CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_008342	Nitrosomonas eutropha C91 plasmid p2, complete sequence	0 crisprs	cas4	0	0
NC_008341	Nitrosomonas eutropha C91 plasmid p1, complete sequence	0 crisprs	cas4	0	3
NC_008344	Nitrosomonas eutropha C91, complete sequence	2 crisprs	csa3,cas2,cas1,cas4,cas7,cas8c,DinG,cas3,DEDDh,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6,csx16,csx1	5	10

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_008344_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008344_1

2341826-2342637

TypeIII

Consensus_repeat	Method
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	CRISPRCasFinder
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	CRT
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	PILER-CR

11 spacers

cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6,csx16,csx1

The CRISPR arrays of NC_008344_1

>merge|NC_008344|1|2341826-2342637|CRISPRCasFinder,CRT,PILER-CR
GACTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCTATGGAAGATGATATGGGTGAGGAAATCACCTTAGGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCAATGGAAAGGTGTTTGCTCGTCGAAGTCTATCCGGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCGAAATAACCGGATCGACCCCATACAGGCCAGCGACGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCAATGGAAAGGTGTTTGCTCGTCGAAGTCTATCCGGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCGTCTCATCCAAATGCATTAGTGTTTGGATGTGAACGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCAATATCTCTAATGTTGAACACTTCTTTTTTCTTGTGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCGAATATGAGCGCCGGCATCAGAATGGTATTGGGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCTAAATATGAATGTTTGAATGACGCATTTGTAGGTGGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCGATGCGATAAATAACAAAGTAAAGAAACTAGGACTGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCTACGAGATAGGTGAAAAGTACGTCAAATCTCGTGACGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCGCTGCTGCTGTTCTCATATTAGCCCTACATTTAGGTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC

>NC_008344|1|1|2341826-2342637|CRISPRCasFinder
GACTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	TATGGAAGATGATATGGGTGAGGAAATCACCTTAG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	AATGGAAAGGTGTTTGCTCGTCGAAGTCTATCCG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	GAAATAACCGGATCGACCCCATACAGGCCAGCGAC
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	AATGGAAAGGTGTTTGCTCGTCGAAGTCTATCCG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	GTCTCATCCAAATGCATTAGTGTTTGGATGTGAAC
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	AATATCTCTAATGTTGAACACTTCTTTTTTCTTGT
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	GAATATGAGCGCCGGCATCAGAATGGTATTGG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	TAAATATGAATGTTTGAATGACGCATTTGTAGGTG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	GATGCGATAAATAACAAAGTAAAGAAACTAGGACT
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	TACGAGATAGGTGAAAAGTACGTCAAATCTCGTGAC
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	GCTGCTGCTGTTCTCATATTAGCCCTACATTTAG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC

>NC_008344|1|1|2341826-2342637|CRT
GACTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	TATGGAAGATGATATGGGTGAGGAAATCACCTTAG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	AATGGAAAGGTGTTTGCTCGTCGAAGTCTATCCG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	GAAATAACCGGATCGACCCCATACAGGCCAGCGAC
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	AATGGAAAGGTGTTTGCTCGTCGAAGTCTATCCG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	GTCTCATCCAAATGCATTAGTGTTTGGATGTGAAC
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	AATATCTCTAATGTTGAACACTTCTTTTTTCTTGT
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	GAATATGAGCGCCGGCATCAGAATGGTATTGG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	TAAATATGAATGTTTGAATGACGCATTTGTAGGTG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	GATGCGATAAATAACAAAGTAAAGAAACTAGGACT
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	TACGAGATAGGTGAAAAGTACGTCAAATCTCGTGAC
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	GCTGCTGCTGTTCTCATATTAGCCCTACATTTAG
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC

>NC_008344|1|1|2341828-2342637|PILER-CR
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCTA	TGGAAGATGATATGGGTGAGGAAATCACCTTAGGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCAA	TGGAAAGGTGTTTGCTCGTCGAAGTCTATCCGGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCGA	AATAACCGGATCGACCCCATACAGGCCAGCGACGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCAA	TGGAAAGGTGTTTGCTCGTCGAAGTCTATCCGGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCGT	CTCATCCAAATGCATTAGTGTTTGGATGTGAACGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCAA	TATCTCTAATGTTGAACACTTCTTTTTTCTTGTGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCGA	ATATGAGCGCCGGCATCAGAATGGTATTGGGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCTA	AATATGAATGTTTGAATGACGCATTTGTAGGTGGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCGA	TGCGATAAATAACAAAGTAAAGAAACTAGGACTGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCTA	CGAGATAGGTGAAAAGTACGTCAAATCTCGTGACGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTCGC	TGCTGCTGTTCTCATATTAGCCCTACATTTAGGT
CTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008344.1\|WP_011635232.1\|2351896_2353066_+\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09668_csx1_CAS-III	gnl\|CDD\|274040
NC_008344.1\|WP_011635228.1\|2348061_2349030_+\|hypothetical-protein	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	gnl\|CDD\|187794
NC_008344.1\|WP_011635230.1\|2350650_2351607_+\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0091_cas6_CAS-I:CAS-III	gnl\|CDD\|337605
NC_008344.1\|WP_166485023.1\|2338320_2338491_-\|hypothetical-protein	unknown	unknown	unknown
NC_008344.1\|WP_166485000.1\|2335253_2336052_-\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NC_008344.1\|WP_049753127.1\|2331228_2331423_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213264
NC_008344.1\|WP_011635224.1\|2343060_2343993_+\|hypothetical-protein	unknown	unknown	unknown
NC_008344.1\|WP_011635219.1\|2336122_2336668_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|379228
NC_008344.1\|WP_011635217.1\|2332863_2334579_-\|YdiU-family-protein	unknown	unknown	gnl\|CDD\|234583
NC_008344.1\|WP_011635227.1\|2347340_2348057_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_008344.1\|WP_160803437.1\|2344043_2344214_-\|hypothetical-protein	unknown	unknown	unknown
NC_008344.1\|WP_041353579.1\|2344251_2346834_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|274209
NC_008344.1\|WP_041353576.1\|2331841_2332501_-\|pseudouridine-synthase	unknown	unknown	gnl\|CDD\|211334
NC_008344.1\|WP_011635223.1\|2340516_2341686_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340897
NC_008344.1\|WP_011635222.1\|2339312_2340254_+\|delta(1)-pyrroline-2-carboxylate-reductase-family-protein	unknown	unknown	gnl\|CDD\|235996
NC_008344.1\|WP_011635226.1\|2346916_2347288_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|187778
NC_008344.1\|WP_011635231.1\|2351603_2351900_+\|CRISPR-associated-protein-Csx16	csx16	pfam09652_csx16_CAS-I:CAS-III	gnl\|CDD\|200203
NC_008344.1\|WP_166485000.1\|2336664_2337463_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NC_008344.1\|WP_041353861.1\|2337583_2338216_-\|MarC-family-protein	unknown	unknown	gnl\|CDD\|225006
NC_008344.1\|WP_011635229.1\|2349026_2350628_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	mkCas0182_csm5gr7_CAS-III-A	gnl\|CDD\|224251

Protein	Function_ID	Function_description	E-value
NC_008344.1\|WP_011635232.1\|2351896_2353066_+\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	9.28873e-95
NC_008344.1\|WP_011635228.1\|2348061_2349030_+\|hypothetical-protein	gnl\|CDD\|187794	cd09663, Csm4_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.31833e-15
NC_008344.1\|WP_011635219.1\|2336122_2336668_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	9.9001e-09
NC_008344.1\|WP_166485000.1\|2335253_2336052_-\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.81514e-21
NC_008344.1\|WP_049753127.1\|2331228_2331423_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213264	cd03297, ABC_ModC_molybdenum_transporter, ATP-binding cassette domain of the molybdenum transport system. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	2.43827e-17
NC_008344.1\|WP_011635230.1\|2350650_2351607_+\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	4.21772e-08
NC_008344.1\|WP_011635226.1\|2346916_2347288_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|187778	cd09647, Csm2_III-A, CRISPR/Cas system-associated protein Csm2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; signature gene for subtype III-A.	1.70921e-24
NC_008344.1\|WP_011635217.1\|2332863_2334579_-\|YdiU-family-protein	gnl\|CDD\|234583	PRK00029, PRK00029, YdiU family protein.	2.49045e-104
NC_008344.1\|WP_011635227.1\|2347340_2348057_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.40721e-96
NC_008344.1\|WP_041353579.1\|2344251_2346834_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	0
NC_008344.1\|WP_041353576.1\|2331841_2332501_-\|pseudouridine-synthase	gnl\|CDD\|211334	cd02566, PseudoU_synth_RluE, Pseudouridine synthase, Escherichia coli RluE. This group is comprised of bacterial proteins similar to E. coli RluE. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. Escherichia coli RluE makes psi2457 in 23S RNA. psi2457 is not universally conserved.	5.81435e-84
NC_008344.1\|WP_011635223.1\|2340516_2341686_+\|MFS-transporter	gnl\|CDD\|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.59329e-120
NC_008344.1\|WP_011635222.1\|2339312_2340254_+\|delta(1)-pyrroline-2-carboxylate-reductase-family-protein	gnl\|CDD\|235996	PRK07340, PRK07340, delta(1)-pyrroline-2-carboxylate reductase family protein.	5.92524e-154
NC_008344.1\|WP_011635231.1\|2351603_2351900_+\|CRISPR-associated-protein-Csx16	gnl\|CDD\|200203	TIGR02620, hypothetical_protein, putative CRISPR-associated protein, VVA1548 family. This model represents a conserved domain of about 95 amino acids exclusively in species with CRISPR (Clustered Regularly Interspaced Short Palidromic Repeats). In all bacterial species with members so far (Vibrio vulnificus YJ016, Mannheimia succiniciproducens MBEL55E, and Nitrosomonas europaea ATCC 19718) and but not in the archaeon Methanothermobacter thermautotrophicus str. Delta H, the gene for this protein is in the midst of a cluster of Cas protein gene near CRISPR repeats.	4.17636e-52
NC_008344.1\|WP_166485000.1\|2336664_2337463_+\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.81514e-21
NC_008344.1\|WP_041353861.1\|2337583_2338216_-\|MarC-family-protein	gnl\|CDD\|225006	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion].	1.1051e-37
NC_008344.1\|WP_011635229.1\|2349026_2350628_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|224251	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.44469e-14

>NC_008344.1|WP_011635223.1|2340516_2341686_+|MFS-transporter
MLGFGLILIAFNLRPLFASLSVLLPDMLQQQVLTSAQAGYLTTLPVLCLGIFAPLAPWLSQRIGNKRTLLVVMVLLTAGTAMRGWGNILPLFLGSAMAGMAIAIGNVLLPAMVKKEFPQSPALMTGSYTMALCAGAAVAAAGTLPLTQSLETTWATGLALWALPAGIVMLLWLPYAVVPDSAPQNRQLQTVSLWRDSLAWQVTFFMGLQSALGYSIFGWIVPILHDRGLDGVQAGWILSISIVVQLIACFVLPSLAVRCKNQSLINAAMALTAAIGFLGMLFGPIELVWEFGILQGIGQGGLFALALTIIVLRSPDAHIATHLSSMAQSVGYTLAALGPLLIGMLHSLTGGYAASGWLFTALCLGAAISGWGAGRTRLVQACYTSKVRH
>NC_008344.1|WP_011635222.1|2339312_2340254_+|delta(1)-pyrroline-2-carboxylate-reductase-family-protein
MNPPSIVSTFPATEELIVLSRERTAKSLDFSKLVDAIATAALEYDAGQIQSPERMVVPFGIGGVMLSMPATAHDIGIHKLVTVQPANKERQLPTIHGTVTVCDTETGKPICLLDGPEVTGRRTAAVTMLAIRTFLKQAPHEILLIGTGVQARHHVQALYALYPQSKIWVRGRSETASAAFCDQYQSLHGKLVPAEQLISDNVNVVITVTTSTQAVYNETALRDRLVVGVGAFTPEMAELGKVTLNSSAIFVDDLVSARHEAGDLIQADVDWSCVRSLAHALQNQLDESRPRVFKSVGTGAWDLAAARVALQAI
>NC_008344.1|WP_166485023.1|2338320_2338491_-|hypothetical-protein
MMGRLAVDQFYQGIGLARSLLADAVYKVRQLDISVFALAVVAKDDEFDASTGTMAL
>NC_008344.1|WP_041353861.1|2337583_2338216_-|MarC-family-protein
MDQYIQAIVALLAIANPLSAVPVFLQAVDGLDRTQRRKSALLAAISVFTILFVAAVAGNWMLDIFGISISAFRCGGGLVILLMGLTMLQGRTSSVQQESLTHNERRSKIFVPIAMPLVAGPGAITTVITIALAEPYWKNLSVALTAIVVLTMVLWVVLLLSQGVQGLLSPLGQKILLRFFGLILVAIGVQFILAGAYEFFTDAIAQQALR
>NC_008344.1|WP_166485000.1|2336664_2337463_+|IS5-family-transposase
MKRPKYASDISREKFAEIEPLLRSVRRRTKPATVDLYEVFCAVLYLLRTGCQWRYLPDKFPKWQSVYAYWRKWSEPDQDGVSLLEQALKNQVGAAREKLGRNACSTFLIVDAQSVKNTDTAGQKGYDAGKKVSGIKRHIAVDTQGLPHAIAVTTAEVTDRKGALQALKRCKPNLKQIQSLLCDSGYVGQPFAQGVKDILGKHVTVQIARRSELHTFKVIPKRWIVERSFAWLEKNRRLWKNCERKLNTSLQFIHLAFMALILRRS
>NC_008344.1|WP_011635219.1|2336122_2336668_+|GNAT-family-N-acetyltransferase
MTTAAAICAAAMNENPLHIKVFGANPDLRQRRLRRMFPALLAYVKRKGELYGAFIDGNLIGVLGMLPPNTCQPTLRDLIQLLPRMISANSLLGSLRLAIWLGTWARIDPKQPHWHLGPLAIAPQWQYKGVGTQMIEFTINQCAAEEHLYLETDKQSNVDLYQRFGFKSLFTICFSPLIINR
>NC_008344.1|WP_166485000.1|2335253_2336052_-|IS5-family-transposase
MKRPKYASDISREKFAEIEPLLRSVRRRTKPATVDLYEVFCAVLYLLRTGCQWRYLPDKFPKWQSVYAYWRKWSEPDQDGVSLLEQALKNQVGAAREKLGRNACSTFLIVDAQSVKNTDTAGQKGYDAGKKVSGIKRHIAVDTQGLPHAIAVTTAEVTDRKGALQALKRCKPNLKQIQSLLCDSGYVGQPFAQGVKDILGKHVTVQIARRSELHTFKVIPKRWIVERSFAWLEKNRRLWKNCERKLNTSLQFIHLAFMALILRRS
>NC_008344.1|WP_011635217.1|2332863_2334579_-|YdiU-family-protein
MIKRLTQETPPIIATLDDLAKLANYSFMDSLNCDPDAEVNGRNHTPRQVFTGHYVPVNPTPIEDPEYVAHSKNFFRELGFANSMATSADFVRVFSGDLAHVPEPMRKVGWACGYALSIFGTEYYQQCPFQTGNGYGDGRAISVLEAVINGQRWEMQLKGGGRTPYCRGADGRAVLRSSVREFLAQEHMHALGVPTSRSLSLYVSKTEKVRRPWYSEGSHSQDPDMLVSEAVAISTRVASSFIRVGQLELFGRRARKMEHPRAMEELEKIVLHLIDREYDNVIDQKLATTEKVVLLAREFLNRLTSLVANWIRVGYCQGNFNSDNCAAGGFTLDYGPFGFCDVFNPHYQPWTGGGRHYSFLNQPVAAERNFHMFCSALRPLLMAHQDCLAQLDEIQSDFPKVMQAQMEKMWAAKLGLGTFHATLFSELVTLMLQTSVDYTMFFRELSMVPDDIGLLKKSFYKNSTYHADSEGMDKRWSAWLTKWKSLTQSCSREELSRQMKRVNPKYSLREWFVVPAYQQAATGDYSLIQELQEVMTQPYAEQSKDVDEKYYRLKPLELFGVGGSSHLSCSS
>NC_008344.1|WP_041353576.1|2331841_2332501_-|pseudouridine-synthase
MAELILFNKPFHVLSQFTDKRTAAGPERRSTLADWIEIPSVYPAGRLDYDSEGLLLLTDDGFLQHRIASPVQKMPKTYWVQVEGNISASAIAALSAGVMLKDRCTRPAKACAMEEPALWPRVPPVRWRDSIPTSWLELIITEGRNRQVRRMTAAVGFPTLRLIRYRIGSWSLEGLEPGDYRRIRINLPAALPSGNRPAFARPAKLPKRIRKSRRGSRGR
>NC_008344.1|WP_049753127.1|2331228_2331423_-|ATP-binding-cassette-domain-containing-protein
MELKNLADTPPQNINEGQKQRVAVAGALMSNPKILLLNEPLSALDSAMRLKLQDELKWFTKNLA
>NC_008344.1|WP_011635224.1|2343060_2343993_+|hypothetical-protein
MFELAPTCRVNQITEKAAKDMAYVTKSTYTKLSGGWLQPEGRVSIDWIFDFIYEESLASILNQPEAERLYVQKLMLEGKYQSLRIKKQTFSPKYVFSVGMPKFHKTNECHYLTVDFTNYLVPPQISARGAQEVRKFQAFCEQTKKELKGRPDDVFWARVGAKFHIQINPQSVCYENSGVQGVSAMTIAELQQQIRKTVDVSLDMQNGDDGAVIKRVRHAPHIQKALACTADPKRRAIVEQFFTLKRQLINLLFELYRKQMRVVNHVLPIHLLQASGLEPCRKCWGEREAIQRFSLKNADDGLPPIKAEIA
>NC_008344.1|WP_160803437.1|2344043_2344214_-|hypothetical-protein
MYRPLTDKCGGKLAKQDKHAIPDNLHPLTGTGIDDSTLTGRLITRIPAKDGSTSAK
>NC_008344.1|WP_041353579.1|2344251_2346834_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MSLLHSSCRVAFSALLHDLGKFHERTGQPVNGDLAALTTLYKYSHAAHTGGMWDVVEKFAPDLLRGDVSPFSGRTSGVDITDSMANAAAAHHKPGTLLQWIIATADRAASGFERKKFDEYNADAEGETPQHKNRFQARMMSLFEQIRTNPQAPAGQFAYAYPLRALGPEAIFPDKRAAVEPDGDKSAQTEYAALWEQFMQALASIPQSHRNNWPLWLDHFDSAWLAYTQAIPSATNRGVVPDVSLYDHSKAVAALAAALWRWHEETGNTGADALAKLSNPERPDWDEQKLLLIQGDFFGIQNFIFAQGAQTQKHAHKLLRGRSFQVALLAEMAALKLLETLQLPSTSQIINAAGKFLIVAPNTQSAREAVETCRHSFDQWCLQHTYGEIGVGIAQTAASCNDLVSKQFKALTQRLFTELDIAKHRRFDLCDNTAAVREISFTDGPCGYHGRYPADRAAKGEKPASCALSRDQIAIGEALTKHARLLVLNTADSFKNPLDLDYFGYRLVFVNEADASGHHGKLAEQGELVRAWDFDLPEADGSCFHGYARRFVNSYVPIFDNFDQQLSDKYGRWEDEAEFDREHPIKTLHHIACENRRLQENGKWLGEIALVTLKGDIDNLGALFQNGLEEPTFASWAALSRQVNAFFALWLPWYCAHGENGRFRNTYTVFAGGDDFFLIGPWESTLELASAMRKAFTRYVVRDDITFSLGAAMTQPKVPARQLAIAAEAGLHAAKRHDDDAKNAVSLWDVTVNWTEWRTLMEERRDALAQLISEAGNLSTGFIYNLLLLSDQAERDRPETANRRPEDALWRSRLAYRCARLPKHQQATGKALARECGEALKQYRGAYRLPVSVLLYRQRQ
>NC_008344.1|WP_011635226.1|2346916_2347288_+|type-III-A-CRISPR-associated-protein-Csm2
MTLDLKTNPPPATLFSKDAKDIAELLNKDTSKNKSTQIRRFYDELVGWQERIGTDEQKFKDYEAFIHMLNAKAAYAQGRKLVTQEFVEWLNSCIKQVTDTRTLNHFRLHFEAMLGFLKFFKRD
>NC_008344.1|WP_011635227.1|2347340_2348057_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MQLTQIQKIIGTIVLQSGLHIGAGDSEMRIGGTDSPVVKDPLTGQPYIPGSSLKGKIRSLLEWRHGLVLAAGGAPYSFKQLAQDENNSAGRAVIKLFGGAPDKAEDQLVTSIGPTRLAFWDCPLSNDWKIEEVDSRNLLITEVKSENSINRIAGTAESPRFIERVIAGACFDFTLTLKVLAGDDLLDTVLLGLRLLELDSLGGSGSRGYGKIKFAALKLDGTDLMEQFHAIIPFNQTA
>NC_008344.1|WP_011635228.1|2348061_2349030_+|hypothetical-protein
MTPLRVTLRLRSPLGTPLAGDTLFGQLCHAVREMLGEEKLETLLTGYSAGCPWLIVSDGFPSGYLPRPTVPAALQANNEEDPAKRKEAKGKRWIPHDKVHLPLRQLLDIAASDEDVYGKEVCGKQNKPIQAAAFHNTLNRLTGTTGTGEFAPYTQSQIFYQPDQRMDLWCVLDEDRLPCATLLQLLEYIGNVGYGRDASIGLGKFAVEQIEEATLFKQTYPDANAYWTLAPCAPQGQGFDITRSYWQVLTRFGRHGGTLALGANPFKQPLLLAATGAIFTPTGNRAQTRFIGNGLAKVSLMQKTAVHQGYAPVLGICMEESA
>NC_008344.1|WP_011635229.1|2349026_2350628_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MMAPHSYPLKISTLSPVHIGCDEVFEPTNFVINEGLLHVLDPADIAAELDEKEKQQLIQLADSRQPIGSIQHFFKERRARLAQIASQWVDVAPDIAHEYEEKSGKPQQRSGDGRTVYNLFPMARTAFKPLDGAPYLPGSSLKGAIRTAWLNYQNRGKPLLEKQESPTQLQQRLLGYQAGKFENDPFRSVALADARVPDDRMAPPTRIIYAVSKKKKPSERGSSPELKVFLETVRETMVDAFAGELRLTGRIGWQSLCDACNAFYRPQLENELDHEQFRTLFDPQWRTLIKQLLAGELGELMKTRQGFLLRVGKHSGAESLTLEGVRSIKIKTPNGKPDQYRPTTTEKRFASTTRAATSHLLPFGWIWVHACDDAHQYLAAAVQNQVNKYATPILEAHGERIVAADERIANRAKAREEAVRRQAEAAAAEQAKAAAQAAREAALAAMTENQRRVEAFVSRCVRRAEQLRGGKENPNAAIHNEARALVKAAQEGADWTINEKHAVADAIEEWLPKLVKVELKEERKKLKLSALRL
>NC_008344.1|WP_011635230.1|2350650_2351607_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MNTHYLTEPASPVLSLGRYRLDWRVTRSIRLPDYAGSMLRGAFGHALRSIGCITREKDCATCPLRRDCPYTLLFESVPPEHHPLQDFSRIPAPYIIEPPEWGARVLHPGDTLTFHFTLVGRAVEELPIAILAWRRALARGIGSSNGQAELMGIWLERPESSLAIYTPENGSIQKHDTRLACPPLPGDSVRLHLVTPLRLQNNGVPLKAQTITERALLMALVRRLALMSEFHGELAWQPDFHHLGELASSIQGNRQLSWRDWKRYSSRQQQEMALGGVTGRWNLHGKLSAFWPALWFGQWLHAGKNASFGLGHYQICVA
>NC_008344.1|WP_011635231.1|2351603_2351900_+|CRISPR-associated-protein-Csx16
MTIWLVTRHPGAIEWAARQGIQWDKHAAHLDPCEITAGDTVIGSLPINLAAEICNRGARYFNLSLNLPAHLRGQELDAAILTACEARLEEYIVKKANS
>NC_008344.1|WP_011635232.1|2351896_2353066_+|TIGR02221-family-CRISPR-associated-protein
MTTLISFLGKGIADKTTGYRTATYHFDDSSKRTTPYFGLALADYLRPKRLILVGTAGSMWDVFFEQQDASDDDMLDLLIEAVHESRVDAAMLSIQEERLTKNLGLPVICRLISYARDAAEQTKVLLTLAELVHRGEKVFLDVTHGFRHLPMLALVAARYLAHVKDVKVGGLYYGALEMTPTNGETPVLQLDGMLQMLDWVESLATYNKDGDYGVFAPLLQQDGLPEDKAKQLTRAAYFERSSNPVKARETLGSVFSAIKTHNGPMGALFRDALTERINWFSGLDRAAWELALADAYLERRDYVRAVIYLYESLVTRAVLERKFNPNDFSQRNEAWKDAKQGNNQVKNLEYLRNSLAHGIKSDNAKIKNLVIDENRLAAELKKFRHDLFD

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Crispr_ID: NC_008344_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008344_2

2357406-2358142

TypeIII

Consensus_repeat	Method
GTCTCAATCCCTTTGAAATCAGGGCATGGGTGTTTC	PILER-CR
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CRISPRCasFinder
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CRT

10 spacers

cas2,cas1,csx1,csx16,cas6,csm5gr7

The CRISPR arrays of NC_008344_2

>merge|NC_008344|2|2357406-2358142|PILER-CR,CRISPRCasFinder,CRT
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGACAACTAAGAACATTGACACCAGCATCTGACAGGTCGAAACACCCATGCCCTGATTTCAAAGGGATTGAGACCGTATGATGAGTAACCTTCTCCGCCTTCATTTACCGAAACACCCATGCCCTGATTTCAAAGGGATTGAGACCTTCACCTGATTGGGGATTGGCGTACGCGTATGGAAACACCCATGCCCTGATTTCAAAGGGATTGAGACCGTGAGGAAATCTTCCAATTCTTCTTGGTTGCAGGGAAACACCCATGCCCTGATTTCAAAGGGATTGAGACTGATCTCGTGAGCGTGCTTGACGGTGGCGGCAAAGAAACACCCATGCCCTGATTTCAAAGGGATTGAGACGTTTGGATCTTCCGCTTGCGCCCATTTGTACACGGAAACACCCATGCCCTGATTTCAAAGGGATTGAGACGCTGGCCATCCTTGATTTTAAACTTTCCAAACAGAAACACCCATGCCCTGATTTCAAAGGGATTGAGACCGCTGTCTTAAACAGCGTATTAATATAACTACTATAGAAACACCCATGCCCTGATTTCAAAGGGATTGAGACGAACGTTTGTATCATTTGGTATTGGGTCGAGTGAGAAACACCCATGCCCTGATTTCAAAGGGATTGAGACTTGTTTTGAGCCGGGTATATCGTGTACATAATTGAAACACCCATGCCCTGATTTCAAAGGGATTGAGAT

>NC_008344|2|2|2357406-2358142|PILER-CR
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	AACTAAGAACATTGACACCAGCATCTGACAGGTC
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CGTATGATGAGTAACCTTCTCCGCCTTCATTTACC
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CTTCACCTGATTGGGGATTGGCGTACGCGTATG
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CGTGAGGAAATCTTCCAATTCTTCTTGGTTGCAGG
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	TGATCTCGTGAGCGTGCTTGACGGTGGCGGCAAA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	GTTTGGATCTTCCGCTTGCGCCCATTTGTACACG
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	GCTGGCCATCCTTGATTTTAAACTTTCCAAACA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CGCTGTCTTAAACAGCGTATTAATATAACTACTATA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	GAACGTTTGTATCATTTGGTATTGGGTCGAGTGA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	TTGTTTTGAGCCGGGTATATCGTGTACATAATT
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAT

>NC_008344|2|2|2357406-2358142|CRISPRCasFinder
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	AACTAAGAACATTGACACCAGCATCTGACAGGTC
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CGTATGATGAGTAACCTTCTCCGCCTTCATTTACC
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CTTCACCTGATTGGGGATTGGCGTACGCGTATG
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CGTGAGGAAATCTTCCAATTCTTCTTGGTTGCAGG
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	TGATCTCGTGAGCGTGCTTGACGGTGGCGGCAAA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	GTTTGGATCTTCCGCTTGCGCCCATTTGTACACG
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	GCTGGCCATCCTTGATTTTAAACTTTCCAAACA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CGCTGTCTTAAACAGCGTATTAATATAACTACTATA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	GAACGTTTGTATCATTTGGTATTGGGTCGAGTGA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	TTGTTTTGAGCCGGGTATATCGTGTACATAATT
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAT

>NC_008344|2|2|2357406-2358142|CRT
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	AACTAAGAACATTGACACCAGCATCTGACAGGTC
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CGTATGATGAGTAACCTTCTCCGCCTTCATTTACC
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CTTCACCTGATTGGGGATTGGCGTACGCGTATG
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CGTGAGGAAATCTTCCAATTCTTCTTGGTTGCAGG
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	TGATCTCGTGAGCGTGCTTGACGGTGGCGGCAAA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	GTTTGGATCTTCCGCTTGCGCCCATTTGTACACG
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	GCTGGCCATCCTTGATTTTAAACTTTCCAAACA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	CGCTGTCTTAAACAGCGTATTAATATAACTACTATA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	GAACGTTTGTATCATTTGGTATTGGGTCGAGTGA
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAC	TTGTTTTGAGCCGGGTATATCGTGTACATAATT
GAAACACCCATGCCCTGATTTCAAAGGGATTGAGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_008344.1\|WP_011635234.1\|2353562_2354693_+\|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl\|CDD\|274214
NC_008344.1\|WP_011635250.1\|2367920_2368232_+\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|227001
NC_008344.1\|WP_011635230.1\|2350650_2351607_+\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0091_cas6_CAS-I:CAS-III	gnl\|CDD\|337605
NC_008344.1\|WP_041353581.1\|2363166_2364003_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|234599
NC_008344.1\|WP_049753128.1\|2355517_2355859_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_008344.1\|WP_074685601.1\|2355366_2355582_-\|hypothetical-protein	unknown	unknown	unknown
NC_008344.1\|WP_011635238.1\|2355876_2356863_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_008344.1\|WP_011635231.1\|2351603_2351900_+\|CRISPR-associated-protein-Csx16	csx16	pfam09652_csx16_CAS-I:CAS-III	gnl\|CDD\|200203
NC_008344.1\|WP_011635251.1\|2368401_2369370_+\|2-hydroxyacid-dehydrogenase	unknown	unknown	gnl\|CDD\|180588
NC_008344.1\|WP_011635243.1\|2360029_2361166_-\|succinyl-diaminopimelate-desuccinylase	unknown	unknown	gnl\|CDD\|237265
NC_008344.1\|WP_041353864.1\|2358522_2359149_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376887
NC_008344.1\|WP_160803436.1\|2358175_2358316_-\|hypothetical-protein	unknown	unknown	unknown
NC_008344.1\|WP_011635244.1\|2361214_2361997_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224052
NC_008344.1\|WP_011635239.1\|2356871_2357156_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
NC_008344.1\|WP_011635242.1\|2359335_2359806_+\|hypothetical-protein	unknown	unknown	unknown
NC_008344.1\|WP_160803609.1\|2353223_2353370_+\|hypothetical-protein	unknown	unknown	unknown
NC_008344.1\|WP_011635232.1\|2351896_2353066_+\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09668_csx1_CAS-III	gnl\|CDD\|274040
NC_008344.1\|WP_011635247.1\|2364135_2365809_+\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|234861
NC_008344.1\|WP_011635245.1\|2361996_2363142_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376777
NC_008344.1\|WP_011635229.1\|2349026_2350628_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	mkCas0182_csm5gr7_CAS-III-A	gnl\|CDD\|224251

Protein	Function_ID	Function_description	E-value
NC_008344.1\|WP_011635234.1\|2353562_2354693_+\|TIGR02584-family-CRISPR-associated-protein	gnl\|CDD\|274214	TIGR02584, hypothetical_protein_NE0113, CRISPR-associated protein, NE0113 family. Members of this minor CRISPR-associated (Cas) protein family are found in cas gene clusters in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, Mannheimia succiniciproducens MBEL55E, and Verrucomicrobium spinosum.	1.07604e-105
NC_008344.1\|WP_011635250.1\|2367920_2368232_+\|c-type-cytochrome	gnl\|CDD\|227001	COG4654, COG4654, Cytochrome c551/c552 [Energy production and conversion].	1.15176e-24
NC_008344.1\|WP_011635232.1\|2351896_2353066_+\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	9.28873e-95
NC_008344.1\|WP_041353581.1\|2363166_2364003_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|234599	PRK00052, PRK00052, prolipoprotein diacylglyceryl transferase; Reviewed.	1.15774e-122
NC_008344.1\|WP_049753128.1\|2355517_2355859_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.66308e-17
NC_008344.1\|WP_011635238.1\|2355876_2356863_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.33456e-88
NC_008344.1\|WP_011635231.1\|2351603_2351900_+\|CRISPR-associated-protein-Csx16	gnl\|CDD\|200203	TIGR02620, hypothetical_protein, putative CRISPR-associated protein, VVA1548 family. This model represents a conserved domain of about 95 amino acids exclusively in species with CRISPR (Clustered Regularly Interspaced Short Palidromic Repeats). In all bacterial species with members so far (Vibrio vulnificus YJ016, Mannheimia succiniciproducens MBEL55E, and Nitrosomonas europaea ATCC 19718) and but not in the archaeon Methanothermobacter thermautotrophicus str. Delta H, the gene for this protein is in the midst of a cluster of Cas protein gene near CRISPR repeats.	4.17636e-52
NC_008344.1\|WP_011635243.1\|2360029_2361166_-\|succinyl-diaminopimelate-desuccinylase	gnl\|CDD\|237265	PRK13009, PRK13009, succinyl-diaminopimelate desuccinylase; Reviewed.	0
NC_008344.1\|WP_041353864.1\|2358522_2359149_+\|hypothetical-protein	gnl\|CDD\|376887	pfam02663, FmdE, FmdE, Molybdenum formylmethanofuran dehydrogenase operon. This entry represents the FmdE protein that is encode by the molybdenum formylmethanofuran dehydrogenase operon. FmdE does not co-purify with the molybdenum isozyme that is formed by FmdC and FmdB. The domain is typically found as a single copy, but is repeated in some sequence two to three times. It is also common place to find this domain co-occurs with a zinc-beta ribbon domain, suggesting that is may bind nucleic acid and be involved in transcription regulation.	1.60907e-05
NC_008344.1\|WP_011635244.1\|2361214_2361997_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224052	COG1127, Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism].	2.3919e-118
NC_008344.1\|WP_011635239.1\|2356871_2357156_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	6.21238e-14
NC_008344.1\|WP_011635245.1\|2361996_2363142_-\|ABC-transporter-permease	gnl\|CDD\|376777	pfam02405, MlaE, Permease MlaE. MlaE is a permease which in E. coli is a component of the Mla pathway, an ABC transport system that functions to maintain the asymmetry of the outer membrane. In NMB1965 it is involved in L-glutamate import into the cell. In Arabidopsis thaliana TGD1 it is involved in lipid transfer within the cell.	6.00995e-69
NC_008344.1\|WP_011635230.1\|2350650_2351607_+\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	4.21772e-08
NC_008344.1\|WP_011635247.1\|2364135_2365809_+\|dihydroxy-acid-dehydratase	gnl\|CDD\|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
NC_008344.1\|WP_011635251.1\|2368401_2369370_+\|2-hydroxyacid-dehydrogenase	gnl\|CDD\|180588	PRK06487, PRK06487, 2-hydroxyacid dehydrogenase.	0
NC_008344.1\|WP_011635229.1\|2349026_2350628_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|224251	COG1332, COG1332, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.44469e-14

>NC_008344.1|WP_011635239.1|2356871_2357156_+|CRISPR-associated-endonuclease-Cas2
MSDFIICYDITHPRRLARLHRYLVKRAVPLQYSVFLFSGDDRQLEHCMQGAIELIDEKVDDLRVYPLPSRGLKARIGQPALPEGIQWSGLPTAW
>NC_008344.1|WP_011635238.1|2355876_2356863_+|CRISPR-associated-endonuclease-Cas1
MTSLFVDRRGVVLELESGAIVFRENGERIGTVPIAPLTRVFLRGDVKLPAALLGKLGEQGVGVVILSGRIGRPSLLLARPHNDAARRVVQIRLSFDKPFCLQIAKALIERKLTRQIEWFAELRENDMQVRYELSHALRALEEHRSRIGHVSSAASLRGVEGSAAARYFSGLQAVVPDSLHFSGRNRRPPRDPFNALLSLTYTLLHSEIAIALYGTGFDPYVGFYHRLAFGRESLASDLLEPLRPLADQFALALIRKKVLEKDHFSTTEAGCLLGKAGRTRYYAAYGEHSETLRKGINQEIEWLTAQVNEILATAEDDVQPDDSFEDFG
>NC_008344.1|WP_049753128.1|2355517_2355859_+|CRISPR-associated-endonuclease-Cas2
MLPVASLPAYSLRKVNPTMLHMNRSLYLVAYDVCNPRRLYKVCRYLKRYKVGGQKSVFELWVTSAELRTIRADLDELMDAQEDRLHILSLDPRMKPRCYGKASTFTAQYFCIT
>NC_008344.1|WP_074685601.1|2355366_2355582_-|hypothetical-protein
MCSIVGFTLRRLYAGKLATGSIKQTSISNYLCTLFAGWIVIFAMMPHYMRDATDTNSGPDQTSTGRNGSAF
>NC_008344.1|WP_011635234.1|2353562_2354693_+|TIGR02584-family-CRISPR-associated-protein
MSKLLQPHEYPRRILLCVTGLSPQIVTETLYALAVARTPPFIPTEVHLLTTTDGARLARAALLHPDGGHFHALLNDQPQIGHPRFDEDCIHIISHHQKKLADIRTPAENAAAADTITALVAQLTGNADAALHVSIAGGRKTMGFYLGYAFSLFARPQDTLSHILVSSPFEGHPDFFYPPRQPRRLVTRDGHHIDTAEAVVTLAEIPVVRLRHGLPVALITGRAGFSETVATLQQSFAPPRLLIDLEQRHVVCGTTTVTMKPQLLAWLAWWATLARQGQPETTWREADAGLFLDIYRAVVGIDVIDYEKTAELLNNGMEKEFFQTKNAKVERILKDALGSAATPYLLMTAGKRPHTRRGLTLPPESIQISGFDNKQD
>NC_008344.1|WP_160803609.1|2353223_2353370_+|hypothetical-protein
MLDSIIDVLGDVLEKAKDIPPENLAIIGVTFMGIIAILKSSDSERNSL
>NC_008344.1|WP_011635232.1|2351896_2353066_+|TIGR02221-family-CRISPR-associated-protein
MTTLISFLGKGIADKTTGYRTATYHFDDSSKRTTPYFGLALADYLRPKRLILVGTAGSMWDVFFEQQDASDDDMLDLLIEAVHESRVDAAMLSIQEERLTKNLGLPVICRLISYARDAAEQTKVLLTLAELVHRGEKVFLDVTHGFRHLPMLALVAARYLAHVKDVKVGGLYYGALEMTPTNGETPVLQLDGMLQMLDWVESLATYNKDGDYGVFAPLLQQDGLPEDKAKQLTRAAYFERSSNPVKARETLGSVFSAIKTHNGPMGALFRDALTERINWFSGLDRAAWELALADAYLERRDYVRAVIYLYESLVTRAVLERKFNPNDFSQRNEAWKDAKQGNNQVKNLEYLRNSLAHGIKSDNAKIKNLVIDENRLAAELKKFRHDLFD
>NC_008344.1|WP_011635231.1|2351603_2351900_+|CRISPR-associated-protein-Csx16
MTIWLVTRHPGAIEWAARQGIQWDKHAAHLDPCEITAGDTVIGSLPINLAAEICNRGARYFNLSLNLPAHLRGQELDAAILTACEARLEEYIVKKANS
>NC_008344.1|WP_011635230.1|2350650_2351607_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MNTHYLTEPASPVLSLGRYRLDWRVTRSIRLPDYAGSMLRGAFGHALRSIGCITREKDCATCPLRRDCPYTLLFESVPPEHHPLQDFSRIPAPYIIEPPEWGARVLHPGDTLTFHFTLVGRAVEELPIAILAWRRALARGIGSSNGQAELMGIWLERPESSLAIYTPENGSIQKHDTRLACPPLPGDSVRLHLVTPLRLQNNGVPLKAQTITERALLMALVRRLALMSEFHGELAWQPDFHHLGELASSIQGNRQLSWRDWKRYSSRQQQEMALGGVTGRWNLHGKLSAFWPALWFGQWLHAGKNASFGLGHYQICVA
>NC_008344.1|WP_011635229.1|2349026_2350628_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MMAPHSYPLKISTLSPVHIGCDEVFEPTNFVINEGLLHVLDPADIAAELDEKEKQQLIQLADSRQPIGSIQHFFKERRARLAQIASQWVDVAPDIAHEYEEKSGKPQQRSGDGRTVYNLFPMARTAFKPLDGAPYLPGSSLKGAIRTAWLNYQNRGKPLLEKQESPTQLQQRLLGYQAGKFENDPFRSVALADARVPDDRMAPPTRIIYAVSKKKKPSERGSSPELKVFLETVRETMVDAFAGELRLTGRIGWQSLCDACNAFYRPQLENELDHEQFRTLFDPQWRTLIKQLLAGELGELMKTRQGFLLRVGKHSGAESLTLEGVRSIKIKTPNGKPDQYRPTTTEKRFASTTRAATSHLLPFGWIWVHACDDAHQYLAAAVQNQVNKYATPILEAHGERIVAADERIANRAKAREEAVRRQAEAAAAEQAKAAAQAAREAALAAMTENQRRVEAFVSRCVRRAEQLRGGKENPNAAIHNEARALVKAAQEGADWTINEKHAVADAIEEWLPKLVKVELKEERKKLKLSALRL
>NC_008344.1|WP_160803436.1|2358175_2358316_-|hypothetical-protein
MQRKAGSGQADVATQFTALAFAHTQGVKQSSEVVAVVVDHHSLTAS
>NC_008344.1|WP_041353864.1|2358522_2359149_+|hypothetical-protein
MYKERFPDFFADAPAVTLRDPLAQFLGTARDGIMEYRYADAVRLAGHSCPTVAGTWLMTLHGLRALYGNELPVRGEIEVYMADARDAGTTGVVATVVQLVTGAAPETGFHGIGGRFGRNNLLHFDQPLQGEIGLRRKDTGAAVQVVLDASVVPWPNEMRQLLPKAVSGQASSAELQYFGELWQERVRQMLIEHAGDANLVQVNTWVVN
>NC_008344.1|WP_011635242.1|2359335_2359806_+|hypothetical-protein
MDVLSLVAGFLLGVVATYLISAFLLKPGLQKSSDAATGVIITSDTQNLFDQLWQAHEHLLNEMKQDLDNPDFKFHREFYVLKKNWWDWNRWGFHRKGPCLAYFIDDHNDLLPLLDALTSHGLISQIGEADKKSAKFQLSEKLIELLHGKKPTKHAA
>NC_008344.1|WP_011635243.1|2360029_2361166_-|succinyl-diaminopimelate-desuccinylase
MPNSTLTLAQMLIARRSLTPDDDGCQKILVHRLAGLGFNSEAMNFGEVENLWTRKGIDGPLVCFVGHTDVVPTGPVAQWDSDPFTPTVRDGFLYGRGAADMKSSIAAFVTAIEEFVELHPDHKGSIALLITSDEEGPAVEGTVKVVETLQARGEVIDYCIVGEPTCTDRLGDTIKNGRRGSLSGNLTVKGIQGHIAYPHLARNPIHTAAPAIAELAQTVWDDGNEYFPATTWHISNIRGGTGATNVIPGEVNLLFNFRFSTASTVESLKTRVHEILDRHGLEYELVWELSGKPYLTPKGILADALSAAIREVTGVEPELSTSGGTSDGRFIADICSQVVEFGPRNATIHKINESVEVADIERLSRIYRLTLEKLLLQD
>NC_008344.1|WP_011635244.1|2361214_2361997_-|ATP-binding-cassette-domain-containing-protein
MTTAEPVIEIAGLTTRFGQNVIHENINLTVLKGEVLALVGGSGSGKTTLLRQMLGLITPAQGSVKVFGATHYDCGHEKERELRTRSGVLFQQGALFSALTVFDNIALPMRELRILSETMVRDLVMLKLGMVGVEAQHVHKMPSELSGGMIKRVALARALALDPELLFLDEPTAGLDPALSESFVELIRSLREELALTIVMVTHDLDTLVAISDRVVVLANRSIVALGPIPDIIANGRHPFIKDFFGGARGRNALRIFQQL
>NC_008344.1|WP_011635245.1|2361996_2363142_-|ABC-transporter-permease
MPSDLPVDHNPRHQLITTEAGNSCLQLTGSYTLVSLNPSLPAVARELAQLASQPGLYWDLTNIHQLDYAGAVMLWQIWGEQRPDHLLLRPEQEQMFQRLEKVVSLPEPTQRKWFLPVSLLGQQLLRFFDHLAGMISLSGQIVLDIVYLMTHPSRIPVREISANLYRTGAQALGITAIVGFLIGIVLSYLSSEQLHMLGADIYIVNILGMSIIRELGPMLAAILVAGRSGSAMTAQLGVMRVTEELDALTVMGIPHSLRLVLSKIIGLSLALPLIVLWTSSVALLGGLLAADLQVGLSIRYAVTTLPDAVPIANLWLGLGKGVVCGMAIALIACHFGLRIKPNTESLGEGTTNSVVTSITAVIIIDAIFAVAFSSIGIRVAG
>NC_008344.1|WP_041353581.1|2363166_2364003_-|prolipoprotein-diacylglyceryl-transferase
MFVHPQFDPIAISIGPLAVRWYGLMYLLGFFLFIVLGRYRIRHQPGCIFTREMLDDALFFGVLGVVLGGRLGQVLFYEPGYFLQHPLEILAIWHGGMSFHGGFLGVIVAMIWLARKYRLSWLSVTDFIAPLVPLGLGAGRIGNFINGELWGRPTDVPWGMIFPYVDNLPRHPSQLYEFALEGLAFFILMWLYSAKPRPLGAISGMFMIGYGVFRSFCEFFREPDDGFLGVMTLGISMGQWLSLPMIAAGVALVFWAYRHDQKPEKIAQDSRNKRKNRS
>NC_008344.1|WP_011635247.1|2364135_2365809_+|dihydroxy-acid-dehydratase
MPDNRRSQAITKGAKRAPNRAMLRAVGFGDGDFDKPIVGIANGFSTITPCNMGLDTLAKCAEHALKNAGAMPQMFGTITVSDGISMGTEGMKYSLVSREVIADSIETCVQAESMDGVIAIGGCDKNMPGALIALARLNVPSIFVYGGTIKPGHYQGRDLTIVSAFEAVGQHSAHKIDDQELLEVERHACPGAGSCGGMYTANTMSSAIEAMGMSLPHSSTMAAEDEEKRISATRSAEVLVEAIKKQILPRSLITRKSLENAVTVVMAVGGSTNAVLHLLAIAHAAEVDFHIDDFEAIRARVPVLCDLKPSGRYVATDLHRAGGIPQVMKMLLVHGLLHGDCLTISGQTIAEVLKDIPEQPRADQNVIRTWDNPVYEQGHLAILKGNLSPEGAVAKISGVKNPNITGPARVFESEETCMTAILDRKIKPGDVVVIRYEGPRGGPGMREMLSPTSALIGEGLGDSVGLITDGRFSGGTYGMVVGHVAPEAYAGGVIALVEEGDSITIDAHRRLLQLNVSETELERRRAAWQPPAPRYTRGVLAKYAKLVSTASRGAVTD
>NC_008344.1|WP_011635250.1|2367920_2368232_+|c-type-cytochrome
MKTAWLGVFAASALLVAGSVQASPELAAKNNCVACHQVDAKLVGPSFKEIATKYAGKDDETGYLVSKIKGGSTGVWGQIPMPPNVNVSDGDAKALAEWISTLK
>NC_008344.1|WP_011635251.1|2368401_2369370_+|2-hydroxyacid-dehydrogenase
MLTVFLDFGSVTRGDIDRAALEQAVSPWIYHDNTSREQVTERIKGAEIIISNKVQLDRTAIFAADQLKLICVAATGYNNVDLAAAAERNIPVCNVRNYATSSVAQHTLMFMLNFACRFVEYRQLIKKGGWQTSTYFCPLDFGVMELAGKTLGIIGHGELGSAVANIAKAFGMKLLIAEYKSASSIRPGRMAFNDVIQQADFITLHCPLSADTRHLIGKWEFDLMKPSVYLINTARSGLINEDDLLQALYSGRIAGAAIDVLQAEPPVNGNPLLDYPHPNLLITPHSAWASVESRQRMINLLADNIRNFLQNKPFNQINTALQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_008344_1	1.7\|2342286\|32\|NC_008344\|CRISPRCasFinder,CRT	2342286-2342317	32	NZ_CP012644	Rufibacter tibetensis strain 1351 plasmid 1, complete sequence	59065-59096	5	0.844
NC_008344_1	1.18\|2342288\|32\|NC_008344\|PILER-CR	2342288-2342319	32	NZ_CP012644	Rufibacter tibetensis strain 1351 plasmid 1, complete sequence	59065-59096	5	0.844
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP025427	Enterococcus faecium strain SC4 plasmid p2, complete sequence	142623-142657	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP041263	Enterococcus faecium strain VVEswe-R plasmid pVVEswe-R2	3867-3901	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP027511	Enterococcus faecium strain AUSMDU00004055 plasmid unnamed5, complete sequence	90398-90432	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_LR135332	Enterococcus faecium isolate E7471 plasmid 2	3875-3909	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_LR135245	Enterococcus faecium isolate E6988 plasmid 3	4241-4275	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_LR135256	Enterococcus faecium isolate E7098 plasmid 3	4275-4309	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP038997	Enterococcus faecium strain SRR24 plasmid pSRR24	3536-3570	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_LR135490	Enterococcus faecium isolate E8414 plasmid 3	4204-4238	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP044266	Enterococcus faecium strain V1836 plasmid pHVH-V1836-2, complete sequence	129710-129744	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_LR134112	Enterococcus faecium isolate E6043 plasmid 8	4282-4316	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP045014	Enterococcus faecium strain LAC7.2 plasmid pII, complete sequence	4003-4037	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_AP022343	Enterococcus faecium strain KUHS13 plasmid pELF2	97452-97486	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP041272	Enterococcus faecium strain VVEswe-S plasmid pVVEswe-S2	85901-85935	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP019994	Enterococcus faecium isolate 2014-VREF-268 plasmid p268-2	91844-91878	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP035656	Enterococcus faecium strain UAMSEF_09 plasmid unnamed2	4132-4166	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP035662	Enterococcus faecium strain UAMSEF_20 plasmid unnamed2	77110-77144	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP019971	Enterococcus faecium isolate 2014-VREF-114 plasmid p114-1 sequence	24705-24739	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP040238	Enterococcus faecium strain VB3025 plasmid unnamed2, complete sequence	14709-14743	8	0.771
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_MG640601	Enterococcus faecium strain SRR6 plasmid pEMSRR6, complete sequence	2182-2216	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP025427	Enterococcus faecium strain SC4 plasmid p2, complete sequence	142623-142657	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP041263	Enterococcus faecium strain VVEswe-R plasmid pVVEswe-R2	3867-3901	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP027511	Enterococcus faecium strain AUSMDU00004055 plasmid unnamed5, complete sequence	90398-90432	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_LR135332	Enterococcus faecium isolate E7471 plasmid 2	3875-3909	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_LR135245	Enterococcus faecium isolate E6988 plasmid 3	4241-4275	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_LR135256	Enterococcus faecium isolate E7098 plasmid 3	4275-4309	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP038997	Enterococcus faecium strain SRR24 plasmid pSRR24	3536-3570	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_LR135490	Enterococcus faecium isolate E8414 plasmid 3	4204-4238	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP044266	Enterococcus faecium strain V1836 plasmid pHVH-V1836-2, complete sequence	129710-129744	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_LR134112	Enterococcus faecium isolate E6043 plasmid 8	4282-4316	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP045014	Enterococcus faecium strain LAC7.2 plasmid pII, complete sequence	4003-4037	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_AP022343	Enterococcus faecium strain KUHS13 plasmid pELF2	97452-97486	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP041272	Enterococcus faecium strain VVEswe-S plasmid pVVEswe-S2	85901-85935	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP019994	Enterococcus faecium isolate 2014-VREF-268 plasmid p268-2	91844-91878	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP035656	Enterococcus faecium strain UAMSEF_09 plasmid unnamed2	4132-4166	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP035662	Enterococcus faecium strain UAMSEF_20 plasmid unnamed2	77110-77144	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP019971	Enterococcus faecium isolate 2014-VREF-114 plasmid p114-1 sequence	24705-24739	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP040238	Enterococcus faecium strain VB3025 plasmid unnamed2, complete sequence	14709-14743	8	0.771
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_MG640601	Enterococcus faecium strain SRR6 plasmid pEMSRR6, complete sequence	2182-2216	8	0.771
NC_008344_2	2.1\|2357442\|34\|NC_008344\|PILER-CR,CRISPRCasFinder,CRT	2357442-2357475	34	NZ_AP017566	Pseudanabaena sp. ABRG5-3 plasmid ABRG53f, complete sequence	14514-14547	8	0.765
NC_008344_1	1.6\|2342215\|35\|NC_008344\|CRISPRCasFinder,CRT	2342215-2342249	35	NZ_CP041196	Weissella cibaria strain CBA3612 plasmid pCBA3612-03, complete sequence	15373-15407	10	0.714
NC_008344_1	1.17\|2342217\|35\|NC_008344\|PILER-CR	2342217-2342251	35	NZ_CP041196	Weissella cibaria strain CBA3612 plasmid pCBA3612-03, complete sequence	15373-15407	10	0.714
NC_008344_2	2.1\|2357442\|34\|NC_008344\|PILER-CR,CRISPRCasFinder,CRT	2357442-2357475	34	MN694574	Marine virus AFVG_250M706, complete genome	6782-6815	10	0.706

1. spacer 1.7|2342286|32|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP012644 (Rufibacter tibetensis strain 1351 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.844

gaatatgagcgccggcatcagaatggtattgg--	CRISPR spacer
gaatatgagcgctggcatcaggatg--tttggcc	Protospacer
************.********.***   ****

2. spacer 1.18|2342288|32|NC_008344|PILER-CR matches to NZ_CP012644 (Rufibacter tibetensis strain 1351 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.844

gaatatgagcgccggcatcagaatggtattgg--	CRISPR spacer
gaatatgagcgctggcatcaggatg--tttggcc	Protospacer
************.********.***   ****

3. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP025427 (Enterococcus faecium strain SC4 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

4. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP041263 (Enterococcus faecium strain VVEswe-R plasmid pVVEswe-R2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

5. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP027511 (Enterococcus faecium strain AUSMDU00004055 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

6. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_LR135332 (Enterococcus faecium isolate E7471 plasmid 2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

7. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_LR135245 (Enterococcus faecium isolate E6988 plasmid 3) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

8. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_LR135256 (Enterococcus faecium isolate E7098 plasmid 3) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

9. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP038997 (Enterococcus faecium strain SRR24 plasmid pSRR24) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

10. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_LR135490 (Enterococcus faecium isolate E8414 plasmid 3) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

11. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP044266 (Enterococcus faecium strain V1836 plasmid pHVH-V1836-2, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

12. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_LR134112 (Enterococcus faecium isolate E6043 plasmid 8) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

13. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP045014 (Enterococcus faecium strain LAC7.2 plasmid pII, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

14. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_AP022343 (Enterococcus faecium strain KUHS13 plasmid pELF2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

15. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP041272 (Enterococcus faecium strain VVEswe-S plasmid pVVEswe-S2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

16. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP019994 (Enterococcus faecium isolate 2014-VREF-268 plasmid p268-2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

17. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP035656 (Enterococcus faecium strain UAMSEF_09 plasmid unnamed2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

18. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP035662 (Enterococcus faecium strain UAMSEF_20 plasmid unnamed2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

19. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP019971 (Enterococcus faecium isolate 2014-VREF-114 plasmid p114-1 sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

20. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP040238 (Enterococcus faecium strain VB3025 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

21. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_MG640601 (Enterococcus faecium strain SRR6 plasmid pEMSRR6, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

22. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP025427 (Enterococcus faecium strain SC4 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

23. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP041263 (Enterococcus faecium strain VVEswe-R plasmid pVVEswe-R2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

24. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP027511 (Enterococcus faecium strain AUSMDU00004055 plasmid unnamed5, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

25. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_LR135332 (Enterococcus faecium isolate E7471 plasmid 2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

26. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_LR135245 (Enterococcus faecium isolate E6988 plasmid 3) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

27. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_LR135256 (Enterococcus faecium isolate E7098 plasmid 3) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

28. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP038997 (Enterococcus faecium strain SRR24 plasmid pSRR24) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

29. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_LR135490 (Enterococcus faecium isolate E8414 plasmid 3) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

30. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP044266 (Enterococcus faecium strain V1836 plasmid pHVH-V1836-2, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

31. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_LR134112 (Enterococcus faecium isolate E6043 plasmid 8) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

32. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP045014 (Enterococcus faecium strain LAC7.2 plasmid pII, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

33. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_AP022343 (Enterococcus faecium strain KUHS13 plasmid pELF2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

34. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP041272 (Enterococcus faecium strain VVEswe-S plasmid pVVEswe-S2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

35. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP019994 (Enterococcus faecium isolate 2014-VREF-268 plasmid p268-2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

36. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP035656 (Enterococcus faecium strain UAMSEF_09 plasmid unnamed2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

37. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP035662 (Enterococcus faecium strain UAMSEF_20 plasmid unnamed2) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

38. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP019971 (Enterococcus faecium isolate 2014-VREF-114 plasmid p114-1 sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

39. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP040238 (Enterococcus faecium strain VB3025 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

40. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_MG640601 (Enterococcus faecium strain SRR6 plasmid pEMSRR6, complete sequence) position: , mismatch: 8, identity: 0.771

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
tctatctctcatgttgaacgcttctttctgttttt	Protospacer
  ******* *********.*******.* .** *

41. spacer 2.1|2357442|34|NC_008344|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP017566 (Pseudanabaena sp. ABRG5-3 plasmid ABRG53f, complete sequence) position: , mismatch: 8, identity: 0.765

aactaag--aacattgacaccagcatctgacaggtc	CRISPR spacer
--tcaagacaatattgacaccagcatctgaaagctt	Protospacer
  ..***  **.****************** ** *.

42. spacer 1.6|2342215|35|NC_008344|CRISPRCasFinder,CRT matches to NZ_CP041196 (Weissella cibaria strain CBA3612 plasmid pCBA3612-03, complete sequence) position: , mismatch: 10, identity: 0.714

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
aataactctaatgttgaacactcctgcattaagag	Protospacer
**** *****************.** . **   .

43. spacer 1.17|2342217|35|NC_008344|PILER-CR matches to NZ_CP041196 (Weissella cibaria strain CBA3612 plasmid pCBA3612-03, complete sequence) position: , mismatch: 10, identity: 0.714

aatatctctaatgttgaacacttcttttttcttgt	CRISPR spacer
aataactctaatgttgaacactcctgcattaagag	Protospacer
**** *****************.** . **   .

44. spacer 2.1|2357442|34|NC_008344|PILER-CR,CRISPRCasFinder,CRT matches to MN694574 (Marine virus AFVG_250M706, complete genome) position: , mismatch: 10, identity: 0.706

aactaagaacattgacaccagcatctgacaggtc	CRISPR spacer
tcctaagaacattgcctccagcatctgttcttcc	Protospacer
  ************ * ********** .   .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

129381 : 138122

Acinetobacter_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041353396.1\|129381_131145_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	2.4e-63	28.9
WP_011633265.1\|131336_131933_-	cytochrome P460 family protein	NA	NA	NA	NA
WP_011633266.1\|132020_132941_-	indole-3-glycerol-phosphate synthase	A0A0P0IR83	Acinetobacter_phage	3.1e-54	44.1
WP_011633267.1\|132951_133977_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	5.4e-84	49.6
WP_011633268.1\|133973_134576_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.8e-72	63.2
WP_011633269.1\|134702_136202_+	HAMP domain-containing histidine kinase	Q6XLV6	Feldmannia_irregularis_virus	3.8e-09	29.6
WP_011633270.1\|136198_136738_+	hypothetical protein	NA	NA	NA	NA
WP_011633271.1\|136754_138122_+	sigma 54-interacting transcriptional regulator	W8CYM9	Bacillus_phage	1.5e-09	35.7

DBSCAN-SWA_2

1069969 : 1103807

Enterobacteria_phage(33.33%)

integrase,transposase

attL 1101659:1101718|attR 1108694:1108858

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011634114.1\|1069969_1071952_-\|integrase	integrase	NA	NA	NA	NA
WP_011634115.1\|1072174_1074976_-	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_011634116.1\|1075099_1076026_+	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_110332584.1\|1076042_1076828_+	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_011634118.1\|1076842_1077871_+	uroporphyrinogen-III C-methyltransferase	NA	NA	NA	NA
WP_011634119.1\|1077867_1079049_+	heme biosynthesis protein HemY	NA	NA	NA	NA
WP_011634120.1\|1079055_1080102_-	CDP-6-deoxy-delta-3,4-glucoseen reductase	NA	NA	NA	NA
WP_011634121.1\|1080133_1081039_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_011634122.1\|1081098_1082319_+	type II secretion system F family protein	NA	NA	NA	NA
WP_011634123.1\|1082362_1083223_+	prepilin peptidase	NA	NA	NA	NA
WP_011634124.1\|1083226_1083838_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_011634125.1\|1083910_1084666_+	cell division protein ZapD	NA	NA	NA	NA
WP_011634126.1\|1084682_1084877_+	DNA gyrase inhibitor YacG	NA	NA	NA	NA
WP_011634127.1\|1084944_1086279_-	amino-acid N-acetyltransferase	NA	NA	NA	NA
WP_011634128.1\|1086302_1087064_-	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_011634129.1\|1087161_1087719_+	thioredoxin family protein	NA	NA	NA	NA
WP_011634130.1\|1087721_1088525_+	inositol monophosphatase family protein	NA	NA	NA	NA
WP_011634131.1\|1088618_1090205_-	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_041353727.1\|1090522_1092187_+	alginate export family protein	NA	NA	NA	NA
WP_011634133.1\|1092232_1092568_+	hypothetical protein	NA	NA	NA	NA
WP_107818442.1\|1095542_1096406_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011634137.1\|1096409_1097369_-	class A beta-lactamase	Q1MVP3	Enterobacteria_phage	4.6e-45	40.8
WP_011634138.1\|1097365_1097980_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011634139.1\|1098089_1098581_-	hypothetical protein	NA	NA	NA	NA
WP_143055271.1\|1098716_1099067_-	hypothetical protein	NA	NA	NA	NA
WP_011634140.1\|1099144_1099585_-	hypothetical protein	NA	NA	NA	NA
WP_110332632.1\|1099590_1100079_-	tryptophan-rich sensory protein	NA	NA	NA	NA
WP_011634142.1\|1100130_1100280_-\|transposase	transposase	NA	NA	NA	NA
WP_166484991.1\|1100456_1101627_+\|transposase	IS3-like element ISNieu3 family transposase	A0A0P0I4A4	Acinetobacter_phage	2.1e-60	45.1
1101659:1101718	attL	NA	NA	NA	NA
WP_011634143.1\|1101824_1102190_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	U5P429	Shigella_phage	5.0e-24	54.7
WP_049753094.1\|1102255_1103218_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_082211247.1\|1103174_1103807_-\|transposase	transposase	NA	NA	NA	NA
1108694:1108858	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1107624 : 1165593

Acinetobacter_phage(11.11%)

protease,integrase,transposase

attL 1160113:1160137|attR 1165637:1165661

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082211248.1\|1107624_1108587_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	1.5e-35	38.7
WP_160803634.1\|1108877_1109012_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_011634151.1\|1109326_1112512_-	AAA family ATPase	NA	NA	NA	NA
WP_166484994.1\|1112513_1113572_-	hypothetical protein	NA	NA	NA	NA
WP_049753095.1\|1113501_1114614_-	DUF559 domain-containing protein	NA	NA	NA	NA
WP_011634154.1\|1115032_1117417_-	sucrose synthase	NA	NA	NA	NA
WP_011634155.1\|1117427_1119566_-	HAD-IIB family hydrolase	NA	NA	NA	NA
WP_011634156.1\|1119576_1120506_-	carbohydrate kinase	NA	NA	NA	NA
WP_011634157.1\|1120701_1122801_-	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_011634158.1\|1122879_1124073_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_011634159.1\|1124458_1124731_-	response regulator transcription factor	NA	NA	NA	NA
WP_041353466.1\|1125191_1126547_+	hypothetical protein	NA	NA	NA	NA
WP_107818412.1\|1126666_1127047_+	hypothetical protein	NA	NA	NA	NA
WP_011634162.1\|1127185_1127878_+	C39 family peptidase	NA	NA	NA	NA
WP_107818415.1\|1127926_1128403_+	hypothetical protein	NA	NA	NA	NA
WP_041353467.1\|1128426_1129809_+	hypothetical protein	NA	NA	NA	NA
WP_011634165.1\|1129863_1130394_-	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_049753154.1\|1130606_1131698_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.3e-53	34.6
WP_011634167.1\|1131803_1133024_+	glycosyltransferase, exosortase A system-associated	A0A1V0SL50	Klosneuvirus	4.5e-29	23.9
WP_011634168.1\|1133124_1134447_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.2e-77	37.8
WP_011634169.1\|1134582_1134765_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_166484995.1\|1134934_1135078_+	hypothetical protein	NA	NA	NA	NA
WP_041353468.1\|1135274_1135529_+	hypothetical protein	NA	NA	NA	NA
WP_011634171.1\|1135633_1136911_+	glycosyltransferase	NA	NA	NA	NA
WP_011634172.1\|1136922_1138278_+	phenylacetate--CoA ligase family protein	NA	NA	NA	NA
WP_011634173.1\|1138279_1138900_-	exopolysaccharide biosynthesis protein	NA	NA	NA	NA
WP_011634174.1\|1139178_1139658_+	hypothetical protein	NA	NA	NA	NA
WP_011634175.1\|1139747_1140905_+	hypothetical protein	NA	NA	NA	NA
WP_011634176.1\|1140956_1141772_+	NTP transferase domain-containing protein	NA	NA	NA	NA
WP_011634177.1\|1141790_1142864_+	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_011634178.1\|1142863_1143922_+	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_011634179.1\|1143938_1145156_+	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_107818413.1\|1145157_1146141_+	kinase	NA	NA	NA	NA
WP_011634181.1\|1146154_1147123_+	hypothetical protein	NA	NA	NA	NA
WP_011634182.1\|1147183_1147831_+	DUF2959 domain-containing protein	NA	NA	NA	NA
WP_110332597.1\|1147841_1148297_-	DUF721 domain-containing protein	NA	NA	NA	NA
WP_011634184.1\|1148789_1151519_+	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_011634185.1\|1151698_1152304_+	ubiquinol-cytochrome c reductase iron-sulfur subunit	NA	NA	NA	NA
WP_011634186.1\|1152305_1153553_+	cytochrome bc complex cytochrome b subunit	NA	NA	NA	NA
WP_011634187.1\|1153549_1154254_+	cytochrome c1	NA	NA	NA	NA
WP_011634188.1\|1154305_1154905_+	glutathione S-transferase N-terminal domain-containing protein	NA	NA	NA	NA
WP_011634189.1\|1154901_1155330_+\|protease	ClpXP protease specificity-enhancing factor	NA	NA	NA	NA
WP_082211250.1\|1155524_1155680_-\|integrase	tyrosine-type recombinase/integrase	A0A088CD23	Shigella_phage	1.2e-14	72.0
WP_011634191.1\|1155765_1156224_-\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	6.5e-05	28.3
WP_011634192.1\|1156365_1156791_-	RNA polymerase-binding protein DksA	NA	NA	NA	NA
WP_107818414.1\|1157152_1158868_-	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	6.0e-19	29.9
WP_041353469.1\|1158830_1159682_-	HDOD domain-containing protein	NA	NA	NA	NA
1160113:1160137	attL	NA	NA	NA	NA
WP_041353470.1\|1160634_1160850_-	hypothetical protein	NA	NA	NA	NA
WP_011634196.1\|1161241_1162792_-	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_011634197.1\|1162788_1163247_-	toprim domain-containing protein	A0A2I7RAI5	Vibrio_phage	7.9e-11	34.0
WP_011634198.1\|1163281_1163785_-	PriCT-2 domain-containing protein	NA	NA	NA	NA
WP_011634199.1\|1163866_1164103_-	hypothetical protein	NA	NA	NA	NA
WP_011634200.1\|1164411_1165593_-\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	4.3e-85	39.7
1165637:1165661	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1374504 : 1439458

Acinetobacter_phage(11.11%)

integrase,transposase

attL 1375997:1376011|attR 1438496:1438510

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001138073.1\|1374504_1377477_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.1
1375997:1376011	attL	NA	NA	NA	NA
WP_011634374.1\|1377612_1378872_-	putative Na+/H+ antiporter	NA	NA	NA	NA
WP_110332638.1\|1378929_1380034_-	peptide chain release factor 2	G0YKC3	Acinetobacter_phage	4.1e-05	44.6
WP_011634376.1\|1380151_1381999_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_011634377.1\|1382016_1383264_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	3.1e-94	46.2
WP_011634378.1\|1383416_1383893_+	DUF421 domain-containing protein	NA	NA	NA	NA
WP_011634379.1\|1384411_1384867_-	DUF4112 domain-containing protein	NA	NA	NA	NA
WP_166484997.1\|1384993_1386165_-\|transposase	IS3-like element ISNieu3 family transposase	A0A0P0I4A4	Acinetobacter_phage	8.1e-60	44.7
WP_011634382.1\|1386597_1386744_+\|transposase	transposase	NA	NA	NA	NA
WP_011634385.1\|1389485_1389824_-	stress-induced protein	NA	NA	NA	NA
WP_011634386.1\|1390964_1392056_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-32	36.1
WP_011634387.1\|1392052_1392955_+	ABC transporter permease	NA	NA	NA	NA
WP_011634388.1\|1392974_1393760_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_041353757.1\|1393777_1394866_+	spermidine/putrescine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011634390.1\|1394870_1395179_+	NAD(P)H-dependent oxidoreductase subunit E	NA	NA	NA	NA
WP_011634391.1\|1395498_1396302_+	hypothetical protein	NA	NA	NA	NA
WP_011634392.1\|1396303_1397752_+	Eco57I restriction-modification methylase domain-containing protein	A0A1V0SF91	Hokovirus	6.6e-35	29.9
WP_011634393.1\|1397755_1400218_+	DEAD/DEAH box helicase family protein	NA	NA	NA	NA
WP_011634394.1\|1400279_1404041_-	ATP-dependent RNA helicase HrpA	A0A1V0SBU4	Catovirus	1.2e-51	28.0
WP_011634395.1\|1404047_1404527_-	hotdog fold thioesterase	NA	NA	NA	NA
WP_011634396.1\|1404557_1405667_-	3-deoxy-7-phosphoheptulonate synthase	A0A2I6UFP9	Klebsiella_phage	4.8e-78	47.4
WP_011634397.1\|1405811_1407467_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	8.9e-12	28.7
WP_011634398.1\|1407614_1408193_+	DUF2062 domain-containing protein	NA	NA	NA	NA
WP_011634399.1\|1408205_1409360_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_011634400.1\|1409356_1410028_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.9e-31	37.5
WP_011634401.1\|1410024_1411227_+	ABC transporter permease	NA	NA	NA	NA
WP_011634402.1\|1411232_1412432_+	ABC transporter permease	NA	NA	NA	NA
WP_041353488.1\|1412441_1412966_-	cytochrome P460 family protein	NA	NA	NA	NA
WP_041353489.1\|1413564_1414407_+	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	1.7e-19	35.8
WP_011634405.1\|1414409_1415123_+	2OG-Fe(II) oxygenase	NA	NA	NA	NA
WP_041353490.1\|1415308_1415557_+	metal-binding protein	NA	NA	NA	NA
WP_011634406.1\|1415532_1416159_+	alpha-ketoglutarate-dependent dioxygenase AlkB	A0A1X6WG33	Pacmanvirus	2.3e-16	37.7
WP_041353491.1\|1416288_1416879_-	DUF938 domain-containing protein	NA	NA	NA	NA
WP_011634408.1\|1416896_1417277_-	glutathione S-transferase N-terminal domain-containing protein	NA	NA	NA	NA
WP_011634410.1\|1418333_1418942_-	glutathione transferase GstA	NA	NA	NA	NA
WP_049753158.1\|1419916_1423447_+	exodeoxyribonuclease V subunit gamma	NA	NA	NA	NA
WP_011634412.1\|1423462_1427149_+	exodeoxyribonuclease V subunit beta	A7KV33	Bacillus_phage	1.1e-09	21.5
WP_011634413.1\|1427145_1429188_+	exodeoxyribonuclease V subunit alpha	A0A1P8DII4	Virus_Rctr197k	3.8e-20	25.1
WP_011634414.1\|1429206_1430511_-	M18 family aminopeptidase	NA	NA	NA	NA
WP_011634415.1\|1430533_1430962_-	PIN domain-containing protein	NA	NA	NA	NA
WP_041353760.1\|1430961_1431207_-	hypothetical protein	NA	NA	NA	NA
WP_011634417.1\|1431291_1432629_-	GHKL domain-containing protein	W8CYF6	Bacillus_phage	2.0e-09	21.3
WP_011634418.1\|1432625_1433312_-	response regulator transcription factor	NA	NA	NA	NA
WP_011634419.1\|1433380_1433671_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_041353492.1\|1433756_1434116_-	DUF3824 domain-containing protein	NA	NA	NA	NA
WP_041353761.1\|1434413_1434959_+	DUF924 domain-containing protein	NA	NA	NA	NA
WP_011634422.1\|1435094_1436084_-\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	6.8e-68	45.5
WP_011634423.1\|1436209_1437010_+	DUF4145 domain-containing protein	M1PSB6	Streptococcus_phage	2.9e-32	40.6
WP_011634424.1\|1437086_1437584_+	hypothetical protein	NA	NA	NA	NA
WP_011634425.1\|1437607_1438108_+	hypothetical protein	NA	NA	NA	NA
WP_166484998.1\|1438230_1439458_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	2.6e-125	78.1
1438496:1438510	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1500514 : 1595675

105

Pseudomonas_phage(16.67%)

tail,protease,terminase,tRNA,transposase,integrase,head,holin,capsid,portal

attL 1532788:1532832|attR 1569828:1569872

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_166485000.1\|1500514_1501313_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_110332563.1\|1501381_1501633_+	hypothetical protein	NA	NA	NA	NA
WP_166485029.1\|1501730_1502852_+	hypothetical protein	NA	NA	NA	NA
WP_011634477.1\|1502851_1505806_+	EAL domain-containing protein	NA	NA	NA	NA
WP_160803492.1\|1505876_1506047_-	hypothetical protein	NA	NA	NA	NA
WP_011634478.1\|1506284_1506701_-	OsmC family protein	NA	NA	NA	NA
WP_011634479.1\|1506701_1507775_-	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_011634480.1\|1507789_1508284_-	hypothetical protein	NA	NA	NA	NA
WP_011634481.1\|1508303_1510910_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	2.2e-182	40.8
WP_011634482.1\|1511064_1512105_+\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_011634483.1\|1512101_1513187_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.5e-87	48.5
WP_011634484.1\|1513251_1513716_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	3.0e-10	44.4
WP_011634485.1\|1513802_1515650_+	protein translocase subunit SecD	NA	NA	NA	NA
WP_011634486.1\|1515674_1516607_+	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	2.6e-45	38.9
WP_011634487.1\|1516646_1517024_+	DUF971 domain-containing protein	NA	NA	NA	NA
WP_110332562.1\|1517073_1517808_+	bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE	NA	NA	NA	NA
WP_011634489.1\|1517860_1518829_-	agmatinase	NA	NA	NA	NA
WP_011634490.1\|1518992_1519475_-	lipoprotein signal peptidase	NA	NA	NA	NA
WP_011634491.1\|1519516_1522324_-\|tRNA	isoleucine--tRNA ligase	K7YVP8	Megavirus	3.3e-75	26.0
WP_011634492.1\|1522325_1523303_-	bifunctional riboflavin kinase/FAD synthetase	A0A1V0SD03	Indivirus	9.6e-06	32.6
WP_011634493.1\|1523414_1523846_-	group III truncated hemoglobin	NA	NA	NA	NA
WP_082211280.1\|1523977_1526257_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011634495.1\|1526266_1527244_+	ABC transporter permease	NA	NA	NA	NA
WP_011634496.1\|1527375_1529031_+	diguanylate cyclase	NA	NA	NA	NA
WP_011634497.1\|1529079_1530024_+	DnaJ domain-containing protein	A0A2L0UZR4	Agrobacterium_phage	8.4e-23	29.1
WP_041353774.1\|1530035_1530332_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_011634499.1\|1530419_1531283_+	DUF2914 domain-containing protein	NA	NA	NA	NA
WP_011634500.1\|1531299_1531839_+	NUDIX hydrolase	NA	NA	NA	NA
1532788:1532832	attL	NA	NA	NA	NA
WP_011634501.1\|1533356_1533842_-	hypothetical protein	NA	NA	NA	NA
WP_011634502.1\|1533831_1534089_-	hypothetical protein	NA	NA	NA	NA
WP_011634503.1\|1534091_1534583_-	hypothetical protein	I6NSS1	Burkholderia_phage	2.6e-36	51.6
WP_011634504.1\|1534582_1534903_-	hypothetical protein	NA	NA	NA	NA
WP_110332561.1\|1534899_1535226_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_011634506.1\|1535484_1536420_-	hypothetical protein	NA	NA	NA	NA
WP_166485001.1\|1536429_1538910_-	hypothetical protein	A0A0S0N6L2	Pseudomonas_phage	6.6e-168	39.4
WP_041353775.1\|1539199_1539382_-	hypothetical protein	L7P837	Pseudomonas_phage	5.9e-10	58.8
WP_011634509.1\|1539399_1539627_-	hypothetical protein	A0A2D0W9G1	Bordetella_phage	7.6e-23	69.7
WP_041353501.1\|1539634_1540405_-	phage BR0599 family protein	A0A0K1LLK5	Rhodobacter_phage	5.3e-68	50.8
WP_011634511.1\|1540401_1541571_-	hypothetical protein	A0A0K1LM02	Rhodobacter_phage	4.5e-18	33.7
WP_166485002.1\|1541563_1543936_-\|tail	phage tail length tape measure family protein	A0A172PZU6	Pseudomonas_phage	7.7e-17	34.9
WP_041353502.1\|1543935_1544211_-	hypothetical protein	A0A1J0GUY0	Halomonas_phage	2.7e-22	50.0
WP_011634514.1\|1544222_1544573_-\|tail	phage tail assembly chaperone family protein, TAC	Q9MCA4	Pseudomonas_phage	2.3e-34	62.9
WP_011634515.1\|1544581_1545298_-\|tail	tail protein	A0A286S1Q8	Klebsiella_phage	3.0e-41	40.3
WP_011634516.1\|1545303_1545666_-	DUF3168 domain-containing protein	A0A1J0GUW9	Halomonas_phage	8.4e-32	54.2
WP_011634517.1\|1545662_1546196_-	phage protein	A0A1J0GUY2	Halomonas_phage	6.4e-28	42.1
WP_011634518.1\|1546195_1546531_-\|head	phage head closure protein	A0A1J0GUY4	Halomonas_phage	4.6e-16	46.6
WP_011634519.1\|1546532_1547090_-	hypothetical protein	H9YSG3	environmental_Halophage	5.8e-08	27.4
WP_011634520.1\|1547146_1547446_-	hypothetical protein	NA	NA	NA	NA
WP_011634521.1\|1547455_1548682_-\|capsid	phage major capsid protein	C7BGH0	Burkholderia_phage	9.4e-75	40.8
WP_110332564.1\|1548763_1549486_-\|protease	Clp protease ClpP	C7BGG9	Burkholderia_phage	9.1e-62	63.0
WP_011634523.1\|1549460_1550753_-\|portal	phage portal protein	C7BGG8	Burkholderia_phage	1.3e-90	41.7
WP_110332557.1\|1550749_1552459_-\|terminase	terminase large subunit	A0A0U2C138	Paracoccus_phage	1.6e-117	41.3
WP_011634525.1\|1552427_1552892_-\|terminase	phage terminase small subunit P27 family	Q6DMU4	Streptococcus_phage	3.0e-10	32.6
WP_041353779.1\|1553023_1553347_-	HNH endonuclease	B5WZZ4	Pseudomonas_phage	7.5e-32	58.6
WP_041353504.1\|1553433_1553814_-	hypothetical protein	NA	NA	NA	NA
WP_041353505.1\|1553815_1554001_-	hypothetical protein	NA	NA	NA	NA
WP_041353506.1\|1553997_1554177_-	hypothetical protein	NA	NA	NA	NA
WP_011634529.1\|1554169_1554409_-	hypothetical protein	NA	NA	NA	NA
WP_049753110.1\|1554717_1557051_-	hypothetical protein	A0A2D1GN57	Marinobacter_phage	1.5e-76	39.6
WP_011634531.1\|1557116_1557434_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_011634532.1\|1557440_1557719_+	XRE family transcriptional regulator	A0A1I9L2L2	Xanthomonas_phage	7.2e-07	42.9
WP_011634533.1\|1557840_1558146_-	hypothetical protein	Q37905	Pseudomonas_phage	1.9e-13	46.7
WP_011634534.1\|1558142_1558394_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_082211281.1\|1558750_1559485_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_041353781.1\|1559579_1560542_+	SppA protein	NA	NA	NA	NA
WP_011634537.1\|1560735_1561140_+	hypothetical protein	NA	NA	NA	NA
WP_146208360.1\|1561139_1561685_+	hypothetical protein	NA	NA	NA	NA
WP_011634539.1\|1561689_1562100_+	hypothetical protein	NA	NA	NA	NA
WP_166485003.1\|1562507_1562936_+	hypothetical protein	NA	NA	NA	NA
WP_041353508.1\|1563168_1563501_+	hypothetical protein	NA	NA	NA	NA
WP_011634542.1\|1563941_1564436_+	thermonuclease family protein	V5UN65	Mycobacterium_phage	5.7e-07	28.7
WP_011634543.1\|1565058_1565958_-	hypothetical protein	NA	NA	NA	NA
WP_166485004.1\|1566175_1566349_+	hypothetical protein	NA	NA	NA	NA
WP_166485005.1\|1566345_1566501_+	hypothetical protein	NA	NA	NA	NA
WP_011634544.1\|1566497_1566782_+	hypothetical protein	NA	NA	NA	NA
WP_146208358.1\|1566751_1567261_+	hypothetical protein	NA	NA	NA	NA
WP_011634546.1\|1567275_1567638_+	hypothetical protein	NA	NA	NA	NA
WP_011634547.1\|1567647_1568031_+	hypothetical protein	NA	NA	NA	NA
WP_041353510.1\|1568014_1568230_+	DUF4224 domain-containing protein	NA	NA	NA	NA
WP_011634548.1\|1568226_1568727_+	hypothetical protein	NA	NA	NA	NA
WP_011634549.1\|1568729_1569755_+\|integrase	tyrosine-type recombinase/integrase	C8CLF4	Xylella_phage	2.1e-96	56.2
WP_041353511.1\|1570111_1570378_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
1569828:1569872	attR	NA	NA	NA	NA
WP_011634551.1\|1570367_1571261_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_011634552.1\|1571323_1573168_+	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_011634553.1\|1573283_1574087_+	GTP cyclohydrolase I FolE2	NA	NA	NA	NA
WP_011634554.1\|1574253_1574874_+	YqhA family protein	K4K6D8	Caulobacter_phage	1.0e-13	26.9
WP_011634555.1\|1574902_1575643_-	pteridine reductase	M1NMS3	Moumouvirus	7.3e-06	28.8
WP_011634556.1\|1575715_1576891_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011634557.1\|1576887_1577631_-	purine phosphorylase	NA	NA	NA	NA
WP_011634558.1\|1577627_1579640_-	squalene--hopene cyclase	NA	NA	NA	NA
WP_041353783.1\|1579774_1580545_-	VacJ family lipoprotein	NA	NA	NA	NA
WP_011634560.1\|1580779_1581388_-	MotA/TolQ/ExbB proton channel family protein	NA	NA	NA	NA
WP_011634561.1\|1581687_1583034_+	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	5.3e-31	26.7
WP_011634562.1\|1583098_1583479_+	DUF423 domain-containing protein	NA	NA	NA	NA
WP_011634563.1\|1583539_1584724_+	RNA methyltransferase	NA	NA	NA	NA
WP_011634564.1\|1584733_1585222_+	disulfide bond formation protein B	NA	NA	NA	NA
WP_041353513.1\|1585504_1585894_+	RidA family protein	NA	NA	NA	NA
WP_011634566.1\|1586060_1586408_-	DUF488 domain-containing protein	NA	NA	NA	NA
WP_011634567.1\|1586462_1587137_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-26	38.4
WP_011634568.1\|1587133_1589683_+	ABC transporter permease	NA	NA	NA	NA
WP_011634569.1\|1589682_1590753_+	carotenoid 1,2-hydratase	NA	NA	NA	NA
WP_011634570.1\|1590832_1591075_+	sulfurtransferase TusA family protein	NA	NA	NA	NA
WP_011634571.1\|1591566_1592391_+	methane monooxygenase/ammonia monooxygenase subunit C	NA	NA	NA	NA
WP_011634572.1\|1592715_1593645_-	cytochrome-c peroxidase	NA	NA	NA	NA
WP_049753111.1\|1594685_1595675_+\|transposase	IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

1893166 : 1958743

Burkholderia_virus(37.5%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011634829.1\|1893166_1894498_-\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_011634830.1\|1894790_1895495_-	NapC/NirT family cytochrome c	NA	NA	NA	NA
WP_011634831.1\|1895497_1896205_-	cytochrome c family protein	NA	NA	NA	NA
WP_011634832.1\|1896266_1897388_-	hydroxylamine oxidation protein HaoB	NA	NA	NA	NA
WP_011634833.1\|1897384_1899097_-	hydroxylamine reductase	NA	NA	NA	NA
WP_011634834.1\|1899316_1903531_-	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	8.2e-70	27.0
WP_011634835.1\|1903687_1907767_-	DNA-directed RNA polymerase subunit beta	A0A146JCU1	Tokyovirus	4.4e-20	31.7
WP_011634836.1\|1908132_1908498_-	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_011634837.1\|1908583_1909099_-	50S ribosomal protein L10	NA	NA	NA	NA
WP_011634838.1\|1909465_1910161_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_011634839.1\|1910162_1910594_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_011634840.1\|1910710_1911244_-	transcription termination/antitermination protein NusG	NA	NA	NA	NA
WP_011634841.1\|1911262_1911607_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_011634842.1\|1911850_1913041_-	elongation factor Tu	A0A142CJQ8	Brazilian_marseillevirus	2.1e-18	26.1
WP_110332630.1\|1913588_1915748_-	type IV pilus secretin PilQ family protein	NA	NA	NA	NA
WP_011634844.1\|1915747_1916275_-	pilus assembly protein PilP	NA	NA	NA	NA
WP_011634845.1\|1916271_1916922_-	type 4a pilus biogenesis protein PilO	NA	NA	NA	NA
WP_011634846.1\|1916918_1917530_-	PilN domain-containing protein	NA	NA	NA	NA
WP_041353813.1\|1917526_1918633_-	pilus assembly protein PilM	NA	NA	NA	NA
WP_011634848.1\|1918809_1921122_+	penicillin-binding protein 1A	NA	NA	NA	NA
WP_011634849.1\|1921409_1922330_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	1.7e-44	34.3
WP_011634850.1\|1922466_1922688_-	prevent-host-death protein	NA	NA	NA	NA
WP_041353537.1\|1922876_1923167_-	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	1.0e-11	50.0
WP_082211262.1\|1925140_1925401_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_011634854.1\|1925545_1925827_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_011634855.1\|1925810_1926056_-	ParD-like family protein	NA	NA	NA	NA
WP_177165378.1\|1926326_1926464_-	hypothetical protein	NA	NA	NA	NA
WP_041353539.1\|1926471_1927374_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_166484999.1\|1927408_1928637_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	3.1e-126	78.4
WP_146208375.1\|1928739_1928928_-	hypothetical protein	NA	NA	NA	NA
WP_110332640.1\|1929187_1929541_-	flagellar protein FlaG	NA	NA	NA	NA
WP_110332639.1\|1929572_1929791_-	hypothetical protein	NA	NA	NA	NA
WP_011634860.1\|1930060_1930348_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_011634861.1\|1930531_1932007_-	flagellin	NA	NA	NA	NA
WP_166485011.1\|1932493_1933722_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.8e-126	78.4
WP_166484974.1\|1933833_1933977_-	hypothetical protein	NA	NA	NA	NA
WP_166485012.1\|1933966_1934629_-	hypothetical protein	NA	NA	NA	NA
WP_011634865.1\|1935508_1937335_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	3.9e-85	35.6
WP_041353815.1\|1937504_1938164_+	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_041353816.1\|1938369_1939077_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_011634868.1\|1939102_1940638_+	exopolyphosphatase	NA	NA	NA	NA
WP_166485013.1\|1940646_1941081_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_110332624.1\|1941126_1944555_-	pilus assembly protein PilY	NA	NA	NA	NA
WP_011634871.1\|1944569_1945421_-	pilus assembly protein PilX	NA	NA	NA	NA
WP_011634872.1\|1945446_1946511_-	PilW family protein	NA	NA	NA	NA
WP_110332623.1\|1946528_1947011_-	type IV pilus modification protein PilV	NA	NA	NA	NA
WP_011634874.1\|1947000_1947558_-	Tfp pilus assembly protein FimT/FimU	NA	NA	NA	NA
WP_011634876.1\|1947986_1948619_-	response regulator transcription factor	NA	NA	NA	NA
WP_011634877.1\|1948670_1950167_-	PAS domain-containing protein	NA	NA	NA	NA
WP_011634878.1\|1950832_1952380_-	O-antigen ligase family protein	NA	NA	NA	NA
WP_011634879.1\|1952522_1952930_-	pilin	NA	NA	NA	NA
WP_011634880.1\|1953057_1954830_-	gamma-glutamyltransferase	NA	NA	NA	NA
WP_049753120.1\|1955144_1956107_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_011634882.1\|1956164_1956674_-	hypothetical protein	NA	NA	NA	NA
WP_166484975.1\|1956947_1957740_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_082211263.1\|1957780_1958743_-\|transposase	IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_7

2105965 : 2163317

uncultured_Mediterranean_phage(15.38%)

tRNA,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049753120.1\|2105965_2106928_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_166485000.1\|2106969_2107767_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_011635016.1\|2107909_2110039_-	phosphate acetyltransferase	NA	NA	NA	NA
WP_074685632.1\|2110043_2110241_-	L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha	NA	NA	NA	NA
WP_011635017.1\|2110377_2111403_-	fructose-bisphosphate aldolase class I	A0A0K0KVJ8	Prochlorococcus_phage	1.4e-79	50.6
WP_011635018.1\|2111548_2111830_-	sugar nucleotide-binding protein	NA	NA	NA	NA
WP_041353558.1\|2111911_2112106_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5NR91	Burkholderia_phage	2.9e-15	66.1
WP_041353831.1\|2112760_2113054_+	BrnT family toxin	NA	NA	NA	NA
WP_011635021.1\|2113043_2113325_+	hypothetical protein	NA	NA	NA	NA
WP_160803637.1\|2113494_2113671_-	hypothetical protein	NA	NA	NA	NA
WP_166485016.1\|2113667_2114896_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.6e-125	77.7
WP_011635023.1\|2114879_2116862_-	type I polyketide synthase	D0R7J2	Paenibacillus_phage	2.4e-32	34.0
WP_011635024.1\|2117484_2119068_-	L-aspartate oxidase	NA	NA	NA	NA
WP_011635025.1\|2119317_2120238_+	branched-chain amino acid transaminase	NA	NA	NA	NA
WP_011635026.1\|2120262_2120472_+	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_011635027.1\|2120535_2121915_+	phosphomannomutase/phosphoglucomutase	A0A127AWJ1	Bacillus_phage	3.6e-51	29.6
WP_011635028.1\|2121951_2123559_+	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	4.2e-75	33.2
WP_011635029.1\|2123714_2125229_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_011635030.1\|2125308_2126454_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_110332570.1\|2126467_2127232_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-39	41.9
WP_011635032.1\|2127228_2128452_+	ABC transporter permease	NA	NA	NA	NA
WP_166485017.1\|2128492_2128663_+	hypothetical protein	NA	NA	NA	NA
WP_041353560.1\|2128740_2128926_+	hypothetical protein	NA	NA	NA	NA
WP_011635033.1\|2128967_2130425_+	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_011635034.1\|2130421_2130832_+	ATPase	NA	NA	NA	NA
WP_011635035.1\|2130828_2131110_+	AtpZ/AtpI family protein	NA	NA	NA	NA
WP_166485018.1\|2131155_2131449_+	ATP synthase subunit AtpR	NA	NA	NA	NA
WP_011635037.1\|2131470_2132163_+	F0F1 ATP synthase subunit A	NA	NA	NA	NA
WP_011635038.1\|2132165_2132444_+	F0F1 ATP synthase subunit C	NA	NA	NA	NA
WP_011635039.1\|2132450_2133221_+	ATP synthase subunit B	NA	NA	NA	NA
WP_011635040.1\|2133233_2134784_+	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_041353561.1\|2134788_2135658_+	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_049753164.1\|2136448_2139037_+	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	9.3e-32	24.2
WP_011635043.1\|2139071_2139551_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_049753165.1\|2139706_2140321_-	ribonuclease HII	D2TEQ2	Emiliania_huxleyi_virus	4.9e-24	43.0
WP_176752573.1\|2140344_2140779_-	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_011635046.1\|2140820_2141384_-	OmpH family outer membrane protein	NA	NA	NA	NA
WP_011635047.1\|2141409_2143686_-	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_011635048.1\|2143688_2145056_-\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_011635049.1\|2145074_2146316_-	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_011635050.1\|2146312_2147140_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_011635051.1\|2147174_2147966_-	di-trans,poly-cis-decaprenylcistransferase	R9W0U9	Flavobacterium_phage	2.6e-17	36.8
WP_011635052.1\|2147969_2148527_-	ribosome recycling factor	NA	NA	NA	NA
WP_011635053.1\|2148627_2149341_-	UMP kinase	NA	NA	NA	NA
WP_160803517.1\|2149397_2149541_-	hypothetical protein	NA	NA	NA	NA
WP_011635054.1\|2149891_2150776_-	elongation factor Ts	NA	NA	NA	NA
WP_011635055.1\|2150848_2151604_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_011635056.1\|2151818_2152547_-	fumarate/nitrate reduction transcriptional regulator Fnr	NA	NA	NA	NA
WP_107818360.1\|2152608_2152899_-	cytochrome c	NA	NA	NA	NA
WP_166485019.1\|2153157_2155236_-	TonB-dependent receptor	NA	NA	NA	NA
WP_041353562.1\|2155343_2155559_+	hypothetical protein	NA	NA	NA	NA
WP_164502684.1\|2156012_2156867_+	PHP domain-containing protein	NA	NA	NA	NA
WP_011635060.1\|2156989_2157622_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_011635061.1\|2157614_2158280_+\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_011635062.1\|2158355_2159558_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_011635063.1\|2159557_2160403_+	segregation/condensation protein A	NA	NA	NA	NA
WP_011635064.1\|2160368_2161019_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	4.0e-24	37.4
WP_011635065.1\|2161042_2162290_+	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_011635066.1\|2162428_2162632_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	8.9e-23	80.3
WP_011635067.1\|2163005_2163317_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-10	43.2

DBSCAN-SWA_8

2268953 : 2328602

Acinetobacter_phage(25.0%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011635159.1\|2268953_2269418_+\|tRNA	tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL	NA	NA	NA	NA
WP_011635160.1\|2269504_2270035_+	DUF488 domain-containing protein	NA	NA	NA	NA
WP_011635161.1\|2270220_2271057_+	FkbM family methyltransferase	NA	NA	NA	NA
WP_110332545.1\|2271367_2272858_-	glucose-6-phosphate dehydrogenase	M1UG55	Synechococcus_phage	3.9e-83	38.4
WP_011635163.1\|2272861_2273770_-	decarboxylating 6-phosphogluconate dehydrogenase	E3SJC4	Synechococcus_phage	6.1e-63	41.5
WP_041353571.1\|2273839_2274922_-	ADP-ribosylglycohydrolase family protein	NA	NA	NA	NA
WP_011635165.1\|2275039_2275339_-	YggU family protein	NA	NA	NA	NA
WP_011635166.1\|2275338_2275899_-	YggT family protein	NA	NA	NA	NA
WP_011635167.1\|2275971_2276784_-	pyrroline-5-carboxylate reductase	NA	NA	NA	NA
WP_041353849.1\|2276863_2277070_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_011635169.1\|2277088_2277553_-	hypothetical protein	NA	NA	NA	NA
WP_011635170.1\|2277889_2278024_+	50S ribosomal protein L34	NA	NA	NA	NA
WP_011635171.1\|2278060_2278426_+	ribonuclease P protein component	NA	NA	NA	NA
WP_011635172.1\|2278422_2278632_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	2.1e-19	58.0
WP_011635173.1\|2278722_2280591_+	membrane protein insertase YidC	NA	NA	NA	NA
WP_041353850.1\|2280661_2282017_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_011635175.1\|2282243_2282513_+	30S ribosomal protein S15	NA	NA	NA	NA
WP_011635176.1\|2282691_2284809_+	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_082211270.1\|2285224_2286772_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_011635178.1\|2286860_2288066_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_011635179.1\|2288083_2291278_+	multidrug efflux RND transporter permease subunit	NA	NA	NA	NA
WP_011635180.1\|2291546_2291888_-	DUF2007 domain-containing protein	NA	NA	NA	NA
WP_011635181.1\|2291916_2292657_-	ATPase	NA	NA	NA	NA
WP_011635183.1\|2293322_2294729_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_011635184.1\|2294780_2296010_-	outer membrane protein assembly factor BamB	NA	NA	NA	NA
WP_011635185.1\|2296012_2296651_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_011635186.1\|2296673_2297939_-\|tRNA	histidine--tRNA ligase	NA	NA	NA	NA
WP_011635187.1\|2297931_2299176_-	flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	NA	NA	NA	NA
WP_110332548.1\|2299209_2300247_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011635189.1\|2300275_2301067_-	type IV pilus biogenesis/stability protein PilW	NA	NA	NA	NA
WP_011635190.1\|2301112_2302252_-	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	NA	NA	NA	NA
WP_011635191.1\|2302289_2302715_-	nucleoside-diphosphate kinase	A0A167REB2	Powai_lake_megavirus	3.0e-20	40.6
WP_011635192.1\|2303012_2303429_-	nitrosocyanin	NA	NA	NA	NA
WP_011635193.1\|2303879_2305268_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	2.6e-25	31.2
WP_011635194.1\|2305279_2305984_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	1.7e-41	48.6
WP_011635195.1\|2305995_2306484_-	ribonuclease HI	J9Q745	Salmonella_phage	2.9e-35	47.3
WP_074456220.1\|2306543_2307278_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_011635197.1\|2307337_2308105_+	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_011635198.1\|2308408_2308981_-	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_011635199.1\|2309087_2310005_-	zinc finger, SWIM-type	NA	NA	NA	NA
WP_011635200.1\|2310008_2312702_-	DEAD/DEAH box helicase	A0A160DHD3	Gordonia_phage	1.2e-45	28.7
WP_011635201.1\|2313528_2314650_+	alkene reductase	NA	NA	NA	NA
WP_041353855.1\|2315274_2316843_+	alpha-D-glucose phosphate-specific phosphoglucomutase	NA	NA	NA	NA
WP_011635204.1\|2316878_2317718_+	cation transporter	NA	NA	NA	NA
WP_011635206.1\|2319469_2320414_+	agmatinase	NA	NA	NA	NA
WP_011635207.1\|2320425_2322384_+	biosynthetic arginine decarboxylase	NA	NA	NA	NA
WP_049753125.1\|2322375_2322879_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-17	37.8
WP_011635209.1\|2322898_2323192_-\|transposase	IS3 family transposase	A9YX41	Burkholderia_phage	2.5e-10	35.1
WP_011635210.1\|2323253_2323715_-	hypothetical protein	NA	NA	NA	NA
WP_082211272.1\|2323832_2324084_+\|transposase	transposase	NA	NA	NA	NA
WP_041353574.1\|2324031_2324895_-\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	5.6e-58	44.5
WP_166485020.1\|2325085_2326256_+\|transposase	IS3-like element ISNieu3 family transposase	A0A0P0I4A4	Acinetobacter_phage	8.1e-60	44.7
WP_049753126.1\|2326505_2327354_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_049753120.1\|2327639_2328602_+\|transposase	IS481 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

2481557 : 2528071

Enterobacteria_phage(20.0%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_166485000.1\|2481557_2482356_-\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_011635347.1\|2482879_2483221_+\|transposase	transposase	NA	NA	NA	NA
WP_011635348.1\|2483525_2484089_+	peroxiredoxin	NA	NA	NA	NA
WP_041353880.1\|2484225_2484765_+	CNP1-like family protein	NA	NA	NA	NA
WP_110332611.1\|2484792_2485560_-	slipin family protein	J3IZE5	Acanthamoeba_polyphaga_lentillevirus	1.5e-22	29.7
WP_041353882.1\|2485573_2486836_-	nodulation protein NfeD	NA	NA	NA	NA
WP_049753132.1\|2487011_2487614_-	NUDIX domain-containing protein	A0A1S6L1P8	Vibrio_phage	1.7e-16	32.0
WP_011635353.1\|2487797_2488712_-	Tim44 domain-containing protein	NA	NA	NA	NA
WP_041353587.1\|2488805_2489672_+	YicC family protein	NA	NA	NA	NA
WP_041353588.1\|2489765_2490848_-	tellurite resistance/C4-dicarboxylate transporter family protein	NA	NA	NA	NA
WP_110332610.1\|2491111_2491825_-	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_011635357.1\|2491851_2492850_-	phosphotransferase	NA	NA	NA	NA
WP_011635358.1\|2493014_2493323_+	accessory factor UbiK family protein	NA	NA	NA	NA
WP_011635359.1\|2493388_2494888_+	YifB family Mg chelatase-like AAA ATPase	NA	NA	NA	NA
WP_011635360.1\|2494906_2496304_-	replicative DNA helicase	A0A077SK18	Escherichia_phage	7.3e-116	51.7
WP_011635361.1\|2496409_2496865_-	50S ribosomal protein L9	NA	NA	NA	NA
WP_011635362.1\|2496883_2497162_-	30S ribosomal protein S18	NA	NA	NA	NA
WP_011635363.1\|2497203_2497512_-	primosomal replication protein N	NA	NA	NA	NA
WP_011635364.1\|2497513_2497948_-	30S ribosomal protein S6	NA	NA	NA	NA
WP_160803593.1\|2498543_2498702_-	hypothetical protein	NA	NA	NA	NA
WP_011635366.1\|2499221_2500109_-	acetylglutamate kinase	NA	NA	NA	NA
WP_011635367.1\|2500171_2500651_-	chemotaxis protein CheW	NA	NA	NA	NA
WP_011635368.1\|2500679_2501045_-	response regulator	W8CYM9	Bacillus_phage	3.7e-11	29.4
WP_041353589.1\|2501303_2501891_+	BON domain-containing protein	NA	NA	NA	NA
WP_110332609.1\|2501930_2503298_+	FAD-binding protein	NA	NA	NA	NA
WP_011635371.1\|2503391_2504288_-	protoheme IX farnesyltransferase	NA	NA	NA	NA
WP_011635372.1\|2504378_2504960_-	membrane protein	NA	NA	NA	NA
WP_011635373.1\|2504934_2505654_-	SURF1 family protein	NA	NA	NA	NA
WP_011635374.1\|2505746_2506592_-	cytochrome c oxidase subunit 3	NA	NA	NA	NA
WP_074456128.1\|2506783_2507314_-	cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_011635376.1\|2507436_2509014_-	cytochrome c oxidase subunit I	NA	NA	NA	NA
WP_011635377.1\|2509073_2509916_-	cytochrome c oxidase subunit II	NA	NA	NA	NA
WP_011635378.1\|2511339_2511558_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_011635379.1\|2511681_2512650_+	acetyl-CoA carboxylase carboxyltransferase subunit alpha	NA	NA	NA	NA
WP_041353590.1\|2512618_2513998_+\|tRNA	tRNA lysidine(34) synthetase TilS	E3T4I1	Cafeteria_roenbergensis_virus	8.0e-06	22.0
WP_011635381.1\|2514001_2515063_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	9.2e-87	48.5
WP_041353591.1\|2515059_2515956_+	dTDP-4-dehydrorhamnose reductase	A0A140G5S3	Enterobacteria_phage	8.2e-28	31.1
WP_011635383.1\|2515965_2516919_-	S49 family peptidase	NA	NA	NA	NA
WP_011635384.1\|2516946_2517609_-	OmpA family protein	G3M9Z0	Bacillus_virus	8.5e-06	32.6
WP_041353592.1\|2517820_2518657_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_011635386.1\|2518945_2520133_+\|transposase	IS256 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.8e-92	46.9
WP_166485000.1\|2520143_2520941_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_011635387.1\|2521098_2521974_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_011634897.1\|2522127_2523090_-\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_041353593.1\|2523830_2524055_-	hypothetical protein	NA	NA	NA	NA
WP_011635390.1\|2524051_2524375_-	hypothetical protein	NA	NA	NA	NA
WP_041353595.1\|2526665_2527715_-	Fic family protein	A0A1V0E025	Clostridioides_phage	6.1e-06	24.1
WP_166485033.1\|2527825_2528071_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_10

2550773 : 2630824

Planktothrix_phage(10.53%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011635411.1\|2550773_2552699_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_011635412.1\|2553080_2553545_-	flagellar protein FlgN	NA	NA	NA	NA
WP_011635413.1\|2553546_2553849_-	flagellar biosynthesis anti-sigma factor FlgM	NA	NA	NA	NA
WP_011635414.1\|2554128_2555622_+	ABC transporter permease	NA	NA	NA	NA
WP_011635415.1\|2555618_2557676_+	dipeptide ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.5e-21	34.1
WP_011635416.1\|2557672_2559280_+	peptide chain release factor 3	A0A2K9L6L3	Tupanvirus	9.3e-14	35.9
WP_011635417.1\|2559531_2560662_+	flagellar type III secretion system protein FlhB	NA	NA	NA	NA
WP_011635418.1\|2560709_2562794_+	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_011635419.1\|2562790_2564062_+	flagellar biosynthesis protein FlhF	NA	NA	NA	NA
WP_011635420.1\|2564054_2564948_+	AAA family ATPase	NA	NA	NA	NA
WP_011635421.1\|2564956_2565667_+	RNA polymerase sigma factor FliA	NA	NA	NA	NA
WP_193330458.1\|2566368_2567319_+\|transposase	IS630 family transposase	A0A1V0SCG6	Indivirus	1.3e-07	22.7
WP_041353597.1\|2567502_2567868_-	hypothetical protein	NA	NA	NA	NA
WP_166485011.1\|2567986_2569215_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.8e-126	78.4
WP_011635424.1\|2569612_2570176_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_011635425.1\|2570219_2571125_-	D-hexose-6-phosphate mutarotase	NA	NA	NA	NA
WP_011635426.1\|2571267_2574111_+	aconitate hydratase	NA	NA	NA	NA
WP_011635427.1\|2574231_2575503_-	glycerate kinase	NA	NA	NA	NA
WP_011635428.1\|2575499_2578337_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	5.5e-296	54.5
WP_041353888.1\|2578459_2579818_+	MFS transporter	NA	NA	NA	NA
WP_011635430.1\|2579818_2580286_+	single-stranded DNA-binding protein	F8TUL2	EBPR_podovirus	1.2e-43	57.0
WP_011635431.1\|2580488_2582279_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.8e-32	38.1
WP_011635432.1\|2582279_2583212_+	cytochrome c	NA	NA	NA	NA
WP_011635433.1\|2583257_2584217_-	polyamine aminopropyltransferase	NA	NA	NA	NA
WP_011635434.1\|2584216_2584624_-	adenosylmethionine decarboxylase	A0A1D7SGA8	Cyanophage	8.3e-12	36.3
WP_011635435.1\|2585017_2588458_-	acyl-[ACP]--phospholipid O-acyltransferase	A0A2H4PQM9	Staphylococcus_phage	1.0e-17	22.4
WP_011635436.1\|2588704_2591578_+	ribonucleoside-diphosphate reductase subunit alpha	A0A2H4P767	Pseudomonas_phage	2.0e-176	45.0
WP_011635437.1\|2591629_2592763_+	ribonucleotide-diphosphate reductase subunit beta	E5ER80	Bathycoccus_sp._RCC1105_virus	9.1e-32	27.7
WP_011635438.1\|2592910_2594275_+	transglycosylase SLT domain-containing protein	A0A172JIA8	Bacillus_phage	4.5e-09	31.7
WP_011635439.1\|2594262_2597883_-	urea carboxylase	NA	NA	NA	NA
WP_011635441.1\|2598828_2600367_+	amino acid permease	NA	NA	NA	NA
WP_011635442.1\|2600381_2601110_+	urea carboxylase-associated family protein	NA	NA	NA	NA
WP_011635443.1\|2601106_2601772_+	urea carboxylase-associated family protein	NA	NA	NA	NA
WP_110332592.1\|2601813_2604159_+	5-oxoprolinase/urea amidolyase family protein	NA	NA	NA	NA
WP_011635445.1\|2604290_2604734_+	universal stress protein	NA	NA	NA	NA
WP_011635446.1\|2604804_2605878_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_011635447.1\|2606449_2606776_+	thioredoxin TrxA	A0A1J0GW78	Streptomyces_phage	2.1e-18	46.7
WP_011635448.1\|2606989_2608249_+	transcription termination factor Rho	NA	NA	NA	NA
WP_041353600.1\|2608422_2608635_+	50S ribosomal protein L31	NA	NA	NA	NA
WP_011635449.1\|2609128_2609410_-	cell division protein FtsB	NA	NA	NA	NA
WP_011635450.1\|2609406_2610693_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	1.2e-144	62.1
WP_011635451.1\|2610981_2612676_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	8.2e-154	53.6
WP_011635452.1\|2612857_2613250_+	succinate dehydrogenase, cytochrome b556 subunit	NA	NA	NA	NA
WP_011635453.1\|2613243_2613597_+	succinate dehydrogenase, hydrophobic membrane anchor protein	NA	NA	NA	NA
WP_011635454.1\|2613598_2615362_+	succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
WP_011635455.1\|2615439_2616414_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_011635456.1\|2616630_2618937_+	DNA translocase FtsK	G1D482	Mycobacterium_virus	1.2e-83	49.3
WP_011635457.1\|2618996_2619617_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_011635458.1\|2619609_2620926_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	1.2e-80	39.2
WP_011635459.1\|2620953_2621628_-	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	3.3e-37	40.2
WP_011635460.1\|2621620_2622868_-	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_166485024.1\|2623006_2624029_-	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_166484975.1\|2624980_2625772_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_049753139.1\|2625841_2626804_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_166484975.1\|2626844_2627636_+\|transposase	IS5 family transposase	NA	NA	NA	NA
WP_041353602.1\|2627840_2629598_-	AAA family ATPase	NA	NA	NA	NA
WP_166485011.1\|2629596_2630824_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.8e-126	78.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_008341

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 17703

Leptospira_phage(20.0%)

integrase,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011630618.1\|221_3155_+\|transposase	Tn3 family transposase	NA	NA	NA	NA
WP_110332622.1\|3242_3728_-	endonuclease	NA	NA	NA	NA
WP_041353898.1\|3788_4688_-	hypothetical protein	S5W9D9	Leptospira_phage	5.3e-27	30.4
WP_110332621.1\|4731_5538_-	DNA-binding protein	NA	NA	NA	NA
WP_011630622.1\|5944_6559_+	recombinase family protein	E5FFF9	Burkholderia_phage	1.9e-36	44.8
WP_011630623.1\|6944_8207_-	conjugal transfer protein TrbI	NA	NA	NA	NA
WP_011630624.1\|8302_8761_-	conjugal transfer TrbH family protein	NA	NA	NA	NA
WP_011630625.1\|8757_9339_-	TrbG/VirB9 family P-type conjugative transfer protein	NA	NA	NA	NA
WP_011630626.1\|9522_10083_+	recombinase family protein	A0A219Y912	Aeromonas_phage	2.3e-28	43.1
WP_011630627.1\|10066_11722_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_011630628.1\|11711_12680_+	AAA family ATPase	NA	NA	NA	NA
WP_011630629.1\|12799_15715_+	ATP-dependent helicase	A7KV33	Bacillus_phage	4.1e-36	33.8
WP_011630630.1\|15714_17703_+	site-specific DNA-methyltransferase	A0A2L1IZ21	Streptomyces_phage	1.4e-40	31.1

DBSCAN-SWA_2

31685 : 47874

Salmonella_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011630644.1\|31685_32075_+	type II toxin-antitoxin system death-on-curing family toxin	D0R0D2	Streptococcus_phage	9.4e-13	33.9
WP_082211282.1\|32149_36892_-	DEAD/DEAH box helicase	A0A2H4UTW8	Bodo_saltans_virus	2.5e-35	29.5
WP_001138073.1\|36867_39840_-\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	0.0e+00	73.1
WP_001162012.1\|39842_40400_-	recombinase family protein	A0A1B0V7I5	Salmonella_phage	5.8e-48	81.3
WP_000993245.1\|40529_40742_-	DUF3330 domain-containing protein	NA	NA	NA	NA
WP_001087807.1\|40807_41044_-	broad-spectrum mercury transporter MerE	NA	NA	NA	NA
WP_001277463.1\|41040_41406_-	mercury resistance co-regulator MerD	NA	NA	NA	NA
WP_003055149.1\|41423_43106_-	mercury(II) reductase	A0A2K5B2C5	Erysipelothrix_phage	1.5e-38	27.8
WP_000522993.1\|43144_43552_-	organomercurial transporter MerC	NA	NA	NA	NA
WP_000732276.1\|43579_43855_-	mercury resistance system periplasmic binding protein MerP	NA	NA	NA	NA
WP_001294660.1\|43870_44221_-	mercuric transport protein MerT	NA	NA	NA	NA
WP_001166628.1\|44292_44748_+	Hg(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_011630646.1\|44754_45192_-	restriction endonuclease	NA	NA	NA	NA
WP_011630647.1\|45439_46072_-	SOS response-associated peptidase	A0A218MNF5	uncultured_virus	6.2e-38	40.0
WP_041353902.1\|46140_46572_+	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A2H4J538	uncultured_Caudovirales_phage	6.3e-26	47.2
WP_011630649.1\|46578_47874_+	Y-family DNA polymerase	A0A1W6JNT0	Morganella_phage	3.0e-87	41.8

DBSCAN-SWA_3

56414 : 59557

Vibrio_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_107818387.1\|56414_58736_+	toprim domain-containing protein	A0A2I7R3N6	Vibrio_phage	4.6e-14	29.2
WP_011630658.1\|58939_59557_+	AAA family ATPase	A2I303	Vibrio_virus	1.3e-13	31.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_008344

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_008341

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection