CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_008639	Chlorobium phaeobacteroides DSM 266, complete sequence	7 crisprs	csa3,cas3,cas2,cas1,cas4,cas7,cas8c,cas5,cas3HD,WYL,RT,DEDDh,cas6,csx1,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx15	1	17	11	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_008639_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008639_1

286609-286778

Orphan

Consensus_repeat	Method
ATGTAACTTAACGAATTCAGGAACGTCCCTAAGGGTGTTCCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008639_1

>merge|NC_008639|1|286609-286778|CRISPRCasFinder
ATGTAACTTAACGAATTCAGGAACGTCCCTAAGGGTGTTCCTATGTAACTTAACGAATTCAGGAACGTCCCTAAGGGTGTTCCTCGGCGGTGTGTCAGATTATCAAAACCGGAACCGATTCTTGTCGCATGTAACTTAACGAATTCAGGAACGTCCCTAAGGGTGTTCCT

>NC_008639|1|1|286609-286778|CRISPRCasFinder
ATGTAACTTAACGAATTCAGGAACGTCCCTAAGGGTGTTCCT	ATGTAACTTAACGAATTCAGGAACGTCCCTAAGGGTGTTCCTCGGCGGTGTGTCAGATTATCAAAACCGGAACCGATTCTTGTCGC
ATGTAACTTAACGAATTCAGGAACGTCCCTAAGGGTGTTCCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_008639.1\|WP_011744156.1\|279378_279585_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|213767
NC_008639.1\|WP_011744163.1\|288423_288852_+\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011744159.1\|283582_283807_-\|addiction-module-protein	unknown	unknown	gnl\|CDD\|378247
NC_008639.1\|WP_011744168.1\|293206_293464_+\|DUF2442-domain-containing-protein	unknown	unknown	gnl\|CDD\|378424
NC_008639.1\|WP_011744166.1\|292107_292848_+\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_041467467.1\|292952_293210_+\|DUF4160-domain-containing-protein	unknown	unknown	gnl\|CDD\|379344
NC_008639.1\|WP_081428200.1\|286941_287211_+\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011744162.1\|287224_288241_+\|integron-integrase	unknown	unknown	gnl\|CDD\|131303
NC_008639.1\|WP_011744153.1\|277732_278035_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|224069
NC_008639.1\|WP_049751720.1\|281203_281476_+\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011744154.1\|278090_279047_-\|HipA-domain-containing-protein	unknown	unknown	gnl\|CDD\|377920
NC_008639.1\|WP_011743933.1\|290523_291930_-\|IS1380-like-element-ISCph6-family-transposase	unknown	unknown	gnl\|CDD\|379340
NC_008639.1\|WP_011744158.1\|283295_283586_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	unknown
NC_008639.1\|WP_011744155.1\|279051_279375_-\|HipA-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|274416
NC_008639.1\|WP_011744160.1\|283849_285070_-\|ISL3-family-transposase	unknown	unknown	gnl\|CDD\|376574
NC_008639.1\|WP_011744164.1\|289089_289329_+\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011744157.1\|279919_281137_-\|phosphoserine-phosphatase-SerB	unknown	unknown	gnl\|CDD\|319803
NC_008639.1\|WP_011744165.1\|289481_289934_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372116
NC_008639.1\|WP_150081045.1\|293771_294203_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235087
NC_008639.1\|WP_011744152.1\|277186_277681_+\|ferredoxin-family-protein	unknown	unknown	gnl\|CDD\|224069

Protein	Function_ID	Function_description	E-value
NC_008639.1\|WP_011744156.1\|279378_279585_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|213767	TIGR03070, couple_hipB, transcriptional regulator, y4mF family. Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions].	1.79152e-21
NC_008639.1\|WP_011744159.1\|283582_283807_-\|addiction-module-protein	gnl\|CDD\|378247	pfam09720, Unstab_antitox, Putative addiction module component. This entry defines several short bacterial proteins, typically about 75 amino acids long, which are always found as part of a pair (at least) of small genes. The other protein in the pair always belongs to a family of plasmid stabilisation proteins (IPR007712). It is likely that this protein and its partner comprise some form of addiction module - a pair of genes consisting of a stable toxin and an unstable antitoxin which mediate programmed cell death - although these gene-pairs are usually found on the bacterial main chromosome.	3.99549e-13
NC_008639.1\|WP_011744168.1\|293206_293464_+\|DUF2442-domain-containing-protein	gnl\|CDD\|378424	pfam10387, DUF2442, Protein of unknown function (DUF2442). This family of bacterial and fungal proteins has several members annotated as being putative molybdopterin-guanine dinucleotide biosynthesis protein A; however this could not be verified. Hence the function is not known. This family also includes the DUF3532 that was found to be related and was merged into this family. Members of this family also fall into the NE0471 N-terminal domain-like superfamily, a family of proteins with a unique fold in SCOP:143880.	3.89826e-09
NC_008639.1\|WP_041467467.1\|292952_293210_+\|DUF4160-domain-containing-protein	gnl\|CDD\|379344	pfam13711, DUF4160, Domain of unknown function (DUF4160).	1.72998e-19
NC_008639.1\|WP_011744153.1\|277732_278035_+\|ferredoxin-family-protein	gnl\|CDD\|224069	COG1146, COG1146, Ferredoxin [Energy production and conversion].	4.95616e-08
NC_008639.1\|WP_011744157.1\|279919_281137_-\|phosphoserine-phosphatase-SerB	gnl\|CDD\|319803	cd07500, HAD_PSP, phosphoserine phosphatase (PSP), similar to Methanococcus Jannaschii PSP and Saccharomyces cerevisiae SER2p. This family includes Methanococcus jannaschii PSP, and Saccharomyces cerevisiae phosphoserine phosphatase SER2p, EC 3.1.3.3, which participates in a pathway whereby serine and glycine are synthesized from the glycolytic intermediate 3-phosphoglycerate; phosphoserine phosphatase catalyzes the hydrolysis of phospho-L-serine to L-serine and inorganic phosphate, the third reaction in this pathway. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.79349e-102
NC_008639.1\|WP_011744154.1\|278090_279047_-\|HipA-domain-containing-protein	gnl\|CDD\|377920	pfam07804, HipA_C, HipA-like C-terminal domain. The members of this family are similar to a region close to the C-terminus of the HipA protein expressed by various bacterial species. This protein is known to be involved in high-frequency persistence to the lethal effects of inhibition of either DNA or peptidoglycan synthesis. When expressed alone, it is toxic to bacterial cells, but it is usually tightly associated with HipB, and the HipA-HipB complex may be involved in autoregulation of the hip operon. The hip proteins may be involved in cell division control and may interact with cell division genes or their products.	8.50322e-64
NC_008639.1\|WP_011743933.1\|290523_291930_-\|IS1380-like-element-ISCph6-family-transposase	gnl\|CDD\|379340	pfam13701, DDE_Tnp_1_4, Transposase DDE domain group 1. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	0
NC_008639.1\|WP_011744155.1\|279051_279375_-\|HipA-N-terminal-domain-containing-protein	gnl\|CDD\|274416	TIGR03071, couple_hipA, HipA N-terminal domain. Although Pfam models pfam07805 and pfam07804 currently are called HipA-like N-terminal domain and HipA-like C-terminal domain, respectively, those models hit the central and C-terminal regions of E. coli HipA but not the N-terminal region. This model hits the N-terminal region of HipA and its homologs, and also identifies proteins that lack match regions for pfam07804 and pfam07805.	2.83836e-32
NC_008639.1\|WP_011744160.1\|283849_285070_-\|ISL3-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.51474e-92
NC_008639.1\|WP_011744162.1\|287224_288241_+\|integron-integrase	gnl\|CDD\|131303	TIGR02249, Integrase/recombinase_E2_protein., integron integrase. Members of this family are integrases associated with integrons (and super-integrons), which are systems for incorporating and expressing cassettes of laterally transferred DNA. Incorporation occurs at an attI site. A super-integron, as in Vibrio sp., may include over 100 cassettes. This family belongs to the phage integrase family (pfam00589) that also includes recombinases XerC (TIGR02224) and XerD (TIGR02225), which are bacterial housekeeping proteins. Within this family of integron integrases, some are designated by class, e.g. IntI4, a class 4 integron integrase from Vibrio cholerae N16961. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Other].	1.34222e-166
NC_008639.1\|WP_011744165.1\|289481_289934_+\|hypothetical-protein	gnl\|CDD\|372116	pfam12449, DUF3684, Protein of unknown function (DUF3684). This domain family is found in eukaryotes, and is typically between 1072 and 1090 amino acids in length.	0.0015684
NC_008639.1\|WP_150081045.1\|293771_294203_+\|hypothetical-protein	gnl\|CDD\|235087	PRK02925, PRK02925, glucuronate isomerase; Reviewed.	0.00121367
NC_008639.1\|WP_011744152.1\|277186_277681_+\|ferredoxin-family-protein	gnl\|CDD\|224069	COG1146, COG1146, Ferredoxin [Energy production and conversion].	6.6237e-06

>NC_008639.1|WP_011744160.1|283849_285070_-|ISL3-family-transposase
MNDLTLFQMALGLESPWYVSSSSFDVDQKRLDIRIDFKPGSTFCCPQCGREGVKAYDTSEATWRHLNFFQHEAYLTVRVPRISCPECGILKLQSFPWSRRESGFTLLFEAMIMIMAKSMPVKAIAAIVGEHDTRIWRIINHYVEKAREQEDHSAVTMVGVDETSSKRGHNYVSLFVDLAVSKVLFATEGKDAATVKRFSEDLAAHKGDPALITEFCSDMSPAFIKGVADNFTNAQLTFDKFHIMQVINNAVDEVRRQEQKERPELQRSRYIWLKNQNNLKASQRKRLDELSLPRLNLKTTRAYRMRLTFQEFFEQPQVLVEAFLKKWYFWATHSQLQPMKEAAYTIKRHWSGILRWFTSRINNGVLEGINSLIQAAKARARGYRTTKNLINMIYLISGKLNFGLPT
>NC_008639.1|WP_011744159.1|283582_283807_-|addiction-module-protein
MNTKQLIDKAVSLPVEERALVVDSLLRSLNQPESEIDKKWSQEAKRRLAELRSGQVQAIPGDEVFAEVWKKFES
>NC_008639.1|WP_011744158.1|283295_283586_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MIFSFHPEAKEEFDKAIEYYENIAPGLGYDFALEVHSAIKRSIEHPNAWAVLYEDVRRSLVRRFPYGVLYSKEPAEIFILAVMNLHRNPGYWKKRK
>NC_008639.1|WP_049751720.1|281203_281476_+|hypothetical-protein
MEPFIAVISHDNSARLLNNNIALQNIKIVLFQEPSKTGAGKITERQASGAGRMSVPYSVTADGATLFCYTFRAPLKSVMSDQSARRTEPR
>NC_008639.1|WP_011744157.1|279919_281137_-|phosphoserine-phosphatase-SerB
MSELLLINLTGLDKPGLTSKITAILADARVPVLDIGQAVIHNHLSLGMLVEVPKESASSPVLKDLLFCAHTLGIQISFTPVADEEYDRWVGEQGKPRYLLSLLSRKISAEQLKRVSSIVAEHDLNIDTISRLSGRIPLDNGDNHTRACVEFSLRGTLSDENLFREQLLAITDSLGIDIAFQEDNIFRRNRRMVVFDMDSTLITSEVIDELALEAGVGEEVSAITEQAMRGELDFNESLQRRVAQLKGLDEHVMESIAARLQLTEGAERLFGNLKRLGYKTAILSGGFTYFGHYLQKKLSIDYVYANTLEIENGCLTGRVLGRVVDGARKAELLELLAEKENISLEQTVAVGDGANDLPMLGKAGLGIAFRAKPIVRERAKQAISTLGLDAILYLMGFRDRDELSE
>NC_008639.1|WP_011744156.1|279378_279585_-|helix-turn-helix-transcriptional-regulator
MKDIAEFVRDRRKALGMTQPELAEKAGTGLRFIRDLEQGKKTLRMDKVNQVLALFGFVLAPVSPEREA
>NC_008639.1|WP_011744155.1|279051_279375_-|HipA-N-terminal-domain-containing-protein
MQKAEIRYLDRTAGWFIQDEEGFHFLYDQAYLDSKDARPVSLTLPLRAAAYSSRTMFPFFDGLIPEGWLLAVAERNWKLDPRDRMGLLLNCCRDCIGAVSVHPVIME
>NC_008639.1|WP_011744154.1|278090_279047_-|HipA-domain-containing-protein
MDRRCLYCYEPLASGEGDFHRKCSRKMFGTPLPPELPYDENQLEELALEVIRSQTAITGVQPKLSLHLEPAGKAHAPQRFTIVGLWGGYILKPPSQRFRQLPEIEDLTMRMAEAARIDTVPHSLIRMRSGALAYLTRRIDRTGNGKLHMEDMCQITGRLTENKYHGSYEQIAKAIHRYSANPGLDVINFFEVVLFCFLSGNADMHLKNFSLIDIEAKGGYSLAPAYDLVSTGLVMPSDKEDLALTLDGKKTRITLNDFRAAFGVLTIDEVVQERMFRKFRNVLPLWDLLIEKSFLDYENQAAYKELIRKKCHQIRLDA
>NC_008639.1|WP_011744153.1|277732_278035_+|ferredoxin-family-protein
MSGLPSPSKKKKRLLAPREEIAWFPVIDTAACNGCGDCEGFCKPGVFALGEPEGVKRARMTVANPWNCIVLCTRCEPVCPSGAITLPRPEDFERFVEYVD
>NC_008639.1|WP_011744152.1|277186_277681_+|ferredoxin-family-protein
MLVFDCFFGRCEKPSCEGCALKLVRSLRLALKSRAMQKDEEFAVETACSPEKPAMVALQAKTTSHKQDATKKRKRLLAPREEIPWYPTIKPELCNGCGDCKVLCKPGVFELGAPDPSGIHRPKLVVAHPYKCLVLCTRCVPICTSGAIILPPKEDFERFVEYLD
>NC_008639.1|WP_081428200.1|286941_287211_+|hypothetical-protein
MVPFIAVIFHDNPARLLNNNIALQNIKIVLFQEPSKTGAGKITERQASGAGRISVVCSVVIGWLVPYYFDGSTLFCYTFSKLLLRQGKH
>NC_008639.1|WP_011744162.1|287224_288241_+|integron-integrase
MVADSQTVLQSTVNSQSLQHGPKLLELFREAMRVRHYSRRTEETYCSWVKRYVHFHNMRHPKEMREPEINAFLTHLAVEEKVSASTQNQALSALLFLYRHVIGKEIGDLGHLIRARKPSHLPVVLTRDEVKALLVQLAGVKWLMASLMYGAGLRLMECLRLRVQDIDFSSNEILVRDGKGAKDRITMLPESLKKPLADHLKQIKSLHDKDLAEGWGRVLLPGALDRKYPNAPAEWRWQWVFPQEHRWKNAKTGEEGRHHMDESLIQKAVKAAVFHAQLTKRATCHTFRHSFATHLLEGGYDIRTVQELLGHNDVRTTMIYTHVLNRGPSGVRSPVDCL
>NC_008639.1|WP_011744163.1|288423_288852_+|hypothetical-protein
MNNELRTKLIATALEWQDRYGVAPQITTPLSEYDAAMLVGMPEHEYSAYMQDITAVNKGSDFIYRNVRYQVKGNRPSGKPGSKVTMVPKATNYEWDKLIWVLYDKFYVIQEAWLWDVAEYKQKFHNIKRLSPSHYREGVQLA
>NC_008639.1|WP_011744164.1|289089_289329_+|hypothetical-protein
MVKLDYADYKFTVKEGSPSVSGADDAPVSLCCEPRTSELSIVGSGHLSIHLKKGISCDDAQEIAKNLEQWIEKISYVKG
>NC_008639.1|WP_011744165.1|289481_289934_+|hypothetical-protein
MKSSLIRFAIILFVFLSGCGTKEEPTAQEIAEAQLKETPAYKDYSADANTAFLIEVKERLKAPSGADFPWDDLPKEVTTKGVKLSDMSPYLRKVIKEARKLKKENAVRVYQKDSYVDADNSFGAKIRQRYLGTFIIYTEFGYTKSFVEFY
>NC_008639.1|WP_011743933.1|290523_291930_-|IS1380-like-element-ISCph6-family-transposase
MQLPYTNIHTDQPNQQALFPDCFEVSVAPVKGKKVVLDFQGGNATSDAGVLLLKEVESMTRIVPKLADCIADSRRTSSVMHSIPDLIAQRVYQIACGYEDGNDSNSMRKDPALKMALNRLPESGDDLASQPTFSRLENMVTRPELYRMAVGFLDHFLDSYTEAPRVIVLDFDDTEDVVHGKQQLALFNGYHQETCYQPLHVFEGLTGKLIASILRPGRRPTGKEIVSYVKRIVRHIRSRWPETIIVYRGDSHYGVPEVYSFLAREQNCYSVTGLGGNDVLLRSVKDIIEEVKKHGAGYRRYHTFQYQARSWKETRRVVAKVEMTEKGLNVRFISTDMQEAKAKTLYEQIYSARGNDELYIKAHKTFMKSDRTSCHRFLANQFRVFLHSAAYVLVHAFQTNLLRGTALATATFETIRLKLLKIGAKVIEMKTRIKVHLPTSYPYKPILNKCFAVLEHLRSVPWPSTAIP
>NC_008639.1|WP_011744166.1|292107_292848_+|hypothetical-protein
MIIQDYSEHIENFENYLKSKLASIDEISGDNNVLFKKILYVSFLDSLSSCVYPGRGNKERFVSMLERFSKWEDRDRVSLPHLGKFVQIISDPLLEQARKYVTPKLKTWQERSCYVISISEDPIIDEILDKSWKTNKETGIHVSLTDFKHISLLYQLRNALVHQFQSRGDEMGNLRQLDHPYYQRVQIFNGTLEDMKPVRFELVYPTQFLKSLSEKTLENVVDYLKDGNINPFPHYYAGDYWITELN
>NC_008639.1|WP_041467467.1|292952_293210_+|DUF4160-domain-containing-protein
MFYGILIRMFFRDAEKHHVPHIHADYQGNVAVYSIPEGTLLAGLLPPNKHKLVVAWIEIHHEDLLADWNLAVNGKKPFPIKGLDQ
>NC_008639.1|WP_011744168.1|293206_293464_+|DUF2442-domain-containing-protein
MRIAELHPQPDWVLSIVSEDGRVGRFDVTPYLEYEAFEELRDHGEFIKVINGGYFVEWECGADLSADTIEAQWKVVGKAEQQNTV
>NC_008639.1|WP_150081045.1|293771_294203_+|hypothetical-protein
MSVIVGTALSIAANILSHSIIQNRSKFRWKAGLPLYVGTMVYLWFVLELLSSSSTDRPFGIAFSINAIYLVVSCFRASLQVTSFSAVTKTAVYLQVAIFVLTLPFTDAFWGPQSADVEASIAFNGIIIAALMFMTKGYREGGV

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Crispr_ID: NC_008639_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008639_2

1622087-1622714

TypeI

I-C

Consensus_repeat	Method
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	PILER-CR
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CRISPRCasFinder
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CRT

9 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3,cas3HD

The CRISPR arrays of NC_008639_2

>merge|NC_008639|2|1622087-1622714|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGACTTCGACTCGATGCGGATGCCGATGATGAGACGTCAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCGATGCGGCGAAAGCTCAGCAAATTATCTTAAAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTTCGATTGTGTCGCCGCTGTGATTTCGATTGTGTCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGGCGGGAACACGATGACCATATTCCTGATATCGGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTCCCCACTTATAATACGGCTCCCCGTCAGTTTCACGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGGCCGTGGAGCCTTGCTGAAAACGTAGGAGTTAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTAGATGTGTTGTGTTTGTTGATTGCCAGACAGAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTTGCAAATCTTTAAGCGTCAGTCCGCCGGTATACTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTAAATGATATGGATCTCGACCTGTTTAGTCTGTTTCAATCCACGCGCCCGCAGGGGGCGCGAC

>NC_008639|2|1|1622087-1622714|PILER-CR
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCGACTCGATGCGGATGCCGATGATGAGACGTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGATGCGGCGAAAGCTCAGCAAATTATCTTAAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCGATTGTGTCGCCGCTGTGATTTCGATTGTGTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCGGGAACACGATGACCATATTCCTGATATCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCCCCACTTATAATACGGCTCCCCGTCAGTTTCAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCCGTGGAGCCTTGCTGAAAACGTAGGAGTTAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTAGATGTGTTGTGTTTGTTGATTGCCAGACAGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTGCAAATCTTTAAGCGTCAGTCCGCCGGTATACT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTAAATGATATGGATCTCGACCTGTTTAGTCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC

>NC_008639|2|2|1622087-1622714|CRISPRCasFinder
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCGACTCGATGCGGATGCCGATGATGAGACGTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGATGCGGCGAAAGCTCAGCAAATTATCTTAAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCGATTGTGTCGCCGCTGTGATTTCGATTGTGTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCGGGAACACGATGACCATATTCCTGATATCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCCCCACTTATAATACGGCTCCCCGTCAGTTTCAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCCGTGGAGCCTTGCTGAAAACGTAGGAGTTAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTAGATGTGTTGTGTTTGTTGATTGCCAGACAGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTGCAAATCTTTAAGCGTCAGTCCGCCGGTATACT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTAAATGATATGGATCTCGACCTGTTTAGTCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC

>NC_008639|2|1|1622087-1622714|CRT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCGACTCGATGCGGATGCCGATGATGAGACGTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGATGCGGCGAAAGCTCAGCAAATTATCTTAAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCGATTGTGTCGCCGCTGTGATTTCGATTGTGTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCGGGAACACGATGACCATATTCCTGATATCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCCCCACTTATAATACGGCTCCCCGTCAGTTTCAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCCGTGGAGCCTTGCTGAAAACGTAGGAGTTAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTAGATGTGTTGTGTTTGTTGATTGCCAGACAGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTGCAAATCTTTAAGCGTCAGTCCGCCGGTATACT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTAAATGATATGGATCTCGACCTGTTTAGTCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008639.1\|WP_041467258.1\|1620638_1620851_+\|YgiT-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|274806
NC_008639.1\|WP_011745273.1\|1623619_1625194_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
NC_008639.1\|WP_011745264.1\|1613642_1614518_-\|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl\|CDD\|224600
NC_008639.1\|WP_011745274.1\|1633226_1633517_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_008639.1\|WP_011745265.1\|1614835_1615459_-\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NC_008639.1\|WP_011745271.1\|1620981_1621947_-\|transposase	unknown	unknown	gnl\|CDD\|376616
NC_008639.1\|WP_011745276.1\|1634548_1635193_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NC_008639.1\|WP_011745277.1\|1635195_1636296_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|274216
NC_008639.1\|WP_011745280.1\|1638793_1640797_-\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_008639.1\|WP_011745279.1\|1638057_1638771_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	gnl\|CDD\|187534
NC_008639.1\|WP_011745263.1\|1613190_1613493_-\|Dabb-family-protein	unknown	unknown	gnl\|CDD\|214884
NC_008639.1\|WP_011745275.1\|1633520_1634552_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_008639.1\|WP_011745269.1\|1619046_1620012_-\|transposase	unknown	unknown	gnl\|CDD\|376616
NC_008639.1\|WP_011745278.1\|1636336_1638061_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|187887
NC_008639.1\|WP_011745267.1\|1615990_1616458_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745268.1\|1616729_1617488_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NC_008639.1\|WP_041467605.1\|1622858_1623599_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|366760
NC_008639.1\|WP_011745281.1\|1640783_1641035_-\|CRISPR-associated-endonuclease-Cas3''	cas3HD	cd09641_cas3HD_CAS-I	gnl\|CDD\|193608
NC_008639.1\|WP_011745270.1\|1620312_1620642_+\|DUF4258-domain-containing-protein	unknown	unknown	gnl\|CDD\|379454
NC_008639.1\|WP_011745266.1\|1615473_1615782_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008639.1\|WP_041467258.1\|1620638_1620851_+\|YgiT-type-zinc-finger-protein	gnl\|CDD\|274806	TIGR03831, hypothetical_protein, YgiT-type zinc finger domain. This domain model describes a small domain with two copies of a putative zinc-binding motif CXXC (usually CXXCG). Most member proteins consist largely of this domain or else carry an additional C-terminal helix-turn-helix domain, resembling that of the phage protein Cro and modeled by pfam01381.	5.69506e-09
NC_008639.1\|WP_011745273.1\|1623619_1625194_-\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.7075e-13
NC_008639.1\|WP_011745264.1\|1613642_1614518_-\|D-alanyl-D-alanine-carboxypeptidase	gnl\|CDD\|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	4.18858e-63
NC_008639.1\|WP_011745274.1\|1633226_1633517_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.53254e-34
NC_008639.1\|WP_011745265.1\|1614835_1615459_-\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	1.01826e-44
NC_008639.1\|WP_011745271.1\|1620981_1621947_-\|transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	3.111e-09
NC_008639.1\|WP_011745276.1\|1634548_1635193_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	5.02087e-47
NC_008639.1\|WP_011745280.1\|1638793_1640797_-\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.59513e-56
NC_008639.1\|WP_011745279.1\|1638057_1638771_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	5.7417e-103
NC_008639.1\|WP_011745263.1\|1613190_1613493_-\|Dabb-family-protein	gnl\|CDD\|214884	smart00886, Dabb, Stress responsive A/B Barrel Domain. The function of this domain is unknown, but it is upregulated in response to salt stress in Populus balsamifera (balsam poplar). It is also found at the C-terminus of a fructose 1,6-bisphosphate aldolase from Hydrogenophilus thermoluteolus.It is found in the pA01 plasmid, which encodes genes for molybdopterin uptake and degradation of plant alkaloid nicotine. The structure of one has been solved and the domain forms an alpha-beta barrel dimer. Although there is a clear duplication within the domain it is not obviously detectable in the sequence.	3.91747e-23
NC_008639.1\|WP_011745275.1\|1633520_1634552_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NC_008639.1\|WP_011745269.1\|1619046_1620012_-\|transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	3.4388e-09
NC_008639.1\|WP_011745278.1\|1636336_1638061_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	0
NC_008639.1\|WP_011745277.1\|1635195_1636296_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|274216	TIGR02589, conserved_hypothetical_protein, CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csd2 protein of the Dvulg subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02590, the Csh2 protein of the Hmari CRISPR subtype.	3.04214e-133
NC_008639.1\|WP_011745268.1\|1616729_1617488_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	1.23779e-65
NC_008639.1\|WP_041467605.1\|1622858_1623599_-\|ATP-binding-protein	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	1.90385e-57
NC_008639.1\|WP_011745270.1\|1620312_1620642_+\|DUF4258-domain-containing-protein	gnl\|CDD\|379454	pfam14076, DUF4258, Domain of unknown function (DUF4258). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 95 and 124 amino acids in length.	1.45512e-18
NC_008639.1\|WP_011745281.1\|1640783_1641035_-\|CRISPR-associated-endonuclease-Cas3''	gnl\|CDD\|193608	cd09641, Cas3''_I, CRISPR/Cas system-associated protein Cas3''. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; HD-like nuclease, specifically digesting double-stranded oligonucleotides and preferably cleaving at G:C pairs; signature gene for Type I.	7.33345e-10

>NC_008639.1|WP_011745271.1|1620981_1621947_-|transposase
MPRGARLDVAGTLHHVIIRGIEQGSIVRDDTDRKMFLDRMGLLAASSGTSIYAFALMTNHAHILLKSGPNGLSGYMRRLLSWYAQYFNRRHQRVGHLFQNRYKSIICEEEAYFDKLVAYIHLNPLRAGLAETMQQLASYPWSGHAVLMNKVRYEWMDRDYVLRFFGSREGLARNAYLRFLEEELCIDREKELSGGGLVRSQGGWSKVQSMRKRGEKALGDERILGGDDFVRRVLKEGEEDKDALLPENERMKRFKEAVEQVCEDAGVTKTYLLSGSRGGKLPLLRKELAMKSVYEYGISLAETARQLGVTTNAVSYMLKSR
>NC_008639.1|WP_041467258.1|1620638_1620851_+|YgiT-type-zinc-finger-protein
MNCMYCKGNMERGIAPFHIDRKGYHITLDRIPAWVCTQCGEVYFDESEVEAIQEVLCTLDQRTEKMAKSA
>NC_008639.1|WP_011745270.1|1620312_1620642_+|DUF4258-domain-containing-protein
MTDYSDIVSSVKKSAAKRIIYLPHAVRQMSRPDRIILVAEVRNVVERGELVEDYPEDVRGHSCLLLGYKLDDTPIHVVCSPKGDYLAIITAYIPNPEEWECDYKRRRRR
>NC_008639.1|WP_011745269.1|1619046_1620012_-|transposase
MPRGARLDVAGTLHHVIIRGIEQGSIVRDDTDRKMFLDRMGLLAASSGTSIYAFALMTNHAHILLKSGPNGLSGYMRRLLSWYAQYFNRRHQRVGHLFQNRYKSIICEEEAYFDKLVAYIHLNPLRAGLAETMQQLASYPWSGHAVLMNKVRYEWMDRDYVLRFFGSREGLARNAYLRFLEEELCIDREKELSGGGLVRSQGGWSKVQSMRKRGEKALGDERILGGDDFVRRVLKEGEEDKDALLPENERMKRFKEAVEQVCEDAGITKTYFLSGSRGGKLPLLRKELAMKSVYEYGISLAETARQLGVTTNAVSYMLKSR
>NC_008639.1|WP_011745268.1|1616729_1617488_+|SagB/ThcOx-family-dehydrogenase
MNSTAIQTCRSFLKDTIRQTIDFSRTDQNLWIPPPPVEKPYSQDMKRIELPKIETLQTIGQIDLKTAIARRESCRTYSKTPLTLEELSLLLWATQGVRRKLDAGHALRTVPSAGCRHAFETYLCVLNVIGLEKGIYRYLPLEHQLLFEFDADNLEHKITRAALGQPFTGEAAVTFIWTAIPYRMEWRYGLAAHKVIALDAGHVCQNLYLAAEAIGAGTCAIAAYDQAAMDKLLNIDGEEEFTIYLAPVGKKR
>NC_008639.1|WP_011745267.1|1615990_1616458_-|hypothetical-protein
MAKQSLLQEMKKTFMLHAIAAHFSNGMIPVAVLYLLLTISTGDVFFERTVEHLIIIVLMAIPVSFFSGIYDWKKKYRGAKAPVFMKKIRLSGILFVLCALTVGIRLSTPDVMTGTGILHWVYIVLLLGMLPIVTLLGHYGGKLASQGRQQQPKAS
>NC_008639.1|WP_011745266.1|1615473_1615782_-|hypothetical-protein
MPVDHRSSRSLSEAFIDSVMSEACQPLYIGCFALLVRRIDGVSVRFGLQNLYGFMPFFAFAAEISFSQAWVCRKMQIALFIVDRLFLKLSVVNKMLEERKDV
>NC_008639.1|WP_011745265.1|1614835_1615459_-|LysE-family-translocator
MIDQHVLFMFFVSSVVLSLSPGPDNLFVMAQSARNGRLAGMMVTLGLCTGLVLHTLAVAFGLAALVAASAVAFTVLKFAGAAYLLFLAWKAFHADVEKDSSDVSQVERGKLYRRGIVMNISNPKVSLFFLAFLPQFADPKNGPLVPQLLFLGAIFIVAALLVFSLLFFVAGGAGARFRRSAKARRVVNRIAGTIFAGFALKLLFTER
>NC_008639.1|WP_011745264.1|1613642_1614518_-|D-alanyl-D-alanine-carboxypeptidase
MNRKDRMFRKSVLFLFSMFLASGISMPVYAALPVDSLLQPLQPPEIGSYILKETGSSKVFMVKDSEKTIQPASLTKILTSIIALESGQLDDEVVITKEATMVEPSKAGFKPGERILLRDLVKAAMVSSSNDAAFAIGIHLEGSVPRFVRKMNRKARDIGMRHSVFTNPAGFDKRVYAGNVSTAEDLVKLTEYAIRNRKFNEIASLESVLVTERSSNKIYLLKTHNKLLGKYPYAVGIKTGFTRSAGKCLIARAKKENKDMLLVLLDAKGDRWSIAEQMFESAFTPPFQAYQ
>NC_008639.1|WP_011745263.1|1613190_1613493_-|Dabb-family-protein
MVRHVVMWRLKEFALGNSRAVNAALLRDRLVGLRGLVTGMVALEAGVDYSGTASSFDVVLYSEFTDRVALESYQVHPEHEAVKAFVVEVSAERAVVDYEE
>NC_008639.1|WP_041467605.1|1622858_1623599_-|ATP-binding-protein
MNTQLTLDQLRSMNLYGMANAYEAAMTLPVHEQPAADMLLGKLVDAEQLFRKEQSTKRYLLQSKIRYPAILEQVHCNAARNLTRDQLLSLSDCSFIRRGENILITGATGCGKSYLACALGRQACSLGYRTLYFGMNRFLERIAQTKLDGTFVRVLNQIERTHLIILDDFGLQPLDATTRIALLQILEDRYGKQAIMITSQLPVAQWHDVIGEPTIADGIMDRLVGNAHRLELKGESLRRKKLDKNV
>NC_008639.1|WP_011745273.1|1623619_1625194_-|IS21-family-transposase
MANKALTMLQVRRILKLLMEECSQREIHRSTGIHRVTIKSYLHRFTSSGKPFSELYALSDYDLSVLVHPPRSTKTSDERYADLQPQLQRFSDELNKTNSHVTKQVLWEEYLQDRPTGYQYSQFCYHVDQYIKQHAVTMPQQHEPGYRLQIDFAGDPLWIIDPLTRERIKCPVLVCTLPCSSFFYVEPLSSCRQEHLIPALNRALAYFGGVPKNILSDNMKQVVTTASRYEPVFNDLMEQWALHYQTNMQATRAVRPKDKPSVEGSVHHAYQQIYARLRNEEFTSLSALTYRVRHLLDTANDRLMTDYGKSRRQRFIELEQEFLQPLPLTDFVYKRETTAKVKKNYHVILGEDRCQYSVPHEHIGKIVKLIYDESVVEVFLDFQRIALHQRIVGRRGIYRTVEEHMPESHRRYHQQQGWTEEDFTSKAAAVGPCTEEAVLRLLSSKAFAQQSFDACLGILRLQKKYGTTRLEAACSVALQVPRLNYRLVNNILENNRDKVSVAAGEQRASLLPLHDNIRGKEVYN
>NC_008639.1|WP_011745274.1|1633226_1633517_-|CRISPR-associated-endonuclease-Cas2
MLVLVTYDVNTETPAGRRRLRRIAKTCQNYGQRVQFSVFECNVDPSQWVKLRAKLMHEMDHAHDSLRFYFLGSNWQNRIEHEGAKEPRDLEGPLIL
>NC_008639.1|WP_011745275.1|1633520_1634552_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTTQGAYLSKEGECAVIKIDKVEKVRLPLHMLDGIICFGQITCSPFLMGHCAEKGVTVTFLTEYGKFLCQVQGPTKGNILLRRAQYRQADNYQQSAMLARAFVIGKIGNSRVTLARAMRDHPEKVDGEKMHYAQQLLAGCIKKLGDETDQERIRGIEGEAGRIYFEVFDQCITTSDPLFRFNGRNRRPPVDRVNCLLSFLYTLVTHDIRSALESCGLDPAAGFLHKDRPGRPSLALDMLEEFRSYIADRMALSLINRGQIQANDFTVSDTGAVLMKDDARKTLLTAYQKRKQEEIEHPYVREKMAVGLIWHMQAMLLARYIRGDIDMYPPFVWR
>NC_008639.1|WP_011745276.1|1634548_1635193_-|CRISPR-associated-protein-Cas4
MYDESDFIALSALQHFVYCPRQCALIHIEQVWAENSYTAEGREMHERVDDGETSYRPGVRTTRSVPLRSAMLGASGIADVVEWHKRNGREEPFPIEYKRGRQKKHDADKVQLCAQAICLEEMLGIAIPSGALFYGQTKRRFEVVFDAMLREKTAATAECVHELFRNGVTPLPEPGPKCNQCSLQELCLPEVVVHSRSAKNYVHKLLRELSEDEI
>NC_008639.1|WP_011745277.1|1635195_1636296_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTTVDKRYDFVLLFDVQDGNPNGDPDAGNFPRIDAETGIGLVTDVCLKRKVRNFVQINDVQQPGYDIYVKEKAVLGLAHFKAFKELGISTGEMSKKVINDQEMIEIFSDLTLPEGVSFAESDEHGVLSIAADADKNEIKDWMKAEKESLSKNVIKVISEALKEAKPRKPTAEETSRGKEKMCQDYYDIRTFGAVMSLKSAPNCGQVRGPIQMTFARSVEPIVALEHSITRMAVATEAEAEKQSGDNRTMGRKYTVPYGLYRAHGFVSANLAHQTGFSENDLDLFWNALLNMFDHDRSAARGLMSTRGLYVFEHSSVLGNAPASQLFERITVKRKEDSEGPARSFKEYDVLIDESSLGEVKLLRKLG
>NC_008639.1|WP_011745278.1|1636336_1638061_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MILHALYDYYQRKAADPESGIAPEGFEWKEIPFVIVIDQVGNFITFEDTREGDGKKKWAKKYLLPKSIHRPGSNSWMTSFLLWDHYGYVLGHARGESDKDQKMAHKQMPTFIKKIQALPSEVKEDEGVIAVIRFYENGGYEKVKSAHNWSECAKIVGCNLSFRIDGESDLVPCRDAVRKYVASQCSDNTDGVSGLCLITGENAAIARIHSDTPINKDSKKFVSFQKSSGYDSYGKEQAFNAPISKSAEFAYTTTMNMLLGKESKNKVQVGDATTVFWSQKQEAFEEVFPALFGYPKDDPDADVKAVRALYEGVNTGHANMDSDTRFYVLGLAPNSARISVRFWHTGTIAEFAGNIRQHFDDLAIIRSQKDSDHFSMFWLLSAMAHEGKVDNVPPNLSGQIFQSVITGGLYPATMLQQAIRRIRATQAKDLKNRSTQASILKAYLNRFSRIYKTKEKEINVALDPTNDNPGYRLGRLFAVLEKIQEEASPGINATIRDRFYGAASSTPVTVFPQLLKLKNHHLSKLKNVGRRVNFERILASIFDGIGNDMPSHLSMEDQARFAIGYYHQRQDFKK
>NC_008639.1|WP_011745279.1|1638057_1638771_-|type-I-C-CRISPR-associated-protein-Cas5
MEHWNKQFCLEVKGDYACFTRPEMKVERVSYDVITPSATRGIFEAIFWKPAIRWRIRKIEVLNPIKWISVRRNEVGQTASERSDCIFIEVARQQRAGLFLRDVAYRLHAELEFISPSERPDAKHPVPEALLDGWETEELRKDENPGKYYGIFERRARKGQCFNQPYLGCREFSCEFRLVDDLSNEPAPISETRNLGYMLYDLDFQKNVKEPPPAFFRVSMENGVINVPAWDSEEVRK
>NC_008639.1|WP_011745280.1|1638793_1640797_-|CRISPR-associated-helicase-Cas3'
MGRIDHSAAGAILATDKNKWIGRILGYLIAGHHTGLPDWHKEPGTKGDPLSERLSNPEHLMNALKGNPPENILNTALPSSLPCKSQDGGSELVHLWIRMLYSCLVDADFLDTERFMNPEKSELRPNEVDLVMLRERLDVYMAAKENGALDTPVNRARKEILRECRDKGRSLEPGLFSLTVPTGGGKTLASMAFALEHAIRHGKKRIIVAIPYTSIIEQTAAVYREVFGDDTVLEHHSNLDPARETAESRLATENWDAPIIVTTNVQLFESLFAARSSACRKLHNIVNSVVVLDETQMLPTDFLQPIVSVIKSLSTYFRASVVLCTATQPVLSGKVGTGKDILNGFEGGSVRELMSDPEKLFSVFQRVRVRMLGQAGERYEWTEIARQLQEHEQVLCIVNTRKDCRELHAQMPAGTVHLSALMCPEHRSKVISEVKSKLMTGELVRVVSTQLLEAGVDIDFPTVYRSFSGLDSIAQAAGRCNREGRLECGDVVVFNPPKPSPSGRLMKAENAAQELFRTDPELASSLMPEAFSRYFIRYFSGLNGFDTEQIMDLLAGNDALKYQIQFRTAAKRFKLIDDTLQHGIIVRYRDGKANIVALIDQLRFGGSNRKLMRQLQRYAVNVYDPDLKQLRGNGLIEEVNGVWVQTADSLYDPVFGLNIDATLNFVY
>NC_008639.1|WP_011745281.1|1640783_1641035_-|CRISPR-associated-endonuclease-Cas3''
MNKERKPVAHLRQNESDEWLEHELNDHLAGVATIATGFASEFGNADWAMAAGLLHDLGKYNPRWQDYIRKSNGDYLEDSDGQD

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Crispr_ID: NC_008639_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008639_3

1625359-1633049

TypeI

I-C

Consensus_repeat	Method
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	PILER-CR
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CRISPRCasFinder
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CRT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	PILER-CR
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CRISPRCasFinder

115 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3,cas3HD,WYL

The CRISPR arrays of NC_008639_3

>merge|NC_008639|3|1625359-1633049|PILER-CR,CRISPRCasFinder,CRT,PILER-CR,CRISPRCasFinder
GTTTCAATCCACGCGCCCGCAGGGGGCGCGACAGGCTATCCGTATCTGCGCTTTCACGTCTGTAAGCTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTGTCATTGATGGCCGATGATTTCCGTGAAATAGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAGGCCAAATCGACCACATCGACGGCGACGGTCTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTGATGTCGCGTTCCGGCACGACGCGCTCAAAAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTGCATCCACGGCAGTTCAGGGGAGGGATTCGGTTATGTTTCAATCCACGCTCCCGCAGGGGGCGCGACGGTGTCACTTACGGTTGTGTTTTTTGATCGGAATCGATTCAATCCACGCCGCCCGCCAGGGGGCGCTACCATTGAATACTACAAAGATGGAACCTCAACTACTCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCATGCTTGCCATTACCCTGATCGCAAGCCACCCAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAAAGGTGATTGTGATCACACACCTGCCAAGCATGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTCGGATTGTACTCTCTTGCCAAGTGGGTGATCGGCAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAGTTGTCCAGGCCTTGCACGACCTCAATCAACGGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTCGTGATCAAGGGTATGCAGGTGAGCGTAGACATCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGAAGCTCAGCGATGCGGAAACCGTAATCAACGAGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACACTTGATTTTCATTGGTCTTATGCCGGGCAAAACGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTTTTTATCCTTTGTCCGGAGCTTCATCGGTGTCAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTCAACAGCATCGCCCTGCTTGAAACCACCGAGCGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTCCTTGGTGCGGCGGACGCAGATGAACTGCTCAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAACACCCGATGGCTTATAGGCCTGTTTTTCAGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAGATATGTTTTATGCGGTATGGGACGGGTATATAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTTTAATGCTCCCGATGGAGTACGATCCAAAAAGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCGGACTGATGAAAAAGCACGTCTTAACATACCTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACATACTGAGCCTGTAGGGTTTTATCATCCTGTTTGAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCAAGGTAAGCCAGATAAGCCAGATCAGAACCGAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAATCAAGATAGAGTATTATGAGTACCTTTACGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTTCTTTCCATATTGCATGACGTGTCCAGTACTCGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCACTTGGCCGCAAGCTTGAGAATATCGCAGTTGTAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTTAACATAAATGTCAATTTTCGGACAACCAGTTTGTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTTTATCAACACCAATGTTTTTAATGTAGTTGCGTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACATTCGGCAAGCATTTCAGGTACAGCGCATGTATGAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCATTATCGTAATCCATTGTTGACAGCAAAGTGTTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCCGATCTTATCGGATCGTTTGCCACTTTGACAGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACATGGAATAGGTGCAAACAAAATGACACTTGGAAACGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTGTAAAGGAGATGTGCGACGCCATAAAATGGGCAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCAGCACAAGACGCTGCTCGGGTGTATGCTGCAGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTATTGATGTCGGGTTTTGGCACGACGAGTACACTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTACTGTTGTAATAGTGGCAGTGGTAATTTTTATGTTTCAATCCACGCGCCCGCAGGGGGCGCGACACACAATTGTGGGCGCCCGCCAAAAAACGATATAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAAGGCTCCGGTTGACAACCGCGCTGCTTAACGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGATTCCATACCGACTGGTGAAATCACTGGTATGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAAAAGCGACATAGAAGAGCGCATTTATGGAGACGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGCACTTGATCCAGAGCATGCAGCGCGAGTTGCCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTGTATACTCAGATAAGGCCGTCAGAAAGCCTAAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTGGCACCACATAGTACCTGCAGGAGACATGCGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAAAACAGATCAAGTGGGCAACTGACATCAAAGCCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGATTTTAACCTGGATTTCGACACCGCATTTCTCGAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTTGCTTTTGCGTATTTTTCTGCCGCCCAACGGTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTTTTGTCATTGCGGTTTGGTGTTGCGCACGCAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTACCGCAGGTCAGACTGTCACGATTGGCCTTGCAGTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTTAATTAGTGGATGAGACAATGACAACAAAACAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTGCCTTCAATATCAGGGTTCACGCCCTGTATCGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACATTTCCCCCTTGATAATCTCGCTCATCTGCCCGAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTATGAGCGTTTACGACATTAAAGCCGGAGGATGGAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGATTACCGCCATGTCGCTGACGTACCTCACCCTGTTTCAATCCACGCGCCTGCAGGGGGCGCGACCTTAACCATGAGGACGACGCTCTTGAGGGTATGGAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTGAATTTCAATGCTCCTGGATAAGATGTAAGAGTAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCATTGATCAAGAAGTGAAGCGCAAAAAGATAGACGTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTAATACTGGTATATTCGATGAGGCTGGTGAATACCTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACATGAGAATCTACCATCTGATCAAAGTCTACATCTCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACACAATTCTGCAGCAAAAGAAGCTCAAGCAAACAGAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGCCATATATCCAAAGGCTGCGGGTTTGTTGAGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTAGCCGGGAGCGATGATAATCTTGGCCGTGTAGCCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCACTCCGCGCAACTGTCCCGGCCTTGTCGGCCTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTCGGCATCAGCTCTGTCGAGTACACCATTGCCTCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTCGTTCACATCCTCGAGGATTGGCAGGACTGGACGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTGACGATTACGCTATCCACCAGCTTCGAGAGCGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCACCGAACATTACAAAGATGGAACCTCCACAACTCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAACCAACCAGACTGGGCAGACGTCCAGATGGTAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGACCTTTGGGATATGGGTTCACGATGGGCGACAATATGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCAGCCGGGGTATAGAGCTTTCAAGCAGCTTGCCTTGAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCAACCGGGATGTGCAGTCCGTGCGAGATCAGCTTAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTGATGCCGCACCGGTTCCCCTTCAAGTTCGACTGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCCCTCATAAGAAGATGCCGGGACGCCTTTTGTCTCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTTGGCTGGTGCAAGACGGAGGAAAGCTATGATACGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGGGATCGATGCCGATACTCCGTCTGTCGTAATGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTTTATGTCGTTGATCGTGTATAGCCCGACGATAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCATGCAGACCACCTGCGCTGACGAGCAGGAAGCAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGACGGCTTTACGGTAGATCGGGCAAATGATGCGGTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGCATGTGTCGAACAGATCACCATCGAAGAGAACCGTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCGGCAGAGGGCTGAGTTGCAAGAGCGCCTTGATGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGATAACAAAATTACCTGCAAGCACAAAAAAAAGCAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAGAGGCGCCCCGGCGGAACGTGCTGAGTTTTACCAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGGAGGACATCTTCATCAATTCTTCATCTGTGATTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTCAAAAAAATTCATTAAAAAGTATTGTGATTGCAGGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGGCCAATGCAGCCGGGAACCGTAACCCCGGATCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACATGGCAAAGCCTGAAAAAATATTCATGCGCTTTGAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTTTGCCGAAGGTGCCACAAAATCAAGCATCGCGGGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTGCAAGGAAGTCTTCCAAATTCCCTTTGTGTCGAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAGCTGATGAACGACGAGCTATCAATTAAAAAACAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAGAAGAGCAAAGCTTGCCGTTAATCCATTGTGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACATTACCCGAATGGCCAACCATCCGAGTATCGCGAAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTGGATCAATATGGTCAGATTCCAGGATTGCGGAATGTTTCAATCCACGCGCCCGCAGGGGGCGCGACATAGTGAATTTTGTGAAAATCACATATAGGAGATGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTGGTACTTACTCCTTTTATGGGCGTAGGATCGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTGCGGGAGCAGCTTGATGGCGGTGACGTTTTCGACGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTTCTGTCGCCGGCGGCGCTCAGGTGCTGCAGATGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGGATATTTGACTGACGTTAATGTGATCGATGGCGTTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAAGCGGAGTCGAGGATATGACAATCTCAGCCATTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAACTACGATCTTGGGGCGGAGGTTGTTCGGAGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTCCGGATTCGACGTTTGTCGGGTAGCTTCCGGCGGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTCTCGCGGAGTTGTACATCTCGACCAACAAGGTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTCATACCATTGTGTGTTGATATGATGCGCAGAGGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAAGAAGGTTTATTATAAGCCTTTTGCGCCTCATGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACTAACTTTAGCATGGTACCATCTGTAAGTGTACCGAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCGAATTTGCGACAATGTCGCGAAACCCTGGAGTCGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCCAACAATTGTTCCCGTTGCTGAATCAGTAACGGTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGTTATCCGCAAAAACAAATTCGCAATCCTCAACAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACATCTGCGCTTTTACATCAGCAAGCTGCACAGGATGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCCCTCTATCTTTGATCGGTTTTGCTCAAGAGACGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTCACGACATCGGGGTGCGGGAACTGATGAGCGGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACAGCCATACGGACACAGCCGCGCAACATTCCGTTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCGTTTCTCGATCAAGTGATCGGCGATATACGGCAGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCGATGGCGCAGGCCAAAACCGTTGAGGCTCAAGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGACGCATGGTCGAGAAAGAGTTGCCTGAATCGGCACCTGTGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCAATGCTTCTGTTAAGTTGAGCAAGCGCAATCACTGGTTTCAATCCACGCGCCCGCAGGGGGCGCGACCACAGCCCGCCCTTATCAGCAGGCGTTGTTCGAGGCGTTTCAATCCACGCGCCCGCAGGGGGCGCGAC

>NC_008639|3|2|1625359-1625656|PILER-CR
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGGCTATCCGTATCTGCGCTTTCACGTCTGTAAGCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGTCATTGATGGCCGATGATTTCCGTGAAATAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGGCCAAATCGACCACATCGACGGCGACGGTCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGATGTCGCGTTCCGGCACGACGCGCTCAAAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTGCATCCACGGCAGTTCAGGGGAGGGATTCGGTTATGTTTCAATCCACGCTCCCGCAGGGGGCGCGACGGTGTCACTTACGGTTGTGTTTTTTGATCGGAATCGATTCAATCCACGCCGCCCGCCAGGGGGCGCTACCATTGAATACTACAAAGATGGAACCTCAACTACTCGTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATGCTTGCCATTACCCTGATCGCAAGCCACCCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAGGTGATTGTGATCACACACCTGCCAAGCAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCGGATTGTACTCTCTTGCCAAGTGGGTGATCGGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGTTGTCCAGGCCTTGCACGACCTCAATCAACGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCGTGATCAAGGGTATGCAGGTGAGCGTAGACATC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GAAGCTCAGCGATGCGGAAACCGTAATCAACGAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACTTGATTTTCATTGGTCTTATGCCGGGCAAAAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTTTTATCCTTTGTCCGGAGCTTCATCGGTGTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCAACAGCATCGCCCTGCTTGAAACCACCGAGCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTCCTTGGTGCGGCGGACGCAGATGAACTGCTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AACACCCGATGGCTTATAGGCCTGTTTTTCAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGATATGTTTTATGCGGTATGGGACGGGTATATA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTAATGCTCCCGATGGAGTACGATCCAAAAAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGGACTGATGAAAAAGCACGTCTTAACATACCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATACTGAGCCTGTAGGGTTTTATCATCCTGTTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAAGGTAAGCCAGATAAGCCAGATCAGAACCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAATCAAGATAGAGTATTATGAGTACCTTTACGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTCTTTCCATATTGCATGACGTGTCCAGTACTCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACTTGGCCGCAAGCTTGAGAATATCGCAGTTGTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTAACATAAATGTCAATTTTCGGACAACCAGTTTGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTATCAACACCAATGTTTTTAATGTAGTTGCGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTCGGCAAGCATTTCAGGTACAGCGCATGTATGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATTATCGTAATCCATTGTTGACAGCAAAGTGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCGATCTTATCGGATCGTTTGCCACTTTGACAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGGAATAGGTGCAAACAAAATGACACTTGGAAACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGTAAAGGAGATGTGCGACGCCATAAAATGGGCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAGCACAAGACGCTGCTCGGGTGTATGCTGCAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TATTGATGTCGGGTTTTGGCACGACGAGTACACT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTACTGTTGTAATAGTGGCAGTGGTAATTTTTAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACACAATTGTGGGCGCCCGCCAAAAAACGATATA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAGGCTCCGGTTGACAACCGCGCTGCTTAACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTCCATACCGACTGGTGAAATCACTGGTATG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAAGCGACATAGAAGAGCGCATTTATGGAGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCACTTGATCCAGAGCATGCAGCGCGAGTTGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGTATACTCAGATAAGGCCGTCAGAAAGCCTAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGCACCACATAGTACCTGCAGGAGACATGCGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAACAGATCAAGTGGGCAACTGACATCAAAGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTTTAACCTGGATTTCGACACCGCATTTCTCGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTGCTTTTGCGTATTTTTCTGCCGCCCAACGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTTTTGTCATTGCGGTTTGGTGTTGCGCACGCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TACCGCAGGTCAGACTGTCACGATTGGCCTTGCAGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTAATTAGTGGATGAGACAATGACAACAAAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGCCTTCAATATCAGGGTTCACGCCCTGTATCGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTTCCCCCTTGATAATCTCGCTCATCTGCCCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TATGAGCGTTTACGACATTAAAGCCGGAGGATGGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTACCGCCATGTCGCTGACGTACCTCACCCT
GTTTCAATCCACGCGCCTGCAGGGGGCGCGAC	CTTAACCATGAGGACGACGCTCTTGAGGGTATGGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGAATTTCAATGCTCCTGGATAAGATGTAAGAGTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATTGATCAAGAAGTGAAGCGCAAAAAGATAGACGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TAATACTGGTATATTCGATGAGGCTGGTGAATACCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGAGAATCTACCATCTGATCAAAGTCTACATCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACAATTCTGCAGCAAAAGAAGCTCAAGCAAACAGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCCATATATCCAAAGGCTGCGGGTTTGTTGAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTAGCCGGGAGCGATGATAATCTTGGCCGTGTAGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACTCCGCGCAACTGTCCCGGCCTTGTCGGCCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCGGCATCAGCTCTGTCGAGTACACCATTGCCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTCGTTCACATCCTCGAGGATTGGCAGGACTGGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGACGATTACGCTATCCACCAGCTTCGAGAGCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACCGAACATTACAAAGATGGAACCTCCACAACTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AACCAACCAGACTGGGCAGACGTCCAGATGGTAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GACCTTTGGGATATGGGTTCACGATGGGCGACAATAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAGCCGGGGTATAGAGCTTTCAAGCAGCTTGCCTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAACCGGGATGTGCAGTCCGTGCGAGATCAGCTTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGATGCCGCACCGGTTCCCCTTCAAGTTCGACTG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCCTCATAAGAAGATGCCGGGACGCCTTTTGTCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTGGCTGGTGCAAGACGGAGGAAAGCTATGATAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGGATCGATGCCGATACTCCGTCTGTCGTAATG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTATGTCGTTGATCGTGTATAGCCCGACGATAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATGCAGACCACCTGCGCTGACGAGCAGGAAGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GACGGCTTTACGGTAGATCGGGCAAATGATGCGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCATGTGTCGAACAGATCACCATCGAAGAGAACCGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGGCAGAGGGCTGAGTTGCAAGAGCGCCTTGATGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATAACAAAATTACCTGCAAGCACAAAAAAAAGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGAGGCGCCCCGGCGGAACGTGCTGAGTTTTACCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGAGGACATCTTCATCAATTCTTCATCTGTGATT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCAAAAAAATTCATTAAAAAGTATTGTGATTGCAGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCCAATGCAGCCGGGAACCGTAACCCCGGATC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGGCAAAGCCTGAAAAAATATTCATGCGCTTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTTTGCCGAAGGTGCCACAAAATCAAGCATCGCGGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGCAAGGAAGTCTTCCAAATTCCCTTTGTGTCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGCTGATGAACGACGAGCTATCAATTAAAAAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGAAGAGCAAAGCTTGCCGTTAATCCATTGTGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTACCCGAATGGCCAACCATCCGAGTATCGCGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGATCAATATGGTCAGATTCCAGGATTGCGGAAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATAGTGAATTTTGTGAAAATCACATATAGGAGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGTACTTACTCCTTTTATGGGCGTAGGATCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGCGGGAGCAGCTTGATGGCGGTGACGTTTTCGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCTGTCGCCGGCGGCGCTCAGGTGCTGCAGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGATATTTGACTGACGTTAATGTGATCGATGGCGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAGCGGAGTCGAGGATATGACAATCTCAGCCATT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAACTACGATCTTGGGGCGGAGGTTGTTCGGAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCCGGATTCGACGTTTGTCGGGTAGCTTCCGGCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCTCGCGGAGTTGTACATCTCGACCAACAAGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCATACCATTGTGTGTTGATATGATGCGCAGAGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGAAGGTTTATTATAAGCCTTTTGCGCCTCATGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TAACTTTAGCATGGTACCATCTGTAAGTGTACCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGAATTTGCGACAATGTCGCGAAACCCTGGAGTCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCAACAATTGTTCCCGTTGCTGAATCAGTAACGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTATCCGCAAAAACAAATTCGCAATCCTCAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATCTGCGCTTTTACATCAGCAAGCTGCACAGGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCCTCTATCTTTGATCGGTTTTGCTCAAGAGACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCACGACATCGGGGTGCGGGAACTGATGAGCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGCCATACGGACACAGCCGCGCAACATTCCGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGTTTCTCGATCAAGTGATCGGCGATATACGGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGATGGCGCAGGCCAAAACCGTTGAGGCTCAAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCATGGTCGAGAAAGAGTTGCCTGAATCGGCACCTGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAATGCTTCTGTTAAGTTGAGCAAGCGCAATCACTG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACAGCCCGCCCTTATCAGCAGGCGTTGTTCGAGGC


>NC_008639|3|3|1625359-1625726|CRISPRCasFinder
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGGCTATCCGTATCTGCGCTTTCACGTCTGTAAGCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGTCATTGATGGCCGATGATTTCCGTGAAATAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGGCCAAATCGACCACATCGACGGCGACGGTCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGATGTCGCGTTCCGGCACGACGCGCTCAAAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGCATCCACGGCAGTTCAGGGGAGGGATTCGGTTAT
GTTTCAATCCACGCTCCCGCAGGGGGCGCGACGGTGTCACTTACGGTTGTGTTTTTTGATCGGAATCGATTCAATCCACGCCGCCCGCCAGGGGGCGCTACCATTGAATACTACAAAGATGGAACCTCAACTACTCGTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATGCTTGCCATTACCCTGATCGCAAGCCACCCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAGGTGATTGTGATCACACACCTGCCAAGCAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCGGATTGTACTCTCTTGCCAAGTGGGTGATCGGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGTTGTCCAGGCCTTGCACGACCTCAATCAACGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCGTGATCAAGGGTATGCAGGTGAGCGTAGACATC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GAAGCTCAGCGATGCGGAAACCGTAATCAACGAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACTTGATTTTCATTGGTCTTATGCCGGGCAAAAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTTTTATCCTTTGTCCGGAGCTTCATCGGTGTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCAACAGCATCGCCCTGCTTGAAACCACCGAGCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTCCTTGGTGCGGCGGACGCAGATGAACTGCTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AACACCCGATGGCTTATAGGCCTGTTTTTCAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGATATGTTTTATGCGGTATGGGACGGGTATATA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTAATGCTCCCGATGGAGTACGATCCAAAAAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGGACTGATGAAAAAGCACGTCTTAACATACCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATACTGAGCCTGTAGGGTTTTATCATCCTGTTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAAGGTAAGCCAGATAAGCCAGATCAGAACCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAATCAAGATAGAGTATTATGAGTACCTTTACGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTCTTTCCATATTGCATGACGTGTCCAGTACTCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACTTGGCCGCAAGCTTGAGAATATCGCAGTTGTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTAACATAAATGTCAATTTTCGGACAACCAGTTTGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTATCAACACCAATGTTTTTAATGTAGTTGCGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTCGGCAAGCATTTCAGGTACAGCGCATGTATGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATTATCGTAATCCATTGTTGACAGCAAAGTGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCGATCTTATCGGATCGTTTGCCACTTTGACAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGGAATAGGTGCAAACAAAATGACACTTGGAAACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGTAAAGGAGATGTGCGACGCCATAAAATGGGCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAGCACAAGACGCTGCTCGGGTGTATGCTGCAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TATTGATGTCGGGTTTTGGCACGACGAGTACACT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTACTGTTGTAATAGTGGCAGTGGTAATTTTTAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACACAATTGTGGGCGCCCGCCAAAAAACGATATA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAGGCTCCGGTTGACAACCGCGCTGCTTAACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTCCATACCGACTGGTGAAATCACTGGTATG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAAGCGACATAGAAGAGCGCATTTATGGAGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCACTTGATCCAGAGCATGCAGCGCGAGTTGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGTATACTCAGATAAGGCCGTCAGAAAGCCTAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGCACCACATAGTACCTGCAGGAGACATGCGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAACAGATCAAGTGGGCAACTGACATCAAAGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTTTAACCTGGATTTCGACACCGCATTTCTCGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTGCTTTTGCGTATTTTTCTGCCGCCCAACGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTTTTGTCATTGCGGTTTGGTGTTGCGCACGCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TACCGCAGGTCAGACTGTCACGATTGGCCTTGCAGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTAATTAGTGGATGAGACAATGACAACAAAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGCCTTCAATATCAGGGTTCACGCCCTGTATCGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTTCCCCCTTGATAATCTCGCTCATCTGCCCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TATGAGCGTTTACGACATTAAAGCCGGAGGATGGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTACCGCCATGTCGCTGACGTACCTCACCCT
GTTTCAATCCACGCGCCTGCAGGGGGCGCGAC	CTTAACCATGAGGACGACGCTCTTGAGGGTATGGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGAATTTCAATGCTCCTGGATAAGATGTAAGAGTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATTGATCAAGAAGTGAAGCGCAAAAAGATAGACGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TAATACTGGTATATTCGATGAGGCTGGTGAATACCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGAGAATCTACCATCTGATCAAAGTCTACATCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACAATTCTGCAGCAAAAGAAGCTCAAGCAAACAGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCCATATATCCAAAGGCTGCGGGTTTGTTGAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTAGCCGGGAGCGATGATAATCTTGGCCGTGTAGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACTCCGCGCAACTGTCCCGGCCTTGTCGGCCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCGGCATCAGCTCTGTCGAGTACACCATTGCCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTCGTTCACATCCTCGAGGATTGGCAGGACTGGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGACGATTACGCTATCCACCAGCTTCGAGAGCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACCGAACATTACAAAGATGGAACCTCCACAACTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AACCAACCAGACTGGGCAGACGTCCAGATGGTAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GACCTTTGGGATATGGGTTCACGATGGGCGACAATAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAGCCGGGGTATAGAGCTTTCAAGCAGCTTGCCTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAACCGGGATGTGCAGTCCGTGCGAGATCAGCTTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGATGCCGCACCGGTTCCCCTTCAAGTTCGACTG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCCTCATAAGAAGATGCCGGGACGCCTTTTGTCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTGGCTGGTGCAAGACGGAGGAAAGCTATGATAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGGATCGATGCCGATACTCCGTCTGTCGTAATG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTATGTCGTTGATCGTGTATAGCCCGACGATAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATGCAGACCACCTGCGCTGACGAGCAGGAAGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GACGGCTTTACGGTAGATCGGGCAAATGATGCGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCATGTGTCGAACAGATCACCATCGAAGAGAACCGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGGCAGAGGGCTGAGTTGCAAGAGCGCCTTGATGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATAACAAAATTACCTGCAAGCACAAAAAAAAGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGAGGCGCCCCGGCGGAACGTGCTGAGTTTTACCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGAGGACATCTTCATCAATTCTTCATCTGTGATT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCAAAAAAATTCATTAAAAAGTATTGTGATTGCAGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCCAATGCAGCCGGGAACCGTAACCCCGGATC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGGCAAAGCCTGAAAAAATATTCATGCGCTTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTTTGCCGAAGGTGCCACAAAATCAAGCATCGCGGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGCAAGGAAGTCTTCCAAATTCCCTTTGTGTCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGCTGATGAACGACGAGCTATCAATTAAAAAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGAAGAGCAAAGCTTGCCGTTAATCCATTGTGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTACCCGAATGGCCAACCATCCGAGTATCGCGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGATCAATATGGTCAGATTCCAGGATTGCGGAAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATAGTGAATTTTGTGAAAATCACATATAGGAGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGTACTTACTCCTTTTATGGGCGTAGGATCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGCGGGAGCAGCTTGATGGCGGTGACGTTTTCGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCTGTCGCCGGCGGCGCTCAGGTGCTGCAGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGATATTTGACTGACGTTAATGTGATCGATGGCGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAGCGGAGTCGAGGATATGACAATCTCAGCCATT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAACTACGATCTTGGGGCGGAGGTTGTTCGGAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCCGGATTCGACGTTTGTCGGGTAGCTTCCGGCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCTCGCGGAGTTGTACATCTCGACCAACAAGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCATACCATTGTGTGTTGATATGATGCGCAGAGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGAAGGTTTATTATAAGCCTTTTGCGCCTCATGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TAACTTTAGCATGGTACCATCTGTAAGTGTACCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGAATTTGCGACAATGTCGCGAAACCCTGGAGTCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCAACAATTGTTCCCGTTGCTGAATCAGTAACGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTATCCGCAAAAACAAATTCGCAATCCTCAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATCTGCGCTTTTACATCAGCAAGCTGCACAGGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCCTCTATCTTTGATCGGTTTTGCTCAAGAGACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCACGACATCGGGGTGCGGGAACTGATGAGCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGCCATACGGACACAGCCGCGCAACATTCCGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGTTTCTCGATCAAGTGATCGGCGATATACGGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGATGGCGCAGGCCAAAACCGTTGAGGCTCAAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCATGGTCGAGAAAGAGTTGCCTGAATCGGCACCTGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAATGCTTCTGTTAAGTTGAGCAAGCGCAATCACTG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACAGCCCGCCCTTATCAGCAGGCGTTGTTCGAGGC


>NC_008639|3|2|1625359-1633049|CRT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGGCTATCCGTATCTGCGCTTTCACGTCTGTAAGCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGTCATTGATGGCCGATGATTTCCGTGAAATAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGGCCAAATCGACCACATCGACGGCGACGGTCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGATGTCGCGTTCCGGCACGACGCGCTCAAAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGCATCCACGGCAGTTCAGGGGAGGGATTCGGTTAT
GTTTCAATCCACGCTCCCGCAGGGGGCGCGAC	GGTGTCACTTACGGTTGTGTTTTTTGATCGGAATC
GATTCAATCCACGCCGCCCGCCAGGGGGCGCT	ACCATTGAATACTACAAAGATGGAACCTCAACTACTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATGCTTGCCATTACCCTGATCGCAAGCCACCCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAGGTGATTGTGATCACACACCTGCCAAGCAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCGGATTGTACTCTCTTGCCAAGTGGGTGATCGGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGTTGTCCAGGCCTTGCACGACCTCAATCAACGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCGTGATCAAGGGTATGCAGGTGAGCGTAGACATC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GAAGCTCAGCGATGCGGAAACCGTAATCAACGAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACTTGATTTTCATTGGTCTTATGCCGGGCAAAAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTTTTATCCTTTGTCCGGAGCTTCATCGGTGTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCAACAGCATCGCCCTGCTTGAAACCACCGAGCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTCCTTGGTGCGGCGGACGCAGATGAACTGCTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AACACCCGATGGCTTATAGGCCTGTTTTTCAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGATATGTTTTATGCGGTATGGGACGGGTATATA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTAATGCTCCCGATGGAGTACGATCCAAAAAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGGACTGATGAAAAAGCACGTCTTAACATACCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATACTGAGCCTGTAGGGTTTTATCATCCTGTTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAAGGTAAGCCAGATAAGCCAGATCAGAACCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAATCAAGATAGAGTATTATGAGTACCTTTACGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTCTTTCCATATTGCATGACGTGTCCAGTACTCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACTTGGCCGCAAGCTTGAGAATATCGCAGTTGTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTAACATAAATGTCAATTTTCGGACAACCAGTTTGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTATCAACACCAATGTTTTTAATGTAGTTGCGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTCGGCAAGCATTTCAGGTACAGCGCATGTATGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATTATCGTAATCCATTGTTGACAGCAAAGTGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCGATCTTATCGGATCGTTTGCCACTTTGACAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGGAATAGGTGCAAACAAAATGACACTTGGAAACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGTAAAGGAGATGTGCGACGCCATAAAATGGGCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAGCACAAGACGCTGCTCGGGTGTATGCTGCAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TATTGATGTCGGGTTTTGGCACGACGAGTACACT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTACTGTTGTAATAGTGGCAGTGGTAATTTTTAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACACAATTGTGGGCGCCCGCCAAAAAACGATATA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAGGCTCCGGTTGACAACCGCGCTGCTTAACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTCCATACCGACTGGTGAAATCACTGGTATG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAAGCGACATAGAAGAGCGCATTTATGGAGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCACTTGATCCAGAGCATGCAGCGCGAGTTGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGTATACTCAGATAAGGCCGTCAGAAAGCCTAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGCACCACATAGTACCTGCAGGAGACATGCGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAACAGATCAAGTGGGCAACTGACATCAAAGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTTTAACCTGGATTTCGACACCGCATTTCTCGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTGCTTTTGCGTATTTTTCTGCCGCCCAACGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTTTTGTCATTGCGGTTTGGTGTTGCGCACGCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TACCGCAGGTCAGACTGTCACGATTGGCCTTGCAGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTAATTAGTGGATGAGACAATGACAACAAAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGCCTTCAATATCAGGGTTCACGCCCTGTATCGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTTCCCCCTTGATAATCTCGCTCATCTGCCCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TATGAGCGTTTACGACATTAAAGCCGGAGGATGGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTACCGCCATGTCGCTGACGTACCTCACCCT
GTTTCAATCCACGCGCCTGCAGGGGGCGCGAC	CTTAACCATGAGGACGACGCTCTTGAGGGTATGGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGAATTTCAATGCTCCTGGATAAGATGTAAGAGTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATTGATCAAGAAGTGAAGCGCAAAAAGATAGACGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TAATACTGGTATATTCGATGAGGCTGGTGAATACCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGAGAATCTACCATCTGATCAAAGTCTACATCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACAATTCTGCAGCAAAAGAAGCTCAAGCAAACAGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCCATATATCCAAAGGCTGCGGGTTTGTTGAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTAGCCGGGAGCGATGATAATCTTGGCCGTGTAGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACTCCGCGCAACTGTCCCGGCCTTGTCGGCCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCGGCATCAGCTCTGTCGAGTACACCATTGCCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTCGTTCACATCCTCGAGGATTGGCAGGACTGGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGACGATTACGCTATCCACCAGCTTCGAGAGCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACCGAACATTACAAAGATGGAACCTCCACAACTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AACCAACCAGACTGGGCAGACGTCCAGATGGTAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GACCTTTGGGATATGGGTTCACGATGGGCGACAATAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAGCCGGGGTATAGAGCTTTCAAGCAGCTTGCCTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAACCGGGATGTGCAGTCCGTGCGAGATCAGCTTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGATGCCGCACCGGTTCCCCTTCAAGTTCGACTG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCCTCATAAGAAGATGCCGGGACGCCTTTTGTCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTGGCTGGTGCAAGACGGAGGAAAGCTATGATAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGGATCGATGCCGATACTCCGTCTGTCGTAATG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTATGTCGTTGATCGTGTATAGCCCGACGATAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATGCAGACCACCTGCGCTGACGAGCAGGAAGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GACGGCTTTACGGTAGATCGGGCAAATGATGCGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCATGTGTCGAACAGATCACCATCGAAGAGAACCGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGGCAGAGGGCTGAGTTGCAAGAGCGCCTTGATGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATAACAAAATTACCTGCAAGCACAAAAAAAAGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGAGGCGCCCCGGCGGAACGTGCTGAGTTTTACCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGAGGACATCTTCATCAATTCTTCATCTGTGATT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCAAAAAAATTCATTAAAAAGTATTGTGATTGCAGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCCAATGCAGCCGGGAACCGTAACCCCGGATC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGGCAAAGCCTGAAAAAATATTCATGCGCTTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTTTGCCGAAGGTGCCACAAAATCAAGCATCGCGGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGCAAGGAAGTCTTCCAAATTCCCTTTGTGTCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGCTGATGAACGACGAGCTATCAATTAAAAAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGAAGAGCAAAGCTTGCCGTTAATCCATTGTGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTACCCGAATGGCCAACCATCCGAGTATCGCGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGATCAATATGGTCAGATTCCAGGATTGCGGAAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATAGTGAATTTTGTGAAAATCACATATAGGAGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGTACTTACTCCTTTTATGGGCGTAGGATCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGCGGGAGCAGCTTGATGGCGGTGACGTTTTCGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCTGTCGCCGGCGGCGCTCAGGTGCTGCAGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGATATTTGACTGACGTTAATGTGATCGATGGCGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAGCGGAGTCGAGGATATGACAATCTCAGCCATT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAACTACGATCTTGGGGCGGAGGTTGTTCGGAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCCGGATTCGACGTTTGTCGGGTAGCTTCCGGCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCTCGCGGAGTTGTACATCTCGACCAACAAGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCATACCATTGTGTGTTGATATGATGCGCAGAGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGAAGGTTTATTATAAGCCTTTTGCGCCTCATGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TAACTTTAGCATGGTACCATCTGTAAGTGTACCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGAATTTGCGACAATGTCGCGAAACCCTGGAGTCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCAACAATTGTTCCCGTTGCTGAATCAGTAACGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTATCCGCAAAAACAAATTCGCAATCCTCAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATCTGCGCTTTTACATCAGCAAGCTGCACAGGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCCTCTATCTTTGATCGGTTTTGCTCAAGAGACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCACGACATCGGGGTGCGGGAACTGATGAGCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGCCATACGGACACAGCCGCGCAACATTCCGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGTTTCTCGATCAAGTGATCGGCGATATACGGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGATGGCGCAGGCCAAAACCGTTGAGGCTCAAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCATGGTCGAGAAAGAGTTGCCTGAATCGGCACCTGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAATGCTTCTGTTAAGTTGAGCAAGCGCAATCACTG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACAGCCCGCCCTTATCAGCAGGCGTTGTTCGAGGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC

>NC_008639|3|3|1625830-1633049|PILER-CR
	AGGCTATCCGTATCTGCGCTTTCACGTCTGTAAGCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGTCATTGATGGCCGATGATTTCCGTGAAATAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGGCCAAATCGACCACATCGACGGCGACGGTCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGATGTCGCGTTCCGGCACGACGCGCTCAAAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGACCTGCATCCACGGCAGTTCAGGGGAGGGATTCGGTTATGTTTCAATCCACGCTCCCGCAGGGGGCGCGACGGTGTCACTTACGGTTGTGTTTTTTGATCGGAATCGATTCAATCCACGCCGCCCGCCAGGGGGCGCTACCATTGAATACTACAAAGATGGAACCTCAACTACTCGTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATGCTTGCCATTACCCTGATCGCAAGCCACCCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAGGTGATTGTGATCACACACCTGCCAAGCAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCGGATTGTACTCTCTTGCCAAGTGGGTGATCGGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGTTGTCCAGGCCTTGCACGACCTCAATCAACGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCGTGATCAAGGGTATGCAGGTGAGCGTAGACATC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GAAGCTCAGCGATGCGGAAACCGTAATCAACGAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACTTGATTTTCATTGGTCTTATGCCGGGCAAAAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTTTTATCCTTTGTCCGGAGCTTCATCGGTGTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCAACAGCATCGCCCTGCTTGAAACCACCGAGCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTCCTTGGTGCGGCGGACGCAGATGAACTGCTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AACACCCGATGGCTTATAGGCCTGTTTTTCAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGATATGTTTTATGCGGTATGGGACGGGTATATA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTAATGCTCCCGATGGAGTACGATCCAAAAAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGGACTGATGAAAAAGCACGTCTTAACATACCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATACTGAGCCTGTAGGGTTTTATCATCCTGTTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAAGGTAAGCCAGATAAGCCAGATCAGAACCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAATCAAGATAGAGTATTATGAGTACCTTTACGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTCTTTCCATATTGCATGACGTGTCCAGTACTCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACTTGGCCGCAAGCTTGAGAATATCGCAGTTGTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTAACATAAATGTCAATTTTCGGACAACCAGTTTGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTATCAACACCAATGTTTTTAATGTAGTTGCGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTCGGCAAGCATTTCAGGTACAGCGCATGTATGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATTATCGTAATCCATTGTTGACAGCAAAGTGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCGATCTTATCGGATCGTTTGCCACTTTGACAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGGAATAGGTGCAAACAAAATGACACTTGGAAACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGTAAAGGAGATGTGCGACGCCATAAAATGGGCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAGCACAAGACGCTGCTCGGGTGTATGCTGCAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TATTGATGTCGGGTTTTGGCACGACGAGTACACT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTACTGTTGTAATAGTGGCAGTGGTAATTTTTAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACACAATTGTGGGCGCCCGCCAAAAAACGATATA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAGGCTCCGGTTGACAACCGCGCTGCTTAACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTCCATACCGACTGGTGAAATCACTGGTATG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAAGCGACATAGAAGAGCGCATTTATGGAGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCACTTGATCCAGAGCATGCAGCGCGAGTTGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGTATACTCAGATAAGGCCGTCAGAAAGCCTAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGCACCACATAGTACCTGCAGGAGACATGCGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAACAGATCAAGTGGGCAACTGACATCAAAGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTTTAACCTGGATTTCGACACCGCATTTCTCGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTGCTTTTGCGTATTTTTCTGCCGCCCAACGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTTTTGTCATTGCGGTTTGGTGTTGCGCACGCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TACCGCAGGTCAGACTGTCACGATTGGCCTTGCAGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTAATTAGTGGATGAGACAATGACAACAAAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGCCTTCAATATCAGGGTTCACGCCCTGTATCGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTTCCCCCTTGATAATCTCGCTCATCTGCCCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TATGAGCGTTTACGACATTAAAGCCGGAGGATGGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTACCGCCATGTCGCTGACGTACCTCACCCT
GTTTCAATCCACGCGCCTGCAGGGGGCGCGAC	CTTAACCATGAGGACGACGCTCTTGAGGGTATGGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGAATTTCAATGCTCCTGGATAAGATGTAAGAGTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATTGATCAAGAAGTGAAGCGCAAAAAGATAGACGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TAATACTGGTATATTCGATGAGGCTGGTGAATACCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGAGAATCTACCATCTGATCAAAGTCTACATCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACAATTCTGCAGCAAAAGAAGCTCAAGCAAACAGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCCATATATCCAAAGGCTGCGGGTTTGTTGAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTAGCCGGGAGCGATGATAATCTTGGCCGTGTAGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACTCCGCGCAACTGTCCCGGCCTTGTCGGCCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCGGCATCAGCTCTGTCGAGTACACCATTGCCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTCGTTCACATCCTCGAGGATTGGCAGGACTGGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGACGATTACGCTATCCACCAGCTTCGAGAGCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACCGAACATTACAAAGATGGAACCTCCACAACTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AACCAACCAGACTGGGCAGACGTCCAGATGGTAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GACCTTTGGGATATGGGTTCACGATGGGCGACAATAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAGCCGGGGTATAGAGCTTTCAAGCAGCTTGCCTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAACCGGGATGTGCAGTCCGTGCGAGATCAGCTTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGATGCCGCACCGGTTCCCCTTCAAGTTCGACTG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCCTCATAAGAAGATGCCGGGACGCCTTTTGTCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTGGCTGGTGCAAGACGGAGGAAAGCTATGATAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGGATCGATGCCGATACTCCGTCTGTCGTAATG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTATGTCGTTGATCGTGTATAGCCCGACGATAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATGCAGACCACCTGCGCTGACGAGCAGGAAGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GACGGCTTTACGGTAGATCGGGCAAATGATGCGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCATGTGTCGAACAGATCACCATCGAAGAGAACCGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGGCAGAGGGCTGAGTTGCAAGAGCGCCTTGATGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATAACAAAATTACCTGCAAGCACAAAAAAAAGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGAGGCGCCCCGGCGGAACGTGCTGAGTTTTACCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGAGGACATCTTCATCAATTCTTCATCTGTGATT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCAAAAAAATTCATTAAAAAGTATTGTGATTGCAGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCCAATGCAGCCGGGAACCGTAACCCCGGATC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGGCAAAGCCTGAAAAAATATTCATGCGCTTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTTTGCCGAAGGTGCCACAAAATCAAGCATCGCGGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGCAAGGAAGTCTTCCAAATTCCCTTTGTGTCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGCTGATGAACGACGAGCTATCAATTAAAAAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGAAGAGCAAAGCTTGCCGTTAATCCATTGTGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTACCCGAATGGCCAACCATCCGAGTATCGCGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGATCAATATGGTCAGATTCCAGGATTGCGGAAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATAGTGAATTTTGTGAAAATCACATATAGGAGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGTACTTACTCCTTTTATGGGCGTAGGATCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGCGGGAGCAGCTTGATGGCGGTGACGTTTTCGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCTGTCGCCGGCGGCGCTCAGGTGCTGCAGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGATATTTGACTGACGTTAATGTGATCGATGGCGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAGCGGAGTCGAGGATATGACAATCTCAGCCATT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAACTACGATCTTGGGGCGGAGGTTGTTCGGAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCCGGATTCGACGTTTGTCGGGTAGCTTCCGGCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCTCGCGGAGTTGTACATCTCGACCAACAAGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCATACCATTGTGTGTTGATATGATGCGCAGAGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGAAGGTTTATTATAAGCCTTTTGCGCCTCATGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TAACTTTAGCATGGTACCATCTGTAAGTGTACCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGAATTTGCGACAATGTCGCGAAACCCTGGAGTCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCAACAATTGTTCCCGTTGCTGAATCAGTAACGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTATCCGCAAAAACAAATTCGCAATCCTCAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATCTGCGCTTTTACATCAGCAAGCTGCACAGGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCCTCTATCTTTGATCGGTTTTGCTCAAGAGACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCACGACATCGGGGTGCGGGAACTGATGAGCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGCCATACGGACACAGCCGCGCAACATTCCGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGTTTCTCGATCAAGTGATCGGCGATATACGGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGATGGCGCAGGCCAAAACCGTTGAGGCTCAAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCATGGTCGAGAAAGAGTTGCCTGAATCGGCACCTGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAATGCTTCTGTTAAGTTGAGCAAGCGCAATCACTG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACAGCCCGCCCTTATCAGCAGGCGTTGTTCGAGGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC

>NC_008639|3|4|1625830-1633049|CRISPRCasFinder
	AGGCTATCCGTATCTGCGCTTTCACGTCTGTAAGCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGTCATTGATGGCCGATGATTTCCGTGAAATAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGGCCAAATCGACCACATCGACGGCGACGGTCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGATGTCGCGTTCCGGCACGACGCGCTCAAAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGCATCCACGGCAGTTCAGGGGAGGGATTCGGTTAT
GTTTCAATCCACGCTCCCGCAGGGGGCGCGACGGTGTCACTTACGGTTGTGTTTTTTGATCGGAATCGATTCAATCCACGCCGCCCGCCAGGGGGCGCTACCATTGAATACTACAAAGATGGAACCTCAACTACTCGTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATGCTTGCCATTACCCTGATCGCAAGCCACCCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAGGTGATTGTGATCACACACCTGCCAAGCAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCGGATTGTACTCTCTTGCCAAGTGGGTGATCGGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGTTGTCCAGGCCTTGCACGACCTCAATCAACGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCGTGATCAAGGGTATGCAGGTGAGCGTAGACATC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GAAGCTCAGCGATGCGGAAACCGTAATCAACGAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACTTGATTTTCATTGGTCTTATGCCGGGCAAAAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTTTTATCCTTTGTCCGGAGCTTCATCGGTGTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCAACAGCATCGCCCTGCTTGAAACCACCGAGCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTCCTTGGTGCGGCGGACGCAGATGAACTGCTCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AACACCCGATGGCTTATAGGCCTGTTTTTCAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGATATGTTTTATGCGGTATGGGACGGGTATATA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTAATGCTCCCGATGGAGTACGATCCAAAAAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGGACTGATGAAAAAGCACGTCTTAACATACCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATACTGAGCCTGTAGGGTTTTATCATCCTGTTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAAGGTAAGCCAGATAAGCCAGATCAGAACCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAATCAAGATAGAGTATTATGAGTACCTTTACGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTCTTTCCATATTGCATGACGTGTCCAGTACTCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACTTGGCCGCAAGCTTGAGAATATCGCAGTTGTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTAACATAAATGTCAATTTTCGGACAACCAGTTTGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTATCAACACCAATGTTTTTAATGTAGTTGCGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTCGGCAAGCATTTCAGGTACAGCGCATGTATGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATTATCGTAATCCATTGTTGACAGCAAAGTGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCGATCTTATCGGATCGTTTGCCACTTTGACAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGGAATAGGTGCAAACAAAATGACACTTGGAAACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGTAAAGGAGATGTGCGACGCCATAAAATGGGCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAGCACAAGACGCTGCTCGGGTGTATGCTGCAG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TATTGATGTCGGGTTTTGGCACGACGAGTACACT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTACTGTTGTAATAGTGGCAGTGGTAATTTTTAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACACAATTGTGGGCGCCCGCCAAAAAACGATATA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAGGCTCCGGTTGACAACCGCGCTGCTTAACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTCCATACCGACTGGTGAAATCACTGGTATG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAAGCGACATAGAAGAGCGCATTTATGGAGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCACTTGATCCAGAGCATGCAGCGCGAGTTGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGTATACTCAGATAAGGCCGTCAGAAAGCCTAAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGCACCACATAGTACCTGCAGGAGACATGCGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAAACAGATCAAGTGGGCAACTGACATCAAAGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTTTAACCTGGATTTCGACACCGCATTTCTCGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTGCTTTTGCGTATTTTTCTGCCGCCCAACGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTTTTGTCATTGCGGTTTGGTGTTGCGCACGCAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TACCGCAGGTCAGACTGTCACGATTGGCCTTGCAGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTAATTAGTGGATGAGACAATGACAACAAAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGCCTTCAATATCAGGGTTCACGCCCTGTATCGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTTCCCCCTTGATAATCTCGCTCATCTGCCCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TATGAGCGTTTACGACATTAAAGCCGGAGGATGGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATTACCGCCATGTCGCTGACGTACCTCACCCT
GTTTCAATCCACGCGCCTGCAGGGGGCGCGAC	CTTAACCATGAGGACGACGCTCTTGAGGGTATGGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGAATTTCAATGCTCCTGGATAAGATGTAAGAGTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATTGATCAAGAAGTGAAGCGCAAAAAGATAGACGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TAATACTGGTATATTCGATGAGGCTGGTGAATACCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGAGAATCTACCATCTGATCAAAGTCTACATCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ACAATTCTGCAGCAAAAGAAGCTCAAGCAAACAGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCCATATATCCAAAGGCTGCGGGTTTGTTGAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTAGCCGGGAGCGATGATAATCTTGGCCGTGTAGCC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACTCCGCGCAACTGTCCCGGCCTTGTCGGCCT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCGGCATCAGCTCTGTCGAGTACACCATTGCCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTCGTTCACATCCTCGAGGATTGGCAGGACTGGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGACGATTACGCTATCCACCAGCTTCGAGAGCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACCGAACATTACAAAGATGGAACCTCCACAACTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AACCAACCAGACTGGGCAGACGTCCAGATGGTAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GACCTTTGGGATATGGGTTCACGATGGGCGACAATAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAGCCGGGGTATAGAGCTTTCAAGCAGCTTGCCTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAACCGGGATGTGCAGTCCGTGCGAGATCAGCTTA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTGATGCCGCACCGGTTCCCCTTCAAGTTCGACTG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCCTCATAAGAAGATGCCGGGACGCCTTTTGTCTC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTGGCTGGTGCAAGACGGAGGAAAGCTATGATAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGGATCGATGCCGATACTCCGTCTGTCGTAATG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTTATGTCGTTGATCGTGTATAGCCCGACGATAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CATGCAGACCACCTGCGCTGACGAGCAGGAAGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GACGGCTTTACGGTAGATCGGGCAAATGATGCGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCATGTGTCGAACAGATCACCATCGAAGAGAACCGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGGCAGAGGGCTGAGTTGCAAGAGCGCCTTGATGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GATAACAAAATTACCTGCAAGCACAAAAAAAAGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGAGGCGCCCCGGCGGAACGTGCTGAGTTTTACCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGAGGACATCTTCATCAATTCTTCATCTGTGATT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCAAAAAAATTCATTAAAAAGTATTGTGATTGCAGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGCCAATGCAGCCGGGAACCGTAACCCCGGATC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATGGCAAAGCCTGAAAAAATATTCATGCGCTTTGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTTTGCCGAAGGTGCCACAAAATCAAGCATCGCGGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGCAAGGAAGTCTTCCAAATTCCCTTTGTGTCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGCTGATGAACGACGAGCTATCAATTAAAAAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGAAGAGCAAAGCTTGCCGTTAATCCATTGTGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATTACCCGAATGGCCAACCATCCGAGTATCGCGAA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGATCAATATGGTCAGATTCCAGGATTGCGGAAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATAGTGAATTTTGTGAAAATCACATATAGGAGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTGGTACTTACTCCTTTTATGGGCGTAGGATCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TGCGGGAGCAGCTTGATGGCGGTGACGTTTTCGAC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TTCTGTCGCCGGCGGCGCTCAGGTGCTGCAGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GGATATTTGACTGACGTTAATGTGATCGATGGCGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAAGCGGAGTCGAGGATATGACAATCTCAGCCATT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAACTACGATCTTGGGGCGGAGGTTGTTCGGAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCCGGATTCGACGTTTGTCGGGTAGCTTCCGGCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCTCGCGGAGTTGTACATCTCGACCAACAAGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TCATACCATTGTGTGTTGATATGATGCGCAGAGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AAGAAGGTTTATTATAAGCCTTTTGCGCCTCATGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	TAACTTTAGCATGGTACCATCTGTAAGTGTACCGA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGAATTTGCGACAATGTCGCGAAACCCTGGAGTCG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCAACAATTGTTCCCGTTGCTGAATCAGTAACGGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GTTATCCGCAAAAACAAATTCGCAATCCTCAACA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	ATCTGCGCTTTTACATCAGCAAGCTGCACAGGAT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CCCTCTATCTTTGATCGGTTTTGCTCAAGAGACG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CTCACGACATCGGGGTGCGGGAACTGATGAGCGG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	AGCCATACGGACACAGCCGCGCAACATTCCGTT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGTTTCTCGATCAAGTGATCGGCGATATACGGCA
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CGATGGCGCAGGCCAAAACCGTTGAGGCTCAAGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	GCATGGTCGAGAAAGAGTTGCCTGAATCGGCACCTGT
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CAATGCTTCTGTTAAGTTGAGCAAGCGCAATCACTG
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC	CACAGCCCGCCCTTATCAGCAGGCGTTGTTCGAGGC
GTTTCAATCCACGCGCCCGCAGGGGGCGCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008639.1\|WP_011745273.1\|1623619_1625194_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
NC_008639.1\|WP_041467258.1\|1620638_1620851_+\|YgiT-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|274806
NC_008639.1\|WP_011745278.1\|1636336_1638061_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09642_cas8c_CAS-I-C	gnl\|CDD\|187887
NC_008639.1\|WP_011745274.1\|1633226_1633517_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_008639.1\|WP_011745265.1\|1614835_1615459_-\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NC_008639.1\|WP_011745271.1\|1620981_1621947_-\|transposase	unknown	unknown	gnl\|CDD\|376616
NC_008639.1\|WP_011745276.1\|1634548_1635193_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NC_008639.1\|WP_011745277.1\|1635195_1636296_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|274216
NC_008639.1\|WP_011745280.1\|1638793_1640797_-\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_008639.1\|WP_011745282.1\|1641027_1642041_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_008639.1\|WP_011745279.1\|1638057_1638771_-\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09651_cas5_CAS-I-C	gnl\|CDD\|187534
NC_008639.1\|WP_041467608.1\|1643365_1643575_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NC_008639.1\|WP_011745275.1\|1633520_1634552_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_008639.1\|WP_011745269.1\|1619046_1620012_-\|transposase	unknown	unknown	gnl\|CDD\|376616
NC_008639.1\|WP_011745267.1\|1615990_1616458_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745268.1\|1616729_1617488_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NC_008639.1\|WP_041467605.1\|1622858_1623599_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|366760
NC_008639.1\|WP_011745281.1\|1640783_1641035_-\|CRISPR-associated-endonuclease-Cas3''	cas3HD	cd09641_cas3HD_CAS-I	gnl\|CDD\|193608
NC_008639.1\|WP_011745270.1\|1620312_1620642_+\|DUF4258-domain-containing-protein	unknown	unknown	gnl\|CDD\|379454
NC_008639.1\|WP_011745266.1\|1615473_1615782_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008639.1\|WP_011745273.1\|1623619_1625194_-\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	3.7075e-13
NC_008639.1\|WP_041467258.1\|1620638_1620851_+\|YgiT-type-zinc-finger-protein	gnl\|CDD\|274806	TIGR03831, hypothetical_protein, YgiT-type zinc finger domain. This domain model describes a small domain with two copies of a putative zinc-binding motif CXXC (usually CXXCG). Most member proteins consist largely of this domain or else carry an additional C-terminal helix-turn-helix domain, resembling that of the phage protein Cro and modeled by pfam01381.	5.69506e-09
NC_008639.1\|WP_011745278.1\|1636336_1638061_-\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|187887	cd09757, Cas8c_I-C, CRISPR/Cas system-associated protein Cas8c. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Zn-finger domain containing protein, distant homologs of Cas8 proteins; signature gene for I-C subtype; also known as Csd1 family.	0
NC_008639.1\|WP_011745274.1\|1633226_1633517_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.53254e-34
NC_008639.1\|WP_011745265.1\|1614835_1615459_-\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	1.01826e-44
NC_008639.1\|WP_011745271.1\|1620981_1621947_-\|transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	3.111e-09
NC_008639.1\|WP_011745276.1\|1634548_1635193_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	5.02087e-47
NC_008639.1\|WP_011745280.1\|1638793_1640797_-\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.59513e-56
NC_008639.1\|WP_011745282.1\|1641027_1642041_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	2.40272e-52
NC_008639.1\|WP_011745279.1\|1638057_1638771_-\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	5.7417e-103
NC_008639.1\|WP_041467608.1\|1643365_1643575_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	5.33261e-07
NC_008639.1\|WP_011745275.1\|1633520_1634552_-\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NC_008639.1\|WP_011745269.1\|1619046_1620012_-\|transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	3.4388e-09
NC_008639.1\|WP_011745277.1\|1635195_1636296_-\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|274216	TIGR02589, conserved_hypothetical_protein, CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csd2 protein of the Dvulg subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02590, the Csh2 protein of the Hmari CRISPR subtype.	3.04214e-133
NC_008639.1\|WP_011745268.1\|1616729_1617488_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	1.23779e-65
NC_008639.1\|WP_041467605.1\|1622858_1623599_-\|ATP-binding-protein	gnl\|CDD\|366760	pfam01695, IstB_IS21, IstB-like ATP binding protein. This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.	1.90385e-57
NC_008639.1\|WP_011745270.1\|1620312_1620642_+\|DUF4258-domain-containing-protein	gnl\|CDD\|379454	pfam14076, DUF4258, Domain of unknown function (DUF4258). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 95 and 124 amino acids in length.	1.45512e-18
NC_008639.1\|WP_011745281.1\|1640783_1641035_-\|CRISPR-associated-endonuclease-Cas3''	gnl\|CDD\|193608	cd09641, Cas3''_I, CRISPR/Cas system-associated protein Cas3''. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; HD-like nuclease, specifically digesting double-stranded oligonucleotides and preferably cleaving at G:C pairs; signature gene for Type I.	7.33345e-10

>NC_008639.1|WP_011745273.1|1623619_1625194_-|IS21-family-transposase
MANKALTMLQVRRILKLLMEECSQREIHRSTGIHRVTIKSYLHRFTSSGKPFSELYALSDYDLSVLVHPPRSTKTSDERYADLQPQLQRFSDELNKTNSHVTKQVLWEEYLQDRPTGYQYSQFCYHVDQYIKQHAVTMPQQHEPGYRLQIDFAGDPLWIIDPLTRERIKCPVLVCTLPCSSFFYVEPLSSCRQEHLIPALNRALAYFGGVPKNILSDNMKQVVTTASRYEPVFNDLMEQWALHYQTNMQATRAVRPKDKPSVEGSVHHAYQQIYARLRNEEFTSLSALTYRVRHLLDTANDRLMTDYGKSRRQRFIELEQEFLQPLPLTDFVYKRETTAKVKKNYHVILGEDRCQYSVPHEHIGKIVKLIYDESVVEVFLDFQRIALHQRIVGRRGIYRTVEEHMPESHRRYHQQQGWTEEDFTSKAAAVGPCTEEAVLRLLSSKAFAQQSFDACLGILRLQKKYGTTRLEAACSVALQVPRLNYRLVNNILENNRDKVSVAAGEQRASLLPLHDNIRGKEVYN
>NC_008639.1|WP_041467605.1|1622858_1623599_-|ATP-binding-protein
MNTQLTLDQLRSMNLYGMANAYEAAMTLPVHEQPAADMLLGKLVDAEQLFRKEQSTKRYLLQSKIRYPAILEQVHCNAARNLTRDQLLSLSDCSFIRRGENILITGATGCGKSYLACALGRQACSLGYRTLYFGMNRFLERIAQTKLDGTFVRVLNQIERTHLIILDDFGLQPLDATTRIALLQILEDRYGKQAIMITSQLPVAQWHDVIGEPTIADGIMDRLVGNAHRLELKGESLRRKKLDKNV
>NC_008639.1|WP_011745271.1|1620981_1621947_-|transposase
MPRGARLDVAGTLHHVIIRGIEQGSIVRDDTDRKMFLDRMGLLAASSGTSIYAFALMTNHAHILLKSGPNGLSGYMRRLLSWYAQYFNRRHQRVGHLFQNRYKSIICEEEAYFDKLVAYIHLNPLRAGLAETMQQLASYPWSGHAVLMNKVRYEWMDRDYVLRFFGSREGLARNAYLRFLEEELCIDREKELSGGGLVRSQGGWSKVQSMRKRGEKALGDERILGGDDFVRRVLKEGEEDKDALLPENERMKRFKEAVEQVCEDAGVTKTYLLSGSRGGKLPLLRKELAMKSVYEYGISLAETARQLGVTTNAVSYMLKSR
>NC_008639.1|WP_041467258.1|1620638_1620851_+|YgiT-type-zinc-finger-protein
MNCMYCKGNMERGIAPFHIDRKGYHITLDRIPAWVCTQCGEVYFDESEVEAIQEVLCTLDQRTEKMAKSA
>NC_008639.1|WP_011745270.1|1620312_1620642_+|DUF4258-domain-containing-protein
MTDYSDIVSSVKKSAAKRIIYLPHAVRQMSRPDRIILVAEVRNVVERGELVEDYPEDVRGHSCLLLGYKLDDTPIHVVCSPKGDYLAIITAYIPNPEEWECDYKRRRRR
>NC_008639.1|WP_011745269.1|1619046_1620012_-|transposase
MPRGARLDVAGTLHHVIIRGIEQGSIVRDDTDRKMFLDRMGLLAASSGTSIYAFALMTNHAHILLKSGPNGLSGYMRRLLSWYAQYFNRRHQRVGHLFQNRYKSIICEEEAYFDKLVAYIHLNPLRAGLAETMQQLASYPWSGHAVLMNKVRYEWMDRDYVLRFFGSREGLARNAYLRFLEEELCIDREKELSGGGLVRSQGGWSKVQSMRKRGEKALGDERILGGDDFVRRVLKEGEEDKDALLPENERMKRFKEAVEQVCEDAGITKTYFLSGSRGGKLPLLRKELAMKSVYEYGISLAETARQLGVTTNAVSYMLKSR
>NC_008639.1|WP_011745268.1|1616729_1617488_+|SagB/ThcOx-family-dehydrogenase
MNSTAIQTCRSFLKDTIRQTIDFSRTDQNLWIPPPPVEKPYSQDMKRIELPKIETLQTIGQIDLKTAIARRESCRTYSKTPLTLEELSLLLWATQGVRRKLDAGHALRTVPSAGCRHAFETYLCVLNVIGLEKGIYRYLPLEHQLLFEFDADNLEHKITRAALGQPFTGEAAVTFIWTAIPYRMEWRYGLAAHKVIALDAGHVCQNLYLAAEAIGAGTCAIAAYDQAAMDKLLNIDGEEEFTIYLAPVGKKR
>NC_008639.1|WP_011745267.1|1615990_1616458_-|hypothetical-protein
MAKQSLLQEMKKTFMLHAIAAHFSNGMIPVAVLYLLLTISTGDVFFERTVEHLIIIVLMAIPVSFFSGIYDWKKKYRGAKAPVFMKKIRLSGILFVLCALTVGIRLSTPDVMTGTGILHWVYIVLLLGMLPIVTLLGHYGGKLASQGRQQQPKAS
>NC_008639.1|WP_011745266.1|1615473_1615782_-|hypothetical-protein
MPVDHRSSRSLSEAFIDSVMSEACQPLYIGCFALLVRRIDGVSVRFGLQNLYGFMPFFAFAAEISFSQAWVCRKMQIALFIVDRLFLKLSVVNKMLEERKDV
>NC_008639.1|WP_011745265.1|1614835_1615459_-|LysE-family-translocator
MIDQHVLFMFFVSSVVLSLSPGPDNLFVMAQSARNGRLAGMMVTLGLCTGLVLHTLAVAFGLAALVAASAVAFTVLKFAGAAYLLFLAWKAFHADVEKDSSDVSQVERGKLYRRGIVMNISNPKVSLFFLAFLPQFADPKNGPLVPQLLFLGAIFIVAALLVFSLLFFVAGGAGARFRRSAKARRVVNRIAGTIFAGFALKLLFTER
>NC_008639.1|WP_011745274.1|1633226_1633517_-|CRISPR-associated-endonuclease-Cas2
MLVLVTYDVNTETPAGRRRLRRIAKTCQNYGQRVQFSVFECNVDPSQWVKLRAKLMHEMDHAHDSLRFYFLGSNWQNRIEHEGAKEPRDLEGPLIL
>NC_008639.1|WP_011745275.1|1633520_1634552_-|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTLFVTTQGAYLSKEGECAVIKIDKVEKVRLPLHMLDGIICFGQITCSPFLMGHCAEKGVTVTFLTEYGKFLCQVQGPTKGNILLRRAQYRQADNYQQSAMLARAFVIGKIGNSRVTLARAMRDHPEKVDGEKMHYAQQLLAGCIKKLGDETDQERIRGIEGEAGRIYFEVFDQCITTSDPLFRFNGRNRRPPVDRVNCLLSFLYTLVTHDIRSALESCGLDPAAGFLHKDRPGRPSLALDMLEEFRSYIADRMALSLINRGQIQANDFTVSDTGAVLMKDDARKTLLTAYQKRKQEEIEHPYVREKMAVGLIWHMQAMLLARYIRGDIDMYPPFVWR
>NC_008639.1|WP_011745276.1|1634548_1635193_-|CRISPR-associated-protein-Cas4
MYDESDFIALSALQHFVYCPRQCALIHIEQVWAENSYTAEGREMHERVDDGETSYRPGVRTTRSVPLRSAMLGASGIADVVEWHKRNGREEPFPIEYKRGRQKKHDADKVQLCAQAICLEEMLGIAIPSGALFYGQTKRRFEVVFDAMLREKTAATAECVHELFRNGVTPLPEPGPKCNQCSLQELCLPEVVVHSRSAKNYVHKLLRELSEDEI
>NC_008639.1|WP_011745277.1|1635195_1636296_-|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MTTVDKRYDFVLLFDVQDGNPNGDPDAGNFPRIDAETGIGLVTDVCLKRKVRNFVQINDVQQPGYDIYVKEKAVLGLAHFKAFKELGISTGEMSKKVINDQEMIEIFSDLTLPEGVSFAESDEHGVLSIAADADKNEIKDWMKAEKESLSKNVIKVISEALKEAKPRKPTAEETSRGKEKMCQDYYDIRTFGAVMSLKSAPNCGQVRGPIQMTFARSVEPIVALEHSITRMAVATEAEAEKQSGDNRTMGRKYTVPYGLYRAHGFVSANLAHQTGFSENDLDLFWNALLNMFDHDRSAARGLMSTRGLYVFEHSSVLGNAPASQLFERITVKRKEDSEGPARSFKEYDVLIDESSLGEVKLLRKLG
>NC_008639.1|WP_011745278.1|1636336_1638061_-|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MILHALYDYYQRKAADPESGIAPEGFEWKEIPFVIVIDQVGNFITFEDTREGDGKKKWAKKYLLPKSIHRPGSNSWMTSFLLWDHYGYVLGHARGESDKDQKMAHKQMPTFIKKIQALPSEVKEDEGVIAVIRFYENGGYEKVKSAHNWSECAKIVGCNLSFRIDGESDLVPCRDAVRKYVASQCSDNTDGVSGLCLITGENAAIARIHSDTPINKDSKKFVSFQKSSGYDSYGKEQAFNAPISKSAEFAYTTTMNMLLGKESKNKVQVGDATTVFWSQKQEAFEEVFPALFGYPKDDPDADVKAVRALYEGVNTGHANMDSDTRFYVLGLAPNSARISVRFWHTGTIAEFAGNIRQHFDDLAIIRSQKDSDHFSMFWLLSAMAHEGKVDNVPPNLSGQIFQSVITGGLYPATMLQQAIRRIRATQAKDLKNRSTQASILKAYLNRFSRIYKTKEKEINVALDPTNDNPGYRLGRLFAVLEKIQEEASPGINATIRDRFYGAASSTPVTVFPQLLKLKNHHLSKLKNVGRRVNFERILASIFDGIGNDMPSHLSMEDQARFAIGYYHQRQDFKK
>NC_008639.1|WP_011745279.1|1638057_1638771_-|type-I-C-CRISPR-associated-protein-Cas5
MEHWNKQFCLEVKGDYACFTRPEMKVERVSYDVITPSATRGIFEAIFWKPAIRWRIRKIEVLNPIKWISVRRNEVGQTASERSDCIFIEVARQQRAGLFLRDVAYRLHAELEFISPSERPDAKHPVPEALLDGWETEELRKDENPGKYYGIFERRARKGQCFNQPYLGCREFSCEFRLVDDLSNEPAPISETRNLGYMLYDLDFQKNVKEPPPAFFRVSMENGVINVPAWDSEEVRK
>NC_008639.1|WP_011745280.1|1638793_1640797_-|CRISPR-associated-helicase-Cas3'
MGRIDHSAAGAILATDKNKWIGRILGYLIAGHHTGLPDWHKEPGTKGDPLSERLSNPEHLMNALKGNPPENILNTALPSSLPCKSQDGGSELVHLWIRMLYSCLVDADFLDTERFMNPEKSELRPNEVDLVMLRERLDVYMAAKENGALDTPVNRARKEILRECRDKGRSLEPGLFSLTVPTGGGKTLASMAFALEHAIRHGKKRIIVAIPYTSIIEQTAAVYREVFGDDTVLEHHSNLDPARETAESRLATENWDAPIIVTTNVQLFESLFAARSSACRKLHNIVNSVVVLDETQMLPTDFLQPIVSVIKSLSTYFRASVVLCTATQPVLSGKVGTGKDILNGFEGGSVRELMSDPEKLFSVFQRVRVRMLGQAGERYEWTEIARQLQEHEQVLCIVNTRKDCRELHAQMPAGTVHLSALMCPEHRSKVISEVKSKLMTGELVRVVSTQLLEAGVDIDFPTVYRSFSGLDSIAQAAGRCNREGRLECGDVVVFNPPKPSPSGRLMKAENAAQELFRTDPELASSLMPEAFSRYFIRYFSGLNGFDTEQIMDLLAGNDALKYQIQFRTAAKRFKLIDDTLQHGIIVRYRDGKANIVALIDQLRFGGSNRKLMRQLQRYAVNVYDPDLKQLRGNGLIEEVNGVWVQTADSLYDPVFGLNIDATLNFVY
>NC_008639.1|WP_011745281.1|1640783_1641035_-|CRISPR-associated-endonuclease-Cas3''
MNKERKPVAHLRQNESDEWLEHELNDHLAGVATIATGFASEFGNADWAMAAGLLHDLGKYNPRWQDYIRKSNGDYLEDSDGQD
>NC_008639.1|WP_011745282.1|1641027_1642041_-|WYL-domain-containing-protein
MRQSRPPLLRMQYIDRELRNTCYPNCSKVACFFEVSSKSIQRDIEYMRDVLNAPIDYDKKKKGYFYKQHWSFLASSFLNREEAAALIATKKVLSQYQGTPYYNEISSALDKVLQYLPTSNSENGIFDIYSFEQPASSQINTKNFAQLEEAIRTSRKVAITYHASSNQAETERTVHPYRLHFDQSTSTWYLIAYCELRQGIRTFAVNRIITLAPDASEFSIPESFSIEHYLEQTFDQCSGVEEHTIVIRFTPYQSQWIKEHRWHPTQQIEEHEDGSVTLNLNVAALDAVKRWVMRYGKEAEVLEPEELRELIRKEVKGMGEMYAMTELINRNKFEGNE
>NC_008639.1|WP_041467608.1|1643365_1643575_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MNFTIEQEQESDGRWLAEVPELPGVLAYGATSLEAMSRAEVLALRVIAERLEHNESRPFAINISIPVMA

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Crispr_ID: NC_008639_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008639_4

2377889-2379138

TypeIII

Consensus_repeat	Method
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CRISPRCasFinder
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CRT
TGAAACGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGC	PILER-CR
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	PILER-CR

16 spacers

csx15,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,csx1,cas6,cas1,cas2

The CRISPR arrays of NC_008639_4

>merge|NC_008639|4|2377889-2379138|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
TATATCACCCTCTATGAGTGCAATAAGATATAAAGCATACCAAGCCCGACCGTATGGAGAGGGAGTGCTAATGATACGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGCTATCAAGTTTTCGTAAACGGTATGATGGAGCTTGAAACGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGAAAAACTCCACCGGAATTGTTTCGGAATACAGAATTTTAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTCTTGGAAAGTGGGAACCACTTGCTAAAGAATACGATGAGATGGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTTTTTAGTAGGAAGGTCCTCGATCATTTAAAAGATTTTGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGGATGTACGGCATTCTTCGTGAGTACTTGTTCCGTTGCGGCTGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGGCGAGCCGGGGGAGGTTGTTGGTGTTGTGATGATAACAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGCCCGCCTCGCTTAAATCGGTCAAGGTCTCCTTGGCGTTAAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGAACTACAAAGAAGGTCAGATTCACTTATTGTCCGATGCTCTTGAGAACAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTTGTCGCAACGGGTAAGCTTGACGTCCCGCAGATGCTGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTCGCCGTGCAGGCGATTGTTGGGGGCATTCTCTATGTTCGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTTTAAGCAGGAACGAAATTGCAATTATCAGAATTGGTTTTTTAAAGGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTGATTGTTGATCACGGCGTCGCCGAAGTATTCTCTGCATGAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGCAATCCGGTGGGGGTCGTTCTGGCAACCGACACAGTCGCAAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTGCAGAATATCTGAAAGATGCAAGAACAATCACGAACGGAAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGACGCGCAATATGGTCGTTGCGCAGAAAGCGATTAAAGTATGGTTTCAATCCTCTATGAGTGCAATAAGATATAAAG

>NC_008639|4|5|2377889-2379138|CRISPRCasFinder
TATATCACCCTCTATGAGTGCAATAAGATATAAAG	CATACCAAGCCCGACCGTATGGAGAGGGAGTGCTAATGATAC
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CTATCAAGTTTTCGTAAACGGTATGATGGAGCTTGAAAC
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AAAAACTCCACCGGAATTGTTTCGGAATACAGAATTTTA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCTTGGAAAGTGGGAACCACTTGCTAAAGAATACGATGAGATG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTTTAGTAGGAAGGTCCTCGATCATTTAAAAGATTTT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GATGTACGGCATTCTTCGTGAGTACTTGTTCCGTTGCGGCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GCGAGCCGGGGGAGGTTGTTGGTGTTGTGATGATAACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CCCGCCTCGCTTAAATCGGTCAAGGTCTCCTTGGCGTTAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AACTACAAAGAAGGTCAGATTCACTTATTGTCCGATGCTCTTGAGAACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTGTCGCAACGGGTAAGCTTGACGTCCCGCAGATGCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCGCCGTGCAGGCGATTGTTGGGGGCATTCTCTATGTTC
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTAAGCAGGAACGAAATTGCAATTATCAGAATTGGTTTTTTAAAG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGATTGTTGATCACGGCGTCGCCGAAGTATTCTCTGCATGA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CAATCCGGTGGGGGTCGTTCTGGCAACCGACACAGTCGCAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGCAGAATATCTGAAAGATGCAAGAACAATCACGAACGGAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	ACGCGCAATATGGTCGTTGCGCAGAAAGCGATTAAAGTATG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG

>NC_008639|4|3|2377889-2379138|CRT
TATATCACCCTCTATGAGTGCAATAAGATATAAAG	CATACCAAGCCCGACCGTATGGAGAGGGAGTGCTAATGATAC
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CTATCAAGTTTTCGTAAACGGTATGATGGAGCTTGAAAC
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AAAAACTCCACCGGAATTGTTTCGGAATACAGAATTTTA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCTTGGAAAGTGGGAACCACTTGCTAAAGAATACGATGAGATG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTTTAGTAGGAAGGTCCTCGATCATTTAAAAGATTTT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GATGTACGGCATTCTTCGTGAGTACTTGTTCCGTTGCGGCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GCGAGCCGGGGGAGGTTGTTGGTGTTGTGATGATAACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CCCGCCTCGCTTAAATCGGTCAAGGTCTCCTTGGCGTTAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AACTACAAAGAAGGTCAGATTCACTTATTGTCCGATGCTCTTGAGAACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTGTCGCAACGGGTAAGCTTGACGTCCCGCAGATGCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCGCCGTGCAGGCGATTGTTGGGGGCATTCTCTATGTTC
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTAAGCAGGAACGAAATTGCAATTATCAGAATTGGTTTTTTAAAG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGATTGTTGATCACGGCGTCGCCGAAGTATTCTCTGCATGA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CAATCCGGTGGGGGTCGTTCTGGCAACCGACACAGTCGCAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGCAGAATATCTGAAAGATGCAAGAACAATCACGAACGGAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	ACGCGCAATATGGTCGTTGCGCAGAAAGCGATTAAAGTATG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG

>NC_008639|4|4|2377897-2378075|PILER-CR
CCTCTATGAGTGCAATAAGATATAAAGCATACCAAGCCCGAC	CGTATGGAGAGGGAGTGCTAATGATACGTTTCAAT
CCTCTATGAGTGCAATAAGATATAAAGCTATCAAGTTTTCGT	AAACGGTATGATGGAGCTTGAAACGTTTCAAT
CCTCTATGAGTGCAATAAGATATAAAGAAAAACTCCACCGGAATTGTTTCGGAATACAGAATTTTAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCTTGGAAAGTGGGAACCACTTGCTAAAGAATACGATGAGATG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTTTAGTAGGAAGGTCCTCGATCATTTAAAAGATTTT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GATGTACGGCATTCTTCGTGAGTACTTGTTCCGTTGCGGCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GCGAGCCGGGGGAGGTTGTTGGTGTTGTGATGATAACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CCCGCCTCGCTTAAATCGGTCAAGGTCTCCTTGGCGTTAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AACTACAAAGAAGGTCAGATTCACTTATTGTCCGATGCTCTTGAGAACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTGTCGCAACGGGTAAGCTTGACGTCCCGCAGATGCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCGCCGTGCAGGCGATTGTTGGGGGCATTCTCTATGTTC
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTAAGCAGGAACGAAATTGCAATTATCAGAATTGGTTTTTTAAAG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGATTGTTGATCACGGCGTCGCCGAAGTATTCTCTGCATGA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CAATCCGGTGGGGGTCGTTCTGGCAACCGACACAGTCGCAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGCAGAATATCTGAAAGATGCAAGAACAATCACGAACGGAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	ACGCGCAATATGGTCGTTGCGCAGAAAGCGATTAAAGTATG


>NC_008639|4|5|2378114-2379138|PILER-CR
	CGTATGGAGAGGGAGTGCTAATGATACGTTTCAAT
CCTCTATGAGTGCAATAAGATATAAAGCTATCAAGTTTTCGT	AAACGGTATGATGGAGCTTGAAACGTTTCAAT
CCTCTATGAGTGCAATAAGATATAAAGAAAAACTCCACCGGAATTGTTTCGGAATACAGAATTTTAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCTTGGAAAGTGGGAACCACTTGCTAAAGAATACGATGAGATG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTTTAGTAGGAAGGTCCTCGATCATTTAAAAGATTTT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GATGTACGGCATTCTTCGTGAGTACTTGTTCCGTTGCGGCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GCGAGCCGGGGGAGGTTGTTGGTGTTGTGATGATAACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CCCGCCTCGCTTAAATCGGTCAAGGTCTCCTTGGCGTTAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AACTACAAAGAAGGTCAGATTCACTTATTGTCCGATGCTCTTGAGAACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTGTCGCAACGGGTAAGCTTGACGTCCCGCAGATGCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCGCCGTGCAGGCGATTGTTGGGGGCATTCTCTATGTTC
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTAAGCAGGAACGAAATTGCAATTATCAGAATTGGTTTTTTAAAG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGATTGTTGATCACGGCGTCGCCGAAGTATTCTCTGCATGA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CAATCCGGTGGGGGTCGTTCTGGCAACCGACACAGTCGCAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGCAGAATATCTGAAAGATGCAAGAACAATCACGAACGGAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	ACGCGCAATATGGTCGTTGCGCAGAAAGCGATTAAAGTATG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008639.1\|WP_011745867.1\|2376348_2377212_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378236
NC_008639.1\|WP_011745859.1\|2365516_2367130_-\|hypothetical-protein	csx1	cd09747_csx1_CAS-III	gnl\|CDD\|187878
NC_008639.1\|WP_011745861.1\|2369101_2370166_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|380071
NC_008639.1\|WP_011745863.1\|2371046_2371523_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NC_008639.1\|WP_041467710.1\|2389058_2389454_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319947
NC_008639.1\|WP_011745870.1\|2384619_2384907_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745869.1\|2381638_2381923_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_008639.1\|WP_011745872.1\|2386426_2388055_-\|RelA/SpoT-domain-containing-protein	unknown	unknown	gnl\|CDD\|214934
NC_008639.1\|WP_011745862.1\|2370176_2371034_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_008639.1\|WP_011745866.1\|2375737_2376310_-\|hypothetical-protein	csx15	cd09766_csx15_CAS-I:CAS-III	gnl\|CDD\|187735
NC_008639.1\|WP_011745864.1\|2371522_2373811_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NC_008639.1\|WP_041467343.1\|2367138_2369109_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NC_008639.1\|WP_011745865.1\|2374659_2375253_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_041467347.1\|2390102_2390564_+\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_041467348.1\|2392524_2392800_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_008639.1\|WP_011745868.1\|2379402_2381598_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_008639.1\|WP_011745875.1\|2392803_2393847_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_008639.1\|WP_011745871.1\|2384903_2385551_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	unknown	unknown	gnl\|CDD\|378065
NC_008639.1\|WP_011745858.1\|2364699_2365503_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|187889
NC_008639.1\|WP_190271880.1\|2389692_2389830_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008639.1\|WP_011745875.1\|2392803_2393847_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	7.6e-95	312.3	0.0
NC_008639.1\|WP_011745859.1\|2365516_2367130_-\|hypothetical-protein	csx1	cd09747_csx1_CAS-III	2.3e-24	80.7	0.9
NC_008639.1\|WP_011745861.1\|2369101_2370166_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	4.8e-31	102.8	0.0
NC_008639.1\|WP_011745863.1\|2371046_2371523_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	4.3e-18	60.6	0.8
NC_008639.1\|WP_011745869.1\|2381638_2381923_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.6e-26	87.1	0.2
NC_008639.1\|WP_011745862.1\|2370176_2371034_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	2.4e-60	198.7	0.5
NC_008639.1\|WP_011745866.1\|2375737_2376310_-\|hypothetical-protein	csx15	cd09766_csx15_CAS-I:CAS-III	2.8e-39	127.7	0.1
NC_008639.1\|WP_011745864.1\|2371522_2373811_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	1.8e-87	289.1	0.1
NC_008639.1\|WP_041467343.1\|2367138_2369109_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	4.8e-19	63.5	5.9
NC_008639.1\|WP_011745868.1\|2379402_2381598_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	3.2e-90	297.1	0.1
NC_008639.1\|WP_041467348.1\|2392524_2392800_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.6e-30	99.9	0.1
NC_008639.1\|WP_011745858.1\|2364699_2365503_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	2.7e-47	156.4	0.0

Protein	Function_ID	Function_description	E-value
NC_008639.1\|WP_011745867.1\|2376348_2377212_-\|hypothetical-protein	gnl\|CDD\|378236	pfam09670, Cas_Cas02710, CRISPR-associated protein (Cas_Cas02710). Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	0.0031769
NC_008639.1\|WP_011745859.1\|2365516_2367130_-\|hypothetical-protein	gnl\|CDD\|187878	cd09747, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as Cas02710 family.	1.58196e-19
NC_008639.1\|WP_011745861.1\|2369101_2370166_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	3.60031e-33
NC_008639.1\|WP_011745863.1\|2371046_2371523_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	3.71242e-23
NC_008639.1\|WP_041467710.1\|2389058_2389454_-\|VOC-family-protein	gnl\|CDD\|319947	cd08359, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.33022e-34
NC_008639.1\|WP_011745869.1\|2381638_2381923_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.6855e-28
NC_008639.1\|WP_011745872.1\|2386426_2388055_-\|RelA/SpoT-domain-containing-protein	gnl\|CDD\|214934	smart00954, RelA_SpoT, Region found in RelA / SpoT proteins. The functions of Escherichia coli RelA and SpoT differ somewhat. RelA produces pppGpp (or ppGpp) from ATP and GTP (or GDP). SpoT degrades ppGpp, but may also act as a secondary ppGpp synthetase. The two proteins are strongly similar. In many species, a single homolog to SpoT and RelA appears reponsible for both ppGpp synthesis and ppGpp degradation. (p)ppGpp is a regulatory metabolite of the stringent response, but appears also to be involved in antibiotic biosynthesis in some species.	3.27023e-20
NC_008639.1\|WP_011745862.1\|2370176_2371034_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	5.65062e-64
NC_008639.1\|WP_011745866.1\|2375737_2376310_-\|hypothetical-protein	gnl\|CDD\|187735	cd09766, Csx15_I-U, CRISPR/Cas system-associated protein Csx15. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small protein loosely associated with CRISPR/Cas systems; some are fused to AAA ATPase domain, also known as TTE2665 family.	2.04612e-42
NC_008639.1\|WP_011745864.1\|2371522_2373811_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	1.03012e-88
NC_008639.1\|WP_041467343.1\|2367138_2369109_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	7.22703e-05
NC_008639.1\|WP_011745868.1\|2379402_2381598_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.83526e-106
NC_008639.1\|WP_041467348.1\|2392524_2392800_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.02121e-32
NC_008639.1\|WP_011745875.1\|2392803_2393847_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.13541e-107
NC_008639.1\|WP_011745871.1\|2384903_2385551_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	gnl\|CDD\|378065	pfam08843, AbiEii, Nucleotidyl transferase AbiEii toxin, Type IV TA system. This family was recently identified as belonging to the nucleotidyltransferase superfamily. AbiEii is the cognate toxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	9.75601e-08
NC_008639.1\|WP_011745858.1\|2364699_2365503_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	3.99026e-43

>NC_008639.1|WP_011745867.1|2376348_2377212_-|hypothetical-protein
MSTNPIQQKMRVQSLRRFAEGIVGRKNFGWWSLLYAALFFVVAGWFADGLAEFVDYVFSGQKRWILNYKLIVSAGLLFLFGWSIRNIAHDDHDEIAVNRDQPKPVRVLGLFLSNFLVRVDQTSHSGNSGDGFNKSALERAVSDSTFNRTMLLDTTWEMPFRAIEYHASSLERIELFTSSGGKCSSAESGLFIRLVAVLYPDVSVTEQIVDFEDLEVVFKAVEKLYADAEASGLKAQDVLVDITGGQKPNSIAAAIATLAVGRQFQYISTGDKVVRSYDVGYFQEDLS
>NC_008639.1|WP_011745866.1|2375737_2376310_-|hypothetical-protein
MNEFFTQNNLLVVFWYTAGIVSIIELLEYLVTRNIPWLLRLIRGLWRGVARRFRGDISQGARQLIINFSGHPVLPGQQQDIGQMMHWSSSEVINVSIGNVPEDHNFVPSIEKSVEKIPLSPEEWQSIPVVVIPSGYSQIWSVVMAELHGRLGYFPDVVRLRFSSSISNEKFEVAEIMNLREVRHNSRDKR
>NC_008639.1|WP_011745865.1|2374659_2375253_-|hypothetical-protein
MPLPDDKSFSQLKKSEFHLWFKKAEKAVKEVEYIHAELTMPAVNELRYAGYHVSNYLEDTELLDELNRAVGHCKRAIYDAYEASILYNIKEFRAFKNDYGTVVISEVLADYSDLHYRVTNILEFLRSIDKETKDQHYAACKEHHQELKDIIIKLDSARDELNKKIRIERKKSFFAIAGIALAVLSAVIAFLAYLGCH
>NC_008639.1|WP_011745864.1|2371522_2373811_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MTTSITGNDIIKLGFDLLREGTLSIVDIVDAFKLAGIQSTELKLSSLKSPFGGDRFFEPKQLSATEINYPVYDRVTDFSEIIPQDDDQGLTALERLGSFVATDADEKYSVFDLFKTVAAIQDCLRNPEEDKPFLLVSADFSGIQDTVYTISSKGALKTLRARSFMLELLTEHIIYEILSEVESERYAVVFSGGGGFGLLLPNSEESIRTINDYRTRINEWAFDEFSGRFFIAMDALPFGREELLSGMSFRNIRQTQADNLDRLKRRKFIDQFEQLFTPSMPKQLTVNTECQITRRDDMPDEFMFDLETETRMSLVPAKEREDDKWIWVSESCYHQFWIGDKLATAQSVVRSQKTPEGKEPYFKYPDATWSKENKSWVYYQIDDQQTKSADCWFMNDWTAGQPILYANYVRKHGELSEYAKKLENESLKEENPTAKPNHTATFQGLAASSCGADLIGALRMDVDDMGNLFSSIGSLTELSAKSRMLNLFFKVYLNQICAANLGGGFSYTDIAKKNYSVKNSHGDIGRNVSVIYAGGDDLFILGAWDETTELAFDIQRCFSLFTGETLNKEKKTVVEGLGISGGLTLHQPKFPLYQMAQKSGEAEHGAKNDIEIQNAEIEKNRISLFFDDSKRQCRLKIQEPYRYMLSMKWDLSSAFLLPLMKTYRECGNVAFQDGRMVLEIEKFSYQTIEKWFAVIEKYQESSMLYLPTMARVMKQVEENPRMDASLFKTLLGFLYTNDESKKNWISHLHVALNWLTYLRRKN
>NC_008639.1|WP_011745863.1|2371046_2371523_-|type-III-A-CRISPR-associated-protein-Csm2
MGYDFTEIYQINKQFDVDVHQIVSRIEGFGSFSSISEYELENLPKYAAVIAKAMKEKKKPVTPTQLRRFYTYVKSIDLANKQTKEDEQNFKDKYKLKFILPKIAGSSECESLEDLYKVLNACVNGDKIITVKDLRLFMEFFEAILDYHSTFKTQKKDN
>NC_008639.1|WP_011745862.1|2370176_2371034_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MADIERQIKLLGYIKITGIIEALTGLHIGGTADSIDKGGIDNPVIKNPVTNEPYIPGSSFRGRMRSLLEKKTAEYLSPMTGNKEIWMEIYKAEDEKYNNNKAQSTIDAMNSEVCRVFGNSASYESVPSVLIVRDALYTEKTRESYMQGGKGGLPITEAKMEIAVDRITAHALPRTIERVPAGAKFAFEIVYKIQSTSFICVIDEKGKPKEVKSYMADDKVIEKDIENILWALKQIEEHDGLGGNTSRGHGQVKFSIDPIKYEVFEDVSKQKIEKAIKNIKTTKEA
>NC_008639.1|WP_011745861.1|2369101_2370166_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MNTYIVHLYFKNALHVGAANSGIGIEATQDFIHSDTLWAAIANHWAILGKVGDISFDDFLNGFRTKHDDGIRHKEEPLFRISSAFPLTDNGRMYWLPKPLSVPMAFSKRNIEDRENQRKEYGKKVKQEKFIPLKVFKEWMNFEKNASDVGGAKREGISSGQMRPHATIDRISMRAQLFHSGITYFDKFAVRVGLYFLIQCGKTTKTALEKVFEVIYEAGAIGGNRNIGLGSLFEKPSLTEASEFADLFNTENTNAYCLLSLCYLSDGEIPNAETAVAYNHLLRKGWTGSLSVSLQRKRKTVYMFAEGSVFQTKLNGCLADITPDKIITPEWYGHHDVYRYGYALSVPIKIDLDD
>NC_008639.1|WP_041467343.1|2367138_2369109_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MTEHMESKIIELETLTSLFIKGKEENYGEGFIRIGNTLYFIDNDNLCEFIYKNTYDKDGSRIPNRPDYVEWYSYFISRQRGDDIVTHYKGFAKVFGLDDVNNERDIPEGYKEKSIQFFLSKTRLLQGNNDTQKQVLTEYKIGKGITLLEASTRNGNRFIQNGNKRHYVPGSSLKGAIRNAVLWKILTESSIQAWFLLFLTYHLPVSDFLKKIDENDYEEGEKIISKNAVFQNMNLIRNGHIDRKETKKLKKKYSEHLSGIQDATNSTLESKCFTGKIPYIPISDSDKIDQKKYLQSYNDRWNAANDTLRDFFRLVKVSDGNFVDDFELKGKIAKAVCRDIFGTPPKNKTYQKKFDIKLECAPKTVKVQFKISIDTELVRAFFPYRIPVYLQSVNGLMNVVDEFYREVAKFEALNYYNGVISIPDDLNSNDNRKAKLKVNTEVVYKLYNTIFGLEKNETLFRTGWGGGFMSKTQFLHMDMTDRVRVRDMVHYNGSPLAPKSRCLIIEGQNATEPLGWCKLRVLGDTKDLALPSIDAVKISTDILTEQPRQRGQQRQENRQNKERPVTEKEIHKSKAEAKAILKLVEKQTNLTTQVTYMKGQVVLAKVDECKPFESIKITIGNQSVCVVSGFIKQKGEEVKIKITKIENGKILEAKLL
>NC_008639.1|WP_011745859.1|2365516_2367130_-|hypothetical-protein
MKAEILNKRKKWLDKPAAQSLDDWPKKADELQGFTGTLKYFGIKQSSNEYEINSIGANSYFRQSLDLFKVVLEKQILKEDIGLPSLEMPPQYDALITIVGFSPEPIMHTVLALAPNKVYPIATIESAEYYKVPLNPESKQRDGKIWFFETIIKHYKEAQQSITVEPIVRNVSAIGSLETFKRVREIIQATKENNLNAKIALDITGGKKSADASAFLIAAIEEDIDIYYVDFEDYTGAKACCGTEFLNKLDNPYNIYNIQLLNKAKELFKYHNYQAAAQIFSEIDERLSSNELDNPVKFYLDDERSKVDKMKNAAICYMYWDRFDYECAQECQSVLSDKQKTQLNNLILFEGIGTKKERYQSCYLYDFIVDRILSAKRRALSDISLYEYEGDYHDAVFRYAQCLEILIETYITRKVSNYDPDVKSKSIYSISGKRELVFKGRKKSEKDNDGNRIDFQMDPLDDPENELRKKTKSLSERRDDFAHVRIQTQKSNIQEAEEVIMKFMEIVFEKTSEIIDHDLEEYAFYKYFDDYGSLCKS
>NC_008639.1|WP_011745858.1|2364699_2365503_-|CRISPR-associated-endoribonuclease-Cas6
MRITLELSHRNSSITLPINNSYLLSSLIYNIVDKSSSEYAGRLHAQGYRLQNKAFKLFAFSPLCPANRRKWEMQDDGTMSTRERVLHFTISSPKSEFIEHLVVGLLHEPYVFVGRERFRVECVRRLDCPEISGDMRFIALSPVVCATKHAGDLYAQYLFPGDDDFERVLFDNLCRKFEALHGRRFDGDNGNFHFTLDQDYVVRKNGKVQKLITIKEGKPDETRVKGLLAPFRLVAPAELMEVGYECGFGERNSQGFGLVKVDDCVRC
>NC_008639.1|WP_011745868.1|2379402_2381598_-|CRISPR-associated-endonuclease-Cas1
MGWLYNQMAMPETIFQAWYKVASNDGRPGWDNTSIQDYSLRLEENLKSLSHALLTGTYRQSPLLKLVMLKPDGKERVLLIPGVIDRVAQTAASIVLSPIIEAELGNCTFAYRPGISREGAAREIDRLHREGYQWVLDADIRNFFDNVRHDLLFQRLVELVDDKEMISLLHRWLTAEIVDGLNPRTRNTMGLPQGCPISPALANLYLDRFDETMEQQGFKLVRFADDYLVLCKTRPKAEAALKLSESALAELKLELHSDKTRITTFAEGFKYLGYLFIRSLVIPTKMHPEEWYDKLGKFRLRKKSVHALPADPETMTGETSQFELETDQGEKIELSKEELLQTEFGKKLLESLDKKQLNVDEFLEKISRQDEERQKEKREALKKLYSPFLNTLYLQEQGSLMRKDGERFSIEKDGSVINEVIVRRIEQVVIFGNVALTTPVMQYCLQNEIPVTFLSQHGKYFGRLEATTADNAEMQRFHFLRSIDEPFALETARSIVAAKISNSKTMIRRRKTVVQDRDSTLQNKMAYNLDIMADLALKAEASTDIDALRGIEGKASALYFECYGMLFSKNLPFHTRSFLRVRRPPTDPVNSLLSFGYTMLHTNIFSMVQASGLNPYIGFLHAERKGNPALVNDLVEEFRTIVDSLVLYTLNRGLLQEKDFYYRKDEPGCFLSNDARKRFLNIFETRMWQESRDGCTGKTLNFRRHIEKQVRIMREVIAGTRTQYDPYKLPV
>NC_008639.1|WP_011745869.1|2381638_2381923_-|CRISPR-associated-endonuclease-Cas2
MQFILVTYDIENDRRRTKIHKVLEGYGISVQYSVFECFLSDEDYAGLRIRLQKLMDPKHPLDSIRYYHLCRGCVEKVDVDGNRSFEIASPFIIT
>NC_008639.1|WP_011745870.1|2384619_2384907_-|hypothetical-protein
MKTLPVTPEMLQVARRVVWFREPEDELADPVHFLAHVMTYGTVDDLQMLQGIAGKNEFSEVLENPPPGVFDARSWAYWNLKCGRQPAPPLPIRIL
>NC_008639.1|WP_011745871.1|2384903_2385551_-|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein
MLPPSQLRLWPELDATPETFTLYGGTALALRFGHRVSVDFDFFSNKPFDPDELVDTLFYLKGAERLQVGPNTLTCRVDRGGPVLLSFFGGLGLGQVEAPDQAQGSTLFVASLLDIAGTKAAVVQKRAEVKDYLDMDALLQHGIDLPTVLAAGQVIYGCSFNPMITLKALSFFDDIPALPTDIRDRLCHAVDSVDPINLPVLKPYAERKIENGYNS
>NC_008639.1|WP_011745872.1|2386426_2388055_-|RelA/SpoT-domain-containing-protein
MKSKVSFEDACLHLKSIAGPTKMQLLALEDNCLNNNAVSKIYLTKYRIKKQESVYLKTKRKNKSLDEINDYGGLRLLCLFEDDIFDVHNDFVRMLHAKHYELKCCSAYNWNVKSIDKLRGEIDRYFDKNKYVFEKIKKTSGYKSVHYVVKQSGLDAEWIEVQLRTLVQDVWGELEHSISYKKGGIHPHIKKSFSLLSKELINIESLLSYLKEVNQKEIAGEEYYNKLVTPKYVFKYESQILPPCFEINVNLKVCYKQYWEIIESFETTSISHNWINQARAKLTEFNRNLTIDQLDENPELEYWIKMENAFLLFCDLKHEDSLKEYEKLLTKFGNRYCVHFRAGELYFILGHIEKALSSFDKAEDLIVVTEEIDHVNHYRIKTRLAYYYWSLGEEYIDISITEIKEAEEIFSKNKQLFDEAQYEQLVNNICWYKLEKYIIAVKKAESEETEENIRNADLAFEDVSSSYVVIDTLLKTNYISSHLLDTAAWYCYWVYKKTNDRAYLSKARDYALSINEKVKLTSYPFKSMKTHMNHIQAIMSAK
>NC_008639.1|WP_041467710.1|2389058_2389454_-|VOC-family-protein
MSVNAISTCITTEKVAESREFYVGHFNAEVTFDCGWYVNIRFAECSATLQFMAPREGQSPCNPAGLMYNISVPDVDEEYIRLTGEGLIPVMPLEDHPWGDRGFAVLDPNGVILYLFSERPASDEFKKYFLP
>NC_008639.1|WP_190271880.1|2389692_2389830_-|hypothetical-protein
MKIEEEEFCPRIDTNFHEEDLRLFCYFAISLSSYPAIQLSSLAFG
>NC_008639.1|WP_041467347.1|2390102_2390564_+|hypothetical-protein
MKIRVNSWTKLFLVQSSIQNPESKIQNLFTPLHPKARLDVGSAKRKQQTALISFRENSCQFVDKTLPLQSSIQNPKLKISSPLFIQKQGWIARWRNSKTALNPLRENPCQFVDKTLPLQSSIFNPKSRIQNSKSLHPSSSKSKAGWLDSEMAK
>NC_008639.1|WP_041467348.1|2392524_2392800_-|CRISPR-associated-endonuclease-Cas2
MFMLVSYDICDIKRLPRVAKLMEGYGVRVQYSVFECSLTQRQLMELQRRLKRLIKPEVDSVRFYPLCESCRDEIVILGQGTVSRDEPYYIA
>NC_008639.1|WP_011745875.1|2392803_2393847_-|CRISPR-associated-endonuclease-Cas1
MSEASLFLRTLYIQEQGSMLRVENGCFRVTCGHDDDVAELLEVQSIKVGQIVLFGACMITPAAIRHCLMNRIPVVLLSQHGEYFTRLESTDDVNIDLERLQFQRSAEESFPLECSRTIVRAKLHNSGVLLRRHAESSGSEALRHAATQLRQLEEHVDRADSIDAVRGYEGSGAATYFGVFEDFFDTGGFIFRERVKRPPTDPVNAMLSFGYSLLFNNIFSMARLHRLHPYVGFLHADKPAHPALVSDLIEEFRTLVDGLVIALINKRLISPEEFTVARHDDGKPKGCYLSDGARKTFLREFENLMHRTTTHPATGYEVTCRRCLDLQVGEFALYLKGEKPYTPYLRR

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Crispr_ID: NC_008639_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008639_5

2383057-2384197

TypeIII

Consensus_repeat	Method
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CRISPRCasFinder
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CRT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	PILER-CR

15 spacers

cas2,cas1,csx15,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6

The CRISPR arrays of NC_008639_5

>merge|NC_008639|5|2383057-2384197|CRISPRCasFinder,CRT,PILER-CR
TATATCACCCTCTATGAGTGCAATAAGATATAAAGAAAAAACAGAGGCTTAACGCCAACGTGCTGGATTATCTGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTTGACGTTGGGCGTAATGGTATTTGTCATGCCATCATTCCTGAAAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGCGTTGACTACGACGCTCACATTGCAAAGAACGGAAAGAAGGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTTTGGATACGTGAGGGCGATGAATATCGCCCACCAAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGGAAACCTCATGGAGGACAGAGAAAAAGAAAAAATACGTTTGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGAACGGAATCCGGAAAACCATGTACGACGGCGGAAACTGACAATGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGCGACACTATCCCCAAAGGAGTCCGGAGTACCGGATGGTGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTAATAACAACAATAAAAAAGGAGTAGTCGAATGCGTAAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTCCCCGAACACAAATTGCAGAAGGAATTGATCATTTATGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGAGGCGACAGCAACTGGTGGCAACGCCAGTGCAAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGAAAATGTACATTGACGGTAAAGATGATAAACGTTAAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTGTCAACCTTGTTAGCTTGCAGTAGAGAATACGAGACAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTTGGAAAAAAGTTTTCAGTTTTTGGGGAGCATTCCTCAATATTCTGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGCAGATGAAGCTCGAAATCCACCATCCCAACAAGAAAAGTTTCAATCCTCTATGAGTGCAATAAGATATAAAGTCGGCAACAATGGAGGTGATTATGGGTAAGTATTATGTTTCAATCCTCTATGAGTGCAATAAGATATAAAG

>NC_008639|5|6|2383057-2384197|CRISPRCasFinder
TATATCACCCTCTATGAGTGCAATAAGATATAAAG	AAAAAACAGAGGCTTAACGCCAACGTGCTGGATTATCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTGACGTTGGGCGTAATGGTATTTGTCATGCCATCATTCCTGAAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CGTTGACTACGACGCTCACATTGCAAAGAACGGAAAGAAG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTGGATACGTGAGGGCGATGAATATCGCCCACCAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GAAACCTCATGGAGGACAGAGAAAAAGAAAAAATACGTTT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AACGGAATCCGGAAAACCATGTACGACGGCGGAAACTGACAAT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CGACACTATCCCCAAAGGAGTCCGGAGTACCGGATGGT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TAATAACAACAATAAAAAAGGAGTAGTCGAATGCGTAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCCCCGAACACAAATTGCAGAAGGAATTGATCATTTAT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AGGCGACAGCAACTGGTGGCAACGCCAGTGCAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AAAATGTACATTGACGGTAAAGATGATAAACGTTAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGTCAACCTTGTTAGCTTGCAGTAGAGAATACGAGACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTGGAAAAAAGTTTTCAGTTTTTGGGGAGCATTCCTCAATATTCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CAGATGAAGCTCGAAATCCACCATCCCAACAAGAAAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCGGCAACAATGGAGGTGATTATGGGTAAGTATTAT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG

>NC_008639|5|4|2383057-2384197|CRT
TATATCACCCTCTATGAGTGCAATAAGATATAAAG	AAAAAACAGAGGCTTAACGCCAACGTGCTGGATTATCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTGACGTTGGGCGTAATGGTATTTGTCATGCCATCATTCCTGAAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CGTTGACTACGACGCTCACATTGCAAAGAACGGAAAGAAG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTGGATACGTGAGGGCGATGAATATCGCCCACCAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GAAACCTCATGGAGGACAGAGAAAAAGAAAAAATACGTTT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AACGGAATCCGGAAAACCATGTACGACGGCGGAAACTGACAAT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CGACACTATCCCCAAAGGAGTCCGGAGTACCGGATGGT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TAATAACAACAATAAAAAAGGAGTAGTCGAATGCGTAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCCCCGAACACAAATTGCAGAAGGAATTGATCATTTAT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AGGCGACAGCAACTGGTGGCAACGCCAGTGCAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AAAATGTACATTGACGGTAAAGATGATAAACGTTAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGTCAACCTTGTTAGCTTGCAGTAGAGAATACGAGACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTGGAAAAAAGTTTTCAGTTTTTGGGGAGCATTCCTCAATATTCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CAGATGAAGCTCGAAATCCACCATCCCAACAAGAAAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCGGCAACAATGGAGGTGATTATGGGTAAGTATTAT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG

>NC_008639|5|6|2383130-2384197|PILER-CR
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTGACGTTGGGCGTAATGGTATTTGTCATGCCATCATTCCTGAAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CGTTGACTACGACGCTCACATTGCAAAGAACGGAAAGAAG
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTTGGATACGTGAGGGCGATGAATATCGCCCACCAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	GAAACCTCATGGAGGACAGAGAAAAAGAAAAAATACGTTT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AACGGAATCCGGAAAACCATGTACGACGGCGGAAACTGACAAT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CGACACTATCCCCAAAGGAGTCCGGAGTACCGGATGGT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TAATAACAACAATAAAAAAGGAGTAGTCGAATGCGTAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCCCCGAACACAAATTGCAGAAGGAATTGATCATTTAT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AGGCGACAGCAACTGGTGGCAACGCCAGTGCAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	AAAATGTACATTGACGGTAAAGATGATAAACGTTAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TGTCAACCTTGTTAGCTTGCAGTAGAGAATACGAGACA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TTGGAAAAAAGTTTTCAGTTTTTGGGGAGCATTCCTCAATATTCT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	CAGATGAAGCTCGAAATCCACCATCCCAACAAGAAAA
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG	TCGGCAACAATGGAGGTGATTATGGGTAAGTATTAT
GTTTCAATCCTCTATGAGTGCAATAAGATATAAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008639.1\|WP_011745867.1\|2376348_2377212_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378236
NC_008639.1\|WP_011745861.1\|2369101_2370166_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|380071
NC_008639.1\|WP_011745863.1\|2371046_2371523_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NC_008639.1\|WP_041467710.1\|2389058_2389454_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319947
NC_008639.1\|WP_011745870.1\|2384619_2384907_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745869.1\|2381638_2381923_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_008639.1\|WP_011745872.1\|2386426_2388055_-\|RelA/SpoT-domain-containing-protein	unknown	unknown	gnl\|CDD\|214934
NC_008639.1\|WP_011745862.1\|2370176_2371034_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_008639.1\|WP_011745866.1\|2375737_2376310_-\|hypothetical-protein	csx15	cd09766_csx15_CAS-I:CAS-III	gnl\|CDD\|187735
NC_008639.1\|WP_011745864.1\|2371522_2373811_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
NC_008639.1\|WP_041467343.1\|2367138_2369109_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|273863
NC_008639.1\|WP_011745865.1\|2374659_2375253_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_041467347.1\|2390102_2390564_+\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_041467348.1\|2392524_2392800_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_008639.1\|WP_011745876.1\|2393839_2394841_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	gnl\|CDD\|187890
NC_008639.1\|WP_041467349.1\|2395244_2395529_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745868.1\|2379402_2381598_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_008639.1\|WP_011745875.1\|2392803_2393847_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_008639.1\|WP_011745871.1\|2384903_2385551_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	unknown	unknown	gnl\|CDD\|378065
NC_008639.1\|WP_190271880.1\|2389692_2389830_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008639.1\|WP_011745864.1\|2371522_2373811_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	1.8e-87	289.1	0.1
NC_008639.1\|WP_041467343.1\|2367138_2369109_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	4.8e-19	63.5	5.9
NC_008639.1\|WP_011745875.1\|2392803_2393847_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	7.6e-95	312.3	0.0
NC_008639.1\|WP_011745868.1\|2379402_2381598_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	3.2e-90	297.1	0.1
NC_008639.1\|WP_041467348.1\|2392524_2392800_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.6e-30	99.9	0.1
NC_008639.1\|WP_011745861.1\|2369101_2370166_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	4.8e-31	102.8	0.0
NC_008639.1\|WP_011745863.1\|2371046_2371523_-\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	4.3e-18	60.6	0.8
NC_008639.1\|WP_011745876.1\|2393839_2394841_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	1.4e-100	331.4	0.5
NC_008639.1\|WP_011745869.1\|2381638_2381923_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	1.6e-26	87.1	0.2
NC_008639.1\|WP_011745862.1\|2370176_2371034_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	2.4e-60	198.7	0.5
NC_008639.1\|WP_011745866.1\|2375737_2376310_-\|hypothetical-protein	csx15	cd09766_csx15_CAS-I:CAS-III	2.8e-39	127.7	0.1

Protein	Function_ID	Function_description	E-value
NC_008639.1\|WP_011745867.1\|2376348_2377212_-\|hypothetical-protein	gnl\|CDD\|378236	pfam09670, Cas_Cas02710, CRISPR-associated protein (Cas_Cas02710). Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	0.0031769
NC_008639.1\|WP_011745861.1\|2369101_2370166_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	3.60031e-33
NC_008639.1\|WP_011745863.1\|2371046_2371523_-\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	3.71242e-23
NC_008639.1\|WP_041467710.1\|2389058_2389454_-\|VOC-family-protein	gnl\|CDD\|319947	cd08359, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.33022e-34
NC_008639.1\|WP_011745869.1\|2381638_2381923_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.6855e-28
NC_008639.1\|WP_011745872.1\|2386426_2388055_-\|RelA/SpoT-domain-containing-protein	gnl\|CDD\|214934	smart00954, RelA_SpoT, Region found in RelA / SpoT proteins. The functions of Escherichia coli RelA and SpoT differ somewhat. RelA produces pppGpp (or ppGpp) from ATP and GTP (or GDP). SpoT degrades ppGpp, but may also act as a secondary ppGpp synthetase. The two proteins are strongly similar. In many species, a single homolog to SpoT and RelA appears reponsible for both ppGpp synthesis and ppGpp degradation. (p)ppGpp is a regulatory metabolite of the stringent response, but appears also to be involved in antibiotic biosynthesis in some species.	3.27023e-20
NC_008639.1\|WP_011745862.1\|2370176_2371034_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	5.65062e-64
NC_008639.1\|WP_011745866.1\|2375737_2376310_-\|hypothetical-protein	gnl\|CDD\|187735	cd09766, Csx15_I-U, CRISPR/Cas system-associated protein Csx15. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small protein loosely associated with CRISPR/Cas systems; some are fused to AAA ATPase domain, also known as TTE2665 family.	2.04612e-42
NC_008639.1\|WP_011745864.1\|2371522_2373811_-\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	1.03012e-88
NC_008639.1\|WP_041467343.1\|2367138_2369109_-\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|273863	TIGR01899, cas_TM1807_csm5, CRISPR type III-A/MTUBE-associated RAMP protein Csm5. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm5, for CRISPR/cas Subtype Mtube, protein 5.	7.22703e-05
NC_008639.1\|WP_011745868.1\|2379402_2381598_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.83526e-106
NC_008639.1\|WP_041467348.1\|2392524_2392800_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.02121e-32
NC_008639.1\|WP_011745876.1\|2393839_2394841_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|187890	cd09760, Cas6_III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex.	1.03279e-10
NC_008639.1\|WP_011745875.1\|2392803_2393847_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.13541e-107
NC_008639.1\|WP_011745871.1\|2384903_2385551_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	gnl\|CDD\|378065	pfam08843, AbiEii, Nucleotidyl transferase AbiEii toxin, Type IV TA system. This family was recently identified as belonging to the nucleotidyltransferase superfamily. AbiEii is the cognate toxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	9.75601e-08

>NC_008639.1|WP_011745869.1|2381638_2381923_-|CRISPR-associated-endonuclease-Cas2
MQFILVTYDIENDRRRTKIHKVLEGYGISVQYSVFECFLSDEDYAGLRIRLQKLMDPKHPLDSIRYYHLCRGCVEKVDVDGNRSFEIASPFIIT
>NC_008639.1|WP_011745868.1|2379402_2381598_-|CRISPR-associated-endonuclease-Cas1
MGWLYNQMAMPETIFQAWYKVASNDGRPGWDNTSIQDYSLRLEENLKSLSHALLTGTYRQSPLLKLVMLKPDGKERVLLIPGVIDRVAQTAASIVLSPIIEAELGNCTFAYRPGISREGAAREIDRLHREGYQWVLDADIRNFFDNVRHDLLFQRLVELVDDKEMISLLHRWLTAEIVDGLNPRTRNTMGLPQGCPISPALANLYLDRFDETMEQQGFKLVRFADDYLVLCKTRPKAEAALKLSESALAELKLELHSDKTRITTFAEGFKYLGYLFIRSLVIPTKMHPEEWYDKLGKFRLRKKSVHALPADPETMTGETSQFELETDQGEKIELSKEELLQTEFGKKLLESLDKKQLNVDEFLEKISRQDEERQKEKREALKKLYSPFLNTLYLQEQGSLMRKDGERFSIEKDGSVINEVIVRRIEQVVIFGNVALTTPVMQYCLQNEIPVTFLSQHGKYFGRLEATTADNAEMQRFHFLRSIDEPFALETARSIVAAKISNSKTMIRRRKTVVQDRDSTLQNKMAYNLDIMADLALKAEASTDIDALRGIEGKASALYFECYGMLFSKNLPFHTRSFLRVRRPPTDPVNSLLSFGYTMLHTNIFSMVQASGLNPYIGFLHAERKGNPALVNDLVEEFRTIVDSLVLYTLNRGLLQEKDFYYRKDEPGCFLSNDARKRFLNIFETRMWQESRDGCTGKTLNFRRHIEKQVRIMREVIAGTRTQYDPYKLPV
>NC_008639.1|WP_011745867.1|2376348_2377212_-|hypothetical-protein
MSTNPIQQKMRVQSLRRFAEGIVGRKNFGWWSLLYAALFFVVAGWFADGLAEFVDYVFSGQKRWILNYKLIVSAGLLFLFGWSIRNIAHDDHDEIAVNRDQPKPVRVLGLFLSNFLVRVDQTSHSGNSGDGFNKSALERAVSDSTFNRTMLLDTTWEMPFRAIEYHASSLERIELFTSSGGKCSSAESGLFIRLVAVLYPDVSVTEQIVDFEDLEVVFKAVEKLYADAEASGLKAQDVLVDITGGQKPNSIAAAIATLAVGRQFQYISTGDKVVRSYDVGYFQEDLS
>NC_008639.1|WP_011745866.1|2375737_2376310_-|hypothetical-protein
MNEFFTQNNLLVVFWYTAGIVSIIELLEYLVTRNIPWLLRLIRGLWRGVARRFRGDISQGARQLIINFSGHPVLPGQQQDIGQMMHWSSSEVINVSIGNVPEDHNFVPSIEKSVEKIPLSPEEWQSIPVVVIPSGYSQIWSVVMAELHGRLGYFPDVVRLRFSSSISNEKFEVAEIMNLREVRHNSRDKR
>NC_008639.1|WP_011745865.1|2374659_2375253_-|hypothetical-protein
MPLPDDKSFSQLKKSEFHLWFKKAEKAVKEVEYIHAELTMPAVNELRYAGYHVSNYLEDTELLDELNRAVGHCKRAIYDAYEASILYNIKEFRAFKNDYGTVVISEVLADYSDLHYRVTNILEFLRSIDKETKDQHYAACKEHHQELKDIIIKLDSARDELNKKIRIERKKSFFAIAGIALAVLSAVIAFLAYLGCH
>NC_008639.1|WP_011745864.1|2371522_2373811_-|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MTTSITGNDIIKLGFDLLREGTLSIVDIVDAFKLAGIQSTELKLSSLKSPFGGDRFFEPKQLSATEINYPVYDRVTDFSEIIPQDDDQGLTALERLGSFVATDADEKYSVFDLFKTVAAIQDCLRNPEEDKPFLLVSADFSGIQDTVYTISSKGALKTLRARSFMLELLTEHIIYEILSEVESERYAVVFSGGGGFGLLLPNSEESIRTINDYRTRINEWAFDEFSGRFFIAMDALPFGREELLSGMSFRNIRQTQADNLDRLKRRKFIDQFEQLFTPSMPKQLTVNTECQITRRDDMPDEFMFDLETETRMSLVPAKEREDDKWIWVSESCYHQFWIGDKLATAQSVVRSQKTPEGKEPYFKYPDATWSKENKSWVYYQIDDQQTKSADCWFMNDWTAGQPILYANYVRKHGELSEYAKKLENESLKEENPTAKPNHTATFQGLAASSCGADLIGALRMDVDDMGNLFSSIGSLTELSAKSRMLNLFFKVYLNQICAANLGGGFSYTDIAKKNYSVKNSHGDIGRNVSVIYAGGDDLFILGAWDETTELAFDIQRCFSLFTGETLNKEKKTVVEGLGISGGLTLHQPKFPLYQMAQKSGEAEHGAKNDIEIQNAEIEKNRISLFFDDSKRQCRLKIQEPYRYMLSMKWDLSSAFLLPLMKTYRECGNVAFQDGRMVLEIEKFSYQTIEKWFAVIEKYQESSMLYLPTMARVMKQVEENPRMDASLFKTLLGFLYTNDESKKNWISHLHVALNWLTYLRRKN
>NC_008639.1|WP_011745863.1|2371046_2371523_-|type-III-A-CRISPR-associated-protein-Csm2
MGYDFTEIYQINKQFDVDVHQIVSRIEGFGSFSSISEYELENLPKYAAVIAKAMKEKKKPVTPTQLRRFYTYVKSIDLANKQTKEDEQNFKDKYKLKFILPKIAGSSECESLEDLYKVLNACVNGDKIITVKDLRLFMEFFEAILDYHSTFKTQKKDN
>NC_008639.1|WP_011745862.1|2370176_2371034_-|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MADIERQIKLLGYIKITGIIEALTGLHIGGTADSIDKGGIDNPVIKNPVTNEPYIPGSSFRGRMRSLLEKKTAEYLSPMTGNKEIWMEIYKAEDEKYNNNKAQSTIDAMNSEVCRVFGNSASYESVPSVLIVRDALYTEKTRESYMQGGKGGLPITEAKMEIAVDRITAHALPRTIERVPAGAKFAFEIVYKIQSTSFICVIDEKGKPKEVKSYMADDKVIEKDIENILWALKQIEEHDGLGGNTSRGHGQVKFSIDPIKYEVFEDVSKQKIEKAIKNIKTTKEA
>NC_008639.1|WP_011745861.1|2369101_2370166_-|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MNTYIVHLYFKNALHVGAANSGIGIEATQDFIHSDTLWAAIANHWAILGKVGDISFDDFLNGFRTKHDDGIRHKEEPLFRISSAFPLTDNGRMYWLPKPLSVPMAFSKRNIEDRENQRKEYGKKVKQEKFIPLKVFKEWMNFEKNASDVGGAKREGISSGQMRPHATIDRISMRAQLFHSGITYFDKFAVRVGLYFLIQCGKTTKTALEKVFEVIYEAGAIGGNRNIGLGSLFEKPSLTEASEFADLFNTENTNAYCLLSLCYLSDGEIPNAETAVAYNHLLRKGWTGSLSVSLQRKRKTVYMFAEGSVFQTKLNGCLADITPDKIITPEWYGHHDVYRYGYALSVPIKIDLDD
>NC_008639.1|WP_041467343.1|2367138_2369109_-|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MTEHMESKIIELETLTSLFIKGKEENYGEGFIRIGNTLYFIDNDNLCEFIYKNTYDKDGSRIPNRPDYVEWYSYFISRQRGDDIVTHYKGFAKVFGLDDVNNERDIPEGYKEKSIQFFLSKTRLLQGNNDTQKQVLTEYKIGKGITLLEASTRNGNRFIQNGNKRHYVPGSSLKGAIRNAVLWKILTESSIQAWFLLFLTYHLPVSDFLKKIDENDYEEGEKIISKNAVFQNMNLIRNGHIDRKETKKLKKKYSEHLSGIQDATNSTLESKCFTGKIPYIPISDSDKIDQKKYLQSYNDRWNAANDTLRDFFRLVKVSDGNFVDDFELKGKIAKAVCRDIFGTPPKNKTYQKKFDIKLECAPKTVKVQFKISIDTELVRAFFPYRIPVYLQSVNGLMNVVDEFYREVAKFEALNYYNGVISIPDDLNSNDNRKAKLKVNTEVVYKLYNTIFGLEKNETLFRTGWGGGFMSKTQFLHMDMTDRVRVRDMVHYNGSPLAPKSRCLIIEGQNATEPLGWCKLRVLGDTKDLALPSIDAVKISTDILTEQPRQRGQQRQENRQNKERPVTEKEIHKSKAEAKAILKLVEKQTNLTTQVTYMKGQVVLAKVDECKPFESIKITIGNQSVCVVSGFIKQKGEEVKIKITKIENGKILEAKLL
>NC_008639.1|WP_011745870.1|2384619_2384907_-|hypothetical-protein
MKTLPVTPEMLQVARRVVWFREPEDELADPVHFLAHVMTYGTVDDLQMLQGIAGKNEFSEVLENPPPGVFDARSWAYWNLKCGRQPAPPLPIRIL
>NC_008639.1|WP_011745871.1|2384903_2385551_-|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein
MLPPSQLRLWPELDATPETFTLYGGTALALRFGHRVSVDFDFFSNKPFDPDELVDTLFYLKGAERLQVGPNTLTCRVDRGGPVLLSFFGGLGLGQVEAPDQAQGSTLFVASLLDIAGTKAAVVQKRAEVKDYLDMDALLQHGIDLPTVLAAGQVIYGCSFNPMITLKALSFFDDIPALPTDIRDRLCHAVDSVDPINLPVLKPYAERKIENGYNS
>NC_008639.1|WP_011745872.1|2386426_2388055_-|RelA/SpoT-domain-containing-protein
MKSKVSFEDACLHLKSIAGPTKMQLLALEDNCLNNNAVSKIYLTKYRIKKQESVYLKTKRKNKSLDEINDYGGLRLLCLFEDDIFDVHNDFVRMLHAKHYELKCCSAYNWNVKSIDKLRGEIDRYFDKNKYVFEKIKKTSGYKSVHYVVKQSGLDAEWIEVQLRTLVQDVWGELEHSISYKKGGIHPHIKKSFSLLSKELINIESLLSYLKEVNQKEIAGEEYYNKLVTPKYVFKYESQILPPCFEINVNLKVCYKQYWEIIESFETTSISHNWINQARAKLTEFNRNLTIDQLDENPELEYWIKMENAFLLFCDLKHEDSLKEYEKLLTKFGNRYCVHFRAGELYFILGHIEKALSSFDKAEDLIVVTEEIDHVNHYRIKTRLAYYYWSLGEEYIDISITEIKEAEEIFSKNKQLFDEAQYEQLVNNICWYKLEKYIIAVKKAESEETEENIRNADLAFEDVSSSYVVIDTLLKTNYISSHLLDTAAWYCYWVYKKTNDRAYLSKARDYALSINEKVKLTSYPFKSMKTHMNHIQAIMSAK
>NC_008639.1|WP_041467710.1|2389058_2389454_-|VOC-family-protein
MSVNAISTCITTEKVAESREFYVGHFNAEVTFDCGWYVNIRFAECSATLQFMAPREGQSPCNPAGLMYNISVPDVDEEYIRLTGEGLIPVMPLEDHPWGDRGFAVLDPNGVILYLFSERPASDEFKKYFLP
>NC_008639.1|WP_190271880.1|2389692_2389830_-|hypothetical-protein
MKIEEEEFCPRIDTNFHEEDLRLFCYFAISLSSYPAIQLSSLAFG
>NC_008639.1|WP_041467347.1|2390102_2390564_+|hypothetical-protein
MKIRVNSWTKLFLVQSSIQNPESKIQNLFTPLHPKARLDVGSAKRKQQTALISFRENSCQFVDKTLPLQSSIQNPKLKISSPLFIQKQGWIARWRNSKTALNPLRENPCQFVDKTLPLQSSIFNPKSRIQNSKSLHPSSSKSKAGWLDSEMAK
>NC_008639.1|WP_041467348.1|2392524_2392800_-|CRISPR-associated-endonuclease-Cas2
MFMLVSYDICDIKRLPRVAKLMEGYGVRVQYSVFECSLTQRQLMELQRRLKRLIKPEVDSVRFYPLCESCRDEIVILGQGTVSRDEPYYIA
>NC_008639.1|WP_011745875.1|2392803_2393847_-|CRISPR-associated-endonuclease-Cas1
MSEASLFLRTLYIQEQGSMLRVENGCFRVTCGHDDDVAELLEVQSIKVGQIVLFGACMITPAAIRHCLMNRIPVVLLSQHGEYFTRLESTDDVNIDLERLQFQRSAEESFPLECSRTIVRAKLHNSGVLLRRHAESSGSEALRHAATQLRQLEEHVDRADSIDAVRGYEGSGAATYFGVFEDFFDTGGFIFRERVKRPPTDPVNAMLSFGYSLLFNNIFSMARLHRLHPYVGFLHADKPAHPALVSDLIEEFRTLVDGLVIALINKRLISPEEFTVARHDDGKPKGCYLSDGARKTFLREFENLMHRTTTHPATGYEVTCRRCLDLQVGEFALYLKGEKPYTPYLRR
>NC_008639.1|WP_011745876.1|2393839_2394841_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MYTSLFPLRIARFRCTIEPLELVQLPDYKGSALRGGFGHAFRRATCLSRDRECESCMLKSACAYYTVFESRVSRQTADRLRIGADAPHPFLLEPPMTGQHCFEPGQKISYGLTLFGSAIEKLPFFIYAFMILGENLGLGKGRGRFRLLAVEDEGGRNLYHDGHLSGGFVILSARDILESTSTDDRPLALRFETPLRMKTAWQRKEQELLTGIGHEDDFRLLLKSLYHRAFVLTQLYGDLPEPASYNSRNLPLVNGDVHLGSAETRWLDWTRYSQRHQQHMQLGGILGSVTFTGKTGQYLPLFRLGEYLHIGKGTTFGLGKYRMVEPVPEQTGE
>NC_008639.1|WP_041467349.1|2395244_2395529_-|hypothetical-protein
MPTNYTNLHEKRIGSWFSLASPIKTTAGFSIKRRMGMKMGSFAHELREFARKGIKALLLFRHLAIQLSSLAFGLKRGGGDFEFWIMNCGLKIED

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Crispr_ID: NC_008639_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008639_6

2390660-2392257

TypeIII

Consensus_repeat	Method
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CRISPRCasFinder
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CRT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	PILER-CR

20 spacers

cas2,cas1,csx15,cas6

The CRISPR arrays of NC_008639_6

>merge|NC_008639|6|2390660-2392257|CRISPRCasFinder,CRT,PILER-CR
TCTCCTAACCCTCTTAATACGTCAGGTCTTAATCAACGTGGACCGTTACGCGATGCTTATTGTTGAAAGGTACATGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACTTGAAGGGAGCAGGGCCAACAGCTGGCGCAGATTGTATGGTGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACACGGGTTCACGGAGCGGCATGGGGTCGCGATTTAAAATAGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACAATGAAATTTACTCAATGCACTTTGTCAGATGCCAAAGGCAAGGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACACAAACCCAAGACAGGCCCTGATGGAAAGTGAGCCAGTTTATTAAGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACGTAAAAGGCCCTCAACACTTCAATCAGGTCTCGGGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACTTGATCGGGTGCATGAAAATAACATCCGGTTCATCCCCCCAGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACGCTCGATTGCATAACGAACAGATGGCGGATTTGGCGATAATTTGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACCGGACGAAAATGCCCACCGGACGATATGGGCGGATTACTTGAAGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACAACATGAATTTTTTGACAATTCATACTTTCTGGTATGATATTGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACCAAGCTGGCAGGACGCCTTGGCGATATGCGACGAGGTCAACGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACAAGGCCATCAGCACTTCGATCAGATTGTAGCGGCCTACAAGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACGAAGCAAGGAATTGACACAACAAGAAACGTTACTGCTGAAGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACCCGTTATGTGCTATGGCAAGGCTGCCGGAACGATAGGTTAAAGAGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACTTTTGAAATTCTACCCGAAGAAGAAGGCAGACAAAAGTACCTCATTGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACAAATGAATAACTTTGTGAAAAGAGTTATGGAAATTCCTGTGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACTGTTATGGGCTCGGGTCTCAACATCTCAGGCGGTACTTTCGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACAACACACAATACAGTCGCATCGTCTCACAGCGCCTAAGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACGTTTCAGAATGCGGCGAACGCTGAAGAGAAGACGATTTCGTTTTGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAACTCACAGTTCTTCGCACCGAAGAGAGCCGCGGCAGATGCCCGTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC

>NC_008639|6|7|2390660-2392257|CRISPRCasFinder
TCTCCTAACCCTCTTAATACGTCAGGTCTTAATCAAC	GTGGACCGTTACGCGATGCTTATTGTTGAAAGGTACAT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TTGAAGGGAGCAGGGCCAACAGCTGGCGCAGATTGTATGGT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	ACGGGTTCACGGAGCGGCATGGGGTCGCGATTTAAAATA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AATGAAATTTACTCAATGCACTTTGTCAGATGCCAAAGGCAAG
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	ACAAACCCAAGACAGGCCCTGATGGAAAGTGAGCCAGTTTATTAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GTAAAAGGCCCTCAACACTTCAATCAGGTCTCGG
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TTGATCGGGTGCATGAAAATAACATCCGGTTCATCCCCCCA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GCTCGATTGCATAACGAACAGATGGCGGATTTGGCGATAATTT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CGGACGAAAATGCCCACCGGACGATATGGGCGGATTACTTGAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AACATGAATTTTTTGACAATTCATACTTTCTGGTATGATATT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CAAGCTGGCAGGACGCCTTGGCGATATGCGACGAGGTCAAC
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AAGGCCATCAGCACTTCGATCAGATTGTAGCGGCCTACAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GAAGCAAGGAATTGACACAACAAGAAACGTTACTGCTGAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CCGTTATGTGCTATGGCAAGGCTGCCGGAACGATAGGTTAAAGA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TTTTGAAATTCTACCCGAAGAAGAAGGCAGACAAAAGTACCTCATT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AAATGAATAACTTTGTGAAAAGAGTTATGGAAATTCCTGT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TGTTATGGGCTCGGGTCTCAACATCTCAGGCGGTACTTTC
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AACACACAATACAGTCGCATCGTCTCACAGCGCCTAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GTTTCAGAATGCGGCGAACGCTGAAGAGAAGACGATTTCGTTTT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TCACAGTTCTTCGCACCGAAGAGAGCCGCGGCAGATGCCC
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC

>NC_008639|6|5|2390660-2392257|CRT
TCTCCTAACCCTCTTAATACGTCAGGTCTTAATCAAC	GTGGACCGTTACGCGATGCTTATTGTTGAAAGGTACAT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TTGAAGGGAGCAGGGCCAACAGCTGGCGCAGATTGTATGGT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	ACGGGTTCACGGAGCGGCATGGGGTCGCGATTTAAAATA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AATGAAATTTACTCAATGCACTTTGTCAGATGCCAAAGGCAAG
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	ACAAACCCAAGACAGGCCCTGATGGAAAGTGAGCCAGTTTATTAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GTAAAAGGCCCTCAACACTTCAATCAGGTCTCGG
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TTGATCGGGTGCATGAAAATAACATCCGGTTCATCCCCCCA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GCTCGATTGCATAACGAACAGATGGCGGATTTGGCGATAATTT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CGGACGAAAATGCCCACCGGACGATATGGGCGGATTACTTGAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AACATGAATTTTTTGACAATTCATACTTTCTGGTATGATATT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CAAGCTGGCAGGACGCCTTGGCGATATGCGACGAGGTCAAC
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AAGGCCATCAGCACTTCGATCAGATTGTAGCGGCCTACAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GAAGCAAGGAATTGACACAACAAGAAACGTTACTGCTGAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CCGTTATGTGCTATGGCAAGGCTGCCGGAACGATAGGTTAAAGA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TTTTGAAATTCTACCCGAAGAAGAAGGCAGACAAAAGTACCTCATT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AAATGAATAACTTTGTGAAAAGAGTTATGGAAATTCCTGT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TGTTATGGGCTCGGGTCTCAACATCTCAGGCGGTACTTTC
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AACACACAATACAGTCGCATCGTCTCACAGCGCCTAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GTTTCAGAATGCGGCGAACGCTGAAGAGAAGACGATTTCGTTTT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TCACAGTTCTTCGCACCGAAGAGAGCCGCGGCAGATGCCC
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC

>NC_008639|6|7|2390735-2392257|PILER-CR
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TTGAAGGGAGCAGGGCCAACAGCTGGCGCAGATTGTATGGT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	ACGGGTTCACGGAGCGGCATGGGGTCGCGATTTAAAATA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AATGAAATTTACTCAATGCACTTTGTCAGATGCCAAAGGCAAG
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	ACAAACCCAAGACAGGCCCTGATGGAAAGTGAGCCAGTTTATTAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GTAAAAGGCCCTCAACACTTCAATCAGGTCTCGG
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TTGATCGGGTGCATGAAAATAACATCCGGTTCATCCCCCCA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GCTCGATTGCATAACGAACAGATGGCGGATTTGGCGATAATTT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CGGACGAAAATGCCCACCGGACGATATGGGCGGATTACTTGAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AACATGAATTTTTTGACAATTCATACTTTCTGGTATGATATT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CAAGCTGGCAGGACGCCTTGGCGATATGCGACGAGGTCAAC
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AAGGCCATCAGCACTTCGATCAGATTGTAGCGGCCTACAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GAAGCAAGGAATTGACACAACAAGAAACGTTACTGCTGAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	CCGTTATGTGCTATGGCAAGGCTGCCGGAACGATAGGTTAAAGA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TTTTGAAATTCTACCCGAAGAAGAAGGCAGACAAAAGTACCTCATT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AAATGAATAACTTTGTGAAAAGAGTTATGGAAATTCCTGT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TGTTATGGGCTCGGGTCTCAACATCTCAGGCGGTACTTTC
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	AACACACAATACAGTCGCATCGTCTCACAGCGCCTAA
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	GTTTCAGAATGCGGCGAACGCTGAAGAGAAGACGATTTCGTTTT
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC	TCACAGTTCTTCGCACCGAAGAGAGCCGCGGCAGATGCCC
GTTTCAATCCCTCTTAATACGTCAGGTCTTAATCAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008639.1\|WP_011745867.1\|2376348_2377212_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378236
NC_008639.1\|WP_011745881.1\|2401230_2401506_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_190271881.1\|2401509_2401656_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|133390
NC_008639.1\|WP_011745878.1\|2396879_2397422_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745877.1\|2396579_2396849_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_041467710.1\|2389058_2389454_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319947
NC_008639.1\|WP_011745870.1\|2384619_2384907_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745869.1\|2381638_2381923_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_008639.1\|WP_011745872.1\|2386426_2388055_-\|RelA/SpoT-domain-containing-protein	unknown	unknown	gnl\|CDD\|214934
NC_008639.1\|WP_011745880.1\|2399323_2401234_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745866.1\|2375737_2376310_-\|hypothetical-protein	csx15	cd09766_csx15_CAS-I:CAS-III	gnl\|CDD\|187735
NC_008639.1\|WP_011745875.1\|2392803_2393847_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_008639.1\|WP_011745868.1\|2379402_2381598_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_008639.1\|WP_190271880.1\|2389692_2389830_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_041467348.1\|2392524_2392800_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_008639.1\|WP_150081108.1\|2398448_2399168_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_041467349.1\|2395244_2395529_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745876.1\|2393839_2394841_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	gnl\|CDD\|187890
NC_008639.1\|WP_011745871.1\|2384903_2385551_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	unknown	unknown	gnl\|CDD\|378065
NC_008639.1\|WP_041467347.1\|2390102_2390564_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008639.1\|WP_011745875.1\|2392803_2393847_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.13541e-107
NC_008639.1\|WP_011745867.1\|2376348_2377212_-\|hypothetical-protein	gnl\|CDD\|378236	pfam09670, Cas_Cas02710, CRISPR-associated protein (Cas_Cas02710). Members of this family are found, exclusively in the vicinity of CRISPR repeats and other CRISPR-associated (cas) genes, in Methanothermobacter thermautotrophicus (Methanobacterium thermoformicicum), Thermus thermophilus (Deinococcus-Thermus), Chloroflexus aurantiacus (Chloroflexi), and Thermomicrobium roseum (Thermomicrobia).	0.0031769
NC_008639.1\|WP_011745868.1\|2379402_2381598_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	5.83526e-106
NC_008639.1\|WP_190271881.1\|2401509_2401656_-\|hypothetical-protein	gnl\|CDD\|133390	cd04762, HTH_MerR-trunc, Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins. Proteins in this family mostly have a truncated helix-turn-helix (HTH) MerR-like domain. They lack a portion of the C-terminal region, called Wing 2 and the long dimerization helix that is typically present in MerR-like proteins. These truncated domains are found in response regulator receiver (REC) domain proteins (i.e., CheY), cytosine-C5 specific DNA methylases, IS607 transposase-like proteins, and RacA, a bacterial protein that anchors chromosomes to cell poles.	0.00441254
NC_008639.1\|WP_041467348.1\|2392524_2392800_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.02121e-32
NC_008639.1\|WP_011745876.1\|2393839_2394841_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|187890	cd09760, Cas6_III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex.	1.03279e-10
NC_008639.1\|WP_041467710.1\|2389058_2389454_-\|VOC-family-protein	gnl\|CDD\|319947	cd08359, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.33022e-34
NC_008639.1\|WP_011745872.1\|2386426_2388055_-\|RelA/SpoT-domain-containing-protein	gnl\|CDD\|214934	smart00954, RelA_SpoT, Region found in RelA / SpoT proteins. The functions of Escherichia coli RelA and SpoT differ somewhat. RelA produces pppGpp (or ppGpp) from ATP and GTP (or GDP). SpoT degrades ppGpp, but may also act as a secondary ppGpp synthetase. The two proteins are strongly similar. In many species, a single homolog to SpoT and RelA appears reponsible for both ppGpp synthesis and ppGpp degradation. (p)ppGpp is a regulatory metabolite of the stringent response, but appears also to be involved in antibiotic biosynthesis in some species.	3.27023e-20
NC_008639.1\|WP_011745869.1\|2381638_2381923_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.6855e-28
NC_008639.1\|WP_011745871.1\|2384903_2385551_-\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	gnl\|CDD\|378065	pfam08843, AbiEii, Nucleotidyl transferase AbiEii toxin, Type IV TA system. This family was recently identified as belonging to the nucleotidyltransferase superfamily. AbiEii is the cognate toxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	9.75601e-08
NC_008639.1\|WP_011745866.1\|2375737_2376310_-\|hypothetical-protein	gnl\|CDD\|187735	cd09766, Csx15_I-U, CRISPR/Cas system-associated protein Csx15. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small protein loosely associated with CRISPR/Cas systems; some are fused to AAA ATPase domain, also known as TTE2665 family.	2.04612e-42

>NC_008639.1|WP_041467347.1|2390102_2390564_+|hypothetical-protein
MKIRVNSWTKLFLVQSSIQNPESKIQNLFTPLHPKARLDVGSAKRKQQTALISFRENSCQFVDKTLPLQSSIQNPKLKISSPLFIQKQGWIARWRNSKTALNPLRENPCQFVDKTLPLQSSIFNPKSRIQNSKSLHPSSSKSKAGWLDSEMAK
>NC_008639.1|WP_190271880.1|2389692_2389830_-|hypothetical-protein
MKIEEEEFCPRIDTNFHEEDLRLFCYFAISLSSYPAIQLSSLAFG
>NC_008639.1|WP_041467710.1|2389058_2389454_-|VOC-family-protein
MSVNAISTCITTEKVAESREFYVGHFNAEVTFDCGWYVNIRFAECSATLQFMAPREGQSPCNPAGLMYNISVPDVDEEYIRLTGEGLIPVMPLEDHPWGDRGFAVLDPNGVILYLFSERPASDEFKKYFLP
>NC_008639.1|WP_011745872.1|2386426_2388055_-|RelA/SpoT-domain-containing-protein
MKSKVSFEDACLHLKSIAGPTKMQLLALEDNCLNNNAVSKIYLTKYRIKKQESVYLKTKRKNKSLDEINDYGGLRLLCLFEDDIFDVHNDFVRMLHAKHYELKCCSAYNWNVKSIDKLRGEIDRYFDKNKYVFEKIKKTSGYKSVHYVVKQSGLDAEWIEVQLRTLVQDVWGELEHSISYKKGGIHPHIKKSFSLLSKELINIESLLSYLKEVNQKEIAGEEYYNKLVTPKYVFKYESQILPPCFEINVNLKVCYKQYWEIIESFETTSISHNWINQARAKLTEFNRNLTIDQLDENPELEYWIKMENAFLLFCDLKHEDSLKEYEKLLTKFGNRYCVHFRAGELYFILGHIEKALSSFDKAEDLIVVTEEIDHVNHYRIKTRLAYYYWSLGEEYIDISITEIKEAEEIFSKNKQLFDEAQYEQLVNNICWYKLEKYIIAVKKAESEETEENIRNADLAFEDVSSSYVVIDTLLKTNYISSHLLDTAAWYCYWVYKKTNDRAYLSKARDYALSINEKVKLTSYPFKSMKTHMNHIQAIMSAK
>NC_008639.1|WP_011745871.1|2384903_2385551_-|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein
MLPPSQLRLWPELDATPETFTLYGGTALALRFGHRVSVDFDFFSNKPFDPDELVDTLFYLKGAERLQVGPNTLTCRVDRGGPVLLSFFGGLGLGQVEAPDQAQGSTLFVASLLDIAGTKAAVVQKRAEVKDYLDMDALLQHGIDLPTVLAAGQVIYGCSFNPMITLKALSFFDDIPALPTDIRDRLCHAVDSVDPINLPVLKPYAERKIENGYNS
>NC_008639.1|WP_011745870.1|2384619_2384907_-|hypothetical-protein
MKTLPVTPEMLQVARRVVWFREPEDELADPVHFLAHVMTYGTVDDLQMLQGIAGKNEFSEVLENPPPGVFDARSWAYWNLKCGRQPAPPLPIRIL
>NC_008639.1|WP_011745869.1|2381638_2381923_-|CRISPR-associated-endonuclease-Cas2
MQFILVTYDIENDRRRTKIHKVLEGYGISVQYSVFECFLSDEDYAGLRIRLQKLMDPKHPLDSIRYYHLCRGCVEKVDVDGNRSFEIASPFIIT
>NC_008639.1|WP_011745868.1|2379402_2381598_-|CRISPR-associated-endonuclease-Cas1
MGWLYNQMAMPETIFQAWYKVASNDGRPGWDNTSIQDYSLRLEENLKSLSHALLTGTYRQSPLLKLVMLKPDGKERVLLIPGVIDRVAQTAASIVLSPIIEAELGNCTFAYRPGISREGAAREIDRLHREGYQWVLDADIRNFFDNVRHDLLFQRLVELVDDKEMISLLHRWLTAEIVDGLNPRTRNTMGLPQGCPISPALANLYLDRFDETMEQQGFKLVRFADDYLVLCKTRPKAEAALKLSESALAELKLELHSDKTRITTFAEGFKYLGYLFIRSLVIPTKMHPEEWYDKLGKFRLRKKSVHALPADPETMTGETSQFELETDQGEKIELSKEELLQTEFGKKLLESLDKKQLNVDEFLEKISRQDEERQKEKREALKKLYSPFLNTLYLQEQGSLMRKDGERFSIEKDGSVINEVIVRRIEQVVIFGNVALTTPVMQYCLQNEIPVTFLSQHGKYFGRLEATTADNAEMQRFHFLRSIDEPFALETARSIVAAKISNSKTMIRRRKTVVQDRDSTLQNKMAYNLDIMADLALKAEASTDIDALRGIEGKASALYFECYGMLFSKNLPFHTRSFLRVRRPPTDPVNSLLSFGYTMLHTNIFSMVQASGLNPYIGFLHAERKGNPALVNDLVEEFRTIVDSLVLYTLNRGLLQEKDFYYRKDEPGCFLSNDARKRFLNIFETRMWQESRDGCTGKTLNFRRHIEKQVRIMREVIAGTRTQYDPYKLPV
>NC_008639.1|WP_011745867.1|2376348_2377212_-|hypothetical-protein
MSTNPIQQKMRVQSLRRFAEGIVGRKNFGWWSLLYAALFFVVAGWFADGLAEFVDYVFSGQKRWILNYKLIVSAGLLFLFGWSIRNIAHDDHDEIAVNRDQPKPVRVLGLFLSNFLVRVDQTSHSGNSGDGFNKSALERAVSDSTFNRTMLLDTTWEMPFRAIEYHASSLERIELFTSSGGKCSSAESGLFIRLVAVLYPDVSVTEQIVDFEDLEVVFKAVEKLYADAEASGLKAQDVLVDITGGQKPNSIAAAIATLAVGRQFQYISTGDKVVRSYDVGYFQEDLS
>NC_008639.1|WP_011745866.1|2375737_2376310_-|hypothetical-protein
MNEFFTQNNLLVVFWYTAGIVSIIELLEYLVTRNIPWLLRLIRGLWRGVARRFRGDISQGARQLIINFSGHPVLPGQQQDIGQMMHWSSSEVINVSIGNVPEDHNFVPSIEKSVEKIPLSPEEWQSIPVVVIPSGYSQIWSVVMAELHGRLGYFPDVVRLRFSSSISNEKFEVAEIMNLREVRHNSRDKR
>NC_008639.1|WP_041467348.1|2392524_2392800_-|CRISPR-associated-endonuclease-Cas2
MFMLVSYDICDIKRLPRVAKLMEGYGVRVQYSVFECSLTQRQLMELQRRLKRLIKPEVDSVRFYPLCESCRDEIVILGQGTVSRDEPYYIA
>NC_008639.1|WP_011745875.1|2392803_2393847_-|CRISPR-associated-endonuclease-Cas1
MSEASLFLRTLYIQEQGSMLRVENGCFRVTCGHDDDVAELLEVQSIKVGQIVLFGACMITPAAIRHCLMNRIPVVLLSQHGEYFTRLESTDDVNIDLERLQFQRSAEESFPLECSRTIVRAKLHNSGVLLRRHAESSGSEALRHAATQLRQLEEHVDRADSIDAVRGYEGSGAATYFGVFEDFFDTGGFIFRERVKRPPTDPVNAMLSFGYSLLFNNIFSMARLHRLHPYVGFLHADKPAHPALVSDLIEEFRTLVDGLVIALINKRLISPEEFTVARHDDGKPKGCYLSDGARKTFLREFENLMHRTTTHPATGYEVTCRRCLDLQVGEFALYLKGEKPYTPYLRR
>NC_008639.1|WP_011745876.1|2393839_2394841_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MYTSLFPLRIARFRCTIEPLELVQLPDYKGSALRGGFGHAFRRATCLSRDRECESCMLKSACAYYTVFESRVSRQTADRLRIGADAPHPFLLEPPMTGQHCFEPGQKISYGLTLFGSAIEKLPFFIYAFMILGENLGLGKGRGRFRLLAVEDEGGRNLYHDGHLSGGFVILSARDILESTSTDDRPLALRFETPLRMKTAWQRKEQELLTGIGHEDDFRLLLKSLYHRAFVLTQLYGDLPEPASYNSRNLPLVNGDVHLGSAETRWLDWTRYSQRHQQHMQLGGILGSVTFTGKTGQYLPLFRLGEYLHIGKGTTFGLGKYRMVEPVPEQTGE
>NC_008639.1|WP_041467349.1|2395244_2395529_-|hypothetical-protein
MPTNYTNLHEKRIGSWFSLASPIKTTAGFSIKRRMGMKMGSFAHELREFARKGIKALLLFRHLAIQLSSLAFGLKRGGGDFEFWIMNCGLKIED
>NC_008639.1|WP_011745877.1|2396579_2396849_-|hypothetical-protein
MRSCRDDAETLILLDEVVIVEKRLDIVEAQNRRKAEPWVGVVAGSNIVEHAEGREDVLRQIEDRIRRRQNLKKLEEYFKQRRIQRDGVG
>NC_008639.1|WP_011745878.1|2396879_2397422_-|hypothetical-protein
MRHFQAFVRASAITVVCVALFFNNALAIDAVPWLKLSEEARFAFVIGFNAGVSHGAVSAGAEAQRIYVPSTGFDQSQSFEEMVNSPEAKRNWENSVRIQKVAMKESGLRHGVSSVVDQMDFLYKDPATKVIGWSWMIGIAQDRLDGKDVSGSINSMIKADKFWDTVLRSNEPVFNFKKSK
>NC_008639.1|WP_150081108.1|2398448_2399168_-|hypothetical-protein
MRPSEYFRQTGTRPTAAARRKEPMPEPEPSFIDAETAGRSLTAYEQNNFALWLVRVFGEETAFQLVDAYHVGTSKHWPGACIFWQQDVTGKLRGGKIMLYNKETGRRVTEPFPHVQWVHKVLKIQPYHLRQCLFGEHLLVADRERAVGIVESEKTTVVAAGFMPEMLWLATAGKNNLKAERLDVLGGRNVTLFPDLGAFEKWEEIARGMPGVKVSDILERRASEADRAGGLDLADYLLR
>NC_008639.1|WP_011745880.1|2399323_2401234_-|hypothetical-protein
MTSIIDEIRAEVLKPAEKFSSGGVFEQTDVHYVHHVHQSETDEQELERCVTVVEDVVRRGKDEPGLYGSDAFRAAWTHICKSSDEQRFRLRVKIKENKPIGVPLGEIDRVGSGGEGGEDRSAADELVSLAVGAGELFFDETTRDGFVTVGSDTMRVRSVAFLDWLSYRHYRESGGSSASDSALKQACGTLSGLCQHEGKPERVFLRAGRNSETGAYYLHGIGKNGQSAEVTATGWRLLEVAPVKFWRSGSAVPFPEPIAGGDIGKLWDLVNIPEADRVLVLAWILEAWRPDTPFPALELCGVQGSAKSSTQKRLRMLVDASSAPLRAAPKTVEDAFVSAGNNWVVSLDNVSHLSAGLQDAFCIMATDGAYAGRTLFTNADETVITIKRPVVLSGINNPVTAQDLISRTVHIELPVIEGRRRLESELDAAFNEAWPEIFGGLLDLFVKTLRMLPETVLPVDALRMADFNHLGEAMARAMGYKPGAFTSLYRGNYRESVQRAMESSPVAVAVAQMAEDSPLQEVFDGTYKELLEKLVTHKTDNEGWPKSEKGLANALKRQMPALQEIGVVLIPETGPKQSKKGRRIVIRKGEHGEHSEHGNVQKAPEEKKYPIGCGSDGSDGSNDPCEPTGTSDDMPF
>NC_008639.1|WP_011745881.1|2401230_2401506_-|hypothetical-protein
MTRKSKSLTGREVRLKKEIDADGRDQREQPQDNQPVDNFKAFDLETYERNVRRACIDAYVLLKDFPSSLRFSYFVGSDGKLLVRGERGGAK
>NC_008639.1|WP_190271881.1|2401509_2401656_-|hypothetical-protein
MTITKSTVFKWSMLGKIPCQKAPNGRLLFPVDKVQQWIESGNVEQGEG

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Crispr_ID: NC_008639_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008639_7

2512615-2512860

Orphan

Consensus_repeat	Method
ACCNGANGGCAGACCGGA	CRT

5 spacers

The CRISPR arrays of NC_008639_7

>merge|NC_008639|7|2512615-2512860|CRT
ACCTGATTTCAGACCGGATGGCAGGCCTGACGGCAGACCCGATGGCAGACCGGACGGCAGGCCTGATTTCAGACCGGATGGCAGGCCTGACGGCAGGCCTGACGGCAGACCGGACGGCAGACCGGACGGCAGACCGGACGGCAGACCGGACGGCAGACCGGATTTCAGACCGGATGGCAGGCCTGACGGCAGGCCTGACGGCAGACCGGACGGCAGACCGAACGGCAGACCGAACGGCAGACCTGA

>NC_008639|7|6|2512615-2512860|CRT
ACCTGATTTCAGACCGGA	TGGCAGGCCTGACGGCAG
ACCCGATGGCAGACCGGA	CGGCAGGCCTGATTTCAGACCGGATGGCAGGCCTGACGGCAGGCCTGACGGCAG
ACCGGACGGCAGACCGGA	CGGCAGACCGGACGGCAG
ACCGGACGGCAGACCGGA	TTTCAGACCGGATGGCAGGCCTGACGGCAG
GCCTGACGGCAGACCGGA	CGGCAGACCGAACGGCAG
ACCGAACGGCAGACCTGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008639.1\|WP_190271942.1\|2520705_2520870_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745965.1\|2503546_2504389_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NC_008639.1\|WP_011745969.1\|2506761_2508024_+\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NC_008639.1\|WP_011745973.1\|2510835_2512110_+\|Ni/Fe-hydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|225798
NC_008639.1\|WP_150081230.1\|2516567_2516816_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|182103
NC_008639.1\|WP_011745983.1\|2521323_2521638_+\|BrnA-antitoxin-family-protein	unknown	unknown	gnl\|CDD\|372110
NC_008639.1\|WP_150081139.1\|2513932_2514691_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224401
NC_008639.1\|WP_011745972.1\|2510081_2510846_+\|NADH-ubiquinone-oxidoreductase	unknown	unknown	gnl\|CDD\|224852
NC_008639.1\|WP_081428238.1\|2513409_2513730_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275085
NC_008639.1\|WP_011745978.1\|2516917_2517139_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|274230
NC_008639.1\|WP_011745971.1\|2509246_2510071_+\|FAD/NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|99817
NC_008639.1\|WP_011745974.1\|2512177_2512357_+\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745980.1\|2518883_2520080_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226984
NC_008639.1\|WP_011745977.1\|2514774_2516346_-\|IS21-family-transposase	unknown	unknown	gnl\|CDD\|226950
NC_008639.1\|WP_011745981.1\|2520073_2520679_+\|DUF4276-family-protein	unknown	unknown	gnl\|CDD\|379470
NC_008639.1\|WP_011745967.1\|2504875_2505682_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|349968
NC_008639.1\|WP_150081110.1\|2504425_2504767_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745968.1\|2505678_2506536_-\|hypothetical-protein	unknown	unknown	unknown
NC_008639.1\|WP_011745970.1\|2508113_2509193_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|131956
NC_008639.1\|WP_011745979.1\|2517135_2517531_+\|type-II-toxin-antitoxin-system-death-on-curing-family-toxin	unknown	unknown	gnl\|CDD\|226180

Protein	Function_ID	Function_description	E-value
NC_008639.1\|WP_011745965.1\|2503546_2504389_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	1.50054e-10
NC_008639.1\|WP_011745980.1\|2518883_2520080_+\|AAA-family-ATPase	gnl\|CDD\|226984	COG4637, COG4637, Predicted ATPase [General function prediction only].	6.81412e-46
NC_008639.1\|WP_011745973.1\|2510835_2512110_+\|Ni/Fe-hydrogenase-subunit-alpha	gnl\|CDD\|225798	COG3259, FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion].	2.68659e-101
NC_008639.1\|WP_150081230.1\|2516567_2516816_-\|TolC-family-protein	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	3.72157e-18
NC_008639.1\|WP_011745983.1\|2521323_2521638_+\|BrnA-antitoxin-family-protein	gnl\|CDD\|372110	pfam12441, CopG_antitoxin, CopG antitoxin of type II toxin-antitoxin system. CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.	4.71563e-37
NC_008639.1\|WP_150081139.1\|2513932_2514691_-\|ATP-binding-protein	gnl\|CDD\|224401	COG1484, DnaC, DNA replication protein [DNA replication, recombination, and repair].	8.8338e-44
NC_008639.1\|WP_011745972.1\|2510081_2510846_+\|NADH-ubiquinone-oxidoreductase	gnl\|CDD\|224852	COG1941, FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit [Energy production and conversion].	1.74711e-41
NC_008639.1\|WP_081428238.1\|2513409_2513730_-\|hypothetical-protein	gnl\|CDD\|275085	TIGR04258, hypothetical_protein, four helix bundle suffix domain. This domain occurs as a suffix domain to some members of the much broader protein family TIGR02436, a few of whose other members are encoded within intervening sequences of bacterial 23S ribosomal RNA. Some proteins with this domain, in turn, are followed by a predicted DNA topoisomerase type C4 zinc finger.	8.16334e-17
NC_008639.1\|WP_011745978.1\|2516917_2517139_+\|transcriptional-regulator	gnl\|CDD\|274230	TIGR02609, hypothetical_protein_XAC1195, putative addiction module antidote. Members of this protein family are putative addiction module antidote proteins that appear recurringly in two-gene operons with members of the Doc (death-on-curing) family TIGR01550. Members of this family contain a SpoVT/AbrB-like domain (pfam04014). Note that the gene pairs with a member of this family tend to be found on bacterial chromosomes, not on plasmids. [Mobile and extrachromosomal element functions, Other].	5.41472e-14
NC_008639.1\|WP_011745971.1\|2509246_2510071_+\|FAD/NAD(P)-binding-protein	gnl\|CDD\|99817	cd06221, sulfite_reductase_like, Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is linked to ferredoxin and reduces NH2OH and SeO3 at a lesser rate than it's normal substate SO3(2-). Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to orotate coupled with the reduction of NAD+.	8.10969e-124
NC_008639.1\|WP_011745977.1\|2514774_2516346_-\|IS21-family-transposase	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.38986e-24
NC_008639.1\|WP_011745981.1\|2520073_2520679_+\|DUF4276-family-protein	gnl\|CDD\|379470	pfam14103, DUF4276, Domain of unknown function (DUF4276). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 224 amino acids in length. There is a single completely conserved residue E that may be functionally important.	1.80779e-12
NC_008639.1\|WP_011745967.1\|2504875_2505682_-\|RNA-methyltransferase	gnl\|CDD\|349968	cd18095, SpoU-like_rRNA-MTase, SAM-dependent rRNA methylase related to SpoU-TrmH. RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	1.00695e-57
NC_008639.1\|WP_011745969.1\|2506761_2508024_+\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	3.71742e-106
NC_008639.1\|WP_011745970.1\|2508113_2509193_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|131956	TIGR02910, anaerobic_sulfite_reductase_subunit_A, sulfite reductase, subunit A. Members of this protein family include the A subunit, one of three subunits, of the anaerobic sulfite reductase of Salmonella, and close homologs from various Clostridum species, where the three-gene neighborhood is preserved. Two such gene clusters are found in Clostridium perfringens, but it may be that these sets of genes correspond to the distinct assimilatory and dissimilatory forms as seen in Clostridium pasteurianum. Note that any one of these enzymes may have secondary substates such as NH2OH, SeO3(2-), and SO3(2-). Heterologous expression of the anaerobic sulfite reductase of Salmonella confers on Escherichia coli the ability to produce hydrogen sulfide gas from sulfite. [Central intermediary metabolism, Sulfur metabolism].	1.51943e-40
NC_008639.1\|WP_011745979.1\|2517135_2517531_+\|type-II-toxin-antitoxin-system-death-on-curing-family-toxin	gnl\|CDD\|226180	COG3654, Doc, Prophage maintenance system killer protein [General function prediction only].	4.62519e-39

>NC_008639.1|WP_011745974.1|2512177_2512357_+|hypothetical-protein
MKKSLVLAAAGIAGVLLCTPKSNAQADLNLHLNIGGSPAVVVDRSPDFIYLDDYGLAVS
>NC_008639.1|WP_011745973.1|2510835_2512110_+|Ni/Fe-hydrogenase-subunit-alpha
MKLDCSIDIRHLTRVEGHGNILIRVEKGQLVEARWDVVETPRFFEVMLKGMSAERVPFLTSRICGICSISHALASIRALERAMQVTPPPTAEAVRLLAMHGETLQSHALHLFFLAAPDFAGTPSVLPLMESNPELVKAGLAIKELGNEISTVTAGRCTHPVSLVAGGISKAPDSNNLQRLLGMISERKAALVLACDFFASLDIPRFERETEFISLYNGATYPFIGGDLCSTDGVREEENNYLRMTNEYLAEPSTSKFTRCSRESSAAGALARFNNNSEFLHPEAKKAAERLGLRPISHNPFMCNIAQLVECVHILYDAETLIRKLLDMDLLEIRSVVKPKAGSATGAVEAPRGILYHHMETDEEGRIVKANCIIPTTQNNANIHHDLGALARQALEEGKNDQEIEKLATMLVRSYDPCISCSVH
>NC_008639.1|WP_011745972.1|2510081_2510846_+|NADH-ubiquinone-oxidoreductase
MNQQGMHFEKLKFASFEFTCCEGCQLQLANHESSLAAFFDLLDVRAFREISSEKHDDYDIAFVEGSISRNDEIERLLTIRRQAKTLVAFGTCACFGGVNSLKNRFPIEECIAEVYDSQPIESLPVRKISDFVKVDLSIPGCPVAKEEVERIVVCLVTSSLVTLPKYPVCVECKEQLNTCLFDLGDICLGPITRAGCNAVCTSGKTPCLGCRGPAEDINFPAFMELVKKRGLNRGDLQEKLGFYNAFEAYRNDET
>NC_008639.1|WP_011745971.1|2509246_2510071_+|FAD/NAD(P)-binding-protein
MKTDMGYKCRITNVVSLTEQEKLFQLHIVDPQERRIFRFKPGQFIMLELPGYGDVPISISSSYSNHEFIELCIRKAGHVTSALFRTEPGMHVAIRGPFGSSFPMDEIAGHHVLLVAGGLGIAPLRAPLFWINEHRDRFRDVHLLYGAREPSQLLFSYQFDEWNTISHVRLHTIVEHSDETWKGRTGMITELFRDIEIDTKNTYAIVCGPPIMFKFVCSYLDRLGIPMNRMFVSLERRMHCGMGKCCRCMVGSTFTCIDGPVFDYWSVMNLKEAI
>NC_008639.1|WP_011745970.1|2508113_2509193_+|4Fe-4S-dicluster-domain-containing-protein
MIYKVISKAEFIRFIDALVQNNSSFGPRQVDTDSRGNPLYQFKPVTSADEIAFDYTITTSSAKHFFLPFSEELSRFSFNKTDWEQHITYESDPVVLIGLRPCDISALNILDDVLLKGHYPSPYYLAKRKNTFVIGMDHLPLPDCFCKSLAHHTVSTGFNLFCSDIGEKYYLSINSSKAFTYLQEFQTDDPSYEDNCLLTERRNLISNSFKTEIDVTSLPSILDIEFDSAVWEKWGAKCLNCGTCAMVCPTCYCYSLIERFDTDLKGASRNRKLYSCNLIDFAVVAGGHNFRPKNGDRLKYRYYHQHRGFAENGNQQICVGCNRCGRACLAGINPKDVINELRMEKESCMICASQSPGKT
>NC_008639.1|WP_011745969.1|2506761_2508024_+|U32-family-peptidase
MNLSESVTSEKKIELIAPAGDWTSLRTALQAGADAVYFGAEGYNMRAGSNNFTPADFPAIMTLCSEFNAKAYLALNTIVYDGELKKMVQTVSAAKTTGFDAVICSDMAVVDACRKAAMPFHMSTQASISNYSAVKFYADLGAKMIVLARELTIDQVRHITSKLKADRLDVQIECFVHGAMCVAVSGRCFMSQELFGRSANRGQCVQPCRRQYIITDPEENQELELGTDYVMSPKDMCAVEFLDVLMDAGISAFKIEGRSRSPEYVHTATTAYRRAIDFCTSHRNSPEFRTEYNSLSKQLKEELARVYNRGFSEGFYFGKPFDAWTREYGSMASEKKIYIGEVKKYYPKAEVAEILIFARGLKQGDKLSVLGPKTGVTTLFAESFYTNDLPAKTAVRGDSVTIKCAKVRKNDKVYVLEKRS
>NC_008639.1|WP_011745968.1|2505678_2506536_-|hypothetical-protein
MGIFFVQLGERYNRNGMNERVMVKMFLSLSTLLFIAELVVGLFYQADLRLMVLFFMLAVSLAGILVSLKMLLGEKQEVESVSMRRRRALDDEVMKDVLDGYEVDEEFLGNVSRKGKKRGGSGAVREQNISAGASGAKDESSLEDAIRSHAVMFGGLEKLLDALTEVDELSFGKMMEKAGIQGVARGEVIVQIQTMVDLEQRSCGELLKRTEDSLSEGLSLDKESFDEYIRRCMTTSESESAPVSTTFSLDLDMAAMSKQDGTPPKDFSHAPEAVFSKLKKPGKEV
>NC_008639.1|WP_011745967.1|2504875_2505682_-|RNA-methyltransferase
MTSSDLNPLSKVKLRRFVKLQEKKYRDQDGLFLAEGLRTVRELCQNIPDESMLLALLLREGEIGLGGFPEIPEDKLYVMNSEQCSLLSSTAAPQGVIGVFRQQQVSRYPCGFKDEKKGRSLLIALDEVQDPGNVGTILRTAAWFGADALICSTGTADRYNAKVVRSSAGSLYALPHYTVERLDLALEELAASGYAIICSSLDGEDFRSFVSWPQKQVLVIGNEANGVSRVVQNLAERLVRIPHGGGKSRVESLNASVSAAILMERLVL
>NC_008639.1|WP_150081110.1|2504425_2504767_-|hypothetical-protein
MKNMLCFRLLLCGALSFPLVSCVTAYPYRTGSHYVWIPAHRTPQGVYVRRHRQYIGPPPRYGSVWVPGYYGHGGVWTDGGWRDNNRKESDRKKYDRRDSDRRDYDRKDSGRRN
>NC_008639.1|WP_011745965.1|2503546_2504389_+|universal-stress-protein
MSSNSFLIRTIAVAIDCSPHSLASLNTAAELAGFLHANLTGIFVEDINLLRLADIPLSREIDFFSEKTENIEITGLEQLLQIQEQQAETSLQKAAGKFMVKHTFRVCRGKVPEEVVIASLEADLLVLGRRGKSPTCRKGLGSTAQNALKQRKKTVLFMRSGFSVQEESALVLYDGSAASETALDAAMNVIRPGNTLQILMLPFEKNERDMETGLSERFASDMPKIEYHAIPPVTDGKALARYIRMADSGLLFLSDRMNLPSETVHSLVNKIDYPVMVVRG
>NC_008639.1|WP_081428238.1|2513409_2513730_-|hypothetical-protein
MQPKTLHEVQAWVAEERRVATEAQGLSRTHTDRQDAGRSSVPVRECQDSSILSSACLAANGALSLLNLACYLLDRQVAKLAAGFENEGGFTERLYRVRTARRNQQR
>NC_008639.1|WP_150081139.1|2513932_2514691_-|ATP-binding-protein
MLEEARKSEPSYSDFALTLLESELSCRRKAHLERRRKIANLPLLHDLDHYDSGVQNGISQVQLQQLRQLLWLDQNFNLILIGPSGTGKSYLAGGLCHEALKLGYHALFRTMDDLIQTIRFKEITAAAAREYKRLLSAHLLVIDDIMMFPLEKSVAVGLFQLVNQLHEQTSFIITTNKSPKEWAEMLGDEVLATALLDRLLYKCEVIKLTGKSYRLEHRTTIFEQQQSPEGGGNRRKKQLPLQKGVGNHCKMT
>NC_008639.1|WP_011745977.1|2514774_2516346_-|IS21-family-transposase
MRTQLKKLTMYNKVKEFAREGLSIRQISRKTGMDRVTVRKFLRMTDEEFSAFLALQKRRLRKLQPYEQFVKDRVTDYPDCSATQVEDWLKEHHPVFPEVTTRTIYSFVQWIRKAYDLPKPKGTPRAYHPVEQLPYGEQAQVDFGEYWMASADACKVKVHFMIMLLSRSRRKFVSFSQQPITTRFVFEAHEQAFSFFEGIPHTLVYDQDSTIVTDENRGAILYTEAFRKYLLHRSLKIHLCRKSDPESKGKIEAGVKYVKYNFLPGRRFVNLEVLNQEALLWLERTANAKEHATTRLIPDAEWQVEKQHLRPFEPLPYPISGTVGKEYHVRKDNTISYRGNFYSLPVGTYAGPGTLVVLEVRQNTLCLYAQEGRLLANHPIESGKGTVVINNNHRRDTSSKLRELQDSLMLLFTNQEHAERFLESIHNRYPRYSRDQFLHVRNAISGCQQKLIDDALAHCVDHHLFSSGEFHDILHHYRKQEEKQSHQAVFNTFRPKTLRSDMDRMLSFVPDSSGITTYENIFS
>NC_008639.1|WP_150081230.1|2516567_2516816_-|TolC-family-protein
MERPFLRRTCCQPANANIGAAQASFFPSIGLTGSASTSLSDLFVTGSSGVWSFAPQGTFRIFQGGRLRSNLKMAESSTAILP
>NC_008639.1|WP_011745978.1|2516917_2517139_+|transcriptional-regulator
MRATVTKIGNSTGVILPKAATDRLKVKQGDIVFLTETPTGYTVTPYDPEFAKQMEAARCGMKEYRNALHELAK
>NC_008639.1|WP_011745979.1|2517135_2517531_+|type-II-toxin-antitoxin-system-death-on-curing-family-toxin
MSWHWLLDEVVIAIHDEQIAVHGGSLGIRDSGLLYSALARPKHKANYGDPSVFDLAAAYAYGIIRNHPFVDGNKRTGFLVAYVFLHINGWELRSIEVEAVNAVLDLAAGEMDEPFFSEWLKNKSVIRTARK
>NC_008639.1|WP_011745980.1|2518883_2520080_+|AAA-family-ATPase
MIQSIRLDNLLSFASGSPALELKNLNVLIGTNGSGKSNLIEALALVRTAPRTSSNDDFQRTISRGGTISEWIWKGDANRPATIELVLDNPYATQSNHKQPLRHSFTFKGEQQRVIFVDERIENKAPYPDQPFNQYFYYRCYKGNPLINSAIGGERKLGRDSVSSELSILAQRRDPEQYPEITWLADQYEQFSFYREWTFGRNTVFRNPQRGDLRNDRLEEDFSNLGLFLNRLKTHKPKAKSEILNGLKELYNGVDDFNVNIEGGTVQLFFTEGEFAIPATRLSDGTLRYLCLLALLCDPDPPKLLCIEEPELGLHPDILPKLADLLIEASQRTQIIVTTHSDILVDAMTETPESVVVCEKQDGKTNMTRLDKNALAVWLDHYRLGQLWTRGEIGGTRW
>NC_008639.1|WP_011745981.1|2520073_2520679_+|DUF4276-family-protein
MVKAIIYLEGGGESKELHTRCREGFHKLLEKNGFKGKMPRLVASGSRFSAFSDFKAAHQSKMHTFVALWIDSEDPVADIEKTWAHLEKRDGWEQPDNSCNEQVLLMTTCMETLIATDREALKTCCSCKDKLHESALPPLHNMESRSRKEIFDTLKRATRDCQALYEKGEKSFELLGMLNTEILRQHLPSVARSWRILDKKL
>NC_008639.1|WP_190271942.1|2520705_2520870_-|hypothetical-protein
MVRGIEQGNFVLDDSDRVEFLHEKVRCDWVDRDNVLRFFGSREGAAREAFSGVS
>NC_008639.1|WP_011745983.1|2521323_2521638_+|BrnA-antitoxin-family-protein
MKKQKKTVPEFRSEQDEREFWATHDSSEYIDWEKAGTAIFPDLKPTMKTISLRLPEQMLNRIKVLANERDVPYQSLLKMFLKERIDREYEPKRNKPRSSRKANA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_008639_6	6.14\|2391708\|44\|NC_008639\|CRISPRCasFinder,CRT,PILER-CR	2391708-2391751	44	NC_008639.1	2302634-2302677	0	1.0

1. spacer 6.14|2391708|44|NC_008639|CRISPRCasFinder,CRT,PILER-CR matches to position: 2302634-2302677, mismatch: 0, identity: 1.0

ccgttatgtgctatggcaaggctgccggaacgataggttaaaga	CRISPR spacer
ccgttatgtgctatggcaaggctgccggaacgataggttaaaga	Protospacer
********************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_008639_3	3.3\|1625525\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625525-1625558	34	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	462827-462860	7	0.794
NC_008639_3	3.24\|1626923\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1626923-1626956	34	KU878088	Bacillus phage AR9, complete genome	153341-153374	7	0.794
NC_008639_7	7.4\|2512777\|30\|NC_008639\|CRT	2512777-2512806	30	NZ_CP019037	Massilia putida strain 6NM-7 plasmid unnamed2, complete sequence	443932-443961	7	0.767
NC_008639_7	7.4\|2512777\|30\|NC_008639\|CRT	2512777-2512806	30	NC_019789	Deinococcus peraridilitoris DSM 19664 plasmid pDEIPE01, complete sequence	6880-6909	7	0.767
NC_008639_3	3.49\|1628582\|33\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1628582-1628614	33	AP013368	Uncultured Mediterranean phage uvMED DNA, complete genome, group G11, isolate: uvMED-CGR-U-MedDCM-OCT-S25-C42	19319-19351	8	0.758
NC_008639_4	4.18\|2378016\|32\|NC_008639\|PILER-CR	2378016-2378047	32	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	805991-806022	8	0.75
NC_008639_7	7.4\|2512777\|30\|NC_008639\|CRT	2512777-2512806	30	MK388859	Klebsiella phage ST405-OXA48phi1.1, complete genome	19080-19109	8	0.733
NC_008639_3	3.3\|1625525\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625525-1625558	34	AP014684	Pseudomonas phage PS-1 DNA, complete sequence	20476-20509	9	0.735
NC_008639_3	3.3\|1625525\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625525-1625558	34	NC_047955	Pseudomonas phage Nerthus, complete genome	25303-25336	9	0.735
NC_008639_3	3.30\|1627325\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1627325-1627358	34	MT460514	Vibrio phage AG74, complete genome	20713-20746	9	0.735
NC_008639_3	3.30\|1627325\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1627325-1627358	34	MK796244	Vibrio phage Achelous, complete genome	20519-20552	9	0.735
NC_008639_3	3.30\|1627325\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1627325-1627358	34	MN966731	Vibrio phage Chazly21, complete genome	21195-21228	9	0.735
NC_008639_3	3.30\|1627325\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1627325-1627358	34	MK907780	Vibrio phage Pontus, complete genome	22149-22182	9	0.735
NC_008639_3	3.30\|1627325\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1627325-1627358	34	MK895508	Vibrio phage Brizo, complete genome	17172-17205	9	0.735
NC_008639_3	3.82\|1630785\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1630785-1630818	34	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	227229-227262	9	0.735
NC_008639_3	3.111\|1632713\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1632713-1632746	34	NZ_CP049243	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed2, complete sequence	91642-91675	9	0.735
NC_008639_2	2.7\|1622518\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1622518-1622551	34	MH616983	Microviridae sp. isolate ctje725, complete genome	3122-3155	10	0.706
NC_008639_3	3.3\|1625525\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625525-1625558	34	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	527087-527120	10	0.706
NC_008639_3	3.3\|1625525\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625525-1625558	34	MT152150	Pseudomonas phage 8P, complete genome	31080-31113	10	0.706
NC_008639_3	3.3\|1625525\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625525-1625558	34	JF974309	Rhodobacter phage RcNL1, * SEQUENCING IN PROGRESS *, 5 unordered pieces	36892-36925	10	0.706
NC_008639_3	3.3\|1625525\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625525-1625558	34	NZ_CP013454	Burkholderia vietnamiensis strain MSMB608WGS plasmid pMSMB608, complete sequence	114882-114915	10	0.706
NC_008639_3	3.3\|1625525\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625525-1625558	34	NC_016165	Rhodobacter phage RcapMu, complete genome	32466-32499	10	0.706
NC_008639_3	3.4\|1625591\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625591-1625624	34	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	1705706-1705739	10	0.706
NC_008639_3	3.4\|1625591\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625591-1625624	34	NZ_CP015881	Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence	511725-511758	10	0.706
NC_008639_3	3.40\|1627985\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1627985-1628018	34	NZ_CP044049	Klebsiella variicola strain FDAARGOS_627 plasmid unnamed1, complete sequence	165041-165074	10	0.706
NC_008639_3	3.76\|1630383\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1630383-1630416	34	NC_011961	Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence	42351-42384	10	0.706
NC_008639_3	3.95\|1631652\|33\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1631652-1631684	33	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	232047-232079	10	0.697
NC_008639_3	3.95\|1631652\|33\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1631652-1631684	33	NZ_CP054618	Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence	160372-160404	10	0.697
NC_008639_3	3.112\|1632779\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1632779-1632812	34	NZ_CP028969	Aminobacter sp. MSH1 plasmid pUSP1, complete sequence	245605-245638	10	0.706
NC_008639_3	3.112\|1632779\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1632779-1632812	34	NZ_CP026266	Aminobacter sp. MSH1 plasmid pAM01, complete sequence	242882-242915	10	0.706
NC_008639_3	3.4\|1625591\|34\|NC_008639\|PILER-CR,CRISPRCasFinder,CRT	1625591-1625624	34	NZ_CP019603	Croceicoccus marinus strain E4A9 plasmid pCME4A9I, complete sequence	585022-585055	11	0.676
NC_008639_3	3.70\|1629984\|35\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1629984-1630018	35	NC_012521	Rhodococcus opacus B4 plasmid pROB02, complete sequence	56212-56246	11	0.686
NC_008639_3	3.78\|1630516\|36\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1630516-1630551	36	NZ_CP017077	Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence	333274-333309	11	0.694
NC_008639_3	3.82\|1630785\|34\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1630785-1630818	34	KY653116	Staphylococcus phage IME1318_01, complete genome	31716-31749	11	0.676
NC_008639_3	3.94\|1631585\|35\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1631585-1631619	35	NZ_CP007794	Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence	1145312-1145346	11	0.686
NC_008639_3	3.94\|1631585\|35\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1631585-1631619	35	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	1522660-1522694	11	0.686
NC_008639_3	3.94\|1631585\|35\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1631585-1631619	35	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	1811090-1811124	11	0.686
NC_008639_3	3.70\|1629984\|35\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1629984-1630018	35	NZ_CP046574	Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence	81413-81447	12	0.657
NC_008639_3	3.70\|1629984\|35\|NC_008639\|CRT,PILER-CR,CRISPRCasFinder	1629984-1630018	35	NC_008271	Rhodococcus jostii RHA1 plasmid pRHL3, complete sequence	262379-262413	12	0.657

1. spacer 3.3|1625525|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.794

--aaggccaaatcgaccacatcgacggcgacggtct	CRISPR spacer
tcgagatcaa--cgacgacatctacggcgacggtct	Protospacer
  .**..***  **** ***** *************

2. spacer 3.24|1626923|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to KU878088 (Bacillus phage AR9, complete genome) position: , mismatch: 7, identity: 0.794

aaatcaagatagagtattatgagtacctttacgc	CRISPR spacer
cattagagatagagtattatgaagacctttaccc	Protospacer
 * * .****************. ******** *

3. spacer 7.4|2512777|30|NC_008639|CRT matches to NZ_CP019037 (Massilia putida strain 6NM-7 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

tttcagaccggatggcaggcctgacggcag	CRISPR spacer
tggtcgaccggatggcgggcatgacggcaa	Protospacer
*  . ***********.*** ********.

4. spacer 7.4|2512777|30|NC_008639|CRT matches to NC_019789 (Deinococcus peraridilitoris DSM 19664 plasmid pDEIPE01, complete sequence) position: , mismatch: 7, identity: 0.767

tttcagaccggatggcaggcctgacggcag	CRISPR spacer
cgtcggtacggatggcagggctgacggcaa	Protospacer
. **.*  *********** *********.

5. spacer 3.49|1628582|33|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to AP013368 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G11, isolate: uvMED-CGR-U-MedDCM-OCT-S25-C42) position: , mismatch: 8, identity: 0.758

ttaattagtggatgagacaatgacaacaaaaca	CRISPR spacer
ttgttgggtggatgagacaattaaaacaaaaac	Protospacer
**. * .************** * *******

6. spacer 4.18|2378016|32|NC_008639|PILER-CR matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 8, identity: 0.75

-tatcaagttttcgtaaacggtatgatggagct	CRISPR spacer
atagc-agttttcggatacggtatgatgggtaa	Protospacer
 ** * ******** * ************.

7. spacer 7.4|2512777|30|NC_008639|CRT matches to MK388859 (Klebsiella phage ST405-OXA48phi1.1, complete genome) position: , mismatch: 8, identity: 0.733

tttcagaccggatggcaggcctgacggcag	CRISPR spacer
gactgcacgggatggcaggcctgacggcgg	Protospacer
  ... ** *******************.*

8. spacer 3.3|1625525|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to AP014684 (Pseudomonas phage PS-1 DNA, complete sequence) position: , mismatch: 9, identity: 0.735

aaggccaaatcgaccacatcgacggcgacggtct	CRISPR spacer
agaaccagatcgaccacatcgatggcgaccgctc	Protospacer
*...***.**************.****** *...

9. spacer 3.3|1625525|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to NC_047955 (Pseudomonas phage Nerthus, complete genome) position: , mismatch: 9, identity: 0.735

---aaggccaaatcgaccacatcgacggcgacggtct	CRISPR spacer
acaagaaccg---cgaccacatcgacatcgacggtct	Protospacer
   *...**.   *************. *********

10. spacer 3.30|1627325|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to MT460514 (Vibrio phage AG74, complete genome) position: , mismatch: 9, identity: 0.735

cattatcgtaatccattgttgacagcaaagtgtt	CRISPR spacer
tgtgtgcgttatccattgttgacagcatagtgaa	Protospacer
..*   *** ***************** ****

11. spacer 3.30|1627325|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to MK796244 (Vibrio phage Achelous, complete genome) position: , mismatch: 9, identity: 0.735

cattatcgtaatccattgttgacagcaaagtgtt	CRISPR spacer
tgtgtgcgttatccattgttgacagcatagtgaa	Protospacer
..*   *** ***************** ****

12. spacer 3.30|1627325|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to MN966731 (Vibrio phage Chazly21, complete genome) position: , mismatch: 9, identity: 0.735

cattatcgtaatccattgttgacagcaaagtgtt	CRISPR spacer
tgtgtgcgttatccattgttgacagcatagtgaa	Protospacer
..*   *** ***************** ****

13. spacer 3.30|1627325|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to MK907780 (Vibrio phage Pontus, complete genome) position: , mismatch: 9, identity: 0.735

cattatcgtaatccattgttgacagcaaagtgtt	CRISPR spacer
tgtgtgcgttatccattgttgacagcatagtgaa	Protospacer
..*   *** ***************** ****

14. spacer 3.30|1627325|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to MK895508 (Vibrio phage Brizo, complete genome) position: , mismatch: 9, identity: 0.735

cattatcgtaatccattgttgacagcaaagtgtt	CRISPR spacer
tgtgtgcgttatccattgttgacagcatagtgaa	Protospacer
..*   *** ***************** ****

15. spacer 3.82|1630785|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 9, identity: 0.735

ggaggacatc------ttcatcaattcttcatctgtgatt	CRISPR spacer
------caccacttctttcatcaattcttcaacggtgatt	Protospacer
      **.*      *************** * ******

16. spacer 3.111|1632713|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP049243 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

------cgtttctcgatcaagtgatcggcgatatacggca	CRISPR spacer
accaggcgt------atcaagtgctcggcgatatactgcg	Protospacer
      ***      ******** ************ **.

17. spacer 2.7|1622518|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to MH616983 (Microviridae sp. isolate ctje725, complete genome) position: , mismatch: 10, identity: 0.706

ctagatgtgttgtgtttgttgattgccagacaga	CRISPR spacer
cgagatgtgttgtgattgctgattgcaatcgttg	Protospacer
* ************ ***.******* *     .

18. spacer 3.3|1625525|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 10, identity: 0.706

aaggccaaatcgaccacatcgacggcgacggtct	CRISPR spacer
tccgcggcgtcggcgacatcgacggcgacggtca	Protospacer
   ** . .***.* ******************

19. spacer 3.3|1625525|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to MT152150 (Pseudomonas phage 8P, complete genome) position: , mismatch: 10, identity: 0.706

aaggccaaatcgaccacatcgacggcgacggtct	CRISPR spacer
actggggcgtcgagcacatcgacggctacggtca	Protospacer
*  *  . .**** ************ ******

20. spacer 3.3|1625525|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 10, identity: 0.706

aaggccaaatcgaccacatcgacggcgacggtct	CRISPR spacer
gtcgcggcctcgaccacagcgaccgcgacggtcg	Protospacer
.  ** .  ********* **** *********

21. spacer 3.3|1625525|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013454 (Burkholderia vietnamiensis strain MSMB608WGS plasmid pMSMB608, complete sequence) position: , mismatch: 10, identity: 0.706

aaggccaaatcgaccacatcgacggcgacggtct	CRISPR spacer
caaacgaaaccggccacatcgacggcgacgcctc	Protospacer
 *..* ***.**.***************** ...

22. spacer 3.3|1625525|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to NC_016165 (Rhodobacter phage RcapMu, complete genome) position: , mismatch: 10, identity: 0.706

aaggccaaatcgaccacatcgacggcgacggtct	CRISPR spacer
gtcgcggcctcgaccacagcgaccgcgacggtcg	Protospacer
.  ** .  ********* **** *********

23. spacer 3.4|1625591|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 10, identity: 0.706

gtgatgtcgcgttccggcacgacgcgctcaaaaa	CRISPR spacer
gtgatgtcgagttccggcaccacggaattgctga	Protospacer
********* ********** *** . *..  .*

24. spacer 3.4|1625591|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015881 (Ensifer adhaerens strain Casida A plasmid pCasidaAA, complete sequence) position: , mismatch: 10, identity: 0.706

gtgatgtcgcgttccggcacgacgcgctcaaaaa	CRISPR spacer
gtgatgtcgagttccggcaccacggaattgctga	Protospacer
********* ********** *** . *..  .*

25. spacer 3.40|1627985|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP044049 (Klebsiella variicola strain FDAARGOS_627 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

aaaaagcgacatagaagagcgcatttatggagac	CRISPR spacer
gctccccgtgatagaagagcgcatttccggagac	Protospacer
.     **  **************** .******

26. spacer 3.76|1630383|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NC_011961 (Thermomicrobium roseum DSM 5159 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

catgcagaccacctgcgctgacgagcaggaagca	CRISPR spacer
ctcctcgactacctgcgctgacgagcgggaaagg	Protospacer
* . . ***.****************.****. .

27. spacer 3.95|1631652|33|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 10, identity: 0.697

ttctgtcgccggcggcgctcaggtgctgcagat	CRISPR spacer
catgacggccggcggcgcacaggtgctgctgaa	Protospacer
. . .. *********** ********** **

28. spacer 3.95|1631652|33|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP054618 (Azospirillum oryzae strain KACC 14407 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.697

ttctgtcgccggcggcgctcaggtgctgcagat	CRISPR spacer
ggcggtggccggcggcgctcaggcgctgggcca	Protospacer
  * ** ****************.**** .

29. spacer 3.112|1632779|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP028969 (Aminobacter sp. MSH1 plasmid pUSP1, complete sequence) position: , mismatch: 10, identity: 0.706

cgatggcgcaggccaaaaccgttgaggctcaagc	CRISPR spacer
acttttcccaggccaaaaccgttgagtcacaaat	Protospacer
   *  * ****************** * ***..

30. spacer 3.112|1632779|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP026266 (Aminobacter sp. MSH1 plasmid pAM01, complete sequence) position: , mismatch: 10, identity: 0.706

cgatggcgcaggccaaaaccgttgaggctcaagc	CRISPR spacer
acttttcccaggccaaaaccgttgagtcacaaat	Protospacer
   *  * ****************** * ***..

31. spacer 3.4|1625591|34|NC_008639|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019603 (Croceicoccus marinus strain E4A9 plasmid pCME4A9I, complete sequence) position: , mismatch: 11, identity: 0.676

gtgatgtcgcgttccggcacgacgcgctcaaaaa	CRISPR spacer
acgatgtcgcgtttcggcccgacgcgcagcgtgt	Protospacer
..***********.**** ********   . .

32. spacer 3.70|1629984|35|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NC_012521 (Rhodococcus opacus B4 plasmid pROB02, complete sequence) position: , mismatch: 11, identity: 0.686

caaccgggatgtgcagtccgtgcgagatcagctta	CRISPR spacer
aatccgggatgtccagtccgtgcgtgatggcgagg	Protospacer
 * ********* *********** *** .    .

33. spacer 3.78|1630516|36|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP017077 (Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence) position: , mismatch: 11, identity: 0.694

gcatgtgtcgaacagatcaccatcgaagagaaccgt	CRISPR spacer
ttccgcttcgagcagatcatcatcgaagagaacatg	Protospacer
 . .*. ****.*******.*************

34. spacer 3.82|1630785|34|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to KY653116 (Staphylococcus phage IME1318_01, complete genome) position: , mismatch: 11, identity: 0.676

ggaggacatcttcatcaattcttcatctgtgatt	CRISPR spacer
taacttagccttcatcaattcttcatctttaata	Protospacer
 .*    ..******************* *.**

35. spacer 3.94|1631585|35|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP007794 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p1, complete sequence) position: , mismatch: 11, identity: 0.686

tgcgggagcagcttgatggcggtgacgttttcgac	CRISPR spacer
accggcagcagctcgatggcggtgacgccaagctc	Protospacer
  *** *******.*************..     *

36. spacer 3.94|1631585|35|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 11, identity: 0.686

tgcgggagcagcttgatggcggtgacgttttcgac	CRISPR spacer
accggcagcagctcgatggcggtgacgcccaattc	Protospacer
  *** *******.*************...    *

37. spacer 3.94|1631585|35|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 11, identity: 0.686

tgcgggagcagcttgatggcggtgacgttttcgac	CRISPR spacer
accggcagcagctcgatggcggtgacgcccagctc	Protospacer
  *** *******.*************...    *

38. spacer 3.70|1629984|35|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP046574 (Rhodococcus sp. WAY2 plasmid pRWAY02, complete sequence) position: , mismatch: 12, identity: 0.657

caaccgggatgtgcagtccgtgcgagatcagctta	CRISPR spacer
attccgggatgtccagtccgtgcgtgatggcgagg	Protospacer
   ********* *********** *** .    .

39. spacer 3.70|1629984|35|NC_008639|CRT,PILER-CR,CRISPRCasFinder matches to NC_008271 (Rhodococcus jostii RHA1 plasmid pRHL3, complete sequence) position: , mismatch: 12, identity: 0.657

caaccgggatgtgcagtccgtgcgagatcagctta	CRISPR spacer
agtccgggatgtccagtccgtgcgtgatggcgagg	Protospacer
 . ********* *********** *** .    .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5092 : 49020

Escherichia_phage(14.29%)

transposase,protease,tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011743925.1\|5092_6328_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_011743927.1\|6780_8352_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_150081139.1\|8435_9194_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_011743929.1\|9404_9935_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011743930.1\|10368_11061_-\|transposase	transposase	NA	NA	NA	NA
WP_011743931.1\|11057_11600_-\|transposase	transposase	NA	NA	NA	NA
WP_011743932.1\|11703_12462_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_150081035.1\|12480_12636_-	hypothetical protein	NA	NA	NA	NA
WP_011743933.1\|12685_14092_+\|transposase	IS1380-like element ISCph6 family transposase	NA	NA	NA	NA
WP_049751716.1\|15848_16067_+	hypothetical protein	NA	NA	NA	NA
WP_011743933.1\|16158_17565_+\|transposase	IS1380-like element ISCph6 family transposase	NA	NA	NA	NA
WP_011743936.1\|18029_18560_+	hypothetical protein	NA	NA	NA	NA
WP_041467109.1\|18556_18973_+	hypothetical protein	NA	NA	NA	NA
WP_150081036.1\|19872_20707_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_011743937.1\|20844_22209_-\|transposase	IS110 family transposase	Q9JMN8	Wolbachia_phage	2.6e-118	48.4
WP_011743938.1\|23042_24266_-	FprA family A-type flavoprotein	NA	NA	NA	NA
WP_011743939.1\|24549_26940_-	ribonuclease H-like domain-containing protein	A0A2I6UGB2	Salinibacter_virus	2.3e-146	39.8
WP_011743940.1\|27337_29203_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_041467113.1\|29627_30065_+	thiosulfate-binding protein SoxY	NA	NA	NA	NA
WP_011743942.1\|30106_30403_+	thiosulfate oxidation carrier complex protein SoxZ	NA	NA	NA	NA
WP_011743943.1\|30478_30859_+	sulfide dehydrogenase (flavocytochrome), cytochrome c subunit	NA	NA	NA	NA
WP_011743944.1\|30873_32166_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011743945.1\|32394_34254_+	protein translocase subunit SecD	NA	NA	NA	NA
WP_011743946.1\|34276_35212_+	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	3.1e-38	37.3
WP_011743947.1\|35468_36785_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_011743948.1\|36773_38705_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	9.1e-141	47.1
WP_011743949.1\|38786_39170_-	YraN family protein	NA	NA	NA	NA
WP_081428199.1\|39179_39803_-	ribonuclease HII	G9E3X7	Emiliania_huxleyi_virus	1.3e-27	43.1
WP_150081037.1\|39829_40096_-	hypothetical protein	NA	NA	NA	NA
WP_011743952.1\|40726_42424_+	ribonuclease E/G	NA	NA	NA	NA
WP_011743953.1\|42440_43304_+	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	NA	NA	NA	NA
WP_049751717.1\|43366_45067_+	S41 family peptidase	NA	NA	NA	NA
WP_011743955.1\|45058_45778_-	DUF3593 domain-containing protein	NA	NA	NA	NA
WP_011743956.1\|45809_46952_-	geranylgeranyl diphosphate reductase	NA	NA	NA	NA
WP_011743957.1\|46992_48462_-\|tRNA	glycine--tRNA ligase	A0A2I2L3K8	Orpheovirus	4.6e-36	27.5
WP_011743958.1\|48702_49020_-\|protease	ATP-dependent Clp protease adaptor ClpS	NA	NA	NA	NA

DBSCAN-SWA_2

273032 : 311354

Klosneuvirus(33.33%)

transposase,integrase,protease,tRNA

attL 281591:281633|attR 298952:298994

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011744150.1\|273032_275699_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	5.0e-89	41.1
WP_011744151.1\|275722_277081_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011744152.1\|277186_277681_+	ferredoxin family protein	NA	NA	NA	NA
WP_011744153.1\|277732_278035_+	ferredoxin family protein	NA	NA	NA	NA
WP_011744154.1\|278090_279047_-	HipA domain-containing protein	NA	NA	NA	NA
WP_011744155.1\|279051_279375_-	HipA N-terminal domain-containing protein	NA	NA	NA	NA
WP_011744156.1\|279378_279585_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011744157.1\|279919_281137_-	phosphoserine phosphatase SerB	NA	NA	NA	NA
WP_049751720.1\|281203_281476_+	hypothetical protein	NA	NA	NA	NA
281591:281633	attL	NA	NA	NA	NA
WP_011744158.1\|283295_283586_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_011744159.1\|283582_283807_-	addiction module protein	NA	NA	NA	NA
WP_011744160.1\|283849_285070_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_081428200.1\|286941_287211_+	hypothetical protein	NA	NA	NA	NA
WP_011744162.1\|287224_288241_+\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	2.3e-63	42.9
WP_011744163.1\|288423_288852_+	hypothetical protein	NA	NA	NA	NA
WP_011744164.1\|289089_289329_+	hypothetical protein	NA	NA	NA	NA
WP_011744165.1\|289481_289934_+	hypothetical protein	NA	NA	NA	NA
WP_011743933.1\|290523_291930_-\|transposase	IS1380-like element ISCph6 family transposase	NA	NA	NA	NA
WP_011744166.1\|292107_292848_+	hypothetical protein	NA	NA	NA	NA
WP_041467467.1\|292952_293210_+	DUF4160 domain-containing protein	NA	NA	NA	NA
WP_011744168.1\|293206_293464_+	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_150081045.1\|293771_294203_+	hypothetical protein	NA	NA	NA	NA
WP_150081046.1\|294567_295170_+	hypothetical protein	NA	NA	NA	NA
WP_011744171.1\|295417_296188_+	hypothetical protein	NA	NA	NA	NA
WP_011743933.1\|296447_297854_-\|transposase	IS1380-like element ISCph6 family transposase	NA	NA	NA	NA
WP_011744172.1\|298717_298981_+	hypothetical protein	NA	NA	NA	NA
WP_011744173.1\|299401_300049_+	hypothetical protein	NA	NA	NA	NA
298952:298994	attR	NA	NA	NA	NA
WP_041467139.1\|300315_301065_+	hypothetical protein	NA	NA	NA	NA
WP_011743927.1\|301159_302731_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_150081139.1\|302814_303573_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_190271900.1\|303731_303902_+	hypothetical protein	NA	NA	NA	NA
WP_011744175.1\|304389_305262_+	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_011744176.1\|305550_306744_+	hypothetical protein	NA	NA	NA	NA
WP_011744177.1\|306835_307525_+	hypothetical protein	NA	NA	NA	NA
WP_011744178.1\|307600_308236_+	hypothetical protein	NA	NA	NA	NA
WP_150081048.1\|309205_309961_+	hypothetical protein	NA	NA	NA	NA
WP_011744180.1\|310484_311354_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_3

350469 : 365126

Leptospira_phage(33.33%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011744218.1\|350469_351522_+\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	6.9e-42	31.3
WP_011744219.1\|351496_353752_+	Fe(2+) transporter permease subunit FeoB	NA	NA	NA	NA
WP_041467144.1\|353821_354046_+	FeoC-like transcriptional regulator	NA	NA	NA	NA
WP_011744221.1\|354157_354511_+	hypothetical protein	NA	NA	NA	NA
WP_011744222.1\|354555_355062_+	flavodoxin	NA	NA	NA	NA
WP_041467145.1\|355314_356934_+\|transposase	IS1634 family transposase	NA	NA	NA	NA
WP_081428202.1\|357016_357337_+	flavodoxin domain-containing protein	NA	NA	NA	NA
WP_081428203.1\|357375_357720_+	ferritin	NA	NA	NA	NA
WP_011743927.1\|357831_359403_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_150081139.1\|359486_360245_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_011744224.1\|360565_361108_+\|transposase	transposase	NA	NA	NA	NA
WP_011744225.1\|361104_361797_+\|transposase	transposase	NA	NA	NA	NA
WP_011744226.1\|361922_362387_-	hypothetical protein	NA	NA	NA	NA
WP_011744227.1\|362561_365126_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	4.0e-128	35.3

DBSCAN-SWA_4

1619046 : 1686454

Escherichia_phage(37.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011745269.1\|1619046_1620012_-\|transposase	transposase	NA	NA	NA	NA
WP_011745270.1\|1620312_1620642_+	DUF4258 domain-containing protein	NA	NA	NA	NA
WP_041467258.1\|1620638_1620851_+	YgiT-type zinc finger protein	NA	NA	NA	NA
WP_011745271.1\|1620981_1621947_-\|transposase	transposase	NA	NA	NA	NA
WP_041467605.1\|1622858_1623599_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.0e-43	42.2
WP_011745273.1\|1623619_1625194_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	8.2e-07	26.3
WP_011745274.1\|1633226_1633517_-	CRISPR-associated endonuclease Cas2	NA	NA	NA	NA
WP_011745275.1\|1633520_1634552_-	type I-C CRISPR-associated endonuclease Cas1	NA	NA	NA	NA
WP_011745276.1\|1634548_1635193_-	CRISPR-associated protein Cas4	NA	NA	NA	NA
WP_011745277.1\|1635195_1636296_-	type I-C CRISPR-associated protein Cas7/Csd2	NA	NA	NA	NA
WP_011745278.1\|1636336_1638061_-	type I-C CRISPR-associated protein Cas8c/Csd1	NA	NA	NA	NA
WP_011745279.1\|1638057_1638771_-	type I-C CRISPR-associated protein Cas5	NA	NA	NA	NA
WP_011745280.1\|1638793_1640797_-	CRISPR-associated helicase Cas3'	NA	NA	NA	NA
WP_011745281.1\|1640783_1641035_-	CRISPR-associated endonuclease Cas3''	NA	NA	NA	NA
WP_011745282.1\|1641027_1642041_-	WYL domain-containing protein	NA	NA	NA	NA
WP_041467608.1\|1643365_1643575_+	type II toxin-antitoxin system HicB family antitoxin	NA	NA	NA	NA
WP_011745285.1\|1643571_1643784_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_011745286.1\|1643957_1644170_-	hypothetical protein	NA	NA	NA	NA
WP_011745287.1\|1644567_1645743_-	hypothetical protein	NA	NA	NA	NA
WP_011745288.1\|1645739_1649105_-	hypothetical protein	NA	NA	NA	NA
WP_011745289.1\|1649097_1649733_-	DUF4194 domain-containing protein	NA	NA	NA	NA
WP_011745290.1\|1649729_1651178_-	DUF3375 domain-containing protein	NA	NA	NA	NA
WP_150081079.1\|1651773_1652337_-	hypothetical protein	NA	NA	NA	NA
WP_011745293.1\|1652733_1653735_+	chlorophyll synthase ChlG	NA	NA	NA	NA
WP_011745294.1\|1653734_1654139_+	glycosyltransferase family 2 protein	A0A2P1ELT8	Moumouvirus	6.5e-09	34.0
WP_150081139.1\|1654120_1654879_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_011743927.1\|1654962_1656534_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_011745295.1\|1656664_1656970_+	hypothetical protein	NA	NA	NA	NA
WP_011745296.1\|1656977_1657526_+	TIGR00730 family Rossman fold protein	A0A1G5S9X4	Enterococcus_phage	1.0e-17	39.9
WP_011745298.1\|1658114_1658918_+	zinc transporter ZupT	NA	NA	NA	NA
WP_011745299.1\|1659063_1659432_-	NifB/NifX family molybdenum-iron cluster-binding protein	NA	NA	NA	NA
WP_011745300.1\|1659428_1660115_-	DUF134 domain-containing protein	NA	NA	NA	NA
WP_011745301.1\|1660234_1661236_-	bifunctional methionine sulfoxide reductase B/A protein	NA	NA	NA	NA
WP_011745302.1\|1661426_1663589_+	thioredoxin domain-containing protein	NA	NA	NA	NA
WP_011745303.1\|1663560_1663788_-	hypothetical protein	NA	NA	NA	NA
WP_011745304.1\|1664067_1664352_-	hypothetical protein	NA	NA	NA	NA
WP_011745305.1\|1664460_1665261_-	ferredoxin--NADP reductase	NA	NA	NA	NA
WP_011745306.1\|1665336_1665795_-	SRPBCC domain-containing protein	NA	NA	NA	NA
WP_011745307.1\|1665898_1666567_-	DUF2461 domain-containing protein	NA	NA	NA	NA
WP_011745308.1\|1666750_1666945_-	hypothetical protein	NA	NA	NA	NA
WP_011745309.1\|1667072_1667507_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_011745310.1\|1667963_1668530_-	nitroreductase family protein	NA	NA	NA	NA
WP_011745311.1\|1668613_1669015_-	PaaI family thioesterase	NA	NA	NA	NA
WP_011745312.1\|1669237_1670038_-	hypothetical protein	NA	NA	NA	NA
WP_011745313.1\|1670296_1671316_+	SEC-C domain-containing protein	NA	NA	NA	NA
WP_190271867.1\|1671686_1671827_+	hypothetical protein	NA	NA	NA	NA
WP_011745314.1\|1671832_1672252_-	hypothetical protein	NA	NA	NA	NA
WP_190271868.1\|1672248_1673355_-	Tat pathway signal protein	NA	NA	NA	NA
WP_041467263.1\|1673502_1673772_-	hypothetical protein	NA	NA	NA	NA
WP_011745317.1\|1673985_1674765_-	hypothetical protein	NA	NA	NA	NA
WP_150081080.1\|1677083_1678238_+	hypothetical protein	NA	NA	NA	NA
WP_011745321.1\|1678622_1679879_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	6.1e-29	31.0
WP_011745273.1\|1680673_1682248_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	8.2e-07	26.3
WP_041467605.1\|1682268_1683009_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.0e-43	42.2
WP_011745324.1\|1685482_1686454_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_5

1730860 : 1796933

uncultured_phage(10.0%)

protease,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011745356.1\|1730860_1731562_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_011745357.1\|1731603_1732107_-	16S rRNA processing protein RimM	NA	NA	NA	NA
WP_011745358.1\|1732128_1732536_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_011745359.1\|1732575_1733925_-	signal recognition particle protein	D6PHS7	uncultured_phage	2.6e-09	26.0
WP_011745360.1\|1734104_1735088_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	8.2e-13	26.1
WP_011745361.1\|1735059_1735698_-	START domain-containing protein	NA	NA	NA	NA
WP_011745362.1\|1735747_1736404_-	cyclase	NA	NA	NA	NA
WP_011745363.1\|1736449_1738105_-	S41 family peptidase	A0A0R6PIZ1	Moraxella_phage	3.3e-22	27.1
WP_011745364.1\|1738962_1739445_-	RidA family protein	NA	NA	NA	NA
WP_150081082.1\|1739781_1740429_+	thiamine phosphate synthase	NA	NA	NA	NA
WP_011745366.1\|1740425_1741046_+	thiamine phosphate synthase	NA	NA	NA	NA
WP_011745367.1\|1741049_1741865_+	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_011745368.1\|1741869_1743207_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	3.9e-82	37.8
WP_011745369.1\|1743491_1744340_-	hypothetical protein	NA	NA	NA	NA
WP_011745370.1\|1744321_1745026_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_011745371.1\|1745113_1746625_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	8.9e-51	37.2
WP_011745372.1\|1746649_1747714_-	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_011745373.1\|1748155_1749247_+	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	NA	NA	NA	NA
WP_011745374.1\|1749263_1750037_+	hypothetical protein	NA	NA	NA	NA
WP_011745375.1\|1750050_1750707_+	adenylate kinase	NA	NA	NA	NA
WP_011745376.1\|1750775_1753208_+	primosomal protein N'	NA	NA	NA	NA
WP_011745377.1\|1753301_1753802_+	DoxX family membrane protein	NA	NA	NA	NA
WP_041467625.1\|1753828_1754293_-	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_041467626.1\|1754356_1755838_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A2H5BJT2	Erwinia_phage	9.1e-40	29.5
WP_041467627.1\|1755898_1756447_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_011745381.1\|1756463_1757918_-	RNA polymerase factor sigma-54	NA	NA	NA	NA
WP_011745382.1\|1757917_1758490_-	DUF3109 family protein	NA	NA	NA	NA
WP_011745383.1\|1758924_1761396_-	PAS domain S-box protein	NA	NA	NA	NA
WP_190271869.1\|1762027_1762351_+	DUF2141 domain-containing protein	NA	NA	NA	NA
WP_011745385.1\|1762392_1762593_+	YnbE family lipoprotein	NA	NA	NA	NA
WP_011745386.1\|1762609_1762963_+	YdbL family protein	NA	NA	NA	NA
WP_011745387.1\|1762986_1765662_+	YdbH domain-containing protein	NA	NA	NA	NA
WP_011745388.1\|1765664_1766129_-	hypothetical protein	NA	NA	NA	NA
WP_190271870.1\|1766141_1766936_-	hypothetical protein	NA	NA	NA	NA
WP_150081139.1\|1767095_1767854_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_011745137.1\|1767937_1769509_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_041467269.1\|1769620_1770220_-	hypothetical protein	NA	NA	NA	NA
WP_041467270.1\|1770227_1770497_-	hypothetical protein	NA	NA	NA	NA
WP_011745391.1\|1770571_1771096_+	DinB family protein	NA	NA	NA	NA
WP_041467271.1\|1771351_1772284_+	hypothetical protein	NA	NA	NA	NA
WP_150081208.1\|1772303_1773623_-	aminoacetone oxidase family FAD-binding enzyme	A0A2H4PQX1	Staphylococcus_phage	7.6e-14	37.8
WP_011745394.1\|1773677_1775114_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_011745395.1\|1775154_1778340_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_150081083.1\|1778449_1779595_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_011745397.1\|1779676_1780180_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	7.9e-20	39.5
WP_049751751.1\|1780577_1782347_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_011745399.1\|1782995_1784075_-	alkene reductase	NA	NA	NA	NA
WP_011745401.1\|1784777_1785647_+	UbiA family prenyltransferase	NA	NA	NA	NA
WP_011745402.1\|1786142_1787732_+	rubredoxin	NA	NA	NA	NA
WP_011745403.1\|1787792_1788293_+	rubrerythrin family protein	NA	NA	NA	NA
WP_011745404.1\|1788521_1788938_+	hypothetical protein	NA	NA	NA	NA
WP_011745405.1\|1789423_1790182_+\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_011745406.1\|1790475_1791270_+	sterol desaturase family protein	NA	NA	NA	NA
WP_011745407.1\|1791274_1791739_-	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_011745408.1\|1791725_1792385_-	3'-5' exonuclease	A0A0A7RWA3	Clostridium_phage	9.6e-26	40.0
WP_041467631.1\|1792934_1793840_-	protein-glutamate O-methyltransferase family protein	NA	NA	NA	NA
WP_011745410.1\|1794071_1795022_-\|transposase	transposase	NA	NA	NA	NA
WP_190271871.1\|1795399_1795834_-	hypothetical protein	NA	NA	NA	NA
WP_011745412.1\|1796057_1796933_-\|protease	protease HtpX	NA	NA	NA	NA

DBSCAN-SWA_6

2231510 : 2286033

uncultured_virus(16.67%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011745748.1\|2231510_2233085_+\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	1.1e-06	26.3
WP_041467605.1\|2233105_2233846_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.0e-43	42.2
WP_150081105.1\|2234868_2235339_-	hypothetical protein	NA	NA	NA	NA
WP_081428234.1\|2235793_2236243_-\|protease	protease inhibitor I42 family protein	NA	NA	NA	NA
WP_011745750.1\|2236264_2237101_-	copper resistance protein NlpE N-terminal domain-containing protein	NA	NA	NA	NA
WP_011745751.1\|2237622_2238033_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_041467696.1\|2238189_2238723_+	SRPBCC family protein	NA	NA	NA	NA
WP_041467697.1\|2238786_2239830_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_011745754.1\|2239783_2240863_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_011745755.1\|2240875_2241679_-	tryptophan synthase subunit alpha	NA	NA	NA	NA
WP_011745756.1\|2241696_2242383_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_011745757.1\|2242471_2243152_-	7-cyano-7-deazaguanine synthase QueC	R4TAI3	Halovirus	7.1e-24	31.3
WP_011745758.1\|2243328_2244972_-	chaperonin GroEL	A0A240F779	uncultured_virus	2.8e-175	62.5
WP_011745759.1\|2245018_2245306_-	co-chaperone GroES	A0A221S3C8	uncultured_virus	4.5e-20	55.4
WP_011745760.1\|2245493_2245772_+	hypothetical protein	NA	NA	NA	NA
WP_011745761.1\|2245793_2248646_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	3.4e-221	44.0
WP_011745762.1\|2248707_2249133_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_041467699.1\|2249264_2250137_+	alpha/beta fold hydrolase	G9E3U1	Emiliania_huxleyi_virus	2.9e-06	36.2
WP_011745764.1\|2250148_2252875_-	LPS-assembly protein LptD	NA	NA	NA	NA
WP_011745765.1\|2253048_2254248_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_011745766.1\|2255468_2255945_+	DUF1566 domain-containing protein	NA	NA	NA	NA
WP_011745768.1\|2258651_2258846_-	hypothetical protein	NA	NA	NA	NA
WP_011745769.1\|2259034_2260270_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_011745771.1\|2260487_2261594_-	HigA family addiction module antidote protein	A0A075BTZ7	Microcystis_phage	1.5e-10	46.8
WP_011745772.1\|2261609_2261945_-	hypothetical protein	NA	NA	NA	NA
WP_011745773.1\|2262003_2264907_-	DEAD/DEAH box helicase	A0A2H4J643	uncultured_Caudovirales_phage	1.1e-230	44.4
WP_011745776.1\|2268057_2269293_-	quorum-sensing autoinducer CAI-1 synthase	NA	NA	NA	NA
WP_011745777.1\|2269699_2272255_+	response regulator	A0A1V0SGX0	Hokovirus	3.6e-20	23.5
WP_011745778.1\|2272567_2273203_-	flavodoxin family protein	NA	NA	NA	NA
WP_011745779.1\|2273506_2274220_+	type 1 glutamine amidotransferase	NA	NA	NA	NA
WP_150081106.1\|2274266_2275634_+	deoxyribodipyrimidine photo-lyase	Q4KT08	Chrysodeixis_chalcites_nucleopolyhedrovirus	8.2e-120	46.0
WP_011745781.1\|2275675_2278051_-	ribonuclease R	Q0GXV6	Lactococcus_phage	6.5e-64	33.4
WP_011745782.1\|2278386_2278860_-	transcriptional repressor	NA	NA	NA	NA
WP_041467338.1\|2279076_2279430_+	hypothetical protein	NA	NA	NA	NA
WP_011745784.1\|2279585_2280263_+	peroxiredoxin	NA	NA	NA	NA
WP_011745785.1\|2281227_2282829_+	indolepyruvate ferredoxin oxidoreductase	NA	NA	NA	NA
WP_011745786.1\|2282834_2283431_+	indolepyruvate oxidoreductase subunit beta	NA	NA	NA	NA
WP_011745787.1\|2283427_2284729_+	phenylacetate--CoA ligase	NA	NA	NA	NA
WP_041467304.1\|2284801_2285344_+\|transposase	transposase	NA	NA	NA	NA
WP_011745578.1\|2285340_2286033_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_7

2304394 : 2315234

Escherichia_phage(42.86%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011745808.1\|2304394_2307655_-\|tRNA	isoleucine--tRNA ligase	A0A2I2L3Y0	Orpheovirus	2.3e-168	34.3
WP_011745809.1\|2307831_2308044_-	hypothetical protein	NA	NA	NA	NA
WP_011745810.1\|2308247_2309231_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	6.9e-44	36.0
WP_011745811.1\|2309404_2309848_-	hypothetical protein	NA	NA	NA	NA
WP_011745812.1\|2310006_2311080_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	2.7e-86	51.6
WP_011745813.1\|2311120_2311993_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	5.2e-35	37.5
WP_011745814.1\|2312126_2312708_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	3.4e-43	56.3
WP_011745815.1\|2312808_2313708_-	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	2.0e-106	63.5
WP_011745816.1\|2313881_2314391_-	LptE family protein	NA	NA	NA	NA
WP_011745817.1\|2314409_2315234_-	SDR family oxidoreductase	A0A2P0VP75	Tetraselmis_virus	1.1e-15	31.8

DBSCAN-SWA_8

2447635 : 2516346

Escherichia_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011743927.1\|2447635_2449207_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_150081139.1\|2449290_2450049_+	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_150081109.1\|2450098_2451255_-\|transposase	IS3 family transposase	Q6H9S3	Enterobacteria_phage	2.1e-23	30.0
WP_011745925.1\|2451740_2452172_-	thiol-disulfide oxidoreductase DCC family protein	NA	NA	NA	NA
WP_190271883.1\|2452250_2452388_-	hypothetical protein	NA	NA	NA	NA
WP_011745926.1\|2452598_2453885_+	ATP-binding protein	NA	NA	NA	NA
WP_041467360.1\|2453996_2454206_-	DUF2283 domain-containing protein	NA	NA	NA	NA
WP_041467361.1\|2454638_2455070_-	hypothetical protein	NA	NA	NA	NA
WP_011745929.1\|2456147_2456372_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_190271941.1\|2456427_2456577_-	hypothetical protein	NA	NA	NA	NA
WP_011745930.1\|2456951_2457737_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_011745931.1\|2457762_2458089_-	DsrE family protein	NA	NA	NA	NA
WP_011745932.1\|2459283_2459949_+	metalloregulator ArsR/SmtB family transcription factor	NA	NA	NA	NA
WP_049751766.1\|2460068_2460722_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_041467719.1\|2460736_2461066_+	CGGC domain-containing protein	NA	NA	NA	NA
WP_011745935.1\|2461191_2461656_-	hypothetical protein	NA	NA	NA	NA
WP_011745936.1\|2461704_2461983_-	metal/formaldehyde-sensitive transcriptional repressor	NA	NA	NA	NA
WP_011745937.1\|2462269_2463271_+\|transposase	transposase	NA	NA	NA	NA
WP_011745938.1\|2466176_2467223_+\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	4.3e-44	36.1
WP_011745939.1\|2467401_2470149_-	hypothetical protein	NA	NA	NA	NA
WP_011745940.1\|2471705_2473304_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_011745941.1\|2474316_2474991_-	S-adenosylmethionine-binding protein	A0A076YNT4	Mesorhizobium_phage	1.4e-72	68.3
WP_011745943.1\|2476462_2477509_+\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	4.3e-44	36.1
WP_011745944.1\|2477555_2478968_-	DUF2252 domain-containing protein	NA	NA	NA	NA
WP_011745945.1\|2479077_2479548_-	SRPBCC family protein	NA	NA	NA	NA
WP_011745946.1\|2479551_2481243_-	L,D-transpeptidase family protein	NA	NA	NA	NA
WP_150081228.1\|2481242_2481923_-	murein L,D-transpeptidase catalytic domain family protein	NA	NA	NA	NA
WP_011745949.1\|2482889_2483618_-	SIMPL domain-containing protein	NA	NA	NA	NA
WP_011745950.1\|2483666_2484323_-	hypothetical protein	NA	NA	NA	NA
WP_011745951.1\|2484640_2485279_-	YukJ family protein	NA	NA	NA	NA
WP_011745952.1\|2485519_2487535_+	transketolase	NA	NA	NA	NA
WP_011745953.1\|2487549_2488368_+	6-phosphogluconolactonase	NA	NA	NA	NA
WP_011745954.1\|2488345_2489785_-	glucose-6-phosphate dehydrogenase	M4SIY3	Cyanophage	7.4e-79	38.1
WP_011745955.1\|2489797_2490697_-	decarboxylating 6-phosphogluconate dehydrogenase	A0A222YX62	Synechococcus_phage	7.9e-55	38.2
WP_011745956.1\|2490829_2493787_-	response regulator	A0A1V0SGX0	Hokovirus	1.2e-51	29.6
WP_011745957.1\|2493815_2495018_-	FIST C-terminal domain-containing protein	NA	NA	NA	NA
WP_011745958.1\|2495265_2495985_-	SIMPL domain-containing protein	NA	NA	NA	NA
WP_041467724.1\|2496128_2497268_-	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_011745960.1\|2497410_2497875_-	YbaK/EbsC family protein	NA	NA	NA	NA
WP_011745961.1\|2498033_2498807_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_011745962.1\|2498867_2500256_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_011745963.1\|2500471_2502283_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.9e-68	34.8
WP_011745964.1\|2502572_2503322_+	TerC family protein	A0A0R6PEZ3	Moraxella_phage	4.7e-45	46.0
WP_011745965.1\|2503546_2504389_+	universal stress protein	NA	NA	NA	NA
WP_150081110.1\|2504425_2504767_-	hypothetical protein	NA	NA	NA	NA
WP_011745967.1\|2504875_2505682_-	RNA methyltransferase	NA	NA	NA	NA
WP_011745968.1\|2505678_2506536_-	hypothetical protein	NA	NA	NA	NA
WP_011745969.1\|2506761_2508024_+	U32 family peptidase	Q6DW11	Phage_TP	1.5e-27	28.2
WP_011745970.1\|2508113_2509193_+	4Fe-4S dicluster domain-containing protein	NA	NA	NA	NA
WP_011745971.1\|2509246_2510071_+	FAD/NAD(P)-binding protein	NA	NA	NA	NA
WP_011745972.1\|2510081_2510846_+	NADH ubiquinone oxidoreductase	NA	NA	NA	NA
WP_011745973.1\|2510835_2512110_+	Ni/Fe hydrogenase subunit alpha	NA	NA	NA	NA
WP_011745974.1\|2512177_2512357_+	hypothetical protein	NA	NA	NA	NA
WP_190271884.1\|2512551_2512974_-	hypothetical protein	NA	NA	NA	NA
WP_081428238.1\|2513409_2513730_-	hypothetical protein	NA	NA	NA	NA
WP_150081139.1\|2513932_2514691_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_011745977.1\|2514774_2516346_-\|transposase	IS21 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

2529013 : 2575127

Escherichia_phage(40.0%)

transposase,integrase

attL 2541526:2541585|attR 2574088:2574328

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041467370.1\|2529013_2529247_-\|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_011745996.1\|2529420_2530368_-	CoA ester lyase	NA	NA	NA	NA
WP_011745997.1\|2530595_2530871_-	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_011745998.1\|2530851_2530986_-	DUF4160 domain-containing protein	NA	NA	NA	NA
WP_081428239.1\|2531316_2531439_-	DUF4160 domain-containing protein	NA	NA	NA	NA
WP_190271885.1\|2531551_2531713_+	hypothetical protein	NA	NA	NA	NA
WP_150081112.1\|2532268_2532886_+	hypothetical protein	NA	NA	NA	NA
WP_150081113.1\|2533236_2534259_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_011746002.1\|2534261_2535245_-\|transposase	transposase	NA	NA	NA	NA
WP_190271886.1\|2536691_2537900_+	ATP-binding protein	V9QJ85	Oenococcus_phage	4.8e-07	25.9
WP_011746006.1\|2537899_2538577_+	RloB domain-containing protein	NA	NA	NA	NA
WP_150081139.1\|2538875_2539634_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_011743927.1\|2539717_2541289_-\|transposase	IS21 family transposase	NA	NA	NA	NA
2541526:2541585	attL	NA	NA	NA	NA
WP_041467372.1\|2541599_2541848_-	hypothetical protein	NA	NA	NA	NA
WP_011746007.1\|2541844_2542810_-\|transposase	transposase	NA	NA	NA	NA
WP_011746008.1\|2542906_2544001_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	4.6e-25	29.7
WP_011746009.1\|2544293_2544494_-	hypothetical protein	NA	NA	NA	NA
WP_011746011.1\|2545106_2546090_-\|transposase	transposase	NA	NA	NA	NA
WP_011746012.1\|2546157_2546934_-	hypothetical protein	NA	NA	NA	NA
WP_041467374.1\|2547178_2547658_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_150081114.1\|2547654_2548674_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_041467737.1\|2548755_2548980_+	DUF433 domain-containing protein	NA	NA	NA	NA
WP_011746016.1\|2549194_2549407_-	hypothetical protein	NA	NA	NA	NA
WP_011746018.1\|2549928_2550417_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011746019.1\|2550664_2551948_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_011746020.1\|2552271_2554404_-	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_011746021.1\|2554403_2555717_-	ATP-binding protein	NA	NA	NA	NA
WP_011746022.1\|2555713_2557687_-	hypothetical protein	NA	NA	NA	NA
WP_081428256.1\|2557990_2558185_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_041467739.1\|2558386_2558743_-	SUMF1/EgtB/PvdO family nonheme iron enzyme	NA	NA	NA	NA
WP_011746024.1\|2559135_2559921_+	hypothetical protein	NA	NA	NA	NA
WP_011746025.1\|2559971_2560937_-\|transposase	transposase	NA	NA	NA	NA
WP_041467377.1\|2561874_2562363_+	hypothetical protein	NA	NA	NA	NA
WP_190271943.1\|2562510_2562660_-	hypothetical protein	NA	NA	NA	NA
WP_011746027.1\|2562686_2563667_-	uracil-DNA glycosylase	NA	NA	NA	NA
WP_011746028.1\|2564076_2565042_-\|transposase	transposase	NA	NA	NA	NA
WP_041467605.1\|2565753_2566494_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	2.0e-43	42.2
WP_011745273.1\|2566514_2568089_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	8.2e-07	26.3
WP_081428257.1\|2569705_2570320_-	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_011746033.1\|2572752_2573109_-	SUMF1/EgtB/PvdO family nonheme iron enzyme	NA	NA	NA	NA
WP_190271944.1\|2573089_2573245_+	hypothetical protein	NA	NA	NA	NA
WP_011746025.1\|2574161_2575127_-\|transposase	transposase	NA	NA	NA	NA
2574088:2574328	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2619182 : 2711970

Escherichia_phage(25.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011746071.1\|2619182_2620226_-\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
WP_011746072.1\|2620222_2621275_-	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.8e-111	60.7
WP_011746073.1\|2621312_2622302_-	NAD-dependent epimerase/dehydratase family protein	A0A2C9DSV6	Western_grey_kangaroopox_virus	1.7e-13	32.3
WP_049751800.1\|2622512_2623796_+	insulinase family protein	A0A2K9L1M6	Tupanvirus	1.4e-33	25.7
WP_011746075.1\|2623881_2625165_+	trigger factor	NA	NA	NA	NA
WP_011746076.1\|2625276_2626152_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_011746077.1\|2626393_2626771_+	dihydroneopterin aldolase	NA	NA	NA	NA
WP_011746078.1\|2626774_2627332_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_011746080.1\|2629744_2630899_-	ArsA family ATPase	NA	NA	NA	NA
WP_011746081.1\|2630913_2632755_-	hypothetical protein	NA	NA	NA	NA
WP_011746082.1\|2633028_2633274_-	bacteriochlorophyll c-binding family protein	NA	NA	NA	NA
WP_011746083.1\|2633405_2633825_-	chlorosome protein C	NA	NA	NA	NA
WP_011746084.1\|2633955_2635173_-	TRC40/GET3/ArsA family transport-energizing ATPase	NA	NA	NA	NA
WP_041467749.1\|2635443_2636238_+	dihydroorotate dehydrogenase electron transfer subunit	NA	NA	NA	NA
WP_011746086.1\|2636331_2636847_+	single-stranded DNA-binding protein	R9TR60	Vibrio_phage	3.8e-30	54.0
WP_011746087.1\|2636830_2637904_+	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_011746088.1\|2638508_2639504_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_041467750.1\|2639746_2640949_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	V5LQ39	Emiliania_huxleyi_virus	1.4e-38	29.6
WP_190271890.1\|2641423_2641594_+	hypothetical protein	NA	NA	NA	NA
WP_150081139.1\|2641643_2642402_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_011743927.1\|2642485_2644057_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_011746091.1\|2646711_2650515_+	magnesium chelatase subunit H	NA	NA	NA	NA
WP_041467388.1\|2651059_2651266_-	hypothetical protein	NA	NA	NA	NA
WP_011746093.1\|2652103_2655946_+	magnesium chelatase subunit H	NA	NA	NA	NA
WP_011746094.1\|2655991_2656687_+	magnesium protoporphyrin IX methyltransferase	NA	NA	NA	NA
WP_011746095.1\|2656861_2658502_+	magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase	NA	NA	NA	NA
WP_011746096.1\|2658584_2659004_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_041467389.1\|2659037_2659271_-	hypothetical protein	NA	NA	NA	NA
WP_190271891.1\|2659698_2659863_-	hypothetical protein	NA	NA	NA	NA
WP_011746097.1\|2659859_2660156_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_011746098.1\|2661039_2662260_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_011746099.1\|2662325_2670749_-	tandem-95 repeat protein	NA	NA	NA	NA
WP_150081139.1\|2670887_2671646_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_011743927.1\|2671729_2673301_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_011746100.1\|2673867_2674560_-\|transposase	transposase	NA	NA	NA	NA
WP_041467304.1\|2674556_2675099_-\|transposase	transposase	NA	NA	NA	NA
WP_011746102.1\|2676518_2683922_-	hemolysin-type calcium-binding region	NA	NA	NA	NA
WP_041467391.1\|2684335_2688013_-	hypothetical protein	NA	NA	NA	NA
WP_011746105.1\|2687963_2689001_-	hypothetical protein	NA	NA	NA	NA
WP_011746106.1\|2689036_2690359_-	capsular biosynthesis protein	NA	NA	NA	NA
WP_011746107.1\|2690355_2692443_-	capsular polysaccharide biosynthesis protein	NA	NA	NA	NA
WP_011746108.1\|2692765_2694241_-	glycosyltransferase	A0A1V0SAH6	Catovirus	1.2e-12	29.6
WP_150081121.1\|2694330_2695578_-	glycosyltransferase	NA	NA	NA	NA
WP_011746110.1\|2695746_2702148_-	DUF4347 domain-containing protein	NA	NA	NA	NA
WP_011746111.1\|2702661_2709258_-	hemolysin-type calcium-binding region	NA	NA	NA	NA
WP_011746112.1\|2709758_2710244_+\|transposase	transposase	NA	NA	NA	NA
WP_150081122.1\|2710273_2710648_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011745659.1\|2710800_2711970_-\|transposase	IS4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_11

2997533 : 3044536

Leptospira_phage(33.33%)

transposase,integrase

attL 2985995:2986033|attR 3032235:3032273

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2985995:2986033	attL	NA	NA	NA	NA
WP_015961130.1\|2997533_2998586_-\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	6.2e-43	31.6
WP_041467420.1\|2998634_3000008_+\|transposase	IS1380-like element ISCph9 family transposase	NA	NA	NA	NA
WP_041467797.1\|3000482_3001043_-	sugar transferase	NA	NA	NA	NA
WP_015961134.1\|3001080_3002040_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_015961135.1\|3002077_3002926_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_015961136.1\|3002939_3004103_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_041467421.1\|3004132_3004693_-	acyltransferase	NA	NA	NA	NA
WP_015961138.1\|3004934_3005381_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_015961140.1\|3007415_3008711_-	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_150081133.1\|3008856_3010044_-	hypothetical protein	NA	NA	NA	NA
WP_015961142.1\|3010091_3011021_-	hypothetical protein	NA	NA	NA	NA
WP_015961145.1\|3012713_3014195_-	group II intron reverse transcriptase/maturase	NA	NA	NA	NA
WP_015961146.1\|3014773_3016171_-\|transposase	IS1380-like element ISCph9 family transposase	NA	NA	NA	NA
WP_015961147.1\|3016559_3017762_-	glycosyltransferase	NA	NA	NA	NA
WP_015961148.1\|3019435_3020212_-	glycosyltransferase	NA	NA	NA	NA
WP_150081240.1\|3023816_3025853_-	polysaccharide biosynthesis protein	L7Y3T9	Megavirus	3.4e-21	27.5
WP_015961151.1\|3025984_3026383_-	hypothetical protein	NA	NA	NA	NA
WP_015961154.1\|3027459_3027813_-	four helix bundle protein	NA	NA	NA	NA
WP_150081134.1\|3027977_3028205_+	hypothetical protein	NA	NA	NA	NA
WP_015961155.1\|3028373_3028793_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_041467805.1\|3028789_3029038_-	toxin-antitoxin system	NA	NA	NA	NA
WP_015961157.1\|3029301_3029655_-	DUF5615 family PIN-like protein	NA	NA	NA	NA
WP_015961158.1\|3029651_3029882_-	DUF433 domain-containing protein	NA	NA	NA	NA
WP_015961159.1\|3030407_3030653_-	type II toxin-antitoxin system MqsA family antitoxin	NA	NA	NA	NA
WP_015961160.1\|3030649_3030961_-	DUF4258 domain-containing protein	NA	NA	NA	NA
WP_015961161.1\|3031160_3031673_-	ORF6N domain-containing protein	NA	NA	NA	NA
WP_150081135.1\|3031985_3032384_+	hypothetical protein	NA	NA	NA	NA
3032235:3032273	attR	NA	NA	NA	NA
WP_015961162.1\|3032570_3032945_-	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_015961163.1\|3032941_3033169_-	hypothetical protein	NA	NA	NA	NA
WP_150081136.1\|3033323_3033626_+	hypothetical protein	NA	NA	NA	NA
WP_015961164.1\|3033979_3036424_-	polysaccharide biosynthesis tyrosine autokinase	NA	NA	NA	NA
WP_041467810.1\|3036443_3037019_-	SLBB domain-containing protein	NA	NA	NA	NA
WP_150081139.1\|3037890_3038649_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.4e-25	32.4
WP_011743927.1\|3038732_3040304_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_041467426.1\|3041063_3041516_-	putative toxin-antitoxin system toxin component, PIN family	NA	NA	NA	NA
WP_015961169.1\|3041491_3041719_-	AbrB family transcriptional regulator	NA	NA	NA	NA
WP_015961170.1\|3042083_3042905_+	hypothetical protein	NA	NA	NA	NA
WP_011743927.1\|3042964_3044536_+\|transposase	IS21 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_008639

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection