CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LR134295	Escherichia coli strain NCTC9080 genome assembly, chromosome: 1	6 crisprs	csa3,PD-DExK,cas3,cas8e,cse2gr11,cas7,cas5,cas6e,cas1,cas2,DEDDh,WYL,DinG,c2c9_V-U4,RT	0	19	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LR134295_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134295_1

995236-995629

Unclear

I-E

Consensus_repeat	Method
GTGTTCCCCGCGCCAGCGGGGATAAACC	PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACC	CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACC	CRT

6 spacers

The CRISPR arrays of LR134295_1

>merge|LR134295|1|995236-995629|PILER-CR,CRISPRCasFinder,CRT
GTGTTCCCCGCGCCAGCGGGGATAAACCGCGGCCCATAATATTAATATAATCCACATGAGGGTGTTCCCCGCGCCAGCGGGGATAAACCGCATATCAAGAATTTATGGACTCGGGTGGCAAAGTGTTCCCCGCGCCAGCGGGGATAAACCGGCAAAAACCGGGCAATCGCAAAAAGGCGTAATGTGTTCCCCGCGCCAGCGGGGATAAACCTGTGTTTGCGGCATTAACGCTCACCAGCATTTCGTGTTCCCCGCGCCAGCGGGGATAAACCGAATAGCAATAGTCCATAGATTTGCGAAAACAGGTGTTCCCCGCGCCAGCGGGGATAAACCGGAGCCTGACGAGACTACTGAGGCCGTTCTGTCGAGTTCCCCGCGCCAGCGGGGATAAACC

>LR134295|1|1|995236-995629|PILER-CR
GTGTTCCCCGCGCCAGCGGGGATAAACC	GCGGCCCATAATATTAATATAATCCACATGAGG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GCATATCAAGAATTTATGGACTCGGGTGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGCAAAAACCGGGCAATCGCAAAAAGGCGTAAT
GTGTTCCCCGCGCCAGCGGGGATAAACC	TGTGTTTGCGGCATTAACGCTCACCAGCATTTC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACC

>LR134295|1|1|995236-995629|CRISPRCasFinder
GTGTTCCCCGCGCCAGCGGGGATAAACC	GCGGCCCATAATATTAATATAATCCACATGAGG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GCATATCAAGAATTTATGGACTCGGGTGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGCAAAAACCGGGCAATCGCAAAAAGGCGTAAT
GTGTTCCCCGCGCCAGCGGGGATAAACC	TGTGTTTGCGGCATTAACGCTCACCAGCATTTC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACC

>LR134295|1|1|995236-995629|CRT
GTGTTCCCCGCGCCAGCGGGGATAAACC	GCGGCCCATAATATTAATATAATCCACATGAGG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GCATATCAAGAATTTATGGACTCGGGTGGCAAA
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGCAAAAACCGGGCAATCGCAAAAAGGCGTAAT
GTGTTCCCCGCGCCAGCGGGGATAAACC	TGTGTTTGCGGCATTAACGCTCACCAGCATTTC
GTGTTCCCCGCGCCAGCGGGGATAAACC	GAATAGCAATAGTCCATAGATTTGCGAAAACAG
GTGTTCCCCGCGCCAGCGGGGATAAACC	GGAGCCTGACGAGACTACTGAGGCCGTTCTGTC
GAGTTCCCCGCGCCAGCGGGGATAAACC

Protein	Signature genes	Signature genes Name	Protein_function
LR134295.1\|VEE27188.1\|999369_1000155_+\|putative-short-chain-dehydrogenase	unknown	unknown	gnl\|CDD\|187605
LR134295.1\|VEE27196.1\|1003863_1004724_+\|electron-transfer-flavoprotein-subunit-YgcQ	unknown	unknown	gnl\|CDD\|224936
LR134295.1\|VEE27166.1\|985991_988226_+\|GTP-pyrophosphokinase	unknown	unknown	gnl\|CDD\|182797
LR134295.1\|VEE27198.1\|1004871_1005447_-\|glycerol-antiterminator-regulatory-protein	unknown	unknown	gnl\|CDD\|224865
LR134295.1\|VEE27168.1\|988303_988552_+\|antitoxin-MazE	unknown	unknown	gnl\|CDD\|182082
LR134295.1\|VEE27178.1\|993059_993932_-\|protein	unknown	unknown	gnl\|CDD\|224429
LR134295.1\|VEE27164.1\|984642_985944_+\|23s-rRNA-(uracil-5-)-methyltransferase	unknown	unknown	gnl\|CDD\|237291
LR134295.1\|VEE27194.1\|1003087_1003867_+\|electron-transfer-flavoprotein-subunit-YgcR	unknown	unknown	gnl\|CDD\|224997
LR134295.1\|VEE27190.1\|1000224_1001679_+\|putative-FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
LR134295.1\|VEE27182.1\|994224_994896_+\|7-carboxy-7-deazaguanine-synthase;-queosine-biosynthesis	unknown	unknown	gnl\|CDD\|275126
LR134295.1\|VEE27186.1\|997773_999051_-\|major-facilitator-superfamily-protein	unknown	unknown	gnl\|CDD\|349949
LR134295.1\|VEE27170.1\|988551_988887_+\|toxin-ChpA	unknown	unknown	gnl\|CDD\|182138
LR134295.1\|VEE27176.1\|991701_993000_+\|enolase	unknown	unknown	gnl\|CDD\|234617
LR134295.1\|VEE27202.1\|1005714_1006986_-\|putative-FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182194
LR134295.1\|VEE27200.1\|1005463_1005724_-\|ferredoxin-like-protein-YgcO	unknown	unknown	gnl\|CDD\|225289
LR134295.1\|VEE27184.1\|996268_997747_-\|putative-sugar-kinase	unknown	unknown	gnl\|CDD\|212662
LR134295.1\|VEE27180.1\|993945_994086_-\|small-protein-involved-in-the-cell-envelope-stress-response	unknown	unknown	unknown
LR134295.1\|VEE27192.1\|1001700_1003110_+\|major-facilitator-superfamily-protein	unknown	unknown	gnl\|CDD\|340929
LR134295.1\|VEE27174.1\|989976_991614_+\|CTP-synthetase	unknown	unknown	gnl\|CDD\|235437
LR134295.1\|VEE27172.1\|988957_989749_+\|nucleoside-triphosphate-pyrophosphohydrolase	unknown	unknown	gnl\|CDD\|236569

Protein	Function_ID	Function_description	E-value
LR134295.1\|VEE27188.1\|999369_1000155_+\|putative-short-chain-dehydrogenase	gnl\|CDD\|187605	cd05347, Ga5DH-like_SDR_c, gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs. Ga5DH catalyzes the NADP-dependent conversion of carbon source D-gluconate and 5-keto-D-gluconate. This SDR subgroup has a classical Gly-rich NAD(P)-binding motif and a conserved active site tetrad pattern. However, it has been proposed that Arg104 (Streptococcus suis Ga5DH numbering), as well as an active site Ca2+, play a critical role in catalysis. In addition to Ga5DHs this subgroup contains Erwinia chrysanthemi KduD which is involved in pectin degradation, and is a putative 2,5-diketo-3-deoxygluconate dehydrogenase. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107,15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.84461e-140
LR134295.1\|VEE27196.1\|1003863_1004724_+\|electron-transfer-flavoprotein-subunit-YgcQ	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	7.42017e-90
LR134295.1\|VEE27166.1\|985991_988226_+\|GTP-pyrophosphokinase	gnl\|CDD\|182797	PRK10872, relA, (p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional.	0
LR134295.1\|VEE27198.1\|1004871_1005447_-\|glycerol-antiterminator-regulatory-protein	gnl\|CDD\|224865	COG1954, GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription].	5.83077e-88
LR134295.1\|VEE27168.1\|988303_988552_+\|antitoxin-MazE	gnl\|CDD\|182082	PRK09798, PRK09798, MazF-MazE toxin-antitoxin system antitoxin MazE.	6.19513e-48
LR134295.1\|VEE27178.1\|993059_993932_-\|protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	3.25867e-100
LR134295.1\|VEE27164.1\|984642_985944_+\|23s-rRNA-(uracil-5-)-methyltransferase	gnl\|CDD\|237291	PRK13168, rumA, 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD.	0
LR134295.1\|VEE27194.1\|1003087_1003867_+\|electron-transfer-flavoprotein-subunit-YgcR	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	1.56693e-62
LR134295.1\|VEE27190.1\|1000224_1001679_+\|putative-FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	2.73778e-83
LR134295.1\|VEE27182.1\|994224_994896_+\|7-carboxy-7-deazaguanine-synthase;-queosine-biosynthesis	gnl\|CDD\|275126	TIGR04322, organic_radical_activating_enzyme, putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE. Members of this radical SAM domain protein family appear to be the E. coli form of the queuosine biosynthesis protein QueE. QueE is involved in making preQ0 (7-cyano-7-deazaquanine), a precursor of both the bacterial/eukaryotic modified tRNA base queuosine and the archaeal modified base archaeosine. Members occur in species that lack known forms of QueE but usually are not found in queuosine biosynthesis operons. Members of this family tend to form bi-directional best hit matches to members of known (TIGR03365) and putative (TIGR03963) QueE families from other lineages.	3.98248e-155
LR134295.1\|VEE27186.1\|997773_999051_-\|major-facilitator-superfamily-protein	gnl\|CDD\|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	1.60446e-29
LR134295.1\|VEE27170.1\|988551_988887_+\|toxin-ChpA	gnl\|CDD\|182138	PRK09907, PRK09907, endoribonuclease MazF.	1.17475e-74
LR134295.1\|VEE27176.1\|991701_993000_+\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
LR134295.1\|VEE27202.1\|1005714_1006986_-\|putative-FAD-dependent-oxidoreductase	gnl\|CDD\|182194	PRK10015, PRK10015, oxidoreductase; Provisional.	9.16926e-127
LR134295.1\|VEE27200.1\|1005463_1005724_-\|ferredoxin-like-protein-YgcO	gnl\|CDD\|225289	COG2440, FixX, Ferredoxin-like protein [Energy production and conversion].	1.81311e-41
LR134295.1\|VEE27184.1\|996268_997747_-\|putative-sugar-kinase	gnl\|CDD\|212662	cd07779, FGGY_ygcE_like, uncharacterized ygcE-like proteins. This subfamily consists of uncharacterized hypothetical bacterial proteins with similarity to Escherichia coli sugar kinase ygcE , whose functional roles are not yet clear. Escherichia coli ygcE is recognized by this model, but is not present in the alignment as it contains a deletion relative to other members of the group. These proteins belong to the FGGY family of carbohydrate kinases, the monomers of which contain two large domains, which are separated by a deep cleft that forms the active site. This model includes both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain.	1.27376e-109
LR134295.1\|VEE27172.1\|988957_989749_+\|nucleoside-triphosphate-pyrophosphohydrolase	gnl\|CDD\|236569	PRK09562, mazG, nucleoside triphosphate pyrophosphohydrolase; Reviewed.	8.97718e-160
LR134295.1\|VEE27192.1\|1001700_1003110_+\|major-facilitator-superfamily-protein	gnl\|CDD\|340929	cd17371, MFS_MucK, Cis,cis-muconate transport protein and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Acinetobacter sp. Cis,cis-muconate transport protein (MucK), Escherichia coli putative sialic acid transporter 1, and similar proteins. MucK functions in the uptake of muconate and allows Acinetobacter calcoaceticus ADP1 (BD413) to grow on exogenous cis,cis-muconate as the sole carbon source. The MucK subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.50431e-51
LR134295.1\|VEE27174.1\|989976_991614_+\|CTP-synthetase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0

>LR134295.1|VEE27182.1|994224_994896_+|7-carboxy-7-deazaguanine-synthase;-queosine-biosynthesis
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKHPVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>LR134295.1|VEE27180.1|993945_994086_-|small-protein-involved-in-the-cell-envelope-stress-response
MSEENKENGFNHVKTFTKIIFIFSVLVFNDNEYKITDAAVNLFIQI
>LR134295.1|VEE27178.1|993059_993932_-|protein
MRYFILMFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKELTHKLESIFNNTQVQIAVLIVPTTKDETIEQYATRVFDNWRLGDAKRNDGILIVVAWSDRTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAKGLELAINALNNQLTSQHQYPTNPSESESASSSDHYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSGVCISAIYLLDLFLFSDKIFSIAVFSFFFTFTIFMVFTCLCVLQKRASGRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGASGRW
>LR134295.1|VEE27176.1|991701_993000_+|enolase
MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA
>LR134295.1|VEE27174.1|989976_991614_+|CTP-synthetase
MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRKERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQMAVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPANERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEWEQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVETRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARHVANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVDDSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPWFVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK
>LR134295.1|VEE27172.1|988957_989749_+|nucleoside-triphosphate-pyrophosphohydrolase
MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVLDAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFADSSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL
>LR134295.1|VEE27170.1|988551_988887_+|toxin-ChpA
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
>LR134295.1|VEE27168.1|988303_988552_+|antitoxin-MazE
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW
>LR134295.1|VEE27166.1|985991_988226_+|GTP-pyrophosphokinase
MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQQTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKSVVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHLREVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLLHERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDVRAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTVEIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGEMLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVPFTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAGRQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNKPSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGFITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRDITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARRLHGS
>LR134295.1|VEE27164.1|984642_985944_+|23s-rRNA-(uracil-5-)-methyltransferase
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHDVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVKQCPILAPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>LR134295.1|VEE27184.1|996268_997747_-|putative-sugar-kinase
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSEDAAVMDKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDNMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHTDVILKKSYEVMHGELGNVDSIQSWSNA
>LR134295.1|VEE27186.1|997773_999051_-|major-facilitator-superfamily-protein
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQIAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFSRFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLTLTALLVTNSNPQSVAMGIGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWLMGMAALGMVIVFTFLLFQKIRTADSAPAMASSK
>LR134295.1|VEE27188.1|999369_1000155_+|putative-short-chain-dehydrogenase
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR
>LR134295.1|VEE27190.1|1000224_1001679_+|putative-FAD-binding-oxidoreductase
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRSIGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKVTGEGIAEIVARYPQCQRVDSKLIETWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIYPIEK
>LR134295.1|VEE27192.1|1001700_1003110_+|major-facilitator-superfamily-protein
MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRIAALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFSPRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLFSSRYWRRTAFNSVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQVTLLLLATVLLVGFVVTWLWAPETKALPLVAAGNVGGANEHSVSV
>LR134295.1|VEE27194.1|1003087_1003867_+|electron-transfer-flavoprotein-subunit-YgcR
MNILLAFKAEPDAGMLAEKEWQAAAQGKSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEEAVLLETAADLRFAPEFVARHIAEWQHQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDALFITLEQRTEHGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAEMPAMQCLQLARAEQRRGATLIDGQTVAEKAQKLWQDYLRQRMQP
>LR134295.1|VEE27196.1|1003863_1004724_+|electron-transfer-flavoprotein-subunit-YgcQ
MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQVLDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHWGNALTATLQTEKRPLCLSLARQAGAAKNATLPSGMQQLNIVPGALPDWLVSTEDLKNVTRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISGHLLAPEVCIVVGASGAAALMAGVRNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEALVTNIHADCQ
>LR134295.1|VEE27198.1|1004871_1005447_-|glycerol-antiterminator-regulatory-protein
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISNIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVCDEEDARNAINAGVVALSTTNTGVWTLAKKLL
>LR134295.1|VEE27200.1|1005463_1005724_-|ferredoxin-like-protein-YgcO
MSVARNLWRVADAPHIVPADSVERQTAERLINACPAGLFSLTPEGDLRIDYRSCLECGTCRLLCDESTLQQWRYPPSGFGITYRFG
>LR134295.1|VEE27202.1|1005714_1006986_-|putative-FAD-dependent-oxidoreductase
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEEEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIKEVLSLEPSAIEERFHLENNEGAALLFSGRICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQSRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSLRCL

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Crispr_ID: LR134295_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134295_2

1021179-1022366

TypeI-E

I-E

Consensus_repeat	Method
GAGTTCCCCGCGCCAGCGGGGATAAACCG	PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CRT

19 spacers

cas2,cas1,cas6e,cas5,cas7,cse2gr11,cas8e,cas3

The CRISPR arrays of LR134295_2

>merge|LR134295|2|1021179-1022366|PILER-CR,CRISPRCasFinder,CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCGACAATCCCACGCCGATAATCTCTATACAGCAAGAGTTCCCCGCGCCAGCGGGGATAAACCGGGCACGGAATTGTTATGCTGTTCCCCTGACCGGAGTTCCCCGCGCCAGCGGGGATAAACCGATCCGCCGCCGGTTAACGCTGGACCAGTTCCGGAGTTCCCCGCGCCAGCGGGGATAAACCGGGCGAGTCCGTCAGCGGTGCGCCGCTGCAACAGAGTTCCCCGCGCCAGCGGGGATAAACCGGGACAATGTGAAAAGCTTAATATTCATTACATGAGTTCCCCGCGCCAGCGGGGATAAACCGCGACGTTTTCTAATATCACCCAGCAATCAATTGAGTTCCCCGCGCCAGCGGGGATAAACCGATTTCATCAAAGCATTAAGGGATGGAATAAAGGAGTTCCCCGCGCCAGCGGGGATAAACCGTCATGAATATGGGGAAAACGAACAATCTGTTTGAGTTCCCCGCGCCAGCGGGGATAAACCGATGACCATTGGTGAACGCATCCGCTTTCGCCGGAGTTCCCCGCGCCAGCGGGGATAAACCGCCGACGTGGGGATTTACTGCCACGCATAAAAAGAGTTCCCCGCGCCAGCGGGGATAAACCGTACAGTTTCCATAAATTCACCTCGTTTATATAGAGTTCCCCGCGCCAGCGGGGATAAACCGATCGGACGATGGCGATCGCAATCGCGCGGGAAGAGTTCCCCGCGCCAGCGGGGATAAACCGAGGACGAAACGACCGGAAAACTGGCGACGGGCGAGTTCCCCGCGCCAGCGGGGATAAACCGAACCTTGTCGGGTCGCCCGTGCGTCATGATGAGAGTTCCCCGCGCCAGCGGGGATAAACCGCCAGCCGAAACAACGCCAGCAAAATCGACCGCGAGTTCCCCGCGCCAGCGGGGATAAACCGGGATATAGAGCGGGTACTCGAGCGAAGCGGGGGAGTTCCCCGCGCCAGCGGGGATAAACCGCCAGGACAGGCCGTGACGGTTGCCATTGAGTCGAGTTCCCCGCGCCAGCGGGGATAAACCGTTTTTGTTCTCTTCAAAACGCCGAACAACCAAGAGTTCCCCGCGTCAGCGAGGATAAACCGGACGCACTGGATGCGATGATGGATATCACTTGGAGTTCCCCGCCCCTGCGGTAGAACTCCC

>LR134295|2|2|1021179-1022244|PILER-CR
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ACAATCCCACGCCGATAATCTCTATACAGCAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGCACGGAATTGTTATGCTGTTCCCCTGACCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATCCGCCGCCGGTTAACGCTGGACCAGTTCCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGCGAGTCCGTCAGCGGTGCGCCGCTGCAACA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGACAATGTGAAAAGCTTAATATTCATTACAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CGACGTTTTCTAATATCACCCAGCAATCAATT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATTTCATCAAAGCATTAAGGGATGGAATAAAG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCATGAATATGGGGAAAACGAACAATCTGTTT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATGACCATTGGTGAACGCATCCGCTTTCGCCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCGACGTGGGGATTTACTGCCACGCATAAAAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TACAGTTTCCATAAATTCACCTCGTTTATATA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATCGGACGATGGCGATCGCAATCGCGCGGGAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AGGACGAAACGACCGGAAAACTGGCGACGGGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AACCTTGTCGGGTCGCCCGTGCGTCATGATGA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGCCGAAACAACGCCAGCAAAATCGACCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGATATAGAGCGGGTACTCGAGCGAAGCGGGG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGGACAGGCCGTGACGGTTGCCATTGAGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG

>LR134295|2|2|1021179-1022366|CRISPRCasFinder
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ACAATCCCACGCCGATAATCTCTATACAGCAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGCACGGAATTGTTATGCTGTTCCCCTGACCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATCCGCCGCCGGTTAACGCTGGACCAGTTCCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGCGAGTCCGTCAGCGGTGCGCCGCTGCAACA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGACAATGTGAAAAGCTTAATATTCATTACAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CGACGTTTTCTAATATCACCCAGCAATCAATT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATTTCATCAAAGCATTAAGGGATGGAATAAAG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCATGAATATGGGGAAAACGAACAATCTGTTT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATGACCATTGGTGAACGCATCCGCTTTCGCCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCGACGTGGGGATTTACTGCCACGCATAAAAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TACAGTTTCCATAAATTCACCTCGTTTATATA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATCGGACGATGGCGATCGCAATCGCGCGGGAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AGGACGAAACGACCGGAAAACTGGCGACGGGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AACCTTGTCGGGTCGCCCGTGCGTCATGATGA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGCCGAAACAACGCCAGCAAAATCGACCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGATATAGAGCGGGTACTCGAGCGAAGCGGGG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGGACAGGCCGTGACGGTTGCCATTGAGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTTGTTCTCTTCAAAACGCCGAACAACCAA
GAGTTCCCCGCGTCAGCGAGGATAAACCG	GACGCACTGGATGCGATGATGGATATCACTTG
GAGTTCCCCGCCCCTGCGGTAGAACTCCC

>LR134295|2|2|1021179-1022366|CRT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ACAATCCCACGCCGATAATCTCTATACAGCAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGCACGGAATTGTTATGCTGTTCCCCTGACCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATCCGCCGCCGGTTAACGCTGGACCAGTTCCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGCGAGTCCGTCAGCGGTGCGCCGCTGCAACA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGACAATGTGAAAAGCTTAATATTCATTACAT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CGACGTTTTCTAATATCACCCAGCAATCAATT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATTTCATCAAAGCATTAAGGGATGGAATAAAG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TCATGAATATGGGGAAAACGAACAATCTGTTT
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATGACCATTGGTGAACGCATCCGCTTTCGCCG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCGACGTGGGGATTTACTGCCACGCATAAAAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TACAGTTTCCATAAATTCACCTCGTTTATATA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	ATCGGACGATGGCGATCGCAATCGCGCGGGAA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AGGACGAAACGACCGGAAAACTGGCGACGGGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	AACCTTGTCGGGTCGCCCGTGCGTCATGATGA
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGCCGAAACAACGCCAGCAAAATCGACCGC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	GGATATAGAGCGGGTACTCGAGCGAAGCGGGG
GAGTTCCCCGCGCCAGCGGGGATAAACCG	CCAGGACAGGCCGTGACGGTTGCCATTGAGTC
GAGTTCCCCGCGCCAGCGGGGATAAACCG	TTTTTGTTCTCTTCAAAACGCCGAACAACCAA
GAGTTCCCCGCGTCAGCGAGGATAAACCG	GACGCACTGGATGCGATGATGGATATCACTTG
GAGTTCCCCGCCCCTGCGGTAGAACTCCC

Protein	Signature genes	Signature genes Name	Protein_function
LR134295.1\|VEE27246.1\|1029730_1030492_+\|stationary-phase-survival-protein-SurE	unknown	unknown	gnl\|CDD\|234732
LR134295.1\|VEE27230.1\|1023675_1024584_+\|sulfate-adenylyltransferase	unknown	unknown	gnl\|CDD\|235375
LR134295.1\|VEE27220.1\|1018593_1019268_+\|CRISPR-associated-Cas5-family-Ecoli-subtype-protein	cas5	cd09645_cas5_CAS-I-E	gnl\|CDD\|273842
LR134295.1\|VEE27222.1\|1019254_1019854_+\|CRISPR-associated-Cse3-family-protein	cas6e	cd09664_cas6e_CAS-I-E	gnl\|CDD\|273869
LR134295.1\|VEE27238.1\|1027184_1027496_+\|cell-division-protein	unknown	unknown	gnl\|CDD\|179156
LR134295.1\|VEE27224.1\|1019869_1020787_+\|putative-CRISPR-associated-protein-Cas1	cas1	cd09719_cas1_CAS-I-E	gnl\|CDD\|274693
LR134295.1\|VEE27210.1\|1011329_1012064_+\|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl\|CDD\|234997
LR134295.1\|VEE27208.1\|1009543_1011256_+\|sulfite-reductase-(NADPH)-hemoprotein-beta-subunit	unknown	unknown	gnl\|CDD\|237402
LR134295.1\|VEE27212.1\|1012422_1015089_+\|CRISPR-associated-helicase-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|182031
LR134295.1\|VEE27226.1\|1020788_1021073_+\|CRISPR-associated-protein-Cas2	cas2	cd09648_cas2_CAS-I-E	gnl\|CDD\|236930
LR134295.1\|VEE27240.1\|1027514_1028225_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|234670
LR134295.1\|VEE27234.1\|1026012_1026618_+\|adenosine-5-phosphosulfate-kinase	unknown	unknown	gnl\|CDD\|179661
LR134295.1\|VEE27214.1\|1015503_1017012_+\|Cse1-family-CRISPR-associated-protein	cas8e	cd09669_cas8e_CAS-I-E	gnl\|CDD\|236613
LR134295.1\|VEE27218.1\|1017499_1018591_+\|CRISPR-associated-Cse4-family-protein	cas7	cd09646_cas7_CAS-I-E	gnl\|CDD\|273843
LR134295.1\|VEE27244.1\|1028700_1029750_+\|tRNA-pseudouridine-synthase-D	unknown	unknown	gnl\|CDD\|234884
LR134295.1\|VEE27228.1\|1022386_1023424_-\|alkaline-phosphatase-isozyme-conversion-protein	unknown	unknown	gnl\|CDD\|182299
LR134295.1\|VEE27216.1\|1017004_1017487_+\|CRISPR-associated-Cse2-family-protein	cse2gr11	cd09670_cse2gr11_CAS-I-E	gnl\|CDD\|187801
LR134295.1\|VEE27236.1\|1026667_1026991_+\|putative-cytochrome-oxidase-subunit	unknown	unknown	gnl\|CDD\|371891
LR134295.1\|VEE27242.1\|1028224_1028704_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl\|CDD\|178851
LR134295.1\|VEE27232.1\|1024585_1026013_+\|sulfate-adenylyltransferase	unknown	unknown	gnl\|CDD\|235349

Protein	Function_ID	Function_description	E-value
LR134295.1\|VEE27246.1\|1029730_1030492_+\|stationary-phase-survival-protein-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.92279e-150
LR134295.1\|VEE27230.1\|1023675_1024584_+\|sulfate-adenylyltransferase	gnl\|CDD\|235375	PRK05253, PRK05253, sulfate adenylyltransferase subunit CysD.	0
LR134295.1\|VEE27220.1\|1018593_1019268_+\|CRISPR-associated-Cas5-family-Ecoli-subtype-protein	gnl\|CDD\|273842	TIGR01868, hypothetical_protein, CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is part of the ECOLI subtype CRISPR/Cas locus, and now characterized as part of the CASCADE complex of that system. It shares a small N-terminal homology region with members of several other CRISPR/Cas subtypes, and we view the families that share this region as being Cas5.	6.70134e-100
LR134295.1\|VEE27222.1\|1019254_1019854_+\|CRISPR-associated-Cse3-family-protein	gnl\|CDD\|273869	TIGR01907, CRISPR_system_Cascade_subunit_CasE, CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model family, represented by CT1974 from Chlorobium tepidum, is found in the Ecoli subtype of CRISPR/Cas regions and is designated Cse3 (CRISPR/Cas Subtype Ecoli protein 3). The representative of this family from Thermus thermophilus HB8 (TTHB192) has been crystallized and found to have a structure consisting of two domains with opposing parallel beta-sheets known as a beta-sheet platform. This structure is similar to those found in the Sex-lethal protein and poly(A)-binding protein. This structure is consistent with an RNA-binding function.	4.3792e-101
LR134295.1\|VEE27238.1\|1027184_1027496_+\|cell-division-protein	gnl\|CDD\|179156	PRK00888, ftsB, cell division protein FtsB; Reviewed.	5.55235e-62
LR134295.1\|VEE27224.1\|1019869_1020787_+\|putative-CRISPR-associated-protein-Cas1	gnl\|CDD\|274693	TIGR03638, cas1_ECOLI, CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the ECOLI subtype of CRISPR/Cas system.	3.34057e-159
LR134295.1\|VEE27210.1\|1011329_1012064_+\|phosphoadenosine-phosphosulfate-reductase	gnl\|CDD\|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	6.7075e-138
LR134295.1\|VEE27208.1\|1009543_1011256_+\|sulfite-reductase-(NADPH)-hemoprotein-beta-subunit	gnl\|CDD\|237402	PRK13504, PRK13504, NADPH-dependent assimilatory sulfite reductase hemoprotein subunit.	0
LR134295.1\|VEE27212.1\|1012422_1015089_+\|CRISPR-associated-helicase-Cas3	gnl\|CDD\|182031	PRK09694, PRK09694, CRISPR-associated helicase/endonuclease Cas3.	0
LR134295.1\|VEE27226.1\|1020788_1021073_+\|CRISPR-associated-protein-Cas2	gnl\|CDD\|236930	PRK11558, PRK11558, putative ssRNA endonuclease; Provisional.	1.46262e-62
LR134295.1\|VEE27240.1\|1027514_1028225_+\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	3.26939e-121
LR134295.1\|VEE27234.1\|1026012_1026618_+\|adenosine-5-phosphosulfate-kinase	gnl\|CDD\|179661	PRK03846, PRK03846, adenylylsulfate kinase; Provisional.	7.34447e-148
LR134295.1\|VEE27214.1\|1015503_1017012_+\|Cse1-family-CRISPR-associated-protein	gnl\|CDD\|236613	PRK09693, PRK09693, Cascade antiviral complex protein; Validated.	0
LR134295.1\|VEE27218.1\|1017499_1018591_+\|CRISPR-associated-Cse4-family-protein	gnl\|CDD\|273843	TIGR01869, CRISPR_system_Cascade_subunit_CasC, CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This family is represented by CT1975 of Chlorobium tepidum and is part of the Ecoli subtype of CRISPR/Cas locis. It is designated Cse4, for CRISPR/Cas Subtype Ecoli protein 4.	3.0298e-151
LR134295.1\|VEE27244.1\|1028700_1029750_+\|tRNA-pseudouridine-synthase-D	gnl\|CDD\|234884	PRK00984, truD, tRNA pseudouridine synthase D; Reviewed.	0
LR134295.1\|VEE27228.1\|1022386_1023424_-\|alkaline-phosphatase-isozyme-conversion-protein	gnl\|CDD\|182299	PRK10199, PRK10199, alkaline phosphatase isozyme conversion aminopeptidase; Provisional.	0
LR134295.1\|VEE27216.1\|1017004_1017487_+\|CRISPR-associated-Cse2-family-protein	gnl\|CDD\|187801	cd09670, Cse2_I-E, CRISPR/Cas system-associated protein Cse2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Small alpha-helical protein; also known as Cse2/CasB/YgcK family; specific gene for I-E subtype;.	2.83779e-33
LR134295.1\|VEE27236.1\|1026667_1026991_+\|putative-cytochrome-oxidase-subunit	gnl\|CDD\|371891	pfam12084, DUF3561, Protein of unknown function (DUF3561). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are about 110 amino acids in length.	1.22003e-52
LR134295.1\|VEE27242.1\|1028224_1028704_+\|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl\|CDD\|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.56248e-104
LR134295.1\|VEE27232.1\|1024585_1026013_+\|sulfate-adenylyltransferase	gnl\|CDD\|235349	PRK05124, cysN, sulfate adenylyltransferase subunit 1; Provisional.	0

>LR134295.1|VEE27226.1|1020788_1021073_+|CRISPR-associated-protein-Cas2
MSMLVVVTENVPPRLRGRLAIWLLEVRAGVYVGDVSAKIREMIWEQIAGLAEEGNVVMAWATNTESGFEFQTFGVNRRTPVDLDGLRLVSFLPV
>LR134295.1|VEE27224.1|1019869_1020787_+|putative-CRISPR-associated-protein-Cas1
MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRRYDPKDWEKGDTVNQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPEDAQPVAIPLPVSLGDAGHRSS
>LR134295.1|VEE27222.1|1019254_1019854_+|CRISPR-associated-Cse3-family-protein
MYLSKVIIARAWSRDLYQLHQGLWHLFPNRPDAARDFLFHVEKRNTPEGCHVLLQSAQMPVSTAVATVIKTKQVEFQLQVGVPLYFRLRANPIKTILDNQKRLDSKGNIKRCRVPLIKEAEQIAWLQRKLGNAARVEDVHPISERPQYFSGDGKSGKIQTVCFEGVITINDAPALIDLVQQGIGPAKSMGCGLLSLAPL
>LR134295.1|VEE27220.1|1018593_1019268_+|CRISPR-associated-Cas5-family-Ecoli-subtype-protein
MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACLGIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHETIQTWREYLCDASFTVALWLTPQATMVMSELEKAVLKPRYTPYLGRRSCPLTQPLFLGTCQASDPQKVLLNYEPVGGDIYSEESVDGHHLKFTVRDEPMITLPRQFASREWYVIKGGMDVSQ
>LR134295.1|VEE27218.1|1017499_1018591_+|CRISPR-associated-Cse4-family-protein
MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSLKRAMRKSDYYAQNIGESSLRTIHLAQLRDVLRQKLSERFDQKIIDKTLALLSGKSVDEAEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDIALSGRMATSGMMSELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQEQGSAHLGTQEFSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPADMVMVNFSDMPLSMANAFEKAVKANDGFLQPSLQAFNQYWDRVANGYGLNGAAAQFSLSDVDPITGQVQQMPTLEQLKSWVRNNGEA
>LR134295.1|VEE27216.1|1017004_1017487_+|CRISPR-associated-Cse2-family-protein
MADEIDAMALYRAWQQLDNGACAQIRRVSEPDELRDIPAFYRLVQPFGWENPRHQQALLRMVFCLSAGKNVIRHQDKKPEQTTGISLGRALANSGRINERRIFQLIRADRTADMVQLRRLLAHAEPVLDWPLMARMLTWWGKRERQQLLEDFVLTTNKNA
>LR134295.1|VEE27214.1|1015503_1017012_+|Cse1-family-CRISPR-associated-protein
MNLLIDNWIPVRPRNGGKVQIINLQSLYCSRDQWRLSLPRDDMELAALALLVCIGQIIDPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQTKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQANQAPGFGGGFKSGLRGGTPITTFVRGIDLRSTVLLNVLTIPRLQKQFPNESHTENQPTWVKPVKPNESVPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKEKFTFTVNGLWPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDKIIQNENGNRVAAVVNQFRNIAPQSPLELIMGGYRNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQSELLIPDVLANVNFSQADEVIADLRDKLHQLCEMLFNQSVAPYAHHPKLISTLALARATLYKHLRELKPQGGPSNG
>LR134295.1|VEE27212.1|1012422_1015089_+|CRISPR-associated-helicase-Cas3
MEPFKYICHYWGKSSKSLTKGNDIHLLIYHCLDVAAVADCWWDQSVVLQNTFCRNEMLSKQRVKAWLLFFIALHDIGKFDIRFQYKSAESWLKLNPATPSLNGPSTQMCRKFNHGAAGLYWFNQDSLSEQSLGDFFSFFDAAPHPYESWFPWVEAVTGHHGFILHSQDQDKSRWEMPASLASYAAQDKQAREEWISVLEALFLTPAGLSINDIPPDCSSLLAGFCSLADWLGSWTTTNTFLFNEDAPSDINALRTYFQDRQQDASRVLELSGLVSNKRCYEGVHALLDNGYQPRQLQVLVDALPVAPGLTVIEAPTGSGKTETALAYAWKLIDQQIADSVIFALPTQATANAMLTRMEASASHLFSSPNLILAHGNSRFNHLFQSIKSRAITEQGQEEAWVQCCQWLSQSNKKVFLGQIGVCTIDQVLISVLPVKHRFIRGLGIGRSVLIVDEVHAYDTYMNGLLEAVLKAQADVGGSVILLSATLPMKQKQKLLDTYGLHTDPVENNSAYPLINWRGVNGAQRFDLLAHPEQLPPRFSIQPEPIYLADMLPDLTMLERMIAAANAGAQVCLICNLVDVAQVCYQRLKELNNTQVDIDLFHARFTLNDRREKENRVISDFGKNGERNVGRILVATQVVEQSLDVDFDWLITQHCPADLLFQRLGRLHRHHRKYRPAGFEIPVATILLPDGEGYGRHEHIYSNVRVMWRTQQHIEELNGASLFFPDAYRQWLDSIYDDAEMDEPEWVIKGMDKFESAECEKRFKARKVLQWAEEYSLQDNDETILAVTRDGEMSLPLLPYVQTSSGKQLLDGQVYEDLSYEQQYEALALNRVNVPFTWKRSFSEVVDEDGLLWLEGKQNQDGWFWQGNSIVITYTRDEGMTRVIPANPK
>LR134295.1|VEE27210.1|1011329_1012064_+|phosphoadenosine-phosphosulfate-reductase
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG
>LR134295.1|VEE27208.1|1009543_1011256_+|sulfite-reductase-(NADPH)-hemoprotein-beta-subunit
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPARPLKTGLLEIAKIHKGDFRITANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDLWD
>LR134295.1|VEE27228.1|1022386_1023424_-|alkaline-phosphatase-isozyme-conversion-protein
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKNTPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEVFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRIMLPLVKELAKAS
>LR134295.1|VEE27230.1|1023675_1024584_+|sulfate-adenylyltransferase
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDPKNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>LR134295.1|VEE27232.1|1024585_1026013_+|sulfate-adenylyltransferase
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGIKHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNGIGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGDK
>LR134295.1|VEE27234.1|1026012_1026618_+|adenosine-5-phosphosulfate-kinase
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFTGIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>LR134295.1|VEE27236.1|1026667_1026991_+|putative-cytochrome-oxidase-subunit
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALFMWLLG
>LR134295.1|VEE27238.1|1027184_1027496_+|cell-division-protein
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNNR
>LR134295.1|VEE27240.1|1027514_1028225_+|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>LR134295.1|VEE27242.1|1028224_1028704_+|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>LR134295.1|VEE27244.1|1028700_1029750_+|tRNA-pseudouridine-synthase-D
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADVLAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYFGAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVVRELINTTGDYAHIAE
>LR134295.1|VEE27246.1|1029730_1030492_+|stationary-phase-survival-protein-SurE
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINVPDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW

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Crispr_ID: LR134295_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134295_3

1519552-1519669

Orphan

Consensus_repeat	Method
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134295_3

>merge|LR134295|3|1519552-1519669|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGCTGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAACCGAGCCGTAGGCCGGATAAGGCGTTTACGC

>LR134295|3|3|1519552-1519669|CRISPRCasFinder
CCGAGCCGTAGGCCGGATAAGGCGTTCACGC	TGCATCCGGCACCCGGAGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACAAA
CCGAGCCGTAGGCCGGATAAGGCGTTTACGC

Protein	Signature genes	Signature genes Name	Protein_function
LR134295.1\|VEE28448.1\|1527418_1530046_+\|DNA-gyrase-subunit-A	unknown	unknown	gnl\|CDD\|235502
LR134295.1\|VEE28426.1\|1516945_1517152_-\|yfaH	unknown	unknown	gnl\|CDD\|182050
LR134295.1\|VEE28465.1\|1538695_1539472_+\|DUF2135-family-protein,-function-uncharacterised	unknown	unknown	gnl\|CDD\|227021
LR134295.1\|VEE28423.1\|1515827_1516904_+\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|236859
LR134295.1\|VEE28445.1\|1526549_1527272_-\|3-demethylubiquinone-9-3-methyltransferase	unknown	unknown	gnl\|CDD\|235350
LR134295.1\|VEE28462.1\|1537041_1538691_+\|protein	unknown	unknown	gnl\|CDD\|227732
LR134295.1\|VEE28432.1\|1518070_1518325_-\|putative-ferredoxin	unknown	unknown	gnl\|CDD\|182668
LR134295.1\|VEE28408.1\|1509035_1509935_-\|putative-transposase	unknown	unknown	gnl\|CDD\|182167
LR134295.1\|VEE28417.1\|1512563_1514192_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	unknown	unknown	gnl\|CDD\|236847
LR134295.1\|VEE28414.1\|1511314_1512574_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-B	unknown	unknown	gnl\|CDD\|225617
LR134295.1\|VEE28411.1\|1510127_1511318_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	unknown	unknown	gnl\|CDD\|132422
LR134295.1\|VEE28429.1\|1517366_1518017_+\|pH-inducible-protein-involved-in-stress-response-(putative-kinase)	unknown	unknown	gnl\|CDD\|182136
LR134295.1\|VEE28453.1\|1530194_1531883_+\|putative-membrane-protein-YfaA	unknown	unknown	gnl\|CDD\|227030
LR134295.1\|VEE28456.1\|1531879_1532503_+\|protein	unknown	unknown	gnl\|CDD\|225774
LR134295.1\|VEE28420.1\|1514464_1515823_+\|glycerol-3-phosphate-transporter	unknown	unknown	gnl\|CDD\|236889
LR134295.1\|VEE28435.1\|1518324_1519455_-\|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|181647
LR134295.1\|VEE28459.1\|1532646_1537041_+\|large-extracellular-alpha-helical-protein	unknown	unknown	gnl\|CDD\|225248
LR134295.1\|VEE28438.1\|1519688_1521974_-\|ribonucleoside-diphosphate-reductase	unknown	unknown	gnl\|CDD\|181649
LR134295.1\|VEE28442.1\|1522669_1526422_+\|adhesin	unknown	unknown	gnl\|CDD\|182059
LR134295.1\|VEE28468.1\|1539545_1540730_-\|acetyl-CoA-acetyltransferase	unknown	unknown	gnl\|CDD\|180261

Protein	Function_ID	Function_description	E-value
LR134295.1\|VEE28448.1\|1527418_1530046_+\|DNA-gyrase-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
LR134295.1\|VEE28426.1\|1516945_1517152_-\|yfaH	gnl\|CDD\|182050	PRK09729, PRK09729, hypothetical protein; Provisional.	1.13329e-36
LR134295.1\|VEE28465.1\|1538695_1539472_+\|DUF2135-family-protein,-function-uncharacterised	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	4.17009e-153
LR134295.1\|VEE28423.1\|1515827_1516904_+\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
LR134295.1\|VEE28445.1\|1526549_1527272_-\|3-demethylubiquinone-9-3-methyltransferase	gnl\|CDD\|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	1.58484e-171
LR134295.1\|VEE28462.1\|1537041_1538691_+\|protein	gnl\|CDD\|227732	COG5445, COG5445, Predicted secreted protein [Function unknown].	3.75964e-127
LR134295.1\|VEE28432.1\|1518070_1518325_-\|putative-ferredoxin	gnl\|CDD\|182668	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein.	2.72138e-53
LR134295.1\|VEE28408.1\|1509035_1509935_-\|putative-transposase	gnl\|CDD\|182167	PRK09956, PRK09956, ISNCY family transposase.	0
LR134295.1\|VEE28417.1\|1512563_1514192_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	gnl\|CDD\|236847	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A.	0
LR134295.1\|VEE28414.1\|1511314_1512574_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-B	gnl\|CDD\|225617	COG3075, GlpB, Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism].	0
LR134295.1\|VEE28411.1\|1510127_1511318_-\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	gnl\|CDD\|132422	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit. Members of this protein family are the membrane-anchoring, non-catalytic C subunit, product of the glpC gene, of a three-subunit, FAD-dependent, anaerobic glycerol-3-phosphate dehydrogenase. GlpC lasks classical hydrophobic transmembrane helices; Cole, et al suggest interaction with the membrane may involve amphipathic helices. GlcC has conserved Cys-containing motifs suggestive of iron-sulfur binding. This complex is found mostly in Escherichia coli and closely related species. [Energy metabolism, Anaerobic].	0
LR134295.1\|VEE28429.1\|1517366_1518017_+\|pH-inducible-protein-involved-in-stress-response-(putative-kinase)	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	2.86156e-158
LR134295.1\|VEE28453.1\|1530194_1531883_+\|putative-membrane-protein-YfaA	gnl\|CDD\|227030	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown].	0
LR134295.1\|VEE28456.1\|1531879_1532503_+\|protein	gnl\|CDD\|225774	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown].	3.71745e-140
LR134295.1\|VEE28420.1\|1514464_1515823_+\|glycerol-3-phosphate-transporter	gnl\|CDD\|236889	PRK11273, glpT, glycerol-3-phosphate transporter.	0
LR134295.1\|VEE28435.1\|1518324_1519455_-\|ribonucleotide-diphosphate-reductase-subunit-beta	gnl\|CDD\|181647	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed.	0
LR134295.1\|VEE28459.1\|1532646_1537041_+\|large-extracellular-alpha-helical-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
LR134295.1\|VEE28438.1\|1519688_1521974_-\|ribonucleoside-diphosphate-reductase	gnl\|CDD\|181649	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha.	0
LR134295.1\|VEE28442.1\|1522669_1526422_+\|adhesin	gnl\|CDD\|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	0
LR134295.1\|VEE28468.1\|1539545_1540730_-\|acetyl-CoA-acetyltransferase	gnl\|CDD\|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0

>LR134295.1|VEE28435.1|1518324_1519455_-|ribonucleotide-diphosphate-reductase-subunit-beta
MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKNWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL
>LR134295.1|VEE28432.1|1518070_1518325_-|putative-ferredoxin
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM
>LR134295.1|VEE28429.1|1517366_1518017_+|pH-inducible-protein-involved-in-stress-response-(putative-kinase)
MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIYVKTEGNAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>LR134295.1|VEE28426.1|1516945_1517152_-|yfaH
MNFIRQGLGIALQPELTLKSIAGELCSVPLEPTFYRQISLLAKEKPVEGSPLFLLQMCMEQLVAIGKI
>LR134295.1|VEE28423.1|1515827_1516904_+|glycerophosphodiester-phosphodiesterase
MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLPEHTLPAKAMAYAQGADYLEQDLVMTKDDNLVVLHDHYLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNHSTGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDALYNKAGVNGLFTDFPDKAVKFLNKE
>LR134295.1|VEE28420.1|1514464_1515823_+|glycerol-3-phosphate-transporter
MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRNGG
>LR134295.1|VEE28417.1|1512563_1514192_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
>LR134295.1|VEE28414.1|1511314_1512574_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-B
MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQPVADIHSGLESLRQQAPAHPYSLLGPQRVLDLACQAQALIAESGAQLQGSVELAHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLRELDLSVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVHQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIAQGCGGGVCAVSALHAAQQIAQRAGGQQ
>LR134295.1|VEE28411.1|1510127_1511318_-|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSIAAQQAQYKDQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
>LR134295.1|VEE28408.1|1509035_1509935_-|putative-transposase
MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQTLRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAAMQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDITIVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQCGDTSRFTRFIEEIAERSPLQKERLMTIAERLRQEGHQIGWQEGMHEQAIKIALRMLEQGFEREIVLATTQLTDADIPNCH
>LR134295.1|VEE28438.1|1519688_1521974_-|ribonucleoside-diphosphate-reductase
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINNLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDTIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>LR134295.1|VEE28442.1|1522669_1526422_+|adhesin
MRIIFLRKEYLSLLPSMIASLFSANGVAAVTDSCQGYDVKASCQASRQSLSGITQDWSIADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFANNTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNAMFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIVNNTAFTNNTAEGYGGAIYTNSVTAPYLIDISVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDQYQNQAELNVGSTQQTFVHALTGFQNGTLNIDAGGNVTVNQGSFAGIIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDDGAVLSLEGDAADLTALQDDPQSIVLNGGVLDLSDFSTWQSGTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANNNSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITSDVDTRSDAAGHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLKGDVADILPYASSLWVGDGATFVTGADQDIQSIDAISSGTIDISDGTVLRLTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVTPPSPPEPDPTPDPDPTPDPDPTPDPAPVPVYQPVLNAKVGGYLNNLRAANQAFMMERRDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSDNQGDSRSNMTGTRADNQNHGYAVGLTSSWFQHGNQKQGAWLDSWLQYAWFSNDVSEQEDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDSSTISDDAVKQRGEIKVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW
>LR134295.1|VEE28445.1|1526549_1527272_-|3-demethylubiquinone-9-3-methyltransferase
MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
>LR134295.1|VEE28448.1|1527418_1530046_+|DNA-gyrase-subunit-A
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATAHGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>LR134295.1|VEE28453.1|1530194_1531883_+|putative-membrane-protein-YfaA
MSGEKKAEGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAATSDSQLSKTEISSIKINSETVPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFKDDQQDTEATAIAGDLLSGKKRWQASFGLEERAAEKTPVRQRIVVSARLLGFGYQRLMPSFAGVRFEMGNDGWHSFVALNDESASVDTSFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPISQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQTLNKNRPAMVDVIPTDGIVPLYINPQGVAKLLRNETLTSLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL
>LR134295.1|VEE28456.1|1531879_1532503_+|protein
MRHGLLALICWLCCVVAHSEMLNVEQAGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGLSNQYLPPEMTLTPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYHTGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR
>LR134295.1|VEE28459.1|1532646_1537041_+|large-extracellular-alpha-helical-protein
MRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIIKPSRYVQNNQFSPLKKYPLVEQFRYPLWQTKPVEPQQGVKLEGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYRETTVVFVSDTVALSKVSGNELLVWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVDVTLDARNGGQGSFRLPENAVAGGYELRLAYRNQVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDASGHVTLNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELPSGGKSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGSTAHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQAIGVTQQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDTRDINDSLILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQTAAILSGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEDWRWVGQGVPDILSFGDELSPQNVQVRWREPAKMAQQSNIPVTVERQLYRLIPGEEEMSFILQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQLLEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK
>LR134295.1|VEE28462.1|1537041_1538691_+|protein
MNWRRIVWLLALVTLPTLAEETPLQLVLRGAQHDQLYQLSSSGVTKVSALPDSLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRDTALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLATLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTDGTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKSTTAVNPGVLNGRYRVTFTNGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDREAKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTGARTMTAWTQDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRSTCQLLPKAKAWLAKKMPQWRRILQAETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRNFFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD
>LR134295.1|VEE28465.1|1538695_1539472_+|DUF2135-family-protein,-function-uncharacterised
MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASFSQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSFARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHVVTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPIHGRYQVYINYYGGRSETELTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW
>LR134295.1|VEE28468.1|1539545_1540730_-|acetyl-CoA-acetyltransferase
MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKIDSQHVDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKADSTTEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERLN

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Crispr_ID: LR134295_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134295_4

2186020-2186143

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134295_4

>merge|LR134295|4|2186020-2186143|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>LR134295|4|4|2186020-2186143|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
LR134295.1\|VEE30247.1\|2175473_2176886_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|181699
LR134295.1\|VEE30265.1\|2182236_2183022_+\|putative-oxidoreductase,-cytochrome-b-subunit	unknown	unknown	gnl\|CDD\|184968
LR134295.1\|VEE30244.1\|2174926_2175163_-\|murein-lipoprotein	unknown	unknown	gnl\|CDD\|185294
LR134295.1\|VEE30296.1\|2195294_2196464_+\|major-facilitator-superfamily-protein	unknown	unknown	gnl\|CDD\|225371
LR134295.1\|VEE30293.1\|2193715_2194741_-\|purine-nucleotide-synthesis-repressor	unknown	unknown	gnl\|CDD\|236739
LR134295.1\|VEE30250.1\|2177442_2177652_+\|protein	unknown	unknown	gnl\|CDD\|182359
LR134295.1\|VEE30256.1\|2178754_2180857_+\|putative-aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
LR134295.1\|VEE30290.1\|2192786_2193719_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
LR134295.1\|VEE30299.1\|2196698_2197280_-\|superoxide-dismutase	unknown	unknown	gnl\|CDD\|182534
LR134295.1\|VEE30259.1\|2180869_2181508_+\|putative-oxidoreductase-subunit	unknown	unknown	gnl\|CDD\|182160
LR134295.1\|VEE30287.1\|2191462_2192674_-\|major-facilitator-superfamily-protein	unknown	unknown	gnl\|CDD\|182924
LR134295.1\|VEE30271.1\|2183849_2185454_-\|conserved-protein-with-FAD/NAD(P)-binding-domain	unknown	unknown	gnl\|CDD\|182134
LR134295.1\|VEE30280.1\|2189342_2189984_+\|riboflavin-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183846
LR134295.1\|VEE30262.1\|2181571_2182240_+\|putative-oxidoreductase-Fe-S-subunit	unknown	unknown	gnl\|CDD\|274451
LR134295.1\|VEE30277.1\|2187754_2189128_-\|multidrug-resistance-protein	unknown	unknown	gnl\|CDD\|234981
LR134295.1\|VEE30274.1\|2186457_2187714_+\|Fluffing-protein	unknown	unknown	gnl\|CDD\|137602
LR134295.1\|VEE30284.1\|2190023_2191172_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
LR134295.1\|VEE30268.1\|2183073_2183838_+\|putative-oxidoreductase-subunit	unknown	unknown	gnl\|CDD\|182159
LR134295.1\|VEE30302.1\|2197407_2198223_-\|putative-exported-hydrolase	unknown	unknown	gnl\|CDD\|366353
LR134295.1\|VEE30253.1\|2178107_2178734_+\|putative-oxidoreductase-Fe-S-subunit	unknown	unknown	gnl\|CDD\|182135

Protein	Function_ID	Function_description	E-value
LR134295.1\|VEE30247.1\|2175473_2176886_-\|pyruvate-kinase	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0
LR134295.1\|VEE30265.1\|2182236_2183022_+\|putative-oxidoreductase,-cytochrome-b-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	1.01591e-161
LR134295.1\|VEE30244.1\|2174926_2175163_-\|murein-lipoprotein	gnl\|CDD\|185294	PRK15396, PRK15396, major outer membrane lipoprotein.	2.83509e-37
LR134295.1\|VEE30296.1\|2195294_2196464_+\|major-facilitator-superfamily-protein	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.92383e-98
LR134295.1\|VEE30293.1\|2193715_2194741_-\|purine-nucleotide-synthesis-repressor	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
LR134295.1\|VEE30250.1\|2177442_2177652_+\|protein	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
LR134295.1\|VEE30256.1\|2178754_2180857_+\|putative-aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
LR134295.1\|VEE30290.1\|2192786_2193719_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
LR134295.1\|VEE30299.1\|2196698_2197280_-\|superoxide-dismutase	gnl\|CDD\|182534	PRK10543, PRK10543, superoxide dismutase [Fe].	3.77321e-138
LR134295.1\|VEE30259.1\|2180869_2181508_+\|putative-oxidoreductase-subunit	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	1.93584e-120
LR134295.1\|VEE30287.1\|2191462_2192674_-\|major-facilitator-superfamily-protein	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
LR134295.1\|VEE30271.1\|2183849_2185454_-\|conserved-protein-with-FAD/NAD(P)-binding-domain	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
LR134295.1\|VEE30280.1\|2189342_2189984_+\|riboflavin-synthase-subunit-alpha	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
LR134295.1\|VEE30262.1\|2181571_2182240_+\|putative-oxidoreductase-Fe-S-subunit	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	7.32003e-76
LR134295.1\|VEE30277.1\|2187754_2189128_-\|multidrug-resistance-protein	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
LR134295.1\|VEE30274.1\|2186457_2187714_+\|Fluffing-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
LR134295.1\|VEE30284.1\|2190023_2191172_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
LR134295.1\|VEE30268.1\|2183073_2183838_+\|putative-oxidoreductase-subunit	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	1.54387e-163
LR134295.1\|VEE30302.1\|2197407_2198223_-\|putative-exported-hydrolase	gnl\|CDD\|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	8.51153e-47
LR134295.1\|VEE30253.1\|2178107_2178734_+\|putative-oxidoreductase-Fe-S-subunit	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	6.99609e-140

>LR134295.1|VEE30271.1|2183849_2185454_-|conserved-protein-with-FAD/NAD(P)-binding-domain
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPIYCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARKQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFHRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFHGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>LR134295.1|VEE30268.1|2183073_2183838_+|putative-oxidoreductase-subunit
MYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALVYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC
>LR134295.1|VEE30265.1|2182236_2183022_+|putative-oxidoreductase,-cytochrome-b-subunit
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSATDHGEKVYLYSKAVRLWHWSNALLFVLLLASGLINHFAMVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGDNGHHYRIRRQGWLERAAKQTRFYLFGIMQGEEHPLPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>LR134295.1|VEE30262.1|2181571_2182240_+|putative-oxidoreductase-Fe-S-subunit
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQDNKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>LR134295.1|VEE30259.1|2180869_2181508_+|putative-oxidoreductase-subunit
MNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>LR134295.1|VEE30256.1|2178754_2180857_+|putative-aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRVTTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIHWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPV
>LR134295.1|VEE30253.1|2178107_2178734_+|putative-oxidoreductase-Fe-S-subunit
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>LR134295.1|VEE30250.1|2177442_2177652_+|protein
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>LR134295.1|VEE30247.1|2175473_2176886_-|pyruvate-kinase
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>LR134295.1|VEE30244.1|2174926_2175163_-|murein-lipoprotein
MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQLSNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK
>LR134295.1|VEE30274.1|2186457_2187714_+|Fluffing-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGTGWLKVATGGIVKCTQYGNNGTLSVSDGAIATDVVQSEGGAISLSTLATVNGRHPEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGAELQQSTITVQQGGVLILDGSTVKGDSVTFIVGNINLNGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIRVEITDASRQTLCNALKLQPDEDGIGATLQPA
>LR134295.1|VEE30277.1|2187754_2189128_-|multidrug-resistance-protein
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRASR
>LR134295.1|VEE30280.1|2189342_2189984_+|riboflavin-synthase-subunit-alpha
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>LR134295.1|VEE30284.1|2190023_2191172_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>LR134295.1|VEE30287.1|2191462_2192674_-|major-facilitator-superfamily-protein
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
>LR134295.1|VEE30290.1|2192786_2193719_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRLVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>LR134295.1|VEE30293.1|2193715_2194741_-|purine-nucleotide-synthesis-repressor
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>LR134295.1|VEE30296.1|2195294_2196464_+|major-facilitator-superfamily-protein
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>LR134295.1|VEE30299.1|2196698_2197280_-|superoxide-dismutase
MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIKGTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFGSFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWEHAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA
>LR134295.1|VEE30302.1|2197407_2198223_-|putative-exported-hydrolase
MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKADKKKSTATTKKPQKTAKKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNKTASASFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPYRWGGSSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRTQGRGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR

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Crispr_ID: LR134295_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134295_7

3166238-3166382

Orphan

Consensus_repeat	Method
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134295_7

>merge|LR134295|7|3166238-3166382|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGCTGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTCGTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

>LR134295|7|6|3166238-3166382|CRISPRCasFinder
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGGATGC	TGCGAAAATGCCTTATCTGGCCTACAGATTCGATGCGATTC
GTAGGTCGGATAAGATGCGCAAGCATCGCATCCGACAATAAGTGCCGAATGC

Protein	Signature genes	Signature genes Name	Protein_function
LR134295.1\|VEE32782.1\|3161421_3161613_+\|phage-protein	unknown	unknown	gnl\|CDD\|369224
LR134295.1\|VEE32802.1\|3171594_3172548_+\|DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176131
LR134295.1\|VEE32778.1\|3160589_3161270_+\|exonuclease	unknown	unknown	gnl\|CDD\|378216
LR134295.1\|VEE32808.1\|3174557_3175616_-\|molybdenum-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|182993
LR134295.1\|VEE32788.1\|3162435_3162585_-\|putative-transmembrane-protein	unknown	unknown	unknown
LR134295.1\|VEE32776.1\|3159807_3160593_+\|bacteriophage-recombination-protein	unknown	unknown	gnl\|CDD\|273871
LR134295.1\|VEE32814.1\|3177246_3177396_-\|outer-membrane-or-exported-protein	unknown	unknown	gnl\|CDD\|371231
LR134295.1\|VEE32790.1\|3163280_3163448_+\|Uncharacterised-protein	unknown	unknown	unknown
LR134295.1\|VEE32796.1\|3166405_3168667_-\|putative-aconitase	unknown	unknown	gnl\|CDD\|183125
LR134295.1\|VEE32786.1\|3162003_3162225_+\|putative-C4-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|222775
LR134295.1\|VEE32784.1\|3161689_3161905_+\|ybl17	unknown	unknown	unknown
LR134295.1\|VEE32810.1\|3175618_3176308_-\|molybdenum-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|181841
LR134295.1\|VEE32812.1\|3176307_3177081_-\|molybdate-transporter-periplasmic-protein	unknown	unknown	gnl\|CDD\|182641
LR134295.1\|VEE32780.1\|3161266_3161449_+\|phage-protein	unknown	unknown	gnl\|CDD\|284449
LR134295.1\|VEE32800.1\|3170358_3171411_-\|3-methylitaconate-isomerase	unknown	unknown	gnl\|CDD\|380230
LR134295.1\|VEE32792.1\|3163683_3164754_+\|putative-integrase	unknown	unknown	gnl\|CDD\|271181
LR134295.1\|VEE32798.1\|3168849_3170283_-\|putative-Sodium:sulfate-symporter	unknown	unknown	gnl\|CDD\|279307
LR134295.1\|VEE32804.1\|3172588_3173584_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|182912
LR134295.1\|VEE32794.1\|3164888_3166172_+\|acyl-CoA-thioester-hydrolase	unknown	unknown	gnl\|CDD\|236709
LR134295.1\|VEE32806.1\|3173738_3174557_+\|Phosphotransferase	unknown	unknown	gnl\|CDD\|182523

Protein	Function_ID	Function_description	E-value
LR134295.1\|VEE32782.1\|3161421_3161613_+\|phage-protein	gnl\|CDD\|369224	pfam07131, DUF1382, Protein of unknown function (DUF1382). This family consists of several hypothetical Escherichia coli and bacteriophage lambda-like proteins of around 60 residues in length. The function of this family is unknown. Structural modelling suggests this domain may bind nucleic acids.	7.90907e-23
LR134295.1\|VEE32802.1\|3171594_3172548_+\|DNA-binding-transcriptional-regulator	gnl\|CDD\|176131	cd08440, PBP2_LTTR_like_4, TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.09679e-82
LR134295.1\|VEE32806.1\|3173738_3174557_+\|Phosphotransferase	gnl\|CDD\|182523	PRK10530, PRK10530, pyridoxal phosphate (PLP) phosphatase; Provisional.	0
LR134295.1\|VEE32808.1\|3174557_3175616_-\|molybdenum-ABC-transporter-ATP-binding-protein	gnl\|CDD\|182993	PRK11144, modC, molybdenum ABC transporter ATP-binding protein ModC.	0
LR134295.1\|VEE32776.1\|3159807_3160593_+\|bacteriophage-recombination-protein	gnl\|CDD\|273871	TIGR01913, Uncharacterized_protein_UU154, phage recombination protein Bet. This model represents the phage recombination protein Bet from a number of phage, including phage lambda. All members of this family are found in phage genomes or in putative prophage regions of bacterial genomes. [Mobile and extrachromosomal element functions, Prophage functions].	1.45393e-64
LR134295.1\|VEE32778.1\|3160589_3161270_+\|exonuclease	gnl\|CDD\|378216	pfam09588, YqaJ, YqaJ-like viral recombinase domain. This protein family is found in many different bacterial species but is of viral origin. The protein forms an oligomer and functions as a processive alkaline exonuclease that digests linear double-stranded DNA in a Mg(2+)-dependent reaction, It has a preference for 5'-phosphorylated DNA ends. It thus forms part of the two-component SynExo viral recombinase functional unit.	3.97391e-29
LR134295.1\|VEE32786.1\|3162003_3162225_+\|putative-C4-type-zinc-finger-protein	gnl\|CDD\|222775	PHA00080, PHA00080, DksA-like zinc finger domain containing protein.	1.57279e-26
LR134295.1\|VEE32796.1\|3166405_3168667_-\|putative-aconitase	gnl\|CDD\|183125	PRK11413, PRK11413, putative hydratase; Provisional.	0
LR134295.1\|VEE32810.1\|3175618_3176308_-\|molybdenum-ABC-transporter-permease	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	2.41762e-146
LR134295.1\|VEE32812.1\|3176307_3177081_-\|molybdate-transporter-periplasmic-protein	gnl\|CDD\|182641	PRK10677, modA, molybdate transporter periplasmic protein; Provisional.	0
LR134295.1\|VEE32780.1\|3161266_3161449_+\|phage-protein	gnl\|CDD\|284449	pfam07026, DUF1317, Protein of unknown function (DUF1317). This family consists of several hypothetical bacterial and phage proteins of around 60 residues in length. The function of this family is unknown.	4.99888e-34
LR134295.1\|VEE32800.1\|3170358_3171411_-\|3-methylitaconate-isomerase	gnl\|CDD\|380230	NF033377, OMA_tautomer, 4-oxalomesaconate tautomerase.	0
LR134295.1\|VEE32792.1\|3163683_3164754_+\|putative-integrase	gnl\|CDD\|271181	cd00800, INT_Lambda_C, C-terminal catalytic domain of Lambda integrase, a tyrosine-based site-specific recombinase. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome. They are tyrosine-based site-specific recombinase and belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The phage lambda integrase can bridge two different and well-separated DNA sequences called arm- and core-sites. The C-terminal domain binds, cleaves and re-ligates DNA strands at the core-sites, while the N-terminal domain is largely responsible for high-affinity binding to the arm-type sites.	4.69412e-62
LR134295.1\|VEE32798.1\|3168849_3170283_-\|putative-Sodium:sulfate-symporter	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	0
LR134295.1\|VEE32804.1\|3172588_3173584_-\|6-phosphogluconolactonase	gnl\|CDD\|182912	PRK11028, PRK11028, 6-phosphogluconolactonase; Provisional.	0
LR134295.1\|VEE32794.1\|3164888_3166172_+\|acyl-CoA-thioester-hydrolase	gnl\|CDD\|236709	PRK10531, PRK10531, putative acyl-CoA thioester hydrolase.	0
LR134295.1\|VEE32814.1\|3177246_3177396_-\|outer-membrane-or-exported-protein	gnl\|CDD\|371231	pfam10766, AcrZ, Multidrug efflux pump-associated protein AcrZ. AcrZ is associated with the AcrA-TolC multidrug efflux pump, it may enhance the ability of the pump to recognize and export certain substrates.	1.04381e-17

>LR134295.1|VEE32794.1|3164888_3166172_+|acyl-CoA-thioester-hydrolase
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPADWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFNAFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVDDNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK
>LR134295.1|VEE32792.1|3163683_3164754_+|putative-integrase
MGRRRSHERRDLPPNLYIRNNGYYCYRDPRTGKEFGLGRDRRIAITEAIQANIELFSGHKHKPLTARINSDNSVTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRRGLPDAPLEDITTKEIAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAEGHITTNPVAATRAAKSEVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVTGQRVGDLCEMKWSDIVDGYLYVEQSKTGVKIAIPTTLHVDALGISMKETLDKCKEILGGETIIASTRREPLSSGTVSRYFMRARKASGLSFEGDPPTFHELRSLSARLYEKQISDKFAQHLLGHKSDTMASQYRDDRGREWDKIEIK
>LR134295.1|VEE32790.1|3163280_3163448_+|Uncharacterised-protein
MHFRVTGEWNGEPFNRVIEAENISDCYDHWMLWAQIAHADVTNIRIEELKEHQAA
>LR134295.1|VEE32788.1|3162435_3162585_-|putative-transmembrane-protein
MDDPDLHENIRICYPYGNYEYDNIIYVEKKINILGAVVTYAQTARDDTE
>LR134295.1|VEE32786.1|3162003_3162225_+|putative-C4-type-zinc-finger-protein
MADIIDSASEIEELQRNTAIKMRRLNHQAISATHCCECGDPIDERRRLVVQGCRTCASCQEDLELISKQRGSK
>LR134295.1|VEE32784.1|3161689_3161905_+|ybl17
MTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHRETVTLMGFTPTHLSLAIGMLNGVFKER
>LR134295.1|VEE32782.1|3161421_3161613_+|phage-protein
MHKASPVELRTSIEMAHSLAQIGVRFVPIPVETDEEFHTLAASLSQKLEMMVAKAEADERDQV
>LR134295.1|VEE32780.1|3161266_3161449_+|phage-protein
MKHPHDNIRVGTITFVYSVTKRGWVFPGLSVIRNPLKAQRLAEEINNKRGAVCTKHLPLS
>LR134295.1|VEE32778.1|3160589_3161270_+|exonuclease
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVIESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQYSMWVTRKDAWYFANYDPRMKREGLHYVVIERNEKYIASFDEMVPEFIEKMDEALAEIGFVFGEQWR
>LR134295.1|VEE32776.1|3159807_3160593_+|bacteriophage-recombination-protein
MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQFIALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNESCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCARLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDDDLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKATEQKVAA
>LR134295.1|VEE32796.1|3166405_3168667_-|putative-aconitase
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTMAVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVAALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQGFVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRSNPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMAEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>LR134295.1|VEE32798.1|3168849_3170283_-|putative-Sodium:sulfate-symporter
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSVAVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNMLIGWNML
>LR134295.1|VEE32800.1|3170358_3171411_-|3-methylitaconate-isomerase
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVALTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRASVIRTTRKIFSGEVYLP
>LR134295.1|VEE32802.1|3171594_3172548_+|DNA-binding-transcriptional-regulator
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFTPLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>LR134295.1|VEE32804.1|3172588_3173584_-|6-phosphogluconolactonase
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDGHLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH
>LR134295.1|VEE32806.1|3173738_3174557_+|Phosphotransferase
MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVIKALQLIEMLNEHHIHGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>LR134295.1|VEE32808.1|3174557_3175616_-|molybdenum-ABC-transporter-ATP-binding-protein
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKDICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMSKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLDIPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELAIKPGLWLYAQIKSVSITA
>LR134295.1|VEE32810.1|3175618_3176308_-|molybdenum-ABC-transporter-permease
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARSLGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>LR134295.1|VEE32812.1|3176307_3177081_-|molybdate-transporter-periplasmic-protein
MARKWLNLFAGAALSFAVAGNTLADEGKITVFAAASLTNAMQDIATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTASRQTLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKLGAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKVEYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTIK
>LR134295.1|VEE32814.1|3177246_3177396_-|outer-membrane-or-exported-protein
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH

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Crispr_ID: LR134295_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LR134295_8

3402302-3402398

Orphan

Consensus_repeat	Method
TTGTAGGCCTGATAAGATGCGTCAAGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of LR134295_8

>merge|LR134295|8|3402302-3402398|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGCATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGGTTGTAGGCCTGATAAGACGCGTCAAGC

>LR134295|8|7|3402302-3402398|CRISPRCasFinder
TTGTAGGCCTGATAAGATGCGTCAAGC	ATCGCATCAGGCATTGTGCACCAATTGCCGGATGCGGCACCGG
TTGTAGGCCTGATAAGACGCGTCAAGC

Protein	Signature genes	Signature genes Name	Protein_function
LR134295.1\|VEE33229.1\|3410730_3411876_-\|glycerate-kinase-II	unknown	unknown	gnl\|CDD\|182152
LR134295.1\|VEE33234.1\|3413255_3414617_-\|allantoinase	unknown	unknown	gnl\|CDD\|169193
LR134295.1\|VEE33200.1\|3396890_3397103_+\|putative-RNA-binding-protein	unknown	unknown	gnl\|CDD\|183166
LR134295.1\|VEE33216.1\|3403321_3404137_-\|putative-carboxylase	unknown	unknown	gnl\|CDD\|378658
LR134295.1\|VEE33220.1\|3405416_3407084_-\|FdrA-protein	unknown	unknown	gnl\|CDD\|180395
LR134295.1\|VEE33206.1\|3399326_3399821_+\|peptidyl-prolyl-cis-trans-isomerase-B	unknown	unknown	gnl\|CDD\|182734
LR134295.1\|VEE33198.1\|3396022_3396889_+\|5,10-methylene-tetrahydrofolate-dehydrogenase	unknown	unknown	gnl\|CDD\|236760
LR134295.1\|VEE33210.1\|3400663_3401173_+\|phosphoribosylaminoimidazole-carboxylase-catalytic-subunit	unknown	unknown	gnl\|CDD\|223119
LR134295.1\|VEE33208.1\|3399823_3400546_+\|UDP-2,3-diacylglucosamine-hydrolase	unknown	unknown	gnl\|CDD\|235420
LR134295.1\|VEE33196.1\|3395009_3395552_-\|fimbrial-like-protein	unknown	unknown	gnl\|CDD\|237920
LR134295.1\|VEE33218.1\|3404147_3405407_-\|putative-cytoplasmic-protein	unknown	unknown	gnl\|CDD\|377673
LR134295.1\|VEE33194.1\|3394097_3394790_-\|fimbrial-chaperone	unknown	unknown	gnl\|CDD\|185117
LR134295.1\|VEE33224.1\|3408471_3409707_+\|allantoate-amidohydrolase	unknown	unknown	gnl\|CDD\|274471
LR134295.1\|VEE33214.1\|3402431_3403325_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|181831
LR134295.1\|VEE33212.1\|3401169_3402237_+\|phosphoribosylaminoimidazole-carboxylase-ATPase-subunit	unknown	unknown	gnl\|CDD\|235674
LR134295.1\|VEE33226.1\|3409717_3410503_+\|putative-glyoxylate-utilization	unknown	unknown	gnl\|CDD\|200251
LR134295.1\|VEE33204.1\|3397767_3399153_-\|cysteinyl-tRNA-synthetase	unknown	unknown	gnl\|CDD\|234705
LR134295.1\|VEE33231.1\|3411897_3413199_-\|putative-permease	unknown	unknown	gnl\|CDD\|183124
LR134295.1\|VEE33222.1\|3407400_3408450_+\|ureidoglycolate-dehydrogenase	unknown	unknown	gnl\|CDD\|184985
LR134295.1\|VEE33202.1\|3397210_3397732_+\|putative-membrane-bound-metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|224899

Protein	Function_ID	Function_description	E-value
LR134295.1\|VEE33229.1\|3410730_3411876_-\|glycerate-kinase-II	gnl\|CDD\|182152	PRK09932, PRK09932, glycerate 3-kinase.	0
LR134295.1\|VEE33234.1\|3413255_3414617_-\|allantoinase	gnl\|CDD\|169193	PRK08044, PRK08044, allantoinase AllB.	0
LR134295.1\|VEE33200.1\|3396890_3397103_+\|putative-RNA-binding-protein	gnl\|CDD\|183166	PRK11507, PRK11507, ribosome-associated protein YbcJ.	1.38756e-42
LR134295.1\|VEE33216.1\|3403321_3404137_-\|putative-carboxylase	gnl\|CDD\|378658	pfam11392, DUF2877, Protein of unknown function (DUF2877). This bacterial family of proteins are putative carboxylase proteins however this cannot be confirmed.	2.28312e-37
LR134295.1\|VEE33220.1\|3405416_3407084_-\|FdrA-protein	gnl\|CDD\|180395	PRK06091, PRK06091, membrane protein FdrA; Validated.	0
LR134295.1\|VEE33206.1\|3399326_3399821_+\|peptidyl-prolyl-cis-trans-isomerase-B	gnl\|CDD\|182734	PRK10791, PRK10791, peptidylprolyl isomerase B.	9.12357e-121
LR134295.1\|VEE33198.1\|3396022_3396889_+\|5,10-methylene-tetrahydrofolate-dehydrogenase	gnl\|CDD\|236760	PRK10792, PRK10792, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
LR134295.1\|VEE33210.1\|3400663_3401173_+\|phosphoribosylaminoimidazole-carboxylase-catalytic-subunit	gnl\|CDD\|223119	COG0041, PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism].	1.14024e-91
LR134295.1\|VEE33208.1\|3399823_3400546_+\|UDP-2,3-diacylglucosamine-hydrolase	gnl\|CDD\|235420	PRK05340, PRK05340, UDP-2,3-diacylglucosamine hydrolase; Provisional.	1.25513e-165
LR134295.1\|VEE33196.1\|3395009_3395552_-\|fimbrial-like-protein	gnl\|CDD\|237920	PRK15194, PRK15194, type 1 fimbrial protein subunit FimA.	9.67411e-92
LR134295.1\|VEE33218.1\|3404147_3405407_-\|putative-cytoplasmic-protein	gnl\|CDD\|377673	pfam06545, DUF1116, Protein of unknown function (DUF1116). This family contains hypothetical bacterial proteins of unknown function.	1.8369e-131
LR134295.1\|VEE33194.1\|3394097_3394790_-\|fimbrial-chaperone	gnl\|CDD\|185117	PRK15195, PRK15195, molecular chaperone FimC.	4.4332e-149
LR134295.1\|VEE33224.1\|3408471_3409707_+\|allantoate-amidohydrolase	gnl\|CDD\|274471	TIGR03176, AllC, allantoate amidohydrolase. This enzyme catalyzes the breakdown of allantoate, first to ureidoglycine by hydrolysis and then decarboxylation of one of the two equivalent ureido groups. Ureidoglycine then spontaneously exchanges ammonia for water resulting in ureidoglycolate. This enzyme is an alternative to allantoicase (3.5.3.4) which releases urea. [Central intermediary metabolism, Nitrogen metabolism].	0
LR134295.1\|VEE33214.1\|3402431_3403325_-\|carbamate-kinase	gnl\|CDD\|181831	PRK09411, PRK09411, carbamate kinase; Reviewed.	0
LR134295.1\|VEE33212.1\|3401169_3402237_+\|phosphoribosylaminoimidazole-carboxylase-ATPase-subunit	gnl\|CDD\|235674	PRK06019, PRK06019, phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed.	5.70382e-179
LR134295.1\|VEE33226.1\|3409717_3410503_+\|putative-glyoxylate-utilization	gnl\|CDD\|200251	TIGR03214, ura-cupin, putative allantoin catabolism protein. This model represents a protein containing a tandem arrangement of cupin domains (N-terminal part of pfam07883 and C-terminal more distantly related to pfam00190). This protein is found in the vicinity of genes involved in the catabolism of allantoin, a breakdown product of urate and sometimes of urate iteslf. The distribution of pathway components in the genomes in which this family is observed suggests that the function is linked to the allantoate catabolism to glyoxylate pathway (GenProp0686) since it is sometimes found in genomes lacking any elements of the xanthine-to-allantoin pathways (e.g. in Enterococcus faecalis).	3.35803e-151
LR134295.1\|VEE33204.1\|3397767_3399153_-\|cysteinyl-tRNA-synthetase	gnl\|CDD\|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
LR134295.1\|VEE33231.1\|3411897_3413199_-\|putative-permease	gnl\|CDD\|183124	PRK11412, PRK11412, uracil/xanthine transporter.	0
LR134295.1\|VEE33222.1\|3407400_3408450_+\|ureidoglycolate-dehydrogenase	gnl\|CDD\|184985	PRK15025, PRK15025, ureidoglycolate dehydrogenase; Provisional.	0
LR134295.1\|VEE33202.1\|3397210_3397732_+\|putative-membrane-bound-metal-dependent-hydrolase	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.17059e-30

>LR134295.1|VEE33212.1|3401169_3402237_+|phosphoribosylaminoimidazole-carboxylase-ATPase-subunit
MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAERSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRADETEQLPAECYGECIVEQGINFSGEVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELGYVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVVNNPSVMINLIGSDANYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEALIPLLPPEYASGVIWAQSKFG
>LR134295.1|VEE33210.1|3400663_3401173_+|phosphoribosylaminoimidazole-carboxylase-catalytic-subunit
MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVDSLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVLENPDPRGAA
>LR134295.1|VEE33208.1|3399823_3400546_+|UDP-2,3-diacylglucosamine-hydrolase
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANSKEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
>LR134295.1|VEE33206.1|3399326_3399821_+|peptidyl-prolyl-cis-trans-isomerase-B
MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRVINGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINVVDNDFLNFSGESLQGWGYCVFAEVVDGMDVVDKIKGVATGRSGMHQDVPKEDVIIESVTVSE
>LR134295.1|VEE33204.1|3397767_3399153_-|cysteinyl-tRNA-synthetase
MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTFVAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDALNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDLDQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLGNHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFTVRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLEDGPQGTTWRRK
>LR134295.1|VEE33202.1|3397210_3397732_+|putative-membrane-bound-metal-dependent-hydrolase
MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLSFNFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLIRCWLFLTVSLLSHSLLDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTAYGHQVIISELMWVWLPGMLLMGMLWWRRR
>LR134295.1|VEE33200.1|3396890_3397103_+|putative-RNA-binding-protein
MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGAVETRKRCKIVAGQTVSFAGHSVQVVA
>LR134295.1|VEE33198.1|3396022_3396889_+|5,10-methylene-tetrahydrofolate-dehydrogenase
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE
>LR134295.1|VEE33196.1|3395009_3395552_-|fimbrial-like-protein
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGTGTSASAGQANADATFIMRYE
>LR134295.1|VEE33194.1|3394097_3394790_-|fimbrial-chaperone
MMTKIKLLMLIIFYLIISASAHAAGGIALGATRIIYPADAKQTAVWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAADRESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSRSGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVNSQIPLPSGVQGKLKFQTVNDYGSVTPVREVNLN
>LR134295.1|VEE33214.1|3402431_3403325_-|carbamate-kinase
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVTTVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQPRKILDSEAIELLLKEGHVVICSGGGGVPVTEDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSGGKPAWIGALSRIEETLAGEAGTCISL
>LR134295.1|VEE33216.1|3403321_3404137_-|putative-carboxylase
MTIIHPLLASRSAPNYRQSWRLAGVWRRAINLMTESGELLTLHRQGSGFGPGGWMLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPPAHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLGKGPGLTPSHDDTLSGMLLAAWYYGALDARSGRQFFACSDNLQLVTTAVSVSYLRYAAQGYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP
>LR134295.1|VEE33218.1|3404147_3405407_-|putative-cytoplasmic-protein
MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLHAGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMGGITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLSAALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEVMDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFTAPVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAARAVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQIGAGTVRAPLACFEQALEALAESMGIG
>LR134295.1|VEE33220.1|3405416_3407084_-|FdrA-protein
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATSNDICVTIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDASLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLKSRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFICGLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADGHQIIDLGDDFYTVGRPHPMIDPTLRNQLITDLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDNQPLYAIATVTGTERDPQCRSQQIATVEDAGIAVVSSLPEATLLAAALIRPLSPATQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ
>LR134295.1|VEE33222.1|3407400_3408450_+|ureidoglycolate-dehydrogenase
MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQQKGVAVVGISRMGHSGAISYFVQQAARAGLIGISMCQSDPMVVPFGGAEIYYGTNPLAFAAPGEGDEVLTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHVVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISDALYNTSYETKNPFAQ
>LR134295.1|VEE33224.1|3408471_3409707_+|allantoate-amidohydrolase
MITHFRQAIEETLPWLSSFGADPAGGMTRLLYSPEWLETQQQFKKRMAASGLETRFDEVGNLYGRLSGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWLAIDWLKTQYGAPLRTLEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNSFVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVYAFSRICHQSFEKAKKMGDPLVLTFGKVEPRPNTVNVVPGKTTFTIDCRHTDAAILRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKDLVATLTELCESEKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITDLAEGVKTLAIMLYQLAWQK
>LR134295.1|VEE33226.1|3409717_3410503_+|putative-glyoxylate-utilization
MGYLNNVTGYRDDLLANRAIVKHGNFALLTPDGLVKNIIPGFENCDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFALSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGHAPWLVSGNASELERIHYEGMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNSWIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI
>LR134295.1|VEE33229.1|3410730_3411876_-|glycerate-kinase-II
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDAHYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGETVNAFYGLTGDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQVLVANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAVNLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN
>LR134295.1|VEE33231.1|3411897_3413199_-|putative-permease
MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATSLAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFGIADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSHSLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTRYRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVPALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMALPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE
>LR134295.1|VEE33234.1|3413255_3414617_-|allantoinase
MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVMDASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVCHVSSPEGVEEVTRARQEGQDVTCESCPHYFVLDTDQFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGGIAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQPNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILKHQQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
LR134295_2	2.8\|1021635\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021635-1021666	32	NZ_CP042584	Escherichia coli strain LD91-1 plasmid pLD91-1-76kb, complete sequence	74762-74793	0	1.0
LR134295_5	5.1\|2854483\|40\|LR134295\|CRISPRCasFinder	2854483-2854522	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	0	1.0
LR134295_6	6.1\|3155204\|24\|LR134295\|PILER-CR	3155204-3155227	24	NC_049946	Escherichia virus Lambda_4A7 genome assembly, chromosome: 1	37652-37675	0	1.0
LR134295_6	6.1\|3155204\|24\|LR134295\|PILER-CR	3155204-3155227	24	LR595861	Escherichia virus Lambda_4C10 genome assembly, chromosome: 1	37935-37958	0	1.0
LR134295_6	6.2\|3155251\|25\|LR134295\|PILER-CR	3155251-3155275	25	NC_049946	Escherichia virus Lambda_4A7 genome assembly, chromosome: 1	37604-37628	0	1.0
LR134295_6	6.2\|3155251\|25\|LR134295\|PILER-CR	3155251-3155275	25	LR595861	Escherichia virus Lambda_4C10 genome assembly, chromosome: 1	37887-37911	0	1.0
LR134295_2	2.19\|1022306\|32\|LR134295\|CRISPRCasFinder,CRT	1022306-1022337	32	LC542972	Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence	246937-246968	1	0.969
LR134295_6	6.1\|3155204\|24\|LR134295\|PILER-CR	3155204-3155227	24	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	44572-44595	1	0.958
LR134295_6	6.2\|3155251\|25\|LR134295\|PILER-CR	3155251-3155275	25	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	44524-44548	1	0.96
LR134295_4	4.1\|2186063\|38\|LR134295\|CRISPRCasFinder	2186063-2186100	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
LR134295_1	1.4\|995447\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995447-995479	33	NZ_LR134258	Klebsiella aerogenes strain NCTC9644 plasmid 5, complete sequence	3574-3606	4	0.879
LR134295_1	1.4\|995447\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995447-995479	33	LR134281	Klebsiella aerogenes strain NCTC9793 genome assembly, plasmid: 6	3567-3599	4	0.879
LR134295_1	1.4\|995447\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995447-995479	33	KY271401	Klebsiella phage 1 LV-2017, complete genome	21043-21075	4	0.879
LR134295_2	2.11\|1021818\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021818-1021849	32	MF547662	Clostridioides phage LIBA6276, complete genome	37369-37400	4	0.875
LR134295_2	2.11\|1021818\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021818-1021849	32	MF547663	Clostridioides phage LIBA2945, complete genome	37369-37400	4	0.875
LR134295_6	6.2\|3155251\|25\|LR134295\|PILER-CR	3155251-3155275	25	NZ_CP015341	Lactobacillus brevis strain 100D8 plasmid unnamed3, complete sequence	35661-35685	4	0.84
LR134295_2	2.8\|1021635\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021635-1021666	32	NC_014108	Enterobacter cloacae subsp. cloacae ATCC 13047 plasmid pECL_B, complete sequence	6021-6052	5	0.844
LR134295_2	2.8\|1021635\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021635-1021666	32	NZ_CP030922	Escherichia coli strain KL53 plasmid pKL53-S, complete sequence	5379-5410	5	0.844
LR134295_2	2.8\|1021635\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021635-1021666	32	NZ_CP038659	Citrobacter freundii strain 680 plasmid p680_1, complete sequence	372822-372853	5	0.844
LR134295_2	2.8\|1021635\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021635-1021666	32	MN699848	Citrobacter pasteurii strain 175G8 plasmid pCfr-OXA-198, complete sequence	37054-37085	5	0.844
LR134295_2	2.11\|1021818\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021818-1021849	32	NZ_CP029155	Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence	83504-83535	5	0.844
LR134295_1	1.4\|995447\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995447-995479	33	KY653119	Morganella phage IME1369_02, complete genome	18216-18248	6	0.818
LR134295_2	2.4\|1021391\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021391-1021422	32	NZ_AP018520	Sphingobium sp. YG1 plasmid pYGP1, complete sequence	43472-43503	6	0.812
LR134295_2	2.12\|1021879\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021879-1021910	32	NZ_CP025114	Bradyrhizobium sp. SK17 strain CBNU plasmid unnamed, complete sequence	241497-241528	6	0.812
LR134295_2	2.12\|1021879\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021879-1021910	32	NZ_CP044544	Bradyrhizobium betae strain PL7HG1 plasmid pBbPL7HG1, complete sequence	137039-137070	6	0.812
LR134295_2	2.19\|1022306\|32\|LR134295\|CRISPRCasFinder,CRT	1022306-1022337	32	MK455769	Aeromonas phage MJG, complete genome	10369-10400	7	0.781
LR134295_2	2.3\|1021330\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021330-1021361	32	NC_018454	Cronobacter phage phiES15, complete genome	8781-8812	8	0.75
LR134295_2	2.3\|1021330\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021330-1021361	32	JQ780327	Cronobacter phage phiES15, complete sequence	8781-8812	8	0.75
LR134295_2	2.17\|1022184\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1022184-1022215	32	NZ_CP013415	Burkholderia ubonensis strain MSMB2035 plasmid pMSMB2035, complete sequence	218852-218883	8	0.75
LR134295_2	2.5\|1021452\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021452-1021483	32	NZ_CP009595	Bacillus cereus strain 3a plasmid pBFC_3, complete sequence	298003-298034	9	0.719
LR134295_2	2.5\|1021452\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021452-1021483	32	NZ_CP009606	Bacillus cereus strain S2-8 plasmid pBFR_2, complete sequence	164238-164269	9	0.719
LR134295_2	2.5\|1021452\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021452-1021483	32	NZ_CP053994	Bacillus cereus strain FDAARGOS_780 plasmid unnamed1, complete sequence	238009-238040	9	0.719
LR134295_2	2.5\|1021452\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021452-1021483	32	NZ_CP053992	Bacillus cereus strain FDAARGOS_781 plasmid unnamed2, complete sequence	221025-221056	9	0.719
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP024236	Escherichia coli O6:H16 strain 2014EL-1346-6 plasmid unnamed4, complete sequence	57083-57114	9	0.719
LR134295_2	2.8\|1021635\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021635-1021666	32	NZ_CP045296	Paenibacillus cellulositrophicus strain KACC 16577 plasmid unnamed1, complete sequence	238917-238948	9	0.719
LR134295_2	2.11\|1021818\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021818-1021849	32	MN693584	Marine virus AFVG_25M163, complete genome	29591-29622	9	0.719
LR134295_2	2.11\|1021818\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021818-1021849	32	MN103543	Pseudomonas phage vB_PaeM_PS119XW, complete genome	258501-258532	9	0.719
LR134295_2	2.11\|1021818\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021818-1021849	32	MK599315	Pseudomonas phage PA1C, complete genome	257887-257918	9	0.719
LR134295_2	2.12\|1021879\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021879-1021910	32	NZ_CP054028	Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence	1548232-1548263	9	0.719
LR134295_2	2.15\|1022062\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1022062-1022093	32	AP014022	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C112A-MedDCM-OCT-S32-C75, * SEQUENCING IN PROGRESS *	22698-22729	9	0.719
LR134295_2	2.15\|1022062\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1022062-1022093	32	AP014023	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C112A-MedDCM-OCT-S35-C64, * SEQUENCING IN PROGRESS *	23700-23731	9	0.719
LR134295_2	2.17\|1022184\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1022184-1022215	32	NZ_CP014797	Salipiger profundus strain JLT2016 plasmid pTPRO1, complete sequence	208455-208486	9	0.719
LR134295_2	2.19\|1022306\|32\|LR134295\|CRISPRCasFinder,CRT	1022306-1022337	32	NC_047954	Pseudomonas phage Njord, complete genome	11435-11466	9	0.719
LR134295_2	2.2\|1021269\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021269-1021300	32	NZ_CP027239	Dietzia sp. oral taxon 368 strain W5195 plasmid unnamed1, complete sequence	55281-55312	10	0.688
LR134295_2	2.4\|1021391\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021391-1021422	32	NZ_CP021914	Sagittula sp. P11 plasmid unnamed1, complete sequence	50199-50230	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_LT904879	Salmonella enterica subsp. enterica serovar Typhi strain ty3-193 genome assembly, plasmid: 2	19612-19643	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_KX129784	Escherichia coli strain H226B plasmid pH226B, complete sequence	115804-115835	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NC_009981	Salmonella enterica subsp. enterica serovar Choleraesuis plasmid pMAK1, complete sequence	116173-116204	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029645	Salmonella enterica subsp. enterica serovar Typhi strain 311189_217186 plasmid pHCM1, complete sequence	182725-182756	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP053721	Escherichia coli strain CP131_Sichuan plasmid pCP131-IncHI1, complete sequence	110105-110136	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP026790	Shigella flexneri 2a strain ATCC 29903 plasmid unnamed2, complete sequence	109122-109153	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP039717	Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS000211 plasmid p10-3184.1, complete sequence	221496-221527	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	KP899804	Salmonella enterica strain F8475 plasmid pF8475, complete sequence	207469-207500	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	KP899805	Salmonella enterica strain 109/9 plasmid p109/9, complete sequence	199664-199695	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP037875	Salmonella enterica subsp. enterica serovar 4,[5],12:i:- strain PNCS015054 plasmid pPNCS015054_S2, complete sequence	13581-13612	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP018652	Salmonella enterica subsp. enterica serovar Enteritidis strain 81-1705 plasmid pSE81-1705-1, complete sequence	73431-73462	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP044299	Escherichia coli strain P59A plasmid pP59A-CTX-M-55, complete sequence	187798-187829	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029690	Escherichia coli strain SD134209 plasmid pSD134209-1, complete sequence	106322-106353	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NC_003384	Salmonella enterica subsp. enterica serovar Typhi str. CT18 plasmid pHCM1, complete sequence	148086-148117	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP049354	Escherichia coli strain T28R plasmid pT28R-1, complete sequence	93116-93147	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	AP020333	Salmonella enterica SESen3709 plasmid pSESen3709_1 DNA, complete genome	185318-185349	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP039559	Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS014846 plasmid p08-4425.1, complete sequence	219648-219679	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP037911	Escherichia coli strain YSP8-1 plasmid pYSP8-1, complete sequence	158306-158337	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP046717	Escherichia coli strain T16R plasmid pT16R-1, complete sequence	93116-93147	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP046007	Escherichia coli strain 1919D62 plasmid p1919D62-1, complete sequence	167798-167829	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NC_002305	Salmonella typhi plasmid R27, complete sequence	128806-128837	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP046004	Escherichia coli strain 1919D3 plasmid p1919D3-1, complete sequence	91681-91712	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029895	Salmonella enterica subsp. enterica serovar Typhi strain 311189_252186 plasmid pHCM1, complete sequence	183046-183077	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029877	Salmonella enterica subsp. enterica serovar Typhi strain 311189_224186 plasmid pHCM1, complete sequence	182844-182875	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP033094	Escherichia coli strain CP53 plasmid pCP53-mcr, complete sequence	37794-37825	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	LT905061	Salmonella enterica subsp. enterica serovar Typhi isolate ISP_03_07467_SGB110-sc-1979083 genome assembly, plasmid: 2	36345-36376	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029926	Salmonella enterica subsp. enterica serovar Typhi strain 311189_218186 plasmid pHCM1, complete sequence	124973-125004	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029947	Salmonella enterica subsp. enterica serovar Typhi strain 311189_210186 plasmid pHCM1, complete sequence	184389-184420	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP044968	Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS007098 plasmid pPNCS014881.1, complete sequence	94449-94480	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP044958	Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS007087 plasmid pPNCS007087.1, complete sequence	26677-26708	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029943	Salmonella enterica subsp. enterica serovar Typhi strain 311189_212186 plasmid pHCM1, complete sequence	182833-182864	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029953	Salmonella enterica subsp. enterica serovar Typhi strain 311189_204186 plasmid pHCM1, complete sequence	183156-183187	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029955	Salmonella enterica subsp. enterica serovar Typhi strain 311189_202186 plasmid pHCM1, complete sequence	183101-183132	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP022495	Salmonella enterica subsp. enterica serovar Derby strain SA20035215 plasmid unnamed1, complete sequence	197454-197485	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP016184	Escherichia coli strain EC2 plasmid pEC2-4, complete sequence	205427-205458	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP016183	Escherichia coli strain EC2_1 plasmid pEC2_1-4, complete sequence	191663-191694	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029924	Salmonella enterica subsp. enterica serovar Typhi strain 311189_221186 plasmid pHCM1, complete sequence	49708-49739	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029934	Salmonella enterica subsp. enterica serovar Typhi strain 311189_214186 plasmid pHCM1, complete sequence	182844-182875	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NC_013365	Escherichia coli O111:H- str. 11128 plasmid pO111_1, complete sequence	126184-126215	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP041449	Escherichia coli strain YPE10 plasmid pYPE10-190k-tetX4, complete sequence	93117-93148	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029939	Salmonella enterica subsp. enterica serovar Typhi strain 311189_206186 plasmid pHCM1, complete sequence	181554-181585	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029957	Salmonella enterica subsp. enterica serovar Typhi strain 311189_201186 plasmid pHCM1, complete sequence	182609-182640	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029941	Salmonella enterica subsp. enterica serovar Typhi strain 311189_203186 plasmid pHCM1, complete sequence	182936-182967	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029910	Salmonella enterica subsp. enterica serovar Typhi strain 311189_219186 plasmid pHCM1, complete sequence	182844-182875	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029887	Salmonella enterica subsp. enterica serovar Typhi strain 311189_220186 plasmid pHCM1, complete sequence	182670-182701	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029948	Salmonella enterica subsp. enterica serovar Typhi strain 311189_208186 plasmid pHCM1, complete sequence	183046-183077	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029937	Salmonella enterica subsp. enterica serovar Typhi strain 311189_207186 plasmid pHCM1, complete sequence	182572-182603	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029879	Salmonella enterica subsp. enterica serovar Typhi strain 311189_223186 plasmid pHCM1, complete sequence	180358-180389	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP018656	Salmonella enterica subsp. enterica serovar Enteritidis strain 81-1706 plasmid pSE81-1706, complete sequence	176026-176057	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NC_016825	Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12 plasmid unnamed, complete sequence	130052-130083	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029931	Salmonella enterica subsp. enterica serovar Typhi strain 311189_215186 plasmid pHCM1, complete sequence	182677-182708	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_CP029935	Salmonella enterica subsp. enterica serovar Typhi strain 311189_213186 plasmid pHCM1, complete sequence	182461-182492	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_LT985296	Escherichia coli strain 1454 plasmid RCS78_p, complete sequence	41577-41608	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_MN101858	Escherichia coli strain 2019XSD11-TC2 plasmid p2019XSD11-TC2-284, complete sequence	203153-203184	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_MN101856	Escherichia coli strain 2019XSD11 plasmid p2019XSD11-190, complete sequence	109234-109265	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_MH733010	Klebsiella pneumoniae strain KP14812 plasmid pKP14812-MCR-1, complete sequence	20553-20584	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	MT219825	Escherichia coli strain RW7-1 plasmid pRW7-1_235k_tetX, complete sequence	58755-58786	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NZ_MG948335	Escherichia coli strain 3498 plasmid p3498, complete sequence	179219-179250	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NC_023277	Escherichia coli strain 63743 plasmid pEQ2, complete sequence	194749-194780	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	NC_023289	Escherichia coli strain T23 plasmid pEQ1, complete sequence	146284-146315	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	MT219824	Escherichia coli strain RT18-1 plasmid pRT18-1_294k_tetX, complete sequence	176467-176498	10	0.688
LR134295_2	2.6\|1021513\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021513-1021544	32	MG874042	Salmonella sp. strain Sa4 plasmid pSa4-CIP, complete sequence	45801-45832	10	0.688
LR134295_2	2.8\|1021635\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021635-1021666	32	LR134122	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2	259269-259300	10	0.688
LR134295_2	2.17\|1022184\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1022184-1022215	32	NZ_CP041349	Komagataeibacter xylinus strain CGMCC 17276 plasmid pA, complete sequence	27173-27204	10	0.688
LR134295_2	2.17\|1022184\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1022184-1022215	32	NZ_CP041350	Komagataeibacter xylinus strain CGMCC 17276 plasmid pB, complete sequence	149091-149122	10	0.688
LR134295_2	2.17\|1022184\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1022184-1022215	32	NZ_CP004365	Komagataeibacter xylinus E25 plasmid pGX5, complete sequence	172655-172686	10	0.688
LR134295_2	2.19\|1022306\|32\|LR134295\|CRISPRCasFinder,CRT	1022306-1022337	32	NC_047894	Pseudomonas phage uligo, complete genome	11353-11384	10	0.688
LR134295_1	1.1\|995264\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995264-995296	33	MN694016	Marine virus AFVG_250M811, complete genome	5413-5445	11	0.667
LR134295_1	1.1\|995264\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995264-995296	33	MN694190	Marine virus AFVG_250M608, complete genome	5350-5382	11	0.667
LR134295_1	1.1\|995264\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995264-995296	33	MN693920	Marine virus AFVG_250M810, complete genome	5422-5454	11	0.667
LR134295_1	1.1\|995264\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995264-995296	33	MN693800	Marine virus AFVG_250M813, complete genome	5404-5436	11	0.667
LR134295_1	1.1\|995264\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995264-995296	33	MN694554	Marine virus AFVG_250M812, complete genome	5416-5448	11	0.667
LR134295_1	1.1\|995264\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995264-995296	33	MN694404	Marine virus AFVG_250M623, complete genome	5369-5401	11	0.667
LR134295_1	1.1\|995264\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995264-995296	33	MN694355	Marine virus AFVG_250M627, complete genome	26039-26071	11	0.667
LR134295_1	1.4\|995447\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995447-995479	33	MF158039	Shigella phage Sf12, complete genome	4974-5006	11	0.667
LR134295_1	1.4\|995447\|33\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	995447-995479	33	MF158042	Shigella phage Sd1, complete genome	937-969	11	0.667
LR134295_2	2.7\|1021574\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021574-1021605	32	MT344105	Acinetobacter phage fLi-Aba03, complete genome	32699-32730	11	0.656
LR134295_2	2.7\|1021574\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021574-1021605	32	MT344104	Acinetobacter phage fLi-Aba02, complete genome	32861-32892	11	0.656
LR134295_2	2.7\|1021574\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1021574-1021605	32	MT344103	Acinetobacter phage fEg-Aba01, complete genome	31614-31645	11	0.656
LR134295_2	2.14\|1022001\|32\|LR134295\|PILER-CR,CRISPRCasFinder,CRT	1022001-1022032	32	MN694507	Marine virus AFVG_250M1178, complete genome	3229-3260	11	0.656

1. spacer 2.8|1021635|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP042584 (Escherichia coli strain LD91-1 plasmid pLD91-1-76kb, complete sequence) position: , mismatch: 0, identity: 1.0

tcatgaatatggggaaaacgaacaatctgttt	CRISPR spacer
tcatgaatatggggaaaacgaacaatctgttt	Protospacer
********************************

2. spacer 5.1|2854483|40|LR134295|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 0, identity: 1.0

gcgctgcgggtcattcttgaaattacccccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
****************************************

3. spacer 6.1|3155204|24|LR134295|PILER-CR matches to NC_049946 (Escherichia virus Lambda_4A7 genome assembly, chromosome: 1) position: , mismatch: 0, identity: 1.0

cgcctttacctgatttgggtaaac	CRISPR spacer
cgcctttacctgatttgggtaaac	Protospacer
************************

4. spacer 6.1|3155204|24|LR134295|PILER-CR matches to LR595861 (Escherichia virus Lambda_4C10 genome assembly, chromosome: 1) position: , mismatch: 0, identity: 1.0

cgcctttacctgatttgggtaaac	CRISPR spacer
cgcctttacctgatttgggtaaac	Protospacer
************************

5. spacer 6.2|3155251|25|LR134295|PILER-CR matches to NC_049946 (Escherichia virus Lambda_4A7 genome assembly, chromosome: 1) position: , mismatch: 0, identity: 1.0

tttacctctttcaggtaaactttat	CRISPR spacer
tttacctctttcaggtaaactttat	Protospacer
*************************

6. spacer 6.2|3155251|25|LR134295|PILER-CR matches to LR595861 (Escherichia virus Lambda_4C10 genome assembly, chromosome: 1) position: , mismatch: 0, identity: 1.0

tttacctctttcaggtaaactttat	CRISPR spacer
tttacctctttcaggtaaactttat	Protospacer
*************************

7. spacer 2.19|1022306|32|LR134295|CRISPRCasFinder,CRT matches to LC542972 (Escherichia coli IOMTU792 plasmid pIOMTU792 DNA, complete sequence) position: , mismatch: 1, identity: 0.969

gacgcactggatgcgatgatggatatcacttg	CRISPR spacer
gacgcactggatgcgatgatggacatcacttg	Protospacer
***********************.********

8. spacer 6.1|3155204|24|LR134295|PILER-CR matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 1, identity: 0.958

cgcctttacctgatttgggtaaac	CRISPR spacer
tgcctttacctgatttgggtaaac	Protospacer
.***********************

9. spacer 6.2|3155251|25|LR134295|PILER-CR matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 1, identity: 0.96

tttacctctttcaggtaaactttat	CRISPR spacer
tttacctctttaaggtaaactttat	Protospacer
*********** *************

10. spacer 4.1|2186063|38|LR134295|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

11. spacer 1.4|995447|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134258 (Klebsiella aerogenes strain NCTC9644 plasmid 5, complete sequence) position: , mismatch: 4, identity: 0.879

tgtgtttgcggcattaacgctcaccagcatttc	CRISPR spacer
ggggttcgcggcgttaacgctcaccagcatttc	Protospacer
 * ***.*****.********************

12. spacer 1.4|995447|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to LR134281 (Klebsiella aerogenes strain NCTC9793 genome assembly, plasmid: 6) position: , mismatch: 4, identity: 0.879

tgtgtttgcggcattaacgctcaccagcatttc	CRISPR spacer
ggggttcgcggcgttaacgctcaccagcatttc	Protospacer
 * ***.*****.********************

13. spacer 1.4|995447|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to KY271401 (Klebsiella phage 1 LV-2017, complete genome) position: , mismatch: 4, identity: 0.879

tgtgtttgcggcattaacgctcaccagcatttc	CRISPR spacer
ggggttcgcggcgttaacgctcaccagcatttc	Protospacer
 * ***.*****.********************

14. spacer 2.11|1021818|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MF547662 (Clostridioides phage LIBA6276, complete genome) position: , mismatch: 4, identity: 0.875

tacagtttccataaattcacctcgtttatata-	CRISPR spacer
tactgtttccataaattcacctc-cttataaaa	Protospacer
*** ******************* .***** *

15. spacer 2.11|1021818|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MF547663 (Clostridioides phage LIBA2945, complete genome) position: , mismatch: 4, identity: 0.875

tacagtttccataaattcacctcgtttatata-	CRISPR spacer
tactgtttccataaattcacctc-cttataaaa	Protospacer
*** ******************* .***** *

16. spacer 6.2|3155251|25|LR134295|PILER-CR matches to NZ_CP015341 (Lactobacillus brevis strain 100D8 plasmid unnamed3, complete sequence) position: , mismatch: 4, identity: 0.84

tttacctctttcaggtaaactttat	CRISPR spacer
ggtatctcattcaggtaaactttat	Protospacer
  **.*** ****************

17. spacer 2.8|1021635|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NC_014108 (Enterobacter cloacae subsp. cloacae ATCC 13047 plasmid pECL_B, complete sequence) position: , mismatch: 5, identity: 0.844

tcatgaatatggggaaaacgaacaatctgttt	CRISPR spacer
tcatgaatatggcgaaaatgaacaatcagcct	Protospacer
************ *****.******** *..*

18. spacer 2.8|1021635|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030922 (Escherichia coli strain KL53 plasmid pKL53-S, complete sequence) position: , mismatch: 5, identity: 0.844

tcatgaatatggggaaaacgaacaatctgttt	CRISPR spacer
tcatgaatatggcgaaaatgaacaatcagcct	Protospacer
************ *****.******** *..*

19. spacer 2.8|1021635|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP038659 (Citrobacter freundii strain 680 plasmid p680_1, complete sequence) position: , mismatch: 5, identity: 0.844

tcatgaatatggggaaaacgaacaatctgttt	CRISPR spacer
tcatgaatatggcgaaaatgaacaatcagcct	Protospacer
************ *****.******** *..*

20. spacer 2.8|1021635|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN699848 (Citrobacter pasteurii strain 175G8 plasmid pCfr-OXA-198, complete sequence) position: , mismatch: 5, identity: 0.844

tcatgaatatggggaaaacgaacaatctgttt	CRISPR spacer
tcatgaatatggcgaaaatgaacaatcagcct	Protospacer
************ *****.******** *..*

21. spacer 2.11|1021818|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029155 (Clostridioides difficile strain CD161 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

tacagtttccataaattcacctcgtttatata-	CRISPR spacer
tactgtttccataaattcacctc-cctataaaa	Protospacer
*** ******************* ..**** *

22. spacer 1.4|995447|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to KY653119 (Morganella phage IME1369_02, complete genome) position: , mismatch: 6, identity: 0.818

tgtgtttgcggcattaacgctcaccagcatttc	CRISPR spacer
aggttgtgcggcgttaacgctgaccagcatttc	Protospacer
 *  * ******.******** ***********

23. spacer 2.4|1021391|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018520 (Sphingobium sp. YG1 plasmid pYGP1, complete sequence) position: , mismatch: 6, identity: 0.812

ggcgagtccgtcagcggtgcgccgctg-caaca	CRISPR spacer
gtcgagtaagtcagcggtgcgccgcgatcaac-	Protospacer
* *****  **************** . ****

24. spacer 2.12|1021879|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025114 (Bradyrhizobium sp. SK17 strain CBNU plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.812

atcggacg-atggcgatcgcaatcgcgcgggaa	CRISPR spacer
-ttagacgcatggcgattgcaatcgcgtgggat	Protospacer
 *..**** ********.*********.****

25. spacer 2.12|1021879|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044544 (Bradyrhizobium betae strain PL7HG1 plasmid pBbPL7HG1, complete sequence) position: , mismatch: 6, identity: 0.812

atcggacg-atggcgatcgcaatcgcgcgggaa	CRISPR spacer
-ttagacgcatggcgattgcaatcgcgtgggat	Protospacer
 *..**** ********.*********.****

26. spacer 2.19|1022306|32|LR134295|CRISPRCasFinder,CRT matches to MK455769 (Aeromonas phage MJG, complete genome) position: , mismatch: 7, identity: 0.781

gacgcactggatgcgatgatggatatcacttg-	CRISPR spacer
gacgcactgtatgcaatgatgga-atcggaggc	Protospacer
********* ****.******** ***.   *

27. spacer 2.3|1021330|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NC_018454 (Cronobacter phage phiES15, complete genome) position: , mismatch: 8, identity: 0.75

atccgccgccggttaacgctggaccagttccg	CRISPR spacer
gcgtggccccggttaacgctggacacgttccg	Protospacer
.. .* * ****************  ******

28. spacer 2.3|1021330|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to JQ780327 (Cronobacter phage phiES15, complete sequence) position: , mismatch: 8, identity: 0.75

atccgccgccggttaacgctggaccagttccg	CRISPR spacer
gcgtggccccggttaacgctggacacgttccg	Protospacer
.. .* * ****************  ******

29. spacer 2.17|1022184|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013415 (Burkholderia ubonensis strain MSMB2035 plasmid pMSMB2035, complete sequence) position: , mismatch: 8, identity: 0.75

ccaggacaggccgtgacggttgccattgagtc	CRISPR spacer
aatctacaggccgtgacggttgtcatggaggc	Protospacer
     *****************.*** *** *

30. spacer 2.5|1021452|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009595 (Bacillus cereus strain 3a plasmid pBFC_3, complete sequence) position: , mismatch: 9, identity: 0.719

ggacaatgtgaaaagcttaatattcattacat	CRISPR spacer
aaggaaaatgaaaagaataatattcattacag	Protospacer
... ** .*******  **************

31. spacer 2.5|1021452|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009606 (Bacillus cereus strain S2-8 plasmid pBFR_2, complete sequence) position: , mismatch: 9, identity: 0.719

ggacaatgtgaaaagcttaatattcattacat	CRISPR spacer
aaggaaaatgaaaagaataatattcattacag	Protospacer
... ** .*******  **************

32. spacer 2.5|1021452|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053994 (Bacillus cereus strain FDAARGOS_780 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

ggacaatgtgaaaagcttaatattcattacat	CRISPR spacer
aaggaaaatgaaaagaataatattcattacag	Protospacer
... ** .*******  **************

33. spacer 2.5|1021452|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053992 (Bacillus cereus strain FDAARGOS_781 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.719

ggacaatgtgaaaagcttaatattcattacat	CRISPR spacer
aaggaaaatgaaaagaataatattcattacag	Protospacer
... ** .*******  **************

34. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024236 (Escherichia coli O6:H16 strain 2014EL-1346-6 plasmid unnamed4, complete sequence) position: , mismatch: 9, identity: 0.719

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatatcacccagcactccggg	Protospacer
  *  ******************** ** .

35. spacer 2.8|1021635|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045296 (Paenibacillus cellulositrophicus strain KACC 16577 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

tcatgaatatggggaaaacgaacaatctgttt	CRISPR spacer
tctgctgcatgggggaaacgatcaatctgttg	Protospacer
**    ..******.****** *********

36. spacer 2.11|1021818|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN693584 (Marine virus AFVG_25M163, complete genome) position: , mismatch: 9, identity: 0.719

tacagtttccataaattcacctcgtttatata	CRISPR spacer
ggggatatctataaactcacctcgtttatatt	Protospacer
 . ..* **.*****.***************

37. spacer 2.11|1021818|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN103543 (Pseudomonas phage vB_PaeM_PS119XW, complete genome) position: , mismatch: 9, identity: 0.719

tacagtttccataaattcacctcgtttatata	CRISPR spacer
cgcttcttccatacattcacctcggttatgga	Protospacer
..*  .******* ********** ****. *

38. spacer 2.11|1021818|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MK599315 (Pseudomonas phage PA1C, complete genome) position: , mismatch: 9, identity: 0.719

tacagtttccataaattcacctcgtttatata	CRISPR spacer
cgcttcttccatacattcacctcggttatgga	Protospacer
..*  .******* ********** ****. *

39. spacer 2.12|1021879|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054028 (Rhizobium sp. JKLM19E plasmid pPR19E01, complete sequence) position: , mismatch: 9, identity: 0.719

atcggacgatggcgatcgcaatcgcgcgggaa	CRISPR spacer
aaaagacgatggcgatcgcaatcgtgcctttc	Protospacer
*  .********************.**

40. spacer 2.15|1022062|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to AP014022 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C112A-MedDCM-OCT-S32-C75, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ccagccgaaacaacgccagcaaaatcgaccgc	CRISPR spacer
ccagccaaaacatcgccagcaaaaccttggag	Protospacer
******.***** ***********.*    .

41. spacer 2.15|1022062|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to AP014023 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C112A-MedDCM-OCT-S35-C64, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.719

ccagccgaaacaacgccagcaaaatcgaccgc	CRISPR spacer
ccagccaaaacatcgccagcaaaaccctggag	Protospacer
******.***** ***********.*    .

42. spacer 2.17|1022184|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014797 (Salipiger profundus strain JLT2016 plasmid pTPRO1, complete sequence) position: , mismatch: 9, identity: 0.719

ccaggacaggccgtgacggttgccattgagtc	CRISPR spacer
gctgcacagggtgtgacggttgccattgccga	Protospacer
 * * ***** .****************

43. spacer 2.19|1022306|32|LR134295|CRISPRCasFinder,CRT matches to NC_047954 (Pseudomonas phage Njord, complete genome) position: , mismatch: 9, identity: 0.719

gacgcactggatgcgatgatggatatcacttg	CRISPR spacer
gacgcactcgatgcgatgatggaggccgaggc	Protospacer
******** ************** ..*.

44. spacer 2.2|1021269|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027239 (Dietzia sp. oral taxon 368 strain W5195 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

ggcacggaattgttatgctgttcccctgaccg	CRISPR spacer
tcttcggaattgccatgctgttccccttccat	Protospacer
  . ********..*************  *

45. spacer 2.4|1021391|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021914 (Sagittula sp. P11 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

ggcgagtccgtcagcggtgcgccgctgcaaca	CRISPR spacer
ttggagtccgacatcggtgcgccgcttttcga	Protospacer
   ******* ** ************ .   *

46. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT904879 (Salmonella enterica subsp. enterica serovar Typhi strain ty3-193 genome assembly, plasmid: 2) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

47. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KX129784 (Escherichia coli strain H226B plasmid pH226B, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

48. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NC_009981 (Salmonella enterica subsp. enterica serovar Choleraesuis plasmid pMAK1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

49. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029645 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_217186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

50. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053721 (Escherichia coli strain CP131_Sichuan plasmid pCP131-IncHI1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

51. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026790 (Shigella flexneri 2a strain ATCC 29903 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

52. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039717 (Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS000211 plasmid p10-3184.1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

53. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to KP899804 (Salmonella enterica strain F8475 plasmid pF8475, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

54. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to KP899805 (Salmonella enterica strain 109/9 plasmid p109/9, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

55. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP037875 (Salmonella enterica subsp. enterica serovar 4,[5],12:i:- strain PNCS015054 plasmid pPNCS015054_S2, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

56. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018652 (Salmonella enterica subsp. enterica serovar Enteritidis strain 81-1705 plasmid pSE81-1705-1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

57. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044299 (Escherichia coli strain P59A plasmid pP59A-CTX-M-55, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

58. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029690 (Escherichia coli strain SD134209 plasmid pSD134209-1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

59. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NC_003384 (Salmonella enterica subsp. enterica serovar Typhi str. CT18 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

60. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049354 (Escherichia coli strain T28R plasmid pT28R-1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

61. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to AP020333 (Salmonella enterica SESen3709 plasmid pSESen3709_1 DNA, complete genome) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

62. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039559 (Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS014846 plasmid p08-4425.1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

63. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP037911 (Escherichia coli strain YSP8-1 plasmid pYSP8-1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

64. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046717 (Escherichia coli strain T16R plasmid pT16R-1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

65. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046007 (Escherichia coli strain 1919D62 plasmid p1919D62-1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

66. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NC_002305 (Salmonella typhi plasmid R27, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

67. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046004 (Escherichia coli strain 1919D3 plasmid p1919D3-1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

68. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029895 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_252186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

69. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029877 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_224186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

70. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033094 (Escherichia coli strain CP53 plasmid pCP53-mcr, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

71. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to LT905061 (Salmonella enterica subsp. enterica serovar Typhi isolate ISP_03_07467_SGB110-sc-1979083 genome assembly, plasmid: 2) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

72. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029926 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_218186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

73. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029947 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_210186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

74. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044968 (Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS007098 plasmid pPNCS014881.1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

75. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044958 (Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS007087 plasmid pPNCS007087.1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

76. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029943 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_212186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

77. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029953 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_204186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

78. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029955 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_202186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

79. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022495 (Salmonella enterica subsp. enterica serovar Derby strain SA20035215 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

80. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016184 (Escherichia coli strain EC2 plasmid pEC2-4, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

81. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016183 (Escherichia coli strain EC2_1 plasmid pEC2_1-4, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

82. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029924 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_221186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

83. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029934 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_214186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

84. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NC_013365 (Escherichia coli O111:H- str. 11128 plasmid pO111_1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

85. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041449 (Escherichia coli strain YPE10 plasmid pYPE10-190k-tetX4, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

86. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029939 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_206186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

87. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029957 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_201186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

88. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029941 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_203186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

89. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029910 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_219186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

90. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029887 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_220186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

91. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029948 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_208186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

92. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029937 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_207186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

93. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029879 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_223186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

94. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018656 (Salmonella enterica subsp. enterica serovar Enteritidis strain 81-1706 plasmid pSE81-1706, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

95. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NC_016825 (Salmonella enterica subsp. enterica serovar Typhi str. P-stx-12 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

96. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029931 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_215186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

97. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029935 (Salmonella enterica subsp. enterica serovar Typhi strain 311189_213186 plasmid pHCM1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

98. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LT985296 (Escherichia coli strain 1454 plasmid RCS78_p, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

99. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MN101858 (Escherichia coli strain 2019XSD11-TC2 plasmid p2019XSD11-TC2-284, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

100. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MN101856 (Escherichia coli strain 2019XSD11 plasmid p2019XSD11-190, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

101. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MH733010 (Klebsiella pneumoniae strain KP14812 plasmid pKP14812-MCR-1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

102. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MT219825 (Escherichia coli strain RW7-1 plasmid pRW7-1_235k_tetX, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

103. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_MG948335 (Escherichia coli strain 3498 plasmid p3498, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

104. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NC_023277 (Escherichia coli strain 63743 plasmid pEQ2, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

105. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NC_023289 (Escherichia coli strain T23 plasmid pEQ1, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

106. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MT219824 (Escherichia coli strain RT18-1 plasmid pRT18-1_294k_tetX, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

107. spacer 2.6|1021513|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MG874042 (Salmonella sp. strain Sa4 plasmid pSa4-CIP, complete sequence) position: , mismatch: 10, identity: 0.688

cgacgttttctaatatcacccagcaatcaatt	CRISPR spacer
gtaacttttctaatctcacccagcactccggg	Protospacer
  *  ********* ********** ** .

108. spacer 2.8|1021635|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to LR134122 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 2) position: , mismatch: 10, identity: 0.688

tcatgaatatggggaaaacgaacaatctgttt	CRISPR spacer
agctgaatatggggaaaatgcacaatatcccc	Protospacer
   ***************.* ***** * ...

109. spacer 2.17|1022184|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041349 (Komagataeibacter xylinus strain CGMCC 17276 plasmid pA, complete sequence) position: , mismatch: 10, identity: 0.688

ccaggacaggccgtgacggttgccattgagtc	CRISPR spacer
gacggacaggccgccacggttgccatcaggaa	Protospacer
   **********. ***********...*

110. spacer 2.17|1022184|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041350 (Komagataeibacter xylinus strain CGMCC 17276 plasmid pB, complete sequence) position: , mismatch: 10, identity: 0.688

ccaggacaggccgtgacggttgccattgagtc	CRISPR spacer
gatggacaggctgtgacggtcgccatcaggaa	Protospacer
   ********.********.*****...*

111. spacer 2.17|1022184|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP004365 (Komagataeibacter xylinus E25 plasmid pGX5, complete sequence) position: , mismatch: 10, identity: 0.688

ccaggacaggccgtgacggttgccattgagtc	CRISPR spacer
gatggacaggctgtgacggtcgccatcaggaa	Protospacer
   ********.********.*****...*

112. spacer 2.19|1022306|32|LR134295|CRISPRCasFinder,CRT matches to NC_047894 (Pseudomonas phage uligo, complete genome) position: , mismatch: 10, identity: 0.688

gacgcactggatgcgatgatggatatcacttg	CRISPR spacer
gacgcactcgatgcgatgatggaggcagaagc	Protospacer
******** ************** .. .

113. spacer 1.1|995264|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN694016 (Marine virus AFVG_250M811, complete genome) position: , mismatch: 11, identity: 0.667

gcggcccataatattaatataatccacatgagg	CRISPR spacer
ttcttccataatatcaatataatccatatactt	Protospacer
 .  .*********.***********.**.

114. spacer 1.1|995264|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN694190 (Marine virus AFVG_250M608, complete genome) position: , mismatch: 11, identity: 0.667

gcggcccataatattaatataatccacatgagg	CRISPR spacer
ttcttccataatatcaatataatccatatacct	Protospacer
 .  .*********.***********.**.

115. spacer 1.1|995264|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN693920 (Marine virus AFVG_250M810, complete genome) position: , mismatch: 11, identity: 0.667

gcggcccataatattaatataatccacatgagg	CRISPR spacer
ttcttccataatatcaatataatccatatactt	Protospacer
 .  .*********.***********.**.

116. spacer 1.1|995264|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN693800 (Marine virus AFVG_250M813, complete genome) position: , mismatch: 11, identity: 0.667

gcggcccataatattaatataatccacatgagg	CRISPR spacer
ttcttccataatatcaatataatccatatactt	Protospacer
 .  .*********.***********.**.

117. spacer 1.1|995264|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN694554 (Marine virus AFVG_250M812, complete genome) position: , mismatch: 11, identity: 0.667

gcggcccataatattaatataatccacatgagg	CRISPR spacer
ttcttccataatatcaatataatccatatactt	Protospacer
 .  .*********.***********.**.

118. spacer 1.1|995264|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN694404 (Marine virus AFVG_250M623, complete genome) position: , mismatch: 11, identity: 0.667

gcggcccataatattaatataatccacatgagg	CRISPR spacer
ttcttccataatatcaatataatccatatacct	Protospacer
 .  .*********.***********.**.

119. spacer 1.1|995264|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN694355 (Marine virus AFVG_250M627, complete genome) position: , mismatch: 11, identity: 0.667

gcggcccataatattaatataatccacatgagg	CRISPR spacer
ttcttccataatatcaatataatccatatactt	Protospacer
 .  .*********.***********.**.

120. spacer 1.4|995447|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MF158039 (Shigella phage Sf12, complete genome) position: , mismatch: 11, identity: 0.667

tgtgtttgcggcattaacgctcaccagcatttc	CRISPR spacer
attgtttgcagcattaacgctccccaagtgccg	Protospacer
  *******.************ ***.   ..

121. spacer 1.4|995447|33|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MF158042 (Shigella phage Sd1, complete genome) position: , mismatch: 11, identity: 0.667

tgtgtttgcggcattaacgctcaccagcatttc	CRISPR spacer
attgtttgcagcattaacgctctccaagtgccg	Protospacer
  *******.************ ***.   ..

122. spacer 2.7|1021574|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MT344105 (Acinetobacter phage fLi-Aba03, complete genome) position: , mismatch: 11, identity: 0.656

atttcatcaaagcattaagggatggaataaag	CRISPR spacer
ctttcatcaaagtattaatggatgatggttca	Protospacer
 ***********.***** *****. .    .

123. spacer 2.7|1021574|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MT344104 (Acinetobacter phage fLi-Aba02, complete genome) position: , mismatch: 11, identity: 0.656

atttcatcaaagcattaagggatggaataaag	CRISPR spacer
ctttcatcaaagtattaatggatgatggttca	Protospacer
 ***********.***** *****. .    .

124. spacer 2.7|1021574|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MT344103 (Acinetobacter phage fEg-Aba01, complete genome) position: , mismatch: 11, identity: 0.656

atttcatcaaagcattaagggatggaataaag	CRISPR spacer
ctttcatcaaagtattaatggatgatggttca	Protospacer
 ***********.***** *****. .    .

125. spacer 2.14|1022001|32|LR134295|PILER-CR,CRISPRCasFinder,CRT matches to MN694507 (Marine virus AFVG_250M1178, complete genome) position: , mismatch: 11, identity: 0.656

aaccttgtcgggtcgcccgtgcgtcatgatga	CRISPR spacer
tggtatgtcgggtagcccgtgcgccatgcccg	Protospacer
 . . ******** *********.**** . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1029730 : 1042913

Escherichia_phage(40.0%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE27246.1\|1029730_1030492_+	stationary phase survival protein SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.4e-59	48.0
VEE27248.1\|1030485_1031112_+	protein-L-isoaspartate O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	5.7e-36	49.7
VEE27250.1\|1031251_1032391_+	lipoprotein NlpD	D7RWE0	Brochothrix_phage	1.7e-06	35.6
VEE27252.1\|1032453_1033446_+	RNA polymerase sigma factor RpoS	G8CLC7	Synechococcus_phage	6.7e-31	37.3
VEE27254.1\|1033539_1034904_-	inner membrane permease YgbN	NA	NA	NA	NA
VEE27256.1\|1034992_1035769_-	hydroxypyruvate isomerase	NA	NA	NA	NA
VEE27258.1\|1035773_1036412_-	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	75.0
VEE27260.1\|1036408_1037671_-\|tRNA	paral putative tRNA synthase	A0A077SLJ7	Escherichia_phage	6.3e-135	61.2
VEE27262.1\|1037667_1038576_-	oxidoreductase YgbJ	A0A077SLF7	Escherichia_phage	3.0e-118	76.9
VEE27264.1\|1038771_1039539_+	DeoR family transcriptional regulator	A0A077SK06	Escherichia_phage	2.5e-70	56.7
VEE27266.1\|1039589_1040246_-	serine/threonine-specific protein phosphatase 2	K7P7V3	Enterobacteria_phage	5.6e-50	45.3
VEE27268.1\|1040351_1042913_-	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	3.9e-30	20.6

DBSCAN-SWA_2

1648262 : 1657704

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE28746.1\|1648262_1649189_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.7e-23	30.8
VEE28749.1\|1649193_1649925_+	ABC transporter permease	NA	NA	NA	NA
VEE28752.1\|1649905_1650013_-	putative inner membrane protein	NA	NA	NA	NA
VEE28755.1\|1650072_1650804_-	MerR family transcriptional regulator	Q9EYF2	Enterobacteria_phage	9.7e-112	99.5
VEE28758.1\|1651025_1652711_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
VEE28761.1\|1652707_1653427_+	two-component response-regulatory protein YehT	NA	NA	NA	NA
VEE28764.1\|1653473_1653944_+	conserved protein, DUF1456 family	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
VEE28768.1\|1653984_1654446_-	lipoprotein yehR	Q9EYF5	Enterobacteria_phage	1.6e-75	98.7
VEE28771.1\|1654570_1656571_-	zinc finger SWIM domain-containing protein	Q9EYF6	Enterobacteria_phage	0.0e+00	96.6
VEE28774.1\|1656567_1657704_-	von Willebrand factor type A domain protein YehP	Q9EYF7	Enterobacteria_phage	1.9e-162	97.7

DBSCAN-SWA_3

1669336 : 1704049

Shigella_phage(22.22%)

integrase,protease,transposase,tRNA

attL 1673829:1673888|attR 1698313:1699080

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE28792.1\|1669336_1671370_-\|tRNA	methionyl-tRNA synthetase	A0A1V0SDF2	Indivirus	2.3e-54	27.6
VEE28795.1\|1671501_1672611_+	ATPase	NA	NA	NA	NA
VEE28798.1\|1672873_1673155_+	fimbrial-like adhesin protein	NA	NA	NA	NA
VEE28801.1\|1673447_1673855_+	fimbrial protein	NA	NA	NA	NA
1673829:1673888	attL	NA	NA	NA	NA
VEE28804.1\|1673883_1674159_+\|transposase	IS1 transposase	NA	NA	NA	NA
VEE28807.1\|1674203_1674581_+\|transposase	IS1 transposase	U5P0U6	Shigella_phage	1.3e-67	100.0
VEE28810.1\|1674688_1674979_+	fimbrial-like adhesin protein StcD	NA	NA	NA	NA
VEE28813.1\|1675060_1675399_-	periplasmic modulator of Ni and Co efflux	NA	NA	NA	NA
VEE28816.1\|1675617_1676442_-	nickel/cobalt efflux protein RcnA	NA	NA	NA	NA
VEE28819.1\|1676562_1676835_+	transcriptional repressor RcnR	NA	NA	NA	NA
VEE28822.1\|1677088_1678393_+\|integrase	integrase	NA	NA	NA	NA
VEE28825.1\|1678791_1679742_+	Uncharacterised protein	A0A1B1ITH5	uncultured_Mediterranean_phage	2.7e-29	29.9
VEE28828.1\|1680072_1680420_-	Uncharacterised protein	NA	NA	NA	NA
VEE28831.1\|1680756_1680846_+	Uncharacterised protein	NA	NA	NA	NA
VEE28834.1\|1681159_1681711_-	resolvase domain-containing protein	Q2A092	Sodalis_phage	4.6e-29	43.3
VEE28837.1\|1683475_1683658_+	Uncharacterised protein	NA	NA	NA	NA
VEE28840.1\|1683804_1684524_+	Uncharacterised protein	NA	NA	NA	NA
VEE28843.1\|1684507_1684780_+	Uncharacterised protein	NA	NA	NA	NA
VEE28846.1\|1685530_1686319_+	hydroxyethylthiazole kinase	NA	NA	NA	NA
VEE28849.1\|1686315_1687116_+	phosphomethylpyrimidine kinase	NA	NA	NA	NA
VEE28852.1\|1687180_1687999_+	1,4-beta-N-acetylmuramidase	D0R7H8	Paenibacillus_phage	2.9e-24	38.5
VEE28855.1\|1688050_1688797_+	GntR family transcriptional regulator	NA	NA	NA	NA
VEE28858.1\|1688770_1689736_-	putative carbohydrate/pyrimidine kinase	NA	NA	NA	NA
VEE28861.1\|1689732_1690737_-	putative ADP-ribosylglycohydrolase	A0A1S6UB21	Serratia_phage	7.5e-14	29.4
VEE28864.1\|1690733_1692011_-	major facilitator superfamily protein	NA	NA	NA	NA
VEE28867.1\|1692267_1693320_+	fructose-bisphosphate aldolase	NA	NA	NA	NA
VEE28870.1\|1693628_1694114_+	tagatose-bisphosphate aldolase	NA	NA	NA	NA
VEE28874.1\|1694171_1694483_+	tagatose-bisphosphate aldolase	NA	NA	NA	NA
VEE28877.1\|1694511_1695774_+	putative tagatose 6-phosphate kinase	NA	NA	NA	NA
VEE28880.1\|1695783_1696236_+	galactitol-specific PTS system EIIA component	NA	NA	NA	NA
VEE28883.1\|1696266_1696551_+	galactitol-specific PTS system EIIB component	NA	NA	NA	NA
VEE28886.1\|1696554_1697910_+	galactitol-specific PTS system EIIC component	NA	NA	NA	NA
VEE28889.1\|1697957_1698317_+	galactitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
VEE28892.1\|1698367_1698643_+\|transposase	IS1 transposase	NA	NA	NA	NA
VEE28895.1\|1698687_1699065_+\|transposase	IS1 transposase	U5P0U6	Shigella_phage	1.3e-67	100.0
VEE28898.1\|1699136_1699775_+	galactitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
1698313:1699080	attR	NA	NA	NA	NA
VEE28901.1\|1699874_1700654_+	galactitol utilization operon repressor	NA	NA	NA	NA
VEE28904.1\|1700735_1701635_-	lipid kinase	A0A1V0SBJ0	Catovirus	1.3e-12	29.0
VEE28907.1\|1702039_1702357_+	protein	NA	NA	NA	NA
VEE28910.1\|1702687_1704049_-\|protease	putative protease	Q6DW11	Phage_TP	1.9e-217	99.7

DBSCAN-SWA_4

1753700 : 1763244

Bacillus_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE29023.1\|1753700_1755095_+	colanic acid biosynthesis protein	A0A291LBB9	Klebsiella_phage	8.3e-19	31.9
VEE29026.1\|1755269_1756163_+	UTP--glucose-1-phosphate uridylyltransferase subunit GalF	A0A127AW70	Bacillus_phage	1.0e-46	42.0
VEE29029.1\|1756491_1757505_+	UDP-galactose-4-epimerase	A0A2K9L5H6	Tupanvirus	2.8e-85	50.0
VEE29032.1\|1757835_1758954_+	GDP-mannose 4,6-dehydratase	M4QRT5	Synechococcus_phage	1.4e-133	65.8
VEE29035.1\|1758957_1759923_+	GDP-L-fucose synthetase	D1LW79	Prochlorococcus_phage	6.4e-87	50.8
VEE29038.1\|1759922_1760426_+	GDP-mannose mannosyl hydrolase	NA	NA	NA	NA
VEE29041.1\|1760418_1761867_+	GDP-mannose pyrophosphorylase	A0A1V0SH58	Hokovirus	4.8e-54	31.4
VEE29044.1\|1761870_1763244_+	phosphomannomutase CpsG	A0A127AWJ1	Bacillus_phage	2.2e-32	27.9

DBSCAN-SWA_5

1838135 : 1861800

Pseudomonas_phage(40.0%)

integrase,transposase

attL 1841969:1842028|attR 1861963:1862042

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE29253.1\|1838135_1838774_-\|integrase	phage integrase	A0A1B0VMI6	Pseudomonas_phage	1.1e-29	42.3
VEE29256.1\|1838867_1839398_-\|integrase	bacteriophage integrase	B7SYF8	Stenotrophomonas_phage	1.4e-30	42.7
VEE29259.1\|1839961_1840879_+	Nitrogen assimilation regulatory protein nac	NA	NA	NA	NA
VEE29262.1\|1840980_1841931_+	LysR family transcriptional regulator	NA	NA	NA	NA
1841969:1842028	attL	NA	NA	NA	NA
VEE29265.1\|1842237_1843692_+	multidrug efflux system	NA	NA	NA	NA
VEE29268.1\|1844320_1845037_-	putative cytoplasmic protein	NA	NA	NA	NA
VEE29271.1\|1845379_1846834_-	AMP nucleosidase	NA	NA	NA	NA
VEE29274.1\|1846935_1848252_-	shikimate transporter	NA	NA	NA	NA
VEE29277.1\|1848566_1849619_+	ADP-heptose--LPS heptosyltransferase-like protein	NA	NA	NA	NA
VEE29280.1\|1849880_1851287_-	putative adhesin	NA	NA	NA	NA
VEE29283.1\|1851383_1856468_-	adhesin	NA	NA	NA	NA
VEE29286.1\|1856533_1856983_-	adhesin	NA	NA	NA	NA
VEE29289.1\|1856996_1857146_-	Uncharacterised protein	NA	NA	NA	NA
VEE29292.1\|1857600_1857993_-	Uncharacterised protein	NA	NA	NA	NA
VEE29295.1\|1857980_1858421_-	YD repeat-containing protein	NA	NA	NA	NA
VEE29298.1\|1858593_1858971_-\|transposase	IS1 transposase	U5P0U6	Shigella_phage	1.3e-67	100.0
VEE29301.1\|1859015_1859291_-\|transposase	IS1 transposase	NA	NA	NA	NA
VEE29304.1\|1860537_1861176_-\|integrase	phage integrase	A0A1B0VMI6	Pseudomonas_phage	1.1e-29	42.3
VEE29307.1\|1861269_1861800_-\|integrase	bacteriophage integrase	B7SYF8	Stenotrophomonas_phage	6.8e-30	42.7
1861963:1862042	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2420326 : 2543196

117

Escherichia_phage(37.5%)

integrase,lysis,coat,transposase,terminase,tRNA,tail

attL 2502533:2502548|attR 2548794:2548809

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE30884.1\|2420326_2421475_-\|transposase	transposase	A0A1W6JP07	Morganella_phage	1.2e-204	97.1
VEE30887.1\|2422066_2422735_-	putative lipoprotein	NA	NA	NA	NA
VEE30890.1\|2423037_2423631_-	tellurite resistance protein	NA	NA	NA	NA
VEE30893.1\|2423627_2424620_-	potassium-tellurite ethidium and proflavin transporter	NA	NA	NA	NA
VEE30896.1\|2424743_2425724_+	putative transferase	NA	NA	NA	NA
VEE30899.1\|2425715_2426255_-	ribosomal-protein-serine acetyltransferase	NA	NA	NA	NA
VEE30902.1\|2426317_2426542_-	protein	NA	NA	NA	NA
VEE30905.1\|2426681_2428301_-	glucans biosynthesis protein D	NA	NA	NA	NA
VEE30908.1\|2428561_2429905_-	putative cytoplasmic protein	NA	NA	NA	NA
VEE30911.1\|2430121_2431045_+	transcriptional regulator	NA	NA	NA	NA
VEE30913.1\|2431082_2432723_-	methyl-accepting chemotaxis protein III (ribose an galactose chemoreceptor protein)	NA	NA	NA	NA
VEE30916.1\|2434102_2434468_+	IS150 conserved protein InsB	A0A2I6AZV9	Macacine_betaherpesvirus	9.0e-66	100.0
VEE30919.1\|2434509_2434677_+	regulatory peptide	NA	NA	NA	NA
VEE30922.1\|2434788_2434962_-	Uncharacterised protein	A0A0R6PKG1	Moraxella_phage	4.4e-07	67.4
VEE30925.1\|2435206_2435737_-	cytochrome b561	A0A0U2QLA7	Escherichia_phage	3.1e-19	44.9
VEE30928.1\|2435925_2436042_+	glyceraldehyde-3-phosphate dehydrogenase C GapC	NA	NA	NA	NA
VEE30931.1\|2436300_2436927_+	glyceraldehyde-3-phosphate dehydrogenase C GapC	NA	NA	NA	NA
VEE30934.1\|2436968_2438408_-	aldehyde dehydrogenase A	NA	NA	NA	NA
VEE30937.1\|2438604_2439405_-	conserved SAM-binding protein, DUF218 family	NA	NA	NA	NA
VEE30940.1\|2439676_2443579_-	ATP-dependent helicase HrpA	A0A1V0SIV3	Klosneuvirus	2.2e-53	29.5
VEE30943.1\|2443779_2444385_+	FMN-dependent NADH-azoreductase	NA	NA	NA	NA
VEE30945.1\|2444435_2445752_-	Putative enzyme YnbD	NA	NA	NA	NA
VEE30948.1\|2445741_2447406_-	putative hydrolase	NA	NA	NA	NA
VEE30951.1\|2447576_2449883_-	protein involved in detoxification of methylglyoxal	NA	NA	NA	NA
VEE30954.1\|2449946_2450807_-	putative oxidoreductase	NA	NA	NA	NA
VEE30957.1\|2451038_2451629_-	phenylacetic acid degradation protein	NA	NA	NA	NA
VEE30960.1\|2451610_2452561_-	DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive	NA	NA	NA	NA
VEE30963.1\|2452661_2453975_-	phenylacetyl-CoA ligase	NA	NA	NA	NA
VEE30966.1\|2454001_2455207_-	beta-ketoadipyl CoA thiolase	NA	NA	NA	NA
VEE30969.1\|2455206_2455629_-	phenylacetate pathway hotdog-fold thioesterase	NA	NA	NA	NA
VEE30972.1\|2455618_2457001_-	3-hydroxyacyl-CoA dehydrogenase	NA	NA	NA	NA
VEE30975.1\|2457047_2457836_-	enoyl-CoA hydratase	NA	NA	NA	NA
VEE30978.1\|2457835_2458603_-	enoyl-CoA hydratase-isomerase	NA	NA	NA	NA
VEE30981.1\|2458599_2459670_-	subunit of the phenylacetly-CoA oxygenase/reductase	NA	NA	NA	NA
VEE30984.1\|2459677_2460175_-	Phenylacetic acid degradation protein paaD	NA	NA	NA	NA
VEE30987.1\|2460189_2460936_-	multicomponent oxygenase/reductase subunit for phenylacetic acid degradation	NA	NA	NA	NA
VEE30990.1\|2460944_2461232_-	phenylacetate-CoA oxygenase subunit PaaB	NA	NA	NA	NA
VEE30993.1\|2461243_2462173_-	phenylacetate-CoA oxygenase subunit PaaA	NA	NA	NA	NA
VEE30996.1\|2462457_2464503_+	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase	NA	NA	NA	NA
VEE30999.1\|2464750_2467024_+	tyramine oxidase	NA	NA	NA	NA
VEE31002.1\|2467081_2468581_-	phenylacetaldehyde dehydrogenase	NA	NA	NA	NA
VEE31005.1\|2468816_2469722_+	DNA-binding transcriptional activator FeaR	NA	NA	NA	NA
VEE31008.1\|2469893_2470220_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VEE31011.1\|2470227_2470413_-	lipoprotein	NA	NA	NA	NA
VEE31014.1\|2470409_2473049_-	protein	NA	NA	NA	NA
VEE31017.1\|2473256_2474246_+	D-lactate dehydrogenase	M1I4S0	Paramecium_bursaria_Chlorella_virus	1.5e-70	44.0
VEE31020.1\|2474356_2474779_+	heat-inducible protein	NA	NA	NA	NA
VEE31023.1\|2474775_2475042_-	protein	NA	NA	NA	NA
VEE31026.1\|2475315_2478840_+	pyruvate-flavodoxin oxidoreductase	NA	NA	NA	NA
VEE31029.1\|2479206_2480340_+	outer membrane protein N (porin)	Q1MVN1	Enterobacteria_phage	8.3e-118	58.8
VEE31032.1\|2480480_2480915_+	putative universal stress protein	A0A1W6JNV4	Morganella_phage	1.8e-28	52.8
VEE31035.1\|2481875_2482109_+	Qin prophage DNA-binding transcriptional regulator	A0A192Y6D5	Salmonella_phage	1.1e-32	88.3
VEE31038.1\|2482425_2483016_+	putative DNA-invertase	A0A0A7NPV4	Enterobacteria_phage	1.6e-24	38.8
VEE31042.1\|2483688_2486916_-\|tail	tail fiber protein	X2KTY7	Enterobacteria_phage	6.4e-06	58.8
VEE31045.1\|2486980_2487580_-	outer membrane precursor Lom	A5LH44	Enterobacteria_phage	3.5e-107	95.0
VEE31048.1\|2487647_2491127_-	Host specificity protein J of prophage	A5LH43	Enterobacteria_phage	0.0e+00	89.5
VEE31051.1\|2491187_2491730_-\|tail	putative phage tail component	A0A291AWV5	Escherichia_phage	5.4e-75	81.9
VEE31054.1\|2491726_2492326_-\|tail	tail component	A5LH41	Enterobacteria_phage	5.7e-118	97.5
VEE31057.1\|2492475_2493174_-\|tail	phage minor tail protein	A0A0K2FJ01	Enterobacteria_phage	1.1e-125	93.5
VEE31060.1\|2493173_2493470_-\|tail	putative phage minor tail protein	H6WZM2	Escherichia_phage	1.8e-24	52.0
VEE31063.1\|2493504_2496738_-\|tail	putative phage tail length tape measure protein	A0A2H4J9A1	uncultured_Caudovirales_phage	1.1e-111	34.5
VEE31066.1\|2497211_2497661_-	Uncharacterised protein	NA	NA	NA	NA
VEE31069.1\|2497721_2498684_-	Uncharacterised protein	A0A059VG08	Pseudomonas_phage	4.5e-56	39.2
VEE31072.1\|2498710_2499103_-	phage protein	NA	NA	NA	NA
VEE31075.1\|2499099_2499480_-	Uncharacterised protein	A0A059VF88	Pseudomonas_phage	1.1e-18	44.4
VEE31078.1\|2499480_2499864_-	Uncharacterised protein	A0A0P0I456	Acinetobacter_phage	2.2e-14	39.4
VEE31080.1\|2500138_2500258_-	Uncharacterised protein	NA	NA	NA	NA
VEE31083.1\|2500261_2500438_-	Uncharacterised protein	G8C7P8	Escherichia_phage	4.7e-12	62.3
VEE31086.1\|2500480_2501620_-\|coat	P22 coat protein - gene protein 5	G8C7P7	Escherichia_phage	3.7e-158	74.7
VEE31089.1\|2501718_2502483_-	Uncharacterised protein	G8C7P6	Escherichia_phage	6.9e-84	64.2
2502533:2502548	attL	NA	NA	NA	NA
VEE31092.1\|2502587_2503703_-	phage protein	I6PD76	Cronobacter_phage	2.4e-114	54.4
VEE31095.1\|2503683_2505090_-	Uncharacterised protein	G8C7P4	Escherichia_phage	3.0e-186	69.0
VEE31097.1\|2505092_2506394_-\|terminase	phage terminase	A0A1B1P9C9	Acinetobacter_phage	3.6e-149	59.6
VEE31100.1\|2506374_2507469_-\|terminase	terminase small subunit	A0A0U2RXW9	Escherichia_phage	2.9e-112	80.2
VEE31102.1\|2507472_2507682_-	Uncharacterised protein	NA	NA	NA	NA
VEE31105.1\|2507659_2508592_-	Uncharacterised protein	A0A1B1INP7	uncultured_Mediterranean_phage	1.4e-83	54.9
VEE31108.1\|2508584_2509376_-	ParB-like nuclease	R4TG31	Halovirus	2.8e-48	40.2
VEE31111.1\|2509513_2510938_-	Rac prophage; potassium transporter subunit	NA	NA	NA	NA
VEE31114.1\|2511108_2511573_-\|lysis	lysis protein	A0A0K2FJD0	Enterobacteria_phage	9.0e-71	92.1
VEE31117.1\|2511569_2512067_-	phage lysozome	M1FJA0	Enterobacteria_phage	3.2e-90	97.0
VEE31120.1\|2512066_2512282_-\|lysis	phage lysis protein	A5LH82	Enterobacteria_phage	1.3e-32	94.4
VEE31123.1\|2512533_2512929_-	tolA protein (fragment) of prophage	NA	NA	NA	NA
VEE31126.1\|2513079_2513508_-	TolA protein (fragment) of prophage	NA	NA	NA	NA
VEE31129.1\|2514552_2515095_-	antitermination protein	A0A0U2S606	Escherichia_phage	2.9e-76	75.7
VEE31132.1\|2515091_2515382_-	phage protein	A0A0U2KD41	Escherichia_phage	3.7e-46	87.5
VEE31135.1\|2515381_2515981_-	phage protein	A0A0U2RT94	Escherichia_phage	3.2e-105	91.5
VEE31138.1\|2516449_2516605_-	putative host cell-killing modulation protein	A0A0U2QV81	Escherichia_phage	1.9e-17	94.1
VEE31141.1\|2516676_2516964_-	toxin of the RelE-RelB toxin-antitoxin system	A0A2H4JBF4	uncultured_Caudovirales_phage	1.4e-29	66.0
VEE31144.1\|2516963_2517203_-	antitoxin of the RelE-RelB toxin-antitoxin system and transcriptional repressor of relBEF	A0A2H4JBG1	uncultured_Caudovirales_phage	1.6e-18	54.4
VEE31147.1\|2517735_2518068_+	Qin prophage protein	NA	NA	NA	NA
VEE31149.1\|2518504_2519845_-\|integrase,transposase	putative integrase/transposase	NA	NA	NA	NA
VEE31152.1\|2520641_2521841_+	inner membrane transport protein YdhP	NA	NA	NA	NA
VEE31154.1\|2521852_2522545_+	cation transport protein chaC	NA	NA	NA	NA
VEE31156.1\|2522541_2523423_+	transcriptional regulator	NA	NA	NA	NA
VEE31159.1\|2523553_2524831_-	Predicted membrane protein (DUF2254)	NA	NA	NA	NA
VEE31161.1\|2524894_2526892_-	secondary glycine betaine transporter	A0A2I7QNT1	Vibrio_phage	3.3e-21	26.2
VEE31163.1\|2527232_2527655_-	putative prophage protein	A0A0U2QQN3	Escherichia_phage	4.8e-63	88.5
VEE31165.1\|2527695_2528766_-	replication protein	A0A088CD36	Shigella_phage	4.7e-62	64.6
VEE31168.1\|2528837_2529263_-	phage regulatory protein	NA	NA	NA	NA
VEE31171.1\|2529246_2529528_-	putative antirepressor protein Cro	K7PHA1	Enterobacteria_phage	8.5e-24	72.6
VEE31175.1\|2529628_2530048_+	putative phage repressor protein CI	K7PK07	Enterobacteria_phage	8.8e-25	65.1
VEE31178.1\|2530302_2530437_+	Rac prophage protein	NA	NA	NA	NA
VEE31181.1\|2530447_2530603_+	Rac prophage; predicted protein	M4QQ57	Salicola_phage	6.1e-08	55.3
VEE31184.1\|2530599_2531211_-	prophage CP-933R superinfection exclusion protein	NA	NA	NA	NA
VEE31187.1\|2531529_2531751_+	FtsZ inhibitor protein	A0A0U2RTC4	Escherichia_phage	2.0e-36	98.6
VEE31190.1\|2531750_2531921_+	Rac prophage; zinc-binding protein	A0A0U2SHB5	Escherichia_phage	3.6e-17	71.4
VEE31193.1\|2531995_2532271_+	putative bacteriophage protein	A0A0U2QW85	Escherichia_phage	1.4e-42	96.7
VEE31196.1\|2532372_2534973_+	exonuclease VIII	A0A0U2I1R6	Escherichia_phage	3.9e-248	63.5
VEE31199.1\|2534965_2535775_+	recombination and repair protein RecT	A0A1P8DTF2	Proteus_phage	3.4e-105	71.1
VEE31202.1\|2536018_2536228_+	gydaC	A0A0U2QL97	Escherichia_phage	6.1e-27	98.4
VEE31205.1\|2536306_2536522_+	excisionase	A0A0U2RY08	Escherichia_phage	1.8e-37	100.0
VEE31208.1\|2536523_2537759_+\|integrase	phage integrase	A0A0U2JGI6	Escherichia_phage	5.5e-240	98.8
VEE31211.1\|2537810_2538746_+\|tRNA	C32 tRNA thiolase	A0A0U2S5Z2	Escherichia_phage	5.9e-146	98.8
VEE31214.1\|2538874_2540248_-	ATP-independent RNA helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	6.6e-53	33.1
VEE31217.1\|2540277_2540451_-	Uncharacterised protein	NA	NA	NA	NA
VEE31220.1\|2540725_2541709_-	zinc transport protein	NA	NA	NA	NA
VEE31223.1\|2541963_2543196_+	putative signaling protein	A0A127AWB9	Bacillus_phage	3.1e-17	39.5
2548794:2548809	attR	NA	NA	NA	NA

DBSCAN-SWA_7

3117841 : 3164754

Enterobacteria_phage(57.41%)

integrase,capsid,lysis,coat,transposase,terminase,portal,head,tail

attL 3138301:3138316|attR 3166462:3166477

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE32664.1\|3117841_3119698_-\|tail	tail fiber protein	X2KTY7	Enterobacteria_phage	1.4e-05	61.2
VEE32666.1\|3119834_3120572_+	Uncharacterised protein	NA	NA	NA	NA
VEE32668.1\|3121133_3121733_-	outer membrane precursor Lom	A0A0P0ZCF6	Stx2-converting_phage	3.7e-109	98.5
VEE32670.1\|3121799_3125198_-	Host specificity protein J	K7PKJ2	Enterobacteria_phage	0.0e+00	90.7
VEE32672.1\|3125258_3125831_-\|tail	phage tail assembly protein	A0A2R9YJH6	Escherichia_phage	1.5e-83	98.9
VEE32674.1\|3125827_3126571_-\|tail	putative tail fiber component K of prophage	K7PLW1	Enterobacteria_phage	5.9e-149	97.6
VEE32676.1\|3126576_3127275_-\|tail	phage minor tail protein	A0A0K2FJ01	Enterobacteria_phage	2.3e-134	100.0
VEE32678.1\|3127274_3127604_-\|tail	Minor tail protein M	A0A0K2FIE9	Enterobacteria_phage	9.6e-59	100.0
VEE32680.1\|3127600_3130162_-\|tail	tail component of prophage	A0A0K2FI43	Enterobacteria_phage	0.0e+00	91.9
VEE32682.1\|3130154_3130589_-\|tail	minor tail protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
VEE32684.1\|3130570_3130993_-\|tail	phage minor tail protein	A0A0K2FIQ8	Enterobacteria_phage	6.7e-73	100.0
VEE32686.1\|3131008_3131749_-\|tail	Major tail protein V	A0A2I6TC77	Escherichia_phage	4.3e-131	98.4
VEE32688.1\|3131756_3132152_-\|tail	phage minor tail protein	A0A2R9YJI2	Escherichia_phage	5.5e-69	97.7
VEE32690.1\|3132148_3132727_-\|tail	minor tail protein	A0A2R9YJK4	Escherichia_phage	6.6e-79	98.4
VEE32692.1\|3132738_3133092_-\|capsid	minor capsid protein	A0A0K2FJB7	Enterobacteria_phage	2.0e-62	100.0
VEE32694.1\|3133103_3133502_-	phage DNA packaging protein	A0A0K2FIR1	Enterobacteria_phage	3.1e-64	100.0
VEE32696.1\|3133543_3134569_-\|head,coat	phage major head protein (major coat protein)	C6ZCY2	Enterobacteria_phage	1.0e-191	99.4
VEE32698.1\|3134624_3134957_-	Head decoration protein from bacteriophage origin	C6ZCY1	Enterobacteria_phage	2.2e-55	100.0
VEE32700.1\|3134966_3136286_-\|capsid	minor capsid protein C from bacteriophage origin	A0A2I6TC87	Escherichia_phage	6.9e-233	98.2
VEE32702.1\|3136266_3137868_-\|capsid,portal	phage portal protein (minor capsid protein)	A0A0K2FJC0	Enterobacteria_phage	3.6e-308	98.7
VEE32704.1\|3137864_3138071_-\|head,tail	head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
VEE32706.1\|3138067_3139993_-\|terminase	phage terminase large subunit	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.7
3138301:3138316	attL	NA	NA	NA	NA
VEE32708.1\|3139967_3140513_-	prophage qsr' DNA packaging protein NU1-like protein	A0A0K2FIG2	Enterobacteria_phage	4.7e-95	99.4
VEE32710.1\|3141193_3141604_+	Qin prophage	C6ZCX4	Enterobacteria_phage	2.7e-55	77.8
VEE32712.1\|3141906_3142431_-	Rha protein	G8C7W4	Escherichia_phage	4.5e-87	94.2
VEE32714.1\|3142633_3142786_-	bacteriophage protein (Gene 65)	Q716B2	Shigella_phage	6.2e-21	98.0
VEE32716.1\|3142773_3143253_-	Rz endopeptidase from lambdoid prophage DLP12	Q9AZ06	Salmonella_phage	2.4e-71	92.3
VEE32718.1\|3143237_3143735_-	phage lysozome	A0A1B5FP97	Escherichia_phage	4.2e-90	97.6
VEE32720.1\|3143734_3143950_-\|lysis	phage lysis protein	A5LH82	Enterobacteria_phage	1.2e-33	98.6
VEE32722.1\|3144391_3144868_-	araC-type regulatory protein from bacteriophage origin	NA	NA	NA	NA
VEE32724.1\|3145021_3145183_-	Uncharacterised protein	NA	NA	NA	NA
VEE32726.1\|3145219_3146179_-	putative pathogenicity island protein	NA	NA	NA	NA
VEE32728.1\|3146371_3146704_+	lipoprotein	A0A1W6JNX6	Morganella_phage	8.2e-26	55.7
VEE32730.1\|3146714_3147092_-\|transposase	IS1 transposase	Q71TF0	Escherichia_phage	1.3e-67	100.0
VEE32732.1\|3147136_3147412_-\|transposase	IS1 transposase	NA	NA	NA	NA
VEE32734.1\|3147565_3148516_-	magnesium and cobalt transport protein CorA	NA	NA	NA	NA
VEE32736.1\|3148885_3149200_+	protein	NA	NA	NA	NA
VEE32738.1\|3149228_3149504_+\|transposase	IS1 transposase	NA	NA	NA	NA
VEE32740.1\|3149548_3149926_+\|transposase	IS1 transposase	Q71TF0	Escherichia_phage	1.3e-67	100.0
VEE32742.1\|3150301_3150679_-	putative antitermination protein Q-like protein; DLP12 prophage	Q777W5	Enterobacteria_phage	2.1e-54	84.2
VEE32744.1\|3150901_3151264_-	endodeoxyribonuclease RUS	K7PM48	Enterobacteria_phage	2.5e-60	97.4
VEE32746.1\|3151260_3151551_-	DLP12 prophage	K7PGZ6	Enterobacteria_phage	4.3e-47	94.8
VEE32748.1\|3151543_3151714_-	prophage protein NinE	K7P7K0	Enterobacteria_phage	1.5e-12	67.9
VEE32750.1\|3151713_3152169_-	DLP12 prophage; DNA base-flipping protein	I6PD71	Cronobacter_phage	3.7e-61	68.2
VEE32752.1\|3152375_3152576_-	Uncharacterised protein	NA	NA	NA	NA
VEE32754.1\|3153205_3153700_-	Uncharacterised protein	NA	NA	NA	NA
VEE32756.1\|3153846_3154020_-	Ren protein from phage origin	M1FPD5	Enterobacteria_phage	2.3e-19	85.5
VEE32758.1\|3154016_3154718_-	replication protein P of bacteriophage	M1FJ72	Enterobacteria_phage	4.6e-127	97.4
VEE32760.1\|3154714_3155644_-	replication protein O	K7P7F0	Enterobacteria_phage	1.0e-110	68.3
VEE32762.1\|3155730_3156270_-	bacteriophage regulatory protein CII	M9NZI6	Enterobacteria_phage	3.4e-61	66.1
VEE32764.1\|3156339_3156570_-	Cro	A0A2H4FNF3	Salmonella_phage	1.5e-21	68.0
VEE32766.1\|3156608_3157364_+	Regulatory protein CI from bacteriophage origin	Q76H56	Enterobacteria_phage	1.4e-92	75.0
VEE32768.1\|3157443_3158289_+	Protein rexA	M1FPD4	Enterobacteria_phage	1.9e-63	47.7
VEE32770.1\|3158303_3158747_+	Uncharacterised protein	M1FPN8	Enterobacteria_phage	6.7e-31	49.3
VEE32772.1\|3159223_3159430_+	prophage Kil protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
VEE32774.1\|3159505_3159802_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	3.6e-49	99.0
VEE32776.1\|3159807_3160593_+	bacteriophage recombination protein	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
VEE32778.1\|3160589_3161270_+	exonuclease	A0A0N6WET1	Escherichia_phage	1.3e-131	98.7
VEE32780.1\|3161266_3161449_+	phage protein	A0A0N7CHV0	Escherichia_phage	1.3e-28	98.3
VEE32782.1\|3161421_3161613_+	phage protein	A0A0P0ZC67	Stx2-converting_phage	7.3e-27	100.0
VEE32784.1\|3161689_3161905_+	ybl17	A0A1I9LJM7	Stx_converting_phage	1.0e-32	100.0
VEE32786.1\|3162003_3162225_+	putative C4-type zinc finger protein	A0A0K2FI84	Escherichia_phage	2.9e-35	100.0
VEE32788.1\|3162435_3162585_-	putative transmembrane protein	NA	NA	NA	NA
VEE32790.1\|3163280_3163448_+	Uncharacterised protein	A5VWB7	Enterobacteria_phage	2.9e-27	98.2
VEE32792.1\|3163683_3164754_+\|integrase	putative integrase	K7P6P6	Enterobacteria_phage	3.9e-202	100.0
3166462:3166477	attR	NA	NA	NA	NA

DBSCAN-SWA_8

4064323 : 4085604

Stx2-converting_phage(33.33%)

integrase,transposase

attL 4084162:4084206|attR 4094557:4094601

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
VEE34401.1\|4064323_4064704_+\|transposase	transposase	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
VEE34403.1\|4064700_4065048_+	prophage CP-933O IS protein	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
VEE34405.1\|4065097_4066483_+\|transposase	transposase	A0A0P0ZBS5	Stx2-converting_phage	2.8e-253	87.5
VEE34407.1\|4066721_4068080_-	Uncharacterized protein conserved in bacteria	NA	NA	NA	NA
VEE34409.1\|4068830_4069088_-	Biofilm development protein YmgB/AriR	NA	NA	NA	NA
VEE34411.1\|4069211_4069322_+	Uncharacterised protein	NA	NA	NA	NA
VEE34413.1\|4069849_4070059_-\|transposase	IS1 transposase	NA	NA	NA	NA
VEE34415.1\|4070838_4071360_+	RNA polymerase sigma factor	NA	NA	NA	NA
VEE34417.1\|4071356_4072310_+	iron(III) dicitrate sensor protein	NA	NA	NA	NA
VEE34419.1\|4072396_4074721_+	iron(III) dicitrate TonB-dependent receptor	NA	NA	NA	NA
VEE34421.1\|4074765_4075668_+	iron-dicitrate transporter substrate-binding subunit	NA	NA	NA	NA
VEE34423.1\|4075664_4076663_+	iron(III) dicitrate transport system, permease protein	NA	NA	NA	NA
VEE34425.1\|4076659_4077616_+	iron-dicitrate transporter subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	26.1
VEE34427.1\|4077616_4078384_+	iron(III) dicitrate transport system, ATP-binding protein	G3M9Y6	Bacillus_virus	6.4e-13	24.8
VEE34429.1\|4078922_4079198_-	KpLE2 phage-like element	NA	NA	NA	NA
VEE34431.1\|4079848_4081372_-	reverse transcriptase-like protein from prophage or plasmid	A0A0U4J920	Pseudomonas_phage	3.7e-44	31.8
VEE34433.1\|4081963_4082203_-	IS911 orfA	Q716C2	Shigella_phage	1.5e-29	100.0
VEE34435.1\|4082415_4082715_-\|transposase	transposase Orf1 of IS3 family IS element	Q716C1	Shigella_phage	3.9e-43	98.0
VEE34437.1\|4083689_4083965_-\|integrase	phage integrase	Q7M297	Enterobacteria_phage	5.1e-21	51.1
4084162:4084206	attL	NA	NA	NA	NA
VEE34439.1\|4084326_4085604_+\|integrase	integrase	NA	NA	NA	NA
VEE34439.1\|4084326_4085604_+\|integrase	integrase	NA	NA	NA	NA
4094557:4094601	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LR134295

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection