CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134375	Veillonella dispar strain NCTC11831 genome assembly, chromosome: 1	3 crisprs	DEDDh,cas3,WYL,csa3,cas2,cas1,csm6,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134375_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134375_1

2058251-2059213

TypeIII

Consensus_repeat	Method
GTTTCCGTCCCCTAATGGGGATTATTTAATTTAAC	CRISPRCasFinder
GTTTCCGTCCCCNNNNGGGGATTATTTAATTTAAC	CRT
AGTTTCCGTCCCCTAATGGGGATTATTTAATTTAAC	PILER-CR

12 spacers

cas2,cas1,csm6,cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10

The CRISPR arrays of LR134375_1

>merge|LR134375|1|2058251-2059213|CRISPRCasFinder,CRT,PILER-CR
TTTAAATACCCCTATGGGGGATTATTTAATTTAACCATTATACGAGGGCGAGCTCGAATATGAAAACCGCTTACTTGAGTTTCCATCCCCTAATGGGGATTATTTAATTTAACGAAAGCGAGGTCTATTATGACACGTCAAAACGAATGGAAGTTTCCGTCCCCTAATGGGGATTATTTAATTTAACTGAACGCTTGGTCCTTGTTTGAACACACTATTCCTGAGAACGTGTTTCCGTCCCCTAATGGGGATCATTTAATTTAACAAGAAATAGCCGGACTAGAAACCGAAATAAATGCGGTTAATTGTTTCCGTTCCCTAATGGGGATTATTTAATTTAACGCGTTGAAGAGTTGAATTGTAATGAATTAATTGAGTACATAAAGTTTCCGTCCCCATCAGGGGATTATTTAATTTAACTACTTATAGAATATAAATCACATGAATTAGAGTTTGAACATGAGTTTCCGTCCCCTATTGGGGAGTATTTAATTTAACTTTCAAAAAAAAGAAAGCCATATACACCGACTGCAATCGACAGTTTCCGTCCCCTAATGGGGGTTATTTAATTTAACACAATTCATCCACTCTATTAGTATCGCTGATGACCATGTATGGTTTCCGTTCCCTAATGGGGATTATTTAATTTAACGGTAACTAAAATCGCAACTATAAAAAAATCTATTGATACTAAGTTTCCGTCCCCATCAGGGGATTATTTAATTTAACTGATCTCAATGCCAAATCTCTTGGATAATATGCTCACCTTATCGTTTCCGTCCCCCAATGGGGATTATTTGATTTAATAGAATTGGCTATCAATTCAATATCTTGTTAAATGCAGATGTAGTATTTCCGTCCCCATCAGGGGATAATTTAATTTAACCAAAGAGAGAATGTCTCGCACTAATTTAAATACTATGGCTGAATATCCGCCCCCTTCAGGGGATTATTTAATTTAAC

>LR134375|1|1|2058251-2059213|CRISPRCasFinder
TTTAAATACCCCTATGGGGGATTATTTAATTTAAC	CATTATACGAGGGCGAGCTCGAATATGAAAACCGCTTACTTGA
GTTTCCATCCCCTAATGGGGATTATTTAATTTAAC	GAAAGCGAGGTCTATTATGACACGTCAAAACGAATGGAA
GTTTCCGTCCCCTAATGGGGATTATTTAATTTAAC	TGAACGCTTGGTCCTTGTTTGAACACACTATTCCTGAGAACGT
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	AAGAAATAGCCGGACTAGAAACCGAAATAAATGCGGTTAATT
GTTTCCGTTCCCTAATGGGGATTATTTAATTTAAC	GCGTTGAAGAGTTGAATTGTAATGAATTAATTGAGTACATAAA
GTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	TACTTATAGAATATAAATCACATGAATTAGAGTTTGAACATGA
GTTTCCGTCCCCTATTGGGGAGTATTTAATTTAAC	TTTCAAAAAAAAGAAAGCCATATACACCGACTGCAATCGACA
GTTTCCGTCCCCTAATGGGGGTTATTTAATTTAAC	ACAATTCATCCACTCTATTAGTATCGCTGATGACCATGTATG
GTTTCCGTTCCCTAATGGGGATTATTTAATTTAAC	GGTAACTAAAATCGCAACTATAAAAAAATCTATTGATACTAA
GTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	TGATCTCAATGCCAAATCTCTTGGATAATATGCTCACCTTATC
GTTTCCGTCCCCCAATGGGGATTATTTGATTTAAT	AGAATTGGCTATCAATTCAATATCTTGTTAAATGCAGATGTAGT
ATTTCCGTCCCCATCAGGGGATAATTTAATTTAAC	CAAAGAGAGAATGTCTCGCACTAATTTAAATACTATGGCTGA
ATATCCGCCCCCTTCAGGGGATTATTTAATTTAAC

>LR134375|1|1|2058251-2059213|CRT
TTTAAATACCCCTATGGGGGATTATTTAATTTAAC	CATTATACGAGGGCGAGCTCGAATATGAAAACCGCTTACTTGA
GTTTCCATCCCCTAATGGGGATTATTTAATTTAAC	GAAAGCGAGGTCTATTATGACACGTCAAAACGAATGGAA
GTTTCCGTCCCCTAATGGGGATTATTTAATTTAAC	TGAACGCTTGGTCCTTGTTTGAACACACTATTCCTGAGAACGT
GTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC	AAGAAATAGCCGGACTAGAAACCGAAATAAATGCGGTTAATT
GTTTCCGTTCCCTAATGGGGATTATTTAATTTAAC	GCGTTGAAGAGTTGAATTGTAATGAATTAATTGAGTACATAAA
GTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	TACTTATAGAATATAAATCACATGAATTAGAGTTTGAACATGA
GTTTCCGTCCCCTATTGGGGAGTATTTAATTTAAC	TTTCAAAAAAAAGAAAGCCATATACACCGACTGCAATCGACA
GTTTCCGTCCCCTAATGGGGGTTATTTAATTTAAC	ACAATTCATCCACTCTATTAGTATCGCTGATGACCATGTATG
GTTTCCGTTCCCTAATGGGGATTATTTAATTTAAC	GGTAACTAAAATCGCAACTATAAAAAAATCTATTGATACTAA
GTTTCCGTCCCCATCAGGGGATTATTTAATTTAAC	TGATCTCAATGCCAAATCTCTTGGATAATATGCTCACCTTATC
GTTTCCGTCCCCCAATGGGGATTATTTGATTTAAT	AGAATTGGCTATCAATTCAATATCTTGTTAAATGCAGATGTAGT
ATTTCCGTCCCCATCAGGGGATAATTTAATTTAAC	CAAAGAGAGAATGTCTCGCACTAATTTAAATACTATGGCTGA
ATATCCGCCCCCTTCAGGGGATTATTTAATTTAAC

>LR134375|1|1|2058328-2058515|PILER-CR
AGTTTCCATCCCCTAATGGGGATTATTTAATTTAAC	GAAAGCGAGGTCTATTATGACACGTCAAAACGAATGGA
AGTTTCCGTCCCCTAATGGGGATTATTTAATTTAAC	TGAACGCTTGGTCCTTGTTTGAACACACTATTCCTGAGAACG
TGTTTCCGTCCCCTAATGGGGATCATTTAATTTAAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134375.1\|VEG94499.1\|2065160_2065844_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
LR134375.1\|VEG94493.1\|2059537_2059813_-\|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
LR134375.1\|VEG94496.1\|2062224_2062995_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl\|CDD\|227838
LR134375.1\|VEG94495.1\|2060908_2062228_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm6	csm6	pfam09659_csm6_CAS-III-A	gnl\|CDD\|312974
LR134375.1\|VEG94486.1\|2050082_2051501_+\|Na(+)/glucose-symporter	unknown	unknown	gnl\|CDD\|271357
LR134375.1\|VEG94497.1\|2062984_2064205_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
LR134375.1\|VEG94484.1\|2048795_2049368_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94485.1\|2049662_2049764_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94489.1\|2053453_2054815_-\|Putative-cryptic-C4-dicarboxylate-transporter-DcuD	unknown	unknown	gnl\|CDD\|225611
LR134375.1\|VEG94502.1\|2070125_2071967_-\|Uncharacterized-conserved-protein	unknown	unknown	gnl\|CDD\|377008
LR134375.1\|VEG94488.1\|2052057_2053278_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94494.1\|2059814_2060810_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
LR134375.1\|VEG94500.1\|2065856_2066369_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|367635
LR134375.1\|VEG94490.1\|2054844_2056005_-\|Aminobenzoyl-glutamate-utilization-protein-B	unknown	unknown	gnl\|CDD\|349883
LR134375.1\|VEG94492.1\|2057088_2058129_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94491.1\|2056188_2056875_-\|Acetate-operon-repressor	unknown	unknown	gnl\|CDD\|224332
LR134375.1\|VEG94498.1\|2064152_2065151_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|380071
LR134375.1\|VEG94483.1\|2048217_2048787_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94487.1\|2051798_2051900_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94501.1\|2066379_2068935_-\|Predicted-HD-superfamily-hydrolase	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811

Protein	Function_ID	Function_description	E-value
LR134375.1\|VEG94493.1\|2059537_2059813_-\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.576e-21
LR134375.1\|VEG94496.1\|2062224_2062995_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	0.000882596
LR134375.1\|VEG94495.1\|2060908_2062228_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm6	gnl\|CDD\|312974	pfam09659, Cas_Csm6, CRISPR-associated protein (Cas_Csm6). Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.15229e-41
LR134375.1\|VEG94486.1\|2050082_2051501_+\|Na(+)/glucose-symporter	gnl\|CDD\|271357	cd10322, SLC5sbd, Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain. This family represents the solute-binding domain of SLC5 proteins (also called the sodium/glucose cotransporter family or solute sodium symporter family) that co-transport Na+ with sugars, amino acids, inorganic ions or vitamins. Family members include: the human glucose (SGLT1, 2, 4, 5), chiro-inositol (SGLT5), myo-inositol (SMIT), choline (CHT), iodide (NIS), multivitamin (SMVT), and monocarboxylate (SMCT) cotransporters, as well as Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. Vibrio parahaemolyticus Na(+)/galactose cotransporter (vSGLT) has 13 transmembrane helices (TMs): TM-1, an inverted topology repeat: TMs1-5 and TMs6-10, and TMs 11-12 (TMs numbered to conform to the solute carrier 6 family Aquifex aeolicus LeuT). One member of this family, human SGLT3, has been characterized as a glucose sensor and not a transporter. Members of this family are important in human physiology and disease.	2.18567e-93
LR134375.1\|VEG94497.1\|2062984_2064205_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	4.95403e-18
LR134375.1\|VEG94499.1\|2065160_2065844_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.43444e-71
LR134375.1\|VEG94502.1\|2070125_2071967_-\|Uncharacterized-conserved-protein	gnl\|CDD\|377008	pfam03235, DUF262, Protein of unknown function DUF262.	3.18579e-23
LR134375.1\|VEG94489.1\|2053453_2054815_-\|Putative-cryptic-C4-dicarboxylate-transporter-DcuD	gnl\|CDD\|225611	COG3069, DcuC, C4-dicarboxylate transporter [Energy production and conversion].	1.84697e-98
LR134375.1\|VEG94494.1\|2059814_2060810_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	7.82435e-110
LR134375.1\|VEG94500.1\|2065856_2066369_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	7.39277e-10
LR134375.1\|VEG94490.1\|2054844_2056005_-\|Aminobenzoyl-glutamate-utilization-protein-B	gnl\|CDD\|349883	cd03887, M20_Acy1L2, M20 Peptidase Aminoacylase 1-like protein 2, amidohydrolase family. Peptidase M20 family, Aminoacylase 1-like protein 2 (ACY1L2; amidohydrolase) subfamily. This group contains many uncharacterized proteins predicted as amidohydrolases, including gene products of abgA and abgB that catalyze the cleavage of p-aminobenzoyl-glutamate, a folate catabolite in Escherichia coli, to p-aminobenzoate and glutamate. p-Aminobenzoyl-glutamate utilization is catalyzed by the abg region gene product, AbgT. Aminoacylase 1 (ACY1) proteins are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	1.29795e-150
LR134375.1\|VEG94491.1\|2056188_2056875_-\|Acetate-operon-repressor	gnl\|CDD\|224332	COG1414, IclR, Transcriptional regulator [Transcription].	3.55458e-56
LR134375.1\|VEG94498.1\|2064152_2065151_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm4	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	3.51218e-28
LR134375.1\|VEG94501.1\|2066379_2068935_-\|Predicted-HD-superfamily-hydrolase	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0

>LR134375.1|VEG94492.1|2057088_2058129_-|Uncharacterised-protein
MDVLVSSQLNSVVQSYIGKRIMIVVPSQSVEQGVDAEGSNHLGANSEVESRLATNNQAAAGLPYSYTTGRDWNRHHIPGFVGDNAFGMELMCWSPDRLEDLQEVAAWYVQKYGVHHVLFISLKGEAKILNYDGSRIAGNHKLGPWQAEHIELYGQTLVDDSKNKDGLYQCTSINRDYRLVRAPHCDRSNLEDFGQLFNHLGADHILFVPVIDHKVDGRTMQQYLAFLDVPYDKIHHSFATGENSLYYVLYVRHCRLKLVLDVLQLLFDDSNSKPLLYVTPEGNLYKLRRDMSILQNCGVFSRATYIAMFTKLNKETLQIQLDRDFHYNRPNMFTRMGGAMILGQLK
>LR134375.1|VEG94491.1|2056188_2056875_-|Acetate-operon-repressor
MVQSIERGIEILKLLEAGPLGVTELANATALPKTTVHRLLKTFEAHHWVEFNGAKKYQLSWGVLPMAKSFLTSLDVRAIAQPYMVAIRDQLQQSVNLFLAQGDYRICIERVAADKPLRHDIKIGTVYPIFKGAAGKIFGAYLGDFNDTDMSAGESAQIRHDGYVVTRGNRVPDAASIAVPIFSFGNKLEAVMTISGPIGDYTEERVKEYLSVVMALGQTISKQMGATL
>LR134375.1|VEG94490.1|2054844_2056005_-|Aminobenzoyl-glutamate-utilization-protein-B
MSQLLQEIEALRQPMKELNDFIFDHPELGNEEFQAHELLTNLLEKEGFTVDREVSGLKTAFRAVYHVNGGGPKIGLLCEYDALEGLGHACGHNLQGPSICTAAIALKRTLQAPCTLVVYGTPAEETASGKLVMAREGVFDDLDLAFMMHGSDTTTVDGKSLALNLVNIKFHGKSAHAAIAPEKGISALDAVLLFFNGMEYLREHVPTEVRMHGIITDGGKAANIVPDYACTQWYIRSSSRIRLNEIVERVKNVAQGAALQVGATMEWEEVKAYDNKVNVQTLNDILLKNAEKVGAPEISEPRKVTGSTDFSSVTFRVPGACLRVKFVGKGVTSHSQEWLDNGKSQLAEYAIMYGAKGIALSVEEILETPGLLEKIKEDFKQAKENF
>LR134375.1|VEG94489.1|2053453_2054815_-|Putative-cryptic-C4-dicarboxylate-transporter-DcuD
MNLLVCLLVIVITGTLVIKKFKAQTVLLLGGLIMMFAAYLLGYTTSFVEAKKATGVLFFDAFEFINITTAKDAANLGLMIMTCTGFAKYMDHIGASSRLVVTAIKPLGKMKSAYLVMALTFILNMFMSLVIPSASGLAMLMMVTIFPILVRLGVSPVGAAAAVATGHLLDIGPASATTLLVSKTVNMPVHEYFVGYQLKVYIICGLMAAIAHFVWQKYLDKKSGHVPAEYVESHKSDDLEVGPLPYIFLPLLPLIFILGFSDYGIQGVKMNVNLAMFLSLFIAMGCELIRHRDFRKMAASIQTFFKGMGDQFANTVTLIVAGETFAFGLTSLGIVKEFVAAIQGLAISADVVGVIVSTIITGLSIVMGSGVASMFAFAPLVPNFAADLGGNATTILLGMQNAASVGRLLSPISAVMIAVAGIANISSFDLVKRTSVPVIVTFITSTIAILLIH
>LR134375.1|VEG94488.1|2052057_2053278_-|Uncharacterised-protein
MKLKSTLLSLAVALAFTMPINAAQYTVPEGQPPVPGADASIPDNAYQNYRYDKTRNITTADHIKKIEEYNNRIDGEVLKKKGTAEKAEQLKKAYAKYLDLITHESTVILLHEGDYKAKVTLPISVVESYFEDLNKKGKGSYVFEHNVIAGLVGANEQVEDSGFNRNDQRKGEFKYPGISKGYWGIREKYSNGNLPVMYAAVTFDQYPNQMYMAILGNKNQPVTKKLESTMANFVIPSMQTLDNLDKTSDTVTWDNLTYRLPKGMMLDREEKSDNFQGRVYVGDGMKLVVARSALVDKAVPIQLYTQTVLKHFFYKKNPILVKDIPLQAALIWNNGVPSYLLEQYNPGKKSRIFHLITDDKYEYYISLTYEDGKNKYNHIELRNIMEYLDFGNAKQLRHASNKRVKK
>LR134375.1|VEG94487.1|2051798_2051900_-|Uncharacterised-protein
MSGYKIIMIILGILSVMISFGALVALICLEIAK
>LR134375.1|VEG94486.1|2050082_2051501_+|Na(+)/glucose-symporter
MDALTIIWVIVCAYLLLNLLVGVYCHIRVKDSTDYLLAGRRIGVLMTAGTLAATEIGGGSTVGVAAKAYGSWGLSAGWYVVSAGIGVILVAFIAPLLRRAMATTVPEIIGRRFGGSSHLITSILSMLATITLAGVQITATATIISVLTGLSTELAILICGAVLVIYTMSGGMWSVTMTDVIHFFVLVGGFTLAVPFVLHNVGGWETVVSKLPPEQLGFTKVGWKTIIGLIIMYFMTFSTGQESVQRYFAAKNERTAVLGSIICGIIMALFAFVPAVLGLVALAEFPNIEANNAVATVALNLMPPIMAGFVMAAVVSATLSSGAGDLLGAATVFTKDIVEHHFGKSLTDAQLTNYSRLCVLFLGIIAIVISLVSKAIIPMLVFAFTMRSAGPFAAFLLGLTWKNATAGAGIWSIVLGSIAGVYWEFVGNPYGIMSIIFGSIVSLIVFVAVVCIERAMGKPPAPPAIPDDVKEM
>LR134375.1|VEG94485.1|2049662_2049764_-|Uncharacterised-protein
MSDYEIIMLLLQVLAIVIAFGALVALICLTKSK
>LR134375.1|VEG94484.1|2048795_2049368_-|Uncharacterised-protein
MIQRILLLALVLLAFTMPTEAITYQELKTSPQFKLVHTRSMNGSMESGGLYIYLNTYSIEALRYAPPQYSLRGTYYVVMDTSYQSTIDERQLTVDYDTNYSLATLVHSSRIMNPSPSMMALIEASESKSGLAMTEVDVAKYTFDGATKPMHYVNDTRKFPLNRNNTIMYDIADAMFMSVYQQHFDDIVVQ
>LR134375.1|VEG94483.1|2048217_2048787_-|Uncharacterised-protein
MKRIYLLSLWLLGCLIVPMQGQAVSQADLLNAERFEHIDSSADSGRGDGKYLDLSSVKSVTAPNGHRRIEAVIYVSMPAANMIQGLSVQYDYQMDRSLRHLINDHDKSLKQGDKTPYISIWRAKQVNSGITGTVNDGGTYYNNGQTRQQRIYAENLKAMILPAEFGDEKYKLPNLMYKKAYGIAYDDEP
>LR134375.1|VEG94493.1|2059537_2059813_-|CRISPR-associated-endoribonuclease-Cas2
MKKFIVLVIYDVVDNKTRNRLVKCLERYGVRVQKSAFEALLNRKQYDAMMRRASKMINPVEDSLRVYVLDDIINIYTWGIGERKEQDCIVL
>LR134375.1|VEG94494.1|2059814_2060810_-|CRISPR-associated-endonuclease-Cas1
MSSLYVTEAGSFIKRDGGHVVVGRNNEVLFEVPLERIEDITVFDSVSITSSLVTDFIERGVPITWLSGYGKYFGTLINTNTIDINKHKKQFDLLDDNAFRVAMSRKIIRAKVRNQLTILRRYARNLEEDINIDAQIANIKSVRSHIGECMRVSELMGYEGLISRLYFEALGKIVPSAFAFTKRTKQPPRDPFNAMLGLGYSMLFNEILAGVINAGLHPFVGIMHSLAKGHPALASDLIEEWRAPIIDSMVLSMVSRNMVDLAEFDNSDKGCYLTAEGRKVFLTAYNKKIRSENQYIDDRKSYRESIYKQCKQFASAIMHEDVDLYTPLEIH
>LR134375.1|VEG94495.1|2060908_2062228_-|CRISPR-type-III-A/MTUBE-associated-protein-Csm6
MRILYTPVGDTDPIRGCYDGGMLHIVRHYNPDMAILVLSKDMEQKEAANHRFTKALKHVKADLDIKIIHTGLEDVHRIDVLQPFVDHFYETLSTYPDAEILINLSSGTPQMKLIMSYLSVEHDAVRGIQVDSPQRGSNRSEPAVNDDEDIELVIENNFDDQEDSENRCHEPQMGYIKRNNIKQSLHTLITSYKYKEAISSYHSYKRTFESDVVNDVLPLLEHAQLRLGLNYDDALQKARKVGSTSLSSLFTDKELRKLHEFLMLMEVRLKQGQIEDFVLKTTPFMYELMRYYFTKELNVNWRQVEKKTSKGMRLDMVAFKNQYPKLYESWQENSDTPYLQELQVSFYHMLHMLEDYDTVDSSLLKHLKEIRRIERKIRNKIAHEVVVFTEQDICSAAEIQSLQFFLHQIKDVFFIIARQEKQNKLIYDTINKYVLDQIQ
>LR134375.1|VEG94496.1|2062224_2062995_-|CRISPR-associated-endoribonuclease-Cas6
MADNIEIMAIELGITADPSIKIVQSIGSVLHGVLMELVGTEYAGQLHETGLRPYSQYIYFDKEKGQYIWRLSAVTAEAVERILRPVLNMPEKLFLKQKRGHIYIQDRTVLEETSYEALMAKFWSGEAEYTQAKLRCVTTTSFKVDQQYTIFPEAFRIYRYLLRQWNQFTTFEMMDSDDLLSALESAAFIRDYNLRMGMYGLEGIKIRGFRGEIVMQFKRNLVMQRILSLLTYYSQFTGLGIKTALGMGGVQSEVVQ
>LR134375.1|VEG94497.1|2062984_2064205_-|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm5
MLYIVMVWAYGLGWIMSNRIDHAQLLLTVVSPTNIGGPEKLTTKDYMYNYDAGEVYLLNNYEWFRFLARHNKLAEFELYMQDEMVRPNGRTMYDWAKNTVGAAQLTKDALGPVIGSIMKSSIYNKGRKNSLNDITPQIRGANGDVYIPGSSIKGVIDSAIISHMLRNNKAFRSTVQRELKKVLDVYKRKNARNLFKDIFKMVNLVILKHIHVLTNNEGKPFKAILASAFRGLSVSDAMPMGAIQTEVLKKEDSCIDEDGTHAISVHRECILPNQKFSFTVTLDTAMTKEIGITSINQVLDILQEDFDATHKLLASKFKKVSPSIFKALELANAYIGSNTGFVQKTIIMAAFIDDEKTGIDIIKAILDVNFQKAEHDRKDTIMAPRAIKLVKWNGNYYEMGGIHIGR
>LR134375.1|VEG94498.1|2064152_2065151_-|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm4
MNYYIYPLRFLTPVHFGDTSEGGSLETISLTVGSDALFGACCHEISYDTDLLQSFIDSVKDQHIVLSSLFPYCIDNGEYQLYVPSPIMQIDSKEMPITSFAETKRVATEQKKIKKIEYIRASQLQNYNQYIEADTSQKHMPIFGTRQAMTQVNMRGEKSRPYYVGSYQFMSNTGLYIIAGFIDDDSRELFEAILELLGLSGIGGKRSSGYGKFELADDPIELESEGIYEDDSALYTLLHKKYEKMMCISACVPTCDEVATLKQGSYKLQKRGGFVGTARSTTQVKRNSYYVVKEGSICPKELVGQMLTITGDSLPHAVYRNGMGLWIGVDYE
>LR134375.1|VEG94499.1|2065160_2065844_-|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm3
MENNDNLKSLRGKLLITGTIKLETGMHIGASNDFAPIGSVDTPFIRDVVSQEPIIPGSSIKGKLRTLLAKSHCDDYIMNDIKEDKEEIKRLFGSVNPVKPARLQFYDLFITDETRQLFSNIETDTYMGEIKFENTINRVDGSANPRQIERVPAGTVFTFKVAYNIESEDEVIEDMNILKAGLDLLGIDYLGGHGSRGYGRVNISIDDVKSVGNSTINTQDLLDILRK
>LR134375.1|VEG94500.1|2065856_2066369_-|CRISPR-type-III-A/MTUBE-associated-protein-Csm2
MIQGKFNWDIDIVTKAEETIGRLRYNPKCKKTDEVFDVKYAQVRKILSSVVAIKNKLGVEQRKSKSFDKLPDSIAMEVRFLKTTFLYQAGRDKDYKYPIKSFIEDSQLVEMVECIGTDVKKFDMFCKYVEALVAFYKYRAVSVIADTNDTWNKNKPYNNQNYNQSNGNRR
>LR134375.1|VEG94501.1|2066379_2068935_-|Predicted-HD-superfamily-hydrolase
MGKWDALVKGALLHDIGKVVYRANQGTDAHSKRGAAFIEPYFSDMGLKQSITHCLKYHHGKELSAAQLKNDDYAYIVYEADNIAAAVDRRDLDEGESTATQKFNKELPLQSIFRVFGGNTSNKPLQYYLRGIDASDHFNYPENDKTIRASSDKYKALYDVLVQNFQQQPIDKMSVNELLRIYEDTVSYMPSSTATDQANDISLYMHSKITAAVAHSMVHYFEEQEITDYKEYCYQNSKKFRDMPAFRLISGDISGIQNFIYTIPSKGALKSLRGRSFYLEILMEQIVDELLDALQLTRANLIYNGGGHFYILAPNTTKTSTAIETMEKSINEWFLTVFGTKLYLALGSATAAAAELIQSQRALFRKVSQSVGEAKSKRYSEQHLADLFNPNSTYNTVLHGERECSICHTSTVALSPYGKDTDAEACPICNGLYRLGEQIVDGRDTVFVLARPNISDDSESIPKVEVYVNNLSSDADKGKLYLYVVPESLLQKFESSHEILRIYSKNTAKTGHNVFNRIWLADYVARKDNGQVYEFEELAASSGFGDDKGIKRLGVLRADVDNLGAAFIGGFISEGADKFKYGTLSRYADLSRDLAMFFKVAVNKMAQGDVQGFGTSVTPFTIWANKQVTTRKIHVIYSGGDDVFLVGAWDELLELAIDIREKLAEVTDNKITMSAGLALFSPSYPISQMAAITGLLESVAKDNDGKDSIALFGFETNKNASGEERICRHVYKWDDLINNVIEDKIYTLDQLFVIPGINEKQDAKMKLGKGLIYKLMELLQGVLNDRALGKHINVARILYLLARLEPKKNNPTYESYKNFVTAIHRWIQSEEDCKALLTACNLIVYYMRDTK
>LR134375.1|VEG94502.1|2070125_2071967_-|Uncharacterized-conserved-protein
MAEITSLMKDIKGILDNKNQFVIPDFQRSFVWTDKDVDTLFSDFKEDTDNYTDRLDTLPGYLLGNIVLISNENNPTRFDVIDGQQRLTTLTLIFCALNNLFMDIAEETRRNLGANADMWMGHTFSFKEYFRILDNNLQFVDYKILHTQDLDFKETYKSIIKQGALVSDEDNTSANNLEAVYESILQHLRSIYDDEPQKLLYFLQYLTTKVKLIETTAPSIERAFQLFEILNNRGQSLEPLDLLKNYLLKNLTSAPGITQNQIKDFSDSWSQFLKNLKDTGKSKAIETSTFIKHFIIGTKAINVKKKDLFEHFKDNELVANDILQLSSDINSISKVYASINRDPLSNDFLSNDDGMYTLFTLFNTVQIHPLLMPFYNASRVDKVRLVDAAVRYVAAVIFSYTQTNAIEAELPEIIEKILHESDPACRLEVAVTELELRTKPYVDLIRVLLPVKDFGSKNKKQAPKAFQILKFIELYLNQKDSIKTNKKIELEHIMPQAADNADYSFDDEDTRKEYLNHLGNLTLLDKSLNASVKNGNFAEKLDHYKACEFVITRALAEEIDSPVQNQQPLINFQNTYFAVDNPEQITYWDKTQIDERGQKLVEVLEKLLLKQVP

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Crispr_ID: LR134375_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134375_2

2069118-2069915

TypeIII

Consensus_repeat	Method
ATTGGGGGATCATTAAATTTAAC	CRISPRCasFinder

10 spacers

cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6,csm6,cas1,cas2

The CRISPR arrays of LR134375_2

>merge|LR134375|2|2069118-2069915|CRISPRCasFinder
AAATGGGGATTATTTAATTTAACTAGAAAATAAGTGTTGCTTTATTCACCAATATGGTGTATAAATTTCCGTCCCCCAATGGGGATTATTTAATTTAAATGTTATTGGCTTAGAGCATTTGCAGCTTTAATGGCCGTTGGGTTTCCGTCCCCTGTTGGGAATCAATAAATTTAACATGAGAAAACACAGTTTCATGAACAGACATTTCTTAGCGTGTATGTTTCCGTCCCCTAATGGGGATCAATAAATTTAACAGACGACTACAACTATTATTCTTAATTCAAACTTATTTAACTGGTTTCCGTCCCCATTAGGGGATTATTTAACTTAACCAATGGTTAATAATACAACCTATGTGTTCGCTGGTACTGATGTGTTTCCGTCCCCATTAGAGGATTATTTAATTTAACTAGAACAAAACGTTGAGGCATTAACTCAACAAAACGCTATGTTGTTTCCGCCCCCTTATGGGGATTATTTTATTTATCTAGTGAAAGCCAAGAAAATGAGAAAAAACTTAACGCTAATAAATTCCCGTCCCCCATCAGGGGATTAATAAATTTAACTGCAATTAATGGCTTAGGTCAAAAGGTAGCAACAAATACGGCATTTCCGTCCCCTATTGGGGATTATTTAATTTAACACTAGATATTTACATATTGTCTTTCTTATTGGAAAAAAGTTTATTCCGTCCCCTATTGGGGGATCATTAAATTTAACGCAGATGCGTTTTGTTAACACTCATGAACTAAAAGAGTATATAGTTTCCGTCCCCATTAGGGGATCATTAAATTTAAC

>LR134375|2|2|2069118-2069915|CRISPRCasFinder
AAATGGGGATTATTTAATTTAAC	TAGAAAATAAGTGTTGCTTTATTCACCAATATGGTGTATAAATTTCCGTCCCC
CAATGGGGATTATTTAATTTAAA	TGTTATTGGCTTAGAGCATTTGCAGCTTTAATGGCCGTTGGGTTTCCGTCCCC
TGTTGGGAATCAATAAATTTAAC	ATGAGAAAACACAGTTTCATGAACAGACATTTCTTAGCGTGTATGTTTCCGTCCCC
TAATGGGGATCAATAAATTTAAC	AGACGACTACAACTATTATTCTTAATTCAAACTTATTTAACTGGTTTCCGTCCCC
ATTAGGGGATTATTTAACTTAAC	CAATGGTTAATAATACAACCTATGTGTTCGCTGGTACTGATGTGTTTCCGTCCCC
ATTAGAGGATTATTTAATTTAAC	TAGAACAAAACGTTGAGGCATTAACTCAACAAAACGCTATGTTGTTTCCGCCCCC
TTATGGGGATTATTTTATTTATC	TAGTGAAAGCCAAGAAAATGAGAAAAAACTTAACGCTAATAAATTCCCGTCCCCC
ATCAGGGGATTAATAAATTTAAC	TGCAATTAATGGCTTAGGTCAAAAGGTAGCAACAAATACGGCATTTCCGTCCCC
TATTGGGGATTATTTAATTTAAC	ACTAGATATTTACATATTGTCTTTCTTATTGGAAAAAAGTTTATTCCGTCCCCT
ATTGGGGGATCATTAAATTTAAC	GCAGATGCGTTTTGTTAACACTCATGAACTAAAAGAGTATATAGTTTCCGTCCCC
ATTAGGGGATCATTAAATTTAAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134375.1\|VEG94511.1\|2084573_2084945_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94493.1\|2059537_2059813_-\|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
LR134375.1\|VEG94496.1\|2062224_2062995_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl\|CDD\|227838
LR134375.1\|VEG94495.1\|2060908_2062228_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm6	csm6	pfam09659_csm6_CAS-III-A	gnl\|CDD\|312974
LR134375.1\|VEG94501.1\|2066379_2068935_-\|Predicted-HD-superfamily-hydrolase	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
LR134375.1\|VEG94503.1\|2074969_2075578_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94509.1\|2082623_2083667_-\|Protein-involved-in-cell-division	unknown	unknown	gnl\|CDD\|225718
LR134375.1\|VEG94506.1\|2078697_2079843_-\|Beta-hexosaminidase-A-precursor	unknown	unknown	gnl\|CDD\|224389
LR134375.1\|VEG94504.1\|2076054_2076945_-\|RNA-polymerase-sigma-factor,-sigma-70-family	unknown	unknown	gnl\|CDD\|274357
LR134375.1\|VEG94507.1\|2080254_2081685_-\|Iron-hydrogenase-1	unknown	unknown	gnl\|CDD\|274171
LR134375.1\|VEG94499.1\|2065160_2065844_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
LR134375.1\|VEG94502.1\|2070125_2071967_-\|Uncharacterized-conserved-protein	unknown	unknown	gnl\|CDD\|377008
LR134375.1\|VEG94494.1\|2059814_2060810_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
LR134375.1\|VEG94500.1\|2065856_2066369_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|367635
LR134375.1\|VEG94497.1\|2062984_2064205_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
LR134375.1\|VEG94508.1\|2082137_2082512_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94492.1\|2057088_2058129_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94510.1\|2083858_2084224_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94498.1\|2064152_2065151_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|380071
LR134375.1\|VEG94505.1\|2077279_2078344_-\|Predicted-ATPase-(AAA+-superfamily)	unknown	unknown	gnl\|CDD\|379062

Protein	Function_ID	Function_description	E-value
LR134375.1\|VEG94493.1\|2059537_2059813_-\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.576e-21
LR134375.1\|VEG94496.1\|2062224_2062995_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	0.000882596
LR134375.1\|VEG94495.1\|2060908_2062228_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm6	gnl\|CDD\|312974	pfam09659, Cas_Csm6, CRISPR-associated protein (Cas_Csm6). Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.15229e-41
LR134375.1\|VEG94501.1\|2066379_2068935_-\|Predicted-HD-superfamily-hydrolase	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
LR134375.1\|VEG94502.1\|2070125_2071967_-\|Uncharacterized-conserved-protein	gnl\|CDD\|377008	pfam03235, DUF262, Protein of unknown function DUF262.	3.18579e-23
LR134375.1\|VEG94509.1\|2082623_2083667_-\|Protein-involved-in-cell-division	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	3.53145e-23
LR134375.1\|VEG94506.1\|2078697_2079843_-\|Beta-hexosaminidase-A-precursor	gnl\|CDD\|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	5.25056e-25
LR134375.1\|VEG94507.1\|2080254_2081685_-\|Iron-hydrogenase-1	gnl\|CDD\|274171	TIGR02512, Periplasmic_hydrogenase_large_subunit, [FeFe] hydrogenase, group A. This model describes iron-only hydrogenases of anaerobic and microaerophilic bacteria and protozoa. This model is narrower, and covers a longer stretch of sequence, than pfam02906. This family represents a division among families that belong to pfam02906, which also includes proteins such as nuclear prelamin A recognition factor in animals. Note that this family shows some heterogeneity in terms of periplasmic, cytosolic, or hydrogenosome location, NAD or NADP dependence, and overal protein protein length.	6.80641e-179
LR134375.1\|VEG94504.1\|2076054_2076945_-\|RNA-polymerase-sigma-factor,-sigma-70-family	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	8.51516e-14
LR134375.1\|VEG94499.1\|2065160_2065844_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.43444e-71
LR134375.1\|VEG94494.1\|2059814_2060810_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	7.82435e-110
LR134375.1\|VEG94500.1\|2065856_2066369_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	7.39277e-10
LR134375.1\|VEG94497.1\|2062984_2064205_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	4.95403e-18
LR134375.1\|VEG94498.1\|2064152_2065151_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm4	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	3.51218e-28
LR134375.1\|VEG94505.1\|2077279_2078344_-\|Predicted-ATPase-(AAA+-superfamily)	gnl\|CDD\|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.000341189

>LR134375.1|VEG94501.1|2066379_2068935_-|Predicted-HD-superfamily-hydrolase
MGKWDALVKGALLHDIGKVVYRANQGTDAHSKRGAAFIEPYFSDMGLKQSITHCLKYHHGKELSAAQLKNDDYAYIVYEADNIAAAVDRRDLDEGESTATQKFNKELPLQSIFRVFGGNTSNKPLQYYLRGIDASDHFNYPENDKTIRASSDKYKALYDVLVQNFQQQPIDKMSVNELLRIYEDTVSYMPSSTATDQANDISLYMHSKITAAVAHSMVHYFEEQEITDYKEYCYQNSKKFRDMPAFRLISGDISGIQNFIYTIPSKGALKSLRGRSFYLEILMEQIVDELLDALQLTRANLIYNGGGHFYILAPNTTKTSTAIETMEKSINEWFLTVFGTKLYLALGSATAAAAELIQSQRALFRKVSQSVGEAKSKRYSEQHLADLFNPNSTYNTVLHGERECSICHTSTVALSPYGKDTDAEACPICNGLYRLGEQIVDGRDTVFVLARPNISDDSESIPKVEVYVNNLSSDADKGKLYLYVVPESLLQKFESSHEILRIYSKNTAKTGHNVFNRIWLADYVARKDNGQVYEFEELAASSGFGDDKGIKRLGVLRADVDNLGAAFIGGFISEGADKFKYGTLSRYADLSRDLAMFFKVAVNKMAQGDVQGFGTSVTPFTIWANKQVTTRKIHVIYSGGDDVFLVGAWDELLELAIDIREKLAEVTDNKITMSAGLALFSPSYPISQMAAITGLLESVAKDNDGKDSIALFGFETNKNASGEERICRHVYKWDDLINNVIEDKIYTLDQLFVIPGINEKQDAKMKLGKGLIYKLMELLQGVLNDRALGKHINVARILYLLARLEPKKNNPTYESYKNFVTAIHRWIQSEEDCKALLTACNLIVYYMRDTK
>LR134375.1|VEG94500.1|2065856_2066369_-|CRISPR-type-III-A/MTUBE-associated-protein-Csm2
MIQGKFNWDIDIVTKAEETIGRLRYNPKCKKTDEVFDVKYAQVRKILSSVVAIKNKLGVEQRKSKSFDKLPDSIAMEVRFLKTTFLYQAGRDKDYKYPIKSFIEDSQLVEMVECIGTDVKKFDMFCKYVEALVAFYKYRAVSVIADTNDTWNKNKPYNNQNYNQSNGNRR
>LR134375.1|VEG94499.1|2065160_2065844_-|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm3
MENNDNLKSLRGKLLITGTIKLETGMHIGASNDFAPIGSVDTPFIRDVVSQEPIIPGSSIKGKLRTLLAKSHCDDYIMNDIKEDKEEIKRLFGSVNPVKPARLQFYDLFITDETRQLFSNIETDTYMGEIKFENTINRVDGSANPRQIERVPAGTVFTFKVAYNIESEDEVIEDMNILKAGLDLLGIDYLGGHGSRGYGRVNISIDDVKSVGNSTINTQDLLDILRK
>LR134375.1|VEG94498.1|2064152_2065151_-|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm4
MNYYIYPLRFLTPVHFGDTSEGGSLETISLTVGSDALFGACCHEISYDTDLLQSFIDSVKDQHIVLSSLFPYCIDNGEYQLYVPSPIMQIDSKEMPITSFAETKRVATEQKKIKKIEYIRASQLQNYNQYIEADTSQKHMPIFGTRQAMTQVNMRGEKSRPYYVGSYQFMSNTGLYIIAGFIDDDSRELFEAILELLGLSGIGGKRSSGYGKFELADDPIELESEGIYEDDSALYTLLHKKYEKMMCISACVPTCDEVATLKQGSYKLQKRGGFVGTARSTTQVKRNSYYVVKEGSICPKELVGQMLTITGDSLPHAVYRNGMGLWIGVDYE
>LR134375.1|VEG94497.1|2062984_2064205_-|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm5
MLYIVMVWAYGLGWIMSNRIDHAQLLLTVVSPTNIGGPEKLTTKDYMYNYDAGEVYLLNNYEWFRFLARHNKLAEFELYMQDEMVRPNGRTMYDWAKNTVGAAQLTKDALGPVIGSIMKSSIYNKGRKNSLNDITPQIRGANGDVYIPGSSIKGVIDSAIISHMLRNNKAFRSTVQRELKKVLDVYKRKNARNLFKDIFKMVNLVILKHIHVLTNNEGKPFKAILASAFRGLSVSDAMPMGAIQTEVLKKEDSCIDEDGTHAISVHRECILPNQKFSFTVTLDTAMTKEIGITSINQVLDILQEDFDATHKLLASKFKKVSPSIFKALELANAYIGSNTGFVQKTIIMAAFIDDEKTGIDIIKAILDVNFQKAEHDRKDTIMAPRAIKLVKWNGNYYEMGGIHIGR
>LR134375.1|VEG94496.1|2062224_2062995_-|CRISPR-associated-endoribonuclease-Cas6
MADNIEIMAIELGITADPSIKIVQSIGSVLHGVLMELVGTEYAGQLHETGLRPYSQYIYFDKEKGQYIWRLSAVTAEAVERILRPVLNMPEKLFLKQKRGHIYIQDRTVLEETSYEALMAKFWSGEAEYTQAKLRCVTTTSFKVDQQYTIFPEAFRIYRYLLRQWNQFTTFEMMDSDDLLSALESAAFIRDYNLRMGMYGLEGIKIRGFRGEIVMQFKRNLVMQRILSLLTYYSQFTGLGIKTALGMGGVQSEVVQ
>LR134375.1|VEG94495.1|2060908_2062228_-|CRISPR-type-III-A/MTUBE-associated-protein-Csm6
MRILYTPVGDTDPIRGCYDGGMLHIVRHYNPDMAILVLSKDMEQKEAANHRFTKALKHVKADLDIKIIHTGLEDVHRIDVLQPFVDHFYETLSTYPDAEILINLSSGTPQMKLIMSYLSVEHDAVRGIQVDSPQRGSNRSEPAVNDDEDIELVIENNFDDQEDSENRCHEPQMGYIKRNNIKQSLHTLITSYKYKEAISSYHSYKRTFESDVVNDVLPLLEHAQLRLGLNYDDALQKARKVGSTSLSSLFTDKELRKLHEFLMLMEVRLKQGQIEDFVLKTTPFMYELMRYYFTKELNVNWRQVEKKTSKGMRLDMVAFKNQYPKLYESWQENSDTPYLQELQVSFYHMLHMLEDYDTVDSSLLKHLKEIRRIERKIRNKIAHEVVVFTEQDICSAAEIQSLQFFLHQIKDVFFIIARQEKQNKLIYDTINKYVLDQIQ
>LR134375.1|VEG94494.1|2059814_2060810_-|CRISPR-associated-endonuclease-Cas1
MSSLYVTEAGSFIKRDGGHVVVGRNNEVLFEVPLERIEDITVFDSVSITSSLVTDFIERGVPITWLSGYGKYFGTLINTNTIDINKHKKQFDLLDDNAFRVAMSRKIIRAKVRNQLTILRRYARNLEEDINIDAQIANIKSVRSHIGECMRVSELMGYEGLISRLYFEALGKIVPSAFAFTKRTKQPPRDPFNAMLGLGYSMLFNEILAGVINAGLHPFVGIMHSLAKGHPALASDLIEEWRAPIIDSMVLSMVSRNMVDLAEFDNSDKGCYLTAEGRKVFLTAYNKKIRSENQYIDDRKSYRESIYKQCKQFASAIMHEDVDLYTPLEIH
>LR134375.1|VEG94493.1|2059537_2059813_-|CRISPR-associated-endoribonuclease-Cas2
MKKFIVLVIYDVVDNKTRNRLVKCLERYGVRVQKSAFEALLNRKQYDAMMRRASKMINPVEDSLRVYVLDDIINIYTWGIGERKEQDCIVL
>LR134375.1|VEG94492.1|2057088_2058129_-|Uncharacterised-protein
MDVLVSSQLNSVVQSYIGKRIMIVVPSQSVEQGVDAEGSNHLGANSEVESRLATNNQAAAGLPYSYTTGRDWNRHHIPGFVGDNAFGMELMCWSPDRLEDLQEVAAWYVQKYGVHHVLFISLKGEAKILNYDGSRIAGNHKLGPWQAEHIELYGQTLVDDSKNKDGLYQCTSINRDYRLVRAPHCDRSNLEDFGQLFNHLGADHILFVPVIDHKVDGRTMQQYLAFLDVPYDKIHHSFATGENSLYYVLYVRHCRLKLVLDVLQLLFDDSNSKPLLYVTPEGNLYKLRRDMSILQNCGVFSRATYIAMFTKLNKETLQIQLDRDFHYNRPNMFTRMGGAMILGQLK
>LR134375.1|VEG94502.1|2070125_2071967_-|Uncharacterized-conserved-protein
MAEITSLMKDIKGILDNKNQFVIPDFQRSFVWTDKDVDTLFSDFKEDTDNYTDRLDTLPGYLLGNIVLISNENNPTRFDVIDGQQRLTTLTLIFCALNNLFMDIAEETRRNLGANADMWMGHTFSFKEYFRILDNNLQFVDYKILHTQDLDFKETYKSIIKQGALVSDEDNTSANNLEAVYESILQHLRSIYDDEPQKLLYFLQYLTTKVKLIETTAPSIERAFQLFEILNNRGQSLEPLDLLKNYLLKNLTSAPGITQNQIKDFSDSWSQFLKNLKDTGKSKAIETSTFIKHFIIGTKAINVKKKDLFEHFKDNELVANDILQLSSDINSISKVYASINRDPLSNDFLSNDDGMYTLFTLFNTVQIHPLLMPFYNASRVDKVRLVDAAVRYVAAVIFSYTQTNAIEAELPEIIEKILHESDPACRLEVAVTELELRTKPYVDLIRVLLPVKDFGSKNKKQAPKAFQILKFIELYLNQKDSIKTNKKIELEHIMPQAADNADYSFDDEDTRKEYLNHLGNLTLLDKSLNASVKNGNFAEKLDHYKACEFVITRALAEEIDSPVQNQQPLINFQNTYFAVDNPEQITYWDKTQIDERGQKLVEVLEKLLLKQVP
>LR134375.1|VEG94503.1|2074969_2075578_-|Uncharacterised-protein
MMTCNEVPVAVATWLSKGENLDLIYTNPKNHIVCFIPTYEPGGGDSTMCYFVDGRQELVHLPIRTILRELALQEGLRPNYIMTSDGRRSSYTAPKTYGPHLTFGHIKCRRPIGKDVVYGLFNVAIPYQYIVTDGPDPDTSYIHVGDFKPILVYQAPHHVKHKLNEAMLEHCNYVRKMLARIKLSQNPQVVAELFIAWRDLTR
>LR134375.1|VEG94504.1|2076054_2076945_-|RNA-polymerase-sigma-factor,-sigma-70-family
MLYTNEEPLVQRTCIKTASLQSEEISSKGLSSTEVLSKKLSFKDSESEKIPSKESEYKVPEELKLQTLICGHQVLTSLSDKSLVSICQNPNMRIQTVGYQPWSADELRHDAAQIELCRRYRPLILHYTNKTGNREFREDLESYLWAILLESIYSFDLKGSVPFPGFVKAGVRYGYMRYWKRERLRNHREIHIPDRITDDGEVTVGMDIFASGENIADMIMTADEEQRLRARLVWALGRLSQDQQDLLRRVYGDCKSLVSVSEELNCSRQAIQRRHERALRKLRRYLTTDFKKLLVH
>LR134375.1|VEG94505.1|2077279_2078344_-|Predicted-ATPase-(AAA+-superfamily)
MNFVGRAEIIESIQSRIAIDQMSLCVVYGPHRSGKSYVASQLVRRHKALYLAGRMANEAIHVADMNRALEARFVPTDEQDKFEPITSLQEAFEGLFESSVNTPQTVVIDDYPSLVEAVPQFPIHLRDLLEAYQETSHLNIILMANGLEQLDGRIIGDRSLIGSYVSEYFEVKPFSLVDMKSLGLHYAKDDLRTVFAVTGGLPAYVQYFDNGESIETNIINLFFSVSGALFEETQHILHRDMKNITGANAILSGLATLERPYYVELLQASQIKSGTFTSRLNDLMAMGLVGRIQANSRGPAKYADYHFTNSMFHFWYRYVYKYWGDIVRGNGADVYQTYVKPQLKDFVEASCIAM
>LR134375.1|VEG94506.1|2078697_2079843_-|Beta-hexosaminidase-A-precursor
MNLFLRRALCGMALIVAAIGTAGCQHESQAEQEEVRTVSYRAVMQSDKPVPEKVNTWLGAMSQEDKIGQLMMISLHGSTVGQSQKDVIRKYRVSGVMLTNENLNNKNQVKAFTSDIMQTATTASMVTPYIGINRDKVLSTNESFLRLPEPNRWGQLPMERIINLVTRSAIEMRDMGFNLIVGPNANLGVPNVSYTSDPTWAGHMDLAMAERYQINHMWFGYNYFPTVSLGDASFETANDAKAYLNNNDVSVFKRLITQTTANTYMLVISHVQIPAIDNEHLASNSKAIITDWLRHELGYNGVVMTDRVDVGALQANQKIGDFAVNSIVAGSDLVLLDADTGHIDEVHRALIQAVANGTISNDRLNDAVKHILLMKMQTQIQ
>LR134375.1|VEG94507.1|2080254_2081685_-|Iron-hydrogenase-1
MSQYEFIDKRVPIALDNPSIYHDISKCKNCTLCRRACADVMSVLDYYDLDANGDVPVCIHCGQCAAACPFDSMHAKSELEKVKAALADPEKIVVIQTAPAVRVAIGEGFGYEPGTFLEGKMVGALRALGADYVVDTNFGADLTIMEEASELVERLKTGGQIPQFTSCCPAWVRFAEIYFPELIPNLSSTRSCIAMEAAMIKTYFAEKKGINPSNIVSVSVNPCTAKKAETKREEENAAARFYDDESLGMDTDISITTREFIRWIQEENLDFNAIEESQFDDLIGMETGASIIFGNTGGVMEAAMRTAYKLITDKEPPPYALTHLEDVRGMEGVKEATVQLGDDVTLSVAVVHGGKNTRDFLNALKDSDKHYDFIEVMACPGGCIGGGGQPRTKLPQAVKTKEARIGGLYEADANYKWVASYENPEIQALYKDFLGEPLGHKAHELLHTHYTDRSAVLGDRKDVTPETCPTSPKYKG
>LR134375.1|VEG94508.1|2082137_2082512_-|Uncharacterised-protein
MKKTLAAVLAAGALFIGGIGSVDAANWYTVGTDSNGITWSIDNDSVKKDDKKATLDIKAMDYEGYHYIVTEEFNHKKREVKDVKVTLYNPQGYVVKEEQPNKSTRKVEQGTPAYAVYTLIWGDK
>LR134375.1|VEG94509.1|2082623_2083667_-|Protein-involved-in-cell-division
MRRFEYGRIQSLSWDMDILSLIAGIYRANGKEEVLLSQSPAILDSLVELAKVQSTEASNEIEGIVTTSTRLRQLVADKTTPRNRDEQEIMGYRDALNVIHESYDSISLSRNHILQLHKILYNYQFNARGGQLKSVQNYISATYPDGRTEVLFTPLAPYETAEALDKICAEYNRVVGNGEVEPLLAIPIFIHDFLCIHPFNDGNGRMSRLLTTLLLYRSGFMVGKYVSLEAKIARHKDMYYAALRESSDTWYDESSCPIPFICYWLQMLLAAYHDFEDRSSILANSGSAMDQVKAAIDSHLGAFTKQDIREWCPNLSDSSIEGVIRTLVKDGHIQRKGGGRSTYYVKS
>LR134375.1|VEG94510.1|2083858_2084224_-|Uncharacterised-protein
MKKWFACLAVAGLLFSAGVGVSHAESWYALDTDQYGRTGYIDNDSVDKNDARATLRLKIVDPNGDHSIYTMTFNRADKTVQLIDVATYNPQGYMIGSETLANTKVQIQDGSNLDRVYHLIW
>LR134375.1|VEG94511.1|2084573_2084945_-|Uncharacterised-protein
MKKWLAAMFAAGVLFLGGFGQASAADWYYIDADADDAAWFIDNASVYKTDDAATVLVKINNVEGFTYIYTVRIDRKEKTWTELDTTVYSAAGVALLSSKEAQKPTKIEDDTMGAEVMKALWGK

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Crispr_ID: LR134375_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134375_3

2072216-2074585

TypeIII

Consensus_repeat	Method
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	CRISPRCasFinder
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	CRT
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	CRISPRCasFinder
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	PILER-CR

30 spacers

cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6,csm6,cas1,cas2

The CRISPR arrays of LR134375_3

>merge|LR134375|3|2072216-2074585|CRISPRCasFinder,CRT,CRISPRCasFinder,PILER-CR
ATTTCCGTCCCCTATTGGGGATTAATAAATTTGACTAGTTAAAGCATTATATAAATTCATTATTACAACCTTATATAAGTTACCGTCCCCTGTTGGGGATCATTAAATTTAACTAGCATTATGCGTAATTAGTAAAGAATGTGAGAAATGGGAGGAGGTTTCCGTCCCCGAATGGAGATCATTTAATTTAACTCAATCTACCGAAAAGCCTGCTGAAAAGCCTAAAAAAGCAGTTTCCGTCCCCTATTGGGGATCAATAAATTTAACTTTAGACGCTATCAATGGTAGTCAACTATATGCAGTAGTTGAGTTTCCGTCCCCATTAGGGGATTATTTAATTTAACGAAATCATCAAGAATAGTACCTAAGCCGAGTGATTGGCTACTATGTTTTCGTCCCCATCAGGGGATTATTTAATTTAACACGCTAGAAAATTGCAAGAAAAGGAACAATTACCAATCGTAGAGTTTCCGTCCCCATTAGGGGATTATTTAATTTAACTTATTGGAGGTTTAAAATGAAAATCTTTATTAATTATCAACTATTTCCATCCCCATCAGGGGATCAATAAATTTAACGAAAATCGGTATATTTTGCCTTTGGAGATTGGCTTTAGGTTTGTTTCCGTCCCCTATTGGGGAGCAATAAATTTAACGTGAAAAGCTACCTATTCAAGATAGAAAATACGTAGCTACTGTATTTATGTCCCCTGGGGATTATTAAATTTAACCACCTGGTATATTAATCTACAAAACACAATGTTATAGGATTAGTTTTCCGTCCCCTTATGGGGATCATTTAATTTAACCCAACAATAAGGGTTATACATACATCAACTTGCGAGTATTCGTGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACAAGGTGCGTATCGTAGATAGCATTGAGGAATTATGGAGCGGTAGGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACTTACGTAAACAGAATGAAATGCTTATGAAATTGTTACAAGACAAGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACAGCCAATCATGGAAAAGACATACGTTATAGACAGCAAATTAGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACAAGCGGTAGCTTTAATGAAACATGTAAATTACTGTCTTTCGAGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACAGCCAATCATGGAAAAGACATACGTTATAGACAGCAAATTAGTTTCCGTCCCCATCTGGGAATTATTTAATTTAACCGTATGGGTATATTAGCATCAACGGTCTATATGGTTATTGCGAGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACAAACACACAATTAGCGGAGTGAATACATTTGTACTAGATGAAAAGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACCGTTCTCCTCTCTCATGGGTAAAACTACAAAGTTCTGCTTGGGGTTTTCCGTCCCCATCTGGGGATTATTTAATTTAACATGATTTTCTTTGGTTTGATGATGAGTACATCTATGAGAGCTTAGTTTTCCGTCCCCATCTGGGGATTATTTAATTTAACGGCTGTTAAAGCTAAAACTAGCTCAGAAAAGGACTTATTAAAAGTTTTCCGTCCCCATCTGGGGATTATTTAATTTAACAGTACAAAAAGCGGTAGCGAATACATGATAAACCTAAGCCAATTTTCCGTCCCCATCTGGGGATTATTTAATTTAACTTGGAAAGTGGACTGGAACGTAAAAATGGAGGACAAAAATGAATTTTCCGTCCCCATCTGGGGATTATTTAATTTAACATACAGACATTTTAGTAGGCGACCTCGCCAAATTGCTAAACCAGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACACTAATTCTGAAAAAGAGCTTTTAAAAGAACAAAATGCTATGTGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACATAAAACAGTTGAGTTATACAATAGAAATAGCGAATATTATTGGGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACTTTGTACAAGGTGATAATTATTGCTTTGTTACCGCAAAAGGCGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACTAATTCCTGTAAATGTAACTAAGAATGATGAGCAATATGTAAGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACTTTACATCTTTAAAACTACATTTGGTTATGAGCCTGTAATTAAGTTTCCGTCCCCATCTGGGGATTATTTAATTTAACAGAAGAACGCAATTATTTAGAGAACTACGACAAGGACGTATGTGAGTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC

>LR134375|3|3|2072216-2072871|CRISPRCasFinder
ATTTCCGTCCCCTATTGGGGATTAATAAATTTGAC	TAGTTAAAGCATTATATAAATTCATTATTACAACCTTATATAA
GTTACCGTCCCCTGTTGGGGATCATTAAATTTAAC	TAGCATTATGCGTAATTAGTAAAGAATGTGAGAAATGGGAGGAG
GTTTCCGTCCCCGAATGGAGATCATTTAATTTAAC	TCAATCTACCGAAAAGCCTGCTGAAAAGCCTAAAAAAGCA
GTTTCCGTCCCCTATTGGGGATCAATAAATTTAAC	TTTAGACGCTATCAATGGTAGTCAACTATATGCAGTAGTTGA
GTTTCCGTCCCCATTAGGGGATTATTTAATTTAAC	GAAATCATCAAGAATAGTACCTAAGCCGAGTGATTGGCTACTAT
GTTTTCGTCCCCATCAGGGGATTATTTAATTTAAC	ACGCTAGAAAATTGCAAGAAAAGGAACAATTACCAATCGTAGA
GTTTCCGTCCCCATTAGGGGATTATTTAATTTAAC	TTATTGGAGGTTTAAAATGAAAATCTTTATTAATTATCAACT
ATTTCCATCCCCATCAGGGGATCAATAAATTTAAC	GAAAATCGGTATATTTTGCCTTTGGAGATTGGCTTTAGGTTT
GTTTCCGTCCCCTATTGGGGAGCAATAAATTTAACGTGAAAAGCTACCTATTCAAGATAGAAAATACGTAGCTACTGTATTTATGTCCCCTGGGGATTATTAAATTTAACCACCTGGTATATTAATCTACAAAACACAATGTTATAGGATTAGTTTTCCGTCCCCTTATGGGGATCATTTAATTTAAC	CCAACAATAAGGGTTATACATACATCAACTTGCGAGTATTCGT
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAGGTGCGTATCGTAGATAGCATTGAGGAATTATGGAGCGGTAG
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTACGTAAACAGAATGAAATGCTTATGAAATTGTTACAAGACAA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGCCAATCATGGAAAAGACATACGTTATAGACAGCAAATTA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAGCGGTAGCTTTAATGAAACATGTAAATTACTGTCTTTCGA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGCCAATCATGGAAAAGACATACGTTATAGACAGCAAATTA
GTTTCCGTCCCCATCTGGGAATTATTTAATTTAAC	CGTATGGGTATATTAGCATCAACGGTCTATATGGTTATTGCGA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAACACACAATTAGCGGAGTGAATACATTTGTACTAGATGAAAA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	CGTTCTCCTCTCTCATGGGTAAAACTACAAAGTTCTGCTTGGGG
TTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATGATTTTCTTTGGTTTGATGATGAGTACATCTATGAGAGCTTAG
TTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	GGCTGTTAAAGCTAAAACTAGCTCAGAAAAGGACTTATTAAAAG
TTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGTACAAAAAGCGGTAGCGAATACATGATAAACCTAAGCCAA
TTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTGGAAAGTGGACTGGAACGTAAAAATGGAGGACAAAAATGAA
TTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATACAGACATTTTAGTAGGCGACCTCGCCAAATTGCTAAACCA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ACTAATTCTGAAAAAGAGCTTTTAAAAGAACAAAATGCTATGT
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATAAAACAGTTGAGTTATACAATAGAAATAGCGAATATTATTGG
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTTGTACAAGGTGATAATTATTGCTTTGTTACCGCAAAAGGC
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TAATTCCTGTAAATGTAACTAAGAATGATGAGCAATATGTAA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTTACATCTTTAAAACTACATTTGGTTATGAGCCTGTAATTAA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGAAGAACGCAATTATTTAGAGAACTACGACAAGGACGTATGTGA


>LR134375|3|2|2072217-2074585|CRT
TTTCCGTCCCCTATTGGGGATTAATAAATTTGAC	TAGTTAAAGCATTATATAAATTCATTATTACAACCTTATATAAG
TTACCGTCCCCTGTTGGGGATCATTAAATTTAAC	TAGCATTATGCGTAATTAGTAAAGAATGTGAGAAATGGGAGGAGG
TTTCCGTCCCCGAATGGAGATCATTTAATTTAAC	TCAATCTACCGAAAAGCCTGCTGAAAAGCCTAAAAAAGCAG
TTTCCGTCCCCTATTGGGGATCAATAAATTTAAC	TTTAGACGCTATCAATGGTAGTCAACTATATGCAGTAGTTGAG
TTTCCGTCCCCATTAGGGGATTATTTAATTTAAC	GAAATCATCAAGAATAGTACCTAAGCCGAGTGATTGGCTACTATG
TTTTCGTCCCCATCAGGGGATTATTTAATTTAAC	ACGCTAGAAAATTGCAAGAAAAGGAACAATTACCAATCGTAGAG
TTTCCGTCCCCATTAGGGGATTATTTAATTTAAC	TTATTGGAGGTTTAAAATGAAAATCTTTATTAATTATCAACTA
TTTCCATCCCCATCAGGGGATCAATAAATTTAAC	GAAAATCGGTATATTTTGCCTTTGGAGATTGGCTTTAGGTTTG
TTTCCGTCCCCTATTGGGGAGCAATAAATTTAAC	GTGAAAAGCTACCTATTCAAGATAGAAAATACGTAGCTACT
GTATTTATGTCCCCTGGGGATTATTAAATTTAAC	CACCTGGTATATTAATCTACAAAACACAATGTTATAGGATTAGT
TTTCCGTCCCCTTATGGGGATCATTTAATTTAAC	CCAACAATAAGGGTTATACATACATCAACTTGCGAGTATTCGTG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAGGTGCGTATCGTAGATAGCATTGAGGAATTATGGAGCGGTAGG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTACGTAAACAGAATGAAATGCTTATGAAATTGTTACAAGACAAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGCCAATCATGGAAAAGACATACGTTATAGACAGCAAATTAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAGCGGTAGCTTTAATGAAACATGTAAATTACTGTCTTTCGAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGCCAATCATGGAAAAGACATACGTTATAGACAGCAAATTAG
TTTCCGTCCCCATCTGGGAATTATTTAATTTAAC	CGTATGGGTATATTAGCATCAACGGTCTATATGGTTATTGCGAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAACACACAATTAGCGGAGTGAATACATTTGTACTAGATGAAAAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	CGTTCTCCTCTCTCATGGGTAAAACTACAAAGTTCTGCTTGGGGT
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATGATTTTCTTTGGTTTGATGATGAGTACATCTATGAGAGCTTAGT
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	GGCTGTTAAAGCTAAAACTAGCTCAGAAAAGGACTTATTAAAAGT
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGTACAAAAAGCGGTAGCGAATACATGATAAACCTAAGCCAAT
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTGGAAAGTGGACTGGAACGTAAAAATGGAGGACAAAAATGAAT
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATACAGACATTTTAGTAGGCGACCTCGCCAAATTGCTAAACCAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ACTAATTCTGAAAAAGAGCTTTTAAAAGAACAAAATGCTATGTG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATAAAACAGTTGAGTTATACAATAGAAATAGCGAATATTATTGGG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTTGTACAAGGTGATAATTATTGCTTTGTTACCGCAAAAGGCG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TAATTCCTGTAAATGTAACTAAGAATGATGAGCAATATGTAAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTTACATCTTTAAAACTACATTTGGTTATGAGCCTGTAATTAAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGAAGAACGCAATTATTTAGAGAACTACGACAAGGACGTATGTGAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC

>LR134375|3|4|2072989-2074585|CRISPRCasFinder
	TAGTTAAAGCATTATATAAATTCATTATTACAACCTTATATAA
GTTACCGTCCCCTGTTGGGGATCATTAAATTTAAC	TAGCATTATGCGTAATTAGTAAAGAATGTGAGAAATGGGAGGAG
GTTTCCGTCCCCGAATGGAGATCATTTAATTTAAC	TCAATCTACCGAAAAGCCTGCTGAAAAGCCTAAAAAAGCA
GTTTCCGTCCCCTATTGGGGATCAATAAATTTAAC	TTTAGACGCTATCAATGGTAGTCAACTATATGCAGTAGTTGA
GTTTCCGTCCCCATTAGGGGATTATTTAATTTAAC	GAAATCATCAAGAATAGTACCTAAGCCGAGTGATTGGCTACTAT
GTTTTCGTCCCCATCAGGGGATTATTTAATTTAAC	ACGCTAGAAAATTGCAAGAAAAGGAACAATTACCAATCGTAGA
GTTTCCGTCCCCATTAGGGGATTATTTAATTTAAC	TTATTGGAGGTTTAAAATGAAAATCTTTATTAATTATCAACT
ATTTCCATCCCCATCAGGGGATCAATAAATTTAAC	GAAAATCGGTATATTTTGCCTTTGGAGATTGGCTTTAGGTTT
GTTTCCGTCCCCTATTGGGGAGCAATAAATTTAACGTGAAAAGCTACCTATTCAAGATAGAAAATACGTAGCTACTGTATTTATGTCCCCTGGGGATTATTAAATTTAACCACCTGGTATATTAATCTACAAAACACAATGTTATAGGATTAGTTTTCCGTCCCCTTATGGGGATCATTTAATTTAAC	CCAACAATAAGGGTTATACATACATCAACTTGCGAGTATTCGT
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAGGTGCGTATCGTAGATAGCATTGAGGAATTATGGAGCGGTAG
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTACGTAAACAGAATGAAATGCTTATGAAATTGTTACAAGACAA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGCCAATCATGGAAAAGACATACGTTATAGACAGCAAATTA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAGCGGTAGCTTTAATGAAACATGTAAATTACTGTCTTTCGA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGCCAATCATGGAAAAGACATACGTTATAGACAGCAAATTA
GTTTCCGTCCCCATCTGGGAATTATTTAATTTAAC	CGTATGGGTATATTAGCATCAACGGTCTATATGGTTATTGCGA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAACACACAATTAGCGGAGTGAATACATTTGTACTAGATGAAAA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	CGTTCTCCTCTCTCATGGGTAAAACTACAAAGTTCTGCTTGGGG
TTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATGATTTTCTTTGGTTTGATGATGAGTACATCTATGAGAGCTTAG
TTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	GGCTGTTAAAGCTAAAACTAGCTCAGAAAAGGACTTATTAAAAG
TTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGTACAAAAAGCGGTAGCGAATACATGATAAACCTAAGCCAA
TTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTGGAAAGTGGACTGGAACGTAAAAATGGAGGACAAAAATGAA
TTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATACAGACATTTTAGTAGGCGACCTCGCCAAATTGCTAAACCA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ACTAATTCTGAAAAAGAGCTTTTAAAAGAACAAAATGCTATGT
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATAAAACAGTTGAGTTATACAATAGAAATAGCGAATATTATTGG
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTTGTACAAGGTGATAATTATTGCTTTGTTACCGCAAAAGGC
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TAATTCCTGTAAATGTAACTAAGAATGATGAGCAATATGTAA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTTACATCTTTAAAACTACATTTGGTTATGAGCCTGTAATTAA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGAAGAACGCAATTATTTAGAGAACTACGACAAGGACGTATGTGA
GTTTCCGTCCCCATCTGGGGATTATTTAATTTAAC

>LR134375|3|2|2073068-2074585|PILER-CR
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAGGTGCGTATCGTAGATAGCATTGAGGAATTATGGAGCGGTAGG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTACGTAAACAGAATGAAATGCTTATGAAATTGTTACAAGACAAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGCCAATCATGGAAAAGACATACGTTATAGACAGCAAATTAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAGCGGTAGCTTTAATGAAACATGTAAATTACTGTCTTTCGAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGCCAATCATGGAAAAGACATACGTTATAGACAGCAAATTAG
TTTCCGTCCCCATCTGGGAATTATTTAATTTAAC	CGTATGGGTATATTAGCATCAACGGTCTATATGGTTATTGCGAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AAACACACAATTAGCGGAGTGAATACATTTGTACTAGATGAAAAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	CGTTCTCCTCTCTCATGGGTAAAACTACAAAGTTCTGCTTGGGGT
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATGATTTTCTTTGGTTTGATGATGAGTACATCTATGAGAGCTTAGT
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	GGCTGTTAAAGCTAAAACTAGCTCAGAAAAGGACTTATTAAAAGT
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGTACAAAAAGCGGTAGCGAATACATGATAAACCTAAGCCAAT
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTGGAAAGTGGACTGGAACGTAAAAATGGAGGACAAAAATGAAT
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATACAGACATTTTAGTAGGCGACCTCGCCAAATTGCTAAACCAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ACTAATTCTGAAAAAGAGCTTTTAAAAGAACAAAATGCTATGTG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	ATAAAACAGTTGAGTTATACAATAGAAATAGCGAATATTATTGGG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTTGTACAAGGTGATAATTATTGCTTTGTTACCGCAAAAGGCG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TAATTCCTGTAAATGTAACTAAGAATGATGAGCAATATGTAAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	TTTACATCTTTAAAACTACATTTGGTTATGAGCCTGTAATTAAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC	AGAAGAACGCAATTATTTAGAGAACTACGACAAGGACGTATGTGAG
TTTCCGTCCCCATCTGGGGATTATTTAATTTAAC

Protein	Signature genes	Signature genes Name	Protein_function
LR134375.1\|VEG94511.1\|2084573_2084945_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94493.1\|2059537_2059813_-\|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
LR134375.1\|VEG94496.1\|2062224_2062995_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam10040_cas6_CAS-III:CAS-IV	gnl\|CDD\|227838
LR134375.1\|VEG94495.1\|2060908_2062228_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm6	csm6	pfam09659_csm6_CAS-III-A	gnl\|CDD\|312974
LR134375.1\|VEG94501.1\|2066379_2068935_-\|Predicted-HD-superfamily-hydrolase	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
LR134375.1\|VEG94512.1\|2085021_2087493_-\|DNA-gyrase-subunit-A	unknown	unknown	gnl\|CDD\|235502
LR134375.1\|VEG94503.1\|2074969_2075578_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94509.1\|2082623_2083667_-\|Protein-involved-in-cell-division	unknown	unknown	gnl\|CDD\|225718
LR134375.1\|VEG94506.1\|2078697_2079843_-\|Beta-hexosaminidase-A-precursor	unknown	unknown	gnl\|CDD\|224389
LR134375.1\|VEG94507.1\|2080254_2081685_-\|Iron-hydrogenase-1	unknown	unknown	gnl\|CDD\|274171
LR134375.1\|VEG94499.1\|2065160_2065844_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
LR134375.1\|VEG94502.1\|2070125_2071967_-\|Uncharacterized-conserved-protein	unknown	unknown	gnl\|CDD\|377008
LR134375.1\|VEG94494.1\|2059814_2060810_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
LR134375.1\|VEG94500.1\|2065856_2066369_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm2	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|367635
LR134375.1\|VEG94497.1\|2062984_2064205_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
LR134375.1\|VEG94508.1\|2082137_2082512_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94504.1\|2076054_2076945_-\|RNA-polymerase-sigma-factor,-sigma-70-family	unknown	unknown	gnl\|CDD\|274357
LR134375.1\|VEG94510.1\|2083858_2084224_-\|Uncharacterised-protein	unknown	unknown	unknown
LR134375.1\|VEG94498.1\|2064152_2065151_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm4	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|380071
LR134375.1\|VEG94505.1\|2077279_2078344_-\|Predicted-ATPase-(AAA+-superfamily)	unknown	unknown	gnl\|CDD\|379062

Protein	Function_ID	Function_description	E-value
LR134375.1\|VEG94512.1\|2085021_2087493_-\|DNA-gyrase-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
LR134375.1\|VEG94493.1\|2059537_2059813_-\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	9.576e-21
LR134375.1\|VEG94496.1\|2062224_2062995_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|227838	COG5551, COG5551, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	0.000882596
LR134375.1\|VEG94495.1\|2060908_2062228_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm6	gnl\|CDD\|312974	pfam09659, Cas_Csm6, CRISPR-associated protein (Cas_Csm6). Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	1.15229e-41
LR134375.1\|VEG94501.1\|2066379_2068935_-\|Predicted-HD-superfamily-hydrolase	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
LR134375.1\|VEG94502.1\|2070125_2071967_-\|Uncharacterized-conserved-protein	gnl\|CDD\|377008	pfam03235, DUF262, Protein of unknown function DUF262.	3.18579e-23
LR134375.1\|VEG94509.1\|2082623_2083667_-\|Protein-involved-in-cell-division	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	3.53145e-23
LR134375.1\|VEG94506.1\|2078697_2079843_-\|Beta-hexosaminidase-A-precursor	gnl\|CDD\|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	5.25056e-25
LR134375.1\|VEG94507.1\|2080254_2081685_-\|Iron-hydrogenase-1	gnl\|CDD\|274171	TIGR02512, Periplasmic_hydrogenase_large_subunit, [FeFe] hydrogenase, group A. This model describes iron-only hydrogenases of anaerobic and microaerophilic bacteria and protozoa. This model is narrower, and covers a longer stretch of sequence, than pfam02906. This family represents a division among families that belong to pfam02906, which also includes proteins such as nuclear prelamin A recognition factor in animals. Note that this family shows some heterogeneity in terms of periplasmic, cytosolic, or hydrogenosome location, NAD or NADP dependence, and overal protein protein length.	6.80641e-179
LR134375.1\|VEG94504.1\|2076054_2076945_-\|RNA-polymerase-sigma-factor,-sigma-70-family	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	8.51516e-14
LR134375.1\|VEG94499.1\|2065160_2065844_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.43444e-71
LR134375.1\|VEG94494.1\|2059814_2060810_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	7.82435e-110
LR134375.1\|VEG94500.1\|2065856_2066369_-\|CRISPR-type-III-A/MTUBE-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	7.39277e-10
LR134375.1\|VEG94497.1\|2062984_2064205_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	4.95403e-18
LR134375.1\|VEG94498.1\|2064152_2065151_-\|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm4	gnl\|CDD\|380071	pfam17953, Csm4_C, CRISPR Csm4 C-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. The interference complex of the type III-A CRISPR-Cas system is composed of five Cas proteins (Csm1-Csm5) and a crRNA, and targets invading DNA. This entry represents the C-terminal domain found in Csm4. Csm4 structurally resembles Cmr3, a component of the type III-B CRISPR-Cas interference complex. Studies indicate that Csm3-Csm4 complex binds single-stranded RNA in a non-sequence-specific manner. Structural analysis show, Csm3 and Csm4 have one and two ferredoxin-like folds (also known as an RRM-like fold), respectively. The long beta-hairpin inserted into the C-terminal ferredoxin-like fold of Csm4, is well-conserved in the Cmr3 structure. The corresponding beta-hairpin of Cmr3 binds the D1 domain of Cmr2, as observed in the Cmr2-Cmr3 complex structure. Furthermore, it is suggested that the hairpin of Csm4 is responsible for the interaction with Csm1 (ortholog of Cmr2).	3.51218e-28
LR134375.1\|VEG94505.1\|2077279_2078344_-\|Predicted-ATPase-(AAA+-superfamily)	gnl\|CDD\|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.000341189

>LR134375.1|VEG94502.1|2070125_2071967_-|Uncharacterized-conserved-protein
MAEITSLMKDIKGILDNKNQFVIPDFQRSFVWTDKDVDTLFSDFKEDTDNYTDRLDTLPGYLLGNIVLISNENNPTRFDVIDGQQRLTTLTLIFCALNNLFMDIAEETRRNLGANADMWMGHTFSFKEYFRILDNNLQFVDYKILHTQDLDFKETYKSIIKQGALVSDEDNTSANNLEAVYESILQHLRSIYDDEPQKLLYFLQYLTTKVKLIETTAPSIERAFQLFEILNNRGQSLEPLDLLKNYLLKNLTSAPGITQNQIKDFSDSWSQFLKNLKDTGKSKAIETSTFIKHFIIGTKAINVKKKDLFEHFKDNELVANDILQLSSDINSISKVYASINRDPLSNDFLSNDDGMYTLFTLFNTVQIHPLLMPFYNASRVDKVRLVDAAVRYVAAVIFSYTQTNAIEAELPEIIEKILHESDPACRLEVAVTELELRTKPYVDLIRVLLPVKDFGSKNKKQAPKAFQILKFIELYLNQKDSIKTNKKIELEHIMPQAADNADYSFDDEDTRKEYLNHLGNLTLLDKSLNASVKNGNFAEKLDHYKACEFVITRALAEEIDSPVQNQQPLINFQNTYFAVDNPEQITYWDKTQIDERGQKLVEVLEKLLLKQVP
>LR134375.1|VEG94501.1|2066379_2068935_-|Predicted-HD-superfamily-hydrolase
MGKWDALVKGALLHDIGKVVYRANQGTDAHSKRGAAFIEPYFSDMGLKQSITHCLKYHHGKELSAAQLKNDDYAYIVYEADNIAAAVDRRDLDEGESTATQKFNKELPLQSIFRVFGGNTSNKPLQYYLRGIDASDHFNYPENDKTIRASSDKYKALYDVLVQNFQQQPIDKMSVNELLRIYEDTVSYMPSSTATDQANDISLYMHSKITAAVAHSMVHYFEEQEITDYKEYCYQNSKKFRDMPAFRLISGDISGIQNFIYTIPSKGALKSLRGRSFYLEILMEQIVDELLDALQLTRANLIYNGGGHFYILAPNTTKTSTAIETMEKSINEWFLTVFGTKLYLALGSATAAAAELIQSQRALFRKVSQSVGEAKSKRYSEQHLADLFNPNSTYNTVLHGERECSICHTSTVALSPYGKDTDAEACPICNGLYRLGEQIVDGRDTVFVLARPNISDDSESIPKVEVYVNNLSSDADKGKLYLYVVPESLLQKFESSHEILRIYSKNTAKTGHNVFNRIWLADYVARKDNGQVYEFEELAASSGFGDDKGIKRLGVLRADVDNLGAAFIGGFISEGADKFKYGTLSRYADLSRDLAMFFKVAVNKMAQGDVQGFGTSVTPFTIWANKQVTTRKIHVIYSGGDDVFLVGAWDELLELAIDIREKLAEVTDNKITMSAGLALFSPSYPISQMAAITGLLESVAKDNDGKDSIALFGFETNKNASGEERICRHVYKWDDLINNVIEDKIYTLDQLFVIPGINEKQDAKMKLGKGLIYKLMELLQGVLNDRALGKHINVARILYLLARLEPKKNNPTYESYKNFVTAIHRWIQSEEDCKALLTACNLIVYYMRDTK
>LR134375.1|VEG94500.1|2065856_2066369_-|CRISPR-type-III-A/MTUBE-associated-protein-Csm2
MIQGKFNWDIDIVTKAEETIGRLRYNPKCKKTDEVFDVKYAQVRKILSSVVAIKNKLGVEQRKSKSFDKLPDSIAMEVRFLKTTFLYQAGRDKDYKYPIKSFIEDSQLVEMVECIGTDVKKFDMFCKYVEALVAFYKYRAVSVIADTNDTWNKNKPYNNQNYNQSNGNRR
>LR134375.1|VEG94499.1|2065160_2065844_-|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm3
MENNDNLKSLRGKLLITGTIKLETGMHIGASNDFAPIGSVDTPFIRDVVSQEPIIPGSSIKGKLRTLLAKSHCDDYIMNDIKEDKEEIKRLFGSVNPVKPARLQFYDLFITDETRQLFSNIETDTYMGEIKFENTINRVDGSANPRQIERVPAGTVFTFKVAYNIESEDEVIEDMNILKAGLDLLGIDYLGGHGSRGYGRVNISIDDVKSVGNSTINTQDLLDILRK
>LR134375.1|VEG94498.1|2064152_2065151_-|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm4
MNYYIYPLRFLTPVHFGDTSEGGSLETISLTVGSDALFGACCHEISYDTDLLQSFIDSVKDQHIVLSSLFPYCIDNGEYQLYVPSPIMQIDSKEMPITSFAETKRVATEQKKIKKIEYIRASQLQNYNQYIEADTSQKHMPIFGTRQAMTQVNMRGEKSRPYYVGSYQFMSNTGLYIIAGFIDDDSRELFEAILELLGLSGIGGKRSSGYGKFELADDPIELESEGIYEDDSALYTLLHKKYEKMMCISACVPTCDEVATLKQGSYKLQKRGGFVGTARSTTQVKRNSYYVVKEGSICPKELVGQMLTITGDSLPHAVYRNGMGLWIGVDYE
>LR134375.1|VEG94497.1|2062984_2064205_-|CRISPR-type-III-A/MTUBE-associated-RAMP-protein-Csm5
MLYIVMVWAYGLGWIMSNRIDHAQLLLTVVSPTNIGGPEKLTTKDYMYNYDAGEVYLLNNYEWFRFLARHNKLAEFELYMQDEMVRPNGRTMYDWAKNTVGAAQLTKDALGPVIGSIMKSSIYNKGRKNSLNDITPQIRGANGDVYIPGSSIKGVIDSAIISHMLRNNKAFRSTVQRELKKVLDVYKRKNARNLFKDIFKMVNLVILKHIHVLTNNEGKPFKAILASAFRGLSVSDAMPMGAIQTEVLKKEDSCIDEDGTHAISVHRECILPNQKFSFTVTLDTAMTKEIGITSINQVLDILQEDFDATHKLLASKFKKVSPSIFKALELANAYIGSNTGFVQKTIIMAAFIDDEKTGIDIIKAILDVNFQKAEHDRKDTIMAPRAIKLVKWNGNYYEMGGIHIGR
>LR134375.1|VEG94496.1|2062224_2062995_-|CRISPR-associated-endoribonuclease-Cas6
MADNIEIMAIELGITADPSIKIVQSIGSVLHGVLMELVGTEYAGQLHETGLRPYSQYIYFDKEKGQYIWRLSAVTAEAVERILRPVLNMPEKLFLKQKRGHIYIQDRTVLEETSYEALMAKFWSGEAEYTQAKLRCVTTTSFKVDQQYTIFPEAFRIYRYLLRQWNQFTTFEMMDSDDLLSALESAAFIRDYNLRMGMYGLEGIKIRGFRGEIVMQFKRNLVMQRILSLLTYYSQFTGLGIKTALGMGGVQSEVVQ
>LR134375.1|VEG94495.1|2060908_2062228_-|CRISPR-type-III-A/MTUBE-associated-protein-Csm6
MRILYTPVGDTDPIRGCYDGGMLHIVRHYNPDMAILVLSKDMEQKEAANHRFTKALKHVKADLDIKIIHTGLEDVHRIDVLQPFVDHFYETLSTYPDAEILINLSSGTPQMKLIMSYLSVEHDAVRGIQVDSPQRGSNRSEPAVNDDEDIELVIENNFDDQEDSENRCHEPQMGYIKRNNIKQSLHTLITSYKYKEAISSYHSYKRTFESDVVNDVLPLLEHAQLRLGLNYDDALQKARKVGSTSLSSLFTDKELRKLHEFLMLMEVRLKQGQIEDFVLKTTPFMYELMRYYFTKELNVNWRQVEKKTSKGMRLDMVAFKNQYPKLYESWQENSDTPYLQELQVSFYHMLHMLEDYDTVDSSLLKHLKEIRRIERKIRNKIAHEVVVFTEQDICSAAEIQSLQFFLHQIKDVFFIIARQEKQNKLIYDTINKYVLDQIQ
>LR134375.1|VEG94494.1|2059814_2060810_-|CRISPR-associated-endonuclease-Cas1
MSSLYVTEAGSFIKRDGGHVVVGRNNEVLFEVPLERIEDITVFDSVSITSSLVTDFIERGVPITWLSGYGKYFGTLINTNTIDINKHKKQFDLLDDNAFRVAMSRKIIRAKVRNQLTILRRYARNLEEDINIDAQIANIKSVRSHIGECMRVSELMGYEGLISRLYFEALGKIVPSAFAFTKRTKQPPRDPFNAMLGLGYSMLFNEILAGVINAGLHPFVGIMHSLAKGHPALASDLIEEWRAPIIDSMVLSMVSRNMVDLAEFDNSDKGCYLTAEGRKVFLTAYNKKIRSENQYIDDRKSYRESIYKQCKQFASAIMHEDVDLYTPLEIH
>LR134375.1|VEG94493.1|2059537_2059813_-|CRISPR-associated-endoribonuclease-Cas2
MKKFIVLVIYDVVDNKTRNRLVKCLERYGVRVQKSAFEALLNRKQYDAMMRRASKMINPVEDSLRVYVLDDIINIYTWGIGERKEQDCIVL
>LR134375.1|VEG94503.1|2074969_2075578_-|Uncharacterised-protein
MMTCNEVPVAVATWLSKGENLDLIYTNPKNHIVCFIPTYEPGGGDSTMCYFVDGRQELVHLPIRTILRELALQEGLRPNYIMTSDGRRSSYTAPKTYGPHLTFGHIKCRRPIGKDVVYGLFNVAIPYQYIVTDGPDPDTSYIHVGDFKPILVYQAPHHVKHKLNEAMLEHCNYVRKMLARIKLSQNPQVVAELFIAWRDLTR
>LR134375.1|VEG94504.1|2076054_2076945_-|RNA-polymerase-sigma-factor,-sigma-70-family
MLYTNEEPLVQRTCIKTASLQSEEISSKGLSSTEVLSKKLSFKDSESEKIPSKESEYKVPEELKLQTLICGHQVLTSLSDKSLVSICQNPNMRIQTVGYQPWSADELRHDAAQIELCRRYRPLILHYTNKTGNREFREDLESYLWAILLESIYSFDLKGSVPFPGFVKAGVRYGYMRYWKRERLRNHREIHIPDRITDDGEVTVGMDIFASGENIADMIMTADEEQRLRARLVWALGRLSQDQQDLLRRVYGDCKSLVSVSEELNCSRQAIQRRHERALRKLRRYLTTDFKKLLVH
>LR134375.1|VEG94505.1|2077279_2078344_-|Predicted-ATPase-(AAA+-superfamily)
MNFVGRAEIIESIQSRIAIDQMSLCVVYGPHRSGKSYVASQLVRRHKALYLAGRMANEAIHVADMNRALEARFVPTDEQDKFEPITSLQEAFEGLFESSVNTPQTVVIDDYPSLVEAVPQFPIHLRDLLEAYQETSHLNIILMANGLEQLDGRIIGDRSLIGSYVSEYFEVKPFSLVDMKSLGLHYAKDDLRTVFAVTGGLPAYVQYFDNGESIETNIINLFFSVSGALFEETQHILHRDMKNITGANAILSGLATLERPYYVELLQASQIKSGTFTSRLNDLMAMGLVGRIQANSRGPAKYADYHFTNSMFHFWYRYVYKYWGDIVRGNGADVYQTYVKPQLKDFVEASCIAM
>LR134375.1|VEG94506.1|2078697_2079843_-|Beta-hexosaminidase-A-precursor
MNLFLRRALCGMALIVAAIGTAGCQHESQAEQEEVRTVSYRAVMQSDKPVPEKVNTWLGAMSQEDKIGQLMMISLHGSTVGQSQKDVIRKYRVSGVMLTNENLNNKNQVKAFTSDIMQTATTASMVTPYIGINRDKVLSTNESFLRLPEPNRWGQLPMERIINLVTRSAIEMRDMGFNLIVGPNANLGVPNVSYTSDPTWAGHMDLAMAERYQINHMWFGYNYFPTVSLGDASFETANDAKAYLNNNDVSVFKRLITQTTANTYMLVISHVQIPAIDNEHLASNSKAIITDWLRHELGYNGVVMTDRVDVGALQANQKIGDFAVNSIVAGSDLVLLDADTGHIDEVHRALIQAVANGTISNDRLNDAVKHILLMKMQTQIQ
>LR134375.1|VEG94507.1|2080254_2081685_-|Iron-hydrogenase-1
MSQYEFIDKRVPIALDNPSIYHDISKCKNCTLCRRACADVMSVLDYYDLDANGDVPVCIHCGQCAAACPFDSMHAKSELEKVKAALADPEKIVVIQTAPAVRVAIGEGFGYEPGTFLEGKMVGALRALGADYVVDTNFGADLTIMEEASELVERLKTGGQIPQFTSCCPAWVRFAEIYFPELIPNLSSTRSCIAMEAAMIKTYFAEKKGINPSNIVSVSVNPCTAKKAETKREEENAAARFYDDESLGMDTDISITTREFIRWIQEENLDFNAIEESQFDDLIGMETGASIIFGNTGGVMEAAMRTAYKLITDKEPPPYALTHLEDVRGMEGVKEATVQLGDDVTLSVAVVHGGKNTRDFLNALKDSDKHYDFIEVMACPGGCIGGGGQPRTKLPQAVKTKEARIGGLYEADANYKWVASYENPEIQALYKDFLGEPLGHKAHELLHTHYTDRSAVLGDRKDVTPETCPTSPKYKG
>LR134375.1|VEG94508.1|2082137_2082512_-|Uncharacterised-protein
MKKTLAAVLAAGALFIGGIGSVDAANWYTVGTDSNGITWSIDNDSVKKDDKKATLDIKAMDYEGYHYIVTEEFNHKKREVKDVKVTLYNPQGYVVKEEQPNKSTRKVEQGTPAYAVYTLIWGDK
>LR134375.1|VEG94509.1|2082623_2083667_-|Protein-involved-in-cell-division
MRRFEYGRIQSLSWDMDILSLIAGIYRANGKEEVLLSQSPAILDSLVELAKVQSTEASNEIEGIVTTSTRLRQLVADKTTPRNRDEQEIMGYRDALNVIHESYDSISLSRNHILQLHKILYNYQFNARGGQLKSVQNYISATYPDGRTEVLFTPLAPYETAEALDKICAEYNRVVGNGEVEPLLAIPIFIHDFLCIHPFNDGNGRMSRLLTTLLLYRSGFMVGKYVSLEAKIARHKDMYYAALRESSDTWYDESSCPIPFICYWLQMLLAAYHDFEDRSSILANSGSAMDQVKAAIDSHLGAFTKQDIREWCPNLSDSSIEGVIRTLVKDGHIQRKGGGRSTYYVKS
>LR134375.1|VEG94510.1|2083858_2084224_-|Uncharacterised-protein
MKKWFACLAVAGLLFSAGVGVSHAESWYALDTDQYGRTGYIDNDSVDKNDARATLRLKIVDPNGDHSIYTMTFNRADKTVQLIDVATYNPQGYMIGSETLANTKVQIQDGSNLDRVYHLIW
>LR134375.1|VEG94511.1|2084573_2084945_-|Uncharacterised-protein
MKKWLAAMFAAGVLFLGGFGQASAADWYYIDADADDAAWFIDNASVYKTDDAATVLVKINNVEGFTYIYTVRIDRKEKTWTELDTTVYSAAGVALLSSKEAQKPTKIEDDTMGAEVMKALWGK
>LR134375.1|VEG94512.1|2085021_2087493_-|DNA-gyrase-subunit-A
MADQQWSHGNIHPVQIDKEMKNAYIDYAMSVIVMRALPDVRDGLKPVHRRILYAMHETGMTPNKPYKKSARIVGDVLGKYHPHGDSSVYDATVRLAQDFNTRYLLVDGHGNFGSIDGDSAAAMRYTEVRMAKITQEMLADIDKETVDFMPNYDESLQEPTVLPAKIPNLLINGSSGIAVGMATNIPPHNLNEVCNGLTMLIDNPDVTVEELMTQIKGPDFPTGALILGREGIKKAYSTGRGSVKMRARATIEEMAKGKHKIVVTEIPYQVNKARVIETIANLSRDKVIDGITALRDESDRQGMRIVIELRADVQPDIVLNKLYKHTQLQESFGVIMLALVDGHPRVLNLKEVLGYYLDHRLDVIVRRTQFELNKAEARAHILEGLLIALDHIDEVIATIRSSQTDEIARNALMQKFGLSEKQAVAILDMRLRRLTGLEREKIEEEYKELLALIEDLKAILASEARQRQIIKEELEDMKKKYGDPRRSEITIDTSDLDVEDLIADEEMVITLTKQGYIKRMNANVYRNQHKGGAGVIGMKTKEDDYVTQIMHVRTHNTLLFFTSTGRTYRLKAYEVPEAGSRNSRGTAMVNVLPLAVGESVTTMIDLERIHEDVNLFMVTEFGVVKRTAIEEYRNIRRSGLNAINLDEGDRLISVSVTTGNQDILIGTKLGIAIRFSESDVRLMKRAAHGVRGIKLNTGDVVVGAGVLNADESEAQVFTISEEGFGKRNDAEAYTLQKRGGKGSKNFKITNKTGDVVAVEVVHNDDEVMLISEQGKIIRFNMNDIAVKKGKAISGVKTQNLDEGDKVASIAVIPGAEIEDEEAE

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

389955 : 395922

Synechococcus_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEG92942.1\|389955_390447_+	N5-carboxyaminoimidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.5e-31	47.1
VEG92943.1\|390553_391282_+	Phosphoribosylaminoimidazole-succinocarboxamide synthase	G8EYA2	Synechococcus_phage	2.2e-47	43.5
VEG92944.1\|391291_392710_+	Amidophosphoribosyltransferase precursor	A0A1B1ISH6	uncultured_Mediterranean_phage	3.7e-51	30.7
VEG92945.1\|392696_393758_+	Phosphoribosylformylglycinamidine cyclo-ligase	A0A1D8KLC2	Synechococcus_phage	5.4e-63	41.0
VEG92946.1\|393750_394368_+	Phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	9.6e-20	32.1
VEG92947.1\|394392_395922_+	Bifunctional purine biosynthesis protein PurH	Q58MG4	Prochlorococcus_phage	6.9e-75	52.0

DBSCAN-SWA_2

603094 : 671528

Clostridium_phage(27.59%)

tail,tRNA,protease,terminase,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEG93133.1\|603094_605509_+	Predicted P-loop ATPase and inactivated derivatives	A0A1S7FZ15	Listeria_phage	9.7e-209	47.5
VEG93134.1\|606195_607563_+	DNA methylase	D2J050	Enterococcus_phage	2.7e-147	56.7
VEG93135.1\|607567_608065_+	Protein of unknwon function (DUF3310)	A0A1B1IWM3	uncultured_Mediterranean_phage	4.3e-18	67.2
VEG93136.1\|608057_608486_+	Protein of uncharacterised function (DUF1492)	NA	NA	NA	NA
VEG93137.1\|609133_609577_+	Terminase small subunit	A7J290	Streptococcus_phage	1.4e-12	36.2
VEG93138.1\|609566_610805_+\|terminase	phage terminase, large subunit, PBSX family	A0A0S0KEN9	Bacillus_phage	5.8e-125	54.0
VEG93139.1\|610801_612217_+\|portal	phage portal protein, SPP1 family	S5MNW1	Brevibacillus_phage	4.1e-90	39.5
VEG93140.1\|612206_613229_+	NAD+--asparagine ADP-ribosyltransferase	X5JAI9	Clostridium_phage	1.3e-56	35.6
VEG93141.1\|613351_613966_+	Phage minor structural protein GP20	I1TLE1	Bacillus_phage	6.9e-18	42.2
VEG93142.1\|613958_614843_+	Uncharacterised protein	A0A059NT82	Lactococcus_phage	1.0e-46	38.2
VEG93143.1\|614855_615224_+	Uncharacterised protein	NA	NA	NA	NA
VEG93144.1\|615199_615571_+	Uncharacterised protein	NA	NA	NA	NA
VEG93145.1\|615572_616091_+	Uncharacterised protein	NA	NA	NA	NA
VEG93146.1\|616077_616515_+	Uncharacterised protein	NA	NA	NA	NA
VEG93147.1\|616504_616696_+	Uncharacterised protein	NA	NA	NA	NA
VEG93148.1\|616702_618058_+\|tail	Phage tail sheath protein	A0A0A8WIF0	Clostridium_phage	3.4e-110	49.0
VEG93149.1\|618069_618564_+	Phage-like element PBSX protein xkdM	A0A0A8WJ62	Clostridium_phage	7.9e-33	44.0
VEG93150.1\|618597_619026_+	Phage XkdN-like protein	X5JAB6	Clostridium_phage	3.3e-19	40.3
VEG93151.1\|619199_621215_+\|tail	Phage-related minor tail protein	X5JAB7	Clostridium_phage	4.1e-59	29.3
VEG93152.1\|621215_621899_+	Uncharacterised protein	X5J9Z8	Clostridium_phage	1.3e-25	35.1
VEG93153.1\|621889_623446_+	Uncharacterised protein	H7BVH4	unidentified_phage	1.9e-56	39.8
VEG93154.1\|623445_623859_+	Protein of uncharacterised function (DUF2577)	NA	NA	NA	NA
VEG93155.1\|623858_624290_+	Protein of uncharacterised function (DUF2634)	A0A0A8WFW6	Clostridium_phage	3.1e-25	47.4
VEG93156.1\|624294_625362_+	Uncharacterized homolog of phage Mu protein gp47	X5JAB8	Clostridium_phage	3.5e-70	42.3
VEG93157.1\|625358_625991_+	Uncharacterized protein conserved in bacteria (DUF2313)	NA	NA	NA	NA
VEG93158.1\|626000_626906_+	Uncharacterised protein	A0A0C5AEQ0	Bacteriophage	9.2e-11	30.7
VEG93159.1\|627382_628228_-	site-specific tyrosine recombinase XerD	A0A0E3Y5J2	Fusobacterium_phage	2.3e-32	33.5
VEG93160.1\|628254_628647_+	Uncharacterised protein	NA	NA	NA	NA
VEG93161.1\|628648_628813_+	Uncharacterised protein	NA	NA	NA	NA
VEG93162.1\|628784_629123_+	Uncharacterised protein	NA	NA	NA	NA
VEG93163.1\|629122_630439_+	Collagen triple helix repeat (20 copies)	NA	NA	NA	NA
VEG93164.1\|630442_630772_+	Uncharacterised protein	NA	NA	NA	NA
VEG93165.1\|630737_631079_+	Uncharacterised protein	NA	NA	NA	NA
VEG93166.1\|631075_631594_+	N-acetylmuramoyl-L-alanine amidase LytC precursor	A0A2I7S6C9	Vibrio_phage	1.9e-13	35.8
VEG93167.1\|631593_632079_+	Uncharacterised protein	NA	NA	NA	NA
VEG93168.1\|632678_632966_+	Transposase and inactivated derivatives	NA	NA	NA	NA
VEG93169.1\|633228_634170_+	Probable deferrochelatase/peroxidase YfeX	NA	NA	NA	NA
VEG93170.1\|634349_635849_+	Threonine synthase	NA	NA	NA	NA
VEG93171.1\|635993_636881_+	Predicted permeases	NA	NA	NA	NA
VEG93172.1\|637138_637606_+	Large-conductance mechanosensitive channel	NA	NA	NA	NA
VEG93173.1\|637777_638827_+	Glyoxylate/hydroxypyruvate reductase B	M1NSB9	Streptococcus_phage	4.3e-20	27.6
VEG93174.1\|638909_640598_+\|tRNA	Glutamine--tRNA ligase	A0A222YZ70	Escherichia_phage	1.2e-173	57.6
VEG93175.1\|640725_641361_+	Uncharacterised protein	NA	NA	NA	NA
VEG93176.1\|641462_642050_+	Protein of uncharacterised function (DUF3793)	NA	NA	NA	NA
VEG93177.1\|642060_642480_+	Flavodoxin	NA	NA	NA	NA
VEG93178.1\|643025_643658_+	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VEG93179.1\|643667_644879_+	Diaminopropionate ammonia-lyase	NA	NA	NA	NA
VEG93180.1\|644891_646202_+	Acetylornithine deacetylase	NA	NA	NA	NA
VEG93181.1\|646357_647551_+	aspartate/ornithine carbamoyltransferase family protein	NA	NA	NA	NA
VEG93182.1\|647620_648556_+	Carbamate kinase 1	NA	NA	NA	NA
VEG93183.1\|648608_649937_+	putative chlorohydrolase/aminohydrolase	NA	NA	NA	NA
VEG93184.1\|649965_651657_+	putative selenate reductase subunit YgfK	NA	NA	NA	NA
VEG93185.1\|651653_653003_+	D-hydantoinase	NA	NA	NA	NA
VEG93186.1\|653020_655570_+	Aldehyde oxidoreductase	NA	NA	NA	NA
VEG93187.1\|655717_657103_+	Putative purine permease ygfU	Q9KX94	Enterobacteria_phage	5.0e-32	31.7
VEG93188.1\|657307_658498_+	2,3-diketo-5-methylthiopentyl-1-phosphate enolase	NA	NA	NA	NA
VEG93189.1\|658604_659411_+	ribonuclease Z	NA	NA	NA	NA
VEG93190.1\|659414_659894_+	Ribosomal RNA large subunit methyltransferase H	NA	NA	NA	NA
VEG93191.1\|660096_660552_+	putative manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
VEG93192.1\|660715_662020_+	Trigger factor	NA	NA	NA	NA
VEG93193.1\|662056_662650_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	1.4e-55	55.6
VEG93194.1\|662662_663916_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.2e-140	62.1
VEG93195.1\|663981_666291_+\|protease	Lon protease 1	A0A0R6PGP8	Moraxella_phage	6.5e-178	44.4
VEG93196.1\|666290_666989_+	Probable GTP-binding protein EngB	NA	NA	NA	NA
VEG93197.1\|666985_667957_+	Octaprenyl-diphosphate synthase	A0A1V0SE37	Indivirus	1.9e-06	23.5
VEG93198.1\|667958_668849_+	Sec-independent protein translocase protein TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	1.1e-19	29.2
VEG93199.1\|668870_671528_+\|tRNA	Valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	2.2e-169	41.5

DBSCAN-SWA_3

729690 : 738013

uncultured_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEG93253.1\|729690_730731_+	Recombinase A	A0A0S2MVG1	Bacillus_phage	9.6e-121	63.6
VEG93254.1\|730748_731177_+	recombination regulator RecX	NA	NA	NA	NA
VEG93255.1\|731352_732897_+	Ribonuclease Y	NA	NA	NA	NA
VEG93256.1\|733148_734921_+	DNA primase	A0A0K1LMQ9	Caulobacter_phage	1.6e-54	35.8
VEG93257.1\|734944_736108_+	Sigma-A	F4YCU2	Synechococcus_phage	4.2e-40	37.6
VEG93258.1\|736290_736629_+	6-carboxy-5,6,7,8-tetrahydropterin synthase	S4U060	uncultured_phage	2.6e-43	69.6
VEG93259.1\|736615_737359_+	7-carboxy-7-deazaguanine synthase	S4TZT1	uncultured_phage	1.8e-52	46.2
VEG93260.1\|737449_738013_+	GTP cyclohydrolase 1	S4U0J3	uncultured_phage	1.3e-63	70.3

DBSCAN-SWA_4

961660 : 977930

Clostridium_phage(50.0%)

portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEG93473.1\|961660_963049_+	phage uncharacterized protein, C-terminal domain	A0A1S5SAN3	Streptococcus_phage	2.6e-158	60.3
VEG93474.1\|963063_964467_+\|portal	phage portal protein, SPP1 family	A0A0A7S074	Clostridium_phage	7.5e-60	33.9
VEG93475.1\|964469_965465_+	NAD+--asparagine ADP-ribosyltransferase	S5MTV5	Brevibacillus_phage	6.7e-47	33.6
VEG93476.1\|965596_966190_+	Phage minor structural protein GP20	A0A2I7QIR1	Bacillus_phage	1.2e-11	32.7
VEG93477.1\|966215_967064_+	Uncharacterised protein	X2KPH5	Streptococcus_phage	1.1e-42	37.5
VEG93478.1\|967078_967444_+	Uncharacterised protein	NA	NA	NA	NA
VEG93479.1\|967419_967797_+	Uncharacterised protein	S5MBV4	Brevibacillus_phage	9.1e-05	36.0
VEG93480.1\|967789_968248_+	Uncharacterised protein	Q20DD1	Lactobacillus_phage	7.4e-09	37.3
VEG93481.1\|968247_968706_+	Uncharacterised protein	NA	NA	NA	NA
VEG93482.1\|968683_968944_+	Uncharacterised protein	NA	NA	NA	NA
VEG93483.1\|968970_970326_+\|tail	Phage tail sheath protein	A0A0A8WIF0	Clostridium_phage	1.2e-107	46.2
VEG93484.1\|970337_970823_+	Protein of uncharacterised function (DUF2001)	A0A0A8WJ62	Clostridium_phage	6.8e-21	35.0
VEG93485.1\|970882_971311_+	Phage XkdN-like protein	NA	NA	NA	NA
VEG93486.1\|971498_973478_+\|tail	Phage-related minor tail protein	S6AVU8	Thermus_phage	2.9e-49	34.4
VEG93487.1\|973477_974188_+	Uncharacterised protein	A0A0A8WFE5	Clostridium_phage	2.2e-20	35.2
VEG93488.1\|974163_976020_+	Uncharacterised protein	X5JAJ3	Clostridium_phage	4.6e-17	38.1
VEG93489.1\|976019_976433_+	Protein of uncharacterised function (DUF2577)	NA	NA	NA	NA
VEG93490.1\|976432_976861_+	Protein of uncharacterised function (DUF2634)	A0A0A8WFW6	Clostridium_phage	9.3e-30	56.2
VEG93491.1\|976847_977930_+	Uncharacterized homolog of phage Mu protein gp47	A0A0A8WJT7	Clostridium_phage	1.4e-58	37.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134375

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection