CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134535	Pseudopropionibacterium propionicum strain NCTC11666 genome assembly, chromosome: 1	9 crisprs	csa3,csm3gr7,cas10,cas6,csx10gr5,cas1,cas2,cas3,cas8u1,csb2gr5,csb1gr7,DEDDh,DinG,PD-DExK,WYL,cas7	1	16	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134535_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134535_1

118074-118154

Orphan

Consensus_repeat	Method
TCGCGACCCGGCTCAACCAGCTTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134535_1

>merge|LR134535|1|118074-118154|CRISPRCasFinder
TCGCGACCCGGCTCAACCAGCTTCAAAGTTGTGGTTTCGACAGGGACTGCTCCTTCGTCGCGACCCGGGTCAACCAGCTTC

>LR134535|1|1|118074-118154|CRISPRCasFinder
TCGCGACCCGGCTCAACCAGCTTC	AAAGTTGTGGTTTCGACAGGGACTGCTCCTTCG
TCGCGACCCGGGTCAACCAGCTTC

Protein	Signature genes	Signature genes Name	Protein_function
LR134535.1\|VEJ57280.1\|123197_124727_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57268.1\|106876_107188_+\|Antitoxin-of-toxin-antitoxin-stability-system	unknown	unknown	gnl\|CDD\|376852
LR134535.1\|VEJ57273.1\|115109_117515_-\|Lipase-precursor	unknown	unknown	gnl\|CDD\|238861
LR134535.1\|VEJ57275.1\|118199_119648_-\|CCA-adding-enzyme	unknown	unknown	gnl\|CDD\|131739
LR134535.1\|VEJ57270.1\|107978_108974_+\|Prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|234599
LR134535.1\|VEJ57282.1\|125906_126704_-\|Probable-siderophore-transport-system-ATP-binding-protein-YusV	unknown	unknown	gnl\|CDD\|224045
LR134535.1\|VEJ57278.1\|121383_122421_+\|ABC-type-taurine-transport-system,-periplasmic-component	unknown	unknown	gnl\|CDD\|223787
LR134535.1\|VEJ57269.1\|107249_107876_-\|Swarming-motility-protein-ybiA	unknown	unknown	gnl\|CDD\|378035
LR134535.1\|VEJ57266.1\|105994_106459_-\|Uncharacterized-HTH-type-transcriptional-regulator-yusO	unknown	unknown	gnl\|CDD\|224759
LR134535.1\|VEJ57281.1\|124811_125897_-\|vitamin-B12-transporter-protein-BtuF	unknown	unknown	gnl\|CDD\|238568
LR134535.1\|VEJ57283.1\|126700_127762_-\|Probable-ABC-transporter-permease-protein-HI_1471	unknown	unknown	gnl\|CDD\|376439
LR134535.1\|VEJ57284.1\|128027_128903_-\|1D-myo-inositol-2-acetamido-2-deoxy-alpha-D-glucopyranoside-deacetylase	unknown	unknown	gnl\|CDD\|274584
LR134535.1\|VEJ57271.1\|109677_111414_-\|Malto-oligosyltrehalose-trehalohydrolase	unknown	unknown	gnl\|CDD\|274114
LR134535.1\|VEJ57274.1\|117527_117953_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57276.1\|119885_120719_+\|Phospholipid-N-methyltransferase	unknown	unknown	gnl\|CDD\|379312
LR134535.1\|VEJ57279.1\|122417_123185_+\|Putative-aliphatic-sulfonates-transport-permease-protein-ssuC	unknown	unknown	gnl\|CDD\|223673
LR134535.1\|VEJ57277.1\|120715_121387_+\|Bicarbonate-transport-ATP-binding-protein-CmpD	unknown	unknown	gnl\|CDD\|224041
LR134535.1\|VEJ57265.1\|105523_106006_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57272.1\|111687_114225_-\|Maltooligosyl-trehalose-synthase	unknown	unknown	gnl\|CDD\|237740
LR134535.1\|VEJ57267.1\|106517_106880_+\|Uncharacterised-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
LR134535.1\|VEJ57268.1\|106876_107188_+\|Antitoxin-of-toxin-antitoxin-stability-system	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	1.90523e-07
LR134535.1\|VEJ57273.1\|115109_117515_-\|Lipase-precursor	gnl\|CDD\|238861	cd01823, SEST_like, SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxylic acid.	3.48787e-24
LR134535.1\|VEJ57275.1\|118199_119648_-\|CCA-adding-enzyme	gnl\|CDD\|131739	TIGR02692, putative_tRNA_nucleotidyltransferase, tRNA adenylyltransferase. The enzyme tRNA adenylyltransferase, also called tRNA-nucleotidyltransferase and CCA-adding enzyme, can add or repair the required CCA triplet at the 3'-end of tRNA molecules. Genes encoding tRNA include the CCA tail in some but not all bacteria, and this enzyme may be required for viability. Members of this family represent a distinct clade within the larger family pfam01743 (tRNA nucleotidyltransferase/poly(A) polymerase family protein). The example from Streptomyces coelicolor was shown to act as a CCA-adding enzyme and not as a poly(A) polymerase. [Protein synthesis, tRNA and rRNA base modification].	0
LR134535.1\|VEJ57276.1\|119885_120719_+\|Phospholipid-N-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.35706e-15
LR134535.1\|VEJ57270.1\|107978_108974_+\|Prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|234599	PRK00052, PRK00052, prolipoprotein diacylglyceryl transferase; Reviewed.	1.26783e-124
LR134535.1\|VEJ57278.1\|121383_122421_+\|ABC-type-taurine-transport-system,-periplasmic-component	gnl\|CDD\|223787	COG0715, TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism].	1.67244e-19
LR134535.1\|VEJ57269.1\|107249_107876_-\|Swarming-motility-protein-ybiA	gnl\|CDD\|378035	pfam08719, DUF1768, Domain of unknown function (DUF1768). This is a domain of unknown function. It is alpha helical in structure. The GO annotation for this protein suggests it is involved in nematode larval development and has a positive regulation on growth rate.	7.78297e-82
LR134535.1\|VEJ57266.1\|105994_106459_-\|Uncharacterized-HTH-type-transcriptional-regulator-yusO	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	1.02442e-11
LR134535.1\|VEJ57281.1\|124811_125897_-\|vitamin-B12-transporter-protein-BtuF	gnl\|CDD\|238568	cd01148, TroA_a, Metal binding protein TroA_a. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	7.90871e-95
LR134535.1\|VEJ57283.1\|126700_127762_-\|Probable-ABC-transporter-permease-protein-HI_1471	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	7.04923e-77
LR134535.1\|VEJ57284.1\|128027_128903_-\|1D-myo-inositol-2-acetamido-2-deoxy-alpha-D-glucopyranoside-deacetylase	gnl\|CDD\|274584	TIGR03445, mycothiol_MshB, N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase. Members of this protein family are N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase, also called 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, the MshB protein of mycothiol biosynthesis in Mycobacterium tuberculosis and related species. [Cellular processes, Detoxification].	4.70708e-65
LR134535.1\|VEJ57271.1\|109677_111414_-\|Malto-oligosyltrehalose-trehalohydrolase	gnl\|CDD\|274114	TIGR02402, Malto-oligosyltrehalose_trehalohydrolase, malto-oligosyltrehalose trehalohydrolase. Members of this family are the trehalose biosynthetic enzyme malto-oligosyltrehalose trehalohydrolase, formally known as 4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase (EC 3.2.1.141). It is the TreZ protein of the TreYZ pathway for trehalose biosynthesis, and alternative to the OtsAB system. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
LR134535.1\|VEJ57282.1\|125906_126704_-\|Probable-siderophore-transport-system-ATP-binding-protein-YusV	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	3.06169e-93
LR134535.1\|VEJ57279.1\|122417_123185_+\|Putative-aliphatic-sulfonates-transport-permease-protein-ssuC	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.36709e-44
LR134535.1\|VEJ57277.1\|120715_121387_+\|Bicarbonate-transport-ATP-binding-protein-CmpD	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.61084e-61
LR134535.1\|VEJ57272.1\|111687_114225_-\|Maltooligosyl-trehalose-synthase	gnl\|CDD\|237740	PRK14511, PRK14511, malto-oligosyltrehalose synthase.	0

>LR134535.1|VEJ57274.1|117527_117953_-|Uncharacterised-protein
MHHRTTATVTASVLCACLLLTGCSTRTRQRDLIRNDPMYSATWDGIEFLGAVDNDDDTLKPPPIATTRCFKTTKPTEETLHQVMTTAGQNGWLENEETRSKISRSARKNINSVNMNLIASTIVAGCTRYPETNFSISLAFT
>LR134535.1|VEJ57273.1|115109_117515_-|Lipase-precursor
MPKSTSTKRNLFLALILTLCLTFGTTQSASGDPATGSNKLAVITLLGDSFSAGNGAGDYYDKGPEKTYRSRNNWAHHYVNSLRDRGIATVFHNLAFSGATTTEVSQRQMGNVPTDSDLVMFSIGGNDKNSFGNIAINCFVLFTQSPEKCKESVEAAETFVQSGELRANTESILTQLEGHLPDKHAQIVLMGYPHLSIEHQNFLLFKCIEWDSSASGRCNEFYSYPTANRVRELVNKLTAVQEQLVHDWNANNNGSRHTVHYVSSLRSDFEGHETHPSTMLKNDYRWLNEFWETEGHLGESGKTEATFSSDVMEWYHPNKIGHQKMSEALNNTVDPASFTREANTSQAPVDVAIILDTSGEMFDNPQATRQKVKDAMDSFTKYNSNTRFALVTYSGFPVSGFQVWYGGDMPVVRSKFTSDPSAIQTTLGEIIPTPGGDNEEGVYSAMMEAFTRLDWRPGAQKRTVLIADAPPVDPEQRTGYTKADVEKKSYELDPVEVYAFDTNGWLETPELADLAKRTGGQIVKVNNPQTAPEAIAAAVEKANNKPFAWLDGPYNRAIGAPLSLDARGSYSKNGTITSYEWDLNGDGDFETSTTTPTLEHAWHEAYSGLVGLRITDSTGATSMATIKLDVSIDGDGVPDNTDNCPTVYNYGQTDYDGDGIGDACDDTPGIPTERQPGVFEGPPPTPGTPTPTANPTVITPTPAPTGSAIPTPSVSPTPAPTGIPSSSPTPTQNPTRPPTAPTTGPTQSPTGEPTQHPTQEPPPAPTTAPTPPNPTKQPTPTQPPSRSTTPPLRPGLPKTGS
>LR134535.1|VEJ57272.1|111687_114225_-|Maltooligosyl-trehalose-synthase
METNRTVPNSTYRMQLHGGFTFDDAAAWMPYLHSLGVTHLFCSPILQASPGSTHGYDVVDHSRISEECGGEEAFRRLSQAAHEQGIGVVVDVVPNHMAVPTPIWHNHALWDVLRRGPESAYAEWFDLDMTDSQAILMPVLGNRIGRELEHISFATDVINGEEQPVVAYYDQVFPVRPGTEDLPLDELLERQWYRLAYWRIGSEELNYRRFFDVDTLAAIRVEDPAIFEATHRKLIQLHAEGLIDGFRIDHIDGLANPRQYLADLQRATGGCWVVAEKILEYDEVLPTDFECAGTTGYDSLLRVAGLFHVPGSVPRLTDLWERMSGSGEGFASTVLNAKRTVVKESLFTELNRLVNIAMAICDGDIRLRDHTRRQLNHAIRELLYQFSRYRAYVEPGRATPESEREIIVEAATKAREYLTIDELDALDFVVALALGETGETDMGGAVTLPAPSKILNQLPGRAHNPSDLRAEFMVRFAQTCGPVMAKSKEDTAFYRWNRFIGVNEVGSDPNIIGINQDDFHGFCRTLAADWSTSMTTLSTHDTKRSEDVRARLAVLTEYPREWEHCVSELRAATSELRPALLDGGTELFLWQTLAATWTLPSTAAGAEAISADRLTRYLTKAMRESKLHTSWTSPDEDYESAVIEFATACLTTPEVGAALDAFTELTFPSVRANILGQKLIQLTMPGVPDLYQGCEVVDLSLVDPDNRRPIDYYRRSGVLTALDMNPPADLDAEKLLVTSRALLLRRDHPEAFRGPDADYRSVSLNTGHAVVFERGYRDSETPVAITVATRVQSGLNEEGWGDAELVLPNLRFRDVLTGREYPGGATPLADILDSLPVALLVHQVD
>LR134535.1|VEJ57271.1|109677_111414_-|Malto-oligosyltrehalose-trehalohydrolase
MRDITRPEVWAPDAGMVEVVVDGTGTIMARSDGGWWWSEPLPPGTLYQFRIDGGMLLPDPRSLSQPDGPHGPSRIVDPALFDRPATFSADLRGAVGYELHIGTFTPEGTFEAAITHLDHLVDLGVQAVEVMPVADFPGEQGWGYDGVGQYAVHAAYGGPEGLVAFIDACHARGLGVILDVVHNHQGPEGNYLAQFGPYFTSAHHTPWGDAINLDQPGSSEVRDFLLGACRQWLVKYQVDGLRLDAVHEFQDDSPRHYLAELSDEARVWERETGREFTLFAESDRNQPTTVSPIGSVPGALGMDGQWADDVHHALHSFFTGERDGYYVDFGTAEVLQQALTRVFIHEGGFSTFRGQDWGAPVDPASGLYDGHSFVVSLQNHDQVGNRAVGDRISHSTPPGCQAAAAALYLLSPFTPLLFMGEEWASSTPFPFFSHLGPELGPLVTEGRAREFERMGWDAEIPDPQSPATRESAALRWDEVTEPDHARMLAWYQELLRLRRDRPELASGSLAEVSVEVLDEDTVLMRRGATTVAATRARDRLVEIPVEGEVLVAWGEYGPVPGGHAVTGPGSLVIDTRTD
>LR134535.1|VEJ57270.1|107978_108974_+|Prolipoprotein-diacylglyceryl-transferase
MTILELTFPHLDPVAITIGPVRIHWYAIMYLLAFAMAYGLMRLRLRHQPFASITKPSAWVPADIEDLLLYGIAGVILGGRLGYVLFYQLGYYATHPLDVFKVWDGGMSFHGGAIGVILGMAFFAWRRSRPFLQVADFLVPSVPIGLAAGRIGNFINGELWGRAAPPDLPWAMRFPTGGNVLRHPSQLYQALLEGVLLFVLLWLYARKPRLRGQVAAAFLFGYGLFRFIAEYWREPDSQLGFLSLGLSMGQWLSVPMILAGVALWLWARKRGISDVQEPADDPGKETACENPEENAGDDTEEKSTGAVEESPETVDEAGETPAEKDETPSQS
>LR134535.1|VEJ57269.1|107249_107876_-|Swarming-motility-protein-ybiA
MYDLDWLLARTARKQKTKYLYFWGHRPTANGTLSGSCLSQWWASPFEVDGVRYATAEHWMMAGKARLFGDDGAADRIVEASHPDCAKRLGREVRGFDQDRWDERRFDLVVEGNRAKFSQHPDLREFLLGTGERVLVEASPVDRIWGAGLAADDDRIADPHSWRGLNLLGFALMTVRDELAETTSPEPGSHTILNTRINDKLPVDALHE
>LR134535.1|VEJ57268.1|106876_107188_+|Antitoxin-of-toxin-antitoxin-stability-system
MKPVAASVYTIATIACVETITREVSTRELRSQLSDVLGRAMYAGERIGVTRNGKLAAVVVGVEDLEALEAYEMDQDIAAYRRSKEEDDGTRISLAELRAELPS
>LR134535.1|VEJ57267.1|106517_106880_+|Uncharacterised-protein
MPWWIALLNTVAALLSVVFAAITLVRPNQFIPPTLRRQTDRFAAATYAVRAIPLGLAVIVVVWAAPAGTATALLLGVACAAQVGDLVLGVVHRVWGMAGGAGSGVVFHAVGVAAAAGVVG
>LR134535.1|VEJ57266.1|105994_106459_-|Uncharacterized-HTH-type-transcriptional-regulator-yusO
MGDGDKILNSTSVRLGILGVQVTELARQRLEPLGLAPKQVGLMAFVDSRTKASQREIASGMRVAPSLVVTLVDQLEALKAVTRIRRPGDRRVQEISLTEVGRKLLSEALVVVRALDEDLTAHLADGDHRALDRTLEAVENGRWLPDSMGRGSAD
>LR134535.1|VEJ57265.1|105523_106006_+|Uncharacterised-protein
MDHETARRGVLDAIPLLASKRSEKKVIAALWEMGYDRAAAEQLTLLVPSALAWPLCRRAGLRNFPDHFVVSDDRGREIRVPVADLHYFTAALRLGIDTFENGWLEEVPRRVYEQVVRRSAELDAVGKTLEQGGDLSGSTMQALMIYVKDAEAFVRSGSVG
>LR134535.1|VEJ57275.1|118199_119648_-|CCA-adding-enzyme
MPDLTQAQRNAVSELLRISQVIGDLGSRFDAAGHRLYLVGGSVRDAMLGGLGHDLDFTTSARPDETHAILRDFTPATWDIGRDFGTIGAMKKEGGKEWQLEVTTFRADAYEPGSRKPVVAFGERIEEDLVRRDFTVNAMAVDVVAGEFVDPWGGLRDLADGVLRTPAPAEVSFGDDPLRMMRAARFASRLGFRVAPEVQDAMREMAERITIVSAERVQAELTGLLLTDSPREGLDLLVRTGLAEHFLPELPALRLERDEHMRHKDVYAHSLTVLEQAIDLEKARGHQPDIVNRLAALLHDIGKPATRRFEGSKVTFHHHDVVGAKLVTKRLKALKYPTATVKSVAKLVELHLRFHGYGDASWSDSAVRRYVRDAGDELERLHILTRADCTTRNRNKATRLRRNYEELEWRIDELAAQEEIKAIRPDLDGAQIMEILGIKPGPDVGKAYKFLLNHRMDHGPLPEDEARDLLLNWWKDQQSQGT
>LR134535.1|VEJ57276.1|119885_120719_+|Phospholipid-N-methyltransferase
MSTESKQAGVKGERSGPEAGRMQGHWLLAKLGKRILRPGGRALTAKLLEQAKPSGDDDIVELGPGVGATAEVLLRANPRSYRGVDPNPEGRDTVKNILKKHPRADYVVADARETGLEDASADLVVGEAMLTIQDDAGKNAIVAEAARLLRPGGRYAIHEMAWLPDHTDEERETARRELSRVIKVGARPLTLEGWKELLATHGLEAEWHDRAPLHLLEPRRIVSDEGLWGALRFWNNARRLPGASDRLKAMRQGFQLQGKLMGGIVILARKPGAASTR
>LR134535.1|VEJ57277.1|120715_121387_+|Bicarbonate-transport-ATP-binding-protein-CmpD
MTTGLVLDDVTLVRGGNTLIDGLDVVVAPGQTLAVTGASGAGKTTLLKAISGLSPCDRGSVTRPEGRLAQVFQEPRLLPWYSAHRNVALVVGGETPDLIAQQWLARVDLQQATHLYPRQLSGGMRQRVAIARAMATSPTLLLVDEPFSALDKPLATALRTDLVQLLAEQEVVTVWVTHDPEEADDVSHLHLHLDGPPGTWRLTTDTGEPAPDPEEPTPHKETS
>LR134535.1|VEJ57278.1|121383_122421_+|ABC-type-taurine-transport-system,-periplasmic-component
MKRRSLFTLTGLGLLGTAGLAACSGGKPAGEGSTSASKLETLRVHVPTTLAFMAPMASFGTFGKLDGLVGKTDVQNWASVDVMKSLVVGGETDLVATPSYAAANLFNKGLPIRLVAMTVWGMLYILGPEGSSAQGIEGLKGKKVGVPLPNNMPDLVFRYLMTQSGIPLEGGAEGIEVVPYDQAPELVKALMSGQVEYAVLPEHVATVAQNQAKQSGKNLDRTANLQEVWAKVTGGQARFPMAGVVMPQKLVDSNQALVAGVLNELEEAVAKVNALDEKAVAAITAKTEVPEAVVKNVIPRLQLEMVPAQKAKTELEDFYTRLTTLSPDIVGGKMPADDFYLTDPR
>LR134535.1|VEJ57279.1|122417_123185_+|Putative-aliphatic-sulfonates-transport-permease-protein-ssuC
MNPAENEAPRWRVVLLWWLGLALVLLAWEAASWSQPRYVLPGPAATWEALLGLIRDEELGAGVLLTLQRALGGLGIACLIGLPWGWAAGTWRPVEELTASWTQLLMAIPPIVIVVVGMLWLGPSPSVVLLVVALVTMPLLVTSLRDAVTNVDPDLLEMARLFRFGLWGTVRRVIIPAVVPPVLSAVTVAVGQSIRLTVMAELLSTTTGLGAEVQQARTNLETADVFALSAVMAVLTLGLELLFLRPLRNRLARYR
>LR134535.1|VEJ57280.1|123197_124727_-|Uncharacterised-protein
MTISKALDLDRDGWNDEAVEAIRSHQHNMLNGGSLDEIVEGFRAEARIQRHRGEAGALARACDSAQQAVLLGRLPAASRELAAPACLELAACRIRRGDPAGTQAIAGFTTHPDAGIAGWAWRLLGEAALLAERPFEAVATLLNAVAENQRGKDKYHEAGTRVLLLLAFSRAGHLEDADRLAFRYGAPSDAPQGLLGIRFLLARAEHEHRSGRIGEALGTLKVAETRLGATSGLGVLRRELLTIRASCLDDWCQPDEADRLRAEAGKLPLPAHLATSANASHTLRDAQNATRWLGEIPHPGANTRTDPQAVAALLRDLAALPQRKPDHAAVVCRLLDSLAGRPGLERDEALLLLEAGSLLAESGPEHRVAAERLLRRALVRLEFLEGAEQWLAQARVTLGQLLPDSERDQALNLLVRGIQGLDEQRFQMLNRSYRDGWLTRREHPAIARAIELASGTDATLAADLITFSRVAGVLVPRDDRQVPLVPVPRLRYIDGTESRLGSTGSCNFL
>LR134535.1|VEJ57281.1|124811_125897_-|vitamin-B12-transporter-protein-BtuF
MITRRARAVAWLTLPLIALSACSSPTQPTTSTSGSAGGSGQVTVTNCGKELTLPSQAKKMYVNDGNIIALALAAGGAKEITAVSSMGRDVPILKAKYGAETVDGLNDVSKEYPTLESILANSPDLVVAGWNYGFSEGKNLTPDILSEKGIPSYLLTESCRQEGTTKRGIVDPWEAVRTDITNLGTITGHSDVAKTAVEDMDTRLKAVQGAAQPEKKPVVFLFDSAKDNVFTSGKYGAPQAIIEAAGGTNATADIEDTWTNVNWERLATANPDVIALVEYPGQSYQEKIDALKSHPATKDLTAVKEERFVNLPYAMWTESPLNIDAAEYLRKAFEKHGLAPASDVSTHLEMPADLPGRDKLS
>LR134535.1|VEJ57282.1|125906_126704_-|Probable-siderophore-transport-system-ATP-binding-protein-YusV
MTALKADNLTCSIGRRVIVSGIDLDVQPGTMTALVGVNGVGKSTLMRVLAGIRPATTGHVEVDGKDLSQLRPRERARLMAFVAQEEAAPEDLSLSEMVALGRLPHLMPWQVGGSNEKRIVAECLEMVGLAHLANRRCGHLSGGERRRAMLAKGLAQGTDLLLLDEPTNHLDVHHQLHLLQTMRATGRTIVASIHDLDLAMGWFDRIVMLADGGIHAAGTPEEVMTAVNLESAFKVRARQVPAVGDGVQHLVIDGLVPPEPIDPEP
>LR134535.1|VEJ57283.1|126700_127762_-|Probable-ABC-transporter-permease-protein-HI_1471
MASLKTARRVLKLLTLPIVVVVLALTAVSIIHSVNIGSEALDQDAIWQVIVSRLQGVSSGNKAVETIVWDLRLPRALLAVVVGAGLGIAGCAMQTLVRNPLADPYLLGVSSGASVGATAVITFGILSGFGLWSTSIGALFGALGAALAVYLVAMAQGGLTPIRLVLAGVVLSSAFSAIASFLVFKGPDPRAAQSVLYWLLGSVSGAQWDRLPLATGVVVICLVLLLLGSGWLDALAWGPDAAAALGIPVGVLRQGLFLLLAVLVGVLVAVSGGIGFVGLVIPHLCRMVVGSLHRRLLPVAAAVGGLFLLWVDVLSRVIVAPAEVPLGVVTGLIGAPVFLIVMGRRNYGFGGGS
>LR134535.1|VEJ57284.1|128027_128903_-|1D-myo-inositol-2-acetamido-2-deoxy-alpha-D-glucopyranoside-deacetylase
MFVHAHPDDESSQSPATMSRYVDEGARVTLVTCTLGELGEILVPEWEHYTPEELGAKRVDELAKALKIVGVTDHVWLGGKGRYHDSGMATDDEGRAIPRDELPDGAFWAADLLEASDHLVALIRDRRPQVVATYDQNGNYGHPDHIQAHRVTMYATLLAGVPSYRPNLGEPWRVSRVLWISPNPQAWSKAAEKAHELGMPLPEGMDEEAMRRRFAIDPRHIVAVIPYEGRADLCQAALEAHRSQVDPEHPLWKMFRFMRTVEGTGEAYRLAAGVPFPGDSPADDLFAGLDV

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Crispr_ID: LR134535_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134535_3

391645-392048

TypeIII

Consensus_repeat	Method
GTCTGGAAGCACCGCGAACCTCGAAGCGGATTGAAAC	CRISPRCasFinder
GTCTGNAANCACCGCGAACCTNNAAGCGGATTGAAAC	CRT
GTCTGGAAGCACCGCGAACCTCGAAGCGGATTGAAACACG	PILER-CR

5 spacers

csm3gr7,csx10gr5,cas10,cas6,cas1,cas2

The CRISPR arrays of LR134535_3

>merge|LR134535|3|391645-392048|CRISPRCasFinder,CRT,PILER-CR
ATCTGAAACCACCGCGAACCTTAAAGCGGATTGAAACGCCTCTCGAATCAAAATACCATTGATCATAATGTGGTCTGGAAGCACCGCGAACCTCGAAGCGGATTGAAACACGGGGAGCTCTCCGTTGTTAGAGCCTTTCGGCGTCTGGAAGCACCGCGAACCTCGAAGCGGATTGAAACTTGTTGCAATATTCACACCCCGGGCATCCGGAGTGCCTGAAAGTCTGGAAGTACCGCGAACCTCGAAGCGGATTGAAACACGCGTTAGTTTCGCATGATGATCTGGGCATGGTGGACGGTCTGGAAGCACCGTGAACCTTAAAGCGGATTGAAACTACTCCACCCGGGTGTTCCCCCCGATGACGTCGGTCTGAAACCACCGCGAACCTTAAAGCGGATTGACGT

>LR134535|3|3|391645-392048|CRISPRCasFinder
ATCTGAAACCACCGCGAACCTTAAAGCGGATTGAAAC	GCCTCTCGAATCAAAATACCATTGATCATAATGTG
GTCTGGAAGCACCGCGAACCTCGAAGCGGATTGAAAC	ACGGGGAGCTCTCCGTTGTTAGAGCCTTTCGGC
GTCTGGAAGCACCGCGAACCTCGAAGCGGATTGAAAC	TTGTTGCAATATTCACACCCCGGGCATCCGGAGTGCCTGAAA
GTCTGGAAGTACCGCGAACCTCGAAGCGGATTGAAAC	ACGCGTTAGTTTCGCATGATGATCTGGGCATGGTGGACG
GTCTGGAAGCACCGTGAACCTTAAAGCGGATTGAAAC	TACTCCACCCGGGTGTTCCCCCCGATGACGTCG
GTCTGAAACCACCGCGAACCTTAAAGCGGATTGACGT

>LR134535|3|1|391645-392048|CRT
ATCTGAAACCACCGCGAACCTTAAAGCGGATTGAAAC	GCCTCTCGAATCAAAATACCATTGATCATAATGTG
GTCTGGAAGCACCGCGAACCTCGAAGCGGATTGAAAC	ACGGGGAGCTCTCCGTTGTTAGAGCCTTTCGGC
GTCTGGAAGCACCGCGAACCTCGAAGCGGATTGAAAC	TTGTTGCAATATTCACACCCCGGGCATCCGGAGTGCCTGAAA
GTCTGGAAGTACCGCGAACCTCGAAGCGGATTGAAAC	ACGCGTTAGTTTCGCATGATGATCTGGGCATGGTGGACG
GTCTGGAAGCACCGTGAACCTTAAAGCGGATTGAAAC	TACTCCACCCGGGTGTTCCCCCCGATGACGTCG
GTCTGAAACCACCGCGAACCTTAAAGCGGATTGACGT

>LR134535|3|1|391717-391905|PILER-CR
GTCTGGAAGCACCGCGAACCTCGAAGCGGATTGAAACACG	GGGAGCTCTCCGTTGTTAGAGCCTTTCGGC
GTCTGGAAGCACCGCGAACCTCGAAGCGGATTGAAACTTG	TTGCAATATTCACACCCCGGGCATCCGGAGTGCCTGAAAGTC
TGGAAGTACCGCGAACCTCGAAGCGGATTGAAACACG

Protein	Signature genes	Signature genes Name	Protein_function
LR134535.1\|VEJ57503.1\|393752_394037_+\|CRISPR-associated-endoribonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
LR134535.1\|VEJ57501.1\|392332_392503_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57497.1\|388093_389290_+\|CRISPR-associated-RAMP-protein,-Csx10-family	csx10gr5	cls000715_csx10gr5_CAS-III-D	gnl\|CDD\|187879
LR134535.1\|VEJ57496.1\|387470_388097_+\|RAMP-superfamily	csm3gr7	cls000184_csm3gr7_CAS-III-D	gnl\|CDD\|187857
LR134535.1\|VEJ57498.1\|389291_390623_+\|CRISPR-associated-RAMP-protein,-SSO1426-family	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|377130
LR134535.1\|VEJ57491.1\|378882_380250_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57499.1\|390615_391056_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57506.1\|396391_396556_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|379366
LR134535.1\|VEJ57493.1\|382503_383454_+\|Uncharacterized-conserved-protein-(DUF2276)	cas6	pfam10040_cas6_CAS-III:CAS-IV	unknown
LR134535.1\|VEJ57504.1\|395413_395698_+\|Transcription-factor-WhiB	unknown	unknown	gnl\|CDD\|376791
LR134535.1\|VEJ57510.1\|398637_399405_+\|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	unknown	unknown	gnl\|CDD\|224054
LR134535.1\|VEJ57502.1\|393288_393762_+\|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187766
LR134535.1\|VEJ57495.1\|385959_387474_+\|CRISPR-associated-protein-Cas10/Cmr2,-subtype-III-B	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|274208
LR134535.1\|VEJ57490.1\|377488_378886_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57507.1\|396552_397014_+\|putative-endoribonuclease-L-PSP	unknown	unknown	gnl\|CDD\|100006
LR134535.1\|VEJ57492.1\|380686_382501_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|380122
LR134535.1\|VEJ57494.1\|383446_385948_+\|CRISPR-associated-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
LR134535.1\|VEJ57505.1\|395759_396395_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57509.1\|397606_398230_+\|putative-NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239518
LR134535.1\|VEJ57508.1\|397010_397628_+\|UV-endonuclease	unknown	unknown	gnl\|CDD\|223255

Protein	Function_ID	Function_description	E-value
LR134535.1\|VEJ57503.1\|393752_394037_+\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	5.05313e-20
LR134535.1\|VEJ57506.1\|396391_396556_+\|Uncharacterised-protein	gnl\|CDD\|379366	pfam13783, DUF4177, Domain of unknown function (DUF4177).	0.000301818
LR134535.1\|VEJ57497.1\|388093_389290_+\|CRISPR-associated-RAMP-protein,-Csx10-family	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	9.14663e-07
LR134535.1\|VEJ57496.1\|387470_388097_+\|RAMP-superfamily	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	4.08968e-14
LR134535.1\|VEJ57498.1\|389291_390623_+\|CRISPR-associated-RAMP-protein,-SSO1426-family	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	6.60016e-08
LR134535.1\|VEJ57507.1\|396552_397014_+\|putative-endoribonuclease-L-PSP	gnl\|CDD\|100006	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	1.7469e-57
LR134535.1\|VEJ57508.1\|397010_397628_+\|UV-endonuclease	gnl\|CDD\|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	1.51393e-101
LR134535.1\|VEJ57504.1\|395413_395698_+\|Transcription-factor-WhiB	gnl\|CDD\|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	2.6144e-22
LR134535.1\|VEJ57502.1\|393288_393762_+\|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	5.59379e-45
LR134535.1\|VEJ57495.1\|385959_387474_+\|CRISPR-associated-protein-Cas10/Cmr2,-subtype-III-B	gnl\|CDD\|274208	TIGR02577, thermophile-specific_DNA_repair_system, CRISPR-associated protein Cas10/Cmr2, subtype III-B. This model represent a Crm2 family of the CRISPR-associated RAMP module, a set of six genes recurring found together in prokaryotic genomes. This gene cluster is found only in species with CRISPR repeats, usually near the repeats themselves. Because most of the six (but not this family) contain RAMP domains, and because its appearance in a genome appears to depend on other CRISPR-associated Cas genes, the set is designated the CRISPR RAMP module. This protein, typified by TM1794 from Thermotoga maritima, is designated Crm2, for CRISPR RAMP Module protein 2.	5.68519e-09
LR134535.1\|VEJ57510.1\|398637_399405_+\|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.35416e-77
LR134535.1\|VEJ57492.1\|380686_382501_+\|Uncharacterised-protein	gnl\|CDD\|380122	pfam18145, SAVED, SMODS-associated and fused to various effectors sensor domain. Predicted to function as a sensor domain, sensing nucleotides or nucleotide derivatives generated by SMODS and other nucleotide synthetase domains. The sensing of ligands by SAVED is predicted to activate effectors deployed by a class of conflict systems which are reliant on the on the production and sensing of the nucleotide second messengers.	2.42993e-07
LR134535.1\|VEJ57494.1\|383446_385948_+\|CRISPR-associated-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	1.88558e-45
LR134535.1\|VEJ57509.1\|397606_398230_+\|putative-NUDIX-hydrolase	gnl\|CDD\|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	1.02297e-47

>LR134535.1|VEJ57499.1|390615_391056_+|Uncharacterised-protein
MPEQKRTTETRYLSGQGEVEWSQLRKEASELTCAWADYDGFHIGPCPDEAPPYSHIWGWSRDGEVLLRGRIDAGRVIAGWLRKTPSGGEKEKEVPTVTRQVLTWKPDHERLKINSAGEKANWPEKMQSVEVLGENPVTFMKEENPS
>LR134535.1|VEJ57498.1|389291_390623_+|CRISPR-associated-RAMP-protein,-SSO1426-family
MILTYIRVTIRPLGPWRVGAVGQDQAALETLRDNAGRPALPPSSLAGSFRAGIDEAARELLMGQEKTKNGKQDFRASTLWFLGTRLTSGEDRQPEIRRRTATAVDRNRRAARNHGSHDVEEVYGTETIQLYLRHEGDPAEALRLLGKWRVTIGGGISTGLGRAKVTAIWYRTLDLSQPADLLARVSLQDTGPDALDALLQGGADHKVNTGESPTLLEATIRVEGLNLPTQKLADQLRPEDHWFHGTRWKGILRGRVEYIGRSLGLDVCGAEDQQWRGCGDCAVCEVFGSGETGVGRWSFHFTPLKPDHPAGRTRNAIDRFTGGVAEKKLFPEKTVTSRARLVIGQLSGVEEHHAWVLRALLLALRDLQEGYLGIGGRSSTGLGSVRFEKLRLGEEFQRFGMAATTPEAVEGITEAEIELERTHRSLKEKEEKEEKEKEEMQHA
>LR134535.1|VEJ57497.1|388093_389290_+|CRISPR-associated-RAMP-protein,-Csx10-family
MSWWRVTVTSEQAIVVGTGATRAFHTPSLGYIPGSTLRGALAAAWRIRYGDPDSAFRETFDQSVRFGPLLAVTGDVASQSVLRRKYAPGDGEYVDCAFEDAGDAVGEHLKGDVIWGDKNALKVVTTTAIDPEKRTALDGNLFSREAHRRRQTYHGLIHGDENLVGRLAELESASIGGRRSVMGRARIRIEPTPPPELPASGDVVLRTLSPTILLDEAGGPSLDWEKAKAFEGFDVVGAWAGRVAGEGISGWHMASGTPKPGDIAIAPGAVVKLREPDRDKVLKLLERGLGTRRAEGFGWLEQVTKPWRPPGGKPGEEQTGGVATPDLDAMLGWPLEDRRAVAGWLQELREGDGTEPLESRRAWLNLTEGRRAAARRVIRDTPQAQRNPWASRLREGRN
>LR134535.1|VEJ57496.1|387470_388097_+|RAMP-superfamily
MTTTKTTIELKIRFNTAFRISQGYGQGEVDDVIDEENPLPATSLKGVMRDAARMVLPGKRQGDKYVDHHLVDAVFGKRGSDNSPWNFSDGKLDHPDDPRERIRVRSRVAIDEQRRTRAGALLFAEELHADRATATISLTQPLPPEELDKHVALLHVAARLVDGIGADRRRGLGWVSITTDADDIEAMVDRIERARDGQAGNEQVRSES
>LR134535.1|VEJ57495.1|385959_387474_+|CRISPR-associated-protein-Cas10/Cmr2,-subtype-III-B
MTCFSSIGVKQIQGYLARSRRLWGRRGASDMLAYLTDTTGAADRIEERSFDTAGEILQGFPGVTVNDEAIDVDSVLNIRGEDPGEVRKATEALALNIKLHLPAAHVHTSLREATGYGDVIRDEDRDMAAETRQSPPSMIEFPLAHHCDECSSGMASEETSVGDETTRLCGDCASRAPREGRNRLLNWSRLGSVQQGFMVEQVMLRELRKQEKFGNLKQVENFDELAQLGDLGSEGSRTHTDNHVATIFADGNGFGKLFRELRAAAAESEDGLQELRRVSKVVKDSTKQALQKAIEEITDDRVAAANRMPAVPHILGGDDVLVTVPATKAWPFLIAFLKHLEQESGSDTFGLGAGKVSFSAGMVICKLAYPIGDQVELAAALLRTAKEAVRGNDWSFAWLDVTNEGPKPPRRFLTLDDWGRIEELRDLARRLGDDERGNAARATLRQELRIRDEKDRTLHLRHRAGRLPGVADLLNAVFGRNWERATNQGTEELLTVLNIMRWYA
>LR134535.1|VEJ57494.1|383446_385948_+|CRISPR-associated-protein
MNEYAYVEEIDEDHVRVWPLTDSELTWNGEKVLTRKDGFTLEIEMCLGYEKGNPGYYVVETDELPEVCMLESPISGTSVGSKRSKTWRKELWIPEGSGGLEGALRDKAYSHDFDLLEVEPKRLCWGGEGLGRWIETAKEEVERKAARKKAGETREKLKEFHDGGNAFINPYTFVPLPDTVKRDKPHGHARAVEGGLTGYLDVEFAFRSPLMMPVDWNIPEETTVTGTRIEERVTVPGSSVRGAVRSLFEVISSSCLSILDPDYRPAHRASLEMRPDKRLAVVDEVDSDGRVISVLPTNRVVWIRAEALWHLFDGAAGLRSGVRISFDESAIYERSFGGNKGKPVKREQLKPEGEATLTEGGDWVVHVADAGTKGDHPADHIYVAVGKLETTPIRLGEMTWENYRELCRYSVDVTGGGLAPSAPAWDAEEWAGVAVMVRHTDRNGGHVVTAIGKRRKSDGALAPGDSVWITTGSEGGERVVTGLTMSSSWRELGKGPIRDRLPDESLLPCRDPDELCPACATFGFIEARAEGQRRDQAEHNAYASHLRFGAFETDAPVPLRLVLPPPTRSPRPSAGAFYLEHLKVEGDNREAGVAEFGKPASRWGGRLDSPRMRRIAGRKFYWHGQEPEDTTPTPRQVRRNHYPAEGANNCREVRRWITEKPPVLRGRIHFENIDARQLGLLMLALEPRELAKRAGITVNGELATHLGGGKGLGFGTAVGRITATCVQDAAGRYRAGAGKVEVDPWGAAMQVIDPEALWITGLVKALGTGSVPTDRIWYPTMGNFTQRGSYAQQQRFDKSFEYYAKFSGGKNKEIRMRTLPRIDDPIQYMSNEN
>LR134535.1|VEJ57493.1|382503_383454_+|Uncharacterized-conserved-protein-(DUF2276)
MGSPRSLPAVRVRIWQVLLRAETGERHLTPTPSGIHAMVSSWLHRSPGGDGEPHSEEHRYAVRWRQVSEFAVLVELRLFDDFLTPLLVDRVAFGNRERLGMVTLRVEGIQEVASVNLAEITGRPSKGWRLRFPEGVTFKRGDVFMPWPDPYLLLGSIQRRLALICGRDRDEQRLPREVMASVFPTQVELQSVRWTEGDPSRASLRDVRVALGEVDWLCTGDAATSSLIDRLLQVGELTGIGARTAWGAGVLEIADRVPMRAIATGNKRRSRRGPSRPSGIGRTGRTPFPRFAGESGEWGFDDERPGGSRDRRVGSE
>LR134535.1|VEJ57492.1|380686_382501_+|Uncharacterised-protein
MTSSRPPGRGNGPVFISYHQKSGAADAEFIETYLRAGGIVPWRDIRDLEAGTVERNITQAFEEGLSGGVLLLSSGISESSFVPKTEAPLLVGAHKADPEGFQLHIINTFRKPGSPDECDFKAPGKQLKTKYPEAEQLNDHLQRRLLHSDDKGGKPVSELNLVLRDLLRNRLKVRRPQLGDGEIEIGLQTRPEPNHLPADGRTVPEADLHIRLRQDAATQIPEELDYRCLQQALPVLIDELHAARIRRVLFRGGCHPSLAWALGVALPHAREIEHFTWRDTYGKDWASADEPAERSTSIHLETLNPDGSRRALGFAPDEIPSGAELRRALCGDAPAKNAVVLLAADDLRPQPLLALAEKLDDSPVLVINLHTPSADGAKKWIDHAEGAGLARRVGEILRRLRDLAKLHLAISAPAAMAALTARWCNTLTIDFYELGNTGMGAREYIRVLRTESGNKSPITGVFPQGVPQVDEVRKLINLTPHDVTYYPEAGEPFTWAAPEGPDQWVRRQEQSEELPSLRVQGLEIPVTRIRQGTIAPVPDPMPGVGYIVPRISAETARRPDFFFPHGEVRGQGGGIIGCRRLGCFEAVSNRVRPYLELLDPVPQD
>LR134535.1|VEJ57491.1|378882_380250_+|Uncharacterised-protein
MSETDKQIVIEALGGGPVQVGTGGPAPAGNVTLPLRTVVVVVNPAEPEEAPCCLVADVDESQEELADLYGGATAGLASRAAGWDGPGRVGKLPLAPDDEDMAEAVARLGVVRWLQEWSPLPLDWRLLRLEELTLVTSLTGRLADEPDRLPELAELCRYFHDHLDEEEFAPLTGLLGDALEQVANRFPLSGESGDWARQLLATWPPGEETASPGRLDVEFIDRFTPELALAAGPEGWGKLVESATVDWEQLPRGWVATGENNARWVLDLDVEGKIHCAVAVDGPQEVRWFGGVSWGRELNEDDRLGFDLFSGDAPEPVLSGELGYDPRTRGWAGSVTGTAAQTARLKQGREAGAGRSLRVRRDTTLRETLAPVAAAARRWSVRGVSALRLLTAADDRDLRAGAVAALTEAASCWETAGWKRDAEACRGLLRKVGSGEWKDWVDLTVAEQWLLHPRS
>LR134535.1|VEJ57490.1|377488_378886_+|Uncharacterised-protein
MSKSFAQWCGQWLERLPKWERYAPKGFGVTVNLVVKRLLHPGVTAGPEWAGVERGERIGDERGRELLAWLDGRRDVVEKLLALLRTGVDDAMARARQQGLDVTISRVAEALAVAIGSKWKQAVVLTDLEVESVWETFLRNSVPLGRRMGRREFAGYQGLFDRLWEDEGRASLAAEPYGRYGLGENERPPLVVEERENVFLGLQRSVFSRFSFAAREPYVKGSADEIARREVSRTCARLGLIDESARIALRSLHAGLMSGPSGPGWKPPGATPGKRDWNDDLLPLGEETDPQGDPALEWEGIHAGLAALAQAMIATFTGRTLQGQYLKLAEKMEEAHQDAMRRAWHECFRLDMTGRPVTEAKASKIVKHAIYGGIPSGQKQRRDPRRLTGGHKDEIPPEDAGGSAEAGRLALFERALEWLRADEERARAVVRGDEDATAEYERAAAELGLPSIDEVCHHMDQDWKQ
>LR134535.1|VEJ57501.1|392332_392503_-|Uncharacterised-protein
MAGLMCSRIALSTIRSRTEGMSRKRSPFFFGITTRVRSEGRNVPARSSSASSSSLS
>LR134535.1|VEJ57502.1|393288_393762_+|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO
MAFTVRSKQPPRDVLNAALSFLYTILLGECVTALRATGLDPDMGVLHADHDTRPSLALDLMEEFRPLVVDHVVVTAARKHVLTASHGREVADKGGIFLTAAGRELMLDAYERRMLTCVAGALDDFRSTRRGHLYQQAQRLRAAIMDPEQKWTGLAWR
>LR134535.1|VEJ57503.1|393752_394037_+|CRISPR-associated-endoribonuclease-Cas2
MAMMHLAAYDVHEDQRRAQLSALLQAYGDRIQYSVFLLGITPEELVEIQSRAAGIIDENTDSLWIVRQCAACWEEARTLGQAHPPARVLHYTVM
>LR134535.1|VEJ57504.1|395413_395698_+|Transcription-factor-WhiB
MSLGELGEWTLRAKCRDMEDVLFPESKDQRRVRNICMSCPVRMECLAEALDNRVQWGVWGGMTERERRRLLRSRPDITSWREVLLTYGRLEEAS
>LR134535.1|VEJ57505.1|395759_396395_+|Uncharacterised-protein
MSKPRWVAGGWGWVCCSGAGWFRLGSLVPRDPAQPASRRALAIRLDRLQGRESAARLNQLQGRESAARLNRLWGGEFAIRLDRLWGGEFAARLDRLWGGEFAARLDRLWGGEFAARLDRLWGGESAIRLNRLWGGESAARLDRLWGGESAIRLNQLGEGCSRPGLTSFKEGELVEPACERQRAGRVETSCACPGSRGRSGPGGAFDGRLGA
>LR134535.1|VEJ57506.1|396391_396556_+|Uncharacterised-protein
MTKWEYLTAPILSHVSQQILNNFGADGWELVTVAPGPTPETMVGYFKRPLEEGR
>LR134535.1|VEJ57507.1|396552_397014_+|putative-endoribonuclease-L-PSP
MSTPTQRLAELGLSLPPVAKPLAAYTPAITVGNQVWVSGQLPLRDGKLIATGRLGDAVEPAEGAEAAKVAALNALAAVADQAGGLDNVARILKAVVFVASTTDFTAQPQVANGASELLGEVFGTPHVRSAVGVAVLPIDAPVEVELVAELAAR
>LR134535.1|VEJ57508.1|397010_397628_+|UV-endonuclease
MTAALIGSRLAAAYPDARCDLDHRSPFELLVAVVLSAQTTDVRVNQVTPELFTRYPDAEHLAEAEQDDVEEIISSLGLYRSKARSLTGLARALVADHDGRVPDSLDELVKLPGVGRKTANVVLGNAFGIPGITPDTHVIRVSNRLGWVHSTEPDDVERAVGALFPPSEWVMLCHRIIWHGRRCCRARKPACTVCPVEDLCPSSQA
>LR134535.1|VEJ57509.1|397606_398230_+|putative-NUDIX-hydrolase
MSQLSGLTTALRDGVAGPLGQFGRAPGDARPAAVLILLTDEPDPAVLFTERAGGLRAHAGQISFPGGGAETGETPVATALREAREEVGLDAGLVTVLGQLPTAWVPASGYEVTPVVALWSEPLPLAPVDPGEVANVLQLRISQLSDPVNRVTATIPGGYRGPGFQLGDLFIWGMTAHLLDVTLRVAGWERSWDRDREVPVPGRFLRD
>LR134535.1|VEJ57510.1|398637_399405_+|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA
MTTAISFQNVTKDYATSKGIVRALRGLDLEIPQGVIYGLLGPNGAGKTTALEIAVGLREATGGLARTMGLDPVRENAEVRNRISIQPQNATGFDLLTGEELLDIWSALYPNPRPAEELIRLLDMSGYIDRQLRRLSGGQRQRVNLALALIGGVNVTVLDEPSTGLDPMARADLWDALRHLKQEGMTIILSTHDMEEAEVLCDCLAIIDAGAVVAEGSPSELIADAERRHQGPDRFRGLTDVFFQAAGRSFHQQNK

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Crispr_ID: LR134535_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134535_4

394327-394795

TypeIII

Consensus_repeat	Method
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	PILER-CR
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	CRISPRCasFinder
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	CRT

6 spacers

cas2,cas1,csm3gr7,csx10gr5,cas10

The CRISPR arrays of LR134535_4

>merge|LR134535|4|394327-394795|PILER-CR,CRISPRCasFinder,CRT
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAACTTGATCAACTCCTGGCAGTCCTTGCTTACTCTCTCGTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAACCGAAGGCGCAGCTGCTTCAGGTAGCGCTTCTTGACAGTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAACGTTTCTGCCCTCGTCCGGGTACGCGTAACAAGCTGGGTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAACAGGAGCGATATTTCTCAAACGCCCCCCTTAGCACCGTGTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAACGGCGTCCTGATCGTCTTGGCACGCTATCTCAGCAGTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAACTCGCCTCGTTCATGGATTCGATCACGCTCTCCGTCTGAAACCACCGCGAACCTCAAAGCGGATTTGAAT

>LR134535|4|2|394327-394726|PILER-CR
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	TTGATCAACTCCTGGCAGTCCTTGCTTACTCTCTC
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	CGAAGGCGCAGCTGCTTCAGGTAGCGCTTCTTGACA
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	GTTTCTGCCCTCGTCCGGGTACGCGTAACAAGCTGG
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	AGGAGCGATATTTCTCAAACGCCCCCCTTAGCACCGT
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	GGCGTCCTGATCGTCTTGGCACGCTATCTCAGCA
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC

>LR134535|4|4|394327-394795|CRISPRCasFinder
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	TTGATCAACTCCTGGCAGTCCTTGCTTACTCTCTC
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	CGAAGGCGCAGCTGCTTCAGGTAGCGCTTCTTGACA
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	GTTTCTGCCCTCGTCCGGGTACGCGTAACAAGCTGG
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	AGGAGCGATATTTCTCAAACGCCCCCCTTAGCACCGT
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	GGCGTCCTGATCGTCTTGGCACGCTATCTCAGCA
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	TCGCCTCGTTCATGGATTCGATCACGCTCTCC
GTCTGAAACCACCGCGAACCTCAAAGCGGATTTGAAT

>LR134535|4|2|394327-394795|CRT
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	TTGATCAACTCCTGGCAGTCCTTGCTTACTCTCTC
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	CGAAGGCGCAGCTGCTTCAGGTAGCGCTTCTTGACA
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	GTTTCTGCCCTCGTCCGGGTACGCGTAACAAGCTGG
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	AGGAGCGATATTTCTCAAACGCCCCCCTTAGCACCGT
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	GGCGTCCTGATCGTCTTGGCACGCTATCTCAGCA
GTCTGAAACCACCGCGAACCTCAAAGCGGATTGAAAC	TCGCCTCGTTCATGGATTCGATCACGCTCTCC
GTCTGAAACCACCGCGAACCTCAAAGCGGATTTGAAT

Protein	Signature genes	Signature genes Name	Protein_function
LR134535.1\|VEJ57503.1\|393752_394037_+\|CRISPR-associated-endoribonuclease-Cas2	cas2	COG1343_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|224262
LR134535.1\|VEJ57501.1\|392332_392503_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57497.1\|388093_389290_+\|CRISPR-associated-RAMP-protein,-Csx10-family	csx10gr5	cls000715_csx10gr5_CAS-III-D	gnl\|CDD\|187879
LR134535.1\|VEJ57496.1\|387470_388097_+\|RAMP-superfamily	csm3gr7	cls000184_csm3gr7_CAS-III-D	gnl\|CDD\|187857
LR134535.1\|VEJ57513.1\|401580_403611_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57498.1\|389291_390623_+\|CRISPR-associated-RAMP-protein,-SSO1426-family	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|377130
LR134535.1\|VEJ57506.1\|396391_396556_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|379366
LR134535.1\|VEJ57499.1\|390615_391056_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57500.1\|391341_391953_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57504.1\|395413_395698_+\|Transcription-factor-WhiB	unknown	unknown	gnl\|CDD\|376791
LR134535.1\|VEJ57510.1\|398637_399405_+\|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	unknown	unknown	gnl\|CDD\|224054
LR134535.1\|VEJ57502.1\|393288_393762_+\|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187766
LR134535.1\|VEJ57495.1\|385959_387474_+\|CRISPR-associated-protein-Cas10/Cmr2,-subtype-III-B	cas10	mkCas0133_cas10_CAS-III	gnl\|CDD\|274208
LR134535.1\|VEJ57512.1\|400321_401581_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57507.1\|396552_397014_+\|putative-endoribonuclease-L-PSP	unknown	unknown	gnl\|CDD\|100006
LR134535.1\|VEJ57494.1\|383446_385948_+\|CRISPR-associated-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
LR134535.1\|VEJ57505.1\|395759_396395_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57509.1\|397606_398230_+\|putative-NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239518
LR134535.1\|VEJ57508.1\|397010_397628_+\|UV-endonuclease	unknown	unknown	gnl\|CDD\|223255
LR134535.1\|VEJ57511.1\|399422_400235_+\|ABC-type-transport-system-involved-in-multi-copper-enzyme-maturation,-permease-component	unknown	unknown	gnl\|CDD\|378925

Protein	Function_ID	Function_description	E-value
LR134535.1\|VEJ57503.1\|393752_394037_+\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|224262	COG1343, COG1343, CRISPR-associated protein Cas2 [Defense mechanisms].	5.05313e-20
LR134535.1\|VEJ57506.1\|396391_396556_+\|Uncharacterised-protein	gnl\|CDD\|379366	pfam13783, DUF4177, Domain of unknown function (DUF4177).	0.000301818
LR134535.1\|VEJ57497.1\|388093_389290_+\|CRISPR-associated-RAMP-protein,-Csx10-family	gnl\|CDD\|187879	cd09748, Cmr3_III-B, CRISPR/Cas system-associated RAMP superfamily protein Cmr3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; This protein is a subunit of Cmr complex.	9.14663e-07
LR134535.1\|VEJ57496.1\|387470_388097_+\|RAMP-superfamily	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	4.08968e-14
LR134535.1\|VEJ57498.1\|389291_390623_+\|CRISPR-associated-RAMP-protein,-SSO1426-family	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	6.60016e-08
LR134535.1\|VEJ57507.1\|396552_397014_+\|putative-endoribonuclease-L-PSP	gnl\|CDD\|100006	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	1.7469e-57
LR134535.1\|VEJ57508.1\|397010_397628_+\|UV-endonuclease	gnl\|CDD\|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	1.51393e-101
LR134535.1\|VEJ57504.1\|395413_395698_+\|Transcription-factor-WhiB	gnl\|CDD\|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	2.6144e-22
LR134535.1\|VEJ57502.1\|393288_393762_+\|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	5.59379e-45
LR134535.1\|VEJ57495.1\|385959_387474_+\|CRISPR-associated-protein-Cas10/Cmr2,-subtype-III-B	gnl\|CDD\|274208	TIGR02577, thermophile-specific_DNA_repair_system, CRISPR-associated protein Cas10/Cmr2, subtype III-B. This model represent a Crm2 family of the CRISPR-associated RAMP module, a set of six genes recurring found together in prokaryotic genomes. This gene cluster is found only in species with CRISPR repeats, usually near the repeats themselves. Because most of the six (but not this family) contain RAMP domains, and because its appearance in a genome appears to depend on other CRISPR-associated Cas genes, the set is designated the CRISPR RAMP module. This protein, typified by TM1794 from Thermotoga maritima, is designated Crm2, for CRISPR RAMP Module protein 2.	5.68519e-09
LR134535.1\|VEJ57510.1\|398637_399405_+\|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.35416e-77
LR134535.1\|VEJ57494.1\|383446_385948_+\|CRISPR-associated-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	1.88558e-45
LR134535.1\|VEJ57509.1\|397606_398230_+\|putative-NUDIX-hydrolase	gnl\|CDD\|239518	cd03426, CoAse, Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid sythesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules.	1.02297e-47
LR134535.1\|VEJ57511.1\|399422_400235_+\|ABC-type-transport-system-involved-in-multi-copper-enzyme-maturation,-permease-component	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	1.4134e-07

>LR134535.1|VEJ57503.1|393752_394037_+|CRISPR-associated-endoribonuclease-Cas2
MAMMHLAAYDVHEDQRRAQLSALLQAYGDRIQYSVFLLGITPEELVEIQSRAAGIIDENTDSLWIVRQCAACWEEARTLGQAHPPARVLHYTVM
>LR134535.1|VEJ57502.1|393288_393762_+|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO
MAFTVRSKQPPRDVLNAALSFLYTILLGECVTALRATGLDPDMGVLHADHDTRPSLALDLMEEFRPLVVDHVVVTAARKHVLTASHGREVADKGGIFLTAAGRELMLDAYERRMLTCVAGALDDFRSTRRGHLYQQAQRLRAAIMDPEQKWTGLAWR
>LR134535.1|VEJ57501.1|392332_392503_-|Uncharacterised-protein
MAGLMCSRIALSTIRSRTEGMSRKRSPFFFGITTRVRSEGRNVPARSSSASSSSLS
>LR134535.1|VEJ57500.1|391341_391953_-|Uncharacterised-protein
MLPDRPPCPDHHAKLTRVSIRFEVRGTSRLSGTPDARGVNIATSFNPLRGSRCFQTPKGSNNGELPVFQSASRFAVLPDHIMINGILIREAFQSALRFAVVSDPTPWHAVLTSPVAAVLHTTPPHPLQQADRTCPQRGKTPSQVPYTSEAVFGCSPTPLSEGVSKMPGRGEPGVFVGVYLGPGPVPRRGIRPRARSGLLFGRR
>LR134535.1|VEJ57499.1|390615_391056_+|Uncharacterised-protein
MPEQKRTTETRYLSGQGEVEWSQLRKEASELTCAWADYDGFHIGPCPDEAPPYSHIWGWSRDGEVLLRGRIDAGRVIAGWLRKTPSGGEKEKEVPTVTRQVLTWKPDHERLKINSAGEKANWPEKMQSVEVLGENPVTFMKEENPS
>LR134535.1|VEJ57498.1|389291_390623_+|CRISPR-associated-RAMP-protein,-SSO1426-family
MILTYIRVTIRPLGPWRVGAVGQDQAALETLRDNAGRPALPPSSLAGSFRAGIDEAARELLMGQEKTKNGKQDFRASTLWFLGTRLTSGEDRQPEIRRRTATAVDRNRRAARNHGSHDVEEVYGTETIQLYLRHEGDPAEALRLLGKWRVTIGGGISTGLGRAKVTAIWYRTLDLSQPADLLARVSLQDTGPDALDALLQGGADHKVNTGESPTLLEATIRVEGLNLPTQKLADQLRPEDHWFHGTRWKGILRGRVEYIGRSLGLDVCGAEDQQWRGCGDCAVCEVFGSGETGVGRWSFHFTPLKPDHPAGRTRNAIDRFTGGVAEKKLFPEKTVTSRARLVIGQLSGVEEHHAWVLRALLLALRDLQEGYLGIGGRSSTGLGSVRFEKLRLGEEFQRFGMAATTPEAVEGITEAEIELERTHRSLKEKEEKEEKEKEEMQHA
>LR134535.1|VEJ57497.1|388093_389290_+|CRISPR-associated-RAMP-protein,-Csx10-family
MSWWRVTVTSEQAIVVGTGATRAFHTPSLGYIPGSTLRGALAAAWRIRYGDPDSAFRETFDQSVRFGPLLAVTGDVASQSVLRRKYAPGDGEYVDCAFEDAGDAVGEHLKGDVIWGDKNALKVVTTTAIDPEKRTALDGNLFSREAHRRRQTYHGLIHGDENLVGRLAELESASIGGRRSVMGRARIRIEPTPPPELPASGDVVLRTLSPTILLDEAGGPSLDWEKAKAFEGFDVVGAWAGRVAGEGISGWHMASGTPKPGDIAIAPGAVVKLREPDRDKVLKLLERGLGTRRAEGFGWLEQVTKPWRPPGGKPGEEQTGGVATPDLDAMLGWPLEDRRAVAGWLQELREGDGTEPLESRRAWLNLTEGRRAAARRVIRDTPQAQRNPWASRLREGRN
>LR134535.1|VEJ57496.1|387470_388097_+|RAMP-superfamily
MTTTKTTIELKIRFNTAFRISQGYGQGEVDDVIDEENPLPATSLKGVMRDAARMVLPGKRQGDKYVDHHLVDAVFGKRGSDNSPWNFSDGKLDHPDDPRERIRVRSRVAIDEQRRTRAGALLFAEELHADRATATISLTQPLPPEELDKHVALLHVAARLVDGIGADRRRGLGWVSITTDADDIEAMVDRIERARDGQAGNEQVRSES
>LR134535.1|VEJ57495.1|385959_387474_+|CRISPR-associated-protein-Cas10/Cmr2,-subtype-III-B
MTCFSSIGVKQIQGYLARSRRLWGRRGASDMLAYLTDTTGAADRIEERSFDTAGEILQGFPGVTVNDEAIDVDSVLNIRGEDPGEVRKATEALALNIKLHLPAAHVHTSLREATGYGDVIRDEDRDMAAETRQSPPSMIEFPLAHHCDECSSGMASEETSVGDETTRLCGDCASRAPREGRNRLLNWSRLGSVQQGFMVEQVMLRELRKQEKFGNLKQVENFDELAQLGDLGSEGSRTHTDNHVATIFADGNGFGKLFRELRAAAAESEDGLQELRRVSKVVKDSTKQALQKAIEEITDDRVAAANRMPAVPHILGGDDVLVTVPATKAWPFLIAFLKHLEQESGSDTFGLGAGKVSFSAGMVICKLAYPIGDQVELAAALLRTAKEAVRGNDWSFAWLDVTNEGPKPPRRFLTLDDWGRIEELRDLARRLGDDERGNAARATLRQELRIRDEKDRTLHLRHRAGRLPGVADLLNAVFGRNWERATNQGTEELLTVLNIMRWYA
>LR134535.1|VEJ57494.1|383446_385948_+|CRISPR-associated-protein
MNEYAYVEEIDEDHVRVWPLTDSELTWNGEKVLTRKDGFTLEIEMCLGYEKGNPGYYVVETDELPEVCMLESPISGTSVGSKRSKTWRKELWIPEGSGGLEGALRDKAYSHDFDLLEVEPKRLCWGGEGLGRWIETAKEEVERKAARKKAGETREKLKEFHDGGNAFINPYTFVPLPDTVKRDKPHGHARAVEGGLTGYLDVEFAFRSPLMMPVDWNIPEETTVTGTRIEERVTVPGSSVRGAVRSLFEVISSSCLSILDPDYRPAHRASLEMRPDKRLAVVDEVDSDGRVISVLPTNRVVWIRAEALWHLFDGAAGLRSGVRISFDESAIYERSFGGNKGKPVKREQLKPEGEATLTEGGDWVVHVADAGTKGDHPADHIYVAVGKLETTPIRLGEMTWENYRELCRYSVDVTGGGLAPSAPAWDAEEWAGVAVMVRHTDRNGGHVVTAIGKRRKSDGALAPGDSVWITTGSEGGERVVTGLTMSSSWRELGKGPIRDRLPDESLLPCRDPDELCPACATFGFIEARAEGQRRDQAEHNAYASHLRFGAFETDAPVPLRLVLPPPTRSPRPSAGAFYLEHLKVEGDNREAGVAEFGKPASRWGGRLDSPRMRRIAGRKFYWHGQEPEDTTPTPRQVRRNHYPAEGANNCREVRRWITEKPPVLRGRIHFENIDARQLGLLMLALEPRELAKRAGITVNGELATHLGGGKGLGFGTAVGRITATCVQDAAGRYRAGAGKVEVDPWGAAMQVIDPEALWITGLVKALGTGSVPTDRIWYPTMGNFTQRGSYAQQQRFDKSFEYYAKFSGGKNKEIRMRTLPRIDDPIQYMSNEN
>LR134535.1|VEJ57504.1|395413_395698_+|Transcription-factor-WhiB
MSLGELGEWTLRAKCRDMEDVLFPESKDQRRVRNICMSCPVRMECLAEALDNRVQWGVWGGMTERERRRLLRSRPDITSWREVLLTYGRLEEAS
>LR134535.1|VEJ57505.1|395759_396395_+|Uncharacterised-protein
MSKPRWVAGGWGWVCCSGAGWFRLGSLVPRDPAQPASRRALAIRLDRLQGRESAARLNQLQGRESAARLNRLWGGEFAIRLDRLWGGEFAARLDRLWGGEFAARLDRLWGGEFAARLDRLWGGESAIRLNRLWGGESAARLDRLWGGESAIRLNQLGEGCSRPGLTSFKEGELVEPACERQRAGRVETSCACPGSRGRSGPGGAFDGRLGA
>LR134535.1|VEJ57506.1|396391_396556_+|Uncharacterised-protein
MTKWEYLTAPILSHVSQQILNNFGADGWELVTVAPGPTPETMVGYFKRPLEEGR
>LR134535.1|VEJ57507.1|396552_397014_+|putative-endoribonuclease-L-PSP
MSTPTQRLAELGLSLPPVAKPLAAYTPAITVGNQVWVSGQLPLRDGKLIATGRLGDAVEPAEGAEAAKVAALNALAAVADQAGGLDNVARILKAVVFVASTTDFTAQPQVANGASELLGEVFGTPHVRSAVGVAVLPIDAPVEVELVAELAAR
>LR134535.1|VEJ57508.1|397010_397628_+|UV-endonuclease
MTAALIGSRLAAAYPDARCDLDHRSPFELLVAVVLSAQTTDVRVNQVTPELFTRYPDAEHLAEAEQDDVEEIISSLGLYRSKARSLTGLARALVADHDGRVPDSLDELVKLPGVGRKTANVVLGNAFGIPGITPDTHVIRVSNRLGWVHSTEPDDVERAVGALFPPSEWVMLCHRIIWHGRRCCRARKPACTVCPVEDLCPSSQA
>LR134535.1|VEJ57509.1|397606_398230_+|putative-NUDIX-hydrolase
MSQLSGLTTALRDGVAGPLGQFGRAPGDARPAAVLILLTDEPDPAVLFTERAGGLRAHAGQISFPGGGAETGETPVATALREAREEVGLDAGLVTVLGQLPTAWVPASGYEVTPVVALWSEPLPLAPVDPGEVANVLQLRISQLSDPVNRVTATIPGGYRGPGFQLGDLFIWGMTAHLLDVTLRVAGWERSWDRDREVPVPGRFLRD
>LR134535.1|VEJ57510.1|398637_399405_+|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA
MTTAISFQNVTKDYATSKGIVRALRGLDLEIPQGVIYGLLGPNGAGKTTALEIAVGLREATGGLARTMGLDPVRENAEVRNRISIQPQNATGFDLLTGEELLDIWSALYPNPRPAEELIRLLDMSGYIDRQLRRLSGGQRQRVNLALALIGGVNVTVLDEPSTGLDPMARADLWDALRHLKQEGMTIILSTHDMEEAEVLCDCLAIIDAGAVVAEGSPSELIADAERRHQGPDRFRGLTDVFFQAAGRSFHQQNK
>LR134535.1|VEJ57511.1|399422_400235_+|ABC-type-transport-system-involved-in-multi-copper-enzyme-maturation,-permease-component
MSTLSITRPLTAANQEIAMPTASVTRKLFKLHWLELTRNRAQFIFAMVFPLFMGGMFFLISTVMPSSTAANFGAMILPMSGYLALSGVALNLTAGPLVQYREQGTFRVLGTTPLSRTRFLLTHLFLRVVFAMALCVVLYLLGAVIGLADWAAIPALTAASLPALLLFLAIGYWLGGVMTSSQATSSVSAFLQVGFLFISGAGIPMWLLPETFQQVISWLPPALSVDPLFWAANSPFQRHDPWLTSGITIALAALVMLAAIRTFRWEVRSR
>LR134535.1|VEJ57512.1|400321_401581_-|Uncharacterised-protein
MKTWNTVLRLSAALFLVLLPLGSCTPAGNRDNSPTPPFSLNLKDAGNSYSPFITPSRKGSGWKLSASVSIDNSRSVHSTPFGIIIVLNTYYPLDTSSKNDDSQATKILCLDPTNGSLKWTRILEPASSEIGRSDTGTAQDLFKRDSSPGKPAPVVTSPNGHHLAIMVKPYLVSGSSSDMSDQRMHIVVIDTETGNATRTVEVSGLVLGQALTNDSLVVETSQHFYPAGTGTLNVFSLTEAQAEPTSFRTDRWLAGATSDSLLVSPQNLREYGHLPTTLTRISTSGEELGTVAGVTAVSDGSWVFRYQDPEAATAAIKAGSKDVLPKELFNIESGAAFDITDLDVVSAGLSTGPGFLLRRLVPGDNDEQKPFYVPVSWLPATPDSKELRTDDVAWFSEGDSKKQEGRYIMRTVRMGEKPG
>LR134535.1|VEJ57513.1|401580_403611_-|Uncharacterised-protein
MAPTPDDAVTTADPPPRFVPGLRNLRLAGLGVITAAALLAIPFWDDGVLLLSTVTPHLLVLAAIPVFWLLAVWLGFRRIIPAVIVAVGSITAAGFHCRRWWVVYEQSSIRLGLLLVMAVVSLGLGLFAVSDLLLRGIRDSMDPFPEAPDNPARFRPLPRVPVPPDTEVRRIARILSPSLALGIAVLLVHVFANPVSQVTASPPPGDLPARPTRIGTTLAWEKDVPGLLGIIAGAAGPVLFTDEGLTALNPTDGSVLWSYRRDKASYFPIPHLRSYGGPDTPDFTTSPTGRHIAFRIRSAKDLMDKPRKITDQTLVYDAVTIIIDALTGKVTGEHPSNTTWRIQLSDSALLDGDTAYNLADGQQRWTLAETQRSATRDLYSESWDYSGPAGHNSFILSYTRNGLLGLYHYDALDGVLRVAPDTDPTKISEVVSIAVDGEYSTPVVAGGWVAHFTEPIDVQDSEPNEDGETHKIIAKGIETEAVTLDSLAGLEPKSPVALGRTTGINSFVSGMTGTLAAYPDYSPDTLPIRDLNDRSDKPKVGAVFDPVTRTATQASQYPGLAAAKAGIAVTADDGSGTGAIIMQPGDGSQATTIPITPGTTTMSPEALGARSPDALPQLTTPIVAAYNSTIFMTVPGLTLVAFDPEAGVGYESHVKEKEVGYVHRHVHRLYGLTGES

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Crispr_ID: LR134535_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134535_5

433582-433679

Unclear

Consensus_repeat	Method
CTCAACCGGCTTGGGAAGAGGGGCG	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of LR134535_5

>merge|LR134535|5|433582-433679|CRISPRCasFinder
CTCAACCGGCTTGGGAAGAGGGGCGCTCGCGGCCCGTCTCAACCGGCTTGGGGGAGGGGTGCTCGCGTGCTGGCTAAACCGGCTTGGGAAGAGGGGCG

>LR134535|5|5|433582-433679|CRISPRCasFinder
CTCAACCGGCTTGGGAAGAGGGGCG	CTCGCGGCCCGTCTCAACCGGCTTGGGGGAGGGGTGCTCGCGTGCTGG
CTAAACCGGCTTGGGAAGAGGGGCG

Protein	Signature genes	Signature genes Name	Protein_function
LR134535.1\|VEJ57541.1\|441839_442586_-\|Precorrin-2-C(20)-methyltransferase	unknown	unknown	gnl\|CDD\|381172
LR134535.1\|VEJ57534.1\|433724_435956_+\|ATP-dependent-RNA-helicase-SrmB	cas3	mkCas0139_cas3_CAS-I	gnl\|CDD\|274800
LR134535.1\|VEJ57529.1\|428193_428958_-\|Methyltransferase-domain	unknown	unknown	gnl\|CDD\|369777
LR134535.1\|VEJ57538.1\|437339_438566_-\|Sirohydrochlorin-cobaltochelatase	unknown	unknown	gnl\|CDD\|225049
LR134535.1\|VEJ57543.1\|443492_444638_+\|cobalt-precorrin-6A-synthase	unknown	unknown	gnl\|CDD\|234615
LR134535.1\|VEJ57526.1\|422222_424262_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57542.1\|442780_443503_+\|Precorrin-8X-methylmutase	unknown	unknown	gnl\|CDD\|181352
LR134535.1\|VEJ57536.1\|436422_436917_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57535.1\|436039_436426_-\|helicase/secretion-neighborhood-TadE-like-protein	unknown	unknown	gnl\|CDD\|274799
LR134535.1\|VEJ57531.1\|430075_431215_+\|Type-IV-secretion-system-protein-virB11	unknown	unknown	gnl\|CDD\|200328
LR134535.1\|VEJ57532.1\|431208_432219_+\|Flp-pilus-assembly-protein-TadB	unknown	unknown	gnl\|CDD\|227300
LR134535.1\|VEJ57537.1\|436922_437147_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|379429
LR134535.1\|VEJ57530.1\|428969_430076_+\|Flp-pilus-assembly-protein,-ATPase-CpaE	unknown	unknown	gnl\|CDD\|274798
LR134535.1\|VEJ57539.1\|438565_440986_-\|Cobalt-precorrin-3B-C(17)-methyltransferase	unknown	unknown	gnl\|CDD\|381173
LR134535.1\|VEJ57527.1\|424584_427182_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57524.1\|421392_421665_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57540.1\|440982_441843_-\|Cobalt-precorrin-4-C(11)-methyltransferase	unknown	unknown	gnl\|CDD\|200107
LR134535.1\|VEJ57528.1\|427688_428138_-\|Protein-of-uncharacterised-function-(DUF1469)	unknown	unknown	gnl\|CDD\|377816
LR134535.1\|VEJ57525.1\|421782_422226_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57533.1\|432215_432827_+\|Flp-pilus-assembly-protein-TadB	unknown	unknown	gnl\|CDD\|224975

Protein	Function_ID	Function_description	E-value
LR134535.1\|VEJ57541.1\|441839_442586_-\|Precorrin-2-C(20)-methyltransferase	gnl\|CDD\|381172	cd11645, Precorrin_2_C20_MT, Precorrin-2 C20-methyltransferase, also named CobI or CbiL. Precorrin-2 C20-methyltransferase (also known as S-adenosyl-L-methionine--precorrin-2 methyltransferase) participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways in bacteria. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. Precorrin-2 C20-methyltransferase catalyzes methylation at the C-20 position of a cyclic tetrapyrrole ring of precorrin-2 using S-adenosylmethionine as a methyl group source to produce precorrin-3A. In the anaerobic pathway, cobalt is inserted into precorrin-2 by CbiK to generate cobalt-precorrin-2, which is the substrate for CbiL, a C20 methyltransferase. In Clostridium difficile, CbiK and CbiL are fused into a bifunctional enzyme. In the aerobic pathway, the precorrin-2 C20-methyltransferase is named CobI. This family includes CbiL and CobI precorrin-2 C20-methyltransferases, both as stand-alone enzymes and when CbiL forms part of a bifunctional enzyme.	6.83244e-69
LR134535.1\|VEJ57534.1\|433724_435956_+\|ATP-dependent-RNA-helicase-SrmB	gnl\|CDD\|274800	TIGR03817, DECH_helic, helicase/secretion neighborhood putative DEAH-box helicase. A conserved gene neighborhood widely spread in the Actinobacteria contains this uncharacterized DEAH-box family helicase encoded convergently towards an operon of genes for protein homologous to type II secretion and pilus formation proteins. The context suggests that this helicase may play a role in conjugal transfer of DNA.	0
LR134535.1\|VEJ57529.1\|428193_428958_-\|Methyltransferase-domain	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	5.19232e-11
LR134535.1\|VEJ57538.1\|437339_438566_-\|Sirohydrochlorin-cobaltochelatase	gnl\|CDD\|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	5.19925e-30
LR134535.1\|VEJ57543.1\|443492_444638_+\|cobalt-precorrin-6A-synthase	gnl\|CDD\|234615	PRK00075, cbiD, cobalt-precorrin-6A synthase; Reviewed.	2.28347e-129
LR134535.1\|VEJ57542.1\|442780_443503_+\|Precorrin-8X-methylmutase	gnl\|CDD\|181352	PRK08285, cobH, precorrin-8X methylmutase; Reviewed.	1.86987e-103
LR134535.1\|VEJ57535.1\|436039_436426_-\|helicase/secretion-neighborhood-TadE-like-protein	gnl\|CDD\|274799	TIGR03816, tadE_like_DECH, helicase/secretion neighborhood TadE-like protein. Members of this small, highly hydrophobic protein family occur in a pilus/secretion-like region that usually is next to an uncharacterized DEAH-box helicase, in Actinobacteria. Members show sequence similarity to the TadE-like family described by pfam07811. The function is unknown. [Unknown function, General].	1.0235e-09
LR134535.1\|VEJ57531.1\|430075_431215_+\|Type-IV-secretion-system-protein-virB11	gnl\|CDD\|200328	TIGR03819, heli_sec_ATPase, helicase/secretion neighborhood ATPase. Members of this protein family comprise a distinct clade of putative ATPase associated with an integral membrane complex likely to act in pilus formation, secretion, or conjugal transfer. The association of most members with a nearby gene for a DEAH-box helicase suggests a role in conjugal transfer.	1.50022e-149
LR134535.1\|VEJ57532.1\|431208_432219_+\|Flp-pilus-assembly-protein-TadB	gnl\|CDD\|227300	COG4965, TadB, Flp pilus assembly protein TadB [Intracellular trafficking and secretion].	4.21976e-18
LR134535.1\|VEJ57537.1\|436922_437147_-\|Uncharacterised-protein	gnl\|CDD\|379429	pfam14029, DUF4244, Protein of unknown function (DUF4244). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 66 and 95 amino acids in length. There is a conserved EYA sequence motif.	1.23832e-05
LR134535.1\|VEJ57530.1\|428969_430076_+\|Flp-pilus-assembly-protein,-ATPase-CpaE	gnl\|CDD\|274798	TIGR03815, CpaE_hom_Actino, helicase/secretion neighborhood CpaE-like protein. Members of this protein family belong to the MinD/ParA family of P-loop NTPases, and in particular show homology to the CpaE family of pilus assembly proteins (see ). Nearly all members are found, not only in a gene context consistent with pilus biogenesis or a pilus-like secretion apparatus, but also near a DEAD/DEAH-box helicase, suggesting an involvement in DNA transfer activity. The model describes a clade restricted to the Actinobacteria.	3.02308e-42
LR134535.1\|VEJ57539.1\|438565_440986_-\|Cobalt-precorrin-3B-C(17)-methyltransferase	gnl\|CDD\|381173	cd11646, Precorrin_3B_C17_MT, Precorrin-3B C(17)-methyltransferase (also named CobJ or CbiH). Precorrin-3B C(17)-methyltransferase participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. This model includes CobJ of the aerobic pathway and CbiH of the anaerobic pathway, both as stand-alone enzymes and when CobJ or CbiH form part of bifunctional enzymes, such as in Mycobacterium tuberculosis CobIJ where CobJ fuses with a precorrin-2 C(20)-methyltransferase domain, or Bacillus megaterium CbiH60, where CbiH is fused to a nitrite and sulfite reductase-like domain. In the aerobic pathway, once CobG has generated precorrin-3b, CobJ catalyzes the methylation of precorrin-3b at C-17 to form precorrin-4 (the extruded methylated C-20 fragment is left attached as an acyl group at C-1). In the corresponding anaerobic pathway, CbiH carries out this ring contraction, using cobalt-precorrin-3b as a substrate to generate a tetramethylated delta-lactone.	5.01759e-108
LR134535.1\|VEJ57540.1\|440982_441843_-\|Cobalt-precorrin-4-C(11)-methyltransferase	gnl\|CDD\|200107	TIGR01465, Precorrin-4_C11-methyltransferase, precorrin-4 C11-methyltransferase. This model represents precorrin-4 C11-methyltransferase, one of two methyltransferases commonly referred to as precorrin-3 methylase (the other is precorrin-3B C17-methyltransferase, EC 2.1.1.131). This enzyme participates in the pathway toward the biosynthesis of cobalamin and related products. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	2.93668e-121
LR134535.1\|VEJ57528.1\|427688_428138_-\|Protein-of-uncharacterised-function-(DUF1469)	gnl\|CDD\|377816	pfam07332, Phage_holin_3_6, Putative Actinobacterial Holin-X, holin superfamily III. Phage_holin_3_6 is a family of small hydrophobic proteins with two or three transmembrane domains of the Hol-X family. Holin proteins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.	1.23194e-06
LR134535.1\|VEJ57533.1\|432215_432827_+\|Flp-pilus-assembly-protein-TadB	gnl\|CDD\|224975	COG2064, TadC, Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion].	4.91946e-13

>LR134535.1|VEJ57533.1|432215_432827_+|Flp-pilus-assembly-protein-TadB
MSTAVLIGFLVAAAVLAWWAPPPLSRLEPRSSPLPGWVGKVWGWAAKRWSGRRKVNRAVVRELPETLDLLAVCLEAGAPMTNAIATVAAVSQPATAAILHGIDAQLQVGRDPQDAWGSLADHPDWGPPARDAARSARSGTSLVECLRVHADEARRRRREQETKRARSVGVKSVQPLALCFLPAFVLIGVVPLVASLLGTFTGR
>LR134535.1|VEJ57532.1|431208_432219_+|Flp-pilus-assembly-protein-TadB
MLICVVFFALAAALIAGKEQNLERLGLPARRRPGRGSAAVVRKTSRPVPSNFPLRRRGMVPGDAGIPVPRPGDGESAVVDGARVGALEKLEESQARGGRSGHGKAVASHRARMRRNNLLLMGGAGLVAVAVVFGLRAAGWTLVVVIAAATAAWVLRRAAAERARRNRADETTRVTVGLAMLLRSGQIPTAALAETATDCDALAPVAAVARLGGDVPAALQEVAQTPGREGLARVAGAWRVAERTGAPVASVLLQVAEGLRAERELAGVVEAELAMARGSARIMAFLPLGALLLGSCVGADPLGFLLENPLGLVLALAGVGLAAAGVVWTEKLAVRQ
>LR134535.1|VEJ57531.1|430075_431215_+|Type-IV-secretion-system-protein-virB11
MLDELQARLGRLGRPHTAADVATAMRGMGLVVTDTALRQAMDQLRRNSVGAGPLEELLHEPGVSDVLVNGPDAVFVDRGAGLEAADVRFVHDEAVRRLAIRLAATAGRRLDDAQPFVDGRLPGGVRLHAVLAPLASPGTCISLRVPASRTLTLEELHTAGSLTDEALELCRRVIARKVPFLISGGTGTGKTTLLAALLAEVPATERIVVVEDARELTPRHPHCVRMEGRPPNNEGKGAITLTTLVRQALRMRPDRVVLGEVRGAELTDLLSALNTGHEGGCGTVHANSVADVPARLEALAALGGLGREACHAQLAAALRLVLHLRRGPDGKRWLAEVGAFRRGADGLVGIVPAMTFTGGATTWGPGAGLVRDWLEWSRC
>LR134535.1|VEJ57530.1|428969_430076_+|Flp-pilus-assembly-protein,-ATPase-CpaE
MFFSYSKQVIHIFGQKWRFGSAGSQSENVNTSEITGPLLATREAALADSVLATTLALGIDLDVVPDREELRRRWRTASLRLVGTDMASRAATLGAVPGVWVVGFDSEELLQASAELGAPALLLPGESQRLAEVLSSELPGQDAAQILALIGASGGLGVSCLTVALSTRAADTGLRSAAVELAGCGGGLDLLFGAETQVGMTWEELRHAVGEIGDLTPHLVSAERVSVLALGRPHGDSPDEAALSAVLRSLERSHDMVVVDLGDGARLAELGRRAVPLLMVGADVRSVAAARMRARRIDLTGALLVVRVGKGRGLPPEAVSDALGLPLAGVVRDDPRVPRLAAQGASVGSRPAARLRRDSTRLLKEVRL
>LR134535.1|VEJ57529.1|428193_428958_-|Methyltransferase-domain
MTTTDPLPPEALTWLAVWPGVRGLTFGGSLLPQRLEEAGHTVFAMADTDRDMRRLLALQGITPFWARPEAIPIDPCQFDVVFSHQSFHLFDPGQALSEIARVLRPGGCFSASYIIRDDSVPWVRRLTALLRHYDPMAMRGDYGHASLAAVDDSKYFPEVEHRAFRIWQTVSLDDLQQLVANQPLSRRLSEVQRKRLADEIKTLFEQSVRPGENLRLPFQLLAWRAWVNHDELTEPVSMPESGIEIDMQVATPLR
>LR134535.1|VEJ57528.1|427688_428138_-|Protein-of-uncharacterised-function-(DUF1469)
MARPTPFQLLRDGLMDFVARETELAKAELVPAAKHAGIGSAFVAAAVTFLLHSMWMLVIVLALALSWLLSLTGLKTVGCLTLGFLAAALLSIGIAVLLIFMARGRFQKVKAPTATIEEARATFVALTDAAIGQSTEVVVKEEPSLPEVG
>LR134535.1|VEJ57527.1|424584_427182_+|Uncharacterised-protein
MLGAERIRGIVAGLEMKYARTRWRSDNLRGDHDRSVHEPPRSPVLEPGRLEPVPGIERGPLQLIDARTGIVPFADRDELRALIDWACAPQAGNGRDLALAVVTGAGGSGRTRLAVELCSALGRNGWGTGFVSDPADLGDAELTWLAEMESHLLVVLDHAEECRTGNLARLLVHLRDRAAPTRVVLVARNAGQWLTDLLEGLEHRGEALGDPLGIALPHEPGDAAGIVARAAGAFARHMRRPEPGDVQIPRDQPWTTLDLVLLGWLLAARDNAADLPGSRDELYDEILRREISAWQAEAIRRGLGELPEATWRTAAATLSLLRPVTPEEVRDVLSRLPEASAVPDTEGYARLLFEMLSRPAGGCALRPEPIAEHLIIATFVDGEGCEDPEKLLDQVLPEPPGTPGPGDTGCSTPGTGQTDARDARDERVCDAITRCTSRGDAAAVRLARFVLRHRPHLWVAALDVAQRQGGPFVTALEDALKGGADLPAITILAAIWPGDPVLRGVAVAALARVLETSREPMNLLGLSTHLADAGDRVGALEMARKAVRTHRESADEDSTDQGLILPLANLASRLWDVGDHAGALNVEREVVRIHRRLTGEFRVFFGSRLVVSLAGCSARLVEAGNSAQAVEVLREAVGIHRETIEVYRGLSAELRRGFGPFLAMPLSALATQLAELGDFPEALVAAREVVDLQREVVEETATRGDDAPACATDTPPRAEADRDSRDVLPDKESGHIDHGEFIYIEVLLTLAAVSSAEQAHDIAGNPGKAHEAVRGFIGEANVSAILCALRLRPELADHVPCGRFAAALHACLTDAPGEAERHLSGIGDHVAPDDLDIFRRCAHTLGREPDYTDALAPVAEWLRTG
>LR134535.1|VEJ57526.1|422222_424262_-|Uncharacterised-protein
MALPCSIMKCMSQTSDDIVDADANGIPIAANRRVLVLRALRIGGLVAVLPGMILAVVWWNNFPLPPDLLRSFLQLLLPLPALWVASGLVRKVCHWFEEEFAHTIWRRARKFFASLVAVYTIAVTGWHVHRWWHFHTGFSFSIIVLLTLAALTVALGLATTVDLWLRGIRDQRDILSGAPDDPVRFRPFRPAANDEDDSDSPRRRSRRYWGRRFIALLAPALALTLTLLLVHNAPNPVVQTTTHAPDGPLPTRPTRLGARIAWEKDVPGLLDLKSGVTGPLILTPEGLTAVNPTDGSTLWSYHRPRARYSRFWNWGQQNMFGASPRNSSYLLTNPNGHYVALRIVIPPTLKQGDKIIHEGVLTIIIDTTTGQVTSERLTEEYSTFQLTDTAFFDGRTAYNLSDGQARWTLKAEDMEEGVSFAGPTGHNSFVINMKINPNSRHHNIYDLTLASDKDPSRKATASNFPATDKISNDRPVSVDGWTVQYAEKVDDPDQDAARKMQAVSFDSLAGLEDTPAVDLGKTFGPNTVASHASGTLALHPDTSSSDPAAQQVGTVFDPATRTVTSASECAGPVAVRLGITRVTDGGSVSRALAIQPCDGSDGLTLPVAPGPFKPPTKTEESAPRQLSERSQAEQIATMVNAPGATLIVFNPEGEAKANGTSEVDRKYPYHLYALTGDAS
>LR134535.1|VEJ57525.1|421782_422226_-|Uncharacterised-protein
MKSLTPLTRFIVVALLLTFSLTACSREAGNRFTSLTETNDVSDLVSAPSTADPGWTVDLIKKFYANLTLPTASGPILLFRTSRPAGSGALNLFPLGDTRAEPTTLRADQWLAGTTHDSLLLTPNELTDLQQDYPSPGSAPPERPWEQ
>LR134535.1|VEJ57524.1|421392_421665_-|Uncharacterised-protein
MWKPEQSSIPPVSGSPQKPFPTGPGIRLYTNATANKDWADDIEGRTTYSWFPATPGSTTLRTDDMPWITDHVIADDKQTLSRSVIHMEKS
>LR134535.1|VEJ57534.1|433724_435956_+|ATP-dependent-RNA-helicase-SrmB
MNWEWVTGAEEAVVVRRRPVSPGAWADWPGWLDAELVDGFRAAGIDRPWRHQVEFAELARAGRHAAICTPTGSGKSLAYLMPVLAALREPRAGRGRGFALRRPTALYLAPTKALAHDQARAAGALAPGPVRIGALDGDSDEAERRFAREHANLVLTNPDMLHFSVLPNHRRWSALLGGLRYVVIDEAHRYQGVFGAHVAQVLRRLRRLAAAHGAEPTILLSSATAPNAADFGGALIGEERVEVVADSTAPVAARTVVLWQPSVSLNRDTSRLLAGLVDDATQTLAFVASRAGAELTSLEAAELAAEPGRIASYRGGYLAMERRDLEAALQTGEILGLATTNALELGIDVSGIDAVLVSGFPGKLSAFWQQAGRAGRAGREALVVLLARENPLDAYLLQHPELIFDAPVEAAICHPQNPHVLGPHLAAAAQEQPLTAADERWFGPTALPLAAHLAAGKVLRDRSGTWYWTRPDRAVDHINLRSTTPRPVEIIERSTGQVIGVVDPAAADRTVHRGAVYLHQGRSFVVTELDVEERSAMVVAAHNPWYTQAKSAQDIAVLREQRSRPLGSTTLHFGDVRLSWQVTGYLRRDETTHEVLDSTPLDCPEHTLTTQAVWWSVPEALERELGWGSLRLGAAAHAAEHTSIGLLPAFAPCDRWDIGGVSTARHPDTGLATVFVHDGLPGGAGFAARAHEVAEQWLAATLERLRTCRCESGCPACVVSPKCGNANQVLDKTAATELLRRIL
>LR134535.1|VEJ57535.1|436039_436426_-|helicase/secretion-neighborhood-TadE-like-protein
MSVTGGLGRSRVHNERGVGTVLVAGICLGLVLVAATAALITGWLARAEKAQDAADLTALAAAAVEADGGDACAEASKVASENGGRLTGCEVRGQRPRFVVEVTVTLPLLEGRGFNPADVERSATAGTV
>LR134535.1|VEJ57536.1|436422_436917_-|Uncharacterised-protein
MRGADVSAPRLLVEGPGARGEETSTAVAGHPVSPAPRRRRAGRVGWFGRRRARRGQRGMVTVEFAIGLVTLVTLVSALVGLVLLGVAQSGIQTVSSELAKYLSRGDDALAEKTKEKAPERARIEIERAEAGVRVTTRMEVPILGLGAIPLEATAWAHWEPGVGP
>LR134535.1|VEJ57537.1|436922_437147_-|Uncharacterised-protein
MSESTKSIARVEKKKSLSRRFAERGLTTVEYAIGLLGAAAAAMLLIRVFHDNSLFDTIMKWVTDLFTNVAQYDS
>LR134535.1|VEJ57538.1|437339_438566_-|Sirohydrochlorin-cobaltochelatase
MLKELTNVPLVIAAHGTRDPEGVAVCRALAERVQAKLPDTKLTMGFVELTEPSIPEAVAEALEGLEPKGETDAVVVPLMLATGGHVRIDIPEAIDEGRGAAKVAYSAALLGSPLLDSAVRNRVVEALGEWRPQDTACVLVGRGSPVTESNAERYRLARTLMEEAGLRSIHPAFIQVSRPSVPEALNHAKATGAKQIVVAPHFLFPGKLRTWNLDQVAAWRENNPDVEVRVAEVIGDCDELAQLVVDRYLAELDAEGFGEGAPGFMSNLVLKDRDVLVVGGGAVAARRIPRLLDAGAKVRVVAPNLGIAVGRLAASGAITAEQRTARAEDVGEAWYVLAASNDPNVNAMIAAEAERRHTFCCRADDALGGTATTPTTASAGGLTVAVIGDRNPRRSVRVRDELLQVLQD
>LR134535.1|VEJ57539.1|438565_440986_-|Cobalt-precorrin-3B-C(17)-methyltransferase
MITVHGHLGAPSEELRRAVAAASVVVGGRRHLDELAVPEDKRIVLGGLTPAVEKIRQLPEDTDVVILASGDPLWFGVVRKLRSIGLRPKVVTRASSVAEAFARIGLPWDDAITVSAHGRPIDAAITAARRYAKVAVMTDPREPLSQLTDPLAGLDRTFVLAERLGEDDERVRIMTGEQLAAVEDVRNPNVVLVLERHPDAEWDETAVDTTAPRRVAVPEVAVERLTANALAELTVGQVFSSEAARARAAQIDELLGGTRIYDGPATEGLRQAFDECDLVVSHLAIGATTRILAPLLDSKKTDPGVVVIDQGGHFVVPLLGGHVGGANELAEKLSEALGATAVLTTATDSLGVPALDTLGWAHSGDVAGVTGAMLDGRSVRLVRDQPWPMPPLPANVTEDAASPVAEILVTDRDASQLPAAELPRVVLHPRSLVVGMGCNRGTSEKILRAHLEATLASAGLTIHSVAALTSVDAKAREGGLIRLAKHLGVPFVCYEAAELAGIEVPTPSEVVASEVGTPSVSEASVIRRGAELIVPKTKCPDATCAIGRVPARGELRVVGLGPGHRDLLTPMAKQAIETARYVVGYIPYVRQIRDLVNPHAETHATKMGTEEQRTAFAIQKAREGHPVAFVCSGDPAIYAMASPTLEIGTEGIDVKIIPGVTAELAASALLGAPLGHDHVTISLSDLHTSWEDIERRLQAAAEGDFVTVLYNPRSRKRIAHLPRALEILGAHRPADVPVMAVYEAFRPKQHIRWAPIGEFNPEWVDMHTIVIVGSSTTKPVATGVGETAIVTPRDYQWMGKIQGGNC
>LR134535.1|VEJ57540.1|440982_441843_-|Cobalt-precorrin-4-C(11)-methyltransferase
MSGLRLDPKGLVVFVGAGPGADDLITVRGARVIAEADIIIWASSLVHPGIVADHKPGAEVIDSASIPLEDLVPLYTRARDEKLLVARVHTGDPDIYGATAEQRDLCAQIGIPTETIPGISAFSATAARVDSELTLPEVAQSMILTRLEGGRTPMPEKENIRSFAAHGTTMSIYLSAARNKQLEAALLEGGYPPETPCIIGYRVTWPDEAIWRVQLKDLSATMKEHKLWKHTIVLVGPALATDRAAKRSHLYHPGFRHEYRAADKAAEADLREHGATTYNLENGDNT
>LR134535.1|VEJ57541.1|441839_442586_-|Precorrin-2-C(20)-methyltransferase
MSVDRTLSGVGVGPGDPDHVTVKALRTLEAADVILVPSTEARAGGIGRAEEIVCAHLPAKVGAVRRIPFSMAERRGIGQRRADAWEASATAAVEAFEAGAKRVAFATVGDASVFSTFSYLCDLVSRRVEVKVEVIPGITAMQAIAAASRTPLVEGQEILSLVPWTVGPETLARVCEVSDTVVIYKGGREMTELRAVLDAQGRLGEAILGTDLGLPSEHLVPLSEVTDRAPYFSTVLAAPKRSTTGGRI
>LR134535.1|VEJ57542.1|442780_443503_+|Precorrin-8X-methylmutase
MSRSGRAARPGWPAAGGDCLSLGGVTNDYIKTGSPIYARSFEIIREESNLARFPEDVEPVVVRMIHAAADPAIADLIAFTPGVAAAALKALEAGAPILCDSSMVATGIIRSRLPEHTRIVCHIKDPRLPAIAEAKGCTKTAAAVDLWQEDGLLDGAVVAIGNAPTALFRVLEVMRETGARPAAIVGIPVGFVGAAESKDALVADDSGVEYITVLGRRGGSAMAVAAVNAMASRAETTNDR
>LR134535.1|VEJ57543.1|443492_444638_+|cobalt-precorrin-6A-synthase
MTADGDPALAAEGREALRPRGRKAQLESSQLRPGWTTGACACAAATSAFVALETGEFPDPVGIALPGGREAAFALTQWRLRPGLAMAAVTKDAGDDPDVTHGAVVRVMVEPGEPGGGVRFAGGEGVGTVTLPGLPLPVGEPAINPKPREYITANITAAAERLGVAPDVRVTVSIDDGARIAEKTWNSRIGVLGGLSVLGTTGVVVPYSCSAWIASIHRGIDVAIATGATHAAACTGSTSERVAEELYPGIELLDMGDFAGAVLKYLRKHPLPRLAIVGGVAKLSKLAAGYLDLHSHRTRIQPGHLRQLVEGAGASPELADAIGEVATVAHAVTLASEAGIDLPQLIADSARDEALAVLGGAPVEVEIVVIDRAGKILARAH

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Crispr_ID: LR134535_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134535_6

668485-670559

Unclear

Consensus_repeat	Method
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CRT
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	PILER-CR
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CRISPRCasFinder

28 spacers

cas2,cas1,cas8u1,cas3,csb2gr5,csb1gr7

The CRISPR arrays of LR134535_6

>merge|LR134535|6|668485-670559|CRT,PILER-CR,CRISPRCasFinder
AAGTATGTAGAACCTGATCTTTGAGATCAGGAAAATCGCGACCCATAGTTTCGTGCCGTACCCCGCTTATTTGTCGCATTGGAGCCTGACCTTTGAGGTCAGGAAAAGGGGATGGTACTGCCACAATGGGAACACCAATCGAAGCGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGGCCAAGGTCGACTCGGTGTTCCGCGGAATCGACGGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGGTGTTCACAAATGGGAAGAACAACTACCCCAGAATGGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGGCGGCAGCGGATGCGGCTGCACCGACCGCAGAAGCGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGCCCGGTGCCGGAGTACCGGGCGGGCTCCCAGCCGAGGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGCCGGCGATCTTCCCACCCAGGCCCTTGATGCCGGAGGAGTCGCAATGGAACCTGACCTTTGAGGTCAGGAAAAGGAGGCGTTTTGCCTTCGCGCCGGCTGCGGCGAGGTCGTCGCAATGGAGCCTGACCTTTGGGGTCAGGAAAAGCTTCAGCGCGTTTTTGCCGTTGTAGTAGTTACGGCGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGCATCAGGCCACGACCAAGGTTTTGTTGACCACACACTCGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGCCGTCTCGGCCGTCGAGGCCTTCGCCTTCGGGGTGCCGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGTCCCCAGTCCGTCTCCACAAGGACGTATGCGCATGCCGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGAATGTTCCCGGCTTGGTCGTCTTGGTTGGGGTCGAGGAGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGTAAAACTCGGCCTTACGCGCACCAACGGAAAGCCTTGAGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGAGAGACGGCAGAATCCCTGCGGCGAGTGGGAGTATGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGTACAGGCCGGAGAGGTCTTTGGCGTAGGCGCGCCGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGGCACGATCGCTCCGGGCACTTCGGTGGCGATAGCCCCGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGGCCCGGGCGGCAGAACTGATCGGCACCACCGCCAAGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGAACTCGCCGACTCAATCGGCGAAACCTGGGACAAGATGTCGCAATGGAGCTTGACCTTTGAGGTCAGGAAAAGTATCAGGCTCTCAATCCCGATAAGACGGTTGCGTCGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGTCAGAACTCAGGCAGTCGGATCCGGCCCCGAACAGGAGGTCGCAATGTAGCCTGACCTTTGAGGTCAGGAAAAGCTTCACCGCCTCCAGGGCGGCGTTACGGCGGTTCGTGTCGCAATGGAGCCTGACCTTTGGGGTCAGGAAAAGTCCGCCCGCACCGCCACCGGAGAACGCTCCTCCGGCCGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGCGGCGGAGATCAACGCGGCCGCGGTCTGCTGCCAGCCGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGCCACCAGCACGGGCAGCGGAGCCCCCGCCGAGACCACGGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGCATCTCGAAAAGGGTGGGTGTGCTGCCCACCCCGATGGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGGTGGGAGGAACCCATCCGGGTTGTCGCAGCGAAGGTGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAGGAGCACACCCCGCATAACGACTTTTCAAATTCGTGGTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG

>LR134535|6|3|668485-670559|CRT
AAGTATGTAGAACCTGATCTTTGAGATCAGGAAAAT	CGCGACCCATAGTTTCGTGCCGTACCCCGCTTATTT
GTCGCATTGGAGCCTGACCTTTGAGGTCAGGAAAAG	GGGATGGTACTGCCACAATGGGAACACCAATCGAAGC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCCAAGGTCGACTCGGTGTTCCGCGGAATCGACGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GTGTTCACAAATGGGAAGAACAACTACCCCAGAATGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCGGCAGCGGATGCGGCTGCACCGACCGCAGAAGCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCCGGTGCCGGAGTACCGGGCGGGCTCCCAGCCGAGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCGGCGATCTTCCCACCCAGGCCCTTGATGCCGGAGGA
GTCGCAATGGAACCTGACCTTTGAGGTCAGGAAAAG	GAGGCGTTTTGCCTTCGCGCCGGCTGCGGCGAGGTC
GTCGCAATGGAGCCTGACCTTTGGGGTCAGGAAAAG	CTTCAGCGCGTTTTTGCCGTTGTAGTAGTTACGGCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CATCAGGCCACGACCAAGGTTTTGTTGACCACACACTC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCGTCTCGGCCGTCGAGGCCTTCGCCTTCGGGGTGCCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TCCCCAGTCCGTCTCCACAAGGACGTATGCGCATGCC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	AATGTTCCCGGCTTGGTCGTCTTGGTTGGGGTCGAGGAG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TAAAACTCGGCCTTACGCGCACCAACGGAAAGCCTTGAG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	AGAGACGGCAGAATCCCTGCGGCGAGTGGGAGTATG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TACAGGCCGGAGAGGTCTTTGGCGTAGGCGCGCCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCACGATCGCTCCGGGCACTTCGGTGGCGATAGCCCC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCCCGGGCGGCAGAACTGATCGGCACCACCGCCAA
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	AACTCGCCGACTCAATCGGCGAAACCTGGGACAAGAT
GTCGCAATGGAGCTTGACCTTTGAGGTCAGGAAAAG	TATCAGGCTCTCAATCCCGATAAGACGGTTGCGTC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TCAGAACTCAGGCAGTCGGATCCGGCCCCGAACAGGAG
GTCGCAATGTAGCCTGACCTTTGAGGTCAGGAAAAG	CTTCACCGCCTCCAGGGCGGCGTTACGGCGGTTCGT
GTCGCAATGGAGCCTGACCTTTGGGGTCAGGAAAAG	TCCGCCCGCACCGCCACCGGAGAACGCTCCTCCGGCCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CGGCGGAGATCAACGCGGCCGCGGTCTGCTGCCAGCC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCACCAGCACGGGCAGCGGAGCCCCCGCCGAGACCACGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CATCTCGAAAAGGGTGGGTGTGCTGCCCACCCCGATGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GTGGGAGGAACCCATCCGGGTTGTCGCAGCGAAGGT
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GAGCACACCCCGCATAACGACTTTTCAAATTCGTG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG

>LR134535|6|3|668557-670559|PILER-CR
GTCGCATTGGAGCCTGACCTTTGAGGTCAGGAAAAG	GGGATGGTACTGCCACAATGGGAACACCAATCGAAGC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCCAAGGTCGACTCGGTGTTCCGCGGAATCGACGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GTGTTCACAAATGGGAAGAACAACTACCCCAGAATGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCGGCAGCGGATGCGGCTGCACCGACCGCAGAAGCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCCGGTGCCGGAGTACCGGGCGGGCTCCCAGCCGAGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCGGCGATCTTCCCACCCAGGCCCTTGATGCCGGAGGA
GTCGCAATGGAACCTGACCTTTGAGGTCAGGAAAAG	GAGGCGTTTTGCCTTCGCGCCGGCTGCGGCGAGGTC
GTCGCAATGGAGCCTGACCTTTGGGGTCAGGAAAAG	CTTCAGCGCGTTTTTGCCGTTGTAGTAGTTACGGCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CATCAGGCCACGACCAAGGTTTTGTTGACCACACACTC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCGTCTCGGCCGTCGAGGCCTTCGCCTTCGGGGTGCCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TCCCCAGTCCGTCTCCACAAGGACGTATGCGCATGCC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	AATGTTCCCGGCTTGGTCGTCTTGGTTGGGGTCGAGGAG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TAAAACTCGGCCTTACGCGCACCAACGGAAAGCCTTGAG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	AGAGACGGCAGAATCCCTGCGGCGAGTGGGAGTATG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TACAGGCCGGAGAGGTCTTTGGCGTAGGCGCGCCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCACGATCGCTCCGGGCACTTCGGTGGCGATAGCCCC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCCCGGGCGGCAGAACTGATCGGCACCACCGCCAA
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	AACTCGCCGACTCAATCGGCGAAACCTGGGACAAGAT
GTCGCAATGGAGCTTGACCTTTGAGGTCAGGAAAAG	TATCAGGCTCTCAATCCCGATAAGACGGTTGCGTC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TCAGAACTCAGGCAGTCGGATCCGGCCCCGAACAGGAG
GTCGCAATGTAGCCTGACCTTTGAGGTCAGGAAAAG	CTTCACCGCCTCCAGGGCGGCGTTACGGCGGTTCGT
GTCGCAATGGAGCCTGACCTTTGGGGTCAGGAAAAG	TCCGCCCGCACCGCCACCGGAGAACGCTCCTCCGGCCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CGGCGGAGATCAACGCGGCCGCGGTCTGCTGCCAGCC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCACCAGCACGGGCAGCGGAGCCCCCGCCGAGACCACGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CATCTCGAAAAGGGTGGGTGTGCTGCCCACCCCGATGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GTGGGAGGAACCCATCCGGGTTGTCGCAGCGAAGGT
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GAGCACACCCCGCATAACGACTTTTCAAATTCGTG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG

>LR134535|6|6|668557-670559|CRISPRCasFinder
GTCGCATTGGAGCCTGACCTTTGAGGTCAGGAAAAG	GGGATGGTACTGCCACAATGGGAACACCAATCGAAGC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCCAAGGTCGACTCGGTGTTCCGCGGAATCGACGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GTGTTCACAAATGGGAAGAACAACTACCCCAGAATGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCGGCAGCGGATGCGGCTGCACCGACCGCAGAAGCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCCGGTGCCGGAGTACCGGGCGGGCTCCCAGCCGAGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCGGCGATCTTCCCACCCAGGCCCTTGATGCCGGAGGA
GTCGCAATGGAACCTGACCTTTGAGGTCAGGAAAAG	GAGGCGTTTTGCCTTCGCGCCGGCTGCGGCGAGGTC
GTCGCAATGGAGCCTGACCTTTGGGGTCAGGAAAAG	CTTCAGCGCGTTTTTGCCGTTGTAGTAGTTACGGCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CATCAGGCCACGACCAAGGTTTTGTTGACCACACACTC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCGTCTCGGCCGTCGAGGCCTTCGCCTTCGGGGTGCCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TCCCCAGTCCGTCTCCACAAGGACGTATGCGCATGCC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	AATGTTCCCGGCTTGGTCGTCTTGGTTGGGGTCGAGGAG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TAAAACTCGGCCTTACGCGCACCAACGGAAAGCCTTGAG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	AGAGACGGCAGAATCCCTGCGGCGAGTGGGAGTATG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TACAGGCCGGAGAGGTCTTTGGCGTAGGCGCGCCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCACGATCGCTCCGGGCACTTCGGTGGCGATAGCCCC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GCCCGGGCGGCAGAACTGATCGGCACCACCGCCAA
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	AACTCGCCGACTCAATCGGCGAAACCTGGGACAAGAT
GTCGCAATGGAGCTTGACCTTTGAGGTCAGGAAAAG	TATCAGGCTCTCAATCCCGATAAGACGGTTGCGTC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	TCAGAACTCAGGCAGTCGGATCCGGCCCCGAACAGGAG
GTCGCAATGTAGCCTGACCTTTGAGGTCAGGAAAAG	CTTCACCGCCTCCAGGGCGGCGTTACGGCGGTTCGT
GTCGCAATGGAGCCTGACCTTTGGGGTCAGGAAAAG	TCCGCCCGCACCGCCACCGGAGAACGCTCCTCCGGCCG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CGGCGGAGATCAACGCGGCCGCGGTCTGCTGCCAGCC
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CCACCAGCACGGGCAGCGGAGCCCCCGCCGAGACCACGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	CATCTCGAAAAGGGTGGGTGTGCTGCCCACCCCGATGG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GTGGGAGGAACCCATCCGGGTTGTCGCAGCGAAGGT
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG	GAGCACACCCCGCATAACGACTTTTCAAATTCGTG
GTCGCAATGGAGCCTGACCTTTGAGGTCAGGAAAAG

Protein	Signature genes	Signature genes Name	Protein_function
LR134535.1\|VEJ57748.1\|667090_667948_-\|Sulfate-starvation-induced-protein-7	unknown	unknown	gnl\|CDD\|270248
LR134535.1\|VEJ57751.1\|670901_671024_-\|CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
LR134535.1\|VEJ57756.1\|677969_679115_-\|CRISPR-associated-protein-GSU0053/csb1,-Dpsyc-system	csb1gr7	pfam09617_csb1gr7_CAS-I-U	gnl\|CDD\|378223
LR134535.1\|VEJ57759.1\|682638_683568_-\|Glutamyl-endopeptidase-precursor	unknown	unknown	gnl\|CDD\|226119
LR134535.1\|VEJ57742.1\|662060_662756_+\|Staphylococcal-respiratory-response-protein-A	unknown	unknown	gnl\|CDD\|223816
LR134535.1\|VEJ57758.1\|679829_682622_+\|Calcium-transporting-ATPase	unknown	unknown	gnl\|CDD\|319781
LR134535.1\|VEJ57750.1\|670733_670850_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57747.1\|666223_667087_-\|Arginine-transport-system-permease-protein-ArtQ	unknown	unknown	gnl\|CDD\|223836
LR134535.1\|VEJ57753.1\|672693_673680_-\|Uncharacterised-protein	cas8u1	mkCas0114_cas8u1_CAS-I-U	unknown
LR134535.1\|VEJ57745.1\|664668_664863_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57752.1\|671020_672697_-\|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187766
LR134535.1\|VEJ57755.1\|676540_677968_-\|CRISPR-associated-protein-GSU0054/csb2,-Dpsyc-system	csb2gr5	cls000315_csb2gr5_CAS-I-U	gnl\|CDD\|274005
LR134535.1\|VEJ57757.1\|679287_679743_-\|homoprotocatechuate-degradation-operon-regulator,-HpaR	unknown	unknown	gnl\|CDD\|197670
LR134535.1\|VEJ57741.1\|661491_662064_+\|Protein-of-uncharacterised-function-(DUF3060)	unknown	unknown	gnl\|CDD\|371435
LR134535.1\|VEJ57739.1\|659465_660515_-\|Lipoate-protein-ligase-LplJ	unknown	unknown	gnl\|CDD\|223173
LR134535.1\|VEJ57740.1\|660675_661350_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57743.1\|662752_663622_+\|Sensor-histidine-kinase-YycG	unknown	unknown	gnl\|CDD\|223715
LR134535.1\|VEJ57744.1\|663686_664139_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ57754.1\|673676_676544_-\|helicase-Cas3	cas3	cd09696_cas3_CAS-I-U	gnl\|CDD\|187827
LR134535.1\|VEJ57746.1\|665453_666224_-\|Arginine-transport-ATP-binding-protein-ArtM	unknown	unknown	gnl\|CDD\|224051

Protein	Function_ID	Function_description	E-value
LR134535.1\|VEJ57748.1\|667090_667948_-\|Sulfate-starvation-induced-protein-7	gnl\|CDD\|270248	cd13530, PBP2_peptides_like, Peptide-binding protein and related homologs; type 2 periplasmic binding protein fold. This domain is found in solute binding proteins that serve as initial receptors in the ABC transport, signal transduction and channel gating. The PBP2 proteins share the same architecture as periplasmic binding proteins type 1, but have a different topology. They are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the family includes ionotropic glutamate receptors and unorthodox sensor proteins involved in signal transduction.	9.54005e-51
LR134535.1\|VEJ57751.1\|670901_671024_-\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	2.13814e-07
LR134535.1\|VEJ57756.1\|677969_679115_-\|CRISPR-associated-protein-GSU0053/csb1,-Dpsyc-system	gnl\|CDD\|378223	pfam09617, Cas_GSU0053, CRISPR-associated protein GSU0053 (Cas_GSU0053). This entry is found in CRISPR-associated (cas) proteins in the genomes of Geobacter sulfurreducens PCA and Desulfotalea psychrophila LSv54 (both Desulfobacterales from the Deltaproteobacteria), Gemmata obscuriglobus (a Planctomycete), and Actinomyces naeslundii MG1 (Actinobacteria).	4.3655e-56
LR134535.1\|VEJ57742.1\|662060_662756_+\|Staphylococcal-respiratory-response-protein-A	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.88077e-73
LR134535.1\|VEJ57758.1\|679829_682622_+\|Calcium-transporting-ATPase	gnl\|CDD\|319781	cd02089, P-type_ATPase_Ca_prok, prokaryotic P-type Ca(2+)-ATPase similar to Synechococcus elongatus sp. strain PCC 7942 PacL and Listeria monocytogenes LMCA1. Ca(2+) transport ATPase is a plasma membrane protein which pumps Ca(2+) ion out of the cytoplasm. This prokaryotic subfamily includes the Ca(2+)-ATPase Synechococcus elongatus PacL, Listeria monocytogenes Ca(2+)-ATPase 1 (LMCA1) which has a low Ca(2+) affinity and a high pH optimum (pH about 9) and may remove Ca(2+) from the microorganism in environmental conditions when e.g. stressed by high Ca(2+) and alkaline pH, and the Bacillus subtilis putative P-type Ca(2+)-transport ATPase encoded by the yloB gene, which is expressed during sporulation. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
LR134535.1\|VEJ57752.1\|671020_672697_-\|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	7.66489e-107
LR134535.1\|VEJ57759.1\|682638_683568_-\|Glutamyl-endopeptidase-precursor	gnl\|CDD\|226119	COG3591, COG3591, V8-like Glu-specific endopeptidase [Amino acid transport and metabolism].	1.65711e-23
LR134535.1\|VEJ57755.1\|676540_677968_-\|CRISPR-associated-protein-GSU0054/csb2,-Dpsyc-system	gnl\|CDD\|274005	TIGR02165, CRISPR-associated_protein_GSU0054_family, CRISPR-associated protein GSU0054/csb2, Dpsyc system. This model represents a CRISPR-associated protein from the Dpsyc subtype (a type I-C variant), named for Desulfotalea psychrophila LSv54. CRISPR systems confer resistance in prokaryotes to invasive DNA or RNA, including phage and plasmids. CRISPR-associated proteins typically are found near CRISPR repeats and other CRISPR-associated proteins, have low levels of sequence identify, have sequence relationships that suggest lateral transfer, and show some sequence similarity to DNA-active proteins such as helicases and repair proteins.	1.97981e-62
LR134535.1\|VEJ57741.1\|661491_662064_+\|Protein-of-uncharacterised-function-(DUF3060)	gnl\|CDD\|371435	pfam11259, DUF3060, Protein of unknown function (DUF3060). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed.	4.99045e-06
LR134535.1\|VEJ57739.1\|659465_660515_-\|Lipoate-protein-ligase-LplJ	gnl\|CDD\|223173	COG0095, LplA, Lipoate-protein ligase A [Coenzyme metabolism].	1.34664e-59
LR134535.1\|VEJ57754.1\|673676_676544_-\|helicase-Cas3	gnl\|CDD\|187827	cd09696, Cas3_I, CRISPR/Cas system-associated protein Cas3; Distinct Cas3 family with HD domain fused to C-termus of Helicase domain. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DNA helicase Cas3; This protein includes both DEAH and HD motifs; signature gene for Type I.	9.16592e-97
LR134535.1\|VEJ57743.1\|662752_663622_+\|Sensor-histidine-kinase-YycG	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.96784e-35
LR134535.1\|VEJ57747.1\|666223_667087_-\|Arginine-transport-system-permease-protein-ArtQ	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.92488e-52
LR134535.1\|VEJ57757.1\|679287_679743_-\|homoprotocatechuate-degradation-operon-regulator,-HpaR	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.63527e-16
LR134535.1\|VEJ57746.1\|665453_666224_-\|Arginine-transport-ATP-binding-protein-ArtM	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.16411e-122

>LR134535.1|VEJ57748.1|667090_667948_-|Sulfate-starvation-induced-protein-7
MALPLSRRAALFALGSTVLLGSCTIASDGKNTPNSASASEGALKTVTPGKLTIATGEPAYSPWVENNDPASGKGFEAAVAYAVAGKLGFANADVVWVRSTFDAAVAPGAKDWDFNLQQFSITEERRNAVDFSSPYYTTAQAVVTLKGSPVSGATTVAELKGALLGAQTGTTSHRMLTETVAPTTAPSVFNNSQDTVQALKGGQVDAIVVDLPTALYLVAAELDGGVVVGQFADTSGGDQFGLVLPKGSALTAAVTGAVDALRADGTLDSLTKTWLSETVNVPVLS
>LR134535.1|VEJ57747.1|666223_667087_-|Arginine-transport-system-permease-protein-ArtQ
MNETVDDFEVVSDIELGRRRYRRRQTIRSVLISAVSTVVFAVVIWLVLENSPGWQVTRETFFSAHYFAATLPEVAVGLWLNVQILFFAVIGVAVLAVILAVLRSLRGPVFFPLRFFAAAYTDLFRGMPFLIVLYLIGFGIPALNPTTRIPAALLGTVALVLTYSSYVAEVLRAGLEAVHPSQRFAARSLGLSHGQTLRYVVIPQAIRKVTPALMNDFISMQKDVGLISVLGAVDAIRAAQIQQATTYNFTSYVVAGLLFVAFSWPFIRLSDWYTARLREREQTGGTV
>LR134535.1|VEJ57746.1|665453_666224_-|Arginine-transport-ATP-binding-protein-ArtM
MARLKPTRADDHAGPVLEMQGVVKRFGRNVVLRGLDLSVGSHEVVVLLGASGSGKSTLLRTANLLERVDDGRIFLAGTDITDPRIDVDAVRARIGVVFQHYNLFPHLSVLDNITLAARKVHGVERGVAEARGRELLERIGLSDKARAFPDRLSGGQQQRVAIVRALATNPELLLLDEITSALDPVLVGEVLDLVLDLKRTGSTILMATHEIGFARSAADRVVFLERGQIIEQGPPERVIDDPQESATKDFLARVLR
>LR134535.1|VEJ57745.1|664668_664863_-|Uncharacterised-protein
MKVITVQTCTDTANYNVVDSKTGKPIMKPGERPIYLAWNIDVVKTGEGWKVGDATNENALRCPA
>LR134535.1|VEJ57744.1|663686_664139_-|Uncharacterised-protein
MDQKPQPHHLGPIIKTVTQSGHSITATAAVTHLTWEMGNGDTKTCDKGIEHPEHQTRNEKSPSCGYIYHQTGNYTITATAHWVIIWTGLGQQGTIEMDLTAQVHTKVVEVSAVNIPNNKHGTPTTPSPPVPTSTPSREAPCPTNHNKHGC
>LR134535.1|VEJ57743.1|662752_663622_+|Sensor-histidine-kinase-YycG
MRKPVWVWAVAVVGVLAAAGMRIAGETQMFKVGVELWALPLLAGLLVPVVVMLAGWRRGRNARAVEEAVEGVKAEAREAHRTFVGRLDHELKNPLMALRVGLGEVRDPVLAESMRVQVDRLASLVAELRKISEIDSYPVADEPVDVSEVVSEVIETVVPGDREMVVAFPRAPRPLPPVRGDRDLVFLAIYNVVSNAVKYSSPGATLEVRGMEERGHVVVDVSDTGRGIPASEVDQVWGELARSKEVRHIPGNGLGLPMVAAVLRRLGGACELSSIQGRGTTVRMRLPLL
>LR134535.1|VEJ57742.1|662060_662756_+|Staphylococcal-respiratory-response-protein-A
MSSVLVVDDDPMIRDHLARTLERAGFVAFTAADGVAALEVVGKQHPDLIVLDVLMPRADGREVLARLRRGGDWTPVILLTGVGQSGTRADALEKGADDYLNKPFDPAELVARIRAVLRRGQLGRTLTHASRIRGGGLELDRLAKTVTARGQAVQLTPKALALLEYLMVHHGETFSRDHLLEQVWGVEFAITTRAVDHRVAELRKVLGARGLEVIDTVQGVGYRFHPEVRAA
>LR134535.1|VEJ57741.1|661491_662064_+|Protein-of-uncharacterised-function-(DUF3060)
MKTNLIRIALAAAAVTALGLSACSAGAENKPAGNTQAVSTTQDANKNTPSPGNVATASNGGDANVTASSDGSGNKSGSKDKGDSDDKPCVGNPNVSSSNGVVTLSGHCDTINITGSGNQVTFESADKVILSGGSNVVVGQELDDVEITSSGNSVTVSDDLDEVTVSGSGNTVSSQGVEKKKDTGSGNTIS
>LR134535.1|VEJ57740.1|660675_661350_+|Uncharacterised-protein
MKTILTRTAIAALAIASFGFAACTAGVEAKPQDAPGNAGSSQQAPAQTDSPTPQQTKSEDSSSSETKNGSGGVTAPGVTVGPGGVKAPGVTVGPGGVKAPGVTAGSSGVTASAGSVRSADCEKDSVVEETGAVVRFSGHCESIVIKSTGAVVEYDQVDKMVIEGTGIAVKGGDIKSLKITGDGAGVVSSGDVGEVTISGTGNAVTVSGTVGKVKDTGIGNAVNS
>LR134535.1|VEJ57739.1|659465_660515_-|Lipoate-protein-ligase-LplJ
MHGEYKVPDGKLVAVDLDVVDGKLSQVVVSGDFFLEPDESLDDIVRALTGLPHTSSVADLAAAINSRLPKDARLLGFSPEAVGIAVRRALGHATNWDDHTFDVIGPVTLDPRLHVALDEVLAARMARGEIGPSLRIWDWDQPLVVIGSFQSYRNEIDEEGRERHGINVVRRITGGGAMFMEPGNCVTYSLLVPGSLVEGLSFERSYEFLDQWVMGALAELGVRARYVPLNDIASDKGKIAGAAQRRLTSGVVLHHVTMAYDIDADKMLQVLRIGREKLSDKGTKSANKRVDPLRSQTQLPRDQIIDSFLKHFESRYSTRRRNYTDDELAAAAELVEKKFATPEWTRRIP
>LR134535.1|VEJ57750.1|670733_670850_-|Uncharacterised-protein
MNLAVDSVVIVDLGEIGEDRFIFVGHHEDLPTRGPQIV
>LR134535.1|VEJ57751.1|670901_671024_-|CRISPR-associated-endoribonuclease-Cas2
MKTRRRRYLVAYDIREPGRLRRICKLMEAHGERLQYSVFI
>LR134535.1|VEJ57752.1|671020_672697_-|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO
MTVRPDIPGLPETVPARMLNEFVYCPRLFHLEWVQSRFTTSDDVEEGRYLHRVVDEESGDLPDKSEAWGGRTARSVSLSSPGLGLVAKLDLVEDGGNGSVVPVDYKKGHPDKTGAPWPNDRTQLLIQALLLKEAGYVVERAEIWYAETRRRVVIRIDETALSEITETLKDAWRVAADPKPPPPLRNSPKCPRCSLVGICLPDELTSLKIPPRERRPLKRLMAPILEGRPVYVTMQGSTVGIRNDRLEVRLDGELQASYRLIDVSQLCVFGNVTVSSRAVRELMSNDLPILWFTYGGWFAGMAEGLPGKNVDLRIAQFGASEQKRLEAARNMISGKIRNSRTLMRRNSRTEAERIGNQLKELAIQATKAASPGQLLGIEGTAARLYLASFPAMIGDNTRIDVSDFHENGRSRRPPPDPLNALLSFCYALLVKDLTVALASVGFDPYLGMFHKPRFGRPALALDLAEEFRPLVAESVVVQVLNNREVGPHDFRTRAGGCMLEPSGRKAVLRAYERRLDQEITHPQFGYKATYRRIMDIQARVLGAFLTGELDQYTAMVTR
>LR134535.1|VEJ57753.1|672693_673680_-|Uncharacterised-protein
MMNHVTLPALLGDSPLAILAAIGTLRLIHDFTDNNARLHWNTTDHRPVLTSSLATVDEVAEALVDIVRTMPEGVSVPGGPMGFPPPGEAPDKLRVPQGKLHSFAENLFPEISETESATMFSWLTSLITDLAATSEKSDSGSKNQKSNSQKRCSVSQFIASSGKQSIATMLKKPLEHVQKHPEYLHEALTGWVRVPGVTGEYLDHRAAWKAIDDGRGRTGRMRGVPGATWLALMSYPIWTTTAAGKKPRTSGWHLVGKGRRSIQELRLPLWVEPLGPLAIKALVEHPELDGDLDVPLNQKIRLLGIFHVCRARRAPSEHSAGLLIPAQR
>LR134535.1|VEJ57754.1|673676_676544_-|helicase-Cas3
MIAGDFDLFMEELHGHRPFPWQSDVVADMLRAGTWPSLVDVPTGLGKTSMLDAAVFVLAMCAGGEAASGLGRRRIFLVVDRRIVVDQAELHGKRIAEALETASPGSVSEEVARRLRGLSGSPDGPVLPVVKMRGGATWDAAWLPLPDLPAIITGTVDQVGSRLFFRGYGVSARRRPIDAALVGTDSVIMIDEAHLAQALTASLEATSSLDSSQVLGLPRTSVVHLSATSTGRPEGWTTSFDEKAHLDDPTARARLAAPKTLTFVDTTKQRVVRDIAARAAEAVTGTDSRVLVVCNTVDRAREVHNRLLGSKGLPSGTEVLLLMGRSRPVDREAITAKVTELFGADREEKPGSAVLVATQTVEVGIDLDATALITETAPWDALVQRIGRVNRRGVLPAADVVVVEDNDPKPPVYGNVKVHTADFLRSRLKAPGTMDVSPLALRHMDVPAELTAEAPLLPLLLPAQLDAWARTSPAPSVDPPLDPYLHGIDTSVAPVTVAWRDELRNAWNETLPADEVGGAIDSLPVRAEECVEIPLGALRRWLCDAKPLPVGDTEDYDDFDDIPFGDDSESTVLRRVDDGSGPSTWAWVSGESLRPGDVVVVPTDSGGLDQFGWAPTSTDKVSDVSELATCRRGRAALRLDPGLPDRLGIPASTDFQDLVRDWRNCDDPDDREEFSSGIVSAVLAWLARHPDPESSSAWTSDDLATLRAQLAGNIVLTQTTEASSPILRVVSPETSWLNADDGNSDETSHLNRRVTLATHMKAVGARADGVARRLGLPEPVRQTVTDAARWHDLGKVDQRFQAMLFGGDPIRAELADEPLAKSGMPPGDRQQYRRARQLSGLPRGARHEAWSEVLVAEYLAELTEPYPGDPELLRHLVASHHGHARPFLPPVLDTGEHTLEAVVDGIQVVSALPTSVRLSDAERFSRLNARYGRWGLALLEAIVRCADMTVSSEGS
>LR134535.1|VEJ57755.1|676540_677968_-|CRISPR-associated-protein-GSU0054/csb2,-Dpsyc-system
MPVCLDICLMSERYEAGDGEDPRAPEWPPHPARVFSALRSVAESDEIAPLYEFEQLPPPLIHASAFAPCSISRSFVVTNARFNGEKTKSGKIKTGNQNHPARTSDLMKRIRSFPPDPRIQFVWPDDRDLSDEALAGLDALARRVPYLGRSTSPVMLAFRRVADFRPLPGLSTFEPTDHDRAECNIRVPFPGYLDELNALHELDQSSWQASRSHARQPYRLVRDESDAVAPTVVESPYPDLVILRFVDHRPPGNLVGLFTAALRAKVMSQTKNPLPPALHGHGFDGHPHVAYLGLPFAGFPHADGHLRALAVAIPGLDRAERRRILRGILGTDPDRIVDLQVPGFRRVFGLRYSPDEPLPASATAARWTRPARSWVSVTPLVLDRYPKKGDLAPAVVRSIQQAGLPAPVTVELSTQPLTPGAAHLTPKELPLRARGRLYRHVRMTFEHPVTGPVLAGAGRYFGVGLFAPEREGADR
>LR134535.1|VEJ57756.1|677969_679115_-|CRISPR-associated-protein-GSU0053/csb1,-Dpsyc-system
MTTLSLGSLQDKIRDPEFALARINATYQPGGGPGSRLFPPTFPTSRSDDSPYLMEERTCDGSSRRAVVLDQVPSQANRCEEALKTARQAGKIRLPLLRLTHDGAAKAVITGLDAPHRAFDAYWRDSLLDGEKFDRTPAGKALQATSLEDATALLQYDPATLVYGGWNSHRKGRQAKFPRFYSSEVVGWDPVVGTRKAGRMDPLNLTGARNGDGDEWTYSPAAAKNAKARLSEIGHGNIAPNPAHGGVTVTEVTRFSTLSLTAVRRIRFGSLGVNTQFAASTLLVALALLGDRLAFGGAGIWLRSGCDLVVEAETLEWIGRGGVVEPFSLSIGEAVSLYDEALEAAIESGVPMHLETIELTPSKALAAAIDFTVTKAESSGE
>LR134535.1|VEJ57757.1|679287_679743_-|homoprotocatechuate-degradation-operon-regulator,-HpaR
MSTDADETVADLHRLFSGLSRLASRMRLRNAMHPGIRNLAQTDAWLLSHLAATGPARMSALAEWQAVDRSTMTAQVKRLERAGLARRHTDPTDRRASIVTLTEDGEAACSEIRREASAFFADILSDWTPEQRRELIESMTRLSTALEEHLN
>LR134535.1|VEJ57758.1|679829_682622_+|Calcium-transporting-ATPase
MTTSPALQTADEALSAAGVDPGTGLSSVEAASRLVSHGPNELRSRPREAAWRRFLKQFADPLVYLLFGAMVISLVAWFLEGAGGLPIDVVVILLIVLANAVIGFVQENRAADAVAALADMTAARATVLRDGKLATIPAADLVPGDVLVLGEGDAVAADARLISASSLQVQEASLTGESEAVTKTVTPLAELGSLGDRHNMVFKGTAVARGVGRAVVTGTGMDTEMGRIATLLDETADEPSPLQREIAQISRTLGVLVIGIAVVVMIVVAAVNGVSSFHEAVDILLLGVSLAVAAVPEGLPAILSLVLAIGVQAMARRNAVMKDLHSVETLGSVSVIASDKTGTLTKNEMTIREIVTPSGRVELTGTGYEPVGAAVITGDEARTRAEAERTLAAGALANNAQLAKVNGTWEVQGDPTEAAFLVAQHKLEGVSERIGAWERIGEVPFTSERKMMSVLGRRTTDEHVRLFAKGAPDVLLERCTAELVGGDVVPLSDERRGRIEADIERLSAEGYRTLGVARRRALEQDPATFAEDAEHDLVHLGVVAIIDPPRPEAVEAIAEAHRAGIRTVMITGDHPITAARIAADLGITEGSSRALTGREIESMDEEELGRAVKDVDVYARVSPEHKLRIVDALQAGGQVVSMTGDGVNDAPALKSADIGIAMGITGTEVTKEAGEMILGDDNYSTIVAAVRQGRGIFDNIKKFMRYLLSSNMGEVATVFLAVLLGGLIGLADPANSAAAVVPLLATQILWINLVTDSGPALAMGVDPETDDVMGRGPRKLTDRIIDTHMWQRIIGVGLVMGLLTLLIYDLTLPGGLVGGLEDLATPGSQFAVARTTVFTALVFMQLFNALNSRSDTGSAFTHMFSNAWLWGSVALVAVLQALVVEVPFLQSAFGTAPLDWIHWAVAVGAGAAVLLYEEVVKLLRRTFGAP
>LR134535.1|VEJ57759.1|682638_683568_-|Glutamyl-endopeptidase-precursor
MKKIRNSITSAAGAALLAAALLATSSPALQAAADDDPAPNPAEVSPVGIDSSGQSLTWQPDDATASSGDSVPGYKPDSIESAPSSIIGEDERVRLTDTTAYPNSAIVYISKGGKPYCTGWMISADTLVTAGHCVYSYERQEWTSGLEFSPGANGPERPFETATATQKWTDVAWVKNNDPRLDWGLVKLDKPLGDRTGWFGLTWRSEDYKDIGVELRGYPYDKAPGELWGMGGTVTESRGNQLCYSLDTFPAQSGSPLYMSDGAFAIGIHAYGTVRGQQQPGRECPQEYNAGTRITKGLYELFVDLKSRR

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Crispr_ID: LR134535_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134535_7

2217375-2217455

Orphan

Consensus_repeat	Method
CTGCGATTCGTGTGCAGGAGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134535_7

>merge|LR134535|7|2217375-2217455|CRISPRCasFinder
CTGCGATTCGTGTGCAGGAGGGGTTTACCTCGGGGACCCCAACCGCTACCCCGAAATCCTGCGATTCGTGTGCAGGAGGAG

>LR134535|7|7|2217375-2217455|CRISPRCasFinder
CTGCGATTCGTGTGCAGGAGGGG	TTTACCTCGGGGACCCCAACCGCTACCCCGAAATC
CTGCGATTCGTGTGCAGGAGGAG

Protein	Signature genes	Signature genes Name	Protein_function
LR134535.1\|VEJ59082.1\|2212834_2213170_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ59095.1\|2226725_2228870_+\|Serine/threonine-protein-kinase-pknB	unknown	unknown	gnl\|CDD\|270916
LR134535.1\|VEJ59089.1\|2220987_2222100_-\|Ferric-enterobactin-esterase	unknown	unknown	gnl\|CDD\|236695
LR134535.1\|VEJ59081.1\|2212280_2212871_+\|transcriptional-repressor-BetI	unknown	unknown	gnl\|CDD\|224228
LR134535.1\|VEJ59094.1\|2225981_2226611_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ59093.1\|2224898_2225906_-\|Ferrienterobactin-binding-periplasmic-protein-precursor	unknown	unknown	gnl\|CDD\|236806
LR134535.1\|VEJ59088.1\|2218632_2221002_+\|Calcium-transporting-ATPase-lmo0841	unknown	unknown	gnl\|CDD\|319795
LR134535.1\|VEJ59087.1\|2217458_2218643_+\|Octaprenyl-diphosphate-synthase	unknown	unknown	gnl\|CDD\|223220
LR134535.1\|VEJ59096.1\|2228945_2229875_+\|Predicted-permease,-DMT-superfamily	unknown	unknown	gnl\|CDD\|223769
LR134535.1\|VEJ59086.1\|2216281_2217169_-\|5,10-methylenetetrahydrofolate-reductase	unknown	unknown	gnl\|CDD\|273212
LR134535.1\|VEJ59083.1\|2213179_2213662_-\|Thiol-disulfide-oxidoreductase-D	unknown	unknown	gnl\|CDD\|239321
LR134535.1\|VEJ59080.1\|2210672_2212208_-\|Antiseptic-resistance-protein	unknown	unknown	gnl\|CDD\|184957
LR134535.1\|VEJ59084.1\|2213661_2213973_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ59077.1\|2208589_2209105_-\|Protein-of-uncharacterised-function-(DUF3090)	unknown	unknown	gnl\|CDD\|378626
LR134535.1\|VEJ59091.1\|2222881_2223913_-\|Probable-siderophore-transport-system-permease-protein-yfhA	unknown	unknown	gnl\|CDD\|227119
LR134535.1\|VEJ59079.1\|2210439_2210646_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ59092.1\|2223909_2224884_-\|Probable-siderophore-transport-system-permease-protein-yfiZ-precursor	unknown	unknown	gnl\|CDD\|376439
LR134535.1\|VEJ59078.1\|2209258_2210227_+\|General-stress-protein-69	unknown	unknown	gnl\|CDD\|223739
LR134535.1\|VEJ59085.1\|2214108_2216289_+\|Helicase-IV	unknown	unknown	gnl\|CDD\|226482
LR134535.1\|VEJ59090.1\|2222096_2222885_-\|Probable-siderophore-transport-system-ATP-binding-protein-YusV	unknown	unknown	gnl\|CDD\|224045

Protein	Function_ID	Function_description	E-value
LR134535.1\|VEJ59095.1\|2226725_2228870_+\|Serine/threonine-protein-kinase-pknB	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.01592e-107
LR134535.1\|VEJ59089.1\|2220987_2222100_-\|Ferric-enterobactin-esterase	gnl\|CDD\|236695	PRK10439, PRK10439, enterobactin/ferric enterobactin esterase; Provisional.	1.37344e-19
LR134535.1\|VEJ59081.1\|2212280_2212871_+\|transcriptional-repressor-BetI	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.29177e-09
LR134535.1\|VEJ59088.1\|2218632_2221002_+\|Calcium-transporting-ATPase-lmo0841	gnl\|CDD\|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
LR134535.1\|VEJ59087.1\|2217458_2218643_+\|Octaprenyl-diphosphate-synthase	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	3.71182e-62
LR134535.1\|VEJ59096.1\|2228945_2229875_+\|Predicted-permease,-DMT-superfamily	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	4.69586e-18
LR134535.1\|VEJ59092.1\|2223909_2224884_-\|Probable-siderophore-transport-system-permease-protein-yfiZ-precursor	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	7.53351e-63
LR134535.1\|VEJ59083.1\|2213179_2213662_-\|Thiol-disulfide-oxidoreductase-D	gnl\|CDD\|239321	cd03023, DsbA_Com1_like, DsbA family, Com1-like subfamily; composed of proteins similar to Com1, a 27-kDa outer membrane-associated immunoreactive protein originally found in both acute and chronic disease strains of the pathogenic bacteria Coxiella burnetti. It contains a CXXC motif, assumed to be imbedded in a DsbA-like structure. Its homology to DsbA suggests that the protein is a protein disulfide oxidoreductase. The role of such a protein in pathogenesis is unknown.	4.54047e-29
LR134535.1\|VEJ59080.1\|2210672_2212208_-\|Antiseptic-resistance-protein	gnl\|CDD\|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	8.48467e-48
LR134535.1\|VEJ59086.1\|2216281_2217169_-\|5,10-methylenetetrahydrofolate-reductase	gnl\|CDD\|273212	TIGR00676, 510-methylenetetrahydrofolate_reductase., 5,10-methylenetetrahydrofolate reductase, prokaryotic form. The enzyme activities methylenetetrahydrofolate reductase (EC 1.5.1.20) and 5,10-methylenetetrahydrofolate reductase (FADH) (EC 1.7.99.5) differ in that 1.5.1.20 (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while 1.7.99.5 (assigned in many bacteria) is flexible with respect to the acceptor; both convert 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as 1.5.1.20 and 1.7.99.5, this model describes the subset of proteins found in bacteria, and currently designated 1.7.99.5. This protein is an FAD-containing flavoprotein. [Amino acid biosynthesis, Aspartate family].	6.8275e-92
LR134535.1\|VEJ59077.1\|2208589_2209105_-\|Protein-of-uncharacterised-function-(DUF3090)	gnl\|CDD\|378626	pfam11290, DUF3090, Protein of unknown function (DUF3090). This family of proteins with unknown function appears to be restricted to Actinobacteria.	5.65065e-59
LR134535.1\|VEJ59091.1\|2222881_2223913_-\|Probable-siderophore-transport-system-permease-protein-yfhA	gnl\|CDD\|227119	COG4779, FepG, ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism].	1.47105e-74
LR134535.1\|VEJ59093.1\|2224898_2225906_-\|Ferrienterobactin-binding-periplasmic-protein-precursor	gnl\|CDD\|236806	PRK10957, PRK10957, iron-enterobactin transporter periplasmic binding protein; Provisional.	8.47566e-94
LR134535.1\|VEJ59078.1\|2209258_2210227_+\|General-stress-protein-69	gnl\|CDD\|223739	COG0667, Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) [Energy production and conversion].	4.52663e-86
LR134535.1\|VEJ59085.1\|2214108_2216289_+\|Helicase-IV	gnl\|CDD\|226482	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only].	2.48589e-69
LR134535.1\|VEJ59090.1\|2222096_2222885_-\|Probable-siderophore-transport-system-ATP-binding-protein-YusV	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	7.71566e-120

>LR134535.1|VEJ59086.1|2216281_2217169_-|5,10-methylenetetrahydrofolate-reductase
MSPTVAELLRDAASPTLSFEFFPPRTPEEQPRFEATVAKLGRFHPAFLSVTYGASGSTRDRTVAATAALGAAQHATVVGHLTCVSQSTDDLLRTLDAFVDAGVRDILAIRGDMPGGPQQPWEKHPDGLGNATELVRLIKAHGDFCVGVAAFPNVHQPDNDPELDARIVAEKAAAGADYAITQLFFESHRYVELVNRVRERGSQIPIIPGIAPLTVITQIERFASLADCPLPEDFVAALRAARNPAEVRSIGLSRAVNLCRELLAAGAPGLQFFTQNRWKATSEVLDAIGWGDRVS
>LR134535.1|VEJ59085.1|2214108_2216289_+|Helicase-IV
MSTSRGDLQREIALEQAHVDRVYENLAASTASARTLARSGAEIYKTDRDDYLREESGTALFERDAFAYQAAKRLAILDAEHEGLVFGRLDLNFPETRYIGRLGVRDAEYEPLVIDWRAPAAEPFYRATQATPMNVIRRRVLRCRDDNVIGLEDDLLDTSAETDLPILGEGALMAALTRARGRTMRDIVATIQAEQDEAIRAPYQGVTIIGGGPGTGKTVVALHRAAYLLYTNRARLEKGGVLVVGPSSVFMNYIERVLPSLGEESVTLRAVGAVAGDVLGMVSERVDAAPAATLKGSLRMLKVLRRLVRRPPNPAAEEVRVSVKGEVLKLDAVELAGIRESVLSNYKMNRGRAAATTSVARALAGKLTVDVELGPEEIDERIRDHQQFREFMDSWWPMLDAPTVLARLADRELLEELAPNLTARERDNLAESYQWLQTDDVEITGWSVADMALLDELLEMLGPVPAESHEEPVFIDFGNISELVTTSDLLRREHVADPDEDPQTTYAHILVDEAQDVTPMQWRMLRRRGPQASWTLVGDPAQSSYPDTAESERAVSDLVGRAPLRRFTLSTNYRSPSEVFGLAAKVITRVFPEASLPRAVRNTGLVPRLEETDEAGLAEAIIALSLGLAGHVSGTVGVIVPPSRLGATTRLAMSDPRLAALEERLIVVTALQAKGLEYDGVLVLCPDEIVAEAPGAERVLYVALTRATQRMTILDVGTSAWRAALS
>LR134535.1|VEJ59084.1|2213661_2213973_-|Uncharacterised-protein
MSGKQQAEPGRGNPARPWKIATGVLAAALVFCLGVLSQTLLSGRSQTDASASSPNAATTTATPETTRQTVDPSRKAQQEAEIAKLARRQENDPMAKGGSTPPW
>LR134535.1|VEJ59083.1|2213179_2213662_-|Thiol-disulfide-oxidoreductase-D
MIEYSDYRCPFCSVFAEETLPKLQPLIDDGTLRIEFRDLAVFGDDSVAAAAAARAAGKQGLFWEFQDALYRRLPNQGHPDVKDDLIMEIATQVGVPDMAAFEADYRSEETRTAVKNETAEGRRMGIDGTPFFFIGTRAISGAQPLETFQQIIAQEKAKAS
>LR134535.1|VEJ59082.1|2212834_2213170_+|Uncharacterised-protein
MVPGCGATNPVLTHVQHDDPLSAPVRSPRGQIFETYPEFLAAIAPGMRLCTSGFTGWGEVTGTTERSVLGTRDSDGAGAEVPQEALLDIRGRHCVRLDRARATIDRQGWEI
>LR134535.1|VEJ59081.1|2212280_2212871_+|transcriptional-repressor-BetI
MPRPRPHDDHLREQLLGIATETIARTGVEGLSLRTLATDAGTSTSAVYQLFGSRAALLDAVYLRVLEEFNRAQADAPMHEDPTEDLLELARAYRRWALENRNQFLVLVERITPSQEAVAGVVGHAVPVEDRVRRAMDKGALSGPLEQVVLSLWATVHGYTALEVAGVITGSDDDFEAIARATQRGWSPDAGQQTQF
>LR134535.1|VEJ59080.1|2210672_2212208_-|Antiseptic-resistance-protein
MTEEQNQNPPSGDPGAAAVASPRRWWILVALSLATTIIQFDQSGMTLALPHVQAELEATTQQLQWVMDAYSLALAAVVLTAGAVSDRYGRRKVFLLGIVVLAAGSLIGALAPDANVVIAGRAVMGVGGAMFMPGTLSIITHVFDRDTRSTAIGIWGAVTSLGVIIGPLISGAVLQIWHWRGIFILNVVMAAIAFTGVAALVPESRDPHPRRLDIPGALLAGVGLFGVSYAVIHSSSDGVTDTVVLAAAGIGAAALVLFWLRSSRGEVSMFDLDVARNPTFLGAALAAAATMFTMAGLLFMITQQFQLVDGFAALLAGVAVLPMAGGAVIASLLVPLLVKRLTARTLILLGLALIAGAAAVYGLAQPIRGYLPSLIVLILLGMGNGGVMVVANDLLMSSGPTSRSGLISSMNDTVQEIGTAFGIAVLGAVLASQYAVSLRRSMPGVADGSFTATLSDAGTDASVREAALAAFGDASRMAGLTAAGIVVLAVMVIAFALRKVVAAKSGEDEED
>LR134535.1|VEJ59079.1|2210439_2210646_-|Uncharacterised-protein
MALIHNDCRGLCDWHAAGELHDGLPLFRCNGCRSEWTPAERWTPINADGEMSEGVLAARAMPKVRRDR
>LR134535.1|VEJ59078.1|2209258_2210227_+|General-stress-protein-69
MEYRALGGSGLHVSRIGLGTMAWGRDVEWPVVRELVHDFVEGGGNLIDTAPAYGGGVAEQMIGKLLATGIPRDSLAIATKAGFVIRGGRRIIDTSRAALLNDLEGSLRRLRTDHVDLWQVHAWGDAPIEETLSALDSAVSRGLARYVGVSNFVGWQTATAATWQEAMSGRTKLASVQVEYSLLARRAEVEVIGAAQYHTLGLLAWSAMGRGALTGRYRRGVPKDSRAASEHFGWFLEPYLQPRSRAVIDAVAKAADGLALTPAQVALMWVRDAPQVASALVGPRTPDHLAELLEAETKQLVPPIVAALDDISGGPNQFRIAD
>LR134535.1|VEJ59077.1|2208589_2209105_-|Protein-of-uncharacterised-function-(DUF3090)
MMYEFPHPDRVVVGALGPVGERSFVIQIRQGEHMVAVGVQREAVLSIARRIDSLLREATALGWLGEPPETDPELGPLDAPVEVLFNVGAIGWALDTRRGAIQLEFYPDDQDVQEVAAIVQVWLYPGVAKRFAARARIIVATADPSCPFCSQPVHAAGHICPRSNGYRAPLF
>LR134535.1|VEJ59087.1|2217458_2218643_+|Octaprenyl-diphosphate-synthase
MRFRHWPFLRHSPVQPASIKLYRGLIDSTSKLGRMLIPPAHDPMSSVFISVVGRTLAEFLDGQAGLADRTGATAVLDAAHACVAGGKRLRPAFCYWGYVAAAGRPTDPGPLLRAAASLDLLHASLLVHDDLLDGSDTRRGAPSAHRRFEALLPGPRAARFGEAAAILLGDVLFSWSAEMFENAGLSPEAVRRAAPVLATMRSEVLLGQYLDVAAAFGATDRSTPRAQADTAEKVLEFKSARYSVRRPAELGATLGEAPPGLLAALGTYGSLLGRAFQLRDDILGVFGDPGATGKPAGDDIREGKRTVLVLAALENGDARQHDTLDSLLGTPGLTEEDLTTAREIIEATGARNSCEELIARSTTDALTALEGADMDAEGHSALITLAGLATDRDR
>LR134535.1|VEJ59088.1|2218632_2221002_+|Calcium-transporting-ATPase-lmo0841
MTGELQGLTAGQVVERVREGKVNTLPERSGRTTWQIVRDNVFTRVNAMLAVLFVIVAATMQFAQGAFAILIVANSIIGMVQELRAKRTLDNLAVIGEAHPVVLRDGQRVSLPRDQVVADDLIALSPGDQVVVDGEVVAADYLEVDESMLTGEADPVAKSVGDELMSGAFVVSGSGVYRATKVGAEAYAAQLTAQAAKFTLVNSELRAGIDRILKFVTWLLIPAGLLTIWVQFRQPGTTWQESALRMVGALVPMIPEGLVLLTSMAFALGVIRLGRRKCLVQELPAIEGLARVSVVCADKTGTLTQNAMTLGEVIPLAGSADEVTEVLAQLVAADPAPNASMTAIAEATPAASSPWEVTARAPFTSAKKWSGVSFGTRGDWVLGAPDVLAPADVAARAEEIGSTGRRVLLLGRASEPVDSPGAPGAVTPVALLVLDQLVRPDAADTLAYFNDQHVAVKVISGDNAASVGAVTRSLGVSVAEAVDARTLPAEGEEFTEKIAGADVFGRVTPQQKRAMVAALQSRGHTVAMTGDGVNDVLALKDADLGVAMGSGSPATRAVAQIVLLDDRFATLPHVVAEGRRVIGNIERVAKLFLSKTVYAVFLALVIGLMGLPNPFIPLQMTVVGWFTIGIPAFLLSLPPNKERARPGFVRRVLSLAVPSGVIIGTVSTITYVVTRGFGAVSAVVQAQASTATLAALIITSVWVLAVVARPWVWWRLGLVVVSYAFYLAMFLIPWAWLRGQLLLDLDNPSTILFGVVAGLVGAGLVEAVWWLTARHRGEPARIWRGSDEG
>LR134535.1|VEJ59089.1|2220987_2222100_-|Ferric-enterobactin-esterase
MTMHLPPTPLSATGAPHPADPELPDQLDHSPIMGKRCVIDGVEMVEVTFVAHEPRGCEVLVHLNSLTDAIRTRLDPAVMTPVGDTGIQALSWWLPADGCYSYRYWRSDEIPRDIGATREGWLRVHREGEPDPLNPETLPAFDLREQSVWRGPDFHPAPWTPAGEAEQRWRLHDGGRFAVLPGDDRTLVLFDGLRWRLAGVASALRAAGFGHTVVAVDTGEGEQRAAWLTTARGCAPLVERARELAGTGREVIAAGQSFGGLACVELATHRPDLVTAVIAQSASLWFAGDPVPDPKAEGTLLRDLTAGTRTLGVPVVVQAGTDERGLIQGARRLAGIAERTGRLVSAEEFRGGHDLSWWRHGLLSGLSALV
>LR134535.1|VEJ59090.1|2222096_2222885_-|Probable-siderophore-transport-system-ATP-binding-protein-YusV
MTGTAQEFPLKASSVRLGYDRKIVIEDITLEVPEGELTMLIGPNGCGKSTLLKALARVLAPKAGYVYLGGTDIHQLRTTAVARRLGFLPQRQSVPPGIKVLDMVSRGRFAHQRFWSRWSQEDEKAVASALEVTGLTDLQRADVDELSGGQVQRVWLATVLAQDTPLLLLDEPTTFLDIAHQYEVLKLVRGFRDAGRTVVVVVHDLNQATRFATNLVVMKDGAVVASGLPAEVLTAELVESVFGLPVLVVPDPVTGTPMVVPR
>LR134535.1|VEJ59091.1|2222881_2223913_-|Probable-siderophore-transport-system-permease-protein-yfhA
MSLQVRSVRLGPVSFRARPRTWLVAALAWGIALAGAIAVLFSGSVNMTPEQFWAALAGVGERADMLLLWEFRMPRAVTGLVVGACLGTAGCLFQALSRNALGSPEIIGLTGGAALGAVASVIVFRSFGWGTAVGAIIGCLGAALLTWVLSPRGFGGGNRLILIGLGVASLIQPVTVLLLTRADSDSATSARLWLTGTLNARNWSHAAVGAVLFAVILPFALLISRHLDAAAPGEDLAAGLGVSRRFTQWTATGVGVALTAAAVAVAGPISFIALAGPHVARRLLKGPTAPAGVAAGTGAALLVAADLVGANLPGGLQLPVGVTAGLLGGAYLLLLLNGQERKK
>LR134535.1|VEJ59092.1|2223909_2224884_-|Probable-siderophore-transport-system-permease-protein-yfiZ-precursor
MLLGLVILLPCLAMASFLFGSGEVPAEQVMAVLSGGGTGQQRLIVLGMRGSRTLIALVAGAALGIAGVLVQALTRNPLAEPGLLGVNAGAACAVAIGLGLARSLPIAMMMLVSLVGALVSGLVVTGAAGAWRGRHDPVRIVLVGAAWSAVVSAITTGMLLSDPRIYAEFRFWDAGAVMPRPLDLVIAAAGTLGAGLLAALLLARSMDALALGEEFAKGLGLAAGRARMLVALTCLVLCAAATALVGPVSFLGLIAPFAARLVVGPRHRSLIWFSALLGGVTLLAADVLGRVVNPPAEVQAALMCALLGAPLFIGLARARRGVQL
>LR134535.1|VEJ59093.1|2224898_2225906_-|Ferrienterobactin-binding-periplasmic-protein-precursor
MTNPLFNPISRRTFSGLVPVLLTLGLTGCGSGGTSGGGDASSPASARTVTHDLGETVINGTPKRIVSTSVVLTGTLLALDAPVVGSGASKPGAEGFDDVGFFSHWSATAKERGVKALYANSKLDVEAVTAEKPDLIIIASTGGDSTKDDYDSLSRIAPTVAINYNSESWQTVTRKVADVTSTQARAEELTKTFNSRVTELKAGMSGVPTDPVQAIVYTPSNGLSFAKPGGPHDEIFSALGFKLAEAPASSGEEGANRKDFVFATVEQSVQALTSETLLLVSGDDKTVEQLKADSNYNTTQTVSSGKLVPLGISSFKLDYYSALAMAETLAAAYSG
>LR134535.1|VEJ59094.1|2225981_2226611_-|Uncharacterised-protein
MTVMHSLRSRILLARVAVQLPLADAGDRLPGLVLGGADVAVLTTGGAADRRRDLKILRDLERYLGQRVLLAVDTPELEADVRVLFPGEQDRSRPHQWALLGQAVQEQRQIVEPDGAFQFLAVPGSSPGSPLLRAAVENQPPLRRDSVPWFAAGGFDVGSVQALVETGVRRVWLAEGGTVEELEQIDEILRRAWGEDPAYEDYLDFAVRA
>LR134535.1|VEJ59095.1|2226725_2228870_+|Serine/threonine-protein-kinase-pknB
MNKSSTYDPMVGSVLDDRYEILAKLARGGMATVYRARDRRLQRTVAVKIMRTDLGEDDEFAAKFDREARSAALINHPAVVSIFDQGISRGQPYIVMEFIDGETLRRLIARDAPLEPVLALDYLEPIASALAAAHDAGIVHRDIKPENVMISTRGHVKVADFGLARQTESPQMTATGVLVGTASYLPPELVTHARPDSRSDIYSTGIVLFELLTGKKPHVGENNYQIAYAHVNIDVPAPSAKLRELGFPGFIPDYLDALVAACTARDPKARVADGRELMDKLRRVRTELASNPGQHNPALAAQLRPLPGDGDAATQQISPRPEPRPRPLKELPPIPARPRSAETPDPVVEEVSPDAVTAIVQPQSLRSPASAPSPRSATSARSASSAGEPPRATLPGPGRNGSPSSHRTPIFPQFSQDPIYRRRRGIMLFVLVLVVTAIVVSVSWWWAEGRFTTTPEVTNIPQEQALQALKANGLEYTTQEAFSEDVAVGSVISTDPAGNARTLRGTKVAVTVSKGPERYAMPEVVGQELSRARSAIESTNLAVGQVKEDWSESVEAGLVISASASAGDLLPPGAKIDLVVSKGRQPITIKDYKGTDADQASRELKKQGFTVEVSEEHSDTVAAGQVISQDPASGTGHRGDTVKLVKSLGPEMVTVPDVARKRTDEAQKELEGAGFKVEVQNNSIFPAPLGFASGTNPAAGSTAPKGSTVILYVT
>LR134535.1|VEJ59096.1|2228945_2229875_+|Predicted-permease,-DMT-superfamily
MDSNRRFLPSFALLLAAAAWGSTVVVAKGAYESSMTPAHLLISRLTLTALCLLPAFLPHLRMKRETRVRGIILGLIFNTGLVLQMVGLEHTPPSLSGFITASYVVFTAILTPLIMKQPTPGRTWIAVSLTLAGIGILALGNDGGGNDGFGFGTAITLLGAVLFALHIIFLGRWVEPETVQSLTLMQALTGAVGMLCFLPFADYQLPATWDLWWPVLYLGIFCGAVTLFLQSWAQSYVPATTSAVIICSEPMWAAVFAIGFGMEELTWQVLLGGGLVVAALLLTAWPGRRAKFLETLVEELRSRRARRRS

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Crispr_ID: LR134535_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134535_8

2856561-2856645

Orphan

Consensus_repeat	Method
CTCAACCAGCTTTGAGGCGGGAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134535_8

>merge|LR134535|8|2856561-2856645|CRISPRCasFinder
CTCAACCAGCTTTGAGGCGGGACAGTTTCGACACGGCCCACTCGCTGACGCTCGCAGGCCGACTCAACCAGCTTTGAGGCGGGAC

>LR134535|8|8|2856561-2856645|CRISPRCasFinder
CTCAACCAGCTTTGAGGCGGGAC	AGTTTCGACACGGCCCACTCGCTGACGCTCGCAGGCCGA
CTCAACCAGCTTTGAGGCGGGAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134535.1\|VEJ59682.1\|2863333_2864293_-\|bile-acid-transporter	unknown	unknown	gnl\|CDD\|223462
LR134535.1\|VEJ59677.1\|2856737_2857367_-\|HTH-type-transcriptional-repressor-KstR	unknown	unknown	gnl\|CDD\|366102
LR134535.1\|VEJ59685.1\|2867766_2868396_-\|Lipoprotein-releasing-system-ATP-binding-protein-LolD	unknown	unknown	gnl\|CDD\|213222
LR134535.1\|VEJ59668.1\|2841626_2842949_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|143620
LR134535.1\|VEJ59686.1\|2868407_2869655_-\|acidobacterial-duplicated-orphan-permease	unknown	unknown	gnl\|CDD\|223650
LR134535.1\|VEJ59678.1\|2857520_2859173_+\|Oleate-hydratase	unknown	unknown	gnl\|CDD\|237575
LR134535.1\|VEJ59681.1\|2861745_2863038_-\|enterobactin-exporter-EntS	unknown	unknown	gnl\|CDD\|340863
LR134535.1\|VEJ59670.1\|2845963_2846434_+\|NUDIX-domain	unknown	unknown	gnl\|CDD\|239217
LR134535.1\|VEJ59684.1\|2866007_2867576_+\|Levanase-precursor	unknown	unknown	gnl\|CDD\|350134
LR134535.1\|VEJ59679.1\|2859504_2860281_+\|Polyphosphate-glucokinase	unknown	unknown	gnl\|CDD\|224851
LR134535.1\|VEJ59672.1\|2846646_2849334_-\|DNA-topoisomerase-1	unknown	unknown	gnl\|CDD\|236048
LR134535.1\|VEJ59675.1\|2852788_2853685_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ59683.1\|2864765_2865620_+\|Fructosamine-3-kinase	unknown	unknown	gnl\|CDD\|367711
LR134535.1\|VEJ59667.1\|2841000_2841630_-\|Thymidylate-kinase	unknown	unknown	gnl\|CDD\|234814
LR134535.1\|VEJ59673.1\|2849421_2850570_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|380076
LR134535.1\|VEJ59680.1\|2860652_2861492_-\|Undecaprenyl-diphosphatase	unknown	unknown	gnl\|CDD\|234712
LR134535.1\|VEJ59671.1\|2846430_2846595_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ59674.1\|2850870_2852532_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|380076
LR134535.1\|VEJ59669.1\|2843408_2845415_-\|Kynurenine-3-monooxygenase	unknown	unknown	gnl\|CDD\|379199
LR134535.1\|VEJ59676.1\|2853874_2856226_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|236090

Protein	Function_ID	Function_description	E-value
LR134535.1\|VEJ59682.1\|2863333_2864293_-\|bile-acid-transporter	gnl\|CDD\|223462	COG0385, COG0385, Predicted Na+-dependent transporter [General function prediction only].	8.53207e-39
LR134535.1\|VEJ59677.1\|2856737_2857367_-\|HTH-type-transcriptional-repressor-KstR	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.71676e-15
LR134535.1\|VEJ59685.1\|2867766_2868396_-\|Lipoprotein-releasing-system-ATP-binding-protein-LolD	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	4.90243e-75
LR134535.1\|VEJ59679.1\|2859504_2860281_+\|Polyphosphate-glucokinase	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	9.35544e-32
LR134535.1\|VEJ59686.1\|2868407_2869655_-\|acidobacterial-duplicated-orphan-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	2.3564e-08
LR134535.1\|VEJ59668.1\|2841626_2842949_-\|Uncharacterised-protein	gnl\|CDD\|143620	cd07374, CYTH-like_Pase, CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases. CYTH-like superfamily enzymes hydrolyze triphosphate-containing substrates and require metal cations as cofactors. They have a unique active site located at the center of an eight-stranded antiparallel beta barrel tunnel (the triphosphate tunnel). The name CYTH originated from the gene designation for bacterial class IV adenylyl cyclases (CyaB), and from thiamine triphosphatase. Class IV adenylate cyclases catalyze the conversion of ATP to 3',5'-cyclic AMP (cAMP) and PPi. Thiamine triphosphatase is a soluble cytosolic enzyme which converts thiamine triphosphate to thiamine diphosphate. This domain superfamily also contains RNA triphosphatases, membrane-associated polyphosphate polymerases, tripolyphosphatases, nucleoside triphosphatases, nucleoside tetraphosphatases and other proteins with unknown functions.	0.00120588
LR134535.1\|VEJ59681.1\|2861745_2863038_-\|enterobactin-exporter-EntS	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.25226e-33
LR134535.1\|VEJ59667.1\|2841000_2841630_-\|Thymidylate-kinase	gnl\|CDD\|234814	PRK00698, tmk, thymidylate kinase; Validated.	5.2848e-85
LR134535.1\|VEJ59684.1\|2866007_2867576_+\|Levanase-precursor	gnl\|CDD\|350134	cd18622, GH32_Inu-like, glycoside hydrolase family 32 protein such as Aspergillus ficuum endo-inulinase (Inu2). This subfamily of glycosyl hydrolase family GH32 includes endo-inulinase (inu2, EC 3.2.1.7), exo-inulinase (Inu1, EC 3.2.1.80), invertase (EC 3.2.1.26), and levan fructotransferase (LftA, EC 4.2.2.16), among others. These enzymes cleave sucrose into fructose and glucose via beta-fructofuranosidase activity, producing invert sugar that is a mixture of dextrorotatory D-glucose and levorotatory D-fructose, thus named invertase (EC 3.2.1.26). These retaining enzymes (i.e. they retain the configuration at anomeric carbon atom of the substrate) catalyze hydrolysis in two steps involving a covalent glycosyl enzyme intermediate: an aspartate located close to the N-terminus acts as the catalytic nucleophile and a glutamate acts as the general acid/base; a conserved aspartate residue in the Arg-Asp-Pro (RDP) motif stabilizes the transition state. These enzymes are predicted to display a 5-fold beta-propeller fold as found for GH43 and CH68. The breakdown of sucrose is widely used as a carbon or energy source by bacteria, fungi, and plants. Invertase is used commercially in the confectionery industry, since fructose has a sweeter taste than sucrose and a lower tendency to crystallize. A common structural feature of all these enzymes is a 5-bladed beta-propeller domain, similar to GH43, that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	5.24916e-130
LR134535.1\|VEJ59672.1\|2846646_2849334_-\|DNA-topoisomerase-1	gnl\|CDD\|236048	PRK07561, PRK07561, DNA topoisomerase I subunit omega; Validated.	0
LR134535.1\|VEJ59683.1\|2864765_2865620_+\|Fructosamine-3-kinase	gnl\|CDD\|367711	pfam03881, Fructosamin_kin, Fructosamine kinase. This family includes eukaryotic fructosamine-3-kinase enzymes. The family also includes bacterial members that have not been characterized but probably have a similar or identical function.	1.1656e-65
LR134535.1\|VEJ59678.1\|2857520_2859173_+\|Oleate-hydratase	gnl\|CDD\|237575	PRK13977, PRK13977, myosin-cross-reactive antigen; Provisional.	0
LR134535.1\|VEJ59673.1\|2849421_2850570_-\|Uncharacterised-protein	gnl\|CDD\|380076	pfam17961, Big_8, Bacterial Ig domain. This entry represents a bacterial Ig-fold domain that is found in a wide range of bacterial cell surface adherence proteins.	0.00398726
LR134535.1\|VEJ59680.1\|2860652_2861492_-\|Undecaprenyl-diphosphatase	gnl\|CDD\|234712	PRK00281, PRK00281, undecaprenyl-diphosphate phosphatase.	3.49979e-98
LR134535.1\|VEJ59670.1\|2845963_2846434_+\|NUDIX-domain	gnl\|CDD\|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	3.76644e-15
LR134535.1\|VEJ59674.1\|2850870_2852532_-\|Uncharacterised-protein	gnl\|CDD\|380076	pfam17961, Big_8, Bacterial Ig domain. This entry represents a bacterial Ig-fold domain that is found in a wide range of bacterial cell surface adherence proteins.	0.000139456
LR134535.1\|VEJ59669.1\|2843408_2845415_-\|Kynurenine-3-monooxygenase	gnl\|CDD\|379199	pfam13460, NAD_binding_10, NAD(P)H-binding.	5.54271e-38
LR134535.1\|VEJ59676.1\|2853874_2856226_-\|Uncharacterised-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	3.67064e-05

>LR134535.1|VEJ59676.1|2853874_2856226_-|Uncharacterised-protein
MTDVRKTSPWRRFIAVLAALVLAVLGIPAHDTPARAEENDAIKFGPVTLTHVTETGDPVPHPGRQLLRGNFFFLDVSFDATAANPQPGDTFSISMPGPFVNRDAGNSQREVIKPLMVGATRVGDCNIKASLITCTLNDAVRGRTDILGTLRAQLVADGVTSRTSSTFVINGQNHVLQHPWGEDIIAPGIVPFTPGTRAVKGATGVGSGSKVINWRVIFGGAWLKNNYPNGGPVTIKDTISVGMEVPDPSTVQLIEVHGDPVTGKATDRVVAKGNGTGELDGFKVTPSIEGRTVTFKVEGPLSTEKDYRVDFSTPFTGGERVVPGFQYTNAATFVEAGHTTPTAIRSYFESFKAIVTYKQGFGGFEVGKNIRGDVVPPRGQKFDVTVNYALPAGTTAADYPGWDAPENPTKLTVTAGNTTPYMPTFPKGTVVTLSEDTSSADPATPGIAWGAPVFSSANNKVSINGDKTQATFTVEDQVTLPVSLMNTTEASTNGAFAISKAVVDGGSTGADTFSVNYRCSAAGEGGIAAEGAVDVSAGAEKVVGRFPAGTTCEVISEDETAAARAGYSLAVDKGQPVTVVKDDTVRVNVTNTYTKDLGAFAISKTLVSGGSEGTDSFGIEYKCSAAGVDDDGAVAATGTVAVTAGVDRVVGRFPAGTTCEVVSEVPSPRAGYALAVDKGQAVTVVKDDTVKVNVTNTYTKESAPSPGPSASPSVVPSVSPSPQPTGVPSVSPSQSGGPSASPGPTSSVGPTATVNPTASGVPAPTGQGTRRPPVRPGLPRTGS
>LR134535.1|VEJ59675.1|2852788_2853685_-|Uncharacterised-protein
MTTWLEKLLAPDLLEAYLERGYALNFGYAVSADSINPEDPAKDLVAALDLDGPDGPLAGADVVHTLRFPLLPTDTVYPAMGGTTDEERAVARGDFLELPPFNGDGVVALPSDPQASRLYVDPTILRAGAQILRRESGGAAAEVVATYRGLFMGWKKPDGTKTPPGSPDPLSMQAFRVKEADSFSPGQFNFGEDGSLRDVIGLRRDDNGAQRRIVIELDQIAQAGVVKVHGTWEGIPVRAMRITEDGERWEIMSLAHDAHAAQERGMRRVEAGVYSTLVAPHEALTTFTLLSMPSWPQG
>LR134535.1|VEJ59674.1|2850870_2852532_-|Uncharacterised-protein
MNHPRSLLRRAAGAAAALVVASAALLSAGSSPARADQNTDIKFGPVTLTHVTDKGEAIPAPGRQLYKGDWFYLNVDFDATKANPKPGQSFTIDLPEPFVNRDGGNSRGDVIKPLEYTDSKGATVKAGECKVDRSRITCTFGDAIEGKLDVVGKIQAQLLALGTTDKTSSVLTINGKEYTVAHPWNEDITLRSAVQFKPSTRLTKGAKGVGTNSTWINWRVLLGGSWLKANYPNGGPVTATDVIQDGLEVPDPATIKLVEVQAGPGGTGETERVVATADGKVKKDGYGIQASFEGKTVTFKVTGSLSTDKNYRIDFDTRFTGGGRIVPGHEYRNQAHLVEANKDTNVFTRSYFESFRATISYRQGFGGFQVTKASAGSAVPPAGQRFDVTVAYKLPNGKTAADFPGWDAPANPARMTVTVGQTTPSVTFPAGTEITLTEDVATANPAATGITWGDPKFSSEDSRVTIGGDARTATFTVADQTTLPLLLTNNATRTTGESPVPPAPNPGNPDPTDPADPVDPGASDPVDPSESAKAPKTVPTPMRPGLPRTGHEG
>LR134535.1|VEJ59673.1|2849421_2850570_-|Uncharacterised-protein
MRLERSRTSWRRVATVVFVVIATLAAFLVTGTAPAQARINSEIVFTDAVLKHVDQSGNPVTDRQEVWQGDHLELNVNYDGSNTRVAFGDEFTIELPGFLRLQDTTARRPMTTADGTRAGECALNNTGTNSTISCVFKEAVRRKKDVKGSIRVNLQVADTTTAAVAEVRINGRTQTIPMPYDKPVTVKPTVPWQPAGKPSGQAEQLTSNSKGVNWDVTVPGAWLNTNYPSGSRVVMNNTVTPGSFSHDSADWAYSRVIEECADPRNPNTSLSRVVADGIGKSVDGFRLKVDISAQQRSVLTMNGPWSSRCNYHVKLRSLFNDNQTVDKSATYVNITSFENVGEPVTTETRYQETFASTISYRDAGKVMLPSGPVETPLASESA
>LR134535.1|VEJ59672.1|2846646_2849334_-|DNA-topoisomerase-1
MVDKRQRLVIVESPTKATKIAGYLGDGYMVESSRGHIRDLPTGAAEVPARYKGLKWARTGVNIDDNFAPLYVVAADKKATLRELKQKLKAADELLLATDGDREGEAIAWHLMEELKPKVPAHRMVFHEITPSAIAEAVANPRPLDTDLVDAQETRRILDRLYGYEVSPVLWKKVMPKLSAGRVQSVATRLVVDRERERIAFVPAGYWDLDVTLDGGAEADPRTFPARLTSLDGVRVAQGRDFDSTGQPTNTSAVVLDETTATALAAALQAAAFRVDQVEARPYTRRPYEPFRTTTLQQEAGRKLGFTSQRTMSVAQELYEKGFITYMRTDSVTLADSAIAAARDQVEQLFGARYLPPKPRIYASKVKNAQEAHEAIRPAGDVFTHPDATGLSGDAHRLYQLIWMRTLASQMADAKGEQVSVAISAAPTAPVRTGTGTVERAELTASGRTISFHGFLKAYVAGTDDDSTSDDKQSRLPQLTAGQELAAEKVKAAGHETKPPARYTEPSLVAKLEELEIGRPSTYASIIRTITARDYVFKKGSALVPTWLAFAVTRLLEEHFTELVDYTFTAQLEELLDEIAGGRAERLKVLTDFYRGPDGNTAKGLEKLVTELGDIDAKGLSTFPLGDSGIDVRVGRYGTYVEAADGRRANVPDDLPPDGLTAEVAEELLSRPLDEERELGVDPESGRMVVAKNGRFGPYVTEVLPEGTPKSVKPRTASLFKSMSLDSIDLAAAQRLMSLPRVVGKDPEGVEITAQNGRYGPYLKKGSDSRSLTSEEQIFDITLDEALAIYAAPKVRGRAAAAPPLKEFGADPASGKPVVLKSGRFGPYVTDGETNATLRRDDSPETITPERAFELLAEKRAKGPAKKPARKTTTRKKTTTAAKKTTTRKKTTPKA
>LR134535.1|VEJ59671.1|2846430_2846595_+|Uncharacterised-protein
MRRISPNTFLMPSAVTVMGTLTSEGIIAPPGLAEAVMTGRITAHGIEEVPVGVA
>LR134535.1|VEJ59670.1|2845963_2846434_+|NUDIX-domain
MTQTSPARKAVRALVVNGRDELLLIHWEDPLDGHEILEPPGGAVEPDESLEAALLRETAEETGWDIQLCGTPRPHFRKTTWAGQTYEGTEWFCLARPLTAGQQTLETYERPWFRGVKWVPIDHLHVSQIPLEPPHLVSVLKDVMGQSPDSTGGSLS
>LR134535.1|VEJ59669.1|2843408_2845415_-|Kynurenine-3-monooxygenase
MANPDIHIIGAGPVGLAAALLLAAQDRRVTIHEARDAISLTDANSYPIGVNPRGQETLRRIDSRLVEELRAQGELVEGFKIRAGRRMLASMRSGTIIGTTRARLTGILLAAAQQDRRITLSTGHRLEAIDLASRTLQFTGTTTVEVGNGLVIACDGVWSKTRQTMAEQLADFVPEVSDWGIQFRVLFSAPGAMAPGLDPNWHHIFTGKGIYTATLPDGVWCVAVTAIKGDPAEALLLSTEPTEDHINALHRHLRQYAPLVLPLLTRDAYVDFFGRAPFGGAVVRCPRVSHGEWLVLLGDAAHSVIPPTGEGVNSGLEDAMLLADALASGSPMSLREYDEGRIPDLKALGEYACHLKDNIANEDPVRSASNVGLRILSAVAGLVGQKSGELESRLFGPDAGRMPYRDAIGPWIQFRDRWTPPLRRIATGVMRCADKPISAEPQTLVAHQREGARRRISVIGGSSGTGKELAELALKWGFEVTCLSRRGAGPIGARLVSGDARDPEVVRQALKDATAVFVTVNGGSDGSHDRTAITQAVLEAAEQTGLRRIVVQSSLGAGASARMLPPGIRYLATRMLAPALADHTTQEQVVQESGLDWTIVRPVGLTNKRATGMVRELRDAESGWLGWPIPRADVAGHMLRCLDDKSTIQECIAISGRCVLGQHLPSHR
>LR134535.1|VEJ59668.1|2841626_2842949_-|Uncharacterised-protein
MGFERPAVMRFDLPFQADAPSLLSDAIGITGLMERRAASHSIDVTILDTPDDRLLRAGVVLAHRVLGGVGDWYLAASGWVPHLPAERIVPINATAELPQEFADLTRPLVRRAVLGPVAALECQRVEYLLRGPDGPLGSIRDERVTVRRGGMATVRYREATLTPTDLLGRNQLEHVLAALDAVSATAVDEFPSLQQRLGPPATGGTDFPNPGPLNREATMEAFVTRLFAADLQDLVRAQYRDEEAVTDAIQEFRGHVRGLANVLDPEWRQAVESAVEKAATPRQAALDVTESLVAAVRAPRLGDVSAEPAAKLLLKRAQQGAYILADRCRSLTADSSGTDWRAALAAAEQVHACGLVAVQLHGKPGTKLLKTITQVTRDLRDCAADVEPPDLEDLTPAEAFERGRETERCHQKLIAARAGFVADWPERVVKIRKLLAKVRR
>LR134535.1|VEJ59667.1|2841000_2841630_-|Thymidylate-kinase
MTIPETTPGLFVVFEGGDGVGKSTQVAELVTRLQNRRIEPVLTRQPGGTPIGAKLRKLLLDPGHPELTARTEALVYAADKAQHVEEVILPALARGDVVVCDRYVDSMIAYQGAGRVLDLTEVEQVARWATGGLRPDLTVLLDIDPAEAVANIRQQDRLEAAGLEFHRRAREHFLRLAGEDPERYLVLGARESRESIAEKVAEKVFALLG
>LR134535.1|VEJ59677.1|2856737_2857367_-|HTH-type-transcriptional-repressor-KstR
MNMQQPMPAPGTSLRERKKTAKQERILEAATRLFAEKGYEAVTTAEIAEAAEVGVGTLFRYAGSKAELLVAVMNSRFAEGIEAGLSEAAEGRAMAESIIAILRPFVEESMTHPENMLAYEREALFGSVEHREEATSSVSRVEQAILQVMLLHRAKPRDPSADLEDIAHTIYAVLYLDIVKVTTGRSAMADLPARVRRSVDFLTGALLKT
>LR134535.1|VEJ59678.1|2857520_2859173_+|Oleate-hydratase
MIGAGIGNLAAAVYLIRDGGWRGDQITILGLETHGANDGAAVKEFEGEYGHHPLSNAAGFLNRGGRMLNEETYENFWDVMGSVPSLDQPGKSVTQEILDFDHAHPTKDIGRLIDSEGLRVSGPKGYRHMQFTNKQRLLLTRLMMLPESRENELDDVSIRDWFAETPDFFETNFWWMWQTTFAFKDVSSAAELRRYMNRMILEFSRINTLEGVTRTPYNQYESVILPLRAHLQGQGVTFITNRKVTEFVFADTPLRDEIIVTGLRYEEVDNDGTEGLIEVRPEDLVFDTNGSITDSTSIGDLDTAIVEDHRYAPSALLWKQAAGRFYNLGHPDKFFNDRSQSEWTSFTVTTSDHSLINEISRLTRQLPGNALNTFVDSTPLISLVVHHQPHYHAQAPEQGVFWGYALHPRRPGDFIGKPFIEMTGREMLLETIGHLGRIDTTAHPITDRVDELMATVINVVPAHMPYASALFNRRTTLDRPKVVPDGSKNLAFVSQFAEMPFDMVFTEQYSVRCAQVAVYTLLGLDKPLTALHHYERDPRVLAKATRVMFR
>LR134535.1|VEJ59679.1|2859504_2860281_+|Polyphosphate-glucokinase
MNILGIDVGGSGIKGAPVDLTLGDFAEARVRIPTPAKSSPKNVAAVVAEIIENFKEQIPAGSRIGLTVPAPVVHGRVPFMANLHKSWAGFEAATFFEDRLGRPVTLVNDADAAGLAEVHYGAAKGNDGLVIMTTLGTGIGSAIIHRGVLVPNAELGHVELDGFDAETRAASSIKEKEKLSYKEWAVRLQRYYSHIEMLFSPDLFVVGGGVSKDSEKFLPLLQLHTPIVPAKMRNRAGIIGAALAAQDANLHPDSSQAG
>LR134535.1|VEJ59680.1|2860652_2861492_-|Undecaprenyl-diphosphatase
MNWLHAVVLGIVEGITEFLPISSTGHLNIVEKLLGYEINSEGMTAFTAVIQVGAILAAIIYFWKDIVRIVVAWFKGLANKTARQDPDYTLGWGVILGSIPVAVVGLLLKDFIEGPVRSMWVIAGALIVWSAAMWLADRQQNLTKGMQDVSIKDALVIGCFQALSPVFPGISRSGATISAGLFLRFDRVTATRLSFFLGIPALVAAGGLEAITAGKHIADASIGWGPTIVATVVSGMVAYATIAWLLKFVSSNKFTSFLIYRVILGAAIIVLILAGLVAA
>LR134535.1|VEJ59681.1|2861745_2863038_-|enterobactin-exporter-EntS
MVVNNSTSAHGKMPSYSLWGDASYRWWFTADTSGALSKNIALFALPLIALGVTGSEGLAGSFSAILIALQTVFGIAGGVIQDRYDRRFLMVMNGFISATILTAAWMFDLIIGLNLVALAVIALMLGLQAGLLDGTSNAMLRGLVPDEVLPRAMTNNSARDSAVHLASGPTAGILMTLNRVFPLLAGAVLSILGAVTASRIKNYWKRGEAGDASERPGWRDCLGGLKWILRYPFQRRVMLIAVVSAGAGNCFLFLTVLKISNAGSQTLTAGLVNAAAALGMLIGAVSASWVIGRVPSGCIVITMVAVMASGFMVAALAPDIWIQAAAVAVALVPLPAGGAVLTSFFNVLVGKDKLGRVTAAQQLLNFGLLSMLTLIAGWAMQHWGYQAVTVSLAALMLLGMITALFTGALRTMPTPARWGEHISQWELTVF
>LR134535.1|VEJ59682.1|2863333_2864293_-|bile-acid-transporter
MTSHQLNRRFSALMPFVVPSAIVVAVLFPGQFGVLLPAIAPVFFVIVFAGSSTLRARSIVETLRHPLPLLLILGILHVVMPVAAWAVARLGFAGSPDIAAGMVLEFLVPTASAGFAWIAICGGDLTLGLVAVFVDAVLTPVLLPFGVEFLTGAHVSVDSGELMRSMVVMVLAPSVLAVVFNEATGGRVSGRLIPWLQMVVKCGIVVVILASSTRIAPIVRTLDPMLLVITGVMFLISLTGYGFGWLAARLTGQGRAVTVAMIYGSGMRNINAGAVIAAAFFPAATMFPVIISTLFQQVTAALISLAIQRRLPEANPGDD
>LR134535.1|VEJ59683.1|2864765_2865620_+|Fructosamine-3-kinase
MSLPEELIADLDVIRVTPVRGGDIARAYRIDTPSGPVFLKTHPSPTRMLFEREAHGLRALREAAPPELRVPEVLAASPRGLVLEWIDEGGRGPATESALGVGLARLHSLPAPHFGGLDGDTSGYLGSVEVDLTPASSWSEFYLERRVLPLTRRAVTEKRVPAEALRLLDVLSSRIDELCGPPEPPSLVHGDLWAGNRLVDVTGVNWLIDPAAHYAHREFDLAMMALFGGFGAEAFASYDEAHPLADGWQERIPWHQLTPLLVHAILFGGGYGTSVLSTLRRLAA
>LR134535.1|VEJ59684.1|2866007_2867576_+|Levanase-precursor
MTSGKYGRRALLFGIGTTAGALALGSRIWDDATAFPPSSTPSAPTASGSPSPAPDDPFRPVYHYTPASGNLADPNGLILHQGEYHLFHQQDGTWAHAVSSDMVHWERLGTALGHDALGLAMSGSCVDDGTNTSGMVPGGGMVAIYTSTKGGEAQSLAYSTDRGRSWKRYDGNPVIPNEGRKDFRDPKVFWHEPTRSWVMVVSLGDRIAVYRSGDLRSWTHASDFGEGKGSHAAVWECPDLFPLDDVSTGQTRWVLTTSVGDNAETHGSTAQHFIGDFDGFTFFPEDDRVRFTDAGQDFYAAQTFEKVEGRRIWLGWMGNWAYPYSMPTKGWKNQMSIPRELTLTTRDGVRVLQQQPVRELNALRGRATDVGGLSATDTTTGLGAGRVVELDLTLDVSKASDAWLGLCRGQVDGTLQEVRVGVLPGEGIFYLDRTAGGLATVPGRDGGTAQFALRREVAYRPVDGKVRLHVHVDNSSVEVFVDDGAPVGSFLVFNDPRAQELVLGAKGTAKVISGAVTPLSLQ
>LR134535.1|VEJ59685.1|2867766_2868396_-|Lipoprotein-releasing-system-ATP-binding-protein-LolD
MSVLALEKVNYAYEKMARKLLENVTIEFEGGKFYAILGGSGAGKSTLLGLLAGLDVPTSGKILCNGKDISEEGLPKHRKRNVSLVFQNYNLIDYLTPLENLRLVNHRADAGVLEKMGLEKEEINRNVMKLSGGQQQRVAIGRALVSDAPVILADEPTGNLDEDTASDIIDILKTAAHDKGKCVIVVTHSKQVAKAADIVLRLRNRKLVA
>LR134535.1|VEJ59686.1|2868407_2869655_-|acidobacterial-duplicated-orphan-permease
MSLLLKRAWLSVSRRIGKSVVLLLIMTVIFTALVAEASVRSSMQALRESVSRGVPAGFVVRPGSGELSLTDAQSVSGVQGVTGHNYVRGLTATPSDLKLVEMPASGVELSGDVAPEAGVTGVTRSDLIHGFAAKQYTLVEGRHIAEGDQNSAIMHQELAAKNGLKVGDRVTLNRDGKSVTVTIVGLFTGTSGKASLPSEMAENTFYTDLASSGELAAGQGLTEAQYLVSSADELGAAIARAKGLSLPWDNLQVEDNAKTFSGVLSGIATVEGLLNLMLAGVSLASVAILVFVLVFWVRGRVHEIGILLSVGTSKKRLLVQFLIELTLVALAAGGLAALASDQVSRMLGDLVVGQATGAEDGQSGVNVPPPKFAAASAFDFGRAWLLGYAVVLLSAVVAMIPMLRLKPKQILSKMS

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Crispr_ID: LR134535_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134535_9

2899971-2909769

TypeI-A

Consensus_repeat	Method
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CRISPRCasFinder
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CRT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	PILER-CR
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	PILER-CR

133 spacers

csa3,cas2,cas1,csb2gr5,cas7,cas8u1,cas3

The CRISPR arrays of LR134535_9

>merge|LR134535|9|2899971-2909769|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
GCCTCAATGGAGTCCGACCTAGAAGGCTGGAACAATCATGACAATTCCGCCGGAGGGGTCGATGACGGCATACACGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATAACACCTACGCTGACAAGACCATCTACAACTTCACCGAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGATCGAGGACCGGCAGCGCTTCCTCCCAACCCTTCGTGTCTCAATGAAGTCCGGCCTAGAAGGCCAGAACAATGCACAAACCGAAGCCGAAGCCAGTTAAGCGACCAGGTGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCGGGCTAGTGGTGAATGGGCTTCGCGCGATCCGCGAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCAATTCCATGTCGCTGGCCTGCCGAAACCCCAAGGGTCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCGAGCTCGCGGAGGAGAACAGGCGGGCCATCAAAGAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCTTTCGACGGGTCCGCGAGGTGTTGCAGCATCGTCTTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCTAGGGGGAGTGATGTCCGCACCATGCTGGCGAATCTGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCAGCTGTGGCAGTAACCACCCCCCTGGACCTGCTCGTCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTAACATCCTTCATTTTGAAAAAAGGGGATAAAAATAATGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATACGAGGATGAGGCGTGGCCTCATGTCGAGACCTTGGCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCAGGTACGCCAGCGGATGGTACCCATCCACGGGGAACTCGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATAATTGGGGTCTATCGTAATTGAACAGTCCCAAGGAATGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATAGCGATGACGGCAGGAAGGAGTGAGCGTGGGCCGCAAGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCCGAGAGGACTGCCTTCGCCCCCTGGGAGGGGGTATCGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCTGGACGAACCGCACCCCCAGCACCCTCGTTTGAAGAACGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATACCTTCGCGGATGCCGCAGCGATCGCGGTACTCGGGTCGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATGCCGCCGCATGACCGCCATCACCCTAACGGGGAATCTGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATGCAACGCGGTGTTCGCAGATTCCTGAACACCGTAACCGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCACTACCGAGTTTTCCACATTGGTGACCTCACGGAGGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATGGCAGCAATCCACCGAGCGGTGTCGCTCTCCGTACCTTGAGGTCTCAATGAAGCCCGGCCTGGAAGACCGGAACAATCAGGAGATTCCCGTTCTACTGCAAGCTCAGCCCCAATGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATGCTGCAGCCGCCCGGACTGCCCGGGGTGCGTGTGGCATGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATTATGCGGAACCCGTACAAGGTCCCTAAGTATCTTCAAAAGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCACACCGGAAGGTGCGCTGTGAACGGTGTCGACGACATCGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATAAACTCGTCTACCTGTCCGAGAAGTACAATCCACTGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCAGTGTTCAAAACTATTGAATTGACCGTCAAGGGTCAGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCGGAGGCGCACCGTGATCATGTGCACGCGTACTTCGGTGGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCAGAGGACGCCATTGAGGGGCTCTGCTACCGCGGTGACGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATATGGGTTTCAGGACACTGTTCCACACTGCCGTCACGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCATGGAAATTCTGTGCGAGCCGTACTGGCTCAAGAAGTGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCCCGACCCCCTCATGGGGACAACCGACTGCCGACACTGGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATATGCCACCTTCACCGGCCGACATTGTTCGGGGTGTGTGGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCGGATCCTGCTTGAAACGGCGGCCGTAATTCAACGGTCTCAATGAAGTCTGGCCTGGAAGACCGGAACAATATAGCATGCGGACTTGTTCATCGGTCAGCTGATTAATTTGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATGCAGCCATCCGCTCTTCCCGGTATCGCCGCAGATAGATGTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAATCTGGAACAATACCGCAATGGACATAAACTACTGTTAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGCGGCTCACCAACCTCTACGCCACCTACGGGCAGCTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGGCCACCGCGCCCAGCGGCGCGGCGGCGAGCAGGGCGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGTTCGGTCTTCCTCTGAGGCGGCCAGGCTCCGTCGTCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCGATCTGGGCCACAGACTCCCACATTAGTAGCTTTCGTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTGGGCCGATGAGGACAAGTTCATCCTCGAGCTGTTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGGTGCTTGTGGAGTTCCGCGGACACTTGGTCTATGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGGATGCTAATTCGCTTGAACAGCGCGCAGAAAGGCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGATGACGGCTTGTTCTTCGAGGTTGCCTGTTTCCCTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTCGACAACGGTGATGCGCTGTGGCGGGTCATCTGGGGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTCGAACAATTCCCACGCGGCCGCCTCAACGACGTTCTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCAAAGTGTTCCGAGCTATTGCCTTCATGGCGGTAGCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCTGATATCGCGTATCCGCAAATACGACCCCGTCGGATAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCGGCAATTATCGGAATGGTCAACGCAATCAAGAAGCTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTCTGCCCATGCAAAGTATCTGGACTTCATTGAAGAAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCATGATGGCGATACCGAGGATGTAGAGGCTGTGGATGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCACCCTCGACATCGTGGTTCACGGGGAGGTATTGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAGGACTTCCTCATCGAGTTGCTCCGCGACAACCTCCTGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATATGACAAAGTGCGGGAATTGATTCATGAAACAAAGATTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTATACTAGTAGACATCAGGGCGGGAGGCCCTGAGGAAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGTAGTACAGATCCACCAACTGACGGTACACCATCCACGTCTCAATGAAGTCCGGCCTGGAAGGCCGGAACAATCAGAACACCTGATTGATTCTGAAGGCCCCAAAGGGCTGTCTAAATGAAGTCCGGCCTAGAAGGCCGGAACAATTCGGCTTGCTCAGGCCACCGCCAGGCTCGCCCCTCATGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCACGGTGGACTCCACACGAATACCCCCGCGCTTGTAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCTATTACCAAACCCGGACGTATCTTGAAAGCCGCATCAAAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGGCGCTGACGGTCATTATGGCCATTCGCACATTTCTATGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTGCCTCGGTGAAATCCGAGAGACTCTCGAGGCCTGCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTGAGATTCAGAAGCTGACCAACCCTGCGGTCAGGAAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAAAATGCTCAGGCCATTGCCGAGGTGAAAGAAGCTCAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTGAGATTCAGAAGCTGACCAACCCTGCGGTCAGGAAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAAGGGCAACGAGGCCGCCGCGCTGGAATTGGCATCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCGCGCTGCTCGCGTTCGCCGTCCACGACCCCGAGTGCGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGTCGTGTGGAGGCCACTTATGCTCTTCCTGCCGTCATGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCAAAGGTCTTGTTACGCTTGCCAAGAAGGGCGAGGATCCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTTGTCTGGTTCCTTATGTGGATGCTTCCGGGAATGTAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTCGCCTGCGAAATGGCGCTACGGGAAGTCGGCGTCGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAGGTTTTTGGGCGGGCCTATCAATATCACAAGACCGGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGCCTGGCCCTGTGGGATTACTCCTGGGGCCGGCTAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCGAGAGTCACAAAATTAAATCGTGCTCGAGTAAAGCTGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTCGGCGGCCTGGATGCGGGCTGCGAAGAGGCTGGTGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCGAGTGGGCCTACCAAGAAGTGTGCGGGAGACCCATGTCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGGGCACTTGTCGCCGAGGTGGGTGGGGAAGTTGATGTCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCAGCGAAGCCGTCGGACTGGATCCTAAGCAGGCTATTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAGGTTCGTAAAGAATTCGACCTCCGCCTCGATGAAATCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAAACCCGCTACCTGACGCGCGGGGAGGGCGACTCCCTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTTGCGATTATCGGTCAAGATCAAGAATTGACCTACAAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTTCCTGTCGAAGCAGAGCCCCGCCCTGGCGAAAAAGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATACGACTGGCAGGGCCACGTAATCGCGGCGTACTGCGAAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGCCACTGAAAGTGAGGTAAAACATGAGTAAACGACAATTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGGGCCGTCTACTGGCAGTGCCGCGCGTGCCTCGAACTCGAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCGCGGCAGTGCTGCGGGGCTCCACGCGGGAAGAACTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAAGTCGCAGGTCATGGTGGGGATGGTGTTGATGCCGGCGTGGGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCACACCGGCGTCATCTCGGTAAACATACGAGACGACCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCATTGACTTCGCACGCTGTGACGGTTGGATCAACACGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATATGCAGGAAGTAATTCCAATACAGGCCCTTCGGATTCTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTCCGTCGAAGGATCGGACGGATCCGCGACGAGGTTAGTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGTCACCTCGCCCGCCACGGCATCACCCCCACCAGTCCCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCTCCACTTCGAGGTTCGGTCGAAATCGATCGCGAAGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGATTACGAGGATCTTGGCGGCAAGGAGCGCGCCCCCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGGTCAAGAAAGGTATCGGAGAAGTAAACGAGATAATTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTCCCGCCGACATTGCACGCGGGGTCTGGCGGTACTGGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCGCATACCGCACAGCCCGGAGCGACGGGCAGAGTTTCGAGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGACCTTCCTCATAAAGCGTATGACTATTCCTTAAGATGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCAAGGGTTCGAACATTGATCTGCACTCGACGGAGCGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGAACGCGGGGCCTTTCGTGAACTTCGGGCCAGAGTTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATATACGTCGTCTACCGTGATGTGAAGATTGGGGATCCTGAGACGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGGTTGCATCCATGACTGCTACCACGGGGGTGCCTTCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCATCAACCCGTCAAACCGACGCCGTCCTCACCGAACTAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATATCCCATGACTCATGCAAAATATGGAGGTATCTACTTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTGGTAACGCCATGGCCTCAGTTGGGACACTGTGGATGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGCCCCATGAGTAAACTTGACGAGCGCATAGTCTCGATGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCTCACGTCGAAGTTGAAGCCCACTGGCGAGACAGCAGCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATATGTAAGGTATGAGTGGGTTCAATTCGATGATTTCATGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCGAACGGGAGGTGGATTTCGATTGAGCGCCAAGATCAAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGCATGTTCACAAGGACGGTGTGTTGCTGGAAGCTCTGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATACGACGGAGCAGCAGAAAGCAACGGTGGAGATCGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGAGGCTGACCATCTGGTTTGGTATTCATTGGTATATCAGTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCAGCAACAACCGAACCACCCAGCCATCGACCCTGCTCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAGTGTATTCCTGGCTGGGGAAGAAAACAAACATAGAGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCAAGCCATTCTTGGAGTTCATCCAACTCGGCTTCTGGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCTCGCAGCCGCGTCGCCGTCGACTCCTCCGCGGAGGGCGAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCTCAGCCGAAAGCTCAACGGCCACACCTCCTTCCTGGTCGTCTCAATGAGGTCCGGCCTAGAAGGCCGGAACAATCCGCAGTCAGGGATGTAGGTGCGCCACACCTTGAAGTCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCTCGCCGATATCCCGAACATTTGTGTCGCCTATAGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGCCGCGAAGCGGCGCTGGACGAGCTCAACGTCCACTTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGCTTGCGACAGTGGCGAGACCGCCGGCGACGAGGAAAGCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCAATCAAGATCCAGGCCTCCGCCACCTTGGTGGAAGGCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGCCATCCCCGGATTCAGGCCCGATGAACCCGACCAGGCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGACGCGGGCGGCGACAACGTCCACGAGTACAAGTCCCTGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATATCCCCCCACATCCGCGAGATCCAGCCCGAACCCGAACCGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAGATTACGTCATGGAGCAGACCGATATCCTGTAAGGGGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATTTGTGCTGTCCAAAGGTGCTCTGACTGAGGACCAATTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCGACGTCATCACGTTCTTCCGGAACCTACCCGGCCAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCACTTGGATAAGAATCTCAATGGAATCCCGGATTCCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGGAGGAGGCCTGGGCGGTCCTGGCCCGCATATCCGGAGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATGGGGTCTGCGTACGCAAGCCCGGCCGATCCACCAACCGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT

>LR134535|9|9|2899971-2909769|CRISPRCasFinder
GCCTCAATGGAGTCCGACCTAGAAGGCTGGAACAAT	CATGACAATTCCGCCGGAGGGGTCGATGACGGCATACAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AACACCTACGCTGACAAGACCATCTACAACTTCACCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATCGAGGACCGGCAGCGCTTCCTCCCAACCCTTCGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCAGAACAAT	GCACAAACCGAAGCCGAAGCCAGTTAAGCGACCAGGTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGGGCTAGTGGTGAATGGGCTTCGCGCGATCCGCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAATTCCATGTCGCTGGCCTGCCGAAACCCCAAGGGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAGCTCGCGGAGGAGAACAGGCGGGCCATCAAAGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTTTCGACGGGTCCGCGAGGTGTTGCAGCATCGTCTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTAGGGGGAGTGATGTCCGCACCATGCTGGCGAATCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGCTGTGGCAGTAACCACCCCCCTGGACCTGCTCGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TAACATCCTTCATTTTGAAAAAAGGGGATAAAAATAAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGAGGATGAGGCGTGGCCTCATGTCGAGACCTTGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGGTACGCCAGCGGATGGTACCCATCCACGGGGAACTC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AATTGGGGTCTATCGTAATTGAACAGTCCCAAGGAAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AGCGATGACGGCAGGAAGGAGTGAGCGTGGGCCGCAA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CCGAGAGGACTGCCTTCGCCCCCTGGGAGGGGGTATC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CTGGACGAACCGCACCCCCAGCACCCTCGTTTGAAGAAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ACCTTCGCGGATGCCGCAGCGATCGCGGTACTCGGGTC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCCGCCGCATGACCGCCATCACCCTAACGGGGAATCT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCAACGCGGTGTTCGCAGATTCCTGAACACCGTAACC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CACTACCGAGTTTTCCACATTGGTGACCTCACGGAG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GGCAGCAATCCACCGAGCGGTGTCGCTCTCCGTACCTTGAG
GTCTCAATGAAGCCCGGCCTGGAAGACCGGAACAAT	CAGGAGATTCCCGTTCTACTGCAAGCTCAGCCCCAAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCTGCAGCCGCCCGGACTGCCCGGGGTGCGTGTGGCAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	TATGCGGAACCCGTACAAGGTCCCTAAGTATCTTCAAAA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CACACCGGAAGGTGCGCTGTGAACGGTGTCGACGACATC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AAACTCGTCTACCTGTCCGAGAAGTACAATCCACT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CAGTGTTCAAAACTATTGAATTGACCGTCAAGGGTCA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CGGAGGCGCACCGTGATCATGTGCACGCGTACTTCGGTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CAGAGGACGCCATTGAGGGGCTCTGCTACCGCGGTGAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ATGGGTTTCAGGACACTGTTCCACACTGCCGTCAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CATGGAAATTCTGTGCGAGCCGTACTGGCTCAAGAAGT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CCCGACCCCCTCATGGGGACAACCGACTGCCGACACTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ATGCCACCTTCACCGGCCGACATTGTTCGGGGTGTGTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CGGATCCTGCTTGAAACGGCGGCCGTAATTCAACG
GTCTCAATGAAGTCTGGCCTGGAAGACCGGAACAAT	ATAGCATGCGGACTTGTTCATCGGTCAGCTGATTAATTT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCAGCCATCCGCTCTTCCCGGTATCGCCGCAGATAGAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CTGGAACAATACCGCAATGGACATAAACTACTGTTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCGGCTCACCAACCTCTACGCCACCTACGGGCAGCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGCCACCGCGCCCAGCGGCGCGGCGGCGAGCAGGGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTTCGGTCTTCCTCTGAGGCGGCCAGGCTCCGTCGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGATCTGGGCCACAGACTCCCACATTAGTAGCTTTCGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGGGCCGATGAGGACAAGTTCATCCTCGAGCTGTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTGCTTGTGGAGTTCCGCGGACACTTGGTCTATG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGATGCTAATTCGCTTGAACAGCGCGCAGAAAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATGACGGCTTGTTCTTCGAGGTTGCCTGTTTCCCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGACAACGGTGATGCGCTGTGGCGGGTCATCTGGGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGAACAATTCCCACGCGGCCGCCTCAACGACGTTCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAAAGTGTTCCGAGCTATTGCCTTCATGGCGGTAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTGATATCGCGTATCCGCAAATACGACCCCGTCGGATA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGGCAATTATCGGAATGGTCAACGCAATCAAGAAGCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCTGCCCATGCAAAGTATCTGGACTTCATTGAAGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATGATGGCGATACCGAGGATGTAGAGGCTGTGGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCACCCTCGACATCGTGGTTCACGGGGAGGTATTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGACTTCCTCATCGAGTTGCTCCGCGACAACCTCCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGACAAAGTGCGGGAATTGATTCATGAAACAAAGATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TATACTAGTAGACATCAGGGCGGGAGGCCCTGAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTAGTACAGATCCACCAACTGACGGTACACCATCCAC
GTCTCAATGAAGTCCGGCCTGGAAGGCCGGAACAAT	CAGAACACCTGATTGATTCTGAAGGCCCCAAAGGGCT
GTCTAAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGGCTTGCTCAGGCCACCGCCAGGCTCGCCCCTCAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACGGTGGACTCCACACGAATACCCCCGCGCTTGTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTATTACCAAACCCGGACGTATCTTGAAAGCCGCATCAAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGCGCTGACGGTCATTATGGCCATTCGCACATTTCTAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGCCTCGGTGAAATCCGAGAGACTCTCGAGGCCTGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGAGATTCAGAAGCTGACCAACCCTGCGGTCAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAAATGCTCAGGCCATTGCCGAGGTGAAAGAAGCTCA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGAGATTCAGAAGCTGACCAACCCTGCGGTCAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAGGGCAACGAGGCCGCCGCGCTGGAATTGGCATC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGCGCTGCTCGCGTTCGCCGTCCACGACCCCGAGTGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTCGTGTGGAGGCCACTTATGCTCTTCCTGCCGTCATG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAAAGGTCTTGTTACGCTTGCCAAGAAGGGCGAGGATCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGTCTGGTTCCTTATGTGGATGCTTCCGGGAATGTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGCCTGCGAAATGGCGCTACGGGAAGTCGGCGTCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGTTTTTGGGCGGGCCTATCAATATCACAAGACCGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCTGGCCCTGTGGGATTACTCCTGGGGCCGGCTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAGAGTCACAAAATTAAATCGTGCTCGAGTAAAGCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGGCGGCCTGGATGCGGGCTGCGAAGAGGCTGGTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGAGTGGGCCTACCAAGAAGTGTGCGGGAGACCCATGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGCACTTGTCGCCGAGGTGGGTGGGGAAGTTGATGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGCGAAGCCGTCGGACTGGATCCTAAGCAGGCTATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGTTCGTAAAGAATTCGACCTCCGCCTCGATGAAATC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAACCCGCTACCTGACGCGCGGGGAGGGCGACTCCCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGCGATTATCGGTCAAGATCAAGAATTGACCTACAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTCCTGTCGAAGCAGAGCCCCGCCCTGGCGAAAAAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGACTGGCAGGGCCACGTAATCGCGGCGTACTGCGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCACTGAAAGTGAGGTAAAACATGAGTAAACGACAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGCCGTCTACTGGCAGTGCCGCGCGTGCCTCGAACTCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGCGGCAGTGCTGCGGGGCTCCACGCGGGAAGAACT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAGTCGCAGGTCATGGTGGGGATGGTGTTGATGCCGGCGTGGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACACCGGCGTCATCTCGGTAAACATACGAGACGACC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATTGACTTCGCACGCTGTGACGGTTGGATCAACACG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGCAGGAAGTAATTCCAATACAGGCCCTTCGGATTCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCCGTCGAAGGATCGGACGGATCCGCGACGAGGTTAGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTCACCTCGCCCGCCACGGCATCACCCCCACCAGTCCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCCACTTCGAGGTTCGGTCGAAATCGATCGCGAAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATTACGAGGATCTTGGCGGCAAGGAGCGCGCCCCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTCAAGAAAGGTATCGGAGAAGTAAACGAGATAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCCCGCCGACATTGCACGCGGGGTCTGGCGGTACTGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGCATACCGCACAGCCCGGAGCGACGGGCAGAGTTTCGAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GACCTTCCTCATAAAGCGTATGACTATTCCTTAAGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAAGGGTTCGAACATTGATCTGCACTCGACGGAGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GAACGCGGGGCCTTTCGTGAACTTCGGGCCAGAGTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATACGTCGTCTACCGTGATGTGAAGATTGGGGATCCTGAGAC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTTGCATCCATGACTGCTACCACGGGGGTGCCTTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATCAACCCGTCAAACCGACGCCGTCCTCACCGAACTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATCCCATGACTCATGCAAAATATGGAGGTATCTACTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGGTAACGCCATGGCCTCAGTTGGGACACTGTGGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCCCATGAGTAAACTTGACGAGCGCATAGTCTCGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCACGTCGAAGTTGAAGCCCACTGGCGAGACAGCAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGTAAGGTATGAGTGGGTTCAATTCGATGATTTCAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAACGGGAGGTGGATTTCGATTGAGCGCCAAGATCAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCATGTTCACAAGGACGGTGTGTTGCTGGAAGCTCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGACGGAGCAGCAGAAAGCAACGGTGGAGATCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GAGGCTGACCATCTGGTTTGGTATTCATTGGTATATCAGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAGCAACAACCGAACCACCCAGCCATCGACCCTGCTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGTGTATTCCTGGCTGGGGAAGAAAACAAACATAGAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAAGCCATTCTTGGAGTTCATCCAACTCGGCTTCTGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCGCAGCCGCGTCGCCGTCGACTCCTCCGCGGAGGGCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCAGCCGAAAGCTCAACGGCCACACCTCCTTCCTGGTC
GTCTCAATGAGGTCCGGCCTAGAAGGCCGGAACAAT	CCGCAGTCAGGGATGTAGGTGCGCCACACCTTGAAGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCTCGCCGATATCCCGAACATTTGTGTCGCCTATAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCGCGAAGCGGCGCTGGACGAGCTCAACGTCCACTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCTTGCGACAGTGGCGAGACCGCCGGCGACGAGGAAAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAATCAAGATCCAGGCCTCCGCCACCTTGGTGGAAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCATCCCCGGATTCAGGCCCGATGAACCCGACCAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GACGCGGGCGGCGACAACGTCCACGAGTACAAGTCCCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATCCCCCCACATCCGCGAGATCCAGCCCGAACCCGAACCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGATTACGTCATGGAGCAGACCGATATCCTGTAAGGGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGTGCTGTCCAAAGGTGCTCTGACTGAGGACCAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGACGTCATCACGTTCTTCCGGAACCTACCCGGCCA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACTTGGATAAGAATCTCAATGGAATCCCGGATTCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGAGGAGGCCTGGGCGGTCCTGGCCCGCATATCCGGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGGTCTGCGTACGCAAGCCCGGCCGATCCACCAACC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT

>LR134535|9|4|2899971-2909769|CRT
GCCTCAATGGAGTCCGACCTAGAAGGCTGGAACAAT	CATGACAATTCCGCCGGAGGGGTCGATGACGGCATACAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AACACCTACGCTGACAAGACCATCTACAACTTCACCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATCGAGGACCGGCAGCGCTTCCTCCCAACCCTTCGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCAGAACAAT	GCACAAACCGAAGCCGAAGCCAGTTAAGCGACCAGGTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGGGCTAGTGGTGAATGGGCTTCGCGCGATCCGCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAATTCCATGTCGCTGGCCTGCCGAAACCCCAAGGGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAGCTCGCGGAGGAGAACAGGCGGGCCATCAAAGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTTTCGACGGGTCCGCGAGGTGTTGCAGCATCGTCTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTAGGGGGAGTGATGTCCGCACCATGCTGGCGAATCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGCTGTGGCAGTAACCACCCCCCTGGACCTGCTCGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TAACATCCTTCATTTTGAAAAAAGGGGATAAAAATAAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGAGGATGAGGCGTGGCCTCATGTCGAGACCTTGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGGTACGCCAGCGGATGGTACCCATCCACGGGGAACTC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AATTGGGGTCTATCGTAATTGAACAGTCCCAAGGAAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AGCGATGACGGCAGGAAGGAGTGAGCGTGGGCCGCAA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CCGAGAGGACTGCCTTCGCCCCCTGGGAGGGGGTATC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CTGGACGAACCGCACCCCCAGCACCCTCGTTTGAAGAAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ACCTTCGCGGATGCCGCAGCGATCGCGGTACTCGGGTC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCCGCCGCATGACCGCCATCACCCTAACGGGGAATCT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCAACGCGGTGTTCGCAGATTCCTGAACACCGTAACC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CACTACCGAGTTTTCCACATTGGTGACCTCACGGAG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GGCAGCAATCCACCGAGCGGTGTCGCTCTCCGTACCTTGAG
GTCTCAATGAAGCCCGGCCTGGAAGACCGGAACAAT	CAGGAGATTCCCGTTCTACTGCAAGCTCAGCCCCAAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCTGCAGCCGCCCGGACTGCCCGGGGTGCGTGTGGCAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	TATGCGGAACCCGTACAAGGTCCCTAAGTATCTTCAAAA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CACACCGGAAGGTGCGCTGTGAACGGTGTCGACGACATC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AAACTCGTCTACCTGTCCGAGAAGTACAATCCACT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CAGTGTTCAAAACTATTGAATTGACCGTCAAGGGTCA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CGGAGGCGCACCGTGATCATGTGCACGCGTACTTCGGTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CAGAGGACGCCATTGAGGGGCTCTGCTACCGCGGTGAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ATGGGTTTCAGGACACTGTTCCACACTGCCGTCAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CATGGAAATTCTGTGCGAGCCGTACTGGCTCAAGAAGT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CCCGACCCCCTCATGGGGACAACCGACTGCCGACACTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ATGCCACCTTCACCGGCCGACATTGTTCGGGGTGTGTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CGGATCCTGCTTGAAACGGCGGCCGTAATTCAACG
GTCTCAATGAAGTCTGGCCTGGAAGACCGGAACAAT	ATAGCATGCGGACTTGTTCATCGGTCAGCTGATTAATTT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCAGCCATCCGCTCTTCCCGGTATCGCCGCAGATAGAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CTGGAACAATACCGCAATGGACATAAACTACTGTTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCGGCTCACCAACCTCTACGCCACCTACGGGCAGCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGCCACCGCGCCCAGCGGCGCGGCGGCGAGCAGGGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTTCGGTCTTCCTCTGAGGCGGCCAGGCTCCGTCGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGATCTGGGCCACAGACTCCCACATTAGTAGCTTTCGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGGGCCGATGAGGACAAGTTCATCCTCGAGCTGTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTGCTTGTGGAGTTCCGCGGACACTTGGTCTATG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGATGCTAATTCGCTTGAACAGCGCGCAGAAAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATGACGGCTTGTTCTTCGAGGTTGCCTGTTTCCCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGACAACGGTGATGCGCTGTGGCGGGTCATCTGGGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGAACAATTCCCACGCGGCCGCCTCAACGACGTTCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAAAGTGTTCCGAGCTATTGCCTTCATGGCGGTAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTGATATCGCGTATCCGCAAATACGACCCCGTCGGATA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGGCAATTATCGGAATGGTCAACGCAATCAAGAAGCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCTGCCCATGCAAAGTATCTGGACTTCATTGAAGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATGATGGCGATACCGAGGATGTAGAGGCTGTGGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCACCCTCGACATCGTGGTTCACGGGGAGGTATTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGACTTCCTCATCGAGTTGCTCCGCGACAACCTCCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGACAAAGTGCGGGAATTGATTCATGAAACAAAGATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TATACTAGTAGACATCAGGGCGGGAGGCCCTGAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTAGTACAGATCCACCAACTGACGGTACACCATCCAC
GTCTCAATGAAGTCCGGCCTGGAAGGCCGGAACAAT	CAGAACACCTGATTGATTCTGAAGGCCCCAAAGGGCT
GTCTAAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGGCTTGCTCAGGCCACCGCCAGGCTCGCCCCTCAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACGGTGGACTCCACACGAATACCCCCGCGCTTGTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTATTACCAAACCCGGACGTATCTTGAAAGCCGCATCAAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGCGCTGACGGTCATTATGGCCATTCGCACATTTCTAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGCCTCGGTGAAATCCGAGAGACTCTCGAGGCCTGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGAGATTCAGAAGCTGACCAACCCTGCGGTCAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAAATGCTCAGGCCATTGCCGAGGTGAAAGAAGCTCA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGAGATTCAGAAGCTGACCAACCCTGCGGTCAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAGGGCAACGAGGCCGCCGCGCTGGAATTGGCATC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGCGCTGCTCGCGTTCGCCGTCCACGACCCCGAGTGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTCGTGTGGAGGCCACTTATGCTCTTCCTGCCGTCATG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAAAGGTCTTGTTACGCTTGCCAAGAAGGGCGAGGATCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGTCTGGTTCCTTATGTGGATGCTTCCGGGAATGTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGCCTGCGAAATGGCGCTACGGGAAGTCGGCGTCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGTTTTTGGGCGGGCCTATCAATATCACAAGACCGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCTGGCCCTGTGGGATTACTCCTGGGGCCGGCTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAGAGTCACAAAATTAAATCGTGCTCGAGTAAAGCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGGCGGCCTGGATGCGGGCTGCGAAGAGGCTGGTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGAGTGGGCCTACCAAGAAGTGTGCGGGAGACCCATGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGCACTTGTCGCCGAGGTGGGTGGGGAAGTTGATGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGCGAAGCCGTCGGACTGGATCCTAAGCAGGCTATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGTTCGTAAAGAATTCGACCTCCGCCTCGATGAAATC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAACCCGCTACCTGACGCGCGGGGAGGGCGACTCCCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGCGATTATCGGTCAAGATCAAGAATTGACCTACAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTCCTGTCGAAGCAGAGCCCCGCCCTGGCGAAAAAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGACTGGCAGGGCCACGTAATCGCGGCGTACTGCGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCACTGAAAGTGAGGTAAAACATGAGTAAACGACAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGCCGTCTACTGGCAGTGCCGCGCGTGCCTCGAACTCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGCGGCAGTGCTGCGGGGCTCCACGCGGGAAGAACT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAGTCGCAGGTCATGGTGGGGATGGTGTTGATGCCGGCGTGGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACACCGGCGTCATCTCGGTAAACATACGAGACGACC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATTGACTTCGCACGCTGTGACGGTTGGATCAACACG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGCAGGAAGTAATTCCAATACAGGCCCTTCGGATTCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCCGTCGAAGGATCGGACGGATCCGCGACGAGGTTAGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTCACCTCGCCCGCCACGGCATCACCCCCACCAGTCCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCCACTTCGAGGTTCGGTCGAAATCGATCGCGAAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATTACGAGGATCTTGGCGGCAAGGAGCGCGCCCCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTCAAGAAAGGTATCGGAGAAGTAAACGAGATAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCCCGCCGACATTGCACGCGGGGTCTGGCGGTACTGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGCATACCGCACAGCCCGGAGCGACGGGCAGAGTTTCGAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GACCTTCCTCATAAAGCGTATGACTATTCCTTAAGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAAGGGTTCGAACATTGATCTGCACTCGACGGAGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GAACGCGGGGCCTTTCGTGAACTTCGGGCCAGAGTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATACGTCGTCTACCGTGATGTGAAGATTGGGGATCCTGAGAC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTTGCATCCATGACTGCTACCACGGGGGTGCCTTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATCAACCCGTCAAACCGACGCCGTCCTCACCGAACTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATCCCATGACTCATGCAAAATATGGAGGTATCTACTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGGTAACGCCATGGCCTCAGTTGGGACACTGTGGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCCCATGAGTAAACTTGACGAGCGCATAGTCTCGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCACGTCGAAGTTGAAGCCCACTGGCGAGACAGCAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGTAAGGTATGAGTGGGTTCAATTCGATGATTTCAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAACGGGAGGTGGATTTCGATTGAGCGCCAAGATCAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCATGTTCACAAGGACGGTGTGTTGCTGGAAGCTCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGACGGAGCAGCAGAAAGCAACGGTGGAGATCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GAGGCTGACCATCTGGTTTGGTATTCATTGGTATATCAGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAGCAACAACCGAACCACCCAGCCATCGACCCTGCTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGTGTATTCCTGGCTGGGGAAGAAAACAAACATAGAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAAGCCATTCTTGGAGTTCATCCAACTCGGCTTCTGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCGCAGCCGCGTCGCCGTCGACTCCTCCGCGGAGGGCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCAGCCGAAAGCTCAACGGCCACACCTCCTTCCTGGTC
GTCTCAATGAGGTCCGGCCTAGAAGGCCGGAACAAT	CCGCAGTCAGGGATGTAGGTGCGCCACACCTTGAAGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCTCGCCGATATCCCGAACATTTGTGTCGCCTATAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCGCGAAGCGGCGCTGGACGAGCTCAACGTCCACTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCTTGCGACAGTGGCGAGACCGCCGGCGACGAGGAAAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAATCAAGATCCAGGCCTCCGCCACCTTGGTGGAAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCATCCCCGGATTCAGGCCCGATGAACCCGACCAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GACGCGGGCGGCGACAACGTCCACGAGTACAAGTCCCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATCCCCCCACATCCGCGAGATCCAGCCCGAACCCGAACCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGATTACGTCATGGAGCAGACCGATATCCTGTAAGGGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGTGCTGTCCAAAGGTGCTCTGACTGAGGACCAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGACGTCATCACGTTCTTCCGGAACCTACCCGGCCA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACTTGGATAAGAATCTCAATGGAATCCCGGATTCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGAGGAGGCCTGGGCGGTCCTGGCCCGCATATCCGGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGGTCTGCGTACGCAAGCCCGGCCGATCCACCAACC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT

>LR134535|9|4|2900046-2906381|PILER-CR
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AACACCTACGCTGACAAGACCATCTACAACTTCACCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATCGAGGACCGGCAGCGCTTCCTCCCAACCCTTCGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCAGAACAAT	GCACAAACCGAAGCCGAAGCCAGTTAAGCGACCAGGTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGGGCTAGTGGTGAATGGGCTTCGCGCGATCCGCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAATTCCATGTCGCTGGCCTGCCGAAACCCCAAGGGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAGCTCGCGGAGGAGAACAGGCGGGCCATCAAAGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTTTCGACGGGTCCGCGAGGTGTTGCAGCATCGTCTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTAGGGGGAGTGATGTCCGCACCATGCTGGCGAATCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGCTGTGGCAGTAACCACCCCCCTGGACCTGCTCGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TAACATCCTTCATTTTGAAAAAAGGGGATAAAAATAAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGAGGATGAGGCGTGGCCTCATGTCGAGACCTTGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGGTACGCCAGCGGATGGTACCCATCCACGGGGAACTC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AATTGGGGTCTATCGTAATTGAACAGTCCCAAGGAAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AGCGATGACGGCAGGAAGGAGTGAGCGTGGGCCGCAA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CCGAGAGGACTGCCTTCGCCCCCTGGGAGGGGGTATC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CTGGACGAACCGCACCCCCAGCACCCTCGTTTGAAGAAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ACCTTCGCGGATGCCGCAGCGATCGCGGTACTCGGGTC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCCGCCGCATGACCGCCATCACCCTAACGGGGAATCT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCAACGCGGTGTTCGCAGATTCCTGAACACCGTAACC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CACTACCGAGTTTTCCACATTGGTGACCTCACGGAG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GGCAGCAATCCACCGAGCGGTGTCGCTCTCCGTACCTTGAG
GTCTCAATGAAGCCCGGCCTGGAAGACCGGAACAAT	CAGGAGATTCCCGTTCTACTGCAAGCTCAGCCCCAAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCTGCAGCCGCCCGGACTGCCCGGGGTGCGTGTGGCAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	TATGCGGAACCCGTACAAGGTCCCTAAGTATCTTCAAAA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CACACCGGAAGGTGCGCTGTGAACGGTGTCGACGACATC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AAACTCGTCTACCTGTCCGAGAAGTACAATCCACT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CAGTGTTCAAAACTATTGAATTGACCGTCAAGGGTCA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CGGAGGCGCACCGTGATCATGTGCACGCGTACTTCGGTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CAGAGGACGCCATTGAGGGGCTCTGCTACCGCGGTGAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ATGGGTTTCAGGACACTGTTCCACACTGCCGTCAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CATGGAAATTCTGTGCGAGCCGTACTGGCTCAAGAAGT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CCCGACCCCCTCATGGGGACAACCGACTGCCGACACTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ATGCCACCTTCACCGGCCGACATTGTTCGGGGTGTGTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CGGATCCTGCTTGAAACGGCGGCCGTAATTCAACG
GTCTCAATGAAGTCTGGCCTGGAAGACCGGAACAAT	ATAGCATGCGGACTTGTTCATCGGTCAGCTGATTAATTT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCAGCCATCCGCTCTTCCCGGTATCGCCGCAGATAGAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CTGGAACAATACCGCAATGGACATAAACTACTGTTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCGGCTCACCAACCTCTACGCCACCTACGGGCAGCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGCCACCGCGCCCAGCGGCGCGGCGGCGAGCAGGGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTTCGGTCTTCCTCTGAGGCGGCCAGGCTCCGTCGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGATCTGGGCCACAGACTCCCACATTAGTAGCTTTCGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGGGCCGATGAGGACAAGTTCATCCTCGAGCTGTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTGCTTGTGGAGTTCCGCGGACACTTGGTCTATG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGATGCTAATTCGCTTGAACAGCGCGCAGAAAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATGACGGCTTGTTCTTCGAGGTTGCCTGTTTCCCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGACAACGGTGATGCGCTGTGGCGGGTCATCTGGGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGAACAATTCCCACGCGGCCGCCTCAACGACGTTCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAAAGTGTTCCGAGCTATTGCCTTCATGGCGGTAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTGATATCGCGTATCCGCAAATACGACCCCGTCGGATA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGGCAATTATCGGAATGGTCAACGCAATCAAGAAGCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCTGCCCATGCAAAGTATCTGGACTTCATTGAAGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATGATGGCGATACCGAGGATGTAGAGGCTGTGGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCACCCTCGACATCGTGGTTCACGGGGAGGTATTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGACTTCCTCATCGAGTTGCTCCGCGACAACCTCCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGACAAAGTGCGGGAATTGATTCATGAAACAAAGATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TATACTAGTAGACATCAGGGCGGGAGGCCCTGAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTAGTACAGATCCACCAACTGACGGTACACCATCCAC
GTCTCAATGAAGTCCGGCCTGGAAGGCCGGAACAAT	CAGAACACCTGATTGATTCTGAAGGCCCCAAAGGGCT
GTCTAAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGGCTTGCTCAGGCCACCGCCAGGCTCGCCCCTCAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACGGTGGACTCCACACGAATACCCCCGCGCTTGTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTATTACCAAACCCGGACGTATCTTGAAAGCCGCATCAAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGCGCTGACGGTCATTATGGCCATTCGCACATTTCTAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGCCTCGGTGAAATCCGAGAGACTCTCGAGGCCTGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGAGATTCAGAAGCTGACCAACCCTGCGGTCAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAAATGCTCAGGCCATTGCCGAGGTGAAAGAAGCTCA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGAGATTCAGAAGCTGACCAACCCTGCGGTCAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAGGGCAACGAGGCCGCCGCGCTGGAATTGGCATC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGCGCTGCTCGCGTTCGCCGTCCACGACCCCGAGTGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTCGTGTGGAGGCCACTTATGCTCTTCCTGCCGTCATG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAAAGGTCTTGTTACGCTTGCCAAGAAGGGCGAGGATCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGTCTGGTTCCTTATGTGGATGCTTCCGGGAATGTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGCCTGCGAAATGGCGCTACGGGAAGTCGGCGTCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGTTTTTGGGCGGGCCTATCAATATCACAAGACCGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCTGGCCCTGTGGGATTACTCCTGGGGCCGGCTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAGAGTCACAAAATTAAATCGTGCTCGAGTAAAGCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGGCGGCCTGGATGCGGGCTGCGAAGAGGCTGGTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGAGTGGGCCTACCAAGAAGTGTGCGGGAGACCCATGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGCACTTGTCGCCGAGGTGGGTGGGGAAGTTGATGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGCGAAGCCGTCGGACTGGATCCTAAGCAGGCTATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGTTCGTAAAGAATTCGACCTCCGCCTCGATGAAATC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAACCCGCTACCTGACGCGCGGGGAGGGCGACTCCCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGCGATTATCGGTCAAGATCAAGAATTGACCTACAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTCCTGTCGAAGCAGAGCCCCGCCCTGGCGAAAAAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGACTGGCAGGGCCACGTAATCGCGGCGTACTGCGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCACTGAAAGTGAGGTAAAACATGAGTAAACGACAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGCCGTCTACTGGCAGTGCCGCGCGTGCCTCGAACTCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCGCGGCAGTGCTGCGGGGCTCCACGCGGGAAGAACTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAAGTCGCAGGTCATGGTGGGGATGGTGTTGATGCCGGCGTGGGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACACCGGCGTCATCTCGGTAAACATACGAGACGACC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATTGACTTCGCACGCTGTGACGGTTGGATCAACACG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGCAGGAAGTAATTCCAATACAGGCCCTTCGGATTCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCCGTCGAAGGATCGGACGGATCCGCGACGAGGTTAGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTCACCTCGCCCGCCACGGCATCACCCCCACCAGTCCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCCACTTCGAGGTTCGGTCGAAATCGATCGCGAAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATTACGAGGATCTTGGCGGCAAGGAGCGCGCCCCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTCAAGAAAGGTATCGGAGAAGTAAACGAGATAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCCCGCCGACATTGCACGCGGGGTCTGGCGGTACTGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGCATACCGCACAGCCCGGAGCGACGGGCAGAGTTTCGAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GACCTTCCTCATAAAGCGTATGACTATTCCTTAAGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAAGGGTTCGAACATTGATCTGCACTCGACGGAGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GAACGCGGGGCCTTTCGTGAACTTCGGGCCAGAGTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATACGTCGTCTACCGTGATGTGAAGATTGGGGATCCTGAGAC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTTGCATCCATGACTGCTACCACGGGGGTGCCTTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATCAACCCGTCAAACCGACGCCGTCCTCACCGAACTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATCCCATGACTCATGCAAAATATGGAGGTATCTACTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGGTAACGCCATGGCCTCAGTTGGGACACTGTGGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCCCATGAGTAAACTTGACGAGCGCATAGTCTCGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCACGTCGAAGTTGAAGCCCACTGGCGAGACAGCAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGTAAGGTATGAGTGGGTTCAATTCGATGATTTCAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAACGGGAGGTGGATTTCGATTGAGCGCCAAGATCAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCATGTTCACAAGGACGGTGTGTTGCTGGAAGCTCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGACGGAGCAGCAGAAAGCAACGGTGGAGATCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GAGGCTGACCATCTGGTTTGGTATTCATTGGTATATCAGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAGCAACAACCGAACCACCCAGCCATCGACCCTGCTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGTGTATTCCTGGCTGGGGAAGAAAACAAACATAGAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAAGCCATTCTTGGAGTTCATCCAACTCGGCTTCTGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCGCAGCCGCGTCGCCGTCGACTCCTCCGCGGAGGGCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCAGCCGAAAGCTCAACGGCCACACCTCCTTCCTGGTC
GTCTCAATGAGGTCCGGCCTAGAAGGCCGGAACAAT	CCGCAGTCAGGGATGTAGGTGCGCCACACCTTGAAGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCTCGCCGATATCCCGAACATTTGTGTCGCCTATAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCGCGAAGCGGCGCTGGACGAGCTCAACGTCCACTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCTTGCGACAGTGGCGAGACCGCCGGCGACGAGGAAAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAATCAAGATCCAGGCCTCCGCCACCTTGGTGGAAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCATCCCCGGATTCAGGCCCGATGAACCCGACCAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GACGCGGGCGGCGACAACGTCCACGAGTACAAGTCCCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATCCCCCCACATCCGCGAGATCCAGCCCGAACCCGAACCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGATTACGTCATGGAGCAGACCGATATCCTGTAAGGGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGTGCTGTCCAAAGGTGCTCTGACTGAGGACCAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGACGTCATCACGTTCTTCCGGAACCTACCCGGCCA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACTTGGATAAGAATCTCAATGGAATCCCGGATTCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGAGGAGGCCTGGGCGGTCCTGGCCCGCATATCCGGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGGTCTGCGTACGCAAGCCCGGCCGATCCACCAACC


>LR134535|9|5|2906498-2909769|PILER-CR
	AACACCTACGCTGACAAGACCATCTACAACTTCACCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATCGAGGACCGGCAGCGCTTCCTCCCAACCCTTCGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCAGAACAAT	GCACAAACCGAAGCCGAAGCCAGTTAAGCGACCAGGTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGGGCTAGTGGTGAATGGGCTTCGCGCGATCCGCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAATTCCATGTCGCTGGCCTGCCGAAACCCCAAGGGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAGCTCGCGGAGGAGAACAGGCGGGCCATCAAAGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTTTCGACGGGTCCGCGAGGTGTTGCAGCATCGTCTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTAGGGGGAGTGATGTCCGCACCATGCTGGCGAATCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGCTGTGGCAGTAACCACCCCCCTGGACCTGCTCGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TAACATCCTTCATTTTGAAAAAAGGGGATAAAAATAAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGAGGATGAGGCGTGGCCTCATGTCGAGACCTTGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGGTACGCCAGCGGATGGTACCCATCCACGGGGAACTC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AATTGGGGTCTATCGTAATTGAACAGTCCCAAGGAAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AGCGATGACGGCAGGAAGGAGTGAGCGTGGGCCGCAA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CCGAGAGGACTGCCTTCGCCCCCTGGGAGGGGGTATC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CTGGACGAACCGCACCCCCAGCACCCTCGTTTGAAGAAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ACCTTCGCGGATGCCGCAGCGATCGCGGTACTCGGGTC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCCGCCGCATGACCGCCATCACCCTAACGGGGAATCT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCAACGCGGTGTTCGCAGATTCCTGAACACCGTAACC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CACTACCGAGTTTTCCACATTGGTGACCTCACGGAG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GGCAGCAATCCACCGAGCGGTGTCGCTCTCCGTACCTTGAG
GTCTCAATGAAGCCCGGCCTGGAAGACCGGAACAAT	CAGGAGATTCCCGTTCTACTGCAAGCTCAGCCCCAAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCTGCAGCCGCCCGGACTGCCCGGGGTGCGTGTGGCAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	TATGCGGAACCCGTACAAGGTCCCTAAGTATCTTCAAAA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CACACCGGAAGGTGCGCTGTGAACGGTGTCGACGACATC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	AAACTCGTCTACCTGTCCGAGAAGTACAATCCACT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CAGTGTTCAAAACTATTGAATTGACCGTCAAGGGTCA
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CGGAGGCGCACCGTGATCATGTGCACGCGTACTTCGGTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CAGAGGACGCCATTGAGGGGCTCTGCTACCGCGGTGAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ATGGGTTTCAGGACACTGTTCCACACTGCCGTCAC
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CATGGAAATTCTGTGCGAGCCGTACTGGCTCAAGAAGT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CCCGACCCCCTCATGGGGACAACCGACTGCCGACACTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	ATGCCACCTTCACCGGCCGACATTGTTCGGGGTGTGTG
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CGGATCCTGCTTGAAACGGCGGCCGTAATTCAACG
GTCTCAATGAAGTCTGGCCTGGAAGACCGGAACAAT	ATAGCATGCGGACTTGTTCATCGGTCAGCTGATTAATTT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	GCAGCCATCCGCTCTTCCCGGTATCGCCGCAGATAGAT
GTCTCAATGAAGTCCGGCCTGGAAGACCGGAACAAT	CTGGAACAATACCGCAATGGACATAAACTACTGTTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCGGCTCACCAACCTCTACGCCACCTACGGGCAGCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGCCACCGCGCCCAGCGGCGCGGCGGCGAGCAGGGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTTCGGTCTTCCTCTGAGGCGGCCAGGCTCCGTCGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGATCTGGGCCACAGACTCCCACATTAGTAGCTTTCGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGGGCCGATGAGGACAAGTTCATCCTCGAGCTGTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTGCTTGTGGAGTTCCGCGGACACTTGGTCTATG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGATGCTAATTCGCTTGAACAGCGCGCAGAAAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATGACGGCTTGTTCTTCGAGGTTGCCTGTTTCCCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGACAACGGTGATGCGCTGTGGCGGGTCATCTGGGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGAACAATTCCCACGCGGCCGCCTCAACGACGTTCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAAAGTGTTCCGAGCTATTGCCTTCATGGCGGTAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTGATATCGCGTATCCGCAAATACGACCCCGTCGGATA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGGCAATTATCGGAATGGTCAACGCAATCAAGAAGCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCTGCCCATGCAAAGTATCTGGACTTCATTGAAGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATGATGGCGATACCGAGGATGTAGAGGCTGTGGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCACCCTCGACATCGTGGTTCACGGGGAGGTATTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGACTTCCTCATCGAGTTGCTCCGCGACAACCTCCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGACAAAGTGCGGGAATTGATTCATGAAACAAAGATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TATACTAGTAGACATCAGGGCGGGAGGCCCTGAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTAGTACAGATCCACCAACTGACGGTACACCATCCAC
GTCTCAATGAAGTCCGGCCTGGAAGGCCGGAACAAT	CAGAACACCTGATTGATTCTGAAGGCCCCAAAGGGCT
GTCTAAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGGCTTGCTCAGGCCACCGCCAGGCTCGCCCCTCAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACGGTGGACTCCACACGAATACCCCCGCGCTTGTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTATTACCAAACCCGGACGTATCTTGAAAGCCGCATCAAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGCGCTGACGGTCATTATGGCCATTCGCACATTTCTAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGCCTCGGTGAAATCCGAGAGACTCTCGAGGCCTGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGAGATTCAGAAGCTGACCAACCCTGCGGTCAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAAATGCTCAGGCCATTGCCGAGGTGAAAGAAGCTCA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGAGATTCAGAAGCTGACCAACCCTGCGGTCAGGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAGGGCAACGAGGCCGCCGCGCTGGAATTGGCATC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGCGCTGCTCGCGTTCGCCGTCCACGACCCCGAGTGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTCGTGTGGAGGCCACTTATGCTCTTCCTGCCGTCATG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAAAGGTCTTGTTACGCTTGCCAAGAAGGGCGAGGATCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGTCTGGTTCCTTATGTGGATGCTTCCGGGAATGTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGCCTGCGAAATGGCGCTACGGGAAGTCGGCGTCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGTTTTTGGGCGGGCCTATCAATATCACAAGACCGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCTGGCCCTGTGGGATTACTCCTGGGGCCGGCTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAGAGTCACAAAATTAAATCGTGCTCGAGTAAAGCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCGGCGGCCTGGATGCGGGCTGCGAAGAGGCTGGTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGAGTGGGCCTACCAAGAAGTGTGCGGGAGACCCATGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGCACTTGTCGCCGAGGTGGGTGGGGAAGTTGATGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAGCGAAGCCGTCGGACTGGATCCTAAGCAGGCTATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGGTTCGTAAAGAATTCGACCTCCGCCTCGATGAAATC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AAACCCGCTACCTGACGCGCGGGGAGGGCGACTCCCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGCGATTATCGGTCAAGATCAAGAATTGACCTACAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTCCTGTCGAAGCAGAGCCCCGCCCTGGCGAAAAAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGACTGGCAGGGCCACGTAATCGCGGCGTACTGCGAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCACTGAAAGTGAGGTAAAACATGAGTAAACGACAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGCCGTCTACTGGCAGTGCCGCGCGTGCCTCGAACTCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATCCGCGGCAGTGCTGCGGGGCTCCACGCGGGAAGAACTGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAATAAGTCGCAGGTCATGGTGGGGATGGTGTTGATGCCGGCGTGGGGTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACACCGGCGTCATCTCGGTAAACATACGAGACGACC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATTGACTTCGCACGCTGTGACGGTTGGATCAACACG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGCAGGAAGTAATTCCAATACAGGCCCTTCGGATTCT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCCGTCGAAGGATCGGACGGATCCGCGACGAGGTTAGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GTCACCTCGCCCGCCACGGCATCACCCCCACCAGTCCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCCACTTCGAGGTTCGGTCGAAATCGATCGCGAAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GATTACGAGGATCTTGGCGGCAAGGAGCGCGCCCCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTCAAGAAAGGTATCGGAGAAGTAAACGAGATAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TCCCGCCGACATTGCACGCGGGGTCTGGCGGTACTGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCGCATACCGCACAGCCCGGAGCGACGGGCAGAGTTTCGAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GACCTTCCTCATAAAGCGTATGACTATTCCTTAAGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAAGGGTTCGAACATTGATCTGCACTCGACGGAGCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GAACGCGGGGCCTTTCGTGAACTTCGGGCCAGAGTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATACGTCGTCTACCGTGATGTGAAGATTGGGGATCCTGAGAC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGTTGCATCCATGACTGCTACCACGGGGGTGCCTTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CATCAACCCGTCAAACCGACGCCGTCCTCACCGAACTA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATCCCATGACTCATGCAAAATATGGAGGTATCTACTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TGGTAACGCCATGGCCTCAGTTGGGACACTGTGGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCCCATGAGTAAACTTGACGAGCGCATAGTCTCGAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCACGTCGAAGTTGAAGCCCACTGGCGAGACAGCAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATGTAAGGTATGAGTGGGTTCAATTCGATGATTTCAT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGAACGGGAGGTGGATTTCGATTGAGCGCCAAGATCAA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCATGTTCACAAGGACGGTGTGTTGCTGGAAGCTCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ACGACGGAGCAGCAGAAAGCAACGGTGGAGATCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GAGGCTGACCATCTGGTTTGGTATTCATTGGTATATCAGT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCAGCAACAACCGAACCACCCAGCCATCGACCCTGCTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGTGTATTCCTGGCTGGGGAAGAAAACAAACATAGAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAAGCCATTCTTGGAGTTCATCCAACTCGGCTTCTGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCGCAGCCGCGTCGCCGTCGACTCCTCCGCGGAGGGCGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CTCAGCCGAAAGCTCAACGGCCACACCTCCTTCCTGGTC
GTCTCAATGAGGTCCGGCCTAGAAGGCCGGAACAAT	CCGCAGTCAGGGATGTAGGTGCGCCACACCTTGAAGTC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CCTCGCCGATATCCCGAACATTTGTGTCGCCTATAG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCGCGAAGCGGCGCTGGACGAGCTCAACGTCCACTT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCTTGCGACAGTGGCGAGACCGCCGGCGACGAGGAAAGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CAATCAAGATCCAGGCCTCCGCCACCTTGGTGGAAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GCCATCCCCGGATTCAGGCCCGATGAACCCGACCAGGC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GACGCGGGCGGCGACAACGTCCACGAGTACAAGTCCCTG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	ATCCCCCCACATCCGCGAGATCCAGCCCGAACCCGAACCG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	AGATTACGTCATGGAGCAGACCGATATCCTGTAAGGGG
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	TTGTGCTGTCCAAAGGTGCTCTGACTGAGGACCAATT
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CGACGTCATCACGTTCTTCCGGAACCTACCCGGCCA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	CACTTGGATAAGAATCTCAATGGAATCCCGGATTCC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGAGGAGGCCTGGGCGGTCCTGGCCCGCATATCCGGA
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT	GGGGTCTGCGTACGCAAGCCCGGCCGATCCACCAACC
GTCTCAATGAAGTCCGGCCTAGAAGGCCGGAACAAT

Protein	Signature genes	Signature genes Name	Protein_function
LR134535.1\|VEJ59710.1\|2896241_2896706_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|235668
LR134535.1\|VEJ59724.1\|2913371_2914310_-\|CRISPR-associated-protein-GSU0053/csb1,-Dpsyc-system	cas7	cd09738_cas7_CAS-I-U	gnl\|CDD\|378223
LR134535.1\|VEJ59713.1\|2898231_2898576_+\|HTH-type-transcriptional-regulator-CmtR	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
LR134535.1\|VEJ59729.1\|2921309_2921852_+\|Bacterial-regulatory-proteins,-tetR-family	unknown	unknown	gnl\|CDD\|366102
LR134535.1\|VEJ59714.1\|2898572_2899577_+\|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	unknown	unknown	gnl\|CDD\|224151
LR134535.1\|VEJ59706.1\|2892831_2893599_-\|Bacterial-protein-of-uncharacterised-function-(DUF881)	unknown	unknown	gnl\|CDD\|377575
LR134535.1\|VEJ59721.1\|2909941_2910226_-\|CRISPR-associated-endoribonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
LR134535.1\|VEJ59707.1\|2893688_2893985_+\|putative-septation-inhibitor-protein	unknown	unknown	gnl\|CDD\|377706
LR134535.1\|VEJ59727.1\|2919256_2920636_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ59711.1\|2896768_2897239_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ59723.1\|2911896_2913393_-\|CRISPR-associated-protein-GSU0054/csb2,-Dpsyc-system	csb2gr5	cls000315_csb2gr5_CAS-I-U	gnl\|CDD\|274005
LR134535.1\|VEJ59725.1\|2914306_2916502_-\|CRISPR-associated-protein-Csx17,-subtype-Dpsyc	cas8u1	cd09767_cas8u1_CAS-I-U	gnl\|CDD\|274989
LR134535.1\|VEJ59709.1\|2894707_2896228_+\|Lysylphosphatidylglycerol-biosynthesis-bifunctional-protein-LysX	unknown	unknown	gnl\|CDD\|234778
LR134535.1\|VEJ59708.1\|2893988_2894666_+\|Phosphatase-YfbT	unknown	unknown	gnl\|CDD\|319829
LR134535.1\|VEJ59712.1\|2897359_2898124_-\|Domain-of-uncharacterised-function-(DUF364)	unknown	unknown	gnl\|CDD\|377194
LR134535.1\|VEJ59730.1\|2921848_2923594_+\|Putative-multidrug-export-ATP-binding/permease-protein-SAV1866	unknown	unknown	gnl\|CDD\|224055
LR134535.1\|VEJ59705.1\|2892206_2892671_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ59726.1\|2916498_2919003_-\|helicase-Cas3	cas3	cd09696_cas3_CAS-I-U	gnl\|CDD\|224124
LR134535.1\|VEJ59722.1\|2910229_2911894_-\|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
LR134535.1\|VEJ59728.1\|2920807_2921080_+\|Rieske-[2Fe-2S]-domain	unknown	unknown	gnl\|CDD\|239550

Protein	Function_ID	Function_description	E-value
LR134535.1\|VEJ59710.1\|2896241_2896706_-\|Uncharacterised-protein	gnl\|CDD\|235668	PRK06007, fliF, flagellar basal body M-ring protein FliF.	0.00260974
LR134535.1\|VEJ59724.1\|2913371_2914310_-\|CRISPR-associated-protein-GSU0053/csb1,-Dpsyc-system	gnl\|CDD\|378223	pfam09617, Cas_GSU0053, CRISPR-associated protein GSU0053 (Cas_GSU0053). This entry is found in CRISPR-associated (cas) proteins in the genomes of Geobacter sulfurreducens PCA and Desulfotalea psychrophila LSv54 (both Desulfobacterales from the Deltaproteobacteria), Gemmata obscuriglobus (a Planctomycete), and Actinomyces naeslundii MG1 (Actinobacteria).	2.41629e-41
LR134535.1\|VEJ59713.1\|2898231_2898576_+\|HTH-type-transcriptional-regulator-CmtR	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	5.64529e-15
LR134535.1\|VEJ59729.1\|2921309_2921852_+\|Bacterial-regulatory-proteins,-tetR-family	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.32749e-07
LR134535.1\|VEJ59714.1\|2898572_2899577_+\|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	6.83344e-86
LR134535.1\|VEJ59706.1\|2892831_2893599_-\|Bacterial-protein-of-uncharacterised-function-(DUF881)	gnl\|CDD\|377575	pfam05949, DUF881, Bacterial protein of unknown function (DUF881). This family consists of a series of hypothetical bacterial proteins. One of the family members YlxW from Bacillus subtilis is thought to be involved in cell division and sporulation.	7.64144e-52
LR134535.1\|VEJ59721.1\|2909941_2910226_-\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	3.09011e-19
LR134535.1\|VEJ59707.1\|2893688_2893985_+\|putative-septation-inhibitor-protein	gnl\|CDD\|377706	pfam06781, CrgA, Cell division protein CrgA. CrgA is a trans-membrane (TM) protein, first described in Streptomyces as being required for sporulation through the coordination of several aspects of reproductive growth. In Mtb (Mycobacterium tuberculosis ) CrgA is a central component of the divisome, and consists of 93 residues with two predicted TM helices (TM1: residues 29-51; and TM2: residues 66-88). CrgA facilitates the recruitment of the proteins essential for peptidoglycan synthesis to the divisome and also stabilizes the divisome. Reduced production of CrgA results in elongated cells and reduced growth rate, and loss of CrgA impairs peptidoglycan synthesis. CrgA has homologs in other actinomycetes.	1.52893e-28
LR134535.1\|VEJ59723.1\|2911896_2913393_-\|CRISPR-associated-protein-GSU0054/csb2,-Dpsyc-system	gnl\|CDD\|274005	TIGR02165, CRISPR-associated_protein_GSU0054_family, CRISPR-associated protein GSU0054/csb2, Dpsyc system. This model represents a CRISPR-associated protein from the Dpsyc subtype (a type I-C variant), named for Desulfotalea psychrophila LSv54. CRISPR systems confer resistance in prokaryotes to invasive DNA or RNA, including phage and plasmids. CRISPR-associated proteins typically are found near CRISPR repeats and other CRISPR-associated proteins, have low levels of sequence identify, have sequence relationships that suggest lateral transfer, and show some sequence similarity to DNA-active proteins such as helicases and repair proteins.	3.94158e-28
LR134535.1\|VEJ59725.1\|2914306_2916502_-\|CRISPR-associated-protein-Csx17,-subtype-Dpsyc	gnl\|CDD\|274989	TIGR04113, hypothetical_protein_AaLAA1DRAFT_1703, CRISPR-associated protein Csx17, subtype Dpsyc. Members of this protein family are found exclusively in CRISPR-associated (cas) type I system gene clusters of the Dpsyc subtype. Markers for that type include a variant form of cas3 (model TIGR02621) and the GSU0054-like protein family (model TIGR02165). This family occurs in less than half of known Dpsyc clusters.	6.96935e-114
LR134535.1\|VEJ59709.1\|2894707_2896228_+\|Lysylphosphatidylglycerol-biosynthesis-bifunctional-protein-LysX	gnl\|CDD\|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0
LR134535.1\|VEJ59708.1\|2893988_2894666_+\|Phosphatase-YfbT	gnl\|CDD\|319829	cd07527, HAD_ScGPP-like, subfamily of beta-phosphoglucomutase-like family, similar to Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). This subfamily includes Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). GPP1p and GPP2p are involved in glycerol biosynthesis, GPP1 is induced in response to both anaerobic and hyperosmotic stress, GPP2 is induced in response to hyperosmotic or oxidative stress, and during diauxic shift; overexpression of DOG1 or DOG2 confers 2-deoxyglucose resistance. These belong to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), and Escherichia coli 6-phosphogluconate phosphatase YieH. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	5.65191e-46
LR134535.1\|VEJ59712.1\|2897359_2898124_-\|Domain-of-uncharacterised-function-(DUF364)	gnl\|CDD\|377194	pfam04016, DUF364, Putative heavy-metal chelation. This domain of unknown function has a PLP-dependent transferase-like fold. Its genomic context suggests that it may have a role in anaerobic vitamin B12 biosynthesis. This domain is often found at the C-terminus of proteins containing DUF4213, pfam13938. The structure of UnioProtKB:B8FUJ5, Structure 3l5o, suggests that the protein has an enolase N-terminal-like fold and this Rossmann-like C-terminal domain. Structural and bioinformatic analyses reveal partial similarities to Rossmann-like methyltransferases, with residues from the enolase-like fold combining to form a unique active site that is likely to be involved in the condensation or hydrolysis of molecules implicated in the synthesis of flavins, pterins or other siderophores. The protein may be playing a role in heavy-metal chelation.	1.75351e-35
LR134535.1\|VEJ59730.1\|2921848_2923594_+\|Putative-multidrug-export-ATP-binding/permease-protein-SAV1866	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	4.96294e-162
LR134535.1\|VEJ59728.1\|2920807_2921080_+\|Rieske-[2Fe-2S]-domain	gnl\|CDD\|239550	cd03467, Rieske, Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes. The Rieske domain can be divided into two subdomains, with an incomplete six-stranded, antiparallel beta-barrel at one end, and an iron-sulfur cluster binding subdomain at the other. The Rieske iron-sulfur center contains a [2Fe-2S] cluster, which is involved in electron transfer, and is liganded to two histidine and two cysteine residues present in conserved sequences called Rieske motifs. In RO systems, the N-terminal Rieske domain of the alpha subunit acts as an electron shuttle that accepts electrons from a reductase or ferredoxin component and transfers them to the mononuclear iron in the alpha subunit C-terminal domain to be used for catalysis.	1.39788e-13
LR134535.1\|VEJ59726.1\|2916498_2919003_-\|helicase-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.02552e-35
LR134535.1\|VEJ59722.1\|2910229_2911894_-\|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	6.54588e-105

>LR134535.1|VEJ59714.1|2898572_2899577_+|Cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter
MSEHHNHDTHEHEHHDESHDHDHHGHGHGHGHSHNHAHGSTNRKRLGIALGITGLIFAAEVIGAIVTDSLALLVDAGHMLTDSLGLVVALIAATLMKRPPSERHTWGWQRAEVLSAGAQSAILLCVGGYAIYEGVLRLFAPPDVEAGGVAVIGVVGLLGNVASLLVLLGGKDSNLNMRAAFLEVLNDALGSVAVIVSAVVIALTGWTRADTIAGLLVAALIVPRALKLLRESGSILLEATPTELDLTKVRQHLLERPHVKEVHDLHASVVSTELPILTAHVVLADECFTDGHSQEILADIQECLIKHHEIRIEHCTLQLESEKVAEKHKEHLHA
>LR134535.1|VEJ59713.1|2898231_2898576_+|HTH-type-transcriptional-regulator-CmtR
MTMKETETSDTEMAATLFRSLADPNRLAIVKHLMLSEHRVADLVGHLGLAQSTVSAHVRGLRDSGLLTARVRGRATFYSLAEPELTTNLLAAADDLLVATGEVPVICEPEVEAP
>LR134535.1|VEJ59712.1|2897359_2898124_-|Domain-of-uncharacterised-function-(DUF364)
MPNPWEIYDALTDAIPEEVTLTTVNVGAQWTRVINSAGGIGMAWTMNVKTRPDIFPGVTLDGIPLREAAGLIRSWNLAESSIGQAAINSWHSRPETAEANGFVPTGQGINWGMVFDPYATDVAGKKVAVVGHFPFAQKALEAAGEYICLERNPQPGDYPDSACEYLLPECDYVFISGSSFVNKTAPRLIELSRNAHTVLVGPSVPLNPLLFDHGVDTITGFVSPNPQQLDRALAGVNMKGMFAAGYRVHQHRPA
>LR134535.1|VEJ59711.1|2896768_2897239_-|Uncharacterised-protein
MIVYKGWGVLGILLPLLGVGLMCGIASLFNPSNAVYLKFALIGVVLGSVGTWFVGQWLNQKRPRVKLARWMEERRKELCSLVDQGQFQLAPGVPLPASAEEGYAQVEQKVQQEASEVLPKMTNQHSLYWVPLHWEGIWTGSAALIYFVASFFMSWP
>LR134535.1|VEJ59710.1|2896241_2896706_-|Uncharacterised-protein
MIIFRGWGLLGAAFPALTAFALGVLPASMYGSKSAITNIVAALGALVGGALGFLCGRWLNVIRPRAKVAEWQEQRRAELRARVDAGQFQMAPGLQAPSSREEGYAQVEQLITNESPDVLRQLKNIHTLFFIPMQWFAIGVGVVIFFGALSTALR
>LR134535.1|VEJ59709.1|2894707_2896228_+|Lysylphosphatidylglycerol-biosynthesis-bifunctional-protein-LysX
MTEARTQATEPIDSEQTTVRKEKRARLLAAGSDPYPADLVRSHTLLQVREGWGHLEAGEETDDVVQVGGRVVFIRNTGKLAFATLQDGFTPGDNGERLQVMLSLAEVGTEALAAWKSDVDLGDHVWVEGRVISSKRGELSVMAKRWRMASKALRPLPVLHKELSEESRVRRRYVDLIAREKARAMVRNRAAITHAIRDTLYRQGYIEVETPQLQLVHGGAAARPFTTHLNAFDIDMSLRIALELHLKRTMVGGADRVYEMGRVFRNEGIDSSHSAEFTMLEAYQSWGDQRTIAQLIQDIIVAAADAVGSRQVETGQETIDLDGQWRWLSFFDGLSEAVGREITVETSLEELRAVADEHEVEYDPKWNAGKLSLELFGDLVEPGLIQPTFVHDYPSLAQPLARPHRSEPGKIEAWDLIIDGMERGTGFTELIDPVIQREVLVRQSLAAAAGDPEAMQLDEDFLEALEYGAPPMGGMGLGIDRLVMLLNPGAGIRETILYPLLRPSAG
>LR134535.1|VEJ59708.1|2893988_2894666_+|Phosphatase-YfbT
MGWERTGGEAVGLFDAVILDHDGTIVDSREAMVRAYTRWAGEYGVNLNEMPKYMGMPSRALAEALVPDAKHWDEAAERIEELEVSDTAGVIPMPGAVDAFRVLPGDAVAVATSCTQPLLDARLNAAGLPHPRVVVTRDQVERGKPAPDSFLLAAKRLGVEPSRALVAEDALAGIAAARAGGFPTLGILSTHTADALRADVHVTDLSQVTWDVSDEGIRVIVHDAR
>LR134535.1|VEJ59707.1|2893688_2893985_+|putative-septation-inhibitor-protein
MPESKVRKEAKSKARKKQSEELEKARKERRDRKRLAANTERRWVPWVFIPVGLLGVLWMVTWNLAGNYIGFMRALTEWNILIALGLIIACFSLMTLWK
>LR134535.1|VEJ59706.1|2892831_2893599_-|Bacterial-protein-of-uncharacterised-function-(DUF881)
MSETRLTRLLRRIRGPRSDENPRSLRGRVGTGIICVLAGTMLTASALAARGTDLRSDRNTDLRGLVATQAQRNEQLRKEVAEVRSEVEDLGHKQGASPELERQQRAVAEQAAAVPVTGPGMRVTLTDAPTDVKPAGVDDDALVVHQQDIQAVVNALWKGGAEAVSIQGQRIITTSGIKCVGNSVVLHGIPYAPPYVIEAIGDAGRMAAALKESRALTIYRQYADAYGLGYKETKESSLSLPAFQGALGITHAKPK
>LR134535.1|VEJ59705.1|2892206_2892671_-|Uncharacterised-protein
MVDREVHGGFVSWSRRGVLLVGVGLLAGCGAVDDLVEDRSQLPVLLEDPMAAENLLGLTLKEGSESGYRRPLGKPKFTEVRRVFSLGDDARQEVFDRAVAFAKEAGWKKDFESGLPPNMVWNGQKNNPRRECGVFISDNDAADLMIRLRVFEEP
>LR134535.1|VEJ59721.1|2909941_2910226_-|CRISPR-associated-endoribonuclease-Cas2
MARRRYLISYDISDPKRLRATFNLMKGYGKWLQYSVFVCDLSKAELAMWERDIRDVIALAYDSVVVIDLGAPQDADIRMLGVPRRLPDEGPVVV
>LR134535.1|VEJ59722.1|2910229_2911894_-|CRISPR-associated-endonuclease-Cas1,-subtype-CYANO
MPAQGEYSAEPQLVPARMLNELVYCQRLFHLEWVDGRWAHNDDTIQGSVAHDATDRRSGRMPAPDEEEKPFTSIQVALSDPDLGVTAVIDRVDHEDGSSSPVDMKKGSGPRDGGMWPADRVQVLTQAVLLRRAGYSVNRADISYLGSHHRASIEVGQDAETEVRELVALARKVAAQELPPPPLLNDPRCLRCSLAPLCMPDETNYLLERSGEQPRRIIVKNPDARPVYVNTQGASVKVSGGRLLVAVKGETVAERRLLDVSQVCVVGNVQITTQALRALWRRGAVVIWLSYGGWLDGWSQGPMNGHVTLRRRQVLASVHGLRFAQQMIRGKIHNQRVLLRRNAKVSLDDSVLDQLKELEAKTESAASLETLLGIEGTAARLYFGQFHKLLSPRLEVAAEFQAHGRARRPPPDPVNAVLGFCYSLLTKDLVAVLTGVGLDPFLGVLHQPRYGRPALALDLAEEFRALVAESVALQCLNNGEINEKSFMRGHLGVALTADGRRSVIQAHERRLEMELKHPLFGYQVSYRRVLDLQARVLAASFTGELDSYTPLMTR
>LR134535.1|VEJ59723.1|2911896_2913393_-|CRISPR-associated-protein-GSU0054/csb2,-Dpsyc-system
MDRWGEVTVPTQVALRFVTGKYHANGWDHALNEGVSEWPPSPWRLLRALISVWHTRCDDIPEETISDLLTELATEPPEYLLPDARPSQTRHYMPNPDFLEGVKHSTSLQLDPRLNLDDEAEVLIRWPNLTLPAGQRDALERLLRKLPYLGRAESRCEARLLSEEHSQQEKGWVRPSETGNTQVLVPEPGVTRKQLETSSLEMRKARLRYPSGSRWIRYELPGEALNAPARREVNDLLRPTTVRWRLEPTAPFRVEDGILAAHGLRGRILGTKKENTDLREQGSGVEALAGHHGVFDDGPQHRHPHWLWLPTLGAGGELTGQVEDLVLWVPDGIPADTLSRLAGARYLPRWSNAPKGYRSGAELHLQLMGPVDAVMHEYTSADATTWVSVTPFLTDRFPKLNKPREEFAQKLVERELGFRHPGGTPPVRVKLLADWENRDVVRFRRYRWNESMAQRRRGMLLRLDFDEPLPKGLGERPEPLVLGSLSHFGFGLFRPVER
>LR134535.1|VEJ59724.1|2913371_2914310_-|CRISPR-associated-protein-GSU0053/csb1,-Dpsyc-system
MTSTVLNLTLRPAVGFRFQPTGFPDLGAATYQAHVSGEGWVQALHLESPQSMANRLELCTWDPAANDQAEALRGLPYVRVVDAGGGFLTSSRLEAHRLASAYLMDAKIDGETGRVWLEDRLGLVKGRLVDHRALAKAIFDLDPVSLIHGVFFAQKQWPSQPKVARAITCFIDALDVRPAVSGGVKTDSVNPSNEEGRGAKEGYGMVPHQRVEYTARDITASVVVDHGQIQSYGLGEKSEAVLNALVDFELASLFRQDGLRLRTACHLVVDQDCEDLAKIPALDEATAKLRQAIDQHGDLAPISELKWTGGGK
>LR134535.1|VEJ59725.1|2914306_2916502_-|CRISPR-associated-protein-Csx17,-subtype-Dpsyc
MTTHVFPGLGCVPLINYLAALGVAKGISEQADPAARFGWRNGVFHMDTEVEDVAEFFVRDFVPTPVFSPWNAGSGFGKKDKTPLEYIRILESSTAHRLAPYRNALAVIRSLLIAKSEKGWTKERFVQELRNRLPDDALPWTDASVVLTAKKTEYPPILGTGGNDGRLDFSTNVHQRLKDVLPELGAKPERSRAWMQDLLWGRSTEKLLAASVGQGDPVGAGTPGSSAFGSADAMVNPWGFILMVEGTMLFAASVAKRLGEQNSRVAIPFTVSSSPDGPIPGSANEEGRGELWAPLLESVTLTELRQVFEEARVSWDGGTASSAVSMYAAVRSFGVNRGISAFQRFGFLKRNGLAFVAVPLDHVKVKARPEVVMAKKPLRRARTFHKASGVASKTAARRFDASVTAFVRDPEWWNGIAMLRAQTELELTALRSRKNREELGHPSKLVPANAVIPVCRELFLNSPEARIAAGIASATFLPPTTSQQGGGSGGQPIRRLLVGADPKNPKDPIDPEVMVPGLGARPTVDVLADLVVWLAQHPGEGTRLARGWLPFLSHRYPVSWTDIHAWVGGLLDDDLVTHHLLAFLAVDWSDGNYMDNVTPDGECLFLDPTLAILQALASGSVRVRETAPDATGVVVGLEPSWSLQLRADRVADVHHAASGVINRGTISLSRTGETDIQVHTHSARISRPGLGPRILAALAAPSSQRALKRSAPEIENTDPYENTDLYEGALQ
>LR134535.1|VEJ59726.1|2916498_2919003_-|helicase-Cas3
MMRFSNFTECFRRATRSEGAPDGCDPYRYQVRLADEGFPDALRAPTGSGKTAVVLAYVWRLLFHPDASVRAATPRRLVVLLPSRTLVEQYEETVRGWLDRLGLLDAVGVHVFMGGRDIRSSQQDWRMNLHRPSIVIGTVDMGVSRGLARGYGTFRASYPIDFALIGNGTLMVVDEVQLAPQATATLRQFAAFQRELGTAEPSRLMIMSATIDERVLDTVDNPWGGAGVLEIDESSESPELLRRMSAERTIREFPLVEKPKEFAAQIVERHQPGTLTLVVVDTVDAAVDAYREVGKLAPEEPRLLIHSQFRGVERKAQLEKLRGIARDGGIVVATQAIEAGVDIDARTLITEAAPWASVVQRAGRCNRAARYPVGEAVVHWREPAKGHPYDSEQVACAVEALRRADGMSLTSAQLHRLGDDIPPEDLELRILRRCDFRQLFDTTPDLTGNDIDISCYIRPDKDLDVQLAWIPNGSIAQGKLATEIPGQPLRCGVSMSRAKKLLNRKDIRERRDQRAWTFSIQDDRWIPVRADQLRPQQLILVEAGLGGYSIEHGFDPAEKQTVQDHVAAHDLRDVTTPESVTSSQDAGARGNGWVTLHQHLADTREQVEALAAVLRPAGIDDAHLHAAAVAGVLHDLGKAHHDWARALLEASEDTPPDDPEQLYAKSPGTAPLRVRRELKVGELKNARVERRSGFRHELISVFMLRTDAGRQLLIDLGVEPELHPLVLYLIAAHHGHIRITARDPRYDGVDGLSFLGCVDKEPINAVTLPGIELPESVVDHGIFRSGPDSWTTNALALLERLGPFRLAYLETLVRMADWRASATLELPAAEGIEE
>LR134535.1|VEJ59727.1|2919256_2920636_+|Uncharacterised-protein
MSKPHIKFDHSKPLLSETLSFTILLSMLWILFSFKEFPCKPNDPLHPLDCLNLSWADFNTTIAIIGPAVTAQLALTIASFAPDETCNTAVREHLSRMRDTAGYIAFGLWGLQASLALICLLDATSNPERSSGPPLVTIFLLTLTLFLTVVIADTRGQKEWEMEFERLRRQFRYRRRDLARTHKLRPQGERWAAASALREFLSLFGLTCLVPFGLTTVWLKLAYSPPLSMSEILIIAALATSGTSILLIFCTALSQLSIILIIALPRLTVLRWTPGTAVTLLWAFSSGANLLIDDRLIIKIIFGQWTASSMILGLLLTVALSCRKGPFRWAWHQRYASLDKECKSLKEEIIRMKGMLHSDQYRKMRPREEATGTEIPETSDEKSRDAKPNTESKIALYTVISFLILFTLKKLTKLDGHGLKTTNLKKHLLGIQRENKSSQHPKKAGKHFLKAIHKLHTDR
>LR134535.1|VEJ59728.1|2920807_2921080_+|Rieske-[2Fe-2S]-domain
MPVGGGTLIGWYVVTQPVAGTFHAYYAACPHAGLKVDRIEGQKIVCNSHGARFSTDNGAVLKGSAKKSLTPAPFTTDGDILIITMPKDTE
>LR134535.1|VEJ59729.1|2921309_2921852_+|Bacterial-regulatory-proteins,-tetR-family
MIAATRQLILDHGPEVTTRQVAEAAKVAEGTLFRVFPTRRDLIAATIADHLSPERLADIFAAAPATTTVDETTEVCLSTAADYVTTFGRFIPRPHRGDHQDEIRFRIMELWEARVCDIAGWMRDRLAPHEAELTIPVKDFTHLVITLAMGYAHGRSPDTSLNPAALARLALDGARSKDSL
>LR134535.1|VEJ59730.1|2921848_2923594_+|Putative-multidrug-export-ATP-binding/permease-protein-SAV1866
MIKRLNRLIFTHLKPYWRELLAILALQVLATAMSLYLPNLNAQIIDDGVVKGDTDLIWRSGALMLLFSLVQAAGQISATWFGALTAMSLGRDLRAAIFDRALSFSTREMRDFGASSLLTRNTNDVLQVQTIVQTTLTIIVGAPIMMVGGFVMAVREDFGLSWIIAVSVAVLGVAVSLLVIFVSPLFQRMQTNLDNLNRVLREQISGIRVIRAFIREHHESRRFEGANEDVYSVTLRASRWMVLLFPIAMFMVNISSVAVIWFGAFRIDSGDIQIGQMTAFLNYLIQILISVMMSTMLLFLAPRSAVSADRILEVLDTEPTVAPPADPVAPQELTGVVEFRDVTFTYPGAEDPVLANLSFTLTPGRTTAIIGSTGSGKSTLVNLIPRLYDVSGGEVLVDGVDVRRLDPDALWSRIGLVPQRPYLFSGTVASNLLYGRPDATPEQMWEALRIAQAADFVEKLDGGLAAHIAQGGTNVSGGQRQRLSIARALVKEPAVYVFDDSFSALDVATDARLRAALAPATADRATLIVAQRVATIRGADEILVLEHGRIVGRGTHDELLASNATYQEIVDSQLSAEEAQS

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Crispr_ID: LR134535_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134535_10

2991216-2992107

Orphan

Consensus_repeat	Method
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	PILER-CR
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CRISPRCasFinder
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CRT

12 spacers

The CRISPR arrays of LR134535_10

>merge|LR134535|10|2991216-2992107|PILER-CR,CRISPRCasFinder,CRT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAACAGAGACAACATATCCCACTTAAGATACTCAGACGTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAACAACGTCTTGCTGGTCTCTATGACCTTCTCGCCATATTGTCTCGTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAACGAAGCTGGATAGATCCATTCGATACGGTCAATGTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAACCACGGCAGTGCCGAGGACGATAAAAGGAAGCGGTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAACCGGAACAGCTTCGGCACGAAGCTGAAGGCTTGTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAACAGAGCCCGCCCAGTAAAATCCGCTGTGTAGATGTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAACATAATCCATTTCTCGGGAAATGCTTCGCCGTACCTTGTCTGGAAGCACCGCAAACCTTAAAGCGGATTGAAACCCAGACTAAAGGCATCCGCCACCTTGGACTTTGCCTGTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAACTTCAGATAACGTTTTTTAACGTTACCTGTGAAGTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAACCGTTGGAGATGAAAGATTAACGCTCCATGCCACTAGTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAACGGGATCCGAGCGAGGACTCGTTGATTCAGTTGTAGTCTGGAAGCACCGCGAACCTTAAAACGGATTGAAACAATATCCAGTTAGAATAGGGGGTATAAGGTGCTTGGGTCTGGAAGCACCGTGAGACTTGTTCACAGGCGGCGT

>LR134535|10|6|2991216-2992034|PILER-CR
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	AGAGACAACATATCCCACTTAAGATACTCAGAC
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	AACGTCTTGCTGGTCTCTATGACCTTCTCGCCATATTGTCTC
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	GAAGCTGGATAGATCCATTCGATACGGTCAAT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CACGGCAGTGCCGAGGACGATAAAAGGAAGCG
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CGGAACAGCTTCGGCACGAAGCTGAAGGCTT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	AGAGCCCGCCCAGTAAAATCCGCTGTGTAGAT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	ATAATCCATTTCTCGGGAAATGCTTCGCCGTACCTT
GTCTGGAAGCACCGCAAACCTTAAAGCGGATTGAAAC	CCAGACTAAAGGCATCCGCCACCTTGGACTTTGCCT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	TTCAGATAACGTTTTTTAACGTTACCTGTGAA
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CGTTGGAGATGAAAGATTAACGCTCCATGCCACTA
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	GGGATCCGAGCGAGGACTCGTTGATTCAGTTGTA
GTCTGGAAGCACCGCGAACCTTAAAACGGATTGAAAC

>LR134535|10|10|2991216-2992034|CRISPRCasFinder
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	AGAGACAACATATCCCACTTAAGATACTCAGAC
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	AACGTCTTGCTGGTCTCTATGACCTTCTCGCCATATTGTCTC
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	GAAGCTGGATAGATCCATTCGATACGGTCAAT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CACGGCAGTGCCGAGGACGATAAAAGGAAGCG
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CGGAACAGCTTCGGCACGAAGCTGAAGGCTT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	AGAGCCCGCCCAGTAAAATCCGCTGTGTAGAT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	ATAATCCATTTCTCGGGAAATGCTTCGCCGTACCTT
GTCTGGAAGCACCGCAAACCTTAAAGCGGATTGAAAC	CCAGACTAAAGGCATCCGCCACCTTGGACTTTGCCT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	TTCAGATAACGTTTTTTAACGTTACCTGTGAA
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CGTTGGAGATGAAAGATTAACGCTCCATGCCACTA
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	GGGATCCGAGCGAGGACTCGTTGATTCAGTTGTA
GTCTGGAAGCACCGCGAACCTTAAAACGGATTGAAAC

>LR134535|10|5|2991216-2992107|CRT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	AGAGACAACATATCCCACTTAAGATACTCAGAC
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	AACGTCTTGCTGGTCTCTATGACCTTCTCGCCATATTGTCTC
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	GAAGCTGGATAGATCCATTCGATACGGTCAAT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CACGGCAGTGCCGAGGACGATAAAAGGAAGCG
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CGGAACAGCTTCGGCACGAAGCTGAAGGCTT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	AGAGCCCGCCCAGTAAAATCCGCTGTGTAGAT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	ATAATCCATTTCTCGGGAAATGCTTCGCCGTACCTT
GTCTGGAAGCACCGCAAACCTTAAAGCGGATTGAAAC	CCAGACTAAAGGCATCCGCCACCTTGGACTTTGCCT
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	TTCAGATAACGTTTTTTAACGTTACCTGTGAA
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	CGTTGGAGATGAAAGATTAACGCTCCATGCCACTA
GTCTGGAAGCACCGCGAACCTTAAAGCGGATTGAAAC	GGGATCCGAGCGAGGACTCGTTGATTCAGTTGTA
GTCTGGAAGCACCGCGAACCTTAAAACGGATTGAAAC	AATATCCAGTTAGAATAGGGGGTATAAGGTGCTTGG
GTCTGGAAGCACCGTGAGACTTGTTCACAGGCGGCGT

Protein	Signature genes	Signature genes Name	Protein_function
LR134535.1\|VEJ59791.1\|2997228_2998035_-\|Uncharacterized-proteins,-LmbE-homologs	unknown	unknown	gnl\|CDD\|274915
LR134535.1\|VEJ59781.1\|2983531_2985271_+\|Iron-import-ATP-binding/permease-protein-IrtB	unknown	unknown	gnl\|CDD\|224055
LR134535.1\|VEJ59785.1\|2988249_2990028_-\|Lipid-A-export-ATP-binding/permease-protein-MsbA	unknown	unknown	gnl\|CDD\|224055
LR134535.1\|VEJ59787.1\|2992789_2994625_-\|Lipid-A-export-ATP-binding/permease-protein-MsbA	unknown	unknown	gnl\|CDD\|224055
LR134535.1\|VEJ59782.1\|2985281_2985896_-\|4'-phosphopantetheinyl-transferase-sfp	unknown	unknown	gnl\|CDD\|225002
LR134535.1\|VEJ59788.1\|2994689_2995259_-\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|379470
LR134535.1\|VEJ59795.1\|3001429_3002611_-\|Fructokinase	unknown	unknown	gnl\|CDD\|224851
LR134535.1\|VEJ59778.1\|2979618_2981061_+\|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD	unknown	unknown	gnl\|CDD\|213192
LR134535.1\|VEJ59793.1\|2999039_3000275_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134535.1\|VEJ59792.1\|2998069_2999020_-\|Putative-fructokinase	unknown	unknown	gnl\|CDD\|224851
LR134535.1\|VEJ59779.1\|2981057_2981693_+\|conserved-hypothetical-integral-membrane-protein	unknown	unknown	gnl\|CDD\|370580
LR134535.1\|VEJ59780.1\|2981772_2983539_+\|Iron-import-ATP-binding/permease-protein-IrtA	unknown	unknown	gnl\|CDD\|224055
LR134535.1\|VEJ59789.1\|2995252_2996431_-\|recombination-protein-F	unknown	unknown	gnl\|CDD\|226984
LR134535.1\|VEJ59790.1\|2996631_2997207_+\|Deoxycytidine-triphosphate-deaminase	unknown	unknown	gnl\|CDD\|234753
LR134535.1\|VEJ59783.1\|2986139_2987516_+\|Predicted-ATPase	unknown	unknown	gnl\|CDD\|379114
LR134535.1\|VEJ59794.1\|3000313_3001354_-\|1,5-anhydro-D-fructose-reductase	unknown	unknown	gnl\|CDD\|223745
LR134535.1\|VEJ59786.1\|2992269_2992776_+\|Predicted-acetyltransferase	unknown	unknown	gnl\|CDD\|379112
LR134535.1\|VEJ59776.1\|2977989_2978700_+\|Deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234784
LR134535.1\|VEJ59777.1\|2978965_2979625_+\|Putative-HMP/thiamine-permease-protein-YkoC	unknown	unknown	gnl\|CDD\|223692
LR134535.1\|VEJ59784.1\|2987512_2988133_+\|Uncharacterised-protein	unknown	unknown	gnl\|CDD\|379341

Protein	Function_ID	Function_description	E-value
LR134535.1\|VEJ59791.1\|2997228_2998035_-\|Uncharacterized-proteins,-LmbE-homologs	gnl\|CDD\|274915	TIGR04001, thiol_BshB1, bacillithiol biosynthesis deacetylase BshB1. Members of this protein family are BshB1 (YpjG), an enzyme of bacillithiol biosynthesis; either BshB1 or BshB2 (YojG) must be present, and often both are present. Bacillithiol is a low-molecular-weight thiol, an analog of glutathione and mycothiol, and is found largely in the Firmicutes. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	2.26085e-29
LR134535.1\|VEJ59781.1\|2983531_2985271_+\|Iron-import-ATP-binding/permease-protein-IrtB	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.00548e-117
LR134535.1\|VEJ59785.1\|2988249_2990028_-\|Lipid-A-export-ATP-binding/permease-protein-MsbA	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.03661e-100
LR134535.1\|VEJ59787.1\|2992789_2994625_-\|Lipid-A-export-ATP-binding/permease-protein-MsbA	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.4442e-162
LR134535.1\|VEJ59782.1\|2985281_2985896_-\|4'-phosphopantetheinyl-transferase-sfp	gnl\|CDD\|225002	COG2091, Sfp, Phosphopantetheinyl transferase [Coenzyme metabolism].	1.6068e-31
LR134535.1\|VEJ59788.1\|2994689_2995259_-\|Uncharacterised-protein	gnl\|CDD\|379470	pfam14103, DUF4276, Domain of unknown function (DUF4276). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 224 amino acids in length. There is a single completely conserved residue E that may be functionally important.	1.76454e-20
LR134535.1\|VEJ59795.1\|3001429_3002611_-\|Fructokinase	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.22597e-46
LR134535.1\|VEJ59778.1\|2979618_2981061_+\|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	3.00739e-74
LR134535.1\|VEJ59792.1\|2998069_2999020_-\|Putative-fructokinase	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	5.63011e-47
LR134535.1\|VEJ59779.1\|2981057_2981693_+\|conserved-hypothetical-integral-membrane-protein	gnl\|CDD\|370580	pfam09605, Trep_Strep, Hypothetical bacterial integral membrane protein (Trep_Strep). This family consists of strongly hydrophobic proteins about 190 amino acids in length with a strongly basic motif near the C-terminus. It is found in rather few species, but in paralogous families of 12 members in the oral pathogenic spirochaete Treponema denticola and 2 in Streptococcus pneumoniae R6.	1.65484e-40
LR134535.1\|VEJ59780.1\|2981772_2983539_+\|Iron-import-ATP-binding/permease-protein-IrtA	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.17313e-133
LR134535.1\|VEJ59789.1\|2995252_2996431_-\|recombination-protein-F	gnl\|CDD\|226984	COG4637, COG4637, Predicted ATPase [General function prediction only].	2.03902e-28
LR134535.1\|VEJ59790.1\|2996631_2997207_+\|Deoxycytidine-triphosphate-deaminase	gnl\|CDD\|234753	PRK00416, dcd, deoxycytidine triphosphate deaminase; Reviewed.	5.16491e-94
LR134535.1\|VEJ59783.1\|2986139_2987516_+\|Predicted-ATPase	gnl\|CDD\|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	2.23032e-26
LR134535.1\|VEJ59794.1\|3000313_3001354_-\|1,5-anhydro-D-fructose-reductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.01543e-49
LR134535.1\|VEJ59786.1\|2992269_2992776_+\|Predicted-acetyltransferase	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.36858e-20
LR134535.1\|VEJ59776.1\|2977989_2978700_+\|Deoxyribose-phosphate-aldolase	gnl\|CDD\|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	1.79478e-102
LR134535.1\|VEJ59777.1\|2978965_2979625_+\|Putative-HMP/thiamine-permease-protein-YkoC	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	1.07724e-11
LR134535.1\|VEJ59784.1\|2987512_2988133_+\|Uncharacterised-protein	gnl\|CDD\|379341	pfam13707, RloB, RloB-like protein. This family includes the RloB protein that is found within a bacterial restriction modification operon. This family includes the AbiLii protein that is found as part of a plasmid encoded phage abortive infection mechanism. Deletion within abiLii abolished the phage resistance. The family includes some proteins annotated as CRISPR Csm2 proteins.	3.43038e-28

>LR134535.1|VEJ59785.1|2988249_2990028_-|Lipid-A-export-ATP-binding/permease-protein-MsbA
MLNNWIRVLRLIWSTGRGGVLGILVSTAINALVPAAQVVLLGLTVNAVLNAADAADLLVYPLLFGLVACLDLILTTLQSYWQASLEQKVSNTFNLKLMEKSGELSLPDFENPRVYNMLQLATREATSRPYQLFSQLVATVSGGISLVTVTGIVVSWNPLVALLVLLSPVLPVLVNQLFVKRLWQVERNRSEERRRGQYLLALVTNDKTYKETRLFGLVPHFINTYRQMLGRFYSVDMEIERKRGVAGVLSGLLGVVVTAVAIFFAISDSLAVGDVGRLAAYISAISAVTAAAQMFIGGFGQLFEHTLFLGNLFDFLDLSPTQKQSEDSPRPALRGGDTVEPQEIVFDDVTFQYPGQADAALLNFSATFSPGRTVALVGENGAGKSTIVKLLTRLYEPTSGRILLGGVDIQEIELDVYRDQLAVLFQDFIQYEASLRQNIGFGCLGRLEDGEGILSAARRARLMDVVEDLPHGIDTQLGKWFSEGRQLSGGEWQRVALARALFRGAPIIVLDEPTASLDVQAEEAVFEQMNAEETRATKILISHRFSTVRMADEILVISEGKLIERGTHSSLVTAGGVYAKMYAIQAKGYLDG
>LR134535.1|VEJ59784.1|2987512_2988133_+|Uncharacterised-protein
MSRRKERRPVRSLNRRTGTRRESRRLLVVTEGKAEKEYLEGLMQSLRPDGMQVTPIDVVDGRGEPSKVLKTAKARCHSRADGYDEVWLLLDVDQHAKLTPVLRETRQENFSAAVSNPCFEVWLLWHFEDWTREGSSSEIQHAARRHDLGKSIPPAFPYTKHPEAKRRASRTPVDVNEIGRNPSSALPSPLESILRDSPGGACSQPS
>LR134535.1|VEJ59783.1|2986139_2987516_+|Predicted-ATPase
MHICCMLLLQFSLSNHASFRDEATLNLVSHTLKSQVPRDSHWLRHVSRVAAIYGPNASGKSALLHGMRFFTSMVRNSATTWAGDPKLPLRPFLLDAGSTNRPSTFVLDFVVDDVRYEYGFSLTEHEVTEEWLRGYWTSKPTMLFDRHGGDIEVGRRLRGGAALLSRITGPRELVLSRAFTARHEQLQRLASEIVEGFEFVFHSEQAREERLRQLTTELAGGRFKSDDLVTLLRVADVGICDAEVSERELPEHLKELLMNFDPAANATDSEDPEDDTPPGPARLVLEAGQFEELIIQLRRALRFHHLGIDGAYPLDLNAESAGTLTWLGLAVPALAKLRSGGVLCIDELDASLHPQLAQVLVSMFTDPDINPHGAQLVFTTHDTHFIDNVNPARLTPEQVWFTQKDAQGVSDLFSLDEFPTRAEQNHARRYLSGRYGAVPRIAPAQVRHLVGVQEQLPI
>LR134535.1|VEJ59782.1|2985281_2985896_-|4'-phosphopantetheinyl-transferase-sfp
MVLLADTAAGAAWAPRRGGVLSRDEAERAARFVFPGLGEAWAGAHVLLREVLGRATLIPAADVRIRVGEFGKPSVDGVEFSLSHTGSVVLIGLGDLPLGVDVEKIPEERTVDQVGSSFHPRETAELLGLPAEDRPGAFARVWVRKEALHKAIGTGLSRGISRDYVGTGTVPGTPVAGLRIHDVALPGMPGHRAALCTTVTAAVS
>LR134535.1|VEJ59781.1|2983531_2985271_+|Iron-import-ATP-binding/permease-protein-IrtB
MLERFRKYLDRPQTVYTLILGYTVAAVLQGLAFGALIWFLRGFLSEDPSSATGAFWLLIALGVVSFATMSVTMIAANRISAYDVCGNVIAKIGQRVSGLPLGWFDSGATGRVSAAVTRETDALSHLASIVFPQLISSLVTPATAVVVTLIHDWLLGLVMVVVTPVVWGLWRWAMPLIRREQELTPKVSAETAHRIIEQVRLQPVLRAQGLNGTSWEPLKKALHDEHATVKGLMAAQSRPSAAFGILGQVFFAAVLGTGLALTLGGRLDVPGYLAIGLMAARFTTPISQSVLYAAEIQKSIVSLDAIGAIVDSAPLPEPDEPKVPQGTTIRFNDVHFGYVADQPVFSGLSLTVRENEITALIGPSGCGKSTVTRLAARFWDVDGGSITIGGVDVRDIPTTKLMEMTSMVFQDVYLFNTTITENVRISRPDATDAEVADALHRAGLDQTLSRLPDGAGTQVGEGGQKLSGGERQRVSIARAFLKDAPILLLDEITSALDAENEAAITATLGELSRGRTVIVIAHRLSTVMQADHIHVLSGRENGTPTQVVEEGSPGDLAAGNGVFASLLADFEQTARWRVR
>LR134535.1|VEJ59780.1|2981772_2983539_+|Iron-import-ATP-binding/permease-protein-IrtA
MVATVPRQTPTSVWELIRSAHTAMFLGGVVAFIGAALKIVPYIALVEIGRGFLNGASAAHHWGWFTAAVVSMVIHGIAYTGALGATHIAEANLRNELRLKLVNKLPRVPLGWVNDRSSGQINRAVIGDTEQIHTLVAHLAGDMMNSAGTVVAGFGYLLWLDARFAGLLILAWLLLLGMSTLPATKGMKQSFDEYSAAQRELSSVTVEMVDGIKEVKNFGMTADVFGRFDAAARNHADVTMNWMRRSGVSMAIMAAVMQPAAMLALTIGLGFWFFHLGWVTPITVVAFALVWVGIPEGLTGLVQIFQHIYAAKQAANSTLEILGTPELATPTTRAALTADSSLIEVDDITFGYEPDNPVVKGVTLTCRPGTVTALVGPSGGGKSTLAKLIARFWDVDSGAIRIGGADVREQTDEQLMGSMALVFQDAMIASDTIANNIALGKPEATREQVVEAARKAHVHDRITALPNGYDTMLGTGDGFLSGGEEQRLGIARAFLSAPRILILDEATAQADAHSELEIQRAISGLAEGRTVVMIAHRLSTIRTADQIAVIDEGRITECGSHDELISRDGHYARLWAAQQNTMTGGRDA
>LR134535.1|VEJ59779.1|2981057_2981693_+|conserved-hypothetical-integral-membrane-protein
MMSESTESTQPAAPTPNRRNSPVRDAVTIGIFIALYIVLFFICGMTMGAIPLIMVLLPVIFGIFGGLIFMVLLGKVQRTGIFLITGLIIGLMMISMAPGGVMCYMTIAGGVVAEVIYWLMGHKSFASMTAAYTAFVTFFALGEYIPFVWMKDAYLELYANNPTLDVAKVGMDMLNPATMAMYCLLAIVACVAGCFWGRALTRRQFSRAGIV
>LR134535.1|VEJ59778.1|2979618_2981061_+|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD
MVIEFAEATVSYFGDDETLLPAALSGIDLVIPAGQSVLVTGDSGCGKTTLLRCLNGLVPHFFDAHVTGSITLDGVPVAQLPSRDLASRIGTVFQDPRSEFFTFDVASELAFCCENFAMPSEEIVRRVGEIASEVGITDLLGRRIAGLSGGEKQKLAIGSAMALNPRVLLFDEPSANLDLDGLDMLRGVILDLKERGVTTIIADHRLSYLDGVIDRCIVLETGRVTADITSDRLGQLPDAWFADHGLRRLHRTEFRSAPPDPFDQAGPRIRDIQFAHPRCAPLWRIDELTLPASGVIGITGANGVGKTTLMKVLLGLLKSRGRIGWGERTWTRRQRIRDCALVMQDVEYQLVGESVWDEMLIGSPPGPATEARAVELLARTGLEELRERHPLTLSGGQKQRLGIALACMKQARVICLDEPTSGLDAGNMQRISGLLRDVAGDGALVLVITHDAEFIESTFDHTVHIDDHQVVLEKLARKEE
>LR134535.1|VEJ59777.1|2978965_2979625_+|Putative-HMP/thiamine-permease-protein-YkoC
MLVAMAFGTGLVQVPAGTALLTAYPVALGFLLGSSRLSLQLAGSYVALRVLHHLCLLGAHLPLVPWLGILLTLSVYGFPALAMGLVVFTRVPMGEAMAALGRLRLPGTFLVVVMVIYRYVPTLLGELRTIRSASRLRGSEARWRRWLRHPLKELEHGVVPVLMRSGRIADELSAVAECKGLDPGHRRSAMTVPRLEAVDWVLMALTPALVAAVRVWVRW
>LR134535.1|VEJ59776.1|2977989_2978700_+|Deoxyribose-phosphate-aldolase
MADAGLSGGSAATGYPRRMEISRDALARMIDHTLLRTDATPAQVSALVAEARELGVFSVCVSPSMLPLTDDLASLKVATVCGFPSGNHTPVTKAAEAAESSRLGADEIDMVINIGYLKAGEPHRVVEEIAAVREATTGTLKVIIESAALTDEEIVTACRAAEEAGADFVKTSTGFHPAGGASTHAVALMAATVNGRLGVKASGGIRDWATAQEMVAAGATRLGVSASRAILEGAPA
>LR134535.1|VEJ59786.1|2992269_2992776_+|Predicted-acetyltransferase
MRTPRLVADDLVLEAPDVADAEDWSDAQDDECARWFGWPCRPGVERCRTHLERVANDAEPGSFTWAIRVPAGFAGGADLKLHEGRWNVSYFVHPAHRGRGIATRALRLVCGWAFDGLGLDVVSTRVRAGNAASLRVLAKVGFRPAGEETGDDGHVEVLHELAGSTHRA
>LR134535.1|VEJ59787.1|2992789_2994625_-|Lipid-A-export-ATP-binding/permease-protein-MsbA
MLSPLARDHSVLQHHFPRGTARRVLAQARPFKGWFIVFAVAVLGGSATTVIPMLLFQRIIDDGVLAGNTGLVVQLALVVAGLALVGMGLGLLERWCSARIGEGLTHRLRCQLFDRVNSMPLAFFTRSSTGRLVSRIVGDVAGAQQAFTSTFSQALSNATTLLLVLGSMLLLSWQLTLAALVLLPVFLVPAKLVARRTARLARLRMDHQAQLTEIMTERFTVSGAMLVKLFGNPRRESRMFEAQAGQLARDGVQMAMTVRIFLSTLTLAGALATAVFYGLGGNAVIGGQLSLGTLTAMVALLARLYGPLTQLSNLRIDLMTAMVSFERVFEVLDLKPSIYDAHDSINVPGPPSIEFDKVWFTYPTASEVSLPSLTSEAEREQKRGGKVLSEISFYVEPGQTVALVGPSGAGKTTITHLVARLYEVEYGAVRVGGADVRGLKQASLRNTVGYVTQDAHLFHDTIRANLQYAMPKAEEQQLWEALEGAQLADLVRGLPDGLDTVVGERGYRLSGGERQRLAIARLLLKSPPVIILDEATAHLDSTSERLVQQALDVARQGRTAIVVAHRLSTVRSADLILVLENGRITERGTHDELLAADGAYARLYQHQFDAS
>LR134535.1|VEJ59788.1|2994689_2995259_-|Uncharacterised-protein
MVRIASVVEGHGEVEALPVLIRRICEEQGEYGHEVGKPHRIHRPEMHTPKVLAAVRIQRARVGESGIVVVLYDADDDEWEAAKKSTQEQLGQERAVIAVAVREYEAWFLAALESLGESRAIKQGARFDADPEQPRNAKKQLELHMTESYRETLHQPKFSALMDLDLLRRRSPSYGRFEDDLAAALKLSR
>LR134535.1|VEJ59789.1|2995252_2996431_-|recombination-protein-F
MSPDTMFRLHRLRLKNYRSIKICNLSLGPLTLLVGPNGSGKSNVLDALRFTSQALGENLDNALRERGGIAEVRRRSTGHPTHFTIAMTFVMGAGRQAGEYEFEIGAAKGGEYRVSREMCRIRSGEFGSEDRFFETRAGQLMSSSEERLPRIFPDRLLLVALSGQEPFRQLFDGLASMGVFSPAPEAMRVVQKPDPGDLLRRDASNIASVIERLRRTDLPAKARIEEYLSHIVPGVKAIQRVGVANWETLEFQQEVQGAANPWSFQASSMSDGTLRALGVLVALFAGTGEVMSPVGIEEPESALHPAASGLLLDAIRDASQRRQILVTSHSPDLLDSPSITVDELLAVRSVSGTTVVDRPDAAAQVALKESLFTAGELVRADQLQPEIGGVAW
>LR134535.1|VEJ59790.1|2996631_2997207_+|Deoxycytidine-triphosphate-deaminase
MLLSDRDILAEVTEGRIALEPWDPAMLQPSSIDVRLDRFFRVFENHRYPHIDPAEEQPELTRLIEVGDEEAFVLHPGEFVLGSTWEQVSLPATVAARLEGKSSLGRLGLLTHSTAGFIDPGFSGHVTLELSNMATLPVKLWPGMKIGQLCFFRLSSEARHPYGSKEYGSRYQGQRGPTPSRSHLNFHRTKV
>LR134535.1|VEJ59791.1|2997228_2998035_-|Uncharacterized-proteins,-LmbE-homologs
MTDVRVLMFGAHPDDCEFESSGLAALVTRAGGVVRFVSATDGSSGHHEMTGPELVERRRAEARAGAAAVGATVTNLGFTDGWLFPDRALREAVITAIRSFGPHVVVSPRPSDYHPDHRAIATAVQDAGYLLMVPGIVPEAPVPETRPVILHTHDPFTDPRPFRPDVVFDIDAVLERKLDAIMAHESQVREWLPHINGFAAEVPGGEPARTEFLRRREREKINRIAVKFADELRRRHGRVPSAAEAYEISEYGAPADAGRVHELLGILP
>LR134535.1|VEJ59792.1|2998069_2999020_-|Putative-fructokinase
MTNITEPGRIPESRKQFHAPSALAIDIGGTKTAFAWVGADGGIIDSFRVPTPAPETARDEALQQLRGHVRRVRGWHTRFGACIVVRPGLMSYDVVELSPNTPAWEDAALAQLVRDELGEVHIRFENDVRAATYGEMVAGRLRDVDPGLYVNLGTGVAAALVVNGRIVVGAHGAAGEIGYMKPSPVADAVRGDGVPPAPLEELLGGPALGRRASKMLGRAVSPRELFAARDPVSVAFVGETAALISTMLGNLCTLLDPQRIVFGGGLARSFDRWAPVVRSHMAASFPYVPELVVSQHVADGSLFGAAMLCSADLPQR
>LR134535.1|VEJ59793.1|2999039_3000275_-|Uncharacterised-protein
MKHALRILVAALSMSLAMPTPAVAASEEETVSNAYLHLDEAMDEWASPPALRVPSSYHGGFLDFWDNSVTYDNALVIIVYANRKDNTDSLDRARTMGDALLQMQEKDPIGDGRLRNAYGPEHLFDANGVPNIQTWGSASGNQAWAGMALAHLAHVTEDAKYRDGALRIGEWLLRETKDTRGRGGFTGGYRSDGTKIEWKSTEHNIDMVGLFGMLHQLTKDHKWRRARKHARKFVKSMWDKKEERFHIGTKPDGVTINRDEYIPEDVQSWGYLALRSDRYRRALDWNIAHLEVTDDSNPSQPVVGVRFALQIKKEHKGKNDKTVWLEGTAHMALALRVSGKKKHKKRAKVYLDNIHKEQLSGPNADGKGIQANSRIGNSGGDDKNYTSLHTGTTSWYIMAKQELNPFHLAKN
>LR134535.1|VEJ59794.1|3000313_3001354_-|1,5-anhydro-D-fructose-reductase
MTSIKFAIIGLDHWYSAVPLARGLSRHPQTDLPLIVDGDPGRGRALASDLGAEFSTSLDDALQDPGIDAIGAFFSVEQNPGICIRAAEAGKHIVSIKPLARTLEEASAIVRAVERAGVQFIPAESRSRMTDQNQRLFEIVRSGELGRIVSANFVLCGVLPKAWEDSESHGWWVEEDKAPGGGWIDHAIYQIDRLRWLLGAEPVDVIGHVANLRYPQLPVEDYGHAIFTFSDGVVATMENTWTGADGAWRITTTLNGTEGSLAIDTIDAHISVLRPDAGASPSWERLEPLDDDSDLIQPLVDRICGENNSLGTVHDAWRNLAAARAFYDAAASGTRRPVPVLASRNT
>LR134535.1|VEJ59795.1|3001429_3002611_-|Fructokinase
MPTASDRLMGKGPKLIREMNQRVLFDSLLSQGPSTRPELARASGLSQPTVIAALNELVDARLVVPLGNDARDTGRPAKLYQVNPAAASVIAVDIGRVWVRVAVVDIAGDELYRHDVRNVARSATALVELISAEVSQAKAKLLLDPGRTYAVIGSPGVFAPKRGVVDYADQLPGWHRPKLINMLNDELGAQLQIENDVNLAALAESIHGQARRHESFAYFHIGTGAGLATILNGKLHRGFHGAAGELAYLLTATGVDGRARVLEDVVSARALTASARELGLVNPTPEAVLQLAAAGDPTARQVMDRFVEGISAAVIAINAVLDPECVVLGGGIGIRLQDYVAEISGAVTRRSPFHVDLEVATLRTDATLRGAVDMGLETARNAMFRLGVPDDLG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	LR134535.1	191924-191960	0	1.0

1. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to position: 191924-191960, mismatch: 0, identity: 1.0

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccagcggcgcggcggcgagcagggcg	Protospacer
*************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134535_9	9.2\|2900082\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2900082-2900119	38	MF140401	Arthrobacter phage Caterpillar, complete genome	19753-19790	4	0.895
LR134535_9	9.2\|2900082\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2900082-2900119	38	MK814756	Microbacterium phage DizzyRudy, complete genome	17289-17326	5	0.868
LR134535_9	9.2\|2900082\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2900082-2900119	38	MN234221	Arthrobacter phage Shepard, complete genome	20758-20795	5	0.868
LR134535_9	9.2\|2900082\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2900082-2900119	38	MH450125	Arthrobacter phage MediumFry, complete genome	19755-19792	5	0.868
LR134535_9	9.2\|2900082\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2900082-2900119	38	MN234186	Arthrobacter phage Egad, complete genome	17670-17707	7	0.816
LR134535_9	9.2\|2900082\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2900082-2900119	38	MN234202	Arthrobacter phage Salk, complete genome	17669-17706	7	0.816
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NC_005241	Cupriavidus necator H16 megaplasmid pHG1, complete sequence	237865-237901	8	0.784
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP039289	Cupriavidus necator H16 plasmid pHG1, complete sequence	237864-237900	8	0.784
LR134535_9	9.122\|2908886\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2908886-2908922	37	NC_009467	Acidiphilium cryptum JF-5 plasmid pACRY01, complete sequence	39374-39410	8	0.784
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	NC_013860	Azospirillum sp. B510 plasmid pAB510f, complete sequence	163017-163047	8	0.742
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	MF189176	Arthrobacter phage Jordan, complete genome	14102-14132	8	0.742
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	MF189178	Arthrobacter phage Shade, complete genome	14081-14111	8	0.742
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	MT889388	Arthrobacter phage Pippa, complete genome	14134-14164	8	0.742
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	MT114161	Arthrobacter phage JKerns, complete genome	14132-14162	8	0.742
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	NC_041933	Arthrobacter phage Sonny, complete genome	14102-14132	8	0.742
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	NC_049468	Arthrobacter phage Zartrosa, complete genome	14105-14135	8	0.742
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	NZ_CP030127	Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence	333316-333346	8	0.742
LR134535_4	4.6\|394727\|32\|LR134535\|CRISPRCasFinder,CRT	394727-394758	32	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	1747704-1747735	9	0.719
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1268086-1268122	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1355417-1355453	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1322572-1322608	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1193018-1193054	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_LR134465	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence	115205-115241	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1099459-1099495	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	743442-743478	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1355424-1355460	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1192115-1192151	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1225051-1225087	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1225042-1225078	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1602918-1602954	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1193010-1193046	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1192366-1192402	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1193001-1193037	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1602860-1602896	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	1281325-1281361	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1090464-1090500	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1268205-1268241	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1268188-1268224	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1268181-1268217	9	0.757
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP019465	Streptomyces autolyticus strain CGMCC0516 plasmid unnamed8, complete sequence	9508-9544	9	0.757
LR134535_9	9.69\|2904983\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2904983-2905020	38	NZ_CP022081	Burkholderia cepacia strain FDAARGOS_345 plasmid unnamed1, complete sequence	174457-174494	9	0.763
LR134535_9	9.69\|2904983\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2904983-2905020	38	NZ_CP012984	Burkholderia cepacia ATCC 25416 strain UCB 717 plasmid pBC25416	121293-121330	9	0.763
LR134535_9	9.69\|2904983\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2904983-2905020	38	NZ_CP009547	Burkholderia sp. 2002721687 plasmid pBTU, complete sequence	110703-110740	9	0.763
LR134535_9	9.69\|2904983\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2904983-2905020	38	NZ_CP034556	Burkholderia cepacia ATCC 25416 plasmid unnamed1, complete sequence	20303-20340	9	0.763
LR134535_9	9.69\|2904983\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2904983-2905020	38	NZ_CP023519	Burkholderia cepacia strain FDAARGOS_388 plasmid unnamed1, complete sequence	150716-150753	9	0.763
LR134535_9	9.69\|2904983\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2904983-2905020	38	NZ_CP013381	Burkholderia sp. Bp5365 strain MSMB43 plasmid pMSMB43, complete sequence	7149-7186	9	0.763
LR134535_9	9.69\|2904983\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2904983-2905020	38	NZ_CP007745	Burkholderia cepacia ATCC 25416 plasmid unnamed, complete sequence	174631-174668	9	0.763
LR134535_9	9.94\|2906828\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2906828-2906865	38	LN997843	Streptomyces reticuli genome assembly TUE45, plasmid : II	787841-787878	9	0.763
LR134535_10	10.3\|2991402\|32\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991402-2991433	32	NZ_CP019641	Planococcus sp. Y42 plasmid unnamed1, complete sequence	232966-232997	9	0.719
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	NZ_CP022365	Azospirillum sp. TSH58 plasmid TSH58_p06, complete sequence	143340-143370	9	0.71
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	NZ_CP012915	Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence	876573-876603	9	0.71
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	NZ_CP032340	Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence	1255800-1255830	9	0.71
LR134535_10	10.6\|2991608\|32\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991608-2991639	32	NZ_CP045361	Roseivivax sp. THAF40 plasmid pTHAF40_a, complete sequence	50743-50774	9	0.719
LR134535_10	10.6\|2991608\|32\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991608-2991639	32	NZ_CP045319	Roseivivax sp. THAF197b plasmid pTHAF197b_a, complete sequence	168843-168874	9	0.719
LR134535_10	10.9\|2991823\|32\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991823-2991854	32	NZ_CP014328	Halocynthiibacter arcticus strain PAMC 20958 plasmid unnamed, complete sequence	38184-38215	9	0.719
LR134535_4	4.2\|394436\|36\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	394436-394471	36	NZ_CP029986	Sphingomonas sp. FARSPH plasmid p01, complete sequence	27074-27109	10	0.722
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	MT711888	Pseudomonas phage Dolphis, complete genome	8041-8071	10	0.677
LR134535_10	10.5\|2991540\|31\|LR134535\|PILER-CR,CRISPRCasFinder,CRT	2991540-2991570	31	NC_004574	Ruegeria sp. PR1b plasmid pSD25, complete sequence	94087-94117	10	0.677
LR134535_6	6.18\|669760\|35\|LR134535\|CRT,PILER-CR,CRISPRCasFinder	669760-669794	35	NC_042034	Mycobacterium phage ChrisnMich, complete sequence	9128-9162	11	0.686
LR134535_9	9.37\|2902656\|38\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902656-2902693	38	NZ_CP035002	Rhizobium acidisoli strain FH23 plasmid pRapFH23d, complete sequence	669271-669308	11	0.711
LR134535_9	9.127\|2909257\|40\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2909257-2909296	40	CP027479	Pseudomonas koreensis strain P19E3 plasmid p2, complete sequence	188016-188055	11	0.725
LR134535_6	6.22\|670049\|36\|LR134535\|CRT,PILER-CR,CRISPRCasFinder	670049-670084	36	NC_003903	Streptomyces coelicolor A3(2) plasmid SCP1, complete sequence	23810-23845	12	0.667
LR134535_6	6.22\|670049\|36\|LR134535\|CRT,PILER-CR,CRISPRCasFinder	670049-670084	36	NC_003903	Streptomyces coelicolor A3(2) plasmid SCP1, complete sequence	332179-332214	12	0.667
LR134535_9	9.12\|2900816\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2900816-2900852	37	NZ_CP054022	Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence	580064-580100	12	0.676
LR134535_9	9.40\|2902874\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2902874-2902910	37	NZ_CP020385	Rhodovulum sp. MB263 plasmid pRSMBA, complete sequence	15752-15788	12	0.676
LR134535_9	9.122\|2908886\|37\|LR134535\|CRISPRCasFinder,CRT,PILER-CR	2908886-2908922	37	NC_010625	Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence	1115830-1115866	12	0.676

1. spacer 9.2|2900082|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to MF140401 (Arthrobacter phage Caterpillar, complete genome) position: , mismatch: 4, identity: 0.895

aacacctacgctgacaagaccatctacaacttcaccga	CRISPR spacer
aacacctactctgacaagaccatctacaacttcggtga	Protospacer
********* ***********************. .**

2. spacer 9.2|2900082|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to MK814756 (Microbacterium phage DizzyRudy, complete genome) position: , mismatch: 5, identity: 0.868

aacacctacgctgacaagaccatctacaacttcaccga	CRISPR spacer
aatacctacgccgacaagaccatctacaacttcggtga	Protospacer
**.********.*********************. .**

3. spacer 9.2|2900082|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to MN234221 (Arthrobacter phage Shepard, complete genome) position: , mismatch: 5, identity: 0.868

aacacctacgctgacaagaccatctacaacttcaccga	CRISPR spacer
aacacttactctgacaagaccatctacaacttcggtga	Protospacer
*****.*** ***********************. .**

4. spacer 9.2|2900082|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to MH450125 (Arthrobacter phage MediumFry, complete genome) position: , mismatch: 5, identity: 0.868

aacacctacgctgacaagaccatctacaacttcaccga	CRISPR spacer
aacacctactctgacaagaccatctataacttcggtga	Protospacer
********* ****************.******. .**

5. spacer 9.2|2900082|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to MN234186 (Arthrobacter phage Egad, complete genome) position: , mismatch: 7, identity: 0.816

aacacctacgctgacaagaccatctacaacttcaccga	CRISPR spacer
aaccattactctgacaagaccatctacaacttcggtga	Protospacer
***  .*** ***********************. .**

6. spacer 9.2|2900082|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to MN234202 (Arthrobacter phage Salk, complete genome) position: , mismatch: 7, identity: 0.816

aacacctacgctgacaagaccatctacaacttcaccga	CRISPR spacer
aaccattactctgacaagaccatctacaacttcggtga	Protospacer
***  .*** ***********************. .**

7. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NC_005241 (Cupriavidus necator H16 megaplasmid pHG1, complete sequence) position: , mismatch: 8, identity: 0.784

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
gggcaggacggccagcagcgcggcggcgagcaggggc	Protospacer
** **  .** *****.******************

8. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039289 (Cupriavidus necator H16 plasmid pHG1, complete sequence) position: , mismatch: 8, identity: 0.784

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
gggcaggacggccagcagcgcggcggcgagcaggggc	Protospacer
** **  .** *****.******************

9. spacer 9.122|2908886|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NC_009467 (Acidiphilium cryptum JF-5 plasmid pACRY01, complete sequence) position: , mismatch: 8, identity: 0.784

gccgcgaa--gcggcgctggacgagctcaacgtccactt	CRISPR spacer
--cgctgactgcggcgctggacgagatcgacgtccaact	Protospacer
  *** .*  *************** **.******* .*

10. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NC_013860 (Azospirillum sp. B510 plasmid pAB510f, complete sequence) position: , mismatch: 8, identity: 0.742

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
ttcaccatcttcggcacgacgctgaaggcgg	Protospacer
.  * ** *********** *********

11. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to MF189176 (Arthrobacter phage Jordan, complete genome) position: , mismatch: 8, identity: 0.742

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
ggcgacggcttcggctcgaagctgaagggcg	Protospacer
 * .**.******** ************ .

12. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to MF189178 (Arthrobacter phage Shade, complete genome) position: , mismatch: 8, identity: 0.742

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
ggcgacggcttcggctcgaagctgaagggcg	Protospacer
 * .**.******** ************ .

13. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to MT889388 (Arthrobacter phage Pippa, complete genome) position: , mismatch: 8, identity: 0.742

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
ggcgacggcttcggctcgaagctgaagggcg	Protospacer
 * .**.******** ************ .

14. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to MT114161 (Arthrobacter phage JKerns, complete genome) position: , mismatch: 8, identity: 0.742

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
ggcgacggcttcggctcgaagctgaagggcg	Protospacer
 * .**.******** ************ .

15. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NC_041933 (Arthrobacter phage Sonny, complete genome) position: , mismatch: 8, identity: 0.742

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
ggcgacggcttcggctcgaagctgaagggcg	Protospacer
 * .**.******** ************ .

16. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NC_049468 (Arthrobacter phage Zartrosa, complete genome) position: , mismatch: 8, identity: 0.742

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
ggcgacggcttcggctcgaagctgaagggcg	Protospacer
 * .**.******** ************ .

17. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030127 (Indioceanicola profundi strain SCSIO 08040 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
cggaacggcttcggcaggaagcttatccggt	Protospacer
******.********* ****** *     *

18. spacer 4.6|394727|32|LR134535|CRISPRCasFinder,CRT matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 9, identity: 0.719

tcgcctcgttcatggattcgatcacgctctcc	CRISPR spacer
taaaactcttcatggcttcgatcacgccctcc	Protospacer
* .  .. ******* ***********.****

19. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

20. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

21. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

22. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

23. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR134465 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 23, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
cccacccgcgcccagcggcgcgccggccagcagtacc	Protospacer
  *  ***************** **** ***** .*

24. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

25. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

26. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

27. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

28. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

29. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

30. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

31. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

32. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

33. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

34. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

35. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

36. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

37. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

38. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

39. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ggccaccgcgcccatcggcacggcggcgttgttgatg	Protospacer
************** ****.********     *..*

40. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP019465 (Streptomyces autolyticus strain CGMCC0516 plasmid unnamed8, complete sequence) position: , mismatch: 9, identity: 0.757

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
ccgcgcggagcccaccggcgcggcggcgcgcagggcc	Protospacer
   *.* * ***** ************* *******

41. spacer 9.69|2904983|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022081 (Burkholderia cepacia strain FDAARGOS_345 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.763

cgcgctgctcgcgttcgccgtccacgacc---ccgagtgcg	CRISPR spacer
gacgctgctcgcgttcgccggccactaccgcttcgagc---	Protospacer
 .****************** **** ***   .****.

42. spacer 9.69|2904983|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012984 (Burkholderia cepacia ATCC 25416 strain UCB 717 plasmid pBC25416) position: , mismatch: 9, identity: 0.763

cgcgctgctcgcgttcgccgtccacgacc---ccgagtgcg	CRISPR spacer
gacgctgctcgcgttcgccggccactaccgcttcgagc---	Protospacer
 .****************** **** ***   .****.

43. spacer 9.69|2904983|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009547 (Burkholderia sp. 2002721687 plasmid pBTU, complete sequence) position: , mismatch: 9, identity: 0.763

cgcgctgctcgcgttcgccgtccacgacc---ccgagtgcg	CRISPR spacer
gacgctgctcgcgttcgccggccactaccgcttcgagc---	Protospacer
 .****************** **** ***   .****.

44. spacer 9.69|2904983|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP034556 (Burkholderia cepacia ATCC 25416 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.763

cgcgctgctcgcgttcgccgtccacgacc---ccgagtgcg	CRISPR spacer
gacgctgctcgcgttcgccggccactaccgcttcgagc---	Protospacer
 .****************** **** ***   .****.

45. spacer 9.69|2904983|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023519 (Burkholderia cepacia strain FDAARGOS_388 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.763

cgcgctgctcgcgttcgccgtccacgacc---ccgagtgcg	CRISPR spacer
gacgctgctcgcgttcgccggccactaccgcttcgagc---	Protospacer
 .****************** **** ***   .****.

46. spacer 9.69|2904983|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013381 (Burkholderia sp. Bp5365 strain MSMB43 plasmid pMSMB43, complete sequence) position: , mismatch: 9, identity: 0.763

cgcgctgctcgcgttcgccgtccacgacc---ccgagtgcg	CRISPR spacer
gacgctgctcgcgttcgccggccactaccgcttcgagc---	Protospacer
 .****************** **** ***   .****.

47. spacer 9.69|2904983|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP007745 (Burkholderia cepacia ATCC 25416 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.763

cgcgctgctcgcgttcgccgtccacgacc---ccgagtgcg	CRISPR spacer
gacgctgctcgcgttcgccggccactaccgcttcgagc---	Protospacer
 .****************** **** ***   .****.

48. spacer 9.94|2906828|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to LN997843 (Streptomyces reticuli genome assembly TUE45, plasmid : II) position: , mismatch: 9, identity: 0.763

gtcacctcgcccgccacggcatcacccccaccagtccc	CRISPR spacer
gcctggacgcccgccaccgcatcaccctcaccagccgc	Protospacer
*.*    ********** *********.******.* *

49. spacer 10.3|2991402|32|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP019641 (Planococcus sp. Y42 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gaagctggatagatccattcgatacggtcaat	CRISPR spacer
ttagaattatagatccattcgattcgttcaac	Protospacer
  **    *************** ** ****.

50. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022365 (Azospirillum sp. TSH58 plasmid TSH58_p06, complete sequence) position: , mismatch: 9, identity: 0.71

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
gggatcagcttcggcgcgaagctgcacttcc	Protospacer
 *** **********.******** *  ...

51. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012915 (Azospirillum brasilense strain Sp 7 plasmid ABSP7_p1, complete sequence) position: , mismatch: 9, identity: 0.71

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
accggcggctccggcaagaagctgaaggctg	Protospacer
   ..*.***.***** *************

52. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032340 (Azospirillum brasilense strain MTCC4038 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.71

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
accggcggctccggcaagaagctgaaggctg	Protospacer
   ..*.***.***** *************

53. spacer 10.6|2991608|32|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045361 (Roseivivax sp. THAF40 plasmid pTHAF40_a, complete sequence) position: , mismatch: 9, identity: 0.719

agagcccgcccagtaaaatccgctgtgtagat	CRISPR spacer
tgagcgcgcccagtgaaatccgctgcatctga	Protospacer
 **** ********.**********..*  .

54. spacer 10.6|2991608|32|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045319 (Roseivivax sp. THAF197b plasmid pTHAF197b_a, complete sequence) position: , mismatch: 9, identity: 0.719

agagcccgcccagtaaaatccgctgtgtagat	CRISPR spacer
tgagcgcgcccagtgaaatccgctgcatctga	Protospacer
 **** ********.**********..*  .

55. spacer 10.9|2991823|32|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014328 (Halocynthiibacter arcticus strain PAMC 20958 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.719

ttcagataacgttttttaacgttacctgtgaa	CRISPR spacer
caaagataacgttattaaacgttaccactgtt	Protospacer
.  ********** ** *********  **

56. spacer 4.2|394436|36|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029986 (Sphingomonas sp. FARSPH plasmid p01, complete sequence) position: , mismatch: 10, identity: 0.722

cgaaggcgcagctgcttcaggtagcgcttcttgaca	CRISPR spacer
gcgcggcgcagctgcttcaggtaacgcctcacgatc	Protospacer
  . *******************.***.** .**.

57. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to MT711888 (Pseudomonas phage Dolphis, complete genome) position: , mismatch: 10, identity: 0.677

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
tatctgagcatcggcacgatgctgaaggccc	Protospacer
..    *** ********* *********..

58. spacer 10.5|2991540|31|LR134535|PILER-CR,CRISPRCasFinder,CRT matches to NC_004574 (Ruegeria sp. PR1b plasmid pSD25, complete sequence) position: , mismatch: 10, identity: 0.677

cggaacagcttcggcacgaagctgaaggctt	CRISPR spacer
gagaacagcttcggcacgctgctgatccgcc	Protospacer
 .****************  *****    ..

59. spacer 6.18|669760|35|LR134535|CRT,PILER-CR,CRISPRCasFinder matches to NC_042034 (Mycobacterium phage ChrisnMich, complete sequence) position: , mismatch: 11, identity: 0.686

gcccgggcggcagaactgatcggcaccaccgccaa	CRISPR spacer
attacggcggcagagctgatcggcaccaccatggt	Protospacer
...  *********.***************.. .

60. spacer 9.37|2902656|38|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP035002 (Rhizobium acidisoli strain FH23 plasmid pRapFH23d, complete sequence) position: , mismatch: 11, identity: 0.711

gcagccatccgctcttcccggtatcgccgcagatagat	CRISPR spacer
gtcgccacccgctcttcccgatatcgccgccaaggatc	Protospacer
*. ****.************.********* .* .. .

61. spacer 9.127|2909257|40|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to CP027479 (Pseudomonas koreensis strain P19E3 plasmid p2, complete sequence) position: , mismatch: 11, identity: 0.725

atccccccacatccgcgagatccagcccgaacccgaaccg	CRISPR spacer
atgcccccacatcagcgagatccagcccatcaccgccaga	Protospacer
** ********** **************.   ***    .

62. spacer 6.22|670049|36|LR134535|CRT,PILER-CR,CRISPRCasFinder matches to NC_003903 (Streptomyces coelicolor A3(2) plasmid SCP1, complete sequence) position: , mismatch: 12, identity: 0.667

cttcaccgcctccagggcggcgttacggcggttcgt	CRISPR spacer
gcggtccgcttccagggcggcggtacggcggcggtc	Protospacer
 .   ****.************ ********.   .

63. spacer 6.22|670049|36|LR134535|CRT,PILER-CR,CRISPRCasFinder matches to NC_003903 (Streptomyces coelicolor A3(2) plasmid SCP1, complete sequence) position: , mismatch: 12, identity: 0.667

cttcaccgcctccagggcggcgttacggcggttcgt	CRISPR spacer
gcggtccgcttccagggcggcggtacggcggcggtc	Protospacer
 .   ****.************ ********.   .

64. spacer 9.12|2900816|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP054022 (Rhizobium sp. JKLM12A2 plasmid pPR12A201, complete sequence) position: , mismatch: 12, identity: 0.676

acgaggatgaggcgtggcctcatgtcgagaccttggc	CRISPR spacer
ttcggccggaggcgtggaatcatgtcgagaccttcag	Protospacer
 . .*   *********  *************** .

65. spacer 9.40|2902874|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020385 (Rhodovulum sp. MB263 plasmid pRSMBA, complete sequence) position: , mismatch: 12, identity: 0.676

ggccaccgcgcccagcggcgcggcggcgagcagggcg	CRISPR spacer
catcacctctcccagcggcgcggcggcgaagaccagc	Protospacer
 ..**** * *******************. *  .

66. spacer 9.122|2908886|37|LR134535|CRISPRCasFinder,CRT,PILER-CR matches to NC_010625 (Paraburkholderia phymatum STM815 plasmid pBPHY01, complete sequence) position: , mismatch: 12, identity: 0.676

gccgcgaagcggcgctggacgagctcaacgtccactt	CRISPR spacer
aaatggaagcggcgctcgacgtgctcaacgtgttccg	Protospacer
.    *********** **** ********* . *.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1926405 : 1977266

Streptococcus_phage(18.18%)

tRNA,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEJ58849.1\|1926405_1927677_+\|tRNA	Glutamyl-tRNA reductase	NA	NA	NA	NA
VEJ58850.1\|1927673_1928753_+	Ferrochelatase	NA	NA	NA	NA
VEJ58851.1\|1928724_1929438_+	putative heme peroxidase	NA	NA	NA	NA
VEJ58852.1\|1929532_1931158_-	Porphobilinogen deaminase	NA	NA	NA	NA
VEJ58853.1\|1931230_1931968_-	Uncharacterised protein	NA	NA	NA	NA
VEJ58854.1\|1932033_1932606_+	transcriptional repressor BetI	NA	NA	NA	NA
VEJ58855.1\|1932577_1933963_-	Uncharacterised protein	NA	NA	NA	NA
VEJ58856.1\|1934273_1935119_+	Glyoxal reductase	A0A2H4PQR8	Staphylococcus_phage	3.6e-49	39.6
VEJ58857.1\|1935360_1935975_-	Predicted acetyltransferase	NA	NA	NA	NA
VEJ58858.1\|1936108_1937341_-	Uncharacterised protein	NA	NA	NA	NA
VEJ58859.1\|1937378_1940768_-	Protein of uncharacterised function (DUF499)	NA	NA	NA	NA
VEJ58860.1\|1940808_1941912_-	Uncharacterized conserved protein	Q9JMP5	Wolbachia_phage	1.1e-34	33.1
VEJ58861.1\|1941915_1942884_-	Uncharacterised protein	NA	NA	NA	NA
VEJ58862.1\|1943393_1944737_-	Protein of uncharacterised function (DUF1156)	K9MDJ7	Sulfolobus_virus	4.7e-19	32.9
VEJ58863.1\|1944733_1948297_-	RNA polymerase-associated protein rapA	A0A1B1IUI1	uncultured_Mediterranean_phage	3.4e-48	27.4
VEJ58864.1\|1948522_1949284_-	Uncharacterised protein	NA	NA	NA	NA
VEJ58865.1\|1949823_1950426_-	Phosphoglyceromutase	NA	NA	NA	NA
VEJ58866.1\|1950422_1950818_-	ribosome-associated protein	NA	NA	NA	NA
VEJ58867.1\|1950804_1951473_-	Probable nicotinate-nucleotide adenylyltransferase	NA	NA	NA	NA
VEJ58868.1\|1951469_1951604_-	Uncharacterised protein	NA	NA	NA	NA
VEJ58869.1\|1951677_1952919_-	Gamma-glutamyl phosphate reductase	A0A1X9I5D4	Streptococcus_phage	8.2e-103	49.4
VEJ58870.1\|1953107_1954175_-	Glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	3.0e-61	41.7
VEJ58871.1\|1954164_1955610_-	GTP-binding protein obg	NA	NA	NA	NA
VEJ58872.1\|1955721_1955979_-	50S ribosomal protein L27	NA	NA	NA	NA
VEJ58873.1\|1955992_1956301_-	50S ribosomal protein L21	NA	NA	NA	NA
VEJ58874.1\|1956934_1959559_-	Ribonuclease G	NA	NA	NA	NA
VEJ58875.1\|1959788_1960976_+	Mannan endo-1,4-beta-mannosidase precursor	NA	NA	NA	NA
VEJ58876.1\|1961096_1961711_+	GDSL-like Lipase/Acylhydrolase	NA	NA	NA	NA
VEJ58877.1\|1961749_1963081_-	Folylpolyglutamate synthase	NA	NA	NA	NA
VEJ58878.1\|1963110_1963668_+	Methylamine utilisation protein MauE	NA	NA	NA	NA
VEJ58879.1\|1963679_1964474_+	Protein-disulfide isomerase	NA	NA	NA	NA
VEJ58880.1\|1964579_1967138_+\|tRNA	Valine--tRNA ligase	A0A2K9KZB8	Tupanvirus	9.8e-159	37.1
VEJ58881.1\|1967200_1967779_-\|protease	Tricorn protease homolog 1	NA	NA	NA	NA
VEJ58882.1\|1967775_1970406_-\|protease	Tricorn protease homolog 1	NA	NA	NA	NA
VEJ58883.1\|1970441_1971725_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	8.4e-135	57.3
VEJ58884.1\|1971820_1972429_-\|protease	ATP-dependent Clp protease proteolytic subunit 1	A0A248SJ97	Salicola_phage	1.1e-31	39.2
VEJ58885.1\|1972425_1973058_-\|protease	ATP-dependent Clp protease proteolytic subunit 2	A0A223W000	Agrobacterium_phage	2.9e-43	48.9
VEJ58886.1\|1973100_1974267_-	pheromone autoinducer 2 transporter	NA	NA	NA	NA
VEJ58887.1\|1974271_1975714_-	Trigger factor	NA	NA	NA	NA
VEJ58888.1\|1975784_1977266_+\|protease	ATP-dependent zinc metalloprotease FtsH	R4TQL5	Phaeocystis_globosa_virus	1.3e-33	38.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134535

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection