-promoting-factor	unknown	unknown	gnl\|CDD\|182484

Protein	Function_ID	Function_description	E-value
NC_008750.1\|WP_011790720.1\|3950811_3952182_+\|MATE-family-efflux-transporter	gnl\|CDD\|240554	cd13149, MATE_like_2, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	1.51551e-129
NC_008750.1\|WP_011790721.1\|3952184_3953174_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.02735e-54
NC_008750.1\|WP_006086113.1\|3950295_3950586_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	1.80279e-44
NC_008750.1\|WP_011790726.1\|3959282_3960113_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	5.48116e-23
NC_008750.1\|WP_011790712.1\|3938491_3939346_+\|RNase-adapter-RapZ	gnl\|CDD\|235450	PRK05416, PRK05416, RNase adapter RapZ.	5.12213e-162
NC_008750.1\|WP_011790718.1\|3945975_3946524_+\|DUF2799-domain-containing-protein	gnl\|CDD\|378521	pfam10973, DUF2799, Protein of unknown function (DUF2799). Some members in this family of proteins are annotated as yfiL which has no known function.	4.35157e-31
NC_008750.1\|WP_011790713.1\|3939820_3941185_+\|magnesium-transporter	gnl\|CDD\|225148	COG2239, MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism].	6.7894e-154
NC_008750.1\|WP_011790717.1\|3944760_3945618_-\|hypothetical-protein	gnl\|CDD\|224632	COG1718, RIO1, Serine/threonine protein kinase involved in cell cycle control [Signal transduction mechanisms / Cell division and chromosome partitioning].	3.09423e-69
NC_008750.1\|WP_011790714.1\|3941297_3942122_-\|molybdate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270259	cd13541, PBP2_ModA_like_2, Substrate binding domain of molybdate-binding proteins;the type 2 periplasmic binding protein fold. This subfamily contains domains found in ModA proteins of putative ABC-type transporter. ModA proteins serve as initial receptors in the ABC transport of molybdate in eubacteria and archaea. Bacteria and archaea import molybdenum and tungsten from the environment in the form of the oxyanions molybdate (MoO(4) (2-)) and tungstate (WO(4) (2-)). After binding molybdate and tungstate with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ModA proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.40959e-120
NC_008750.1\|WP_011790711.1\|3938051_3938495_+\|PTS-IIA-like-nitrogen-regulatory-protein-PtsN	gnl\|CDD\|182818	PRK10896, PRK10896, PTS IIA-like nitrogen regulatory protein PtsN.	7.54197e-61
NC_008750.1\|WP_011790723.1\|3954383_3957467_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_008750.1\|WP_011790724.1\|3957575_3958421_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.00215186
NC_008750.1\|WP_011790715.1\|3942356_3943043_-\|OmpA-family-protein	gnl\|CDD\|182507	PRK10510, PRK10510, OmpA family lipoprotein.	2.56889e-83
NC_008750.1\|WP_011790722.1\|3953300_3954380_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	3.56647e-65
NC_008750.1\|WP_011790725.1\|3958489_3959173_-\|LysE-family-transporter	gnl\|CDD\|236665	PRK10229, PRK10229, threonine efflux system; Provisional.	3.66604e-30
NC_008750.1\|WP_006083073.1\|3939332_3939608_+\|HPr-family-phosphocarrier-protein	gnl\|CDD\|376329	pfam00381, PTS-HPr, PTS HPr component phosphorylation site.	7.1011e-28
NC_008750.1\|WP_011790716.1\|3943681_3943915_+\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.000112206
NC_008750.1\|WP_011790727.1\|3960284_3962321_-\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	1.78223e-34
NC_008750.1\|WP_011790719.1\|3948600_3950238_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NC_008750.1\|WP_011790710.1\|3937761_3938049_+\|ribosome-hibernation-promoting-factor	gnl\|CDD\|182484	PRK10470, PRK10470, ribosome hibernation promoting factor.	1.13465e-33

>NC_008750.1|WP_011790718.1|3945975_3946524_+|DUF2799-domain-containing-protein
MRYLNLTLALCALSLTHCTSLSLEECSSSDWYTLGLADGNRGATATRLNQYQKDCNEFNLKVDASQWQQGYQQGLINYCLPENGYRVGLEGESYYGVCSDNQFVERYNQGHQQYLVNKRLAEIADRLHTIDSEISSINTKLNNLTDKADLLRQKNILLNEKNHLLDEKARLRQGNIEFKFRF
>NC_008750.1|WP_011790717.1|3944760_3945618_-|hypothetical-protein
MKTPKRIQPLVDEGLVDEVISQLMSGKEATVYVVRSGDDIRCAKVYKEADKRSFKQAVLYQEGRKVRNSRRARAMEKGSKFGRDQMEEAWQSAEVDALYRLADAGVRVPIPYGCFDGVLLMELVTDAEGNVAPRLNDVTLSAEKAIRDHNLVMTYVKRMLCAGLVHGDLSEFNVLVDSEGPVIIDLPQAVDAAANNHAKWMLARDINNMTQYYGQYAPELLKTQYAKEMWALFEAGDLKPDTQLTGEFTEVLAEADVGSVLEEIQAAYEEAQERKLRIQEANEDY
>NC_008750.1|WP_011790716.1|3943681_3943915_+|transposase
MGIADNNLKLDVIAEVKVKGRLLSDVAHQYGISAKAVYQWVRESDQQPQQREYALISEIAQLQKRIKQLNNELRTLG
>NC_008750.1|WP_011790715.1|3942356_3943043_-|OmpA-family-protein
MKRFQVNRFTSSRLAFAAIIGTFVVSGCSTVNPYTNEQQTAKATSGAIIGAVAGAAVGVASSSKSDRGKGALIGAASGAAVGGGIGYYMDVQETKLRQQLASTGVSVTRNGDNIILNMPNEVTFGVDQTELSDGASRVLNSVALVAKEYSKTQLNVLGYTDSSGSDAYNLRLSQVRASEVANYLMSKGIAASRVKSKGMGKASPIASNASAEGRAQNRRVEIVLTPTG
>NC_008750.1|WP_011790714.1|3941297_3942122_-|molybdate-ABC-transporter-substrate-binding-protein
MMKKNILVALSFCPAMMVSIVQGAPVTAEVAPIELRAAGSLKAAMNDIITAYQAQTKDTVVAQYAPSGLLLKRIQEGERVDLFASANMAHPQALVDAGFGEKVQMFARNQLCAIAQNSVSLTSATLLDTLLDPNIKVGTSTPKADPAGDYAWAVFDKAQTLKPDAKAILEAKALQLTGGPDSAKPPKDRNPYGWVMENKQADIFLTYCTNAVLAKNEVPSLQIIDLPTSLAVGADYGLLILKESNASAAPLAEFILSAKGQAILSRYGFQPPVN
>NC_008750.1|WP_011790713.1|3939820_3941185_+|magnesium-transporter
MPVEASDSHQVGHRLDQLSKALSSGMFVHVRQMLQNMAASDIALILESSPPKARQVLWQLIDQEQLGAILDELSEELKDPLISTMSPERVAKATASMDTDDLAYILRSLPDTVYKQVLQSMSLQNRQRVEQALSYPDETAGSLMNTDTVTLRPDVNIDVVLRYLRQRGNLPDTTDTLYVVDKQDKVLGGVRLADLLTCDPNTPIRNIMDPDIESIPVGMSDSEVAQLFERHDWVSAPVVDSDNKLLGRITIDDVVDVIREDAEHSMMGMAGMDDDEDTFAPVLKSTFRRSLWLTINLFAALLAASVSSMFEGTIEKFATIAILMTIVPSMGGVAGNQTLVLVIRAIALGHIGQSNARWLIGKELAIGFLNGLLWSILVFVAVSLWKGDTALASLIAGAMLINMTVAGLAGASIPLILKRLKIDPALAGGMVLTTVTDVTGLFAFLGLATLYLMN
>NC_008750.1|WP_006083073.1|3939332_3939608_+|HPr-family-phosphocarrier-protein
MPKLERQITICNKLGLHARAATKLVVLASEFDATITLIQGDKQASAASVLGLLMLETGMGKTIKLIAEGPDAEPALDAICALIDAKFDEAC
>NC_008750.1|WP_011790712.1|3938491_3939346_+|RNase-adapter-RapZ
MKLVIVSGRSGSGKSVALRVLEDLGYYCVDNLPLPLIGSLLEQLKGSNDLVAISVDVRNMPEQDKVLVQQLSNLPAGTEITSFFLNSSDKVLLKRYSETRRLHPLSKSRVSLQEAIKLEGKLLEPMSKLVDHYIDTSNLNIYDLSDQVRQILLGSVDKELVIYFESFGFKNGMPTEADFMFDVRFLPNPHWELALRPLTGLDEPVAEFLNRQPLVNKFIWQIENLLETWLPHLERNNRSYLTIAIGCTGGQHRSVYVAEQLAKRFSNGKHKVNVRHRELDHAKA
>NC_008750.1|WP_011790711.1|3938051_3938495_+|PTS-IIA-like-nitrogen-regulatory-protein-PtsN
MELCTILRPECTTCATPGSKKKVLELISDLAAAQYPTLSSQEIFESLVAREKMGSTGIGNGIAIPHGRLTDITQPIAILVKCEEPIAFDAIDKQPVDILFALLVPADQCQQHLSTLSCMAEKLSDKQILKQLRKTHDETELYQVITG
>NC_008750.1|WP_011790710.1|3937761_3938049_+|ribosome-hibernation-promoting-factor
MQIKLIGHHIEITESLRAYVEEKFSKLERHFEQIHNVHVVLNVEKMQQIAEARINLTGGEVFATSEHTDMYAAIDVLIDKLDRQVIKHKEKLTKH
>NC_008750.1|WP_011790719.1|3948600_3950238_-|chaperonin-GroEL
MAAKEVVFGNDARVKMLAGVNILANAVKVTLGPKGRNVVLDKSFGSPLITKDGVSVAKEIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIVTEGLKAVAAGMNPMDLKRGIDKAVIAAVAELKALSQPCADSKAIAQVATISANSDESIGEIIATAMEKVGKEGVITVEEGQALENELDVVEGMQFDRGYLSPYFINKPETGSVELDHPFVLLVDKKISNIRELLPILEGLAKTGKPLLIVAEDVEGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAMLQDVAILTGGTVIAEEIGLELEKATLEDLGTAKRVVITKDNTTIIDGNGEQAQIEARVSQIKQQIEESTSDYDKEKLQERMAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGVVPGGGVALVRVASKIAELEVLNEDQKHGVVIALRAMEAPLRQIATNAGEEASVVANTVKNGSGNYGYNAGNDTYGDMLEMGILDPTKVTRCALQFAASIAGLMITTEAMVAEIPQNSAPDMGGMGGMGGMGGMM
>NC_008750.1|WP_006086113.1|3950295_3950586_-|co-chaperone-GroES
MNIRPLHDRVIVKRLEVESTSAGGIVLTGSAAEKSTRGEILAVGNGRILENGTVKPLDVKVGDVVIFNEGYGVKKEKIDGQEVLILSEADLMAVVG
>NC_008750.1|WP_011790720.1|3950811_3952182_+|MATE-family-efflux-transporter
MKDRHGLLTAPIGRVLLNMSLPNLIGIMTILGFSLADTFFISQLGTEPLAAISFTFPVTLIISSIAIGIGAGVSTNLGRLIGSGNAPKAKVFLHDALLLTFILTASLSALGSIFITPLFSLLGANESSLPLIRDYMIYWYLAAPLLVVLMVGNQGLRSTGDTRSPAMIMSLAAIINLILDPLLIFGIGPFPRLEIQGAAIATLIAWVVALSLSSYLLIIKRKMLEWAAFDIDRMRANWSKLAHIAQPAALMNLINPLANAVIMAMLAHIDHSAVAAFGAGTRLESVLLIVVMALSSSLMPFIAQNLGAGQPQRAKEALLLSLKFIFIFQTLLYIPLVFLAEPIAHLFSTDPQVLEWLSFYILVLPCAYGPLGIVIIFATALNAYHRPINSLVINLCRLVLLMLPLAALGSYIGGVKGLLLALPVTNILMGIACYWLAQQICEPVKVTTVNANSATH
>NC_008750.1|WP_011790721.1|3952184_3953174_-|LysR-family-transcriptional-regulator
MKTEDLALFHRIAETGSLIEAADLLNLPKSTVSRRLQALEDELNIKLFHRQSRSMTLTSAGSHFYLRSQNILAQLDETLFEMTNDDAEISGHLRIQMFPIHSMKILMQAIFRFMDMHPKLTVEVISSAESVDMVKHNLDVAFVVEPALDTLDLVVRPIFTTDLRFYASPEYLAAHGIPKTPQEIESHNVSLFRLSNGKIFNELWIGLEEEVRVRGNFCSNSVEVAVEFALQGRGIVYAPTEVVAEFVETGELVTLLPEIDAHQGECFLAYPSRRYVSLASRRFIDFIMQELVPNGVPTNMSEMSTRRTCKVSKEAFPHDDLRFRIKESV
>NC_008750.1|WP_011790722.1|3953300_3954380_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MTSYRLLPLAALLPALLSGCSPAESSVQTPAVRPVKLFEVIQLEGGDFRTFPARVAANSRAELSFRISGQLTELALVEGQKVTEGSLLAKLDDRDAYNNLMTREADHELLAADYQRKVELLNRKLISQAEFDSTQAQLKSAKAALAAARDQLSYTRLTAPFSGTIAKRLVDNHQIVQANQGVLTLQNNNLLDVSIHVPEAMAAGLNEYIKQKNFTAKVRFTALEGMEFDAKFKEYSTQVTPGTQAYEVVFSLPQPSNVQLLPGMSAELTLALVKAPNQISAIVPVTAIDKRDQDGQVQVWVYQTQSGEVVPAPVTLGRVTNQGIEILGGLNKGDLIVSAGVSQLSTGMKVKPLRWQRGV
>NC_008750.1|WP_011790723.1|3954383_3957467_+|efflux-RND-transporter-permease-subunit
MNIAEYSIRHKVISWMFVLLLLIGGGISFTGLGQLEFPEFTIKEALVITAYPGASPEQVEEEVTLPLEDALQQLDAVKHVTSINSAGLSQIQIEIKDSYDKTSLPQVWDEVRRKVNDTAGQLPPGTGTPQVMDDFGDVYGILFNLSGPDYSNRELSNYADYLRRELVLVPGVKKVSVVGSITEQVVIEISQQKLSALGLDQSYIYGLINNQNVVSNAGSLVIGDNRIRIHPTGEFGSIQDLARLIVSPPGSTELIYLGDIANIAKDYNETPTVLYHNKGEAALSLGISFSSGVNVVEVGQRVSERLTELESQRPIGMNLDTVYNQSSAVDDTVNGFLINLLESIAIVIAVLLLFMGLRSGLLMGLILLLTILGTFIVMKVLGIELQLISLGALIIALGMLVDNAIVVTEGILIGLRRGKTRLEAAKQIVSQTQWPLLGATIIAIIAFAPIGLSQNASGEFCRSLFQVLMISLFISWITAITLTPFFCHLLFKDAPSDDEQDPYKGWVFNLYRASLTLALRFRIVSILLVGVLLVSAVIGFGHIKNVFFPASNTPIFFVDIWMPEGTDIKATERFAADIEQQLLKQAEQQHTGLTHLTTVIGQGAQRFILPYQPEKGYPAFAQLIVEMQDLEAVKNYMPELERFLNQRFPQAQYRLKNMENGPSPAAKIEARFYGDDPEVLRALGAQVEAIFYAEPSMDGIRHDWRNQVPLVRPQLENAQARETGISKQDLDNALLVNFSGKQIGLYRETSHLLPIVARAPAEERLQADSLWKLQIWSSEHSTFVPATQVVSNFNTEWENPLVMRRDRMRMLAVLADPKLGSDETADSVLRKVKDKVEAIALPAGYHLEWGGEYETAGEAQTAVFSSIPLGYLAMFLITVFLFNSVRQPLVIWFTVPLALIGVSAGLLLFDAPFSFMALLGLLSLSGMVIKNGIVLVDQINLELSEGKAAYSALLDSCVSRVRPVMMAAITTMLGMIPLISDAFFGSMAITIIFGLGFASVLTLIVLPVMYSLAFNIKPTLIGGQSRN
>NC_008750.1|WP_011790724.1|3957575_3958421_-|nuclear-transport-factor-2-family-protein
MAQVLWIIQIISKGLVRTLRFKAHILRMILLGSLGVAIHVSVVNAAVTDNSLPQESIPLVQGFIDAAKAHDRQAIADYMAYPIKRTNPIPAINTPEELLKRFDQVFDPEILETIAQSQVEADWQAMGWRGIMLGSGTIWMDFDGKITAVNYQTPAETKLKAELIANQKTGLHESVSQFVSPELAWQTAKFTIRVDNMGNSQYRYASWAKGKPLSEKPDLVLNQGKLVFDGSGGNHSFQFTSGPYLYVCDVIVLGTSDSPIGELVVFKHDRVLLREPAIKAE
>NC_008750.1|WP_011790725.1|3958489_3959173_-|LysE-family-transporter
MDLSLLLTLALIHAVALVSPGPDFAIMVKIATQQSRSAAVAAAVGISVAIVAHTILSLTGVSLVIKSSHTLYLLVQIIGACYLAWMGWGALRAAFAVLATPKGSQGVNDSGMAGSAVTPVPLGTTMSPKQGFLTGLYTNLLNPKALVFFLTLFSALITPSVTVSTKVAAAMLLLLLSLLWFGFLALMLSKAQVQRKLQRLTPVIDTVIGVIFIVVAFAIVSSLLFSA
>NC_008750.1|WP_011790726.1|3959282_3960113_-|AraC-family-transcriptional-regulator
MSTTASIENIDYWRHPSLSGIELSQAEFTHFSFDKHVHLDYHLGVVTQGAQQFVNKGSYYQLGQHSLSTLNPDDTHDGQSRDAEGYRVKVMSIPVEYMNEVSQELGLKEHFFSAPMVDDALLYHYFIHLHELLIQGQVTALASESHLFNFIQLLLRRHPSGILKCNSPQGLSTLQLGLVKQRMHDEPWHNTQLETLAGEVNLSKFQFLRQFKQATGMTPHAYLKRVRLELAKKSLCHGTLVADVAQQLGFFDQSHLNKAFKQAFLLSPVQFQRRML
>NC_008750.1|WP_011790727.1|3960284_3962321_-|TonB-dependent-receptor
MKLAVCFLPLLGLSYTVIAEDLADNIERLEIRGRQINTLGHSTSASEGIVGAAEIASRPLLRTGEILEFVPGMIVTQHSGSGKANQYFLRGFNLDHGTDFNTRVEGMPVNMRTHGHGQGYTDLNFLIPELLGEIRYAKGAYYPEVADFSGAGAAQLMLADQLAYNQVGVTLGEYGYQRLVATQALTTDVGRFILGVELQAYDGPWKDINEDVSKVNVVARYLTRLAGGDLSVTMMAYDNSWNSADQIPARAVESGLIDFYGSLDKDVGGDASRYSVSAHYDAGNWQGNAYAIRSTMDLFSNFTYFLNDPVNGDEFEQVDERTLWGGDIKRDWHTSLGGTQINYSLGADIRYDDISAVGLYNTQARQRLSTVRLDEVQELSGGLFGKLEWLPLEQWRFNLGLRYDYFDVQVDSDNSLNSGDASDGMLSLKAGASYLWSDNLELYVNAGQGLHSNDARGATIKVDPVSGDEVDKVDLLVRSNGGEFGVKYYNRDFINFSAAVWYLQLDSELVFVGDAGNTEPSRASERYGAEITAYYWLNDDISLDMELAWTHARFTEDEAEEGKYIDGAVPFVGSAGITYRPDGGLYSSIRIRYLGERVLDNFNEHKADDTTLVNLALGYKFDHFDTKLELLNLFDSQDHDIDYFYASRLPGEAAEGIEDQHYHPVEPRMIRVSVSYHF

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Crispr_ID: NC_008750_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008750_7

4292948-4293036

Orphan

Consensus_repeat	Method
CAAAAAGCTGGATCCCCGCTCAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008750_7

>merge|NC_008750|7|4292948-4293036|CRISPRCasFinder
CAAAAAGCTGGATCCCCGCTCAAATGCAGTGCGGGGATGACGATGCTTAATCAAACTTCAGTTATCAAAAAACTGGATCCCCGCTCAAA

>NC_008750|7|7|4292948-4293036|CRISPRCasFinder
CAAAAAGCTGGATCCCCGCTCAAA	TGCAGTGCGGGGATGACGATGCTTAATCAAACTTCAGTTAT
CAAAAAACTGGATCCCCGCTCAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008750.1\|WP_011790985.1\|4292258_4292879_-\|hypothetical-protein	unknown	unknown	unknown
NC_008750.1\|WP_011790982.1\|4288665_4289541_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226830
NC_008750.1\|WP_011790988.1\|4296051_4297911_-\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|237104
NC_008750.1\|WP_041408261.1\|4290095_4290278_+\|hypothetical-protein	unknown	unknown	unknown
NC_008750.1\|WP_041408472.1\|4294438_4296034_-\|threonine-ammonia-lyase,-biosynthetic	unknown	unknown	gnl\|CDD\|236417
NC_008750.1\|WP_041408262.1\|4290267_4291068_+\|hypothetical-protein	unknown	unknown	unknown
NC_008750.1\|WP_081429810.1\|4300067_4300157_-\|leader-peptide-IlvL	unknown	unknown	unknown
NC_008750.1\|WP_011790984.1\|4291692_4292211_-\|DUF4303-domain-containing-protein	unknown	unknown	gnl\|CDD\|372922
NC_008750.1\|WP_011790979.1\|4284229_4285639_+\|ammonia-forming-cytochrome-c-nitrite-reductase-subunit-c552	unknown	unknown	gnl\|CDD\|236854
NC_008750.1\|WP_011790986.1\|4293064_4294198_-\|alanine--glyoxylate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223153
NC_008750.1\|WP_011790992.1\|4303087_4304404_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NC_008750.1\|WP_011790981.1\|4287662_4288472_+\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|182658
NC_008750.1\|WP_011790990.1\|4300507_4301986_-\|ketol-acid-reductoisomerase	unknown	unknown	gnl\|CDD\|235368
NC_008750.1\|WP_011790977.1\|4282515_4282872_+\|hypothetical-protein	unknown	unknown	unknown
NC_008750.1\|WP_011790978.1\|4283034_4284246_+\|NnrS-family-protein	unknown	unknown	gnl\|CDD\|377571
NC_008750.1\|WP_083758279.1\|4298222_4299881_-\|acetolactate-synthase-2-catalytic-subunit	unknown	unknown	gnl\|CDD\|181601
NC_008750.1\|WP_041408474.1\|4302218_4303091_+\|HTH-type-transcriptional-activator-IlvY	unknown	unknown	gnl\|CDD\|236961
NC_008750.1\|WP_011790993.1\|4304941_4305352_-\|YkgJ-family-cysteine-cluster-protein	unknown	unknown	gnl\|CDD\|223799
NC_008750.1\|WP_011790980.1\|4286090_4287569_+\|cell-envelope-integrity-protein-CreD	unknown	unknown	gnl\|CDD\|236960
NC_008750.1\|WP_007651625.1\|4297968_4298226_-\|acetolactate-synthase-2-small-subunit	unknown	unknown	gnl\|CDD\|236862

Protein	Function_ID	Function_description	E-value
NC_008750.1\|WP_011790982.1\|4288665_4289541_-\|hypothetical-protein	gnl\|CDD\|226830	COG4395, COG4395, Uncharacterized protein conserved in bacteria [Function unknown].	1.55928e-39
NC_008750.1\|WP_011790980.1\|4286090_4287569_+\|cell-envelope-integrity-protein-CreD	gnl\|CDD\|236960	PRK11715, PRK11715, cell envelope integrity protein CreD.	0
NC_008750.1\|WP_011790993.1\|4304941_4305352_-\|YkgJ-family-cysteine-cluster-protein	gnl\|CDD\|223799	COG0727, COG0727, Predicted Fe-S-cluster oxidoreductase [General function prediction only].	8.74539e-11
NC_008750.1\|WP_011790988.1\|4296051_4297911_-\|dihydroxy-acid-dehydratase	gnl\|CDD\|237104	PRK12448, PRK12448, dihydroxy-acid dehydratase; Provisional.	0
NC_008750.1\|WP_041408472.1\|4294438_4296034_-\|threonine-ammonia-lyase,-biosynthetic	gnl\|CDD\|236417	PRK09224, PRK09224, threonine ammonia-lyase IlvA.	0
NC_008750.1\|WP_011790990.1\|4300507_4301986_-\|ketol-acid-reductoisomerase	gnl\|CDD\|235368	PRK05225, PRK05225, ketol-acid reductoisomerase; Validated.	0
NC_008750.1\|WP_011790984.1\|4291692_4292211_-\|DUF4303-domain-containing-protein	gnl\|CDD\|372922	pfam14136, DUF4303, Domain of unknown function (DUF4303). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 169 and 192 amino acids in length.	2.09583e-18
NC_008750.1\|WP_011790979.1\|4284229_4285639_+\|ammonia-forming-cytochrome-c-nitrite-reductase-subunit-c552	gnl\|CDD\|236854	PRK11125, nrfA, ammonia-forming cytochrome c nitrite reductase.	1.87869e-163
NC_008750.1\|WP_011790986.1\|4293064_4294198_-\|alanine--glyoxylate-aminotransferase-family-protein	gnl\|CDD\|223153	COG0075, COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism].	3.60241e-155
NC_008750.1\|WP_011790981.1\|4287662_4288472_+\|phosphatase-PAP2-family-protein	gnl\|CDD\|182658	PRK10699, PRK10699, phosphatidylglycerophosphatase B; Provisional.	1.2344e-35
NC_008750.1\|WP_011790978.1\|4283034_4284246_+\|NnrS-family-protein	gnl\|CDD\|377571	pfam05940, NnrS, NnrS protein. This family consists of several bacterial NnrS like proteins. NnrS is a putative heme-Cu protein (NnrS) and a member of the short-chain dehydrogenase family. Expression of nnrS is dependent on the transcriptional regulator NnrR, which also regulates expression of genes required for the reduction of nitrite to nitrous oxide, including nirK and nor. NnrS is a haem- and copper-containing membrane protein. Genes encoding putative orthologues of NnrS are sometimes but not always found in bacteria encoding nitrite and/or nitric oxide reductase.	1.05018e-96
NC_008750.1\|WP_041408474.1\|4302218_4303091_+\|HTH-type-transcriptional-activator-IlvY	gnl\|CDD\|236961	PRK11716, PRK11716, HTH-type transcriptional activator IlvY.	0
NC_008750.1\|WP_007651625.1\|4297968_4298226_-\|acetolactate-synthase-2-small-subunit	gnl\|CDD\|236862	PRK11152, ilvM, acetolactate synthase 2 small subunit.	1.54179e-33
NC_008750.1\|WP_011790992.1\|4303087_4304404_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.85458e-133
NC_008750.1\|WP_083758279.1\|4298222_4299881_-\|acetolactate-synthase-2-catalytic-subunit	gnl\|CDD\|181601	PRK08978, PRK08978, acetolactate synthase 2 catalytic subunit; Reviewed.	0

>NC_008750.1|WP_011790985.1|4292258_4292879_-|hypothetical-protein
MSINPQAFFIVQSDPDGKGIPYFMDKNWTPELPDYEIYDSPPCEGDFLTAYSLKAKAYQLNGDYLVDENLVSNEMLCLCEKLNVKCIRIPVDINLYRGVRPQKKYFLFFPLSYLSILDKDESIYTISIDLDSGKLNTQEERGLKKTYYESIDKFKIKNNICEHLFFCNEIAASVCSIQFKNEYEALGLTGVSFKEINEHYQYSAWD
>NC_008750.1|WP_011790984.1|4291692_4292211_-|DUF4303-domain-containing-protein
MDWIELEEKCFETTYDIIKMLLLENKDETFYAVSLYTDSSAMSVSLSASSEEKLKSILADEEEQSIECESYYRWAVSEWFYDGYNAGAFSKISKMLREDSSREINFAKFKSELIQTLSNVLVRIKRELPIELHSTVCFVSVTDDNESEEIENSSAKLINDAPLSMAFISRFD
>NC_008750.1|WP_041408262.1|4290267_4291068_+|hypothetical-protein
METNQTQKSGSNSVNVQTQNLNISNGLSYSEAKEVAQDVFDRNFYRLSNTAREIAENRASELVNDFLHNLHINSPIISGSINDPDFQYVLFEAQKQYARNGNVQIKELLVNVLTKRINTPSKLEIVICNEAINSISKLTNNQLVALELIYTLTVQKPSDLAVNVKEHLIKYVLPIANKIKIETTDLEHLLYASCCNKESIKNHLADIYQKAFPQEFTSHDPNGYIILQCPDIGLLFPLWHSSIFCQLSLTSVGKYIGQLLSETENF
>NC_008750.1|WP_041408261.1|4290095_4290278_+|hypothetical-protein
MSWFIENKEWLLSGAAISIPIAVIGWIKACKSTKQLQKSGHNSVNIQVGGNLKVGKKSGD
>NC_008750.1|WP_011790982.1|4288665_4289541_-|hypothetical-protein
MKKLFIMLAMIFAVSLVTSPVVEAKKFGGSKSIGKSHQTAPAQPAATNTPTTAPAGAPGKKGMMGGMLGGLLAGGLLAALFMGEGFENIQFMDILIIGLLAFVLFKIVRTVMASKAGAQPRPAYAGAGQPNPNFQRQQAEQTGFASNATNNANSGSHGFAQAASDVPFNLPAGFDLPGFLEGARSHYKTLQLAWNENDLSKIQEYVSIELFNELSNQRRELVGDQHTEVMFLDAELVRATHTANLAEVSVKFSGRYRDTVEGVEEDIKEVWHLERNVAQANSPWLIVGIEQ
>NC_008750.1|WP_011790981.1|4287662_4288472_+|phosphatase-PAP2-family-protein
MVFYKEAFILTHRANLFCRLGLAWLLLATIPSLLLLTQNQLFPLIDLHSTFARMLYWITTTGTAPYGVATVLFVLAIAYRLMPKPLFISLFLAISISQVISLSLSHTLKSFFKEPRPNVVFLTEQALPIDEQLSLDAFYQLDKQTRSKTIANALDGLIATDPTMKLDSRIHQHWEDEVGYSFPSGHTIFAATLVLTASYYLLCAGLPMFAILLLGWGLLMGLSRMLLGMHWPQDVLFSTLLASVISWVSVLLVDKLRPLSSYVIKDAHK
>NC_008750.1|WP_011790980.1|4286090_4287569_+|cell-envelope-integrity-protein-CreD
MFSIIFWVLTLLSLALFGAAAYFVVRALLKKFNRDQGIDMSAQDPWAAATAKGTALKNTTLLKALTIGILSIIALIPLGIIMDMTSDRQALYHSVVDEIGRSWGEQQTLSGPVLVIPYSYFVLQEEVSNDGKTRHEVKRTYQDELVILPKKLTLDLDLKHDFRTRGIYQSLVYNAALQGQADFSLNRYDIPNLIAFDNKNARLVFGVSSNQAIDKVEKIEITGDSTLLSGSLMSGTGLTTGGLEKGFNQRLQVGEASDFSVNFAMTLRGSQSISALPLGEQTLINIQADWPHPSFKGLLPAERKISANGFTASWNISHLTRNYPQEFIKSSQSTLTEVVANAMLFEPVTHYGKIERSVKYGLLFIVLTFIMLFIFELGQKTSLSTIQYVLVGSAMALFYLLLLSLSEHLAFLHAYLIAACIPVLSVSAYVGSATTSMKRGSIVGLMLVSLYAVLYSILQLEDYALLMGTGLLLVILLILMFVTRHQAKNTAQ
>NC_008750.1|WP_011790979.1|4284229_4285639_+|ammonia-forming-cytochrome-c-nitrite-reductase-subunit-c552
MGAQVNIDVLTKGYKVKIYLKTVILLKLIGFLVIATCTSVAASDTSNQQKYPNQYQSWQATSEQVEREDMLANYPASIILWAGSSYAKEYHSPRGHHFAVADVTQTLRTGVPPKAGEKGLSASCWTCKTPDAPRLIEQLGFEGYSAKNFTDLGKEIQSVVYCSDCHESGTQKLALPRPHAQDAMAKVHLPFDKQDKNMQGAQVCGQCHVTYYFRPEKSNVVNIPWIFGSTADDIEKYYDTRRFFEWIHPISKTPILKARHPEFEHWSRSKHAEVGVTCITCHMPTQQDAKGVEFTSHKVDKALPHFDSSCSGCHSSKTKIETKLAANKLTIETKAREVESLLVKAHYEAKAAWDAGAKWEQMNEPIMAIRHSQWRWDFAMSSHGLYAHNPEEGKQLLDKAIEQANDARNQLASVLKHFKVIQVSYPDISTKEKAQQAIGLVEADLIKEKQKFIEDEVNKNWHPVAKYGY
>NC_008750.1|WP_011790978.1|4283034_4284246_+|NnrS-family-protein
MLNIDDPKQTERTHALWRLGFRPFFLGGAIIAALYIPLWLLTWFTPQYSFFAPSFWANILPLWWHPHEMLFGFAMAIVCGFLLTAVQNWTNQPTLKGWPLALTFSCWLLARLLLLLPMQIPLILPALFDSLFLGMASFTLWRCIYKVKQWRNIGFPIMLFAALVINNVSYYALFERDFILANQIWQAMLWWLALLITIVAGRVIPFFTAMRIKATKANPLPWIEYPLLLAMILLVIQALTHLIPQEIERSLLLIAGLLQLVRFARWLPHKTLKEPMLWSLHIAYLMLPISLLAMSWYLDNEYAYRSLLHLFAIGCMATLCLSMISRVSLGHTSRNIYEGPKMILAFICLPLAALLRALMPIWFPAHTQVWLWLAASCWFIAFALFVWHYLPILTRPRIDGRPG
>NC_008750.1|WP_011790977.1|4282515_4282872_+|hypothetical-protein
MVLSMEMTTYDMSTWENIASWVLLLLGGLPLLIYPFVVFANLMLLAGHKSTYKPPLFNRLMNQGFIWGSFIYPAIYIPLYKIAIQLQSNQTLIYAALPVAYLALLAVCFRYMNAPLKP
>NC_008750.1|WP_011790986.1|4293064_4294198_-|alanine--glyoxylate-aminotransferase-family-protein
MLPAPRFTAFNPPRRILMGPGPSDVYPEVLAAQSRPTVGHLDPLFVGMMDELKSLIQYAFQTKNEMTMAVSAPGSAGMETCFVNLVEPGEKVIVCRNGVFGERMRQNVERMGAIAVLVDNEWGTPVDPAAVEAALKANPDAKFLAFVHAETSTGALSDAKTLCALAKTYGCLSIVDAVTSLGGVELRVDEWGIDAIYSGSQKCLSCVPGLSPVSFSPAAVEKLKNRKTPVQSWFLDQSLVMAYWASAGGKRSYHHTAPVNALYALHESLRMLAAEGLENAWQRHHDMHLVLRAGLEKLGLNFVVAEDSRLPQLNAVYIPAGVDDAAVRARLLKDYNLEIGAGLGALAGKAWRIGLMGFGARRENVALCLKALEEVLS
>NC_008750.1|WP_041408472.1|4294438_4296034_-|threonine-ammonia-lyase,-biosynthetic
MLPLASQTQADLAHFQLAQSYLQKILLSSVYDIAKVTPLSSMNKLSARLGCQVFLKREDMQPVHSFKLRGAYNRIAQLTKEECQRGVVCASAGNHAQGVAMSAASRGVDAVIVMPETTPDIKIDAVRRLGGNVVLHGQAFDQANGFAMTMAKEEGRVYIAPFDDEAVIAGQGTIAQEMLQQQRDLEVVFVPVGGGGLIAGIAAYYKAVMPQVKIVGVEPEDAACLKAAMEAGEPVTLAQVGLFADGVAVKRIGTEPFRVAKLYVDEVVTVTSDEICAAVKDIFEDTRAIAEPAGALSLAGLKKYVSTNASGDCGNGEKVAAILSGANVNFHSLRYVSERCELGEQKEAVLAVKVPERPGSFLTFCELLDKRVMTEFNYRFSSRDLAVVFAGIRLSRGQGELEQIIATLEANGFEVQDLSGDETAKLHVRYMVGGHPPEPLEERLFSFEFPEHPGALLKFLTTLQSKWNISLFHYRNHGAAFGRVLAGFEVPASDALPFQQFLTELGFVYQEETQSPAYQLFLNAGNGNKAL
>NC_008750.1|WP_011790988.1|4296051_4297911_-|dihydroxy-acid-dehydratase
MPKLRSATSTEGRNMAGARALWRATGVKDNDFGKPIIAIANSFTQFVPGHVHLKDMGSLVASAIEEAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADALVCISNCDKITPGMLMAALRLNIPVVFVSGGPMEAGKTKLSDKLIKLDLVDAMVAGADSNVSDEDSAKIERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHADRRELFLEAGRRVMALAKRYYHQDDESALPRNIANFKAFENAMTLDIAMGGSSNTVLHLLAAAQEADVDFTMADIDRMSRLVPHLCKVAPSTPKYHMEDVHRAGGVMGILGELDRAGLLHTDVFHVAADEGGNLKSVLAKYDVMQTQDEKVKHFFMAGPAGIPTTKAFSQDCRWPSLDNDRQEGCIRSREFAFSQEGGLAVLSGNVAENGCIVKTAGVDESNLTFVGSARVYESQDDAVAGILGGEVVAGDVVVIRYEGPKGGPGMQEMLYPTSYLKSRGLGKACALITDGRFSGGTSGLSIGHVSPEAAAGGTIALIENGDRIEIDIPKRSIKLALTDAELAARREAMLARGPMAWKPIGRERFVSLALKAYAMLATSADKGAVRDRSKLED
>NC_008750.1|WP_007651625.1|4297968_4298226_-|acetolactate-synthase-2-small-subunit
MIHSLELTVQQRPEVLERVLRVTRHRGFRITQMQMRMNDDASLSLDMEVDSERAIELLSNQLNKLIDVTQCKVLLPLSLQQTANA
>NC_008750.1|WP_083758279.1|4298222_4299881_-|acetolactate-synthase-2-catalytic-subunit
MIRGADAVIKVLAAHGVTTVFGYPGGAIMPIYDALYGSPVEHLLSRHEQGAAFAAVGYARASGKTGVCFATSGPGATNLITSLADALLDSVPIVAITGQVSTAVIGTDAFQEIDVLGMSLSCTKHSFMVTDVNDLIPTLYQAFEIAASGRPGPVLVDIPKDIQLAHLEYRTPLLAVMNEPQAEMSDIEAARALLAEAKQPMLYVGGGVGMAGAVDQLREFIKVTGIPSVATLKGLGSIAHGTPGYLGMLGMHGGKAANLAVQDCDLLIVVGARFDDRVTGRLASFADKAKVIHLDIDAAELGKLRMPEVAIAGDLRQILPALAMSMNITPWQAEVEHLSRKHQWDYQHPGSLIYAPALLRRLANKLPEDNVVCCDVGQHQMWVAQHMWFRRPEDHLSSAGLGTMGFGLPAAIGAQVARPDATVVTVSGDGSFMMNVQELTTIKRRKLPVKIVLVDNQKLGMVKQWQQLFFEERYSETDLSDNPDFVLLASAFDIPGRTIFSSDEVEEALTEMLAAKGPYLLHVAIDDAFNVWPLVPPGASNSDMMDEMEKQT
>NC_008750.1|WP_081429810.1|4300067_4300157_-|leader-peptide-IlvL
MMFNQAAKLILVIITVVIIKSQRGRRMAN
>NC_008750.1|WP_011790990.1|4300507_4301986_-|ketol-acid-reductoisomerase
MANYFNSLNLRQQLAQLGQCRFMDRSEFTDGCNYIKDWNIVILGCGAQGLNQGLNMRDSGLNISYALRHEAIEQKRASWQKATDNGFRVGTFEELIPTADLVLNLTPDKQHSNVVNAVMPLMKQGATLSYSHGFNIVEEGMQVRPDITVIMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGDGLEIAKAYASATGGDRAGVLLSSFIAEVKSDLMGEQTILCGMLQTGAILGYEKMVADGVEPGYAAKLIQQGWETVTEALKHGGITNMMDRLSNPAKIKAFEIAEDLKEILQPLFEKHMDDIISGEFSRTMMEDWANDDANLLRWRAETGETGFENAPVSSEHIDEQTYFDKGIFLVAMIKAGVELAFDTMVSAGIVEESAYYESLHETPLIANTIARKRLYEMNVVISDTAEYGCYLFNHAAVPMLRDYVNAMSPEYLGAGLKDSSNSVDNLQLIAINDAIRHTAVEYVGAELRGYMTDMKSIVGA
>NC_008750.1|WP_041408474.1|4302218_4303091_+|HTH-type-transcriptional-activator-IlvY
MDIRTLKLYLHLCDSLHFAKTAEQMHVSPSTLSRALQRLEEEVNAKLLERDNRSVTLTHAGREFKLFAEQTLHHWSTLRHSIDLKQDVLRGRLNLYCSVTAAYSHLPHLLDLFRQEHPFVEIALTTGDAANALAEVQQNRADIAIAALPDPFPSSLHFAKIDDVPLSIIAPTIRCAVQQQVSQTPIDWSSVPFIIPDHGPGRRRADNWFKQMGISPNIYAQVSGQEAIASMVALGCGVSISPEVVINNSPVRDRIQLLTSPVTIPPFELGCCCKVKRLDDPILSAFLEVI
>NC_008750.1|WP_011790992.1|4303087_4304404_-|HlyC/CorC-family-transporter
MSIFDNVMIILCLIGASCFFSMSEIALAASRKIRLRQLADEGDGRAEKVLQLQAHPGSFFTVVQIGLNGVAIMGGIVGESAFRPYFYELLSPWLTGTWLSQVSFVLSFVLVTSAFILVADLMPKRIAMAMPEPVALAVVGPMSFCIALLRPLVWFFNGLATAIFKLLQIPTVRNDEITSDDIYAVMNAGAEAGVLDRGDQQMMENVFEMQTVSVTSAMTARESLVYFLLQDSEEDIKRKISEDPHTKFLVCDGQLDMVKGFVDAKELLIRVINGEDITLKDSSLVHTSLIIPDTLSLSEAMEYFKNSRADFAVVMNEYALVVGIVTTNDLQRAVMGAWSLHESEEQIIARDGNSWLVDGVTPITDVMRAFDIEEFPHNQNYETIAGFMMYMLRKIPKRTDFVNYAGYKFEVVDIDAYKVDQLLVTRIDSSDKQISPDT
>NC_008750.1|WP_011790993.1|4304941_4305352_-|YkgJ-family-cysteine-cluster-protein
MSKRGKSIVSAVSIFNIDDLSTWQKYRKGLCDTCHATCCTLPVEVRVSDLVRMALVDEFEAEGDLKSIAKRLQKARLIDHFNHKTAIFTLARMANDDCLYLDSHTRRCTIYHQRPETCRNHPQIGPKPNFCPYCPR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_008750_5	5.4\|2522786\|32\|NC_008750\|CRISPRCasFinder,CRT	2522786-2522817	32	NC_008750.1	2870037-2870068	1	0.969

1. spacer 5.4|2522786|32|NC_008750|CRISPRCasFinder,CRT matches to position: 2870037-2870068, mismatch: 1, identity: 0.969

accaaagcgattgctaaaatcacggctgtaca	CRISPR spacer
accaaaccgattgctaaaatcacggctgtaca	Protospacer
****** *************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_008750_6	6.15\|3947626\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947626-3947657	32	NZ_CP013115	Shewanella xiamenensis strain T17 plasmid pSx1, complete sequence	161595-161626	0	1.0
NC_008750_6	6.5\|3947026\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947026-3947057	32	MH648987	Siphoviridae sp. isolate ctcj11, complete genome	15657-15688	2	0.938
NC_008750_5	5.18\|2523626\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523626-2523657	32	MT074146	Bacteroides phage SJC03, complete genome	47320-47351	5	0.844
NC_008750_5	5.13\|2523326\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523326-2523357	32	AJ131519	Lactobacillus bacteriophage phi adh complete genome	5588-5619	6	0.812
NC_008750_5	5.13\|2523326\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523326-2523357	32	NC_000896	Lactobacillus prophage phiadh, complete genome	5588-5619	6	0.812
NC_008750_5	5.15\|2523446\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523446-2523477	32	MN693861	Marine virus AFVG_250M517, complete genome	16017-16048	6	0.812
NC_008750_5	5.22\|2523866\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523866-2523897	32	NC_047960	Enterobacteria phage vB_EcoS_IME347, complete genome	14975-15006	6	0.812
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	MN694200	Marine virus AFVG_250M858, complete genome	25733-25764	7	0.781
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	MH552526	Siphoviridae sp. isolate ctfj46, complete genome	79589-79620	7	0.781
NC_008750_5	5.10\|2523146\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523146-2523177	32	MT028491	Ochrobactrum phage vB_OspM_OC, complete genome	29842-29873	7	0.781
NC_008750_5	5.18\|2523626\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523626-2523657	32	MT586120	Synechococcus phage S-CAM7 isolate 0809CC03, complete genome	73249-73280	7	0.781
NC_008750_5	5.18\|2523626\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523626-2523657	32	NC_031927	Synechococcus phage S-CAM7 isolate 0910CC49, complete genome	72170-72201	7	0.781
NC_008750_5	5.18\|2523626\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523626-2523657	32	KU686213	Synechococcus phage S-CAM7 isolate 0910SB42, complete genome	73793-73824	7	0.781
NC_008750_5	5.18\|2523626\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523626-2523657	32	JX569801	Campylobacter phage CP30A, complete genome	84762-84793	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	FR671407	Streptococcus phage 34117	15735-15766	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KY065505	Streptococcus phage IPP69, complete genome	22340-22371	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KY065475	Streptococcus phage IPP35, complete genome	23439-23470	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KT337367	Streptococcus phage phiARI0826b, partial genome	12166-12197	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KT337344	Streptococcus phage phiARI0274b, partial genome	13491-13522	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	NC_031929	Streptococcus phage phiARI0468-1, complete genome	18071-18102	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KY065474	Streptococcus phage IPP34, complete genome	22141-22172	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KY065488	Streptococcus phage IPP50, complete genome	23474-23505	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	FR671405	Streptococcus phage V22	15161-15192	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KT337352	Streptococcus phage phiARI0460-1, complete genome	17706-17737	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	NC_024357	Streptococcus phage K13, complete sequence	17124-17155	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KT337349	Streptococcus phage phiARI0399, partial genome	17840-17871	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KY065500	Streptococcus phage IPP64, complete genome	22121-22152	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	FR671411	Streptococcus phage 2167	15106-15137	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KY065452	Streptococcus phage IPP10, complete genome	22166-22197	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KT337356	Streptococcus phage phiARI0468-2, complete genome	18399-18430	7	0.781
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	KT337340	Streptococcus phage phiARI0031, complete genome	19718-19749	7	0.781
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	NZ_LR214977	Mycoplasma cynos strain NCTC10142 plasmid 4	1758-1789	7	0.781
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	NZ_LR214977	Mycoplasma cynos strain NCTC10142 plasmid 4	4102-4133	7	0.781
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	919829-919860	7	0.781
NC_008750_6	6.10\|3947326\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947326-3947357	32	DQ288668	Vibrio phage CTX strain VCE232 CtxB (ctxB) gene, partial cds; and RS2 element RstR-like protein (rstR), RstA-like protein (rstA), and RstB-like protein (rstB) genes, complete cds	2966-2997	7	0.781
NC_008750_6	6.10\|3947326\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947326-3947357	32	NC_013596	Streptosporangium roseum DSM 43021 plasmid pSROS01, complete sequence	1403-1434	7	0.781
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP015253	Bacillus thuringiensis Bt18247 plasmid p113275, complete sequence	107702-107733	8	0.75
NC_008750_5	5.13\|2523326\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523326-2523357	32	NC_016748	Marinitoga piezophila KA3 plasmid pMARPI01, complete sequence	3225-3256	8	0.75
NC_008750_5	5.22\|2523866\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523866-2523897	32	AP014165	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C61-MedDCM-OCT-S33-C79, * SEQUENCING IN PROGRESS *	25059-25090	8	0.75
NC_008750_5	5.25\|2524046\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2524046-2524077	32	MN693424	Marine virus AFVG_25M201, complete genome	16550-16581	8	0.75
NC_008750_6	6.7\|3947146\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947146-3947177	32	NZ_CP030761	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence	953172-953203	8	0.75
NC_008750_6	6.9\|3947266\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947266-3947297	32	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	513975-514006	8	0.75
NC_008750_1	1.2\|1666371\|33\|NC_008750\|CRISPRCasFinder	1666371-1666403	33	MT774405	CrAssphage cr115_1, complete genome	59727-59759	9	0.727
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP014152	Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence	187873-187904	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP013710	Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence	91481-91512	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NC_010418	Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence	2207-2238	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	MG945261	UNVERIFIED: Microviridae sp. isolate 4002-1602, complete genome	3180-3211	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP023028	Acinetobacter baumannii strain 10042 plasmid pAba10042b, complete sequence	84373-84404	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	MK531538	Acinetobacter baumannii strain MC23 plasmid pMC23.1, complete sequence	62828-62859	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_KY022424	Acinetobacter baumannii strain Ab8098 plasmid pAb8098, complete sequence	23668-23699	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP035052	Acinetobacter baumannii strain ABUH763 plasmid p74.1Kbp, complete sequence	69476-69507	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NC_025111	Acinetobacter baumannii strain D72 plasmid pD72-2, complete sequence	65487-65518	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP016302	Acinetobacter baumannii strain CMC-CR-MDR-Ab66 plasmid pCMCVTAb2-Ab66, complete sequence	35207-35238	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP016297	Acinetobacter baumannii strain CMC-CR-MDR-Ab4 plasmid pCMCVTAb2-Ab4, complete sequence	36102-36133	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP033857	Acinetobacter sp. FDAARGOS_493 plasmid unnamed1, complete sequence	53595-53626	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP050392	Acinetobacter baumannii strain VB11737 plasmid pVB11737_1, complete sequence	65485-65516	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP050413	Acinetobacter baumannii strain PM192696 plasmid pPM192696_1, complete sequence	65483-65514	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP050404	Acinetobacter baumannii strain VB2486 plasmid pVB2486_1, complete sequence	94475-94506	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_LT984690	Acinetobacter baumannii isolate K50 plasmid I, complete sequence	74983-75014	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP029571	Acinetobacter baumannii strain DA33098 plasmid pDA33098-71, complete sequence	67052-67083	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP023030	Acinetobacter baumannii strain 9102 plasmid pAba9102a, complete sequence	7310-7341	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP023030	Acinetobacter baumannii strain 9102 plasmid pAba9102a, complete sequence	85924-85955	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP050909	Acinetobacter baumannii strain DT-Ab022 plasmid unnamed2, complete sequence	66579-66610	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP008707	Acinetobacter baumannii strain AB5075-UW plasmid p1AB5075, complete sequence	78995-79026	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP023033	Acinetobacter baumannii strain 7847 plasmid pAba7847b, complete sequence	55148-55179	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	CP014292	Acinetobacter baumannii strain AB34299 plasmid unnamed1, complete sequence	11849-11880	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	CP014292	Acinetobacter baumannii strain AB34299 plasmid unnamed1, complete sequence	83116-83147	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP027121	Acinetobacter baumannii strain AR_0056 plasmid unnamed2, complete sequence	26619-26650	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP030109	Acinetobacter baumannii strain DA33382 plasmid pDA33382-85, complete sequence	39345-39376	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	CP032137	Acinetobacter haemolyticus strain sz1652 plasmid unnamed2, complete sequence	57407-57438	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP015366	Acinetobacter baumannii strain 3207 plasmid pAba3207b, complete sequence	55148-55179	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NC_010606	Acinetobacter baumannii ACICU plasmid pACICU2, complete sequence	59944-59975	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP042842	Acinetobacter baumannii strain ATCC BAA-1790 plasmid unnamed, complete sequence	20709-20740	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_KU549175	Acinetobacter baumannii strain C13 plasmid pC13-2 clone GC2, complete sequence	99256-99287	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_KX230794	Acinetobacter baumannii strain MAL plasmid pMAL-2, complete sequence	62410-62441	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP020594	Acinetobacter baumannii strain USA15 plasmid pUSA15_1, complete sequence	23687-23718	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_KR535992	Acinetobacter baumannii strain A105 plasmid pA105-1, complete sequence	65483-65514	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP026712	Acinetobacter baumannii strain AR_0063 plasmid unitig_2_pilon, complete sequence	35275-35306	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_KM977710	Acinetobacter baumannii strain D46 plasmid pD46-3, complete sequence	70301-70332	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP026706	Acinetobacter baumannii strain AR_0056 plasmid tig00000059_pilon, complete sequence	64421-64452	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_KF669606	Acinetobacter baumannii strain G7 plasmid pAb-G7-2 clone GC1 (global clone 1), complete sequence	65485-65516	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP024578	Acinetobacter baumannii strain AbPK1 plasmid pAbPK1b, complete sequence	74720-74751	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_MK243454	Acinetobacter baumannii strain 09A16CRGN0014 plasmid pCRA914-67, complete sequence	62271-62302	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_MG954377	Acinetobacter baumannii strain SGH9601 plasmid pS21-2, complete sequence	66384-66415	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP038264	Acinetobacter baumannii strain LEV1449/17Ec plasmid pEC_gr6, complete sequence	53177-53208	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP035047	Acinetobacter baumannii strain ABUH793 plasmid p74.1Kbp, complete sequence	69476-69507	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	NZ_CP033245	Acinetobacter baumannii strain 7835 plasmid pAba7835b, complete sequence	55149-55180	9	0.719
NC_008750_5	5.4\|2522786\|32\|NC_008750\|CRISPRCasFinder,CRT	2522786-2522817	32	MN693371	Marine virus AFVG_25M511, complete genome	14829-14860	9	0.719
NC_008750_5	5.4\|2522786\|32\|NC_008750\|CRISPRCasFinder,CRT	2522786-2522817	32	MN693237	Marine virus AFVG_25M495, complete genome	13484-13515	9	0.719
NC_008750_5	5.4\|2522786\|32\|NC_008750\|CRISPRCasFinder,CRT	2522786-2522817	32	MN693186	Marine virus AFVG_25M505, complete genome	14615-14646	9	0.719
NC_008750_5	5.6\|2522906\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2522906-2522937	32	NZ_CP024772	Bacillus thuringiensis LM1212 plasmid pLM1, complete sequence	102691-102722	9	0.719
NC_008750_5	5.6\|2522906\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2522906-2522937	32	NZ_CP041074	Bacillus tropicus strain LM1212-W3 plasmid p1, complete sequence	79974-80005	9	0.719
NC_008750_5	5.7\|2522966\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2522966-2522997	32	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	31164-31195	9	0.719
NC_008750_5	5.13\|2523326\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523326-2523357	32	NZ_CP020005	Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed3, complete sequence	308949-308980	9	0.719
NC_008750_5	5.18\|2523626\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523626-2523657	32	NZ_CP022727	Erwinia persicina strain B64 plasmid pEP2, complete sequence	65213-65244	9	0.719
NC_008750_5	5.18\|2523626\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523626-2523657	32	NC_014660	Acinetobacter phage Ac42, complete genome	138911-138942	9	0.719
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	NZ_CP013110	Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence	1647211-1647242	9	0.719
NC_008750_5	5.19\|2523686\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523686-2523717	32	NZ_CP013052	Sinorhizobium americanum CCGM7 plasmid A, complete sequence	345936-345967	9	0.719
NC_008750_5	5.20\|2523746\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523746-2523777	32	NC_013085	Synechococcus phage S-RSM4, complete genome	186934-186965	9	0.719
NC_008750_5	5.20\|2523746\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523746-2523777	32	FM207411	Synechococcus phage S-RSM4 complete genome	186934-186965	9	0.719
NC_008750_5	5.21\|2523806\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523806-2523837	32	MK097141	Vibrio phage P23, complete genome	6282-6313	9	0.719
NC_008750_5	5.22\|2523866\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523866-2523897	32	NZ_CP047434	Spiroplasma citri strain BLH-13 plasmid pSciBLH13-6	78588-78619	9	0.719
NC_008750_5	5.22\|2523866\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523866-2523897	32	NZ_CP013199	Spiroplasma citri strain R8-A2 plasmid pSCI15, complete sequence	14301-14332	9	0.719
NC_008750_5	5.24\|2523986\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523986-2524017	32	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	325561-325592	9	0.719
NC_008750_5	5.25\|2524046\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2524046-2524077	32	NZ_MG954377	Acinetobacter baumannii strain SGH9601 plasmid pS21-2, complete sequence	100171-100202	9	0.719
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	MN693542	Marine virus AFVG_25M165, complete genome	21302-21333	9	0.719
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	AP014366	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S41-C63, * SEQUENCING IN PROGRESS *	7518-7549	9	0.719
NC_008750_6	6.3\|3946906\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946906-3946937	32	NZ_CP046630	Streptococcus equinus strain CNU G6 plasmid p1_CNU_G6, complete sequence	68353-68384	9	0.719
NC_008750_6	6.3\|3946906\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946906-3946937	32	NZ_CP046920	Streptococcus sp. CNU G2 plasmid p_CNU_G2, complete sequence	72132-72163	9	0.719
NC_008750_6	6.3\|3946906\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946906-3946937	32	MF417886	Uncultured Caudovirales phage clone 7F_23, partial genome	644-675	9	0.719
NC_008750_6	6.11\|3947386\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947386-3947417	32	NC_013944	Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK1, complete sequence	21278-21309	9	0.719
NC_008750_6	6.11\|3947386\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947386-3947417	32	NC_013945	Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK3, complete sequence	21278-21309	9	0.719
NC_008750_6	6.15\|3947626\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947626-3947657	32	NZ_CP039694	Agrobacterium larrymoorei strain CFBP5473 plasmid pTiCFBP5473, complete sequence	291632-291663	9	0.719
NC_008750_6	6.15\|3947626\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947626-3947657	32	MN586029	Mycobacterium phage Hannaconda, complete genome	29305-29336	9	0.719
NC_008750_5	5.1\|2522606\|32\|NC_008750\|CRISPRCasFinder,CRT	2522606-2522637	32	MT325768	Psychrobacillus phage Perkons, complete genome	100707-100738	10	0.688
NC_008750_5	5.2\|2522666\|32\|NC_008750\|CRISPRCasFinder,CRT	2522666-2522697	32	MN694331	Marine virus AFVG_250M889, complete genome	37085-37116	10	0.688
NC_008750_5	5.15\|2523446\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523446-2523477	32	NZ_CP021125	Rhizobium sp. Kim5 plasmid pRetKim5a, complete sequence	6403-6434	10	0.688
NC_008750_5	5.16\|2523506\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523506-2523537	32	MH729379	Aerococcus phage vB_AviM_AVP, complete genome	26296-26327	10	0.688
NC_008750_5	5.18\|2523626\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523626-2523657	32	MN693698	Marine virus AFVG_250M751, complete genome	26292-26323	10	0.688
NC_008750_6	6.1\|3946786\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946786-3946817	32	NC_029119	Staphylococcus phage SPbeta-like, complete genome	103372-103403	10	0.688
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	MH853786	Acinetobacter phage vB_KpnM_IME285, complete genome	10289-10320	10	0.688
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	MH853787	Acinetobacter phage vB_KpnM_IME284, complete genome	8012-8043	10	0.688
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	MN096380	Mycobacterium phage Lewan, complete genome	44281-44312	10	0.688
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	NC_042028	Acinetobacter phage AB1, complete genome	23030-23061	10	0.688
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	NC_041966	Acinetobacter phage WCHABP1, complete genome	35215-35246	10	0.688
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	MH853788	Acinetobacter phage vB_KpnM_IME512, complete genome	15833-15864	10	0.688
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	KY670595	Acinetobacter phage WCHABP12, complete genome	25649-25680	10	0.688
NC_008750_6	6.2\|3946846\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3946846-3946877	32	MN166083	Acinetobacter phage Abp9, complete genome	44285-44316	10	0.688
NC_008750_6	6.8\|3947206\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947206-3947237	32	NC_029119	Staphylococcus phage SPbeta-like, complete genome	43987-44018	10	0.688
NC_008750_6	6.13\|3947506\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947506-3947537	32	NZ_CP040856	Lactobacillus johnsonii strain G2A plasmid unnamed2, complete sequence	59113-59144	10	0.688
NC_008750_6	6.13\|3947506\|32\|NC_008750\|PILER-CR,CRISPRCasFinder,CRT	3947506-3947537	32	NC_049963	Bacillus phage Juan, complete genome	8662-8693	10	0.688
NC_008750_5	5.13\|2523326\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2523326-2523357	32	NZ_CP023526	Cedecea neteri strain FDAARGOS_392 plasmid unnamed, complete sequence	247606-247637	11	0.656
NC_008750_5	5.25\|2524046\|32\|NC_008750\|CRISPRCasFinder,CRT,PILER-CR	2524046-2524077	32	NC_003276	Nostoc sp. PCC 7120 = FACHB-418 plasmid pCC7120alpha, complete sequence	131854-131885	11	0.656

1. spacer 6.15|3947626|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013115 (Shewanella xiamenensis strain T17 plasmid pSx1, complete sequence) position: , mismatch: 0, identity: 1.0

tccatgcgaagggtgacatccagcgacaacaa	CRISPR spacer
tccatgcgaagggtgacatccagcgacaacaa	Protospacer
********************************

2. spacer 6.5|3947026|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to MH648987 (Siphoviridae sp. isolate ctcj11, complete genome) position: , mismatch: 2, identity: 0.938

ataaattcaccttaaccaagttcgcgccattt	CRISPR spacer
ataaatccaccttaaccaatttcgcgccattt	Protospacer
******.************ ************

3. spacer 5.18|2523626|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to MT074146 (Bacteroides phage SJC03, complete genome) position: , mismatch: 5, identity: 0.844

aatat-tttcatattagtttccaaataaatttt	CRISPR spacer
-atatctttcatattattttctaaataaactct	Protospacer
 **** ********** ****.*******.*.*

4. spacer 5.13|2523326|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to AJ131519 (Lactobacillus bacteriophage phi adh complete genome) position: , mismatch: 6, identity: 0.812

tcgctttattcttcaattaataccatttgtga	CRISPR spacer
tcgctttattctgcgattaatacctattacga	Protospacer
************ *.*********  **..**

5. spacer 5.13|2523326|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NC_000896 (Lactobacillus prophage phiadh, complete genome) position: , mismatch: 6, identity: 0.812

tcgctttattcttcaattaataccatttgtga	CRISPR spacer
tcgctttattctgcgattaatacctattacga	Protospacer
************ *.*********  **..**

6. spacer 5.15|2523446|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to MN693861 (Marine virus AFVG_250M517, complete genome) position: , mismatch: 6, identity: 0.812

tagccgcaacagctaaaaccgcagcaccaaca	CRISPR spacer
tagcagcaacagctacaaccgcaggttctaca	Protospacer
**** ********** ********  .* ***

7. spacer 5.22|2523866|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NC_047960 (Enterobacteria phage vB_EcoS_IME347, complete genome) position: , mismatch: 6, identity: 0.812

aaccttcagcaattgccataattgcttcacct	CRISPR spacer
agcttgctgcaattgccataatttcttctcct	Protospacer
*.*.* * *************** **** ***

8. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to MN694200 (Marine virus AFVG_250M858, complete genome) position: , mismatch: 7, identity: 0.781

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
tcaaagatttaaatacttcttcttctcttgtt	Protospacer
*..**  ************ .**********

9. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to MH552526 (Siphoviridae sp. isolate ctfj46, complete genome) position: , mismatch: 7, identity: 0.781

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
ttgaattttcaaatactttaccttttatattc	Protospacer
*********.********.*****.* *  *

10. spacer 5.10|2523146|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to MT028491 (Ochrobactrum phage vB_OspM_OC, complete genome) position: , mismatch: 7, identity: 0.781

cgaatcgc---cgtttcaacgtgctttttcatgaa	CRISPR spacer
---ttcgcaagcgtttcaacatgctttttgatgat	Protospacer
    ****   *********.******** ****

11. spacer 5.18|2523626|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to MT586120 (Synechococcus phage S-CAM7 isolate 0809CC03, complete genome) position: , mismatch: 7, identity: 0.781

aatattttcatattagtttccaaataaatttt	CRISPR spacer
gattgtttcatataagtctccaaataaagtat	Protospacer
.**  ******** ***.********** * *

12. spacer 5.18|2523626|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NC_031927 (Synechococcus phage S-CAM7 isolate 0910CC49, complete genome) position: , mismatch: 7, identity: 0.781

aatattttcatattagtttccaaataaatttt	CRISPR spacer
gattgtttcatataagtctccaaataaagtat	Protospacer
.**  ******** ***.********** * *

13. spacer 5.18|2523626|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KU686213 (Synechococcus phage S-CAM7 isolate 0910SB42, complete genome) position: , mismatch: 7, identity: 0.781

aatattttcatattagtttccaaataaatttt	CRISPR spacer
gattgtttcatataagtctccaaataaagtat	Protospacer
.**  ******** ***.********** * *

14. spacer 5.18|2523626|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to JX569801 (Campylobacter phage CP30A, complete genome) position: , mismatch: 7, identity: 0.781

aatattttcatattagtttccaaataaatttt---	CRISPR spacer
attattttcatattattatccaaat---ctttagc	Protospacer
* ************* * *******   .***

15. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to FR671407 (Streptococcus phage 34117) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

16. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KY065505 (Streptococcus phage IPP69, complete genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

17. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KY065475 (Streptococcus phage IPP35, complete genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

18. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KT337367 (Streptococcus phage phiARI0826b, partial genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

19. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KT337344 (Streptococcus phage phiARI0274b, partial genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

20. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NC_031929 (Streptococcus phage phiARI0468-1, complete genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

21. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KY065474 (Streptococcus phage IPP34, complete genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

22. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KY065488 (Streptococcus phage IPP50, complete genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

23. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to FR671405 (Streptococcus phage V22) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

24. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KT337352 (Streptococcus phage phiARI0460-1, complete genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

25. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NC_024357 (Streptococcus phage K13, complete sequence) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

26. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KT337349 (Streptococcus phage phiARI0399, partial genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

27. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KY065500 (Streptococcus phage IPP64, complete genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

28. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to FR671411 (Streptococcus phage 2167) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

29. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KY065452 (Streptococcus phage IPP10, complete genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

30. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KT337356 (Streptococcus phage phiARI0468-2, complete genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

31. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to KT337340 (Streptococcus phage phiARI0031, complete genome) position: , mismatch: 7, identity: 0.781

ggtatgggtatcaatcgcccatgggtg--tgatc	CRISPR spacer
ggattgggtatcaatcgcctttgggtggttgg--	Protospacer
**  ***************. ******  **.

32. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214977 (Mycoplasma cynos strain NCTC10142 plasmid 4) position: , mismatch: 7, identity: 0.781

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ttctccatttgttgctgttgtagttgcttgtt	Protospacer
*.************.** *******..*  **

33. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214977 (Mycoplasma cynos strain NCTC10142 plasmid 4) position: , mismatch: 7, identity: 0.781

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ttctccatttgttgctgttgtagttgcttgtt	Protospacer
*.************.** *******..*  **

34. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 7, identity: 0.781

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ttctccatttgttgctgttgtagttgcttgtt	Protospacer
*.************.** *******..*  **

35. spacer 6.10|3947326|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to DQ288668 (Vibrio phage CTX strain VCE232 CtxB (ctxB) gene, partial cds; and RS2 element RstR-like protein (rstR), RstA-like protein (rstA), and RstB-like protein (rstB) genes, complete cds) position: , mismatch: 7, identity: 0.781

ttaacacgagcgtgagcggcgtcaccatagcg	CRISPR spacer
accgcgcgagcgtgagccgcatcaccatagcg	Protospacer
 . .*.*********** **.***********

36. spacer 6.10|3947326|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NC_013596 (Streptosporangium roseum DSM 43021 plasmid pSROS01, complete sequence) position: , mismatch: 7, identity: 0.781

ttaacacgagcgtgagcggcgtca-ccatagcg	CRISPR spacer
tcaacgcgagcgtgagcggcttcacccgcggc-	Protospacer
*.***.************** *** **...**

37. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP015253 (Bacillus thuringiensis Bt18247 plasmid p113275, complete sequence) position: , mismatch: 8, identity: 0.75

ttgaatttttaaatacttcaccttc----tcttgtg	CRISPR spacer
atgtattttcaaatacttcaccttttggatct----	Protospacer
 ** *****.**************.    ***

38. spacer 5.13|2523326|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NC_016748 (Marinitoga piezophila KA3 plasmid pMARPI01, complete sequence) position: , mismatch: 8, identity: 0.75

tcgctttattcttcaattaataccatttgtga	CRISPR spacer
tcgttttattcttcaaataataccttctcaag	Protospacer
***.************ ******* *.*  ..

39. spacer 5.22|2523866|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to AP014165 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C61-MedDCM-OCT-S33-C79, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.75

aaccttcag---caattgccataattgcttcacct	CRISPR spacer
---ctatggcgtcatttgccatatttgcttcacct	Protospacer
   ** ..*   ** ******** ***********

40. spacer 5.25|2524046|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to MN693424 (Marine virus AFVG_25M201, complete genome) position: , mismatch: 8, identity: 0.75

agtaagagaatttgagcttcataatgttcaat	CRISPR spacer
agttgcttgattcgtgcttcataatgttcaat	Protospacer
*** .   .***.* *****************

41. spacer 6.7|3947146|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030761 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

tgctaggtcgttggcatagtgttttggctaag	CRISPR spacer
tgctagctcgttggcatggtgttcccactctg	Protospacer
****** **********.*****.. .**  *

42. spacer 6.9|3947266|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 8, identity: 0.75

ttacttagcacgactcgccgtagttctcagcg	CRISPR spacer
cgaagtagcacgactcgccgaggttctcgccg	Protospacer
. *  *************** .******. **

43. spacer 1.2|1666371|33|NC_008750|CRISPRCasFinder matches to MT774405 (CrAssphage cr115_1, complete genome) position: , mismatch: 9, identity: 0.727

tggtcttaatggtttggatggtcttaatggagc	CRISPR spacer
ctatcttaaaggtttagatggtcttaaagaaat	Protospacer
. .****** *****.*********** *.*..

44. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP014152 (Clostridium botulinum strain BrDura plasmid pRSJ20_1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
tattatttataattacttcaccttctctatca	Protospacer
*   **** *** ***************  ..

45. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP013710 (Clostridium botulinum strain F634 plasmid pRSJ2_3, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
tattatttataattacttcaccttctctatca	Protospacer
*   **** *** ***************  ..

46. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NC_010418 (Clostridium botulinum A3 str. Loch Maree plasmid pCLK, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
tattatttataattacttcaccttctctatca	Protospacer
*   **** *** ***************  ..

47. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to MG945261 (UNVERIFIED: Microviridae sp. isolate 4002-1602, complete genome) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
gagaatttttaaaaacatcaccttctgtaaca	Protospacer
  *********** ** ********* * ...

48. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP023028 (Acinetobacter baumannii strain 10042 plasmid pAba10042b, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

49. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to MK531538 (Acinetobacter baumannii strain MC23 plasmid pMC23.1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

50. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_KY022424 (Acinetobacter baumannii strain Ab8098 plasmid pAb8098, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

51. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP035052 (Acinetobacter baumannii strain ABUH763 plasmid p74.1Kbp, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

52. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NC_025111 (Acinetobacter baumannii strain D72 plasmid pD72-2, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

53. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP016302 (Acinetobacter baumannii strain CMC-CR-MDR-Ab66 plasmid pCMCVTAb2-Ab66, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

54. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP016297 (Acinetobacter baumannii strain CMC-CR-MDR-Ab4 plasmid pCMCVTAb2-Ab4, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

55. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP033857 (Acinetobacter sp. FDAARGOS_493 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

56. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP050392 (Acinetobacter baumannii strain VB11737 plasmid pVB11737_1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

57. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP050413 (Acinetobacter baumannii strain PM192696 plasmid pPM192696_1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

58. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP050404 (Acinetobacter baumannii strain VB2486 plasmid pVB2486_1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

59. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_LT984690 (Acinetobacter baumannii isolate K50 plasmid I, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

60. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP029571 (Acinetobacter baumannii strain DA33098 plasmid pDA33098-71, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

61. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP023030 (Acinetobacter baumannii strain 9102 plasmid pAba9102a, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

62. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP023030 (Acinetobacter baumannii strain 9102 plasmid pAba9102a, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

63. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP050909 (Acinetobacter baumannii strain DT-Ab022 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

64. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP008707 (Acinetobacter baumannii strain AB5075-UW plasmid p1AB5075, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

65. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP023033 (Acinetobacter baumannii strain 7847 plasmid pAba7847b, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

66. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to CP014292 (Acinetobacter baumannii strain AB34299 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

67. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to CP014292 (Acinetobacter baumannii strain AB34299 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

68. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP027121 (Acinetobacter baumannii strain AR_0056 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

69. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP030109 (Acinetobacter baumannii strain DA33382 plasmid pDA33382-85, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

70. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to CP032137 (Acinetobacter haemolyticus strain sz1652 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

71. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP015366 (Acinetobacter baumannii strain 3207 plasmid pAba3207b, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

72. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NC_010606 (Acinetobacter baumannii ACICU plasmid pACICU2, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

73. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP042842 (Acinetobacter baumannii strain ATCC BAA-1790 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

74. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_KU549175 (Acinetobacter baumannii strain C13 plasmid pC13-2 clone GC2, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

75. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_KX230794 (Acinetobacter baumannii strain MAL plasmid pMAL-2, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

76. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP020594 (Acinetobacter baumannii strain USA15 plasmid pUSA15_1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

77. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_KR535992 (Acinetobacter baumannii strain A105 plasmid pA105-1, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

78. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP026712 (Acinetobacter baumannii strain AR_0063 plasmid unitig_2_pilon, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

79. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_KM977710 (Acinetobacter baumannii strain D46 plasmid pD46-3, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

80. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP026706 (Acinetobacter baumannii strain AR_0056 plasmid tig00000059_pilon, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

81. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_KF669606 (Acinetobacter baumannii strain G7 plasmid pAb-G7-2 clone GC1 (global clone 1), complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

82. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP024578 (Acinetobacter baumannii strain AbPK1 plasmid pAbPK1b, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

83. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_MK243454 (Acinetobacter baumannii strain 09A16CRGN0014 plasmid pCRA914-67, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

84. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_MG954377 (Acinetobacter baumannii strain SGH9601 plasmid pS21-2, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

85. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP038264 (Acinetobacter baumannii strain LEV1449/17Ec plasmid pEC_gr6, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

86. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP035047 (Acinetobacter baumannii strain ABUH793 plasmid p74.1Kbp, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

87. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to NZ_CP033245 (Acinetobacter baumannii strain 7835 plasmid pAba7835b, complete sequence) position: , mismatch: 9, identity: 0.719

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
aaaatgtcttaaatactgcaccttcttttgtc	Protospacer
  .*  *.********* ********.****

88. spacer 5.4|2522786|32|NC_008750|CRISPRCasFinder,CRT matches to MN693371 (Marine virus AFVG_25M511, complete genome) position: , mismatch: 9, identity: 0.719

--accaaagcgattgctaaaatcacggctgtaca	CRISPR spacer
gagccaga--gattgctaaaatcatggctgctgt	Protospacer
  .***.*  **************.*****.

89. spacer 5.4|2522786|32|NC_008750|CRISPRCasFinder,CRT matches to MN693237 (Marine virus AFVG_25M495, complete genome) position: , mismatch: 9, identity: 0.719

--accaaagcgattgctaaaatcacggctgtaca	CRISPR spacer
gagccaga--gattgctaaaatcatggctgctgt	Protospacer
  .***.*  **************.*****.

90. spacer 5.4|2522786|32|NC_008750|CRISPRCasFinder,CRT matches to MN693186 (Marine virus AFVG_25M505, complete genome) position: , mismatch: 9, identity: 0.719

--accaaagcgattgctaaaatcacggctgtaca	CRISPR spacer
gagccaga--gattgctaaaatcatggctgctgt	Protospacer
  .***.*  **************.*****.

91. spacer 5.6|2522906|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024772 (Bacillus thuringiensis LM1212 plasmid pLM1, complete sequence) position: , mismatch: 9, identity: 0.719

tagcgattgcagatacctatcttgttcagtta	CRISPR spacer
aataatttacagatacctatctttttcaggtg	Protospacer
 *  . **.************** ***** *.

92. spacer 5.6|2522906|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP041074 (Bacillus tropicus strain LM1212-W3 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.719

tagcgattgcagatacctatcttgttcagtta	CRISPR spacer
aataatttacagatacctatctttttcaggtg	Protospacer
 *  . **.************** ***** *.

93. spacer 5.7|2522966|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 9, identity: 0.719

tcgtattcgaccagttcgagtttccgaccaat	CRISPR spacer
ttcgccccgaccagctcgtgtttccgaccaag	Protospacer
*.   ..*******.*** ************

94. spacer 5.13|2523326|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020005 (Bacillus thuringiensis strain Bacillus thuringiensis L-7601 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.719

tcgctttattcttcaattaataccatttgtga	CRISPR spacer
gttttttattcttcaattcacaccatttttct	Protospacer
 . .************** *.******* *

95. spacer 5.18|2523626|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022727 (Erwinia persicina strain B64 plasmid pEP2, complete sequence) position: , mismatch: 9, identity: 0.719

aatattttcatattagtttccaaataaatttt	CRISPR spacer
gtaattttcatattggtatccaaataagggtg	Protospacer
.  ***********.** *********.  *

96. spacer 5.18|2523626|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NC_014660 (Acinetobacter phage Ac42, complete genome) position: , mismatch: 9, identity: 0.719

aatattttcatattagtttccaaataaatttt	CRISPR spacer
atagttttcatgttaatttccaaataataagt	Protospacer
*  .*******.***.***********    *

97. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013110 (Sinorhizobium americanum strain CFNEI 73 plasmid C, complete sequence) position: , mismatch: 9, identity: 0.719

ggtatgggtatcaatcgcccatgggtgtgatc	CRISPR spacer
gatatggggatcaatcgcacatgggagcagat	Protospacer
*.****** ********* ****** *... .

98. spacer 5.19|2523686|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013052 (Sinorhizobium americanum CCGM7 plasmid A, complete sequence) position: , mismatch: 9, identity: 0.719

ggtatgggtatcaatcgcccatgggtgtgatc	CRISPR spacer
gatatggggatcaatcgcacatgggagcagat	Protospacer
*.****** ********* ****** *... .

99. spacer 5.20|2523746|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NC_013085 (Synechococcus phage S-RSM4, complete genome) position: , mismatch: 9, identity: 0.719

attgtgattatgcccgtctagcttatacagac	CRISPR spacer
gcggaaattatgcccgtctaccctatacaatc	Protospacer
.. * .************** *.******. *

100. spacer 5.20|2523746|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to FM207411 (Synechococcus phage S-RSM4 complete genome) position: , mismatch: 9, identity: 0.719

attgtgattatgcccgtctagcttatacagac	CRISPR spacer
gcggaaattatgcccgtctaccctatacaatc	Protospacer
.. * .************** *.******. *

101. spacer 5.21|2523806|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to MK097141 (Vibrio phage P23, complete genome) position: , mismatch: 9, identity: 0.719

caaacggtaacgctaaaccctgttgccaaatc	CRISPR spacer
tttacggtaacattaaaccctgttgcctacgt	Protospacer
.  ********..************** *  .

102. spacer 5.22|2523866|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047434 (Spiroplasma citri strain BLH-13 plasmid pSciBLH13-6) position: , mismatch: 9, identity: 0.719

aaccttcagcaattgccataattgcttcacct	CRISPR spacer
ttgcaacagcaattgccatacttacttcacta	Protospacer
   *  ************** **.******.

103. spacer 5.22|2523866|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013199 (Spiroplasma citri strain R8-A2 plasmid pSCI15, complete sequence) position: , mismatch: 9, identity: 0.719

aaccttcagcaattgccataattgcttcacct	CRISPR spacer
ttgcaacagcaattgccatacttacttcacta	Protospacer
   *  ************** **.******.

104. spacer 5.24|2523986|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 9, identity: 0.719

acaaaagcggtcgctgcaatggtggccgtggt	CRISPR spacer
gacgaagcggtcgatgcagtggtggccggcgg	Protospacer
.  .********* ****.*********  *

105. spacer 5.25|2524046|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MG954377 (Acinetobacter baumannii strain SGH9601 plasmid pS21-2, complete sequence) position: , mismatch: 9, identity: 0.719

agtaagagaatttgagcttcataatgttcaat	CRISPR spacer
taaaggagaatttgagcttcttaatattcttc	Protospacer
 . *.*************** ****.***  .

106. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to MN693542 (Marine virus AFVG_25M165, complete genome) position: , mismatch: 9, identity: 0.719

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
atctgcatttattgttgatgtagttgtgtttg	Protospacer
 .** *****.**************.*  .*

107. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to AP014366 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S41-C63, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
tcacgacatttttgttgatgtacttattactg	Protospacer
** .    ** *********** ********

108. spacer 6.3|3946906|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046630 (Streptococcus equinus strain CNU G6 plasmid p1_CNU_G6, complete sequence) position: , mismatch: 9, identity: 0.719

tgtgtcagtaaaagtatcaggcattaattcag	CRISPR spacer
ggatagagtagaagtatcacgcattaattctc	Protospacer
 *    ****.******** **********

109. spacer 6.3|3946906|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046920 (Streptococcus sp. CNU G2 plasmid p_CNU_G2, complete sequence) position: , mismatch: 9, identity: 0.719

tgtgtcagtaaaagtatcaggcattaattcag	CRISPR spacer
ggatagagtagaagtatcacgcattaattctc	Protospacer
 *    ****.******** **********

110. spacer 6.3|3946906|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to MF417886 (Uncultured Caudovirales phage clone 7F_23, partial genome) position: , mismatch: 9, identity: 0.719

tgtgtcagtaaaagtatcaggcattaattcag	CRISPR spacer
tacagcttgaacagtatcagggattaattcag	Protospacer
*... *   ** ********* **********

111. spacer 6.11|3947386|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NC_013944 (Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK1, complete sequence) position: , mismatch: 9, identity: 0.719

tttaccgtttctttggctgctgcaatcttctt	CRISPR spacer
tgaattgtttctttgcctgctgcaatattgcc	Protospacer
*  *..********* ********** ** ..

112. spacer 6.11|3947386|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NC_013945 (Staphylococcus simulans bv. staphylolyticus strain NRRL B-2628 plasmid pACK3, complete sequence) position: , mismatch: 9, identity: 0.719

tttaccgtttctttggctgctgcaatcttctt	CRISPR spacer
tgaattgtttctttgcctgctgcaatattgcc	Protospacer
*  *..********* ********** ** ..

113. spacer 6.15|3947626|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039694 (Agrobacterium larrymoorei strain CFBP5473 plasmid pTiCFBP5473, complete sequence) position: , mismatch: 9, identity: 0.719

tccatgcgaagggtgacatccagcgacaacaa	CRISPR spacer
agcattcgatgggtgacatccagcggaaggag	Protospacer
  *** *** ***************. *. *.

114. spacer 6.15|3947626|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to MN586029 (Mycobacterium phage Hannaconda, complete genome) position: , mismatch: 9, identity: 0.719

tccatgcgaagggtgacatccagcgacaacaa	CRISPR spacer
aactggtccagggtgccttccagcgacaacaa	Protospacer
  *  *.  ****** * **************

115. spacer 5.1|2522606|32|NC_008750|CRISPRCasFinder,CRT matches to MT325768 (Psychrobacillus phage Perkons, complete genome) position: , mismatch: 10, identity: 0.688

ttgaatttttaaatacttcaccttctcttgtg	CRISPR spacer
tataattattaaatacttcacctactacaacc	Protospacer
*  **** *************** ** . ..

116. spacer 5.2|2522666|32|NC_008750|CRISPRCasFinder,CRT matches to MN694331 (Marine virus AFVG_250M889, complete genome) position: , mismatch: 10, identity: 0.688

gtgttaggtggtaaaacgctactcatagagtc	CRISPR spacer
aatcctgatgggaaaacgctactcgtagagta	Protospacer
.  .. *.*** ************.******

117. spacer 5.15|2523446|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021125 (Rhizobium sp. Kim5 plasmid pRetKim5a, complete sequence) position: , mismatch: 10, identity: 0.688

tagccgcaacagctaaaaccgcagcaccaaca	CRISPR spacer
tagccgcaacagctaatatcgcacaatttgtg	Protospacer
**************** *.****  *.. ...

118. spacer 5.16|2523506|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to MH729379 (Aerococcus phage vB_AviM_AVP, complete genome) position: , mismatch: 10, identity: 0.688

agatatgagaacagctttaggtcaaacagcta	CRISPR spacer
ttttatgagaacagatttaggtaaaaagattg	Protospacer
   *********** ******* *** ...*.

119. spacer 5.18|2523626|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to MN693698 (Marine virus AFVG_250M751, complete genome) position: , mismatch: 10, identity: 0.688

aatattttcatattagtttccaaataaatttt	CRISPR spacer
tttattttcatattagcttcccaatctgccat	Protospacer
  **************.**** ***  ... *

120. spacer 6.1|3946786|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NC_029119 (Staphylococcus phage SPbeta-like, complete genome) position: , mismatch: 10, identity: 0.688

cgcgccaaagttgtaaattaggcttaggtacg	CRISPR spacer
tagatgaaagttttaaattagtcttaggtaac	Protospacer
.. .. ****** ******** ********

121. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to MH853786 (Acinetobacter phage vB_KpnM_IME285, complete genome) position: , mismatch: 10, identity: 0.688

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ttgctcatttgttgttgatctggttatttacg	Protospacer
*. ..************** *.******  .

122. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to MH853787 (Acinetobacter phage vB_KpnM_IME284, complete genome) position: , mismatch: 10, identity: 0.688

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ttgctcatttgttgttgatctggttatttacg	Protospacer
*. ..************** *.******  .

123. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to MN096380 (Mycobacterium phage Lewan, complete genome) position: , mismatch: 10, identity: 0.688

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ctccccatttgttgttgatctggttatgcagc	Protospacer
..*.*************** *.*****    .

124. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NC_042028 (Acinetobacter phage AB1, complete genome) position: , mismatch: 10, identity: 0.688

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ttgctcatttgttgttgatctggttatttacg	Protospacer
*. ..************** *.******  .

125. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NC_041966 (Acinetobacter phage WCHABP1, complete genome) position: , mismatch: 10, identity: 0.688

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ttactcatttgttgttgatctggttatttacg	Protospacer
*. ..************** *.******  .

126. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to MH853788 (Acinetobacter phage vB_KpnM_IME512, complete genome) position: , mismatch: 10, identity: 0.688

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ttactcatttgttgttgatctggttatttacg	Protospacer
*. ..************** *.******  .

127. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to KY670595 (Acinetobacter phage WCHABP12, complete genome) position: , mismatch: 10, identity: 0.688

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ttactcatttgttgttgatctggttatttacg	Protospacer
*. ..************** *.******  .

128. spacer 6.2|3946846|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to MN166083 (Acinetobacter phage Abp9, complete genome) position: , mismatch: 10, identity: 0.688

tcctccatttgttgttgatgtagttattactt	CRISPR spacer
ttactcatttgttgttgatctggttatttacg	Protospacer
*. ..************** *.******  .

129. spacer 6.8|3947206|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NC_029119 (Staphylococcus phage SPbeta-like, complete genome) position: , mismatch: 10, identity: 0.688

attaaattcattagcagtaacataaacctcga	CRISPR spacer
tacaaattcattagcagttacattaattgcag	Protospacer
  .*************** **** **.. *..

130. spacer 6.13|3947506|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040856 (Lactobacillus johnsonii strain G2A plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

acggagtttaaatctgcatacttagatttaaa	CRISPR spacer
gaagcagttaaatcagcatacttagacttagc	Protospacer
. .* . ******* ***********.***.

131. spacer 6.13|3947506|32|NC_008750|PILER-CR,CRISPRCasFinder,CRT matches to NC_049963 (Bacillus phage Juan, complete genome) position: , mismatch: 10, identity: 0.688

acggagtttaaatctgcatacttagatttaaa	CRISPR spacer
gtatatcttaaatctgcatacttagttgtacg	Protospacer
... * .****************** * ** .

132. spacer 5.13|2523326|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023526 (Cedecea neteri strain FDAARGOS_392 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.656

tcgctttattcttcaattaataccatttgtga	CRISPR spacer
ctcgattattctgaaattaataccatttaaat	Protospacer
..   *******  **************. .

133. spacer 5.25|2524046|32|NC_008750|CRISPRCasFinder,CRT,PILER-CR matches to NC_003276 (Nostoc sp. PCC 7120 = FACHB-418 plasmid pCC7120alpha, complete sequence) position: , mismatch: 11, identity: 0.656

agtaagagaatttgagcttcataatgttcaat	CRISPR spacer
gcactaagaatttgagctttataatcttcttc	Protospacer
.    .*************.***** ***  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

124196 : 132734

Bacillus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011787520.1\|124196_125561_-	GHKL domain-containing protein	W8CYF6	Bacillus_phage	4.0e-10	25.4
WP_011787521.1\|125553_126249_-	response regulator transcription factor	Q6XM27	Feldmannia_irregularis_virus	1.1e-06	26.5
WP_011787522.1\|126251_126554_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_011787523.1\|126958_127903_+	hypothetical protein	NA	NA	NA	NA
WP_011787524.1\|127984_128458_+	peroxiredoxin	M1I839	Pelagibacter_phage	5.5e-23	47.4
WP_011787525.1\|128538_130521_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	2.8e-12	28.6
WP_011787526.1\|130649_131966_-	two-component system sensor histidine kinase EnvZ	W8CYF6	Bacillus_phage	1.1e-12	24.4
WP_011787527.1\|132008_132734_-	two-component system response regulator OmpR	W8CYM9	Bacillus_phage	1.3e-31	34.7

DBSCAN-SWA_2

456335 : 484116

Lysinibacillus_phage(40.0%)

transposase,integrase

attL 454312:454371|attR 477430:480802

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
454312:454371	attL	NA	NA	NA	NA
WP_011918377.1\|456335_457625_+\|transposase	ISL3-like element ISPpu12 family transposase	A0A2D1GQC1	Lysinibacillus_phage	1.6e-85	40.4
WP_011787809.1\|457897_459010_-	iron-containing alcohol dehydrogenase	NA	NA	NA	NA
WP_011787810.1\|459025_460420_-	aldehyde dehydrogenase EutE	NA	NA	NA	NA
WP_011787811.1\|460416_460926_-	hypothetical protein	NA	NA	NA	NA
WP_011787812.1\|460958_461237_-	EutN/CcmL family microcompartment protein	NA	NA	NA	NA
WP_011918379.1\|461241_461721_-	microcompartment protein PduM	NA	NA	NA	NA
WP_011787814.1\|461734_462370_-	phosphate propanoyltransferase	NA	NA	NA	NA
WP_011787815.1\|462374_463241_-	BMC domain-containing protein	NA	NA	NA	NA
WP_011787816.1\|463268_463559_-	BMC domain-containing protein	NA	NA	NA	NA
WP_011787817.1\|463630_464458_-	aquaporin	M1HWZ0	Paramecium_bursaria_Chlorella_virus	4.5e-12	26.7
WP_011787818.1\|464492_465413_-	glycyl-radical enzyme activating protein	NA	NA	NA	NA
WP_011787819.1\|465551_468095_-	glycyl radical protein	A0A2K8HKE5	Bacteriophage	6.0e-07	50.9
WP_011787820.1\|468119_468935_-	propanediol utilization microcompartment protein PduB	NA	NA	NA	NA
WP_011787821.1\|468931_469234_-	propanediol utilization microcompartment protein PduA	NA	NA	NA	NA
WP_011787822.1\|470246_471107_-	PTS mannose transporter subunit IID	NA	NA	NA	NA
WP_011787823.1\|471117_471915_-	PTS mannose/fructose/sorbose transporter subunit IIC	NA	NA	NA	NA
WP_011787824.1\|471930_472245_-	PTS transporter subunit IIB	NA	NA	NA	NA
WP_077910088.1\|472310_473279_-\|transposase	IS5 family transposase	A0A1B0VFY5	Salmonella_phage	4.1e-182	97.8
WP_011787827.1\|473983_474586_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_011787828.1\|474828_475860_+\|transposase	IS630-like element ISSpu2 family transposase	NA	NA	NA	NA
WP_011787829.1\|476386_477268_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004364961.1\|477516_477924_-	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_011787806.1\|478019_478916_+	cation transporter	NA	NA	NA	NA
WP_011787807.1\|478919_479432_+	signal peptidase II	NA	NA	NA	NA
WP_011918377.1\|479453_480743_+\|transposase	ISL3-like element ISPpu12 family transposase	A0A2D1GQC1	Lysinibacillus_phage	1.6e-85	40.4
WP_011787830.1\|481035_484116_+\|transposase	Tn3 family transposase	NA	NA	NA	NA
477430:480802	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1207193 : 1278506

Liberibacter_phage(12.5%)

tRNA,integrase,transposase,protease

attL 1204437:1204453|attR 1268535:1268551

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1204437:1204453	attL	NA	NA	NA	NA
WP_083758257.1\|1207193_1209152_+\|protease	ATP-dependent zinc metalloprotease FtsH	A0A0P0BXI2	Ostreococcus_lucimarinus_virus	2.8e-121	44.4
WP_011788438.1\|1209363_1210197_+	dihydropteroate synthase	S4W084	Pandoravirus	9.7e-15	29.1
WP_011788439.1\|1210277_1211615_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_006082720.1\|1211809_1212592_+	triose-phosphate isomerase	NA	NA	NA	NA
WP_011788440.1\|1212593_1212929_+	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_011788441.1\|1213360_1213816_+	ribosome maturation factor RimP	NA	NA	NA	NA
WP_011788442.1\|1213845_1215345_+	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_011788443.1\|1215370_1218013_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.1e-24	23.9
WP_011788444.1\|1218076_1218526_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_011788445.1\|1218525_1219482_+\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_011788446.1\|1219610_1219880_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_011788447.1\|1219956_1222005_-	EAL domain-containing protein	NA	NA	NA	NA
WP_011788448.1\|1222200_1224300_+	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_011788449.1\|1224491_1225397_+	lipoprotein NlpI	NA	NA	NA	NA
WP_000127614.1\|1226020_1226215_+	DNA-binding protein	NA	NA	NA	NA
WP_008305558.1\|1226231_1227473_-\|integrase	integrase family protein	A0A291AWU1	Escherichia_phage	3.0e-73	38.8
WP_011788450.1\|1227474_1227744_-	hypothetical protein	NA	NA	NA	NA
WP_011788451.1\|1227746_1228721_-	ParM/StbA family protein	NA	NA	NA	NA
WP_011788453.1\|1229185_1229629_+	hypothetical protein	NA	NA	NA	NA
WP_011788454.1\|1229639_1230908_-	translesion error-prone DNA polymerase V subunit UmuC	I6RSM4	Salmonella_phage	5.0e-140	59.5
WP_011788455.1\|1230915_1231365_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A218MND2	uncultured_virus	4.1e-36	57.1
WP_011788456.1\|1232004_1232910_+	DNA polymerase III subunit epsilon	A0A2H4P6W5	Pseudomonas_phage	8.1e-07	25.6
WP_011788457.1\|1232997_1233297_+	hypothetical protein	NA	NA	NA	NA
WP_011788458.1\|1233618_1234542_+	WYL domain-containing protein	NA	NA	NA	NA
WP_011788459.1\|1234655_1237079_+	SAM-dependent DNA methyltransferase	A0A220A2U4	Liberibacter_phage	4.6e-25	28.4
WP_011788460.1\|1237085_1238375_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_011788461.1\|1238384_1239548_+	DUF4268 domain-containing protein	NA	NA	NA	NA
WP_011788462.1\|1239562_1242580_+	type I restriction endonuclease subunit R	A0A220A398	Liberibacter_phage	1.7e-21	24.6
WP_011788463.1\|1242602_1243688_+	ATP-binding protein	NA	NA	NA	NA
WP_000811851.1\|1243710_1244262_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_011788464.1\|1244565_1244934_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_011788465.1\|1244943_1246098_+	SAVED domain-containing protein	NA	NA	NA	NA
WP_011788466.1\|1246090_1247281_+	nucleotidyltransferase	NA	NA	NA	NA
WP_011788467.1\|1247281_1247995_+	hypothetical protein	NA	NA	NA	NA
WP_011788468.1\|1248112_1250263_+	phosphohydrolase	NA	NA	NA	NA
WP_011788469.1\|1250311_1252135_+	conjugative transfer system coupling protein TraD	NA	NA	NA	NA
WP_011788470.1\|1252144_1252705_+	hypothetical protein	NA	NA	NA	NA
WP_011788471.1\|1252691_1253327_+	DUF4400 domain-containing protein	NA	NA	NA	NA
WP_011788472.1\|1253353_1253941_-	hypothetical protein	NA	NA	NA	NA
WP_011788473.1\|1253954_1254194_-	hypothetical protein	NA	NA	NA	NA
WP_011788474.1\|1254229_1254511_+	type IV conjugative transfer system protein TraL	NA	NA	NA	NA
WP_000667170.1\|1254507_1255134_+	hypothetical protein	NA	NA	NA	NA
WP_020743644.1\|1255117_1256014_+	hypothetical protein	NA	NA	NA	NA
WP_011788476.1\|1256016_1257306_+	conjugal transfer protein TraB	NA	NA	NA	NA
WP_015066557.1\|1257380_1257953_+	TraV family lipoprotein	NA	NA	NA	NA
WP_011788478.1\|1257949_1258339_+	hypothetical protein	NA	NA	NA	NA
WP_011788479.1\|1258747_1261243_+	copper-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	4.5e-92	32.4
WP_011788480.1\|1261268_1261733_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_011788481.1\|1262839_1263595_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	5.6e-70	55.4
WP_011788482.1\|1263606_1265148_-\|transposase	IS21-like element ISSpu5 family transposase	K4I413	Acidithiobacillus_phage	3.5e-143	50.5
WP_011788484.1\|1265547_1267053_+\|transposase	IS21-like element ISSpu15 family transposase	NA	NA	NA	NA
WP_011788485.1\|1267045_1267801_+	DUF815 domain-containing protein	NA	NA	NA	NA
WP_086022277.1\|1267823_1268974_-\|transposase	IS3-like element ISShes1 family transposase	A0A0P0I4A4	Acinetobacter_phage	4.0e-51	39.8
1268535:1268551	attR	NA	NA	NA	NA
WP_011788488.1\|1269594_1270020_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_011788489.1\|1270782_1271136_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011788490.1\|1272500_1273529_+	cation transporter	A0A1V0SED0	Indivirus	1.3e-16	25.9
WP_011788491.1\|1273573_1273852_+	transcriptional regulator	NA	NA	NA	NA
WP_011788492.1\|1274448_1277103_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.3e-125	39.0
WP_086022277.1\|1277355_1278506_-\|transposase	IS3-like element ISShes1 family transposase	A0A0P0I4A4	Acinetobacter_phage	4.0e-51	39.8

DBSCAN-SWA_4

1393027 : 1400495

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011788582.1\|1393027_1394695_-	energy-dependent translational throttle protein EttA	A0A1V0SKJ1	Klosneuvirus	2.5e-38	27.9
WP_011788583.1\|1394884_1396138_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	9.2e-102	53.6
WP_011788584.1\|1396338_1396788_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_083758292.1\|1396907_1398050_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	2.3e-51	35.5
WP_011788586.1\|1398061_1398718_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	7.8e-28	34.5
WP_011788587.1\|1398783_1399887_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	9.0e-69	40.0
WP_007646164.1\|1400018_1400495_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.1e-30	47.0

DBSCAN-SWA_5

1428391 : 1443480

uncultured_Mediterranean_phage(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011788605.1\|1428391_1429687_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	3.0e-132	58.9
WP_011788606.1\|1429786_1430086_+	cell division protein FtsB	NA	NA	NA	NA
WP_011788607.1\|1430094_1430856_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_011788608.1\|1430896_1431382_+	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_011788609.1\|1431403_1432486_+\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_011788610.1\|1432482_1433232_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.0e-71	52.7
WP_011788611.1\|1433228_1433864_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	4.1e-34	50.0
WP_011788612.1\|1433956_1434841_+	peptidoglycan DD-metalloendopeptidase family protein	I3PV79	Clostridium_phage	6.9e-11	31.9
WP_011788613.1\|1434922_1435903_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	6.4e-34	32.9
WP_011788614.1\|1435999_1438570_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	1.2e-31	23.0
WP_011788615.1\|1438953_1440027_+	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	1.1e-111	62.2
WP_011788616.1\|1440101_1440515_+	regulatory protein RecX	NA	NA	NA	NA
WP_041408349.1\|1440855_1443480_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	3.5e-79	38.9

DBSCAN-SWA_6

2145750 : 2155867

Faustovirus(12.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011789189.1\|2145750_2146965_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	2.3e-33	31.4
WP_011789190.1\|2147003_2147387_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	2.2e-51	76.6
WP_011789191.1\|2147401_2147725_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	8.3e-23	46.3
WP_011789192.1\|2147741_2148266_+	co-chaperone HscB	NA	NA	NA	NA
WP_011789193.1\|2148334_2150197_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	2.3e-104	38.8
WP_011789194.1\|2150205_2150544_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_011789195.1\|2150702_2151608_+	30S ribosomal protein S6--L-glutamate ligase	I3ULC9	Synechococcus_phage	9.4e-40	33.6
WP_011789196.1\|2151678_2151876_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_014610490.1\|2152106_2152274_+	hypothetical protein	NA	NA	NA	NA
WP_011789197.1\|2152471_2152903_+	nucleoside-diphosphate kinase	K7YW26	Megavirus	1.1e-17	40.2
WP_011789198.1\|2153140_2153584_+	Hsp20 family protein	A0A2L0V0Y9	Agrobacterium_phage	2.4e-20	49.5
WP_011789199.1\|2153654_2154149_-	acetolactate synthase small subunit	NA	NA	NA	NA
WP_011789200.1\|2154148_2155867_-	acetolactate synthase 3 large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	6.8e-55	29.5

DBSCAN-SWA_7

2317086 : 2328349

uncultured_Caudovirales_phage(42.86%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011789323.1\|2317086_2319777_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	8.3e-84	48.5
WP_011789324.1\|2319853_2320480_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_011789325.1\|2320488_2321820_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	4.4e-78	39.4
WP_011789326.1\|2321812_2322187_+	fluoride efflux transporter CrcB	A0A2H4J148	uncultured_Caudovirales_phage	6.3e-06	37.0
WP_011789327.1\|2322205_2323492_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.6e-99	45.5
WP_011789328.1\|2323509_2323632_+	hypothetical protein	NA	NA	NA	NA
WP_011789329.1\|2323724_2324063_-	TusE/DsrC/DsvC family sulfur relay protein	NA	NA	NA	NA
WP_011789330.1\|2324056_2324338_-	sulfurtransferase complex subunit TusB	NA	NA	NA	NA
WP_011789331.1\|2324337_2324694_-	sulfurtransferase complex subunit TusC	NA	NA	NA	NA
WP_081429791.1\|2324708_2325101_-	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	8.0e-20	41.7
WP_011789333.1\|2325158_2325818_-	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	2.1e-33	43.4
WP_041408179.1\|2326056_2326959_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011789335.1\|2327074_2328349_+	Bcr/CflA family multidrug efflux MFS transporter	S4TR35	Salmonella_phage	1.3e-13	23.5

DBSCAN-SWA_8

2839300 : 2887328

Vibrio_phage(45.0%)

integrase,head,tail,capsid,protease,portal

attL 2831252:2831270|attR 2887536:2887554

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2831252:2831270	attL	NA	NA	NA	NA
WP_011789741.1\|2839300_2839951_-\|tail	tail assembly protein	A0A1V0E8A0	Vibrio_phage	1.0e-64	68.6
WP_083758299.1\|2840071_2840878_-	Rha family transcriptional regulator	Q38450	Enterobacteria_phage	7.4e-28	41.0
WP_011789743.1\|2840958_2841633_-	DNA-binding protein	A0A2H4J506	uncultured_Caudovirales_phage	7.5e-58	58.1
WP_083758265.1\|2841629_2841800_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_011789744.1\|2841910_2842402_+	Arc family DNA-binding protein	A0A0U4B0M9	Pseudomonas_phage	9.1e-05	39.1
WP_011789745.1\|2842440_2842959_-	hypothetical protein	NA	NA	NA	NA
WP_011789746.1\|2843045_2843759_-	C40 family peptidase	A0A1V1FD38	Vibrio_phage	4.3e-72	54.4
WP_011789747.1\|2843810_2844536_-\|tail	phage minor tail protein L	A0A1V0E876	Vibrio_phage	4.4e-96	64.5
WP_041408202.1\|2844528_2844810_-	hypothetical protein	Q8H9M8	Vibrio_phage	4.2e-23	56.7
WP_011789749.1\|2844802_2846077_-	RNA-directed DNA polymerase	D4HTV9	Vibrio_phage	2.5e-179	72.3
WP_011789750.1\|2846073_2846427_-	diversity-generating retroelement protein Avd	D4HTV8	Vibrio_phage	2.8e-40	78.2
WP_157037407.1\|2846486_2847428_-	SUMF1/EgtB/PvdO family nonheme iron enzyme	Q8H9N0	Vibrio_phage	1.4e-110	63.0
WP_011789752.1\|2847731_2848067_-\|tail	phage tail protein	A0A1V1FDP8	Vibrio_phage	1.7e-31	58.9
WP_011789753.1\|2848070_2848376_-	hypothetical protein	NA	NA	NA	NA
WP_011789754.1\|2848377_2851794_-\|tail	phage tail tape measure protein	A0A1V0E821	Vibrio_phage	1.1e-205	50.2
WP_011789755.1\|2851874_2852018_-	hypothetical protein	NA	NA	NA	NA
WP_011789756.1\|2852056_2852551_-	hypothetical protein	A0A1V0E823	Vibrio_phage	5.9e-28	46.2
WP_011789757.1\|2852640_2853114_-\|tail	tail protein	A0A1V0E8B3	Vibrio_phage	4.7e-51	64.7
WP_011789758.1\|2853204_2853573_-	DUF3168 domain-containing protein	A0A1V0E8A7	Vibrio_phage	4.8e-35	58.2
WP_011789759.1\|2853569_2854034_-	HK97 gp10 family phage protein	A0A1V0E895	Vibrio_phage	6.9e-47	59.7
WP_011789760.1\|2854035_2854398_-\|head,tail	head-tail adaptor protein	Q9XJT0	Pseudomonas_phage	5.8e-33	56.3
WP_011789761.1\|2854397_2854694_-\|head,tail	phage gp6-like head-tail connector protein	Q9XJT1	Pseudomonas_phage	8.1e-25	59.4
WP_011789762.1\|2854715_2855015_-	hypothetical protein	NA	NA	NA	NA
WP_011789763.1\|2855111_2856302_-\|capsid	phage major capsid protein	Q9XJT3	Pseudomonas_phage	3.5e-143	68.5
WP_011789764.1\|2856314_2857169_-\|protease	Clp protease ClpP	A0A1V0E8B8	Vibrio_phage	1.9e-82	58.6
WP_011789765.1\|2857178_2858477_-\|portal	phage portal protein	A0A0U4IIV7	Pseudomonas_phage	3.3e-139	63.0
WP_011789766.1\|2858473_2858635_-	hypothetical protein	NA	NA	NA	NA
WP_011789769.1\|2860859_2861189_-	HNH endonuclease	B5WZZ4	Pseudomonas_phage	7.1e-30	55.2
WP_011789770.1\|2861185_2861575_-	hypothetical protein	NA	NA	NA	NA
WP_011789771.1\|2861567_2861837_-	hypothetical protein	A0A1B1ITN8	uncultured_Mediterranean_phage	4.8e-08	45.5
WP_011789772.1\|2861953_2862478_-	hypothetical protein	NA	NA	NA	NA
WP_011789773.1\|2862727_2863240_-	lysozyme	A0A0U1UNS2	Pseudomonas_phage	1.5e-34	48.0
WP_041408205.1\|2863242_2863434_-	hypothetical protein	NA	NA	NA	NA
WP_011789775.1\|2863598_2864189_-	hypothetical protein	NA	NA	NA	NA
WP_011789776.1\|2864247_2864571_-	DUF4406 domain-containing protein	A0A2I6TCY5	Escherichia_phage	3.9e-20	53.5
WP_041408206.1\|2864570_2864822_-	hypothetical protein	NA	NA	NA	NA
WP_041408207.1\|2864814_2864997_-	hypothetical protein	NA	NA	NA	NA
WP_011789777.1\|2865004_2865328_-	hypothetical protein	Q6V7R0	Burkholderia_virus	7.8e-13	46.2
WP_041408208.1\|2865327_2865528_-	hypothetical protein	NA	NA	NA	NA
WP_041408209.1\|2865520_2865742_-	hypothetical protein	NA	NA	NA	NA
WP_011789779.1\|2865849_2867049_-\|integrase	tyrosine-type recombinase/integrase	A0A067ZJC5	Vibrio_phage	3.5e-66	37.7
WP_011789780.1\|2867048_2867648_-	hypothetical protein	NA	NA	NA	NA
WP_011789781.1\|2867647_2868217_-	hypothetical protein	NA	NA	NA	NA
WP_011789782.1\|2868213_2868645_-	hypothetical protein	NA	NA	NA	NA
WP_011789783.1\|2868644_2869151_-	hypothetical protein	I6S2X8	Marinomonas_phage	2.1e-25	41.8
WP_011789784.1\|2869147_2869540_-	hypothetical protein	NA	NA	NA	NA
WP_157037408.1\|2869523_2870111_-	hypothetical protein	A0A2D1GNB3	Pseudomonas_phage	1.2e-06	28.6
WP_011789786.1\|2870055_2871123_-	replication protein	A0A1I9KG10	Aeromonas_phage	3.6e-54	45.9
WP_011789787.1\|2871179_2871437_-	hypothetical protein	NA	NA	NA	NA
WP_011789788.1\|2871436_2871631_-	hypothetical protein	NA	NA	NA	NA
WP_011789789.1\|2871623_2872205_-	hypothetical protein	NA	NA	NA	NA
WP_011789790.1\|2872238_2872538_-	helix-turn-helix transcriptional regulator	A0A1V0E8C7	Vibrio_phage	1.7e-09	46.3
WP_041408210.1\|2872580_2873246_+	LexA family transcriptional regulator	Q37946	Enterobacteria_phage	8.7e-67	59.0
WP_011789792.1\|2873280_2873703_+	hypothetical protein	NA	NA	NA	NA
WP_011789793.1\|2873715_2874612_+	DNA polymerase III subunit epsilon	X2KQX9	Campylobacter_phage	1.2e-18	28.8
WP_041408211.1\|2874671_2875307_-\|tail	tail assembly protein	A0A1V0E8A0	Vibrio_phage	5.6e-63	67.4
WP_041408212.1\|2875843_2876056_+	hypothetical protein	NA	NA	NA	NA
WP_041408213.1\|2876396_2876612_+	hypothetical protein	NA	NA	NA	NA
WP_011789795.1\|2876608_2876848_+	hypothetical protein	NA	NA	NA	NA
WP_011072900.1\|2876850_2876928_+	phage protein	NA	NA	NA	NA
WP_011789796.1\|2876988_2877414_+	hypothetical protein	NA	NA	NA	NA
WP_011789797.1\|2877406_2877685_+	hypothetical protein	NA	NA	NA	NA
WP_011789799.1\|2878173_2878698_+	hypothetical protein	NA	NA	NA	NA
WP_049824087.1\|2878841_2879237_+	hypothetical protein	NA	NA	NA	NA
WP_011789801.1\|2879230_2879395_+	DUF1317 family protein	NA	NA	NA	NA
WP_011789802.1\|2879404_2879989_+	hypothetical protein	NA	NA	NA	NA
WP_011789803.1\|2879985_2880705_+	hypothetical protein	A0A076G6Q2	Escherichia_phage	1.8e-33	39.0
WP_011789804.1\|2880701_2881025_+	hypothetical protein	A0A2I7RQ60	Vibrio_phage	6.8e-09	42.2
WP_041408214.1\|2881027_2881381_+	hypothetical protein	NA	NA	NA	NA
WP_011789806.1\|2881382_2882267_+	phage N-6-adenine-methyltransferase	H6WCM2	Enterobacteria_phage	6.0e-31	42.8
WP_011789807.1\|2882254_2883925_+	type II DNA modification methyltransferase	A0A1I9KFD6	Aeromonas_phage	7.5e-168	54.9
WP_011789808.1\|2883933_2884170_+	hypothetical protein	A0A0E3TAK6	Staphylococcus_phage	1.8e-14	53.9
WP_011789809.1\|2884162_2884954_+	HNH endonuclease	NA	NA	NA	NA
WP_011789810.1\|2884950_2885076_+	hypothetical protein	NA	NA	NA	NA
WP_041408215.1\|2885075_2885348_+	hypothetical protein	NA	NA	NA	NA
WP_041408216.1\|2885928_2886123_+	hypothetical protein	NA	NA	NA	NA
WP_011789813.1\|2886119_2887328_-\|integrase	tyrosine-type recombinase/integrase	K7P7J2	Enterobacteria_phage	1.5e-88	41.7
2887536:2887554	attR	NA	NA	NA	NA

DBSCAN-SWA_9

3060711 : 3071605

Streptococcus_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011789963.1\|3060711_3061746_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	4.0e-10	23.4
WP_011789965.1\|3062818_3063838_+	sensor domain-containing diguanylate cyclase	G3MA91	Bacillus_virus	7.2e-12	30.1
WP_011789966.1\|3063944_3066620_+	FAD-binding protein	A0A0B5JBT9	Pandoravirus	1.1e-24	39.5
WP_041408221.1\|3066790_3067324_+	lipocalin	A0A1W6JNX6	Morganella_phage	2.3e-46	50.9
WP_083758266.1\|3067430_3069023_-	ABC-F family ATPase	A0A2K9L0W2	Tupanvirus	1.1e-56	27.9
WP_011789969.1\|3069370_3071605_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.5e-91	34.6

DBSCAN-SWA_10

3298308 : 3341257

Pseudoalteromonas_phage(66.67%)

integrase,capsid,tail,terminase,transposase,portal

attL 3308049:3308086|attR 3342808:3342845

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011790140.1\|3298308_3300078_-\|portal	portal protein	NA	NA	NA	NA
WP_011787758.1\|3300241_3301852_-\|transposase	IS1634-like element ISSpu7 family transposase	NA	NA	NA	NA
WP_011790141.1\|3302104_3303838_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_011790142.1\|3303901_3304114_-	hypothetical protein	NA	NA	NA	NA
WP_011790143.1\|3304159_3304951_-	hypothetical protein	NA	NA	NA	NA
WP_025007415.1\|3305570_3306062_+	outer membrane protein assembly factor BamE	NA	NA	NA	NA
WP_011790145.1\|3306140_3306473_-	RnfH family protein	NA	NA	NA	NA
WP_011790146.1\|3306462_3306900_-	type II toxin-antitoxin system RatA family toxin	NA	NA	NA	NA
WP_011790147.1\|3307174_3307666_+	SsrA-binding protein SmpB	NA	NA	NA	NA
3308049:3308086	attL	NA	NA	NA	NA
WP_011790148.1\|3308837_3309233_-	hypothetical protein	NA	NA	NA	NA
WP_157037409.1\|3309660_3310197_-	hypothetical protein	A0A1L5C2B1	Pseudoalteromonas_phage	8.0e-71	74.6
WP_011790150.1\|3310403_3311093_-	hypothetical protein	A0A2I7RNK1	Vibrio_phage	4.5e-66	48.9
WP_011790151.1\|3311092_3311620_-	hypothetical protein	A0A1L5C2B6	Pseudoalteromonas_phage	6.9e-43	71.3
WP_011790152.1\|3311620_3314272_-	hypothetical protein	A0A1L5C2D7	Pseudoalteromonas_phage	1.3e-100	61.2
WP_041408232.1\|3314308_3314941_-	hypothetical protein	A0A1L5C2C5	Pseudoalteromonas_phage	6.5e-64	64.2
WP_011790154.1\|3314940_3316140_-	hypothetical protein	A0A1L5C2D1	Pseudoalteromonas_phage	1.3e-166	73.1
WP_011790155.1\|3316139_3316472_-	DUF2590 family protein	A0A1L5C2D6	Pseudoalteromonas_phage	2.5e-38	74.1
WP_011790156.1\|3316468_3318217_-\|tail	phage tail tape measure protein	A0A1L5C2B2	Pseudoalteromonas_phage	4.3e-190	61.2
WP_011790157.1\|3318419_3318683_-	hypothetical protein	A0A1L5C2C7	Pseudoalteromonas_phage	1.1e-20	59.1
WP_011790158.1\|3318679_3318943_-	hypothetical protein	A0A1L5C2D5	Pseudoalteromonas_phage	9.8e-14	50.6
WP_011790160.1\|3319566_3320115_-	N-acetylmuramidase	A2I317	Vibrio_virus	3.0e-49	52.2
WP_011790161.1\|3320116_3320320_-	conjugal transfer protein TraR	R9TMS3	Vibrio_phage	6.4e-05	47.4
WP_011790162.1\|3320350_3320806_-	DUF2597 family protein	A0A1L5C2D0	Pseudoalteromonas_phage	1.1e-60	79.1
WP_011790163.1\|3320818_3321925_-	DUF2586 family protein	A0A1L5C2B3	Pseudoalteromonas_phage	2.1e-158	76.6
WP_011790164.1\|3321927_3322590_-	hypothetical protein	A0A1L5C2C4	Pseudoalteromonas_phage	1.7e-75	65.9
WP_011790165.1\|3322586_3323075_-	hypothetical protein	A0A1L5C2C9	Pseudoalteromonas_phage	1.4e-58	70.7
WP_011790166.1\|3323071_3323545_-	hypothetical protein	A0A1L5C2A5	Pseudoalteromonas_phage	3.8e-48	65.6
WP_083758270.1\|3323671_3324322_-	hypothetical protein	A0A1L5C2B7	Pseudoalteromonas_phage	9.7e-71	70.9
WP_011790168.1\|3324363_3324966_-	hypothetical protein	A0A1L5C2C8	Pseudoalteromonas_phage	1.7e-08	49.0
WP_011790169.1\|3325043_3326087_-\|capsid	phage major capsid protein, P2 family	A0A1L5C2B0	Pseudoalteromonas_phage	1.3e-130	69.7
WP_011790170.1\|3326136_3327057_-\|capsid	phage capsid protein	A5X9H4	Aeromonas_virus	1.4e-35	41.5
WP_011790171.1\|3327260_3329069_+\|terminase	terminase	A0A1L5C295	Pseudoalteromonas_phage	1.0e-282	78.7
WP_011790172.1\|3329050_3330097_+\|portal	phage portal protein	A0A1L5C2C1	Pseudoalteromonas_phage	4.6e-139	73.9
WP_011790173.1\|3330134_3330491_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_011790174.1\|3330501_3330756_-	prevent-host-death protein	NA	NA	NA	NA
WP_011790175.1\|3331009_3331258_+	ogr/Delta-like zinc finger family protein	R9TNQ2	Vibrio_phage	2.4e-22	63.0
WP_157037394.1\|3331254_3331395_-	hypothetical protein	NA	NA	NA	NA
WP_011790176.1\|3332203_3334441_-	replication endonuclease	A0A2P1CKY6	Pseudoalteromonas_phage	2.0e-75	42.1
WP_011790177.1\|3334444_3335071_-	hypothetical protein	A0A067ZG73	Vibrio_phage	1.6e-41	42.6
WP_011790178.1\|3335067_3335361_-	hypothetical protein	NA	NA	NA	NA
WP_011790179.1\|3335335_3335575_-	hypothetical protein	NA	NA	NA	NA
WP_041408233.1\|3335614_3335809_-	hypothetical protein	NA	NA	NA	NA
WP_011790180.1\|3335818_3336385_-	hypothetical protein	A5X9F7	Aeromonas_virus	3.5e-16	36.3
WP_011790181.1\|3336500_3336701_-	hypothetical protein	Q1I116	Pasteurella_virus	1.2e-08	43.3
WP_011790182.1\|3336799_3337492_+	bacteriophage CI repressor	A0A1D9C9M6	Salinivibrio_phage	7.5e-13	23.5
WP_011790183.1\|3337503_3337929_+	hypothetical protein	NA	NA	NA	NA
WP_011790184.1\|3338015_3338975_+	FRG domain-containing protein	NA	NA	NA	NA
WP_011790185.1\|3338995_3339601_+	hypothetical protein	NA	NA	NA	NA
WP_011790186.1\|3339610_3340228_+	hypothetical protein	NA	NA	NA	NA
WP_011790187.1\|3340237_3341257_+\|integrase	tyrosine-type recombinase/integrase	A0A1S6L016	Salmonella_phage	1.7e-114	58.9
3342808:3342845	attR	NA	NA	NA	NA

DBSCAN-SWA_11

3350167 : 3360671

uncultured_Caudovirales_phage(25.0%)

transposase,integrase,head

attL 3347433:3347446|attR 3359250:3359263

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3347433:3347446	attL	NA	NA	NA	NA
WP_011790197.1\|3350167_3350515_-	metalloregulator ArsR/SmtB family transcription factor	A0A2H4J145	uncultured_Caudovirales_phage	4.4e-30	55.8
WP_011790198.1\|3350507_3350924_-	arsenate reductase ArsC	A0A2H4J437	uncultured_Caudovirales_phage	1.5e-32	51.1
WP_011790199.1\|3351021_3351339_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011790200.1\|3351561_3352560_+	permease	NA	NA	NA	NA
WP_011790201.1\|3352842_3353604_-	LexA family transcriptional regulator	A5X9F5	Aeromonas_virus	1.0e-26	32.4
WP_011790202.1\|3353749_3354073_+	transcriptional regulator	A0A2P9JZG5	Alteromonadaceae_phage	5.6e-11	46.8
WP_011790203.1\|3354190_3354679_+	hypothetical protein	Q6QID6	Burkholderia_phage	1.8e-45	53.5
WP_083758271.1\|3354620_3356855_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	A0A0M4U788	Ralstonia_phage	3.3e-78	39.6
WP_011790205.1\|3356899_3357619_+	ATP-binding protein	A0A0M4UT94	Ralstonia_phage	2.1e-10	28.1
WP_041408236.1\|3357621_3357921_+	hypothetical protein	NA	NA	NA	NA
WP_049824076.1\|3357907_3358225_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011790208.1\|3358499_3358712_+	hypothetical protein	NA	NA	NA	NA
WP_011790209.1\|3358716_3358959_+	hypothetical protein	NA	NA	NA	NA
WP_011790210.1\|3359145_3359580_+	hypothetical protein	NA	NA	NA	NA
3359250:3359263	attR	NA	NA	NA	NA
WP_011790211.1\|3359765_3360671_+\|head	head protein	A0SMP3	Pseudomonas_virus	6.9e-83	53.0

Anti-CRISPR protein detection

Acr_ID: NC_008750.1|WP_041408206.1|2864570_2864822_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_008750.1|WP_041408206.1|2864570_2864822_-|hypothetical-protein

2864570_2864822_-

83 aa aa

2839300-2887328

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_008750_5	TypeI-F	5.4\|2522786\|32\|NC_008750\|CRISPRCasFinder,CRT	2522786-2522817	32	2870037-2870068	1

1. spacer 5.4|2522786|32|NC_008750|CRISPRCasFinder,CRT matches to NC_008750 position: 2870037-2870068, mismatch: 1

accaaagcgattgctaaaatcacggctgtaca	CRISPR spacer
accaaaccgattgctaaaatcacggctgtaca	Protospacer
****** *************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_008750

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information