CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
LT985475	Listeria monocytogenes isolate JF5861 complete genome genome assembly, chromosome: 1	2 crisprs	DinG,cas3,WYL,casR,DEDDh,RT,csa3	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: LT985475_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LT985475_1

501261-501845

Orphan

Consensus_repeat	Method
GATGTAAGTAATTTTGATACNAGTTCAGTAACTNATATG	CRT

7 spacers

The CRISPR arrays of LT985475_1

>merge|LT985475|1|501261-501845|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATGTGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTGGATGTAAGTCATTTTGATACGAGTTCAGTAACTAATATGTCTTACATGTTTTATGATAATAGAAACCTTGAGGTGCTGGATGTAAGCAACCTTGATACCGGTTCAGTAACTAATATGTATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTGGATGTAAGTAATTTTGATACGAGTTCAGTAACTGATATGTATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTAGATGTAAGTAATTTCGATACCAGTTCCGCTACTGCAATGGTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTGGATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATGCGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGCGTTAGATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATGGCTGCCATGTTTTCTGATAATGAAAAACTGGAGAAGCTTGATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

>LT985475|1|1|501261-501845|CRT
GATTTGAGTGGTCTTGATACTAGTGCGGTAACTACTATG	TGGGATATGTTTAACAGCTGTAGGGCACTTGAGGAACTG
GATGTAAGTCATTTTGATACGAGTTCAGTAACTAATATG	TCTTACATGTTTTATGATAATAGAAACCTTGAGGTGCTG
GATGTAAGCAACCTTGATACCGGTTCAGTAACTAATATG	TATGCCATGTTTGAAGATTGTACTAGTCTTGAAGAGCTG
GATGTAAGTAATTTTGATACGAGTTCAGTAACTGATATG	TATAGAGTGTTTAATGGCTGTGAAAAACTGAAGAAACTA
GATGTAAGTAATTTCGATACCAGTTCCGCTACTGCAATG	GTTCAAATGTTTAGAAATTGTAGCGCCCTTGAGAAGTTG
GATGTAAGTAATTTTAATACGAGCTTAGTAACTGATATG	CGTGCCATGTTTGCTGGTTGTACTAGTCTTGAAGCGTTA
GATGTAAGTAATTTTGATACGAGTTCAGTAACTAATATG	GCTGCCATGTTTTCTGATAATGAAAAACTGGAGAAGCTT
GATTTAAGTACCTTTGATACCAGTTCAGTGACTAACATG

Protein	Signature genes	Signature genes Name	Protein_function
LT985475.1\|SPE83343.1\|507947_508295_+\|hypothetical-protein	unknown	unknown	unknown
LT985475.1\|SPE83335.1\|505126_505612_+\|hypothetical-protein	unknown	unknown	unknown
LT985475.1\|SPE83315.1\|485881_488041_-\|transglutaminase	unknown	unknown	gnl\|CDD\|376628
LT985475.1\|SPE83313.1\|485009_485765_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379782
LT985475.1\|SPE83347.1\|509023_510004_-\|oxetanocin-A-resistance-protein-OxrB	unknown	unknown	gnl\|CDD\|224004
LT985475.1\|SPE83333.1\|504633_505107_+\|hypothetical-protein	unknown	unknown	unknown
LT985475.1\|SPE83322.1\|492022_493306_+\|permease	unknown	unknown	gnl\|CDD\|271377
LT985475.1\|SPE83338.1\|506020_506287_+\|transposase	unknown	unknown	unknown
LT985475.1\|SPE83340.1\|506793_506970_+\|hypothetical-protein	unknown	unknown	unknown
LT985475.1\|SPE83336.1\|505639_505945_+\|cell-wall-surface-anchor-protein	unknown	unknown	gnl\|CDD\|273478
LT985475.1\|SPE83328.1\|496585_498124_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|368260
LT985475.1\|SPE83345.1\|508698_508941_+\|hypothetical-protein	unknown	unknown	unknown
LT985475.1\|SPE83324.1\|493306_494407_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226065
LT985475.1\|SPE83326.1\|494399_495950_+\|hydantoinase	unknown	unknown	gnl\|CDD\|223223
LT985475.1\|SPE83332.1\|502807_504568_+\|membrane-associated-lipoprotein	unknown	unknown	gnl\|CDD\|308794
LT985475.1\|SPE83319.1\|489190_490138_-\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
LT985475.1\|SPE83342.1\|507020_507638_+\|hypothetical-protein	unknown	unknown	unknown
LT985475.1\|SPE83330.1\|498386_500468_+\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
LT985475.1\|SPE83317.1\|488037_489186_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224635
LT985475.1\|SPE83321.1\|490293_491889_+\|PucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225306

Protein	Function_ID	Function_description	E-value
LT985475.1\|SPE83315.1\|485881_488041_-\|transglutaminase	gnl\|CDD\|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	4.40206e-28
LT985475.1\|SPE83313.1\|485009_485765_-\|hypothetical-protein	gnl\|CDD\|379782	pfam16160, DUF4866, Domain of unknown function (DUF4866). This family consists of uncharacterized proteins around 250 residues in length and is mainly found in various human gut Firmicute species and abundant in human gut metagenomic datasets. The function of this family is unknown.	2.71521e-121
LT985475.1\|SPE83322.1\|492022_493306_+\|permease	gnl\|CDD\|271377	cd11484, SLC-NCS1sbd_CobB-like, nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain. This NCS1 subfamily includes Escherichia coli CodB (cytosine permease), and the Saccharomyces cerevisiae transporters: Fcy21p (Purine-cytosine permease), and vitamin B6 transporter Tpn1. NCS1s are essential components of salvage pathways for nucleobases and related metabolites; their known substrates include allantoin, uracil, thiamine, and nicotinamide riboside. NCS1s belong to a superfamily which also contains the solute carrier 5 family sodium/glucose transporters (SLC5s), and solute carrier 6 family neurotransmitter transporters (SLC6s).	1.15029e-95
LT985475.1\|SPE83336.1\|505639_505945_+\|cell-wall-surface-anchor-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	4.51255e-05
LT985475.1\|SPE83328.1\|496585_498124_+\|transcriptional-regulator	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	1.06475e-18
LT985475.1\|SPE83324.1\|493306_494407_+\|hypothetical-protein	gnl\|CDD\|226065	COG3535, COG3535, Uncharacterized conserved protein [Function unknown].	0
LT985475.1\|SPE83326.1\|494399_495950_+\|hydantoinase	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.15698e-106
LT985475.1\|SPE83332.1\|502807_504568_+\|membrane-associated-lipoprotein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.35905e-28
LT985475.1\|SPE83319.1\|489190_490138_-\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.47241e-102
LT985475.1\|SPE83347.1\|509023_510004_-\|oxetanocin-A-resistance-protein-OxrB	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	5.46999e-45
LT985475.1\|SPE83330.1\|498386_500468_+\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	5.28459e-29
LT985475.1\|SPE83317.1\|488037_489186_-\|hypothetical-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	7.03616e-53
LT985475.1\|SPE83321.1\|490293_491889_+\|PucR-family-transcriptional-regulator	gnl\|CDD\|225306	COG2508, COG2508, Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism].	2.42853e-59

>LT985475.1|SPE83330.1|498386_500468_+|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIALGNANVSIAQERDTTNKLPEEELGSLDTSNLIAEEVAQDKPAEVENLEEIPTTDELMQNPDVREQSVADSDDPDLTAVSSGDYWTIYYNSANDEYSLRMFGNVPSSKPSAWNSYLKYIKHIEIEEATLTGDFSSYFRSNVFTVLESVRIERSNLSGVTSFARAFEGDSESESPLEKVIIRDNYYPETPSLTNISRMFTLCRKLSELDVSGLNTSSVTKMDTIFSNANSLKELDVSHFDTSSVTDMSSMFAACNSLEELDVSNFDTSSVTNMKYMLSGLHLKKLDVSNFDTSSVTNMYGMFAYCYNLEELDVSNFDTSSVNNMLHMFYVCNNLEELDLSNFDTSSVTNMFAMFAYCTSLKEIDVSNFDTSSVTTMSAMFFECSSLEALDLSNFDTSSVTTMASMFENSTALKSLYLDNFTDAASMTDMFKGTTSLTYLFVSHNLSTFNRLENTSWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQNKVSGEYWEEIVPVKEDYYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWVENYTVIIPASISLNEATELKVEGINRGSKALSVGLNRLATSVSESNELTLANTADTTVQCSAPLSWDGSENNPEKAILTLAPGSEITEGDAVMAIEAPENIQAGKYTGNLVFSINYE
>LT985475.1|SPE83328.1|496585_498124_+|transcriptional-regulator
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLASFPNLQALAKKVHVSYSGIKKEIKELNEELSERNLYISTGNQVEITGDEFSLRIFYAFLFLVAYSGDRWPFSFVRYDEITDLLESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASERVNDNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTDLDRNIRKIHKVNHLEPLISQLVNLKEMDPLKPFEERLTSDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEIINQVDPVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKD
>LT985475.1|SPE83326.1|494399_495950_+|hydantoinase
MYKIGIDVGGTNTDAVILDENQQLIHSVKMPTSEDIETGITESLHRVLSETGIDRSKVTHAMLGTTQCTNAIVERKKLAKVGVLRLGYPATASVLPYTAWPEDMVGFLSGKYKLTGGGYEYDGQVLSEINEAEIRETLASWKGEVESVAVVGVFSSLKNDQELAVQKIIEEELGADIPVSISSSVGSVGLIERENATILNAALFKVIAATSDGFEKALEQEGIAHAEIYLCQNDGTLMSLNYARQFPILTIACGPTNSIRGASYLAGLKDAMVLDVGGTTSDIGVLTDGFPRESSLAVDVGGVRTNFRMPDIISIGLGGGSIVREKDGDITIGPDSVGYRISEEALVFGGKTMTTTDIAVRLGRAEIGNPELVAHIPTDFAEKAYKKIAEMTEDAIDKMKTSSGSVSLVLVGGGSVIIPDEISGVAQIFRDKNGPVANAIGASISQISGQYEQIYIYSQIEREEALQDAEQKAREQATLAGAVTDSIEVVEVEEIPLAYHPGNATRLRVKVVGNLV
>LT985475.1|SPE83324.1|493306_494407_+|hypothetical-protein
MRYLDEQAIENIAIGAAFLGTGGGGDPYIGKMMALTAIKKHGPIKLLSPEEIADDDYFIPAAMMGAPSVLIEKFPKGDEFVRVFEKLGRYVGKEVKGTFPMEAGGVNSMIPIVVAAQLGLPMVDCDGMGRAFPELQMVTFHLDGISATPMAITDEKGNIGIMETIDNKWTERLARVTTVEMGASSLVSLYPCNGAQIKQSSIKNIVTLSEEIGKVIRETSMDEAEKLQKLLDVTHGYHLFEGKITDVVRETRAGFNFGRVKIDGLNKDTGSEVIVHFQNENLVAEKNGEPIAITPDLICMVDLETLMPVTTEALKYGKRVRVMALPADDAWRTDKGIETVGPRYFGYDVDFEPLEELVKKEERRHV
>LT985475.1|SPE83322.1|492022_493306_+|permease
MTEKKSVEQTQSWQSLAFVWTGAMICVPSLLVGGTLISGMPLWEAILIALLGYGVIVLFMIYQGMQSSDLGIPAVSVASQVFGEQGSKKIISILLAIACLGWFGIQANVCGAAFSQFLGIYGINLPVPVSSLIWGVIMLLSAIYGIRILSILNYIAVPVLLFVCIYGLVVSLNDGGLAIVENYKPAGSMSFMTGLAITIGSFALGAVIAGDYSQYTKSRKDVVKAAIVGILPSGVLMITVGAVLALTAGTADISVVFTNLGLPVLGIIGLILAAWTTNAVNAFSGGIAIINVFNISEKYHKVAVAVAGGLGTILAVIGILNHFVPIMSVLSAMVPPVAGVMIASYWIVQKGDKSKWAPVSGVNWLGVSSWLVGAVIAGIPVILTFFPELPQLPNQPLIGIILSLAVYLIGAKVLSGKTNNVENLEGK
>LT985475.1|SPE83321.1|490293_491889_+|PucR-family-transcriptional-regulator
MSVKLADLMKLPSLKEAKVVSGKSGLSKLVSSISVLEYTEVALLEDDLFDNDEFYGSEIVVSAFVNIRDDVEAQCRTIERLHKVGEVALILYYVGIFVPKMDQKLIDFANELDFTIIVMPENEMSLRYSEVIYEVVEAIVKQEMTDTNFVTESLEQISSVRPPQRNIDTTLKILSDRTHTSLVLTDNSFQVINSITWPRTRHWDFERIIEASKQIGEHELVQLTLDERDFYTARKPIFQDGMQAMHLFMMKEKGVLTADVVMQITEVVQVFMNLWGRNYVEISTAELMKAILNDESVKMRRLGKILNVDVSSIKWMWLVKTEEIRDNEQVLAELKSFVASHFQVSLIDLFEDNIVVLLDNSVAQRDRTHTANEFAMMMKEHGIDLKITVCQGMEQTSDVQSAYSLVNEYKNAANAIYANKSIYSLQEIDFAAKCVEIVDRGELAIAEQMRPLKPLEDNDELIETLSVFLLEGESNYNQAAELLFLHKNTIKYRIQRINELLQYPATKIPESYNLYLAVAIRRILGGNNNNK
>LT985475.1|SPE83319.1|489190_490138_-|MoxR-family-ATPase
MSIEPSIKIEEIINEVEKVIVGKRHVVKLSLTALLAGGHVLLEDVPGVGKTMMVRTLSKTIGVSFKRIQFTPDLLPADVTGVSIFNPETRDFEFRPGPVMGNIVLADEINRTAPRTQAALLEGMAENSVTVDGITRKLANPFFVMATQNPIEYEGTYALPEAQLDRFLLKINIGYPTVEEEMQLLTLKQYQDPLDQTQQVVTLSELLDLKNKAKQVFIDDVLKNYIIRLVDATRKHPSVALGISPRGSLAFMQAAQAFALIEGRDYVIPDDIQYLAPYIFTHRLILKSEAYYNEETAESIIASILKNTSVPVEKR
>LT985475.1|SPE83317.1|488037_489186_-|hypothetical-protein
MLKKRLLLAFRWIIMLIIYAGLWTYTLFQGDTASWFLTYFFSFILLLLFLSSIYPLKAWKVNRRFVKNTYHDGDLVDMQVSFTRKSRYPVGYLLFQQKIPASFGNVSARQQVVYPLFKKHFTVTLAGFVGVRGIHSFPPVDVETSDAFGLLERSRQLSSEKSLTIYPTYFPDVLEKISEASPENERNAAYWTLKKNSNLHSLREFSSGDRISLIDWKSSAKSDQLMTREFENSATSRLSVIFYGASHPNFELSLRAAYSFIRKISEDNGEIRVTLLGDQTSKFAPAKGTSRLQDISTAFAEIAPVDSLTLQESLDSNLHSGEKILLFTPCIDTMLMQKVTRLTDNKQLQIITFQSEHSKAMDAPAIFLEPASLLSRWEREAK
>LT985475.1|SPE83315.1|485881_488041_-|transglutaminase
MKRYLTLVMLFILSVLLISEWIYPFAELTELSTANWIILFITLSLGSFFLRLKYYWTIPLHIVMIIFVSGIYYAKGGILAGNWFVSFFQITFNGFRDMVQFRSSDISMDFILIVFLIALWLLSYITTYSILRKQRVMSVLVLTVAYLAVINTFTDYNSNWAIVRTVLEGFLLLHLALASRIAAPNRISADSLKRNGLFYHIFVILLLAVFVFSSLMLPKKAPIFPDPVPTIKNALGINTTRTVGYSEDDTTLGGALKKDNATVFTARAEKGHYWRVESKTVYTGTGWANANSADVISFSSGDNFPIQLTEQTTGATNTAEISFASSNDYMPYPYGTQTVNGAVDSFSANLTIERVGPVDTIKNYTVQLKTPVYNIEKMQNADFSTLSNAFVSQYTQTPKDLPDRVTKLANKVTKDADSIYDKTKAIERYLSASGTFTYSTEDAKETPRGADYVDQFLFETQIGYCDNFSTSMVVMLRSLGIPARWAKGYTPGEGEKKENDAKTTYTITNNNAHSWPEVFFPGTGWVPFEPTATFSNPENFQEPTTETANKPETPNDSTSTPETPNTADKTPEQDNGSSSTGETPKKEEPKTETAASNFEIPSWVWWIPAGLVVTLLALAIIFRRRIRRYLLLRSLRNSPEFGKTYHRLMKLLASYGYVRESSETLRHFSTRVDAELTTTEFSRLTKMYEAQIYSNNLTEKVITAEETQLVQQVIARLTK
>LT985475.1|SPE83313.1|485009_485765_-|hypothetical-protein
MTTIFPKEQNVAPLFEQILANPTACRRFKDVFLDNLESYQETRGFEKDDTLFAKIILSAYRQSDVSALLLGVCGRTLFELLRQAFLIPKKLTVDNPFFLTDKEGNFIAKKDDISNREQEKFQEIYQSDLHHSETTIFLVDDDDIIHSYEPDFSISTKRINKKRGILVLYSLPDTLKLGMTESEVYAFIWKTFLHIQEIIPSSRIFYGQETSENADELGVFLPIHHFEKKMLQNIEQVNELVDALREQMVNK
>LT985475.1|SPE83332.1|502807_504568_+|membrane-associated-lipoprotein
MKKFSMRVVLIISVLFIAFGSANVSIAQERDTTNKLPEEELGSLDTSNIIAEEVAQEKPAEVEQLEEIPTTDELMQNPDVLEKSVADSDDPDLTVVSSGDFWTIYRNTVNNEYNLRMFGNVPSSRPTAWNSYLKSIKHIEIEEATLTGSFASYFRGTDFPVLESVRIEQCNLSGVTSFEMAFYNSGIEKVIIRDNDYPKAPSLLTATQYMFSLCRNLSELDLSGLDTSAVTNMYAMFQNCTSLEELDLSNFDTSSATNMYSMFSGCRSLEKLDVSNFDTSSVAHMQFMFEKCSILEELDLSNFDTSSVTNMSYMFQLCPALKSLYLDNFTDAAIMTGMFAGTTSLTYLFVSHNLSTFNNLENTSWYDEKNWVQFSNLSQLQTYHRQQSEPIGYRKGAFLSLTMDAMGGEFEDAEEQKVQSKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWIENYTVIIPASISLNETSELKVEGINRGDKNLSVGLNRTATSISESNKLTLSNTADATVQCLVPLSWDGSENNPENAILTLAPGSEITEGDAVMEIKSPENIQAGKYTGNVVFSIKYD
>LT985475.1|SPE83333.1|504633_505107_+|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKVTLYANETTQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>LT985475.1|SPE83335.1|505126_505612_+|hypothetical-protein
MNKLVLSTLSVAAMGMVFFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>LT985475.1|SPE83336.1|505639_505945_+|cell-wall-surface-anchor-protein
MKRKLVLAMVLISFCGMFLLSPERVQASQTVVEVFISEDDLDVSEENIQEIPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRKRKKKE
>LT985475.1|SPE83338.1|506020_506287_+|transposase
MARIEYGEEIQKSLLVLYSRGSTIQSICKEYGIPRYEFHKWMKLHDADKLETKEVKTFLQIRELKQQKNKLEEEILFLNEAINLLESP
>LT985475.1|SPE83340.1|506793_506970_+|hypothetical-protein
MKKIIIGVFFGILILVIVGLYVSYVYMNQSFIWVAGILLLLGTLFNWFLYNKYLSKKT
>LT985475.1|SPE83342.1|507020_507638_+|hypothetical-protein
MLMSLSVLPLATYASETENTPTESYDGENFIATQTGNTLVIEDKKTGETVKIEMNDEENGVITSDDGTIENVHRDEEGNVYVDNELELEAPPLDIEDGINIATQPRLLKASKWIYVQTTKYNTTTQGNMRSLALGILSFMPITGPIFGIVAIIDAARSMGAKTLYVRVKQYRTSGYQFYKYDSYYYANASLTKLVKKTSQTKRMW
>LT985475.1|SPE83343.1|507947_508295_+|hypothetical-protein
MQKDTYSGIRLSVIQLIDSKKENLKENNIKLTIIKDEKDGYVVELDNDKCMAEIVVEEPTYAPYRYISFEVVSLMDGKVKIIYSWYDDETSQWSDIEKELNKGIQFLNNFKTMEQ
>LT985475.1|SPE83345.1|508698_508941_+|hypothetical-protein
MKRIILTSTLIVWTIVCIYMSISMVSNNTGIAFPIWLHIILLICFLATGIVNVKKKEYLWSTMLFEGVLVVLLSLIIVLV
>LT985475.1|SPE83347.1|509023_510004_-|oxetanocin-A-resistance-protein-OxrB
MMKITDPLYGTFEIEPVLAELIQSPLVSRLAYVHQGGSSYLVNPLWDLSRLDHSIGVMLFIRKFGGSLEEQIAGLLHDVSHTAFSHVVDYALDFEEEDYHEQIFEDFVKTSTIPAILEKYGYSFEGIFDDISKWKILEQEAPELCADRIDYTLQDLYRHGKISLAEVEEFLQALVMVDGRLYLANIALAEWFVAQYYSEVIDYFYDPLNVYSYEILAEAMRIAFQQETITTADLRLTDTELLAKLNANSDAREKIQLLASAHLEENEADFTYHHKKKMRLINPSILVDGRLIPADELSENVREMNDWASERSKHGIYIKATKKSKQ

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Crispr_ID: LT985475_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

LT985475_2

2105031-2105318

Orphan

Consensus_repeat	Method
ACATATTAGTAACGGAACTCGTATCAAAATTACTTACATCCAATTTCTCAAGTG	PILER-CR

3 spacers

The CRISPR arrays of LT985475_2

>merge|LT985475|2|2105031-2105318|PILER-CR
ACATAGTAGTAACGGAACTCGTATCAAAATTGCTTACATCCAATTTCTCAAGTGCTCTACAGGAACTAAACAAGGCTGACATATTAGTAACGGAACTCGTATCAAAATTACTTACATCTAATTCTTTAAGACTGGTACTATTAACAAACATGCCTCCCATATTAGTAACGGAACTCGTATCAAAATTACTTACATCCAATTTTTCAAGTGCTTTACAATCCCTAAACATATGATACATATCATTCACAGAACTCGTATCAAAATTACTTACATTCAATTTCTCAAGTG

>LT985475|2|1|2105031-2105318|PILER-CR
ACATAGTAGTAACGGAACTCGTATCAAAATTGCTTACATCCAATTTCTCAAGTG	CTCTACAGGAACTAAACAAGGCTG
ACATATTAGTAACGGAACTCGTATCAAAATTACTTACATCTAATTCTTTAAGAC	TGGTACTATTAACAAACATGCCTCCCATATTAG
TAACGGAACTCGTATCAAAATTACTTACATCCAATTTTTCAAGTGCTTTACAAT	CCCTAAACATATGATACATATCAT
TCACAGAACTCGTATCAAAATTACTTACATTCAATTTCTCAAGTG

Protein	Signature genes	Signature genes Name	Protein_function
LT985475.1\|SPE86015.1\|2112473_2112887_-\|YggS-family-pyridoxal-phosphate-enzyme	unknown	unknown	gnl\|CDD\|223402
LT985475.1\|SPE85991.1\|2097044_2097518_-\|hypothetical-protein	unknown	unknown	unknown
LT985475.1\|SPE85997.1\|2101683_2103834_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
LT985475.1\|SPE86007.1\|2110521_2111298_-\|RNA-binding-protein-S4	unknown	unknown	gnl\|CDD\|225185
LT985475.1\|SPE85981.1\|2093599_2094445_+\|nicotinate-nucleotide-pyrophosphorylase	unknown	unknown	gnl\|CDD\|181221
LT985475.1\|SPE85985.1\|2095865_2096132_-\|transposase	unknown	unknown	unknown
LT985475.1\|SPE85999.1\|2106385_2107924_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|368260
LT985475.1\|SPE86017.1\|2113005_2114181_-\|cell-division-protein-FtsZ	unknown	unknown	gnl\|CDD\|236468
LT985475.1\|SPE85989.1\|2096539_2097025_-\|hypothetical-protein	unknown	unknown	unknown
LT985475.1\|SPE86009.1\|2111422_2111713_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376765
LT985475.1\|SPE85995.1\|2099710_2101549_-\|membrane-protein	unknown	unknown	gnl\|CDD\|308794
LT985475.1\|SPE86003.1\|2108752_2109346_-\|TetR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
LT985475.1\|SPE86013.1\|2112197_2112419_-\|YggS-family-pyridoxal-phosphate-enzyme	unknown	unknown	gnl\|CDD\|223402
LT985475.1\|SPE85992.1\|2097583_2099575_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
LT985475.1\|SPE86001.1\|2107945_2108725_-\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|316372
LT985475.1\|SPE85987.1\|2096206_2096512_-\|cell-wall-surface-anchor-protein	unknown	unknown	gnl\|CDD\|273478
LT985475.1\|SPE85983.1\|2094441_2095542_+\|quinolinate-synthetase	unknown	unknown	gnl\|CDD\|236489
LT985475.1\|SPE85978.1\|2092148_2093603_+\|L-aspartate-oxidase	unknown	unknown	gnl\|CDD\|236147
LT985475.1\|SPE86005.1\|2109933_2110095_+\|hypothetical-protein	unknown	unknown	unknown
LT985475.1\|SPE86011.1\|2111735_2112194_-\|cell-division-protein-SepF	unknown	unknown	gnl\|CDD\|224712

Protein	Function_ID	Function_description	E-value
LT985475.1\|SPE86015.1\|2112473_2112887_-\|YggS-family-pyridoxal-phosphate-enzyme	gnl\|CDD\|223402	COG0325, COG0325, Predicted enzyme with a TIM-barrel fold [General function prediction only].	3.43073e-67
LT985475.1\|SPE85997.1\|2101683_2103834_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	2.47728e-32
LT985475.1\|SPE85981.1\|2093599_2094445_+\|nicotinate-nucleotide-pyrophosphorylase	gnl\|CDD\|181221	PRK08072, PRK08072, carboxylating nicotinate-nucleotide diphosphorylase.	0
LT985475.1\|SPE86007.1\|2110521_2111298_-\|RNA-binding-protein-S4	gnl\|CDD\|225185	COG2302, COG2302, Uncharacterized conserved protein, contains S4-like domain [Function unknown].	5.25746e-131
LT985475.1\|SPE85999.1\|2106385_2107924_-\|transcriptional-regulator	gnl\|CDD\|368260	pfam05043, Mga, Mga helix-turn-helix domain. M regulator protein trans-acting positive regulator (Mga) is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This domain is found in the centre of the Mga proteins. This family also contains a number of bacterial RofA transcriptional regulators that seem to be largely restricted to streptococci. These proteins have been shown to regulate the expression of important bacterial adhesins. This is presumably a DNA-binding domain.	4.97774e-19
LT985475.1\|SPE86017.1\|2113005_2114181_-\|cell-division-protein-FtsZ	gnl\|CDD\|236468	PRK09330, PRK09330, cell division protein FtsZ; Validated.	0
LT985475.1\|SPE86001.1\|2107945_2108725_-\|SAM-dependent-methyltransferase	gnl\|CDD\|316372	pfam13847, Methyltransf_31, Methyltransferase domain. This family appears to have methyltransferase activity.	2.04125e-12
LT985475.1\|SPE86009.1\|2111422_2111713_-\|hypothetical-protein	gnl\|CDD\|376765	pfam02325, YGGT, YGGT family. This family consists of a repeat found in conserved hypothetical integral membrane proteins. The function of this region and the proteins which possess it is unknown.	3.52749e-09
LT985475.1\|SPE85995.1\|2099710_2101549_-\|membrane-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	1.33873e-34
LT985475.1\|SPE86003.1\|2108752_2109346_-\|TetR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.0655e-06
LT985475.1\|SPE86013.1\|2112197_2112419_-\|YggS-family-pyridoxal-phosphate-enzyme	gnl\|CDD\|223402	COG0325, COG0325, Predicted enzyme with a TIM-barrel fold [General function prediction only].	1.42939e-25
LT985475.1\|SPE85992.1\|2097583_2099575_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	9.13135e-32
LT985475.1\|SPE86011.1\|2111735_2112194_-\|cell-division-protein-SepF	gnl\|CDD\|224712	COG1799, COG1799, Uncharacterized protein conserved in bacteria [Function unknown].	5.62658e-53
LT985475.1\|SPE85987.1\|2096206_2096512_-\|cell-wall-surface-anchor-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	0.000635685
LT985475.1\|SPE85983.1\|2094441_2095542_+\|quinolinate-synthetase	gnl\|CDD\|236489	PRK09375, PRK09375, quinolinate synthase NadA.	7.8764e-150
LT985475.1\|SPE85978.1\|2092148_2093603_+\|L-aspartate-oxidase	gnl\|CDD\|236147	PRK08071, PRK08071, L-aspartate oxidase; Provisional.	0

>LT985475.1|SPE85997.1|2101683_2103834_-|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFITFGSANVSTAQERDTANKLPEVELGSLDTSNIIAEEVTQEKPAEVEQLEEIPTTDELMQNPNVLEKSVADSDDPDLTVVSSGAYWTIYYNSANGEYSLRMFGNVPSSKPTAWNSYLSNIKHIEIEEATLTGSFEAYFRDNVFTVLESVRIEQCNLSGVTSFRSAFEGQLALEKVIIRDNYYPTTPTLRTTENMFLGCYNLREFDVSGLDTRAVTNMRAMFQNCTSLEELDVSNFDTSSVTTMQNMFQNCTSLEELDVSNFDTSSVTTMQNMFQNCTSLEELDVSNFDTRSVTSMAYMFYRSAGLKELDVSNFNTSSVTAIQGMFYDCSSLEELDVSNFDTRSVTSMTFMFLNCANLEELDVSNFNTRSVTSMTYMFGGCTSLKELDLSNFNTSSVTAMYNMFQNSTSLEELDLSNFNTSSVTNMSYMFQNCTALKSLYLDNFTTPKTMTDMFIGTTSLTYLFVSHNFKDFNGVENTNWFDEKNGVQFSNLSQLQTYHQQQREPTGYRKGVFLSLTMDAMGGQFEDAEEQKVQNKVSGEYWEEVVPVKEGHYFDGWYLDRNFTNKFDFSLPVAVSTTIYAKWVENYTVVIPASISLNEATELKVEGINRGSKTLSVGLNYEETTISESNKLTLANTADTTVQCLAPLSWDGSETNPEKVILTLAPGSEITEGDAVMAIEAPENIQAGTYTGNLVFSINYE
>LT985475.1|SPE85995.1|2099710_2101549_-|membrane-protein
MKKFSMRVVLIISVLFIAFGSANVSIAQEMDTTNKLPEEELGSLDTSNLIAEEVAQDKPAEVDNLEEIPTTDELMQNPEVLEQPVVDSDDPDLTVVSSGDFWTLYYNSANDEYSMRMFGNVPSSKPTAWNSYLKYIKHIEIEEATLTGSFASYFDNSAFPALESVRIEQCNLSGVTSFRTAFNNHLTLEKVIIKDNDYPTTSSLLTTEYMFSHAIKLTELDVSGLDTSAVTNMKNMFGGCNSLEELDLSNFDTSSVTNMSGMFGYCESLEKLNVSHLDTSSVTDMNAMFYGCTSLEALDVSNFDTSSVTDMRAMFADNEKLEKLDLSTFDTSSVTNMGTMFKDCTALKSLYLDNFTDAAIMTDMFKGTTSLTYLFVSHNLSTFTSLENTSWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGAFLSLTMDAMGGEFEDAEEQKVQSKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPATVSATLYAKWVENYTVVIPASISLNEATELKVEGINRGDKNLSVGLNRTATSVSESNKLTLANTADTTIQCLAPLSWDGSENNPKNAILTLAPGSEITEGEAVLAIEAPENIQAGTYTGNLVFSINYE
>LT985475.1|SPE85992.1|2097583_2099575_-|BspA-family-leucine-rich-repeat-surface-protein
MKKFSMRVVLIISVLFIAFGSANVSIAQEMDTTNKLPEEELGSLYTSNLITEEVAQDKPAEVEQLEEIPTTDELMQNPDVLEQPVADSDDPDLTVVSSGAYWTIYRNTVNGEYSLHMFGNVPSSRPTAWNSYLKSIKHIEIEEATLTGNFASYFDNSAFPALESVRIEQCNLSGVTSFASAFYSSGIEKVIIRDNDYPTAPSLLTTQSMFGYANKLTELDVSGLDTSAVTNMQNMFQYCRALEELDVSHFDTSSVTTMRGMFQYCELLDKLDVSNWDTSSVTTMMSAFAECNSLEILDVSNFDTSSVTDMTAMFQNCYALEKLNISNFDTSSVTKMYAMFSGLYEVGKLDASNFDTSLVTTMNRMFQNCKSLKELDIGNFNTSLVTDMDRMFINCAALKSLYLDNFTTAKTMTDMFTGTTSLTYLFVSHNLSTFTGLENTSWYDEKNWVQFSNLSQLQTYHRKQSEPTGYRKGEFLSLTMDAMGGEFEDAEEQKVQSKISGEYWEEVIPVKEGHYFDGWYLDQNFTNKFDFSLPAAVSTTIYAKWIENYTVIIPASISLNETSELKVEGINRGDKNLSVGLNRTATSISESNKLTLSNTADATVQCLVPLSWDGSENNPENAILTLAPGSEITEGDAVMEIKSPENIQAGKYTGNVVFSIKYD
>LT985475.1|SPE85991.1|2097044_2097518_-|hypothetical-protein
MKKKRVVIISLLLLLVSVIGISSYFLFKDKINLLDVDHSAVDWNGKKQKDTSGEENTIAIPGFEKVTLYANETTQAVNFHNPEINDCYFKISLIHPDGSVLWISDLIEPGKGMYSIELEKTLAVGEYENAVLKYECFSLNDQSPLNGSEINLKLVVV
>LT985475.1|SPE85989.1|2096539_2097025_-|hypothetical-protein
MNKLVLSTLSVAAMGMVFFSGGTAYAADKEGNTVVEYSVEGDYTLVVPEKVNLSNDNATEMSVKTINRNLEPGKEVEVTLSSGLSADGEIELQRVGAISDVITSSFKSNNSVVPMANPVIGSFSGYAMEETEVSKIQIGNPQGDKKAGAYQTTLTFTAAFK
>LT985475.1|SPE85987.1|2096206_2096512_-|cell-wall-surface-anchor-protein
MKRKLVLAMVLISFCGMFLLSPERVQASQTVVEVFISEDDLDVSEENIQEIPKKELAASSDKDNKQPILPKAGDTVTNYTLLGLVLVLIWLIMQRRSKKKE
>LT985475.1|SPE85985.1|2095865_2096132_-|transposase
MARIEYEEKIQKSLLVLYFRGSTIQSICREYGIPRYEFHKWMKLHDADKLETKEVKTFLQIRELKQQKNKLEEEILFLNEAINLLESP
>LT985475.1|SPE85983.1|2094441_2095542_+|quinolinate-synthetase
MNLLETVEQDTMPTHYKQMTQAEMIARVTEIKAQLGENLFIPCHHYQKDEVVPFADAIGDSLQLAQIAAQNKKAKHIVFCGVHFMAETADMLTTSEQIVTLPDMRAGCSMADMADIHQLTNAWPKLQTLFGDTILPVTYINSTAAIKSFVGEHGGTTVTSSNATKIVSWALEQKERIFFLPDQHLGRNTAFELGIPLEHMAIWNPIKNELEYEGNLDDCKVILWKGYCSVHQHFTVKNIENIRKNNPKMRIIVHPECTHEVVSLADDSGSTKKIVTEINNAAPGTEWAVGTEANLVGRIIQENPDKKIVSLNPFMCPCMTMNRIDLPHLLWTLEAIQNGEQRNQIKVDKQTTKFALKALERMLQLS
>LT985475.1|SPE85981.1|2093599_2094445_+|nicotinate-nucleotide-pyrophosphorylase
MNSILMNQAIQAFLLEDIGQHDLSAETVFPRDTMGEGVFLAKETGILCGISIPPKVYELLGGNIQFEAYKKDGDWIQKGDIIAAVTAPVRTLLSGERVILNLMQRMSGIASQTNFAVKQLDDSAIRICDTRKTAPGLRAFDKYAVQTGGGFNHRNGLYDGVMLKDNHIAFSGGITSAVSTVREKLGHMVKIEVETETAEQVKEAVQAGADIIMFDNRTPEEIKQLVKLVPPHITTEISGNVTLENIHRYKGSGANYLSLGSLTHSVRAFDISFNSKGGIKA
>LT985475.1|SPE85978.1|2092148_2093603_+|L-aspartate-oxidase
MTKERVIIIGSGIAGCTAAFRLMHDYDVTIITKGLKEESNSMLAQGGVAAAVSKNDTPKKHFSDTFQAGCFHNKVLAVNQLVTNGPIVIQKLIAEGMTFDEQNGELSLGLEGAHQLPRILHTGGDQTGKFLTTFLQEKLTNIHWQEQKMAIEIIKQNDSAIGVHCLDKENRLHTYYGEHIILASGGLGQLFPVTTNAATISGDGLALAYRAGAKLTDMEFIQFHPTLLFLNGRCHGLISEAVRGEGAKLIRADGSAVMTDVHPRADLAPRDIVAATLFAEIQDGNEVFLDITPIPNFEERFPGITANLDAYHVPFRETKRIPVHPGAHFLMGGIRTDLQGKTNIPGLYAIGEVANAGVHGANRLASNSLLETLVFGEKVAEYILTQKTNLIDHPEIPLSNQTQTPHLPDKQLLQEKIWETLGITRKPEKITEFLHWLTDFDYANHTRETAEISHMLITAKLIAESALKRTESLGAHRILKGVIK
>LT985475.1|SPE85999.1|2106385_2107924_-|transcriptional-regulator
MREYLDSKSQKKVALLEKIFYAENHTSTQEELLNDLNITYPTLISTIKTINFDIERFGYKAFSIVHSAPNLSYTLKISDNCSIQLIINAYIRESPKFQILETLLLASFPNLQVLANEVHVSYSGIKKEIKELNEELRERNLSISTGSQVEITGDEFSLRIFYTFLFLVAYSGDRWPFSFVQYDEITDILESCPKEIYRANSIDKAMMIHYYVAMHLLRDRMNCQIDTTRQFKVALYKACTEESKKSESAFIKKVAKQLPNRNYKEMTYTTQIILSTIVAFGSYSSIEKMPSFFYMDEQLEEMGFMKLVDFASEQVNDNLSIPFSEKEMELLRYSFASINYRYFLLDNLINKFNNIVPGYTDLDRNIRKIHKVNHLEPLISQLVNLKEMDSLKPFEERLASDYLIILDKRIDFSIHTLPIKVTILSTISNETAVFDFMRYFSSYYNLEILNQVDSVVDLYISDFSVSPEVLTSLRINQPIIYVNTRWLESDYVKINDNLAKIARKKFIANKKD
>LT985475.1|SPE86001.1|2107945_2108725_-|SAM-dependent-methyltransferase
MNKETERKLAASLTSQSIEILPFIPYFLQDFFELGSSPKDITYLIKQHMPLSAESNFLDLACGKGAVSIGIAKELGNPVKGIDLIPAFIEEAKCKAKEAQVESLCQFEVGDVNKSVQNEKNYDAVIFGAAADILGNPAETLEKLQGTVKEGGYIIIDEAYVPELAHNNQVKYQNYEYLTRKEWLNLFEQNQLQLVEELEGTAEVDFELEKQHLLTRANELIQQYPEKKALFEGYLKSQWSEYDDLEEYLIAVTWILHKK
>LT985475.1|SPE86003.1|2108752_2109346_-|TetR-family-transcriptional-regulator
MPKLVTGYERQQTKNLIIEHTSHLIYIKKGIQGFTVEDITRAARIGKRKFYTCFPSKEACLFEVVEYSYQAQLEAFKKIMEEKGSLKSKMTRFLKEVYLSEKSINNYFSPEDFHAILQKLPPTYTEREERMTSEVLETAMTYIDLTRAQWEALVMLLDCLTYTATRSYVETAKKAKEETLDILIHSIADYVEKQTQC
>LT985475.1|SPE86005.1|2109933_2110095_+|hypothetical-protein
MKIILEFLFRELLSLAIEYGVNWLILNDHIYILIIIVSFIVRCFVETRDKKYF
>LT985475.1|SPE86007.1|2110521_2111298_-|RNA-binding-protein-S4
MDGIYQHFRAEEYAFIDKILGITMQVENEYTPQLTDFLDPRQRFITETVIGGYDEINVQFFGGVAHAERRRALIYPDYYTPTEADFEIALFHIRYPVKFTTLTHQKILGTLMSLGMKRDIFGDILNNGSEWQLLVESTMKDYLTLQLEKIGKVNVMLEETDLANAVYAPVVWEEMGLTVSSMRLDVIISNVHHISRQKAKQLVTAGLVKVNWKTVENPDFECEEEDVLSARGYGRVKVLSTGGRTKKDKIRIEIGYLK
>LT985475.1|SPE86009.1|2111422_2111713_-|hypothetical-protein
MQSILYQVVEIILFIIRWLPTLMFIYFLMSWFPGARESKIGQFLARIFEPILEPFRRIIPPIGMFDISSLVAYFIFQYAMRVLTGLIQVYVIPMLF
>LT985475.1|SPE86011.1|2111735_2112194_-|cell-division-protein-SepF
MGLSNKFKSFFFLDEEEEYYEEEVAREPEPMQKKTKKEKPNKNRFYAVEEDDAKVVSMQGAQFSSRMVLAEPRVYAEAQELADYLKEYKSVVVNLQRISHDQATRIVDFLSGTVYALGGDIQRVGNNIFLCTPDNVEVDGSISEMLDEQNFM
>LT985475.1|SPE86013.1|2112197_2112419_-|YggS-family-pyridoxal-phosphate-enzyme
MTMAPITNSDIELHHVFHELKQLQQEIHALQLNNIPCTELSMGMTNDYGVAITEGATFIRVGRALVSDDNMEV
>LT985475.1|SPE86015.1|2112473_2112887_-|YggS-family-pyridoxal-phosphate-enzyme
MTKQANLQKVTAQIERACEESNRQPEDVTLVAVTKTIDVAGITELYDLGIRHFGENRADVFQEKTVALADKEDICWHYIGSLQTRKVKDVLPKIDYLHSLDRSSLAKEIEKRATKQVKCFLQVNISGEESKHGFSKE
>LT985475.1|SPE86017.1|2113005_2114181_-|cell-division-protein-FtsZ
MLEFDTSSESLATIKVIGVGGGGNNAVNRMIEHGVQGVEFISVNTDAQALNLAKAETKLQIGTKLTRGLGAGAVPEIGKKAAEESREQIEEALKGSDMVFVTAGMGGGTGTGAAPVIAQIAKEMGALTVGVVTRPFGFEGPKRTKQALTGTEAMKEAVDTLIVIPNDRLLQIVDKNTPMLEAFREADNVLRQGVQGISDLIAVPGLINLDFADVKTIMTNRGSALMGIGIATGENRAAEAAKKAISSPLLETSVDGAKGVLMNITGGSNLSLYEVQEAAEIVSSASDEDVNMIFGSVINDELKDELIVTVIATGFDEEKQAQQQAQANRRPNQSIQVNRPNYAVQDEQQNDYAQNAPQQANAPVHEQQAEPQQNSSDVDVPAFIRNRNRRG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

123377 : 129904

Listeria_phage(33.33%)

tail

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SPE82740.1\|123377_123839_-	toxin	A0A059T7S0	Listeria_phage	3.1e-31	47.9
SPE82741.1\|123835_124171_-	repressor C1	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
SPE82743.1\|124387_124816_+	hypothetical protein	NA	NA	NA	NA
SPE82744.1\|124827_125244_+	transcriptional regulator	A8ASQ1	Listeria_phage	1.3e-20	38.6
SPE82746.1\|125523_125913_+	antigen B	NA	NA	NA	NA
SPE82748.1\|125925_126438_+	antigen A	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
SPE82750.1\|126485_126788_+	hypothetical protein	NA	NA	NA	NA
SPE82752.1\|126829_127234_+	hypothetical protein	NA	NA	NA	NA
SPE82754.1\|127220_129089_+\|tail	phage tail protein	A0A097PAU2	Streptococcus_pyogenes_phage	3.5e-20	45.8
SPE82755.1\|129085_129904_+\|tail	phage tail family protein	A0A2H4JAE4	uncultured_Caudovirales_phage	1.7e-40	34.9

DBSCAN-SWA_2

1272460 : 1329312

Bacillus_virus(16.67%)

protease,tRNA,integrase

attL 1281426:1281442|attR 1316613:1316629

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SPE84479.1\|1272460_1273600_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
SPE84481.1\|1273679_1274075_-	transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
SPE84483.1\|1274225_1274441_+	transcriptional regulator	NA	NA	NA	NA
SPE84485.1\|1274564_1275098_+	hypothetical protein	NA	NA	NA	NA
SPE84487.1\|1275113_1275779_+	hypothetical protein	NA	NA	NA	NA
SPE84488.1\|1276040_1276979_+	hypothetical protein	NA	NA	NA	NA
SPE84490.1\|1277093_1278377_+	trigger factor	NA	NA	NA	NA
SPE84492.1\|1278561_1279821_+\|protease	ATP-dependent protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
SPE84494.1\|1279939_1280506_+	type I signal peptidase	NA	NA	NA	NA
SPE84496.1\|1280540_1281110_+	type I signal peptidase	NA	NA	NA	NA
SPE84498.1\|1281211_1281754_+	type I signal peptidase	NA	NA	NA	NA
1281426:1281442	attL	NA	NA	NA	NA
SPE84500.1\|1281763_1282627_+	ribosomal biogenesis GTPase	NA	NA	NA	NA
SPE84501.1\|1282623_1283409_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	6.7e-26	37.6
SPE84503.1\|1283542_1284403_+	DNA processing protein DprA	NA	NA	NA	NA
SPE84506.1\|1284675_1286754_+	DNA topoisomerase I	A0A1V0SB35	Catovirus	5.4e-107	37.5
SPE84508.1\|1286816_1288121_+\|tRNA	tRNA (uracil-5-)-methyltransferase Gid	NA	NA	NA	NA
SPE84510.1\|1288403_1289306_+\|integrase	integrase/recombinase	A0A142K7N4	Mycobacterium_phage	1.8e-14	29.5
SPE84512.1\|1289326_1289866_+\|protease	ATP-dependent protease peptidase subunit	NA	NA	NA	NA
SPE84514.1\|1289879_1291289_+\|protease	ATP-dependent protease ATP-binding subunit HslU	W6AS21	Erwinia_phage	7.5e-44	27.8
SPE84516.1\|1291309_1292089_+	transcriptional repressor CodY	NA	NA	NA	NA
SPE84518.1\|1292191_1292611_+	Putative esterase	NA	NA	NA	NA
SPE84520.1\|1292633_1292945_+	hypothetical protein	NA	NA	NA	NA
SPE84522.1\|1292947_1293820_+	LacX protein	NA	NA	NA	NA
SPE84524.1\|1293861_1294458_-	glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
SPE84526.1\|1294615_1295023_+	CoA-binding protein	NA	NA	NA	NA
SPE84527.1\|1295203_1297171_+	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	8.7e-123	42.5
SPE84530.1\|1297167_1299627_+	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.1e-101	31.8
SPE84532.1\|1299709_1300177_+	S-ribosylhomocysteinase	NA	NA	NA	NA
SPE84534.1\|1300804_1302625_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
SPE84536.1\|1302657_1304544_-	acetyltransferase	B5WZU0	Pseudomonas_phage	3.8e-43	32.2
SPE84538.1\|1304756_1305455_+	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	6.4e-12	31.9
SPE84540.1\|1305687_1307364_+	glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
SPE84542.1\|1307490_1308408_+\|tRNA	tRNA delta(2)-isopentenylpyrophosphate transferase	NA	NA	NA	NA
SPE84544.1\|1308529_1308763_+	host factor-1 protein	NA	NA	NA	NA
SPE84545.1\|1308873_1310097_+	GTPase HflX	NA	NA	NA	NA
SPE84546.1\|1310089_1311316_+	aluminum resistance protein	NA	NA	NA	NA
SPE84548.1\|1311517_1311886_+	glutamine synthetase repressor	NA	NA	NA	NA
SPE84550.1\|1311956_1313291_+	glutamine synthetase	A0A1V0SJ53	Klosneuvirus	2.0e-06	26.4
SPE84552.1\|1313434_1314730_+	arsenic transporter	A0A2H4PQU3	Staphylococcus_phage	2.5e-147	62.6
SPE84554.1\|1314763_1315288_-	N-acetyltransferase	NA	NA	NA	NA
SPE84556.1\|1315318_1315933_-	LexA family transcriptional regulator	A0A1B2APZ1	Phage_Wrath	9.3e-15	62.1
SPE84558.1\|1316089_1316419_+	cell division suppressor	NA	NA	NA	NA
SPE84560.1\|1316512_1316740_+	hypothetical protein	NA	NA	NA	NA
1316613:1316629	attR	NA	NA	NA	NA
SPE84561.1\|1316886_1318881_+	transketolase	NA	NA	NA	NA
SPE84563.1\|1319101_1319341_+	hypothetical protein	NA	NA	NA	NA
SPE84565.1\|1319389_1320121_-	class I SAM-dependent methyltransferase	A0A1X9I6N4	Streptococcus_phage	2.3e-81	58.0
SPE84567.1\|1320142_1320649_-	chromosome partitioning protein ParB	A0A220GKT8	Streptococcus_phage	1.4e-56	66.7
SPE84569.1\|1320658_1321963_-	phosphoadenosine phosphosulfate sulfurtransferase	A0A220GKF8	Streptococcus_phage	1.2e-133	52.1
SPE84571.1\|1321952_1323152_-	helicase SNF2	L0P6E9	Lactobacillus_phage	5.3e-91	46.6
SPE84573.1\|1323135_1323510_-	hypothetical protein	NA	NA	NA	NA
SPE84575.1\|1323802_1324531_+	uridylate kinase	NA	NA	NA	NA
SPE84577.1\|1324530_1325088_+	ribosome recycling factor	NA	NA	NA	NA
SPE84579.1\|1325318_1326077_+	UDP pyrophosphate synthase	R9W0U9	Flavobacterium_phage	4.4e-22	42.1
SPE84581.1\|1326090_1326879_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
SPE84583.1\|1326893_1328036_+	1-deoxy-D-xylulose 5-phosphate reductoisomerase	NA	NA	NA	NA
SPE84585.1\|1328049_1329312_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA

DBSCAN-SWA_3

1825019 : 1833305

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SPE85479.1\|1825019_1825586_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	2.8e-26	38.5
SPE85481.1\|1825582_1826632_-	phosphoribosylaminoimidazole synthetase	Q58MH8	Prochlorococcus_phage	3.2e-63	44.4
SPE85483.1\|1826650_1828078_-	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.4e-53	31.9
SPE85485.1\|1828062_1830282_-	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	6.5e-159	40.8
SPE85487.1\|1830274_1830958_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
SPE85489.1\|1830961_1831207_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
SPE85490.1\|1831218_1831932_-	phosphoribosylaminoimidazole-succinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	2.0e-40	38.3
SPE85492.1\|1832012_1833305_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.5e-17	33.0

DBSCAN-SWA_4

2520298 : 2528143

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
SPE86602.1\|2520298_2521270_-	sporulation regulator WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
SPE86604.1\|2521277_2522246_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.8e-68	43.6
SPE86606.1\|2522247_2523123_-	RNase adaptor protein RapZ	A0A0R8VB27	Thermobifida_phage	1.9e-08	29.7
SPE86608.1\|2523230_2524961_-	phosphoglucomutase	A0A1X9I671	Streptococcus_phage	9.5e-174	53.1
SPE86610.1\|2525002_2525995_-	aldose 1-epimerase	NA	NA	NA	NA
SPE86612.1\|2526080_2527064_-	UDP-glucose 4-epimerase	A0A2K9L5H6	Tupanvirus	4.0e-52	38.1
SPE86614.1\|2527183_2528143_-	thioredoxin reductase	G3MA85	Bacillus_virus	2.0e-88	53.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. LT985475

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection