CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP032698	Streptomyces hundungensis strain BH38 chromosome, complete genome	95 crisprs	csa3,WYL,DEDDh,DinG,cas4,cas3	81	60	3	1

1. CP032698

CRISPR-Cas detection and classification

Crispr_ID: CP032698_1

• CRISPR_ID: CP032698_1
• CRISPR_location: 274683-274756
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_1

Consensus_repeat	Method
CCGGTCACCGCGCCGGGCCGCTCA	CRISPRCasFinder

spacers of CP032698_1

>1.1|274707|26|CP032698|CRISPRCasFinder
TGCGGGGCGGTCGCCGGACAGACGAC

CRISPR arrays and Neighbor proteins around CP032698_1

CRISPR arrays

The CRISPR arrays of CP032698_1

>merge|CP032698|1|274683-274756|CRISPRCasFinder
CCGGTCACCGCGCCGGGCCGCTCATGCGGGGCGGTCGCCGGACAGACGACGCCGGTCCCGCGCCGGGCCGCTCA

>CP032698|1|1|274683-274756|CRISPRCasFinder
CCGGTCACCGCGCCGGGCCGCTCA	TGCGGGGCGGTCGCCGGACAGACGAC
GCCGGTCCCGCGCCGGGCCGCTCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG78184.1|282231_282822_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG78177.1|274847_275729_+|NAD-dependent-protein-deacetylase	unknown	unknown	gnl|CDD|238700
CP032698.1|AYG78171.1|266508_267453_+|hypothetical-protein	unknown	unknown	gnl|CDD|309685
CP032698.1|AYG78178.1|275964_277074_+|hypothetical-protein	unknown	unknown	gnl|CDD|225926
CP032698.1|AYG78185.1|282858_283743_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG78181.1|278627_280118_-|Carboxylesterase	unknown	unknown	gnl|CDD|225181
CP032698.1|AYG78176.1|273392_274607_+|Nisin-biosynthesis-protein-NisB	unknown	unknown	gnl|CDD|274836
CP032698.1|AYG78179.1|277445_277805_+|hypothetical-protein	unknown	unknown	gnl|CDD|237030
CP032698.1|AYG78173.1|269269_270853_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG78175.1|271959_273351_-|hypothetical-protein	unknown	unknown	gnl|CDD|274846
CP032698.1|AYG78167.1|263272_263971_+|hypothetical-protein	unknown	unknown	gnl|CDD|132716
CP032698.1|AYG78183.1|281232_282063_+|2-(acetamidomethylene)succinate-hydrolase	unknown	unknown	gnl|CDD|223669
CP032698.1|AYG78174.1|271027_271969_-|Putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|197715
CP032698.1|AYG78169.1|265165_265633_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG78182.1|280215_280815_+|HTH-type-transcriptional-regulator-BetI	unknown	unknown	gnl|CDD|132427
CP032698.1|AYG78170.1|265723_266080_+|HTH-type-transcriptional-regulator-ZntR	unknown	unknown	gnl|CDD|133398
CP032698.1|AYG78172.1|267759_268563_-|hypothetical-protein	unknown	unknown	gnl|CDD|379483
CP032698.1|AYG78168.1|264556_264988_+|hypothetical-protein	unknown	unknown	gnl|CDD|380093
CP032698.1|AYG78180.1|278048_278210_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG78186.1|284242_286066_-|hypothetical-protein	unknown	unknown	gnl|CDD|237057

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG78177.1|274847_275729_+|NAD-dependent-protein-deacetylase	gnl|CDD|238700	cd01409, SIRT4, SIRT4: Eukaryotic and prokaryotic group (class2) which includes human sirtuin SIRT4 and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span.	1.94517e-137
CP032698.1|AYG78171.1|266508_267453_+|hypothetical-protein	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	2.05421e-47
CP032698.1|AYG78178.1|275964_277074_+|hypothetical-protein	gnl|CDD|225926	COG3391, COG3391, Uncharacterized conserved protein [Function unknown].	6.81679e-11
CP032698.1|AYG78181.1|278627_280118_-|Carboxylesterase	gnl|CDD|225181	COG2272, PnbA, Carboxylesterase type B [Lipid metabolism].	4.89246e-91
CP032698.1|AYG78176.1|273392_274607_+|Nisin-biosynthesis-protein-NisB	gnl|CDD|274836	TIGR03891, lantibiotic_dehydratase, thiopeptide-type bacteriocin biosynthesis domain. This domain occurs within longer proteins that contain lantibiotic dehydratase domains (see pfam04737 and pfam04738), and as single-domain proteins in bacteriocin biosynthesis genomic contexts. Three named genes in this family, SioK in Streptomyces sioyaensis, TsrD in Streptomyces laurentii, and NosD in Streptomyces actuosus, all occur in regions associated with thiopeptide biosynthesis. [Cellular processes, Toxin production and resistance].	3.33865e-50
CP032698.1|AYG78179.1|277445_277805_+|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.000211126
CP032698.1|AYG78175.1|271959_273351_-|hypothetical-protein	gnl|CDD|274846	TIGR03903, TOMM_kin_cyc, TOMM system kinase/cyclase fusion protein. This model represents proteins of 1350 in length, in multiple species of Burkholderia, in Acidovorax avenae subsp. citrulli AAC00-1 and Delftia acidovorans SPH-1, and in multiple copies in Sorangium cellulosum, in genomic neighborhoods that include a cyclodehydratase/docking scaffold fusion protein (TIGR03882) and a member of the thiazole/oxazole modified metabolite (TOMM) precursor family TIGR03795. It has a kinase domain in the N-terminal 300 amino acids, followed by a cyclase homology domain, followed by regions without named domain definitions. It is a probable bacteriocin-like metabolite biosynthesis protein. [Cellular processes, Toxin production and resistance].	0.000265456
CP032698.1|AYG78167.1|263272_263971_+|hypothetical-protein	gnl|CDD|132716	cd07040, HP, Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction. Catalytic domain of a functionally diverse set of proteins, most of which are phosphatases. The conserved catalytic core of this domain contains a His residue which is phosphorylated in the reaction. This set of proteins includes cofactor-dependent and cofactor-independent phosphoglycerate mutases (dPGM, and BPGM respectively), fructose-2,6-bisphosphatase (F26BP)ase, Sts-1, SixA, histidine acid phosphatases, phytases, and related proteins. Functions include roles in metabolism, signaling, or regulation, for example F26BPase affects glycolysis and gluconeogenesis through controlling the concentration of F26BP; BPGM controls the concentration of 2,3-BPG (the main allosteric effector of hemoglobin in human blood cells); human Sts-1 is a T-cell regulator; Escherichia coli Six A participates in the ArcB-dependent His-to-Asp phosphorelay signaling system; phytases scavenge phosphate from extracellular sources. Deficiency and mutation in many of the human members result in disease, for example erythrocyte BPGM deficiency is a disease associated with a decrease in the concentration of 2,3-BPG. Clinical applications include the use of prostatic acid phosphatase (PAP) as a serum marker for prostate cancer. Agricultural applications include the addition of phytases to animal feed.	0.00131077
CP032698.1|AYG78183.1|281232_282063_+|2-(acetamidomethylene)succinate-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.36815e-15
CP032698.1|AYG78174.1|271027_271969_-|Putative-HTH-type-transcriptional-regulator	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	5.79932e-17
CP032698.1|AYG78186.1|284242_286066_-|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	1.42443e-06
CP032698.1|AYG78182.1|280215_280815_+|HTH-type-transcriptional-regulator-BetI	gnl|CDD|132427	TIGR03384, betaine_BetI, transcriptional repressor BetI. BetI is a DNA-binding transcriptional repressor of the bet (betaine) regulon. In sequence, it is related to TetR (pfam00440). Choline, through BetI, induces the expression of the betaine biosynthesis genes betA and betB by derepression. The choline porter gene betT is also part of this regulon in Escherichia coli. Note that a different transcriptional regulator, ArcA, controls the expression of bet regulon genes in response to oxygen, as BetA is an oxygen-dependent enzyme. [Regulatory functions, DNA interactions].	1.14599e-06
CP032698.1|AYG78170.1|265723_266080_+|HTH-type-transcriptional-regulator-ZntR	gnl|CDD|133398	cd04770, HTH_HMRTR, Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators. Helix-turn-helix (HTH) heavy metal resistance transcription regulators (HMRTR): MerR1 (mercury), CueR (copper), CadR (cadmium), PbrR (lead), ZntR (zinc), and other related proteins. These transcription regulators mediate responses to heavy metal stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.01538e-31
CP032698.1|AYG78172.1|267759_268563_-|hypothetical-protein	gnl|CDD|379483	pfam14124, DUF4291, Domain of unknown function (DUF4291). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 190 and 214 amino acids in length. There are two conserved sequence motifs: VYQAY and RMTW.	6.7821e-112
CP032698.1|AYG78168.1|264556_264988_+|hypothetical-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	5.2247e-27

Protein sequences

>CP032698.1|AYG78176.1|273392_274607_+|Nisin-biosynthesis-protein-NisB
MAEPRSWATEFASWAERSGLPRRVLLGTGDQRVEIDASRPAHVELIRREAARGLPLTLEEAPFLPGPQGPEPGDGWLTGPAGAYTSEVIFPLLTRPPVATSRPGRPQPAEPPHLVGGPWLYAKLYVAYERHDEVIAAHLPDLLARLGGSVDRWFFLRYGDPDPHLRLRFHGRAEPPAREAPPRLHAWAARLRAAGLLRRMVVDEYRPETARYGGPQALELAERVFQADSELVSAQLSALRDGSLHGDPVVLGAVNQLDALRAMAGPEPWAPWLLARYPRVPHTASSRKRQRILDQLLDETTDLLAPGAPGPAPAPAPTLVRLVGPGRLAAASTVRAEVLVEYGRVLRGLGRGLSAEEGRATPLPSVLHLHYNRAVCIPPAAEDTVLALVRNAVQARLDRRAQQP
>CP032698.1|AYG78175.1|271959_273351_-|hypothetical-protein
MDDGQWLDTASAAALAFASRRLESVRVSMVLSVPDGEDVPACVAGARELRLGRLPTATARCLLDEYAPGATPSVRKRLLAEAQGNPMALAELPSALSDDQLTGIQALPDQLPLSEGVRQIFCGRVAAYGFPLLLAAAERDGDLPTLLSAAGDEDGAMDQLTGAARAGLITLHGQQVRFRHPLTRSATYQNAAPSRRRAAHRALADALDPGDDRRVWHLAAYATRPDDSLARLLANLADRTRHTGSVTTAVRALRRAATLSSTPAGTARWLVEAAECAWAAAEPTQARALLKDAESLVHAPELRARVARVRGAMLHAGSALNPACDTLMDSARLARSKAPQLAAESLLLAARAAWGANEPAKLTEIADLLADLALKETPERSQLVYQLRRMAGAPVPTNGPEQPGAKSCPSGDERPTSSCLGPLVWPPLFVPYLLGDGEAGLEGQRRTFESLRAAGAVGAMRWG
>CP032698.1|AYG78174.1|271027_271969_-|Putative-HTH-type-transcriptional-regulator
MGLTSFVAAQLVTGRWADAVALGQQGLTLATDTGQLTARCHLQALLAYVAAAQGDSARCRELAEAALAESVPRRAASAAALARWAQGVDALGGRRPRQAVGPLSEVITRGGTAEHFMLSGLVLPDLVEALVRVGQTERAAAPLGQFEEQADPLNAPSLRAAWHRCRALLATAHDADRHFADALAAPCTSGFETGRAHLLYGQWLRRHRHVTAARRHLHQAVEHFLTVGAEPWTEQANMELRAAGVPDTEPPANGRGLTPRELQIARYAAQGLTNKDIGSRLFLSPRTVGYHLYKIYPKLNITSRRQIAHLVLA
>CP032698.1|AYG78173.1|269269_270853_+|hypothetical-protein
MSTPVHRTPAPQAAAALTSARQRGEGSLSGNSLEHAFLRMQSSAGNRAATAAVQRARGMDKGKEKGKGEVPKAGGVSAGAKKSYRDEIAGLLDRFKKSLDPIDTFIKGVQTPTNAGFTQQAAAAANEGLKHSVAASGTSAASENLLTEATGTLVNGMDAYKNMKDAKKHRTGAGHHTAQKKAKTKGADTVIGAAGSASYSAGIAKEVTKLHKAADAAVASEASGIASASVGAIKGIRAAFRVGGAASKYRKVKELGDPHLVHAQSLARLNQSREQAEWAAAEAYVALDAYWDHEGEERLELVSEAIDAAWEATGEARAAAESLQRAEKDVEKLNSVQEYAKKKQLTKIGKETIGGALGESTKAAAGVVTAVAAGTAGLASNPVGWGLAGAGAGLVLGVTLYKALRAATKRYEEARHPEHWAPENETPAEASSRSESLKHALKFWQKVSKGERQAMAREIYALAAGPDITGAGSTTAEMRDSARALLNALKSGPAHHKLDPETWADTLNDPAKTTGWIKEIAEQLASG
>CP032698.1|AYG78172.1|267759_268563_-|hypothetical-protein
MTHLAVRPIPRRSRNEPRHSSRNSCPRSTEPLSLLDDPRYEQRSSGQAQPATSGLIIRWRDAQPTSTLVTVSEPKHQIRALYTASTVTVYQAYAAEIGRPAAEVGRFPAAWKRDRMTWIKPSFLWMMYRCGWATKEGQEIVLAIEITREGFEWALKNACLSHYERGLHPDCAAWKRQLKRAPARVQWDPERDLHLQPLPHRSLQLGLAGEAAERYAEEWIVSINDVTALAHATHAHVRDGALDAARQLLPAERPYPSADTLLTHLSR
>CP032698.1|AYG78171.1|266508_267453_+|hypothetical-protein
MAFSRSQPQVEVPAALATSQKSDAWQAWTAALPSLAEEFLDRWSLRLDGPAAHGSVALVLPVLQADRSPAVLKLQTVDEETQGEPLALRAWGARHAVGLLNTAPDSGAMLLERLDAARSLATVPDGTAALRHLSELLKRLAAVRAPTGLRLLADIARDILDRVPTYSRSLTDPSERRLLATCADAMRELLDEPGDRLLHWDLHYDNVLAPLPSLQFPGRAPWLAIDPKPLAGDPGFELLPALRNRWDDMTGTADVPRAIRHRFHLMTEVVGLDRDRATGWTLGRVLQNCLWDIEDGAVTLEPEQKAIAHALLGS
>CP032698.1|AYG78170.1|265723_266080_+|HTH-type-transcriptional-regulator-ZntR
MRIGELAAQAGLTRDTIRFYEKIGLVTGRRLANGYRDFPPEAVPWLQYVRTAQTLGFSLAEIAQTGQELRNAPDTAEALSALFEEKIKVIDARMAQLVALRAELDARVGTGCPLRAAG
>CP032698.1|AYG78169.1|265165_265633_-|hypothetical-protein
MFRLFAPSHPAYLRAVRTSAWYDLVVTAGFATPWTYALVHDALSKFGDALGLGALPVLDPIEILYANLMGSVVVVWALLRIINPLPVHGLFDGTARTLFSAWQGYALAHGAPRWLWLFFVAEVAFGVVQLVPWWRARRTDLMGLSAVQPHGDAGR
>CP032698.1|AYG78168.1|264556_264988_+|hypothetical-protein
MSTIKQFQVTFDCADPVRLAAFWCEVLGYVMPEVPEGFATWEECFRSLPPEDAIYFACTDPTDVAPRLLFQRVPEGKVAKNRVHLDVRAGVGLVGDERLATLEAECARLMALGAKHVLTQRADGVNESCITMQDIEGNEFCLA
>CP032698.1|AYG78167.1|263272_263971_+|hypothetical-protein
MDRYAEQPCSLSRRGAIAGLGVISLLLAGCGSKGGGSASKSPSAQAASSSRRATTGGGGSTVDLVVMIIRHAEKPVGNETGKDDTGRRDRHSLTERGWARANALPRLFDPRPAPGLVRPIKVYAASDRGQDAGGHRMRQTVTPLAKRLGLAVDLDYAESKEADLAAAVSASPGPVLICWEHSRIPAIVEALAPQSGAPATWPERFDLIWVLTRTAGTWSFNTVDEHLLDADA
>CP032698.1|AYG78177.1|274847_275729_+|NAD-dependent-protein-deacetylase
MRPTLSWTPTGEVPPGTTDVGPVTDALSSGGVLVLSGAGLSTESGIPDYRGEGGSLSRHTPMTYQDFTASAQARRRYWARSHLGWRTFGGARPNSGHRAVAAFDRHGLLAGVITQNVDGLHQAAGSEDVVELHGSLERVVCLSCGAISPRRTLARRLEEANAGFEPTAAAINPDGDADLTDEQVRDFRVLSCTVCDGILKPDVVFFGESVPPQRVERCRAMVREASALLVLGSSLTVMSGLRFVRQAAQADRPVLIVNRDPTRGDQYAVTRVALPLGATLTAVADRLGVTVDK
>CP032698.1|AYG78178.1|275964_277074_+|hypothetical-protein
MKSLADRARWALMLLCVGLLVGTGAGVAEGRPHPGTEGVTRLPSSQYAVAPLISTDGTRAYVPSIDDVGTSLDVVNTRTGNVTAHVPTSSDRWAGPLLFNAGGKQIYLLTIGALKVFDTATNTLRSSFPIPDQPRPAGSNPGSLTRMAISPDGASIYMNQTGPDNGAQSTGPSRMLVFSTARRAFTATVPLPGESPRAVVVRPNGKDVYVSGDAGLIHLDASTGVPTLVRTLSATGFVDELALTPDGRRVYALSKPDGHAVLVDLDSDQVLTTIDFQSNYQPVLSPAVSPDGSRFYVLEDDQRSEAKVLSYKTATNTRVTRETVTGLAMEHGTGLTLGPDVETIDGETMYVTGVNYAENPGAFLQIVHF
>CP032698.1|AYG78179.1|277445_277805_+|hypothetical-protein
MRATWTAAALTAALALTPVASAAATPRLGADTPQPITAPAPPTVPPVAAIPTGPVADPVAQAKTETPTAPQITPSAPAADGGTGGLLSVVTNLVSTLQNVLSSLTGGLSSAKPPAPPHA
>CP032698.1|AYG78180.1|278048_278210_+|hypothetical-protein
MVPLLLVLLLALILFGAGFALKALWWVAVIVLVVWLIGFVARPKGGSGRWYRW
>CP032698.1|AYG78181.1|278627_280118_-|Carboxylesterase
MSEQPKVRTAEGVVQGRRRKGHAVFRGIPYAQPPVGALRFAAPAPPHRWEGTRQAVEFGPMVPLSLPIDVPRQGTDWLTLNVGTPDPGAAGLPVLVWIPVGGYLSAASSDPMLDPAALAAAGVVVVTINCRVGAEGFAFLDDVPPNRGFLDQIAALEWVQRNIASFGGDPCQVTVAGVSAGAGSVAALLTMKSARGLFRRAIAHSVPGLHSTPALARQVTAAFADRLGAAAPTAEALRDIDPWHLAAELTSFNAGLHAYRESWGRLAQTGTALCPVIDGEVLPETPWPALTGRRASGTELLVGHTRDEFRYFSVMSGRYGTFTEEDAHAALELHAPQPDGARAYRAAFPQAGPEELVETVYSDALFRMPSQKLAEANAVAGGTSYLFELRWVAPALGGILGACHSLDVPLAFGTLDSPASAQLIGEEPTPEAVALSRELQDAWVRFVTTGDAGWPAHRPGGHLTRVLDTESQTLPYPEQASRQIWEGHFPAPFDLS
>CP032698.1|AYG78182.1|280215_280815_+|HTH-type-transcriptional-regulator-BetI
MPKQVDHRERREAIARALWRVVEQRGVTQLTMRVVAQEAGMSLGQLQHYFASRTAMLSFAMDFASEQTSTRIRQGLEKLGDRPHPRDLLRLTLAEMLPLHADARATSRMSAAYVLEALHDEAVHEQAHRGLVMGRAHVEQLVRQAIADGHIDSGRDPATETNLLLALTGFTPLIELDVIRPQDALNAIDAHLDRLFMST
>CP032698.1|AYG78183.1|281232_282063_+|2-(acetamidomethylene)succinate-hydrolase
MTDSSSARHTARADPVHVTVWGEDNVEGPPAVFVHGILTWGDDDRYGFAAQRPLADRYRLLLMDRRGYGRSPDVERSDWAVDAEDIIGLLGSGAHLVGHAYGGVGALAAAVQRPDLIRSLTLIQPGALRPAERHPVVAQALARARTATAALPAGLTAKEFLRAATESVGMATPEATAWRLRAAASTMTELPCWDADIPLTPLSDARFPKLMISGDWEGAPEQYRKYAGEPLIACARHIAEAIGAEHLTVPGYYPHVQQPQRVNTALGKLWSGTAHA
>CP032698.1|AYG78184.1|282231_282822_-|hypothetical-protein
MSDPVPFAVPSRFDGDRDRVAVVVPGVGYSPARPLLHFARSVLLQHGWTVQELWWQIPDGFSQCTVNDRVEWVEREVTEAVDAEGGACRLLIGKSLGSLACGIAADRNIPAAWLTPVLTSDHVAAALQRATEPTLLIGGSADKLWDSRLTASLRHEVLEVPSADHGLELADDAAGSVDVLRQVVSRLDHFIGSLGH
>CP032698.1|AYG78185.1|282858_283743_-|hypothetical-protein
MTPLFGQAAWSGRARMRAAAVVTAVVLGAVGCGSGGSSDPQGGQAAQRSAGTAATPDSEKALDAPVAKGIASLTRGNLTLLAFYDPSTGRQTFGTWLPQSSEDNPWKRYSFSPDWERYTWVKDGELFVGSFTGSAVVSSYDKKPGIRIGGKPTFNGGKRAYRQPRFSADGKRIYALGNDDKVYSADPASPDQLTEEATMDPGAFFGGRSDLLWDLGADGKVIKRPSALIPRRGAQVTSPDGSKTLLSNGAGWFVKTNGAPGEPKLAFESFTDDMNQPVGNGPDPGKTLDLIGWY
>CP032698.1|AYG78186.1|284242_286066_-|hypothetical-protein
MVKAGRPQGGPKGQSEQANALANFVRALTKDFTVRELAERYKISKTSWGEYRSGAKLIHLHLLKRLVHDLVRDERTRIQRWEDAQSLHAAAVAAQRPVPPANETASDRGVTPREAVEQATATLQDTERLVHLLLGVIAGLQMQLSPTSSSPLDGTKEQPGGMAAASDLEEAESRLVQVRLVQSAVTRVRDEAATYDIDPAAVPPGAAEAGRTEEGTQSLPARYATASREAAVILLVSRAALAQQHEAVQLLSARSVQADTPRSLPSAPSPAPALAGPPRTGGGAPAESGTPRRSWQRLPVVVAALVLTATVSGAAVYTVIDLRNAKPPAAGPASSPASTPASPSTATARTPSALRSSPPSPSASPAGPAPNAPAGAPGPAAVPKTFIGTWEGEFTEPGERTLSLRRIVVREGTVGTAVAHVLTLSRTALCQSQGTVTSAGASLTIGPGTATAPSTGPCDPTGDISLRSNDADTLTWTSGSTTTTLHHAASADRAVPTPYLGTWRAQDGNDPTSSVRMTIQQGPLGQARAEFSWDGDIHHCKGVSILASTGDGLKFGPETVTASEPAGFCTQTPSRIISPPQADTMHVEWFTPPDGSQPRAFAFHRAG

Crispr_ID: CP032698_2

• CRISPR_ID: CP032698_2
• CRISPR_location: 1292394-1292591
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP032698_2

Consensus_repeat	Method
GGGTTTAGGGGCGCGGGGAACTGCGCGAGAACCGACCACGG	PILER-CR
TTAGGGGCGCGGGGAACTGCGCGA	CRISPRCasFinder

spacers of CP032698_2

>2.1|1292446|22|CP032698|PILER-CR
CCAGCCACCTGCGGCGTGCAGA
>2.2|1292520|13|CP032698|PILER-CR
CGCAGACGAAAGC
>2.3|1292421|35|CP032698|CRISPRCasFinder
CCAGCCACCTGCGGCGTGCAGACGAAAACGGGTTT
>2.4|1292480|32|CP032698|CRISPRCasFinder
GAACCGACCACGGCCCGCAGACGAAAGCGGGG
>2.5|1292536|32|CP032698|CRISPRCasFinder
GACGCGGGCACGGTCCGCAGGGTCGAGAGGGT

CRISPR arrays and Neighbor proteins around CP032698_2

CRISPR arrays

The CRISPR arrays of CP032698_2

>merge|CP032698|2|1292394-1292591|PILER-CR,CRISPRCasFinder
GGTTAAGGGGCGCGGGGAACTGCGCGACCAGCCACCTGCGGCGTGCAGACGAAAACGGGTTTTTTGGGGCGCGGGGAACTGCGCAAGAACCGACCACGGCCCGCAGACGAAAGCGGGGTTAGGGGCGCGGGGAACTGCGCGAGACGCGGGCACGGTCCGCAGGGTCGAGAGGGTTTAGGGGCGCGGGGAACTGCGCGA

>CP032698|2|1|1292394-1292548|PILER-CR
GGTTAAGGGGCGCGGGGAACTGCGCGACCAGCCACCTGCGGCGTGCAGACGA	AAACGGGTTTTTTGGGGCGCGG
GGAACTGCGCAAGAACCGACCACGGCCCGCAGACGAAAGCGGGGTTAGGGGC	GCGGGGAACTGCG
CGAGACGCGGGCACGG

>CP032698|2|2|1292397-1292591|CRISPRCasFinder
TAAGGGGCGCGGGGAACTGCGCGA	CCAGCCACCTGCGGCGTGCAGACGAAAACGGGTTT
TTTGGGGCGCGGGGAACTGCGCAA	GAACCGACCACGGCCCGCAGACGAAAGCGGGG
TTAGGGGCGCGGGGAACTGCGCGA	GACGCGGGCACGGTCCGCAGGGTCGAGAGGGT
TTAGGGGCGCGGGGAACTGCGCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG79062.1|1294015_1294783_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG79058.1|1288649_1289324_-|hypothetical-protein	unknown	unknown	gnl|CDD|273662
CP032698.1|AYG79066.1|1298656_1299031_-|hypothetical-protein	unknown	unknown	gnl|CDD|380093
CP032698.1|AYG79065.1|1297338_1298532_-|NADH-dehydrogenase-like-protein	unknown	unknown	gnl|CDD|224172
CP032698.1|AYG79055.1|1283648_1285022_+|Alanine--anticapsin-ligase	unknown	unknown	gnl|CDD|223516
CP032698.1|AYG79060.1|1290719_1292099_-|putative-amino-acid-permease-YhdG	unknown	unknown	gnl|CDD|129987
CP032698.1|AYG79067.1|1299315_1299555_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG79057.1|1287027_1288410_+|hypothetical-protein	unknown	unknown	gnl|CDD|349949
CP032698.1|AYG79052.1|1279659_1280976_+|2-methylisoborneol-synthase	unknown	unknown	gnl|CDD|173835
CP032698.1|AYG79056.1|1285018_1287028_+|Phosphoenolpyruvate-synthase	unknown	unknown	gnl|CDD|376527
CP032698.1|AYG79059.1|1289599_1290559_-|Putative-ketoacyl-reductase	unknown	unknown	gnl|CDD|187632
CP032698.1|AYG79070.1|1302694_1303726_-|Serine/threonine-protein-kinase-PknH	unknown	unknown	gnl|CDD|270916
CP032698.1|AYG79064.1|1296424_1297342_-|ECF-RNA-polymerase-sigma-factor-SigJ	unknown	unknown	gnl|CDD|236600
CP032698.1|AYG79069.1|1301396_1302611_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG79063.1|1295033_1296395_+|hypothetical-protein	unknown	unknown	gnl|CDD|239481
CP032698.1|AYG79054.1|1281962_1283306_-|hypothetical-protein	unknown	unknown	gnl|CDD|379177
CP032698.1|AYG79061.1|1292668_1293910_+|O-mycaminosyltylonolide-6-deoxyallosyltransferase	unknown	unknown	gnl|CDD|340817
CP032698.1|AYG79051.1|1278135_1279548_+|Major-membrane-protein-I	unknown	unknown	gnl|CDD|237999
CP032698.1|AYG79068.1|1299652_1301005_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
CP032698.1|AYG79053.1|1280981_1281875_+|Geranyl-diphosphate-2-C-methyltransferase	unknown	unknown	gnl|CDD|215135

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG79058.1|1288649_1289324_-|hypothetical-protein	gnl|CDD|273662	TIGR01509, HAD-SF-IA-v3, haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED. This model represents part of one structural subfamily of the Haloacid Dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The superfamily is defined by the presence of three short catalytic motifs. The subfamilies are defined based on the location and the observed or predicted fold of a so-called "capping domain", or the absence of such a domain. Subfamily I consists of sequences in which the capping domain is found in between the first and second catalytic motifs. Subfamily II consists of sequences in which the capping domain is found between the second and third motifs. Subfamily III sequences have no capping domain in either of these positions. The Subfamily IA and IB capping domains are predicted by PSI-PRED to consist of an alpha helical bundle. Subfamily I encompasses such a wide region of sequence space (the sequences are highly divergent) that representing it with a single model is impossible, resulting in an overly broad description which allows in many unrelated sequences. Subfamily IA and IB are separated based on an aparrent phylogenetic bifurcation. Subfamily IA is still too broad to model, but cannot be further subdivided into large chunks based on phylogenetic trees. Of the three motifs defining the HAD superfamily, the third has three variant forms: (1) hhhhsDxxx(x)D, (2) hhhhssxxx(x)D and (3) hhhhDDxxx(x)s where _s_ refers to a small amino acid and _h_ to a hydrophobic one. All three of these variants are found in subfamily IA. Individual models were made based on seeds exhibiting only one of the variants each. Variant 3 (this model) is found in the enzymes beta-phosphoglucomutase (TIGR01990) and deoxyglucose-6-phosphatase, while many other enzymes of subfamily IA exhibit this variant as well as variant 1 (TIGR01549). These three variant models were created with the knowledge that there will be overlap among them - this is by design and serves the purpose of eliminating the overlap with models of more distantly related HAD subfamilies caused by an overly broad single model. [Unknown function, Enzymes of unknown specificity].	0.0018166
CP032698.1|AYG79066.1|1298656_1299031_-|hypothetical-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	4.30671e-29
CP032698.1|AYG79065.1|1297338_1298532_-|NADH-dehydrogenase-like-protein	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	5.28066e-69
CP032698.1|AYG79055.1|1283648_1285022_+|Alanine--anticapsin-ligase	gnl|CDD|223516	COG0439, AccC, Biotin carboxylase [Lipid metabolism].	2.51386e-27
CP032698.1|AYG79060.1|1290719_1292099_-|putative-amino-acid-permease-YhdG	gnl|CDD|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	6.10211e-49
CP032698.1|AYG79070.1|1302694_1303726_-|Serine/threonine-protein-kinase-PknH	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	4.69158e-111
CP032698.1|AYG79057.1|1287027_1288410_+|hypothetical-protein	gnl|CDD|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	2.40169e-10
CP032698.1|AYG79052.1|1279659_1280976_+|2-methylisoborneol-synthase	gnl|CDD|173835	cd00687, Terpene_cyclase_nonplant_C1, Non-plant Terpene Cyclases, Class 1. This CD includes terpenoid cyclases such as pentalenene synthase and aristolochene synthase which, using an all-trans pathway, catalyze the ionization of farnesyl diphosphate, followed by the formation of a macrocyclic intermediate by bond formation between C1 with either C10 (aristolochene synthase) or C11 (pentalenene synthase), resulting in production of tricyclic hydrocarbon pentalenene or bicyclic hydrocarbon aristolochene. As with other enzymes with the 'terpenoid synthase fold', they have two conserved metal binding motifs, proposed to coordinate Mg2+ ion-bridged binding of the diphosphate moiety of FPP to the enzymes. Metal-triggered substrate ionization initiates catalysis, and the alpha-barrel active site serves as a template to channel and stabilize the conformations of reactive carbocation intermediates through a complex cyclization cascade. These enzymes function in the monomeric form and are found in fungi, bacteria and Dictyostelium.	8.48037e-88
CP032698.1|AYG79056.1|1285018_1287028_+|Phosphoenolpyruvate-synthase	gnl|CDD|376527	pfam01326, PPDK_N, Pyruvate phosphate dikinase, PEP/pyruvate binding domain. This enzyme catalyzes the reversible conversion of ATP to AMP, pyrophosphate and phosphoenolpyruvate (PEP).	2.58033e-37
CP032698.1|AYG79059.1|1289599_1290559_-|Putative-ketoacyl-reductase	gnl|CDD|187632	cd05374, 17beta-HSD-like_SDR_c, 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. 17beta-hydroxysteroid dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	7.4611e-56
CP032698.1|AYG79064.1|1296424_1297342_-|ECF-RNA-polymerase-sigma-factor-SigJ	gnl|CDD|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	3.85948e-112
CP032698.1|AYG79063.1|1295033_1296395_+|hypothetical-protein	gnl|CDD|239481	cd03386, PAP2_Aur1_like, PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin.	2.78111e-22
CP032698.1|AYG79054.1|1281962_1283306_-|hypothetical-protein	gnl|CDD|379177	pfam13426, PAS_9, PAS domain.	2.42272e-11
CP032698.1|AYG79061.1|1292668_1293910_+|O-mycaminosyltylonolide-6-deoxyallosyltransferase	gnl|CDD|340817	cd03784, GT1_Gtf-like, UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.	1.04422e-50
CP032698.1|AYG79051.1|1278135_1279548_+|Major-membrane-protein-I	gnl|CDD|237999	cd00038, CAP_ED, effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels.	6.46109e-19
CP032698.1|AYG79068.1|1299652_1301005_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	1.71165e-08
CP032698.1|AYG79053.1|1280981_1281875_+|Geranyl-diphosphate-2-C-methyltransferase	gnl|CDD|215135	PLN02244, PLN02244, tocopherol O-methyltransferase.	4.06446e-17

Protein sequences

>CP032698.1|AYG79060.1|1290719_1292099_-|putative-amino-acid-permease-YhdG
MQTEQPAPAAPDAPAALKRALGTPLLYFFILGDVLGAGVYVLIGQVASKSGGAVWVPLAVALGLALLTAASYAELATKYARAGGASYYATLAYGPFVGFFTGFCMLAAGIVSVAALARGFGGTYLTAFVNLPVALVAVLFLGALALLNARGISESTRANVVATVIETSGLLLIIGLGVWLVVRGDGDVGRLTQLGTPERGPMAAALSGAVLAYYSFVGFETSVNVAEETRNPRRAYPRALFGALGTAGLIYAAVGAAASAAVPTGVLAGSDGPLLEVVRAAGGVPGSLFSAIALVAVANGALLTGIMCSRLAFGMARERLLPSFLTRVLPRRRTPWAAIATTTALSLLLALTGDIETLAATLVLLLLVVFFTVNTAVLVLRRRDTSGNPDHFRAPAVIPVLGALSCVVLATQIDHEVWLRGLVLLAVGAALGLVSAKVSRRTAAPSEATAAPGGGPTAP
>CP032698.1|AYG79059.1|1289599_1290559_-|Putative-ketoacyl-reductase
MNPRPHRFAGRTALVTGSSRGLGLLIARELTARGCRVMLCARGAEGLAAAERKLRATGAEVASCACDITEPDAPQRLLDAVHERFGPLDILVNSAGIIQVGPVETFEEKDFREAMETMLFSPLRLALAALPDLRASGAGTLVTVSSIGGRIAAPHLLPYVTAKFAAAGFSQGLRAELAGSGVSVTTVFPGLMRTGSHTAAKFFGRPGAEYGWFGAAATLPLLSMDAGRAARAVVRAAERGRPELVLTPAAKVAVRLQGVAPASMARLLSLTDRALPGPGDHPRRDVPGAEAAKQSRLPRWVTTLGDRAGRRLGEPRPHN
>CP032698.1|AYG79058.1|1288649_1289324_-|hypothetical-protein
MARCRTTMGDTAMHLSATRGLRRTSLALGAALASTLLCATVSGAAPLGASGLADPGHVASARAQRACPVVYFDLGETLVHTADDGSVGYLPGAAAYLRALREHHITIGLITNVPPSWGATDAERAARLKKEVDATWRDSTPFAWGDFGDRILTPRTEAERKPAPALWRRAMARSGSCRLVYEAETAQEVQVAAEQGFVPYQIGQPHRPEFLPVGLVALLGRLPR
>CP032698.1|AYG79057.1|1287027_1288410_+|hypothetical-protein
MPRLAPRTHEGAGLTDKARRIIRLNYGFQLLFNLLWWMPVFYAYQKEAGLSDGQIFGIQSIYYVAFCLFEIPTGLIADRIGARNCLRAGAVVMTAANLAPVVSASYTGFLLHFLAIAVGRSLTSGAASAYLYDGLRAEKCGEHYLKAEGTARALGLAAKVVCWPLVGPLMAVAHTAPYVLSAASAAGSLVCAVALPRLAGAEDGARSPGRSTAGRGGGAFLRDAGAALRCVASSRWLGLVMVQGVAVFTLSRICQVNLFQPILLDHGIGEASSGGVLAAMTVAEAVASARPQWLSRRLTPVAWVSLLSLALAGTLAAMTVGGPWLVIALLCLFAAATGFVYPVQRKLVNDAIPANAPRATLLSIESIVDRGVCALAAIAVGAYVSAGHLDTLLLHSALATALLLGAIHLLLRSGVVRHDRAPAGAPTDARAALAADADGQDAGDRLGRAEGARSGPPSDT
>CP032698.1|AYG79056.1|1285018_1287028_+|Phosphoenolpyruvate-synthase
MTAQLFAGAAEPATDRTVIGENLSLPLFRTLSGVLAGHPYLKVVVDRAEHTWHLLDTAAHPFHVNYIATRVLGMELADLDAELDAFNASVYMDPARRFLLGVLSLHTNEDSEGRERTFLVLETTEADTMNGQLLKFFYAFVRERVDGRLPLLLKPANHGQEEELAAISELRVPRILSHELFGSRVRTPLNPGDATGRLRFFRTHEEYAAAEGELGWADIVAMPCLPDDVPRVAGFLNTAPITPLSHTNVLASGWGIPNAIVRDLDELVEKDALDGAWVRYRVSEEEISLERLGSEPELRAPAWHQQRIRLEPPLLEDAPVLSLHRLRAADSDRYGTKAANLGELHHVLDSRTADLTVFYGRPRPPRDDLYGHLASRLGLKDPSLAELRARAADFVASTVGAPEGVALPFSLQQHFLASSPALQQGIGKLKMALELDATDVLDSLCLQLQQLIRHTPIPDSVTRQISQAFPTAPASRGRLVVRSSSNAEDLPGFSAAGVYDSVTTVHGTGQLLDAVRQVWASLVSPRSVRLRHQVGISLDDTYMGVIIQEYVPASLGGVLVTCDPTRRADFRNVYLNCSPGSPEQVVDGSVLPQQYLYNVVEGGGRTVALGSWGDGLPAATRARLADLSLTGRLLQSHFSDTDVDKPLDIEWLMTERGDFRLVQIRPYAL
>CP032698.1|AYG79055.1|1283648_1285022_+|Alanine--anticapsin-ligase
MSKVLLVHAKGGPPLGHVLSRTAARAEVHLLALSALPPVVADSAHRLCASVVTPAEAQRSDLVSLIVSRARAVGADAVLTFSEYAVVAVAEACEALGLAGAGDAAALARDKRLMRRTWREHGLSQPEFRAVTREADLHEAAGVLSFPLLLKAAWSAGSTAHQIIRSPQELSGAWHRSREVMAESAQLGYAELHVAEAQGHFVVEEIVTGTASDWFDEPGWGDYVSVEGAVADGTFHPVCLSGRMPTVEPFTERAGITPALLSQDAQDRVVALARQAVDALGLRDCGTHTEIKLGADGRMWLIETAARFGGAMTVPQIEDVFGLDLVGMLVDQLLGRPVHWPEQALTPAQARGAAGSLVVLAVDGDGEAWRERKIWDFPSVAKEVPLSRGSELSVVAESSLPDGQVVPVYDPAGGANTMAALCLLSATDARTVLRDFETLVDALPRVLPVAQPEEVSA
>CP032698.1|AYG79054.1|1281962_1283306_-|hypothetical-protein
MRQPVAYELYTDGETAVDDSSLKALLEHLPVFWWEVDEPWQVRERGGGAFADAGTAQRFLDRMRQELPAPGAPPRKGRWQARFDDRTFDVSWPLDESSAHGRTRGLAVEVDARPETPRQYAAFAGLVNLAPAAAFIRDSEGRYVWANHAYAHLYGAVPEELVGKYIEDFDAPAESLQFRALDQEILTRGTPVRHTLDYRRPDGSAGQALGHRFPVRENGRTCVAGIYVDVTDHLRAKLKRQEAEDDLRALRDHSGLPCALLSANGRVVEASAAAAELFALSLPDLVGRRAHTLLAPEPSLDRLHRRWHGLIARRTRRVETSAVLVDSQGRQRRAQLHLTTVGQSTTRARHVWAVVTHQSLAHEAHPSLTAAQIRILSLLAAGSSNGDIATSLNLSRQTVDYHLSRLRELLGAGTRPALGARAYVLGILAPRAWPPRSATAAHPLSAV
>CP032698.1|AYG79053.1|1280981_1281875_+|Geranyl-diphosphate-2-C-methyltransferase
MDSSVTSTELTATDTSLFIPGPVTPYQGDIARYWDGEARPVNLRLGDVDGLYHHHYGIGEVDHAALGDAQDSEAEKKLITELHRLESAQAELLLSHLGDIGSDDTLVDAGCGRGGSMVMAHERFGCRVEGVTLSAKQAAFANGRARELRIEDRVRARVCNMLSMPFETGQAAGSWNNESSMYVDLHDLFAEHSRVLKVGGRYVTITGCWNPRYGQPSKWVSQINAHFECNIHSRREYLRAMADNRLVPQAVIDLTPDTLPYWELRATSSLVTGIEEAFINSYRDGSFQYVLIAADRV
>CP032698.1|AYG79052.1|1279659_1280976_+|2-methylisoborneol-synthase
MPAPELTPPQSSLPEAGAHFGAYALADAATRARDVLAATGAPPRALPGAPPGPPPGLPTVAATSLPDVPAVEPPPLSPDVDRLLRGPSGLGTAGLRLTLPQERPAPPKPSAPQGAAIPGLYHHPVPEPDPARVEEVSRRIKSWAMDEVSLYPDDWEEEFDGFSVGRYMVACHPDAPSVDHLMLATRLMVAENAVDDCYCEDHGGSPVGLGERLLLAHTALDPLHTTREYQPQWAESLHSDAPRRAYHSAMDYFVQSASASQADRYRHDMARLHLGYLAEAAWAQEDRVPEVWEYLAMRQFNNFRPCPTITDTVGGYELPADLHAQPAMQRVIALAGNATTIVNDLYSYTKELDAPGRHLNLPVVIAEREGISDREAYLKSVEVHNDLMHDFETEAAALAADCPVPSVQRFLRGVAAWVDGNHYWHRTNTYRYSLPDFW
>CP032698.1|AYG79051.1|1278135_1279548_+|Major-membrane-protein-I
MTVDSSPDARLETPRQSSLGTAAARNLTHTTKSAPQMQEISSRWLLRMLPWVEATGGVYRVNRRLTYTVGDGRVEFIQSGADVRVIPRELGELALLRGFDDVEVLTAIADRCVQRDFAVGETLVERGAPADRLYLIAHGRISQTSVGGYGDELALDVLGDGDRFGDEALLDEDARWEHTAVAETSGTLLTLSRADFAAAVAAAPNLREHVERFASLPHQRQNHKGEAEIAMSAGHHGEQELPGAFVDYESKPREYELSVAQTILRVHTRVADLYNGPMNQTKEQLRLTIEALRERQEYELIHNRDFGLLHNVDFKQRIQPRTGPPTPDDLDELLCRRRGSRFYLAHPKAIAAIGRELNARGLRPDQVEVEGELVQAWRGVPILPCDKIPISQEKTSSIFIMRTGADDQGLIGLRQTGLPDEYEPGLSVRFMGLDEKAITSYLVSTYYSAAILVPDAVGVLENVQVARWPR
>CP032698.1|AYG79061.1|1292668_1293910_+|O-mycaminosyltylonolide-6-deoxyallosyltransferase
MRVLIVTAGTWGDVAPYTGLGVRLRTEGHEVALATHERFRQAVRAHGLAFRPLPVDPRQELASASGQGLARAVSPPVALARVARMARAFMPALATGVADAVREGADVLLSSTLTDPMCAVLGEALGVANLGVYVQPIEPTAAFPPVVVGARSFGAYGNRLGARVLRAVTDRIFGPAVGGLRHELGLPARRLSGPLGLPPGRTVLHGFSPRVVPRPADWPEGHRVCGYWWPPTPPDWRPEPRLLDFLAAGPPPVLAGFGSFVESDAERLSTLLADALRRAKVRGIVQAGWSGLRVESDDVLTVREVPHAWLFPKTAAVVHHAGAGTTAAALRAGVPAVPVPVQLDQHFWAGRVHALGVATRPLHYQRLTASRLADAITAATGAPALRARARRVARELAGEDGAGAVAATLERLA
>CP032698.1|AYG79062.1|1294015_1294783_+|hypothetical-protein
MAPDGKVTRRGDGGVTLNGEAVEPDYLMSVPGPRGLVTNGKEGGTGKGGFGVEGGWQSSRVTPPGADSLLDYDTVINGVRREPNGRVVGAVGSHLIANWRPRGTSATRGLSAIHDLATGAVQATAACDADTTEYDADLPRPTNLAEVRPAVSPNGRYLGKGGAVYDLTTGRGICTGGESDAKKITLNAVGDDGTAYGVAGEDKPRTPVAVSARAGSAQPLPKAMSTPDAIAQGAGVFVTYAGTDTLRLIVLRPRK
>CP032698.1|AYG79063.1|1295033_1296395_+|hypothetical-protein
MPRISRISRTLGSVPGSRPRLILWATAGAATLGFLIALEIVARRYGGVPGPITLQARELIFPPKPGPLYGGLALMMVVLTWRQRFVAAAAAIGIDAVFVLARWAAHVKVPADHFFGNGALWAMLGCAVFAITRRTGEERALLLKGVGLGLLLVTGRKTGDAWLLITSKTRPTVLDPYVALADHALGNPSWAAGRALEAIGPAGTQVLAWVYAQLAVAAIVVALYQLRNVASERRFPRHHLVRTFLVIGLLGPAVYMIFPVVGPVFAYGPGASGTGGVQWAVANLWPHTPPPIAVPHAVPYDGITPRNCMPSLHTAWATAIFIHTRRGPRVLRYAGAFWLIATLSATLGFGYHYGVDLVAGVVFALTVEAALRTLDRGWDRSGVRLVGYGTAVFGALLVAYAFLPMRMATHPWLFGPLVLLAMASVIHRYVRTTRAWDPQAAPLLRPEPRPEPV
>CP032698.1|AYG79064.1|1296424_1297342_-|ECF-RNA-polymerase-sigma-factor-SigJ
MTQPQQADADQLAFQQYRTLLFSVAYRILGTAADAEDVVQDAWLKWSAADRSQVADPKAYLTRIISNLAMELLRSTRHQRETYVGPWLPEPILTGPDTADGVVAADSVSMALLVVLETLSPLERAVFVLKEVFAFSYGEIAQAVERSEPAVRQAAHRAREHVQARRPRFATDRTRQHDVAERFFAAATGGDINTLMELLSPDVTLWTDGGGKVRQALKPVIGLETVARWFAALGSTSYQGVEPGQMRAELTSINGGPGLVFQGPDRVIATMTFDFDAEGRISAIHNVANPDKLHAVADGTRHELT
>CP032698.1|AYG79065.1|1297338_1298532_-|NADH-dehydrogenase-like-protein
MNTTTAQQHEVLVLGAGYAGLGAAIQLAVRTKKRGNVRVTLVNPYDTFTERLRLHMTATGQETAEMNIAEMLDGTGAEFVRGWVTAVDAAAKTVRIDDDRVLRYDTLVYGLGSIADTTTVPGVDDHAYTFNSPEDAAVLADRLARLDGGTVVVGGSGLTGVEAAAEIAERHPELHVVLLGRQEPGASMHPKAKAHVDAALARLGVEVRAGVEVTKVLPDRVELADGTGIDAAATLWTSGTRVSPLAAGAGLTVDERGRVVTDTALRSVSHPDVYAVGDAAAIRQGYGVMHGTCQGGMPTGVHAALSILRVLAGKEPKPFRFGYYHTPVSLGRNDGVVQFTHPDDSPRRIVLTGKRAAKYKETVSAAPWPTFARMKKMPVSGAFWPHGGRYTRIRSAK
>CP032698.1|AYG79066.1|1298656_1299031_-|hypothetical-protein
MIRKLQAVALDCADPVRLAEFYAELLGGRVTADPDDSDWVEVGGFEGTPLACQRVEGYQPPQWPGQERPQQLHLDFDVDDLDAEEKRALALGATLLERTDEVRPGANWRVYADPAGHPFCLCLH
>CP032698.1|AYG79067.1|1299315_1299555_-|hypothetical-protein
MRMRTTLAAGALAVAAILGSTGTALADGYDNHHSGGGSGACGEFAAAIHGNAAWGNGCKHSQWQGMMPGHGHQGGFNSF
>CP032698.1|AYG79068.1|1299652_1301005_-|hypothetical-protein
MSVEPPSSGRPTGPPSGPLSGPSQPSPSGPGDTQAGATRADSTPPPGAERPSGPPGGGPPSGPGGDGHGDGPGGSGAGSGGSQGPSRPWWKSAPRVAALSAAVVAAAVLAVVLTRPDGSSGGGSPEAGGEVLLQPAAKSGPDPFTESTARGDSRPPSPLALPSSSASANVTRGVDGSAPGLYGGTQNVASCDVEKQVGALQKDPAKNKAFASVLDIQPSGVPGYLRALTPVQLRLDTRVTNHGYRDGAPTSYQSVLQAGTAVLVDDHGVPRVRCACGNPLLPPVAQKGTPKRTGEAWPGYRPSNVVVVAPAIQVVNKFVVYDPDGGAWFERHKGDTGTGDTKTKPPVTTPSSPTSESPSISPSAGESSSTTSPSPCVSLSPGTSSEKRCPHTSAPPSAPPSSPSSQPPSSPASQPPSSPASQPPSSAMEQSPALSEPASPPSSAGTGGGS
>CP032698.1|AYG79069.1|1301396_1302611_+|hypothetical-protein
MAVLASLVAMAVVAALGLWAAGATDLPGGAFPSVVAAVVVMAVGGSVGLSGDAGAIAETNAGLSVLPLSVSLAGALAIAAGFLRPLRHRAVADAKELAGWAGRIAVLWLLLLVGLGLLARHRFRIPLGDGPAADIGDALDSSPEVGFETDVPLTLLFGLLWLAGVLIVVLLVSRAAPLPARLLRFQESVRPAAFAMVVLLLAYVALGFVIGLGVVVTRGHAAATLAVLLLGLPNLVWLAFTLGLGASWEGRVDGPFGLPMPQVLDAVLRRPDDTTLSLNTLADHDGRVWWLLVVAAVLVLGAAFLMAARSPVRMRAWQHAVHMAVALTLTVLAVCLLAGVSAHYGLSLLGIGDLGGGLSGLVELRPVLWRALVLALAWGLVSGFLGGLFARRVRRRGKVEVDPG
>CP032698.1|AYG79070.1|1302694_1303726_-|Serine/threonine-protein-kinase-PknH
MAPAQREPAPREPAPSPHSGRPSELIGQQIAGYRVEGEIGRGGMAVVYRAKDLRLDRTVALKLLAPELARNDTFRKRFTHESRVAAAIEHPHIVPVFEAGETDGVLYIAMRYVPGRDLRHLLDHAGPLSVEAALRIATQVASALDAAHDHGLVHRDVKPGNILVAKGTDSDHPEHAYLTDFGLTKKSLSLTGFTTVGQFVGTLDYVAPEQISGRPVDGRCDVYSLACVVYETMAGGPPFQRDDDIALLWAHQYDEPPRLTEKRPGVAAALDPVLARALAKSPEDRYGSCLAFAAALRAAATGGPASGHPATRVDGHVVGAPADPGAPPEPPQWARPVFRDLTG

Crispr_ID: CP032698_3

• CRISPR_ID: CP032698_3
• CRISPR_location: 1534829-1534908
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_3

Consensus_repeat	Method
TTGCGCAGTTCCCCGCGCCCCCA	CRISPRCasFinder

spacers of CP032698_3

>3.1|1534852|34|CP032698|CRISPRCasFinder
AAACCAGACGTCGACTGCGGACCGTGCCCGCGAC

CRISPR arrays and Neighbor proteins around CP032698_3

CRISPR arrays

The CRISPR arrays of CP032698_3

>merge|CP032698|3|1534829-1534908|CRISPRCasFinder
TTGCGCAGTTCCCCGCGCCCCCAAAACCAGACGTCGACTGCGGACCGTGCCCGCGACTCGCGCAGTTCCCCGCGCCCCCA

>CP032698|3|3|1534829-1534908|CRISPRCasFinder
TTGCGCAGTTCCCCGCGCCCCCA	AAACCAGACGTCGACTGCGGACCGTGCCCGCGAC
TCGCGCAGTTCCCCGCGCCCCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG79273.1|1534235_1534649_-|hypothetical-protein	unknown	unknown	gnl|CDD|239527
CP032698.1|AYG79272.1|1531956_1534029_-|Penicillin-binding-protein-1F	unknown	unknown	gnl|CDD|273955
CP032698.1|AYG79279.1|1539885_1540677_+|Peptidoglycan-N-acetylglucosamine-deacetylase	unknown	unknown	gnl|CDD|213022
CP032698.1|AYG79268.1|1527085_1529143_-|hypothetical-protein	unknown	unknown	gnl|CDD|340391
CP032698.1|AYG79264.1|1525099_1525669_-|hypothetical-protein	unknown	unknown	gnl|CDD|376570
CP032698.1|AYG79274.1|1535306_1535789_-|hypothetical-protein	unknown	unknown	gnl|CDD|380338
CP032698.1|AYG79281.1|1541811_1542603_-|hypothetical-protein	unknown	unknown	gnl|CDD|238870
CP032698.1|AYG79271.1|1531291_1531939_+|Transcriptional-regulatory-protein-DegU	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG79275.1|1535922_1536441_-|hypothetical-protein	unknown	unknown	gnl|CDD|379112
CP032698.1|AYG79282.1|1542817_1544011_+|hypothetical-protein	unknown	unknown	gnl|CDD|350610
CP032698.1|AYG79283.1|1544088_1546188_-|Bifunctional-alpha-galactosidase/sucrose-kinase-AgaSK	unknown	unknown	gnl|CDD|307952
CP032698.1|AYG79267.1|1526643_1527078_-|Serine-protease-inhibitor	unknown	unknown	gnl|CDD|367422
CP032698.1|AYG79270.1|1530047_1531307_+|Sensor-histidine-kinase-DesK	unknown	unknown	gnl|CDD|226951
CP032698.1|AYG79280.1|1540717_1541761_+|hypothetical-protein	unknown	unknown	gnl|CDD|187575
CP032698.1|AYG79276.1|1536524_1536968_-|hypothetical-protein	unknown	unknown	gnl|CDD|367833
CP032698.1|AYG79266.1|1526269_1526641_-|hypothetical-protein	unknown	unknown	gnl|CDD|283084
CP032698.1|AYG79269.1|1529424_1529856_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG79265.1|1525671_1526292_-|hypothetical-protein	unknown	unknown	gnl|CDD|225138
CP032698.1|AYG79277.1|1537014_1538220_-|putative-L-ascorbate-6-phosphate-lactonase-UlaG	unknown	unknown	gnl|CDD|293841
CP032698.1|AYG79278.1|1538493_1539054_+|Ribosomal-protein-serine-acetyltransferase	unknown	unknown	gnl|CDD|379112

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG79273.1|1534235_1534649_-|hypothetical-protein	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	5.36621e-28
CP032698.1|AYG79272.1|1531956_1534029_-|Penicillin-binding-protein-1F	gnl|CDD|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	5.40209e-140
CP032698.1|AYG79279.1|1539885_1540677_+|Peptidoglycan-N-acetylglucosamine-deacetylase	gnl|CDD|213022	cd10917, CE4_NodB_like_6s_7s, Catalytic NodB homology domain of rhizobial NodB-like proteins. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes many rhizobial NodB chitooligosaccharide N-deacetylase (EC 3.5.1.-)-like proteins, mainly from bacteria and eukaryotes, such as chitin deacetylases (EC 3.5.1.41), bacterial peptidoglycan N-acetylglucosamine deacetylases (EC 3.5.1.-), and acetylxylan esterases (EC 3.1.1.72), which catalyze the N- or O-deacetylation of substrates such as acetylated chitin, peptidoglycan, and acetylated xylan. All members of this family contain a catalytic NodB homology domain with the same overall topology and a deformed (beta/alpha)8 barrel fold with 6- or 7 strands. Their catalytic activity is dependent on the presence of a divalent cation, preferably cobalt or zinc, and they employ a conserved His-His-Asp zinc-binding triad closely associated with the conserved catalytic base (aspartic acid) and acid (histidine) to carry out acid/base catalysis. Several family members show diversity both in metal ion specificities and in the residues that coordinate the metal.	2.19084e-74
CP032698.1|AYG79268.1|1527085_1529143_-|hypothetical-protein	gnl|CDD|340391	cd00075, HATPase, Histidine kinase-like ATPase domain. This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.	4.49029e-14
CP032698.1|AYG79264.1|1525099_1525669_-|hypothetical-protein	gnl|CDD|376570	pfam01590, GAF, GAF domain. This domain is present in cGMP-specific phosphodiesterases, adenylyl and guanylyl cyclases, phytochromes, FhlA and NifA. Adenylyl and guanylyl cyclases catalyze ATP and GTP to the second messengers cAMP and cGMP, respectively, these products up-regulating catalytic activity by binding to the regulatory GAF domain(s). The opposite hydrolysis reaction is catalyzed by phosphodiesterase. cGMP-dependent 3',5'-cyclic phosphodiesterase catalyzes the conversion of guanosine 3',5'-cyclic phosphate to guanosine 5'-phosphate. Here too, cGMP regulates catalytic activity by GAF-domain binding. Phytochromes are regulatory photoreceptors in plants and bacteria which exist in two thermally-stable states that are reversibly inter-convertible by light: the Pr state absorbs maximally in the red region of the spectrum, while the Pfr state absorbs maximally in the far-red region. This domain is also found in FhlA (formate hydrogen lyase transcriptional activator) and NifA, a transcriptional activator which is required for activation of most Nif operons which are directly involved in nitrogen fixation. NifA interacts with sigma-54.	1.2126e-10
CP032698.1|AYG79274.1|1535306_1535789_-|hypothetical-protein	gnl|CDD|380338	cd02208, cupin_RmlC-like, RmlC-like cupin superfamily. This superfamily contains proteins similar to the RmlC (dTDP (deoxythymidine diphosphates)-4-dehydrorhamnose 3,5-epimerase)-like cupins. RmlC is a dTDP-sugar isomerase involved in the synthesis of L-rhamnose, a saccharide required for the virulence of some pathogenic bacteria. Cupins are a functionally diverse superfamily originally discovered based on the highly conserved motif found in germin and germin-like proteins. This conserved motif forms a beta-barrel fold found in all of the cupins, giving rise to the name cupin ('cupa' is the Latin term for small barrel). The active site of members of this superfamily is generally located at the center of a conserved barrel and usually includes a metal ion. The different functional classes in this superfamily include single domain bacterial isomerases and epimerases involved in the modification of cell wall carbohydrates, two domain bicupins such as the desiccation-tolerant seed storage globulins, and multidomain nuclear transcription factors involved in legume root nodulation.	0.000316655
CP032698.1|AYG79281.1|1541811_1542603_-|hypothetical-protein	gnl|CDD|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	3.39661e-69
CP032698.1|AYG79271.1|1531291_1531939_+|Transcriptional-regulatory-protein-DegU	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.6201e-40
CP032698.1|AYG79275.1|1535922_1536441_-|hypothetical-protein	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	8.60664e-30
CP032698.1|AYG79282.1|1542817_1544011_+|hypothetical-protein	gnl|CDD|350610	cd14728, Ere-like, Erythromycin esterase and succinoglycan biosynthesis related proteins. This group contains erythromycin esterase, which shares conserved active site residues of the Tiki/TraB family. Erythromycin esterases (EreA and EreB) disrupt erythromycin via the hydrolysis of the macrolactone ring. A critical catalytic histidine acts as a general base in the activation of a water molecule. Macrolides act by inhibiting bacterial protein synthesis by binding at the exit tunnel of ribosomal subunit 50s, blocking the translation of the polypeptide. Erythromycin esterase, typically found in integrons and transposons, confers antibiotic resistance through the disruption of the drug ring structure. EreB substrate profile is substantially broader than that for EreA, being able to also metabolize semisynthetic derivatives such as azalide azithromycin.	5.33565e-60
CP032698.1|AYG79283.1|1544088_1546188_-|Bifunctional-alpha-galactosidase/sucrose-kinase-AgaSK	gnl|CDD|307952	pfam02065, Melibiase, Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.	2.40503e-141
CP032698.1|AYG79267.1|1526643_1527078_-|Serine-protease-inhibitor	gnl|CDD|367422	pfam03259, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	1.42719e-22
CP032698.1|AYG79270.1|1530047_1531307_+|Sensor-histidine-kinase-DesK	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.15605e-36
CP032698.1|AYG79280.1|1540717_1541761_+|hypothetical-protein	gnl|CDD|187575	cd05265, SDR_a1, atypical (a) SDRs, subgroup 1. Atypical SDRs in this subgroup are poorly defined and have been identified putatively as isoflavones reductase, sugar dehydratase, mRNA binding protein etc. Atypical SDRs are distinct from classical SDRs. Members of this subgroup retain the canonical active site triad (though not the upstream Asn found in most SDRs) but have an unusual putative glycine-rich NAD(P)-binding motif, GGXXXXG, in the usual location. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.05531e-68
CP032698.1|AYG79276.1|1536524_1536968_-|hypothetical-protein	gnl|CDD|367833	pfam04134, DUF393, Protein of unknown function, DUF393. Members of this family have two highly conserved cysteine residues near their N-terminus. The function of these proteins is unknown.	4.51379e-19
CP032698.1|AYG79266.1|1526269_1526641_-|hypothetical-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	8.22677e-33
CP032698.1|AYG79265.1|1525671_1526292_-|hypothetical-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	5.00431e-43
CP032698.1|AYG79277.1|1537014_1538220_-|putative-L-ascorbate-6-phosphate-lactonase-UlaG	gnl|CDD|293841	cd16283, RomA-like_MBL-fold, Enterobacter cloacae RomA and related proteins; MBL-fold metallo hydrolase domain. Derepression of the romA-ramA locus results in a multidrug-resistance phenotype. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	1.92426e-71
CP032698.1|AYG79278.1|1538493_1539054_+|Ribosomal-protein-serine-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.17073e-26

Protein sequences

>CP032698.1|AYG79273.1|1534235_1534649_-|hypothetical-protein
MMDADAAQTVLDSTPFAPWWGFRVDAVKEGWARVSLPRRPELFRPGGVLQGGCAMTLADVTCWIAIMSLFGEDDPSVTQQMTTSFLGPARTDLVCESTIVRPGRLIVYGTAETRDTAGRLVSHHTLTYVRPPRPAAD
>CP032698.1|AYG79272.1|1531956_1534029_-|Penicillin-binding-protein-1F
MFRRMHSPRSGPAGSLFTRILRFLGVSVLAGALAAGIALPVAGGLGVGAKSAAESFNGLPDAFKAPPLSQASQIYDADGGLIATVYDRDRTVISGDHIAPVMRTALIDIEDNRFYQHGAADLQGVLRALNKNAATGGVAQGASTLTQQYVKNVFVEQAGSDQKAVLEAQRQTLGRKIQELRYAIELERTLSKDQILTNYLNITFFGEQAYGIEAAATRYFSVSAKDLSLPQAALLAGLVQSPSMYDPVTHPQAAKQRRDTVLNQMAKYGSISAAQAQQAISTPVRLKVSAPRQGCITAHLGEGFFCDYVHRIVLSDPAFGRTAAERRALWSRGGLQIRTTLSPKAQKALQDSVTSHAYTTDDAAAVMSLVQPGTGKIVAMGQSRDYGLGAHQTEINLNVGTRMGGGLGFPTGSTFKPIVAAAALEKGMSPDQKYPAPYSMPWPAMSDCAGNTYPENGEVHNDSPSLTGPFGMPDAMAQSVNTYFAQLEADTGLCDVAKMANALGITAQAGGTKLQVVPSLTLGSNDLTPLEMANVYATFANHGTYCTPVALTSVTKPDGGSVPVPGADCHPVMSAETADTITTMLLGVVQDGTGKPAGLTDRDSAGKTGTTDESKQVWFAGYTPELAGAAVVSDTRAPRDLDGQSIGGETVGQAFGGTLAGPVWRDSIEGALEGQPAGTLTTTTLPGSGG
>CP032698.1|AYG79271.1|1531291_1531939_+|Transcriptional-regulatory-protein-DegU
MRIVVAEDLYLLRDGMVRLIEAYGHEVVATATTGPETLAALLKWRPDVAVVDVRMPPTQSDEGLRAALAARREVPGLPVLILSQHVEQLYARELLADGAGGIGYFLKESVFDADQFMDALERVAAGGTAMDPAVIAKLFSSGSSNRLLEALTEREHAVLSLMAEGLSNAAIGQRLFLSESAISKYTTSMFGKLGISDDDTGNRRVLAVLTYLNNP
>CP032698.1|AYG79270.1|1530047_1531307_+|Sensor-histidine-kinase-DesK
MRGMRSWVTSVGVGLVRAFAVVAVALLVPVVWAAAVLLGIAWGPSNPWSWLAPAVLVGVGTLGLSRPVCRTVRFLVARWSSTVIASGYRRPGPVTQLTTGYWWNGFGYERTDRDAVLDQKMRLRWRDPANWRDLRFVVILPVTAGLVAAVPPAGVAAAVLGFGGSGFLANGVGVLGVAVALGSAPYAWRSLEPVAVRFLRPSAAMTLADRVDELTAQRADTTIAQAAEIRRIERDLHDGAQARLVALGMSLATAEKLMERDPERAKALMREARTGAATSLTELRDLVQGINPPVLNERGLVDAVRAFALDSPLEVRVEADVELRLEPPVESALYFGVVELVTNAVKHAQASRARISLTRTGPDLVVVVEDDGRGGADPRSGGGLDGLRRRLAVFDGTLEITSPAGGPTRARMMVPCASW
>CP032698.1|AYG79269.1|1529424_1529856_-|hypothetical-protein
MDTTHRTAPSPLRDDNEQAFTTTKLIVKAYGALSAGVLITVVVRALTGHTVTSFMWGRSIGVLASAAVTYWLTVLAARGKRWAYVRVRIVSVVVPVAVVAVDVIPGTLPVWFIALHTICALTLAATAFVVNGSGLRAAFPKTR
>CP032698.1|AYG79268.1|1527085_1529143_-|hypothetical-protein
MSHLRAPAARPDRREGGRHGRTTTRPQSPSDATRSAPAGRAPAPPGPRPSPESRIRPQLLRAAVLPATVAVLCGAAAVAFTLHSTGRHPSVGLWATLAGLAGLAIAALVAAGIGADRTAKTVLGRANALRRGSARSAADLRTVVEALRRGEGPPARGTPAQLPQGADEFELLAHELTRSHDAAVVAVVQASQLSSSVGNEQKVEVFVNLARRLQSLVHREIQLLDELENEVEDPELLKGLFHVDHLATRIRRHAENLAVLGGAISRRQWSHPVTMTEVLRSSIAEVEQYPRVKLVPPIDGTLRGHAVADVIHLLAELVENATVFSAPHTQVLLRAQFVTAGLAVEVEDRGLGMPVTEQNKMNALLSDPDQVNVAHLLQDGRIGLFVVSALARRHGIAVRLQTNIYGGVQAVLVLPQGLLGAEPDGLNNQSHPQPEAAHDAVRDGTGRLPETGAAPQLTGASEPAPAPASAPAIAPLHPEPAPPAPVHQEPVRLAPPLPEPALPEPVYQEAAYQERAYQEPVRQKAPRPEPEPQARPGSDPLPPPRTHVAEPTTAGRGNGPLPVRAAHEERPNPASASPGVQHGTSYEPAEPRLITAPRVQNGAVRGTMGRPDLPRRRSQEHLVPQLRDAPEPRRNDEHALHDPGLMAAFQRGIGLAEAQQSHPAPSTHPSPQALQSETDAEHSKE
>CP032698.1|AYG79267.1|1526643_1527078_-|Serine-protease-inhibitor
MASDAPTGHVSDLDWLLSGLVQRVPYTRNAVLLSSDGLVKSVHGLDTDSADHMAALASGLYSLGRSAGARFGDGGEVRQVVVELDSTLLFVSTAGSGTCLAVLAGREADAAVLGYEMAMLVKSVRPYLVTPARQGAGTSSGLRS
>CP032698.1|AYG79266.1|1526269_1526641_-|hypothetical-protein
MAAPQDGPWLDDAAGRLIRPYTVSNGRTRPTATLDLLSQVMATGTLPQTLLGPEHSQALGLCKGPTSVAEISAHLRLPAVVTKVVLSDLVDCGAVTARAPRFQHTPTDRSLLEAVLDGLRRRL
>CP032698.1|AYG79265.1|1525671_1526292_-|hypothetical-protein
MAYDDGFDALPDDGTAVDLFPTALKILVAGGFGVGKTTFVGAVSEIEPLSTEELLTTVSVAHDSLEGIESKTTTTVAMDFGRITLDDQHVLYLFGTPGQERFWFMWDELSEGALGAVILADTRRLDECFSAVDFFERRGIGFLVAVNEFDGSYRYDPEEVRAAIDLKPEVPVVLCDARIGSSGIRTLVTLVQHLLATIPAATSHGA
>CP032698.1|AYG79264.1|1525099_1525669_-|hypothetical-protein
MTYDPTGHLLLTPVDREAPVRVQRLRQLGMGERPDPAFDEFASKLAAVTGAPFSMVNFIDENQQFFAGLHTPNGTHNGSDLGAAAAAGGVSRIMARDHGYCPHVVVRRKALVLEDVCDYPRFAGNPVVDEIGIRSYLGAPLIDRTGIALGTICVVDTEPRPWGRAGLETIKTMAAELVEQIHRREDGHF
>CP032698.1|AYG79274.1|1535306_1535789_-|hypothetical-protein
MEQHGARVVADLGRELAAASSQTGGALWRLAESGRGLDANLLRLPPGRAIDEHTDLVLDVLLVVLEGSGELRTESGSQDLRPVSALWLPKGSRRALVAGADGMGYLSVHQRRPGLTIGTPPRPEAGEEAGLLARVCPECGRLAPERAARFCWSCGSALEA
>CP032698.1|AYG79275.1|1535922_1536441_-|hypothetical-protein
MTPTLRTERLLLDPYTPDDEEDFVALFQDRRVSRWMGEGPTSEAEDRALFRRVFTQVYARDLFAVWAVRRDGVLIGHAEIKPTEATGGHEIIYALAPAAWGAGLGTELAQAVVAHGFDTLGLTEVHATVAAENTASLTLLARIGFVHVRDIQEDDGSTTRVLTLTRRPPNGP
>CP032698.1|AYG79276.1|1536524_1536968_-|hypothetical-protein
MGTPGKGGDEETVTVRTRPVLVYDGDCAFCTSCASFVERRVRPRCTITPWQFADLDALGVTEQRARYELLWVTPGGVVQGGADAVARLLLSAGRGWAPLGAALTLPPLRWMAHGVYRLVADNRQRLPGGTAACAVRREPGPRPPGGG
>CP032698.1|AYG79277.1|1537014_1538220_-|putative-L-ascorbate-6-phosphate-lactonase-UlaG
MTGAGSLLPLRSRLRELRTDAFGADPAGERMARIRRSPNFADGVFRNPEGETRIRPSGSTVEFAKRFFAKEQRVRRAPTGTIPVHPTTLADLAKPPTTGLRLTWMGHSSVLAEIDGRRVLFDPVWGERCSPFAFAGPKRLHPVPLPLAALGPVDVVVISHDHYDHLDLPTIRALAATDTVFAVPLGVGAHLEHWGVPLDRIHELDWNESAKVDGLTFTATPARHFCGRGLRNQQHTLWASWVVAGPEHRIYHSGDTGYFDGFRDIGAEHGPFDATMIQIGAYSEFWPDIHMTPAEGLRAHLDLQGGAPHGVIMPIHWGTFNLAPHPWAEPGEWTKDAAQEANQAAAFPRPGEPFEPAAALPGDPWWQALSVPLAHPWRRPRPAGIRPSATPAADLDLAGDR
>CP032698.1|AYG79278.1|1538493_1539054_+|Ribosomal-protein-serine-acetyltransferase
MARQQQPSFVLPGGRELRPWRESDADVLVASALDPDIVRWNRVEQLSLEAARAKIAHWGQRWTEEQAAIWAISRRADDRAVGLIGLADFDLRGGSAEILYWLLPAGRGGGAALDATLRVSRWALDELGLHRIRITHSVSNPASCRVARRAGFALEGTMRSALLHADGWHDEHLHARVAGDPWPAGG
>CP032698.1|AYG79279.1|1539885_1540677_+|Peptidoglycan-N-acetylglucosamine-deacetylase
MLKNTARSRRPRAAATASLAAAAVLGLALAGCGQDSTSPQEARGRADTRVQAKAARTAGTVDCARAKCIALTFDAGPGPHTPQLLDILKEKKVHATFFLLGSKHVDTYPDIVRRAAAEGHEIANHTWTHRRLDQLKPDEIRSELGRTQRAVEALTGRAPTLMRPPQGRTNDEVTAVSKELGLSQVLWSATAKDYATTDSALIHKRILDQASRDGIILLHDIYDGTVPAVPGIIDELTERGYTFVTVPQLLAPGTPQPGTLYRP
>CP032698.1|AYG79280.1|1540717_1541761_+|hypothetical-protein
MRAAPGRVEGMRVVLLGGTEFVGRAVTEAALARGHEVTVFHRGRHEPPAGVLSLHGDRTADGGLAALTDGGWDVVVDTWSGAPAVVRDAARLLAGRVGRYVYVSSRSVYAHPTPPDAGEDAPLVAGSPDDGDAADYPRAKRGGELAVVRELGEDRALLVRAGLILGPGENIGRLPWWLARAARGGDMLAPGPRDAGIQYIDCRDLAEWTLDAAEAGRGGAYDLVSPVGHATMGALLDACVHVTGGRAVPRWTDPEPILAAGIEPWLHLPVWIPPGEQHDTMHGSTVAKALAAGLRCRPVLETVADTWAWLGSIGGSAPQRPDRPRVGLDPEVERKVLAGRPREEASS
>CP032698.1|AYG79281.1|1541811_1542603_-|hypothetical-protein
MADDSRSFSSGTFGSYTAIGDSFTEGVGDPGPDGTFVGWADRFAVLLGDQRPEGTFRYANLAVRGRLLDQIVEEQVPRAKELAPDLVSFCAGGNDIIRPGTDPDEVAERFERALADLKPAVGTVMVTTGFDTRGVTLLRHLRGKIATYNGHVRAIADRYGCPVLDLWSLKSIQDRRAWDNDRLHLSPEGHTRVALRAAQVLGLDVPADPDQPWPPLPPRNSLEVRRDDINWAREYLVPWIGRRLRGESSGDEVSPKRPDLLPL
>CP032698.1|AYG79282.1|1542817_1544011_+|hypothetical-protein
MSNDTVNSAPASPATTEEALPLSDAALDALAERVAAGATIVGVGESTRFSRETFGVRDQLLRRLVRDHGFRALAVQDSAGVGATLDAYVGGGADSAAAALDHAWRPQRTAEMAAALEWIRAFNRAHPHDPVRVFGVKPAQAGREDYDAVLEHVRARAPQLLARTASHLDPIRTAHDLDEHVQRARGTHPGRPFAEHARDALALLRSLPEGEGREAALAHMRLIVDFHEHSVAGRGDYAGEATAWSDVVAGFQRRSGTRVVYWDGIAHTAAAGTVLGMAPGQDARATVGSVLRARYGDRYVSVAIGFHHGDLGVTVVPEPLAGSLDARLGEVDAAAHWLDLRRDDVRRHWQGPAKARVISGVYDPRDDAAGYLTVDSVAEAFDVLVHIRRASAVRWLA
>CP032698.1|AYG79283.1|1544088_1546188_-|Bifunctional-alpha-galactosidase/sucrose-kinase-AgaSK
MIETGDNGRLWLLTGRSSSYALHLTDDDELLHLHWGPRITVADATALAREPLPPPWPFESRLDGREEYPVEGGPRFVRPALSVRAGRARGTACDFTGAEVAPDELRLCFTDPVNGLAITLHYRMRDEFDVLERWTTAAHQGADGEVELLRADAATWTLPERDGWRLSHLHGRWAAESRLVRCDLTPGETVLGSRRGHTGHQHLPWVALDADAQATEESGEVYGCALAWSGSWRIAVQRLPDGRVQINGGAGYDDAGLVLLAPGESYTSPVFAGLWSGEGFGGASRQWHAWQLAEVIPGAEQPRPVLYNSWEATLFDISEDQQRALAHRAAEMGVELFVVDDGWFGARTHDGAGLGDWTPNSQRFPAGLKPLADEVHALGMRFGIWVEPEMVNPDSDLYRAHPDWVQFQPGRPRTEFRNQLVLNLARQDVREYVGEQLDALLSSAPIDYVKWDFNRCFTDAGWPGEAYPQKLWTEHVHAFYALLDRLRAAHPHVAFESCSGGGGRVDLGVLSRTDQVWTSDNTDPLDRLAIQHGFSQLHPARVMAAWVTDSPNTQLNGRVSSLRFRFVSAMAGVLGVGGDLSRWSPAERAEARDWVALYKEIRPVVQLGAQYRLRAPEGGLSAVQYTYGCDTVVLAWLQAQHYGEPPPAVRLRGLDPAASYARVDTGAVHSGAVLLHRGLVTGLRGDLDAAVFRLRRVEG

Crispr_ID: CP032698_4

• CRISPR_ID: CP032698_4
• CRISPR_location: 1805399-1805480
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_4

Consensus_repeat	Method
GCGCAGTTCCTCGCGCCCCTGGGG	CRISPRCasFinder

spacers of CP032698_4

>4.1|1805423|34|CP032698|CRISPRCasFinder
TCCCTGGTTACGTGCGGGGTCGTGGCCGCTTCTC

CRISPR arrays and Neighbor proteins around CP032698_4

CRISPR arrays

The CRISPR arrays of CP032698_4

>merge|CP032698|4|1805399-1805480|CRISPRCasFinder
GCGCAGTTCCTCGCGCCCCTGGGGTCCCTGGTTACGTGCGGGGTCGTGGCCGCTTCTCGCGCAGTTCCTCGCGCCCCTGGCG

>CP032698|4|4|1805399-1805480|CRISPRCasFinder
GCGCAGTTCCTCGCGCCCCTGGGG	TCCCTGGTTACGTGCGGGGTCGTGGCCGCTTCTC
GCGCAGTTCCTCGCGCCCCTGGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG79506.1|1804393_1805242_+|hypothetical-protein	unknown	unknown	gnl|CDD|224104
CP032698.1|AYG79499.1|1796223_1797048_+|Putative-mycofactocin-biosynthesis-transcriptional-regulator-MftR	unknown	unknown	gnl|CDD|188483
CP032698.1|AYG79509.1|1809483_1811199_+|Glycine-betaine-transporter-BetP	unknown	unknown	gnl|CDD|376718
CP032698.1|AYG79508.1|1808186_1809341_-|Glycerate-2-kinase	unknown	unknown	gnl|CDD|376844
CP032698.1|AYG79502.1|1800826_1801801_+|L-malyl-CoA/beta-methylmalyl-CoA-lyase	unknown	unknown	gnl|CDD|225184
CP032698.1|AYG79500.1|1797451_1798789_+|Crotonyl-CoA-reductase	unknown	unknown	gnl|CDD|188164
CP032698.1|AYG79505.1|1803744_1804401_+|Phosphatidylserine-decarboxylase-proenzyme	unknown	unknown	gnl|CDD|235400
CP032698.1|AYG79510.1|1811259_1811772_+|hypothetical-protein	unknown	unknown	gnl|CDD|239217
CP032698.1|AYG79501.1|1798802_1800830_+|Methylmalonyl-CoA-mutase	unknown	unknown	gnl|CDD|239653
CP032698.1|AYG79515.1|1816840_1817368_-|O-acetyl-ADP-ribose-deacetylase	unknown	unknown	gnl|CDD|234759
CP032698.1|AYG79511.1|1811819_1813028_-|hypothetical-protein	unknown	unknown	gnl|CDD|376564
CP032698.1|AYG79516.1|1817364_1818789_-|Putative-thiazole-biosynthetic-enzyme	unknown	unknown	gnl|CDD|224154
CP032698.1|AYG79503.1|1801806_1802343_+|Mesaconyl-CoA-hydratase	unknown	unknown	gnl|CDD|239535
CP032698.1|AYG79507.1|1805990_1807514_-|Antiseptic-resistance-protein	unknown	unknown	gnl|CDD|184957
CP032698.1|AYG79498.1|1794368_1796150_+|3-hydroxybutyryl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|181133
CP032698.1|AYG79504.1|1802345_1803560_+|(2S)-methylsuccinyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
CP032698.1|AYG79514.1|1814652_1816146_-|putative-bifunctional-transcriptional-activator/DNA-repair-enzyme-AlkA	unknown	unknown	gnl|CDD|225080
CP032698.1|AYG79512.1|1813409_1814132_+|NAD-dependent-protein-deacetylase	unknown	unknown	gnl|CDD|238701
CP032698.1|AYG79497.1|1793349_1793976_-|hypothetical-protein	unknown	unknown	gnl|CDD|224331
CP032698.1|AYG79513.1|1814142_1814640_-|Methylated-DNA--protein-cysteine-methyltransferase	unknown	unknown	gnl|CDD|234860

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG79506.1|1804393_1805242_+|hypothetical-protein	gnl|CDD|224104	COG1183, PssA, Phosphatidylserine synthase [Lipid metabolism].	1.51211e-33
CP032698.1|AYG79499.1|1796223_1797048_+|Putative-mycofactocin-biosynthesis-transcriptional-regulator-MftR	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	5.96624e-18
CP032698.1|AYG79509.1|1809483_1811199_+|Glycine-betaine-transporter-BetP	gnl|CDD|376718	pfam02028, BCCT, BCCT, betaine/carnitine/choline family transporter.	0
CP032698.1|AYG79508.1|1808186_1809341_-|Glycerate-2-kinase	gnl|CDD|376844	pfam02595, Gly_kinase, Glycerate kinase family. This is family of Glycerate kinases.	1.04636e-164
CP032698.1|AYG79502.1|1800826_1801801_+|L-malyl-CoA/beta-methylmalyl-CoA-lyase	gnl|CDD|225184	COG2301, CitE, Citrate lyase beta subunit [Carbohydrate transport and metabolism].	4.26053e-77
CP032698.1|AYG79500.1|1797451_1798789_+|Crotonyl-CoA-reductase	gnl|CDD|188164	TIGR01751, crotonyl_CoA_reductase, crotonyl-CoA carboxylase/reductase. The enzyme represented by this model can convert crotonyl-CoA to butyryl-CoA (crotonyl-CoA reductase activity), but more importantly, in the presence of CO2, generates (2S)-ethylmalonyl-CoA. In serine cycle methylotrophic bacteria this enzyme is involved in the process of acetyl-CoA to glyoxylate. In other bacteria the enzyme is used to produce extender units for incorporation into polyketides such as tylosin from Streptomyces fradiae and coronatine from Pseudomonas syringae.	0
CP032698.1|AYG79505.1|1803744_1804401_+|Phosphatidylserine-decarboxylase-proenzyme	gnl|CDD|235400	PRK05305, PRK05305, phosphatidylserine decarboxylase family protein.	4.62809e-91
CP032698.1|AYG79510.1|1811259_1811772_+|hypothetical-protein	gnl|CDD|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	1.60488e-17
CP032698.1|AYG79501.1|1798802_1800830_+|Methylmalonyl-CoA-mutase	gnl|CDD|239653	cd03681, MM_CoA_mutase_MeaA, Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, MeaA-like subfamily; contains various methylmalonyl coenzyme A (CoA) mutase (MCM)-like proteins similar to the Streptomyces cinnamonensis MeaA, Methylobacterium extorquens MeaA and Streptomyces collinus B12-dependent mutase. Members of this subfamily contain an N-terminal MCM domain and a C-terminal coenzyme B12 binding domain. S. cinnamonensis MeaA is a putative B12-dependent mutase which provides methylmalonyl-CoA precursors for the biosynthesis of the monensin polyketide via an unknown pathway. S. collinus B12-dependent mutase may be involved in a pathway for acetate assimilation.	0
CP032698.1|AYG79515.1|1816840_1817368_-|O-acetyl-ADP-ribose-deacetylase	gnl|CDD|234759	PRK00431, PRK00431, ADP-ribose-binding protein.	5.17727e-81
CP032698.1|AYG79511.1|1811819_1813028_-|hypothetical-protein	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.64843e-57
CP032698.1|AYG79516.1|1817364_1818789_-|Putative-thiazole-biosynthetic-enzyme	gnl|CDD|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	4.52418e-84
CP032698.1|AYG79503.1|1801806_1802343_+|Mesaconyl-CoA-hydratase	gnl|CDD|239535	cd03451, FkbR2, FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown.	1.13854e-70
CP032698.1|AYG79507.1|1805990_1807514_-|Antiseptic-resistance-protein	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	4.81227e-86
CP032698.1|AYG79498.1|1794368_1796150_+|3-hydroxybutyryl-CoA-dehydrogenase	gnl|CDD|181133	PRK07819, PRK07819, 3-hydroxybutyryl-CoA dehydrogenase; Validated.	8.36255e-106
CP032698.1|AYG79504.1|1802345_1803560_+|(2S)-methylsuccinyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	6.11941e-134
CP032698.1|AYG79514.1|1814652_1816146_-|putative-bifunctional-transcriptional-activator/DNA-repair-enzyme-AlkA	gnl|CDD|225080	COG2169, Ada, Adenosine deaminase [Nucleotide transport and metabolism].	2.20998e-56
CP032698.1|AYG79512.1|1813409_1814132_+|NAD-dependent-protein-deacetylase	gnl|CDD|238701	cd01410, SIRT7, SIRT7: Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span.	1.24051e-92
CP032698.1|AYG79497.1|1793349_1793976_-|hypothetical-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	0.000214741
CP032698.1|AYG79513.1|1814142_1814640_-|Methylated-DNA--protein-cysteine-methyltransferase	gnl|CDD|234860	PRK00901, PRK00901, methylated-DNA--protein-cysteine methyltransferase; Provisional.	7.16361e-61

Protein sequences

>CP032698.1|AYG79506.1|1804393_1805242_+|hypothetical-protein
MIDPETQAGWVPEAESEDDVEEMPLSLRLSIADTLTLGNATCGFMAVYFTTTGILIPHLSGSQETGMARHSAATAVILMLLAAIFDLCDGLVARKLRSSPMGAELDNLSDLISFGLAPAYFVLVYGMVADDAHQRVAAVAAITVLLAVVLRLARFSCVTMKDGMFQGMPSPFGALTVVSIVLLELPFVPTLLAVIGVAWLMVSRVEYPKPRGVLAVAMLSWIIGAMGLLAAWAFDAPGGQMLLQTGCALQIVLAATIPLFATARRVNTFRDNRREARAGQLP
>CP032698.1|AYG79505.1|1803744_1804401_+|Phosphatidylserine-decarboxylase-proenzyme
MPHSQTSAPRDGFLKGRLARGASPWLLPTVATAALSLARSRRSKSAAIVAVPTTALAAGMLWFFRDPEREITQGRVISPADGVVQSIMPWKDGRTRVAIFMSPLNVHVNRAPLAGTVTSVEHIPGGFVPAFNKESENNERVVWHFDTELGDIEMVQIAGAVARRIVPYIPQGTKVEQGERIGLIRFGSRVDIYLPEGVEVAVEVGQATTAGVTRIDRD
>CP032698.1|AYG79504.1|1802345_1803560_+|(2S)-methylsuccinyl-CoA-dehydrogenase
MARLAQTAGLTDVQQEILSTVRDFVDKEIIPVATQLEHKDEYPTQIVEGLKELGLFGLMIPEEYGGLGESLLTYALCVEEIARGWMSVSGIINTHFIVAYMLKQHGTQEQKDTFLPRMALGEVRGAFSMSEPALGSDVSAITSKGVRDGEEYVLNGQKMWLTNGGTSSLVAVLCRSDEGHSPEEVAARPHKSMTTFLVEKEPGFGEVRPGLTIPGKIDKMGYKGVDTTELVMDGLRIPTNRVLGGVTGRGFYQMMDGVEVGRVNVAARGCGVAQRAFELGVSYAQQRHTFGKPIAQHQAIQFKLAEMATKVEAAHAMMVNAARKKDSGERNDLEAGMAKYLASEYCKEVVEDAFRIHGGYGFSKEYEIERLYREAPMLLIGEGTAEIQKMIIGRRLLEEYRFQG
>CP032698.1|AYG79503.1|1801806_1802343_+|Mesaconyl-CoA-hydratase
MQFGRTYEEFEVGAVYKHWPGKTVTEYDDHLFCLLTMNHHPLHMDVNYAENTTDFGKNVVVGNYIYSLLLGMSVPDVSGKAIANLEIESLRHVAPTFHGDTIYGETTVLDKTPSKSKNDRGIVYVETKGYKQDGTLVCVFRRKVMVPTETYIKERGGEQPGRPVLVEPAKKPAQKSEK
>CP032698.1|AYG79502.1|1800826_1801801_+|L-malyl-CoA/beta-methylmalyl-CoA-lyase
MSTPVSPVNRLRPRRSCLAVPGSNPRFLEKAQGLPADQVFLDLEDACAPLAKPEARHTIVKFLNEGDWTGKTRVVRVNDWTTEWTYRDVVTVVEGAGQNLDCIMLPKVQSADQVVALDLLLTQIEKTMGFEVGKIGIEAQIENARGLNNVNAIAEASPRTETIIFGPADFMASINMKSLVVGEQPPGYGADAYHYILMKILMAARANDLQAIDGPYLQIRNVDGYREVAKRAAALGFDGKWVLHPGQVEASNEIFSPSQEDFDHAELILDAYDYCTSEAGGKKGSAMLGDEMIDEASRKMALVISGKGRAAGMQRTSKFEIPEA
>CP032698.1|AYG79501.1|1798802_1800830_+|Methylmalonyl-CoA-mutase
MTERQKDRPWLMRTYAGHSTAEASNELYRNNLAKGQTGLSVAFDLPTQTGYDPDHILARGEVGRVGVPVSHLGDMRRLFQDIPLEQMNTSMTINATAMWLLAMYQVVAEEQGADITKLQGTTQNDIVKEYLSRGTHVFPPGPSLRLTTDMICYTVNNIPKWNPINICSYHLQEAGATPVQEIAYAMSTAIAVLDSVFASGQIPDDRRGDVVARISFFVNAGVRFIEEMCKMRAFGRIWDKITRERYGIEDAKQRRFRYGVQVNSLGLTEAQPENNVQRIVLEMLAVTLSKDARARAVQLPAWNEALGLPRPWDQQWSLRIQQVLAHESDLLEYEDIFEGSHVIEAKVEALVEECLAEIGRIEEMGGALAAVESGYLKSQLVSSHAERRARIEAGEEKIVGVNCYETTEPSPLTADLDGAIMTVDPAVEARVVAALKNWRDTRYQPPFNHPRPCKALEKLKQAAEGTGNLMEATLECVRSGVTTGEWSQALREVFGEFRAPTGVSSAPVAVTAEEGTPLAAVREKVARTAEELGSGRLRLLVGKPGLDGHSNGAEQIAVRARDAGFEVVYQGIRLTPEQIVSAALAEDVHCVGLSILSGSHAELVPDVLVRLREAGAADIPVIAGGIIPPADAADLRAAGVAAVFTPKDFGITEIIGRIVDEIRKANKLDPLEVPA
>CP032698.1|AYG79500.1|1797451_1798789_+|Crotonyl-CoA-reductase
MKEILDAIQSPESTSADFAALPLPESYRAITVHKDETEMFDGLTTRDKDPRKSIHLDEVPIPELGPGEALVAVMASSVNYNSVWTSIFEPVSTFSFLERYGRLSELTKRHDLPYHIIGSDLAGVVLRTGPGVNAWNPGDEVVAHCLSVELESSDGHNDTMLDPEQRIWGFETNFGGLAEIALVKSNQLMPKPKHLSWEEAAAPGLVNSTAYRQLVSRNGAGMKQGDNVLIWGASGGLGSYATQFALAGGANPICVVSSPEKADICRAMGAEAVIDRNAEGYKFWKDERTQDPKEWKRFGKRIREFTGGEDIDIVFEHPGRETFGASVYVTRKGGTITTCASTSGYMHEYDNRYLWMSLKRIIGSHFANYREAWEANRLIAKGKIHPTLSKVYSLEDTGQAAYDVHRNLHQGKVGVLALSPREGLGVSDPELREKHLDAINRFRNV
>CP032698.1|AYG79499.1|1796223_1797048_+|Putative-mycofactocin-biosynthesis-transcriptional-regulator-MftR
MQYVRSMPQPTRSSRTNAVPDAPESAAGSRAAAQRLKMRRELAAAAMDLFSAKGYEATTVDEIAAQAGVARRTFFRHFRSKEEAIFPDHDDTLVRAEAVLNAAPPHEHPLDTVCRGIKEVMKMYAGSPSVSVARYKLTREVPTLREAEIASVARYERLFTRYLLGHFDEHDHQPGNDDPLLAEVAASAVVTAHNHVLRRWLRAGGQGDVEAQLDHAFAIVRETFGSGIGAGRTAAPQPAAASVSTSDEVLVAVARTDAPLDEIMQSIKQALKSR
>CP032698.1|AYG79498.1|1794368_1796150_+|3-hydroxybutyryl-CoA-dehydrogenase
MDVPLNTVAVVGLGTMGTGIAEVLARAGREVIGIDISERAGRQAVASLEASTARSVARERITPQERGDILARFRTFTDLQAAAEAELVIEVVPESYELKHQVFQALDAIVAPTAILATGTNALSVTRLAADSAHPERVIGLHFFNPAPAMKLVEIVSSVLTAPPAVDAVTALALDLGKEPVAVGDRPGFVADGLLFGYLNQAAAMYESKYASREDIDAAMKLGCGLPMGPLELLDLIGIDTARTVLEAMYASSQDRLHAPAPILGQLAEAGLTGRKRGRGFYTYEGEGSAVTVADAQTPDTIAGAGGGREVRSVGVAGSGTMASGIAEVFAKAGYHVVLAARSLEKAETAKSRIATSLSRSVDKGRLTAEAREETLNRITAAGALEAFAEVDLAVEAVAEDLEVKQQLFASLDKICKPGAVLATTTSSLPVVACARATSRPQDVIGMHFFNPAPAMKLVEVVRTVLTSDEVHATVREVTAKIRKHPVDCGDRAGFIVNALLFPYLNNAIKMVQEHYATLDDIDAAMKLGGGYPMGPFELLDVVGLDVSLAIEKVLHAEFRDPGLAPAPLLEHLVAAGCLGRKTGRGFREYARR
>CP032698.1|AYG79497.1|1793349_1793976_-|hypothetical-protein
MHRRGEAKVHRILDMDEELRSLLDRVRGETGGSPAYERLIATVDHGELAAVLVEPERPLWAREIAAFRLGVAGDRRAFEALILLLNHRDPERCVTAAYALARLGDPRTARAAAALATNELRTAYALHPVRLLTALRAPESVPALITTLRPLLSPHSPYWRVAQACIEGLGELGDLRAVEVLTEALAQPRLARSAAWALRRIRAGRGRG
>CP032698.1|AYG79507.1|1805990_1807514_-|Antiseptic-resistance-protein
MTSPPLDPRRWVVLAILSGSLLLIAMDTTILNVAFPSLVSDLQPSSVQQLWIIDVYALALSGLLVTAGALGDRWGRKRLLLAGFTIFASASLMAVFATEAWQVIAARALLGVGGAAIMPSTLSILRDVFTDARERALAYAVWAAVFGGGMALGPVVGGLLVERNGWQSAFLINVPVALVIIALGAWILPESRQPREGRWDWWGVGQSVVGMLALAGGIKQLGKGGPADPVAWMLLVVAAVALTVFVRRQLRLPQPLFHVRLFTNRSFSIAAASIFLGMIALGSALFLVTQWFQYAQGYSPLEAGVRLLPAPLGLVVTSLVTPVLMHRLPIRHVIGGGLLLMTAGLALPWLFQQSGPLGYPGVAVALGVLGCGVGVATTAASVTLMASAPKEHVSGAAAVEETCYELGAAMGVAILGSVAGALYRGHLPELAVDGAAAASVRDSVGEAAHVASAVGGPAGAELLAKASSAFTFGMTPTFMLAAVLPLAAAVLAWSKIPRDLRPTETSH
>CP032698.1|AYG79508.1|1808186_1809341_-|Glycerate-2-kinase
MTDGAVLETARVLVAADKFKGSLTAVEVAERVTAGLRRVVPDLRVETLPVADGGDGTVAAAVAAGFERREARVTGPLGTPVTAAYAVRDGVAVVEMAEASGLQHLPEGVFAALTATTYGSGELLLAALDAGARTIVFGVGGSATTDGGAGMLAALGARFLDGAGEPVGPGGGALADLATADFSGLDARFKDVELVLASDVDNPLTGPKGAPAIYGPQKGASPEDVATLDAALAHYAKVLEGVLGAKAAEAALAPGAGAAGGIGYGALVALDAVFRPGIEVMLDVLGFAPALAGATLVITGEGSLDEQTLHGKAPAGVAAAARAAGIEVVAVCGRLLLQPGQLGEAGIRRAYALTELEPDPARCMANAGPLLEQAAQNIASDFLL
>CP032698.1|AYG79509.1|1809483_1811199_+|Glycine-betaine-transporter-BetP
MTSDSIDHSGSGAPPDDVRPDLDPAPDRTLITVGVLAVVAVVAWAAWGKSSFDSASSTALAWVLDNFAWLFVVAADTFLVLCLVLAVSRYGRIRLGADDSEPEFTNLAWIAMMFSAGMGIGLMFYGVGEPLTHFLSPPPATGAQPGSGDAARTALEYSFFHWTLTPWAIYGIAGLALAYAGFRKQRGNRLSSAFVPLIGARRADGRVGRCIDLLAVFATVFGTATSLGLGALQVAEGLDITSGVHNSRTTQLVIIAALSAAFVLSAFSGLHKGVKWLSTINLVLAAVLMVFVFLLGPTVYVLDTIPASIGGYLHDLLPMASRTGAFTDRAWLGAWTVFYWAWWLSWAPFVGTFIARISRGRTIREFLIGVLLVPSGATVIWFCVMGGTAIRLASTGAADLAGAVRDGAEASLFATLDALPIGTVTSYIAMALVMTYFITSADSASLVMGSLTSRGSLHPPTWLVVMWGVLMAAVAAVLLVAGGLKSLQTATILVALPFVVVMLGLCWSLVKELREDPGAGPSRHGALHGLRDAVRTMVGDAITEQGAARHHRLRRAAKSRTGDESSGTPQP
>CP032698.1|AYG79510.1|1811259_1811772_+|hypothetical-protein
MTTDHSPAPDNAYTAYIAGLPRVLAGAAALFRDAGGKVLLVEPNYREGWALPGGTVESDTAETPRRAARRETLEEIGLDVELGRLLAVDWVHGEARPPIVAYVYDGGVLDDSLLKSIRLQEEELLSWRLVPREELPTHLPGALGHRVMAALDVLAQGQGTAELENGHRVG
>CP032698.1|AYG79511.1|1811819_1813028_-|hypothetical-protein
MFDTEDVGVFLGLDVGKTAHHGHGLTPAGKKVFDKPMPNSEPKLRAVFDKLTAKFGTVLVIVDQPASIGALPLTVARDAGCKVAYLPGLAMRRIADLYPGEAKTDAKDAAVIADAARTMPHTLRSLELTDEITAELTVLTGFDQDLAAEATRTSNRIRGLLTQFHPSLERVLGPRLDHPAVTWLLERYGSPAALRKAGRRRLVELIRPKAPRMATRLVDDVFDALDEQTVVVPGTGTLDTVVPSLARSLAAVHEQRRALEAQIKALLEDHPLSKVLTSMPGVAVRTAAVLLVTVGDGTSFPTAAHLASYAGLAPTTKSSGTSIHGEHAPRGGNRQLKRAMFLSAFAALHDPASRTYYDKCRARGKTHTQALLRLARHRISVLFAMLRDGTFYEPRVPEAAVA
>CP032698.1|AYG79512.1|1813409_1814132_+|NAD-dependent-protein-deacetylase
MGKPLVAILSGAGISTDSGIPDYRGPNGLWRRDPEAEKLVTYSSYMADPEIRRRSWLMRRDSPALKAEPNAAHRAVAELERSGVPVRVITQNVDGLHQRAGLSERKVLELHGTARAVTCTRCHARSSMAEALARVTAGEADPPCTVCGGILKSATVMFGERLDPEVLSQAMAIAKACHLFIAVGTTLQVQPAASLAGIAADGGARLIIVNADPTPYDPLADEVIREPIGTALPRLLRALP
>CP032698.1|AYG79513.1|1814142_1814640_-|Methylated-DNA--protein-cysteine-methyltransferase
MRITHTVIDSPYGPLTLVAADGVLSRLYMEGQRHRPPQETFGERDDDGPFPEVARQLEAYFTGQLTAFDVDLNMLGTPFQQRVWHQLQQIPYGETRSYGELAEALGNPNASRAVGLANGKNPVGIIVPCHRVIGANGSLTGYGGGLDRKQRLLAFERGRTADVLF
>CP032698.1|AYG79514.1|1814652_1816146_-|putative-bifunctional-transcriptional-activator/DNA-repair-enzyme-AlkA
MAPVAPAPMHTDTERCVRAVQSKDARFDGWFFTAVLTTRIYCRPSCPVVPPKVENMTFYPSAAACQQAGFRACKRCRPDTTPGSPEWNARADSVARAMRLIRDGVVDREGVPGLAARLGYSARQIERQLLAELGAGPLALARAQRAQTARLLIETTPLPMAEVAFAAGFSSIRTFNDTVREVFALAPSELRTRAARGVARQTPGAITLRLPFRAPLTPDNLFGHLAATGVPGVEEWRDGSFRRTLSLPYGHGIAELTPQPEHIGCVLRLTDLRDLTIAISRCRWMLDLDADPVAVDDRLRADPLLAPLVDKAPGRRVPRTVDAEEFAVRAVLGQQVSTAAARTHAARLVVAHGQAIDDPTGGLTHLFPTPDRLAELDPQNLALPRSRRTTLTTLVAALADGTLRLGLDSDWDRARAQLMELPGFGPWTVEAIAMRALGDPDAFLPTDLGMRRAAQNLGLPSTPAALTARAAAWRPWRAYAVQYLWATEAHAINHLPA
>CP032698.1|AYG79515.1|1816840_1817368_-|O-acetyl-ADP-ribose-deacetylase
MTARPVDIVLVRGDITEQRVDVIVNAANSSLLGGGGVDGAIHRRGGPAILEECRRLRASHYGKGLATGQAVATSAGRLHAGHVIHTVGPVWSGDEDRSALLTSCYQRSLALARELGAETVAFPAISTGVYGWPLDSGADLAVAAARAYAGPPLREVRFVLFEAAAYEAFDRALRG
>CP032698.1|AYG79516.1|1817364_1818789_-|Putative-thiazole-biosynthetic-enzyme
MPSMLDAVVVGAGPNGLTAAVELARRGLRVEVFEAKDTVGGGARTEELTLPGFRHDPCSAVHPLGIGSPAFRNMPLERYGLEWLHPELPMAHPFDDGTAAVLSRSVAETAASFGARDAGTYRRLMAPLLGTWDVLARDFMSLPLTALPRDPVGLARFGAVGLQPYSWLMRRFRDDRARALMAGLVAHVIAPLNGVATAGVGMLFALAAHENGWPLPRGGSQSISDALTGYLRDLGGVVHTGFEVKRLDDLPPARTYLFDTSPTALARIAGLGRAYDGYKYGAAVFKIDYALDGPVPWTAEEAKAAGTVQIGPSSRDIATALSQASGGTAPRTPFLITAQPSLVDPSRAPEGKQVFWAYGHVPNGWEGDFTDAIERQIERFAPGFRDRVLARAAAGPPQLAARNANYVGGDIACGAARGLQLLLRPKISLFPYATRHPSVFLCSSAAWPGPGVHGMSGHNAAKAVWRALRKADAR

Crispr_ID: CP032698_5

• CRISPR_ID: CP032698_5
• CRISPR_location: 1822179-1822282
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_5

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGGGGG	CRISPRCasFinder

spacers of CP032698_5

>5.1|1822206|50|CP032698|CRISPRCasFinder
CCCGGGCCATCCAACCCTGCGCCTACGGGCGGGTGGGTGGGTAAGGTGCC

CRISPR arrays and Neighbor proteins around CP032698_5

CRISPR arrays

The CRISPR arrays of CP032698_5

>merge|CP032698|5|1822179-1822282|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGGCCCGGGCCATCCAACCCTGCGCCTACGGGCGGGTGGGTGGGTAAGGTGCCCGGGGTCTGGGGCGGAGCCCCAGGGGG

>CP032698|5|5|1822179-1822282|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGG	CCCGGGCCATCCAACCCTGCGCCTACGGGCGGGTGGGTGGGTAAGGTGCC
CGGGGTCTGGGGCGGAGCCCCAGGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG79514.1|1814652_1816146_-|putative-bifunctional-transcriptional-activator/DNA-repair-enzyme-AlkA	unknown	unknown	gnl|CDD|225080
CP032698.1|AYG79517.1|1818869_1819700_+|hypothetical-protein	unknown	unknown	gnl|CDD|376187
CP032698.1|AYG79518.1|1819785_1820613_-|Fructose-1,-6-bisphosphatase/inositol-1-monophosphatase	unknown	unknown	gnl|CDD|238775
CP032698.1|AYG79529.1|1829938_1830643_-|hypothetical-protein	unknown	unknown	gnl|CDD|369321
CP032698.1|AYG79527.1|1828563_1828824_-|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG79510.1|1811259_1811772_+|hypothetical-protein	unknown	unknown	gnl|CDD|239217
CP032698.1|AYG79519.1|1820781_1821837_+|Octanoyltransferase-LipM	unknown	unknown	gnl|CDD|319742
CP032698.1|AYG79515.1|1816840_1817368_-|O-acetyl-ADP-ribose-deacetylase	unknown	unknown	gnl|CDD|234759
CP032698.1|AYG79521.1|1823353_1824757_-|D-hydantoinase	unknown	unknown	gnl|CDD|236240
CP032698.1|AYG79526.1|1828051_1828567_-|RNA-pyrophosphohydrolase	unknown	unknown	gnl|CDD|240041
CP032698.1|AYG79523.1|1826140_1826983_-|N-carbamoyl-D-amino-acid-hydrolase	unknown	unknown	gnl|CDD|143592
CP032698.1|AYG79516.1|1817364_1818789_-|Putative-thiazole-biosynthetic-enzyme	unknown	unknown	gnl|CDD|224154
CP032698.1|AYG79522.1|1824860_1826144_-|Acetylornithine-aminotransferase	unknown	unknown	gnl|CDD|99735
CP032698.1|AYG79524.1|1827157_1827658_-|putative-phosphatase	unknown	unknown	gnl|CDD|319796
CP032698.1|AYG79511.1|1811819_1813028_-|hypothetical-protein	unknown	unknown	gnl|CDD|376564
CP032698.1|AYG79528.1|1829136_1829910_+|Methionine-aminopeptidase-1	unknown	unknown	gnl|CDD|238519
CP032698.1|AYG79520.1|1822342_1823341_-|F420-dependent-glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|163554
CP032698.1|AYG79512.1|1813409_1814132_+|NAD-dependent-protein-deacetylase	unknown	unknown	gnl|CDD|238701
CP032698.1|AYG79525.1|1827730_1827880_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG79513.1|1814142_1814640_-|Methylated-DNA--protein-cysteine-methyltransferase	unknown	unknown	gnl|CDD|234860

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG79514.1|1814652_1816146_-|putative-bifunctional-transcriptional-activator/DNA-repair-enzyme-AlkA	gnl|CDD|225080	COG2169, Ada, Adenosine deaminase [Nucleotide transport and metabolism].	2.20998e-56
CP032698.1|AYG79517.1|1818869_1819700_+|hypothetical-protein	gnl|CDD|376187	pfam18765, Polbeta, Polymerase beta, Nucleotidyltransferase. A member of the nucleotidyltransferase fold found in polymorphic toxins (NTox45) and polyvalent proteins.	5.89425e-11
CP032698.1|AYG79518.1|1819785_1820613_-|Fructose-1,-6-bisphosphatase/inositol-1-monophosphatase	gnl|CDD|238775	cd01517, PAP_phosphatase, PAP-phosphatase_like domains. PAP-phosphatase is a member of the inositol monophosphatase family, and catalyses the hydrolysis of 3'-phosphoadenosine-5'-phosphate (PAP) to AMP. In Saccharomyces cerevisiae, HAL2 (MET22) is involved in methionine biosynthesis and provides increased salt tolerance when over-expressed. Bacterial members of this domain family may differ in their substrate specificity and dephosphorylate different targets, as the substrate binding site does not appear to be conserved in that sub-set.	6.14207e-57
CP032698.1|AYG79529.1|1829938_1830643_-|hypothetical-protein	gnl|CDD|369321	pfam07335, Glyco_hydro_75, Fungal chitosanase of glycosyl hydrolase group 75. This family consists of several fungal chitosanase proteins. Chitin, xylan, 6-O-sulphated chitosan and O-carboxymethyl chitin are indigestible by chitosanase. EC:3.2.1.132. The mechanism is likely to be inverting, and the probable catalytic neutrophile base is Asp, with the probable catalytic proton donor being Glu. (see the Chitosanase web-page from CAZY).	1.11426e-28
CP032698.1|AYG79527.1|1828563_1828824_-|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	6.51331e-08
CP032698.1|AYG79510.1|1811259_1811772_+|hypothetical-protein	gnl|CDD|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	1.60488e-17
CP032698.1|AYG79519.1|1820781_1821837_+|Octanoyltransferase-LipM	gnl|CDD|319742	cd16443, LplA, lipoate-protein ligase. Lipoate-protein ligase A (LplA) catalyzes the formation of an amide linkage between free lipoic acid and a specific lysine residue of the lipoyl domain in lipoate dependent enzymes, similar to the biotinylation reaction mediated by biotinyl protein ligase (BPL). The two step reaction includes activation of exogenously supplied lipoic acid at the expense of ATP to lipoyl-AMP and then transfer to the epsilon-amino group of a specific lysine residue of the lipoyl domain of the target protein.	3.28865e-62
CP032698.1|AYG79515.1|1816840_1817368_-|O-acetyl-ADP-ribose-deacetylase	gnl|CDD|234759	PRK00431, PRK00431, ADP-ribose-binding protein.	5.17727e-81
CP032698.1|AYG79521.1|1823353_1824757_-|D-hydantoinase	gnl|CDD|236240	PRK08323, PRK08323, phenylhydantoinase; Validated.	0
CP032698.1|AYG79526.1|1828051_1828567_-|RNA-pyrophosphohydrolase	gnl|CDD|240041	cd04685, Nudix_Hydrolase_26, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.87719e-35
CP032698.1|AYG79523.1|1826140_1826983_-|N-carbamoyl-D-amino-acid-hydrolase	gnl|CDD|143592	cd07568, ML_beta-AS_like, mammalian-like beta-alanine synthase (beta-AS) and similar proteins (class 5 nitrilases). This family includes mammalian-like beta-AS (EC 3.5.1.6, also known as beta-ureidopropionase or N-carbamoyl-beta-alanine amidohydrolase). This enzyme catalyzes the third and final step in the catabolic pyrimidine catabolic pathway responsible for the degradation of uracil and thymine, the hydrolysis of N-carbamyl-beta-alanine and N-carbamyl-beta-aminoisobutyrate to the beta-amino acids, beta-alanine and beta-aminoisobutyrate respectively. This family belongs to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), this subgroup corresponds to class 5. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer. Beta-ASs from this subgroup are found in various oligomeric states, dimer (human), hexamer (calf liver), decamer (Arabidopsis and Zea mays), and in the case of Drosophila melanogaster beta-AS, as a homooctamer assembled as a left-handed helical turn, with the possibility of higher order oligomers formed by adding dimers at either end. Rat beta-AS changes its oligomeric state (hexamer, trimer, dodecamer) in response to allosteric effectors. Eukaryotic Saccharomyces kluyveri beta-AS belongs to a different superfamily.	1.7704e-152
CP032698.1|AYG79516.1|1817364_1818789_-|Putative-thiazole-biosynthetic-enzyme	gnl|CDD|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	4.52418e-84
CP032698.1|AYG79522.1|1824860_1826144_-|Acetylornithine-aminotransferase	gnl|CDD|99735	cd00610, OAT_like, Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, alanine-glyoxylate aminotransferase, dialkylglycine decarboxylase, 4-aminobutyrate aminotransferase, beta-alanine-pyruvate aminotransferase, adenosylmethionine-8-amino-7-oxononanoate aminotransferase, and glutamate-1-semialdehyde 2,1-aminomutase. All the enzymes belonging to this family act on basic amino acids and their derivatives are involved in transamination or decarboxylation.	5.55563e-136
CP032698.1|AYG79524.1|1827157_1827658_-|putative-phosphatase	gnl|CDD|319796	cd02612, HAD_PGPPase, phosphatidylglycerol-phosphate phosphatase, similar to Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C. This family includes Escherichia coli K-12 phosphatidylglycerol-phosphate phosphatase C, PgpC (previously named yfhB) which catalyzes the dephosphorylation of phosphatidylglycerol-phosphate (PGP) to phosphatidylglycerol (PG). This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.78154e-15
CP032698.1|AYG79511.1|1811819_1813028_-|hypothetical-protein	gnl|CDD|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	3.64843e-57
CP032698.1|AYG79528.1|1829136_1829910_+|Methionine-aminopeptidase-1	gnl|CDD|238519	cd01086, MetAP1, Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.	1.24601e-107
CP032698.1|AYG79520.1|1822342_1823341_-|F420-dependent-glucose-6-phosphate-dehydrogenase	gnl|CDD|163554	TIGR03842, F420_CPS_4043, F420-dependent oxidoreductase, CPS_4043 family. This model represents a family of putative F420-dependent oxidoreductases, fairly closely related to 5,10-methylenetetrahydromethanopterin reductase (mer, TIGR03555), both within the bacterial luciferase-like monoxygenase (LLM) family. A fairly deep split (to about 40 % sequence identity) in the present family separates a strictly Actinobacterial clade from an alpha/beta/gamma-proteobacterial clade, in which the member is often the only apparent F420-dependent LLM family member. The specific function, and whether Actinobacterial and Proteobacterial clades differ in function, are unknown. [Unknown function, Enzymes of unknown specificity].	0
CP032698.1|AYG79512.1|1813409_1814132_+|NAD-dependent-protein-deacetylase	gnl|CDD|238701	cd01410, SIRT7, SIRT7: Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation. Sir2 proteins have been shown to regulate gene silencing, DNA repair, metabolic enzymes, and life span.	1.24051e-92
CP032698.1|AYG79513.1|1814142_1814640_-|Methylated-DNA--protein-cysteine-methyltransferase	gnl|CDD|234860	PRK00901, PRK00901, methylated-DNA--protein-cysteine methyltransferase; Provisional.	7.16361e-61

Protein sequences

>CP032698.1|AYG79519.1|1820781_1821837_+|Octanoyltransferase-LipM
MHGEYKVPGGKLVVVDLDPRDGVLRDVTVAGDFFLEPDEAILAINGALEGAPADTGAAQLAARIDAALPPGTTFYGLSSEGVAIAVRRALAHATDWNDYDWQLIHEPPQSPALHMALDEVITAEVAAGRRPPTLRVWEWGAPAVVIGSFQSLRNEVDPEGAERHGITVVRRISGGGAMFIEPGNTITYSLSVPDALVQGLSFADSYAYLDDWVLGALGDLGVKAWYQPLNDIATEAGKIAGAAQKRIVADDGAVLHHVTMAYDIDADKMLDVLRIGKEKLSDKGTRSAKKRVDPLRRQTGLSREAVIERMIASFRSRYGLSVGRVTDEEMARARELVATKFSTEGWTARVP
>CP032698.1|AYG79518.1|1819785_1820613_-|Fructose-1,-6-bisphosphatase/inositol-1-monophosphatase
MIDEAFLAGDLTAVQEAVRKAAAAEIMPRFRQLAAHEIVEKNGPHDLVTVADRLAEEHLAASLTAILPGSVVVGEESVHADPAVYDALRGDAPVWIVDPVDGTRQFVRGEAGFCTLVALAHRGELLASWTYAPVLDEMAVAIRGRGATLNGRALHAGSPEPGAVLDVATSHPDYTTPEQKRALLGLRTEGVRPRPCGSAGLEYLAVARGELDGVAFSWEYAWDHAAGLLLVTEAGGAHTTVAGEPFRIAGGNALPFTAARDAATAERIRSLLAGG
>CP032698.1|AYG79517.1|1818869_1819700_+|hypothetical-protein
MNSPADSAFSHHRVSAVAERLVEVRGVVAVALGGSRARGTHRPDSDWDLGVYYRGELDVAALARLAEELTGAPVEVAGPGGWGPWVNGGAWLTLDGVAVDWILRDLDRVESVWAGCLEGRYDVGVQPGHPLGFWSPTYPGEVALGRVLADPARELTALQEATRRYPEPLRAALIAASWEAEFSVEVARKSAGAGDTLHGALCLSRAFGILTQSLHAHDRRWLLNEKGALASAATLPAAPPDFARRVSTALTGLGTDAVGAAGAAAALVSEVREALR
>CP032698.1|AYG79516.1|1817364_1818789_-|Putative-thiazole-biosynthetic-enzyme
MPSMLDAVVVGAGPNGLTAAVELARRGLRVEVFEAKDTVGGGARTEELTLPGFRHDPCSAVHPLGIGSPAFRNMPLERYGLEWLHPELPMAHPFDDGTAAVLSRSVAETAASFGARDAGTYRRLMAPLLGTWDVLARDFMSLPLTALPRDPVGLARFGAVGLQPYSWLMRRFRDDRARALMAGLVAHVIAPLNGVATAGVGMLFALAAHENGWPLPRGGSQSISDALTGYLRDLGGVVHTGFEVKRLDDLPPARTYLFDTSPTALARIAGLGRAYDGYKYGAAVFKIDYALDGPVPWTAEEAKAAGTVQIGPSSRDIATALSQASGGTAPRTPFLITAQPSLVDPSRAPEGKQVFWAYGHVPNGWEGDFTDAIERQIERFAPGFRDRVLARAAAGPPQLAARNANYVGGDIACGAARGLQLLLRPKISLFPYATRHPSVFLCSSAAWPGPGVHGMSGHNAAKAVWRALRKADAR
>CP032698.1|AYG79515.1|1816840_1817368_-|O-acetyl-ADP-ribose-deacetylase
MTARPVDIVLVRGDITEQRVDVIVNAANSSLLGGGGVDGAIHRRGGPAILEECRRLRASHYGKGLATGQAVATSAGRLHAGHVIHTVGPVWSGDEDRSALLTSCYQRSLALARELGAETVAFPAISTGVYGWPLDSGADLAVAAARAYAGPPLREVRFVLFEAAAYEAFDRALRG
>CP032698.1|AYG79514.1|1814652_1816146_-|putative-bifunctional-transcriptional-activator/DNA-repair-enzyme-AlkA
MAPVAPAPMHTDTERCVRAVQSKDARFDGWFFTAVLTTRIYCRPSCPVVPPKVENMTFYPSAAACQQAGFRACKRCRPDTTPGSPEWNARADSVARAMRLIRDGVVDREGVPGLAARLGYSARQIERQLLAELGAGPLALARAQRAQTARLLIETTPLPMAEVAFAAGFSSIRTFNDTVREVFALAPSELRTRAARGVARQTPGAITLRLPFRAPLTPDNLFGHLAATGVPGVEEWRDGSFRRTLSLPYGHGIAELTPQPEHIGCVLRLTDLRDLTIAISRCRWMLDLDADPVAVDDRLRADPLLAPLVDKAPGRRVPRTVDAEEFAVRAVLGQQVSTAAARTHAARLVVAHGQAIDDPTGGLTHLFPTPDRLAELDPQNLALPRSRRTTLTTLVAALADGTLRLGLDSDWDRARAQLMELPGFGPWTVEAIAMRALGDPDAFLPTDLGMRRAAQNLGLPSTPAALTARAAAWRPWRAYAVQYLWATEAHAINHLPA
>CP032698.1|AYG79513.1|1814142_1814640_-|Methylated-DNA--protein-cysteine-methyltransferase
MRITHTVIDSPYGPLTLVAADGVLSRLYMEGQRHRPPQETFGERDDDGPFPEVARQLEAYFTGQLTAFDVDLNMLGTPFQQRVWHQLQQIPYGETRSYGELAEALGNPNASRAVGLANGKNPVGIIVPCHRVIGANGSLTGYGGGLDRKQRLLAFERGRTADVLF
>CP032698.1|AYG79512.1|1813409_1814132_+|NAD-dependent-protein-deacetylase
MGKPLVAILSGAGISTDSGIPDYRGPNGLWRRDPEAEKLVTYSSYMADPEIRRRSWLMRRDSPALKAEPNAAHRAVAELERSGVPVRVITQNVDGLHQRAGLSERKVLELHGTARAVTCTRCHARSSMAEALARVTAGEADPPCTVCGGILKSATVMFGERLDPEVLSQAMAIAKACHLFIAVGTTLQVQPAASLAGIAADGGARLIIVNADPTPYDPLADEVIREPIGTALPRLLRALP
>CP032698.1|AYG79511.1|1811819_1813028_-|hypothetical-protein
MFDTEDVGVFLGLDVGKTAHHGHGLTPAGKKVFDKPMPNSEPKLRAVFDKLTAKFGTVLVIVDQPASIGALPLTVARDAGCKVAYLPGLAMRRIADLYPGEAKTDAKDAAVIADAARTMPHTLRSLELTDEITAELTVLTGFDQDLAAEATRTSNRIRGLLTQFHPSLERVLGPRLDHPAVTWLLERYGSPAALRKAGRRRLVELIRPKAPRMATRLVDDVFDALDEQTVVVPGTGTLDTVVPSLARSLAAVHEQRRALEAQIKALLEDHPLSKVLTSMPGVAVRTAAVLLVTVGDGTSFPTAAHLASYAGLAPTTKSSGTSIHGEHAPRGGNRQLKRAMFLSAFAALHDPASRTYYDKCRARGKTHTQALLRLARHRISVLFAMLRDGTFYEPRVPEAAVA
>CP032698.1|AYG79510.1|1811259_1811772_+|hypothetical-protein
MTTDHSPAPDNAYTAYIAGLPRVLAGAAALFRDAGGKVLLVEPNYREGWALPGGTVESDTAETPRRAARRETLEEIGLDVELGRLLAVDWVHGEARPPIVAYVYDGGVLDDSLLKSIRLQEEELLSWRLVPREELPTHLPGALGHRVMAALDVLAQGQGTAELENGHRVG
>CP032698.1|AYG79520.1|1822342_1823341_-|F420-dependent-glucose-6-phosphate-dehydrogenase
MDFGLVLQTDPPAAQVISLMKRAERNGFRYGWTFDSAVLWQEPFVIYSQILANTRRLTVGPMVTNPGTRTWEVTASTFATLNDMYGNRTVCGIGRGDSAMRVAGRKPNTLARLGEAIGVIRDLAEGREADVDGQRLRLPWVKDGQLPVWMAAYGPKALALAGEKADGFILQLADPFLTEWMVKAVRKAAADAGRDPEAITICVAAPAYVGDDLAHAREQCRWFGGMVGNHVADLVSRYGEHSGLVPESLTAYIKQRQGYDYSHHGRADNPDTTFVPDDIVDRFCLLGPPRAHIDKLKALRELGVDQFAVYAMHDAREAVIDAYGEQIIPALR
>CP032698.1|AYG79521.1|1823353_1824757_-|D-hydantoinase
MSTRTLIRGGLVITAADETHADVLIEDGRIAAIAAHGSSVAQGWTADRVLDATDRYVIPGGVDAHTHMELPFGGTFASDTFETGTRAAAWGGTTTIVDFAVQPRGQALRAGLDAWFAKADGRCAIDYGFHMILSDVNEGSLKEMDRLVEEGITSFKLFMAYPGVFYSDDGQILRAMQRSADNGGLIMMHAENGIAIDVLVEQALARGQSDPRYHGEVRKALLEAEATHRAIQLARVAGAPLYVVHVSAEEALAEIATARDKGLPVFGETCPQYLFLSTDNLAEPGFEGAKYVCSTPLRPKEHQAALWRGLRTNDLQVVSTDHCPFCFTGQKELGRGDFSKIPNGLPGVENRMDLLHQAVVDGHISRRRWIEIACATPARMFGLYPQKGTIAPGADADVVIYDPHAEQTVSAETHHMNVDYSAYEGKRLTGQVESVLSRGETVIDRRTYTGRAGHGCYVPRATCQYLG
>CP032698.1|AYG79522.1|1824860_1826144_-|Acetylornithine-aminotransferase
MTRPLYDRHRAVLPDWLALYYRRPLEITHGEGRHVWDAEGNKYLDFFGGILTTMTAHALPEVTKAVAEQAGRIIHSSTLYLNRQMVELAERIAQLSGIPDARVFFTTSGTEANDTALLLATAYRNSNQILAMRNSYHGRSFSAVGITGNHAWSPTSLSPLQTLYVHGGVRSRGPYAHLGDSQFIEACVADLEDLLGHTRNVAALIAEPIQGVGGFTSPPDGLYAAFREVLNRHGILWISDEVQTGWGRTGDHFWGWQAHARSGPPDLLTFAKGIGNGMSIGGVVARAEVMNCLDGNSISTFGGSPVTMAAGLANLGYLLEHDLQGNARRVGGLLIERLRAIGAQLPLVREVRGRGLMAGIELVEPGTDRANPEAAAAVLEAAREGGLLLGKGGGHDTSVLRIAPPLTLTVAEAEEGAAILERALHSV
>CP032698.1|AYG79523.1|1826140_1826983_-|N-carbamoyl-D-amino-acid-hydrolase
MANVVRAALVQATWTGDTESMIAKHEEHAREAARRGAKIIGFQEVFNAPYFCQVQEPEHYRWAEPVPDGPTVTRMRELARETGMVIVVPVFEIEDEGFYYNTAAVIDADGSYLGKYRKHHIPQVKGFWEKYYFKPGNLGWPVFDTAVGKVGVYICYDRHFPEGWRQLGLNGAQLVYNPSATSRGLSGYLWQLEQPASAVANEYFIAAINRVGREEYGDNDFYGTSYFVDPRGQFVGETASDKEEELLVRDLDFGLIEEVRKQWAFYRDRRPDAYEGLVKP
>CP032698.1|AYG79524.1|1827157_1827658_-|putative-phosphatase
MDTTSRTRPDDRRGRPTAAAFFDVEGTLLAAPDLAAATGPLGRLWHPPVLAALHGHAALGHLVVLVARAGATELAPITRDLAPDAVLCSRPEAPMIGQGKGYAARALLRECGILAARCYAYADEAADLPLLAEVGHPVVVGDDPVLLRHARRGNWRRLPAPSAERK
>CP032698.1|AYG79525.1|1827730_1827880_-|hypothetical-protein
MLLNHLQNRLHLALPATRNLAEQQRPGGTDDLFVAWETLTHAQNPGAPV
>CP032698.1|AYG79526.1|1828051_1828567_-|RNA-pyrophosphohydrolase
MSPAPTRTPRRAARVVVRDAQGAVFLLRYDNEEVGPHWAMPGGGLDPGESPREGALRELREETGWTDLEPGPLLCTWTHDFTRAGVPVRQFEHIYLADAPGPVRELGPDVADQHRADRILGWRWWTPEELRHTDEQIWPPQLHALLDAWSPGDPPAELGHVPLKGLPDTVG
>CP032698.1|AYG79527.1|1828563_1828824_-|hypothetical-protein
MVRTPLTPAERERGERLGRLLRSARGQRSMTEIAAAAGLSAETLRKIETGRAPTPAFFTVAALASVLGLSMDEIVTDCAPPPAVAA
>CP032698.1|AYG79528.1|1829136_1829910_+|Methionine-aminopeptidase-1
MGMVKIKSDTQMDAMREAGRVVAHALAAARNAAGVGVELRALDAAARDVLFKAGATSPFLDYHPDFAPVPFPATACVSVNDAIVHGIPDDYRLRDGDLVSVDYGAILDGWAGDSAISFTVGRARPEDVRLVETAFRALDAGIAAAVVGGRIGDIAHAIGTVCRSAGYGIPDGFAGHGIGRDMHEDPGVPNEGRAGRGMVLRHGMVLAIEPMVIGDGSDGYYPAADGWTLRTLSGARAAHAEHTVAVTDAGPRVLTLP
>CP032698.1|AYG79529.1|1829938_1830643_-|hypothetical-protein
MRTRTLALSTAFGAALLTAAALPATARDGLVAAPPARADEGPVRAAELLAKVTSCSQVSRGKFRTDPGAAATVPVCGLNGAVFWKADLDVDCDGQPTAACNNKTDPWFQPDTRFHQANDKPLNAEKVPYVVVPGAGSLWDYGSAGVTGGTVVAVVYDNKVEYAVVGDTGPSTTIGEASYATAKALGMNPDPRTGGAESGVTYILFQHSQATPIESHGAAATLGQALAQEFLADN

Crispr_ID: CP032698_6

• CRISPR_ID: CP032698_6
• CRISPR_location: 1978266-1978366
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_6

Consensus_repeat	Method
TCCCTGGGGCTCCGCCCCAGACCCCG	CRISPRCasFinder

spacers of CP032698_6

>6.1|1978292|49|CP032698|CRISPRCasFinder
GGCACCTCGCCCACCCACCCGCCCGTTACGGGGGTTGGATAGCCCCGGG

CRISPR arrays and Neighbor proteins around CP032698_6

CRISPR arrays

The CRISPR arrays of CP032698_6

>merge|CP032698|6|1978266-1978366|CRISPRCasFinder
TCCCTGGGGCTCCGCCCCAGACCCCGGGCACCTCGCCCACCCACCCGCCCGTTACGGGGGTTGGATAGCCCCGGGTCCCTGGGGCTCTGCCCCAGACCCCG

>CP032698|6|6|1978266-1978366|CRISPRCasFinder
TCCCTGGGGCTCCGCCCCAGACCCCG	GGCACCTCGCCCACCCACCCGCCCGTTACGGGGGTTGGATAGCCCCGGG
TCCCTGGGGCTCTGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG79652.1|1975675_1976776_-|Sodium-potassium/proton-antiporter-ChaA	unknown	unknown	gnl|CDD|223464
CP032698.1|AYG79658.1|1984755_1985547_-|hypothetical-protein	unknown	unknown	gnl|CDD|214802
CP032698.1|AYG79654.1|1978769_1979918_-|Small-ribosomal-subunit-biogenesis-GTPase-RsgA	unknown	unknown	gnl|CDD|234988
CP032698.1|AYG79648.1|1970115_1970598_+|hypothetical-protein	unknown	unknown	gnl|CDD|377293
CP032698.1|AYG79656.1|1981399_1982788_-|hypothetical-protein	unknown	unknown	gnl|CDD|378342
CP032698.1|AYG79657.1|1982778_1984749_-|Lipid-A-export-ATP-binding/permease-protein-MsbA	unknown	unknown	gnl|CDD|224055
CP032698.1|AYG79647.1|1968614_1969598_+|hypothetical-protein	unknown	unknown	gnl|CDD|224296
CP032698.1|AYG79646.1|1964647_1968424_-|Intracellular-serine-protease	unknown	unknown	gnl|CDD|173812
CP032698.1|AYG79659.1|1985540_1986119_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG79644.1|1960544_1962287_-|Pyruvate-dehydrogenase-[ubiquinone]	unknown	unknown	gnl|CDD|180614
CP032698.1|AYG79651.1|1973656_1975495_-|Asparagine-synthetase-[glutamine-hydrolyzing]-3	unknown	unknown	gnl|CDD|273676
CP032698.1|AYG79662.1|1987504_1988716_+|Anaerobic-sulfatase-maturating-enzyme	unknown	unknown	gnl|CDD|223714
CP032698.1|AYG79660.1|1986131_1986878_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG79650.1|1971273_1973574_+|hypothetical-protein	unknown	unknown	gnl|CDD|379232
CP032698.1|AYG79649.1|1970696_1971065_+|hypothetical-protein	unknown	unknown	gnl|CDD|274925
CP032698.1|AYG79645.1|1962314_1963736_-|hypothetical-protein	unknown	unknown	gnl|CDD|379325
CP032698.1|AYG79653.1|1976831_1978202_-|putative-bifunctional-transcriptional-activator/DNA-repair-enzyme-AlkA	unknown	unknown	gnl|CDD|225080
CP032698.1|AYG79661.1|1987112_1987508_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG79663.1|1988803_1989697_-|hypothetical-protein	unknown	unknown	gnl|CDD|225360
CP032698.1|AYG79655.1|1980201_1981380_+|Cytochrome-P450-107B1	unknown	unknown	gnl|CDD|225035

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG79652.1|1975675_1976776_-|Sodium-potassium/proton-antiporter-ChaA	gnl|CDD|223464	COG0387, ChaA, Ca2+/H+ antiporter [Inorganic ion transport and metabolism].	4.86501e-79
CP032698.1|AYG79658.1|1984755_1985547_-|hypothetical-protein	gnl|CDD|214802	smart00752, HTTM, Horizontally Transferred TransMembrane Domain. Sequence analysis of vitamin K dependent gamma-carboxylases (VKGC) revealed the presence of a novel domain, HTTM (Horizontally Transferred TransMembrane) in its N-terminus. In contrast to most known domains, HTTM contains four transmembrane regions. Its occurrence in eukaryotes, bacteria and archaea is more likely caused by horizontal gene transfer than by early invention. The conservation of VKGC catalytic sites indicates an enzymatic function also for the other family members.	2.56362e-11
CP032698.1|AYG79654.1|1978769_1979918_-|Small-ribosomal-subunit-biogenesis-GTPase-RsgA	gnl|CDD|234988	PRK01889, PRK01889, GTPase RsgA; Reviewed.	0
CP032698.1|AYG79648.1|1970115_1970598_+|hypothetical-protein	gnl|CDD|377293	pfam04306, DUF456, Protein of unknown function (DUF456). This family is a putative membrane protein that contains glycine zipper motifs.	6.27144e-15
CP032698.1|AYG79656.1|1981399_1982788_-|hypothetical-protein	gnl|CDD|378342	pfam09992, NAGPA, Phosphodiester glycosidase. This is a family conserved from bacteria to humans. The structure of a member from Bacteroides has been crystallized and modelled onto the luminal region of the human member of the family, the transmembrane glycoprotein N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. There is some conservation of potentially functional residues, implying that in the bacterial members this family acts in some way as a phosphodiester glycosidase. The human protein is also present, so the eukaryotic members are likely to be catalyzing the second step in the formation of the mannose 6-phosphate targeting signal on lysosomal enzyme oligosaccharides.	2.09192e-22
CP032698.1|AYG79657.1|1982778_1984749_-|Lipid-A-export-ATP-binding/permease-protein-MsbA	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.65524e-83
CP032698.1|AYG79647.1|1968614_1969598_+|hypothetical-protein	gnl|CDD|224296	COG1378, COG1378, Predicted transcriptional regulators [Transcription].	1.1448e-10
CP032698.1|AYG79646.1|1964647_1968424_-|Intracellular-serine-protease	gnl|CDD|173812	cd07487, Peptidases_S8_1, Peptidase S8 family domain, uncharacterized subfamily 1. This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.74152e-76
CP032698.1|AYG79662.1|1987504_1988716_+|Anaerobic-sulfatase-maturating-enzyme	gnl|CDD|223714	COG0641, AslB, Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only].	3.92008e-40
CP032698.1|AYG79644.1|1960544_1962287_-|Pyruvate-dehydrogenase-[ubiquinone]	gnl|CDD|180614	PRK06546, PRK06546, pyruvate dehydrogenase; Provisional.	0
CP032698.1|AYG79651.1|1973656_1975495_-|Asparagine-synthetase-[glutamine-hydrolyzing]-3	gnl|CDD|273676	TIGR01536, Asparagine_synthetase_1, asparagine synthase (glutamine-hydrolyzing). This model describes the glutamine-hydrolysing asparagine synthase. A poorly conserved C-terminal extension was removed from the model. Bacterial members of the family tend to have a long, poorly conserved insert lacking from archaeal and eukaryotic sequences. Multiple isozymes have been demonstrated, such as in Bacillus subtilis. Long-branch members of the phylogenetic tree (which typically were also second or third candidate members from their genomes) were removed from the seed alignment and score below trusted cutoff. [Amino acid biosynthesis, Aspartate family].	1.94544e-145
CP032698.1|AYG79650.1|1971273_1973574_+|hypothetical-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	7.62899e-05
CP032698.1|AYG79649.1|1970696_1971065_+|hypothetical-protein	gnl|CDD|274925	TIGR04023, Pyridoxamine_5'-phosphate_oxidase, PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomycetales, make F420. This subfamily within the PPOX family occurs in at least 19 distinct species of F420 producers and is likely to bind F420 rather than FMN. The member OxyR was shown to use F420 to catalyze a C5a-C11a reduction in oxytetracycline biosynthesis. [Unknown function, Enzymes of unknown specificity].	4.17841e-58
CP032698.1|AYG79645.1|1962314_1963736_-|hypothetical-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	1.11825e-14
CP032698.1|AYG79653.1|1976831_1978202_-|putative-bifunctional-transcriptional-activator/DNA-repair-enzyme-AlkA	gnl|CDD|225080	COG2169, Ada, Adenosine deaminase [Nucleotide transport and metabolism].	2.50185e-57
CP032698.1|AYG79663.1|1988803_1989697_-|hypothetical-protein	gnl|CDD|225360	COG2771, CsgD, DNA-binding HTH domain-containing proteins [Transcription].	1.02622e-14
CP032698.1|AYG79655.1|1980201_1981380_+|Cytochrome-P450-107B1	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	2.91461e-94

Protein sequences

>CP032698.1|AYG79653.1|1976831_1978202_-|putative-bifunctional-transcriptional-activator/DNA-repair-enzyme-AlkA
MDHDAAYEAVTSRDARFDGEFFFAVATTGIYCRPSCPAVTPRRKNVRFFPSAAAAQNHGFRACRRCRPDAVPGSAEWNARADVVGRAMRMIGDGVVDREGVPGLATRLGYSARQVQRQLTAEVGAGPVALARAQRAHAARVLLQTTSLPVTEIAFASGFASVRQFNDTIRQIYARTPSGLREEAGTRATRAGVAAAAGIPLRLAHRGAYAVKETFDLLAAEAVEHVEEVAGASGARTYRRTLGLPHGTAVVAVDEAAPAHTAARQGWLDARIHLTDLRDLTTAVQRLRRLFDLDADPYAVDERLGADPRLAPLVARTPGLRSPGAADPEECAVRALIGQQRAAGLVETYGKRLDVPCGTLTHLFPDSATLAPHPDPHLAALATALADATLRLDAGADRDEAARVLRTLPGMDEETVQVIRTRALGDPDVGPADRDAWRPWRSYARRHLAVAAAGRR
>CP032698.1|AYG79652.1|1975675_1976776_-|Sodium-potassium/proton-antiporter-ChaA
MIRLARLPLDRWSAVMPPLAVVLLALTWGRSLPGVLVALVACFLAGAVLAAVHHAEVVAHRVGEPFGSLVLAVAVTIIEVALIVTLMSDGGDKSASLARDTVFAAVMITCNGIVGVCLLVGAVRRRLAVFNAEGTVTAFATVTTLAGLSLALPTFTTSKPGPEFSPAQLIFAAIASVFLYGLFVATQTVRHRDYFLPVTQQGEVMRDDAHANPPSARTAWTSVILLGVALVAVVGLAKGVSPTIERGVAAAGLPASVVGVVIALLVLLPETIAAVRAARRDRVQTSLNLALGSAMASIGLTIPAVALATIWLSGPLVLGLGASHMVLLALTVAVGILTVVPGRATLMQGGVHLSLFAAYIVLAVSP
>CP032698.1|AYG79651.1|1973656_1975495_-|Asparagine-synthetase-[glutamine-hydrolyzing]-3
MCGITGWISFDRELRAERETLDAMTETMECRGPDDRGVWAGGPAALGHRRLAIIDLPGGRQPMTVEADGKTVALVYSGEAYNFTELKAELASRGHRFHTDSDTEVVLHGYLEWGEAVAERLNGMYAFAIWDERVQRLVMIRDRMGIKPFYYYETPDGVLFGSEPKAILANPLARRSVSLDGLRELLTLVKTPGHAVWDGMKEVEPGTVVTVDRGGLRTHTYWKLETRPHEDDRATTVARVRELLDDIVRRQLVADVPRCMLLSGGLDSSALTAIAARQLGEVDEKVHSFAVDFVGQTENFVADDLRGTPDTPYVHDVARASGTLHQDIVLDARSLADPEVRAKVIRARDLPISFGDMDASLYQLFKAIREHSTVALSGESADEVFGGYKQFFDEDARSADTFPWLVNFVEQFGDSDLLRPELSAALNVPAYVKDSYNTAVAGVQRLDGESDFEYRMRRSSHLHLTRFVRVLLDRKDRASMAVGLEVRVPFCDHRLVEYVYNAPWSLKSFDGREKSLLREATRDVIPRSVYDRVKSPYPSTQDPEYVTVLQGHAKDLLARTSHPVFDLIDRDGLRRATEASAPQIPRASRRDLEYSLDLAIWLDLYKPELKLA
>CP032698.1|AYG79650.1|1971273_1973574_+|hypothetical-protein
MHPSAPPSRTRSPRSTGGSRRLVTAATLLALAVTAGPFASPAVAAPPAVPTASGAATAPHAATFKIAADAQVLSAGRTGFLSLAKSGSGHDLLWTRYADGQTTVVVKDAPSYASLPAFHGASSDMVALRDDAGTKVTLLDMTTGTSNVIDLAPYDYFYLGTVGSHVLASKQIGDTVEPHVLDVVDQKVTDRVITGLPASAREVDVEAGSGDFAALRYSTSSTSSEFFDYVAADLSSAKAVPGNSMLGGYITKAAVSPTHLALVGGLFTSDTSSSVRTMELGGDQKRWNMNLDHKQGDGLVGLVGGWSLYGASRTLNEGNDLTDSALHATPIGGGTERTVMDHASSLAPAPDGSLLVMGGTAAEGEGLYRVVTGSDRAPVAQLLSGTGHPTKLIVEESQVPAVAALDKAPWRPKWRLTHNNTDVTVTLRHTASGAQREIELRVDPAQWESTDPAWRELDWDGLMGPSYSPNTAAPNGGYTWTLAAKPRNGIGPDLVRSGAFTVSRKATPHDFTDNGSPDLLIRDGLGTLQRRDTYREPGTGKLKGGEAATIGSDWDIYNQVTAVGDVAGGPVGDVVARDKSGILWLYLGKGDGTLDTRVRIGSGWGEYNQLTGGGDVSGDGRSDLLARDSHGVLWLYKGNGNWRAPFAPRVKAGTGWDMYNQVTAVGDVAGGPGGDLVGRDKDGVSWLYLGKGDGTFESRVRIGAGWGEYTQTVGIGDCDGDGRADVFVTTSTGDSYVYRGTGNWRAPFAPREATGLYPLSFDETIS
>CP032698.1|AYG79649.1|1970696_1971065_+|hypothetical-protein
MTEFSEAERAYLKTQRLGRLATVDGKGQPQANPVGFFPQDDGTILIGGYALGTTKKWRNLRGNPKAALVIDDVVSVTPWKVRGVEIRGTAELLTGPHELGPHFSEELIRIHPEKIHSWSLDQ
>CP032698.1|AYG79648.1|1970115_1970598_+|hypothetical-protein
MGVWQVVGVGAVMAMGLCGVLVSGVPGPAIVWAALAWWALDDITALAWGVLAGATGVLLLNQALRPLLPPRRFKAAGVSRRAVFTAGATAVVGFFVLPVIGGLAGFVGGLYGAERRRLGSHGDGWTSARMVLRAGGYSVMAELFACLLVAGAWLGAVIWG
>CP032698.1|AYG79647.1|1968614_1969598_+|hypothetical-protein
MVLGAIGLDETQESAYRALVAVGAAEVTDLAHRLALPENETERALRRLERHGLAAQSSARTGRWVAAPPGVALGALLTQQRHELDQAELAAALLASEYRAEAAEPAVHDLVEVVTGASAVSHRFHQLQLGAAEEVCALVTGKPVAVTGMDNESEERASIRGVAYRVVIEREVLSLPAGIVELSAALGRDEQVRTVERVPTKLVVADRSLAMVPLTGRDAEPAALVVHASGLLESLMGLFEAVWKDALPLRLGGGDRGIVEETPGPDATDLEILSLLLAGMTDASAAKQLEVGLRTVQRRVKGLMELTGVTTRLQLGWHAYERGWVTR
>CP032698.1|AYG79646.1|1964647_1968424_-|Intracellular-serine-protease
MRPISRTALGVAAAAALAVTAVAPSVAAPRHDDTASTAERPLVGGATSGTGQPATVTLVTGDKVVVSRDRSGAPTGVTALPREDGSVPLVQTRRSGQELYVYPDGAAGALAAGSVDEELFNVSGLIRQGYDDAHTKTLPLIAVYDHAAPRSARAVPRGAKAGLNLPAVNGTALTVDKVSAAHLWADVANSRTRAASSGIKKLWLDRKVTATLDRSARQIRADLAWAAGYDGKGTKVAVLDTGVDAEHPDLKGRVTDAKNFTDSPDTEDRQGHGTHTTSTVGGSGAASDGKKKGIAPGTGLMVGKVLNDSGSGDSSWIIAGMQWAVDNKADVVSMSLGSPVPTDCTDPMSIAAQELATSAPHTLFVVAAGNSGPGLNTVSSPGCAPGVLTVGAVDRDDTTAGFSSRGPAPFTHTLKPEITAPGVGISAANAGGRGVYAYQTMSGTSMATPHVAGAAAIVRQRHPDWSAQQIKAALVSSADSAIPGDVRETGGGRLDVKAAIDTTVLGAPAVQAGTFDWPQDKSDRTTVDVPYTNLTDKPLRLDLKVAGVTGNDGSPVNSRVAKLSSGTVTVPAGATAKVPLAIDPTARLAAGQYGDVTGRVLATANGVQVSTPFALYVEPETLTLRVKLVDRQGGPAAGASSLDVIGTDTATGERRFNDGATDQVYRLRPGAYFVSSFVTSPDPGDATGADVGSVSYLGRPQLDLKKDTTLVLDARSAHRLSLRTERPSEVRTTTLDFARSWGGQWLHSGSLSGSRLIKEYFADVRGDARTGDFEFGSYWRAYAPQFDRLGVVGGPELHPLTASVGSDNLDGTGRAPLVDAGRGTPEELKAAGVAGKVAFVAVPDGAGSLSTLGKDAKAAGATALLVHRPSAGRWLPAYGFTGGPLPTLSVEAAEAKALTDRLSGGPVTLTWKATAKSGYVYNLGFQEDGGFDSDRVYRVRDGQLGRNASTYHSMGVPADFVDGVAAHRPDGRAIGVSGIDLVAVPSTRTEFYTPGPTTWDHFVSSSFPFGEFMLSPPTAYRAGKQTKESWYDGVVGPDAGRDGTGEPLLAAERQGDLIGFAPGMWGDTEHSAQPGSFGDIGSLLLRRDGKDYDSSGWPSGVFTVPADDAAYELISDNQKIGPSGAVWKRSTETVTSWKFRSHREEKVYSQGIPLLFPHYDVPDDALKTVPAADGQKIGLTVTGHAGYTPAGLVSAALSYSYDGGATWTKANSVHQGGSWMATVNHAGASAKNVTLRAELTDANGNSVTQTVVNAYAVR
>CP032698.1|AYG79645.1|1962314_1963736_-|hypothetical-protein
MPPPIGDPDAVPSAPEPRSRAPWEAPEGAHAPRGAVAWWEAVPAAPPPPAEPAPLPDLPPGWAEDASPDAPHSPGARPPAPASPGAGGEEPFAGDAPHSPRARPPARIGDEEPFAGNAPRTPTLDASGPPLTAPDEQFAQPARFTSLPRPRTGHVGDGPPTYDAEPTALPAARPEELDDLVADTVLDGARYGTYVLRAVSARGDSARYRGEARRDALLTARFGTGENALVLVAVASGVRTSERAQLAAADACHWIGGAIGRSHVRLAEDIRAGRRGDLKSGLHRLTDRSYGMLRARAAELGAGPEEYTAHLRCLLLSADPACRTRVFFGVGHGGLFRLRGGVWQDIEPAVPEPGEVLGEPVVGFGSAPAETPAGDRLTMDLGTVEPARPYIDPPVPPGEPFRFRASVARPGDTLLLCSAGLAEPLRGEAALAEELAERWAAAEPPGLAAFLADVQLRVKGYADDRTAVAVWEA
>CP032698.1|AYG79644.1|1960544_1962287_-|Pyruvate-dehydrogenase-[ubiquinone]
MAKQNVAEQFVDILTRAGVQRMYGVVGDSLNPVVDAIRRNSAIEWIQVRHEEVAAFAAGAEAQLTGKLAACAGSCGPGNLHLINGLYDAHRSMAPVLALASQIPSSEIGLGYFQETHPEQLFRECSHYCELISSPQQMPRVLQTAIQHAIGRGGVGVLALPGDIASAPAPDKAIDHALVTSRPTVRPGDAEIAQLAALVDAARRVTLFCGSGTAGAHAEVMEFAGRIKSPVGHALRGKEWIQYDNEYDVGMSGLLGYGAAYEATHACDLLILLGTDFPYNAFLPDDVKIVQVDVRPEHLGRRSKLDLAVWGDVKETLRCLIPRVKEKTDRRFLDKMLKKHADALEGVVKAYTRKVDKHVPIHPEYVASVLDELADDDAVFTIDTGMCNVWAARYISPNGRRRIMGSFSHGSMANALPQAIGAQFVDRRRQVISMSGDGGFSMLMGDFLTLVQYDLPVKIVLFDNSSLGMVELEMLVAGLPSYGTTNHNPDFAAIARAAGAYGVRVEKPKQLAGALKDAFRHKGPALVDIVTDPNALSIPPKISAEMVSGFALSASKIVLDGGVGRMLQMARSNLRNVPRP
>CP032698.1|AYG79654.1|1978769_1979918_-|Small-ribosomal-subunit-biogenesis-GTPase-RsgA
MSSSFSTPFNTSAFGTSGFNTSAPSRPLAAYGWDDAWAAEFTPYAEQGLVPGRVVRVDRGQCDVATADGTLRADTAYVTPHDPMRVICTGDWAVVEPGGDPRFVRAYLPRRTAFVRSTSSNRSEAQILAANVDHAIIAVSLAVELDLGRIERFLALAWESGAQPLVVLTKADLVPDPVGLSYLVRDVETAAPGVQVLPVSATTREGIDILAAVVAGGTSVLLGQSGAGKSTLANALLGAEVMVVQAIRDVDGKGRHTTTTRNLLVLPGGGVLIDTPGLRGVGLYDAESGVGQVFAEIEELATDCRFHDCAHQAEPGCAVLAAIEDGSLSERRLDSYRKLLRENQRIVAKTDARVRAELRREWRLRGAEGRANGVLKRGRGVS
>CP032698.1|AYG79655.1|1980201_1981380_+|Cytochrome-P450-107B1
MNDPTQDPRFHQDPYPAYAALRSRCPVQRLANGPDGRASYVVTGYAEAREALADARLSKDTAAFFAGKGSSRRLHPAVARTMLASDPPRHTRLRKLVTKAFTTGAVAELRPFIAHVTDELLDRWPVGQQADFVADLAVPLPVAVICELLGVPQDDRPDVRRWSGELFAAGRPDVIDAASHALADYMTNLIAAKRLRPGERLLDRLIAARDGDDRLSEEELVSLAVLLLVAGHETTTHFLGNAALALLRHPAALDRLRADPDGIRTLLDELLRYDSPVSTATFRFTTEAVTLGGTDIPAGVPVLVALGAANRDPRRFPSPDLLDRDRDAAGHLGFGHGIHRCVGAPLALAEAEIALRAALVRFSRLRLAVAFERLQWRRTRLVRGLTSLPVLT
>CP032698.1|AYG79656.1|1981399_1982788_-|hypothetical-protein
MPLTVARFSGATRGAPARVSPGDRHARLPSRVPHRHHGGGMNRVRIAVAAVFLLTLTTTLTVGAGRPARATDAARDPALQHIAPALQHIDPAVEHIAPGVDYQALTLTTGHGPSRVHVVTVDLRHAGVGAGLLHAGTVTGRAPVSAMAEQQGAVAAINGDFFNMTEAEHPGVAATGSASGAAVLHGQPLKGAVPQGQRFGWKMPAGASGEDVLGVGQDGRARTARLTLNGQLHPPQGSLALKGLNQYALPEGSIGVFNPDWGSVSRARAACGTDHKRAAPCTRDTFEVTVRDGRVADTATTPGSGPVPAGSLVLLGREQGARALRSLTPGTPVSVDYRFDSTGVTPFDFALGAYPLLKDRAPLPGLDDVTAEPRTAAAIADDGHLLRLVATDGRESTATGLTVAELARFLASLRCDEGVFLDGGASTTLVTRDPATGRTTVRNTLDHGQQRRVPNGIAIYHH
>CP032698.1|AYG79657.1|1982778_1984749_-|Lipid-A-export-ATP-binding/permease-protein-MsbA
MRRPRRDRTAPAPDEDAQRPSDSEQLLFGGPLRYDTGWSQHEEAYLALNLRAVLRRLPRLLASGFRLAWRADPRAARGLVAANLGRGLTQAASLLAVNRVLAGLMTGGTMEERLRGVLGALVAVGVCLSAGALLRAVSTYATGRLEPRVERMATEVYLERASRVELAAIEDDQFHKLLDSARYGASSARRMMSIGNRVISAAISFVTAAGVLTVLHPVLLPLLTVMTLPGSWSALTTARRRYLSFHAWTQHTRAGALIGQMLTDAGAAPEIRVHGVGPFLLRHFRALAESAEAEQSRLARLEARTGLIAAGWIGVATAATYATLGALLLGGAMALSVAGTAVIAIRTGSASLTTLALEVNALHEQALFVGDLERLCEEAERRTRAPGGVALPEAPRLIRFEQVTFTYPGEGTPALDDVTLTLPTGRIVALVGSNGSGKTTLARLLAGLYAPQRGRILWDDVDAALADRRQLTDRVAMVAQDFTRWAFTARVNVLIGRPEAPAHDEHVERALRHAGAEDLVAGLPRGLDTLLARGFRGGHQLSGGQWQRLGFGRAAYRAAGRPGQILIVDEPTAALDARAELQIFDEIRSLAEDGSTVLLITHRLASVRHADLVHVLDEGRLVESGAPADLLAAGGLYAELYHLQANQYAPEDETCR
>CP032698.1|AYG79658.1|1984755_1985547_-|hypothetical-protein
MLNETETARAILAVCGVGLAVSAGRDLRQSHEFGAGGALAWAVVGAYPHRCPPAVRALFVGDRYRAVLAVQCAAGLAAPAVAALSAPGSAVVACVLLTTLLLGLHRSDYGTDGADQMAALAMLTAAVTLTVGGTVGRLFLAFLTGQLILSYLIAGVAKLVSPTWRDGSCLAQILSTDSYGSPGIAAFLRARPWVGALMAWGVMVLEVTFWLALVVPGPPRWGLLAAGAALHLGIAFTMGLTTFVFAFIGAYPALVFTAAALTG
>CP032698.1|AYG79659.1|1985540_1986119_-|hypothetical-protein
MVPALVAVVLAGWLLLTVVAALPRIGTATQRHVPDWFAPLLPAWTFFAPNPATKDKVLMYRDILANDTVGPLRLVLPEGGAGGRPGKALFDAASQLLRRAAAGWDEEPDARIRDARLMISTPYLLLLNRAATAPHDATAVSFEFVIAHASRRDEEPEVVFVSAVHRLKGAAGSGAVAHGGPGRRAVREGTPC
>CP032698.1|AYG79660.1|1986131_1986878_-|hypothetical-protein
MMLASTTAAAVKSVQVVTVPTDAAGVADGGLLPPAGTVVIYVGDAAAPEWHRLRAAALDGDWQAVRDTAVPQHPNPGAELTAASTPFDLVCAGHVVAHGLALPHGVPFRTLTFPYTGGPIRDADFGIVEHTDGGTPAVRTTCLLMRRAPELTRLERQLLDDMDPEERHVHMRRPQPCQTLTAMDALTDGIGRAAQEAVREKHARGGYARDESATALSQSEITEIAGESGEPAAAVADLLATRRRHFSY
>CP032698.1|AYG79661.1|1987112_1987508_+|hypothetical-protein
MAESKRDIREPGSHEPNSPSRSAYLRLLALQRAGEPTAPAGVEEAGQQPERLERQAIVDELRPPVRMWPDYPDFWVESPRGGGPWHERFGDKGPRRSGSVARRGGQEPAPSRMSVSEAFLRLRLTLGAEPA
>CP032698.1|AYG79662.1|1987504_1988716_+|Anaerobic-sulfatase-maturating-enzyme
MSVDASPQRGEVGAAGREPMPPYLQLVVKVSKFCNLRCRYCYEFPSLGDRAAMTVEQVRNMIRHVGEWLADQPGRTADFVWHGGEPLLMPPDFYREVKRAQEEFLEPASIPYGNSVQTNLYRLTDDDLALMRDVFDDVGVSVDLVGGQRVNVAGRQAQPRVLAHMQRLMDEGLNFGCITVLSRSTAPHVAEIHRFFEDMNLGFRMLPIYRTGYPGQQAEHELSAQEIVEAFKTLTDRWLVSDSFINVEPIEGYAAQVVHALSGADNRRYYDKELSETILVIDTDGSVYSNGDAYDPALCHGNIFTDSLSSTRRSASFAEALRQSRQRVTDTCTGCRFHGSCSGFFAAESTPEQRWRDPATGLSVCGVVLPVQEYIEERLTALGLVDGVTRRLDRALLERRALD
>CP032698.1|AYG79663.1|1988803_1989697_-|hypothetical-protein
MPDLRGSVTEAEEFRRQLLAAAARATTVAELATELSRLLHPFLPHDGHTLAGLDPLTGVGCLHHDLRPSKGPGSELPIALTLRGRVWGGLVLLRGGDGTPFSEAEARCAERLAGPLSAALRQYVAGKPLRPGRRGLFPGVIVIGPDDTIKGMTSTARTWLHEFLPETPPAKDDELPHLLWGITYFTRRTHTTALSRIPTGGGWVAVHAQLLDGKEEGDIVITFQSAPASQLLPAIFVWYGFTPREQAIVECLLGGLATKRIARLLGMSPHTVSGHLRSVYRKTGTGGREELIAGLRQ

Crispr_ID: CP032698_7

• CRISPR_ID: CP032698_7
• CRISPR_location: 2066121-2066220
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_7

Consensus_repeat	Method
CCCCTGGGGCTCCGCCCCAGACCCCG	CRISPRCasFinder

spacers of CP032698_7

>7.1|2066147|48|CP032698|CRISPRCasFinder
GGCACCTTCCCCACCCACCCGCCCGTGCCCCGGGGTTGGATGGTTCCG

CRISPR arrays and Neighbor proteins around CP032698_7

CRISPR arrays

The CRISPR arrays of CP032698_7

>merge|CP032698|7|2066121-2066220|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCGGGCACCTTCCCCACCCACCCGCCCGTGCCCCGGGGTTGGATGGTTCCGACCCCCTGGCTCCGCCCCAGACCCCG

>CP032698|7|7|2066121-2066220|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCG	GGCACCTTCCCCACCCACCCGCCCGTGCCCCGGGGTTGGATGGTTCCG
ACCCCCTGGCTCCGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG79739.1|2080264_2081464_-|N-acetylglucosamine-repressor	unknown	unknown	gnl|CDD|224851
CP032698.1|AYG79727.1|2063069_2063723_+|hypothetical-protein	unknown	unknown	gnl|CDD|378665
CP032698.1|AYG79729.1|2064741_2066025_+|Ribonuclease-D	unknown	unknown	gnl|CDD|223426
CP032698.1|AYG79721.1|2055581_2056388_+|hypothetical-protein	unknown	unknown	gnl|CDD|275063
CP032698.1|AYG79738.1|2079027_2080143_-|D-xylose-binding-periplasmic-protein	unknown	unknown	gnl|CDD|380650
CP032698.1|AYG79733.1|2071408_2072920_-|hypothetical-protein	unknown	unknown	gnl|CDD|224720
CP032698.1|AYG79731.1|2067799_2069932_+|Fatty-acid-oxidation-complex-subunit-alpha	unknown	unknown	gnl|CDD|236864
CP032698.1|AYG79735.1|2074635_2076594_-|1-deoxy-D-xylulose-5-phosphate-synthase	unknown	unknown	gnl|CDD|183601
CP032698.1|AYG79724.1|2058892_2060323_-|Protoporphyrinogen-oxidase	unknown	unknown	gnl|CDD|237009
CP032698.1|AYG79734.1|2072993_2074487_-|putative-amino-acid-permease-YhdG	unknown	unknown	gnl|CDD|129987
CP032698.1|AYG79720.1|2054766_2055555_+|hypothetical-protein	unknown	unknown	gnl|CDD|379301
CP032698.1|AYG79725.1|2060531_2061908_+|NADH-oxidase	unknown	unknown	gnl|CDD|181958
CP032698.1|AYG79726.1|2061911_2063003_-|Uroporphyrinogen-decarboxylase	unknown	unknown	gnl|CDD|234644
CP032698.1|AYG79728.1|2064000_2064663_+|Transcriptional-regulatory-protein-DegU	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG79730.1|2066576_2067803_+|3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA-thiolase	unknown	unknown	gnl|CDD|273881
CP032698.1|AYG79723.1|2058171_2058888_-|Putative-heme-dependent-peroxidase	unknown	unknown	gnl|CDD|377705
CP032698.1|AYG79736.1|2076738_2078043_-|Xylose-transport-system-permease-protein-XylH	unknown	unknown	gnl|CDD|226669
CP032698.1|AYG79737.1|2078039_2078828_-|Xylose-import-ATP-binding-protein-XylG	unknown	unknown	gnl|CDD|224053
CP032698.1|AYG79732.1|2070081_2071233_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG79722.1|2056494_2058093_+|Tripeptidyl-aminopeptidase	unknown	unknown	gnl|CDD|312032

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG79739.1|2080264_2081464_-|N-acetylglucosamine-repressor	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	2.80076e-67
CP032698.1|AYG79727.1|2063069_2063723_+|hypothetical-protein	gnl|CDD|378665	pfam11452, DUF3000, Protein of unknown function (DUF3000). This is a bacterial family of uncharacterized proteins.	1.57771e-89
CP032698.1|AYG79729.1|2064741_2066025_+|Ribonuclease-D	gnl|CDD|223426	COG0349, Rnd, Ribonuclease D [Translation, ribosomal structure and biogenesis].	2.87809e-89
CP032698.1|AYG79721.1|2055581_2056388_+|hypothetical-protein	gnl|CDD|275063	TIGR04222, integral_membrane_protein, TIGR04222 domain. The majority of the proteins with a domain as described by this model have an extreme C-terminal sequence that is consists of extremely low-complexity sequence, rich in Ser or in Gly interspersed with Cys. That C-terminal region resembles ribosomal natural product precursors, although there is no evidence that C-terminal regions of these proteins undergo any modification or have any such function.	6.35938e-21
CP032698.1|AYG79738.1|2079027_2080143_-|D-xylose-binding-periplasmic-protein	gnl|CDD|380650	cd19995, PBP1_ABC_xylose_binding-like, periplasmic xylose-like sugar-binding component of the ABC-type transport systems. Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes a transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic xylose-binding protein is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.	1.20744e-110
CP032698.1|AYG79733.1|2071408_2072920_-|hypothetical-protein	gnl|CDD|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	1.06693e-13
CP032698.1|AYG79731.1|2067799_2069932_+|Fatty-acid-oxidation-complex-subunit-alpha	gnl|CDD|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	3.90848e-109
CP032698.1|AYG79735.1|2074635_2076594_-|1-deoxy-D-xylulose-5-phosphate-synthase	gnl|CDD|183601	PRK12571, PRK12571, 1-deoxy-D-xylulose-5-phosphate synthase; Provisional.	0
CP032698.1|AYG79724.1|2058892_2060323_-|Protoporphyrinogen-oxidase	gnl|CDD|237009	PRK11883, PRK11883, protoporphyrinogen oxidase; Reviewed.	1.51345e-135
CP032698.1|AYG79734.1|2072993_2074487_-|putative-amino-acid-permease-YhdG	gnl|CDD|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	9.51966e-132
CP032698.1|AYG79720.1|2054766_2055555_+|hypothetical-protein	gnl|CDD|379301	pfam13628, DUF4142, Domain of unknown function (DUF4142). This is a bacterial family of unknown function.	3.03925e-11
CP032698.1|AYG79725.1|2060531_2061908_+|NADH-oxidase	gnl|CDD|181958	PRK09564, PRK09564, coenzyme A disulfide reductase; Reviewed.	1.32106e-125
CP032698.1|AYG79726.1|2061911_2063003_-|Uroporphyrinogen-decarboxylase	gnl|CDD|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	0
CP032698.1|AYG79728.1|2064000_2064663_+|Transcriptional-regulatory-protein-DegU	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.24614e-23
CP032698.1|AYG79730.1|2066576_2067803_+|3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA-thiolase	gnl|CDD|273881	TIGR01930, 3-ketoacyl-CoA_thiolase, acetyl-CoA acetyltransferases. This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other].	5.65217e-162
CP032698.1|AYG79723.1|2058171_2058888_-|Putative-heme-dependent-peroxidase	gnl|CDD|377705	pfam06778, Chlor_dismutase, Chlorite dismutase. This family contains chlorite dismutase enzymes of bacterial and archaeal origin. This enzyme catalyzes the disproportionation of chlorite into chloride and oxygen. Note that many family members are hypothetical proteins.	7.65617e-101
CP032698.1|AYG79736.1|2076738_2078043_-|Xylose-transport-system-permease-protein-XylH	gnl|CDD|226669	COG4214, XylH, ABC-type xylose transport system, permease component [Carbohydrate transport and metabolism].	5.79868e-83
CP032698.1|AYG79737.1|2078039_2078828_-|Xylose-import-ATP-binding-protein-XylG	gnl|CDD|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	2.43769e-101
CP032698.1|AYG79722.1|2056494_2058093_+|Tripeptidyl-aminopeptidase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	1.41819e-24

Protein sequences

>CP032698.1|AYG79729.1|2064741_2066025_+|Ribonuclease-D
MTDAHKTAAETALRTTGGAPPDDVDKAPIPLLEPREGIPPVVATDEALADVVAAFAAGTGPVAVDAERASGYRYGQRAYLVQLRREGAGSALIDPVGCPDLSGLGEVLSDTEWILHAATQDLPCLREIGMVPSRIFDTELAGRLAGFPRVGLGAMVESVLGFALEKGHSAVDWSTRPLPEPWLRYAALDVELLVDLRDALEKELDRQGKLEWAREEFDAIASAPPAPPRKDPWRRTSGMHKVRRRRQMAAVRELWTARDAVAQRRDVSPGKVLSDSAIIEASLALPAHVTALTALPGFGHRMGRRQLEQWQAAVDRAKALSEAELPQPGQPLQGPPPPRSWADKDPAAAARLSAARAAVSELAERLNMPQENLITPDTVRRVCWEPPGDRSEGAVAEALASFGARRWQIEQVTPLLSAALTATPTKP
>CP032698.1|AYG79728.1|2064000_2064663_+|Transcriptional-regulatory-protein-DegU
MSVLLEQPASLVAYRPNKPTAMVVVADPRVRSTVTRHLWALGVRDVIEASSIAEARPRVGNPRDICVADVHLPDGSGLTLLSETRAAGWPNGLALSAADDIGAVRNALAGGVKGYVVTGTRTNIGHPGRPGAAPIGAAAARMHRRPPGAPSHPGGYRELSGREVEVLRLVAEGQSNKAIGVSMGLSALTVKSHLARIARKLGTGDRAGMVAVALRTGIIH
>CP032698.1|AYG79727.1|2063069_2063723_+|hypothetical-protein
MAAAQGRTSDGADGRDAADGTSVPIPFRQAVDALRTARPRPEIELDETRPPQRLAPYAYALEAAVVEGEEDLADGRLVLLHDPAGHDAWKGTFRLVTLVRAELEPEMAADPLLPEVCWSWLTGALEARGLAYGEAGGTVTRAGSHYFGGLAERRPATQIEIRASWTPREGPGGVPDTAGHLAAWCDLLCQIAGLPPASGPADGGGGVVTLPQRRDPR
>CP032698.1|AYG79726.1|2061911_2063003_-|Uroporphyrinogen-decarboxylase
MAHAKILVVSANDRPVGQPNSTTHDSAFLKACRREAVPHTPVWFMRQAGRSLPEYLKVREGIPMLESCMRPDLVTEITLQPVRRHKVDAAIYFSDIVVPLKAIGIDLDIKPGVGPVVADPIRTRADLARLRDLTPDDVHYVTEAIGMLTGELGATPLIGFAGAPFTLASYLVEGGPSRNHENTKAMMYGDPELWADLLDRLAEITAAFLKVQIEAGASAVQLFDSWVGALAPADYRRSILPASAKVFEAVAGYGVPRIHFGVGTGELLGLMGEAGADVVGVDWRVPLDEAARRVGPGKALQGNLDPAVLFAPTAAVEAKTREVLDAAAGLEGHVFNLGHGVLPSMDPDALTRLVAYVHEQTAQ
>CP032698.1|AYG79725.1|2060531_2061908_+|NADH-oxidase
MAAERLVVIGGDAAGMSAASQARRLKSPEELEIVAFERSGFTSYSACGIPYWVAGDVPSHEELIARGPEEHRARGIDLRMRTEVTELDVAGRRVRSRDRDSGGEEWTSYDKLVIATGARPVRPALPGIDAPGVHGVHTIDDGRALLESLESAGERRAVVVGGGYIGIEMAEAMLVRGFEVTLLTRGAEPMHSLDPDMGHRLTEAMERSGITVVTDAEVTKVLTHESGRVRAVATDRAEYPADVAVLGLGVTPRTELARAAGLPLGASGALRTDASMRVRGHENIWAGGDCIEVLDLVSGRHRHIALGTHANKHGQIIGANVGGGYGTFPGVVGTAVTKVCETEVARTGLSELEAREEGLQYVTATIESTTVAGYYPGAAPMTVKMLAERESGRLLGVQIVGGAGSAKRIDIAAVALTARMTVDQMTALDLAYAPPFSSVWDPVLVAARKAVSTLRAAG
>CP032698.1|AYG79724.1|2058892_2060323_-|Protoporphyrinogen-oxidase
MDNAPARAPHIVVVGGGISGLAAAHRLLASGARVTVLEGSAVLGGKLLAGEIEGAPVDLGAESMLARRPEGVELARAVGLGDRIQAPAAAGAAIWTRGALRPMPTGHVMGVPAQPDTLHGILSAEGLARVAQDRELPPTELGEDIGVGEFVAKRVGREVVDRLVEPLLGGVYAGDAYRISMRAAVPQLFDAARTHPSLLDGVQDIQAAAAAKQRGGPVFAGLDGGIGTLPVAVADAVRAQGGEIRTETPVLALTRTADGWRIRTDSELIDADGVILSTPAWSASALLAAESPVAAAELSEVEYASMVLVTLAFRRADLAGLETRSGFLVPPVDGHTIKASTFSTHKWSWVKERGSDLFVLRTSIGRYGEERHLDWDDADLVDVSLGDLGEAVGLSAKPVASRVNRWIGGLPQYPVGHLAKVARVRAEVAKLPGLRVCGAAYDGVGIPACVASARRAADEIIATSTLARNTQSDAGQ
>CP032698.1|AYG79723.1|2058171_2058888_-|Putative-heme-dependent-peroxidase
MSAAPEKIPNAGKKAKDLNEVIRYTLWSVFKLRDVLPEDRTGYADEVQELFDQLAAKDITVRGTYDLSGLRADADIMIWWHAETSDELQSAYNLFRRTKLGRALEPVWSNMALHRPAEFNKAHIPAFLADENPRDYVSVYPFVRSYDWYLLPDEDRRRMLADHGKMARGYPDVRANTVASFSLGDYEWLLAFEADELHRIVDLMRHLRASEARMHVREEVPFYTGRRKSVADLVAGLA
>CP032698.1|AYG79722.1|2056494_2058093_+|Tripeptidyl-aminopeptidase
MRAVALYGTVGSLVLSALVAAPAGSADPLTVEARGAAAAARHAAATPIAFGRCPEVEALPPSVQCGTVKVPLDYAHPTGRQIALTVSRVKAKGKPAQRQGALVFNPGGPGASSMYFPMVADLAAWKRLAGAYDLIGYSPRGVARSAPLSCQNPADFAQAPSDAPTHPDEPYKMERIAQAQAYAAGCERNAGPALRFYTTLNNTRDLDVLRAALGEKKLTFMGSSYGTYFGAVYATLFPSHVRRMVFDSAVDPDPDQIWYRNNLDQSRAFESRWADFRTWVAKHDDVYHLGATAQEVLESYEKVRAALTRRPAGGTVGPAQLQAAFLKAGYYDDYWSSRASALAEYLKGNERPLVQQAAPRPESASDDENGNAVYTAVECNDAPWPTDFATWDRDNSELARTAPFETWDNVWMNLPCAYWPAPRQKPVDVRVQPGALPPTLILAAERDAATPYPGALELQRRLPGSVLITEKDAGTHGIAGGANACVNGYVEDYLLNGRTPVRRAECAPHREPNPVSLDERTTHRPGRAVPAL
>CP032698.1|AYG79721.1|2055581_2056388_+|hypothetical-protein
MDRLWRATVNFAYNSAMFWVLFLLPSIVAAGLSCGRLCLAAVAAARPGPRPEEERDLSCYEAAFLAGGPYRVADLTLISMHRARRLLLAHTGWATVVDPEGRDDLERSVLAAIGPGGQERIATIRSGAAAADAVRALADRLAGAGLAVPDVVRDGVSSSVRAVRGAALLITALGAAALFMPGEASIGRAEMAAWFSLPLVLTLGCLAIARMEIHPYTRWASPDGQALLGGLDAAGDPLTAVAVRGVRAVDDPQVRSALTSGRFAHRSQ
>CP032698.1|AYG79720.1|2054766_2055555_+|hypothetical-protein
MRRLLSGTGLVLVALAATLLALLFPLWSYADRSGTPLADLDAATVPTRWGPLSAADRDFVVRVRLAGLWEGPAGQQAIERGPSAAIEAAGRHLVDGHAFLDARVREVAARLGMELPDQPNDQQRGWLSQLTADTGTAYERDFANLLRAAHGKVFSLVAQVRATTRNSLVRELADDANTTVLDHMRMLEATGLVDFDALARDGASAATASPTGPPPPTPGATLASPAPLAPEASDSAEPSFSLPPAASRPKDEASSTPDTHTP
>CP032698.1|AYG79730.1|2066576_2067803_+|3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA-thiolase
MPRTVRDVVFVDGVRTPFGKAGPKGIYHETRADDLVVKAIRELLRRNPALDPAKIDEVAIAATTQIGDQGLTLGRTAGILAGLPQSVPGYSIDRMCAGALTAVTSVAGSIAFGAYDAVIAGGVEHMGRHPMGEGVDPNPRFVSEKLVDESALFMGMTAENLHDRYPQITKQRADEYAVRSQEKAAKAYADGKIQQDLVPISVRNTNAEVGETGWGLVTADEPMRPGTTLESLANLKTPFRVHGNVTAGNAAGLNDGATASIIASEEFARENNLPVKMRLVSYAFAGVEPEVMGYGPIPATEKALAKAGLSIEDINLFEINEAFAVQVLAFLDHYGIADDDARVNQYGGAIAYGHPLASSGVRLMTQLARQFEEQPEVRYGLTTMCVGFGMGATVIWENPHHKDAGGSK
>CP032698.1|AYG79731.1|2067799_2069932_+|Fatty-acid-oxidation-complex-subunit-alpha
MSTTTAELLKGAAELFPDEVVTSAHVRHLELPYGAGRFALITLDNGFDHTKPTTFGPGSLANLNAAIDQVEKEAAEGSIVGVGVTGKPFIFAVGADLKGVELLKKHEDALAIGKGGHEVFKRLAGLAVPTFAYYNGAAMGGGVEVGLHCTYRTVSKALPAFSLPEVFLGLVPGWGGCTLLPNLIGAEKAVSVIIENSLNQNRQLKGKQVFELGIADALFEGADFLEQSLIWTANVLKGDVTVERPAIDRGEAWDQAVAKGRFIADSKVHGAAPAAYRALDIIAASKDGDLQAGFDAEDSALADLIMGGELRSGIYAFNLVQKRAKRPAGAPDKNLARPVTKVGVVGAGLMASQLALLFLRRLEVPVVLTDIDQERVDKGVGYVHAEIDKLLAKSRINQDKANRLKGLVSGVLDKAEGFSDADFIIEAVFEEIGVKQQVFAEVEAVAPAHAILATNTSSLSVTEMASKLKHPERVVGFHFFNPVAILPLLEIVRGEQTDDVSLATAFGVARKLKKTAVLVKDAPAFVVNRILTRFMGEIQNVIDEGTPVAVAEKAVEPLGLPMSPLVLLELVGPAIGLHVSETLNRAFPDRFTVSENLAAVVKAGKRGFYVYDSGKPELDPEVAALLKQGDVALTEEQTRDRVLDAVAQEIGLMLDEGVVAEAQDIDLCLITGAGWPFHLGGITPYLDREGVSERVNGKKFLAQGVASVPA
>CP032698.1|AYG79732.1|2070081_2071233_-|hypothetical-protein
MALRSRQTAGGEPQRSGSIVTTPVAATPRVATEDGRPTVTGWLRLGKDGRLSAYAPATGGVARWTETRPGGAWTGPELVAPGKGLQSHLSVAQGPDGYVHLAALRQTPIEDGGTWTELVHAIQYQTGRPVKNWAVVGSPYPRRDWKLGLRMGHPSVGVDSLGNAQIVVRNAFGGVSARGQEPSGKWAGWADLNGNGADRSISVVAAEGGRMFIHAPSDDGIMRFRRAAADAKFERVDKLPGHPETATVNGLETGEDGSVTFFLRDADSGELRAWRGDGPMESLGGRGSGPVAVLRKEIDGVDCTVLAQRDRDGRPAIAAYPTEQEEAGVTWTPTGEVCVGAPALTVDADGRVVLGVFTVDGGLRITRQRTDEPGLALEAWQQV
>CP032698.1|AYG79733.1|2071408_2072920_-|hypothetical-protein
MLAEPPPSLRSATTSIPAAKGRRPTDPRAPEGYWRRLLPVLAVLALLTRLPSFRHPLWSPDEGYLAVQARLLASGGTLYTTVVDRKPPLLPWLYEAAFAVCGDGSLGPLRLAAIAAQLLTALALASTARRRWGDGAGRAAGVLYLLVSVGLNPEDAQAATFEVFMLPFTAAAVRCADRGHFTRAGLAVAGACLTKQTGGAVLLPVLWLAWHHPRPLRTSLLRTGVGLAAPVLAVALSTGPSRFLFWTVTGSAAYASFTGSELHVLARGLTNTLILAAGCAGLLPPVVRVLRIARTGAGDLWLWLIASAGAVLLGFHFFGHYYLQLIPPLVLLATGALQILPAPRLTSALSTCACACALFLVWGVLAPRPELAHSERLAAAVEARTTPTERVLVWGIHPETYWLARRAPASRYLTAGLLTNYSGGRDGPQVGEKYGVDGAWPVFRTELADRPPALVVDDSRGKPFAPDRLPTLRRFLAARYERSAVVDGAVFYVRADRPSPGRT
>CP032698.1|AYG79734.1|2072993_2074487_-|putative-amino-acid-permease-YhdG
MASKGLFRTKSIEQSIRDTEEPEHALKKSLSALDLTVFGVGVIIGTGIFVLTGKVAKENAGPGVSLAFVVAGVVCALAALCYAEFASTVPVAGSAYTFSYASLGELPAWIIGWDLVLEFALGTAVVAVGWSGYVRSLLDNAGWHLPEALSGRDGAHGFGFDILAAALVLVLTGILVLGMKLSARVTSVVVAIKVTVVLIVIIAGAFFINSDNYSPFIPKAQAQSAGGDLKAPLIQLMSGYAPTNFGVMGIFTAASVVFFAFIGFDIVATAAEETKNPQRDMPRGILGSLLICTLLYVAVSIVVTGMQHYTKLSVDAPLADAFKATGHPFFAGIISFGAAVGLTTVCMILLLGQTRVFFAMSRDGLLPRFFSHVHPRFRTPHRPTILLGVIIAIVAGFTSLSELADLVNIGTLFAFVVVAVGVVILRHTRPDLPRAFRTPLVPWVPALAVAASLWLMLNLPAETWIRFAVWMAIGVVIYFVYGRRHSRVEEPAPRTTR
>CP032698.1|AYG79735.1|2074635_2076594_-|1-deoxy-D-xylulose-5-phosphate-synthase
MLDQHGCKEARVPLLTRIRGPRDLDRLSPEQLDQLAAEIRTFLVDAVSKTGGHLGPNLGVVELTIALHRVFESPRDRVLWDTGHQSYVHKLLTGRQDFSRLKMKGGLSGYPARAESDHDVIENSHASTVLGWADGLAKANEVLGKDDHVVAVIGDGALTGGMAWEALNNIAAAKDRPLVIVVNDNERSYAPTIGGLANHLATLRTTDGYERFLAKGKDLLERTPVVGKPLYETLHGAKKGLKDFIAPQGMFEDLGLKYVGPIDGHDIEALESALQRAKRFGGPVIVHCLTEKGRGYQPALADEADRFHAVGKIHPDTGLPVSTSGLDWTSVFGEEMVALGKEREDIVAITAAMLQPVGLDKFAKAFPERVYDVGIAEQHAAVSAAGLATGGVHPVFAVYATFLNRAFDQVLMDVALHKCGVTFVLDRAGVTGTDGASHNGMWDMSILQVVPGLRIAAPRDADQVRAQLREAVAVEDAPTVVRFSKGAVGPAVQAVGRIGGMDVLREPSSAAVRPDVLLVSVGALAPMCLEIADLLDAQGISTTVVDPRWVKPVDEAMAPLAEKHRVVVTVEDNSRVGGVGSAISQALRDAGVDVPLRDFGIPPRFLDHASRGEVMTEIGLTAPDIARQVTGLVSKLDGRFEESRAAAEPVRD
>CP032698.1|AYG79736.1|2076738_2078043_-|Xylose-transport-system-permease-protein-XylH
MSTDKTSPADLGKPAAAPVDAPPPAEAASTVVDPRLLVREQGLTGYLGEFKRKVRAGDLGALPVIIGLVIICIVFQSLNSNFLTAGNLSDISVAMVGTGMIAVGIVFVLLLGEIDLSVGSVSGVAGASFAVLNIIHGTPEWLALILAILTGTVAGALHGFIFARIGVPAFAVTLAGLLFWNGFMLKILGDNGTINTNGSGVFYNLSNYFFSDVAVAYGAAAVAVAVYFLSAFFDSRRREAAGVPSRPLNEIVLRTVLLAVVAFAAAFMFNQYKGLPLAVVIFLAVLIVTDFVLRRTAYGRMIFALGGSVEASRRAGINIVLVRTSVFAISGTFAAIGGLFIASKISAANQGAGSGELLMNAIAAAVIGGTSLFGGRGRTWNALLGVLVIVSIQYGLALEGVASAIQQMITGGVLLLTVIIDAVTRKTQKSAGRA
>CP032698.1|AYG79737.1|2078039_2078828_-|Xylose-import-ATP-binding-protein-XylG
MVHVSATPVLALRGVSKRFGAVQALTDVELEVHAGEVVALVGDNGAGKSTLVKTIAGVHPIDDGVIEWEGKAVQIGKPHDAQTLGIATVYQDLALCDNIDVVGNLYLGRELKKRGVLDEVEMERRSRELLTTLSIRIPSVRIPIASLSGGQRQTVAIARSMLGEPKLVILDEPTAALGVEQTAQVLDLVERLRERGHAVVLISHNMADVKAVADKVAVLRLGRNNGVFDVKTTSQEEIISAITGATDNAVTRRAARNAEVQK
>CP032698.1|AYG79738.1|2079027_2080143_-|D-xylose-binding-periplasmic-protein
MNTNMRRAAVAVAATAMAVSLAACGSAKESGGGTKSSDGAKKGDDLKIGLLLPENQTARYEKFDKPLIEAKVKELTGGKGQIVYANAKQDATTQNQQADTMITNKVDALIVDAVDSKAIAGSVKKAKDAGIPVVAFDRLAEGPIDSYVSFDNEEVGHVQGKALLQALGDKAKSGDIVMMNGAVTDPNAKLFKKGAHAELDGKVNIGKEYDTKEWKPENANANMEGALSALGKDKVIGVYSANDGMAGGIITALKAAGLAKLPPVTGQDAELAGVQRILTGEQYMSVYKSYPQEDAIAAEMAVKLAKGESLGSLDAKKVDSPTTKGVPSTIVPVVSLTKANVNDTVIKDKIYTVAEICTGTYKAACDAAGLK
>CP032698.1|AYG79739.1|2080264_2081464_-|N-acetylglucosamine-repressor
METPGSQTSLHRANLERVVRAVRMAGSLTQAEIARTTGLSAATVSNIVRELKDGGTVEVTPTSAGGRRARSVSLSGSAGIVIGVDFGHTHLRVAVGNLAHQVLAEESEPLDVDASSAQGFGRAEELVKRLIAATGIGQDKVIGVGLGVPGPIDVESGTLGSTSILPGWTGINPSEELSGRLGVPVYVDNDANLGALGELVWGAGRGVRDLAYIKVASGVGAGLVIDGQIYRGPGGTAGEIGHITLDESGPVCRCGNRGCLETFTAARYVLPLLQSSHGADLTMERVVQMARAGDPGCRRVIADVGRHIGSGVANLCNLLNPSRVVLGGDLAEAGELVLGPIRDSVSRYAIPSAARQLSVLPGALGGRAEVLGALALVLSEMGDSTLLDSALPASAPAFT

Crispr_ID: CP032698_8

• CRISPR_ID: CP032698_8
• CRISPR_location: 2471170-2471255
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_8

Consensus_repeat	Method
GGGGCGCGAGGAACTGCGCGACCAGCCAC	CRISPRCasFinder

spacers of CP032698_8

>8.1|2471199|28|CP032698|CRISPRCasFinder
CCACGGCCCGCAGACGAAAACGGGTTTG

CRISPR arrays and Neighbor proteins around CP032698_8

CRISPR arrays

The CRISPR arrays of CP032698_8

>merge|CP032698|8|2471170-2471255|CRISPRCasFinder
GGGGCGCGAGGAACTGCGCGACCAGCCACCCACGGCCCGCAGACGAAAACGGGTTTGGGGGCGCGGGGAACTGCGCGACCAGCCAC

>CP032698|8|8|2471170-2471255|CRISPRCasFinder
GGGGCGCGAGGAACTGCGCGACCAGCCAC	CCACGGCCCGCAGACGAAAACGGGTTTG
GGGGCGCGGGGAACTGCGCGACCAGCCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80078.1|2463665_2465507_-|Translation-initiation-factor-IF-2	unknown	unknown	gnl|CDD|235401
CP032698.1|AYG80091.1|2479034_2480960_-|putative-acyl-CoA-dehydrogenase-FadE10	unknown	unknown	gnl|CDD|173850
CP032698.1|AYG80085.1|2471341_2473042_-|Proline--tRNA-ligase	unknown	unknown	gnl|CDD|236405
CP032698.1|AYG80082.1|2469123_2469669_+|hypothetical-protein	unknown	unknown	gnl|CDD|237865
CP032698.1|AYG80092.1|2483181_2484732_-|Purine-catabolism-regulatory-protein	unknown	unknown	gnl|CDD|377939
CP032698.1|AYG80089.1|2476329_2477631_-|Zinc-metalloprotease-Rip1	unknown	unknown	gnl|CDD|100084
CP032698.1|AYG80083.1|2469668_2470115_+|hypothetical-protein	unknown	unknown	gnl|CDD|373114
CP032698.1|AYG80086.1|2473133_2473697_-|hypothetical-protein	unknown	unknown	gnl|CDD|223532
CP032698.1|AYG80079.1|2466982_2467216_-|hypothetical-protein	unknown	unknown	gnl|CDD|225350
CP032698.1|AYG80088.1|2474958_2476116_-|4-hydroxy-3-methylbut-2-en-1-yl-diphosphate-synthase-(flavodoxin)	unknown	unknown	gnl|CDD|234737
CP032698.1|AYG80087.1|2473712_2474558_-|Mycothiol-acetyltransferase	unknown	unknown	gnl|CDD|379120
CP032698.1|AYG80075.1|2461813_2462719_-|tRNA-pseudouridine-synthase-B	unknown	unknown	gnl|CDD|235113
CP032698.1|AYG80081.1|2468379_2468928_-|Ribosome-maturation-factor-RimP	unknown	unknown	gnl|CDD|234627
CP032698.1|AYG80080.1|2467378_2468377_-|Transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl|CDD|237061
CP032698.1|AYG80094.1|2487460_2488795_+|4-aminobutyrate-aminotransferase	unknown	unknown	gnl|CDD|235685
CP032698.1|AYG80093.1|2484867_2487213_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80090.1|2477627_2478878_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	unknown	unknown	gnl|CDD|235472
CP032698.1|AYG80077.1|2463192_2463486_-|hypothetical-protein	unknown	unknown	gnl|CDD|377364
CP032698.1|AYG80076.1|2462721_2463159_-|Ribosome-binding-factor-A	unknown	unknown	gnl|CDD|234787
CP032698.1|AYG80084.1|2470154_2471066_+|hypothetical-protein	unknown	unknown	gnl|CDD|309685

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80078.1|2463665_2465507_-|Translation-initiation-factor-IF-2	gnl|CDD|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
CP032698.1|AYG80091.1|2479034_2480960_-|putative-acyl-CoA-dehydrogenase-FadE10	gnl|CDD|173850	cd01161, VLCAD, Very long chain acyl-CoA dehydrogenase. VLCAD is an acyl-CoA dehydrogenase (ACAD), which is found in the mitochondria of eukaryotes and in some bacteria. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. VLCAD acts as a homodimer.	1.12102e-89
CP032698.1|AYG80085.1|2471341_2473042_-|Proline--tRNA-ligase	gnl|CDD|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0
CP032698.1|AYG80082.1|2469123_2469669_+|hypothetical-protein	gnl|CDD|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	0.00229921
CP032698.1|AYG80092.1|2483181_2484732_-|Purine-catabolism-regulatory-protein	gnl|CDD|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	8.33866e-35
CP032698.1|AYG80089.1|2476329_2477631_-|Zinc-metalloprotease-Rip1	gnl|CDD|100084	cd06163, S2P-M50_PDZ_RseP-like, RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog RseP is involved in the sigmaE pathway of extracytoplasmic stress responses. Also included in this group are such homologs as Bacillus subtilis YluC, Mycobacterium tuberculosis Rv2869c S2P, and Bordetella bronchiseptica HurP. Rv2869c S2P appears to have a role in the regulation of prokaryotic lipid biosynthesis and membrane composition and YluC of Bacillus has a role in transducing membrane stress. This group includes bacterial and eukaryotic S2P/M50s homologs with either one or two PDZ domains present. PDZ domains are believed to have a regulatory role. The RseP PDZ domain is required for the inhibitory reaction that prevents cleavage of its substrate, RseA.	6.28352e-46
CP032698.1|AYG80083.1|2469668_2470115_+|hypothetical-protein	gnl|CDD|373114	pfam14530, DUF4439, Domain of unknown function (DUF4439). This domain has a ferritin-like fold.	2.15617e-28
CP032698.1|AYG80086.1|2473133_2473697_-|hypothetical-protein	gnl|CDD|223532	COG0456, RimI, Acetyltransferases [General function prediction only].	1.12069e-06
CP032698.1|AYG80079.1|2466982_2467216_-|hypothetical-protein	gnl|CDD|225350	COG2740, COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription].	4.33604e-22
CP032698.1|AYG80088.1|2474958_2476116_-|4-hydroxy-3-methylbut-2-en-1-yl-diphosphate-synthase-(flavodoxin)	gnl|CDD|234737	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.	0
CP032698.1|AYG80087.1|2473712_2474558_-|Mycothiol-acetyltransferase	gnl|CDD|379120	pfam13312, DUF4081, Domain of unknown function (DUF4081). This domain is often found N-terminal to the GNAT acetyltransferase domain, pfam00583 and FR47, pfam08445.	8.93275e-51
CP032698.1|AYG80075.1|2461813_2462719_-|tRNA-pseudouridine-synthase-B	gnl|CDD|235113	PRK03287, truB, tRNA pseudouridine synthase B; Provisional.	3.66552e-158
CP032698.1|AYG80081.1|2468379_2468928_-|Ribosome-maturation-factor-RimP	gnl|CDD|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	2.8213e-47
CP032698.1|AYG80080.1|2467378_2468377_-|Transcription-termination/antitermination-protein-NusA	gnl|CDD|237061	PRK12327, nusA, transcription elongation factor NusA; Provisional.	0
CP032698.1|AYG80094.1|2487460_2488795_+|4-aminobutyrate-aminotransferase	gnl|CDD|235685	PRK06058, PRK06058, 4-aminobutyrate--2-oxoglutarate transaminase.	0
CP032698.1|AYG80090.1|2477627_2478878_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase	gnl|CDD|235472	PRK05447, PRK05447, 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional.	0
CP032698.1|AYG80077.1|2463192_2463486_-|hypothetical-protein	gnl|CDD|377364	pfam04456, DUF503, Protein of unknown function (DUF503). Family of hypothetical bacterial proteins.	9.22581e-36
CP032698.1|AYG80076.1|2462721_2463159_-|Ribosome-binding-factor-A	gnl|CDD|234787	PRK00521, rbfA, 30S ribosome-binding factor RbfA.	5.00957e-47
CP032698.1|AYG80084.1|2470154_2471066_+|hypothetical-protein	gnl|CDD|309685	pfam04655, APH_6_hur, Aminoglycoside/hydroxyurea antibiotic resistance kinase. The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation utilising ATP. Likewise hydroxyurea is inactivated by phosphorylation of the hydroxy group in the hydroxylamine moiety.	2.05977e-51

Protein sequences

>CP032698.1|AYG80084.1|2470154_2471066_+|hypothetical-protein
MAFEPPERLVRALGETYGDALAGPWLDRLPELAEESAARRGLAVDRVQAPGGRSSLVALVRRPDGTPAALKVAPSFARPDLERAALAHWHGWGAAQLLDEETSGEAGDDALLLERLHPEVSLRSLPEAKALLEAAGTVRRLWVEPPAGHAFETVAERTERQSGPMRASRDPELAPLVSAALAARDELAAASPELLLLHGNFRQSKVLSGERAPWLTVGPEPLVGERAYDLARLVRDRVEDLIAAPSGASAARRRVNKLADSLDVDPVRLHGWTLFRAVESGLRAGVAGRHQDAELLLEFAGWL
>CP032698.1|AYG80083.1|2469668_2470115_+|hypothetical-protein
MAEPLDAAQAALAAEHAAVYGYGVLGGRLSGARAAEAHDALTAHRSRRDSLARTVRDLGGSPVAAAPAYALPFAVPDASSALRLATELEDRVAGVYSDLVRAAQGPLRQEAAAALREAAVRAVRWRGGSVAFPGLAERPSAPVPPAST
>CP032698.1|AYG80082.1|2469123_2469669_+|hypothetical-protein
MRHPGTTRRRVLAVTGAAAAGVLAGCSDAGSDSAARGSAPGAREAAARTEAALRARTSAASRALVAQYDAVLAMHPTLRDRLAPLREQAAQHGTALAPPTPAPGAPGPSSPAPSVAPSSPSAISPVPADADEALKQLARAERRTSDAQLTALATAPPELARLLASVAASGAGHAYLLGGGA
>CP032698.1|AYG80081.1|2468379_2468928_-|Ribosome-maturation-factor-RimP
MSTTQSDRLRGLLEPLVSAKDLDLEEIEVSRAGRRRVLRIVVDSDQGVELDTCAELSRAASELLDESDAMGEEEYVLEVTSPGAERPLTELRHYQRATGRLARLQLNDGDELVARILKADDEGIDTEIPGVKGRKPTARRIGFAEIAKARVEIEFNRKDGKNDIAADSENDILNDMHNEEEA
>CP032698.1|AYG80080.1|2467378_2468377_-|Transcription-termination/antitermination-protein-NusA
MDIDMSALRGLVREKEISFDLLVEAIESALLIAYHRTEGSFRRARVKLDRENGHVTVWAKEDPADLEEGQEPKEFDDTPSDFGRIAASTAKQVILQRLRDAEDDITFGEFAGREGDVITGVVQQGKDPKNVLVDIGKMEAMLPVQEQVPGEEYTHGLRLRTYVVRVAKGVRGPSVTLSRTHPNLVKKLFALEVPEIADGSVEITAIAREAGHRTKIAVRSTRSGINPKGACIGPMGSRVRSVMAELHGEKIDIVDWSDDPAEMVANALSPARVSKVEVVDLGARSARVTVPDYQLSLAIGKEGQNARLAARLTGWRIDIRPDTEQPDQSDQD
>CP032698.1|AYG80079.1|2466982_2467216_-|hypothetical-protein
MGCRERAAKSDLLRIVAVEGACAPDPRGTLPGRGAYVHPASVCLDQAVRRRAFSRAFKVGEALDTADLRTYVEQAAT
>CP032698.1|AYG80078.1|2463665_2465507_-|Translation-initiation-factor-IF-2
MQAPSVGGVMLPRGNGQSVRLSRGASLTDFAEKIGANPASLVGVMMNLGEMVTATQSVSDETLKLLADEMNFILEIVSPEEEDRELLESFDIEFGEDEGGEESLVARPPVVTVMGHVDHGKTRLLDAIRKTNVVAGEAGGITQHIGAYQVATEVNGEDRRITFIDTPGHEAFTAMRARGAKSTDIAILVVAANDGVMPQTIEALNHAKAADVPIVVAVNKIDVEGADPTKVRGQLTEFGLVAEEYGGDTMFVDISAKQGLNIESLLEAVVLTADASLDLRANPEQDAQGIAIESHLDKGRGAVATVLVQRGTLRVGDTMVVGDAYGRVRAMLDDKGENVEEAGPSTPVLVLGLTNVPGAGDNFLVVDEDRTARQIAEKRAARERNVRFARKGVRFSLENLDEALKAGLVQELNLIIKGDASGSVEALEASLLQLDVGDEVDIRVLHRGVGAVTESDINLATGSDAIVIGFNVRAAGRAAQMAEREGVDVRYYSVIYQAIEEIEAALKGMLKPEYEEVELGTAEIREIFRSSKLGNIAGVLVRSGEVKRNTKARLLRDGKVIAENLNISGLRRFKDDVTEIREGFEGGINLGNFNDIKIDDVIATYEMREKPRG
>CP032698.1|AYG80077.1|2463192_2463486_-|hypothetical-protein
MYVGTLSFDLLLGDVRSLKEKRSVVRPIVAELQRKFAVSAAEVGDQDLHRRAEIGLAVVSGETGHLTEVLDRCERLVAGRPEVELLSVRRRLHSDED
>CP032698.1|AYG80076.1|2462721_2463159_-|Ribosome-binding-factor-A
MADNARAKKLADLIREVVAEKLLRGVKDPRLGTHVTITDTRVTGDLREATVFYTVYGDDEERAAAAAGLESAKGVLRSAVGSAAGTKFTPTLTFIADALPENAKTIEDLLNKARASDAAVREVSSGAQFAGDADPYKKPGDEDDA
>CP032698.1|AYG80075.1|2461813_2462719_-|tRNA-pseudouridine-synthase-B
MSTAAKTPDGLVIVDKPSGFTSHDVVAKMRGIARTRRVGHAGTLDPMATGVLVLGVERATKLLGHLALTEKEYLGTIRLGQNTITDDAEGEIISSTDASKVTREGIDAGVAELTGAIMQVPSKVSAIKIDGKRSYARVRGGEEFEIPARPVTVSSFRVYDVREAVAEDGTAVVDLVVSVVCSSGTYIRALARDLGAGLGVGGHLTALRRTRVGPYGLDAARTLDQHQESLTVMPVAQAATAAFARWDVDARRGALLLNGVRLDMPDEYETGKAVGVFGPDGTFLALVESQKGKAKSLAVFG
>CP032698.1|AYG80085.1|2471341_2473042_-|Proline--tRNA-ligase
MAAAQVQRMSRLMAKTLRDDPADAETLSHKLLVRAGYVRRNAAGIWTWLPLGKKVLDNISTVVREEMDAIGAQEVLLPALLPKEAYEASGRWEEYGDLLFRLKDRKGGEYLLGPTHEEVFTQTVKDQCTSYKDLPVMLYQIQTKYRDEARPRSGVLRGREFQMKDSYSFDTTDEGLAESYALHRAAYQKIFARLGLDYRIVSAVSGAMGGSASEEFLAPAAAGEDTFVDCPACDYAANTEAVTFVAAPVDGSAHGPVEEIDTPDTPTIETLAAHLGVPASATLKNLLVKVDGEIVAVGVPGDREVDLGKLGEHLAPAVVELVTAEDFADRPDLVRGYVGPQGLEKVRYIADPRIAPGTAWVTGANKADTHARNVVCGRDFEVDDYLDVVVVEEGDPCPSCGAGLKLDRAIEIGHIFQLGRKYADTFQLDVLGKEGKPVRVTMGSYGIGVSRAVAALAEQTADDKGLCWPAEIAPADVHVVAAGKAVQTEAALDAAEQLRAAGLRVLVDDRAGVSPGVKFTDAELIGVPQILVAGRRVAEGVFELKDRRTGEREELPLAEAIARLSA
>CP032698.1|AYG80086.1|2473133_2473697_-|hypothetical-protein
MPDDSEVTVGPLDLAARVDEALAVQAIAFGLSAEEVGVRRHIVLRHLSYPGARALGATTADGRLAGFVYGMPNDRAHWWSTVVEPYLRNNATDHWLDDTFVITELHVHPAFQNRGVGRALITTITDTADQPRSILSAIDTESPARALYRALGYVDLARQVHFPSAARRYAVMGAPLPLLRRDPADPR
>CP032698.1|AYG80087.1|2473712_2474558_-|Mycothiol-acetyltransferase
MLMQTTTRVLEPGDLGAALAILESDPVANAFVTSRVQIAGLDPWRLGGEMWGWYADGRLRSLCYSGANLVPICATPEAVRSFADRARRTGRRCSSIVGPAEPTARLWQLLEPHWGPARDVRPHQPLMVAERMPDDIAPDPYVRRIRKDEMDVIMPACVAMFTEEVGVSPLAGDGGLLYQARVAELVGAGRSFARIEDGKVVFKAEIGAATNQACQIQGVWVAPEHRGKGLSATGMAAVLRYALADVAPIVSLYVNDFNAPARACYRRVGFRETGAFMSVLF
>CP032698.1|AYG80088.1|2474958_2476116_-|4-hydroxy-3-methylbut-2-en-1-yl-diphosphate-synthase-(flavodoxin)
MTAISLGMPSVPTRLAERRKSRQIQVGSVAVGGDAPVSVQSMTTTRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALSTIARKSQIPVIADIHFQPKYVFAAIDAGCAAVRVNPGNIKQFDDKVKEIALAAKDAGTPIRIGVNAGSLDARLLKKYGKATPEALVESALWEASLFEEHGFRDIKISVKHNDPVVMVNAYRQLAAQSDYPLHLGVTEAGPAFQGTIKSAVAFGALLAEGIGDTIRVSLSAPPAEEIKVGIQILEALNLRQRRLEIVSCPSCGRAQVDVYKLAEEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESKIVETLIDEAMKIAEQMEKDGVASGEPQVSVAG
>CP032698.1|AYG80089.1|2476329_2477631_-|Zinc-metalloprotease-Rip1
MTILLTVLGIVLFALGLLISIAWHELGHLSTAKLFGIRVPQYMVGFGPTIWSRKKGDTEYGIKAIPAGGYIRMIGMFPPGADGRIAARSTSPFRGMIEDARAAAFEELQPGDEDRLFYTRKPWKRVIVMFAGPFMNLILAVAIFLGVFMGFGTQTQTTQVEAVQKCVIAASEKRQTCEPGDAVAPAEAAGLRSGDTIVAFNGKPVKDWSDLSDRIRATIGPATVTVERQGQQITLHPTLAKNMVAKKDADGQPVPDQFVPAGYLGFLPKSVIKPLTFEQSVNHMTDAVENSVHSIAALPGKIPDLWNAAFDGGERKADSPVGVVGAARISGEVLNMDAPPENILATFMMVLAFFNLSLFLFNMLPLLPLDGGHIAGALWESLRRNVARVLKRADPGPFDVAKLMPVAYVVAGIFICFTLLVLVADVVNPVKLA
>CP032698.1|AYG80090.1|2477627_2478878_-|1-deoxy-D-xylulose-5-phosphate-reductoisomerase
MSDSPAPLADPHIAFDPTEGRRDVVVLGSTGSIGTQAIDLVLRNPDRFRVTALSAAGGRVELLAEQARRLRVRAVAVAREDAVPALREALTAQYGGEPLPEILAGPEAATELAASPCHTVLNGITGSIGLAPTLAALTAGRTLALANKESLIVGGPLVKALAKPGQIIPVDSEHAALFQALAAGKRADVRKLVVTASGGPFRGRTRGELADVTPADALAHPTWAMGPVITVNSATLVNKGLEVIEAHLLYDIPFSRIEVVVHPQSYVHSMVEFTDGSTLAQATPPDMRGPIAIGLGWPQRVPDAAPAFDWTKASTWEFFPLDNDAFPAVGLARHVGELGGTAPAVFNAANEECVDAFLAGRLPFSGIMETVTEVVTEHGTPAAGTSLTVSDVLEAETWARARARELAVKATAEAHA
>CP032698.1|AYG80091.1|2479034_2480960_-|putative-acyl-CoA-dehydrogenase-FadE10
MTAPQHKPKVSEREARQVAEAAREQDWRKPSFAKELFLGRLRLDLIHPHPQPAPEDVERGEAFLAKMRDFCETRVDGRLIERESKIPDEVVNGLKELGALGMKIDTKYGGQGLTQVYYNKALALAGSASPAIGALLSAHQSIGVPQPLKLFGTQEQKDTFLPRCARTDISAFLLTEPDVGSDPARLATAAVPDGEDTYVLDGVKLWTTNGVVADLLVVMARVPKSEGHKGGITAFVVEADSPGVTVENRNAFMGLRGIENGVTRFHRVRVPAANRIGPEGSGLKIALTTLNTGRLSLPAMCVGSGKWCLKIAREWAGAREQWGRPVARHEAVGAKISFIAATTFALEAMTDLSAQMADENRNDIRIEAALAKLYGSEMGWLITDELVQIRGGRGFETADSLAARGERAVPAEQMLRDMRINRIFEGSTEIMHLLIAREAVDAHLSVAGDLIDPDKTLQDKAKAGVGAAGFYAKWLPKLVAGPGQLPNSYGEFGPLAQHLRYAERSARKLARSTFYAMSRWQGRMETKQGFLGRIVDIGAELFAMSAACVRAEHLRAAGENGREAVQLADTFCRQSRIRVEELFTRLWSNTDDLDRKVVDEVLAGAYTWLEEGVLDPSGDGPWIADATPGPPTRDNVHRPVR
>CP032698.1|AYG80092.1|2483181_2484732_-|Purine-catabolism-regulatory-protein
MPPTLASLVQHSALKLTVRAGHEHLDRPVRWAHVSELADPVPYMEGGELLLITAMKLDAEDPQAMRRYVRRLSRAGVVGLGFAIGVTYDTVPDALLDAAREEGLPLLEVPRRTPFLAISKEVSAAISADQYRAVTAGFEAQRELTKAALFDGPAALIAKLAAHVEGWAALYDTSGAVVAAAPDWAARRAARLTADVARLRERTAPASVVVGDADEASGDRVELQSLGTGRRVRGALAVGTGAPLGTAERYAVHSAVALLTLTTERSRSLQAAEQRLGAAILRMLLSGQQDHARAVAGDLYGGLLDAPFRLVIAELAGEADPAGLGALAETMESAAARCGETVLVVPEARRLVVLAADGGEAVAACLAHAGAEGEDLVIGLSAPAGPIAAASAYKQAEQALSVARRRGKPLVEHEDLVAGSVLPLLADDAVRAFADGMLRALYEHDATGRGDLVASLRAWLSRHGQWDAAAADLGVHRHTLRYRMRRVEEILGRSLDDPDVRMELWLALKATSAPDS
>CP032698.1|AYG80093.1|2484867_2487213_-|hypothetical-protein
MDTEGTYDARGTRSGSVPRPAGPPPRPALPPRPAEGPTNGPTTLGDWLRTPRAAAEPGLWRFGHKPRPDADPERVPDRALLVGALVALLAGTLVWSLWTNGYVPHSRVLLELFTPAEWWRYPRPPEALTAIEVYNSLFAALLIYVFGRMGNWLEVFRRYAVDCPQPERTLRTALAGAVAVWLVIGTSLFPFFFTIWNLFPLSWTTGNGDRTVATFVNYGLYALVGGAVLWPFAKAGDWLGQLRKRTAAPPAQHPGAPAPVTSPADWPQLRAAGLGDAADRLVAEERSGRMNDVDCVRIRRAWATVKADPSRLGAFTEAVAAQGARACLHPSGDRDLPARAATHDLLTSQVRLGRYPDAERTPPARRGAGAALDPGSLGSSLLAIGPFGAGKTRHLVRPVVESLALQALAGKAAVVAVCAAGTPLGPDDGYDVVVKPGDASSAYDLDLYGGATDPDEAAALLAEAFAGDLAEVDPRRAATVLAQLLGPYRAAHGRFPSVTVLRELLDGSPGVLEELRARLDGEKHRAYHRELDARERQLGTPGDPGLALAARVAVLDRPAFEGFFDTTGQSRPFSLRSLEHPLRVRIDVPERGHPEAAHLLTRLILAQFTAGATARRDRSLFAFLALDDATHAVTAESVRSLQRLRNCNAGVLLTLRALGDVPEQLHTSLLGSVGCHMAFSGVTTWDGRLFAQAWGTEWVETTEVAKHTVFADQPLTRAVHALRKLVTGKAVTTDAVTVRTVERERWSASELAHQVPAGHAVLSLTTVKGEHAPPLLVDLRG
>CP032698.1|AYG80094.1|2487460_2488795_+|4-aminobutyrate-aminotransferase
MSAIPQERRVVTAIPGPKSQELQARRLAAVAAGVGSTLPVFTARAGGGIIEDVDGNRLIDFGSGIAVTSVGASAEAVVRRASAQLQDFTHTCFMVTPYEGYVAVAEQLAELTPGDHAKKSALFNSGAEAVENAVKIARAYTKRQAVVVFDHGYHGRTNLTMALTSKNMPYKNGFGPFAPEVYRVPVAYGYRWLTGPENAGAEASAQAIDMINKQIGADNVAAIIIEPVLGEGGFIEPAKGFLPAISQFAKDNGIVFVADEIQSGFCRTGQWFACEDEGIVPDLITTAKGIAGGMPLAAVTGRAEIMDSAHAGGLGGTYGGNPVACAAALGAIETMKELDLNGRAKRIEEVMKARLATMAEKYDIIGDIRGRGAMIAIELVKDRDSKTPNPEAAGALAKACHAEGLLVLTCGTYGNVLRFLPPLVIGEDLLNEGLDIIEQAFTGV

Crispr_ID: CP032698_9

• CRISPR_ID: CP032698_9
• CRISPR_location: 2513572-2513709
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_9

Consensus_repeat	Method
TTAGGGGCGCGGGGAACTGCGCGA	PILER-CR

spacers of CP032698_9

>9.1|2513596|34|CP032698|PILER-CR
CCAGCCACGCACGGTGCGAGGACGAAAACGGGTT
>9.2|2513654|32|CP032698|PILER-CR
GAAGCGACCACGATCCGCAGGTTCGGGAGGGT

CRISPR arrays and Neighbor proteins around CP032698_9

CRISPR arrays

The CRISPR arrays of CP032698_9

>merge|CP032698|9|2513572-2513709|PILER-CR
TTAGGGGCGCGGGGAACTGCGCGACCAGCCACGCACGGTGCGAGGACGAAAACGGGTTTTGGGGGCGCGAGGAACTGCGCGAGAAGCGACCACGATCCGCAGGTTCGGGAGGGTCTAGGGGCGCGGGGAACTGCGCAA

>CP032698|9|2|2513572-2513709|PILER-CR
TTAGGGGCGCGGGGAACTGCGCGA	CCAGCCACGCACGGTGCGAGGACGAAAACGGGTT
TTGGGGGCGCGAGGAACTGCGCGA	GAAGCGACCACGATCCGCAGGTTCGGGAGGGT
CTAGGGGCGCGGGGAACTGCGCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80122.1|2520022_2521156_-|hypothetical-protein	unknown	unknown	gnl|CDD|376540
CP032698.1|AYG80116.1|2512333_2513248_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80113.1|2508877_2509615_+|ABC-transporter-ATP-binding-protein-YtrE	unknown	unknown	gnl|CDD|213222
CP032698.1|AYG80108.1|2503198_2503693_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80126.1|2523264_2523651_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80117.1|2513806_2514847_-|Spermidine/putrescine-import-ATP-binding-protein-PotA	unknown	unknown	gnl|CDD|226361
CP032698.1|AYG80123.1|2521701_2521971_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80125.1|2522407_2523265_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80124.1|2521967_2522411_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80114.1|2509596_2510754_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80119.1|2516537_2517635_-|Thiamine-binding-periplasmic-protein	unknown	unknown	gnl|CDD|270263
CP032698.1|AYG80112.1|2507344_2508706_+|putative-aminotransferase	unknown	unknown	gnl|CDD|235823
CP032698.1|AYG80110.1|2505164_2506604_-|Gamma-aminobutyraldehyde-dehydrogenase	unknown	unknown	gnl|CDD|143411
CP032698.1|AYG80120.1|2517901_2519008_-|putative-dual-specificity-RNA-methyltransferase-RlmN	unknown	unknown	gnl|CDD|184689
CP032698.1|AYG80107.1|2502496_2503183_+|Glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl|CDD|176499
CP032698.1|AYG80121.1|2519262_2520039_+|Methanol-dehydrogenase-activator	unknown	unknown	gnl|CDD|239516
CP032698.1|AYG80118.1|2514846_2516562_-|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnV	unknown	unknown	gnl|CDD|224099
CP032698.1|AYG80109.1|2503788_2504982_-|Spermidine-binding-periplasmic-protein-SpuE	unknown	unknown	gnl|CDD|270308
CP032698.1|AYG80111.1|2506781_2507342_+|Regulatory-protein-AsnC	unknown	unknown	gnl|CDD|214628
CP032698.1|AYG80115.1|2511067_2512210_+|hypothetical-protein	unknown	unknown	gnl|CDD|224527

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80113.1|2508877_2509615_+|ABC-transporter-ATP-binding-protein-YtrE	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	3.77818e-63
CP032698.1|AYG80122.1|2520022_2521156_-|hypothetical-protein	gnl|CDD|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	0.0034262
CP032698.1|AYG80117.1|2513806_2514847_-|Spermidine/putrescine-import-ATP-binding-protein-PotA	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	2.49736e-117
CP032698.1|AYG80119.1|2516537_2517635_-|Thiamine-binding-periplasmic-protein	gnl|CDD|270263	cd13545, PBP2_TbpA, Substrate binding domain of thiamin transporter, a member of the type 2 periplasmic binding fold superfamily. Thiamin-binding protein TbpA is the periplasmic component of ABC-type transporter in E. coli, while the transmembrane permease and ATPase are ThiP and ThiQ, respectively. Thiamin (vitamin B1) is an essential confactor in all living systems that most prokaryotes, plants, and fungi can synthesized thiamin. However, in vertebrates, thiamine cannot be synthesized and must therefore be obtained through dietary absorption. In addition to thiamin biosynthesis, most organisms can import thiamin using specific transporters. After binding thiamine with high affinity, TbpA interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The thiamine-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	5.2141e-109
CP032698.1|AYG80112.1|2507344_2508706_+|putative-aminotransferase	gnl|CDD|235823	PRK06541, PRK06541, aspartate aminotransferase family protein.	0
CP032698.1|AYG80110.1|2505164_2506604_-|Gamma-aminobutyraldehyde-dehydrogenase	gnl|CDD|143411	cd07092, ALDH_ABALDH-YdcW, Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like. NAD+-dependent, tetrameric, gamma-aminobutyraldehyde dehydrogenase (ABALDH), YdcW of Escherichia coli K12, catalyzes the oxidation of gamma-aminobutyraldehyde to gamma-aminobutyric acid. ABALDH can also oxidize n-alkyl medium-chain aldehydes, but with a lower catalytic efficiency.	0
CP032698.1|AYG80120.1|2517901_2519008_-|putative-dual-specificity-RNA-methyltransferase-RlmN	gnl|CDD|184689	PRK14459, PRK14459, ribosomal RNA large subunit methyltransferase N; Provisional.	0
CP032698.1|AYG80107.1|2502496_2503183_+|Glycerophosphodiester-phosphodiesterase	gnl|CDD|176499	cd08556, GDPD, Glycerophosphodiester phosphodiesterase domain as found in prokaryota and eukaryota, and similar proteins. The typical glycerophosphodiester phosphodiesterase domain (GDPD) consists of a TIM barrel and a small insertion domain named the GDPD-insertion (GDPD-I) domain, which is specific for GDPD proteins. This family corresponds to both typical GDPD domain and GDPD-like domain which lacks the GDPD-I region. Members in this family mainly consist of a large family of prokaryotic and eukaryotic glycerophosphodiester phosphodiesterases (GP-GDEs, EC 3.1.4.46), and a number of uncharacterized homologs. Sphingomyelinases D (SMases D) (sphingomyelin phosphodiesterase D, EC 3.1.4.41) from spider venom, SMases D-like proteins, and phospholipase D (PLD) from several pathogenic bacteria are also included in this family. GDPD plays an essential role in glycerol metabolism and catalyzes the hydrolysis of glycerophosphodiesters to sn-glycerol-3-phosphate (G3P) and the corresponding alcohols are major sources of carbon and phosphate. Its catalytic mechanism is based on the metal ion-dependent acid-base reaction, which is similar to that of phosphoinositide-specific phospholipases C (PI-PLCs, EC 3.1.4.11). Both, GDPD related proteins and PI-PLCs, belong to the superfamily of PI-PLC-like phosphodiesterases.	2.39902e-43
CP032698.1|AYG80121.1|2519262_2520039_+|Methanol-dehydrogenase-activator	gnl|CDD|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	2.59393e-27
CP032698.1|AYG80118.1|2514846_2516562_-|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnV	gnl|CDD|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	1.88052e-91
CP032698.1|AYG80109.1|2503788_2504982_-|Spermidine-binding-periplasmic-protein-SpuE	gnl|CDD|270308	cd13590, PBP2_PotD_PotF_like, The periplasmic-binding component of ABC transporters involved in uptake of polyamines; possess the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain that functions as the primary high-affinity receptors of ABC-type polyamine transport systems. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, and plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.02445e-94
CP032698.1|AYG80111.1|2506781_2507342_+|Regulatory-protein-AsnC	gnl|CDD|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	1.46714e-32
CP032698.1|AYG80115.1|2511067_2512210_+|hypothetical-protein	gnl|CDD|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	9.21708e-12

Protein sequences

>CP032698.1|AYG80116.1|2512333_2513248_+|hypothetical-protein
MLLGLLTAIAASVCYGTGSVLQAVGSRKSARRDAAAADRTQHGGPSLSSTAKAATTWEFIVGTVLDFVGFGLGALAARLLPLFLSQTVISANLVITAVLSVKLLGIRLSRAEWTSIGVVCSALVLLASAAGHEGSGHTAPAPHWWLLAISLALIAGGTVAVRLLGARAAILAGLLSGLGFGALGVGVRILNGIDPFDAGALLCDPALYAIGVAGIGGMYLHTVALQIGSVNGATAALVVGETVLPGAIGVLWLGDASRAGLGWMAVLGFVLAVGGAVAVAWYGSEGVAEEVGATGTPTPASTPT
>CP032698.1|AYG80115.1|2511067_2512210_+|hypothetical-protein
MPDTDKTPAASDTEIETLAEFDTAVERTAQPEHAGLAGYRVQSLDLTTRTAALLTTDTAGAVFLGCAMEPDAVAKVRADGALVFPPVPHLPFDPYRGALYSPAELFEGLAAGYERTPDALSYAWFQRTSTDGDIFSSMLRSIHDDAVSDALDELLVGARVVGVMGGHAMARGTDEYRGAAVLGRTLARAGFTVATGGGPGAMEAANLGAYAAPFDDAMLDSALELLGTEPSFRPSVSRWARAAFEVRTKWPRGGTSVGIPTWFYGHEPPNAFANAIAKYFANATREDGLLARSNAGVVFLPGAAGTVQEIFDNATPNFYESRGTPTPMVLVDRAHWTETLPTWPLLQALAKDRPMAARIALVDSVSEAPEALARLSGPTG
>CP032698.1|AYG80114.1|2509596_2510754_+|hypothetical-protein
MLALRLARGTHPLVLLRRLLVSAASAGVGFLLLCTLGYAVGHPGSSVLRLLWCAVPLAATVYFAVAVARTDPSTRPRPGLSAVGLGPARLAAIAAASTAVTCTLGSAVALLVYLHLRGDLNGLPFDGAAAGLLAADQPMPVAGALTLLAVLPVTASVAAGLALRPGARRPAPASDPVHPEEPAPAPSGLPWGFALVTAGLAVETYANRGARGSAFPMPGHPEGAPAGVLGGWALTALGLALAGPALAHFSGRLLQLARPGAARLLAGRVLMAEARRIGRPLGVVSAVASGAIAAATLYGDRAGPHPFGPLTGLGAALVMSCTVATLLTATLESRHARAHTTAALLSLGTPPTVLRTATLLRALALLAVFVPLTVTIAEVAAIPLR
>CP032698.1|AYG80113.1|2508877_2509615_+|ABC-transporter-ATP-binding-protein-YtrE
MVAPPDNDVLWARSLHHSHSGSPALTGVSVGVREGEILAVGGPRGSGKTTLLRCLSGTLVPDEGEVWYNSGPVHTLGPVARERLRRDRFGWIDPEPTLVPELCAWENAALPLLLRGVAQRTAKKAALEWLERLDVDTCAKKRPHALLQAQRQRVAIARALITEPAVLFVDEPTATLHRVDRAQVLRTLLTAARSHRITTLLATHDTDVAALADRTVVLIDGRRVNSRENTGTSDAEGIAACSLSV
>CP032698.1|AYG80112.1|2507344_2508706_+|putative-aminotransferase
MSKDLSRTAYDHLWMHFTRMSSYENAPVPTIVRGEGTYIYDDKGKKYLDGLSGLFVVNAGHGRHELAETAYKQAQELAFFPVWSYAHPKAVELAERLANYAPGDLNKVFFTTGGGEAVETAWKLAKQYHKLTGNHTKYKVISRAVAYHGTPQGALSITGLPALKAPFEPLVPGAHKVPNTNIYRASIHADDPVAFGRWAADQIEQEILFEGPETVAAVFLEPVQNAGGCFPPPPGYFQRVREICDKYDVLLVSDEVICAFGRLGTMFACDKFDYVPDMITCAKGMTSGYSPIGACIISDKLAEPFYKGDNTFLHGYTFGGHPVSAAVGLANLDIFEKEGLNQHVLDNEGAFFDTLKKLHDLPIVGDVRGNGFFYGIELVKDKATKETFNDEETERVLYGFLSKALYDNGLYCRADDRGDPVVQLAPPLISDQNTFDEIEGVLRQVLTEAWTKL
>CP032698.1|AYG80111.1|2506781_2507342_+|Regulatory-protein-AsnC
MHSGFVASRSTDPRTGGGSPSRLPTTAPQGDAARRSNGTSIDAVSLAIIEQLQEDGRRPYAAIGKAVGLSEAAVRQRVQKLLDQGVMQIVAVTDPLTVGFRRQAMVGIRVEGDLDPVAEALTAMAECEYVVMTAGSFDLMVEVVCEDDDHLLEVINKRIRALPGVRSTESFVYLKLKKQTYMWGTR
>CP032698.1|AYG80110.1|2505164_2506604_-|Gamma-aminobutyraldehyde-dehydrogenase
MTTELRRLRNYIDGEFRDAADGRTIEVVNPATGQAYATSPLSGQEDVDAAMAAAAAAFPAWRDSTPAERQRVLLKIADAFEERAEELIAAESENTGKPIELTRTEEVPPMVDQIRFFAGAARLLEGRSAGEYMEGLTSIVRREPVGVCAQVAPWNYPMMMAVWKFAPALAAGNTVVLKPSDTTPASTVLIAEIIGAIVPKGVFNVVCGDRDTGRAMVEHKTPAMASITGSVRAGMQVAESASKDVKRVHLELGGKAPVVVFEDADLAKAVEDIAVAGYFNAGQDCTAATRVLVHESIHDEFVTALAKAAADTKTGQPDDADVLYGPLNNANQLKQVTGFIERLPAHAKVEAGGHRVGDQGYFYAPTVVSGLKQDDEIIQNEVFGPVITVQSFTDEAQALEYANGVEYALASSVWTKDHARAMRMSKNLDFGCVWINTHIPLVAEMPHGGFKKSGYGKDLSAYGFEDYTRIKHVMTSIEG
>CP032698.1|AYG80109.1|2503788_2504982_-|Spermidine-binding-periplasmic-protein-SpuE
MPPTAPRASTPFSRRSLLRALGGGAALTALAGCGVPAAYVAPGERAGRDRSADERSLTFANWPLYIDVDDDAGKRPTLDAFTKTTGISVTYTEEINDNDEFFGKISPALMNHQETGRDLMVISDWMAARFVRLGWVQEMDRAKQPNVTRYLDPQLRTPAFDNGRLHSVPWQSGITGIAYNRKKLGRELRHVSDLWDRSLAGKVTLFSGLDESFALLMQGNGVDITKWTADDFHRMCDQVEKQVANRQIRRFTGNDYTSDLNKGDVLACQAYSGDVFQLKADNPDIEFVVPEEGAELWAESMMIPNLAHHKANAEALIDYYYDPEVAAELAASVNYVCPVPAAREVLASSKDKDEAELAEDPLIFPDDTMRKRLAIARDITSEERTEFAKRWNAIVGL
>CP032698.1|AYG80108.1|2503198_2503693_-|hypothetical-protein
MWLVVFVVCLVLSGLTAFPLVHELRWTQSLLRHTPVGEWLPGLSGWIDRVRAGLDSADTEYPFLLYGTDWLAFAHLVIAVAFYGVARDPVRNVWVVEFGMIACAGVIPLALICGPVRGIPFWWSVIDMSFGVFGVIPLYVVRRKIKALEAMVGQWAPAAVPVPS
>CP032698.1|AYG80107.1|2502496_2503183_+|Glycerophosphodiester-phosphodiesterase
MRTVTVVAHRGDPYRVRENTLPSIASALERGADAVEIDVRTTRDGVPVLLHDETLKRLWDFDRPVSELPYAEVREVTGGGVPTLRQALMAVGAHRVLLDLPGATEEAVRAVVGTVRECGAGERVYYCAGPVNALRLRAADPGAELALNWTKPSLPRPSLVDAIKPRWLNYRFALLSSDLVAHIHRGGLLASAWTADTARTQRRLVGYGVDSITTNRLDALHKVLAGRR
>CP032698.1|AYG80117.1|2513806_2514847_-|Spermidine/putrescine-import-ATP-binding-protein-PotA
MLTLDGVTVRFGERAALDAVDLDVAEHETVCVLGPSGSGKSTLLRVVAGLQPLDGGRVLLGGADQAGVAVHRRGLGLMFQDHQLFPQRDVAGNVAFGLRMRGASRAEQADRVRELLELVGLPGAERRAVAALSGGEQQRVALARALAPSPRLLMLDEPLGQLDRTLRERLVVELRSVFAQLGTTVLAVTHDQGEAFALADRVVVMRDGRIAQSGTPLEVWQRPASEFVARFLGFENVVPATVTGEAASTPWGKVPVPPGSAQGEAHVLIRPAGVRLVPEREGLGCLVVARTFRGSHVGVRLRPGVGPVLEAECEVGAAPGVGAGVGVVFAPEGVVVLDPRPTPPLP
>CP032698.1|AYG80118.1|2514846_2516562_-|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnV
MVLARPEVERPAGKPRRGAGRRGALRGNAVRFGLLAGPLAFFAVFFAWPVAAIVGRGLKADGAWQFGRVGEVLGDPDIAHVLWFTTWQALASTALTLLIALPGAYVFARLDFPGKQLLRAVVTVPFVLPTVVVGTAFLALLGRGGLLDQLWGVRLDTTVWAILLAHVFFNYAVVVRTVGGLWSQLDPRQEEAARVLGASRLAAWRRVTLPALGPAVAAAALMVFLFTFTSFGVVQILGGPTFSTLEVEIYRQTAELLDLPTAAVLTIAQFAAVGAILAVHAWAVRRRESALSLVEPAHTSHRPRGAAQRTLLASVLAVVALLILLPVGVLVERSLDTPDGYGLGYYRALQDAGDNGSFLVPPIEAIGNSLQYALAATAIALVVGGLAAAALTRRGSGRLMRGFDALLMLPLGVSAVTVGFGFLITLDEPPLDLRTSWILVPLAQALVGTPFVVRIMLPVLRAVDGRLREAAAVLGASPLRAWREVDLPLVRRALLVAAGFAFAVSLGEFGATVFIARPDHPTLPVAVARLLGRAGDLNYGQAMALSTILMVVCAVALLVLERIRTDRSGEF
>CP032698.1|AYG80119.1|2516537_2517635_-|Thiamine-binding-periplasmic-protein
MRSTKRLAAGAIAAALGVTTLAACGGSDGKKSGSGDGSADKTVTLVSHDSFAASDPVLKAFTAQTGYTVKVLKSGDAGAALNQEILTKGSPRGDVFFGVDNTLLSRALDNGIFTPYEAKGLDRVPAEVQLDQAKHRVTPIDTGDICVNYDKKYFADKKLSPPQSFADLIKPEYKDLLVTENVATSSPGLGFLLGSVATYGDGGWQDYWKKLKSNGVKVVDGWEQAYNTDFSGSAGGKKAKGDRPLVVSYASSPPAEVIYADPKPTEAPTGVATGTCFRQTEFAGLLKGAKNEAGGKALLDFLISKKFQDDMPLNMFVDPVAKDAVLPPEFTTFGAKITHSTTVAPDTIAKNRDQWVKTWSSLVLK
>CP032698.1|AYG80120.1|2517901_2519008_-|putative-dual-specificity-RNA-methyltransferase-RlmN
MPKPGELTFVAPRGAKKPPRHLADLSPAERKEAVAAIGEKPFRAKQLSQHYFARYAHDPAEWTDIPLAARGRLQEELLPDLMSVVRHISCDEDTTRKTLWKLHDGTLVESVLMRYPDRVTMCISSQAGCGMNCPFCATGQAGLDRNLSTAEIVHQIVDGMRALRDGEVPGGPARLSNIVFMGMGEPLANYKRVVGAIRRLTDPEPDGLGLSQRGITVSTVGLVPAMHRFADEGFKCRLAVSLHAPDDELRDTLVPVNTRWKVREVLDAAWEYAEKSGRRISIEYALIRDINDQAWRGDLLGRLLKGKRVHVNLIPLNPTPGSKWTASRPEDEKAFVEAIAAHGVPVTVRDTRGQEIDGACGQLAASER
>CP032698.1|AYG80121.1|2519262_2520039_+|Methanol-dehydrogenase-activator
MGPKTQRVYETIRSWIEDGRYKAGDKLPSERSMCADLEIGRTALRQVLARLVNERLIKAYDRSSYRVLAGGDTPTPAEGEPWVIHGSRTVYDNRWVNLDLVDVEPPGVERFEHHVVRLFRVAVTAVIDEQDRVLMLWRYRFVPQQWGWELPGGIVDPGEEAAATAARETEEETGWRPGPVEHVTSYQPMIGMVDSPHEIFVARGAEKVGEPTDAEEAGEVAWIPLDDIPRLMSEGKLMGSGTLVALLHILASRTTGAR
>CP032698.1|AYG80122.1|2520022_2521156_-|hypothetical-protein
MAKGLRSARTARGWSQDRLVYEMQRFAERGLIDIASAASLKTYISEWENGRRAITDRYASILRSLLGATDAELRSEAAVRGPQVDGYADLLSRIDAASSLSESVVPSFLAQTELLRTMDRQLGASGLVDQMNGHLAAMEDALTFAVLPGARRPIAAALAGASTLAAWQALDAGAVDRAWRRYELAKKAAQDADSPMYLAHAMGEQAYVLADAGRPQLAVELVRDAQRTHAERQSPRLRAWLAAAEAELCAAAGPDMEAAARAALERANALLPDDGETRDADMLSIFLNAGHLARWRGNVLAKLGDASAMDELYASLGSADASFVRASSGLHCDLTQAHLARGELEEARSHLQQARLVANRTGSVRYRRRVEMLTGRL
>CP032698.1|AYG80123.1|2521701_2521971_+|hypothetical-protein
MKHIAALQTGVTGTLPDIEPTPAELDAIDIEMPLILAEVELLDAEIITLDRSPNELDTRRIRRARRNVLRARRALTNQSAALGTSGVGA
>CP032698.1|AYG80124.1|2521967_2522411_+|hypothetical-protein
MTANDPLNTAHAEVKAEISRTDSKVSLLLAFIGALLAGAGSVAKDIAPGVSVCAVGGLGMATLVGAAGLLLRSARPNLRGRHGFPLWATLTAEEITAAVATDRAADIAGLSRIAVAKFTALRRAVDLTMAGGALLVVALLLHVGGAA
>CP032698.1|AYG80125.1|2522407_2523265_+|hypothetical-protein
MRANPKTLLVLALVAVVGVAFRVSWNALRDVARAIGADHTAATLYPFVVDGLMALALVATLVLTGDARQFALRVLGTYTAASLVLNYVHGLIPALHQGSVDWGRLADWNAANYALVLLATSLPVGSIYFGSDLVAKVLHHQPTPTTNADESAEIVSNRSMADQGEPTPAPVVVNAAPIPRAVQVGFLKPTVPLKPLPAIQPAPVRSNSTLAADSSRPRRATGRVPDVARSARPKRTPAELLEQARSASADWPDTHLTADRLRKTVHTSAEKARGLRDALIAERAA
>CP032698.1|AYG80126.1|2523264_2523651_+|hypothetical-protein
MGTAYAKCFDPSGARYGIPTFPWKFAPDGYATRRQLRAQGLRPGGQPVAGQVMRRSRHHETGVSVAFLYRVELALPVRPMTSRKWGALALAMLARRTCPRCRVVYSYCIPRSLGMCVLCAYPADQPAA

Crispr_ID: CP032698_10

• CRISPR_ID: CP032698_10
• CRISPR_location: 2628675-2628869
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP032698_10

Consensus_repeat	Method
TTCAGGGGCGCGAGGAACTGCGC	PILER-CR

spacers of CP032698_10

>10.1|2628698|35|CP032698|PILER-CR
GACCAGCCACCTGCGGCCCGCGGACGAAGGCGGGG
>10.2|2628756|33|CP032698|PILER-CR
AAGGAGCGACCACGGCCGCAGGCCGAGAGCCGA
>10.3|2628812|35|CP032698|PILER-CR
GACCAGCCACCCGCGGCCCGCGGACGAAGGCGGGG

CRISPR arrays and Neighbor proteins around CP032698_10

CRISPR arrays

The CRISPR arrays of CP032698_10

>merge|CP032698|10|2628675-2628869|PILER-CR
TTCAGGGGCGCGAGGAACTGCGCGACCAGCCACCTGCGGCCCGCGGACGAAGGCGGGGTTGAGGGGCGCGGGGAACTGCGCAAGGAGCGACCACGGCCGCAGGCCGAGAGCCGATTCAGGGGCGCGAGGAACTGCGCGACCAGCCACCCGCGGCCCGCGGACGAAGGCGGGGTTGAGGGGCGCGGGGAACTGCGC

>CP032698|10|3|2628675-2628869|PILER-CR
TTCAGGGGCGCGAGGAACTGCGC	GACCAGCCACCTGCGGCCCGCGGACGAAGGCGGGG
TTGAGGGGCGCGGGGAACTGCGC	AAGGAGCGACCACGGCCGCAGGCCGAGAGCCGA
TTCAGGGGCGCGAGGAACTGCGC	GACCAGCCACCCGCGGCCCGCGGACGAAGGCGGGG
TTGAGGGGCGCGGGGAACTGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80221.1|2618565_2618778_-|hypothetical-protein	unknown	unknown	gnl|CDD|379386
CP032698.1|AYG80232.1|2634695_2635328_-|HTH-type-transcriptional-regulator-BetI	unknown	unknown	gnl|CDD|379409
CP032698.1|AYG80225.1|2624722_2626075_-|hypothetical-protein	unknown	unknown	gnl|CDD|370517
CP032698.1|AYG80219.1|2616957_2617788_-|putative-hydrolase	unknown	unknown	gnl|CDD|366166
CP032698.1|AYG80231.1|2633320_2634634_-|Alpha-ketoglutarate-permease	unknown	unknown	gnl|CDD|340925
CP032698.1|AYG80227.1|2627652_2628303_+|Protein-YceI	unknown	unknown	gnl|CDD|377274
CP032698.1|AYG80220.1|2617784_2618411_-|Tetracycline-repressor-protein-class-B-from-transposon-Tn10	unknown	unknown	gnl|CDD|379115
CP032698.1|AYG80237.1|2638727_2640410_-|Urease-subunit-alpha	unknown	unknown	gnl|CDD|237305
CP032698.1|AYG80224.1|2623231_2624284_+|Arabinose-metabolism-transcriptional-repressor	unknown	unknown	gnl|CDD|380483
CP032698.1|AYG80234.1|2636134_2637322_+|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG80230.1|2631375_2633019_-|(R)-citramalate-synthase	unknown	unknown	gnl|CDD|237068
CP032698.1|AYG80223.1|2620594_2622985_-|Xanthan-lyase	unknown	unknown	gnl|CDD|238517
CP032698.1|AYG80233.1|2635466_2635994_-|hypothetical-protein	unknown	unknown	gnl|CDD|376786
CP032698.1|AYG80236.1|2637680_2638718_-|Putative-agmatine-deiminase	unknown	unknown	gnl|CDD|377332
CP032698.1|AYG80226.1|2626188_2627520_+|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG80228.1|2628898_2629753_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80218.1|2615933_2616515_+|hypothetical-protein	unknown	unknown	gnl|CDD|225138
CP032698.1|AYG80235.1|2637428_2637635_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80222.1|2618790_2620374_-|Propionyl-CoA-carboxylase-beta-chain	unknown	unknown	gnl|CDD|227136
CP032698.1|AYG80229.1|2629870_2631232_-|hypothetical-protein	unknown	unknown	gnl|CDD|215598

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80221.1|2618565_2618778_-|hypothetical-protein	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	7.83984e-10
CP032698.1|AYG80232.1|2634695_2635328_-|HTH-type-transcriptional-regulator-BetI	gnl|CDD|379409	pfam13977, TetR_C_6, BetI-type transcriptional repressor, C-terminal. This family comprises the C-terminal portion of proteins that belong to the TetR family of transcriptional regulators. The C-terminus represents the regulatory region, and does not include the DNA binding helix-turn-helix domain. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. One of the target proteins is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	5.57072e-19
CP032698.1|AYG80225.1|2624722_2626075_-|hypothetical-protein	gnl|CDD|370517	pfam09471, Peptidase_M64, IgA Peptidase M64. This is a family of highly selective metallo-endopeptidases. The primary structure of the Clostridium ramosum IgA proteinase shows no significant overall similarity to any other known metallo-endopeptidase.	1.63633e-67
CP032698.1|AYG80219.1|2616957_2617788_-|putative-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	5.10489e-16
CP032698.1|AYG80231.1|2633320_2634634_-|Alpha-ketoglutarate-permease	gnl|CDD|340925	cd17367, MFS_KgtP, Alpha-ketoglutarate permease of the Major Facilitator Superfamily of transporters. This subfamily includes Escherichia coli alpha-ketoglutarate permease (KgtP) and similar proteins. KgtP is a constitutively expressed proton symporter that functions in the uptake of alpha-ketoglutarate across the boundary membrane. Also included is a putative transporter from Pseudomonas aeruginosa named dicarboxylic acid transporter PcaT. The KgtP subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0
CP032698.1|AYG80227.1|2627652_2628303_+|Protein-YceI	gnl|CDD|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	7.50294e-63
CP032698.1|AYG80220.1|2617784_2618411_-|Tetracycline-repressor-protein-class-B-from-transposon-Tn10	gnl|CDD|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	4.1113e-22
CP032698.1|AYG80237.1|2638727_2640410_-|Urease-subunit-alpha	gnl|CDD|237305	PRK13207, ureC, urease subunit alpha; Reviewed.	0
CP032698.1|AYG80224.1|2623231_2624284_+|Arabinose-metabolism-transcriptional-repressor	gnl|CDD|380483	cd01541, PBP1_AraR, ligand-binding domain of DNA transcription repressor specific for arabinose (AraR) which is a member of the LacI-GalR family of bacterial transcription regulators. Ligand-binding domain of DNA transcription repressor specific for arabinose (AraR) which is a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of AraR is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	1.10579e-55
CP032698.1|AYG80234.1|2636134_2637322_+|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.12392e-08
CP032698.1|AYG80230.1|2631375_2633019_-|(R)-citramalate-synthase	gnl|CDD|237068	PRK12344, PRK12344, putative alpha-isopropylmalate/homocitrate synthase family transferase; Provisional.	0
CP032698.1|AYG80223.1|2620594_2622985_-|Xanthan-lyase	gnl|CDD|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0
CP032698.1|AYG80233.1|2635466_2635994_-|hypothetical-protein	gnl|CDD|376786	pfam02441, Flavoprotein, Flavoprotein. This family contains diverse flavoprotein enzymes. This family includes epidermin biosynthesis protein, EpiD, which has been shown to be a flavoprotein that binds FMN. This enzyme catalyzes the removal of two reducing equivalents from the cysteine residue of the C-terminal meso-lanthionine of epidermin to form a --C==C-- double bond. This family also includes the B chain of dipicolinate synthase a small polar molecule that accumulates to high concentrations in bacterial endospores, and is thought to play a role in spore heat resistance, or the maintenance of heat resistance. dipicolinate synthase catalyzes the formation of dipicolinic acid from dihydroxydipicolinic acid. This family also includes phenyl-acrylic acid decarboxylase (EC:4.1.1.-).	1.0532e-09
CP032698.1|AYG80236.1|2637680_2638718_-|Putative-agmatine-deiminase	gnl|CDD|377332	pfam04371, PAD_porph, Porphyromonas-type peptidyl-arginine deiminase. Peptidyl-arginine deiminase (PAD) enzymes catalyze the deimination of the guanidino group from carboxy-terminal arginine residues of various peptides to produce ammonia. PAD from Porphyromonas gingivalis (PPAD) appears to be evolutionarily unrelated to mammalian PAD (pfam03068), which is a metalloenzyme. PPAD is thought to belong to the same superfamily as aminotransferase and arginine deiminase, and to form an alpha/beta propeller structure. This family has previously been named PPADH (Porphyromonas peptidyl-arginine deiminase homologs). The predicted catalytic residues in PPAD are Asp130, Asp187, His236, Asp238 and Cys351. These are absolutely conserved with the exception of Asp187 which is absent in two family members. PPAD is also able to catalyze the deimination of free L-arginine, but has primarily peptidyl-arginine specificity. It may have a FMN cofactor.	4.72888e-156
CP032698.1|AYG80226.1|2626188_2627520_+|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	8.23668e-09
CP032698.1|AYG80218.1|2615933_2616515_+|hypothetical-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	3.21215e-46
CP032698.1|AYG80222.1|2618790_2620374_-|Propionyl-CoA-carboxylase-beta-chain	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
CP032698.1|AYG80229.1|2629870_2631232_-|hypothetical-protein	gnl|CDD|215598	PLN03138, PLN03138, Protein TOC75; Provisional.	0.00473185

Protein sequences

>CP032698.1|AYG80227.1|2627652_2628303_+|Protein-YceI
MGLFGRKNSSAPAAATLDAAASPSPSAPVAPVAVDPALAALSGTYTIDPAHSSIGFVVRHAMVTNVRGSFAEHEGTLTLDGANPAASSASIDVKIASVDTGIADRDGHLRSGDFFDAEQYPLMSFRSTRAEALGGDKYRMIGDLTIKDVTRPLAIDLEFNGTATDVYGNQRVGFEGGAEILRSEWGLTWNAALETGGVMVSDKVRLTFDVSAIREG
>CP032698.1|AYG80226.1|2626188_2627520_+|hypothetical-protein
MDEPALIGRRVQQLRTQLGLTQRQLAEPAYTPAYVSTLESGKVRPSDAALRHLAERLGTTTEELATGRPARLLTELRLGLTDAQRALATGEADEAAVRYRTLLTEAELHHLDEERAEALLGLGDCALETGELTDAVRHFEASERLLAAEPLPRRARAIRGRAVAHILAGELRYACYVLESAIDELGTSGLADPEALVLLYAAIIGPYLDMGAQARAARAAELALALAPQVSDPALVAGMHRQVARTFLAEGRLADADASLAKAQSIYRQLRLRTDLAHCHWMRGYVYAQEDQLDAAERELRTARDMLAAKRAVLFTAQVEVELADVLRRLGRHAEAMTLLAPLTELGDQHGAVHAGGAHRLLGLIREERGEIEAAEEHYVTALGLLERSGASGDLADLCRLLGDLLRRAGRVEAAMDAYRTGLGHRAAPGTTTLGPAPLLPRI
>CP032698.1|AYG80225.1|2624722_2626075_-|hypothetical-protein
MRPPTRGGIATATLAGAALLATLLASPASAVTADPPPPRPKVQVEIPGPEAASGQTLAGSGPTLVPVNGRGGSAPHLSAPSSVAADGRVTKVVDNGSTADRLDIVIVGDGYTADQLDRFHADAKEKWGEITGVEPYTTYQNLFNVWTVDAVSAQSGVSGDPAQGDVKDTALGSYFWCDGVERLLCVDQDKVDSYVAKAPQADLVVVLANSAKYGGAGYNEPSPTLGYEGISTASAGNAKSGQVAIHETGHSLGKLADEYFYPGTPGYEHYEGPEADQSNISVLTADRMAAARTKWYRWLGEVSPDGGTVGAYEGGGYYVTGLNRPTDGSIMRILGKPFNLPGVEAMIAGFYRHASIATPGVSTSRTLRSYDVARVTVPRLVGERQLTVRWYLDGRELRRYAGARVVPVWGLGLGRGSHDLTVRVTDSTASVRDPGIAAGLHATVTWRAHR
>CP032698.1|AYG80224.1|2623231_2624284_+|Arabinose-metabolism-transcriptional-repressor
MHAEDRHQAILRRLRERGSLRVTDFAEELKVSAVTVRRDVEALAERGLVARVHGGALLPENAPDPTAPAVHPTGPPLVFGLVVPTADYYYPEVIKGAREAAAARGIRLVLGISQYRPDEERAQVRQLLAHGIDGLLIAPCGPVGDQDWLTALGVPFTLVERRSGDDVPGAERVVTDHAYGARLAVRHLAESGRERIGLLLRADSPHGALVQEGYLGGLASLGRPAPESLRFTLTAPETDPVRRDAQLDAFTRAVGGGLLDAVLVHNDHDAIVLLPRLRARGLSVPGDLAIVAYDDEVAALADIPLTAVAPPKRAVGVAAVDMLSQRIAAPARPHHHLAILPTLTLRASST
>CP032698.1|AYG80223.1|2620594_2622985_-|Xanthan-lyase
MPSPQGSSRRTFLAASGTGAAAVSLGLALPAARAGASQLALDGDEFDTLRLRWRDLTLGTGFDAKAEPYATKLAALGTAARTALATMAPATGSLWPDQPLTVPATGSANMSASYGRLSTMAQAWAQPGTGSTGDTALIAAVGRGLDHLHAQIYNESTKPFGNWWDWQIGSPRLLLDTAVIAYETLTAEQIAHYAAAVDHFVPDSAVAVYAGTSTGANRTDLCRVLATRGVLGKTAAKIALARDALSPVFPYVTTGDGLYADGSFIQHTWIAYTGSYGEVQIDGLSRLFALLAGSTWAVTDPNRQIILDSVERSYAPFIHDGLMMDCVNGRAISRQATDDQLMGRTIMAHIAMLALGASAAERDRWRSLIKGWVDRAPSVPVLADQRLSVANLALLRAAVDAAPSAAPAPTGPRLFPAMDRAVHRGTRFAASLSMSSHRIAYYENGNGENLRGWHTGSGMLAWWGEGFAGDQYSDAFWPTADPYRMPGTTVARKPLADGEGGAWGAARPATTWVGGAEDGTYAVVGQHLKGLSSTLTARTSWFFVGNEIVCLGAGITASDGAPVESVVDHRNLGAAGTNALTVDGRRLPATLGRHDTFRRARWAHITGHGGYVFPDGAAVQALREERTGTWRAINTGGTADPVTRRYLTLWCDHGTDPTDASYAYVLLPGARQLETAVRAADRDKVRVLANSASVQAISAHRLGLLAANFWTAGAIGGLAVDGPASVLVHTAHRMATLSLAAPERTGAPVELVWDRPVRSVATRDPRVEVLATGGSLRLRIAPGTTCGTVRTNVVLR
>CP032698.1|AYG80222.1|2618790_2620374_-|Propionyl-CoA-carboxylase-beta-chain
MTVVDQTPGEPSDTRGRVAELLALREEARRGPSERATEAQHAKGKLTARERIDLLLDPDSFHEVEQLRRHRAVGFGLEAKKPYTDGVITGWGTVEGRTVFVYAHDFRIFGGALGEAHATKIHKIMDMAIAAGAPLVSLNDGAGARIQEGVSALAGYGGIFQRNTRASGVIPQISVMLGPCAGGAAYSPALTDFVFMVRETSQMFITGPDVVRAVTGEEITQNGLGGADVHAETSGVAHFAYDDEETCLAEVRYLISMLPSNNRENPPVHPSDDPADRRSEVLLDLVPADGNRPYDMHKVIEELVDDGDFLEVHERWARNIICALARFDGQVVGIVANQPQSLAGVLDIEASEKAARFVQMCDAFNIPIVTLLDVPGFLPGVSQEHGGIIRHGAKLLYAYCNATVPRISLILRKAYGGAYIVMDSQSIGADLTYAWPTNEIAVMGAEGAANVIFRRQIAEAEDPEAMRTRMVKEYKAELMHPYYAAERGLVDDVIDPAETRAVLIASLAMLKTKHADLPSRKHGNPPQ
>CP032698.1|AYG80221.1|2618565_2618778_-|hypothetical-protein
MTTSNPNSSESLLRVEKGDAAPEELAAITAVLLARAAAQPAAAPKRGRSTAGWRRLERTPGFRAPHSWQG
>CP032698.1|AYG80220.1|2617784_2618411_-|Tetracycline-repressor-protein-class-B-from-transposon-Tn10
MVRVGLTAERLAAAGAELADDVGFEGLTVSALARRFGVKDASLYSHIKNLRELRQRVTLYAASEFIDSIAAAVAGRAGKDALVAFADAYRAYALAHPGRYAATQHQVDPELLAGSTVMARTADTTYGMLRAYGLTEPDLTDAVRLLRSTFHGYISLEAEGGFGHPREVQRSWERGVQALHILLEHWPRDQDQEKAQEKDQEKEGGEER
>CP032698.1|AYG80219.1|2616957_2617788_-|putative-hydrolase
MTEPTIGTLKVPGATLRYEVRGTGPVLLLIPGGGGDAGIFEPVADALADRFTVVTYDPRGHSRSPLDGPDVDQRVETQAEDAHRLLDRVAPDGSPAYVFGTSSGAIVAVELLIRHPERIARVVAHEPVLVSLLPDAAEHHAFFSHVVATFREAGVDAAMAEMSAGCGEERGEKPDLSGLSPRMLTTFERVRGNSAFFLGRVLGPFSAHEPDLAQLDACGGKLVPAVGWASYGLRLWRPAAWLGERYGVALAEFAGGHVGVVTHPAPFAGTLAALLR
>CP032698.1|AYG80218.1|2615933_2616515_+|hypothetical-protein
MDFASSSGGAARSTTSAKIVVAGGFGVGKTTFVGAVSEINPLRTEAVMTSASAGIDDLTHTGDKTTTTVAMDFGRITLDQDLILYLFGTPGQDRFWFMWDDLVRGAIGAVVLVDTRRLADCFPAVDYFENSGLPFVIALNGFDGHQPYTPDEVREALQIGPDTPIIVTDARHRADAKSALITLVEHALMARLR
>CP032698.1|AYG80228.1|2628898_2629753_-|hypothetical-protein
MAACADAEALLRAGRTSAARKAARAALYTDGPDPCLYALLGRAHAAEGDADHADRAETVFREGLAAFPDDLGLLTAYTALCRSAPDPARTDRAAELAARLGELGANGAQGRPSASRVQRHDARLVLTVIGHPAGAAHRAWDRARTTPDDDRTAILAETLTALARPGRAPLRLLVRAPLTGVVVCWSWFVTTLLAVTALHLPAWTSLTALLGPALFPLLYGVLRGARGRAARRAPATPAVATGDAAFPALPEVPPYTAREKVTVGVVLVAVAVTLGVLVVRLPGG
>CP032698.1|AYG80229.1|2629870_2631232_-|hypothetical-protein
MRLRVFSALSAVALAALATAGPAMAATGASDVAEHLKKSPVYVDPGAANQLSAAQADALAKKIKDADKPLFVAVLPNSAAFPKDSILGYLRTDTGVTGLYAIRLGDAFTSGADHKVMPKQAVQNLNSAVRAPGTGDDAATQLNAFVDKALPQMKGHAPASWGGGSASDDGAGAGALIGVGAVVVAGGAGAYALVRRNRKKKAEQGRAALQRLQVVVDEDITAFGEELDRLDFHPAEAGADDAMRADYERALDAYETAKSLMAKAERPADVTGVTQALEDGRFSLATLAARREHRPLPERRAPCFFDPRHGPSVEDATWTPAGGAPRQVPVCQADATRLRDGQDPMVREVDTDQGRRPYYDAGPAYGPWAGGYFGGGMLPGLLMGTMLGSMLSTPAYASDYGAGAYGPGSFDAGSGFDGGDVSGSNFDPSDFGGGWGDGGGGGGDGGGFGGGDW
>CP032698.1|AYG80230.1|2631375_2633019_-|(R)-citramalate-synthase
MTTNEANEPAEESLLDGPRVDDSFHVFDTTLRDGAQREGINLTVADKLTIARHLDEFGVGFIEGGWPGANPRDTEFFARARQEITFHNAQLVAFGATRRAGGKAAEDPQVRALVESGAPVITLVAKSHDRHVELALRTTLDENLEMIRDTVSYLREQGRRVFLDCEHFFDGYKANPEYAKAVVRAASDAGADVVILCDTNGGMLPAQIQAVVATVLADTGARLGIHAQDDTGCAVANTLAAVDAGATHVQCTANGYGERVGNANLFPVVAALELKYGKRVLPQGALAEMTRISHAIAEVVNLAPSTHQPYVGVSAFAHKAGLHASAIKVDPDLYQHIDPGLVGNHIRMLVSDMAGRASIELKGQELGIDLGDDREVVARVVERVKERELRGYTYEAADASFELLLRDEVEGGPRDYFRIESYRAIIETLKDGTHANGATVKFWVGEERIIVSAEGNGPVNALDSALLEGLERFYPQVAKFELVDYKVRTLEGKHGTASTTRVLITTTDGTGEWTTVGAGPNVIEASWEALQDAYTYGLLRAGTQPRR
>CP032698.1|AYG80231.1|2633320_2634634_-|Alpha-ketoglutarate-permease
MGREHWKKIWVGSAGNMVEWFDWFVYATFAVYFADAFFPKGNETANLMNTMGIFAVGFFMRPVGGWLLGRIGDRKGRKAALTMTVTLMSASAVLIAIAPTYAVAGYGGVAVLLVARLLQGLSVGGEYAASATYLTEASDPGKRGFASSFQYVSMTAGQLVGLGLQIVMQRNLSDAALHSWGWRIPFIVGALGAGIVFYLRRSMLETEVYAESGAAHDEDRGTLKALWAHRREAFLVMALTMGGTVAYYTYTTYLTKFLSKSAGMEKSTASLVSFCALFVFMCLQPLAGALSDRIGRRPLLITFAIGSTFLTVPIMTMLKHAGTFWPAFGLALLALVVVTGYTSINACVKAELFPTGIRALGVALPYALANALFGGTAEYVALWFKKAGIESGFYWYVAGCAAVSLVVYLTMRETRDIDLNRTENAPRRTQAEPVPSN
>CP032698.1|AYG80232.1|2634695_2635328_-|HTH-type-transcriptional-regulator-BetI
MNAPRRRNTAPPREELLAAAMATIAERGLDGLTMAGLGREVGMSSGHLLYYFRTKDELLLQTLEWSEGRLGEERRGLLVRPGTARERLDAYVDLYVPDGPRDPHWILWLEVWNRSQNADAGARARQAAIEGAWHRDLVAIIAEGVSRGEFRPVDADRFAARLRALLDGFSVHVAVGLPGTGRPQVLDHVREFVDQDLMRQTRRGEHNVRK
>CP032698.1|AYG80233.1|2635466_2635994_-|hypothetical-protein
MFCSAAPPVFEVATVIEALQARGWDVCLGLTPTAASWLDDSLSGLATLTGHPVRSQYKRPEEPDVWPPADAILFAPATFNSVNSWALGLTSNFVVGVVAEGVGKRIPMVAMPCVNAAFVQHPQFEQSVAVLRESGVTVLYGEGGFVPNQPGERRPEGYPWRIALDAVEAVAGAPR
>CP032698.1|AYG80234.1|2636134_2637322_+|hypothetical-protein
MARSDDHTGARIKEQRKLARLTQRQLADRIPYSYSLLNQVECGAKPATIDLIAAVAHALRIDVTVLTGQPYVTELQQDRLAVLVRPIREALDLYDLGADDTIEARPVALLVTAADQLCAEVRATRLRSAAMQLPTLIAELTSAVWRSPCTELWRALASTYRTAHDITVKLGYYDLSSVALDRLGWAAHRASDPCLDGLRQYMRALVYFREGDYGVGQRLISSGHGILTAADISRESIAVTGQLHLGASVIAARAHDSHAVETHLSEAAGHARRIGDASDVHWLSFGPTNVALHRMSAAVEMHRYDDALAQAKKLKPQLPSALATSRRAHFLVDRARSEMETGRAEAALSSIIEARRTAPEQTRYHPGARETIKGLVHLSRRTPDSLGHMAAWIGL
>CP032698.1|AYG80235.1|2637428_2637635_+|hypothetical-protein
MTDSTSATRVCFYCPKPGADCCIRLAAAMPGRAPVPVYAHAACAAAHGIKPLYFETGTPHTVVAFPWA
>CP032698.1|AYG80236.1|2637680_2638718_-|Putative-agmatine-deiminase
MSAAADGFRMPAEWAPHERTWMAWPGPNVTFPNDAELAQSRAAWASVARAVRRFEPVTMVVGPGQSEGARALLGPDIDLVERELDDAWMRDIGPTFLTDGKGQLAAVDWTFNGWGAQDWATWEHDAKIGAHVSDLAGARTYTSRLVNEGGAIHVDGEGTVLLTETVQLGPERNPHWTREEVETEIHAMLGTRKAIWLRRGLTADYPPHGYGTLGHVDIVAAFARPGVVVAHTQPDPSHPDHELCKENVALLRSQTDARGRRLEVVEIPAPTVVQDDHGWVDYSYINHYLCNGGVVLCAFDDPRDENAAGIFRRLFPDRTVTLVDARTIFAGGGGIHCITQQQPRV
>CP032698.1|AYG80237.1|2638727_2640410_-|Urease-subunit-alpha
MDPYEYASVHGPRTGDRIRLGDSGLTVRVESDAQRPGDEFLAGFGKTARDGLHLKAAAVRDTCDVVISNVVVIDAVQGIRKVSIGIREGRICSIGRAGNPDTLDGVDVVVGTGTSIVSGEGLIATAGAVDTHVHLLSPRIMEASLASGVTTIIGQEFGPVWGVGVNSPWALRGAFAAFDAWPVNIGFLGRGSSSDGAPLVEALAEGGACGFKVHEDMGAHTRALDTALRVAEDHDVQVALHSDGLNECLTVEDTLKVLEGRTIHAFHIEGCGGGHVPNVLKMAGVPNVIGSSTNPTLPFGRDAVAEHYGMIVSVHDLKTDLPGDAAMARDRIRAGTMGAEDVLHDLGAIGITSSDAQGMGRAGETVRRTFAMAGKMKAELGPLEGDGSDDDNARVLRYMAKLTINPAIAHGLSHEIGSIEVGKMADIVLWRPAYFGAKPQMVLKSGFPAWGVTGDPNAATDTCEPLVLGPLFGAHGGTAAELSVAFVAKAALDQGADQLPTRRRRVAVRGTRGIGPADLLLNSRTGAVGVDGRTGLVTLDGDPLRSEPADSVSLNRLYFL

Crispr_ID: CP032698_11

• CRISPR_ID: CP032698_11
• CRISPR_location: 2799302-2799388
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_11

Consensus_repeat	Method
GGCTGGTCGCGCAGTTCCCCGCGCCCC	CRISPRCasFinder

spacers of CP032698_11

>11.1|2799329|33|CP032698|CRISPRCasFinder
CAAAACCCGTTTTCGCCTGCGGGCCGTGTGTGT

CRISPR arrays and Neighbor proteins around CP032698_11

CRISPR arrays

The CRISPR arrays of CP032698_11

>merge|CP032698|11|2799302-2799388|CRISPRCasFinder
GGCTGGTCGCGCAGTTCCCCGCGCCCCCAAAACCCGTTTTCGCCTGCGGGCCGTGTGTGTGGCTGGTCGCGCAGTTCCCCGCGCCCC

>CP032698|11|9|2799302-2799388|CRISPRCasFinder
GGCTGGTCGCGCAGTTCCCCGCGCCCC	CAAAACCCGTTTTCGCCTGCGGGCCGTGTGTGT
GGCTGGTCGCGCAGTTCCCCGCGCCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80364.1|2800981_2803066_+|Phosphate-acetyltransferase	unknown	unknown	gnl|CDD|235537
CP032698.1|AYG80367.1|2806057_2807302_+|D-alanyl-D-alanine-carboxypeptidase-DacF	unknown	unknown	gnl|CDD|224600
CP032698.1|AYG80363.1|2799700_2800726_-|ATP-dependent-6-phosphofructokinase-2	unknown	unknown	gnl|CDD|235111
CP032698.1|AYG80370.1|2810338_2810842_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80354.1|2792350_2793037_+|Transcriptional-regulatory-protein-DpiA	unknown	unknown	gnl|CDD|226931
CP032698.1|AYG80353.1|2790755_2792354_+|Sensor-histidine-kinase-DcuS	unknown	unknown	gnl|CDD|225827
CP032698.1|AYG80368.1|2807321_2808803_-|hypothetical-protein	unknown	unknown	gnl|CDD|240081
CP032698.1|AYG80355.1|2793149_2794520_+|Cyclodextrin-binding-protein	unknown	unknown	gnl|CDD|270453
CP032698.1|AYG80357.1|2795409_2796258_+|Trehalose-transport-system-permease-protein-SugB	unknown	unknown	gnl|CDD|223472
CP032698.1|AYG80372.1|2812284_2813253_-|Thioredoxin	unknown	unknown	gnl|CDD|225660
CP032698.1|AYG80362.1|2798641_2799250_+|hypothetical-protein	unknown	unknown	gnl|CDD|197775
CP032698.1|AYG80358.1|2796289_2796736_-|Mycothiol-acetyltransferase	unknown	unknown	gnl|CDD|366181
CP032698.1|AYG80356.1|2794516_2795413_+|Trehalose-transport-system-permease-protein-SugA	unknown	unknown	gnl|CDD|224096
CP032698.1|AYG80366.1|2804398_2805829_+|Pyruvate-kinase	unknown	unknown	gnl|CDD|180487
CP032698.1|AYG80365.1|2803062_2804292_+|Acetate-kinase	unknown	unknown	gnl|CDD|234680
CP032698.1|AYG80371.1|2810940_2811642_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80361.1|2798210_2798438_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80360.1|2798040_2798214_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80359.1|2796698_2797910_-|hypothetical-protein	unknown	unknown	gnl|CDD|197775
CP032698.1|AYG80369.1|2808975_2810349_-|hypothetical-protein	unknown	unknown	gnl|CDD|223021

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80364.1|2800981_2803066_+|Phosphate-acetyltransferase	gnl|CDD|235537	PRK05632, PRK05632, phosphate acetyltransferase; Reviewed.	0
CP032698.1|AYG80367.1|2806057_2807302_+|D-alanyl-D-alanine-carboxypeptidase-DacF	gnl|CDD|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	7.37773e-50
CP032698.1|AYG80363.1|2799700_2800726_-|ATP-dependent-6-phosphofructokinase-2	gnl|CDD|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	1.74074e-177
CP032698.1|AYG80354.1|2792350_2793037_+|Transcriptional-regulatory-protein-DpiA	gnl|CDD|226931	COG4565, CitB, Response regulator of citrate/malate metabolism [Transcription / Signal transduction mechanisms].	1.4563e-65
CP032698.1|AYG80353.1|2790755_2792354_+|Sensor-histidine-kinase-DcuS	gnl|CDD|225827	COG3290, CitA, Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms].	1.1573e-117
CP032698.1|AYG80368.1|2807321_2808803_-|hypothetical-protein	gnl|CDD|240081	cd04730, NPD_like, 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase family that reduce a range of alternative electron acceptors. Most use FAD/FMN as a cofactor and NAD(P)H as electron donor. Some contain 4Fe-4S cluster to transfer electron from FAD to FMN.	4.26031e-15
CP032698.1|AYG80355.1|2793149_2794520_+|Cyclodextrin-binding-protein	gnl|CDD|270453	cd14750, PBP2_TMBP, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose; possesses type 2 periplasmic binding fold. This group represents the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.07815e-88
CP032698.1|AYG80357.1|2795409_2796258_+|Trehalose-transport-system-permease-protein-SugB	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.2892e-64
CP032698.1|AYG80372.1|2812284_2813253_-|Thioredoxin	gnl|CDD|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	7.0064e-59
CP032698.1|AYG80362.1|2798641_2799250_+|hypothetical-protein	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	3.95672e-05
CP032698.1|AYG80358.1|2796289_2796736_-|Mycothiol-acetyltransferase	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.84477e-15
CP032698.1|AYG80356.1|2794516_2795413_+|Trehalose-transport-system-permease-protein-SugA	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	1.84539e-68
CP032698.1|AYG80366.1|2804398_2805829_+|Pyruvate-kinase	gnl|CDD|180487	PRK06247, PRK06247, pyruvate kinase; Provisional.	0
CP032698.1|AYG80365.1|2803062_2804292_+|Acetate-kinase	gnl|CDD|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
CP032698.1|AYG80359.1|2796698_2797910_-|hypothetical-protein	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	0.00288612
CP032698.1|AYG80369.1|2808975_2810349_-|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	7.82375e-07

Protein sequences

>CP032698.1|AYG80362.1|2798641_2799250_+|hypothetical-protein
MAPGHVAYGMRAQYGLLVSPDTVTAWERGLAAPEARELTALAGVLWCSPGDLMAAASTLREHRLARGLGIEDMARRVGLDAGAYRRMEDAGRWRGNERQSAALADLLQLPLRDYVTATGQNEDLAELLRGAVTTRWQAYVKPTAKLLPLSRQHLEGVLDQLHTEYQSHMVATLNWGAANDTGDAGRDFLDRIVERFWELAHG
>CP032698.1|AYG80361.1|2798210_2798438_+|hypothetical-protein
MTAGRDIKICLYCDRPIEGVAIPVSGESHLGSASGARADDWRHVKGDRACRAAPLVERFDRAEPRGRFLEGRPQR
>CP032698.1|AYG80360.1|2798040_2798214_+|hypothetical-protein
MTVQPAGVQACCHDGVLTDEPIKVGEVHTPAGVGAEVFSCPQHLPLYRAQDEMGPAS
>CP032698.1|AYG80359.1|2796698_2797910_-|hypothetical-protein
MKETFGQALRRLRGPRSLRDVAAIAACGKSYIADLEKGQRFPSKEIAAALDQAVGAHGELIALADTRPGADPLEQADALQRGLHETLTAGPLSHYSLDEVEYTVARHGRATRYRAEGELLPELLADFGDLRLMLSGRQTVQVRKRLTIAVARMSGLMALTLLKLGDGRSRGWWRTGRAAAAAAEDRATLSWMYAQKAYQLYYGGDLEGAVELACRAQQLAGGLPCVGPALAAPLQARALALLGRRGEAIAALAEAEAALDRLAPADTAASAFGYSESQLRFHSGNAWTHLGETSVAAEQQERALELYPASDHMDRALVRLDQAMCQAADGDAAEAAAHATQTLMDLPTEHRSALIVYRAAELVARVPEARTVPEVRVLREALALPPGERATSGADQPSDRARP
>CP032698.1|AYG80358.1|2796289_2796736_-|Mycothiol-acetyltransferase
MVRISPATEHDLEAIADILGETEAYYGGENDRPPLDQIRSALFGESPAAVCLLAHDGDQVLGLASYSLLWPAAGADSSLYLKELYVREGARRRGVARALMDAVKSAAVKAGCSRVEWTADTDNPPALALYEALGVPQHQGKVFYRVSL
>CP032698.1|AYG80357.1|2795409_2796258_+|Trehalose-transport-system-permease-protein-SugB
MRAVPARRTRRHKRRRLAADAALLVVAAAFAVPLLWLLLASLDSEADLRVRVPGSATLDNFSAVLTPDITYTPMLNSLLLCGSSTLLTVVCAALAAYPLSRHRSRLARPYLLTVLFTTCLPITAVMVPVYGLFVRVDLVDTTYGTALFLATSQLPFAIWLMKNFMDGVPLALEEAAWTDGASMPQTLVRVVLPLMGPGVAVVTIYTFIMLWGNFFVPFMLLLTPDKLPASVSILTFFGNHGSVVYGELAAFSILYSTPVLLLYVLIARRLGGGFAAAGGVKG
>CP032698.1|AYG80356.1|2794516_2795413_+|Trehalose-transport-system-permease-protein-SugA
MSPAPSAPATTGLRRARAVRWLPIAPATLLLLLFLAGPIGYCGYLAFTDMRLTGSATVDFVGFANFRRAFADPAFRNAVVLTLVFTVLSALLGQNTLGLALAALMRRASRPVRTVTGALVITAWVLPEIVAAFLLYAFFRREGTLNALLDQLHLPTQNWLFTLPILAVSFANVWRGTAFSMLIYSAALAEIPRDVEEAAEVDGASGARRFWHITLPMIRRSIGTNLMLNTLQTLSVFGLIWAMTRGGPGNRSQTLPVYMYDQAFLKSLIGYGTAVALLLLLVGSLFSVVYLRLLKVEV
>CP032698.1|AYG80355.1|2793149_2794520_+|Cyclodextrin-binding-protein
MRPTAPAPRPRPIRHGRRCSLILAASLVAGALAGCGGSGGDADTVKIAYNRSTDNNIRFKDAFLEAVRKQFEQAHPGKKVELVPIQAADNDYAAKVQQMMRSPKTAPDLVYEDTFRISSDIAAGYLRPLDDQLSRWDLWGQFVDTAKAAARAEDGRTYGVPDGTDTRGLWFNKEIFAKAGLPANWQPRTWAELLDAARSVRRKVPGVIPLNVYTGKAAGEAAAMQGFEMLLYGTGADPLYDPAAKKWATGSRGFRDALDFVRTVYTEKLGPDPSDALDPNVGTRLATDWMPNGKLAIALDGSWLGQNWIHKGPKEWPAWSTALGQAAMPTQYSQPPGKVSLSGGWTWAIPAKAAHPDLAFDFVKTLQTKENAVKWDVADAQIAVRQDVAADPAYLRSMPGITFFTGLVPFTHYRPALPAYPQVSAAIGEAMESVTTGGSTASAARAYDDQLASLTR
>CP032698.1|AYG80354.1|2792350_2793037_+|Transcriptional-regulatory-protein-DpiA
MIRVLVVEDDSVAAEAHHLYVGRVPGFTAVAVAHSRAEALRALERTEVDLLLLDLYLPDGHGLQLVRSLRAAGHGADVVAVTSARDLTMVREGVSLGVVQYVLKPFTFPTLRDRLVRYAEFRAAAGEASGQEEVDRALAALRAPQPSALPKGLSAPTLQAVTRTLRERPGGVTAAEAGLAVGISRITARRYLEHLVASGRAERTPQYGQIGRPELQYRWLNSPPSHGS
>CP032698.1|AYG80353.1|2790755_2792354_+|Sensor-histidine-kinase-DcuS
MRLPGPRSLAGQLFAMQVVLVAAIVAGCALFSYLTDRGQAEETARRQAVATATSVAASPAVIAAARTADPTAALQPYTETLRTTTGVDFVVVMAPDGTRWTHPVPGEIGRAYLGDIAPALRGRTFTETHMGVLGPSVRVVAPVRDPDDHGRITALVSAGITIDRISEQVHKQLMALAAMAAGALALGGLGTYVINARLRRHTHGMNAAELSRMHDYHQATLHAVREGLLMLDGQRRIALINDGGRELLGLGEDAVGRPVAELGLPTALAGALLASEPRVDEVHMTADRIVVLNSRPVSSGGRRGTVVTLRDHTELQALSSELDSERGFTQALRAQAHEAANRLHTVVSLIELGRVEDAVEFATAELELAQALTDQVVTAVGEPVLAALLLGKAAQANEHGVELVLTEGSAVGDGLLADALPARDLVTILGNLLDNAVDAAQGSAVAEVAVTLTTEDGSLVVRVADSGPGVDPAAAEAVFERGWSTKSPGRGLGLALVRLTAARHKGTIALTQSPYGGAEFTVRLPIEQGVRA
>CP032698.1|AYG80363.1|2799700_2800726_-|ATP-dependent-6-phosphofructokinase-2
MRIGVLTAGGDCPGLNAVIRSVVHRAVVGHGDEVIGFEDGFKGLLDGHFRPLDLNAVSGILARGGTILGSARLERDRLREASENCAELAKRYGIDALIPIGGEGTLTAARMLSEAGMPVVGVPKTIDNDISATDRTFGFDTAVGVATDAIDRLKTTAESHQRVMVVEVMGRHAGWIALESGMAGGAHGICLPERPFQVDDLVKMVEERFSRGKKFAVICVAEGAHPAEGSMPYERGAIDQYGHERFAGIGNRLAVELERRLGKEARPVILGHVQRGGVPTAYDRVLATRFGWHAVEAVHRGAFGNMTALRGTDIVMAPLADAVTSLKTVPDARMYEAESVF
>CP032698.1|AYG80364.1|2800981_2803066_+|Phosphate-acetyltransferase
MTRSVYVTGIDRGDGRQVIELGVMELLTRQVDRVGVFRPLVHDGPDRLFDLLRARYRLAQDAATVYGMDYHEASALQAEKGTDELVSLLVERFHQVARDYEVVLVLGTDFADTQLPDELALNARLANEFGASVIPVVGGKGQTAESVRAEARNAHRAYDGLGCDVLAMVVNRVAPADRQEIEERMRTRLPVPCYVLPDEPALSAPTVAQITAALGGTVLLGDDAGLARDALDFVFGGAMLPNFLNALTPGCLVVTPGDRADLVVGSLAAHSAGTPPIAGVLLTLDERPGEAILTLADRLAPGTPVVAVAGRSFPTAAELFALEGKLNAATPRKAETALGLFERHVDTADLLRRVSVARSGRVTPMMFEHVLLEQARADRRRVVLPEGTEDRVLRAADVLLRRDVCELTLLGDVEAIRKKAADLGIDVTPCQIIDPHTSELRQRFAERYAQLRAHKGVTVELAYDVVADVNYFGTLMVQEGLADGMVSGSVHSTAATIRPAFEIIKTKPEASIVSSVFFMCLADKVLVYGDCAVNPDPNAEQLADIAVQAAATARQFGVDPRIAMLSYSTGTSGSGADVDKVREATKLVREARPDLRIEGPIQYDAAVEPSVAATKLPESEVAGQATVLIFPDLNTGNNTYKAVQRSAGAVAVGPVLQGLRKPVNDLSRGALVQDIVNTVAITAIQAQAQQEASA
>CP032698.1|AYG80365.1|2803062_2804292_+|Acetate-kinase
MTTANQGTRVLVLNSGSSSVKYQLLDMRDASRLAVGLVERIGEETSRLKHSPLATGGATREQNGPIADHEAALKAVAAELAVDGLGLDSPELAAIGHRVVHGGLKFSAPTVITDEVLAEIERLVPVAPLHNPANITGIRTAQALRPDLPQVAVFDTAFHTTMPESAARYAIDIETADAHRIRRYGFHGTSHAYVSRETARLLGKAPEDVNVIVLHLGNGASASAVRGGRCVDTSMGLTPLEGLVMGTRSGDIDPAVTFHLMRVAGMSADDIDVLLNKKSGLVGLCGDNDMREIRRRCDEGDEKAQLAFDIYIHRLKKYIGAYYAVLGKVDAIAFTAGVGENAAPVREAAVAGLEELGLAVDGDLNAVRSDRPRLISPEYARVAVAVVPTDEELEIAQQTYALVSPALNS
>CP032698.1|AYG80366.1|2804398_2805829_+|Pyruvate-kinase
MRRSKIVCTLGPAVDSHEQLVALIEAGMSVARFNFSHGSQAEHQARYDRVRKAAEETGRAVGVLADLQGPKIRLAKFAEGPVELVRGDEFTITAEDVPGDKSICGTTYKGLPGDVTKGDPILINDGNVELKVISVEGPRVKTIVIEGGVISDHKGINLPGAAVNVPALSEKDIEDLRFALRMGCDLVALSFVRDADDVKDVHKVMDEVGRRVPVIAKVEKPQAVANMEGVVAAFDGVMVARGDLAVEYPLEKVPMVQKRLVELCRRNAKPVIVATQMMESMITNSRPTRAEASDVANAILDGADAVMLSAESSVGAYPIETVKTMSKIVEAAEEELLSKGLQPLVPGKKPRTQGGSVARAACEIADFLDGKALVAFTKSGDTARRLSRYRTCQPILAFTTDPGTRNQLALSWGVETYVVPHVDSTDAMVDLVDAELLKLKRYSEGDIMVITAGSPPGIPGTTNMVRVHHLGGTEQQ
>CP032698.1|AYG80367.1|2806057_2807302_+|D-alanyl-D-alanine-carboxypeptidase-DacF
MRLPISPQVRRALVALTAAAAAAGAAIGPASASGHLATPPKTPTPGAPGAPAKKEPPAGMSQAGGAQLGQPGDQLGAGAPALPPGLSALSWVVADADTGQVLGARNAHWPLPPASTLKMLFADTVLPAVPHDASRTVSDEDLKGMGDGSSAVGIVPGQTYKAPDLWRGVFLRSGNDAVHVLAAMNGGVEKTVADMQKKAEGLGAKDTHVLSPDGYDAPGQVSSAYDLTLFLRSGLKNRDFTEYCGTASADFPGGPNTKGKPFGISNTNRMLSGIDGVAKYPGLIGGKNGYTTNAGNTLAEAARRDGHTILVTVMNPQENKHDKVYTEMRQLLDWGFSAAGRTQPIGTLDPQAPAAAGSGKGASANGDAAGPGDDGIGALGWAGIGAAVVVAGGAGVLVLGRRRRTSRPQRGRGV
>CP032698.1|AYG80368.1|2807321_2808803_-|hypothetical-protein
MPTTTRPHPPLIQGGMGVAVSGWELARAVAGRGQLGVVSGTALDAVLARRLQLGDPGGHMRRALAAFPVPEAAAYVLDRYFVEGGVVRGERMRAMARLRVERGADAELLTVIGNFVEVWLAKEGHDGLVGVNYLAKIQLATAPALFGAILAGVDYVLVGAGIPGPIPALASRLARAEPVTTLVTVEGDEEPLSHVFDPRGGVMAQLRYGYGPLRRPDVLAIVSLPVLASYLVRDPATRPDGFVIERHRAGGHSAPPRGKLALDDGGEPVYGPRDHPDLAKVAALGIPFWLAGGAAHPERLAEARAMGAVGVQLGSAFALCQESGLRDELRTELRQRARAGTLRVRNDPRASPTAFPFKVAELPGTLSDDPVRAARRPVCDLGYLRTPARAANGGLVYRCAAEPVAAYVRKGGDAVDTAGRMCLCNGLLATVGLGQRRPGGTVEPPVVTLGQDLGFLADLSPDGRPYSAAQVIDWMTGAEALSQTPWPPGSSTG
>CP032698.1|AYG80369.1|2808975_2810349_-|hypothetical-protein
MRGDQTQLDSTGGGDPRERRGPRHAAPRKSLLTKWHMPAGKAMALAAMPTAVLMGMSLTPKLAMADDKTDIPFAPGPCVTRSDSPSASPSPSSSASGKASPSPSASASSKADDKAADDKSADSKTPTPTATGSVGDTVDKLLKPVTPPSAKQPTAAQPPATQTATPPPAKKTNPLDPLGLGDALKGLFGIHDTPTSTPTPSTSTPPAPKPSASTAAPKATAKPSTKPEAKSAKPSTPTAKTGDATLDKTAEAIKKAADEAGQKVTELPDAAKGLDPKLDTAIPDGAKPRFPCPTADPKALAAAKLDGGVPTLPSQPWILKSSKLTLYGLNYEGIVEVKAGETTKKVLKFTASAIDIDNLDQQVYGPEVNGKPTTAHVVARSGSKSTITNGTVTMYTEELKGNLLGLIPITFSPETPPPVNIPIVFFTNVTIRQAGQFGGTLKVPGLHNYVTDGNPTT
>CP032698.1|AYG80370.1|2810338_2810842_-|hypothetical-protein
MSAETTGSRDFRYWRLRFRAWRGHRPFWAGLLTMAGGVPIMYFPYANMHLGNVTLAMSTTAGAGSLIIGVLLVTLGLTMWFHSVVRTFAGVAAILLALISIPIANIGGFVIGFLLSLFGGALACAWVPTKPRRRDKVEAEQVENTPEPGTAATETTVDANGGRNSAG
>CP032698.1|AYG80371.1|2810940_2811642_-|hypothetical-protein
MESQVRGGTRWKRFALVMVPSVAATAAIGVGLAQGALAASFSVSGVDFKVTAEKLDGQNLLQYGSVATGKSLQGQDMHNPVVVSGFSHADISKMCQSVVQPLPMGLGYVTMKLKAGGGQEKIAADNIYLDVSELSTDAKFTHIDIGVAAGEGKRDKDGNLVTSVQPGADGKVAPGSQYGFAQRADRAELSNVEQRAWATTAGSFKLPGLKLSLAVDKDAKKNECGSWQDEFKQ
>CP032698.1|AYG80372.1|2812284_2813253_-|Thioredoxin
MQPRNMSMSGVVDLAAVKAAGEAKSKAEQARAEAARQGGAPAVAPSALVIDVDEATFERDVLTRSSEVPVVIDFWAEWCEPCKQLGPLLERLVVEYNGRLLLAKIDVDANQMLMQQFGIQGIPAVFAVVAGQALPLFQGAAPEAQIRETLDQLVLVAEERFGLTGIPVDPNAQAPAADAQVPAGPYDALLEAAVVALDSGDLAGAAQAYRNVLSDDPGNPEAKLGLAQAELLQRVQSLDPQQVRKDAAEKPADVAAQIAAADLDLVGGHVEDAFGRLVETVRRTFGDDREAARVRLLELFEVIGGDDPRVTAARTALARVLF

Crispr_ID: CP032698_12

• CRISPR_ID: CP032698_12
• CRISPR_location: 2818664-2818743
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_12

Consensus_repeat	Method
TTAGGGGCGCGGGGAACTGCGCGA	CRISPRCasFinder

spacers of CP032698_12

>12.1|2818688|32|CP032698|CRISPRCasFinder
GAAGCGAGCACGGTCCGCAGACCGAAGGGCCT

CRISPR arrays and Neighbor proteins around CP032698_12

CRISPR arrays

The CRISPR arrays of CP032698_12

>merge|CP032698|12|2818664-2818743|CRISPRCasFinder
TTAGGGGCGCGGGGAACTGCGCGAGAAGCGAGCACGGTCCGCAGACCGAAGGGCCTTTAGGGGCGCGGGGAACTGCGCGA

>CP032698|12|10|2818664-2818743|CRISPRCasFinder
TTAGGGGCGCGGGGAACTGCGCGA	GAAGCGAGCACGGTCCGCAGACCGAAGGGCCT
TTAGGGGCGCGGGGAACTGCGCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80382.1|2822808_2824764_-|hypothetical-protein	unknown	unknown	gnl|CDD|199882
CP032698.1|AYG80384.1|2826788_2827082_-|hypothetical-protein	unknown	unknown	gnl|CDD|376658
CP032698.1|AYG80368.1|2807321_2808803_-|hypothetical-protein	unknown	unknown	gnl|CDD|240081
CP032698.1|AYG80375.1|2815238_2816384_-|UDP-N-acetylglucosamine--N-acetylmuramyl--(pentapeptide)-pyrophosphoryl-undecaprenol-N-acetylglucosamine-transferase	unknown	unknown	gnl|CDD|234825
CP032698.1|AYG80380.1|2821125_2821632_-|HTH-type-transcriptional-regulator-MhqR	unknown	unknown	gnl|CDD|197670
CP032698.1|AYG80373.1|2813537_2814185_+|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|379883
CP032698.1|AYG80376.1|2816448_2817144_+|Response-regulator-MprA	unknown	unknown	gnl|CDD|223816
CP032698.1|AYG80385.1|2827078_2827423_-|hypothetical-protein	unknown	unknown	gnl|CDD|378962
CP032698.1|AYG80377.1|2817140_2818544_+|Signal-transduction-histidine-protein-kinase/phosphatase-MprB	unknown	unknown	gnl|CDD|223715
CP032698.1|AYG80387.1|2828218_2828869_+|hypothetical-protein	unknown	unknown	gnl|CDD|376704
CP032698.1|AYG80381.1|2821796_2822804_+|Endoglucanase-A	unknown	unknown	gnl|CDD|376532
CP032698.1|AYG80372.1|2812284_2813253_-|Thioredoxin	unknown	unknown	gnl|CDD|225660
CP032698.1|AYG80383.1|2824767_2826534_-|Cellulose-synthase-catalytic-subunit-[UDP-forming]	unknown	unknown	gnl|CDD|133043
CP032698.1|AYG80369.1|2808975_2810349_-|hypothetical-protein	unknown	unknown	gnl|CDD|223021
CP032698.1|AYG80378.1|2818790_2820491_-|Methylmalonyl-CoA-mutase	unknown	unknown	gnl|CDD|239652
CP032698.1|AYG80371.1|2810940_2811642_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80386.1|2827586_2828219_+|hypothetical-protein	unknown	unknown	gnl|CDD|376704
CP032698.1|AYG80379.1|2820609_2820948_-|hypothetical-protein	unknown	unknown	gnl|CDD|378962
CP032698.1|AYG80370.1|2810338_2810842_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80374.1|2814243_2815242_-|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl|CDD|275033

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80384.1|2826788_2827082_-|hypothetical-protein	gnl|CDD|376658	pfam01910, Thiamine_BP, Thiamine-binding protein. The crystal structure of two of these members shows that this domain has a ferredoxin like fold and is likely to exists as at least homodimers. Sulphate ions are are located at the dimer interfaces, which are thought to confer additional stability. Although the function of this domain remains to be identified, its structure suggests a role in protein-protein interactions possibly regulated by the binding of small-molecule ligands. Solution of the structure of the hyperthermophilic anaerobic Thermotoga maritima sequence, UniProtKB:Q9WYV6, shows that this has a beta-alpha-beta-beta-alpha-beta ferredoxin-like fold and assembles as a homotetramer. It was possible to identify a pocket in each monmer that bound an unidentified ligand. It was also found that it bound charged thiamine though not hydroxymethyl pyrimidine. It is proposed that it is transporting charged thiamine around the cytoplasm. Under oxidative conditions this bacterium is under stress, and the transcriiptional unit within which this protein is expressed is up-regulated in these conditions, suggesting that the chelation of cytoplasmic thaimine is part of the response mechanism to such oxidatvie stress, which is mediated by this family.	8.40122e-31
CP032698.1|AYG80368.1|2807321_2808803_-|hypothetical-protein	gnl|CDD|240081	cd04730, NPD_like, 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase family that reduce a range of alternative electron acceptors. Most use FAD/FMN as a cofactor and NAD(P)H as electron donor. Some contain 4Fe-4S cluster to transfer electron from FAD to FMN.	4.26031e-15
CP032698.1|AYG80375.1|2815238_2816384_-|UDP-N-acetylglucosamine--N-acetylmuramyl--(pentapeptide)-pyrophosphoryl-undecaprenol-N-acetylglucosamine-transferase	gnl|CDD|234825	PRK00726, murG, undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional.	2.55537e-115
CP032698.1|AYG80380.1|2821125_2821632_-|HTH-type-transcriptional-regulator-MhqR	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	9.35108e-24
CP032698.1|AYG80373.1|2813537_2814185_+|putative-HTH-type-transcriptional-regulator	gnl|CDD|379883	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal. This family of bacterial transcriptional repressors is characterized by the short approximately 50 amino acid stretch of residues constituting the helix-turn-helix DNA binding motif, around the YRFhY motif. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. Another target protein is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	1.88906e-15
CP032698.1|AYG80376.1|2816448_2817144_+|Response-regulator-MprA	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.02139e-86
CP032698.1|AYG80385.1|2827078_2827423_-|hypothetical-protein	gnl|CDD|378962	pfam12823, DUF3817, Domain of unknown function (DUF3817). This domain is of unknown function. It is sometimes found adjacent to pfam07690 and pfam03176 which are both transporter domains.	8.80384e-26
CP032698.1|AYG80377.1|2817140_2818544_+|Signal-transduction-histidine-protein-kinase/phosphatase-MprB	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.16492e-55
CP032698.1|AYG80387.1|2828218_2828869_+|hypothetical-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	8.95068e-42
CP032698.1|AYG80381.1|2821796_2822804_+|Endoglucanase-A	gnl|CDD|376532	pfam01341, Glyco_hydro_6, Glycosyl hydrolases family 6.	3.06967e-85
CP032698.1|AYG80372.1|2812284_2813253_-|Thioredoxin	gnl|CDD|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	7.0064e-59
CP032698.1|AYG80383.1|2824767_2826534_-|Cellulose-synthase-catalytic-subunit-[UDP-forming]	gnl|CDD|133043	cd06421, CESA_CelA_like, CESA_CelA_like are involved in the elongation of the glucan chain of cellulose. Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.	8.67121e-80
CP032698.1|AYG80369.1|2808975_2810349_-|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	7.82375e-07
CP032698.1|AYG80378.1|2818790_2820491_-|Methylmalonyl-CoA-mutase	gnl|CDD|239652	cd03680, MM_CoA_mutase_ICM_like, Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, isobutyryl-CoA mutase (ICM)-like subfamily; contains archaeal and bacterial proteins similar to the large subunit of Streptomyces cinnamonensis coenzyme B12-dependent ICM. ICM from S. cinnamonensis is comprised of a large and a small subunit. The holoenzyme appears to be an alpha2beta2 heterotetramer with up to 2 molecules of coenzyme B12 bound. The small subunit binds coenzyme B12. ICM catalyzes the reversible rearrangement of n-butyryl-CoA to isobutyryl-CoA, intermediates in fatty acid and valine catabolism, which in S. cinnamonensis can be converted to methylmalonyl-CoA and used in polyketide synthesis.	0
CP032698.1|AYG80382.1|2822808_2824764_-|hypothetical-protein	gnl|CDD|199882	cd02851, E_set_GO_C, C-terminal Early set domain associated with the catalytic domain of galactose oxidase. E or "early" set domains are associated with the catalytic domain of galactose oxidase at the C-terminal end. Galactose oxidase is an extracellular monomeric enzyme which catalyzes the stereospecific oxidation of a broad range of primary alcohol substrates and possesses a unique mononuclear copper site essential for catalyzing a two-electron transfer reaction during the oxidation of primary alcohols to corresponding aldehydes. The second redox active center necessary for the reaction was found to be situated at a tyrosine residue. The C-terminal domain of galactose oxidase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.	6.00305e-24
CP032698.1|AYG80386.1|2827586_2828219_+|hypothetical-protein	gnl|CDD|376704	pfam01987, AIM24, Mitochondrial biogenesis AIM24. In eukaryotes, this domain is involved in mitochondrial biogenesis. Its function in prokaryotes in unknown.	4.51225e-36
CP032698.1|AYG80379.1|2820609_2820948_-|hypothetical-protein	gnl|CDD|378962	pfam12823, DUF3817, Domain of unknown function (DUF3817). This domain is of unknown function. It is sometimes found adjacent to pfam07690 and pfam03176 which are both transporter domains.	3.65449e-28
CP032698.1|AYG80374.1|2814243_2815242_-|dTDP-glucose-4,6-dehydratase	gnl|CDD|275033	TIGR04180, NAD-dependent_epimerase/dehydratase, NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family. This clade within the NAD dependent epimerase/dehydratase superfamily (pfam01370) is characterized by inclusion of its members within a cassette of seven distinctive enzymes. These include four genes homologous to the elements of the neuraminic (sialic) acid biosynthesis cluster (NeuABCD), an aminotransferase and a nucleotidyltransferase in addition to the epimerase/dehydratase. Together it is very likely that these enzymes direct the biosynthesis of a nine-carbon sugar analagous to CMP-neuraminic acid. These seven genes form the core of the cassette, although they are often accompanied by additional genes that may further modify the product sugar. Although this cassette is widely distributed in bacteria, the family nomenclature arises from the instance in Leptospira interrogans serovar Lai, str. 56601, where it appears as the 30th gene in the 91-gene lipopolysaccharide biosynthesis cluster.	5.2422e-167

Protein sequences

>CP032698.1|AYG80377.1|2817140_2818544_+|Signal-transduction-histidine-protein-kinase/phosphatase-MprB
MSARRRLGVRWRRHRPLRTRLALAASAAVALVAVGVCAGAFFVIRFELYHQLDLNLTQSATLAIQQNRGAAPGVLAGECRYLSAPACAQVVPADPAKDPAKPYLLPVSPPVREVATGERRPYSTNITLPGGEPARMLTTTFGGSGKSLQVALRSDTVRDGVAQAAWLLSGVGAAGVLLAAGLGYGVSRTGLAPVARLTATAEHIAATRDPSHRIELPPGPPHREDEVTRLAASFNTMLGELEQSVTAQRRLVADASHELRTPLTALRTNAELLARADRLTAAQRERASAALGRQIREVSVLVNDLIDLARDEEPTPLLEEVRLAPLLAHTVDTARAHWPATPFRLDLVDASVTLPGVPARLARLISNLLDNAAKFSPPGAPVEVVLSGSELTVRDHGPGIAEADLPHVFDRFYRAERARALPGSGLGLAMARQIARAHGAEVSAHGAPGGGALFRVTLPGAPPPTRP
>CP032698.1|AYG80376.1|2816448_2817144_+|Response-regulator-MprA
MSTTRAVRILVVDDEPEVRAAVEDGLAVEGYEVRGARDGLAALSEVAAWRPDVIVLDVMMPVLDGLGVCRQLRAMGDRTPVLVLTALDSVSERVDGLEAGADDYLVKPFALDELIARVRALLRRAAPDPAEPQELRYADLVVDPVAHTARRGERGIDFTRTEFALLELLMRNPGQVLPRELIHELVWGRDFGPDSNSLAVYVGYLRRKLEAAGEPRLVHTVHGVGYRLDTA
>CP032698.1|AYG80375.1|2815238_2816384_-|UDP-N-acetylglucosamine--N-acetylmuramyl--(pentapeptide)-pyrophosphoryl-undecaprenol-N-acetylglucosamine-transferase
MRTPLSVVIGAGGTGGHIYPGLALAEALRRAVPDAVISFVGTTRGLEGELIPGAGYRLHTVDMIPFDPSLGAKRYLLPAALLKSGAQCRALLKAQGAQVAVGMGGYPSAPVIVGAKMAGLPSLIHESNAVPGRANQFAARLTPHIAVAFDRSRAHLAGGENAVTTGMPIAASLASLDRTALRSEARRALGVPPGARLVLVNGGSLGAARLTAAAVGLAERWRERADVHLLIKTGPAQLTDTQRQLTGLPGARAVPYLDRMDLAYAAADLVVCRAGSATVAELAATGVPAVLVPYPHAPGDHQTHNARVLSDAGAALLVPDAETTAFRLAGLIEPLLANPARLAAMSGAADPGHHAHAADLLAARVLHLASYPTSYTREYAA
>CP032698.1|AYG80374.1|2814243_2815242_-|dTDP-glucose-4,6-dehydratase
MSTTTVWQGRTVLVTGAEGFIGSTLVDLLVELGAHVRAFVHYKPYAEKGHLAHLMDHPSVEMIAGDVRDAGRVSDAVAGCDTVFHLAALIGIPYSYDSPGAYVQTNVVGTENIAEACRRHAVRRLVHTSTSEVYGTALTAPISERHPLQPQSPYSASKIGADMMALSHWHAFELPVTVVRPFNTYGPRQSARAVIPTILAQLHAGVREIKLGSLTPTRDFTYVTDTARGFLAVAECDRALGEVVNLGTGREIAIGDLARALITASGREASVVADPARLRPSGSEVERLLSDNTRAREWAGWQPEVSLEDGLKRTSAWVEENLSLFAPGRYQV
>CP032698.1|AYG80373.1|2813537_2814185_+|putative-HTH-type-transcriptional-regulator
MVADMPSSSRAARRSCTGRTGRPRSAEADAAILLATREALVDLGWSKLTMGDVATRAGVAKTTLYRRWAGKNELVVDAVAVLFDELELPDLGSLVADVEGVVLQFAALLERPETKTALMAVVAESTRDDALRGRIRSAIVDRQKRLVLVGRERAQARGELPYETDPVVSARHTDLIFDVVAGAVVHRALVSAEPVDEEWAREFTLLICSGLAATA
>CP032698.1|AYG80372.1|2812284_2813253_-|Thioredoxin
MQPRNMSMSGVVDLAAVKAAGEAKSKAEQARAEAARQGGAPAVAPSALVIDVDEATFERDVLTRSSEVPVVIDFWAEWCEPCKQLGPLLERLVVEYNGRLLLAKIDVDANQMLMQQFGIQGIPAVFAVVAGQALPLFQGAAPEAQIRETLDQLVLVAEERFGLTGIPVDPNAQAPAADAQVPAGPYDALLEAAVVALDSGDLAGAAQAYRNVLSDDPGNPEAKLGLAQAELLQRVQSLDPQQVRKDAAEKPADVAAQIAAADLDLVGGHVEDAFGRLVETVRRTFGDDREAARVRLLELFEVIGGDDPRVTAARTALARVLF
>CP032698.1|AYG80371.1|2810940_2811642_-|hypothetical-protein
MESQVRGGTRWKRFALVMVPSVAATAAIGVGLAQGALAASFSVSGVDFKVTAEKLDGQNLLQYGSVATGKSLQGQDMHNPVVVSGFSHADISKMCQSVVQPLPMGLGYVTMKLKAGGGQEKIAADNIYLDVSELSTDAKFTHIDIGVAAGEGKRDKDGNLVTSVQPGADGKVAPGSQYGFAQRADRAELSNVEQRAWATTAGSFKLPGLKLSLAVDKDAKKNECGSWQDEFKQ
>CP032698.1|AYG80370.1|2810338_2810842_-|hypothetical-protein
MSAETTGSRDFRYWRLRFRAWRGHRPFWAGLLTMAGGVPIMYFPYANMHLGNVTLAMSTTAGAGSLIIGVLLVTLGLTMWFHSVVRTFAGVAAILLALISIPIANIGGFVIGFLLSLFGGALACAWVPTKPRRRDKVEAEQVENTPEPGTAATETTVDANGGRNSAG
>CP032698.1|AYG80369.1|2808975_2810349_-|hypothetical-protein
MRGDQTQLDSTGGGDPRERRGPRHAAPRKSLLTKWHMPAGKAMALAAMPTAVLMGMSLTPKLAMADDKTDIPFAPGPCVTRSDSPSASPSPSSSASGKASPSPSASASSKADDKAADDKSADSKTPTPTATGSVGDTVDKLLKPVTPPSAKQPTAAQPPATQTATPPPAKKTNPLDPLGLGDALKGLFGIHDTPTSTPTPSTSTPPAPKPSASTAAPKATAKPSTKPEAKSAKPSTPTAKTGDATLDKTAEAIKKAADEAGQKVTELPDAAKGLDPKLDTAIPDGAKPRFPCPTADPKALAAAKLDGGVPTLPSQPWILKSSKLTLYGLNYEGIVEVKAGETTKKVLKFTASAIDIDNLDQQVYGPEVNGKPTTAHVVARSGSKSTITNGTVTMYTEELKGNLLGLIPITFSPETPPPVNIPIVFFTNVTIRQAGQFGGTLKVPGLHNYVTDGNPTT
>CP032698.1|AYG80368.1|2807321_2808803_-|hypothetical-protein
MPTTTRPHPPLIQGGMGVAVSGWELARAVAGRGQLGVVSGTALDAVLARRLQLGDPGGHMRRALAAFPVPEAAAYVLDRYFVEGGVVRGERMRAMARLRVERGADAELLTVIGNFVEVWLAKEGHDGLVGVNYLAKIQLATAPALFGAILAGVDYVLVGAGIPGPIPALASRLARAEPVTTLVTVEGDEEPLSHVFDPRGGVMAQLRYGYGPLRRPDVLAIVSLPVLASYLVRDPATRPDGFVIERHRAGGHSAPPRGKLALDDGGEPVYGPRDHPDLAKVAALGIPFWLAGGAAHPERLAEARAMGAVGVQLGSAFALCQESGLRDELRTELRQRARAGTLRVRNDPRASPTAFPFKVAELPGTLSDDPVRAARRPVCDLGYLRTPARAANGGLVYRCAAEPVAAYVRKGGDAVDTAGRMCLCNGLLATVGLGQRRPGGTVEPPVVTLGQDLGFLADLSPDGRPYSAAQVIDWMTGAEALSQTPWPPGSSTG
>CP032698.1|AYG80378.1|2818790_2820491_-|Methylmalonyl-CoA-mutase
MDADAIEEGRRRWQARYDKARKRDADFTTLSGDPVDPAYGPRPGDTYDGFERIGWPGEYPFTRGLYPTGYRGRTWTIRQFAGFGNAEQTNERYKMILAAGGGGLSVAFDMPTLMGRDSDDPRSLGEVGHCGVAIDSAADMEVLFQDIPLGDVTTSMTISGPAVPVFCMYLVAAERQGVDPGVLNGTLQTDIFKEYIAQKEWLFQPEPHLRLIGDLMEHCAKGIPAYKPLSVSGYHIREAGATAAQELAYTLADGFGYVELGLSRGLDVDVFAPGLSFFFDAHVDFFEEIAKFRAARRIWARWMKEVYGAESDKAQWLRFHTQTAGVSLTAQQPYNNVVRTAVEALAAVLGGTNSLHTNALDETLALPSEQAAEIALRTQQVLMEETGVANVADPLGGSWYVEQLTDRIEADAEKIFDQIRERGTRAHPDGQHPIGPITSGILRGIEDGWFTGEIAESAFRYQQSLEKGDKRVVGVNCHHGSVTGDLEILRVSHEVEREQVRALADRKSRRDDAAVTAALEAMLAAARDGSNMIVPMLEAVRAEATLGEICGVLREEWGTYTEPPGF
>CP032698.1|AYG80379.1|2820609_2820948_-|hypothetical-protein
MKKSVLTRYRVMAYVTGVLLVLLTLGVIAKYILDMNGAADFTKIIGIAHGWLYVIYLVFAFDLGSKAKWPVGKQLWVLIAGTIPTAAFFVERKVSKELEPKVVDTVPAGAGA
>CP032698.1|AYG80380.1|2821125_2821632_-|HTH-type-transcriptional-regulator-MhqR
MPKPLSLPFDPIARADELWTQRWGPVPSMGAITSIMRAHQILLAEVDAVVKPYGLTFARYEALVLLTFSKEGELPMSKIGERLMVHPTSVTNTVDRLVKSGLVDKRPNPNDGRGTLASITDKGREVVERATRDLMAMDFGLGVYDAEECGEIFAMLRPLRVAANDFDS
>CP032698.1|AYG80381.1|2821796_2822804_+|Endoglucanase-A
MSRYRSLALLAALVFTAVVGCSSGADPGEGSAIRVATSAAPAPGAPFWVDPESDAARQVELWRGQGRTADAQVLRRIAERPVATWPSGDDPRPGIRKAVEGAAKEKRTALFVAYDIPHRDCGKYSAGGADGVEGYRAWIGMFAEAIGDAPALVVLEPDAVAHMVDGCTTPDHHAERYQLLGEAIERLKGLPRTKVYLDAGNPSWIPDPQSLVEPLRRAGIDRADGFALNVSNFHTDATVRAYGAKLSQALDGKHFVMDTSRNGEGPLLDGRDQAWCNPPGRSLGSPPSVRTGDPLVDAYLWIKRPGDSDGPCRGGPSAGTWWPEYALGLARRARF
>CP032698.1|AYG80382.1|2822808_2824764_-|hypothetical-protein
MAFRPSKRTKKTLLGGGAVVVLAGLNAPAAVSFATAQYHAYEIAQPEYMRQYGAWHGVDIPKDYRTNAIHAALLHTGKVLIIAGSGNKQTHFDAGTFDTVLWNPKDNSFKKIPTPEDFFCGGHAQLPDGKLLVAGGTARYEVLDGEVKRAGGGMRVKNEDPNKPVTLKKGTKFRSPSGVEYVSKFDVTVGRAKREFEISYYASGQMKPWKTKTTAAEARVFVEAVNEGPQSVATDQAQYEVEGLTGKDADNVYGLAEKITLDKQDYQGIRAAYEFDPKAEKYIPVAPMKEARWYPTLTTLKDGRVLAVSGLDDVGAIIQGDNEIYDPKSKQWSKGPFRYFPTYPSLFLTKSGKLFYSGANAGYGPADKGREPGLWDVEKNTFTKIGGLNAGDQLETASSLLLPPAQDQRFMLLGGGGIGESKKATPRTAVVDLNQNNPAFTSGPELPQGTRYLNSVLMPDDSVFTTGGSSDYRGRGGSNVLSAQFYDPKANAFREAADPTIGRNYHSEALLLPDGRVATFGSDSLFGDKNNTKPGKFEQRMEIYTPPYLYRDKDKRPALGDGPEAAAADGRATFRTDHPERVVKARLMRPSAVTHTTDVEQRSIELGLTKDKNSVTVTVPKDRALVPPGWYMVFVTDAENTPSEAKWLRVD
>CP032698.1|AYG80383.1|2824767_2826534_-|Cellulose-synthase-catalytic-subunit-[UDP-forming]
MRPEGYDYATHSRLAGPLTEPGAKPYRVQYRSLLSQEPHRIRAVLLMTLAPILTGLLLVYLVWPTHWVEREGGDRWLVDLDITMLVSIALIELFMVANVASVAHATMVARDPVPVTPEEGTRVAFLTTYVPGKEPISMVRGTLEAAVRLTHTGPLDIWLLDEGDDERAKALCAELGVRHFTRKGVPEWNTKKGAHKARTKHGNYNAWIAMHGGGYDFFASVDTDHAPLPNFLERMMGYFRDPDVAFVVGPQVYGNYDSPVTKAAESQQFLFHALIQRAGNRYRAPMFVGTNNVVRIAALRQIGGLYDSITEDMATGFELHRHKNPRTGHHWRSVYTPDVLAVGEGPASWTDFFTQQMRWSRGTYETLVKQYWKAPFTMPPGRLLSYTLMLVYYPMTAVNWLLGIVSCVLFLWFGASGTEVTASVWLMLYSDAAALQVGLYLWNRRHNVSPHEPEGSGGLAGMGMSALSAPIYLKSLGSALLRTRGRFVVTPKGGQASPDRLWTFRIHLFWAAVLACSLAASVRYGHTHAAMRTWAVLALCIALAPAAIWAWTAVRARTAARGAAKAAGPQPKATGEAEPAIATPTGGN
>CP032698.1|AYG80384.1|2826788_2827082_-|hypothetical-protein
MIVAFSVSPLGVGEDVGEYVADAVRVVRESGLPNRTDAMFTSIEGEWDEVMDVVKRAVAAVEARSNRVSLVLKADIRPGVTDGLTSKVETVERHLST
>CP032698.1|AYG80385.1|2827078_2827423_-|hypothetical-protein
MDLKTASALHRLRLISLPEAISFPILLVCSVLKRTTSFDGVMVMGMVHGVLFTLYVLFWLDAWNRTKWSVKTGALYFVLAVLPFGGFYAERKIRRELDDAVIATRARKEGVVNA
>CP032698.1|AYG80386.1|2827586_2828219_+|hypothetical-protein
MFRLQGSKVLAVSMTGDAVKAKNGSMVAYDGQMAFKKMSGGGEGLRGMVTRRLTGEQMTVMEVKGHGTCYFADRASEINLVSLQGDKLFVESSNLLATDAGLRTGTTFTGLRGASQGNGLFTTTIEGHGQAAIMSDGPAVVLRVSAQSPLSVDPGAYIAHQGNLQQHFQSGVTFRTFLGEGSGEAFQIRFEGEGLVYVQPSERNTIGGDV
>CP032698.1|AYG80387.1|2828218_2828869_+|hypothetical-protein
MPFREINSKMVEATVAPGQKMFSQRGAMLAYKGEVSFTPNIQGGQGGLMSMIGRRVANEATPLMTVEGSGTVMFGHGGHHIQVINLQGDTLYVEADRLLAFDGTLQQGTMFMGSQGGVMGMVRGQVTGQGLFTTTLKGHGAVAVMAHGGVIELPITPQRPVHVDPQAYVAHHGDVRNKLSTALGWRDMVGRGSGEAFQLELSGQGSVYVQASEDKL

Crispr_ID: CP032698_13

• CRISPR_ID: CP032698_13
• CRISPR_location: 2908700-2908836
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_13

Consensus_repeat	Method
ATGAACGGGGTCAGCCGGCGGCTGTGGAGGAGCTCGGGACTGCTGGC	CRISPRCasFinder

spacers of CP032698_13

>13.1|2908747|43|CP032698|CRISPRCasFinder
CTGACGACATAGCCACGCGGCGGAGCCGCACATAGGACGCAGC

CRISPR arrays and Neighbor proteins around CP032698_13

CRISPR arrays

The CRISPR arrays of CP032698_13

>merge|CP032698|13|2908700-2908836|CRISPRCasFinder
ATGAACGGGGTCAGCCGGCGGCTGTGGAGGAGCTCGGGACTGCTGGCCTGACGACATAGCCACGCGGCGGAGCCGCACATAGGACGCAGCATGAACGGGGTCAGCCGGCGGCTGTGGAAGAGCTCGGGACTGCTGGC

>CP032698|13|11|2908700-2908836|CRISPRCasFinder
ATGAACGGGGTCAGCCGGCGGCTGTGGAGGAGCTCGGGACTGCTGGC	CTGACGACATAGCCACGCGGCGGAGCCGCACATAGGACGCAGC
ATGAACGGGGTCAGCCGGCGGCTGTGGAAGAGCTCGGGACTGCTGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80461.1|2912487_2913105_-|hypothetical-protein	unknown	unknown	gnl|CDD|225138
CP032698.1|AYG80463.1|2913489_2914005_-|Serine-protease-inhibitor	unknown	unknown	gnl|CDD|214939
CP032698.1|AYG80453.1|2903548_2904940_+|putative-FtsW-like-protein	unknown	unknown	gnl|CDD|223843
CP032698.1|AYG80450.1|2900800_2901577_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80458.1|2909605_2909905_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80464.1|2914001_2916695_-|hypothetical-protein	unknown	unknown	gnl|CDD|377989
CP032698.1|AYG80465.1|2917031_2917817_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80448.1|2899386_2900184_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80466.1|2917849_2918290_-|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
CP032698.1|AYG80447.1|2898437_2899355_+|DNA-ligase-C	unknown	unknown	gnl|CDD|185714
CP032698.1|AYG80459.1|2910007_2911171_+|putative-endopeptidase	unknown	unknown	gnl|CDD|366353
CP032698.1|AYG80455.1|2906523_2907630_-|hypothetical-protein	unknown	unknown	gnl|CDD|153097
CP032698.1|AYG80457.1|2908869_2909595_+|Transcriptional-repressor-Mce3R	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG80462.1|2913085_2913493_-|hypothetical-protein	unknown	unknown	gnl|CDD|283084
CP032698.1|AYG80460.1|2911167_2912439_-|Styrene-monooxygenase-StyA	unknown	unknown	gnl|CDD|380046
CP032698.1|AYG80452.1|2902994_2903336_+|hypothetical-protein	unknown	unknown	gnl|CDD|377965
CP032698.1|AYG80451.1|2901573_2902893_+|Sensor-protein-CseC	unknown	unknown	gnl|CDD|223715
CP032698.1|AYG80449.1|2900339_2900645_+|hypothetical-protein	unknown	unknown	gnl|CDD|379915
CP032698.1|AYG80454.1|2904936_2906400_+|Penicillin-binding-protein-A	unknown	unknown	gnl|CDD|274573
CP032698.1|AYG80446.1|2897556_2898441_+|Multifunctional-non-homologous-end-joining-DNA-repair-protein-LigD	unknown	unknown	gnl|CDD|240133

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80461.1|2912487_2913105_-|hypothetical-protein	gnl|CDD|225138	COG2229, COG2229, Predicted GTPase [General function prediction only].	3.22716e-42
CP032698.1|AYG80463.1|2913489_2914005_-|Serine-protease-inhibitor	gnl|CDD|214939	smart00960, Robl_LC7, Roadblock/LC7 domain. This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	3.2134e-13
CP032698.1|AYG80453.1|2903548_2904940_+|putative-FtsW-like-protein	gnl|CDD|223843	COG0772, FtsW, Bacterial cell division membrane protein [Cell division and chromosome partitioning].	1.75602e-71
CP032698.1|AYG80464.1|2914001_2916695_-|hypothetical-protein	gnl|CDD|377989	pfam08376, NIT, Nitrate and nitrite sensing. The nitrate- and nitrite sensing domain (NIT) is found in receptor components of signal transducing pathways in bacteria which control gene expression, cellular motility and enzyme activity in response to nitrate and nitrite concentrations. The NIT domain is predicted to be all alpha-helical in structure.	3.58803e-25
CP032698.1|AYG80466.1|2917849_2918290_-|putative-HTH-type-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.25585e-17
CP032698.1|AYG80449.1|2900339_2900645_+|hypothetical-protein	gnl|CDD|379915	pfam17032, zinc_ribbon_15, zinc-ribbon family. This zinc-ribbon region is found on a set of largely microsporidia-specific proteins.	1.34713e-06
CP032698.1|AYG80447.1|2898437_2899355_+|DNA-ligase-C	gnl|CDD|185714	cd07905, Adenylation_DNA_ligase_LigC, Adenylation domain of Mycobacterium tuberculosis LigC-like ATP-dependent DNA ligases. Bacterial DNA ligases are divided into two broad classes: NAD-dependent and ATP-dependent. All bacterial species have a NAD-dependent DNA ligase (LigA). Some bacterial genomes contain multiple genes for DNA ligases that are predicted to use ATP as their cofactor, including Mycobacterium tuberculosis LigB, LigC, and LigD. This group is composed of ATP-dependent DNA ligases similar to Mycobacterium tuberculosis LigC. ATP-dependent polynucleotide ligases catalyze phosphodiester bond formation using nicked nucleic acid substrates with the high energy nucleotide of ATP as a cofactor in a three step reaction mechanism. DNA ligases play a vital role in the diverse processes of DNA replication, recombination and repair. Members of this group contain adenylation and C-terminal oligonucleotide/oligosaccharide binding (OB)-fold domains, comprising a catalytic core unit that is common to all members of the ATP-dependent DNA ligase family. The adenylation domain binds ATP and contains many of the active-site residues. The common catalytic core unit comprises six conserved sequence motifs (I, III, IIIa, IV, V and VI) that define this family of related nucleotidyltransferases.	1.23959e-74
CP032698.1|AYG80455.1|2906523_2907630_-|hypothetical-protein	gnl|CDD|153097	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	1.30841e-14
CP032698.1|AYG80457.1|2908869_2909595_+|Transcriptional-repressor-Mce3R	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	3.26822e-10
CP032698.1|AYG80462.1|2913085_2913493_-|hypothetical-protein	gnl|CDD|283084	pfam05331, DUF742, Protein of unknown function (DUF742). This family consists of several uncharacterized Streptomyces proteins as well as one from Mycobacterium tuberculosis. The function of these proteins is unknown.	4.50865e-35
CP032698.1|AYG80460.1|2911167_2912439_-|Styrene-monooxygenase-StyA	gnl|CDD|380046	pfam17885, Smoa_sbd, Styrene monooxygenase A putative substrate binding domain. This domain is found in the 46 kDa FAD-specific styrene epoxidase (SMOA) protein, comprises a part of the styrene monooxygenase (SMO) two-component flavoprotein monooxygenase enzyme. Structural analysis indicates that SMOA monomer comprises two globular domains spanned by a long alpha-helix. This domain contains a putative substrate binding site.	1.02701e-58
CP032698.1|AYG80452.1|2902994_2903336_+|hypothetical-protein	gnl|CDD|377965	pfam08239, SH3_3, Bacterial SH3 domain.	4.44037e-07
CP032698.1|AYG80451.1|2901573_2902893_+|Sensor-protein-CseC	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.50304e-35
CP032698.1|AYG80459.1|2910007_2911171_+|putative-endopeptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	6.483e-24
CP032698.1|AYG80454.1|2904936_2906400_+|Penicillin-binding-protein-A	gnl|CDD|274573	TIGR03423, pbp2_mrdA, penicillin-binding protein 2. Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	1.43897e-76
CP032698.1|AYG80446.1|2897556_2898441_+|Multifunctional-non-homologous-end-joining-DNA-repair-protein-LigD	gnl|CDD|240133	cd04863, MtLigD_Pol_like, MtLigD_Pol_like: Polymerase (Pol) domain of bacterial LigD proteins similar to Mycobacterium tuberculosis (Mt)LigD. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required for non-homologous end joining (NHEJ)-mediated repair of DNA double-strand breaks (DSB). NHEJ-mediated DNA DSB repair is error-prone. MtLigD is monomeric and contains an N-terminal Pol domain, a central phosphoesterase module, and a C-terminal ligase domain. It has been suggested that LigD Pol contributes to NHEJ-mediated DNA DSB repair in vivo, by filling in short 5'-overhangs with ribonucleotides; the filled in termini would then be sealed by the associated LigD ligase domain, resulting in short stretches of RNA incorporated into the genomic DNA. The MtLigD Pol domain is stimulated by manganese, is error-prone, and prefers adding rNTPs to dNTPs in vitro. The MtLigD Pol domain has been shown to prefer DNA gapped substrates containing a 5'-phosphate group at the gap.	4.44078e-101

Protein sequences

>CP032698.1|AYG80455.1|2906523_2907630_-|hypothetical-protein
MSTHDLYVKAPQEPHWQVPASGSARFSWEYDDGRDRLLALYQKGKDKQWDGAKRIDWSLEVDPHDPLGTPDEAMTLYGTPYWAKMTDRDKGELRLHYTSWQFSQFLHGEQGAMVCAARIVESVPDLDAKFYSATQTMDEARHAEIYGRFLHEKLGMLYPVNDNLQALLGDTLRDSRWDMPYLGMQVLIEGLALAAFGMIRDTTDKPLPKQILAYVMQDEARHVAFGRMALRDYYQQLSDAELKEREEFVIEGCYLMRDRLRGVEVLENFGIPKKEAERLSEESEFLHLFRKLLFSRIVPCVKDIGLWGERLQKAYLDMGVFDLGDSNLDLLMSQDEEIAEQLDKERFAEEEAARVAEVEGAIEEGAAS
>CP032698.1|AYG80454.1|2904936_2906400_+|Penicillin-binding-protein-A
MTRYIRRAAAFCLVLLVALLVNAARVQVLQADALDANPANRRLAIARYHQPRGAIVVGNESVTGSRDSGQQLRYERTYKNGPLYAPVTGYASQTYGTTLVENAEDAVLSGTSSLLSVFPLWNDLTRGRHSGGRAVTTVNASMQQAAYAGLGGKKGAVAALEPATGRILALVSSPSYEPGVLSGTGRAVESAWSRLTKDADQPMLNRAIRGTYPPGSAFKIVTAAAALDAGVVTDVDAPTDTPDPYVLPNTSTTLPNEASGCGNASLTYAVTVSCNTVMAGLGVKVGLPRMLEAVRKFGFNDTKLRVPSGVAKSNFDTRMSPDQLALSSIGQFDTTATPLQMAMVSAAVANGGDLKYPYLVERTTTSRGTTVSTTRPRTYQRAMNPATAMRLRQMMIDVVRTGTGTSAAIPGATVGGKTGTAQNGVGNIGSPYAWFISWAQADGAVRPAVAVAVVVEDASANRGDISGGGDAAPIAKAVMEAALAARP
>CP032698.1|AYG80453.1|2903548_2904940_+|putative-FtsW-like-protein
MTAPSAADTFPPELRLPKRRGVELFLLVGAVVVVVLGYVAVGLARTGTLPPDAARYAAGLGLLALLTHLVVRFRAPYADPLLLPIAVLLNGLGLVLIYRLDLATPGSRAAPAQLVWSTLGVGLFLVVVLVLRDHRVLQRYAYLSMAAALVLMLVPILFPPVNGAKIWVRAAGLSFQPAEFAKILLALFFAAHLAANRNALAYTGRRVWRLQLPTGRVLGPIVAVWLLSVGVLVLERDLGTSLLFFGLFVIMLYVATGRIGWIAVGLLLASAGAAAVALFEPHVHARVTDWLNPYATIEAGLGPSQLAQSLFAFAAGGTLGTGLGLGHSVLIGFAARSDFILATAGEELGLSGLTAIFLLYALLVARGYRAGLSLPSPFGRLFAIGLASILALQVFVIAGGVMGLIPLTGMAMPFLAQGGSSVVTNWIIVALLIRISDSARRPLPVVETGVIARPEAPVEGTVK
>CP032698.1|AYG80452.1|2902994_2903336_+|hypothetical-protein
MFLRSPLAALALCVATGAAAVLATTSPAAADQSAHQEYKGRVTAKGGLILRDRPTRSSRIVGKAPYGSIVHIFCKTGGDRVNGNDRWYLLTDGTWAWGSAYYIDNIGAVPRWC
>CP032698.1|AYG80451.1|2901573_2902893_+|Sensor-protein-CseC
MRLPRAPRLPLPAWTATLTWKAAVFITVMCCALAALLGVLVHVSVTRQTVGEARNKALDRLMDVTRMYEAGEQLPPGSGLDPPQLPASLRALAVSGRRGTLVDDDNGRPTMWAAGPADGKALAAEIDYTQSARTINGLDKAILGSSILAIGATLLVGVFAVTRITRRLHQTATVARRIDAGDLDARVNDPRTKDPSRHQDEVATVAGALDTMASTLQGKLLSEQRFTADVAHELRTPLTGLHAAAELLPEGRPAELVRDRVRAMRSLTEDLLEISRLDAGSETVDLDLQQLAPVVERVVRGSVASGTAEADTTVTVVRDACVETDKRRLERVVGNLVANAHRHGKAPVELTVHGPVVTVRDHGTGYPDYLLDHGPQRFRTDAGSKGHGLGLTIAVGQAAVIGAELTFSNAPDGGAVARLELPEYVDLESPAGEGAPNGE
>CP032698.1|AYG80450.1|2900800_2901577_+|hypothetical-protein
MIRQRRTALLAPLLTAVGALALSGCGGAGQLESSGATPTAVGPIHLWPGLAPATATPNDYGETDTEQVPGIKVTGGDVHKLNPVAVVQAEVKAHPNTYSGEDGLYDETVRQLAMCKQKPAGCPVLKPYYRDLTGDGRDELILGIRMPDQNLAVRCYMPAKDGGLIRIMSTVDQIISVDLAGRDVILRSVATGMSGYEYRTAWSWDDHQQAMLPTRDEIVRNKPGGKHPAPTGAGQIPPSPKKKPPAASQSATPTADAP
>CP032698.1|AYG80449.1|2900339_2900645_+|hypothetical-protein
MIIFGSRGYLYQLAMLTLVCGNCGNPSAHSLRKYVTKFTLFFVPLFPFSTKYRTQCTFCGLEQQITKEQAEGLLAQPVAPQQAYGQQPQPGQMQGQNPYQQ
>CP032698.1|AYG80448.1|2899386_2900184_-|hypothetical-protein
MAGLRVTPVHRHGQARLYVSLPDGRSAAWYDRATGRVSLLLDDHRDEVLAALRPYVVGELLVGPPPVPTPSDLARLALHPDDDLAPNRPGEALLTELERYGSAHRLRSDPRRRELAAQQATGAALDRLDGAGWRVLHSVPLPADATIHHLLIGPAGALTVRALDARRHRVRIADPLVAVGRGAPSPLLRTARHDAERASLALAAAVRAVVVLVGAARVERGPAPDVSVLRDTEIADLGRLGGVLKPADVESLYWTARDRRTWLRA
>CP032698.1|AYG80447.1|2898437_2899355_+|DNA-ligase-C
MSAEALRPPLAVALAEAVATLPRGAGWAYEPKFDGHRMVVFRTAERVVLQARSGRIITAAFPDLADAARELAPGTVLDGEVVVWTQGRTDFAAVQRRAAATPARAPLLARRLPASYAAFDLLAQAGRDLRAEPYERRRARLVEVLGPLGPPLQAVPMTTSVETALTWYETLPASGIEGLVAKRLNGPYRSGHRAWRKVRHTDTREAVVIGHTGGPNRPAALVLVLPGDDVPVVSSPLPAALRAEAGRALAPLAAEGGGTAVAAGLGEVAYRAVAPGLLAEVEWATTRHAGATVLRLREAGGEAGG
>CP032698.1|AYG80446.1|2897556_2898441_+|Multifunctional-non-homologous-end-joining-DNA-repair-protein-LigD
MTPITEVEGRRVALSNLDKVLYPATSTTKGELLHYCASVAGPFLAQLDDRPVSFLRFPDGPGGQRFFTKNPPPSTPTWVKTAEVPRTEDKAARQVVVSDLATLMWAANLVVEFHTPQWRAAAPGLADRLVLDLDPGEPASIVECCAVARWLRDRLAADGLSAYAKTSGSKGLHLLSALEPTPSAQVSAYAKKLAREAEAALAGLVTHKMAKALRPGKVFVDFSQNAAAKTTATPYTVRAKDRPTVSAPVSWEEVEACTDPADLTFLITDIAPRLERDGDLLAPLFDPAGAGRLP
>CP032698.1|AYG80457.1|2908869_2909595_+|Transcriptional-repressor-Mce3R
MTSPAATPAYRRLSVEERRTQLLGAALSLFAHRAPEDVSLDDVAEAAGVSRPLVYRYFPGGKQQLYEAALRSAADELELCFAEAQSGPLTQRLTRVLDRYLTFVDEHDAGFSALLQGGSMAETSRTTAIVDEVRRAAAEQILVHLEVAEPGPRLRMMVRTWIAAVEAASLIWLDEDKQPPLAELRDWLVDHLVALLTVTAATDEQTAAAVRGALAHESAEGAAGVLARRVIPVVSGAGHLL
>CP032698.1|AYG80458.1|2909605_2909905_+|hypothetical-protein
MRSENTLFVGGPLDGRVLPVLTGPTGKPPQWYEVPVPDAEGGPATVYAYRLEPASHTKRLGLPRGWKYTYVPEGREPRRWPWTKKGGGASPRTGVPPHE
>CP032698.1|AYG80459.1|2910007_2911171_+|putative-endopeptidase
MSARVRSVCAMAVAAALATAAVGPLAVAAPQPPGESSTVLPAGPEASASALLTQLQTLFRQTEEATEAYNATDVELKRREEEDKKLAASLATARSALAHSRGEAGRLAREQYQGRSELSTYLRLLLARDPQSALDQRHVLDRAAGERQAAVDRLTHGEQRAADLARASRQALDEQQALARRQRQAKDDVELRLKEVEKLLADLSPEQLAELTRLEAQGTEKAQESLLASGALSGTRAPSAAGDRALTYAVEQIGKPYVWGAEGPESYDCSGLTSQAWAHAGRAIPRTSQEQWAELPRVPLTSLRPGDLVIYFPTATHVAMYLGDGLVVQAPRPGSHVKVSPIAANPLLGAVRPDPAADALSSYHPPKLPEGAAQGVDTGYSAESGPA
>CP032698.1|AYG80460.1|2911167_2912439_-|Styrene-monooxygenase-StyA
MRRILIVGAGQSGLQLALGLQAQGYEVTLMSNRTADEIRSGRVMSTQCMFHTALQHERDLGLNFWESQAPRIEGVGVSVAAPDATRAIDWVGKLKGYAQSVDQRVKMAGWMETFAQRGGQLVIHGAAVSDLDFFARTYDLVLVSAGKGELVSMFGRDASRSPYTEPQRALAVSYVHGLGPRPEHPEFDAVRCNLVPGVGELFVMPTLTTSGRADILFWEGVPGGPLDVFNGVTDPAEHLSLTLELMEKFLPWEYARATKVELTDGGGTLAGRYAPTVRNPIGRLPGGGLVLGVADVVVANDPITGQGSNSASKCAASYLSSIVEHGEKEFDEAWMRSAFDRYWDTAQHVTKWTNAMLGVPPEHVLNLIGAAGQLQPAADRFANGFDDPADFENFFYEPEKTAAYLAEVAGAQAQAQTQTQTQA
>CP032698.1|AYG80461.1|2912487_2913105_-|hypothetical-protein
MDSAASELLVPDEELLPWQQDRSKAPIATKVVVAGGFGVGKTTFVSAVSEITPLQTEAVMTQASEATDDLSATPDKVTTTVAMDFGRITLDDDLVLYVFGTPGQQRFWFMWDDIVRGAIGAIVLADTRRLSDCFPALDYFESCGLPYIVAVNHFEGTESFEPEDVREALTVAPHIPVVIMDARDRASVIESLLGLVAHALEACPE
>CP032698.1|AYG80462.1|2913085_2913493_-|hypothetical-protein
MTPPAEKSARLPIRGADKKPARVRPYSLTGGRTRFGHVLLVETFVAAIEAPPERKELGGRTHRVMPEMLAIVEICRAMRTVAEISALLKMPLGVVRVLLSDLADQGRIRVYGTGHSPGQPNRALLERVLSGLRRL
>CP032698.1|AYG80463.1|2913489_2914005_-|Serine-protease-inhibitor
MSATGTGIGRPGSTTSGTGTITGSTEARNLRWLLGNLVEEVPGIHSVAVVSSDGLLLLSSDPEQRQTPVAQQGPRGSSADLATIVSGIGSLTVGAARLMDGGGVKQTMVAMEEGSVFVMSISDGSLLGVHATPDCDMSVVAYHMALFVGRAGHVLTPEVRSELRQSMEAAQ
>CP032698.1|AYG80464.1|2914001_2916695_-|hypothetical-protein
MQNKRPRGNDDTRAQRTVRVRSRLVVSVAVVSLTVLGAGAPTLFAASADLTDSQHLVTLAQLDQQAISLAHALGDERDGVTRYVASGRPAGKDAALKEPAARVDRKIDELRATAPAGLARDLATVPALRRTALTGKGTALEAQKAYSDVIATLLAVADELADRTPPRAAEAVRAPGALGRAAEQASATRGLLLGALSVPAGQTSRVFDPLTGKYVQKEKDDGDAGRARDALSTAAQQAHVREQAALADFDQAAGADARDKVATTVTGPEVEAADGFLTRLTDQPQLSAAERKSDPDAVDAALSARIDRMRGAEAALATAEVKRFEQLRDDDVSALEIRVGLIGALLLLAIGVSAATARSLTRPLAVLRRGSARLAEAPESAEPVRFTGRNDEFARVVRSLNELHEKFGERHARAAELDADLAKQRGRLARLAAEKDELRSRVRELTDELERAHGTVKHAFVNLGLRSLGLIERQLSVIEGLEEREQDPDQLGVLFKLDHLATVIRRHGENLLVLAGTEHHHNHPGPVPLVDVMRAAVSEIERYERVVIQALPPHAQVAGFAADDLSHLVAELLENATSFSPPEAQVQLSGWQLEGGDIMLSVQDEGIGVPPERRAELNRRLADPSSYEPGEPGTDSGGLGLHVSALLAHRHGVRIELREQKQGGVAAVVVLPQAILPAAPPEAMPHLMTAPDDAPRFTLPGALAEANSNVLPERTERSGEMARPAPPEPTEAAEPAEAGTQAEPAEPAEPTEPATPAEPAAPRLDEPTFEMRLPGPRTPAPAPGHDDAAPEPTPAAGPTPEPEPEPEPAPEPTPAPEPAPRLTDKGLPKRTPKVVQAGSAAARERKGGTDAAEALRRRLGGFQQGAIEGRRDVAAELEDSHQQADTDTGETVEEVRR
>CP032698.1|AYG80465.1|2917031_2917817_+|hypothetical-protein
MRIQLTTAPGDPARPNEDWAATALPASGLGGLLVVLDGVTPLPGNGDCVHDVPWYTARLGGALTELSASRRDLTLGEILAEAIRRTADAHRDTCDLSHPRTPQATVVLARWDAAELEYLVLSDSALLLEAADGTVRAVLDDRLDRVPRACLVSDAVADSLVRNKEGGFFTAAADPSVAALAVTGREPLARVRSVLALTDGASRWVEKFREGSWQDCLALVRKAGVEGLVERVRELEAADEERVFLGGSKRHDDATAVWVEV
>CP032698.1|AYG80466.1|2917849_2918290_-|putative-HTH-type-transcriptional-regulator
MHGSDQEFLALERELAVFLRRARASSGEMAREVHPDLEPAAYGLLVRLDEVGPQRATELAGYFGVGKATMSRQLHALEDLGLVAREPDPADGRAFLVRITEEGTARFGRVRDARRERYVRKLANWDRREISELARLLHQLNAAAES

Crispr_ID: CP032698_14

• CRISPR_ID: CP032698_14
• CRISPR_location: 2935976-2936146
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_14

Consensus_repeat	Method
ACGACGGCGGGTTTTCAGGGGCGCGGGGAACTGCGCGACCAGCCCCGCACGGCC	PILER-CR

spacers of CP032698_14

>14.1|2936030|14|CP032698|PILER-CR
CGCAGACGAAAACG
>14.2|2936098|20|CP032698|PILER-CR
GAAGCGACCCCGACCCGCAC

CRISPR arrays and Neighbor proteins around CP032698_14

CRISPR arrays

The CRISPR arrays of CP032698_14

>merge|CP032698|14|2935976-2936146|PILER-CR
ACGACGGCGGGTTTTGAGGGGCGCGAGGAACTGCGCGACCAGCCCCGCGCGGCCCGCAGACGAAAACGGGTTTTTCAGGGGCGCGGGGAACTGCGCGAGAAGCGACCCCGACCCGCACACGACGGCGGGTTTCAGGGGCGCGGGGAACTGCGCGACCAGCCCCGCACGGCC

>CP032698|14|4|2935976-2936146|PILER-CR
ACGACGGCGGGTTTTGAGGGGCGCGAGGAACTGCGCGACCAGCCCCGCGCGGCC	CGCAGACGAAAACG
GGTTTTTCAGGGGCGCGGGGAACTGCGCGAGAAGCGACCCCGACCCGCACACGA	CGGCGGGTTTCAGGGGCGCG
GGGAACTGCGCGACCAGCCCCGCACGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80471.1|2923764_2924715_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
CP032698.1|AYG80480.1|2934542_2935607_+|Transcriptional-regulator-YqjI	unknown	unknown	gnl|CDD|367559
CP032698.1|AYG80475.1|2927942_2931797_+|Multifunctional-2-oxoglutarate-metabolism-enzyme	unknown	unknown	gnl|CDD|237030
CP032698.1|AYG80487.1|2942160_2942928_+|Glutamine-transport-ATP-binding-protein-GlnQ	unknown	unknown	gnl|CDD|224051
CP032698.1|AYG80483.1|2937286_2938252_-|Alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176227
CP032698.1|AYG80479.1|2933473_2934541_+|hypothetical-protein	unknown	unknown	gnl|CDD|226123
CP032698.1|AYG80481.1|2936381_2936933_-|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpC1	unknown	unknown	gnl|CDD|274529
CP032698.1|AYG80490.1|2944412_2944838_-|hypothetical-protein	unknown	unknown	gnl|CDD|274282
CP032698.1|AYG80484.1|2938396_2939614_-|NAD-dependent-malic-enzyme	unknown	unknown	gnl|CDD|223358
CP032698.1|AYG80476.1|2931898_2932102_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80478.1|2932458_2933274_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80485.1|2940230_2941193_+|Glutamine-binding-periplasmic-protein	unknown	unknown	gnl|CDD|270225
CP032698.1|AYG80488.1|2943004_2943778_-|C-methyltransferase-CouO	unknown	unknown	gnl|CDD|379312
CP032698.1|AYG80489.1|2943879_2944494_+|hypothetical-protein	unknown	unknown	gnl|CDD|378696
CP032698.1|AYG80477.1|2932229_2932415_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80473.1|2925736_2926474_+|Alkaline-phosphatase-synthesis-transcriptional-regulatory-protein-PhoP	unknown	unknown	gnl|CDD|223816
CP032698.1|AYG80472.1|2924940_2925645_+|Polyamine-aminopropyltransferase	unknown	unknown	gnl|CDD|223498
CP032698.1|AYG80474.1|2926470_2927661_+|Alkaline-phosphatase-synthesis-sensor-protein-PhoR	unknown	unknown	gnl|CDD|223715
CP032698.1|AYG80486.1|2941220_2942156_+|L-cystine-transport-system-permease-protein-YecS	unknown	unknown	gnl|CDD|223836
CP032698.1|AYG80482.1|2936932_2937142_-|hypothetical-protein	unknown	unknown	gnl|CDD|234647

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80480.1|2934542_2935607_+|Transcriptional-regulator-YqjI	gnl|CDD|367559	pfam03551, PadR, Transcriptional regulator PadR-like family. Members of this family are transcriptional regulators that appear to be related to the pfam01047 family. This family includes PadR, a protein that is involved in negative regulation of phenolic acid metabolism.	1.67002e-21
CP032698.1|AYG80475.1|2927942_2931797_+|Multifunctional-2-oxoglutarate-metabolism-enzyme	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0
CP032698.1|AYG80487.1|2942160_2942928_+|Glutamine-transport-ATP-binding-protein-GlnQ	gnl|CDD|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	3.09714e-155
CP032698.1|AYG80483.1|2937286_2938252_-|Alcohol-dehydrogenase	gnl|CDD|176227	cd08266, Zn_ADH_like1, Alcohol dehydrogenases of the MDR family. This group contains proteins related to the zinc-dependent alcohol dehydrogenases. However, while the group has structural zinc site characteristic of these enzymes, it lacks the consensus site for a catalytic zinc. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H)-binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	4.96764e-99
CP032698.1|AYG80479.1|2933473_2934541_+|hypothetical-protein	gnl|CDD|226123	COG3595, COG3595, Uncharacterized conserved protein [Function unknown].	3.68757e-12
CP032698.1|AYG80481.1|2936381_2936933_-|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpC1	gnl|CDD|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	2.09044e-10
CP032698.1|AYG80490.1|2944412_2944838_-|hypothetical-protein	gnl|CDD|274282	TIGR02754, putative_signal_peptidase, nickel-type superoxide dismutase maturation protease. Members of this protein family are apparent proteases encoded adjacent to the genes for a nickel-type superoxide dismutase. This family belongs to the same larger family (see pfam00717) as signal peptidase I, an unusual serine protease suggested to have a Ser/Lys catalytic dyad. [Cellular processes, Detoxification, Protein fate, Protein modification and repair].	2.6025e-24
CP032698.1|AYG80484.1|2938396_2939614_-|NAD-dependent-malic-enzyme	gnl|CDD|223358	COG0281, SfcA, Malic enzyme [Energy production and conversion].	1.59631e-174
CP032698.1|AYG80471.1|2923764_2924715_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	1.74553e-06
CP032698.1|AYG80485.1|2940230_2941193_+|Glutamine-binding-periplasmic-protein	gnl|CDD|270225	cd01004, PBP2_MidA_like, Mimosine binding domain of ABC-type transporter MidA and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the periplasmic binding component of ABC transporter involved in uptake of mimosine MidA and its similar proteins. This periplasmic binding domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	9.28625e-73
CP032698.1|AYG80488.1|2943004_2943778_-|C-methyltransferase-CouO	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	4.00714e-19
CP032698.1|AYG80489.1|2943879_2944494_+|hypothetical-protein	gnl|CDD|378696	pfam11706, zf-CGNR, CGNR zinc finger. This family consists of a C-terminal zinc finger domain. It seems likely to be DNA-binding given the conservation of many positively charged residues. The domain is named after a highly conserved motif found in many members of the family.	6.3827e-13
CP032698.1|AYG80473.1|2925736_2926474_+|Alkaline-phosphatase-synthesis-transcriptional-regulatory-protein-PhoP	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.2839e-82
CP032698.1|AYG80472.1|2924940_2925645_+|Polyamine-aminopropyltransferase	gnl|CDD|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	2.36626e-13
CP032698.1|AYG80474.1|2926470_2927661_+|Alkaline-phosphatase-synthesis-sensor-protein-PhoR	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	9.07314e-48
CP032698.1|AYG80486.1|2941220_2942156_+|L-cystine-transport-system-permease-protein-YecS	gnl|CDD|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	3.08485e-84
CP032698.1|AYG80482.1|2936932_2937142_-|hypothetical-protein	gnl|CDD|234647	PRK00118, PRK00118, putative DNA-binding protein; Validated.	0.00047824

Protein sequences

>CP032698.1|AYG80480.1|2934542_2935607_+|Transcriptional-regulator-YqjI
MPPVFAHGRLRLYLLNLLDEAPRHGYEVIRLLEERFQGLYAPSAGTVYPRLAKLEAEGLVTHTTEGGRKVYSITDAGRAELAGRGGELADLELEIRDSVSELAAEIRDDVRGAAGSLREDMRRAAREARTGQASAGAGRGARKGFPEASDFFDNAWGDGEAWQQAKEEFKRAKQEWKEQARRAKDESRRARDEAQQARRQAKEAQEKAREEMQRVARDVQRQVQEHFARGDWPTGVREGLAEITKELGRFGFGPSTAPGSGPASEGGAAAADVTVERVDLGKPDAGGGTGPEWAREEPSGDPARDLDRLLDRFRDDIRDAARDHGVTSAQLAEARGHLAEAAVRIGSALRPPRA
>CP032698.1|AYG80479.1|2933473_2934541_+|hypothetical-protein
MSESTWAVPEPRKLTFDEHGGHGGPVTKLQVRIVNGTVNVVGTEESSARLEVSSVEGPPLIVTRDGSTLTVGYEDLPWRGFLKWLDRKGWNRSAVVSLAVPADADVEVGTVGAGSVVSGIRGRTEVRGVSGDTTLVKLAGPVRAESVTGNLEAQAVTGDLRFKSVSGDLTVVEGAGRCVAAESVSGDMLLDLDPGAQATDIRLTTVSGEVAIRLPHPADAQVEANTASGTVSSAFEDLRVSGQWGTKKITGTLGAGNGTLRATTVSGSIALLRRPTQEEPPAGAGGPGGSAGSGGSAGSGGSAGPDSSAGPDGAGAPDSWPGPDSWASATDSTGPDGSAGPDSSASSADPTKKVL
>CP032698.1|AYG80478.1|2932458_2933274_-|hypothetical-protein
MSVPDAAAGALLLCRAEPPMVRPVAHLLRERMLLASAGTGWSVIVPADKPWQAGAGPVDEVLAGWAGALAIGVGSPAIALWWDDSQAGYTLASGFRRTVGYVWLADGTPVGEGEAMRTFAARLGLDPVHDREALDALTLPDPAADARARLLGLLAVLARTGVALPAGLTPGEPTDRLRSVAAALGAEPIEWSGWRDAVRAELDAVEDSPLGPWVRGPKARLLGTAQLAAGLPLTAWGLARRSGGWTTAGAILVAHGVLGLVYDRMRARPTV
>CP032698.1|AYG80477.1|2932229_2932415_+|hypothetical-protein
MYFTDRGIEELEKRRGEEEVTFEWLAEQLRTFVDLNPDFEVPVERLATWLARLDDEDDDEE
>CP032698.1|AYG80476.1|2931898_2932102_-|hypothetical-protein
MFGGLDELFAPARRHTEEERRRQEITLDEVGDSDPGRGPIDLAGGSVVIRVPPPPQHPDRDADDSDG
>CP032698.1|AYG80475.1|2927942_2931797_+|Multifunctional-2-oxoglutarate-metabolism-enzyme
MSSQSPSNSSVSTDQDGQGKNPAAGFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKPGATGTADNPVQGAPTAAAAAGAAPAAAAPAAPAAPAQAVPAPAAAATTPAPAKAPAQAAAPAKAPAPAKPAAAAAPAAKPGASTGSTGAAAAAQPAGATEAPAGPEYVTLRGPAAAVAKNMNASLEMPTATSVRAVPVKLLFDNRIVINNHLKRARGGKVSFTHLIGYAMVQAIKAMPSMNYAFVEKDGKPTLVKPEHVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARNNKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRIVANLLLGDDGFYDDIFEALRIPYEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLEREFAVGGFAGKTLMKLRDVLGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERSHSKPEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGASGTFTGLDGEQIKVSLVANPSHLEAVDPVLEGVARAKQDVINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRVARLAFEFRQTFNKDVVIDLICYRRRGHNEGDNPQFTNPQMYNLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQLEKVFAEVREATSAPGEIHSSDHQAEFPVAVNTAVSQEAVKRIAESQVNIPERITVHPRLMPQMQRRASSVDDGTIDWGMGETLAIGSLLMEGVPVRLSGQDTRRGTFGQRHAVLVDQVTGEDYTPLMYLSEDQARYNVYDSLLSEYAAMGFEYGYSLARPESLVMWEAQFGDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKAEEFTSGGFRPVIGDEHVDANAVRKVVFCAGKVYYDLAAERDKRGAKDTAIIRIERLYPLPGAELQAEIAKFPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSKKRHEQEQEQLVNEVFEA
>CP032698.1|AYG80474.1|2926470_2927661_+|Alkaline-phosphatase-synthesis-sensor-protein-PhoR
MSRAGDRARQLRGSGERPGWDEPGRRGDWARATRGLRGRIAAGLRSVSISIKTKLGTLVVVSVFITTGLLMVALQTRTELRFITVFSVIATLLITQFVAHGLTAPLDEMNTVARAISHGDYTRRVRGADRRDELGDLAGTINRMADDLEAVDRHRKELVANVSHELRTPIAALRAVLENVVDGVSAADPETMRTALKQTERLGRLVETLLDLSRLDNGVVTLRAQRFEVWPYLSGVLKEANLAAAQRGLSSGSGNHQRTDVHLHLDVSPPELTAHADAERLHQVVANLIDNAVKHSPPHGRVTVRARRGPQPESLDLEVLDEGPGIPQSEWHRVFERFNRGTAPSPHGPGSDGGTGLGLAIARWAVDLHGGRIGVAESARGCRIQVTLPGIPRQQS
>CP032698.1|AYG80473.1|2925736_2926474_+|Alkaline-phosphatase-synthesis-transcriptional-regulatory-protein-PhoP
MEQTHTGHNGVAATPGAQRRVLVVEDDTTIVDAIAARLRAEGFQVQTALDGPAAVDTAEAWQPDLMVLDIMLPGFDGLEVCRRVQARRPVPVLMLTARDDETDMLVGLGVGADDYMTKPFSMRELAARVHVLLRRVERAALAATTPRTGILRLGELEIDHAQRRVRVRGEDVHLTPTEFDLLSCLANTPRAVLSREQLLAEVWDWADASGTRTVDSHIKALRRKIGAERIRTVHGVGYALETPAP
>CP032698.1|AYG80472.1|2924940_2925645_+|Polyamine-aminopropyltransferase
MRGAAGDGILTVMNDIATLDRRQGPHGEVVLRQRGAHYEIIANGCFLMDTSDGRSERLLVDAAYATLSPGTTRPSLLIGGLGVGFSLVHAAQDPRWGQIAVVEREQAIIDWHGTGPLGAISGPALSDSRTRIIQADLVDYVRTAQETYDALCLDIDNGPEWTVTEGNGGLYSPAGLAHCARRLRPGGVLAVWSAQPSPAFEQALRNAGFTGVHTEEIRVARGVPDVVHLGVRPA
>CP032698.1|AYG80471.1|2923764_2924715_-|hypothetical-protein
MHPLETHPPAGPAPTPPLDVIPPRRPGVIPSDGPAPGAPQPGRPGPAPTGGSAPGAPPGPGAPDALGSAPPAGPDSGPARAPAPVPVSVPGGAAAAPALLPESVPGVRAALLGAGRLLPSPRSTPFAFGYVVLLLATSLYGEYGDPETVSALLRGSSTDVAHLSTTPVLTIFASALWIAGGMASPYALVFLFVLAALERRIGGWRTAGVFLLGHVVATLATEGPVALSVLAGHLPESSLHRLDYGISFGLMATVGALAGLLTPFLRWTALAVVGVLLVQDLLDMAEPLAAWGHPVALLVGVACWPAARRVRVTPYP
>CP032698.1|AYG80481.1|2936381_2936933_-|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpC1
MFERFTVHARGVVTGAVEHASRAGSPVVTEEHLLLALLDREGTKAAFALASLGVTDRRAELIEALAAARRRGGLSKADTAALSELGISVEEIVARVEQTHGPGALADAPRGKAWPSGRPSFTKESKKVLERALRIALARKQKHIGDEHLLLAVAAGVGVVGEVLAEFGGTYGGVEGVLSLRAA
>CP032698.1|AYG80482.1|2936932_2937142_-|hypothetical-protein
MTEATDLAARAGDRDPRIGLRAVAALRRLLEQLESVQVRSARNQGWSWQEIATELGISRQAVHKKHGRN
>CP032698.1|AYG80483.1|2937286_2938252_-|Alcohol-dehydrogenase
MFAAYAARIDRDQPLSGLELGERPAPEVRPGWSLIDVRAASLNHHDVWSLRGVGITEDKLPMILGCDAAGVDQDGNEVVLHSVIGQSGHGVGPTEGRSILTEKYQGTFAEQVAVPTWNVLPKPKGMSFAEAACLPTAWLTAYRMLFTNAGVRPGDSVLVQGAGGGVATAAIVLGKAAGLRVFATSRDEHKRRRAVELGAVEAYESGARLPERVDAVIETVGAATWSHSVKSLRPGGTLVISGATSGDRPAHAELTRIFFLELKVVGSTMGTKDELEDLLAFCSATGVRPVIDEVLPLDRAREGFEKVAAGDVFGKVVLTTG
>CP032698.1|AYG80484.1|2938396_2939614_-|NAD-dependent-malic-enzyme
MAAEIVNPRSDSSPEAYGDSVDAFDPAFALHRGGKMAVQATVPIRDKDDLSLAYTPGVAKVCSAIAENPELVHDYTWKSQVVAVVTDGTAVLGLGDIGPEASLPVMEGKAILFKQFGGVDAVPIALATTDTDEIIETVVRLAPSFGGVNLEDISAPRCFEIERRLQEALDIPVFHDDQHGTAVVTLAALRNAAKLTGRTLGDLRAVISGAGAAGVAIAKFLLEAGLGDVAVADRKGIVSSDRTDLTDVKRELAELTNKAGLSGSLETALAGADVFIGVSGGTVPEPAVASMAPGAFVFAMANPNPEVHPDIAHKYASVVATGRSDYPNQINNVLAFPGIFAGALQVRASRITEGMKIAAANALADVVGDQLAADYVIPSPFDERVAPAVTAAVAAAARAEGVARR
>CP032698.1|AYG80485.1|2940230_2941193_+|Glutamine-binding-periplasmic-protein
MTASTTRRTTASKSRIAAVGAIAVAGALLVTGCGDQTKKGSAPESSGGASKSAPLFSKLPANIQKAGVIKIGTDATYAPMEFKEGEKIVGIDPDIAAALGKQLGVKFEFTSGTFDTLLGALPTGRYDAVMSSVSDTKARQEGLDKDGKKTGTGVDFVDYYTASTGILVKKGNPEGIKSTEDLCGKKIAVQRGTTYEQAAKDLAAKCKTDGKGELAFEPYATDAEAQTRVKAGGAVADLNDSPVAAYIAKTAGGGADFEAVANKSDAGPFGIAVDKKNTQLRDALSAALDAIIADGTYKTAIDKWGGAQGAVTKAAINGGS
>CP032698.1|AYG80486.1|2941220_2942156_+|L-cystine-transport-system-permease-protein-YecS
MTDKLDKTPSGPADAAPEQVPPDVIRAIPVRHYGRWISAVVVVAVLGALGYAFAQGNVRWATVTDKLFDPSILTGLWHTVLISVVSMAVGLILGVLFAVMRLSKNPVTSSVAWLYIWFFRGTPVYVQLLIWFNLALIFPILNLGFYKDYMTAVMTPFLAALLGLGLNEGAYMAEIVRAGIQSVDEGQTEASHALGMTQMQTMRRVVLPQSMRVIIPPTGNEFINMLKTSSLVVAVQYQDLLRSAQDVAATSFAVMEMLFVASIWYLALTSVFSVGQYYLERRFARGSLRALPPTPLERIKSNLLSLSQWRR
>CP032698.1|AYG80487.1|2942160_2942928_+|Glutamine-transport-ATP-binding-protein-GlnQ
MTAQPMVKAEGVHKSFGPAHILKGIDLEVAEGEVFCLIGPSGSGKSTFLRCINHLEQINAGRLYVDGDLVGYRQKGDKLYELKDSEVALKRRDIGMVFQRFNLFPHMTAVENVMEAPVQVKRESKAVARERALKLLDRVGLADKAGNYPSQLSGGQQQRVAIARALAMQPKLMLFDEPTSALDPELVGDVLDVMRGLAEDGMTMIVVTHEMGFAREVGDSLVFMDDGVVVEAGNPRDVLTNPQHDRTKSFLSKVL
>CP032698.1|AYG80488.1|2943004_2943778_-|C-methyltransferase-CouO
MAETVAGAGTSTDWRGWQDSWDRQQEWYMPDREERFRVMLDMVEACVGPAPRVLDLACGTGSITDRLLKRFPEAVSTGVDLDPALLAIAEGTFAGDDRVTFVTADLKDPHWVRSLPYDSYDAVLTATALHWLHSEPLAALYGQIAQLVRDGGVFMNADHMIDPTTPRINAAERAHRHAQMDRAKAGGALDWAEWWALAAKDPALAAPTAKRYEIYGEHADGDMPAAAWHAETLRAAGFAEARPVWASPSDTLLLALK
>CP032698.1|AYG80489.1|2943879_2944494_+|hypothetical-protein
MELAYYSDYAVRLVNTEEPARNKDALTSVDAVRELFGGNKSAARRATDADVTRFRSVRARLRAVFEAADRGEEVQAVDLLNSLLLEFPVSPQVSGHEHRDEDDRPLWHMHLADHPSNATAGYAAIASMGLAFHLTEYGVDRLGLCQAAPCRNAYLDTSTNRSRRYCSDRCATRANVAAYRARKRLETDRSESTGRTEASAQDAT
>CP032698.1|AYG80490.1|2944412_2944838_-|hypothetical-protein
MTDEGREPSALLGIAEVLGTSMVPTLLHGDQLLVHYGAELRAGDVAVLRHPLQQDLLIVKRLMELREGGWWVLGDNTDDEAVDSRAFGAVPVDLVLGRVRGRFRPMTAGRRRTLGYVASWALASVRPVLSDRSVSRRLRAR

Crispr_ID: CP032698_15

• CRISPR_ID: CP032698_15
• CRISPR_location: 3086357-3086437
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_15

Consensus_repeat	Method
TTGCGCAGTTCCCCGCGCCCCCA	CRISPRCasFinder

spacers of CP032698_15

>15.1|3086380|35|CP032698|CRISPRCasFinder
CAACCCGTTCTCGCCTGCGGACCGTGCGTGGCTGG

CRISPR arrays and Neighbor proteins around CP032698_15

CRISPR arrays

The CRISPR arrays of CP032698_15

>merge|CP032698|15|3086357-3086437|CRISPRCasFinder
TTGCGCAGTTCCCCGCGCCCCCACAACCCGTTCTCGCCTGCGGACCGTGCGTGGCTGGTCGCGCAGTTCCCCGCGCCCCCA

>CP032698|15|12|3086357-3086437|CRISPRCasFinder
TTGCGCAGTTCCCCGCGCCCCCA	CAACCCGTTCTCGCCTGCGGACCGTGCGTGGCTGG
TCGCGCAGTTCCCCGCGCCCCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80619.1|3092989_3093574_-|hypothetical-protein	unknown	unknown	gnl|CDD|377450
CP032698.1|AYG80607.1|3080756_3080984_+|hypothetical-protein	unknown	unknown	gnl|CDD|378634
CP032698.1|AYG80609.1|3081753_3082605_-|hypothetical-protein	unknown	unknown	gnl|CDD|205967
CP032698.1|AYG80616.1|3089013_3089889_-|5'-3'-exoribonuclease	unknown	unknown	gnl|CDD|223686
CP032698.1|AYG80614.1|3088234_3088840_-|hypothetical-protein	unknown	unknown	gnl|CDD|225006
CP032698.1|AYG80618.1|3090945_3092187_+|Multidrug-efflux-protein-YfmO	unknown	unknown	gnl|CDD|341027
CP032698.1|AYG80606.1|3079973_3080615_+|putative-HTH-type-transcriptional-regulator-TtgW	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG80621.1|3095224_3096127_-|hypothetical-protein	unknown	unknown	gnl|CDD|223769
CP032698.1|AYG80605.1|3079607_3079829_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80620.1|3094059_3095184_+|Cobalt/magnesium-transport-protein-CorA	unknown	unknown	gnl|CDD|213364
CP032698.1|AYG80612.1|3086761_3087688_-|hypothetical-protein	unknown	unknown	gnl|CDD|224349
CP032698.1|AYG80617.1|3090107_3090746_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80610.1|3082963_3085345_+|ATP-dependent-RNA-helicase-CshA	unknown	unknown	gnl|CDD|223587
CP032698.1|AYG80603.1|3077216_3078467_-|hypothetical-protein	unknown	unknown	gnl|CDD|371483
CP032698.1|AYG80613.1|3087965_3088118_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80611.1|3085444_3086317_+|Epoxide-hydrolase-B	unknown	unknown	gnl|CDD|223669
CP032698.1|AYG80602.1|3075130_3076861_-|Periplasmic-oligopeptide-binding-protein	unknown	unknown	gnl|CDD|173871
CP032698.1|AYG80604.1|3078475_3079471_-|Lipase-1	unknown	unknown	gnl|CDD|184875
CP032698.1|AYG80615.1|3088867_3089086_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80608.1|3081197_3081461_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80607.1|3080756_3080984_+|hypothetical-protein	gnl|CDD|378634	pfam11305, DUF3107, Protein of unknown function (DUF3107). Some members in this family of proteins are annotated as ATP-binding proteins however this cannot be confirmed. Currently no function is known.	2.45243e-37
CP032698.1|AYG80609.1|3081753_3082605_-|hypothetical-protein	gnl|CDD|205967	pfam13794, MiaE_2, tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like.	2.0644e-90
CP032698.1|AYG80619.1|3092989_3093574_-|hypothetical-protein	gnl|CDD|377450	pfam05076, SUFU, Suppressor of fused protein (SUFU). SUFU, encoding the human orthologue of Drosophila suppressor of fused, appears to have a conserved role in the repression of Hedgehog signaling. SUFU exerts its repressor role by physically interacting with GLI proteins in both the cytoplasm and the nucleus. SUFU has been found to be a tumor-suppressor gene that predisposes individuals to medulloblastoma by modulating the SHH signaling pathway. Genomic contextual analysis of bacterial SUFU versions revealed that they are immunity proteins against diverse nuclease toxins in polymorphic toxin systems.	2.81732e-27
CP032698.1|AYG80603.1|3077216_3078467_-|hypothetical-protein	gnl|CDD|371483	pfam11350, DUF3152, Protein of unknown function (DUF3152). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	1.32653e-64
CP032698.1|AYG80618.1|3090945_3092187_+|Multidrug-efflux-protein-YfmO	gnl|CDD|341027	cd17474, MFS_YfmO_like, Bacillus subtilis multidrug efflux protein YfmO and similar transporters of the Major Facilitator Superfamily. This family is composed of Bacillus subtilis multidrug efflux protein YfmO, bacillibactin exporter YmfD/YmfE, uncharacterized MFS-type transporter YvmA, and similar proteins. YfmO acts to efflux copper or a copper complex, and could contribute to copper resistance. YmfD/YmfE is involved in secretion of bacillibactin. The YfmO-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.01332e-94
CP032698.1|AYG80606.1|3079973_3080615_+|putative-HTH-type-transcriptional-regulator-TtgW	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.12962e-15
CP032698.1|AYG80621.1|3095224_3096127_-|hypothetical-protein	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	8.09294e-09
CP032698.1|AYG80616.1|3089013_3089889_-|5'-3'-exoribonuclease	gnl|CDD|223686	COG0613, COG0613, Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only].	3.75595e-47
CP032698.1|AYG80620.1|3094059_3095184_+|Cobalt/magnesium-transport-protein-CorA	gnl|CDD|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	8.93001e-171
CP032698.1|AYG80612.1|3086761_3087688_-|hypothetical-protein	gnl|CDD|224349	COG1432, COG1432, Uncharacterized conserved protein [Function unknown].	7.39628e-06
CP032698.1|AYG80610.1|3082963_3085345_+|ATP-dependent-RNA-helicase-CshA	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	3.43293e-138
CP032698.1|AYG80614.1|3088234_3088840_-|hypothetical-protein	gnl|CDD|225006	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion].	1.25699e-39
CP032698.1|AYG80611.1|3085444_3086317_+|Epoxide-hydrolase-B	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.92353e-19
CP032698.1|AYG80602.1|3075130_3076861_-|Periplasmic-oligopeptide-binding-protein	gnl|CDD|173871	cd08506, PBP2_clavulanate_OppA2, The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold. Clavulanic acid (CA), a clinically important beta-lactamase inhibitor, is one of a family of clavams produced as secondary metabolites by fermentation of Streptomyces clavuligeru. The biosynthesis of CA proceeds via multiple steps from the precursors, glyceraldehyde-3-phosphate and arginine. CA possesses a characteristic (3R,5R) stereochemistry essential for reaction with penicillin-binding proteins and beta-lactamases. Two genes (oppA1 and oppA2) in the clavulanic acid gene cluster encode oligopeptide-binding proteins that are required for CA biosynthesis. OppA1/2 is involved in the binding and transport of peptides across the cell membrane of Streptomyces clavuligerus. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	4.13995e-180
CP032698.1|AYG80604.1|3078475_3079471_-|Lipase-1	gnl|CDD|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	2.95136e-27

Protein sequences

>CP032698.1|AYG80611.1|3085444_3086317_+|Epoxide-hydrolase-B
MSKPRSLDLPARTRAYRLRTARQEFAVLDSRPEGRALGTVLLVPGYTGSKEDFLALLDPLADAGYRAVAVDGRGQFESPGPRRTSAYTPRQLGGDVLAQVAALGDGPVHLVGHSFGGFVARSAARLDPSAFRSLTLLSSGPGRVGPDQRTKIRLLRAALPVLPPSWVWAATVWLDGRDPAYVSDPPEIVEFLQRRWFSTQPAQLIATGRQLRVEPDRTEGLARLPLPLHVAYGEGEMVWTVGELAHMARSVGARHTVIAGAEHSPNVSHPAELASALSAFWSTTPTPPHP
>CP032698.1|AYG80610.1|3082963_3085345_+|ATP-dependent-RNA-helicase-CshA
MSPFPIQEMTLPVALSGSDIIGQAKTGTGKTLGFGLPILERVIVPADVEAGRATSDQLTNTPQALVVVPTRELCQQVTNDLLTAGKVRNVRVLAIYGGRAYEPQVEALKKGVDVIVGTPGRLLDLAGQKKVDLSHVKVLVLDEADEMLDLGFLPDVEKIIQLLPPKRQTMLFSATMPGAVIGLARRYMSQPTHIRATSPDGEGTTVANTEQFVYRAHSMDKPEMVARILQAEGRGLAMIFCRTKRTAADIAEQLAKRGFASGAVHGDLGQGAREQALRAFRNGKVDVLVCTDVAARGIDVDGVTHVINYQSPEEEKTYLHRIGRTGRAGKKGIAITLVDWDDIPRWQLINKALDLKFPDPPETYSTSPHLFEELRIPKGTKGVLPRGERTRAGLAAEEVEDLGETGGRGRKSAAAAPVVTEERPPRTRTPRQRRRTRGGSQDGVETPAAAPAPAPVAEAPVTEATEQVTEARTPRRRRRTRVGAPSNAPQAAAAPVIEAASAAPVAEPVTKAEPRRRTASAAPAVTPEPVKAEPRRRPAPAATVAVPEPAKAEPRRRRVRKVVDTSSEVGFMTPESAALELARAAKAKTTAAMTEVASAPAAAVTAAPVTAAPEKPRRTRAKKAAEAVVETVEAPAAVETEAPAKPRRTRAKKVAEAAPETVVEAAAEAEAPAKPRRTRAKKAAEAVVETVEAPATVETEAPAKPRRTRAKKAAEAAPEATEAPAAPRRTRAKKVAEAAPETVVEAAAEAEAPAKPRRTRAKKAAVAPEAVEAEAPAKPRRTRAKKAAVAPEA
>CP032698.1|AYG80609.1|3081753_3082605_-|hypothetical-protein
MCVGRIRGTGDSGVRKQALTAHPGRAIVRLMETSDNATAAEGTTPEPERTGIAAQDWATASAVPQYRAAVVDLLGALAYGELAAFERLADDAKLAPTLADKAELAKMASAEFHHFERLRDRLAQVDAEPTAAMEPFAKALDDFHQQTAPSDWLEGLVKAYVGDSIASDFYREVANHLDTDTRSLVLAVLDDTGHGNFAVEKVRAAIEADPRVGGRLALWARRLMGEALSQAQRVVAERDALSTMLVGGVDGVAAGFDLAAVGEMFTRITKAHTKRMAALGLAA
>CP032698.1|AYG80608.1|3081197_3081461_+|hypothetical-protein
MLLEAIGSVLLGFALAWAAAARLAHRLPDRRTVLGVGPLAGLFGAFLTHSAIGPGHGVTTVLGAAFVASVTLSLLLRPTRRLRRWAA
>CP032698.1|AYG80607.1|3080756_3080984_+|hypothetical-protein
MEVKIGVQHAPREIVLESGQSAEEVESAVADALAGKAQLLSLTDDKGRKVLVPADKIAYVEIGEPAVRRVGFGAL
>CP032698.1|AYG80606.1|3079973_3080615_+|putative-HTH-type-transcriptional-regulator-TtgW
MTAIEQTEAARPRGTRLPRRARRNQLLGAAQEVFVAQGYHAAAMDDIAERAGVSKPVLYQHFPGKLDLYLALLDQHCESLLHAVRTALASTSDNKLRVAATMDAYFAYVEDEGGAFRLVFESDLTNEPAVRERVDRVSLQCAEAISDVIAEDTGLSKDESMLLAVGLGGVSQVVARYWLSSESTIPRDKAVQLLTSLAWRGIAGFPLHATEGH
>CP032698.1|AYG80605.1|3079607_3079829_+|hypothetical-protein
MSVDPSDPETFQEAEEGTPRVPDETNEADAAEQHTDVRQDRDEPLSHVDPGTANEADAVEQTRVVSLDEDDYR
>CP032698.1|AYG80604.1|3078475_3079471_-|Lipase-1
MSSTELPETPAAAALAPRVSPVGAAEGEELRRVSLPGLTLAVRSRPGTRAGLDPALYVHGFGGSSRNWSALMALLADRVDGEALDLPGFGDSPPPDDGAYTVTAQARAVIRLLDSTGRGPVHLIANSLGGAVCTRVAAVRPDLVRTLTLVSPALPEIRVQRGAWPTALIAVPGVASLFAKMTRDWTAEDRTRSALALSYGDPARITPEGLESAVRELERRLQLPYFWDAMVRSARGIVDAYTLGGQHGLWRQAERVLAPTLLVYGTRDRLVSYRMARRAAAAYRDSRLLTLPDAGHVAMMEYPDTVARAVRELIDDTSGGRHRGDDRENRS
>CP032698.1|AYG80603.1|3077216_3078467_-|hypothetical-protein
MGRHSRPKATGAEGPIPQARAPRAPEAGQAATPGGGRRRRPAQGDGPETHHGAGTPAFGTPQVRGGHPQHREDGPGAGYVGRHGAGYGTPRPAQQSPNGTAPRIPGPRRSSIEAFDGPGPARTDTPRTVAVPAPARPEPAAPAPETKPKASKGRTFTGIAAAAVTTVLAVVVAGQVTSDGDKHDVAGRTAGDKHRDDDGSASRGSGRSTPQAAPAVLTYDQKMAQQFPLDAGLTASGTFETVPGAAGAPGKGTKYRYRVDVEKGLALDGGLFADAVQKTLNDDRSWAHAGKMTFERISSGKPDFVITLASPGTTGAWCAKSGLDTTEDNVSCDSAATDRVMINAYRWAQGSVTFGPKAMLAYRQMLINHEVGHRLGHDHESCRTPGAPAPVMQQQTKSLDLKGIKCLPNPWVYPGS
>CP032698.1|AYG80602.1|3075130_3076861_-|Periplasmic-oligopeptide-binding-protein
MRHTSISSGNVARAAAIAVVLAMGAVACGPEGGDAENAGAGASGTPHEGGTLSVLNNEAQTTFDPARLYTSGGGNVPSLVFRTLTTRKRANGAEGTKVVPDLATDTGRPNADATVWTYTLKDGLKYEDGSPITTADIKYGIERSFAAELSGGAPYLRDWLVGGAQYQGPYKDGGKQLASIETPDAKTIVFHLNKPEGEFPFLATQTQFAPVPKARDNGTKYAEHPVSSGPYKVVKNENDGEHLVLERNPNWSEATDPERKAYPDSIDVRSGLDQAVINQRLSASQGPDAAAVTTDTNLGPAELAKVGSDKRLAARVGTGHFGYTNYIAFNPNVKPFDDPKVRQAIAYAVDRTSVVNAVGGSSLAEPATTFLPNQKAFGYTPYDLFPAGESGNAAKAKELLKEAGHADGLTVTLTHSNAKGGPKGPEVATALQDALKKAGITVKLQGLEGNDYNDTVASAKKEPGFFLRGWGADWPSGGPFLAPIFDGRQIVRDGANFNTGFLNDASVNSEIDEINKLTDLTAAAPRWGALDKRIGEQAVVVPLFHPVYKRLVGKDVKNVVISDWTGVLDISQVAVK
>CP032698.1|AYG80612.1|3086761_3087688_-|hypothetical-protein
MDDSQEPQPARAPHDPVAQLDRKLDATNELLQRMLAEVAKTPSTHAIFVDAGYVYAAAGLLVTGTEDRRSFDLDAEGLIDAFIDKARTIFADSRLLRVYWYDGARRRIHTPEQQSIAELPDVKVRLGNLNANNQQKGVDSLIRSDLESLARHRAISDAALIGGDEDLVSAVEAAQGYGARVHLWGIEAAEGRNQAEPLLWEVDSQRTFDLDFCKPYVTRRPVTLYEDGPAPSREDVRFVGARIAATWLSERGRAALADLLPGHPYLPGPVDQDLLIEAERLLQRSLRGHADLRRALRDGFWQHLQSQY
>CP032698.1|AYG80613.1|3087965_3088118_+|hypothetical-protein
MRFEIMRLDDVDGIAVDSTVVDAASVNRIVQQAAAMGQRIYIRPTESAAS
>CP032698.1|AYG80614.1|3088234_3088840_-|hypothetical-protein
MFDAAVFGSLFLTLFVIMDPPGITPIFLALTAGRAAKVQRRMAWQAAAVALGVITLFGLVGHQILTYLHIDVPALMIAGGLLLLLIALDLLTGKTDEPQQTKDVNVALVPLGMPLLAGPGAIVQVILAVQNHDSVAGQVSVWAAIIAIHVVLYVTMRYSLLIIRVIKDGGVVLVTRLAGMMLSALAVQQIINGITQVIHAY
>CP032698.1|AYG80615.1|3088867_3089086_+|hypothetical-protein
MRGGRDAVARAGRARPPGRARKVVRAGCEERGYGDGVPGVRRGGLSLPGYGQVVPPAPGTGKAPVARRVISP
>CP032698.1|AYG80616.1|3089013_3089889_-|5'-3'-exoribonuclease
MRIDLHTHSTASDGTDTPAELVRNAAAAGLDVIALTDHDTTRGYAEAIAALPGLDRDLTLVTGAELSCRLDGVGLHMLAYLFDPEEPELARERELVRDDRVPRAQGMVTKLQELGVPVTWEQVARIAGDGSIGRPHVAEALVELGVVDSVSDAFVPEWLADGGRAYVGKHELDPFEAIRLVKAAGGVTVFAHPLAVKRGQVVPESAIAELAAAGLDGIEVDHTDHDAPTRDRLRALARDLGLLATGSSDYHGSRKTVRLGEWTTDPEIYGEITRRATGAFPVPGAGGTTCP
>CP032698.1|AYG80617.1|3090107_3090746_-|hypothetical-protein
MRGEPSCPKCGGRVRAPGLFADTWQCDAHGPVYPLQPVVPPSVEALEVVVRRAQVPVWMPWPLPVGWLFTGVAYAGDDRSGGRATAVACSGPGPLGGLGELILVAEELGVGLGARYAGIEGPDPGPFMSVDKPPHTKVLAAGRPTPLWHVTRTPDDRAVFAGEARGLWLWAIVWPEQSGLLMYDELVLTDLRDAGAEVELLPCGALTPRILS
>CP032698.1|AYG80618.1|3090945_3092187_+|Multidrug-efflux-protein-YfmO
MRQGTDPLDDGAGTGGLLRQPKAVWATAGASVVAFMGIGLVDPILPSIAKGLDATPSQVSLLFTSYFLITAVAMLVTGFVSSRIGGKKTLLAGLALVVVFAALAGTSNSVGELVGFRAGWGLGNALFVSTALAVIVGAAAGGSAAAILLYESALGLGMACGPLLGAVLGDMKWRYPFFGTAALMAIGFLAITVFLKEQPKPARKTSLLDPLKALGHGGLASAAASAFFYNYAFFTVLAFTPFVLNMSPYKSGGVFFAWGVLLAVFSVLVAPRLQERFGSLKVLGGSLVLLAADLIVLGYGNHTTAVAATVASGAFIGLNNTVYTELALGVSDAPRPVASAGYNFVRWFAAAAAPYFAPKIEEWSDLHIPFVVAAGAAVVGAGIVWVRRGVLTREVAGLRPGHAVEDGVSVFAN
>CP032698.1|AYG80619.1|3092989_3093574_-|hypothetical-protein
MVDVLALVEARLRTALGEPDARAAVTFLGTDRIEVLRFTDGDIVRYATLGMSAQPMADPTAALADPVKGPRAELVLSVRAGLADTDKVLRPLAVLAASPQVEGVVVAPGASLDLGEPLWPGAAFGSVLVAEPGGLIEDLELDAPMDPVRFLPLLPMTANEAAWKRVRGAAELEGRWLARGTDLRDPLRPSVPLD
>CP032698.1|AYG80620.1|3094059_3095184_+|Cobalt/magnesium-transport-protein-CorA
MSMIRDLRAVVRPALRKTSTPYNGYDTTRDPSASSAVVDCAVYRDGRRVQSVEETSCLTPREAMRRVREGGGFVWIGLHEPTEAEFAGIAAEFGLHPLAVEDAVHAHQRPKLERYDDTLFTVFKTIHYVEHAELTATSEVVETGEVMCFTGPDFVITVRHGGQGSLRALRKRLQDDPELLSKGPSAVLHAIADQVVDGYLAVVDAVQDDIDEVEIEVFSAPAKGSPRGVDAGRIYQLKREVLEFKRAVSPLLRPMQLLSERPMRLVDPDIQKYFRDVADHLARVQEQVVGFDELLNSILQANLAQASVAQNEDMRKITSWAAIIAVPTMVCGVYGMNFDHMPELHWKYGYPISMGLVAVACFAIHRTLKRNGWL
>CP032698.1|AYG80621.1|3095224_3096127_-|hypothetical-protein
MTTATTPAQNVAAVPRVDIVLLGVALASVSLSAPLIAATAAPALAIAFWRNALAVGVLTPVAWFKHRARLRALTRREVGLTVGAGALLALHFGLWLPSLSMTSVASSTALCTTTPIWTTLALRLRGHRPPALVWSGTLAACVGVVLLTGVDLTLSPRALAGDALALGGGIAAAGYVLLGAEVRKSVATVPYTYLCYGTAAAGLLAATLVSGADLTSYDAGTWAKLGLLTLAAQLLGHSLLNRVVASLGPSVTSTAILLETPGAALIAALWLGQEPPVLAYPALAVILAGLALVVRAGRGA

Crispr_ID: CP032698_16

• CRISPR_ID: CP032698_16
• CRISPR_location: 3086503-3086742
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP032698_16

Consensus_repeat	Method
ACCCCCCAAGGGGCGCGGGGAACTGCGCGAGCAAGC	CRT

spacers of CP032698_16

>16.1|3086539|32|CP032698|CRT
CCCGACAGCCCGCACCCGACCAACCGACAGGC
>16.2|3086607|32|CP032698|CRT
GTCGGCAGCCCGCGGACAACCACACACCGCCA
>16.3|3086675|32|CP032698|CRT
ACCGACGGCCCGCACCCGAACAACCGGCACGC

CRISPR arrays and Neighbor proteins around CP032698_16

CRISPR arrays

The CRISPR arrays of CP032698_16

>merge|CP032698|16|3086503-3086742|CRT
ACCCCCCAAGGGGCGCGAGGAACTGCGCGAGCAAGCCCCGACAGCCCGCACCCGACCAACCGACAGGCACCACCCCAGGGGCGCGGGGAACGGCGCGACCAGCCGTCGGCAGCCCGCGGACAACCACACACCGCCACCACCCCAAGGGGCGCGGGGAACTGCGCGAGCAAGCACCGACGGCCCGCACCCGAACAACCGGCACGCACCCCCCAAGGGGCGCGGGGAACTGCGCGAGCCAGG

>CP032698|16|1|3086503-3086742|CRT
ACCCCCCAAGGGGCGCGAGGAACTGCGCGAGCAAGC	CCCGACAGCCCGCACCCGACCAACCGACAGGC
ACCACCCCAGGGGCGCGGGGAACGGCGCGACCAGCC	GTCGGCAGCCCGCGGACAACCACACACCGCCA
CCACCCCAAGGGGCGCGGGGAACTGCGCGAGCAAGC	ACCGACGGCCCGCACCCGAACAACCGGCACGC
ACCCCCCAAGGGGCGCGGGGAACTGCGCGAGCCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80619.1|3092989_3093574_-|hypothetical-protein	unknown	unknown	gnl|CDD|377450
CP032698.1|AYG80607.1|3080756_3080984_+|hypothetical-protein	unknown	unknown	gnl|CDD|378634
CP032698.1|AYG80609.1|3081753_3082605_-|hypothetical-protein	unknown	unknown	gnl|CDD|205967
CP032698.1|AYG80616.1|3089013_3089889_-|5'-3'-exoribonuclease	unknown	unknown	gnl|CDD|223686
CP032698.1|AYG80614.1|3088234_3088840_-|hypothetical-protein	unknown	unknown	gnl|CDD|225006
CP032698.1|AYG80618.1|3090945_3092187_+|Multidrug-efflux-protein-YfmO	unknown	unknown	gnl|CDD|341027
CP032698.1|AYG80606.1|3079973_3080615_+|putative-HTH-type-transcriptional-regulator-TtgW	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG80621.1|3095224_3096127_-|hypothetical-protein	unknown	unknown	gnl|CDD|223769
CP032698.1|AYG80605.1|3079607_3079829_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80620.1|3094059_3095184_+|Cobalt/magnesium-transport-protein-CorA	unknown	unknown	gnl|CDD|213364
CP032698.1|AYG80612.1|3086761_3087688_-|hypothetical-protein	unknown	unknown	gnl|CDD|224349
CP032698.1|AYG80617.1|3090107_3090746_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80610.1|3082963_3085345_+|ATP-dependent-RNA-helicase-CshA	unknown	unknown	gnl|CDD|223587
CP032698.1|AYG80603.1|3077216_3078467_-|hypothetical-protein	unknown	unknown	gnl|CDD|371483
CP032698.1|AYG80613.1|3087965_3088118_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80611.1|3085444_3086317_+|Epoxide-hydrolase-B	unknown	unknown	gnl|CDD|223669
CP032698.1|AYG80602.1|3075130_3076861_-|Periplasmic-oligopeptide-binding-protein	unknown	unknown	gnl|CDD|173871
CP032698.1|AYG80604.1|3078475_3079471_-|Lipase-1	unknown	unknown	gnl|CDD|184875
CP032698.1|AYG80615.1|3088867_3089086_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80608.1|3081197_3081461_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80607.1|3080756_3080984_+|hypothetical-protein	gnl|CDD|378634	pfam11305, DUF3107, Protein of unknown function (DUF3107). Some members in this family of proteins are annotated as ATP-binding proteins however this cannot be confirmed. Currently no function is known.	2.45243e-37
CP032698.1|AYG80609.1|3081753_3082605_-|hypothetical-protein	gnl|CDD|205967	pfam13794, MiaE_2, tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like.	2.0644e-90
CP032698.1|AYG80619.1|3092989_3093574_-|hypothetical-protein	gnl|CDD|377450	pfam05076, SUFU, Suppressor of fused protein (SUFU). SUFU, encoding the human orthologue of Drosophila suppressor of fused, appears to have a conserved role in the repression of Hedgehog signaling. SUFU exerts its repressor role by physically interacting with GLI proteins in both the cytoplasm and the nucleus. SUFU has been found to be a tumor-suppressor gene that predisposes individuals to medulloblastoma by modulating the SHH signaling pathway. Genomic contextual analysis of bacterial SUFU versions revealed that they are immunity proteins against diverse nuclease toxins in polymorphic toxin systems.	2.81732e-27
CP032698.1|AYG80603.1|3077216_3078467_-|hypothetical-protein	gnl|CDD|371483	pfam11350, DUF3152, Protein of unknown function (DUF3152). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	1.32653e-64
CP032698.1|AYG80618.1|3090945_3092187_+|Multidrug-efflux-protein-YfmO	gnl|CDD|341027	cd17474, MFS_YfmO_like, Bacillus subtilis multidrug efflux protein YfmO and similar transporters of the Major Facilitator Superfamily. This family is composed of Bacillus subtilis multidrug efflux protein YfmO, bacillibactin exporter YmfD/YmfE, uncharacterized MFS-type transporter YvmA, and similar proteins. YfmO acts to efflux copper or a copper complex, and could contribute to copper resistance. YmfD/YmfE is involved in secretion of bacillibactin. The YfmO-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.01332e-94
CP032698.1|AYG80606.1|3079973_3080615_+|putative-HTH-type-transcriptional-regulator-TtgW	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	4.12962e-15
CP032698.1|AYG80621.1|3095224_3096127_-|hypothetical-protein	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	8.09294e-09
CP032698.1|AYG80616.1|3089013_3089889_-|5'-3'-exoribonuclease	gnl|CDD|223686	COG0613, COG0613, Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only].	3.75595e-47
CP032698.1|AYG80620.1|3094059_3095184_+|Cobalt/magnesium-transport-protein-CorA	gnl|CDD|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	8.93001e-171
CP032698.1|AYG80612.1|3086761_3087688_-|hypothetical-protein	gnl|CDD|224349	COG1432, COG1432, Uncharacterized conserved protein [Function unknown].	7.39628e-06
CP032698.1|AYG80610.1|3082963_3085345_+|ATP-dependent-RNA-helicase-CshA	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	3.43293e-138
CP032698.1|AYG80614.1|3088234_3088840_-|hypothetical-protein	gnl|CDD|225006	COG2095, MarC, Multiple antibiotic transporter [Intracellular trafficking and secretion].	1.25699e-39
CP032698.1|AYG80611.1|3085444_3086317_+|Epoxide-hydrolase-B	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.92353e-19
CP032698.1|AYG80602.1|3075130_3076861_-|Periplasmic-oligopeptide-binding-protein	gnl|CDD|173871	cd08506, PBP2_clavulanate_OppA2, The substrate-binding domain of an oligopeptide binding protein (OppA2) from the biosynthesis pathway of the beta-lactamase inhibitor clavulanic acid contains the type 2 periplasmic binding fold. Clavulanic acid (CA), a clinically important beta-lactamase inhibitor, is one of a family of clavams produced as secondary metabolites by fermentation of Streptomyces clavuligeru. The biosynthesis of CA proceeds via multiple steps from the precursors, glyceraldehyde-3-phosphate and arginine. CA possesses a characteristic (3R,5R) stereochemistry essential for reaction with penicillin-binding proteins and beta-lactamases. Two genes (oppA1 and oppA2) in the clavulanic acid gene cluster encode oligopeptide-binding proteins that are required for CA biosynthesis. OppA1/2 is involved in the binding and transport of peptides across the cell membrane of Streptomyces clavuligerus. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	4.13995e-180
CP032698.1|AYG80604.1|3078475_3079471_-|Lipase-1	gnl|CDD|184875	PRK14875, PRK14875, acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional.	2.95136e-27

Protein sequences

>CP032698.1|AYG80611.1|3085444_3086317_+|Epoxide-hydrolase-B
MSKPRSLDLPARTRAYRLRTARQEFAVLDSRPEGRALGTVLLVPGYTGSKEDFLALLDPLADAGYRAVAVDGRGQFESPGPRRTSAYTPRQLGGDVLAQVAALGDGPVHLVGHSFGGFVARSAARLDPSAFRSLTLLSSGPGRVGPDQRTKIRLLRAALPVLPPSWVWAATVWLDGRDPAYVSDPPEIVEFLQRRWFSTQPAQLIATGRQLRVEPDRTEGLARLPLPLHVAYGEGEMVWTVGELAHMARSVGARHTVIAGAEHSPNVSHPAELASALSAFWSTTPTPPHP
>CP032698.1|AYG80610.1|3082963_3085345_+|ATP-dependent-RNA-helicase-CshA
MSPFPIQEMTLPVALSGSDIIGQAKTGTGKTLGFGLPILERVIVPADVEAGRATSDQLTNTPQALVVVPTRELCQQVTNDLLTAGKVRNVRVLAIYGGRAYEPQVEALKKGVDVIVGTPGRLLDLAGQKKVDLSHVKVLVLDEADEMLDLGFLPDVEKIIQLLPPKRQTMLFSATMPGAVIGLARRYMSQPTHIRATSPDGEGTTVANTEQFVYRAHSMDKPEMVARILQAEGRGLAMIFCRTKRTAADIAEQLAKRGFASGAVHGDLGQGAREQALRAFRNGKVDVLVCTDVAARGIDVDGVTHVINYQSPEEEKTYLHRIGRTGRAGKKGIAITLVDWDDIPRWQLINKALDLKFPDPPETYSTSPHLFEELRIPKGTKGVLPRGERTRAGLAAEEVEDLGETGGRGRKSAAAAPVVTEERPPRTRTPRQRRRTRGGSQDGVETPAAAPAPAPVAEAPVTEATEQVTEARTPRRRRRTRVGAPSNAPQAAAAPVIEAASAAPVAEPVTKAEPRRRTASAAPAVTPEPVKAEPRRRPAPAATVAVPEPAKAEPRRRRVRKVVDTSSEVGFMTPESAALELARAAKAKTTAAMTEVASAPAAAVTAAPVTAAPEKPRRTRAKKAAEAVVETVEAPAAVETEAPAKPRRTRAKKVAEAAPETVVEAAAEAEAPAKPRRTRAKKAAEAVVETVEAPATVETEAPAKPRRTRAKKAAEAAPEATEAPAAPRRTRAKKVAEAAPETVVEAAAEAEAPAKPRRTRAKKAAVAPEAVEAEAPAKPRRTRAKKAAVAPEA
>CP032698.1|AYG80609.1|3081753_3082605_-|hypothetical-protein
MCVGRIRGTGDSGVRKQALTAHPGRAIVRLMETSDNATAAEGTTPEPERTGIAAQDWATASAVPQYRAAVVDLLGALAYGELAAFERLADDAKLAPTLADKAELAKMASAEFHHFERLRDRLAQVDAEPTAAMEPFAKALDDFHQQTAPSDWLEGLVKAYVGDSIASDFYREVANHLDTDTRSLVLAVLDDTGHGNFAVEKVRAAIEADPRVGGRLALWARRLMGEALSQAQRVVAERDALSTMLVGGVDGVAAGFDLAAVGEMFTRITKAHTKRMAALGLAA
>CP032698.1|AYG80608.1|3081197_3081461_+|hypothetical-protein
MLLEAIGSVLLGFALAWAAAARLAHRLPDRRTVLGVGPLAGLFGAFLTHSAIGPGHGVTTVLGAAFVASVTLSLLLRPTRRLRRWAA
>CP032698.1|AYG80607.1|3080756_3080984_+|hypothetical-protein
MEVKIGVQHAPREIVLESGQSAEEVESAVADALAGKAQLLSLTDDKGRKVLVPADKIAYVEIGEPAVRRVGFGAL
>CP032698.1|AYG80606.1|3079973_3080615_+|putative-HTH-type-transcriptional-regulator-TtgW
MTAIEQTEAARPRGTRLPRRARRNQLLGAAQEVFVAQGYHAAAMDDIAERAGVSKPVLYQHFPGKLDLYLALLDQHCESLLHAVRTALASTSDNKLRVAATMDAYFAYVEDEGGAFRLVFESDLTNEPAVRERVDRVSLQCAEAISDVIAEDTGLSKDESMLLAVGLGGVSQVVARYWLSSESTIPRDKAVQLLTSLAWRGIAGFPLHATEGH
>CP032698.1|AYG80605.1|3079607_3079829_+|hypothetical-protein
MSVDPSDPETFQEAEEGTPRVPDETNEADAAEQHTDVRQDRDEPLSHVDPGTANEADAVEQTRVVSLDEDDYR
>CP032698.1|AYG80604.1|3078475_3079471_-|Lipase-1
MSSTELPETPAAAALAPRVSPVGAAEGEELRRVSLPGLTLAVRSRPGTRAGLDPALYVHGFGGSSRNWSALMALLADRVDGEALDLPGFGDSPPPDDGAYTVTAQARAVIRLLDSTGRGPVHLIANSLGGAVCTRVAAVRPDLVRTLTLVSPALPEIRVQRGAWPTALIAVPGVASLFAKMTRDWTAEDRTRSALALSYGDPARITPEGLESAVRELERRLQLPYFWDAMVRSARGIVDAYTLGGQHGLWRQAERVLAPTLLVYGTRDRLVSYRMARRAAAAYRDSRLLTLPDAGHVAMMEYPDTVARAVRELIDDTSGGRHRGDDRENRS
>CP032698.1|AYG80603.1|3077216_3078467_-|hypothetical-protein
MGRHSRPKATGAEGPIPQARAPRAPEAGQAATPGGGRRRRPAQGDGPETHHGAGTPAFGTPQVRGGHPQHREDGPGAGYVGRHGAGYGTPRPAQQSPNGTAPRIPGPRRSSIEAFDGPGPARTDTPRTVAVPAPARPEPAAPAPETKPKASKGRTFTGIAAAAVTTVLAVVVAGQVTSDGDKHDVAGRTAGDKHRDDDGSASRGSGRSTPQAAPAVLTYDQKMAQQFPLDAGLTASGTFETVPGAAGAPGKGTKYRYRVDVEKGLALDGGLFADAVQKTLNDDRSWAHAGKMTFERISSGKPDFVITLASPGTTGAWCAKSGLDTTEDNVSCDSAATDRVMINAYRWAQGSVTFGPKAMLAYRQMLINHEVGHRLGHDHESCRTPGAPAPVMQQQTKSLDLKGIKCLPNPWVYPGS
>CP032698.1|AYG80602.1|3075130_3076861_-|Periplasmic-oligopeptide-binding-protein
MRHTSISSGNVARAAAIAVVLAMGAVACGPEGGDAENAGAGASGTPHEGGTLSVLNNEAQTTFDPARLYTSGGGNVPSLVFRTLTTRKRANGAEGTKVVPDLATDTGRPNADATVWTYTLKDGLKYEDGSPITTADIKYGIERSFAAELSGGAPYLRDWLVGGAQYQGPYKDGGKQLASIETPDAKTIVFHLNKPEGEFPFLATQTQFAPVPKARDNGTKYAEHPVSSGPYKVVKNENDGEHLVLERNPNWSEATDPERKAYPDSIDVRSGLDQAVINQRLSASQGPDAAAVTTDTNLGPAELAKVGSDKRLAARVGTGHFGYTNYIAFNPNVKPFDDPKVRQAIAYAVDRTSVVNAVGGSSLAEPATTFLPNQKAFGYTPYDLFPAGESGNAAKAKELLKEAGHADGLTVTLTHSNAKGGPKGPEVATALQDALKKAGITVKLQGLEGNDYNDTVASAKKEPGFFLRGWGADWPSGGPFLAPIFDGRQIVRDGANFNTGFLNDASVNSEIDEINKLTDLTAAAPRWGALDKRIGEQAVVVPLFHPVYKRLVGKDVKNVVISDWTGVLDISQVAVK
>CP032698.1|AYG80612.1|3086761_3087688_-|hypothetical-protein
MDDSQEPQPARAPHDPVAQLDRKLDATNELLQRMLAEVAKTPSTHAIFVDAGYVYAAAGLLVTGTEDRRSFDLDAEGLIDAFIDKARTIFADSRLLRVYWYDGARRRIHTPEQQSIAELPDVKVRLGNLNANNQQKGVDSLIRSDLESLARHRAISDAALIGGDEDLVSAVEAAQGYGARVHLWGIEAAEGRNQAEPLLWEVDSQRTFDLDFCKPYVTRRPVTLYEDGPAPSREDVRFVGARIAATWLSERGRAALADLLPGHPYLPGPVDQDLLIEAERLLQRSLRGHADLRRALRDGFWQHLQSQY
>CP032698.1|AYG80613.1|3087965_3088118_+|hypothetical-protein
MRFEIMRLDDVDGIAVDSTVVDAASVNRIVQQAAAMGQRIYIRPTESAAS
>CP032698.1|AYG80614.1|3088234_3088840_-|hypothetical-protein
MFDAAVFGSLFLTLFVIMDPPGITPIFLALTAGRAAKVQRRMAWQAAAVALGVITLFGLVGHQILTYLHIDVPALMIAGGLLLLLIALDLLTGKTDEPQQTKDVNVALVPLGMPLLAGPGAIVQVILAVQNHDSVAGQVSVWAAIIAIHVVLYVTMRYSLLIIRVIKDGGVVLVTRLAGMMLSALAVQQIINGITQVIHAY
>CP032698.1|AYG80615.1|3088867_3089086_+|hypothetical-protein
MRGGRDAVARAGRARPPGRARKVVRAGCEERGYGDGVPGVRRGGLSLPGYGQVVPPAPGTGKAPVARRVISP
>CP032698.1|AYG80616.1|3089013_3089889_-|5'-3'-exoribonuclease
MRIDLHTHSTASDGTDTPAELVRNAAAAGLDVIALTDHDTTRGYAEAIAALPGLDRDLTLVTGAELSCRLDGVGLHMLAYLFDPEEPELARERELVRDDRVPRAQGMVTKLQELGVPVTWEQVARIAGDGSIGRPHVAEALVELGVVDSVSDAFVPEWLADGGRAYVGKHELDPFEAIRLVKAAGGVTVFAHPLAVKRGQVVPESAIAELAAAGLDGIEVDHTDHDAPTRDRLRALARDLGLLATGSSDYHGSRKTVRLGEWTTDPEIYGEITRRATGAFPVPGAGGTTCP
>CP032698.1|AYG80617.1|3090107_3090746_-|hypothetical-protein
MRGEPSCPKCGGRVRAPGLFADTWQCDAHGPVYPLQPVVPPSVEALEVVVRRAQVPVWMPWPLPVGWLFTGVAYAGDDRSGGRATAVACSGPGPLGGLGELILVAEELGVGLGARYAGIEGPDPGPFMSVDKPPHTKVLAAGRPTPLWHVTRTPDDRAVFAGEARGLWLWAIVWPEQSGLLMYDELVLTDLRDAGAEVELLPCGALTPRILS
>CP032698.1|AYG80618.1|3090945_3092187_+|Multidrug-efflux-protein-YfmO
MRQGTDPLDDGAGTGGLLRQPKAVWATAGASVVAFMGIGLVDPILPSIAKGLDATPSQVSLLFTSYFLITAVAMLVTGFVSSRIGGKKTLLAGLALVVVFAALAGTSNSVGELVGFRAGWGLGNALFVSTALAVIVGAAAGGSAAAILLYESALGLGMACGPLLGAVLGDMKWRYPFFGTAALMAIGFLAITVFLKEQPKPARKTSLLDPLKALGHGGLASAAASAFFYNYAFFTVLAFTPFVLNMSPYKSGGVFFAWGVLLAVFSVLVAPRLQERFGSLKVLGGSLVLLAADLIVLGYGNHTTAVAATVASGAFIGLNNTVYTELALGVSDAPRPVASAGYNFVRWFAAAAAPYFAPKIEEWSDLHIPFVVAAGAAVVGAGIVWVRRGVLTREVAGLRPGHAVEDGVSVFAN
>CP032698.1|AYG80619.1|3092989_3093574_-|hypothetical-protein
MVDVLALVEARLRTALGEPDARAAVTFLGTDRIEVLRFTDGDIVRYATLGMSAQPMADPTAALADPVKGPRAELVLSVRAGLADTDKVLRPLAVLAASPQVEGVVVAPGASLDLGEPLWPGAAFGSVLVAEPGGLIEDLELDAPMDPVRFLPLLPMTANEAAWKRVRGAAELEGRWLARGTDLRDPLRPSVPLD
>CP032698.1|AYG80620.1|3094059_3095184_+|Cobalt/magnesium-transport-protein-CorA
MSMIRDLRAVVRPALRKTSTPYNGYDTTRDPSASSAVVDCAVYRDGRRVQSVEETSCLTPREAMRRVREGGGFVWIGLHEPTEAEFAGIAAEFGLHPLAVEDAVHAHQRPKLERYDDTLFTVFKTIHYVEHAELTATSEVVETGEVMCFTGPDFVITVRHGGQGSLRALRKRLQDDPELLSKGPSAVLHAIADQVVDGYLAVVDAVQDDIDEVEIEVFSAPAKGSPRGVDAGRIYQLKREVLEFKRAVSPLLRPMQLLSERPMRLVDPDIQKYFRDVADHLARVQEQVVGFDELLNSILQANLAQASVAQNEDMRKITSWAAIIAVPTMVCGVYGMNFDHMPELHWKYGYPISMGLVAVACFAIHRTLKRNGWL
>CP032698.1|AYG80621.1|3095224_3096127_-|hypothetical-protein
MTTATTPAQNVAAVPRVDIVLLGVALASVSLSAPLIAATAAPALAIAFWRNALAVGVLTPVAWFKHRARLRALTRREVGLTVGAGALLALHFGLWLPSLSMTSVASSTALCTTTPIWTTLALRLRGHRPPALVWSGTLAACVGVVLLTGVDLTLSPRALAGDALALGGGIAAAGYVLLGAEVRKSVATVPYTYLCYGTAAAGLLAATLVSGADLTSYDAGTWAKLGLLTLAAQLLGHSLLNRVVASLGPSVTSTAILLETPGAALIAALWLGQEPPVLAYPALAVILAGLALVVRAGRGA

Crispr_ID: CP032698_17

• CRISPR_ID: CP032698_17
• CRISPR_location: 3328014-3328109
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_17

Consensus_repeat	Method
GGGGTCTGGGGCGCAGCCCCAGGG	CRISPRCasFinder

spacers of CP032698_17

>17.1|3328038|48|CP032698|CRISPRCasFinder
CTCAGCCCGTTCAACCCGCCGCACGGGCGGGTGGGTGGGCAAACCCGC

CRISPR arrays and Neighbor proteins around CP032698_17

CRISPR arrays

The CRISPR arrays of CP032698_17

>merge|CP032698|17|3328014-3328109|CRISPRCasFinder
GGGGTCTGGGGCGCAGCCCCAGGGCTCAGCCCGTTCAACCCGCCGCACGGGCGGGTGGGTGGGCAAACCCGCGGGGTCTGGGGCGGAGCCCCAGGG

>CP032698|17|13|3328014-3328109|CRISPRCasFinder
GGGGTCTGGGGCGCAGCCCCAGGG	CTCAGCCCGTTCAACCCGCCGCACGGGCGGGTGGGTGGGCAAACCCGC
GGGGTCTGGGGCGGAGCCCCAGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80813.1|3318670_3320272_+|N-acyl-D-glutamate-deacylase	unknown	unknown	gnl|CDD|238622
CP032698.1|AYG80826.1|3335648_3336146_+|Transcription-elongation-factor-GreA	unknown	unknown	gnl|CDD|234693
CP032698.1|AYG80821.1|3328166_3330191_-|hypothetical-protein	unknown	unknown	gnl|CDD|224250
CP032698.1|AYG80814.1|3320201_3320540_-|hypothetical-protein	unknown	unknown	gnl|CDD|379707
CP032698.1|AYG80815.1|3320671_3322108_-|hypothetical-protein	unknown	unknown	gnl|CDD|365907
CP032698.1|AYG80824.1|3334013_3334895_-|Mycothiol-S-conjugate-amidase	unknown	unknown	gnl|CDD|132487
CP032698.1|AYG80816.1|3322216_3322861_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80822.1|3330306_3333552_+|Regulatory-protein-AfsR	unknown	unknown	gnl|CDD|276809
CP032698.1|AYG80820.1|3327052_3327733_+|hypothetical-protein	unknown	unknown	gnl|CDD|273425
CP032698.1|AYG80825.1|3335023_3335425_+|hypothetical-protein	unknown	unknown	gnl|CDD|379491
CP032698.1|AYG80811.1|3315765_3316884_-|2-dehydro-3-deoxygluconokinase	unknown	unknown	gnl|CDD|238571
CP032698.1|AYG80817.1|3322928_3324140_+|putative-aspartate-aminotransferase	unknown	unknown	gnl|CDD|181738
CP032698.1|AYG80823.1|3333772_3333994_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80819.1|3324921_3326745_-|Phosphoenolpyruvate-carboxykinase-[GTP]	unknown	unknown	gnl|CDD|235256
CP032698.1|AYG80818.1|3324250_3324637_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80828.1|3337054_3338068_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	unknown	unknown	gnl|CDD|130256
CP032698.1|AYG80812.1|3317016_3318306_+|D-threonine-aldolase	unknown	unknown	gnl|CDD|143492
CP032698.1|AYG80830.1|3339630_3340134_+|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
CP032698.1|AYG80829.1|3338246_3339476_-|L-threonine-ammonia-lyase	unknown	unknown	gnl|CDD|236182
CP032698.1|AYG80827.1|3336212_3337058_-|Daunorubicin/doxorubicin-resistance-ABC-transporter-permease-protein-DrrB	unknown	unknown	gnl|CDD|366444

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80813.1|3318670_3320272_+|N-acyl-D-glutamate-deacylase	gnl|CDD|238622	cd01297, D-aminoacylase, D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics.	8.8919e-103
CP032698.1|AYG80826.1|3335648_3336146_+|Transcription-elongation-factor-GreA	gnl|CDD|234693	PRK00226, greA, transcription elongation factor GreA; Reviewed.	8.13843e-57
CP032698.1|AYG80821.1|3328166_3330191_-|hypothetical-protein	gnl|CDD|224250	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones].	0
CP032698.1|AYG80814.1|3320201_3320540_-|hypothetical-protein	gnl|CDD|379707	pfam14863, Alkyl_sulf_dimr, Alkyl sulfatase dimerization. This domain is found in alkyl sulfatases such as the Pseudomonas aeruginosa SDS hydrolase, where it acts as a dimerization domain.	1.70548e-06
CP032698.1|AYG80815.1|3320671_3322108_-|hypothetical-protein	gnl|CDD|365907	pfam00150, Cellulase, Cellulase (glycosyl hydrolase family 5).	2.66175e-28
CP032698.1|AYG80824.1|3334013_3334895_-|Mycothiol-S-conjugate-amidase	gnl|CDD|132487	TIGR03446, mycothiol_Mca, mycothiol conjugate amidase Mca. Mycobacterium tuberculosis, Corynebacterium glutamicum, and related species use the thiol mycothiol in place of glutathione. This enzyme, homologous to the (dispensible) MshB enzyme of mycothiol biosynthesis, is described as an amidase that acts on conjugates to mycothiol. It is a detoxification enzyme. [Cellular processes, Detoxification].	4.34839e-178
CP032698.1|AYG80822.1|3330306_3333552_+|Regulatory-protein-AfsR	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.42984e-07
CP032698.1|AYG80820.1|3327052_3327733_+|hypothetical-protein	gnl|CDD|273425	TIGR01065, Hypothetical_UPF0073_protein_yqfA., channel protein, hemolysin III family. This family includes proteins from pathogenic and non-pathogenic bacteria, Homo sapiens and Drosophila. In Bacillus cereus, a pathogen, it has been show to function as a channel-forming cytolysin. The human protein is expressed preferentially in mature macrophages, consistent with a role cytolytic role.	2.92867e-45
CP032698.1|AYG80825.1|3335023_3335425_+|hypothetical-protein	gnl|CDD|379491	pfam14155, DUF4307, Domain of unknown function (DUF4307). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 132 and 153 amino acids in length. There is a single completely conserved residue C that may be functionally important.	1.08566e-28
CP032698.1|AYG80811.1|3315765_3316884_-|2-dehydro-3-deoxygluconokinase	gnl|CDD|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	8.63223e-85
CP032698.1|AYG80817.1|3322928_3324140_+|putative-aspartate-aminotransferase	gnl|CDD|181738	PRK09265, PRK09265, aminotransferase AlaT; Validated.	0
CP032698.1|AYG80819.1|3324921_3326745_-|Phosphoenolpyruvate-carboxykinase-[GTP]	gnl|CDD|235256	PRK04210, PRK04210, phosphoenolpyruvate carboxykinase (GTP).	0
CP032698.1|AYG80828.1|3337054_3338068_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	7.61442e-116
CP032698.1|AYG80812.1|3317016_3318306_+|D-threonine-aldolase	gnl|CDD|143492	cd06818, PLPDE_III_cryptic_DSD, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase. This subfamily is composed of Burkholderia cepacia cryptic D-serine dehydratase (cryptic DSD), which is also called D-serine deaminase, and similar bacterial proteins. Members of this subfamily are fold type III PLP-dependent enzymes with similarity to bacterial alanine racemase (AR), which contains an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. AR exists as dimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. Based on similarity, it is possible cryptic DSDs may also form dimers. Cryptic DSDs are distinct from the ubiquitous bacterial DSDs coded by the dsdA gene, mammalian L-serine dehydratases (LSD) and mammalian serine racemase (SerRac), which are fold type II PLP-dependent enzymes. At present, the enzymatic and biochemical properties of cryptic DSDs are still poorly understood. Typically, DSDs catalyze the dehydration of D-serine to aminoacrylate, which is rapidly hydrolyzed to pyruvate and ammonia.	4.20403e-153
CP032698.1|AYG80830.1|3339630_3340134_+|putative-HTH-type-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.86751e-20
CP032698.1|AYG80829.1|3338246_3339476_-|L-threonine-ammonia-lyase	gnl|CDD|236182	PRK08198, PRK08198, threonine dehydratase; Provisional.	0
CP032698.1|AYG80827.1|3336212_3337058_-|Daunorubicin/doxorubicin-resistance-ABC-transporter-permease-protein-DrrB	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	2.18132e-16

Protein sequences

>CP032698.1|AYG80820.1|3327052_3327733_+|hypothetical-protein
MTDQVTARAIDPVTQMVKPKMRGWLHAGMFPAVLISGLALIAFADSPTARISCGIFVLTACLLFGTSGIYHRGTWGPRGEAILRRLDHANIFLIIAGTYTPLTLLLLPGSTGQVLLWAIWGAALAGIAFRVFWINAPRWLYTPCYLAMGWAAVFFLPDFARTGGIAVLVLIIVGGLLYSAGGVIYGLKRPNPSPAFFGFHEVFHSLTLAAYVAHYVGISLAVHQHG
>CP032698.1|AYG80819.1|3324921_3326745_-|Phosphoenolpyruvate-carboxykinase-[GTP]
MARDIAAPLSVPTKHQELISWVNEIAELTQPDSVVWCDGSEAEYERLCGELVAKGTFKKLDEAKRPNSYYAASDPRDVARVEDRTFICSEKEEDAGPTNHWKAPAEMKDLFAGEKGIFRGSMRGRTMYVVPFCMGPVGSPLSAIGVEITDSAYVAVSMRTMTRMGQRVLDELGTDGFFVKAVHTLGAPLAEGEADVPWPCNTTKYISHFPESREIWSYGSGYGGNALLGKKCYALRIASVMARDEGWLAEHMLVLKLTPPNGEAKYVTAAFPSACGKTNLAMLEPTIPGWKVETIGDDIAWMRFGEDGQLYAINPEAGFFGVAPGTGEHTNANAMKTLWGNSVFTNVALTDDGDVWWEGMTETAPAHLTDWKGEEWTPASDTPAAHPNARFTVPAGQCPTIAPEWEDPKGVPISAILFGGRRASAVPLVTESFDWNHGVFLGANVASEKTAAAEGKVGELRRDPFAMLPFCGYNMGDYMAHWVKVGAQADAAKLPKIYYVNWFRKNDAGKFVWPGFGENSRVLKWIVERLEGKAEGVETPIGILPTKESLDTDGLDLPEADLDFLLKVDTEVWREEAALVPEHLNTFGDHAPKELWDEYRALVSRLG
>CP032698.1|AYG80818.1|3324250_3324637_+|hypothetical-protein
MYEPIRTKSVHSTVAADDTRIPHRSREEELDIQLAGHLSALLAVTDELGLTEAGDAIARQIARLRGGLPPVRHAGLSGADPKALHTRAHALAGRALLVAASRADTAAAILAAERMDAHAAADALPTAA
>CP032698.1|AYG80817.1|3322928_3324140_+|putative-aspartate-aminotransferase
MQVIQSTKLANVCYEIRGPVLEEAMRLEAAGHRILKLNTGNPAAFGFECPPEILEDILRNLSGAHGYGDAKGLLSARRAVMQHYQTKGIELDVEDVYLGNGVSELIQMSMQALLDDGDEVLVPAPDYPLWTASVSLAGGTAVHYRCDEQSDWMPDLADIERKVTDRTKAIVIINPNNPTGAVYDDEMLRGLTEIARRHNLVVCSDEIYDRILYDGATHTPTAVIAPDLMVLTFNGLSKNYRVAGYRSGWLAVCGPKAHASSYIEGLTILANMRLCANMPSQHAVATALGGRQSIEQLVLPGGRLLEQRDTAYELLTRIPGVTCVKPKGALYLFPRLDPNVYKVKDDRQMVLDLLRAEKIMVVHGTGFNWPEPDHFRIVTLPSTKDLADAVTRIGTFLDGYSQM
>CP032698.1|AYG80816.1|3322216_3322861_+|hypothetical-protein
MRLPRIEPAVVAVTGLCLLLALLLGLTPVLTAFTAHGGAVLVPSALGVPLALPPLRAVPLGDTGWTLLLCEDFAVVVLTAVAGLRMRRHLRLRPAASRPRRLLAGWSALIAGAAAAGVWRGLVTARLVDAGPLGWLLYAAAGALFGAVWGAGLGWLTAVAALARPRGPGRTGVGKISPPPDHSPFQAGFQAGPRPAPRIPPGRPTPPHCDGSRP
>CP032698.1|AYG80815.1|3320671_3322108_-|hypothetical-protein
MGIRGIRWAAAGATAAVAAALLVAVGPAQAGPPRTATGHRWITDDQGRALVLTGLNTASSAKSPPDGLPWIKEADVQRESDALGSNFVRFLIQWRTVEPSPGTYDDGYLDRVAERVRWYGARGYRVMLDLHQDVYGPAVKGNGAPVWATEAEGLPVAEQDQWELKYIEPGTVRAFDNFWGTREASRDLRAHYAAAWAHIAARFAHETAVVGYDLMNEPFGGSVQGPAFEAGPLAALYRRTITAIRAVDHDSWIFVEPEAVSANWGLPSGLPHLADPRGDADAARIAYAPHLYPLPMDLGGGYTANTGRWVDRTLASWREQTEKTARRLGAPVLIGEYGLDVTLPGALEYVAKVRALADAMGAGTAYWSNDPGSWAPWDQNLKATPLLPVLDRPAPRAVAGDPIAYAWDEPLRTLAVSWRPKEGVRGDTEVYLPARFFPHGGEVTGATAGAWDPRTRILHIAAGTPDTGEVSARIRPRE
>CP032698.1|AYG80814.1|3320201_3320540_-|hypothetical-protein
MTVTDRSRARLGWRGLLAAAQREYDAPAPRYDVVIELLDQVVGAAVPVAALRSAKALQALALTQLAYSAEYGPLRTVYLTAARGLTTGPLSAPRASAARNGPPARRSVCRPR
>CP032698.1|AYG80813.1|3318670_3320272_+|N-acyl-D-glutamate-deacylase
MDLVIRNAHVIDGTATPSYPADLGLTDGRISAIAHPGEPRLTANRTLDAHGLAVAPGFIDMHAHSDLALLRDPDHSAKAAQGVTLEVLGQDGLSYAPVDDRTLDEVRRAITGWNGDGADIDFDWRTVGEYLDRLDRGIAVNAAYLIPQGTVRMYAVGWDDRPATPQQMDHMRQLVAEGMEDGAVGMSSGLTYTPGMYAPDSELTELCRVVARYDGYYCPHHRSYGAGALEAYEEMVRLTGDAGCALHLAHATMNFGVNKGRAPELLALLDRALAGGADITLDTYPYTPGCTTLVALLPSWASEGGPEAILARLRDDDTAERIRHHLEVVGADGCHGVPVDWATIEISGVSDPGLAGCVGKTVAGAAAQRGEAPWVTARRLLIEDGLGSTILQHVGHEENVRAIMRHPAHTGGSDGILQGHKPHPRAYGTFPHYLGRYARELGVLSLEEAVAHLTSRPAARLRLPDRGLIREGYRADLVLFDPDTVAAGATFDAPRTLPVGIPHVLIDGKFVIEDGRRTGVLAGRSVRRTRGAR
>CP032698.1|AYG80812.1|3317016_3318306_+|D-threonine-aldolase
MAGTDRTANLAALGAERVDHRFKGLPPDAEGLTVAELAAERRNLFTGGFTTPVLALSAEAVEHNLALLETYAQRHGLAFAPHGKTSMAPQLFARQIERGAWGITLAVPHQVRVARAFGTERIFLANELVDAAALRWIAGELERDEAFEFICYVDSVRGVELMDQALRGSARRLDVVVELAAGEDARTGVRTEAECARVADAVAATGTLRLVGVAGYEGEVPRADPERVRAYLDRLVALAVAFDRAGRFAGLGVEEIVLSAGGSAWFDTVASAFADVPQLSLPVLKLLRSGAYVSHDDGHYRRLTPFNRVPSEGALRPAFQLWAQVVSRPSPEQAFVNAGKRDAAYDLDLPVAQVVRDAVTGVVREASGITVTGLSDQHGWLRTEGDVSLAVGDWVGFGLSHPCTVFDKWVLLPLTERDGTVADYIRTYF
>CP032698.1|AYG80811.1|3315765_3316884_-|2-dehydro-3-deoxygluconokinase
MTTGSPAAAHDADAPVDVVCLGESMVTFVPTRPGRLADVPAFARTIGGAESNVACALAAAGHRTRWVSRVGADGFGDHLIEAIGSYGVDVRAVRRDPERPTGVYFRTADDRAADGHEVLYYRAGSAASAMAPANVPRRDLWAGRILHLSGITAALSEDCLALMSDLMARPSPDHRPSPSRSAAPLLGGPGRPLVSFDVNHRPGLWRDAVGPRVLLELARGADLVFVGEDEAEAAWGLRGADAIRAALPEPEVLVVKRGAAGATVFAREDGAAGAMGAGCHAPSPRVDVVAPVGAGDAFAAGFLSATLRGLAVRDRIRHGHLMAAAVLTVPGDLTQPPARAHADRLVALDDTAWGRLRLGPGWTGDDQEVRTR
>CP032698.1|AYG80821.1|3328166_3330191_-|hypothetical-protein
MPNRLAHETSPYLLQHADNPVDWWPWSPEAFEEARERGVPVLLSVGYSSCHWCHVLAHESFEDEVTAAFMNEHFVNIKVDREERPDVDAVYMEAVQAATGQGGWPMSVFMTPDGEPFYFGTYFPPEPRHGMPSFRQVLEGVRGAWADRREEVTEVAEKITRDLAARELDHGAGGLPGEEELAQARLGITREYDPASGWLGGGDTKFPPGMVIEFLLRHHARTGSEAALEMAEGMCETMARSSLYDQLGGGFHRYVLRPRPGATLVPHFEKMLYDNALLCRVYAHLWRVTGSELARRVALETADFMVRELRTNEGGYASALDADSDDGTGRHVEGAFYVWTPAQLTEVLGEQDGLAAARHFGVTAEGTFEEGASVLQLPVEGGELSADAQSRLLAARELRERPGRDDKLVAAWNGLAIAAICEVGALFDRPDLVERATEAADVLVRVHMDAHARLARTSKDGQVGANRGVLEDYADVAEGFLALAGVTGEGVWLEFAGFLLDIVLDQFVGEGGVLYDTAHDAERLIRRPQDPTDNATPSGWTAAASALLSYAAHTGSSAHREAAESALGVVRALGPRAPRFIGWGLAAAEALLDGPREIAVVGAPTDPRTGALHRTALLSAAPGAVVAVGVPGGEEFPLLVDRPLVGGGPAAYVCRRFVCAAPVTTPESLADTLS
>CP032698.1|AYG80822.1|3330306_3333552_+|Regulatory-protein-AfsR
MRDSHRAEAERLLVRAVEEEVRRSGGRSDANTLLSRGRGALDALARSAAEEYDAYTRALDEAAAGQLSFGERFTRDGGPTALLATGVGALAALVADLGLGLGAGGAVGAGAAVLVAGAAATVAKVTASHVPAAHRRAGALGQPGGPEQLRLAWLTALEVRGIRPFLDQQRAVSPKAPQKKVPTQLRGTDKSAAARRRSVLEQSFGHLPDPRGPFAGRRVELARIGQWVQAARASTETRPVVVVLHGPPGSGRSTLAVRAAHALRDQFRGACLVDMRGGTLAGEGPLPTRDALLHLLNRLGAPREQLLFRGGVSPDRAESGPRGRSSSEQQVRRLAELYHQHLTGLPVTVVLDDTDDVEQVRTLVPQRSEGLVLVTSSRPLDLPADFPAWVHQLAVEPLDAAGAEELLRESAEEKETGPYDAESTELVRQLCGGLPLALRIAGSSLGPRSARALATDLGAYGPVAPTERALWLRYTDQSEPARRLLRRLALAGRASLGAAAAAALLAADEQEAERQLTALATAGLIDHVRGSRYRLHDVVRSFAQARLADEEEPAERAAAQERLIRNYAELADAVGRMVDGKMSTRAGQFGGHGFPSLDAALRWLDDESSFITAALRQAEGVDQEAVLSLLGALCDYCLLRGDLYRLGEISELTQAVDQGLLVRSVQWRTGIAARQLGELDTARTTLSSVVSLYREAHHDAGQALALCSLGITLHHQGNLAEAAARLREAIDLQSGEELSGDRAWSLHALAAVERDRANLSGALALLDAALALHRENESLHGEAWTHFQLGQLYLRTGEVARAEGELDTALELYGRTRDGRGEAWALTQRARARLVDGDAQTAVDGLNQALSRHREQEDARGEAWTLYYLGQALEERGDRDRAVRELERARTMFSRMRDVYGLACARHHSGRVTRDQRAAQTGNLRNSGFARQLLVDARADFHRIGVAHGEAWTCLELALIDAGNSRPGPALALCDEATALFASYDDRRGGDWSRFLRCTLLPYAGAGGVEVGTAVAQEEVAQLLRAGHGARDAKLEDCAQAYALMLERGISLEAGWQAWQLGMVPDRHAREVMGVPVEAGR
>CP032698.1|AYG80823.1|3333772_3333994_-|hypothetical-protein
MTHLAAPLAEEINNDKVTPGVLGFIVFAALALGVWMLMKSMNRHMGKVDFEESPDPSEATPATTGAKGAPNKV
>CP032698.1|AYG80824.1|3334013_3334895_-|Mycothiol-S-conjugate-amidase
MTEQLRLMAVHAHPDDESSKGAATMAKYVSEGVDVLVVTCTGGERGSILNPKLQGDKYIEEHIHEVRKREMDEAREILGVRQEWLGFVDSGLPEGDPLPPLPEGCFALEDVGLAAGPLVRSIRHFRPQVITTYDENGGYPHPDHIMTHKITMVAFEGAADTEKYPEAEFGPAFQPQKLYYNQGFNKPRTLALHEALLARGMESPYGEWLERWKEFERAERTLTTHVPCAEFFEIRDKALIAHATQIDPDGGWFRVPLDLQKEVWPTEEYELAKSLVDTSLPEDDLFAGVRDNA
>CP032698.1|AYG80825.1|3335023_3335425_+|hypothetical-protein
MAAVREQLPQGRYGRSADQRADRKLKIVGAALAAVLIAVVAWIGFDYVGGQSLSAQVIKFKVVSDTSVEVHLEVVKDKNAKGTCTLRAQQTSGDDVGRADFRFDEPVKQIDRVVTITTTSRATAADLVSCQSD
>CP032698.1|AYG80826.1|3335648_3336146_+|Transcription-elongation-factor-GreA
MTQTSDNVTWLTQEAYNQLKAELEYLSGPARTEIAVKIAAAREEGDLRENGGYHAAKEEQGKMELRVRQLTQLLEHAKVGEAPAADGVVAPGMLVTIAFDGDPDDTLEFLMASREYASTEIETYSPQSPLGSGVNGKKVGEDAEYELPNGKKASVKILAAVPFTG
>CP032698.1|AYG80827.1|3336212_3337058_-|Daunorubicin/doxorubicin-resistance-ABC-transporter-permease-protein-DrrB
MSTLTDAAPAPRAGGGIGGSVRDSLVVAKRNLIRMTRIPEMVIFGLIQPIMFVVLFSYVFGGSVNIGGTTDAGAYREFLMAGIFAQTVTFATAGAGAGIADDMHKGLIDRFRSLPMARGAVLTGRTLADLVQTTLTVVVLAIVALLVGWRIHNGLPKMLGAFALLLLLGYAFSWIGALIGLTVRTPEAATSGGLIWLFPVTFISNAFVNTSGMTPWLRHIAEWNPFSATVQACRKLFGNPGVVDSGAWPMQHPVWASLAWSLLIIVVFRTLAVRKYRSATA
>CP032698.1|AYG80828.1|3337054_3338068_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA
MPGAIYAEGLVKTFGNVTALDGVDLDVPEGTVLGLLGPNGAGKTTTVRVLTTLLQPDRGKAVVAGIDVLKHPNEVRRSIGLSGQFAAVDEYLTGRENLHMVGRLYQMNAKAAKVRAGELLDRFHLADAADRPAKTYSGGMRRRLDLAAALVVSPPVMFMDEPTTGLDPRNRQQLWEVIQELVAGGTTLLLTTQYLEEADRLAHDIAVVDHGKVIARGSSDQLKARTGGERVEVVVHQADQITPARDVLAGFGKGEVKIETHTRQLTVPVTGGAKLLAEVIRELDAQGVEIDDIGLRRPTLDDVFISLTGHAAETAKDEDTEAAEGRTPSKGRKEDTK
>CP032698.1|AYG80829.1|3338246_3339476_-|L-threonine-ammonia-lyase
MSFSTSGPLHHLILDDVRGAQKMLSGVARATAMEGSRHLSSLVGAPVHLKCENLQRTGSFKLRGAYVRIAGLRPEERAAGVVAASAGNHAQGVALASSLLGVRSTVFMPIGAPLPKVAATRSYGAEVILRGTVVDETLAAAEAYAAETGAVLIHPFDHQDIIAGQGTVGLEILEQCPEVRTIVVGIGGGGLAAGIAVAVKALRPDVRIVGVQAAAAAAYPPSLAVGHPVAIETAPTMADGIKVGRPGDIPFSLVSELVDEVRTVTEDELSSALLLCLERAKLVVEPAGASPVAALLSDPHGFRGPVVAVLSGGNVDPLLMQRILRHGMSAAGRYLSLRLRLTDRPGALASLLAELSVLDANVLDVSHVRTDPRLGLTEVEVEVHLETKGPEHCAEVASALREAGYTVLD
>CP032698.1|AYG80830.1|3339630_3340134_+|putative-HTH-type-transcriptional-regulator
MPPVQDMTPPLDPGLLDALQHQVAVFARRAEQTRLGGVGQVRNSMDRAAYLLLNRLDREGPMGVKALAAGMGIDSSTVTRQVAPLVDTGLVKRTSHPEDGRAVVLQLSPRGQSRLEEVRSSRRELMAQVTDGWTEDERESFCTLLTRFNSALSARQSAAHEPSAPTS

Crispr_ID: CP032698_18

• CRISPR_ID: CP032698_18
• CRISPR_location: 3355668-3355814
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_18

Consensus_repeat	Method
GGGTTAGGGGCGCGGGGAACTGCGCGA	CRISPRCasFinder
GGGTTAAGGGGCGCGGGGAACTGCGCGACCAGCCAC	PILER-CR

spacers of CP032698_18

>18.1|3355695|29|CP032698|CRISPRCasFinder
CCAGCCACGCACGGTGTGAGGCCGAAAGG
>18.2|3355751|29|CP032698|CRISPRCasFinder
GACGCGGGCACGGTCCGCACACGAAGGCG
>18.3|3355706|20|CP032698|PILER-CR
GCACGGTGTGAGGCCGAAAG
>18.4|3355762|28|CP032698|PILER-CR
GACGCGGGCACGGTCCGCACACGAAGGC

CRISPR arrays and Neighbor proteins around CP032698_18

CRISPR arrays

The CRISPR arrays of CP032698_18

>merge|CP032698|18|3355668-3355814|CRISPRCasFinder,PILER-CR
ACTTAAGGGGCGCGGGGAACTGCGCGACCAGCCACGCACGGTGTGAGGCCGAAAGGGGGTTAGGGGCGCGGGGAACTGCGCGAGACGCGGGCACGGTCCGCACACGAAGGCGGGTTCAGGGGCGCGGGGAACTGCGCGACCAGGCAC

>CP032698|18|14|3355668-3355806|CRISPRCasFinder
ACTTAAGGGGCGCGGGGAACTGCGCGA	CCAGCCACGCACGGTGTGAGGCCGAAAGG
GGGTTAGGGGCGCGGGGAACTGCGCGA	GACGCGGGCACGGTCCGCACACGAAGGCG
GGTTCAGGGGCGCGGGGAACTGCGCGA

>CP032698|18|5|3355670-3355814|PILER-CR
TTAAGGGGCGCGGGGAACTGCGCGACCAGCCACGCA	CGGTGTGAGGCCGAAAGGGG
GTTAGGGGCGCGGGGAACTGCGCGAGACGCGGGCAC	GGTCCGCACACGAAGGCGGGTTCAGGGG
CGCGGGGAACTGCGCGACCAGGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80854.1|3362809_3363421_+|Maf-like-protein	unknown	unknown	gnl|CDD|178901
CP032698.1|AYG80849.1|3357914_3359126_-|pH-sensitive-adenylate-cyclase	unknown	unknown	gnl|CDD|143636
CP032698.1|AYG80851.1|3360253_3361861_+|putative-propionyl-CoA-carboxylase-beta-chain-5	unknown	unknown	gnl|CDD|227136
CP032698.1|AYG80850.1|3359241_3360102_-|Bifunctional-ligase/repressor-BirA	unknown	unknown	gnl|CDD|223417
CP032698.1|AYG80844.1|3352986_3353370_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80852.1|3361891_3362098_+|hypothetical-protein	unknown	unknown	gnl|CDD|379386
CP032698.1|AYG80837.1|3347061_3347625_+|hypothetical-protein	unknown	unknown	gnl|CDD|340413
CP032698.1|AYG80838.1|3347855_3348062_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80846.1|3353803_3355351_-|Histidine-ammonia-lyase	unknown	unknown	gnl|CDD|236484
CP032698.1|AYG80856.1|3364297_3366052_+|Biotin-carboxylase	unknown	unknown	gnl|CDD|227111
CP032698.1|AYG80847.1|3355833_3356967_-|Phytochrome-like-protein-cph2	unknown	unknown	gnl|CDD|128563
CP032698.1|AYG80841.1|3349340_3350378_-|NADP-dependent-alcohol-dehydrogenase-C-1	unknown	unknown	gnl|CDD|176186
CP032698.1|AYG80842.1|3350537_3351392_+|hypothetical-protein	unknown	unknown	gnl|CDD|375319
CP032698.1|AYG80853.1|3362640_3362769_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80845.1|3353415_3353697_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80848.1|3357060_3357849_-|2,3-dehydroadipyl-CoA-hydratase	unknown	unknown	gnl|CDD|181069
CP032698.1|AYG80840.1|3348805_3349153_-|hypothetical-protein	unknown	unknown	gnl|CDD|377765
CP032698.1|AYG80843.1|3351405_3352674_-|L,D-transpeptidase-2	unknown	unknown	gnl|CDD|380079
CP032698.1|AYG80839.1|3348181_3348769_+|hypothetical-protein	unknown	unknown	gnl|CDD|379483
CP032698.1|AYG80855.1|3363428_3363896_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80854.1|3362809_3363421_+|Maf-like-protein	gnl|CDD|178901	PRK00148, PRK00148, Maf-like protein; Reviewed.	7.9704e-95
CP032698.1|AYG80849.1|3357914_3359126_-|pH-sensitive-adenylate-cyclase	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	1.01681e-30
CP032698.1|AYG80851.1|3360253_3361861_+|putative-propionyl-CoA-carboxylase-beta-chain-5	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
CP032698.1|AYG80850.1|3359241_3360102_-|Bifunctional-ligase/repressor-BirA	gnl|CDD|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	5.4584e-61
CP032698.1|AYG80852.1|3361891_3362098_+|hypothetical-protein	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	1.41842e-08
CP032698.1|AYG80846.1|3353803_3355351_-|Histidine-ammonia-lyase	gnl|CDD|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
CP032698.1|AYG80856.1|3364297_3366052_+|Biotin-carboxylase	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
CP032698.1|AYG80847.1|3355833_3356967_-|Phytochrome-like-protein-cph2	gnl|CDD|128563	smart00267, GGDEF, diguanylate cyclase. Diguanylate cyclase, present in a variety of bacteria.	2.06576e-39
CP032698.1|AYG80841.1|3349340_3350378_-|NADP-dependent-alcohol-dehydrogenase-C-1	gnl|CDD|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
CP032698.1|AYG80842.1|3350537_3351392_+|hypothetical-protein	gnl|CDD|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	6.49691e-69
CP032698.1|AYG80843.1|3351405_3352674_-|L,D-transpeptidase-2	gnl|CDD|380079	pfam17964, Big_10, Bacterial Ig domain. This entry represents a bacterial Ig-like domain found associated with transpeptidase domains.	4.08201e-69
CP032698.1|AYG80848.1|3357060_3357849_-|2,3-dehydroadipyl-CoA-hydratase	gnl|CDD|181069	PRK07657, PRK07657, enoyl-CoA hydratase; Provisional.	8.76521e-70
CP032698.1|AYG80840.1|3348805_3349153_-|hypothetical-protein	gnl|CDD|377765	pfam07045, DUF1330, Domain of unknown function (DUF1330). This family consists of several hypothetical bacterial proteins of around 90 residues in length. The function of this family is unknown.	3.1666e-25
CP032698.1|AYG80837.1|3347061_3347625_+|hypothetical-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	2.85712e-17
CP032698.1|AYG80839.1|3348181_3348769_+|hypothetical-protein	gnl|CDD|379483	pfam14124, DUF4291, Domain of unknown function (DUF4291). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 190 and 214 amino acids in length. There are two conserved sequence motifs: VYQAY and RMTW.	5.29003e-107

Protein sequences

>CP032698.1|AYG80846.1|3353803_3355351_-|Histidine-ammonia-lyase
MDMHTVVVGTSGTTPEDVIAVARHNAKVELSAEALAALARAREIVDALAAKPEPVYGVSTGFGALASRHISPELRAQLQRNIVRSHAAGMGPRVEREVVRALMFLRLKTVASGHTGVRPSVAQTMADVLNAGITPVVHEYGSLGCSGDLAPLSHCALTLMGEGDAEGPDGVVKPAGELLAAAGITPVELREKEGLALLNGTDGMLGMLCMAIADLKKLYTSADITAALTLEALLGTEKVLAPELHAIRPHPGQGASAANMLAVLKDSGLTGHFQEEEAPRVQDAYSVRCAPQVNGAGRDTIAYALTVAERELASAVDNPVVLPDGRVESNGNFHGAPVAYVLDFLAIVAADLASIAERRTDRLLDKNRSHGLPPFLADDAGVDSGLMIAQYTQAALVSEMKRLAVPASADSIPSSAMQEDHVSMGWSAARKLRTAVDNLTRVIAVELYAATRGIELRKGLTPAPASQAVIAAARAAGVQGPGPDRFLAPDLAAADAFVREGKLVAAVEPVTGPLA
>CP032698.1|AYG80845.1|3353415_3353697_+|hypothetical-protein
MSVARRPLLTATAAGTLLCALWFVPSANATDEQHPSAAPAHSAYRAAPTPAEGPLALADTGGPDTSPYLVGGTLFLGLGAGFVTYSVRRSRTC
>CP032698.1|AYG80844.1|3352986_3353370_-|hypothetical-protein
MLVKAAGRGKVAADSSPTLPRMSEEETSRYVRLRIDLVLEIADADRLAGAAVDRIAQDSAMRTEERTHAEAAVREDGAEALAYLVDPVDLVAALPGAELVQASWSSERVGYDPDDEEWDLDEDGDDD
>CP032698.1|AYG80843.1|3351405_3352674_-|L,D-transpeptidase-2
MEKRVKTESKRRKQGLAAACAVLGGVLVLSACNGDGDKGAKADSSSSSQAAADKAAEKDTSDAKITITPKNGADNVGINSDTKVTVADGKLTDVTLTSADGVKVAGKISADGLSWAPDKALKRSVKYQITATAADAKGRQAHENASFTTVSPKNSFIGSFTPEDGSTVGVGMPVSINFDKAITNKKGVQAKISVSSSSGQEVVGHWFGAQRLDFRPQEYWKENSTVTMKMDLDGVEASNGITGVQEKTVTFKIGRNQVSTVDANTHTMTVTQDGKVVKTIPISAGSPEHPTYNGQMVISEKYKETRMNGATVGFTDDDGKGEYDIKDVPHAMRLSASGTFIHGNYWGAKSIFGSANTSHGCVGLSDTKGAGDDGTMAAWFYNNSITGDVVVIKNSHDKTVQPDNGLNGWNMSWDQWKAGSAV
>CP032698.1|AYG80842.1|3350537_3351392_+|hypothetical-protein
MDQRAELSEFLRSRRARLKPEDVGLPDHGRRRRVPGLRREELAQLAGVSVAYYTRLEQGNAQNVSVEVLEAIGRALRLNDIEHDHLSHLAKGKTKKKRASACRPQQVRPALQQLIDAMEGVPAYIIGRRLDILGWNRMAAALFGDMGQLPSRERNMARHVFLDPAARSLYADWHSKAVDVVSVLRLCAGCYPDDPQLTALVGELSVKSEEFRALWAAHTVADKGHGVKRLHHPVVGELTLAYETLKLPDAHDLSLVTFHAEPGSTSEESLRLLGSWSAEQPVRT
>CP032698.1|AYG80841.1|3349340_3350378_-|NADP-dependent-alcohol-dehydrogenase-C-1
MTTVAAYAAPAAKAPLERTTIERRPVGPNDVAIEIKYAGICHSDIHQVNEGWGEAIFPMVPGHEIAGVITEVGSAVTAFQVGDRAGVGCFVDSCGKCEACRSGQNQFCSDGVSTYNAIGRDGKPAYGGYSTHIVVDADHTLRIPEGIALDVAAPLLCAGITLYSPLKRWQAGPGKKVAILGLGGLGHMGVKIAHALGAEVTVLSQSLRKKDDGLKLGADHYYATSDETTFERLAGSFDLIVSTVSAPLDLGAYLALLKTGGAFVNVGAPEEPNSLNMFGLIGGNKILAGSMIGGIAETQEMLDFCAEHSLGAEIELIRADQINEAYARVLDSDVRYRFVIDTATI
>CP032698.1|AYG80840.1|3348805_3349153_-|hypothetical-protein
MTAYAIANLRPAGGRPPHEDVFVYMERIQATLDPFGGRFLVHNAPLEVREGEWPHALVIIEFPAIEEARAWYDSPAYQALIPLRADHIPGDLILVDGVAPGYDPARTAAALRASA
>CP032698.1|AYG80839.1|3348181_3348769_+|hypothetical-protein
MEDRATPQRQIRALHTQSTVTVYQAYDPALGLPAARDGRFPAGWKRERMTWVKPSFLWMMYRSGWGTKEGQRTVLAVEIRRDGFDWALAHACLSHYERATHGEQAAWKRELRRAPARVQWDPERDLRLQALPYRSLQLGLAGEAVRRYADEWVVDIRDVTPLAHRVHALVGDGRLDAARALLPAERVYAGPPVNA
>CP032698.1|AYG80838.1|3347855_3348062_+|hypothetical-protein
MTDPRTTMGDPVHLALPHAPPKPARGCAVCAEMVARRRAAQRRGDLSAATDADVEIRHHPHRGRPRHR
>CP032698.1|AYG80837.1|3347061_3347625_+|hypothetical-protein
MDARNAERHKRVMSKRAASAPAVWGPRRSIYDPANGHFRSLTVYAESPDCARAARDMVGSYLRAWGLPRAVDDAQLVVSELVGNVVHHAVPDDCPTRPGGARKIDVLVKAWPGWLFIGVTDEDSSPPDLPAGELVSSELAGDFAEALLPDRGRGLLLVQRLADAVWWSPNGPSGKTIWCRFDLDGTA
>CP032698.1|AYG80847.1|3355833_3356967_-|Phytochrome-like-protein-cph2
MGGEDARLRAVVSLAQAMAAAHTPRESWRAAALGARCALGGNFAALSVWERELGRLRVLVNAGERAHGEEEFPEDETYPVHQFPEITEFLHERWAGGGEPNAWVETAAAPPEGDVGYCHERVTALRRRGRGCCVVAPIVLHGRAWGELYVARPVGVPVFDAADADFATVLASVAAAGIAQTERLEEVRRLAFTDPLTGLANRRAVDMRLDEAVERHRADDSVVSLVVCDLNGLKRVNDTLGHAVGDRLLERFGSVLSLCGAKLPGALSARLGGDEFCLLSVGPGADEVVAVGEELCLRAGELELGEGVACGVASTGDPIGPVVSARRLFRLADAAQYRAKAARSARPVVAGRDGAVLRLAENPPRPPHDRRRFRGRG
>CP032698.1|AYG80848.1|3357060_3357849_-|2,3-dehydroadipyl-CoA-hydratase
MAEQRFGEFVVVRREGYVAELVLDRPKAMNAVSTEMARSIAAACEALGADRDARVTVVSSTNERAFCVGADLKERNSFSDAELVRQRPTARAAYTGVLELPMPTVAAVHGFALGGGFELALACDVIVADATAVVGLPEVSVGVIPGGGGTQLLPRRVGAARAAELVFTARRVEAVEARELGLVDVLAEDARTEALALAGRMAANSPVGLRAAKRAMRLGHGLDLRAGLEVEDAAWRSVAFSGDRAEGVAAFNEKRKPAWPGE
>CP032698.1|AYG80849.1|3357914_3359126_-|pH-sensitive-adenylate-cyclase
MTVDETRSGADAGSGPGDTPGGSGTPAQAAPSAYPTPHHAVDHTAEPTDDPLAIRLEQLILGADRRYTPFQAARTAGVSMELASRFWRAMGFADIGQAKALTEADVLALRRLAGLVEAGLLSEPMAVQVARSTGQTTARLAEWQIDSFLEGLTEPPEPGMTRTEVTYPLVELLLPELEEFLVYVWRRQLAAATGRVVQAADDEEMVDRRLAVGFADLVGFTRLTRRLEEEELGELVEAFETTAADLVAAHGGRLIKTLGDEVLFAADDAGTAAEISLRLIETMAGDETMPALRVGIAFGTVTTRMGDVFGTTVNLASRLTSIAPKDAVLVDGAFAEELARTGDAPVSEAQAAQDALAAEKEGEDFPPPAKYRFALQPMWQRPVRGLGVVEPWLLRRREVPNLS
>CP032698.1|AYG80850.1|3359241_3360102_-|Bifunctional-ligase/repressor-BirA
MTPPDASDSRWSDLDRPPLNATALRRALLRPDALWTSLDVVTATGSTNSDLAAKADGLAEGAVLVAEEQTAGRGRLDRRWSAPARSGLFFSVLLKPGASVPVERWGWLPLLTGVAVAGGLARAAGVETALKWPNDLLVTVDGAERKAGGILAERAGADGVVVGIGLNVTLRADELPVPGAGSLALAGAVSTDRDTLLRAVLRSIEEWYASWRTASGDPAACGLHEAYAAACATLGRTVRAELPGGQSVEGEAVAVDGDGRLVLATGEGVQRPVAAGDIVHLRPAAS
>CP032698.1|AYG80851.1|3360253_3361861_+|putative-propionyl-CoA-carboxylase-beta-chain-5
MSEPENAQSDATVDLHTTAGKLADLQRRIDEATHAGSARAIEKQHAKGKLTARERVELLLDEGSFVELDEFARHRSTNFGIEKNRPYGDGVVTGYGTVDGRPVCVYSQDFTIFGGSLGEVYGEKIVKVMDFALKTGCPVIGINDGGGARIQEGVVALGLFAEIFRRNVHASGVVPQISLIVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNTTSGVAHHMAGDEKDAIEYVKSLLSYLPSNNLSEPPAFPEEADLETSDEDRELDALIPDSANQPYDMHTAIEHVLDEGEFLETQALFAPNIITGFGRVEGYPVGIVANQPMQFAGCLDINASEKAARFVRTCDAFNVPVLTFVDVPGFLPGVDQEYGGIIRRGAKLIYAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIAAAAPEDQEATRAELIADYEDTLLNPYIAAERGYVDAVIMPSETRAHIVRGLRQLRTKRESLPPKKHGNIPL
>CP032698.1|AYG80852.1|3361891_3362098_+|hypothetical-protein
MIKVVRGNPTPEELAAALAVVQARAAATASAASGAPEPPEGWSDPSRIARHALPRPGAHAWSRTYWPA
>CP032698.1|AYG80853.1|3362640_3362769_+|hypothetical-protein
MLWSDPDDKPPKELRDAQAMMRRAGLFLALAMVVAMIVVNIR
>CP032698.1|AYG80854.1|3362809_3363421_+|Maf-like-protein
MAHMTAPRRLVLASQSPARLGLLRQAGLAPEVIVSGVDEDALSAPTPSELALVLAEAKADAVAARPEASGALVIGCDSVLELDGLALGKPADAEDATARWKSMRGRSGVLRTGHCVIDTATGGRTSATASTVVHFGEPTDAELAAYVASGEPLYVAGAFTLDGRSAPFIDSIEGDPGNVIGLSLPLLRTLLAELGVPITELWV
>CP032698.1|AYG80855.1|3363428_3363896_-|hypothetical-protein
MLRRPIAIVAALILFAEACGIVLVNWVLGLVAHNQNMSLAGIDPHAISVGAWVAGGLFGLFLAVCGVLLLIVGIRDRAPGRIARITLIACAVVHAVLAAFTVGLVGWGAFAYLMVVLALLVLVLLAYARERPVAKAGPAPEDGTPPAPNGAPAAA
>CP032698.1|AYG80856.1|3364297_3366052_+|Biotin-carboxylase
MRKVLIANRGEIAVRVARACRDAGIASVAVYADPDRDALHVRTADEAFALGGDTPAASYLDIAKVLAAAADSGADAVHPGYGFLSENAEFAQAVLDAGLTWIGPPPQAIRDLGDKVAARHIAQRAGAPLVAGTPDPVSGADEVVAFAREHGLPIAIKAAFGGGGRGLKVARTLEEVPELYDSAVREAVAAFGRGECFVERYLDKPRHVETQCLADTHGNVVVVSTRDCSLQRRHQKLVEEAPAPFLTEAQNAELYAASKAILKEAGYVGAGTVEFLVGADGTISFLEVNTRLQVEHPVTEEVTGIDLVREMFRIADGEELGYGDPVMRGHSIEFRINGEDPGRGFLPAPGTVTLFSPPTGPGVRLDAGVESGSVIGPAWDSLLAKLIVTGATREQALQRAARALAEFTVEGMATAIPFHRAVVADPAFTADPFRIHTRWIETEFVNEIPAFTAPADAESDEEPGRETVVVEVGGKRLEVSLPSSLGMTLARTAAAGGAKPKRRAAKKTGSAASGDTLASPMQGTIVKVAVEEGQEVKEGDLVVVLEAMKMEQPLNAHRAGTVKGLAAEVGASVSSGAMICEIKD

Crispr_ID: CP032698_19

• CRISPR_ID: CP032698_19
• CRISPR_location: 3366110-3366205
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_19

Consensus_repeat	Method
CCCTGGGGCTCCGCCCCAGACCCC	CRISPRCasFinder

spacers of CP032698_19

>19.1|3366134|48|CP032698|CRISPRCasFinder
AACGTGTTCGCCCACCCACCCGCCCGTGACGGGGATCGAAGGGTCCGG

CRISPR arrays and Neighbor proteins around CP032698_19

CRISPR arrays

The CRISPR arrays of CP032698_19

>merge|CP032698|19|3366110-3366205|CRISPRCasFinder
CCCTGGGGCTCCGCCCCAGACCCCAACGTGTTCGCCCACCCACCCGCCCGTGACGGGGATCGAAGGGTCCGGCCCTGGGGCTCCGCCCCAGACCCC

>CP032698|19|15|3366110-3366205|CRISPRCasFinder
CCCTGGGGCTCCGCCCCAGACCCC	AACGTGTTCGCCCACCCACCCGCCCGTGACGGGGATCGAAGGGTCCGG
CCCTGGGGCTCCGCCCCAGACCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80859.1|3368302_3369889_-|NAD(P)H-dehydrogenase-(quinone)	unknown	unknown	gnl|CDD|236112
CP032698.1|AYG80866.1|3376286_3377399_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80856.1|3364297_3366052_+|Biotin-carboxylase	unknown	unknown	gnl|CDD|227111
CP032698.1|AYG80849.1|3357914_3359126_-|pH-sensitive-adenylate-cyclase	unknown	unknown	gnl|CDD|143636
CP032698.1|AYG80855.1|3363428_3363896_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80858.1|3367187_3368147_-|HTH-type-transcriptional-repressor-GlcR	unknown	unknown	gnl|CDD|224268
CP032698.1|AYG80850.1|3359241_3360102_-|Bifunctional-ligase/repressor-BirA	unknown	unknown	gnl|CDD|223417
CP032698.1|AYG80853.1|3362640_3362769_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80852.1|3361891_3362098_+|hypothetical-protein	unknown	unknown	gnl|CDD|379386
CP032698.1|AYG80865.1|3375522_3376140_-|hypothetical-protein	unknown	unknown	gnl|CDD|320678
CP032698.1|AYG80861.1|3370824_3371649_+|Purine-nucleoside-phosphorylase	unknown	unknown	gnl|CDD|236183
CP032698.1|AYG80847.1|3355833_3356967_-|Phytochrome-like-protein-cph2	unknown	unknown	gnl|CDD|128563
CP032698.1|AYG80862.1|3371707_3373354_+|putative-phosphomannomutase	unknown	unknown	gnl|CDD|100092
CP032698.1|AYG80854.1|3362809_3363421_+|Maf-like-protein	unknown	unknown	gnl|CDD|178901
CP032698.1|AYG80857.1|3366588_3367191_+|HTH-type-transcriptional-repressor-KstR2	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG80863.1|3373584_3374811_+|hypothetical-protein	unknown	unknown	gnl|CDD|379080
CP032698.1|AYG80864.1|3374848_3375484_-|hypothetical-protein	unknown	unknown	gnl|CDD|371225
CP032698.1|AYG80848.1|3357060_3357849_-|2,3-dehydroadipyl-CoA-hydratase	unknown	unknown	gnl|CDD|181069
CP032698.1|AYG80860.1|3369976_3370414_+|hypothetical-protein	unknown	unknown	gnl|CDD|372719
CP032698.1|AYG80851.1|3360253_3361861_+|putative-propionyl-CoA-carboxylase-beta-chain-5	unknown	unknown	gnl|CDD|227136

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80865.1|3375522_3376140_-|hypothetical-protein	gnl|CDD|320678	cd05829, Sortase_F, Sortase domain found in the class F family of sortases. Class F sortases are mainly present in Actinobacteria, Chlorobacteria and Firmicutes. Their functions are largely unknown.	1.96799e-49
CP032698.1|AYG80856.1|3364297_3366052_+|Biotin-carboxylase	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
CP032698.1|AYG80849.1|3357914_3359126_-|pH-sensitive-adenylate-cyclase	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	1.01681e-30
CP032698.1|AYG80851.1|3360253_3361861_+|putative-propionyl-CoA-carboxylase-beta-chain-5	gnl|CDD|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
CP032698.1|AYG80858.1|3367187_3368147_-|HTH-type-transcriptional-repressor-GlcR	gnl|CDD|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	4.14051e-83
CP032698.1|AYG80850.1|3359241_3360102_-|Bifunctional-ligase/repressor-BirA	gnl|CDD|223417	COG0340, BirA, Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism].	5.4584e-61
CP032698.1|AYG80852.1|3361891_3362098_+|hypothetical-protein	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	1.41842e-08
CP032698.1|AYG80848.1|3357060_3357849_-|2,3-dehydroadipyl-CoA-hydratase	gnl|CDD|181069	PRK07657, PRK07657, enoyl-CoA hydratase; Provisional.	8.76521e-70
CP032698.1|AYG80861.1|3370824_3371649_+|Purine-nucleoside-phosphorylase	gnl|CDD|236183	PRK08202, PRK08202, purine nucleoside phosphorylase; Provisional.	8.5872e-133
CP032698.1|AYG80847.1|3355833_3356967_-|Phytochrome-like-protein-cph2	gnl|CDD|128563	smart00267, GGDEF, diguanylate cyclase. Diguanylate cyclase, present in a variety of bacteria.	2.06576e-39
CP032698.1|AYG80862.1|3371707_3373354_+|putative-phosphomannomutase	gnl|CDD|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
CP032698.1|AYG80857.1|3366588_3367191_+|HTH-type-transcriptional-repressor-KstR2	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	2.97161e-10
CP032698.1|AYG80863.1|3373584_3374811_+|hypothetical-protein	gnl|CDD|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	0.000220534
CP032698.1|AYG80864.1|3374848_3375484_-|hypothetical-protein	gnl|CDD|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	8.40787e-06
CP032698.1|AYG80854.1|3362809_3363421_+|Maf-like-protein	gnl|CDD|178901	PRK00148, PRK00148, Maf-like protein; Reviewed.	7.9704e-95
CP032698.1|AYG80860.1|3369976_3370414_+|hypothetical-protein	gnl|CDD|372719	pfam13772, AIG2_2, AIG2-like family. This family is found in bacteria and metazoa.	8.3455e-24
CP032698.1|AYG80859.1|3368302_3369889_-|NAD(P)H-dehydrogenase-(quinone)	gnl|CDD|236112	PRK07845, PRK07845, flavoprotein disulfide reductase; Reviewed.	0

Protein sequences

>CP032698.1|AYG80856.1|3364297_3366052_+|Biotin-carboxylase
MRKVLIANRGEIAVRVARACRDAGIASVAVYADPDRDALHVRTADEAFALGGDTPAASYLDIAKVLAAAADSGADAVHPGYGFLSENAEFAQAVLDAGLTWIGPPPQAIRDLGDKVAARHIAQRAGAPLVAGTPDPVSGADEVVAFAREHGLPIAIKAAFGGGGRGLKVARTLEEVPELYDSAVREAVAAFGRGECFVERYLDKPRHVETQCLADTHGNVVVVSTRDCSLQRRHQKLVEEAPAPFLTEAQNAELYAASKAILKEAGYVGAGTVEFLVGADGTISFLEVNTRLQVEHPVTEEVTGIDLVREMFRIADGEELGYGDPVMRGHSIEFRINGEDPGRGFLPAPGTVTLFSPPTGPGVRLDAGVESGSVIGPAWDSLLAKLIVTGATREQALQRAARALAEFTVEGMATAIPFHRAVVADPAFTADPFRIHTRWIETEFVNEIPAFTAPADAESDEEPGRETVVVEVGGKRLEVSLPSSLGMTLARTAAAGGAKPKRRAAKKTGSAASGDTLASPMQGTIVKVAVEEGQEVKEGDLVVVLEAMKMEQPLNAHRAGTVKGLAAEVGASVSSGAMICEIKD
>CP032698.1|AYG80855.1|3363428_3363896_-|hypothetical-protein
MLRRPIAIVAALILFAEACGIVLVNWVLGLVAHNQNMSLAGIDPHAISVGAWVAGGLFGLFLAVCGVLLLIVGIRDRAPGRIARITLIACAVVHAVLAAFTVGLVGWGAFAYLMVVLALLVLVLLAYARERPVAKAGPAPEDGTPPAPNGAPAAA
>CP032698.1|AYG80854.1|3362809_3363421_+|Maf-like-protein
MAHMTAPRRLVLASQSPARLGLLRQAGLAPEVIVSGVDEDALSAPTPSELALVLAEAKADAVAARPEASGALVIGCDSVLELDGLALGKPADAEDATARWKSMRGRSGVLRTGHCVIDTATGGRTSATASTVVHFGEPTDAELAAYVASGEPLYVAGAFTLDGRSAPFIDSIEGDPGNVIGLSLPLLRTLLAELGVPITELWV
>CP032698.1|AYG80853.1|3362640_3362769_+|hypothetical-protein
MLWSDPDDKPPKELRDAQAMMRRAGLFLALAMVVAMIVVNIR
>CP032698.1|AYG80852.1|3361891_3362098_+|hypothetical-protein
MIKVVRGNPTPEELAAALAVVQARAAATASAASGAPEPPEGWSDPSRIARHALPRPGAHAWSRTYWPA
>CP032698.1|AYG80851.1|3360253_3361861_+|putative-propionyl-CoA-carboxylase-beta-chain-5
MSEPENAQSDATVDLHTTAGKLADLQRRIDEATHAGSARAIEKQHAKGKLTARERVELLLDEGSFVELDEFARHRSTNFGIEKNRPYGDGVVTGYGTVDGRPVCVYSQDFTIFGGSLGEVYGEKIVKVMDFALKTGCPVIGINDGGGARIQEGVVALGLFAEIFRRNVHASGVVPQISLIVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELGGARTHNTTSGVAHHMAGDEKDAIEYVKSLLSYLPSNNLSEPPAFPEEADLETSDEDRELDALIPDSANQPYDMHTAIEHVLDEGEFLETQALFAPNIITGFGRVEGYPVGIVANQPMQFAGCLDINASEKAARFVRTCDAFNVPVLTFVDVPGFLPGVDQEYGGIIRRGAKLIYAYAEATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIAAAAPEDQEATRAELIADYEDTLLNPYIAAERGYVDAVIMPSETRAHIVRGLRQLRTKRESLPPKKHGNIPL
>CP032698.1|AYG80850.1|3359241_3360102_-|Bifunctional-ligase/repressor-BirA
MTPPDASDSRWSDLDRPPLNATALRRALLRPDALWTSLDVVTATGSTNSDLAAKADGLAEGAVLVAEEQTAGRGRLDRRWSAPARSGLFFSVLLKPGASVPVERWGWLPLLTGVAVAGGLARAAGVETALKWPNDLLVTVDGAERKAGGILAERAGADGVVVGIGLNVTLRADELPVPGAGSLALAGAVSTDRDTLLRAVLRSIEEWYASWRTASGDPAACGLHEAYAAACATLGRTVRAELPGGQSVEGEAVAVDGDGRLVLATGEGVQRPVAAGDIVHLRPAAS
>CP032698.1|AYG80849.1|3357914_3359126_-|pH-sensitive-adenylate-cyclase
MTVDETRSGADAGSGPGDTPGGSGTPAQAAPSAYPTPHHAVDHTAEPTDDPLAIRLEQLILGADRRYTPFQAARTAGVSMELASRFWRAMGFADIGQAKALTEADVLALRRLAGLVEAGLLSEPMAVQVARSTGQTTARLAEWQIDSFLEGLTEPPEPGMTRTEVTYPLVELLLPELEEFLVYVWRRQLAAATGRVVQAADDEEMVDRRLAVGFADLVGFTRLTRRLEEEELGELVEAFETTAADLVAAHGGRLIKTLGDEVLFAADDAGTAAEISLRLIETMAGDETMPALRVGIAFGTVTTRMGDVFGTTVNLASRLTSIAPKDAVLVDGAFAEELARTGDAPVSEAQAAQDALAAEKEGEDFPPPAKYRFALQPMWQRPVRGLGVVEPWLLRRREVPNLS
>CP032698.1|AYG80848.1|3357060_3357849_-|2,3-dehydroadipyl-CoA-hydratase
MAEQRFGEFVVVRREGYVAELVLDRPKAMNAVSTEMARSIAAACEALGADRDARVTVVSSTNERAFCVGADLKERNSFSDAELVRQRPTARAAYTGVLELPMPTVAAVHGFALGGGFELALACDVIVADATAVVGLPEVSVGVIPGGGGTQLLPRRVGAARAAELVFTARRVEAVEARELGLVDVLAEDARTEALALAGRMAANSPVGLRAAKRAMRLGHGLDLRAGLEVEDAAWRSVAFSGDRAEGVAAFNEKRKPAWPGE
>CP032698.1|AYG80847.1|3355833_3356967_-|Phytochrome-like-protein-cph2
MGGEDARLRAVVSLAQAMAAAHTPRESWRAAALGARCALGGNFAALSVWERELGRLRVLVNAGERAHGEEEFPEDETYPVHQFPEITEFLHERWAGGGEPNAWVETAAAPPEGDVGYCHERVTALRRRGRGCCVVAPIVLHGRAWGELYVARPVGVPVFDAADADFATVLASVAAAGIAQTERLEEVRRLAFTDPLTGLANRRAVDMRLDEAVERHRADDSVVSLVVCDLNGLKRVNDTLGHAVGDRLLERFGSVLSLCGAKLPGALSARLGGDEFCLLSVGPGADEVVAVGEELCLRAGELELGEGVACGVASTGDPIGPVVSARRLFRLADAAQYRAKAARSARPVVAGRDGAVLRLAENPPRPPHDRRRFRGRG
>CP032698.1|AYG80857.1|3366588_3367191_+|HTH-type-transcriptional-repressor-KstR2
MDGNTGSPPRPRRADARRNHDRLLATARTAFAEHGTDTSLEDVARRAGVGIGTLYRHFPTRHALLSAVFQSEVEILLARSRELLDAEQPCTALIEWLRAIITHAGLYRGLARALMSASGDASSALARCSEPMREAGDALLVRAREAGSVRADVTIADLMQLTNAIALAAEQSPDDLELADRLLALTYRGLKGQPRPTGRA
>CP032698.1|AYG80858.1|3367187_3368147_-|HTH-type-transcriptional-repressor-GlcR
MFAAERRQLILEMVRANGAVSLRELARVVQTSEVTVRRDVRALEAEGLLDRRHGGAVLPGGFTRESGFPQKSHLATAEKTAIADLAAGLVEEGEAIVVGAGTTTQELARRLARVPGLTVVTNSLLVAQALAHANRVEVVMTGGTLRGSNYALVGSGAEQSLQGLRVSRAFLSGSGLTAERGLSTSNMLSASVDRALVQAAAEVVVLADHTKLGTDTMFQTVPTDVITRLVTDEPPGHDDRAATELQALADQGVQIAVAGPSGAPSGETAPGRPPRRDVPLPGQRRTHGPGAGPQLRSASGMGEPQGPGERARVADLRRR
>CP032698.1|AYG80859.1|3368302_3369889_-|NAD(P)H-dehydrogenase-(quinone)
MAAEWRPRGEDTGSVRDNEVRTAFPRGPAPDPRPGGQAGRDRHYEADFFVTRIVIIGGGPGGYEAALVGAQLGAEVTVVDCDGLGGASVLTDCVPSKTLIATAEVMTTFDSSYEELGILVADDTPPEEQSARVVGVDLGKVNRRVKRLALAQSHDITASVTRAGARVMRGRGRLAGPQGIDGTRDVIVTAADGTEEMLTCEAVLIATGGSPRELPDAQPDGERILNWTQVYDLDELPEELIVVGSGVTGAEFAGAYQALGSKVTLVSSRDRVLPGEDPDAAAVLEDVFRRRGMNVMARSRAESAKRVGDRVEVTLSDGRVISGSHCLMAVGAIPNTANMGLEESGVRLKESGHIWTDKVSRTSAPGVYAAGDVTGIFALASVAAMQGRIAMYHFLGDAVAPLNLKTVSSNVFTDPEIATVGYTQADVDAGKIDARVVKLPLLRNPRAKMQGIRDGFVKIFCRPGTGIIVGGCVVAPRASELIHPISIAVDNNLTVEQIANAFTVYPSLSGSIAEVARQLHTRKKAGEA
>CP032698.1|AYG80860.1|3369976_3370414_+|hypothetical-protein
MSLYAAYAGNLDPRLMTRRAPHSPLRGTGWLNGWRLTFGGEQMGWEGALATIVEAPRSQVFVALYDIAPLDEESMDRWEGVGLDIYRRMRVRVHTLDGEDAAWLYVLNGYEGGLPSARYLGELADAAESAGAPHDYVMELRKRPC
>CP032698.1|AYG80861.1|3370824_3371649_+|Purine-nucleoside-phosphorylase
MNASAIPDLLQDDPHAAADAAAARLRELTGAETHDVALVMGSGWAPAVDALGAPEAEFPVTELPGFPAPAVEGHGGKIRSYKIGTKRVLVFLGRTHFYEGRGVASVSHGVRTAVAAGCKTVVLTNGCGGLRDGMRPGQPVLISDHINLTATSPIIGANFVDLTDLYSPRLRALCKEVDETLEEGVYVQFPGPHYETPAEINMVRVLGGDLVGMSTVLEAIAAREAGAEVLGISLVTNLAAGLTGEPLNHEEVLQAGRDSAARMGELLTRVLDRI
>CP032698.1|AYG80862.1|3371707_3373354_+|putative-phosphomannomutase
MTQDLIARARAWLAEDPDSETRDELAKLIESSADAEHAAELAARFSGTLQFGTAGLRGELGAGPMRMNRSVVIRAAAGLAAYLKAKGQGDGLVVIGYDARYKSADFARDTAAVMVGAGLRATVLPRPLPTPVLAYAIRHLGAVAGVEVTASHNPPRDNGYKVYLGDGSQIVPPADAEIAAEIAAVASLHDVPRPESGWEVLGDEVLDAYLARTDAVLTAGSPRTANVVYTAMHGVGKDVLLAAFARAGFPEPVLVAEQAEPDPAFPTVAFPNPEEPGAMDLAFATARRVDPDVVLANDPDADRCAAAVKDRDGQWRMLRGDEVGALLAAHLVAKGVTGVFAESIVSSSLLGRIAEAAGLGYEETLTGFKWIARVEDLRYGYEEALGYCVDPEGVRDKDGITAALVLAELVSVLKEQGRTVLDLLDELALAHGLHATDQLSVRVEDLTVISNAMARLREQPPTALAGLAVTKAEDLTEGTEELPPTDGLRYYLEGARVIVRPSGTEPKLKCYLEVVVPVGSADELDAARARGAELLAGIKKDLAAAAGI
>CP032698.1|AYG80863.1|3373584_3374811_+|hypothetical-protein
MSPTAPPPATTTVRRGPVPGARRYPAERVPGGRPPVGERARTALRYAGPALLGHLAVRLLGVIVLARWTHLRHHGLWPVLAKSWDSNWYLGIAAHGYELTPPGTEEPSNLAFFPLYPVLVKAVAAVTPGSRASVALVLAVVFSLVAAGGVFAVGDRLHGRRTATVLTVLWAALPVGVVQWMGYTESLFTALTAWALYCALTGRWVWAGSLAALAGLTRPTGVAIAAAVSLTALAALVRARRLAWRPVLGGLLAPLGWCSYVAWVGLRVGRWDGYFAVQKLWANEWDGGAGTLREMRDLLVYANRPPLFLVVVTLVLLVSGALYVLSLADRQPLVLLVFTGALLLVVLGSGGVYFPRARFLLPGFPLLLPVALALSRARRTVTALVLGAAAVSSAWLGAYMLMVWPGPP
>CP032698.1|AYG80864.1|3374848_3375484_-|hypothetical-protein
MTSPTPPAEPAYADRTYRSAAGIAGGALLLAIGLWLGVDAVIQGHGNAPWLSLAVLLCAVPLIVAFSFRPAVFAGADRLIVRNPFRTITLPWASVADVRAGYSSEVFDQSGGKYQLWAIPVSLRQRKRAARRQVRDATVDGQIGTSVTADVTDTKARMAPTDQSVLTLRELAEQGASREGAQGPVSIRWAYEVIAPAVAGAVLFVVLLAIG
>CP032698.1|AYG80865.1|3375522_3376140_-|hypothetical-protein
MSRTRAARSAATALVLLALGASAAGCGSGAAKPATPPPNISPASAAPATPKAATALPASKPVRVRIPAAGVDTGPILDLGLAADGTVEVPSVADADRIGWYDKGVTPGQTGPAVLIGHFDTVKGPAVLKNVSKVKVGDLVTVDRADGKPARFAVRALEQVDKKTFPTQKVYGNTDRPELRIITCGGELTGGHRPDNIIVYADLVA
>CP032698.1|AYG80866.1|3376286_3377399_-|hypothetical-protein
MSTYARTPLRAAIATAALAGALLAPAAAFAATPGQAPATTSCHVTKSVASERLGMTVTLTNDLADGPKAELKDGNGKVVATVDRAHPTDLSAGIKLEAATGGKAVFFQRSQGGDTAWKSQPFPALPKECAATPGVVTYKLVNGETVAVGKLGTGHYRAEFVTNGKVVLILTTGGEDVDGYVHGMHVVLNATTGKVTSEFTDGRAGCTVTKVVPSVFGAGMSVKLTNSVQGPKAVLRDASLKALATADRAHPVDGRYGVRIDGANTATPKLGQRTQGGTMPYRYTAFPKLPAGCANTAPAKNPATTPATVVNTPVQNGGQTTVVPKGAVAAGAEFKQGGEGKGLMIAGAAGAVVAAGAGVFVLRRRAGSTN

Crispr_ID: CP032698_20

• CRISPR_ID: CP032698_20
• CRISPR_location: 3444567-3444650
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_20

Consensus_repeat	Method
TGCTCGCGCAGTTCCCCGCGCCCCT	CRISPRCasFinder

spacers of CP032698_20

>20.1|3444592|34|CP032698|CRISPRCasFinder
GAAAACCCGTTTTCGTCTGCGGGCCGCAGGTGGC

CRISPR arrays and Neighbor proteins around CP032698_20

CRISPR arrays

The CRISPR arrays of CP032698_20

>merge|CP032698|20|3444567-3444650|CRISPRCasFinder
TGCTCGCGCAGTTCCCCGCGCCCCTGAAAACCCGTTTTCGTCTGCGGGCCGCAGGTGGCTGGTCGCGCAGTTCCCCGCGCCCCT

>CP032698|20|16|3444567-3444650|CRISPRCasFinder
TGCTCGCGCAGTTCCCCGCGCCCCT	GAAAACCCGTTTTCGTCTGCGGGCCGCAGGTGGC
TGGTCGCGCAGTTCCCCGCGCCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80929.1|3439644_3440184_-|Putative-decaprenylphosphoryl-5-phosphoribose-phosphatase	unknown	unknown	gnl|CDD|239489
CP032698.1|AYG80941.1|3452677_3453541_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80926.1|3437358_3438258_-|Inner-membrane-protein-YhjD	unknown	unknown	gnl|CDD|377085
CP032698.1|AYG80930.1|3440371_3441757_+|Decaprenylphosphoryl-beta-D-ribose-oxidase	unknown	unknown	gnl|CDD|223354
CP032698.1|AYG80925.1|3436049_3437390_+|D-alanyl-D-alanine-carboxypeptidase-DacD	unknown	unknown	gnl|CDD|224600
CP032698.1|AYG80932.1|3442658_3443237_-|Putative-phosphoesterase-YjcG	unknown	unknown	gnl|CDD|379265
CP032698.1|AYG80931.1|3441873_3442629_+|Decaprenylphosphoryl-2-keto-beta-D-erythro--pentose-reductase	unknown	unknown	gnl|CDD|181162
CP032698.1|AYG80935.1|3446158_3447475_+|Ornithine-aminotransferase	unknown	unknown	gnl|CDD|179736
CP032698.1|AYG80940.1|3452269_3452536_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80942.1|3453612_3453744_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80939.1|3451030_3452215_-|Putative-acid--amine-ligase-YgiC	unknown	unknown	gnl|CDD|367631
CP032698.1|AYG80934.1|3444754_3446026_-|Serine-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234571
CP032698.1|AYG80938.1|3449034_3450810_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80924.1|3435706_3435979_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80936.1|3447481_3448621_-|IgA-FC-receptor	unknown	unknown	gnl|CDD|223021
CP032698.1|AYG80927.1|3438245_3438710_-|hypothetical-protein	unknown	unknown	gnl|CDD|377229
CP032698.1|AYG80933.1|3443374_3444442_-|Tryptophan--tRNA-ligase	unknown	unknown	gnl|CDD|234866
CP032698.1|AYG80943.1|3453799_3454159_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80937.1|3448628_3449033_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80928.1|3438706_3439648_-|Decaprenyl-phosphate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|237058

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80929.1|3439644_3440184_-|Putative-decaprenylphosphoryl-5-phosphoribose-phosphatase	gnl|CDD|239489	cd03395, PAP2_like_4, PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.66241e-17
CP032698.1|AYG80926.1|3437358_3438258_-|Inner-membrane-protein-YhjD	gnl|CDD|377085	pfam03631, Virul_fac_BrkB, Virulence factor BrkB. This family acts as a virulence factor. In Bordetella pertussis, BrkB is essential for resistance to complement-dependent killing by serum. This family was originally predicted to be ribonuclease BN, but this prediction has since been shown to be incorrect.	1.40842e-34
CP032698.1|AYG80925.1|3436049_3437390_+|D-alanyl-D-alanine-carboxypeptidase-DacD	gnl|CDD|224600	COG1686, DacC, D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane].	6.38376e-45
CP032698.1|AYG80932.1|3442658_3443237_-|Putative-phosphoesterase-YjcG	gnl|CDD|379265	pfam13563, 2_5_RNA_ligase2, 2'-5' RNA ligase superfamily. This family contains proteins related to pfam02834. These proteins are likely to be enzymes, but they may not share the RNA ligase activity.	2.40053e-24
CP032698.1|AYG80931.1|3441873_3442629_+|Decaprenylphosphoryl-2-keto-beta-D-erythro--pentose-reductase	gnl|CDD|181162	PRK07904, PRK07904, decaprenylphospho-beta-D-erythro-pentofuranosid-2-ulose 2-reductase.	2.71751e-87
CP032698.1|AYG80935.1|3446158_3447475_+|Ornithine-aminotransferase	gnl|CDD|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
CP032698.1|AYG80939.1|3451030_3452215_-|Putative-acid--amine-ligase-YgiC	gnl|CDD|367631	pfam03738, GSP_synth, Glutathionylspermidine synthase preATP-grasp. This region contains the Glutathionylspermidine synthase enzymatic activity EC:6.3.1.8. This is the C-terminal region in bi-enzymes. Glutathionylspermidine (GSP) synthetases of Trypanosomatidae and Escherichia coli couple hydrolysis of ATP (to ADP and Pi) with formation of an amide bond between spermidine and the glycine carboxylate of glutathione (gamma-Glu-Cys-Gly). In the pathogenic trypanosomatids, this reaction is the penultimate step in the biosynthesis of the antioxidant metabolite, trypanothione (N1,N8-bis-(glutathionyl)spermidine), and is a target for drug design. This region, the pre-ATP grasp region, probably carries the substrate-binding site.	4.30114e-179
CP032698.1|AYG80934.1|3444754_3446026_-|Serine-hydroxymethyltransferase	gnl|CDD|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
CP032698.1|AYG80930.1|3440371_3441757_+|Decaprenylphosphoryl-beta-D-ribose-oxidase	gnl|CDD|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	7.06821e-46
CP032698.1|AYG80936.1|3447481_3448621_-|IgA-FC-receptor	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	1.54795e-08
CP032698.1|AYG80927.1|3438245_3438710_-|hypothetical-protein	gnl|CDD|377229	pfam04138, GtrA, GtrA-like protein. Members of this family are predicted to be integral membrane proteins with three or four transmembrane spans. They are involved in the synthesis of cell surface polysaccharides. The GtrA family are a subset of this family. GtrA is predicted to be an integral membrane protein with 4 transmembrane spans. It is involved is in O antigen modification by Shigella flexneri bacteriophage X (SfX), but does not determine the specificity of glucosylation. Its function remains unknown, but it may play a role in translocation of undecaprenyl phosphate linked glucose (UndP-Glc) across the cytoplasmic membrane. Another member of this family is a DTDP-glucose-4-keto-6-deoxy-D-glucose reductase, which catalyzes the conversion of dTDP-4-keto-6-deoxy-D-glucose to dTDP-D-fucose, which is involved in the biosynthesis of the serotype-specific polysaccharide antigen of Actinobacillus actinomycetemcomitans Y4 (serotype b). This family also includes the teichoic acid glycosylation protein, GtcA, which is a serotype-specific protein in some Listeria innocua and monocytogenes strains. Its exact function is not known, but it is essential for decoration of cell wall teichoic acids with glucose and galactose.	1.45445e-20
CP032698.1|AYG80933.1|3443374_3444442_-|Tryptophan--tRNA-ligase	gnl|CDD|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	0
CP032698.1|AYG80928.1|3438706_3439648_-|Decaprenyl-phosphate-phosphoribosyltransferase	gnl|CDD|237058	PRK12324, PRK12324, decaprenyl-phosphate phosphoribosyltransferase.	9.09886e-109

Protein sequences

>CP032698.1|AYG80933.1|3443374_3444442_-|Tryptophan--tRNA-ligase
MASTRPPVAHHHPQGNGFAMQQRPRVLSGIQPTAGSFHLGNYLGAVRQWVALQESHDAFYMVVDLHAITVPQDPAELRANTRLAAAQLLAAGLDPEHCTLFVQSHVPEHAQLAWIMNCLAGFGEASRMTQFKDKSAKQGAGNATVGLFTYPILQVADILLYQAHQVPVGEDQRQHIELTRDLAERFNGRFGETFTVPAPYILKETAKIYDLQDPSIKMSKSASTPKGLINLLDEPKTTAKKVKSAVTDTDTVIKYDTENKPGVSNLLTIYSTLTGRTIAALEAEYEGKMYGALKTDLAEVMVEFVTPFRARTQQYLDDPETLDSLLAKGAEKARAVAAETLATAYDKVGLLPAKH
>CP032698.1|AYG80932.1|3442658_3443237_-|Putative-phosphoesterase-YjcG
MGTVTLGVSIAVPEPYGSLLQERRAGFGDPAAHGIPTHITLLPPHEVQRECLPEIEAHLASVAAAGRAFELRLEGTGTFRPLSPVVFVKVRRGAGDCAWLQQRVRDEAGPLVRELQFPYHPHVTVAHGISEEAMDLAHESLAQFSASWTCGGFALYEQGADGVWRKLREYPFGVGALGVPAQGASLDHPSLR
>CP032698.1|AYG80931.1|3441873_3442629_+|Decaprenylphosphoryl-2-keto-beta-D-erythro--pentose-reductase
MKDAFGMPQSLLVLGGTSEIGLATARRLVARRTRTVWLAGRPSAALDAAAAELRALGPDVHTVAFDALDPAAHEVALGKVFAEGDIDLVLLAFGVLGDQVHDEKEPLAAVRVAGTNYTGAVSAGLICAKALQTQGHGSLVVLSSVAGERARRGNFIYGSSKAGLDAFAQGLGDALHGTGVHVMVVRPGFVRTRMTAGLPEAPLATTPEAVALAIEAGLRRRAELVWVPGALRMVMSALRHVPRAVFRRLPV
>CP032698.1|AYG80930.1|3440371_3441757_+|Decaprenylphosphoryl-beta-D-ribose-oxidase
MSAETTPDAALAPLGPPTSVSGWGRTAPSAARLLRPRSYEEAAAAVLACGARGTIARGLGRAYGDAAQNAGGAVLDMTGLDRIRSVDADAGVVVCDAGVSLHRLMEVLLPLGWFVPVTPGTRQVTVGGAIGADIHGKNHHVSGSFARHVRELDLLTADGTVRTLTPDSELFDATTGGMGLTGVILSATLQLLPVRTSLMTVDTERALDLDDLMTRLESGDHRYRYSVAWVDLLARGAKTGRSVLTRGEHAPLDMLPPRARRAPLDFRPRSLPAAPAFLPEGLLGRGSVSAFNALWYRRAPHHRTGELQRISTFFHPLDGVPHWNRVYGRGGFVQYQFVVGYGQEDTLRAIVHRLSRHRCPSFLAVLKRFGDADAGWLSFPLPGWTLALDIPARLPGLAALLDELDERVAGAGGRVYLAKDARMRPELVEHMYPWLPRFRALRRELDPRGVFRSDMSRRLGL
>CP032698.1|AYG80929.1|3439644_3440184_-|Putative-decaprenylphosphoryl-5-phosphoribose-phosphatase
MQKPSCTDADQRLLAALRDCANEPRVAAAARALSFAGEHGALWLAAGLAGAVADRDRRGAWLRATALVAAAHLASMGVKRVVRRPRPHLPAAEPLVRTAGRHSFPSSHASSAAAAAVAYGALRPAGAHLVGPLAAAVCVSRVVAGVHYPSDIAAGALLGGVTARAGAAWMRKPLEAGRR
>CP032698.1|AYG80928.1|3438706_3439648_-|Decaprenyl-phosphate-phosphoribosyltransferase
MTEPGTVLLDEARTPALHRLLALPGGLLRTARPRQWIKNVLVLAAPAAAGRLLSPHDIGQLALVFCLFTASAAAVYLINDAQDAEADRAHPDKRHRPVAAGRVPVGAAYATGAALAVLTPPLAALTCNAMTATLLTAYVLMQLAYCVKLKHVLVVDLVVVTTGFLMRAMIGGVALGIPLSRWFLITAGFGALFMVAAKRYSEALRMEGSGAATRSLLDAYTTGYLRFVWQLAAGVAVLAYCLWALEAGGVARGSLLPWRQLSMVPFIGAILRYAVFADRGSAGAPEDVVLHDRALAVIGAVWVALYALAVADL
>CP032698.1|AYG80927.1|3438245_3438710_-|hypothetical-protein
MSVAKAELIGFALAGSCAYAADLVLFVGLRSGLHWDPIAAKSLSFVAGCTVAYLGNAFGTYRGRRAGRREYAVFFAVNIAGALVQLLCIALSHYGLGFTSPRADTLSGAVFGMALATCLRFWGTRTLVFGPAPRGPHQDRHSQAGEGSRTSWTG
>CP032698.1|AYG80926.1|3437358_3438258_-|Inner-membrane-protein-YhjD
MDWLKKLPVVGPWITRLMRTHAWRSYERLDRVYWSRLAAAITFVSFLALFPLLTVGAAVAAALLSTDQVHKLQNTLAEQVPGISDQLDLQALIDNAGTVGVVAGALLLFTGIGWVGQMRGCLRVVWDMEEADEGENPILRKLKDGGVLLGLGGAGLASWAASSIGSTAVGWTAERLGIDEGGAGGVLLRVAAIAVAVLADFLLLLYVLTLLPGVSPQRRRLMVAALLGAVGFELLKMLLGGYMKGVAAKSMYGAFGVPIALLLWINFTAKLLLFCAAWTATPSKEDDPDLIASEEASAD
>CP032698.1|AYG80925.1|3436049_3437390_+|D-alanyl-D-alanine-carboxypeptidase-DacD
MIGSMVAACTFSNVSALNVKKSAAPRRAPRPRRPARLALSVALAAAAVLPALAPAAAVALPRDDKPAASATPGAPGKRNDAPPPGMSTVGGAPLGEAGTQVRLGAGAPVLPQQVTGRSWIVADAESGQVLAAHNAHWRLPPASTLKMLFADTVLPKFPRDQQHTVLAQDLAGLGAGSSMVGVKENLAYSVHDLWLGVFLRSGNDAVHVLSSMNGGVAKTVQDMQARADELQALDTRVVSPDGYDMPGQVSSAYDLTLFARSGLQNKDFREYCATATAKFPGAEGKDKKREMSEIQNTNRLLTGDVGLNPYKGIAGVKNGNTTNAGATFTGVAERGGKVLLVTVMNPESTESQAVYKEAARLLDWGFAASGKVTPVGELVPPKSATTGKGTATGGAQEVVKKRLDSAAAAQGESGGVGIALGVAGGALIVVAGAVFLINRRWPLRRR
>CP032698.1|AYG80924.1|3435706_3435979_-|hypothetical-protein
MKLSRPLSWFLLAFGAWSWVIWTTFVKNLWKDGSGLAFDAAGDPTAYFWVHLLLAVTSFLLGTGVGAIGFRSLRHLRREQAATESSVTLG
>CP032698.1|AYG80934.1|3444754_3446026_-|Serine-hydroxymethyltransferase
MSLPLSHPALLAADPELAALVAAEERLQSDTLRLIPSENYVSTAVLEASGTVLQNKYSEGYPGRRYYEGQQNIDKVEALAVDRAKALFGVEHANVQPYSGSPANLAVYLAFAEPGDTVMGMALPMGGHLTHGWGVSATGKWFRGVQYGVRADTGRVDLDEVRDLALKERPKLIFCGGTALPRTIDFAAFAEIAREVDAVLVADVAHIAGLIAGGAHPSPAPYADVISTTTHKTLRGPRGAMLMSRASHAKAIDKAVFPGLQGGPHNQTTAAIAVALHEAAQPAFCAYAHQVVANAKALAEALLARGFDLVSGGTDNHLILMDLTSRGVSGKVAAKGLDRAGVVVNYNTVPYDPRKPFDPSGIRIGTPALTSRGLGVEHVAMVAEWIDRGVAAAGAGDEGALSAIRQEVMALLTTHPAPGLPQS
>CP032698.1|AYG80935.1|3446158_3447475_+|Ornithine-aminotransferase
MTPYGKVSASGIRATIEKGTTDAPCRMTIGEPVSTHAATEDAIRSAEAHSAHNYHPLPVVVASAEGAWMTDVEGRRYLDMLAGYSALNFGHGNRRLIDAAKAQLERVTLTSRAFHHDRFAEFCTRLAELCGKDMVLPMNTGAEAVETAVKTARKWGYRVKGVPDGTAKIVVARDNFHGRTTTIVSFSTDPEARADYGPYTPGFEIVPYGDLEAMRAAVTDNTVAVLLEPIQGEAGVLVPPPGYLAGVRELTRERNVLFMADEIQSGLGRTGKTFACEHEGVVPDVYILGKALGGGVVPVSAVAASSEVLGVFRPGEHGSTFGGNPLACAVALEVIAMLRTGEYQQRATELGDHLHRELGLLTGTGAVEAVRGRGLWAGVDIDPSHGTGRQISERLMERGVLVKDTHGSTIRIAPPLVISKEDLDWGLDQLRAVLAQGA
>CP032698.1|AYG80936.1|3447481_3448621_-|IgA-FC-receptor
MTGGADEVRWNAATQKWETVRGGSTRPPTPPGPPAPETPDAGPVPPAPTTPPPPAPPAPGPRVPPLAPGFDALDPYDPYDTGGEDPYRTGGPEDPYRTGGPEDPYRTGGPEDPYRTGGPEDPYRTGGPFPRFPQAPELAEPPASPSRRVPVAVVVGLVFVVAAAGAGGGWLLARGGPDRPAATVSSPAATPRSGAPERTGDGRGGASASPSSASPSPSATVPAGFQLAQDPRGFRLYVPQGWTRQDQGDKGVFYNSPDGARLIQVYLVSEAGLSPYDALKGTSGTLATTHTGYREISLGRDATVPAGATQGARLVYAYDHTTLGHRRQVVDYAFLTPGGRHYAVLSAAPATAWPEQEQTLRAALSGFCEGSDCPSPSAG
>CP032698.1|AYG80937.1|3448628_3449033_-|hypothetical-protein
MTMPGDDSAPPRPPRDTGERSVHISGVTGSVSVGDHNTVHSVYRAGAAGDEAHRQLLQSIVEFRAGLAQLVRNDQTRALDAELADTEEEIRDQGRATPGRLARLGELLAGATALTGLLASGQGLVERVTELVGM
>CP032698.1|AYG80938.1|3449034_3450810_-|hypothetical-protein
MTQAQVPQQAQPPGPEPGGLPPVHPSRSEATRLMAAGTYLDAEYRDAVIDELYVHEERVVAPSLGFDAARVLAHALRARTLELAWSLGILFLWVLGAVVTRSAFLLVLGPCLQLGIARFVRGGAATAPWYRTIPAFLLRWWARVLLAMFAVVVLLSLLQGSDPSVTNSPSRHGSYGDGVDAFGGFSEGGNTVPGFVAGPARLLGGAAFDAADRGFGPGLAWGIVACFAVIALCVCLQRVQFARIMANELSPQGFQDVAADPAQRVDNGRLHRLAALIRAEQHAPLAVYRSDAPFRGAGEAFEPWSVSIQLRPRASLGEKSPARVSNAEILRIVEPLVTRLRVPAPAAPAEAHAVRDRLRQLEVTEYLFLPVDGLPSRTHAPYGGGDVEQHRAAALEEGGEARRHFLRIRVGGWEEHLVTTVFVRVHTQGGMLVLEIAPHVLSPLREDFLRADRTAQNFACRTPLGKAAWALARTPRSPVGALVVVGRALVSLWHRLTGGYARALPDGPARSIRELAAAPDASLFQAMDYRRYVKSIEDRVTSGVRSALYEAGYDTGQFEQKIINVTQGGVMIENARGAISVGDHNTVRNEG
>CP032698.1|AYG80939.1|3451030_3452215_-|Putative-acid--amine-ligase-YgiC
MERHHIQPRPDWQRTVEEQGVIYPLTRYPDDSLRPYWEESAYYSFTLPEVEALEETVEELHAMCLAAAAHIVERGRFADLGIMDGRLADLVAESWRRRAELPSLYGRFDLRYDGTGPAKLLEYNADTPTSLVEAASAQWFWMEERFPGADQWNSLHERLVAAWRRQARMLPPGPVHFAHSDGDELGEDLMTVAYLRETAEQAGLDTEALSVESIGWDSITGRFVDEKLRFIRSCFKLYPWEWLASDAFGPQVLDTLDNGGGTGTTCWIEPAWKMLLSNKALLAVLWELYPGHPNLLPAYLDGPRDLVDGPGYVAKPLLGREGAGVTLHPPGSAPAQRPEEACCYQELAPLPDFEGNRVVLGAWVVEDEAAGLGIRESAGLVTDGYARFLPHVIR
>CP032698.1|AYG80940.1|3452269_3452536_-|hypothetical-protein
MRRFRSTTVVLGGMGVLAATLTACSDEPDRRCVNPVTYKELPKYECKSGGSGQYYYGGSSRGGKVSGGSFDKSGVSRGGFGHEGSGGG
>CP032698.1|AYG80941.1|3452677_3453541_+|hypothetical-protein
MICALASAVCFGTATVLQAAATRAAEPGSGAGAGSGVDAALLLRAVRQWRYVVGLALDGLGFVFQVLALRSVPIYAVGAALAASLAVTAVVAARVLKVRLSGTEWAAVAVVCAGLALLALSSGAEGDDRGPASLPWWLLGVAGAVLAAGAAGGRLPDRARALVLGLGAGCGFGVVEVAVRLIDDPFDLTNPALYALLLGGGAAFLLLTSALSRGSVTTATAGMVIGETIGPALVGVAWLGDRTRDGLGWLTVTGFAVAVAGALALARFGEAPAAAGAEPPRQDAEEH
>CP032698.1|AYG80942.1|3453612_3453744_+|hypothetical-protein
MPVSVHTVPGVPWLGVYVTDRAHELGPSNTWARAVLVPCGLAA
>CP032698.1|AYG80943.1|3453799_3454159_-|hypothetical-protein
MQHENGRIFREAWISGVKKHYPGEPKPGYITPWEETPEWEREAAAAVSAQVSNFVGVSHRNTSKLSREQKGRFVALCWIAQIHKHFEDPKPSYVADWPELPEWQQQTDADIFEAIERTQ

Crispr_ID: CP032698_21

• CRISPR_ID: CP032698_21
• CRISPR_location: 3487068-3487151
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_21

Consensus_repeat	Method
GGATCGCGCAGTTCCCCGCGCCCCT	CRISPRCasFinder

spacers of CP032698_21

>21.1|3487093|34|CP032698|CRISPRCasFinder
GAAAACCCGTTCTCATCTGCGGACCGTGCGTGGC

CRISPR arrays and Neighbor proteins around CP032698_21

CRISPR arrays

The CRISPR arrays of CP032698_21

>merge|CP032698|21|3487068-3487151|CRISPRCasFinder
GGATCGCGCAGTTCCCCGCGCCCCTGAAAACCCGTTCTCATCTGCGGACCGTGCGTGGCTGGTCGCGCAGTTCCCCGCGCCCCT

>CP032698|21|17|3487068-3487151|CRISPRCasFinder
GGATCGCGCAGTTCCCCGCGCCCCT	GAAAACCCGTTCTCATCTGCGGACCGTGCGTGGC
TGGTCGCGCAGTTCCCCGCGCCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG80974.1|3485426_3487028_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80981.1|3495564_3496644_+|putative-endopeptidase	unknown	unknown	gnl|CDD|366353
CP032698.1|AYG80966.1|3473154_3475038_-|hypothetical-protein	unknown	unknown	gnl|CDD|223021
CP032698.1|AYG80969.1|3477691_3478870_-|Succinate--CoA-ligase-[ADP-forming]-subunit-beta	unknown	unknown	gnl|CDD|234813
CP032698.1|AYG80978.1|3490991_3493487_-|ATP-dependent-DNA-helicase-UvrD1	unknown	unknown	gnl|CDD|273429
CP032698.1|AYG80965.1|3472320_3473136_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
CP032698.1|AYG80980.1|3494861_3495215_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80983.1|3498006_3498687_-|Oxygen-regulatory-protein-NreC	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG80977.1|3489199_3490915_+|Glycyl-glycine-endopeptidase-LytM	unknown	unknown	gnl|CDD|366703
CP032698.1|AYG80968.1|3476784_3477669_-|Succinate--CoA-ligase-[ADP-forming]-subunit-alpha	unknown	unknown	gnl|CDD|180194
CP032698.1|AYG80979.1|3493688_3494846_+|putative-endopeptidase	unknown	unknown	gnl|CDD|366353
CP032698.1|AYG80975.1|3487287_3487701_-|Pivalyl-CoA-mutase-small-subunit	unknown	unknown	gnl|CDD|239022
CP032698.1|AYG80971.1|3480254_3482687_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG80967.1|3475211_3476684_+|hypothetical-protein	unknown	unknown	gnl|CDD|132028
CP032698.1|AYG80970.1|3479100_3480255_-|hypothetical-protein	unknown	unknown	gnl|CDD|283431
CP032698.1|AYG80973.1|3483935_3485312_+|hypothetical-protein	unknown	unknown	gnl|CDD|309540
CP032698.1|AYG80972.1|3482683_3483820_-|hypothetical-protein	unknown	unknown	gnl|CDD|336785
CP032698.1|AYG80982.1|3496739_3497876_-|hypothetical-protein	unknown	unknown	gnl|CDD|223700
CP032698.1|AYG80976.1|3488105_3488927_+|Extracellular-esterase-EstB	unknown	unknown	gnl|CDD|224001
CP032698.1|AYG80984.1|3498683_3499991_-|hypothetical-protein	unknown	unknown	gnl|CDD|226951

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG80979.1|3493688_3494846_+|putative-endopeptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	1.65108e-29
CP032698.1|AYG80966.1|3473154_3475038_-|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	5.10656e-08
CP032698.1|AYG80969.1|3477691_3478870_-|Succinate--CoA-ligase-[ADP-forming]-subunit-beta	gnl|CDD|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
CP032698.1|AYG80978.1|3490991_3493487_-|ATP-dependent-DNA-helicase-UvrD1	gnl|CDD|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
CP032698.1|AYG80965.1|3472320_3473136_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000165087
CP032698.1|AYG80981.1|3495564_3496644_+|putative-endopeptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	1.62245e-35
CP032698.1|AYG80983.1|3498006_3498687_-|Oxygen-regulatory-protein-NreC	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.14272e-55
CP032698.1|AYG80970.1|3479100_3480255_-|hypothetical-protein	gnl|CDD|283431	pfam05762, VWA_CoxE, VWA domain containing CoxE-like protein. This family is annotated by SMART as containing a VWA (von Willebrand factor type A) domain. The exact function of this family is unknown. It is found as part of a CO oxidising (Cox) system operon is several bacteria.	1.61129e-50
CP032698.1|AYG80982.1|3496739_3497876_-|hypothetical-protein	gnl|CDD|223700	COG0627, COG0627, Predicted esterase [General function prediction only].	0.000163999
CP032698.1|AYG80975.1|3487287_3487701_-|Pivalyl-CoA-mutase-small-subunit	gnl|CDD|239022	cd02071, MM_CoA_mut_B12_BD, methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom with a group attached to a neighboring carbon atom. This family is present in both mammals and bacteria. Bacterial members are heterodimers and involved in the fermentation of pyruvate to propionate. Mammalian members are homodimers and responsible for the conversion of odd-chain fatty acids and branched-chain amino acids via propionyl CoA to succinyl CoA for further degradation.	8.79673e-65
CP032698.1|AYG80977.1|3489199_3490915_+|Glycyl-glycine-endopeptidase-LytM	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.74191e-33
CP032698.1|AYG80967.1|3475211_3476684_+|hypothetical-protein	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	3.51958e-10
CP032698.1|AYG80968.1|3476784_3477669_-|Succinate--CoA-ligase-[ADP-forming]-subunit-alpha	gnl|CDD|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
CP032698.1|AYG80973.1|3483935_3485312_+|hypothetical-protein	gnl|CDD|309540	pfam04434, SWIM, SWIM zinc finger. This domain is found in bacterial, archaeal and eukaryotic proteins. It is predicted to be organized into two N-terminal beta-strands and a C-terminal alpha helix, thus possibly adopting a fold similar to that of the C2H2 zinc finger (pfam00096). SWIM is thought to be a versatile domain that can interact with DNA or proteins in different contexts.	0.000210313
CP032698.1|AYG80972.1|3482683_3483820_-|hypothetical-protein	gnl|CDD|336785	pfam07728, AAA_5, AAA domain (dynein-related subfamily). This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.	5.13758e-40
CP032698.1|AYG80976.1|3488105_3488927_+|Extracellular-esterase-EstB	gnl|CDD|224001	COG1075, LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only].	9.33675e-22
CP032698.1|AYG80984.1|3498683_3499991_-|hypothetical-protein	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	4.36387e-23

Protein sequences

>CP032698.1|AYG80974.1|3485426_3487028_+|hypothetical-protein
MTRATIEDVGGGPHSWEELVTAALLGTDRRPAVGPPGELLDAAATQTLRRRAGLVPAVAAERPSAAPPDERPELPDAARRRLALLLADRSAPAHAGGRRGSAPDLGELLPQWLALANERGLRAPAALLPTLLDAARARTDVRPQALAFAGPRGVWLAGLNPEWRFALRGGSGSALLPDPKDTASVQLLWDEGLFAERVALLGAVRADDPDAARALLATSWATERAEDRLLFLDSLRAGLSTADEPFLEQALADRSRNVRATAAELLSALPASALAGRMAARAASCVSLDRTGDEAVISVEAPHECDAAMQRDGVVPRPPTGRGERSWWLGQLVESAPLGTWPRRLGGRTVAAIVALPVADDWGDELHAAWCRAAVRQRDPEWARALLGAPAAPPGEGAGTASLAERAKLLSVLAEPERADWVARFISAHGLSEAFQLLGVCVVPWAEALGRAVVDALEIARDAGSYPWSFSGVMGLAERCLDPAEAGRLEGLTATPPEGEGASPGAGGYWAEAFQRLVATLRLRETMHTELTP
>CP032698.1|AYG80973.1|3483935_3485312_+|hypothetical-protein
MVARTFGDMTQQGVRWTAEQVLALAPDDASRKAGSRLGTAGPWSESGCDGSGAVWSLCKGSGSRPYRTVLDTSGPAYQCSCPSRKFPCKHAVGLMLLWSADEQSVPDGTAPDWAEQWLAGRRARAHQKPLGPTGATAKPVDAEAARRRAEKRAERITAGTTELEQRLADLLRGGLAAAERPGYGLWEETAARMVDAQAPGLAARVRELGAIPGSGPGWPARLLEECALMHLLDRAWLGRDTLPEPLTATVRSRVGVPAAAQGPPVRDHWQVLAQYDTADAKLTTRRVWLYGRDSGRSALILDYGAAGRAPELALPVGLTIDAEVTPYPGGGQSRAALGERYGTPTATEGPPPGGTVTEAAERYGRALLDDPWLASCPATLDAVIPIPPKDGDDTWQLADPAAELALPIATTTTSRAALWKLAAVSGGAPVTVFGECGHRGFTPLTVWPAGGREGVALT
>CP032698.1|AYG80972.1|3482683_3483820_-|hypothetical-protein
MTVSEIESETTGSHAEAAVEEALRPHAEQAFAGELAALAAADDRPRPARWRLSPWAVATYLLGGTLPDGTVITPKYVGPRRIVEVAVTTLATDRALLLLGVPGTAKTWVSEHLAAAVSGDSTLLVQGTAGTPEEAVRYGWNYAQLLAHGPSRAALVPSPIMRAMADGMTARVEELTRIPADVQDTLITILSEKTLPIPELGSETQAVRGFNLIATANDRDRGVNELSSALRRRFNTVVLPLPATAEAEVDIVSRRVDQLGRSLDLPAVPDGMTEIHRVVTVFRELRDGVTADGRTKLKSPSGTLSTAEAISVVTGGLALAAHFGDGVLRAGDVAAGILGAVVRDPAADRVIWQEYLETVVRERDGWKDFYRACREVSA
>CP032698.1|AYG80971.1|3480254_3482687_-|hypothetical-protein
MTARACARGPLLLGVRHHGPGSARAVLAALEAARPRAVLIEGPPEGDALLDLAADEAMRLPVALLAHVVDDPGRAAFWPMAEFSPEWVAIRWALAHGARVRFIDLPAAHSLAAGEEAEPEDGGPRIDPVRALAETAGYDDPERWWEDVVEHRDAAADPAAPFAALGEAMAVLRETYGDGGHPRDLVREAHMRQQLRAATREFGDEVAVVCGAWHVPALAAKFTVAADRALLKGLPKVKAELTWVPWTHRRLARRSGYGAGIDSPGWYGHLFSARDRPVERWMTKVAGLLREEDYAISPAHVIEAVRLATTLAALRGRPLPGLAETTDAVRAVLCEGSDVPLGLIQERLIVGDVLGEVPDAAPAVPLQRDLARAQRGLRLKPEAPERELELDLRKETDAGRSRLLHRLRLLGIDWGEPVRARSTGTFRESWRLRWEPELSVRVAEAGVWGTTVLGAATAKAESVAAETTALVEITSLAERCLLAELPDALPVVMRALADRAALDTDVAHLAQALPALARTLRYGDVRGTTTAGLAEVAAGLAERICVGLPPACAGLDADGAAEMRTHLDAVHTATALLVDPAGAGAGGLRERWSSVLSRLAARDTVPGVLRGRAVRLLLDDGRIESEDAARHMGLALSPGTAPADAAAWIEGFVGGASGGGMLLVHDERLRGLVDGWLTSVTPEAFTDVLPLLRRTFAAYEAGVRRTLGELVRRGPAGRPGPGDAAAPGFGAGLDAARADAVLPLVALLLGRAGPGGLHGPDELDELDELDRPDDPNGPDALARRNDPARRDVPAGPDDLDDTNSLVEVGS
>CP032698.1|AYG80970.1|3479100_3480255_-|hypothetical-protein
MTSTRPSTDERLRRWRLVLGGEPGAEGTGRALTGQDAAMDGALAALYVRGKGTAKDRGAGLGASAPSVARWLGDIRGYFPSSVVQIMQRDAIERLGLATLLLEPEMLEAVEADVHLVGTLLSLNKAMPETTRETARAVVRKVVADLEKRLATRTRATLTGALDRSTRISRPRHRDIDWDRTIRANLKNYLPEHGTVVPERLIGHGRAARGVKKDVVLCIDQSGSMAASVVYASVFGAVLASMRSIATRLVVFDTAVVDLTDQLDDPVDVLFGTQLGGGTDINRALAYCQSQITRPADTVVVLISDLYEGGIRDEMLKRVAAMKASGVQFVALLALSDEGAPAYDREHAAALAALGAPAFACTPDLFPEVMAAAIERRPLPIPQA
>CP032698.1|AYG80969.1|3477691_3478870_-|Succinate--CoA-ligase-[ADP-forming]-subunit-beta
MDLFEYQARDLFAKHGVPVLAGEVIDTPEAAREATERLGGKSVVKAQVKVGGRGKAGGVKLAANADEAVARATDILGMDIKGHTVHKVMIAELSPEIEAEYYVSYLLDRTNRTFLAMASVQGGMDIEEVAEKTPEALAKVPVNAVEGVDIEKAREIVALAKFPADVAEGVAEAMVTLWKTFVAEDALLVEVNPLVKTKDGRILALDGKVSLDENAEFRQPEHEALEDKAAANPLEAAAKAKNLNYVKLDGEVGIIGNGAGLVMSTLDVVAYAGENHGGVKPANFLDIGGGASAQVMANGLEIILGDEDVKSVFVNVFGGITACDEVANGIIQALALLADKGEEVTKPLVVRLDGNNAELGRKILSDANHPLVQRVDTMDGAADKAAELAAAK
>CP032698.1|AYG80968.1|3476784_3477669_-|Succinate--CoA-ligase-[ADP-forming]-subunit-alpha
MAIFLTKDSKVIVQGMTGATGMKHTKLMLADGTNIVGGVNPRKAGTSVDFDGTDVPVFGSVKEAMEKTGADVSVLFVPPAHAKAAVVEAIDAEIGLAVVITEGIAVHDSAAFWAYANSKGNKTRIIGPNCPGLITPGQSNAGIIPGDITKPGRIGLVSKSGTLTYQMMYELRDIGFSSAVGIGGDPVIGTTHIDALAAFEADPETDLIVMIGEIGGDAEERAADYIKANVTKPVVGYVAGFTAPEGKTMGHAGAIVSGSSGTAQAKKEALEAAGVKVGKTPTETAKLARAILGS
>CP032698.1|AYG80967.1|3475211_3476684_+|hypothetical-protein
MTQSTADTKATDAMSPLPTPKERRRLREAKDLSEAQVAATVGVTRATVRSWETGRTTPRGRKGQIYARFLASIASELAAAANPDGTAPPSSRPAGSTATPPATPGTPTTPATPRDPSTPGPSPTPSTADGTAKGDSGSEHVGAGAEASCAVAADPAPGGDATTPPDTPQGDELAPTEPHAPRTDTPRGDEAAATEPHAPPPRTPRAGEAEDAEPDALTPAQAFDALYLAAAPALAQQTYLLTGRTRLARESVERAFHLAWEHWPQVATDRDPVGWVRAAAHEYALSPWHRFRRTHKHPDQPPVEPERRALLDTLLDLPPAYRRTALLYDGLGLDLPDAAAEMEASTPAAASRVLNARAALVDRVPAARRAKTPEALSSVLRERITDLALAGPPALTRLPSARVVRTGGERRRRFWTRSAIAFTTLIVSATSFTVVTVPHHHVRPVPLGVRVGGVPVNSGPQRLTSEDLELRDKLRTEPARGPHRLVLDIR
>CP032698.1|AYG80966.1|3473154_3475038_-|hypothetical-protein
MTQVTERSLLLPTARARSSVLATCLLRGAIAAGLGLGVLAVVVIVLWISSPYPDSGPGGALRTAASLWLLAHGTPLVRPETLTGAPAPVGLVPLLLVALPAWLAHRAARDALMPDDEAYDEVDAGPLPSGPAVFGAVTCGYLAVAAAVVLYADAGPLPADLLGAALHVPLTVALATAAGVWTAHGRPVGPLPDVVPARVRAALLGAPAHAAVRAAGAATAVLLGGGALLAGAGLAWHIGVAEDAFLRLAEDWSGRFAVLLLAVALVPNAAVWGASYGLGPGFAVGTGATAGPLGAAGTATLPHFPLLAAVPPAGHGSWWTWAAGGVPLLAGLVLARFTARAAVSEGWGRRATARAALLGAALCGCALAVLAAVAGGPLGTGSLAALGPVWWRTGGAALGWAAAVGMPGALVLRAWRMRRAAPRRPVRARLAAALAWRPARRNRGVAAPVVERGPADDGAYDFLPLGETGLWHEEGAREARWAALKEASGGLMADIPPTGSAPLAPPVPGPVPGRPESMPGAGAGPGESADPAVRADPATPAGPGAPEAASGPGWEVAPGPGPQAHLSQPQGSPPRPTHEPAFDPAAQPDEEPPAAPTTEPGTGPGPDAHAARPGPDAPAPGARPGAD
>CP032698.1|AYG80965.1|3472320_3473136_+|hypothetical-protein
MQDRPHQLFAARQSSTPGSPHSTDPGNAGPEGTGSGTGAGSADDNPFAPPPEGRPDQPWQPRRPAAGEDEGQSGQGGQGGPNQGSPWGSQWSDRQPGRAPGVFGRRPERPEDRPGQNPPPPGGGLRWDPTDPAQRRARYALLSGMWAFFFALFDMPEIALLLGALGLYWAISSLRAKPKPPSAPSATSPAPAPAAQQAPQPSSAGKPQVTAAVTGLVTAVLALTVVASSFTMQLVYRDYYTCVDDALTKTGQLACNDLIPEKLVPLFGVKE
>CP032698.1|AYG80975.1|3487287_3487701_-|Pivalyl-CoA-mutase-small-subunit
MGVTGPIRVVVAKPGLDGHDRGAKVIARALRDAGMEVIYTGLHQTPEQIVDTAIQEDADAIGLSILSGAHNTLFAKVLELLRERDAEDIKVFGGGIIPEADIPPLKELGVAEIFTPGATTASIVTWVNANVRQTAGA
>CP032698.1|AYG80976.1|3488105_3488927_+|Extracellular-esterase-EstB
MQLFTLLPPCLRRAWLSAALVRATALDLAVLAGHLLLYPSGLTPERRPASDAAAPQLPTAGRAHPPVVLLHGFIDNRSVFVLLRRSLARHGWRHLESLNYSPLTVDVRVAAELLGRHVEEVCARTGHHEVDIVGHSLGGLIARYYVQRLGGDVRVRTLVTLATPHTGTRSARLAHAHPIVRQMCPGSDLVEELRGPAPGIRTRFVSFWSDLDTVMIPVETARIDHPDLVARNVRVTGIGHLAMPVHPAVAAGVRQALTAGEAEATEQDAFSVA
>CP032698.1|AYG80977.1|3489199_3490915_+|Glycyl-glycine-endopeptidase-LytM
MGTPAAGSVAEAREKLVTDQHAHAGYVGHDGYLNGSSGHDGTGPHTQSTGSFAVDPLFGAMQGAHADQNAHPAGGTGQFDTGTFAAPYEGTGQWTVPAQATAYEPNGATGTLDGGAPRTGTFDTGRLDENPFSTGQFDTHTFSAGQFATHAFPSQASDTGTFATHAFAAHGGDTGVFPTAPFATPSTHDTGSFDTGSFDTTGQWDASAWHQAQDTGRYDTTAFASAPDSTGQWSLLGTHSETGTYDATAWNSAAPETTATATAALPLLDLHPSEPEPQLPYETAEFAQVELSEETGPTSGPATDDAPVDLPGAAVPGARAEARRGASRRRRTPAKRSALLTVAVPSVCVMGVAGVAVASVSGLSGGKDEGSTVAAASDPASVKPVAANKNLDTQLANLSADASSFADRASRTQERIDLKARQDADRKKKADAAAAKEAARPKFLLPVTQKGLSAYYGQAGVNWMSVHTGIDFPVSYGTPVMSAIDGTVRTQWNSAYGNMAIVTGADGTETWYCHLSSTKIRSGPVKAGDVIAYSGNSGNSTGPHLHFEVRPGGGSSIDPLPWLRSHGLDPT
>CP032698.1|AYG80978.1|3490991_3493487_-|ATP-dependent-DNA-helicase-UvrD1
MSSLFDDSFLADLQPSEEEHPPPPEEPHAPEAVPDDLFGGRFDAPVDRDAHYRGGAPRPAIDAAALLEGLNEQQRAAVVHAGSPLLIVAGAGSGKTRVLTHRIAHLLATRGVHPGQILAITFTNKAAGEMKERVEQLVGPRANAMWVMTFHSACVRILRRESKKLGFTSSFSIYDAADSKRLMALVCRDLELDPKKFPPKAFSAKVSNLKNELIDEETFAGQAAGGTSQAFGSGGGFEKTLAQAYTMYQARLREANALDFDDIIMTTVHLLQAFPDVAEHYRLRFRHVLVDEYQDTNHAQYTLVRELVGPSGEAQAPAELCVVGDADQSIYAFRGATIRNILQFEEDYPNATTILLEQNYRSTQTILSAANAVIERNASRRPKNLWTDAGPGAQITGYVADTEHDEAQFIADEIDRLTDRGDAKAGDVAVFYRTNAQSRVFEEIFIRVGLPYKVVGGVRFYERKEVRDVLAYLRVLSNGEDTVPLRRILNVPKRGIGERAEAMIDALSLREKITFPQALRRVDEAYGMAARSANAVKRFNALMEELRTIVDSGAGPAVVLEAVLERTGYLAELQASTDPQDETRIENLQELAAVALEFEQERSEADGVEGAGTLAEFLEKVALVADSDQIPDEEEDGSGVITLMTLHTAKGLEFPVVFLTGMEDGVFPHMRALGQPKELEEERRLAYVGITRARERLYLTRSSMRSAWGQPSYNPASRFLEEIPVKHLEWKRTGPMAAPAGPVSGKSLGGGIGNSLSSSRSKAGASGFATRRGNEKPVVSLVVGDRVTHDQFGLGTVMSVTGSGSEAQATIDFGDERPKKLLLRYAPVEKL
>CP032698.1|AYG80979.1|3493688_3494846_+|putative-endopeptidase
MPSHRKPRTRMTSSGPAVGVTTAALASVGLFAQGADAAPVVPGQRPSIEEVQKKVDDLYRQADLATQKYDEAKEATATQRATVDGLLDQVAAGTAKLNETRRIIGGYAAAQYRDGGVSPTMTLLFSHDPQAFFDQRRLMGRLSDEQQRTLTTFEAERAAGAKKRAEASRGLAALTTSQQTLRAGKQEVQAKLTAARTLLSTLTAQEKARLAALEQKKQDDAKRRAAELAARQEAAARQAAAAHPKPAPPAGHAPSAPSTPPAPSTPPAPTSKAAEALAFARAQLGKPYVWGATGPASYDCSGLTQAAWKAAGVDLPRTTWDQVKTGSRVATADLEPGDLVFFYDDISHVGMYIGNGMMIHAPHSGAYVREESIYYMPIYGSVRPG
>CP032698.1|AYG80980.1|3494861_3495215_-|hypothetical-protein
MDVLINVFVGLHIIGIASLLGGFLTQMKAMSAGTARFVPAMLHGALTMLVTGVALVGLNQADDMSVNTLKIGVKLAVLIVILGLVYVKRDDEKIHKGVFGAVGGLTVVNIFIALLWH
>CP032698.1|AYG80981.1|3495564_3496644_+|putative-endopeptidase
MKALVAAHRKPKQHPLGGPAARTAATLALASAATATLFEGSGHAEPKLTPAQVKAKVDQLYHDAEVATEAYDGTKEKADATERSLGELRDEAARRTERLNSARNALGSLAAAQYRSGGVAPELQLILSSDPKRYLDDAAFAERAGDRTATTVAGVRKQLAELDRLHARAEGKLAQLRGQQSTLRRQKSDIQSKITAAEALLAQLTAADRVSYEKAETAGAAPADSPRVTRSAEAPRTPPVAVPGSRAAAAVAFAYSALGKPYVWGATGPSSFDCSGLTQAAWRSAGVQLPRTTYTQINVGSRVARSQLAPGDLVFFYSGISHVGLYIGGGQMIHAPHPGAPVRIAPIDQMPFAGAARPA
>CP032698.1|AYG80982.1|3496739_3497876_-|hypothetical-protein
MSLTGTPLLVIAILAAAAALLLPLVLWTRIGGPAFVRGLSRLLMLGFAQVTAILVVFLLVNNANGLYDTWGDLLGGGDHVNAAPDLGPDGTGGRNAASEPKVKQQFEPYTNKVGKGVVKTVLKGQVSGVEGDVAVWLPPQYDDPEYRDKTFPVVELLPGYPGSIGAWFGTLKAQEQLTPMMERGEVAPFILVSPRTTLLGGKDTGCANVPGVVNADTWLSVDVRKMVTDNFRAATGADGWAVAGYSAGAHCAAKLAIEHPDRYRAGVDLSGYNDPAAEKDSITAKDPKLRQESNPLWILKHAKTPPHISLYVSGERTDGYNDGLALKAAAKPPTAVTVVKLNGGGHASAVWKSQVPEVFRWLTREMGAGAKAADKQGV
>CP032698.1|AYG80983.1|3498006_3498687_-|Oxygen-regulatory-protein-NreC
MTEETTDRHVRVVLVDDHRMFRTGVQAEIGRTETTGVEVVGEAADVDQAITVITATRPEVVLLDVHLPGGGGVEVLRRSAAMMGDAENPVRFLALSVSDAAEDVIGVIRGGARGYVTKTITGTDLVDSIFRVQDGDAVFSPRLAGFVLDAFASTDAPPVDEDMDRLTQREREVLRLIARGYAYKEIAKQLFISVKTVESHVSAVLRKLQLSNRHELTRWATARRLV
>CP032698.1|AYG80984.1|3498683_3499991_-|hypothetical-protein
MPGVGRTCDDRCMPVVSPRLSSPEADEAPVRKLYRSAEGRLLGGVARGLAGHLGLPVVWVRVVFLGLLSINGLGALLYAVFWFFVPLGLGGTTGQRSAFELSPDGRRRLRKPDKGQVVALIALLFGAAIFASKVDVGGWANPYIFPSVLIGVGVVLVWRQADNTRRARWTEGARRSRWLPVARGLAGVALVGTGLTGFVVVNGSAAQLGNVLTAAIAVLAGIALLAGPYLVRMTQDLSEERLMRIRAQERAEVAAHVHDSVLHTLTLIQRNAESAGEVRRLARAQERELRAWLYKPEGTGREEEPETLAEAVKKAAAEVEDKHGVPLEVVVVGDCPLDDGLSAQMQAAREAMVNAAKYGGEGGAVQVYAEVEGRTVFVSVRDRGPGFDPDAVPADRMGVRESIIGRMQRNGGTARLRSVPGGGTEVELEMERAQG

Crispr_ID: CP032698_22

• CRISPR_ID: CP032698_22
• CRISPR_location: 3570021-3570121
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_22

Consensus_repeat	Method
CCCCTGGGGCTCCGCCCCAGACCCCG	CRISPRCasFinder

spacers of CP032698_22

>22.1|3570047|49|CP032698|CRISPRCasFinder
AGGCGCCTTGCCCACCCACCCGCCCGTGCAGCGGGTTGAACCAGCTGAG

CRISPR arrays and Neighbor proteins around CP032698_22

CRISPR arrays

The CRISPR arrays of CP032698_22

>merge|CP032698|22|3570021-3570121|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCGAGGCGCCTTGCCCACCCACCCGCCCGTGCAGCGGGTTGAACCAGCTGAGCCCCTGGGGCTCCGCCCCAGACCCCG

>CP032698|22|18|3570021-3570121|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCG	AGGCGCCTTGCCCACCCACCCGCCCGTGCAGCGGGTTGAACCAGCTGAG
CCCCTGGGGCTCCGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81043.1|3570893_3572741_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	unknown	unknown	gnl|CDD|234729
CP032698.1|AYG81040.1|3566642_3567596_-|hypothetical-protein	unknown	unknown	gnl|CDD|341130
CP032698.1|AYG81032.1|3560026_3561166_-|tRNA-N6-adenosine-threonylcarbamoyltransferase	unknown	unknown	gnl|CDD|236585
CP032698.1|AYG81051.1|3580111_3580984_-|tRNA-pseudouridine-synthase-A	unknown	unknown	gnl|CDD|234577
CP032698.1|AYG81046.1|3574875_3576234_-|Phosphoglucosamine-mutase	unknown	unknown	gnl|CDD|237672
CP032698.1|AYG81041.1|3568557_3569988_-|Bifunctional-NAD(P)H-hydrate-repair-enzyme-Nnr	unknown	unknown	gnl|CDD|238576
CP032698.1|AYG81044.1|3572877_3573867_+|Pantothenate-kinase	unknown	unknown	gnl|CDD|235466
CP032698.1|AYG81039.1|3565374_3566529_-|Alanine-racemase	unknown	unknown	gnl|CDD|143481
CP032698.1|AYG81036.1|3563184_3563361_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81045.1|3573943_3574879_+|hypothetical-protein	unknown	unknown	gnl|CDD|129372
CP032698.1|AYG81049.1|3577619_3579242_-|putative-ABC-transporter-ATP-binding-protein-YbiT	unknown	unknown	gnl|CDD|223562
CP032698.1|AYG81037.1|3563524_3564034_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaE	unknown	unknown	gnl|CDD|376771
CP032698.1|AYG81050.1|3579298_3580141_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81047.1|3576338_3576857_-|30S-ribosomal-protein-S9	unknown	unknown	gnl|CDD|178888
CP032698.1|AYG81038.1|3564002_3565238_-|2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,-4-dienoic-acid-hydrolase	unknown	unknown	gnl|CDD|366166
CP032698.1|AYG81042.1|3570521_3570890_-|Holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl|CDD|234610
CP032698.1|AYG81048.1|3576901_3577345_-|50S-ribosomal-protein-L13	unknown	unknown	gnl|CDD|181703
CP032698.1|AYG81034.1|3561788_3562442_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaB	unknown	unknown	gnl|CDD|274750
CP032698.1|AYG81033.1|3561165_3561792_-|N-alpha-acetyltransferase-RimI	unknown	unknown	gnl|CDD|273701
CP032698.1|AYG81035.1|3562521_3563136_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81043.1|3570893_3572741_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP032698.1|AYG81040.1|3566642_3567596_-|hypothetical-protein	gnl|CDD|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	1.20121e-16
CP032698.1|AYG81032.1|3560026_3561166_-|tRNA-N6-adenosine-threonylcarbamoyltransferase	gnl|CDD|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	0
CP032698.1|AYG81051.1|3580111_3580984_-|tRNA-pseudouridine-synthase-A	gnl|CDD|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	9.27044e-107
CP032698.1|AYG81046.1|3574875_3576234_-|Phosphoglucosamine-mutase	gnl|CDD|237672	PRK14318, glmM, phosphoglucosamine mutase; Provisional.	0
CP032698.1|AYG81041.1|3568557_3569988_-|Bifunctional-NAD(P)H-hydrate-repair-enzyme-Nnr	gnl|CDD|238576	cd01171, YXKO-related, B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily.	4.51152e-65
CP032698.1|AYG81039.1|3565374_3566529_-|Alanine-racemase	gnl|CDD|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	6.18972e-161
CP032698.1|AYG81045.1|3573943_3574879_+|hypothetical-protein	gnl|CDD|129372	TIGR00271, Uncharacterized_protein_MJ0678, uncharacterized hydrophobic domain. This domain is in a family of archaeal proteins that includes AF0785 of Archaeoglobus fulgidus and in several eubacterial proteins, including the much longer protein sll1151 from Synechocystis PCC6803.	3.72563e-45
CP032698.1|AYG81049.1|3577619_3579242_-|putative-ABC-transporter-ATP-binding-protein-YbiT	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	2.44536e-96
CP032698.1|AYG81037.1|3563524_3564034_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaE	gnl|CDD|376771	pfam02367, TsaE, Threonylcarbamoyl adenosine biosynthesis protein TsaE. This family of proteins is involved in the synthesis of threonylcarbamoyl adenosine (t(6)A).	5.9496e-47
CP032698.1|AYG81047.1|3576338_3576857_-|30S-ribosomal-protein-S9	gnl|CDD|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	1.19232e-73
CP032698.1|AYG81038.1|3564002_3565238_-|2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,-4-dienoic-acid-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	4.17243e-26
CP032698.1|AYG81042.1|3570521_3570890_-|Holo-[acyl-carrier-protein]-synthase	gnl|CDD|234610	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional.	9.90601e-48
CP032698.1|AYG81048.1|3576901_3577345_-|50S-ribosomal-protein-L13	gnl|CDD|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.83944e-98
CP032698.1|AYG81034.1|3561788_3562442_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaB	gnl|CDD|274750	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ. This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. [Protein synthesis, tRNA and rRNA base modification].	7.99524e-62
CP032698.1|AYG81033.1|3561165_3561792_-|N-alpha-acetyltransferase-RimI	gnl|CDD|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	4.66891e-21
CP032698.1|AYG81044.1|3572877_3573867_+|Pantothenate-kinase	gnl|CDD|235466	PRK05439, PRK05439, pantothenate kinase; Provisional.	0

Protein sequences

>CP032698.1|AYG81041.1|3568557_3569988_-|Bifunctional-NAD(P)H-hydrate-repair-enzyme-Nnr
MRTAYDVDTVRAAERELMTHLPPGTLMQRAAAALAAACANMLGRVYGTRIVLLVGSGDNGGDALYAGARLARRGAGVSAVLLSPDRAHPEGLAALERAGGRVADDPFEVLAAADLVLDGIIGIGGGGGLRPDAVPLARAARGSNALVVAVDLPSGVDADTGEVRGEALRADATVTFGAYKPGLLIDPAREYAGVVHIVPIGLDLPSVPAVEALQHADMADLLPTPAAESDKYRRGVVGVVAGSARYPGAAVLAVAGALRGGAGAVRYVGPGGDAVIARFPETLVSDGSPARAGRVQAWVVGPGLGDGPGVEEVLASDVPVLVDADGLHGLDPEVVRARSAATLLTPHAGEAAALLGVAREEVEAGRLAAARALASRYAATVLLKGSTTLVADAEGPVRVNPTGTPWLATAGSGDVLSGLTGSLLATGLPARDAGAMGAYLHGLAGRHAAQGAPVTAYGVAEALPTAWQDAARPNPQ
>CP032698.1|AYG81040.1|3566642_3567596_-|hypothetical-protein
MPPKRSRRQSWTTYGLVLAAALALAAAPPAAAELPPPPPAHPAAPAPAPAPAAPGDPAPADVLVPGLAPDAHAGPLDTPDQVLPPLVYEPGAAEDAVEPADAPEGAYRLVEYVPQGELAAKPGSCTTRTGPYQRQIERWLRRAVDGRQSAADCAAIRTFQQAQGISPAIGFAGPVTWSRMQFLSARKNPNAAHKCPVKAQRVACVDLTRQLMWVQTGKKVTFGPVPIRSGRASMPTRGGWHKVYWRHKNHWSTIYHQSMPYAQFFDGGQAFHAIYHSVYTSVGSQGCVNLGLADARKLWDVLRKGDGVYVWGHRDGT
>CP032698.1|AYG81039.1|3565374_3566529_-|Alanine-racemase
MTAMTQNPAVRARAEIDLGALRANVRTLRARSSGAQLMAVVKADAYGHGAVPCARAARQAGAAWIGTATPDEALALRAAGIEGPMMCWLWTPGGPWREAIEADIDVSVSGMWALREVTEAARAAGRTARIQLKADTGLGRNGCQPADWPELVHAALAAPEVTVTGLWSHLACADEPGHPSIAAQLSVFEEMLGFAEKAGVTPEVRHIANSPATLTLPESHYDLVRTGIAMYGISPAPELGTARELGLRPVMTLSASVALSKQVPAGHGVSYGHHYVTEHETTLGLVPLGYADGIPRHASGRGPVLVGGKVRTAAGRIAMDQFVVDLEGDTVEPGARAVLFGPGDAGEPTAEDWARAADTIAYEIVTRIGARVPRVHVNERSGAA
>CP032698.1|AYG81038.1|3564002_3565238_-|2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,-4-dienoic-acid-hydrolase
MSETGTGDAVVSAVQDAQAAVGTWRLASIAGAAIGVVAAGAAAGVAIERLTVGRGMRRKARLALDASGPYGALRGTPGKAVADDGTVLYYESDEVEPEAGANGPRKRRLFGRKVPAPVTVVFSHGYCLNQDSWHFQRAALRGVLRTVHWDQRSHGRSDRGKSQRDGVPVDIDRLGRDLKTVIDAAAPTGPLVLVGHSMGGMTIMALADQYPELIRDRVVGVAFVGTSSGKLGEVNYGLPVAGVNAVRRVLPGVLKALGSQAELVERGRRATADLFAGMIKRYSFSSKDVDPAIARFAERMIESTPIDVVAEFYPAFSDHDKTTALAIFAEVPVLVLAGDRDLVTPSSHSEAIADLLPDAELVIVPDGGHLVMLEHPETVTDRLADLLARVGAVPQAANVGTYGSTAQQPGR
>CP032698.1|AYG81037.1|3563524_3564034_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaE
MEAPHSSPAADAGTRLTLNSPSEMQELGRRIAKLLRPGDLVMLTGELGAGKTTLTRGLGEGLGVRGAVTSPTFVIARVHPSLVGGPALVHVDAYRLGGGLDEMEDLDLDVSLPESVVVVEWGEGKVEELSDDRLQVLIDRVVGETDDDRRTVTVTGIGPRWSGAGVEGL
>CP032698.1|AYG81036.1|3563184_3563361_-|hypothetical-protein
MTVPEREAKPQAPRGVPVPLGVSIHDLLASCAAATAVSTPPRESAPTADEGDARKDAA
>CP032698.1|AYG81035.1|3562521_3563136_+|hypothetical-protein
MTVDLHVRTKGEAQVARSSTGFVAGLTAAALAVVGFLAYQASASAPPAADLAAPGAVAAPSSKPSNLPPAGSPADKPDLTVPANSGTGVRVVYALGAKRVWLVGVAKTPKTFAVVPSSISPKPGTYTVLSRTGGKITGSDGVAVDHVVRFASNENVAIGFSSAVDGSMTSPKTAKKTGGIRMSRADGDAMWAFATRNSKVVVVP
>CP032698.1|AYG81034.1|3561788_3562442_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaB
MLLLAVDTATPAVTVALHDGTSVVAESRQVDARRHGELLLPAVDRVLAEAGLNLSAVTDLVVGVGPGPYTGLRVGLVTAATFGSVLGVPVHGLCTLDGLAYASGIEGPFVVATDARRKEVYWARYDDFRTRVGEPSVDRPADIADELSGLPVVGQGAVLYPDSFPLARDPEHQSAGALAALAAEKLAAGAEFLPPTPLYLRRPDAQVPKNYKVVTPK
>CP032698.1|AYG81033.1|3561165_3561792_-|N-alpha-acetyltransferase-RimI
MTGAEATGAGTAGAEAVGAETTGAETTGAETAGAETAGTPATGVVLREMRWWDIAPVLDLEHELFPEDAWSAGMFWSELAHARGPGATRRYVVAESFENGRARLVGYAGLAAAGELADVQTIAAARDQWGTGLGARLLTDLLKHATAFECDEVLLEVRVDNTRAQKLYERFGFEPIGFRRGYYQPGNVDALVMRLTVQEYVQGTEETD
>CP032698.1|AYG81032.1|3560026_3561166_-|tRNA-N6-adenosine-threonylcarbamoyltransferase
MADEPLVLGIETSCDETGVGIVRGTTLLADAVASSVDTHARFGGVVPEIASRAHLEAMVPTIERALKTAGISARDLDGIAVTAGPGLAGALLVGVSAAKAYAYALDKPLYGVNHLASHICVDQLEHGPLPEPTMALLVSGGHSSLLLAPDITADVRPMGATIDDAAGEAFDKIARVLQLGFPGGPVIDRLAKEGDPNAIAFPRGLTGSRDPAYDFSFSGLKTAVARWIEAKRTAGEEVPVRDVAASFQEAVVDVLTRKAVRACKDEGVDHLMIGGGVAANSRLRALAQERCERAGIRLRVPRPGLCTDNGAMVAALGAEMVARNRPASDLELSADSSLPVTEPHVPGEASGHAQGHGHGHAHGHDHDHVHEVSKKNLYS
>CP032698.1|AYG81042.1|3570521_3570890_-|Holo-[acyl-carrier-protein]-synthase
MIIGVGIDVAEIERFGQSIERTPAMLQRLFVESELILPGGERRGVASLAVRFAAKEALAKALGAPAGLLWTDAEVYVEANGQPRLRVRGSVAARAAELGVRHWHVSLSHDAGVASAVVIAEG
>CP032698.1|AYG81043.1|3570893_3572741_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]
MCGIVGYVGGQSALDVVVAGLKRLEYRGYDSAGVAVLADGGLAAAKKAGKLVNLEKALVEAPLPAGATGIGHTRWATHGGPTDTNAHPHLDNAGRVAVVHNGIIENFAALRAELAERGHALASETDTEVVAHLLAECYSSSEDLAEAMRQVCRRLEGAFTLVAVHADEPDVVVGARRNSPLVVGVGEGEAFLASDVAAFIAHTRSALELGQDQVVEVRRDAVVVTDFDGAPAETRAYHVDWDASAAEKGGYDYFMLKEIAEQPKAVADTLLGRIDAAGSLTLDELRIPHAVLREIDKVVVVACGTAYHAGMIAKLAIEHWTRIPCETELASEFRYRDPILDQRTLVIAISQSGETMDTLMALRHAREQGAKVLAICNTNGSTIPRESDAVLYTHAGPEVAVASTKAFLTQLVACYLVALYLGQVRGTKWGDEIGDVVRDLAEIATEVDRVLETMEPVRELARSLAAKNTVLFLGRHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEDLPVVVVVPSPRGRSVLHDKIVSNIQEIRARGARTIVIAEEGDEAVVPYADHLIRIPATPTLLQPLVAAVPLQVFACELATARGNEVDQPRNLAKSVTVE
>CP032698.1|AYG81044.1|3572877_3573867_+|Pantothenate-kinase
MITSPPRSAHRKPEATPYVDLTRAEWSALRDKTPLPLTADEVERLRGLGDVIDLDEVRDIYLPLSRLLNLYVGATANLRGTLNTFLGDAGNGHGTQHGTPFVIGVAGSVAVGKSTVARLLQALLARWPEHPRVELVTTDGFLYPMAELERRGLMSRKGFPESYDRRALTRFVADIKAGKDEVTAPVYSHLIYDIVPDERLVVRRPDILIVEGLNVLQPALPGQDGRTRVGLADYFDFSVYVDARTEDIETWYLNRFRKLRDTAFQNPFSYFRKYTQVSEEEALDYARTTWRTINRPNLVENVAPTRGRATLVVRKGPDHKIQKISLRKL
>CP032698.1|AYG81045.1|3573943_3574879_+|hypothetical-protein
MLHLRLIVPADRTEEVVRTIESTVGTAHLAVLSGAARNPVGDLVLCDVAREAGDELIAELRAIGLDRDGSIAVDHIDLSISKRADKAEAEAPGEGADAVLWESLTDATHEESTLSITYVAFLAVATMLAACGVMLDNAILIVGAMAVGPEFGPLAGISTALVRRAPRLVGRSLLALVVGFASAMLLTAGFGWLMEVLGLFDKSMIEAPRPNTAFIFRPDWMSFVVAFLAGIAGTLSLTSAKSGALIGVAISVTTVPAAANAAMAFSYQDYGQTWGSSWQLLANLAGIVLSGTLTLLAQKALWASQRKRQLP
>CP032698.1|AYG81046.1|3574875_3576234_-|Phosphoglucosamine-mutase
MGRLFGTDGVRGVANSDLTAELALGLSVAAAHVLAEAGTFEGHRPTAVVGRDPRASGEFLEAAVVAGLASAGVDVLRVGVLPTPAVAYLTGVLGADLGVMLSASHNAMPDNGVKFFARGGHKLADELEDRIESIYEQHRTGAPWERPTGAGVGRVRSYKEGFDRYVAHLIGVLPNRLDGLKVVLDEAHGAAARVSPEAFARAGAEVVTIGAEPDGLNINDGCGSTHLDLLKAAVVEHGADLGIAHDGDADRCLAVDAEGNEVDGDQILAVLALAMREAGTLRGNTVVGTVMSNLGFKIAMEGEGIQLVQTGVGDRYVLESMKEHGYALGGEQSGHVIILDHATTGDGTLTGLMLAARVAATRRTLADLAGVMTRLPQVLVNVPDVDKSRVATSAELGTAVAEAERELGATGRVLLRPSGTEPLVRVMVEAADIEQARSVAGRLADVVKSALG
>CP032698.1|AYG81047.1|3576338_3576857_-|30S-ribosomal-protein-S9
MAETTVETPVEGEETYAEVTTFESEVPVEGEYTTESMASRFGDPQPAAGLGRRKNAIARVRIVPGTGKWKINGRTLEDYFPNKVHQQEVNEPFKVLELDNRYDVIARISGGGVSGQAGALRLGVARALNEADVDNNRAALKKAGFLSRDDRAVERKKAGLKKARKAPQYSKR
>CP032698.1|AYG81048.1|3576901_3577345_-|50S-ribosomal-protein-L13
MRTYSPKPGDITRQWHVIDARDVVLGRLATTAANLLRGKHKPVYAPHMDMGDFVIIINADKVHLSGNKKTQKMAYRHSGYPGGLRSVRYDDLLANNPEKAVEKAIKGMIPKNTLGRQMISKLKVYSGDQHPHAAQQPVPFEITQVAQ
>CP032698.1|AYG81049.1|3577619_3579242_-|putative-ABC-transporter-ATP-binding-protein-YbiT
MGHLEAAHLEYYLPDGRVLLGDASFRVAEGSVVALVGANGAGKTTLLRMISGELQPHGGSVSVSGGLGVMPQFVGSVRDERTVRDLLVSVAQPRIREAAAEVDAAEHLIMTVDDEAAQMKYAQALSDWAEARGYEAETVWDMCTMAALGMPYDKAQFREVRTLSGGEQKRLVLEALLRGPDEVLLLDEPDNYLDVPGKRWLEERLRETRKTVLFVSHDRELLSRAAERIVSLEPSPAGTDVWVHGAGFATYHQARRERFARFEELKRRWDEEHARLKALVLRLRNQAAISPDMASRYHAMQTRFKKFEEAGPPPEPPREQEITMRLRGGRTGVRALTCENLELTGLMKPFSLEVFYGERVAVLGSNGSGKSHFLRLLAGDASVAYTGNWKLGARVVPGHFAQTHAHPELLGRTLVDILWSEHAKDRGAAMSVLRRYELERQGDQPFEKLSGGQQARFQILLLELAGTTALLLDEPTDNLDLESAEALQDGLESYDGTVLAVTHDRWFSKSFDRYLVFGSDGVVRETSEPVWDERRVERAR
>CP032698.1|AYG81050.1|3579298_3580141_+|hypothetical-protein
MSFGQGGPGWGPGDQQTPDWAALADASAARNRRKKWIFIGAGAVATAAVVAVVAAVIVNAGSSDDGKSTSALPSPPALPSDSAQPGPSFSHVAPPPPPNPYDFVASAKKDTAPLGADTLFPGQSLTLGSGAYAKGPTGKVTDCASVTQGSLGATLANNGCRQVIRATFTKDGVAVTVGVAVFDTDVQATKAKEQASGGIASLSGSGVNTFCRGGSVCRNTTNSYGRYAYFTISGFTNGKNVTQGDTAVFAAGNDLAKFTFDQIVARGRNQASAAAARPAA
>CP032698.1|AYG81051.1|3580111_3580984_-|tRNA-pseudouridine-synthase-A
MSDEVEPGLVRVRLDLSYDGKDFSGWARQPLGRRTVQGEIEDALRTVTRSDVSYDLTVAGRTDAGVHARGQVAHVDLPQEVWAEHREKLLRRMAGRLPHDVRIWRIAEAPSGFNARFSAIWRRYAYRVTDNVGGVDPLLRGHVLWHDWELDVEAMNAASAALLGEHDFAAYCKKREGATTIRTLQELSWARGDDGIVTATVRADAFCHNMVRSLVGALLYVGDGHRGVEWPGKVLAAAVRDSSVHVVKPHGLTLEEVGYPADELLAARSKEARNLRTLPGSSGGGPGGCC

Crispr_ID: CP032698_23

• CRISPR_ID: CP032698_23
• CRISPR_location: 3570253-3570503
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP032698_23

Consensus_repeat	Method
AGGGGCGCGGGGAACTGCGCGA	PILER-CR

spacers of CP032698_23

>23.1|3570275|34|CP032698|PILER-CR
GAAGCGAGCACGGTCCGCACACGACCGAGTGGTT
>23.2|3570331|36|CP032698|PILER-CR
CCAGCCACCCGCGGCCCGCAGACGAACACGGGTTTT
>23.3|3570389|37|CP032698|PILER-CR
CCAGCCCCGTACGGCCCGCAGCCGAAAGCGGGTTTCC
>23.4|3570448|34|CP032698|PILER-CR
GACGCGACCCCGGCCCGCACACGCCCGGGGTTCA

CRISPR arrays and Neighbor proteins around CP032698_23

CRISPR arrays

The CRISPR arrays of CP032698_23

>merge|CP032698|23|3570253-3570503|PILER-CR
AGGGGCGCGGGGAACTGCGCGAGAAGCGAGCACGGTCCGCACACGACCGAGTGGTTAGGGGCGCGGGGAACTGCGCGACCAGCCACCCGCGGCCCGCAGACGAACACGGGTTTTGGGGGCGCGGGGAACTGCGCGACCAGCCCCGTACGGCCCGCAGCCGAAAGCGGGTTTCCAGGGGCGCGAGGAACTGCGCAAGACGCGACCCCGGCCCGCACACGCCCGGGGTTCAAGGGGCGCGAGGAACTGCGCAA

>CP032698|23|6|3570253-3570503|PILER-CR
AGGGGCGCGGGGAACTGCGCGA	GAAGCGAGCACGGTCCGCACACGACCGAGTGGTT
AGGGGCGCGGGGAACTGCGCGA	CCAGCCACCCGCGGCCCGCAGACGAACACGGGTTTT
GGGGGCGCGGGGAACTGCGCGA	CCAGCCCCGTACGGCCCGCAGCCGAAAGCGGGTTTCC
AGGGGCGCGAGGAACTGCGCAA	GACGCGACCCCGGCCCGCACACGCCCGGGGTTCA
AGGGGCGCGAGGAACTGCGCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81043.1|3570893_3572741_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	unknown	unknown	gnl|CDD|234729
CP032698.1|AYG81040.1|3566642_3567596_-|hypothetical-protein	unknown	unknown	gnl|CDD|341130
CP032698.1|AYG81032.1|3560026_3561166_-|tRNA-N6-adenosine-threonylcarbamoyltransferase	unknown	unknown	gnl|CDD|236585
CP032698.1|AYG81051.1|3580111_3580984_-|tRNA-pseudouridine-synthase-A	unknown	unknown	gnl|CDD|234577
CP032698.1|AYG81046.1|3574875_3576234_-|Phosphoglucosamine-mutase	unknown	unknown	gnl|CDD|237672
CP032698.1|AYG81041.1|3568557_3569988_-|Bifunctional-NAD(P)H-hydrate-repair-enzyme-Nnr	unknown	unknown	gnl|CDD|238576
CP032698.1|AYG81044.1|3572877_3573867_+|Pantothenate-kinase	unknown	unknown	gnl|CDD|235466
CP032698.1|AYG81039.1|3565374_3566529_-|Alanine-racemase	unknown	unknown	gnl|CDD|143481
CP032698.1|AYG81036.1|3563184_3563361_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81045.1|3573943_3574879_+|hypothetical-protein	unknown	unknown	gnl|CDD|129372
CP032698.1|AYG81049.1|3577619_3579242_-|putative-ABC-transporter-ATP-binding-protein-YbiT	unknown	unknown	gnl|CDD|223562
CP032698.1|AYG81037.1|3563524_3564034_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaE	unknown	unknown	gnl|CDD|376771
CP032698.1|AYG81050.1|3579298_3580141_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81047.1|3576338_3576857_-|30S-ribosomal-protein-S9	unknown	unknown	gnl|CDD|178888
CP032698.1|AYG81038.1|3564002_3565238_-|2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,-4-dienoic-acid-hydrolase	unknown	unknown	gnl|CDD|366166
CP032698.1|AYG81042.1|3570521_3570890_-|Holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl|CDD|234610
CP032698.1|AYG81048.1|3576901_3577345_-|50S-ribosomal-protein-L13	unknown	unknown	gnl|CDD|181703
CP032698.1|AYG81034.1|3561788_3562442_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaB	unknown	unknown	gnl|CDD|274750
CP032698.1|AYG81033.1|3561165_3561792_-|N-alpha-acetyltransferase-RimI	unknown	unknown	gnl|CDD|273701
CP032698.1|AYG81035.1|3562521_3563136_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81043.1|3570893_3572741_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP032698.1|AYG81040.1|3566642_3567596_-|hypothetical-protein	gnl|CDD|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	1.20121e-16
CP032698.1|AYG81032.1|3560026_3561166_-|tRNA-N6-adenosine-threonylcarbamoyltransferase	gnl|CDD|236585	PRK09604, PRK09604, tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD.	0
CP032698.1|AYG81051.1|3580111_3580984_-|tRNA-pseudouridine-synthase-A	gnl|CDD|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	9.27044e-107
CP032698.1|AYG81046.1|3574875_3576234_-|Phosphoglucosamine-mutase	gnl|CDD|237672	PRK14318, glmM, phosphoglucosamine mutase; Provisional.	0
CP032698.1|AYG81041.1|3568557_3569988_-|Bifunctional-NAD(P)H-hydrate-repair-enzyme-Nnr	gnl|CDD|238576	cd01171, YXKO-related, B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily.	4.51152e-65
CP032698.1|AYG81039.1|3565374_3566529_-|Alanine-racemase	gnl|CDD|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	6.18972e-161
CP032698.1|AYG81045.1|3573943_3574879_+|hypothetical-protein	gnl|CDD|129372	TIGR00271, Uncharacterized_protein_MJ0678, uncharacterized hydrophobic domain. This domain is in a family of archaeal proteins that includes AF0785 of Archaeoglobus fulgidus and in several eubacterial proteins, including the much longer protein sll1151 from Synechocystis PCC6803.	3.72563e-45
CP032698.1|AYG81049.1|3577619_3579242_-|putative-ABC-transporter-ATP-binding-protein-YbiT	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	2.44536e-96
CP032698.1|AYG81037.1|3563524_3564034_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaE	gnl|CDD|376771	pfam02367, TsaE, Threonylcarbamoyl adenosine biosynthesis protein TsaE. This family of proteins is involved in the synthesis of threonylcarbamoyl adenosine (t(6)A).	5.9496e-47
CP032698.1|AYG81047.1|3576338_3576857_-|30S-ribosomal-protein-S9	gnl|CDD|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	1.19232e-73
CP032698.1|AYG81038.1|3564002_3565238_-|2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,-4-dienoic-acid-hydrolase	gnl|CDD|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	4.17243e-26
CP032698.1|AYG81042.1|3570521_3570890_-|Holo-[acyl-carrier-protein]-synthase	gnl|CDD|234610	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional.	9.90601e-48
CP032698.1|AYG81048.1|3576901_3577345_-|50S-ribosomal-protein-L13	gnl|CDD|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.83944e-98
CP032698.1|AYG81034.1|3561788_3562442_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaB	gnl|CDD|274750	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ. This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. [Protein synthesis, tRNA and rRNA base modification].	7.99524e-62
CP032698.1|AYG81033.1|3561165_3561792_-|N-alpha-acetyltransferase-RimI	gnl|CDD|273701	TIGR01575, rimI, ribosomal-protein-alanine acetyltransferase. Members of this model belong to the GCN5-related N-acetyltransferase (GNAT) superfamily. This model covers prokarotes and the archaea. The seed contains a characterized accession for Gram negative E. coli. An untraceable characterized accession (PIR|S66013) for Gram positive B. subtilis scores well (205.0) in the full alignment. Characterized members are lacking in the archaea. Noise cutoff (72.4) was set to exclude M. loti paralog of rimI. Trusted cutoff (80.0) was set at next highest scoring member in the mini-database. [Protein synthesis, Ribosomal proteins: synthesis and modification].	4.66891e-21
CP032698.1|AYG81044.1|3572877_3573867_+|Pantothenate-kinase	gnl|CDD|235466	PRK05439, PRK05439, pantothenate kinase; Provisional.	0

Protein sequences

>CP032698.1|AYG81041.1|3568557_3569988_-|Bifunctional-NAD(P)H-hydrate-repair-enzyme-Nnr
MRTAYDVDTVRAAERELMTHLPPGTLMQRAAAALAAACANMLGRVYGTRIVLLVGSGDNGGDALYAGARLARRGAGVSAVLLSPDRAHPEGLAALERAGGRVADDPFEVLAAADLVLDGIIGIGGGGGLRPDAVPLARAARGSNALVVAVDLPSGVDADTGEVRGEALRADATVTFGAYKPGLLIDPAREYAGVVHIVPIGLDLPSVPAVEALQHADMADLLPTPAAESDKYRRGVVGVVAGSARYPGAAVLAVAGALRGGAGAVRYVGPGGDAVIARFPETLVSDGSPARAGRVQAWVVGPGLGDGPGVEEVLASDVPVLVDADGLHGLDPEVVRARSAATLLTPHAGEAAALLGVAREEVEAGRLAAARALASRYAATVLLKGSTTLVADAEGPVRVNPTGTPWLATAGSGDVLSGLTGSLLATGLPARDAGAMGAYLHGLAGRHAAQGAPVTAYGVAEALPTAWQDAARPNPQ
>CP032698.1|AYG81040.1|3566642_3567596_-|hypothetical-protein
MPPKRSRRQSWTTYGLVLAAALALAAAPPAAAELPPPPPAHPAAPAPAPAPAAPGDPAPADVLVPGLAPDAHAGPLDTPDQVLPPLVYEPGAAEDAVEPADAPEGAYRLVEYVPQGELAAKPGSCTTRTGPYQRQIERWLRRAVDGRQSAADCAAIRTFQQAQGISPAIGFAGPVTWSRMQFLSARKNPNAAHKCPVKAQRVACVDLTRQLMWVQTGKKVTFGPVPIRSGRASMPTRGGWHKVYWRHKNHWSTIYHQSMPYAQFFDGGQAFHAIYHSVYTSVGSQGCVNLGLADARKLWDVLRKGDGVYVWGHRDGT
>CP032698.1|AYG81039.1|3565374_3566529_-|Alanine-racemase
MTAMTQNPAVRARAEIDLGALRANVRTLRARSSGAQLMAVVKADAYGHGAVPCARAARQAGAAWIGTATPDEALALRAAGIEGPMMCWLWTPGGPWREAIEADIDVSVSGMWALREVTEAARAAGRTARIQLKADTGLGRNGCQPADWPELVHAALAAPEVTVTGLWSHLACADEPGHPSIAAQLSVFEEMLGFAEKAGVTPEVRHIANSPATLTLPESHYDLVRTGIAMYGISPAPELGTARELGLRPVMTLSASVALSKQVPAGHGVSYGHHYVTEHETTLGLVPLGYADGIPRHASGRGPVLVGGKVRTAAGRIAMDQFVVDLEGDTVEPGARAVLFGPGDAGEPTAEDWARAADTIAYEIVTRIGARVPRVHVNERSGAA
>CP032698.1|AYG81038.1|3564002_3565238_-|2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,-4-dienoic-acid-hydrolase
MSETGTGDAVVSAVQDAQAAVGTWRLASIAGAAIGVVAAGAAAGVAIERLTVGRGMRRKARLALDASGPYGALRGTPGKAVADDGTVLYYESDEVEPEAGANGPRKRRLFGRKVPAPVTVVFSHGYCLNQDSWHFQRAALRGVLRTVHWDQRSHGRSDRGKSQRDGVPVDIDRLGRDLKTVIDAAAPTGPLVLVGHSMGGMTIMALADQYPELIRDRVVGVAFVGTSSGKLGEVNYGLPVAGVNAVRRVLPGVLKALGSQAELVERGRRATADLFAGMIKRYSFSSKDVDPAIARFAERMIESTPIDVVAEFYPAFSDHDKTTALAIFAEVPVLVLAGDRDLVTPSSHSEAIADLLPDAELVIVPDGGHLVMLEHPETVTDRLADLLARVGAVPQAANVGTYGSTAQQPGR
>CP032698.1|AYG81037.1|3563524_3564034_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaE
MEAPHSSPAADAGTRLTLNSPSEMQELGRRIAKLLRPGDLVMLTGELGAGKTTLTRGLGEGLGVRGAVTSPTFVIARVHPSLVGGPALVHVDAYRLGGGLDEMEDLDLDVSLPESVVVVEWGEGKVEELSDDRLQVLIDRVVGETDDDRRTVTVTGIGPRWSGAGVEGL
>CP032698.1|AYG81036.1|3563184_3563361_-|hypothetical-protein
MTVPEREAKPQAPRGVPVPLGVSIHDLLASCAAATAVSTPPRESAPTADEGDARKDAA
>CP032698.1|AYG81035.1|3562521_3563136_+|hypothetical-protein
MTVDLHVRTKGEAQVARSSTGFVAGLTAAALAVVGFLAYQASASAPPAADLAAPGAVAAPSSKPSNLPPAGSPADKPDLTVPANSGTGVRVVYALGAKRVWLVGVAKTPKTFAVVPSSISPKPGTYTVLSRTGGKITGSDGVAVDHVVRFASNENVAIGFSSAVDGSMTSPKTAKKTGGIRMSRADGDAMWAFATRNSKVVVVP
>CP032698.1|AYG81034.1|3561788_3562442_-|tRNA-threonylcarbamoyladenosine-biosynthesis-protein-TsaB
MLLLAVDTATPAVTVALHDGTSVVAESRQVDARRHGELLLPAVDRVLAEAGLNLSAVTDLVVGVGPGPYTGLRVGLVTAATFGSVLGVPVHGLCTLDGLAYASGIEGPFVVATDARRKEVYWARYDDFRTRVGEPSVDRPADIADELSGLPVVGQGAVLYPDSFPLARDPEHQSAGALAALAAEKLAAGAEFLPPTPLYLRRPDAQVPKNYKVVTPK
>CP032698.1|AYG81033.1|3561165_3561792_-|N-alpha-acetyltransferase-RimI
MTGAEATGAGTAGAEAVGAETTGAETTGAETAGAETAGTPATGVVLREMRWWDIAPVLDLEHELFPEDAWSAGMFWSELAHARGPGATRRYVVAESFENGRARLVGYAGLAAAGELADVQTIAAARDQWGTGLGARLLTDLLKHATAFECDEVLLEVRVDNTRAQKLYERFGFEPIGFRRGYYQPGNVDALVMRLTVQEYVQGTEETD
>CP032698.1|AYG81032.1|3560026_3561166_-|tRNA-N6-adenosine-threonylcarbamoyltransferase
MADEPLVLGIETSCDETGVGIVRGTTLLADAVASSVDTHARFGGVVPEIASRAHLEAMVPTIERALKTAGISARDLDGIAVTAGPGLAGALLVGVSAAKAYAYALDKPLYGVNHLASHICVDQLEHGPLPEPTMALLVSGGHSSLLLAPDITADVRPMGATIDDAAGEAFDKIARVLQLGFPGGPVIDRLAKEGDPNAIAFPRGLTGSRDPAYDFSFSGLKTAVARWIEAKRTAGEEVPVRDVAASFQEAVVDVLTRKAVRACKDEGVDHLMIGGGVAANSRLRALAQERCERAGIRLRVPRPGLCTDNGAMVAALGAEMVARNRPASDLELSADSSLPVTEPHVPGEASGHAQGHGHGHAHGHDHDHVHEVSKKNLYS
>CP032698.1|AYG81042.1|3570521_3570890_-|Holo-[acyl-carrier-protein]-synthase
MIIGVGIDVAEIERFGQSIERTPAMLQRLFVESELILPGGERRGVASLAVRFAAKEALAKALGAPAGLLWTDAEVYVEANGQPRLRVRGSVAARAAELGVRHWHVSLSHDAGVASAVVIAEG
>CP032698.1|AYG81043.1|3570893_3572741_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]
MCGIVGYVGGQSALDVVVAGLKRLEYRGYDSAGVAVLADGGLAAAKKAGKLVNLEKALVEAPLPAGATGIGHTRWATHGGPTDTNAHPHLDNAGRVAVVHNGIIENFAALRAELAERGHALASETDTEVVAHLLAECYSSSEDLAEAMRQVCRRLEGAFTLVAVHADEPDVVVGARRNSPLVVGVGEGEAFLASDVAAFIAHTRSALELGQDQVVEVRRDAVVVTDFDGAPAETRAYHVDWDASAAEKGGYDYFMLKEIAEQPKAVADTLLGRIDAAGSLTLDELRIPHAVLREIDKVVVVACGTAYHAGMIAKLAIEHWTRIPCETELASEFRYRDPILDQRTLVIAISQSGETMDTLMALRHAREQGAKVLAICNTNGSTIPRESDAVLYTHAGPEVAVASTKAFLTQLVACYLVALYLGQVRGTKWGDEIGDVVRDLAEIATEVDRVLETMEPVRELARSLAAKNTVLFLGRHVGYPVALEGALKLKELAYMHAEGFAAGELKHGPIALIEEDLPVVVVVPSPRGRSVLHDKIVSNIQEIRARGARTIVIAEEGDEAVVPYADHLIRIPATPTLLQPLVAAVPLQVFACELATARGNEVDQPRNLAKSVTVE
>CP032698.1|AYG81044.1|3572877_3573867_+|Pantothenate-kinase
MITSPPRSAHRKPEATPYVDLTRAEWSALRDKTPLPLTADEVERLRGLGDVIDLDEVRDIYLPLSRLLNLYVGATANLRGTLNTFLGDAGNGHGTQHGTPFVIGVAGSVAVGKSTVARLLQALLARWPEHPRVELVTTDGFLYPMAELERRGLMSRKGFPESYDRRALTRFVADIKAGKDEVTAPVYSHLIYDIVPDERLVVRRPDILIVEGLNVLQPALPGQDGRTRVGLADYFDFSVYVDARTEDIETWYLNRFRKLRDTAFQNPFSYFRKYTQVSEEEALDYARTTWRTINRPNLVENVAPTRGRATLVVRKGPDHKIQKISLRKL
>CP032698.1|AYG81045.1|3573943_3574879_+|hypothetical-protein
MLHLRLIVPADRTEEVVRTIESTVGTAHLAVLSGAARNPVGDLVLCDVAREAGDELIAELRAIGLDRDGSIAVDHIDLSISKRADKAEAEAPGEGADAVLWESLTDATHEESTLSITYVAFLAVATMLAACGVMLDNAILIVGAMAVGPEFGPLAGISTALVRRAPRLVGRSLLALVVGFASAMLLTAGFGWLMEVLGLFDKSMIEAPRPNTAFIFRPDWMSFVVAFLAGIAGTLSLTSAKSGALIGVAISVTTVPAAANAAMAFSYQDYGQTWGSSWQLLANLAGIVLSGTLTLLAQKALWASQRKRQLP
>CP032698.1|AYG81046.1|3574875_3576234_-|Phosphoglucosamine-mutase
MGRLFGTDGVRGVANSDLTAELALGLSVAAAHVLAEAGTFEGHRPTAVVGRDPRASGEFLEAAVVAGLASAGVDVLRVGVLPTPAVAYLTGVLGADLGVMLSASHNAMPDNGVKFFARGGHKLADELEDRIESIYEQHRTGAPWERPTGAGVGRVRSYKEGFDRYVAHLIGVLPNRLDGLKVVLDEAHGAAARVSPEAFARAGAEVVTIGAEPDGLNINDGCGSTHLDLLKAAVVEHGADLGIAHDGDADRCLAVDAEGNEVDGDQILAVLALAMREAGTLRGNTVVGTVMSNLGFKIAMEGEGIQLVQTGVGDRYVLESMKEHGYALGGEQSGHVIILDHATTGDGTLTGLMLAARVAATRRTLADLAGVMTRLPQVLVNVPDVDKSRVATSAELGTAVAEAERELGATGRVLLRPSGTEPLVRVMVEAADIEQARSVAGRLADVVKSALG
>CP032698.1|AYG81047.1|3576338_3576857_-|30S-ribosomal-protein-S9
MAETTVETPVEGEETYAEVTTFESEVPVEGEYTTESMASRFGDPQPAAGLGRRKNAIARVRIVPGTGKWKINGRTLEDYFPNKVHQQEVNEPFKVLELDNRYDVIARISGGGVSGQAGALRLGVARALNEADVDNNRAALKKAGFLSRDDRAVERKKAGLKKARKAPQYSKR
>CP032698.1|AYG81048.1|3576901_3577345_-|50S-ribosomal-protein-L13
MRTYSPKPGDITRQWHVIDARDVVLGRLATTAANLLRGKHKPVYAPHMDMGDFVIIINADKVHLSGNKKTQKMAYRHSGYPGGLRSVRYDDLLANNPEKAVEKAIKGMIPKNTLGRQMISKLKVYSGDQHPHAAQQPVPFEITQVAQ
>CP032698.1|AYG81049.1|3577619_3579242_-|putative-ABC-transporter-ATP-binding-protein-YbiT
MGHLEAAHLEYYLPDGRVLLGDASFRVAEGSVVALVGANGAGKTTLLRMISGELQPHGGSVSVSGGLGVMPQFVGSVRDERTVRDLLVSVAQPRIREAAAEVDAAEHLIMTVDDEAAQMKYAQALSDWAEARGYEAETVWDMCTMAALGMPYDKAQFREVRTLSGGEQKRLVLEALLRGPDEVLLLDEPDNYLDVPGKRWLEERLRETRKTVLFVSHDRELLSRAAERIVSLEPSPAGTDVWVHGAGFATYHQARRERFARFEELKRRWDEEHARLKALVLRLRNQAAISPDMASRYHAMQTRFKKFEEAGPPPEPPREQEITMRLRGGRTGVRALTCENLELTGLMKPFSLEVFYGERVAVLGSNGSGKSHFLRLLAGDASVAYTGNWKLGARVVPGHFAQTHAHPELLGRTLVDILWSEHAKDRGAAMSVLRRYELERQGDQPFEKLSGGQQARFQILLLELAGTTALLLDEPTDNLDLESAEALQDGLESYDGTVLAVTHDRWFSKSFDRYLVFGSDGVVRETSEPVWDERRVERAR
>CP032698.1|AYG81050.1|3579298_3580141_+|hypothetical-protein
MSFGQGGPGWGPGDQQTPDWAALADASAARNRRKKWIFIGAGAVATAAVVAVVAAVIVNAGSSDDGKSTSALPSPPALPSDSAQPGPSFSHVAPPPPPNPYDFVASAKKDTAPLGADTLFPGQSLTLGSGAYAKGPTGKVTDCASVTQGSLGATLANNGCRQVIRATFTKDGVAVTVGVAVFDTDVQATKAKEQASGGIASLSGSGVNTFCRGGSVCRNTTNSYGRYAYFTISGFTNGKNVTQGDTAVFAAGNDLAKFTFDQIVARGRNQASAAAARPAA
>CP032698.1|AYG81051.1|3580111_3580984_-|tRNA-pseudouridine-synthase-A
MSDEVEPGLVRVRLDLSYDGKDFSGWARQPLGRRTVQGEIEDALRTVTRSDVSYDLTVAGRTDAGVHARGQVAHVDLPQEVWAEHREKLLRRMAGRLPHDVRIWRIAEAPSGFNARFSAIWRRYAYRVTDNVGGVDPLLRGHVLWHDWELDVEAMNAASAALLGEHDFAAYCKKREGATTIRTLQELSWARGDDGIVTATVRADAFCHNMVRSLVGALLYVGDGHRGVEWPGKVLAAAVRDSSVHVVKPHGLTLEEVGYPADELLAARSKEARNLRTLPGSSGGGPGGCC

Crispr_ID: CP032698_24

• CRISPR_ID: CP032698_24
• CRISPR_location: 3628513-3628611
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_24

Consensus_repeat	Method
CCTTTGCCCACCCACCCGCCCGT	CRISPRCasFinder

spacers of CP032698_24

>24.1|3628536|53|CP032698|CRISPRCasFinder
GCAGCGGGTTGGAGGGTTCCGGCCCCCTGGGGCTCCGCCCCAGACCCCGAGCC

CRISPR arrays and Neighbor proteins around CP032698_24

CRISPR arrays

The CRISPR arrays of CP032698_24

>merge|CP032698|24|3628513-3628611|CRISPRCasFinder
CCTTTGCCCACCCACCCGCCCGTGCAGCGGGTTGGAGGGTTCCGGCCCCCTGGGGCTCCGCCCCAGACCCCGAGCCCCTTCGCCCACCCACCCGCCCGT

>CP032698|24|19|3628513-3628611|CRISPRCasFinder
CCTTTGCCCACCCACCCGCCCGT	GCAGCGGGTTGGAGGGTTCCGGCCCCCTGGGGCTCCGCCCCAGACCCCGAGCC
CCTTCGCCCACCCACCCGCCCGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81098.1|3623728_3624163_-|50S-ribosomal-protein-L11	unknown	unknown	gnl|CDD|234661
CP032698.1|AYG81112.1|3637118_3637775_+|putative-sugar-epimerase-YhfK	unknown	unknown	gnl|CDD|187554
CP032698.1|AYG81101.1|3626090_3627338_+|Aspartate-aminotransferase	unknown	unknown	gnl|CDD|235596
CP032698.1|AYG81103.1|3628939_3629536_-|Fatty-acid-metabolism-regulator-protein	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG81106.1|3631935_3633372_-|Multidrug-resistance-protein-Stp	unknown	unknown	gnl|CDD|129794
CP032698.1|AYG81099.1|3624342_3625329_-|Transcription-termination/antitermination-protein-NusG	unknown	unknown	gnl|CDD|180161
CP032698.1|AYG81111.1|3635790_3637062_+|N-isopropylammelide-isopropyl-amidohydrolase	unknown	unknown	gnl|CDD|238618
CP032698.1|AYG81094.1|3620392_3620776_-|50S-ribosomal-protein-L7/L12	unknown	unknown	gnl|CDD|234671
CP032698.1|AYG81100.1|3625364_3625685_-|Protein-translocase-subunit-SecE	unknown	unknown	gnl|CDD|236066
CP032698.1|AYG81093.1|3616292_3619778_-|DNA-directed-RNA-polymerase-subunit-beta	unknown	unknown	gnl|CDD|234749
CP032698.1|AYG81107.1|3633438_3633990_-|hypothetical-protein	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG81104.1|3629624_3630257_+|hypothetical-protein	unknown	unknown	gnl|CDD|187555
CP032698.1|AYG81110.1|3635116_3635281_-|50S-ribosomal-protein-L33-2	unknown	unknown	gnl|CDD|234783
CP032698.1|AYG81108.1|3634070_3634505_-|hypothetical-protein	unknown	unknown	gnl|CDD|239537
CP032698.1|AYG81097.1|3622890_3623613_-|50S-ribosomal-protein-L1	unknown	unknown	gnl|CDD|180071
CP032698.1|AYG81095.1|3620889_3621420_-|50S-ribosomal-protein-L10	unknown	unknown	gnl|CDD|234632
CP032698.1|AYG81096.1|3621753_3622701_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81109.1|3634506_3634959_-|hypothetical-protein	unknown	unknown	gnl|CDD|379194
CP032698.1|AYG81102.1|3627482_3628502_+|Aminodeoxyfutalosine-deaminase	unknown	unknown	gnl|CDD|273619
CP032698.1|AYG81105.1|3630377_3631601_-|UDP-N-acetylenolpyruvoylglucosamine-reductase	unknown	unknown	gnl|CDD|237552

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81098.1|3623728_3624163_-|50S-ribosomal-protein-L11	gnl|CDD|234661	PRK00140, rplK, 50S ribosomal protein L11; Validated.	3.96891e-95
CP032698.1|AYG81112.1|3637118_3637775_+|putative-sugar-epimerase-YhfK	gnl|CDD|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.68246e-54
CP032698.1|AYG81101.1|3626090_3627338_+|Aspartate-aminotransferase	gnl|CDD|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
CP032698.1|AYG81103.1|3628939_3629536_-|Fatty-acid-metabolism-regulator-protein	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.95906e-11
CP032698.1|AYG81106.1|3631935_3633372_-|Multidrug-resistance-protein-Stp	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	6.74923e-86
CP032698.1|AYG81099.1|3624342_3625329_-|Transcription-termination/antitermination-protein-NusG	gnl|CDD|180161	PRK05609, nusG, transcription antitermination protein NusG; Validated.	7.27104e-78
CP032698.1|AYG81111.1|3635790_3637062_+|N-isopropylammelide-isopropyl-amidohydrolase	gnl|CDD|238618	cd01293, Bact_CD, Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi, but not mammalian cells. The bacterial enzymes, but not the fungal enzymes, are related to the adenosine deaminases (ADA). The bacterial enzymes are iron dependent and hexameric.	1.75753e-84
CP032698.1|AYG81094.1|3620392_3620776_-|50S-ribosomal-protein-L7/L12	gnl|CDD|234671	PRK00157, rplL, 50S ribosomal protein L7/L12; Reviewed.	6.38772e-43
CP032698.1|AYG81100.1|3625364_3625685_-|Protein-translocase-subunit-SecE	gnl|CDD|236066	PRK07597, secE, preprotein translocase subunit SecE; Reviewed.	1.39814e-18
CP032698.1|AYG81093.1|3616292_3619778_-|DNA-directed-RNA-polymerase-subunit-beta	gnl|CDD|234749	PRK00405, rpoB, DNA-directed RNA polymerase subunit beta; Reviewed.	0
CP032698.1|AYG81107.1|3633438_3633990_-|hypothetical-protein	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.46645e-09
CP032698.1|AYG81104.1|3629624_3630257_+|hypothetical-protein	gnl|CDD|187555	cd05244, BVR-B_like_SDR_a, biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs. Human BVR-B catalyzes pyridine nucleotide-dependent production of bilirubin-IX beta during fetal development; in the adult BVR-B has flavin and ferric reductase activities. Human BVR-B catalyzes the reduction of FMN, FAD, and riboflavin. Recognition of flavin occurs mostly by hydrophobic interactions, accounting for the broad substrate specificity. Atypical SDRs are distinct from classical SDRs. BVR-B does not share the key catalytic triad, or conserved tyrosine typical of SDRs. The glycine-rich NADP-binding motif of BVR-B is GXXGXXG, which is similar but not identical to the pattern seen in extended SDRs. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.53218e-52
CP032698.1|AYG81110.1|3635116_3635281_-|50S-ribosomal-protein-L33-2	gnl|CDD|234783	PRK00504, rpmG, 50S ribosomal protein L33; Validated.	6.76347e-22
CP032698.1|AYG81108.1|3634070_3634505_-|hypothetical-protein	gnl|CDD|239537	cd03453, SAV4209_like, SAV4209_like. Similar in sequence to the Streptomyces avermitilis SAV4209 protein, with a hot dog fold that is similar to those of (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.	6.49609e-56
CP032698.1|AYG81097.1|3622890_3623613_-|50S-ribosomal-protein-L1	gnl|CDD|180071	PRK05424, rplA, 50S ribosomal protein L1; Validated.	1.3717e-146
CP032698.1|AYG81095.1|3620889_3621420_-|50S-ribosomal-protein-L10	gnl|CDD|234632	PRK00099, rplJ, 50S ribosomal protein L10; Reviewed.	4.66208e-68
CP032698.1|AYG81109.1|3634506_3634959_-|hypothetical-protein	gnl|CDD|379194	pfam13452, MaoC_dehydrat_N, N-terminal half of MaoC dehydratase. It is clear from the structures of bacterial members of MaoC dehydratase, pfam01575, that the full-length functional dehydratase enzyme is made up of two structures that dimerize to form a whole. Divergence of the N- and C- monomers in higher eukaryotes has led to two distinct domains, this one and MaoC_dehydratas. However, in order to function as an enzyme both are required together.	5.03914e-38
CP032698.1|AYG81102.1|3627482_3628502_+|Aminodeoxyfutalosine-deaminase	gnl|CDD|273619	TIGR01430, Putative_adenosine/adenine_deaminase, adenosine deaminase. This family includes the experimentally verified adenosine deaminases of mammals and E. coli. Other members of this family are predicted also to be adenosine deaminase, an enzyme of nucleotide degradation. This family is distantly related to AMP deaminase.	1.67314e-143
CP032698.1|AYG81105.1|3630377_3631601_-|UDP-N-acetylenolpyruvoylglucosamine-reductase	gnl|CDD|237552	PRK13903, murB, UDP-N-acetylmuramate dehydrogenase.	0

Protein sequences

>CP032698.1|AYG81102.1|3627482_3628502_+|Aminodeoxyfutalosine-deaminase
MEHVRDVSALPKAHLHLHFTGSMRPATLLELADKYGVRLPDALTGAEPPKLRATDERGWFRFQRLYDAARSCLRSPEDIQRLVREAAEEDVKDGSGWLEIQVDPTSYAPLLGGLIPALEIILDAVDSASRETGLGMRVVVAANRMKHPLDARTLARLAVRYADRGVVGFGLSNDERRGMARDFDRAFAIAREGGLLAAPHGGELSGPASVRDCLDDLHARRIGHGVRAAEDPRLLRRLAERGVTCEVCPASNVALGVYEKPEDVPLRVLYDAGVPMALGADDPLLFGSRLAAQYELARRHHGFDDPELAELARQSIRACTAPPDTQEKLLSGVDAWLAS
>CP032698.1|AYG81101.1|3626090_3627338_+|Aspartate-aminotransferase
MARMSAATPPPSSPTERRVSARIGAISESATLAVDAKAKALKAAGRPVIGFGAGEPDFPTPDYIVEAAVEACRNPKYHRYTPAGGLPELKAAIAAKTLRDSGYEVDASQVLVTNGGKQAIYEAFAAILDPGDEVIVPAPYWTTYPESIRLAGGVPVDVVADETTGYRVSVEQLEAARTERTKVVLFVSPSNPTGAVYSEAEAEAIGRWAVEHGLWVMTDEIYEHLVYGSATFTSLPAIVPELRDKCVVVNGVAKTFAMTGWRVGWIIGPKDVVKAATNLQSHATSNVSNVAQVAALAAVSGNLDAVAAMREAFDRRRRTMVRMLSEIDGVICPTPEGAFYAYPSVKGLLGKEIRGKRPATSAELAALILDETEVAVVPGEAFGTPGYLRLSYALGDEDLVEGVSRIQKLLAEARD
>CP032698.1|AYG81100.1|3625364_3625685_-|Protein-translocase-subunit-SecE
MTRNQVRSVTDAVGSIDMPDAQDEAAESKDSKKKARKGGKRGKKGPLGRLALFYRQVVAELRKVVWPTRSQLTTYTTVVIVFVVIMIGIVTLIDSGFSQVVKYVFG
>CP032698.1|AYG81099.1|3624342_3625329_-|Transcription-termination/antitermination-protein-NusG
MFHPICSQEEAATVSDPNLNDASESVESVEDELEIIEAADEDEAEAADAAAGEAAEEAALNVESDDAESDEDEAAEASDVTDEVASDEDETEGTASDDESAEPTDSVETDSAEDEEPAEPAAPVDPVEALRQELRFLPGEWYVIHTYAGYEKRVKANLEQRAVSLNVEEFIYQAEVPEEEIVQIKNGERKNVRQNKLPGYVLVRMDLTNESWGVVRNTPGVTGFVGNAYDPYPLTLDEIVKMLAPEAEEKAAREAAEAEGKPAPQRKVEVQVLDFEVGDSVTVTDGPFATLQATINEINADSKKVKGLVEIFGRETPVELSFDQIQKN
>CP032698.1|AYG81098.1|3623728_3624163_-|50S-ribosomal-protein-L11
MPPKKKKVTGLIKLQINAGAANPAPPVGPALGQHGVNIMEFCKAYNAATESQRGWVIPVEITVYEDRSFTFITKTPPAAKMILKAAGVQKGSGEPHKTKVAKITQAQVREIATTKLPDLNANDLDAASKIIAGTARSMGITVEG
>CP032698.1|AYG81097.1|3622890_3623613_-|50S-ribosomal-protein-L1
MKRSKTLRAADAKIDADKLYAPLEAVRLAKETSTTKFDGTVEVAFRLGVDPRKADQMVRGTVNLPHGTGKTARVLVFATGDRAEAALAAGADIVGSDELIDEVAKGRLDFDAVVATPDLMGKVGRLGRVLGPRGLMPNPKTGTVTPDVAKAVEEIKGGKIEFRVDKHSNLHFIIGKVSFDDTKLVENYGAALEEILRLKPSAAKGRYIKKATITTTMGPGISLDSNRTRNLLVEEDPAAV
>CP032698.1|AYG81096.1|3621753_3622701_-|hypothetical-protein
MSGSFKRAGISFAAVAVLVAGAAACQGGDGKKAAGAPEKAAGQSSSADARTALQAAYKKTAAAKSAKVTMKMSVPSIVGAGVGDMEMTGIQAWNPSAMDFTMTTPALKGMPDAPDKIRTVMLNNVMYMDMGAEAAKDNGGKRWMKMDLGALAKDGGGGLAQQMTGGAQNQDPAQQLALLTDSPHVRHLGSEQIDGAPAEHYKGTLTLEEALATNKSLDGLSGQERQKFIDAMKGAGIKAYDTELWIAKSGYPVRMDVGIDSPQGKLTMSAHYSDYGTTSAVRAPAAAETYDFADSLKDLGKGDLGKGDLGKGGAA
>CP032698.1|AYG81095.1|3620889_3621420_-|50S-ribosomal-protein-L10
MARPDKAAAVAELTDQFRSSNAAVLTEYRGLTVTQLEKLRRSLGENAQYAVVKNTLTKIAANEAGITSLDDHFAGPTAVAFITGDPVESAKGLRDFAKENPNLIIKGGVLDGKALSADEIKQLADLESREVLLSKLAGAFKGKQSQAASLFQALPSKFVRTAEALRVKLAEQGGAE
>CP032698.1|AYG81094.1|3620392_3620776_-|50S-ribosomal-protein-L7/L12
MAKLSQEDLLAQFEEMTLIELSEFVKAFEEKFDVTAAAAVAVAGPAGPAAPADAVEEQDEFDVILEGAGDKKIQVIKVVRELTSLGLKEAKDLVDGAPKPVLEKVAKEAADKAAESLKAAGASVTVK
>CP032698.1|AYG81093.1|3616292_3619778_-|DNA-directed-RNA-polymerase-subunit-beta
MAASRNASTSNTNNGASTAPLRISFAKIKEPLEVPNLLALQTESFDWLLGNAAWKSRVEAALESGQDVPTKSGLEEIFEEISPIEDFSGSMSLTFRDHRFEPPKNSIDECKERDFTFAAPLFVTAEFTNNETGEIKSQTVFMGDFPLMTNKGTFVINGTERVVVSQLVRSPGVYFDSNIDKTSDKDIFTAKIIPSRGAWLEMEIDKRDMVGVRIDRKRKQSVTVLLKALGWTTEQILEEFGEYESMRATLEKDHTQGQDDALLDIYRKLRPGEPPTREAAQTLLENLYFNPKRYDLAKVGRYKVNKKLGADEPLDAGVLTTDDVIATIKYLVKLHAGETETVGESGRNIVVETDDIDHFGNRRLRNVGELIQNQVRTGLARMERVVRERMTTQDVEAITPQTLINIRPVVASIKEFFGTSQLSQFMDQNNPLSGLTHKRRLSALGPGGLSRERAGFEVRDVHPSHYGRMCPIETPEGPNIGLIGSLASYGRVNAFGFIETPYRKVVDGQVTDEVDYVTADEEDRFVIAQANAALSDDMRFTEPRVLVRRRGGEVDYVPGTEVDYMDVSPRQMVSVATAMIPFLEHDDANRALMGANMMRQAVPLITSEAPLVGTGMEYRCAVDAGDVIKAEKAGVVQEVSADYITVANDDGTYTTYRIAKFARSNQGTSVNQKVVVDEGARVIEGQVLADGPATREGEMALGKNLLVAFMPWEGHNYEDAIILSQRLVQDDVLSSIHIEEHEVDARDTKLGPEEITRDIPNVSEEVLADLDERGIIRIGAEVVAGDILVGKVTPKGETELTPEERLLRAIFGEKAREVRDTSLKVPHGEIGKVIGVRVFDREEGDELPPGVNQLVRVYVAQKRKITDGDKLAGRHGNKGVISKILPIEDMPFLEDGTPVDIILNPLGVPSRMNPGQVLEIHLGWLASRGWDVSGLADDWAQRLQAIGADQVAAGTNVATPVFDGAREDEITGLFEATIPNRDGDRLVQPSGKANLFDGRSGEPFPDPISVGYMYILKLHHLVDDKLHARSTGPYSMITQQPLGGKAQFGGQRFGEMEVWALEAYGAAYALQELLTIKSDDVTGRVKVYEAIVKGENIPEPGIPESFKVLIKEMQSLCLNVEVLSSDGMSIEMRDTDEDVFRAAEELGIDLSRREPSSVEEV
>CP032698.1|AYG81103.1|3628939_3629536_-|Fatty-acid-metabolism-regulator-protein
MQSPPARVRIVDAAHELMLTIGLARATTKEIAKAAGCSEAALYKHFASKEDLFVTVLKERLPQLGPLVARLTEEPGERSVEANLTEIARQAALFYAESFPIAASLYADPQLKRRHDEALRELGTGPHVPIDGVDAYLRAERRAGRIGADTDTYAAASLLLGACAQRAFAYDMTPGGRGPRSLEEFARGVAGVLLRGLA
>CP032698.1|AYG81104.1|3629624_3630257_+|hypothetical-protein
MRLTVFGATGGIGRHVVQQALASGHEVTAVVRDPARFSVQGKGLEVFQADLTDPESLREAVAGRHAVLSGLGARKRSDAGITTRLTRSVLAAMEAEGTRRLVVVSAAPVGPEAPGDGLLDRAMRSMISAVLKDVYVDLAAMEAELAASATDWTSVRPPKLTDKPLTGTYRRVVGGTPKAARTIARADVAHAMLACVDDPATVKRGVGVAY
>CP032698.1|AYG81105.1|3630377_3631601_-|UDP-N-acetylenolpyruvoylglucosamine-reductase
MRRYPGAFTPPTTHGALRTAEATTPARRVCPHCRPQVGAPQRPAPHTTTHPRTLVPVQELHDAPLAPLTTLRLGGPADRLVTATTDAEVVAAVREADDSGTPLLIIGGGSNLLIGDKGFAGTALRIATRGFELDGTRLELAAGEVWSDAVARSVEAGLAGIECLAGIPGSAGATPIQNVGAYGQEVSSTITHVVTYDRRERTTVTLTNAECDFSYRHSRFKQHPDRYVVLRVVFELEDAGGLSAPVKYAETARTLGVAPGERVPAATARETVLKLRAGKGMVLDPEDHDTWSAGSFFTNPILPNEAYETFLARAQERLGADVTPPAWPVGADRTKTSAAWLIDKAGFTKGYGTGPARISTKHTLALTNRGSATTEDLLALAREVVAGVELAFGVTLVNEPVAVGVEI
>CP032698.1|AYG81106.1|3631935_3633372_-|Multidrug-resistance-protein-Stp
MSDQQNPKGTKGRAGWALLVTSVAGFMAALDNLVVTTALPSIREDLGGGLDDLEWTVSAYTLTFAVLLMFGATLGDRFGRRRLFITGLTIFTGASAGAALAPGIDGLIAARAIQGVGAAIMMPLTLTLLTAAVPAAKRGMVYGIWSAVNGLAVASGPLIGGTLTEHASWQWIFWLNVPLGLLTIPLARLRLNESYGTGARLDITGTVLASTGLFGIVYALIRGNPDGWTSATVLTGLIAGGALVAAFVVHGTRSANPMLPMRLFRSRAFSAINAASLLMFVGMFGSIFLLSQFLQNVIGYSPTEAGLRMLPWTGMPMIAAPIAGYLSDRIGGRPVVATGLALQATGLAWFALIMAPDVSYTAQLPALIISGIGMGMYFAPAANLAMCSVRPSEQGIASGANNALREIGGALGIAVLASVFSAQGGYGSAQAFTDGLAPALWVGAAAVALAAAAAVLIPRRPTRAPVQEAAEVRDLAAP
>CP032698.1|AYG81107.1|3633438_3633990_-|hypothetical-protein
MVRMSAEERRESVIRAAMVEFARSGYHGTSTEAIAKRVGVSQPYLFRLFANKQAIFQAAAGRCVAETAEVFRDAAEGLTGEEALHAMGAAYRKLIAEDRDKLLLQMQTYVAVAAAEAAGDHEFGRAMRAAWTELYDTVHLALGADTAETTTFLAYGMLINTLVALGFPPEDRVWKGFQESQPN
>CP032698.1|AYG81108.1|3634070_3634505_-|hypothetical-protein
MTAKIRYEDVEPGTELPAASFPVTRATLVQYAGASGDFNPIHWNERFAKEVGLPDVIAHGMFTMAEAVRVVTDWVGDPGAVSEYGVRFTKPVIVPNDDTGALIEVTAKVAAKLDDEARTVRVDITAMSAGQKVLGMSRAVVRLA
>CP032698.1|AYG81109.1|3634506_3634959_-|hypothetical-protein
MALDQSFVGRTYPPTAPYEVGREKIREFAVAVGDDNPAYTDPEAAKALGHTDVIAPPTFVFAITFSAAGQVIQDPQLGLDYSRVVHGDQKFAYSRPVRAGDRLTVTSTIEAIKSLAGNDILDIRGEVHDEAGEHVVTAWTKLVSRAAEGA
>CP032698.1|AYG81110.1|3635116_3635281_-|50S-ribosomal-protein-L33-2
MAATDVRPKITLACVECKERNYITKKNRRNNPDRLEMKKHCPRCNSHTAHRETR
>CP032698.1|AYG81111.1|3635790_3637062_+|N-isopropylammelide-isopropyl-amidohydrolase
MSDSHQQPAHSPGTGEGPDPTSGSSLLLCGARLADGRTVDVRLGGGRIEAVGTVGSLAAQGASRVDLNGFLLLPAPVEPHAHSDTALTAFSAEGPVSYAVEEVQRRATEAALLQLGHGATALRSHVRIDEVGGLDPLEAVLQTRRSLRGLTELAVVAVPRLLTGVAGADGLAMLRDAVKMGASVVGGCPDLDADPAGYAEAVLELAAEHGCAVDLHTDGADPARVARLAAMSGGLRPGVTIGPCGGLSRLPRDTAARAADQLASAGVTVTCLPQGGCGMTDRQGAAPVRLLRAAGVRLAAGSGALRDVANPVGRGDPLEAAYLLASQAGLRPEDAYAAISTVARQSMGLPEVRVEAGFPAELLAVRGERIAGVLSLAYSRIVVHRGRVVARTSAVREYCDSAAAVALDLPRQGRSEHGRGEPG
>CP032698.1|AYG81112.1|3637118_3637775_+|putative-sugar-epimerase-YhfK
MRIVIAGGHGQIALRLERLLAARGDEVAGIIRKPEQADDLRRAGAEPVVLDLESATVDAVAEVLRAADAVVFAAGAGPGSDASRKETVDRAAAVLLADAAERAGVRRYVIVSSMGADSAHRGDEVFDDYLRAKGAADDAVRSRTGLDWTVLRPGMLTDDAGKGLVTLAASTGRGTIPRDDVAAVLAELVDTPATAGLTLELISGSTPVTVAVKGVAGN

Crispr_ID: CP032698_25

• CRISPR_ID: CP032698_25
• CRISPR_location: 3679799-3679938
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_25

Consensus_repeat	Method
GTTAGGGGCGCGGGGAACTGCGCGAG	PILER-CR

spacers of CP032698_25

>25.1|3679825|37|CP032698|PILER-CR
CAAAAACCCGTCTTCGCCCGCAGACCGTACGGGGCTG
>25.2|3679888|29|CP032698|PILER-CR
CCTCTCGACCCTGCGGACCGTGCCCGCTT

CRISPR arrays and Neighbor proteins around CP032698_25

CRISPR arrays

The CRISPR arrays of CP032698_25

>merge|CP032698|25|3679799-3679938|PILER-CR
CTCGCGCAGTTCCCCGCGCCCCCAAAAACCCGTCTTCGCCCGCAGACCGTACGGGGCTGATCGCGCAGTTCCCCGCGCCCTTAACCCTCTCGACCCTGCGGACCGTGCCCGCTTCTCGCGCAGTTCCTCGCGCCCCTAGC

>CP032698|25|7|3679799-3679938|PILER-CR
CTCGCGCAGTTCCCCGCGCCCCCAAA	AACCCGTCTTCGCCCGCAGACCGTACGGGGCTGATCG
CGCAGTTCCCCGCGCCCTTAACCCTC	TCGACCCTGCGGACCGTGCCCGCTTCTCG
CGCAGTTCCTCGCGCCCCTAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81142.1|3667218_3667755_-|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|379883
CP032698.1|AYG81157.1|3686615_3687290_-|NADH-quinone-oxidoreductase-subunit-I	unknown	unknown	gnl|CDD|235637
CP032698.1|AYG81143.1|3667822_3668089_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81144.1|3667983_3668889_-|hypothetical-protein	unknown	unknown	gnl|CDD|224196
CP032698.1|AYG81161.1|3692490_3693324_-|NADH-quinone-oxidoreductase-subunit-E	unknown	unknown	gnl|CDD|181024
CP032698.1|AYG81155.1|3685498_3685798_-|NADH-quinone-oxidoreductase-subunit-11	unknown	unknown	gnl|CDD|180218
CP032698.1|AYG81152.1|3680313_3681966_-|NADH-quinone-oxidoreductase-subunit-N	unknown	unknown	gnl|CDD|235603
CP032698.1|AYG81150.1|3676168_3677395_+|hypothetical-protein	unknown	unknown	gnl|CDD|215461
CP032698.1|AYG81154.1|3683537_3685484_-|NADH-quinone-oxidoreductase-subunit-L	unknown	unknown	gnl|CDD|235836
CP032698.1|AYG81151.1|3677755_3679618_-|ATP-dependent-DNA-helicase-RecQ	unknown	unknown	gnl|CDD|273594
CP032698.1|AYG81158.1|3687282_3688635_-|NADH-quinone-oxidoreductase-subunit-H	unknown	unknown	gnl|CDD|235692
CP032698.1|AYG81145.1|3668875_3669826_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	unknown	unknown	gnl|CDD|224054
CP032698.1|AYG81148.1|3672590_3673502_+|Di-/tripeptide-transporter	unknown	unknown	gnl|CDD|340904
CP032698.1|AYG81156.1|3685794_3686619_-|NADH-quinone-oxidoreductase-subunit-J	unknown	unknown	gnl|CDD|235844
CP032698.1|AYG81149.1|3673512_3675513_+|Cocaine-esterase	unknown	unknown	gnl|CDD|225487
CP032698.1|AYG81153.1|3681962_3683534_-|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl|CDD|235622
CP032698.1|AYG81160.1|3691129_3692491_-|NADH-quinone-oxidoreductase-subunit-F	unknown	unknown	gnl|CDD|131014
CP032698.1|AYG81147.1|3671401_3672412_-|Octaprenyl-diphosphate-synthase	unknown	unknown	gnl|CDD|173833
CP032698.1|AYG81159.1|3688631_3691133_-|NADH-quinone-oxidoreductase-subunit-G	unknown	unknown	gnl|CDD|236118
CP032698.1|AYG81146.1|3669934_3671161_-|Outer-membrane-lipoprotein-carrier-protein	unknown	unknown	gnl|CDD|225390

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81142.1|3667218_3667755_-|putative-HTH-type-transcriptional-regulator	gnl|CDD|379883	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal. This family of bacterial transcriptional repressors is characterized by the short approximately 50 amino acid stretch of residues constituting the helix-turn-helix DNA binding motif, around the YRFhY motif. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. Another target protein is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	1.30627e-24
CP032698.1|AYG81157.1|3686615_3687290_-|NADH-quinone-oxidoreductase-subunit-I	gnl|CDD|235637	PRK05888, PRK05888, NADH-quinone oxidoreductase subunit NuoI.	4.13181e-81
CP032698.1|AYG81145.1|3668875_3669826_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	3.44518e-99
CP032698.1|AYG81144.1|3667983_3668889_-|hypothetical-protein	gnl|CDD|224196	COG1277, NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component [General function prediction only].	4.45195e-09
CP032698.1|AYG81161.1|3692490_3693324_-|NADH-quinone-oxidoreductase-subunit-E	gnl|CDD|181024	PRK07539, PRK07539, NADH-quinone oxidoreductase subunit NuoE.	4.98107e-86
CP032698.1|AYG81155.1|3685498_3685798_-|NADH-quinone-oxidoreductase-subunit-11	gnl|CDD|180218	PRK05715, PRK05715, NADH-quinone oxidoreductase subunit NuoK.	9.3625e-44
CP032698.1|AYG81152.1|3680313_3681966_-|NADH-quinone-oxidoreductase-subunit-N	gnl|CDD|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	1.96003e-179
CP032698.1|AYG81150.1|3676168_3677395_+|hypothetical-protein	gnl|CDD|215461	PLN02856, PLN02856, fumarylacetoacetase.	1.39989e-151
CP032698.1|AYG81154.1|3683537_3685484_-|NADH-quinone-oxidoreductase-subunit-L	gnl|CDD|235836	PRK06590, PRK06590, NADH:ubiquinone oxidoreductase subunit L; Reviewed.	0
CP032698.1|AYG81151.1|3677755_3679618_-|ATP-dependent-DNA-helicase-RecQ	gnl|CDD|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
CP032698.1|AYG81158.1|3687282_3688635_-|NADH-quinone-oxidoreductase-subunit-H	gnl|CDD|235692	PRK06076, PRK06076, NADH-quinone oxidoreductase subunit NuoH.	7.74842e-169
CP032698.1|AYG81159.1|3688631_3691133_-|NADH-quinone-oxidoreductase-subunit-G	gnl|CDD|236118	PRK07860, PRK07860, NADH dehydrogenase subunit G; Validated.	0
CP032698.1|AYG81148.1|3672590_3673502_+|Di-/tripeptide-transporter	gnl|CDD|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	9.57276e-49
CP032698.1|AYG81156.1|3685794_3686619_-|NADH-quinone-oxidoreductase-subunit-J	gnl|CDD|235844	PRK06638, PRK06638, NADH-quinone oxidoreductase subunit J.	9.78883e-73
CP032698.1|AYG81149.1|3673512_3675513_+|Cocaine-esterase	gnl|CDD|225487	COG2936, COG2936, Predicted acyl esterases [General function prediction only].	1.27018e-107
CP032698.1|AYG81153.1|3681962_3683534_-|NADH-quinone-oxidoreductase-subunit-M	gnl|CDD|235622	PRK05846, PRK05846, NADH:ubiquinone oxidoreductase subunit M; Reviewed.	0
CP032698.1|AYG81160.1|3691129_3692491_-|NADH-quinone-oxidoreductase-subunit-F	gnl|CDD|131014	TIGR01959, NADH-quinone_oxidoreductase_subunit_F, NADH-quinone oxidoreductase, F subunit. This model describes the F chain of complexes that resemble NADH-quinone oxidoreductases. The electron acceptor is a quinone, ubiquinone, in mitochondria and most bacteria, including Escherichia coli, where the recommended gene symbol is nuoF. This family does not have any members in chloroplast or cyanobacteria, where the quinone may be plastoquinone and NADH may be replaced by NADPH, nor in Methanosarcina, where NADH is replaced by F420H2. [Energy metabolism, Electron transport].	0
CP032698.1|AYG81147.1|3671401_3672412_-|Octaprenyl-diphosphate-synthase	gnl|CDD|173833	cd00685, Trans_IPPS_HT, Trans-Isoprenyl Diphosphate Synthases, head-to-tail. These trans-Isoprenyl Diphosphate Synthases (Trans_IPPS) catalyze head-to-tail (HT) (1'-4) condensation reactions. This CD includes all-trans (E)-isoprenyl diphosphate synthases which synthesize various chain length (C10, C15, C20, C25, C30, C35, C40, C45, and C50) linear isoprenyl diphosphates from precursors, isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). They catalyze the successive 1'-4 condensation of the 5-carbon IPP to allylic substrates geranyl-, farnesyl-, or geranylgeranyl-diphosphate. Isoprenoid chain elongation reactions proceed via electrophilic alkylations in which a new carbon-carbon single bond is generated through interaction between a highly reactive electron-deficient allylic carbocation and an electron-rich carbon-carbon double bond. The catalytic site consists of a large central cavity formed by mostly antiparallel alpha helices with two aspartate-rich regions (DDXX(XX)D) located on opposite walls. These residues mediate binding of prenyl phosphates via bridging Mg2+ ions, inducing proposed conformational changes that close the active site to solvent, protecting and stabilizing reactive carbocation intermediates. Farnesyl diphosphate synthases produce the precursors of steroids, cholesterol, sesquiterpenes, farnsylated proteins, heme, and vitamin K12; and geranylgeranyl diphosphate and longer chain synthases produce the precursors of carotenoids, retinoids, diterpenes, geranylgeranylated chlorophylls, ubiquinone, and archaeal ether linked lipids. Isoprenyl diphosphate synthases are widely distributed among archaea, bacteria, and eukareya.	1.33037e-87
CP032698.1|AYG81146.1|3669934_3671161_-|Outer-membrane-lipoprotein-carrier-protein	gnl|CDD|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	3.69799e-11

Protein sequences

>CP032698.1|AYG81151.1|3677755_3679618_-|ATP-dependent-DNA-helicase-RecQ
MSAVGGTQTRTAETEALRTLHRVFGYDAFRGAQGEVIEHVVAGGDAVVLMPTGGGKSLCYQIPALVRPGTGVVVSPLIALMQDQVDALRALGVRAGFINSTQDFDERRTVEAELLAGELDLLYLAPERLRVEATLDLLSRAKISVFAIDEAHCVAQWGHDFRPDYLALSLLGERWADVPRIALTATATDATHREITQRLGMPDARHFVASFDRPNIQYRIVPKNDPKKQLLAFLKEEHDGDAGIVYCLSRASVDKTAQYLSDNGVQAVPYHAGLDGGTRALHQSRFLREEGLVVVATIAFGMGIDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGMPSTAWMAYGLQDVVQQRKMIQGGEGDEAFRRRAAAHLDAMLALCETASCRRAQLLGYFGQEAPAANCGNCDTCLTPPQTWDGTVAAQKALSTVVRLQRERNQKFGAGQIIDILLGRRTAKVIQFDHDALSVFGIGEDLSEPQWRGVVRQLLAQGLLAVEGEYGTLVLTEASGEVLGGRREVRMRTEPEKAVRAASRSASKKSAAAAADLPPEVVPVFEALRAWRGAQAKEAGVPAYVIFHDATLREIATVRPGSLEELSAVGGVGEAKRAKYGEAVLTVLSEAP
>CP032698.1|AYG81150.1|3676168_3677395_+|hypothetical-protein
MSEQSPLELAEGDPFGPHNLPYGVFSTPGHPEDRRVGVRIGDHVLDAGAAAHALGSPYAALLAKPSLNPLLAAGRTAWRDVRRALTAWVTVPAHRPVIEPLLHPLSDVELHLPYEVADYVDFYASEHHATNVGQIFRPDGAALTPNWKHLPIGYHGRSGTIVVSGTEVRRPQGQRKAPTDPAPVFGPSVKLDIEAEVGFVVGTPSELGTPVDLASFDDHVFGLFLLNDWSARDIQAWEYVPLGPFLGKSFATSVSAWVTPLEALTAARVAPPARDFPLLPYLDDSADEVPGGFDLRITVSINGTPVAEPPFASMYWTAAQQLAHMTVNGASLRTGDVYGSGTVSGPERGQRGSLLELTWNGTEPVELPSGKRAFLEDGDEVTLTAWAPGPHGVPVGLGEVRGVITPSP
>CP032698.1|AYG81149.1|3673512_3675513_+|Cocaine-esterase
MHIRTAFPYETRREDVRIPLPDGTLLYARVWRPVTEEPVPALLEYLPYRLTDWTAPRDWQRHPWYAGHGYASVRVDVRGHGCSEGLPGDEYDATELADGVAVVNWLAGQAWCTGKVGMFGISWGGFNSLQVAALAPEPLKAIVTVCSTDDRYDNDVHYMGGSVLAVDMHAWAATMLAFVSRPPDPAFVGEKWREMWLERLESVRPFIHTWLAHQTRDAYWKHGSVCENYPAIDAAVLAVGGWHDPYRDTVLRLVEHLPADRVRGLIGPWSHQYPDRGLPPGPAIGFLQETLRWWDHHLKGEETGVMKEPLLRSWISESHPPATVYAELPGRWVGEPAWPSPHITPLSYALQGAPVQVRSPHHTGLDAGRFFPFGNDADLPPDQRAEDAHSASFDFPVPAGSGPLEILGRPRVTLRLRMDVPFGQAIARLCDVAPDGSSTLVTRGVLNLSARHGRDRADAWPLGATEDVSFDLNGIGHAFAPGHRVRLAVSSAYWPWIWPQADSVGFTLDPAGSSLRLPLRERTSDDVIAFADPEQSEPLGVSHPAPLDEPPPERLVVRDVAKGEWRLEVDPRYGGTRVYPDGLEFTEDARETYTIQSDDPLSARTCSQWHLRLHRPELGWDVTVDTRSSITCDAADFFTSDEVVCREGGEVLFHRTWTRQIPREAG
>CP032698.1|AYG81148.1|3672590_3673502_+|Di-/tripeptide-transporter
MSGTMADAPEESAADQPPPQDDHAIFGQPRGLLTLSGLEVWERFSFLGMQAILPAPAATWAGLGLISAGTGLLKPNVASMVGKLYRTDDERRDAGFALPPEGMRRAVRLMVLGALVIAALAVLLASANAETSILGFHFPAGWYASALGAFEVALAPVVAAVWARTGPRQPHASNKIAFGVVLGGLSFLLMVPATSGHPTDTYRMAVWWIVGSYLLLGLGDVLLETSGMSATTKLAPRAFASQTMSLWFLSLALANGIQAQTVKVYGKVSNPAYFGVNGALAVAVGVAVILAAPWLKRTMHPVH
>CP032698.1|AYG81147.1|3671401_3672412_-|Octaprenyl-diphosphate-synthase
MTVVGPFGLSVRDQALEADVQTGLAAVEAGLLDATKSEVPFITEAAQHLIRAGGKRFRPLIVMLAAQFGDPYAPGVVPSAVVVELTHLATLYHDDVMDEADVRRGVDSANARWGNSVAVLTGDFLFARASHILADLGPEAVRIQAEAFERLVTGQILETAGPRDGRDPVDHYLDVLSGKTGSLVAVSGRFGAMMSGAEESVVDILTQYGERLGTAFQLADDVLDIASDSHESGKTPGTDLREGIPTLPVLHLRAQAAREGRPEDLELVALLDGDLSDDARHAEVLRRLRVHPALEQARRDTVRYAEEARATLAPLPSGYAKSALEELCDAVVHRAG
>CP032698.1|AYG81146.1|3669934_3671161_-|Outer-membrane-lipoprotein-carrier-protein
MAPNDSAQATGEAKEPGAGRRKATRYLVPIGVAGVAAATIGLVPALAASGDPSLPKISAQQLIEKMAASDTQQLSGTMKISTDLGLPGLGSLGAFAPKGGGSDKSAAPEAKLTELASGTHTLRIAADGPDRQKVSILEGAAEYSLIHNGDDVWAYDSASNQAYHSQRGAAGAGKEHGRKAPGEGVPTTPKALADEFLKNVDPTTAVSVDGTAQIAGRDAYQLLIKPKQSGSTIGSVRIAVDAKTGVPLKFTLSPSAGGKAVVDAGFTKVDFSKPSASTFTFSPPKGAKVTEDDGKQERSHKAEQGLPGGLGSFGDAKNAKNSKVIGEGWTAIAAFDTGGKGIPKADESKGGGDAQKFLDSLGTKVSGKFGNGTVFTTRLVNALITDNGTVYVGAVTKDALVAAANSGR
>CP032698.1|AYG81145.1|3668875_3669826_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA
MGNSSAAIETRGLSKRYRGGQLAVNGLDLTVPRGSVFGFLGPNGSGKTTTIRMLMGLIEPTSGSARLLGSPMPAAARTVLPRVGALIEGPALYGFLSGRDNLLRYDAADPTADPRTRAARVTTALDRVGLTSAAGKKARAYSLGMKQRLGLAAALLQRRELLVLDEPTNGLDPQGMREIRSLIRELAKDGTTVFLSSHLLDEIEQVCSHAAVMNQGRLVVQGEVAELAANARGRLAVTTPDPQAAARLLKERGIADVTVVGEDRVTAELPPDDVELADLNAELVRAGVRVRGFVAERASLEDAFVALTGEGFDVAG
>CP032698.1|AYG81144.1|3667983_3668889_-|hypothetical-protein
MSRAEAMDETRRGPEPAPAREPSLLWSLGLFRSELVTVVRRWRTLALLGVLAAVPVLIGIAVKIDTRGGGGGGDGGGGGPAFITQITNNGLFLVFAALAATLPVFLPMAVGVVAGDAMAGEAASGTLRYLLVAPAGRTRLLLAKYASVLAFCLVATLVVAASALAVGALLFPLGDVTTISGTRISFGDGLLRAVMIAGVVAVSLSGMAALGLFVSTLTNSGIAAMASTVGLLITVQILGQIPQLHAIAPYLFPHYWLSFADVLREPVYWDQLVKNFELQALYVAVFGSAAWARFTTKDITA
>CP032698.1|AYG81143.1|3667822_3668089_+|hypothetical-protein
MSSLYEYTRNRIDSLGLWLQQWHRKRNVSCRAVTGVGSHDRSVPIVAELPAARPHAVMSFVVKRAQAAEPKTATYRAWSSKFFTSWSQ
>CP032698.1|AYG81142.1|3667218_3667755_-|putative-HTH-type-transcriptional-regulator
MAALELCAENGYSKVTIEAIAARAGVSKKTIYRWWPTKGAVLLDAVTEQVVSDTTFPDTGDIDVDLCTHIGSLVKVFTAPVAGAAYTGILAELLHDEQLAKAVNEELVIPRVALVYERMRRAQEQGQLPLDIDLPLAVEMLYGPLYYRHALGRPLHEPQRIEELVAYVMRGLRASASS
>CP032698.1|AYG81152.1|3680313_3681966_-|NADH-quinone-oxidoreductase-subunit-N
MSSSAVHSLWTTAAEGKLDKIPAPHIEYAQLAPTLIVVGAAIVGVLVEAFVPRRARYYTQLFLSVVALAAAFAAVVGLAAGGYGTTKAHIAAMGAVAVDGPALFLQGTILLASIVAVFTFAERRLDPVAHGNKVDSFAAQAASVPGSDSEKAAVKAGFTTTEVFPLALFAVSGMLVFPAANDLLTLFVALEVFSLPLYLLCALARRKRLMSQEAAVKYFLLGAFSSAFLLFGIALLYGYAGSVTYSRIADVISGSVQNVDPALAGTMGNDALLLIGGAMLLMGLLFKVGAVPFHMWTPDVYQGAPTPVTGFMAAATKVAAFGALLRLLYVVLPGMSWDWRPVMWGVAIITMLGGAVVAITQTDIKRLLAYSSIAHAGFILAGVIATNADGISSVLFYLAAYSFVTIGAFAVVTLVRDAGGEATHLSKWAGLGRRSPLVAAVFAVFLLAFAGIPLTSGFSGKFAVFKAAAEGGAGALVVIGVISSAVAAFFYIRVIVLMFFSEPKADGPTVAVASPLTMTAIGVGVVVTLVLGVAPQYFLELARHAGVFVR
>CP032698.1|AYG81153.1|3681962_3683534_-|NADH-quinone-oxidoreductase-subunit-M
MSFPLLTATAALPALGAIATAAVPAARRTAAKWLALLVSVGTLALAAIQLGRFEPGGARYQLTESHAWIKDFGVRYELGVDGIGVALIGLTALLIPFIIAAGWHDADPLETHSSRWRPTQGFFALILAVEAMVVLSFEATDVFLFYILFEAMLIPMYFLIGGFGDRAHAGGDEAAATQRSYAAVKFLLYNLVGGLIMLAAVIGLYVVAGSFSLNEIAAARASGSLHMATNTERLLFLGFFFAFAVKAPLWPLHTWLPNAMGEATAPVAVLITAVVDKVGTFAMLRFCLQLFPEASKWATPVIVVLAVISIIYGALLAVGQRDIKRLVAYASISHFGFIIMGIFAMTSQGQSGATLYMVNHGISTAALMLVAGFLISRRGSRLIADYGGVQKVAPVLAGTFLIGGLATLSLPGLAPFVSEFLVLVGTFSRYPVAGVVATLGIVLAALYVLVLYQRTMTGPVKAEVQGMPDLKVRELLVVAPLIGLLIFLGVYPKPLTDIVNPAVRQTMSDVQKKDPNPVVEAAK
>CP032698.1|AYG81154.1|3683537_3685484_-|NADH-quinone-oxidoreductase-subunit-L
MDNLIALLIAAPLLGAAVLLCGGRRLDGIGHWLGTLLAGASFVLGAVLFVDMLGRSADHRTVAKHLFTWVPVEGFQANVGFHLDQLSMTFVLLITGVGTLIHIYSIGYMEHDENRRRFFGYLNLFLAAMLLLVLADNYLLLYVGWEGVGLASYLLIGFWQHKPSAATAAKKAFLVNRVGDMGLSIAIMVMFTTFGSFAFTTVLGEAGGASSGRDTAIGLMLLLAACGKSAQVPLQSWLGDAMEGPTPVSALIHAATMVTAGVYLITRSGAIFNAVPDVQTAVVVVGAVTLLFGAIVGCAKDDIKKALAGSTMSQIGYMILATGLGPIGYAFAIMHLVTHGFFKAGLFLGAGSVMHGMNDEVDMRKYGGLRTYMPVTFVTFGLGYLAIIGFPGLSGFFSKDKIIEAAFAKGGTEGWILGAVTLLGAAITAYYMTRVMVLTFFGEERWRNAKTPSPAEPSVEPAAETRGAHDEPHPHESPKSMTIPMIVLAFGSVFAGGVFGIGDRFVKWLEPVTSFDHGDSPLGEWTVTGATVVCLLIGVGLAVAQYGRKPVPVVAPRGSLLTRAARRDLLQDDFNHVVLVRGGEHLTRSLVYLDHSLVDGVVNGTAASVGGLSGRLRKLQNGFARSYAVSMFGGAVVIIAATLLMRAV
>CP032698.1|AYG81155.1|3685498_3685798_-|NADH-quinone-oxidoreductase-subunit-11
MNPVNYLYLAALLFTIGAAGVLIRRNAIVVFMCVELMLNACNLAFVCFSRLHGNLDGQVIAFFTMVVAAAEVVVGLAIIVSLFRSRHSASVDDASLMKL
>CP032698.1|AYG81156.1|3685794_3686619_-|NADH-quinone-oxidoreductase-subunit-J
MSASTVALAAAASHTSTGEAFQFWVLGTVAVIGALCTILMKKAVHSALCLAATMIILAVFYLANGAYFLGVVQIVVYTGAIMMLFLFVVMLVGVTAADSLKETIKGQRWWAAACGLGFGVLLIAGIANASLKNFNGLGQANANGNVEGLAALIFTKYVFAFEITGALLITSAVGAMVLTHRERTERAKTQREMSEERVRGKHLPPLPAPGVYARHNAVDIAGLLPDGTPSELTVNQTLRGRGQIRDVSQQALDDLKALEQRSEERLGRDEEAVK
>CP032698.1|AYG81157.1|3686615_3687290_-|NADH-quinone-oxidoreductase-subunit-I
MSDKSSAGASGKPGKPGESEDTFLNPVAGFGVTFKAMFKKRLTEQYPEQPKVTAPRFHGRHQLNRHPDGLEKCVGCELCAWACPADAIYVEGADNTDEERYSPGERYGRVYQINYARCILCGLCIEACPTRALTMTNEFELADSSRENLIYTKEQLLAGLDDTMVDSPHAIYPGMNEQDYYRGLVTEAAPGTVRQVALSKGEQPQEAASTFGPEEPASGKVVGA
>CP032698.1|AYG81158.1|3687282_3688635_-|NADH-quinone-oxidoreductase-subunit-H
MITLAAEDLSLFGRDPWWLVFVKAVFCFAFLMVTVLFSIVWERKVVAWMQLRIGPNRHGPWGMLQSLADGIKLMLKEDVIVKRADKVVYVLAPIIAAIPAFMAIAVIPFGPSGNEVSIFGHRTTMQLTDLPIAMLYVLAVASVGIYGIVLAGWSSGSTYPLLGGLRSCAQMISYEIAMGAAFASVFLYSGSMSTSKIVEAQGDRWYIVLLPVSFIIYIITMVGETNRAPFDMPESEGDLVGGFNTEYSSIKFAMFMLAEYVNMVTVSAVATTLFLGGWRAPWPISTFWAGANHGWWPMLWFVIKVQLLLFFFIWLRGTLPRVRYDQLMKLGWKVLIPVSVVWLMLVATVRALRNEGYDFSRIVLYVGGAVVALLLLSFVADMFRGKKQDADAKAPPAAFDPMAGGFPVPPLPGQTLPPVPRRRPRTERELIVSGGADTQSEREGREDDGV
>CP032698.1|AYG81159.1|3688631_3691133_-|NADH-quinone-oxidoreductase-subunit-G
MTVTTSSASSGGGEAAVPPEDLVSLTIDGIDISVPKGTLVIRAAEQLGIEIPRFCDHPLLDPAGACRQCIVEVEGQRKPMASCTITCTDGMVVKSQLSSPVAEKAQRGVMELLLINHPLDCPVCDKGGECPLQNQAMQVGDTDSRFEGKKRTYEKPVPISTQVLLDRERCVLCARCTRFSNQIAGDPMIELIERGALQQVGTGEGDPFESYFSGNTIQICPVGALTSAAYRFRSRPFDLVSSPSVCEHCAGGCATRTDHRRGKVMRRLAAEDPEVNEEWVCDKGRFAFRYAQQRDRLTTPLVRNADGVLETASWPEALEAAAAGLAAARGRAGVLAGGRLTVEDAYAYAKFARIALDTNDIDFRARVHSAEEADFLAARVAGHGRDLDGQGATYTSVERAPAVLLVGFESEEEAPGVFLRLRKAWRKHGQRTFSLATHMTRGLAKAGGTLLPAAPGTETEWLDALAGGVGLDADGAKAAEALRAPGAVLIVGERLAGVPGALTAAVRAASATGAELVWIPRRAGERGAVEAGALPSLLPGGRPATDPRAREEVASAWGVRELPHRYGRDTGQIVEAAVTGELGALLVAGVDPADLPDPARARQALAGSFVVSLELRPTEVTAHADVVLPVAAVAEKPGTFLNWEGRARLFEAALKPEQMTRSLAPTDARVLHMLADALDVRLALPDVRAVRTEMTRLGTWDGPRASQPLESAQPLPRPAAGEAVLAGHRMLLDQGSLQDGDEALAGTRHAAVARLSAATAAESGVKDGDLLQVTGPAGAVQLPLRVSEMPDRVVWLPLNSVGGGVASDTGAVPGGVVRVGPAVTEAPTEVVEA
>CP032698.1|AYG81160.1|3691129_3692491_-|NADH-quinone-oxidoreductase-subunit-F
MTLATEIAGNGNGSSPEKLLAPVLSAFWDQPESWTLETYRRHDGYEGLRKALAMTPDDLIAYVKDSGLRGRGGAGFPTGMKWQFIPQGDGKPHYLVVNADESEPGTCKDIPLLFANPHSLIEGIVIACYAIRSSHAFIYLRGEVVPVLRRLHEAVREAYEAGFLGEDILGSGLNLELTVHAGAGAYICGEETALLDSLEGRRGQPRLRPPFPAVAGLYACPTVVNNVESIASVPAILNRGKDWFKSMGSEKSPGFTLYSLSGHVTGPGQYEAPLGITLRQLLDMSGGMRKGHRLKFWTPGGSSTPMFTDEHLDVPLDYEGVGAAGSMLGTKALQCFDETTCVVRAVTRWTEFYAHESCGKCTPCREGTYWLVQLLRDIEAGKGSMGDLDKLNDIADNINGKSFCALGDGAASPIFSSLKYFRDEYEQHITGKGCPFDPARSTAWADDNTEVNA
>CP032698.1|AYG81161.1|3692490_3693324_-|NADH-quinone-oxidoreductase-subunit-E
MTDIQLGMPQLPAPDYPADVRARLEADGREIVARYPDSRSALLPLLHLVQAEEGYVSRTGMAFCADLLELTTAEVTAVATFYSMYRRKPSGDYQVGVCTNTLCAVMGGDAIFDELKRHLGVGNNETTDDGKVTLEHIECNAACDFAPVVMVNWEFFDNQTPESAKRLVDDLRAGREVEPTRGAPLCTYQETARILAGFPDQRPGAVAATGGAGPASLAGLRLAKGETPGARVVHPRGEGPKDRPQPGSEHLSSHDAPQQTSASDPAHPAGPAAEEGE

Crispr_ID: CP032698_26

• CRISPR_ID: CP032698_26
• CRISPR_location: 3743799-3743883
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_26

Consensus_repeat	Method
TTTAAGGGGCGCGGGGAACTGCGCGA	CRISPRCasFinder

spacers of CP032698_26

>26.1|3743825|33|CP032698|CRISPRCasFinder
CCAGCCACGCACGGCCCGCAGCCGAAAGCGGGT

CRISPR arrays and Neighbor proteins around CP032698_26

CRISPR arrays

The CRISPR arrays of CP032698_26

>merge|CP032698|26|3743799-3743883|CRISPRCasFinder
TTTAAGGGGCGCGGGGAACTGCGCGACCAGCCACGCACGGCCCGCAGCCGAAAGCGGGTTTTGAGGGGCGCGGGGAACTGCGCGA

>CP032698|26|20|3743799-3743883|CRISPRCasFinder
TTTAAGGGGCGCGGGGAACTGCGCGA	CCAGCCACGCACGGCCCGCAGCCGAAAGCGGGT
TTTGAGGGGCGCGGGGAACTGCGCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81203.1|3737772_3737976_+|Cold-shock-like-protein-7.0	unknown	unknown	gnl|CDD|224197
CP032698.1|AYG81202.1|3736598_3737465_-|Chorismate-dehydratase	unknown	unknown	gnl|CDD|270352
CP032698.1|AYG81216.1|3751456_3751906_-|HTH-type-transcriptional-regulator-LrpC	unknown	unknown	gnl|CDD|214628
CP032698.1|AYG81211.1|3746626_3747199_-|hypothetical-protein	unknown	unknown	gnl|CDD|334719
CP032698.1|AYG81217.1|3752048_3752171_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81205.1|3739986_3740994_+|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|378890
CP032698.1|AYG81206.1|3741192_3742344_+|putative-inactive-lipase	unknown	unknown	gnl|CDD|367570
CP032698.1|AYG81218.1|3752167_3752890_-|Flavin-prenyltransferase-UbiX	unknown	unknown	gnl|CDD|223241
CP032698.1|AYG81210.1|3745538_3746216_-|HTH-type-transcriptional-repressor	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG81204.1|3738089_3739766_-|Long-chain-fatty-acid--CoA-ligase-FadD15	unknown	unknown	gnl|CDD|341233
CP032698.1|AYG81200.1|3732991_3735190_-|Serine/threonine-protein-kinase-AfsK	unknown	unknown	gnl|CDD|270916
CP032698.1|AYG81212.1|3747569_3748943_-|C4-dicarboxylate-transport-protein	unknown	unknown	gnl|CDD|366058
CP032698.1|AYG81208.1|3743147_3743645_+|hypothetical-protein	unknown	unknown	gnl|CDD|316352
CP032698.1|AYG81201.1|3735420_3736533_+|hypothetical-protein	unknown	unknown	gnl|CDD|366286
CP032698.1|AYG81207.1|3742366_3743008_-|hypothetical-protein	unknown	unknown	gnl|CDD|133407
CP032698.1|AYG81214.1|3749685_3750228_-|hypothetical-protein	unknown	unknown	gnl|CDD|366181
CP032698.1|AYG81199.1|3731384_3732458_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81213.1|3749329_3749626_-|hypothetical-protein	unknown	unknown	gnl|CDD|379415
CP032698.1|AYG81209.1|3743963_3745154_-|hypothetical-protein	unknown	unknown	gnl|CDD|224748
CP032698.1|AYG81215.1|3750237_3751401_-|Aminodeoxyfutalosine-synthase	unknown	unknown	gnl|CDD|213851

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81203.1|3737772_3737976_+|Cold-shock-like-protein-7.0	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.38642e-36
CP032698.1|AYG81202.1|3736598_3737465_-|Chorismate-dehydratase	gnl|CDD|270352	cd13634, PBP2_Sco4506, The conserved hypothetical protein SCO4506 exhibits the type 2 periplasmic-binidng protein fold. This group includes the SCO4506 protein from Streptomyces coelicolor and related hypothetical proteins. SCO4506 is an ortholog of Ttha1568 (MqnD) from Thermus thermophilies HB8. MqnD is an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. SCO4506 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.51054e-112
CP032698.1|AYG81216.1|3751456_3751906_-|HTH-type-transcriptional-regulator-LrpC	gnl|CDD|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	5.23492e-35
CP032698.1|AYG81211.1|3746626_3747199_-|hypothetical-protein	gnl|CDD|334719	pfam01872, RibD_C, RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis. This domain is found in the C-terminus of RibD/RibG, in combination with pfam00383, as well as in isolation in some archaebacterial proteins. This family appears to be related to pfam00186.	7.95447e-32
CP032698.1|AYG81205.1|3739986_3740994_+|putative-HTH-type-transcriptional-regulator	gnl|CDD|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	1.46484e-46
CP032698.1|AYG81210.1|3745538_3746216_-|HTH-type-transcriptional-repressor	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.27915e-14
CP032698.1|AYG81218.1|3752167_3752890_-|Flavin-prenyltransferase-UbiX	gnl|CDD|223241	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism].	1.51033e-65
CP032698.1|AYG81204.1|3738089_3739766_-|Long-chain-fatty-acid--CoA-ligase-FadD15	gnl|CDD|341233	cd05907, VL_LC_FACS_like, Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases. This family includes long-chain fatty acid (C12-C20) CoA synthetases and Bubblegum-like very long-chain (>C20) fatty acid CoA synthetases. FACS catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, and the formation of a fatty acyl-CoA. Eukaryotes generally have multiple isoforms of LC-FACS genes with multiple splice variants. For example, nine genes are found in Arabidopsis and six genes are expressed in mammalian cells. Drosophila melanogaster mutant bubblegum (BGM) have elevated levels of very-long-chain fatty acids (VLCFA) caused by a defective gene later named bubblegum. The human homolog (hsBG) of bubblegum has been characterized as a very long chain fatty acid CoA synthetase that functions specifically in the brain; hsBG may play a central role in brain VLCFA metabolism and myelinogenesis. Free fatty acids must be "activated" to their CoA thioesters before participating in most catabolic and anabolic reactions.	1.91268e-174
CP032698.1|AYG81200.1|3732991_3735190_-|Serine/threonine-protein-kinase-AfsK	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	8.91998e-88
CP032698.1|AYG81212.1|3747569_3748943_-|C4-dicarboxylate-transport-protein	gnl|CDD|366058	pfam00375, SDF, Sodium:dicarboxylate symporter family.	1.66256e-114
CP032698.1|AYG81208.1|3743147_3743645_+|hypothetical-protein	gnl|CDD|316352	pfam13826, DUF4188, Domain of unknown function (DUF4188).	8.2867e-52
CP032698.1|AYG81201.1|3735420_3736533_+|hypothetical-protein	gnl|CDD|366286	pfam00756, Esterase, Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family.	4.92568e-11
CP032698.1|AYG81207.1|3742366_3743008_-|hypothetical-protein	gnl|CDD|133407	cd04780, HTH_MerR-like_sg5, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 5), N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.32022e-27
CP032698.1|AYG81214.1|3749685_3750228_-|hypothetical-protein	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.30789e-06
CP032698.1|AYG81206.1|3741192_3742344_+|putative-inactive-lipase	gnl|CDD|367570	pfam03583, LIP, Secretory lipase. These lipases are expressed and secreted during the infection cycle of these pathogens. In particular, C. albicans has a large number of different lipases, possibly reflecting broad lipolytic activity, which may contribute to the persistence and virulence of C. albicans in human tissue.	1.24112e-48
CP032698.1|AYG81213.1|3749329_3749626_-|hypothetical-protein	gnl|CDD|379415	pfam14012, DUF4229, Protein of unknown function (DUF4229). This family of integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 95 and 122 amino acids in length.	5.13663e-14
CP032698.1|AYG81209.1|3743963_3745154_-|hypothetical-protein	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	1.74655e-27
CP032698.1|AYG81215.1|3750237_3751401_-|Aminodeoxyfutalosine-synthase	gnl|CDD|213851	TIGR03700, mena_SCO4494, putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family. Members of this protein family appear to be involved in menaquinone biosynthesis by an alternate pathway via futalosine, based on close phylogenetic correlation with known markers of the futalosine pathway, gene clustering in many organisms, and paralogy with the SCO4550 protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	0

Protein sequences

>CP032698.1|AYG81208.1|3743147_3743645_+|hypothetical-protein
MSAKQAPNRTTAAAEGEVVVLLIGMRVNHFWAVHQWVPVGFAMLRMLAELKRDRSRGLLGHVLLTASPRTYYVVQYWESKEKLYAYAHSPQMFHHRAWAILNRKERQGKVRGHVGLWHETYVVPEGSYESIYADMPPFGLAAATGVLPLARRGRTAADRLAHRPA
>CP032698.1|AYG81207.1|3742366_3743008_-|hypothetical-protein
MRLAELSERSGVSAAMIKYYLRQGMLAPGRKVGATTADYDESHLRRLRLVRALIEVGGLTVARAKEVIGYVDDDSLDRTIRLGAALWALPHGPDPDDGDASVAVARVEVDRLLDALGWTTARELGELSPDHRALIVAVATLHRLGYSWDAEFMAPYAELMHRAAVRDLDFVETHPSEEEKVEVAVAATVLFDPVLRALHRLAQQEESARRYGL
>CP032698.1|AYG81206.1|3741192_3742344_+|putative-inactive-lipase
MHVRTRVAGAIAAALLLSAATPTAFADAPATTAPGDLVTQSPTEFHPLPGQWTNTKAWHITYRSTTAKGGPNVVSGTVIVPNDGRTGPRPVVTYAVGTVGLDDSCAPSANFPYGTAVEATLINQVVQKGWAVAVTDYEGLGTPGEHTYTVGRAEGTAVLDAARAAERLGIPGVDANSPVGIMGYSQGGQAASWAAELHDSYAPDLLVKGTATGGVPADLMKVASSNDGGLGSGLIFMAAAGQNAAFPELKLDSYLNTAGKALVGYFRTNCVAIDTTVGSFKHITDLTVKDPLRQPDWQARLAESKLGTHRPDAPVYLYHGTIDELIPYSVGQQLRSDWCARDANVEWHALPLLGHIGGVTAGGVPAANWLAERFAGAAPHPNC
>CP032698.1|AYG81205.1|3739986_3740994_+|putative-HTH-type-transcriptional-regulator
MAKPTITVHHVRAVLRGAGRRGIDTVPLLQASGIPPLLLGDDRARVTPAQFAHLFRALYRATGDEFLGLGGAPSRPGTFAMMCYAVLGCRDLGGAMRRGTAFYGLFADGPDLGLEVTGTEAVFAVRGDLGGHDEDRFLTECLVIIWHRLCSWLVGRRIPLTRAAFGYPPPPHQEEYESLFGCPVRFGGPRTEAVFDARWLTAPLVRDEAALGQMLRRSPFELLSRHAYGTTVGEQVGRALAGALRASPRLPSLEETAARLAMSPATLRRRLAHEGTSFQQLKDAVRRDAAIAGLAEGREPIAEIAARLGFSEDTSFHRAFRRWTGTTPGAYRLGR
>CP032698.1|AYG81204.1|3738089_3739766_-|Long-chain-fatty-acid--CoA-ligase-FadD15
MFTEWAAGRHPDRPALRFRDARGEWVSVTYAELRDTVRRTARGLLALGVEAGDRVVILAETRPEWMYAHFACLAVGAVVVPVYPTAGDEEALWVLSDSAARTVICEGPEEAARVEGLRGKLPALAHVLVMVGPAGPTMPDGSAVPLDDLLARADAVRPDDDAELVYTSGTTGPPKGCRLTHGNMGAVQDATLHLVEGGPGDRTYLYLPLAHLLAQLIQFSTLLYGGELCYFGGRIEDVVGELAEARPTHLPSVPRLFEKVYSVVRSLAEAQEGGGERFDAAVADGVLAADGALPPERQEAYEAADAALFGPVRAALGGRLRWALTGGAPIDPAVLDFLRACGIQVFEGYGMTESAGVISLNHPGAVRYGTVGRPVAGCEVRIADDGEVLARGPMIFPGYHANALGTAEALDADGWLHTGDLGSLDADGYLTITGRKKDLIITSAGKNLTPSHVELAIERSRFVSHAVMVGDRRPYPVALITVDAEETAGRDPAEVRALVQEAVETANAQVSRPARIRDFAILPGDFTVEGGELTPTLKVRRTAVVERYAAEIEALYHR
>CP032698.1|AYG81203.1|3737772_3737976_+|Cold-shock-like-protein-7.0
MATGTVKWFNAEKGFGFIAQDGGGPDVFVHYSAINASGFRSLEENQVVNFDVTQGPKGPQAENVTPA
>CP032698.1|AYG81202.1|3736598_3737465_-|Chorismate-dehydratase
MDNSTSPQHRGGRPRVGHIQFLNCLPLYWGLARTGTLLDLELTKDSPEKLSEQLVNGDLDIAPITLVEFLRNADDLVAFPDIAVGCDGPVMSCVIVSQRPLEELDGARVALGSTSRTSVRLAQLLLAERYRVTPDYYTCPPDLGLMMREADAAVLIGDAALRASLHDAPRLGLQVHDLGAMWKEWTGLPFVFAVWAARKDYLAREPDLVQQVHEAFLASRDLSLEEVTKVAEQAARWEVFDAELLERYFTTLDFRFGPQQLEGVREFARRTGPTTGFATDVNVELLAP
>CP032698.1|AYG81201.1|3735420_3736533_+|hypothetical-protein
MNRRRPAAWIAAAVIGSVVLVTGCSDEGKPVSFDSGPSSPSAQASAQGGAGDGGASGKDAKDGKDGKDAKDGKDDDASAQNGASPQTLLPTGPKAEFTTQSSLGDGTKIGVTTLKGAKSGFTGKVWVWAPKQYFEDKYKNSGFPVLIALPGGNGYPKNYWMGTDLKLQSSIAEWSRTGKSLPFIVVMPVLNPDAKYYYDGSDIPGRPKMGTWMTEDVPDLVRANFRTFSSRDGWAFMGSSSGGFVGLKSVLKRPDLFKAAIASGPDIVPDSPLWAGHDAEKQANNPEKLAQDLIDRKGPEVALAFQVGTKEGTVVPKVRSFIDTYGKGPVKTRLQLIQGGTHNAHTYVKGMGEGTMEWISKQMLAPIPSS
>CP032698.1|AYG81200.1|3732991_3735190_-|Serine/threonine-protein-kinase-AfsK
MQSLQPLEAGEPRTIGAYRLLGRLGAGGMGRVYLGRSAGGRTVAVKVVHPHFALDEQFRARFRHEVEAARRVGGRWTAPVLDADPDAPVPWVATGYVAGPSLTQAVLDRGPLPERSVRVLGAGLAEALAAVHALGLVHRDVKPSNVLLTLDGPRLIDFGIARATEGTASLTATGVSIGSPGYMAPEQILSRQVTGAADVFSLGAVLAYAATGRPPFPGDSSAALLYKVVHESAELGAGLTGELRDVVAGCLAKDPAARPSPTALAARLAPAGAAALVGEGWLPGPLVEEVSRSAVRLLDLEPEEPATGSGPIPFTSPAIGGSAERAGPGGPAVGGSPTAGVFGPPGASCDRDPDPPGNLRDPDPIPPYGREPGPSENRHASDPFPYGREPDRPENGREPGPSGVLREPGPFSYGRDPGSPGDLREPGSFSYGHASDPPGNLHEPGPIPYGREPGPSENRHASDPLPYGREPDRPENGREPGPFPGPRAPTGPRTPPDPRTRPGGAGLQAPSTPPRPTAPPSNAERHSRVALSVATAAEPGERGRGRRVSCTVVLAVAGALAGVTVGGAFLAGLLPNGGGDADHTSARPPASSGTASTPPGTPGSGQPGTGPQLGSVPSELVGTWKGVLTQDNGTSGYAYTAVITKGAKGTDVVRTTTTLGPLVCHGIGTLDSATARVLHITERTDPANPGTIGCTGGTATMTYTLQPDGTLRFESQEAEAGRPTGVLGKQGG
>CP032698.1|AYG81199.1|3731384_3732458_-|hypothetical-protein
MTFRGMTTEKARRLAAALDVADGALSIQGPLVSGILAKWEGDQGNLKRITQDASWSRDQAKDVRNRLGILEADPAVELMFMGMTGVLQTWKEFQEHKGEVGQYVDEFKEIKRNVTTPLRLTKIASGIEASLQLYQRWAQGQNVAGAKAVLELNKYFGITGDRLKLKNIDYMRELLKLQKIEGLYQEPWKWQQGLRAFLTTKLKIPLPPTLLAQGPGLSLLDRVGLPLAIVHGVKEMVVPDHKGVLGGFDRGMGVVEAGGAAAVLGGSAAAGALGASAAVAAAVPVVGWAALGVAGAYFIGTWAWDNRESIKNGAKKAWNATSKWAGSVADKGREIADGAKSAVTNLVPNAVKKFKFW
>CP032698.1|AYG81209.1|3743963_3745154_-|hypothetical-protein
MSQRRPAARLAALDGLRLVAALMVVGYHYLALSSAWGHSTATIFPTLHPFAQFGWLGVEVFFLVSGFVICMSVWGRTIGDFAVSRVSRLFPAYWVAIPLTALVVKKWPEISSIRHWDDVIVNFTMLQAGNGTKDVDGAYWTLFVEIKFYILMAIVVLCGVTYRNVLVFCGVWTVAAALAPGLGTPMLVAFAMPQYAPFFIAGIAFYLMRRYGANPVLWGLVLFQFLLAQRYIRYRMASNLGRAAAENLPTWPVRLIILAGFLMVGAIALGVFNKVQWKWLSTAGALTYPLYLIHMFIGLTLIHHFRGRVAAPVLVVSVVALMMAIAWLIHRFVERPASRWIRDSLKRGIADVRDNTPVARRRRVVPGAQPSAPAVAPAEFEPGVPVYLGSEQRRVH
>CP032698.1|AYG81210.1|3745538_3746216_-|HTH-type-transcriptional-repressor
MGEGVDDGVGDGKARRMPRAVRERQMLDAAVVTFGRRGYRAASMDEIAELAGVSKPLVYLYLNSKEDLFTACIRREAQALVTAVRSGVDPDLTADGQLWSGLRAFFTHTAEHPDAWSVLHHQARTHGEPFAREVSQMREEIVAFVTALIHEAAQEAHGATELAERDVAGLAQALVGAAESLAGWANASDSVTAKEAAATLMNFAWAGLGNLMRGERWSPRHQPAH
>CP032698.1|AYG81211.1|3746626_3747199_-|hypothetical-protein
MRTLISTAFISLDGVVEAPGGEAGYRNAGWTFKDIEFLPEAFALKGAEQKEATAMLLGRTSYEAFSPVWPDMADFADYKAMPKYVVSTTLTEDALVSNWGETTILRSVEDVAALKETEGGPIIVHGSATLNHALSDAGLIDRYHLLVFPLLLGAGKRLFSTTDKDKQRLKLVAHETYANGLQKNVFDVVH
>CP032698.1|AYG81212.1|3747569_3748943_-|C4-dicarboxylate-transport-protein
MSSASSATSASSATDQEKQPKSGFSISSKFPFWAQIIAGLVLGGLLGWLARSQDIGWLKETLGQIGDIFVQLLKLAVAPLVFFAILVSITNLRKVNNAARLATRTLLWFMITSLIAVAIGLAIGLLTDPGSGTGLTPKDGKLPKHTGSWLDFLTGIIPTDVVTPFTELNVLQIVFMAAVAGIALLQLGEKAKPILTLSEAVLELLQKALWWVIRLAPLGTLGLIGFAIADYGWDLIGKYATFTADVYIGCALVMFGVYPVLLATVAKVNPLQFFKGAWPAIQLAFVSRSSVGTMPLTQKVTERLGVPKEYASFAVPFGSTTKMDGCAAIYPALAAIFIAQIFDVHLGFDDYVLIAFVSVIGSAATAGLTGATVMLTLTLSTLGLPLEGVGLLMAIDPVLDMMRTATNVAGQALVPVIVSAREKILDRDAFDSVHLSPVDDTYESRTREDQSPVPAAA
>CP032698.1|AYG81213.1|3749329_3749626_-|hypothetical-protein
MNAAKPSATIWYTMLRVGIFIGSLVFVGLLVQFGIVPKGNGNSNLIWVVLLALVISAPLSYVLLRKQRDAMSAQIVTKVERAKAKLEANRTQEDGVTQ
>CP032698.1|AYG81214.1|3749685_3750228_-|hypothetical-protein
MALTFRLDPPVTPALRDGLLALWAGVSNAGGAVGFVPPVSVEDVRPELVKHLAAMAEGRMRLLVGFDERGAVAASAFIAFNTHRLMTHWVWLYTVMVDPVHQGKGYGRDLMTAVADAVRGLDGPGGSGRIEAIRLTCRGGTGVDRFYASCGYKEVGRVPGAIRVAEGDDRDDIIMLLPLN
>CP032698.1|AYG81215.1|3750237_3751401_-|Aminodeoxyfutalosine-synthase
MDAGLKRELEQKVRAGERLSREDGVALYASDDLAWLGGLAHEVRTRKNGDVVHFNVNRHLNMTNVCTASCAYCSFQRKPGEKDAYTMRIEEAVRLAKAMENESLTELHIVNGLHPTLPWRYYPRSLKALKEALPNVGLKAFTATEIHHFETISGLTASEILDELIEAGLESLTGGGAEIFDWEVRQHIVDHRTHWEDWSRIHRLAHEKGLKTPATMLYGHIEEPRHRVDHVLRLRELQDETGGFQVFIPLRYQHDFVDVQDGKVRNKLQARTTMATGAEALKTFAVSRLLFDNVPHVKCFWVMHGLQTTQLALQHGADDMDGSVVEYKITHDADNYGTPNKLTRDDLLDLIREAGFRPVERNTRYEIIREYPGPDASLREAPQPMRF
>CP032698.1|AYG81216.1|3751456_3751906_-|HTH-type-transcriptional-regulator-LrpC
MDAVDRQLIQALRENGRASYAELGRLVGLSGPSVTDRINRLEAAGVITGYRATVDAASLGLGVTALIGISLSDAADHEDVARRLRDLAEIEDCWFIAGDDSYMLKIRAGDVDGLEKTIRRLGSTKGVSRTRTTIVLSTKWENRVGELPE
>CP032698.1|AYG81217.1|3752048_3752171_+|hypothetical-protein
MYTIEMAYARMRELQDLANRSRAQQPSAKLRAPKRAAKKR
>CP032698.1|AYG81218.1|3752167_3752890_-|Flavin-prenyltransferase-UbiX
MEHVNVHSQQRTPWIVGVSGASGTPYAAAVLRALLAAGESVDLVVSRASRLTLLDETGIAFRDAHWQDDLRAWLARGADGKPDSFGACDVSDVRHWAPGDLAAGPSSGSYPVKGMLIVPASTACVAGVALGLSKDLLQRAASVTLKERRKLVVAVRETPLNGQTLGHLVTLDEAGAVVLPASPAFYAGATHIQDLVDFVAGRVLDAAGVPHGLYRRWEGELGSGRPRRAEPGPRGGSGGD

Crispr_ID: CP032698_27

• CRISPR_ID: CP032698_27
• CRISPR_location: 3746412-3746608
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP032698_27

Consensus_repeat	Method
NCGCGCAGTTCCCCGCGCCCCTGAA	CRT
CCGTGCGGGGCCGGGC----------------GCGCAGTTCCCCGCGCCCCTGAA	PILER-CR

spacers of CP032698_27

>27.1|3746436|35|CP032698|CRT
AACCCGCCTTCGTCCGCGGACCGTGCGGGGCCGGG
>27.2|3746495|31|CP032698|CRT
CCCCGTCGACCGTGCGGTCCCTGGCCGCTTC
>27.3|3746550|35|CP032698|CRT
AACCCGCCTTCGTCCGCGGGCCGTGCGTGGCTGGG
>27.4|3746495|42|CP032698|PILER-CR
TAACCCCGTCGACCGTGCGGTCCCTGGCCGCTTCTCGCGCAG
>27.5|3746576|20|CP032698|PILER-CR
AACCCGCCTTCGTCCGCGGG

CRISPR arrays and Neighbor proteins around CP032698_27

CRISPR arrays

The CRISPR arrays of CP032698_27

>merge|CP032698|27|3746412-3746608|CRT,PILER-CR
CGCGCAGTTCCTCGCGCCCCTGGAAACCCGCCTTCGTCCGCGGACCGTGCGGGGCCGGGCGCGCAGTTCCCCGCGCCCCTTAACCCCGTCGACCGTGCGGTCCCTGGCCGCTTCTCGCGCAGTCCCCGCGCCCCTGAAAACCCGCCTTCGTCCGCGGGCCGTGCGTGGCTGGGCGCGCAGTTCCCCGCGCCCCTGAA

>CP032698|27|2|3746412-3746608|CRT
CGCGCAGTTCCTCGCGCCCCTGGA	AACCCGCCTTCGTCCGCGGACCGTGCGGGGCCGGG
CGCGCAGTTCCCCGCGCCCCTTAA	CCCCGTCGACCGTGCGGTCCCTGGCCGCTTC
TCGCGCAGTCCCCGCGCCCCTGAA	AACCCGCCTTCGTCCGCGGGCCGTGCGTGGCTGGG
CGCGCAGTTCCCCGCGCCCCTGAA

>CP032698|27|8|3746456-3746608|PILER-CR
CCGTGCGGGGCCGGGCGCGCAGTTCCCCGCGCCCCTTAA	CCCCGTCGACCGTGCGGTCCCTGGCCGCTTCTCGCGCAGTCC
CCGCGCCCCTGAAAACCCGCCTTCGTCCGCGGGCCGTGC	GTGGCTGGGCGCGCAGTTCC
CCGCGCCCCTGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81203.1|3737772_3737976_+|Cold-shock-like-protein-7.0	unknown	unknown	gnl|CDD|224197
CP032698.1|AYG81202.1|3736598_3737465_-|Chorismate-dehydratase	unknown	unknown	gnl|CDD|270352
CP032698.1|AYG81216.1|3751456_3751906_-|HTH-type-transcriptional-regulator-LrpC	unknown	unknown	gnl|CDD|214628
CP032698.1|AYG81211.1|3746626_3747199_-|hypothetical-protein	unknown	unknown	gnl|CDD|334719
CP032698.1|AYG81217.1|3752048_3752171_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81205.1|3739986_3740994_+|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|378890
CP032698.1|AYG81206.1|3741192_3742344_+|putative-inactive-lipase	unknown	unknown	gnl|CDD|367570
CP032698.1|AYG81218.1|3752167_3752890_-|Flavin-prenyltransferase-UbiX	unknown	unknown	gnl|CDD|223241
CP032698.1|AYG81204.1|3738089_3739766_-|Long-chain-fatty-acid--CoA-ligase-FadD15	unknown	unknown	gnl|CDD|341233
CP032698.1|AYG81212.1|3747569_3748943_-|C4-dicarboxylate-transport-protein	unknown	unknown	gnl|CDD|366058
CP032698.1|AYG81208.1|3743147_3743645_+|hypothetical-protein	unknown	unknown	gnl|CDD|316352
CP032698.1|AYG81201.1|3735420_3736533_+|hypothetical-protein	unknown	unknown	gnl|CDD|366286
CP032698.1|AYG81207.1|3742366_3743008_-|hypothetical-protein	unknown	unknown	gnl|CDD|133407
CP032698.1|AYG81214.1|3749685_3750228_-|hypothetical-protein	unknown	unknown	gnl|CDD|366181
CP032698.1|AYG81210.1|3745538_3746216_-|HTH-type-transcriptional-repressor	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG81220.1|3753916_3755374_-|3-octaprenyl-4-hydroxybenzoate-carboxy-lyase	unknown	unknown	gnl|CDD|163413
CP032698.1|AYG81213.1|3749329_3749626_-|hypothetical-protein	unknown	unknown	gnl|CDD|379415
CP032698.1|AYG81209.1|3743963_3745154_-|hypothetical-protein	unknown	unknown	gnl|CDD|224748
CP032698.1|AYG81215.1|3750237_3751401_-|Aminodeoxyfutalosine-synthase	unknown	unknown	gnl|CDD|213851
CP032698.1|AYG81219.1|3752937_3753819_-|4-hydroxybenzoate-solanesyltransferase	unknown	unknown	gnl|CDD|183814

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81203.1|3737772_3737976_+|Cold-shock-like-protein-7.0	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.38642e-36
CP032698.1|AYG81202.1|3736598_3737465_-|Chorismate-dehydratase	gnl|CDD|270352	cd13634, PBP2_Sco4506, The conserved hypothetical protein SCO4506 exhibits the type 2 periplasmic-binidng protein fold. This group includes the SCO4506 protein from Streptomyces coelicolor and related hypothetical proteins. SCO4506 is an ortholog of Ttha1568 (MqnD) from Thermus thermophilies HB8. MqnD is an enzyme within an alternative menaquinone biosynthetic pathway that catalyzes the conversion of cyclic de-hypoxanthine futalosine to 1,4-dihydroxy-6-naphthoate. Menaquinone (MK; vitamin K) is an essential lipid-soluble carrier that shuttles electrons between membrane-bound protein complexes in the electron transport chain. SCO4506 has significant structural homology with the members of type 2 periplasmic-binding fold protein superfamily. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.51054e-112
CP032698.1|AYG81216.1|3751456_3751906_-|HTH-type-transcriptional-regulator-LrpC	gnl|CDD|214628	smart00344, HTH_ASNC, helix_turn_helix ASNC type. AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli).	5.23492e-35
CP032698.1|AYG81211.1|3746626_3747199_-|hypothetical-protein	gnl|CDD|334719	pfam01872, RibD_C, RibD C-terminal domain. The function of this domain is not known, but it is thought to be involved in riboflavin biosynthesis. This domain is found in the C-terminus of RibD/RibG, in combination with pfam00383, as well as in isolation in some archaebacterial proteins. This family appears to be related to pfam00186.	7.95447e-32
CP032698.1|AYG81205.1|3739986_3740994_+|putative-HTH-type-transcriptional-regulator	gnl|CDD|378890	pfam12625, Arabinose_bd, Arabinose-binding domain of AraC transcription regulator, N-term. AraC is a bacterial transcriptional regulatory protein with a DNA-binding domain at the C-terminus, HTH_AraC, pfam00165, and this dimerization domain which harbours the arabinose-binding pocket at the N-terminus. AraC positively and negatively regulates expression of the proteins required for the uptake and catabolism of the sugar L-arabinose 1,2,3].	1.46484e-46
CP032698.1|AYG81206.1|3741192_3742344_+|putative-inactive-lipase	gnl|CDD|367570	pfam03583, LIP, Secretory lipase. These lipases are expressed and secreted during the infection cycle of these pathogens. In particular, C. albicans has a large number of different lipases, possibly reflecting broad lipolytic activity, which may contribute to the persistence and virulence of C. albicans in human tissue.	1.24112e-48
CP032698.1|AYG81218.1|3752167_3752890_-|Flavin-prenyltransferase-UbiX	gnl|CDD|223241	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism].	1.51033e-65
CP032698.1|AYG81204.1|3738089_3739766_-|Long-chain-fatty-acid--CoA-ligase-FadD15	gnl|CDD|341233	cd05907, VL_LC_FACS_like, Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases. This family includes long-chain fatty acid (C12-C20) CoA synthetases and Bubblegum-like very long-chain (>C20) fatty acid CoA synthetases. FACS catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, and the formation of a fatty acyl-CoA. Eukaryotes generally have multiple isoforms of LC-FACS genes with multiple splice variants. For example, nine genes are found in Arabidopsis and six genes are expressed in mammalian cells. Drosophila melanogaster mutant bubblegum (BGM) have elevated levels of very-long-chain fatty acids (VLCFA) caused by a defective gene later named bubblegum. The human homolog (hsBG) of bubblegum has been characterized as a very long chain fatty acid CoA synthetase that functions specifically in the brain; hsBG may play a central role in brain VLCFA metabolism and myelinogenesis. Free fatty acids must be "activated" to their CoA thioesters before participating in most catabolic and anabolic reactions.	1.91268e-174
CP032698.1|AYG81212.1|3747569_3748943_-|C4-dicarboxylate-transport-protein	gnl|CDD|366058	pfam00375, SDF, Sodium:dicarboxylate symporter family.	1.66256e-114
CP032698.1|AYG81208.1|3743147_3743645_+|hypothetical-protein	gnl|CDD|316352	pfam13826, DUF4188, Domain of unknown function (DUF4188).	8.2867e-52
CP032698.1|AYG81201.1|3735420_3736533_+|hypothetical-protein	gnl|CDD|366286	pfam00756, Esterase, Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family.	4.92568e-11
CP032698.1|AYG81207.1|3742366_3743008_-|hypothetical-protein	gnl|CDD|133407	cd04780, HTH_MerR-like_sg5, Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily. Putative helix-turn-helix (HTH) MerR-like transcription regulators (subgroup 5), N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	1.32022e-27
CP032698.1|AYG81214.1|3749685_3750228_-|hypothetical-protein	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.30789e-06
CP032698.1|AYG81210.1|3745538_3746216_-|HTH-type-transcriptional-repressor	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.27915e-14
CP032698.1|AYG81220.1|3753916_3755374_-|3-octaprenyl-4-hydroxybenzoate-carboxy-lyase	gnl|CDD|163413	TIGR03701, mena_SCO4490, menaquinone biosynthesis decarboxylase, SCO4490 family. Members of this protein family are putative decarboxylases involved in a late stage of the alternative pathway for menaquinone, via futalosine, as in Streptomyces coelicolor and Helicobacter pylori. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	0
CP032698.1|AYG81213.1|3749329_3749626_-|hypothetical-protein	gnl|CDD|379415	pfam14012, DUF4229, Protein of unknown function (DUF4229). This family of integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 95 and 122 amino acids in length.	5.13663e-14
CP032698.1|AYG81209.1|3743963_3745154_-|hypothetical-protein	gnl|CDD|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	1.74655e-27
CP032698.1|AYG81215.1|3750237_3751401_-|Aminodeoxyfutalosine-synthase	gnl|CDD|213851	TIGR03700, mena_SCO4494, putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family. Members of this protein family appear to be involved in menaquinone biosynthesis by an alternate pathway via futalosine, based on close phylogenetic correlation with known markers of the futalosine pathway, gene clustering in many organisms, and paralogy with the SCO4550 protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	0
CP032698.1|AYG81219.1|3752937_3753819_-|4-hydroxybenzoate-solanesyltransferase	gnl|CDD|183814	PRK12888, ubiA, 4-hydroxybenzoate octaprenyltransferase.	9.57538e-171

Protein sequences

>CP032698.1|AYG81210.1|3745538_3746216_-|HTH-type-transcriptional-repressor
MGEGVDDGVGDGKARRMPRAVRERQMLDAAVVTFGRRGYRAASMDEIAELAGVSKPLVYLYLNSKEDLFTACIRREAQALVTAVRSGVDPDLTADGQLWSGLRAFFTHTAEHPDAWSVLHHQARTHGEPFAREVSQMREEIVAFVTALIHEAAQEAHGATELAERDVAGLAQALVGAAESLAGWANASDSVTAKEAAATLMNFAWAGLGNLMRGERWSPRHQPAH
>CP032698.1|AYG81209.1|3743963_3745154_-|hypothetical-protein
MSQRRPAARLAALDGLRLVAALMVVGYHYLALSSAWGHSTATIFPTLHPFAQFGWLGVEVFFLVSGFVICMSVWGRTIGDFAVSRVSRLFPAYWVAIPLTALVVKKWPEISSIRHWDDVIVNFTMLQAGNGTKDVDGAYWTLFVEIKFYILMAIVVLCGVTYRNVLVFCGVWTVAAALAPGLGTPMLVAFAMPQYAPFFIAGIAFYLMRRYGANPVLWGLVLFQFLLAQRYIRYRMASNLGRAAAENLPTWPVRLIILAGFLMVGAIALGVFNKVQWKWLSTAGALTYPLYLIHMFIGLTLIHHFRGRVAAPVLVVSVVALMMAIAWLIHRFVERPASRWIRDSLKRGIADVRDNTPVARRRRVVPGAQPSAPAVAPAEFEPGVPVYLGSEQRRVH
>CP032698.1|AYG81208.1|3743147_3743645_+|hypothetical-protein
MSAKQAPNRTTAAAEGEVVVLLIGMRVNHFWAVHQWVPVGFAMLRMLAELKRDRSRGLLGHVLLTASPRTYYVVQYWESKEKLYAYAHSPQMFHHRAWAILNRKERQGKVRGHVGLWHETYVVPEGSYESIYADMPPFGLAAATGVLPLARRGRTAADRLAHRPA
>CP032698.1|AYG81207.1|3742366_3743008_-|hypothetical-protein
MRLAELSERSGVSAAMIKYYLRQGMLAPGRKVGATTADYDESHLRRLRLVRALIEVGGLTVARAKEVIGYVDDDSLDRTIRLGAALWALPHGPDPDDGDASVAVARVEVDRLLDALGWTTARELGELSPDHRALIVAVATLHRLGYSWDAEFMAPYAELMHRAAVRDLDFVETHPSEEEKVEVAVAATVLFDPVLRALHRLAQQEESARRYGL
>CP032698.1|AYG81206.1|3741192_3742344_+|putative-inactive-lipase
MHVRTRVAGAIAAALLLSAATPTAFADAPATTAPGDLVTQSPTEFHPLPGQWTNTKAWHITYRSTTAKGGPNVVSGTVIVPNDGRTGPRPVVTYAVGTVGLDDSCAPSANFPYGTAVEATLINQVVQKGWAVAVTDYEGLGTPGEHTYTVGRAEGTAVLDAARAAERLGIPGVDANSPVGIMGYSQGGQAASWAAELHDSYAPDLLVKGTATGGVPADLMKVASSNDGGLGSGLIFMAAAGQNAAFPELKLDSYLNTAGKALVGYFRTNCVAIDTTVGSFKHITDLTVKDPLRQPDWQARLAESKLGTHRPDAPVYLYHGTIDELIPYSVGQQLRSDWCARDANVEWHALPLLGHIGGVTAGGVPAANWLAERFAGAAPHPNC
>CP032698.1|AYG81205.1|3739986_3740994_+|putative-HTH-type-transcriptional-regulator
MAKPTITVHHVRAVLRGAGRRGIDTVPLLQASGIPPLLLGDDRARVTPAQFAHLFRALYRATGDEFLGLGGAPSRPGTFAMMCYAVLGCRDLGGAMRRGTAFYGLFADGPDLGLEVTGTEAVFAVRGDLGGHDEDRFLTECLVIIWHRLCSWLVGRRIPLTRAAFGYPPPPHQEEYESLFGCPVRFGGPRTEAVFDARWLTAPLVRDEAALGQMLRRSPFELLSRHAYGTTVGEQVGRALAGALRASPRLPSLEETAARLAMSPATLRRRLAHEGTSFQQLKDAVRRDAAIAGLAEGREPIAEIAARLGFSEDTSFHRAFRRWTGTTPGAYRLGR
>CP032698.1|AYG81204.1|3738089_3739766_-|Long-chain-fatty-acid--CoA-ligase-FadD15
MFTEWAAGRHPDRPALRFRDARGEWVSVTYAELRDTVRRTARGLLALGVEAGDRVVILAETRPEWMYAHFACLAVGAVVVPVYPTAGDEEALWVLSDSAARTVICEGPEEAARVEGLRGKLPALAHVLVMVGPAGPTMPDGSAVPLDDLLARADAVRPDDDAELVYTSGTTGPPKGCRLTHGNMGAVQDATLHLVEGGPGDRTYLYLPLAHLLAQLIQFSTLLYGGELCYFGGRIEDVVGELAEARPTHLPSVPRLFEKVYSVVRSLAEAQEGGGERFDAAVADGVLAADGALPPERQEAYEAADAALFGPVRAALGGRLRWALTGGAPIDPAVLDFLRACGIQVFEGYGMTESAGVISLNHPGAVRYGTVGRPVAGCEVRIADDGEVLARGPMIFPGYHANALGTAEALDADGWLHTGDLGSLDADGYLTITGRKKDLIITSAGKNLTPSHVELAIERSRFVSHAVMVGDRRPYPVALITVDAEETAGRDPAEVRALVQEAVETANAQVSRPARIRDFAILPGDFTVEGGELTPTLKVRRTAVVERYAAEIEALYHR
>CP032698.1|AYG81203.1|3737772_3737976_+|Cold-shock-like-protein-7.0
MATGTVKWFNAEKGFGFIAQDGGGPDVFVHYSAINASGFRSLEENQVVNFDVTQGPKGPQAENVTPA
>CP032698.1|AYG81202.1|3736598_3737465_-|Chorismate-dehydratase
MDNSTSPQHRGGRPRVGHIQFLNCLPLYWGLARTGTLLDLELTKDSPEKLSEQLVNGDLDIAPITLVEFLRNADDLVAFPDIAVGCDGPVMSCVIVSQRPLEELDGARVALGSTSRTSVRLAQLLLAERYRVTPDYYTCPPDLGLMMREADAAVLIGDAALRASLHDAPRLGLQVHDLGAMWKEWTGLPFVFAVWAARKDYLAREPDLVQQVHEAFLASRDLSLEEVTKVAEQAARWEVFDAELLERYFTTLDFRFGPQQLEGVREFARRTGPTTGFATDVNVELLAP
>CP032698.1|AYG81201.1|3735420_3736533_+|hypothetical-protein
MNRRRPAAWIAAAVIGSVVLVTGCSDEGKPVSFDSGPSSPSAQASAQGGAGDGGASGKDAKDGKDGKDAKDGKDDDASAQNGASPQTLLPTGPKAEFTTQSSLGDGTKIGVTTLKGAKSGFTGKVWVWAPKQYFEDKYKNSGFPVLIALPGGNGYPKNYWMGTDLKLQSSIAEWSRTGKSLPFIVVMPVLNPDAKYYYDGSDIPGRPKMGTWMTEDVPDLVRANFRTFSSRDGWAFMGSSSGGFVGLKSVLKRPDLFKAAIASGPDIVPDSPLWAGHDAEKQANNPEKLAQDLIDRKGPEVALAFQVGTKEGTVVPKVRSFIDTYGKGPVKTRLQLIQGGTHNAHTYVKGMGEGTMEWISKQMLAPIPSS
>CP032698.1|AYG81211.1|3746626_3747199_-|hypothetical-protein
MRTLISTAFISLDGVVEAPGGEAGYRNAGWTFKDIEFLPEAFALKGAEQKEATAMLLGRTSYEAFSPVWPDMADFADYKAMPKYVVSTTLTEDALVSNWGETTILRSVEDVAALKETEGGPIIVHGSATLNHALSDAGLIDRYHLLVFPLLLGAGKRLFSTTDKDKQRLKLVAHETYANGLQKNVFDVVH
>CP032698.1|AYG81212.1|3747569_3748943_-|C4-dicarboxylate-transport-protein
MSSASSATSASSATDQEKQPKSGFSISSKFPFWAQIIAGLVLGGLLGWLARSQDIGWLKETLGQIGDIFVQLLKLAVAPLVFFAILVSITNLRKVNNAARLATRTLLWFMITSLIAVAIGLAIGLLTDPGSGTGLTPKDGKLPKHTGSWLDFLTGIIPTDVVTPFTELNVLQIVFMAAVAGIALLQLGEKAKPILTLSEAVLELLQKALWWVIRLAPLGTLGLIGFAIADYGWDLIGKYATFTADVYIGCALVMFGVYPVLLATVAKVNPLQFFKGAWPAIQLAFVSRSSVGTMPLTQKVTERLGVPKEYASFAVPFGSTTKMDGCAAIYPALAAIFIAQIFDVHLGFDDYVLIAFVSVIGSAATAGLTGATVMLTLTLSTLGLPLEGVGLLMAIDPVLDMMRTATNVAGQALVPVIVSAREKILDRDAFDSVHLSPVDDTYESRTREDQSPVPAAA
>CP032698.1|AYG81213.1|3749329_3749626_-|hypothetical-protein
MNAAKPSATIWYTMLRVGIFIGSLVFVGLLVQFGIVPKGNGNSNLIWVVLLALVISAPLSYVLLRKQRDAMSAQIVTKVERAKAKLEANRTQEDGVTQ
>CP032698.1|AYG81214.1|3749685_3750228_-|hypothetical-protein
MALTFRLDPPVTPALRDGLLALWAGVSNAGGAVGFVPPVSVEDVRPELVKHLAAMAEGRMRLLVGFDERGAVAASAFIAFNTHRLMTHWVWLYTVMVDPVHQGKGYGRDLMTAVADAVRGLDGPGGSGRIEAIRLTCRGGTGVDRFYASCGYKEVGRVPGAIRVAEGDDRDDIIMLLPLN
>CP032698.1|AYG81215.1|3750237_3751401_-|Aminodeoxyfutalosine-synthase
MDAGLKRELEQKVRAGERLSREDGVALYASDDLAWLGGLAHEVRTRKNGDVVHFNVNRHLNMTNVCTASCAYCSFQRKPGEKDAYTMRIEEAVRLAKAMENESLTELHIVNGLHPTLPWRYYPRSLKALKEALPNVGLKAFTATEIHHFETISGLTASEILDELIEAGLESLTGGGAEIFDWEVRQHIVDHRTHWEDWSRIHRLAHEKGLKTPATMLYGHIEEPRHRVDHVLRLRELQDETGGFQVFIPLRYQHDFVDVQDGKVRNKLQARTTMATGAEALKTFAVSRLLFDNVPHVKCFWVMHGLQTTQLALQHGADDMDGSVVEYKITHDADNYGTPNKLTRDDLLDLIREAGFRPVERNTRYEIIREYPGPDASLREAPQPMRF
>CP032698.1|AYG81216.1|3751456_3751906_-|HTH-type-transcriptional-regulator-LrpC
MDAVDRQLIQALRENGRASYAELGRLVGLSGPSVTDRINRLEAAGVITGYRATVDAASLGLGVTALIGISLSDAADHEDVARRLRDLAEIEDCWFIAGDDSYMLKIRAGDVDGLEKTIRRLGSTKGVSRTRTTIVLSTKWENRVGELPE
>CP032698.1|AYG81217.1|3752048_3752171_+|hypothetical-protein
MYTIEMAYARMRELQDLANRSRAQQPSAKLRAPKRAAKKR
>CP032698.1|AYG81218.1|3752167_3752890_-|Flavin-prenyltransferase-UbiX
MEHVNVHSQQRTPWIVGVSGASGTPYAAAVLRALLAAGESVDLVVSRASRLTLLDETGIAFRDAHWQDDLRAWLARGADGKPDSFGACDVSDVRHWAPGDLAAGPSSGSYPVKGMLIVPASTACVAGVALGLSKDLLQRAASVTLKERRKLVVAVRETPLNGQTLGHLVTLDEAGAVVLPASPAFYAGATHIQDLVDFVAGRVLDAAGVPHGLYRRWEGELGSGRPRRAEPGPRGGSGGD
>CP032698.1|AYG81219.1|3752937_3753819_-|4-hydroxybenzoate-solanesyltransferase
MPQPGRTKAFLRLVMIEHSVFALPFAYTAALTAMYQLDKNIHWGRLLLVTVAMVGLRTFAMACNRIIDREIDARNPRTAGRELVTGAVSVRSAWTGALIALVVFLGAAAALNPLCLALAPVAVIPMVVYPYGKRFTNFPQAILGLAQAMGPVGAWIAITGSWSWDAVILGLAIGIWIGGFDLIYACQDVEADRGHGVKSVPARFGIPAAIYGARGCHSVTMALLVWYALATGAGFFFWLGLLIVLGAFLYEHTLVKPHDLSRLNRAFFQVNGFIGIALFVCALIDLLVRGLTV
>CP032698.1|AYG81220.1|3753916_3755374_-|3-octaprenyl-4-hydroxybenzoate-carboxy-lyase
MAYDDLRSLLRALEREGDLKRIKAEVDPYLEVGEIVDRVNKAGGPALLFENVKGASMPLAMNVYGTDRRLLKALGLTAYEEISEKIGGLLKPELPQGFVGIREAFGKLGSMVHVPPKKVKQEAAPVQEVVLTGDDVDLDMLPALFTWPEDGGSFFNLGLTHTKHPETGVRNLGLYRLQRHDKRTIGMHWQIHKDSRNHYAVAAKRGERLPVAIAFGCPPAVTYASTAPLPGDIDEYLFAGFIQGKRIEMVDCKTVPLQVPANAEVVIEGWLEPGEMLPEGPFGDHTGFYTPQEPFPALTIDCVTMRKRPLLQSIVVGRPPTEDGPLGRATERFFLPLLKIIVPDIVDYHLPESGGFHNCAIVSIDKKYPKHAQKVMHAIWGAHMMSLTKLIVIVDADCDVHNLHEVSWRAFGNTDYARDLTVVEGPVDHLDHASYQQFWGGKAGIDATAKWPEEGYTRDGGWPAMVESDPDTAERVTKRWKEYGL

Crispr_ID: CP032698_28

• CRISPR_ID: CP032698_28
• CRISPR_location: 3838853-3838951
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_28

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGG	CRISPRCasFinder

spacers of CP032698_28

>28.1|3838877|51|CP032698|CRISPRCasFinder
AGGCCCGGAACCATCCAACCCGCTGCACGGGCGGGTGGGTGGGAAAACGCC

CRISPR arrays and Neighbor proteins around CP032698_28

CRISPR arrays

The CRISPR arrays of CP032698_28

>merge|CP032698|28|3838853-3838951|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGAGGCCCGGAACCATCCAACCCGCTGCACGGGCGGGTGGGTGGGAAAACGCCCGGGGTCTGGGGCGGAGCCCCAGG

>CP032698|28|21|3838853-3838951|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGG	AGGCCCGGAACCATCCAACCCGCTGCACGGGCGGGTGGGTGGGAAAACGCC
CGGGGTCTGGGGCGGAGCCCCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81295.1|3841643_3842513_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81300.1|3847694_3848618_-|hypothetical-protein	unknown	unknown	gnl|CDD|164795
CP032698.1|AYG81289.1|3833804_3834203_-|hypothetical-protein	unknown	unknown	gnl|CDD|227324
CP032698.1|AYG81297.1|3844313_3845930_+|DNA-repair-protein-RadA	unknown	unknown	gnl|CDD|236994
CP032698.1|AYG81301.1|3848705_3849332_+|Undecaprenyl-diphosphatase-BcrC	unknown	unknown	gnl|CDD|239489
CP032698.1|AYG81291.1|3836560_3838411_-|Dihydroxy-acid-dehydratase	unknown	unknown	gnl|CDD|237104
CP032698.1|AYG81284.1|3828804_3829614_-|Pyrroline-5-carboxylate-reductase	unknown	unknown	gnl|CDD|237008
CP032698.1|AYG81283.1|3827725_3828547_+|hypothetical-protein	unknown	unknown	gnl|CDD|240291
CP032698.1|AYG81294.1|3840712_3841624_-|Exopolyphosphatase	unknown	unknown	gnl|CDD|223326
CP032698.1|AYG81285.1|3829746_3830484_-|Inner-membrane-transport-permease-YbhR	unknown	unknown	gnl|CDD|366444
CP032698.1|AYG81296.1|3842548_3844132_-|hypothetical-protein	unknown	unknown	gnl|CDD|274357
CP032698.1|AYG81282.1|3821303_3821948_-|6-phosphogluconate-phosphatase	unknown	unknown	gnl|CDD|319828
CP032698.1|AYG81299.1|3847485_3847698_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81286.1|3830597_3831323_-|Ribosome-associated-ATPase	unknown	unknown	gnl|CDD|224054
CP032698.1|AYG81290.1|3834360_3836529_+|Serine/threonine-protein-kinase-AfsK	unknown	unknown	gnl|CDD|270916
CP032698.1|AYG81292.1|3839009_3839729_-|HTH-type-transcriptional-regulator-BetI	unknown	unknown	gnl|CDD|380054
CP032698.1|AYG81287.1|3831949_3832702_-|putative-methyltransferase	unknown	unknown	gnl|CDD|369777
CP032698.1|AYG81298.1|3846031_3847156_+|DNA-integrity-scanning-protein-DisA	unknown	unknown	gnl|CDD|237395
CP032698.1|AYG81288.1|3833213_3833759_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81293.1|3839725_3840535_-|hypothetical-protein	unknown	unknown	gnl|CDD|224007

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81300.1|3847694_3848618_-|hypothetical-protein	gnl|CDD|164795	PHA00370, III, attachment protein.	3.28227e-06
CP032698.1|AYG81289.1|3833804_3834203_-|hypothetical-protein	gnl|CDD|227324	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown].	4.61181e-09
CP032698.1|AYG81297.1|3844313_3845930_+|DNA-repair-protein-RadA	gnl|CDD|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
CP032698.1|AYG81301.1|3848705_3849332_+|Undecaprenyl-diphosphatase-BcrC	gnl|CDD|239489	cd03395, PAP2_like_4, PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	1.02788e-21
CP032698.1|AYG81291.1|3836560_3838411_-|Dihydroxy-acid-dehydratase	gnl|CDD|237104	PRK12448, PRK12448, dihydroxy-acid dehydratase; Provisional.	0
CP032698.1|AYG81284.1|3828804_3829614_-|Pyrroline-5-carboxylate-reductase	gnl|CDD|237008	PRK11880, PRK11880, pyrroline-5-carboxylate reductase; Reviewed.	6.14134e-109
CP032698.1|AYG81283.1|3827725_3828547_+|hypothetical-protein	gnl|CDD|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.00341706
CP032698.1|AYG81294.1|3840712_3841624_-|Exopolyphosphatase	gnl|CDD|223326	COG0248, GppA, Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism].	3.12853e-78
CP032698.1|AYG81285.1|3829746_3830484_-|Inner-membrane-transport-permease-YbhR	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	1.85499e-23
CP032698.1|AYG81296.1|3842548_3844132_-|hypothetical-protein	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	2.27913e-09
CP032698.1|AYG81282.1|3821303_3821948_-|6-phosphogluconate-phosphatase	gnl|CDD|319828	cd07526, HAD_BPGM_like, subfamily of beta-phosphoglucomutase-like family, similar to Escherichia coli 6-phosphogluconate phosphatase YieH. This subfamily includes Escherichia coli YieH/HAD3 an 6-phosphogluconate phosphatase, which can hydrolyzed purines and pyrimidines as secondary substrates. It belongs to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), Saccharomyces cerevisiae phosphatases GPP1 and GPP2 that dephosphorylate DL-glycerol-3-phosphate, and DOG1 and DOG2 that dephosphorylate 2-deoxyglucose-6-phosphate. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.26721e-55
CP032698.1|AYG81286.1|3830597_3831323_-|Ribosome-associated-ATPase	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.78974e-77
CP032698.1|AYG81290.1|3834360_3836529_+|Serine/threonine-protein-kinase-AfsK	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	9.59814e-84
CP032698.1|AYG81292.1|3839009_3839729_-|HTH-type-transcriptional-regulator-BetI	gnl|CDD|380054	pfam17920, TetR_C_16, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. This entry represents the C-terminal domain found in a number of different TetR transcription regulator proteins found in Actinobacteria. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain.	3.47725e-32
CP032698.1|AYG81287.1|3831949_3832702_-|putative-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	5.30878e-19
CP032698.1|AYG81298.1|3846031_3847156_+|DNA-integrity-scanning-protein-DisA	gnl|CDD|237395	PRK13482, PRK13482, DNA integrity scanning protein DisA; Provisional.	0
CP032698.1|AYG81293.1|3839725_3840535_-|hypothetical-protein	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	8.21328e-28

Protein sequences

>CP032698.1|AYG81291.1|3836560_3838411_-|Dihydroxy-acid-dehydratase
MPELRSRTVTHGRNMAGARALMRASGVASEDIGKPIIAVANSFTEFVPGHTHLAPVGRIVSEAILAAGAVPREFNTIAVDDGIAMGHGGMLYSLPSRDLIADSVEYMVEAHCADALICISNCDKITPGMLMAALRLNIPTVFVSGGPMESGKATLVDGTVRTLDLVDAISDAVNDKISDADILRIEENACPTCGSCSGMFTANSMNCLTEAIGLSLPGNGSVLATHTARRALYENAARTVVEITKRHYEDDDHSVLPRSIATRAAFENAMALDIAMGGSTNTILHLLAAAQEAELDYGLSDMDAVSRRVPCLAKVAPNVAKDRTYYMEDVHRAGGIPAILGELYRAGLLNEDVHTVHSRSIKEWLDAWDVRGGSPSPEAVELWHAAPGCVRSATAFSQSERWDTLDTDAAEGCIRDAAHAYSKDGGLAVLRGNLAEDGCVVKTAGVDESIWTFEGPVVVCESQEDAVDKILRKEITHGDVVVIRYEGPKGGPGMQEMLYPTSFLKGRGLGKTCALITDGRFSGGTSGLSIGHASPEAASGGTIALVEDGDRIRIDIPNRSIELLVPEAELASRREALGGVYAPKNRERKVSAALRAYAAMATSADRGAVRDVSKLG
>CP032698.1|AYG81290.1|3834360_3836529_+|Serine/threonine-protein-kinase-AfsK
MASPRRIGFGAPGAEDPESVGSYRLESVIGSGGMGVVHLATSPSGMRLAVKVVHVQHAADPEFRARFRQEVSAARRVSGAFTASVVDADPDAERPWMATLHIPGPTLAERVKQTGPLPADEVRRLGAGLAEALRDIHRAGVVHRDLKPSNVLLAADGPKVIDFGISRPYDSDLRTETGKLIGTPPFMAPEQFQRPREVGPAADVFAMGAVLVHAATGRGPFDSESPYVVAYQVVHNEPDLAGVPDDLVPVLRGCLAKDPGERPTPDELMSALRSAAYGSEAQIPTQRFRNPVAVTPPPSSSGSGSRSGAAPGSDARAGSGPGRPRRLRWGIAALALVAVVGAAVVAVRAMPDGTGTQAEASERHDSPRFRPWEARLGAAAQQDGANRTAFCSAGSGGGALYCSAPGIALTRLDAVGGKVMWSVPGAGGQLLSDDYAPVVAGDRVLARAPGGPLRAYDPATGQPTWSADVSAYSAVRPVGATVLLVTADGHVTALNSLTGKERWRKAAGGPRSQWVTSEGGGGAMAYAVTPSADGGSTSVSAVDPADGSVRWRARVEGRLRPVAADAGAVVLLATDAAGFTSAVVRLDTATHTTRRTTLSAPLDQAQAGIDGDAVYLFGAGGALVAVDSAHGTEKWRLDTGVARASQPVAAGGQVFLTGADGRLLAFDAGKGVLAGQTNPRMHDGRYTFTPALPAPLTAGGRVYAASPDGSVFAVNPADIASW
>CP032698.1|AYG81289.1|3833804_3834203_-|hypothetical-protein
MGEYMGEMGMTAESAETATGASETAAPKTVMAAPETAMAASEMAMTASLGTHRYPVAPGCELNVRSGPGTGYSIVDVLPLGASVPVNCQTPGTTVSGPYGTSNIWDNIGNGRFVADAYVKTGSDGYVAPRCG
>CP032698.1|AYG81288.1|3833213_3833759_-|hypothetical-protein
MSENKGESESDAAGRGDGGGATATPAGPRPEPIRFFGTTWVDHDHGYGLRRAGAAIGSLAAAVAACFVLRFAYEGLRLANTGTFVNVLVVVMFAICSALAFRKTWEGFSTRPSDPDADRSLQGLKAIGFIGSLLAYFFRTFTEAPGESLHRTEYETARTQYERRRGNRTGNPSGKKRPKRR
>CP032698.1|AYG81287.1|3831949_3832702_-|putative-methyltransferase
MAMDQTRAHSFNAAAAQYAANRPSYPELLLDALEELAGRPLHDARVADIGAGTGIASALLHERGARVIAVEPGEGMAAQFRRTNPGIPLVRGDGNRLPLATASADFLTYAQAWHWIDPAVAGPEARRVLRPGGALALWWNLTDHSTQWQSAQEARLRDFFRTDPTERAARGGHYGAEIPGLDFTERRIPHTRRVPLATHLANLGSHSAFLVLGEERTKEFMEREHDLLSAAFPDGMVEETYVVHLSLALT
>CP032698.1|AYG81286.1|3830597_3831323_-|Ribosome-associated-ATPase
MTATALAAVRAGRTVLRDLDFTVPRGRITGLLGPSGCGKSTLMRAIVGTQANVTGTLTVLGAPAGTPTLRERIGYVTQAPSIYQDLTVRQNLNYFAAVLHPGRPHREARAEAVTRAITDVDLTSHADHLAGRLSGGQRSRVSLAVALLGTPELLVLDEPTVGLDPVLRRDLWDLFHTIADTRGTTILISSHVMDEAERCRHLLLLREGTLLAEDTPDALRARTHTETVEEAFLHLVARATP
>CP032698.1|AYG81285.1|3829746_3830484_-|Inner-membrane-transport-permease-YbhR
MTASRTLATAARVLRQLRHDPRTIALLLVIPSLMIILLRYVFDADPAVFNSIGASLLGIFPLITMFLVSSIATLRERTSGTLERLLAMPLGKGDLIAGYALAFGALAVLQSLIATGISLWLLDLNVVGSPWLLLLVALLDALLGTALGLFVSAFAASEFQAVQFMPAVIFPQLLLCGLFTPRDTMQPVLRALSDVLPMSYAVDAMTQVLHHPEATATFARDTGIVATVALVVLALGAATLRRRTP
>CP032698.1|AYG81284.1|3828804_3829614_-|Pyrroline-5-carboxylate-reductase
MTQTVAVLGTGKIGEALLSGMIRAGWHPANLLVTARRPERAEELRTRYGVDAVTNAEAAKRADTLILAVKPQDMGALLDELAPHLTDDRLVISAAAGIPSTFLEARLAAGTPVVRVMPNTPVLVDEGMSVISAGSHATPDHLAHAEEIFGGVGKTLRVPESQQDAATALSGSGPAYFYYLVEAMTDAGILLGLPRAQAYDLIVQSAIGAAVMLRDSGEHPVKLREAVMSPAGTTISAIRELENHGVRAALIAALEAARDRSRELASGTN
>CP032698.1|AYG81283.1|3827725_3828547_+|hypothetical-protein
MRSGWCGMAVRGPTGVGAHVGQLGEHYVPGKSVSTLGRRPGAGRSEGRRTPLASCFRPRRGWRNGRSGGGVVRPSVAAMRSLLRIAVAPATLLVLGMAVAPGTAYAMDGDERIARIRLRVVEAVNEKTRDEIQRAHACPGSHSADEVDRLEAKLRDGCRLAQDLRHVRAAHGRGRAVHAVGGGSGDGPGAPGDGPGAPGGPGALADGPSGSRGGPGGSGGGGADADVQGSVFQAARAELPRLPVGVLSLVGGGALALVGGGMAAVAVGWLPRR
>CP032698.1|AYG81282.1|3821303_3821948_-|6-phosphogluconate-phosphatase
MRYDLIIFDNDGVLVDSEPISNTILSGYLTELGHATSYEDSLRDYMGAAVHRVHDLIEERTGRKLPADFDETLHARIFAAFERELQPVPGVTDVLGKLVAEGVPYCVASSGTHERIRVGHRRTGLDEWFEEEWVFSAEDVGRGKPAPDLFLRAAERMGVAPERCVVIEDSRLGIEAARAAGMDVYAFTAMTPADRLEGANGHFGDMGQLLGLLA
>CP032698.1|AYG81292.1|3839009_3839729_-|HTH-type-transcriptional-regulator-BetI
MTEAAGGTGPGSGPDSGSAPGPGPGPDSAPGTGPDSGAGPAAPRRRGRPPRAVAEAGPGTRERILSAARTEFSGRGYDKTSMRGIAKTAGVDASLVHHYFGTKEAVFAAAIEVDFEPALTADAILGDSLDGVGERLARHFLGIWENPVTRTPLIAVIRSALTHEAAAKVLRGVVLRRLLERVAADLAVPDPRFRAELAASQMMGIVIMRYVLEVEPLASVPAERIVAEVGPTLQRYLTE
>CP032698.1|AYG81293.1|3839725_3840535_-|hypothetical-protein
MVRIPDAKVALSTASVYPESTATAFEIAARLGYDGVEVMVWTDPVSQDIEALRRLSDHHQVPILAVHAPCLLITQRVWSTDPWVKLQRARAAAEKLGASAVVVHPPFRWQRQYSRDFVSGIWRMADETDVRFAVENMYPWRYRDREMLAYAPDWDVTKDDYRHFTVDLSHAATSRTDAMAMVDRMGDRLAHVHLADGRGSAKDEHLVPGRGTQPCAELLERLALTGFDGHVVIEVNTRRAMSAAEREADLAEALAFTRLHLASAPARRA
>CP032698.1|AYG81294.1|3840712_3841624_-|Exopolyphosphatase
MGSNTVHLLVVDAHAGAAPLPAHSHKAELRLAELLDEDGAIGAEGIDRLVATISEALLSAEDKGVQELLPFATSAVREASNVDQVTARVRDETGVDLSVLSGEEEARLTFLAARRWYGWSAGKLLLLDIGGGSLEVAYGIDEEPDAAVSLPLGAGRLTAGWLPGDPPDPADVRALRRHVRAQIAGTVGEFARSGRPDHVVATSKTFKQLARIAGAARSSEGAYVQRTLSRTSLEEWVPKLAAMTTEQRTTLPGVSPGRAPQLLAGALVAEGAMDLFAVDELEVCPWALREGVILRHLDHLPAV
>CP032698.1|AYG81295.1|3841643_3842513_+|hypothetical-protein
MDRTLLRVRRRPRTYAGGVPKTKKAKPGKAKALKNAAPVVQDEQGIDFPRAWVEFPDPADDEQVFRCDLTWLTSRWTCIFGSGCQGIEAGRADDGCCTLGAHFSDEDDEKRVAGHVARLTPELWQFHDVGTETGWIQTDDDGDRQTRRWNGSCIFQNRPGFPGGMGCSLHILALKEGKEPLETKPDVCWQLPVRRTYDWIERPDDTKVLQISIGEYDRRGWGPGGHDLHWWCTSATSAHGAGEPVYVTYRPELTELMGEEAYAVLVEQCEARLASLLPLVAPHPADPAR
>CP032698.1|AYG81296.1|3842548_3844132_-|hypothetical-protein
MAQRPPARYEAYLDGLFTYCLSVLCDHDEATAALGDILAVSERQYARCPAAEAERRAWLYALARWACLRKLAERRRDRQGAHTGRAPEAAPAVEVSEDERERRRRELALLAWPEAAGTTPEQREALELAVRHQLGAREVASVLGMNYPAARELLAAGACEVERTRAALAVVEMGGCPTVAQLTGDHQVLLSAALRRELVRHVDDCPRCRRAAESAGAAGPWPGSTVTPAALPLAKAPRAAAQAAMMHVPRTRGGAPRFDRTGFPMDPKDRAARRDRLRARAVTTTVVATVVAAPVFALWAAYRSAPATGEPQAGAAKVTASEADGPGGRPYDRYENAGNARAQPDTRFTSGSRAPDVSVEVISPTTAPAGPGRLAVAASSAGDTTVLTLTSTGGAPVDWSLRSRARWLTISQSAGRLAPGQSVTVYIRVDHAEEPHRAWSVRVDVEPSGAAVRISGDGTPVAPPSSPDPGGSGHPGPPGSSATPTTGPTQTPGSPTPTPSPSSPSQSPTPTDTPSPTGTPPSPSQSG
>CP032698.1|AYG81297.1|3844313_3845930_+|DNA-repair-protein-RadA
MAFHGRPITHCANGRERSGRRGVDHVHPNGGARKPEPRAGPARGPARGPDPVPLPAPIGRPGGIVSGPLYGDAMAARTKSAKDRPSYRCTECGWTTAKWLGRCPECQAWGTVEEYGAPAVRTTAAGRVSTAALPIGEVDGRQATARTTGVSELDRVLGGGLVPGAVVLLAGEPGVGKSTLLLDVAAKAASDDHRTLYITGEESASQVRMRADRIKALNDHLYLAAETDLSAVLGHLDAVKPSLLVLDSVQTVASPEIDGAPGGMAQVREVAGALIRASKERGMSTLLVGHVTKDGAIAGPRLLEHLVDVVLSFEGDRHARLRLVRGVKNRYGATDEVGCFELHDEGITGLADPSGLFLTRRDVAVPGTCLTVTLEGRRPLVAEVQALTVDSQIPSPRRTTSGLETSRVSMMLAVLEQRGRITALGKRDIYSATVGGVKLSEPAADLAIALALASAASDTPLPKNLVAIGEVGLAGEVRRVTGVQRRLAEAHRLGFTHALVPTDPGKVPAGMKVTEVADMGDALRVLPRGRRAQAPREE
>CP032698.1|AYG81298.1|3846031_3847156_+|DNA-integrity-scanning-protein-DisA
MAANDRASAPGKSGTGSGNEALMRAALSAVAPGTALRDGLERILRGNTGGLIVLGLDKTVDSMCTGGFVLDVEFAATRLRELCKLDGALVLDKDITKIHRAGVQLVPDAGIPTDETGTRHRTADRVSKQCNYPVVSVSQSMRLIALYVNGERRVLEESAAILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIAGVEPERELVVRDYVPEPTAKRSRTVDEALRELNDLTHAELLELPIVARALGYSGSPETLDSAVSPRGYRLLAKVPRLPGAIIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV
>CP032698.1|AYG81299.1|3847485_3847698_+|hypothetical-protein
MRASTEQLRGAGNCATSHLRPADENAFFKSGHGPQAESGFRGAGNCAAGHARPGRGRDPPEGFGEGWGGG
>CP032698.1|AYG81300.1|3847694_3848618_-|hypothetical-protein
MMIRKTWPEWRRVGRELAPISRKVRCVGSLRNPVGPLPSSIYWRRRAVALSLIALLAILVLWFATSGGGDNKGGSSKGPNPTQSITPGPTGSGPAISTAPGGRDTSSGSGGSGGSGGSGGSAGSGGPGGSGGANSADGGTSTGSGGSDGANSGSGGGSSGGGGEGTNRVPAGSPLPICAPGSLSLTLRSTKTTFGPGEKPRIEVVVKNNSASTCKADLGPKGAVVTVTSAGNDRVWSTDDCPSGDPALFFQVPGGATITHAVEWDRSKSAPGCATPPAGSVGPGTYLLEAHFPGLPVARASFALSKD
>CP032698.1|AYG81301.1|3848705_3849332_+|Undecaprenyl-diphosphatase-BcrC
MDSELYRNITDFAHDMPSWVQSFVEVWTELGLLLFGVLFACAWWRARRRDTTSFALALLAPLATAAAYLCSEVMKSLIDEERPCRAVAGAATSLIACPVNGDWSFPSNHATIAGAAAVALALAWSRIWMITVPMALAMAFSRVFVGVHYPHDVAAGLVLGTVIALIVVKVGTRPVRALAESMRTSDITPVAWFTGPGARVHARQHARR

Crispr_ID: CP032698_29

• CRISPR_ID: CP032698_29
• CRISPR_location: 3879954-3880053
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of CP032698_29

Consensus_repeat	Method
ACCCCTGGGGCTCCGCCCCAGACCCC	CRISPRCasFinder

spacers of CP032698_29

>29.1|3879980|48|CP032698|CRISPRCasFinder
GACGCGTTCACCCACCCACCCGCCCGTGACGGGGGTTGGATAGCCCGG

CRISPR arrays and Neighbor proteins around CP032698_29

CRISPR arrays

The CRISPR arrays of CP032698_29

>merge|CP032698|29|3879954-3880053|CRISPRCasFinder
ACCCCTGGGGCTCCGCCCCAGACCCCGACGCGTTCACCCACCCACCCGCCCGTGACGGGGGTTGGATAGCCCGGACCCCTGGGGCTCCGCCCCAGACCCC

>CP032698|29|22|3879954-3880053|CRISPRCasFinder
ACCCCTGGGGCTCCGCCCCAGACCCC	GACGCGTTCACCCACCCACCCGCCCGTGACGGGGGTTGGATAGCCCGG
ACCCCTGGGGCTCCGCCCCAGACCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81337.1|3887168_3887849_-|Choline-transport-system-permease-protein-OpuBD	unknown	unknown	gnl|CDD|224095
CP032698.1|AYG81335.1|3885375_3886371_-|Choline-binding-protein	unknown	unknown	gnl|CDD|270324
CP032698.1|AYG81324.1|3872877_3874080_+|Low-specificity-L-threonine-aldolase	unknown	unknown	gnl|CDD|224919
CP032698.1|AYG81333.1|3882818_3884060_-|hypothetical-protein	unknown	unknown	gnl|CDD|375319
CP032698.1|AYG81320.1|3868073_3869102_-|Nicotinate-nucleotide-pyrophosphorylase-[carboxylating]	unknown	unknown	gnl|CDD|236125
CP032698.1|AYG81331.1|3880458_3881601_+|NADH-quinone-oxidoreductase-subunit-4	unknown	unknown	gnl|CDD|223722
CP032698.1|AYG81322.1|3870813_3871827_-|Pantothenate-synthetase	unknown	unknown	gnl|CDD|376824
CP032698.1|AYG81338.1|3887999_3889145_+|Carnitine-transport-ATP-binding-protein-OpuCA	unknown	unknown	gnl|CDD|213262
CP032698.1|AYG81340.1|3890433_3892275_+|Lysylphosphatidylglycerol-biosynthesis-bifunctional-protein-LysX	unknown	unknown	gnl|CDD|235095
CP032698.1|AYG81323.1|3871823_3872747_-|hypothetical-protein	unknown	unknown	gnl|CDD|227782
CP032698.1|AYG81328.1|3876788_3877463_-|Transcriptional-regulatory-protein-DegU	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG81329.1|3877598_3878810_-|Nitrate/nitrite-sensor-protein-NarX	unknown	unknown	gnl|CDD|226951
CP032698.1|AYG81339.1|3889170_3890283_-|hypothetical-protein	unknown	unknown	gnl|CDD|223700
CP032698.1|AYG81326.1|3874528_3875644_+|Transcriptional-repressor-SdpR	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|197713
CP032698.1|AYG81325.1|3874145_3874364_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81334.1|3884167_3885289_-|hypothetical-protein	unknown	unknown	gnl|CDD|274008
CP032698.1|AYG81332.1|3881677_3882730_-|1,3,6,8-tetrahydroxynaphthalene-synthase	unknown	unknown	gnl|CDD|238427
CP032698.1|AYG81327.1|3875684_3876659_-|2-haloacrylate-reductase	unknown	unknown	gnl|CDD|176189
CP032698.1|AYG81336.1|3886496_3887165_-|Glycine-betaine/carnitine/choline-transport-system-permease-protein-OpuCB	unknown	unknown	gnl|CDD|224095
CP032698.1|AYG81321.1|3869104_3870817_-|L-aspartate-oxidase	unknown	unknown	gnl|CDD|236102

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP032698.1|AYG81326.1|3874528_3875644_+|Transcriptional-repressor-SdpR	csa3	COG0640_csa3_CAS-I-A	1.5e-13	45.9	3.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81337.1|3887168_3887849_-|Choline-transport-system-permease-protein-OpuBD	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	2.9785e-54
CP032698.1|AYG81335.1|3885375_3886371_-|Choline-binding-protein	gnl|CDD|270324	cd13606, PBP2_ProX_like, Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold. This group includes periplasmic substrate-binding component of ABC transport systems from gram-negative and -positive bacteria that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.4746e-83
CP032698.1|AYG81324.1|3872877_3874080_+|Low-specificity-L-threonine-aldolase	gnl|CDD|224919	COG2008, GLY1, Threonine aldolase [Amino acid transport and metabolism].	7.55088e-36
CP032698.1|AYG81333.1|3882818_3884060_-|hypothetical-protein	gnl|CDD|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	9.52475e-10
CP032698.1|AYG81320.1|3868073_3869102_-|Nicotinate-nucleotide-pyrophosphorylase-[carboxylating]	gnl|CDD|236125	PRK07896, PRK07896, carboxylating nicotinate-nucleotide diphosphorylase.	1.88201e-152
CP032698.1|AYG81331.1|3880458_3881601_+|NADH-quinone-oxidoreductase-subunit-4	gnl|CDD|223722	COG0649, NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion].	1.58599e-145
CP032698.1|AYG81322.1|3870813_3871827_-|Pantothenate-synthetase	gnl|CDD|376824	pfam02569, Pantoate_ligase, Pantoate-beta-alanine ligase. Pantoate-beta-alanine ligase, also know as pantothenate synthase, (EC:6.3.2.1) catalyzes the formation of pantothenate from pantoate and alanine.	1.45602e-133
CP032698.1|AYG81338.1|3887999_3889145_+|Carnitine-transport-ATP-binding-protein-OpuCA	gnl|CDD|213262	cd03295, ABC_OpuCA_Osmoprotection, ATP-binding cassette domain of the osmoprotectant transporter. OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	9.83945e-146
CP032698.1|AYG81340.1|3890433_3892275_+|Lysylphosphatidylglycerol-biosynthesis-bifunctional-protein-LysX	gnl|CDD|235095	PRK02983, lysS, bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX.	0
CP032698.1|AYG81323.1|3871823_3872747_-|hypothetical-protein	gnl|CDD|227782	COG5495, COG5495, Uncharacterized conserved protein [Function unknown].	2.11955e-52
CP032698.1|AYG81328.1|3876788_3877463_-|Transcriptional-regulatory-protein-DegU	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.09554e-72
CP032698.1|AYG81329.1|3877598_3878810_-|Nitrate/nitrite-sensor-protein-NarX	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.93548e-46
CP032698.1|AYG81339.1|3889170_3890283_-|hypothetical-protein	gnl|CDD|223700	COG0627, COG0627, Predicted esterase [General function prediction only].	2.28014e-07
CP032698.1|AYG81326.1|3874528_3875644_+|Transcriptional-repressor-SdpR	gnl|CDD|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	9.62437e-14
CP032698.1|AYG81334.1|3884167_3885289_-|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00338748
CP032698.1|AYG81332.1|3881677_3882730_-|1,3,6,8-tetrahydroxynaphthalene-synthase	gnl|CDD|238427	cd00831, CHS_like, Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy, after the starter molecule is loaded onto the active site cysteine, a carboxylative condensation reation extends the polyketide chain. Plant-specific PKS are dimeric iterative PKSs, using coenzyme A esters to deliver substrate to the active site, but they differ in the choice of starter molecule and the number of condensation reactions.	3.26602e-68
CP032698.1|AYG81327.1|3875684_3876659_-|2-haloacrylate-reductase	gnl|CDD|176189	cd05286, QOR2, Quinone oxidoreductase (QOR). Quinone oxidoreductase (QOR) and 2-haloacrylate reductase. QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. 2-haloacrylate reductase, a member of this subgroup, catalyzes the NADPH-dependent reduction of a carbon-carbon double bond in organohalogen compounds. Although similar to QOR, Burkholderia 2-haloacrylate reductase does not act on the quinones 1,4-benzoquinone and 1,4-naphthoquinone. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which have a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	1.03109e-95
CP032698.1|AYG81336.1|3886496_3887165_-|Glycine-betaine/carnitine/choline-transport-system-permease-protein-OpuCB	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	4.65394e-56
CP032698.1|AYG81321.1|3869104_3870817_-|L-aspartate-oxidase	gnl|CDD|236102	PRK07804, PRK07804, L-aspartate oxidase; Provisional.	0

Protein sequences

>CP032698.1|AYG81329.1|3877598_3878810_-|Nitrate/nitrite-sensor-protein-NarX
MQRLYDFIRRHPTGVDTFWAVILVGFSCLQIVETPAHPRQAAWGIQALVALGMGAVVALRRRVPEKMLLLVIGLGLVQVALNVHPQTADFAMLVIVYTVASAGERWASRLALVGGLFAAPVAQMRWMEMAGGTTGTPERIFFVVIMTVPFVLAWVLGDSMRTRKAYFAQLEERASRLEREREAQAKVAVAAERARIARELHDVVAHNVSVMVVQADGAAYVMDTSPDQARTALETISMTGRQALAEMRRLLGVLRTGEHQEAGEYVPQPDVQQIEDLVETVRGAGLTVDFKIEGTPRPLPSGVELTAYRIVQEALTNTRKHGGPDVGASVRLVYFDDGLGLLVEDDGRGAAHEMYEDGGADGQGHGLIGMRERIGMVGGTLDAGPRPGGGFRISALLPLKPAH
>CP032698.1|AYG81328.1|3876788_3877463_-|Transcriptional-regulatory-protein-DegU
MTIRVMLVDDQVLLRTGFRMVLAAQPDMEVVAEAGDGAEAIEILRATAVDVVLMDVRMPRLDGVEATRRICEAPEPPKVLILTTFDLDEYAFSGLKAGASGFMLKDVPPAELLAAIRSVHSGDAVVAPSTTRRLLDRFAPMLPSGNKEPEHRQLERLTEREREVMLLVAQGLSNGEIAARLVLSEATVKTHVGRILTKLELRDRVQVVVLAYETGLVRAGGGAN
>CP032698.1|AYG81327.1|3875684_3876659_-|2-haloacrylate-reductase
MRAIRFDEFGGPEVLRLVETEVPAPGPGEVGIDVAYVGVNFADLKARSVGYRVEALPFVPGLELSGRIRALGAGVEGLVVGQEVAAMTEGGAYAEVALAPAVTVFPLPAGVSPRTAATLPTVLPTAHALIHEVGRLRAGESVLVQGAAGGVGTVSGRLAKLAGAGAVYGVVSSEAKADYARKHGYDDAFLTDTFDTEVLRATGGRGVDLVLDPVGGATLRRGLESLALFGRLVSYGNASGEEPWQVGQGELYARGRSVSGFSILGLAAGDPEALRVIADRALRLVTSGEVELPVTAEFSLEQAVSAHELMESRSSTGKLLLRVD
>CP032698.1|AYG81326.1|3874528_3875644_+|Transcriptional-repressor-SdpR
MSVTIDITGLPPERIGFAISPLAELGLALHALSEPGHHPGLHGWVTATAAALKPDLADRLHEAEFLWRHTFSDVFMPFAGIPGRDGGTGATLAEDLDLLDRLSNERFASAALEFTCNLYTVKTPSPLHDPAMRARALELAANRGPRVVDFTRRLLDDPASVRAWLRRLLEDCDQAFFADTWRRMRVQLAADARHKAELLRHKGLTEAVQAVSAALSVDDGGNRIGVDKLSEGHTTALDPEPGAGLTFMPTSFGWPHLMVLHAPGWRPVIHYPVHGPELPSPASVELLKRRMEALAHPMRMRLCRNLARSPNTTGELAEQHGISAPEVSRHLAVLKRAGLLTTRRRGRYVLHQLDLTVVARLGSDFLEGVLR
>CP032698.1|AYG81325.1|3874145_3874364_-|hypothetical-protein
MQQHMIDSYRAARLGAPAPPVPGTHDVATLRGIRDRRRFEAVLAGRLATGRLRAALAHLLTPHHHRHPPACH
>CP032698.1|AYG81324.1|3872877_3874080_+|Low-specificity-L-threonine-aldolase
MADTERASRPETTITTPGGAPEEDPERARRHRMAVFGGAERKLADQSVDHSLAERLAALVADAGEVYDLAESPDIYGDGVVAELERRTAEELGFPAAAFFPSGTMAQQVALRCWAARTGNPTVALHPLAHPEVHERQAFSQVSGLRTVHLTDEPRLPNAAEVLDFEEPFGTLMLELPLRDAGHVLPSWEELVAVVEAARERDAVVHFDGARLWETTPHFGRPLREIAGLADSVYVSFYKTLGGLSGAVLAGPESLIAEARTWRHRYGGQLFQQFPAALAGLLGLRKVLPEIPSYVTHAKVVAQAIGEGFAQAGVAWFRVHPEPPHTHEFQVWLPYDAEVLSAAALRQAEESGVCLFRRWLPSPSGPQGLSFTEVTVTAPGLAWTAEDVRTAVADFVRRLR
>CP032698.1|AYG81323.1|3871823_3872747_-|hypothetical-protein
MNAPPEHRKEHSPADRPARLAVGVVGAGRVGPALAAALQLAGHRPVAVSGVSDASVRRAAALLPDVPLLPPAEVLARAELVLLTVPDDALPGLVEGLAETGAIRPGQLLVHTSGRYGTAVLDPARRAGALPLALHPAMTFTGTAVDVQRLAGCSFGVTAPDELRLAAEALVIEMGGEPEWIDEEARPLYHAALALGANHLVTLVAQSLELLSQAGVAHPDRMLGPLLGAALDNALRSGDAALTGPVARGDAGTVAAHVAELRKHAPGTVAGYLAMARTTADRALAHGLLKPELAQDLLGVLAEGESR
>CP032698.1|AYG81322.1|3870813_3871827_-|Pantothenate-synthetase
MTTQPASTGRTALVRTAAELAALERTGRRAVVMTMGALHEGHATLIRTARTLAGPAGQVVVTVFVNPLQFGAGEDLDRYPRTLDADRAIAEREGADAVFAPSVDEVYPGGEPQVRVTAGPMGELLEGASRPGHFDGMLTVVAKLLHLTAPDVALYGQKDAQQLALIRRMVRDLNFPVEIVGVPTVREDDGLALSSRNRYLSPAERSAARALSRALFAARDRLAAEHALHARATAGGAAPGRADALTAIGEARAAADAHAVAVAAPSPAAIRAVAQGVLDDAAKAEPPVVADYLALVDPATFREAPEGFAGEAILAVAARVGTTRLIDNIPLTFGAPE
>CP032698.1|AYG81321.1|3869104_3870817_-|L-aspartate-oxidase
MTSTGIRLDAPAPGWAIDADVVVVGSGVAGLTAALRCTAAGLATVVVTKARLDDGSTRWAQGGIAAALGEGDTPEQHLDDTLVAGAGLCDENAVRLLVTEGPGAVRRLIDTGAHFDTDDSGTISLTREGGHHRRRIAHAGGDATGAEISRALVEAVRTQAVRTIENALVLDLLKDAEGRTAGITLHVMGEGQHDGVGAVRAPAVVLATGGMGQVFSATTNPSVSTGDGVALALRAGAEISDLEFVQFHPTVLFLGADSEGQQPLVSEAVRGEGAHLVDAYGTRFMLGQHQLAELAPRDIVAKAITRQMQAQGAENMYLDGRHFGADMWEHRFPTILAACRSHGIDPVTEPIPVAPAAHYASGGIRTDLRGRTTVPGLYACGEVACTGVHGANRLASNSLLEGLVFAENIAADIAANGADGSAPDAPTPVPHTAVDAERDGGPVPLLDPAARIQIQRIMTNGAGVLRSAESLAGAAERLEAIRADERKAAVPGVEAWETTNLLLVARVLVAAAAAREETRGCHWREDRPDRDDAAWRRHLVVRLTPGRTLDIRPTPSATFPPTVTATPLEP
>CP032698.1|AYG81320.1|3868073_3869102_-|Nicotinate-nucleotide-pyrophosphorylase-[carboxylating]
MSTPEELRPQPVDVPLIQIGAPAQGGGCGDDCGCGGGEEVYECGLDPALAALLAESGLDPVQVEDIAHLAIEEDLDGGFDVTSAATVPQDAVATGDFTAREAGTVAGLRVAEAILSIVCTEEFEVERHVADGDRVEAGQKLLSVTTRTRDLLTGERSALNLLCRLSGIATATRAWADAVEGTGAKVRDTRKTTPGLRALEKYAVRCGGGVNHRMSLSDAALVKDNHVVAAGGVAEAFKAVRDRFPELAIEVEVDTLAQVTEVLDAGADLILLDNFTPAQTAEAVALVAGRAMLESSGRLTLANAAAYAATGVDYLAVGALTHSSPILDIGLDLREAGREGSA
>CP032698.1|AYG81331.1|3880458_3881601_+|NADH-quinone-oxidoreductase-subunit-4
MTETTVGIGGGAESTDMVLNIGPQHPSTHGVLRLKLVLDGERIQQAEPVIGYMHRGAEKLFEARDYRQIVMLANRHDWLSAFSNELGVVMAVERMLGMEVPERAVWTRTLLAELNRVLNHLMFLGSYPLELGGITPVFHAFREREELQAVMEEISGGRMHYMFNRVGGLKEDLPLGWLGRVRHAVASVRSRMDVYDGLVLGNEIFRARTRNVGVLPAEAVHAYGVSGPIARASGVDFDLRRDEPYLAYGELQDTLKVVTRTEGDCLARFECLLEQTHNALDLADACLDRMAGLPPGPINQRLPKVLKAPEGHTYAWTENPLGVNGYYLVSKGEKTPYRLKLRSASYNNIQALAVLLPGTLVADMVAILGSLFFVVGDIDK
>CP032698.1|AYG81332.1|3881677_3882730_-|1,3,6,8-tetrahydroxynaphthalene-synthase
MPAHIAPPCVVLPGNVVTTDEICADIRRAHPDLPRLEAMLRVARATTVRTRNFTRPLNAPTVAGNAMVEERNRTAYEDALELATEAGRRALAATGLRPSDIDAIVTSHTTSWTVPSLDVHLVGALGLPPAVRRHPLATLGCAGGAQGLVRAHQDIAAHPGANVLVVTAECLSAATYNHEDTSLESMVYKVLFGDGAAATVVSGRPAWDGPSFVVEDVMEYVLPDSSDRYRGRLSGAGLHFDSTRAATAAFNDCLPELAKWLDGRPLDFAVVHPGGPRILDDTAAGLALDATDLRHAWESLAHNGNLGGSAVLDVLARTAATTPPADGAPGLVIAFGPGFVLAAARGHWAN
>CP032698.1|AYG81333.1|3882818_3884060_-|hypothetical-protein
MTTTHEHRRPDGERPGRPVAYGTMRGTGAEVEDGTGTGAEDGAGTRGKGLRPVPRPLHRGECRYLPQSPDARDRRHPVGRSPRAATAPIVIGNPAVFPGGTDADNCPAVRFARHDRPHRPPPPRKALPLHLAAADRAALRALLRERRAAVSPASLGFPPRQPGPGRRAAGLSQEQLDLLLERTPGTYNRFENGQLASPSAELLSAVATVLRFDEQEWVFLWRLTRRENPPSPLHRASGLSVPGEWQRVVDGISGALAYINDAEWNLLAHNKEFAALFPGGEPPANPMRWMLLDPQAREVVLADWARSWAPVVMPQLRHAVELRPENAALARLEDDVRRDPVAGPLYEAAASAPIAYPDGSERPLNHALYGPGWVTTCVAQPVTSPGARVMLLLYTPGDSLASRSSFPEAPQMS
>CP032698.1|AYG81334.1|3884167_3885289_-|hypothetical-protein
MPRGRHRHSPPLHRLLQPSAVAGVSVICAGGAWLVDQPAMLRALAAAAAAACVTGSVLMRAWDRAAGRRVAELTRSRAADQWRTEERIAELETELEESRELRGRLDAKLRTKRMELAGLRGEHAALLRRYATAETERASALEGRRQLALESTGPKALMPSGSTPTPASYLAAARALESLSLSAERQAKARAEAEASRTREPGRPQPSGEPRPSGESRSSGERPSSGRSRPSPESRPSREDEEPQGKHAAVLGNGEHSRPSAALTTGPRRAELPAPPAPVAAAVVPHPARRAVRPEGSFDFFGTGGAQPGESAERKAAAIEAVQDEDLADVVGAEVLANRAQQGPDKVVGEVIDLTVHDETEQLDVAVLRTAIS
>CP032698.1|AYG81335.1|3885375_3886371_-|Choline-binding-protein
MSKILRTTGAVLGTLALAGTLAACGGDSLEKSQDKSSSSTSGGSSSTSGGKKGSLVVGAAGFTESAVLAELYSQVLADAGYATSITTVKNRELYEPALEKGEIDVVPEYAATLTEFLNAKVNGDKAKDKPLASSDVTATLAELTKLAGPRGLKVLPAGEAVDQNAFAVTKEFATKNNLKSLSDLGASKVKVKVAAGDECKIRPFCAPGLTSKYGIDVTGIDPKGVGTPGAKQAVKDGVDQLVLTTTTDASLDTYGLVLLQDDKKLQNADNVLPVVNAKDAAAPEISDALGKLTKALTTADLVDLNRKVDAERAKPADVAKAYLQSKGLIKK
>CP032698.1|AYG81336.1|3886496_3887165_-|Glycine-betaine/carnitine/choline-transport-system-permease-protein-OpuCB
MGVFTQAWTWLATGSHWSGEDGAWHRLGEHVYVSALALLVSCLIALPLALWLGHIGKGGALAVNLSNVGRAIPVFAVLALFMVTPLRNAGYLPTVIALVLFAVPPLLTNAYVGMREVDPAAVEAARGMGMSGRQLFLQVELPLAYPLIMTGLRSAAVQIIATATIAAMAGLGGLGRIVTEGFAVYDTPQVVAGAMLVAALALLVEGVLVAVDRIFSPVRGRS
>CP032698.1|AYG81337.1|3887168_3887849_-|Choline-transport-system-permease-protein-OpuBD
MARNCLAANDWICWEYVSSRSQELTDATVQHIWITAVSVLIGLLVAFPLALLARGRKGVAATVLGITTVLYTVPSLAMFALLLPLFGLSAGLVITGLVLYSLTILVRNILAGLESVPPDALEAARGMGYGRIRLLFEVELPLALPALMAGLRIATVATVALTTIGSLVDHGGLGNLIEQGLPTFFKAQILTASVLCVVLAIAADLLLLGLQRLLTPWTRIRTAKAG
>CP032698.1|AYG81338.1|3887999_3889145_+|Carnitine-transport-ATP-binding-protein-OpuCA
MIRFEHVTKRYADGTIAVGDLSFEVAGGELVTLVGPSGCGKTTTMKMVNRLIEPTEGRIFVDGEDISTVDPVQLRRRIGYVIQQVGLFPHKTVLENTATVPHLLGVKKAKAHARAAELLDLVGLDPKTYGSRYPEQLSGGQRQRVGVARALAADPPVLLMDEPFGAVDPVVRERLQNEFLRLQSQVRKTVLFVTHDIEEAVRLGDRIAVYGQGAIEQFDAPAAVLGAPATPYVADFVGADRGLKRLSVTPIEEGDLDQPPVVHLDDPLPADIARWAVVLDGEDNLHGWISGEQARLGKGTVREHARRMEAWLPVGASLKQAFATMLQHDAGWIAVIDREERGRFLGVLTPARLHEALRRSIDADAQAVPRTEVTVESVSSR
>CP032698.1|AYG81339.1|3889170_3890283_-|hypothetical-protein
MGLTSNKVLALAAFLAVVLFAVTIWLWPRLARRSWKAVTGRIGLLLATQLAIFASVGLAANNSFLFYGSWADLFGQEQDLGTVVDHSAGGKNIKVVGVQKPDTPGAGKPQLGGEIQKIVLGGEKSKITSPAYVYLPPEYFQKAYEHKTFPASIVLTGYPGTAENLLKGLRYPKTAWAQAKQKKMQPMILVMMRPTVAGQRDTECVDIPGGPQTETFFAKDVPDAISANYRVGTKPANWGFIGNSTGGYCALKIGMHHPERFAASAGLSAYYDAADDPTTGDLFHGDKHERNRANLLWSLDHIKPAPSSFLVTSSLSGEENYKPTQSFIKKVKAPGRVSSITLDSGGHNFNTWRREIPPTLEWISGRLSAN
>CP032698.1|AYG81340.1|3890433_3892275_+|Lysylphosphatidylglycerol-biosynthesis-bifunctional-protein-LysX
MSVRIDGDKNGSVPTRVRKVLGGPRAESVPKLVGTACTIVGLLDVAAGVFDRVRHSRFHTVSEVLPGTFGPFAAAVALSAGILLLLLAHGLKRRKRRAWRAAVVLLPIGAVAQFWYRHSVVGVLISLVLLTLLVRHRSEFNALPDPRSRWKAVANFFLMGASSLGLGLVIVSVHPHRTVGNPSIVDRIQHVMYGLFGFEGPVEYQGKTSWTVGYSLGALGLLTAVTTIYLAFRPEHPAARLTEDDEHKLRDLLAKHGARDSLGHFALRRDKAVVFSPSGKAAVTYRVVSGVMLASGDPIGDVEAWPGAIERFMDEAKAHSWTPAVVGCSETGGEVWTRETGLDALELGDEAVVDVADFSLSGRAMRNVRQMVKRIERNGYETRVRRVRDLSDGELERIRRAAEDWRGTDTERGFSMALGRIGDPNDGDCVIATAHKADEEGAAPGPFGDLKAILHFVPWGKDGMSLEMMRRDRSADPGMNELLIVASLQACEKIGVRQVSLNFAMFRSALARGEKIGAGPVLRLWRGLLVFLSRWFQIESLYKFNAKFQPRWEPRFMVYRAHADLPRIGFAVMQAEGFVNLGLPGPLARLTRAARRDRACAHVPPKEREMRAA

Crispr_ID: CP032698_30

• CRISPR_ID: CP032698_30
• CRISPR_location: 3919595-3919692
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_30

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGGGG	CRISPRCasFinder

spacers of CP032698_30

>30.1|3919621|46|CP032698|CRISPRCasFinder
CCGCACCCTTCAACGCGCCACGGGCGGGTGGGTGGGGAAGGTGCCT

CRISPR arrays and Neighbor proteins around CP032698_30

CRISPR arrays

The CRISPR arrays of CP032698_30

>merge|CP032698|30|3919595-3919692|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGCCGCACCCTTCAACGCGCCACGGGCGGGTGGGTGGGGAAGGTGCCTCGGGGTCTGGGGCGGAGCCCCAGGGG

>CP032698|30|23|3919595-3919692|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGG	CCGCACCCTTCAACGCGCCACGGGCGGGTGGGTGGGGAAGGTGCCT
CGGGGTCTGGGGCGGAGCCCCAGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81370.1|3923197_3923791_-|RNA-2',3'-cyclic-phosphodiesterase	unknown	unknown	gnl|CDD|274058
CP032698.1|AYG81359.1|3911355_3911958_-|hypothetical-protein	unknown	unknown	gnl|CDD|224609
CP032698.1|AYG81373.1|3925929_3926112_+|hypothetical-protein	unknown	unknown	gnl|CDD|372110
CP032698.1|AYG81358.1|3909443_3910877_+|Glutamate-decarboxylase	unknown	unknown	gnl|CDD|130848
CP032698.1|AYG81357.1|3909021_3909387_+|hypothetical-protein	unknown	unknown	gnl|CDD|376657
CP032698.1|AYG81360.1|3911996_3912533_-|hypothetical-protein	unknown	unknown	gnl|CDD|368218
CP032698.1|AYG81374.1|3926619_3928011_-|Adenine-permease-AdeQ	unknown	unknown	gnl|CDD|225161
CP032698.1|AYG81375.1|3928276_3928492_+|hypothetical-protein	unknown	unknown	gnl|CDD|378488
CP032698.1|AYG81372.1|3925247_3925703_-|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|197670
CP032698.1|AYG81365.1|3916664_3917135_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81369.1|3921990_3923001_+|General-stress-protein-69	unknown	unknown	gnl|CDD|381313
CP032698.1|AYG81362.1|3914386_3915286_-|hypothetical-protein	unknown	unknown	gnl|CDD|379262
CP032698.1|AYG81364.1|3916126_3916366_-|hypothetical-protein	unknown	unknown	gnl|CDD|377231
CP032698.1|AYG81376.1|3928621_3931039_+|putative-cation-transporting-ATPase-E	unknown	unknown	gnl|CDD|319795
CP032698.1|AYG81367.1|3919715_3920855_-|hypothetical-protein	unknown	unknown	gnl|CDD|378525
CP032698.1|AYG81363.1|3915577_3916078_+|hypothetical-protein	unknown	unknown	gnl|CDD|340413
CP032698.1|AYG81371.1|3923882_3925220_-|Enterobactin-exporter-EntS	unknown	unknown	gnl|CDD|340863
CP032698.1|AYG81368.1|3921234_3921927_+|hypothetical-protein	unknown	unknown	gnl|CDD|379419
CP032698.1|AYG81366.1|3917167_3919228_-|Inner-membrane-protein-YccS	unknown	unknown	gnl|CDD|130728
CP032698.1|AYG81361.1|3912847_3914305_-|Putative-aldehyde-dehydrogenase-YfmT	unknown	unknown	gnl|CDD|143469

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81370.1|3923197_3923791_-|RNA-2',3'-cyclic-phosphodiesterase	gnl|CDD|274058	TIGR02258, UPF0097_protein_AF_2157, 2'-5' RNA ligase. This protein family consists of bacterial and archaeal proteins with two tandem copies of Pfam domain pfam02834. Members for which activity has been measured perform a reversible, ATP-independent 2'-5'-ligation of what is presumably a non-phyiological substrate: half-tRNA splice intermediates from an intron-containing yeast tRNA. The physiological substrate(s) in prokaryotes may include small 2'-5'-link-containing oligonucleotides, perhaps with regulatory or biosynthetic roles. [Transcription, RNA processing].	4.43883e-33
CP032698.1|AYG81359.1|3911355_3911958_-|hypothetical-protein	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	6.48553e-10
CP032698.1|AYG81373.1|3925929_3926112_+|hypothetical-protein	gnl|CDD|372110	pfam12441, CopG_antitoxin, CopG antitoxin of type II toxin-antitoxin system. CopG antitoxin is a member of a type II toxin-antitoxin system family found in bacteria and archaea. Most antitoxins encoded by the relBE and parDE loci belong to the MetJ/Arc/CopG family of dimeric proteins which bind DNA through N-terminal ribbon-helix-helix (RHH) motifs. The toxin for CopG proteins falls into the family BrnT_toxin, pfam04365.	0.000682209
CP032698.1|AYG81358.1|3909443_3910877_+|Glutamate-decarboxylase	gnl|CDD|130848	TIGR01788, Glutamate_decarboxylase_alpha_GAD-alpha., glutamate decarboxylase. This model represents the pyridoxal phosphate-dependent glutamate (alpha) decarboxylase found in bacteria (low and hi-GC gram positive, proteobacteria and cyanobacteria), plants, fungi and at least one archaon (Methanosarcina). The product of the enzyme is gamma-aminobutyrate (GABA).	0
CP032698.1|AYG81357.1|3909021_3909387_+|hypothetical-protein	gnl|CDD|376657	pfam01906, YbjQ_1, Putative heavy-metal-binding. From comparative structural analysis, this family is likely to be a heavy-metal binding domain. The domain oligomerizes as a pentamer. The domain is about 100 amino acids long and is found in prokaryotes.	1.26178e-41
CP032698.1|AYG81360.1|3911996_3912533_-|hypothetical-protein	gnl|CDD|368218	pfam04978, DUF664, Protein of unknown function (DUF664). This family is commonly found in Streptomyces coelicolor and is of unknown function. These proteins contain several conserved histidines at their N-terminus that may form a metal binding site.	1.58027e-47
CP032698.1|AYG81374.1|3926619_3928011_-|Adenine-permease-AdeQ	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	1.48311e-108
CP032698.1|AYG81375.1|3928276_3928492_+|hypothetical-protein	gnl|CDD|378488	pfam10745, DUF2530, Protein of unknown function (DUF2530). This family of proteins with unknown function appears to be restricted to mycobacteria.	0.000379946
CP032698.1|AYG81372.1|3925247_3925703_-|putative-HTH-type-transcriptional-regulator	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	4.65062e-21
CP032698.1|AYG81362.1|3914386_3915286_-|hypothetical-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	1.04703e-08
CP032698.1|AYG81369.1|3921990_3923001_+|General-stress-protein-69	gnl|CDD|381313	cd19087, AKR_AKR12A1_B1_C1, AKR12A, AKR12B, AKR12C families of aldo-keto reductase (AKR). Streptomyces fradiae TylCII, Saccharopolyspora erythraea EryBII, and Streptomyces avermitilis aveBVIII are founding members of aldo-keto reductase family 12 member A1 (AKR12A1), B1 (AKR12B1), and C1(AKR12C1), respectively. TylCII acts as a NDP-hexose 2,3-enoyl reductase. EryBII is a mycarose/desosamine reductase involved in L-mycarose and D-desosamine production. aveBVIII functions as a dTDP-4-keto-6-deoxy-L-hexose-2,3-reductase.	2.42643e-161
CP032698.1|AYG81364.1|3916126_3916366_-|hypothetical-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	3.21446e-19
CP032698.1|AYG81376.1|3928621_3931039_+|putative-cation-transporting-ATPase-E	gnl|CDD|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
CP032698.1|AYG81367.1|3919715_3920855_-|hypothetical-protein	gnl|CDD|378525	pfam10979, DUF2786, Protein of unknown function (DUF2786). This family of proteins has no known function.	7.18956e-12
CP032698.1|AYG81361.1|3912847_3914305_-|Putative-aldehyde-dehydrogenase-YfmT	gnl|CDD|143469	cd07151, ALDH_HBenzADH, NADP+-dependent p-hydroxybenzaldehyde dehydrogenase-like. NADP+-dependent, p-hydroxybenzaldehyde dehydrogenase (PchA, HBenzADH) which catalyzes oxidation of p-hydroxybenzaldehyde to p-hydroxybenzoic acid and other related sequences are included in this CD.	0
CP032698.1|AYG81371.1|3923882_3925220_-|Enterobactin-exporter-EntS	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.58107e-77
CP032698.1|AYG81368.1|3921234_3921927_+|hypothetical-protein	gnl|CDD|379419	pfam14016, DUF4232, Protein of unknown function (DUF4232). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 177 and 242 amino acids in length. Many members of this family are lipoproteins.	4.33623e-15
CP032698.1|AYG81366.1|3917167_3919228_-|Inner-membrane-protein-YccS	gnl|CDD|130728	TIGR01667, Uncharacterized_protein_HI_1680, integral membrane protein, YccS/YhfK family. This model represents two clades of putative transmembrane proteins including the E. coli YccS and YhfK proteins. The YccS hypothetical equivalog (TIGR01666) is found in beta and gamma proteobacteria, while the smaller YhfK group is only found in E. coli, Salmonella and Yersinia. TMHMM on the 19 hits to this model shows a consensus of 11 transmembrane helices separated into two clusters, an N-terminal cluster of 6 and a central cluster of 5. This would indicate two non-membrane domains one on each side of the membrane.	2.45978e-20
CP032698.1|AYG81363.1|3915577_3916078_+|hypothetical-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	4.63435e-23

Protein sequences

>CP032698.1|AYG81366.1|3917167_3919228_-|Inner-membrane-protein-YccS
MSWLRALRETARSGLTVERRRLEPLVALRGATGLAIVVGVSLTLFGPSVAASSAFGAFQGAIATYQRSWRPRPVLALASGLSLAISTFLGYLVGTHSPFFLLLLAAWTFLAGLAWAVGPTVGVIASSNVAIMLVTVTLPSSLAEAAGHAAMIAFGGVVQAALVVLFPIRRWGAQRDALADALAAEADYARRLRHDPVAPFDPQPLMTARLAAAVTPREARRRPAELHGARGVAERIRPVLASLADPALGVPEEGVERDRARELLAAAATVLDAAARAVRHGEAPVIPPAAEAALATPDTGAILTGPARRAAARLIALLADVVETAQGSGTGGGAEPLLRPTLPRLVPLALRTMRDEAGRRNSPVFRHAVRVCAVATAGYLLGHVLPFGHGYWAPMASVMVMRPDFTLTYARAVARFGGTLVGVALATGIVQLTHPDTGLSAAIAVACAFLAYLLMRTGYAVLSGCVSAYVVFLLGMGGLQWTQTVPDRVFLTLIGGALAMASYALYPAWETPRLRTRLADWLAANGRYASAVVAHYADPDRGAGAVRQALLDTRAARIAWQEALDKATHEPVRHRGLSRSAAEEADHALSQLGRTAMLMEAHLPERDAVPVPAAAKLAEALSEATEQGAKAVRERRVPHWEGVEQALAAWDGEGVPDRVVRRGAGLVLHCLDDLTDALTPPNPPKP
>CP032698.1|AYG81365.1|3916664_3917135_+|hypothetical-protein
MHKHIRTAAFAAAGLSAALVLTGCGSSKSDDKPAAKSPSAEASATPTSGGTPAKSADLQGSWTATTGGKTVTMAVAGKGAALLSPHVCSGQVAENAGMTMLTLKCADGNTERTQGMATVKGDKLEVRWESGGTDSFTRGKTGSLPTALPTAGLPTP
>CP032698.1|AYG81364.1|3916126_3916366_-|hypothetical-protein
MHHAYNGMAAAELQGAAWQKSRHSNSQGSCVEFAKLPGGGVAVRNSRHPDGPALVYTRAEIEAMLLGIKDGEFDHLIAD
>CP032698.1|AYG81363.1|3915577_3916078_+|hypothetical-protein
MGTNGSTMLEPHEPLRQALPPIDPSTVAGSASCALPARYEAVGGARKFTRSTLTQWGLAECFDDVALVVSELVTNALRHALPADTPRETEVPVRLHLMRWTGRLVCAVRDPSDESPVAREGDDFGAESGRGLFLVESFADSWGWHPLSGAIHGKVVWALFRLQHAD
>CP032698.1|AYG81362.1|3914386_3915286_-|hypothetical-protein
MTAGEAWGSPRPSAVEAGGGSVVRRILLGSQLRRLRESRGITREAAGYSIRASESKISRMELGRVSFKARDVEDLLTLYGVGDESERMSLLGLAKEANIAGWWHSFGDVLPGWFQTYIGLEGAASLIRIYEVQFVHGLLQTEAYAHAVVSRGMQGAPRAEVEKRVALRLERQKALVSERAPQFHAVLDEAALRRPYGERDVMRGQLKHLIEMSEQPNITLQVMPFSFGGHAGESGAFTMLRFPESDLSDIVYLEQLTSALYLDKAEEVAQYEKAMVRLQQDSPGPEESRDLLRGLLQLS
>CP032698.1|AYG81361.1|3912847_3914305_-|Putative-aldehyde-dehydrogenase-YfmT
MSFFTDLAHQFIDGQWRTGSGSWDIIDFDPYNGEKLASITVATVEEVDEAYRAAERAQREWARTNPYTRRLVFERALRITEEREAEIIEAIVSELGGTRLKAVYEVHLAKEFLREAIQLALRPEGRILPSPVDGKENRVYRLPVGVIGVISPFNFPFLVTLKSVAPALALGNAVVIKPNQNAPVVGGGLIAKIFKDAGLPAGLLNVLVTDIAEIGDALIEHPVPKVISFAGSDRTGRHVASVAGSHFKRVILELSGNSALVVLDDADLDYAVDAAVFSRFVYQGQVCMAANRILVDRSVEEEFTGKFLAKIASLRTGDPADPATDIGPVINNFQAESLTSLVEQALAEGATALVRGRTRGNLVEPTVLTGLPADSTVLRQEIFGPVALLISFDGEEEAVRMANDSPYGLSGAVHTANVERGVRFAKRIETGMMHVNDSTIQDEPLVAFGGEKYSGLGRLNGDSTVEAFTTQKWISVQHERSPFPF
>CP032698.1|AYG81360.1|3911996_3912533_-|hypothetical-protein
MVTHVPSEARGDERGALLLFVEAQRGGVRRALIGLTEEQAASRPSAGELSLSGLLKHVAECELNWLRMAQQIPNEKQRSEANWHESFLLVGDETVEGMLAFWAEVAAQTEEFIRTVPSLDDTFPLPDAPWFPKDGQVSMRWLMLHLIEEFARHAGHADIIRESIDGKTAFELVALANG
>CP032698.1|AYG81359.1|3911355_3911958_-|hypothetical-protein
MSTIRLLVLGAVRGHGRAHGYQVRSDLEYWGAHEWSNAKPGSIYHALKHMAKQGVLLAHEVAPSTAGGPPRTEYELTEAGREEYFRLLREALSSYDQKLDALSAALGFMVDLPRAEVLSLLRDRLERLARWRGAVTEYYLAGASPQRYGHIGEIMNMWVHSAEAGAEWTRGLIGRIEGGAYVFAGEGDSPTPPLPETLRG
>CP032698.1|AYG81358.1|3909443_3910877_+|Glutamate-decarboxylase
MALHRGGNEKERHLDEKEYARLALNPFFGEADPVGSMTSAPPRHRLPDRPLAPATAYQLVHDELMLDGNSRLNLATFVTTWMEPQAGVLMAECRDKNMIDKDEYPRTAELERRCVAMLADLWHAPDPSAAVGCSTTGSSEACMLAGMALKRRWMQRNADRYPSREARPNLVMGVNVQVCWEKFCAFWEVEARQVPMEGDRFHLDPEAAAALCDENTIGVVGVLGSTFDGSYEPVAALCSALDDLQERTGLDVPVHVDGASGAMVAPFLDEDLVWDFRLPRVSSINTSGHKYGLVYPGVGWALWRTAADLPEELVFRVNYLGGDMPTFALNFSRPGAQVVAQYYTFLRLGREGYRAVQQTARDVARGLAERIEAFGDFQLLTRGDDLPVFAFTTTPEVRRYDVFDVSRRLRERGWLVPAYTFPANREDLSVLRVVCRNGFSSDLAGLLMEDLGRLLPELRQQAAPLGRDESKSTAFHH
>CP032698.1|AYG81357.1|3909021_3909387_+|hypothetical-protein
MGIEEYGGGQTPQSDVLVVTTNDVPGYTVQQVIGEVFGLTVRSRHLGSQIGAGLKSMIGGELKGLTKTLVETRNQAMERLVAQAKARGANAVLMMRFDVTEAADVGTEVCAYGTAVILART
>CP032698.1|AYG81367.1|3919715_3920855_-|hypothetical-protein
MEAVDRAFAAALYIEGDAALDTGASLLAAAPRADAELALRGREFVRRAWDRGWQPADVVRIVRRDLDEPQVRILSGLIRDELAQYERLPARWQGQLDELPSEPWRADRFSYATAVLELYRALLALPSIEPAGPAPGASGASGLGPPVHGEPKTLARIRALLAKAEATGFPEEAEALTTKAQELMARHSVDDALLAGRGPGGEVPGACRIGVDAPYETAKAILLDAVASANHCRAVWNSALGFTTVVGFEADLEAVELLYTSLLVQGTTAMAKAEAVQRAGGRRRTKTFRQSFLLAYAARLGDLLPSAARGVEESFGGEVLPVLATRAVAVAGRAEEMFPRTVATRVRGVSDESGWRDGRAAADRAHHSRARGVCPPTRP
>CP032698.1|AYG81368.1|3921234_3921927_+|hypothetical-protein
MLRLRTAPLAATVALTAGLTMTLALTLTACGGDGGSSRVATDSPTGITPPETTGTGPGPGTPGTSGGRTMAPSGGSTGGTDAGPGTDSGAAGARCPTSQLGFAVAPGSGAQTRGSQGVITIELTNKGAKSCAMKGYPGVDLVGGSTKWSLPRGTSETPKTVTVRPGATTTFTLFYLPFHQGDGKEFKPRSLVITPPNETHPHTLPWEFSSVLLQDGATRPGTYIGPVGSK
>CP032698.1|AYG81369.1|3921990_3923001_+|General-stress-protein-69
MKYTQLGRTGLQVSRLVLGTMNFGSETDEAGSHVLMDAALDAGINFFDTANIYGVAEDKGLTEKILGSWFGRGGDRRDKVVLATKMYGDMTPGKPWSSAAWPNHDRLSALNIRRSVEASLQRLNTDYIDVYQFHHVDRATPFEEIWQAIDVLITQGKILYAGSSNFPGYKIAQANEVADRTGRLGLVSEQCLYNLAERRAEMEVIPAAQEYGLGVIPWSPLHQGLLGGALRKEREGTGSRTTKSGRSAAGLADPAVRAKVQAYEDLLAKHDLDPGEVALAWLLTRPGVTGPIVGPRTPAHLESALRALELELSEELLGALDEIFPGPGSAPEAFAW
>CP032698.1|AYG81370.1|3923197_3923791_-|RNA-2',3'-cyclic-phosphodiesterase
MPILLNCSHAPLRRRPSPERAVDELGRAVRELAALPGADGLRWTGREGWHLTLAFLGEVDEALLDELRERLRRAAHRTDPFTLRLHGGGRFDGRALWAGVAGGLDELRLLAERADAAARRSGVPMDQHRRYVPHLTLARSRTPMDLRPYVTELAAFEGSPWPVAELALIRSSLPRDGVPGERPRYEAVARWPLGAGG
>CP032698.1|AYG81371.1|3923882_3925220_-|Enterobactin-exporter-EntS
MSTGSGAHSAPAPNPTYNKRGGGTFSSLAVRNYRLFFSGAIVSNIGTWMARITQDWLVLTITGSSVAVGITTAMQFLPMLLFGLYGGVIADRFAKRNILFVTQAAMGLGGLFLAVMTLSGHVQVWHVYLTAFFTGLVTVVDNPTRQSFVSEMVGPDRVRNAVSLNSANFQSARLVGPAVAGVVMAAVGPGWAFLANGLSFTAPLIMLSLMRTKELQPTRLTPRGKGQLREGLAYVSERPELIWPIVLVGFVGTFGFNFPIWLSAFASDVFHGDSGLYGLFNSLMAIGSLVGALLAARRATTRLRMLVLAAGLFAVLELVAATSPDLGVFMALLIPVGILGLTVNVTANASVQMATDPEMRGRVMSLFMMVFTGGTPLGGPLFGWLADVYGVRVSLALGGVICGVAAIGVGLMLARAANLRLKVDVRPGHRHLAFVPRNPALVAAA
>CP032698.1|AYG81372.1|3925247_3925703_-|putative-HTH-type-transcriptional-regulator
MLKNMSDLSHGTGDNAAAVNSLRSAVMRLGRRLKHQRVDESLSPTEMSVLGTLARCGSATPGELARKEHVQPPSMTRIVALLEAKGLVRLEPHPDDRRQKVVSQTAEAEAMLEESRRKRNAWLAALAEGLDEDEWAKLRAAAPVLEKLAHL
>CP032698.1|AYG81373.1|3925929_3926112_+|hypothetical-protein
MGTSVLSLRIDGELLERLKHHAARRGMSVQDYVVRTLMRDDFDERFKAAVDETERFYGAA
>CP032698.1|AYG81374.1|3926619_3928011_-|Adenine-permease-AdeQ
MNGLDRYFKISERGSTLAREVRGGFATFFAMAYIIVLNPIILGSAKDMYGHQLDSGQLVTATVLTAAFTTLLMGVIGNVPIALAAGLGVNTVVALQLAPRMSWPDAMGMVVLAGFVVMLLVATGLRERVMNAVPLGLRKGIAIGIGLFIMLIGLVDSGFVSRMPDAAHTTVPLQLGGNGHLLGWPVLIFVLGVLLTLALMVRKVPGAILISIVAMTVLAMIINAVATVPSWGLTTPKWPGNPVDAPDFGLVGQVSLFGGFSKVGFLTGVLFVFTVLLSCFFDAMGTIMGISDEAGLTDEKGYMPGMNRVLFVDGIAVAAGGASSSSATTCFVESTAGVGEGARTGLANVVTGGLFTVALFLTPLATMVPSQAATPALLAVGFLILSGSIREIDWADWTIAIPAFVTMLMMPFTYSITNGIGMGFVSFTVLRVVAGRGREVPIAMYVVSAVFAFYYVMPALGLT
>CP032698.1|AYG81375.1|3928276_3928492_+|hypothetical-protein
MVATITGGTILWFVLFLVQLPFYGWFDAHGHLWWVWTCLAGGGLGLIGIWYVRGRDAALKRHAAQQEAGAE
>CP032698.1|AYG81376.1|3928621_3931039_+|putative-cation-transporting-ATPase-E
MTQRANIDAGAELDPVHPMSPPEPARRAGGLTAAEVAERVARGEVNDVPVRSSRSTAEIVRGNVFTRFNAIIGVLWAIMLVVAPIQDSLFGFVIIANTGIGIIQEMRAKKTLDGLAVIGEAKPTVRRDGRAVEISTSEIVLGDVIELGPGDKVVVDGEAVEADGLEVDESLLTGEADPVLKKPGDTMMSGAFVVAGGGAFTATKVGREAYAAQLAEEASRFTLVHSELRSGISTILKYVTWMMIPTALGLVLSQLVVKDNDVKDSIARTVGGIVPMIPEGLVLLTSVAFAIGVIRLGRKQCLVQELPAIEGLARVDVVCLDKTGTLTEGGMDVTELRPLNGADEAYVRTVLGALGESDPRPNASLQAIIDAYPDSEAWRCTESLPFSSARKYSGAAFSEGDGENSTWLLGAPDVLLKAGDPALSEIDALNEQGLRVLLLARSSRELDDPAIASDAEPTALVVLEQRLRPDASDTLRYFDEQNVRAKVISGDNAVSVGAVAGKLGLPGAADTVDARQLPAEQGEMADVLDSNSVFGRVTPQQKRDMVAALQSRGHTVAMTGDGVNDVLALKDADIGVSMGSGSEATRAVAQIVLLNNSFSTLPSVVAEGRRVIGNITRVATLFLTKTVYSVLLAVLVVCFQVEYPFLPRHLTLLSTFTIGIPAFFLALAPNKERAKPHFVRRVMRYAIPSGVIAAVATFVTYMIARAYYTGSGALDAETSATTLTLFLVSMWVLAIIARPYTWWRIALVVSMAVAFLLVLAVPWLQHFFALKLVGVVLPWTAVGVAVVASAVLELTWRHVTHRWPD

Crispr_ID: CP032698_31

• CRISPR_ID: CP032698_31
• CRISPR_location: 3951755-3951854
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_31

Consensus_repeat	Method
CCCCGGGGCTCCGCCCCAGACCCCG	CRISPRCasFinder

spacers of CP032698_31

>31.1|3951780|50|CP032698|CRISPRCasFinder
GCGCGCTTGCCCACCCACCCGCCCGTGCAGCGGGTTGGTTGGTTCCGGTC

CRISPR arrays and Neighbor proteins around CP032698_31

CRISPR arrays

The CRISPR arrays of CP032698_31

>merge|CP032698|31|3951755-3951854|CRISPRCasFinder
CCCCGGGGCTCCGCCCCAGACCCCGGCGCGCTTGCCCACCCACCCGCCCGTGCAGCGGGTTGGTTGGTTCCGGTCCCCTGGGGCTCCGCCCCAGACCCCG

>CP032698|31|24|3951755-3951854|CRISPRCasFinder
CCCCGGGGCTCCGCCCCAGACCCCG	GCGCGCTTGCCCACCCACCCGCCCGTGCAGCGGGTTGGTTGGTTCCGGTC
CCCTGGGGCTCCGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81387.1|3943013_3945563_+|hypothetical-protein	unknown	unknown	gnl|CDD|379300
CP032698.1|AYG81384.1|3940367_3940688_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81400.1|3958047_3960309_+|Cation-transporting-P-type-ATPase-A	unknown	unknown	gnl|CDD|319783
CP032698.1|AYG81390.1|3947498_3949151_+|hypothetical-protein	unknown	unknown	gnl|CDD|223989
CP032698.1|AYG81399.1|3956923_3957838_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81398.1|3956168_3956858_-|Copper-homeostasis-protein-CutC	unknown	unknown	gnl|CDD|225684
CP032698.1|AYG81394.1|3952158_3954225_+|DNA-helicase-IV	unknown	unknown	gnl|CDD|226482
CP032698.1|AYG81397.1|3955627_3956107_+|hypothetical-protein	unknown	unknown	gnl|CDD|340413
CP032698.1|AYG81392.1|3950363_3950570_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81393.1|3950852_3951752_+|putative-ECF-RNA-polymerase-sigma-factor-SigI	unknown	unknown	gnl|CDD|236600
CP032698.1|AYG81386.1|3941725_3942829_-|hypothetical-protein	unknown	unknown	gnl|CDD|237171
CP032698.1|AYG81389.1|3947045_3947297_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81396.1|3954587_3955469_-|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG81403.1|3962545_3963061_+|hypothetical-protein	unknown	unknown	gnl|CDD|224584
CP032698.1|AYG81388.1|3945819_3947004_-|hypothetical-protein	unknown	unknown	gnl|CDD|259798
CP032698.1|AYG81391.1|3949108_3950299_-|Polyprenol-phosphate-mannose-dependent-alpha-(1-2)-phosphatidylinositol-mannoside-mannosyltransferase	unknown	unknown	gnl|CDD|172015
CP032698.1|AYG81395.1|3954219_3954591_-|hypothetical-protein	unknown	unknown	gnl|CDD|377231
CP032698.1|AYG81402.1|3961800_3962499_+|hypothetical-protein	unknown	unknown	gnl|CDD|226789
CP032698.1|AYG81385.1|3940770_3941394_-|Phosphoglycolate-phosphatase	unknown	unknown	gnl|CDD|223620
CP032698.1|AYG81401.1|3960425_3961304_-|putative-ECF-RNA-polymerase-sigma-factor-SigI	unknown	unknown	gnl|CDD|236600

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81387.1|3943013_3945563_+|hypothetical-protein	gnl|CDD|379300	pfam13625, Helicase_C_3, Helicase conserved C-terminal domain. This domain family is found in a wide variety of helicases and helicase-related proteins.	2.48527e-39
CP032698.1|AYG81400.1|3958047_3960309_+|Cation-transporting-P-type-ATPase-A	gnl|CDD|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
CP032698.1|AYG81388.1|3945819_3947004_-|hypothetical-protein	gnl|CDD|259798	cd03399, SPFH_flotillin, Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. The flotillin (reggie) like proteins are lipid raft-associated. Individual proteins of this SPFH family may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. In addition, microdomains formed from flotillin proteins may be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and interact with a variety of proteins. They may play a role in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease and in cancer invasion, and metastasis.	5.37907e-43
CP032698.1|AYG81398.1|3956168_3956858_-|Copper-homeostasis-protein-CutC	gnl|CDD|225684	COG3142, CutC, Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism].	1.15492e-25
CP032698.1|AYG81394.1|3952158_3954225_+|DNA-helicase-IV	gnl|CDD|226482	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only].	1.34172e-64
CP032698.1|AYG81397.1|3955627_3956107_+|hypothetical-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	7.23337e-16
CP032698.1|AYG81395.1|3954219_3954591_-|hypothetical-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.48158e-17
CP032698.1|AYG81393.1|3950852_3951752_+|putative-ECF-RNA-polymerase-sigma-factor-SigI	gnl|CDD|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	3.26644e-78
CP032698.1|AYG81386.1|3941725_3942829_-|hypothetical-protein	gnl|CDD|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0.00142983
CP032698.1|AYG81396.1|3954587_3955469_-|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.7426e-07
CP032698.1|AYG81403.1|3962545_3963061_+|hypothetical-protein	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.74684e-24
CP032698.1|AYG81390.1|3947498_3949151_+|hypothetical-protein	gnl|CDD|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	3.01254e-107
CP032698.1|AYG81391.1|3949108_3950299_-|Polyprenol-phosphate-mannose-dependent-alpha-(1-2)-phosphatidylinositol-mannoside-mannosyltransferase	gnl|CDD|172015	PRK13375, pimE, mannosyltransferase; Provisional.	3.56774e-51
CP032698.1|AYG81402.1|3961800_3962499_+|hypothetical-protein	gnl|CDD|226789	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown].	7.30797e-47
CP032698.1|AYG81385.1|3940770_3941394_-|Phosphoglycolate-phosphatase	gnl|CDD|223620	COG0546, Gph, Predicted phosphatases [General function prediction only].	5.70799e-24
CP032698.1|AYG81401.1|3960425_3961304_-|putative-ECF-RNA-polymerase-sigma-factor-SigI	gnl|CDD|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	3.74707e-85

Protein sequences

>CP032698.1|AYG81393.1|3950852_3951752_+|putative-ECF-RNA-polymerase-sigma-factor-SigI
MVDDEYLAQRFEEHRGHLRAVAYRMLGSLSEAEDAVQEGWLRASRADSGAVDNLGGWLTTIVARICLNMLRARGTRREAALDVGEYEYVHVPDPVLGPVDGADPEQEVLLADSVGLALMVVLETLAPAERLAFVLHDMFAVPFEDIAPIVDKTPAATRQLASRARRRVQGRVPSPSPDRARQREVVEAFISAARGGDFEALLALLDPDVVLRADAGALPTTKLVRGARAVAEQANSFRKLAAFNRLVLVNGAPGILAVVGGRVVSVLAFTLGEDARITELNILADPTRLHPLNPLGLTP
>CP032698.1|AYG81392.1|3950363_3950570_-|hypothetical-protein
MSTTTCTPAPSARPGTPRGATASGAAPHRTHKIGNAVRAAKVLAGAAFSVVVMGEFAEEAGVRRRHQG
>CP032698.1|AYG81391.1|3949108_3950299_-|Polyprenol-phosphate-mannose-dependent-alpha-(1-2)-phosphatidylinositol-mannoside-mannosyltransferase
MTVTVRTPRAAATTRAIVLLGLSLAALTVLCAALRIPMADAQVYRAEGAAVAHGGPLYGFTVTPWHLPATYPPFAALLFLPTAFVPLSALKAAFCGANVALLALLVVLSCRFARIEVRAAHVLAATALALWLEPVFQTLIFGQVNLALVCLVLWDLSRPAGAFAKGFAVGLAAGIKITPLFFVLHLLVRGRVREALTALAGFITTVLVAALVLPYASVEFFTRRLFETGRVGKAWIVDNQSLQGLLARLLHTPAPGMVWAAGALVVGAAGLWIARRAEERHALLVSSFTALLISPISWSHHWVWCVPLIALAAGEGRARAAVVLAVVFTARTLWLVPHAGELDLQLPLWQQPLASPYALVGLAVLGWATRRSGRRAAPVEPDAQLPARSSSASMIR
>CP032698.1|AYG81390.1|3947498_3949151_+|hypothetical-protein
MPQVTGPLIVQSDKTLLLEVDHEQADACRRAIAPFAELERAPEHIHTYRLTPLGLWNARAAGHDAEQVVDALVEYSRYPVPHALLVDIAETMDRYGRLTLSKHPTHGLVLTSTDRPVLEEILRSKKVAPLVGARIDADTVAVHPSERGQIKQTLLKLGWPAEDLAGYVDGEAHPIELAEDGWALRPYQRQAVEGFWHGGSGVVVLPCGAGKTLVGAGAMAEAKATTLILVTNTVSARQWKHELVKRTSLTEDEIGEYSGTKKEIRPITIATYQVLTTRRKGVYAHLELFDSRDWGLIVYDEVHLLPAPVFKFTADLQARRRLGLTATLVREDGRESDVFSLIGPKRFDAPWKEIEAQGYIAPADCVEVRVNLTDSERLAYATAETEEKYRFCATTATKRKVTEALVRKFAGQQILVIGQYIDQLDELGEHLNAPVIKGETTNAQREKLFGAFREGEISVLVVSKVANFSIDLPEATVAIQVSGTFGSRQEEAQRLGRVLRPKADGHQAHFYSVVARDTIDQDFAAHRQRFLAEQGYAYRIMDADELLAGN
>CP032698.1|AYG81389.1|3947045_3947297_-|hypothetical-protein
MEQDEAVIGCPGVLHVATRGTAGPGEVVVSVRGGTEAFLAWSQEPLPKGATVLVIGSRGTRQVDVIEWADPLDASGGLSADAG
>CP032698.1|AYG81388.1|3945819_3947004_-|hypothetical-protein
MFGYRVPAPDEAMLISGGRRGLGGAPFRVVTGHGKFVLPVFRKTRFLTLSMCEAEVTETCVTKQGIALHVRAVIAFKVGNDTESIVNAGQRFLSDQDQMSVLTGRIFAGHLRSIIGSMTVEEIVTERQKLAAEVLETSKTEMAKIGLIVDSLQIQSIDDGDVGYIDAMSAPHKAAIHRAAQIAQAQATQAAVEAEQVAARNQAEYARQTAVVKAEYSAEVDRAQAQAAQAGPLAQAHAQQEVLAAQTELAERAAELRQQQLVAEIVKPAEAEAERIKVLAIAEAERMKIQAEAAASYDRVALDRMLIDQLPQIVKEAAGGLAGANVNVLNGADGLGEIAAGLVGQGLTILDSVRQNLGGSDRSEGKGGQLSLPGLSSRSGSGGAAKGDGPVGLD
>CP032698.1|AYG81387.1|3943013_3945563_+|hypothetical-protein
MGTGERNQEAHVSEGSTGATSTAAAGATSRGASGATSRGAAAAAPRTLAESLRARSDASLAALLRIRPDLLNPVPSDLTQLATRAGTRASVVRALERLDTFALQTAQVLAVAPEPAPYEAVRALLVGDDGDAAVEAALPGALAALREQALVWGGDDRLRLVRTARELLAPSPHHPSPTGLGPTVAEATAGMSPGRVQEILQAAGLPATHDPVSAVTALTSLFTDRARMAELLDSAPSEALTVLDRLVWGPPYGEVSADPPPPVRWLRDHGLLLPASARTVVLPREVALHLRAGRAHRTTEPVPPAVAPLREYRPQVVDAAAAGQAFTALTTVEDLLAEWNEGGPAVLRAGGLSVRDLKRTATALDTSEQTAAFWLELAYAAGLLASDGEADERYAPTPEYDAWLELPPAERWARLAMAWLAATRTAGLVGEQDAKGRTLSALGPDLDRSPAPEVRHRVLTLLTTLPEATSAEPGSLLARLRWEHPARSGPDDLRPRLAQWTLSEAELLGVTGRGALTTHGRTLLAPATGAAEREALGLLAAKALAPHLPEPVDHVLLQADLTAVAPGPLRRPLAAMLGVLADIESKGGATVYRFTAGSVRRALDAGQTAADLQAFLTEHSRTPVPQPLSYLIDDVARRHGHLRVGAASAYVRCDDEAMLGEILADKRSQPLRLRRLAPTVLATTAEPAALLDGLRSMGYAPAAESAEGDVLITRADARRTPRRAAPAPVPDGPPRPDETLLDAAVRAIRAGDTAATVVRKDQPSAAAGAPGALPRTSSAETLATVQAAAMTGSAVWIGYVNAEGAASQRVIAPVRVEGGFVTGYDHTADEVRTYPLHRITGVAELPDPA
>CP032698.1|AYG81386.1|3941725_3942829_-|hypothetical-protein
MGIESDQLVYDYLSRVGDLAQQRQVPSGDRMRLVSSLRNEIDKQRAKYATETPATVRRVLGRFGTPEEVVDALASGTAPGFGSGAPAPRPAPDPAVPVQRDRPFPGRGKRVPRPRPRRSAETPPPAASSLPSPPHLAGMDELGRQGDEPDWWRIGPGGSPGAPGLLGGDSIAGFVGGVEIPEILRPPVDEDEDELGEGKDAGGRRRGEADAEGGDEDGVGGVAEDEDLVEVVPSGRRLPRLRRRRRGSAEAGARPAVANPFLLLAAALLATGALFGLWVALGAGWLLAYASRRLTRAESKWAVLGMPGLTLLGGLVWLWGRQDGRWGEPIAQGEMGAAMTDMWPWLVRVAAVASAGFLVWRARRVGQ
>CP032698.1|AYG81385.1|3940770_3941394_-|Phosphoglycolate-phosphatase
MPYDAPTVGFDLDMTLIDSRPGIRAVYQELSATTGTYIDADQAVGRLGPPLDWELRHWFAEEHIPAMVLKYREIYPTRAILPTPALPGAAAAVRAVQELGGRAVVVTAKNAPQAQLHLDHLGITPDAVIGGLWAEAKATALREHGAAVYVGDHLGDVLGARAAGALSVAVPTGPIGAVELREAGADVVLDDLTSFPAWLKGYAAQRA
>CP032698.1|AYG81384.1|3940367_3940688_+|hypothetical-protein
MVLGLLTRRPGLSLRAGNYPGGVSTETQAKADRSAPTTGDRLVRIGVVVFFVGALATLVTVAPLFLHIDPFPSFAYLVCMLMGAGFLIAGAGVLLTIAEERRGARA
>CP032698.1|AYG81394.1|3952158_3954225_+|DNA-helicase-IV
MPAHAPTPNPLDHERTHLAHSRAALRAMREDVQALDIKDVTANWVNAAVLQRQIDDRIKALADLSHTPLFFGRLDYLHAPGADLAEGAGGERFYIGRRHVHDADGDPMVIDWRAPVSQPFYRASKKDPLDVSLRRRFGYTGGELTAYEDEHLMDATETARTSKLLQAEIERPRVGPMRDIVATIQPEQDEIVRSGLSGSVCVQGGPGTGKTAVGLHRVAYLLYAHRDRLARTGTLVIGPNKSFLHYIEQVLPALGELEVKQATVDDLVASTGVEVRGTDPAEAAVIKGDARMAEVLRRAVWSHVTTPSEPLVVVRGSRRWRVPAYELATIVEELRDRDIRYGAAREALPQRIAHTVLVRMEQAGEAPDDRVQDAVARNTAVKAAVKAIWPPVDPAKLVLRLLNEPAFLATHAEGILTDDEQKAILAPKPARSVKAAKWSAADAVLIDETNDLVARTPSLGHVVLDEAQDLSPMQYRAVGRRCTTGSATVLGDLAQGTTPWATASWAEALRHLGKGDAVVEELTAGFRVPREVIAYASKLLPSISPGLAPVESVRETPGSLDVRAASTPAELDAAVVAACEESLAHEGSIGLIAADARIPVLAKALEAAGLAHLDPGEETTATSRLTLVPASLAKGLEYDYVVLDEPTAVVDGEPDERTGLRRLYVALTRAVSGLTIVHASPLPPQLAL
>CP032698.1|AYG81395.1|3954219_3954591_-|hypothetical-protein
MSTTELGWFKSSYSSGSGDDCVEVALDWRKSTYSSGSGDSCVEVAECWSKSSYSSAEGDSCVEVSACWSKSSYSSGDGDSCVEVAATPAVIHVRDSKDKAGPQLTLSPGAWGEFVAYAGVGPL
>CP032698.1|AYG81396.1|3954587_3955469_-|hypothetical-protein
MPWDHEDHDDHEDQAGLDDHEGRDGEPEASDSLRTFGAVVQALREHAGLSRAQLGALVGYSKHTVASVELGRRMPDPAFIERAERALGNTGALTAAARHLSRQPGLASWFRRWARLERTAISLYTYESRLIPGLLQTEAYALALFRAQLPPLADAQIDANMVARLKRQRLLTERPNTAYSFIVDEHVFARRTGGPDVTRELIDYVLERTAARNVELQILPAGLGVHAGLAGPIRLAETPAHRWFGYCEGQESGIFVSDPKLISTLHMRYAKLRSQALTPEQSVGRLELLRGAP
>CP032698.1|AYG81397.1|3955627_3956107_+|hypothetical-protein
MHLDMEPRAEQLPATVCAFRKRFASTRRAAGLARRLAQGQLAAWGIAPESEASRTAALLVAELAANAVLHAYVSGRGFEVGVALREDGVLRIEVTDTRADKALPVVASAPAADCESGRGLLLVQAFADHWGTVEGPTPLKTVWAQLALPEGEFIRVLRP
>CP032698.1|AYG81398.1|3956168_3956858_-|Copper-homeostasis-protein-CutC
MSNRALLEVIALDAQDAVAAQAGGADRLELVTDMAADGLTPSRETFAAIRAAVDIPLRVMLRAHDGFAAGDVDALLRDAEALRAEGADEFVLGFLDETGGPDMAALRALAPVLDGCRWTFHRAVDRAASRDALRKELSGLAGLDTYLTAGSPLGVDDGLPVLLAEAARHGEPGYEPRILVGGGLQLTHLPVLRDAGIDAVHIGGASRPGGWSEPVSPAAVAEWRAALDA
>CP032698.1|AYG81399.1|3956923_3957838_-|hypothetical-protein
MKFVMGTGLKITAFAAALAATFGTAYGVGKGVDPIVAQPAGHAAHGEPTAKAGHGGHEEQDGAAELPGGLQIAEGGYALDLRTPRLEAGRAAEIRFAVTGHDGRPVTAFKSEHGKELHLVVASDDLAVYRHLHPVRAADGTWSVPAELPEAGGYRVFADFTPGDTKDAKNLVLGADLAVSGAYAPKELPAPTATAPVEDGYTVSLAGDLTPGRTAELKLSVTKEGRPVTDLEPYLGAYGHLVALRAGDLAYLHVHPNEGGPGPVVSFGATVPSAGTYRLFLDFQHGGKVRTAGFTVAAGGHLAA
>CP032698.1|AYG81400.1|3958047_3960309_+|Cation-transporting-P-type-ATPase-A
MTTTTTPGAADVELVIGGMTCASCAARIEKKLNRMDGVEATVNYATEKAKVTFREDVSVADLIATVEATGYTAKEPAPVRTESGPAEGEREEAADELRPLRQRLLTAAVLAIPVIAMSMVPALQFEYWQWLSLTLTAPVVTYAAWPFHRAAWTNARHGAATMDTLISVGTSAAFLWSLWALFFGTAGTPGMTHPFELTIGRSDGAGNIYLEAAAGVTAFILAGRYFEARSKRKAGAALRALLELGAKDVTVLRADGRELTVPTDELKVGDRFLVRPGEKIATDGTVVEGSSAVDASMLTGESVPVEVAPGDAVTGATLNAGGRLVVEASRVGADTQLARMAKLVEDAQNGKAAAQRLADKISAVFVPVVIGLALATLGFWLGNGSGLTAAFTAAVSVLIIACPCALGLATPTALMVGTGRGAQLGILIKGPEVLETTRKVDTIVLDKTGTVTTGRMTLLAVHTTDTTDEAEVLRLAGALEHSSEHPIARAVADGAAAKVGPLPTPEDFANIAGLGVQGVVDGHAVLVGRENLLGDWAMELTPALKRAKEEAEAAGRTAIAVAWDGEARAVLEVADAIKETSPEAIRRLRALGLTPILLTGDNRAVAEAVAAEVGIDTVYAEVMPQDKVDVVKSLQAEGRSVAMVGDGVNDAAALAQADLGLAMGTGTDAAIEAGDLTLVRGDLRAAADAIRLSRKTLGTIKSNLFWAFAYNVAALPLAAAGLLNPMIAGAAMAFSSVFVVGNSLRLRGFQATV
>CP032698.1|AYG81401.1|3960425_3961304_-|putative-ECF-RNA-polymerase-sigma-factor-SigI
MHADEYLAERFEGHRGHLRAVAYRMLGSLHEADDAVQEAWLRLSRSDTGTVASLGGWLTTVVGRVCLDMLRARASRREDPLGLHVPDPIVTGADGAGPQDEVLLADSVGLALLVVLETLSPAERLSFVLHDLFAVPFDEIAPIVGRTPAAARQLASRARRRVRGGAPASDMDPAGRREVVEAFMAAAREGDFDALVAVLDPDVVARSDGGELRPGGVLRGARAVAGGAVFGARLAEFTILVLVNGSPGLVSLTEGRPLSVMAFTIAAGRITTIDILADPERLGTLDLTVLTT
>CP032698.1|AYG81402.1|3961800_3962499_+|hypothetical-protein
MRASTEWLGARPATLGRMPHPNDLLLRWHQAILATRSPANSPVDPTPYGENLLARWAEPQRHYHDTTHLTAVLDHIDVLERYADQPDLVRLAAWFHDAVYLPDRSENEERSARLAERALPEAGLSREDTAEVARLVRLTVTHAPEEGDANGAVLCDADLAILAAAPDAYAAYAAAVREEYAFVPDEAFRSGRGEVLAQLLALPALFRTPHGVRAWEGPARENLEAELTLLTA
>CP032698.1|AYG81403.1|3962545_3963061_+|hypothetical-protein
MLPVTVQADRIALHELTRASAAALQDGGSGGWRWAPGGPHEGSRFAAAKMLAGIETGRHRTGWGAYVIVRAEDGRAIGGIGFHGPPEDGRVEIGYDLAESARGQGYATESLAVLTAWALAQPDVETVYATTDEDNTASQRVLERAGFRRVGDTPRTIGGRRRQHVFEHTGA

Crispr_ID: CP032698_32

• CRISPR_ID: CP032698_32
• CRISPR_location: 3961391-3961487
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_32

Consensus_repeat	Method
CCCCTGGGGCTCCGCCCCAGACCCC	CRISPRCasFinder

spacers of CP032698_32

>32.1|3961416|47|CP032698|CRISPRCasFinder
ACGGGTTTGCCCACCCACCCGCCCGTGCAGGGGGCTGGAGGGTTCGG

CRISPR arrays and Neighbor proteins around CP032698_32

CRISPR arrays

The CRISPR arrays of CP032698_32

>merge|CP032698|32|3961391-3961487|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCACGGGTTTGCCCACCCACCCGCCCGTGCAGGGGGCTGGAGGGTTCGGCCCCTGGGGCTCCGCCCCAGACCCC

>CP032698|32|25|3961391-3961487|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCC	ACGGGTTTGCCCACCCACCCGCCCGTGCAGGGGGCTGGAGGGTTCGG
CCCCTGGGGCTCCGCCCCAGACCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81400.1|3958047_3960309_+|Cation-transporting-P-type-ATPase-A	unknown	unknown	gnl|CDD|319783
CP032698.1|AYG81402.1|3961800_3962499_+|hypothetical-protein	unknown	unknown	gnl|CDD|226789
CP032698.1|AYG81411.1|3969087_3970950_+|hypothetical-protein	unknown	unknown	gnl|CDD|283837
CP032698.1|AYG81399.1|3956923_3957838_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81398.1|3956168_3956858_-|Copper-homeostasis-protein-CutC	unknown	unknown	gnl|CDD|225684
CP032698.1|AYG81394.1|3952158_3954225_+|DNA-helicase-IV	unknown	unknown	gnl|CDD|226482
CP032698.1|AYG81397.1|3955627_3956107_+|hypothetical-protein	unknown	unknown	gnl|CDD|340413
CP032698.1|AYG81409.1|3967511_3968441_+|N-acetylmuramic-acid-6-phosphate-etherase	unknown	unknown	gnl|CDD|235467
CP032698.1|AYG81395.1|3954219_3954591_-|hypothetical-protein	unknown	unknown	gnl|CDD|377231
CP032698.1|AYG81393.1|3950852_3951752_+|putative-ECF-RNA-polymerase-sigma-factor-SigI	unknown	unknown	gnl|CDD|236600
CP032698.1|AYG81407.1|3965997_3966384_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81405.1|3965173_3965377_-|Cold-shock-protein-ScoF	unknown	unknown	gnl|CDD|224197
CP032698.1|AYG81396.1|3954587_3955469_-|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG81403.1|3962545_3963061_+|hypothetical-protein	unknown	unknown	gnl|CDD|224584
CP032698.1|AYG81410.1|3968654_3969083_+|hypothetical-protein	unknown	unknown	gnl|CDD|182130
CP032698.1|AYG81404.1|3963631_3964927_+|Inner-membrane-transport-protein-YdhP	unknown	unknown	gnl|CDD|225371
CP032698.1|AYG81392.1|3950363_3950570_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81406.1|3965734_3966001_-|hypothetical-protein	unknown	unknown	gnl|CDD|379076
CP032698.1|AYG81408.1|3966540_3967446_+|HTH-type-transcriptional-regulator-MurR	unknown	unknown	gnl|CDD|224651
CP032698.1|AYG81401.1|3960425_3961304_-|putative-ECF-RNA-polymerase-sigma-factor-SigI	unknown	unknown	gnl|CDD|236600

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81400.1|3958047_3960309_+|Cation-transporting-P-type-ATPase-A	gnl|CDD|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
CP032698.1|AYG81402.1|3961800_3962499_+|hypothetical-protein	gnl|CDD|226789	COG4339, COG4339, Uncharacterized protein conserved in bacteria [Function unknown].	7.30797e-47
CP032698.1|AYG81398.1|3956168_3956858_-|Copper-homeostasis-protein-CutC	gnl|CDD|225684	COG3142, CutC, Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism].	1.15492e-25
CP032698.1|AYG81394.1|3952158_3954225_+|DNA-helicase-IV	gnl|CDD|226482	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only].	1.34172e-64
CP032698.1|AYG81397.1|3955627_3956107_+|hypothetical-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	7.23337e-16
CP032698.1|AYG81409.1|3967511_3968441_+|N-acetylmuramic-acid-6-phosphate-etherase	gnl|CDD|235467	PRK05441, murQ, N-acetylmuramic acid-6-phosphate etherase; Reviewed.	2.78472e-156
CP032698.1|AYG81395.1|3954219_3954591_-|hypothetical-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.48158e-17
CP032698.1|AYG81393.1|3950852_3951752_+|putative-ECF-RNA-polymerase-sigma-factor-SigI	gnl|CDD|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	3.26644e-78
CP032698.1|AYG81411.1|3969087_3970950_+|hypothetical-protein	gnl|CDD|283837	pfam06259, Abhydrolase_8, Alpha/beta hydrolase. Members of this family are predicted to have an alpha/beta hydrolase fold. They contain a predicted Ser-His-Asp catalytic triad, in which the serine is likely to act as a nucleophile.	2.00052e-26
CP032698.1|AYG81405.1|3965173_3965377_-|Cold-shock-protein-ScoF	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	5.41746e-35
CP032698.1|AYG81396.1|3954587_3955469_-|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.7426e-07
CP032698.1|AYG81403.1|3962545_3963061_+|hypothetical-protein	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.74684e-24
CP032698.1|AYG81404.1|3963631_3964927_+|Inner-membrane-transport-protein-YdhP	gnl|CDD|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	2.45996e-81
CP032698.1|AYG81410.1|3968654_3969083_+|hypothetical-protein	gnl|CDD|182130	PRK09880, PRK09880, L-idonate 5-dehydrogenase; Provisional.	0.00559516
CP032698.1|AYG81406.1|3965734_3966001_-|hypothetical-protein	gnl|CDD|379076	pfam13223, DUF4031, Protein of unknown function (DUF4031). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and viruses. Proteins in this family are typically between 91 and 130 amino acids in length. There is a conserved HYD sequence motif.	9.63145e-35
CP032698.1|AYG81408.1|3966540_3967446_+|HTH-type-transcriptional-regulator-MurR	gnl|CDD|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	4.54202e-68
CP032698.1|AYG81401.1|3960425_3961304_-|putative-ECF-RNA-polymerase-sigma-factor-SigI	gnl|CDD|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	3.74707e-85

Protein sequences

>CP032698.1|AYG81401.1|3960425_3961304_-|putative-ECF-RNA-polymerase-sigma-factor-SigI
MHADEYLAERFEGHRGHLRAVAYRMLGSLHEADDAVQEAWLRLSRSDTGTVASLGGWLTTVVGRVCLDMLRARASRREDPLGLHVPDPIVTGADGAGPQDEVLLADSVGLALLVVLETLSPAERLSFVLHDLFAVPFDEIAPIVGRTPAAARQLASRARRRVRGGAPASDMDPAGRREVVEAFMAAAREGDFDALVAVLDPDVVARSDGGELRPGGVLRGARAVAGGAVFGARLAEFTILVLVNGSPGLVSLTEGRPLSVMAFTIAAGRITTIDILADPERLGTLDLTVLTT
>CP032698.1|AYG81400.1|3958047_3960309_+|Cation-transporting-P-type-ATPase-A
MTTTTTPGAADVELVIGGMTCASCAARIEKKLNRMDGVEATVNYATEKAKVTFREDVSVADLIATVEATGYTAKEPAPVRTESGPAEGEREEAADELRPLRQRLLTAAVLAIPVIAMSMVPALQFEYWQWLSLTLTAPVVTYAAWPFHRAAWTNARHGAATMDTLISVGTSAAFLWSLWALFFGTAGTPGMTHPFELTIGRSDGAGNIYLEAAAGVTAFILAGRYFEARSKRKAGAALRALLELGAKDVTVLRADGRELTVPTDELKVGDRFLVRPGEKIATDGTVVEGSSAVDASMLTGESVPVEVAPGDAVTGATLNAGGRLVVEASRVGADTQLARMAKLVEDAQNGKAAAQRLADKISAVFVPVVIGLALATLGFWLGNGSGLTAAFTAAVSVLIIACPCALGLATPTALMVGTGRGAQLGILIKGPEVLETTRKVDTIVLDKTGTVTTGRMTLLAVHTTDTTDEAEVLRLAGALEHSSEHPIARAVADGAAAKVGPLPTPEDFANIAGLGVQGVVDGHAVLVGRENLLGDWAMELTPALKRAKEEAEAAGRTAIAVAWDGEARAVLEVADAIKETSPEAIRRLRALGLTPILLTGDNRAVAEAVAAEVGIDTVYAEVMPQDKVDVVKSLQAEGRSVAMVGDGVNDAAALAQADLGLAMGTGTDAAIEAGDLTLVRGDLRAAADAIRLSRKTLGTIKSNLFWAFAYNVAALPLAAAGLLNPMIAGAAMAFSSVFVVGNSLRLRGFQATV
>CP032698.1|AYG81399.1|3956923_3957838_-|hypothetical-protein
MKFVMGTGLKITAFAAALAATFGTAYGVGKGVDPIVAQPAGHAAHGEPTAKAGHGGHEEQDGAAELPGGLQIAEGGYALDLRTPRLEAGRAAEIRFAVTGHDGRPVTAFKSEHGKELHLVVASDDLAVYRHLHPVRAADGTWSVPAELPEAGGYRVFADFTPGDTKDAKNLVLGADLAVSGAYAPKELPAPTATAPVEDGYTVSLAGDLTPGRTAELKLSVTKEGRPVTDLEPYLGAYGHLVALRAGDLAYLHVHPNEGGPGPVVSFGATVPSAGTYRLFLDFQHGGKVRTAGFTVAAGGHLAA
>CP032698.1|AYG81398.1|3956168_3956858_-|Copper-homeostasis-protein-CutC
MSNRALLEVIALDAQDAVAAQAGGADRLELVTDMAADGLTPSRETFAAIRAAVDIPLRVMLRAHDGFAAGDVDALLRDAEALRAEGADEFVLGFLDETGGPDMAALRALAPVLDGCRWTFHRAVDRAASRDALRKELSGLAGLDTYLTAGSPLGVDDGLPVLLAEAARHGEPGYEPRILVGGGLQLTHLPVLRDAGIDAVHIGGASRPGGWSEPVSPAAVAEWRAALDA
>CP032698.1|AYG81397.1|3955627_3956107_+|hypothetical-protein
MHLDMEPRAEQLPATVCAFRKRFASTRRAAGLARRLAQGQLAAWGIAPESEASRTAALLVAELAANAVLHAYVSGRGFEVGVALREDGVLRIEVTDTRADKALPVVASAPAADCESGRGLLLVQAFADHWGTVEGPTPLKTVWAQLALPEGEFIRVLRP
>CP032698.1|AYG81396.1|3954587_3955469_-|hypothetical-protein
MPWDHEDHDDHEDQAGLDDHEGRDGEPEASDSLRTFGAVVQALREHAGLSRAQLGALVGYSKHTVASVELGRRMPDPAFIERAERALGNTGALTAAARHLSRQPGLASWFRRWARLERTAISLYTYESRLIPGLLQTEAYALALFRAQLPPLADAQIDANMVARLKRQRLLTERPNTAYSFIVDEHVFARRTGGPDVTRELIDYVLERTAARNVELQILPAGLGVHAGLAGPIRLAETPAHRWFGYCEGQESGIFVSDPKLISTLHMRYAKLRSQALTPEQSVGRLELLRGAP
>CP032698.1|AYG81395.1|3954219_3954591_-|hypothetical-protein
MSTTELGWFKSSYSSGSGDDCVEVALDWRKSTYSSGSGDSCVEVAECWSKSSYSSAEGDSCVEVSACWSKSSYSSGDGDSCVEVAATPAVIHVRDSKDKAGPQLTLSPGAWGEFVAYAGVGPL
>CP032698.1|AYG81394.1|3952158_3954225_+|DNA-helicase-IV
MPAHAPTPNPLDHERTHLAHSRAALRAMREDVQALDIKDVTANWVNAAVLQRQIDDRIKALADLSHTPLFFGRLDYLHAPGADLAEGAGGERFYIGRRHVHDADGDPMVIDWRAPVSQPFYRASKKDPLDVSLRRRFGYTGGELTAYEDEHLMDATETARTSKLLQAEIERPRVGPMRDIVATIQPEQDEIVRSGLSGSVCVQGGPGTGKTAVGLHRVAYLLYAHRDRLARTGTLVIGPNKSFLHYIEQVLPALGELEVKQATVDDLVASTGVEVRGTDPAEAAVIKGDARMAEVLRRAVWSHVTTPSEPLVVVRGSRRWRVPAYELATIVEELRDRDIRYGAAREALPQRIAHTVLVRMEQAGEAPDDRVQDAVARNTAVKAAVKAIWPPVDPAKLVLRLLNEPAFLATHAEGILTDDEQKAILAPKPARSVKAAKWSAADAVLIDETNDLVARTPSLGHVVLDEAQDLSPMQYRAVGRRCTTGSATVLGDLAQGTTPWATASWAEALRHLGKGDAVVEELTAGFRVPREVIAYASKLLPSISPGLAPVESVRETPGSLDVRAASTPAELDAAVVAACEESLAHEGSIGLIAADARIPVLAKALEAAGLAHLDPGEETTATSRLTLVPASLAKGLEYDYVVLDEPTAVVDGEPDERTGLRRLYVALTRAVSGLTIVHASPLPPQLAL
>CP032698.1|AYG81393.1|3950852_3951752_+|putative-ECF-RNA-polymerase-sigma-factor-SigI
MVDDEYLAQRFEEHRGHLRAVAYRMLGSLSEAEDAVQEGWLRASRADSGAVDNLGGWLTTIVARICLNMLRARGTRREAALDVGEYEYVHVPDPVLGPVDGADPEQEVLLADSVGLALMVVLETLAPAERLAFVLHDMFAVPFEDIAPIVDKTPAATRQLASRARRRVQGRVPSPSPDRARQREVVEAFISAARGGDFEALLALLDPDVVLRADAGALPTTKLVRGARAVAEQANSFRKLAAFNRLVLVNGAPGILAVVGGRVVSVLAFTLGEDARITELNILADPTRLHPLNPLGLTP
>CP032698.1|AYG81392.1|3950363_3950570_-|hypothetical-protein
MSTTTCTPAPSARPGTPRGATASGAAPHRTHKIGNAVRAAKVLAGAAFSVVVMGEFAEEAGVRRRHQG
>CP032698.1|AYG81402.1|3961800_3962499_+|hypothetical-protein
MRASTEWLGARPATLGRMPHPNDLLLRWHQAILATRSPANSPVDPTPYGENLLARWAEPQRHYHDTTHLTAVLDHIDVLERYADQPDLVRLAAWFHDAVYLPDRSENEERSARLAERALPEAGLSREDTAEVARLVRLTVTHAPEEGDANGAVLCDADLAILAAAPDAYAAYAAAVREEYAFVPDEAFRSGRGEVLAQLLALPALFRTPHGVRAWEGPARENLEAELTLLTA
>CP032698.1|AYG81403.1|3962545_3963061_+|hypothetical-protein
MLPVTVQADRIALHELTRASAAALQDGGSGGWRWAPGGPHEGSRFAAAKMLAGIETGRHRTGWGAYVIVRAEDGRAIGGIGFHGPPEDGRVEIGYDLAESARGQGYATESLAVLTAWALAQPDVETVYATTDEDNTASQRVLERAGFRRVGDTPRTIGGRRRQHVFEHTGA
>CP032698.1|AYG81404.1|3963631_3964927_+|Inner-membrane-transport-protein-YdhP
MALGMPAEPIPTPVPAPTPTPPPPPAQGARMPLAVYILGLSVFALGTSEFMLTGLLPAIADDMNVSIPQAGLLISAFAIGMVVGAPLLAVATLRLPRRTTLIALITVFGLGQVAGALAPNYALLFASRIVSALACAGFWAVGAAVAIAMVPVNARARAMAVMIGGLSIANVLGVPLGALLGDGLGWRSAFWAVGAASAIALVGILTRIPRIPLPAEKPRLRQELRIYRDPQVLFSVAVTALAAGGVFCAFSYLKPLLTDVAHVDAGWVPAVLGLFGVGALIGTTIGGRVADAHLFGVLLSGITASTVFLVALALFASTPAVAVALSFLIGLSAFYTAPALNARMFNVGGAAPTLAGATTTSSFNLGNTAGPWLGGLVISANLGFAATAWAGAAMTVLALVLVAASLRLHRSQFRVVARSAERAPAAACVEA
>CP032698.1|AYG81405.1|3965173_3965377_-|Cold-shock-protein-ScoF
MATGTVKWFNAEKGFGFIAQDGGGPDVFVHYSAINSTGFRELQENQAVVFDVTQGPKGPQAENVSPA
>CP032698.1|AYG81406.1|3965734_3966001_-|hypothetical-protein
MTLYIDPPTWPGHGRMWSHLVSDVSYEELHTFAASIGCPSRAFDGDHYDVPSHRYADAVRAGAVEIGSKELVRRLTGAGLRRPKGRPA
>CP032698.1|AYG81407.1|3965997_3966384_-|hypothetical-protein
MEGMDDVQPLEQALHAARALVLADLAARDVAHADVVSMVEDAVTHRRWWVEQWPEGTEYVAGLVAQDVQDALLERYGRWPLCPVCDGGDPHALDVEPELGPDPHWVCGKAGVVVSRVGGLGGLGGPVG
>CP032698.1|AYG81408.1|3966540_3967446_+|HTH-type-transcriptional-regulator-MurR
MKESFSGGAPPAPAALAAKVRTLAPSMTRSMQRVAEAVAGDPAGCAALTVTGLAELTGTSEATVVRTARLLGYPGYRDLRLALAGLAAQQQSGRAPAVTADIAVDDPIADVVAKLAYDEQQTLADTAAALDTVQLGAAVGALAGARRIDIYGVGASSLVGQDLAQKLLRIGLIAHAHTDPHLAVTNAVQLRSGDAAVAITHSGSTGDVIEPLRVAFDRGATTIAITGRPDGPISQYADHVLTTSTARESELRPAAMSSRTSQLLVVDCLFIGIAQRTYETAAPALSASYEALAHRHNPRTR
>CP032698.1|AYG81409.1|3967511_3968441_+|N-acetylmuramic-acid-6-phosphate-etherase
MTTQDYAELRAQLATLTTEAFRPELAEIDQLPTAEIARIMNGEDATVPAAVAERLPDIAAAIDATAARMASGGRLVYAGAGTAGRLGVLDASECPPTFNTDPSEVVGLIAGGPSAMVRAVEGAEDSRQLAAEDLTALGLTSLDTVVGVSASGRTPYAVGAVEHARRLGALTIGLSCNADSALAAAAEHGIEVVVGPELLTGSTRLKSGTAQKLVLNMISTITMIRLGKTYGNLMVDVRASNEKLRARSRRIVALATGAGDAEIEAALAATDGEVKNAILVILGGVEGATAARLLSDSQGHLRAALHAAL
>CP032698.1|AYG81410.1|3968654_3969083_+|hypothetical-protein
MSTAAYPESWQRLLDQAGPPPAPSLHLASAAPGGGDLHHTPKPWNDAAGAAHSLRTDTDTARSGLITAHAGLDTSGAGLLSVTALKTVLTSWEQRLGAVRDECADLEPKLREVARTMGGTDHAVRSSIAGYADPVPADEKGR
>CP032698.1|AYG81411.1|3969087_3970950_+|hypothetical-protein
MLTWQHLRDLRPAGLQSAADGWGDVSRHADAARDRLSNEMLGAIEKSQTGNAADSAAGRLRGLDRNYDYIHIECGLIRTALDSLAYELAGPQRKLLDALDEAAALKFTVGTDGSVSYPPGGENLISKQPLPGGSATGGSPLLSRPPALTQTPPGFTDTNPNHAKAQAIADQILAALQEARRVDERFSTTLAKLKAEPGLGVATATWQDMAADAAAVRAVADQYLKNDIPTAKSPAERKAWWTYLTEKEREEYLAAYPDIIGNLEGIPSAVRDTANRDNLQVLIGKLAGAGDEASKTKLAGLLSIDKQLNAVPEPGVPPMYLLGIGDHDNGRAIVSFGDPDAARNVSAYVPGLSTKLSEHFATNDIERARATAKSAAFLDHSSASIVWLGYDAPQLPAEQVVDDLAVMGTHDAEVGATAYNHFMDGIRTTNQNADPHITAIGHSYGSLTVGLAAQQAGGIPGADDIILVGSPGTEAKTADDLGVGRDHVYVGAAENDPVTMLPNKKEATGVLGGAAVGALGGFVVPMPGGTILGAAEGALEGYIIGDAASDPSQIYFGTDPANHAFGAHRFQVGDGPRPFIDGQGPVPAHSNYFDDDPVSAANIAAIVAGQPQLVTSQEPR

Crispr_ID: CP032698_33

• CRISPR_ID: CP032698_33
• CRISPR_location: 3989053-3989152
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_33

Consensus_repeat	Method
CCCCTGGGGCTCCGCCCCAGACCCC	CRISPRCasFinder

spacers of CP032698_33

>33.1|3989078|50|CP032698|CRISPRCasFinder
GGACGCCTTTGCCCACCCGCCCGCCCGTGACGGGGGTTGGACAGCCCCGG

CRISPR arrays and Neighbor proteins around CP032698_33

CRISPR arrays

The CRISPR arrays of CP032698_33

>merge|CP032698|33|3989053-3989152|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCGGACGCCTTTGCCCACCCGCCCGCCCGTGACGGGGGTTGGACAGCCCCGGCCCCTGGGGCTGCGCCCCAGACCCC

>CP032698|33|26|3989053-3989152|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCC	GGACGCCTTTGCCCACCCGCCCGCCCGTGACGGGGGTTGGACAGCCCCGG
CCCCTGGGGCTGCGCCCCAGACCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81435.1|3995418_3996564_+|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl|CDD|238434
CP032698.1|AYG81433.1|3992889_3994155_-|Multiple-sugar-binding-protein	unknown	unknown	gnl|CDD|270452
CP032698.1|AYG81430.1|3989228_3990842_-|Tripeptidyl-aminopeptidase	unknown	unknown	gnl|CDD|312032
CP032698.1|AYG81422.1|3979760_3980264_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81420.1|3977030_3978140_-|Intracellular-serine-protease	unknown	unknown	gnl|CDD|274856
CP032698.1|AYG81431.1|3991280_3992120_-|Trehalose-phosphate-phosphatase	unknown	unknown	gnl|CDD|319767
CP032698.1|AYG81438.1|3998704_4000378_-|putative-signaling-protein	unknown	unknown	gnl|CDD|143635
CP032698.1|AYG81425.1|3983859_3984063_-|Cold-shock-protein-CspA	unknown	unknown	gnl|CDD|224197
CP032698.1|AYG81427.1|3984861_3986229_-|Threonine-synthase	unknown	unknown	gnl|CDD|236065
CP032698.1|AYG81429.1|3987575_3989051_+|Trehalose-6-phosphate-synthase	unknown	unknown	gnl|CDD|340820
CP032698.1|AYG81424.1|3981418_3983041_-|60-kDa-chaperonin-2	unknown	unknown	gnl|CDD|234573
CP032698.1|AYG81423.1|3980400_3981174_-|hypothetical-protein	unknown	unknown	gnl|CDD|226123
CP032698.1|AYG81426.1|3984464_3984740_-|Sulfur-carrier-protein-CysO	unknown	unknown	gnl|CDD|340594
CP032698.1|AYG81428.1|3986494_3987442_+|Glucosyl-3-phosphoglycerate-synthase	unknown	unknown	gnl|CDD|237556
CP032698.1|AYG81432.1|3992186_3992420_-|hypothetical-protein	unknown	unknown	gnl|CDD|378688
CP032698.1|AYG81437.1|3997589_3998594_-|Exo-beta-D-glucosaminidase	unknown	unknown	gnl|CDD|271149
CP032698.1|AYG81434.1|3994390_3995419_+|Glucokinase	unknown	unknown	gnl|CDD|366120
CP032698.1|AYG81436.1|3996641_3997562_+|Tagatose-6-phosphate-kinase	unknown	unknown	gnl|CDD|274464
CP032698.1|AYG81421.1|3978273_3979761_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81439.1|4000708_4001275_+|NADH-dependent-flavin-reductase	unknown	unknown	gnl|CDD|214900

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81435.1|3995418_3996564_+|N-acetylglucosamine-6-phosphate-deacetylase	gnl|CDD|238434	cd00854, NagA, N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.	7.88715e-156
CP032698.1|AYG81433.1|3992889_3994155_-|Multiple-sugar-binding-protein	gnl|CDD|270452	cd14749, PBP2_XBP1_like, The periplasmic-binding component of ABC transport systems specific for xylo-oligosaccharides; possesses type 2 periplasmic binding fold. This group represents the periplasmic component of an ABC transport system XBP1 that shows preference for xylo-oligosaccharides in the order of xylotriose > xylobiose > xylotetraose. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 proteins are comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.65726e-54
CP032698.1|AYG81430.1|3989228_3990842_-|Tripeptidyl-aminopeptidase	gnl|CDD|312032	pfam08386, Abhydrolase_4, TAP-like protein. This is a family of putative bacterial peptidases and hydrolases that bear similarity to a tripeptidyl aminopeptidase isolated from Streptomyces lividans. A member of this family is thought to be involved in the C-terminal processing of propionicin F, a bacteriocidin characterized from Propionibacterium freudenreichii.	2.31502e-15
CP032698.1|AYG81437.1|3997589_3998594_-|Exo-beta-D-glucosaminidase	gnl|CDD|271149	cd04083, CBM35_Lmo2446-like, Carbohydrate Binding Module 35 (CBM35) domains similar to Lmo2446. This family includes carbohydrate binding module 35 (CBM35) domains that are appended to several carbohydrate binding enzymes. Some CBM35 domains belonging to this family are appended to glycoside hydrolase (GH) family domains, including glycoside hydrolase family 31 (GH31), for example the CBM35 domain of Lmo2446, an uncharacterized protein from Listeria monocytogenes EGD-e. These CBM35s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. GH31 has a wide range of hydrolytic activities such as alpha-glucosidase, alpha-xylosidase, 6-alpha-glucosyltransferase, or alpha-1,4-glucan lyase, cleaving a terminal carbohydrate moiety from a substrate that may be a starch or a glycoprotein. Most characterized GH31 enzymes are alpha-glucosidases.	6.74125e-17
CP032698.1|AYG81420.1|3977030_3978140_-|Intracellular-serine-protease	gnl|CDD|274856	TIGR03921, T7SS_mycosin, type VII secretion-associated serine protease mycosin. Members of this family are subtilisin-related serine proteases, found strictly in the Actinobacteria and associated with type VII secretion operons. The designation mycosin is used for members from Mycobacterium. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair].	1.21338e-93
CP032698.1|AYG81431.1|3991280_3992120_-|Trehalose-phosphate-phosphatase	gnl|CDD|319767	cd01627, HAD_TPP, trehalose-phosphate phosphatase similar to Escherichia coli trehalose-6-phosphate phosphatase OtsB and Saccharomyces cerevisiae trehalose-phosphatase TPS2. Trehalose biosynthesis in bacteria is known through three pathways - OtsAB, TreYZ and TreS. The OtsAB pathway, also known as the trehalose 6-phosphate synthase (TSP)/ Trehalose-6-phosphate phosphatase (TPP) pathway, is the most common route known to be involved in the stress response of Escherichia coli. It involves converting glucose-6-phosphate and UDP-glucose to form trehalose-6-phosphate (T6P), catalyzed by TPS, the product of the otsA gene, this step is followed by the dephosphorylation of T6P to yield trehalose and inorganic phosphate, catalyzed by a specific TPP, the product of otsB gene. This OtsAB (or TSP/TPP) pathway, is also the most common route known to be involved in the stress response of yeast In Saccharomyces cerevisiae, the corresponding enzymes, TPS1p and TPS2p, form a multimeric synthase complex together with additional regulatory subunits encoded by Tsl1 and Tps3. Trehalose is a common disaccharide accumulated by organisms as a reservation of carbohydrate and in response to unfavorable growth conditions. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.46008e-28
CP032698.1|AYG81439.1|4000708_4001275_+|NADH-dependent-flavin-reductase	gnl|CDD|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	5.97839e-47
CP032698.1|AYG81425.1|3983859_3984063_-|Cold-shock-protein-CspA	gnl|CDD|224197	COG1278, CspC, Cold shock proteins [Transcription].	6.48086e-35
CP032698.1|AYG81427.1|3984861_3986229_-|Threonine-synthase	gnl|CDD|236065	PRK07591, PRK07591, threonine synthase; Validated.	0
CP032698.1|AYG81429.1|3987575_3989051_+|Trehalose-6-phosphate-synthase	gnl|CDD|340820	cd03788, GT20_TPS, trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.	5.15455e-136
CP032698.1|AYG81424.1|3981418_3983041_-|60-kDa-chaperonin-2	gnl|CDD|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
CP032698.1|AYG81423.1|3980400_3981174_-|hypothetical-protein	gnl|CDD|226123	COG3595, COG3595, Uncharacterized conserved protein [Function unknown].	1.16091e-05
CP032698.1|AYG81426.1|3984464_3984740_-|Sulfur-carrier-protein-CysO	gnl|CDD|340594	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins. CysO, also termed 9.5 kDa culture filtrate antigen cfp10A, together with CysM (Cysteine synthase M), forms a protein complex CysM-CysO that represents a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. The replacement of the acetyl group of O-acetylserine by CysO thiocarboxylate to generate a protein-bound cysteine is catalyzed by CysM in a pyridoxal 5?-phosphate (PLP)-dependent manner. The family also includes QbsE that functions as the sulfide donor for the biosynthesis of thioquinolobactin in Pseudomonas fluorescens. A JAMM motif protein QbsD catalyzes removal of the carboxy-terminal dipeptide from QbsE. Both CysO and QbsE are similar to prokaryotic sulfur carrier proteins such as ThiS and MoaD, containing the beta-grasp ubiquitin-like fold.	1.0052e-41
CP032698.1|AYG81428.1|3986494_3987442_+|Glucosyl-3-phosphoglycerate-synthase	gnl|CDD|237556	PRK13915, PRK13915, putative glucosyl-3-phosphoglycerate synthase; Provisional.	3.55195e-166
CP032698.1|AYG81432.1|3992186_3992420_-|hypothetical-protein	gnl|CDD|378688	pfam11662, DUF3263, Protein of unknown function (DUF3263). This family of proteins with unknown function appears to be restricted to Actinobacteria.	8.26643e-25
CP032698.1|AYG81434.1|3994390_3995419_+|Glucokinase	gnl|CDD|366120	pfam00480, ROK, ROK family.	1.45156e-55
CP032698.1|AYG81436.1|3996641_3997562_+|Tagatose-6-phosphate-kinase	gnl|CDD|274464	TIGR03168, 1-PFK, hexose kinase, 1-phosphofructokinase family. This family consists largely of 1-phosphofructokinases, but also includes tagatose-6-kinases and 6-phosphofructokinases.	2.53007e-109
CP032698.1|AYG81438.1|3998704_4000378_-|putative-signaling-protein	gnl|CDD|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	8.7497e-42

Protein sequences

>CP032698.1|AYG81429.1|3987575_3989051_+|Trehalose-6-phosphate-synthase
MVTTHAAPRAQVLLASNRGPVSYALKDDGSLEPKRGGGGLVSGLSAIGSDVESVWVCAALGEGDREAVRRGVGEHGVRMLDIDAEVFSDAYNGIANSVLWFVQHMLYQTPLEPVFDAEFRRQWASYEAYNRAFAQALAAEAGDGARVLVQDYHLALVPGMLRELRPDLRIGHFSHTPWAPVDYFRMLPDDIARQLLRGMLGADRLGFLTRRWASAFMASVAGVLPAGEGELFGAAEGESGRCFFRHAPAGSLPARDTDIAVHSLGADGDFLRRRSHEPDVEERMAALREQIGAGRKTIVRVDRTELSKNIVRGLLAYRHLLEEHPEWRERVVHVAFAYPSRQDLAVYREYTEEVARVAADINSSYGTESWTPVVLHVQDDFARSLAAYRLADVALVNPVRDGMNLVAKEVPVVSDAGCVLVLSREAGAYEELGEDALVVNPYDVTGTASALYAALSMGEGERGERTKRLAAAGTALPPRAWFLGQLEALAP
>CP032698.1|AYG81428.1|3986494_3987442_+|Glucosyl-3-phosphoglycerate-synthase
MLEEVERWLSRRSWSAAERPLDRMLAAKHRTGTTVSVVLPALDEEATVGAIVATIRRELMTDAVPLVDELVVVDSGSRDRTAEVAAAAGARVVHRDAILPRVPALPGKGEVLWRSLLVTSGDVVCFVDADLRDFDAGFVSGIVGPLLTDPDVAFVKAMYDRPFGTTVGQGGRVTELVARPLLNLHWPRLAGVVQPLGGEYAARRSLLERLPFPVGYGVELALLVDALHTVGLDALAQVDVGVRKHRHQDGQALGRMAAAIYRTAQLRLSRGHLVRPELTQFVRGEHGFVPRTYAVDTEERPPMRDIEEYAVHRAA
>CP032698.1|AYG81427.1|3984861_3986229_-|Threonine-synthase
MAKFALRKMRRKGLPSMSAQTVESRTSTENPSDSAGTSVDLGPASGLSCRECGQRFELGPIFACELCFGPLEVAYDLPLGDPEALRKQIEAGPENIWRYAPLLPVPADVADKPNLNPGFTKLVKAENLARELGVESGKLFVKDDSGNPTHSFKDRVVAQALEAARAFGFTTLSCSSTGNLAGAVGAAAARAGFRSCVFIPHDLEQGKVVMAAVYGGELVGIEGNYDDVNRFCSELIGDPLGEGWGFVNVNLRPYYGEGSKTLAYEICEQLGWRLPDQLVIPIASGSQLTKIDKGLQELIKLGLVEDKPYKIFGAQAEGCSPVSTAFKAGHDVVRPQKPDTIAKSLAIGNPADGPYVLDIARRTGGAVEDVNDEQIVDAIKLLARTEGIFAETAGGVTVGVTKKLIEAGLLDPTLTTVVLNTGDGLKTLDAVAATSQATATIRPSLDAFRDAGLAH
>CP032698.1|AYG81426.1|3984464_3984740_-|Sulfur-carrier-protein-CysO
MSVNVRIPTILRTYTGGKAEVAAEGATLAEVIADLEKNHTGIAARVLDDQGKLRRFVNVYVNDDDVRFEQGLETATPDGAGVSIIPAVAGG
>CP032698.1|AYG81425.1|3983859_3984063_-|Cold-shock-protein-CspA
MAQGTVKWFNAEKGYGFIAVDGGADVFVHYSAIQMDGYRTLEEGQRVEFEISQGQKGPQADMVKLAV
>CP032698.1|AYG81424.1|3981418_3983041_-|60-kDa-chaperonin-2
MAKIIAFDEEARRGLERGMNQLADAVKVTLGPKGRNVVLEKKWGAPTITNDGVSIAKEIELEDPYEKIGAELVKEVAKKTDDVAGDGTTTATVLAQALVREGLRNVAAGANPMALKRGIEKAVEAVSAALLEQAKDVETKEQIASTASISAADTQIGELIAEAMDKVGKEGVITVEESQTFGLELELTEGMRFDKGYISAYFATDMERMEASLDDPYILIVNSKISSVKDLLPLLEKVMQSGKPLLIIAEDVEGEALSTLVVNKIRGTFKSVAVKAPGFGDRRKAMLGDIAILTGGTVISEEVGLKLENAGLDLLGRARKVVITKDETTIVDGSGDSDQVQGRVNQIRAEIENSDSDYDREKLQERLAKLAGGVAVIKAGAATEVELKERKHRIEDAVRNAKAAVEEGIVAGGGVALLQASAVFDKLELEGDEATGAKAVKLALEAPLKQIAVNGGLEGGVIVEKVRNLPVGHGLNAATGEYVDMIAEGIIDPAKVTRSALQNAASIAALFLTTEAVIADKPEKAAAAAPGGMPGGDMDF
>CP032698.1|AYG81423.1|3980400_3981174_-|hypothetical-protein
MTTTRLRTRSVAAVPRTALTALTALTVLAVGALGGCGPMDDTTFKDDTTVKSTITAVRIDGTSDGFRVRGKQGLTTSSVHREVTYRGKKKPTGSTYRVENGVLVLGGCAGRCSVDYVVDVPAGIPVTGSTKAGGLSLSAVGQVQVSTGDGAVKVRGATGPVDIRTSNGSIDANGLKGTATTARTSNGAITLTPATVQDVTAQTSNGSITVTAPRAPYRVSAQSTHGHKALGITDAPSAPHHLTLTTTNGAITLNPAK
>CP032698.1|AYG81422.1|3979760_3980264_-|hypothetical-protein
MATSEDKAAPQSPPWTFGMLGLGAAAAGDVVTELSSFTNFQQRVDELIRTLKGSPAGPGEVGQERLPREHFGGGAGAFTEASGLYTSYETVITELERLSALLSDSMEGMGIAVLASHKGYENIDADVRKRMIAISAEAKKHYGGDYTPEQTHPGPKSPSGGDAGGTI
>CP032698.1|AYG81421.1|3978273_3979761_-|hypothetical-protein
MGASTPFEGMSHEAMLAWLDQANSGTVQGAADRLAAAAKEIRKIAEDLKVRPQWVEWKGAGADAFRTWSADLANATLRLGDFSEGSSKWLGHASNAIASAQASIPRDQPAAQANLTAAKAAHNDPDAAQIARKSASELAALEADKEKVRQEAVAQMRKLGQAYEQSATQMNVLERPKFPPPPTAIAPEYDRSRDRNGMDVGSGRAGQDTASPAHVTPARAAREQMPDSDASRQARQPGLGVPEPQALIDAQRPVRTDIDSVTSFPGAVQTPGPGGNATGPATSGEKPAVSLYPPAFRGGLSASPVPVDPEPPTAGQRSPWMSGESPSGRTSVRMPANSPGITGGRPMPAPQSRSGGQIPKGTVVGAGDTQTHGATRPITGAGPVGQVAGRPGAMPKQGPMPLRSGVSGGSAQQAGRAAGPRSVSAGANGERGGISGGRPIAGNAVGGAAGVGRPPRDSQKGRSQREAGGSARGNLVEDDETWLRDDPRVVPPVID
>CP032698.1|AYG81420.1|3977030_3978140_-|Intracellular-serine-protease
MREKQWFLDAMKADDMWHTSRGTGITVAVIDSGVDSSNPDLAGRILPGRDFAQGQPGDEHTDLEGHGTGMAGLIAGTGARDGGFGAFGLAPGAKILPVRMPKSGDVNQAEGDKRFNVTASQAIRYAADHDARVINISLASAEGSPQLSAAVKYALDKGSLVFAAVGNSGDSGNEVEYPAATPGVVGVGAVGKDLHRTAWSQYGPQVDMAAPGAEMVHACGGKTGLCKTDGTSDASALASASAALIWSKHPTWTNNQVLRVMLNTIGAPTDGSKRNDSIGYGIVRPRVALENPGDPGPADVYPLPDLTPSPTPSAPSPAAAPARADAPQASKPEDGSTSAPYWVVGATGILVVGLGLWALRKRRQGVGAL
>CP032698.1|AYG81430.1|3989228_3990842_-|Tripeptidyl-aminopeptidase
MRPVLHVTALALVTSLVTSLATIPATAAPTAPTAPTMPTSTSTITTSTTPTTSTTSTLDRYYNQRLRWGSCARDADDATGRELDGTGLQCATATVPLNYSDPRGRTITIAMSRLKATDTRHRIGSLLINTGGPGGPGVGAPPAIRKAMKDVGARYDIIGFDPRFVGRSTPLDCGWPVGMPWLSAGATRASFDRQVTLHKSLADKCRAADASVLPYVTTRNTARDMDVMRRALGERRISYLGYSYGTYLGTVYTQMFPGRTDRVVLDGAFAPDDYRARLLKGTERENEEALADWAGWAAERHGVYGLGRSRAEVLATVEHVRAVSARAPLTIGTGADAFRIDDTQVPLLLYTGTADDTAAARASFADQLSLLAAAADGRPPRPLSPEFEAGLRYALRGEGGGATGMQTAIICGDVSDSHDPESYWRDVRRSRATHPLFGPLANNITPCAFWDRPREAPTRVSHDAKALIVAATGDPRTTYRSSLELHRLLPSSGLLTVEGANRHGLYGRYGSACVDDRVNTYLSTGTPPPDTPTCPTP
>CP032698.1|AYG81431.1|3991280_3992120_-|Trehalose-phosphate-phosphatase
MGSQPEPLPTPVTQYGRDGLAAILARPERAVIAVDFDGTLAEIVADPEQARAHPDAVPALAALAPHVASVAVVTGRPAGVAVRYGGFAGVPGLEHLVVLGHYGAERWDAVTGTVHTPDPHPGVAAARAELPGFLEAHGAWRGTWVEEKGQAVAVHTRRAQDPQAAFEALRAPLTDLAAQHGLVIEPGRMVLELRPPGMDKGVALTAYLREVGAESVLYAGDDLGDLPAFGAVEKLRSDGMPGLLVAADTVIDELAEKGDLLLDGPASVATFLKALATHM
>CP032698.1|AYG81432.1|3992186_3992420_-|hypothetical-protein
MADDDLDARARAVLHLETRPWPTPGAKERAIREELGVSPTRYYQLLNALLDDTRALAHDPVTVNRLRRLREEQRARR
>CP032698.1|AYG81433.1|3992889_3994155_-|Multiple-sugar-binding-protein
MRRRFLGLTAAVAAFGMTAVLSGCGGESGSGDVTLKLVAADYDIAGGSSTKTYWHNVVEDFEKKNPNIKVDVQIFSWDVVDAKVAEMVKAGNAPDIAQIGAYSDYASSGKLYSVDQLLSIPVEANFLSPLADAGNVKRVQYGMPFVASTRLLFYNQTLFEQAHIKPPTTWAEIASDAKALKAKGVKTPFALPLGSEEAQAETMMWMLSDNGGYTNTVDGYDIDSPENIQAFDWLKANLVEPELTGPVAPGKLNRQDAFDAFAKGEVGMLNGHPSLMEAAKKKGIKFGMVPLPGQNGQAKAAMGVADWIMGFKQGGHRAQIGKFLDFTFSDANVLKFADQYDLLPSTVSASSAMAADPKHKELKPFLAALPTSELPPVGKTSWPKVSETVKKKIGSAVAPGGSPKSVLQDIAKVAMDAENAE
>CP032698.1|AYG81434.1|3994390_3995419_+|Glucokinase
MRHVIALDVGGTGMKAALVGAETALSAGNPPGPPQLLHEARRPTGRERGPDAVVESILAFAADLRAYGEEHFGESAVAAGVAVPGIVDAENGIATYAANLGWRDVPMRRLLSERLHGVPVALGHDVRTGGLAEGRIGAGNGTDRFLFVPLGTGIAGAIGIDGRVEPGAHGFAGEIGHIVVRPGGIACPCGQRGCLERLASASAVTLAWAEASGDPDADAADCAKAVESGDPRALAVWRNAIEALADGLVTALTLLDPRVLIIGGGLAEAGETLFVPLRAAVEERVTFQKLPEIIPAALGDTAGCLGAGLLAWDLVAATAGTGSRPDPHPHPGSDPDSSEVTV
>CP032698.1|AYG81435.1|3995418_3996564_+|N-acetylglucosamine-6-phosphate-deacetylase
MAASKVLSGARVVLPTGVVENGRVIVDGTSIAGSAPADAVALDLSGHWVVPGFVDMHNHGGGGASFSNGTVEDVLKGVHTHRLHGTTTLVASTVTGEMDVLAQRAGLLSELVEQGDLAGIHFEGPFISPCRKGAHSEGLLRHPDPAEVRKLLDAARGTAKMVTLATELPGGLDSVRLLAEHGVIAAIGHTDASYEQTVEAIDAGATVATHLFNAMPALGHREPGPIAALLEDERITVELINDGTHLHPAALELAFHHKGADRVAFITDAMDAAGFGDGLYHLGPLEVEVKEGVARLVEGGSIAGSTLTLDRAFKRSVTVDGLSVEDTVRALSANPARLLGLDDTVGSLEPGKDADLVVLDADFAVKGVLRKGSWVVEPELG
>CP032698.1|AYG81436.1|3996641_3997562_+|Tagatose-6-phosphate-kinase
MILTVTLNTALDITYRVPALVPHASHRVEEVTERPGGKGLNVARVLAALGHETVVTGFVGGPSGEVLRALLAGLAPVDELVPIRGATRRTIAVADAATGDTTQLNEPGPVVSSTEWDAFLTAYGRLLDGAEAVALCGSLPPGLPVGAYAQLVRQARTAKVPVLLDTSGEALRRGIAARPDLVKPNADELAQLTGSREPLRAARDARRRGAHTVVASLGAEGLLAASPDGLWQAAPPAAVRGNPTGAGDSAVAGLLSGLVEGLDWPGRLTRAVALSAATVLAPAAGEFDREAYAKMLGSVRVSEHAH
>CP032698.1|AYG81437.1|3997589_3998594_-|Exo-beta-D-glucosaminidase
MTTPGNNGANTPEDDDPFGYLYADGQATGNPARSGGGYGYPGPAAGQQQPGVPRTSYNQVRTVGERQYGQIPQQQYQGPPQQYQGPPQQHQGPPQQQYGQPTAQYAAPETYPGATPPRQGPPPQQTGSGGRGPNTKGLLIGAVAVVAAVVIGIAVALASNSDNKDKKDDAAKPNTSASSQPPSPSTDPTSSPSAPADLPKGDAATLTLGGPAQVGTNVPGAKGTGGAFVTNFNNVGSSVTWKVKVPKAGSYKLNLRFGVPGADANATITLNGKAESRPMNMKNFAHSPAGDWAKGWQTTFANVTLDKGDNEIKLSCEQGNQCNANLDQLWLTTA
>CP032698.1|AYG81438.1|3998704_4000378_-|putative-signaling-protein
METESEPYVRLATLRQLHQVVGELNTARSLADTLQTVADGVIAGLGYELACVNLVRPDGDLVVAAFAGNAAAEALITGRVGSRTSWERRLSMGEDWDGLRFIPHTEGWVLLEDDVPQWYTEGPDPRFADEWHPQDRLYAPMYSAGGTQELLGVISVDKPRNGRKPGAWGREALQMYASQSAIAISNARLRANMQRALVRLEREQQALRASEESFRQAFEYAPSGMAIAEMGGDQHGRLLRTNDALCRLLGRPASVMRRYSFADLVHPEDIGTLLRTSAEGGRAELRLGRRDGTYVWVSLRNSVVADTADGPRFLLTHVEDIEDRKRHELQLAHRASHDALTGLPNSAELRARLSSRLCPRPHSVGPVGAAESLDAAYERGPAHAESEAHGHAFRADGFDFEALPGGGPYDHHVHTVAPDSEIDDGTKGLAVLFCDLDGFKSINDRFGHHTGDAVLIEVARRLTTGVRDGDTVARLGGDEFVVLADGLGAADAADLAVRLRNAIIPPIRVDGRAVRVGASFGIGWASCGMSVEEVLRSADQRMYIEKRSRAKVHRRAG
>CP032698.1|AYG81439.1|4000708_4001275_+|NADH-dependent-flavin-reductase
MLQTPLTDALSALAAATPHPEGVSNDEFRAAMSRLAAGVVLVTAHDTDDGPRGEDVGMTATAFLSVSLDPPLVLVSLREGSRMDDLLAEQPLWAVSILSESQRHIAGRFAMKGRISDRLLFEDIPYSRGEASGAPLVAGALATLECRTEQRVTAGDHTLAIGRVLTANLPSAEGGPLTYFQGRYRQLG

Crispr_ID: CP032698_34

• CRISPR_ID: CP032698_34
• CRISPR_location: 4013658-4014133
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers

Consensus repeat of CP032698_34

Consensus_repeat	Method
CGCGCAGTTCCCCGCGCCCC	CRT
TTAGGGGCGCGGGGAACTGCGCGACCAGCCACGCGCGG	PILER-CR

spacers of CP032698_34

>34.1|4013678|36|CP032698|CRT
CAACCCCCTGGTCATGCGCGGACCGTGCCCGCGTCT
>34.2|4013734|35|CP032698|CRT
CAACCCCCGGTCACGTGCGGACCGTGCTCGCGTCT
>34.3|4013789|38|CP032698|CRT
TGAACCCCTCTCGATCCCGCGGACCGTGGGTGGCTGGG
>34.4|4013847|36|CP032698|CRT
AAAACCCTCGGTCACGTGCGGACCGTGCTCGCTTCT
>34.5|4013903|37|CP032698|CRT
AAAACCCTCTCAATCCCGCGGACCGTGGGTGGCTGGT
>34.6|4013960|35|CP032698|CRT
CAACCCCCGGTCACGTGCGGACCGTGCTCGCTTCT
>34.7|4014015|38|CP032698|CRT
TGAACCCCTCTCGATCCCGCGGACCGCGGGTGGCTGGT
>34.8|4014073|38|CP032698|CRT
CAAAACCCGTTTTCGTCCTCGCGCCGTGCGTGGCTGGG
>34.9|4014032|20|CP032698|PILER-CR
ACCCCTCTCGATCCCGCGGA
>34.10|4014090|20|CP032698|PILER-CR
AACCCGTTTTCGTCCTCGCG

CRISPR arrays and Neighbor proteins around CP032698_34

CRISPR arrays

The CRISPR arrays of CP032698_34

>merge|CP032698|34|4013658-4014133|CRT,PILER-CR
TCACCAGCCCCCTGCGCCCCCAACCCCCTGGTCATGCGCGGACCGTGCCCGCGTCTCGCGCAGTTCCCCGCGCCCCCAACCCCCGGTCACGTGCGGACCGTGCTCGCGTCTCGCGCAGTTCCCCGCGCCCCTGAACCCCTCTCGATCCCGCGGACCGTGGGTGGCTGGGCGCGCAGTTCCTCGCGCCCCAAAACCCTCGGTCACGTGCGGACCGTGCTCGCTTCTCGCGCAGTTCCCCGCGCCCCAAAACCCTCTCAATCCCGCGGACCGTGGGTGGCTGGTCGCGCAGTTCCCCGCGCCCCCAACCCCCGGTCACGTGCGGACCGTGCTCGCTTCTCGCGCAGTTCCCCGCGCCCCTGAACCCCTCTCGATCCCGCGGACCGCGGGTGGCTGGTCGCGCAGTTCCTCGCGCCCCCAAAACCCGTTTTCGTCCTCGCGCCGTGCGTGGCTGGGCGCGCAGTTCCCCGCGCCCCTAA

>CP032698|34|3|4013658-4014130|CRT
TCACCAGCCCCCTGCGCCCC	CAACCCCCTGGTCATGCGCGGACCGTGCCCGCGTCT
CGCGCAGTTCCCCGCGCCCC	CAACCCCCGGTCACGTGCGGACCGTGCTCGCGTCT
CGCGCAGTTCCCCGCGCCCC	TGAACCCCTCTCGATCCCGCGGACCGTGGGTGGCTGGG
CGCGCAGTTCCTCGCGCCCC	AAAACCCTCGGTCACGTGCGGACCGTGCTCGCTTCT
CGCGCAGTTCCCCGCGCCCC	AAAACCCTCTCAATCCCGCGGACCGTGGGTGGCTGGT
CGCGCAGTTCCCCGCGCCCC	CAACCCCCGGTCACGTGCGGACCGTGCTCGCTTCT
CGCGCAGTTCCCCGCGCCCC	TGAACCCCTCTCGATCCCGCGGACCGCGGGTGGCTGGT
CGCGCAGTTCCTCGCGCCCC	CAAAACCCGTTTTCGTCCTCGCGCCGTGCGTGGCTGGG
CGCGCAGTTCCCCGCGCCCC

>CP032698|34|9|4013994-4014133|PILER-CR
TCGCGCAGTTCCCCGCGCCCCTGAACCCCTCTCGATCC	CGCGGACCGCGGGTGGCTGG
TCGCGCAGTTCCTCGCGCCCCCAAAACCCGTTTTCGTC	CTCGCGCCGTGCGTGGCTGG
GCGCGCAGTTCCCCGCGCCCCTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81455.1|4020457_4021942_-|hypothetical-protein	unknown	unknown	gnl|CDD|225168
CP032698.1|AYG81448.1|4009915_4010428_-|hypothetical-protein	unknown	unknown	gnl|CDD|366181
CP032698.1|AYG81458.1|4024562_4024967_-|Putative-pyridoxine/pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|274679
CP032698.1|AYG81451.1|4016670_4017225_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81453.1|4018880_4019288_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81450.1|4012251_4013643_+|Gamma-glutamylputrescine-oxidoreductase	unknown	unknown	gnl|CDD|274522
CP032698.1|AYG81460.1|4025596_4026358_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl|CDD|234670
CP032698.1|AYG81456.1|4022017_4022974_-|putative-tRNA/rRNA-methyltransferase	unknown	unknown	gnl|CDD|223640
CP032698.1|AYG81454.1|4019321_4020053_+|Glucose-1-phosphate-cytidylyltransferase	unknown	unknown	gnl|CDD|133024
CP032698.1|AYG81445.1|4006808_4008311_+|Sensor-histidine-kinase-LiaS	unknown	unknown	gnl|CDD|226951
CP032698.1|AYG81441.1|4001952_4002528_+|General-stress-protein-16U	unknown	unknown	gnl|CDD|376767
CP032698.1|AYG81442.1|4002921_4004469_+|Transglutaminase-activating-metalloprotease	unknown	unknown	gnl|CDD|341060
CP032698.1|AYG81443.1|4004514_4005942_-|Aminopeptidase-N	unknown	unknown	gnl|CDD|341066
CP032698.1|AYG81446.1|4008513_4009068_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81459.1|4025031_4025607_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl|CDD|178851
CP032698.1|AYG81447.1|4009078_4009780_-|Pentapeptide-repeat-protein-MfpA	unknown	unknown	gnl|CDD|224276
CP032698.1|AYG81452.1|4017532_4018669_+|Trehalose-import-ATP-binding-protein-SugC	unknown	unknown	gnl|CDD|236947
CP032698.1|AYG81444.1|4006014_4006620_-|hypothetical-protein	unknown	unknown	gnl|CDD|377163
CP032698.1|AYG81457.1|4023081_4024542_-|Cysteine--tRNA-ligase	unknown	unknown	gnl|CDD|234705
CP032698.1|AYG81449.1|4011248_4012031_-|hypothetical-protein	unknown	unknown	gnl|CDD|372611

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81455.1|4020457_4021942_-|hypothetical-protein	gnl|CDD|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	5.52421e-07
CP032698.1|AYG81448.1|4009915_4010428_-|hypothetical-protein	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.50939e-15
CP032698.1|AYG81458.1|4024562_4024967_-|Putative-pyridoxine/pyridoxamine-5'-phosphate-oxidase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	1.25615e-40
CP032698.1|AYG81457.1|4023081_4024542_-|Cysteine--tRNA-ligase	gnl|CDD|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
CP032698.1|AYG81450.1|4012251_4013643_+|Gamma-glutamylputrescine-oxidoreductase	gnl|CDD|274522	TIGR03329, Phn_aa_oxid, putative aminophosphonate oxidoreductase. This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.	1.5138e-54
CP032698.1|AYG81460.1|4025596_4026358_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl|CDD|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	9.52181e-82
CP032698.1|AYG81456.1|4022017_4022974_-|putative-tRNA/rRNA-methyltransferase	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	1.69826e-76
CP032698.1|AYG81454.1|4019321_4020053_+|Glucose-1-phosphate-cytidylyltransferase	gnl|CDD|133024	cd04181, NTP_transferase, NTP_transferases catalyze the transfer of nucleotides onto phosphosugars. Nucleotidyltransferases transfer nucleotides onto phosphosugars. The enzyme family includes Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase. The products are activated sugars that are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides.	1.87239e-64
CP032698.1|AYG81445.1|4006808_4008311_+|Sensor-histidine-kinase-LiaS	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.43041e-47
CP032698.1|AYG81441.1|4001952_4002528_+|General-stress-protein-16U	gnl|CDD|376767	pfam02342, TerD, TerD domain. The TerD domain is found in TerD family proteins that include the paralogous TerD, TerA, TerE, TerF and TerZ proteins It is found in a stress response operon with TerB and TerC. TerD has a maximum of two calcium-binding sites depending on the conservation of aspartates. It has various fusions to nuclease domains, RNA binding domains, ubiquitin related domains, and metal binding domains. The ter gene products lie at the centre of membrane-linked metal recognition complexes with regulatory ramifications encompassing phosphorylation-dependent signal transduction, RNA-dependent regulation, biosynthesis of nucleoside-like metabolites and DNA processing linked to novel pathways.	1.05404e-117
CP032698.1|AYG81442.1|4002921_4004469_+|Transglutaminase-activating-metalloprotease	gnl|CDD|341060	cd09597, M4_TLP, Peptidase M4 family including thermolysin, protealysin, aureolysin, and neutral protease. This peptidase M4 family includes several endopeptidases such as thermolysin (EC 3.4.24.27), aureolysin (the extracellular metalloproteinase from Staphylococcus aureus), neutral protease from Bacillus cereus, protealysin, and bacillolysin (EC 3.4.24.28). Typically, the M4 peptidases consist of a presequence (signal sequence), a propeptide sequence, and a peptidase unit. The presequence is cleaved off during export while the propeptide has inhibitory and chaperone functions and facilitates folding. The propeptide remains attached until the peptidase is secreted and can be safely activated. All peptidases in this family bind a single catalytic zinc ion which is tetrahedrally co-ordinated by three amino acid ligands and a water molecule that forms the nucleophile on activation during catalysis. The active site is found between two sub-domains; the N-terminal domain contains the HEXXH zinc-binding motif while the helical C-terminal domain, which is unique for the family, carries the third zinc ligand. These peptidases are secreted eubacterial endopeptidases from Gram-positive or Gram-negative sources that degrade extracellular proteins and peptides for bacterial nutrition. They are selectively inhibited by Steptomyces metalloproteinase inhibitor (SMPI) as well as by phosphoramidon from Streptomyces tanashiensis. A large number of these enzymes are implicated as key factors in the pathogenesis of various diseases, including gastritis, peptic ulcer, gastric carcinoma, cholera and several types of bacterial infections, and are therefore important drug targets. Some enzymes of the family can function at extremes of temperatures, while some function in organic solvents, thus rendering them novel targets for biotechnological applications. Thermolysin is widely used as a nonspecific protease to obtain fragments for peptide sequencing. It has also been used in production of the artificial sweetener aspartame.	2.00421e-115
CP032698.1|AYG81443.1|4004514_4005942_-|Aminopeptidase-N	gnl|CDD|341066	cd09603, M1_APN_like, Peptidase M1 family similar to aminopeptidase N catalytic domain. This family contains mostly bacterial and some archaeal M1 peptidases with smilarity to the catalytic domain of aminopeptidase N (APN; CD13; alanyl aminopeptidase; EC 3.4.11.2), a type II integral membrane protease belonging to the M1 gluzincin family. APN preferentially cleaves neutral amino acids from the N-terminus of oligopeptides and, in higher eukaryotes, is present in a variety of human tissues and cell types (leukocyte, fibroblast, endothelial and epithelial cells). APN expression is dysregulated in inflammatory diseases such as chronic pain, rheumatoid arthritis, multiple sclerosis, systemic sclerosis, systemic lupus erythematosus, polymyositis/dermatomyosytis and pulmonary sarcoidosis, and is enhanced in tumor cells such as melanoma, renal, prostate, pancreas, colon, gastric and thyroid cancers. It is predominantly expressed on stem cells and on cells of the granulocytic and monocytic lineages at distinct stages of differentiation, thus considered a marker of differentiation. Thus, APN inhibition may lead to the development of anti-cancer and anti-inflammatory drugs. APNs are also present in many pathogenic bacteria and represent potential drug targets. Some APNs have been used commercially, such as one from Lactococcus lactis used in the food industry. APN also serves as a receptor for coronaviruses, although the virus receptor interaction site seems to be distinct from the enzymatic site and aminopeptidase activity is not necessary for viral infection. APNs have also been extensively studied as putative Cry toxin receptors. Cry1 proteins are pore-forming toxins that bind to the midgut epithelial cell membrane of susceptible insect larvae, causing extensive damage. Several different toxins, including Cry1Aa, Cry1Ab, Cry1Ac, Cry1Ba, Cry1Ca and Cry1Fa, have been shown to bind to APNs; however, a direct role of APN in cytotoxicity has been yet to be firmly established.	4.9099e-168
CP032698.1|AYG81459.1|4025031_4025607_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl|CDD|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.30921e-70
CP032698.1|AYG81447.1|4009078_4009780_-|Pentapeptide-repeat-protein-MfpA	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	7.3181e-16
CP032698.1|AYG81452.1|4017532_4018669_+|Trehalose-import-ATP-binding-protein-SugC	gnl|CDD|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	1.22774e-179
CP032698.1|AYG81444.1|4006014_4006620_-|hypothetical-protein	gnl|CDD|377163	pfam03928, Haem_degrading, Haem-degrading. Haem_bdg is a bacterial protein that is up-regulated in response to haemin- and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein.	1.73564e-25
CP032698.1|AYG81449.1|4011248_4012031_-|hypothetical-protein	gnl|CDD|372611	pfam13462, Thioredoxin_4, Thioredoxin.	5.5029e-22

Protein sequences

>CP032698.1|AYG81450.1|4012251_4013643_+|Gamma-glutamylputrescine-oxidoreductase
MSAINGGISFWYATDGIPAPREPLPGDRTADVVIVGGGYTGLWTAYYLKKAAPFLDITVLESRFCGYGASGRNGGWLYNGIAGRDRYAKLHGQDSAVRLQRAMNDTVAEVVRVAAEESIDADIHQGGVLEVAYGPAQLARLKAFHHAEVTFGEKDRVLLGARETAERIRVSGAVGSTWTPHGARIHPVKLLKGLAAAVEALGVTVYESTPVTEIRPQHAVTPYGTVRAPYVLRCTEGFTASLKGQRRAWLPMNSSMIATEPLGPEVWDAIGWAGRETLGDMAHAYMYAQRTADDRIALGGRGVPYRFGSRTDNDGRTQPATIEALREILVRFFPQLAGVGISHAWSGVLGVPRDWCASVTLDRTTGLGWAGGYVGSGVATANLAARTLRDLIQRDSGQSGPTDLTALPWVDHKVRAWEPEPLRWLGVRGMYAAYRAADLRELRSPRVATDRVARVADRVAGRR
>CP032698.1|AYG81449.1|4011248_4012031_-|hypothetical-protein
MGVRRFRRAVVAAVAATALGLSAAACSSGPDGPASNGSGSSGPDGPGGSGSGASARAEPSAEASPGAAALAKLPAKVEGAEIVVGDPRAPHTVSVYEDPRCPYCKHFEEGGARAVARLAAEGKVKIRYTIASFLDADPDEGGSKRAVNAMRAAVERGTFPEFHAAVFAGQPEKETDDAFTADDLLKIADKVPGLRGPTFDRAVRENTYQDFVKAAQAAFEDSGVNRSPVVLIDGKEPSGDGRAMFDADAFQKVLAESGVS
>CP032698.1|AYG81448.1|4009915_4010428_-|hypothetical-protein
MIRDASPTDIPALHRMVRELADYEKCLAEARATEERLHEALFGAHPAAFAHIAEDASGEPVGFSIWFLNFSTWRGVHGIYLEDLYVRPGARGGGHGKALLGELARICVARGYERLEWSVLNWNTPSIAFYESLGARPQDEWTVYRLTDAALTALGQSPERGERSGPGGVA
>CP032698.1|AYG81447.1|4009078_4009780_-|Pentapeptide-repeat-protein-MfpA
MVQHGGMAAARSAKKTAATAGARRVEVRLPPLAPFGAGELEPEGDYDGLEFRDLDLARQQAPSARFLDCGLYGCVLDDTRLTGARFIDSVLSGIRGVGTDLARASLRDVEVRDVRMGGVQLHGAVLERVLVKGGKIDYLNLREAELRDVVFDGCVLSEPDFGGARLTRVEFRGCELRGADFTGVRMADVDLRGVTLLDIARGVERLAGAVISPSQLLDLAPAFAAQVGVRVEA
>CP032698.1|AYG81446.1|4008513_4009068_+|hypothetical-protein
MSSRAGDGGGGGAWHHRGVLDIGYSLSRHFPDPTRIDYRRADVYTLRHDLFCGDVYLADTKADREVSTAWGWVPVLDFAWALCDTVELLDRDPLGSRAARPQYAEIDFTESSDRMLFERRFGWVDVEADWMPGDEEPLTFSHTELRRETRDFLHDLIADLTDMHEDLGENPIIWDLQARFPRIP
>CP032698.1|AYG81445.1|4006808_4008311_+|Sensor-histidine-kinase-LiaS
MRDHDGGRGAAGASPPADAEPWLPVVMHAAFFLLLGASLARFLIRHPGEPRTPWIIALSTTLALLYVLGPALGSRPTPRRLGWLGGVVATWMVLVLLAPSFAWCAVPLFYTGLRTLRPRAALVLVGVLTAFVVTAQVELSPTGFDPNLVLAPPAVAAIATAVFVQMQRQAERQRELADRQRQLIDDLLRTRRELAATERREGTLAERQRLSMEIHDTLAQGLSSQRMLLQAADRVWAADPGAARRHVRTAESIAERNLAEARRFVHDLGPADLAEGGGLDEALRALAARESVEWVGSAGAVGSAGPGGAVGDAGAAGDAGAVGLPGPGALRVRCHVDGAPNAPLPERVGPALLRIAQGALANVREHAGATTAALTLTYLGDQVVLDIADDGRGFTPGPLGVRDSASGVRGHGLPAMHARVRQLGGTLTVESAPGEGTVLSAPTPWASAPAPFAHPPVTGVGWSRPPGAPPQTPGVCPPTRPCNGWKGSAPGAPPQTPFAP
>CP032698.1|AYG81444.1|4006014_4006620_-|hypothetical-protein
MNPTAKNVTHTAGTRNKKLALTAAALAIAAAGTFGVVTANAATGTAATGAPAASTAPATATAASTGNLTTTTHLTVAAATHAAQAALDAAVKENQKVSVAVVDRDGNTLVTLRGDGAGPQSPESAVRKAYTAVSWNAPTSELAKRLAQAPNLKDIPGTLFLAGGAPVQAKGAPVAGVGVAGAPSGDLDEKFARAGVAVLNK
>CP032698.1|AYG81443.1|4004514_4005942_-|Aminopeptidase-N
MDKRPALRTAPKGRGGRRTRLAAALLAALAAASCTGGVTGGPGSAGVRDPLFPRLGNDGYDVQHYTLDLDYDPSSGRLKGGVTIVAKAVEDLSAFDLDFAGMDVESATVDDEPAAVNRAGDELTLRPEEDLTRGETFTAYVRYSGRPRTITDVDGSEEGWLRSPGGRVLALGEPTGSMTWFPSNNHPSDKATYDIRITVPDGLQAVSNGELVSRTVNKGRATFSWRTREPMATYLATVAIGPYEIDRGRTGSGVPIYSAIDPEVRRQTADVVARLPEMLAWEEKEFGPYPFSSAGLIVAPAKASGYALETQNRPVLPLDHFDATTVVHELAHQWFGDSVTPATWRDMWLNEGFAQYAEWLWSEDHSGPSAQQIFEGEYAKGGGDDIWAFPPAEPPTAADVSGRPVYVRGAMVVHKIREALGDEAFHALVRDWVRVHRHGNASTKDFVRFVDDAAGRRLTAVWDTWLYGDGKPEAS
>CP032698.1|AYG81442.1|4002921_4004469_+|Transglutaminase-activating-metalloprotease
MRTTLRAAALAASAAMVVVGVQAGSTAGATDRAAGATALDLTSAQRSDALAAAQDTAPATARKIGLGAKEKLVVRDVIKDADGTVHTRYERTFDGMPVLGGDLVVHSSKDGALKGVNKATDAKISVATTTSLKAAPTGSRKVVWAASGKPVVAYERTVTGTQPDGTPSRRDIVTDAATGAELFSHEEIETGTGTSEYSGTVTLGTTKSGSTYSLTDASRGGHSTYDLKGGSSGKGTLFTKSTDTWGNGSPSNRETAAVDAHYGAAETWDFYKTELGRNGIAGNGKAAYSRVHYGNAYVNAFWDDSCFCMTYGDGEGNQKPLTALDVAGHEMSHGLTAATAKLNYSGESGGLNEATSDIFGTSVEFFANNASDKGDYLIGEKIDINGDGTPLRYMDKPSKDGGSADYWSSGVGNKDVHYSSGPANHFFYLLSEGSGAKTINGVSYNSPTYDGSKVTGIGRVKAYKIWYKALSTYMTSTTNYKAARAATLKAAGDLYGTTSTEYKTVAAAWTAINVK
>CP032698.1|AYG81441.1|4001952_4002528_+|General-stress-protein-16U
MAVSLSKGGNVSLTKEAPGLTAVTVGLGWDVRTTTGTDFDLDASAIAVNPTGKVYSDKHFVFFNNKSTPDQTIVHTGDNTTGQGEGDDEAINVNLAGLPADVDKIVFPVSIYDAEARSQNFGQVRNAYIRIVNQAGGAEIARYDLSEDAATETAMVFGELYRNGAEWKFRAVGQGYASGLAGIAQDFGVSV
>CP032698.1|AYG81451.1|4016670_4017225_-|hypothetical-protein
MEGLSRSWLGPSGFRGWTTVGDRVAGGFEFQWALTGSGWATYRITDGVSEHSDVPSYCTDALADLLAGVAGLYGSEAPQRVSFDMEPAEVRWVLRAAGKTVTIDIHRFPDLHHSSRLPDGDGECVWSSVQPRRVVAHAVLEAAQGLLDRHGAKGYLKKWAEHPFPAAELGELRRLHRERDDCAH
>CP032698.1|AYG81452.1|4017532_4018669_+|Trehalose-import-ATP-binding-protein-SugC
MATVTFDKATRIYPGSTKPAVDGLEIEIEDGEFLVLVGPSGCGKSTSLRMLAGLEDVNGGAIRIGERDVTHLPPKDRDIAMVFQNYALYPHMTVADNMGFALKIAGVNKTEIRKKVEEAAKILDLSEYLDRKPKALSGGQRQRVAMGRAIVREPQVFLMDEPLSNLDAKLRVSTRTQIASLQRRLGITTVYVTHDQVEAMTMGDRVAVLKDGLLQQIDSPRNMYDRPANLFVAGFIGSPAMNLVEVPITDGGVKFGNSVVPVSREALTAAADRGDRTVTVGVRPEHFDIVEQGGAAAQTLTKESADAPAGLAVTVNVVEELGADGYVYGSAEVGGETKDLVVRVNGRAVPDKGTQLHVVPRPGETHVFSTSTGERLTD
>CP032698.1|AYG81453.1|4018880_4019288_+|hypothetical-protein
MTHTARRIGRTLALVLPVVLVLSGTLAVTRVNWAGNESQILTASSENVSVRAKSRAPQDVLRDALLTELQEKDPGTALTHLQREVEHRPSLAQHCMSIARALGRAAVEHYGPVKAQSYSRPVCDTSFASGVAQER
>CP032698.1|AYG81454.1|4019321_4020053_+|Glucose-1-phosphate-cytidylyltransferase
MTASTTATFPTQAVVLAGGQGSRLRPYTDDRPKPMVEIPGTGVPIIGHQLSWLAAEGVTDAVVSCGHLADVLKDWLATADLPLRVTTVVEDEPLGRGGGLKYAAASLPHPDRPWYATNGDIWTRFSLREMASFHGERDATATLALARPRIPWGAVETDAFGHITDFIESPPSPYLINAGVYVFSAAFTAMLPDVGDHERTTFPRLARERRLAGFPLPHGAYWRAIDTAKDLTEAAKELAQHGG
>CP032698.1|AYG81455.1|4020457_4021942_-|hypothetical-protein
MSVDTRTPRPGFDDQPALSMAKVDCDPAQVIVNHASFRVQLAPKPLPKPVISGTSVRRRAPVVWSGKSAPGASGLLQAVRATSAVGAGYDTGATQTIPRVAVDDTRPTPLIPGSGSGPETALLPQMRTPYGEQPYAQDEFEEFDDLDGDDVDDGSPAKRRGADPVRHAYYPGRRMNLGVVLLPLRVFLGFISVYAGLGKLCDPVYFDGGERGSMVKWLNSLHPWALAEPLRDFALQHPVGAGLTVAFLQVVVGVLTMLGLWQRVAAVFGALLSGALLVTVSWQTVRAYDAPDIIYLAAWSPLIIAGAPVYSLDARLAGEAWRKLGPRSELWELRRRVLRRGLVMTTVVVGLTLTTGALLGGAVRSTTVVTVPGPDDDPTNYLPGTPLPSETGPALAPRTTPTAVKPSAKPKSSVSPSAKASKKPKAHQSATAGTTGRPSHSAGTGGQPPSRHHTAPQAPPSTSAGPTSSGGTGSSGGSGGGGGGNRNPIGGLLG
>CP032698.1|AYG81456.1|4022017_4022974_-|putative-tRNA/rRNA-methyltransferase
MAGNSQRRNRRTSNKKGATVGSGGQRRRGLEGRGPTPPAEARKKHKKNRIATAKAKQAATRRPAPRRGGAKGASEMVVGRNPVFEALRDGVPATTLYVQQYIDNDERVREALQLAGERGNINLMEAPRAELDRMTNGLNHQGLVLQVPPYEYAEPQDLTTFAYDNGEDPLIVALDGVTDPRNLGAIVRSTSAFGGHGVVVPERRAAGMTAGAWKSSAGTAARTPVSRVTNLTRALEAYKKEGLTIVGLAADGEHTVEELEQIGGPVVIVIGSEGKGLGRLVGETCDYRVRISMPGGAESLNAGVAAGIVLYEAARRRA
>CP032698.1|AYG81457.1|4023081_4024542_-|Cysteine--tRNA-ligase
MCPEARKGRGALVLGHYPGVVTIRLYDTSARQIRDFVPLTRGCVSIYLCGATVQAAPHIGHIRSGLNFDIMRRWFEYRGYDVTFIRNVTDIDDKIIKKSAEQGRPWWSIGYANERAFNDGYTALGCLPPTYEPRATGHITEMVEMMRGLIERGHAYEADGSVYFDVRSFPEYLALSNQDIDDLRQPAEEGITGKRDPRDFAMWKASKPGEPDWETPWGRGRPGWHLECSAMAHKYLGSAFDIHGGGLDLIFPHHENEIAQAKAFGDDFASYWVHNAWVTMSGEKMSKSLGNSVLVSEMVKQWRPIVLRYYLGTPHYRSMIEYSEDALREAESAFARIEGFIQRVVEKAGGVVEPAAEVPPAFAEAMDDDLGVPGALAIVHTTVRQGNSALAADDKEAAIGRLAEVRAMLGVLGLDPLDPQWAQEGERGEDLHGAVDTLVRLVLEQREAARARKDWATADAIRDQLTQSGLVVEDSPSGPRWTLGPR
>CP032698.1|AYG81458.1|4024562_4024967_-|Putative-pyridoxine/pyridoxamine-5'-phosphate-oxidase
MSAELSDKLKELLDSPVFVNIATIQPDGSPQVSPVWVKRDGNDVLISTTVDRRKEKNLRRDPRVSVLLQRFDSPYEYAEIRGTAELTTEGGQELIDELSMKYSGKTYREFNPASVDDAPRVVVRITPRKIVGML
>CP032698.1|AYG81459.1|4025031_4025607_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MASEALDTGDALDSGDVLDTGDALDTRSVAPRPVIPQVGIGTDVHAFERGRELWCAGLLWEGEEYGLAGHSDGDVAAHAACDALFSAAGVGDLGAHFGTDRPEWSGASGVTLLAEAARIVRAEGFEIGNVAVQVIGVRPKIGKRREAAQKALSAAAGAPVAVSGTTTDGLGLTGRAEGLAAIATAMVYRMP
>CP032698.1|AYG81460.1|4025596_4026358_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MSDESRTFRTAAVIPAAGRGVRLGPGAPKALRALNGTPMLIHAVRAMAASRAVSLVVVVAPPDGEAEVKNLLAEHALPGGPPGSSWGRTEYLVVPGGESRQESVRLGLDALPPGFDAVLVHDAARPLVPVDTVDAVIEAVRDGAPAVVPALPLADTVKQVEPRADGSPEPVLATPDRATLRAVQTPQGFDHDTLVRAHATVTGSVTDDAGMIERLGLPVVVVPGHEEAFKVTRPLDLVLAEAVLARRRANDGF

Crispr_ID: CP032698_35

• CRISPR_ID: CP032698_35
• CRISPR_location: 4020221-4020362
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_35

Consensus_repeat	Method
AGGGGCGCGGGGAACTGCGCGAGAAGCG	PILER-CR

spacers of CP032698_35

>35.1|4020249|30|CP032698|PILER-CR
ACCCGCGGCCCGCAGCCGAAAACGGGTTTT
>35.2|4020307|28|CP032698|PILER-CR
GGCACGGTCCGCAGGTTCGAGAGGGGTT

CRISPR arrays and Neighbor proteins around CP032698_35

CRISPR arrays

The CRISPR arrays of CP032698_35

>merge|CP032698|35|4020221-4020362|PILER-CR
AGGGGCGCGGGGAACTGCGCGAGAAGCCACCCGCGGCCCGCAGCCGAAAACGGGTTTTAGGGGCGCGAGGAACTGCGCGAGAAGCGGGCACGGTCCGCAGGTTCGAGAGGGGTTAGGGGCGCGGGGAACTGCGCGAGAAGCG

>CP032698|35|10|4020221-4020362|PILER-CR
AGGGGCGCGGGGAACTGCGCGAGAAGCC	ACCCGCGGCCCGCAGCCGAAAACGGGTTTT
AGGGGCGCGAGGAACTGCGCGAGAAGCG	GGCACGGTCCGCAGGTTCGAGAGGGGTT
AGGGGCGCGGGGAACTGCGCGAGAAGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81455.1|4020457_4021942_-|hypothetical-protein	unknown	unknown	gnl|CDD|225168
CP032698.1|AYG81448.1|4009915_4010428_-|hypothetical-protein	unknown	unknown	gnl|CDD|366181
CP032698.1|AYG81458.1|4024562_4024967_-|Putative-pyridoxine/pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|274679
CP032698.1|AYG81451.1|4016670_4017225_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81461.1|4026622_4027105_-|RNA-polymerase-binding-transcription-factor-CarD	unknown	unknown	gnl|CDD|224248
CP032698.1|AYG81462.1|4027719_4028388_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81450.1|4012251_4013643_+|Gamma-glutamylputrescine-oxidoreductase	unknown	unknown	gnl|CDD|274522
CP032698.1|AYG81460.1|4025596_4026358_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl|CDD|234670
CP032698.1|AYG81456.1|4022017_4022974_-|putative-tRNA/rRNA-methyltransferase	unknown	unknown	gnl|CDD|223640
CP032698.1|AYG81454.1|4019321_4020053_+|Glucose-1-phosphate-cytidylyltransferase	unknown	unknown	gnl|CDD|133024
CP032698.1|AYG81463.1|4028553_4029234_-|Sensory-transduction-protein-regX3	unknown	unknown	gnl|CDD|223816
CP032698.1|AYG81464.1|4029230_4030541_-|Signal-transduction-histidine-kinase-senX3	unknown	unknown	gnl|CDD|274368
CP032698.1|AYG81453.1|4018880_4019288_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81457.1|4023081_4024542_-|Cysteine--tRNA-ligase	unknown	unknown	gnl|CDD|234705
CP032698.1|AYG81446.1|4008513_4009068_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81459.1|4025031_4025607_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl|CDD|178851
CP032698.1|AYG81449.1|4011248_4012031_-|hypothetical-protein	unknown	unknown	gnl|CDD|372611
CP032698.1|AYG81452.1|4017532_4018669_+|Trehalose-import-ATP-binding-protein-SugC	unknown	unknown	gnl|CDD|236947
CP032698.1|AYG81445.1|4006808_4008311_+|Sensor-histidine-kinase-LiaS	unknown	unknown	gnl|CDD|226951
CP032698.1|AYG81447.1|4009078_4009780_-|Pentapeptide-repeat-protein-MfpA	unknown	unknown	gnl|CDD|224276

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81455.1|4020457_4021942_-|hypothetical-protein	gnl|CDD|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	5.52421e-07
CP032698.1|AYG81448.1|4009915_4010428_-|hypothetical-protein	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	4.50939e-15
CP032698.1|AYG81458.1|4024562_4024967_-|Putative-pyridoxine/pyridoxamine-5'-phosphate-oxidase	gnl|CDD|274679	TIGR03618, Rv1155_F420, PPOX class probable F420-dependent enzyme. A Genome Properties metabolic reconstruction for F420 biosynthesis shows that slightly over 10 percent of all prokaryotes with fully sequenced genomes, including about two thirds of the Actinomyces, make F420. The Partial Phylogenetic Profiling algorithm identifies this members of this protein family as high-scoring proteins to the F420 biosynthesis profile. A member of this family, Rv1155, was crytallized after expression in Escherichia coli, which does not synthesize F420; the crystal structure shown to resemble FMN-binding proteins, but with a recognizable empty cleft corresponding to, yet differing profounding from, the FMN site of pyridoxine 5'-phosphate oxidase. We propose that this protein family consists of F420-binding enzymes. [Unknown function, Enzymes of unknown specificity].	1.25615e-40
CP032698.1|AYG81450.1|4012251_4013643_+|Gamma-glutamylputrescine-oxidoreductase	gnl|CDD|274522	TIGR03329, Phn_aa_oxid, putative aminophosphonate oxidoreductase. This clade of sequences are members of the pfam01266 family of FAD-dependent oxidoreductases. Characterized proteins within this family include glycerol-3-phosphate dehydrogenase (1.1.99.5), sarcosine oxidase beta subunit (1.5.3.1) and a number of deaminating amino acid oxidases (1.4.-.-). These genes have been consistently observed in a genomic context including genes for the import and catabolism of 2-aminoethylphosphonate (AEP). If the substrate of this oxidoreductase is AEP itself, then it is probably acting in the manner of a deaminating oxidase, resulting in the same product (phosphonoacetaldehyde) as the transaminase PhnW (TIGR02326), but releasing ammonia instead of coupling to pyruvate:alanine. Alternatively, it is reasonable to suppose that the various ABC cassette transporters which are also associated with these loci allow the import of phosphonates closely related to AEP which may not be substrates for PhnW.	1.5138e-54
CP032698.1|AYG81460.1|4025596_4026358_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl|CDD|234670	PRK00155, ispD, D-ribitol-5-phosphate cytidylyltransferase.	9.52181e-82
CP032698.1|AYG81456.1|4022017_4022974_-|putative-tRNA/rRNA-methyltransferase	gnl|CDD|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	1.69826e-76
CP032698.1|AYG81454.1|4019321_4020053_+|Glucose-1-phosphate-cytidylyltransferase	gnl|CDD|133024	cd04181, NTP_transferase, NTP_transferases catalyze the transfer of nucleotides onto phosphosugars. Nucleotidyltransferases transfer nucleotides onto phosphosugars. The enzyme family includes Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase. The products are activated sugars that are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides.	1.87239e-64
CP032698.1|AYG81463.1|4028553_4029234_-|Sensory-transduction-protein-regX3	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	2.68296e-94
CP032698.1|AYG81464.1|4029230_4030541_-|Signal-transduction-histidine-kinase-senX3	gnl|CDD|274368	TIGR02966, Phosphate_regulon_sensor_protein_PhoR, phosphate regulon sensor kinase PhoR. Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems].	7.79145e-77
CP032698.1|AYG81461.1|4026622_4027105_-|RNA-polymerase-binding-transcription-factor-CarD	gnl|CDD|224248	COG1329, COG1329, Transcriptional regulators, similar to M. xanthus CarD [Transcription].	1.09043e-69
CP032698.1|AYG81457.1|4023081_4024542_-|Cysteine--tRNA-ligase	gnl|CDD|234705	PRK00260, cysS, cysteinyl-tRNA synthetase; Validated.	0
CP032698.1|AYG81459.1|4025031_4025607_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl|CDD|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	1.30921e-70
CP032698.1|AYG81449.1|4011248_4012031_-|hypothetical-protein	gnl|CDD|372611	pfam13462, Thioredoxin_4, Thioredoxin.	5.5029e-22
CP032698.1|AYG81452.1|4017532_4018669_+|Trehalose-import-ATP-binding-protein-SugC	gnl|CDD|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	1.22774e-179
CP032698.1|AYG81445.1|4006808_4008311_+|Sensor-histidine-kinase-LiaS	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	1.43041e-47
CP032698.1|AYG81447.1|4009078_4009780_-|Pentapeptide-repeat-protein-MfpA	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	7.3181e-16

Protein sequences

>CP032698.1|AYG81454.1|4019321_4020053_+|Glucose-1-phosphate-cytidylyltransferase
MTASTTATFPTQAVVLAGGQGSRLRPYTDDRPKPMVEIPGTGVPIIGHQLSWLAAEGVTDAVVSCGHLADVLKDWLATADLPLRVTTVVEDEPLGRGGGLKYAAASLPHPDRPWYATNGDIWTRFSLREMASFHGERDATATLALARPRIPWGAVETDAFGHITDFIESPPSPYLINAGVYVFSAAFTAMLPDVGDHERTTFPRLARERRLAGFPLPHGAYWRAIDTAKDLTEAAKELAQHGG
>CP032698.1|AYG81453.1|4018880_4019288_+|hypothetical-protein
MTHTARRIGRTLALVLPVVLVLSGTLAVTRVNWAGNESQILTASSENVSVRAKSRAPQDVLRDALLTELQEKDPGTALTHLQREVEHRPSLAQHCMSIARALGRAAVEHYGPVKAQSYSRPVCDTSFASGVAQER
>CP032698.1|AYG81452.1|4017532_4018669_+|Trehalose-import-ATP-binding-protein-SugC
MATVTFDKATRIYPGSTKPAVDGLEIEIEDGEFLVLVGPSGCGKSTSLRMLAGLEDVNGGAIRIGERDVTHLPPKDRDIAMVFQNYALYPHMTVADNMGFALKIAGVNKTEIRKKVEEAAKILDLSEYLDRKPKALSGGQRQRVAMGRAIVREPQVFLMDEPLSNLDAKLRVSTRTQIASLQRRLGITTVYVTHDQVEAMTMGDRVAVLKDGLLQQIDSPRNMYDRPANLFVAGFIGSPAMNLVEVPITDGGVKFGNSVVPVSREALTAAADRGDRTVTVGVRPEHFDIVEQGGAAAQTLTKESADAPAGLAVTVNVVEELGADGYVYGSAEVGGETKDLVVRVNGRAVPDKGTQLHVVPRPGETHVFSTSTGERLTD
>CP032698.1|AYG81451.1|4016670_4017225_-|hypothetical-protein
MEGLSRSWLGPSGFRGWTTVGDRVAGGFEFQWALTGSGWATYRITDGVSEHSDVPSYCTDALADLLAGVAGLYGSEAPQRVSFDMEPAEVRWVLRAAGKTVTIDIHRFPDLHHSSRLPDGDGECVWSSVQPRRVVAHAVLEAAQGLLDRHGAKGYLKKWAEHPFPAAELGELRRLHRERDDCAH
>CP032698.1|AYG81450.1|4012251_4013643_+|Gamma-glutamylputrescine-oxidoreductase
MSAINGGISFWYATDGIPAPREPLPGDRTADVVIVGGGYTGLWTAYYLKKAAPFLDITVLESRFCGYGASGRNGGWLYNGIAGRDRYAKLHGQDSAVRLQRAMNDTVAEVVRVAAEESIDADIHQGGVLEVAYGPAQLARLKAFHHAEVTFGEKDRVLLGARETAERIRVSGAVGSTWTPHGARIHPVKLLKGLAAAVEALGVTVYESTPVTEIRPQHAVTPYGTVRAPYVLRCTEGFTASLKGQRRAWLPMNSSMIATEPLGPEVWDAIGWAGRETLGDMAHAYMYAQRTADDRIALGGRGVPYRFGSRTDNDGRTQPATIEALREILVRFFPQLAGVGISHAWSGVLGVPRDWCASVTLDRTTGLGWAGGYVGSGVATANLAARTLRDLIQRDSGQSGPTDLTALPWVDHKVRAWEPEPLRWLGVRGMYAAYRAADLRELRSPRVATDRVARVADRVAGRR
>CP032698.1|AYG81449.1|4011248_4012031_-|hypothetical-protein
MGVRRFRRAVVAAVAATALGLSAAACSSGPDGPASNGSGSSGPDGPGGSGSGASARAEPSAEASPGAAALAKLPAKVEGAEIVVGDPRAPHTVSVYEDPRCPYCKHFEEGGARAVARLAAEGKVKIRYTIASFLDADPDEGGSKRAVNAMRAAVERGTFPEFHAAVFAGQPEKETDDAFTADDLLKIADKVPGLRGPTFDRAVRENTYQDFVKAAQAAFEDSGVNRSPVVLIDGKEPSGDGRAMFDADAFQKVLAESGVS
>CP032698.1|AYG81448.1|4009915_4010428_-|hypothetical-protein
MIRDASPTDIPALHRMVRELADYEKCLAEARATEERLHEALFGAHPAAFAHIAEDASGEPVGFSIWFLNFSTWRGVHGIYLEDLYVRPGARGGGHGKALLGELARICVARGYERLEWSVLNWNTPSIAFYESLGARPQDEWTVYRLTDAALTALGQSPERGERSGPGGVA
>CP032698.1|AYG81447.1|4009078_4009780_-|Pentapeptide-repeat-protein-MfpA
MVQHGGMAAARSAKKTAATAGARRVEVRLPPLAPFGAGELEPEGDYDGLEFRDLDLARQQAPSARFLDCGLYGCVLDDTRLTGARFIDSVLSGIRGVGTDLARASLRDVEVRDVRMGGVQLHGAVLERVLVKGGKIDYLNLREAELRDVVFDGCVLSEPDFGGARLTRVEFRGCELRGADFTGVRMADVDLRGVTLLDIARGVERLAGAVISPSQLLDLAPAFAAQVGVRVEA
>CP032698.1|AYG81446.1|4008513_4009068_+|hypothetical-protein
MSSRAGDGGGGGAWHHRGVLDIGYSLSRHFPDPTRIDYRRADVYTLRHDLFCGDVYLADTKADREVSTAWGWVPVLDFAWALCDTVELLDRDPLGSRAARPQYAEIDFTESSDRMLFERRFGWVDVEADWMPGDEEPLTFSHTELRRETRDFLHDLIADLTDMHEDLGENPIIWDLQARFPRIP
>CP032698.1|AYG81445.1|4006808_4008311_+|Sensor-histidine-kinase-LiaS
MRDHDGGRGAAGASPPADAEPWLPVVMHAAFFLLLGASLARFLIRHPGEPRTPWIIALSTTLALLYVLGPALGSRPTPRRLGWLGGVVATWMVLVLLAPSFAWCAVPLFYTGLRTLRPRAALVLVGVLTAFVVTAQVELSPTGFDPNLVLAPPAVAAIATAVFVQMQRQAERQRELADRQRQLIDDLLRTRRELAATERREGTLAERQRLSMEIHDTLAQGLSSQRMLLQAADRVWAADPGAARRHVRTAESIAERNLAEARRFVHDLGPADLAEGGGLDEALRALAARESVEWVGSAGAVGSAGPGGAVGDAGAAGDAGAVGLPGPGALRVRCHVDGAPNAPLPERVGPALLRIAQGALANVREHAGATTAALTLTYLGDQVVLDIADDGRGFTPGPLGVRDSASGVRGHGLPAMHARVRQLGGTLTVESAPGEGTVLSAPTPWASAPAPFAHPPVTGVGWSRPPGAPPQTPGVCPPTRPCNGWKGSAPGAPPQTPFAP
>CP032698.1|AYG81455.1|4020457_4021942_-|hypothetical-protein
MSVDTRTPRPGFDDQPALSMAKVDCDPAQVIVNHASFRVQLAPKPLPKPVISGTSVRRRAPVVWSGKSAPGASGLLQAVRATSAVGAGYDTGATQTIPRVAVDDTRPTPLIPGSGSGPETALLPQMRTPYGEQPYAQDEFEEFDDLDGDDVDDGSPAKRRGADPVRHAYYPGRRMNLGVVLLPLRVFLGFISVYAGLGKLCDPVYFDGGERGSMVKWLNSLHPWALAEPLRDFALQHPVGAGLTVAFLQVVVGVLTMLGLWQRVAAVFGALLSGALLVTVSWQTVRAYDAPDIIYLAAWSPLIIAGAPVYSLDARLAGEAWRKLGPRSELWELRRRVLRRGLVMTTVVVGLTLTTGALLGGAVRSTTVVTVPGPDDDPTNYLPGTPLPSETGPALAPRTTPTAVKPSAKPKSSVSPSAKASKKPKAHQSATAGTTGRPSHSAGTGGQPPSRHHTAPQAPPSTSAGPTSSGGTGSSGGSGGGGGGNRNPIGGLLG
>CP032698.1|AYG81456.1|4022017_4022974_-|putative-tRNA/rRNA-methyltransferase
MAGNSQRRNRRTSNKKGATVGSGGQRRRGLEGRGPTPPAEARKKHKKNRIATAKAKQAATRRPAPRRGGAKGASEMVVGRNPVFEALRDGVPATTLYVQQYIDNDERVREALQLAGERGNINLMEAPRAELDRMTNGLNHQGLVLQVPPYEYAEPQDLTTFAYDNGEDPLIVALDGVTDPRNLGAIVRSTSAFGGHGVVVPERRAAGMTAGAWKSSAGTAARTPVSRVTNLTRALEAYKKEGLTIVGLAADGEHTVEELEQIGGPVVIVIGSEGKGLGRLVGETCDYRVRISMPGGAESLNAGVAAGIVLYEAARRRA
>CP032698.1|AYG81457.1|4023081_4024542_-|Cysteine--tRNA-ligase
MCPEARKGRGALVLGHYPGVVTIRLYDTSARQIRDFVPLTRGCVSIYLCGATVQAAPHIGHIRSGLNFDIMRRWFEYRGYDVTFIRNVTDIDDKIIKKSAEQGRPWWSIGYANERAFNDGYTALGCLPPTYEPRATGHITEMVEMMRGLIERGHAYEADGSVYFDVRSFPEYLALSNQDIDDLRQPAEEGITGKRDPRDFAMWKASKPGEPDWETPWGRGRPGWHLECSAMAHKYLGSAFDIHGGGLDLIFPHHENEIAQAKAFGDDFASYWVHNAWVTMSGEKMSKSLGNSVLVSEMVKQWRPIVLRYYLGTPHYRSMIEYSEDALREAESAFARIEGFIQRVVEKAGGVVEPAAEVPPAFAEAMDDDLGVPGALAIVHTTVRQGNSALAADDKEAAIGRLAEVRAMLGVLGLDPLDPQWAQEGERGEDLHGAVDTLVRLVLEQREAARARKDWATADAIRDQLTQSGLVVEDSPSGPRWTLGPR
>CP032698.1|AYG81458.1|4024562_4024967_-|Putative-pyridoxine/pyridoxamine-5'-phosphate-oxidase
MSAELSDKLKELLDSPVFVNIATIQPDGSPQVSPVWVKRDGNDVLISTTVDRRKEKNLRRDPRVSVLLQRFDSPYEYAEIRGTAELTTEGGQELIDELSMKYSGKTYREFNPASVDDAPRVVVRITPRKIVGML
>CP032698.1|AYG81459.1|4025031_4025607_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MASEALDTGDALDSGDVLDTGDALDTRSVAPRPVIPQVGIGTDVHAFERGRELWCAGLLWEGEEYGLAGHSDGDVAAHAACDALFSAAGVGDLGAHFGTDRPEWSGASGVTLLAEAARIVRAEGFEIGNVAVQVIGVRPKIGKRREAAQKALSAAAGAPVAVSGTTTDGLGLTGRAEGLAAIATAMVYRMP
>CP032698.1|AYG81460.1|4025596_4026358_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MSDESRTFRTAAVIPAAGRGVRLGPGAPKALRALNGTPMLIHAVRAMAASRAVSLVVVVAPPDGEAEVKNLLAEHALPGGPPGSSWGRTEYLVVPGGESRQESVRLGLDALPPGFDAVLVHDAARPLVPVDTVDAVIEAVRDGAPAVVPALPLADTVKQVEPRADGSPEPVLATPDRATLRAVQTPQGFDHDTLVRAHATVTGSVTDDAGMIERLGLPVVVVPGHEEAFKVTRPLDLVLAEAVLARRRANDGF
>CP032698.1|AYG81461.1|4026622_4027105_-|RNA-polymerase-binding-transcription-factor-CarD
MTFKVGDTVVYPHHGAALIEAIETRQIKGVDKTYLVLKVAQGDLTVRVPADNAEFVGVRDVVGQDGLDRVFEVLRAPFAEEPTNWSRRYKANLEKLASGDVIKVAEVVRDLWRRERERGLSAGEKRMLAKARQILVSELALAENTNEDKAEALLDEVLAS
>CP032698.1|AYG81462.1|4027719_4028388_+|hypothetical-protein
MSRSLRRGALAASAIAFSLASLSACAAGNGAQTLEVKADNAYVTVGDIKVQNATVVTQPKADAEGPAVVAATLFNNGGDPQTLDAVQVGSATVKLSPAKGAGAITVPAHGSVVLGGKDNASAVVDNGREAAKNGDAQKVTFQFSKAGAVSLQAFVVPATSYFEGVGPSKLPKPKESPEAGPTGKASGSPSGGASTSATPNTGTVSGKPAGSGSPSHTATTGH
>CP032698.1|AYG81463.1|4028553_4029234_-|Sensory-transduction-protein-regX3
MTRVLVVEDEESFSDALSYMLRKEGFEVAVAATGPDGLDEFERNGADLVLLDLMLPGLPGTEVCRQLRGRSNVPVIMVTAKDSEIDKVVGLEIGADDYVTKPFSSRELVARIRAVLRRRGEPEEVAPAALEAGPVRMDVDRHVVTVSGGKVDLPLKEFDLLEMLLRNAGRVLTRMQLIDRVWGADYVGDTKTLDVHVKRLRAKIEPDPGAPRYLVTVRGLGYKFEP
>CP032698.1|AYG81464.1|4029230_4030541_-|Signal-transduction-histidine-kinase-senX3
MDVNAAVAALAAIAGVCTGVIAMLAFRWSERDQARPTRSSLHTDAVLPPGVDTVLSVLRSSAVVLDESDSVVKASSAAYALGLVRGGKLAVEPMLHMARDTRRDGEIRQVELDLPRRGTGRGEALAVSARVAPLGSRLVLLLVEDLTEARRIEAVRRDFVANVSHELKTPTGALSLLSEAVMDASDDPEAVTRFAGRMQIEATRLTNLVQELIDLSRVQNDDPLEDAEPVRVDELVAEAMDRSRHPASTKQITMAAGGTADLYVWGNRGQLAAALGNLVENAVNYSPARTRVGIAGRRIAAPGGGGTSQAFGTGGLIEIAVTDQGIGISEKDRERVFERFYRVDPARSRATGGTGLGLAIVKHVAASHGGEVTVWSSEGQGSTFTLRLPEAGAVRDRASARRGPAPVDEDDDVPYETFSSAVPHSPAIVPAPEVLP

Crispr_ID: CP032698_36

• CRISPR_ID: CP032698_36
• CRISPR_location: 4047341-4047443
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_36

Consensus_repeat	Method
CCCCCGCACGGGCGGGCGGGTGGGA	CRISPRCasFinder

spacers of CP032698_36

>36.1|4047366|53|CP032698|CRISPRCasFinder
GGGTGGGAAAGCCCCGCCGGGGTCCGGGGCGGAGCCCCGGGGGCCGCACCCTC

CRISPR arrays and Neighbor proteins around CP032698_36

CRISPR arrays

The CRISPR arrays of CP032698_36

>merge|CP032698|36|4047341-4047443|CRISPRCasFinder
CCCTCGCACCCCCGCACGGGCGGGCGGGTGGGAAAGCCCCGCCGGGGTCCGGGGCGGAGCCCCGGGGGCCGCACCCTCGCACCCCCCGCACGGGCGGGCGGGT

>CP032698|36|27|4047341-4047443|CRISPRCasFinder
CCCTCGCACCCCCGCACGGGCGGGC	GGGTGGGAAAGCCCCGCCGGGGTCCGGGGCGGAGCCCCGGGGGCCGCACCCTC
GCACCCCCCGCACGGGCGGGCGGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81489.1|4054149_4054767_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81487.1|4052322_4053588_+|hypothetical-protein	unknown	unknown	gnl|CDD|369272
CP032698.1|AYG81475.1|4040075_4040531_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81474.1|4037753_4039871_+|hypothetical-protein	unknown	unknown	gnl|CDD|224588
CP032698.1|AYG81478.1|4041883_4043047_+|hypothetical-protein	unknown	unknown	gnl|CDD|372031
CP032698.1|AYG81476.1|4040616_4041534_+|hypothetical-protein	unknown	unknown	gnl|CDD|378140
CP032698.1|AYG81473.1|4037143_4037695_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81484.1|4048059_4049403_-|D-inositol-3-phosphate-glycosyltransferase	unknown	unknown	gnl|CDD|132490
CP032698.1|AYG81491.1|4055287_4055674_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81486.1|4050958_4052017_+|putative-endopeptidase	unknown	unknown	gnl|CDD|223862
CP032698.1|AYG81482.1|4045812_4047093_+|Multidrug-resistance-protein-MdtH	unknown	unknown	gnl|CDD|340887
CP032698.1|AYG81490.1|4054789_4055197_-|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG81483.1|4047454_4047946_-|hypothetical-protein	unknown	unknown	gnl|CDD|371210
CP032698.1|AYG81488.1|4053668_4054013_-|hypothetical-protein	unknown	unknown	gnl|CDD|378483
CP032698.1|AYG81492.1|4055837_4056809_+|2-haloacrylate-reductase	unknown	unknown	gnl|CDD|176206
CP032698.1|AYG81477.1|4041530_4041887_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81481.1|4044851_4045613_-|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl|CDD|184519
CP032698.1|AYG81485.1|4049661_4050573_+|hypothetical-protein	unknown	unknown	gnl|CDD|237057
CP032698.1|AYG81480.1|4043498_4044797_+|Putative-defective-protein-IntQ	unknown	unknown	gnl|CDD|271189
CP032698.1|AYG81479.1|4043227_4043461_+|hypothetical-protein	unknown	unknown	gnl|CDD|378935

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81481.1|4044851_4045613_-|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	gnl|CDD|184519	PRK14120, gpmA, phosphoglyceromutase; Provisional.	0
CP032698.1|AYG81487.1|4052322_4053588_+|hypothetical-protein	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	2.27607e-37
CP032698.1|AYG81474.1|4037753_4039871_+|hypothetical-protein	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	0.000798972
CP032698.1|AYG81478.1|4041883_4043047_+|hypothetical-protein	gnl|CDD|372031	pfam12307, DUF3631, Protein of unknown function (DUF3631). This protein is found in bacteria. Proteins in this family are typically between 180 to 701 amino acids in length.	6.49838e-82
CP032698.1|AYG81485.1|4049661_4050573_+|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.00638886
CP032698.1|AYG81484.1|4048059_4049403_-|D-inositol-3-phosphate-glycosyltransferase	gnl|CDD|132490	TIGR03449, mycothiol_MshA, D-inositol-3-phosphate glycosyltransferase. Members of this protein family, found exclusively in the Actinobacteria, are MshA, the glycosyltransferase of mycothiol biosynthesis. Mycothiol replaces glutathione in these species.	0
CP032698.1|AYG81486.1|4050958_4052017_+|putative-endopeptidase	gnl|CDD|223862	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane].	8.2857e-22
CP032698.1|AYG81482.1|4045812_4047093_+|Multidrug-resistance-protein-MdtH	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.38842e-88
CP032698.1|AYG81490.1|4054789_4055197_-|putative-HTH-type-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.36082e-14
CP032698.1|AYG81483.1|4047454_4047946_-|hypothetical-protein	gnl|CDD|371210	pfam10722, YbjN, Putative bacterial sensory transduction regulator. YbjN is a putative sensory transduction regulator protein found in Proteobacteria. As it is a multi-copy suppressor of the coenzyme A-associated temperature sensitivity in temperature-sensitive mutant strains of Escherichia coli the suggestion is that it both helps CoA-A1 and possibly works as a general stabilizer for some other unstable proteins. This family was expanded to subsume other related families: DUF1790, DUF1821 and DUF2596.	3.78727e-18
CP032698.1|AYG81492.1|4055837_4056809_+|2-haloacrylate-reductase	gnl|CDD|176206	cd08244, MDR_enoyl_red, Possible enoyl reductase. Member identified as possible enoyl reductase of the MDR family. 2-enoyl thioester reductase (ETR) catalyzes the NADPH-dependent dependent conversion of trans-2-enoyl acyl carrier protein/coenzyme A (ACP/CoA) to acyl-(ACP/CoA) in fatty acid synthesis. 2-enoyl thioester reductase activity has been linked in Candida tropicalis as essential in maintaining mitiochondrial respiratory function. This ETR family is a part of the medium chain dehydrogenase/reductase family, but lack the zinc coordination sites characteristic of the alcohol dehydrogenases in this family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. Candida tropicalis enoyl thioester reductase (Etr1p) catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis. Etr1p forms homodimers, with each subunit containing a nucleotide-binding Rossmann fold domain and a catalytic domain.	2.4226e-103
CP032698.1|AYG81476.1|4040616_4041534_+|hypothetical-protein	gnl|CDD|378140	pfam09250, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal. Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities.	8.14746e-45
CP032698.1|AYG81488.1|4053668_4054013_-|hypothetical-protein	gnl|CDD|378483	pfam10724, DUF2516, Protein of unknown function (DUF2516). This family is conserved in Actinobacteria. The function is not known.	1.01184e-25
CP032698.1|AYG81480.1|4043498_4044797_+|Putative-defective-protein-IntQ	gnl|CDD|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	8.05206e-29
CP032698.1|AYG81479.1|4043227_4043461_+|hypothetical-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	3.10713e-10

Protein sequences

>CP032698.1|AYG81482.1|4045812_4047093_+|Multidrug-resistance-protein-MdtH
MSIATLRRAARETVSGLPREFWWLWTSTLINRLGAFVATFMALYLTLDRGYSASYAGLVASVHGLGGVISAIAGGVMTDRLGRRPTLVIAQTSTALSVALLGFMTDPAAIVGVAFLVGMASNASRPAVQAMMADIVKPEDRVRAFSLNYWAINLGFAVSSMAAGFIAQYSYLAGFLGEATLTLICAVVVFLKLPESRPVRTAEEKVAEPSVGIGTVLRDGRFMGVVGLSFLISLIFQQGYVGLPIAMGTDGFSSADFGLAIAVNGILIVAVQLPITRYTQQRDPRQLLIVSALLAGYGFGLTAFAGSVAMYALTICVWTLAEIINAPTQTGLVVRLSPLHGRGRYQGVYTMSWSVAALLAPLLSGYVIDHFGAGWLWGTCAVLGTGTAVGYWALMRSLTATPAPANPANPADAARVRVEVRTDSGV
>CP032698.1|AYG81481.1|4044851_4045613_-|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase
MADAPYKLILLRHGESEWNEKNLFTGWVDVNLTPKGEKEAARGGELLKDAGLLPDVLHTSLQKRAIRTAQLALESADRHWIPVHRSWRLNERHYGALQGKDKAQTLAEFGEEQFMLWRRSYDTPPPALEDGTEFSQSDDARYATIPPELRPRTECLKDVVTRMLPYWYDGIVPDLLDGKTVLVAAHGNSLRALVKHLDGISDADIAGLNIPTGIPLVYELDTDFKPVNPGGTYLDPDAAAAAIEAVKNQGKKK
>CP032698.1|AYG81480.1|4043498_4044797_+|Putative-defective-protein-IntQ
MALPSPSPKGTAFMAGHIQDRWYKTETDANGKTTRVKSDRYGTGMRYRARYIAPDGTEKSKSFPDGKKRLAEEWLARIEADMSRGQYIDPKATRMTFQEFGEKWLASQSGDPNTKASMTSQLRLHAFPRIGARSLGAFQPSHIREFVTQLEGSGMSGSYARVIFSNVRAILSAAVEDGYMPRNPCTSRTVTLPEMGARRVVPWLPERVFAVRSAMVDRFRPMVDVGAGCGMRQGEILGLSVEELDFGNGTLHVVQQLKLSLSQPVFAPPKGGKLRDVPLPEPVADALREHMKLFPPVEITLPWMRAGGQPVTKRLIFTGPLGSHVWRTSLNEDHWKPALAKVGVIPKAKSREHTAAREHGMHALRHFYASVLLDAGESIKAVSEYLGHSDPGLTLKVYAHLMPSSRDRARKALGRALRPQDPPASRPTDGPE
>CP032698.1|AYG81479.1|4043227_4043461_+|hypothetical-protein
MRPPPAVADTLRNGIPDRYLTPDDIAAIFEVPKETVYQWRKKRVGPPGFRIGKHVRYDPAEVLAYVAERKGADRAAA
>CP032698.1|AYG81478.1|4041883_4043047_+|hypothetical-protein
MTTTPPAPSIDGAALLDEVEAFHRRFNIFPSEAAYVAVALWDAHAHLLDCFDSTPRLAFLSPEPGSGKSRALEIVETLVPRPMVAVNASAAALFRAVSGAEGRPTILFDEIDTVFGPKAGDNEELRGFLNAGHRRTGVTYRCVGDSQTVTPFPSYAAVAVAGLGSLPDTILTRAVIIRMRRRARNEKVEPFRARLHEQEGHALRDRLAEWAEQARGWVMGAWPEMPDGVSDRPADVWEGLLSIADAAGGDWPKRARQACLTLVEASRANDKGSLGIRLLTDLRDHVLIGIDRLPTVAILDRLNALDDAPWADLNGRPLDNRRLSKMLSDYVTADGGPIASRNIRTSGGILKGFFAEDLTDAWARYCPSPASATSATPLHPSSEPLTL
>CP032698.1|AYG81477.1|4041530_4041887_+|hypothetical-protein
MSPRLHPPLEGQPAATGPHAAEPAPARPVVGAPKGVARRASASSVRFSRHNYDDGRRPVAWLHICAPRGAVPTATSKCLCGRDRSAVGYRRVLALIDDHTAHLDRCPLCASREGRNAA
>CP032698.1|AYG81476.1|4040616_4041534_+|hypothetical-protein
MTQHDPDVKRALLDAALRATESGWHVFPLRPGTKRPALHGEASCPGTGPCAGGHRKWEQRATTDVGRIRATWERAPFNVGIATGPSGLVVVDLDVPKQNDNSSADTPCGATAFKALCERTGHAVPATCRVRTASGGQHLYFTAPVGVRLTNTAGSLAPLVDTRAWGGYVVGPDSITPIGPYEAVGDAPVAPLPAWLVRLLQPAPARPAEPLRLPVVSGSRAARAALAAECAVVTASPDKQRNITLNRCAFKVGRFVAWGDIPRHVVEEAFQAAGEARGLTAAECRSTVQSALNSSLRKARSRDAA
>CP032698.1|AYG81475.1|4040075_4040531_+|hypothetical-protein
MFPEHPRHAPVERGVEVHHPTPIQPVAAPLVPVQPGTVPAVASIVLPDGRVVTGYAIEPAKPDRVAAKPAVSRTAVNVALGGIGFAAVCGGLLLLTTFIAALAALIQQLIILAAVIFGGVIAVQVLGPRHGEGGTVVNIRKAIFKRNHFRS
>CP032698.1|AYG81474.1|4037753_4039871_+|hypothetical-protein
MSTNVVRLTKDVTSAPVEPSGTPSVAVAAPGTETPPVPLWVRSGRAVRGIVTHEHTRTAARLTVRHSMYVFGGSRIVARRTWEGRTATRYERMLRAAEAAGNYEVAAEWEERGQRFREARHRRRMDLLTAPVDAAKSVLVGTSMGIGSLVALGVVLAIANKNPADVVTPLMAVVEFVQLLVTIVTIVWGPAITIGPFLALLALWAVGRHQQAAPNWALPAAVRNGEGDPITPSIVVKALRDLGVPALGRAIKEMGDAGASMLGPIRIAGCGVEVDVTLPSGVSTNEVQNRRRKLAENLSRHEHEVFITIPQAARTVRLWVADSGALDEPIGPSPLVTDETMTADYAKGRAPWGQDLRGDAAAISLYQRHLLITGLSNQGKTVALRSLALWVALDRSVQFLMGDLKGVGDWAMFEGLAKVLIQGPTDDHVIQVTEMVESAVDEMNRRLQAPPGTVFPALIVLVDEAQVAFMCPVKDDEKRPYGGSKANSRYFMAVRKIHNQGRAVNVLMWQGTQDPTDQNLPKLVREGAHTRASLALGTESQARMALGDKAVDGGAAPNLLRPGLDRGTLVVASDGIAIPAGQASITVRTHYIDDDAAVAITDRAKALRDGVTTVTVIERGEERDPLADIASVVGTADRVRTKDVLARLATLNAGAYGKWSFLDLKRVLDGTGAEPYKSDGVMVVGRDRVARALANRDADGSASAA
>CP032698.1|AYG81473.1|4037143_4037695_+|hypothetical-protein
MKLTVTTHKVSGYRQTQRTAQYLADQAGRLVARSVSGRMPDVQIVLTTARGLAELATAAEAELAGGVDKRALSREMRHAVREARDVAGRAVPLVDGSVLVLVNVDQHRTPDDFAVTLVHELVHAMQFSRKGVSGRIIRDRRHCFGVERQTRRQAREHERLMREEENEAYGREFLARQLIAAAA
>CP032698.1|AYG81483.1|4047454_4047946_-|hypothetical-protein
MADVRQVIEAALKDAELSWESPEPGAYVVTLPGTRKLSTTCSLRVGRHSLSVNAFVVRHPDENEPAVHRWLLERNLRLYGVSYAVDRLGDVYLAGRLPLSSVTAEEVDRLLGVVLEEADGSFNTLLEMGFAEAIRREYAWRVSRGESTVNLAAFERVTGGGGG
>CP032698.1|AYG81484.1|4048059_4049403_-|D-inositol-3-phosphate-glycosyltransferase
MSQYVSRFAGTLAGPPRLRLPGGHRKPRRVAMLSVHTSPLHQPGTGDAGGMNVYIVELAKRLAAINIEVEIFTRATTGGLAPTVEMSPGVLVRHVDAGPYEGLAKEELPAQLCAFTHGVMQAWAHQRPGYYDLVHSHYWLSGHVGWLAAQRWGVPLVHAMHTMAKVKNAALAEGDTPEPAARVIGETQIVNAADRLIANTAEEADELVRFYDADPGNVAVVHPGVNLDRFRPADGRTAARDRLGLPQDAFIPLFAGRIQPLKAPDVLLRAAAELLDRDPSLRSRMIVPVVGGPSGSGLAKPEGLQKLAAKLGISDVVRFRPPVGQDRLADWFRAASVLVMPSYSESFGLVAVEAQAAGTPVVAASVGGLPVAVRDGSTGFLVQGHDPKDYATALHRFVADPALVRRMGDAAARHAQSFGWGTAASATADVYTAAMYEHRRRVRSHHG
>CP032698.1|AYG81485.1|4049661_4050573_+|hypothetical-protein
MSPAPGPGLPLATTPPAVSPAPGPGRPAAYPRPMAPPAPPAKRAPAGRPVGTVTRGTTNPNRLRRMDRWIADAHGPALRRAEAPVAVDLGYGASPWTAVELLQRLRTAAPAVSVVGIEIEPARVAAAKPYEREGLTFRHGGFEVPLAEPPLLIRAANVLRQYDEDEVAAVWARLCARLAPGGLLVEGTCDEIGRRHVWVALDSEGPRTVTFATRLGSLERPSDLAERLPKALIHRNVPGEPVHSFLRDFDRAWAAAAPYASLGARQRWIRSVRELSADWPVVDGVRRWRQGEVTVNWSALAPC
>CP032698.1|AYG81486.1|4050958_4052017_+|putative-endopeptidase
MPKTRRLAIAIALVCALTAVAAPGTAFADPAPTPSTTAPAQPRTLDEVSKQIDDLYRQAAAATDAYNLAEEQTKEQSAMIVRLAQDIVKGQEKIKRLKDQAGATARMQYRNGGLPPGAQMMLSGDPDSFLTGADALRQGQQAAQGLLGELDRTQAELAAYSKDATAQWQNLEANRAKKEAAKKDITEKIAAAEKLQSQLKEEERERLAELERKKEFDSQTAWLSTGVLKEVNGSASEQGKKAVKFATDQIGKKYVWGAAGPDTFDCSGLTSQAWLAAGHPVPRTSQEQWAQLPHVAIKDMRPGDLVIYFADATHVGMYIGDGAIVHAPRPGRNVTITGAGSMPILGVVRPDK
>CP032698.1|AYG81487.1|4052322_4053588_+|hypothetical-protein
MPASQHAPVPHQRAAPEARTGSAQTGSAVDGPLNLLVIEDDPAGTFTVHELLDEAGTRVRIRTARNLTEAERLLTDDIHCILLDLALPGRDPDDELAALRHLLRLAPRHAVLALTPSTHAERAAEAVRVGAQDYLFRDELDGRLLSRAIRYAVERKRADTAQYKLAESRLRAQENARLERGLLPTPLLEGSDLRFAARYRPGRSRALLGGDFYDTVRTPDGTVHAMIGDVCGHGPDEAALGVELRIAWRALTLAGLCGDELLSTLQQVLEHERDSEEIFATLCTVDIAPDGRRAGLCLAGHPSPLIALNGRAQLLPYENSGPALGLLPRARWPRRQVELGREWGLLMYTDGLIEGRTGEGSQRLGQDGMLDMINGQLASGLRGEALLEAAVTRARELNGGELTDDVAVVLLERKRPESRAA
>CP032698.1|AYG81488.1|4053668_4054013_-|hypothetical-protein
MLLTGFSLFTSLLNLAMLVIAVVAFVFAVIAREDAYRAADKKTKPFWLIILGITVVVNLVVPVLFLQLAGLVASIVFMVDVRPALRQVSGGGRGGRRGGGSSSDGPYGPYNGGR
>CP032698.1|AYG81489.1|4054149_4054767_-|hypothetical-protein
MAITDDLRKTLTDPTPLYFLAGTADLAGQQAKKVPALIEKIQAEAPERIEAVRRTDPKVVQEKAAARVKEVQAAVTTRANDLLGAIDGDFKKLGENAQDLALRGVGVLAEYAVKAREGYDSVAEHGQEVVRQWRGEAADEIVEIAGAVEGGAPAKEAPAKDVPAQAEPVEPVEPVVGADAADQPVAKKAAPRKAPAKKPIVKSAE
>CP032698.1|AYG81490.1|4054789_4055197_-|putative-HTH-type-transcriptional-regulator
MASLNVGNLGEYLREQRRTAQLSLRQLADAAGVSNPYLSQIERGLRKPSADILQQLAKALRISAETLYVQAGILDERSPEAAGTRSVILADPSLSERQKQVLLQIYESFRKENGLDTDTDSAADGSDADHPQASN
>CP032698.1|AYG81491.1|4055287_4055674_-|hypothetical-protein
MHEITRKLASGAAVAAAALSCLVVTGPPVAASGKWCNNAVCIETYDNGDYLGRVEVSVINTNQPHRIHARVWTTNGWSAHTKVEDVSKFRTYRDQAYPQRHFPPGTRLCAEGFRGGESVGLPCVTITA
>CP032698.1|AYG81492.1|4055837_4056809_+|2-haloacrylate-reductase
MRVAQVQGFGGPEMLVHVEVADPVAGPGEVVVAVDHIDTLFVQTQIRAGGFSEFFGVEPPYVPAGGVSGTVTAIGPGVDEALAGRRVAVSGIDNTYAELVTAPAAQLCPVPDGVGLREAASLVHDAVTALALLENTALKPGETVLITGASGGMGTLLVQLAHGLGARVVGVARGPEKTALVRELGADLVIDAGDPEWGLRARAALGEGGADLILDGVGGQLGRDAFALTADGGRFSAHGAPSGTGFAAVDPDEARRRDITLLGIGDVQVTDERRTAFLARALHEVAAGRLRPVIGEVFPLARAADAHRAIEGRGLVGKVLLTP

Crispr_ID: CP032698_37

• CRISPR_ID: CP032698_37
• CRISPR_location: 4052046-4052142
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_37

Consensus_repeat	Method
GGGCACCCCCGCACCGCCGGTACGGGCAC	CRISPRCasFinder

spacers of CP032698_37

>37.1|4052075|39|CP032698|CRISPRCasFinder
CCCGCGCCGGCGGTACGGGCACCCCCGGACGGGCGCCAC

CRISPR arrays and Neighbor proteins around CP032698_37

CRISPR arrays

The CRISPR arrays of CP032698_37

>merge|CP032698|37|4052046-4052142|CRISPRCasFinder
GGGCACCCCCGCACCGCCGGTACGGGCACCCCGCGCCGGCGGTACGGGCACCCCCGGACGGGCGCCACGGGCACCCCCGGACCGCCGGTACGGGCAC

>CP032698|37|28|4052046-4052142|CRISPRCasFinder
GGGCACCCCCGCACCGCCGGTACGGGCAC	CCCGCGCCGGCGGTACGGGCACCCCCGGACGGGCGCCAC
GGGCACCCCCGGACCGCCGGTACGGGCAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81496.1|4059972_4060599_+|D-aminoacyl-tRNA-deacylase	unknown	unknown	gnl|CDD|235383
CP032698.1|AYG81491.1|4055287_4055674_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81481.1|4044851_4045613_-|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl|CDD|184519
CP032698.1|AYG81489.1|4054149_4054767_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81493.1|4056896_4058165_-|N-acetyltransferase-Eis	unknown	unknown	gnl|CDD|234945
CP032698.1|AYG81494.1|4058181_4059147_-|hypothetical-protein	unknown	unknown	gnl|CDD|377601
CP032698.1|AYG81478.1|4041883_4043047_+|hypothetical-protein	unknown	unknown	gnl|CDD|372031
CP032698.1|AYG81485.1|4049661_4050573_+|hypothetical-protein	unknown	unknown	gnl|CDD|237057
CP032698.1|AYG81484.1|4048059_4049403_-|D-inositol-3-phosphate-glycosyltransferase	unknown	unknown	gnl|CDD|132490
CP032698.1|AYG81486.1|4050958_4052017_+|putative-endopeptidase	unknown	unknown	gnl|CDD|223862
CP032698.1|AYG81482.1|4045812_4047093_+|Multidrug-resistance-protein-MdtH	unknown	unknown	gnl|CDD|340887
CP032698.1|AYG81490.1|4054789_4055197_-|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG81483.1|4047454_4047946_-|hypothetical-protein	unknown	unknown	gnl|CDD|371210
CP032698.1|AYG81492.1|4055837_4056809_+|2-haloacrylate-reductase	unknown	unknown	gnl|CDD|176206
CP032698.1|AYG81477.1|4041530_4041887_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81479.1|4043227_4043461_+|hypothetical-protein	unknown	unknown	gnl|CDD|378935
CP032698.1|AYG81495.1|4059204_4059804_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81488.1|4053668_4054013_-|hypothetical-protein	unknown	unknown	gnl|CDD|378483
CP032698.1|AYG81480.1|4043498_4044797_+|Putative-defective-protein-IntQ	unknown	unknown	gnl|CDD|271189
CP032698.1|AYG81487.1|4052322_4053588_+|hypothetical-protein	unknown	unknown	gnl|CDD|369272

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81496.1|4059972_4060599_+|D-aminoacyl-tRNA-deacylase	gnl|CDD|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	1.48949e-53
CP032698.1|AYG81493.1|4056896_4058165_-|N-acetyltransferase-Eis	gnl|CDD|234945	PRK01346, PRK01346, enhanced intracellular survival protein Eis.	1.23974e-148
CP032698.1|AYG81481.1|4044851_4045613_-|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	gnl|CDD|184519	PRK14120, gpmA, phosphoglyceromutase; Provisional.	0
CP032698.1|AYG81494.1|4058181_4059147_-|hypothetical-protein	gnl|CDD|377601	pfam06089, Asparaginase_II, L-asparaginase II. This family consists of several bacterial L-asparaginase II proteins. L-asparaginase (EC:3.5.1.1) catalyzes the hydrolysis of L-asparagine to L-aspartate and ammonium. Rhizobium etli possesses two asparaginases: asparaginase I, which is thermostable and constitutive, and asparaginase II, which is thermolabile, induced by asparagine and repressed by the carbon source.	2.7166e-138
CP032698.1|AYG81478.1|4041883_4043047_+|hypothetical-protein	gnl|CDD|372031	pfam12307, DUF3631, Protein of unknown function (DUF3631). This protein is found in bacteria. Proteins in this family are typically between 180 to 701 amino acids in length.	6.49838e-82
CP032698.1|AYG81485.1|4049661_4050573_+|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.00638886
CP032698.1|AYG81484.1|4048059_4049403_-|D-inositol-3-phosphate-glycosyltransferase	gnl|CDD|132490	TIGR03449, mycothiol_MshA, D-inositol-3-phosphate glycosyltransferase. Members of this protein family, found exclusively in the Actinobacteria, are MshA, the glycosyltransferase of mycothiol biosynthesis. Mycothiol replaces glutathione in these species.	0
CP032698.1|AYG81486.1|4050958_4052017_+|putative-endopeptidase	gnl|CDD|223862	COG0791, Spr, Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane].	8.2857e-22
CP032698.1|AYG81482.1|4045812_4047093_+|Multidrug-resistance-protein-MdtH	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.38842e-88
CP032698.1|AYG81490.1|4054789_4055197_-|putative-HTH-type-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.36082e-14
CP032698.1|AYG81483.1|4047454_4047946_-|hypothetical-protein	gnl|CDD|371210	pfam10722, YbjN, Putative bacterial sensory transduction regulator. YbjN is a putative sensory transduction regulator protein found in Proteobacteria. As it is a multi-copy suppressor of the coenzyme A-associated temperature sensitivity in temperature-sensitive mutant strains of Escherichia coli the suggestion is that it both helps CoA-A1 and possibly works as a general stabilizer for some other unstable proteins. This family was expanded to subsume other related families: DUF1790, DUF1821 and DUF2596.	3.78727e-18
CP032698.1|AYG81492.1|4055837_4056809_+|2-haloacrylate-reductase	gnl|CDD|176206	cd08244, MDR_enoyl_red, Possible enoyl reductase. Member identified as possible enoyl reductase of the MDR family. 2-enoyl thioester reductase (ETR) catalyzes the NADPH-dependent dependent conversion of trans-2-enoyl acyl carrier protein/coenzyme A (ACP/CoA) to acyl-(ACP/CoA) in fatty acid synthesis. 2-enoyl thioester reductase activity has been linked in Candida tropicalis as essential in maintaining mitiochondrial respiratory function. This ETR family is a part of the medium chain dehydrogenase/reductase family, but lack the zinc coordination sites characteristic of the alcohol dehydrogenases in this family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site, and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. Candida tropicalis enoyl thioester reductase (Etr1p) catalyzes the NADPH-dependent reduction of trans-2-enoyl thioesters in mitochondrial fatty acid synthesis. Etr1p forms homodimers, with each subunit containing a nucleotide-binding Rossmann fold domain and a catalytic domain.	2.4226e-103
CP032698.1|AYG81479.1|4043227_4043461_+|hypothetical-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	3.10713e-10
CP032698.1|AYG81488.1|4053668_4054013_-|hypothetical-protein	gnl|CDD|378483	pfam10724, DUF2516, Protein of unknown function (DUF2516). This family is conserved in Actinobacteria. The function is not known.	1.01184e-25
CP032698.1|AYG81480.1|4043498_4044797_+|Putative-defective-protein-IntQ	gnl|CDD|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	8.05206e-29
CP032698.1|AYG81487.1|4052322_4053588_+|hypothetical-protein	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	2.27607e-37

Protein sequences

>CP032698.1|AYG81486.1|4050958_4052017_+|putative-endopeptidase
MPKTRRLAIAIALVCALTAVAAPGTAFADPAPTPSTTAPAQPRTLDEVSKQIDDLYRQAAAATDAYNLAEEQTKEQSAMIVRLAQDIVKGQEKIKRLKDQAGATARMQYRNGGLPPGAQMMLSGDPDSFLTGADALRQGQQAAQGLLGELDRTQAELAAYSKDATAQWQNLEANRAKKEAAKKDITEKIAAAEKLQSQLKEEERERLAELERKKEFDSQTAWLSTGVLKEVNGSASEQGKKAVKFATDQIGKKYVWGAAGPDTFDCSGLTSQAWLAAGHPVPRTSQEQWAQLPHVAIKDMRPGDLVIYFADATHVGMYIGDGAIVHAPRPGRNVTITGAGSMPILGVVRPDK
>CP032698.1|AYG81485.1|4049661_4050573_+|hypothetical-protein
MSPAPGPGLPLATTPPAVSPAPGPGRPAAYPRPMAPPAPPAKRAPAGRPVGTVTRGTTNPNRLRRMDRWIADAHGPALRRAEAPVAVDLGYGASPWTAVELLQRLRTAAPAVSVVGIEIEPARVAAAKPYEREGLTFRHGGFEVPLAEPPLLIRAANVLRQYDEDEVAAVWARLCARLAPGGLLVEGTCDEIGRRHVWVALDSEGPRTVTFATRLGSLERPSDLAERLPKALIHRNVPGEPVHSFLRDFDRAWAAAAPYASLGARQRWIRSVRELSADWPVVDGVRRWRQGEVTVNWSALAPC
>CP032698.1|AYG81484.1|4048059_4049403_-|D-inositol-3-phosphate-glycosyltransferase
MSQYVSRFAGTLAGPPRLRLPGGHRKPRRVAMLSVHTSPLHQPGTGDAGGMNVYIVELAKRLAAINIEVEIFTRATTGGLAPTVEMSPGVLVRHVDAGPYEGLAKEELPAQLCAFTHGVMQAWAHQRPGYYDLVHSHYWLSGHVGWLAAQRWGVPLVHAMHTMAKVKNAALAEGDTPEPAARVIGETQIVNAADRLIANTAEEADELVRFYDADPGNVAVVHPGVNLDRFRPADGRTAARDRLGLPQDAFIPLFAGRIQPLKAPDVLLRAAAELLDRDPSLRSRMIVPVVGGPSGSGLAKPEGLQKLAAKLGISDVVRFRPPVGQDRLADWFRAASVLVMPSYSESFGLVAVEAQAAGTPVVAASVGGLPVAVRDGSTGFLVQGHDPKDYATALHRFVADPALVRRMGDAAARHAQSFGWGTAASATADVYTAAMYEHRRRVRSHHG
>CP032698.1|AYG81483.1|4047454_4047946_-|hypothetical-protein
MADVRQVIEAALKDAELSWESPEPGAYVVTLPGTRKLSTTCSLRVGRHSLSVNAFVVRHPDENEPAVHRWLLERNLRLYGVSYAVDRLGDVYLAGRLPLSSVTAEEVDRLLGVVLEEADGSFNTLLEMGFAEAIRREYAWRVSRGESTVNLAAFERVTGGGGG
>CP032698.1|AYG81482.1|4045812_4047093_+|Multidrug-resistance-protein-MdtH
MSIATLRRAARETVSGLPREFWWLWTSTLINRLGAFVATFMALYLTLDRGYSASYAGLVASVHGLGGVISAIAGGVMTDRLGRRPTLVIAQTSTALSVALLGFMTDPAAIVGVAFLVGMASNASRPAVQAMMADIVKPEDRVRAFSLNYWAINLGFAVSSMAAGFIAQYSYLAGFLGEATLTLICAVVVFLKLPESRPVRTAEEKVAEPSVGIGTVLRDGRFMGVVGLSFLISLIFQQGYVGLPIAMGTDGFSSADFGLAIAVNGILIVAVQLPITRYTQQRDPRQLLIVSALLAGYGFGLTAFAGSVAMYALTICVWTLAEIINAPTQTGLVVRLSPLHGRGRYQGVYTMSWSVAALLAPLLSGYVIDHFGAGWLWGTCAVLGTGTAVGYWALMRSLTATPAPANPANPADAARVRVEVRTDSGV
>CP032698.1|AYG81481.1|4044851_4045613_-|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase
MADAPYKLILLRHGESEWNEKNLFTGWVDVNLTPKGEKEAARGGELLKDAGLLPDVLHTSLQKRAIRTAQLALESADRHWIPVHRSWRLNERHYGALQGKDKAQTLAEFGEEQFMLWRRSYDTPPPALEDGTEFSQSDDARYATIPPELRPRTECLKDVVTRMLPYWYDGIVPDLLDGKTVLVAAHGNSLRALVKHLDGISDADIAGLNIPTGIPLVYELDTDFKPVNPGGTYLDPDAAAAAIEAVKNQGKKK
>CP032698.1|AYG81480.1|4043498_4044797_+|Putative-defective-protein-IntQ
MALPSPSPKGTAFMAGHIQDRWYKTETDANGKTTRVKSDRYGTGMRYRARYIAPDGTEKSKSFPDGKKRLAEEWLARIEADMSRGQYIDPKATRMTFQEFGEKWLASQSGDPNTKASMTSQLRLHAFPRIGARSLGAFQPSHIREFVTQLEGSGMSGSYARVIFSNVRAILSAAVEDGYMPRNPCTSRTVTLPEMGARRVVPWLPERVFAVRSAMVDRFRPMVDVGAGCGMRQGEILGLSVEELDFGNGTLHVVQQLKLSLSQPVFAPPKGGKLRDVPLPEPVADALREHMKLFPPVEITLPWMRAGGQPVTKRLIFTGPLGSHVWRTSLNEDHWKPALAKVGVIPKAKSREHTAAREHGMHALRHFYASVLLDAGESIKAVSEYLGHSDPGLTLKVYAHLMPSSRDRARKALGRALRPQDPPASRPTDGPE
>CP032698.1|AYG81479.1|4043227_4043461_+|hypothetical-protein
MRPPPAVADTLRNGIPDRYLTPDDIAAIFEVPKETVYQWRKKRVGPPGFRIGKHVRYDPAEVLAYVAERKGADRAAA
>CP032698.1|AYG81478.1|4041883_4043047_+|hypothetical-protein
MTTTPPAPSIDGAALLDEVEAFHRRFNIFPSEAAYVAVALWDAHAHLLDCFDSTPRLAFLSPEPGSGKSRALEIVETLVPRPMVAVNASAAALFRAVSGAEGRPTILFDEIDTVFGPKAGDNEELRGFLNAGHRRTGVTYRCVGDSQTVTPFPSYAAVAVAGLGSLPDTILTRAVIIRMRRRARNEKVEPFRARLHEQEGHALRDRLAEWAEQARGWVMGAWPEMPDGVSDRPADVWEGLLSIADAAGGDWPKRARQACLTLVEASRANDKGSLGIRLLTDLRDHVLIGIDRLPTVAILDRLNALDDAPWADLNGRPLDNRRLSKMLSDYVTADGGPIASRNIRTSGGILKGFFAEDLTDAWARYCPSPASATSATPLHPSSEPLTL
>CP032698.1|AYG81477.1|4041530_4041887_+|hypothetical-protein
MSPRLHPPLEGQPAATGPHAAEPAPARPVVGAPKGVARRASASSVRFSRHNYDDGRRPVAWLHICAPRGAVPTATSKCLCGRDRSAVGYRRVLALIDDHTAHLDRCPLCASREGRNAA
>CP032698.1|AYG81487.1|4052322_4053588_+|hypothetical-protein
MPASQHAPVPHQRAAPEARTGSAQTGSAVDGPLNLLVIEDDPAGTFTVHELLDEAGTRVRIRTARNLTEAERLLTDDIHCILLDLALPGRDPDDELAALRHLLRLAPRHAVLALTPSTHAERAAEAVRVGAQDYLFRDELDGRLLSRAIRYAVERKRADTAQYKLAESRLRAQENARLERGLLPTPLLEGSDLRFAARYRPGRSRALLGGDFYDTVRTPDGTVHAMIGDVCGHGPDEAALGVELRIAWRALTLAGLCGDELLSTLQQVLEHERDSEEIFATLCTVDIAPDGRRAGLCLAGHPSPLIALNGRAQLLPYENSGPALGLLPRARWPRRQVELGREWGLLMYTDGLIEGRTGEGSQRLGQDGMLDMINGQLASGLRGEALLEAAVTRARELNGGELTDDVAVVLLERKRPESRAA
>CP032698.1|AYG81488.1|4053668_4054013_-|hypothetical-protein
MLLTGFSLFTSLLNLAMLVIAVVAFVFAVIAREDAYRAADKKTKPFWLIILGITVVVNLVVPVLFLQLAGLVASIVFMVDVRPALRQVSGGGRGGRRGGGSSSDGPYGPYNGGR
>CP032698.1|AYG81489.1|4054149_4054767_-|hypothetical-protein
MAITDDLRKTLTDPTPLYFLAGTADLAGQQAKKVPALIEKIQAEAPERIEAVRRTDPKVVQEKAAARVKEVQAAVTTRANDLLGAIDGDFKKLGENAQDLALRGVGVLAEYAVKAREGYDSVAEHGQEVVRQWRGEAADEIVEIAGAVEGGAPAKEAPAKDVPAQAEPVEPVEPVVGADAADQPVAKKAAPRKAPAKKPIVKSAE
>CP032698.1|AYG81490.1|4054789_4055197_-|putative-HTH-type-transcriptional-regulator
MASLNVGNLGEYLREQRRTAQLSLRQLADAAGVSNPYLSQIERGLRKPSADILQQLAKALRISAETLYVQAGILDERSPEAAGTRSVILADPSLSERQKQVLLQIYESFRKENGLDTDTDSAADGSDADHPQASN
>CP032698.1|AYG81491.1|4055287_4055674_-|hypothetical-protein
MHEITRKLASGAAVAAAALSCLVVTGPPVAASGKWCNNAVCIETYDNGDYLGRVEVSVINTNQPHRIHARVWTTNGWSAHTKVEDVSKFRTYRDQAYPQRHFPPGTRLCAEGFRGGESVGLPCVTITA
>CP032698.1|AYG81492.1|4055837_4056809_+|2-haloacrylate-reductase
MRVAQVQGFGGPEMLVHVEVADPVAGPGEVVVAVDHIDTLFVQTQIRAGGFSEFFGVEPPYVPAGGVSGTVTAIGPGVDEALAGRRVAVSGIDNTYAELVTAPAAQLCPVPDGVGLREAASLVHDAVTALALLENTALKPGETVLITGASGGMGTLLVQLAHGLGARVVGVARGPEKTALVRELGADLVIDAGDPEWGLRARAALGEGGADLILDGVGGQLGRDAFALTADGGRFSAHGAPSGTGFAAVDPDEARRRDITLLGIGDVQVTDERRTAFLARALHEVAAGRLRPVIGEVFPLARAADAHRAIEGRGLVGKVLLTP
>CP032698.1|AYG81493.1|4056896_4058165_-|N-acetyltransferase-Eis
MAAMSSPGTSDIEVRTVTDDEFTHWMKAVAVGFLRSPVVGEEYARDLRANSDLSRVRGAFDDGRCVATFRSFAQELTVPGGAALPVSAVSGVTVTPTHRRRGLLTRMMAVDLAEARERGDVASTLIAAEYPIYGRYGYGPATHLAEWEIDTARTGLDPHWSRPADGGRVDLVDPAEAAKIGTEVFERFRPSRAGVISRDRRWWDLTTGVVRREGPWTEPFFAVYRTADGEPAGIAAYTADERWSDAKLPENTATVKSLIGLTPAADRALWHFLCSIDWIRTVRTGYRAPDDLLPLFFANPRAARIVTHGDFLWLRLLDVVRALEARAYAGEGALVLEVEDAAGPAAGRFLLEADETGARCTPTTRSAELTLDARELASLYLGDESASRLLALGRVAEERPGAAARADALFRTARRPWCPDMF
>CP032698.1|AYG81494.1|4058181_4059147_-|hypothetical-protein
MTAVSSTSPIPPVLAEVVRSGFVEGHHRGSLVVLAADGSVEFSLGDPAAPVFPRSSNKPMQAAAVLRAGLDLSGERLAIAAASHSGEGFHLDLVRKMLAEHGLTPDDLQTPPDLPLDAVEAETYLAAGHVRERLTMNCSGKHAAMLAACKQNGWDLATYLDPAHPLQRLVLESVESAAGERVASVGTDGCGAPLMAIGLTGLARAFRTFATAGAGSPEGRVAEAMRAHPEYVAGTRRPDTWLMREVPGTLSKMGAEAVQAVAFADGRALAFKVDDGAIRALGPVLARALRLMGVDAPVVDRIGRAPLLGGAAEVGEIRATF
>CP032698.1|AYG81495.1|4059204_4059804_-|hypothetical-protein
MTTPGAGQSPGPVSLTRTSPRTTTAVRPPVRRAGGTLPPQRDHDLAALRLAELRTLRRQSQRDEADLSYVRRLLHGRIDILRAELARRTGPQAPVVERLAEILTDAPSSHRASARHVTLSAPRSEEYRTLAAAMDAEVELSDLDARTDDELHTATGRLIRYEQHVSRRRKEVQRTADDCSAEIARRYRDGEAQVDDLLI
>CP032698.1|AYG81496.1|4059972_4060599_+|D-aminoacyl-tRNA-deacylase
MRAVVQRVDGARVVVAGETVGEITGEGLCVLVGVTHEDTPDKAAQLARKLWSVRILEGEKSCSDVNAPLLVISQFTLYGDARKGRRPTWNAAAPARWRSPWSTRWWPNSGRWAPRWRRAGSARTCGCRSPTTARSRSSSTSEPHGPAPGRMSEPHGSAPGPAQGRTTSSIRPYGSTTTSWAAAVFPASSSASTGTFRLTRASAIGPSS

Crispr_ID: CP032698_39

• CRISPR_ID: CP032698_39
• CRISPR_location: 4136098-4136194
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_39

Consensus_repeat	Method
CCCTGGGGCTCCGCCCCAGTCCCC	CRISPRCasFinder

spacers of CP032698_39

>39.1|4136122|49|CP032698|CRISPRCasFinder
AGGCACCTCGCCCACCCGCCCGCCCGTGCAGCGGGTTGGTTGGTTCCGG

CRISPR arrays and Neighbor proteins around CP032698_39

CRISPR arrays

The CRISPR arrays of CP032698_39

>merge|CP032698|39|4136098-4136194|CRISPRCasFinder
CCCTGGGGCTCCGCCCCAGTCCCCAGGCACCTCGCCCACCCGCCCGCCCGTGCAGCGGGTTGGTTGGTTCCGGCCCTGGGGCTCCGCCCCAGACCCC

>CP032698|39|30|4136098-4136194|CRISPRCasFinder
CCCTGGGGCTCCGCCCCAGTCCCC	AGGCACCTCGCCCACCCGCCCGCCCGTGCAGCGGGTTGGTTGGTTCCGG
CCCTGGGGCTCCGCCCCAGACCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81555.1|4130454_4131870_+|55.5-kDa-and-49.5-kDa-sporulation-proteins	unknown	unknown	unknown
CP032698.1|AYG81561.1|4139288_4139552_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81565.1|4145778_4146324_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
CP032698.1|AYG81563.1|4141548_4143171_-|Low-affinity-putrescine-importer-PlaP	unknown	unknown	gnl|CDD|273331
CP032698.1|AYG81564.1|4143284_4145582_-|ATP-dependent-RNA-helicase-RhlE	unknown	unknown	gnl|CDD|223587
CP032698.1|AYG81562.1|4139853_4140915_-|Anthranilate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234682
CP032698.1|AYG81554.1|4130002_4130290_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81556.1|4131979_4133182_+|L-2-hydroxyglutarate-oxidase-LhgO	unknown	unknown	gnl|CDD|183292
CP032698.1|AYG81566.1|4146528_4147158_-|hypothetical-protein	unknown	unknown	gnl|CDD|240572
CP032698.1|AYG81558.1|4134639_4136055_+|hypothetical-protein	unknown	unknown	gnl|CDD|379143
CP032698.1|AYG81550.1|4121099_4121924_+|hypothetical-protein	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG81568.1|4148859_4149624_-|Disulfide-bond-formation-protein-D	unknown	unknown	gnl|CDD|372611
CP032698.1|AYG81549.1|4119402_4120725_-|NADH-dehydrogenase-like-protein	unknown	unknown	gnl|CDD|224172
CP032698.1|AYG81552.1|4124198_4127390_-|Putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|226418
CP032698.1|AYG81557.1|4133764_4134565_+|tRNA-(guanine-N(7)-)-methyltransferase	unknown	unknown	gnl|CDD|234649
CP032698.1|AYG81553.1|4127539_4129663_-|hypothetical-protein	unknown	unknown	gnl|CDD|273676
CP032698.1|AYG81551.1|4122134_4124168_+|hypothetical-protein	unknown	unknown	gnl|CDD|214816
CP032698.1|AYG81559.1|4136543_4137650_-|Glycyl-glycine-endopeptidase-ALE-1	unknown	unknown	gnl|CDD|366703
CP032698.1|AYG81560.1|4138103_4139225_-|hypothetical-protein	unknown	unknown	gnl|CDD|369272
CP032698.1|AYG81567.1|4148029_4148863_-|hypothetical-protein	unknown	unknown	gnl|CDD|223856

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81565.1|4145778_4146324_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	9.24893e-10
CP032698.1|AYG81563.1|4141548_4143171_-|Low-affinity-putrescine-importer-PlaP	gnl|CDD|273331	TIGR00907, Choline_transport_protein, amino acid permease (GABA permease). [Transport and binding proteins, Amino acids, peptides and amines].	4.25407e-137
CP032698.1|AYG81564.1|4143284_4145582_-|ATP-dependent-RNA-helicase-RhlE	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	1.16248e-118
CP032698.1|AYG81562.1|4139853_4140915_-|Anthranilate-phosphoribosyltransferase	gnl|CDD|234682	PRK00188, trpD, anthranilate phosphoribosyltransferase; Provisional.	4.34773e-145
CP032698.1|AYG81556.1|4131979_4133182_+|L-2-hydroxyglutarate-oxidase-LhgO	gnl|CDD|183292	PRK11728, PRK11728, L-2-hydroxyglutarate oxidase.	0
CP032698.1|AYG81566.1|4146528_4147158_-|hypothetical-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	1.89813e-48
CP032698.1|AYG81558.1|4134639_4136055_+|hypothetical-protein	gnl|CDD|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	5.45357e-48
CP032698.1|AYG81550.1|4121099_4121924_+|hypothetical-protein	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.09552e-10
CP032698.1|AYG81568.1|4148859_4149624_-|Disulfide-bond-formation-protein-D	gnl|CDD|372611	pfam13462, Thioredoxin_4, Thioredoxin.	3.35274e-29
CP032698.1|AYG81549.1|4119402_4120725_-|NADH-dehydrogenase-like-protein	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	1.05697e-94
CP032698.1|AYG81552.1|4124198_4127390_-|Putative-HTH-type-transcriptional-regulator	gnl|CDD|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	9.06492e-59
CP032698.1|AYG81557.1|4133764_4134565_+|tRNA-(guanine-N(7)-)-methyltransferase	gnl|CDD|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.06811e-86
CP032698.1|AYG81553.1|4127539_4129663_-|hypothetical-protein	gnl|CDD|273676	TIGR01536, Asparagine_synthetase_1, asparagine synthase (glutamine-hydrolyzing). This model describes the glutamine-hydrolysing asparagine synthase. A poorly conserved C-terminal extension was removed from the model. Bacterial members of the family tend to have a long, poorly conserved insert lacking from archaeal and eukaryotic sequences. Multiple isozymes have been demonstrated, such as in Bacillus subtilis. Long-branch members of the phylogenetic tree (which typically were also second or third candidate members from their genomes) were removed from the seed alignment and score below trusted cutoff. [Amino acid biosynthesis, Aspartate family].	6.87475e-05
CP032698.1|AYG81551.1|4122134_4124168_+|hypothetical-protein	gnl|CDD|214816	smart00776, NPCBM, This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins.	2.64605e-37
CP032698.1|AYG81559.1|4136543_4137650_-|Glycyl-glycine-endopeptidase-ALE-1	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	8.21404e-35
CP032698.1|AYG81560.1|4138103_4139225_-|hypothetical-protein	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	3.93448e-39
CP032698.1|AYG81567.1|4148029_4148863_-|hypothetical-protein	gnl|CDD|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	5.71192e-24

Protein sequences

>CP032698.1|AYG81558.1|4134639_4136055_+|hypothetical-protein
MSFESLPHRPHPGQAPQQAGSAFSAQPVPACADEPRFDAVPPDRAKWRYRPRRDFWRSKAVRAGALITLLALCGLVIFALVRDETGTEGFLVGLGLAVLPVPLLAAAFRWLDRVDPGPWRNLFFALAWGACAAALVAIIANSFATRWIATATADPSSADHLGAGVIAPIVEESAKAAAVLLLFLFRRRDFKSLVDGVVFAGFTATGFAFTENILYLGNAFGEDQASHSGGLASTTAATFFVRVVMSPFAHPLFTVMTGIGFGVAALAPSGRRLRRVVFPLLGLVCAMGMHALWNSSTLFGAYGFLIVYGGFMVPAFGLVTWLAIWSRQRELRTVAAELPAYAAAGWLGLAEPFALSSMRARATAREFAQHRLGGKSAARAVAEYEAFATALAFLRHRAYRSAGATGPGPDFAAREQELLHHLWERKPVAGPALLYAAGATGRAWPPPHPGPPSPYPYWPPTPPPTYNPYLT
>CP032698.1|AYG81557.1|4133764_4134565_+|tRNA-(guanine-N(7)-)-methyltransferase
MSEQPQTPEPPAPRTEKVLPRDKAPRFPGGPAADPAGSHHERRIRSFQPRRSRVTTGQGEYLERLWPVWGFDIDGLREIDLVEMFEGLPVVLEIGFGMGEATAQMAADDPGTGILAVDVHTPGQGNLLGLAERGGLNNVRVANGDAIILLREMLRPDALDGLRVYFPDPWPKKRHHKRRLIQPEFLSLAATRMKPGAVLHCATDWEDYAEQMLEVLDAHPDFENTVDGGGYAPRPAFRPLTRFEGQGLDKGHVVHDLLFRRVGHGG
>CP032698.1|AYG81556.1|4131979_4133182_+|L-2-hydroxyglutarate-oxidase-LhgO
MTTYDCDVLVVGGGIVGLSTAYALTREAPGTRVTVLEKENGPARHQTGRNSGVIHSGIYYKPGSLKARFAVRGAAEMVEFCARHGIPHEVTGKLIVATERAELPRLHALVQRGRENGIPVRELGPPQIAAYEPEVRGLAAIHVGTTGVCDYGAVAARLAELSGAEVRYGAEVVHIDRRPSLGVAVRLADGTVLRARALVNCAGLHCDRVARLAGDDPGVRIVPFRGEYYELARPGLVKGLVYPVPDPAFPFLGVHLTRGVDGTVHVGPNAVPAAAREGYDWRTVRPRELAGTLAWPGSWRIARRHWRYGAGELHRSWSKRAFTDAVRRLLPSVREADLRPAPAGVRAQAVLRDGTLVDDFLIRSAPRTIHVLNAPSPAATASLPIGREVARRALAALPRP
>CP032698.1|AYG81555.1|4130454_4131870_+|55.5-kDa-and-49.5-kDa-sporulation-proteins
MSREQRGPNEKLGTVLALAGISNAGLARRVNDLGAQRGLTLRYDKTSVARWVSKGMVPQGAAPHLIAAAIGAKLGRPVPLHEIGLADADPAPEVGLAFPRDVSEAVRSATDLYRLDLAGRRAGGGIWQSLAGSFAVSAYATPASRWLITPADSSVARSVELTDLPPLKVGHSDVAKLREAAEDARRWDSKYGGGDWRSSMVPECLRVDAAPLLLGSYSDEVGRALFGATAELTRLAGWMAFDTGQQEAAQRYYIQALRLARAAADVPLGGYVLASMSLQATYRGFADEGVDLAQAAVERNRGLATARTMSFFRLVEARAHAKAGDGHPAEAALKAAEAWLERSRDGDCDPSWLGFYSYDRFAADAAECYRDLKAPRQVRRFTEQALSRPTEEFVRSHGLRLVVSAVAELESGNLDAACAAGTRAVEVAGRISSARTTEYVRDLLHRLEPYGDEPRVAELRERARPLLVTPA
>CP032698.1|AYG81554.1|4130002_4130290_-|hypothetical-protein
MARLFSVRPVADTGGRGPAAERLRRGAAGPVAAALPTCGRAPGRALSPVPQGSASMCGAWVGPLRGSSGLGDTAASIPAGGGPVREANSASRTVC
>CP032698.1|AYG81553.1|4127539_4129663_-|hypothetical-protein
MRWLVGWSSVAASFRAGAQGAGGYGTAGAVGEPDEGRTVHPVGAQLLWGDPDPLWAVGDWRPDEIRIVSVGADTRLAVLGCCAATDEELRVGLFAARGGALRHLTAWPGSYTAVAQVARRVTVVGDLAGARPVFYTPWAGGTAYGTAALPLADLIEAQLDIGHLAALLACPDVPEALGDSTPYAGVRRIPPGHALVLREGSREITGYEPVASLAVAAPQLAPVAAVDGVRDALVAAVRARLTAPRHAPETLPPDPGPVPGMGPAERRAARGGPAPGIGADLSGGPASATLALLAAGLPGVPGTVLGHGTGAGERLLAVTFNDLTVPGAGRQAELERAGAMAANPRLHHVVVTGGEEFLPYADLEGPLTDEPGPSLIAAPRHRRRLLSGSADHFTGSGARQVLDAHPARLADLLMDRQRRHLLRPATALAKAGGPSANSLFVPLTVYRAARRLARTPYRAGIESAADALREPSFDDATSPLSISLAALSWTRPGPAARWLTGEALAEVSARLMASATRPAPSQRPGQARASAALARYAADHRVLEQAAEVRSQRLHAPFLDNQVVRACRALPESLRVQPGARATILRTVLSASGVRDLPPGWGAPSHGPTATARAGLRHFADPLISLFEAPLLADAGLIEARTVRKAVRAAAAGEPLPLDGLADLISTELWLRRLLSRRGTCWTGTAAPRQRAVAGGVTPPRRPTLRS
>CP032698.1|AYG81552.1|4124198_4127390_-|Putative-HTH-type-transcriptional-regulator
MRYLILGATEAHEPDGTSIPLGGRRVRALLTALALRVPRAVPVATLIDDVWADDPPQDAPAALQALVGRLRRALGKDAVESGPAGYRLTAPRHAVDLFVFEERAAQGAAQLAAGEPERAATTLRAALALWRGPALCDLPEPDGAVRAEAQRLSARRNRIEADLRRGATHGLLPELTELLASYPYDETLHSQMIRTLVAEGRRADALAAYEQARRTLADALGTDPGPELAALHAELLAGGPAVERPAPAPSPRPEGNLRPRLTSFVGREPELASIQGDLATYRLVTLTGPGGTGKTRLAEQAASAARVDAWLVELAPLDDPGAVPGAVVSALGLRETTLLAREGQPGHDDPTARLADDLSRRPDTLLVLDNCEHVIDAAARLAETLLTRCPRLRILATSREPLGVPGETVRPVEPLPPAPAHRLFAERARAVRPDFDPGADPEAVAEICRRLDGLPLAIELAAARLRLLTPRQIADRLDDRFRLLTGGSRTVLPRQQTLRAVVDWSWDLLEEPERTVLRRASVFAGGWDLAAAQAVCAATDDLAALVEKSLVIAVPAPDGSGMRYRMLETIHEYATERAAETPQVLREAADAHTAYYRALVAEAEPLIRSAEQLPWIRCLETELDNIRAALRRTTTGRTADEEAATELVLNMGWFWWLRNYRTEGAGWGRAAAELAPLPDDECDPRYWPRLHLDLLRYFLLSDVERGHGLEDNGVQDRLAELRKAFEGGGPQAARFPGLLWPFATFHTDPPGLVRDSINGVVANCRRYGDDWATAVSLMFRTHMSIDMPGGLEGVDEDLAELRELGRRVGDRWMRAQVAGAAAEAAMTRGLSEVARPAYEEALQLAREVGAHQETPFLTARVGELAYRQGDLDAAEKSLTEAAADALRYRVAEALPYVHSLLATIALDRGDTVTALALRDQALDFAEKGPPGAPPHFVALLDALDARTTAIESGPLAGLRGMANALRTAAGGRCTEHVLAHLAERAAQFLGDLGEHGRALRLLAAASTWRADIPRSVPERAIEESIRLRAREALTPERYEAEYAAGSPLTPTEIPPILDEVTEA
>CP032698.1|AYG81551.1|4122134_4124168_+|hypothetical-protein
MGVEERDESLSGGGGPESGGPDGGRPPRQVPSQGGFGPGAPSGPAPVPGQAAKGSGYEHAGDFGLAGGAGLGGTVLPGPWGPMDGIGDPGSSVPTQREGGLRDGVTLDLPEVGQSDADLIHAMRAGDDSAYEELFRRHSEAVRRYARTCCRDAHTADDLTAEVFARTLQAVRGGAGPEHAVRAYLMTTVRRVAATWTRTAKREHLVDDFAVFAQQSARSTEAFDDDTIDLGAEVRAMHEAEQTLAMQAFRSLPERWQAVLWHTTVEEESPSEIAPLFGLTANATAVLASRAREGLKQAYLQAHVSTALTSGGDCARYADRLGAYARGGLRMRAERGLSKHLEECAKCRVAVIELKDVNAGIPALLPVAVIGWFAAGFSLKAAGVVAGGAAGAAGAGAAAAATGSGASSGAAGGAAVSEGLGAPAKAGIAAAVAVAVAAGIVFALTGNDAPAPKPDAKPPAVVPAVPHKPPPAPEPPAAPAAAPTPPPRPAPKKPAARPLPPTPTRPAPTPPRPTPPKPTPPKPTPAKPPPPPAPSVFQVNRLEYGLLGDGTKPEVRLGGSSWLWQRSGMSIDGHRYPHGVTVHGRSSVTIDLNRQCRTYDAYAGVDDLMAGLGAVRFSLYGDATRLWQSPVVHAGDPAVPVHADIAGRRTIRLVVEPAGPFGGAALADWAQSRIGCA
>CP032698.1|AYG81550.1|4121099_4121924_+|hypothetical-protein
MHIQDSHWQTAVASSDGHGRVGTAPGAGGSRSAPLRVDAQRNLEHVLRAAREVFGELGYGAPMEDVARRARVGVGTVYRRFPSKDVLVRRIAEEETSRLTDQARTALGQENEPWSALSRFLRTSVASGAGRLLPPQVLRVGVDAEETEGVRPEAPRDETSRPDGVRDGFDEARVPQQRQVGSAEQGAAWGRVIAQRTAPEQELDDPGAAELLDVVGQLVDRARAAGELRVDVTVADVLLVIATAAPSLPDANQQAAASSRLLDILLEGLRSRPS
>CP032698.1|AYG81549.1|4119402_4120725_-|NADH-dehydrogenase-like-protein
MYTALRLQRKLKTELRAGTAEITVVAPDPYMTYQPFLPEAAAGNISPRHVVVPLRRVLDKCRIVIGEADRIDHAHRTATVTTLASPEDGTGAIRLTYDELVIAPGSISRTLPVPGLADYAIGFKTVEEAIGLRNHVIEQMDIASSTRDPAVRDAALTFVVVGGGYAGVEALAELEDMARYTARYYHNIRPEDLKWILVEASDRILPEVGEEMGRYAIRELRSRNIDVRLETRLDSCENRIAVLSDGARFPTRTVVWTAGVKPAPLLAATDLPLNERGRIECTAQLRVAGTDHAWAGGDAAAVPDLTSREKGKECAPNAQHAVRQAKVLAENVAAAVRGGEPVEYRHSYAGSVASLGLHKGVAHVYGRKLKGYPAWFMHRAYHLSRVPTFNRKARVLAEWTLAGLFKREIVSLGSLEHPRAEFEIAAGGGPPGKGPAPQDT
>CP032698.1|AYG81559.1|4136543_4137650_-|Glycyl-glycine-endopeptidase-ALE-1
MAANEPALGTPLPAFPSTTLDPARPQPLYGDAPGETETWEEWDPTEESVRPVRGRHRVAKQRGGGLARSSTVLGVGVIAAVGAGGMASAQSKPPVSISLPDSLSASLPDLGSLPGVGELVPHHAPDSLTSGAAQADQKIAAAPLTMTGLSTGEAERGATDAGEALRARILQQAAQQKAGAAAEAKAAAQQAAAQKAAREAAAQQDAARAKAAAEKKAQEEAAEKKAEEERLAKLAASYSLPVGSNTLTSTFGEAGSMWSSGHHTGLDFAAPTGTPLKAIHSGTIVSAGWAGAYGYRTVVKLDDGSELWYCHQSSIAVSAGQRVATGEVVGRVGATGNVTGPHLHLEVHTPSGTGIDPMTWLQSKGLAP
>CP032698.1|AYG81560.1|4138103_4139225_-|hypothetical-protein
MRQRAEGDRRLVRALPVLLIVVGFVFDASTPPDLTAAALFAGAPVAAAPFYSDRGTAAVGAGSVAAVVALWFIHDLPNLGEGASELFTVLTVSALALVINRILRHSGEQLASARVIAETAQRAVLPTPAARIGGLHVAARYEAAQADAFIGGDLFAVQDTPYGVRLIVGDVRGKGLQAVEAVAVVIGAFREAAEQESSLEAVTQRLERALAREGTRRDRLDAVEGFTTALLAEIPRGESTVRLVNRGHPEPFLLHADGSLDALVPSEPALPLGMSDLGVWPDRADARPFPAGSMLLLYTDGLSEARDKAGVFYQPGARLSGAIFPGPEEVLDALVDDVRRYTGGGSSDDMALLAVARPAEGQPERRRTVQIVK
>CP032698.1|AYG81561.1|4139288_4139552_-|hypothetical-protein
MRRRVLAGVLLVVGLGAGLSGCQEAGGPVPVVVRGPAVGVTVPAHGCRLNRDGWAELPCVPERAANHRHTRGSCVRGRPGPHRCRRH
>CP032698.1|AYG81562.1|4139853_4140915_-|Anthranilate-phosphoribosyltransferase
MIEAGRTWRHLLAVLLRGEDLGADDARWAMRQVMDDAADPAQLAGFLVALRAKGESAEEIHGLLDALMERVVPLPVDGADVVDIVGTGGDGAHTVNVSTMAAVVVAGAGVPVVKHGGRSVSSKAGAADVLEALGLPLDLTPDAVARCVRETGIGFTFAPRFHHGLRHAGPVRKSLGVPTVINYLAPLTNPARPRTAVVGCSNTALAPVLADVLAARGASALVVRGDDGLDEITTAAPTRAWVAAAGRVRQVGLDTAEFGLPRCAPDALRGGDAAYNARAVHRVMDGETGPVRDAVLANAAGALAAYRGFGDRDLPDAFAAALDEARHALDSGAAARTLKTWLDLARSLRGPAR
>CP032698.1|AYG81563.1|4141548_4143171_-|Low-affinity-putrescine-importer-PlaP
MSRGPRIRRSVRFRPRHGAWSAPGEGIAGGMTNDASTNSPEKQGSAGAEGSAGVATTDEERLAQLGYKQVLARRMSAFSNYAVSFTIISVLSGCLTMYAYGMKTGGPALITWGWVAVGLMTLVVGLAMAEICSAYPTSAGLYFWAHRLAPPRSAAAWAWFTGWFNVLGQIAVTAGVDFGAASFLGAYLNLQFGFEVTPARTILLFAAILLLHGLLNTFGVRIVALLNSVSVWWHVLGVVAIVAALLFVPDTHQSTSFVFTRFVNETGFTNGVYVVLIGLLMAQYTFTGYDASAHMTEETHDASTAGPRGIVRSIWTSWIAGFVLLLGFTYAIGSYDTQLDSATGAPPAQILLDSLGETGGKLLLLVVIGAQLFCGMASVTANSRMIYAFSRDGALPFSRLWHTVSPRTRTPVAAVWLAAGAALVLGLPYLINVTAYAAVTSIAVIGLYIAYVIPTLLRLFRGDAFTPGPWHLGRWSRPVGIVAVAWVTVITVLFMLPQVSPVTWETFNYAPLAVLAVLGFATAWWLASARHWFLRGVRGE
>CP032698.1|AYG81564.1|4143284_4145582_-|ATP-dependent-RNA-helicase-RhlE
MSISSTDHSVLPENENNDSIEAVQVVEARENDVVEAVAASDVIEVVEIVESEADENDENAEPTVTFAALGLPEGVVRKLAQNGVTSPFPIQAATIPDALAGKDILGRGRTGSGKTLSFGLPTLAQLAGGHTEKKKPRAIILTPTRELAMQVADALQPYGDVLGLKMKVVCGGTSMSNQIYALERGVDVLVATPGRLRDLINRGACSLANVQVAVLDEADQMSDLGFLPEVTELLDQIPGGGQRMLFSATMENEISTLVKRYLTNPVTHEVDSAQGNVSTMTHHVLVVKPKDKAPVTAAIAARKGRTIIFVRTQLGADRIAEQLCESGVKADALHGGMTQGARTRVLEDFKKGYVNALVATDVAARGIHVDGIDLVLNVDPAGDHKDYLHRSGRTARAGKSGVVVSLSLPHQRRQIFRLMEDAGVDASRHIIQSAGAFDPEVAEITGARSLTEVQADSANNSAKQAEREVADLTKQLERLTRRAGELREEADRLVARAARERGEDPEAAVAEVAAEAEAEVAAAAAAAAVPVQQESREERGGFQRRDDRGNFERRDNRGGDRGERGGFNRDRRDERPSGGFNRGGGDRPFNRDRRDERPAGGGFRRDDRPSGGFRRDDRPSGGSNRDDRGGDRGGFRRDDRPSGGFRRDERPSGGFNRDDRGGDRGGFRRDDRPSGGFNRDDRGGERGGFNRDRRDERPSGGFNRGGGDRPFNRDRRDERPAGGGFRTGGHDRPQGRRDDHRGTGTGTATGSFGRRDDKPRWKRNG
>CP032698.1|AYG81565.1|4145778_4146324_-|hypothetical-protein
MRQLTTPVRLAELAVTVLVLTASAGCMSVSEDEGKPKPSVSAGQHGGAAASDEGKGGSGAGREHGGKRDPKAPGGSAGKPSAGGSPGASGPAAPSAGANPKPGGPGPAKPSPGAPSKPAPSPTRSVPAPPPVSPPAPPSSSPPPAASPSTTPGADTHNTALHRNQPPIDPEPTASPQVGPV
>CP032698.1|AYG81566.1|4146528_4147158_-|hypothetical-protein
MARLGALQRVGDVRSIWDAGRYRQNGFRGGPAAPTGDRHRTDDERHRGDPDGAARTGPDQDGPDQGEPHPHSPEPHPPEPHSAPTPQVTHNGRVLEMTREEFEELVGEALDRIPPELTRLMDNVAVFVEDEPAPDDPELLGLYEGTPLTDRGEWYAGVLPDRITIYRGPTLRMCETREEVVAETEVTVVHEIAHHFGIDDERLHALGYG
>CP032698.1|AYG81567.1|4148029_4148863_-|hypothetical-protein
MTPNIGYFAAFLGGLLALLSPCSALLLPAFFAYSISSRTKLLARTGIFYAGLATTLVPLGAAGSYAGRLFYGHRDALVLFGGWLIIVLGVAQIVGMGFASRRMTELSGRIRPTTALSVYALGAVYGLAGFCAGPILGSVLTVAAVSGSPLYGGLLLAVYALGMAVPLFLLALLWERFELGGRTWLRGRVVRVARFELHTTSLLSGLFFIALGALFLAYDGATGLPGVLDVDESYAVEEWARGVGGWVPDWALLLVVVGVVGLLLTTRARRPKPPPRS
>CP032698.1|AYG81568.1|4148859_4149624_-|Disulfide-bond-formation-protein-D
MSRPKTQSKQTARKPAKSRKQPYLIGAAVLVVAGVLGMASYQVSAPDPRPAVDGSGAAAASDPAPADAHPELTGLARRDAKDPLAQGRADAPVVMIEYADFKCSYCGKFARDTEPELVKKYVDDGTLRIEWRNFPIFGAESEAAARGAWAAGQQGRFWQFHAAAYARDAKEKGFGGDRLKELAKEAGVPDAARFAADLDGEAAKAAVKKDQDEAYALGASSTPSFLINGTPLAGAQPMDSFAQVIDAAARTAKK

Crispr_ID: CP032698_38

• CRISPR_ID: CP032698_38
• CRISPR_location: 4133490-4133635
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_38

Consensus_repeat	Method
CTTTAGGGGCGCGGGGAACTGCGCGACCAG	PILER-CR
GGGGCGCGGGGAACTGCGCGACCAG	CRISPRCasFinder

spacers of CP032698_38

>38.1|4133520|30|CP032698|PILER-CR
GACGCGGGCACGGTCCGCAGGATCGAGAGG
>38.2|4133580|30|CP032698|PILER-CR
CCACCTGCGGGCCGCAGACGAAAACAGGTT
>38.3|4133520|31|CP032698|CRISPRCasFinder
CGGGCACGGTCCGCAGGATCGAGAGGGGTTA
>38.4|4133576|35|CP032698|CRISPRCasFinder
CCACCTGCGGGCCGCAGACGAAAACAGGTTCTTTG

CRISPR arrays and Neighbor proteins around CP032698_38

CRISPR arrays

The CRISPR arrays of CP032698_38

>merge|CP032698|38|4133490-4133635|PILER-CR,CRISPRCasFinder
CTTAAGGGGCGCGAGGAACTGCGCGAGACGCGGGCACGGTCCGCAGGATCGAGAGGGGTTAGGGGCGCGGGGAACTGCGCGACCAGCCACCTGCGGGCCGCAGACGAAAACAGGTTCTTTGGGGGCGCGGGGAACTGCGCGATCAG

>CP032698|38|11|4133490-4133635|PILER-CR
CTTAAGGGGCGCGAGGAACTGCGCGAGACG	CGGGCACGGTCCGCAGGATCGAGAGGGGTT
AGGGGCGCGGGGAACTGCGCGACCAGCCAC	CTGCGGGCCGCAGACGAAAACAGGTTCTTT
GGGGGCGCGGGGAACTGCGCGATCAG

>CP032698|38|29|4133495-4133635|CRISPRCasFinder
GGGGCGCGAGGAACTGCGCGAGACG	CGGGCACGGTCCGCAGGATCGAGAGGGGTTA
GGGGCGCGGGGAACTGCGCGACCAG	CCACCTGCGGGCCGCAGACGAAAACAGGTTCTTTG
GGGGCGCGGGGAACTGCGCGATCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81555.1|4130454_4131870_+|55.5-kDa-and-49.5-kDa-sporulation-proteins	unknown	unknown	unknown
CP032698.1|AYG81561.1|4139288_4139552_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81565.1|4145778_4146324_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
CP032698.1|AYG81563.1|4141548_4143171_-|Low-affinity-putrescine-importer-PlaP	unknown	unknown	gnl|CDD|273331
CP032698.1|AYG81547.1|4116318_4117611_+|Multidrug-resistance-protein-MdtG	unknown	unknown	gnl|CDD|340887
CP032698.1|AYG81562.1|4139853_4140915_-|Anthranilate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234682
CP032698.1|AYG81554.1|4130002_4130290_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81558.1|4134639_4136055_+|hypothetical-protein	unknown	unknown	gnl|CDD|379143
CP032698.1|AYG81566.1|4146528_4147158_-|hypothetical-protein	unknown	unknown	gnl|CDD|240572
CP032698.1|AYG81556.1|4131979_4133182_+|L-2-hydroxyglutarate-oxidase-LhgO	unknown	unknown	gnl|CDD|183292
CP032698.1|AYG81550.1|4121099_4121924_+|hypothetical-protein	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG81549.1|4119402_4120725_-|NADH-dehydrogenase-like-protein	unknown	unknown	gnl|CDD|224172
CP032698.1|AYG81548.1|4117622_4119266_-|Phosphoserine-phosphatase-RsbU	unknown	unknown	gnl|CDD|369272
CP032698.1|AYG81552.1|4124198_4127390_-|Putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|226418
CP032698.1|AYG81557.1|4133764_4134565_+|tRNA-(guanine-N(7)-)-methyltransferase	unknown	unknown	gnl|CDD|234649
CP032698.1|AYG81553.1|4127539_4129663_-|hypothetical-protein	unknown	unknown	gnl|CDD|273676
CP032698.1|AYG81551.1|4122134_4124168_+|hypothetical-protein	unknown	unknown	gnl|CDD|214816
CP032698.1|AYG81559.1|4136543_4137650_-|Glycyl-glycine-endopeptidase-ALE-1	unknown	unknown	gnl|CDD|366703
CP032698.1|AYG81560.1|4138103_4139225_-|hypothetical-protein	unknown	unknown	gnl|CDD|369272
CP032698.1|AYG81564.1|4143284_4145582_-|ATP-dependent-RNA-helicase-RhlE	unknown	unknown	gnl|CDD|223587

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81565.1|4145778_4146324_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	9.24893e-10
CP032698.1|AYG81563.1|4141548_4143171_-|Low-affinity-putrescine-importer-PlaP	gnl|CDD|273331	TIGR00907, Choline_transport_protein, amino acid permease (GABA permease). [Transport and binding proteins, Amino acids, peptides and amines].	4.25407e-137
CP032698.1|AYG81547.1|4116318_4117611_+|Multidrug-resistance-protein-MdtG	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.69341e-60
CP032698.1|AYG81562.1|4139853_4140915_-|Anthranilate-phosphoribosyltransferase	gnl|CDD|234682	PRK00188, trpD, anthranilate phosphoribosyltransferase; Provisional.	4.34773e-145
CP032698.1|AYG81556.1|4131979_4133182_+|L-2-hydroxyglutarate-oxidase-LhgO	gnl|CDD|183292	PRK11728, PRK11728, L-2-hydroxyglutarate oxidase.	0
CP032698.1|AYG81566.1|4146528_4147158_-|hypothetical-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	1.89813e-48
CP032698.1|AYG81558.1|4134639_4136055_+|hypothetical-protein	gnl|CDD|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	5.45357e-48
CP032698.1|AYG81550.1|4121099_4121924_+|hypothetical-protein	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.09552e-10
CP032698.1|AYG81549.1|4119402_4120725_-|NADH-dehydrogenase-like-protein	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	1.05697e-94
CP032698.1|AYG81548.1|4117622_4119266_-|Phosphoserine-phosphatase-RsbU	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	5.25596e-49
CP032698.1|AYG81552.1|4124198_4127390_-|Putative-HTH-type-transcriptional-regulator	gnl|CDD|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	9.06492e-59
CP032698.1|AYG81557.1|4133764_4134565_+|tRNA-(guanine-N(7)-)-methyltransferase	gnl|CDD|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.06811e-86
CP032698.1|AYG81553.1|4127539_4129663_-|hypothetical-protein	gnl|CDD|273676	TIGR01536, Asparagine_synthetase_1, asparagine synthase (glutamine-hydrolyzing). This model describes the glutamine-hydrolysing asparagine synthase. A poorly conserved C-terminal extension was removed from the model. Bacterial members of the family tend to have a long, poorly conserved insert lacking from archaeal and eukaryotic sequences. Multiple isozymes have been demonstrated, such as in Bacillus subtilis. Long-branch members of the phylogenetic tree (which typically were also second or third candidate members from their genomes) were removed from the seed alignment and score below trusted cutoff. [Amino acid biosynthesis, Aspartate family].	6.87475e-05
CP032698.1|AYG81551.1|4122134_4124168_+|hypothetical-protein	gnl|CDD|214816	smart00776, NPCBM, This novel putative carbohydrate binding module (NPCBM) domain is found at the N-terminus of glycosyl hydrolase family 98 proteins.	2.64605e-37
CP032698.1|AYG81559.1|4136543_4137650_-|Glycyl-glycine-endopeptidase-ALE-1	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	8.21404e-35
CP032698.1|AYG81560.1|4138103_4139225_-|hypothetical-protein	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	3.93448e-39
CP032698.1|AYG81564.1|4143284_4145582_-|ATP-dependent-RNA-helicase-RhlE	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	1.16248e-118

Protein sequences

>CP032698.1|AYG81556.1|4131979_4133182_+|L-2-hydroxyglutarate-oxidase-LhgO
MTTYDCDVLVVGGGIVGLSTAYALTREAPGTRVTVLEKENGPARHQTGRNSGVIHSGIYYKPGSLKARFAVRGAAEMVEFCARHGIPHEVTGKLIVATERAELPRLHALVQRGRENGIPVRELGPPQIAAYEPEVRGLAAIHVGTTGVCDYGAVAARLAELSGAEVRYGAEVVHIDRRPSLGVAVRLADGTVLRARALVNCAGLHCDRVARLAGDDPGVRIVPFRGEYYELARPGLVKGLVYPVPDPAFPFLGVHLTRGVDGTVHVGPNAVPAAAREGYDWRTVRPRELAGTLAWPGSWRIARRHWRYGAGELHRSWSKRAFTDAVRRLLPSVREADLRPAPAGVRAQAVLRDGTLVDDFLIRSAPRTIHVLNAPSPAATASLPIGREVARRALAALPRP
>CP032698.1|AYG81555.1|4130454_4131870_+|55.5-kDa-and-49.5-kDa-sporulation-proteins
MSREQRGPNEKLGTVLALAGISNAGLARRVNDLGAQRGLTLRYDKTSVARWVSKGMVPQGAAPHLIAAAIGAKLGRPVPLHEIGLADADPAPEVGLAFPRDVSEAVRSATDLYRLDLAGRRAGGGIWQSLAGSFAVSAYATPASRWLITPADSSVARSVELTDLPPLKVGHSDVAKLREAAEDARRWDSKYGGGDWRSSMVPECLRVDAAPLLLGSYSDEVGRALFGATAELTRLAGWMAFDTGQQEAAQRYYIQALRLARAAADVPLGGYVLASMSLQATYRGFADEGVDLAQAAVERNRGLATARTMSFFRLVEARAHAKAGDGHPAEAALKAAEAWLERSRDGDCDPSWLGFYSYDRFAADAAECYRDLKAPRQVRRFTEQALSRPTEEFVRSHGLRLVVSAVAELESGNLDAACAAGTRAVEVAGRISSARTTEYVRDLLHRLEPYGDEPRVAELRERARPLLVTPA
>CP032698.1|AYG81554.1|4130002_4130290_-|hypothetical-protein
MARLFSVRPVADTGGRGPAAERLRRGAAGPVAAALPTCGRAPGRALSPVPQGSASMCGAWVGPLRGSSGLGDTAASIPAGGGPVREANSASRTVC
>CP032698.1|AYG81553.1|4127539_4129663_-|hypothetical-protein
MRWLVGWSSVAASFRAGAQGAGGYGTAGAVGEPDEGRTVHPVGAQLLWGDPDPLWAVGDWRPDEIRIVSVGADTRLAVLGCCAATDEELRVGLFAARGGALRHLTAWPGSYTAVAQVARRVTVVGDLAGARPVFYTPWAGGTAYGTAALPLADLIEAQLDIGHLAALLACPDVPEALGDSTPYAGVRRIPPGHALVLREGSREITGYEPVASLAVAAPQLAPVAAVDGVRDALVAAVRARLTAPRHAPETLPPDPGPVPGMGPAERRAARGGPAPGIGADLSGGPASATLALLAAGLPGVPGTVLGHGTGAGERLLAVTFNDLTVPGAGRQAELERAGAMAANPRLHHVVVTGGEEFLPYADLEGPLTDEPGPSLIAAPRHRRRLLSGSADHFTGSGARQVLDAHPARLADLLMDRQRRHLLRPATALAKAGGPSANSLFVPLTVYRAARRLARTPYRAGIESAADALREPSFDDATSPLSISLAALSWTRPGPAARWLTGEALAEVSARLMASATRPAPSQRPGQARASAALARYAADHRVLEQAAEVRSQRLHAPFLDNQVVRACRALPESLRVQPGARATILRTVLSASGVRDLPPGWGAPSHGPTATARAGLRHFADPLISLFEAPLLADAGLIEARTVRKAVRAAAAGEPLPLDGLADLISTELWLRRLLSRRGTCWTGTAAPRQRAVAGGVTPPRRPTLRS
>CP032698.1|AYG81552.1|4124198_4127390_-|Putative-HTH-type-transcriptional-regulator
MRYLILGATEAHEPDGTSIPLGGRRVRALLTALALRVPRAVPVATLIDDVWADDPPQDAPAALQALVGRLRRALGKDAVESGPAGYRLTAPRHAVDLFVFEERAAQGAAQLAAGEPERAATTLRAALALWRGPALCDLPEPDGAVRAEAQRLSARRNRIEADLRRGATHGLLPELTELLASYPYDETLHSQMIRTLVAEGRRADALAAYEQARRTLADALGTDPGPELAALHAELLAGGPAVERPAPAPSPRPEGNLRPRLTSFVGREPELASIQGDLATYRLVTLTGPGGTGKTRLAEQAASAARVDAWLVELAPLDDPGAVPGAVVSALGLRETTLLAREGQPGHDDPTARLADDLSRRPDTLLVLDNCEHVIDAAARLAETLLTRCPRLRILATSREPLGVPGETVRPVEPLPPAPAHRLFAERARAVRPDFDPGADPEAVAEICRRLDGLPLAIELAAARLRLLTPRQIADRLDDRFRLLTGGSRTVLPRQQTLRAVVDWSWDLLEEPERTVLRRASVFAGGWDLAAAQAVCAATDDLAALVEKSLVIAVPAPDGSGMRYRMLETIHEYATERAAETPQVLREAADAHTAYYRALVAEAEPLIRSAEQLPWIRCLETELDNIRAALRRTTTGRTADEEAATELVLNMGWFWWLRNYRTEGAGWGRAAAELAPLPDDECDPRYWPRLHLDLLRYFLLSDVERGHGLEDNGVQDRLAELRKAFEGGGPQAARFPGLLWPFATFHTDPPGLVRDSINGVVANCRRYGDDWATAVSLMFRTHMSIDMPGGLEGVDEDLAELRELGRRVGDRWMRAQVAGAAAEAAMTRGLSEVARPAYEEALQLAREVGAHQETPFLTARVGELAYRQGDLDAAEKSLTEAAADALRYRVAEALPYVHSLLATIALDRGDTVTALALRDQALDFAEKGPPGAPPHFVALLDALDARTTAIESGPLAGLRGMANALRTAAGGRCTEHVLAHLAERAAQFLGDLGEHGRALRLLAAASTWRADIPRSVPERAIEESIRLRAREALTPERYEAEYAAGSPLTPTEIPPILDEVTEA
>CP032698.1|AYG81551.1|4122134_4124168_+|hypothetical-protein
MGVEERDESLSGGGGPESGGPDGGRPPRQVPSQGGFGPGAPSGPAPVPGQAAKGSGYEHAGDFGLAGGAGLGGTVLPGPWGPMDGIGDPGSSVPTQREGGLRDGVTLDLPEVGQSDADLIHAMRAGDDSAYEELFRRHSEAVRRYARTCCRDAHTADDLTAEVFARTLQAVRGGAGPEHAVRAYLMTTVRRVAATWTRTAKREHLVDDFAVFAQQSARSTEAFDDDTIDLGAEVRAMHEAEQTLAMQAFRSLPERWQAVLWHTTVEEESPSEIAPLFGLTANATAVLASRAREGLKQAYLQAHVSTALTSGGDCARYADRLGAYARGGLRMRAERGLSKHLEECAKCRVAVIELKDVNAGIPALLPVAVIGWFAAGFSLKAAGVVAGGAAGAAGAGAAAAATGSGASSGAAGGAAVSEGLGAPAKAGIAAAVAVAVAAGIVFALTGNDAPAPKPDAKPPAVVPAVPHKPPPAPEPPAAPAAAPTPPPRPAPKKPAARPLPPTPTRPAPTPPRPTPPKPTPPKPTPAKPPPPPAPSVFQVNRLEYGLLGDGTKPEVRLGGSSWLWQRSGMSIDGHRYPHGVTVHGRSSVTIDLNRQCRTYDAYAGVDDLMAGLGAVRFSLYGDATRLWQSPVVHAGDPAVPVHADIAGRRTIRLVVEPAGPFGGAALADWAQSRIGCA
>CP032698.1|AYG81550.1|4121099_4121924_+|hypothetical-protein
MHIQDSHWQTAVASSDGHGRVGTAPGAGGSRSAPLRVDAQRNLEHVLRAAREVFGELGYGAPMEDVARRARVGVGTVYRRFPSKDVLVRRIAEEETSRLTDQARTALGQENEPWSALSRFLRTSVASGAGRLLPPQVLRVGVDAEETEGVRPEAPRDETSRPDGVRDGFDEARVPQQRQVGSAEQGAAWGRVIAQRTAPEQELDDPGAAELLDVVGQLVDRARAAGELRVDVTVADVLLVIATAAPSLPDANQQAAASSRLLDILLEGLRSRPS
>CP032698.1|AYG81549.1|4119402_4120725_-|NADH-dehydrogenase-like-protein
MYTALRLQRKLKTELRAGTAEITVVAPDPYMTYQPFLPEAAAGNISPRHVVVPLRRVLDKCRIVIGEADRIDHAHRTATVTTLASPEDGTGAIRLTYDELVIAPGSISRTLPVPGLADYAIGFKTVEEAIGLRNHVIEQMDIASSTRDPAVRDAALTFVVVGGGYAGVEALAELEDMARYTARYYHNIRPEDLKWILVEASDRILPEVGEEMGRYAIRELRSRNIDVRLETRLDSCENRIAVLSDGARFPTRTVVWTAGVKPAPLLAATDLPLNERGRIECTAQLRVAGTDHAWAGGDAAAVPDLTSREKGKECAPNAQHAVRQAKVLAENVAAAVRGGEPVEYRHSYAGSVASLGLHKGVAHVYGRKLKGYPAWFMHRAYHLSRVPTFNRKARVLAEWTLAGLFKREIVSLGSLEHPRAEFEIAAGGGPPGKGPAPQDT
>CP032698.1|AYG81548.1|4117622_4119266_-|Phosphoserine-phosphatase-RsbU
MNFTRWSARLPGTQRRAAARTDRGSVPAARGESGSQPEPWTDDTDEAAEPPVLDDLSVRDVLGQLPALVALVHGPEHRVAYVNDAYAAAFGVRPLGAPAAKTLPELDELGLLPLMDQVLRSGTSRTVKSRKTQSAGSYTVTCTPVTIPNHAEGGVLVYAADVTDHAEAAERLRASERRHRETAVTLQRSLLPQELEQPDDLRVAATYQPGGTDAAVGGDWYDVITLGAGRTALVIGDVMGRGVRAAAVMGQLRTAVRAYARLDLPPHEVLQLLDGLAAEIDASQIATCVYAVHDPNEGRLVYASAGHLPVLVRHEDGTVHRAEDPTGPPLGTGGWLHTSGSIALPPGATAVLYTDGLVERRREDIDEGVAALERALSGAVGTPQVVCDRLLRALGVTAEHDDDVAVLVCQHPARTGHAAELFHNAALDLLGGIEAAPRARAFASGVLSSWRFPVELRDLGVLAVSELVANSLQHGTPPMRLRLRRTDRRLIIEVTDGDDHLPRRRRADPADEAGRGISIVATIASSWGSRRTPGGGKAVWCEFALPG
>CP032698.1|AYG81547.1|4116318_4117611_+|Multidrug-resistance-protein-MdtG
MTKAMGAAMRRIQAGNALSAFGLGFTVPYLYVYVAQVRDLGATTAGVVLAVFAMAALVVLPFTGRVIDRRGPLPVLVGAAVLASAGALSMGFASSVPAAVASAALLGAGTAVMQPALATMIVWCSGPATRTRAFALQFFLQNLGLGIGGLIGGQLVDQSRPASFTLLFSIEAVMFLVLAGVAGSAKMPRSMPLSDARPTGEQGAGVGIRAILGHRAMVQLCVLGFVVFFACYGQFESGLAAYGTEAAGIQPSTLGIALAANTAVIVVAQFLVLKFVERRRRSRVIAAVGLIWAFAWIVAGYAGLGHGSQAMATAAFVSTYALFGLGEAMLSPTVAPLVADLAPESMVGQYNSAFALVKQLALAVGPAVGGPMGAALHGPYIVTFVLFSLGITVLALRLGKGLTPAQDQPVLAAASRVVSVHKPEPTPANA
>CP032698.1|AYG81557.1|4133764_4134565_+|tRNA-(guanine-N(7)-)-methyltransferase
MSEQPQTPEPPAPRTEKVLPRDKAPRFPGGPAADPAGSHHERRIRSFQPRRSRVTTGQGEYLERLWPVWGFDIDGLREIDLVEMFEGLPVVLEIGFGMGEATAQMAADDPGTGILAVDVHTPGQGNLLGLAERGGLNNVRVANGDAIILLREMLRPDALDGLRVYFPDPWPKKRHHKRRLIQPEFLSLAATRMKPGAVLHCATDWEDYAEQMLEVLDAHPDFENTVDGGGYAPRPAFRPLTRFEGQGLDKGHVVHDLLFRRVGHGG
>CP032698.1|AYG81558.1|4134639_4136055_+|hypothetical-protein
MSFESLPHRPHPGQAPQQAGSAFSAQPVPACADEPRFDAVPPDRAKWRYRPRRDFWRSKAVRAGALITLLALCGLVIFALVRDETGTEGFLVGLGLAVLPVPLLAAAFRWLDRVDPGPWRNLFFALAWGACAAALVAIIANSFATRWIATATADPSSADHLGAGVIAPIVEESAKAAAVLLLFLFRRRDFKSLVDGVVFAGFTATGFAFTENILYLGNAFGEDQASHSGGLASTTAATFFVRVVMSPFAHPLFTVMTGIGFGVAALAPSGRRLRRVVFPLLGLVCAMGMHALWNSSTLFGAYGFLIVYGGFMVPAFGLVTWLAIWSRQRELRTVAAELPAYAAAGWLGLAEPFALSSMRARATAREFAQHRLGGKSAARAVAEYEAFATALAFLRHRAYRSAGATGPGPDFAAREQELLHHLWERKPVAGPALLYAAGATGRAWPPPHPGPPSPYPYWPPTPPPTYNPYLT
>CP032698.1|AYG81559.1|4136543_4137650_-|Glycyl-glycine-endopeptidase-ALE-1
MAANEPALGTPLPAFPSTTLDPARPQPLYGDAPGETETWEEWDPTEESVRPVRGRHRVAKQRGGGLARSSTVLGVGVIAAVGAGGMASAQSKPPVSISLPDSLSASLPDLGSLPGVGELVPHHAPDSLTSGAAQADQKIAAAPLTMTGLSTGEAERGATDAGEALRARILQQAAQQKAGAAAEAKAAAQQAAAQKAAREAAAQQDAARAKAAAEKKAQEEAAEKKAEEERLAKLAASYSLPVGSNTLTSTFGEAGSMWSSGHHTGLDFAAPTGTPLKAIHSGTIVSAGWAGAYGYRTVVKLDDGSELWYCHQSSIAVSAGQRVATGEVVGRVGATGNVTGPHLHLEVHTPSGTGIDPMTWLQSKGLAP
>CP032698.1|AYG81560.1|4138103_4139225_-|hypothetical-protein
MRQRAEGDRRLVRALPVLLIVVGFVFDASTPPDLTAAALFAGAPVAAAPFYSDRGTAAVGAGSVAAVVALWFIHDLPNLGEGASELFTVLTVSALALVINRILRHSGEQLASARVIAETAQRAVLPTPAARIGGLHVAARYEAAQADAFIGGDLFAVQDTPYGVRLIVGDVRGKGLQAVEAVAVVIGAFREAAEQESSLEAVTQRLERALAREGTRRDRLDAVEGFTTALLAEIPRGESTVRLVNRGHPEPFLLHADGSLDALVPSEPALPLGMSDLGVWPDRADARPFPAGSMLLLYTDGLSEARDKAGVFYQPGARLSGAIFPGPEEVLDALVDDVRRYTGGGSSDDMALLAVARPAEGQPERRRTVQIVK
>CP032698.1|AYG81561.1|4139288_4139552_-|hypothetical-protein
MRRRVLAGVLLVVGLGAGLSGCQEAGGPVPVVVRGPAVGVTVPAHGCRLNRDGWAELPCVPERAANHRHTRGSCVRGRPGPHRCRRH
>CP032698.1|AYG81562.1|4139853_4140915_-|Anthranilate-phosphoribosyltransferase
MIEAGRTWRHLLAVLLRGEDLGADDARWAMRQVMDDAADPAQLAGFLVALRAKGESAEEIHGLLDALMERVVPLPVDGADVVDIVGTGGDGAHTVNVSTMAAVVVAGAGVPVVKHGGRSVSSKAGAADVLEALGLPLDLTPDAVARCVRETGIGFTFAPRFHHGLRHAGPVRKSLGVPTVINYLAPLTNPARPRTAVVGCSNTALAPVLADVLAARGASALVVRGDDGLDEITTAAPTRAWVAAAGRVRQVGLDTAEFGLPRCAPDALRGGDAAYNARAVHRVMDGETGPVRDAVLANAAGALAAYRGFGDRDLPDAFAAALDEARHALDSGAAARTLKTWLDLARSLRGPAR
>CP032698.1|AYG81563.1|4141548_4143171_-|Low-affinity-putrescine-importer-PlaP
MSRGPRIRRSVRFRPRHGAWSAPGEGIAGGMTNDASTNSPEKQGSAGAEGSAGVATTDEERLAQLGYKQVLARRMSAFSNYAVSFTIISVLSGCLTMYAYGMKTGGPALITWGWVAVGLMTLVVGLAMAEICSAYPTSAGLYFWAHRLAPPRSAAAWAWFTGWFNVLGQIAVTAGVDFGAASFLGAYLNLQFGFEVTPARTILLFAAILLLHGLLNTFGVRIVALLNSVSVWWHVLGVVAIVAALLFVPDTHQSTSFVFTRFVNETGFTNGVYVVLIGLLMAQYTFTGYDASAHMTEETHDASTAGPRGIVRSIWTSWIAGFVLLLGFTYAIGSYDTQLDSATGAPPAQILLDSLGETGGKLLLLVVIGAQLFCGMASVTANSRMIYAFSRDGALPFSRLWHTVSPRTRTPVAAVWLAAGAALVLGLPYLINVTAYAAVTSIAVIGLYIAYVIPTLLRLFRGDAFTPGPWHLGRWSRPVGIVAVAWVTVITVLFMLPQVSPVTWETFNYAPLAVLAVLGFATAWWLASARHWFLRGVRGE
>CP032698.1|AYG81564.1|4143284_4145582_-|ATP-dependent-RNA-helicase-RhlE
MSISSTDHSVLPENENNDSIEAVQVVEARENDVVEAVAASDVIEVVEIVESEADENDENAEPTVTFAALGLPEGVVRKLAQNGVTSPFPIQAATIPDALAGKDILGRGRTGSGKTLSFGLPTLAQLAGGHTEKKKPRAIILTPTRELAMQVADALQPYGDVLGLKMKVVCGGTSMSNQIYALERGVDVLVATPGRLRDLINRGACSLANVQVAVLDEADQMSDLGFLPEVTELLDQIPGGGQRMLFSATMENEISTLVKRYLTNPVTHEVDSAQGNVSTMTHHVLVVKPKDKAPVTAAIAARKGRTIIFVRTQLGADRIAEQLCESGVKADALHGGMTQGARTRVLEDFKKGYVNALVATDVAARGIHVDGIDLVLNVDPAGDHKDYLHRSGRTARAGKSGVVVSLSLPHQRRQIFRLMEDAGVDASRHIIQSAGAFDPEVAEITGARSLTEVQADSANNSAKQAEREVADLTKQLERLTRRAGELREEADRLVARAARERGEDPEAAVAEVAAEAEAEVAAAAAAAAVPVQQESREERGGFQRRDDRGNFERRDNRGGDRGERGGFNRDRRDERPSGGFNRGGGDRPFNRDRRDERPAGGGFRRDDRPSGGFRRDDRPSGGSNRDDRGGDRGGFRRDDRPSGGFRRDERPSGGFNRDDRGGDRGGFRRDDRPSGGFNRDDRGGERGGFNRDRRDERPSGGFNRGGGDRPFNRDRRDERPAGGGFRTGGHDRPQGRRDDHRGTGTGTATGSFGRRDDKPRWKRNG
>CP032698.1|AYG81565.1|4145778_4146324_-|hypothetical-protein
MRQLTTPVRLAELAVTVLVLTASAGCMSVSEDEGKPKPSVSAGQHGGAAASDEGKGGSGAGREHGGKRDPKAPGGSAGKPSAGGSPGASGPAAPSAGANPKPGGPGPAKPSPGAPSKPAPSPTRSVPAPPPVSPPAPPSSSPPPAASPSTTPGADTHNTALHRNQPPIDPEPTASPQVGPV
>CP032698.1|AYG81566.1|4146528_4147158_-|hypothetical-protein
MARLGALQRVGDVRSIWDAGRYRQNGFRGGPAAPTGDRHRTDDERHRGDPDGAARTGPDQDGPDQGEPHPHSPEPHPPEPHSAPTPQVTHNGRVLEMTREEFEELVGEALDRIPPELTRLMDNVAVFVEDEPAPDDPELLGLYEGTPLTDRGEWYAGVLPDRITIYRGPTLRMCETREEVVAETEVTVVHEIAHHFGIDDERLHALGYG

Crispr_ID: CP032698_40

• CRISPR_ID: CP032698_40
• CRISPR_location: 4147851-4147949
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_40

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGG	CRISPRCasFinder

spacers of CP032698_40

>40.1|4147875|51|CP032698|CRISPRCasFinder
GGGCCGGAACCGACCAACGCGCTGCACGGGCGGGTGGGTGGGAAAACGGGC

CRISPR arrays and Neighbor proteins around CP032698_40

CRISPR arrays

The CRISPR arrays of CP032698_40

>merge|CP032698|40|4147851-4147949|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGGCCGGAACCGACCAACGCGCTGCACGGGCGGGTGGGTGGGAAAACGGGCCGGGGTTTGGGGCGGAGCCCCAGG

>CP032698|40|31|4147851-4147949|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGG	GGGCCGGAACCGACCAACGCGCTGCACGGGCGGGTGGGTGGGAAAACGGGC
CGGGGTTTGGGGCGGAGCCCCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81561.1|4139288_4139552_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81565.1|4145778_4146324_-|hypothetical-protein	unknown	unknown	gnl|CDD|237030
CP032698.1|AYG81563.1|4141548_4143171_-|Low-affinity-putrescine-importer-PlaP	unknown	unknown	gnl|CDD|273331
CP032698.1|AYG81564.1|4143284_4145582_-|ATP-dependent-RNA-helicase-RhlE	unknown	unknown	gnl|CDD|223587
CP032698.1|AYG81562.1|4139853_4140915_-|Anthranilate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234682
CP032698.1|AYG81572.1|4155215_4155422_-|hypothetical-protein	unknown	unknown	gnl|CDD|133390
CP032698.1|AYG81569.1|4149747_4150170_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81571.1|4154641_4154815_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81566.1|4146528_4147158_-|hypothetical-protein	unknown	unknown	gnl|CDD|240572
CP032698.1|AYG81558.1|4134639_4136055_+|hypothetical-protein	unknown	unknown	gnl|CDD|379143
CP032698.1|AYG81576.1|4158725_4159820_-|Phosphoribosylformylglycinamidine-cyclo-ligase	unknown	unknown	gnl|CDD|235439
CP032698.1|AYG81574.1|4156926_4158015_+|Valine-dehydrogenase	unknown	unknown	gnl|CDD|223411
CP032698.1|AYG81568.1|4148859_4149624_-|Disulfide-bond-formation-protein-D	unknown	unknown	gnl|CDD|372611
CP032698.1|AYG81573.1|4155918_4156761_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81557.1|4133764_4134565_+|tRNA-(guanine-N(7)-)-methyltransferase	unknown	unknown	gnl|CDD|234649
CP032698.1|AYG81575.1|4158295_4158559_+|hypothetical-protein	unknown	unknown	gnl|CDD|378620
CP032698.1|AYG81560.1|4138103_4139225_-|hypothetical-protein	unknown	unknown	gnl|CDD|369272
CP032698.1|AYG81570.1|4150254_4154175_+|hypothetical-protein	unknown	unknown	gnl|CDD|182986
CP032698.1|AYG81559.1|4136543_4137650_-|Glycyl-glycine-endopeptidase-ALE-1	unknown	unknown	gnl|CDD|366703
CP032698.1|AYG81567.1|4148029_4148863_-|hypothetical-protein	unknown	unknown	gnl|CDD|223856

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81568.1|4148859_4149624_-|Disulfide-bond-formation-protein-D	gnl|CDD|372611	pfam13462, Thioredoxin_4, Thioredoxin.	3.35274e-29
CP032698.1|AYG81563.1|4141548_4143171_-|Low-affinity-putrescine-importer-PlaP	gnl|CDD|273331	TIGR00907, Choline_transport_protein, amino acid permease (GABA permease). [Transport and binding proteins, Amino acids, peptides and amines].	4.25407e-137
CP032698.1|AYG81564.1|4143284_4145582_-|ATP-dependent-RNA-helicase-RhlE	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	1.16248e-118
CP032698.1|AYG81562.1|4139853_4140915_-|Anthranilate-phosphoribosyltransferase	gnl|CDD|234682	PRK00188, trpD, anthranilate phosphoribosyltransferase; Provisional.	4.34773e-145
CP032698.1|AYG81572.1|4155215_4155422_-|hypothetical-protein	gnl|CDD|133390	cd04762, HTH_MerR-trunc, Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins. Proteins in this family mostly have a truncated helix-turn-helix (HTH) MerR-like domain. They lack a portion of the C-terminal region, called Wing 2 and the long dimerization helix that is typically present in MerR-like proteins. These truncated domains are found in response regulator receiver (REC) domain proteins (i.e., CheY), cytosine-C5 specific DNA methylases, IS607 transposase-like proteins, and RacA, a bacterial protein that anchors chromosomes to cell poles.	3.77068e-14
CP032698.1|AYG81566.1|4146528_4147158_-|hypothetical-protein	gnl|CDD|240572	cd12952, MMP_ACEL2062, Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein. The subfamily includes an uncharacterized protein from Acidothermus cellulolyticus (ACEL2062) and its homologs from bacteria. Although its biological role remains unclear, ACEL2062 contains a minimal metalloprotease (MMP)-like domain consisting of 3-stranded mixed 2-beta sheets and a HExxHxxGxxD/S (x could be any amino acid) motif. It may belong to a superfamily of bacterial zinc metallo-peptidases, which is characterized by a conserved HExxHxxGxxD motif.	1.89813e-48
CP032698.1|AYG81558.1|4134639_4136055_+|hypothetical-protein	gnl|CDD|379143	pfam13367, PrsW-protease, Protease prsW family. This is a family of putative peptidases, possibly belonging to the MEROPS M79 family. PrsW, appears to be a member of a widespread family of membrane proteins that includes at least one previously known protease. PrsW appears to be responsible for Site-1 cleavage of the RsiW anti-sigma factor, the cognate anti-sigma factor, and it senses antimicrobial peptides that damage the cell membrane and other agents that cause cell envelope stress, The three acidic residues, E75, E76 and E95 in Aflv_1074, appear to be crucial since their mutation to alanine renders the protein inactive. Based on predictions of the bioinformatics programme TMHMM it is likely that these residues are located on the extracytoplasmic face of PrsW placing them in a position to act as a sensor for cell envelope stress.	5.45357e-48
CP032698.1|AYG81576.1|4158725_4159820_-|Phosphoribosylformylglycinamidine-cyclo-ligase	gnl|CDD|235439	PRK05385, PRK05385, phosphoribosylaminoimidazole synthetase; Provisional.	8.61576e-178
CP032698.1|AYG81574.1|4156926_4158015_+|Valine-dehydrogenase	gnl|CDD|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	1.46548e-88
CP032698.1|AYG81565.1|4145778_4146324_-|hypothetical-protein	gnl|CDD|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	9.24893e-10
CP032698.1|AYG81557.1|4133764_4134565_+|tRNA-(guanine-N(7)-)-methyltransferase	gnl|CDD|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.06811e-86
CP032698.1|AYG81575.1|4158295_4158559_+|hypothetical-protein	gnl|CDD|378620	pfam11273, DUF3073, Protein of unknown function (DUF3073). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.17006e-20
CP032698.1|AYG81560.1|4138103_4139225_-|hypothetical-protein	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	3.93448e-39
CP032698.1|AYG81570.1|4150254_4154175_+|hypothetical-protein	gnl|CDD|182986	PRK11131, PRK11131, ATP-dependent RNA helicase HrpA; Provisional.	0
CP032698.1|AYG81559.1|4136543_4137650_-|Glycyl-glycine-endopeptidase-ALE-1	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	8.21404e-35
CP032698.1|AYG81567.1|4148029_4148863_-|hypothetical-protein	gnl|CDD|223856	COG0785, CcdA, Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones].	5.71192e-24

Protein sequences

>CP032698.1|AYG81566.1|4146528_4147158_-|hypothetical-protein
MARLGALQRVGDVRSIWDAGRYRQNGFRGGPAAPTGDRHRTDDERHRGDPDGAARTGPDQDGPDQGEPHPHSPEPHPPEPHSAPTPQVTHNGRVLEMTREEFEELVGEALDRIPPELTRLMDNVAVFVEDEPAPDDPELLGLYEGTPLTDRGEWYAGVLPDRITIYRGPTLRMCETREEVVAETEVTVVHEIAHHFGIDDERLHALGYG
>CP032698.1|AYG81565.1|4145778_4146324_-|hypothetical-protein
MRQLTTPVRLAELAVTVLVLTASAGCMSVSEDEGKPKPSVSAGQHGGAAASDEGKGGSGAGREHGGKRDPKAPGGSAGKPSAGGSPGASGPAAPSAGANPKPGGPGPAKPSPGAPSKPAPSPTRSVPAPPPVSPPAPPSSSPPPAASPSTTPGADTHNTALHRNQPPIDPEPTASPQVGPV
>CP032698.1|AYG81564.1|4143284_4145582_-|ATP-dependent-RNA-helicase-RhlE
MSISSTDHSVLPENENNDSIEAVQVVEARENDVVEAVAASDVIEVVEIVESEADENDENAEPTVTFAALGLPEGVVRKLAQNGVTSPFPIQAATIPDALAGKDILGRGRTGSGKTLSFGLPTLAQLAGGHTEKKKPRAIILTPTRELAMQVADALQPYGDVLGLKMKVVCGGTSMSNQIYALERGVDVLVATPGRLRDLINRGACSLANVQVAVLDEADQMSDLGFLPEVTELLDQIPGGGQRMLFSATMENEISTLVKRYLTNPVTHEVDSAQGNVSTMTHHVLVVKPKDKAPVTAAIAARKGRTIIFVRTQLGADRIAEQLCESGVKADALHGGMTQGARTRVLEDFKKGYVNALVATDVAARGIHVDGIDLVLNVDPAGDHKDYLHRSGRTARAGKSGVVVSLSLPHQRRQIFRLMEDAGVDASRHIIQSAGAFDPEVAEITGARSLTEVQADSANNSAKQAEREVADLTKQLERLTRRAGELREEADRLVARAARERGEDPEAAVAEVAAEAEAEVAAAAAAAAVPVQQESREERGGFQRRDDRGNFERRDNRGGDRGERGGFNRDRRDERPSGGFNRGGGDRPFNRDRRDERPAGGGFRRDDRPSGGFRRDDRPSGGSNRDDRGGDRGGFRRDDRPSGGFRRDERPSGGFNRDDRGGDRGGFRRDDRPSGGFNRDDRGGERGGFNRDRRDERPSGGFNRGGGDRPFNRDRRDERPAGGGFRTGGHDRPQGRRDDHRGTGTGTATGSFGRRDDKPRWKRNG
>CP032698.1|AYG81563.1|4141548_4143171_-|Low-affinity-putrescine-importer-PlaP
MSRGPRIRRSVRFRPRHGAWSAPGEGIAGGMTNDASTNSPEKQGSAGAEGSAGVATTDEERLAQLGYKQVLARRMSAFSNYAVSFTIISVLSGCLTMYAYGMKTGGPALITWGWVAVGLMTLVVGLAMAEICSAYPTSAGLYFWAHRLAPPRSAAAWAWFTGWFNVLGQIAVTAGVDFGAASFLGAYLNLQFGFEVTPARTILLFAAILLLHGLLNTFGVRIVALLNSVSVWWHVLGVVAIVAALLFVPDTHQSTSFVFTRFVNETGFTNGVYVVLIGLLMAQYTFTGYDASAHMTEETHDASTAGPRGIVRSIWTSWIAGFVLLLGFTYAIGSYDTQLDSATGAPPAQILLDSLGETGGKLLLLVVIGAQLFCGMASVTANSRMIYAFSRDGALPFSRLWHTVSPRTRTPVAAVWLAAGAALVLGLPYLINVTAYAAVTSIAVIGLYIAYVIPTLLRLFRGDAFTPGPWHLGRWSRPVGIVAVAWVTVITVLFMLPQVSPVTWETFNYAPLAVLAVLGFATAWWLASARHWFLRGVRGE
>CP032698.1|AYG81562.1|4139853_4140915_-|Anthranilate-phosphoribosyltransferase
MIEAGRTWRHLLAVLLRGEDLGADDARWAMRQVMDDAADPAQLAGFLVALRAKGESAEEIHGLLDALMERVVPLPVDGADVVDIVGTGGDGAHTVNVSTMAAVVVAGAGVPVVKHGGRSVSSKAGAADVLEALGLPLDLTPDAVARCVRETGIGFTFAPRFHHGLRHAGPVRKSLGVPTVINYLAPLTNPARPRTAVVGCSNTALAPVLADVLAARGASALVVRGDDGLDEITTAAPTRAWVAAAGRVRQVGLDTAEFGLPRCAPDALRGGDAAYNARAVHRVMDGETGPVRDAVLANAAGALAAYRGFGDRDLPDAFAAALDEARHALDSGAAARTLKTWLDLARSLRGPAR
>CP032698.1|AYG81561.1|4139288_4139552_-|hypothetical-protein
MRRRVLAGVLLVVGLGAGLSGCQEAGGPVPVVVRGPAVGVTVPAHGCRLNRDGWAELPCVPERAANHRHTRGSCVRGRPGPHRCRRH
>CP032698.1|AYG81560.1|4138103_4139225_-|hypothetical-protein
MRQRAEGDRRLVRALPVLLIVVGFVFDASTPPDLTAAALFAGAPVAAAPFYSDRGTAAVGAGSVAAVVALWFIHDLPNLGEGASELFTVLTVSALALVINRILRHSGEQLASARVIAETAQRAVLPTPAARIGGLHVAARYEAAQADAFIGGDLFAVQDTPYGVRLIVGDVRGKGLQAVEAVAVVIGAFREAAEQESSLEAVTQRLERALAREGTRRDRLDAVEGFTTALLAEIPRGESTVRLVNRGHPEPFLLHADGSLDALVPSEPALPLGMSDLGVWPDRADARPFPAGSMLLLYTDGLSEARDKAGVFYQPGARLSGAIFPGPEEVLDALVDDVRRYTGGGSSDDMALLAVARPAEGQPERRRTVQIVK
>CP032698.1|AYG81559.1|4136543_4137650_-|Glycyl-glycine-endopeptidase-ALE-1
MAANEPALGTPLPAFPSTTLDPARPQPLYGDAPGETETWEEWDPTEESVRPVRGRHRVAKQRGGGLARSSTVLGVGVIAAVGAGGMASAQSKPPVSISLPDSLSASLPDLGSLPGVGELVPHHAPDSLTSGAAQADQKIAAAPLTMTGLSTGEAERGATDAGEALRARILQQAAQQKAGAAAEAKAAAQQAAAQKAAREAAAQQDAARAKAAAEKKAQEEAAEKKAEEERLAKLAASYSLPVGSNTLTSTFGEAGSMWSSGHHTGLDFAAPTGTPLKAIHSGTIVSAGWAGAYGYRTVVKLDDGSELWYCHQSSIAVSAGQRVATGEVVGRVGATGNVTGPHLHLEVHTPSGTGIDPMTWLQSKGLAP
>CP032698.1|AYG81558.1|4134639_4136055_+|hypothetical-protein
MSFESLPHRPHPGQAPQQAGSAFSAQPVPACADEPRFDAVPPDRAKWRYRPRRDFWRSKAVRAGALITLLALCGLVIFALVRDETGTEGFLVGLGLAVLPVPLLAAAFRWLDRVDPGPWRNLFFALAWGACAAALVAIIANSFATRWIATATADPSSADHLGAGVIAPIVEESAKAAAVLLLFLFRRRDFKSLVDGVVFAGFTATGFAFTENILYLGNAFGEDQASHSGGLASTTAATFFVRVVMSPFAHPLFTVMTGIGFGVAALAPSGRRLRRVVFPLLGLVCAMGMHALWNSSTLFGAYGFLIVYGGFMVPAFGLVTWLAIWSRQRELRTVAAELPAYAAAGWLGLAEPFALSSMRARATAREFAQHRLGGKSAARAVAEYEAFATALAFLRHRAYRSAGATGPGPDFAAREQELLHHLWERKPVAGPALLYAAGATGRAWPPPHPGPPSPYPYWPPTPPPTYNPYLT
>CP032698.1|AYG81557.1|4133764_4134565_+|tRNA-(guanine-N(7)-)-methyltransferase
MSEQPQTPEPPAPRTEKVLPRDKAPRFPGGPAADPAGSHHERRIRSFQPRRSRVTTGQGEYLERLWPVWGFDIDGLREIDLVEMFEGLPVVLEIGFGMGEATAQMAADDPGTGILAVDVHTPGQGNLLGLAERGGLNNVRVANGDAIILLREMLRPDALDGLRVYFPDPWPKKRHHKRRLIQPEFLSLAATRMKPGAVLHCATDWEDYAEQMLEVLDAHPDFENTVDGGGYAPRPAFRPLTRFEGQGLDKGHVVHDLLFRRVGHGG
>CP032698.1|AYG81567.1|4148029_4148863_-|hypothetical-protein
MTPNIGYFAAFLGGLLALLSPCSALLLPAFFAYSISSRTKLLARTGIFYAGLATTLVPLGAAGSYAGRLFYGHRDALVLFGGWLIIVLGVAQIVGMGFASRRMTELSGRIRPTTALSVYALGAVYGLAGFCAGPILGSVLTVAAVSGSPLYGGLLLAVYALGMAVPLFLLALLWERFELGGRTWLRGRVVRVARFELHTTSLLSGLFFIALGALFLAYDGATGLPGVLDVDESYAVEEWARGVGGWVPDWALLLVVVGVVGLLLTTRARRPKPPPRS
>CP032698.1|AYG81568.1|4148859_4149624_-|Disulfide-bond-formation-protein-D
MSRPKTQSKQTARKPAKSRKQPYLIGAAVLVVAGVLGMASYQVSAPDPRPAVDGSGAAAASDPAPADAHPELTGLARRDAKDPLAQGRADAPVVMIEYADFKCSYCGKFARDTEPELVKKYVDDGTLRIEWRNFPIFGAESEAAARGAWAAGQQGRFWQFHAAAYARDAKEKGFGGDRLKELAKEAGVPDAARFAADLDGEAAKAAVKKDQDEAYALGASSTPSFLINGTPLAGAQPMDSFAQVIDAAARTAKK
>CP032698.1|AYG81569.1|4149747_4150170_-|hypothetical-protein
MPRSRTPRRRLTAVVLMVLGVLAVALFGPLPSASAAEPVSAAASATSAVSVAATAPAGEASAPVFTSGASTPGCRRGGAHHGSDPAAPVRARTAHDQAPVLEDRLAPVALCGLYAAHRNPPVRGPVLGAPTPVELSVLRV
>CP032698.1|AYG81570.1|4150254_4154175_+|hypothetical-protein
MSTSFADLQPLLDGASLRDAHRLGRRLEGARRIRKPEARQAVLDEIAAEAQKSADRVARRSARMPAITYPEQLPVSQKKDEILQAIRDHQVVIVAGETGSGKTTQIPKICLELGRGVRGMIGHTQPRRIAARTVADRIAEELNTPLGEAVGWKVRFTDQVDPNATFVKLMTDGILLAEIQTDRELRGYDTIIIDEAHERSLNIDFLLGYLAQLLPKRPDLKVVITSATIDPERFSRHFGNAPIVEVSGRTYPVEVRYRPLLEEDSEDADRDQITAICDAVDELQSEGPGDILVFLSGEREIRDTADALNKKNLRSTEVLPLYARLSHAEQHRVFQQHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSHRTKVQRLPIEPVSQASANQRKGRCGRTSDGICIRLYSEDDFLTRPEFTDAEILRTNLASVILQMTAAGLGDIEKFPFIDPPDHRNIRDGVQLLQELGALDPSEKDPKKRLTEQGRKLSQLPVDPRLARMVLEADRNGCVREVMVIAAALSIQDPRERPSDKQAQADQQHARFKDETSDFLAYLNLWRYVREQQKERGSSSFRRMCKQEYLNFLRIREWQDIYSQLRTVAKTMGIHLNEQDAPEQSVHTSLLAGLLSHIGLKDTDKNEYLGARSAKFAIFPGSALFKKQPKLVMSAELVETSRLWARVNAKVEPEWIEPLAQHLVKRTYSEPHWEKDQAAVMAYERVTLYGVPIVANRKVNYGRIDPEASRELFIRNALVEGDWRTHHKFFADNRKLLTEVEELEHRARRRDILVDDETLYDFYDRRVPDHVVSGAHFDSWWKQKRREEPELLDFEREMLINEKAGAVTKDDYPDSWRQGPLKLRVTYQFEPGADADGVTVHVPLQVLNQVTDEGFDWQIPGLREEVVTELIRSLPKPIRRHYVPAPNYAAKFLDRAVPLQEPLPVTLARELQRMVGVPVTADDFDLSRVPDHLKITFRIVDERRRKLAEDKDLEALKLQLRPKARKALSQAAAATAGPSGESIERSGLTDWTIGTLTKVFETRRAGQPVKAFPALVDAGESVSVRLFDTEAEQRQAMWRGTRKLILLGIPVNPAKFASDKLTNQQKLALSRNPHGSIQALFDDCATAAADKLIADHGGPAWDEKSFRALYDKVRADLVDATVHTVNQVQQILAAWQACERRLKATNSLTLVANVTDVRDQLAALVPPGFVTLTGLKRLPDLMRYLVAVDRRLQQMPTAVQRDTTRMAKVHEMQDEYAWLLEQLPRGRPVPQQVLDIRWMIEELRVSYFAHALGTAFPVSDKRIVKAIDAAAP
>CP032698.1|AYG81571.1|4154641_4154815_+|hypothetical-protein
MADTARHETRALLRAHLSAALGYRHLTRHCAVCHRLLRLAMEVAEPAGPEDERPPNR
>CP032698.1|AYG81572.1|4155215_4155422_-|hypothetical-protein
MTARTPDAEPLLTPAEVATMFRVDPKTVTRWAKAGKLTSIRTLGGHRRYREAEVRALLAGIPQQRSEA
>CP032698.1|AYG81573.1|4155918_4156761_-|hypothetical-protein
MAVVSSVIVPYASYLRVYEPLAAFAEPERGHWARYAERGRTPDAQDELRRALADLVPTPPVPVPVHESPDAFVAEIDGVVCVCPWRTRLRGWQALEGLAGQFPEPVLDALLPPVVRRQAEADYERWRERNPDARPWILTSVWHVPVSWFTVFSDEEREYAPGGGAEAPVLRYRTPMVQARRRLARALRTVRDRIDEGPLTEGLVDLGRWLEEFHPRSLVELDYGGLVHALSPQALVADRSAADVAEGIAALRAGDDAGAQEAYGRFTERWRAVKERRMAN
>CP032698.1|AYG81574.1|4156926_4158015_+|Valine-dehydrogenase
MTDVTGADDVLHTLFRSDQGGHEQVVLCQDRATGLRAVIAIHSTALGPALGGTRFYPYATEAEAVADALNLSRGMSYKNAMAGLDHGGGKAVIIGDPETIKTEDLLLAYGRFVASLGGRYVTACDVGTYVADMDVVARSCQWTTGRSPENGGAGDSSVLTAFGVFQGMRASAQHLWGDPTLRGRKVGVAGVGKVGRHLVEHLLSDGAEVVITDVREESVRAITDQHPEVAVAADTEALIRTEGLDIYAPCALGGALNDESVPVLTAKVVCGAANNQLAHPGVEKDLADRAILYAPDYVVNAGGVIQVADELHGFDFDRCKAKAAKIFDTTLAIFARAKEDGIPPAAAADRIAEQRMAEARQH
>CP032698.1|AYG81575.1|4158295_4158559_+|hypothetical-protein
MGRGRAKAKQTKVARQLKYSSGGTDLSRLANELGASTPNPTVSQPPNAEPLEDEEDDDPYARYAELYGSDDDDEDEESGSSAQRRGA
>CP032698.1|AYG81576.1|4158725_4159820_-|Phosphoribosylformylglycinamidine-cyclo-ligase
MSAEFDQRAPHAGTGASYAAAGVDIEAGDRAVELMKEWVKKTKRPEVLGGLGGFAGLFDASALKRYERPLLASATDGVGTKVDLARRMGVYDTIGHDLVGMVVDDLVVCGAEPLFMTDYICVGKVHPERVAAIVKGIAEGCVLAGCALVGGETAEHPGLLGPDDFDVAGAGTGVVEYDQLLGADRIREGDAVIAMASSGLHSNGYSLVRHVVFDRAGMTLESHVEEFGRTLGEELLEPTKIYSLDCLALTRTAEVHGFSHITGGGLANNLARVIPDHLHATVDRSTWTPGAVFDLVGRAGDVERLELEKTLNMGVGMMAIVPEVSVDVALQTLADRGVDAWVAGAVVERGEHREGAALTGDYAK

Crispr_ID: CP032698_41

• CRISPR_ID: CP032698_41
• CRISPR_location: 4174455-4174554
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_41

Consensus_repeat	Method
CCCTGGGGCTCCGCCCCAGACCCCG	CRISPRCasFinder

spacers of CP032698_41

>41.1|4174480|50|CP032698|CRISPRCasFinder
AGCCGCTTTGCCCACCCACCCGCCCGTGACGGGGGTTGGACAGCCCAGGC

CRISPR arrays and Neighbor proteins around CP032698_41

CRISPR arrays

The CRISPR arrays of CP032698_41

>merge|CP032698|41|4174455-4174554|CRISPRCasFinder
CCCTGGGGCTCCGCCCCAGACCCCGAGCCGCTTTGCCCACCCACCCGCCCGTGACGGGGGTTGGACAGCCCAGGCCCCTGGGGCTCCGCCCCAGACCCCG

>CP032698|41|32|4174455-4174554|CRISPRCasFinder
CCCTGGGGCTCCGCCCCAGACCCCG	AGCCGCTTTGCCCACCCACCCGCCCGTGACGGGGGTTGGACAGCCCAGGC
CCCTGGGGCTCCGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81589.1|4172733_4174236_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81590.1|4174942_4176592_-|hypothetical-protein	unknown	unknown	gnl|CDD|320687
CP032698.1|AYG81593.1|4181449_4182820_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81580.1|4163494_4165747_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl|CDD|234921
CP032698.1|AYG81583.1|4167050_4167368_+|Nucleoid-associated-protein-Lsr2	unknown	unknown	gnl|CDD|378714
CP032698.1|AYG81592.1|4178339_4180793_-|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl|CDD|236090
CP032698.1|AYG81596.1|4183811_4184333_-|Response-regulator-PleD	unknown	unknown	gnl|CDD|381085
CP032698.1|AYG81584.1|4167875_4168802_+|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	unknown	unknown	gnl|CDD|224054
CP032698.1|AYG81591.1|4177024_4178281_-|Phosphoribosylamine--glycine-ligase	unknown	unknown	gnl|CDD|234856
CP032698.1|AYG81594.1|4183113_4183329_+|hypothetical-protein	unknown	unknown	gnl|CDD|378324
CP032698.1|AYG81599.1|4186117_4188460_-|Germacradienol/geosmin-synthase	unknown	unknown	gnl|CDD|173835
CP032698.1|AYG81582.1|4166474_4166729_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl|CDD|235659
CP032698.1|AYG81581.1|4165743_4166478_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl|CDD|235140
CP032698.1|AYG81595.1|4183325_4183748_+|Ribonuclease-VapC21	unknown	unknown	gnl|CDD|350322
CP032698.1|AYG81598.1|4184860_4186054_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81587.1|4170848_4171460_+|Transcriptional-regulatory-protein-DesR	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG81588.1|4171691_4172591_-|Phosphoribosylaminoimidazole-succinocarboxamide-synthase	unknown	unknown	gnl|CDD|237571
CP032698.1|AYG81586.1|4169637_4170852_+|Sensor-histidine-kinase-DesK	unknown	unknown	gnl|CDD|226951
CP032698.1|AYG81597.1|4184481_4184781_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81585.1|4168798_4169617_+|hypothetical-protein	unknown	unknown	gnl|CDD|223912

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81594.1|4183113_4183329_+|hypothetical-protein	gnl|CDD|378324	pfam09957, VapB_antitoxin, Bacterial antitoxin of type II TA system, VapB. VapB is the antitoxin of a bacterial toxin-antitoxin gene pair. The cognate toxin is VapC, pfam05016. The family contains several related antitoxins from Cyanobacteria and Actinobacterial families. Antitoxins of this class carry an N-terminal ribbon-helix-helix domain, RHH, that is highly conserved across all type II bacterial antitoxins, which dimerizes with the RHH domain of a second VapB molecule. A hinge section follows the RHH, with an additional pair of flexible alpha helices at the C-terminus. This C-terminus is the Toxin-binding region of the dimer, and so is specific to the cognate toxin, whereas the RHH domain has the specific function of lying across the RNA-binding groove of the toxin dimer and inactivating the active-site - a more general function of all antitoxins.	8.84013e-06
CP032698.1|AYG81590.1|4174942_4176592_-|hypothetical-protein	gnl|CDD|320687	cd07328, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi.	0.000447489
CP032698.1|AYG81596.1|4183811_4184333_-|Response-regulator-PleD	gnl|CDD|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	7.80503e-24
CP032698.1|AYG81580.1|4163494_4165747_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl|CDD|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
CP032698.1|AYG81583.1|4167050_4167368_+|Nucleoid-associated-protein-Lsr2	gnl|CDD|378714	pfam11774, Lsr2, Lsr2. Lsr2 is a small, basic DNA-bridging protein present in Mycobacterium and related actinomycetes. It is a functional homolog of the H-NS-like proteins. H-NS proteins play a role in nucleoid organisation and also function as a pleiotropic regulator of gene expression.	1.9831e-48
CP032698.1|AYG81592.1|4178339_4180793_-|DNA-polymerase-III-subunit-gamma/tau	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0
CP032698.1|AYG81584.1|4167875_4168802_+|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	8.71561e-90
CP032698.1|AYG81591.1|4177024_4178281_-|Phosphoribosylamine--glycine-ligase	gnl|CDD|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
CP032698.1|AYG81582.1|4166474_4166729_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl|CDD|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	1.32874e-41
CP032698.1|AYG81581.1|4165743_4166478_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl|CDD|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	3.56918e-147
CP032698.1|AYG81595.1|4183325_4183748_+|Ribonuclease-VapC21	gnl|CDD|350322	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC3 and VapC21 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.05519e-53
CP032698.1|AYG81587.1|4170848_4171460_+|Transcriptional-regulatory-protein-DesR	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.94767e-58
CP032698.1|AYG81588.1|4171691_4172591_-|Phosphoribosylaminoimidazole-succinocarboxamide-synthase	gnl|CDD|237571	PRK13961, PRK13961, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	0
CP032698.1|AYG81586.1|4169637_4170852_+|Sensor-histidine-kinase-DesK	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	9.10253e-34
CP032698.1|AYG81599.1|4186117_4188460_-|Germacradienol/geosmin-synthase	gnl|CDD|173835	cd00687, Terpene_cyclase_nonplant_C1, Non-plant Terpene Cyclases, Class 1. This CD includes terpenoid cyclases such as pentalenene synthase and aristolochene synthase which, using an all-trans pathway, catalyze the ionization of farnesyl diphosphate, followed by the formation of a macrocyclic intermediate by bond formation between C1 with either C10 (aristolochene synthase) or C11 (pentalenene synthase), resulting in production of tricyclic hydrocarbon pentalenene or bicyclic hydrocarbon aristolochene. As with other enzymes with the 'terpenoid synthase fold', they have two conserved metal binding motifs, proposed to coordinate Mg2+ ion-bridged binding of the diphosphate moiety of FPP to the enzymes. Metal-triggered substrate ionization initiates catalysis, and the alpha-barrel active site serves as a template to channel and stabilize the conformations of reactive carbocation intermediates through a complex cyclization cascade. These enzymes function in the monomeric form and are found in fungi, bacteria and Dictyostelium.	7.49287e-89
CP032698.1|AYG81585.1|4168798_4169617_+|hypothetical-protein	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	4.74756e-12

Protein sequences

>CP032698.1|AYG81589.1|4172733_4174236_-|hypothetical-protein
MGVERSEHIRRWESGALAHAVSDPFGQGPLPWLRGSEHYFDDTGHVVPWYVDHVPAQRDTPRTTARTTAHVTGPRTADDVGQQIKGFASSGGVAPGEAIDFHITVDPPQQFTVDVYRIGHYGGDGAAKIATSPRLSGIVQPPPLTADRTVSCHHWWQSWRYQVPAHASIGAHVAVLTTADGYRSHIPFTVRDDHPADLLLLLPDITWQAYNLYPEDGRTGASLYHAWDEEGRLLGEEDAAITVSFDRPYAGAGLPLHVGHAYDFIRWAERYGYDLAYADARDLHAGRIDPTRYRGLVFPGHDEYWSAPMRRAVELARDGGTSLVFLSANSLYWQVELGPSPSGVPDRLLTCRKRRGPGRPALWREVARPEQQLLGIQYAGRVPEPHPLVVRNADHWLWEATGASDGEEIEGLVAGEADRYYPRTALPEHQDRILLAHSPYRDGEQNLRHQETSLYRAPSGALVFASGTFAWSPALDRPGHVDPRVQRATANLLDRICKRD
>CP032698.1|AYG81588.1|4171691_4172591_-|Phosphoribosylaminoimidazole-succinocarboxamide-synthase
MSGFVEKPEPLEVPGLTHLHTGKVRDLYQNEAGDLVMVASDRLSAYDWVLPTEIPDKGRVLTQLSLWWFDLLADLVPHHVISSEVPAGAPADWAGRTLVCKSLAMVPVECVARGYLAGSGLVEYNASRTVCGLALPEGLDNGSELPAPIFTPATKAAVGDHDENVSYEEVARQVGAETAALLRQTTLAVYGRARDIARERGIILADTKFEFGFAGEELVIADEVLTPDSSRFWPADSWEPGRDQPSYDKQYVRDWLTSPESGWDRTSEQPPPALPQHVVDATRAKYVEAYEQLTGVRWA
>CP032698.1|AYG81587.1|4170848_4171460_+|Transcriptional-regulatory-protein-DesR
MNRVRVLLADDEHLIRGALAALLGLEDDLEVVAEAASGPEALAMARAHRPDVAVLDLEMPGADGVTVATTLRTELPSCRTMIVTGHGRPGHLKRALSAGVRGFVPKTVSAQRLAEIIRTVHAGNRYVDPELAADAISAGDSPLTAREAEVLGFAADGAPVAEIAERAALSQGTVRNYLSSAAAKLGAGNRHTAVRLARERGWV
>CP032698.1|AYG81586.1|4169637_4170852_+|Sensor-histidine-kinase-DesK
MGRIRAWHQRHWRDRSRVEKVEVQSRLIWQCTTWFFFLSWEVPFVVQGLRHAPLPLALAVAALATGAAQAFQGIRSHRGALDQYLGRGDAPRGPLLVSCALCLTSLALVAALYAAHGLKLTDLVLIVLYVVMPFGMTYSTLTPPWPFLWRFALLALPTVAVFAAVGVRGGHLLALALVVALSGTYILLMARCGAWTLSVMWESDRARETEARLAVAEERLRFGRDMHDVLGRNLAVIALKAELAVQLAQRGRPEAVAQMVEVQRIAQESQKEVRDVVRGYREADLGVEIEGARGVLRAAGIGCRYAGPDDALTVEAQSALGWVVREATTNVLRHGDARSVAITLAVAEATATLVVENDGVPERPHGAPGSGLAGLRERLAALGGTLEAGPVGDGLFRLTAEVPR
>CP032698.1|AYG81585.1|4168798_4169617_+|hypothetical-protein
MSTTLDAVRGPARAKERALTSSADRMKALARAELTLLGRNKSALFTMFVLPTMLTCSMRPAVRGMDLEHAGLTVGTLLLPGALGYVLLFAVYSTLSAVYVVRREELVLKRLRTGELRDLEILAGAALPMVLIGLGQSLLLAVGCSVLMDVPVPGTVWLAAVGLLLGMGLMGALAAATAALTKSAEAAQVAVLPLMMLSILGSGMVVPLDVLPDRLASVCELLPLTPVIGLIRDGWTGGAGAGEVLRELLVMVVWTLIAVLVVRKRFRWEPRR
>CP032698.1|AYG81584.1|4167875_4168802_+|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA
MIEVEELRRTYAGGFEAVSGISFSVARGELFALLGTNGAGKTSTVELLEGLAPPSGGTVRVLGHDPYTERAAVRPRTGVMLQEGGFPAELTVAETVRMWAGCTSGARPVAEALELVDLARRSQVRVKQLSGGEKRRLDLALALLARPEVLFLDEPTTGLDAEGRRATWELVRALRDGGTTVLLTTHYLEEAEALAERLAILHEGRIAASGRVDEVVAAQPSHISFDLPDGYHLGDLPPLDRLGVVGHETAGRTVRLKTDKLQLAATGLLLWARDSDVELRGLDVRSASLEEAFLKIAQEQHGEAETVR
>CP032698.1|AYG81583.1|4167050_4167368_+|Nucleoid-associated-protein-Lsr2
MAQRVVVTLSDDIDGGEAAETVTFGLDGKVYEIDLNPANAKKLRKALAPYVTAGRKHTKSGRTYRHTAVAPDPAAVRAWARSNKMDVPARGRIPKKVYEAFAEAS
>CP032698.1|AYG81582.1|4166474_4166729_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurS
MARVVVDVMLKPEILDPQGQAVQRALPRLGFEGIGDVRQGKRFELEVDGPVDEAALARIHEMAETFLANTVIEDFTVKVEEQSK
>CP032698.1|AYG81581.1|4165743_4166478_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MTALPSPTAALPEGPSGLRNIRIGVVTFPGTLDDRDSLRAVRIAGAEPVSLWHRDKDLHQVDAIVLAGGFSYGDYLRAGAISRFSPVMETVIEQARAGMPVLGICNGFQILTESHLLPGAMLRNNHLHFICREQRLRVENAETAWTADYETGQEIRVPLKNMDGRYVADERTLDELEAEGRVAFRYLDGNPNGSLRDIAGITNAAGNVVGLMPHPEHAVEPLIGTGRTDGLGFFTSILKKLVNA
>CP032698.1|AYG81580.1|4163494_4165747_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurL
MTLDTVAHAAETPDVEQPWKELGLKEDEYARIREILGRRPTGAELAMYSVMWSEHCSYKSSKVHLAQFGEKAPENDAMLVGIGENAGVVDVGQGYAVTFKVESHNHPSYIEPYQGAATGIGGIVRDILAMGARPVAVVDPLRFGAADHPDTRRVLPGVVAGIGGYGNCLGLPNIGGEVVFDACYQGNPLVNAGCIGVMKHEDIHLAQASGPGNKVILYGARTGGDGIGGVSVLASETFESTGPAKRPAVQVGDPFQEKLLIECTLEIFKEKLVAGIQDLGGAGLSCATSELASAGSGGMRVELDTVPLRDSSLSPEEILMSESQERMCAVVEPQHVDRFLEICEKWDVIATVIGEVTEGSQLEIFWHGEQIVDVPPRTVAHEGPVYHRPFARPSWQDALQADDAGKLPRPQSGAELKDQVLKLVASPNQASKAWITDQYDRFVQGNTVLAMPEDAGMVRIDEESNLGVAMATDGNGRYAKLDPYTGAQLALAEAYRNVAASGAKPLAISDCLNFGSPEDPDVMWQFAEATRGLADGCLQLGTPVTGGNVSLYNQTGETAIHPTPVVAVLGVIDDVNRRTPIAFAEQGQLLYLLGDTREEFGGSAWSEVIHDHLGGLPPRVDLDREKLLGEILISGSRDGMIDAAHDLSDGGLIQAVTESCLKGGNGARLVVPDGLDAFTFLFSESAGRAVVSVPRSEELRFTDMCGARGLPATRIGVVDGEAIEVQGEFSLGLAELRTAHEATIPALLAH
>CP032698.1|AYG81590.1|4174942_4176592_-|hypothetical-protein
MGGEAGALHARSRALAVLRIRSRALAVALLPAAVAVVLIVAAAQGRIEGSAWHTARWSVTAAALLVLLLAAAVAAVIARARPALSPTVDLAESAAPDLYRLVRDLAERLDVPPPSAIALTPDCDSWLEDRTHPAHTAGRGALPARFIRRAGAGTARARRVSTAPVLVIGSPFMWWMRVGELRAILAPVVAGTGPSAHPDIAAARRFVRGLDAAVGVAARPGLDPVRRLALGFVGSIARLLLRGCRVHAAEMERGVAVAASERAQAVDYGVRIVAQEQVGLAYAGWDRLLTRVALPAWRMGRWPSRLDAGVVSALTELSRRDRLAEGFTTRLGERPACDLLEEPGIADEATSLLAARLFHGGPAEPGPDWAPVDWAAYPEEVVDRKWRTEAARLHRVLDALEEGGGAESAAPTLARVIDHLTASDGEAAERLSARIAAEVADEEAASAPLPPGPESWGDGVPLFPLQPPRTGRELLADHVTAMVCCAAVDTAGALPGLDWLDGPSLLVDEVRRSDLASPVLALVEDGDADGLRGWLAAVGVRPEKPLRLV
>CP032698.1|AYG81591.1|4177024_4178281_-|Phosphoribosylamine--glycine-ligase
MKVLVIGGGAREHALCRSLSLDPDVTALHCAPGNAGIAEVAELHPVDQLDGGAVARLAVELGSDLVVVGPEAPLVAGVADAVRAEGIPCFGPSREAALLEGSKAFAKDVMAAANVPTARSYVCTTPEEIDAALDAFGAPYVVKDDGLAAGKGVVVTDDLAAAREHALACDRVVIEEFLDGPEVSLFAITDGVTVLPLQPAQDFKRALDGDEGPNTGGMGAYSPLPWADPKLVDEVMESVLQPTVDELRRRGTPFSGLLYAGLAITSRGVRVIEFNARFGDPETQVVLARLRTPLAGVLFHSANGTLDVQPPLAWRDDAAVTVVIASHNYPATPRTGDPIEGLADVAAQDEPTAYVLHAGTRRDGDAVVSAGGRVLSVTATGEDLAQARERAYAAVGRIRLDGSQHRTDIAREAARTQG
>CP032698.1|AYG81592.1|4178339_4180793_-|DNA-polymerase-III-subunit-gamma/tau
MRPPVWRARAGRVGRRRGRLSVGPDNLVCVSSLALYRRYRPESFAEVIGQEHVTDPLQQALRNNRVNHAYLFSGPRGCGKTTSARILARCLNCEQGPTPTPCGECQSCRDLARNGPGSIDVIEIDAASHGGVDDARELREKAFFGPASSRYKIYIIDEAHMVTSAGFNALLKVVEEPPEHLKFIFATTEPEKVIGTIRSRTHHYPFRLVPPGTLREYLGEVCGQEGIPIEDGVLPLVVRAGAGSVRDSMSVMDQLLAGAADDGVTYAMATALLGYTDGSLLDSVVDAFAAGDGAAAFEVVDRVIEGGNDPRRFVADLLERLRDLVILAAVPDAGEKGLIDAPADVVERMQAQASVFGAAELSRAADLVNTGLTEMRGATSPRLQLELICARVLLPAAYDDERSLQARIDRLERGAHFQAAPVGGPAMGYMPGPEAHAPMQGGPGGPEAARAAVRGGGAGGAAPVAGPAHSGGAAPSGPPMQQPPAPQPPMPQPAQQAPAAPSRPVAPQPAPAQAAQPGQPAQSGQAFGQPAQQSPAGTWPSAASPGQGGGQRAGAWPGASAAAPTPAPAPTPTPSAGAWPSAASSAGSSATPAAAPEAAPAPAAQAPASGGAQGNAMQVRSMWPDILEAVKNKRRFTWILLSQNAQVAGFDGTTVQLGFINAGARDNFASSGSEDVLRSVLSERFGVQWKVEAIIDPSGGVQPPPAAGNFGGAAPRPPAPPVQQHQPHQQHQQHQAQASAQPPSSATSASPAPVPQVQQPPRGAAPVRHEEPPPPVRPEDDVPEDDDPDLVDNALSGHDLIVRELGATVVEEYTNEG
>CP032698.1|AYG81593.1|4181449_4182820_+|hypothetical-protein
MEAPIQRLRLVGACGRYPPHGTHAPEACQETRSAASVYTGATARALLSAQSTPRPRRDLTCDATRGPKHPGSLSQTERRLPNTGPAPSLAPSNILHSMGPNPSRIPPRHPCRSPRFPQTCPPYMMGKIMRDVFALISEAITRDFRGEPICAHVGDVRACTIKSHPPYKVLRKTVRLGRSRSVKSLRLWESVVTLAREGEPQEREKWLMILLDLLTLHFRGWSKELAQQWSYDLSDIRSAMVHGALEEWFSAPTGTPSNKLLDAMMARAFASARALVEAGRSETCAVSVEDLMADAAYEEGSTLRAASILDASTMLNPDSDERIRGERTGALLQSMGVMDHVKTFHAKLRSGCRDEVDASAISPEQLGRSWVDGRNLYYQFSDLLPTHLGFRKAADAAGLSESQASRKSNAGSLSFRVLWNGNSRVVPVKSLMRATGVHDSVVHPDDVENGASHVGG
>CP032698.1|AYG81594.1|4183113_4183329_+|hypothetical-protein
MSRTVIDLDDDLVAEVSKALGTSTKKETVNTALREVLDGRRRALALTRLRAASSEGAFDLDLLEDKRNYRR
>CP032698.1|AYG81595.1|4183325_4183748_+|Ribonuclease-VapC21
MNAAQFLIDTSALARFMRGDSDQYGWDQAAAAGLIATCPITELEFFYSARSAADRARGIEDMRLIFGWVPVDDRAYDRAWRVQEALTKQGKHRSAGAVDLVVAATAELQGLTLLHRDHDFECIAAVTGQALQWYGPEHGK
>CP032698.1|AYG81596.1|4183811_4184333_-|Response-regulator-PleD
MSADMKVLLVDDHEDNLFAMESILAPLGYPLELATSGDAALKAALHGGIGVAVLDVVMPGVSGLDVARYLSRLTQTRLIPVILVTGRGHDNEIAAQALHLGVADYLIKPIDPWALRIKVQYLYRTSTLLTGPAPRQRGPRTHPAEPTPLPTRRRQLRPTETIRIPHQPEDPPR
>CP032698.1|AYG81597.1|4184481_4184781_+|hypothetical-protein
MVFGWLVWTEFSHRAPRNIRGPTRPLAPASAADRMALSADTQVPLAHVSSPLTPTGEPAQVGPVIPAGPGRVDDTCKIGPVGPDRVVPRGLNDLAPYAR
>CP032698.1|AYG81598.1|4184860_4186054_+|hypothetical-protein
MNTAPATVRDRSAVLVPAVIGVVLMLAAGWLLLATAPHALDEERAFASASNCPVAEVSTECRHTITATVTSAAADHKHRSTYYWLGLGDVQEGSGALPGRLKASPAKVPAGGATPPHRVKMDGRAPVFAAVRPGATLHLTYWRGEIRYVEFRSLRQYTTADPRGGYRLPLAGALVSLSVGVACLRAAYCSARRATESPVHEPWRLTLPLGSVLLIVCFAFGTPWVTGGVPTALLLTAVGAVPVLSGAAWLTHRHRRRTPDTIKVTPLVPLVEECFPGAILGEVPYCHEGFRYVVAAPGLLAATPDPSGRIARQPVPRTLTAVRVRPPYWTDPGPRAAPDCQVVECRDGVTPVYVVTEQRYVPWVLGALQRSTDTRLRASDAERAERAEGAGRAERRG
>CP032698.1|AYG81599.1|4186117_4188460_-|Germacradienol/geosmin-synthase
MSQPFVLPDFYLPYPARLNPHLDSAREHSRVWAREMGMLEGSGIWELKDLDAHDYALLCSYTHPDCDADQLALVTDWYVWVFFFDDHFLEMFKRTLDRKGGKEYLDRLPAFMPMDLADGFPEATNPVEAGLADLWARTVPSMTREWRDRFATSTRNLLNESLWELSNINEGRVANPVEYIEMRRKVGGAPWSAGLIEYAANAELPASIAESRPARVLTDAFADAVHLRNDLFSYQREVEDEGELSNGVLVLENFLGCTTQEAAEAVNDLLTSRLQQFENTALTEMPRLCVEKGLTPDQCAAVGAYVKGLQDWQSGGHEWHMRSSRYMNEGAALSASPFDGALGTSARHGSTLFGRPAEARRRSFTHVPMQRVGPSLLPDFDMPYPLALSPHVGAARVASVDWADRMGLLDDIWDAEKLAGYDFALCAAGLDPDATPEELELSTEWLTWGTYGDDYYPLAFGRPRNLAAARAATDRLSACMPLDEPSAGHAAARTPMERGLADLWARTAGPMTGEARAAFRRAVDIMLESWLWELHNQAQHRIPDPVDYIEMRRYTFGADLTMSLARLRHAGQLPPGVRESGPLRSLENAAADYCTLLNDVFSYQKEIEYEGEVHNGVLVVQNFFNCDYPTALRIVDDLMRSRLRQFQHVITHELPVLCEDFELDEGERHVLGAHVAELQDWIAGILNWHESTRRYGAADLPDALPHGSSPHSVARGSVAPWWMRPTGAGTSADRVRLPEMLVSVAETVAPPVMATAAHSVPAGPPPPALPLSTVAQGHTV

Crispr_ID: CP032698_42

• CRISPR_ID: CP032698_42
• CRISPR_location: 4174624-4174811
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP032698_42

Consensus_repeat	Method
AGGGGCGCGGGGAACTGCGC	CRT
AGGGGCGCGGGGAACTGCGC	PILER-CR

spacers of CP032698_42

>42.1|4174644|38|CP032698|CRT
GACCAGCCACCTGCGGCCCGCAGACGAAAACGGTTTTT
>42.2|4174702|34|CP032698|CRT
AACCTGCCCCGTCCGGGGCCGCACCGGTTCTGCC
>42.3|4174756|36|CP032698|CRT
GAGAAGCGACCACGACCCGCAGATTCGAGAGGGTTT
>42.4|4174703|34|CP032698|PILER-CR
AACCTGCCCCGTCCGGGGCCGCACCGGTTCTGCC
>42.5|4174757|36|CP032698|PILER-CR
GAGAAGCGACCACGACCCGCAGATTCGAGAGGGTTT

CRISPR arrays and Neighbor proteins around CP032698_42

CRISPR arrays

The CRISPR arrays of CP032698_42

>merge|CP032698|42|4174624-4174811|CRT,PILER-CR
AGGGGCGCGGGGAACTGCGCGACCAGCCACCTGCGGCCCGCAGACGAAAACGGTTTTTGGGGGCGCGGGGAACTGCGCAACCTGCCCCGTCCGGGGCCGCACCGGTTCTGCCAGGGGCGCGGGGAACTGCGCGAGAAGCGACCACGACCCGCAGATTCGAGAGGGTTTAGGGGCGCGGGGAACTGCGC

>CP032698|42|4|4174624-4174811|CRT
AGGGGCGCGGGGAACTGCGC	GACCAGCCACCTGCGGCCCGCAGACGAAAACGGTTTTT
GGGGGCGCGGGGAACTGCGC	AACCTGCCCCGTCCGGGGCCGCACCGGTTCTGCC
AGGGGCGCGGGGAACTGCGC	GAGAAGCGACCACGACCCGCAGATTCGAGAGGGTTT
AGGGGCGCGGGGAACTGCGC

>CP032698|42|12|4174683-4174811|PILER-CR
GGGGCGCGGGGAACTGCGCA	ACCTGCCCCGTCCGGGGCCGCACCGGTTCTGCCA
GGGGCGCGGGGAACTGCGCG	AGAAGCGACCACGACCCGCAGATTCGAGAGGGTTTA
GGGGCGCGGGGAACTGCGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81589.1|4172733_4174236_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81590.1|4174942_4176592_-|hypothetical-protein	unknown	unknown	gnl|CDD|320687
CP032698.1|AYG81593.1|4181449_4182820_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81580.1|4163494_4165747_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurL	unknown	unknown	gnl|CDD|234921
CP032698.1|AYG81583.1|4167050_4167368_+|Nucleoid-associated-protein-Lsr2	unknown	unknown	gnl|CDD|378714
CP032698.1|AYG81592.1|4178339_4180793_-|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl|CDD|236090
CP032698.1|AYG81596.1|4183811_4184333_-|Response-regulator-PleD	unknown	unknown	gnl|CDD|381085
CP032698.1|AYG81584.1|4167875_4168802_+|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	unknown	unknown	gnl|CDD|224054
CP032698.1|AYG81591.1|4177024_4178281_-|Phosphoribosylamine--glycine-ligase	unknown	unknown	gnl|CDD|234856
CP032698.1|AYG81594.1|4183113_4183329_+|hypothetical-protein	unknown	unknown	gnl|CDD|378324
CP032698.1|AYG81599.1|4186117_4188460_-|Germacradienol/geosmin-synthase	unknown	unknown	gnl|CDD|173835
CP032698.1|AYG81582.1|4166474_4166729_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl|CDD|235659
CP032698.1|AYG81581.1|4165743_4166478_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl|CDD|235140
CP032698.1|AYG81595.1|4183325_4183748_+|Ribonuclease-VapC21	unknown	unknown	gnl|CDD|350322
CP032698.1|AYG81598.1|4184860_4186054_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81587.1|4170848_4171460_+|Transcriptional-regulatory-protein-DesR	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG81588.1|4171691_4172591_-|Phosphoribosylaminoimidazole-succinocarboxamide-synthase	unknown	unknown	gnl|CDD|237571
CP032698.1|AYG81586.1|4169637_4170852_+|Sensor-histidine-kinase-DesK	unknown	unknown	gnl|CDD|226951
CP032698.1|AYG81597.1|4184481_4184781_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81585.1|4168798_4169617_+|hypothetical-protein	unknown	unknown	gnl|CDD|223912

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81594.1|4183113_4183329_+|hypothetical-protein	gnl|CDD|378324	pfam09957, VapB_antitoxin, Bacterial antitoxin of type II TA system, VapB. VapB is the antitoxin of a bacterial toxin-antitoxin gene pair. The cognate toxin is VapC, pfam05016. The family contains several related antitoxins from Cyanobacteria and Actinobacterial families. Antitoxins of this class carry an N-terminal ribbon-helix-helix domain, RHH, that is highly conserved across all type II bacterial antitoxins, which dimerizes with the RHH domain of a second VapB molecule. A hinge section follows the RHH, with an additional pair of flexible alpha helices at the C-terminus. This C-terminus is the Toxin-binding region of the dimer, and so is specific to the cognate toxin, whereas the RHH domain has the specific function of lying across the RNA-binding groove of the toxin dimer and inactivating the active-site - a more general function of all antitoxins.	8.84013e-06
CP032698.1|AYG81590.1|4174942_4176592_-|hypothetical-protein	gnl|CDD|320687	cd07328, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi.	0.000447489
CP032698.1|AYG81596.1|4183811_4184333_-|Response-regulator-PleD	gnl|CDD|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	7.80503e-24
CP032698.1|AYG81580.1|4163494_4165747_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurL	gnl|CDD|234921	PRK01213, PRK01213, phosphoribosylformylglycinamidine synthase subunit PurL.	0
CP032698.1|AYG81583.1|4167050_4167368_+|Nucleoid-associated-protein-Lsr2	gnl|CDD|378714	pfam11774, Lsr2, Lsr2. Lsr2 is a small, basic DNA-bridging protein present in Mycobacterium and related actinomycetes. It is a functional homolog of the H-NS-like proteins. H-NS proteins play a role in nucleoid organisation and also function as a pleiotropic regulator of gene expression.	1.9831e-48
CP032698.1|AYG81592.1|4178339_4180793_-|DNA-polymerase-III-subunit-gamma/tau	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0
CP032698.1|AYG81584.1|4167875_4168802_+|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	8.71561e-90
CP032698.1|AYG81591.1|4177024_4178281_-|Phosphoribosylamine--glycine-ligase	gnl|CDD|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
CP032698.1|AYG81582.1|4166474_4166729_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl|CDD|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	1.32874e-41
CP032698.1|AYG81581.1|4165743_4166478_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl|CDD|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	3.56918e-147
CP032698.1|AYG81595.1|4183325_4183748_+|Ribonuclease-VapC21	gnl|CDD|350322	cd18755, PIN_MtVapC3_VapC21-like, VapC-like PIN domain of Mycobacterium tuberculosis VapC3, VapC21 and related proteins. This subfamily includes the Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of Mycobacterium tuberculosis VapC3 and VapC21 toxins. It belongs to the VapC-like family of the PIN domain nuclease superfamily. VapC is a PIN-domain ribonuclease toxin from prokaryotic VapBC toxin-antitoxin (TA) systems. VapB is a transcription factor-like protein antitoxin acting as an inhibitor. Other members of the VapC-like nuclease family include FitB toxin of the FitAB TA system, eukaryotic ribonucleases such as Smg6, ribosome assembly factor NOB1, exosome subunit Rrp44 endoribonuclease and rRNA-processing protein Fcf1. The structural properties of the PIN domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions; in some members, additional metal coordinating residues can be found while some others lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	1.05519e-53
CP032698.1|AYG81587.1|4170848_4171460_+|Transcriptional-regulatory-protein-DesR	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.94767e-58
CP032698.1|AYG81588.1|4171691_4172591_-|Phosphoribosylaminoimidazole-succinocarboxamide-synthase	gnl|CDD|237571	PRK13961, PRK13961, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	0
CP032698.1|AYG81586.1|4169637_4170852_+|Sensor-histidine-kinase-DesK	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	9.10253e-34
CP032698.1|AYG81599.1|4186117_4188460_-|Germacradienol/geosmin-synthase	gnl|CDD|173835	cd00687, Terpene_cyclase_nonplant_C1, Non-plant Terpene Cyclases, Class 1. This CD includes terpenoid cyclases such as pentalenene synthase and aristolochene synthase which, using an all-trans pathway, catalyze the ionization of farnesyl diphosphate, followed by the formation of a macrocyclic intermediate by bond formation between C1 with either C10 (aristolochene synthase) or C11 (pentalenene synthase), resulting in production of tricyclic hydrocarbon pentalenene or bicyclic hydrocarbon aristolochene. As with other enzymes with the 'terpenoid synthase fold', they have two conserved metal binding motifs, proposed to coordinate Mg2+ ion-bridged binding of the diphosphate moiety of FPP to the enzymes. Metal-triggered substrate ionization initiates catalysis, and the alpha-barrel active site serves as a template to channel and stabilize the conformations of reactive carbocation intermediates through a complex cyclization cascade. These enzymes function in the monomeric form and are found in fungi, bacteria and Dictyostelium.	7.49287e-89
CP032698.1|AYG81585.1|4168798_4169617_+|hypothetical-protein	gnl|CDD|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	4.74756e-12

Protein sequences

>CP032698.1|AYG81589.1|4172733_4174236_-|hypothetical-protein
MGVERSEHIRRWESGALAHAVSDPFGQGPLPWLRGSEHYFDDTGHVVPWYVDHVPAQRDTPRTTARTTAHVTGPRTADDVGQQIKGFASSGGVAPGEAIDFHITVDPPQQFTVDVYRIGHYGGDGAAKIATSPRLSGIVQPPPLTADRTVSCHHWWQSWRYQVPAHASIGAHVAVLTTADGYRSHIPFTVRDDHPADLLLLLPDITWQAYNLYPEDGRTGASLYHAWDEEGRLLGEEDAAITVSFDRPYAGAGLPLHVGHAYDFIRWAERYGYDLAYADARDLHAGRIDPTRYRGLVFPGHDEYWSAPMRRAVELARDGGTSLVFLSANSLYWQVELGPSPSGVPDRLLTCRKRRGPGRPALWREVARPEQQLLGIQYAGRVPEPHPLVVRNADHWLWEATGASDGEEIEGLVAGEADRYYPRTALPEHQDRILLAHSPYRDGEQNLRHQETSLYRAPSGALVFASGTFAWSPALDRPGHVDPRVQRATANLLDRICKRD
>CP032698.1|AYG81588.1|4171691_4172591_-|Phosphoribosylaminoimidazole-succinocarboxamide-synthase
MSGFVEKPEPLEVPGLTHLHTGKVRDLYQNEAGDLVMVASDRLSAYDWVLPTEIPDKGRVLTQLSLWWFDLLADLVPHHVISSEVPAGAPADWAGRTLVCKSLAMVPVECVARGYLAGSGLVEYNASRTVCGLALPEGLDNGSELPAPIFTPATKAAVGDHDENVSYEEVARQVGAETAALLRQTTLAVYGRARDIARERGIILADTKFEFGFAGEELVIADEVLTPDSSRFWPADSWEPGRDQPSYDKQYVRDWLTSPESGWDRTSEQPPPALPQHVVDATRAKYVEAYEQLTGVRWA
>CP032698.1|AYG81587.1|4170848_4171460_+|Transcriptional-regulatory-protein-DesR
MNRVRVLLADDEHLIRGALAALLGLEDDLEVVAEAASGPEALAMARAHRPDVAVLDLEMPGADGVTVATTLRTELPSCRTMIVTGHGRPGHLKRALSAGVRGFVPKTVSAQRLAEIIRTVHAGNRYVDPELAADAISAGDSPLTAREAEVLGFAADGAPVAEIAERAALSQGTVRNYLSSAAAKLGAGNRHTAVRLARERGWV
>CP032698.1|AYG81586.1|4169637_4170852_+|Sensor-histidine-kinase-DesK
MGRIRAWHQRHWRDRSRVEKVEVQSRLIWQCTTWFFFLSWEVPFVVQGLRHAPLPLALAVAALATGAAQAFQGIRSHRGALDQYLGRGDAPRGPLLVSCALCLTSLALVAALYAAHGLKLTDLVLIVLYVVMPFGMTYSTLTPPWPFLWRFALLALPTVAVFAAVGVRGGHLLALALVVALSGTYILLMARCGAWTLSVMWESDRARETEARLAVAEERLRFGRDMHDVLGRNLAVIALKAELAVQLAQRGRPEAVAQMVEVQRIAQESQKEVRDVVRGYREADLGVEIEGARGVLRAAGIGCRYAGPDDALTVEAQSALGWVVREATTNVLRHGDARSVAITLAVAEATATLVVENDGVPERPHGAPGSGLAGLRERLAALGGTLEAGPVGDGLFRLTAEVPR
>CP032698.1|AYG81585.1|4168798_4169617_+|hypothetical-protein
MSTTLDAVRGPARAKERALTSSADRMKALARAELTLLGRNKSALFTMFVLPTMLTCSMRPAVRGMDLEHAGLTVGTLLLPGALGYVLLFAVYSTLSAVYVVRREELVLKRLRTGELRDLEILAGAALPMVLIGLGQSLLLAVGCSVLMDVPVPGTVWLAAVGLLLGMGLMGALAAATAALTKSAEAAQVAVLPLMMLSILGSGMVVPLDVLPDRLASVCELLPLTPVIGLIRDGWTGGAGAGEVLRELLVMVVWTLIAVLVVRKRFRWEPRR
>CP032698.1|AYG81584.1|4167875_4168802_+|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA
MIEVEELRRTYAGGFEAVSGISFSVARGELFALLGTNGAGKTSTVELLEGLAPPSGGTVRVLGHDPYTERAAVRPRTGVMLQEGGFPAELTVAETVRMWAGCTSGARPVAEALELVDLARRSQVRVKQLSGGEKRRLDLALALLARPEVLFLDEPTTGLDAEGRRATWELVRALRDGGTTVLLTTHYLEEAEALAERLAILHEGRIAASGRVDEVVAAQPSHISFDLPDGYHLGDLPPLDRLGVVGHETAGRTVRLKTDKLQLAATGLLLWARDSDVELRGLDVRSASLEEAFLKIAQEQHGEAETVR
>CP032698.1|AYG81583.1|4167050_4167368_+|Nucleoid-associated-protein-Lsr2
MAQRVVVTLSDDIDGGEAAETVTFGLDGKVYEIDLNPANAKKLRKALAPYVTAGRKHTKSGRTYRHTAVAPDPAAVRAWARSNKMDVPARGRIPKKVYEAFAEAS
>CP032698.1|AYG81582.1|4166474_4166729_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurS
MARVVVDVMLKPEILDPQGQAVQRALPRLGFEGIGDVRQGKRFELEVDGPVDEAALARIHEMAETFLANTVIEDFTVKVEEQSK
>CP032698.1|AYG81581.1|4165743_4166478_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MTALPSPTAALPEGPSGLRNIRIGVVTFPGTLDDRDSLRAVRIAGAEPVSLWHRDKDLHQVDAIVLAGGFSYGDYLRAGAISRFSPVMETVIEQARAGMPVLGICNGFQILTESHLLPGAMLRNNHLHFICREQRLRVENAETAWTADYETGQEIRVPLKNMDGRYVADERTLDELEAEGRVAFRYLDGNPNGSLRDIAGITNAAGNVVGLMPHPEHAVEPLIGTGRTDGLGFFTSILKKLVNA
>CP032698.1|AYG81580.1|4163494_4165747_-|Phosphoribosylformylglycinamidine-synthase-subunit-PurL
MTLDTVAHAAETPDVEQPWKELGLKEDEYARIREILGRRPTGAELAMYSVMWSEHCSYKSSKVHLAQFGEKAPENDAMLVGIGENAGVVDVGQGYAVTFKVESHNHPSYIEPYQGAATGIGGIVRDILAMGARPVAVVDPLRFGAADHPDTRRVLPGVVAGIGGYGNCLGLPNIGGEVVFDACYQGNPLVNAGCIGVMKHEDIHLAQASGPGNKVILYGARTGGDGIGGVSVLASETFESTGPAKRPAVQVGDPFQEKLLIECTLEIFKEKLVAGIQDLGGAGLSCATSELASAGSGGMRVELDTVPLRDSSLSPEEILMSESQERMCAVVEPQHVDRFLEICEKWDVIATVIGEVTEGSQLEIFWHGEQIVDVPPRTVAHEGPVYHRPFARPSWQDALQADDAGKLPRPQSGAELKDQVLKLVASPNQASKAWITDQYDRFVQGNTVLAMPEDAGMVRIDEESNLGVAMATDGNGRYAKLDPYTGAQLALAEAYRNVAASGAKPLAISDCLNFGSPEDPDVMWQFAEATRGLADGCLQLGTPVTGGNVSLYNQTGETAIHPTPVVAVLGVIDDVNRRTPIAFAEQGQLLYLLGDTREEFGGSAWSEVIHDHLGGLPPRVDLDREKLLGEILISGSRDGMIDAAHDLSDGGLIQAVTESCLKGGNGARLVVPDGLDAFTFLFSESAGRAVVSVPRSEELRFTDMCGARGLPATRIGVVDGEAIEVQGEFSLGLAELRTAHEATIPALLAH
>CP032698.1|AYG81590.1|4174942_4176592_-|hypothetical-protein
MGGEAGALHARSRALAVLRIRSRALAVALLPAAVAVVLIVAAAQGRIEGSAWHTARWSVTAAALLVLLLAAAVAAVIARARPALSPTVDLAESAAPDLYRLVRDLAERLDVPPPSAIALTPDCDSWLEDRTHPAHTAGRGALPARFIRRAGAGTARARRVSTAPVLVIGSPFMWWMRVGELRAILAPVVAGTGPSAHPDIAAARRFVRGLDAAVGVAARPGLDPVRRLALGFVGSIARLLLRGCRVHAAEMERGVAVAASERAQAVDYGVRIVAQEQVGLAYAGWDRLLTRVALPAWRMGRWPSRLDAGVVSALTELSRRDRLAEGFTTRLGERPACDLLEEPGIADEATSLLAARLFHGGPAEPGPDWAPVDWAAYPEEVVDRKWRTEAARLHRVLDALEEGGGAESAAPTLARVIDHLTASDGEAAERLSARIAAEVADEEAASAPLPPGPESWGDGVPLFPLQPPRTGRELLADHVTAMVCCAAVDTAGALPGLDWLDGPSLLVDEVRRSDLASPVLALVEDGDADGLRGWLAAVGVRPEKPLRLV
>CP032698.1|AYG81591.1|4177024_4178281_-|Phosphoribosylamine--glycine-ligase
MKVLVIGGGAREHALCRSLSLDPDVTALHCAPGNAGIAEVAELHPVDQLDGGAVARLAVELGSDLVVVGPEAPLVAGVADAVRAEGIPCFGPSREAALLEGSKAFAKDVMAAANVPTARSYVCTTPEEIDAALDAFGAPYVVKDDGLAAGKGVVVTDDLAAAREHALACDRVVIEEFLDGPEVSLFAITDGVTVLPLQPAQDFKRALDGDEGPNTGGMGAYSPLPWADPKLVDEVMESVLQPTVDELRRRGTPFSGLLYAGLAITSRGVRVIEFNARFGDPETQVVLARLRTPLAGVLFHSANGTLDVQPPLAWRDDAAVTVVIASHNYPATPRTGDPIEGLADVAAQDEPTAYVLHAGTRRDGDAVVSAGGRVLSVTATGEDLAQARERAYAAVGRIRLDGSQHRTDIAREAARTQG
>CP032698.1|AYG81592.1|4178339_4180793_-|DNA-polymerase-III-subunit-gamma/tau
MRPPVWRARAGRVGRRRGRLSVGPDNLVCVSSLALYRRYRPESFAEVIGQEHVTDPLQQALRNNRVNHAYLFSGPRGCGKTTSARILARCLNCEQGPTPTPCGECQSCRDLARNGPGSIDVIEIDAASHGGVDDARELREKAFFGPASSRYKIYIIDEAHMVTSAGFNALLKVVEEPPEHLKFIFATTEPEKVIGTIRSRTHHYPFRLVPPGTLREYLGEVCGQEGIPIEDGVLPLVVRAGAGSVRDSMSVMDQLLAGAADDGVTYAMATALLGYTDGSLLDSVVDAFAAGDGAAAFEVVDRVIEGGNDPRRFVADLLERLRDLVILAAVPDAGEKGLIDAPADVVERMQAQASVFGAAELSRAADLVNTGLTEMRGATSPRLQLELICARVLLPAAYDDERSLQARIDRLERGAHFQAAPVGGPAMGYMPGPEAHAPMQGGPGGPEAARAAVRGGGAGGAAPVAGPAHSGGAAPSGPPMQQPPAPQPPMPQPAQQAPAAPSRPVAPQPAPAQAAQPGQPAQSGQAFGQPAQQSPAGTWPSAASPGQGGGQRAGAWPGASAAAPTPAPAPTPTPSAGAWPSAASSAGSSATPAAAPEAAPAPAAQAPASGGAQGNAMQVRSMWPDILEAVKNKRRFTWILLSQNAQVAGFDGTTVQLGFINAGARDNFASSGSEDVLRSVLSERFGVQWKVEAIIDPSGGVQPPPAAGNFGGAAPRPPAPPVQQHQPHQQHQQHQAQASAQPPSSATSASPAPVPQVQQPPRGAAPVRHEEPPPPVRPEDDVPEDDDPDLVDNALSGHDLIVRELGATVVEEYTNEG
>CP032698.1|AYG81593.1|4181449_4182820_+|hypothetical-protein
MEAPIQRLRLVGACGRYPPHGTHAPEACQETRSAASVYTGATARALLSAQSTPRPRRDLTCDATRGPKHPGSLSQTERRLPNTGPAPSLAPSNILHSMGPNPSRIPPRHPCRSPRFPQTCPPYMMGKIMRDVFALISEAITRDFRGEPICAHVGDVRACTIKSHPPYKVLRKTVRLGRSRSVKSLRLWESVVTLAREGEPQEREKWLMILLDLLTLHFRGWSKELAQQWSYDLSDIRSAMVHGALEEWFSAPTGTPSNKLLDAMMARAFASARALVEAGRSETCAVSVEDLMADAAYEEGSTLRAASILDASTMLNPDSDERIRGERTGALLQSMGVMDHVKTFHAKLRSGCRDEVDASAISPEQLGRSWVDGRNLYYQFSDLLPTHLGFRKAADAAGLSESQASRKSNAGSLSFRVLWNGNSRVVPVKSLMRATGVHDSVVHPDDVENGASHVGG
>CP032698.1|AYG81594.1|4183113_4183329_+|hypothetical-protein
MSRTVIDLDDDLVAEVSKALGTSTKKETVNTALREVLDGRRRALALTRLRAASSEGAFDLDLLEDKRNYRR
>CP032698.1|AYG81595.1|4183325_4183748_+|Ribonuclease-VapC21
MNAAQFLIDTSALARFMRGDSDQYGWDQAAAAGLIATCPITELEFFYSARSAADRARGIEDMRLIFGWVPVDDRAYDRAWRVQEALTKQGKHRSAGAVDLVVAATAELQGLTLLHRDHDFECIAAVTGQALQWYGPEHGK
>CP032698.1|AYG81596.1|4183811_4184333_-|Response-regulator-PleD
MSADMKVLLVDDHEDNLFAMESILAPLGYPLELATSGDAALKAALHGGIGVAVLDVVMPGVSGLDVARYLSRLTQTRLIPVILVTGRGHDNEIAAQALHLGVADYLIKPIDPWALRIKVQYLYRTSTLLTGPAPRQRGPRTHPAEPTPLPTRRRQLRPTETIRIPHQPEDPPR
>CP032698.1|AYG81597.1|4184481_4184781_+|hypothetical-protein
MVFGWLVWTEFSHRAPRNIRGPTRPLAPASAADRMALSADTQVPLAHVSSPLTPTGEPAQVGPVIPAGPGRVDDTCKIGPVGPDRVVPRGLNDLAPYAR
>CP032698.1|AYG81598.1|4184860_4186054_+|hypothetical-protein
MNTAPATVRDRSAVLVPAVIGVVLMLAAGWLLLATAPHALDEERAFASASNCPVAEVSTECRHTITATVTSAAADHKHRSTYYWLGLGDVQEGSGALPGRLKASPAKVPAGGATPPHRVKMDGRAPVFAAVRPGATLHLTYWRGEIRYVEFRSLRQYTTADPRGGYRLPLAGALVSLSVGVACLRAAYCSARRATESPVHEPWRLTLPLGSVLLIVCFAFGTPWVTGGVPTALLLTAVGAVPVLSGAAWLTHRHRRRTPDTIKVTPLVPLVEECFPGAILGEVPYCHEGFRYVVAAPGLLAATPDPSGRIARQPVPRTLTAVRVRPPYWTDPGPRAAPDCQVVECRDGVTPVYVVTEQRYVPWVLGALQRSTDTRLRASDAERAERAEGAGRAERRG
>CP032698.1|AYG81599.1|4186117_4188460_-|Germacradienol/geosmin-synthase
MSQPFVLPDFYLPYPARLNPHLDSAREHSRVWAREMGMLEGSGIWELKDLDAHDYALLCSYTHPDCDADQLALVTDWYVWVFFFDDHFLEMFKRTLDRKGGKEYLDRLPAFMPMDLADGFPEATNPVEAGLADLWARTVPSMTREWRDRFATSTRNLLNESLWELSNINEGRVANPVEYIEMRRKVGGAPWSAGLIEYAANAELPASIAESRPARVLTDAFADAVHLRNDLFSYQREVEDEGELSNGVLVLENFLGCTTQEAAEAVNDLLTSRLQQFENTALTEMPRLCVEKGLTPDQCAAVGAYVKGLQDWQSGGHEWHMRSSRYMNEGAALSASPFDGALGTSARHGSTLFGRPAEARRRSFTHVPMQRVGPSLLPDFDMPYPLALSPHVGAARVASVDWADRMGLLDDIWDAEKLAGYDFALCAAGLDPDATPEELELSTEWLTWGTYGDDYYPLAFGRPRNLAAARAATDRLSACMPLDEPSAGHAAARTPMERGLADLWARTAGPMTGEARAAFRRAVDIMLESWLWELHNQAQHRIPDPVDYIEMRRYTFGADLTMSLARLRHAGQLPPGVRESGPLRSLENAAADYCTLLNDVFSYQKEIEYEGEVHNGVLVVQNFFNCDYPTALRIVDDLMRSRLRQFQHVITHELPVLCEDFELDEGERHVLGAHVAELQDWIAGILNWHESTRRYGAADLPDALPHGSSPHSVARGSVAPWWMRPTGAGTSADRVRLPEMLVSVAETVAPPVMATAAHSVPAGPPPPALPLSTVAQGHTV

Crispr_ID: CP032698_43

• CRISPR_ID: CP032698_43
• CRISPR_location: 4204755-4204855
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_43

Consensus_repeat	Method
CGGGGTCTGGGGCAGAGCCCCAGG	CRISPRCasFinder

spacers of CP032698_43

>43.1|4204779|53|CP032698|CRISPRCasFinder
AGGCCCGGGCCATCCAACCCTGCGCCTACGGGCGGGCGGGTGGGAAAACGCGT

CRISPR arrays and Neighbor proteins around CP032698_43

CRISPR arrays

The CRISPR arrays of CP032698_43

>merge|CP032698|43|4204755-4204855|CRISPRCasFinder
CGGGGTCTGGGGCAGAGCCCCAGGAGGCCCGGGCCATCCAACCCTGCGCCTACGGGCGGGCGGGTGGGAAAACGCGTCGGGGTCTGGGGCGGAGCCCCAGG

>CP032698|43|33|4204755-4204855|CRISPRCasFinder
CGGGGTCTGGGGCAGAGCCCCAGG	AGGCCCGGGCCATCCAACCCTGCGCCTACGGGCGGGCGGGTGGGAAAACGCGT
CGGGGTCTGGGGCGGAGCCCCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81625.1|4216059_4216188_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81611.1|4198085_4198937_+|RNA-polymerase-sigma-factor-SigF	unknown	unknown	gnl|CDD|274373
CP032698.1|AYG81618.1|4205734_4207249_-|Antiseptic-resistance-protein	unknown	unknown	gnl|CDD|184957
CP032698.1|AYG81607.1|4195091_4195565_+|tRNA-specific-adenosine-deaminase	unknown	unknown	gnl|CDD|223663
CP032698.1|AYG81614.1|4200461_4200968_+|Multiple-antibiotic-resistance-protein-MarR	unknown	unknown	gnl|CDD|224759
CP032698.1|AYG81610.1|4196935_4197817_+|RNA-polymerase-sigma-factor-SigF	unknown	unknown	gnl|CDD|274373
CP032698.1|AYG81617.1|4204879_4205665_-|Tetracycline-repressor-protein-class-G	unknown	unknown	gnl|CDD|367243
CP032698.1|AYG81608.1|4196149_4196311_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81612.1|4199643_4199880_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81623.1|4213577_4214402_-|hypothetical-protein	unknown	unknown	gnl|CDD|368185
CP032698.1|AYG81609.1|4196358_4196652_+|hypothetical-protein	unknown	unknown	gnl|CDD|369566
CP032698.1|AYG81626.1|4216238_4216448_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81624.1|4215007_4215586_-|hypothetical-protein	unknown	unknown	gnl|CDD|378524
CP032698.1|AYG81615.1|4201016_4203503_+|Multidrug-resistance-protein-3	unknown	unknown	gnl|CDD|129794
CP032698.1|AYG81622.1|4212715_4213456_-|putative-transcriptional-regulatory-protein-TcrX	unknown	unknown	gnl|CDD|223816
CP032698.1|AYG81619.1|4207356_4209513_-|hypothetical-protein	unknown	unknown	gnl|CDD|379080
CP032698.1|AYG81620.1|4209509_4211012_-|Bifunctional-apolipoprotein-N-acyltransferase/polyprenol-monophosphomannose-synthase	unknown	unknown	gnl|CDD|133031
CP032698.1|AYG81616.1|4203661_4204480_+|Protein-YceI	unknown	unknown	gnl|CDD|377274
CP032698.1|AYG81613.1|4199941_4200157_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81621.1|4211038_4212583_-|putative-sensor-histidine-kinase-TcrY	unknown	unknown	gnl|CDD|223715

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81611.1|4198085_4198937_+|RNA-polymerase-sigma-factor-SigF	gnl|CDD|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	8.23625e-125
CP032698.1|AYG81618.1|4205734_4207249_-|Antiseptic-resistance-protein	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	7.45781e-69
CP032698.1|AYG81607.1|4195091_4195565_+|tRNA-specific-adenosine-deaminase	gnl|CDD|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	1.58445e-63
CP032698.1|AYG81610.1|4196935_4197817_+|RNA-polymerase-sigma-factor-SigF	gnl|CDD|274373	TIGR02980, SigBFG, RNA polymerase sigma-70 factor, sigma-B/F/G subfamily. This group of similar sigma-70 factors includes clades found in Bacilli (including the sporulation factors SigF:TIGR02885 and SigG:TIGR02850 as well as SigB:TIGR02941), and the high GC gram positive bacteria (Actinobacteria) where a variable number of them are found depending on the lineage.	2.18715e-117
CP032698.1|AYG81614.1|4200461_4200968_+|Multiple-antibiotic-resistance-protein-MarR	gnl|CDD|224759	COG1846, MarR, Transcriptional regulators [Transcription].	6.50856e-15
CP032698.1|AYG81617.1|4204879_4205665_-|Tetracycline-repressor-protein-class-G	gnl|CDD|367243	pfam02909, TetR_C, Tetracyclin repressor, C-terminal all-alpha domain.	7.63977e-09
CP032698.1|AYG81624.1|4215007_4215586_-|hypothetical-protein	gnl|CDD|378524	pfam10977, DUF2797, Protein of unknown function (DUF2797). This family of proteins has no known function.	1.15021e-35
CP032698.1|AYG81609.1|4196358_4196652_+|hypothetical-protein	gnl|CDD|369566	pfam07876, Dabb, Stress responsive A/B Barrel Domain. The function of this family is unknown, but it is upregulated in response to salt stress in Populus balsamifera. It is also found at the C-terminus of an fructose 1,6-bisphosphate aldolase from Hydrogenophilus thermoluteolus. Arthrobacter nicotinovorans ORF106 is found in the pA01 plasmid, which encodes genes for molybdopterin uptake and degradation of plant alkaloid nicotine. The structure of one has been solved and the domain forms an a/b barrel dimer. Although there is a clear duplication within the domain it is not obviously detectable in the sequence.	4.51979e-17
CP032698.1|AYG81615.1|4201016_4203503_+|Multidrug-resistance-protein-3	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	4.89353e-60
CP032698.1|AYG81622.1|4212715_4213456_-|putative-transcriptional-regulatory-protein-TcrX	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.11628e-84
CP032698.1|AYG81619.1|4207356_4209513_-|hypothetical-protein	gnl|CDD|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	1.36962e-29
CP032698.1|AYG81620.1|4209509_4211012_-|Bifunctional-apolipoprotein-N-acyltransferase/polyprenol-monophosphomannose-synthase	gnl|CDD|133031	cd04188, DPG_synthase, DPG_synthase is involved in protein N-linked glycosylation. UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate.	1.19205e-75
CP032698.1|AYG81616.1|4203661_4204480_+|Protein-YceI	gnl|CDD|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	8.66729e-54
CP032698.1|AYG81623.1|4213577_4214402_-|hypothetical-protein	gnl|CDD|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	1.91802e-34
CP032698.1|AYG81621.1|4211038_4212583_-|putative-sensor-histidine-kinase-TcrY	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.82893e-62

Protein sequences

>CP032698.1|AYG81616.1|4203661_4204480_+|Protein-YceI
MGLRAQVRTRDGWALSHAVVTMTDMTGTQVLRAAAAEDGSVAADVALAPGPYTVIVTAVGYAPAASTALVTASGRASVGTVVLARQGGVELPPPGPWTIDPAHSSVGAVAQHLGISSVHGRFGEFGGRIEIAEDLEKSRVEAVIGAASIDTGNAMRDGHLKSPDFLDVERFPEITYRSTGLTPAGPDRWTVHGELALHGVLREVDLDLTYLGTGPDPWGGVRAAYRATAELRREDFAMNYNQVVRAGVSAIGTTLRVSLDIQTVQGEVLPAG
>CP032698.1|AYG81615.1|4201016_4203503_+|Multidrug-resistance-protein-3
MATTTPAGVRGGHAKHGGHAPSDGGAPMTHRQIMEALSGLLLGMFVAILSSTIVSNALPHIISDLGGGQSAYTWVVTASLLAMTATTPLWGKLSDLFSKKLLVQIALIIYVSGSIVAGLSQSSGMLIACRVVQGIGVGGLSALAQIIMAAMISPRERGRYSGYLGATFAVATVGGPLLGGLITDTDWLGWRWCFYVGVPFAVIALIVLQKTLKLPVVKRDVKVDWTGAFLISAAVSLLLVWVTFAGNKYDWISWQTYAMVGGSIVLGALFVLAESKASEPIIPLRLFRNRTITLASLASLFVGVAMFAGTVFFSQYFQLARGRTPTMSGVMTIPMIGGLFISSTVSGQIITKTGKWKAWLVSGGVLVTAGLGLLGTMRYDTPYWHLAIYMALMGLGIGMMMQNLVLCTQNQVSPADLGSASSVVVFFRSLGGAVGVSALGAVMANRVTHYVTDGLTALGPQGAAAAKSGGGSGAIPDLATLPAPIRTVIESAYGHGVGDVFLYAAPCALLAFLITLFIKEIPLRSHAVGAAAAAEKTPVAETPAPAAGVEAAPAAATLTAPVVDAAPAPAPAVDGIVVRGTVRAAEGAPVASAAVTLISLGGSQLGRAVAGPDGGYALAAPGAGSYVLIAAADGFQPQASTIVVGAEPLSYDILLSGTSGLVGAVKAAETGAPVEGAMVIVTDVRGDLLATGKSGATGEFTFGELVPGQVTVAVNADGFRPLALPVEIAGYGVTRVEAALQAGALVQGTIRGGADRRPLADARVTLLDAAGNVVANATTGEDGAYAFADLNSGEYTLIATGYPPVAGSLTVAGRGVDGHDVELAHPGE
>CP032698.1|AYG81614.1|4200461_4200968_+|Multiple-antibiotic-resistance-protein-MarR
MAAQSLYEELARQLSAIGAVKRGLARILPPECPGGSAAVLTLLERHGEMRISRLAELLAVDMSVTSRHVAHVAQRGWIERSADPADKRSRILRLTPAGQAMIDDLGTRTTEMFAHTLKDWSDDEVGQLNAMLARLRDSFGDCRAPHARALHTGEARAPETRPPTRTPA
>CP032698.1|AYG81613.1|4199941_4200157_-|hypothetical-protein
MAHNPHAPQGPEGYDPAGSTQMFRAFVDEGAPQGGRPATPAAAPAGPRVGLIVGVVAVIVVLAAVAWLALG
>CP032698.1|AYG81612.1|4199643_4199880_+|hypothetical-protein
MQFRNTGGTAVTSGSVMFATHIIGLLGVDWATITSRQDLPVPIPAGTVRSRTYAVCVDAWRVPLGMHVETRSVTASWG
>CP032698.1|AYG81611.1|4198085_4198937_+|RNA-polymerase-sigma-factor-SigF
MSVEQGSSKVLTLTKSVPAPTVHRHAANTAAIDTRTLSRSLFLRLATLDNDSPERTYVRDTLIELNLPLVRYAAARFRSRNEPMEDIVQVGTIGLIKAIDRFDCERGVEFPTFAMPTVVGEIKRFFRDTSWSVRVPRRLQELRLALTKASDELAQKLDRSPTVPELAVVLGVSEEDVVDGLAVGNAYTASSLDSPATEDDGGEGSLADRLGYEDTALEGVEYRESLKPLLAKLPPRERQIIMLRFFANMTQSQIGEEVGISQMHVSRLLTRTLAQLREGLISD
>CP032698.1|AYG81610.1|4196935_4197817_+|RNA-polymerase-sigma-factor-SigF
MTVPASTTPQVPPQNEPQDTPDVPAQDTAEGPRGPVRTSTRGADTRALTQVLFGQLKNLEPGTPEHDRVRGALIEANLPLVRYAAARFRSRNEPMEDVVQVGTIGLINAIDRFDPDRGVQFPTFAMPTVVGEIKRYFRDNVRTVHVPRRLHELWVQVNGATEDLTTLHGRSPTTGEIAERLRIGEDEVLACIEAGRSYHATSLEAAQEGDGLPGLLDRLGYEDPALAGVEHRDLVRHLLVQLPEREQRILMLRYYSNLTQSQISQELGVSQMHVSRLLARSFARLRSANRIEA
>CP032698.1|AYG81609.1|4196358_4196652_+|hypothetical-protein
MIRHLVLFKLNEGVRRDDERVVAGVKAFQELDGIVPEIEFWECAWNITDRPIAYDFAINSAVADADALKRYIEHPAHQAAAGQWREFATWVIADYPF
>CP032698.1|AYG81608.1|4196149_4196311_+|hypothetical-protein
MDIKKVLLYIAVVFVLYTIITSPVQAAGMVQTGFEGISSAAKGVGEFMTNLVR
>CP032698.1|AYG81607.1|4195091_4195565_+|tRNA-specific-adenosine-deaminase
MLHPHDPVRERWAEPMRSALAGAAQAESAGDVPVGAVVLAPDGTFLASGHNEREATGDPTAHAEVLAIRRAAHRTGQWRLTGCTLVVTLEPCVMCAGALVQARIERVVYGARDEKAGAAGSLWDLVRDQRLNHRPEVVAGVLEEECSAQLTAFFRQR
>CP032698.1|AYG81617.1|4204879_4205665_-|Tetracycline-repressor-protein-class-G
MVSAADRSKDAARTSVWLGSKAGHRVRRAEPAEGGPALDRDRITAEAVRLLDAEGAAKFSMRRLAGELGVTAMSLYWYVDTKDDLLELALDAVFAEVDLPDAADEAADWRDQLRAVAVGYRAAFVRHPWASALVGRYLNIGPHSMAFSRTAQRIMARTGLPPHGQMGGLAAVFQFVYGFGTIEGTFVKRCADAGLTQDEYFASAMGALVERPEYREQFADAAELMAARGGETVVDMRQRDFDFALSLLIAGIEALRPAGRA
>CP032698.1|AYG81618.1|4205734_4207249_-|Antiseptic-resistance-protein
MTATTAENSTTTPTGHPQRWLILGVVCVAQLTVLLDNTVLNVAIPSLTTSLGASTADIQWMINAYSLVQSGLLLTAGSASDRYGRKKMLAAGLALFGIGSLAAGLAQNSGQLIAARAGMGIGGALLMTTTLAVVVQIFDDASRIKAIGIWATVNSLGFAAGPLIGGVMLDHFWWGAIFLVNIPVAVLGLVAVITLVPESKNPQGERPDLLGALLSTIGMTGVVYAIISGPGHGWLSTHVLVSAGVGAVFLAAFVRWELSIEHPMLDMHFFRNQRFIGAVAGSILVAFGMGGSLFLLTQHLQFVLGYGPLEAGLRTAPLALSVVALNMTGVGAKLVTKVGTPRAIAIGMTANAAGLASIALLGAHSYGGTLLGLVVMGAGIALSMPAMANAIMSAIPPEKAGVGAGVNGTLGEFGNGLGVAVLGAVLNSRFAALAPVAAASLPAALGAARDDAERGRIADAFASGLETSQLVGAVAVLAGGLLAAVLLHRAERSAPAPAGAAPAA
>CP032698.1|AYG81619.1|4207356_4209513_-|hypothetical-protein
MTTTSSPQADPREGVAAARRRRGAPARLWRGRPDDPAWARPALLALLAATCVAYLMNLGASGYANSFYSAAVQAGSESWKAFFFGSLDAANAITVDKPPAALWPMALSVRLFGLGSWQILLPEVLMGVGTVAVLYAAVRRRFSAAAGLISGAVLALTPVAALMFRFNNPDALLAFLMTVTVYCVLRALEGARTKWLVWAGVAIGFAFLTKTLQAFLILPPLALLYAVCAPTSVRRRLGQLALATGVLVVSGGWWVAVVELWPKSSRPYIGGSQHNSFIELTFGYNGLGRLSGDETGSVGGGARPGGMELPAGMELPAGMRAGGRGGGGWGETGIGRMFNSEIGGQISWLLPAALLLLVAGLVITWKAGRTDTARAAFLAWGGALLTTAGVFSFMAGIFHQYYTVALAPFIAALVGMGVTVLWEERARIGAALTLGVTVAGTALWSYVLLGRTPDYLPWLRWAVLIGGLAAAVGLALTGRLNRRLAVGVAGLGFAVALAGPAAYTVSTLETGHTGSIVTAGPAGASGGPAGGGPGGGGPGGGGGRTRFGGAPGAGQNGTPGLPPTTPTTPNAPASPGQDGQGGRTARGGMGGLLDGAEVGADAEALLRKNADQYTWAAAAIGSQNAASYQLATAEPVMAIGGFNGSDPSPTLAQFKRYVADGKIHYFVSSGGGMMGGGGGGRGGQSGGSSISSWVESSFKKVTVGTATFYDLTSPVAAG
>CP032698.1|AYG81620.1|4209509_4211012_-|Bifunctional-apolipoprotein-N-acyltransferase/polyprenol-monophosphomannose-synthase
MRTDPSASAPGATGAPTAPHAADPAHPTPHPADPRHPTPHATDPAHPTPHPAPHTPPHPTKSPPQPTALPARQHLPVQAAGVPVLDVTVPVHNEERDLEPCVRRLHEHLARTFPYGFRITIADNASTDSTPLIAAALAGDLSEVRAFRLEEKGRGRALRTVWSASDAPVLAYMDVDLSTDLNALLPLVAPLISGHSDLAIGSRLARSSRVVRGAKREFISRTYNLILRGSLAARFSDAQCGFKAIRRDVAQRLLPMVEDSGWFFDTEMLVLAERAGLRIHEVPVDWVDDPASTVHIVSTAMDDLKGVWRVGRALAVGALPLDRLSRPFGDDPRDRQLPGVPGGLARQLVGFCVVGALSTLFYLALYALARTAMNPQLANATALLVSAVANTSANRRLTFGVRGRDRAVRHQAQGLAVFAIGLALTSGSLAALDAAHAHAAHSTEVAVLVAANLAATVLRFLLFRAWVFPDRANAPGGATSPAAVTPETASSHPHPKGDAR
>CP032698.1|AYG81621.1|4211038_4212583_-|putative-sensor-histidine-kinase-TcrY
MSAVALLAVVGAVIGTVTVLAMGANLQSQLDAQLRGALVPGRMVGHESPGSGPLAGDPGSGTGTGTGTGTGTNKGAGRIDFVVSRPGQPLHAVAAGAGADGRVAGAQAVRPERQGEARSAALTAAQTRALAAVPKDGRVHSVTIAGLGDYRAVWDRENDFVLGFPNAAVDSTVNTLVVVVICVTAAGLVAAGIAGAAIVGVALRPLRRVASTATRVSELPLHSGEVALHERVPAAEADARTEVGQVGAALNRMLDHVHEALSARQESETRVRQFVADASHELRTPLASIRGYAELTRRGREDVGPDTRHSLGRIESEAARMTGLVEDLLLLARLDAGRPLSYESTDLSALVVDAVGDAHAAGQGHTWRLQLPEEPVAVYGDAERLQQVLVNLLANARTHTPPGTTVTARVEVRGPDAVVAVEDTGPGIPSALLPRVFERFARGDASRSRTAGSTAGSTGLGLAIVQAVVAAHGGRVDVHSRPGRTVFTVHLPGAPGSAAPAPTSQAEHRSTTQV
>CP032698.1|AYG81622.1|4212715_4213456_-|putative-transcriptional-regulatory-protein-TcrX
MTVTSSPQGRTEMLRPDGSPVRVLVVDDEAPLSELLSMALRYEGWDVRSAGDGAGAVRDARAFRPDAVVLDIMLPDMDGLAVLGRLRRELPDVPVLFLTAKDSVEDRIAGLTAGGDDYVTKPFSLEEVVARLRGLIRRSGAAALRSESVLTVGDLTLDEDSHDVTRGGVNIHLTATEFELLRFLMRNPRRVLSKAQILDRVWSYDFGGQANVVELYISYLRRKIDAGRSPMIHTRRGAGYLIKPGE
>CP032698.1|AYG81623.1|4213577_4214402_-|hypothetical-protein
MPQRVLDKVWRYFDSAGELVGGVEWPITYRAEEAERVRLLREEFGVLAFTSMIYPHKPGMAAWLNGWSAGFAARTDGCLHTSTFFPEPGVAAYVQDALEAGTRVFKSHVQVGSYDPGDPLLDPVWGLLAEADVPVVMHCGSGPAPGKYTGPGPIGRVLARHPRLRLIVAHMGMPEYADFLDLAEAYGSVMLDTTMAFTDFSERLAPFPSGELGRLADLGDRVLFGSDFPNIPYPYIHQLEALERLGLGDAWLRAVCHDNAARLFGPAPGRPSGE
>CP032698.1|AYG81624.1|4215007_4215586_-|hypothetical-protein
MVKVGITAEERGSARLLEQGAVAFGWLGRGPLMAARRCEELLRAALAVPDRIPYAAKRAVRARLPGVAERAAEVAALHARAVALADWPESLQRLECQVVDHAREFGLDGLPAASAVVTELVDHGVVSGRLIAAAGPDLHLEVGGGRGVVVLDARLMSGWDLAAVRPGESEGVTVPVREVPKEGERGVQDLLF
>CP032698.1|AYG81625.1|4216059_4216188_+|hypothetical-protein
MSSPYINAPVRARMYATKQHKVIWIVATVHAATLDTDWKADQ
>CP032698.1|AYG81626.1|4216238_4216448_-|hypothetical-protein
MDEPRIRLYGSADEVTIAANAAGLRELAERLMALADPELRDGYHQHLDAGINLEEGSINLILERDDKVW

Crispr_ID: CP032698_45

• CRISPR_ID: CP032698_45
• CRISPR_location: 4439148-4439226
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_45

Consensus_repeat	Method
CTCGCGCAGTTCCCCGCGCCCCT	CRISPRCasFinder

spacers of CP032698_45

>45.1|4439171|33|CP032698|CRISPRCasFinder
AAACCCCCTCGATCCTGCGGACCGTGCCCGCTT

CRISPR arrays and Neighbor proteins around CP032698_45

CRISPR arrays

The CRISPR arrays of CP032698_45

>merge|CP032698|45|4439148-4439226|CRISPRCasFinder
CTCGCGCAGTTCCCCGCGCCCCTAAACCCCCTCGATCCTGCGGACCGTGCCCGCTTCTCGCGCAGTTCCCCGCGCCCCT

>CP032698|45|35|4439148-4439226|CRISPRCasFinder
CTCGCGCAGTTCCCCGCGCCCCT	AAACCCCCTCGATCCTGCGGACCGTGCCCGCTT
CTCGCGCAGTTCCCCGCGCCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81826.1|4433672_4433966_+|hypothetical-protein	unknown	unknown	gnl|CDD|377231
CP032698.1|AYG81827.1|4434009_4434471_+|hypothetical-protein	unknown	unknown	gnl|CDD|377787
CP032698.1|AYG81839.1|4445714_4447661_-|hypothetical-protein	unknown	unknown	gnl|CDD|274051
CP032698.1|AYG81841.1|4448111_4450037_-|Actin-cross-linking-toxin-VgrG1	unknown	unknown	gnl|CDD|226032
CP032698.1|AYG81828.1|4434638_4435616_+|Quercetin-2,3-dioxygenase	unknown	unknown	gnl|CDD|224655
CP032698.1|AYG81824.1|4432495_4432726_-|hypothetical-protein	unknown	unknown	gnl|CDD|240596
CP032698.1|AYG81837.1|4443855_4445145_-|hypothetical-protein	unknown	unknown	gnl|CDD|237057
CP032698.1|AYG81833.1|4441414_4441690_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81835.1|4442513_4443215_+|55.5-kDa-and-49.5-kDa-sporulation-proteins	unknown	unknown	unknown
CP032698.1|AYG81840.1|4447660_4448101_-|hypothetical-protein	unknown	unknown	gnl|CDD|377431
CP032698.1|AYG81836.1|4443285_4443534_-|hypothetical-protein	unknown	unknown	gnl|CDD|377461
CP032698.1|AYG81834.1|4441686_4441908_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81822.1|4428732_4430028_-|putative-M18-family-aminopeptidase-2	unknown	unknown	gnl|CDD|235073
CP032698.1|AYG81830.1|4436199_4436796_+|HTH-type-transcriptional-regulator-AcrR	unknown	unknown	gnl|CDD|182632
CP032698.1|AYG81823.1|4430550_4432380_-|3-methylmercaptopropionyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173842
CP032698.1|AYG81829.1|4435653_4436139_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81831.1|4436826_4439049_-|Phosphoserine-phosphatase-RsbU	unknown	unknown	gnl|CDD|369272
CP032698.1|AYG81825.1|4432840_4433716_+|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG81838.1|4445151_4445718_-|hypothetical-protein	unknown	unknown	gnl|CDD|274050
CP032698.1|AYG81832.1|4439400_4441167_+|Aspartate--tRNA-ligase	unknown	unknown	gnl|CDD|234775

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81836.1|4443285_4443534_-|hypothetical-protein	gnl|CDD|377461	pfam05119, Terminase_4, Phage terminase, small subunit.	4.44202e-08
CP032698.1|AYG81827.1|4434009_4434471_+|hypothetical-protein	gnl|CDD|377787	pfam07179, SseB, SseB protein N-terminal domain. This family consists of several SseB proteins which appear to be found exclusively in Enterobacteria. SseB is known to enhance serine-sensitivity in Escherichia coli and is part of the Salmonella pathogenicity island 2 (SPI-2) translocon. This entry contains the presumed N-terminal domain of SseB.	3.76005e-05
CP032698.1|AYG81841.1|4448111_4450037_-|Actin-cross-linking-toxin-VgrG1	gnl|CDD|226032	COG3501, VgrG, Uncharacterized protein conserved in bacteria [Function unknown].	1.4369e-21
CP032698.1|AYG81828.1|4434638_4435616_+|Quercetin-2,3-dioxygenase	gnl|CDD|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	6.37153e-68
CP032698.1|AYG81824.1|4432495_4432726_-|hypothetical-protein	gnl|CDD|240596	cd12935, LEM_like, LEM-like domain of lamina-associated polypeptide 2 (LAP2) and similar proteins. LAP2, also termed thymopoietin (TP), or thymopoietin-related peptide (TPRP), is composed of isoform alpha and isoforms beta/gamma and may be involved in chromatin organization and postmitotic reassembly. Some of the LAP2 isoforms are inner nuclear membrane proteins that can bind to nuclear lamins and chromatin, while others are nonmembrane nuclear polypeptides. All LAP2 isoforms contain an N-terminal lamina-associated polypeptide-Emerin-MAN1 (LEM)-domain that is connected to a highly divergent LEM-like domain by an unstructured linker. Both LEM and LEM-like domains share the same structural fold, mainly composed of two large parallel alpha helices. However, their biochemical nature of the solvent-accessible residues is completely different, which indicates the two domains may target different protein surfaces. The LEM domain is responsible for the interaction with the nonspecific DNA binding protein barrier-to-autointegration factor (BAF), and the LEM-like domain is involved in chromosome binding. The family also includes the yeast helix-extension-helix domain-containing proteins, Heh1p (formerly called Src1p) and Heh2p, and their uncharacterized homologs found mainly in fungi and several in bacteria. Heh1p and Heh2p are inner nuclear membrane proteins that might interact with nuclear pore complexes (NPCs). Heh1p is involved in mitosis. It functions at the interface between subtelomeric gene expression and transcription export (TREX)-dependent messenger RNA export through NPCs. The function of Heh2p remains ill-defined. Both Heh1p and Heh2p contain a LEM-like domain (also termed HeH domain), but lack a LEM domain.	0.00674622
CP032698.1|AYG81837.1|4443855_4445145_-|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	6.27957e-09
CP032698.1|AYG81826.1|4433672_4433966_+|hypothetical-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.09997e-21
CP032698.1|AYG81840.1|4447660_4448101_-|hypothetical-protein	gnl|CDD|377431	pfam04965, GPW_gp25, Gene 25-like lysozyme. This family includes the phage protein Gene 25 from T4 which is a structural component of the outer wedge of the baseplate that has acidic lysozyme activity. The family also includes relatives from bacteria that are also presumably lysozymes.	2.62986e-33
CP032698.1|AYG81839.1|4445714_4447661_-|hypothetical-protein	gnl|CDD|274051	TIGR02243, hypothetical_protein_SCD8A.17c, putative baseplate assembly protein. This family consists of a large, conserved hypothetical protein in phage tail-like regions of at least six bacterial genomes: Gloeobacter violaceus PCC 7421, Geobacter sulfurreducens PCA, Streptomyces coelicolor A3(2), Streptomyces avermitilis MA-4680, Mesorhizobium loti, and Myxococcus xanthus. The C-terminal region is identified by the broader model pfam04865 as related to baseplate protein J from phage P2, but that relationship is not observed directly. [Mobile and extrachromosomal element functions, Prophage functions].	3.15425e-159
CP032698.1|AYG81822.1|4428732_4430028_-|putative-M18-family-aminopeptidase-2	gnl|CDD|235073	PRK02813, PRK02813, putative aminopeptidase 2; Provisional.	0
CP032698.1|AYG81830.1|4436199_4436796_+|HTH-type-transcriptional-regulator-AcrR	gnl|CDD|182632	PRK10668, PRK10668, DNA-binding transcriptional repressor AcrR; Provisional.	2.82312e-08
CP032698.1|AYG81823.1|4430550_4432380_-|3-methylmercaptopropionyl-CoA-dehydrogenase	gnl|CDD|173842	cd01153, ACAD_fadE5, Putative acyl-CoA dehydrogenases similar to fadE5. Putative acyl-CoA dehydrogenase (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	0
CP032698.1|AYG81831.1|4436826_4439049_-|Phosphoserine-phosphatase-RsbU	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	7.44389e-51
CP032698.1|AYG81825.1|4432840_4433716_+|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.24937e-06
CP032698.1|AYG81838.1|4445151_4445718_-|hypothetical-protein	gnl|CDD|274050	TIGR02242, putative_secreted_protein, phage tail protein domain. This model describes a region of sequence similarity shared by a number of uncharacterized proteins in bacterial genomes, including Geobacter sulfurreducens PCA, Mesorhizobium loti, Streptomyces coelicolor A3(2), Gloeobacter violaceus PCC 7421, and Myxococcus xanthus. In all cases, the genomic region resembles a phage tail region, based on tentative identifications of neighboring genes. A region of this domain resembles a region of TIGR01634, another phage tail protein model. [Mobile and extrachromosomal element functions, Prophage functions].	9.3645e-36
CP032698.1|AYG81832.1|4439400_4441167_+|Aspartate--tRNA-ligase	gnl|CDD|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0

Protein sequences

>CP032698.1|AYG81831.1|4436826_4439049_-|Phosphoserine-phosphatase-RsbU
MRTEDVLAAIATGLWRWDNASGTVTLDAEAARLLGLPAQRVTLSEAAVRSRFHPVDWNEVDGIVHLALAEGTLAEVRLRIMDENGRVLRTVRSRSKPMLNGKSYLLIGTIQEVAEPQPGTTAAQPSITGDWRRSREAFLLDAGRALAEARSTSEVLRVAASLSMPGFSPDGLAVFGVAGERLTIIGHHGHNPGDDGPFTDMALDMDYPAADVVRNGRAIYLPSPQEYRRRFPATWPLAQRFDRQSWAFVPLIVAGRTIGAWMAAFKHPVAFTPDERSVLTTVARMLAQALARAGEAESERELSLGLQRSMMPTLGPEIPGMAVAARYVPTGGGLQVGGDWYDMIPLPGGGSRTDSGGGRFALVIGDVQGHDVRAAGLMGQLRIALRAYASEGHSPDAVLSRASRFLYGITESYGVPDPYGDGYEDYAPRFATCLYIEVDPATGTLDIARAGHPDPVIRTADGTALIRSTAGGLPLGIEADSDYPTTRLVLDPDETIMLCTDGLIETGGHDMASGWTRLRPVLEKHTDDNLEQLADELVQAVHGPSSHHTTGPLVDRREDDIALLLLRRNSLAGRPGAAPPAAVRRTALTVAQAEPEQIAGARRQLRELLHDWADEDQVDSAVLMISEMITNVLVHTDGDALLVAEARGPLGTRRLRVEVADASDELPHRRRPGELASSGRGLILMEMLADAWGVDPRGDGKSIWFELYETGGAGEADGGRGRGAREGAATDRGGQGPRAE
>CP032698.1|AYG81830.1|4436199_4436796_+|HTH-type-transcriptional-regulator-AcrR
MARRHLTPQDWSTAALRAMARGGVAAVSVNALAGELGATRGSFYWHFKDRDALLTAALEMWERKTTTALITELGDITDPRQRLRVLLTTGLGPGSSDGLEPAIVAHADHPAVARVLRRVTERRISYLTDLYADLGLAPAAARRQAVAAYATYLGWHELRHSVCDIVPEVATEGAVAGAALEHLITELARPAVHRAKPE
>CP032698.1|AYG81829.1|4435653_4436139_-|hypothetical-protein
MTVTKLADGEAEVGLGAAGGGRGRPRMTRWIPRLVTGLAALHFAVALSAASTFGDVARAGFWNAVPGNPQRGYETWFFIAGFGLLALGTLSQRIVRDTGILPAQLGWYLLAIGVPLQILCPVSGAPGLIVLGVLALIAARRGRAGESRTPVSPTAEREQGS
>CP032698.1|AYG81828.1|4434638_4435616_+|Quercetin-2,3-dioxygenase
MPAVTVENPLTLPRVTAPEGASARPVLAVTTAPQGFEGEGFPVRRAFAGINYKYLDPFIMMDQMGEVEYAPGEPKGTPWHPHRGFETVTYIIDGIFDHQDSNGGGGTITNGDTQWMTAGSGLLHIEAPPESLVVSGGLFHGLQLWVNLPARDKMMAPRYQDIRSGSVQLLTSPDGGALMRVIAGELDGHEGPGITHTPITMVHATLAPGAEITLPWRQEFNGLAYVLAGRGSVGAERRPVHAGQTAVFGEGGSLTVRADEKQDSHTPDLEVVLLGGQPIREPMAHYGPFVMNTRAELEQAFEDFQKGRLGTIPAVHGMTASGPQG
>CP032698.1|AYG81827.1|4434009_4434471_+|hypothetical-protein
MYGYDQNPGAQQQYAPPQQQMQGGYGEQPLYPEPSPPSLADAVRAFTTGSLSAEDFQQIFAGARVYCPRGDNPGFLALHNTQQPVIPMFTSLKELRRYAGKESKYFVITGAEVIDLLPTGYGFVLDMEGDHRMVFDAKAVEQMVDFAMRRMYG
>CP032698.1|AYG81826.1|4433672_4433966_+|hypothetical-protein
MVGAAPDLSAARWRKSSYSNGDGGDCVEVAEGFLGAARWRKSTYSNGDGGNCVEVADNLPGVVPVRDSKAPNGPALIIAAGAWVPFVEAVKAAGLRG
>CP032698.1|AYG81825.1|4432840_4433716_+|hypothetical-protein
MAVRKEIDGSASVPEFYGKELRWQRERAGLTLEQLVEGSFYGVSYLSEIERGQRRMPPDLARHVDQALKTDGFFARRCGDVRKARQGAHAAYFAPVAESETRALVIEEWANALIPGLLQTEAYARAVIHATHPLALPEEVDAKVHARRQRARIFDDPKCPEYWVVLHESLLGSPMLPSAEMAEQLDRIAALAHRRRIVPQILPWNDATRHFMTSSLKLMEFDHEPPIVYTEGMYHGQLIDDPALVRRYHKAYDRLRAAALPLEASLALLDQAAEEYRNGGRSTGLERGSLA
>CP032698.1|AYG81824.1|4432495_4432726_-|hypothetical-protein
MSKTPLTPRRDDTYNTVMELRAALAEHGITLPSLGRDFGTPPLVILGNCNADTARALTAALERHPEPHPAHQSSTA
>CP032698.1|AYG81823.1|4430550_4432380_-|3-methylmercaptopropionyl-CoA-dehydrogenase
MGHYKSNLRDIEFNLFEVLGRDKLYGTGPFGEMDVDTAKSILEEIARLAENELADSFADADRNPPVFDPATNTAPVPASFKSSYKAFMDSEYWRLGLPEEIGGTVSPRSLIWAYAELLLGSNPAIWMYSSGPAFAGILFEEGNEQQKKIAEIAVEKRWGSTMVLTEPDAGSDVGAGRTKAVQQDDGSWHIEGVKRFITSGEHDMEENILHYVLARPEGHGPGTKGLSLFLVPKFHFDWETGELGERNGVYATNVEHKMGLKASNTCEMTFGDQHPAKGWLIGDKHDGIRQMFMIIEFARMMVGTKAIATLSTGYLNALEYAKERVQGSDLSQFMDKTAPKVTITHHPDVRRSLMTQKAYAEGMRSLVLYTASIQDAIQVKEAAGEDAKALVGLNDLLLPIVKGYGSEKSYEKLSHESLQTFGGSGYLQEYPIEQYIRDAKIDTLYEGTTAIQGQDFFFRKIVRDQGASLNALSEEIKKFLAEQNGNEALGGSLDALAKAAVDLEAIVGTMITDLTATGEDVKNIYKVGLNTTRLLMASGDVVVGYLLLKGAAVAAEKLSSASAKDVPFYTGKIAAAKFFAANVLPEVGTARLLAESVDNSLMELDEAAF
>CP032698.1|AYG81822.1|4428732_4430028_-|putative-M18-family-aminopeptidase-2
MSTPPRFDRGHTDDLMTFLAASPSQYHAVANAAARLEKAGFRQVQETDAWDGTHGGKYVLRGGAIVAWYVPEGAAPHTPYRIVGAHTDSPNLRVKPQPDSGAYGWRQVAVEIYGGTLLNTWLDRDLGIAGRLTLKDGSHRLVNVDRPLLRVPQLAVHLDRSVNTDGLKLDRQRHLQPIWGLGDDVHEGDLIRFLEQEAELDEGDVAGWDLMLHSVEAPAYLGRDRELVAGPRMDNLLSVHAGAAALAAVSGDDDLPFIPVLAAFDHEEDGSQADTGADGPLLGNVMERSVFARGGTYEDRARAFAGTICLSSDTGHAVHPNYAERHDPTHHPRANGGPILKVNVNARYATDGAGRAVFAAACERAGVPWQTFVSNNAMPCGTTIGPITAARHGIQTVDIGVAILSMHSARELCGADDPHLLSGALAAFLSA
>CP032698.1|AYG81832.1|4439400_4441167_+|Aspartate--tRNA-ligase
MHRYRSHTCGELRASDVGADVRLSGWLHNRRDLGGILFIDLRDHYGITQLVARPGTAGAEALDKLSKETVVRVDGKVVSRGAENVNGELATGEIEIEVGEVEVLGAANPLPFTINADDGVNEERRLEYRFLDLRRERMHRNIMLRSAVIASIRSKMVALGFNEMATPILAATSPEGARDFVVPSRLNPGKFYALPQAPQQFKQLLMISGFDRYFQIAPCFRDEDARADRSPGEFYQLDVEMSFVEQEDVFQPIEKLMTEIFEEFGGGRQVTSPFPRIPFRESMLKYGNDKPDLRAKLELADITDVFEGSEFKAFAGKHVRALPVPDVASQSRKFFDGLGEYAVSLGAQGLAWVRVGEDGSLSGPIAKFLTEENVKVLTERLGLVPGHAVFFGAGEFDDVSKIMAGVRVEAAKRAGHFEEGVFRFCWIVDFPMYEKDEETGKIDFSHNPFSMPQGGLEALETQDPLDVLGWQYDIVCNGIELSSGAIRNHEPEIMFKAFEVAGYDRETVEREFGGMLKAFRLGAPPHGGIAPGVDRMVMLLADEPNIRETIAFPLNGNAQDLMMGAPTELDESRLRELNIALRKPVADK
>CP032698.1|AYG81833.1|4441414_4441690_-|hypothetical-protein
MRTPRAVIRPVKHSIGTHPRGEITVSALCLDGACLWTLATTSDLKAADLAMMTHTGLSGHPTFARTFEDVALVRRLKLHARPDPCPLDRKQ
>CP032698.1|AYG81834.1|4441686_4441908_-|hypothetical-protein
MADNWSPTMGSYAVDTADNRIGEARRLFRGSMYLVPPGGGAEWAAPPNRLRPPTDAEVWQARVWTRPVGSSWQ
>CP032698.1|AYG81835.1|4442513_4443215_+|55.5-kDa-and-49.5-kDa-sporulation-proteins
MGQIAGWIASDAGQHSEAEQFYRLGLSAARQAEDHTLAGNLAGSLAYQLSNTGREVEGIQLARAALDAAGTDAPAKARALYLDRVAWAHTKAGEFQPAIRALGEAGEALSQDRKGSEAPAYLYWVDSGELQVMEARVYTELRRPLRAVPLLRDVLSWYDATHTRELALYLSWLAVALSDANEPEEAVTVAERVMSLSADVASERTAERVRIVLARLEEFHDIPDVRALLDGAA
>CP032698.1|AYG81836.1|4443285_4443534_-|hypothetical-protein
MQGTEPGRRVCVARIDQAERDLSERGLIVTAERGTVKNGAATIAAQYRTQLARYICELSLSPSARTAITAPEPEGDDSGVWD
>CP032698.1|AYG81837.1|4443855_4445145_-|hypothetical-protein
MTTPAMVPCPDCGTPARATGQSFCDSCGAFLRWSAPAAPPANAPAPDAAADTAPEAVTTPIPAVANPAEGAGAGAGAADRAGAASTAAPAAPAGSAAGASAGDTTPLPEVTPGARPDARTEARPDVRPDVRPDAAANEPVTPHPETRAPSVSDAARALLVPVQEPTARAPEAPGTVLPGRPEAARPKVRAATPAPAPENGTPCPACGTANHQHRSFCRSCATPLTPRREDNATGPYAGQRPPLHRDRKRWIARALTAAAVVALVVGGVFGGPPAARAVQDHFAKRVAVHPATWTASHWDPKHGPELAGDSYSNTWWGTGYAGDAQGTYLEATFGQPTDLLALLITPGTSKRQGQQSEQARPQEFDLLVTDTSGKAHVSHRSLNDGGVQRIDVRVRDAASVRLTLRSAFGAAKDKQVAIAEVEFFARSKN
>CP032698.1|AYG81838.1|4445151_4445718_-|hypothetical-protein
MSTRGSVDGLASSHPLGAQLPAVYADDDLAQRFVEGLDVVLAPLFNVLDCLEAYFDPALAPEDFVDWLTGWVGTELDGTEPLEIRRHAVATAVSLHRVRGTAQGLSRAVHLAFGVRPEISESGGAAWSARPLGPFPGDPKPSLRVTLRLSDPSSVDPHRLQAVVAAARPAHLPFTAEVSAKTLTPEGN
>CP032698.1|AYG81839.1|4445714_4447661_-|hypothetical-protein
MALPAPHLDDRRFQQFVDDAKRYIQQRCPEWSDHNVSDPGVTLIEAVAHMADQVVYRLNRVPEKNQLAFLDLLGVTLFPPSAARASVTFWLSAPQAEPVVLPRGTEVATGRTETEEAVVFASENDLTIVPCTLTHVLRQPAGSAPEDCSQDVLGNTDVSVFSSGPLPGDVLLFGLSAALPHCTAVLRLESRVDGVGVDPRQPPLVWEAWTADGWSECEVAEDTTGGLNRPGEVVLHMPTTHAVSRMGRLEAGWLRCRVVEAAPGQPFYSVSPTVRGASAFTIGGTTRVSHSESVRDESLGESEGVPGQRLMLAHAPVVGGVRLEVSAGEGWEEWETVDDFASSSPFDRHFTLDAATGELAFGPSVRQPDGSVRQFGAVPLKGAAIRASQYGTGGGRSGNVARGAIQVLRSSIPYISRVENREAARGGVDGETVEEAKIRAPIALRAQERAVTARDYEELARRAAPETARIACLAADAAESGDNAVRVLVVPQAVPDRGGRLRFEQLVPGDELLGRVTSFLDDRRPLGTRLAVGPPFYQGVTVVATLHAFRAAKADHVRDDALNTLYSYLDPLTGGAHGTGWPFGRPLRAGEIFAALQRVPGVELVDEVLLHPADPLTGRRGDATDRIDLSSSALLFPFDHRVRVIEAR
>CP032698.1|AYG81840.1|4447660_4448101_-|hypothetical-protein
MSEHFVGAGWAFPMRTEPGGGIALARRDREIEESMRLVLATAPGERPMRPEFGCAVHDLVFAPVNDATAGRIRYEVRTSLDRWEPRIEVEDVTVTPAPDEPTVLHIDVRYSVRGTNNPRSLVFPFYVIPSEGGDEPGPTAGESERH
>CP032698.1|AYG81841.1|4448111_4450037_-|Actin-cross-linking-toxin-VgrG1
MTEKTFTTVLHVQLNGTVLPDPLALRLVEGWVDSSVNVPAAFQLTFSDKDSKLTTKFPMLKIGAKVIISPFTDGRRGDPMMTGEVTALEMDSEPGSGRHLLVRGYDPGHRLLRNRRVEGYPNMTASDIVRRIAGQNGLKIGKIESTSAVYDLATQPNITDWDFLSRLAAENDVRLSFDNQGKLNFAGLDPASGAPSDTTPAAQSPYVLDFGANNLHSRATMTAAGQVRKVNVRGWDMRTRQKLQAPVPAVTSKDISADMTPGQVTLPFGASELTATHVPYTTLSQVTHAAKALADDVTGAFAELEVAITGNPELKPGTPIAVKGAGFPFEGKYTATGVRHVFASGDLYTTWLTVSGRQFRSLYGLASGGTEQAPPMPGVAVALVTNTKDPLRMGRVRLSFPWLSATYESDWCRVAQFGGKGGGGLLLPEVNDEVLCAFDRGSLEHPYVIAGLYNGIDKHTREPDNYPAVDPTSGEINWRSLTGRSGHTLEILESGGAARMESGIRLRTGRGRLHIQMNEARTSLTIHSDGSVDIRGTRSVDIEAGGDLSLKAGGNLSLKSGGAIEIDAGMAINVKAGLAFDVKAGGEASIGAGGMLALNSIGATTINAIANLTIDSATILVNAPAFSIQSAAPLVNGAPII

Crispr_ID: CP032698_46

• CRISPR_ID: CP032698_46
• CRISPR_location: 4443742-4443842
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_46

Consensus_repeat	Method
CGGGGTCTGGGGCAGAGCCCCAGG	CRISPRCasFinder

spacers of CP032698_46

>46.1|4443766|53|CP032698|CRISPRCasFinder
GGGCCCGGAACCATCCAACCCCGGGGCACGGGCGGGTGGGTGGGCGACGTGCC

CRISPR arrays and Neighbor proteins around CP032698_46

CRISPR arrays

The CRISPR arrays of CP032698_46

>merge|CP032698|46|4443742-4443842|CRISPRCasFinder
CGGGGTCTGGGGCAGAGCCCCAGGGGGCCCGGAACCATCCAACCCCGGGGCACGGGCGGGTGGGTGGGCGACGTGCCCGGGGTCTGGGGCGGAGCCCCAGG

>CP032698|46|36|4443742-4443842|CRISPRCasFinder
CGGGGTCTGGGGCAGAGCCCCAGG	GGGCCCGGAACCATCCAACCCCGGGGCACGGGCGGGTGGGTGGGCGACGTGCC
CGGGGTCTGGGGCGGAGCCCCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81845.1|4454846_4455005_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81836.1|4443285_4443534_-|hypothetical-protein	unknown	unknown	gnl|CDD|377461
CP032698.1|AYG81827.1|4434009_4434471_+|hypothetical-protein	unknown	unknown	gnl|CDD|377787
CP032698.1|AYG81841.1|4448111_4450037_-|Actin-cross-linking-toxin-VgrG1	unknown	unknown	gnl|CDD|226032
CP032698.1|AYG81828.1|4434638_4435616_+|Quercetin-2,3-dioxygenase	unknown	unknown	gnl|CDD|224655
CP032698.1|AYG81837.1|4443855_4445145_-|hypothetical-protein	unknown	unknown	gnl|CDD|237057
CP032698.1|AYG81833.1|4441414_4441690_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81835.1|4442513_4443215_+|55.5-kDa-and-49.5-kDa-sporulation-proteins	unknown	unknown	unknown
CP032698.1|AYG81840.1|4447660_4448101_-|hypothetical-protein	unknown	unknown	gnl|CDD|377431
CP032698.1|AYG81839.1|4445714_4447661_-|hypothetical-protein	unknown	unknown	gnl|CDD|274051
CP032698.1|AYG81834.1|4441686_4441908_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81844.1|4451243_4454840_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
CP032698.1|AYG81831.1|4436826_4439049_-|Phosphoserine-phosphatase-RsbU	unknown	unknown	gnl|CDD|369272
CP032698.1|AYG81843.1|4450761_4451199_-|hypothetical-protein	unknown	unknown	gnl|CDD|377718
CP032698.1|AYG81842.1|4450033_4450759_-|hypothetical-protein	unknown	unknown	gnl|CDD|212030
CP032698.1|AYG81846.1|4455001_4455454_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81830.1|4436199_4436796_+|HTH-type-transcriptional-regulator-AcrR	unknown	unknown	gnl|CDD|182632
CP032698.1|AYG81829.1|4435653_4436139_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81838.1|4445151_4445718_-|hypothetical-protein	unknown	unknown	gnl|CDD|274050
CP032698.1|AYG81832.1|4439400_4441167_+|Aspartate--tRNA-ligase	unknown	unknown	gnl|CDD|234775

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81836.1|4443285_4443534_-|hypothetical-protein	gnl|CDD|377461	pfam05119, Terminase_4, Phage terminase, small subunit.	4.44202e-08
CP032698.1|AYG81827.1|4434009_4434471_+|hypothetical-protein	gnl|CDD|377787	pfam07179, SseB, SseB protein N-terminal domain. This family consists of several SseB proteins which appear to be found exclusively in Enterobacteria. SseB is known to enhance serine-sensitivity in Escherichia coli and is part of the Salmonella pathogenicity island 2 (SPI-2) translocon. This entry contains the presumed N-terminal domain of SseB.	3.76005e-05
CP032698.1|AYG81841.1|4448111_4450037_-|Actin-cross-linking-toxin-VgrG1	gnl|CDD|226032	COG3501, VgrG, Uncharacterized protein conserved in bacteria [Function unknown].	1.4369e-21
CP032698.1|AYG81828.1|4434638_4435616_+|Quercetin-2,3-dioxygenase	gnl|CDD|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	6.37153e-68
CP032698.1|AYG81837.1|4443855_4445145_-|hypothetical-protein	gnl|CDD|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	6.27957e-09
CP032698.1|AYG81840.1|4447660_4448101_-|hypothetical-protein	gnl|CDD|377431	pfam04965, GPW_gp25, Gene 25-like lysozyme. This family includes the phage protein Gene 25 from T4 which is a structural component of the outer wedge of the baseplate that has acidic lysozyme activity. The family also includes relatives from bacteria that are also presumably lysozymes.	2.62986e-33
CP032698.1|AYG81839.1|4445714_4447661_-|hypothetical-protein	gnl|CDD|274051	TIGR02243, hypothetical_protein_SCD8A.17c, putative baseplate assembly protein. This family consists of a large, conserved hypothetical protein in phage tail-like regions of at least six bacterial genomes: Gloeobacter violaceus PCC 7421, Geobacter sulfurreducens PCA, Streptomyces coelicolor A3(2), Streptomyces avermitilis MA-4680, Mesorhizobium loti, and Myxococcus xanthus. The C-terminal region is identified by the broader model pfam04865 as related to baseplate protein J from phage P2, but that relationship is not observed directly. [Mobile and extrachromosomal element functions, Prophage functions].	3.15425e-159
CP032698.1|AYG81842.1|4450033_4450759_-|hypothetical-protein	gnl|CDD|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	1.06111e-07
CP032698.1|AYG81844.1|4451243_4454840_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	9.70079e-15
CP032698.1|AYG81830.1|4436199_4436796_+|HTH-type-transcriptional-regulator-AcrR	gnl|CDD|182632	PRK10668, PRK10668, DNA-binding transcriptional repressor AcrR; Provisional.	2.82312e-08
CP032698.1|AYG81843.1|4450761_4451199_-|hypothetical-protein	gnl|CDD|377718	pfam06841, Phage_T4_gp19, T4-like virus tail tube protein gp19. This family consists of several tail tube protein gp19 sequences from the T4-like viruses. This family also contains bacterial members which suggest lateral transfer of genes.	5.77974e-37
CP032698.1|AYG81831.1|4436826_4439049_-|Phosphoserine-phosphatase-RsbU	gnl|CDD|369272	pfam07228, SpoIIE, Stage II sporulation protein E (SpoIIE). This family contains a number of bacterial stage II sporulation E proteins (EC:3.1.3.16). These are required for formation of a normal polar septum during sporulation. The N-terminal region is hydrophobic and is expected to contain up to 12 membrane-spanning segments.	7.44389e-51
CP032698.1|AYG81838.1|4445151_4445718_-|hypothetical-protein	gnl|CDD|274050	TIGR02242, putative_secreted_protein, phage tail protein domain. This model describes a region of sequence similarity shared by a number of uncharacterized proteins in bacterial genomes, including Geobacter sulfurreducens PCA, Mesorhizobium loti, Streptomyces coelicolor A3(2), Gloeobacter violaceus PCC 7421, and Myxococcus xanthus. In all cases, the genomic region resembles a phage tail region, based on tentative identifications of neighboring genes. A region of this domain resembles a region of TIGR01634, another phage tail protein model. [Mobile and extrachromosomal element functions, Prophage functions].	9.3645e-36
CP032698.1|AYG81832.1|4439400_4441167_+|Aspartate--tRNA-ligase	gnl|CDD|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0

Protein sequences

>CP032698.1|AYG81836.1|4443285_4443534_-|hypothetical-protein
MQGTEPGRRVCVARIDQAERDLSERGLIVTAERGTVKNGAATIAAQYRTQLARYICELSLSPSARTAITAPEPEGDDSGVWD
>CP032698.1|AYG81835.1|4442513_4443215_+|55.5-kDa-and-49.5-kDa-sporulation-proteins
MGQIAGWIASDAGQHSEAEQFYRLGLSAARQAEDHTLAGNLAGSLAYQLSNTGREVEGIQLARAALDAAGTDAPAKARALYLDRVAWAHTKAGEFQPAIRALGEAGEALSQDRKGSEAPAYLYWVDSGELQVMEARVYTELRRPLRAVPLLRDVLSWYDATHTRELALYLSWLAVALSDANEPEEAVTVAERVMSLSADVASERTAERVRIVLARLEEFHDIPDVRALLDGAA
>CP032698.1|AYG81834.1|4441686_4441908_-|hypothetical-protein
MADNWSPTMGSYAVDTADNRIGEARRLFRGSMYLVPPGGGAEWAAPPNRLRPPTDAEVWQARVWTRPVGSSWQ
>CP032698.1|AYG81833.1|4441414_4441690_-|hypothetical-protein
MRTPRAVIRPVKHSIGTHPRGEITVSALCLDGACLWTLATTSDLKAADLAMMTHTGLSGHPTFARTFEDVALVRRLKLHARPDPCPLDRKQ
>CP032698.1|AYG81832.1|4439400_4441167_+|Aspartate--tRNA-ligase
MHRYRSHTCGELRASDVGADVRLSGWLHNRRDLGGILFIDLRDHYGITQLVARPGTAGAEALDKLSKETVVRVDGKVVSRGAENVNGELATGEIEIEVGEVEVLGAANPLPFTINADDGVNEERRLEYRFLDLRRERMHRNIMLRSAVIASIRSKMVALGFNEMATPILAATSPEGARDFVVPSRLNPGKFYALPQAPQQFKQLLMISGFDRYFQIAPCFRDEDARADRSPGEFYQLDVEMSFVEQEDVFQPIEKLMTEIFEEFGGGRQVTSPFPRIPFRESMLKYGNDKPDLRAKLELADITDVFEGSEFKAFAGKHVRALPVPDVASQSRKFFDGLGEYAVSLGAQGLAWVRVGEDGSLSGPIAKFLTEENVKVLTERLGLVPGHAVFFGAGEFDDVSKIMAGVRVEAAKRAGHFEEGVFRFCWIVDFPMYEKDEETGKIDFSHNPFSMPQGGLEALETQDPLDVLGWQYDIVCNGIELSSGAIRNHEPEIMFKAFEVAGYDRETVEREFGGMLKAFRLGAPPHGGIAPGVDRMVMLLADEPNIRETIAFPLNGNAQDLMMGAPTELDESRLRELNIALRKPVADK
>CP032698.1|AYG81831.1|4436826_4439049_-|Phosphoserine-phosphatase-RsbU
MRTEDVLAAIATGLWRWDNASGTVTLDAEAARLLGLPAQRVTLSEAAVRSRFHPVDWNEVDGIVHLALAEGTLAEVRLRIMDENGRVLRTVRSRSKPMLNGKSYLLIGTIQEVAEPQPGTTAAQPSITGDWRRSREAFLLDAGRALAEARSTSEVLRVAASLSMPGFSPDGLAVFGVAGERLTIIGHHGHNPGDDGPFTDMALDMDYPAADVVRNGRAIYLPSPQEYRRRFPATWPLAQRFDRQSWAFVPLIVAGRTIGAWMAAFKHPVAFTPDERSVLTTVARMLAQALARAGEAESERELSLGLQRSMMPTLGPEIPGMAVAARYVPTGGGLQVGGDWYDMIPLPGGGSRTDSGGGRFALVIGDVQGHDVRAAGLMGQLRIALRAYASEGHSPDAVLSRASRFLYGITESYGVPDPYGDGYEDYAPRFATCLYIEVDPATGTLDIARAGHPDPVIRTADGTALIRSTAGGLPLGIEADSDYPTTRLVLDPDETIMLCTDGLIETGGHDMASGWTRLRPVLEKHTDDNLEQLADELVQAVHGPSSHHTTGPLVDRREDDIALLLLRRNSLAGRPGAAPPAAVRRTALTVAQAEPEQIAGARRQLRELLHDWADEDQVDSAVLMISEMITNVLVHTDGDALLVAEARGPLGTRRLRVEVADASDELPHRRRPGELASSGRGLILMEMLADAWGVDPRGDGKSIWFELYETGGAGEADGGRGRGAREGAATDRGGQGPRAE
>CP032698.1|AYG81830.1|4436199_4436796_+|HTH-type-transcriptional-regulator-AcrR
MARRHLTPQDWSTAALRAMARGGVAAVSVNALAGELGATRGSFYWHFKDRDALLTAALEMWERKTTTALITELGDITDPRQRLRVLLTTGLGPGSSDGLEPAIVAHADHPAVARVLRRVTERRISYLTDLYADLGLAPAAARRQAVAAYATYLGWHELRHSVCDIVPEVATEGAVAGAALEHLITELARPAVHRAKPE
>CP032698.1|AYG81829.1|4435653_4436139_-|hypothetical-protein
MTVTKLADGEAEVGLGAAGGGRGRPRMTRWIPRLVTGLAALHFAVALSAASTFGDVARAGFWNAVPGNPQRGYETWFFIAGFGLLALGTLSQRIVRDTGILPAQLGWYLLAIGVPLQILCPVSGAPGLIVLGVLALIAARRGRAGESRTPVSPTAEREQGS
>CP032698.1|AYG81828.1|4434638_4435616_+|Quercetin-2,3-dioxygenase
MPAVTVENPLTLPRVTAPEGASARPVLAVTTAPQGFEGEGFPVRRAFAGINYKYLDPFIMMDQMGEVEYAPGEPKGTPWHPHRGFETVTYIIDGIFDHQDSNGGGGTITNGDTQWMTAGSGLLHIEAPPESLVVSGGLFHGLQLWVNLPARDKMMAPRYQDIRSGSVQLLTSPDGGALMRVIAGELDGHEGPGITHTPITMVHATLAPGAEITLPWRQEFNGLAYVLAGRGSVGAERRPVHAGQTAVFGEGGSLTVRADEKQDSHTPDLEVVLLGGQPIREPMAHYGPFVMNTRAELEQAFEDFQKGRLGTIPAVHGMTASGPQG
>CP032698.1|AYG81827.1|4434009_4434471_+|hypothetical-protein
MYGYDQNPGAQQQYAPPQQQMQGGYGEQPLYPEPSPPSLADAVRAFTTGSLSAEDFQQIFAGARVYCPRGDNPGFLALHNTQQPVIPMFTSLKELRRYAGKESKYFVITGAEVIDLLPTGYGFVLDMEGDHRMVFDAKAVEQMVDFAMRRMYG
>CP032698.1|AYG81837.1|4443855_4445145_-|hypothetical-protein
MTTPAMVPCPDCGTPARATGQSFCDSCGAFLRWSAPAAPPANAPAPDAAADTAPEAVTTPIPAVANPAEGAGAGAGAADRAGAASTAAPAAPAGSAAGASAGDTTPLPEVTPGARPDARTEARPDVRPDVRPDAAANEPVTPHPETRAPSVSDAARALLVPVQEPTARAPEAPGTVLPGRPEAARPKVRAATPAPAPENGTPCPACGTANHQHRSFCRSCATPLTPRREDNATGPYAGQRPPLHRDRKRWIARALTAAAVVALVVGGVFGGPPAARAVQDHFAKRVAVHPATWTASHWDPKHGPELAGDSYSNTWWGTGYAGDAQGTYLEATFGQPTDLLALLITPGTSKRQGQQSEQARPQEFDLLVTDTSGKAHVSHRSLNDGGVQRIDVRVRDAASVRLTLRSAFGAAKDKQVAIAEVEFFARSKN
>CP032698.1|AYG81838.1|4445151_4445718_-|hypothetical-protein
MSTRGSVDGLASSHPLGAQLPAVYADDDLAQRFVEGLDVVLAPLFNVLDCLEAYFDPALAPEDFVDWLTGWVGTELDGTEPLEIRRHAVATAVSLHRVRGTAQGLSRAVHLAFGVRPEISESGGAAWSARPLGPFPGDPKPSLRVTLRLSDPSSVDPHRLQAVVAAARPAHLPFTAEVSAKTLTPEGN
>CP032698.1|AYG81839.1|4445714_4447661_-|hypothetical-protein
MALPAPHLDDRRFQQFVDDAKRYIQQRCPEWSDHNVSDPGVTLIEAVAHMADQVVYRLNRVPEKNQLAFLDLLGVTLFPPSAARASVTFWLSAPQAEPVVLPRGTEVATGRTETEEAVVFASENDLTIVPCTLTHVLRQPAGSAPEDCSQDVLGNTDVSVFSSGPLPGDVLLFGLSAALPHCTAVLRLESRVDGVGVDPRQPPLVWEAWTADGWSECEVAEDTTGGLNRPGEVVLHMPTTHAVSRMGRLEAGWLRCRVVEAAPGQPFYSVSPTVRGASAFTIGGTTRVSHSESVRDESLGESEGVPGQRLMLAHAPVVGGVRLEVSAGEGWEEWETVDDFASSSPFDRHFTLDAATGELAFGPSVRQPDGSVRQFGAVPLKGAAIRASQYGTGGGRSGNVARGAIQVLRSSIPYISRVENREAARGGVDGETVEEAKIRAPIALRAQERAVTARDYEELARRAAPETARIACLAADAAESGDNAVRVLVVPQAVPDRGGRLRFEQLVPGDELLGRVTSFLDDRRPLGTRLAVGPPFYQGVTVVATLHAFRAAKADHVRDDALNTLYSYLDPLTGGAHGTGWPFGRPLRAGEIFAALQRVPGVELVDEVLLHPADPLTGRRGDATDRIDLSSSALLFPFDHRVRVIEAR
>CP032698.1|AYG81840.1|4447660_4448101_-|hypothetical-protein
MSEHFVGAGWAFPMRTEPGGGIALARRDREIEESMRLVLATAPGERPMRPEFGCAVHDLVFAPVNDATAGRIRYEVRTSLDRWEPRIEVEDVTVTPAPDEPTVLHIDVRYSVRGTNNPRSLVFPFYVIPSEGGDEPGPTAGESERH
>CP032698.1|AYG81841.1|4448111_4450037_-|Actin-cross-linking-toxin-VgrG1
MTEKTFTTVLHVQLNGTVLPDPLALRLVEGWVDSSVNVPAAFQLTFSDKDSKLTTKFPMLKIGAKVIISPFTDGRRGDPMMTGEVTALEMDSEPGSGRHLLVRGYDPGHRLLRNRRVEGYPNMTASDIVRRIAGQNGLKIGKIESTSAVYDLATQPNITDWDFLSRLAAENDVRLSFDNQGKLNFAGLDPASGAPSDTTPAAQSPYVLDFGANNLHSRATMTAAGQVRKVNVRGWDMRTRQKLQAPVPAVTSKDISADMTPGQVTLPFGASELTATHVPYTTLSQVTHAAKALADDVTGAFAELEVAITGNPELKPGTPIAVKGAGFPFEGKYTATGVRHVFASGDLYTTWLTVSGRQFRSLYGLASGGTEQAPPMPGVAVALVTNTKDPLRMGRVRLSFPWLSATYESDWCRVAQFGGKGGGGLLLPEVNDEVLCAFDRGSLEHPYVIAGLYNGIDKHTREPDNYPAVDPTSGEINWRSLTGRSGHTLEILESGGAARMESGIRLRTGRGRLHIQMNEARTSLTIHSDGSVDIRGTRSVDIEAGGDLSLKAGGNLSLKSGGAIEIDAGMAINVKAGLAFDVKAGGEASIGAGGMLALNSIGATTINAIANLTIDSATILVNAPAFSIQSAAPLVNGAPII
>CP032698.1|AYG81842.1|4450033_4450759_-|hypothetical-protein
MAAPVGGKAAKGLSRATLAIHQPPTDLGGSMGGRIGEVKFQFNPSQVQLGRSANWITTPAISYNRGAPPKFTGAMPASLQLEVFLDASGTPSSNTVQSQVELLLSCCEVTSQSISAKAPSPPWVEFSWGSFSTVQFVAYVTSVNASYTLFSPNGMPLRATCTLALTEVASETKRQNPTSGALSARRVHRTVAGDTLASLAWREYGDATQWRTIAEANEIDDPMRLRPGTELLLPASSEGTT
>CP032698.1|AYG81843.1|4450761_4451199_-|hypothetical-protein
MPSTLDPGSTVFFKLTIDGQNLGLFNGCDGLASEVEVEQRQEGGNNGFVWQLPTRVTFSTIRLTRPLTADTSKVAAWISSLATGITRPTAQIAALRADGSIVAQWGLVEVLPVRWTGPSLDPASPSVATETLEIAHHGFTDAGGA
>CP032698.1|AYG81844.1|4451243_4454840_-|hypothetical-protein
MGLFKRRRNRPEAGDAGGAGQAGEATGASPASPSPDPAPVPAPADGGWAATAPMQRALAAPRLTAESGFGSTLAAHQDLSVVRPLTHAVSPTAPHGVLHNALTPVAGAPSPLPLQLLRLPVASRPAPEPPAEDEATPASAPAWGSAPVQRAVAPAPAAATPAARRSATPSGGTANGAAGPAPASGSGAAGPASASGSAAPGPAPASGSGAAGPAPAVQRATSAPANTPSAAPGSGRATRRPAAPSTGPAHTPAAPAATPSTSGSAPGVQRSAASPASPASTPGVVPGSPAVTSTGPARDQVVPPVRPAERAGPTPGPASAPRSASTPGPASRPATPAPPAASGATPAVQRSATPPGTRPAAAPNTPGAVAGPAPAVQRAATPPRTPADRPGATPAPARGSSTSPAAPGVEPSADGTNEPRPASPPAAPGPGPAVQRAASPSADARNNPASPPAVRHAATPNPSSTPGPAPAVQRAQPRATTPPVRADVPGAGTGRPGGSEASERGGPGGSRAAHSTPAVQRAAAPESAPTENPGRSSVTPAASGPTPAVQRTTPPTPAAPDALPVRGEGATRPAPATETSPTTPAPSAPRRADRPVPASPIGPPIQRSTAVPPGATAHPARRPAATPPGSGSGPASRAADAPASIQRAATPVSPAADASGPARTAPGAASGSAPFGAAPLGAAPGGSSPSGSFPSGAAPSGAVPSSSTPRATSPVGPSSIPPGSPGQGAPGVARGLGSPSSGPAGPRSAEGAQGASGATAPVQRAVTAPTSRPDTAPLSSSPQRAAQNPPHSSPAGDAMPVRGDAPGGSTPVSPLPVRGLTPGGSASVPSTPVRGLNPGGPASVPTPMPVARAVAGSGSTPLLPTPVQRFAAPGRSLTSAPRPTRPSHHLDPVGVVRRPSEPVESPPATPAPVLTPAPAPAPTPAAPAAPAAPPVQRKPVVRRVSRVQSTGPDVARRRPLIGAPITPAPAPAQAPAPERSPFAAPTPEPPVVQRAAAPAPPAEPVAPAEPATPLRKVRVPGPTPLQRAPLAGPPLASARPLTTRHQSVPSTPGPVVPPAPAPLRRAPASADSRPVVPLSGPAPRPGTARPTVQRAAEPTPAPVVPVRRNSPPPAPPAPAPSPPPPIPAPAAAPVQRRSDPPPVQRTASATQAAAPVPDADQPSPDIDALARRLVAPLSRLLRAELRGDRERLGRLRDR
>CP032698.1|AYG81845.1|4454846_4455005_-|hypothetical-protein
MTYAADRIEEETAYLAYHFHWDMDSILDLEHADRRAYVRRVAALVEQGEGER
>CP032698.1|AYG81846.1|4455001_4455454_-|hypothetical-protein
MRREGPGVPGGAVAGAETPSASGGARETLRTEFEFELPRGYVDESGTVHRRGAMRLATARDELLPLRDVRVRENPAYLSVVLLGRVITRLGTLGDVHDGTVENMFASDLAFLQDFYRQINAEGHTRAAVACPHCEQSFEVELAGSRLGES

Crispr_ID: CP032698_47

• CRISPR_ID: CP032698_47
• CRISPR_location: 4480701-4480951
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP032698_47

Consensus_repeat	Method
TTTAGGGGCGCGGGGAACTGCGCG	PILER-CR
TTTAGGGGCGCGGGGAACTGCGCG	CRT

spacers of CP032698_47

>47.1|4480725|33|CP032698|PILER-CR,CRT
CCCAGCCACGCACGACCCGCAGACGAAAACGGG
>47.2|4480782|32|CP032698|PILER-CR,CRT
AGAAGCGGGCACGGTCCGCAGGTTCGAGAGGG
>47.3|4480838|36|CP032698|PILER-CR,CRT
CCCAGCCACGCACGGCCCGCAGACGAAAACGGGTTT
>47.4|4480898|30|CP032698|CRT
AAAAGTGGGCCCGGTTCGTGGTGGCGGGGG

CRISPR arrays and Neighbor proteins around CP032698_47

CRISPR arrays

The CRISPR arrays of CP032698_47

>merge|CP032698|47|4480701-4480951|PILER-CR,CRT
TTAAGGGGCGCGGGGAACTGCGCGCCCAGCCACGCACGACCCGCAGACGAAAACGGGTTTAGGGGCGCGGGGAACTGCGCGAGAAGCGGGCACGGTCCGCAGGTTCGAGAGGGTTTAGGGGCGCGGGGAACTGCGCGCCCAGCCACGCACGGCCCGCAGACGAAAACGGGTTTTTTGGGGGCGCGGGGAACTGCGCAAAAAGTGGGCCCGGTTCGTGGTGGCGGGGGGCTAGGGGCGCGGGGAGGTGATGG

>CP032698|47|13|4480701-4480897|PILER-CR
TTAAGGGGCGCGGGGAACTGCGCG	CCCAGCCACGCACGACCCGCAGACGAAAACGGG
TTTAGGGGCGCGGGGAACTGCGCG	AGAAGCGGGCACGGTCCGCAGGTTCGAGAGGG
TTTAGGGGCGCGGGGAACTGCGCG	CCCAGCCACGCACGGCCCGCAGACGAAAACGGGTTT
TTTGGGGGCGCGGGGAACTGCGCA

>CP032698|47|5|4480701-4480951|CRT
TTAAGGGGCGCGGGGAACTGCGCG	CCCAGCCACGCACGACCCGCAGACGAAAACGGG
TTTAGGGGCGCGGGGAACTGCGCG	AGAAGCGGGCACGGTCCGCAGGTTCGAGAGGG
TTTAGGGGCGCGGGGAACTGCGCG	CCCAGCCACGCACGGCCCGCAGACGAAAACGGGTTT
TTTGGGGGCGCGGGGAACTGCGCA	AAAAGTGGGCCCGGTTCGTGGTGGCGGGGG
GCTAGGGGCGCGGGGAGGTGATGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81865.1|4480294_4480456_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81861.1|4475710_4476697_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81872.1|4488525_4488762_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81874.1|4489046_4489877_-|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG81862.1|4476711_4478199_-|Putrescine-importer-PuuP	unknown	unknown	gnl|CDD|223605
CP032698.1|AYG81875.1|4490045_4491983_+|hypothetical-protein	unknown	unknown	gnl|CDD|223605
CP032698.1|AYG81864.1|4479563_4480220_+|Extracellular-small-neutral-protease	unknown	unknown	gnl|CDD|280248
CP032698.1|AYG81860.1|4474215_4475580_-|hypothetical-protein	unknown	unknown	gnl|CDD|378410
CP032698.1|AYG81863.1|4478403_4479348_-|Hca-operon-transcriptional-activator-HcaR	unknown	unknown	gnl|CDD|176106
CP032698.1|AYG81859.1|4472492_4474073_-|Methionine--tRNA-ligase	unknown	unknown	gnl|CDD|237012
CP032698.1|AYG81873.1|4488786_4489050_-|hypothetical-protein	unknown	unknown	gnl|CDD|377231
CP032698.1|AYG81870.1|4486262_4487891_+|putative-MFS-type-transporter-EfpA	unknown	unknown	gnl|CDD|129794
CP032698.1|AYG81867.1|4483538_4483937_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81856.1|4468511_4470494_-|ATP-dependent-zinc-metalloprotease-FtsH	unknown	unknown	gnl|CDD|223540
CP032698.1|AYG81871.1|4488047_4488515_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81866.1|4483081_4483447_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81857.1|4470490_4471123_-|hypothetical-protein	unknown	unknown	gnl|CDD|379449
CP032698.1|AYG81869.1|4485441_4486134_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81868.1|4484220_4485297_+|Tryptophan--tRNA-ligase-2	unknown	unknown	gnl|CDD|234866
CP032698.1|AYG81858.1|4471231_4471909_-|Transcriptional-regulatory-protein-DegU	unknown	unknown	gnl|CDD|225107

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81875.1|4490045_4491983_+|hypothetical-protein	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	5.74619e-27
CP032698.1|AYG81874.1|4489046_4489877_-|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.46347e-09
CP032698.1|AYG81862.1|4476711_4478199_-|Putrescine-importer-PuuP	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	4.36185e-35
CP032698.1|AYG81864.1|4479563_4480220_+|Extracellular-small-neutral-protease	gnl|CDD|280248	pfam02031, Peptidase_M7, Streptomyces extracellular neutral proteinase (M7) family.	1.36643e-67
CP032698.1|AYG81860.1|4474215_4475580_-|hypothetical-protein	gnl|CDD|378410	pfam10138, vWA-TerF-like, vWA found in TerF C-terminus. vWA domain fused to TerD domain typified by the TerF protein. Some times found as solos.	2.06504e-49
CP032698.1|AYG81863.1|4478403_4479348_-|Hca-operon-transcriptional-activator-HcaR	gnl|CDD|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	5.82332e-27
CP032698.1|AYG81859.1|4472492_4474073_-|Methionine--tRNA-ligase	gnl|CDD|237012	PRK11893, PRK11893, methionyl-tRNA synthetase; Reviewed.	0
CP032698.1|AYG81873.1|4488786_4489050_-|hypothetical-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.13872e-22
CP032698.1|AYG81870.1|4486262_4487891_+|putative-MFS-type-transporter-EfpA	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.95995e-78
CP032698.1|AYG81856.1|4468511_4470494_-|ATP-dependent-zinc-metalloprotease-FtsH	gnl|CDD|223540	COG0464, SpoVK, ATPases of the AAA+ class [Posttranslational modification, protein turnover, chaperones].	3.30596e-22
CP032698.1|AYG81857.1|4470490_4471123_-|hypothetical-protein	gnl|CDD|379449	pfam14065, DUF4255, Protein of unknown function (DUF4255). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 190 and 320 amino acids in length.	1.2533e-45
CP032698.1|AYG81868.1|4484220_4485297_+|Tryptophan--tRNA-ligase-2	gnl|CDD|234866	PRK00927, PRK00927, tryptophanyl-tRNA synthetase; Reviewed.	1.26374e-118
CP032698.1|AYG81858.1|4471231_4471909_-|Transcriptional-regulatory-protein-DegU	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.94997e-27

Protein sequences

>CP032698.1|AYG81865.1|4480294_4480456_+|hypothetical-protein
MVAGKFVRHDPRTWEGGELALCPGSKRRAPLDATHPTLAAFPHPPSPGQLPLF
>CP032698.1|AYG81864.1|4479563_4480220_+|Extracellular-small-neutral-protease
MRHPRTFAVSAALGLALAGFGAIPATAAAPAAAPAAGSTAHYTAAGKHTAANDRAFYDAVMKSVAKKRAANPLAASVTVYYSASNAPSFRSQISQSAQIWNSSVQNVRLAESSSGADFQYYEGNDPQNGSYASTDGHGNGYIFLDYGQNQQYYSVRVVAHETGHVLGLPDHYSGPCSELMSGGGPGTSCRNAYPNSTEKSRVNSLWRNGLASAFKPAA
>CP032698.1|AYG81863.1|4478403_4479348_-|Hca-operon-transcriptional-activator-HcaR
MDLEVRHLRVVCAIADAGSLHGAARALGTSQPALTTQLRRIENTLGGRLFTRERTGCVPTALGQGVVGRARPLLASLSALVTETRAAAARTTGGERLRIGSTASRAIPGWLRRLRERLPSTETELQVAVSATALLRRVASGELDMAFVHEVEGCPLRVPPGLDIRTLVEREPQFVCLAVEHPAARHPVVDLADLAADQWMVDPSVDGEWEGLRRVLNAAGLNPRVLHGDYLTAAGLVATGEVVTLCQPTSRPRPDLAVRPLRNDPLGVRLFLAVRSGEYRGELAGAGADLEASYWEAASHSPAYRDWLEERGRR
>CP032698.1|AYG81862.1|4476711_4478199_-|Putrescine-importer-PuuP
MRTTTGGRGLQSDALSTFDTVVMAIAGSAPAYSLAATSSVLVGAAGLASPAALLYCALPMLGIVLAFGRLGRIDVNAGAAYSWVGRTLHPFLGFLSGWALVVAATLFMVAGSLPAGQLTLGLFDPALAHDTALATATGAGWFLLMLAVVLGGARLSARAQLIVSGVELAILGGFSVAALAHLAEGDGVVPFSWGWLGFGHFDGVSGFAVGTLIAAFYYWGWDVTSNLSEETRDSRRTAGLAALVGVGVVFALFLAFTIAMNALLTSDEIESGQSNVLALLGARIWPGVGGKLMVLAVVLSTIATLETTLIQVTRSLFAMGRDRTMPGALGTVHRRWNTPWVAIVVVGAVALLLFVASNALGSVRDIMSDALAAIGLQTTLYYGLAGLAAVVAYRKTLTESVASFLLGGVWPLLGSLFMFCVFAASLTRLSAAALTLGIGSLLAGLVPMLWYWRRGSAYYRPARLDATRSFDAGAGRPNTPTRSSGYVNAGHPTDF
>CP032698.1|AYG81861.1|4475710_4476697_-|hypothetical-protein
MAALRRRSDRRAAPRFDPDLGDRALTVARHDIAIGRWQGVRDLLRATGENWPLRSHRVRAVAGAAAGSSVVEAWRAAEPNSPDAAVLRAATEVTRVFNGAIAAGRGAGTPRDRVDAAVRACLRAAATHPTDPTPWASLLTVVRLYEGGVARRELRTWWDELRRRDPYHLEGHIQMLRYFSARWHGTHGSMYDFARDAAGAAPAGSPLPVLVQIARVEEYRYVSDAAKGRPVRGFGQHWTHELAVTELHRTYDRWLGGRPPGPARAEEAAELNYLAHAASCAGLAPEAGALVGLLGERVATVPWVYTGDPAQQILRWRGRAGDRSPRRT
>CP032698.1|AYG81860.1|4474215_4475580_-|hypothetical-protein
MGIRSLLRKVFGRDRTERAEQTAASVPPQTERAPEAVEAPATTTDGATAAPSVPAPGRRDLSPAEALVAAAFDGPAPADSSRPSEPSAPSHPSPSPSSPSTTDSSSSADSSRADTAPEPVVAEVPQPRTEAKPEKAAEPEQAEVPEKAAVPEKAEVTEKVAEPEPEPVQAEPEPVKAEPEPVKAEPEPAKVEADVAPVAEPEPEPEPVQAEPEPEPVKADREPEPVKAEPAPVAQSALSAAKVKSRAPGLAGAYKAAGAALKKAGIAGARAKVYLVLDRSGSMRPYYKDGSAQGLAEQVLALAAHLDADATVHTVFFSTDIDGSVELGLDAYEGLVDETHAGLGRLGRTSYHRAVEEVVEHVEKSGHEGPVLVVFQTDGAPHAKLPARQALADVADKPLYWQFVAFGEDDSKAFDFLRTAEGEHDHVGFFHAGPAPRELSDAEVYRGLLSSYRP
>CP032698.1|AYG81859.1|4472492_4474073_-|Methionine--tRNA-ligase
MPSPTYYVSTPIYYVNDAPHLGHAYTTVAGDVLTRWHRQRGEKVWYLTGTDEHGQKIMRTAEANGVTPQEWCDKLVGEAWQPLWEHLNIANDDFIRTTQKRHTDRVQEFVQDLYDKGEIYKGGYEGPYCVGCEEYKLPGDLIRAEDGTELCAIHKKPVELLKEENYFFKLSEYGPKLLEFYEANTGFIQPESARNEVLNFVRQGLQDLSISRSTFDWGVPVPWDPQHVIYVWVDALLNYATAVGYGADQARFEEVFPADVHLVGKDILRFHAIIWPAMLMANGLPVPGKVAANGWLMVGGEKMSKSNLTGIKPQDLTSHFGVDAYRWYFLRAIAFGQDGSFSWEDFTARYTSELANDYGNLASRVAAMVGKYFGGELPAAAADGAAEAAVQEGLARAAAEADRRIGDELDFQGGILAVFDFVKQVNGYLTEQEPWKVAKDESDAGRARLATILYTAAEALRGVAVLLNPVMPDTSQQLWDSLGAEAALGSLADQRVQEAGVWGALTPGAKVTKGAVLFPRLEEKPA
>CP032698.1|AYG81858.1|4471231_4471909_-|Transcriptional-regulatory-protein-DegU
MPLLANRVTVTVHASDPLSRAGVISHLQHQPTVEVLRDTRESRETDGRPADPAVAVMLVDQVDDTASAELRRVVRGGEQRVVLIARELREPDLLTVVEYGVRAILWRHQATEQRLLKAVHSAARGEGELPPDLISRLLVQVGRLRRSETTSASAGSSSAAPLFGMAPREVDVLRLVAEGLDTRQISEKLAYSERTVKNILHALMTRLQLTNRAHAVAYALREGYI
>CP032698.1|AYG81857.1|4470490_4471123_-|hypothetical-protein
MIHEIDEALRRILRGGALPEGTGEVVFEAPTRDWAARRNTPTLNAYLYDIREDVARRERGSYAERDANGVVLRRRQPPRWFRLSYLLTAWTSRPEDEHRLLSGVLACLLPHEMLPQEHVPRALDAYKVALPITVAVPPAESRSLADIWSALGGELKPSLDVVITTPFPVTPVYPVAPPVTEGVITVRGRDGVPDDAKPRLMRTPQEGGSR
>CP032698.1|AYG81856.1|4468511_4470494_-|ATP-dependent-zinc-metalloprotease-FtsH
MNEAAVALLLRLDHLRATVASLVAARSADDPTAQDPLRGLYVSAETAARLADSPAPPPPAPDDSFAPAPGDRVTALTGGFGLTALDVRLLVAALAPDVDRRFEPLYGYLNDDVGRRRASVALALELAGTGPHDPAARARLHPAAPLISGGLLVLEDEDRPLPGRALRVPERVVAHLLGDDTLDGQLDGAVVELLAPGGAAPETGLAARIALAPAPVRVHLRERRAGSGADAVTAALRGAGRAVLRHRPERTDPAAARALLREARLRGAGTAVVVELPEEQPGPLVRELAAPDVTVVFAGTLPYDPTWAPAAGLLALEDTAAETDPLTAWTEELPGYEGDLAEAVGPYRLGAGQVRRAARGALALAGFDGVPVGLGHVQKSARLLSAPLLDRHARRVRPAVGFQDLVLPEEPLAMLHELAGRARHRDRVLGEWRLRTGGGRGRGVVALFAGDSGTGKTLAAEVVAGELGLDMYVVDLSSVVDKYVGETEKNLEKIFVEADRTDSVLLFDEADAVFGKRSEVKSSHDRYANLESAYLLQRLEAFDGIAVLTTNLRANIDEAFTRRLDLVVDFPFPDVALRATLWRGCLAGVPQEDGLDAELDACAKEFELAGGAIRSAAVTAGYLAAGRGSAVTAADVRAGARREYVKSGRLVPGAGTAWAP
>CP032698.1|AYG81866.1|4483081_4483447_-|hypothetical-protein
MGNPGCRGRVRSFWSTVLVVVAAALVPLVAVRRRAPVGAGAVAGAGIGLAVGAAVVRVVVAVGRSRTLDGLPPDADPSAAGAVYDTLTDALTTAAWAVLAFGLALALGAWLAGRSATRRDR
>CP032698.1|AYG81867.1|4483538_4483937_+|hypothetical-protein
MATHASVPVTSRSAAPHHLSRAVLAVPVVLGVVYGFYAAAILRGGGAVTGGQIVLGVVSGAAVMVLGLCLLRFQSALPRELRATAYATLFGGGMGFLYSLAGHSVLRSSGIGAVLGGGMFLVAFYVFYTHED
>CP032698.1|AYG81868.1|4484220_4485297_+|Tryptophan--tRNA-ligase-2
MTTASTTATATTTATTTATATTTATTPAPTHARGTDRVLTGDRPTGPLHLGHYFGTLHNRVRLQNEGVDLFLVIPDYQVLTDRDVAERLSDHVEGLVLDYLGAGVDPSRATVFTHSAVPALNQLLLPFLSLVSVAELGRNPTVKDEIAHSRQSAVSGLMYTYPAHQAADILFCKANLVPVGKDQEPHLELTRTIARRFNERYGPVFPEPRTLLSEAPLLLGTDGTKMSKSRNNSLALKASSDETARLIRGAKTDATRLIAYDPEHRPEVSNLVLLTALCEGRDPHEVAADIGDGGASALKAAATEAVNTYFAPLRARRAEYAQDMGYVRELLRAGNAKANEVAEATLAEVREAMGMFR
>CP032698.1|AYG81869.1|4485441_4486134_+|hypothetical-protein
MAGQRGRGVRNVRGWWLVLPVAALLVSGCTGGSGAGAESGSGSGSATGKPSAGASASAGVSPGPSASAGAYDPATYAPQVRTYAKKAGVSAQLLMAVLYNEDYKPHDPAFERSWQKYKPDAAFGIANMHRAAFDQTKRGRPFAARKWEELPDDRALAVEAAAWYLHDMSAQLPAHWAGGYSRDELMALGYNAGGGNMAAFARGAKPGSQASDYLTRLRDNWKKAGAAVAG
>CP032698.1|AYG81870.1|4486262_4487891_+|putative-MFS-type-transporter-EfpA
MGRHTKDSVEVGRAERIAAASDGLAADGQPPPSTGAHPAAPPPPAAYTGEGGPPPQAPHTGARHEHRWLVLGVIALAQLMVVLDATIVNIALPSAQQDLGFSDGNRQWIVTAYALAFGSLLLLGGRIADLVGRKVVFLIGLVGFAVASAIGGAAPNFEVLVTARALQGVFGALLAPAALSLLTTTFTDPKERAKAFGIYGAVAGTGGAVGLLLGGILTEYLDWRWCLYVNLLFAALAFLGALRLLHPGAPSDRPKLDIPGTVLVSAGLFCIVYGFSNAETHAWSSPKTWGFLVVGGVLLIAFAWWQTRAKHPLLPLRVVLDRDRGASYLAMFISGAGMFGVFLFLTYYLQQILHYTPVKTGLAFLPMVFAMIVSSVVAQNKLVPRLGAKPIVPLGMGLGAAGLAWMTALDATSGYAGHVLPPLLVMGVGMGLIFAPAMSMATAGVAAHDAGVASAMVNTSQQVGGSIGTALLNTLATSAATSYLVGRQPTPGARVQAQLQSYSTAYWWSAAFFALGLVVSVILYRKGPPRQAVGPTEGPVHM
>CP032698.1|AYG81871.1|4488047_4488515_+|hypothetical-protein
MSATVAMEMPVQVVEGPAKATNATEMPVLGLPTWYFPLVGLFAGLFDMAPAYPALYALIPVVAVVQIVLAFTVLRPRIRAMKALWKNKRTRFLAIGLVAVRFVIRYGLGMAGLALGAATGHLVLGIVMAAVGTAMAWGDQWLILRTLRRAQAPTV
>CP032698.1|AYG81872.1|4488525_4488762_-|hypothetical-protein
MAIPQLPPVVPASCPLCEGGLETVELRMTNAATAHLIAKFYRPEKMFASKSYVMASACRECGHVLMFLENRGILAPKG
>CP032698.1|AYG81873.1|4488786_4489050_-|hypothetical-protein
MNITRSLAAARWRKSSYSNAEGGDCLEVAEGAWRKSSYSNDEGGDCVEVADGFGDVVPVRDSKVPSGPVLLVDATAWTRFVGAVKGV
>CP032698.1|AYG81874.1|4489046_4489877_-|hypothetical-protein
MTRPKDLNPWDSPRAFYGTELRRHREAAGLSQEELGALVFCSGTYIGQMESATRRPTKEMAKLLDAALHTDGILTRMCEAMEQASQHAEYFQLAAELESMASAIFHWTPMVVPGLLQTAAYTRALTRAGRPFATDEDVERNVSTRKERAKLLDGPEAPELWCILHEAALRIRVGDPGVMREQLAHIGELAQAGRIVVQVLPSEAGVLPLMHSSVKVMTFVDAPPVIYLEAARSGQLLDTPALVASYIKTYDLARAVALSPTASLAMIQAAMEDYAP
>CP032698.1|AYG81875.1|4490045_4491983_+|hypothetical-protein
MGVSSSVKRMLVGRPLDTSRLGETLLPKRLALPIFCSDPLSSVAYATEEILLILALGGVGLLHLAWYAAAAIVFLLVVVIASYRQTCHAYPGGGGAYVVSAENLGPTAALTAASALLVDYVLTVAVSVVSGVAAITSAVPSLAPHQVALSVCFVVLLTVMNLRGVRESGRIFAIPTYGFVCVIYLMFAFAAVRLATGATIRAESADLPLHATGTYAGIAVVLLALRAFASGCTALTGVEAISNGVPAFQKPKSRNAANTLAAMGLLSVTMFVGITALAMTYRVHVAAVPTQLGLPAGATPSTALAQIARATFGNADLLFYLVQAFTAGVLVLAANTAFNGFPMLASILARDRYAPRQLYNRGDRLVYSNGVVLLALAAVALIVAFDAQLTRLIQLYIIGVFVSFTLSQAGMVKHWRKVLATPEGRDDRRRIHRSLAINAVGATLTGLVLVIVLITKFTHGAWLVVIAMPVLFFGMKGVRRHYDQVAREIAVGPDARPPRPSRHHAFVLVSRVQAPTLKAIGFAQALRPDTLTALTVAADEDAEGLREQWTAYDLGVPLTIIDSPYREVVGPVLAHVRETAEADSGAMVSVVIPEYIVGRWWEVPLHNQNALRLKARLLFMPGVTVIDVPYRLRSARQPVLNRRTG

Crispr_ID: CP032698_48

• CRISPR_ID: CP032698_48
• CRISPR_location: 4494082-4494184
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_48

Consensus_repeat	Method
CCTGGGGCTCCGCCCCAGCCCCCG	CRISPRCasFinder

spacers of CP032698_48

>48.1|4494106|55|CP032698|CRISPRCasFinder
AGCCCCTTTGCCCACCCACCCGCCCGTAGGCGCAGGGTCGGATGGTCCGGGCCTT

CRISPR arrays and Neighbor proteins around CP032698_48

CRISPR arrays

The CRISPR arrays of CP032698_48

>merge|CP032698|48|4494082-4494184|CRISPRCasFinder
CCTGGGGCTCCGCCCCAGCCCCCGAGCCCCTTTGCCCACCCACCCGCCCGTAGGCGCAGGGTCGGATGGTCCGGGCCTTCCTGGGGCTCCGCCCCAGACCCCG

>CP032698|48|37|4494082-4494184|CRISPRCasFinder
CCTGGGGCTCCGCCCCAGCCCCCG	AGCCCCTTTGCCCACCCACCCGCCCGTAGGCGCAGGGTCGGATGGTCCGGGCCTT
CCTGGGGCTCCGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81882.1|4498128_4498887_+|Precorrin-6A-reductase	unknown	unknown	gnl|CDD|236144
CP032698.1|AYG81878.1|4493649_4494072_-|Tetracycline-resistance-protein-TetO	unknown	unknown	gnl|CDD|239682
CP032698.1|AYG81875.1|4490045_4491983_+|hypothetical-protein	unknown	unknown	gnl|CDD|223605
CP032698.1|AYG81874.1|4489046_4489877_-|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG81885.1|4501119_4502469_-|hypothetical-protein	unknown	unknown	gnl|CDD|274131
CP032698.1|AYG81883.1|4498871_4500458_-|Cobalamin-biosynthesis-protein-CobIJ	unknown	unknown	gnl|CDD|381173
CP032698.1|AYG81879.1|4494437_4495694_+|Precorrin-6Y-C(5,15)-methyltransferase-[decarboxylating]	unknown	unknown	gnl|CDD|225151
CP032698.1|AYG81876.1|4492349_4492616_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81884.1|4500454_4501123_-|Precorrin-8X-methylmutase	unknown	unknown	gnl|CDD|181352
CP032698.1|AYG81873.1|4488786_4489050_-|hypothetical-protein	unknown	unknown	gnl|CDD|377231
CP032698.1|AYG81870.1|4486262_4487891_+|putative-MFS-type-transporter-EfpA	unknown	unknown	gnl|CDD|129794
CP032698.1|AYG81886.1|4503441_4507149_+|Aerobic-cobaltochelatase-subunit-CobN	unknown	unknown	gnl|CDD|235663
CP032698.1|AYG81869.1|4485441_4486134_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81881.1|4496904_4498041_-|Cobalt-precorrin-5B-C(1)-methyltransferase	unknown	unknown	gnl|CDD|234615
CP032698.1|AYG81887.1|4507213_4508887_-|ECF-RNA-polymerase-sigma-E-factor	unknown	unknown	gnl|CDD|349398
CP032698.1|AYG81871.1|4488047_4488515_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81888.1|4509067_4509901_-|Ubiquinone-biosynthesis-O-methyltransferase	unknown	unknown	gnl|CDD|379312
CP032698.1|AYG81877.1|4492623_4493517_-|Chitin-binding-protein-CbpD	unknown	unknown	gnl|CDD|376983
CP032698.1|AYG81872.1|4488525_4488762_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG81880.1|4495690_4496434_+|Precorrin-4-C(11)-methyltransferase	unknown	unknown	gnl|CDD|225430

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81882.1|4498128_4498887_+|Precorrin-6A-reductase	gnl|CDD|236144	PRK08057, PRK08057, cobalt-precorrin-6x reductase; Reviewed.	1.94321e-110
CP032698.1|AYG81878.1|4493649_4494072_-|Tetracycline-resistance-protein-TetO	gnl|CDD|239682	cd03711, Tet_C, Tet_C: C-terminus of ribosomal protection proteins Tet(M) and Tet(O). This domain has homology to the C terminal domains of the elongation factors EF-G and EF-2. Tet(M) and Tet(O) catalyze the release of tetracycline (Tc) from the ribosome in a GTP-dependent manner thereby mediating Tc resistance. Tcs are broad-spectrum antibiotics. Typical Tcs bind to the ribosome and inhibit the elongation phase of protein synthesis, by inhibiting the occupation of site A by aminoacyl-tRNA.	4.64582e-13
CP032698.1|AYG81875.1|4490045_4491983_+|hypothetical-protein	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	5.74619e-27
CP032698.1|AYG81874.1|4489046_4489877_-|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	4.46347e-09
CP032698.1|AYG81885.1|4501119_4502469_-|hypothetical-protein	gnl|CDD|274131	TIGR02435, Precorrin-3B_synthase, precorrin-3B synthase. An iron-sulfur protein. An oxygen atom from dioxygen is incorporated into the macrocycle at C-20. In the aerobic cobalamin biosythesis pathway, four enzymes are involved in the conversion of precorrin-3A to precorrin-6A. The first of the four steps is carried out by EC 1.14.13.83, precorrin-3B synthase (CobG), yielding precorrin-3B as the product. This is followed by three methylation reactions, which introduce a methyl group at C-17 (CobJ; EC 2.1.1.131), C-11 (CobM; EC 2.1.1.133) and C-1 (CobF; EC 2.1.1.152) of the macrocycle, giving rise to precorrin-4, precorrin-5 and precorrin-6A, respectively. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	1.55251e-52
CP032698.1|AYG81883.1|4498871_4500458_-|Cobalamin-biosynthesis-protein-CobIJ	gnl|CDD|381173	cd11646, Precorrin_3B_C17_MT, Precorrin-3B C(17)-methyltransferase (also named CobJ or CbiH). Precorrin-3B C(17)-methyltransferase participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. This model includes CobJ of the aerobic pathway and CbiH of the anaerobic pathway, both as stand-alone enzymes and when CobJ or CbiH form part of bifunctional enzymes, such as in Mycobacterium tuberculosis CobIJ where CobJ fuses with a precorrin-2 C(20)-methyltransferase domain, or Bacillus megaterium CbiH60, where CbiH is fused to a nitrite and sulfite reductase-like domain. In the aerobic pathway, once CobG has generated precorrin-3b, CobJ catalyzes the methylation of precorrin-3b at C-17 to form precorrin-4 (the extruded methylated C-20 fragment is left attached as an acyl group at C-1). In the corresponding anaerobic pathway, CbiH carries out this ring contraction, using cobalt-precorrin-3b as a substrate to generate a tetramethylated delta-lactone.	1.34551e-114
CP032698.1|AYG81879.1|4494437_4495694_+|Precorrin-6Y-C(5,15)-methyltransferase-[decarboxylating]	gnl|CDD|225151	COG2242, CobL, Precorrin-6B methylase 2 [Coenzyme metabolism].	1.3672e-73
CP032698.1|AYG81884.1|4500454_4501123_-|Precorrin-8X-methylmutase	gnl|CDD|181352	PRK08285, cobH, precorrin-8X methylmutase; Reviewed.	8.46994e-132
CP032698.1|AYG81873.1|4488786_4489050_-|hypothetical-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.13872e-22
CP032698.1|AYG81870.1|4486262_4487891_+|putative-MFS-type-transporter-EfpA	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.95995e-78
CP032698.1|AYG81886.1|4503441_4507149_+|Aerobic-cobaltochelatase-subunit-CobN	gnl|CDD|235663	PRK05989, cobN, cobaltochelatase subunit CobN; Reviewed.	0
CP032698.1|AYG81881.1|4496904_4498041_-|Cobalt-precorrin-5B-C(1)-methyltransferase	gnl|CDD|234615	PRK00075, cbiD, cobalt-precorrin-6A synthase; Reviewed.	5.68554e-157
CP032698.1|AYG81887.1|4507213_4508887_-|ECF-RNA-polymerase-sigma-E-factor	gnl|CDD|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	1.99638e-44
CP032698.1|AYG81888.1|4509067_4509901_-|Ubiquinone-biosynthesis-O-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	5.01374e-16
CP032698.1|AYG81877.1|4492623_4493517_-|Chitin-binding-protein-CbpD	gnl|CDD|376983	pfam03067, LPMO_10, Lytic polysaccharide mono-oxygenase, cellulose-degrading. This domain is found associated with a wide variety of cellulose binding domains. This is a family of two very closely related proteins that together act as both a C1- and a C4-oxidising lytic polysaccharide mono-oxygenase, degrading cellulose. This domain is also found in baculoviral spheroidins and spindolins, protein of unknown function.	1.60998e-58
CP032698.1|AYG81880.1|4495690_4496434_+|Precorrin-4-C(11)-methyltransferase	gnl|CDD|225430	COG2875, CobM, Precorrin-4 methylase [Coenzyme metabolism].	8.15824e-125

Protein sequences

>CP032698.1|AYG81878.1|4493649_4494072_-|Tetracycline-resistance-protein-TetO
MYEALRAGGPRGWAVADCAVTLVRSGFNSILSTAGDFRALTRIVLDLALREAGTLLYEPYQAFELEVPVASLASVTRQLTALGALIEEGGRAATGGSWRLCGTVAARRVAGIERRLPGLTHGEAAWWTRPADDRPLAGLA
>CP032698.1|AYG81877.1|4492623_4493517_-|Chitin-binding-protein-CbpD
MSPRRTAATVTTLAAASLTLLAVTPGAASAHGAVFNPVSRIAACFAEGPEHPVSQVCKDLVADSGTQPLYDWNEVNIANANGQSRQLIPDGKLCSANRDKYRALDWARTDWPSTSVSAGPFAFKFRATAAHSGTMTLYITKDGFDPTKPLKWSDLDSTPVAVYQTPRTATDGYYNFTGTLPTRTGRHIIYKVWQRNDSPEAFYSCSDVVYGGGAKAAAAAPTEQKMAAGAGRSTVSHHGHGGDPTAPTAPASSGAGSDSGSGSGSGSDHSAGPQALAAASTASVAGGGFLLLRRRRG
>CP032698.1|AYG81876.1|4492349_4492616_+|hypothetical-protein
MDLLPLRDFPACVDAVDPACPRCAADLTRARGDWRACPGCEYEMDADAVRLYQLLSAAYEAQPKEFFAWVERRRDRLRHEEPIWQRRR
>CP032698.1|AYG81875.1|4490045_4491983_+|hypothetical-protein
MGVSSSVKRMLVGRPLDTSRLGETLLPKRLALPIFCSDPLSSVAYATEEILLILALGGVGLLHLAWYAAAAIVFLLVVVIASYRQTCHAYPGGGGAYVVSAENLGPTAALTAASALLVDYVLTVAVSVVSGVAAITSAVPSLAPHQVALSVCFVVLLTVMNLRGVRESGRIFAIPTYGFVCVIYLMFAFAAVRLATGATIRAESADLPLHATGTYAGIAVVLLALRAFASGCTALTGVEAISNGVPAFQKPKSRNAANTLAAMGLLSVTMFVGITALAMTYRVHVAAVPTQLGLPAGATPSTALAQIARATFGNADLLFYLVQAFTAGVLVLAANTAFNGFPMLASILARDRYAPRQLYNRGDRLVYSNGVVLLALAAVALIVAFDAQLTRLIQLYIIGVFVSFTLSQAGMVKHWRKVLATPEGRDDRRRIHRSLAINAVGATLTGLVLVIVLITKFTHGAWLVVIAMPVLFFGMKGVRRHYDQVAREIAVGPDARPPRPSRHHAFVLVSRVQAPTLKAIGFAQALRPDTLTALTVAADEDAEGLREQWTAYDLGVPLTIIDSPYREVVGPVLAHVRETAEADSGAMVSVVIPEYIVGRWWEVPLHNQNALRLKARLLFMPGVTVIDVPYRLRSARQPVLNRRTG
>CP032698.1|AYG81874.1|4489046_4489877_-|hypothetical-protein
MTRPKDLNPWDSPRAFYGTELRRHREAAGLSQEELGALVFCSGTYIGQMESATRRPTKEMAKLLDAALHTDGILTRMCEAMEQASQHAEYFQLAAELESMASAIFHWTPMVVPGLLQTAAYTRALTRAGRPFATDEDVERNVSTRKERAKLLDGPEAPELWCILHEAALRIRVGDPGVMREQLAHIGELAQAGRIVVQVLPSEAGVLPLMHSSVKVMTFVDAPPVIYLEAARSGQLLDTPALVASYIKTYDLARAVALSPTASLAMIQAAMEDYAP
>CP032698.1|AYG81873.1|4488786_4489050_-|hypothetical-protein
MNITRSLAAARWRKSSYSNAEGGDCLEVAEGAWRKSSYSNDEGGDCVEVADGFGDVVPVRDSKVPSGPVLLVDATAWTRFVGAVKGV
>CP032698.1|AYG81872.1|4488525_4488762_-|hypothetical-protein
MAIPQLPPVVPASCPLCEGGLETVELRMTNAATAHLIAKFYRPEKMFASKSYVMASACRECGHVLMFLENRGILAPKG
>CP032698.1|AYG81871.1|4488047_4488515_+|hypothetical-protein
MSATVAMEMPVQVVEGPAKATNATEMPVLGLPTWYFPLVGLFAGLFDMAPAYPALYALIPVVAVVQIVLAFTVLRPRIRAMKALWKNKRTRFLAIGLVAVRFVIRYGLGMAGLALGAATGHLVLGIVMAAVGTAMAWGDQWLILRTLRRAQAPTV
>CP032698.1|AYG81870.1|4486262_4487891_+|putative-MFS-type-transporter-EfpA
MGRHTKDSVEVGRAERIAAASDGLAADGQPPPSTGAHPAAPPPPAAYTGEGGPPPQAPHTGARHEHRWLVLGVIALAQLMVVLDATIVNIALPSAQQDLGFSDGNRQWIVTAYALAFGSLLLLGGRIADLVGRKVVFLIGLVGFAVASAIGGAAPNFEVLVTARALQGVFGALLAPAALSLLTTTFTDPKERAKAFGIYGAVAGTGGAVGLLLGGILTEYLDWRWCLYVNLLFAALAFLGALRLLHPGAPSDRPKLDIPGTVLVSAGLFCIVYGFSNAETHAWSSPKTWGFLVVGGVLLIAFAWWQTRAKHPLLPLRVVLDRDRGASYLAMFISGAGMFGVFLFLTYYLQQILHYTPVKTGLAFLPMVFAMIVSSVVAQNKLVPRLGAKPIVPLGMGLGAAGLAWMTALDATSGYAGHVLPPLLVMGVGMGLIFAPAMSMATAGVAAHDAGVASAMVNTSQQVGGSIGTALLNTLATSAATSYLVGRQPTPGARVQAQLQSYSTAYWWSAAFFALGLVVSVILYRKGPPRQAVGPTEGPVHM
>CP032698.1|AYG81869.1|4485441_4486134_+|hypothetical-protein
MAGQRGRGVRNVRGWWLVLPVAALLVSGCTGGSGAGAESGSGSGSATGKPSAGASASAGVSPGPSASAGAYDPATYAPQVRTYAKKAGVSAQLLMAVLYNEDYKPHDPAFERSWQKYKPDAAFGIANMHRAAFDQTKRGRPFAARKWEELPDDRALAVEAAAWYLHDMSAQLPAHWAGGYSRDELMALGYNAGGGNMAAFARGAKPGSQASDYLTRLRDNWKKAGAAVAG
>CP032698.1|AYG81879.1|4494437_4495694_+|Precorrin-6Y-C(5,15)-methyltransferase-[decarboxylating]
MNPTPPTVTVVGLGADGWTGLTPAARHALTAAGVILGGPRQLALLPPECEGERIAWPTPLRPAVPGLLKAHAGHRIAVLASGDPMFYGIGRTLTEVLGAPPRILPHPSSVAYACARLGWAVEDVEVVTVVGRPLARVAAALHDGRRLIVLSAGADTPRDLAALLRERGFGPSCLRVLEQLGSGEENEVAGTADGWGAAPGDPLNVVAVDCRRAPDALRLGAVPGLPDTAYEHDGQLTKRHIRAATLGALAPAPGELLWDIGGGSGSIAVEWMRTHPSCQAFTVERDPVRAERIARNADRLGVPGLRVVTGAAPAALAQLTTPDAVFIGGGLTAPGLLDACWDALPAGGRLVANTVTLESEALLADWYRRHGGELVRLTVAHAVPVGTFTGWRQAMPVTQWAVVKGGPLNPNSPSGDAI
>CP032698.1|AYG81880.1|4495690_4496434_+|Precorrin-4-C(11)-methyltransferase
MTVYFIGAGPGAADLITVRGARTLASCQVCLYAGSLVPRELLAECPEGARLVDTAQLNLDEITGELVRAHEAGLDVARLHSGDPSVFSAVAEQMRRLDAAGVPYEVVPGVPAFAAAAAALKRELTVPTVGQTVILTRVAQRATAMPEGEDLATLGRSGALLVLHLAAGYVDRVVEELLPHYGADCPAAVVAFASRPEELILRGTLSDIAGQVKGAGVVRTAVILVGRTLGAAGFRDSHLYSAERHRC
>CP032698.1|AYG81881.1|4496904_4498041_-|Cobalt-precorrin-5B-C(1)-methyltransferase
MSEAKGGRGAQLKHTGLRSGWTTGACATAATTAAYTALLSGDFPDPVTITLPRGQTPAFALAAEELGAEEPGAGWAMAAVVKDAGDDPDVTHGALIRSTVRLLPPGSGVVFRAGEGVGTITLPGLPLPVGEPAINPVPRQMMTEHVTRVAAEHGASADVEITISVDHGAEIARSTWNPRLGILGGLSILGTTGIVVPYSCSAWIDSIRRGVDVARAAGRTHVAGCTGSTSEKTVVAEYGLPEDALLDMGDFAGAVLKYVRRHPVDRLTICGGFAKLSKLAAGHLDLHSARSQVDKAFLAALAREGGASEALAAQVSTANTGLAALELCTAAGVPLGDLVATRARDEALAVLRGAPVAVDVLCIDRAGTVVGRTTPTGP
>CP032698.1|AYG81882.1|4498128_4498887_+|Precorrin-6A-reductase
MHILILGGTGEARRLAGLLHEAQGPAVRVTSSLAGRVAEPRLPPGEVRVGGFGGAEGLARWLRTHQVDALIDATHPFARTISFNAAHAATAAHVPLLALRRPGWVPGEGDRWHPADSLDEAAALLPALGRRVFLTTGRMGLAAFAGLDALWFLMRSVDAPEPPYPARMEVLLDRGPFTLEGEREVLRTHRIDVLVTKDSGGAATAPKLTAAREAGIPVVVVRRPPVPDGVSVAATPEEAAAWVGHWVGQLSG
>CP032698.1|AYG81883.1|4498871_4500458_-|Cobalamin-biosynthesis-protein-CobIJ
MNESAMNDENSDETGGGAAVGRLYGVGLGPGDPSLMTVRAVEAIAQADVVAYHSARHGRSIARSIAAKHIRADHIEEKLVYPLTVETTDHPGGYRGALNDFYEEASARLAEHLDAGRTVAVLAEGDPLFYGSYQHMHKRLAHRYPTEVIPGVTSVSAAAARLGEPLVEAEEVLTILPGTLPEEELTARLAATDSAVVMKLGRTFTKVRRALERSGRLEEARYVERATMAGERTGHLADVDPESVPYFSVAVLPSRIDAVPPVRERGEVVVVGTGPAGPLWLTPESRGALAAADDIVGYTTYVDRVPERPGQQRHGSDNKVESERAEFALQLAMRGRRVAVVSGGDPGIFAMATAVLEVASQPEYAQVPVRVLPGVTAANAAAARAGAPLGHDYATISLSDRLKPWDVIAERLHAAASADLVLALYNPGSASRTWQVAKARELLLEHRAPETPVVVARDVGGPGERVRIVRLGDLDPAEVDMRTILLVGSSQTQVVRRGSGDGGGDCAVGGDCAVGEEIVWTPRRYPES
>CP032698.1|AYG81884.1|4500454_4501123_-|Precorrin-8X-methylmutase
MTTPGDNDEMSESTVFDYEKDGAEIYRQSFATIRAEADLTGLPADVSQVAVRMIHACGMTDLPRDLGFTPGVVARAREALRAGAPILCDARMVASGVTRKRLPADNEVLCTLADPSVAELAAKMGTTRSAAALELWRDRLDGAVVAVGNAPTALFRLLEMIEEGAPRPAAVIGVPVGFIGAAESKDALAAHPSGLEHLVVRGRRGGSAIAAAALNAIASEAE
>CP032698.1|AYG81885.1|4501119_4502469_-|hypothetical-protein
MLAAMPPPPTPTTPQQGEPATPAAPNPPTPAALPPTRDRDDACPGALRLHAADDGRLARLRLPGGILTNRQVGALAAAAERYGDGHLTITSRGNAELRGIGESCGTGLAELLRHTHLLPSERHERVRNIVASPLAGLDGLGHGTLLPRLRALDALLCAEEWTAALSGRFLFALDDGRGDIAGLGADVTLLAQERDTVAVRVGESAVEVAASDAPRAALEAARAFLATAAAAGTGAWRVRDLPPGHTVDLTTALAQANIPAAPTSVTPPPTPKPVSTPTPGVVAGPDGTYTVVVTPVLGRVTAAQLRALAGPGGEVRVTPWRGFVVPGFDERGARERLRELGDAGFVTAPDAPWAGVGACTGRPGCAKALADVRRDALSGTGGLPVHWSGCERRCGHPHGDWVDVTATADGVYTLAVRGARERQVPLEEGELAQAVAAARRAPQAPPRTI
>CP032698.1|AYG81886.1|4503441_4507149_+|Aerobic-cobaltochelatase-subunit-CobN
MLHSSGEPVEDPRPILLLSTSDTDLLSARAANGPVPYRFANPSRLALSPLNTPPTGASQDAQGAPRDPDLLDALLDGVGLVVVRLLGGVRAWQDGLDRLTASGLPVVVLTGEQAPDAQLMAASTVPVGIAAEAHAYLAHGGPANLDQLARFLSDTVLLTGHGFEPPAPAPSWGPLERTGKAVQGPTVAVLYYRAHHMSGNTAFVDTLCGAIEDAGGRPLPLYVSSLRDPEPALIEELRAADAIVTTVLAAGGTKPATASAGGDDESWDAGALSGLDVPILQALCLTGSRTAWEENDEGVSPLDAASQIAVPEFDGRLITVPFSFKEIDEDGLPSYVADAERSARVAGIAVRHAKLRHIAAADKRLALVLSAYPTKHSRIGNAVGLDTPASAVALLRRLRAEGYDFGPEEEIPGLVSGDGDELIRALIDAGGHDQEWLTEEQLAANPVRIPAADYKRWYATLPEELRENVERHWGPPPGEMFLDRSRVGNGGDPEGDIVLAALRRGNLLILIQPPRGFGENPIAIYHDPDLPPSHHYLAAYRWIAASAADGGFGADAMIHLGKHGNLEWLPGKNAGLSAACGPDAALGDLPLVYPFLVNDPGEGTQAKRRVHATLIDHLVPPMARADSYGDIARLEQLLDEHAQIAAMDPAKLPAIRAQIWTLIQAAKLDHDLGLEDRPEDEGFDEFIMHLDGWLCEIKDVQIRDGLHVLGNAPAGADRVNLVLAILRARQIWGGTTALPGLREALGLDESAATRTSADEAEEQARALVQLMDDAGWDLAAIPADQPQQVRAILEFAAREVVPRLAATTAELDHTVHALNGGFVPAGPSGSPLRGLVNVLPTGRNFYSVDPKAVPSRLAWETGQALAESLAGRYRADNGDWPTSVGLSLWGTSAMRTAGDDVAEAMALLGVRPVWDDASRRVTGLEPIPLDELGRPRIDVTLRISGFFRDAFPHTIGLLDDAVRLAASLDEPADVNYVRAHTQADLAEHGDERRATTRIFGSRPGTYGAGLLQLIDSRDWRTDADLAEVYTVWGGYAYGRELDGRPARDEMETAYKRIAVAAKNTDTREHDIADSDDYFQYHGGMVATVRALRGTAPEAYIGDSTRPETVKTRTLVEETSRVFRARVVNPKWIEAMRRHGYKGAFELAATVDYLFGYDATTGVVADWMYDKLTETYVLDPANREFLQNANPWALHGIAERLLEAESRGMWAKPDPAVLEALRQVYLETEGDLEDEG
>CP032698.1|AYG81887.1|4507213_4508887_-|ECF-RNA-polymerase-sigma-E-factor
MISEQVAAVVVAARAGDQRARDELVAGYLPLVYNIVGRALDGHADVDDVVQESLLRMLDGLGSLREPEAFRSWLVAVTMNEIRRYWQGHRRATVTGGLQDAHDVADPGADFVDLTIVRLGLSGQRKEVTEATRWLETDDRALLSLWWLEAAGVLTRGEVASALDLSAEHAAVRVQRMKGQLETARVVVRALAGIERCGELSGLALSWDGVPSALWRKRIARHARTCAVCSGHWSGLIPAEGLLVGLALVPVAGASAGLLAALHGADPALQSAAHATATASTQPMTAAQTAPRAAHGSHAAGRRRAPASRRDRRDQRARRRRRGAAVIAALAAVATLGGAYHFMTDAGQAPSRSVADAPATLTDAAAADGSTRPLPPTPSATNSPKAPTSSPSPSPSKSSASPTKSAARPTPPKATPSTRRATPRTVDTSVPADVQQVLDLVNSERAKAGCSALTTNSKLYEAALKHSENMAAQNFFDHTDPSGAGPGERITAAGYRWSTYGENIARGQADAAAVMDSWMHSSGHRANILNCAFKEIGIGVHHGSGGPWWTQDFGTQS
>CP032698.1|AYG81888.1|4509067_4509901_-|Ubiquinone-biosynthesis-O-methyltransferase
MTSDPVVAPEVLAFYTETTDESVRLTSSADGALELIRTQEILRRYLPAAPADVLDVGGGPGIHAKWLAEDGYTVHIVDPVHRHVEQVPDGVTAEVGDARKLPASDHSQDVVLLLGPLYHLLEREERDRALAEALRVVKPGGLIAAAAIGRYASLFEHVATTLLDVERVHDAVADILVNGRHEPGRKGFTAAYFHTAASLAEELTEAGVADVRVIGIEGPSWGALKAAETHSEESLRDSAMFRAALAAARLAEPYPDLLSASSHMLAVGRAPGCPGGA

Crispr_ID: CP032698_49

• CRISPR_ID: CP032698_49
• CRISPR_location: 4596238-4596318
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_49

Consensus_repeat	Method
GTCGCGCAGTTCCCCGCGCCCCT	CRISPRCasFinder

spacers of CP032698_49

>49.1|4596261|35|CP032698|CRISPRCasFinder
AAAAGCCCTCGGTCGTGTGCGGACCGTGCCCGCGT

CRISPR arrays and Neighbor proteins around CP032698_49

CRISPR arrays

The CRISPR arrays of CP032698_49

>merge|CP032698|49|4596238-4596318|CRISPRCasFinder
GTCGCGCAGTTCCCCGCGCCCCTAAAAGCCCTCGGTCGTGTGCGGACCGTGCCCGCGTCTCGCGCAGTTCCCCGCGCCCCT

>CP032698|49|38|4596238-4596318|CRISPRCasFinder
GTCGCGCAGTTCCCCGCGCCCCT	AAAAGCCCTCGGTCGTGTGCGGACCGTGCCCGCGT
CTCGCGCAGTTCCCCGCGCCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81962.1|4588816_4589341_+|hypothetical-protein	unknown	unknown	gnl|CDD|378512
CP032698.1|AYG81972.1|4599954_4600815_+|Tryptophan-2,3-dioxygenase	unknown	unknown	gnl|CDD|188272
CP032698.1|AYG81977.1|4604680_4606090_+|Sensor-histidine-kinase-LiaS	unknown	unknown	gnl|CDD|226951
CP032698.1|AYG81961.1|4587971_4588814_-|hypothetical-protein	unknown	unknown	gnl|CDD|367272
CP032698.1|AYG81978.1|4606086_4606752_+|Response-regulator-protein-VraR	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG81975.1|4603311_4603881_-|hypothetical-protein	unknown	unknown	gnl|CDD|379115
CP032698.1|AYG81971.1|4598775_4599852_+|hypothetical-protein	unknown	unknown	gnl|CDD|371483
CP032698.1|AYG81964.1|4591184_4592120_+|hypothetical-protein	unknown	unknown	gnl|CDD|176865
CP032698.1|AYG81968.1|4595016_4596165_+|Cystathionine-beta-lyase-PatB	unknown	unknown	gnl|CDD|224090
CP032698.1|AYG81976.1|4604034_4604580_+|hypothetical-protein	unknown	unknown	gnl|CDD|379860
CP032698.1|AYG81973.1|4600807_4601998_+|Kynureninase	unknown	unknown	gnl|CDD|226363
CP032698.1|AYG81970.1|4598183_4598597_+|hypothetical-protein	unknown	unknown	gnl|CDD|378646
CP032698.1|AYG81969.1|4596503_4597994_+|Multidrug-resistance-protein-Stp	unknown	unknown	gnl|CDD|129794
CP032698.1|AYG81966.1|4593067_4593616_+|Orotate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234771
CP032698.1|AYG81967.1|4593878_4594901_+|Fructose-bisphosphate-aldolase	unknown	unknown	gnl|CDD|236406
CP032698.1|AYG81963.1|4589425_4591051_+|Polyamine-aminopropyltransferase	unknown	unknown	gnl|CDD|235139
CP032698.1|AYG81965.1|4592200_4592989_+|hypothetical-protein	unknown	unknown	gnl|CDD|185698
CP032698.1|AYG81960.1|4586769_4587975_-|putative-N-succinyldiaminopimelate-aminotransferase-DapC	unknown	unknown	gnl|CDD|236095
CP032698.1|AYG81974.1|4602092_4602980_+|hypothetical-protein	unknown	unknown	gnl|CDD|223730
CP032698.1|AYG81959.1|4585416_4586478_-|hypothetical-protein	unknown	unknown	gnl|CDD|379080

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81962.1|4588816_4589341_+|hypothetical-protein	gnl|CDD|378512	pfam10936, DUF2617, Protein of unknown function DUF2617. This bacterial family of proteins has no known function.	6.88585e-66
CP032698.1|AYG81972.1|4599954_4600815_+|Tryptophan-2,3-dioxygenase	gnl|CDD|188272	TIGR03036, trp_2_3_diox, tryptophan 2,3-dioxygenase. Members of this family are tryptophan 2,3-dioxygenase, as confirmed by several experimental characterizations, and by conserved operon structure for many of the other members. This enzyme represents the first of a two-step degradation to L-kynurenine, and a three-step pathway (via kynurenine) to anthranilate plus alanine. [Energy metabolism, Amino acids and amines].	6.69427e-148
CP032698.1|AYG81977.1|4604680_4606090_+|Sensor-histidine-kinase-LiaS	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.19031e-34
CP032698.1|AYG81961.1|4587971_4588814_-|hypothetical-protein	gnl|CDD|367272	pfam02956, TT_ORF1, TT viral orf 1. TT virus (TTV), isolated initially from a Japanese patient with hepatitis of unknown aetiology, has since been found to infect both healthy and diseased individuals and numerous prevalence studies have raised questions about its role in unexplained hepatitis. ORF1 is a large 750 residue protein. The N-terminal half of this protein corresponds to the capsid protein.	3.22837e-06
CP032698.1|AYG81978.1|4606086_4606752_+|Response-regulator-protein-VraR	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.7593e-76
CP032698.1|AYG81975.1|4603311_4603881_-|hypothetical-protein	gnl|CDD|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	2.19165e-20
CP032698.1|AYG81971.1|4598775_4599852_+|hypothetical-protein	gnl|CDD|371483	pfam11350, DUF3152, Protein of unknown function (DUF3152). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	3.29175e-34
CP032698.1|AYG81964.1|4591184_4592120_+|hypothetical-protein	gnl|CDD|176865	cd07823, SRPBCC_5, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	4.63498e-20
CP032698.1|AYG81968.1|4595016_4596165_+|Cystathionine-beta-lyase-PatB	gnl|CDD|224090	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism].	1.59739e-137
CP032698.1|AYG81976.1|4604034_4604580_+|hypothetical-protein	gnl|CDD|379860	pfam16571, FBP_C, FBP C-terminal treble-clef zinc-finger. FBP_C is a family from the C terminal end of fibronectin-binding proteins. It forms an extended four-cysteine zinc-finger with a unique structural fold. Fibronectin-binding proteins bind to elongation factor G - EF-G, which is mediated by the zinc-finger binding to the C-terminus of EF-G. FBPs release ribosomes by competing with them for EF-G.	8.56484e-89
CP032698.1|AYG81973.1|4600807_4601998_+|Kynureninase	gnl|CDD|226363	COG3844, COG3844, Kynureninase [Amino acid transport and metabolism].	2.49805e-144
CP032698.1|AYG81970.1|4598183_4598597_+|hypothetical-protein	gnl|CDD|378646	pfam11349, DUF3151, Protein of unknown function (DUF3151). This family of proteins with unknown function appears to be restricted to Actinobacteria.	4.27641e-73
CP032698.1|AYG81969.1|4596503_4597994_+|Multidrug-resistance-protein-Stp	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.26691e-76
CP032698.1|AYG81966.1|4593067_4593616_+|Orotate-phosphoribosyltransferase	gnl|CDD|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	9.75614e-61
CP032698.1|AYG81967.1|4593878_4594901_+|Fructose-bisphosphate-aldolase	gnl|CDD|236406	PRK09197, PRK09197, fructose-bisphosphate aldolase; Provisional.	0
CP032698.1|AYG81963.1|4589425_4591051_+|Polyamine-aminopropyltransferase	gnl|CDD|235139	PRK03612, PRK03612, polyamine aminopropyltransferase.	0
CP032698.1|AYG81965.1|4592200_4592989_+|hypothetical-protein	gnl|CDD|185698	cd09021, Aldose_epim_Ec_YphB, aldose 1-epimerase, similar to Escherichia coli YphB. Proteins similar to Escherichia coli YphB are uncharacterized members of the aldose-1-epimerase superfamily. Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism, catalyzing the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family, galactose mutarotase, have shown a glutamate and a histidine residue to be critical for catalysis; the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen.	1.29445e-59
CP032698.1|AYG81960.1|4586769_4587975_-|putative-N-succinyldiaminopimelate-aminotransferase-DapC	gnl|CDD|236095	PRK07777, PRK07777, putative succinyldiaminopimelate transaminase DapC.	0
CP032698.1|AYG81974.1|4602092_4602980_+|hypothetical-protein	gnl|CDD|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	9.55228e-13
CP032698.1|AYG81959.1|4585416_4586478_-|hypothetical-protein	gnl|CDD|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	0.00179009

Protein sequences

>CP032698.1|AYG81968.1|4595016_4596165_+|Cystathionine-beta-lyase-PatB
MTTYDFDTPVDRRGTWSIQWDGAAERFGADGLLPFTISDMDFRCPPPVLAALQERVAHGVFGYTDWQNEEFRSAVRDWYRDRHDTELDTTRLVYAPSVLSQLSQLLRMWTEPGDAVVVHTPVYDGFRRTVTGLGRELREVPLDDPAALDAALAGPRARVLLLCSPHNPTGRVWTEAELTSFASLAQRYGAAVISDEIHADFVHAGRRHLPWSRFGQGRWALITSGTKAFNFPSLTGSYGILGDAADHAEFVRRMQTGEGLGSPAVLSLTAHIAAYREGAGWLDAVRAYVAGNLALVASTLNSAFPELSWAPPQAGYLAWIDLRALGVEEGALQRELVEGERVAVMPGGVYGAPGFVRLNVGCARGKVGVGVAALVRALGRLT
>CP032698.1|AYG81967.1|4593878_4594901_+|Fructose-bisphosphate-aldolase
MPIATPEVYNEMLDRAKAGKFAYPAINVTSTQTLHAALRGFAEAESDGIIQISTGGAEFLGGQYNKDMVTGAVALAEFAHVVAAKYDITVALHTDHCPKDKLDGYVRPLLEVSAERVARGLNPLFQSHMWDGSAETLADNLAIGQELLAKAAAAKIILEVEITPTGGEEDGVSHEINDELYTTVDDALRTAEALGLGEKGRYLLAASFGNVHGVYKPGNVVLRPELLKDLQAGVAEKYGKPSPFDFVFHGGSGSSAEEIATALENGVVKMNLDTDTQYAFTRPVADHMFRNYDGVLKVDGEVGKKSTYDPRTWGKLAEAGMAKRVTEACANLRSTGTKLK
>CP032698.1|AYG81966.1|4593067_4593616_+|Orotate-phosphoribosyltransferase
MTDVRADLLQQIKDKAVVHGKVTLSSGIEADYYVDLRRVTLDGVAAPLVGQVMLDITAAFDFDAVGGLTMGADPVAGAMLHAAAARGRTLDAFVVRKAAKAHGMQRQVEGPDIKGRRVLVVEDTSTTGGSPLTAVEAVRAAGAEVVAVATIVDRATGAAEKITEGAGVPYVFAFSSEELGLA
>CP032698.1|AYG81965.1|4592200_4592989_+|hypothetical-protein
MSSDQIKLGVGAAELTVDAGNGCRISSLVIDGTEVLRQGDKYGCFPMVPWCGRVENGQFRDGGVKHQLPLNSPPHAIHGTGRDHAWHTARVSDTEAVFTYELAEPWPYTGRVTQIFELTPDALTVRMGVETYDNSFPAQVGWHPWFVREIDGSRVGLAFDAAWQEERGDDHLPTGRRIEPLPGPWDDCFGMPDGVDVTLTWPGRLELKVTSPGEWVVIYDEQAEAVCVEPQSGPPNGLNTLPRLVTPIEPLELATTWSWRRL
>CP032698.1|AYG81964.1|4591184_4592120_+|hypothetical-protein
MEHEVFVPVESHSLRQTLRDPARVARCVPGFQQDAGEPPIAGRLKVRLGGHTITYRGALRVTERDGDVFALEGEGVEVRGAGAAKLTLTVRLEAAPGGTTLAFAGTALAEGRATEVPQEAVNASAVRLLDRFAAQLAHPARTEQPEAADLAAAAEDPTAPPDAADTDLNTDLDPEGPARRRPAPGPVGQDPDLDAAPGPGPVPDAELGAILGDEDLASVFDAEVPPPSLDPLADDEFAIEVGAPAEAAHARRTMIGRSAEEVDHAPPRGRYAPVPAPSGSNAGATLRWAAPAAALALASAVVVGRALRRRR
>CP032698.1|AYG81963.1|4589425_4591051_+|Polyamine-aminopropyltransferase
MIEPLPAPVSSARSGRFLVLAVVFVCAACGLVYELELVALASYLIGDSVTQASVVLSVMVFAMGVGSLLAKRLRCRAAVGFGLIEAALALVGGCSAIVLYATFAWFGGSRYALVAFSLAIGILIGAEIPLLMTLIQRVSRRAAGDASGTVADLFAADYVGALVGGLAFPFLLLPQLGQLTSALLTGSVNAVAGGALVLLLFGRDLSPRARWALLGANALVLLVLALTTVMVDDFEQAARRAVYGGQVRVAVQTRVQEIVLTGKAGAPLDLFLDGRLRINGLDESRYHAALVGPALDAGPHGRVLILGGGDGLAAREVLRHRDVRSVTLVERDPGLLQLARDDPRLAALNAHALRDPRLRPVTGDAFGWLRGEGRLSGPYDVVVSDLPDPGITASTKLYSQEFYGLARRVLAPGGRLVVHAGPVAGRPRTFWTVASTVRAAGLTTFAYRATGRSAGFTAGPDRALGSAKSPHDWGFVLAARPAPHPFAAGAAPDRPGAEDRAGAGTWAAAGVRLPAGSLALTPPSEAAGYPPSTLVHPRYAD
>CP032698.1|AYG81962.1|4588816_4589341_+|hypothetical-protein
MLTTLQTAYTDTRAADLAWALGREPLPALAVLDLELDGAKLQLRLLGASHQVLLDEERGTCSETVACMPGSSTPLPLGVAKRLGDWDYEFAARVETLSQGSFAGRAQELLALVADHPNGLAGTFPGSPHAFTAMLAQRVEGQVWWRTWHAYPQEGQLVVTRTRVGVRVAATAGL
>CP032698.1|AYG81961.1|4587971_4588814_-|hypothetical-protein
MGSAKHTCGGWVTEVPSEARDGGRSLIARGPRCVVSHLRGNHEVRGAHSFFTQLDGVSIPSGATRFKRSTTGVKEGARPGVTDRAPTGGARGGIGCPVSAATARRPPPVALDDPPPGPSGRVGPSGSLSSNRSLPLPRTRSRRRRRSGCRPRRSARRRRSARGRPRGRGGRRFRFRTTRSIRPIRRPTSWTFPRTTPRPVAGATPGRGARAHAVACAPPVRPRHPARSVPGSPPRSRCPSPTVLPWCGSPVGPRGRGMPLATRRQSTLEQLQRLPAGWPS
>CP032698.1|AYG81960.1|4586769_4587975_-|putative-N-succinyldiaminopimelate-aminotransferase-DapC
MTSSARPLLNRRLAEFGTTIFAEMSALAQRTGSINLGQGFPDTDGPEAVREAAVRALREGHGNQYPPGPGVPELRTAIVEHQRRRYGLSYDPDQEVLVTAGATEAIAAALLALLEPGDEVIALEPYYDSYAACIAMAGGTRVPVTLRPAAAPGGESGQGHFALDLDELRAAVTPRTRLILLNTPHNPTGTVLTRAELAAVAELACERDLLVITDEVYEHLVFDGAEHIPLASFPGMRERTVTIGSAGKTFSFTGWKVGWITAAPGLVAAVRSAKQFLTYVTSGPFQYAVAEALRLPDSYFDGFRADHQAKRDLLSAGLAKAGFGVFRPAGTYFVTTDIRPLGVSDGFAFCRALPERCGVVAIPNAVFYDHRDQGAPFVRFAFCKRTAVLEEAVARLTSLAA
>CP032698.1|AYG81959.1|4585416_4586478_-|hypothetical-protein
MRLTGLLVFAALAWHRGLSPRARLATAWDADWYTRIAAHGYGRTLFWPDGAVQSDLAFFPLYPALIRAVTVVLPVTGGTAGLLLSWTAAAAAAWGIHRIGERLYGRPVATLLVLLWGLLPHAVVLTMAYTEPVMTALAAWSLWAVLERRWLWAGSLALLAGLARPNAVAVAAAVLVAAGHALWRGEGRSWRPWAGGLLAPVGWCGYVLWVGVREGDLFGGYFAVQAGWTSRFDFGAGTLRFLKRLASAPYDLGFPMAALITAAMVLLFVLFVLDRPALPLLVYTGVLVVIAVGGAGFFESKPRFLLPAFPLLAPVALALTRARPRAAVAVTAALAGLSFCYGAYLLTLATMAL
>CP032698.1|AYG81969.1|4596503_4597994_+|Multidrug-resistance-protein-Stp
MGDRWAVADNVRMGTRPARWVLLTTVLGSGMALLDSTVVNVALPHIGTDLDADMAVLQWTVNAYMLTLAGLILLGGALGDRYGRRKVFVIGVVWFAAGSLLCGVAPTAGVLIAARALQGIGGALLTPGSLAIIQSGFHPDDRARAVGVWSGLGGVGAAVGPFLGGWLVDGPGWRWVFLINVPLAALCVAVALGHVPETRDPRVHTGRFDAAGAALGALALALVTYALIEAPGQGSSGVVVGAGVAGLGLGVVFVRRERRLPDPMLPPAIFRSRIFTAVNCVTVCVYAAFGGFFFLAALQLQVVAGYSALGAGAALLPTTVLMLLLSARSGELGRRIGPRVPLTVGPLLCAAGMLLMLRVGEHAAYVSDVLPALVVLGLGMVTLVAPLTATVLASVDEGRAGLASGINNAAARAAGLLAVAALPLAAGMGPEAYRSAAEFGATFRRAMPMCAGALVLASGVAFFAVRRAGRGVVPECRMQCGVSAPALEPNPNPSTP
>CP032698.1|AYG81970.1|4598183_4598597_+|hypothetical-protein
MSLHENLLGGPAPTLLPDDPEPRDLLAQGTAPADVAAKYPTSSLAWAQLADDAFDGGRTVESYAYARTGYHRGLDSLRRAGWKGHGPVPWEHEPNRGFLRALHALARAAQAIGEDAEYERCTTFLRDSSELAAETLG
>CP032698.1|AYG81971.1|4598775_4599852_+|hypothetical-protein
MGKRGARSTTKRTGRTDQTGRASRFSQTGRASRLSQTGRAGEPGRTSRSRTARTTSNSTTSNSTTSNSTTSNSTTSNSTTSTATTSALTTPRSRTLLVVAALLGTTLLGGVALAQWPGGHGKAVEAGNTVASPMEEQSPRPVEPSPPPTPAKASGDPGRPADPGTPEEPSVPPSGPGTFTAARAAGKVVGTGGPLRRYQVQVEDGAGVSATQAAVDVQAILSDGRSWAAHGKGRFQLVADGADVVIKIATPKTTDKLCASVGDTGGELNCEVAGGVVVNLKRWAKGSPQYAGPPAEYRHLIINHEIGHLIGYHQHMGCPGPGRAAPVMMQQIKGLDGCTSNAWPYTAQGTFVTGPPAP
>CP032698.1|AYG81972.1|4599954_4600815_+|Tryptophan-2,3-dioxygenase
MSSKMSEPVTPPEGGDAPETPNLDFAGTTPYEDYVQADVLTHLQHLRSDDPGEMVFLVTTQVMELWFTVIVHEWETASRALREDRVPVAVDALKRSVRELEALNASWTPLAQLTPAQFNSYRSALGEGSGFQSAMYRRMEFLLGDKSASMLVPHRGAPRVHAELEKALGEPSLYDEVLALLARRGHAVPASVLQRDLTRKYEPSPEVEAVWAELYAGDQNGELVRLGEALTDVGELVWRWRNDHLVATRRAMGAKAGTGGSAGVAWLEKRATKNVFPELWTARSHV
>CP032698.1|AYG81973.1|4600807_4601998_+|Kynureninase
MSEALAGQAAALDAADELAACRALFALDDDVVYLDGNSLGALPRHVPARMQDVIAREWGQLRIRSWEESGWWTAPERIGDRIAPLVGADRGTVVVGDSTSVNVFKALVGAVRLAGDDRDEILVDASTFPTDGYVAESAARMTGRRIRALAPQEIVGALGPRTAAVLVNHVDYRSGRLNDLPAMTAAIHAAGALAVWDLCHSAGALPVGVGAHGVDFAVGCTYKYLNGGPGSPAYLYVRGDHQARFDTPLPGWNSHEDPFGMRSAYAPGDGAVRGRVGTPDILSMLALESALDVWDGVSIDAVRAKSLALTDFFLECVEAYVPAGRVSSVTPAAHAERGSQVSLSCEKAGEVMRALIERGVVGDYRRPDVLRFGFTPLYVGFADAERAAGELAALLD
>CP032698.1|AYG81974.1|4602092_4602980_+|hypothetical-protein
MDPAERDAVEEASVFSHPPVAPDATAAYGDHPDQVIDFYAPRGARAGAPLVALLHGGAWRATYDRAHMTPFADFLARRGFAVANIEYRRGTLLPRQGDGSGAPATGQPVAGRWPDTFDDVAAAVDALPLLVRDAVPGADPRRTVLTGHSAGGHLALWAAARHVLPEGSPWRTPAPAPLRGVVALAPIADFATAVDLAVCSDAVAQLLGGPPQLGLRFPHADPSALLPTGIATAVVQGREDIVVPRAVAEAYVGAAARAGEVVGLTLLDEVGHFPLIDPAADACAVVADELAQLAY
>CP032698.1|AYG81975.1|4603311_4603881_-|hypothetical-protein
MARVGLTTDRLVRAGAELADEVGFEQVTVSALARRFDVKVASLYSHVKNSQDLKTRLALLALEELADQAADAVAGRSGKDALAALGNVYRDYAREHPGRYAAAQLRLDPEAAAASAGRRHSQMTRAILRGYDLPEREEVHAVRLLGSVFHGYISLEMGGGFSHSAPDTQETWERTLSALDTLLRTWPTP
>CP032698.1|AYG81976.1|4604034_4604580_+|hypothetical-protein
MKPLTEQDIRASFVNCTKGEAKRLSVPRDLAERPWDDLDYLGWRDPQAPDRGYLVVELDGRPHGLALRCSSALWGRQRRSMCSMCLTTHSGGVSLMVAPKAGKAGKQGNSVGAYICADLDCSLYVRGKKDAGIGARLHETLTVEEKIERTVLNVAAFVAKVTGSPDAPVAPEAMGTPSPTA
>CP032698.1|AYG81977.1|4604680_4606090_+|Sensor-histidine-kinase-LiaS
MVDVNETTTSPRQGSGSSTVAGGGAAERTPEFRLAMDAYGGLCKDLLHDAFAYRPLPPMRTDGVITRRLPGRIREAAAWTPHAVVCFFAFLAMLFGYTGSLSGIGGGLAFMLSGLFVAVPVIVTLVRPIGAFWLSCAAIVITGLMGYHGSMTPWTPGSVFMHLTVLVVVALRTRPRVALGMWGVTFALGVMVGVVRGRSDAFGTGVQMAIFYGMVLLVISVVHIRKDAERQVSAEKSVTAVERDRRTVLEERTNIARELHDVVAHHMSVVAIQAEAAPYRVENPPPELAQAFATIRENAVSALTELRRVLGVVRAEDYEAPDAPQPTLADLDGLLANVREAGLDVEKVVTGAVRELPQGVELSAYRIIQEALSNTLRHAPGAAARVEIGYVLGGLGLRVINGRPTTEAGPSQGSGHGITGMAERVAMLGGAMTAERTAEGGYEVTVFIPVAPAEPESTVDLAKGTDERA
>CP032698.1|AYG81978.1|4606086_4606752_+|Response-regulator-protein-VraR
MTIRVLIVDDQMMVREGFSVLLGAQPDIEVVGEAVDGREAVAQVRALRPDVVLMDIRMPGMNGIEATREIVASDDSSKVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPSVTRRLINEFARVVPVARGGSSPTGQVEELTDRETEVLVLIAQGLSNQEIADRLVVAESTIKTHVSRVLVKLGLRDRTQAAVYAYETRLVTPS

Crispr_ID: CP032698_50

• CRISPR_ID: CP032698_50
• CRISPR_location: 4603108-4603263
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_50

Consensus_repeat	Method
AGGGGGTTCAGGGGCGCGGGGAACTGCGCGAAAAGCGAGCACGGTC	PILER-CR

spacers of CP032698_50

>50.1|4603161|21|CP032698|PILER-CR
CCAGCCCCCCACGGCCCGCAG
>50.2|4603235|10|CP032698|PILER-CR
CGCAGAATCG

CRISPR arrays and Neighbor proteins around CP032698_50

CRISPR arrays

The CRISPR arrays of CP032698_50

>merge|CP032698|50|4603108-4603263|PILER-CR
GTTAAGGGGCGCGGGGAACTGCGCGACCAGCCCCCCACGGCCCGCAGCCGAAAACGGGTTTCCAGGGGCGCGAGGAACTGCGCAAAAAGCGAGCACGGTCCGCAGAATCGAGGGGGTTCAGGGGCGCGGGGAACTGCGCGAGAAGCGAGCACGGTC

>CP032698|50|14|4603108-4603263|PILER-CR
GTTAAGGGGCGCGGGGAACTGCGCGACCAGCCCCCCACGGCCCGCAGCCGAAA	ACGGGTTTCCAGGGGCGCGAG
GAACTGCGCAAAAAGCGAGCACGGTCCGCAGAATCGAGGGGGTTCAGGGGCGC	GGGGAACTGC
GCGAGAAGCGAGCACGGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG81972.1|4599954_4600815_+|Tryptophan-2,3-dioxygenase	unknown	unknown	gnl|CDD|188272
CP032698.1|AYG81977.1|4604680_4606090_+|Sensor-histidine-kinase-LiaS	unknown	unknown	gnl|CDD|226951
CP032698.1|AYG81978.1|4606086_4606752_+|Response-regulator-protein-VraR	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG81979.1|4607249_4608476_+|Polyketide-biosynthesis-cytochrome-P450-PksS	unknown	unknown	gnl|CDD|225035
CP032698.1|AYG81971.1|4598775_4599852_+|hypothetical-protein	unknown	unknown	gnl|CDD|371483
CP032698.1|AYG81970.1|4598183_4598597_+|hypothetical-protein	unknown	unknown	gnl|CDD|378646
CP032698.1|AYG81983.1|4612862_4613798_-|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|223656
CP032698.1|AYG81968.1|4595016_4596165_+|Cystathionine-beta-lyase-PatB	unknown	unknown	gnl|CDD|224090
CP032698.1|AYG81976.1|4604034_4604580_+|hypothetical-protein	unknown	unknown	gnl|CDD|379860
CP032698.1|AYG81973.1|4600807_4601998_+|Kynureninase	unknown	unknown	gnl|CDD|226363
CP032698.1|AYG81984.1|4613945_4615217_+|hypothetical-protein	unknown	unknown	gnl|CDD|340863
CP032698.1|AYG81969.1|4596503_4597994_+|Multidrug-resistance-protein-Stp	unknown	unknown	gnl|CDD|129794
CP032698.1|AYG81966.1|4593067_4593616_+|Orotate-phosphoribosyltransferase	unknown	unknown	gnl|CDD|234771
CP032698.1|AYG81975.1|4603311_4603881_-|hypothetical-protein	unknown	unknown	gnl|CDD|379115
CP032698.1|AYG81967.1|4593878_4594901_+|Fructose-bisphosphate-aldolase	unknown	unknown	gnl|CDD|236406
CP032698.1|AYG81965.1|4592200_4592989_+|hypothetical-protein	unknown	unknown	gnl|CDD|185698
CP032698.1|AYG81980.1|4608669_4609509_-|hypothetical-protein	unknown	unknown	gnl|CDD|237281
CP032698.1|AYG81974.1|4602092_4602980_+|hypothetical-protein	unknown	unknown	gnl|CDD|223730
CP032698.1|AYG81982.1|4611115_4612783_+|hypothetical-protein	unknown	unknown	gnl|CDD|372705
CP032698.1|AYG81981.1|4609685_4610969_+|Adenylosuccinate-synthetase	unknown	unknown	gnl|CDD|234904

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG81972.1|4599954_4600815_+|Tryptophan-2,3-dioxygenase	gnl|CDD|188272	TIGR03036, trp_2_3_diox, tryptophan 2,3-dioxygenase. Members of this family are tryptophan 2,3-dioxygenase, as confirmed by several experimental characterizations, and by conserved operon structure for many of the other members. This enzyme represents the first of a two-step degradation to L-kynurenine, and a three-step pathway (via kynurenine) to anthranilate plus alanine. [Energy metabolism, Amino acids and amines].	6.69427e-148
CP032698.1|AYG81977.1|4604680_4606090_+|Sensor-histidine-kinase-LiaS	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	3.19031e-34
CP032698.1|AYG81978.1|4606086_4606752_+|Response-regulator-protein-VraR	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.7593e-76
CP032698.1|AYG81979.1|4607249_4608476_+|Polyketide-biosynthesis-cytochrome-P450-PksS	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.44565e-101
CP032698.1|AYG81971.1|4598775_4599852_+|hypothetical-protein	gnl|CDD|371483	pfam11350, DUF3152, Protein of unknown function (DUF3152). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	3.29175e-34
CP032698.1|AYG81970.1|4598183_4598597_+|hypothetical-protein	gnl|CDD|378646	pfam11349, DUF3151, Protein of unknown function (DUF3151). This family of proteins with unknown function appears to be restricted to Actinobacteria.	4.27641e-73
CP032698.1|AYG81983.1|4612862_4613798_-|putative-HTH-type-transcriptional-regulator	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.29036e-30
CP032698.1|AYG81968.1|4595016_4596165_+|Cystathionine-beta-lyase-PatB	gnl|CDD|224090	COG1168, MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism].	1.59739e-137
CP032698.1|AYG81976.1|4604034_4604580_+|hypothetical-protein	gnl|CDD|379860	pfam16571, FBP_C, FBP C-terminal treble-clef zinc-finger. FBP_C is a family from the C terminal end of fibronectin-binding proteins. It forms an extended four-cysteine zinc-finger with a unique structural fold. Fibronectin-binding proteins bind to elongation factor G - EF-G, which is mediated by the zinc-finger binding to the C-terminus of EF-G. FBPs release ribosomes by competing with them for EF-G.	8.56484e-89
CP032698.1|AYG81973.1|4600807_4601998_+|Kynureninase	gnl|CDD|226363	COG3844, COG3844, Kynureninase [Amino acid transport and metabolism].	2.49805e-144
CP032698.1|AYG81984.1|4613945_4615217_+|hypothetical-protein	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.76818e-41
CP032698.1|AYG81969.1|4596503_4597994_+|Multidrug-resistance-protein-Stp	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.26691e-76
CP032698.1|AYG81966.1|4593067_4593616_+|Orotate-phosphoribosyltransferase	gnl|CDD|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	9.75614e-61
CP032698.1|AYG81975.1|4603311_4603881_-|hypothetical-protein	gnl|CDD|379115	pfam13305, WHG, WHG domain. This presumed domain is around 80 amino acids in length. It is found to the C-terminus of a DNA-binding helix-turn-helix domain. This domain may be involved in binding to an as yet unknown ligand that allows a transcriptional regulation response to that molecule. The domain is named WHG after three conserved residues near the C-terminus of the domain.	2.19165e-20
CP032698.1|AYG81967.1|4593878_4594901_+|Fructose-bisphosphate-aldolase	gnl|CDD|236406	PRK09197, PRK09197, fructose-bisphosphate aldolase; Provisional.	0
CP032698.1|AYG81965.1|4592200_4592989_+|hypothetical-protein	gnl|CDD|185698	cd09021, Aldose_epim_Ec_YphB, aldose 1-epimerase, similar to Escherichia coli YphB. Proteins similar to Escherichia coli YphB are uncharacterized members of the aldose-1-epimerase superfamily. Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism, catalyzing the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family, galactose mutarotase, have shown a glutamate and a histidine residue to be critical for catalysis; the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen.	1.29445e-59
CP032698.1|AYG81980.1|4608669_4609509_-|hypothetical-protein	gnl|CDD|237281	PRK13054, PRK13054, lipid kinase; Reviewed.	0.000110551
CP032698.1|AYG81974.1|4602092_4602980_+|hypothetical-protein	gnl|CDD|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	9.55228e-13
CP032698.1|AYG81982.1|4611115_4612783_+|hypothetical-protein	gnl|CDD|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	9.30297e-35
CP032698.1|AYG81981.1|4609685_4610969_+|Adenylosuccinate-synthetase	gnl|CDD|234904	PRK01117, PRK01117, adenylosuccinate synthetase; Provisional.	0

Protein sequences

>CP032698.1|AYG81974.1|4602092_4602980_+|hypothetical-protein
MDPAERDAVEEASVFSHPPVAPDATAAYGDHPDQVIDFYAPRGARAGAPLVALLHGGAWRATYDRAHMTPFADFLARRGFAVANIEYRRGTLLPRQGDGSGAPATGQPVAGRWPDTFDDVAAAVDALPLLVRDAVPGADPRRTVLTGHSAGGHLALWAAARHVLPEGSPWRTPAPAPLRGVVALAPIADFATAVDLAVCSDAVAQLLGGPPQLGLRFPHADPSALLPTGIATAVVQGREDIVVPRAVAEAYVGAAARAGEVVGLTLLDEVGHFPLIDPAADACAVVADELAQLAY
>CP032698.1|AYG81973.1|4600807_4601998_+|Kynureninase
MSEALAGQAAALDAADELAACRALFALDDDVVYLDGNSLGALPRHVPARMQDVIAREWGQLRIRSWEESGWWTAPERIGDRIAPLVGADRGTVVVGDSTSVNVFKALVGAVRLAGDDRDEILVDASTFPTDGYVAESAARMTGRRIRALAPQEIVGALGPRTAAVLVNHVDYRSGRLNDLPAMTAAIHAAGALAVWDLCHSAGALPVGVGAHGVDFAVGCTYKYLNGGPGSPAYLYVRGDHQARFDTPLPGWNSHEDPFGMRSAYAPGDGAVRGRVGTPDILSMLALESALDVWDGVSIDAVRAKSLALTDFFLECVEAYVPAGRVSSVTPAAHAERGSQVSLSCEKAGEVMRALIERGVVGDYRRPDVLRFGFTPLYVGFADAERAAGELAALLD
>CP032698.1|AYG81972.1|4599954_4600815_+|Tryptophan-2,3-dioxygenase
MSSKMSEPVTPPEGGDAPETPNLDFAGTTPYEDYVQADVLTHLQHLRSDDPGEMVFLVTTQVMELWFTVIVHEWETASRALREDRVPVAVDALKRSVRELEALNASWTPLAQLTPAQFNSYRSALGEGSGFQSAMYRRMEFLLGDKSASMLVPHRGAPRVHAELEKALGEPSLYDEVLALLARRGHAVPASVLQRDLTRKYEPSPEVEAVWAELYAGDQNGELVRLGEALTDVGELVWRWRNDHLVATRRAMGAKAGTGGSAGVAWLEKRATKNVFPELWTARSHV
>CP032698.1|AYG81971.1|4598775_4599852_+|hypothetical-protein
MGKRGARSTTKRTGRTDQTGRASRFSQTGRASRLSQTGRAGEPGRTSRSRTARTTSNSTTSNSTTSNSTTSNSTTSNSTTSTATTSALTTPRSRTLLVVAALLGTTLLGGVALAQWPGGHGKAVEAGNTVASPMEEQSPRPVEPSPPPTPAKASGDPGRPADPGTPEEPSVPPSGPGTFTAARAAGKVVGTGGPLRRYQVQVEDGAGVSATQAAVDVQAILSDGRSWAAHGKGRFQLVADGADVVIKIATPKTTDKLCASVGDTGGELNCEVAGGVVVNLKRWAKGSPQYAGPPAEYRHLIINHEIGHLIGYHQHMGCPGPGRAAPVMMQQIKGLDGCTSNAWPYTAQGTFVTGPPAP
>CP032698.1|AYG81970.1|4598183_4598597_+|hypothetical-protein
MSLHENLLGGPAPTLLPDDPEPRDLLAQGTAPADVAAKYPTSSLAWAQLADDAFDGGRTVESYAYARTGYHRGLDSLRRAGWKGHGPVPWEHEPNRGFLRALHALARAAQAIGEDAEYERCTTFLRDSSELAAETLG
>CP032698.1|AYG81969.1|4596503_4597994_+|Multidrug-resistance-protein-Stp
MGDRWAVADNVRMGTRPARWVLLTTVLGSGMALLDSTVVNVALPHIGTDLDADMAVLQWTVNAYMLTLAGLILLGGALGDRYGRRKVFVIGVVWFAAGSLLCGVAPTAGVLIAARALQGIGGALLTPGSLAIIQSGFHPDDRARAVGVWSGLGGVGAAVGPFLGGWLVDGPGWRWVFLINVPLAALCVAVALGHVPETRDPRVHTGRFDAAGAALGALALALVTYALIEAPGQGSSGVVVGAGVAGLGLGVVFVRRERRLPDPMLPPAIFRSRIFTAVNCVTVCVYAAFGGFFFLAALQLQVVAGYSALGAGAALLPTTVLMLLLSARSGELGRRIGPRVPLTVGPLLCAAGMLLMLRVGEHAAYVSDVLPALVVLGLGMVTLVAPLTATVLASVDEGRAGLASGINNAAARAAGLLAVAALPLAAGMGPEAYRSAAEFGATFRRAMPMCAGALVLASGVAFFAVRRAGRGVVPECRMQCGVSAPALEPNPNPSTP
>CP032698.1|AYG81968.1|4595016_4596165_+|Cystathionine-beta-lyase-PatB
MTTYDFDTPVDRRGTWSIQWDGAAERFGADGLLPFTISDMDFRCPPPVLAALQERVAHGVFGYTDWQNEEFRSAVRDWYRDRHDTELDTTRLVYAPSVLSQLSQLLRMWTEPGDAVVVHTPVYDGFRRTVTGLGRELREVPLDDPAALDAALAGPRARVLLLCSPHNPTGRVWTEAELTSFASLAQRYGAAVISDEIHADFVHAGRRHLPWSRFGQGRWALITSGTKAFNFPSLTGSYGILGDAADHAEFVRRMQTGEGLGSPAVLSLTAHIAAYREGAGWLDAVRAYVAGNLALVASTLNSAFPELSWAPPQAGYLAWIDLRALGVEEGALQRELVEGERVAVMPGGVYGAPGFVRLNVGCARGKVGVGVAALVRALGRLT
>CP032698.1|AYG81967.1|4593878_4594901_+|Fructose-bisphosphate-aldolase
MPIATPEVYNEMLDRAKAGKFAYPAINVTSTQTLHAALRGFAEAESDGIIQISTGGAEFLGGQYNKDMVTGAVALAEFAHVVAAKYDITVALHTDHCPKDKLDGYVRPLLEVSAERVARGLNPLFQSHMWDGSAETLADNLAIGQELLAKAAAAKIILEVEITPTGGEEDGVSHEINDELYTTVDDALRTAEALGLGEKGRYLLAASFGNVHGVYKPGNVVLRPELLKDLQAGVAEKYGKPSPFDFVFHGGSGSSAEEIATALENGVVKMNLDTDTQYAFTRPVADHMFRNYDGVLKVDGEVGKKSTYDPRTWGKLAEAGMAKRVTEACANLRSTGTKLK
>CP032698.1|AYG81966.1|4593067_4593616_+|Orotate-phosphoribosyltransferase
MTDVRADLLQQIKDKAVVHGKVTLSSGIEADYYVDLRRVTLDGVAAPLVGQVMLDITAAFDFDAVGGLTMGADPVAGAMLHAAAARGRTLDAFVVRKAAKAHGMQRQVEGPDIKGRRVLVVEDTSTTGGSPLTAVEAVRAAGAEVVAVATIVDRATGAAEKITEGAGVPYVFAFSSEELGLA
>CP032698.1|AYG81965.1|4592200_4592989_+|hypothetical-protein
MSSDQIKLGVGAAELTVDAGNGCRISSLVIDGTEVLRQGDKYGCFPMVPWCGRVENGQFRDGGVKHQLPLNSPPHAIHGTGRDHAWHTARVSDTEAVFTYELAEPWPYTGRVTQIFELTPDALTVRMGVETYDNSFPAQVGWHPWFVREIDGSRVGLAFDAAWQEERGDDHLPTGRRIEPLPGPWDDCFGMPDGVDVTLTWPGRLELKVTSPGEWVVIYDEQAEAVCVEPQSGPPNGLNTLPRLVTPIEPLELATTWSWRRL
>CP032698.1|AYG81975.1|4603311_4603881_-|hypothetical-protein
MARVGLTTDRLVRAGAELADEVGFEQVTVSALARRFDVKVASLYSHVKNSQDLKTRLALLALEELADQAADAVAGRSGKDALAALGNVYRDYAREHPGRYAAAQLRLDPEAAAASAGRRHSQMTRAILRGYDLPEREEVHAVRLLGSVFHGYISLEMGGGFSHSAPDTQETWERTLSALDTLLRTWPTP
>CP032698.1|AYG81976.1|4604034_4604580_+|hypothetical-protein
MKPLTEQDIRASFVNCTKGEAKRLSVPRDLAERPWDDLDYLGWRDPQAPDRGYLVVELDGRPHGLALRCSSALWGRQRRSMCSMCLTTHSGGVSLMVAPKAGKAGKQGNSVGAYICADLDCSLYVRGKKDAGIGARLHETLTVEEKIERTVLNVAAFVAKVTGSPDAPVAPEAMGTPSPTA
>CP032698.1|AYG81977.1|4604680_4606090_+|Sensor-histidine-kinase-LiaS
MVDVNETTTSPRQGSGSSTVAGGGAAERTPEFRLAMDAYGGLCKDLLHDAFAYRPLPPMRTDGVITRRLPGRIREAAAWTPHAVVCFFAFLAMLFGYTGSLSGIGGGLAFMLSGLFVAVPVIVTLVRPIGAFWLSCAAIVITGLMGYHGSMTPWTPGSVFMHLTVLVVVALRTRPRVALGMWGVTFALGVMVGVVRGRSDAFGTGVQMAIFYGMVLLVISVVHIRKDAERQVSAEKSVTAVERDRRTVLEERTNIARELHDVVAHHMSVVAIQAEAAPYRVENPPPELAQAFATIRENAVSALTELRRVLGVVRAEDYEAPDAPQPTLADLDGLLANVREAGLDVEKVVTGAVRELPQGVELSAYRIIQEALSNTLRHAPGAAARVEIGYVLGGLGLRVINGRPTTEAGPSQGSGHGITGMAERVAMLGGAMTAERTAEGGYEVTVFIPVAPAEPESTVDLAKGTDERA
>CP032698.1|AYG81978.1|4606086_4606752_+|Response-regulator-protein-VraR
MTIRVLIVDDQMMVREGFSVLLGAQPDIEVVGEAVDGREAVAQVRALRPDVVLMDIRMPGMNGIEATREIVASDDSSKVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPSVTRRLINEFARVVPVARGGSSPTGQVEELTDRETEVLVLIAQGLSNQEIADRLVVAESTIKTHVSRVLVKLGLRDRTQAAVYAYETRLVTPS
>CP032698.1|AYG81979.1|4607249_4608476_+|Polyketide-biosynthesis-cytochrome-P450-PksS
MTTRNPFAPGNPDFVANPYPAYAELRATARAHHYAPTNQWLIPHHADIRTLLKDRRLGRSYRHRFTHEEFGRTSPPAAHEPFHTLNDHGMLDLEPPDHTRIRRLVSQAFTPRTVERLAPTVRRLAGRLVDDFRAAGGGDLVAEVAEPLPVAVIAEMLGIPDVDRPLLRPWSAAICGMYELNPDEDTAARAVLASREFSAYLRELIGARRKNPGGDLISALIAAYDDESEGGSRLTEQEMVSTCVLLLNAGHEATVNTTANGWWALLRNPEQLAALRAAPDALLPTAIEELMRYDTPLQLFERWVLEDIEFAGQMLRRGSEVALLFGSANRDPARFADPDTLDLTRADNPHVSFGAGIHYCLGAPLARLELHASFSELLKKAPRMRLAAEPEWGPGFVIRGLKELRVQC
>CP032698.1|AYG81980.1|4608669_4609509_-|hypothetical-protein
MSAAHQLVVLIDPVARRIDGESVRIAKDVLCAGAQAKICWPQDPQDFAGALARRGGRRTVVVGDDHTLLRTVTLLHKKRELDRGALAMVPVGPADSLELARALGVPMGAVAAARVALDGVAQPLDLLVDDCDQVVLGALRIPALSPVRVPSAPPTVWGAARSLVRTLVRAPAPVAAAMAHRLRVEADGVLLSDLDLPVAGVSVASGDGLAQVVVYGRTGERVRAAARAVTVSGPVGGFRYRADAVVGGPVRTRTWVAAAEAWQLVLPTPGAPPRTPYRA
>CP032698.1|AYG81981.1|4609685_4610969_+|Adenylosuccinate-synthetase
MPALVLLGAQWGDEGKGKATDLLGGSVDYVVRYQGGNNAGHTVVVGDQKYALHLLPSGILSPGCTPVIGNGVVVDPAVLLSELSGLNERGVDTSKLLISGNAHLITPYNVTLDKVSERFLGKRKIGTTGRGIGPTYADKINRVGIRVQDLYDESILEQKVEAALEGKNQLLAKVYNRRAIEVGKIVEEMLQYAEKLRPFVADTTLILNQALDDDKVVLFEGGQGTLLDVDHGTYPFVTSSNPTAGGACTGAGVGPTKISRVIGILKAYTTRVGAGPFPTELFDEDGEALRRIGGERGVTTGRDRRCGWFDAPIARYATRVNGLTDFFLTKLDVLTGWEEIPVCVAYEIDGKRVEELPYSQTDFHHAKPIYEKLPGWSEDITKAKTFDELPKNAKAYVKALEEMSGAPISAIGVGPGRTETIEINSFL
>CP032698.1|AYG81982.1|4611115_4612783_+|hypothetical-protein
MSMQPMESGEIPAETVRVAWAAFPKGSLAIRVRDELGPLFRDEEFADLFPARGKPAWSPGRLALVLVLQFVEGLTDRQAAEAVRARIDFKYALALELSDPGFDFSVLSEFRDRLVKAEAGRRVLDSILAAAGESGLLKTAGRARTDSTHVQSAARQLCWLEQVAETLRAALNEIAQAAPDWLLTVAEPDWFKHYATRAEDSRFPKSRAKRDELGLRIGRDGTRLLEAVFSPGAPGEPRALEQVETLRQVWVQHFQQVEGEVRRRDPKDRPPGATRLVTPYDTEARGSVKRDTMWDGYKVHLTETCEPDIPNLITNVATTVATVPDISMTDIVHAQFAQDGRLPGEHLVDAGYVDAHLLVQARREYGITLTGPVAGVVSHQTTANSGFTGDDFTIDWDHEQVTCPGGETTTRWNPDRSPEGTPVIRVRFNGGQCRPCPVREQCTTSSAGRRLTLRPREEHQALRQARAEQDTDTWKDRYKTRAGVEGTISQAVQRCGLRRSRYRGLAKTSLQHQLTGAAINLARIDAHLTDTPRARTRTSYFAALRPAELMLGGAK
>CP032698.1|AYG81983.1|4612862_4613798_-|putative-HTH-type-transcriptional-regulator
MDLEAVRTFVAVAETGRFQKAAADLAITQQAVSKRIAALERSLGVRLYTRAPRGAELTIDGQAFLPHARELLRVADRASASVRPGRRPLRVDVLASRSAQSNLMRGFHRAHPEIDLDVLMLFDIESAVAAIRSGTIDASFRAVAAPGRPLPEDIASVRVLDEPLQLLTGPAHALAGARSVTVAQLTGHRIWMPGIAPGTEWGAYYDDLVAEFGLTIEATGPNFGSDALLDTIADTPALATFMGEHTRLIWPAGHGLRRIPVTDPTPVYPHSLLWRRDNPHPALATLRAHLAAATGGHDAAGTWAPGWATSR
>CP032698.1|AYG81984.1|4613945_4615217_+|hypothetical-protein
MVGMVGNRPLGRRFGWLWASYAVSAYGSGLGFGALPLVAVLALHAGPAEVSALAAVGPAVGALIAVPLAPWVEFRRKRPVMIMMDLVRFAAMATIPVAYALGWLGFVHLLVVSAVVAAAKIAFNAASGAYLKAIVSPDDLLVANARFESTNWSSIAVGPPLGGAAIGLLGPVATVLADALSYLLSALGLTAIGGGASAVGGKGPAPVGGKGPVRAGALLDGWRHILGHPVLRSLYLNNLLVSGLIMATEPLLAVLLIRQLGFPPWQYGLAFAAPCLGGLVGSRLARRVVARFGRPWVFRTVGTLRAVWLIGLVFVGPGVVGLVTVMVVELAIIINMSLYTPVLATYRLEQTPEHLVARTLTAWSIGQQTSIAVLTALAGLLADATGPRAALAVAGLLILITPLLLPRRGRAVWTERELFRGAS

Crispr_ID: CP032698_51

• CRISPR_ID: CP032698_51
• CRISPR_location: 4638719-4638820
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_51

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGGGGG	CRISPRCasFinder

spacers of CP032698_51

>51.1|4638746|48|CP032698|CRISPRCasFinder
CCCGAACCCTTCAACGCGCTGCACGGGCGGGTGGGCGGGCGAACGGGC

CRISPR arrays and Neighbor proteins around CP032698_51

CRISPR arrays

The CRISPR arrays of CP032698_51

>merge|CP032698|51|4638719-4638820|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGGCCCGAACCCTTCAACGCGCTGCACGGGCGGGTGGGCGGGCGAACGGGCCGGGGTCTGGGGCGGAGCCCCAGGGGG

>CP032698|51|39|4638719-4638820|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGG	CCCGAACCCTTCAACGCGCTGCACGGGCGGGTGGGCGGGCGAACGGGC
CGGGGTCTGGGGCGGAGCCCCAGGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82010.1|4640684_4641647_-|L-threonine-dehydratase-catabolic-TdcB	unknown	unknown	gnl|CDD|235918
CP032698.1|AYG82003.1|4632124_4632784_+|hypothetical-protein	unknown	unknown	gnl|CDD|374737
CP032698.1|AYG82011.1|4641670_4641919_-|Sec-independent-protein-translocase-protein-TatA	unknown	unknown	gnl|CDD|234797
CP032698.1|AYG82017.1|4648367_4649084_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82013.1|4643781_4645290_+|Alkaline-phosphatase	unknown	unknown	gnl|CDD|224699
CP032698.1|AYG82016.1|4647044_4648250_-|Biflaviolin-synthase-CYP158A2	unknown	unknown	gnl|CDD|225035
CP032698.1|AYG82008.1|4637451_4638333_-|hypothetical-protein	unknown	unknown	gnl|CDD|376731
CP032698.1|AYG82007.1|4636270_4637503_+|hypothetical-protein	unknown	unknown	gnl|CDD|223021
CP032698.1|AYG82015.1|4645924_4647016_-|1,3,6,8-tetrahydroxynaphthalene-synthase	unknown	unknown	gnl|CDD|238427
CP032698.1|AYG82018.1|4649326_4649998_-|hypothetical-protein	unknown	unknown	gnl|CDD|197715
CP032698.1|AYG82005.1|4634275_4635334_+|Aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|237845
CP032698.1|AYG82002.1|4631462_4632062_+|Recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
CP032698.1|AYG82006.1|4635689_4636274_+|RNA-polymerase-sigma-E-factor	unknown	unknown	gnl|CDD|132028
CP032698.1|AYG82012.1|4642131_4643646_+|Putative-transcriptional-regulator-YvhJ	unknown	unknown	gnl|CDD|367673
CP032698.1|AYG81999.1|4629210_4629861_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82001.1|4631039_4631348_+|Nucleoid-associated-protein	unknown	unknown	gnl|CDD|234669
CP032698.1|AYG82004.1|4632998_4634279_+|Aspartokinase	unknown	unknown	gnl|CDD|235843
CP032698.1|AYG82014.1|4645390_4645909_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82009.1|4638827_4640591_-|Dipeptidyl-aminopeptidase-BIII	unknown	unknown	gnl|CDD|224423
CP032698.1|AYG82000.1|4629885_4630626_-|hypothetical-protein	unknown	unknown	gnl|CDD|375613

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82010.1|4640684_4641647_-|L-threonine-dehydratase-catabolic-TdcB	gnl|CDD|235918	PRK07048, PRK07048, threo-3-hydroxy-L-aspartate ammonia-lyase.	0
CP032698.1|AYG82003.1|4632124_4632784_+|hypothetical-protein	gnl|CDD|374737	pfam16702, DUF5063, Domain of unknown function (DUF5063).	2.95825e-51
CP032698.1|AYG82011.1|4641670_4641919_-|Sec-independent-protein-translocase-protein-TatA	gnl|CDD|234797	PRK00575, tatA, Sec-independent protein translocase subunit TatA.	6.64093e-23
CP032698.1|AYG82013.1|4643781_4645290_+|Alkaline-phosphatase	gnl|CDD|224699	COG1785, PhoA, Alkaline phosphatase [Inorganic ion transport and metabolism].	3.66266e-100
CP032698.1|AYG82016.1|4647044_4648250_-|Biflaviolin-synthase-CYP158A2	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.04424e-86
CP032698.1|AYG82008.1|4637451_4638333_-|hypothetical-protein	gnl|CDD|376731	pfam02104, SURF1, SURF1 family.	2.80464e-29
CP032698.1|AYG82007.1|4636270_4637503_+|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	0.00284449
CP032698.1|AYG82015.1|4645924_4647016_-|1,3,6,8-tetrahydroxynaphthalene-synthase	gnl|CDD|238427	cd00831, CHS_like, Chalcone and stilbene synthases; plant-specific polyketide synthases (PKS) and related enzymes, also called type III PKSs. PKS generate an array of different products, dependent on the nature of the starter molecule. They share a common chemical strategy, after the starter molecule is loaded onto the active site cysteine, a carboxylative condensation reation extends the polyketide chain. Plant-specific PKS are dimeric iterative PKSs, using coenzyme A esters to deliver substrate to the active site, but they differ in the choice of starter molecule and the number of condensation reactions.	1.10939e-104
CP032698.1|AYG82018.1|4649326_4649998_-|hypothetical-protein	gnl|CDD|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	4.43392e-05
CP032698.1|AYG82005.1|4634275_4635334_+|Aspartate-semialdehyde-dehydrogenase	gnl|CDD|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	8.96899e-130
CP032698.1|AYG82002.1|4631462_4632062_+|Recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	5.08792e-123
CP032698.1|AYG82006.1|4635689_4636274_+|RNA-polymerase-sigma-E-factor	gnl|CDD|132028	TIGR02983, putative_RNA_polymerase_ECF-subfamily_sigma_factor, RNA polymerase sigma-70 factor, sigma-E family. This group of similar sigma-70 factors includes the sigE factor from Streptomyces coelicolor. The family appears to include a paralagous expansion in the Streptomycetes lineage, while related Actinomycetales have at most two representatives.	3.65188e-51
CP032698.1|AYG82012.1|4642131_4643646_+|Putative-transcriptional-regulator-YvhJ	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	1.65988e-46
CP032698.1|AYG82001.1|4631039_4631348_+|Nucleoid-associated-protein	gnl|CDD|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	8.82306e-35
CP032698.1|AYG82004.1|4632998_4634279_+|Aspartokinase	gnl|CDD|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
CP032698.1|AYG82009.1|4638827_4640591_-|Dipeptidyl-aminopeptidase-BIII	gnl|CDD|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	7.0068e-48
CP032698.1|AYG82000.1|4629885_4630626_-|hypothetical-protein	gnl|CDD|375613	pfam18183, SLATT_2, SMODS and SLOG-associating 2TM effector domain 2. The SLATT domain contains two transmembrane helices. SLATT domains are generally predicted to function as pore-forming effectors in a class of conflict systems which are reliant on the production of second messenger nucleotide or nucleotide derivatives. SLATT domains are predicted to initiate cell suicide responses upon their activation. This SLATT family is the only prokaryotic SLATT family to exist as a standalone domain, with no as-yet discernable genome associations.	2.43069e-119

Protein sequences

>CP032698.1|AYG82008.1|4637451_4638333_-|hypothetical-protein
MYRFLLTPRWWAIHAFVLLAIPVCVFMGSWQLGRFEDRVQSHDAATKAPDPASLKAEPLASLLPVDQRTSGRPAVAHGRYAEQFLVPGREVDGASGSYVLTLLRTDGAKALPVVRGWIPRGAQAPAAPSGEVEVTGVLQASETVGSDGVHAQGGLPRGQVGVISAAALVNLVPYPVYDAWVTLPTADAGMTAVPASAPQNSGLDLKAFQNLGYTGEWFVFAGFVVFMWFRLVRREAEALEDAELGLAPEGGSETPPASQPTPEGAAAPEGSETPGGPYGVDDADAPASSTPVL
>CP032698.1|AYG82007.1|4636270_4637503_+|hypothetical-protein
MKGSDRNDERFPGEHGQRGQRGEHGKSGSDQRPRNDLNDLTGYGFVDKTPETNNTGTPPFGFPPAPGSTDAADERALRRLLHGTVEDLKPSEGALEHLRAAVPLRRARKRQAVVGSIAAALLVATAVPAFLHVANTAGSADDLPAVAGHGERTHGTPDPASDTVEATDAGGRPSSAGSAPGTPGGKGPRATPTKGATGGTAGGATGAGSGPVKANSPVCEAAELSVKSAKVGKPDSTGKVYGAFRIVNASDKQCAIGGVGKFNVRAQGAADPAKITVVEHAVGDPAPGLPDPSQDATALVLQPAAAYEVRFAWVPSDTCPKATPTPDPTPSNGGSSSSGIVAPTTGGSTGTSQLAPNGGTPTATADGTVAVTHVAEPGAPSAEAKIPNACAGTIYKTGVLDAGASASSTP
>CP032698.1|AYG82006.1|4635689_4636274_+|RNA-polymerase-sigma-E-factor
MPVIAPMPAPRTVRPPAQATSRESADEVMAAGTTVDHLTETYRAHYRSLLGLAALLLDDIASCEDVVQEAFIRVHSARSRVREPEKTLAYLRQTVVNLSRSALRRRILGLKLLSKPMPDMASAEEGAYDQLERDALIKAMRGLQRRQREVLVLRYFADMTEAQVAETLGISLGSVKAYGSRGIAALRVAMEATA
>CP032698.1|AYG82005.1|4634275_4635334_+|Aspartate-semialdehyde-dehydrogenase
MTPRPALTVVGATGGAGAVMLQILTQHADVWGEVRLVASARSAGRKLLVRGAECEVLALGEEALEGADVVVFLVPAEVAARWAPVAAAKGAVVVDSSAAFRMDPDVPLVVPELNPHAVRMRPRGIVASPHATTLAMSVAVGALHAEFCLSELVVSTYQAASGEGQPGVEALRRQVSLVAGTQLGTNPGDVRRAVGDELGPFPAPLALNVVPWTGELADDGWSSQELGIRDELRKVLGLPRLPVSATCVRVPVVTTHSASVHARFENEVEVARAHEILATAPGVVLFDNPAVGEFPTPADVVGTDPTWVGRVRRSPDDPRVLELFVCGDNLRKGTALNAAHIAELAAREFNGR
>CP032698.1|AYG82004.1|4632998_4634279_+|Aspartokinase
MGLVVQKYGGSSVADAEGIKRVAKRIVEAKKNGHQVVVVVSAMGDTTDELIELAEQVSPMPAGREFDMLLTAGERISMALLAMAIKSLGHQAQSFTGSQAGVITDSVHNKARIIDVTPGRIRTSIDEGNIAIVAGFQGVSQEGKNITTLGRGGSDTTAVALAAALDAEVCEIYTDVDGVFTADPRVVKKAKKIEWISFEDMLELAASGSKVLLHRCVEYARRYNIPIHVRSSFSGLQGTWVSNEPRSQSEGQQVEHAIISGVAHDVSEAKVTVVGVPDKPGEAAAIFRTIADAEINIDMVVQNVSAASTGLTDISFTLPKAEGRKAIDALERSKPTIGFESLRYDDQIAKISLVGAGMKTNPGVTAGFFEALSDAGVNIELISTSEIRISVVTRADDVNNAVRAVHSAFGLDSDSDEAVVYGGTGR
>CP032698.1|AYG82003.1|4632124_4632784_+|hypothetical-protein
MSDATLHATTQDPDSFAVQIADQVESFIVAVTEVAKGDEPDSAVPFLLLEFSQLLLAGGRLGAHEDIVPDEPYEPDLGPEADVDELRERFARLLEPIDVYSEVFDPYEPRKAPVPCRISDDIADVVTDLRHGLAHYRAGRISEALWWWQFSYFSNWGSTASAALRALQSLVAHVRLDQPLPELDGLDTDEDLAEGALEEEAGRVMAEELAGPLGLHDLK
>CP032698.1|AYG82002.1|4631462_4632062_+|Recombination-protein-RecR
MYEGVVQDLIDELGRLPGVGPKSAQRIAFHILQTEPTDVRRLAHALLEVKDKVRFCAVCGNVAQEERCAVCRDPRRDQTVICVVEEPKDVVAIERTREFRGRYHVLGGAISPIEGVGPDDLRIRELLARLADGTVTELILATDPNLEGEATATYLARMIKPMGLRVTRLASGLPVGGDLEYADEVTLGRAFEGRRLLDV
>CP032698.1|AYG82001.1|4631039_4631348_+|Nucleoid-associated-protein
MQQLLQQAQKMQQDLAVAQEELAATEVEGQAGGGLVKATVTGSGELRALAIDPKAVDPEDTETLADLIVAAVQAANDNAQQLQQQKLGPLAQGLGGMPGLPF
>CP032698.1|AYG82000.1|4629885_4630626_-|hypothetical-protein
MSQPDMQPEGPPGQARRDEGAQTGDLTGRPFPRGDWGEPAERLDELYRWVETGALRTAEWYLADRLWKRRGARVLRCGTASGAIAGAVLPLLDLTEALKGAAGWGYLCLLLAAACMACDRYFGLTSGWIRDVATAQAVQRRLQGLQFDWASESVREVLGPTDGTAGEAAERCLSVLRRFTEDVMDLVRSETADWMVEFRSGPAPLVMQTLSTAAPRTDAAPGPGRFPLPPATRPNMPRQRPPEGPR
>CP032698.1|AYG81999.1|4629210_4629861_+|hypothetical-protein
MACDLWLVPLVDVLCHSPDNPFAEEIASYDKALGDAGLPPVPVFAYMPGLSGDVAPVAGFDYDALHFLRRAYLLQLCGLAVTPVDELGGDYEQLLEMFESTAQQSHLVWHYDHAGAYVPVDFAMPLSNEELLAGGGPLGSAQGLLRELQFVGPAIGIDPANPPTAPAPPARPTSLEEPAGPIPYDESPFARERHVWLGLHAAATRSLAQGSMIIFS
>CP032698.1|AYG82009.1|4638827_4640591_-|Dipeptidyl-aminopeptidase-BIII
MPDWEKRFRAPRVGLPDWAEDAPDRSLFVSNATGTYELYAWDRTTGEQRRATDRPNGTTDGVLTPDGAWIWWFDDTDGDEFGVWRRQPFTGGADEHAVPGLAPSYPAGLALGRDGTAVVGRSTDEDGSTIHVVRPGADPVEIYRHRESAGVGDLSHDGTLIALEHTEHGDAMHSALRVVRPDGSAVAELDDTKGGTEELGLEVLGFAPLAGDTRLLVAHQRRGRWEPMIWDVASGEESDLALDLPGDVSAEWYPDGSGLLVVHSFEARSGLFRFDLATRSLIEIETPAGSVSSATARPDGTVEYLWSSAASPSEVRSTTGEVVLDPPGFKAPGSVPVTDAWVEGPGGRIHALVQRPAGEGPFPTLFEIHGGPTWHDSDAFASGPAAWIDHGYAVVRVNYRGSTGYGRAWTDALKHRVGLIELEDIAAVRDWAVSSGLADPERLVLAGGSWGGYLTLLGLGTQPEAWALGLAAVPVADYVTAYHDEMEALKAMDRTLLGGTPEEVPERFRASSPLTYVDAVAAPVYISAGVNDPRCPIRQVENYVERLVARGAVHEVYRYDAGHGSLVVEERIKQVRLELDFASRHLS
>CP032698.1|AYG82010.1|4640684_4641647_-|L-threonine-dehydratase-catabolic-TdcB
MEKLPTYDDVVRAHERITGHAHRTPVLTSRLTDAELGLSLFLKCENLQRMGAFKFRGAFNALSRFDAEQRRAGVVAYSSGNHAQALALSGALLGIPVTIVMPHDAPASKLAATKGYGANVVSYDRWTESREEIGRALADRHGLTLIPPFDHPHVMAGQGTAAKELFEETGPLDALFVPLGGGGLLSGSLLAANALAPSCAVYGVEPEAGDDGLRSLRAGEIVRIDTPATIADGAQTQQLGAHTFPVIRDHVSDIITVSDAQLVDSMRLLGSRMKIVAEPTGCLGLAGARDLAERYRGGRVGVILSGGNVDMARFAELLSK
>CP032698.1|AYG82011.1|4641670_4641919_-|Sec-independent-protein-translocase-protein-TatA
MFLRNGLEPWHLLIVGVVLILLFGSKKLPDTARALGKSLRILKSETKAMREESEGPVPAAAPAPQVAPAPVAPADAPPRTTA
>CP032698.1|AYG82012.1|4642131_4643646_+|Putative-transcriptional-regulator-YvhJ
MAGSHKAGAASRGESGGSAMPRGRDKRSRARIAGITGLSVVVLAVAGGGWIYLKLNGDIKTFDDGGVSADRPAASTEGSNVLVIGSDTRSGDNAQYGHGKGDIGRSDTAFLLHVYGDQKHAVAVSIPRDSLVDIPPCKLPDGNWTKEKHRVMFNSAFEVGETVQGNPACTQNTVEKLTGLRVDHTVIVDFAGFAKMTEAVGGVGVCVPNNVYQGDLNPKLGHKGSLVFAKGEQNVSGQKALDYVRIRHGIGDGSDIGRIQRQQAFVGSLIKKVKGNGLDPTSLLPLASAATKSMTVDSGLGSANKLISFAMSMKNIDLHNTKFVTLPWRYEGERVAVVKPEADALFAALRADRTIDGKDAAGKSAASASPTPTAAAAPPASGKGVSVAVYNGTTTKGLASKVATSLRSAGFTVTGATTAATQDYTQTVIEYGASSEAKAKTLATHFPGAVLRQAKAPGLNVIVGTEYKADGADAAPSAAASVPPAVAEKARSADDSICSNLSYG
>CP032698.1|AYG82013.1|4643781_4645290_+|Alkaline-phosphatase
MKVLAVVAAASAVAAGSAVTANSAPAHGDHGGNDREIRNVIYLLGDGMGRTHVTAGRERFYGAQGKLNMERLPYTGAVATYAVEKGTDQPSLVTDSASSATAWSSGVKTYNAAIGVDSYEKRRVTLMEQAKAAGFATGNVSTAEITDATPAAQFSHALLRGCQGPTYSDAACLPKNADGSYEKAPADKTLITPIAEQIARNGTADVVLGGGLARFEPDDQKALQKQGYQVLGSFGDPKLPAQNADSQKVATKADLDKARGRKVVGLFNRGNLTVEQAKAGLPANAPQKQEPTLAEMAKKSIDLLDGRSRKGFFLQIEGAQIDKRSHANDAAQTLGEVKAFDDAVKAATDFAKRDGHTLVIVTADHECAGFNIVEKGTYTNAEAVAPPANTDAGNPANNSGTSRPSSGAKDPARSTGIANGTGAGDVKNFAPATFRTPDDPKNVKDGSPEASLWLTYLSGNHTGADVPIFAYGPGADRFAASQINTDLYKKMYGSLFGRSPRG
>CP032698.1|AYG82014.1|4645390_4645909_+|hypothetical-protein
MRRTAVPAVPAVLAALGLALVTGCGGGSGERADDTPDPVPSVSFAAPRHAAEPAAYQKLSRGEVRLEQGPFTDRVKVTGQALGAGPAVTGHLAVTSDVSELIALELRAAYYDANGKLLGTGSFQYAEEGHEEHPGGHAPAAEGAGIDFAVRPSALTGTPTSAVLSIPVLVNE
>CP032698.1|AYG82015.1|4645924_4647016_-|1,3,6,8-tetrahydroxynaphthalene-synthase
MATLCRPAVAVPEHVITQEQTLALAREMHAGHPQRDLVLRLIENTGVLTRHLVQPLDVTLDHPGFELRNQVYEAEAKRRVPDVVREALAHADVEPGDIDLIVYVSCTGFMMPSLTAWLINTMGFRSDTRQLPIAQLGCAAGGAAINRAHDFITAYPGSNVLIVSCEFCSLLYQPTDIGVGSLLSNGLFGDAVSAAVVRGEGGTGMRIERNGSHLVPDTENWISYAVRETGFHFQLDKRVPGTMEMLAPALKTLVAQHSWEVGGLDFYIVHAGGPRILDDLCHFLELGPEMFRFSRATLTERGNIASSVVFDALARLFDEGGMEDGARGLIAGFGPGITAEMGVGRWNAGPGIDRELSALTAQA
>CP032698.1|AYG82016.1|4647044_4648250_-|Biflaviolin-synthase-CYP158A2
METTDTVWSCPFDYADALEFDPQLRRMLAEEPVARIRMAYGEGEAWLVTRYEDVRTVTTDRRFSRSAVIGRDFPRMTPEPIVQAESINLMDPPASSRLRSLVAKSFAPKHVARMRERTQRVVDELLDTMAAHGSPADFVEHIAAPLPLVTICEVLAIPDGERDWLRAHALTMMNIGAAGREAAVRAKAELRAYFTDLTAARRRSPGDDLISTLATARDGDELLDDQELAVMAMVLLITGQDTTTYELGNIAYTLLTRPDILDGLRARPDRFPAVLDELLRFIPFRKGVGIPRVATEDVELSGVLIRAGDIVHVSYLTANRDDRKFDRPHEIDPERGSVPHMTFGWGAHHCLGAPLAQMELEVAFTSLLTRFPGIRAAGEPSDVPWNTHSIWRHPLSLPVAW
>CP032698.1|AYG82017.1|4648367_4649084_+|hypothetical-protein
MGGAGMVRAGGLGVPGAAGPRGWGGLALRLGRVVWAWGRSRLLGPAGRGWWFGRGGRGWWFGPGGRAGWLAQRAWVGGLALGAGLVALPCGLGLAVWLWGPSWVVWPCGPCLRLAQFPAPPKPPVMCGSGSLLAQFLAPLKTRVRLRTVPASRAVPRAPGNPCSSADRARFSRSSPRPWKPAFVCGPCPLLAQFPAPLETRVRLRVAGGWSRSSPRPELLGAGPRRPPQPVMGVPPGP
>CP032698.1|AYG82018.1|4649326_4649998_-|hypothetical-protein
MNDEPMVTLHGERALIDRAGHLFAGVRHEFLVAAADPLTWSAGVRTAFAAGLRPATEPGGLALRKLYTPEALPDARAERRLTRMAAGGAHIRICSAPLGQETIVLDRRVAILAGAPGAGPRTYTVIRTPDVVAGLRSLVQAAWEASPDLDAHLLRRAPVLGADARRILRTLGAGHTDEAASRHLGMSLRTYRRRVAELMEMLGATSRFQAGLRARELEGGHVG

Crispr_ID: CP032698_52

• CRISPR_ID: CP032698_52
• CRISPR_location: 4813625-4813734
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_52

Consensus_repeat	Method
CCCCACCCCGGACGCCACGCTCCCGG	CRISPRCasFinder

spacers of CP032698_52

>52.1|4813651|58|CP032698|CRISPRCasFinder
GCACCCCGGACACCACGCACACGCGAACCCCGCACCCCGCGCCCGTGGGCACCGCCGC

CRISPR arrays and Neighbor proteins around CP032698_52

CRISPR arrays

The CRISPR arrays of CP032698_52

>merge|CP032698|52|4813625-4813734|CRISPRCasFinder
CCCCACCCCGGACGCCACGCTCCCGGGCACCCCGGACACCACGCACACGCGAACCCCGCACCCCGCGCCCGTGGGCACCGCCGCCCCCACCCCGGACGCCACGCGTCCCG

>CP032698|52|40|4813625-4813734|CRISPRCasFinder
CCCCACCCCGGACGCCACGCTCCCGG	GCACCCCGGACACCACGCACACGCGAACCCCGCACCCCGCGCCCGTGGGCACCGCCGC
CCCCACCCCGGACGCCACGCGTCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82145.1|4804975_4806127_+|Acyl-CoA-dehydrogenase-fadE12	unknown	unknown	gnl|CDD|173838
CP032698.1|AYG82158.1|4816632_4817874_-|D-inositol-3-phosphate-glycosyltransferase	unknown	unknown	gnl|CDD|340836
CP032698.1|AYG82164.1|4824896_4825136_+|hypothetical-protein	unknown	unknown	gnl|CDD|367652
CP032698.1|AYG82150.1|4809785_4809980_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82163.1|4823076_4824240_-|Putative-teichuronic-acid-biosynthesis-glycosyltransferase-TuaC	unknown	unknown	gnl|CDD|340837
CP032698.1|AYG82147.1|4807806_4808568_+|Enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|236109
CP032698.1|AYG82160.1|4818645_4820262_-|putative-lipid-II-flippase-MurJ	unknown	unknown	gnl|CDD|240528
CP032698.1|AYG82154.1|4811910_4813269_+|hypothetical-protein	unknown	unknown	gnl|CDD|367652
CP032698.1|AYG82157.1|4815964_4816636_-|hypothetical-protein	unknown	unknown	gnl|CDD|226453
CP032698.1|AYG82159.1|4817870_4818572_-|Poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase	unknown	unknown	gnl|CDD|213023
CP032698.1|AYG82151.1|4810162_4810756_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82161.1|4820258_4821593_-|hypothetical-protein	unknown	unknown	gnl|CDD|377422
CP032698.1|AYG82165.1|4825291_4826185_+|Levansucrase	unknown	unknown	gnl|CDD|223021
CP032698.1|AYG82162.1|4821595_4823080_-|UDP-glucose:undecaprenyl-phosphate-glucose-1-phosphate-transferase	unknown	unknown	gnl|CDD|274398
CP032698.1|AYG82148.1|4808555_4809143_+|HTH-type-transcriptional-repressor-AcnR	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG82156.1|4814834_4815965_-|hypothetical-protein	unknown	unknown	gnl|CDD|379214
CP032698.1|AYG82152.1|4810892_4811303_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82149.1|4809217_4809625_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82153.1|4811579_4811813_+|hypothetical-protein	unknown	unknown	gnl|CDD|367652
CP032698.1|AYG82146.1|4806146_4807784_+|Long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|341230

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82145.1|4804975_4806127_+|Acyl-CoA-dehydrogenase-fadE12	gnl|CDD|173838	cd00567, ACAD, Acyl-CoA dehydrogenase. Both mitochondrial acyl-CoA dehydrogenases (ACAD) and peroxisomal acyl-CoA oxidases (AXO) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. In contrast, AXO catalyzes a different oxidative half-reaction, in which the reduced FAD is reoxidized by molecular oxygen. The ACAD family includes the eukaryotic beta-oxidation enzymes, short (SCAD), medium (MCAD), long (LCAD) and very-long (VLCAD) chain acyl-CoA dehydrogenases. These enzymes all share high sequence similarity, but differ in their substrate specificities. The ACAD family also includes amino acid catabolism enzymes such as Isovaleryl-CoA dehydrogenase (IVD), short/branched chain acyl-CoA dehydrogenases(SBCAD), Isobutyryl-CoA dehydrogenase (IBDH), glutaryl-CoA deydrogenase (GCD) and Crotonobetainyl-CoA dehydrogenase. The mitochondrial ACAD's are generally homotetramers, except for VLCAD, which is a homodimer. Related enzymes include the SOS adaptive reponse proten aidB, Naphthocyclinone hydroxylase (NcnH), and and Dibenzothiophene (DBT) desulfurization enzyme C (DszC).	7.94949e-86
CP032698.1|AYG82158.1|4816632_4817874_-|D-inositol-3-phosphate-glycosyltransferase	gnl|CDD|340836	cd03807, GT4_WbnK-like, Shigella dysenteriae WbnK and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. WbnK in Shigella dysenteriae has been shown to be involved in the type 7 O-antigen biosynthesis.	4.38418e-73
CP032698.1|AYG82163.1|4823076_4824240_-|Putative-teichuronic-acid-biosynthesis-glycosyltransferase-TuaC	gnl|CDD|340837	cd03808, GT4_CapM-like, capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.	1.9211e-74
CP032698.1|AYG82147.1|4807806_4808568_+|Enoyl-CoA-hydratase	gnl|CDD|236109	PRK07827, PRK07827, enoyl-CoA hydratase family protein.	2.85598e-117
CP032698.1|AYG82154.1|4811910_4813269_+|hypothetical-protein	gnl|CDD|367652	pfam03777, DUF320, Small secreted domain (DUF320). Small domain found in a family of secreted streptomyces proteins. It occurs singly or as a pair. Many of the domains have two cysteines that may form a disulphide bridge.	5.16847e-17
CP032698.1|AYG82157.1|4815964_4816636_-|hypothetical-protein	gnl|CDD|226453	COG3944, COG3944, Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane].	0.000112077
CP032698.1|AYG82159.1|4817870_4818572_-|Poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase	gnl|CDD|213023	cd10918, CE4_NodB_like_5s_6s, Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, hemin storage system HmsF protein in gram-negative species, intercellular adhesion proteins IcaB, and many uncharacterized prokaryotic polysaccharide deacetylases. It also includes a putative polysaccharide deacetylase YxkH encoded by the Bacillus subtilis yxkH gene, which is one of six polysaccharide deacetylase gene homologs present in the Bacillus subtilis genome. Sequence comparison shows all family members contain a conserved domain similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, which consists of a deformed (beta/alpha)8 barrel fold with 6 or 7 strands. However, in this family, most proteins have 5 strands and some have 6 strands. Moreover, long insertions are found in many family members, whose function remains unknown.	1.31524e-49
CP032698.1|AYG82164.1|4824896_4825136_+|hypothetical-protein	gnl|CDD|367652	pfam03777, DUF320, Small secreted domain (DUF320). Small domain found in a family of secreted streptomyces proteins. It occurs singly or as a pair. Many of the domains have two cysteines that may form a disulphide bridge.	2.4841e-21
CP032698.1|AYG82161.1|4820258_4821593_-|hypothetical-protein	gnl|CDD|377422	pfam04932, Wzy_C, O-Antigen ligase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.	2.27891e-11
CP032698.1|AYG82165.1|4825291_4826185_+|Levansucrase	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	4.99986e-11
CP032698.1|AYG82148.1|4808555_4809143_+|HTH-type-transcriptional-repressor-AcnR	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.42108e-11
CP032698.1|AYG82156.1|4814834_4815965_-|hypothetical-protein	gnl|CDD|379214	pfam13480, Acetyltransf_6, Acetyltransferase (GNAT) domain. This family contains proteins with N-acetyltransferase functions.	3.43187e-15
CP032698.1|AYG82160.1|4818645_4820262_-|putative-lipid-II-flippase-MurJ	gnl|CDD|240528	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	1.62195e-68
CP032698.1|AYG82162.1|4821595_4823080_-|UDP-glucose:undecaprenyl-phosphate-glucose-1-phosphate-transferase	gnl|CDD|274398	TIGR03025, EPS_sugtrans, exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase. Members of this family are generally found near other genes involved in the biosynthesis of a variety of exopolysaccharides. These proteins consist of two fused domains, an N-terminal hydrophobic domain of generally low conservation and a highly conserved C-terminal sugar transferase domain (pfam02397). Characterized and partially characterized members of this subfamily include Salmonella WbaP (originally RfbP), E. coli WcaJ, Methylobacillus EpsB, Xanthomonas GumD, Vibrio CpsA, Erwinia AmsG, Group B Streptococcus CpsE (originally CpsD), and Streptococcus suis Cps2E. Each of these is believed to act in transferring the sugar from, for instance, UDP-glucose or UDP-galactose, to a lipid carrier such as undecaprenyl phosphate as the first (priming) step in the synthesis of an oligosaccharide "block". This function is encoded in the C-terminal domain. The liposaccharide is believed to be subsequently transferred through a "flippase" function from the cytoplasmic to the periplasmic face of the inner membrane by the N-terminal domain. Certain closely related transferase enzymes, such as Sinorhizobium ExoY and Lactococcus EpsD, lack the N-terminal domain and are not found by this model.	1.46845e-109
CP032698.1|AYG82153.1|4811579_4811813_+|hypothetical-protein	gnl|CDD|367652	pfam03777, DUF320, Small secreted domain (DUF320). Small domain found in a family of secreted streptomyces proteins. It occurs singly or as a pair. Many of the domains have two cysteines that may form a disulphide bridge.	4.81055e-24
CP032698.1|AYG82146.1|4806146_4807784_+|Long-chain-fatty-acid--CoA-ligase	gnl|CDD|341230	cd05904, 4CL, 4-Coumarate-CoA Ligase (4CL). 4-Coumarate:coenzyme A ligase is a key enzyme in the phenylpropanoid metabolic pathway for monolignol and flavonoid biosynthesis. It catalyzes the synthesis of hydroxycinnamate-CoA thioesters in a two-step reaction, involving the formation of hydroxycinnamate-AMP anhydride and the nucleophilic substitution of AMP by CoA. The phenylpropanoid pathway is one of the most important secondary metabolism pathways in plants and hydroxycinnamate-CoA thioesters are the precursors of lignin and other important phenylpropanoids.	0

Protein sequences

>CP032698.1|AYG82154.1|4811910_4813269_+|hypothetical-protein
MRQVISKTLFTAVAATSVLSMSANCAQAAGADAESVGSPGVLSGNTISAPVEVPVQACGNSVNPVGALNPSFGNNCATVSSSGERADDDAAYMADHAGEDAGRPGAPSHDYGDFYAREYAAAHAPEHHAGGSQAHSVTSGSPGVVSGNSAAAPVDVPVQACGNSVSVVGLLNPTFGNHCATNPATHEPHRSAPPRHVPPTRHAAPPVHHAAPPVHQVPPAHHAAPPVHQAPPAHHAAPPVHQAPPAHHAAPPAHHVPPVHQAPPMHQAPPTHEVPPAHQAPSVHHAPPVHQAPPMHEAPPTHATPRVHDAPPAHHAHHAHHVPPHHCPPGHEAHHAPPERHLPPVHEAPPVHHAPPVHQAPPVHHAPPVHAAPPVHQAPPVHHAPPVHDTPRHARHAVPARPDARVVAPVASAHLADTGADPALLAAAAAGAAGLVLGGSVLYRRGRAMAKG
>CP032698.1|AYG82153.1|4811579_4811813_+|hypothetical-protein
MKYMKAATVLTGFVLAAGGAAPAFADAGAQGAAVGSPGVLSGNVVQIPIHIPVNICGNTVNVIGLLNPAFGNTCINK
>CP032698.1|AYG82152.1|4810892_4811303_+|hypothetical-protein
MLKKVMAASAAAVSIVGASAMLAPQAMAIGNDTGTTSLSGNGAKQAFGNSKTEGDMSPQLSLVQGSLNKPCIGLPLKADIQNIVALVNVGVQDIPILSSPQTQQCTENSTQAKRDEALSHILDDIPVLSGNGASGS
>CP032698.1|AYG82151.1|4810162_4810756_-|hypothetical-protein
MPDTTPKTLPSDLHIISIQKAAETCSALFSYGRKSEEKKPIRRLDCWAGGSVWGIHQKGTSVIKKAMAAAAVGVSVIGASAAMAPQAMAIGNDSGTTTVSGNNALQSYGNSATYGNMSPQIALIQGSFNKPCIALPAKANIQNILALVNVGIQDIPVLSSPQTQQCTENSTQAKGDEALSHILSNIPILSGNGASHS
>CP032698.1|AYG82150.1|4809785_4809980_+|hypothetical-protein
MTETQGAWRRQTFIPITRRRFESEAEAEPVYADLVRSWAAERRTVPGRPDWEWNALVNGFRWPD
>CP032698.1|AYG82149.1|4809217_4809625_-|hypothetical-protein
MQKLWSAAAVAAAVSGVAMMAAPQAMAIGNDSGTTSLSGNGAEQAFGNSKTDGDMSPQMTLVQGSLNKLCVGLPAKADIQNIVALVNVGVQDIPVLSSPQTQQCTENSTQAKRDEALSHILDDIPVLSGNGADGS
>CP032698.1|AYG82148.1|4808555_4809143_+|HTH-type-transcriptional-repressor-AcnR
MGVVTPPKTPKQDRSRATRQRLLEAAVACLAEHGWAGSTVSVVAERAGVSRGAAQHHFPTREDLFTAAVEYVAEQRSFALRALDRSDRRHVVSALVGLYTGPLFRAALHLWVAAANEPQLHARVIELEAKVGRESHRIAVELLGADESVPGVRETVQGLLDMARGLGLANLLTDDAARRERVVAQWAVLLDEALR
>CP032698.1|AYG82147.1|4807806_4808568_+|Enoyl-CoA-hydratase
MKAPTEGPDVSVVKTTHERGIATLTLDAPANRNALSAPLVSELGAALARCAGDRDVRAVVLTHTGTTFCAGADLKAPADPGAFVALMRAVVALPKPVVARVTGHVRAGGLGLLAACDIAVAGPASSYAFTEVRLGLAPAVISMPVLPRMDPRAASRYYLTGERFDAAEAARTGLVTLAADDVDSALQPVLDGLRRSSPEGLAASKALLTATVSETFDRWSKELTARSASLFASAEAREGVTAFLERRDPAWVL
>CP032698.1|AYG82146.1|4806146_4807784_+|Long-chain-fatty-acid--CoA-ligase
MNSPAVPAPQGPRVHRSEYADVPVVDEPIHEAVLARSAALHPDAVALIDADDPDASGTTTYAQLDVRHRALAAALIASGLRKGDVLALHSPNSVLYPVVFYGASRAGAAVTTVHPMCTAEEFAKQLADSRARWIVTVSPLLDTARRAADLAGTIQEILVCDRAEGHRSIVHDLLSDAPETPVPAVPIDPAQDIAVLPYSSGTTGAPKGVMLTHRNIATNLAQLHPLVPMVPGDRILAVLPFFHIYGMTALLNAPLQAGATVVVLARFDLDPFLRAIERHRITGLYVAPPIVLALAKHPAVDRYDLSSIEYIVSAAAPLDPRLAQACSDRLGLPPIRQGYGMTELSPATHIVPLATEDPPPGAVGRLLPSTEMRILRLDDPGRDAEPGEEGEIAIRGPQVMKGYLGRPEATAALIDPAGWVHTGDVGRVDGDGWLYVVDRVKELIKYKGFQVAPADLEALLLTHPAIADAAVIGVPDTDGNEVPKAFVVRGPGAADLDADEVMAHVAERVAPYKKIRRVEFIDAVPRAVSGKILRRELRLREKDRT
>CP032698.1|AYG82145.1|4804975_4806127_+|Acyl-CoA-dehydrogenase-fadE12
MTGVIESQENKDLRAAVAALGARHGRGFDRAALWSEAAKLGYLGVNLPEEYGGGGGGMAELSIVLEELGAAGCPLLMMVVSPAICGTVIARFGTEEQRRTWLPGLADGSLTMAFGITEPDAGSNSHRITTTARRDGDDWILTGRKVFISGVDIADATLIVGRTRSAPDDATGRPAGLKPCLFIVPRDTPGFERTGIDMELQAAEKQFELVLDDVRLPADSLVGDEDAGLLQLFAGLNPERIMTAAFAIGMGRYALARAVDYATTRQVWKLPIGGHQAIAHPLAQAHIELELARLMMQKAAALYDAGDDIGAGEAANMAKYAAAEACVKAVDQAVHTLGGNGLTREYGLAPLITAARVARIAPVSREMILNYVSHQSLGLPKSY
>CP032698.1|AYG82156.1|4814834_4815965_-|hypothetical-protein
MSGLRVEVCTEELAFADLAPNWRALHRRCSAATPFQSHAWLHSWWLSYGTPGRLRIHLVYRGDELVGAAPLMRVWRPLPALVPLGGAISDFTDVLLDDDCAEEAAAALTGVLIGSARSALIDFGEVRPGAGAERIHANWPGKRRTLTDSGCMELPAAGMDTILAALPSSRAQRVRAKLRKIDALGIEQREVPADDVPGALRTLLALHGLQWQGRGVTREHTRPRFEQHLTRAVSEMTRHGDAVVTEFRLDGQIVACDLTVLSPALAGAYLYGVHPALRDRKVDVATMLLRTNAQRLEGSGRGALSLLRGSEPYKQHWRPELVVNQRFLLARRRTLPLLWASTLHALLRRRAGAVRRELRRRRDERRRPAPERSGPA
>CP032698.1|AYG82157.1|4815964_4816636_-|hypothetical-protein
MSPISGSRQRQRSRGPLRTRWLPRWWPLPVCALLGATAGGVYGAVKTPEYSATSYVVVTPAEKADPSVALGFAQAYGRVATEVAVIGDAQVWAGVSADTLRRSVQTATSPDAPMIAITATSERAADAAGMANAVARALTLDGVHSQKDTGVRVVQFSRAAKPVAPSSPTASLTALVGGCAGGLLGGLSLLARPRRHEEPGTGPERVAAVPGPAGSACVPQEVG
>CP032698.1|AYG82158.1|4816632_4817874_-|D-inositol-3-phosphate-glycosyltransferase
MKVLHVITGLGIGGAEQQLRLLLRHLPYEADVVTLTNPGAVARAIVREGGRVRNLDMAGNRDLSALPRLTRLIAQGHYDLVHTHLYRACLYGRLAAKLARVRTIVATEHSLGETRMEGRRLGPAVRGLYLASERLGTTTVAVSDTIARRLTDWGVPEHRVQVVPNGIDAARFAFDPRTREKVRRTLGLPPRAFVIGGVGRLTAGKRFHTLIDALAELPHAMLVLAGTGEQEQPLRARADRLGLADRVVFVGECVQDGTAPAGHRPTLAGLLCAVDCLASPSGEESFGLAVVEGLAAGLPVAYVTCPAIDDLPPGSAPGALRTGRTAAAFADALGELQRSGRRLRQPVPDAVRHYSVTSTSAQLVRVYETAAERAPRRPAARPAPDARATGPAGHPPAGATDIPTNLSEKEESR
>CP032698.1|AYG82159.1|4817870_4818572_-|Poly-beta-1,6-N-acetyl-D-glucosamine-N-deacetylase
MYHSVTHTTDDPYRITVSPPRFERQLRWLRGHGLKGVSVAELLRARAAGTARGLVGLTFDDGYADFTAEALALLRRYDCTATVFVLPGLLGGANDWDPLGPRRPLLDERGIQRAATWGMEVASHGLRHLDLTHVDEDTLHREVRDSRQLLRDLTGHDVAGFCYPYGAVDLRAVAAVRAAGYRYACAIDPGPLTGRYALPRVHVGERDNGWRLHLKRSLHRWRREEPADLPEGS
>CP032698.1|AYG82160.1|4818645_4820262_-|putative-lipid-II-flippase-MurJ
MTETVPPLLPAPAAPPEPAASGRLLARAAFLTAVLTVAGAVLGLLRDQAFAHVFGAGADTDAFLVSWTVPEVAATLLIEDGLAFVLVPAFSLALVRRARHPDPDPVRALVAATLPRLMFALTGGAAVLICAAPAVVAVLAPSLPRADLAVDCTRATATCVLSFGLAGYCSAALRGHGRFLAPASIYVAYNVGIIGLLLLLGRAWGVRAAAAGVAFGGVLMVLVQVPALWRGWRRREAVPALPAARGPAGKTPRALRFALVAPVVVFALSRQTQVLIERFLAAPLPAGAISHLNYAQKVAQMPMVLSLMLCTVTFPVIARALAAGDTERARRRVESDLIVAGTIVLLGASVVVACAPEIIQLLFQRGAFTAHDTAATAAVMRVYALGLLGQTLVGVLARSYFSEARPLWFPACAMLAGLTATAVAGALAVPAWGAPGIAAANALGITLTALLLLWGSGRRRTALSVGPVSGQLVRLLGAACVATAACRWGASASSSPLFALVIGASVAVVVFAVTARLLRVREFCLLFRPVTRKLWHAR
>CP032698.1|AYG82161.1|4820258_4821593_-|hypothetical-protein
MHAVTAASPMPLPLPLPIRFGRALHLLPLLAVIALLATPPLGGDGSATAADAACGLLVVWAILRVVRSGERPLSRRAALVMGLPVTGICVAAMGAADPSTAIAGLGRYLQIFVLVPLAVLLLLRDRHDFRVAAGAVVALALFEGGIGVQQYLTSTGASYMGEDIRAVGTFGASDIMGMATVVSCGLLCAVALALDPAPGASRVTRRVALGCAALLLLPLAVSFSRGAWIATTVAACTVLLLSGVRRSLVVLAVVAAATVVLVGASGSGTRMLQERLASITQVESAPDQSVTDRYTMWAAAELMWRQQPLGGVGLKGFPAHRDAHSSLALSSGSDTAGAGAAFKRQPLLSPHNMYLLVLSEQGLIGVVTLVGGWAALLVTGVRALHRARRQRAPMDCGLVALGLLTWLLVDFFYGDIGGPSTALTALVLGLAAWWGLASRGEGRP
>CP032698.1|AYG82162.1|4821595_4823080_-|UDP-glucose:undecaprenyl-phosphate-glucose-1-phosphate-transferase
MTAESIVPSAGGPPHGAGMSTGTVSVVTPREAPDHFVPPAGRPRAGGTFVSVLLAVDCAAGLLGMLALPYAGLPPGPAGLLVATVLLLNAQAGLYRPTMTGGVLGDVPALLVRASAGWCVLAAVLAHRSVLAERGDMPLAVSAVIAGCAVQTVASCAGRGGALWLRRRKSARRPRPALVVGPAATAVRVTAALVRQAGGGVRPVGVVVPPSEAAVEAGPVPVLRSYEEVQRAVVQNGVRDCLFTYAVEAGGPSPASPALLEALGCALWQLDTRAPGHTVPGGQVDELAAFPCSPLTSTPAGAFGLFAKRLLDLALTVPALIVASPVLLVCALVLRRSDGPGVLFRQERIGAGGTTFTLLKFRTLRPDTVHEAATRWNIADDHRMSRAGHFMRRTSLDELPQLWNVIRGDMSLVGPRPERPYFVAQFSNAHPGYAARHRMPVGLTGLAQVEGLRGDTSIEDRARYDNYYIDHWSLWQDLCILLRTAACLVRPTGS
>CP032698.1|AYG82163.1|4823076_4824240_-|Putative-teichuronic-acid-biosynthesis-glycosyltransferase-TuaC
MPTRANAPGGPDGPPAHDLSVLHLVQPVEGGVARVVTDLVRDQLRSGFRVTVACPEGGPLSTELSRLGARVVPWRATRSPGPALLGETLRAARLIRRVRPDVIHAHSAKAGVAARLAARGRVPTVFQPHAWSFEAVGGITERLSRSWERAAVRWTSRVVCVSEGERATGERAGVLASFAVIPNGVDLDLYRAPGTARAATDAPLVVCVGRLCRQKGQDVLLRAWQDVRHAVPGAHLVLVGDGPDLAALRAAAPGSVSLIGAVSSTAAWYRAADLVVLPSRWEGMALAPLEAMACGTPVVVTDVGGSAESLPPGHAALCLVPPEDPGALARAITRLLTDAPLRTTLARQGLQHVTSTHDVRQTARSVAEVYRDVAVLPRSEHREPISQ
>CP032698.1|AYG82164.1|4824896_4825136_+|hypothetical-protein
MSRTAKALVMSTAAIATIAGGAGVAAADAGAQGAATNSPGVLSGNLLQVPVHVPVNVCGNTVNVIALLNPAFGNTCVNK
>CP032698.1|AYG82165.1|4825291_4826185_+|Levansucrase
MRARTPRRLAAVALSTAIVIATAGAAAAEGVQPPRPVAAEAAVPGSDEVLQQVKVLADLGGVLKPVTDLLTAALGGKSPAEITALASGATSALDAAKSATPAALVPAKPATPANPALPATPDKPATPANPAAVPATPANPATPANPALPATPAKPATPANPALPATPANPATPANPAAPAAPATSVRPVMPAAPVTPTSPALSALPLSGQPQAAGPVDVRADAVAVLKKSVDDLVKAVTSAKADGVVPAATSVVTGLVGLVVATLVGAGLPVPSLPGLPQPPKSPAGSLPAAPGLPA

Crispr_ID: CP032698_54

• CRISPR_ID: CP032698_54
• CRISPR_location: 4844282-4844380
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_54

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGGGG	CRISPRCasFinder

spacers of CP032698_54

>54.1|4844308|47|CP032698|CRISPRCasFinder
CCGAACCCTTCAATGCCCGTCACGGGCGGGTGGGTGGGAAAACGCGC

CRISPR arrays and Neighbor proteins around CP032698_54

CRISPR arrays

The CRISPR arrays of CP032698_54

>merge|CP032698|54|4844282-4844380|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGCCGAACCCTTCAATGCCCGTCACGGGCGGGTGGGTGGGAAAACGCGCCGGGGTCTGGGGCGGAGCCCCAGGGG

>CP032698|54|41|4844282-4844380|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGG	CCGAACCCTTCAATGCCCGTCACGGGCGGGTGGGTGGGAAAACGCGC
CGGGGTCTGGGGCGGAGCCCCAGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82189.1|4845999_4846824_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	unknown	unknown	gnl|CDD|224054
CP032698.1|AYG82194.1|4852570_4853017_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82180.1|4835909_4836119_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82190.1|4846891_4847575_-|hypothetical-protein	unknown	unknown	gnl|CDD|378140
CP032698.1|AYG82178.1|4834625_4835243_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82188.1|4844392_4846003_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82192.1|4849307_4850999_+|hypothetical-protein	unknown	unknown	gnl|CDD|223021
CP032698.1|AYG82196.1|4853973_4855383_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
CP032698.1|AYG82183.1|4838633_4839017_-|hypothetical-protein	unknown	unknown	gnl|CDD|380093
CP032698.1|AYG82186.1|4841845_4842538_+|Iron-dependent-repressor-IdeR	unknown	unknown	gnl|CDD|224240
CP032698.1|AYG82181.1|4836269_4837388_-|Putative-citrate-synthase-2	unknown	unknown	gnl|CDD|237070
CP032698.1|AYG82187.1|4843146_4844010_+|Tropinesterase	unknown	unknown	gnl|CDD|223669
CP032698.1|AYG82197.1|4855379_4855925_-|ECF-RNA-polymerase-sigma-factor-SigK	unknown	unknown	gnl|CDD|182015
CP032698.1|AYG82185.1|4840887_4841643_-|Phosphoheptose-isomerase	unknown	unknown	gnl|CDD|179510
CP032698.1|AYG82182.1|4837670_4838318_+|Pyridoxine/pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|273138
CP032698.1|AYG82193.1|4851035_4852397_-|hypothetical-protein	unknown	unknown	gnl|CDD|380564
CP032698.1|AYG82191.1|4847834_4849217_+|55.5-kDa-and-49.5-kDa-sporulation-proteins	unknown	unknown	unknown
CP032698.1|AYG82179.1|4835486_4835822_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82195.1|4853073_4853925_+|Formyltetrahydrofolate-deformylase	unknown	unknown	gnl|CDD|235676
CP032698.1|AYG82184.1|4839189_4840569_+|hypothetical-protein	unknown	unknown	gnl|CDD|225112

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82189.1|4845999_4846824_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.50186e-90
CP032698.1|AYG82192.1|4849307_4850999_+|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	6.57849e-11
CP032698.1|AYG82196.1|4853973_4855383_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	8.3526e-05
CP032698.1|AYG82183.1|4838633_4839017_-|hypothetical-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	1.66058e-29
CP032698.1|AYG82186.1|4841845_4842538_+|Iron-dependent-repressor-IdeR	gnl|CDD|224240	COG1321, TroR, Mn-dependent transcriptional regulator [Transcription].	3.21761e-46
CP032698.1|AYG82190.1|4846891_4847575_-|hypothetical-protein	gnl|CDD|378140	pfam09250, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal. Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities.	8.47081e-28
CP032698.1|AYG82187.1|4843146_4844010_+|Tropinesterase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	4.83578e-28
CP032698.1|AYG82197.1|4855379_4855925_-|ECF-RNA-polymerase-sigma-factor-SigK	gnl|CDD|182015	PRK09646, PRK09646, ECF RNA polymerase sigma factor SigK.	5.47132e-21
CP032698.1|AYG82185.1|4840887_4841643_-|Phosphoheptose-isomerase	gnl|CDD|179510	PRK02947, PRK02947, sugar isomerase domain-containing protein.	2.62248e-106
CP032698.1|AYG82182.1|4837670_4838318_+|Pyridoxine/pyridoxamine-5'-phosphate-oxidase	gnl|CDD|273138	TIGR00558, Pyridoxine/pyridoxamine_5'-phosphate_oxidase, pyridoxamine-phosphate oxidase. This model is similar to Pyridox_oxidase from Pfam but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	1.59878e-114
CP032698.1|AYG82193.1|4851035_4852397_-|hypothetical-protein	gnl|CDD|380564	cd06341, PBP1_ABC_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.	3.50094e-31
CP032698.1|AYG82181.1|4836269_4837388_-|Putative-citrate-synthase-2	gnl|CDD|237070	PRK12350, PRK12350, citrate synthase 2; Provisional.	0
CP032698.1|AYG82195.1|4853073_4853925_+|Formyltetrahydrofolate-deformylase	gnl|CDD|235676	PRK06027, purU, formyltetrahydrofolate deformylase; Reviewed.	0
CP032698.1|AYG82184.1|4839189_4840569_+|hypothetical-protein	gnl|CDD|225112	COG2202, AtoS, FOG: PAS/PAC domain [Signal transduction mechanisms].	1.6239e-12

Protein sequences

>CP032698.1|AYG82187.1|4843146_4844010_+|Tropinesterase
MVRRIDVTGAGGVRLAAWEFGDRPKARAETEPAPGVLLLHGLMGRASHWASTARWLTEKHRAVALDQRGHGRSEKPAEGPFTREVYVADAEAAVEQLGLAPVTLIGHSMGALTAWQLAAKRPDLVRALVICDMRASALGAASQREWEDWFTSWPLPFATLADVRKWFGEDDPWVERPSPARGEFFAEVMAERADGWRPVFSRRQMLRSRETWVYDAHWEELAQVTCPALVVRGLDGELGRAEAQEMVRVLPRGRYGEVADAGHLVHYDQPEGWRATLEPFLNLAPTP
>CP032698.1|AYG82186.1|4841845_4842538_+|Iron-dependent-repressor-IdeR
MSGLIDTTEMYLRTILELEEEGVVPMRARIAERLDQSGPTVSQTVARMERDGLVQVAGDRHLELTDEGRRLATRVMRKHRLAECLLVDVIGLEWEQVHAEACRWEHVMSEAVERRVLELLRHPTESPYGNPIPGLEELGEKAEADAFLEDGIISLGEFDPGPEGKTVIVRRIGEPIQTDAQLMYTLRRAGVQPGSVVSVTQSPGGVLVGSSGEAAELGADVASHVFVAKR
>CP032698.1|AYG82185.1|4840887_4841643_-|Phosphoheptose-isomerase
MSESKLAGQFFDAAIELLGRARDEESLNIAAAGAVIADAVEAGGRLFAFGAGHSSLAAQDVVYRAGGFALMNLLAVPGVVGVDVMPATLGSALERVDGLAGAVLDSSPARPGDVLVIISLSGRNALPVEMAMNARALGLKVIGVTSVAYAENTRSRHVSGTFLRDHCDIVLDSKIAVGDAELTHEGIEAPFAPASTVVTSALMQATMAAAAESLVARGVEPPLLRSGNVDGGHEWNGRVMAEYGDRIFFRH
>CP032698.1|AYG82184.1|4839189_4840569_+|hypothetical-protein
MSASRSETASAAVPDGSGSGTGSASEAGPEPGGGLLAALLDGMDAALCAFDADGVVTHWNREAERILGWPAEEAVGRHGFAGWAVRAADAEEIHGRLMAVMDAPGRQVHEFALLRKDGSRVLVRTQSAGVRGADGAPGGVYCAFSEVHAQIDLERSIALSEALAEDGTWGVVLVDVDLRPTVVNSYAARALGTGRSTLLGRPFGELIVQGVEELESALQHVLAEGAPAAPAEMWVTLRTPEGERRRCWRSGFLRLSSPLAEEPVPLGVGWLFQDVTDAKLAEQDADRLRFRSNQLHRASRAAAEYEDPMEAVACHLDFALAGFADHALVDLAVGDRLVRAVATPVGSPGPAAPVAAGGLPVRYPAGHPALQAVDRIGSVRASAGAGAARAEGWASERQWPPDAAHALCAVLRSRGRTLGVLTFLRGGARPGFERADAVYAESVGVRVGVVLDLAATLGA
>CP032698.1|AYG82183.1|4838633_4839017_-|hypothetical-protein
MTSLVRHVTFDCADAYRLATFWAQVLGGTLGEDDVPGDPEAQVTADGIALLFLVVPEPKAVKNRVHLDLQPQDRTRDEEVVRLLALGATLVDDHRRPDGTGWALMTDIEGNEFCVERSAEERARTSK
>CP032698.1|AYG82182.1|4837670_4838318_+|Pyridoxine/pyridoxamine-5'-phosphate-oxidase
MTDLDPAAMREQYRTTLLAQEELAATPMGQFARWFKEAVAGGLHEPNAMVVATATPDGRPSTRTVLLKSYDEHGFVFFTNYASRKAAELTANPYVSLLFPWHQLARQVIVTGTAARVPRAETERYFRSRPHGSRLGAWASDQSTVLASRAELAARYEELAARYPEGSDIPVPEHWGGFRVRPETVEFWQGHENRLHDRLRYVLRDGAWHVERLAP
>CP032698.1|AYG82181.1|4836269_4837388_-|Putative-citrate-synthase-2
MSDFVPGLEGVVAFETEIAEPDKEGGALRYRGVDIEDLVGHVSFGNVWGLLVDGAFNPGLPPAEPFPIPVHSGDIRVDVQSALAMLAPVWGLKPLLDIDEKTARDDLARAAVMALSYVAQSARGQGLPMVPQREIDKAQSVVERFMIRWRGEPDPKHVKAVDAYWTSAAEHGMNASTFTARVIASTGADVAAALSGAVGAMSGPLHGGAPSRVLGMIEEIERSGDASAYVKQALDKGERLMGFGHRVYRAEDPRARVLRRTAKELGAPRFEVAEALEKAALEELHARRPDRVLATNVEFWAAIVLDFAEVPAHMFTSMFSCARTAGWSAHILEQKRTGRLVRPSARYVGPGSRDPQSIEGYSDTLGVADFAG
>CP032698.1|AYG82180.1|4835909_4836119_-|hypothetical-protein
MSLIRRAAVVAALSAAVIVPTTATAQAAPQSAVRVVAHGNYGYGDDHGNNDSNRHRHYGLLTSLLLILL
>CP032698.1|AYG82179.1|4835486_4835822_+|hypothetical-protein
MAAVSLAATPRCAGVISTRRIATVLAVAAGVSGLAVSSANAAGPLDHVGKPLNPISELDNLAASGIPAQYAAQLPGVKQQLAGLNHLNDLSQLHQVIDPVQPLLGLLPVTG
>CP032698.1|AYG82178.1|4834625_4835243_+|hypothetical-protein
MSRPSGNVPATLRLAGAVAALLAVTALTAQGATAAAPGRPDPHPVGEGAPPWPAPADPAAAAKSAGLEMLSAEGMVQHTHTHLDVLVDGRPVTVPASIGIDAPHRLISPLHTHDTSGVIHVESPKRADFTLGQFMTEWGVPLSADRIGGLHAVGGRHLKAYVNGRAVAGNPAAIVLRERDEIALVLTRDTDTHPVPASYAWPNGL
>CP032698.1|AYG82188.1|4844392_4846003_-|hypothetical-protein
MTAPSPTTSALTPVFVRLKLSLLKNGLRQSGGRRAAYITSAVLALLFAALQLLGLIALRGNAHAATLTVLLVALLAIGWAVMPLFFPSGDETLDPTRLVMLPLRPRSMIGALLAASLVGIGPLFTLCLLLGSAIAVATRGVGAALVAVLAVPLALLVCVALARAVAAANTRLLTSRKGRDLAVLSGLVIAIGLQFVNFGAQRLGDAGGLSALDPAAEVVRWLPPSAAIGAVDSMSEGAYGRAAAQLLLCVAALGLLLYAWERSLVKLMTTPDGSTLAASDASRKESSGRGLASLLPEGRTGTVMLRTLRYAWRDPKTKAAWITSLAIGLIVPVFNALQGAGTVYFACFATGMLGMQMYNQFGQDTSAFWMVLLTISSTRDAYLELRARALALLLVTLPYTVLVAAVTAGMLGDWAKLPEVVGLALALLGAMLATGSVASATLAYAIPQDSRRNVAPGQGGIAALSILGGMVVSAVLCAPLIVLAVWLHVAGPHAGLWLLLPLGAAYGGLVCWVGLRVGAGRAVGRLPEILGAVSEG
>CP032698.1|AYG82189.1|4845999_4846824_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA
MPDQAFEGSSDTAGGALTAPPAVRVQGLWKRFGEQIAVAGIDLELPAGKFIGLVGPNGAGKTTTLSMVTGLLRPDQGRVEVGGHDVWRDPVAVKSRIGVLPEGLRLFERLSGRELLAYSGRLRGLPGAEVDKRAAQLLDVLDLAGSQHKLVVDYSTGMRKKIGLAAALLHNPQVLFLDEPFEGVDPVSAQIIRGVLERYTASGATVVFSSHVMELVESLCDWVAVMAAGRIRAQGTLAEVRGTAPTLQSAFLELVGASGRDTGDALDWLGGGAR
>CP032698.1|AYG82190.1|4846891_4847575_-|hypothetical-protein
MEETITGTDTEPAQIPKQRGEQLLDSAVRYAEERHWDVFPGTSLEPHEGVERCSCADTTCPKPGAHPARPDWATQATGSAVAARRLWSKNPRASILLPTGRTFDAIDVPESAGFLALARMERMDLTLGPVTCTPDRRMLFFVLPGAGAKVPDLVRKLGWSPAAVDLITRGEGDYVAAPPTRIGGSGAVQWARRPTPANRWLPDAEELISPLAYACGREAAAARGRRP
>CP032698.1|AYG82191.1|4847834_4849217_+|55.5-kDa-and-49.5-kDa-sporulation-proteins
MAARPLVARQPNERLQALIQEAGCSNAGLARRVNMVGAERGLDLRYDKTSVARWLRGQQPRGRAPGIIAEALGRKLGRTVTIDEIGMANGKNLASGVGLQFSPTVLGAIEQVCELWRSDVGRRDFLSGSTVAASALVEPSRDWLITGSDAQVARSAGQRVGAADVEAVKAMTDALVGLDHQFGAGHVRPVVVHYLNSVVSGLLAGSYRESVGRQLFAAVARLTELAGYMAVDTGQPGLAQRYYIQALRLAQAADDRGYGGYVLAASMSHLAAQLGNPREIAQLARAAQEGARGRVTPRAEAMFYAAEARGHALLGDARTCQIVAGRALTALEGADPESGDDPSWIAHFDHAYLADELAHCHRDLGQSEAAARRAEESLAGHPESRARRRAIGLILLATAQVQQREVEQACATGTRAAELLATLRTNRGADYLDDFQQRLEPYGDEPAVREFGERLEVQAA
>CP032698.1|AYG82192.1|4849307_4850999_+|hypothetical-protein
MTQRRQGDEPQLPAVRPAHEGVVLPADGSGPRAGEPLPAPPGAQPWGQPWGPQGQAAHRPPGAPPQGPATFGRPLPPENAGQDAEATQFIAPVPGGTGGPGGSGNEATQYLAVPGGPGGAGESGSEATQYLAVPGGPGGAGGSGSEATQYLAPVRGGNGGTDAEATRFIAPVPGGAGTYGGAAPHAGSFGGAAPQAGTYGGAAPQAGSFGGEATQYIAPVASGPGVLPPERAGEATRFPGAPASGQDADPTQFLPPVPPAPQDAPYGIRPGTPGERQPPAEFDSLFRADGPPQQAAEGAQLPRFQPSVPLSRPQQQTAYQPPGAPAPQFQAPPPYQEPPQQSGYEPEPPRRKSPVGLIAAVVVGCAVIGLGAGALLSGGGDDGKKDDKQPAGVSSAATGDTGGKTGDAADPAKTQAEALDKVLADSGSSRDAVIGAVADIRRCDKLDQAAASLRDAAKQRGDLVTRLGGLSLDKLPNRERLSGALTKAWQSSAAADNHYAAWADALAGDKGKNCKDGHAKRTKDAGLGDKASGDATKSKQEASVLWNAIATQYGLTKRGATQL
>CP032698.1|AYG82193.1|4851035_4852397_-|hypothetical-protein
MTGYGWQRTRGTTGPRRWISSCRTTTTVFAACSAVGASLLTGCGVLPGVAGGSREPITVMTWAPDGTSATNAPGMPALAKAFARWVNANGGLGGHELTVLTCNDHNTPVGASDCARRAVKEKAVAVVGSYSQYGSAFMPPLEVAGIPYLGGYGISDQEFTNALSYPVNGGQAALIAGSGRQLAQDCDQVSLVRPDTIAGDVLPTVLNAGLLDAHRAPAADIRTAEDAGDYTNEARRALAQAGADPALVSRIGRKAAEQKAHRGCVTAVLGDRTETFFDSFRRVESDGQKVRVASVIGSIGQPLLDRTGGKEGPFEGAYVTGWYPEADDPRWDPMKKVLREQAFGDNAIDAADAGVQTTWIAYTALKKVVESLGRDSVRAVDLVRALNSGVTVDTGGLTPELRWRFEDMLGAADFPRIVNRRVTFQVVREGRLVSLNKGFTDVSSTLEASAANG
>CP032698.1|AYG82194.1|4852570_4853017_+|hypothetical-protein
MGGMPLNDMPWWRWRTNVRSALHMLSDTVFHQETWLAGREGFGDVTDAVYRLVEDTWLDSWSAEKYVGTIFRDSGEAALVDLAVLRVLRIMHQVGADAPVSAYLAHHAWPEAVRAAREAHVRLAQNDGEDPDAPPRSLEVLSILTRST
>CP032698.1|AYG82195.1|4853073_4853925_+|Formyltetrahydrofolate-deformylase
MTDQYVLTLSCPDKQGIVHAVSSYLFITGCNIEDSQQFGDRDTGLFFMRVHFSAEAPVTVDKLRASFAAVGDAFQMEWGIHRPEERMRIVLMVSKFGHCLNDLLFRARSGALPVEIAAVVSNHTDFAELVASYGVPFHHIPVTKDTKAAAEARLVELVREERVELVVLARYMQVLSDDLCKELSGRIINIHHSFLPSFKGAKPYHQAHARGVKLIGATAHYVTADLDEGPIIEQEVKRVGHAVTPTQLVAIGRDVECQALARAVKWHAEHRILLNGRRTVVFA
>CP032698.1|AYG82196.1|4853973_4855383_-|hypothetical-protein
MSGPLEQGGQVPEDENTPRIPAPRAAGDDLTAGERDGGGPFVPAPREAGGAGPPAPARPGVPAPEPDAGPPSTPEPEPPSAAEPEVPVPEPVPQESAPLAGPPSHTVLKSLLGAWALAACSTEETDAVEAHLTECAPCADEALRLRDAVGLLQAERSLDLDPMLRARVLENCLGRRPARIPVPSWASPYDAEAARLDALLNDFGDAEWHAPVRLKWFEGERPTGRRTTVAGVIGHLMAVDALVATALGLDEPVPLDPEDAAGGPTARTEALWRAGQFPLTRSVREPWREQSHTLIRTVSFAGRGVAELAVEYGEFTLAMQDAMLDRAFECWIHAGDIAEAVDYPYAPPSGAHLHDMIDLAARSLPATLADRRRAGLASPPRGLVTAGSPGRSLRLEIEGVGGGDWLIALDSPAAVASPEHEVAHVALDGVEFCRLAAGHIPPQEAAVGQLGDREAISDVLFAAASLSRL
>CP032698.1|AYG82197.1|4855379_4855925_-|ECF-RNA-polymerase-sigma-factor-SigK
MQQRLARGEAAALGEFYDRFASLVHGLAARVLSDERAADQITREVFGYVWENPDAYDPKQGSMRSWVAKLTQREAVQRLRQAEASSHAESGGGSPEELELKVRRASAAARADYIVTSMPAPLRAALELAYFQRRDYRQAAADLSITEDEARRRLRLGLQLLSSANTRPPEGAAPPGYGRAL

Crispr_ID: CP032698_53

• CRISPR_ID: CP032698_53
• CRISPR_location: 4844058-4844215
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_53

Consensus_repeat	Method
TTTAGGGGCGCGGGGAACTGCGCGACCAGCCCCGCGCGGCC	PILER-CR

spacers of CP032698_53

>53.1|4844099|31|CP032698|PILER-CR
CCCTCTCGATCCTGCGGACCGTGCCCGCTTC
>53.2|4844171|24|CP032698|PILER-CR
CAAGAAAACCCGTCTTCGTCTGCG

CRISPR arrays and Neighbor proteins around CP032698_53

CRISPR arrays

The CRISPR arrays of CP032698_53

>merge|CP032698|53|4844058-4844215|PILER-CR
GGCCGCGGGTGGCTGGTCGCGCAGTTCCCCGCGCCCCTAAACCCTCTCGATCCTGCGGACCGTGCCCGCTTCTCGCGCAGTTCCCCGCGCCCCCAAGAAAACCCGTCTTCGTCTGCGGGCCGTGCGGGGCTGGGCGCGCAGTTCCCCGCGCCCCTTAA

>CP032698|53|15|4844058-4844215|PILER-CR
GGCCGCGGGTGGCTGGTCGCGCAGTTCCCCGCGCCCCTAAA	CCCTCTCGATCCTGCGGACCGTGCCCGCTTC
TCGCGCAGTTCCCCGCGCCCCCAAGAAAACCCGTCTTCGTC	TGCGGGCCGTGCGGGGCTGGGCGC
GCAGTTCCCCGCGCCCCTTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82189.1|4845999_4846824_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	unknown	unknown	gnl|CDD|224054
CP032698.1|AYG82194.1|4852570_4853017_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82180.1|4835909_4836119_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82190.1|4846891_4847575_-|hypothetical-protein	unknown	unknown	gnl|CDD|378140
CP032698.1|AYG82178.1|4834625_4835243_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82188.1|4844392_4846003_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82192.1|4849307_4850999_+|hypothetical-protein	unknown	unknown	gnl|CDD|223021
CP032698.1|AYG82196.1|4853973_4855383_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
CP032698.1|AYG82183.1|4838633_4839017_-|hypothetical-protein	unknown	unknown	gnl|CDD|380093
CP032698.1|AYG82186.1|4841845_4842538_+|Iron-dependent-repressor-IdeR	unknown	unknown	gnl|CDD|224240
CP032698.1|AYG82181.1|4836269_4837388_-|Putative-citrate-synthase-2	unknown	unknown	gnl|CDD|237070
CP032698.1|AYG82187.1|4843146_4844010_+|Tropinesterase	unknown	unknown	gnl|CDD|223669
CP032698.1|AYG82197.1|4855379_4855925_-|ECF-RNA-polymerase-sigma-factor-SigK	unknown	unknown	gnl|CDD|182015
CP032698.1|AYG82185.1|4840887_4841643_-|Phosphoheptose-isomerase	unknown	unknown	gnl|CDD|179510
CP032698.1|AYG82182.1|4837670_4838318_+|Pyridoxine/pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|273138
CP032698.1|AYG82193.1|4851035_4852397_-|hypothetical-protein	unknown	unknown	gnl|CDD|380564
CP032698.1|AYG82191.1|4847834_4849217_+|55.5-kDa-and-49.5-kDa-sporulation-proteins	unknown	unknown	unknown
CP032698.1|AYG82179.1|4835486_4835822_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82195.1|4853073_4853925_+|Formyltetrahydrofolate-deformylase	unknown	unknown	gnl|CDD|235676
CP032698.1|AYG82184.1|4839189_4840569_+|hypothetical-protein	unknown	unknown	gnl|CDD|225112

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82189.1|4845999_4846824_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.50186e-90
CP032698.1|AYG82192.1|4849307_4850999_+|hypothetical-protein	gnl|CDD|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	6.57849e-11
CP032698.1|AYG82196.1|4853973_4855383_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	8.3526e-05
CP032698.1|AYG82183.1|4838633_4839017_-|hypothetical-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	1.66058e-29
CP032698.1|AYG82186.1|4841845_4842538_+|Iron-dependent-repressor-IdeR	gnl|CDD|224240	COG1321, TroR, Mn-dependent transcriptional regulator [Transcription].	3.21761e-46
CP032698.1|AYG82190.1|4846891_4847575_-|hypothetical-protein	gnl|CDD|378140	pfam09250, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal. Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities.	8.47081e-28
CP032698.1|AYG82187.1|4843146_4844010_+|Tropinesterase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	4.83578e-28
CP032698.1|AYG82197.1|4855379_4855925_-|ECF-RNA-polymerase-sigma-factor-SigK	gnl|CDD|182015	PRK09646, PRK09646, ECF RNA polymerase sigma factor SigK.	5.47132e-21
CP032698.1|AYG82185.1|4840887_4841643_-|Phosphoheptose-isomerase	gnl|CDD|179510	PRK02947, PRK02947, sugar isomerase domain-containing protein.	2.62248e-106
CP032698.1|AYG82182.1|4837670_4838318_+|Pyridoxine/pyridoxamine-5'-phosphate-oxidase	gnl|CDD|273138	TIGR00558, Pyridoxine/pyridoxamine_5'-phosphate_oxidase, pyridoxamine-phosphate oxidase. This model is similar to Pyridox_oxidase from Pfam but is designed to find only true pyridoxamine-phosphate oxidase and to ignore the related protein PhzG involved in phenazine biosynthesis. This protein from E. coli was characterized as a homodimer with two FMN per dimer. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine].	1.59878e-114
CP032698.1|AYG82193.1|4851035_4852397_-|hypothetical-protein	gnl|CDD|380564	cd06341, PBP1_ABC_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.	3.50094e-31
CP032698.1|AYG82181.1|4836269_4837388_-|Putative-citrate-synthase-2	gnl|CDD|237070	PRK12350, PRK12350, citrate synthase 2; Provisional.	0
CP032698.1|AYG82195.1|4853073_4853925_+|Formyltetrahydrofolate-deformylase	gnl|CDD|235676	PRK06027, purU, formyltetrahydrofolate deformylase; Reviewed.	0
CP032698.1|AYG82184.1|4839189_4840569_+|hypothetical-protein	gnl|CDD|225112	COG2202, AtoS, FOG: PAS/PAC domain [Signal transduction mechanisms].	1.6239e-12

Protein sequences

>CP032698.1|AYG82187.1|4843146_4844010_+|Tropinesterase
MVRRIDVTGAGGVRLAAWEFGDRPKARAETEPAPGVLLLHGLMGRASHWASTARWLTEKHRAVALDQRGHGRSEKPAEGPFTREVYVADAEAAVEQLGLAPVTLIGHSMGALTAWQLAAKRPDLVRALVICDMRASALGAASQREWEDWFTSWPLPFATLADVRKWFGEDDPWVERPSPARGEFFAEVMAERADGWRPVFSRRQMLRSRETWVYDAHWEELAQVTCPALVVRGLDGELGRAEAQEMVRVLPRGRYGEVADAGHLVHYDQPEGWRATLEPFLNLAPTP
>CP032698.1|AYG82186.1|4841845_4842538_+|Iron-dependent-repressor-IdeR
MSGLIDTTEMYLRTILELEEEGVVPMRARIAERLDQSGPTVSQTVARMERDGLVQVAGDRHLELTDEGRRLATRVMRKHRLAECLLVDVIGLEWEQVHAEACRWEHVMSEAVERRVLELLRHPTESPYGNPIPGLEELGEKAEADAFLEDGIISLGEFDPGPEGKTVIVRRIGEPIQTDAQLMYTLRRAGVQPGSVVSVTQSPGGVLVGSSGEAAELGADVASHVFVAKR
>CP032698.1|AYG82185.1|4840887_4841643_-|Phosphoheptose-isomerase
MSESKLAGQFFDAAIELLGRARDEESLNIAAAGAVIADAVEAGGRLFAFGAGHSSLAAQDVVYRAGGFALMNLLAVPGVVGVDVMPATLGSALERVDGLAGAVLDSSPARPGDVLVIISLSGRNALPVEMAMNARALGLKVIGVTSVAYAENTRSRHVSGTFLRDHCDIVLDSKIAVGDAELTHEGIEAPFAPASTVVTSALMQATMAAAAESLVARGVEPPLLRSGNVDGGHEWNGRVMAEYGDRIFFRH
>CP032698.1|AYG82184.1|4839189_4840569_+|hypothetical-protein
MSASRSETASAAVPDGSGSGTGSASEAGPEPGGGLLAALLDGMDAALCAFDADGVVTHWNREAERILGWPAEEAVGRHGFAGWAVRAADAEEIHGRLMAVMDAPGRQVHEFALLRKDGSRVLVRTQSAGVRGADGAPGGVYCAFSEVHAQIDLERSIALSEALAEDGTWGVVLVDVDLRPTVVNSYAARALGTGRSTLLGRPFGELIVQGVEELESALQHVLAEGAPAAPAEMWVTLRTPEGERRRCWRSGFLRLSSPLAEEPVPLGVGWLFQDVTDAKLAEQDADRLRFRSNQLHRASRAAAEYEDPMEAVACHLDFALAGFADHALVDLAVGDRLVRAVATPVGSPGPAAPVAAGGLPVRYPAGHPALQAVDRIGSVRASAGAGAARAEGWASERQWPPDAAHALCAVLRSRGRTLGVLTFLRGGARPGFERADAVYAESVGVRVGVVLDLAATLGA
>CP032698.1|AYG82183.1|4838633_4839017_-|hypothetical-protein
MTSLVRHVTFDCADAYRLATFWAQVLGGTLGEDDVPGDPEAQVTADGIALLFLVVPEPKAVKNRVHLDLQPQDRTRDEEVVRLLALGATLVDDHRRPDGTGWALMTDIEGNEFCVERSAEERARTSK
>CP032698.1|AYG82182.1|4837670_4838318_+|Pyridoxine/pyridoxamine-5'-phosphate-oxidase
MTDLDPAAMREQYRTTLLAQEELAATPMGQFARWFKEAVAGGLHEPNAMVVATATPDGRPSTRTVLLKSYDEHGFVFFTNYASRKAAELTANPYVSLLFPWHQLARQVIVTGTAARVPRAETERYFRSRPHGSRLGAWASDQSTVLASRAELAARYEELAARYPEGSDIPVPEHWGGFRVRPETVEFWQGHENRLHDRLRYVLRDGAWHVERLAP
>CP032698.1|AYG82181.1|4836269_4837388_-|Putative-citrate-synthase-2
MSDFVPGLEGVVAFETEIAEPDKEGGALRYRGVDIEDLVGHVSFGNVWGLLVDGAFNPGLPPAEPFPIPVHSGDIRVDVQSALAMLAPVWGLKPLLDIDEKTARDDLARAAVMALSYVAQSARGQGLPMVPQREIDKAQSVVERFMIRWRGEPDPKHVKAVDAYWTSAAEHGMNASTFTARVIASTGADVAAALSGAVGAMSGPLHGGAPSRVLGMIEEIERSGDASAYVKQALDKGERLMGFGHRVYRAEDPRARVLRRTAKELGAPRFEVAEALEKAALEELHARRPDRVLATNVEFWAAIVLDFAEVPAHMFTSMFSCARTAGWSAHILEQKRTGRLVRPSARYVGPGSRDPQSIEGYSDTLGVADFAG
>CP032698.1|AYG82180.1|4835909_4836119_-|hypothetical-protein
MSLIRRAAVVAALSAAVIVPTTATAQAAPQSAVRVVAHGNYGYGDDHGNNDSNRHRHYGLLTSLLLILL
>CP032698.1|AYG82179.1|4835486_4835822_+|hypothetical-protein
MAAVSLAATPRCAGVISTRRIATVLAVAAGVSGLAVSSANAAGPLDHVGKPLNPISELDNLAASGIPAQYAAQLPGVKQQLAGLNHLNDLSQLHQVIDPVQPLLGLLPVTG
>CP032698.1|AYG82178.1|4834625_4835243_+|hypothetical-protein
MSRPSGNVPATLRLAGAVAALLAVTALTAQGATAAAPGRPDPHPVGEGAPPWPAPADPAAAAKSAGLEMLSAEGMVQHTHTHLDVLVDGRPVTVPASIGIDAPHRLISPLHTHDTSGVIHVESPKRADFTLGQFMTEWGVPLSADRIGGLHAVGGRHLKAYVNGRAVAGNPAAIVLRERDEIALVLTRDTDTHPVPASYAWPNGL
>CP032698.1|AYG82188.1|4844392_4846003_-|hypothetical-protein
MTAPSPTTSALTPVFVRLKLSLLKNGLRQSGGRRAAYITSAVLALLFAALQLLGLIALRGNAHAATLTVLLVALLAIGWAVMPLFFPSGDETLDPTRLVMLPLRPRSMIGALLAASLVGIGPLFTLCLLLGSAIAVATRGVGAALVAVLAVPLALLVCVALARAVAAANTRLLTSRKGRDLAVLSGLVIAIGLQFVNFGAQRLGDAGGLSALDPAAEVVRWLPPSAAIGAVDSMSEGAYGRAAAQLLLCVAALGLLLYAWERSLVKLMTTPDGSTLAASDASRKESSGRGLASLLPEGRTGTVMLRTLRYAWRDPKTKAAWITSLAIGLIVPVFNALQGAGTVYFACFATGMLGMQMYNQFGQDTSAFWMVLLTISSTRDAYLELRARALALLLVTLPYTVLVAAVTAGMLGDWAKLPEVVGLALALLGAMLATGSVASATLAYAIPQDSRRNVAPGQGGIAALSILGGMVVSAVLCAPLIVLAVWLHVAGPHAGLWLLLPLGAAYGGLVCWVGLRVGAGRAVGRLPEILGAVSEG
>CP032698.1|AYG82189.1|4845999_4846824_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA
MPDQAFEGSSDTAGGALTAPPAVRVQGLWKRFGEQIAVAGIDLELPAGKFIGLVGPNGAGKTTTLSMVTGLLRPDQGRVEVGGHDVWRDPVAVKSRIGVLPEGLRLFERLSGRELLAYSGRLRGLPGAEVDKRAAQLLDVLDLAGSQHKLVVDYSTGMRKKIGLAAALLHNPQVLFLDEPFEGVDPVSAQIIRGVLERYTASGATVVFSSHVMELVESLCDWVAVMAAGRIRAQGTLAEVRGTAPTLQSAFLELVGASGRDTGDALDWLGGGAR
>CP032698.1|AYG82190.1|4846891_4847575_-|hypothetical-protein
MEETITGTDTEPAQIPKQRGEQLLDSAVRYAEERHWDVFPGTSLEPHEGVERCSCADTTCPKPGAHPARPDWATQATGSAVAARRLWSKNPRASILLPTGRTFDAIDVPESAGFLALARMERMDLTLGPVTCTPDRRMLFFVLPGAGAKVPDLVRKLGWSPAAVDLITRGEGDYVAAPPTRIGGSGAVQWARRPTPANRWLPDAEELISPLAYACGREAAAARGRRP
>CP032698.1|AYG82191.1|4847834_4849217_+|55.5-kDa-and-49.5-kDa-sporulation-proteins
MAARPLVARQPNERLQALIQEAGCSNAGLARRVNMVGAERGLDLRYDKTSVARWLRGQQPRGRAPGIIAEALGRKLGRTVTIDEIGMANGKNLASGVGLQFSPTVLGAIEQVCELWRSDVGRRDFLSGSTVAASALVEPSRDWLITGSDAQVARSAGQRVGAADVEAVKAMTDALVGLDHQFGAGHVRPVVVHYLNSVVSGLLAGSYRESVGRQLFAAVARLTELAGYMAVDTGQPGLAQRYYIQALRLAQAADDRGYGGYVLAASMSHLAAQLGNPREIAQLARAAQEGARGRVTPRAEAMFYAAEARGHALLGDARTCQIVAGRALTALEGADPESGDDPSWIAHFDHAYLADELAHCHRDLGQSEAAARRAEESLAGHPESRARRRAIGLILLATAQVQQREVEQACATGTRAAELLATLRTNRGADYLDDFQQRLEPYGDEPAVREFGERLEVQAA
>CP032698.1|AYG82192.1|4849307_4850999_+|hypothetical-protein
MTQRRQGDEPQLPAVRPAHEGVVLPADGSGPRAGEPLPAPPGAQPWGQPWGPQGQAAHRPPGAPPQGPATFGRPLPPENAGQDAEATQFIAPVPGGTGGPGGSGNEATQYLAVPGGPGGAGESGSEATQYLAVPGGPGGAGGSGSEATQYLAPVRGGNGGTDAEATRFIAPVPGGAGTYGGAAPHAGSFGGAAPQAGTYGGAAPQAGSFGGEATQYIAPVASGPGVLPPERAGEATRFPGAPASGQDADPTQFLPPVPPAPQDAPYGIRPGTPGERQPPAEFDSLFRADGPPQQAAEGAQLPRFQPSVPLSRPQQQTAYQPPGAPAPQFQAPPPYQEPPQQSGYEPEPPRRKSPVGLIAAVVVGCAVIGLGAGALLSGGGDDGKKDDKQPAGVSSAATGDTGGKTGDAADPAKTQAEALDKVLADSGSSRDAVIGAVADIRRCDKLDQAAASLRDAAKQRGDLVTRLGGLSLDKLPNRERLSGALTKAWQSSAAADNHYAAWADALAGDKGKNCKDGHAKRTKDAGLGDKASGDATKSKQEASVLWNAIATQYGLTKRGATQL
>CP032698.1|AYG82193.1|4851035_4852397_-|hypothetical-protein
MTGYGWQRTRGTTGPRRWISSCRTTTTVFAACSAVGASLLTGCGVLPGVAGGSREPITVMTWAPDGTSATNAPGMPALAKAFARWVNANGGLGGHELTVLTCNDHNTPVGASDCARRAVKEKAVAVVGSYSQYGSAFMPPLEVAGIPYLGGYGISDQEFTNALSYPVNGGQAALIAGSGRQLAQDCDQVSLVRPDTIAGDVLPTVLNAGLLDAHRAPAADIRTAEDAGDYTNEARRALAQAGADPALVSRIGRKAAEQKAHRGCVTAVLGDRTETFFDSFRRVESDGQKVRVASVIGSIGQPLLDRTGGKEGPFEGAYVTGWYPEADDPRWDPMKKVLREQAFGDNAIDAADAGVQTTWIAYTALKKVVESLGRDSVRAVDLVRALNSGVTVDTGGLTPELRWRFEDMLGAADFPRIVNRRVTFQVVREGRLVSLNKGFTDVSSTLEASAANG
>CP032698.1|AYG82194.1|4852570_4853017_+|hypothetical-protein
MGGMPLNDMPWWRWRTNVRSALHMLSDTVFHQETWLAGREGFGDVTDAVYRLVEDTWLDSWSAEKYVGTIFRDSGEAALVDLAVLRVLRIMHQVGADAPVSAYLAHHAWPEAVRAAREAHVRLAQNDGEDPDAPPRSLEVLSILTRST
>CP032698.1|AYG82195.1|4853073_4853925_+|Formyltetrahydrofolate-deformylase
MTDQYVLTLSCPDKQGIVHAVSSYLFITGCNIEDSQQFGDRDTGLFFMRVHFSAEAPVTVDKLRASFAAVGDAFQMEWGIHRPEERMRIVLMVSKFGHCLNDLLFRARSGALPVEIAAVVSNHTDFAELVASYGVPFHHIPVTKDTKAAAEARLVELVREERVELVVLARYMQVLSDDLCKELSGRIINIHHSFLPSFKGAKPYHQAHARGVKLIGATAHYVTADLDEGPIIEQEVKRVGHAVTPTQLVAIGRDVECQALARAVKWHAEHRILLNGRRTVVFA
>CP032698.1|AYG82196.1|4853973_4855383_-|hypothetical-protein
MSGPLEQGGQVPEDENTPRIPAPRAAGDDLTAGERDGGGPFVPAPREAGGAGPPAPARPGVPAPEPDAGPPSTPEPEPPSAAEPEVPVPEPVPQESAPLAGPPSHTVLKSLLGAWALAACSTEETDAVEAHLTECAPCADEALRLRDAVGLLQAERSLDLDPMLRARVLENCLGRRPARIPVPSWASPYDAEAARLDALLNDFGDAEWHAPVRLKWFEGERPTGRRTTVAGVIGHLMAVDALVATALGLDEPVPLDPEDAAGGPTARTEALWRAGQFPLTRSVREPWREQSHTLIRTVSFAGRGVAELAVEYGEFTLAMQDAMLDRAFECWIHAGDIAEAVDYPYAPPSGAHLHDMIDLAARSLPATLADRRRAGLASPPRGLVTAGSPGRSLRLEIEGVGGGDWLIALDSPAAVASPEHEVAHVALDGVEFCRLAAGHIPPQEAAVGQLGDREAISDVLFAAASLSRL
>CP032698.1|AYG82197.1|4855379_4855925_-|ECF-RNA-polymerase-sigma-factor-SigK
MQQRLARGEAAALGEFYDRFASLVHGLAARVLSDERAADQITREVFGYVWENPDAYDPKQGSMRSWVAKLTQREAVQRLRQAEASSHAESGGGSPEELELKVRRASAAARADYIVTSMPAPLRAALELAYFQRRDYRQAAADLSITEDEARRRLRLGLQLLSSANTRPPEGAAPPGYGRAL

Crispr_ID: CP032698_55

• CRISPR_ID: CP032698_55
• CRISPR_location: 4866453-4866699
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP032698_55

Consensus_repeat	Method
GGGGCGCGGGGAACTGCGCG	PILER-CR

spacers of CP032698_55

>55.1|4866473|39|CP032698|PILER-CR
CCCAGCCACGCACGGTCCGCAGACGAAGACAGGTTTTCG
>55.2|4866532|34|CP032698|PILER-CR
ACCTGCCCCGTCCGGGCCAGCGCCGGTTCTGCTG
>55.3|4866586|37|CP032698|PILER-CR
AGAAGCGAGCACGGTCCGCACGTGACCGGGGGTTTTG
>55.4|4866643|37|CP032698|PILER-CR
GGAAGCGGGCACGGTGCGCACAAGACAGCGGGTTTCA

CRISPR arrays and Neighbor proteins around CP032698_55

CRISPR arrays

The CRISPR arrays of CP032698_55

>merge|CP032698|55|4866453-4866699|PILER-CR
GGGGCGCGGGGAACTGCGCGCCCAGCCACGCACGGTCCGCAGACGAAGACAGGTTTTCGGGGGCGCGGGGAACTGCGCGACCTGCCCCGTCCGGGCCAGCGCCGGTTCTGCTGGGGGCGCGGGGAACTGCGCGAGAAGCGAGCACGGTCCGCACGTGACCGGGGGTTTTGGGGGCGCGGGGAACTGCGCGGGAAGCGGGCACGGTGCGCACAAGACAGCGGGTTTCAGGGGCGCGGGGAACTGCGCG

>CP032698|55|16|4866453-4866699|PILER-CR
GGGGCGCGGGGAACTGCGCG	CCCAGCCACGCACGGTCCGCAGACGAAGACAGGTTTTCG
GGGGCGCGGGGAACTGCGCG	ACCTGCCCCGTCCGGGCCAGCGCCGGTTCTGCTG
GGGGCGCGGGGAACTGCGCG	AGAAGCGAGCACGGTCCGCACGTGACCGGGGGTTTTG
GGGGCGCGGGGAACTGCGCG	GGAAGCGGGCACGGTGCGCACAAGACAGCGGGTTTCA
GGGGCGCGGGGAACTGCGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82215.1|4874910_4875792_-|1,2-epoxyphenylacetyl-CoA-isomerase	unknown	unknown	gnl|CDD|235852
CP032698.1|AYG82216.1|4875840_4878066_-|hypothetical-protein	unknown	unknown	gnl|CDD|223972
CP032698.1|AYG82206.1|4864279_4865206_-|hypothetical-protein	unknown	unknown	gnl|CDD|377240
CP032698.1|AYG82209.1|4867906_4868956_+|Putative-alcohol-dehydrogenase-D	unknown	unknown	gnl|CDD|176240
CP032698.1|AYG82211.1|4870621_4871845_+|hypothetical-protein	unknown	unknown	gnl|CDD|340863
CP032698.1|AYG82214.1|4874234_4874825_-|Flavin-dependent-monooxygenase,-reductase-subunit-HsaB	unknown	unknown	gnl|CDD|214900
CP032698.1|AYG82208.1|4866770_4867910_+|Putative-acyl-CoA-dehydrogenase-FadE17	unknown	unknown	gnl|CDD|173841
CP032698.1|AYG82217.1|4879038_4880163_-|putative-oxidoreductase-CzcO	unknown	unknown	gnl|CDD|224983
CP032698.1|AYG82207.1|4865293_4866205_+|Putative-short-chain-type-dehydrogenase/reductase	unknown	unknown	gnl|CDD|187611
CP032698.1|AYG82205.1|4863506_4864028_+|hypothetical-protein	unknown	unknown	gnl|CDD|340413
CP032698.1|AYG82204.1|4862197_4863058_+|Acyl-CoA-dehydrogenase-FadE34	unknown	unknown	gnl|CDD|366103
CP032698.1|AYG82203.1|4861034_4862198_+|Putative-acyl-CoA-dehydrogenase-FadE17	unknown	unknown	gnl|CDD|173841
CP032698.1|AYG82198.1|4856172_4856547_+|Anti-sigma-B-factor-antagonist	unknown	unknown	gnl|CDD|132914
CP032698.1|AYG82199.1|4856616_4857147_+|Calerythrin	unknown	unknown	gnl|CDD|372618
CP032698.1|AYG82200.1|4857163_4858108_-|1-phosphatidylinositol-phosphodiesterase	unknown	unknown	gnl|CDD|176528
CP032698.1|AYG82210.1|4869315_4870347_-|HTH-type-transcriptional-regulator-CdhR	unknown	unknown	gnl|CDD|181818
CP032698.1|AYG82201.1|4858145_4859681_-|Short-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|341229
CP032698.1|AYG82212.1|4871977_4873285_+|putative-MFS-type-transporter-YhjX	unknown	unknown	gnl|CDD|340913
CP032698.1|AYG82202.1|4859806_4861006_+|hypothetical-protein	unknown	unknown	gnl|CDD|368185
CP032698.1|AYG82213.1|4873364_4874156_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82215.1|4874910_4875792_-|1,2-epoxyphenylacetyl-CoA-isomerase	gnl|CDD|235852	PRK06688, PRK06688, enoyl-CoA hydratase; Provisional.	5.99304e-71
CP032698.1|AYG82216.1|4875840_4878066_-|hypothetical-protein	gnl|CDD|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	4.12222e-99
CP032698.1|AYG82206.1|4864279_4865206_-|hypothetical-protein	gnl|CDD|377240	pfam04199, Cyclase, Putative cyclase. Proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form part of the active site.	1.8235e-16
CP032698.1|AYG82209.1|4867906_4868956_+|Putative-alcohol-dehydrogenase-D	gnl|CDD|176240	cd08279, Zn_ADH_class_III, Class III alcohol dehydrogenase. Glutathione-dependent formaldehyde dehydrogenases (FDHs, Class III ADH) are members of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. Class III ADH are also known as glutathione-dependent formaldehyde dehydrogenase (FDH), which convert aldehydes to corresponding carboxylic acid and alcohol. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of an beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.	8.76091e-159
CP032698.1|AYG82211.1|4870621_4871845_+|hypothetical-protein	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.25391e-39
CP032698.1|AYG82214.1|4874234_4874825_-|Flavin-dependent-monooxygenase,-reductase-subunit-HsaB	gnl|CDD|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	2.46551e-54
CP032698.1|AYG82208.1|4866770_4867910_+|Putative-acyl-CoA-dehydrogenase-FadE17	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	5.48764e-118
CP032698.1|AYG82217.1|4879038_4880163_-|putative-oxidoreductase-CzcO	gnl|CDD|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.85506e-45
CP032698.1|AYG82207.1|4865293_4866205_+|Putative-short-chain-type-dehydrogenase/reductase	gnl|CDD|187611	cd05353, hydroxyacyl-CoA-like_DH_SDR_c-like, (3R)-hydroxyacyl-CoA dehydrogenase-like, classical(c)-like SDRs. Beta oxidation of fatty acids in eukaryotes occurs by a four-reaction cycle, that may take place in mitochondria or in peroxisomes. (3R)-hydroxyacyl-CoA dehydrogenase is part of rat peroxisomal multifunctional MFE-2, it is a member of the NAD-dependent SDRs, but contains an additional small C-terminal domain that completes the active site pocket and participates in dimerization. The atypical, additional C-terminal extension allows for more extensive dimerization contact than other SDRs. MFE-2 catalyzes the second and third reactions of the peroxisomal beta oxidation cycle. Proteins in this subgroup have a typical catalytic triad, but have a His in place of the usual upstream Asn. This subgroup also contains members identified as 17-beta-hydroxysteroid dehydrogenases, including human peroxisomal 17-beta-hydroxysteroid dehydrogenase type 4 (17beta-HSD type 4, aka MFE-2, encoded by HSD17B4 gene) which is involved in fatty acid beta-oxidation and steroid metabolism. This subgroup also includes two SDR domains of the Neurospora crassa and Saccharomyces cerevisiae multifunctional beta-oxidation protein (MFP, aka Fox2). SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	8.21583e-76
CP032698.1|AYG82205.1|4863506_4864028_+|hypothetical-protein	gnl|CDD|340413	cd16936, HATPase_RsbW-like, Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains. This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.	4.01656e-17
CP032698.1|AYG82204.1|4862197_4863058_+|Acyl-CoA-dehydrogenase-FadE34	gnl|CDD|366103	pfam00441, Acyl-CoA_dh_1, Acyl-CoA dehydrogenase, C-terminal domain. C-terminal domain of Acyl-CoA dehydrogenase is an all-alpha, four helical up-and-down bundle.	3.97727e-22
CP032698.1|AYG82203.1|4861034_4862198_+|Putative-acyl-CoA-dehydrogenase-FadE17	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	8.29731e-165
CP032698.1|AYG82198.1|4856172_4856547_+|Anti-sigma-B-factor-antagonist	gnl|CDD|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	6.51772e-27
CP032698.1|AYG82199.1|4856616_4857147_+|Calerythrin	gnl|CDD|372618	pfam13499, EF-hand_7, EF-hand domain pair.	2.77869e-05
CP032698.1|AYG82200.1|4857163_4858108_-|1-phosphatidylinositol-phosphodiesterase	gnl|CDD|176528	cd08586, PI-PLCc_BcPLC_like, Catalytic domain of Bacillus cereus phosphatidylinositol-specific phospholipases C and similar proteins. This subfamily corresponds to the catalytic domain present in Bacillus cereus phosphatidylinositol-specific phospholipase C (PI-PLC, EC 4.6.1.13) and its sequence homologs found in bacteria and eukaryota. Bacterial PI-PLCs participate in Ca2+-independent PI metabolism, hydrolyzing the membrane lipid phosphatidylinositol (PI) to produce phosphorylated myo-inositol and diacylglycerol (DAG). Although their precise physiological function remains unclear, bacterial PI-PLCs may function as virulence factors in some pathogenic bacteria. Bacterial PI-PLCs contain a single TIM-barrel type catalytic domain. Their catalytic mechanism is based on general base and acid catalysis utilizing two well conserved histidines, and consists of two steps, a phosphotransfer and a phosphodiesterase reaction. This family also includes some uncharacterized eukaryotic homologs, which contains a single TIM-barrel type catalytic domain, X domain. They are similar to bacterial PI-PLCs, and distinct from typical eukaryotic PI-PLCs, which have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains, and strictly require Ca2+ for their catalytic activities. The prototype of this family is Bacillus cereus PI-PLC, which has a moderate thermal stability and is active as a monomer.	1.52305e-83
CP032698.1|AYG82210.1|4869315_4870347_-|HTH-type-transcriptional-regulator-CdhR	gnl|CDD|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	4.06623e-106
CP032698.1|AYG82201.1|4858145_4859681_-|Short-chain-fatty-acid--CoA-ligase	gnl|CDD|341229	cd05903, CHC_CoA_lg, Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase). Cyclohexanecarboxylate-CoA ligase activates the aliphatic ring compound, cyclohexanecarboxylate, for degradation. It catalyzes the synthesis of cyclohexanecarboxylate-CoA thioesters in a two-step reaction involving the formation of cyclohexanecarboxylate-AMP anhydride, followed by the nucleophilic substitution of AMP by CoA.	1.15756e-117
CP032698.1|AYG82212.1|4871977_4873285_+|putative-MFS-type-transporter-YhjX	gnl|CDD|340913	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters. This group is composed of uncharacterized bacterial MFS-type transporters including Bacillus subtilis YcxA and YbfB. YcxA has been shown to facilitate the export of surfactin in B. subtilis. The YcxA-like group belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.67145e-97
CP032698.1|AYG82202.1|4859806_4861006_+|hypothetical-protein	gnl|CDD|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	9.47119e-36
CP032698.1|AYG82213.1|4873364_4874156_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	2.85402e-07

Protein sequences

>CP032698.1|AYG82207.1|4865293_4866205_+|Putative-short-chain-type-dehydrogenase/reductase
MGNFLAGKVIAVTGAGRGIGRAVALAAAAEGARVVVNDYGVSIDGAEPSSEVADAVVKEILAAGGEAVAVADDVSTMAGGRHIVDTALARYGRIDGVVCVAGILRERMLFNMSEQEWDPVLATHLKGTFTVFRAASAVMRKQGSGTLIGFTSGNHQGSVAQANYSAAKGGIISLVRSAALGLHKYGVTANAVAPLARTRMSANVPMELKEMGSPEDVAALVVYLLSSRAHDEGITGQVYTIAGPKIAVWAQPRELRAGYAEGAWTPERIADFLPGTVGVDPMPMLAQLEAMARAASEGARPNA
>CP032698.1|AYG82206.1|4864279_4865206_-|hypothetical-protein
MSLPPEFHDIAKRVNNWGRWGSDDERGTLNHITDAVVREAVAEVRSGLRVPLALPLRQDGVQTGVIPGRINPLHTMVQINQEIFGPGTVACSDDAVTFGLQAATHWDALTHVSHSGRIYNGRPAATVTAHGGAEFSGIDTTGPVLARGVLLDVARAKGVDRLPGGHAVTPEDLDEAEEFAGVTVRAGDIVLVRTGQIQVYLAGDKPAYGYPSPGLSVRTPEWFHARDVAAVANDTLTFEIFPPEFEELWLPVHALDLVEMGMLQGQNWNLEALSTACAEAARHAFLLSAMPEPFVGATGTPVAPVAVL
>CP032698.1|AYG82205.1|4863506_4864028_+|hypothetical-protein
MQVLQVQLEVGPDPAEVGRARKWARSRLAGCGIGLDEPVAETLILLISELVTNAVVHTGCPAVLRMLLGPAEGGTVRVEVADRSCCPPKPRHALGDDTNGRGLELVDGLADRWGWRAEGVGKSIWCEVDRAAPGEPPAPERSGHSGLKECSGRTDGAYANETYDPPRAVTNTA
>CP032698.1|AYG82204.1|4862197_4863058_+|Acyl-CoA-dehydrogenase-FadE34
MDFQLAEEQRALKSGMRELLAARFDRDALRAAVDRPAVDRALWRALGEAGFFALRLSEKEGGVGLGLPEAALLFEEAGRALLPGPLVATHLAAREVPGAATGETVVTRVDGPLVAWLDQADLVQGDAVDATPIRSLDPLTPLHRTTGTRTDAPHEAVLLTAAEQLGSAARTTELAVQHARQRAQFGQAVGAFQAVKHLCADMLVRTEVARAAVYAAAVTGDPYEIAGAKLLADEAAVRCARDCLQVHGGMGFTWEADVHLHLKRAWVRSEQWQSAEQAAEALAAAL
>CP032698.1|AYG82203.1|4861034_4862198_+|Putative-acyl-CoA-dehydrogenase-FadE17
MDLTYTEEEEAFRAGLRTWLSRALPQLPPRPDPLDWPGRRAYDTTWQRMLYDAGYAGLHWPEEAGGRGATPTQHLIFLEETERAGAPYVGANFVGLLHAGPTIAAEGTPEQRARWLPPVLRGDEIWCQGFSEPDAGSDLAALRTRAVRDGDDYVVTGSKIWTSHAEVADWCELLVRTEPVSESVPKHRGITWLAMPMDAPGITVRPLRTLAGSTEFAEVFLDEVRVPAAHRVGAENDGWRVTMVTLSFERGTAFVGEVVACRRTLAELAAAAKANGRWDDATVRRQLGSLNAEFTALWRLTQWNVSAAGRGGGVPGVGGSVFKLRYSHARQELYDTAARVLGPDCLDLDRDWTLDRLSSLSYTIAAGTSQIQRNIVAERILGLPKGR
>CP032698.1|AYG82202.1|4859806_4861006_+|hypothetical-protein
MTELPRIVSVDDHVIEPAHLFDVWLPAKYRERGPRPLTAGIGELAYVAGKYQITMDPDGPPTDWWIYEDLKFPYKRNIAAVGFDRDEMTLEGITRAEMRRGCWDPKARLDDMDLNHVEASLCFPTFPRFCGQTFAEAHDKEVALACVRAYNDWMVEEWCGDSGGRLIPLCIVPLWDIDLAVAEIRRNAARGVRAVTFSEIPTHLGLPSIHCGYWDPFFAVCQETETVVNMHIGSSSQMPAASPDAPPAVQASLSFNNAMASMMDFLFSGVLVKFPTLKLAYSEGQMGWIPYALERADDVWEEHRAWGGVRDLIPEPPSTYYYRQIFCCFFRDKHGVASLDVVGRDNATFETDYPHVDSTFPHTKEVALDHMKGLDDETVHKLMRGNAIRMLGLDLDRSR
>CP032698.1|AYG82201.1|4858145_4859681_-|Short-chain-fatty-acid--CoA-ligase
MTGTAHALGSSRTLWELIERRAELTPDRPVLLQGDRVLTFGALRERCERVAAGLYGMGVRAGTVVAWQLPTRIETAVLSFALARLGAVQSPVIPYYREREVGFALRESKAEFFAVPGSWRGYDHTALAHRLGARGVFEAYGQLPEGDPGLLPPPPDDGTSVRWVYWTSGTTSDPKGVLHTDRSLIAGGSCLAHALRLTAADVGSMAFPFAHIAGPDYTVMLLLYGFPAVMFEHFALPDALAEYRRHKVTVAGGSTAFYSMFLAEQRKRPGEKVIPTLRLLAGGGAPKPPEIYHAVVREMGVQLTHGYGMTEVPMITMGSPDDTAENLATTEGCPPPGMEIRITDEAGRAVAPGLDGEVRLRGEAVCRGYLDRAQSEAAFDAEGFLVTGDVGHVKESGHLVLTGRIKDIIIRKGENISAKEIEDLLHTHPAVGDVAVIGLPDAERGELVCAVVEQPPGASELTLRALAAFLRAQGLSVHKVPERLEVVAALPRNEALRKVLKYKLRERFGGA
>CP032698.1|AYG82200.1|4857163_4858108_-|1-phosphatidylinositol-phosphodiesterase
MELTRRHLILGAAALSATALLPGAAPATAATRLSADPARWMAALPDSLSLLRMTIPGTHDSCCTDPNNGTEWSHTQNWGLTQQLQQGVRFFDIRANGLQGHLGDAFGIYHGAYYQGMTFGDVLVQSAAFLDSHPGEVLLMRLKKENGTNNDVGANFTDVLDVYLDQKGWRSRFLLTDRVPTLGEARGKIVLIAQFDNDWPVLQWPGGDNGFLSNQYIKLQDVYQGLSWPSKKTAKVTQQFDNAFYDQNSAQLYINFTSYAGGGWPKVNADAIMPGVQNYLTARLSERTHLGVVPMDFPDFHADTLRTLIDWNAH
>CP032698.1|AYG82199.1|4856616_4857147_+|Calerythrin
MDSMDSPESAAYERRVAARFASFDQDGNGWIDREDFSTAAAALLAEFSTTARCDKGQALYGGAEALWQGLAGIADVDGDQRVTRQEFVGGALKRLRDRTTGFTEIARPFLHAAFAVADTSGAGTVSVFDAERALRALGVSPAVAGDVAARLDRDADGRITEAEAVAAFAAYFTTMP
>CP032698.1|AYG82198.1|4856172_4856547_+|Anti-sigma-B-factor-antagonist
MTLRVDESEQGTWTVLRISGELDLVTAPRLRRQVHEAVAEGRRDLVLDLSGVQFCDSSGVGVLIAARRLMRSCQGRLRLILPARGALEGSHVNKVLAALGVRRLFEVYGDVGSAADESAEPLSA
>CP032698.1|AYG82208.1|4866770_4867910_+|Putative-acyl-CoA-dehydrogenase-FadE17
MEFHFNPQDTTFRQTARTWLTTHLAQQPPDWERELGKGGWIGIGWPDGTYGNRRATLTQQVVWAEEYARSAAPTRTGHIGENLLAPTLIAHGTLAQRARFLPPIARGEELWCQGYSEPGAGSDLAGIRTVARRDGDTYRITGQKIWISLAHEAHWCFVLARTEQGSRRHHGLSFLLVPMDQPGRIEVRPIRQLTGTSEFNEVFFDDARALADHVVGGEGNGWAVAMSLLALERGVSTLAQQIGFVGELERVVALAVAGGAVADPVLRARLVQQWAELKVMRWNALRTLGSSGEVGAPSVAKLLWGGWHRRLGELAMAVRGAAATAGPRDWTQDDPYALDPLQHLFLFSRADTIYGGSDEIQRTIIAERVLGLPREVRVP
>CP032698.1|AYG82209.1|4867906_4868956_+|Putative-alcohol-dehydrogenase-D
MRGVLFDGKQSQVVDDLEVRGPGPGEVLVAIAAAGLCHSDLSVIDGTIPFPVPVVLGHEGAGVVEEVGAGVTHVAPGDHVALSTLANCGACAECDRGRPTMCRKAIGMPGRPFSRGGAPVHQFASNSAFAERTLVKAVQAVKIPRDVPLTSAALIGCGVLTGVGAVLNRARVDIGDTVVVIGTGGIGLNVIQGARIAGASVIVAVDTNPAKEPLARQFGATHFLPSAEGARDILPNGADHAFECVGHPGLVRAAVDLLDRHGQAILLGMTAPTVEASFAPAALFLDKSILGCRYGSSRPQRDIPRYAELYRTGALLLDELVTRTYAVEDFTKAADDLHGGRVARGVLTF
>CP032698.1|AYG82210.1|4869315_4870347_-|HTH-type-transcriptional-regulator-CdhR
MNPNRADGHGGGGRRRGARAHRVVVIALDGIIPFELGIPQRIFGRAKDPADKTPLYEVLTCSVRAPGPVRTDADFAILTEHGPEALATADTVVIPASYELGPVFEEGVLTPELADALARVRPGTRMVSICTGGYVLAAGGYLDGRPATTHWASAEHFQRVFPTVRVDPEVLFIDDGDVLTSAGVAAGIDLCLHIVRRDHGSAVANEVARRTVVPPHRPGGQSQYIQRPLPEPRLASTTAARAWALGRLHEPIQLRDLAEQEAMSVRTFTRRFREEVGLSPGQWLTQQRVSHARHLLESTDLPVDAIARAAGFGTATSLRQHLQTTLGVPPTAYRRAFRSGAGG
>CP032698.1|AYG82211.1|4870621_4871845_+|hypothetical-protein
MPAAGAPPGRSALWSHDFRLFFTARTVAMFGDGMVPVALTAGLLGAGRPASSVGYALGAWMGPLAAFVLFGGVLADRFTPRRMMVIADALRLVGASVLAVSFLVVDGGPPLWEVYALSALSGVGAALFQPGVASTVPRIATDVQRANAVLGVSEALMGMAGPAFAGVVAGFWGAGAVFAANAATFGVSGVCLFLLKLRGGSASDVPRGGFFAELAGGWREFKARSWLWGVITIWTVYGLTVLGPATPLTAVLVTEGHGAGTYGALMAVNGAGSVAGGLLALRLRPARPLAAGAFALLGVSVALLSLGLDLPVLALGVGQFAVGAAFAFWLVMWSTTVQTHVPPEALNRLHAYDVAGSLLMLAAGRALAGPVAEAVGAEKVLLVGAGLNVVAVAVLLAVPAIGRLRRI
>CP032698.1|AYG82212.1|4871977_4873285_+|putative-MFS-type-transporter-YhjX
MTQTTHRPEAGPAPQHEAAPRIHRAWFVAAVAFVTIIGAAAFRSLPGLLIDPLHNEFHWSRGTIGAAVSVNLALYGLTAPFAAALMDRFGIRKVVAVALTVIAVGSGLTVFMHAAWQLLLYWGLLVGLGSGSMALAFAATVTNRWFTERRGLVTGVLTAASASGQLIFLPLLSWMVEAHGWRPAAVTVALAALAVVPFVWLLLRDHPADVGLAPYGATAFVPKPAPVPGAARRTLAVLAKAARTGPFWLLAGTFAICGASTNGLVQTHFVPSAHDHGMPVTAAAGLLAVIGVFDVVGTIFSGWLTDRFESRRLLATYYALRGVSLLFLPMLLAPTVHPPMVFFIVFYGLDWVATVPPTIALCRQHYGEDSAIVFGWVLASHQVGAAVVAFLGGVARDVFGSYDVVWYASGALCAAAALMALVIRRRGPAAEPLAL
>CP032698.1|AYG82213.1|4873364_4874156_+|hypothetical-protein
MNAQRQRRTKGAVWVTALLCAAATACGTARPGDPVAAAPAASSATVAAACGEGAGTDGTTGDGATRGAPGDPGGAGPATEDETGTPGPPADAEAGTPGPPTDAEAGTPGPPTDADPGTPGPPTDADPGTPGPPTDADPGTPGPPTDADPGAPGAPTDAGGGATACLPAGWFDMTRDFVDYYAGHRTKADDGMWPSVVAVRVHKAGGSERAVVTVNFTPPAGSSDWEGRRVAEVFADWRRDTYDDKGALRVETRGGVLITEASW
>CP032698.1|AYG82214.1|4874234_4874825_-|Flavin-dependent-monooxygenase,-reductase-subunit-HsaB
MAATVVRYLRSVGAATVAEPVEFLPRPDLRAVRDDERAPVDPGEFRRVLGGFASGVTVITAQDAAGPTGFACQSFASLSLDPPLVAFMVARTSTTWPRIARAGAFCVNVLGAEQGALCRGFAVSGADKFAGVDHDAAPATGSPRLHGAPAWIDCRVHAVHTGGDHLIVVGRVEALGATDDVAPLLFHRGRFGRFTD
>CP032698.1|AYG82215.1|4874910_4875792_-|1,2-epoxyphenylacetyl-CoA-isomerase
MDLTDPTDPSHSWVQHATDNGVSWITLNRPEALNALTPDQRERIISLLDAASADPAVRAVVITAVGKGFCAGADLRGAPAPAPAPDTTPAPASDAPPAPTPAAGQRVAGDVARTIRQGAQRLIAAVLDCEKPVIAAVNGTAAGLGAHLAFACDLILAAESARFIEVFVRRGLVPDGGGAYLLPRLVGPQRAKELMFFGDALGAADAARMGLVNRVVPDAELAATAKEWAERLATGPTRALALIKHLVNVSLDADRSAAFAAEAWAQEINMTTRDAQEGVAGFVARRTPKYRGL
>CP032698.1|AYG82216.1|4875840_4878066_-|hypothetical-protein
MLGSTHGTLTTDFRARVVACGEQPAPGAVHGRAAGEGDRDVSGRPLYRDVPDLDRFFRPESVAVVGASDAEGRPNTGITRRLIDWAERVGARIHPVHPTRTTVFGLPCVASVADLPEQVDLAVLLVGDPLPVVEELAEAKVKFAVAFASGFAETGERGAAAQERLAAAVKRSGLRLLGPNTNLNAFERFRDDLDGPAIALITQSGHQGRPVFTMQELGVRLSHWAPTGNEADLETADFISYFAEQPEVGAIACYVEGLKDGRAFLLAADRAARAGVPVVAVKVGRTETGARMAASHTGKLTGADDVVDAAMRQYGVIRVDGLDQLQDTAALLARARKPRAEGVVVYSISGGTGAHFSDLASAAGLPMPTLSPAKQAELHEWIPPYLDVANPVDNGGHPVGDWRGRKIIDAILADPSVGVLICPITGPFPPMSDKLAQDLVDAAEQTDKLVCVVWGSPLGTESAYRETLLGSDRVATFRTFANCIGAVRAYLSHHRFTTGYRSPFDEAPRVPSPSFRKAQALMRPGQQLSEHAAKQLLRAYGIRVPREQLVTSAAAAVRAAGLVGYPVVMKASGARLAHKSELGLVKVGLTSASQIRDAYRELTDIARYEDIDLDGVLVCQMVERGVEMVVGVTHDALFGPTVTVGLGGVLVEVLGDSAVRVPPFGEEQARDMLGELRGRALLDGVRGGPPLDVDALVEVVLRVQRMALELGDEIAELDINPLVVLPRGQGAVALDALAVCR
>CP032698.1|AYG82217.1|4879038_4880163_-|putative-oxidoreductase-CzcO
MADTSSPVSPVYVIGAGPGGLAVAAALGARGVRAVVLEKSDAVAASWRRHYDRLHLHTTRRLSSLPGLRIPRRFGRWVSRDDLVRYLEKYAEVHELEIVTGVEVERVERGPEGEGWVLYATGGRRLTTSAVVVATGYNHTPYVPDWAGAETYTGELLHASRYRDPAPYAGRDVLVVGAGNTGAEIAADLAEGEAARVRLAVRTPPHILRRSTAGWPAQATGILVRRLPVRLVDRAASVTERLSVPDLSAYGLPRPAGGLYSRVREGAIPVQDAGLIDAVRAGRVEPVAAVDSFDGAKVLLADGTRVSPEVVIAATGYRRGLEGLVGHLGVLDSRGRPRGRGVSGLYFTGFTNPISGMLRELRLDATRIAKSLTP

Crispr_ID: CP032698_56

• CRISPR_ID: CP032698_56
• CRISPR_location: 4878682-4878989
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of CP032698_56

Consensus_repeat	Method
GGGGCGCGGGGAACTGCGCGA	CRT

spacers of CP032698_56

>56.1|4878703|37|CP032698|CRT
GAAGCGGGCACGGTCCGCACACGACAGCGGGTTTTCA
>56.2|4878761|37|CP032698|CRT
CCAGCCACGCACGGTCTGCGGACGAAGACGGGCCTTG
>56.3|4878819|34|CP032698|CRT
GTAGCGAGCACGGTCCGCACATACCGGGGGTTTA
>56.4|4878874|38|CP032698|CRT
CCGGCCACCCACGGCCCGCAGGCGTGAACGGGTTTTCA
>56.5|4878933|36|CP032698|CRT
GACGCGGGTGCGGTTCGCAGGATCGGGAGGGGGTTG

CRISPR arrays and Neighbor proteins around CP032698_56

CRISPR arrays

The CRISPR arrays of CP032698_56

>merge|CP032698|56|4878682-4878989|CRT
GGGGCGCGGGGAACTGTGCGAGAAGCGGGCACGGTCCGCACACGACAGCGGGTTTTCAGGGGCGCGGGGAACTGCGCGACCAGCCACGCACGGTCTGCGGACGAAGACGGGCCTTGGGGGCGCGGGGAACTGCGCGAGTAGCGAGCACGGTCCGCACATACCGGGGGTTTAGGGGCGCGGGGAACTGCGCGACCGGCCACCCACGGCCCGCAGGCGTGAACGGGTTTTCAGGGGCGCGGGGAACTGCGCGGGACGCGGGTGCGGTTCGCAGGATCGGGAGGGGGTTGGGGGCGCGGGGAACTGCGCAA

>CP032698|56|6|4878682-4878989|CRT
GGGGCGCGGGGAACTGTGCGA	GAAGCGGGCACGGTCCGCACACGACAGCGGGTTTTCA
GGGGCGCGGGGAACTGCGCGA	CCAGCCACGCACGGTCTGCGGACGAAGACGGGCCTTG
GGGGCGCGGGGAACTGCGCGA	GTAGCGAGCACGGTCCGCACATACCGGGGGTTTA
GGGGCGCGGGGAACTGCGCGA	CCGGCCACCCACGGCCCGCAGGCGTGAACGGGTTTTCA
GGGGCGCGGGGAACTGCGCGG	GACGCGGGTGCGGTTCGCAGGATCGGGAGGGGGTTG
GGGGCGCGGGGAACTGCGCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82224.1|4885614_4886112_+|F420H(2)-dependent-quinone-reductase	unknown	unknown	gnl|CDD|211538
CP032698.1|AYG82223.1|4884430_4885618_+|(2S)-methylsuccinyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|224871
CP032698.1|AYG82217.1|4879038_4880163_-|putative-oxidoreductase-CzcO	unknown	unknown	gnl|CDD|224983
CP032698.1|AYG82215.1|4874910_4875792_-|1,2-epoxyphenylacetyl-CoA-isomerase	unknown	unknown	gnl|CDD|235852
CP032698.1|AYG82218.1|4880323_4880785_+|hypothetical-protein	unknown	unknown	gnl|CDD|225168
CP032698.1|AYG82220.1|4881307_4881880_+|Putative-ribosomal-N-acetyltransferase-YdaF	unknown	unknown	gnl|CDD|224584
CP032698.1|AYG82214.1|4874234_4874825_-|Flavin-dependent-monooxygenase,-reductase-subunit-HsaB	unknown	unknown	gnl|CDD|214900
CP032698.1|AYG82208.1|4866770_4867910_+|Putative-acyl-CoA-dehydrogenase-FadE17	unknown	unknown	gnl|CDD|173841
CP032698.1|AYG82219.1|4880781_4881267_+|hypothetical-protein	unknown	unknown	gnl|CDD|224462
CP032698.1|AYG82207.1|4865293_4866205_+|Putative-short-chain-type-dehydrogenase/reductase	unknown	unknown	gnl|CDD|187611
CP032698.1|AYG82211.1|4870621_4871845_+|hypothetical-protein	unknown	unknown	gnl|CDD|340863
CP032698.1|AYG82225.1|4886253_4886901_-|Nucleoid-occlusion-factor-SlmA	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG82216.1|4875840_4878066_-|hypothetical-protein	unknown	unknown	gnl|CDD|223972
CP032698.1|AYG82210.1|4869315_4870347_-|HTH-type-transcriptional-regulator-CdhR	unknown	unknown	gnl|CDD|181818
CP032698.1|AYG82226.1|4887302_4888094_+|Putative-glyoxylase-CFP32	unknown	unknown	gnl|CDD|319911
CP032698.1|AYG82221.1|4881932_4882583_-|Pyridoxine/pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl|CDD|235555
CP032698.1|AYG82213.1|4873364_4874156_+|hypothetical-protein	unknown	unknown	gnl|CDD|236090
CP032698.1|AYG82212.1|4871977_4873285_+|putative-MFS-type-transporter-YhjX	unknown	unknown	gnl|CDD|340913
CP032698.1|AYG82222.1|4883057_4884200_-|3-ketoacyl-CoA-thiolase	unknown	unknown	gnl|CDD|180434
CP032698.1|AYG82209.1|4867906_4868956_+|Putative-alcohol-dehydrogenase-D	unknown	unknown	gnl|CDD|176240

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82224.1|4885614_4886112_+|F420H(2)-dependent-quinone-reductase	gnl|CDD|211538	TIGR00026, Hypothetical_protein_Rv1261c/MT1299/Mb1292c., deazaflavin-dependent oxidoreductase, nitroreductase family. This model represents a family of proteins found in paralogous families in the genera Mycobacterium and Streptomyces. Seven members are in Mycobacterium tuberculosis. Member protein Rv3547 has been characterized as a deazaflavin-dependent nitroreductase. [Unknown function, Enzymes of unknown specificity].	1.6774e-21
CP032698.1|AYG82223.1|4884430_4885618_+|(2S)-methylsuccinyl-CoA-dehydrogenase	gnl|CDD|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	7.05839e-45
CP032698.1|AYG82217.1|4879038_4880163_-|putative-oxidoreductase-CzcO	gnl|CDD|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.85506e-45
CP032698.1|AYG82215.1|4874910_4875792_-|1,2-epoxyphenylacetyl-CoA-isomerase	gnl|CDD|235852	PRK06688, PRK06688, enoyl-CoA hydratase; Provisional.	5.99304e-71
CP032698.1|AYG82218.1|4880323_4880785_+|hypothetical-protein	gnl|CDD|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	0.00708752
CP032698.1|AYG82220.1|4881307_4881880_+|Putative-ribosomal-N-acetyltransferase-YdaF	gnl|CDD|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	4.52331e-24
CP032698.1|AYG82214.1|4874234_4874825_-|Flavin-dependent-monooxygenase,-reductase-subunit-HsaB	gnl|CDD|214900	smart00903, Flavin_Reduct, Flavin reductase like domain. This entry represents the FMN-binding domain found in NAD(P)H-flavin oxidoreductases (flavin reductases), a class of enzymes capable of producing reduced flavin for bacterial bioluminescence and other biological processes. This domain is also found in various other oxidoreductase and monooxygenase enzymes... This domain consists of a beta-barrel with Greek key topology, and is related to the ferredoxin reductase-like FAD-binding domain. The flavin reductases have a different dimerisation mode than that found in the PNP oxidase-like family, which also carries an FMN-binding domain with a similar topology.	2.46551e-54
CP032698.1|AYG82208.1|4866770_4867910_+|Putative-acyl-CoA-dehydrogenase-FadE17	gnl|CDD|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	5.48764e-118
CP032698.1|AYG82219.1|4880781_4881267_+|hypothetical-protein	gnl|CDD|224462	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only].	4.67808e-21
CP032698.1|AYG82207.1|4865293_4866205_+|Putative-short-chain-type-dehydrogenase/reductase	gnl|CDD|187611	cd05353, hydroxyacyl-CoA-like_DH_SDR_c-like, (3R)-hydroxyacyl-CoA dehydrogenase-like, classical(c)-like SDRs. Beta oxidation of fatty acids in eukaryotes occurs by a four-reaction cycle, that may take place in mitochondria or in peroxisomes. (3R)-hydroxyacyl-CoA dehydrogenase is part of rat peroxisomal multifunctional MFE-2, it is a member of the NAD-dependent SDRs, but contains an additional small C-terminal domain that completes the active site pocket and participates in dimerization. The atypical, additional C-terminal extension allows for more extensive dimerization contact than other SDRs. MFE-2 catalyzes the second and third reactions of the peroxisomal beta oxidation cycle. Proteins in this subgroup have a typical catalytic triad, but have a His in place of the usual upstream Asn. This subgroup also contains members identified as 17-beta-hydroxysteroid dehydrogenases, including human peroxisomal 17-beta-hydroxysteroid dehydrogenase type 4 (17beta-HSD type 4, aka MFE-2, encoded by HSD17B4 gene) which is involved in fatty acid beta-oxidation and steroid metabolism. This subgroup also includes two SDR domains of the Neurospora crassa and Saccharomyces cerevisiae multifunctional beta-oxidation protein (MFP, aka Fox2). SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	8.21583e-76
CP032698.1|AYG82211.1|4870621_4871845_+|hypothetical-protein	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.25391e-39
CP032698.1|AYG82225.1|4886253_4886901_-|Nucleoid-occlusion-factor-SlmA	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	9.07654e-10
CP032698.1|AYG82216.1|4875840_4878066_-|hypothetical-protein	gnl|CDD|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	4.12222e-99
CP032698.1|AYG82210.1|4869315_4870347_-|HTH-type-transcriptional-regulator-CdhR	gnl|CDD|181818	PRK09393, ftrA, transcriptional activator FtrA; Provisional.	4.06623e-106
CP032698.1|AYG82226.1|4887302_4888094_+|Putative-glyoxylase-CFP32	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	5.56839e-29
CP032698.1|AYG82221.1|4881932_4882583_-|Pyridoxine/pyridoxamine-5'-phosphate-oxidase	gnl|CDD|235555	PRK05679, PRK05679, pyridoxal 5'-phosphate synthase.	4.22455e-49
CP032698.1|AYG82213.1|4873364_4874156_+|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	2.85402e-07
CP032698.1|AYG82212.1|4871977_4873285_+|putative-MFS-type-transporter-YhjX	gnl|CDD|340913	cd17355, MFS_YcxA_like, MFS-type transporter YcxA and similar proteins of the Major Facilitator Superfamily of transporters. This group is composed of uncharacterized bacterial MFS-type transporters including Bacillus subtilis YcxA and YbfB. YcxA has been shown to facilitate the export of surfactin in B. subtilis. The YcxA-like group belongs to the Monocarboxylate transporter -like (MCT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.67145e-97
CP032698.1|AYG82222.1|4883057_4884200_-|3-ketoacyl-CoA-thiolase	gnl|CDD|180434	PRK06158, PRK06158, thiolase; Provisional.	2.17866e-134
CP032698.1|AYG82209.1|4867906_4868956_+|Putative-alcohol-dehydrogenase-D	gnl|CDD|176240	cd08279, Zn_ADH_class_III, Class III alcohol dehydrogenase. Glutathione-dependent formaldehyde dehydrogenases (FDHs, Class III ADH) are members of the zinc-dependent/medium chain alcohol dehydrogenase family. FDH converts formaldehyde and NAD(P) to formate and NAD(P)H. The initial step in this process the spontaneous formation of a S-(hydroxymethyl)glutathione adduct from formaldehyde and glutathione, followed by FDH-mediated oxidation (and detoxification) of the adduct to S-formylglutathione. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. Class III ADH are also known as glutathione-dependent formaldehyde dehydrogenase (FDH), which convert aldehydes to corresponding carboxylic acid and alcohol. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of an beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding.	8.76091e-159

Protein sequences

>CP032698.1|AYG82216.1|4875840_4878066_-|hypothetical-protein
MLGSTHGTLTTDFRARVVACGEQPAPGAVHGRAAGEGDRDVSGRPLYRDVPDLDRFFRPESVAVVGASDAEGRPNTGITRRLIDWAERVGARIHPVHPTRTTVFGLPCVASVADLPEQVDLAVLLVGDPLPVVEELAEAKVKFAVAFASGFAETGERGAAAQERLAAAVKRSGLRLLGPNTNLNAFERFRDDLDGPAIALITQSGHQGRPVFTMQELGVRLSHWAPTGNEADLETADFISYFAEQPEVGAIACYVEGLKDGRAFLLAADRAARAGVPVVAVKVGRTETGARMAASHTGKLTGADDVVDAAMRQYGVIRVDGLDQLQDTAALLARARKPRAEGVVVYSISGGTGAHFSDLASAAGLPMPTLSPAKQAELHEWIPPYLDVANPVDNGGHPVGDWRGRKIIDAILADPSVGVLICPITGPFPPMSDKLAQDLVDAAEQTDKLVCVVWGSPLGTESAYRETLLGSDRVATFRTFANCIGAVRAYLSHHRFTTGYRSPFDEAPRVPSPSFRKAQALMRPGQQLSEHAAKQLLRAYGIRVPREQLVTSAAAAVRAAGLVGYPVVMKASGARLAHKSELGLVKVGLTSASQIRDAYRELTDIARYEDIDLDGVLVCQMVERGVEMVVGVTHDALFGPTVTVGLGGVLVEVLGDSAVRVPPFGEEQARDMLGELRGRALLDGVRGGPPLDVDALVEVVLRVQRMALELGDEIAELDINPLVVLPRGQGAVALDALAVCR
>CP032698.1|AYG82215.1|4874910_4875792_-|1,2-epoxyphenylacetyl-CoA-isomerase
MDLTDPTDPSHSWVQHATDNGVSWITLNRPEALNALTPDQRERIISLLDAASADPAVRAVVITAVGKGFCAGADLRGAPAPAPAPDTTPAPASDAPPAPTPAAGQRVAGDVARTIRQGAQRLIAAVLDCEKPVIAAVNGTAAGLGAHLAFACDLILAAESARFIEVFVRRGLVPDGGGAYLLPRLVGPQRAKELMFFGDALGAADAARMGLVNRVVPDAELAATAKEWAERLATGPTRALALIKHLVNVSLDADRSAAFAAEAWAQEINMTTRDAQEGVAGFVARRTPKYRGL
>CP032698.1|AYG82214.1|4874234_4874825_-|Flavin-dependent-monooxygenase,-reductase-subunit-HsaB
MAATVVRYLRSVGAATVAEPVEFLPRPDLRAVRDDERAPVDPGEFRRVLGGFASGVTVITAQDAAGPTGFACQSFASLSLDPPLVAFMVARTSTTWPRIARAGAFCVNVLGAEQGALCRGFAVSGADKFAGVDHDAAPATGSPRLHGAPAWIDCRVHAVHTGGDHLIVVGRVEALGATDDVAPLLFHRGRFGRFTD
>CP032698.1|AYG82213.1|4873364_4874156_+|hypothetical-protein
MNAQRQRRTKGAVWVTALLCAAATACGTARPGDPVAAAPAASSATVAAACGEGAGTDGTTGDGATRGAPGDPGGAGPATEDETGTPGPPADAEAGTPGPPTDAEAGTPGPPTDADPGTPGPPTDADPGTPGPPTDADPGTPGPPTDADPGAPGAPTDAGGGATACLPAGWFDMTRDFVDYYAGHRTKADDGMWPSVVAVRVHKAGGSERAVVTVNFTPPAGSSDWEGRRVAEVFADWRRDTYDDKGALRVETRGGVLITEASW
>CP032698.1|AYG82212.1|4871977_4873285_+|putative-MFS-type-transporter-YhjX
MTQTTHRPEAGPAPQHEAAPRIHRAWFVAAVAFVTIIGAAAFRSLPGLLIDPLHNEFHWSRGTIGAAVSVNLALYGLTAPFAAALMDRFGIRKVVAVALTVIAVGSGLTVFMHAAWQLLLYWGLLVGLGSGSMALAFAATVTNRWFTERRGLVTGVLTAASASGQLIFLPLLSWMVEAHGWRPAAVTVALAALAVVPFVWLLLRDHPADVGLAPYGATAFVPKPAPVPGAARRTLAVLAKAARTGPFWLLAGTFAICGASTNGLVQTHFVPSAHDHGMPVTAAAGLLAVIGVFDVVGTIFSGWLTDRFESRRLLATYYALRGVSLLFLPMLLAPTVHPPMVFFIVFYGLDWVATVPPTIALCRQHYGEDSAIVFGWVLASHQVGAAVVAFLGGVARDVFGSYDVVWYASGALCAAAALMALVIRRRGPAAEPLAL
>CP032698.1|AYG82211.1|4870621_4871845_+|hypothetical-protein
MPAAGAPPGRSALWSHDFRLFFTARTVAMFGDGMVPVALTAGLLGAGRPASSVGYALGAWMGPLAAFVLFGGVLADRFTPRRMMVIADALRLVGASVLAVSFLVVDGGPPLWEVYALSALSGVGAALFQPGVASTVPRIATDVQRANAVLGVSEALMGMAGPAFAGVVAGFWGAGAVFAANAATFGVSGVCLFLLKLRGGSASDVPRGGFFAELAGGWREFKARSWLWGVITIWTVYGLTVLGPATPLTAVLVTEGHGAGTYGALMAVNGAGSVAGGLLALRLRPARPLAAGAFALLGVSVALLSLGLDLPVLALGVGQFAVGAAFAFWLVMWSTTVQTHVPPEALNRLHAYDVAGSLLMLAAGRALAGPVAEAVGAEKVLLVGAGLNVVAVAVLLAVPAIGRLRRI
>CP032698.1|AYG82210.1|4869315_4870347_-|HTH-type-transcriptional-regulator-CdhR
MNPNRADGHGGGGRRRGARAHRVVVIALDGIIPFELGIPQRIFGRAKDPADKTPLYEVLTCSVRAPGPVRTDADFAILTEHGPEALATADTVVIPASYELGPVFEEGVLTPELADALARVRPGTRMVSICTGGYVLAAGGYLDGRPATTHWASAEHFQRVFPTVRVDPEVLFIDDGDVLTSAGVAAGIDLCLHIVRRDHGSAVANEVARRTVVPPHRPGGQSQYIQRPLPEPRLASTTAARAWALGRLHEPIQLRDLAEQEAMSVRTFTRRFREEVGLSPGQWLTQQRVSHARHLLESTDLPVDAIARAAGFGTATSLRQHLQTTLGVPPTAYRRAFRSGAGG
>CP032698.1|AYG82209.1|4867906_4868956_+|Putative-alcohol-dehydrogenase-D
MRGVLFDGKQSQVVDDLEVRGPGPGEVLVAIAAAGLCHSDLSVIDGTIPFPVPVVLGHEGAGVVEEVGAGVTHVAPGDHVALSTLANCGACAECDRGRPTMCRKAIGMPGRPFSRGGAPVHQFASNSAFAERTLVKAVQAVKIPRDVPLTSAALIGCGVLTGVGAVLNRARVDIGDTVVVIGTGGIGLNVIQGARIAGASVIVAVDTNPAKEPLARQFGATHFLPSAEGARDILPNGADHAFECVGHPGLVRAAVDLLDRHGQAILLGMTAPTVEASFAPAALFLDKSILGCRYGSSRPQRDIPRYAELYRTGALLLDELVTRTYAVEDFTKAADDLHGGRVARGVLTF
>CP032698.1|AYG82208.1|4866770_4867910_+|Putative-acyl-CoA-dehydrogenase-FadE17
MEFHFNPQDTTFRQTARTWLTTHLAQQPPDWERELGKGGWIGIGWPDGTYGNRRATLTQQVVWAEEYARSAAPTRTGHIGENLLAPTLIAHGTLAQRARFLPPIARGEELWCQGYSEPGAGSDLAGIRTVARRDGDTYRITGQKIWISLAHEAHWCFVLARTEQGSRRHHGLSFLLVPMDQPGRIEVRPIRQLTGTSEFNEVFFDDARALADHVVGGEGNGWAVAMSLLALERGVSTLAQQIGFVGELERVVALAVAGGAVADPVLRARLVQQWAELKVMRWNALRTLGSSGEVGAPSVAKLLWGGWHRRLGELAMAVRGAAATAGPRDWTQDDPYALDPLQHLFLFSRADTIYGGSDEIQRTIIAERVLGLPREVRVP
>CP032698.1|AYG82207.1|4865293_4866205_+|Putative-short-chain-type-dehydrogenase/reductase
MGNFLAGKVIAVTGAGRGIGRAVALAAAAEGARVVVNDYGVSIDGAEPSSEVADAVVKEILAAGGEAVAVADDVSTMAGGRHIVDTALARYGRIDGVVCVAGILRERMLFNMSEQEWDPVLATHLKGTFTVFRAASAVMRKQGSGTLIGFTSGNHQGSVAQANYSAAKGGIISLVRSAALGLHKYGVTANAVAPLARTRMSANVPMELKEMGSPEDVAALVVYLLSSRAHDEGITGQVYTIAGPKIAVWAQPRELRAGYAEGAWTPERIADFLPGTVGVDPMPMLAQLEAMARAASEGARPNA
>CP032698.1|AYG82217.1|4879038_4880163_-|putative-oxidoreductase-CzcO
MADTSSPVSPVYVIGAGPGGLAVAAALGARGVRAVVLEKSDAVAASWRRHYDRLHLHTTRRLSSLPGLRIPRRFGRWVSRDDLVRYLEKYAEVHELEIVTGVEVERVERGPEGEGWVLYATGGRRLTTSAVVVATGYNHTPYVPDWAGAETYTGELLHASRYRDPAPYAGRDVLVVGAGNTGAEIAADLAEGEAARVRLAVRTPPHILRRSTAGWPAQATGILVRRLPVRLVDRAASVTERLSVPDLSAYGLPRPAGGLYSRVREGAIPVQDAGLIDAVRAGRVEPVAAVDSFDGAKVLLADGTRVSPEVVIAATGYRRGLEGLVGHLGVLDSRGRPRGRGVSGLYFTGFTNPISGMLRELRLDATRIAKSLTP
>CP032698.1|AYG82218.1|4880323_4880785_+|hypothetical-protein
MDSIWLSGAEWLAVLRIGLGLWWLESWRHKDKKGWFERGTGIAWASDVAAKHRWSAVRSGFDTVVKPRPKVMAYVVVYAELALGLGLVAGLLTPVALVCGLLLNLLYLVLMIHDWAEQGQNAMMALISLVALGAMAWQTWSLDDALGLFRWRT
>CP032698.1|AYG82219.1|4880781_4881267_+|hypothetical-protein
MNAATPDVDAFTRPYWDSAAQGRLLIRHCAACDRPHHYPREFCPYCWSEDVHWRPASGRATLYTWSVVHRNDLPPFGDRVPYVAAVVDLAEGPRMMTEVVGCPEADLRIGMELYVRFRGGAEGGVGAEDGVGAGGGVTVPVFGPAPVPVFGPAPVPGAGPV
>CP032698.1|AYG82220.1|4881307_4881880_+|Putative-ribosomal-N-acetyltransferase-YdaF
MKLQLIPADLRGHGLRLRVWRDNDVEPLLRGVTDPEYLRWNTHNAPVEDEAAVAELLRLRALGWARGEFATYCVTDESSGEVLGHVGLNSVDWPLRCARVGYWTLPEARGRGVAGHALELITRWAFDTVGLHRVELGHAVGHHVSCRVAERCGYRAEGTLRGAMFEAGRRDAFRDLHLHARLATDGGARE
>CP032698.1|AYG82221.1|4881932_4882583_-|Pyridoxine/pyridoxamine-5'-phosphate-oxidase
MEFREFLHTLRVWDTDLPPFTPDTAPPTPLPLFQQWLTHAATAGQPEPHTMSLATVDTEGNPDIRTLTLHDADDAGWHFGSHSTSAKGRQLAAHPVAALGFYWPVVGRQVRVRGHVTPSDPAVSQADLHARSTGALAAALVGRMSEVLADYAELEAAYADAWQRAEADPLTPVATWTRYVLDPTEVEFFQGDAQRRHVRLRYRREGSAWTRELLWP
>CP032698.1|AYG82222.1|4883057_4884200_-|3-ketoacyl-CoA-thiolase
MAVVGVALSDTGRVDDATPYALHAQAARRALADSGLDRGVIDGFASAGLGTLAPVGVAEYLGLRPTWVDSTTVGGATWEVMAAHAADAIAAGHANAVLLVYGSTARADIKAGRRTSNLSFGSRGPLQFEAPYGHTLISKYAMAARRHMHQYGTTIEQLASVAVQARANAATNPDAMFRDPITVDDVLSGPMIADPFTKLHCCIRSDGGCAVLLAAEEYVSDTIKAPVWVLGSGTAVSHTTMSEWEDFTVSPAAVSGRLAFERAGVRPADVDVVQIYDAFTYMTLVTLEDLGFCAKGEGGAFVEKGRLLRDGELPVNTDGGGLSACHPGMRGLFLVVEAVRQLRGEAGVGQVGRGRLPEVAVASGTGGWFCSSGTLVLGRG
>CP032698.1|AYG82223.1|4884430_4885618_+|(2S)-methylsuccinyl-CoA-dehydrogenase
MDATFTAEQDAIRRTLHELLVKHCGPQDVKNAVRTPAGYDGRLWGRLATELGLPGLALPEAYGGTGCTTADLALACEETGRALLPSPLLATAVLAAPLITALGTDAQKDALLPPIARGECGATLTVPGPGLALALGLTGVNTDGDWAGGGRAGGVQAGRTPQGAWRLYGEADQVLDGHSARLLIVAAHTGGFARGRTLLFLVPGDAEGLRRTRRTALDETRTQGRVQLRDVEAQLLGDDDCAPVGEALAAVGRTAAACLAAEAVGAAGEALERTVAYVKGREQFGRPIGSFQAVKHRLADLYVQVQAARSAAYYAAWDPGAGALALAQGLDALRAAASEAIQLHGGIGFTWEHEAHLYFKRAAADELLFGPVHRLRAHAAEQAGLFDPAAREVTV
>CP032698.1|AYG82224.1|4885614_4886112_+|F420H(2)-dependent-quinone-reductase
MNAGPATTAPGVRLMQKVSSTRAFARIAPHFVPAMDRAVHRLTRGRVILSARMLPGVVLTARGAKSGLARTTPLACMPEAGGDTWVLIGSNFGRPGHPAWTGNLLAHPDAEISWQGRDIAVRARLLEGEERAAVWQAALNFWPPYATYQSRIEREIRLFRLERRD
>CP032698.1|AYG82225.1|4886253_4886901_-|Nucleoid-occlusion-factor-SlmA
MTGQVRTVDGRVAGRRGQATRQKLLDCLSEMLSSSPYRDVKVIDVARKAGTSPATFYQYFPDVEGAVLEIAEEMAKEGAGLTALVEGRSWAGRAGWQTAEELVEGFLDFWRKNDAILRVVDLGAAEGDKRFYKIRMKILNSVTNSLTDAVTELQAKNKVDKDVSPAAMAGSLVAMLASVASHQKGFQTWGVKQAELRPNLALLVHLGITGKKPTK
>CP032698.1|AYG82226.1|4887302_4888094_+|Putative-glyoxylase-CFP32
MGGYPEGAPCWADVSLSDPAAGKRFYGELLGWTFDEGGADKQGHYTGAFKDGRRVAALQPKRDGRMPTTWTVYFATPDARALATRIREAGGQLITEPMPVPPHGTLAVAADPGGAVFGLWQGEAHTGFELTRVPGSFCWTEVYTRDKDQADAFYESVFGYRGTSPGSADELGADIRTWSLPGTEPGPDTAVGARSLMSDAFPAALPDHFLVYFLVEDCDATAAACTRLGGRVTAQPFDIRYGRMAVLNDNQGATFAVLQGSGT

Crispr_ID: CP032698_57

• CRISPR_ID: CP032698_57
• CRISPR_location: 4918269-4918347
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_57

Consensus_repeat	Method
GCCCGCGCAGTTCCCCGCGCCCC	CRISPRCasFinder

spacers of CP032698_57

>57.1|4918292|33|CP032698|CRISPRCasFinder
CCAACCCCCTGTCGTCTGCGGCCCGCGGTCGCT

CRISPR arrays and Neighbor proteins around CP032698_57

CRISPR arrays

The CRISPR arrays of CP032698_57

>merge|CP032698|57|4918269-4918347|CRISPRCasFinder
GCCCGCGCAGTTCCCCGCGCCCCCCAACCCCCTGTCGTCTGCGGCCCGCGGTCGCTGCTCGCGCAGTTCCCCGCGCCCC

>CP032698|57|42|4918269-4918347|CRISPRCasFinder
GCCCGCGCAGTTCCCCGCGCCCC	CCAACCCCCTGTCGTCTGCGGCCCGCGGTCGCT
GCTCGCGCAGTTCCCCGCGCCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82261.1|4930947_4932072_+|hypothetical-protein	unknown	unknown	gnl|CDD|377122
CP032698.1|AYG82256.1|4924110_4924638_-|hypothetical-protein	unknown	unknown	gnl|CDD|380345
CP032698.1|AYG82244.1|4906816_4907251_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82258.1|4925413_4927882_+|Beta-barrel-assembly-enhancing-protease	unknown	unknown	gnl|CDD|223533
CP032698.1|AYG82250.1|4912930_4914670_+|N-acyl-D-glutamate-deacylase	unknown	unknown	gnl|CDD|238622
CP032698.1|AYG82243.1|4905961_4906411_+|hypothetical-protein	unknown	unknown	gnl|CDD|239527
CP032698.1|AYG82259.1|4928181_4930548_+|putative-type-I-restriction-enzymeP-M-protein	unknown	unknown	gnl|CDD|280533
CP032698.1|AYG82260.1|4930592_4930805_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82251.1|4914666_4916142_+|Betaine-aldehyde-dehydrogenase	unknown	unknown	gnl|CDD|143408
CP032698.1|AYG82262.1|4932154_4932625_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82254.1|4919591_4921280_-|hypothetical-protein	unknown	unknown	gnl|CDD|334820
CP032698.1|AYG82246.1|4908041_4909250_+|Extracellular-serine-proteinase	unknown	unknown	gnl|CDD|173790
CP032698.1|AYG82253.1|4918673_4919504_+|Phthiodiolone/phenolphthiodiolone-dimycocerosates-ketoreductase	unknown	unknown	gnl|CDD|274680
CP032698.1|AYG82248.1|4910293_4911127_+|3-alpha-(or-20-beta)-hydroxysteroid-dehydrogenase	unknown	unknown	gnl|CDD|187600
CP032698.1|AYG82249.1|4911271_4912399_+|Alkanal-monooxygenase-alpha-chain	unknown	unknown	gnl|CDD|225052
CP032698.1|AYG82255.1|4921474_4924114_+|FO-synthase	unknown	unknown	gnl|CDD|236422
CP032698.1|AYG82245.1|4907405_4907687_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82247.1|4909356_4910301_+|Alkanesulfonate-monooxygenase	unknown	unknown	gnl|CDD|274680
CP032698.1|AYG82252.1|4916571_4918101_-|hypothetical-protein	unknown	unknown	gnl|CDD|213987
CP032698.1|AYG82257.1|4924759_4925380_+|hypothetical-protein	unknown	unknown	gnl|CDD|366102

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82261.1|4930947_4932072_+|hypothetical-protein	gnl|CDD|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	1.22361e-40
CP032698.1|AYG82256.1|4924110_4924638_-|hypothetical-protein	gnl|CDD|380345	cd02215, cupin_QDO_N_C, quercetinase, N- and C-terminal cupin domains. This family contains quercetinase (also known as quercetin 2,3-dioxygenase, 2,3QD, QDO and YxaG; EC 1.13.11.24), a mononuclear copper-dependent dioxygenase that catalyzes the cleavage of the flavonol quercetin (5,7,3',4'-tetrahydroxyflavonol) heterocyclic ring to produce 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. Bacillus subtilis quercetin 2,3-dioxygenase (QDO) is a homodimer that shows oxygenase activity with several divalent metals such as Mn2+, Co2+, Fe2+, and Cu2+, although the preferred one appears to be Mn2+. The dioxygen binds to the metal ion of the Cu-QDO-quercetin complex, yielding a Cu2+-superoxo quercetin radical intermediate, which then forms a Cu2+-alkylperoxo complex which then evolves into endoperoxide intermediate that decomposes to the product. Quercetinase is a bicupin with two tandem cupin beta-barrel domains, both of which are included in this alignment model. The pirins, which also belong to the cupin domain family, have been shown to catalyze a reaction involving quercetin and may have a function similar to that of quercetinase.	1.95183e-14
CP032698.1|AYG82258.1|4925413_4927882_+|Beta-barrel-assembly-enhancing-protease	gnl|CDD|223533	COG0457, NrfG, FOG: TPR repeat [General function prediction only].	9.69817e-21
CP032698.1|AYG82250.1|4912930_4914670_+|N-acyl-D-glutamate-deacylase	gnl|CDD|238622	cd01297, D-aminoacylase, D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics.	4.88639e-91
CP032698.1|AYG82243.1|4905961_4906411_+|hypothetical-protein	gnl|CDD|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.57222e-20
CP032698.1|AYG82259.1|4928181_4930548_+|putative-type-I-restriction-enzymeP-M-protein	gnl|CDD|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	1.04733e-52
CP032698.1|AYG82251.1|4914666_4916142_+|Betaine-aldehyde-dehydrogenase	gnl|CDD|143408	cd07089, ALDH_CddD-AldA-like, Rhodococcus ruber 6-oxolauric acid dehydrogenase-like and related proteins. The 6-oxolauric acid dehydrogenase (CddD) from Rhodococcus ruber SC1 which converts 6-oxolauric acid to dodecanedioic acid; and the aldehyde dehydrogenase (locus SSP0762) from Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 and also, the Mycobacterium tuberculosis H37Rv ALDH AldA (locus Rv0768) sequence; and other similar sequences, are included in this CD.	0
CP032698.1|AYG82254.1|4919591_4921280_-|hypothetical-protein	gnl|CDD|334820	pfam02129, Peptidase_S15, X-Pro dipeptidyl-peptidase (S15 family).	1.51339e-24
CP032698.1|AYG82246.1|4908041_4909250_+|Extracellular-serine-proteinase	gnl|CDD|173790	cd04077, Peptidases_S8_PCSK9_ProteinaseK_like, Peptidase S8 family domain in ProteinaseK-like proteins. The peptidase S8 or Subtilase clan of proteases have a Asp/His/Ser catalytic triad that is not homologous to trypsin. This CD contains several members of this clan including: PCSK9 (Proprotein convertase subtilisin/kexin type 9), Proteinase_K, Proteinase_T, and other subtilisin-like serine proteases. PCSK9 posttranslationally regulates hepatic low-density lipoprotein receptors (LDLRs) by binding to LDLRs on the cell surface, leading to their degradation. The binding site of PCSK9 has been localized to the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR. Characterized Proteinases K are secreted endopeptidases with a high degree of sequence conservation. Proteinases K are not substrate-specific and function in a wide variety of species in different pathways. It can hydrolyze keratin and other proteins with subtilisin-like specificity. The number of calcium-binding motifs found in these differ. Proteinase T is a novel proteinase from the fungus Tritirachium album Limber. The amino acid sequence of proteinase T as deduced from the nucleotide sequence is about 56% identical to that of proteinase K.	4.83245e-116
CP032698.1|AYG82253.1|4918673_4919504_+|Phthiodiolone/phenolphthiodiolone-dimycocerosates-ketoreductase	gnl|CDD|274680	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a domain found in a distinctive subset of bacterial luciferase homologs, found only in F420-biosynthesizing members of the Actinobacteria. [Unknown function, Enzymes of unknown specificity].	8.44971e-67
CP032698.1|AYG82248.1|4910293_4911127_+|3-alpha-(or-20-beta)-hydroxysteroid-dehydrogenase	gnl|CDD|187600	cd05341, 3beta-17beta-HSD_like_SDR_c, 3beta17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs. This subgroup includes members identified as 3beta17beta hydroxysteroid dehydrogenase, 20beta hydroxysteroid dehydrogenase, and R-alcohol dehydrogenase. These proteins exhibit the canonical active site tetrad and glycine rich NAD(P)-binding motif of the classical SDRs. 17beta-dehydrogenases are a group of isozymes that catalyze activation and inactivation of estrogen and androgens, and include members of the SDR family. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H)-binding pattern (typically, TGxxxGxG in classical SDRs and TGxxGxxG in extended SDRs), while substrate binding is in the C-terminal region. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr and Lys, as well as Asn (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	3.58911e-79
CP032698.1|AYG82249.1|4911271_4912399_+|Alkanal-monooxygenase-alpha-chain	gnl|CDD|225052	COG2141, COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion].	1.37096e-42
CP032698.1|AYG82247.1|4909356_4910301_+|Alkanesulfonate-monooxygenase	gnl|CDD|274680	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a domain found in a distinctive subset of bacterial luciferase homologs, found only in F420-biosynthesizing members of the Actinobacteria. [Unknown function, Enzymes of unknown specificity].	5.85843e-73
CP032698.1|AYG82255.1|4921474_4924114_+|FO-synthase	gnl|CDD|236422	PRK09234, fbiC, FO synthase; Reviewed.	0
CP032698.1|AYG82252.1|4916571_4918101_-|hypothetical-protein	gnl|CDD|213987	cd07432, PHP_HisPPase, Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase. HisPPase catalyzes the eighth step of histidine biosynthesis, in which L-histidinol phosphate undergoes dephosphorylation to produce histidinol. HisPPase can be classified into two types: the bifunctional HisPPase found in proteobacteria that belongs to the DDDD superfamily and the monofunctional Bacillus subtilis type that is a member of the PHP family. The PHP (also called histidinol phosphatase-2/HIS2) domain is associated with several types of DNA polymerases, such as PolIIIA and family X DNA polymerases, stand alone histidinol phosphate phosphatases (HisPPases), and a number of uncharacterized protein families. The PHP domain has four conserved sequence motifs and contains an invariant histidine that is involved in metal ion coordination. The PHP domain of HisPPase is structurally homologous to other members of the PHP family that have a distorted (beta/alpha)7 barrel fold with a trinuclear metal site on the C-terminal side of the barrel.	8.12386e-19
CP032698.1|AYG82257.1|4924759_4925380_+|hypothetical-protein	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.65877e-09

Protein sequences

>CP032698.1|AYG82252.1|4916571_4918101_-|hypothetical-protein
MTEHGPGPGPIGRRGLLATSAATALTLATVSFANAAPGSDPQRPDETRVVRGTLPPGSPDFVYLPVEVPHGVRELAVSYAYEKASVPAGTQNNALDIGIFDERGTALGGAGFRGWSGGARTAFFLRADDATPGYLRGPVRAGTWHIALGPYTVAPQGLPYTVTITLKYGGGTGPTPTPVYPPPRAKGRGRAWYRGDCHLHSVHSDGGRTPAEIAALARAAGLDFINTSEHNTTSGHRAWEGLWGDDLLIMTGEEITTRNGHVLALGTEPGHFIDWRYRARDNRFGHFAREVRAAGGLVVPAHPHATCVGCNWKFGFGDADAVEVWNGTYTPDDEVSLAEWDNSLALAARSGRPWLPAMGNSDAHRDPDRVGGPQTAVLADDLTKRAIQAGLRAGHSYVAESAALSLSFTVSGGHGQHAGIGERLRAAPDESVTARLEMTGAPPGCTAAFVTDQGTLYTTPLAASGTATATWETTPAYATYIRAEVRHAPTTPGLPGPLAAFTNPIFLTP
>CP032698.1|AYG82251.1|4914666_4916142_+|Betaine-aldehyde-dehydrogenase
MSDPQVGLAERKLFIAGEWVEPDGGHYPVLDPATEDVVGFAPEASREQVYRAAAAAREAFGAWSRTRPEERAAILDRAADLMQRDGAANTELARAETGATTATARGMQVAVGVARFRRYAKGALEPVEQALVPQINEAGPMGRAGVFGALAVRQPVGVVTCVTSYNNPWANPAGKVAPALAMGNTVVVKPAPQDPLSVFKMAEALEEAGVPRGVVNVVTGSAPAVGEAAVDAPDVDMVSFTGSTAVGQRIAEVCGRHMKRQLMELGGKGAAIVFDDADLGSAVGGIVTTFSFYSGQICTAPTRVLVQRGVHDQLVDKLAEYAGFLKVGDPAAPDTVLGPVISAAHRDRVESYVELGRKEGATVVTGGQRPPLERGFYVAPTLLAECTNDMRVAREEIFGPVVVVIPFDDEEEAIALANDSEYGLLDYVWSGDVARAFRVARRLRAGGVGVNTIGRNMEAPFGGFKRSGVGRDVGSYALHAYSELQSLVWPG
>CP032698.1|AYG82250.1|4912930_4914670_+|N-acyl-D-glutamate-deacylase
MLDHLIKGATLVDGTGAPPRTADVGIRGGRIALVEAPGTVTEAAASSEDASGLVLAPGFVDPHTHYDAQLFWDPYATPSMNHGVTTVAGGNCGFTLAPLHPDRPEDADYTRRMMSKVEGMSLKALEEGVSWGWSSFGDYLGALEGRIAVNAGFMVGHCALRRHVMGPDAVGGQPTPEQLDAMLALLHDAMDAGAWGLSTTQSSTHSDGDGRPVASRHALPAELLALSAAVGQHEGTQLEAIVAGCLDQFADDEIDLLVEMSAAAGRPLNWNVLTIDAAVPERVPRQLVPSERARKAGGRIVALTMPILTPMNMSLGTFCALNLIPGWGDILALPVPERIDRLRDAGVRAEMLRRADSKEAGIFRRLANFGRYVIGDTYSPENEGLSGRVVGDIAAERGLDPFHCLVEICANDRLRTVLWPMPTDNDPATWALRRETWEHEDVLLGGSDAGAHLDRMCGAPYTTRFLGDCLRGRRLVPLERAVKMLTDDPARLFGLRERGRIEEGFHADLVLFDPERIEAGPATLVHDLPGDSPRLDSKAIGIVSVRVNGVETLRDDRVTGAVPGTVLRSGRDTRTVSTK
>CP032698.1|AYG82249.1|4911271_4912399_+|Alkanal-monooxygenase-alpha-chain
MEFGLFVQGYVPAARSAVDPMAEHKALMEETKYVIQADKSGFKYAWASEHHFLEEYSHLSANEVFLGYLAHATERIHLGSGIFNPLAQVNHPVKVAEKVAMLDHLSEGRFEFGSGRGAGSHEILGFIPGVTDMNYTKEIWEETIAEFPKMWLQEEYPGFQGKHWSLPPRKIFPKPYGKSHPAMWYAAGSPPSYAMAARKGLGVLGFSVQKVSDMEWVLEQYKTAIQEAEPIGDFVNDNVMVTSTAICAPTHDEAVRIAVNGGLNRLQSLVFRYHDTFPRPEGIPEWPELLPEYSAEIIELLIAEELMICGDPGEVAAQCKRWEQAGADQLSFGLPIGVSFEDTLQTIRLIGEHVIPKIDTDPVHRTTRFRATTTP
>CP032698.1|AYG82248.1|4910293_4911127_+|3-alpha-(or-20-beta)-hydroxysteroid-dehydrogenase
MTEPLDGQDINHQEDRMGKLDGRVVFITGGARGQGEQEARLFVAEGARVVITDVLDEQGEALAKELGPEVARYLHLDVSREEEWTAAVTAAKDAFGSVDGLVNNAGILRFNALVDTPLDEFMRVVQVNQVGCFLGIKTVAPEIGAAGGGTIVNTASYTALTGMSAVGTYAATKHAILGLTRVAAMELAHLGIRVNAVCPGAIDTAMSNPAQLDPTADHAETSAALDDLYRKLVPLGRVGKPEEVAALALFLSSQDSSYITGQPFVIDGGWLAGVSLF
>CP032698.1|AYG82247.1|4909356_4910301_+|Alkanesulfonate-monooxygenase
MPILPNGRLVYGMQLPIQSQSTIYAEPWEADAGPGDLAEIARAAERSGFAYLASCDHVAIPRRLAGAMSTIWYDPVATLSFLAGVTDRILLMSHVAVAGLRHPLITAKQYATLDHLSGGRLILGVGAGHVREEFEAVGADFDGRGPALDETVDALRAALGPEEYPSFRGERFAFEGLGQRPRPAQRHVPIWVGGSSPAAVRRAALRGDGWLPQGDPRKALPAQIGRLKSLREQAGIVDPITVGAITEALYVGDPGWETGRRTLTGKPELLAESLRAYRAMGVDQIQVRFRSRDLGELLDQIAAFGADVAPHLHD
>CP032698.1|AYG82246.1|4908041_4909250_+|Extracellular-serine-proteinase
MSWVRSIAVGLTALGVVTAGLSSTAASGASAAPAGASRTATAGVTDAIPGSYLVTLKDAVVRADSAAGQAVARKYGATVRRTYHQAVNGYSIRASAQQAERLAGDPAVASVSANRAFHVTGTQPRPPSWGLDRIDQHKLPLDRSYTYPAGAGAGVTAYIIDSGVRISHQDFGGRASYGYDAVDDDQIAQDGYGHGTHVAAIAAGNRYGVAKKAKIVAVRVLDDAGSGTTEGIVAGIDWVTRHAAKPAVANLSLSGGADAVVDQAVRRSIASGVTYTVAAGNDNEDAAKHSPARVREAITVGSTTERDAREALSNYGAALDLFAPGESIASAWNASDTATVTDSGTSMAAPHVAGAAALYLAAHPKARPAQVAAALTAAATTGAVTRPGAGSPDRLLAIGARR
>CP032698.1|AYG82245.1|4907405_4907687_+|hypothetical-protein
MNDTKSPRATAPGAWTLPLLALAPLAVIGILGDRASSLWSSLSWVLWALSVVLVAAEWAWVFRQAARRPAHWGMCILVHAILAWQLIALLMKL
>CP032698.1|AYG82244.1|4906816_4907251_+|hypothetical-protein
MNRNSLRMAAVSAIAAVTLGGAAGLAQASEARVAAPQAVSVTQQAQQAEAQQAAHALLASPLAAQLTPAEQAEMKQIASGEFTAASKWSAIRAAFSKVGGFAKAIAGKYSDFKKWYDGLSWWVKAPLAAVSPGLTILDIYNALH
>CP032698.1|AYG82243.1|4905961_4906411_+|hypothetical-protein
MTFVLRPDTMSRMALTREDAEKILADNFAPWVLDLGLTVEETGARHAVLRLPWSDALARDGGGISGQALMAAADTATVIAVACARGAYGPMTTVQQSTTFQRPVTGADVLLDARVTKLGRRMAFADITMTADGADEPAAHASTVYALLG
>CP032698.1|AYG82253.1|4918673_4919504_+|Phthiodiolone/phenolphthiodiolone-dimycocerosates-ketoreductase
MRIAVTVFLTDQTITPVRLARELEARGFAGLYLPEHTHIPVERTTPYPAGGELPAEYGRTLDPFVALGQVSAVTEHLHLGTGITLVAQRDPIDLAKQIATLDHLSGGRFTLGLGFGWNKEEAADHGVEWGTRRELVRDRVALMRALWAAEPTAYEGEFGSVRASHAHPKPYRDGAPRILVGGAAGPKLFAHIAEYADGWLPIGGRGLSESLPVLRRVWEDAGRAASDLRVVPYAVLPAPGKLAHYAELGIEEVVLQLPSADETGVLKVLDEYAPYL
>CP032698.1|AYG82254.1|4919591_4921280_-|hypothetical-protein
MTSDGTRPNTAPSLYPELDEGALAGVVQALRTGDTSTLGPARAAEVAETRQVATFLDGVRVPAGEGVELDAALWLHNGDGPHPLIVMPSPWAKQGWLVYTIQAMRFARRGYHVLAYTARGFGESGGEVEVAGEKDIADGIAALDHLVSRAGGPEAVGRIGFLGDSYGSGISQLVAAEERRVDAVVALSTWGDLGEAFYENNTRHVAAVKTLLNAASTARLSERTQRAFDDVLANENVEETLVWAAERSPYHRVDKLNSRAVPVFFAQAWHETLFPGNQTLKTFNALSGPKRLLWSIGDHSGPEMTGILGLPNRVWEEAHSWFDQHLLETDGDEARAAAFDSESGARDQVVSEVMWGRALESRPTWHAATGTPERFYLTGPPEDGKDGGLLDKPTNGWHTTFTTGTDTPATVADQILLTGYAELAGLPKVYRTGRIDRAAAGVWTSAPLPSRHQLRGVPRLRVTLAPSEPDATFVAYLFDVDALGFARIITHAPYTVLGATPHTPAGADIALQVTGYDVRAGHRLMLVLDSVDPFYGDANTNPGTLTITSPDEEPSYLELPLS
>CP032698.1|AYG82255.1|4921474_4924114_+|FO-synthase
MTSSAQPPQAEGAGPVPQPGAAPTANSMRRALKRARDGVALDVAEAAVLLQARGDDLDDLTRSAARVRDAGLEAAGRPGVITYSKSVFIPLTRLCRDKCHYCTFVTVPGKLRRDSHGMFMSPDEVLDVARRGAELGCKEALITLGDKPEDRWPEAREWLDAHGYDDTIAYVRAMAIRILEETGLLPHLNPGVLSWTDFQRLKPVAPSMGMMLETTATRLWSEPGGPHHGSPDKEPAVRLRVLEDAGRSSVPFTSGLLIGIGETYEERADSLFALRRVARAYHGIQELIIQNFRAKPDTAMRGMPDAELDDLVATVAVARHIMGPAACLQAPPNLVAGEYGRLIGAGIDDWGGVSPVTIDHVNPERPWPRIEELVHKSAAEGFALRERLCIYPEFVRRGEPWLDPRLLPHVRALADPETGLAHEEAEVRGLPWQEPDEGFTATGRTDLHRTIDTEGRTGDRREDFDSVYGDWGALREAAAPGMVPSRLDADVRQALAVAADDPTKLTDAEALALLHADGEALDALCRIADDVRRSMVGDDVTYIVTRNINFTNVCYTGCRFCAFAQRRTDADAYTLSLSQVADRAEQAWEVGAVEVCMQGGIHPDMPGTAYFDIARAVKERVPGMHVHAFSPMEVVNGATRTGMSIREWLTEAKAAGLDSIPGTAAEILDDEVRWILTKGKLPTATWIEVVRTAHELGIRSSSTMMYGHVDQPRHWLGHFRTLARIQQNALANNVAGFTEFVTLPFIHTNAPVYLAGIARPGPTARDNRAVTAMARLLLHPHIPNIQTSWVKLGQEGAAEMLRSGANDLGGTLMEETISRMAGSSYGSYRSIKDLVAIAEAAGRPSRARTTLYGEVADERMAAAHASDGHLPELLPVVGD
>CP032698.1|AYG82256.1|4924110_4924638_-|hypothetical-protein
MSTTPEDRFVVLEPGETRPTRVPLPPGFGVKVTTTDSEGRLVVLENRLDVDVPLHVHELMDEFVYVLEGEMEIDYEGVTHRLTAGMCALLPHGVPHAMRNAFRPPVRTLQISTPGGWDRFLEDLFAAGPAVRTPDGAMDLAEVNALGEPYGMRYTPGTMALDRPEPPTTGRSRVS
>CP032698.1|AYG82257.1|4924759_4925380_+|hypothetical-protein
MWRMTGLRADARRNREKILAAARELFREQGTAVALDDIARRAEVGIGTLYRRFPDRDALITDVALEGFETGLAAVEGARAAGGGTVRVLDEMFRRVVAQRDRLVMPLIGGPVVRDPRVQELQRAILGALEEVLAEGRAEGVLRADVTAFDLVGAAAMACRPMPHLPPGAAAALAARHLAVYLHGLRPQGALALPAMVEVGEHLGLA
>CP032698.1|AYG82258.1|4925413_4927882_+|Beta-barrel-assembly-enhancing-protease
MQPSMQELIRRRKRAGFVGRRDELAVYRRNFDIPVDDERHRFVFRVYGNAGVGKTFLVRELEQAALERGALTAYTDESVDGVPETMAAISAGFARQGRTLKALDKILATYRQRRHEAEAGLGAGPGAGPSAGSVVAAQAGLAGMSLVPGVGPLVGTLDPVQLAQSAERLRATLSARLGRPEDVQLVLEPLRVLTPVFVEELGRVAAQVPWLAVFFDTYERTGAFLDDWLRDLVTTDRYGGLPANTVLTLSGQGRPDPLRWPAAADYAADLPLEPFTEDEARQLLATQGVLEEDVVRDVLRLSGRLPVLVSTLAGSRPATPDAIGDPSATAVERFLKWEPDPVRRSAALEGALPRRLDEDVFRAAVTGDAAGLFDWLRSLPFVRDQGGRIKYHDVVRAPMHRLQRTASPQRWRAGHERLAAWYARERAAAEGAAGRRWRDEAWREPRLEELYHRLCADPAGAFAEVLRDGIEACRQGTVTARRWARVIAEAGEDGNREALRKWGAVCLSALEAEQRHCVDVLGMMLARPELTDEDRVAVHIARAWGHFRSDAFDESLADYRRALTLDASSADAHHGRAVVHRAVGDHAAALADLARLEELEPGQARAPRERGETLRRAGRYEEAVAELGRALALDPGDALTLGSRGQAHAQLGDPARALEDFDRALLIDPDYGWALVRRAHVRGLVRDTVGALADLDRAEGLSPSWAWVLGERGDVYRFAGRYEEAVAAYGRALALDPGYAWALGSRAVALAELGRTTEALSDLDRAITLVPGYVWAYQQRARLHRLAGRDQEAQADLTRATEAATAQGIPRGPVPPEGVGSG
>CP032698.1|AYG82259.1|4928181_4930548_+|putative-type-I-restriction-enzymeP-M-protein
MDGRDFSDDRLLSRAELAALAGVMRPAVTNWQRRYEDYPEPVRAGESELFSLRAVLGWLDSRRIPSRARASDEPPGFTYADRMRRNIDASDRVRRSAALPNGEASSDALLGDEEQRARQLARLLGPMADVVRGGASMTDYVALLLSLVFLRMTGDPRSTSLPRTTRVRSKAATAALLQEIGEAADEALRLRGVAPGMQTAIVKLEPREYGDIVEVIRLTDGLGIEEFRQLVDEFGTRAGLPSGEFFTPRPVVRLMRDAAMDDESTVHQVYDPYVRAGEMLDGVAERLGGVVPLTLHGESPQRGTLMLAGMNLSLHTVPVELGAGTPAPWNERGWPKGHEADLILTNPPFNARGAVSRPREGIDWPYGAPPPGSPALAWLQHVLVSLKDEGRAAVVMPVSAGASTDVREREIRGRLVEDGVVECIVALPPQLFSGAQVSVSLWFLRRSTSVCEEILFVDARDLGDKAARGPRVLSDEHVEAVTDTVQTWRRSTGFRLGRQGAGHLAVAAPLDAVRAAGYSLSPADYVDRWMSTASPADAATEASTTRRTLDAARHRTKAVDEVADALSYGPLPSSVPLSYDGLPRNWCRVPLGELVDITAGPSYSRLSADVRSPTGDLCVVMPKHLREGRIDDRAMEKVAADVARALTKFRLSPGDILCVRSGAQTSPALVEEAQDGWLFSTNLLRLRTRETAGEPLVLPRYLHAYLCLPETVHWLKEYARGTAVPSLSAATLALLPVPLPPVAHQRRVSATLGALDAQIAAHRSLVGAATRHRSTLAAHLLTGVLVPE
>CP032698.1|AYG82260.1|4930592_4930805_+|hypothetical-protein
MSAPSSQPRSGTRYLWLLVAVLFSLVVALVAGILKAGTGVGFADAVLYGGTAFATSMGLCLLVLSAVGQL
>CP032698.1|AYG82261.1|4930947_4932072_+|hypothetical-protein
MSAAAGATAPVWGRAEQQDFRSRVRGCLLGGAIGDALGAGVAGLTLAQMRERHGTDALGDLVPAYGRPGAVSAATQLTLFTVDGLIRAQVRRDTGAWHPPTDVHRAHLRWAATQRDWGPDERREDNGWLAREEWLYARRDPAKACLVGLGDTVMGTLEHPKNPGADDPAALTRSAPFGLLVGWEPQLVLQLAVECATQTHGDPAAYLSAGALAVIVHGLARGESMDGAVQRAMAQLAVRPGHQPVTEALKHALGAVRQGMPSPALVATLGTGHSAPQALAIGVYCALVGEDIRHGLLLSVNHDGPSDATGTVCGSLLGAMHGETALPPAWLAQLEGRPTLLELADDFAMEMTQGPALHGPSVNTAGWLLRYPRG
>CP032698.1|AYG82262.1|4932154_4932625_+|hypothetical-protein
MTPPPTARTTHARRAPSARWFTAPLVALALLGTGAGPSAAAPADDAEHFQYVQSESEPAFTDPSARADELPPYDARDAQQAVDEMVMDEEEDAEGQHCPPTDDENRHENRNENRQGRYERWGPHRDAAYPADGIDGGGDGQDTAPVRDLDEPESLG

Crispr_ID: CP032698_58

• CRISPR_ID: CP032698_58
• CRISPR_location: 5049148-5049338
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP032698_58

Consensus_repeat	Method
AGGGGCGCGGGGAACTGCGCGA	PILER-CR
AGGGGCGCGGGGAACTGCGCGA	CRT

spacers of CP032698_58

>58.1|5049170|37|CP032698|PILER-CR,CRT
CCAGCCACGCACGGCCCGCAGTCGAAAACGGGTTTCC
>58.2|5049229|32|CP032698|PILER-CR,CRT
CCTGACCCGTCCGGGTCCGCACCGGTCCTGCC
>58.3|5049283|34|CP032698|CRT
GGTGCGGGCACGGTCCGCACACGAACGGGGGGTT

CRISPR arrays and Neighbor proteins around CP032698_58

CRISPR arrays

The CRISPR arrays of CP032698_58

>merge|CP032698|58|5049148-5049338|PILER-CR,CRT
AGGGGCGCGGGGAACTGCGCGACCAGCCACGCACGGCCCGCAGTCGAAAACGGGTTTCCAGGGGCGCGGGGAACTGCGCGACCTGACCCGTCCGGGTCCGCACCGGTCCTGCCAGGGGCGCGGGGAACTGCGCGAGGTGCGGGCACGGTCCGCACACGAACGGGGGGTTGGGGGCGCGGGGAACTGCGCAA

>CP032698|58|17|5049148-5049282|PILER-CR
AGGGGCGCGGGGAACTGCGCGA	CCAGCCACGCACGGCCCGCAGTCGAAAACGGGTTTCC
AGGGGCGCGGGGAACTGCGCGA	CCTGACCCGTCCGGGTCCGCACCGGTCCTGCC
AGGGGCGCGGGGAACTGCGCGA

>CP032698|58|7|5049148-5049338|CRT
AGGGGCGCGGGGAACTGCGCGA	CCAGCCACGCACGGCCCGCAGTCGAAAACGGGTTTCC
AGGGGCGCGGGGAACTGCGCGA	CCTGACCCGTCCGGGTCCGCACCGGTCCTGCC
AGGGGCGCGGGGAACTGCGCGA	GGTGCGGGCACGGTCCGCACACGAACGGGGGGTT
GGGGGCGCGGGGAACTGCGCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82361.1|5052755_5053724_+|UDP-glucose-4-epimerase	unknown	unknown	gnl|CDD|187558
CP032698.1|AYG82355.1|5043980_5045834_+|hypothetical-protein	unknown	unknown	gnl|CDD|370676
CP032698.1|AYG82365.1|5056746_5057244_-|Multiple-antibiotic-resistance-protein-MarR	unknown	unknown	gnl|CDD|197670
CP032698.1|AYG82356.1|5045880_5047764_+|hypothetical-protein	unknown	unknown	gnl|CDD|370676
CP032698.1|AYG82366.1|5057375_5058224_+|putative-trans-aconitate-2-methyltransferase	unknown	unknown	gnl|CDD|184509
CP032698.1|AYG82354.1|5041969_5043775_+|Energy-dependent-translational-throttle-protein-EttA	unknown	unknown	gnl|CDD|223562
CP032698.1|AYG82358.1|5049363_5049642_-|hypothetical-protein	unknown	unknown	gnl|CDD|129983
CP032698.1|AYG82350.1|5039233_5039827_-|hypothetical-protein	unknown	unknown	gnl|CDD|99749
CP032698.1|AYG82348.1|5036487_5037933_+|Anhydrotetracycline-monooxygenase	unknown	unknown	gnl|CDD|236199
CP032698.1|AYG82363.1|5055313_5055757_-|Acetyltransferase	unknown	unknown	gnl|CDD|223532
CP032698.1|AYG82351.1|5039940_5040180_-|hypothetical-protein	unknown	unknown	gnl|CDD|377231
CP032698.1|AYG82359.1|5049813_5051484_-|Sodium/glucose-cotransporter	unknown	unknown	gnl|CDD|271372
CP032698.1|AYG82353.1|5041159_5041813_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82360.1|5051703_5052759_+|Galactose-1-phosphate-uridylyltransferase	unknown	unknown	gnl|CDD|238341
CP032698.1|AYG82362.1|5053716_5054862_+|Galactokinase	unknown	unknown	gnl|CDD|223231
CP032698.1|AYG82357.1|5048156_5048843_+|putative-transcriptional-regulatory-protein-NarL	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG82364.1|5056041_5056788_+|Transcriptional-regulatory-protein-DegU	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG82352.1|5040176_5041028_-|hypothetical-protein	unknown	unknown	gnl|CDD|379262
CP032698.1|AYG82349.1|5038317_5039157_+|4-diphosphocytidyl-2-C-methyl-D-erythritol-kinase	unknown	unknown	gnl|CDD|235110
CP032698.1|AYG82367.1|5058325_5060086_-|hypothetical-protein	unknown	unknown	gnl|CDD|379232

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82361.1|5052755_5053724_+|UDP-glucose-4-epimerase	gnl|CDD|187558	cd05247, UDP_G4E_1_SDR_e, UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.08585e-169
CP032698.1|AYG82355.1|5043980_5045834_+|hypothetical-protein	gnl|CDD|370676	pfam09770, PAT1, Topoisomerase II-associated protein PAT1. Members of this family are necessary for accurate chromosome transmission during cell division.	1.0535e-12
CP032698.1|AYG82365.1|5056746_5057244_-|Multiple-antibiotic-resistance-protein-MarR	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	3.53482e-19
CP032698.1|AYG82356.1|5045880_5047764_+|hypothetical-protein	gnl|CDD|370676	pfam09770, PAT1, Topoisomerase II-associated protein PAT1. Members of this family are necessary for accurate chromosome transmission during cell division.	4.29956e-12
CP032698.1|AYG82366.1|5057375_5058224_+|putative-trans-aconitate-2-methyltransferase	gnl|CDD|184509	PRK14103, PRK14103, trans-aconitate 2-methyltransferase; Provisional.	8.95341e-120
CP032698.1|AYG82354.1|5041969_5043775_+|Energy-dependent-translational-throttle-protein-EttA	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	5.64637e-166
CP032698.1|AYG82358.1|5049363_5049642_-|hypothetical-protein	gnl|CDD|129983	TIGR00905, Arginine/ornithine_antiporter, transporter, basic amino acid/polyamine antiporter (APA) family. This family includes several families of antiporters that, rather commonly, are encoded next to decarboxylases that convert one of the antiporter substrates into the other. This arrangement allows a cycle that can remove proteins from the cytoplasm and thereby protect against acidic conditions. [Transport and binding proteins, Amino acids, peptides and amines].	0.0018736
CP032698.1|AYG82350.1|5039233_5039827_-|hypothetical-protein	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	2.65809e-20
CP032698.1|AYG82348.1|5036487_5037933_+|Anhydrotetracycline-monooxygenase	gnl|CDD|236199	PRK08244, PRK08244, monooxygenase.	2.22915e-115
CP032698.1|AYG82351.1|5039940_5040180_-|hypothetical-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.73734e-20
CP032698.1|AYG82359.1|5049813_5051484_-|Sodium/glucose-cotransporter	gnl|CDD|271372	cd11478, SLC5sbd_u2, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain. SLC5 (also called the sodium/glucose cotransporter family or solute sodium symporter family) is a family of proteins that co-transports Na+ with sugars, amino acids, inorganic ions or vitamins. Prokaryotic members of this family include Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. One member of the SLC5 family, human SGLT3, has been characterized as a glucose sensor and not a transporter. This subfamily belongs to the solute carrier 5 (SLC5) transporter family.	0
CP032698.1|AYG82363.1|5055313_5055757_-|Acetyltransferase	gnl|CDD|223532	COG0456, RimI, Acetyltransferases [General function prediction only].	1.49299e-07
CP032698.1|AYG82360.1|5051703_5052759_+|Galactose-1-phosphate-uridylyltransferase	gnl|CDD|238341	cd00608, GalT, Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme contains two identical subunits. It also demonstrates that the active site is formed by amino acid residues from both subunits of the dimer.	2.11416e-120
CP032698.1|AYG82362.1|5053716_5054862_+|Galactokinase	gnl|CDD|223231	COG0153, GalK, Galactokinase [Carbohydrate transport and metabolism].	3.00475e-118
CP032698.1|AYG82357.1|5048156_5048843_+|putative-transcriptional-regulatory-protein-NarL	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.59275e-32
CP032698.1|AYG82364.1|5056041_5056788_+|Transcriptional-regulatory-protein-DegU	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	4.05535e-39
CP032698.1|AYG82352.1|5040176_5041028_-|hypothetical-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	2.54644e-07
CP032698.1|AYG82349.1|5038317_5039157_+|4-diphosphocytidyl-2-C-methyl-D-erythritol-kinase	gnl|CDD|235110	PRK03188, PRK03188, 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional.	9.29011e-110
CP032698.1|AYG82367.1|5058325_5060086_-|hypothetical-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	1.45504e-06

Protein sequences

>CP032698.1|AYG82357.1|5048156_5048843_+|putative-transcriptional-regulatory-protein-NarL
MGVSSMGVRLMVVDDHRLLAEALASALKLRGHRVLAAAAPVAGAAELVVSRAPEVCLLGTASPAEPGVFDPIVRIKRERPQVAVVVLGPVPSPRGIAAAFASGASGYVRHDERIEGVERAMVKARAGEAAVAPGLLQGAFAELLNPAAQPDDEGQRLLRLLTPREVEVLVRVADGEDTRLIAAGMGIAPSTARTHVQRVLMKLGVGSRLEAAALAARTGLLDRATPPR
>CP032698.1|AYG82356.1|5045880_5047764_+|hypothetical-protein
MSQPPQPPQQPPRPEDTPPGFGAPQQPPAPGFGAPQQPPAGGFGAPTPPPPTGPPSTPPPAGPPAYGYPQTPPQQPGYGYPAAAPQQQPGYGYPQTPPQQPGYGYPGQPGQPGQPGYGYPGQPPTQPMQPQYPTPGAPGPGQPGGKKPNTQLTIIVAAVVAVALIVGGGIWYASGKDDGKSEANSGDTGGAKGSGGSATGGGGKEKAPANTAAHVLFQTPQPQVKDLTAVHGSWLTDKVYVKSGVKEIVGYDPAKGTQLWKLPLTGNVCESTTHVSADGKTAFAFESQDNGAKFASCTEVAGLDLTTGKLLWQADIKGANGDRKTRFDEVTLGAGTVAAGGLDGGAAWDLNTGKELWKPTTTADQCKDVGYGGGDALVAVRKCGDYEKPTINVQPLDPKTGQPLSTYKMVPGVQYAHIVSTKPLVLAADVGESAGDGSGISDFFSVDDKTGKLLARIPAPGDKYAADCDGTSVEKCTMVAAGGGKLFVPTEEHENASTANGSSGRTNEVVAFDLTTGQAVPGKADAGDGYKLHPLRMDGTNVIAYKDAPYDKGTQVVSIDGTTLKSTLLLENPSDRSVRGAITSFSTEFSEILYGNGRLYLGATLLSKPYSASDSDKKFLFMATGTS
>CP032698.1|AYG82355.1|5043980_5045834_+|hypothetical-protein
MTQPPSSQPPQGGFGAPQDKPQGPPAQPQGPPPQPPHMPPAPPAQPPQMPPAPPAGAPGYGYPQAPGQQPGYGYPQGPPPQPGYGYPGAPGQPPTQGNPYAQTQQGGYGYPGQPQYPGAPMPPQGGGGKNPFKGKPAMIVAAAVAGLLVIGGGVYLATSGGDDDKKPVADKSNSATPSGSPSVDKGDGKGDGRPGTGDDSGDVNAGIKPGEARVWYHENETPLTQNGATQYGPWRVGDVVVKAMYKEAVGYSVADGKEKWKVSLDTPICGAPHDTTADGKIVFGVQENNTKDAKCNQLQMIDFAAGKAGWKAPVPSENTFDIMVSFDMAISGNTVALARMGGASGFSIADGKKLYGTPKTGNCRSDAFAGGPKLISVGSCTDPNDNNLDSPPSELLQELDPATGKSKWNFQYEKGWTIRRVYSMDPLVVYATNKDKKTWNISTFTADGKLRSQVDSKAQLTASCSGFGIIDRQLQDCSGTAADANTLYISTEGKQSEELGVGRSNEVIAIDLATGKEKWHSAAPKGRMMSPLAVEGGKVVLYIEPGIDDAGAAVATLPPTGGAPQITLQSPAAASGTERNFYSPHTVWAGGRLFLLNGRVKSPKGDERDNSILSFGK
>CP032698.1|AYG82354.1|5041969_5043775_+|Energy-dependent-translational-throttle-protein-EttA
MAVNLVNVEAVSKVYGTRALLDGVSLGVSEGDRIGVVGRNGDGKTTLIRMLAQLEEPDTGRVTHVGGLRLGVLTQHDSLDPTATIRHEVIGDLADHEWAGNAKIRDVLTGLFGGLDLSGFAQGLDTVIAPLSGGERRRIALAKLLIGEPDLIVLDEPTNHLDVEGISWLAGHLQARRSALVCVTHDRWFLDQVCTRMWDVQRGSVFEYEGGYSDYVFARAERDRIAATEEAKRQNLMRKELAWLRRGAPARTSKPRYRIEAANELIADVPPPRDTSELMKFANARLGKTVFDLEDVTVQAGEKLLLKHLTWQLGPGDRIGLVGVNGAGKTSLLRALTEAWRTAGEAQPVAGKVAVGKTVRLAYLSQDVAELPPTLRVLEAVQQIRDRVDLGKGREMTAGQLCEQFGFAKEKQWTPVGDLSGGERRRLQLLRLLMDEPNVLFLDEPTNDLDIETLTQLEDLLDGWPGSMVVISHDRFFIERTTDHVWALLGDATLRMLPRGIDEYLERRQRMIAAAPAPAAVAAAKAAPAVSAQDARAAKKELQKVERQLNKINERETSLHAQIADNATDFGKVAKLDAELRELIVERDELEMRWLELAEDS
>CP032698.1|AYG82353.1|5041159_5041813_-|hypothetical-protein
MRRDVVRGAVVVVLAAAVLTGCGEEKNPGASAAPSRPVEPSSASGGGAAAAKAGGAVGSAGSACALPATFDLAAKWKPKAVAAEAGDSPLAGLTKQGPFALSCEIDAKPAGNIGFLRAWTDTATSGTPRAALESFVGADKTARKAAYAEIKAGSLPAAEVVYETYSKVMDTAKQERALAVVTPQGTLVLHLGGMDTEEHQEMLPAYELAKSSLKVTR
>CP032698.1|AYG82352.1|5040176_5041028_-|hypothetical-protein
MTESWERGGGGGCAGEPVSSDSLKTFGAFVQGLREHAGLTREEFATLVRFSKHTVESIELGRRMPDEEFVERAEAALGNTGALRRAFGHLTRQPGLAAWFREWARRERTAVSLCTYECRMVPGLLQSERYVRALYENEVPPLSDGQVETQIAARMERQRLLLERPNVPFSFIVTEAVFRQRIGGNAVTRDMLDHVLAATQPRNVTLQLLPADCEFHACLAGPLALLEGPDGKRYAYSEGQRNGRLISALKEVVPLQQRYDTLRSQALNPAKSRDLLERIRGAL
>CP032698.1|AYG82351.1|5039940_5040180_-|hypothetical-protein
MSTELAWFKSSYSSAQGDNCVEVALAWRKSSYSGTQGDDCVEVAVCPATVYVRDSKDKQGPHLALSSEAWTAFVAECRG
>CP032698.1|AYG82350.1|5039233_5039827_-|hypothetical-protein
MTAESVEHCHQWPVPPKDGYTVDDLFTLPNLPSHTELIDGSLIFVSPQRNFHTDVMEVLVSGLRRDLPSAFKIKREMTVVLDNRNGPEPDIIVVRAESVIGPDQTCYRAEDVLLAVEVVSPDSESRDRTTKPQKYAAAGIPNFWRVERGGNGSEPVVHVYELDPLTRAYVHVGMQRDQLKVTKPYATDIDLGAVREL
>CP032698.1|AYG82349.1|5038317_5039157_+|4-diphosphocytidyl-2-C-methyl-D-erythritol-kinase
MAPVSTPRIVTARVPAKVNVQLGVGPARPDGFHDLANVFLAVALYDTVTATPADTLRITCDGPDAAQVPLDRTNLAARAAELLAARHGIEPAVHLHIDKDIPVAGGMAGGSADGAGALLACDALWGTNATRAELLDICAELGSDVPFSLVGGAALGTGRGEKLAPLDVGGTFHWVFAVADGGLSTPAVYREFDRLTPDATAPRPHRRCSKHSVPAMRRPSRAPSPTTSRPPRSPCAPPSRTPSRRVRRRAPWPPWSRARARPRRSSAPTRRQPARSQPP
>CP032698.1|AYG82348.1|5036487_5037933_+|Anhydrotetracycline-monooxygenase
MDTDVLVVGAGPTGMTLANELLTAGVSTVVVDRLSRRSALSKAGGVQSRTLEMLDQRGLLEPLLATGDHPVATGHFAGVPLPHPSDRHRLPWRSVPQVVIEGFFEDHLAALGLHIRRDHELVGLAQDGTGVTATFADGTSLRSRYLVAADGGHSTVRSLLRAAFPGEPGTLTIIAADVRLDGADPSASHTWNEDGHWAAMFPLGTDVQGRPLRRLVLGGPGMSLPRETPVTEDDIRDGLKTVFGSRVQLLELCYARRITNASRQAEQYRHGRVFLAGDAAHVHLPLGAQGMNTGMQDAFNLGWKLGAAVRGWAPTGLLDTYHAERHPVGAAVLRNVRAQSLLMDWAGTRDPEVLAAREIFTDLAQLPDVQSHLANLMSGMAVRYPMPGAAASSDPLLGLPVPDLDLGGVRVHELLRAGRGVLLDPEDAYASVAAGFSGRVDRVGRGGATGPLLVRPDGYVCWAGSAWLGPALREWFGEPSV
>CP032698.1|AYG82358.1|5049363_5049642_-|hypothetical-protein
MSELHREVSELERKSASAARLFDIRRIIGGLFTLYGVIVGGAGVFVSDADLKKAQGVNINLWTGVGMLVLGLVFLTWLKLRPLAPPDAPEAP
>CP032698.1|AYG82359.1|5049813_5051484_-|Sodium/glucose-cotransporter
MQYLAAGLRLPTNGLDYTILAIYFIVVLGIGFAARASVKTSLDFFLSGRSLPAWVTGLAFVAANLGATEILGMSATSAQYGVAVVHWYWIGAIPAMVFLGLVMMPFYYGSKVRSVPEFLLQRFDKSAHLLASALFAFAAVLIAGVNLYALSIVVEALLGWPQWVAIVVAGLFVLAYITIGGLSSAIYNEVLQFFVILAALIPLTILGLKRVGGWDGLTGSLKAAHGDNFLSAWGGTGIGQANPLGANWLTIVLGLGFVLSFGYWTTNFAEVQRALSAKNLSAARRTPLIAAFPKMFIVFLVMIPGLVAAVLVPKIGTAGSDLTYNDAIPLLMQDLLPNGVLGIAVTGLLAAFMAGMAANVSSFNTVFTYDIWAKYVKKDRPDAYYLRFGRLITAIGVLASIGTAFIASSFSNIMGYLQTLFSFFNVPMFVVFVIGMFWKRASVKSGVWGLFAGTTAAMVNYFWIYKQGVVSIPTDQGANFVSAIVGFVAGAVVMVAVTLFTAPKPAAELAGLVYGTKSPGVEEPPAEGDSAWYRSPALLGWGAIALAALCYVPYSF
>CP032698.1|AYG82360.1|5051703_5052759_+|Galactose-1-phosphate-uridylyltransferase
MKKTSTRLADGRELLYYDARDDLVRDESDRRPLDPVSTASELRHDPLLGDTVVVASHRQGRTYLPPADACPLCPSRPDRDSEIPAADYDVVVFENRFPSLAGDSGRCEVVCFTPDHDASFADLTEEQAALVLEAWTDRTAELAELPQVQQVFCFENRGAEIGVTLGHPHGQIYGYPFTTPRTALMLRSLAEHRARTGGRNLFDDVVERELTERTRVVLEGEHWVAFVPYAAHWPYEVHLHPKRRVPDLRALDEGARTEFPQIYLELLRRFDRIFGPDEPPTPYISAWHQAPFRGEGAVDRAEFGLHLELFTIRRTSGKLKYLAGSESGMNVFINDVPPEAAAERLREVASK
>CP032698.1|AYG82361.1|5052755_5053724_+|UDP-glucose-4-epimerase
MSKYLVTGGAGYVGSVVAARLVEAGHTVTVVDDLSTGFREAVPAGAAFIEGRVQDAAKWLDATYDAVLHFAAYSQVGESVTVPEKYWANNVGGTMALLAAMRDAGVGRLVFSSTAATYGEPVSTPVTETDPTAPTSPYGASKLAVDHMIAGECAAHGLAAVSLRYFNVAGAHGSCGERHDPESHLIPLVLQVALGKRDFISVYGDDYPTPDGTCVRDYIHVADLAEAHLLALTAATAGEHLVCNLGNGNGFSVREVIETVRKVTGHEIPEVVTGRRAGDPAILVASAARAHERLGWRPARADLADIVADAWAFARRTERAGE
>CP032698.1|AYG82362.1|5053716_5054862_+|Galactokinase
MSEVASTFRELYGYEPDGVWAAPGRVNLIGEYTDFNEGFVMPLALPHTAVAAVSRRVDGVLRIHSADVAGPVVELRTDELTPRSGGGWAAYPAGVVWALREAGHPVTGADIHLASTVPTGAGLSSSAALEVVTALALRDLYELPLTRAELASLAQRAENAFVGVPCGIMDQTASACCTEGHVLHLDARDLTQRQIPFDLPAHGLRLLVVDTRVQHALGDGAYAERRAGCERGARELGVRTLRELPAARLPEALNELSDATVRGYVRHVVSDNARVTRVTELLAAGEVRAVGPVLTEGHASLRDDLRVSCAELDLVVDTAVGAGALGARMTGGGFGGSAIVLVEESARGVVSKALDSAFASASLAPPRLFEATPSTGAHRLS
>CP032698.1|AYG82363.1|5055313_5055757_-|Acetyltransferase
MFRLETEVDKGRQVRLQRRLRDSNAERSEVLRALRGTASSKEVPLHVWGLNEEGLLAGGLVGRTWAGWLHVDLLWIDPGVRSAGLGTQLLGRAEELARSERGCGYARVETWDFQAPGFYRGRGYEVVGVVPDYPPGVTEYTLTKRLP
>CP032698.1|AYG82364.1|5056041_5056788_+|Transcriptional-regulatory-protein-DegU
MVDDHRIFAESLAAALAAEPDVDVAAAGSGPAALRCLERGAAENRRFDVMLVDADLGASAAVPVARAVPEGGGAEGLVDGISLVAGVRSGQPAVRTVVLAEKDDPRRAALALQAGACGWVAKDCSLQRLLAVIRGVLREETHLPPALLTGVLRELTAARKHRTESERLVESLTPREREVLRCMVAGLGRKAVAERLFLSPHTVRTHMQNVLGKLGVHSTLAAVALARRAGVGPVDLAGDVVERGGQLA
>CP032698.1|AYG82365.1|5056746_5057244_-|Multiple-antibiotic-resistance-protein-MarR
MEDEVDRLVAAWRRERPDLDVEPLEVLSRVSRLARHLDRARRLAFAEHSLEPWEFDVLTSLRRAGAPYQLSPGQLLTQTLVTSGTMTNRIDRLAKKGLVERLPDPSDRRGVLVRLTPEGRDRADQALAGLLEQERAILGELSRNQRGELAALLRQLTAPFDNIPG
>CP032698.1|AYG82366.1|5057375_5058224_+|putative-trans-aconitate-2-methyltransferase
MHSDSSSTTPPGPPVWDPQQYLRHAGHRTRPFLDLLTRIPDLPTTGGLSPRIADLGCGPGNVTVRLADRWPDARITGFDLSPQMLAQADKDYAGTTAGGGWLDFQVADAAHWTPGEPFDLIVSNAALQWVPNHPESFPAWIDGLTPGGTLAFQVPGNFTSPSHAILADLCASPRWRGRLGDHGRRYVHILDTADYLTRLADLGCETDAWETVYCQLLTGPDPVLDWVKGTALRPVLTALDGDHEAIDALLAEYRDRLREAYPPGPHGTVFPFRRIFAVARKK
>CP032698.1|AYG82367.1|5058325_5060086_-|hypothetical-protein
MGGILSSVRTQRASRLAACTALVLSAGMLLAGPASADATPTGPHAVVKAPKSAESPSATLPHEAPAPTAQNKARRSAAVAVAGPHAPKPRFDVSGDGFSDLLVREPDDKLYLEDGSTQTNPELTGNLGAYKDLILPGDLGGGAAPEVLDLSPGGVLTLHADVTTGGIGYGSWSGTGWNMFNKVFSAGDVTGDGKNDLLARTPAGELYLYAGTGDLAAPFSAGHKFGTGWDMFDQVVGASDVNGDGLGDVYGRRPNGELYFYAGTGQAANPLNPGVKTGTGWDMYNQIIAVDDQNNDGLGDLVGRDLTGKLWFYPSQADGHQGARSALGTGWRSAQFFTAGGNVTYGKNDLFGIDGAGTLSSYWGLGDGYLSAPVRGTKGGWAGAHYVSNPSSLVTSERWASILEVTSNGDLVVNGNRIGSGWGIYNTVIGVGDLTGEGNGDLITRQGGNGHLYLYPGNGQGTGVYSRIDVGGGWNIYDKLFGAGDVNGDGLPDLLARTPGGELYLYAGTGNAKVPFKGRVKIGTGWNMYGASKIAVSGDLTGDGRSDIVAVDSAGDLWRYDANGSGGFKGRVKIGYGWNLYQYGIY

Crispr_ID: CP032698_59

• CRISPR_ID: CP032698_59
• CRISPR_location: 5075193-5075387
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP032698_59

Consensus_repeat	Method
TTAGGGGCGCGGGGAACTGCGCGA	CRISPRCasFinder

spacers of CP032698_59

>59.1|5075217|32|CP032698|CRISPRCasFinder
GAAGCGACCACGACCCGCAGGATCGAGAGGGT
>59.2|5075273|35|CP032698|CRISPRCasFinder
CCAGCCACGCACGGTCCGCAGCCGAAAACGGGTTT
>59.3|5075332|32|CP032698|CRISPRCasFinder
GAAGCGGGCACGGTCCGCACATGACCGGGGGT

CRISPR arrays and Neighbor proteins around CP032698_59

CRISPR arrays

The CRISPR arrays of CP032698_59

>merge|CP032698|59|5075193-5075387|CRISPRCasFinder
TTAGGGGCGCGGGGAACTGCGCGAGAAGCGACCACGACCCGCAGGATCGAGAGGGTTTAGGGGCGCGGGGAACTGCGCGACCAGCCACGCACGGTCCGCAGCCGAAAACGGGTTTTCAGGGGCGCGGGGAACTGCGCGAGAAGCGGGCACGGTCCGCACATGACCGGGGGTTTTGGGGGGCGGGGAACTGCGCGA

>CP032698|59|43|5075193-5075387|CRISPRCasFinder
TTAGGGGCGCGGGGAACTGCGCGA	GAAGCGACCACGACCCGCAGGATCGAGAGGGT
TTAGGGGCGCGGGGAACTGCGCGA	CCAGCCACGCACGGTCCGCAGCCGAAAACGGGTTT
TCAGGGGCGCGGGGAACTGCGCGA	GAAGCGGGCACGGTCCGCACATGACCGGGGGT
TTTGGGGGGCGGGGAACTGCGCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82374.1|5067780_5068731_+|HTH-type-transcriptional-regulator-BenM	unknown	unknown	gnl|CDD|176106
CP032698.1|AYG82381.1|5076132_5076654_-|hypothetical-protein	unknown	unknown	gnl|CDD|373065
CP032698.1|AYG82371.1|5065411_5065879_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82378.1|5072747_5073608_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82377.1|5071070_5072519_-|Bifunctional-protein-GlmU	unknown	unknown	gnl|CDD|184641
CP032698.1|AYG82376.1|5069978_5070953_-|Ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl|CDD|179535
CP032698.1|AYG82379.1|5073677_5075081_+|Sensor-histidine-kinase-LiaS	unknown	unknown	gnl|CDD|226951
CP032698.1|AYG82375.1|5068727_5069615_+|Beta-lactamase-regulatory-protein-BlaB	unknown	unknown	gnl|CDD|379138
CP032698.1|AYG82372.1|5065990_5066584_-|Peptidyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|235457
CP032698.1|AYG82385.1|5082545_5084117_-|Multidrug-resistance-protein-3	unknown	unknown	gnl|CDD|341045
CP032698.1|AYG82389.1|5089452_5089962_-|hypothetical-protein	unknown	unknown	gnl|CDD|371045
CP032698.1|AYG82384.1|5081038_5081932_+|hypothetical-protein	unknown	unknown	gnl|CDD|274008
CP032698.1|AYG82386.1|5084378_5085167_+|Bacitracin-export-ATP-binding-protein-BceA	unknown	unknown	gnl|CDD|213222
CP032698.1|AYG82388.1|5087980_5089435_-|hypothetical-protein	unknown	unknown	gnl|CDD|370724
CP032698.1|AYG82373.1|5066732_5067320_-|50S-ribosomal-protein-L25	unknown	unknown	gnl|CDD|235534
CP032698.1|AYG82370.1|5062293_5065023_+|Phosphoenolpyruvate-carboxylase	unknown	unknown	gnl|CDD|366019
CP032698.1|AYG82387.1|5085163_5087740_+|ABC-transporter-permease-YtrF	unknown	unknown	gnl|CDD|223650
CP032698.1|AYG82382.1|5076961_5077948_+|hypothetical-protein	unknown	unknown	gnl|CDD|379604
CP032698.1|AYG82383.1|5077956_5080788_+|IgA-FC-receptor	unknown	unknown	gnl|CDD|373070
CP032698.1|AYG82380.1|5075415_5075904_-|hypothetical-protein	unknown	unknown	gnl|CDD|379608

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82374.1|5067780_5068731_+|HTH-type-transcriptional-regulator-BenM	gnl|CDD|176106	cd08414, PBP2_LTTR_aromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LTTRs involved in degradation of aromatic compounds, such as CbnR, BenM, CatM, ClcR and TfdR, as well as that of other transcriptional regulators clustered together in phylogenetic trees, including XapR, HcaR, MprR, IlvR, BudR, AlsR, LysR, and OccR. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the substrate-binding domains from ionotropic glutamate receptors, LysR-like transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	7.20901e-35
CP032698.1|AYG82379.1|5073677_5075081_+|Sensor-histidine-kinase-LiaS	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	8.84173e-37
CP032698.1|AYG82370.1|5062293_5065023_+|Phosphoenolpyruvate-carboxylase	gnl|CDD|366019	pfam00311, PEPcase, Phosphoenolpyruvate carboxylase.	0
CP032698.1|AYG82387.1|5085163_5087740_+|ABC-transporter-permease-YtrF	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	1.02216e-26
CP032698.1|AYG82377.1|5071070_5072519_-|Bifunctional-protein-GlmU	gnl|CDD|184641	PRK14352, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
CP032698.1|AYG82376.1|5069978_5070953_-|Ribose-phosphate-pyrophosphokinase	gnl|CDD|179535	PRK03092, PRK03092, ribose-phosphate diphosphokinase.	0
CP032698.1|AYG82381.1|5076132_5076654_-|hypothetical-protein	gnl|CDD|373065	pfam14431, YwqJ-deaminase, YwqJ-like deaminase. A member of the nucleic acid/nucleotide deaminase superfamily prototyped by Bacillus YwqJ. Members of this family are present in a wide phyletic range of bacteria and a few basidiomycetes. Bacterial versions are predicted to function as toxins in bacterial polymorphic toxin systems.	2.00206e-15
CP032698.1|AYG82375.1|5068727_5069615_+|Beta-lactamase-regulatory-protein-BlaB	gnl|CDD|379138	pfam13354, Beta-lactamase2, Beta-lactamase enzyme family. This family is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	6.35947e-46
CP032698.1|AYG82372.1|5065990_5066584_-|Peptidyl-tRNA-hydrolase	gnl|CDD|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	3.37845e-94
CP032698.1|AYG82389.1|5089452_5089962_-|hypothetical-protein	gnl|CDD|371045	pfam10428, SOG2, RAM signalling pathway protein. SOG2 proteins in Saccharomyces cerevisiae are involved in cell separation and cytokinesis.	0.000827307
CP032698.1|AYG82384.1|5081038_5081932_+|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00477051
CP032698.1|AYG82386.1|5084378_5085167_+|Bacitracin-export-ATP-binding-protein-BceA	gnl|CDD|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	4.43296e-110
CP032698.1|AYG82388.1|5087980_5089435_-|hypothetical-protein	gnl|CDD|370724	pfam09852, DUF2079, Predicted membrane protein (DUF2079). This domain, found in various hypothetical prokaryotic proteins, has no known function.	4.5816e-50
CP032698.1|AYG82373.1|5066732_5067320_-|50S-ribosomal-protein-L25	gnl|CDD|235534	PRK05618, PRK05618, 50S ribosomal protein L25/general stress protein Ctc; Reviewed.	4.84643e-63
CP032698.1|AYG82383.1|5077956_5080788_+|IgA-FC-receptor	gnl|CDD|373070	pfam14440, XOO_2897-deam, Xanthomonas XOO_2897-like deaminase. A member of the nucleic acid/nucleotide deaminase superfamily prototyped by Xanthomonas XOO_2897. Members of this family are present in a wide phyletic range of bacteria and are predicted to function as toxins in bacterial polymorphic toxin systems. The Xanthomonas XOO_2897 lack an immunity protein and is predicted to be deployed against its eukaryotic host.	2.42241e-32
CP032698.1|AYG82382.1|5076961_5077948_+|hypothetical-protein	gnl|CDD|379604	pfam14414, WHH, A nuclease of the HNH/ENDO VII superfamily with conserved WHH. WHH is a predicted nuclease of the HNH/ENDO VII superfamily of the treble clef fold. The name is derived from the conserved motif WHH. It is found in bacterial polymorphic toxin systems and functions as a toxin module. WHH is the shortest version of HNH nuclease families. Like AHH and LHH, the WHH nuclease contains 4 conserved histidines of which the first one is predicted to bind a metal-ion and other three ones are involved in activation of water molecule for hydrolysis.	1.41348e-11
CP032698.1|AYG82385.1|5082545_5084117_-|Multidrug-resistance-protein-3	gnl|CDD|341045	cd17502, MFS_Azr1_MDR_like, Saccharomyces cerevisiae Azole resistance protein 1 (Azr1p), and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including various Saccharomyces cerevisiae proteins such as azole resistance protein 1 (Azr1p), vacuolar basic amino acid transporter 1 (Vba1p), vacuolar basic amino acid transporter 5 (Vba5p), and Sge1p (also known as Nor1p, 10-N-nonyl acridine orange resistance protein, and crystal violet resistance protein). MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.09648e-58
CP032698.1|AYG82380.1|5075415_5075904_-|hypothetical-protein	gnl|CDD|379608	pfam14433, SUKH-3, SUKH-3 immunity protein. This family belongs to the SUKH superfamily and functions as immunity proteins in bacterial toxin systems.	4.15293e-62

Protein sequences

>CP032698.1|AYG82379.1|5073677_5075081_+|Sensor-histidine-kinase-LiaS
MPDYGVFDDFSCGARRAKAQGKSFALARTLGAMTVTGADQEATGLTSRGWWWWERRRSAVLDVSLGVFSALECALEGVNFAGDAGIAVPAGVVLGLVAGASLVLRRRWPIAVVLVSIAVTPASMGFLLSVVGLYTLAASDVPRRITAALAGMSVAGTFIVTFVRMHQSVARGDYDPGLWYVPLVSVVMSLGITGPPLLYGLYIGARRRLMESLRERADSLERELSLLADRAEERAEWARTEERTRIAREMHDVVAHRVSLMVVHAAALQAVARKDPEKAVRNAALVGDMGRQALTELREMLGVLRADQQSVAVRLDPVPLAAVGAAAAAAAAAVEEGPCLADIEALVGQSREAGMVVELLVQGEARGCDALVEQTAYRVVQEALTNVHKHAAGAKVRVRLAYRAAEVAMQVENGPADGVTADAGLPSGGNGLVGMRERVLALGGVFVSGVTEEGGFRVSAVLPDASE
>CP032698.1|AYG82378.1|5072747_5073608_-|hypothetical-protein
MTSTTPGKYADFEGLRRQAIALRREGLSLRQIRDRLHVDNNDLLHRLVKGEPAPEWTKRPNAKDDLRDRARELRTQGMTYDQIQVELGCSKSSISLWVRDLPKPEPRYTDEERRARMNAGLSRLRAAQDEERQATKRAARDEIGRLSDREVFIAGVALYWAEGAKDKTYRRSEQLQFINSDPNVIKLYLRWLELLGVSRDRMHFRVSIHESGDVAGAEKFWAELASVDVSVFQRATLKKHNPRTKRKNTTEAYRGCLVIYVTKSADLYRRMEGAWYGIVLGADPAT
>CP032698.1|AYG82377.1|5071070_5072519_-|Bifunctional-protein-GlmU
MSATRPAAVVVLAAGEGTRMKSATPKVLHEICGRSLVGHVVAAARELDPEHLVVVVGHAREQVSAHLGAIDAEVRTAVQYEQNGTGHAVRMALEELGQSIEGTVVVVCGDTPLLTGATLAELTRTHESDRNAVTVLTAEIADSTGYGRIVRDDVSGAVTAIVEHKDATDAQRAIREINSGVFAFDGALLADALGKVRTDNSQGEEYLTDVLGILREAGHRVGASLAGDFREILGINNRVQLAEARRLLNDRLLERAMLAGVTVVDPATTFVDVQVTFEQDAVVLPGTQLLGATHVASGAEVGPNARLTNTVVGRGARVDNTVSYDSQVGEGATVGPYAYLRPGTRLGVKAKVGTYVETKNATIGDGSKVPHLSYVGDATIGEFSNIGAASVFVNYDGEAKHHTTIGSHCRTGSDNMFVAPVTVGDGAYTAAGSVITKDVPPGSLAVARGQQRNIEGWVERKRPGSAAAQAAQAAAERPAGEN
>CP032698.1|AYG82376.1|5069978_5070953_-|Ribose-phosphate-pyrophosphokinase
MTGIKTTGEKKLMLFSGRAHPELAEEVAHQLGVGLVPTKAFDFANGEIYVRFQESARGADCFLIQSHTAPINKWIMEQLIMIDALKRASARSITVIIPSYGYARQDKKHKGREPISARLVADLLKTAGADRILTVDLHTDQIQGFFDGPVDHLTALPVLADYVGAKVDRSKLTIVSPDAGRVRVADRWCDRLDAPLAIVHKRRDKDVANTVTVHEVVGDVKGRVCVLVDDMIDTGGTICAAADALFAHGAEDVIVTATHGILSGPAADRLKNSKVSEFVFTNTLPDPSDLELDKITVLSIAPSIARAVREVFEDGSVTSLFEEN
>CP032698.1|AYG82375.1|5068727_5069615_+|Beta-lactamase-regulatory-protein-BlaB
MNSPVRSRITAAFTDAGLSGALCATDIDHGTTVTLAADTPVSTASVHKLCLVATLYREAAAGRLDPTTPVDIPAAARAPGPTGLAVMRDAARLSLRDLASLAIAVSDNAAADILWDHLGLDTVNATMAALGLPRTIAVHNQAGLYATMVDDTGSGGPAALVDPAAVARLTVLDPHRTNRSTPREITALLTAIWRDDLCPPPWAEELRAVLGVQAWSHRLASGFPFDDVRVSGKTGTLPTQRHEAGVVEYPDGGRYAVAVFTRAASTAVTLPAADAAIGRAARIAVDALRARRGGP
>CP032698.1|AYG82374.1|5067780_5068731_+|HTH-type-transcriptional-regulator-BenM
MDLLLHLRYFRAVAEEQHFGRAAERLRVAQPSLSQRIQRLERELGVRLLDRGRAGATLTPAGRLVLAETDALLDAADRLRTLVTRVQGGAAGTLRAAVPPQLGGATIAALLTAYRERSPGGHLDLRELTTADLTAELAAGTLDAGIVRHPCPATGLGFGPQLHQPLGALLADHDPLAQHTEVDVPDLDGRELVLFPRPTAPALHDETLTACARHGCTPSAVREVAGLEFTRALLLSGTDVVALLPRPTPEPGTTWRLLRGNPLTWRTSTAWPAGRDGPAVRLFTEAAHDVLREHAGLLPTATPRRLFPRPASEFPL
>CP032698.1|AYG82373.1|5066732_5067320_-|50S-ribosomal-protein-L25
MSEVKLAAEVRTSFGKGAARSIRRENKVPGVIYGHGTEPVHVTLPGHDLLLALRTANVLLSLDIDGKTELAIPKAVQRDAIKGYLVHVDLLLVKKGEKVTVEVAVETEGDLAPGSFLVENVLNTLSVETEATHIPTSVTVSIEGLEAGAAIHAKDIELPAGTTLATDPEAVVIQILSAQAEEPAADAEAGEGAEA
>CP032698.1|AYG82372.1|5065990_5066584_-|Peptidyl-tRNA-hydrolase
MTTDANAPWLIVGLGNPGPEYTANRHNVGFMVADLLAERIGGRFKAHKARAQVVEGRIGPPGPLNRRVVLAKPMSYMNLSGGPVTALRDFYKVPLANIVAIHDELDIDYGVLRLKLGGGDNGHNGLKSITKSLGADYHRVRFGIGRPPGRMQVADFVLKDFSSTERKELGYFVDRAADAVEALVIEGLERAQSTYNS
>CP032698.1|AYG82371.1|5065411_5065879_-|hypothetical-protein
MTKRSRTFLLFGLRAASALVAALLVVAGFWSSWGTAQHVVLAKGRDHGTLTVTGCADDVCTGGYVPRPGSAPHAHVTIAESVAARRGDHLPVVLKPGTDEAVRSGVAGFLYAWLPLAGALLLASLVVAGGLRMPRTAWVAGVLGATAMASAFIAL
>CP032698.1|AYG82370.1|5062293_5065023_+|Phosphoenolpyruvate-carboxylase
MSSADQTPAASNELRADIRRLGDLLGETLVRQEGPELLELVERVRALTRSDGEAAADLLGGTEVETAAKLVRAFSTYFHLANVAEQVHRGRELRAHRAAEGSLLARTADMLKDGDPEHVRESVKNLNVRPVFTAHPTEAARRSVLNKLRRIAELLETPVIDSDRRRHDLRLAENIDLIWQTDELRVVRPEPADEARNAIYYLDELHAGAVGDVLEDLAAELERVGVELPPGTRPLTFGTWIGGDRDGNPNVTPKVTWDVLILQHEHGINDALETIDFLRGLLSNSIRYAGATQELLDSLQADLEALPEISPRYKRLNAEEPYRLKATAIRQKLVHTKDRLANGTAHQPGRDYLGTADLIADLTLIQTSLRAHRGALFADGRMDRTIRTLAAFGLQLATMDVREHADAHHHALGQLFDRLGEESWRYADMPRDYRQKLLAKELRSRRPLAPTPAPLDAAGEKTLGVFGTIKEAFERFGPEVIESYIISMCQGADDVFAAAVLAREAGLVDLHAGWAKIGIVPLLETTDELRAADVILDEMLADPSYRRLVSLRGDVQEVMLGYSDSSKFGGITTSQWEIHRAQRRLRDVAHRYGVRLRLFHGRGGTVGRGGGPSHDAILAQPWGTLEGEIKVTEQGEVISDKYLIPSLARENLELTVAATLQASALHTAPRQSDEALARWDAAMDTVSDAAHSAYRRLVEDPDLPAYFFASTPVDQLAELHLGSRPSRRPDSGAGLDGLRAIPWVFGWTQSRQIVPGWFGVGSGLKALREAGLDAVLDEMSEQWHFFRNFLSNVEMTLAKTDLRIARHYVDTLVPDELKHVFATIEAEHELTVREVLRITGRDELLGASPVLQQTFAIRDAYLDPISYLQVALLARQRAAADRGEAPDPLLSRALLLTVNGVAAGLRNTG
>CP032698.1|AYG82380.1|5075415_5075904_-|hypothetical-protein
MPDVSTTRFPVPVDAALRTAGWQPGRWDIRQAEAWADVLRAHTSPAGHRHTVFPAAVEAWAEFGGLHLTSPGPGRRNAPATLRFDPLAGLHLARTLADLGRALDTDIAPLGEEGDQQAVLAIDTGGRVYSLDHTGDWYLGPDIDHALTTLITGTQPIRLTPA
>CP032698.1|AYG82381.1|5076132_5076654_-|hypothetical-protein
MHAASVTSAGNTVAAMTEAPGDPRLRWSATTAGPAPLLRHRRDGILPAIAAALSVRGETLTCTAGKGEQPPVLHTLVQDYLDTLTSGQRERFTGRCPEAILLSRHLTAVEAGRSKRAQRKPLTHGEARRSLKHAKLTARRIREDGDPLHGSYAPPCRSCTALLDHFGVRTIEL
>CP032698.1|AYG82382.1|5076961_5077948_+|hypothetical-protein
MTTGRLGQQAAPPNAAYAGQVVHFPDPVRAARHPRGVRMDENGFPDFSAYARAAAEIAEPPEGFGVDELRLTDYVSANAALSAAGHALWDTVAPVATPHGWTWHHVPGGRRLELVPVEVKALLRHYGGLATAPVEHDKRGTRPLQETWPAHFGLPKGAVSVTESQLLGVEEDLGYRLPGAYRSFLKAAGGCAPVGAALDAELGLLVDQPFFTVRDEAAVNDLVYINKCLRDHLTKDYLGVAFVQGGILAVKVKGSAVGSVWFCAYDDARDQDGLSVHERVERLLLPCGDDFDAFLARLAGNPPELETVANLMVDGGFARAVETTSVGE
>CP032698.1|AYG82383.1|5077956_5080788_+|IgA-FC-receptor
MVTFAQAQERAEEWINGDVPAYQHREVRVREFELGFVVWAEDRENGPSGGGGAQRLVIARDSGEASLWPGLPVGEVIRRYEEEYGVPEDAPVAPEPPARIDLNQTSFLLSPPEWLQEAADRLGIPDRRDEGGRAAGAAGAVAGAGGAGSAGAGVGTGAGAPQGASGAGRAGAGGSGSGAGESVGEPAAPAWPAPAAASSAPGPGPGPVSGGGTPAGGTPWAGTDTNAGSDDGSVPLPATVFAPALSGSDGEDDEPPRVTPEAKTALMAGGSQLPPTALATPAYDPQGGPPPGAHPATASPQGAPSAPASRSAGPVEPAGPGDIADAATSKAAGPPPGARPSRGGGATTPPPPGAPGTPGARPGVPAAAPSPGSTPPPGAPAGGYLPTQLVSQLGAQGPQPPGPPTPPPAQGGVHQAATMFADPSRLGAPGQSGPGAPMPPGPPGAPHAPMPPGAPGAPGAPQPPGPPGAPGTPPGGVHHAATMLAGPAQMGPGGPGAPMPPGPPGVPGTPGGPGAPMPPGPPGPPGGPQPPGAPGAPGAPGAPGGGVHQAATMLAGPAQMGPGGPGGPGAPMPPGPPGPPGVPQGAPVPQAPPGVPQAPPGVPQAPSAYGYPQQPPTGLPTVGPGYQAVLRYRAPDGSEQQLIRRSAPGTPHPEWQIFHELRAMNVPADHVLELHTELESCELPGGYCARMIREQWPQVRITHVAPYGKDHGSRRQGVQHLLTHQGELAQVADGPARPQPVRAPLVPVQPLPPLPPEGVAHELAGAFGPQGTFRFDQRAVSRQGVPEVVAVTLVWAGLPVDFGPFFWAQAVPGQPVPTLAELAQQRGVQPAADAGSYLVMGSDFGRAICVQYGTANIVAVPVEAGPGGQSVPPQFVNSGLPEFVRSLALLGRMWRLRFGLNPEQAGRWTVDFQAQLAALDPAALASPESWWSVLLEQMWDGLL
>CP032698.1|AYG82384.1|5081038_5081932_+|hypothetical-protein
MSAASTPPAQPFGFGRGRGYRPDQVDRTLARISGERDAAWERAARLTVLAKQMSAQAAALNEQVAGLAPQTYDVLGERAAAMFALTVEEADAVRAGAEEDAAGQVRAGEEAGRALRDAARSHSEALLAATEAWVQRTLLAARTEADALRDAARAEAKEWREEAAGELDGMRRRCETYLAGQEQERAEAFAADERERAAREAELEARLAELTAAAQSALDQARRGFAEAEEEARRIQEDAQTRAAELVAGARAQEDRIGAETERVLREHVGVREEVQAHMAHVRNSLATLTGRSPEES
>CP032698.1|AYG82385.1|5082545_5084117_-|Multidrug-resistance-protein-3
MSVFDEAPGTDAAIPGATPDAVPARGRGPVVAALMMGMALVALDGTIVSTAVPQIVGDLGGFAVFSWLFSGYLLAVTVTLPVYGKLSDTFGRKPVLIAGVILFLTGSVLCAFAWNMAALIAFRIVQGLGGGALQGTIQTIAADLYPLKERPRIQARLSTVWAVSAVAGPALGGLLAGYADWRWIFLINVPVGIITLYLVARHLTEPARTAPAARPRVDWAGALCVFATGALLLTALVQGGVAWPWLSPPSLALFAGSAGCAALTAYVERRAAEPVIPGWVWRRRTIAAVNLAFGGLGLLMVAPTVFLPTYAQSVLGLNPTAAGFVLSVMTLSWPLSAALSSRVYTRLGFRDTAVIGITLALLILLAFPLLPFPGRAWQPALLMLLLGGALGLFQLPLIVGVQSTVGWAERGTTTASVLFCRQIGQSVGAALFGAVANATLASRLAHAPAPGPAGDLDSVARALRHPADLSAEAADLLRRAVASAVGHVYLGAAIAAALSLLVLLLLAPRHFPVLPQPTPGEDV
>CP032698.1|AYG82386.1|5084378_5085167_+|Bacitracin-export-ATP-binding-protein-BceA
MTTAVTIPRHGGTGGGTAVAARARQVVKAYGSGETRVVALDRVDVDMARGQFTAIMGPSGSGKSTLMHCLAGLDTVTSGQIHLDDTEITGLKDKRLTQLRRDRIGFIFQAFNLLPTLNALENITLPMDIAGRRPDEKWLERVVETVGLAGRLKHRPTQLSGGQQQRVAVARALASRPEIIFGDEPTGNLDSRAGAEVLGFLRRSVDELGQTIVMVTHDPVAASYADRVVFLADGRIVDEMFHPTADAVLDRMKDFDARGRTS
>CP032698.1|AYG82387.1|5085163_5087740_+|ABC-transporter-permease-YtrF
MSVLKTSMRNFLAHKGRMALSAVAVLLSVAFVCGTLVFTDTMNTTFDKLFAATASDVTVSPRSATDDGAPSATGKPEALPAALVERIAKVPGVRGAEGAVGSTSVTVVNAKNENMGSTTGAPTIAGNWTDNDLKAMEITSGRAPRGPTEMMVDADTADKHHLAIGDELRTIAVTGDFTAKITGIATFKVTNPGAAVVYFDTATAQKQLLGATGQFTQINVTAANGVSDARLKQDVAAALGSGPYKLQTAQEAKDAGRDSVGSFLDVMKYAMLGFAGIAFLVGIFLIINTFSMLVAQRTREIGLMRAIGSSRKQVNRSVLVEALLLGVFGSVLGVGAGIGIAVVLMKLMGAIGMDLSTDDLTVRWTTPVVGLALGVVVTIVAAYVPARRAGKISPMAALRDAGTPADGRAGAVRATIGLLLTALGTAALFGAANSSQASAGSALLGLGVVLTLIGFVVIGPLLAGVVVRAISAVVLRMFGPVGRMAERNALRNPRRTGATGAALMIGLALVACLSVVGASMVASATDELDRSVGADFIVSSNAQQPIVPQAADAVRKAPGLAHVTNYTSLDVRLTTPDGKSVNDRIAVTDPTYQQDVRRKTVAGDLAAAYGKGAMSVGDTYAKEHGVKVGDLVSVDFKGGSTAKLKVAAITSDDTNIDKGAMYVAVTTVAQYVPAEKMPKNTNMFAKAEDGKAQEAYAALKKSLAAYPQYTVRDQTDFKKDLKDQVGQLLNIVYGLLALAIIVAVLGVVNTLALSVVERTREIGLMRAIGLSRRQLRRMIRLESVVIALFGALLGLGLGMGWGATAHKLLALEGMGVLEIPWPTIGTVFVASAFVGLFAALIPAFRAGRMNVLNAIATD
>CP032698.1|AYG82388.1|5087980_5089435_-|hypothetical-protein
MSGVLLALPDTAARTGGEGPRADGGRAAPPHIRSRPAADPYLLAAALFAAYTTLSVLRYRRMETRSWDLGIFEQVVRAYAHLQAPVADLKGPGANVLGDHFSPVTALLAPAYRLFPTPVTLLVAQAALFALAAIPVTRAAARLLGRGPGLAIGAAFGLSWGIQRAVDFDFHEICFAVPLIAFGLEAVVRGRWRAALLYALPLTLVKEDLGLTTAALAVVVAVRARRTSPGAVRRAMLVAAFGTVATLITLTVVIPAFNSGVGYDYWSKMGGGGGPLAAWDVKVRTLLWTLVPTTGLLALRSPLLLVALPTLGWRFLSFDDHYWSTDWHYSAVLMPVLALALADAVATARTSPRPWLRSYARALPACAAAAALALTPSLPLAALTEHDTYRKSPQVAAVEGLLARIPDGATVEADIGPIARLTSRCRVFWVGAARPVLPRYIAIDNSDGWAGDPVQYATTLHPGAVYTVTGVAGGYVLLELGPHP
>CP032698.1|AYG82389.1|5089452_5089962_-|hypothetical-protein
MSDPHRDDRDDRNGRAEESLARALKRAADTAARAAAPEPAGHVTARGLRRRRRNLAALAACAVCLLAGSGAALGLRLQQGDPVPPASVPTNGSPSPGDGSGPPSLRPSPSFPSSSGSGSGSGSAPASASSSGSSSASASADSITATPSGLPPSFSPRSGSSVTPTTPAR

Crispr_ID: CP032698_60

• CRISPR_ID: CP032698_60
• CRISPR_location: 5118867-5118948
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_60

Consensus_repeat	Method
TCTCGCGCAGTTCCTCGCGCCCCTAA	CRISPRCasFinder

spacers of CP032698_60

>60.1|5118893|30|CP032698|CRISPRCasFinder
ACCCGCTTTCGGGTGCGGGCCGTGGTCGCT

CRISPR arrays and Neighbor proteins around CP032698_60

CRISPR arrays

The CRISPR arrays of CP032698_60

>merge|CP032698|60|5118867-5118948|CRISPRCasFinder
TCTCGCGCAGTTCCTCGCGCCCCTAAACCCGCTTTCGGGTGCGGGCCGTGGTCGCTTCTCGCGCAGTTCCCCGCGCCCCTAA

>CP032698|60|44|5118867-5118948|CRISPRCasFinder
TCTCGCGCAGTTCCTCGCGCCCCTAA	ACCCGCTTTCGGGTGCGGGCCGTGGTCGCT
TCTCGCGCAGTTCCCCGCGCCCCTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82408.1|5114843_5116136_+|putative-fatty-acid-methyltransferase	unknown	unknown	gnl|CDD|367049
CP032698.1|AYG82400.1|5105616_5106873_+|Cytochrome-P450-107B1	unknown	unknown	gnl|CDD|225035
CP032698.1|AYG82416.1|5125134_5125944_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82403.1|5109426_5110707_+|Enolase	unknown	unknown	gnl|CDD|234617
CP032698.1|AYG82412.1|5121525_5122722_-|Glucan-endo-1,3-beta-glucosidase	unknown	unknown	gnl|CDD|185753
CP032698.1|AYG82404.1|5110809_5111298_+|Cell-division-protein-FtsL	unknown	unknown	gnl|CDD|368217
CP032698.1|AYG82407.1|5113166_5114558_+|NADH-dehydrogenase-like-protein	unknown	unknown	gnl|CDD|224172
CP032698.1|AYG82418.1|5127714_5128728_-|hypothetical-protein	unknown	unknown	gnl|CDD|238874
CP032698.1|AYG82401.1|5107016_5108054_+|Resuscitation-promoting-factor-RpfA	unknown	unknown	gnl|CDD|369056
CP032698.1|AYG82414.1|5124402_5124633_-|hypothetical-protein	unknown	unknown	gnl|CDD|379478
CP032698.1|AYG82410.1|5119120_5119891_-|putative-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
CP032698.1|AYG82402.1|5108484_5109162_+|Resuscitation-promoting-factor-Rpf	unknown	unknown	gnl|CDD|369056
CP032698.1|AYG82405.1|5111328_5111862_+|hypothetical-protein	unknown	unknown	gnl|CDD|224424
CP032698.1|AYG82419.1|5128866_5130264_+|Putative-cystathionine-beta-synthase	unknown	unknown	gnl|CDD|273464
CP032698.1|AYG82406.1|5111858_5112797_+|Guanosine-5'-triphosphate,3'-diphosphate-pyrophosphatase	unknown	unknown	gnl|CDD|223326
CP032698.1|AYG82417.1|5126295_5127516_-|Acetyl-CoA-acetyltransferase	unknown	unknown	gnl|CDD|181146
CP032698.1|AYG82413.1|5122739_5124134_-|Glucan-endo-1,3-beta-glucosidase-A1	unknown	unknown	gnl|CDD|185691
CP032698.1|AYG82415.1|5124734_5125061_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82409.1|5116229_5118758_-|ABC-transporter-permease-YtrF	unknown	unknown	gnl|CDD|223650
CP032698.1|AYG82411.1|5120573_5121449_+|hypothetical-protein	unknown	unknown	gnl|CDD|378959

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82408.1|5114843_5116136_+|putative-fatty-acid-methyltransferase	gnl|CDD|367049	pfam02353, CMAS, Mycolic acid cyclopropane synthetase. This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.	6.37903e-117
CP032698.1|AYG82400.1|5105616_5106873_+|Cytochrome-P450-107B1	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	2.30503e-99
CP032698.1|AYG82419.1|5128866_5130264_+|Putative-cystathionine-beta-synthase	gnl|CDD|273464	TIGR01137, Cystathionine_beta-synthase, cystathionine beta-synthase. Members of this family closely resemble cysteine synthase but contain an additional C-terminal CBS domain. The function of any bacterial member included in this family is proposed but not proven. [Amino acid biosynthesis, Serine family].	0
CP032698.1|AYG82403.1|5109426_5110707_+|Enolase	gnl|CDD|234617	PRK00077, eno, enolase; Provisional.	0
CP032698.1|AYG82412.1|5121525_5122722_-|Glucan-endo-1,3-beta-glucosidase	gnl|CDD|185753	cd09214, GH64-like, glycosyl hydrolase 64 family. This family is represented by the laminaripentaose-producing, beta-1,3-glucanase (LPHase) of Streptomyces matensis and related bacterial and ascomycete proteins. LPHase is a member of glycoside hydrolase family 64 (GH64), it is an inverting enzyme involved in the cleavage of long-chain polysaccharide beta-1,3-glucans, into specific pentasaccharide oligomers. LPHase is a two-domain crescent fold structure: one domain is composed of 10 beta-strands, eight coming from the N-terminus of the protein and two from the C-terminal region, and the protein has a second inserted domain; this cd includes both domains. This protein has an electronegative, substrate-binding cleft, and conserved Glu and Asp residues involved in the cleavage of the beta-1,3-glucan, laminarin, a plant and fungal cell wall component. Among bacteria, many beta-1,3-glucanases are implicated in fungal cell wall degradation. Also included in this family is GluB , the beta-1,3-glucanase B from Lysobacter enzymogenes Strain N4-7. Recombinant GluB demonstrated higher relative activity toward the branched-chain beta-1,3 glucan substrate zymosan A than toward linear beta-1,3 glucan substrates. Sometimes these two domains are found associated with other domains such as in the Catenulispora acidiphila DSM 44928 carbohydrate binding family 6 protein in which they are positioned N-terminal of a carbohydrate binding module, family 6 (CBM_6) domain. In the Cellulosimicrobium cellulans, glucan endo-1,3-beta-glucosidase, they are positioned N-terminal of a RICIN, carbohydrate-binding domain, and in the Salinispora tropica CNB-440, coagulation factor 5/8 C-terminal domain (FA58C) protein, they are positioned C-terminal of two FA58C domains which are proposed to function as cell surface-attached, carbohydrate-binding domain. This FA58C-containing protein has an internal peptide deletion (of approx. 44 residues) in the LPHase domain II.	1.96425e-81
CP032698.1|AYG82404.1|5110809_5111298_+|Cell-division-protein-FtsL	gnl|CDD|368217	pfam04977, DivIC, Septum formation initiator. DivIC from B. subtilis is necessary for both vegetative and sporulation septum formation. These proteins are mainly composed of an amino terminal coiled-coil.	1.67402e-08
CP032698.1|AYG82407.1|5113166_5114558_+|NADH-dehydrogenase-like-protein	gnl|CDD|224172	COG1252, Ndh, NADH dehydrogenase, FAD-containing subunit [Energy production and conversion].	3.5529e-101
CP032698.1|AYG82401.1|5107016_5108054_+|Resuscitation-promoting-factor-RpfA	gnl|CDD|369056	pfam06737, Transglycosylas, Transglycosylase-like domain. This family of proteins are very likely to act as transglycosylase enzymes related to pfam00062 and pfam01464. These other families are weakly matched by this family, and include the known active site residues.	2.38038e-23
CP032698.1|AYG82414.1|5124402_5124633_-|hypothetical-protein	gnl|CDD|379478	pfam14117, DUF4287, Domain of unknown function (DUF4287). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 70 and 180 amino acids in length.	6.45319e-24
CP032698.1|AYG82410.1|5119120_5119891_-|putative-ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.49219e-110
CP032698.1|AYG82402.1|5108484_5109162_+|Resuscitation-promoting-factor-Rpf	gnl|CDD|369056	pfam06737, Transglycosylas, Transglycosylase-like domain. This family of proteins are very likely to act as transglycosylase enzymes related to pfam00062 and pfam01464. These other families are weakly matched by this family, and include the known active site residues.	2.10568e-34
CP032698.1|AYG82405.1|5111328_5111862_+|hypothetical-protein	gnl|CDD|224424	COG1507, COG1507, Uncharacterized conserved protein [Function unknown].	1.89133e-59
CP032698.1|AYG82406.1|5111858_5112797_+|Guanosine-5'-triphosphate,3'-diphosphate-pyrophosphatase	gnl|CDD|223326	COG0248, GppA, Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism].	1.54162e-88
CP032698.1|AYG82417.1|5126295_5127516_-|Acetyl-CoA-acetyltransferase	gnl|CDD|181146	PRK07851, PRK07851, acetyl-CoA C-acetyltransferase.	0
CP032698.1|AYG82413.1|5122739_5124134_-|Glucan-endo-1,3-beta-glucosidase-A1	gnl|CDD|185691	cd02182, GH16_Strep_laminarinase_like, Streptomyces laminarinase-like, member of glycosyl hydrolase family 16. Proteins similar to Streptomyces sioyaensis beta-1,3-glucanase (laminarinase) present in Actinomycetales as well as Peziomycotina. Laminarinases belong to glycosyl hydrolase family 16 and hydrolyze the glycosidic bond of the 1,3-beta-linked glucan, a major component of fungal and plant cell walls and the structural and storage polysaccharides (laminarin) of marine macro-algae. Members of the GH16 family have a conserved jelly roll fold with an active site channel.	2.13183e-123
CP032698.1|AYG82418.1|5127714_5128728_-|hypothetical-protein	gnl|CDD|238874	cd01836, FeeA_FeeB_like, SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases. FeeA and FeeB are part of a biosynthetic gene cluster and may participate in the biosynthesis of long-chain N-acyltyrosines by providing saturated and unsaturated fatty acids, which it turn are loaded onto the acyl carrier protein FeeL. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	3.75636e-48
CP032698.1|AYG82409.1|5116229_5118758_-|ABC-transporter-permease-YtrF	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	1.07901e-22
CP032698.1|AYG82411.1|5120573_5121449_+|hypothetical-protein	gnl|CDD|378959	pfam12811, BaxI_1, Bax inhibitor 1 like. The Bax-inhibitor-1 region of the receptor molecules is conserved from bacteria to humans.	1.04037e-84

Protein sequences

>CP032698.1|AYG82409.1|5116229_5118758_-|ABC-transporter-permease-YtrF
MFKTALRNVLAHKARLLMTVLAVMLGVAFVSGTLIFTDTLGSAFRNQSSKSYDKVAVAVSSYGSAEDTEREPGVSARTLQKMAALDGVASATGRVDGFAGVAGTDGKLIGQGWANKGGNFAPGKDGKDPSYTFVQGSGPVRDDQIALDKESADKGEYAVGDSVRVATNGPVRTYRLAGVFTTEDGQVNAGGSLVLFDTAVAQRLYLKPGYFQNVNLAATPGADAQKILDEVRPLLPKDADAKTGQVLADQEARSIKEALSGLNQMLLGFAGIALFVGIFLISNTFTMLVAQRTRELALMRAVGASRGQVRRSVLAEALVVGALASVIGFGLGLGLASGLRSVIDMFGAKMPAGPLIVTATPVIASLAVGILVTVVAALLPAWRAAKIPPVAAMNSVHGVATTKSLVVRNSIGGVITLAGAAAIVAGAATGKDGKYIIGAGAFFALIGIIILIPLLSRPVIALVRPGLSKVFGVSGKLASQNAVRNPRRTGATASALAIGLTLVTGLSVLGITVGTAIDKMTTDNLKADYLVQMAAGGSGLDPEVVSSLRKAPGVSAVSPKQPSYLKIGDSEQSVAGVTPDIDKLIKVEPVSGSLAALGRGQLAVDDETAAKHGWKAGSKLPVEFADKKKGELTIGATYKKSELIDSVLVPTSVLDAHQNKPYIPEVYVKVDGGASSAHEKALVDALGQNPAIKFMDRQDIRNEAGGMINTMLNVMYGLLAMALIIAVLGVINTLAMSVYERQQEIGMLRAIGLDRRRVKTMIRLEAVVISLFGAVIGIGLGSFLAWAIGQTIKESIPGYVLVMPWDRIAVFLLLAGLVGVLAAMWPARSAAKLNMLTAIKTE
>CP032698.1|AYG82408.1|5114843_5116136_+|putative-fatty-acid-methyltransferase
MADAALRLTALAEEVLGEALPIRIRAWDGSEAGPPGAPVLVVRHRRALRRLLWKPGELGLARAWVAGELDVEGDLYALLDRLSGLIWEREEEPGKRVHPVRDPRLRAAARELVKLGGALPPPAPPAEEVHRRTGRLHTRRRDKEAISHHYDVGNDFYALVLGPSMVYSCAYWESPESTLEEAQRDKLDLVCRKLALKEGDRLLDVGCGWGSMAIHAAREYGAHVVGITLSREQAAYARKRIAEEGLTDRIEIRVQDYRDVKDGPYDAISSIGMAEHVGSVRYAEYADILYGLLRDGGRLLNHQIARRPERDESAYHIDEFIDAYVFPDGELAPVGRTVSTLEEAGFEARDVEPIREHYALTLRQWVANLESDWPRAVRHTSPGRARIWRLYMAACALSFERNRIGVNQILAVKTPVSGASGMSLRARTWN
>CP032698.1|AYG82407.1|5113166_5114558_+|NADH-dehydrogenase-like-protein
MSTTERPRILVVGGGYVGLYAARRILKKMRYAEATVTVVDPRSYMTYQPFLPEAAAGSISPRHVVVPLRRVVRGAEVLTGRVTSIDQDRKVATVAPLVGEAYELPFDYLVIAMGAVSRTFPIPGLAEQGIGMKGVEEAIGLRNHVLEQLDKADSTTDEDVRRKALTFVFVGGGFAGAETIGEVEDMARDAAKYYTNVKREDMRFILVDAADKILPEVGPELGRWGKEHLEGRGVEIYLSTSMDSCVDGHVVLKNGLEVDSNTIVWTAGVKPNPALSRFGLPLGPRGHVDAQPTLQVTGTDYIWAAGDNAQVPDLASRKAGVENAWCPPNAQHALRQAKVLGDNVVSGMRGFPQKEYSHANKGAVAGLGLHKGVAMIVMGKMKIKLKGRLAWYMHRGYHGLAVPTWNRKIRVIADWTLAMFLKREVVSLGAMETPREEFYEAAKPAPAPAAKVEDKKEQKAKAS
>CP032698.1|AYG82406.1|5111858_5112797_+|Guanosine-5'-triphosphate,3'-diphosphate-pyrophosphatase
MTRVAAIDCGTNSIRLLVADATVSDSASGAGTTGHITDLDRRMTIVRLGQGVDRTGRLAPEALERTFAACREYAAVIKELGAERVRFVATSASRDAENREEFTRGVLDILGVEPEVISGDQEAEFSFTGATKELPGDGDYLVVDIGGGSTEFVVGSSGVEAARSVDIGCVRMTERHHPGDPATPEQIAAIRADIEAALDLAEATVPLREPRTLVGLAGSVTTIAAISLGLTGYDSAAIHHSRISHEEVAAITGRLLASTHEERTAIPVLHPGRIDVIAAGALVLLAVMERTGAREVVVSEHDILDGIAWSIA
>CP032698.1|AYG82405.1|5111328_5111862_+|hypothetical-protein
METPPPQTERTEPTDADIAAFKQQLGRPPRGLRAIAHRCPCGNPDVVETAPRLEDGTPFPTTYYLTCPRAASAIGTLEANGVMKDMTERLASDPELAAAYRAAHEDYIARRDAIEVLEGFPSAGGMPDRVKCLHVLVGHSLAAGPGVNPLGDEAIALLPEWWAKGPCVTPCGEGDEK
>CP032698.1|AYG82404.1|5110809_5111298_+|Cell-division-protein-FtsL
MGKEAKVKDRDRFSTAARLKVLGEQTAARVYRSQNKRQARRSRLTGRAALLALVLCSLIVALAYPMRQYVSQRGDIADQQRKAADAQQAVERLRDEKARLQDDAYIEKLAREHLHMQFPGESGFTVVDPGAANKHREDKGATGRAWHSNLWDGVDKADRSAN
>CP032698.1|AYG82403.1|5109426_5110707_+|Enolase
MPSIDVVVAREILDSRGNPTVEVEVGLDDGSTGRAAVPSGASTGAFEAIELRDGDPNRYGGKGVEKAVLAVIEQIGPELVGYDATEQRLIDQAMFDLDATDNKGSLGANAILGVSLAVAHAASEASDLPLFRYLGGPNAHLLPVPMMNILNGGSHADSNVDIQEFMIAPIGAESFSEALRWGAEVYHTLKGVLKRKGLSTGLGDEGGFAPNLESNRAALDLIVEAIKEAGYAPGKDVALALDVAASEFYKDGKYEFEGKSRSAAEMTEYYEELVAAYPLVSIEDPLFEDDWAGWNTITSRLGSKVQIVGDDLFVTNPERLARGIEEGSANALLVKVNQIGSLTETLDAVEMAQRNGFKCMMSHRSGETEDVTIADLAVAVNCGQIKTGAPARSDRVAKYNQLLRIEEILDDAAVYAGRSAFPRFKG
>CP032698.1|AYG82402.1|5108484_5109162_+|Resuscitation-promoting-factor-Rpf
MLLSGKGKHRRPSKAVRVATLAGVTGVAVAAPLMAAGNASAASVSTWDAVAQCESGGNWSINTGNGYYGGLQFSQSSWAAAGGTQYASRADLATKGQQIAAAEKLLAIQGPGAWSCAGAGNLTSGGSKADVDTSGSSAAKPSKPKAAPQQKSQRVESAPKASRSEQRSEPVKQGDGEYTVKSGDTLGTIATANSTKGGWQHLFELNKDIVKDANLIFPGQKLHLG
>CP032698.1|AYG82401.1|5107016_5108054_+|Resuscitation-promoting-factor-RpfA
MRSGNGRHRRPRQAPALVVAAGVTGSALALPLLAATGANAADANTWNEVAACESGGLWSADFGNGLYGGLQFSQATWEAYGGNEYAQRADLASRAQQIAVAEKVLAAKGAQAFANCGTGAGLAKGGGAADVDPGVPSAPTGTASPVPTAPATKAPDTTPAPGGSTPAKTSPDALPPSGPVKSPAPSGSTPEGAGKHRGTPAPEESAGATSRGTGTDAPAGSSGSTAPAGSAGSTGSAGSGSGAAGDAAPNRDSGQHASRGDGASREAGNAPAASGDYTVRPGDNLSAIAEANKVQGGWPALYHANEQLIGTDPNLILPGQSLALTEVKGAPTTAAPAPNSAPKQG
>CP032698.1|AYG82400.1|5105616_5106873_+|Cytochrome-P450-107B1
MQHEADAPLPPAPELFTWEFATNPYPAYAWLRTHAPVHRTRLPSGVEAWLVTRYGDAKQALADQRLSKNPAHHDEPAHAKGKTGIPGERKAELMTHLLNIDPPDHTRLRRLVSKAFTPRTVAQFAPRVQELTDQLIDAFAAEGEADLIHEFAFPLPIYAICDLLGVPREDQDDFRDWAGMMIRHGGGPRGGVARSVKKMRDYLAELIHKKRENPGDDLISRLIEASDHGEHLTENEAAAMAFILLFAGFETTVNLIGNGMYALLRDPGQRERLQASLAAGESDLLETGVEELLRFDGPVELATWRFAVEPLTLGGQDIAAGDPVLVVLAAADRDPDRFDDPDTLDLGRRDNQHLGYGHGIHYCLGAPLARLEGQTALATLLRRLPDLRLAVEPEDMRWRGGLIMRGLRTLPVAFTPPR
>CP032698.1|AYG82410.1|5119120_5119891_-|putative-ABC-transporter-ATP-binding-protein
MTTIPTAHRATAVAARAIELSKVYGTGETQVVALDQVTVDFRQGEFTAIMGPSGSGKSTLMHCVAGLDSFSSGAVRIGETELGSLKDKQLTQLRRDKIGFIFQAFNLLPTLTALENITLPMDIAGRKPNKQWLDQVISMVGLADRLSHRPTQLSGGQQQRVAVARALASQPEIIFGDEPTGNLDSRSGAEVLGFLRNSVRELGQTVVMVTHDPVAASYADRVIFLADGRIVDEMLRPSADGVLDRMKAFEAKGRTS
>CP032698.1|AYG82411.1|5120573_5121449_+|hypothetical-protein
MRSSNPVFSRRGFSRDNGYAGFNTAQQPQAGGNPYAQAPTNPYATNPYAQQDTQQGVPQAPARSGAMTIDDVVSRTAITLGTVVAGAVVAWLALPVDAANVNKSYGIAIGAALIAFVLAMVQSFKRRPTPALILGYAAFEGVFLGVISSVVTTYVSAGAVPQAVLGTMAVFAGVLIAYKTRLIRVNRRFTGFVMAAAIGFMLLMLVNLLFSAIGGGDGLGFRSGGLGILFGIIGIVLGACFLALDFKQVEDGITYGAPREESWLAAFGLTMTLVWIYLEALRLISILQGND
>CP032698.1|AYG82412.1|5121525_5122722_-|Glucan-endo-1,3-beta-glucosidase
MKTVRLLLAAATTSALLLLGAGTTTATASDAPGTAAAGFPIVFQNNTHGAYADAQIHITVLGQITPGQWSYLKPDGTTAHINHLDANAPGHLTKHGVNYPNMSFTLAQVGGRVPSPSSIRGGRIYLSLGSPLYIPVSPDDQGWGGPDPNNPSDPNNDVYYDWYEYTFVNGQAAYGGNTTQVDQFGFPMTARLRQTSSGYDTTRGISRSRAEVMSAYASSVGAAFQPLRSAYRIVAPRSAAAFPADYLTATVNDTWSYYASHPFTLSLPGETLSGRVAGDTLTFTRNGAGPYTLRRPTSREVMACSGALASGSDVEKRLGAEFCAAFNRGVAQNTALWHTPSAYYPGTTPKNDYAAFFHTVGLAGRAYGFPYDDINDQSSVQILGNAAPPTELTLSIGW
>CP032698.1|AYG82413.1|5122739_5124134_-|Glucan-endo-1,3-beta-glucosidase-A1
MRPTPHRRGPARRALVAVLSTLGLAAASAAVVALPASASAPPPPAGWSTVFSDDFNGPAGSGVDTANWQYTTGTSYPGGPANFGTGEVETMTSSTNNVALDGAGNLRITPQRDASGHWTSGRVETRRSDFQPPAGGKLRIESRLRMPDVTGAAAKGYWPAFWALGAPFRGNWWNWPGIGELDIMENVQGLNNNWSTMHCGTSPGGPCNETTGIGGQKACDGSTCQGGFHTYAVEWDRSGSVEQMRFYLDGVNFHTVNQNQVSAATWTNATNHGYFVILNVAMGGGFPDAFGGGPDAGTQPGHSLVVDYVTVLQAGSGTTPPTTPPTGNRDAYGTLQAESYDQQSGVVKEATTDSGGGQDIGSLANGDWALYKGVAFGSTPARQFSARVASGAAGGVSGLVEVRLDSPSSAPVGSFALANTGGWQSWRTVPANISGVTGTHDVYLTFTSGQGADFVNVNWFTFGH
>CP032698.1|AYG82414.1|5124402_5124633_-|hypothetical-protein
MSQVFSDETHRNLLSRIPHCTGREVSDWLRTVEEGPSLCRFEEKVRWLRSEHDLAYGHAKAIIHEYDLRRAARRLL
>CP032698.1|AYG82415.1|5124734_5125061_+|hypothetical-protein
MLDVNPLILAVDRFADRLRAAPESRLRRGAAAEALALARELALLAQRVEDPAREPLAMPDAGVFAVADQVMVAGRDLAQALHHAKTPPGGEPDGAVKRVEAAEERAFG
>CP032698.1|AYG82416.1|5125134_5125944_-|hypothetical-protein
MSAMPLALLLTTAAATAVGAAALHAAHGLRRQVVALREDLAAARAEHRADTAVTLPQQARSAATPAAEIRAAVAEALAEERERELAEARAFWAAQEARDAADAPSPMLGGLAGLGEDAAFFLPRQADFVGLEAEALELAEEFPEDSPELAAARRRHPSHPDFVPVQTPVVADHEATVSRLEELAESRTALADVRPGPLGTLDVYVFADGTTLCMTPGHRETAERLSDALRDGEAPVLLGGSGVSGAYALTFSCGEESVYILADRVIASL
>CP032698.1|AYG82417.1|5126295_5127516_-|Acetyl-CoA-acetyltransferase
MPEAVIVSAARSPIGRAFKGSLKDLRPDDLTATIIEAALAKVPGLDPRDIDDLMLGCGLPGGEQGHNLGRIVAVQMGMDHLPGCTITRYCSSSLQTSRMALHAIKAGEGDVFISAGVEMVSRSVKGSSDGLPDTHNPFFADAEARTAAVAQSEGSDWHDPREDGLVPDAYIAMGQTAENLARLKGISRREMDEFGVRSQNLAEEAIKNGFWEREITPVTTPDGTVVSKDDGPRAGVTLEGVEGLKPVFRPDGLVTAGNCCPLNDGAAALVIMSDTKARELGLTPLARIVSTGVTGLSPEIMGLGPVEASRQALKRAGLTVDDIDLFEINEAFAAQVIPSYQDLGIPLDKLNVNGGAIAVGHPFGMTGARLTGTLINSLQFHDKQFGLETMCVGGGQGMAMVIERLS
>CP032698.1|AYG82418.1|5127714_5128728_-|hypothetical-protein
MAGTGSRARAARRIATGAAFGGGGIGLIAGAAVGVVLAEVALAKRSVGSGSPQAPNADGLYGTAFADGTPPLRLGMLGDSTAAGQGVRRAGQTPAALLASGLAAVAERMVTLRNVALPGARSDDLERQVSLLLADPDRLPDVCVIMIGANDVTTRMAPTTSVRYLSTAVRRLRTAGAEVVVGTCPDLGTIEPVYQPLRWLARRVSRQLAAAQTIVVVEQGGRTVSLGHLLGPEFAANPRELFGPDNYHPSAEGYATAAMAVLPTLCAALGLWPESDHPDASRNEDILPVAKAASAAAAQAGTEVTGVRAPWALLKYRRRRRLPAPVEPTPNGSRTGP
>CP032698.1|AYG82419.1|5128866_5130264_+|Putative-cystathionine-beta-synthase
MRFHDSMISLVGNTPLVRLNSVTQGIQATVLAKVEYFNPGGSVKDRIAVRMIEAAEQSGALKPGGTIVEPTSGNTGVGLAIVAQQKGYKCIFVCPDKVSTDKINVLRAYGAEVVVCPTAVDPEHPDSYYNVSDRLVRETPGAWKPDQYSNPNNPRSHYETTGPELWEQTEGKITHFVAGVGTGGTITGTGRYLKEASDGKVRIVGADPEGSVYSGGSGRPYLVEGVGEDFWPTAYDQSVTDEIVAVSDKDSFQMTRRLAKEEGLLVGGSCGMAVVAALRVAEGLGPDDVVVVLLPDSGRGYLSKIFNDEWMADYGFLEEAGPSARVSDVLGFKEHGHLPSLVHMHPEETVGQAIEVLREYGVSQMPIVKPGAGHPDVMAAEVIGSVVERELLDALFTQRALLDDPLEKHMSSPLPQVGSGEPVGDLMSVLGKADAAIVLVEGKPTGVVSRQDLLAFLARTPQQVP

Crispr_ID: CP032698_61

• CRISPR_ID: CP032698_61
• CRISPR_location: 5182523-5182621
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_61

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGGGG	CRISPRCasFinder

spacers of CP032698_61

>61.1|5182549|47|CP032698|CRISPRCasFinder
CCGAACCCTTCAACGCGCTGCACGGGCGGGTGGGTGGGCAAACGCGT

CRISPR arrays and Neighbor proteins around CP032698_61

CRISPR arrays

The CRISPR arrays of CP032698_61

>merge|CP032698|61|5182523-5182621|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGCCGAACCCTTCAACGCGCTGCACGGGCGGGTGGGTGGGCAAACGCGTCGGGGTCTGGGGCGGAGCCCCAGGGG

>CP032698|61|45|5182523-5182621|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGG	CCGAACCCTTCAACGCGCTGCACGGGCGGGTGGGTGGGCAAACGCGT
CGGGGTCTGGGGCGGAGCCCCAGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82472.1|5185955_5186498_-|Cysteine-dioxygenase	unknown	unknown	gnl|CDD|380416
CP032698.1|AYG82474.1|5187726_5191533_+|N-acetylglucosaminyl-diphospho-decaprenol-L-rhamnosyltransferase	unknown	unknown	gnl|CDD|224137
CP032698.1|AYG82473.1|5187204_5187468_+|Transcriptional-regulator-WhiB	unknown	unknown	gnl|CDD|376791
CP032698.1|AYG82460.1|5169937_5170462_+|putative-acyl-CoA-thioester-hydrolase	unknown	unknown	gnl|CDD|224523
CP032698.1|AYG82475.1|5191529_5193098_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82476.1|5193193_5193595_-|hypothetical-protein	unknown	unknown	gnl|CDD|240574
CP032698.1|AYG82466.1|5178771_5179524_-|hypothetical-protein	unknown	unknown	gnl|CDD|274426
CP032698.1|AYG82461.1|5170491_5171979_-|Putative-transcriptional-regulator-YwtF	unknown	unknown	gnl|CDD|367673
CP032698.1|AYG82477.1|5193954_5194374_+|hypothetical-protein	unknown	unknown	gnl|CDD|378788
CP032698.1|AYG82459.1|5168532_5169831_-|Putative-transcriptional-regulator-YvhJ	unknown	unknown	gnl|CDD|367673
CP032698.1|AYG82465.1|5177093_5178587_-|Putative-transcriptional-regulator-YwtF	unknown	unknown	gnl|CDD|367673
CP032698.1|AYG82478.1|5194554_5195916_+|Phosphomannomutase/phosphoglucomutase	unknown	unknown	gnl|CDD|236557
CP032698.1|AYG82471.1|5184954_5185911_-|2-phospho-L-lactate-transferase	unknown	unknown	gnl|CDD|237443
CP032698.1|AYG82467.1|5179635_5181003_+|hypothetical-protein	unknown	unknown	gnl|CDD|128941
CP032698.1|AYG82463.1|5173264_5175070_-|Putative-transcriptional-regulator-YwtF	unknown	unknown	gnl|CDD|367673
CP032698.1|AYG82468.1|5181112_5182195_+|UTP--glucose-1-phosphate-uridylyltransferase	unknown	unknown	gnl|CDD|224129
CP032698.1|AYG82470.1|5183665_5184958_-|Coenzyme-F420:L-glutamate-ligase	unknown	unknown	gnl|CDD|183957
CP032698.1|AYG82469.1|5182670_5183642_+|DNA-3-methyladenine-glycosylase	unknown	unknown	gnl|CDD|223200
CP032698.1|AYG82462.1|5172129_5173131_+|Beta-monoglucosyldiacylglycerol-synthase	unknown	unknown	gnl|CDD|133016
CP032698.1|AYG82464.1|5175127_5176864_-|Putative-transcriptional-regulator-YwtF	unknown	unknown	gnl|CDD|367673

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82472.1|5185955_5186498_-|Cysteine-dioxygenase	gnl|CDD|380416	cd10548, cupin_CDO, cysteine dioxygenase, cupin domain. This family contains cysteine dioxygenase (CDO; EC 1.13.11.20), which catalyzes the conversion of cysteine to cysteine sulfinic acid, the first step in the biosynthesis of essential oxidized cysteine metabolites such as sulfate, hypotaurine, and taurine. CDO also plays an important role in the regulation of intracellular cysteine levels in mammals; CDO expression is altered in cancer cells, and abnormal or deficient CDO activity has been linked to Parkinson's disease, Alzheimer's disease, and rheumatoid arthritis. CDO is an iron-dependent thiol dioxygenase that uses molecular oxygen to oxidize the sulfhydryl group of cysteine to generate cysteine sulfinic acid. The CDO active site contains an amino acid-derived cofactor. These enzymes are found in prokaryotes as well as eukaryotes and belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.09263e-20
CP032698.1|AYG82474.1|5187726_5191533_+|N-acetylglucosaminyl-diphospho-decaprenol-L-rhamnosyltransferase	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	2.48304e-34
CP032698.1|AYG82473.1|5187204_5187468_+|Transcriptional-regulator-WhiB	gnl|CDD|376791	pfam02467, Whib, Transcription factor WhiB. WhiB is a putative transcription factor in Actinobacteria, required for differentiation and sporulation.	5.22363e-28
CP032698.1|AYG82460.1|5169937_5170462_+|putative-acyl-CoA-thioester-hydrolase	gnl|CDD|224523	COG1607, COG1607, Acyl-CoA hydrolase [Lipid metabolism].	1.71436e-48
CP032698.1|AYG82476.1|5193193_5193595_-|hypothetical-protein	gnl|CDD|240574	cd12954, MMP_TTHA0227_like_1, Minimal MMP-like domain found in a group of hypothetical proteins from alphaproteobacteria and actinobacteria. The subfamily includes some uncharacterized bacterial proteins which show high sequence similarity with Thermus thermophilus hypothetical protein TTHA0227. However, they do not contain the conserved HExxH (x could be any amino acid) motif. They may not have any zinc metallo-peptidase activity.	1.02712e-27
CP032698.1|AYG82466.1|5178771_5179524_-|hypothetical-protein	gnl|CDD|274426	TIGR03089, conserved_hypothetical_protein, TIGR03089 family protein. This protein family is found, so far, only in the Actinobacteria (Streptomyces, Mycobacterium, Corynebacterium, Nocardia, Propionibacterium, etc.) and never more than one to a genome. Members show twilight-level sequence similarity to family of AMP-binding enzymes described by pfam00501.	1.79946e-70
CP032698.1|AYG82461.1|5170491_5171979_-|Putative-transcriptional-regulator-YwtF	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	5.65878e-57
CP032698.1|AYG82477.1|5193954_5194374_+|hypothetical-protein	gnl|CDD|378788	pfam12005, DUF3499, Protein of unknown function (DUF3499). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 125 to 163 amino acids in length.	7.25901e-58
CP032698.1|AYG82459.1|5168532_5169831_-|Putative-transcriptional-regulator-YvhJ	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	3.44081e-59
CP032698.1|AYG82465.1|5177093_5178587_-|Putative-transcriptional-regulator-YwtF	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	4.95379e-60
CP032698.1|AYG82478.1|5194554_5195916_+|Phosphomannomutase/phosphoglucomutase	gnl|CDD|236557	PRK09542, manB, phosphomannomutase/phosphoglucomutase; Reviewed.	0
CP032698.1|AYG82471.1|5184954_5185911_-|2-phospho-L-lactate-transferase	gnl|CDD|237443	PRK13606, PRK13606, LPPG:FO 2-phospho-L-lactate transferase; Provisional.	3.83675e-174
CP032698.1|AYG82467.1|5179635_5181003_+|hypothetical-protein	gnl|CDD|128941	smart00701, PGRP, Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. The bacteriophage molecule, but not its moth homologue, has been shown to have N-acetylmuramoyl-L-alanine amidase activity. One member of this family, Tag7, is a cytokine.	4.85412e-50
CP032698.1|AYG82463.1|5173264_5175070_-|Putative-transcriptional-regulator-YwtF	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	1.61806e-50
CP032698.1|AYG82468.1|5181112_5182195_+|UTP--glucose-1-phosphate-uridylyltransferase	gnl|CDD|224129	COG1208, GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis].	1.75094e-100
CP032698.1|AYG82470.1|5183665_5184958_-|Coenzyme-F420:L-glutamate-ligase	gnl|CDD|183957	PRK13294, PRK13294, F420-0--gamma-glutamyl ligase; Provisional.	0
CP032698.1|AYG82469.1|5182670_5183642_+|DNA-3-methyladenine-glycosylase	gnl|CDD|223200	COG0122, AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair].	7.78613e-26
CP032698.1|AYG82462.1|5172129_5173131_+|Beta-monoglucosyldiacylglycerol-synthase	gnl|CDD|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	2.24101e-87
CP032698.1|AYG82464.1|5175127_5176864_-|Putative-transcriptional-regulator-YwtF	gnl|CDD|367673	pfam03816, LytR_cpsA_psr, Cell envelope-related transcriptional attenuator domain.	3.87471e-51

Protein sequences

>CP032698.1|AYG82468.1|5181112_5182195_+|UTP--glucose-1-phosphate-uridylyltransferase
MTEAILLVGGKGTRLRPLTVNTPKPMVPAAGVPFLTHQLARARAAGVDHIVLATSYLAEVFEPYFGDGSALGLSLEYVTEHEPLGTGGAIRNVASRLRSGPDEPVLIFNGDILTGLDIRALVDTHDASGADVSLHLTRVDDPRAFGLVPTDATGRVTAFLEKPQTPEEIVTDQINAGAYVFRRSVIDEIPQGRPVSVERETFPGLLARGAHLQGMVDSTYWLDLGTPQAFVRGSADLVLGRAPSPAVPGRCGDRLVLPTARVAPDAKLTGGTVVGRGAVVGEGARIVGSAILSDAVVAPGAVITDSLVGVGARIGARTVLEGAVVGDGAVVGPDNELCAGARVWCDAVLPAGALRFSSDQ
>CP032698.1|AYG82467.1|5179635_5181003_+|hypothetical-protein
MTTIVTMRSFLASSIGVAAVAALAVPLASTAPVAAASAVASPASAELAGSTQSLPMGPLPDTDRAAGGAAQEGLARREVRPFSLVGVVWDNADAELHGSVQVRTRSRAGGTWSPWQDLETHNHDHAADPGTAEAERPLHGSTAPLWVGDSDAVEAHVRPDDPEGELPGGLRLDLVDPGTGPAGSDDGARSLREPDVLPALDQAESRTEAEAEAGAGTGEEAGAGGMIRTGEMAGAGEVVAAGEAVGAAEPARPYIGARPRIVTRKGWGADERLRERGFVYTKSVKVAFVHHTASGNGYNCAQSASVLRSIYRFHVKSSGWRDIGYNFAVDKCGNIYEGRAGGVSKAVLGAHTLGFNTNSTGIAVLGTYTRTSPTAAALKAVEQLAAWKLGLYGVNPAGKSTLVSGGGNRYKKGRSVRFNAIAGHRDGFSTDCPGARLYGRLGAARVTAAHYQGRR
>CP032698.1|AYG82466.1|5178771_5179524_-|hypothetical-protein
MNASDRTPADLLRSALAADPGRPLITFYDDATGERVELSVATFANWVAKTANLLQGDLAAAPGDRLALLLPAHWQSAVWLMACHSVGVTVESGGDPAAADLVVTGPDTLEEARACTGERVALALRPLGGRFPQPPAGFVDYAVEVPGQGDRFVPFSPVDPDAPALAVDGAELSAAELVTRARAEAAALGLDAGARLLSARAYDTWAGLASGLYAPLASGGSVVLCRNLAQLADGGLEKRIESERVTQRAL
>CP032698.1|AYG82465.1|5177093_5178587_-|Putative-transcriptional-regulator-YwtF
MDAEVTDSAGTHPDPEDRAGAEQPPPAPGTPKAANRSNTNPATDPGPGPENEATAAKATAPGGTDPDPENQASASEPAPGGTDPEPDTEAAAASEPTPSGTDPGTHAKRRRHWLRWTALGVSVVVLAAAGTGWWFYRKLDGNIHTDTSAASELDKYERDRPVSVVHDAENLLLIGSDSRAGSNSSYGRDDGGSQRSDTTILLHLAADRLSATAVSLPRDLMADLPACGRPDGTTSRAQFAQFNSAFEIGGAACTIRTVEKMTGVRIDHHMVVDFSGFKDMVDAVDGVEVCLKEPVEDRQAHLKLPAGRQTLHGEQALGFVRSRHGFGDGSDTQRMDRQQQFLGSLVKKVQSNGVLLNPTRLYPVLDAATKSLTTDPGLNTLKDLYDLVSSMRDIPTQNIRFLTVPRQPYVYNGDRDELVQPDADRLFQQLRDDQPIKVAPAGDVAKLKEGGGKDRDGKGGDGKDRDGDGKPDDPGPTPSPSAPPVYSGTDAASGMCG
>CP032698.1|AYG82464.1|5175127_5176864_-|Putative-transcriptional-regulator-YwtF
MDAQSRGRADEVDPADQWVLNPETGTYELRLSPSGTQSKPGPNRSSADPTSTRTAEQSGRSGRREVPGQRNRRAGKSPAGEAPDAQGRRKRKPKATRKKKALLWTGGVMGFVLVVGAGGAYWLYQHFNDNLNTVDVGDAGSKSSVPDGAFNVLVIGTDKRTGKGNEGYGDAGSEGHADTNILFHVSADRTNATAMSIPRDMVTDIPACPTKQPDGTTKTIPGTKNARFNTSLGQEGRDPGCTMRTVKQLTGLTVDHFMMADFNAVKELSTAVGGVKVCLAKPVDDPKSHLKLPAGQSVVKGEQALAFVRTRHSFGNESDLDRIKQQQQFIGSMIRQMKSDDTLGSPTKMYGLADAATKALTVDSGIGSIKKLTDLAQVIGKIDAKNITFATLPVIDNPAEGKKHITVVPDPTKAEALFAMMRADTSLTEVKKKEADAKSSAAAEEAARLNGPRSKASEVRVTVLNGGAVAGSAGDMVTWLQNQQGVLKSSNGSNAPQKVPATVLAYAPNQADQARKLADLLGLSGAALKPGTKDAVGKEPMVLTLGPDFKQAGTPVAAPAKAPEGIQKVEADKSVCAK
>CP032698.1|AYG82463.1|5173264_5175070_-|Putative-transcriptional-regulator-YwtF
MGKNSVRGEGTARGRVEHAGELGWDESLYGNDAADGASGASKGAKPAGATETGGSRGSKGSGGSRGSGGSAAPGGSGTPSGPGDGGGSADSASGSGHRRGGSRRRGKRKHRVLRWTAITLAVLILGTATAGYLYYQHLNNNIRKGDRSAGGSDAKKAAPNAQGQTPLNILLIGSDSRKSDENVALGGAKDDRAGDPHADVQMLLHVSADRKNASVVSIPRDTRVNMPPCKDPEKKKDYPATNAIINEALGRGGAGCVLDTWEKLTGIYIDHWMMVDFAGVVAISDAVGGADVCVKQNIDDHSTKQQKGGSHLHLTAGNHTVKGEQALQWLRTRHAFGSDIGRSQAQHMYMNSVIRNLKDQDAFSDTGRLMDIAETATKSLQVSSELGTVKKLFDLGMELKNIPMDRINMLTMPRLPDPKDPNAHVVPDTAKADALWAMLRDDKPLDGKNDGKPASEAPKGPAAEAAGSLAVSVVNGTGTNGRVAVKGRASEVVSALKAKGFTQAATGSSDPTATSEVDYPKAAGAQGKANAQSVAAALGLPAGAVKPTDVKTLTLVVGGDWRTGASYPKQDPKATDPLKDTEAVNGADKGACMEVYAPYRF
>CP032698.1|AYG82462.1|5172129_5173131_+|Beta-monoglucosyldiacylglycerol-synthase
MPVLNEERHLRNSVRHILEQEYDGEMEVVIALGPSTDRTDEIAAELVRETASNERARVHTVPNPTGRTPAALNAAIKASRHPIVVRVDGHGMLSQNYIATAVRLLEETGAQNVGGIMHAEGENAWEDAVAAAMTSKIGVGNAAFHTGGEAGPAETVYLGVFRREALEQQGGYNEEFIRAQDWELNFRIREAGGLIWFSPELKVQYRPRPSVKALAKQYKDYGRWRHVVARYHAGSINLRYLAPPTAACAIAAGVVVGALVTPWGFVVPAGYLAAIVAGSLPAGKGLSLKARAQIPVALATMHMSWGFGFLTSPKALARKVIASRRPAVRTASV
>CP032698.1|AYG82461.1|5170491_5171979_-|Putative-transcriptional-regulator-YwtF
MPTPPRPRSVRPGRPPSRQQDERPRWGMRLATTLSVLVLGAGGVGHAVVTSLDGGIGRVDPFRDMKNRPQGSLGTNILLVGTDGRDKITPEEKQKYRLGGAPCHCTDTIMIVHVSADRDRVSVVSLPRDSYAEVPEHTDEATGHNHPRHPVKLNAAYAEGGPSLTVRTVEGMTGLKIDHYLEVDFTSFMKTVDVVGGVQICTARPMKDSYTGLDLGAGTHELNGGEALQYVRSRHADGSSDLGRMQRQQRFLAALIEKATSNGVLLNPVKFREVASSLLSSVRADEGFGVEEMLGFTAAMKGFTPSSSDFTTVPLGQLGFAVKGVGSTVKWDEVKAKKLFQLLHDDKPLAPHAPPKPTPQPATKDAKPPRAPGSIVEVAPEQIRVQVYNGTRTDGLGRRVDDGLRATGFKTTGSPRASTNLDMRRTLIEYDPRWDRSAESLALALPGSELRPVKGLGATMKVTAGADFKDVVPVRAEEQPQGDFGTVTGDRVVCP
>CP032698.1|AYG82460.1|5169937_5170462_+|putative-acyl-CoA-thioester-hydrolase
MTDLPGKPTSASRTTLSHIMTTHDTNLLGTVHGGVIMKLVDDAAGAVAGRHSGGPAVTASMDEMAFLMPVRVGDLVHVKAQVNWTGRSSMEVGVRVLAERWNESTPAQQVGSAYLVFAAVDADGKPRTVPPVIPETERDERRYQEAQIRRTHRLARRRAIMDLREKRSAEGLDD
>CP032698.1|AYG82459.1|5168532_5169831_-|Putative-transcriptional-regulator-YvhJ
MLDGMNEWPDARDGDARGNGDDGYGRGSSAARPEGARRMPHVQRPVPQQQPAYDDGYGQPRYGQGGVPGQGSYDSGYSEGHVYGSGRGPAGPGGPEGPRRGGARRPGAAPNWRRRITIGALTLVGVLLVTSVATYFWADGKVRREVDLSKVIERPDEGKGTNYLIVGSDSRDGMSAEEKKKLHTGSADGKRTDSMILLHVGDHGNTMVSLPRDSWVKIPSFKGSQSGKVFPAKGSNKLNAAFSMDGPELLVRTIEANTGLHIDHYAEIGFAGFANIVDAVGGVDIDIPQDIKDKDSGADFKKGKQTLDGQQALAFVRNRHGYAAGDLERTKNQQKFLAALASQTATPTTVLNPFKLYPVMGAGLDTLIVDKDMSLFDLGSMFWAMKGITGGDGVSMNMPVAGDGPQTSLLWDKPKVTQLVNELKNDDTVTVK
>CP032698.1|AYG82469.1|5182670_5183642_+|DNA-3-methyladenine-glycosylase
MAGRFTPRTPTPHQPAAGARVPGRKRTWAARSGPLDLALTLGPLRRGPGDPTYRTTPDGAVWRTSRTPAGPATLRVTAAGDTAHAEAWGAGAEWMLEQLPAMLGELDDPEAFEPRHRLLAETHRNRPGLRLTRTGLVLESLIPSVLEQKVTATEAYRAWRLLVRGFGEPAPGAPEGMYVMPDARQWALIPSWEWHRAGVDSKRSDTVMRAVRVARRMEEAAAMDPKDAEARLRLIPGIGPWTAAETLQRAIGAADLVTVGDLHLPGIIGHALAGNRNADDDEMLALLEPYAGQRHRAARLILLSGRVPPRRAPRFQPNNIAVL
>CP032698.1|AYG82470.1|5183665_5184958_-|Coenzyme-F420:L-glutamate-ligase
MSPASFRVWAVPGLPEVGAGDDLAKLIAAAEPGLADGDILLVTSKIVSKAEGRITEAADREAAIDAETVRVVARRGTLRIVENRQGLIMAAAGVDASNTPAGTVLLLPEDPDASAAAIRAGLRDALGVEVGVIVTDTFGRPWRNGLTDVAIGASGVRVLDDLRGGTDGHGNPLSATVISLADELAAAGDLVKGKAGGLPVAVVRGLGHLAGDGSAREMVRAAADDMFRLGTSEAVREAVTQRRTVRAFTDEPVDSGAVRRAVAAAVTAPAPHHTTPWRFVLLESAESRTRLLDAMRDAWIADLRRDGKSEESIAKRVARGEVLRAAPYLVVPCLVTDGAHHYGDERRDGAEREMFVVAMGAGVQNFLVALAGERLGSAWVSSTMFCRDVVRDVLGLPAGWDPMGAVAVGHAAEPPRERPERGASSFIEVR
>CP032698.1|AYG82471.1|5184954_5185911_-|2-phospho-L-lactate-transferase
MRIVVLAGGIGGARFLRGLKSAAPDADITVIGNTGDDIHLFGLKVCPDLDTVMYTLGGGINEEQGWGRTDESFTVKEELAAYGVGPEWFGLGDRDFATHIVRTQMLGAGYPLSAVTEALCARWQPGVRLLPMSDDRVETHVAIDVDGERRAVHFQEYWVKLRASVEAQAVVPVGAEQAKPAPGVLEAIAAADVILFPPSNPVVSVGTILAVPGIREAIAEAGVPVVGLSPIVGDAPVRGMADKVLAAVGVESTAAAVAEHYGSGLLDGWLVDTVDAASTARVEEAGIRCRAVPLMMTDLDATAAMAREALTLAEEVRA
>CP032698.1|AYG82472.1|5185955_5186498_-|Cysteine-dioxygenase
MNSSHSDLQIAGDILEVQHLLQPAREHPATVAEFAGLARSIAADRSQWAHLVQYDAVSRWYHRLRTVPQALGSARAGEAPIGYEVWLLSWVPGQGSGAHDHGASSGILTVLDGELTEHTERGVRSLAAGSQRVFAPGYAHDVVNDSLEPAVSLHVYYPGLTDMPMHPAQSPPATQDAVPA
>CP032698.1|AYG82473.1|5187204_5187468_+|Transcriptional-regulator-WhiB
MTELFQELLVDEAEEELGWQERALCAQTDPESFFPEKGGSTREAKKVCLACEVRSECLEYALANDERFGIWGGLSERERRRLKKAAV
>CP032698.1|AYG82474.1|5187726_5191533_+|N-acetylglucosaminyl-diphospho-decaprenol-L-rhamnosyltransferase
MSVHSQSTAPYEAATTPEFPRHVVTAVLVSHDGARWLPDVLAGLLGQERPVQNAYAADTGSADDSARLITEALGDERVLHLARRTGFGAAVEEAARTAPVLGPEELAYLKRPSGWDPVSRTWRDDSYDLPELPHGEPVQWLWLLHDDCAPEPDALAELLRVADSNPRAAIVGPKLRGWYDRKQLLEVGVSIAHSGRRWTGLDRREQDQGQHDQVRPVLSVSSAGMLIRRDVWQELGGFDRRLPLMRDDVDLCWRAHAAGHTVLVAPDAAVRHAEAAARERRTVDCAGRSVVNPHRVDKAGAVYTMLVNSRPALLPYVFLRIVVGTVLRTVAYLVGKVPGQAVDEVMGLFGTLLRPGRILAGRKRRGKSGVEAGELRPLFPPPGATIRATVESVAGSLGAGTEDTGGSRHGAVESGPGGDDADFLEIEQFARLKKIARKPAPVLFALLLVVSLVACRNLLGGGTLMGGALLPAPDHIGSLWSRYADAWHPIGAGGTQTAPPYLAILAVLSALCFGSTGLALTLLLVCSVPLAGLTAYFASRPLVASRQLRAWAAIAYAFLPAATGALAAGRLGTAVLAILLPPLARAGVSAAGFRGDGARGSWRATWTYALLLTVATAFTPVVWPLAVLLGLGVLALRRGDITAYGLRLLAAVGTPVLMLAPWSLTLLTGPSGFLKEAGLEYGDGSAGALDLLGASPGGPKTVGGLLLIGIVGAALAALLREERAFAIRTSWVVALTGFLFAALSNRSAWAGPATLVYGLALLAAAVLGAEYGRTRVAGHGFGWRQPVAALIALAAALGPVYSAAHWMIGGADGPLKRRDPVQVPAFVAEESGTRDQARTLVLGGTSPAKVAYTLVRGSGAQLGDAELAASGSGAARLGKVVSNLVAGSGADQSSQLSGFAVRYVLVRDGAPRAFARTLDSTPGLTRLSQLDGSALWRVDRQVARAVIVPAKGGESLPVAADPVDIHTAVPAGEAGRVLRIADTAAPGWSATLDGKALKKTTVDEWAQGFELPAGAGRLDVTYDAPFTHTVWIWTQAALALVLLVLALPGRRREIDDDLPEQEPTPAAAVPAQAVTGEGRRARRLRAQADAEAAPESGDPSSEQPARPAEVPQQPAYGEWDTAQYATTSPADTAEHDQQAQQGYDPYQQHYPGYQPYPEGQYPEGPYSDGQYTQASYPEQHYPDGSYPQVPGEEGQLGESQYGDGQYGDGQGGDGRYGDGQGGRPQGYDPYQQPGAQQPPPEGPYDPYGYGYPPEQPEQQPHRPDGSQQ
>CP032698.1|AYG82475.1|5191529_5193098_+|hypothetical-protein
MKRTTLSLAAAAVALAALTGFASLTAPAGSADTSATSPARLPVERSSLLCPAPSNSDLAQTTYTAFTPKGTAQGAPQGKPATATLTPAVPPPADSGTPSTDKAKDGKDKDGKDKKASAKTASDKPVISLKEPGKPTAATVSGADAPALTGSADGALAPGWAAQQTTQITGGVGRALLGLGCSAPDADFWFPGASTAKDRQDYVHLTNPDDTAAVADIELFGKDGPLKADVGEGITIPAKSSVPVLLSTLTGTVADDLTVHVTTRAGRVGAAVQATDAKAGADWLAASADAAPTQVLPGIPGDATDVRLIVHAQGADDADLKVKLASKGSSFTPVGLDSVHVKSGMTASFDLKNVTRGESGSLVLSPVSDGGTPVVAALRVVRGTGDKQEIAFIPATAPVGTRATVTDNRAKASTLALTAPGAKDATVKVTSSAGTEGGEPQSKTYTVKAGTTLAIDPQAPQGLKGSYALTIEPDPSSGPVYAARTLAVTQDGVPMFTVQTPADDKGTVAVPAASQDLSVLGK
>CP032698.1|AYG82476.1|5193193_5193595_-|hypothetical-protein
MRGPVAPPQVPLSVSRAETFRDLVLDSVERLERRWPQLAEVEFLISDVPFKDAPHADDDGEPEAWSDEAVPLGRAVAAGKDRPARILVYRRPVEIRTKNRDERALLVHEVVVEQVAELLGLAPESVDPRYGQE
>CP032698.1|AYG82477.1|5193954_5194374_+|hypothetical-protein
MESRRGPVKSAVPSNVVSPVRRCSRTACGRPAVATLTYVYADSTAVLGPLATYAEPHCYDLCAEHSERLTAPRGWEVVRLTDASAPSRPSGDDLEALANAVREAARPQERAAEAGGARAADPVEVGRRGHLRVLRSPES
>CP032698.1|AYG82478.1|5194554_5195916_+|Phosphomannomutase/phosphoglucomutase
MAVDLSQIVKAYDVRGVVPDQWDESLAELFGAAFVTVTQADAIVVGHDMRPSSPGLSAAFARGAAALGADVTLIGLCSTDQLYYASGALNLPGAMFTASHNPAQYNGIKMCRKGAAPVGQDTGLAEIRALVERWSEQGAPTVAAKAGTIVERETLTDYATHLKSLVDLSAIRPLKVVVDAGNGMGGHTVPTVFDGLPLDLVPMYFELDGTFPNHEANPLDPANIVDLQARVIAEGADLGLAFDGDADRCFVVDERGEPVSPSAITALVAARELARHPGGTVIHNLITSWSVPEVVRENGGTPVRTRVGHSFIKQEMAATGAIFGGEHSAHYYFADFWNADTGMLAALHVLAALGGQEGTLSALVAQYDRYAGSGEINSTVEDQKARAAAVRAAYEGQDGLTLDELDGLTVTAQDWWFNLRASNTEPLLRLNVEARDATTMAKVRDEVLALVRA

Crispr_ID: CP032698_64

• CRISPR_ID: CP032698_64
• CRISPR_location: 5342720-5342819
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_64

Consensus_repeat	Method
CGGCCCCTGGGGCTCCGCCCCAGACCCC	CRISPRCasFinder

spacers of CP032698_64

>64.1|5342748|44|CP032698|CRISPRCasFinder
ACGGGTTTTCCCACCCGCCCACCCGTGCGGCGGGTTGAAGGGTT

CRISPR arrays and Neighbor proteins around CP032698_64

CRISPR arrays

The CRISPR arrays of CP032698_64

>merge|CP032698|64|5342720-5342819|CRISPRCasFinder
CGGCCCCTGGGGCTCCGCCCCAGACCCCACGGGTTTTCCCACCCGCCCACCCGTGCGGCGGGTTGAAGGGTTCGGCCCCTGGGGCTGCGCCCCAGACCCC

>CP032698|64|47|5342720-5342819|CRISPRCasFinder
CGGCCCCTGGGGCTCCGCCCCAGACCCC	ACGGGTTTTCCCACCCGCCCACCCGTGCGGCGGGTTGAAGGGTT
CGGCCCCTGGGGCTGCGCCCCAGACCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82599.1|5347453_5347825_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82591.1|5336885_5337371_-|Regulatory-protein-AsnC	unknown	unknown	gnl|CDD|224439
CP032698.1|AYG82592.1|5337492_5338638_+|4-hydroxyphenylpyruvate-dioxygenase	unknown	unknown	gnl|CDD|273528
CP032698.1|AYG82588.1|5334034_5334913_-|Choline-transport-system-permease-protein-OpuBB	unknown	unknown	gnl|CDD|224095
CP032698.1|AYG82594.1|5340498_5341866_+|putative-FAD-linked-oxidoreductase	unknown	unknown	gnl|CDD|273050
CP032698.1|AYG82598.1|5346628_5347468_+|hypothetical-protein	unknown	unknown	gnl|CDD|377640
CP032698.1|AYG82587.1|5333051_5334035_-|Osmoprotectant-binding-protein-OsmX	unknown	unknown	gnl|CDD|270329
CP032698.1|AYG82595.1|5342053_5342542_-|Sporulation-specific-cell-division-protein-SsgB	unknown	unknown	gnl|CDD|377399
CP032698.1|AYG82602.1|5351124_5351712_-|Nicotinamidase/pyrazinamidase	unknown	unknown	gnl|CDD|238493
CP032698.1|AYG82604.1|5353387_5353693_+|ATP-dependent-Clp-protease-adapter-protein-ClpS	unknown	unknown	gnl|CDD|178809
CP032698.1|AYG82597.1|5344857_5346483_+|hypothetical-protein	unknown	unknown	gnl|CDD|377640
CP032698.1|AYG82605.1|5353692_5354274_+|hypothetical-protein	unknown	unknown	gnl|CDD|378185
CP032698.1|AYG82589.1|5334909_5336220_-|Glycine-betaine/carnitine/choline-transport-ATP-binding-protein-OpuCA	unknown	unknown	gnl|CDD|224050
CP032698.1|AYG82590.1|5336212_5336860_-|Choline-transport-system-permease-protein-OpuBB	unknown	unknown	gnl|CDD|224095
CP032698.1|AYG82603.1|5351822_5353151_-|Nicotinate-phosphoribosyltransferase-pncB1	unknown	unknown	gnl|CDD|236426
CP032698.1|AYG82601.1|5350794_5351094_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82593.1|5338756_5340400_-|Lipopolysaccharide-assembly-protein-B	unknown	unknown	gnl|CDD|276809
CP032698.1|AYG82586.1|5332286_5332913_-|hypothetical-protein	unknown	unknown	gnl|CDD|238042
CP032698.1|AYG82596.1|5343294_5344473_-|hypothetical-protein	unknown	unknown	gnl|CDD|379080
CP032698.1|AYG82600.1|5348244_5350635_+|Immune-inhibitor-A	unknown	unknown	gnl|CDD|368494

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82591.1|5336885_5337371_-|Regulatory-protein-AsnC	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	6.09946e-29
CP032698.1|AYG82592.1|5337492_5338638_+|4-hydroxyphenylpyruvate-dioxygenase	gnl|CDD|273528	TIGR01263, 4-hydroxyphenylpyruvate_dioxygenase, 4-hydroxyphenylpyruvate dioxygenase. This protein oxidizes 4-hydroxyphenylpyruvate, a tyrosine and phenylalanine catabolite, to homogentisate. Homogentisate can undergo a further non-enzymatic oxidation and polymerization into brown pigments that protect some bacterial species from light. A similar process occurs spontaneously in blood and is hemolytic (see . In some bacterial species, this enzyme has been studied as a hemolysin. [Energy metabolism, Amino acids and amines].	1.66483e-177
CP032698.1|AYG82588.1|5334034_5334913_-|Choline-transport-system-permease-protein-OpuBB	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	3.89441e-61
CP032698.1|AYG82594.1|5340498_5341866_+|putative-FAD-linked-oxidoreductase	gnl|CDD|273050	TIGR00387, Glycolate_oxidase_subunit_glcD., glycolate oxidase, subunit GlcD. This protein, the glycolate oxidase GlcD subunit, is similar in sequence to that of several D-lactate dehydrogenases, including that of E. coli. The glycolate oxidase has been found to have some D-lactate dehydrogenase activity. [Energy metabolism, Other].	5.77272e-140
CP032698.1|AYG82598.1|5346628_5347468_+|hypothetical-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	2.45742e-23
CP032698.1|AYG82587.1|5333051_5334035_-|Osmoprotectant-binding-protein-OsmX	gnl|CDD|270329	cd13611, PBP2_YehZ, Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein YehZ of Clostridium sticklandii is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. YehZ belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	9.88218e-146
CP032698.1|AYG82595.1|5342053_5342542_-|Sporulation-specific-cell-division-protein-SsgB	gnl|CDD|377399	pfam04686, SsgA, Streptomyces sporulation and cell division protein, SsgA. The precise function of SsgA is unknown. It has been found to be essential for spore formation, and to stimulate cell division.	7.31778e-44
CP032698.1|AYG82602.1|5351124_5351712_-|Nicotinamidase/pyrazinamidase	gnl|CDD|238493	cd01011, nicotinamidase, Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is also called pyrazinamidase, because in converts the tuberculosis drug pyrazinamide (PZA) into its active form pyrazinoic acid (POA).	5.5742e-67
CP032698.1|AYG82604.1|5353387_5353693_+|ATP-dependent-Clp-protease-adapter-protein-ClpS	gnl|CDD|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.41242e-39
CP032698.1|AYG82597.1|5344857_5346483_+|hypothetical-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	4.80089e-25
CP032698.1|AYG82605.1|5353692_5354274_+|hypothetical-protein	gnl|CDD|378185	pfam09438, DUF2017, Domain of unknown function (DUF2017). This is an alpha-helical domain found in gene neighborhoods that contain genes encoding ubiquitin, cysteine synthases and JAB peptidases.	1.29756e-58
CP032698.1|AYG82589.1|5334909_5336220_-|Glycine-betaine/carnitine/choline-transport-ATP-binding-protein-OpuCA	gnl|CDD|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	9.79214e-146
CP032698.1|AYG82590.1|5336212_5336860_-|Choline-transport-system-permease-protein-OpuBB	gnl|CDD|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	2.63689e-51
CP032698.1|AYG82603.1|5351822_5353151_-|Nicotinate-phosphoribosyltransferase-pncB1	gnl|CDD|236426	PRK09243, PRK09243, nicotinate phosphoribosyltransferase; Validated.	0
CP032698.1|AYG82593.1|5338756_5340400_-|Lipopolysaccharide-assembly-protein-B	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	5.73172e-08
CP032698.1|AYG82586.1|5332286_5332913_-|hypothetical-protein	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	6.41851e-12
CP032698.1|AYG82596.1|5343294_5344473_-|hypothetical-protein	gnl|CDD|379080	pfam13231, PMT_2, Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.	7.39306e-06
CP032698.1|AYG82600.1|5348244_5350635_+|Immune-inhibitor-A	gnl|CDD|368494	pfam05547, Peptidase_M6, Immune inhibitor A peptidase M6. The insect pathogenic Gram-positive Bacillus thuringiensis secretes immune inhibitor A, a metallopeptidase, which specifically cleaves host antibacterial proteins. A homolog of immune inhibitor A, PrtV, has been identified in the Gram-negative human pathogen Vibrio cholerae.	0

Protein sequences

>CP032698.1|AYG82595.1|5342053_5342542_-|Sporulation-specific-cell-division-protein-SsgB
MQTVVERELELKLVLSPERSIPVPARLTYRTDDPYAVHITFHVGSETPVHWTFARELLVEGVFRPCGHGDVRIWPTKVEGRNVVLMALSSPDGDALLEAPSAQVSAWLERTLRAVPPGSETERLGIDDGLAELLAPATGRGTDELWLRDPWPSDESRPEDGA
>CP032698.1|AYG82594.1|5340498_5341866_+|putative-FAD-linked-oxidoreductase
MDDLLVRLREHLPADAVITDPDITGGYAHDMASFCAAGTPAVVVLPRTVEQVQHVMRTATALRVPVVPQGARTGLSGAANASDGCIVLSLVKMDRILEVNPVDRVAVVEPGVINAVLSREVQKLGLYYPPDPSSWEMCTIGGNIGTASGGLCCVKYGVTAEYVLGLEVVLADGRLMSTGRRTAKGVAGYDLTRLFVGSEGSLGIVVKAVLALRPSPPPQLVLAAEFATAAAACDAVVRIMERGHTPSLLELMDRTTIQAVNRMAHMGLPDSTEALLLAAFDTPDPAADLAAVAELCTAAGATQVVPAEDAAESELLLQARRLSLTALETIKSATMIDDVCVPRSKLAAMIERTSAIAAKYDLTIGVCAHAGDGNTHPVVCFDAADEDESRRARESFDEIMALGLELGGTITGEHGVGVLKKEWLARELGPVGIEMQRAVKHAFDPLGLLNPGKLF
>CP032698.1|AYG82593.1|5338756_5340400_-|Lipopolysaccharide-assembly-protein-B
MEIAKTEQDADAARRAAWLSASAAARRTSPRSGPPKALKRAVRVALAAGVLIGGVVLIMPDDPGPKAPPPAPGPAARALTAVTGGAPASVADVTALITDRAAWVRTHPKDEASWAVLGSAYLERGVRGADSSFYPRAEWALRRSLEVRPKDNLDAEIGLAALANARHDYAAARTLAESVRARKADRWTLYPPLIEAYNGLGDAKGAAKAVERLLELRDGSAALTQAAEVYRAHGWREDASVALDEAVAHATSPVQKAASLVAAGDLAWERGEPEAALARYEAALRTDPGAHAALAGRARAGAALGKKADAQRDYLAAVAVLPRPEYLLELGELYESQGLDGDARTWFDKLQELAARDGSNGVDDALVLGRYEADHGSAHAAVDRLEAEWKAHPSPAVEDALGWAMYRAGESEEGLTHAKKATDSGVRSALFSYHQAVIERELGQSGAARRHLQDALRTNPYFSPVLAPKAKEALTALGEPPEGGPRDMYGHVAAAASGSGSGSGSGSGGESSASSDASSNQSGQSSQGARRPAKPRPAKPAKPSQRR
>CP032698.1|AYG82592.1|5337492_5338638_+|4-hydroxyphenylpyruvate-dioxygenase
MTETIDHTPETARQADPFPVKGMDAVVFAVGNAKQAAHYYSTAFGMKLVAYSGPENGSRETASYVLTSGAARFVFTSVIKATSERGRFLAEHVAEHGDGVVDLAIEVPDARAAYKYATEHGATGLQEPHEVSDEHGTVVLAAIATYGKTRHTLVERSGYEGPYLPGFVTAAPMVEPVEKRFFQAIDHCVGNVELGKMNDWVAFYNNVMGFTNMKEFVGDDIATEYSALMSKVVADGTLKVKFPLNEPAIAKKKSQIDEYLEFYGGPGVQHIALATNDIVASVRAMRAAGVQFLDTPDSYYDTLGEWAGETRVPVETLRELKILVDRDEDGYLLQIFTKPVQDRPTVFFEMIERHGSMGFGKGNFKALFEAIEREQELRGNL
>CP032698.1|AYG82591.1|5336885_5337371_-|Regulatory-protein-AsnC
MAIDHLDGRLIVLLAREPRIGVLEASRRLGVARGTVQARLDRLQSNGVIRGFGPDVDPAALGYPVTAFATLEIKQGQGADVRAHLASVPEVLELHTTTGHGDMLCRLVARSNADLQRVIDRVVGFDGIVRASTAIVMENPVPLRIIPLVEQAGQDSVPGGG
>CP032698.1|AYG82590.1|5336212_5336860_-|Choline-transport-system-permease-protein-OpuBB
MGFWDYLSSRHQQLLTDALQHASAVFQCMVIATVLGILIGVVTYRSGWAAALAITSTSTVLTIPSLAMIGLLIPLVGLGVAPTVVTLTLYGLLPIVRNAIVGLRGVDPSLVDAAKGIGMSRPARLLRVELPLAWPPILTGIRVSTQMLMGIAAIAAYASGPGLGNEIFRGIASLGSANAINQVLAGTLGIVVLALLFDAAYVLIGRLTIPRGIRV
>CP032698.1|AYG82589.1|5334909_5336220_-|Glycine-betaine/carnitine/choline-transport-ATP-binding-protein-OpuCA
MSERSESERSESERSESERSESAGASTAKASTSGASIQLEELTKRYPGSAEPAVDSVTMEIKAGETVVFVGPSGCGKSTTLKMINRLIEPTSGRIRIDDEDVTDIDPVKLRRKVGYAIQSSGLFPHMTVAENIALVPKMVGWSKARVKDRVEEMLDLVGLDPREFHGRYPRQLSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRDHLQDELIRLQHELHKTIVFVTHDFDEAIKLGDRIAVLRERSHIAQFDTPEAILTNPADDFVSGFVGAGAALKRLNLTRVRDVEMAEFPTVTVDDPPQSIFNKLRSGPHNELLMLDRRNRPYKWLRRGDLMRAKGSLARAGQMVHDTVTRGATLHDALEAVLIDSGGRVAVTGRRGEYIGVVDMETLMNSVHELLEADRLAAIEHQHDLEELRHHQTEQELEGGATQP
>CP032698.1|AYG82588.1|5334034_5334913_-|Choline-transport-system-permease-protein-OpuBB
MTPRSPAPAERPPGEHEVGGHAFRDELPGPLDEPEPEHETGPAPDRPARRITWRKLAFLPVVLAVVLVITYLWITHVHLDTIAKNSLNNGNVQLRLWQHVKLTAISTFWVLLIAIPLGIALTRRGVSRAAPLVTAIANIGQATPAIGLLALLVIWLGIGPGTAIVGMVIYAVLPVLSNTVAGLRAIDPQLVEAARGIGMSAPGTLGKVELPLAVPLILAGVRTALVLNVGTATLATFGGGGGLGDLITSGIQTQRMPVLVLGSILTVALALLVDWLASLAEIALTPRGLEVE
>CP032698.1|AYG82587.1|5333051_5334035_-|Osmoprotectant-binding-protein-OsmX
MRHPRTALLAASGSLALLAVVSGCGLKSGSPLVDDVLPGSIGKGLPLKGASLTVTSKNFSENIVLGQMVGLVFKAAGAEVLDRTNLPGSISAREAIAKGDADAMYDYTGTAWITYLGNSKPITDPGAQWRAVRDADLKNGVTWLPQSTLNNTYSLGISQANNAKYHLKTLSDVAALAKKDPSAVTICVENEFASREDGLPGMEKAYGMTVPASNIQKMDAGIIYTQVSKSNSCLLGEVFTTDGRIQAMNLATVQDDKHFFPNYNAAPVVHSRTYEKYPAIAALLDPLSAKLTTGIARQLNAKVDVDGQDPHDVALEWLVREGFIRKG
>CP032698.1|AYG82586.1|5332286_5332913_-|hypothetical-protein
MPENKRSAAPPPENPAGERILDARSLRGLAHPLRIRILKSLRHDGPATASQLGDRLGESSGATSYHLRQLATHGFVEDDPARGKGRERWWKAVHNGTSFADDLHTSSDPEVRGAANLFLHEIAGIHTQELSTWLATMHDWPEPWSTSGDLSDFTLNLSPAQLHELNEKLHAVVESYRTLSPGPGAPSDAEAAQVRVHLHSFPRGNPSR
>CP032698.1|AYG82596.1|5343294_5344473_-|hypothetical-protein
MSVGLGPTGRGERAALSSAALSSAAPVARRAWSAVGAFAAIRALGLLALVLWSRANDKDAHALLSARWDSLWYVRVVESGYDFTLTAPDGRVLSDLAFFPLLPWLEQALAAVTPLGPGDAGLLVSAVAGPLAAWALYLTGRHLHGHRAGLLLAAVWAAVPVGIVQSMAYSEALFTALAAWALYAVLRRRWVEAGLLASLAGLTRPVGLAVAAALWAGAVVEARRTRRVDARLLTGAVLAPLGAAGYVLWVGARRGSVFGYLHVQAEWGNGFDGGLAYGKFIVDHLGGWPVVLAGLGMIAGTALALWAYGACVRGGQPLPLLVYTGIVMALALCSSGYFGSKPRLLLPAFPLLLPVAVALSRMRGVGAVGVVGALSVASAVYGATWLNGSGPP
>CP032698.1|AYG82597.1|5344857_5346483_+|hypothetical-protein
MATVPSDSDGSGAREGYYPDPSIPGYVRYWNGVSWVPGTSRPAPAAGEAPPTPPLGATPAPAPSLAAAPPVTAALAEETGPVFLDEPEASPASAQGSAAPQPAWHADAAHQSGFGGDQDRRVSWGQSVDGRALPESADPRQLPDPRRLPDPRRAEPARPTPTGPSTGPSTGPSTGPSTGPSTGPSTGPSTGPSTGSSTGPFGDPARPAGTVPHQSPQQSAQFAQSANAAQSANAAHPAPSAHSANSARAARPAQPIQSAPPIQPAAPFAGTVPPTAVEPAPVRPQLPTPADPVVAAPTSPAYSAPATPQPQPAQPAQPGPVEPHPGLPGSPMTDGPGGGAASWAQQVHRLAQPDAQAQEPVVPWKPPVDDPFLRAAREQASARPAGLVRRLIARLVDTALLGALVAGLAVPLLARVADHVQQKIDAAKLSGQTVTVYLLDGTTAGLLGIVLGAFLLLGLLYEALPTAKWGRTLGKRLCGVQVRGIESYEPPTFGQAVRRWLVHGVLGLLVIGVVNVAWCLFDRPWRQCWHDKAAHTFVAQG
>CP032698.1|AYG82598.1|5346628_5347468_+|hypothetical-protein
MSTDQPPPGQPPEDDPFLKKPSEPPRSGSPYGGTQPPPGRPPGDSPYGAGPPSGGDGPYGAPPPPSGAGGPYGAPPPRSGAGGPYGGPPPPGGGSPYGSAPPPPSDPYGGQYGGVDPLAGMPPLADFGKRFLARFIDFLIIAIPLGLIEWATSNRVVISTSDNGDSGTEVISKAYSGSGLLWLLITLVVYIGYDTLMVSKSGQTLGKKLLGLRVAMLNDGSVPTTNAALARAAVLWAPFVLCCYCLWDIILGITIVTDKPYRQGWHDKAGKTVVVSTPQ
>CP032698.1|AYG82599.1|5347453_5347825_-|hypothetical-protein
MPRPTAAQLSYGSATVVFSTVAMLLLSRTESGVGVAVIVLAALLLGLLVAVTVPMPLARRTRADAHANADGRTVPAAGAAPVNRAAVVETSAAGAAASPSGQWGSVPAPRERRASTRQHSLRS
>CP032698.1|AYG82600.1|5348244_5350635_+|Immune-inhibitor-A
MTSSRRAARAAAVLVALATAGATGSAYATAQADSKAPAPVQRQDPSRANGQEHNLKGPFSDQQAQQRQAALEQVISGKKKVEKRGASDVVKLSDKKYVELGREKTDKIFTILVEFGDQVDNTTMYDPDGPDGPKPPQPKYGGTPGPAHNQIAKPDRSKDNSTAWQADYNQKHFQDLYFGTGKNVNSLKTYYEKTSSGRYSVDGQVTDWVKIPYNEARYGSNYCGQTNCANVWDTVRDGVNAWVADQKAKGQTDAQIKATLGQYDQWDRNDYNNNGNFNEPDGYIDHFQIVHAGEDESAGGGAQATNALWAHRWYAYGTDAGKTGPANNKAGGTQIGDTGMWVGDYTMQPENGGLGVFAHEYGHDLGLPDLYDTTNTAENSVGFWSLMSAGSWLGTGKDSIGDLPGDMTAWDKLQLGWLDYASVKAGSKITAKLGVSEYNTKNNQALVVELPKKEVTTTVVKPVEGSKQWWSGMGDNLNNTLTRSVDLTGKSKASLDLSGWWDIEKDYDFLYTEVSTDDGASWNAIDGTADGKAITRDSSDKPALTDASGAYKKLSYPLDQYAGHKIQLRFRYQTDGGAGGKGFTADAISVTADGTAVVTDGAEAGDNGWAAKNFTRIGESFTNDYPQYYLAENRQYVSYDTTLKVGPYNFGFSTTRPSWVEHYPYQRGLLIWLWDTSQKDNNVSAHPGQGLILPVDAHAKPLKWADGTLLRNKIQPFDAPFSQYRTDAFTLHKADVATKIKSQAGVPVFDDHQGTYWYAENPTGSVKVPDTKTRISIVDQPWNGQTITVKVGTSTK
>CP032698.1|AYG82601.1|5350794_5351094_+|hypothetical-protein
MPGGGYCKLPGGSVVVALTLPNPAAPGSDVRVLVHAVNRARALTRLRNLGLRAVYLRGQTEPPTLDEITAVLHHPDGLLWRTAPETTEELWHPIRALLR
>CP032698.1|AYG82602.1|5351124_5351712_-|Nicotinamidase/pyrazinamidase
MHRALIVVDVQNDFCEGGSLAVAGGADVAAAITDLVGQAAGSAYRHVVATRDHHIDPGTHFSATPDFEHSWPPHCVAGTEGVGFHPNFAPAVACGAVDAVFDKGAHAAAYSGFEGFDENGVALAEWLRARQVAEVDVVGIATDHCVRATALDAVRAGFVTTVLLDLTAGVAERTTSLALEEMRTAGVGLSGKPVV
>CP032698.1|AYG82603.1|5351822_5353151_-|Nicotinate-phosphoribosyltransferase-pncB1
MNAADLGLPVDVPSTALFTDQYEFTMVQAALKAGTAGRRSVFEAFTRRLPEGRRYGVVGGIGRVLDAVENFRFDAGVLGFLHDHSIVDEPTLRWLSSYRFSGDIWGYPEGEVYFPGSPILRVEGSFAECVLLETVILSILNHDSAIAAAASRMSTAAGGRPLIEMGARRTHELSAVASSRAAYVGGFSSTSDLAAGFRYGIPTVGTSAHAFTLLHDSERDAFRAQVDSLGRGTTLLVDTYDVAEAVRTAVEIAGPELGAVRIDSGDLLLVAHRVRQQLDDLGATATKIVVTSDLDEYAIASLAAAPVDAYGVGTQLVTGSGHPTCSMVYKLVARAQSADPKAPLISVAKKSLGAKSSVGGRKWAARRSDAYGIAEAEVIGTGAVPAELVERQLLVELVKGGTVVAREPLDAARARHIDALAALPMSAGQLSRGEPVIPTEYV
>CP032698.1|AYG82604.1|5353387_5353693_+|ATP-dependent-Clp-protease-adapter-protein-ClpS
MSVAPVEIERPESAESSRPVAEPDVPWVTLVHNDPVNLMSYVQYVFQSYFGYSKDKAHKLMLDVHHKGRAVVSSGSREEMERDVQAMHGYGLWATLTQDRG
>CP032698.1|AYG82605.1|5353692_5354274_+|hypothetical-protein
MAGHFEPLPGGGAAVALDEVEIAILRSLAVQLLELIGPGRAPAEDEDPLAALFAEGPSEPPADPALARLFPEAYASEESDELRAKSAEFRRFTENDLRARKRDDALAVVHGLDALSPRGDGGAVLKLAADDSRHWLGALNDLRLTIATRLDITDEDESGELYRLPDDDPRKPMVMAYLWLGVLQETLIDTLMS

Crispr_ID: CP032698_65

• CRISPR_ID: CP032698_65
• CRISPR_location: 5406002-5406082
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_65

Consensus_repeat	Method
TTCCGCGCAGTTCCCCGCGCCCCTA	CRISPRCasFinder

spacers of CP032698_65

>65.1|5406027|31|CP032698|CRISPRCasFinder
AACCCCCTCGATCCTGCGGGCCGTGGTCGCT

CRISPR arrays and Neighbor proteins around CP032698_65

CRISPR arrays

The CRISPR arrays of CP032698_65

>merge|CP032698|65|5406002-5406082|CRISPRCasFinder
TTCCGCGCAGTTCCCCGCGCCCCTAAACCCCCTCGATCCTGCGGGCCGTGGTCGCTTCTCGCGCAGTTCCCCGCGCCCCTA

>CP032698|65|48|5406002-5406082|CRISPRCasFinder
TTCCGCGCAGTTCCCCGCGCCCCTA	AACCCCCTCGATCCTGCGGGCCGTGGTCGCT
TCTCGCGCAGTTCCCCGCGCCCCTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82650.1|5397051_5397375_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82652.1|5398557_5399415_+|Ureidoglycolate-lyase	unknown	unknown	gnl|CDD|223257
CP032698.1|AYG82659.1|5406475_5407606_+|D-amino-acid-dehydrogenase	unknown	unknown	gnl|CDD|132407
CP032698.1|AYG82657.1|5404346_5405162_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82663.1|5410240_5411038_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnV	unknown	unknown	gnl|CDD|132299
CP032698.1|AYG82655.1|5401819_5402905_-|scyllo-inositol-2-dehydrogenase-(NADP(+))	unknown	unknown	gnl|CDD|183212
CP032698.1|AYG82666.1|5413334_5413901_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82660.1|5407620_5408346_+|Phosphonoacetaldehyde-hydrolase	unknown	unknown	gnl|CDD|274534
CP032698.1|AYG82658.1|5405655_5405994_+|HTH-type-transcriptional-repressor-DasR	unknown	unknown	gnl|CDD|369472
CP032698.1|AYG82662.1|5409414_5410254_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnU	unknown	unknown	gnl|CDD|237888
CP032698.1|AYG82653.1|5399790_5401206_+|hypothetical-protein	unknown	unknown	gnl|CDD|275059
CP032698.1|AYG82664.1|5411173_5412250_+|Putative-2-aminoethylphosphonate-binding-periplasmic-protein	unknown	unknown	gnl|CDD|237887
CP032698.1|AYG82668.1|5414741_5415971_+|Endoglucanase-A	unknown	unknown	gnl|CDD|376532
CP032698.1|AYG82654.1|5401229_5401823_-|hypothetical-protein	unknown	unknown	gnl|CDD|179430
CP032698.1|AYG82651.1|5397668_5398424_+|Membrane-protein-insertase-YidC	unknown	unknown	gnl|CDD|274665
CP032698.1|AYG82656.1|5402973_5404074_+|N-acetylglucosamine-repressor	unknown	unknown	gnl|CDD|224851
CP032698.1|AYG82661.1|5408342_5409422_+|Putative-2-aminoethylphosphonate-import-ATP-binding-protein-PhnT	unknown	unknown	gnl|CDD|226361
CP032698.1|AYG82667.1|5413902_5414586_+|hypothetical-protein	unknown	unknown	gnl|CDD|320678
CP032698.1|AYG82665.1|5412453_5413233_+|Ribonucleotide-monophosphatase-NagD	unknown	unknown	gnl|CDD|319832
CP032698.1|AYG82649.1|5396471_5397005_+|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|224647

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82652.1|5398557_5399415_+|Ureidoglycolate-lyase	gnl|CDD|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	6.76182e-91
CP032698.1|AYG82659.1|5406475_5407606_+|D-amino-acid-dehydrogenase	gnl|CDD|132407	TIGR03364, putative_secreted_oxidoreductase, FAD dependent oxidoreductase TIGR03364. This clade of FAD dependent oxidoreductases (members of the pfam01266 family) is syntenically associated with a family of proposed phosphonatase-like enzymes (TIGR03351) and is also found (less frequently) in association with phosphonate transporter components. A likely role for this enzyme involves the oxidative deamination of an aminophosphonate differring slightly from 2-aminoethylphosphonate, possibly 1-hydroxy-2-aminoethylphosphonate (see the comments for TIGR03351). Many members of the larger FAD dependent oxidoreductase family act as amino acid oxidative deaminases.	3.16931e-108
CP032698.1|AYG82663.1|5410240_5411038_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnV	gnl|CDD|132299	TIGR03255, PhnV, 2-aminoethylphosphonate ABC transport system, membrane component PhnV. This membrane component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.	4.61015e-54
CP032698.1|AYG82661.1|5408342_5409422_+|Putative-2-aminoethylphosphonate-import-ATP-binding-protein-PhnT	gnl|CDD|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.37997e-138
CP032698.1|AYG82660.1|5407620_5408346_+|Phosphonoacetaldehyde-hydrolase	gnl|CDD|274534	TIGR03351, PhnX-like, phosphonatase-like hydrolase. This clade of sequences are the closest homologs to the PhnX enzyme, phosphonoacetaldehyde (Pald) hydrolase (phosphonatase, TIGR01422). This phosphonatase-like enzyme and PhnX itself are members of the haloacid dehalogenase (HAD) superfamily (pfam00702) having a a number of distinctive features that set them apart from typical HAD enzymes. The typical HAD N-terminal motif DxDx(T/V) here is DxAGT and the usual conserved lysine prior to the C-terminal motif is instead an arginine. Also distinctive of phosphonatase, and particular to its bi-catalytic mechanism is a conserved lysine in the variable "cap" domain. This lysine forms a Schiff base with the aldehyde of phosphonoacetaldehyde, providing, through the resulting positive charge, a polarization of the C-P bond necesary for cleavage as well as a route to the initial product of cleavage, an ene-amine. The conservation of these elements in this phosphonatase-like enzyme suggests that the substrate is also, like Pald, a 2-oxo-ethylphosphonate. Despite this, the genomic context of members of this family are quite distinct from PhnX, which is almost invariably associated with the 2-aminoethylphosphonate transaminase PhnW (TIGR02326), the source of the substrate Pald. Members of this clade are never associated with PhnW, but rather associate with families of FAD-dependent oxidoreductases related to deaminating amino acid oxidases (pfam01266) as well as zinc-dependent dehydrogenases (pfam00107). Notably, family members from Arthrobacter aurescens TC1 and Nocardia farcinica IFM 10152 are adjacent to the PhnCDE ABC cassette phosphonates transporter (GenProp0236) typically found in association with the phosphonates C-P lyase system (GenProp0232). These observations suggest two possibilities. First, the substrate for this enzyme family is also Pald, the non-association with PhnW not withstanding. Alternatively, the substrate is something very closely related such as hydroxyphosphonoacetaldehyde (Hpald). Hpald could come from oxidative deamination of 1-hydroxy-2-aminoethylphosphonate (HAEP) by the associated oxidase. HAEP would not be a substrate for PhnW due to its high specificity for AEP. HAEP has been shown to be a constituent of the sphingophosphonolipid of Bacteriovorax stolpii, and presumably has other natural sources. If Hpald is the substrate, the product would be glycoaldehyde (hydroxyacetaldehyde), and the associated alcohol dehydrogenase may serve to convert this to glycol.	8.30472e-59
CP032698.1|AYG82658.1|5405655_5405994_+|HTH-type-transcriptional-repressor-DasR	gnl|CDD|369472	pfam07702, UTRA, UTRA domain. The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to pfam04345. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.	4.75763e-21
CP032698.1|AYG82662.1|5409414_5410254_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnU	gnl|CDD|237888	PRK15050, PRK15050, 2-aminoethylphosphonate transport system permease PhnU; Provisional.	2.25908e-122
CP032698.1|AYG82653.1|5399790_5401206_+|hypothetical-protein	gnl|CDD|275059	TIGR04215, conserved_hypothetical_protein, choice-of-anchor A domain. This domain may occur as essentially the full length of a protein, except for an N-terminal sequence and a C-terminal protein-sorting signal such as PEP-CTERM or LPXTG. Most often, the putative surface protein is longer and contains repetitive sequence regions. This is one of very few domains for which both anchoring domains occur, and designated choice-of-anchor A domain. The best characterized member is Bacillus anthracis protein BA0871, a collagen-binding protein with five CNA-family protein B-type repeats toward the C-terminus and an LPXTG cell wall attachment motif.	2.06521e-44
CP032698.1|AYG82664.1|5411173_5412250_+|Putative-2-aminoethylphosphonate-binding-periplasmic-protein	gnl|CDD|237887	PRK15046, PRK15046, 2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional.	1.08133e-168
CP032698.1|AYG82668.1|5414741_5415971_+|Endoglucanase-A	gnl|CDD|376532	pfam01341, Glyco_hydro_6, Glycosyl hydrolases family 6.	3.87146e-80
CP032698.1|AYG82654.1|5401229_5401823_-|hypothetical-protein	gnl|CDD|179430	PRK02487, PRK02487, heme-degrading domain-containing protein.	5.56091e-69
CP032698.1|AYG82651.1|5397668_5398424_+|Membrane-protein-insertase-YidC	gnl|CDD|274665	TIGR03592, yidC_oxa1_cterm, membrane protein insertase, YidC/Oxa1 family, C-terminal domain. This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking].	3.25755e-34
CP032698.1|AYG82656.1|5402973_5404074_+|N-acetylglucosamine-repressor	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	3.79293e-41
CP032698.1|AYG82655.1|5401819_5402905_-|scyllo-inositol-2-dehydrogenase-(NADP(+))	gnl|CDD|183212	PRK11579, PRK11579, putative oxidoreductase; Provisional.	2.24859e-100
CP032698.1|AYG82667.1|5413902_5414586_+|hypothetical-protein	gnl|CDD|320678	cd05829, Sortase_F, Sortase domain found in the class F family of sortases. Class F sortases are mainly present in Actinobacteria, Chlorobacteria and Firmicutes. Their functions are largely unknown.	1.49661e-51
CP032698.1|AYG82665.1|5412453_5413233_+|Ribonucleotide-monophosphatase-NagD	gnl|CDD|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.74357e-130
CP032698.1|AYG82649.1|5396471_5397005_+|putative-HTH-type-transcriptional-regulator	gnl|CDD|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	2.47727e-23

Protein sequences

>CP032698.1|AYG82658.1|5405655_5405994_+|HTH-type-transcriptional-repressor-DasR
MERVLLADDERMGLESTYAAVSRMPDLDTEFEPDSSFYAYLRDRLGLALGDVDERIETVLATPREALLIGTPPALPMLLIHRVSRDAAGVPLERVRTLYRGDRFSFTTHLAR
>CP032698.1|AYG82657.1|5404346_5405162_+|hypothetical-protein
MRLRLRPRLRPRTALVTAVVAATIAPLAGVAAADDGGLPPGRHDLAPRKPVVAAMPVDPPLSAKLPLCASRTGTAFPLDTKIHGGPAEYHPGDESQSWSLDLTNTSRETCDAIHPVLVLVDRDRTLKNSQLRMDFDDPATGRKHPVTFLGTDQDEHIGVFDDGFPGFTIGAGKTLTVPVRLGFGADAVADRVTANAAIVQRRGSNGQWVGESGDYRFAIVPEGDLLERIDTELAETGRGSALAGLALTAAVLLLAGAALVVAARGPRTRRR
>CP032698.1|AYG82656.1|5402973_5404074_+|N-acetylglucosamine-repressor
MNTSTTGANLPALRNHNAALVLDLLRAAGEHGISRLELAERTGLTPQAVSKITGRLRDEGTATEAGRRASTGGKPRTVLKLVPSAAHAIGLHLDRDELTAVLVDLAGTLVGARTVPLDLGAKPSDVVETAAAEAEALTGGRRVLGVGVAMPGPLDHDSGVLHRVTGFPHWNGFPLRDALADRLGRKVVLDKDTNAAALGLALRAGGRAGSFAYIHLGSGLGAGLVLGGAVHRGARTGAGEFGHQTILLGGPVCGCGGRGCIEALCLASVARGDIAAAARFLGVGAANLVGLLDIDAILLGGRTVTADQDTFVRGVGAVVEERARRGGAPAIPVGPAAGGPHAVAEGAAQLVLVPVFGRANVAYPQP
>CP032698.1|AYG82655.1|5401819_5402905_-|scyllo-inositol-2-dehydrogenase-(NADP(+))
MNAPQTEGLRVGLVGYGLAGSVFHAPLIAATEGLALDTVVTSNPERRAQARAEHGAALRFADSPEELYDAGLDLVVIASPNKTHVSIATGALKAGLPVVVDKPLAGTAAEARDLASLAEERGLLLSVFQNRRWDNDFLTLQRLIADGELGEIQRFESRFERWRPQPKGGWRESGDPSEIGGLLYDLGSHVVDQALVLFGPALRVYAEADVRRPGAQADDDTFIAITHANGVRSHLYVSATTAQLGPRFRVLGSSAGYVKYGLDPQEAALREGERPSAGKPWGVEPESLWGRIGSGESPLTGGGDPVKTAPGDYPAYYAAIAKALREGGEPPVTAHEAAAALDVLEAARRSAREGVTVELAL
>CP032698.1|AYG82654.1|5401229_5401823_-|hypothetical-protein
MRAHATTAKPQTAEGASVSGNRAEGAPATDATPAGGPPAADPVAALEAERERLVLSRFSYEDAWQLGLLLRELAVERAAPVVIDVRHGARQVFRCALPGSSADNDAWIDRKRRVAERYAAPSFLVGARFRAKGTTFEDASRLDPNSYAAHGGSYPVSVEGVGIVGTVTVSGLPQAEDHALVVEALTRWVNTRDHQGG
>CP032698.1|AYG82653.1|5399790_5401206_+|hypothetical-protein
MRNTPGIRKRAATASAVVVGAAVVVGAMGTFGFADPLPDGLGPCKGSHCPVVPYPDPNNGSLAGRDNNINVFVGGDFLVRQAAAEAEGKVVVLGKFDQHKATGVSQVYNVGVAGVGSRVPPDNGTDFLTTGQDVVVAAGQRLLAEEGSVFGVVRHGGTLTGTVRPRTVHDPDAAAPYARLKPNLAAASHCYAYVDGKPRHATGTARNNGNETLFTGDGKSPLQVFNVDFDLTGPSGRAQGFLFTGIPAGATVLVNLTGDVREINTYMGMLPAALRDRLLWNFPDAETVRLRGSGQFSGSVLVGNGDSTTTVTLPGLNGRFFTVGSLVHTSVVGGGGGQEIHAYPFNGDLPGCRGEEPTPTPPTPEPPTPTPDPPTPEPPTPEPPTPTPEPPTPSPTDSEGTNTGGASGGNDGGSDSGGHGSDGGGELPDTGTPSGTTMVIGGIAVTLVAAGGATLAVTRKPKGLRRLRKGH
>CP032698.1|AYG82652.1|5398557_5399415_+|Ureidoglycolate-lyase
MKLLRVGDAGQERPALLDADGTLRDLSGLVADIDGALLADETALDRIRAAADTGALPALDDPGVRVGPPVGRIGKVVCIGLNYHDHAEETGAAVPAEPVVFFKAADTVVGPHDTVLVPRRSVKTDWEVELAVVIGRTARYVSDDENPLAYVAGYAVSHDVSEREFQIERGGTWDKGKNCETFNPLGPWLVTRDEVPDPQALSLRLWVNGSLKQDGTTAQQIFSVAEVVRYVSQFMTLYPGDVINTGTPAGVAMGQPEPKPYLRAGDVVELEVAGLGRQRQGFKDA
>CP032698.1|AYG82651.1|5397668_5398424_+|Membrane-protein-insertase-YidC
MFTSLFSAFASLTEHLAALLEPAFHGASTAAAIVLFTALVRLAVHPLSRQAARGQKAQATLRPQLAALREKHGKDSKALQKAIMELHAAEKVSPFSGCLPSLLQMPAFFLLYHLFSSAEIGGRANALLDHTLLRAPLGGCWTDALAHGGAFGPQGLVYVVLFAVVAAVASFNYRRMKRQMAANPVAAPGGQEAVPGMAAMNKFMPLLSFATLFTVAVVPLAAALYVVTSTTWTAVERAFLYKDTLPALAAV
>CP032698.1|AYG82650.1|5397051_5397375_+|hypothetical-protein
MSGVIARCARLARPLFGLLLFLLAQAVLIEGGMLSAAVALAATAAAGSALAVCATLASRAVPQVPRTRVRTAIRDRERRTAFLAQRDPDASGRPRPRAPGALVPTAA
>CP032698.1|AYG82649.1|5396471_5397005_+|putative-HTH-type-transcriptional-regulator
MALRKDYDYAAQECSVARALEIIGERWTLLVVRDALYGVRRYNDFLVHLKIPRAVLAARLQTLTEAGVLEKRRYQEAPTREEYVPTELGRALWPTVRALGVWGRAVNPDARPMRTFHHAECGTELGTYGECRACGRVVDPEDVEMRPGVGLGPGEDPVSRALRAPRRLLQPLFERRV
>CP032698.1|AYG82659.1|5406475_5407606_+|D-amino-acid-dehydrogenase
MRVIVVGAGVVGTMHAWHAVHRGHEVVHIERETQPRGASLRNFGQIWVSGRAGGEELETALRARALWEGIGERVPRLGFRPNGSLTPLRTELEVAVAEAAVARADADARGYRIVTAAGARALNPALRGDLTAALWCERDAAVEPRTAQLALQEALLASGRYTFLGGREVRDVTEGPSGPAVRDDHGDTHRGDGVVLCTGAWLGGLMRELAPDLPVRRVRLQMMQTAPLGEPLTTSLADADSFRYYPAYASEALDALNAGQAQDPLAAAHRMQLLMVQRADGGLTIGDTHEYEHPFAFDVLEEPYDHLVRVVESFLGRPLPRIERRWAGVYAQCTDTSRVVHREQVRDGVWLVTGPGGRGMTCSPAIAEKTANELDW
>CP032698.1|AYG82660.1|5407620_5408346_+|Phosphonoacetaldehyde-hydrolase
MNASGVNASEVSTYGLVVLDMAGTTVADGGLVERAFARAAARLGVEPGSAEHATMLDHVRATMGESKISVFRHLFGDETKAQAANAAFEEAYGSLVDGGLLAPVPGAREAVERLRFEGRTVVLSTGFARATQDAILAALGWRDLVPLTLCPADAGGRGRPYPDMVLSAFLRTGAVDSVRRVAVAGDTSYDMLSGVRAGAGVVAGVLTGAHDEPALLSAGATHVLVSVAELPDVIAELEANQ
>CP032698.1|AYG82661.1|5408342_5409422_+|Putative-2-aminoethylphosphonate-import-ATP-binding-protein-PhnT
MSGSASPGAPRGGIRFDGVTVAYQHAVVLDSLDLSVEPGEVMALLGPSGSGKTTALRAVAGFVQPVRGRIFLGDRDVTRLPPHRRGIGMVVQQYALFPHMRVEDNVAFGLKAHRVPKAGIAARVTEALAMTGMDGYAKRYPRELSGGQQQRVAIARALAIRPGVLLLDEPLSALDAQLRSGMLAELARLHRELPDVSILYVTHDQVEALTLADRIAVMDKARLQDCGTPQDLYRRPRTEFTASFVGNANLLPVRVGSGSVLFGDTELSVATDEAAWGSSATLCVRPHLVGLGAGPNALRGTVAEVQWRGSTHRLYVDVAGHRVKADVRELKVTPAIGDEVTLHFAREDAVLLAAGVSHG
>CP032698.1|AYG82662.1|5409414_5410254_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnU
MASPARPAPAALWALVPVAVLTAVFLYPLALVVRQSLSPDTGGTSLQAYTDVFASAAFRDALGTTVWLAVGASAGCVVLGFVLALVIAFVPFPGGKVVARFIDVFLSFPSFLITLALLFVYGTVGMANGLWSDVTGTTGTGPFQFLTTPWGVLLAEITYFTPFVMRPLLAAFSQLDTIQLEVASSLGARPARIVRRVILPEALPALAAGGSLVLVMCLNEFGIVLFTGAKGVTTLPMLVYGKAILESDYPAACVVAVVNIVISVGLYGLYRVVSRRAGA
>CP032698.1|AYG82663.1|5410240_5411038_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnV
MLVHSRGGRWAARTVFFVLFLPVFALPLLVVVAASFATNWSGALPSGFTTGHYAAATTGESLQALTTSLVTALTASVLALVVGTWAALAAAALGTGGRRFMDALFVLPVAVPSVVVGLAVLVAFSEPPVLLNGTRQIVILAHTVLVTAFAYQSVSAAVRRLDPMYEQAAASLGARPHQVLWRVKLPLLLPSLTAAAGLCFALSMGELSATVMLYPPDWTTLPVRIFAATDRGSLFTGAALAVVLMTTTLLVLLGVSRIRTKASYR
>CP032698.1|AYG82664.1|5411173_5412250_+|Putative-2-aminoethylphosphonate-binding-periplasmic-protein
MPRNLLPVLKPLAAVTTGLVLAAGLSGCSGASSADENAKTVTVYSADGLKGEKGDGWYDRVFKDFEATTGIKVQYVEGGSGEMVQRALREKSNTQADLLITLPPFIQQADGKGLLQRYVPAGADKVDGGAKSPDGTWTSVVNNYFGFIYNKKELKEAPKNWEELLDARYKNKIQYSTPGVAGDGTALLIKAMHDFGGKEAAMEYLRKLQANNVGPSSSTGKLAPKVDKGELLAANGDVQMNHAQSRTMPNLGIWFPGTSGGAKPSSFGLPYAAGLVAHAPHSANGKKLLDFMLSEQAQKQVSEIGGGFASRTDIKATDATAVELAKLMRGVEVFQPDWMDIAKNLPQYVDAWKSATKN
>CP032698.1|AYG82665.1|5412453_5413233_+|Ribonucleotide-monophosphatase-NagD
MAERKPIESWLTDMDGVLIHEGTPIPGADAFLKTLKESGRPFLVLTNNSIYTPRDLHARLMRMGLDVPVENIWTSALATAKFLDDQRPGGTAYVIGEAGLTTALHDIGYVLTDHEPDYVVLGETRTYSFEALTKAIRLINAGARFICTNPDETGPSQEGPLPATGAVAALITKATGKKPYFAGKPNPLMMRTGLNAIGAHSETSAMIGDRMDTDVLAGLEAGMQTFLVLTGLTRPADVESYPFRPSKIVDSIADLVKLV
>CP032698.1|AYG82666.1|5413334_5413901_+|hypothetical-protein
MRIRPITLCAAVAAAALTVLPASPAVAESEPHGSVRVTPGAIAPGGEVELRVGVCSGHEAVGGSDAFDSEVRFDRAGDGGLFAKAHIRSDAQDRDYDVWVTCKDSHGKASGRLTVVRGDHHGDHHDDHSRPTPFRPVHAGGGGAATLAAQEPKEQGPGTRHAVIGLALAAVAAVAVASRSVRRRRGGD
>CP032698.1|AYG82667.1|5413902_5414586_+|hypothetical-protein
MSSARSSGRLVTGLAWAVLLLGLWLWGRDVTNGPGSTSAPITGDIAAVGRPLGVPLPPAHAPLKGATPQRVEIPSIGVAAPVVPRGLDSGGAVDPPPYAQAGTVGWFGGGTRPGEAGAALLVGHVDTESRPAVFYGLSAVRPGQQVKVTGADGTIAEFTIDDVQVFPRSHFDAAQVYGPRQPGRAELRLITCGGTYDRTTKAYTANVVVSAYLTDARDPAPAKPPQP
>CP032698.1|AYG82668.1|5414741_5415971_+|Endoglucanase-A
MGSGGHETTGAEAAHTTLGRPRAPGLGPDNAKSSDGRAEPYPVHDRAATEAPNPVNDGLNLLKGTCMYGSWTHRGRRPAIRAGGLAAATALLAAGCGGSGEGHTPAAASAPSTPLAVSGGPFWVDPDTKAAHQLAAYTRAGDDGRAALIRKIAEQPVGAWIAGDRPEGAVRAATGAAAKAGRMALLVLYNIPHRDCGQFSRGGAPDDDAYRDWVDQVARGIGERPTMVVLEPDAILHLVDGCTPEPFHAARYALLKAAVERLKQQPATKVYVDAGNAGWRSPDALDEPLRRAGIQSADGFAVNVSNFQTTGASREFGERLSAKVGGKHFVIDTSRNGNGPYTEGDPAENWCNPPGRALGERPTTDTASGVIDAYVWAKRPGESDGPCRGGPPAGAWWPEYALALAGNSR

Crispr_ID: CP032698_66

• CRISPR_ID: CP032698_66
• CRISPR_location: 5419997-5420168
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_66

Consensus_repeat	Method
CCCCTGGGGCTCCGCCCCAGACCCC	CRISPRCasFinder

spacers of CP032698_66

>66.1|5420022|48|CP032698|CRISPRCasFinder
GGGGGTCCGCCCGCCCACCCACCCGTGCAGCGCGTTGAACAGGCTGAC
>66.2|5420095|49|CP032698|CRISPRCasFinder
AGGCACTTCGCCCACCCACCCGCCCGTGACGGGGGCTGGTCGGTTCCGG

CRISPR arrays and Neighbor proteins around CP032698_66

CRISPR arrays

The CRISPR arrays of CP032698_66

>merge|CP032698|66|5419997-5420168|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCGGGGGTCCGCCCGCCCACCCACCCGTGCAGCGCGTTGAACAGGCTGACCCCCTGGGGCTCCGCCCCAGACCCCAGGCACTTCGCCCACCCACCCGCCCGTGACGGGGGCTGGTCGGTTCCGGCCCCTGGGGCTCCGCCCCAGACCCC

>CP032698|66|49|5419997-5420168|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCC	GGGGGTCCGCCCGCCCACCCACCCGTGCAGCGCGTTGAACAGGCTGAC
CCCCTGGGGCTCCGCCCCAGACCCC	AGGCACTTCGCCCACCCACCCGCCCGTGACGGGGGCTGGTCGGTTCCGG
CCCCTGGGGCTCCGCCCCAGACCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82670.1|5417714_5419082_+|hypothetical-protein	unknown	unknown	gnl|CDD|259800
CP032698.1|AYG82676.1|5424331_5424796_-|Group-2-truncated-hemoglobin-YjbI	unknown	unknown	gnl|CDD|381284
CP032698.1|AYG82678.1|5426365_5427148_-|Glutamine-transport-ATP-binding-protein-GlnQ	unknown	unknown	gnl|CDD|224051
CP032698.1|AYG82680.1|5427784_5428444_-|Arginine-transport-system-permease-protein-ArtQ	unknown	unknown	gnl|CDD|132049
CP032698.1|AYG82679.1|5427137_5427788_-|Arginine-transport-system-permease-protein-ArtQ	unknown	unknown	gnl|CDD|132048
CP032698.1|AYG82671.1|5419331_5419931_+|GlcNAc-binding-protein-A	unknown	unknown	gnl|CDD|376983
CP032698.1|AYG82674.1|5421528_5422467_+|Lipase-2	unknown	unknown	gnl|CDD|238861
CP032698.1|AYG82666.1|5413334_5413901_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82673.1|5420763_5421261_+|hypothetical-protein	unknown	unknown	gnl|CDD|376573
CP032698.1|AYG82662.1|5409414_5410254_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnU	unknown	unknown	gnl|CDD|237888
CP032698.1|AYG82672.1|5420452_5420812_+|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG82675.1|5422621_5424229_-|Antiseptic-resistance-protein	unknown	unknown	gnl|CDD|184957
CP032698.1|AYG82668.1|5414741_5415971_+|Endoglucanase-A	unknown	unknown	gnl|CDD|376532
CP032698.1|AYG82681.1|5428440_5429319_-|L-cystine-binding-protein-FliY	unknown	unknown	gnl|CDD|270223
CP032698.1|AYG82665.1|5412453_5413233_+|Ribonucleotide-monophosphatase-NagD	unknown	unknown	gnl|CDD|319832
CP032698.1|AYG82664.1|5411173_5412250_+|Putative-2-aminoethylphosphonate-binding-periplasmic-protein	unknown	unknown	gnl|CDD|237887
CP032698.1|AYG82667.1|5413902_5414586_+|hypothetical-protein	unknown	unknown	gnl|CDD|320678
CP032698.1|AYG82677.1|5425395_5426154_-|Transcriptional-repressor-IclR	unknown	unknown	gnl|CDD|224332
CP032698.1|AYG82669.1|5416359_5417703_+|hypothetical-protein	unknown	unknown	gnl|CDD|366659
CP032698.1|AYG82663.1|5410240_5411038_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnV	unknown	unknown	gnl|CDD|132299

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82670.1|5417714_5419082_+|hypothetical-protein	gnl|CDD|259800	cd03402, SPFH_like_u2, Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily. This model summarizes an uncharacterized family of proteins similar to stomatin, prohibitin, flotillin, HflK/C (SPFH) and podocin. The conserved domain common to the SPFH superfamily has also been referred to as the Band 7 domain. Many superfamily members are associated with lipid rafts. Individual proteins of the SPFH superfamily may cluster to form membrane microdomains which may in turn recruit multiprotein complexes. Microdomains formed from flotillin proteins may in addition be dynamic units with their own regulatory functions. Flotillins have been implicated in signal transduction, vesicle trafficking, cytoskeleton rearrangement and are known to interact with a variety of proteins. Stomatin interacts with and regulates members of the degenerin/epithelia Na+ channel family in mechanosensory cells of Caenorhabditis elegans and vertebrate neurons and participates in trafficking of Glut1 glucose transporters. Prohibitin may act as a chaperone for the stabilization of mitochondrial proteins. Prokaryotic HflK/C plays a role in the decision between lysogenic and lytic cycle growth during lambda phage infection. Flotillins have been implicated in the progression of prion disease, in the pathogenesis of neurodegenerative diseases such as Parkinson's and Alzheimer's disease, and in cancer invasion and metastasis. Mutations in the podocin gene give rise to autosomal recessive steroid resistant nephritic syndrome.	4.41878e-83
CP032698.1|AYG82676.1|5424331_5424796_-|Group-2-truncated-hemoglobin-YjbI	gnl|CDD|381284	cd14775, TrHb2_O-like, Truncated hemoglobins, group 2 (O); uncharacterized subgroup. The M- and S families exhibit the canonical secondary structure of hemoglobins, a 3-over-3 alpha-helical sandwich structure (3/3 Mb-fold), built by eight alpha-helical segments. Truncated hemoglobins (TrHbs, 2/2Hb, or 2/2 globins) or the T family globins adopt a 2-on-2 alpha-helical sandwich structure, resulting from extensive and complex modifications of the canonical 3-on-3 alpha-helical sandwich that are distributed throughout the whole protein molecule. TrHbs are classified into three main groups based on their structural properties and named after Mycobacterium sp. genes glbN, glbO, and glbP: TrHb1s (N), TrHb2s (O) and TrHb3s (P).	3.98427e-57
CP032698.1|AYG82678.1|5426365_5427148_-|Glutamine-transport-ATP-binding-protein-GlnQ	gnl|CDD|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	4.11136e-134
CP032698.1|AYG82680.1|5427784_5428444_-|Arginine-transport-system-permease-protein-ArtQ	gnl|CDD|132049	TIGR03004, ectoine_ehuC, ectoine/hydroxyectoine ABC transporter, permease protein EhuC. Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons. Permease subunits EhuC and EhuD are homologous.	3.67992e-64
CP032698.1|AYG82679.1|5427137_5427788_-|Arginine-transport-system-permease-protein-ArtQ	gnl|CDD|132048	TIGR03003, ectoine_ehuD, ectoine/hydroxyectoine ABC transporter, permease protein EhuD. Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.	1.39522e-75
CP032698.1|AYG82671.1|5419331_5419931_+|GlcNAc-binding-protein-A	gnl|CDD|376983	pfam03067, LPMO_10, Lytic polysaccharide mono-oxygenase, cellulose-degrading. This domain is found associated with a wide variety of cellulose binding domains. This is a family of two very closely related proteins that together act as both a C1- and a C4-oxidising lytic polysaccharide mono-oxygenase, degrading cellulose. This domain is also found in baculoviral spheroidins and spindolins, protein of unknown function.	5.48371e-74
CP032698.1|AYG82674.1|5421528_5422467_+|Lipase-2	gnl|CDD|238861	cd01823, SEST_like, SEST_like. A family of secreted SGNH-hydrolases similar to Streptomyces scabies esterase (SEST), a causal agent of the potato scab disease, which hydrolyzes a specific ester bond in suberin, a plant lipid. The tertiary fold of this enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles two of the three components of typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxylic acid.	2.39206e-49
CP032698.1|AYG82673.1|5420763_5421261_+|hypothetical-protein	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.86597e-11
CP032698.1|AYG82662.1|5409414_5410254_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnU	gnl|CDD|237888	PRK15050, PRK15050, 2-aminoethylphosphonate transport system permease PhnU; Provisional.	2.25908e-122
CP032698.1|AYG82672.1|5420452_5420812_+|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.67438e-21
CP032698.1|AYG82675.1|5422621_5424229_-|Antiseptic-resistance-protein	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	1.26524e-66
CP032698.1|AYG82668.1|5414741_5415971_+|Endoglucanase-A	gnl|CDD|376532	pfam01341, Glyco_hydro_6, Glycosyl hydrolases family 6.	3.87146e-80
CP032698.1|AYG82681.1|5428440_5429319_-|L-cystine-binding-protein-FliY	gnl|CDD|270223	cd01002, PBP2_Ehub_like, Substrate binding domain of ectoine/hydroxyectoine specific ABC transport system; the type 2 periplasmic binding protein fold. This family represents the periplasmic substrate-binding component of ABC transport systems that involved in uptake of osmoprotectants (also termed compatible solutes) such as ectoine and hydroxyectoine. To counteract the efflux of water, bacteria and archaea accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.81875e-101
CP032698.1|AYG82665.1|5412453_5413233_+|Ribonucleotide-monophosphatase-NagD	gnl|CDD|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.74357e-130
CP032698.1|AYG82664.1|5411173_5412250_+|Putative-2-aminoethylphosphonate-binding-periplasmic-protein	gnl|CDD|237887	PRK15046, PRK15046, 2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional.	1.08133e-168
CP032698.1|AYG82667.1|5413902_5414586_+|hypothetical-protein	gnl|CDD|320678	cd05829, Sortase_F, Sortase domain found in the class F family of sortases. Class F sortases are mainly present in Actinobacteria, Chlorobacteria and Firmicutes. Their functions are largely unknown.	1.49661e-51
CP032698.1|AYG82677.1|5425395_5426154_-|Transcriptional-repressor-IclR	gnl|CDD|224332	COG1414, IclR, Transcriptional regulator [Transcription].	1.3103e-21
CP032698.1|AYG82669.1|5416359_5417703_+|hypothetical-protein	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	0.000112564
CP032698.1|AYG82663.1|5410240_5411038_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnV	gnl|CDD|132299	TIGR03255, PhnV, 2-aminoethylphosphonate ABC transport system, membrane component PhnV. This membrane component of an ABC transport system is found in Salmonella and Burkholderia lineages in the vicinity of enzymes for the breakdown of 2-aminoethylphosphonate.	4.61015e-54

Protein sequences

>CP032698.1|AYG82671.1|5419331_5419931_+|GlcNAc-binding-protein-A
MRKKQRLGAAVVGLAVAGVSLLATGSASSHGYTDQPISRQKLCANGTVSGCGDIQWEPQSVEGPKGFPAGGPPDGAICAGGNSRFAELDDPRGGTGWPTTKLTGGQSYTFRWQFTARHATTDFRYYLTKQGWNPAQKLTRAALDTQPFLIVPYGGKQPPGTLSHQGVIPSGRSGRHVVVAVWTIADTGNAFYACSDVQL
>CP032698.1|AYG82670.1|5417714_5419082_+|hypothetical-protein
MSMQSNPEPGVGGDAGGVDAGARISLPQLANSGVGEQGSTTAARTPTAPVPDAPAAPAVPPGPALIPVDAGRRVAVIRSENTAEIPVHLLFRDDTGPVPLVPGAGADVVGTGLGGGERPGPGAPAARSGARPGARPPRQAGPRAAVPAPARPATPVDPRIAERPGPVVAGPVAVAVGLLALAGCAAVLCWTGVLPPGLAVLLRLPAYPYRGIRLEQWGLLAVGVSVMVLAFGGLGRGQVGHAWVLSLFGDYRGSVRRTGLVWMSPLLLRRRVDLRLRHWRSEPLGVVDANGTALRVVVLVVWRVRDTARATLAVADHERYLREQVEAAMARVLSQLPADAFHEDAPTLRDVEAVGDALTRVLKSETEPVGIELYSAQPTRIEYAPEVAAAMRRQRVAAIDARHRDAVLTSVVDAVDDTVHRLTSRGLVELDAYERKALVKDLTVAFYTGRGAGEG
>CP032698.1|AYG82669.1|5416359_5417703_+|hypothetical-protein
MEASTPGPVFEEYEPAGACGCPGCADRRRSRLLPVRDGGHPAASGGARRALLAATAASVVLSTGTAAAASPHPVPDGPGANRAADPGPPTEQGGRGGLHGAPGRPADQPATLAPITRAEIINRAKTWVTAAVPYNMEAYWSDGYRQDCSGFVSMAWNLGTNEWTGSLAKFAVRITRDELQPGDILLFHNPANPNKGSHVVIFGGWTDATHAYYTAYEQTPPHAREQATPYAYWKDSASYVPYRYKAVATATGGAVPVADTASSAAAFPGASKFGPGAVNGHVTRVGQMLVKRGGSRFYTEGPGPRWGPADQNATRAFQQAQGWTGADADGIPGARTWALLVQGAGRDIPATLQAPPPAPAAVPAAQPTRPAYPGPSYFRPGQESPYVTQLGRRLVAKGFGTYYTSGPGPRWGEADRRNVEAFQRAQGWSGAEADGYPGPETWRRLFA
>CP032698.1|AYG82668.1|5414741_5415971_+|Endoglucanase-A
MGSGGHETTGAEAAHTTLGRPRAPGLGPDNAKSSDGRAEPYPVHDRAATEAPNPVNDGLNLLKGTCMYGSWTHRGRRPAIRAGGLAAATALLAAGCGGSGEGHTPAAASAPSTPLAVSGGPFWVDPDTKAAHQLAAYTRAGDDGRAALIRKIAEQPVGAWIAGDRPEGAVRAATGAAAKAGRMALLVLYNIPHRDCGQFSRGGAPDDDAYRDWVDQVARGIGERPTMVVLEPDAILHLVDGCTPEPFHAARYALLKAAVERLKQQPATKVYVDAGNAGWRSPDALDEPLRRAGIQSADGFAVNVSNFQTTGASREFGERLSAKVGGKHFVIDTSRNGNGPYTEGDPAENWCNPPGRALGERPTTDTASGVIDAYVWAKRPGESDGPCRGGPPAGAWWPEYALALAGNSR
>CP032698.1|AYG82667.1|5413902_5414586_+|hypothetical-protein
MSSARSSGRLVTGLAWAVLLLGLWLWGRDVTNGPGSTSAPITGDIAAVGRPLGVPLPPAHAPLKGATPQRVEIPSIGVAAPVVPRGLDSGGAVDPPPYAQAGTVGWFGGGTRPGEAGAALLVGHVDTESRPAVFYGLSAVRPGQQVKVTGADGTIAEFTIDDVQVFPRSHFDAAQVYGPRQPGRAELRLITCGGTYDRTTKAYTANVVVSAYLTDARDPAPAKPPQP
>CP032698.1|AYG82666.1|5413334_5413901_+|hypothetical-protein
MRIRPITLCAAVAAAALTVLPASPAVAESEPHGSVRVTPGAIAPGGEVELRVGVCSGHEAVGGSDAFDSEVRFDRAGDGGLFAKAHIRSDAQDRDYDVWVTCKDSHGKASGRLTVVRGDHHGDHHDDHSRPTPFRPVHAGGGGAATLAAQEPKEQGPGTRHAVIGLALAAVAAVAVASRSVRRRRGGD
>CP032698.1|AYG82665.1|5412453_5413233_+|Ribonucleotide-monophosphatase-NagD
MAERKPIESWLTDMDGVLIHEGTPIPGADAFLKTLKESGRPFLVLTNNSIYTPRDLHARLMRMGLDVPVENIWTSALATAKFLDDQRPGGTAYVIGEAGLTTALHDIGYVLTDHEPDYVVLGETRTYSFEALTKAIRLINAGARFICTNPDETGPSQEGPLPATGAVAALITKATGKKPYFAGKPNPLMMRTGLNAIGAHSETSAMIGDRMDTDVLAGLEAGMQTFLVLTGLTRPADVESYPFRPSKIVDSIADLVKLV
>CP032698.1|AYG82664.1|5411173_5412250_+|Putative-2-aminoethylphosphonate-binding-periplasmic-protein
MPRNLLPVLKPLAAVTTGLVLAAGLSGCSGASSADENAKTVTVYSADGLKGEKGDGWYDRVFKDFEATTGIKVQYVEGGSGEMVQRALREKSNTQADLLITLPPFIQQADGKGLLQRYVPAGADKVDGGAKSPDGTWTSVVNNYFGFIYNKKELKEAPKNWEELLDARYKNKIQYSTPGVAGDGTALLIKAMHDFGGKEAAMEYLRKLQANNVGPSSSTGKLAPKVDKGELLAANGDVQMNHAQSRTMPNLGIWFPGTSGGAKPSSFGLPYAAGLVAHAPHSANGKKLLDFMLSEQAQKQVSEIGGGFASRTDIKATDATAVELAKLMRGVEVFQPDWMDIAKNLPQYVDAWKSATKN
>CP032698.1|AYG82663.1|5410240_5411038_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnV
MLVHSRGGRWAARTVFFVLFLPVFALPLLVVVAASFATNWSGALPSGFTTGHYAAATTGESLQALTTSLVTALTASVLALVVGTWAALAAAALGTGGRRFMDALFVLPVAVPSVVVGLAVLVAFSEPPVLLNGTRQIVILAHTVLVTAFAYQSVSAAVRRLDPMYEQAAASLGARPHQVLWRVKLPLLLPSLTAAAGLCFALSMGELSATVMLYPPDWTTLPVRIFAATDRGSLFTGAALAVVLMTTTLLVLLGVSRIRTKASYR
>CP032698.1|AYG82662.1|5409414_5410254_+|Putative-2-aminoethylphosphonate-transport-system-permease-protein-PhnU
MASPARPAPAALWALVPVAVLTAVFLYPLALVVRQSLSPDTGGTSLQAYTDVFASAAFRDALGTTVWLAVGASAGCVVLGFVLALVIAFVPFPGGKVVARFIDVFLSFPSFLITLALLFVYGTVGMANGLWSDVTGTTGTGPFQFLTTPWGVLLAEITYFTPFVMRPLLAAFSQLDTIQLEVASSLGARPARIVRRVILPEALPALAAGGSLVLVMCLNEFGIVLFTGAKGVTTLPMLVYGKAILESDYPAACVVAVVNIVISVGLYGLYRVVSRRAGA
>CP032698.1|AYG82672.1|5420452_5420812_+|hypothetical-protein
MVGIVERLVPDELWELFQRVVPEAPSRPQGGGRRRHGDREVLAAIVFVATSGCTWQQLPSASFGPSGATAHRRFSEWSKARVWAKLHRLVLDELGARGELDWSRCAIDSVNMRALKRGT
>CP032698.1|AYG82673.1|5420763_5421261_+|hypothetical-protein
MRDRLGEHAGPEKGDLTGPNPVDRGKYGSKIHLITERSGLPISVGISGANLHDSQALIPLVKGIPPIRSRRGPRRRKPSKLHADKGYDYAHLRQWLRERGITHRIARKGVESSQRLGRHRWTVERTMAWLAGCRRLHRRYERKADHFLAFTSIACTLICYRRLAK
>CP032698.1|AYG82674.1|5421528_5422467_+|Lipase-2
MNPRLLLTALLTATSTLLSTPTPAPAIPLPSTPHISPTPDFHEYVALGDSWSADVTVLGIDHTYAPSGCAQSAWNYPKQVAARLGVRVFRDATCGGATTVEMTAPQNVGHVPLLAQGVNPAQFDRLTPTTDLVTVGIGGNDVGLADTALGCLNPLPAPLAQPCRTRFAGPGGRDLMSQRIAGAKSRISGVLAGIHQRSPRATVLVVDYLAGVADDHGCYPVVPILDEDLAWFGARLRELNGMLASAAREGGATFVDTYRGSVGHDVCAPDGIRWVEGLLPLSTHPVGPAVSFHPNRLGADHQAATVLSMLGS
>CP032698.1|AYG82675.1|5422621_5424229_-|Antiseptic-resistance-protein
MTNATSTTASTTTGAGLRAGRREWTAFVVLLLPLLLVSMDVSVLYFALPSISRELDPSATQQLWIIDVYAFALAGLLITMGSLGDRIGRRKLLMIGAAAFGLASVTAAYATSADMLIASRALLGVGGATLMPSTMGLVRNMFRDDKQRGQAIGIWSGAMAGGIALGSVLSGVMLEHLWWGSVFLINVPAMVLLLILAPLLVPEFKDPAPGRFDLLGVPLSMGAVLPVVYGLKEFAVDGFSTTSTVCVAVGLLLGAVFVRRQLTRRDAMISRELFRPGRGFGAAISLNSVAAFAMMGSAYFTTQYLQSVLDMSSLRAALWSVAPSLAIGATAPAASAVAQKVNRAYVIAAGFAIGALGFALMALAGTDSLWTVLAGTAVMGMGIVTVMALVSDMALASAPAEKAGSAASLLETGQEFGGALGMAVLGSIGTAVYRSDMPASAPAAARETLGAAVAGADRALATVARDAFVDGMQYAAVGGTLLLVLAAVLAAGMLRGPAAAAKAAAEAQGEARGEARGEAVAGEEVVGGRVAEAVR
>CP032698.1|AYG82676.1|5424331_5424796_-|Group-2-truncated-hemoglobin-YjbI
MTQTPYAWMGGQAALERLTEVFYRQVHKDPLLAPVFAHASPEHPHLVAVWLAEVFGGPAEYSAQHGGHAHMATMHKGHGVTEEQRRRWVELLMDAADEAELPDDPEFRAVFAYYIEWGTRMALVYSGPNPPPASADVPVPKWGWNQTPPWEPAG
>CP032698.1|AYG82677.1|5425395_5426154_-|Transcriptional-repressor-IclR
MALKPEPTAPFHSVQYVLRVLEAISRHGSGVTDVQIARETGLPTAHLTSMLLMLRREGYVEQVADGAYVIGDSMVLLGSGATRQEALETKLQETLTSLRDSVGAAVYISRYIDGEVKITQYADGPRAPKVNEWVDFKSAAHASAVGKCLLTQLDQNGRRDHLSRHKIARLTSRTITSERVLFSKLDSQPATVPVLDLQEYAVGTVCAAVPLTAGSAVGCLALSLPIEHAHRLRAAADTLNRRAAPVVLSLAI
>CP032698.1|AYG82678.1|5426365_5427148_-|Glutamine-transport-ATP-binding-protein-GlnQ
MSADTQIEMPVQNKTGAELIRFENVTKRFGDNTVLDDLCFSARKGKHVTLIGPSGSGKTTILRLLMTLETPDSGTIQVNGTRLYPAGEKERREARKKIGMVFQQFNLFPNMSVLRNITEAPVRVLGLSADEAEERARELLDLVGLGDKRDAKPAQLSGGQQQRVAIARALAMRPEVLLLDEVTSALDPELVAGVLDLLRDIARTTDITMLCVTHEMSFARDISDEVMMFDAGKVIESGPPEKIFGDPDHERTREFLGAIA
>CP032698.1|AYG82679.1|5427137_5427788_-|Arginine-transport-system-permease-protein-ArtQ
MNWDWSAVWDFMPRFGDGVLTTLQILALGSLISFSLGLVWALAFRAPSRFVRWPVNLITEFIRTTPLLVQLFFLFFVLPEWGVKFSALTTGILAIGLHYSTYTAQVYRAGIDAVPKGQWEAATALSLPAHRTWFAVILPQAVRRIAPALGNYVISMLKDTPLLAGISVLEMLQQSRLAGASTFQYTEPLTVVGVAFILIAYPASLFVRSLERRLVR
>CP032698.1|AYG82680.1|5427784_5428444_-|Arginine-transport-system-permease-protein-ArtQ
MTAGLWQHWVLPGIWITLQLTVYSSALAAVVAFGVGLARTHRSRLVRFLAAAYTEIFRGTSALVLMFWLFFVLPPLAGWQLVPMWAAVLALGLSYGAYGAEIVRGALNSVAPAQREAGIALSLTPWQRLRLVLLPQAVPEMIPPFCNLLVELLKGTALVSLLGVGDVSFAAYLVRLATQDSAQIYSVTLVIYFVLAFAITRGMKALERRTKANLGVSTP
>CP032698.1|AYG82681.1|5428440_5429319_-|L-cystine-binding-protein-FliY
MARATSRPRPSIPRRTLLTGAAAVALTGAAACSRVPQGDALARLKSRGSVRLGIAGEVPYGYVNEQGEFTGEAPELAKVIFKRLGIGHVQPVATDFSSLIPGLNSQQFDVVSAGMYINKERCAQVLFADPEYQMLDAFLVRKGNPKNLRGYEDVVRAKARFATGTGYAEIGHAVAAGYPEKDIVILQDQVAGLNAVESGRVDVFAGTALTVREVARKSAKAEATEAFATVVDGKKKIDGGGFAFRPADGALRDAFNAEIHRMKRSGELFRILKPFGFTQDEMTTLTAKELCR

Crispr_ID: CP032698_67

• CRISPR_ID: CP032698_67
• CRISPR_location: 5452326-5452425
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_67

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGGGGC	CRISPRCasFinder

spacers of CP032698_67

>67.1|5452353|46|CP032698|CRISPRCasFinder
TCAGCTGGTTCAACCCGCTGCACGGGCGGTGGGTGGGCGAACGCGT

CRISPR arrays and Neighbor proteins around CP032698_67

CRISPR arrays

The CRISPR arrays of CP032698_67

>merge|CP032698|67|5452326-5452425|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGCTCAGCTGGTTCAACCCGCTGCACGGGCGGTGGGTGGGCGAACGCGTCGGGGTCTGGGGCGGAGCCCCAGGGGC

>CP032698|67|50|5452326-5452425|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGC	TCAGCTGGTTCAACCCGCTGCACGGGCGGTGGGTGGGCGAACGCGT
CGGGGTCTGGGGCGGAGCCCCAGGGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82696.1|5449354_5449879_-|hypothetical-protein	unknown	unknown	gnl|CDD|284603
CP032698.1|AYG82697.1|5450032_5450722_+|Sensory-transduction-protein-regX3	unknown	unknown	gnl|CDD|223816
CP032698.1|AYG82698.1|5450718_5452098_+|Sensor-histidine-kinase-CpxA	unknown	unknown	gnl|CDD|223715
CP032698.1|AYG82704.1|5457654_5458650_-|Lactose-transport-system-permease-protein-LacF	unknown	unknown	gnl|CDD|224096
CP032698.1|AYG82708.1|5461744_5462020_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82699.1|5452633_5454130_+|putative-bifunctional-chitinase/lysozyme	unknown	unknown	gnl|CDD|119360
CP032698.1|AYG82691.1|5443708_5444608_-|hypothetical-protein	unknown	unknown	gnl|CDD|379588
CP032698.1|AYG82703.1|5456815_5457658_-|Lactose-transport-system-permease-protein-LacG	unknown	unknown	gnl|CDD|223472
CP032698.1|AYG82706.1|5460224_5461256_+|Ribose-operon-repressor	unknown	unknown	gnl|CDD|224525
CP032698.1|AYG82707.1|5461262_5461748_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82705.1|5458652_5459993_-|putative-arabinose-binding-protein	unknown	unknown	gnl|CDD|270303
CP032698.1|AYG82694.1|5447732_5448332_+|hypothetical-protein	unknown	unknown	gnl|CDD|173412
CP032698.1|AYG82693.1|5445996_5447502_-|55.5-kDa-and-49.5-kDa-sporulation-proteins	unknown	unknown	unknown
CP032698.1|AYG82700.1|5454291_5454456_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82689.1|5440918_5442508_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82702.1|5455347_5456751_-|Bifunctional-beta-D-glucosidase/beta-D-fucosidase	unknown	unknown	gnl|CDD|274539
CP032698.1|AYG82695.1|5448442_5449300_+|Polyamine-aminopropyltransferase	unknown	unknown	gnl|CDD|223498
CP032698.1|AYG82692.1|5444823_5445429_+|Acid-phosphatase	unknown	unknown	gnl|CDD|366010
CP032698.1|AYG82701.1|5454455_5455220_-|HTH-type-transcriptional-activator-TipA	unknown	unknown	gnl|CDD|133381
CP032698.1|AYG82690.1|5442498_5443602_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82696.1|5449354_5449879_-|hypothetical-protein	gnl|CDD|284603	pfam07218, RAP1, Rhoptry-associated protein 1 (RAP-1). This family consists of several rhoptry-associated protein 1 (RAP-1) sequences which appear to be specific to Plasmodium falciparum.	0.000226795
CP032698.1|AYG82697.1|5450032_5450722_+|Sensory-transduction-protein-regX3	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	7.50974e-68
CP032698.1|AYG82698.1|5450718_5452098_+|Sensor-histidine-kinase-CpxA	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	7.31505e-30
CP032698.1|AYG82704.1|5457654_5458650_-|Lactose-transport-system-permease-protein-LacF	gnl|CDD|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	7.69559e-83
CP032698.1|AYG82699.1|5452633_5454130_+|putative-bifunctional-chitinase/lysozyme	gnl|CDD|119360	cd06543, GH18_PF-ChiA-like, PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in archaea but also in eukaryotes and prokaryotes. PF-ChiA exhibits hydrolytic activity toward both colloidal and crystalline (beta/alpha) chitins at high temperature.	7.12012e-128
CP032698.1|AYG82691.1|5443708_5444608_-|hypothetical-protein	gnl|CDD|379588	pfam14378, PAP2_3, PAP2 superfamily.	1.18309e-63
CP032698.1|AYG82703.1|5456815_5457658_-|Lactose-transport-system-permease-protein-LacG	gnl|CDD|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	2.0399e-74
CP032698.1|AYG82706.1|5460224_5461256_+|Ribose-operon-repressor	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	6.98268e-114
CP032698.1|AYG82702.1|5455347_5456751_-|Bifunctional-beta-D-glucosidase/beta-D-fucosidase	gnl|CDD|274539	TIGR03356, BGL, beta-galactosidase.	0
CP032698.1|AYG82694.1|5447732_5448332_+|hypothetical-protein	gnl|CDD|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	0.000141098
CP032698.1|AYG82695.1|5448442_5449300_+|Polyamine-aminopropyltransferase	gnl|CDD|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	2.47414e-18
CP032698.1|AYG82705.1|5458652_5459993_-|putative-arabinose-binding-protein	gnl|CDD|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.86087e-29
CP032698.1|AYG82701.1|5454455_5455220_-|HTH-type-transcriptional-activator-TipA	gnl|CDD|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	7.12373e-30
CP032698.1|AYG82692.1|5444823_5445429_+|Acid-phosphatase	gnl|CDD|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	9.33933e-55

Protein sequences

>CP032698.1|AYG82698.1|5450718_5452098_+|Sensor-histidine-kinase-CpxA
MRWALVKVCLAVTVMVVVAFAVPLGLVIKEMARDRAFSNAERQAAAIGPTLSITTGRDALERAVASTQSGAEGRMAVHVPADPAVPGSAPVEIGRRRASDEDLDTTRKVIKASISDVSGGSTLLQPTALSSGQIAIVEVFVPEAEVTNGVATAWLVLAGVGIGLIIGSVAVADRLGVRMVRPAQRLAGAAQDLGEGKLGARVPEEGPTELRRAAAAFNSMADQVVQLLANERELAADLSHRLRTPLTVLRLNTASLGDGPAADQTRAAVEQLEREVDTIIRTAREAKPKTQPAGPGAGCDACEVIRERMEFWSALAEDQGREVRLAGVDRPVRIPVARADLVAVLDALLGNVFRHTPEGTAFSVDVHNGEDAVIVLVSDAGPGISDPRAALARGNSGGRPGSTGLGLDIVRRVAESTGGDVRIGHSVLGGTEVRLWIGLGRATPPRRSHRLRPRRPTPA
>CP032698.1|AYG82697.1|5450032_5450722_+|Sensory-transduction-protein-regX3
MASVLVVEDDQFVRSALIRHLTEASHTVRSVGTALEALREVAHFRFDVVILDLGLPDLDGSEALKMLRGITDVPVIIATARDDESEIVRLLNDGADDYLTKPFSVEHLSARMAAVLRRARATADAEPPSRVLQVGGLRVDPLRRQAELDGVRLDLTRREFDLLAFLAGRPGVVVARRELLAEVWQQSYGDDQTIDVHLSWLRRKLGETAAQPRYLHTLRGVGVKLEPPR
>CP032698.1|AYG82696.1|5449354_5449879_-|hypothetical-protein
MTLSWWGVHTVMAGTAYDPPRALPISGDARIEQGSRPDASSTRRPRESPSPSSSAPAKPTKGTAASDKPSSSSSSSPGSSGAPKSASMSGTSGTSDDSADSGAVRGYNVAGGRVVFDLGDSSAQLVSATPASGWRMERWIQTQWIRVTFTRGSETVSVFCTWNGHPPMVEINNT
>CP032698.1|AYG82695.1|5448442_5449300_+|Polyamine-aminopropyltransferase
MAKSSRRRGPEPVVETVDGGLAELIPDRDGSGGWTLLLDGAPQSHVDLDAPGRLTFEYQRRLGHVIDLAAPPGQALNVLHLGGGAFTLARYIAATRPRSTQQIVELDAALVQLVRRELPLDPGARIRVRGGDARAGLAKLPDAWADLVIADVFSGARTPAHLTSTEFLTDVRRVLKPGGTYAANLADGPPLAHLRGQIATAAGVFPELALAADPTVLRGKRFGNAVLVCSAAALPVAELTRRIASDPHPGRVQHGRELADFTGGAVAVSDASAKPSPAPPASAFR
>CP032698.1|AYG82694.1|5447732_5448332_+|hypothetical-protein
MNTDTAIDFTVSGTRTTAVRTPHSAQASAPPAATGCAPEEPCDLVTVPARQGLEAVDIIRRGETPAAVGPVLHDGTCDTLGFLVPPGTAAAWDVPGSACTETNGRGLRIEGLPVAPPVTGSGWLLPPNTTEVTDPGLLRAALGEAARMIEAADGIREADAIRQADGVRRADGTRRADGARARQADAIRQADGTRLPQGR
>CP032698.1|AYG82693.1|5445996_5447502_-|55.5-kDa-and-49.5-kDa-sporulation-proteins
MAPSPDPQAGPRVNARTPRPPERLAREPNAAFRQLRGARSPGEFAASVRRAAREIGEQVACDARYIGRVENGEIRCPNYAYERVFRHMFPGLTLADLGFSSRETVRGRGARPLSAAPPLPSLSPLHVAPRPAECPPDPSPAPSHDPSPAFSHDPSDDHHNPSHDHQNHEESDVLRRAFMTGSTATVAAVSLGLGPVSAHAVQRVGEAEVSAVEEAVRRIRLLDDRHGADGLYQRAAQPLRTAYALLDASASRRSTQERLHSGAGELAISVGWLAHDSGRFGEARSHYAEALATARLAGDPALEAHAFCNMSFLARDMGRPREAMRAAQAGERAARTLGSSRLLSLLALREAGGWAGLGDRSACEESLSRAHSHFARGASGADPEWMSFFVEAELEMLQAQCFSALGDWARAARHARRAAAVQDPHFARNLALYRAELADDLARAGAPAESAAVGQQVLDLLNQVQSTRIQAMLADTSRILAPHRASPEVAAFLERRGSVAV
>CP032698.1|AYG82692.1|5444823_5445429_+|Acid-phosphatase
MAAAAPRILLARHGQTEWSLAGKHTGRTDIPLLEEGRRGAKLLGERLHREPWGGLPGVEVRTSPLVRASETCELAGFGERAEPWDALMEYDYGAYEGMAPPEIQARQPGWFIWRDGVPDGETLAEVAARADEVVAWARSAGRDVLVFAHGHILRVIAARWLGEEVAFAARIRLDPTSLSVLGWAYGEPAVERWNDTGHLER
>CP032698.1|AYG82691.1|5443708_5444608_-|hypothetical-protein
MQPPQHATRPRWWTELPLIALVYAVYSLGRLIVRGDEARAVEHGLSILRLEKAFHLNAEHPLNRLFTHTPALGIPADFVYASLHYLITPAVLIWLFRRRPTQYRAARGWLMTSTLLGLIGFTFLPTCPPRLLPAVQGFTDTMAQYGSYGWWGGEASAPRGLGGMTNQFAAMPSLHVGWALWCGVMLWRFGGSRLTRILAVAYPLTITFVVMGTANHYLLDAVAGAAVMGLGLLLSRPLLRFAERVRTRFTPASRATGAPIVSAGCETSAGERIPGQRTSSDTRSDTRAEAGDSAASTAR
>CP032698.1|AYG82690.1|5442498_5443602_-|hypothetical-protein
MDKGALAEAIGSPSAAFGQSQFAFMRGNAFEAKVKGDGGAELLRLLHERMGAGAEPPRDASSPDLAAAGPEGRAARTSLALREATAAGAWALLDHPMLALEVAGSPAYLEPDAVVVHPDGRWTVVEIKSFPMIDAAADPSKVGAAARQSAVYVLALERVAALVEGAAVDHSVLLVCPKDFSNLPTASVIDVRKQLSVTRRQLTRLARIEEIADALPPGTTFDLDGQSGAALATAVEAVPAVYAPECLAACELAFHCRRRARQQDAVAALGRSLRGELGSLTTIGEVLSAARGESGDPVDPTVAAVRRAAALRAEALAGPPGTNVCAPRTPTGTGTGTDPDSPSTDAGPTAARADGAAARTEAGLPCR
>CP032698.1|AYG82689.1|5440918_5442508_-|hypothetical-protein
MSLISTLARLEAVESGRAQPLTTVRHRHLSERPLVFVPLTTAGEAGAPLGALVGTDRADPTLLVVPQPRDRDLRFTFLADLAEAVLPYLEAYADDVEPAERSETDPETGKKTKVEVELCADAPQLIVPGRAGVDFVRLLGRSMRFRRTAEQDPDAPYPAPPRVPLLGRWFTHYAERARTPGSALLLAATDLLGRHWATGQSSLEDQHLGALLAWIDPPEGESGAEAALRAELARGADGQLLCPPAGPATDPAFDNRLLAPAVERYDRARQALQAAEDGLLADEHLGRLTVAEREIRRLLAAQLMPTWSAVWHALDLLRELPEGERAAARWTSDRWSFTGHRDRIAAGEPPQPRRDDAVTAATKLLRRERAQAELEAGEALDDPLVMAGRRLAGEAFAGEVVEVTPAWSESKRPSPRPLLTLRTDDAPHLAEGAKVYRTLDGKPQKAEFVAYEPGGAVVLRVLDKMGRAKEPAPGSVPGKGDRICWTLFEHEQRGAPKLPDPEATPWTHGGPPGSATAERPDPPTSEDLL
>CP032698.1|AYG82699.1|5452633_5454130_+|putative-bifunctional-chitinase/lysozyme
MGSRTHRRRASAKTKAIGAVVAAAIVGGAAFALTGTAQAASVGAAYTRTSSWTGGYTGQYVITNDSGKTLPDWTLEFDLPAGTTLSSLWNGDQSVKGSHVTVKPPSWAKEGLAPGASVTVGFVTSTSATSTSGTAGDPTGCLINQEKCSVDTGATPEPSGRPTGQPTPKPSQPAGTKPTAQPSKPATAIPTPSKPAGGGTASGARFAPYVDTSLYPAYDILGTAEKTGVKEFTLAFITSGGGCTPLWGGVTDLANDKVAAGIGALRAKGGDARVSFGGASGSELGLVCKSADELAAAYGKVIDAYKLTKVDFDIEGAALPDTAANARRAQAIAKLQASHPGLDVSFTLPVMPEGLTQPGVDLVADAKKNGVKVSAVNIMAMDYGPSYSGDMGGYAIQAATATQAQIKGVLGLSDAAAWAAVAVTPMIGVNDVNVEKFTVADATELVDFAKSKGIGRLSMWSAARDQQCPGGAKNSADPTCSSITQAPLAFTTAFGAYK
>CP032698.1|AYG82700.1|5454291_5454456_-|hypothetical-protein
MGRYSLLPFVLITLPLVCVLALFGVIGWDVVVGVAIATGVLALVARALGRTSGR
>CP032698.1|AYG82701.1|5454455_5455220_-|HTH-type-transcriptional-activator-TipA
MSESTWKVGPLAQACGLTVRTLHHWDTIGLLSPSRRTAGGHREYTGHDIERLYQVLALRSLGLGLDTIAVCLDSGVDPTRVLRDHRESVEAQLTALTNLRDRLVRIEEQAADGSAPTTSALIDALRATGAASPGADQALRRHLDDDQLQALGAHSAAVGPAAHYFLEVEWPELYRRAEELRRSGVAPSDPRVRGLVARMDELGALFGGGDRTLSTGVRSAWREDPAALSGDTSARPGQWDDLADYLDEARKGRK
>CP032698.1|AYG82702.1|5455347_5456751_-|Bifunctional-beta-D-glucosidase/beta-D-fucosidase
MSDRFPPGFLWGAATSAYQIEGATAEDGRTPSIWDTFSHTPGRTADGDTGDRAVDHYHRMREDVALMAELGITSYRFSVSWSRVQPTGRGPAVQLGLDFYRRLVDELLDHNITPALTLYHWDLPQDLEDAGGWPARDTALRFAEYATLVGAALGDRVERWTTLNEPWCSAFLGYASGVHAPGRTEPAASLSAAHHLNLAHGLATSALRSAMPARNQIAVSLNSAVIRPRSQDPADLEAVRRIDDLANGVFHGPMLHGAYPSRLFADTASVTDWSFVRDGDLRAIHQPLDALGLNYYTTSLVSAGAAGSGAARADGHGASAHSPWPGAESVAFHQPPGERTAMGWTIDASGLYDLLLRYTKEVPGLPLLVTENGAAYDDKPGPDGSVHDPDRIRYLYDHLATVRRAMEAGADVRGYYLWSLMDNFEWSYGYGKRFGAVYVDYETLARTPKSSAHWYAELARTGELPEV
>CP032698.1|AYG82703.1|5456815_5457658_-|Lactose-transport-system-permease-protein-LacG
MRAQRAGRQMYGGRLTYAVLIVFTAGSLFPLIWTAIAASRTNTRLAQTPPPFWFGGNLFKNLQIAWTDANMGTALLNTTIVAGSIAAGTVFFSTLAGFAFAKLRFRFKNLLLVLVIGTMMVPPQLSVVPLYMMVAKLSWTDQLQAVILPTLVSAFGVFFMRQYLVEALPTELVEAARVDGASSWRVVWHIVFPVARPAMAVLGMLTFVMAWNDFFWPIIALTQNGSPTVQVALTGLGRGYIPDQSVIMAGALLGTLPLLLAFVLFGRQIVGGIMQGAVKG
>CP032698.1|AYG82704.1|5457654_5458650_-|Lactose-transport-system-permease-protein-LacF
MASDATTAVPSPGPGQEGTAPARARAEERRSRRYRRDMRWSPYALIAPFFVFFAAFGVFPLLYTGWASLHQVELTAPNDMTWVGLRNFSRLLSDDFFWNALRNTFTIGVLSTVPQLLVALGIAHLLNYKLRGSMFFRVAVLTPYATSVAAATLVFVLLFGRDYGMINWALGLVGFDPVDWQNGSWTSQLAVSTIVIWRWTGYNALIYLAAMQAVPVDLYESAALDGASRWQQFRHVTIPALRPTILFTTVVSTIGATQLFGEPLLFNGAAGATGGSDHQFQTLGLYLYEQGWVNLHLGRASAIAWAMFLILLLIGAVNWLVSRALRKGETS
>CP032698.1|AYG82705.1|5458652_5459993_-|putative-arabinose-binding-protein
MRTRTRMSRRLAAFAAVAALGTGLLAGCADDGASPAADGPSAGGGGGGGAKTTLTVGVFGAFGLKEAGLYDAYMKLHPDIEIKQTSIERNENYYPQLLTHLGSGSGLADIQAVEVSNIAEVTATQSGKLEDLSKASGVNKDDFLPWKWAEATTKDGKTVALGTDTGPTGICYRKDLFAKAGLPTDREAVGKLWVGDWNKYLEAGRQYKAKVPSGAAFVDSASGVLNSITGSSATRYYDADGKVVYKTNPAVKQAWDTAAAFATGGLTAKLQQFQPTWDQGFANASFATVSCPAWMLGYIQDKAGASGKDQWDVAAAPKPSNWGGSFLTVPSAGKHKAEAAKLAAWLTAPAQQATLFEKRGSFPSAKAAYGLPAVANAKHAYFGGAPIGQIFAKAAEGTPVQTLGPKDQIIQQNLSDVGMLQVDQKGTSPQQGWQAAVKAIDNALDQ
>CP032698.1|AYG82706.1|5460224_5461256_+|Ribose-operon-repressor
MTAARTVRGRSAGRPTLEEVAVRAGVGRGTVSRVINGSPRVSEETRAAVEAAVAELGYVPNRAARALAANRTDAIALVVPEPEARFFAEPYFSDIVRGVGAALADTEMQLLLTLVGGDRERRRLAQYLASNRVDGVLLVSVHADDPLPDLLEQLGIPVVISGRRSEDEPLASVDSDNFEGARAAVAHLLARGRRGIATITGPLDVYGARRRLDGYRAALTEAGLSELTAHGDFTEEGGRRAMTELLERAPDLDAVFAASDVMASGARQVLRDHGRRIPEDTALIGFDDSSIARHMDPPLTSVRQPIEEMGRAMATLLLTEITTPEPTRPRLVLPTELVVRESS
>CP032698.1|AYG82707.1|5461262_5461748_-|hypothetical-protein
MSIAPEAVRREAVAAWLAGSLNRPRNAHQEWTAYGVALLALGRRFSAVRLAEELVRAAARSTDTAAVNNALHGPVIHDPRGQWFYALVPSAPPVQDLGPYAAHLGLGCYLGVPRVSDNRPDRLASYWVIPPSAPGALCDPDRVIGLIEAGSAALGEGGASG
>CP032698.1|AYG82708.1|5461744_5462020_-|hypothetical-protein
MGTNHSPELGACPHTAVEALKAALGQSGIVLPSLGIDDGSSLGLVNLGRVRPDVALRLAALLGEGPGTRPGPDRAPEARPAGTASPGPEGP

Crispr_ID: CP032698_68

• CRISPR_ID: CP032698_68
• CRISPR_location: 5478388-5478569
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_68

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGGGGGCC	PILER-CR

spacers of CP032698_68

>68.1|5478417|49|CP032698|PILER-CR
CGGGCCATCGAACCCTGCGCTTACGGGCGGGTGGGTGGGGAAAGGGCCT
>68.2|5478495|46|CP032698|PILER-CR
GAACCAACCAACCCCCGTCACGGGCGGGTGGGTGGGCAAAGGGGCT

CRISPR arrays and Neighbor proteins around CP032698_68

CRISPR arrays

The CRISPR arrays of CP032698_68

>merge|CP032698|68|5478388-5478569|PILER-CR
CGGGGTCTGGGGCGGAGCCCCAGGAGGCCCGGGCCATCGAACCCTGCGCTTACGGGCGGGTGGGTGGGGAAAGGGCCTCGGGGTCTGGGGCGGAGCCCCAGGGGGCGGAACCAACCAACCCCCGTCACGGGCGGGTGGGTGGGCAAAGGGGCTCGGGGTCTGGGGCGGAGCCCCAGGGGGCC

>CP032698|68|18|5478388-5478569|PILER-CR
CGGGGTCTGGGGCGGAGCCCCAGGAGGCC	CGGGCCATCGAACCCTGCGCTTACGGGCGGGTGGGTGGGGAAAGGGCCT
CGGGGTCTGGGGCGGAGCCCCAGGGGGCG	GAACCAACCAACCCCCGTCACGGGCGGGTGGGTGGGCAAAGGGGCT
CGGGGTCTGGGGCGGAGCCCCAGGGGGCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82720.1|5472681_5474487_-|Aerobactin-synthase	unknown	unknown	gnl|CDD|226715
CP032698.1|AYG82722.1|5475040_5476336_-|L-lysine-N6-monooxygenase	unknown	unknown	gnl|CDD|226017
CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
CP032698.1|AYG82718.1|5470729_5470897_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82717.1|5470382_5470664_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG82721.1|5474483_5475044_-|N(6)-hydroxylysine-O-acetyltransferase	unknown	unknown	gnl|CDD|379237
CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain	unknown	unknown	gnl|CDD|227111
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	unknown	unknown	gnl|CDD|224857
CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit	unknown	unknown	gnl|CDD|178415
CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG	unknown	unknown	gnl|CDD|163676
CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase	unknown	unknown	gnl|CDD|99743
CP032698.1|AYG82716.1|5468506_5470324_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	unknown	unknown	gnl|CDD|234729
CP032698.1|AYG82719.1|5471022_5472612_+|Beta-N-acetylhexosaminidase	unknown	unknown	gnl|CDD|119336
CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB	unknown	unknown	gnl|CDD|99790
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	unknown	unknown	gnl|CDD|374030
CP032698.1|AYG82715.1|5467832_5468402_+|Succinate-acetate/proton-symporter-SatP	unknown	unknown	gnl|CDD|366504
CP032698.1|AYG82714.1|5467144_5467666_+|hypothetical-protein	unknown	unknown	gnl|CDD|366180
CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC	unknown	unknown	gnl|CDD|223687

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82720.1|5472681_5474487_-|Aerobactin-synthase	gnl|CDD|226715	COG4264, RhbC, Siderophore synthetase component [Secondary metabolites biosynthesis, transport, and catabolism].	1.69693e-167
CP032698.1|AYG82722.1|5475040_5476336_-|L-lysine-N6-monooxygenase	gnl|CDD|226017	COG3486, IucD, Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	0
CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	3.09476e-168
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	gnl|CDD|374030	pfam15698, Phosphatase, Phosphatase. Members of this family have phosphatase activity.	1.42957e-133
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	5.70484e-31
CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.62199e-13
CP032698.1|AYG82714.1|5467144_5467666_+|hypothetical-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	1.25596e-21
CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	gnl|CDD|224857	COG1946, TesB, Acyl-CoA thioesterase [Lipid metabolism].	6.5483e-122
CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit	gnl|CDD|178415	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain.	0
CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG	gnl|CDD|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	9.59339e-157
CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase	gnl|CDD|99743	cd06450, DOPA_deC_like, DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.	5.02668e-121
CP032698.1|AYG82716.1|5468506_5470324_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP032698.1|AYG82719.1|5471022_5472612_+|Beta-N-acetylhexosaminidase	gnl|CDD|119336	cd06568, GH20_SpHex_like, A subgroup of the Glycosyl hydrolase family 20 (GH20) catalytic domain found in proteins similar to the N-acetylhexosaminidase from Streptomyces plicatus (SpHex). SpHex catalyzes the hydrolysis of N-acetyl-beta-hexosaminides. An Asp residue within the active site plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself. Proteins belonging to this subgroup lack the C-terminal PKD (polycystic kidney disease I)-like domain found in the chitobiases.	0
CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB	gnl|CDD|99790	cd06193, siderophore_interacting, Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from transferrin and lactoferrin for bacterial uptake, contributing to pathogen virulence. Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport mechanism of photosystem I. FNR transfers electrons from reduced ferredoxin to FAD (forming FADH2 via a semiquinone intermediate) and then transfers a hydride ion to convert NADP+ to NADPH. FNR has since been shown to utilize a variety of electron acceptors and donors and has a variety of physiological functions including nitrogen assimilation, dinitrogen fixation, steroid hydroxylation, fatty acid metabolism, oxygenase activity, and methane assimilation in a variety of organisms. FNR has an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) flavin sub-domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal moeity may contain a flavin prosthetic group (as in flavoenzymes) or use flavin as a substrate. Because flavins such as FAD can exist in oxidized, semiquinone (one-electron reduced), or fully reduced hydroquinone forms, FNR can interact with one and two electron carriers. FNR has a strong preference for NADP(H) vs NAD(H).	4.55184e-62
CP032698.1|AYG82715.1|5467832_5468402_+|Succinate-acetate/proton-symporter-SatP	gnl|CDD|366504	pfam01184, Grp1_Fun34_YaaH, GPR1/FUN34/yaaH family. The Ady2 protein is required for acetate in Saccharomyces cerevisiae, and is probably an acetate transporter. A homolog in Yarrowia lipolytica (GPR1) has a role in acetic acid sensitivity.	6.45181e-14
CP032698.1|AYG82721.1|5474483_5475044_-|N(6)-hydroxylysine-O-acetyltransferase	gnl|CDD|379237	pfam13523, Acetyltransf_8, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	6.06451e-59
CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC	gnl|CDD|223687	COG0614, FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism].	9.11851e-20

Protein sequences

>CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase
MRAHLLNDTTAEHYRRSVTEGVERVARKLATTRRPFSGVGVDDLAPVIDRIDLDAPLGDTSAVLDELEDVYLRDAVYFHHPRYLAHLNCPVVIPAVLGEAVLSAVNSSLDTWDQSAGGTLIERRLIDWTAGRIGLGPAADGVFTSGGTQSNLQSLLLAREEAKTTDLARLRVFASECSHFSVQKSAQLLGMGRDSVVSIPTDHDKRMQTLALARALERCVSEGNVPMAVVATAGTTDFGSIDPLPGIAELCAQYGAWMHVDAAYGCGLLASPTPARRALLDGIERADSVTVDYHKSFFQPVSSSAVLVRDASTLRHATYHADYLNPRRAAEERIPNQVDKSLQTTRRFDALKLWMTLRTMGADGLGSLFDEVCELAEQGWQLLAADPRYDVVVQPTLSTLVFRYIPATITSPAEIDRANLYARKALFASGEAVVAGTKSGGRQYLKFTLLNPETGVDDIAAVLDLIAGHAEQYLGENLVHAS
>CP032698.1|AYG82722.1|5475040_5476336_-|L-lysine-N6-monooxygenase
MSTRPETPGTGEAYDFIGIGLGPFNLGLACLAEPIEELNGLFLETKPDFEWHSGMFLEGAHLQTPFLSDLVTLADPTSPYSFLNYLKESGRLYSFYIRENFYPLRTEYNDYCRWAAAKLSSVRFNRTVREVTYDESDQTYLVATTTGEAYRARRLVLGTGTPPHLPEPCRGLGGDLLHNSRYLEHREALQKKQSITVVGSGQSAAEIYYDLLSEIDVHGYRLNWVTRSPRFFPLEYTKLTLEMTSPEYIDYFHALPEATRYRLESTQKGLFKGIDSELINAIFDLLYQKSLKGPVPTRLLSNSALTAAGYDTTSGTYTLGLRQEEQEKDYTLSTQGLVLATGYRYAEPEFLAPVSDRLRRDGRGRFDVARNYSIDTTGHGVFLQNAGVHTHSITSPDLGMGAYRNAYIIGELLGREYYRVEKSIAFQEFAI
>CP032698.1|AYG82721.1|5474483_5475044_-|N(6)-hydroxylysine-O-acetyltransferase
MSPQTSLGSLTFRPLDPLSDAELVHSWVTHPKAAFWLMGDAKLQDVEREYMAITAHPHHHALIGLHEGEPAFLMEHYDPRHVELVGLYEPLPGDVGMHFLVAPTEAPLHGFTRAVITAVMEELFADPATERVVVEPDVANTAVHALNEAVGFEIAGRIAKPEKDAYLSFCTREQFRTALARKAAAR
>CP032698.1|AYG82720.1|5472681_5474487_-|Aerobactin-synthase
MTIDTAVTHLTPELWAEANRLLIRKALAEFAHERLITPEPLGDPHASSTTTRPGEAPFRVRADEGPVEYRFTASRLALDHWQVFPESISRHDGERELPLDALDFFLDLRSSLGLSDAILPVYLEEISSTLSGTAYKLTKPQITSAELARSGFQAIETGMTEGHPCFVANNGRLGFGIHEYLAYAPETASPVRLLWLAARRDRATFTAGAGLDHETLMRDELGGPALDRFAAQLADRGLDSADYLLLPVHPWQWWNKLSVTFAAEIAQERLVLLGEGDDDYLAQQSIRTFFNTSDPAKHYVKTALSVLNMGFMRGLSAAYMEATPAINDWLAGLIAADDTFRAARFSIIRERAAIGYRHEQYERATDRYSAYRKMLAALWRESPVPSLEPGERLATMASLLHVDRDGASFAGALIAESGRAPAEWLRGYLDAYLVPVLHSFYAYDLVFMPHGENVILVLGEDGTVSRAIFKDIAEEIAVMDPDAVLPPAVERIRADVPEELRLLSVFTDVFDCFFRFLNAALATEGILEESVFWRTVAECVTAYQDSHPELADRFKQDDLFAPDFALSCLNRLQLRDNAQMVDLADPAGALQLVGTLANPIA
>CP032698.1|AYG82719.1|5471022_5472612_+|Beta-N-acetylhexosaminidase
MRQRQRRTFARLLGSLVLVAGAGLTSVGASAAPAAGAPRPLGQIVPAPASVSAGGTAYTIAAATPIRVSGGSPEAQRIGDYLAGVLRPSTGYALPVTAAAGDDGIRLLLGADDDALGDEGYRLTSRGGSLTIAANEPAGLFHGVQTLRQLLPANVEKRTKQSGPWKVAGGTVTDFPRYAYRGAMIDVSRHFFTVDQVERYIDQLALYKINELHLHLSDDQGWRIAVDSWPRLAPYGGQTQVGGAKGGFYTKDDYKAILAHASSRYMEVVPEIDTPGHINAALASYAELNCNGVAPPLYTGTKVGFSSLCVPKDVTYRFFDDVVREIAALTPGRYVHIGGDEAQSTSKEDYETFMDRAQPVVGKYGKTVMAWHQIVEADPVEGAVAQYWGTLGNEAEVAAAARAGTRLVMSPANRAYLDMKYDAKSPLGTNWAGYVEVDKSYQWDPDTFVEGVPAEAVLGVEAPIWSETLSTSAQIEYMAFPRLQGIAEIGWSPASTHDWASYKVRLAQQGPRMAALGIAYYRSPLVPWV
>CP032698.1|AYG82718.1|5470729_5470897_+|hypothetical-protein
MITHLVWTRKGPETARKGPRRAGRGRTRFSVARLPVPSFRMIFGPARLAPHIPGP
>CP032698.1|AYG82717.1|5470382_5470664_-|hypothetical-protein
MLERRNPSSHDDLVDHLVRSTALQRGEAARVVLEVLAYFDETYEEFVRRRHRELQSGGAVNAEIFERIAAELPHRAVAPPELSLRQLRRIVYG
>CP032698.1|AYG82716.1|5468506_5470324_-|Glutamine--fructose-6-phosphate-aminotransferase-[isomerizing]
MCGIVGYIGKRDVAPLLLEGLARLEYRGYDSAGMVVNTPKSGALKMVKAKGRVRDLEARVPKRFAGTTGIAHTRWATHGAPSDVNSHPHLDPENKVAVVHNGIVDNAAELRVKLEAEGVVFASDTDTEVITHLIARSAADSLEEKVREALKVIEGTYGIAVMHADFADRIVVARNGSPVILGIGEKEMLVASDVAALIAHTRQVVTLNDGEMATLKADDFRTYTTSGTLTNTTPETVEWEAASFDMGGHDTYMHKEMSEQAEAVDRVLRGRIDDRFSTVHLGGLNLDAREARGVRRIKILGCGTSYHAGMIGAGLIEELARIPADAEPASEFRYRNPVVDPDTLYIAVSQSGETYDVLAAVQELKRKGARVLGVVNVVGSAIAREADGGTYVHAGPEVCVVSTKCFTNTVVAFALLALHLGRIRDLSVADGKRIIEGLRKLPGQIEEILAMEPEIEKLAQEYAGAQSMMFIGRVRGYPVALEASLKLKEISYIHAEAYPASELKHGPLALIEPALPTVAIVPNDDLLEKNRAALEEIKARSGRILAVAHQHQEKADHTIVVPKNEDELDPILMGIPLQLFAYHTALAMGRDIDKPRNLAKSVTVE
>CP032698.1|AYG82715.1|5467832_5468402_+|Succinate-acetate/proton-symporter-SatP
MDNEVPAGSTTSTLGHLALGLTLLAFGLGTTRVIDGVTVADSVSIATYIGGIGLFVLGVLAFRDQDAFTGTAFAGLGAFWFTWAAGADTKFSSNAAGLFLVLFALLALSLAAGAAGTGLLRQGTYGLLFLALVLLAIGQFAGSSSLAKVAGWVAVVAGAVAWYGATAALAKWPTALPRRAAGRGVTATG
>CP032698.1|AYG82714.1|5467144_5467666_+|hypothetical-protein
MAGHEFSEPADRKQVADPTSDLQAATEPRHSCDPAFRHGVVVGFDGSMSSERALAYAIGMAKRSGSGLIIVHVANRLPTTVWAGCEPPVFVDVPDHRTEVLGLELACADYLAEVPWILVERGGDICHELEEVGREYAADAIVVGSTHGIVGRIFGSVAGRLARRAQRPVVVIP
>CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB
MPAPAETAIAPFRLFDLRVVRARRLGRSLMRVTFGGFGDEDLSSFAAGGRDQSLSLFLPHPGQEAPVLPPVDDADGWWAAYRALPDGIRAVMRSYTVRAQRRAPLGGPGEIDIDFALHGDGGPASRWARSVRAGGRVTVLGPAVADNTAVRFRPPAGTDSVVIWADETALPAAAGILEWLPSGLPAQVWITAPATPEALPRVTAADARVTWLPSVSPLDAIRSAPLPGASPYVWIAGEASHVRSLRRHFVGERGLERGRVTFVGYWRRGRTEDDLRAA
>CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC
MPHARASLPTRRGLLAMGGAIGIGAALAACGGGDKKSGSADGATGAAKSGPWSFKDDRGQTAQTKAAPKNIVAFTGTAAALFDYGITVKGVFGPTKTKDGNADVQAGSLDISKVEVIGNTYGEFSVEKYAALQPDVLITDMWQKDVLWYVPDNSKDKILKLAPSVALWAADQSMPAALQRRADLAKSLGADLNAKNVTDAKAAFEKASARLRAAAKANPGIKVLLGSASPDLFYVSEAKRSCDTRYFQELGVRFVTPKVDSQGFFESLSWENVGKYPADLILMDNRTGTLQPADLGSKPTWAQLPAVKAHQVVPRLTEPIYSYARVAPIVDALAQAIENAKKVA
>CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase
MPLDHRLTPEHEELRRTVEEFAHDVIAPKIGDFYERHEFPYEIVREMGRMGLFGLPFPEEYGGMGGDYLALGIALEELARVDSSVAITLEAGVSLGAMPIFRFGTEEQKRQWLPRLCSGEALGAFGLTEPDCGSDAGGTRTTAVRDGDEWVINGSKCFITNSGTDITGLVTVTAVTGRKDDGRPLISSIIVPSGTPGFTVAAPYSKVGWNASDTRELSFSDVRVPVANLLGEEGRGYAQFLRILDEGRIAISALATGLAQGCVDESVKYAKERHAFGRPIGDNQAIQFKIADMELRAHMARVGWRDAASRLVHGEPFKKEAALAKLYSSTVAVDNAREGTQIFGGYGFMNEYPVARMWRDSKILEIGEGTSEVQRMLIARELGLPA
>CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG
MTDLPMVVPAEGLPARVRIHEVGARDGLQNEKTVVPTEVKAEFVHRLAAAGLTTVEATSFVHPKWVPQLADAEALFPMLGDLDGVALPVLVPNERGLDRALALGATRIAVFASATESFAKANLNRTVDESLAMFEPVVARAKADGAHVRGYLSMCFGDPWEGAVPVAQVVRVAKALMELGCDELSLGDTIGVATPAHVGALLTGLNDRSIATDAIGVHFHDTYGQALANTFAALQHGVSTVDASAGGLGGCPYAKSATGNLATEDLVWMLQGLGVDTGVDLGQLTATSVWMAEQLGRPSPSRTVRALSHQES
>CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain
MFTTVLVANRGEIAVRVIRTLRQLGIRSVAVFSDADAEARHVREADTAVRIGPAAASESYLRPELLIEAARRTGAQAVHPGYGFLAENAGFAQACAEAGLVFIGPPAEAISLMGDKIRAKETVQKAGVPVVPGSSGSGLSDAQLADAAREIGMPVLLKPSAGGGGKGMRLVREEALLGDEIAAARREARASFGDDTLLVERWIDRPRHIEIQVLADNHGHVIHLGERECSLQRRHQKIIEEAPSVLLDEATRAAMGEAAVQAARSCGYSGAGTVEFIVPGSDPSSYYFMEMNTRLQVEHPVTELITGVDLVEWQLRVAAGEQLPYEQKDITLTGHAIEARLCAEDPSRGFLPSGGTVLALREPQGDGVRTDSGLSEGTEVGSLYDPMLSKVIAYGPDRATALRKLRAALADTVTLCVPTNAGFLRRLLAHPAVVAGELDTGLVEREADSLVPDGVPEEVYAAAAAVRLDALRPAPTDGWTDPFAVPSGWRMGGEPKALAFPLRVSGLEPVTHPAPTTARVTADRVTVELDGLTHTFHRAGAWLGRDGDSWHVTDHDAVEAALSGRTHGGADTLAAPMPGTVTVVKVAVGDQVDAGQSLLVVEAMKMEHVISAPHAGTVTELDVTPGSTVAMDQVLAVVTPAVQESPQDSSQDSSQKSLEESS
>CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit
MQQAPVLGSAADPASAAWRANEAAHRTLGEELRARLAAARLGGGERSRQRHVARGKLLPRDRVDTLLDPGSPFLELAPLAAEGMYGGQAPAAGVIAGIGRVSGRECVIVANDATVKGGTYYPMTVKKHLRAQEVALENRLPCLYLVDSGGAFLPMQDEVFPDRDHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLVKAATGEVVTAEELGGGEVHAKVSGVTDHLAEDDAHALRIVRNIVATLPERGPLPWSVEPAEEPKADPFGLYGAVPVDSRTPYDVREVIARVVDGSRFQEFKSEFGQTLVTGFARIHGHPVGIVANNGILFSESAQKGAHFIELCDQRGLPLVFLQNISGFMVGRDYEAGGIAKHGAKMVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMGGEQAASVLATVKRDQLGDDWSAEDEEAFKAPIREQYETQGNAYYATARLWDDGVIDPVDTRQVLGLALTACANAPLTDPAFGVFRM
>CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R
MSTRTDAPTRREQILREAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFAGKDAMLAELLVGISGRLYDGGRKRVAEAAGDPERLLGALIDGHIDFALDDRALITLHDRELDRLRDSDRKLVRQLQRQYVELWVGVVRELYPAVAEAEVRGAVHAVFGLLNSTPHLGSYGSGLPGRAATETLLRRLAHGAFASLAPLAGR
>CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase
MGNMPIPSRAALVDHLVRTRIAGDVATPRDNNLSHYRRLANGDRHYWLGLELGDRWTDEQDVLAVMAERCGVVDDPGHRTGQDTIDPELTVDGLERMAARLRKAAAGRERVLFATGHPGALIDVHSRTAAALRSAGCDIVRIPGGLTADEGYVVQFADVAVFERGASLWHTHSPEPMRAILDALETPPDLVVADHGWAGCAGQRGVDAVGYADSNDPALFLAEAEGTLQVTVPLDDHVVDPRFYEPMTAYLLDAAGLS
>CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein
MHQLSRTHAWAHAPDRRYLHVMTDRRAYPSDLSDARWELIEPVLSVWRYERHGRALGFGRPPEHDLREIMNAILYVDRTGVQWRYLPHDFPNWNTVYGYFAKWQSDGIFAQLNGLLRELVRQREGRNAEPSACVIDAQSVKTSTSVPATSQGTDNAKKIVGRKRSIVTDTIGLLIAVLVTAASVQDSVAGTQLLDQVSAEHSSIRKVWVDGGYRQHFVEHAATLGIDMEITARTPGTRGFTPIPKRWAVERTYGWLMLHRRLARDYETRTARSEAMIHLAMTDLMARRLTGESTISWRDPANDNQPPISG
>CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2
MHQALESLLDLLDLERIEEDIFRGRSRSALIPRVFGGQVAAQALVAAGRTVPAERTAHSLHAYFLRAGDPGAPIVYTVDRIRDGASFTTRRVVAIQHGQPIFHLSASFQRYEEGMEHQAAMPPAPDPESLPTAAEMLPRYASAFRDEGVVDRLIEARAAVDLRYVDAPPWASVGTPREPRSQVWFRTNGKLADDPLLHVCLATYVSDMTLLDSVLLAHGRGGWAVGDVVGASLDHAMWFHRPFRADEWLLYDQESPSASGGRGLGQARIYTQDGRLAITVIQEGVVRVPRP

Crispr_ID: CP032698_69

• CRISPR_ID: CP032698_69
• CRISPR_location: 5488359-5488459
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_69

Consensus_repeat	Method
CCTGGGGCTCCGCCCCAGACCCCG	CRISPRCasFinder

spacers of CP032698_69

>69.1|5488383|53|CP032698|CRISPRCasFinder
GGCACCTCGCCCACCCACCCGCCCGTGCCCCGGGGTTGGATGGTTCTGGGGCT

CRISPR arrays and Neighbor proteins around CP032698_69

CRISPR arrays

The CRISPR arrays of CP032698_69

>merge|CP032698|69|5488359-5488459|CRISPRCasFinder
CCTGGGGCTCCGCCCCAGACCCCGGGCACCTCGCCCACCCACCCGCCCGTGCCCCGGGGTTGGATGGTTCTGGGGCTCCTGGGGCTCCGCCCCAGACCCCG

>CP032698|69|51|5488359-5488459|CRISPRCasFinder
CCTGGGGCTCCGCCCCAGACCCCG	GGCACCTCGCCCACCCACCCGCCCGTGCCCCGGGGTTGGATGGTTCTGGGGCT
CCTGGGGCTCCGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase	unknown	unknown	gnl|CDD|283275
CP032698.1|AYG82722.1|5475040_5476336_-|L-lysine-N6-monooxygenase	unknown	unknown	gnl|CDD|226017
CP032698.1|AYG82739.1|5501081_5501468_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)	unknown	unknown	gnl|CDD|173849
CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase	unknown	unknown	gnl|CDD|212538
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain	unknown	unknown	gnl|CDD|227111
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	unknown	unknown	gnl|CDD|224857
CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit	unknown	unknown	gnl|CDD|178415
CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein	unknown	unknown	gnl|CDD|224055
CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase	unknown	unknown	gnl|CDD|366376
CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|223107
CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein	unknown	unknown	gnl|CDD|377939
CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase	unknown	unknown	gnl|CDD|99743
CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG	unknown	unknown	gnl|CDD|163676
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	unknown	unknown	gnl|CDD|374030
CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB	unknown	unknown	gnl|CDD|99790
CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC	unknown	unknown	gnl|CDD|223687

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase	gnl|CDD|283275	pfam05576, Peptidase_S37, PS-10 peptidase S37. These serine proteases have been found in Streptomyces species.	0
CP032698.1|AYG82722.1|5475040_5476336_-|L-lysine-N6-monooxygenase	gnl|CDD|226017	COG3486, IucD, Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	0
CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase	gnl|CDD|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	2.75366e-125
CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	3.09476e-168
CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)	gnl|CDD|173849	cd01160, LCAD, Long chain acyl-CoA dehydrogenase. LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer.	4.61967e-145
CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase	gnl|CDD|212538	cd11592, Agmatinase_PAH, Agmatinase-like family includes proclavaminic acid amidinohydrolase. This agmatinase subfamily contains bacterial and fungal/metazoan enzymes, including proclavaminic acid amidinohydrolase (PAH, EC 3.5.3.22) and Pseudomonas aeruginosa guanidinobutyrase (GbuA) and guanidinopropionase (GpuA). PAH hydrolyzes amidinoproclavaminate to yield proclavaminate and urea in clavulanic acid biosynthesis. Clavulanic acid is an effective inhibitor of beta-lactamases and is used in combination with amoxicillin to prevent the beta-lactam rings of the antibiotic from hydrolysis and, thus keeping the antibiotic biologically active. GbuA hydrolyzes 4-guanidinobutyrate (4-GB) into 4-aminobutyrate and urea while GpuA hydrolyzes 3-guanidinopropionate (3-GP) into beta-alanine and urea. Mutation studies show that significant variations in two active site loops in these two enzymes may be important for substrate specificity. This subfamily belongs to the ureohydrolase superfamily, which includes arginase, agmatinase, proclavaminate amidinohydrolase, and formiminoglutamase.	6.02255e-167
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	5.70484e-31
CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	gnl|CDD|224857	COG1946, TesB, Acyl-CoA thioesterase [Lipid metabolism].	6.5483e-122
CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit	gnl|CDD|178415	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain.	0
CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.1722e-168
CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.62199e-13
CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit	gnl|CDD|223107	COG0028, IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism].	6.88462e-137
CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein	gnl|CDD|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	3.65701e-23
CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase	gnl|CDD|99743	cd06450, DOPA_deC_like, DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.	5.02668e-121
CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG	gnl|CDD|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	9.59339e-157
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	gnl|CDD|374030	pfam15698, Phosphatase, Phosphatase. Members of this family have phosphatase activity.	1.42957e-133
CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB	gnl|CDD|99790	cd06193, siderophore_interacting, Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from transferrin and lactoferrin for bacterial uptake, contributing to pathogen virulence. Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport mechanism of photosystem I. FNR transfers electrons from reduced ferredoxin to FAD (forming FADH2 via a semiquinone intermediate) and then transfers a hydride ion to convert NADP+ to NADPH. FNR has since been shown to utilize a variety of electron acceptors and donors and has a variety of physiological functions including nitrogen assimilation, dinitrogen fixation, steroid hydroxylation, fatty acid metabolism, oxygenase activity, and methane assimilation in a variety of organisms. FNR has an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) flavin sub-domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal moeity may contain a flavin prosthetic group (as in flavoenzymes) or use flavin as a substrate. Because flavins such as FAD can exist in oxidized, semiquinone (one-electron reduced), or fully reduced hydroquinone forms, FNR can interact with one and two electron carriers. FNR has a strong preference for NADP(H) vs NAD(H).	4.55184e-62
CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC	gnl|CDD|223687	COG0614, FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism].	9.11851e-20

Protein sequences

>CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase
MGNMPIPSRAALVDHLVRTRIAGDVATPRDNNLSHYRRLANGDRHYWLGLELGDRWTDEQDVLAVMAERCGVVDDPGHRTGQDTIDPELTVDGLERMAARLRKAAAGRERVLFATGHPGALIDVHSRTAAALRSAGCDIVRIPGGLTADEGYVVQFADVAVFERGASLWHTHSPEPMRAILDALETPPDLVVADHGWAGCAGQRGVDAVGYADSNDPALFLAEAEGTLQVTVPLDDHVVDPRFYEPMTAYLLDAAGLS
>CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R
MSTRTDAPTRREQILREAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFAGKDAMLAELLVGISGRLYDGGRKRVAEAAGDPERLLGALIDGHIDFALDDRALITLHDRELDRLRDSDRKLVRQLQRQYVELWVGVVRELYPAVAEAEVRGAVHAVFGLLNSTPHLGSYGSGLPGRAATETLLRRLAHGAFASLAPLAGR
>CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit
MQQAPVLGSAADPASAAWRANEAAHRTLGEELRARLAAARLGGGERSRQRHVARGKLLPRDRVDTLLDPGSPFLELAPLAAEGMYGGQAPAAGVIAGIGRVSGRECVIVANDATVKGGTYYPMTVKKHLRAQEVALENRLPCLYLVDSGGAFLPMQDEVFPDRDHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLVKAATGEVVTAEELGGGEVHAKVSGVTDHLAEDDAHALRIVRNIVATLPERGPLPWSVEPAEEPKADPFGLYGAVPVDSRTPYDVREVIARVVDGSRFQEFKSEFGQTLVTGFARIHGHPVGIVANNGILFSESAQKGAHFIELCDQRGLPLVFLQNISGFMVGRDYEAGGIAKHGAKMVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMGGEQAASVLATVKRDQLGDDWSAEDEEAFKAPIREQYETQGNAYYATARLWDDGVIDPVDTRQVLGLALTACANAPLTDPAFGVFRM
>CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain
MFTTVLVANRGEIAVRVIRTLRQLGIRSVAVFSDADAEARHVREADTAVRIGPAAASESYLRPELLIEAARRTGAQAVHPGYGFLAENAGFAQACAEAGLVFIGPPAEAISLMGDKIRAKETVQKAGVPVVPGSSGSGLSDAQLADAAREIGMPVLLKPSAGGGGKGMRLVREEALLGDEIAAARREARASFGDDTLLVERWIDRPRHIEIQVLADNHGHVIHLGERECSLQRRHQKIIEEAPSVLLDEATRAAMGEAAVQAARSCGYSGAGTVEFIVPGSDPSSYYFMEMNTRLQVEHPVTELITGVDLVEWQLRVAAGEQLPYEQKDITLTGHAIEARLCAEDPSRGFLPSGGTVLALREPQGDGVRTDSGLSEGTEVGSLYDPMLSKVIAYGPDRATALRKLRAALADTVTLCVPTNAGFLRRLLAHPAVVAGELDTGLVEREADSLVPDGVPEEVYAAAAAVRLDALRPAPTDGWTDPFAVPSGWRMGGEPKALAFPLRVSGLEPVTHPAPTTARVTADRVTVELDGLTHTFHRAGAWLGRDGDSWHVTDHDAVEAALSGRTHGGADTLAAPMPGTVTVVKVAVGDQVDAGQSLLVVEAMKMEHVISAPHAGTVTELDVTPGSTVAMDQVLAVVTPAVQESPQDSSQDSSQKSLEESS
>CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG
MTDLPMVVPAEGLPARVRIHEVGARDGLQNEKTVVPTEVKAEFVHRLAAAGLTTVEATSFVHPKWVPQLADAEALFPMLGDLDGVALPVLVPNERGLDRALALGATRIAVFASATESFAKANLNRTVDESLAMFEPVVARAKADGAHVRGYLSMCFGDPWEGAVPVAQVVRVAKALMELGCDELSLGDTIGVATPAHVGALLTGLNDRSIATDAIGVHFHDTYGQALANTFAALQHGVSTVDASAGGLGGCPYAKSATGNLATEDLVWMLQGLGVDTGVDLGQLTATSVWMAEQLGRPSPSRTVRALSHQES
>CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase
MPLDHRLTPEHEELRRTVEEFAHDVIAPKIGDFYERHEFPYEIVREMGRMGLFGLPFPEEYGGMGGDYLALGIALEELARVDSSVAITLEAGVSLGAMPIFRFGTEEQKRQWLPRLCSGEALGAFGLTEPDCGSDAGGTRTTAVRDGDEWVINGSKCFITNSGTDITGLVTVTAVTGRKDDGRPLISSIIVPSGTPGFTVAAPYSKVGWNASDTRELSFSDVRVPVANLLGEEGRGYAQFLRILDEGRIAISALATGLAQGCVDESVKYAKERHAFGRPIGDNQAIQFKIADMELRAHMARVGWRDAASRLVHGEPFKKEAALAKLYSSTVAVDNAREGTQIFGGYGFMNEYPVARMWRDSKILEIGEGTSEVQRMLIARELGLPA
>CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC
MPHARASLPTRRGLLAMGGAIGIGAALAACGGGDKKSGSADGATGAAKSGPWSFKDDRGQTAQTKAAPKNIVAFTGTAAALFDYGITVKGVFGPTKTKDGNADVQAGSLDISKVEVIGNTYGEFSVEKYAALQPDVLITDMWQKDVLWYVPDNSKDKILKLAPSVALWAADQSMPAALQRRADLAKSLGADLNAKNVTDAKAAFEKASARLRAAAKANPGIKVLLGSASPDLFYVSEAKRSCDTRYFQELGVRFVTPKVDSQGFFESLSWENVGKYPADLILMDNRTGTLQPADLGSKPTWAQLPAVKAHQVVPRLTEPIYSYARVAPIVDALAQAIENAKKVA
>CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB
MPAPAETAIAPFRLFDLRVVRARRLGRSLMRVTFGGFGDEDLSSFAAGGRDQSLSLFLPHPGQEAPVLPPVDDADGWWAAYRALPDGIRAVMRSYTVRAQRRAPLGGPGEIDIDFALHGDGGPASRWARSVRAGGRVTVLGPAVADNTAVRFRPPAGTDSVVIWADETALPAAAGILEWLPSGLPAQVWITAPATPEALPRVTAADARVTWLPSVSPLDAIRSAPLPGASPYVWIAGEASHVRSLRRHFVGERGLERGRVTFVGYWRRGRTEDDLRAA
>CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase
MRAHLLNDTTAEHYRRSVTEGVERVARKLATTRRPFSGVGVDDLAPVIDRIDLDAPLGDTSAVLDELEDVYLRDAVYFHHPRYLAHLNCPVVIPAVLGEAVLSAVNSSLDTWDQSAGGTLIERRLIDWTAGRIGLGPAADGVFTSGGTQSNLQSLLLAREEAKTTDLARLRVFASECSHFSVQKSAQLLGMGRDSVVSIPTDHDKRMQTLALARALERCVSEGNVPMAVVATAGTTDFGSIDPLPGIAELCAQYGAWMHVDAAYGCGLLASPTPARRALLDGIERADSVTVDYHKSFFQPVSSSAVLVRDASTLRHATYHADYLNPRRAAEERIPNQVDKSLQTTRRFDALKLWMTLRTMGADGLGSLFDEVCELAEQGWQLLAADPRYDVVVQPTLSTLVFRYIPATITSPAEIDRANLYARKALFASGEAVVAGTKSGGRQYLKFTLLNPETGVDDIAAVLDLIAGHAEQYLGENLVHAS
>CP032698.1|AYG82722.1|5475040_5476336_-|L-lysine-N6-monooxygenase
MSTRPETPGTGEAYDFIGIGLGPFNLGLACLAEPIEELNGLFLETKPDFEWHSGMFLEGAHLQTPFLSDLVTLADPTSPYSFLNYLKESGRLYSFYIRENFYPLRTEYNDYCRWAAAKLSSVRFNRTVREVTYDESDQTYLVATTTGEAYRARRLVLGTGTPPHLPEPCRGLGGDLLHNSRYLEHREALQKKQSITVVGSGQSAAEIYYDLLSEIDVHGYRLNWVTRSPRFFPLEYTKLTLEMTSPEYIDYFHALPEATRYRLESTQKGLFKGIDSELINAIFDLLYQKSLKGPVPTRLLSNSALTAAGYDTTSGTYTLGLRQEEQEKDYTLSTQGLVLATGYRYAEPEFLAPVSDRLRRDGRGRFDVARNYSIDTTGHGVFLQNAGVHTHSITSPDLGMGAYRNAYIIGELLGREYYRVEKSIAFQEFAI
>CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein
MHQLSRTHAWAHAPDRRYLHVMTDRRAYPSDLSDARWELIEPVLSVWRYERHGRALGFGRPPEHDLREIMNAILYVDRTGVQWRYLPHDFPNWNTVYGYFAKWQSDGIFAQLNGLLRELVRQREGRNAEPSACVIDAQSVKTSTSVPATSQGTDNAKKIVGRKRSIVTDTIGLLIAVLVTAASVQDSVAGTQLLDQVSAEHSSIRKVWVDGGYRQHFVEHAATLGIDMEITARTPGTRGFTPIPKRWAVERTYGWLMLHRRLARDYETRTARSEAMIHLAMTDLMARRLTGESTISWRDPANDNQPPISG
>CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2
MHQALESLLDLLDLERIEEDIFRGRSRSALIPRVFGGQVAAQALVAAGRTVPAERTAHSLHAYFLRAGDPGAPIVYTVDRIRDGASFTTRRVVAIQHGQPIFHLSASFQRYEEGMEHQAAMPPAPDPESLPTAAEMLPRYASAFRDEGVVDRLIEARAAVDLRYVDAPPWASVGTPREPRSQVWFRTNGKLADDPLLHVCLATYVSDMTLLDSVLLAHGRGGWAVGDVVGASLDHAMWFHRPFRADEWLLYDQESPSASGGRGLGQARIYTQDGRLAITVIQEGVVRVPRP
>CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)
MRRTVFNEDHEAFRETLRAFIEAEVVPAYDEWFAQGIVPREFYYKLAELGIFGIRVDEEFGGAGIDSYKFEAVMYEETARAGVQFGGSGVHVLLGLPYIKMLATDEQKKRFLPKFVSGEEMWALAMTEPGTGSDLAGMKTTAKLSEDGTHYVLNGAKTFITGGVHADRVIVCARTDAPSAEDRRHGISLFAVDTKSEGYSVGRKLDKLGLKTSDTAELAFVDVKVPVEDLLGEENKGFYYLGHNLASERWGIAFGAYAQAKAAVRFASEYVRDRTVFGKPVASFQNTKFELAACQAEVDAAEAVADRALEALDAGELTPAEAASAKLFCTEVAHRVIDRCLQLHGGYGFMNEYPIARLYADNRVNRIYGGTSEIMKSIIAKNMGL
>CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein
MPEPTAQPTQPTPPTPPIALAALLARADLGLRQIAGPPDATIRWVHTTEMADPYPYLLGGELLMTAGVQLGDPELYVSRVVAAGAAALGFGVAPVYDAVPPALVEACARHGLPLLEVPPQTTFSGVARAVWLLMARAREDELRRVSEAQRALAAAASRPDPVRGVLRVLAGRLGGWAALMTPEGVVLDAAGGAPSAVVGVGVEGLVRVVSPSADGEDRRPNSAPPAFEERGSGGRAPGAPTGPRPTNAPPEGLGRGRGGENPPKAPAHAHPLTATDTLGDTHLAAYALAETTGTALAIATPHRAPGDHTIAGVAAVLLALLTAGRPGADEAARSAALVRMVLGGAPGDLAALLGEGPWVVVHARGQGAPPDLGTPLVDAAGQTVRALAPADREVTTHPGWTLGVSAPAALDGLAVADLQAARALERAEATRTPLARHRAAGFGALLDPEEAAAYARELLAPLSGPLRATLRTWLSLHGSWDRSAVALGVHRNTVRQRIGRCAALLGTDLDDMDVRTELWLALRSAEAHSGQCR
>CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase
MSSNETPRGPIDSSRIPRYAGPATFARLPRLDEVGTADVAVVGVPFDSGVSYRPGARFGGNAIREASRLLRPYNPAQDASPFALAQVADAGDIAANPFNINEAVETIEAAADDLLGTGARMMTLGGDHTIALPLLRSVAKKHGPVALLHFDAHLDTWDTYFGAEYTHGTPFRRAVEEGILDTEALSHVGTRGPLYGKQDLTDDEKMGFGIVTSADVYRRGADEVADQLRQRIGDRPLYISIDIDCLDPAHAPGTGTPEAGGMTSRELLEILRGLASCNLVSADVVEVAPAYDHAEITSVAASHTAYELTTIMSRQIAASRA
>CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit
MTHDHDIVLRPTAAQTAAALNPPPGRIGGDLVVETLAGLGATTVFGLPGQHALGMFDALRRSDLTYVGLRVENNAGFAADAYGRITGEAAPLLLSTGPGALTSLAALQEAAAASSPVIALSSQVPTAGVGGGRHGYLHELRDQQASFRDVVKSVHVVRAPSQIPSAIAAAWESALTAPHGPVWVEIPEDVLLAETVLPVVTPMDAFPEEIVPRPELTAVAAELLATAERPAIIAGGGVVRSDASGKLRALAERLDAPVVTTFGGKGAFPWEHPLSLQSWLEDRHTTDFLEDADVLLVVGSGLGELSSNYHTFKPRGRIVQIEADLGKLESNHPALGIHADARTALQALLETVPERTDPTAAERVRTLLDKVRARLDAQDLGEERRILAAVREALPAGAPSFWDMTILTYWAWSAWPGAMHSAQGAGGLGYGFPAALGAAVADPSGPVLAVSGDGGAMYSIAELATAKQYGLPVTWLIVDDGGYGILRAYMTDAFGEATATATELARPDFVALAESFGVPAVRTTPDTLAADLAKALAEPGPSVVVLSAVLRMFEPTHR
>CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein
MTEGAQQGWARRLTGYAWRYRRNVALSLGSSLAGMAVMALVPLITKVVIDDVIGAHTRSLAVWTGLLIASAVVVYALTYIRRYYGGRLALDVQHDLRTEMYRTITRLDGRRQDELSTGQVVGRATSDLQLIQGLLFMLPMTIGNVLLFVISVVIMAWLSPLLTLVALAVAPALWFIAKRSRTRLFPATWYAQGQAAAVAGVVDGAVSGVRVVKGFGQEDQETGKLREVGRRLFAGRMRTIKLNSRYTPALQAVPALGQVAMLALGGWLATRGEITLGTFVAFSTYLAQLVGPVRMLAMVLTVGQQARAGVERVLELIDTEPSLQDGTKELSPSAPATVEFDDVSFGYDDERPVLDGFSLDIRPGETVAVVGASGSGKSTVSMLLPRFYDVSHGAVLVGGHDVRELTLSSLRAAIGLVPEDSFLFSDTVRANIAYGKPDATQDEIEKATRAAQAHGFISELPKGYDTTVGEHGLTLSGGQRQRIALARAILTDPRLLVLDDATSAVDARVEHEIHEALASVMAGRTTLLIAHRRSTLGLADRIAVLDAGRLAAIGTHEELQRDSALYRRLLTDPDELGAVSPGHTPTAPAVEEEDHSVRDELDAEFDAERGITPPLWVREEKPESAAPGGMPATPELLAQVEALPPATDTPDIDEARAVQPEDSYGLRRLLRGFGLPLLVSLLLVAIDAGMSLLLPVLIRHGIDQGVSKLALGAVWAAAGLALLTVVIQWLAQTGETRMTGRTGERVLYTLRLKIFAQLQRLGLDYYERELTGRIMTRMTTDVDALATFLQTGLVTAFVSVVTFFGIMVALLVIDLQLALVVFATLPLLVVGTYFFRKKSVQAYELARERVGVVNADLQESVSGLRIVQAFRREHDGARRFAERSDHYRQARVRGQWLISVYFPFVQLLSSVAAAAVLIVGAGRVDHGTLTAGALVAYLLYIDLFFAPVQQLSQVFDGYQQASVSLGRIQELLQEKTSTSEAAAPLDVLSLRGEIAFENVDFAYGSADGSGDEPEEALSGVDLRIPAGQTVAFVGETGAGKSTLVKLVARFYDPTGGRVTADGTDLRDLDITAYRHRLGVVPQEAYLFPGTVRDAIAYGRPGASDAEVEAAARAVGAHDMIATLDGGYLHEVAERGRNLSAGQRQLIALARAELVDPDVLLLDEATAALDLATEAQVNQATERLTGRRTTLVVAHRLTTAARADRVVVMDQGRVVEDGTHAELLALDGKYARLWHTFTSTPEPTPTPG
>CP032698.1|AYG82739.1|5501081_5501468_+|hypothetical-protein
MFGGMKRNPAPTLAVLAATGSLLMFGPPSGSADAAAACAGRPVKTVGFSTGELRLYKGNGYACAVTEAKSPGPRRQMSVTIQARGGAPAGDSGAYTQRAGPVTVHVGNRCVRATGSISGSSAETGWVC
>CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase
MRKALRWLLSLVVLTGTIAATGATAGAATAAEPDIKDRILAIPGVSLIAEKPYNGYRYFVLSFTQPVDHHNPYRRATFQQRITVLHKDTARPTVMYTSGYEVSTNPGRSEPTAIVDGNQVSVEYRFFPESRPTPTDWSKDDIWQAASDQHAIFQALKPVYSKNWLTTGGSKGGMTATYYKRFYPRDMDGVVAYVAPNDVVNNEDSAYDRFFRTVGTKECRDKLEGVQRQALVRRESLEKKYQEYAAANGYTFATVGTLDKAYEAVVLDYVWGFWQYHLLAECDTLPADPAHASDQAIWDSVDTISGFSFYTDQGLAPYTAYYYQAGTQLGSPTIKQPWLGNLSRYGYQPPRNFVPRDIPMRFQPWAMRDVDSWVKHHADHMLYVYGQNDPWGAERFSLGAGARDSYVYTVAGGNHGSKVAQLPADQKAAATASILRWAGVGAGAVRAPFDAKLDATPTTREPTLHP
>CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase
MQHRTSRRSLLTSTAATAVLAALGLPLPAHALDAPAAAGRDRGLRALIARMSVEEKIGQLFVMRVYGHSATAPDQADIDANLRELGVRDAAELIARYHVGGIIYFSWAHNTRDPHQIAELSNGIQAAGLAQRVPLPLLIATDQEHGAVCRVGKPVTLFPGAMAMGAGGSARDARTLGRISGAELAAIGIRQDYSPDADVNVNPANPVIGVRSFGADPAAVARMVAAEVRGYQESSVAATAKHFPGHGDTTVDSHTGIPVINHSRAEWERLDAPPFRAAIAAGIDAIMTAHIQFPALDPSNDPATLSRPILTGILREELGFDGVVITDSLGMQGVRDKYGDDRVPVLALKAGVDQLLDPPRLDVAFNGVRAAVASGELSEARLDASLLRILRLKERRGLFARPYVSVRGVGRTVGTRAHLRAADEIAERTTTLLANPRGLLPLSRRSHRRLLIVGADPASPSGTTGPPTSVLAAALAELGFQTTVLPTGTLPSAAQIEAAVAAAVGRDAVIVGTYNAGAGGAQSRLVAALGASGVPVVHLALRNPYDVAYLSGYGASLATYSWTDVELRAAVRVLTGRARPRGHLPVAVPRPDDPASPLYPVGYGLTY

Crispr_ID: CP032698_70

• CRISPR_ID: CP032698_70
• CRISPR_location: 5488528-5488677
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_70

Consensus_repeat	Method
TTAAGGGGCGCGGGGAACTGCGCGCCCAGCCACGCACG	PILER-CR

spacers of CP032698_70

>70.1|5488566|21|CP032698|PILER-CR
ACCCGCAGACGAAAACGGGTT
>70.2|5488625|32|CP032698|PILER-CR
AGAAGCGACCACGGCCCGCAGGGTCGAGAGGG

CRISPR arrays and Neighbor proteins around CP032698_70

CRISPR arrays

The CRISPR arrays of CP032698_70

>merge|CP032698|70|5488528-5488677|PILER-CR
AGGGGCGCGGGGAACTGCGCGCCCAGCCACGCACGACCCGCAGACGAAAACGGGTTTTAAGGGGCGCGGGGAACTGCGCGAGAAGCGACCACGGCCCGCAGGGTCGAGAGGGTTTAGGGGCGCGGGGAACTGCGCGCCCAGCCACGCACG

>CP032698|70|19|5488528-5488677|PILER-CR
AGGGGCGCGGGGAACTGCGCGCCCAGCCACGCACGACC	CGCAGACGAAAACGGGTTTTA
AGGGGCGCGGGGAACTGCGCGAGAAGCGACCACGGCCC	GCAGGGTCGAGAGGGTTTAGGGGCGCGGGGAA
CTGCGCGCCCAGCCACGCACG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase	unknown	unknown	gnl|CDD|283275
CP032698.1|AYG82722.1|5475040_5476336_-|L-lysine-N6-monooxygenase	unknown	unknown	gnl|CDD|226017
CP032698.1|AYG82739.1|5501081_5501468_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)	unknown	unknown	gnl|CDD|173849
CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase	unknown	unknown	gnl|CDD|212538
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain	unknown	unknown	gnl|CDD|227111
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	unknown	unknown	gnl|CDD|224857
CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit	unknown	unknown	gnl|CDD|178415
CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein	unknown	unknown	gnl|CDD|224055
CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase	unknown	unknown	gnl|CDD|366376
CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|223107
CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein	unknown	unknown	gnl|CDD|377939
CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase	unknown	unknown	gnl|CDD|99743
CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG	unknown	unknown	gnl|CDD|163676
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	unknown	unknown	gnl|CDD|374030
CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB	unknown	unknown	gnl|CDD|99790
CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC	unknown	unknown	gnl|CDD|223687

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase	gnl|CDD|283275	pfam05576, Peptidase_S37, PS-10 peptidase S37. These serine proteases have been found in Streptomyces species.	0
CP032698.1|AYG82722.1|5475040_5476336_-|L-lysine-N6-monooxygenase	gnl|CDD|226017	COG3486, IucD, Lysine/ornithine N-monooxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	0
CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase	gnl|CDD|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	2.75366e-125
CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	3.09476e-168
CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)	gnl|CDD|173849	cd01160, LCAD, Long chain acyl-CoA dehydrogenase. LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer.	4.61967e-145
CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase	gnl|CDD|212538	cd11592, Agmatinase_PAH, Agmatinase-like family includes proclavaminic acid amidinohydrolase. This agmatinase subfamily contains bacterial and fungal/metazoan enzymes, including proclavaminic acid amidinohydrolase (PAH, EC 3.5.3.22) and Pseudomonas aeruginosa guanidinobutyrase (GbuA) and guanidinopropionase (GpuA). PAH hydrolyzes amidinoproclavaminate to yield proclavaminate and urea in clavulanic acid biosynthesis. Clavulanic acid is an effective inhibitor of beta-lactamases and is used in combination with amoxicillin to prevent the beta-lactam rings of the antibiotic from hydrolysis and, thus keeping the antibiotic biologically active. GbuA hydrolyzes 4-guanidinobutyrate (4-GB) into 4-aminobutyrate and urea while GpuA hydrolyzes 3-guanidinopropionate (3-GP) into beta-alanine and urea. Mutation studies show that significant variations in two active site loops in these two enzymes may be important for substrate specificity. This subfamily belongs to the ureohydrolase superfamily, which includes arginase, agmatinase, proclavaminate amidinohydrolase, and formiminoglutamase.	6.02255e-167
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	5.70484e-31
CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	gnl|CDD|224857	COG1946, TesB, Acyl-CoA thioesterase [Lipid metabolism].	6.5483e-122
CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit	gnl|CDD|178415	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain.	0
CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.1722e-168
CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.62199e-13
CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit	gnl|CDD|223107	COG0028, IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism].	6.88462e-137
CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein	gnl|CDD|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	3.65701e-23
CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase	gnl|CDD|99743	cd06450, DOPA_deC_like, DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.	5.02668e-121
CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG	gnl|CDD|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	9.59339e-157
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	gnl|CDD|374030	pfam15698, Phosphatase, Phosphatase. Members of this family have phosphatase activity.	1.42957e-133
CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB	gnl|CDD|99790	cd06193, siderophore_interacting, Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from transferrin and lactoferrin for bacterial uptake, contributing to pathogen virulence. Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport mechanism of photosystem I. FNR transfers electrons from reduced ferredoxin to FAD (forming FADH2 via a semiquinone intermediate) and then transfers a hydride ion to convert NADP+ to NADPH. FNR has since been shown to utilize a variety of electron acceptors and donors and has a variety of physiological functions including nitrogen assimilation, dinitrogen fixation, steroid hydroxylation, fatty acid metabolism, oxygenase activity, and methane assimilation in a variety of organisms. FNR has an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) flavin sub-domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal moeity may contain a flavin prosthetic group (as in flavoenzymes) or use flavin as a substrate. Because flavins such as FAD can exist in oxidized, semiquinone (one-electron reduced), or fully reduced hydroquinone forms, FNR can interact with one and two electron carriers. FNR has a strong preference for NADP(H) vs NAD(H).	4.55184e-62
CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC	gnl|CDD|223687	COG0614, FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism].	9.11851e-20

Protein sequences

>CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase
MGNMPIPSRAALVDHLVRTRIAGDVATPRDNNLSHYRRLANGDRHYWLGLELGDRWTDEQDVLAVMAERCGVVDDPGHRTGQDTIDPELTVDGLERMAARLRKAAAGRERVLFATGHPGALIDVHSRTAAALRSAGCDIVRIPGGLTADEGYVVQFADVAVFERGASLWHTHSPEPMRAILDALETPPDLVVADHGWAGCAGQRGVDAVGYADSNDPALFLAEAEGTLQVTVPLDDHVVDPRFYEPMTAYLLDAAGLS
>CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R
MSTRTDAPTRREQILREAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFAGKDAMLAELLVGISGRLYDGGRKRVAEAAGDPERLLGALIDGHIDFALDDRALITLHDRELDRLRDSDRKLVRQLQRQYVELWVGVVRELYPAVAEAEVRGAVHAVFGLLNSTPHLGSYGSGLPGRAATETLLRRLAHGAFASLAPLAGR
>CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit
MQQAPVLGSAADPASAAWRANEAAHRTLGEELRARLAAARLGGGERSRQRHVARGKLLPRDRVDTLLDPGSPFLELAPLAAEGMYGGQAPAAGVIAGIGRVSGRECVIVANDATVKGGTYYPMTVKKHLRAQEVALENRLPCLYLVDSGGAFLPMQDEVFPDRDHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLVKAATGEVVTAEELGGGEVHAKVSGVTDHLAEDDAHALRIVRNIVATLPERGPLPWSVEPAEEPKADPFGLYGAVPVDSRTPYDVREVIARVVDGSRFQEFKSEFGQTLVTGFARIHGHPVGIVANNGILFSESAQKGAHFIELCDQRGLPLVFLQNISGFMVGRDYEAGGIAKHGAKMVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMGGEQAASVLATVKRDQLGDDWSAEDEEAFKAPIREQYETQGNAYYATARLWDDGVIDPVDTRQVLGLALTACANAPLTDPAFGVFRM
>CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain
MFTTVLVANRGEIAVRVIRTLRQLGIRSVAVFSDADAEARHVREADTAVRIGPAAASESYLRPELLIEAARRTGAQAVHPGYGFLAENAGFAQACAEAGLVFIGPPAEAISLMGDKIRAKETVQKAGVPVVPGSSGSGLSDAQLADAAREIGMPVLLKPSAGGGGKGMRLVREEALLGDEIAAARREARASFGDDTLLVERWIDRPRHIEIQVLADNHGHVIHLGERECSLQRRHQKIIEEAPSVLLDEATRAAMGEAAVQAARSCGYSGAGTVEFIVPGSDPSSYYFMEMNTRLQVEHPVTELITGVDLVEWQLRVAAGEQLPYEQKDITLTGHAIEARLCAEDPSRGFLPSGGTVLALREPQGDGVRTDSGLSEGTEVGSLYDPMLSKVIAYGPDRATALRKLRAALADTVTLCVPTNAGFLRRLLAHPAVVAGELDTGLVEREADSLVPDGVPEEVYAAAAAVRLDALRPAPTDGWTDPFAVPSGWRMGGEPKALAFPLRVSGLEPVTHPAPTTARVTADRVTVELDGLTHTFHRAGAWLGRDGDSWHVTDHDAVEAALSGRTHGGADTLAAPMPGTVTVVKVAVGDQVDAGQSLLVVEAMKMEHVISAPHAGTVTELDVTPGSTVAMDQVLAVVTPAVQESPQDSSQDSSQKSLEESS
>CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG
MTDLPMVVPAEGLPARVRIHEVGARDGLQNEKTVVPTEVKAEFVHRLAAAGLTTVEATSFVHPKWVPQLADAEALFPMLGDLDGVALPVLVPNERGLDRALALGATRIAVFASATESFAKANLNRTVDESLAMFEPVVARAKADGAHVRGYLSMCFGDPWEGAVPVAQVVRVAKALMELGCDELSLGDTIGVATPAHVGALLTGLNDRSIATDAIGVHFHDTYGQALANTFAALQHGVSTVDASAGGLGGCPYAKSATGNLATEDLVWMLQGLGVDTGVDLGQLTATSVWMAEQLGRPSPSRTVRALSHQES
>CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase
MPLDHRLTPEHEELRRTVEEFAHDVIAPKIGDFYERHEFPYEIVREMGRMGLFGLPFPEEYGGMGGDYLALGIALEELARVDSSVAITLEAGVSLGAMPIFRFGTEEQKRQWLPRLCSGEALGAFGLTEPDCGSDAGGTRTTAVRDGDEWVINGSKCFITNSGTDITGLVTVTAVTGRKDDGRPLISSIIVPSGTPGFTVAAPYSKVGWNASDTRELSFSDVRVPVANLLGEEGRGYAQFLRILDEGRIAISALATGLAQGCVDESVKYAKERHAFGRPIGDNQAIQFKIADMELRAHMARVGWRDAASRLVHGEPFKKEAALAKLYSSTVAVDNAREGTQIFGGYGFMNEYPVARMWRDSKILEIGEGTSEVQRMLIARELGLPA
>CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC
MPHARASLPTRRGLLAMGGAIGIGAALAACGGGDKKSGSADGATGAAKSGPWSFKDDRGQTAQTKAAPKNIVAFTGTAAALFDYGITVKGVFGPTKTKDGNADVQAGSLDISKVEVIGNTYGEFSVEKYAALQPDVLITDMWQKDVLWYVPDNSKDKILKLAPSVALWAADQSMPAALQRRADLAKSLGADLNAKNVTDAKAAFEKASARLRAAAKANPGIKVLLGSASPDLFYVSEAKRSCDTRYFQELGVRFVTPKVDSQGFFESLSWENVGKYPADLILMDNRTGTLQPADLGSKPTWAQLPAVKAHQVVPRLTEPIYSYARVAPIVDALAQAIENAKKVA
>CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB
MPAPAETAIAPFRLFDLRVVRARRLGRSLMRVTFGGFGDEDLSSFAAGGRDQSLSLFLPHPGQEAPVLPPVDDADGWWAAYRALPDGIRAVMRSYTVRAQRRAPLGGPGEIDIDFALHGDGGPASRWARSVRAGGRVTVLGPAVADNTAVRFRPPAGTDSVVIWADETALPAAAGILEWLPSGLPAQVWITAPATPEALPRVTAADARVTWLPSVSPLDAIRSAPLPGASPYVWIAGEASHVRSLRRHFVGERGLERGRVTFVGYWRRGRTEDDLRAA
>CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase
MRAHLLNDTTAEHYRRSVTEGVERVARKLATTRRPFSGVGVDDLAPVIDRIDLDAPLGDTSAVLDELEDVYLRDAVYFHHPRYLAHLNCPVVIPAVLGEAVLSAVNSSLDTWDQSAGGTLIERRLIDWTAGRIGLGPAADGVFTSGGTQSNLQSLLLAREEAKTTDLARLRVFASECSHFSVQKSAQLLGMGRDSVVSIPTDHDKRMQTLALARALERCVSEGNVPMAVVATAGTTDFGSIDPLPGIAELCAQYGAWMHVDAAYGCGLLASPTPARRALLDGIERADSVTVDYHKSFFQPVSSSAVLVRDASTLRHATYHADYLNPRRAAEERIPNQVDKSLQTTRRFDALKLWMTLRTMGADGLGSLFDEVCELAEQGWQLLAADPRYDVVVQPTLSTLVFRYIPATITSPAEIDRANLYARKALFASGEAVVAGTKSGGRQYLKFTLLNPETGVDDIAAVLDLIAGHAEQYLGENLVHAS
>CP032698.1|AYG82722.1|5475040_5476336_-|L-lysine-N6-monooxygenase
MSTRPETPGTGEAYDFIGIGLGPFNLGLACLAEPIEELNGLFLETKPDFEWHSGMFLEGAHLQTPFLSDLVTLADPTSPYSFLNYLKESGRLYSFYIRENFYPLRTEYNDYCRWAAAKLSSVRFNRTVREVTYDESDQTYLVATTTGEAYRARRLVLGTGTPPHLPEPCRGLGGDLLHNSRYLEHREALQKKQSITVVGSGQSAAEIYYDLLSEIDVHGYRLNWVTRSPRFFPLEYTKLTLEMTSPEYIDYFHALPEATRYRLESTQKGLFKGIDSELINAIFDLLYQKSLKGPVPTRLLSNSALTAAGYDTTSGTYTLGLRQEEQEKDYTLSTQGLVLATGYRYAEPEFLAPVSDRLRRDGRGRFDVARNYSIDTTGHGVFLQNAGVHTHSITSPDLGMGAYRNAYIIGELLGREYYRVEKSIAFQEFAI
>CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein
MHQLSRTHAWAHAPDRRYLHVMTDRRAYPSDLSDARWELIEPVLSVWRYERHGRALGFGRPPEHDLREIMNAILYVDRTGVQWRYLPHDFPNWNTVYGYFAKWQSDGIFAQLNGLLRELVRQREGRNAEPSACVIDAQSVKTSTSVPATSQGTDNAKKIVGRKRSIVTDTIGLLIAVLVTAASVQDSVAGTQLLDQVSAEHSSIRKVWVDGGYRQHFVEHAATLGIDMEITARTPGTRGFTPIPKRWAVERTYGWLMLHRRLARDYETRTARSEAMIHLAMTDLMARRLTGESTISWRDPANDNQPPISG
>CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2
MHQALESLLDLLDLERIEEDIFRGRSRSALIPRVFGGQVAAQALVAAGRTVPAERTAHSLHAYFLRAGDPGAPIVYTVDRIRDGASFTTRRVVAIQHGQPIFHLSASFQRYEEGMEHQAAMPPAPDPESLPTAAEMLPRYASAFRDEGVVDRLIEARAAVDLRYVDAPPWASVGTPREPRSQVWFRTNGKLADDPLLHVCLATYVSDMTLLDSVLLAHGRGGWAVGDVVGASLDHAMWFHRPFRADEWLLYDQESPSASGGRGLGQARIYTQDGRLAITVIQEGVVRVPRP
>CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)
MRRTVFNEDHEAFRETLRAFIEAEVVPAYDEWFAQGIVPREFYYKLAELGIFGIRVDEEFGGAGIDSYKFEAVMYEETARAGVQFGGSGVHVLLGLPYIKMLATDEQKKRFLPKFVSGEEMWALAMTEPGTGSDLAGMKTTAKLSEDGTHYVLNGAKTFITGGVHADRVIVCARTDAPSAEDRRHGISLFAVDTKSEGYSVGRKLDKLGLKTSDTAELAFVDVKVPVEDLLGEENKGFYYLGHNLASERWGIAFGAYAQAKAAVRFASEYVRDRTVFGKPVASFQNTKFELAACQAEVDAAEAVADRALEALDAGELTPAEAASAKLFCTEVAHRVIDRCLQLHGGYGFMNEYPIARLYADNRVNRIYGGTSEIMKSIIAKNMGL
>CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein
MPEPTAQPTQPTPPTPPIALAALLARADLGLRQIAGPPDATIRWVHTTEMADPYPYLLGGELLMTAGVQLGDPELYVSRVVAAGAAALGFGVAPVYDAVPPALVEACARHGLPLLEVPPQTTFSGVARAVWLLMARAREDELRRVSEAQRALAAAASRPDPVRGVLRVLAGRLGGWAALMTPEGVVLDAAGGAPSAVVGVGVEGLVRVVSPSADGEDRRPNSAPPAFEERGSGGRAPGAPTGPRPTNAPPEGLGRGRGGENPPKAPAHAHPLTATDTLGDTHLAAYALAETTGTALAIATPHRAPGDHTIAGVAAVLLALLTAGRPGADEAARSAALVRMVLGGAPGDLAALLGEGPWVVVHARGQGAPPDLGTPLVDAAGQTVRALAPADREVTTHPGWTLGVSAPAALDGLAVADLQAARALERAEATRTPLARHRAAGFGALLDPEEAAAYARELLAPLSGPLRATLRTWLSLHGSWDRSAVALGVHRNTVRQRIGRCAALLGTDLDDMDVRTELWLALRSAEAHSGQCR
>CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase
MSSNETPRGPIDSSRIPRYAGPATFARLPRLDEVGTADVAVVGVPFDSGVSYRPGARFGGNAIREASRLLRPYNPAQDASPFALAQVADAGDIAANPFNINEAVETIEAAADDLLGTGARMMTLGGDHTIALPLLRSVAKKHGPVALLHFDAHLDTWDTYFGAEYTHGTPFRRAVEEGILDTEALSHVGTRGPLYGKQDLTDDEKMGFGIVTSADVYRRGADEVADQLRQRIGDRPLYISIDIDCLDPAHAPGTGTPEAGGMTSRELLEILRGLASCNLVSADVVEVAPAYDHAEITSVAASHTAYELTTIMSRQIAASRA
>CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit
MTHDHDIVLRPTAAQTAAALNPPPGRIGGDLVVETLAGLGATTVFGLPGQHALGMFDALRRSDLTYVGLRVENNAGFAADAYGRITGEAAPLLLSTGPGALTSLAALQEAAAASSPVIALSSQVPTAGVGGGRHGYLHELRDQQASFRDVVKSVHVVRAPSQIPSAIAAAWESALTAPHGPVWVEIPEDVLLAETVLPVVTPMDAFPEEIVPRPELTAVAAELLATAERPAIIAGGGVVRSDASGKLRALAERLDAPVVTTFGGKGAFPWEHPLSLQSWLEDRHTTDFLEDADVLLVVGSGLGELSSNYHTFKPRGRIVQIEADLGKLESNHPALGIHADARTALQALLETVPERTDPTAAERVRTLLDKVRARLDAQDLGEERRILAAVREALPAGAPSFWDMTILTYWAWSAWPGAMHSAQGAGGLGYGFPAALGAAVADPSGPVLAVSGDGGAMYSIAELATAKQYGLPVTWLIVDDGGYGILRAYMTDAFGEATATATELARPDFVALAESFGVPAVRTTPDTLAADLAKALAEPGPSVVVLSAVLRMFEPTHR
>CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein
MTEGAQQGWARRLTGYAWRYRRNVALSLGSSLAGMAVMALVPLITKVVIDDVIGAHTRSLAVWTGLLIASAVVVYALTYIRRYYGGRLALDVQHDLRTEMYRTITRLDGRRQDELSTGQVVGRATSDLQLIQGLLFMLPMTIGNVLLFVISVVIMAWLSPLLTLVALAVAPALWFIAKRSRTRLFPATWYAQGQAAAVAGVVDGAVSGVRVVKGFGQEDQETGKLREVGRRLFAGRMRTIKLNSRYTPALQAVPALGQVAMLALGGWLATRGEITLGTFVAFSTYLAQLVGPVRMLAMVLTVGQQARAGVERVLELIDTEPSLQDGTKELSPSAPATVEFDDVSFGYDDERPVLDGFSLDIRPGETVAVVGASGSGKSTVSMLLPRFYDVSHGAVLVGGHDVRELTLSSLRAAIGLVPEDSFLFSDTVRANIAYGKPDATQDEIEKATRAAQAHGFISELPKGYDTTVGEHGLTLSGGQRQRIALARAILTDPRLLVLDDATSAVDARVEHEIHEALASVMAGRTTLLIAHRRSTLGLADRIAVLDAGRLAAIGTHEELQRDSALYRRLLTDPDELGAVSPGHTPTAPAVEEEDHSVRDELDAEFDAERGITPPLWVREEKPESAAPGGMPATPELLAQVEALPPATDTPDIDEARAVQPEDSYGLRRLLRGFGLPLLVSLLLVAIDAGMSLLLPVLIRHGIDQGVSKLALGAVWAAAGLALLTVVIQWLAQTGETRMTGRTGERVLYTLRLKIFAQLQRLGLDYYERELTGRIMTRMTTDVDALATFLQTGLVTAFVSVVTFFGIMVALLVIDLQLALVVFATLPLLVVGTYFFRKKSVQAYELARERVGVVNADLQESVSGLRIVQAFRREHDGARRFAERSDHYRQARVRGQWLISVYFPFVQLLSSVAAAAVLIVGAGRVDHGTLTAGALVAYLLYIDLFFAPVQQLSQVFDGYQQASVSLGRIQELLQEKTSTSEAAAPLDVLSLRGEIAFENVDFAYGSADGSGDEPEEALSGVDLRIPAGQTVAFVGETGAGKSTLVKLVARFYDPTGGRVTADGTDLRDLDITAYRHRLGVVPQEAYLFPGTVRDAIAYGRPGASDAEVEAAARAVGAHDMIATLDGGYLHEVAERGRNLSAGQRQLIALARAELVDPDVLLLDEATAALDLATEAQVNQATERLTGRRTTLVVAHRLTTAARADRVVVMDQGRVVEDGTHAELLALDGKYARLWHTFTSTPEPTPTPG
>CP032698.1|AYG82739.1|5501081_5501468_+|hypothetical-protein
MFGGMKRNPAPTLAVLAATGSLLMFGPPSGSADAAAACAGRPVKTVGFSTGELRLYKGNGYACAVTEAKSPGPRRQMSVTIQARGGAPAGDSGAYTQRAGPVTVHVGNRCVRATGSISGSSAETGWVC
>CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase
MRKALRWLLSLVVLTGTIAATGATAGAATAAEPDIKDRILAIPGVSLIAEKPYNGYRYFVLSFTQPVDHHNPYRRATFQQRITVLHKDTARPTVMYTSGYEVSTNPGRSEPTAIVDGNQVSVEYRFFPESRPTPTDWSKDDIWQAASDQHAIFQALKPVYSKNWLTTGGSKGGMTATYYKRFYPRDMDGVVAYVAPNDVVNNEDSAYDRFFRTVGTKECRDKLEGVQRQALVRRESLEKKYQEYAAANGYTFATVGTLDKAYEAVVLDYVWGFWQYHLLAECDTLPADPAHASDQAIWDSVDTISGFSFYTDQGLAPYTAYYYQAGTQLGSPTIKQPWLGNLSRYGYQPPRNFVPRDIPMRFQPWAMRDVDSWVKHHADHMLYVYGQNDPWGAERFSLGAGARDSYVYTVAGGNHGSKVAQLPADQKAAATASILRWAGVGAGAVRAPFDAKLDATPTTREPTLHP
>CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase
MQHRTSRRSLLTSTAATAVLAALGLPLPAHALDAPAAAGRDRGLRALIARMSVEEKIGQLFVMRVYGHSATAPDQADIDANLRELGVRDAAELIARYHVGGIIYFSWAHNTRDPHQIAELSNGIQAAGLAQRVPLPLLIATDQEHGAVCRVGKPVTLFPGAMAMGAGGSARDARTLGRISGAELAAIGIRQDYSPDADVNVNPANPVIGVRSFGADPAAVARMVAAEVRGYQESSVAATAKHFPGHGDTTVDSHTGIPVINHSRAEWERLDAPPFRAAIAAGIDAIMTAHIQFPALDPSNDPATLSRPILTGILREELGFDGVVITDSLGMQGVRDKYGDDRVPVLALKAGVDQLLDPPRLDVAFNGVRAAVASGELSEARLDASLLRILRLKERRGLFARPYVSVRGVGRTVGTRAHLRAADEIAERTTTLLANPRGLLPLSRRSHRRLLIVGADPASPSGTTGPPTSVLAAALAELGFQTTVLPTGTLPSAAQIEAAVAAAVGRDAVIVGTYNAGAGGAQSRLVAALGASGVPVVHLALRNPYDVAYLSGYGASLATYSWTDVELRAAVRVLTGRARPRGHLPVAVPRPDDPASPLYPVGYGLTY

Crispr_ID: CP032698_71

• CRISPR_ID: CP032698_71
• CRISPR_location: 5489828-5490078
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP032698_71

Consensus_repeat	Method
AGGGGCGCGGGGAACTGCGCGA	CRT

spacers of CP032698_71

>71.1|5489850|34|CP032698|CRT
GAAGCGACCACGGCCCGCAGGGTCGGGAGGGTTT
>71.2|5489906|37|CP032698|CRT
CCAGCCACCCGCGGTCCGCAGACGAAAGCGGGTTTTC
>71.3|5489965|34|CP032698|CRT
GAAGCGACCACGACCCGCAGGTTCGAGTGGGTTT
>71.4|5490021|36|CP032698|CRT
CCAGCCATCTGCGGCCCGCAGACGACAACGGGTTTT

CRISPR arrays and Neighbor proteins around CP032698_71

CRISPR arrays

The CRISPR arrays of CP032698_71

>merge|CP032698|71|5489828-5490078|CRT
AGGGGCGCGGGGAACTGCGCGAGAAGCGACCACGGCCCGCAGGGTCGGGAGGGTTTAGGGGCGCGGGGAACTGCGCGACCAGCCACCCGCGGTCCGCAGACGAAAGCGGGTTTTCAGGGGCGCGAGGAACTGCGCGAGAAGCGACCACGACCCGCAGGTTCGAGTGGGTTTAGGGGCGCGGGGAACTGCGCGACCAGCCATCTGCGGCCCGCAGACGACAACGGGTTTTAGGGGCGCGGGGAACTGCGCGG

>CP032698|71|9|5489828-5490078|CRT
AGGGGCGCGGGGAACTGCGCGA	GAAGCGACCACGGCCCGCAGGGTCGGGAGGGTTT
AGGGGCGCGGGGAACTGCGCGA	CCAGCCACCCGCGGTCCGCAGACGAAAGCGGGTTTTC
AGGGGCGCGAGGAACTGCGCGA	GAAGCGACCACGACCCGCAGGTTCGAGTGGGTTT
AGGGGCGCGGGGAACTGCGCGA	CCAGCCATCTGCGGCCCGCAGACGACAACGGGTTTT
AGGGGCGCGGGGAACTGCGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase	unknown	unknown	gnl|CDD|283275
CP032698.1|AYG82742.1|5505563_5506232_-|hypothetical-protein	unknown	unknown	gnl|CDD|187555
CP032698.1|AYG82739.1|5501081_5501468_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173847
CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)	unknown	unknown	gnl|CDD|173849
CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase	unknown	unknown	gnl|CDD|212538
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain	unknown	unknown	gnl|CDD|227111
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	unknown	unknown	gnl|CDD|224857
CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit	unknown	unknown	gnl|CDD|178415
CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein	unknown	unknown	gnl|CDD|224055
CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase	unknown	unknown	gnl|CDD|99743
CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase	unknown	unknown	gnl|CDD|366376
CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|223107
CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein	unknown	unknown	gnl|CDD|377939
CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG	unknown	unknown	gnl|CDD|163676
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	unknown	unknown	gnl|CDD|374030
CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB	unknown	unknown	gnl|CDD|99790
CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC	unknown	unknown	gnl|CDD|223687

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase	gnl|CDD|283275	pfam05576, Peptidase_S37, PS-10 peptidase S37. These serine proteases have been found in Streptomyces species.	0
CP032698.1|AYG82742.1|5505563_5506232_-|hypothetical-protein	gnl|CDD|187555	cd05244, BVR-B_like_SDR_a, biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs. Human BVR-B catalyzes pyridine nucleotide-dependent production of bilirubin-IX beta during fetal development; in the adult BVR-B has flavin and ferric reductase activities. Human BVR-B catalyzes the reduction of FMN, FAD, and riboflavin. Recognition of flavin occurs mostly by hydrophobic interactions, accounting for the broad substrate specificity. Atypical SDRs are distinct from classical SDRs. BVR-B does not share the key catalytic triad, or conserved tyrosine typical of SDRs. The glycine-rich NADP-binding motif of BVR-B is GXXGXXG, which is similar but not identical to the pattern seen in extended SDRs. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.85152e-51
CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase	gnl|CDD|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	2.75366e-125
CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase	gnl|CDD|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	3.09476e-168
CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)	gnl|CDD|173849	cd01160, LCAD, Long chain acyl-CoA dehydrogenase. LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer.	4.61967e-145
CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase	gnl|CDD|212538	cd11592, Agmatinase_PAH, Agmatinase-like family includes proclavaminic acid amidinohydrolase. This agmatinase subfamily contains bacterial and fungal/metazoan enzymes, including proclavaminic acid amidinohydrolase (PAH, EC 3.5.3.22) and Pseudomonas aeruginosa guanidinobutyrase (GbuA) and guanidinopropionase (GpuA). PAH hydrolyzes amidinoproclavaminate to yield proclavaminate and urea in clavulanic acid biosynthesis. Clavulanic acid is an effective inhibitor of beta-lactamases and is used in combination with amoxicillin to prevent the beta-lactam rings of the antibiotic from hydrolysis and, thus keeping the antibiotic biologically active. GbuA hydrolyzes 4-guanidinobutyrate (4-GB) into 4-aminobutyrate and urea while GpuA hydrolyzes 3-guanidinopropionate (3-GP) into beta-alanine and urea. Mutation studies show that significant variations in two active site loops in these two enzymes may be important for substrate specificity. This subfamily belongs to the ureohydrolase superfamily, which includes arginase, agmatinase, proclavaminate amidinohydrolase, and formiminoglutamase.	6.02255e-167
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	5.70484e-31
CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain	gnl|CDD|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	gnl|CDD|224857	COG1946, TesB, Acyl-CoA thioesterase [Lipid metabolism].	6.5483e-122
CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit	gnl|CDD|178415	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain.	0
CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.1722e-168
CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase	gnl|CDD|99743	cd06450, DOPA_deC_like, DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and glutamate decarboxylase (GDC). DDC is active as a dimer and catalyzes the decarboxylation of tyrosine. GDC catalyzes the decarboxylation of glutamate and HDC catalyzes the decarboxylation of histidine.	5.02668e-121
CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit	gnl|CDD|223107	COG0028, IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism].	6.88462e-137
CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein	gnl|CDD|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	3.65701e-23
CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.62199e-13
CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG	gnl|CDD|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	9.59339e-157
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	gnl|CDD|374030	pfam15698, Phosphatase, Phosphatase. Members of this family have phosphatase activity.	1.42957e-133
CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB	gnl|CDD|99790	cd06193, siderophore_interacting, Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from transferrin and lactoferrin for bacterial uptake, contributing to pathogen virulence. Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport mechanism of photosystem I. FNR transfers electrons from reduced ferredoxin to FAD (forming FADH2 via a semiquinone intermediate) and then transfers a hydride ion to convert NADP+ to NADPH. FNR has since been shown to utilize a variety of electron acceptors and donors and has a variety of physiological functions including nitrogen assimilation, dinitrogen fixation, steroid hydroxylation, fatty acid metabolism, oxygenase activity, and methane assimilation in a variety of organisms. FNR has an NAD(P)-binding sub-domain of the alpha/beta class and a discrete (usually N-terminal) flavin sub-domain which vary in orientation with respect to the NAD(P) binding domain. The N-terminal moeity may contain a flavin prosthetic group (as in flavoenzymes) or use flavin as a substrate. Because flavins such as FAD can exist in oxidized, semiquinone (one-electron reduced), or fully reduced hydroquinone forms, FNR can interact with one and two electron carriers. FNR has a strong preference for NADP(H) vs NAD(H).	4.55184e-62
CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC	gnl|CDD|223687	COG0614, FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism].	9.11851e-20

Protein sequences

>CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein
MHQLSRTHAWAHAPDRRYLHVMTDRRAYPSDLSDARWELIEPVLSVWRYERHGRALGFGRPPEHDLREIMNAILYVDRTGVQWRYLPHDFPNWNTVYGYFAKWQSDGIFAQLNGLLRELVRQREGRNAEPSACVIDAQSVKTSTSVPATSQGTDNAKKIVGRKRSIVTDTIGLLIAVLVTAASVQDSVAGTQLLDQVSAEHSSIRKVWVDGGYRQHFVEHAATLGIDMEITARTPGTRGFTPIPKRWAVERTYGWLMLHRRLARDYETRTARSEAMIHLAMTDLMARRLTGESTISWRDPANDNQPPISG
>CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase
MGNMPIPSRAALVDHLVRTRIAGDVATPRDNNLSHYRRLANGDRHYWLGLELGDRWTDEQDVLAVMAERCGVVDDPGHRTGQDTIDPELTVDGLERMAARLRKAAAGRERVLFATGHPGALIDVHSRTAAALRSAGCDIVRIPGGLTADEGYVVQFADVAVFERGASLWHTHSPEPMRAILDALETPPDLVVADHGWAGCAGQRGVDAVGYADSNDPALFLAEAEGTLQVTVPLDDHVVDPRFYEPMTAYLLDAAGLS
>CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R
MSTRTDAPTRREQILREAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFAGKDAMLAELLVGISGRLYDGGRKRVAEAAGDPERLLGALIDGHIDFALDDRALITLHDRELDRLRDSDRKLVRQLQRQYVELWVGVVRELYPAVAEAEVRGAVHAVFGLLNSTPHLGSYGSGLPGRAATETLLRRLAHGAFASLAPLAGR
>CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit
MQQAPVLGSAADPASAAWRANEAAHRTLGEELRARLAAARLGGGERSRQRHVARGKLLPRDRVDTLLDPGSPFLELAPLAAEGMYGGQAPAAGVIAGIGRVSGRECVIVANDATVKGGTYYPMTVKKHLRAQEVALENRLPCLYLVDSGGAFLPMQDEVFPDRDHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLVKAATGEVVTAEELGGGEVHAKVSGVTDHLAEDDAHALRIVRNIVATLPERGPLPWSVEPAEEPKADPFGLYGAVPVDSRTPYDVREVIARVVDGSRFQEFKSEFGQTLVTGFARIHGHPVGIVANNGILFSESAQKGAHFIELCDQRGLPLVFLQNISGFMVGRDYEAGGIAKHGAKMVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMGGEQAASVLATVKRDQLGDDWSAEDEEAFKAPIREQYETQGNAYYATARLWDDGVIDPVDTRQVLGLALTACANAPLTDPAFGVFRM
>CP032698.1|AYG82728.1|5483039_5485028_-|Acetyl-/propionyl-coenzyme-A-carboxylase-alpha-chain
MFTTVLVANRGEIAVRVIRTLRQLGIRSVAVFSDADAEARHVREADTAVRIGPAAASESYLRPELLIEAARRTGAQAVHPGYGFLAENAGFAQACAEAGLVFIGPPAEAISLMGDKIRAKETVQKAGVPVVPGSSGSGLSDAQLADAAREIGMPVLLKPSAGGGGKGMRLVREEALLGDEIAAARREARASFGDDTLLVERWIDRPRHIEIQVLADNHGHVIHLGERECSLQRRHQKIIEEAPSVLLDEATRAAMGEAAVQAARSCGYSGAGTVEFIVPGSDPSSYYFMEMNTRLQVEHPVTELITGVDLVEWQLRVAAGEQLPYEQKDITLTGHAIEARLCAEDPSRGFLPSGGTVLALREPQGDGVRTDSGLSEGTEVGSLYDPMLSKVIAYGPDRATALRKLRAALADTVTLCVPTNAGFLRRLLAHPAVVAGELDTGLVEREADSLVPDGVPEEVYAAAAAVRLDALRPAPTDGWTDPFAVPSGWRMGGEPKALAFPLRVSGLEPVTHPAPTTARVTADRVTVELDGLTHTFHRAGAWLGRDGDSWHVTDHDAVEAALSGRTHGGADTLAAPMPGTVTVVKVAVGDQVDAGQSLLVVEAMKMEHVISAPHAGTVTELDVTPGSTVAMDQVLAVVTPAVQESPQDSSQDSSQKSLEESS
>CP032698.1|AYG82727.1|5482104_5483043_-|Hydroxymethylglutaryl-CoA-lyase-YngG
MTDLPMVVPAEGLPARVRIHEVGARDGLQNEKTVVPTEVKAEFVHRLAAAGLTTVEATSFVHPKWVPQLADAEALFPMLGDLDGVALPVLVPNERGLDRALALGATRIAVFASATESFAKANLNRTVDESLAMFEPVVARAKADGAHVRGYLSMCFGDPWEGAVPVAQVVRVAKALMELGCDELSLGDTIGVATPAHVGALLTGLNDRSIATDAIGVHFHDTYGQALANTFAALQHGVSTVDASAGGLGGCPYAKSATGNLATEDLVWMLQGLGVDTGVDLGQLTATSVWMAEQLGRPSPSRTVRALSHQES
>CP032698.1|AYG82726.1|5480941_5482102_-|Acyl-CoA-dehydrogenase
MPLDHRLTPEHEELRRTVEEFAHDVIAPKIGDFYERHEFPYEIVREMGRMGLFGLPFPEEYGGMGGDYLALGIALEELARVDSSVAITLEAGVSLGAMPIFRFGTEEQKRQWLPRLCSGEALGAFGLTEPDCGSDAGGTRTTAVRDGDEWVINGSKCFITNSGTDITGLVTVTAVTGRKDDGRPLISSIIVPSGTPGFTVAAPYSKVGWNASDTRELSFSDVRVPVANLLGEEGRGYAQFLRILDEGRIAISALATGLAQGCVDESVKYAKERHAFGRPIGDNQAIQFKIADMELRAHMARVGWRDAASRLVHGEPFKKEAALAKLYSSTVAVDNAREGTQIFGGYGFMNEYPVARMWRDSKILEIGEGTSEVQRMLIARELGLPA
>CP032698.1|AYG82725.1|5479480_5480515_-|Fe(3+)-citrate-binding-protein-YfmC
MPHARASLPTRRGLLAMGGAIGIGAALAACGGGDKKSGSADGATGAAKSGPWSFKDDRGQTAQTKAAPKNIVAFTGTAAALFDYGITVKGVFGPTKTKDGNADVQAGSLDISKVEVIGNTYGEFSVEKYAALQPDVLITDMWQKDVLWYVPDNSKDKILKLAPSVALWAADQSMPAALQRRADLAKSLGADLNAKNVTDAKAAFEKASARLRAAAKANPGIKVLLGSASPDLFYVSEAKRSCDTRYFQELGVRFVTPKVDSQGFFESLSWENVGKYPADLILMDNRTGTLQPADLGSKPTWAQLPAVKAHQVVPRLTEPIYSYARVAPIVDALAQAIENAKKVA
>CP032698.1|AYG82724.1|5478641_5479478_-|Vibriobactin-utilization-protein-ViuB
MPAPAETAIAPFRLFDLRVVRARRLGRSLMRVTFGGFGDEDLSSFAAGGRDQSLSLFLPHPGQEAPVLPPVDDADGWWAAYRALPDGIRAVMRSYTVRAQRRAPLGGPGEIDIDFALHGDGGPASRWARSVRAGGRVTVLGPAVADNTAVRFRPPAGTDSVVIWADETALPAAAGILEWLPSGLPAQVWITAPATPEALPRVTAADARVTWLPSVSPLDAIRSAPLPGASPYVWIAGEASHVRSLRRHFVGERGLERGRVTFVGYWRRGRTEDDLRAA
>CP032698.1|AYG82723.1|5476319_5477768_-|L-2,4-diaminobutyrate-decarboxylase
MRAHLLNDTTAEHYRRSVTEGVERVARKLATTRRPFSGVGVDDLAPVIDRIDLDAPLGDTSAVLDELEDVYLRDAVYFHHPRYLAHLNCPVVIPAVLGEAVLSAVNSSLDTWDQSAGGTLIERRLIDWTAGRIGLGPAADGVFTSGGTQSNLQSLLLAREEAKTTDLARLRVFASECSHFSVQKSAQLLGMGRDSVVSIPTDHDKRMQTLALARALERCVSEGNVPMAVVATAGTTDFGSIDPLPGIAELCAQYGAWMHVDAAYGCGLLASPTPARRALLDGIERADSVTVDYHKSFFQPVSSSAVLVRDASTLRHATYHADYLNPRRAAEERIPNQVDKSLQTTRRFDALKLWMTLRTMGADGLGSLFDEVCELAEQGWQLLAADPRYDVVVQPTLSTLVFRYIPATITSPAEIDRANLYARKALFASGEAVVAGTKSGGRQYLKFTLLNPETGVDDIAAVLDLIAGHAEQYLGENLVHAS
>CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2
MHQALESLLDLLDLERIEEDIFRGRSRSALIPRVFGGQVAAQALVAAGRTVPAERTAHSLHAYFLRAGDPGAPIVYTVDRIRDGASFTTRRVVAIQHGQPIFHLSASFQRYEEGMEHQAAMPPAPDPESLPTAAEMLPRYASAFRDEGVVDRLIEARAAVDLRYVDAPPWASVGTPREPRSQVWFRTNGKLADDPLLHVCLATYVSDMTLLDSVLLAHGRGGWAVGDVVGASLDHAMWFHRPFRADEWLLYDQESPSASGGRGLGQARIYTQDGRLAITVIQEGVVRVPRP
>CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)
MRRTVFNEDHEAFRETLRAFIEAEVVPAYDEWFAQGIVPREFYYKLAELGIFGIRVDEEFGGAGIDSYKFEAVMYEETARAGVQFGGSGVHVLLGLPYIKMLATDEQKKRFLPKFVSGEEMWALAMTEPGTGSDLAGMKTTAKLSEDGTHYVLNGAKTFITGGVHADRVIVCARTDAPSAEDRRHGISLFAVDTKSEGYSVGRKLDKLGLKTSDTAELAFVDVKVPVEDLLGEENKGFYYLGHNLASERWGIAFGAYAQAKAAVRFASEYVRDRTVFGKPVASFQNTKFELAACQAEVDAAEAVADRALEALDAGELTPAEAASAKLFCTEVAHRVIDRCLQLHGGYGFMNEYPIARLYADNRVNRIYGGTSEIMKSIIAKNMGL
>CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein
MPEPTAQPTQPTPPTPPIALAALLARADLGLRQIAGPPDATIRWVHTTEMADPYPYLLGGELLMTAGVQLGDPELYVSRVVAAGAAALGFGVAPVYDAVPPALVEACARHGLPLLEVPPQTTFSGVARAVWLLMARAREDELRRVSEAQRALAAAASRPDPVRGVLRVLAGRLGGWAALMTPEGVVLDAAGGAPSAVVGVGVEGLVRVVSPSADGEDRRPNSAPPAFEERGSGGRAPGAPTGPRPTNAPPEGLGRGRGGENPPKAPAHAHPLTATDTLGDTHLAAYALAETTGTALAIATPHRAPGDHTIAGVAAVLLALLTAGRPGADEAARSAALVRMVLGGAPGDLAALLGEGPWVVVHARGQGAPPDLGTPLVDAAGQTVRALAPADREVTTHPGWTLGVSAPAALDGLAVADLQAARALERAEATRTPLARHRAAGFGALLDPEEAAAYARELLAPLSGPLRATLRTWLSLHGSWDRSAVALGVHRNTVRQRIGRCAALLGTDLDDMDVRTELWLALRSAEAHSGQCR
>CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase
MSSNETPRGPIDSSRIPRYAGPATFARLPRLDEVGTADVAVVGVPFDSGVSYRPGARFGGNAIREASRLLRPYNPAQDASPFALAQVADAGDIAANPFNINEAVETIEAAADDLLGTGARMMTLGGDHTIALPLLRSVAKKHGPVALLHFDAHLDTWDTYFGAEYTHGTPFRRAVEEGILDTEALSHVGTRGPLYGKQDLTDDEKMGFGIVTSADVYRRGADEVADQLRQRIGDRPLYISIDIDCLDPAHAPGTGTPEAGGMTSRELLEILRGLASCNLVSADVVEVAPAYDHAEITSVAASHTAYELTTIMSRQIAASRA
>CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit
MTHDHDIVLRPTAAQTAAALNPPPGRIGGDLVVETLAGLGATTVFGLPGQHALGMFDALRRSDLTYVGLRVENNAGFAADAYGRITGEAAPLLLSTGPGALTSLAALQEAAAASSPVIALSSQVPTAGVGGGRHGYLHELRDQQASFRDVVKSVHVVRAPSQIPSAIAAAWESALTAPHGPVWVEIPEDVLLAETVLPVVTPMDAFPEEIVPRPELTAVAAELLATAERPAIIAGGGVVRSDASGKLRALAERLDAPVVTTFGGKGAFPWEHPLSLQSWLEDRHTTDFLEDADVLLVVGSGLGELSSNYHTFKPRGRIVQIEADLGKLESNHPALGIHADARTALQALLETVPERTDPTAAERVRTLLDKVRARLDAQDLGEERRILAAVREALPAGAPSFWDMTILTYWAWSAWPGAMHSAQGAGGLGYGFPAALGAAVADPSGPVLAVSGDGGAMYSIAELATAKQYGLPVTWLIVDDGGYGILRAYMTDAFGEATATATELARPDFVALAESFGVPAVRTTPDTLAADLAKALAEPGPSVVVLSAVLRMFEPTHR
>CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein
MTEGAQQGWARRLTGYAWRYRRNVALSLGSSLAGMAVMALVPLITKVVIDDVIGAHTRSLAVWTGLLIASAVVVYALTYIRRYYGGRLALDVQHDLRTEMYRTITRLDGRRQDELSTGQVVGRATSDLQLIQGLLFMLPMTIGNVLLFVISVVIMAWLSPLLTLVALAVAPALWFIAKRSRTRLFPATWYAQGQAAAVAGVVDGAVSGVRVVKGFGQEDQETGKLREVGRRLFAGRMRTIKLNSRYTPALQAVPALGQVAMLALGGWLATRGEITLGTFVAFSTYLAQLVGPVRMLAMVLTVGQQARAGVERVLELIDTEPSLQDGTKELSPSAPATVEFDDVSFGYDDERPVLDGFSLDIRPGETVAVVGASGSGKSTVSMLLPRFYDVSHGAVLVGGHDVRELTLSSLRAAIGLVPEDSFLFSDTVRANIAYGKPDATQDEIEKATRAAQAHGFISELPKGYDTTVGEHGLTLSGGQRQRIALARAILTDPRLLVLDDATSAVDARVEHEIHEALASVMAGRTTLLIAHRRSTLGLADRIAVLDAGRLAAIGTHEELQRDSALYRRLLTDPDELGAVSPGHTPTAPAVEEEDHSVRDELDAEFDAERGITPPLWVREEKPESAAPGGMPATPELLAQVEALPPATDTPDIDEARAVQPEDSYGLRRLLRGFGLPLLVSLLLVAIDAGMSLLLPVLIRHGIDQGVSKLALGAVWAAAGLALLTVVIQWLAQTGETRMTGRTGERVLYTLRLKIFAQLQRLGLDYYERELTGRIMTRMTTDVDALATFLQTGLVTAFVSVVTFFGIMVALLVIDLQLALVVFATLPLLVVGTYFFRKKSVQAYELARERVGVVNADLQESVSGLRIVQAFRREHDGARRFAERSDHYRQARVRGQWLISVYFPFVQLLSSVAAAAVLIVGAGRVDHGTLTAGALVAYLLYIDLFFAPVQQLSQVFDGYQQASVSLGRIQELLQEKTSTSEAAAPLDVLSLRGEIAFENVDFAYGSADGSGDEPEEALSGVDLRIPAGQTVAFVGETGAGKSTLVKLVARFYDPTGGRVTADGTDLRDLDITAYRHRLGVVPQEAYLFPGTVRDAIAYGRPGASDAEVEAAARAVGAHDMIATLDGGYLHEVAERGRNLSAGQRQLIALARAELVDPDVLLLDEATAALDLATEAQVNQATERLTGRRTTLVVAHRLTTAARADRVVVMDQGRVVEDGTHAELLALDGKYARLWHTFTSTPEPTPTPG
>CP032698.1|AYG82739.1|5501081_5501468_+|hypothetical-protein
MFGGMKRNPAPTLAVLAATGSLLMFGPPSGSADAAAACAGRPVKTVGFSTGELRLYKGNGYACAVTEAKSPGPRRQMSVTIQARGGAPAGDSGAYTQRAGPVTVHVGNRCVRATGSISGSSAETGWVC
>CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase
MRKALRWLLSLVVLTGTIAATGATAGAATAAEPDIKDRILAIPGVSLIAEKPYNGYRYFVLSFTQPVDHHNPYRRATFQQRITVLHKDTARPTVMYTSGYEVSTNPGRSEPTAIVDGNQVSVEYRFFPESRPTPTDWSKDDIWQAASDQHAIFQALKPVYSKNWLTTGGSKGGMTATYYKRFYPRDMDGVVAYVAPNDVVNNEDSAYDRFFRTVGTKECRDKLEGVQRQALVRRESLEKKYQEYAAANGYTFATVGTLDKAYEAVVLDYVWGFWQYHLLAECDTLPADPAHASDQAIWDSVDTISGFSFYTDQGLAPYTAYYYQAGTQLGSPTIKQPWLGNLSRYGYQPPRNFVPRDIPMRFQPWAMRDVDSWVKHHADHMLYVYGQNDPWGAERFSLGAGARDSYVYTVAGGNHGSKVAQLPADQKAAATASILRWAGVGAGAVRAPFDAKLDATPTTREPTLHP
>CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase
MQHRTSRRSLLTSTAATAVLAALGLPLPAHALDAPAAAGRDRGLRALIARMSVEEKIGQLFVMRVYGHSATAPDQADIDANLRELGVRDAAELIARYHVGGIIYFSWAHNTRDPHQIAELSNGIQAAGLAQRVPLPLLIATDQEHGAVCRVGKPVTLFPGAMAMGAGGSARDARTLGRISGAELAAIGIRQDYSPDADVNVNPANPVIGVRSFGADPAAVARMVAAEVRGYQESSVAATAKHFPGHGDTTVDSHTGIPVINHSRAEWERLDAPPFRAAIAAGIDAIMTAHIQFPALDPSNDPATLSRPILTGILREELGFDGVVITDSLGMQGVRDKYGDDRVPVLALKAGVDQLLDPPRLDVAFNGVRAAVASGELSEARLDASLLRILRLKERRGLFARPYVSVRGVGRTVGTRAHLRAADEIAERTTTLLANPRGLLPLSRRSHRRLLIVGADPASPSGTTGPPTSVLAAALAELGFQTTVLPTGTLPSAAQIEAAVAAAVGRDAVIVGTYNAGAGGAQSRLVAALGASGVPVVHLALRNPYDVAYLSGYGASLATYSWTDVELRAAVRVLTGRARPRGHLPVAVPRPDDPASPLYPVGYGLTY
>CP032698.1|AYG82742.1|5505563_5506232_-|hypothetical-protein
MKLTIFAASGGIGRLAVQQAVAAGHEVTAAVRDPAKVTWDEVRTVAVDLSRPDPDALSEALAGADAVLSGLGAATKADFGVAERGTRAICEAMRATGVRRIVVISAAPIGTVPSPGRPNPPRHDPGDAFMQRSVAYPIVKAILKKRYADLARMEDVLRASSLDWTALRPPRLNDKALTRRYRTEVGRNVRGGGIISRADVAHCMLEILDDPATFRQTVGLSD

Crispr_ID: CP032698_72

• CRISPR_ID: CP032698_72
• CRISPR_location: 5500896-5500978
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_72

Consensus_repeat	Method
TTAGGGGCGCGGGGAACTGCGCG	CRISPRCasFinder

spacers of CP032698_72

>72.1|5500919|37|CP032698|CRISPRCasFinder
CCCAGCCACCCACGGTCCGCAGCCGAAAACGGGGTTT

CRISPR arrays and Neighbor proteins around CP032698_72

CRISPR arrays

The CRISPR arrays of CP032698_72

>merge|CP032698|72|5500896-5500978|CRISPRCasFinder
TTAGGGGCGCGGGGAACTGCGCGCCCAGCCACCCACGGTCCGCAGCCGAAAACGGGGTTTTTAGGGGCGCGGGGAACTGCGCG

>CP032698|72|52|5500896-5500978|CRISPRCasFinder
TTAGGGGCGCGGGGAACTGCGCG	CCCAGCCACCCACGGTCCGCAGCCGAAAACGGGGTTT
TTAGGGGCGCGGGGAACTGCGCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82742.1|5505563_5506232_-|hypothetical-protein	unknown	unknown	gnl|CDD|187555
CP032698.1|AYG82739.1|5501081_5501468_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82747.1|5508333_5509239_-|HTH-type-transcriptional-regulator-GltC	unknown	unknown	gnl|CDD|176115
CP032698.1|AYG82745.1|5507245_5508070_+|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG82744.1|5506909_5507131_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein	unknown	unknown	gnl|CDD|224055
CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase	unknown	unknown	gnl|CDD|212538
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG82746.1|5508056_5508344_+|hypothetical-protein	unknown	unknown	gnl|CDD|377231
CP032698.1|AYG82743.1|5506265_5506721_-|hypothetical-protein	unknown	unknown	gnl|CDD|225039
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	unknown	unknown	gnl|CDD|224857
CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit	unknown	unknown	gnl|CDD|178415
CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase	unknown	unknown	gnl|CDD|366376
CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG82748.1|5509410_5510337_+|putative-amino-acid-metabolite-efflux-pump	unknown	unknown	gnl|CDD|183142
CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|223107
CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase	unknown	unknown	gnl|CDD|283275
CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein	unknown	unknown	gnl|CDD|377939
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	unknown	unknown	gnl|CDD|374030
CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)	unknown	unknown	gnl|CDD|173849

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82742.1|5505563_5506232_-|hypothetical-protein	gnl|CDD|187555	cd05244, BVR-B_like_SDR_a, biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs. Human BVR-B catalyzes pyridine nucleotide-dependent production of bilirubin-IX beta during fetal development; in the adult BVR-B has flavin and ferric reductase activities. Human BVR-B catalyzes the reduction of FMN, FAD, and riboflavin. Recognition of flavin occurs mostly by hydrophobic interactions, accounting for the broad substrate specificity. Atypical SDRs are distinct from classical SDRs. BVR-B does not share the key catalytic triad, or conserved tyrosine typical of SDRs. The glycine-rich NADP-binding motif of BVR-B is GXXGXXG, which is similar but not identical to the pattern seen in extended SDRs. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.85152e-51
CP032698.1|AYG82747.1|5508333_5509239_-|HTH-type-transcriptional-regulator-GltC	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.92373e-65
CP032698.1|AYG82745.1|5507245_5508070_+|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.86627e-11
CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.1722e-168
CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase	gnl|CDD|212538	cd11592, Agmatinase_PAH, Agmatinase-like family includes proclavaminic acid amidinohydrolase. This agmatinase subfamily contains bacterial and fungal/metazoan enzymes, including proclavaminic acid amidinohydrolase (PAH, EC 3.5.3.22) and Pseudomonas aeruginosa guanidinobutyrase (GbuA) and guanidinopropionase (GpuA). PAH hydrolyzes amidinoproclavaminate to yield proclavaminate and urea in clavulanic acid biosynthesis. Clavulanic acid is an effective inhibitor of beta-lactamases and is used in combination with amoxicillin to prevent the beta-lactam rings of the antibiotic from hydrolysis and, thus keeping the antibiotic biologically active. GbuA hydrolyzes 4-guanidinobutyrate (4-GB) into 4-aminobutyrate and urea while GpuA hydrolyzes 3-guanidinopropionate (3-GP) into beta-alanine and urea. Mutation studies show that significant variations in two active site loops in these two enzymes may be important for substrate specificity. This subfamily belongs to the ureohydrolase superfamily, which includes arginase, agmatinase, proclavaminate amidinohydrolase, and formiminoglutamase.	6.02255e-167
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	5.70484e-31
CP032698.1|AYG82746.1|5508056_5508344_+|hypothetical-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	4.84943e-21
CP032698.1|AYG82743.1|5506265_5506721_-|hypothetical-protein	gnl|CDD|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	1.03179e-21
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	gnl|CDD|224857	COG1946, TesB, Acyl-CoA thioesterase [Lipid metabolism].	6.5483e-122
CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit	gnl|CDD|178415	PLN02820, PLN02820, 3-methylcrotonyl-CoA carboxylase, beta chain.	0
CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase	gnl|CDD|366376	pfam00933, Glyco_hydro_3, Glycosyl hydrolase family 3 N terminal domain.	2.75366e-125
CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase	gnl|CDD|283275	pfam05576, Peptidase_S37, PS-10 peptidase S37. These serine proteases have been found in Streptomyces species.	0
CP032698.1|AYG82748.1|5509410_5510337_+|putative-amino-acid-metabolite-efflux-pump	gnl|CDD|183142	PRK11453, PRK11453, O-acetylserine/cysteine exporter.	9.24628e-67
CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit	gnl|CDD|223107	COG0028, IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism].	6.88462e-137
CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.62199e-13
CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein	gnl|CDD|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	3.65701e-23
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	gnl|CDD|374030	pfam15698, Phosphatase, Phosphatase. Members of this family have phosphatase activity.	1.42957e-133
CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)	gnl|CDD|173849	cd01160, LCAD, Long chain acyl-CoA dehydrogenase. LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer.	4.61967e-145

Protein sequences

>CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein
MTEGAQQGWARRLTGYAWRYRRNVALSLGSSLAGMAVMALVPLITKVVIDDVIGAHTRSLAVWTGLLIASAVVVYALTYIRRYYGGRLALDVQHDLRTEMYRTITRLDGRRQDELSTGQVVGRATSDLQLIQGLLFMLPMTIGNVLLFVISVVIMAWLSPLLTLVALAVAPALWFIAKRSRTRLFPATWYAQGQAAAVAGVVDGAVSGVRVVKGFGQEDQETGKLREVGRRLFAGRMRTIKLNSRYTPALQAVPALGQVAMLALGGWLATRGEITLGTFVAFSTYLAQLVGPVRMLAMVLTVGQQARAGVERVLELIDTEPSLQDGTKELSPSAPATVEFDDVSFGYDDERPVLDGFSLDIRPGETVAVVGASGSGKSTVSMLLPRFYDVSHGAVLVGGHDVRELTLSSLRAAIGLVPEDSFLFSDTVRANIAYGKPDATQDEIEKATRAAQAHGFISELPKGYDTTVGEHGLTLSGGQRQRIALARAILTDPRLLVLDDATSAVDARVEHEIHEALASVMAGRTTLLIAHRRSTLGLADRIAVLDAGRLAAIGTHEELQRDSALYRRLLTDPDELGAVSPGHTPTAPAVEEEDHSVRDELDAEFDAERGITPPLWVREEKPESAAPGGMPATPELLAQVEALPPATDTPDIDEARAVQPEDSYGLRRLLRGFGLPLLVSLLLVAIDAGMSLLLPVLIRHGIDQGVSKLALGAVWAAAGLALLTVVIQWLAQTGETRMTGRTGERVLYTLRLKIFAQLQRLGLDYYERELTGRIMTRMTTDVDALATFLQTGLVTAFVSVVTFFGIMVALLVIDLQLALVVFATLPLLVVGTYFFRKKSVQAYELARERVGVVNADLQESVSGLRIVQAFRREHDGARRFAERSDHYRQARVRGQWLISVYFPFVQLLSSVAAAAVLIVGAGRVDHGTLTAGALVAYLLYIDLFFAPVQQLSQVFDGYQQASVSLGRIQELLQEKTSTSEAAAPLDVLSLRGEIAFENVDFAYGSADGSGDEPEEALSGVDLRIPAGQTVAFVGETGAGKSTLVKLVARFYDPTGGRVTADGTDLRDLDITAYRHRLGVVPQEAYLFPGTVRDAIAYGRPGASDAEVEAAARAVGAHDMIATLDGGYLHEVAERGRNLSAGQRQLIALARAELVDPDVLLLDEATAALDLATEAQVNQATERLTGRRTTLVVAHRLTTAARADRVVVMDQGRVVEDGTHAELLALDGKYARLWHTFTSTPEPTPTPG
>CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit
MTHDHDIVLRPTAAQTAAALNPPPGRIGGDLVVETLAGLGATTVFGLPGQHALGMFDALRRSDLTYVGLRVENNAGFAADAYGRITGEAAPLLLSTGPGALTSLAALQEAAAASSPVIALSSQVPTAGVGGGRHGYLHELRDQQASFRDVVKSVHVVRAPSQIPSAIAAAWESALTAPHGPVWVEIPEDVLLAETVLPVVTPMDAFPEEIVPRPELTAVAAELLATAERPAIIAGGGVVRSDASGKLRALAERLDAPVVTTFGGKGAFPWEHPLSLQSWLEDRHTTDFLEDADVLLVVGSGLGELSSNYHTFKPRGRIVQIEADLGKLESNHPALGIHADARTALQALLETVPERTDPTAAERVRTLLDKVRARLDAQDLGEERRILAAVREALPAGAPSFWDMTILTYWAWSAWPGAMHSAQGAGGLGYGFPAALGAAVADPSGPVLAVSGDGGAMYSIAELATAKQYGLPVTWLIVDDGGYGILRAYMTDAFGEATATATELARPDFVALAESFGVPAVRTTPDTLAADLAKALAEPGPSVVVLSAVLRMFEPTHR
>CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase
MSSNETPRGPIDSSRIPRYAGPATFARLPRLDEVGTADVAVVGVPFDSGVSYRPGARFGGNAIREASRLLRPYNPAQDASPFALAQVADAGDIAANPFNINEAVETIEAAADDLLGTGARMMTLGGDHTIALPLLRSVAKKHGPVALLHFDAHLDTWDTYFGAEYTHGTPFRRAVEEGILDTEALSHVGTRGPLYGKQDLTDDEKMGFGIVTSADVYRRGADEVADQLRQRIGDRPLYISIDIDCLDPAHAPGTGTPEAGGMTSRELLEILRGLASCNLVSADVVEVAPAYDHAEITSVAASHTAYELTTIMSRQIAASRA
>CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein
MPEPTAQPTQPTPPTPPIALAALLARADLGLRQIAGPPDATIRWVHTTEMADPYPYLLGGELLMTAGVQLGDPELYVSRVVAAGAAALGFGVAPVYDAVPPALVEACARHGLPLLEVPPQTTFSGVARAVWLLMARAREDELRRVSEAQRALAAAASRPDPVRGVLRVLAGRLGGWAALMTPEGVVLDAAGGAPSAVVGVGVEGLVRVVSPSADGEDRRPNSAPPAFEERGSGGRAPGAPTGPRPTNAPPEGLGRGRGGENPPKAPAHAHPLTATDTLGDTHLAAYALAETTGTALAIATPHRAPGDHTIAGVAAVLLALLTAGRPGADEAARSAALVRMVLGGAPGDLAALLGEGPWVVVHARGQGAPPDLGTPLVDAAGQTVRALAPADREVTTHPGWTLGVSAPAALDGLAVADLQAARALERAEATRTPLARHRAAGFGALLDPEEAAAYARELLAPLSGPLRATLRTWLSLHGSWDRSAVALGVHRNTVRQRIGRCAALLGTDLDDMDVRTELWLALRSAEAHSGQCR
>CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)
MRRTVFNEDHEAFRETLRAFIEAEVVPAYDEWFAQGIVPREFYYKLAELGIFGIRVDEEFGGAGIDSYKFEAVMYEETARAGVQFGGSGVHVLLGLPYIKMLATDEQKKRFLPKFVSGEEMWALAMTEPGTGSDLAGMKTTAKLSEDGTHYVLNGAKTFITGGVHADRVIVCARTDAPSAEDRRHGISLFAVDTKSEGYSVGRKLDKLGLKTSDTAELAFVDVKVPVEDLLGEENKGFYYLGHNLASERWGIAFGAYAQAKAAVRFASEYVRDRTVFGKPVASFQNTKFELAACQAEVDAAEAVADRALEALDAGELTPAEAASAKLFCTEVAHRVIDRCLQLHGGYGFMNEYPIARLYADNRVNRIYGGTSEIMKSIIAKNMGL
>CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2
MHQALESLLDLLDLERIEEDIFRGRSRSALIPRVFGGQVAAQALVAAGRTVPAERTAHSLHAYFLRAGDPGAPIVYTVDRIRDGASFTTRRVVAIQHGQPIFHLSASFQRYEEGMEHQAAMPPAPDPESLPTAAEMLPRYASAFRDEGVVDRLIEARAAVDLRYVDAPPWASVGTPREPRSQVWFRTNGKLADDPLLHVCLATYVSDMTLLDSVLLAHGRGGWAVGDVVGASLDHAMWFHRPFRADEWLLYDQESPSASGGRGLGQARIYTQDGRLAITVIQEGVVRVPRP
>CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein
MHQLSRTHAWAHAPDRRYLHVMTDRRAYPSDLSDARWELIEPVLSVWRYERHGRALGFGRPPEHDLREIMNAILYVDRTGVQWRYLPHDFPNWNTVYGYFAKWQSDGIFAQLNGLLRELVRQREGRNAEPSACVIDAQSVKTSTSVPATSQGTDNAKKIVGRKRSIVTDTIGLLIAVLVTAASVQDSVAGTQLLDQVSAEHSSIRKVWVDGGYRQHFVEHAATLGIDMEITARTPGTRGFTPIPKRWAVERTYGWLMLHRRLARDYETRTARSEAMIHLAMTDLMARRLTGESTISWRDPANDNQPPISG
>CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase
MGNMPIPSRAALVDHLVRTRIAGDVATPRDNNLSHYRRLANGDRHYWLGLELGDRWTDEQDVLAVMAERCGVVDDPGHRTGQDTIDPELTVDGLERMAARLRKAAAGRERVLFATGHPGALIDVHSRTAAALRSAGCDIVRIPGGLTADEGYVVQFADVAVFERGASLWHTHSPEPMRAILDALETPPDLVVADHGWAGCAGQRGVDAVGYADSNDPALFLAEAEGTLQVTVPLDDHVVDPRFYEPMTAYLLDAAGLS
>CP032698.1|AYG82730.1|5486832_5487438_+|Transcriptional-repressor-Mce3R
MSTRTDAPTRREQILREAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFAGKDAMLAELLVGISGRLYDGGRKRVAEAAGDPERLLGALIDGHIDFALDDRALITLHDRELDRLRDSDRKLVRQLQRQYVELWVGVVRELYPAVAEAEVRGAVHAVFGLLNSTPHLGSYGSGLPGRAATETLLRRLAHGAFASLAPLAGR
>CP032698.1|AYG82729.1|5485114_5486722_-|Methylmalonyl-CoA-carboxyltransferase-12S-subunit
MQQAPVLGSAADPASAAWRANEAAHRTLGEELRARLAAARLGGGERSRQRHVARGKLLPRDRVDTLLDPGSPFLELAPLAAEGMYGGQAPAAGVIAGIGRVSGRECVIVANDATVKGGTYYPMTVKKHLRAQEVALENRLPCLYLVDSGGAFLPMQDEVFPDRDHFGRIFYNQARMSGAGIPQIAAVLGSCTAGGAYVPAMSDEAVIVRNQGTIFLGGPPLVKAATGEVVTAEELGGGEVHAKVSGVTDHLAEDDAHALRIVRNIVATLPERGPLPWSVEPAEEPKADPFGLYGAVPVDSRTPYDVREVIARVVDGSRFQEFKSEFGQTLVTGFARIHGHPVGIVANNGILFSESAQKGAHFIELCDQRGLPLVFLQNISGFMVGRDYEAGGIAKHGAKMVTAVACTRVPKLTVVVGGSYGAGNYSMCGRAYSPRFLWMWPNAKISVMGGEQAASVLATVKRDQLGDDWSAEDEEAFKAPIREQYETQGNAYYATARLWDDGVIDPVDTRQVLGLALTACANAPLTDPAFGVFRM
>CP032698.1|AYG82739.1|5501081_5501468_+|hypothetical-protein
MFGGMKRNPAPTLAVLAATGSLLMFGPPSGSADAAAACAGRPVKTVGFSTGELRLYKGNGYACAVTEAKSPGPRRQMSVTIQARGGAPAGDSGAYTQRAGPVTVHVGNRCVRATGSISGSSAETGWVC
>CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase
MRKALRWLLSLVVLTGTIAATGATAGAATAAEPDIKDRILAIPGVSLIAEKPYNGYRYFVLSFTQPVDHHNPYRRATFQQRITVLHKDTARPTVMYTSGYEVSTNPGRSEPTAIVDGNQVSVEYRFFPESRPTPTDWSKDDIWQAASDQHAIFQALKPVYSKNWLTTGGSKGGMTATYYKRFYPRDMDGVVAYVAPNDVVNNEDSAYDRFFRTVGTKECRDKLEGVQRQALVRRESLEKKYQEYAAANGYTFATVGTLDKAYEAVVLDYVWGFWQYHLLAECDTLPADPAHASDQAIWDSVDTISGFSFYTDQGLAPYTAYYYQAGTQLGSPTIKQPWLGNLSRYGYQPPRNFVPRDIPMRFQPWAMRDVDSWVKHHADHMLYVYGQNDPWGAERFSLGAGARDSYVYTVAGGNHGSKVAQLPADQKAAATASILRWAGVGAGAVRAPFDAKLDATPTTREPTLHP
>CP032698.1|AYG82741.1|5503446_5505270_-|Beta-hexosaminidase
MQHRTSRRSLLTSTAATAVLAALGLPLPAHALDAPAAAGRDRGLRALIARMSVEEKIGQLFVMRVYGHSATAPDQADIDANLRELGVRDAAELIARYHVGGIIYFSWAHNTRDPHQIAELSNGIQAAGLAQRVPLPLLIATDQEHGAVCRVGKPVTLFPGAMAMGAGGSARDARTLGRISGAELAAIGIRQDYSPDADVNVNPANPVIGVRSFGADPAAVARMVAAEVRGYQESSVAATAKHFPGHGDTTVDSHTGIPVINHSRAEWERLDAPPFRAAIAAGIDAIMTAHIQFPALDPSNDPATLSRPILTGILREELGFDGVVITDSLGMQGVRDKYGDDRVPVLALKAGVDQLLDPPRLDVAFNGVRAAVASGELSEARLDASLLRILRLKERRGLFARPYVSVRGVGRTVGTRAHLRAADEIAERTTTLLANPRGLLPLSRRSHRRLLIVGADPASPSGTTGPPTSVLAAALAELGFQTTVLPTGTLPSAAQIEAAVAAAVGRDAVIVGTYNAGAGGAQSRLVAALGASGVPVVHLALRNPYDVAYLSGYGASLATYSWTDVELRAAVRVLTGRARPRGHLPVAVPRPDDPASPLYPVGYGLTY
>CP032698.1|AYG82742.1|5505563_5506232_-|hypothetical-protein
MKLTIFAASGGIGRLAVQQAVAAGHEVTAAVRDPAKVTWDEVRTVAVDLSRPDPDALSEALAGADAVLSGLGAATKADFGVAERGTRAICEAMRATGVRRIVVISAAPIGTVPSPGRPNPPRHDPGDAFMQRSVAYPIVKAILKKRYADLARMEDVLRASSLDWTALRPPRLNDKALTRRYRTEVGRNVRGGGIISRADVAHCMLEILDDPATFRQTVGLSD
>CP032698.1|AYG82743.1|5506265_5506721_-|hypothetical-protein
MQARMKSPAHVIPSAMPAILDILEAAKQGGVAGSTLELVHLRASQINGCAPCVYGGITSARKNGVDEDKLATVATWRESPFFDDAERAALALAEASTRLADRPDAVSDEVWDAAASHYDEKGLASLVLMIGVTNLFNRLNATTRQIAGGTW
>CP032698.1|AYG82744.1|5506909_5507131_-|hypothetical-protein
MEAHDVGTYVVHTGTDVYGPGKVIGTDGDWRRVRFVYFVASVAVGDLRAASAREEEEVCAWLMEKAARHGGNW
>CP032698.1|AYG82745.1|5507245_5508070_+|hypothetical-protein
MAIEDNPVSRIKYGEELRARREAAGLTQEELSQRAVMSRTHIAHIEAGRRRPDIADARRLDIVLGTGGFFERFLPSLDGPKVAEHFAEALEFEQQAILIRQYAPKLVPGFLQTEAYAREVLSSGHPPKDDEERDRLLAARLARAQVLDDFDKPVVWTMLDEAVLRRRIGGPAVMCEQLRHLVVLGESRRIRLHVLPYDAGAHAVLEGHVSLLWFSDLPPIAYVEGLKSGRVWELPSVVRQCQEVYDHALGDALSHTRSLALMRSIAEDYAHEAQ
>CP032698.1|AYG82746.1|5508056_5508344_+|hypothetical-protein
MKRSEHMIPDASVLPAWRKSSYSGGDSGQCLEVSEVWRKSTYSGESGGDCLEFSDSCATCVPVRDSKNPTGPAVVFGPEAWGAFVGAVKGGALNR
>CP032698.1|AYG82747.1|5508333_5509239_-|HTH-type-transcriptional-regulator-GltC
MLDLARLRALHAVHVHGSVAAAAATLGYTPSAISQQISKLERETRTTLLERRGRGIALTEDALHLVSAAGELMAIVERAEITLEERRGLPTGDLTIGAFATAARGLLPTALAALAGQHPTLRTRLSEVDPHVSVDLVAKGVIDLAVAHDWDIAPLPAPEGVEHAHIGDDLCDVLVPANHPLATRPAIVRADLAHEPWICQPPGSVCHDWLVRTLRADGHEPELRHQAAEYHTQLALVRAGLGIALIPRLGRGPLPDGVVALRLDPVPTRHVYALWRTGAARRPAITATVHALRAAWDSLSG
>CP032698.1|AYG82748.1|5509410_5510337_+|putative-amino-acid-metabolite-efflux-pump
MLAVLVAAVWGVNFVVIDVGLGHFPPLLFSALRFLVAALPAVFFVGRPKVAWKWIVAVGLVLGVAKFGLLFIGMSQGMPAGLSSLVLQVQAVFTAVVAMAVLGERLGGVRLLGMAVALVGIVVAGVDEGSGGPLLGFCLTVGAAACWGVSNVLTRRAAPPDALNFMVWVSVVPVLPLLALSLLFEGPSRDAEALAGFDWGGAGALVYVAWISTVFGFGAWGMLLRRYPASSVAPFSLLVPVFGMSSAAVLLGESVTPLRWCAAALLVGGVALTSLSRPQRPGTEVPGAVVRGGSRVARTRRAGRTAEA

Crispr_ID: CP032698_73

• CRISPR_ID: CP032698_73
• CRISPR_location: 5503352-5503447
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of CP032698_73

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGG	CRISPRCasFinder

spacers of CP032698_73

>73.1|5503376|48|CP032698|CRISPRCasFinder
GGCCGGACCGTTCAACCCCCGTCACGGGCGGGTGGGTGGGCAGCCCCC

CRISPR arrays and Neighbor proteins around CP032698_73

CRISPR arrays

The CRISPR arrays of CP032698_73

>merge|CP032698|73|5503352-5503447|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGCCGGACCGTTCAACCCCCGTCACGGGCGGGTGGGTGGGCAGCCCCCCGGGGTCTGGGGCGGAGCCCCGGT

>CP032698|73|53|5503352-5503447|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGG	GGCCGGACCGTTCAACCCCCGTCACGGGCGGGTGGGTGGGCAGCCCCC
CGGGGTCTGGGGCGGAGCCCCGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82739.1|5501081_5501468_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82751.1|5512062_5513280_+|hypothetical-protein	unknown	unknown	gnl|CDD|223650
CP032698.1|AYG82747.1|5508333_5509239_-|HTH-type-transcriptional-regulator-GltC	unknown	unknown	gnl|CDD|176115
CP032698.1|AYG82745.1|5507245_5508070_+|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG82744.1|5506909_5507131_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein	unknown	unknown	gnl|CDD|224055
CP032698.1|AYG82748.1|5509410_5510337_+|putative-amino-acid-metabolite-efflux-pump	unknown	unknown	gnl|CDD|183142
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG82746.1|5508056_5508344_+|hypothetical-protein	unknown	unknown	gnl|CDD|377231
CP032698.1|AYG82743.1|5506265_5506721_-|hypothetical-protein	unknown	unknown	gnl|CDD|225039
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	unknown	unknown	gnl|CDD|224857
CP032698.1|AYG82749.1|5510367_5511330_+|Carboxylesterase-NlhH	unknown	unknown	gnl|CDD|369561
CP032698.1|AYG82742.1|5505563_5506232_-|hypothetical-protein	unknown	unknown	gnl|CDD|187555
CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit	unknown	unknown	gnl|CDD|223107
CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein	unknown	unknown	gnl|CDD|377939
CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase	unknown	unknown	gnl|CDD|283275
CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)	unknown	unknown	gnl|CDD|173849
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	unknown	unknown	gnl|CDD|374030
CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase	unknown	unknown	gnl|CDD|212538
CP032698.1|AYG82750.1|5511346_5512066_+|hypothetical-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP032698.1|AYG82750.1|5511346_5512066_+|hypothetical-protein	WYL	COG2378_WYL_CAS-I:CAS-III	2e-51	170.1	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82751.1|5512062_5513280_+|hypothetical-protein	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	2.48618e-17
CP032698.1|AYG82747.1|5508333_5509239_-|HTH-type-transcriptional-regulator-GltC	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.92373e-65
CP032698.1|AYG82745.1|5507245_5508070_+|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.86627e-11
CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.1722e-168
CP032698.1|AYG82748.1|5509410_5510337_+|putative-amino-acid-metabolite-efflux-pump	gnl|CDD|183142	PRK11453, PRK11453, O-acetylserine/cysteine exporter.	9.24628e-67
CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	5.70484e-31
CP032698.1|AYG82746.1|5508056_5508344_+|hypothetical-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	4.84943e-21
CP032698.1|AYG82743.1|5506265_5506721_-|hypothetical-protein	gnl|CDD|225039	COG2128, COG2128, Uncharacterized conserved protein [Function unknown].	1.03179e-21
CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2	gnl|CDD|224857	COG1946, TesB, Acyl-CoA thioesterase [Lipid metabolism].	6.5483e-122
CP032698.1|AYG82749.1|5510367_5511330_+|Carboxylesterase-NlhH	gnl|CDD|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	4.06976e-55
CP032698.1|AYG82742.1|5505563_5506232_-|hypothetical-protein	gnl|CDD|187555	cd05244, BVR-B_like_SDR_a, biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs. Human BVR-B catalyzes pyridine nucleotide-dependent production of bilirubin-IX beta during fetal development; in the adult BVR-B has flavin and ferric reductase activities. Human BVR-B catalyzes the reduction of FMN, FAD, and riboflavin. Recognition of flavin occurs mostly by hydrophobic interactions, accounting for the broad substrate specificity. Atypical SDRs are distinct from classical SDRs. BVR-B does not share the key catalytic triad, or conserved tyrosine typical of SDRs. The glycine-rich NADP-binding motif of BVR-B is GXXGXXG, which is similar but not identical to the pattern seen in extended SDRs. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.85152e-51
CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit	gnl|CDD|223107	COG0028, IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism].	6.88462e-137
CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein	gnl|CDD|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	3.65701e-23
CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase	gnl|CDD|283275	pfam05576, Peptidase_S37, PS-10 peptidase S37. These serine proteases have been found in Streptomyces species.	0
CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)	gnl|CDD|173849	cd01160, LCAD, Long chain acyl-CoA dehydrogenase. LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer.	4.61967e-145
CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase	gnl|CDD|374030	pfam15698, Phosphatase, Phosphatase. Members of this family have phosphatase activity.	1.42957e-133
CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase	gnl|CDD|212538	cd11592, Agmatinase_PAH, Agmatinase-like family includes proclavaminic acid amidinohydrolase. This agmatinase subfamily contains bacterial and fungal/metazoan enzymes, including proclavaminic acid amidinohydrolase (PAH, EC 3.5.3.22) and Pseudomonas aeruginosa guanidinobutyrase (GbuA) and guanidinopropionase (GpuA). PAH hydrolyzes amidinoproclavaminate to yield proclavaminate and urea in clavulanic acid biosynthesis. Clavulanic acid is an effective inhibitor of beta-lactamases and is used in combination with amoxicillin to prevent the beta-lactam rings of the antibiotic from hydrolysis and, thus keeping the antibiotic biologically active. GbuA hydrolyzes 4-guanidinobutyrate (4-GB) into 4-aminobutyrate and urea while GpuA hydrolyzes 3-guanidinopropionate (3-GP) into beta-alanine and urea. Mutation studies show that significant variations in two active site loops in these two enzymes may be important for substrate specificity. This subfamily belongs to the ureohydrolase superfamily, which includes arginase, agmatinase, proclavaminate amidinohydrolase, and formiminoglutamase.	6.02255e-167
CP032698.1|AYG82750.1|5511346_5512066_+|hypothetical-protein	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.35259e-43

Protein sequences

>CP032698.1|AYG82740.1|5501640_5503041_+|Prolyl-tri/tetrapeptidyl-aminopeptidase
MRKALRWLLSLVVLTGTIAATGATAGAATAAEPDIKDRILAIPGVSLIAEKPYNGYRYFVLSFTQPVDHHNPYRRATFQQRITVLHKDTARPTVMYTSGYEVSTNPGRSEPTAIVDGNQVSVEYRFFPESRPTPTDWSKDDIWQAASDQHAIFQALKPVYSKNWLTTGGSKGGMTATYYKRFYPRDMDGVVAYVAPNDVVNNEDSAYDRFFRTVGTKECRDKLEGVQRQALVRRESLEKKYQEYAAANGYTFATVGTLDKAYEAVVLDYVWGFWQYHLLAECDTLPADPAHASDQAIWDSVDTISGFSFYTDQGLAPYTAYYYQAGTQLGSPTIKQPWLGNLSRYGYQPPRNFVPRDIPMRFQPWAMRDVDSWVKHHADHMLYVYGQNDPWGAERFSLGAGARDSYVYTVAGGNHGSKVAQLPADQKAAATASILRWAGVGAGAVRAPFDAKLDATPTTREPTLHP
>CP032698.1|AYG82739.1|5501081_5501468_+|hypothetical-protein
MFGGMKRNPAPTLAVLAATGSLLMFGPPSGSADAAAACAGRPVKTVGFSTGELRLYKGNGYACAVTEAKSPGPRRQMSVTIQARGGAPAGDSGAYTQRAGPVTVHVGNRCVRATGSISGSSAETGWVC
>CP032698.1|AYG82738.1|5496998_5500742_+|Multidrug-efflux-ATP-binding/permease-protein
MTEGAQQGWARRLTGYAWRYRRNVALSLGSSLAGMAVMALVPLITKVVIDDVIGAHTRSLAVWTGLLIASAVVVYALTYIRRYYGGRLALDVQHDLRTEMYRTITRLDGRRQDELSTGQVVGRATSDLQLIQGLLFMLPMTIGNVLLFVISVVIMAWLSPLLTLVALAVAPALWFIAKRSRTRLFPATWYAQGQAAAVAGVVDGAVSGVRVVKGFGQEDQETGKLREVGRRLFAGRMRTIKLNSRYTPALQAVPALGQVAMLALGGWLATRGEITLGTFVAFSTYLAQLVGPVRMLAMVLTVGQQARAGVERVLELIDTEPSLQDGTKELSPSAPATVEFDDVSFGYDDERPVLDGFSLDIRPGETVAVVGASGSGKSTVSMLLPRFYDVSHGAVLVGGHDVRELTLSSLRAAIGLVPEDSFLFSDTVRANIAYGKPDATQDEIEKATRAAQAHGFISELPKGYDTTVGEHGLTLSGGQRQRIALARAILTDPRLLVLDDATSAVDARVEHEIHEALASVMAGRTTLLIAHRRSTLGLADRIAVLDAGRLAAIGTHEELQRDSALYRRLLTDPDELGAVSPGHTPTAPAVEEEDHSVRDELDAEFDAERGITPPLWVREEKPESAAPGGMPATPELLAQVEALPPATDTPDIDEARAVQPEDSYGLRRLLRGFGLPLLVSLLLVAIDAGMSLLLPVLIRHGIDQGVSKLALGAVWAAAGLALLTVVIQWLAQTGETRMTGRTGERVLYTLRLKIFAQLQRLGLDYYERELTGRIMTRMTTDVDALATFLQTGLVTAFVSVVTFFGIMVALLVIDLQLALVVFATLPLLVVGTYFFRKKSVQAYELARERVGVVNADLQESVSGLRIVQAFRREHDGARRFAERSDHYRQARVRGQWLISVYFPFVQLLSSVAAAAVLIVGAGRVDHGTLTAGALVAYLLYIDLFFAPVQQLSQVFDGYQQASVSLGRIQELLQEKTSTSEAAAPLDVLSLRGEIAFENVDFAYGSADGSGDEPEEALSGVDLRIPAGQTVAFVGETGAGKSTLVKLVARFYDPTGGRVTADGTDLRDLDITAYRHRLGVVPQEAYLFPGTVRDAIAYGRPGASDAEVEAAARAVGAHDMIATLDGGYLHEVAERGRNLSAGQRQLIALARAELVDPDVLLLDEATAALDLATEAQVNQATERLTGRRTTLVVAHRLTTAARADRVVVMDQGRVVEDGTHAELLALDGKYARLWHTFTSTPEPTPTPG
>CP032698.1|AYG82737.1|5495224_5496901_+|Acetolactate-synthase-large-subunit
MTHDHDIVLRPTAAQTAAALNPPPGRIGGDLVVETLAGLGATTVFGLPGQHALGMFDALRRSDLTYVGLRVENNAGFAADAYGRITGEAAPLLLSTGPGALTSLAALQEAAAASSPVIALSSQVPTAGVGGGRHGYLHELRDQQASFRDVVKSVHVVRAPSQIPSAIAAAWESALTAPHGPVWVEIPEDVLLAETVLPVVTPMDAFPEEIVPRPELTAVAAELLATAERPAIIAGGGVVRSDASGKLRALAERLDAPVVTTFGGKGAFPWEHPLSLQSWLEDRHTTDFLEDADVLLVVGSGLGELSSNYHTFKPRGRIVQIEADLGKLESNHPALGIHADARTALQALLETVPERTDPTAAERVRTLLDKVRARLDAQDLGEERRILAAVREALPAGAPSFWDMTILTYWAWSAWPGAMHSAQGAGGLGYGFPAALGAAVADPSGPVLAVSGDGGAMYSIAELATAKQYGLPVTWLIVDDGGYGILRAYMTDAFGEATATATELARPDFVALAESFGVPAVRTTPDTLAADLAKALAEPGPSVVVLSAVLRMFEPTHR
>CP032698.1|AYG82736.1|5494172_5495138_+|Guanidinobutyrase
MSSNETPRGPIDSSRIPRYAGPATFARLPRLDEVGTADVAVVGVPFDSGVSYRPGARFGGNAIREASRLLRPYNPAQDASPFALAQVADAGDIAANPFNINEAVETIEAAADDLLGTGARMMTLGGDHTIALPLLRSVAKKHGPVALLHFDAHLDTWDTYFGAEYTHGTPFRRAVEEGILDTEALSHVGTRGPLYGKQDLTDDEKMGFGIVTSADVYRRGADEVADQLRQRIGDRPLYISIDIDCLDPAHAPGTGTPEAGGMTSRELLEILRGLASCNLVSADVVEVAPAYDHAEITSVAASHTAYELTTIMSRQIAASRA
>CP032698.1|AYG82735.1|5492244_5493846_-|hypothetical-protein
MPEPTAQPTQPTPPTPPIALAALLARADLGLRQIAGPPDATIRWVHTTEMADPYPYLLGGELLMTAGVQLGDPELYVSRVVAAGAAALGFGVAPVYDAVPPALVEACARHGLPLLEVPPQTTFSGVARAVWLLMARAREDELRRVSEAQRALAAAASRPDPVRGVLRVLAGRLGGWAALMTPEGVVLDAAGGAPSAVVGVGVEGLVRVVSPSADGEDRRPNSAPPAFEERGSGGRAPGAPTGPRPTNAPPEGLGRGRGGENPPKAPAHAHPLTATDTLGDTHLAAYALAETTGTALAIATPHRAPGDHTIAGVAAVLLALLTAGRPGADEAARSAALVRMVLGGAPGDLAALLGEGPWVVVHARGQGAPPDLGTPLVDAAGQTVRALAPADREVTTHPGWTLGVSAPAALDGLAVADLQAARALERAEATRTPLARHRAAGFGALLDPEEAAAYARELLAPLSGPLRATLRTWLSLHGSWDRSAVALGVHRNTVRQRIGRCAALLGTDLDDMDVRTELWLALRSAEAHSGQCR
>CP032698.1|AYG82734.1|5491018_5492176_-|Acryloyl-CoA-reductase-(NADH)
MRRTVFNEDHEAFRETLRAFIEAEVVPAYDEWFAQGIVPREFYYKLAELGIFGIRVDEEFGGAGIDSYKFEAVMYEETARAGVQFGGSGVHVLLGLPYIKMLATDEQKKRFLPKFVSGEEMWALAMTEPGTGSDLAGMKTTAKLSEDGTHYVLNGAKTFITGGVHADRVIVCARTDAPSAEDRRHGISLFAVDTKSEGYSVGRKLDKLGLKTSDTAELAFVDVKVPVEDLLGEENKGFYYLGHNLASERWGIAFGAYAQAKAAVRFASEYVRDRTVFGKPVASFQNTKFELAACQAEVDAAEAVADRALEALDAGELTPAEAASAKLFCTEVAHRVIDRCLQLHGGYGFMNEYPIARLYADNRVNRIYGGTSEIMKSIIAKNMGL
>CP032698.1|AYG82733.1|5490105_5490981_-|Acyl-CoA-thioesterase-2
MHQALESLLDLLDLERIEEDIFRGRSRSALIPRVFGGQVAAQALVAAGRTVPAERTAHSLHAYFLRAGDPGAPIVYTVDRIRDGASFTTRRVVAIQHGQPIFHLSASFQRYEEGMEHQAAMPPAPDPESLPTAAEMLPRYASAFRDEGVVDRLIEARAAVDLRYVDAPPWASVGTPREPRSQVWFRTNGKLADDPLLHVCLATYVSDMTLLDSVLLAHGRGGWAVGDVVGASLDHAMWFHRPFRADEWLLYDQESPSASGGRGLGQARIYTQDGRLAITVIQEGVVRVPRP
>CP032698.1|AYG82732.1|5488870_5489803_+|hypothetical-protein
MHQLSRTHAWAHAPDRRYLHVMTDRRAYPSDLSDARWELIEPVLSVWRYERHGRALGFGRPPEHDLREIMNAILYVDRTGVQWRYLPHDFPNWNTVYGYFAKWQSDGIFAQLNGLLRELVRQREGRNAEPSACVIDAQSVKTSTSVPATSQGTDNAKKIVGRKRSIVTDTIGLLIAVLVTAASVQDSVAGTQLLDQVSAEHSSIRKVWVDGGYRQHFVEHAATLGIDMEITARTPGTRGFTPIPKRWAVERTYGWLMLHRRLARDYETRTARSEAMIHLAMTDLMARRLTGESTISWRDPANDNQPPISG
>CP032698.1|AYG82731.1|5487556_5488333_+|putative-phosphatase
MGNMPIPSRAALVDHLVRTRIAGDVATPRDNNLSHYRRLANGDRHYWLGLELGDRWTDEQDVLAVMAERCGVVDDPGHRTGQDTIDPELTVDGLERMAARLRKAAAGRERVLFATGHPGALIDVHSRTAAALRSAGCDIVRIPGGLTADEGYVVQFADVAVFERGASLWHTHSPEPMRAILDALETPPDLVVADHGWAGCAGQRGVDAVGYADSNDPALFLAEAEGTLQVTVPLDDHVVDPRFYEPMTAYLLDAAGLS
>CP032698.1|AYG82742.1|5505563_5506232_-|hypothetical-protein
MKLTIFAASGGIGRLAVQQAVAAGHEVTAAVRDPAKVTWDEVRTVAVDLSRPDPDALSEALAGADAVLSGLGAATKADFGVAERGTRAICEAMRATGVRRIVVISAAPIGTVPSPGRPNPPRHDPGDAFMQRSVAYPIVKAILKKRYADLARMEDVLRASSLDWTALRPPRLNDKALTRRYRTEVGRNVRGGGIISRADVAHCMLEILDDPATFRQTVGLSD
>CP032698.1|AYG82743.1|5506265_5506721_-|hypothetical-protein
MQARMKSPAHVIPSAMPAILDILEAAKQGGVAGSTLELVHLRASQINGCAPCVYGGITSARKNGVDEDKLATVATWRESPFFDDAERAALALAEASTRLADRPDAVSDEVWDAAASHYDEKGLASLVLMIGVTNLFNRLNATTRQIAGGTW
>CP032698.1|AYG82744.1|5506909_5507131_-|hypothetical-protein
MEAHDVGTYVVHTGTDVYGPGKVIGTDGDWRRVRFVYFVASVAVGDLRAASAREEEEVCAWLMEKAARHGGNW
>CP032698.1|AYG82745.1|5507245_5508070_+|hypothetical-protein
MAIEDNPVSRIKYGEELRARREAAGLTQEELSQRAVMSRTHIAHIEAGRRRPDIADARRLDIVLGTGGFFERFLPSLDGPKVAEHFAEALEFEQQAILIRQYAPKLVPGFLQTEAYAREVLSSGHPPKDDEERDRLLAARLARAQVLDDFDKPVVWTMLDEAVLRRRIGGPAVMCEQLRHLVVLGESRRIRLHVLPYDAGAHAVLEGHVSLLWFSDLPPIAYVEGLKSGRVWELPSVVRQCQEVYDHALGDALSHTRSLALMRSIAEDYAHEAQ
>CP032698.1|AYG82746.1|5508056_5508344_+|hypothetical-protein
MKRSEHMIPDASVLPAWRKSSYSGGDSGQCLEVSEVWRKSTYSGESGGDCLEFSDSCATCVPVRDSKNPTGPAVVFGPEAWGAFVGAVKGGALNR
>CP032698.1|AYG82747.1|5508333_5509239_-|HTH-type-transcriptional-regulator-GltC
MLDLARLRALHAVHVHGSVAAAAATLGYTPSAISQQISKLERETRTTLLERRGRGIALTEDALHLVSAAGELMAIVERAEITLEERRGLPTGDLTIGAFATAARGLLPTALAALAGQHPTLRTRLSEVDPHVSVDLVAKGVIDLAVAHDWDIAPLPAPEGVEHAHIGDDLCDVLVPANHPLATRPAIVRADLAHEPWICQPPGSVCHDWLVRTLRADGHEPELRHQAAEYHTQLALVRAGLGIALIPRLGRGPLPDGVVALRLDPVPTRHVYALWRTGAARRPAITATVHALRAAWDSLSG
>CP032698.1|AYG82748.1|5509410_5510337_+|putative-amino-acid-metabolite-efflux-pump
MLAVLVAAVWGVNFVVIDVGLGHFPPLLFSALRFLVAALPAVFFVGRPKVAWKWIVAVGLVLGVAKFGLLFIGMSQGMPAGLSSLVLQVQAVFTAVVAMAVLGERLGGVRLLGMAVALVGIVVAGVDEGSGGPLLGFCLTVGAAACWGVSNVLTRRAAPPDALNFMVWVSVVPVLPLLALSLLFEGPSRDAEALAGFDWGGAGALVYVAWISTVFGFGAWGMLLRRYPASSVAPFSLLVPVFGMSSAAVLLGESVTPLRWCAAALLVGGVALTSLSRPQRPGTEVPGAVVRGGSRVARTRRAGRTAEA
>CP032698.1|AYG82749.1|5510367_5511330_+|Carboxylesterase-NlhH
MSRAAATVDGMTITDEDCLPETLAFNEQFEAAAASRPARGRTPSAATLALLRRDRLGGDTPPVRLPHGQDRVVEGGVRVRVFVPGRVDGVYLHLHGGGWAFGSADGQDERLWHLAEQTRLAVVSVDYRLAPEHPFPAGPDDCEIAARWLVRHAAAEFGTERLLIGGESAGAHLSLLTLLRLRDRHGITGAFRAAHLLFGPYDLSMTPSQRSFGPRALLSNTDAVRGSYELFTPGMGQEQRRNPEISPLFADLAGLPPARIVVGTEDPLLDDSLFLAARWQAAGAAVELGVVAGAMHGFTLFPLTITERELRRERDFLASA
>CP032698.1|AYG82750.1|5511346_5512066_+|hypothetical-protein
MNRTARLYALVEELRAAAPRPLTVPALATRFEVSTRTVQRDLQILMRTGVPVRAIPGRGGGWSIDPEMTLPPIRLTADEASALTAALAAAGALTPYAGAARTAAQKIVAAMAGPASAAARQLAARIVTVPTQGDCAIRTAVEEALANDRALRLSYTDAAGHESERVVEPAGLLVVDGRWYLIAWCRTRRAGRGFRLDRIAAAAPTGEQAQPHNMTDLLFGSAAADAVPPSVLAPLTPPR
>CP032698.1|AYG82751.1|5512062_5513280_+|hypothetical-protein
MRRRRRQSDAAPAPKAATRRGRGLRIQRILGGTRLPRPVSLGLGQPFARPARTLLTLAAIVLGVTTVTLSTGLTSTLVAYGNVGREDGGARIHVTTAGTDGDRTRPRLSDPEIEERLRSLPDAEGVRARALAQASMTGQTLPVFADFYRGDNSLYDHTIVKGRAPAAAGEIVAGPAFLTQRGLKLGDRVTLELNGRKVTATVVGQVIEGNARAVEASWATYGELAPGVGATEYTVRLAPGADARAYAEKVAALDPALHASVLDQGNAGTATVIAFATVFTALLTTVAALGVFNTVLLHIRERRRDLGMLKSIGMTPRQVVLMTVTSVAGLGAVGGLLGIPLGIAAHRLVVDHVGVVAFPESMKDVWHAPQLAAMLLAGVLIAVLGALVPARSAARMTIASVLHTE

Crispr_ID: CP032698_74

• CRISPR_ID: CP032698_74
• CRISPR_location: 5520236-5520336
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of CP032698_74

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGGGG	CRISPRCasFinder

spacers of CP032698_74

>74.1|5520262|49|CP032698|CRISPRCasFinder
CCGGAACCAACCAACCCGCTGCACGGGCGGGTGGGTGGGCAAAGGGGCT

CRISPR arrays and Neighbor proteins around CP032698_74

CRISPR arrays

The CRISPR arrays of CP032698_74

>merge|CP032698|74|5520236-5520336|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGCCGGAACCAACCAACCCGCTGCACGGGCGGGTGGGTGGGCAAAGGGGCTCGGGGGCTGGGGCGGAGCCCCAGGGG

>CP032698|74|54|5520236-5520336|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGG	CCGGAACCAACCAACCCGCTGCACGGGCGGGTGGGTGGGCAAAGGGGCT
CGGGGGCTGGGGCGGAGCCCCAGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82763.1|5527370_5527682_-|Copper-chaperone-CopZ	unknown	unknown	gnl|CDD|225328
CP032698.1|AYG82764.1|5527893_5528094_-|hypothetical-protein	unknown	unknown	gnl|CDD|107201
CP032698.1|AYG82762.1|5525422_5526733_+|Citrate-synthase-1	unknown	unknown	gnl|CDD|180164
CP032698.1|AYG82755.1|5516436_5517591_-|hypothetical-protein	unknown	unknown	gnl|CDD|368783
CP032698.1|AYG82761.1|5523022_5525245_+|ATP-dependent-RecD-like-DNA-helicase	unknown	unknown	gnl|CDD|273632
CP032698.1|AYG82748.1|5509410_5510337_+|putative-amino-acid-metabolite-efflux-pump	unknown	unknown	gnl|CDD|183142
CP032698.1|AYG82754.1|5515594_5516440_-|D-tagatose-3-epimerase	unknown	unknown	gnl|CDD|224007
CP032698.1|AYG82756.1|5517587_5518742_-|D-xylose-dehydrogenase	unknown	unknown	gnl|CDD|223745
CP032698.1|AYG82752.1|5513293_5514073_-|hypothetical-protein	unknown	unknown	gnl|CDD|224007
CP032698.1|AYG82759.1|5521727_5521970_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82765.1|5528336_5529344_-|Inositol-2-dehydrogenase/D-chiro-inositol-3-dehydrogenase	unknown	unknown	gnl|CDD|223745
CP032698.1|AYG82767.1|5530397_5531582_+|5-dehydro-2-deoxygluconokinase	unknown	unknown	gnl|CDD|275175
CP032698.1|AYG82749.1|5510367_5511330_+|Carboxylesterase-NlhH	unknown	unknown	gnl|CDD|369561
CP032698.1|AYG82750.1|5511346_5512066_+|hypothetical-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl|CDD|225253
CP032698.1|AYG82766.1|5529345_5530248_-|Inosose-dehydratase	unknown	unknown	gnl|CDD|275172
CP032698.1|AYG82760.1|5522111_5522702_-|hypothetical-protein	unknown	unknown	gnl|CDD|227244
CP032698.1|AYG82758.1|5520378_5521533_-|Capsule-biosynthesis-protein-CapA	unknown	unknown	gnl|CDD|378215
CP032698.1|AYG82757.1|5518955_5519996_+|HTH-type-transcriptional-regulator-GalS	unknown	unknown	gnl|CDD|224525
CP032698.1|AYG82753.1|5514628_5515468_-|Putative-glyoxylase-CFP32	unknown	unknown	gnl|CDD|319911
CP032698.1|AYG82751.1|5512062_5513280_+|hypothetical-protein	unknown	unknown	gnl|CDD|223650

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
CP032698.1|AYG82750.1|5511346_5512066_+|hypothetical-protein	WYL	COG2378_WYL_CAS-I:CAS-III	2e-51	170.1	0.3

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82764.1|5527893_5528094_-|hypothetical-protein	gnl|CDD|107201	PHA02519, PHA02519, plasmid partition protein SopA; Reviewed.	0.00145977
CP032698.1|AYG82762.1|5525422_5526733_+|Citrate-synthase-1	gnl|CDD|180164	PRK05614, gltA, citrate synthase.	0
CP032698.1|AYG82755.1|5516436_5517591_-|hypothetical-protein	gnl|CDD|368783	pfam06187, DUF993, Protein of unknown function (DUF993). This family consists of several hypothetical bacterial proteins of unknown function.	0
CP032698.1|AYG82761.1|5523022_5525245_+|ATP-dependent-RecD-like-DNA-helicase	gnl|CDD|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	0
CP032698.1|AYG82748.1|5509410_5510337_+|putative-amino-acid-metabolite-efflux-pump	gnl|CDD|183142	PRK11453, PRK11453, O-acetylserine/cysteine exporter.	9.24628e-67
CP032698.1|AYG82754.1|5515594_5516440_-|D-tagatose-3-epimerase	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	7.72703e-38
CP032698.1|AYG82756.1|5517587_5518742_-|D-xylose-dehydrogenase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.52533e-49
CP032698.1|AYG82752.1|5513293_5514073_-|hypothetical-protein	gnl|CDD|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	3.73807e-22
CP032698.1|AYG82763.1|5527370_5527682_-|Copper-chaperone-CopZ	gnl|CDD|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	2.13549e-11
CP032698.1|AYG82765.1|5528336_5529344_-|Inositol-2-dehydrogenase/D-chiro-inositol-3-dehydrogenase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.91697e-47
CP032698.1|AYG82767.1|5530397_5531582_+|5-dehydro-2-deoxygluconokinase	gnl|CDD|275175	TIGR04382, myo-inositol_catabolism_protein, 5-dehydro-2-deoxygluconokinase. All members of the seed alignment for this model are translated from the iolC gene of known or putative inositol catabolism operons. Members with characterized function are 5-dehydro-2-deoxygluconokinase, the enzyme catalyzing the fifth step in degradation from myo-inositol or closely related compounds. Note that many members of this family are fusion proteins with an additional C-terminal domain, of unknown function, described by pfam09863. [Energy metabolism, Sugars].	1.79418e-141
CP032698.1|AYG82749.1|5510367_5511330_+|Carboxylesterase-NlhH	gnl|CDD|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	4.06976e-55
CP032698.1|AYG82750.1|5511346_5512066_+|hypothetical-protein	gnl|CDD|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.35259e-43
CP032698.1|AYG82766.1|5529345_5530248_-|Inosose-dehydratase	gnl|CDD|275172	TIGR04379, myo-inositol_catabolism_protein, myo-inosose-2 dehydratase. Members of this family include the enzyme myo-inosose-2 dehydratase, product of the gene iolE, as found in inositol utilization cassettes in many species. [Energy metabolism, Sugars].	5.11736e-39
CP032698.1|AYG82760.1|5522111_5522702_-|hypothetical-protein	gnl|CDD|227244	COG4907, COG4907, Predicted membrane protein [Function unknown].	0.000179148
CP032698.1|AYG82758.1|5520378_5521533_-|Capsule-biosynthesis-protein-CapA	gnl|CDD|378215	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap. This protein is a putative poly-gamma-glutamate capsule biosynthesis protein found in bacteria. Poly-gamma-glutamate is a natural polymer that may be involved in virulence and may help bacteria survive in high salt concentrations. It is a surface-associated protein.	6.67614e-78
CP032698.1|AYG82757.1|5518955_5519996_+|HTH-type-transcriptional-regulator-GalS	gnl|CDD|224525	COG1609, PurR, Transcriptional regulators [Transcription].	9.38477e-97
CP032698.1|AYG82753.1|5514628_5515468_-|Putative-glyoxylase-CFP32	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	3.61792e-28
CP032698.1|AYG82751.1|5512062_5513280_+|hypothetical-protein	gnl|CDD|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	2.48618e-17

Protein sequences

>CP032698.1|AYG82757.1|5518955_5519996_+|HTH-type-transcriptional-regulator-GalS
MTATLADVAARAQVSPATVSRVLNGNYPVAAATRERVLRAVDELDYVLNGPASSLAAATSDLIGILVNDIADPFFGIMAGAAQAAIGEERGAREKLSVICNTGGSPERELTYLTLLQRQRAAAVIVTGGALEDPEHQAAVSAKLARLADAGTRIVLCGRPPLPGDSVTATLAFDNRGGGRRVTEHLIGLGHRRIGYVGGPTERTTTRHRLEGHRAAWTVAGLTLDDLVVHGSYDRRSGYDGVLELLRREPKLTAVVAANDTVALGACAALRDRGLSVPEDVSVAGFVDLPFSADAVPALTTVRLPLYEVGVRAGRLALGVEVAPPGGIATVHGELMSRASTTPPRP
>CP032698.1|AYG82756.1|5517587_5518742_-|D-xylose-dehydrogenase
MTERRTVRIAMNGVTGRMGYRQHLVRSLLALREQGGLDLGDGTTLWPEPVLVGRRAHVLKAMADQHGLTEWSTDLDAVLADPGIDIYFDAQVTSAREEAIGKAITAGKHIYTEKPTATSLAGALGLARRAREAGVKHGVVQDKLFLPGLLKLKRLIDGGFFGRILSVRGEFGYWVFEGDWQPAQRPSWNYRREDGGGIVVDMFPHWEYVLHELFGRVTSVTAHTATHIPRRWDEHGEPYAATADDAAYGIFQLEGGAVAQINSSWAVRVNRDELVEFQVDGTEGSAVAGLRNCRVQHRSSTPKPVWNPDLPATVSFRAQWQEVPDNDVFDNGFKAQWELFLRHVVLDEPYRWDLLAGARGVQLAELGLRSCAEGRRLDVPEIAL
>CP032698.1|AYG82755.1|5516436_5517591_-|hypothetical-protein
MRPLLLPRPDGTTVRYEPRADPLSLAPGPAPLSRTVFSAAHVVADPYADVSPDSPAAVDWEATLAFRRHLWAHGLGVAEAMDTAQRGMGLDWPAAAELITRSAAEAKAVGGRIACGVGTDQLTSGDVAQVTAAYEEQLGLVEGAGAQPILMASRALAASARSPEEYVSVYTDLLRQASGPVILHWLGPMFDPALDGYWGSTDLDAATETFLEVIAAHPDKVDGIKVSLLDARREVELRRRLPDGVRCYTGDDFHYPELIAGDEQGFSHALLGIFDPLGPLAARAVRALDEGDTDAFRALLDPTVELSRHLFEAPTRFYKTGVVFLAWLAGHQSHFTMVGGLQSARSLPHLARAYELADGLGLFPDPARAAARMTSLLTVQGVPQ
>CP032698.1|AYG82754.1|5515594_5516440_-|D-tagatose-3-epimerase
MTAPPPAVSVRFSINQMTVKQLSLPGLVEACVRLGVRGVGLWREPVARYGLDATAKLVRDAGVEVTSLCRGGFLTAADAAGRAAAIADNRAAIDEAATLGTDTLVLVSGGLPPGSKDLAGARERIADALSSLAPYAASRGVRLAIEPLHPMFASDRCVVSTLDQALAIAERFPASQVGVVVDTYHVWWDDRAPAAVARAGAAGRIHAFQLADWVTPLPAGVLNGRGQLGDGSVDLARWRSLVDAAGYPGPIEVELFNDALWAGDGVALLEETVRRFGEVLA
>CP032698.1|AYG82753.1|5514628_5515468_-|Putative-glyoxylase-CFP32
MPEYPEGAPCWVDAMFTDLEAAKTFYAEVLGWTFGEAASEFGSYTQAYSDGKAVAAVVPPMPGADAPSQWCLYFASPDAAATGEKIKAAGGELLMEPMRVGTFGTMLIAKEPSGAVFGVWQPGDHRGFEKTGEPGAFAWAEVFTRDAAAVDGFLPRVFPFQVQTMDMSDAGEGEGPGGDGGAGMDYKVFALGAGEPALGRMVMGSEFPPEVPSYVQVYFGVPDCDEAVAAVRRLGGRVHFGPVDSPFGRMAAVADAQGAGFAVIDMAKRVGAAPKMTPA
>CP032698.1|AYG82752.1|5513293_5514073_-|hypothetical-protein
MKLALSTLGLPGIPLAQVARLAARAGFHGVELRVHPEAHVHPGLDAGRRKAIAATFEASGIEILALAGYARVADPDDDSDLHQLIGLTRDLGAAHLRVFPGGAGSRGDDDTAVRRLTDASHLARDSNIRILLETHDSHRTGEAVARVLDRVGADADGVGALWDVMHTWLGGESPGESYRHLAPHLGYTQVKDIASAEDTTPLPLGAGVLPLAECLALLPPDGWVCWEYEKRWYPEAAPLPGLLRAGRRYLTSITPGGEG
>CP032698.1|AYG82751.1|5512062_5513280_+|hypothetical-protein
MRRRRRQSDAAPAPKAATRRGRGLRIQRILGGTRLPRPVSLGLGQPFARPARTLLTLAAIVLGVTTVTLSTGLTSTLVAYGNVGREDGGARIHVTTAGTDGDRTRPRLSDPEIEERLRSLPDAEGVRARALAQASMTGQTLPVFADFYRGDNSLYDHTIVKGRAPAAAGEIVAGPAFLTQRGLKLGDRVTLELNGRKVTATVVGQVIEGNARAVEASWATYGELAPGVGATEYTVRLAPGADARAYAEKVAALDPALHASVLDQGNAGTATVIAFATVFTALLTTVAALGVFNTVLLHIRERRRDLGMLKSIGMTPRQVVLMTVTSVAGLGAVGGLLGIPLGIAAHRLVVDHVGVVAFPESMKDVWHAPQLAAMLLAGVLIAVLGALVPARSAARMTIASVLHTE
>CP032698.1|AYG82750.1|5511346_5512066_+|hypothetical-protein
MNRTARLYALVEELRAAAPRPLTVPALATRFEVSTRTVQRDLQILMRTGVPVRAIPGRGGGWSIDPEMTLPPIRLTADEASALTAALAAAGALTPYAGAARTAAQKIVAAMAGPASAAARQLAARIVTVPTQGDCAIRTAVEEALANDRALRLSYTDAAGHESERVVEPAGLLVVDGRWYLIAWCRTRRAGRGFRLDRIAAAAPTGEQAQPHNMTDLLFGSAAADAVPPSVLAPLTPPR
>CP032698.1|AYG82749.1|5510367_5511330_+|Carboxylesterase-NlhH
MSRAAATVDGMTITDEDCLPETLAFNEQFEAAAASRPARGRTPSAATLALLRRDRLGGDTPPVRLPHGQDRVVEGGVRVRVFVPGRVDGVYLHLHGGGWAFGSADGQDERLWHLAEQTRLAVVSVDYRLAPEHPFPAGPDDCEIAARWLVRHAAAEFGTERLLIGGESAGAHLSLLTLLRLRDRHGITGAFRAAHLLFGPYDLSMTPSQRSFGPRALLSNTDAVRGSYELFTPGMGQEQRRNPEISPLFADLAGLPPARIVVGTEDPLLDDSLFLAARWQAAGAAVELGVVAGAMHGFTLFPLTITERELRRERDFLASA
>CP032698.1|AYG82748.1|5509410_5510337_+|putative-amino-acid-metabolite-efflux-pump
MLAVLVAAVWGVNFVVIDVGLGHFPPLLFSALRFLVAALPAVFFVGRPKVAWKWIVAVGLVLGVAKFGLLFIGMSQGMPAGLSSLVLQVQAVFTAVVAMAVLGERLGGVRLLGMAVALVGIVVAGVDEGSGGPLLGFCLTVGAAACWGVSNVLTRRAAPPDALNFMVWVSVVPVLPLLALSLLFEGPSRDAEALAGFDWGGAGALVYVAWISTVFGFGAWGMLLRRYPASSVAPFSLLVPVFGMSSAAVLLGESVTPLRWCAAALLVGGVALTSLSRPQRPGTEVPGAVVRGGSRVARTRRAGRTAEA
>CP032698.1|AYG82758.1|5520378_5521533_-|Capsule-biosynthesis-protein-CapA
MPAPARPRALSRHTATARACALVLGVLSAATSVTACSGSSSPAPASAAERSAPVSPEAAPAVTAVPTPDLPAGTITLAFGGDVHFTERTASRLAATPADPALGPIARTVASADFAMVNLETAITTRGAAEPKLYHFRTPPSALTALRDSGVDAVSMANNHAVDYGPAGLADTLDAVHHAPIPVLGIGANEAEAYKPYVKEIRGVKLAVLAASQVMDLTNDKFRAGPKKPGIASALDAAKLVAAVKRAKARADVVVVYLHWGTEGQSCPGAEQKSIAAKLAAAGATVVVGTHAHVMLGSGMLGSSYVNYGLGNLLWYGTSPYPHSNDSGVATVTVSGGRVVGQGFVPAEVDGRGVPMPLQGVGAKAVLDRLAALRPCASLTPAPH
>CP032698.1|AYG82759.1|5521727_5521970_+|hypothetical-protein
MSGFLDRAKEQAQSALNQGKQKVDEVQQQRAGNDLLKRLGAAYYAERHGSGSPEATQQALTAVQAHITAHGDAFLRGSGT
>CP032698.1|AYG82760.1|5522111_5522702_-|hypothetical-protein
MPTERAERSVSGMSDNPSPAADRQPSDPSLHQDVLDELGDDGLQRVAGLLGTDAAGARDMVGTTMSTLSGGLPPEDHEEVSRAVSEAAAEAPPQEAPLQGVATLGGGLGGMLSGGLAAGVLAKVARPVANVVAKKTGLPPATVAKALEVVLPAALAVLTKRAASKSSGQGGAAGGGGGGGLGGLLSKIFGGGGGRK
>CP032698.1|AYG82761.1|5523022_5525245_+|ATP-dependent-RecD-like-DNA-helicase
MSSVTGMAVVEGVLERITYANEESGYTVARVDTGRGGNDLLTVVGSLLGAQPGESLRMEGRWGSHPQYGKQFTVENYTTVLPATIQGIRRYLGSGLIKGIGPVFADRITRHFGADTLDIIEQDPKRLIEVPGLGPKRTKKIAAAWEEQKAIKEVMVFLQGVGVSTSIAVRIYKKYEDASISVVKNQPYRLAADVWGIGFLTADRIAQAVGIPHDSPERVKAGLQYALSQSTDQGHCFLPEERLIADSVKLLQVDTGLVIECLAELIAEEGAVRERVPGPDGGEPVAAVYLVPFHRAELSLAAQIGRLLRTAEDRMPSFADVDWDRALRWLAGRTGAELAPEQQEAVKLALTSKVAVLTGGPGCGKSFTVRSVVELARAKNAKVVLAAPTGRAAKRLAELTGAEASTVHRLLELKPGGDAAYDKDRPLDADLVVVDEASMLDLLLANKLVKAVAPGAHLLMVGDVDQLPSVGAGEVLRDLLAEGGPVPRVRLTRIFRQAQESGVVTNAHRINSGSHPLTSGLDDFFLFVEEETEDAGRTTVDVAARRIPAKFGLDPRRDIQVLAPMHRGPAGAGHLNGLLQQAITPARPDLPEKRFGGRVFRVGDKVTQIRNNYEKGANGVFNGTVGVVTALDLDEQSLTVRTDEDEEVSYDFDELDELAHAYAVTIHRSQGSEYPAVVIPVTTGAWMMLQRNLLYTAVTRAKKLVVLVGSRKAIGQAVRTVSAGRRCTALAHRLAGGHLV
>CP032698.1|AYG82762.1|5525422_5526733_+|Citrate-synthase-1
MRDDVSENANNAVVLRFGDGEYTYPVIDSTVGDKGFDIGKLRTQTGLVTLDSGYGNTAAYKSAITYLDGEQGILRYRGYPIEQLAERSTFVEVAYLLINGELPTVDQLSSFKSEITGHTLLHEDVKRFFDGFPRDAHPMAMLSSVVSALSTFYQDSHNPFDEKQRHLSTIRLLAKLPTIAAYAYKKSIGHPFVYPRNDLGYVENFLRMTFSVPAQEYELDPVVVSALDKLLILHADHEQNCSTSTVRLVGSSQANMFASISAGISALWGPLHGGANQSVLEMLEGIQANGGDVDSFIRKVKNKEDGVRLMGFGHRVYKSFDPRAKIIKAAAHDVLSALGKSDELLDIALKLEEHALSDDYFVSRNLYPNVDFYTGLIYRAMGFPTEMFTVLFALGRLPGWIAQWHEMIKEPGSRIGRPRQIYTGEVLRDFVPVEGR
>CP032698.1|AYG82763.1|5527370_5527682_-|Copper-chaperone-CopZ
MTAETETPVAATGSCCSPAGACHGGEAADVQVGAVTTVYRVSGMSCGHCEGAVSGEISEIEGVASVKAVAATGEVTVVSAAPLDEEAVRAAVDEAGYELVGLA
>CP032698.1|AYG82764.1|5527893_5528094_-|hypothetical-protein
MTDRRLWSYKEIAAHIRVQPDTVRSYRKHGLLPAPDLVENGKPYWFADTIRTWVARRPGNRGRRAD
>CP032698.1|AYG82765.1|5528336_5529344_-|Inositol-2-dehydrogenase/D-chiro-inositol-3-dehydrogenase
MSLGIAVIGTGRMGADHVRRIDSVIGGARVAAVADLDADRAREAAAGIEGCSVHTDPAAAMDAPGVAAVLIASSGPAHEAALLEAFARGLPVLCEKPLTPDPAGTLRVMEAELRLGRRLVTVGFMRRYDSEYQELQRTLEQGELGRALMLHCRHRNAQSPPFFTTEMLIRDSVVHEADATRWLLGQEVTAVQVLRPRPSSGAPQGLGDPQLVLFETSGGVVVDVEIFVNCGFGYEVHCEAVCERGTASIGAGSGLVTRGAGRAARAIPEDFTVRFAEAYDREVRAWVDGIRRGRVEGASAWDGYAAALVCEAGVRAQECGERVGVELPERPALYA
>CP032698.1|AYG82766.1|5529345_5530248_-|Inosose-dehydratase
MTTAKTRIRIGSAPDSWGVWFPDDPRQVPWRRFLDEVAGAGYRWIELGPYGYLPTDPARLTEETAVRELRVSAGTVFTGLHHGPAVWEKTWAHVSDVAALAQAVGARHLVVIPSFWRDDKTGAILEDSTLTAAQWRDLARQTERLAREVRDHYGLRVVVHPHADTHIDSEENVARFLHATDSDLVSLCLDTGHYAYCGGDSVKLIETYGERIGYLHLKQVDPEVLAQVRSAGTPFGPAVAQGVMCEPPHGVPALEPVLAAAQSLDVELFAIVEQDMYPCDPDKPLPIAERTRAFLRSCGA
>CP032698.1|AYG82767.1|5530397_5531582_+|5-dehydro-2-deoxygluconokinase
MDEAPYGSERGSGGRGPEPEGAGPEPEGAGPEPEGAGPEPEGAGPEPEGAGPEPEGAGPEPEGAGPEGDRASGDAPYDLITMGRIGVDLYPLQTGVSLAKVSSFGKFLGGSPSNVAVAAARLGRRVAVITRTGRDPFGEYLRAELGELGVDARWVTPVDGLPTPITFCEVFPPDDFPLYFYRLPKAPDLELWERELDLGAIRAARIFWMTGTGLCAEPSRAATLAALRARGREPGGARRATVFDLDWRPMFWADPHDARLHYRAALAHATVAVGNVDECEVATGEREPRAAAEALLAAGVELAVVKQGPKGVLAVHRDGTAVEVAPVPVDVVNGLGAGDAFGGALCHGLLAGWEVERVMRYANAAGAIVASRLACSSAMPYPAEVERVLEGGRA

Crispr_ID: CP032698_75

• CRISPR_ID: CP032698_75
• CRISPR_location: 5633289-5633388
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_75

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGGGG	CRISPRCasFinder

spacers of CP032698_75

>75.1|5633315|48|CP032698|CRISPRCasFinder
CCGAACCCTTCAATGCCCGTCACGGGCGGGTGGGTGGGTCAATGTGCT

CRISPR arrays and Neighbor proteins around CP032698_75

CRISPR arrays

The CRISPR arrays of CP032698_75

>merge|CP032698|75|5633289-5633388|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGGCCGAACCCTTCAATGCCCGTCACGGGCGGGTGGGTGGGTCAATGTGCTCGGGGTCTGGGGCGGAGCCCCAGGGG

>CP032698|75|55|5633289-5633388|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGG	CCGAACCCTTCAATGCCCGTCACGGGCGGGTGGGTGGGTCAATGTGCT
CGGGGTCTGGGGCGGAGCCCCAGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82852.1|5628564_5629854_+|hypothetical-protein	unknown	unknown	gnl|CDD|340887
CP032698.1|AYG82862.1|5640508_5641525_-|Aspartate-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|237845
CP032698.1|AYG82851.1|5627895_5628435_-|HTH-type-transcriptional-regulator-MhqR	unknown	unknown	gnl|CDD|197670
CP032698.1|AYG82846.1|5622926_5624012_-|putative-MscS-family-protein-YkuT	unknown	unknown	gnl|CDD|366370
CP032698.1|AYG82856.1|5633394_5634312_-|L-glyceraldehyde-3-phosphate-reductase	unknown	unknown	gnl|CDD|236676
CP032698.1|AYG82850.1|5627237_5627477_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82849.1|5625158_5627159_+|4-alpha-glucanotransferase	unknown	unknown	gnl|CDD|376788
CP032698.1|AYG82864.1|5643316_5646640_-|Serine-protease-AprX	unknown	unknown	gnl|CDD|173796
CP032698.1|AYG82861.1|5639640_5640138_+|hypothetical-protein	unknown	unknown	gnl|CDD|377693
CP032698.1|AYG82847.1|5624263_5624800_+|hypothetical-protein	unknown	unknown	gnl|CDD|224321
CP032698.1|AYG82848.1|5625010_5625154_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82865.1|5646907_5647360_+|RNA-pyrophosphohydrolase	unknown	unknown	gnl|CDD|240040
CP032698.1|AYG82858.1|5635717_5635996_-|hypothetical-protein	unknown	unknown	gnl|CDD|377231
CP032698.1|AYG82860.1|5636932_5639509_-|Aminopeptidase-N	unknown	unknown	gnl|CDD|274121
CP032698.1|AYG82857.1|5634409_5635630_+|allantoicase	unknown	unknown	gnl|CDD|237319
CP032698.1|AYG82853.1|5629896_5630859_+|hypothetical-protein	unknown	unknown	gnl|CDD|273359
CP032698.1|AYG82859.1|5635985_5636786_-|hypothetical-protein	unknown	unknown	gnl|CDD|238045
CP032698.1|AYG82854.1|5630996_5631920_+|hypothetical-protein	unknown	unknown	gnl|CDD|273359
CP032698.1|AYG82863.1|5642029_5643250_+|putative-lipoprotein-aminopeptidase-LpqL	unknown	unknown	gnl|CDD|349873
CP032698.1|AYG82855.1|5631942_5632863_+|HTH-type-transcriptional-regulator-GltC	unknown	unknown	gnl|CDD|176115

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82852.1|5628564_5629854_+|hypothetical-protein	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.09932e-48
CP032698.1|AYG82862.1|5640508_5641525_-|Aspartate-semialdehyde-dehydrogenase	gnl|CDD|237845	PRK14874, PRK14874, aspartate-semialdehyde dehydrogenase; Provisional.	0
CP032698.1|AYG82851.1|5627895_5628435_-|HTH-type-transcriptional-regulator-MhqR	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.28477e-17
CP032698.1|AYG82846.1|5622926_5624012_-|putative-MscS-family-protein-YkuT	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	7.31916e-39
CP032698.1|AYG82856.1|5633394_5634312_-|L-glyceraldehyde-3-phosphate-reductase	gnl|CDD|236676	PRK10376, PRK10376, putative oxidoreductase; Provisional.	2.35366e-84
CP032698.1|AYG82858.1|5635717_5635996_-|hypothetical-protein	gnl|CDD|377231	pfam04149, DUF397, Domain of unknown function (DUF397). The function of this family is unknown.	2.92148e-23
CP032698.1|AYG82849.1|5625158_5627159_+|4-alpha-glucanotransferase	gnl|CDD|376788	pfam02446, Glyco_hydro_77, 4-alpha-glucanotransferase. These enzymes EC:2.4.1.25 transfer a segment of a (1,4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1,4)-alpha-D-glucan.	4.84752e-164
CP032698.1|AYG82864.1|5643316_5646640_-|Serine-protease-AprX	gnl|CDD|173796	cd04857, Peptidases_S8_Tripeptidyl_Aminopeptidase_II, Peptidase S8 family domain in Tripeptidyl aminopeptidases_II. Tripeptidyl aminopeptidases II are member of the peptidase S8 or Subtilase family. Subtilases, or subtilisin-like serine proteases, have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure (an example of convergent evolution). Tripeptidyl aminopeptidase II removes tripeptides from the free N terminus of oligopeptides as well as having endoproteolytic activity. Some tripeptidyl aminopeptidases have been shown to cleave tripeptides and small peptides, e.g. angiotensin II and glucagon, while others are believed to be involved in MHC I processing.	6.86485e-59
CP032698.1|AYG82861.1|5639640_5640138_+|hypothetical-protein	gnl|CDD|377693	pfam06718, DUF1203, Protein of unknown function (DUF1203). This family consists of several hypothetical bacterial proteins of around 155 residues in length. Family members are present in Rhizobium, Agrobacterium and Streptomyces species.	4.0975e-43
CP032698.1|AYG82847.1|5624263_5624800_+|hypothetical-protein	gnl|CDD|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	2.82048e-22
CP032698.1|AYG82865.1|5646907_5647360_+|RNA-pyrophosphohydrolase	gnl|CDD|240040	cd04684, Nudix_Hydrolase_25, Contains a crystal structure of the Nudix hydrolase from Enterococcus faecalis, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity. They also contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	1.68203e-31
CP032698.1|AYG82860.1|5636932_5639509_-|Aminopeptidase-N	gnl|CDD|274121	TIGR02412, Aminopeptidase_N, aminopeptidase N, Streptomyces lividans type. This family is a subset of the members of the zinc metallopeptidase family M1 (pfam01433), with a single member characterized in Streptomyces lividans 66 and designated aminopeptidase N. The spectrum of activity may differ somewhat from the aminopeptidase N clade of E. coli and most other Proteobacteria, well separated phylogenetically within the M1 family. The M1 family also includes leukotriene A-4 hydrolase/aminopeptidase (with a bifunctional active site).	0
CP032698.1|AYG82857.1|5634409_5635630_+|allantoicase	gnl|CDD|237319	PRK13257, PRK13257, allantoicase; Provisional.	9.72957e-168
CP032698.1|AYG82853.1|5629896_5630859_+|hypothetical-protein	gnl|CDD|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	3.81845e-46
CP032698.1|AYG82859.1|5635985_5636786_-|hypothetical-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.4915e-13
CP032698.1|AYG82854.1|5630996_5631920_+|hypothetical-protein	gnl|CDD|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.78717e-18
CP032698.1|AYG82863.1|5642029_5643250_+|putative-lipoprotein-aminopeptidase-LpqL	gnl|CDD|349873	cd03876, M28_SGAP_like, M28 Zn-peptidase Streptomyces griseus aminopeptidase and similar proteins. Peptidase family M28; Streptomyces griseus Aminopeptidase (SGAP, Leucine aminopeptidase (LAP), aminopeptidase S, Mername-AA022 peptidase) subfamily. SGAP is a di-zinc exopeptidase with high preference towards large hydrophobic amino-terminal residues, with Leu being the most efficiently cleaved. It can accommodate all except Pro and Glu residues in the P1' position. It is a monomeric (30 kDa), calcium-activated and calcium-stabilized enzyme; its activation by calcium correlates with substrate specificity and it has thermal stability only in the presence of calcium. Although SGAP contains a calcium binding site, it is not conserved in many members of this subfamily. SGAP is present in the extracellular fluid of S. griseus cultures.	1.91844e-118
CP032698.1|AYG82855.1|5631942_5632863_+|HTH-type-transcriptional-regulator-GltC	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	5.81411e-50

Protein sequences

>CP032698.1|AYG82855.1|5631942_5632863_+|HTH-type-transcriptional-regulator-GltC
MLRPMSEWDIKKLHILRTLREQGTVTATAEVLLMTPSAVSQQLSNLAKQLGVTLLEAHGRRVRLTDAAHLVLRHAEVVFAQLERADAELAGYLQGEAGEVRIGAFSTAVPALVVPAVRALRDSHPALQVRVREAEAAEAFELLSAGSVDLALSLAAHAPSARDPKFALLPLLADPLDVALPTGHPLAAEPGLRLADLAHEPWIFGGSGPWSEITTAACEAAGFVPEQAHSAAGWTAILSMVEAGMGVALVPRMAAADRRAGVTTRILSADQPRRHVVAAVRRGAEGGPAVGRVLGALREVAGGRPA
>CP032698.1|AYG82854.1|5630996_5631920_+|hypothetical-protein
MTVLDRVRSTPRAAAVEKVGGASGLGLVFAAVATVVWSGSFVASRALHDSVPPVQAAFWRWLIAIAAVAPFALREAWRQRALIRRHLGYLTLASLLGITVYNTLVNQAGTSTSAGNMGMIMAASPVLMAVHERLTGGRLGARRTVGLLVAVTGVLLLVSGGSLTLDLAAGDVWMVAAALSFASYSVLLRRRPAQLGPLAFLFATFVLGALMLAPAYGVSLATQGGFAATPATVGPLLYVGVLSSALAFFAWNKAISLIGAARAGVVYYLQPVCVALLSYPLLGETTGPAQLLCMALILGGVVLGSRR
>CP032698.1|AYG82853.1|5629896_5630859_+|hypothetical-protein
MNKNRLVTVTLTALAPMSWGSTYYVTTQFLPADRPLFTGMMRALPAGLALLALTRRLPRGEWWWKAVVLGALNIGAFFPLLFLSAYRLPGGMAAVIGSVGPLWVAGLAALFLGEKPTLRTLLTGIAAALGVSLVVLKAAGAFDTIGVVAALGSSASMSAGTVFTKRWGRPEGTGPLVMTGWQLTAGGLLIAPIAFFVEGAPPALDGRNIAGYVYLALVNTAVAYWLWFRGIGRMTATSVTFLGPLSPLTAAVIGWAALGQALAPVQLLGMAIAFGATLAGQAAPKPLRAATAPGTREPAAPEAPEIPAAPKKPSGLAKSL
>CP032698.1|AYG82852.1|5628564_5629854_+|hypothetical-protein
MRTFRSRTRTRTPRIPGERRMLVAMAVDATGSGMYVPFSLVFFHHVTGLSFATVGLVLTVVGLLGLGALPIAGAAVDRYGAQRVQLLLYGVRGTGFLLYPFAHSLPAFAVVALATAFGERAFPAVQQSLIGEVAQGADGDRLQASSRALRNGGLGAGSLLASLIVGFGGNAGFTAAAWLNAASFVLAALLMRGVKAERRAPVAAEVLPSAGYRQVFADRPFLGLTAANFLNSLGYAALSVLFPLYITTWLRGPQALTGIAFTLNTVMCAAGGVVVAARVRSRGARRTRSAALGSVLFAAAFAAQIVLGTFRPGSGLVLAGALLLIVALYTLGELVHSPSAGALSVAAAPEALRGRYLAAYQLSWSLSAALAPSLFTALMAVDGRLPWGVLVVTSLVAAAIVVRLERVLPGGAVRVIPAGRGVRVAVATG
>CP032698.1|AYG82851.1|5627895_5628435_-|HTH-type-transcriptional-regulator-MhqR
MNPPQSTPVPPTPPPAEVSSDAVDAITAQWAAVRPDLETLPMAVFGRIYRIARAMGDRMEKEYARFGIGRGEFDVIATLRRSGEPYTLSPRQLSATLMLTTGGMTGRLDKLERAGLLARSPDPTDRRGLRVTLTERGLRLVDESAAAGLAVQAEVLRAGLTEPESTQLSTLLRKLLAAL
>CP032698.1|AYG82850.1|5627237_5627477_+|hypothetical-protein
MDKKNALRAGAVAAGTTLMMLLMSSPALALTRDDGDDPGAGLSVIDTIGLFVVAPIALFAIIAGLVMVLDKSRKPAPKA
>CP032698.1|AYG82849.1|5625158_5627159_+|4-alpha-glucanotransferase
MTLARLAARHGVAMSYSPSPGLTVTVPEATVVAVLAALGVDASTPAAVHRALADAEAADLTRLLPPTLVRRGDGTVPGLGDELTVIGTPVAQLPLGVHQLDVRHRDGRTATATLIVAPPAVPGPPGRTHGFLVQLYSLLSTRSWGMGDLGDLAELAAWSGRTLGSGFVQVNPLHAAVPGAPTDPSPYRPSSRRFPDPVHLRVENIPEYAHVTERAALDELTERAAGLRQRVLSKGELIDRDAVWEVKREALELVHRVPLGPGRRAAYCDFLAEQGQALEDHATWCALVERYGPHWRRWPEGLRDPRSAATSRARRELIDRVTFHSWLAWLTDTQLAAAQRAAREAGMPVGVVHDLAVGVHPEGADAWAQQDAFAPGMSIGAPPDAFNAHGQDWGLPPWRPDVLAARGYAPYRDLLQGLLRHAGALRIDHVMGLFRLWWVPEGHPPTDGTYVHYDAEAMLAVLALEAHRAGAVVIGEDLGTVEPGVREALAAREVLGTSVLWFERDWAGDGRPLAPEAWRSGCLATATTHDLPSTAARLTGEHVQLRHRLGLLTGPLAQEQGAARAEVTEWLGHLERLGLLPDAPGDEEAEIRAVHRFLLRTPARMVGVWLPDAVGDRRPQNLPGTWDQYPNWRLPVAGPDAGPLTLEAIVASPRLHALMRVFAGEP
>CP032698.1|AYG82848.1|5625010_5625154_+|hypothetical-protein
MVATAPEQPLTSEPPMADAEPLISEPPMGETAPLTSEPTPVAAAAGF
>CP032698.1|AYG82847.1|5624263_5624800_+|hypothetical-protein
MPHVLVLNASYEPLGVVPLRRALVLVLENKAVSLEESGAFLHSATRAVAAPSVVRLKRFVRVPYRGPVPLTRRALFARDGGRCMYCGGVATSVDHVIPRSRGGQHAWENVVAACRRCNHVKADRHLMELGWRLRHQPAPPTGLAWRIIGTGHRDPRWLPYLQPFGADDALARIDGISA
>CP032698.1|AYG82846.1|5622926_5624012_-|putative-MscS-family-protein-YkuT
MNWSAVLADGSPPPTAPPTLQDAQKSATEAAGWVEQNWSTWLYVGFRILLIIVIASVLRVLVRRALTKLIDRMNRSAQAVEGTALGGLLVNAERRRQRSEAIGSVLRSVASFLIMGTAALMVLGVLNIDLAPLLASAGVAGVAIGFGARNLVTDFLSGVFMILEDQYGVGDSIDAGVASGEVIEVGLRVTKLRGADGEIWYVRNGEIKRIGNLSQGWATAGVDVRVRASEDLERLRTVINEATESLAKDEPWNERLWGPVEILGLDEVLLDSMVVRVSAKTMPGKALSVERELRWRIKIALDAAGIRIVGGLPLAEEPPVVDPSAAVAAPSALANPTSPQSLATTPIPNPAPNSASSNLSK
>CP032698.1|AYG82856.1|5633394_5634312_-|L-glyceraldehyde-3-phosphate-reductase
MTTTSETITAAAAGSWQLGDLTVNRIGFGTMRLPQRGPALRADAVPRDRATAIAVLRKAVELGVNHLDTAAFYFSPLRSANELINRALAPYADDLVITTKVGPCRLPSGEWGEHARTPGALRGQVEENLRQLGRDHLDVVNLRIVGGDSIAERFGALAELREAGLIRHLGLSNVRPAHLDEALAIAPVVCVQNPYGIGAPAEQEEMLRLCGERGVAFVPFYAIAGVGRERGAGAGGAGGEDEEVLAVARERGVSAAQVRLAWTLGRGAHVLAIPGTGDVDHLVDNVAAGALRLTPAELSRLTRTP
>CP032698.1|AYG82857.1|5634409_5635630_+|allantoicase
MDVSGGGGESQTMTPATENTETAQTAQTAETAETASTVDPHANDAAPYSGGDPYADYRAGDFAFTDLVDLADRRLGAGVIAANDEFFAERENLLVREPAVFDPEHFGHKGKIMDGWETRRRRGADADHVFPAPEDHDWALVRLGAPGVIKGIVVDTAHFRGNYPQRISVQATAVEGSPSPERLLADDVKWDEIIPPAPVRGHAENGFEITTGRRYTHIRLCQHPDGGVARLRVHGEVVPDPEWLDTLGTIDLVAVVNGGAYEDASDKFYSSPTQIILPGTSRKMDDGWENRRRRVRDTNDWVRFRLVAQGAIKAVEIDTAYLKGNSAGWIALSGRDGETGEWFEIIPRTRLQPDTLHRFRLPTQAVATHVRLDAFPDGGVARMRLHGALTDAGAAELRRRHAELTG
>CP032698.1|AYG82858.1|5635717_5635996_-|hypothetical-protein
MTTDRIIPRASALTGWRKSSYSGPDEGSCVEIADTDWRKSSYSGPDEGDCVEIADGHTTVPVRDSKNPDGPALLLGAESFTAFIDALKDSAL
>CP032698.1|AYG82859.1|5635985_5636786_-|hypothetical-protein
MTKAYGEWLREQRERAGLTQQQLAEMAIMSRTHIAHIEAGRRWPSEDDAKRLDRALNTGNVLVSFLPDKNARPVADHFEAAKQFEQQASMIREFALSCVPGILQTKAYARAVLSVRFPPLSAEERDQAVATRLKRSGILTDPVSPVVWALLDETVLHRPVGGPAVMAEQLVHLADLTDAGRIRVHVLPFGMGAHPLLLSMVTLMWFEDQPPIAYVEGLHTGTVHDSPALVERFQGTYDLALSDALPLKESLALLRATAKDYERDDN
>CP032698.1|AYG82860.1|5636932_5639509_-|Aminopeptidase-N
MPGTNLTREEAQRRAALLTVDSYEIELDLSGAQEGGTYRSATTVRFDSTEAGAETFIDLVAPTVHEVVLNGASLDPAAVFDDSRIALAGLEAGRNELRVVADCAYTNTGEGLHRFVDPVDQQAYLYTQFEVPDARRVFASFEQPDLKATFQFTVKAPSGWTVISNSPTPEPKDDVWVFEPTPRISSYITALIVGPYHSVHSSYEGPGGQSVPLGIYCRPSLAEFLDADEIFAVTRQGFDWFQEKFDCAYPFAKYDQLFVPEFNAGAMENAGAVTIRDQYVFRSKVTDAAYEVRAETILHELAHMWFGDLVTMEWWNDLWLNESFATYTSIACQAYAPGSKWPHAWTTFANSMKTWAYRQDQLPSTHPIMADIRDLDDVLVNFDGITYAKGASVLKQLVAYVGMDEFFQGVQAYFKAHAFGNTRLSDLLGALEETSGRDLKTWSKAWLETAGINVLRPEIAVDDSGVVTSFAVRQEAPALPAGAQGAPTLRPHRIAIGLYDLDEAGKLVRTDRIELDIDGELTAVDALVGKARPAVVLLNDDDLSYAKVRLDEESLRVVTEHLGDFTESLPRALCWASAWDMTRDGELATRDYLALVLSGITKESDIGVVQSLHRQVKLALDLYAAPEWRDAGLTQWTDATLAHLRTAEPGSDHQLAWARAFAATARTPQQLDLLQALLTGAEVIDGLAVDTELRWAFVGRLAATGVFDESEIAAELERDKTAAGERHAATARAARPTAEAKAEAWASVVESDSLPNAVQEAVIGGFVQTDQRELLAPYSEKFFAAVKGVWESRSHEIAQQIAVGLYPALLVSQETLDATDAWLSSAEPNAALRRLISESRAGVERALRARAADAAASA
>CP032698.1|AYG82861.1|5639640_5640138_+|hypothetical-protein
MTIYTARAIEPATLSELRALDDAGRPCVPFVDPEGGDPLRCCLRPVAPGERIALVSYAPLRRWAAGAGVSPGAYDEQGPVFIHADPCEGPSGEAGYPFARAGALRVLRRYDGRGRIAGGRLLEIPQAAESAFDAALDEAFSDPEVALVHVRAVEYGCFQFEVRRP
>CP032698.1|AYG82862.1|5640508_5641525_-|Aspartate-semialdehyde-dehydrogenase
MRVGIVGATGQVGAVMRKILVERAFPVEELRLFASARSAGTVLDGVTVEDASTADYTGLDIVLFSAGGATSRALAEKVASHGAVVIDNSSAWRGDPEVPLVVSEVNPHAIKDRPKGIIANPNCTTMAAMPVLRPLHDEAGLTALVATTYQAVSGSGLAGVAELHTQACKVAEAADQLTFDGDAVEFPEPGVYKRPIAFNVLPLAGNLVDDGSFETDEEQKLRNESRKILEIPELKVSGTCVRVPVFSGHSLQVNARFERPISVERAYELLGAAPGVELSEIPTPLQAAGKDASFVGRIRVDETVENGLALFLSNDNLRKGAALNAVQIAELVAAELKA
>CP032698.1|AYG82863.1|5642029_5643250_+|putative-lipoprotein-aminopeptidase-LpqL
MYGQLKRAGYDVAYQDFTFYESKTLRQKLTVQGRQLPVAAYGFSASTPAGGLTAELKAARVDDTPGCSLEDYASGGFAGKIALVKRGSCTFQEKEAVAAKAGAAGIVLYNHSGTEPVHGTVEAPANAHIPAAGITLADGEALAGQLAKGPVQVTLDVATEALAKKTRNVIAETRTGDPDQVVALGSHLDSVPAGPGINDNGSGSAGLLEVALKLADETKQTRKHPKQLPHKVRFAWWSGEELGLLGSEHYVKSLDESQKKQIKLYLNFDMIGSPNAAQLVYDGDDSDHKGAGPGPAGSAQIEGLINTYLDRRHVPHEGYDFDGRSDYGPFIAVGIPAGGTYTGAEEIKTPEQAKKWGGRAGEAFDPNYHAAGDTLDNIDARFFDLNIDVIAHAVGTYAYDLSSIQN
>CP032698.1|AYG82864.1|5643316_5646640_-|Serine-protease-AprX
MTTESPRPIPGARRTARIAAAAGLVAALVTAGAAPAFAATGGDDPTAPPVKTAPAKTAEDKLGKADEQRLAEAQAKGDKSVTVMVATAPGATSDVAEQLHAVAGATVGKQDDKLGYVRATLPTAKAEAALKAAAKLPSVHGIDLKQDIPLDDPTPSGDTTKSAKTLRTSGSYPAPDKNTPAKNPYNPSFETGAVDFVKQHPQADGRGVTIGILDSGVDLGHPALQKTTTGERKIVDWVTATDPVQDNDGTWLRANTAVAGPTFTAGGKTWKAPAGSYDFSTFAEKVTAGGDAKGDLNRDGDTSDSWGVLYDPVAGTVTVDLNNNNDFTDDAPMKPYKNGNQVGYFGTDNPATDVVERVPFTVEIRKNVVYDAAGHTSDYVNIGVIESEHGTHVAGITSANGLFGGAMSGAAPGAKLVSSRACNWDGGCTNIALTEGMIDLVTNRHVDIVNMSIGGLPALNDGNNARAELYKRLIDTYGVQLVISAGNDGPGVNTIGDPGLADHVISVGAAISKETWAANYGSGVSTAYQMMPFSSRGPREDGGFTPTLSAPGAAINSTQTWLPGSPVKESGYDLPAGYSMLQGTSMASPQAAGASALLISAAKQQGVDLPPADLRTALTSTAKHIKGVQAYSEGAGLINVVGAWDAIKQTAKKHAPAHEYTVTAPVSSALGFALKTPNVGTGIYDRESGLKAGQKKTYDVTVVRTTGPDKNVKHKLSLKNDDGTFKVLGDDEVNLPLGKPVTVKVQAQPKSGGVHSAILQVDDAKTVGVDQQIMATVIVATPIAGPGYTFSASSTVQRNSTTSYFVNVPAGAKNLEVRMGALRSGSQTRFISIHPYGVAVDPTGTPNCYPNYDNPANTCRPDLRSYANPQAGVWEIEVEARRTSPYLDNSYKLDVSVLGVTFDPATQTVPEAKTGTPAPVQWKVTNNFAALEGKLKGGSLGSAKVATPTIKTGETQTSTVTVGAGVEHLDVSIGGTSDKGADLDLYVLDQNGKTVAKSTTSSSDESVSVVKPAAGTYTIQVAGYAVPSGSTTYAYKDVYFAPSLGTLKVDESKTVKLASGTSAQVAADVVVAGAAPEGRQFFGTVQLVNERGTAAGTGSVIIGKVTQ
>CP032698.1|AYG82865.1|5646907_5647360_+|RNA-pyrophosphohydrolase
MAAYAVCVRETGGVQEILLARWVARDGTKRWTLPGGGMDHGEDPLETVVRELDEETGYVVEPVRLLGIDSINRRYPRKLGRFADFQGLRIVYEGRVTGGELRHETNGSTDLAAWHPLEGVADLDRVELVDVGVRLWRTRPPTGKAHPDVD

Crispr_ID: CP032698_76

• CRISPR_ID: CP032698_76
• CRISPR_location: 5755200-5755300
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_76

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGG	CRISPRCasFinder

spacers of CP032698_76

>76.1|5755224|53|CP032698|CRISPRCasFinder
GAGCCCGGAACCAACCAACCCGCTGCACGGGCGGGTGGGTGGGAAGACGCGCC

CRISPR arrays and Neighbor proteins around CP032698_76

CRISPR arrays

The CRISPR arrays of CP032698_76

>merge|CP032698|76|5755200-5755300|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGGAGCCCGGAACCAACCAACCCGCTGCACGGGCGGGTGGGTGGGAAGACGCGCCCGGGGTCTGGGGCGGAGCCCCGGC

>CP032698|76|56|5755200-5755300|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGG	GAGCCCGGAACCAACCAACCCGCTGCACGGGCGGGTGGGTGGGAAGACGCGCC
CGGGGTCTGGGGCGGAGCCCCGGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG82943.1|5746073_5747066_+|hypothetical-protein	unknown	unknown	gnl|CDD|236130
CP032698.1|AYG82946.1|5749249_5750242_-|Glucose--fructose-oxidoreductase	unknown	unknown	gnl|CDD|223745
CP032698.1|AYG82945.1|5747604_5749185_-|Propionyl-CoA-carboxylase-beta-chain	unknown	unknown	gnl|CDD|130187
CP032698.1|AYG82942.1|5745710_5745959_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82958.1|5763404_5763497_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG82941.1|5744757_5745645_+|Protein-YceI	unknown	unknown	gnl|CDD|377274
CP032698.1|AYG82951.1|5755364_5756969_-|Pentachlorophenol-4-monooxygenase	unknown	unknown	gnl|CDD|235728
CP032698.1|AYG82952.1|5756965_5758030_-|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl|CDD|187557
CP032698.1|AYG82953.1|5758026_5759094_-|Glucose-1-phosphate-thymidylyltransferase	unknown	unknown	gnl|CDD|273500
CP032698.1|AYG82959.1|5764217_5767118_-|Multidrug-resistance-protein-3	unknown	unknown	gnl|CDD|275309
CP032698.1|AYG82944.1|5747406_5747595_-|hypothetical-protein	unknown	unknown	gnl|CDD|379386
CP032698.1|AYG82950.1|5754184_5754853_+|dTDP-4-dehydrorhamnose-3,5-epimerase	unknown	unknown	gnl|CDD|380337
CP032698.1|AYG82948.1|5751743_5753045_-|GDP-4-keto-6-deoxy-D-mannose-3-dehydratase-/-pyridoxamine-phosphate-transaminase	unknown	unknown	gnl|CDD|237960
CP032698.1|AYG82956.1|5761523_5763044_+|Plipastatin-synthase-subunit-D	unknown	unknown	gnl|CDD|223395
CP032698.1|AYG82949.1|5753084_5754110_-|dTDP-6-deoxy-L-talose-4-dehydrogenase-(NAD(P)(+))	unknown	unknown	gnl|CDD|223528
CP032698.1|AYG82957.1|5763081_5763345_+|D-alanine--poly(phosphoribitol)-ligase-subunit-2	unknown	unknown	gnl|CDD|180828
CP032698.1|AYG82954.1|5759203_5759779_-|FMN-reductase-(NADPH)	unknown	unknown	gnl|CDD|274653
CP032698.1|AYG82947.1|5750234_5751692_-|hypothetical-protein	unknown	unknown	gnl|CDD|367562
CP032698.1|AYG82955.1|5759844_5760987_-|Alkanal-monooxygenase-alpha-chain	unknown	unknown	gnl|CDD|274922
CP032698.1|AYG82960.1|5767114_5768284_-|L-demethylnoviosyl-transferase	unknown	unknown	gnl|CDD|275309

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG82943.1|5746073_5747066_+|hypothetical-protein	gnl|CDD|236130	PRK07914, PRK07914, hypothetical protein; Reviewed.	2.23696e-88
CP032698.1|AYG82946.1|5749249_5750242_-|Glucose--fructose-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.38237e-54
CP032698.1|AYG82945.1|5747604_5749185_-|Propionyl-CoA-carboxylase-beta-chain	gnl|CDD|130187	TIGR01117, methylmalonyl-CoA_decarboxylase_alpha-subunit, methylmalonyl-CoA decarboxylase alpha subunit. This model describes methymalonyl-CoA decarboxylase aplha subunit in archaea and bacteria. Metylmalonyl-CoA decarboxylase Na+ pump is a representative of a class of Na+ transport decarboxylases that couples the energy derived by decarboxylation of carboxylic acid substrates to drive the extrusion of Na+ ion across the membrane. [Energy metabolism, ATP-proton motive force interconversion, Energy metabolism, Fermentation, Transport and binding proteins, Cations and iron carrying compounds].	0
CP032698.1|AYG82941.1|5744757_5745645_+|Protein-YceI	gnl|CDD|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	5.46057e-44
CP032698.1|AYG82951.1|5755364_5756969_-|Pentachlorophenol-4-monooxygenase	gnl|CDD|235728	PRK06184, PRK06184, hypothetical protein; Provisional.	7.17857e-103
CP032698.1|AYG82952.1|5756965_5758030_-|dTDP-glucose-4,6-dehydratase	gnl|CDD|187557	cd05246, dTDP_GD_SDR_e, dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs. This subgroup contains dTDP-D-glucose 4,6-dehydratase and related proteins, members of the extended-SDR family, with the characteristic Rossmann fold core region, active site tetrad and NAD(P)-binding motif. dTDP-D-glucose 4,6-dehydratase is closely related to other sugar epimerases of the SDR family. dTDP-D-dlucose 4,6,-dehydratase catalyzes the second of four steps in the dTDP-L-rhamnose pathway (the dehydration of dTDP-D-glucose to dTDP-4-keto-6-deoxy-D-glucose) in the synthesis of L-rhamnose, a cell wall component of some pathogenic bacteria. In many gram negative bacteria, L-rhamnose is an important constituent of lipopoylsaccharide O-antigen. The larger N-terminal portion of dTDP-D-Glucose 4,6-dehydratase forms a Rossmann fold NAD-binding domain, while the C-terminus binds the sugar substrate. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
CP032698.1|AYG82953.1|5758026_5759094_-|Glucose-1-phosphate-thymidylyltransferase	gnl|CDD|273500	TIGR01208, rmlA_long, glucose-1-phosphate thymidylylransferase, long form. The family of known and putative glucose-1-phosphate thymidyltransferase (also called dTDP-glucose synthase) shows a deep split into a short form (see TIGR01207) and a long form described by this model. The homotetrameric short form is found in numerous bacterial species that incorporate dTDP-L-rhamnose, which it helps synthesize, into the cell wall. It is subject to feedback inhibition. This form, in contrast, is found in many species for which it serves as a sugar-activating enzyme for antibiotic biosynthesis and or other, unknown pathways, and in which dTDP-L-rhamnose is not necessarily produced. Alternate name: dTDP-D-glucose synthase.	5.33902e-138
CP032698.1|AYG82959.1|5764217_5767118_-|Multidrug-resistance-protein-3	gnl|CDD|275309	TIGR04516, probable_glycosyltransferase, glycosyltransferase, activator-dependent family. Many biosynthesis clusters for secondary metabolites feature a glycosyltransferase gene next to a P450 homolog, often with the P450 lacking a critical heme-binding Cys. These P540-derived sequences seem to be allosteric activators of glycosyltransferases such as the member of this family. This model describes a set of related glycosyltransferases, many of which can be recognized as activator-dependent from genomic context.	1.5389e-73
CP032698.1|AYG82944.1|5747406_5747595_-|hypothetical-protein	gnl|CDD|379386	pfam13822, ACC_epsilon, Acyl-CoA carboxylase epsilon subunit. This family includes the epsilon subunits of propionyl-CoA carboxylase, EC:6.4.1.3, and acetyl-CoA carboxylase, EC:6.4.1.2. These enzymes are involved in the biosynthesis of long-chain fatty acids. The epsilon subunit is necessary for an efficient interaction between the alpha and beta subunits of these enzymes.	4.54689e-05
CP032698.1|AYG82950.1|5754184_5754853_+|dTDP-4-dehydrorhamnose-3,5-epimerase	gnl|CDD|380337	cd00438, cupin_RmlC, RmlC carbohydrate epimerase, involved in dTDP-L-rhamnose production. RmlC (deoxythymidine diphosphate (dTDP)-4-keto-6-deoxy-D-hexulose 3, 5-epimerase or dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; also known as RfbC) is a carbohydrate epimerase involved in the production of dTDP-L-rhamnose, a precursor of the bacterial cell wall constituent, L-rhamnose. L-Rhamnose (6-deoxy-l-mannose) plays an important role in the cell-wall structure of many bacterial species. It has been found to contribute to the virulence of several species, including the Gram-negative Salmonella enterica and Vibrio cholerae, where it is present as a part of the O-antigen, and is essential for the growth of Gram-positive bacteria such as Streptococcus pyogenes. RmlC converts dTDP-6-deoxy-D-xylo-4-hexulose to dTDP-6-deoxy-L-xylo-hexulose by catalyzing the epimerization of the 5-methyl and 3-hydroxyl groups of hexulose, the third of four steps in the dTDP-L-rhamnose biosynthetic pathway. RmlC belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	5.15795e-79
CP032698.1|AYG82948.1|5751743_5753045_-|GDP-4-keto-6-deoxy-D-mannose-3-dehydratase-/-pyridoxamine-phosphate-transaminase	gnl|CDD|237960	PRK15407, PRK15407, lipopolysaccharide biosynthesis protein RfbH; Provisional.	0
CP032698.1|AYG82956.1|5761523_5763044_+|Plipastatin-synthase-subunit-D	gnl|CDD|223395	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	3.56563e-104
CP032698.1|AYG82949.1|5753084_5754110_-|dTDP-6-deoxy-L-talose-4-dehydrogenase-(NAD(P)(+))	gnl|CDD|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	9.64434e-40
CP032698.1|AYG82957.1|5763081_5763345_+|D-alanine--poly(phosphoribitol)-ligase-subunit-2	gnl|CDD|180828	PRK07081, PRK07081, acyl carrier protein; Provisional.	2.66623e-08
CP032698.1|AYG82954.1|5759203_5759779_-|FMN-reductase-(NADPH)	gnl|CDD|274653	TIGR03567, FMN_reductase_NADPH, FMN reductase, SsuE family. Members of this protein family use NAD(P)H to reduce FMN and regenerate FMNH2. Members include the homodimeric, NAD(P)H-dependent enzyme SsuE from Escherichia coli, which serves as a partner to an FMNH2-dependent alkanesulfonate monooxygenase. It is induced by sulfate starvation. The NADH-dependent enzyme MsuE from Pseudomonas aeruginosa is outside the scope of this model (see model TIGR03566). [Central intermediary metabolism, Sulfur metabolism].	1.21939e-55
CP032698.1|AYG82947.1|5750234_5751692_-|hypothetical-protein	gnl|CDD|367562	pfam03559, Hexose_dehydrat, NDP-hexose 2,3-dehydratase. This family includes a range of proteins from antibiotic production pathways. The family includes gra-ORF27 product that probably functions at an early step, most likely as a dTDP-4-keto-6- deoxyglucose-2,3-dehydratase. Its homologs include dnmT from the daunorubicin biosynthetic gene cluster in S. peucetius, a similar gene from the daunomycin biosynthetic cluster in Streptomyces sp. strain C5, eryBVI from the erythromycin cluster in S. erythraea and snoH from the nogalamycin cluster in S. nogalater. The proteins in this family are composed of two copies of a 200 amino acid long unit that may be a structural domain.	2.26379e-120
CP032698.1|AYG82955.1|5759844_5760987_-|Alkanal-monooxygenase-alpha-chain	gnl|CDD|274922	TIGR04020, non-ribosomal_peptide_synthetase, natural product biosynthesis luciferase-like monooxygenase domain. This model describes a subfamily within the bacterial luciferase-like monooxygenase (LLM) family that regularly occurs within large non-ribosomal protein synthases/polyketide synthases, but also as small proteins. The LLM family includes members that bind either FMN or F420, and FMN is more likely in this case because many members are from species that lack F420 biosynthesis capability. An example member is the MupA protein of mupirocin biosynthesis in Pseudomonas fluorescens NCIMB 10586.	9.62971e-143
CP032698.1|AYG82960.1|5767114_5768284_-|L-demethylnoviosyl-transferase	gnl|CDD|275309	TIGR04516, probable_glycosyltransferase, glycosyltransferase, activator-dependent family. Many biosynthesis clusters for secondary metabolites feature a glycosyltransferase gene next to a P450 homolog, often with the P450 lacking a critical heme-binding Cys. These P540-derived sequences seem to be allosteric activators of glycosyltransferases such as the member of this family. This model describes a set of related glycosyltransferases, many of which can be recognized as activator-dependent from genomic context.	9.56727e-56

Protein sequences

>CP032698.1|AYG82950.1|5754184_5754853_+|dTDP-4-dehydrorhamnose-3,5-epimerase
MALPELESGRLPCGSMRIEETAVPDAYRIMPKLLTDPRGSFHESYRYDLLAAETGHAFVPRQVNYSASSRNTVRGLHGVTIPPGQAKLVSCVRGALLDVVVDVRVGSPTFGEHVTTILDAREGRAMFVAEGLAHGFVALTDDTCISYLCSTEYVPGTQLDLRALDPELGIAWARWLTGEPVLSEKDAGAPTVGEAAGLGLLPTYAQCVSLYGRGSEGSRRAA
>CP032698.1|AYG82949.1|5753084_5754110_-|dTDP-6-deoxy-L-talose-4-dehydrogenase-(NAD(P)(+))
MSVNDRRTGGREGGGAGSVVVLGATGFVGRHICEVFDAVGWTVTGVARSTREASTPYSVRALDVVSAEPEHIAALFGECGARVVVNAAGAVWQATEDDMTRANADLVERLVAATAPLDAPPRLIQLGSVHEYGPVPRTGITEDTPTAPVTPYGRSKLAGARALLDAAAAGRARGLVLRVSNVSGPGTHRASLLGMVAHHLVTSAPEPLRLAPLLAHRDFVDVRDVADAALAAAGSEASGQVLNIGGGQATSVRSLVARLTELAGATAEIVEAPSAGGRPPEAEWQRMDIGRAHRLLGWSPRRSLDDSLRDLLAHARLAAHREPLSSAFQVLPTTMAVSDHR
>CP032698.1|AYG82948.1|5751743_5753045_-|GDP-4-keto-6-deoxy-D-mannose-3-dehydratase-/-pyridoxamine-phosphate-transaminase
MSDTKARILEQVREYHLEKEPSREFVPGVSEIWPSGAVLEPADRVALVEAALDMRIAAGTSSRKFESRFARYMKRRKAHLVNSGSSANLLAMSALLSPHLEDRRLKPGDEVITVAAGFPTTVNPILQNGLVPVFVDVELRTYNTTAERIKAAVGPKTRAIMVAHALGNPFEVAEVAQIAEENDLFLIEDNCDAVGSLYNGQLTGTFGDLTTVSFYPAHHLTMGEGGCVLTSNLALARIVESLRDWGRDCWCEPGESDRCFKRFQYQLGTLPAGYDHKYIYSHIGYNLKATDLQAALGLTQLDKVDDFTAARRRNWQRLREGLEGVPHLILPEATLGSEPSWFGFVITVDPDAPFRRKELVNFLEERKIGTRNLFAGNLTRQPAYVDAPHRIVGDLTNSDIITEQTFWIGVYPGLTDEHTDFMTSSIRDFVAGW
>CP032698.1|AYG82947.1|5750234_5751692_-|hypothetical-protein
MSSTLAELTELLPVVQPREPVSVADRIAASAATTGGSLSTWDFHQWFAERRRTGGFRIERIPFSKLRGWSFEPGTGNLVHSSGRFFSVEGLHVTTDDGPHKEWFQPIIKQPEVGILGILVKEFDGVLHFLMQAKMEPGNRNLLQLSPTVQATRSNYTKVHQGTDVKYIEYFTGTGRGRILADVLQSEHGSWFYHKSNRNMIVEVDGDVPLDDDFCWLTLGQISELLHQDNLVNMDSRTVLACLPAYGAGAVRGDDFSQSLARSRDPEAGALLTDVDLLSWFTSERSRYDVRAERIPLDQVPGWTRDEARIGKDDGRWFNVVAVEVQAGNREVTSWTQPLIEPCSRGIAAFLTRSFDGVLHVLANAKVEGGFLDTVELAPTVQCSPDNFEGLQVRPPFLDLVLEAAPERVRYDAIHSEEGGRFLYAENRYLVIEADEQDAPIEPPTGYQWVTVSQLTALIKHGHYVNVQARTLLACLNAMGHLTDD
>CP032698.1|AYG82946.1|5749249_5750242_-|Glucose--fructose-oxidoreductase
MTERPLRIAVLGTADIARRRVLPAMAADPDIELTAVASRDGGRAREVADQFGCAAVESYDAVLTRDDVDAVYVPLPISLHAEWAGRALRAGKHVLAEKPLTADRPTTEALLDLARASGLVLMENVMFVHHPQHSVVRELVTSGAIGQLRAFSAAFAIPALPAGNIRHRPELGGGALLDVGYYPVRAALYFLGAGLEIVGAALENTGGSMVETSGAVLVRSPAGVLGQLAFGMEHAYRSAYELWGSEGRIRVEPAFTPSADHKPMVWITDAHGPRELTLAPHDQVAATVRAFVRAVRSGALQSPDAGECLEQASLLDAVRARATRTGAPRP
>CP032698.1|AYG82945.1|5747604_5749185_-|Propionyl-CoA-carboxylase-beta-chain
MTVTEQPSPGTAAVRVAELHLLREQARLGPSEKATEAQRAKGKLTARERIDLLLDPDSFQEVEQLRRHRAVGFGLEAKRPYTDGVVTGWGTVEGRTVFVYAHDFRIFGGALGEAHATKIHKIMDMAIAAGAPLVSLNDGAGARIQEGVSALAGYGGIFQRNTRASGVIPQISVMLGPCAGGAAYSPALTDFVFMVRETSQMFITGPDVVQAVTGEQITQNGLGGADVHAGVSGVAHFVHDDEETCLAEVRYLISMLPSNNREMPPALPPGNDPADRRNDVLLDLVPADGNRPYDMRKVLEEIVDHGDLLEVHEQWARNIICALARIDGQVVGILANQPQFLAGVLDIEASEKAARFVQLCDAFNIPLLTMVDVPGFLPGVSQEHGGIIRHGAKLLYAYCNATVPRISLILRKAYGGAYIVMDSQSIGADLTYAWPTNEIAVMGAEGAANVIFRREIAGSADPEAVRAEKIAAYKSELMHPYYAAERGLVDDVIDPAETRKVLAAALSMLRTKHADLPSRKHGNPPQ
>CP032698.1|AYG82944.1|5747406_5747595_-|hypothetical-protein
MSSEPLFRVLKGTPTEAELAALAVVLLSLTGESPAPALAPVIPLAAWRRHPYHPPVSWRRAA
>CP032698.1|AYG82943.1|5746073_5747066_+|hypothetical-protein
MATRKNSTDDPLAPVTLAVGQEDLLLDRAVQEVVAAARAADSDTDVRDLSSEQVQPGTLAELTSPSLFAERKVVVVRNAHDLSADTVKDVKAYLDAPAEEITLVLLHAGGVKGKGLLDAARKAGAREVACPKTTKPAERLTFVRQEFRALGRSATPEACQALVDSIGSDLRELASAASQLCADVEGTIDEEIVGRYYTGRAEASSFTVADRAVEGRAAEALEALRWSLSTGVAPVMITSALAQGVRAIGKLSSARGGRPADLARELGMPPWKIDRVRQQMRGWTPDGVSLALRAVAEADAGVKGGGDDPEYALEKAVVAIARAARAGRAG
>CP032698.1|AYG82942.1|5745710_5745959_-|hypothetical-protein
MNDVTRHVLVLPDRDAAEEVSTELTDLFGLAEEPQLVRDALAGEDDAEDAQWLVVVEDPSARFDPKALDALAAEHDGWLEAP
>CP032698.1|AYG82941.1|5744757_5745645_+|Protein-YceI
MFSRWFGKSSTSSPLRSGPLAGLSVPPTAGVLSCRVLDPVSEPVQRAEFTVSDASGRKVVAGETDPFGTVVTTVPAGEYRLAVTAEGYTPFHGNASVTASGLASLGDITLQVATPPTLPDPGEWELDPTHSQIGFTASHIGLARIHGRFNTFAGAIRIGERMEGSAMHVIIDTASIDTGVTMRDDHLRSGDFLDVGSYPTMEFYSDRFVHRGGGRWAIIGGLTLHGVSRTVTLDTQYLGLGTGLGGETRGACRASTELHREDFTLTWQTMLARGIAAIGSSISIDLDIQVVPKAG
>CP032698.1|AYG82951.1|5755364_5756969_-|Pentachlorophenol-4-monooxygenase
MTQLDATAPAPQVLVVGAGPVGLSAAHELARHGVRVRLVDAAAGPATTSRALATHARTLETYDQMGILDELLPRGQRVEHFTLHQNGRRLIRFDTDYSRLPTRFPFTLMVDQVITEEVLRTATARRGVEIEWGVRLTEFEDLGSDGVRAHLVHADGFAETMTVDWLVGTDGGHSTIRKQLGLKLEGESSETWLIADATVHCDLPKDSIHWMRTPTGTVMMVPFPEPGKWRLLDTAETSYGGDDAMVARRFSAKISTGTGRPAVVESPSWVSVFTIQQRMIGQMRNGRVLLAGDAAHVHSPASGQGMNTGVQDAVNLSWKLATVLRGEAPEALLDSYSDERVPVGAELLRTTKMATMLVQLRSRRAAAALRAAFTVLRSLPPVKGRIQRKIMGGMSALGLGYAAGPLAHASTPSAGVRPGERVARVTAPDLAASPGWQELVSELQRPQWLLLTFGPAPEDHFGPSVRVRTVNAPGPDALSDPAGHLSTALGAPSGTWLLIRPDGYLAARGTAKESPSTALTTLGIHPAPSPQLAY
>CP032698.1|AYG82952.1|5756965_5758030_-|dTDP-glucose-4,6-dehydratase
MTHPGTDKNGTDENGTEKNGTEKSGMNKILVTGGAGFIGSHYVRTLLDGGYEGYESAEVTVLDKLTYAGNRDNLPASHPRLAFVEGDICDLELLLELFPGHDAVVHFAAESHVDRSLESAAEFIATNVGGTQNVMEAALRAGVQRVVHVSTDEVYGSIDEGSWTEEWPLLPNSPYAASKAGSDLITRAYWRTHGLNVSITRCSNNYGPYQHPEKLIPRFVTNLLEGETVPLYGEGANIREWLHVDDHCRAIQLVLTKGRAGEIYNVGGGNEQTNRQITERLLELTGNDWSKVVRVADRKGHDLRYSLSEAKIAEELGYAPRISFEDGLAETAAWYRDNPGWWKAVKHAPQEGQK
>CP032698.1|AYG82953.1|5758026_5759094_-|Glucose-1-phosphate-thymidylyltransferase
MKALVLSGGTGSRLRPFSYSMPKQLIPIANKPVLERVLDNIRDLGVTEIGIIVGNHVEEIAEALGDGSRLGVEITYIPQESPKGLAQCVQLAQDFLGDDDFVMYLGDNMLPEGITEAAAEFHALRPAAQVLVAQVEDPRAFGVAEVDATGVVERLVEKPPVPRSNLALIGVYFFTPAIHEAVDSIVPSARGELEITDAIQWLVTNGSTVRAQEYRGYWKDTGRVEDVLECNQMLLDGIERRVDGEVDDQSVLIGAVVVEAGARITRSFVEGPVVIGAGTVLEDSHVGPHTSIGRDCVLSGTHLDYSIALDGATISAVRGLHGSLLGRSAAVTGIDLASRHHRLVVGDHTRVEVAA
>CP032698.1|AYG82954.1|5759203_5759779_-|FMN-reductase-(NADPH)
MATILAVSGSPSPVSSTHQVLTLAADRLADRGHRVETLAVRTLPAAELLRADAHHPQLAEAADQFARADAIVLATPVYKAGYSGLLKSFLDVLPQFALEGKVVLPLATGGSLAHVLALDYGLRPVLMSMKPRAVSESFFVHAGGIRKGPGGFAGLEPDTEALLHEATDTFAGLVESLTQAALSSVRLVPAA
>CP032698.1|AYG82955.1|5759844_5760987_-|Alkanal-monooxygenase-alpha-chain
MNADSRQTGSHGADGSAGERPLDFGVFFFAAVGDRAEETYRLMLDAARRADELGFGFVSTPERHFHRFGGAFPNPAVTSAAIAAVTSRIQIRAGSVVTPLHPAARIVEDFAMVDGISGGRVAISVGSGWNVNDFVIAPEKYETRREQMIKDVTDIRTAWRTGHWTGPNPLGVETTLPVFPRPVQDDLSVWVTASRSEGTFREAGRLGCNILTHLENQDVESLGDKIALYRSARAEAGWDGPGKVTVMMHTYVADDAATAREVGGGALRDYLLSAIDLEALAVEAGGRMSGNKQGREVLSAVKAQRKLAELGVNRYLSGNSLIGSVEECTETARRVRAAGVDEIACLVDFVADPRLVLASLERVAAVRREAARAAEPVLAA
>CP032698.1|AYG82956.1|5761523_5763044_+|Plipastatin-synthase-subunit-D
MTTQTLVAADTGTDTVHGLLAAAVAARPDAPAVRDASGVWTYAELDAWSRAYADWLTAQGVGHADRILVRVGNTREFTALMFGALRRGIAFVPVNPAMKRFHLNTVVPDCDPVLVIGQDAQDTAILRKLTGRPVFELDVVRRGAEALYDASLAADEAPVAPDDLGLLIYTSGSTSAPKAVVSTHAPIVFAARAIQARLDYREDDVVLVAVPVSFDYGLYQILLSVIAGAQVVLTSPDRHVRLLSTLHEYGVTVVPLVPSLGEMLLTLAKRDRREAPPVRLFTNTGAALTGPVIAQLRAAFPKAQVSPMFGTTECKRITVLEPDGDLVRPGSVGRALDGTEVLILDDDGRLLPSGTVGEICVRGPHIMTGYWQAPEQTALRFRPDPVTGETTLHTGDYGHLDAYGHLYFEGRRDDLFKRKGVRMGTLEIETAALDIEGVTAAAALAPAEGQDLTLYAVTELSADEVLAQLTERLEAAKVPAACHLLDALPLTPNGKTDKQRLRREQK
>CP032698.1|AYG82957.1|5763081_5763345_+|D-alanine--poly(phosphoribitol)-ligase-subunit-2
MTTTDVSWDAGFEQLLTSVLPRVTSPLDPALDLKAVGLDSMATIELLVRLEDQYDLEIPEGQLTGATFATPGALWAVLAAQRAGARA
>CP032698.1|AYG82958.1|5763404_5763497_+|hypothetical-protein
MSHLIIGLAVTVVVCLVIKFGGDALKKRRG
>CP032698.1|AYG82959.1|5764217_5767118_-|Multidrug-resistance-protein-3
MSTDVTAGAASGTATEKPAALKEAKEAKEKKPNPYGMSDVKVLVFIACAMAIMTLALLDGSIISSAVLPIVRDLDPAHGIDRFPWLITAYLLAATAAQPLYGRLSDSYGPRRVYLAALATFLAGSALCATAGSLTQLIVFRAVQGLGGGGLMSMTLIVIATLYPPKSRAGRSNAGGALIAAGIIAGPMIGGPLSENLSWRWIFLFNVPVAGLALVGVAWALRLPVKGTRQKVDILGSVLIAAATCALLLGVKEYGESHSFSGPVLPYFYGGVLMAGGFVTRQLKAADPLMPLTLFKDKVFRPAAILQFVGGFALLSLPVFFINYLNIVRGVSLDAVGLHLIPLAVGVVLVFLGWGKFIARTGKCKSVLVATTATATASVAGLGLTVTDAPVWQLDVLLLLLGVGLGGVTSIALFMTQSAASADQLGVVTTTSRFATMLGTTIGGTVLGAVLSARFASAAGASGIKDPDTAAAQLAGLDAIHRHLVRDAFAHATSTLLLTAAGLLLIALVTALVMKDVDVNALAAAAEAEADQPTGATPSRLNRLNRLNRPNQLNRLNGLNRLSRPKRPPERPRRTTTMRVLMLSTPFPTHFTPMVPLAWALRGAGHEVTVAAQPDVTDAARAAGISAVDIGDRFHGLDVLQRHLPDGVRPLELMGPTPPEKMAGTTKLWETHARYLVSSYLEFARGWGPDLIVSEQMELAGQLVAGALGIPSVQHRWGVDPLSGPSRASARNFLYGTAERLGLDGLPDPTLLLDPCPPALRHPSAAPGAPIGYVPFNGTGTVPDWLHQPAADGVRRVVVCLGRQTLVLNGTGLYRSIIAAFEGLENVEGVVTADAAFHAGFGQLPANVKVVEPVPLNLFLRDCDAVIHHGGANTTLTACSFGLPQVVLPQIVDQFASAELLAAAGAARVLGEAAPQNDSAQVREAIRDVLDDPRYLKCAGELGADMAEMPSPAGVVGDLERLVAAA
>CP032698.1|AYG82960.1|5767114_5768284_-|L-demethylnoviosyl-transferase
MRVLIIATPVDTHFLPMLPLVRALTGAGHDVLVAGQPDVTGPAEAAGLTTATFGEAFHYQDLRRGRRPEGLRPLEVVGRPPAQQIDGAAQMWRNHAPYFLYDYLELAREWRPDLVLGDHMEFAGPVIAEVLGVPSVWHRWGTAPTSAFMLGQTRMWLGPLCERLGLDSVPEPDLTLDPAPPTLASTEAPPARPIRPEPHTGDGTPWTYTSAPGRRVAVALGGYTLDLDGAPLLRRVLDALAAAGGVEAVVSAAPRHRPAIGALPDGMTYTERTEPGLLFAGADLVVHHGGPGSTLAAAAFGVPQLVLPQLDETFIAGDRVAAAGAGISLDTAELQNDDAQLAYATTALLTEPRYREGARRLRAEVEAMPTPADTVTLLEQLTTRQEVLA

Crispr_ID: CP032698_77

• CRISPR_ID: CP032698_77
• CRISPR_location: 5941563-5941756
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP032698_77

Consensus_repeat	Method
TT----------------GCGCAGTTCCCCGCGCCCCTAAA	PILER-CR

spacers of CP032698_77

>77.1|5941588|31|CP032698|PILER-CR
CCCTCTCGACCCTGCGAGCCGTGGCCGCTTC
>77.2|5941644|31|CP032698|PILER-CR
CCCCCGGTCATGTGCGGGCCGTGGTCGTTTT
>77.3|5941700|32|CP032698|PILER-CR
GCCCGTGTTCGTCCGCGGGCTGTGGTCGCGTC

CRISPR arrays and Neighbor proteins around CP032698_77

CRISPR arrays

The CRISPR arrays of CP032698_77

>merge|CP032698|77|5941563-5941756|PILER-CR
TTGCGCAGTTCCCCGCGCCCCTAAACCCTCTCGACCCTGCGAGCCGTGGCCGCTTCCCGCGCAGTTCCCCGCGCCCCTAACCCCCCGGTCATGTGCGGGCCGTGGTCGTTTTTTGCGCAGTTCCCCGCGCCCCCAAAGCCCGTGTTCGTCCGCGGGCTGTGGTCGCGTCTTGCGCAGTTCCTCGCGCCCCTTAA

>CP032698|77|20|5941563-5941756|PILER-CR
TTGCGCAGTTCCCCGCGCCCCTAAA	CCCTCTCGACCCTGCGAGCCGTGGCCGCTTC
CCGCGCAGTTCCCCGCGCCCCTAAC	CCCCCGGTCATGTGCGGGCCGTGGTCGTTTT
TTGCGCAGTTCCCCGCGCCCCCAAA	GCCCGTGTTCGTCCGCGGGCTGTGGTCGCGTC
TTGCGCAGTTCCTCGCGCCCCTTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83104.1|5938207_5938846_-|HTH-type-transcriptional-regulator-TtgR	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG83101.1|5934602_5935517_-|HTH-type-transcriptional-regulator-GltC	unknown	unknown	gnl|CDD|176115
CP032698.1|AYG83097.1|5930828_5931857_+|Putative-NADP-dependent-oxidoreductase-YfmJ	unknown	unknown	gnl|CDD|176190
CP032698.1|AYG83109.1|5943133_5943493_-|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG83108.1|5942684_5943182_-|hypothetical-protein	unknown	unknown	gnl|CDD|376573
CP032698.1|AYG83105.1|5939016_5941464_+|Thermostable-beta-glucosidase-B	unknown	unknown	gnl|CDD|224389
CP032698.1|AYG83115.1|5948121_5949039_-|Malonyl-CoA-acyl-carrier-protein-transacylase	unknown	unknown	gnl|CDD|223408
CP032698.1|AYG83111.1|5944876_5945371_+|hypothetical-protein	unknown	unknown	gnl|CDD|378644
CP032698.1|AYG83110.1|5943655_5944549_-|hypothetical-protein	unknown	unknown	gnl|CDD|238870
CP032698.1|AYG83113.1|5946797_5947046_-|Meromycolate-extension-acyl-carrier-protein	unknown	unknown	gnl|CDD|179197
CP032698.1|AYG83102.1|5935614_5936385_+|2-hydroxy-3-oxopropionate-reductase	unknown	unknown	gnl|CDD|224995
CP032698.1|AYG83100.1|5933573_5934578_+|Sulfate-transporter-CysZ	unknown	unknown	gnl|CDD|225528
CP032698.1|AYG83098.1|5932039_5932465_+|Organic-hydroperoxide-resistance-protein-OhrB	unknown	unknown	gnl|CDD|274649
CP032698.1|AYG83112.1|5945456_5946719_-|3-oxoacyl-[acyl-carrier-protein]-synthase-2	unknown	unknown	gnl|CDD|274452
CP032698.1|AYG83096.1|5930230_5930653_-|HTH-type-transcriptional-regulator-MhqR	unknown	unknown	gnl|CDD|197670
CP032698.1|AYG83107.1|5942214_5942574_-|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG83106.1|5941765_5942263_-|hypothetical-protein	unknown	unknown	gnl|CDD|376573
CP032698.1|AYG83099.1|5932491_5933484_+|Proline-iminopeptidase	unknown	unknown	gnl|CDD|130316
CP032698.1|AYG83114.1|5947114_5948110_-|3-oxoacyl-[acyl-carrier-protein]-synthase-3	unknown	unknown	gnl|CDD|237245
CP032698.1|AYG83103.1|5936893_5938138_-|Pyrrolidone-carboxylate-peptidase	unknown	unknown	gnl|CDD|224950

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83104.1|5938207_5938846_-|HTH-type-transcriptional-regulator-TtgR	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.35709e-15
CP032698.1|AYG83101.1|5934602_5935517_-|HTH-type-transcriptional-regulator-GltC	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.28714e-46
CP032698.1|AYG83097.1|5930828_5931857_+|Putative-NADP-dependent-oxidoreductase-YfmJ	gnl|CDD|176190	cd05288, PGDH, Prostaglandin dehydrogenases. Prostaglandins and related eicosanoids are metabolized by the oxidation of the 15(S)-hydroxyl group of the NAD+-dependent (type I 15-PGDH) 15-prostaglandin dehydrogenase (15-PGDH) followed by reduction by NADPH/NADH-dependent (type II 15-PGDH) delta-13 15-prostaglandin reductase (13-PGR) to 15-keto-13,14,-dihydroprostaglandins. 13-PGR is a bifunctional enzyme, since it also has leukotriene B(4) 12-hydroxydehydrogenase activity. These 15-PGDH and related enzymes are members of the medium chain dehydrogenase/reductase family. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES.	0
CP032698.1|AYG83109.1|5943133_5943493_-|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.67438e-21
CP032698.1|AYG83108.1|5942684_5943182_-|hypothetical-protein	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.86597e-11
CP032698.1|AYG83105.1|5939016_5941464_+|Thermostable-beta-glucosidase-B	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	2.43074e-60
CP032698.1|AYG83115.1|5948121_5949039_-|Malonyl-CoA-acyl-carrier-protein-transacylase	gnl|CDD|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	7.17163e-78
CP032698.1|AYG83111.1|5944876_5945371_+|hypothetical-protein	gnl|CDD|378644	pfam11343, DUF3145, Protein of unknown function (DUF3145). This family of proteins with unknown function appear to be restricted to Actinobacteria.	1.69441e-94
CP032698.1|AYG83110.1|5943655_5944549_-|hypothetical-protein	gnl|CDD|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	6.83854e-29
CP032698.1|AYG83113.1|5946797_5947046_-|Meromycolate-extension-acyl-carrier-protein	gnl|CDD|179197	PRK00982, acpP, acyl carrier protein; Provisional.	2.76706e-27
CP032698.1|AYG83102.1|5935614_5936385_+|2-hydroxy-3-oxopropionate-reductase	gnl|CDD|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	3.31267e-48
CP032698.1|AYG83100.1|5933573_5934578_+|Sulfate-transporter-CysZ	gnl|CDD|225528	COG2981, CysZ, Uncharacterized protein involved in cysteine biosynthesis [Amino acid transport and metabolism].	7.24659e-26
CP032698.1|AYG83098.1|5932039_5932465_+|Organic-hydroperoxide-resistance-protein-OhrB	gnl|CDD|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	4.81345e-73
CP032698.1|AYG83112.1|5945456_5946719_-|3-oxoacyl-[acyl-carrier-protein]-synthase-2	gnl|CDD|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
CP032698.1|AYG83096.1|5930230_5930653_-|HTH-type-transcriptional-regulator-MhqR	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	6.67129e-14
CP032698.1|AYG83107.1|5942214_5942574_-|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.67438e-21
CP032698.1|AYG83106.1|5941765_5942263_-|hypothetical-protein	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.86597e-11
CP032698.1|AYG83099.1|5932491_5933484_+|Proline-iminopeptidase	gnl|CDD|130316	TIGR01249, Putative_proline_iminopeptidase, proline iminopeptidase, Neisseria-type subfamily. This model represents one of two related families of proline iminopeptidase in the alpha/beta fold hydrolase family. The fine specificities of the various members, including both the range of short peptides from which proline can be removed and whether other amino acids such as alanine can be also removed, may vary among members.	4.89799e-93
CP032698.1|AYG83114.1|5947114_5948110_-|3-oxoacyl-[acyl-carrier-protein]-synthase-3	gnl|CDD|237245	PRK12879, PRK12879, 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed.	5.84974e-161
CP032698.1|AYG83103.1|5936893_5938138_-|Pyrrolidone-carboxylate-peptidase	gnl|CDD|224950	COG2039, Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) [Posttranslational modification, protein turnover, chaperones].	3.11364e-05

Protein sequences

>CP032698.1|AYG83105.1|5939016_5941464_+|Thermostable-beta-glucosidase-B
MAGTPVSTPDYSEVVEAALGRLDLEAKARLLAGQDMWSLPALPEIGLGSLVMSDGPIGVRGVRWSADDPSIALPSPTALAATWDPDLARRAGVLLAQEARRKGVHVLLAPTVNLHRSPLGGRHFECYSEDPCLTGEIASGYVGGVQSGGVGTTVKHFVANDAETDRFTVDNVVAPRPLRELYLAPFETIVENAHPWGIMSAYNQVNGTTMTEHHHLQSEVLRGEWGFDGFIVSDWMAARSTVGDILGGLDVAMPGPRTVYGDALAAAVRKGEVDESVVDDAVRNVLRLAARVGILDGVDGAVTELPAALDGPALAREVARRSFVLVRNEGGALPVDPDRIGTVALSGAAARDARVLGGGSATVFPEHVVSPLDGLTAALPAGALTYSVGADPSDELAPADQGFTLRAVCHDADGNVLGAGSLPSGQVQWIGDDLPAGVTHEALHSVEVTGTFTPRESGEHTFGTRGIGAFALTVDGRVLWEGSQSPRDGADPFEAFFGAPAERGRVHLTEGETVEVSLLHTVQGPAGAPLTAVMFSLTHLGPRRDPDELIAEAVEAARAAELAVVVVATTDRVESEGFDRRDLRLPGRQDDLVRAVAAVNPRTVVIVNSGSPVELPWRESVAAVLLSWFPGQEGGAALADVLLGHAEPGGRLPTTWPAALADAPVTEVRPTRGQLPYSEGLFIGYRAYDRHGVTPAYPFGHGLGYTTWEYESLEVTPTHAKVRVRNTGARAGRETVQIYLAPVADPVERPRRWLAGFASVAADAGVAVEVDIPLRGRAFEIWDEGEGAWRFVPGPYEVRACHSLEDVRLAAVLGI
>CP032698.1|AYG83104.1|5938207_5938846_-|HTH-type-transcriptional-regulator-TtgR
MARTRSARSEERRADILRAALEVIAERGYRGSSLGAVAERVGLTQQGLLHYFPTKEALLLAVLEERDQWDTGGRRATPGGWRLELLASLVEYNAMRPGIVGTFSALLGESVTEEHPARPFFTRRYAQVRQEMAGVLRAEFGDLLPGGLTPERAAPLLAAVMDGLQFQWLLDPDAVDMADAFRDFMTLLYGPEGPGGPEGPGGSDGSDGSDGS
>CP032698.1|AYG83103.1|5936893_5938138_-|Pyrrolidone-carboxylate-peptidase
MRRRVRVARLGCALAAMTFCTLLGPAPAQAATGPGQATVEEQRLERPAAKEILERGGFAGVAPGFARELAGARSYEAARRLVEREGSGLWRRAVDRVQGRGPAGGDLSRDDDRPLYWARLGLTRELRLWQPEFTLTQASRAALLDRLEQTSRGQTSVNYPAGGGYKRILLTGFDPFTLDRDIRISNPSGATALALDGTWIRTADGQLARIETMTFPVRWQDFADGVVERALTPVLPKVDAFTTVSQGRVGRIDVERFNGAWRGGFPDNDNASSTGPVPVSDPASQPQWTRTTLPYQDIVAGATGRFPVYDHTDVTEIPAGGSEPVDRPDGPTPGSTARAGGGGDYLSNEIAYRATLLRDRLGLSVPGGHVHAPVLEFGPANTDPATGSVTDPQFVRNRLDIVAQIRAIIRAATR
>CP032698.1|AYG83102.1|5935614_5936385_+|2-hydroxy-3-oxopropionate-reductase
MGTPMATRLLDAGHSLTVWNRTAARAEGLAARGAAVAATPGDAVRCADVVISMLADPAAVAAVVTSAAPQLRPGTHWIEMSTIGPDAVRDLAGLLPEGVTLLDAPVLGSVDKAAAGELGVLVGGEADGVEKVLGALGTVTRCGPLGSAAALKLVVNTALVGGVVVVAEALALADRLGVPAAMAERTLLASALGGAARRALATEAAFATALAAKDLALATATAPLPVLGAVHDRLGAYPELAARDLARAADRIRAGG
>CP032698.1|AYG83101.1|5934602_5935517_-|HTH-type-transcriptional-regulator-GltC
MPVTHSLYEVFLRVAADRSFTSAAASLGYTQSAVSRQVQSLETELGARLFDRLPRGVRLTEAGRVLLPHAEAVRDRLTAARAELDALRTLDGGLLRIGAFATADAALLPRALAAFRALRPGVSVARTEGPSAKHLRLLAAGDLDVAVVSDTAGQSLDGCTLHHLLDEPMYVALPQGHRLAGRGEVRLSELADEEWVAGSARPEDTLLRSAAEAGFRPRTAYVVQDWIAKQGFVAAGLGVTLLPALAADSVRADITLAGVHPEDVPRRAVYAATPRGLTHSPATSAFLAQLRRSARELMDDVAAR
>CP032698.1|AYG83100.1|5933573_5934578_+|Sulfate-transporter-CysZ
MRDLGAGFGYLVKGQRWAAGHGRSLGVGLLPGLITLVLYVGALIGLAYGADDFVGWATPFADDWSSPWLGLFRGCLTALVFALGLFLAVISFTAVTLLVGQPFYEKLSADVDRSESGGAAPESGLSLGRELWISARDSLRILIRVGCYGVLLFALGFVPVIGQSVIPAIGFCVTGFFLTEELTAVALQRRGMELRPRLALLRSRRLLTLGFGVPLAVAFVVPLVAIFLMPGAVAGATLMVRDLLDESDADDQTRGADDETRGGDGETRRAGDETRRADGETRRAGDETRRVGGEPRRVGGEPRRVGGGLRRADGQSPGAGAMGDGDPARTPPAL
>CP032698.1|AYG83099.1|5932491_5933484_+|Proline-iminopeptidase
MARSFAMLGRMTFPETAPYDHGTLDTGDGNLVHWEVCGNPGGKPAVVVHGGPGSGAGPSWRRYFDPARYRVVLFDQRGCGRSTPSAGEATTDLATNTTHHLMADMEQLREHLGIAKWLVFGGSWGATLGLAYAQAHPDRVSEVVLFSIATTSRAEVDWITEGVGGHFPEAWAEFRDAARPGEGERLVDAYARLLADPDPAVREEAARNWCRWEDTHVRAPGARLPESFGGSRYADPAFRMTFARLVTHYWRHAAWLEDGQLLRGASELGKIPGVLITGGQDLSSPPDPARALADRWPGCELLAIDDAGHGLSHADMGAAAQDALDRFARS
>CP032698.1|AYG83098.1|5932039_5932465_+|Organic-hydroperoxide-resistance-protein-OhrB
MSIQKSEVLYTAVATAENGRDGRVSTDDGQLDVVVNPPKEMGGSGAGTNPEQLFAAGYSACFQGALGVVARNEKADISGSTVTAHVGIGKNDDGFGIYVEITATIPNVDRATAQDLIEKAHQVCPYSKATRGNITVNLAVA
>CP032698.1|AYG83097.1|5930828_5931857_+|Putative-NADP-dependent-oxidoreductase-YfmJ
MATSSALPATSREWHLVARPNGWPVPSDFALRETPVAEPAPGRILVRNLFMSVDPYMRGRMNDVKSYVPPFQLERPMDGGAVGEVIASNDDGFAVGDQVLHGLGWREYADVDARHATKVDGALAPLSAYLGVLGMPGLTAYAGLLEVASFKEGDAVFVSGAAGAVGSQVGQIARLKGASRVIGSAGSDEKVKWLVEELGFDAAFNYKNGPVLDQLRAAAPDGIDVYFDNVGGEHLEAAISALNVHGRATICGMIAGYNDTEPTPGPRNMAMVIGKRLRLQGVLVGDHYGMQQQFVGEVAGWLASGELKYSETVVDGIENGVDAFLGMLRGANTGKMVVSLGE
>CP032698.1|AYG83096.1|5930230_5930653_-|HTH-type-transcriptional-regulator-MhqR
MAPRTDPLSLEVIELIGTVVARYYEEYERAAAEHSLTGAQARVLGLLSLEPMPMRRIAQKLKCEPSNITGIVDRLEARGLVERRPDPLDRRVKLAAPTADGLATAADLRASLNFAREPLAELSTRERTVLRDLLKRMLGD
>CP032698.1|AYG83106.1|5941765_5942263_-|hypothetical-protein
MRDRLGEHAGPEKGDLTGPNPVDRGKYGSKIHLITERSGLPISVGISGANLHDSQALIPLVKGIPPIRSRRGPRRRKPSKLHADKGYDYAHLRQWLRERGITHRIARKGVESSQRLGRHRWTVERTMAWLAGCRRLHRRYERKADHFLAFTSIACTLICYRRLAK
>CP032698.1|AYG83107.1|5942214_5942574_-|hypothetical-protein
MVGIVERLVPDELWELFQRVVPEAPSRPQGGGRRRHGDREVLAAIVFVATSGCTWQQLPSASFGPSGATAHRRFSEWSKARVWAKLHRLVLDELGARGELDWSRCAIDSVNMRALKRGT
>CP032698.1|AYG83108.1|5942684_5943182_-|hypothetical-protein
MRDRLGEHAGPEKGDLTGPNPVDRGKYGSKIHLITERSGLPISVGISGANLHDSQALIPLVKGIPPIRSRRGPRRRKPSKLHADKGYDYAHLRQWLRERGITHRIARKGVESSQRLGRHRWTVERTMAWLAGCRRLHRRYERKADHFLAFTSIACTLICYRRLAK
>CP032698.1|AYG83109.1|5943133_5943493_-|hypothetical-protein
MVGIVERLVPDELWELFQRVVPEAPSRPQGGGRRRHGDREVLAAIVFVATSGCTWQQLPSASFGPSGATAHRRFSEWSKARVWAKLHRLVLDELGARGELDWSRCAIDSVNMRALKRGT
>CP032698.1|AYG83110.1|5943655_5944549_-|hypothetical-protein
MQDSRRSRRVRAAAALLAASALALTAGCESGGGSSAASPAASKKPSPSPSPAWNRSPASIAAIGDSITRGFDACQVLADCPEVSWATGSDPAVDSLAVRLLGPAAPAHSWNYAKTGARMADLPAQMERAAAQHPGLVTVMTGANDACRDDVAAMTPVASFRADFETSLRKLRAVSPTSQVYVSSVPDLKRLWSTGRGSPLGKQIWKLGICRSMLADADDLGPAATRRREAVYERVVAYNEVLRGVCAGDRRCRYDGGAVFAYAFGGTQLSPWDWFHPSRDGQARLAEIAYAQVTAPS
>CP032698.1|AYG83111.1|5944876_5945371_+|hypothetical-protein
MTTRGVLYVHSAPRALCPHVEWAVAGVLGVRVQLDWIRQPASPGTWRAEFSWRGEPGTASKLASALRGWHLLRFEVTAEPCATAEGERYSATPDLGIFHAVTGIHGDILIPEDRLRAALARSVQGETDLEAEIAKLLGKPWDDELEPFRYAGEGAPVRWLHQVV
>CP032698.1|AYG83112.1|5945456_5946719_-|3-oxoacyl-[acyl-carrier-protein]-synthase-2
MSSTNRTVVVTGIGATTPLGGDTASTWEGLLAGRSGVRPLEGERFAELPVRIAAPAAVDPGEVLPRPLARKLDRSAQFALIAAKEAWADAGFTAPAGDEAGIAPERLGTVIASGIGGVTTLLDQYDVLKEKGVRRVSPHTVPMLMPNGPSANVGLEVNARAGVHTPVSACASGAEAIGYAVEMIRTGRADVVVAGGTEAAIHPLPIAAFANMMAMSKNNDHPEHASRPYDKGRDGFVLGEGAGVVILESAEHAAKRGARVYCEVLGQGLSADSHHIAQPEPTGRGVAAAVQNLLDSTDLKPAEVVHLNAHATSTPQGDIAEIKALRKVLGDDLDHVAISATKSMTGHLLGGAGGIETVATVLALYHRLAPPTINIEELDDEVDPALVSSEVRKLPEGSISAINNSFGFGGHNVVLAFRSV
>CP032698.1|AYG83113.1|5946797_5947046_-|Meromycolate-extension-acyl-carrier-protein
MAATQEEILEGLAEIVNEIAGIPVEDVQLDKSFTDDLDVDSLSMVEVVVAAEERFDVKIPDEDVKNLKTVGDAAGYILKHQA
>CP032698.1|AYG83114.1|5947114_5948110_-|3-oxoacyl-[acyl-carrier-protein]-synthase-3
MSKIRPSQGAPYARILGVGGYRPVRVVPNEVILETIDSSDEWIRSRSGIATRHWASADETVSAMSIEASGKAIADSGISADQIGAVIVSTVSHFKQTPAVATEIADKLGTGKAAAFDISAGCAGFGYGLTLAKGMIVEGSAKYVLVIGVERLSDLTDLQDRATAFLFGDGAGAVVVGPSDEPAIGPTIWGSEGDKSETIKQTVPWTEYDSSGKFPAITQEGQAVFRWAVFEMAKVAQQALDAAGISPDDLDVFIPHQANMRIIDSMVKTLKLPDHVTVARDVETTGNTSAASIPLAMERLLATGQAKSGDTALVIGFGAGLVYAATVVTLP
>CP032698.1|AYG83115.1|5948121_5949039_-|Malonyl-CoA-acyl-carrier-protein-transacylase
MLVLVAPGQGAQTPGFLTPWLDLPGAADRLAAWSDAIGLDLVHYGTQADADAIRDTAVAQPLLVAAGLLSASALGDFAPGAVAGHSVGEITATAFAGVLSEEAALGFVRKRGLGMAEAAAVTPTGMAALLGGAPADVLPHLEKLGLTPANVNGAGQIVAAGTAEQLAALEADKPEGVRRVVALKVAGAFHTHHMNPAVAALDEAAKSLAIADPKLTYVSNADGKTVASGQDIVARLVNQVSNPVRWDLCMETFTELGATALVELCPGGTLTGLAKRAMPGVKTVALKTPADLDAARALIAEHASA

Crispr_ID: CP032698_78

• CRISPR_ID: CP032698_78
• CRISPR_location: 5943544-5943646
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_78

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGG	CRISPRCasFinder

spacers of CP032698_78

>78.1|5943568|55|CP032698|CRISPRCasFinder
AAGGCCCGGGCCATCCAACCCTGCGCCTACGGGCGGGTGGGTGGGCAAAGGGCCT

CRISPR arrays and Neighbor proteins around CP032698_78

CRISPR arrays

The CRISPR arrays of CP032698_78

>merge|CP032698|78|5943544-5943646|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGAAGGCCCGGGCCATCCAACCCTGCGCCTACGGGCGGGTGGGTGGGCAAAGGGCCTCGGGGTTTGGGGCGGAGCCCCAGG

>CP032698|78|57|5943544-5943646|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGG	AAGGCCCGGGCCATCCAACCCTGCGCCTACGGGCGGGTGGGTGGGCAAAGGGCCT
CGGGGTTTGGGGCGGAGCCCCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83104.1|5938207_5938846_-|HTH-type-transcriptional-regulator-TtgR	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG83101.1|5934602_5935517_-|HTH-type-transcriptional-regulator-GltC	unknown	unknown	gnl|CDD|176115
CP032698.1|AYG83110.1|5943655_5944549_-|hypothetical-protein	unknown	unknown	gnl|CDD|238870
CP032698.1|AYG83116.1|5949130_5950327_-|Proline-responsive-transcriptional-activator-PutR	unknown	unknown	gnl|CDD|379258
CP032698.1|AYG83109.1|5943133_5943493_-|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG83105.1|5939016_5941464_+|Thermostable-beta-glucosidase-B	unknown	unknown	gnl|CDD|224389
CP032698.1|AYG83115.1|5948121_5949039_-|Malonyl-CoA-acyl-carrier-protein-transacylase	unknown	unknown	gnl|CDD|223408
CP032698.1|AYG83111.1|5944876_5945371_+|hypothetical-protein	unknown	unknown	gnl|CDD|378644
CP032698.1|AYG83117.1|5950418_5951087_+|Putative-quercetin-2,3-dioxygenase	unknown	unknown	gnl|CDD|380375
CP032698.1|AYG83118.1|5951126_5951945_-|D-alanyl-D-alanine--carboxypeptidase/endopeptidase-AmpH	unknown	unknown	gnl|CDD|365903
CP032698.1|AYG83102.1|5935614_5936385_+|2-hydroxy-3-oxopropionate-reductase	unknown	unknown	gnl|CDD|224995
CP032698.1|AYG83113.1|5946797_5947046_-|Meromycolate-extension-acyl-carrier-protein	unknown	unknown	gnl|CDD|179197
CP032698.1|AYG83112.1|5945456_5946719_-|3-oxoacyl-[acyl-carrier-protein]-synthase-2	unknown	unknown	gnl|CDD|274452
CP032698.1|AYG83103.1|5936893_5938138_-|Pyrrolidone-carboxylate-peptidase	unknown	unknown	gnl|CDD|224950
CP032698.1|AYG83107.1|5942214_5942574_-|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG83119.1|5952114_5952576_+|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|133384
CP032698.1|AYG83106.1|5941765_5942263_-|hypothetical-protein	unknown	unknown	gnl|CDD|376573
CP032698.1|AYG83100.1|5933573_5934578_+|Sulfate-transporter-CysZ	unknown	unknown	gnl|CDD|225528
CP032698.1|AYG83114.1|5947114_5948110_-|3-oxoacyl-[acyl-carrier-protein]-synthase-3	unknown	unknown	gnl|CDD|237245
CP032698.1|AYG83108.1|5942684_5943182_-|hypothetical-protein	unknown	unknown	gnl|CDD|376573

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83104.1|5938207_5938846_-|HTH-type-transcriptional-regulator-TtgR	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.35709e-15
CP032698.1|AYG83101.1|5934602_5935517_-|HTH-type-transcriptional-regulator-GltC	gnl|CDD|176115	cd08423, PBP2_LTTR_like_6, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.28714e-46
CP032698.1|AYG83110.1|5943655_5944549_-|hypothetical-protein	gnl|CDD|238870	cd01832, SGNH_hydrolase_like_1, Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid. Myxobacterial members of this subfamily have been reported to be involved in adventurous gliding motility.	6.83854e-29
CP032698.1|AYG83116.1|5949130_5950327_-|Proline-responsive-transcriptional-activator-PutR	gnl|CDD|379258	pfam13556, HTH_30, PucR C-terminal helix-turn-helix domain. This helix-turn-helix domain is often found at the C-terminus of PucR-like transcriptional regulators such as Bacillus subtilis pucR and is likely to be DNA-binding.	7.02631e-18
CP032698.1|AYG83109.1|5943133_5943493_-|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.67438e-21
CP032698.1|AYG83105.1|5939016_5941464_+|Thermostable-beta-glucosidase-B	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	2.43074e-60
CP032698.1|AYG83115.1|5948121_5949039_-|Malonyl-CoA-acyl-carrier-protein-transacylase	gnl|CDD|223408	COG0331, FabD, (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism].	7.17163e-78
CP032698.1|AYG83111.1|5944876_5945371_+|hypothetical-protein	gnl|CDD|378644	pfam11343, DUF3145, Protein of unknown function (DUF3145). This family of proteins with unknown function appear to be restricted to Actinobacteria.	1.69441e-94
CP032698.1|AYG83117.1|5950418_5951087_+|Putative-quercetin-2,3-dioxygenase	gnl|CDD|380375	cd02910, cupin_Yhhw_N, Escherichia coli YhhW and YhaK and related proteins, pirin-like bicupin, N-terminal cupin domain. This family includes the N-terminal cupin domains of YhhW and YhaK, Escherichia coli pirin-like proteins with unknown function. YhhW is structurally similar not only to human pirin but also to quercitin 2,3-dioxygenase (quercitinase). Although the function of YhhW is not completely understood, YhhW and its human ortholog have quercitinase activity and are likely to play an important role in transcription and apoptosis. This N-terminal cupin domain of YhhW has a metal coordination site and is thought to have catalytic activity while the C-terminal cupin-like domain has diverged considerably and has closer alignment with C-terminal pirin. YhaK is found in low abundance in the cytosol of E. coli and is strongly up-regulated by nitroso-glutathione (GSNO). There are major structural differences at the N-terminus of YhaK compared with YhhW; YhaK lacks the canonical cupin metal-binding residues of pirins and may be involved in chloride binding and/or sensing of oxidative stress in enterobacteria. YhaK showed no quercetinase and peroxidase activity; however, reduced YhaK was very sensitive to reactive oxygen species (ROS). Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	4.15789e-47
CP032698.1|AYG83118.1|5951126_5951945_-|D-alanyl-D-alanine--carboxypeptidase/endopeptidase-AmpH	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	2.6342e-33
CP032698.1|AYG83102.1|5935614_5936385_+|2-hydroxy-3-oxopropionate-reductase	gnl|CDD|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	3.31267e-48
CP032698.1|AYG83113.1|5946797_5947046_-|Meromycolate-extension-acyl-carrier-protein	gnl|CDD|179197	PRK00982, acpP, acyl carrier protein; Provisional.	2.76706e-27
CP032698.1|AYG83112.1|5945456_5946719_-|3-oxoacyl-[acyl-carrier-protein]-synthase-2	gnl|CDD|274452	TIGR03150, fabF, beta-ketoacyl-acyl-carrier-protein synthase II. 3-oxoacyl-[acyl-carrier-protein] synthase 2 (KAS-II, FabF) is involved in the condensation step of fatty acid biosynthesis in which the malonyl donor group is decarboxylated and the resulting carbanion used to attack and extend the acyl group attached to the acyl carrier protein. Most genomes encoding fatty acid biosynthesis contain a number of condensing enzymes, often of all three types: 1, 2 and 3. Synthase 2 is mechanistically related to synthase 1 (KAS-I, FabB) containing a number of absolutely conserved catalytic residues in common. This model is based primarily on genes which are found in apparent operons with other essential genes of fatty acid biosynthesis (GenProp0681). The large gap between the trusted cutoff and the noise cutoff contains many genes which are not found adjacent to genes of the fatty acid pathway in genomes that often also contain a better hit to this model. These genes may be involved in other processes such as polyketide biosyntheses. Some genomes contain more than one above-trusted hit to this model which may result from recent paralogous expansions. Second hits to this model which are not next to other fatty acid biosynthesis genes may be involved in other processes. FabB sequences should fall well below the noise cutoff of this model. [Fatty acid and phospholipid metabolism, Biosynthesis].	0
CP032698.1|AYG83103.1|5936893_5938138_-|Pyrrolidone-carboxylate-peptidase	gnl|CDD|224950	COG2039, Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) [Posttranslational modification, protein turnover, chaperones].	3.11364e-05
CP032698.1|AYG83107.1|5942214_5942574_-|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.67438e-21
CP032698.1|AYG83119.1|5952114_5952576_+|putative-HTH-type-transcriptional-regulator	gnl|CDD|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	9.14448e-55
CP032698.1|AYG83106.1|5941765_5942263_-|hypothetical-protein	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.86597e-11
CP032698.1|AYG83100.1|5933573_5934578_+|Sulfate-transporter-CysZ	gnl|CDD|225528	COG2981, CysZ, Uncharacterized protein involved in cysteine biosynthesis [Amino acid transport and metabolism].	7.24659e-26
CP032698.1|AYG83114.1|5947114_5948110_-|3-oxoacyl-[acyl-carrier-protein]-synthase-3	gnl|CDD|237245	PRK12879, PRK12879, 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed.	5.84974e-161
CP032698.1|AYG83108.1|5942684_5943182_-|hypothetical-protein	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.86597e-11

Protein sequences

>CP032698.1|AYG83109.1|5943133_5943493_-|hypothetical-protein
MVGIVERLVPDELWELFQRVVPEAPSRPQGGGRRRHGDREVLAAIVFVATSGCTWQQLPSASFGPSGATAHRRFSEWSKARVWAKLHRLVLDELGARGELDWSRCAIDSVNMRALKRGT
>CP032698.1|AYG83108.1|5942684_5943182_-|hypothetical-protein
MRDRLGEHAGPEKGDLTGPNPVDRGKYGSKIHLITERSGLPISVGISGANLHDSQALIPLVKGIPPIRSRRGPRRRKPSKLHADKGYDYAHLRQWLRERGITHRIARKGVESSQRLGRHRWTVERTMAWLAGCRRLHRRYERKADHFLAFTSIACTLICYRRLAK
>CP032698.1|AYG83107.1|5942214_5942574_-|hypothetical-protein
MVGIVERLVPDELWELFQRVVPEAPSRPQGGGRRRHGDREVLAAIVFVATSGCTWQQLPSASFGPSGATAHRRFSEWSKARVWAKLHRLVLDELGARGELDWSRCAIDSVNMRALKRGT
>CP032698.1|AYG83106.1|5941765_5942263_-|hypothetical-protein
MRDRLGEHAGPEKGDLTGPNPVDRGKYGSKIHLITERSGLPISVGISGANLHDSQALIPLVKGIPPIRSRRGPRRRKPSKLHADKGYDYAHLRQWLRERGITHRIARKGVESSQRLGRHRWTVERTMAWLAGCRRLHRRYERKADHFLAFTSIACTLICYRRLAK
>CP032698.1|AYG83105.1|5939016_5941464_+|Thermostable-beta-glucosidase-B
MAGTPVSTPDYSEVVEAALGRLDLEAKARLLAGQDMWSLPALPEIGLGSLVMSDGPIGVRGVRWSADDPSIALPSPTALAATWDPDLARRAGVLLAQEARRKGVHVLLAPTVNLHRSPLGGRHFECYSEDPCLTGEIASGYVGGVQSGGVGTTVKHFVANDAETDRFTVDNVVAPRPLRELYLAPFETIVENAHPWGIMSAYNQVNGTTMTEHHHLQSEVLRGEWGFDGFIVSDWMAARSTVGDILGGLDVAMPGPRTVYGDALAAAVRKGEVDESVVDDAVRNVLRLAARVGILDGVDGAVTELPAALDGPALAREVARRSFVLVRNEGGALPVDPDRIGTVALSGAAARDARVLGGGSATVFPEHVVSPLDGLTAALPAGALTYSVGADPSDELAPADQGFTLRAVCHDADGNVLGAGSLPSGQVQWIGDDLPAGVTHEALHSVEVTGTFTPRESGEHTFGTRGIGAFALTVDGRVLWEGSQSPRDGADPFEAFFGAPAERGRVHLTEGETVEVSLLHTVQGPAGAPLTAVMFSLTHLGPRRDPDELIAEAVEAARAAELAVVVVATTDRVESEGFDRRDLRLPGRQDDLVRAVAAVNPRTVVIVNSGSPVELPWRESVAAVLLSWFPGQEGGAALADVLLGHAEPGGRLPTTWPAALADAPVTEVRPTRGQLPYSEGLFIGYRAYDRHGVTPAYPFGHGLGYTTWEYESLEVTPTHAKVRVRNTGARAGRETVQIYLAPVADPVERPRRWLAGFASVAADAGVAVEVDIPLRGRAFEIWDEGEGAWRFVPGPYEVRACHSLEDVRLAAVLGI
>CP032698.1|AYG83104.1|5938207_5938846_-|HTH-type-transcriptional-regulator-TtgR
MARTRSARSEERRADILRAALEVIAERGYRGSSLGAVAERVGLTQQGLLHYFPTKEALLLAVLEERDQWDTGGRRATPGGWRLELLASLVEYNAMRPGIVGTFSALLGESVTEEHPARPFFTRRYAQVRQEMAGVLRAEFGDLLPGGLTPERAAPLLAAVMDGLQFQWLLDPDAVDMADAFRDFMTLLYGPEGPGGPEGPGGSDGSDGSDGS
>CP032698.1|AYG83103.1|5936893_5938138_-|Pyrrolidone-carboxylate-peptidase
MRRRVRVARLGCALAAMTFCTLLGPAPAQAATGPGQATVEEQRLERPAAKEILERGGFAGVAPGFARELAGARSYEAARRLVEREGSGLWRRAVDRVQGRGPAGGDLSRDDDRPLYWARLGLTRELRLWQPEFTLTQASRAALLDRLEQTSRGQTSVNYPAGGGYKRILLTGFDPFTLDRDIRISNPSGATALALDGTWIRTADGQLARIETMTFPVRWQDFADGVVERALTPVLPKVDAFTTVSQGRVGRIDVERFNGAWRGGFPDNDNASSTGPVPVSDPASQPQWTRTTLPYQDIVAGATGRFPVYDHTDVTEIPAGGSEPVDRPDGPTPGSTARAGGGGDYLSNEIAYRATLLRDRLGLSVPGGHVHAPVLEFGPANTDPATGSVTDPQFVRNRLDIVAQIRAIIRAATR
>CP032698.1|AYG83102.1|5935614_5936385_+|2-hydroxy-3-oxopropionate-reductase
MGTPMATRLLDAGHSLTVWNRTAARAEGLAARGAAVAATPGDAVRCADVVISMLADPAAVAAVVTSAAPQLRPGTHWIEMSTIGPDAVRDLAGLLPEGVTLLDAPVLGSVDKAAAGELGVLVGGEADGVEKVLGALGTVTRCGPLGSAAALKLVVNTALVGGVVVVAEALALADRLGVPAAMAERTLLASALGGAARRALATEAAFATALAAKDLALATATAPLPVLGAVHDRLGAYPELAARDLARAADRIRAGG
>CP032698.1|AYG83101.1|5934602_5935517_-|HTH-type-transcriptional-regulator-GltC
MPVTHSLYEVFLRVAADRSFTSAAASLGYTQSAVSRQVQSLETELGARLFDRLPRGVRLTEAGRVLLPHAEAVRDRLTAARAELDALRTLDGGLLRIGAFATADAALLPRALAAFRALRPGVSVARTEGPSAKHLRLLAAGDLDVAVVSDTAGQSLDGCTLHHLLDEPMYVALPQGHRLAGRGEVRLSELADEEWVAGSARPEDTLLRSAAEAGFRPRTAYVVQDWIAKQGFVAAGLGVTLLPALAADSVRADITLAGVHPEDVPRRAVYAATPRGLTHSPATSAFLAQLRRSARELMDDVAAR
>CP032698.1|AYG83100.1|5933573_5934578_+|Sulfate-transporter-CysZ
MRDLGAGFGYLVKGQRWAAGHGRSLGVGLLPGLITLVLYVGALIGLAYGADDFVGWATPFADDWSSPWLGLFRGCLTALVFALGLFLAVISFTAVTLLVGQPFYEKLSADVDRSESGGAAPESGLSLGRELWISARDSLRILIRVGCYGVLLFALGFVPVIGQSVIPAIGFCVTGFFLTEELTAVALQRRGMELRPRLALLRSRRLLTLGFGVPLAVAFVVPLVAIFLMPGAVAGATLMVRDLLDESDADDQTRGADDETRGGDGETRRAGDETRRADGETRRAGDETRRVGGEPRRVGGEPRRVGGGLRRADGQSPGAGAMGDGDPARTPPAL
>CP032698.1|AYG83110.1|5943655_5944549_-|hypothetical-protein
MQDSRRSRRVRAAAALLAASALALTAGCESGGGSSAASPAASKKPSPSPSPAWNRSPASIAAIGDSITRGFDACQVLADCPEVSWATGSDPAVDSLAVRLLGPAAPAHSWNYAKTGARMADLPAQMERAAAQHPGLVTVMTGANDACRDDVAAMTPVASFRADFETSLRKLRAVSPTSQVYVSSVPDLKRLWSTGRGSPLGKQIWKLGICRSMLADADDLGPAATRRREAVYERVVAYNEVLRGVCAGDRRCRYDGGAVFAYAFGGTQLSPWDWFHPSRDGQARLAEIAYAQVTAPS
>CP032698.1|AYG83111.1|5944876_5945371_+|hypothetical-protein
MTTRGVLYVHSAPRALCPHVEWAVAGVLGVRVQLDWIRQPASPGTWRAEFSWRGEPGTASKLASALRGWHLLRFEVTAEPCATAEGERYSATPDLGIFHAVTGIHGDILIPEDRLRAALARSVQGETDLEAEIAKLLGKPWDDELEPFRYAGEGAPVRWLHQVV
>CP032698.1|AYG83112.1|5945456_5946719_-|3-oxoacyl-[acyl-carrier-protein]-synthase-2
MSSTNRTVVVTGIGATTPLGGDTASTWEGLLAGRSGVRPLEGERFAELPVRIAAPAAVDPGEVLPRPLARKLDRSAQFALIAAKEAWADAGFTAPAGDEAGIAPERLGTVIASGIGGVTTLLDQYDVLKEKGVRRVSPHTVPMLMPNGPSANVGLEVNARAGVHTPVSACASGAEAIGYAVEMIRTGRADVVVAGGTEAAIHPLPIAAFANMMAMSKNNDHPEHASRPYDKGRDGFVLGEGAGVVILESAEHAAKRGARVYCEVLGQGLSADSHHIAQPEPTGRGVAAAVQNLLDSTDLKPAEVVHLNAHATSTPQGDIAEIKALRKVLGDDLDHVAISATKSMTGHLLGGAGGIETVATVLALYHRLAPPTINIEELDDEVDPALVSSEVRKLPEGSISAINNSFGFGGHNVVLAFRSV
>CP032698.1|AYG83113.1|5946797_5947046_-|Meromycolate-extension-acyl-carrier-protein
MAATQEEILEGLAEIVNEIAGIPVEDVQLDKSFTDDLDVDSLSMVEVVVAAEERFDVKIPDEDVKNLKTVGDAAGYILKHQA
>CP032698.1|AYG83114.1|5947114_5948110_-|3-oxoacyl-[acyl-carrier-protein]-synthase-3
MSKIRPSQGAPYARILGVGGYRPVRVVPNEVILETIDSSDEWIRSRSGIATRHWASADETVSAMSIEASGKAIADSGISADQIGAVIVSTVSHFKQTPAVATEIADKLGTGKAAAFDISAGCAGFGYGLTLAKGMIVEGSAKYVLVIGVERLSDLTDLQDRATAFLFGDGAGAVVVGPSDEPAIGPTIWGSEGDKSETIKQTVPWTEYDSSGKFPAITQEGQAVFRWAVFEMAKVAQQALDAAGISPDDLDVFIPHQANMRIIDSMVKTLKLPDHVTVARDVETTGNTSAASIPLAMERLLATGQAKSGDTALVIGFGAGLVYAATVVTLP
>CP032698.1|AYG83115.1|5948121_5949039_-|Malonyl-CoA-acyl-carrier-protein-transacylase
MLVLVAPGQGAQTPGFLTPWLDLPGAADRLAAWSDAIGLDLVHYGTQADADAIRDTAVAQPLLVAAGLLSASALGDFAPGAVAGHSVGEITATAFAGVLSEEAALGFVRKRGLGMAEAAAVTPTGMAALLGGAPADVLPHLEKLGLTPANVNGAGQIVAAGTAEQLAALEADKPEGVRRVVALKVAGAFHTHHMNPAVAALDEAAKSLAIADPKLTYVSNADGKTVASGQDIVARLVNQVSNPVRWDLCMETFTELGATALVELCPGGTLTGLAKRAMPGVKTVALKTPADLDAARALIAEHASA
>CP032698.1|AYG83116.1|5949130_5950327_-|Proline-responsive-transcriptional-activator-PutR
MPAPDPVHPAKNAHPHAATLKRLEQSSGRLAANAIARMDATLPWYRAMPPENRSWIGLVAQAGIAAFTEWFRHPETPQAISTDVFGTAPRELTRAITLRQTVEMVRTTIEVMETAIEEVAAPGDESILREALLVYAREIAFATAQVYAQAAEARGAWDARLESLVVNAVLSGEADEGAVSRAAALGWNSPEHVCVVLGTAPDGDSELTVEAIRRAARHTKLQVLTGVLGNRLVVIAGGSDNPLQVAKGLIGPYAAGPVVAGPVVPDLLAATRSAQAAAAGLKACSAWQDAPRPVLADDLLPERAIASDPAARGQLVEEIYRPLEEAGSALLETLSVYLEQASSLEGAARMLFVHPNTVRYRLRRVTDVTGWSPSDVRSAFTLRIALILGRLADGDSQS
>CP032698.1|AYG83117.1|5950418_5951087_+|Putative-quercetin-2,3-dioxygenase
MVGVISVRRGDERYPGGDPDVGIESLHAFSFGRFYDPDNLRFGPVLACNEERLAPGAGFDEHPHSHTEILTWVIEGELTHRDSAGHATVVRPGDVQCLSSAGGVRHEERNEGQLPLVFLQMWLAPKKPGGTPAYDIVRGIADSTPYAVLAAGALLHVRRLAPGERTAVPDAPGAYVHVVRGRVGLAEERLGPGDSARITGASGLEVTASDSAELLLWELSAV
>CP032698.1|AYG83118.1|5951126_5951945_-|D-alanyl-D-alanine--carboxypeptidase/endopeptidase-AmpH
MESLRIIETWPVPTAAAAVVRADGTLAGTYGPLSQRFPLASVTKPLAAYAALVAYEEGAVELDEPAGPPGATVRHLLAHTSGLAFDEQRAMAQPGDRRLYSNAGFEVLGDHIAKQSGIPFADYVRQAVFEPLGMASSILEGSPAKDGVSTVEDLARFAAELQAPRLIHPATAAEATHVQYPGLKGVLPAYGHQNPNDWGLGFEIRGAKSPHWTGSSSSPRTYGHFGQSGTFLWVDPDAGLACVVLTDRAFGSWAAEVWPSFTDAVLAEFTRR
>CP032698.1|AYG83119.1|5952114_5952576_+|putative-HTH-type-transcriptional-regulator
MIDSTTVTVARVQQEICATEPAHPRPDGQDRYTISEVVTCTGLTAHTLRWYERIGLMPHVDRSHTGQRRFTNKDLDWLAFVGKLRLTGMPVADMVRYAELVREGQHTFEARQELLEQTRRDVLARMAELQDTLAVLDYKIDFYADARKASERA

Crispr_ID: CP032698_80

• CRISPR_ID: CP032698_80
• CRISPR_location: 6011939-6012038
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_80

Consensus_repeat	Method
GGGGTCTGGGGCGCAGCCCCAGGG	CRISPRCasFinder

spacers of CP032698_80

>80.1|6011963|52|CP032698|CRISPRCasFinder
GGCCCGGGCCAGCCAACCCCCGTCACGGGTGGGTGGTGGGCAAAAGGGGCCC

CRISPR arrays and Neighbor proteins around CP032698_80

CRISPR arrays

The CRISPR arrays of CP032698_80

>merge|CP032698|80|6011939-6012038|CRISPRCasFinder
GGGGTCTGGGGCGGAGCCCCAGGGGGCCCGGGCCAGCCAACCCCCGTCACGGGTGGGTGGTGGGCAAAAGGGGCCCGGGGTCCGGGGCGAATCCCCGGGG

>CP032698|80|58|6011939-6012038|CRISPRCasFinder
GGGGTCTGGGGCGGAGCCCCAGGG	GGCCCGGGCCAGCCAACCCCCGTCACGGGTGGGTGGTGGGCAAAAGGGGCCC
GGGGTCCGGGGCGAATCCCCGGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD	unknown	unknown	gnl|CDD|213192
CP032698.1|AYG83173.1|6001526_6002201_-|Sugar-phosphatase-YfbT	unknown	unknown	gnl|CDD|319829
CP032698.1|AYG83172.1|6000745_6001327_+|hypothetical-protein	unknown	unknown	gnl|CDD|225030
CP032698.1|AYG83177.1|6006229_6006559_-|Heme-degrading-monooxygenase-HmoB	unknown	unknown	gnl|CDD|225209
CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR	unknown	unknown	gnl|CDD|380056
CP032698.1|AYG83176.1|6005601_6006093_-|hypothetical-protein	unknown	unknown	gnl|CDD|366181
CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase	unknown	unknown	gnl|CDD|225035
CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein	unknown	unknown	gnl|CDD|378988
CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase	unknown	unknown	gnl|CDD|181145
CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein	unknown	unknown	gnl|CDD|224064
CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein	unknown	unknown	gnl|CDD|223692
CP032698.1|AYG83174.1|6002439_6003357_-|Spore-cortex-lytic-enzyme	unknown	unknown	gnl|CDD|366659
CP032698.1|AYG83186.1|6016537_6017179_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83175.1|6003549_6005592_+|Multidrug-resistance-protein-3	unknown	unknown	gnl|CDD|129794
CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase	unknown	unknown	gnl|CDD|293811
CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein	unknown	unknown	gnl|CDD|366654
CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein	unknown	unknown	gnl|CDD|238362
CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein	unknown	unknown	gnl|CDD|378961
CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase	unknown	unknown	gnl|CDD|143457
CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein	unknown	unknown	gnl|CDD|370813

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD	gnl|CDD|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	5.4498e-79
CP032698.1|AYG83173.1|6001526_6002201_-|Sugar-phosphatase-YfbT	gnl|CDD|319829	cd07527, HAD_ScGPP-like, subfamily of beta-phosphoglucomutase-like family, similar to Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). This subfamily includes Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). GPP1p and GPP2p are involved in glycerol biosynthesis, GPP1 is induced in response to both anaerobic and hyperosmotic stress, GPP2 is induced in response to hyperosmotic or oxidative stress, and during diauxic shift; overexpression of DOG1 or DOG2 confers 2-deoxyglucose resistance. These belong to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), and Escherichia coli 6-phosphogluconate phosphatase YieH. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	3.07929e-69
CP032698.1|AYG83172.1|6000745_6001327_+|hypothetical-protein	gnl|CDD|225030	COG2119, COG2119, Predicted membrane protein [Function unknown].	1.01422e-25
CP032698.1|AYG83177.1|6006229_6006559_-|Heme-degrading-monooxygenase-HmoB	gnl|CDD|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	7.3177e-21
CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR	gnl|CDD|380056	pfam17925, TetR_C_20, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present the transcriptional regulator KstR that regulates a large set of genes responsible for cholesterol catabolism. This is important for Mycobacterium tuberculosis during infection, both at an early stage in the macrophage phagosome and later within the necrotic granuloma.	1.91136e-36
CP032698.1|AYG83176.1|6005601_6006093_-|hypothetical-protein	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.99032e-12
CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.02866e-95
CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein	gnl|CDD|378988	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase. Pyridoxamine 5'-phosphate oxidase is a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). This entry contains several pyridoxamine 5'-phosphate oxidases, and related proteins.	5.6221e-39
CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase	gnl|CDD|181145	PRK07850, PRK07850, steroid 3-ketoacyl-CoA thiolase.	0
CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein	gnl|CDD|224064	COG1141, Fer, Ferredoxin [Energy production and conversion].	4.22638e-08
CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein	gnl|CDD|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	2.92569e-10
CP032698.1|AYG83174.1|6002439_6003357_-|Spore-cortex-lytic-enzyme	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	8.95772e-16
CP032698.1|AYG83175.1|6003549_6005592_+|Multidrug-resistance-protein-3	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.68255e-77
CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase	gnl|CDD|293811	cd07725, TTHA1429-like_MBL-fold, uncharacterized Thermus thermophilus TTHA1429 and related proteins; MBL-fold metallo hydrolase domain. Includes the MBL-fold metallo hydrolase domain of uncharacterized Thermus thermophilus TTHA1429 and related proteins. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	7.98134e-37
CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein	gnl|CDD|366654	pfam01464, SLT, Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.	7.14623e-05
CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein	gnl|CDD|238362	cd00688, ISOPREN_C2_like, This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate complement. Class II terpene cyclases include squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY), these integral membrane proteins catalyze a cationic cyclization cascade converting linear triterpenes to fused ring compounds. The protein prenyltransferases include protein farnesyltransferase (FTase) and geranylgeranyltransferase types I and II (GGTase-I and GGTase-II) which catalyze the carboxyl-terminal lipidation of Ras, Rab, and several other cellular signal transduction proteins, facilitating membrane associations and specific protein-protein interactions. Alpha (2)-M is a major carrier protein in serum and involved in the immobilization and entrapment of proteases. PZP is a pregnancy associated protein. Alpha (2)-M and PZP are known to bind to and, may modulate, the activity of placental protein-14 in T-cell growth and cytokine production thereby protecting the allogeneic fetus from attack by the maternal immune system.	8.98769e-09
CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein	gnl|CDD|378961	pfam12822, ECF_trnsprt, ECF transporter, substrate-specific component. Energy-coupling factor (ECF) transporters consist of a substrate-specific component (known as the S component), and an energy-coupling module. The substrate-binding component is a small integral membrane protein which captures specific substrates and forms an active transporter in the presence of the energy-coupling AT module.	7.57278e-15
CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase	gnl|CDD|143457	cd07139, ALDH_AldA-Rv0768, Mycobacterium tuberculosis aldehyde dehydrogenase AldA-like. The Mycobacterium tuberculosis NAD+-dependent, aldehyde dehydrogenase PDB structure, 3B4W, and the Mycobacterium tuberculosis H37Rv aldehyde dehydrogenase AldA (locus Rv0768) sequence, as well as the Rhodococcus rhodochrous ALDH involved in haloalkane catabolism, and other similar sequences, are included in this CD.	0
CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein	gnl|CDD|370813	pfam10092, DUF2330, Uncharacterized protein conserved in bacteria (DUF2330). Members of this family of hypothetical bacterial proteins have no known function.	3.42283e-84

Protein sequences

>CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase
MAAEPVIVEAVRTPIGKRGGALANLHPAYLLGETYRELLGRTGIHADCVEQIVGGTVTHAGEQSMNPARNAWLAVGLPYETAATTVDCQCGSSQQASHMVANMIAAGVIDVGISCGVEAMSRVPLGSGSKHGPGKPWPDEWNVDLPNQFEAAERIARNRGLTRERVDALGLMSQERAAVAWAEERFKRETFAVQVPTTEEEQAAGQGMWRLVDRDEGLRDTSMEALGRLKPVMPTAVHTAGNSSQISDGSAAIMWASKRMARALKLKPRARIVAQALVGADPHFHLDGPIDATRAVLGKAGMSLRDIDLVEINEAFASVVLSWAQVFEQDLEKVNVNGGAIALGHPVGATGARLIATALHELERRGKEFALVTMCAGGALATATILQRL
>CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase
MRCPHLPDGFDFTDPDLLQSRVPHPEFAELRQTAPVWWCAQPTGISGFQDDGYWAVTRHADVKYVSTHPELFSSHTNTAVIRFNESISREQIDVQKLIMLNMDPPEHTRVRQIVQRGFTPRAIRSLEGALRDRARGIVDAALSEADKNDGAFDFVTQIAVELPLQAIAELIGVPQEDRTKIFDWSNKMAAYDDPEYAITEEIGAEAAMELVSYAMNLAAARKECPAKDIVSQLVAAEGEGNLLSDEFGFFVILLAVAGNETTRNAISHGMHAFLTHPDQWELYKRERPVTAAEEIVRWATPVVAFQRTATQDTELGGQKIKAGDRVGIFYSSANNDPEVFEEPDRFDITRDPNPHLGFGGGGPHFCLGKSLAVLEINLIFNAIADVLPDLRLAGDPRRLRSAWLNGIKGLRVIHG
>CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein
MDVQQPDQHARPEPAAPVGLAVTERTRHRRLREQGSTRVEDLDAILKAGFVCHLGVVVDGTPMVVPTVYGVDFATRTLFLHGSVASRSIVAAPRATVCVTVTHIDGLVLARSVFEHGVNYRSAMVYAVPRLITEGDELLHGLRVLTEHCAPGQWDYARRPNSRELAATSLLALSLEEASVKTASGPPEDGQGPDGELGLWAGVVPLHSHFGPPEPDPALAAGIAMPGHVALLGTGRDTRP
>CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein
MRDGTGRLRRTGDGRRPWRRVLLVALALVALQLGSLVAPAYACGCGAMVPQSGRQLSVRQETSAVRWDGHHEQIVMRLTVDGNAPQAAWIMPVPSRATVKLGDRQLFDELERLSAPVHRTRTYFWPRSGDWPLARDRSVGDGAPRPAAKPPVEVVGRERLGPFDVARLTASDPTALRDWLSRNGFQLPPALSTELRPYVDQKWEYVAIRLAPDRPGRALGGPLDPLSLSFASDRLIYPMRLSRLAKTPQTLDLYVLADHRMETASTIGGDRPETLFAGDVEHPSGPLAELTGGTGPVYLTALTQFFTRPSRITGDHELTRAADDTGFQRTWYTDELMTVGGAPLWLVTVGGALAVLLAGALGTVLAVRGRRRRRGDAQLPEPVSHSRPA
>CP032698.1|AYG83177.1|6006229_6006559_-|Heme-degrading-monooxygenase-HmoB
MPSVVKINVLTVPDEQREVLEKRFASRAGSVEGSDGFEWFELLRPVEGTDQYLVYTRWRSEEDFQNWMATSMRGSHGGAQGEGGERPKPAASGSTLWSFEVVQQAAPTE
>CP032698.1|AYG83176.1|6005601_6006093_-|hypothetical-protein
MAVERPDTPDASLLRRDYYDEVASRWYGRAATDEEIEQGLTDDGADRLWPPTGDFVVGRFQGRPAACGGVLLCAKAPVIDGTAPATAELTRVFVRPFARGTGGGGALLSALEDAARRLGARRIALDTRHDLVEARGLYAKHGYREIDPYNQGPYSERWFAKEL
>CP032698.1|AYG83175.1|6003549_6005592_+|Multidrug-resistance-protein-3
MAQRTAPAAVAPGAGHERRNVLVAIGALLLGMLIAALDQTIVSTALPTIVSDLGGMEHLSWVVTAYMLAATAATPLWGKLGDQYGRKKLFQLAILIFLIGSGLCGIAQNMGELIGFRALQGLGGGGLMVLSMAIVGDIVSPRERGKYQGLFGAVFGATSVLGPLLGGFFTEQLSWRWVFYINLPIGVIALLVIAAVLHIPARGTRHTIDYLGTFLIASVATCLVLVASLGGTTWPWASARIIGLAVLGVLLLVVFVAVERRAAEPVLPLKLFRVRTFTLVAVISFIVGFAMFGAMTYLPTFLQIVRGISPTMSGVHMLPMVLGMLLTSTASGQIVSRTGRWKVFPIAGTALTTIGLLLLHRLTETSSTWEMSLYFFVFGAGLGLVMQVLVLVVQNAVDYADLGVATSGATFFRSIGASFGVAIFGTIFTNRLTGKLSDALAGQPLPPGTGPATIAADPHTIAQLPPAARPSVLHAYASSITDVFLYAAPVVLLAFVTAWFLREDKLRGAVTAPDTSQTLASNPVERSSYDECARALSVLGTREGRREIYRTITKKADLDLLPAASWLLLRINKYGSAEPAMLAERSPVPIQVITEAARQVEERGLARREGLPLVLTEPGREVAVRLVAAREESLAELLGDWWGPNRPRDLVKLIAELSSELSGSDGEQPTGPAPHHGGRA
>CP032698.1|AYG83174.1|6002439_6003357_-|Spore-cortex-lytic-enzyme
MTGHGCPECGAERGVDGRPGCVCAERAAQTLHAERSAQAAATEEFDPLRIRPYVMLPNASAAPDEGPSGVVGVPDAERTMRLGAVVAAARPDPVRAPRPTVPDGAGAPRRRRRLVALTAGAAAAVVIATAAFASTLFADDATPKRALPDAADTGLPYSGGDTAPAGTPSASASPSKKATPSRSPSARPSPTPSASASRAASPTPSKHTPTPSPSAPGPSASTGGKPVAPPPSTTLRRGDSGPGVLELQERLAQLGLYSGHADGTFGSRTERAVRDFQSYTGVSGDPAGVYGPPTRQALESMTDQP
>CP032698.1|AYG83173.1|6001526_6002201_-|Sugar-phosphatase-YfbT
MPASATTTTVLTARALLLDMDGTIVNSDAVVERCWRGWAERHGLDPEAALKVVHGRQGYATMALLLPDRPMEQNHADNKVMLAEETADTDGVVPVPGAPAFMASLAGLPHALVTSADAALARARMTAAGLPMPDVRVTAECVGASKPDPEGFLKGAAELGFDPAQCVVFEDSEAGIAAGRAAGMRVVGVGPRANAHEPTAYVPDLTHVTVTAEADGTLRLEIAG
>CP032698.1|AYG83172.1|6000745_6001327_+|hypothetical-protein
MLSFTIMAITFGVIFLAELPDKTALAGLMLGTRYKASYVFVGVAAAFAVHVVLAIAAGSVLTLLPHRLLQAIVGVLFLAGAAMLLFKKDEDDEEVKAPSDQSFWKVSGAGFMLILVAEFGDLTQIMTANLAARYDNPLSVGIGAVLALWAVAGLGIVGGRALMKRVPLRLITKVAACLMLALAGFSLFEAITG
>CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein
MPPRLGFALSFAARFTARKKSVAAAGATLLAASGVALAAVPAQAAPTSAQAIARQMMPSDQFQCFSKIVNHESGWNPSATNASSGAYGLVQALPGSKMASAGADWQTNPATQIKWGLGYMNERYGSPCGAWSFWQQNNWY
>CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein
MTHTTEPPEPTGPAKRTRPDHAGRAVPAVRLGPRAVVALSLITLIGIAVFGWPLLADANSGLAHARDAPWLFAALLPLLVGVVIATIADDGMDAKAVAMLGVLAAVGAALRPLGAGTAGLEPMFFLMVLSGRVLGPGFGFVLGSVTMFASALLTGGVGPWMPFQMLAMGWFTMGAGLLPGPHRLRGRAECALLALYGALASFAYGTVMNLQGWTFIGGLSSGISFHPGDPLHDNLIRFFAYCAATSLGWDLGRAALTVVLTLTLGTTLLKALRRATRRAAFEAQVTFED
>CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD
MIRFENVSVTYDGADEATVRDVELAIPEGELVLLVGPSGVGKSTLLGTVSGLVPHFTGGTLRGRVTVDGRDTRTHKPRELADLVGTVGQDPLAHFVTDTVEDELAYGMESLGLAPAVMRRRVEETLDLLGLAELRDRPIATLSGGQQQRVAIGSVLTPHPKVLVLDEPTSALDPAAAEDVLSVLQRLVHDLGTTVLLAEHRLERVVQYADQVVLLPSPGAPPMMGTPADIMKVSPVHPPVVALGHLAGWTPLPLSVRDARRRSGPLRTELSTRVAAEPRTEARPAEPRPRAAAPRTLTRFFRRPQTPPAPTGTATATALGVRRGRVEALRRVDLTVAPGEIIALMGRNGAGKSTLLNTLVGMVEPTTGSVTVGGRTPHRTPPAELIREVGLVPQEPRDLLYANTVAAECAAADADAGAAPGSCRSLVSALLPGVRDDTHPRDLSEGQRLALALAIVLTGRPPLLLLDEPTRGLDYAAKARLVEVLRALAAEGHAIVLATHDVELAAELAHRVVILAGGEVVADGPTAEVVVSSPAFAPQIAKVLAPQHWLTVSQVREALS
>CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein
MHPGAWWLWALGLATAASRTNNPLLLGLLVGVAGYVVAARKTDAPWARSYTAFIKIGLFVVGIRLAFNVVLGSPIPGSHTLFTLPQLPLPDWAKGIRVGGRVTAEGMLFALYDGARLATLLICVGAANALANPARLLKSLPGALYEAGVAVVVAMTFAPNMVADVVRLRTARRLRGRPTGGLRAIAQIGLPVLEGALERSVAVAASMDARGYGRTAQVPAPVRLTTTVLTLGGLLGVCAGTYGLLASEGAGYGLPVLAGGVLASLAGLRLGGRRQLRTRYRPDRWGVRSWLVAGSGVAVAGLLLWTGTYAPEALTLGVVPLAAPSLPLWPALSLLAGLLPAFVAPVPPKESP
>CP032698.1|AYG83186.1|6016537_6017179_-|hypothetical-protein
MRTRLAAFAAPLLALVVLATGAGPAQAAGYRYWAFWDLAGDAWTYATQGPASAHPGDGSVQGFRFAVSADSRDASQPRTAPSFEAVCGTTPTKDGTKRVALVIDFGTPEDATPGETPPAARNACAQVPPDATTADALAAVAKPLRYNSAALLCAIGGYPRTGCGEQVADPSAPKAEPANTGHDSGPSVGLLAGVAAVLALGAAAIWQARRRRN
>CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein
MTVRRSAAALTAALAAATAVLGGAAPAAFADGTPSPAALPPGLYGTKDPQFDGVFRQSLAFLAQEKTNVKPAEQAIAWLAGQQCADGSFTSFRADTATACDPKKLDTNATAAAVQAFVAVGGHADAIKKGVSWLKSVQQDDGGWPYTPGMGGSDSNSTAIVVGALAAAGEKPADVKSAKGGKTPFDALLTFALPCDDPAGPGAFAFQPDPKTQKLYANADATAAAVTGALGKGLTAGAGPADAKGTACERATTPEQAAHNGSAYLAKTLAPTGFLKSAMPGATDQPDFGNTADAVVALAAAGQTQQAKASADWLAKNAGAWAKENGPAAYAQLVFAADATGADPNNFGGLNLVTSLNATGPAPQTAVTSTPSAQTSHSKDDDGISVWWIVGAGLVAGIGVGFLISGRKKNQRL
>CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase
MPQEPAAPQVSDHGGGVHSIKVPIPDNPLGHTLVHLVDTDRGPVLIDTGWDDPASWNTLTAGLRALGTDVSAVHGVVITHHHPDHHGLSGQVREASGAWIAMHAADAAVVRRTREAQPGVWLDYLCAKLTAVGAPDEHIAPLRQARASGRARTLPGLRAALPDREIVPGDLLPLAGRRLRAIWTPGHTPGHVCLHLEEAHPSQLPGHGRLFSGDHLLPGITPHIGLYEDPDDGESTDPLGDYLDSLERVGRLGVAEVLPAHQHAFAEPGVRVRELLAHHEERLAGLLSLLSAPLTPWELAERMEWNRPWGQIPDGSRTIAVSEAEAHVRRLEKLGRVVRVGGSPARYHAV
>CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase
MTELVEHGQLFIGGELTDPLGSDVIEVISPHTEQVIGRVPHACRADVDRAVAAARTAFDTGPWARATPEERIEVVSRIKDAILARHEEIARCISAQNGSPYSWSVLAQALGAMMVWDSAITVARRFPYEERRSGALGPLLVRREPVGVVAAVVPWNVPQFVAAAKLGPALLTGCSVILKPSPETPLDAYILGEIAAEAGLPEGVLSILPADREVSEYLVGHPGVDKVSFTGSVAAGKRVMEVAARNLTRVTLELGGKSAAVILPDADLETTVAGVASAAWMNNGQACVAQTRILAPRARYEEFAEAFAAAAGALVVGDPLDPATQVGPLVAERQRQRSLDYIRIGQEEGAKILSGGGRPAGLERGWYVEPTLFGGVDNTMRIAREEIFGPVICLLPYGDEAEALGIANDSEYGLSGSVWTGDVEHGIDFGRRVRTGTFNVNTFSLDMLGPFGGYKSSGLGREFGPEGFGEYLEHKMIHLPAGHGGE
>CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein
MGDRWHVEVDRSVCIGSGMCVNHAPAAFELDSARQSQPREPDTDAGEQVLAAAEGCPVEAILITLLGSGETVFPPED
>CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR
MTAEAKAAIPATPPLTERQEARRRRILHASAQLASRGGFDAVQMREVAEAAGVALGTLYRYFPSKIHLLVATMQDQLQHLHGTLRKHPPSGAGSAERVAETLMRAFRALQREPHLADAMVRALTFADRSVSPEVDTVSRQTTAIILDAVGLEHPTPEQLSAVRVIEHTWHSALITWLSGRASIAQVKIDIETVCKLIDLTTPPNP

Crispr_ID: CP032698_79

• CRISPR_ID: CP032698_79
• CRISPR_location: 6011544-6011737
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of CP032698_79

Consensus_repeat	Method
GTC----------------GCGCAGTTCCCCGCGCCCCT	PILER-CR

spacers of CP032698_79

>79.1|6011567|33|CP032698|PILER-CR
AAACCCTCCCGAACCTGCGGGCCGTGGTCGCTT
>79.2|6011623|37|CP032698|PILER-CR
AAGAAACCCGTTTTCGTCTGCGGGCCGTACGTGGCTG
>79.3|6011683|32|CP032698|PILER-CR
GGCAGGACTGGTGCCGGCCCGGACGGGACTTG

CRISPR arrays and Neighbor proteins around CP032698_79

CRISPR arrays

The CRISPR arrays of CP032698_79

>merge|CP032698|79|6011544-6011737|PILER-CR
GTTGCGCAGTTCCCCGCGCCCCTAAACCCTCCCGAACCTGCGGGCCGTGGTCGCTTCTCGCGCAGTTCCTCGCGCCCCCAAGAAACCCGTTTTCGTCTGCGGGCCGTACGTGGCTGGTCGCGCAGTTCCCCGCGCCCCTGGCAGGACTGGTGCCGGCCCGGACGGGACTTGGGCGCGCAGTTCCTCGCGCCCCT

>CP032698|79|21|6011544-6011737|PILER-CR
GTTGCGCAGTTCCCCGCGCCCCT	AAACCCTCCCGAACCTGCGGGCCGTGGTCGCTT
CTCGCGCAGTTCCTCGCGCCCCC	AAGAAACCCGTTTTCGTCTGCGGGCCGTACGTGGCTG
GTCGCGCAGTTCCCCGCGCCCCT	GGCAGGACTGGTGCCGGCCCGGACGGGACTTG
GGCGCGCAGTTCCTCGCGCCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD	unknown	unknown	gnl|CDD|213192
CP032698.1|AYG83173.1|6001526_6002201_-|Sugar-phosphatase-YfbT	unknown	unknown	gnl|CDD|319829
CP032698.1|AYG83172.1|6000745_6001327_+|hypothetical-protein	unknown	unknown	gnl|CDD|225030
CP032698.1|AYG83177.1|6006229_6006559_-|Heme-degrading-monooxygenase-HmoB	unknown	unknown	gnl|CDD|225209
CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR	unknown	unknown	gnl|CDD|380056
CP032698.1|AYG83176.1|6005601_6006093_-|hypothetical-protein	unknown	unknown	gnl|CDD|366181
CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase	unknown	unknown	gnl|CDD|225035
CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein	unknown	unknown	gnl|CDD|378988
CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase	unknown	unknown	gnl|CDD|181145
CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein	unknown	unknown	gnl|CDD|224064
CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein	unknown	unknown	gnl|CDD|223692
CP032698.1|AYG83174.1|6002439_6003357_-|Spore-cortex-lytic-enzyme	unknown	unknown	gnl|CDD|366659
CP032698.1|AYG83186.1|6016537_6017179_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83175.1|6003549_6005592_+|Multidrug-resistance-protein-3	unknown	unknown	gnl|CDD|129794
CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase	unknown	unknown	gnl|CDD|293811
CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein	unknown	unknown	gnl|CDD|366654
CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein	unknown	unknown	gnl|CDD|238362
CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein	unknown	unknown	gnl|CDD|378961
CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase	unknown	unknown	gnl|CDD|143457
CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein	unknown	unknown	gnl|CDD|370813

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD	gnl|CDD|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	5.4498e-79
CP032698.1|AYG83173.1|6001526_6002201_-|Sugar-phosphatase-YfbT	gnl|CDD|319829	cd07527, HAD_ScGPP-like, subfamily of beta-phosphoglucomutase-like family, similar to Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). This subfamily includes Saccharomyces cerevisiae DL-glycerol-3-phosphate phosphatase (GPP1p/ Rhr2p and GPP2p/HOR2p) and 2-deoxyglucose-6-phosphate phosphatase (DOG1p and DOG2p). GPP1p and GPP2p are involved in glycerol biosynthesis, GPP1 is induced in response to both anaerobic and hyperosmotic stress, GPP2 is induced in response to hyperosmotic or oxidative stress, and during diauxic shift; overexpression of DOG1 or DOG2 confers 2-deoxyglucose resistance. These belong to the beta-phosphoglucomutase-like family whose other members include Lactococcus lactis beta-PGM, a mutase which catalyzes the interconversion of beta-D-glucose 1-phosphate (G1P) and D-glucose 6-phosphate (G6P), and Escherichia coli 6-phosphogluconate phosphatase YieH. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	3.07929e-69
CP032698.1|AYG83172.1|6000745_6001327_+|hypothetical-protein	gnl|CDD|225030	COG2119, COG2119, Predicted membrane protein [Function unknown].	1.01422e-25
CP032698.1|AYG83177.1|6006229_6006559_-|Heme-degrading-monooxygenase-HmoB	gnl|CDD|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	7.3177e-21
CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR	gnl|CDD|380056	pfam17925, TetR_C_20, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present the transcriptional regulator KstR that regulates a large set of genes responsible for cholesterol catabolism. This is important for Mycobacterium tuberculosis during infection, both at an early stage in the macrophage phagosome and later within the necrotic granuloma.	1.91136e-36
CP032698.1|AYG83176.1|6005601_6006093_-|hypothetical-protein	gnl|CDD|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.99032e-12
CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.02866e-95
CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein	gnl|CDD|378988	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase. Pyridoxamine 5'-phosphate oxidase is a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). This entry contains several pyridoxamine 5'-phosphate oxidases, and related proteins.	5.6221e-39
CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase	gnl|CDD|181145	PRK07850, PRK07850, steroid 3-ketoacyl-CoA thiolase.	0
CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein	gnl|CDD|224064	COG1141, Fer, Ferredoxin [Energy production and conversion].	4.22638e-08
CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein	gnl|CDD|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	2.92569e-10
CP032698.1|AYG83174.1|6002439_6003357_-|Spore-cortex-lytic-enzyme	gnl|CDD|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	8.95772e-16
CP032698.1|AYG83175.1|6003549_6005592_+|Multidrug-resistance-protein-3	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.68255e-77
CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase	gnl|CDD|293811	cd07725, TTHA1429-like_MBL-fold, uncharacterized Thermus thermophilus TTHA1429 and related proteins; MBL-fold metallo hydrolase domain. Includes the MBL-fold metallo hydrolase domain of uncharacterized Thermus thermophilus TTHA1429 and related proteins. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	7.98134e-37
CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein	gnl|CDD|366654	pfam01464, SLT, Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.	7.14623e-05
CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein	gnl|CDD|238362	cd00688, ISOPREN_C2_like, This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate complement. Class II terpene cyclases include squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY), these integral membrane proteins catalyze a cationic cyclization cascade converting linear triterpenes to fused ring compounds. The protein prenyltransferases include protein farnesyltransferase (FTase) and geranylgeranyltransferase types I and II (GGTase-I and GGTase-II) which catalyze the carboxyl-terminal lipidation of Ras, Rab, and several other cellular signal transduction proteins, facilitating membrane associations and specific protein-protein interactions. Alpha (2)-M is a major carrier protein in serum and involved in the immobilization and entrapment of proteases. PZP is a pregnancy associated protein. Alpha (2)-M and PZP are known to bind to and, may modulate, the activity of placental protein-14 in T-cell growth and cytokine production thereby protecting the allogeneic fetus from attack by the maternal immune system.	8.98769e-09
CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein	gnl|CDD|378961	pfam12822, ECF_trnsprt, ECF transporter, substrate-specific component. Energy-coupling factor (ECF) transporters consist of a substrate-specific component (known as the S component), and an energy-coupling module. The substrate-binding component is a small integral membrane protein which captures specific substrates and forms an active transporter in the presence of the energy-coupling AT module.	7.57278e-15
CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase	gnl|CDD|143457	cd07139, ALDH_AldA-Rv0768, Mycobacterium tuberculosis aldehyde dehydrogenase AldA-like. The Mycobacterium tuberculosis NAD+-dependent, aldehyde dehydrogenase PDB structure, 3B4W, and the Mycobacterium tuberculosis H37Rv aldehyde dehydrogenase AldA (locus Rv0768) sequence, as well as the Rhodococcus rhodochrous ALDH involved in haloalkane catabolism, and other similar sequences, are included in this CD.	0
CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein	gnl|CDD|370813	pfam10092, DUF2330, Uncharacterized protein conserved in bacteria (DUF2330). Members of this family of hypothetical bacterial proteins have no known function.	3.42283e-84

Protein sequences

>CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase
MAAEPVIVEAVRTPIGKRGGALANLHPAYLLGETYRELLGRTGIHADCVEQIVGGTVTHAGEQSMNPARNAWLAVGLPYETAATTVDCQCGSSQQASHMVANMIAAGVIDVGISCGVEAMSRVPLGSGSKHGPGKPWPDEWNVDLPNQFEAAERIARNRGLTRERVDALGLMSQERAAVAWAEERFKRETFAVQVPTTEEEQAAGQGMWRLVDRDEGLRDTSMEALGRLKPVMPTAVHTAGNSSQISDGSAAIMWASKRMARALKLKPRARIVAQALVGADPHFHLDGPIDATRAVLGKAGMSLRDIDLVEINEAFASVVLSWAQVFEQDLEKVNVNGGAIALGHPVGATGARLIATALHELERRGKEFALVTMCAGGALATATILQRL
>CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase
MRCPHLPDGFDFTDPDLLQSRVPHPEFAELRQTAPVWWCAQPTGISGFQDDGYWAVTRHADVKYVSTHPELFSSHTNTAVIRFNESISREQIDVQKLIMLNMDPPEHTRVRQIVQRGFTPRAIRSLEGALRDRARGIVDAALSEADKNDGAFDFVTQIAVELPLQAIAELIGVPQEDRTKIFDWSNKMAAYDDPEYAITEEIGAEAAMELVSYAMNLAAARKECPAKDIVSQLVAAEGEGNLLSDEFGFFVILLAVAGNETTRNAISHGMHAFLTHPDQWELYKRERPVTAAEEIVRWATPVVAFQRTATQDTELGGQKIKAGDRVGIFYSSANNDPEVFEEPDRFDITRDPNPHLGFGGGGPHFCLGKSLAVLEINLIFNAIADVLPDLRLAGDPRRLRSAWLNGIKGLRVIHG
>CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein
MDVQQPDQHARPEPAAPVGLAVTERTRHRRLREQGSTRVEDLDAILKAGFVCHLGVVVDGTPMVVPTVYGVDFATRTLFLHGSVASRSIVAAPRATVCVTVTHIDGLVLARSVFEHGVNYRSAMVYAVPRLITEGDELLHGLRVLTEHCAPGQWDYARRPNSRELAATSLLALSLEEASVKTASGPPEDGQGPDGELGLWAGVVPLHSHFGPPEPDPALAAGIAMPGHVALLGTGRDTRP
>CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein
MRDGTGRLRRTGDGRRPWRRVLLVALALVALQLGSLVAPAYACGCGAMVPQSGRQLSVRQETSAVRWDGHHEQIVMRLTVDGNAPQAAWIMPVPSRATVKLGDRQLFDELERLSAPVHRTRTYFWPRSGDWPLARDRSVGDGAPRPAAKPPVEVVGRERLGPFDVARLTASDPTALRDWLSRNGFQLPPALSTELRPYVDQKWEYVAIRLAPDRPGRALGGPLDPLSLSFASDRLIYPMRLSRLAKTPQTLDLYVLADHRMETASTIGGDRPETLFAGDVEHPSGPLAELTGGTGPVYLTALTQFFTRPSRITGDHELTRAADDTGFQRTWYTDELMTVGGAPLWLVTVGGALAVLLAGALGTVLAVRGRRRRRGDAQLPEPVSHSRPA
>CP032698.1|AYG83177.1|6006229_6006559_-|Heme-degrading-monooxygenase-HmoB
MPSVVKINVLTVPDEQREVLEKRFASRAGSVEGSDGFEWFELLRPVEGTDQYLVYTRWRSEEDFQNWMATSMRGSHGGAQGEGGERPKPAASGSTLWSFEVVQQAAPTE
>CP032698.1|AYG83176.1|6005601_6006093_-|hypothetical-protein
MAVERPDTPDASLLRRDYYDEVASRWYGRAATDEEIEQGLTDDGADRLWPPTGDFVVGRFQGRPAACGGVLLCAKAPVIDGTAPATAELTRVFVRPFARGTGGGGALLSALEDAARRLGARRIALDTRHDLVEARGLYAKHGYREIDPYNQGPYSERWFAKEL
>CP032698.1|AYG83175.1|6003549_6005592_+|Multidrug-resistance-protein-3
MAQRTAPAAVAPGAGHERRNVLVAIGALLLGMLIAALDQTIVSTALPTIVSDLGGMEHLSWVVTAYMLAATAATPLWGKLGDQYGRKKLFQLAILIFLIGSGLCGIAQNMGELIGFRALQGLGGGGLMVLSMAIVGDIVSPRERGKYQGLFGAVFGATSVLGPLLGGFFTEQLSWRWVFYINLPIGVIALLVIAAVLHIPARGTRHTIDYLGTFLIASVATCLVLVASLGGTTWPWASARIIGLAVLGVLLLVVFVAVERRAAEPVLPLKLFRVRTFTLVAVISFIVGFAMFGAMTYLPTFLQIVRGISPTMSGVHMLPMVLGMLLTSTASGQIVSRTGRWKVFPIAGTALTTIGLLLLHRLTETSSTWEMSLYFFVFGAGLGLVMQVLVLVVQNAVDYADLGVATSGATFFRSIGASFGVAIFGTIFTNRLTGKLSDALAGQPLPPGTGPATIAADPHTIAQLPPAARPSVLHAYASSITDVFLYAAPVVLLAFVTAWFLREDKLRGAVTAPDTSQTLASNPVERSSYDECARALSVLGTREGRREIYRTITKKADLDLLPAASWLLLRINKYGSAEPAMLAERSPVPIQVITEAARQVEERGLARREGLPLVLTEPGREVAVRLVAAREESLAELLGDWWGPNRPRDLVKLIAELSSELSGSDGEQPTGPAPHHGGRA
>CP032698.1|AYG83174.1|6002439_6003357_-|Spore-cortex-lytic-enzyme
MTGHGCPECGAERGVDGRPGCVCAERAAQTLHAERSAQAAATEEFDPLRIRPYVMLPNASAAPDEGPSGVVGVPDAERTMRLGAVVAAARPDPVRAPRPTVPDGAGAPRRRRRLVALTAGAAAAVVIATAAFASTLFADDATPKRALPDAADTGLPYSGGDTAPAGTPSASASPSKKATPSRSPSARPSPTPSASASRAASPTPSKHTPTPSPSAPGPSASTGGKPVAPPPSTTLRRGDSGPGVLELQERLAQLGLYSGHADGTFGSRTERAVRDFQSYTGVSGDPAGVYGPPTRQALESMTDQP
>CP032698.1|AYG83173.1|6001526_6002201_-|Sugar-phosphatase-YfbT
MPASATTTTVLTARALLLDMDGTIVNSDAVVERCWRGWAERHGLDPEAALKVVHGRQGYATMALLLPDRPMEQNHADNKVMLAEETADTDGVVPVPGAPAFMASLAGLPHALVTSADAALARARMTAAGLPMPDVRVTAECVGASKPDPEGFLKGAAELGFDPAQCVVFEDSEAGIAAGRAAGMRVVGVGPRANAHEPTAYVPDLTHVTVTAEADGTLRLEIAG
>CP032698.1|AYG83172.1|6000745_6001327_+|hypothetical-protein
MLSFTIMAITFGVIFLAELPDKTALAGLMLGTRYKASYVFVGVAAAFAVHVVLAIAAGSVLTLLPHRLLQAIVGVLFLAGAAMLLFKKDEDDEEVKAPSDQSFWKVSGAGFMLILVAEFGDLTQIMTANLAARYDNPLSVGIGAVLALWAVAGLGIVGGRALMKRVPLRLITKVAACLMLALAGFSLFEAITG
>CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein
MPPRLGFALSFAARFTARKKSVAAAGATLLAASGVALAAVPAQAAPTSAQAIARQMMPSDQFQCFSKIVNHESGWNPSATNASSGAYGLVQALPGSKMASAGADWQTNPATQIKWGLGYMNERYGSPCGAWSFWQQNNWY
>CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein
MTHTTEPPEPTGPAKRTRPDHAGRAVPAVRLGPRAVVALSLITLIGIAVFGWPLLADANSGLAHARDAPWLFAALLPLLVGVVIATIADDGMDAKAVAMLGVLAAVGAALRPLGAGTAGLEPMFFLMVLSGRVLGPGFGFVLGSVTMFASALLTGGVGPWMPFQMLAMGWFTMGAGLLPGPHRLRGRAECALLALYGALASFAYGTVMNLQGWTFIGGLSSGISFHPGDPLHDNLIRFFAYCAATSLGWDLGRAALTVVLTLTLGTTLLKALRRATRRAAFEAQVTFED
>CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD
MIRFENVSVTYDGADEATVRDVELAIPEGELVLLVGPSGVGKSTLLGTVSGLVPHFTGGTLRGRVTVDGRDTRTHKPRELADLVGTVGQDPLAHFVTDTVEDELAYGMESLGLAPAVMRRRVEETLDLLGLAELRDRPIATLSGGQQQRVAIGSVLTPHPKVLVLDEPTSALDPAAAEDVLSVLQRLVHDLGTTVLLAEHRLERVVQYADQVVLLPSPGAPPMMGTPADIMKVSPVHPPVVALGHLAGWTPLPLSVRDARRRSGPLRTELSTRVAAEPRTEARPAEPRPRAAAPRTLTRFFRRPQTPPAPTGTATATALGVRRGRVEALRRVDLTVAPGEIIALMGRNGAGKSTLLNTLVGMVEPTTGSVTVGGRTPHRTPPAELIREVGLVPQEPRDLLYANTVAAECAAADADAGAAPGSCRSLVSALLPGVRDDTHPRDLSEGQRLALALAIVLTGRPPLLLLDEPTRGLDYAAKARLVEVLRALAAEGHAIVLATHDVELAAELAHRVVILAGGEVVADGPTAEVVVSSPAFAPQIAKVLAPQHWLTVSQVREALS
>CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein
MHPGAWWLWALGLATAASRTNNPLLLGLLVGVAGYVVAARKTDAPWARSYTAFIKIGLFVVGIRLAFNVVLGSPIPGSHTLFTLPQLPLPDWAKGIRVGGRVTAEGMLFALYDGARLATLLICVGAANALANPARLLKSLPGALYEAGVAVVVAMTFAPNMVADVVRLRTARRLRGRPTGGLRAIAQIGLPVLEGALERSVAVAASMDARGYGRTAQVPAPVRLTTTVLTLGGLLGVCAGTYGLLASEGAGYGLPVLAGGVLASLAGLRLGGRRQLRTRYRPDRWGVRSWLVAGSGVAVAGLLLWTGTYAPEALTLGVVPLAAPSLPLWPALSLLAGLLPAFVAPVPPKESP
>CP032698.1|AYG83186.1|6016537_6017179_-|hypothetical-protein
MRTRLAAFAAPLLALVVLATGAGPAQAAGYRYWAFWDLAGDAWTYATQGPASAHPGDGSVQGFRFAVSADSRDASQPRTAPSFEAVCGTTPTKDGTKRVALVIDFGTPEDATPGETPPAARNACAQVPPDATTADALAAVAKPLRYNSAALLCAIGGYPRTGCGEQVADPSAPKAEPANTGHDSGPSVGLLAGVAAVLALGAAAIWQARRRRN
>CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein
MTVRRSAAALTAALAAATAVLGGAAPAAFADGTPSPAALPPGLYGTKDPQFDGVFRQSLAFLAQEKTNVKPAEQAIAWLAGQQCADGSFTSFRADTATACDPKKLDTNATAAAVQAFVAVGGHADAIKKGVSWLKSVQQDDGGWPYTPGMGGSDSNSTAIVVGALAAAGEKPADVKSAKGGKTPFDALLTFALPCDDPAGPGAFAFQPDPKTQKLYANADATAAAVTGALGKGLTAGAGPADAKGTACERATTPEQAAHNGSAYLAKTLAPTGFLKSAMPGATDQPDFGNTADAVVALAAAGQTQQAKASADWLAKNAGAWAKENGPAAYAQLVFAADATGADPNNFGGLNLVTSLNATGPAPQTAVTSTPSAQTSHSKDDDGISVWWIVGAGLVAGIGVGFLISGRKKNQRL
>CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase
MPQEPAAPQVSDHGGGVHSIKVPIPDNPLGHTLVHLVDTDRGPVLIDTGWDDPASWNTLTAGLRALGTDVSAVHGVVITHHHPDHHGLSGQVREASGAWIAMHAADAAVVRRTREAQPGVWLDYLCAKLTAVGAPDEHIAPLRQARASGRARTLPGLRAALPDREIVPGDLLPLAGRRLRAIWTPGHTPGHVCLHLEEAHPSQLPGHGRLFSGDHLLPGITPHIGLYEDPDDGESTDPLGDYLDSLERVGRLGVAEVLPAHQHAFAEPGVRVRELLAHHEERLAGLLSLLSAPLTPWELAERMEWNRPWGQIPDGSRTIAVSEAEAHVRRLEKLGRVVRVGGSPARYHAV
>CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase
MTELVEHGQLFIGGELTDPLGSDVIEVISPHTEQVIGRVPHACRADVDRAVAAARTAFDTGPWARATPEERIEVVSRIKDAILARHEEIARCISAQNGSPYSWSVLAQALGAMMVWDSAITVARRFPYEERRSGALGPLLVRREPVGVVAAVVPWNVPQFVAAAKLGPALLTGCSVILKPSPETPLDAYILGEIAAEAGLPEGVLSILPADREVSEYLVGHPGVDKVSFTGSVAAGKRVMEVAARNLTRVTLELGGKSAAVILPDADLETTVAGVASAAWMNNGQACVAQTRILAPRARYEEFAEAFAAAAGALVVGDPLDPATQVGPLVAERQRQRSLDYIRIGQEEGAKILSGGGRPAGLERGWYVEPTLFGGVDNTMRIAREEIFGPVICLLPYGDEAEALGIANDSEYGLSGSVWTGDVEHGIDFGRRVRTGTFNVNTFSLDMLGPFGGYKSSGLGREFGPEGFGEYLEHKMIHLPAGHGGE
>CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein
MGDRWHVEVDRSVCIGSGMCVNHAPAAFELDSARQSQPREPDTDAGEQVLAAAEGCPVEAILITLLGSGETVFPPED
>CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR
MTAEAKAAIPATPPLTERQEARRRRILHASAQLASRGGFDAVQMREVAEAAGVALGTLYRYFPSKIHLLVATMQDQLQHLHGTLRKHPPSGAGSAERVAETLMRAFRALQREPHLADAMVRALTFADRSVSPEVDTVSRQTTAIILDAVGLEHPTPEQLSAVRVIEHTWHSALITWLSGRASIAQVKIDIETVCKLIDLTTPPNP

Crispr_ID: CP032698_82

• CRISPR_ID: CP032698_82
• CRISPR_location: 6018939-6019039
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_82

Consensus_repeat	Method
GGGGTCTGGGGCGGAGCCCCAGG	CRISPRCasFinder

spacers of CP032698_82

>82.1|6018962|55|CP032698|CRISPRCasFinder
AGGCCCGGGCCATCCAACCCTGCGCCTACGGGCGGGTGGGTGGGGAAGGTGCCTT

CRISPR arrays and Neighbor proteins around CP032698_82

CRISPR arrays

The CRISPR arrays of CP032698_82

>merge|CP032698|82|6018939-6019039|CRISPRCasFinder
GGGGTCTGGGGCGGAGCCCCAGGAGGCCCGGGCCATCCAACCCTGCGCCTACGGGCGGGTGGGTGGGGAAGGTGCCTTGGGGTCTGGGGCGGAGCCCCAGG

>CP032698|82|59|6018939-6019039|CRISPRCasFinder
GGGGTCTGGGGCGGAGCCCCAGG	AGGCCCGGGCCATCCAACCCTGCGCCTACGGGCGGGTGGGTGGGGAAGGTGCCTT
GGGGTCTGGGGCGGAGCCCCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83192.1|6023304_6024627_+|Glycogen-synthase	unknown	unknown	gnl|CDD|340831
CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD	unknown	unknown	gnl|CDD|213192
CP032698.1|AYG83186.1|6016537_6017179_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR	unknown	unknown	gnl|CDD|380056
CP032698.1|AYG83193.1|6024783_6025539_+|27-O-demethylrifamycin-SV-methyltransferase	unknown	unknown	gnl|CDD|369777
CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase	unknown	unknown	gnl|CDD|225035
CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein	unknown	unknown	gnl|CDD|378988
CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase	unknown	unknown	gnl|CDD|181145
CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein	unknown	unknown	gnl|CDD|224064
CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein	unknown	unknown	gnl|CDD|378961
CP032698.1|AYG83197.1|6028396_6029245_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
CP032698.1|AYG83195.1|6026707_6027277_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83196.1|6027289_6028300_-|Putative-coenzyme-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274647
CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase	unknown	unknown	gnl|CDD|143457
CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase	unknown	unknown	gnl|CDD|293811
CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein	unknown	unknown	gnl|CDD|366654
CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein	unknown	unknown	gnl|CDD|238362
CP032698.1|AYG83194.1|6025535_6026612_+|hypothetical-protein	unknown	unknown	gnl|CDD|273702
CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein	unknown	unknown	gnl|CDD|223692
CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein	unknown	unknown	gnl|CDD|370813

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83192.1|6023304_6024627_+|Glycogen-synthase	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.55441e-66
CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD	gnl|CDD|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	5.4498e-79
CP032698.1|AYG83196.1|6027289_6028300_-|Putative-coenzyme-F420-dependent-oxidoreductase	gnl|CDD|274647	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family. Members of this protein family are predicted to be oxidoreductases dependent on coenzyme F420. The family includes a single member in Mycobacterium tuberculosis (Rv3520c/MT3621) but four in Mycobacterium smegmatis. Prediction that this family is F420-dependent is based primarily on Partial Phylogenetic Profiling vs. F420 biosynthesis. [Unknown function, Enzymes of unknown specificity].	4.49334e-159
CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR	gnl|CDD|380056	pfam17925, TetR_C_20, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present the transcriptional regulator KstR that regulates a large set of genes responsible for cholesterol catabolism. This is important for Mycobacterium tuberculosis during infection, both at an early stage in the macrophage phagosome and later within the necrotic granuloma.	1.91136e-36
CP032698.1|AYG83193.1|6024783_6025539_+|27-O-demethylrifamycin-SV-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.8191e-27
CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.02866e-95
CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein	gnl|CDD|378988	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase. Pyridoxamine 5'-phosphate oxidase is a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). This entry contains several pyridoxamine 5'-phosphate oxidases, and related proteins.	5.6221e-39
CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase	gnl|CDD|143457	cd07139, ALDH_AldA-Rv0768, Mycobacterium tuberculosis aldehyde dehydrogenase AldA-like. The Mycobacterium tuberculosis NAD+-dependent, aldehyde dehydrogenase PDB structure, 3B4W, and the Mycobacterium tuberculosis H37Rv aldehyde dehydrogenase AldA (locus Rv0768) sequence, as well as the Rhodococcus rhodochrous ALDH involved in haloalkane catabolism, and other similar sequences, are included in this CD.	0
CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein	gnl|CDD|224064	COG1141, Fer, Ferredoxin [Energy production and conversion].	4.22638e-08
CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein	gnl|CDD|378961	pfam12822, ECF_trnsprt, ECF transporter, substrate-specific component. Energy-coupling factor (ECF) transporters consist of a substrate-specific component (known as the S component), and an energy-coupling module. The substrate-binding component is a small integral membrane protein which captures specific substrates and forms an active transporter in the presence of the energy-coupling AT module.	7.57278e-15
CP032698.1|AYG83197.1|6028396_6029245_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000217107
CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase	gnl|CDD|293811	cd07725, TTHA1429-like_MBL-fold, uncharacterized Thermus thermophilus TTHA1429 and related proteins; MBL-fold metallo hydrolase domain. Includes the MBL-fold metallo hydrolase domain of uncharacterized Thermus thermophilus TTHA1429 and related proteins. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	7.98134e-37
CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase	gnl|CDD|181145	PRK07850, PRK07850, steroid 3-ketoacyl-CoA thiolase.	0
CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein	gnl|CDD|366654	pfam01464, SLT, Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.	7.14623e-05
CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein	gnl|CDD|238362	cd00688, ISOPREN_C2_like, This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate complement. Class II terpene cyclases include squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY), these integral membrane proteins catalyze a cationic cyclization cascade converting linear triterpenes to fused ring compounds. The protein prenyltransferases include protein farnesyltransferase (FTase) and geranylgeranyltransferase types I and II (GGTase-I and GGTase-II) which catalyze the carboxyl-terminal lipidation of Ras, Rab, and several other cellular signal transduction proteins, facilitating membrane associations and specific protein-protein interactions. Alpha (2)-M is a major carrier protein in serum and involved in the immobilization and entrapment of proteases. PZP is a pregnancy associated protein. Alpha (2)-M and PZP are known to bind to and, may modulate, the activity of placental protein-14 in T-cell growth and cytokine production thereby protecting the allogeneic fetus from attack by the maternal immune system.	8.98769e-09
CP032698.1|AYG83194.1|6025535_6026612_+|hypothetical-protein	gnl|CDD|273702	TIGR01577, Uncharacterized_glycosyl_hydrolase_MJ1610, oligosaccharide amylase. The name of this type of amylase is based on the characterization of an glucoamylase family enzyme from Thermoactinomyces vulgaris. The T. vulgaris enzyme was expressed in E. coli and, like other glucoamylases, it releases beta-D-glucose from starch. However, unlike previously characterized glucoamylases, this T. vulgaris amylase hydrolyzes maltooligosaccharides (maltotetraose, maltose) more efficiently than starch (1), indicating this enzyme belongs to a class of glucoamylase-type enzymes with oligosaccharide-metabolizing activity.	9.4712e-13
CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein	gnl|CDD|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	2.92569e-10
CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein	gnl|CDD|370813	pfam10092, DUF2330, Uncharacterized protein conserved in bacteria (DUF2330). Members of this family of hypothetical bacterial proteins have no known function.	3.42283e-84

Protein sequences

>CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein
MTVRRSAAALTAALAAATAVLGGAAPAAFADGTPSPAALPPGLYGTKDPQFDGVFRQSLAFLAQEKTNVKPAEQAIAWLAGQQCADGSFTSFRADTATACDPKKLDTNATAAAVQAFVAVGGHADAIKKGVSWLKSVQQDDGGWPYTPGMGGSDSNSTAIVVGALAAAGEKPADVKSAKGGKTPFDALLTFALPCDDPAGPGAFAFQPDPKTQKLYANADATAAAVTGALGKGLTAGAGPADAKGTACERATTPEQAAHNGSAYLAKTLAPTGFLKSAMPGATDQPDFGNTADAVVALAAAGQTQQAKASADWLAKNAGAWAKENGPAAYAQLVFAADATGADPNNFGGLNLVTSLNATGPAPQTAVTSTPSAQTSHSKDDDGISVWWIVGAGLVAGIGVGFLISGRKKNQRL
>CP032698.1|AYG83186.1|6016537_6017179_-|hypothetical-protein
MRTRLAAFAAPLLALVVLATGAGPAQAAGYRYWAFWDLAGDAWTYATQGPASAHPGDGSVQGFRFAVSADSRDASQPRTAPSFEAVCGTTPTKDGTKRVALVIDFGTPEDATPGETPPAARNACAQVPPDATTADALAAVAKPLRYNSAALLCAIGGYPRTGCGEQVADPSAPKAEPANTGHDSGPSVGLLAGVAAVLALGAAAIWQARRRRN
>CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein
MHPGAWWLWALGLATAASRTNNPLLLGLLVGVAGYVVAARKTDAPWARSYTAFIKIGLFVVGIRLAFNVVLGSPIPGSHTLFTLPQLPLPDWAKGIRVGGRVTAEGMLFALYDGARLATLLICVGAANALANPARLLKSLPGALYEAGVAVVVAMTFAPNMVADVVRLRTARRLRGRPTGGLRAIAQIGLPVLEGALERSVAVAASMDARGYGRTAQVPAPVRLTTTVLTLGGLLGVCAGTYGLLASEGAGYGLPVLAGGVLASLAGLRLGGRRQLRTRYRPDRWGVRSWLVAGSGVAVAGLLLWTGTYAPEALTLGVVPLAAPSLPLWPALSLLAGLLPAFVAPVPPKESP
>CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD
MIRFENVSVTYDGADEATVRDVELAIPEGELVLLVGPSGVGKSTLLGTVSGLVPHFTGGTLRGRVTVDGRDTRTHKPRELADLVGTVGQDPLAHFVTDTVEDELAYGMESLGLAPAVMRRRVEETLDLLGLAELRDRPIATLSGGQQQRVAIGSVLTPHPKVLVLDEPTSALDPAAAEDVLSVLQRLVHDLGTTVLLAEHRLERVVQYADQVVLLPSPGAPPMMGTPADIMKVSPVHPPVVALGHLAGWTPLPLSVRDARRRSGPLRTELSTRVAAEPRTEARPAEPRPRAAAPRTLTRFFRRPQTPPAPTGTATATALGVRRGRVEALRRVDLTVAPGEIIALMGRNGAGKSTLLNTLVGMVEPTTGSVTVGGRTPHRTPPAELIREVGLVPQEPRDLLYANTVAAECAAADADAGAAPGSCRSLVSALLPGVRDDTHPRDLSEGQRLALALAIVLTGRPPLLLLDEPTRGLDYAAKARLVEVLRALAAEGHAIVLATHDVELAAELAHRVVILAGGEVVADGPTAEVVVSSPAFAPQIAKVLAPQHWLTVSQVREALS
>CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein
MTHTTEPPEPTGPAKRTRPDHAGRAVPAVRLGPRAVVALSLITLIGIAVFGWPLLADANSGLAHARDAPWLFAALLPLLVGVVIATIADDGMDAKAVAMLGVLAAVGAALRPLGAGTAGLEPMFFLMVLSGRVLGPGFGFVLGSVTMFASALLTGGVGPWMPFQMLAMGWFTMGAGLLPGPHRLRGRAECALLALYGALASFAYGTVMNLQGWTFIGGLSSGISFHPGDPLHDNLIRFFAYCAATSLGWDLGRAALTVVLTLTLGTTLLKALRRATRRAAFEAQVTFED
>CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein
MPPRLGFALSFAARFTARKKSVAAAGATLLAASGVALAAVPAQAAPTSAQAIARQMMPSDQFQCFSKIVNHESGWNPSATNASSGAYGLVQALPGSKMASAGADWQTNPATQIKWGLGYMNERYGSPCGAWSFWQQNNWY
>CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase
MAAEPVIVEAVRTPIGKRGGALANLHPAYLLGETYRELLGRTGIHADCVEQIVGGTVTHAGEQSMNPARNAWLAVGLPYETAATTVDCQCGSSQQASHMVANMIAAGVIDVGISCGVEAMSRVPLGSGSKHGPGKPWPDEWNVDLPNQFEAAERIARNRGLTRERVDALGLMSQERAAVAWAEERFKRETFAVQVPTTEEEQAAGQGMWRLVDRDEGLRDTSMEALGRLKPVMPTAVHTAGNSSQISDGSAAIMWASKRMARALKLKPRARIVAQALVGADPHFHLDGPIDATRAVLGKAGMSLRDIDLVEINEAFASVVLSWAQVFEQDLEKVNVNGGAIALGHPVGATGARLIATALHELERRGKEFALVTMCAGGALATATILQRL
>CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase
MRCPHLPDGFDFTDPDLLQSRVPHPEFAELRQTAPVWWCAQPTGISGFQDDGYWAVTRHADVKYVSTHPELFSSHTNTAVIRFNESISREQIDVQKLIMLNMDPPEHTRVRQIVQRGFTPRAIRSLEGALRDRARGIVDAALSEADKNDGAFDFVTQIAVELPLQAIAELIGVPQEDRTKIFDWSNKMAAYDDPEYAITEEIGAEAAMELVSYAMNLAAARKECPAKDIVSQLVAAEGEGNLLSDEFGFFVILLAVAGNETTRNAISHGMHAFLTHPDQWELYKRERPVTAAEEIVRWATPVVAFQRTATQDTELGGQKIKAGDRVGIFYSSANNDPEVFEEPDRFDITRDPNPHLGFGGGGPHFCLGKSLAVLEINLIFNAIADVLPDLRLAGDPRRLRSAWLNGIKGLRVIHG
>CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein
MDVQQPDQHARPEPAAPVGLAVTERTRHRRLREQGSTRVEDLDAILKAGFVCHLGVVVDGTPMVVPTVYGVDFATRTLFLHGSVASRSIVAAPRATVCVTVTHIDGLVLARSVFEHGVNYRSAMVYAVPRLITEGDELLHGLRVLTEHCAPGQWDYARRPNSRELAATSLLALSLEEASVKTASGPPEDGQGPDGELGLWAGVVPLHSHFGPPEPDPALAAGIAMPGHVALLGTGRDTRP
>CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein
MRDGTGRLRRTGDGRRPWRRVLLVALALVALQLGSLVAPAYACGCGAMVPQSGRQLSVRQETSAVRWDGHHEQIVMRLTVDGNAPQAAWIMPVPSRATVKLGDRQLFDELERLSAPVHRTRTYFWPRSGDWPLARDRSVGDGAPRPAAKPPVEVVGRERLGPFDVARLTASDPTALRDWLSRNGFQLPPALSTELRPYVDQKWEYVAIRLAPDRPGRALGGPLDPLSLSFASDRLIYPMRLSRLAKTPQTLDLYVLADHRMETASTIGGDRPETLFAGDVEHPSGPLAELTGGTGPVYLTALTQFFTRPSRITGDHELTRAADDTGFQRTWYTDELMTVGGAPLWLVTVGGALAVLLAGALGTVLAVRGRRRRRGDAQLPEPVSHSRPA
>CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase
MPQEPAAPQVSDHGGGVHSIKVPIPDNPLGHTLVHLVDTDRGPVLIDTGWDDPASWNTLTAGLRALGTDVSAVHGVVITHHHPDHHGLSGQVREASGAWIAMHAADAAVVRRTREAQPGVWLDYLCAKLTAVGAPDEHIAPLRQARASGRARTLPGLRAALPDREIVPGDLLPLAGRRLRAIWTPGHTPGHVCLHLEEAHPSQLPGHGRLFSGDHLLPGITPHIGLYEDPDDGESTDPLGDYLDSLERVGRLGVAEVLPAHQHAFAEPGVRVRELLAHHEERLAGLLSLLSAPLTPWELAERMEWNRPWGQIPDGSRTIAVSEAEAHVRRLEKLGRVVRVGGSPARYHAV
>CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase
MTELVEHGQLFIGGELTDPLGSDVIEVISPHTEQVIGRVPHACRADVDRAVAAARTAFDTGPWARATPEERIEVVSRIKDAILARHEEIARCISAQNGSPYSWSVLAQALGAMMVWDSAITVARRFPYEERRSGALGPLLVRREPVGVVAAVVPWNVPQFVAAAKLGPALLTGCSVILKPSPETPLDAYILGEIAAEAGLPEGVLSILPADREVSEYLVGHPGVDKVSFTGSVAAGKRVMEVAARNLTRVTLELGGKSAAVILPDADLETTVAGVASAAWMNNGQACVAQTRILAPRARYEEFAEAFAAAAGALVVGDPLDPATQVGPLVAERQRQRSLDYIRIGQEEGAKILSGGGRPAGLERGWYVEPTLFGGVDNTMRIAREEIFGPVICLLPYGDEAEALGIANDSEYGLSGSVWTGDVEHGIDFGRRVRTGTFNVNTFSLDMLGPFGGYKSSGLGREFGPEGFGEYLEHKMIHLPAGHGGE
>CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein
MGDRWHVEVDRSVCIGSGMCVNHAPAAFELDSARQSQPREPDTDAGEQVLAAAEGCPVEAILITLLGSGETVFPPED
>CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR
MTAEAKAAIPATPPLTERQEARRRRILHASAQLASRGGFDAVQMREVAEAAGVALGTLYRYFPSKIHLLVATMQDQLQHLHGTLRKHPPSGAGSAERVAETLMRAFRALQREPHLADAMVRALTFADRSVSPEVDTVSRQTTAIILDAVGLEHPTPEQLSAVRVIEHTWHSALITWLSGRASIAQVKIDIETVCKLIDLTTPPNP
>CP032698.1|AYG83192.1|6023304_6024627_+|Glycogen-synthase
MTAEAIEASPRTGGDDRAGERPLRIALLTYKGNPFCGGQGVYVRHLSRELARLGHSVEVIGAQPYPVLDEGVPLTELPSLDLYRSPDPFRTPARDEYRDWIDRLEVAAMRTGGFPEPLTFSLRARRHLAARRGEFDVIHDNQTLGYGLLGDVGAPLVTTIHHPITVDRRLELDAAPDWKRRASVRRWYGFTQMQKRVARRLPSVLTVSGTSKGEIVDHLGVREERIEVVHIGADTGLWSPDAAVAEVPGRIVTTSSADVPLKGLVFLVEALAKLRTEHPDAHLVVVGKRAEDGPVAQAIEKYGLGHAVEFVKGITDAELVDLVRSAQVSCVPSLYEGFSLPAAEAMATGTPLLATTGGAIPEVAGPDGETCLAVPPGDAGALAAGLARLLGDPALRRRLGAAGRERVLERFTWRRAALGTADLYRSAIAAQGRSARKAAR
>CP032698.1|AYG83193.1|6024783_6025539_+|27-O-demethylrifamycin-SV-methyltransferase
MLTVDFSRFPLAPGDRVLDLGCGAGRHAFECYRRGAQVVALDQNAEEIREVATWFAAMKEAGEAPEGATATAMEGDALNLPFPDESFDVVIISEVMEHIPDDKGVLAEMVRVLKPGGRIAVTVPRYGPEKVCWALSDAYHEVEGGHIRIYKADELIGKMRQAGLKPYGTHHAHALHSPYWWLKCAFGVDNDKALPVRAYHQLLVWDIMKTPGISTVTRLAERALNPVVGKSFVAYATKPHLPALPEKSAAK
>CP032698.1|AYG83194.1|6025535_6026612_+|hypothetical-protein
MTSPERTEHLVLPGVLTAEQAGQTVSALLDAQRADGAIPWFRGHHLDPWDHTEAAMALDAAGEHAAAERAYEWLARHQNTDGSWYAAYHDGEHDRVTDGCRESNFVAYVAVGVWHHYLATGDDTFLDRMWPTVFAAVEWVLALQQGGGQIGWKREEDGTPVTDALLTGSSSVHHALRCALAIAEQREEPQPDWELATGALAHAIQHHPERFLDKARYSMDWYYPVLGGAVTGAAATARIDSRWEEFVVPGLGVRCVLPNPWVTGGESCELALALWATGESDRALEILQSIQHLRDPATGMYWTGYVFEGNRAVWPEELTTWTAGSLLLAVAALGGDEATGAVFGGERLPRGLAPYCCG
>CP032698.1|AYG83195.1|6026707_6027277_+|hypothetical-protein
MASTFPIRRIVVAVVLSCAVLVSTTACGGETRSTQSAALTAAESSPSPSASAERQKLAKTRFVANAGLAAGAAYQWIVKPYKAGKFKKGAKGRTFALVKAGLAGAFTYNRLKAASENAKGDPLLSKAVAPLTSGIESLKGLGGKLRKGDAGDADVGMFEKMINGVKDAGQKAGAPVKDQVPSAGQLSGG
>CP032698.1|AYG83196.1|6027289_6028300_-|Putative-coenzyme-F420-dependent-oxidoreductase
MRLGLALGYWGRGPNPAHLELARAAEEFGYHSVWTAEAWGSDAFTPLTWIAAHTSTIRLGTAVAQMAARTPTATAMHALTLDHLSGGRMMLGLGLSGPQVVEGWYGRPFPSSPLTATREYVEVIRQVLRREGPVELDGRFHAHPYGGADGTGLGKPLKAITHPLRPDLPVLLGAEGPKNIAQTTRIADGWLPLYWSPTRTDVYEASLTGLREGFLVAPMVRAQVCDDVAEGLLPVKAMLGFYIGGMGHAARNFHADLMARMGYGDAAHHIQELFLAGRRDEAVRAVPDAFADEISLVGPRQRIAERLELWRAGPVTDLLVTSPDPTTLRVLAELNT
>CP032698.1|AYG83197.1|6028396_6029245_-|hypothetical-protein
MNIRSLTRGDGVVIGAAVVLFIASFLSLTSAPSCAGQFCPRADEPNAWDSLSLLMSMFLAGIIGAVLVVVGRSLPQPKKVAGLDLTQFGVAFTIFAAWTAFWTIIDAHGSGAGMILGLIATLVLAAAAVASPLIGALKAPLMGTPSPAAPQPYGYPGVAQPAGGYGYPAAQQPYGAHPGDPSLGGQPAAQAQPFGAQAPAADPNKDSQAQPAAAPAGDFAPFWFAVPVARPLYAEDGSPTPIAELAPGTWYLAVDQRGPALVAQTQDGRRGVLQDTTGIQRG

Crispr_ID: CP032698_81

• CRISPR_ID: CP032698_81
• CRISPR_location: 6018730-6018868
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_81

Consensus_repeat	Method
GTCTC----------------GCGCAGTTCCCCGCGCCCCT	PILER-CR

spacers of CP032698_81

>81.1|6018757|32|CP032698|PILER-CR
ATGAAACCCGCCTTCGTGTGCGGACCGTGCCC
>81.2|6018816|32|CP032698|PILER-CR
GGCAGTACTCGTGCTGGCCCGCGTGAGGGTTG

CRISPR arrays and Neighbor proteins around CP032698_81

CRISPR arrays

The CRISPR arrays of CP032698_81

>merge|CP032698|81|6018730-6018868|PILER-CR
GTCCCGCGCAGTTCCCCGCGCCCCCATGAAACCCGCCTTCGTGTGCGGACCGTGCCCGCTTCTCGCGCAGTTCCCCGCGCCCCTGGCAGTACTCGTGCTGGCCCGCGTGAGGGTTGGTCGCGCAGTTCCCCGCGCCCCT

>CP032698|81|22|6018730-6018868|PILER-CR
GTCCCGCGCAGTTCCCCGCGCCCCCAT	GAAACCCGCCTTCGTGTGCGGACCGTGCCCGC
TTCTCGCGCAGTTCCCCGCGCCCCTGG	CAGTACTCGTGCTGGCCCGCGTGAGGGTTGGT
CGCGCAGTTCCCCGCGCCCCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83192.1|6023304_6024627_+|Glycogen-synthase	unknown	unknown	gnl|CDD|340831
CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD	unknown	unknown	gnl|CDD|213192
CP032698.1|AYG83186.1|6016537_6017179_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR	unknown	unknown	gnl|CDD|380056
CP032698.1|AYG83193.1|6024783_6025539_+|27-O-demethylrifamycin-SV-methyltransferase	unknown	unknown	gnl|CDD|369777
CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase	unknown	unknown	gnl|CDD|225035
CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein	unknown	unknown	gnl|CDD|378988
CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase	unknown	unknown	gnl|CDD|181145
CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein	unknown	unknown	gnl|CDD|224064
CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein	unknown	unknown	gnl|CDD|378961
CP032698.1|AYG83197.1|6028396_6029245_-|hypothetical-protein	unknown	unknown	gnl|CDD|236090
CP032698.1|AYG83195.1|6026707_6027277_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83196.1|6027289_6028300_-|Putative-coenzyme-F420-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274647
CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase	unknown	unknown	gnl|CDD|143457
CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase	unknown	unknown	gnl|CDD|293811
CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein	unknown	unknown	gnl|CDD|366654
CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein	unknown	unknown	gnl|CDD|238362
CP032698.1|AYG83194.1|6025535_6026612_+|hypothetical-protein	unknown	unknown	gnl|CDD|273702
CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein	unknown	unknown	gnl|CDD|223692
CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein	unknown	unknown	gnl|CDD|370813

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83192.1|6023304_6024627_+|Glycogen-synthase	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.55441e-66
CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD	gnl|CDD|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	5.4498e-79
CP032698.1|AYG83196.1|6027289_6028300_-|Putative-coenzyme-F420-dependent-oxidoreductase	gnl|CDD|274647	TIGR03559, F420_Rv3520c, probable F420-dependent oxidoreductase, Rv3520c family. Members of this protein family are predicted to be oxidoreductases dependent on coenzyme F420. The family includes a single member in Mycobacterium tuberculosis (Rv3520c/MT3621) but four in Mycobacterium smegmatis. Prediction that this family is F420-dependent is based primarily on Partial Phylogenetic Profiling vs. F420 biosynthesis. [Unknown function, Enzymes of unknown specificity].	4.49334e-159
CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR	gnl|CDD|380056	pfam17925, TetR_C_20, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present the transcriptional regulator KstR that regulates a large set of genes responsible for cholesterol catabolism. This is important for Mycobacterium tuberculosis during infection, both at an early stage in the macrophage phagosome and later within the necrotic granuloma.	1.91136e-36
CP032698.1|AYG83193.1|6024783_6025539_+|27-O-demethylrifamycin-SV-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.8191e-27
CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase	gnl|CDD|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.02866e-95
CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein	gnl|CDD|378988	pfam12900, Pyridox_ox_2, Pyridoxamine 5'-phosphate oxidase. Pyridoxamine 5'-phosphate oxidase is a FMN flavoprotein that catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP). This entry contains several pyridoxamine 5'-phosphate oxidases, and related proteins.	5.6221e-39
CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase	gnl|CDD|143457	cd07139, ALDH_AldA-Rv0768, Mycobacterium tuberculosis aldehyde dehydrogenase AldA-like. The Mycobacterium tuberculosis NAD+-dependent, aldehyde dehydrogenase PDB structure, 3B4W, and the Mycobacterium tuberculosis H37Rv aldehyde dehydrogenase AldA (locus Rv0768) sequence, as well as the Rhodococcus rhodochrous ALDH involved in haloalkane catabolism, and other similar sequences, are included in this CD.	0
CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein	gnl|CDD|224064	COG1141, Fer, Ferredoxin [Energy production and conversion].	4.22638e-08
CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein	gnl|CDD|378961	pfam12822, ECF_trnsprt, ECF transporter, substrate-specific component. Energy-coupling factor (ECF) transporters consist of a substrate-specific component (known as the S component), and an energy-coupling module. The substrate-binding component is a small integral membrane protein which captures specific substrates and forms an active transporter in the presence of the energy-coupling AT module.	7.57278e-15
CP032698.1|AYG83197.1|6028396_6029245_-|hypothetical-protein	gnl|CDD|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000217107
CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase	gnl|CDD|293811	cd07725, TTHA1429-like_MBL-fold, uncharacterized Thermus thermophilus TTHA1429 and related proteins; MBL-fold metallo hydrolase domain. Includes the MBL-fold metallo hydrolase domain of uncharacterized Thermus thermophilus TTHA1429 and related proteins. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	7.98134e-37
CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase	gnl|CDD|181145	PRK07850, PRK07850, steroid 3-ketoacyl-CoA thiolase.	0
CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein	gnl|CDD|366654	pfam01464, SLT, Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.	7.14623e-05
CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein	gnl|CDD|238362	cd00688, ISOPREN_C2_like, This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate complement. Class II terpene cyclases include squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY), these integral membrane proteins catalyze a cationic cyclization cascade converting linear triterpenes to fused ring compounds. The protein prenyltransferases include protein farnesyltransferase (FTase) and geranylgeranyltransferase types I and II (GGTase-I and GGTase-II) which catalyze the carboxyl-terminal lipidation of Ras, Rab, and several other cellular signal transduction proteins, facilitating membrane associations and specific protein-protein interactions. Alpha (2)-M is a major carrier protein in serum and involved in the immobilization and entrapment of proteases. PZP is a pregnancy associated protein. Alpha (2)-M and PZP are known to bind to and, may modulate, the activity of placental protein-14 in T-cell growth and cytokine production thereby protecting the allogeneic fetus from attack by the maternal immune system.	8.98769e-09
CP032698.1|AYG83194.1|6025535_6026612_+|hypothetical-protein	gnl|CDD|273702	TIGR01577, Uncharacterized_glycosyl_hydrolase_MJ1610, oligosaccharide amylase. The name of this type of amylase is based on the characterization of an glucoamylase family enzyme from Thermoactinomyces vulgaris. The T. vulgaris enzyme was expressed in E. coli and, like other glucoamylases, it releases beta-D-glucose from starch. However, unlike previously characterized glucoamylases, this T. vulgaris amylase hydrolyzes maltooligosaccharides (maltotetraose, maltose) more efficiently than starch (1), indicating this enzyme belongs to a class of glucoamylase-type enzymes with oligosaccharide-metabolizing activity.	9.4712e-13
CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein	gnl|CDD|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	2.92569e-10
CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein	gnl|CDD|370813	pfam10092, DUF2330, Uncharacterized protein conserved in bacteria (DUF2330). Members of this family of hypothetical bacterial proteins have no known function.	3.42283e-84

Protein sequences

>CP032698.1|AYG83187.1|6017178_6018420_-|hypothetical-protein
MTVRRSAAALTAALAAATAVLGGAAPAAFADGTPSPAALPPGLYGTKDPQFDGVFRQSLAFLAQEKTNVKPAEQAIAWLAGQQCADGSFTSFRADTATACDPKKLDTNATAAAVQAFVAVGGHADAIKKGVSWLKSVQQDDGGWPYTPGMGGSDSNSTAIVVGALAAAGEKPADVKSAKGGKTPFDALLTFALPCDDPAGPGAFAFQPDPKTQKLYANADATAAAVTGALGKGLTAGAGPADAKGTACERATTPEQAAHNGSAYLAKTLAPTGFLKSAMPGATDQPDFGNTADAVVALAAAGQTQQAKASADWLAKNAGAWAKENGPAAYAQLVFAADATGADPNNFGGLNLVTSLNATGPAPQTAVTSTPSAQTSHSKDDDGISVWWIVGAGLVAGIGVGFLISGRKKNQRL
>CP032698.1|AYG83186.1|6016537_6017179_-|hypothetical-protein
MRTRLAAFAAPLLALVVLATGAGPAQAAGYRYWAFWDLAGDAWTYATQGPASAHPGDGSVQGFRFAVSADSRDASQPRTAPSFEAVCGTTPTKDGTKRVALVIDFGTPEDATPGETPPAARNACAQVPPDATTADALAAVAKPLRYNSAALLCAIGGYPRTGCGEQVADPSAPKAEPANTGHDSGPSVGLLAGVAAVLALGAAAIWQARRRRN
>CP032698.1|AYG83185.1|6015326_6016385_-|hypothetical-protein
MHPGAWWLWALGLATAASRTNNPLLLGLLVGVAGYVVAARKTDAPWARSYTAFIKIGLFVVGIRLAFNVVLGSPIPGSHTLFTLPQLPLPDWAKGIRVGGRVTAEGMLFALYDGARLATLLICVGAANALANPARLLKSLPGALYEAGVAVVVAMTFAPNMVADVVRLRTARRLRGRPTGGLRAIAQIGLPVLEGALERSVAVAASMDARGYGRTAQVPAPVRLTTTVLTLGGLLGVCAGTYGLLASEGAGYGLPVLAGGVLASLAGLRLGGRRQLRTRYRPDRWGVRSWLVAGSGVAVAGLLLWTGTYAPEALTLGVVPLAAPSLPLWPALSLLAGLLPAFVAPVPPKESP
>CP032698.1|AYG83184.1|6013647_6015330_-|Putative-HMP/thiamine-import-ATP-binding-protein-YkoD
MIRFENVSVTYDGADEATVRDVELAIPEGELVLLVGPSGVGKSTLLGTVSGLVPHFTGGTLRGRVTVDGRDTRTHKPRELADLVGTVGQDPLAHFVTDTVEDELAYGMESLGLAPAVMRRRVEETLDLLGLAELRDRPIATLSGGQQQRVAIGSVLTPHPKVLVLDEPTSALDPAAAEDVLSVLQRLVHDLGTTVLLAEHRLERVVQYADQVVLLPSPGAPPMMGTPADIMKVSPVHPPVVALGHLAGWTPLPLSVRDARRRSGPLRTELSTRVAAEPRTEARPAEPRPRAAAPRTLTRFFRRPQTPPAPTGTATATALGVRRGRVEALRRVDLTVAPGEIIALMGRNGAGKSTLLNTLVGMVEPTTGSVTVGGRTPHRTPPAELIREVGLVPQEPRDLLYANTVAAECAAADADAGAAPGSCRSLVSALLPGVRDDTHPRDLSEGQRLALALAIVLTGRPPLLLLDEPTRGLDYAAKARLVEVLRALAAEGHAIVLATHDVELAAELAHRVVILAGGEVVADGPTAEVVVSSPAFAPQIAKVLAPQHWLTVSQVREALS
>CP032698.1|AYG83183.1|6012781_6013651_-|hypothetical-protein
MTHTTEPPEPTGPAKRTRPDHAGRAVPAVRLGPRAVVALSLITLIGIAVFGWPLLADANSGLAHARDAPWLFAALLPLLVGVVIATIADDGMDAKAVAMLGVLAAVGAALRPLGAGTAGLEPMFFLMVLSGRVLGPGFGFVLGSVTMFASALLTGGVGPWMPFQMLAMGWFTMGAGLLPGPHRLRGRAECALLALYGALASFAYGTVMNLQGWTFIGGLSSGISFHPGDPLHDNLIRFFAYCAATSLGWDLGRAALTVVLTLTLGTTLLKALRRATRRAAFEAQVTFED
>CP032698.1|AYG83182.1|6012049_6012472_-|hypothetical-protein
MPPRLGFALSFAARFTARKKSVAAAGATLLAASGVALAAVPAQAAPTSAQAIARQMMPSDQFQCFSKIVNHESGWNPSATNASSGAYGLVQALPGSKMASAGADWQTNPATQIKWGLGYMNERYGSPCGAWSFWQQNNWY
>CP032698.1|AYG83181.1|6010303_6011473_+|Steroid-3-ketoacyl-CoA-thiolase
MAAEPVIVEAVRTPIGKRGGALANLHPAYLLGETYRELLGRTGIHADCVEQIVGGTVTHAGEQSMNPARNAWLAVGLPYETAATTVDCQCGSSQQASHMVANMIAAGVIDVGISCGVEAMSRVPLGSGSKHGPGKPWPDEWNVDLPNQFEAAERIARNRGLTRERVDALGLMSQERAAVAWAEERFKRETFAVQVPTTEEEQAAGQGMWRLVDRDEGLRDTSMEALGRLKPVMPTAVHTAGNSSQISDGSAAIMWASKRMARALKLKPRARIVAQALVGADPHFHLDGPIDATRAVLGKAGMSLRDIDLVEINEAFASVVLSWAQVFEQDLEKVNVNGGAIALGHPVGATGARLIATALHELERRGKEFALVTMCAGGALATATILQRL
>CP032698.1|AYG83180.1|6008816_6010064_-|Steroid-C26-monooxygenase
MRCPHLPDGFDFTDPDLLQSRVPHPEFAELRQTAPVWWCAQPTGISGFQDDGYWAVTRHADVKYVSTHPELFSSHTNTAVIRFNESISREQIDVQKLIMLNMDPPEHTRVRQIVQRGFTPRAIRSLEGALRDRARGIVDAALSEADKNDGAFDFVTQIAVELPLQAIAELIGVPQEDRTKIFDWSNKMAAYDDPEYAITEEIGAEAAMELVSYAMNLAAARKECPAKDIVSQLVAAEGEGNLLSDEFGFFVILLAVAGNETTRNAISHGMHAFLTHPDQWELYKRERPVTAAEEIVRWATPVVAFQRTATQDTELGGQKIKAGDRVGIFYSSANNDPEVFEEPDRFDITRDPNPHLGFGGGGPHFCLGKSLAVLEINLIFNAIADVLPDLRLAGDPRRLRSAWLNGIKGLRVIHG
>CP032698.1|AYG83179.1|6007917_6008640_-|hypothetical-protein
MDVQQPDQHARPEPAAPVGLAVTERTRHRRLREQGSTRVEDLDAILKAGFVCHLGVVVDGTPMVVPTVYGVDFATRTLFLHGSVASRSIVAAPRATVCVTVTHIDGLVLARSVFEHGVNYRSAMVYAVPRLITEGDELLHGLRVLTEHCAPGQWDYARRPNSRELAATSLLALSLEEASVKTASGPPEDGQGPDGELGLWAGVVPLHSHFGPPEPDPALAAGIAMPGHVALLGTGRDTRP
>CP032698.1|AYG83178.1|6006682_6007852_-|hypothetical-protein
MRDGTGRLRRTGDGRRPWRRVLLVALALVALQLGSLVAPAYACGCGAMVPQSGRQLSVRQETSAVRWDGHHEQIVMRLTVDGNAPQAAWIMPVPSRATVKLGDRQLFDELERLSAPVHRTRTYFWPRSGDWPLARDRSVGDGAPRPAAKPPVEVVGRERLGPFDVARLTASDPTALRDWLSRNGFQLPPALSTELRPYVDQKWEYVAIRLAPDRPGRALGGPLDPLSLSFASDRLIYPMRLSRLAKTPQTLDLYVLADHRMETASTIGGDRPETLFAGDVEHPSGPLAELTGGTGPVYLTALTQFFTRPSRITGDHELTRAADDTGFQRTWYTDELMTVGGAPLWLVTVGGALAVLLAGALGTVLAVRGRRRRRGDAQLPEPVSHSRPA
>CP032698.1|AYG83188.1|6019087_6020140_-|Hydroxyacylglutathione-hydrolase
MPQEPAAPQVSDHGGGVHSIKVPIPDNPLGHTLVHLVDTDRGPVLIDTGWDDPASWNTLTAGLRALGTDVSAVHGVVITHHHPDHHGLSGQVREASGAWIAMHAADAAVVRRTREAQPGVWLDYLCAKLTAVGAPDEHIAPLRQARASGRARTLPGLRAALPDREIVPGDLLPLAGRRLRAIWTPGHTPGHVCLHLEEAHPSQLPGHGRLFSGDHLLPGITPHIGLYEDPDDGESTDPLGDYLDSLERVGRLGVAEVLPAHQHAFAEPGVRVRELLAHHEERLAGLLSLLSAPLTPWELAERMEWNRPWGQIPDGSRTIAVSEAEAHVRRLEKLGRVVRVGGSPARYHAV
>CP032698.1|AYG83189.1|6020425_6021886_+|Geranial-dehydrogenase
MTELVEHGQLFIGGELTDPLGSDVIEVISPHTEQVIGRVPHACRADVDRAVAAARTAFDTGPWARATPEERIEVVSRIKDAILARHEEIARCISAQNGSPYSWSVLAQALGAMMVWDSAITVARRFPYEERRSGALGPLLVRREPVGVVAAVVPWNVPQFVAAAKLGPALLTGCSVILKPSPETPLDAYILGEIAAEAGLPEGVLSILPADREVSEYLVGHPGVDKVSFTGSVAAGKRVMEVAARNLTRVTLELGGKSAAVILPDADLETTVAGVASAAWMNNGQACVAQTRILAPRARYEEFAEAFAAAAGALVVGDPLDPATQVGPLVAERQRQRSLDYIRIGQEEGAKILSGGGRPAGLERGWYVEPTLFGGVDNTMRIAREEIFGPVICLLPYGDEAEALGIANDSEYGLSGSVWTGDVEHGIDFGRRVRTGTFNVNTFSLDMLGPFGGYKSSGLGREFGPEGFGEYLEHKMIHLPAGHGGE
>CP032698.1|AYG83190.1|6021885_6022119_+|hypothetical-protein
MGDRWHVEVDRSVCIGSGMCVNHAPAAFELDSARQSQPREPDTDAGEQVLAAAEGCPVEAILITLLGSGETVFPPED
>CP032698.1|AYG83191.1|6022441_6023059_-|HTH-type-transcriptional-repressor-KstR
MTAEAKAAIPATPPLTERQEARRRRILHASAQLASRGGFDAVQMREVAEAAGVALGTLYRYFPSKIHLLVATMQDQLQHLHGTLRKHPPSGAGSAERVAETLMRAFRALQREPHLADAMVRALTFADRSVSPEVDTVSRQTTAIILDAVGLEHPTPEQLSAVRVIEHTWHSALITWLSGRASIAQVKIDIETVCKLIDLTTPPNP
>CP032698.1|AYG83192.1|6023304_6024627_+|Glycogen-synthase
MTAEAIEASPRTGGDDRAGERPLRIALLTYKGNPFCGGQGVYVRHLSRELARLGHSVEVIGAQPYPVLDEGVPLTELPSLDLYRSPDPFRTPARDEYRDWIDRLEVAAMRTGGFPEPLTFSLRARRHLAARRGEFDVIHDNQTLGYGLLGDVGAPLVTTIHHPITVDRRLELDAAPDWKRRASVRRWYGFTQMQKRVARRLPSVLTVSGTSKGEIVDHLGVREERIEVVHIGADTGLWSPDAAVAEVPGRIVTTSSADVPLKGLVFLVEALAKLRTEHPDAHLVVVGKRAEDGPVAQAIEKYGLGHAVEFVKGITDAELVDLVRSAQVSCVPSLYEGFSLPAAEAMATGTPLLATTGGAIPEVAGPDGETCLAVPPGDAGALAAGLARLLGDPALRRRLGAAGRERVLERFTWRRAALGTADLYRSAIAAQGRSARKAAR
>CP032698.1|AYG83193.1|6024783_6025539_+|27-O-demethylrifamycin-SV-methyltransferase
MLTVDFSRFPLAPGDRVLDLGCGAGRHAFECYRRGAQVVALDQNAEEIREVATWFAAMKEAGEAPEGATATAMEGDALNLPFPDESFDVVIISEVMEHIPDDKGVLAEMVRVLKPGGRIAVTVPRYGPEKVCWALSDAYHEVEGGHIRIYKADELIGKMRQAGLKPYGTHHAHALHSPYWWLKCAFGVDNDKALPVRAYHQLLVWDIMKTPGISTVTRLAERALNPVVGKSFVAYATKPHLPALPEKSAAK
>CP032698.1|AYG83194.1|6025535_6026612_+|hypothetical-protein
MTSPERTEHLVLPGVLTAEQAGQTVSALLDAQRADGAIPWFRGHHLDPWDHTEAAMALDAAGEHAAAERAYEWLARHQNTDGSWYAAYHDGEHDRVTDGCRESNFVAYVAVGVWHHYLATGDDTFLDRMWPTVFAAVEWVLALQQGGGQIGWKREEDGTPVTDALLTGSSSVHHALRCALAIAEQREEPQPDWELATGALAHAIQHHPERFLDKARYSMDWYYPVLGGAVTGAAATARIDSRWEEFVVPGLGVRCVLPNPWVTGGESCELALALWATGESDRALEILQSIQHLRDPATGMYWTGYVFEGNRAVWPEELTTWTAGSLLLAVAALGGDEATGAVFGGERLPRGLAPYCCG
>CP032698.1|AYG83195.1|6026707_6027277_+|hypothetical-protein
MASTFPIRRIVVAVVLSCAVLVSTTACGGETRSTQSAALTAAESSPSPSASAERQKLAKTRFVANAGLAAGAAYQWIVKPYKAGKFKKGAKGRTFALVKAGLAGAFTYNRLKAASENAKGDPLLSKAVAPLTSGIESLKGLGGKLRKGDAGDADVGMFEKMINGVKDAGQKAGAPVKDQVPSAGQLSGG
>CP032698.1|AYG83196.1|6027289_6028300_-|Putative-coenzyme-F420-dependent-oxidoreductase
MRLGLALGYWGRGPNPAHLELARAAEEFGYHSVWTAEAWGSDAFTPLTWIAAHTSTIRLGTAVAQMAARTPTATAMHALTLDHLSGGRMMLGLGLSGPQVVEGWYGRPFPSSPLTATREYVEVIRQVLRREGPVELDGRFHAHPYGGADGTGLGKPLKAITHPLRPDLPVLLGAEGPKNIAQTTRIADGWLPLYWSPTRTDVYEASLTGLREGFLVAPMVRAQVCDDVAEGLLPVKAMLGFYIGGMGHAARNFHADLMARMGYGDAAHHIQELFLAGRRDEAVRAVPDAFADEISLVGPRQRIAERLELWRAGPVTDLLVTSPDPTTLRVLAELNT
>CP032698.1|AYG83197.1|6028396_6029245_-|hypothetical-protein
MNIRSLTRGDGVVIGAAVVLFIASFLSLTSAPSCAGQFCPRADEPNAWDSLSLLMSMFLAGIIGAVLVVVGRSLPQPKKVAGLDLTQFGVAFTIFAAWTAFWTIIDAHGSGAGMILGLIATLVLAAAAVASPLIGALKAPLMGTPSPAAPQPYGYPGVAQPAGGYGYPAAQQPYGAHPGDPSLGGQPAAQAQPFGAQAPAADPNKDSQAQPAAAPAGDFAPFWFAVPVARPLYAEDGSPTPIAELAPGTWYLAVDQRGPALVAQTQDGRRGVLQDTTGIQRG

Crispr_ID: CP032698_83

• CRISPR_ID: CP032698_83
• CRISPR_location: 6062720-6062806
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_83

Consensus_repeat	Method
AGGGGCGCGGGGAACTGCGCGAGC	CRISPRCasFinder

spacers of CP032698_83

>83.1|6062744|39|CP032698|CRISPRCasFinder
AACCACGCACGACCCGAACCCGAAGTCGCCGGGCGGGCC

CRISPR arrays and Neighbor proteins around CP032698_83

CRISPR arrays

The CRISPR arrays of CP032698_83

>merge|CP032698|83|6062720-6062806|CRISPRCasFinder
AGGGGCGCGGGGAACTGCGCGAGCAACCACGCACGACCCGAACCCGAAGTCGCCGGGCGGGCCAGGGGCGCGGGGAACTGCGCGAGC

>CP032698|83|60|6062720-6062806|CRISPRCasFinder
AGGGGCGCGGGGAACTGCGCGAGC	AACCACGCACGACCCGAACCCGAAGTCGCCGGGCGGGCC
AGGGGCGCGGGGAACTGCGCGAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83229.1|6060563_6060722_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83225.1|6057234_6058557_+|Bicyclomycin-resistance-protein	unknown	unknown	gnl|CDD|340878
CP032698.1|AYG83236.1|6067436_6068099_-|Heme-oxygenase	unknown	unknown	gnl|CDD|350856
CP032698.1|AYG83240.1|6070984_6071587_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83222.1|6054705_6055029_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83235.1|6065968_6067114_-|Efem/EfeO-family-lipoprotein	unknown	unknown	gnl|CDD|225378
CP032698.1|AYG83232.1|6062837_6063746_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83228.1|6059586_6060369_-|hypothetical-protein	unknown	unknown	gnl|CDD|224747
CP032698.1|AYG83237.1|6068245_6069115_-|Methionine-aminopeptidase-2	unknown	unknown	gnl|CDD|235576
CP032698.1|AYG83226.1|6058737_6058950_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83227.1|6059106_6059586_+|hypothetical-protein	unknown	unknown	gnl|CDD|286344
CP032698.1|AYG83239.1|6069607_6070906_-|Enterobactin-exporter-EntS	unknown	unknown	gnl|CDD|340863
CP032698.1|AYG83230.1|6060906_6061509_+|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|379883
CP032698.1|AYG83223.1|6055133_6056066_-|putative-isomerase-YddE	unknown	unknown	gnl|CDD|334973
CP032698.1|AYG83231.1|6061652_6062390_+|hypothetical-protein	unknown	unknown	gnl|CDD|378140
CP032698.1|AYG83241.1|6071682_6072420_+|hypothetical-protein	unknown	unknown	gnl|CDD|273873
CP032698.1|AYG83233.1|6063696_6064671_-|Ferrous-iron-permease-EfeU	unknown	unknown	gnl|CDD|251822
CP032698.1|AYG83238.1|6069191_6069422_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83224.1|6056251_6057013_-|putative-oxidoreductase	unknown	unknown	gnl|CDD|212491
CP032698.1|AYG83234.1|6064680_6065943_-|putative-deferrochelatase/peroxidase-EfeN	unknown	unknown	gnl|CDD|273606

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83237.1|6068245_6069115_-|Methionine-aminopeptidase-2	gnl|CDD|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	7.56212e-146
CP032698.1|AYG83225.1|6057234_6058557_+|Bicyclomycin-resistance-protein	gnl|CDD|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	6.46597e-110
CP032698.1|AYG83236.1|6067436_6068099_-|Heme-oxygenase	gnl|CDD|350856	cd19165, HemeO, heme oxygenase in eukaryotes and some bacteria. This subfamily contains heme oxygenase (HO, EC 1.14.14.18) found in eukaryotes as well as some proteobacteria, including cyanobacteria. Heme oxygenase (HO) catalyzes the rate limiting step in the degradation of heme to biliverdin in a multi-step reaction. HO is essential for recycling of iron from heme which is used as a substrate and cofactor for its own degradation to biliverdin, iron, and carbon monoxide. In vertebrates, HO plays a role in heme homeostasis and oxidative stress response, and cellular signaling in mammals that include isoforms HO-1, HO-2 and HO-3. HO-1 is ubiquitously expressed after induction while HO-2 expression is constitutive, mostly limited to certain organs, such as the brain, testes, and the vascular system. HO-3 is non-functional in humans, suggesting that the Hmox3 gene is a pseudogene derived from HO-2 transcripts. In higher plants and cyanobacteria, heme oxygenase is required for the synthesis of light-harvesting pigments, which contain tetrapyrrols derived from biliverdin. Candida albicans expresses a heme oxygenase that is required for the utilization of heme as a nutritional iron source, whereas Saccharomyces cerevisiae responds to iron deprivation by increasing Hmx1p transcription, which is controlled by the major iron-dependent transcription factor, Aft1p, and promotes both the re-utilization of heme iron and the regulation of heme-dependent transcription during periods of iron scarcity. In pathogenic bacteria, HO is part of a pathway for iron acquisition from host heme. In Leptospira interrogans, a pathogenic spirochete that causes leptospirosis, HO is required for iron utilization when hemoglobin is the sole iron source, thus making HO an interesting target for novel antimicrobial agents. HO shares tertiary structure similarity to methane monooxygenase (EC 1.14.13.25), ribonucleotide reductase (EC 1.17.4.1) and thiaminase II (EC 3.5.99.2), but shares little sequence homology.	7.7055e-82
CP032698.1|AYG83230.1|6060906_6061509_+|putative-HTH-type-transcriptional-regulator	gnl|CDD|379883	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal. This family of bacterial transcriptional repressors is characterized by the short approximately 50 amino acid stretch of residues constituting the helix-turn-helix DNA binding motif, around the YRFhY motif. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. Another target protein is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	1.49528e-24
CP032698.1|AYG83239.1|6069607_6070906_-|Enterobactin-exporter-EntS	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.73869e-64
CP032698.1|AYG83228.1|6059586_6060369_-|hypothetical-protein	gnl|CDD|224747	COG1834, COG1834, N-Dimethylarginine dimethylaminohydrolase [Amino acid transport and metabolism].	9.21481e-62
CP032698.1|AYG83227.1|6059106_6059586_+|hypothetical-protein	gnl|CDD|286344	pfam09243, Rsm22, Mitochondrial small ribosomal subunit Rsm22. Rsm22 has been identified as a mitochondrial small ribosomal subunit and is a methyltransferase. In Schizosaccharomyces pombe, Rsm22 is tandemly fused to Cox11 (a factor required for copper insertion into cytochrome oxidase) and the two proteins are proteolytically cleaved after import into the mitochondria.	7.046e-77
CP032698.1|AYG83235.1|6065968_6067114_-|Efem/EfeO-family-lipoprotein	gnl|CDD|225378	COG2822, COG2822, Predicted periplasmic lipoprotein involved in iron transport [Inorganic ion transport and metabolism].	4.71357e-93
CP032698.1|AYG83231.1|6061652_6062390_+|hypothetical-protein	gnl|CDD|378140	pfam09250, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal. Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities.	8.27204e-21
CP032698.1|AYG83241.1|6071682_6072420_+|hypothetical-protein	gnl|CDD|273873	TIGR01915, F420-dependent_NADP_reductase, NADPH-dependent F420 reductase. This model represents a subset of a parent family described by pfam03807. Unlike the parent family, members of this family are found only in species with evidence of coenzyme F420. All members of this family are believed to act as NADPH-dependent F420 reductase. [Energy metabolism, Electron transport].	1.51148e-79
CP032698.1|AYG83233.1|6063696_6064671_-|Ferrous-iron-permease-EfeU	gnl|CDD|251822	pfam03239, FTR1, Iron permease FTR1 family.	7.29591e-69
CP032698.1|AYG83223.1|6055133_6056066_-|putative-isomerase-YddE	gnl|CDD|334973	pfam02567, PhzC-PhzF, Phenazine biosynthesis-like protein. PhzC/PhzF is involved in dimerization of two 2,3-dihydro-3-oxo-anthranilic acid molecules to create PCA by P. fluorescens. This family also contains uncharacterized Mycobacterial proteins, though there is no significant sequence similarity to pfam00303 members. This family appears to be distantly related to pfam01678, including containing a weak internal duplication. However members of this family do not contain the conserved cysteines that are hypothesized to be active site residues (Bateman A pers obs).	5.15355e-71
CP032698.1|AYG83224.1|6056251_6057013_-|putative-oxidoreductase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	9.57911e-60
CP032698.1|AYG83234.1|6064680_6065943_-|putative-deferrochelatase/peroxidase-EfeN	gnl|CDD|273606	TIGR01412, Probable_deferrochelatase/peroxidase_EfeN, Tat-translocated enzyme. This model represents a small family of proteins with a typical Tat (twin-arginine translocation) signal sequence, suggesting that the family is exported in a folded state, perhaps with a bound redox cofactor. Members of this family show homology to Dyp, a dye-decolorizing peroxidase from Geotrichum candidum that lacks any typical heme-binding site.	0

Protein sequences

>CP032698.1|AYG83231.1|6061652_6062390_+|hypothetical-protein
MGAEFGRSRGEESKLSRWLRRRPKDAPGVDPSRLSLLLAVAAADLPLAPAAYPIGYRCSCERMGCPTPARHPVSFAWQTQSTTDPAQIERWALGQPEANFITATGMVHDVLDVPLEAGREALARLLSEGIDVGPVAEAAGDGDNGRMLFFTATRGTPEDEDEWWPCELDCHPETMDEHPGLRWHCRGSYVLVPPARLPGELGVAWVRGPEHALPDPLTVLEALTDACARYAGETGAHAAAWPLGR
>CP032698.1|AYG83230.1|6060906_6061509_+|putative-HTH-type-transcriptional-regulator
MAETRTPDSTRRSERSRRAIYDAALSLVGEAGYGRTTIEGIAARAGVGKQTIYRWWPSKAEVLLEAFLERGGQAAESDPALPDTGDLEADLKQVLRATVDELTDPGFEIPYRALAAEGVINADLGAQFVRKLLEPGLQLYVDRLRAARDAGAIDPDVDPRVAVELLVGPLAHRWLLRTLPLTHAYADSLVEYALRGIAPR
>CP032698.1|AYG83229.1|6060563_6060722_-|hypothetical-protein
MLGVGGTRSRLSRQALRGTGGNARGGGGLDPMAQKRELLRKLKERRTASHEA
>CP032698.1|AYG83228.1|6059586_6060369_-|hypothetical-protein
MCPPAHFKVTYSINPWMDPEKPVDLPLALAQWEDLRDRYRALGHTVELLDPRPDLPDMVFAANGATVIDSRVLGARFAHPERAAEAAVHLAWFRAHGFTTVHEPSHINEGEGDFAVTASYLLAGRGFRSSPLSHDEAQEFFGRPVIGLDLVDPRYYHLDTALCVLDDAADEIMYYPAAFSPGSQAVLSRLFPHALIAEEPDAAALGLNAVSDGRHVLLPQGAIGLFDPLRARGYEPIGMDLGELLKGGGSVKCCTQELRS
>CP032698.1|AYG83227.1|6059106_6059586_+|hypothetical-protein
MDAAAAAATGAVVIVEPGTPDGYARIIEARDRLIAAGLHIAAPCPHSAACPIEPGTDWCHFSARVSRSSLHRQVKGGSLAYEDEKFSYLAATRFPPEPAAARVIRRPQIRKGQVLLELCTAQEQLRRETVSKRHGTLYRAARDAEWGDSWPPHPAEPAS
>CP032698.1|AYG83226.1|6058737_6058950_-|hypothetical-protein
MASAGSAQSRTVVATEVGTSCHASATAQLAEPVPPPMSVCVAGVHVPAASRNAPSAERTASNVAGIRYAA
>CP032698.1|AYG83225.1|6057234_6058557_+|Bicyclomycin-resistance-protein
MPERGGQDTQGPIPTTADARAPRAGAAVRRTSLLVTLVLGGLTALPPLSMDMYLPALPEVTDALRSPAATIQLTLTACLAGMALGQLVVGPMSDKWGRRRPLLIGMIVYVLATAVCAFAPNVELLISFRLLQGLAGAAGIVIARAVVRDLYDGVEMARFFSTLMLISGVAPVIAPLIGGQVLRLTDWRGVFAVLTVVGVLLTVVVFRWLHETLPVERRHSGGVKEALRTMGGLLKDRVFTGYMLAGGLAFAALFAYISASPFVVQEIYGASPQTFSLLFGLNSVGLVVVGQINGKLLIGRVSLDKVLGFGLAVIAVAATALLLMTSGVFGEVGLAPVAAGLFVLMSAMGLAMPNTNAQALMRTPNAAGSASALLGTSSFLVGAVASPLVGIAGEATAVPMAVVQLASAVAALLCFLLLCRPWQREHQSPSSASGGPAPQK
>CP032698.1|AYG83224.1|6056251_6057013_-|putative-oxidoreductase
MDITSQKAAVVTGAGSGIGRSVALVLAGAGWSVALAGRRAEALEETAALAGADPDVRCVPTDVTSPDEVGALFSATRAAYGRVDLLFNNAGAFGPIGVPVEDLSYEAWRSVVDVNLTGAFLCAQAAFRAMKEQTPQGGRIINNGSISAHTPRPRSVAYTATKHAMTGMTKSLSLDGRPYRIAVGQIDIGNAATEMTAPIQTGTLQANGELAVEPVMDAQDVARTVLHMAELPLEANIQFATVLATAMPYIGRG
>CP032698.1|AYG83223.1|6055133_6056066_-|putative-isomerase-YddE
MTSDAHPETLTHAGELPHPEALRHPEVLRYTAFTSDPAGGNPAGVVLDASGLGDAEMLAIAAELGYSESAFLTAPPQGLGEPGRAFTLRFFSPKAEVPFCGHATVATAVALGERIGPGELIFATPAGTVPVIVAEDLASGGLRATLTSVEPHSEPIGEKDLAEALAALDWRAEELDSAIPPRIAFAGARHLVLGAATRERLADLAYDFDRLTALMLRLDLTTVQLVWRASDSVFHVRDPFPVGGVVEDPATGAAAAAFGAYARELGLVDAESELTLHQGEDLGRPGVLTVTLRAGDSRVRVSGAGTRIAG
>CP032698.1|AYG83222.1|6054705_6055029_+|hypothetical-protein
MTIALDKLTDPAVRAFVGALNSGDREAFSAALTADATMSDDGADRDVADWTEREIFSSGGHMDIEKQTHDGLGLVANYRNDTWGEMRTSWRFTVDGGKVSRFETGQA
>CP032698.1|AYG83232.1|6062837_6063746_-|hypothetical-protein
MTVHGEREVVPSATRAEAARALTAFTDAYNKADKAYDPALDADRVTGAFGATTQAGFSARHVTSPGGNARYSPLELTGAAYTIPRQAGWPRWFVADTDSNRDQDDQGPGDTRWLLLFIRTGPQQGWKLAYLSILGVKDVPAFAKDKDGWAQPVRADDPSLALAPKDLSTSYASYLQSGKPPVFADGGHTSGWREARQKNAVRSGRVSQFVDQPLNEGDFAPLGLRTADGHALVFFAARHFERQTAAKGVRLEITPDEKAMLTGQVTTSLTREWISNELALVPAQGAVVVMDRVQGLVATKGE
>CP032698.1|AYG83233.1|6063696_6064671_-|Ferrous-iron-permease-EfeU
MFANYLIGLREGLEASLVVCILVAYLVKTGRRDALKPVWVGIAVAVLVAFAFGAGLEFGSQEMTFKAQEALGGSLSIIAVALVTWMVFWMRRTARHLKSELHGKLDSALRMGTGALVATAFLAVGREGLETALFVWTSVHAAGSENGTFQPMIGALLGLATAVFLGWLFYRGALKINLAKFFTWTGGMLVVVAAGVLAYGVHDLQEADFIAGINSKAFDISSTIAPDSWYGTLLKGVFNFQPDPTVLQVSVWALYLIPTLAFFFAPVGFRKSMGTKRVEGQKAVHEQGESADGGARDGDRTDGDRERLRDGARGAGSRTVGDEG
>CP032698.1|AYG83234.1|6064680_6065943_-|putative-deferrochelatase/peroxidase-EfeN
MSDTTEATEPARSPSRRALLGWGGAGLALGAAAAGGTVAVVKGGGSDAVPAAESGAAVPFHGAHQAGIATAVQDRLHFAAFDVTTKDRAALVQLLKDWTAAAAAMAEGKTVGEGAYGGLAEAPPDDTGEALGLKPSRLTLTFGVGPSLFAKDRFGLESKRPEALVDIEQFPGDNLDPARSGGDLCVQACADDPQVAVHAIRNLARIGMGKVAIRWSQLGFGKTSSTTPDAQTPRNMMGFKDGTRNVDGTDTKALDEHVWVGAKDGSDWMTGGSYLVARRIRMHIETWDRTSLQEQEDVFGRDKGEGAPVGKAKERDEPFLKAMKPTAHVRLAHPDSNDGARILRRGYSFTDGTDGLGRLDAGLFFLAYQRDVRKGFLPIQRALARQDALNEYIQHVGSAIFAVPPGVRDKGDWWGRGLFG
>CP032698.1|AYG83235.1|6065968_6067114_-|Efem/EfeO-family-lipoprotein
MRPVRTSVVTAAAAVAALTAVTGCADKSDAKADGAAGSIKVTATDSSCELSKNDFPAGHVKFDIENKGSKVTEVYLLFPDDRIVAERENIGPGLKQQLTAEVKAGSYEIACKPGMKGDGIRQKVTVTGGTAAKRNPALDTAVAEYRKYAQEQADETLPKVKVFTDAVRAGDLEAAKKAFAPSRLGWERTEPVAESFGDIDPKTDTREDGLEKGQKWTGWHRLEKSLWADGKIGQDEKDLATELDKDLADWQKRVGTAEITPTSMANGAKELLDEVATGKITGEEDRYSHTDLSDFKGNVEGAQKAYELLKPVAAKNDAALTTELDKQFGGLNTLLDKYRTDKTSYDFTSYDKVSEGDRKQLSDAVNALAEPLSKLAAAVTK
>CP032698.1|AYG83236.1|6067436_6068099_-|Heme-oxygenase
MTPSAPPPFSTLIRTASQQQHTEAESSTFMGDLLGGRLGVEAYARYTEQLWFVYRALEEGARALVDDPVAGPFIRPELMRTGALARDLAHLRGEGWRDTAVPLPATSAYADRVTQCARSWPAGYVAHHYTRYLGDLSGGQIIRDRAERTWGFTRRGDGVRFYVFEEIPNPAAFKRSYRELLDGVRVDEVERRRVVEECGRAFALNTAVFRELGEEFPLSA
>CP032698.1|AYG83237.1|6068245_6069115_-|Methionine-aminopeptidase-2
MSGQPKSQSLLVPGEISPARSVPGRIPRPEYVGKPMPAPYTGPEVQTPETIELMRTAGRIAAQAMEEAAKHIAPGVTTDELDRVAHEFMCDHGAYPSTLGYRGFPKSLCSSVNEVICHGIPDSTVLKDGDIVNLDVTAYIGGVHGDNNATYLCGDVDEESRLLVERTREALERAIKAVRPGRQINIIGRVIESYAKRFGYGVVRDFTGHGISTAFHSGLIVPHYDAPHATTVIKPGMTFTIEPMLTLGTHEYDMWEDGWTVVTKDRRRTAQFEHTLVVTETGTEILTLP
>CP032698.1|AYG83238.1|6069191_6069422_+|hypothetical-protein
MALFKKRTVGKPGEWFYCLAHHKVEEGPECPAKDRFGPYPTREEAEHAMRHAQERNLEWENDPKWHDKSAPTESAD
>CP032698.1|AYG83239.1|6069607_6070906_-|Enterobactin-exporter-EntS
MPEEPAASRLRSILPDLAPWRASADFRLLWVQGLITTFGSFMAMVALPLQIKELTDSPLAVGAMGAVELVPLVVFGLYGGALADAVDRRKVILATEAGLGLLALILLVNAVLPSPVLWPLYVVAAGVSALSGLQRPALDSLLARIVPHDHLPAAAALNAVRWQLGAIAGPSLAGLVVAYAGTATAYATTIGTFTVSVVMCARLSPAPPAHDARKPSLRGIAEGARYAWSRPVLLGTYAVDLAAMFFAFPNAIFPFLAESLHADWSLGLMYAAGSAGSVLLSLTSGWTSRVRRHGLFVVCGAAVWGTAMAGAGLLGNVWLVLACLAVAGAGDMLSGLGRSTIWNQTIPEELRGRLAGIEVLSYSVGPQLGQVRAGAMAGWTGTRAAVWSGGVACVATVGLLAAALPKLVTYDAATDEDAARRRAATQPTTTAV
>CP032698.1|AYG83240.1|6070984_6071587_-|hypothetical-protein
MDAVRVALLREVLAGTEWLRATRRFAGVLRSSVVPHGGGLLLVGTESYEPWHLAAHLTDEAAWSGLPELSPTLVRHRTEPGGPPHLSVGLGRLEAARRGETLLVVAPERPAEGLLSRVHDARRAGATVLALDGGDREVRGLVHECLTVAPDAELDLDTVQHLVSAAAGENTLPPQRGPRRFRDRLGRLADQLTAPPPGRW
>CP032698.1|AYG83241.1|6071682_6072420_+|hypothetical-protein
MTSTDNAGNASHDNAGTASKPAAKDPWELPDVSGLVVGVLGGTGDQGRGLAYRFARAGQKVIIGSRAAERARTAAEELGLGVEGADNAECARRSDIVIVAVPWDGHAKTLESLREELAGKLVVDCVNPLGFDKQGAYALKPQEGSAAQQAAALLPEARVTAAFHHLSAVLLQDASIEEIDTDVMVLGESRADTDVVQALAARIPGMRGVFAGRLRGAHQVESLVANLISMNRRYKAHAGLRVTDV

Crispr_ID: CP032698_84

• CRISPR_ID: CP032698_84
• CRISPR_location: 6088594-6088692
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_84

Consensus_repeat	Method
CCCCTGGGGCTCCGCCCCAGACCCCG	CRISPRCasFinder

spacers of CP032698_84

>84.1|6088620|47|CP032698|CRISPRCasFinder
GGCACCTCGCCCACCCACCCGCCCGTGCAGCGGGTTGAAGGGTTCGG

CRISPR arrays and Neighbor proteins around CP032698_84

CRISPR arrays

The CRISPR arrays of CP032698_84

>merge|CP032698|84|6088594-6088692|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCGGGCACCTCGCCCACCCACCCGCCCGTGCAGCGGGTTGAAGGGTTCGGCCCCTGGGGCTCCGCCCCAGACCCCG

>CP032698|84|61|6088594-6088692|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCG	GGCACCTCGCCCACCCACCCGCCCGTGCAGCGGGTTGAAGGGTTCGG
CCCCTGGGGCTCCGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83247.1|6079062_6079941_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234723
CP032698.1|AYG83251.1|6083667_6085419_-|Glutamine-dependent-NAD(+)-synthetase	unknown	unknown	gnl|CDD|237577
CP032698.1|AYG83264.1|6099525_6099981_-|hypothetical-protein	unknown	unknown	gnl|CDD|368286
CP032698.1|AYG83258.1|6093109_6094471_+|Glutamine-synthetase-2	unknown	unknown	gnl|CDD|223252
CP032698.1|AYG83249.1|6081796_6082426_+|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|379883
CP032698.1|AYG83256.1|6091260_6091902_-|hypothetical-protein	unknown	unknown	gnl|CDD|367619
CP032698.1|AYG83250.1|6082608_6083631_+|hypothetical-protein	unknown	unknown	gnl|CDD|197318
CP032698.1|AYG83255.1|6089128_6091087_-|Pseudomonalisin	unknown	unknown	gnl|CDD|173788
CP032698.1|AYG83254.1|6087715_6088537_+|Putative-aminoacrylate-hydrolase-RutD	unknown	unknown	gnl|CDD|223669
CP032698.1|AYG83253.1|6087041_6087719_+|hypothetical-protein	unknown	unknown	gnl|CDD|377627
CP032698.1|AYG83261.1|6098075_6098966_-|hypothetical-protein	unknown	unknown	gnl|CDD|214927
CP032698.1|AYG83248.1|6080136_6081744_+|Antiseptic-resistance-protein	unknown	unknown	gnl|CDD|184957
CP032698.1|AYG83262.1|6099051_6099324_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83257.1|6091898_6092615_-|hypothetical-protein	unknown	unknown	gnl|CDD|378632
CP032698.1|AYG83245.1|6076986_6077838_-|Daunorubicin/doxorubicin-resistance-ABC-transporter-permease-protein-DrrB	unknown	unknown	gnl|CDD|366444
CP032698.1|AYG83260.1|6095901_6098070_-|hypothetical-protein	unknown	unknown	gnl|CDD|378935
CP032698.1|AYG83263.1|6099344_6099503_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83246.1|6077834_6078872_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	unknown	unknown	gnl|CDD|130256
CP032698.1|AYG83252.1|6085576_6087028_+|Glutamate/gamma-aminobutyrate-antiporter	unknown	unknown	gnl|CDD|163525
CP032698.1|AYG83259.1|6094549_6095815_-|Putative-prophage-phiRv2-integrase	unknown	unknown	gnl|CDD|271189

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83247.1|6079062_6079941_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase	gnl|CDD|234723	PRK00311, panB, 3-methyl-2-oxobutanoate hydroxymethyltransferase; Reviewed.	2.93232e-157
CP032698.1|AYG83251.1|6083667_6085419_-|Glutamine-dependent-NAD(+)-synthetase	gnl|CDD|237577	PRK13981, PRK13981, NAD synthetase; Provisional.	0
CP032698.1|AYG83264.1|6099525_6099981_-|hypothetical-protein	gnl|CDD|368286	pfam05104, Rib_recp_KP_reg, Ribosome receptor lysine/proline rich region. This highly conserved region is found towards the C-terminus of the transmembrane domain. The function is unclear.	0.00757424
CP032698.1|AYG83258.1|6093109_6094471_+|Glutamine-synthetase-2	gnl|CDD|223252	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism].	0
CP032698.1|AYG83249.1|6081796_6082426_+|putative-HTH-type-transcriptional-regulator	gnl|CDD|379883	pfam16859, TetR_C_11, Bacterial transcriptional repressor C-terminal. This family of bacterial transcriptional repressors is characterized by the short approximately 50 amino acid stretch of residues constituting the helix-turn-helix DNA binding motif, around the YRFhY motif. The target proteins that are repressed are involved in the transcriptional control of multi-drug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. Another target protein is BetI, an osmoprotectant which controls the choline-glycine betaine pathway in E.coli.	3.93639e-18
CP032698.1|AYG83256.1|6091260_6091902_-|hypothetical-protein	gnl|CDD|367619	pfam03713, DUF305, Domain of unknown function (DUF305). Domain found in small family of bacterial secreted proteins with no known function. Also found in Paramecium bursaria chlorella virus 1. This domain is short and found in one or two copies. The domain has a conserved HH motif that may be functionally important. This domain belongs to the ferritin superfamily. It contains two sequence similar repeats each of which is composed of two alpha helices.	7.38594e-50
CP032698.1|AYG83250.1|6082608_6083631_+|hypothetical-protein	gnl|CDD|197318	cd09084, EEP-2, Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2. This family of uncharacterized proteins belongs to a superfamily that includes the catalytic domain (exonuclease/endonuclease/phosphatase, EEP, domain) of a diverse set of proteins including the ExoIII family of apurinic/apyrimidinic (AP) endonucleases, inositol polyphosphate 5-phosphatases (INPP5), neutral sphingomyelinases (nSMases), deadenylases (such as the vertebrate circadian-clock regulated nocturnin), bacterial cytolethal distending toxin B (CdtB), deoxyribonuclease 1 (DNase1), the endonuclease domain of the non-LTR retrotransposon LINE-1, and related domains. These diverse enzymes share a common catalytic mechanism of cleaving phosphodiester bonds; their substrates range from nucleic acids to phospholipids and perhaps, proteins.	1.15502e-23
CP032698.1|AYG83255.1|6089128_6091087_-|Pseudomonalisin	gnl|CDD|173788	cd04056, Peptidases_S53, Peptidase domain in the S53 family. Members of the peptidases S53 (sedolisin) family include endopeptidases and exopeptidases sedolisin, kumamolysin, and (PSCP) Pepstatin-insensitive Carboxyl Proteinase. The S53 family contains a catalytic triad Glu/Asp/Ser with an additional acidic residue Asp in the oxyanion hole, similar to that of Asn in subtilisin. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values. Characterized sedolisins include Kumamolisin, an extracellular calcium-dependent thermostable endopeptidase from Bacillus. The enzyme is synthesized with a 188 amino acid N-terminal preprotein region which is cleaved after the extraction into the extracellular space with low pH. One kumamolysin paralog, kumamolisin-As, is believed to be a collagenase. TPP1 is a serine protease that functions as a tripeptidyl exopeptidase as well as an endopeptidase. Less is known about PSCP from Pseudomonas which is thought to be an aspartic proteinase.	8.86685e-72
CP032698.1|AYG83254.1|6087715_6088537_+|Putative-aminoacrylate-hydrolase-RutD	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	4.04211e-15
CP032698.1|AYG83253.1|6087041_6087719_+|hypothetical-protein	gnl|CDD|377627	pfam06197, DUF998, Protein of unknown function (DUF998). Family of conserved archaeal proteins.	1.16856e-08
CP032698.1|AYG83261.1|6098075_6098966_-|hypothetical-protein	gnl|CDD|214927	smart00943, Prim-Pol, Bifunctional DNA primase/polymerase, N-terminal. Members of this family adopt a structure consisting of a core of antiparallel beta sheets. They are found in various bacterial hypothetical proteins, and have been shown to harbour both primase and polymerase activities.	9.68922e-14
CP032698.1|AYG83248.1|6080136_6081744_+|Antiseptic-resistance-protein	gnl|CDD|184957	PRK14995, PRK14995, SmvA family efflux MFS transporter.	9.78631e-78
CP032698.1|AYG83257.1|6091898_6092615_-|hypothetical-protein	gnl|CDD|378632	pfam11303, DUF3105, Protein of unknown function (DUF3105). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	7.08676e-57
CP032698.1|AYG83245.1|6076986_6077838_-|Daunorubicin/doxorubicin-resistance-ABC-transporter-permease-protein-DrrB	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	5.59989e-19
CP032698.1|AYG83260.1|6095901_6098070_-|hypothetical-protein	gnl|CDD|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	8.79907e-09
CP032698.1|AYG83246.1|6077834_6078872_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	gnl|CDD|130256	TIGR01188, drrA, daunorubicin resistance ABC transporter ATP-binding subunit. This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other].	1.13307e-135
CP032698.1|AYG83252.1|6085576_6087028_+|Glutamate/gamma-aminobutyrate-antiporter	gnl|CDD|163525	TIGR03813, put_Glu_GABA_T, putative glutamate/gamma-aminobutyrate antiporter. Members of this protein family are putative putative glutamate/gamma-aminobutyrate antiporters. Each member of the seed alignment is found adjacent to a glutamate decarboxylase, which converts glutamate (Glu) to gamma-aminobutyrate (GABA). However, the majority belong to genome contexts with a glutaminase (converts Gln to Glu) as well as the decarboxylase that converts Glu to GABA. The specificity of the transporter remains uncertain.	3.86256e-112
CP032698.1|AYG83259.1|6094549_6095815_-|Putative-prophage-phiRv2-integrase	gnl|CDD|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.36131e-24

Protein sequences

>CP032698.1|AYG83254.1|6087715_6088537_+|Putative-aminoacrylate-hydrolase-RutD
MRPVGRFLRWGGVAHHVVVEGAGPVVVLSAGLGMSWFDWDPVMPLLAPHHTVVRFDRPGHGLSGPAVAPPTAAGEAGRIAGLLDGLGLPGPVTVVGHSIAGFHAEAFARLHPSRTAGLLLVDSSVEERARPPAALPARLALARAAGSLLGHAGAPAALGPAARRAVVRASRTGGGDPAPRDLVRLCYRGGRVWRGLLLENATYGSVAAELLCLRRELELPACPATVLAGGAGGPRWVRRQRGLAGVLGARFAVAEGAGHLLMLDAPGSLAGLL
>CP032698.1|AYG83253.1|6087041_6087719_+|hypothetical-protein
MSRSGVRPRPVAALLALGALAYTAWVLELVFHTGLDPIQAYVSELAAADQPFGGLFRATDLGAGLLVLAGAVCALARCDRRRWPLLGWFGLALFGAATALDSRLPLSCAPTADPVCAARETAGLVPATHTAHAVSSSLAMVGALLGVLALTVAARRYGWWPPLAALGPALVALELAATAWTLTSVAAFQAGRGTWALGAGQRLQVLLVAIWLGVLAWSVAKESRK
>CP032698.1|AYG83252.1|6085576_6087028_+|Glutamate/gamma-aminobutyrate-antiporter
MTTTDASDEELVADEGTPRQLVSWVTLGLMTTASVASLRPSPSMAIYGLAAIFLYLLPAVVFLLPTALVGAELASGWTGGIYRWVSEALGKPLGFLAVWCQFAMTIAYYPSLLAYVASTFAYVIDPSLAENGLYVAIVIVVIYWTGVWISSRGTKTVAGLSSMGLVIGTLVPGVVLVALGFVFLGQGNPSAAPMNASHWLPPWTGLASLVLIVNNFLSYAGMEMNGVHVSSLRDPKREYPKSMFLATGLVLLIFILPALAISWVMPSSQLSLTAGLMQAFQAFFDHFHIGWMTKVVGVMLVAAALGGMLTWLAGPAKGLVLLSRQEGYLPPFLQRLNRYGTPQNIMVAQGVITTLIGILYAFSGDVSSAYWMFSVITVQIYLIAYLLMFVAVVRLRRTRPEVERGFRVPAVAWVAGIGFVASVAALFIGFVPPDQFGGQPLWRYLLIVGGGLLALGVLAPLAFLKFRKPSWVHPDHQRPLPPP
>CP032698.1|AYG83251.1|6083667_6085419_-|Glutamine-dependent-NAD(+)-synthetase
MPQLRLALNQIDSTVGDIPGNTEAIVHWTRHCAEQGAHLVAFPEMMLTGYPVEDLALRSSFVEASRRALTALAARLAAEGFGEIPVVVGHLDRSPVAVPRLGQPAGAPQNAAAVLHGGRVVLGFAKHHLPNYGVFDEFRYFVPGDTMPVVRVRGVDVALAICEDLWQDGGRVPATRSAGAGLLISINASPYEQNKDDSRLDLVRKRAQQAGCTLAYVATVGGQDELVFDGDSIVVDASGHVLARAPQFSEGAVILDLELPAAGPAPSGVVDDGLRIDHAVISEEPVPAYEPELTGGYAERLDDDEEVYSALVVGLRAYVAKNGFRSVLIGLSGGIDSALVAAIACDALGAANVHGVSMPSKYSSDHSRSDAAELARRTGLALRTVPVEPMFDAYMGSLDLTGLAEENLQSRLRGTMLMALSNQEGHLVLAPGNKSELAVGYSTLYGDSVGAYGPIKDVYKSAVFRLARWRNRAAAERGQTPPIPENSISKPPSAELRPGQVDTDSLPDYPVLDAILAMYVDQDQGADAIVAAGYEPELVTKTLRMVDTAEYKRRQYPPGTKISPKGFGKDRRLPITNQWRESS
>CP032698.1|AYG83250.1|6082608_6083631_+|hypothetical-protein
MARAYMTETGDGSAEGERTGSRFRRLTDRWRNDRGIWRRGLVLAGFAVLIALVMVLHARIPNSIGNLGSLSETFLPWLGVFLPVLLGLALWRRSATALIALLLPVIMWFNMFGGLLTDKQGSGGDLVVATHNVNADNKDPAGTARQVAASGAQVLALEEIPGDQVTTYKKALADRYPYHSVQGTVGLWSTYPLSDSRPVDIKMGWTRAMRSTVRTPSGDVAVYVAHMPSVRVKLNAGFTANQRDNSAYTLGEAISAEPLGKVVLLGDLNGTMNDRSLNNITAQMRSTQGAAGSGFGFTWPAGFPMARIDQIMVKGLQPTSSWTLARTGSDHLPIAARLKV
>CP032698.1|AYG83249.1|6081796_6082426_+|putative-HTH-type-transcriptional-regulator
MTLMDKRHRDDGDGEPRRGRPRSEAVERQILEAVIVLLEEGVPFADLSIERIARTAGVGKATIYRRWAGKEELFVEVVRSMESPTPPLPGHSLRDDLIAVVDNVRRRGAAKRSSALLHNVFAQMQSYPKLWSKYHSLVIDPRRELLDELLRRGVANGELRAGLDLDMTGDLFVAPMLVRTMMRPDTELPGPELAERIVDAVLEGLRPPR
>CP032698.1|AYG83248.1|6080136_6081744_+|Antiseptic-resistance-protein
MSTTSPASGAPAAPRIPEAVHRRRWAILAVLMLSLLIVVLDNSILNVAVKTIASPAPTGLGATQSELEWAINAYTLVFAGLLFTSGLLGDRLGRKKILLFGITVFGLGSVLAAFSNSPDQLIAFRALMGLGGAFVMPATLAVLMNVFEREEQPKAIGIWAGGVGLAIAIGPITGGVLLQHFWWGSVFLVNVPVVIIALIAMVVLVPDSRDPNPGKLDPVGVLLSVVGLVLLVYGIIHGGELADFTDPTVLATILGGVAVLVGFVLYEKRCDHPAIDIGYFKKPAFSAAVVAIALTFFALMGVTFFSVFYMQSVRGYSALESGLLILPLAAAQMIFAPRARLVVDRFGARAVCTAGLVLVAVGLAAFGLFDATTPIWVMEVVFFLQGAGMAHIMPPVTVSIMQALPREKAGSGSAVNNTFRQVGGALGVAVLGSLLSTVYRGDIEGHLGAVPEGARKAAGESIEATLGIAERMGPEGKALIGPANDAFIHAMHITAFASAGVALLGALVVLLFLPGKPPAGPSPQAQDRPTEAARR
>CP032698.1|AYG83247.1|6079062_6079941_-|3-methyl-2-oxobutanoate-hydroxymethyltransferase
MTQQLPSAQIPKASDSSDPKALYGGKGTRRITVHDIAAAKARGEKWPMLTAYDAMTASVFDEAGIPVLLVGDSMGNCHLGYETTVPVTLDEITMLSAAVVRGTSRALVVGDLPFGSYQEGPVQALRTAMRLVKDAGVGAVKLEGGERSHEQIRLLVDSGIPVMGHIGLTPQSVNTLGYRVQGRGDEAAHQLLRDAKAVQDAGAFAVVLELVPAELAAEVTRILHIPTVGIGAGAECDAQVLVYTDMVGLTPGKTPRFTKQYMDLRASLGEAAKAFAGEVVGGAFPAEEHTFH
>CP032698.1|AYG83246.1|6077834_6078872_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA
MTRIDKNPTGGAEAVAAGTAISVRGLVKHFGSTKALDGVDLDVREGTVLGVLGPNGAGKTTLVRCLSTLLVPDAGTATVAGYDVVRQPRQLRRTIGLTGQYASVDEKLSGRENLYMIGRLLDLSRKEARSRADELLERFSLTDAAKRPAMTYSGGMRRRLDLAASMIGHPAVLYLDEPTTGLDPRTRNEVWDEVRRMVAEGATVLLTTQYMEEAEQLASELTVIDRGTVIANGEVDELKARVGGRTLQIRPTDPQQLGSMARAVTEAGLDGVSGTQVVPDEGVLNVPILSDQQLTAVVALLGSRGYGIAHIGTHLPSLDEVFLAITGQKTADSQDAHRETEEVAA
>CP032698.1|AYG83245.1|6076986_6077838_-|Daunorubicin/doxorubicin-resistance-ABC-transporter-permease-protein-DrrB
MSTTTVEAPAQQSPSAAPRPTGSDDVRIGLRANLRHIGALARRNMLQIKADPESMFDAVLMPIIFILLFVYVFGGAMFGDGNQGAYVNYLVPGLMAMMGLNIAMAVGTGVNDDFKKGVMDRFRTMPIARSSVLIAKMVVEVGRMMVATTILLIMGFILGLSISTSVWGLLAAVGLSLTFGASLMWIFILLGLTMKTAQAVQGVAMLVLMPLQFGSSIFAKPTTMPGWLQSFTDYNPLSNLADAARGLMIGGPVAHSALMTLAWSAGITVVMAPLAVAKFRKRT
>CP032698.1|AYG83255.1|6089128_6091087_-|Pseudomonalisin
MRISRARRRAGVSMAATLPLLAGALALGIPSAQAADPVPGGRAALAGTQPTWATGSADQGAASASTKVDARVYLAGRDAKGLDAYAAAVSDPRSPSYGKYLSTAQAQQRFGATQEQIDAVTQWLKSSGLTVTGSNQHYISVSGDVAAAQKAFATQLHNYRKGNRTYRAPAKNASAPNALAGAVLTVTGLDNAPHKATHQDTLPGPGAGFRNAGPFSTYYGSNVAKTLPDAYGGKVPYAVHGYTGQQLRAAYGAGEYTGKGVTVAITDAYASPTMASDAAQYAKRNGDKPYKTGQYTEVLPADYNSTEACDASGWYGEESLDVEAVHAVAPDANIVYVGGASCNDPDLLDALNKVVDRHLADIVSNSWGDIEANETPDVAAAYDQTFKLGAIEGIGFYFSSGDNGDEVANTGKKQVDTPANSAWVTAVGGTSLAVGKNDKYQFETGWGTEKASLSADGKSWVNFPGAYTSGAGGGTSSTVKQPFYQRHVVPDALAKANGATRMRTVPDIAAVADPNTGFLVGQTQSWPDKSVKYDEYRIGGTSLAAPVIAGVQALAQQAQRSPIGFANPSIYARFDSRLYHDVTDHPLGAARDLAVARVDFANSVDASGGLLTSVRSLGKDSSLVATRGYDDVTGVGSPAPGYVASYTNPFRR
>CP032698.1|AYG83256.1|6091260_6091902_-|hypothetical-protein
MSRRSWGLTAALALAMVFAAAAVLVSSGGNGSAAEAKPRTPEATSADAGFARDMATHHQQAVEMSFIVRDRTSDEEVRRLAYDIANTQANQRGMMLGWLDLWGLPKNEASQAPMAWMGMAMEPGADGALMPGMATNADLNRLRGLGGRDAEVLYLQLMTEHHKGGIHMAEGCVRRCTVGPEKRLAQGMVDSQHSEIDLMAQMLRKRGVTPKTN
>CP032698.1|AYG83257.1|6091898_6092615_-|hypothetical-protein
MTMQDDYHASRRAHIEEQQRNRQARRRRETIVAISSVTAAVLVVAGLVGFGVYKFSTMKDSGSTSAAPRTEPSARGSGDASGQGSGDAGAPIAGEKDWDTKKLTRNHVTTPVRYPMTPPVGGDHAAVWMNCGGVVYQKPVPDVNAVHSLEHGAVWVTYTDKASAADVKKLGGKVSVTPYSLMSPYQDQAGAIMLSAWGKQLTVDSADDPRVNQFFTRYVEGPQTPEPGAPCTGGLDER
>CP032698.1|AYG83258.1|6093109_6094471_+|Glutamine-synthetase-2
MDKQQEFVLRTLEERDIRFVRLWFTDVLGFLKSVAVAPAELEQAFDEGIGFDGSAIEGFARVYESDMIARPDPSTFQILPWRAEAPGTARMFCDIRMPDGSPSFADPRFVLKRILAKTSDLGFTFYTHPEIEFFLLKDKPLDGTRPVPADNSGYFDHTPQNVGMDFRRQAITMLESMGISVEFSHHEGAPGQQEIDLRYADALSTADNIMTFRLVMKQVALEQGVQATFMPKPFSEYPGSGMHTHLSLFEGDRNAFYESGAEYQLSKVGRSFIAGLLKHAAEIAAVTNQWVNSYKRIWGGSERTAGAGGEAPSYICWGHNNRSALIRVPMYKPGKTGSSRIEVRSLDSGCNPYLAYALLLAAGLKGIEEGYELPAGADDDVWALTDAERRAMGIEPLPQNLGEAITLMERSELVAETLGEHVFDFFLRNKKQEWEEYRSEVTAFELRKNLPVL
>CP032698.1|AYG83259.1|6094549_6095815_-|Putative-prophage-phiRv2-integrase
MAGHIQDRWYKTETNSVGKTVRTRTDRYGSGLRYRARYIGPDGTEKAKSFPDGQKRLAEQWLTKIKADMDGGRYIDPKAGRTTFRQYAEKWLNSQTTDPTTREPVGVQIRRHAIPYLGSRPLGTFKPEHIRDWLAELERSVPASSYRRVIFASVSGVFTAAVEDDHLHRNPCKASTVHAPGPNNRRVVPWTAERTFAVRAALPEQYRAAVDLGAGCGLRQGEIFGLPVDEIGFDTGWLHVGCQVKVSGGKLVFGLPKRNKERDVPLADSVAHALKKHMDTYPPVEVTLPWQRPDGPPVTKRLLFVRPDGGGAVRRTDFNTRYWKSALVTAGVIPEPKPGERHQAAREHGMHALRHFYASVLLDAGENIKALSSYLGHTDPGFTLRVYTHLLPSSEGRSRNAVDAVFHPAASASDGPQTAQP
>CP032698.1|AYG83260.1|6095901_6098070_-|hypothetical-protein
MSEDEKDPARKVITEYAQSHFRYFRTTEGTVYAQRNGHPVARPIRSQGTTGSHRQELMVDLFRDGLGVFNGTAMKEALDLIEALALSQDVQPTHIRVAPGFDGATWLDLGRDDGQSVRIHPTGWEITVPDPREVSWRRTQLTGELPLPATDTDGKGIDLLLGLCNFAGPATECLAIAWLLGCLEPSVPVPAPFLTGPQGAGKSTGGRMLVRILEGMTGDLRRAPKDEENLITAVAAGWVTALDNLSHLPPDLSDLMCCIVTGAESIKRALFTDGDVVRSRYRRPLLLTGIDVGVIRPDLAERLLPLRLERPRVRRTEAELWADYAEALPVVLGSMLDLAVKVRAADAVTPTDLRMADFAHLCAQFDAVAGLGTLDAYRASLDDLNDDVIEGDLLAQTVLKHATELDPGVDVRMTSAEWLHCLTSLYSGEECRPLPKGWPTTGKVLSDRLKRLQPTLAARGVLVDWGRNKTARYIEMSRQAPPPPPSNKPRSDRLPGGRTSKRSTPGRVLLLLVPAAQPLGKGRAAKRPRIHALSSDAPPQKPPLLFSKKGRPASPASPRPRTRPLTCHNSGDADGRILRHRASPASSVRHPMTDACVTGDADPEPLRHPKPQVNGSGDADDAMTQKSPLRTAQPTTPAKAPPRRHRMRPPPVIDTLRNGIPDRYLTPEDIAAIFEVPKETVYQWRKKRVGPPGFRIGKHVRYDPAEVLTYVAERKNADRDAA
>CP032698.1|AYG83261.1|6098075_6098966_-|hypothetical-protein
MTQPTDIRRERTQGPSCPSMCDLVTTALEVARTGLPVLPLRQGKVPFGNCRTCANNACGGRPNMKNAGPCQCPDVCHAWAAATTDPNVISSPAWGRAWRRAVSVAYHPGGAGLTVVDLDTPAAVAWARDILPPTRTVPTTRGEHWLYQGAMRSVNGVRAGVDIKSTMAYARWRGHGTGTLTALPDTVRALVAKSAPALRPQVVAVAALAGGGECPHRTPAFLERGIAMAEERISEARSTVHTTVYRTFLAVLSTHGRCGCLTDAHVARLFAAAQAKGESARHCADAWANARTALGM
>CP032698.1|AYG83262.1|6099051_6099324_-|hypothetical-protein
MLRLRLQLTGWSRRTLILTDTPRPDCPDCEGDGAIGCDYGDHEGEYADTDWYPCGCWTQWRKALMPLPRLPRLLRRRVDHRDPWSDEPPF
>CP032698.1|AYG83263.1|6099344_6099503_-|hypothetical-protein
MAHTPARPPKRYPGAASTTPGGRVHLGSRPDTAPRGSEYLDTTRNDPRTRAS
>CP032698.1|AYG83264.1|6099525_6099981_-|hypothetical-protein
MFPEHPRHAPVERVIEVHHPAPIQPVAAPLVPVQPGTVPAVASIVLPDGRVVTGYAIAPAKPEPIAAKPAVSRTAVNVALGGIGFAAVCGGLLLLTSFIAALTAFITQLIILAAVIFGGWISVQVLGPRHGDGGTVVNIRRAVFKRNHFHG

Crispr_ID: CP032698_86

• CRISPR_ID: CP032698_86
• CRISPR_location: 6253445-6253545
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_86

Consensus_repeat	Method
CGGGGTCTGGGGCGGAGCCCCAGG	CRISPRCasFinder

spacers of CP032698_86

>86.1|6253469|53|CP032698|CRISPRCasFinder
AGGCCCGGAACCATCCAACCCCCGTCACGGGCGGGTGGGTGGGCAAGGCGCCT

CRISPR arrays and Neighbor proteins around CP032698_86

CRISPR arrays

The CRISPR arrays of CP032698_86

>merge|CP032698|86|6253445-6253545|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGGAGGCCCGGAACCATCCAACCCCCGTCACGGGCGGGTGGGTGGGCAAGGCGCCTCGGGGTCTGGGGCGGAGCCCCAGG

>CP032698|86|62|6253445-6253545|CRISPRCasFinder
CGGGGTCTGGGGCGGAGCCCCAGG	AGGCCCGGAACCATCCAACCCCCGTCACGGGCGGGTGGGTGGGCAAGGCGCCT
CGGGGTCTGGGGCGGAGCCCCAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83392.1|6243440_6244802_+|Chromosome-partition-protein-Smc	unknown	unknown	gnl|CDD|377585
CP032698.1|AYG83406.1|6259871_6260621_+|hypothetical-protein	unknown	unknown	gnl|CDD|226098
CP032698.1|AYG83394.1|6246341_6247370_+|putative-endopeptidase	unknown	unknown	gnl|CDD|366353
CP032698.1|AYG83390.1|6242232_6242982_-|hypothetical-protein	unknown	unknown	gnl|CDD|223777
CP032698.1|AYG83407.1|6260914_6261274_+|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG83402.1|6256545_6257025_+|hypothetical-protein	unknown	unknown	gnl|CDD|176861
CP032698.1|AYG83401.1|6255657_6256419_+|hypothetical-protein	unknown	unknown	gnl|CDD|277338
CP032698.1|AYG83393.1|6245076_6246102_+|putative-endopeptidase	unknown	unknown	gnl|CDD|366353
CP032698.1|AYG83409.1|6262049_6262652_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83408.1|6261225_6261723_+|hypothetical-protein	unknown	unknown	gnl|CDD|376573
CP032698.1|AYG83396.1|6248640_6249168_-|hypothetical-protein	unknown	unknown	gnl|CDD|224609
CP032698.1|AYG83399.1|6251932_6253075_+|GDP-mannose-dependent-alpha-(1-6)-phosphatidylinositol-monomannoside-mannosyltransferase	unknown	unknown	gnl|CDD|340831
CP032698.1|AYG83397.1|6249257_6250586_+|putative-FMN/FAD-exporter-YeeO	unknown	unknown	gnl|CDD|240542
CP032698.1|AYG83400.1|6253585_6255382_-|Long-chain-fatty-acid--CoA-ligase-FadD15	unknown	unknown	gnl|CDD|341233
CP032698.1|AYG83395.1|6247449_6248619_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83398.1|6250546_6251815_-|hypothetical-protein	unknown	unknown	gnl|CDD|378217
CP032698.1|AYG83404.1|6258227_6258704_+|hypothetical-protein	unknown	unknown	gnl|CDD|375065
CP032698.1|AYG83391.1|6243139_6243394_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83405.1|6258833_6259787_+|Glucokinase	unknown	unknown	gnl|CDD|273246
CP032698.1|AYG83403.1|6257027_6258158_+|hypothetical-protein	unknown	unknown	gnl|CDD|223082

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83392.1|6243440_6244802_+|Chromosome-partition-protein-Smc	gnl|CDD|377585	pfam05991, NYN_YacP, YacP-like NYN domain. This family consists of bacterial proteins related to YacP. This family is uncharacterized functionally, but it has been suggested that these proteins are nucleases due to them containing a NYN domain. NYN (for N4BP1, YacP-like Nuclease) domains were discovered by Anantharaman and Aravind. Based on gene neighborhoods it was suggested that the bacterial YacP proteins interact with the Ribonuclease III and TrmH methylase in a processome complex that catalyzes the maturation of rRNA and tRNA.	1.26189e-12
CP032698.1|AYG83408.1|6261225_6261723_+|hypothetical-protein	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.86597e-11
CP032698.1|AYG83394.1|6246341_6247370_+|putative-endopeptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	5.40738e-31
CP032698.1|AYG83390.1|6242232_6242982_-|hypothetical-protein	gnl|CDD|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	1.3431e-28
CP032698.1|AYG83407.1|6260914_6261274_+|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.67438e-21
CP032698.1|AYG83402.1|6256545_6257025_+|hypothetical-protein	gnl|CDD|176861	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	2.39157e-53
CP032698.1|AYG83393.1|6245076_6246102_+|putative-endopeptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	6.23544e-27
CP032698.1|AYG83401.1|6255657_6256419_+|hypothetical-protein	gnl|CDD|277338	cd07392, MPP_PAE1087, Pyrobaculum aerophilum PAE1087 and related proteins, metallophosphatase domain. PAE1087 is an uncharacterized Pyrobaculum aerophilum protein with a metallophosphatase domain. The domain present in members of this family belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	7.88368e-15
CP032698.1|AYG83399.1|6251932_6253075_+|GDP-mannose-dependent-alpha-(1-6)-phosphatidylinositol-monomannoside-mannosyltransferase	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.85955e-67
CP032698.1|AYG83406.1|6259871_6260621_+|hypothetical-protein	gnl|CDD|226098	COG3568, ElsH, Metal-dependent hydrolase [General function prediction only].	2.78306e-18
CP032698.1|AYG83400.1|6253585_6255382_-|Long-chain-fatty-acid--CoA-ligase-FadD15	gnl|CDD|341233	cd05907, VL_LC_FACS_like, Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases. This family includes long-chain fatty acid (C12-C20) CoA synthetases and Bubblegum-like very long-chain (>C20) fatty acid CoA synthetases. FACS catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, and the formation of a fatty acyl-CoA. Eukaryotes generally have multiple isoforms of LC-FACS genes with multiple splice variants. For example, nine genes are found in Arabidopsis and six genes are expressed in mammalian cells. Drosophila melanogaster mutant bubblegum (BGM) have elevated levels of very-long-chain fatty acids (VLCFA) caused by a defective gene later named bubblegum. The human homolog (hsBG) of bubblegum has been characterized as a very long chain fatty acid CoA synthetase that functions specifically in the brain; hsBG may play a central role in brain VLCFA metabolism and myelinogenesis. Free fatty acids must be "activated" to their CoA thioesters before participating in most catabolic and anabolic reactions.	0
CP032698.1|AYG83396.1|6248640_6249168_-|hypothetical-protein	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	4.74121e-17
CP032698.1|AYG83398.1|6250546_6251815_-|hypothetical-protein	gnl|CDD|378217	pfam09594, GT87, Glycosyltransferase family 87. The enzymes in this family are glycosyltransferases. PimE is involved in phosphatidylinositol mannoside (PIM) synthesis, a major class of glycolipids in all mycobacteria. PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of PIM. The family also includes alpha(1-->3) arabinofuranosyltransferase, invloved in the synthesis of of mycobacterial arabinogalactan.	0.000242982
CP032698.1|AYG83404.1|6258227_6258704_+|hypothetical-protein	gnl|CDD|375065	pfam17230, DUF5304, Family of unknown function (DUF5304). This family of unknown function is found in Actinobacteria.	4.24461e-56
CP032698.1|AYG83397.1|6249257_6250586_+|putative-FMN/FAD-exporter-YeeO	gnl|CDD|240542	cd13137, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	7.03524e-67
CP032698.1|AYG83405.1|6258833_6259787_+|Glucokinase	gnl|CDD|273246	TIGR00744, Glucokinase_Glucose_kinase., ROK family protein (putative glucokinase). This model models one branch of the ROK superfamily of proteins. The three members of the seed alignment for this model all have experimental evidence for activity as glucokinase, but the set of related proteins is crowded with paralogs of different or unknown function. Proteins scoring above the trusted_cutoff will show strong similarity to at least one known glucokinase and may be designated as putative glucokinases. However, definitive identification of glucokinases should be done only with extreme caution. [Unknown function, General].	1.39505e-159
CP032698.1|AYG83403.1|6257027_6258158_+|hypothetical-protein	gnl|CDD|223082	COG0003, ArsA, Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning].	2.27681e-35

Protein sequences

>CP032698.1|AYG83399.1|6251932_6253075_+|GDP-mannose-dependent-alpha-(1-6)-phosphatidylinositol-monomannoside-mannosyltransferase
MHKTLIVTNDFPPRPGGIQAFLHNMALRLDPEQVVVYASTWKRGQEGAAATAAFDAEQPFTVVRDRTTMLLPTPRVTRRAVGLLREHGCSSVWFGAAAPLGLMGPALRRAGAERLVATTHGHEAGWAQLPVARQLLRRIGEGTDTITYLGEYTRSRIAGALTPQAAARMVQLPPGVDEKTFHPGSGGDAVRERLGLTDRPVVVCVSRLVPRKGQDTLILALPAILAQVPDAVLLIVGGGPYEAELRKLAADTGVASSVRFTGAVPWAELPAHYGAGDVFAMPCRTRRGGLDVEGLGIVYLEASATGLPVVAGDSGGAPDAVLDGETGFVVRGGSPEDSAARIVTLLQDAGLRGRMGERGRAWVEERWRWDLLARKLRGLL
>CP032698.1|AYG83398.1|6250546_6251815_-|hypothetical-protein
MAAPGPRNEDETDIMSIPRRPLAVAATWAVTRFLLLLCAFRVLLLPGPDVTSDVHAIYQGWSQVLATGTYPLDDVTWQYPPAAALAILSPAALPFLDYATAFFALVFLADAVVFCLLMYAADRPGRSLNGAWVWTLGVALLGPTAYARYDLMVTAVAVAALLAGVGRPRVLGALAAFGALLKGWPALLLIRAPRRAWTAAAVSAAALLTACVAAAPGAFAFLTFQRERGTEVESLGALVFHLARLFGWRGTVQLNYGSVEFLGPYVPLVSALSMALTVLAFGWLLLWRVRAGGPMRPSTPADAAFTAVLLFTTTSRVISPQYMLWLVGLAAVCLVHRRGPMARPARLVLAATGVTFLEFPIWFSHVVAGDWLGLLLLTVRNGLLVWASLLACRILWRTTVSPRTPSVLSPQPARAGEPSTTR
>CP032698.1|AYG83397.1|6249257_6250586_+|putative-FMN/FAD-exporter-YeeO
MEATAHRRRLVSLAFPVYGELMAGVAAGIINTLWVTRLGGDAVAAVAVATNVENVLLGIALMAGSGTTVLLARARGAGEQGAVRAAVRGGWALWALLAPAVAIGAFLGREPIARLVLGADAGGALPLAVGYFSIALPGIAVFFATNVVDGILKGTGDTRTPMRLALLSNGLILVLDPLLILGCGLGVRGAALATVAGRSVALARGLLVLRRTPALRAAGPVPHAWTTDLRRTVRTGLPLSADFVTRMGGALAVVAVVARIGVAEVAAYGIATKAMYGATMAFYSVRQAAAIHTARLLGAGRDERGAVGREVLRVAAVLGAGAGLVLFAAAPWIMAAFGAHGAVATAGVLQLRCLGPYLMLLACFIGWGGVVEGGGGSPRLVRITGCGVALQLVLAHALSGLGLPGICLAMALAMGVQCAALARLHRRTGAQRVVDGSPARAG
>CP032698.1|AYG83396.1|6248640_6249168_-|hypothetical-protein
MLELSILGFLYEEPLHGYELKERIKGLSGHIRPVSDGALYPAITRLVKAGVLEQRTEPGSGAAPRRTLSLTDAGRAALLERLRHPKDVEITDGQRFFTLLAFLRHLPDPAEQAAVLARRQAFLQAPASFFYRDGEPVTVERAPDPFRQGMLRIARATGREEKAWLAETIEELGGG
>CP032698.1|AYG83395.1|6247449_6248619_+|hypothetical-protein
MLLCATACSAPAAAPDATTGEVQQVLDRRAAAVLKHDASGYLAALDPAASALRASQGAEFTNLAQVPLASWAYRVTGVDHKGPQATAQVELRYRIQGYDTAPVTAARTLTLGRRGGTWYVTGDLPARGAAQPLWQQGPVTVVRGARSLILGVGQDAAKLRGIAAAEDAAVPAVSAAWPGVWARRVVVLVPASLDGMAALLGAPAASYRGIAAVTTGEVGGAGAAPADRVIVNPDAYAVLGDLGRRVVLAHETTHVATRAHTSPATPLWLSEGYADWIGYRDTGRTAPQAAPELLKAVRAGDLPADLPSDADFGFDGGADRLAKAYESGWLACRMIAANWGEAALARFYTEVGDQPHREGALEKAMDDQLGLNLREFTTRWREYVRSQLA
>CP032698.1|AYG83394.1|6246341_6247370_+|putative-endopeptidase
MASHRRPSQSGLTQSARVTVLSAAAATAAAALGATVASAAPQEPSPSGQAAVDRLFEEAERATEQFDKADEHAKLLRDQVKQAQDGVARGQEKINRMRGALGAIAGAQYRSGGIDPALALLLSSNPATYLDQAATLDRLGERQSGALQDLRHEQRHLAQQRAEASRKLAELERSRTDVARHKRTVESKLAEARRVLNALPSADRAAFDRASRSERGELPPLSDSAPASSRAAAAVMAARSAIGKPYIWGANGPSGFDCSGLMQWSYARAGVGLPRTSQAQRYAGRQVPLSEAKPGDLVAYRHDASHIAMYVGNGQVVHAPYPGAPVRYDPVGMMPVSSVTRV
>CP032698.1|AYG83393.1|6245076_6246102_+|putative-endopeptidase
MGSHRRPKPASRTRVTVLSATAAAVVALTSQAAQADPKPTKDEVKSKVDKLYDEAEQATEAANGAKEKQGQLEKQIGEIQDKVARGQQELNTLRSGLGSMASAQYRSGGIDPSLALFLSSNPDDFLDKASSLDQLSANQTEALQKIQGKQRTLAQQRKEAQDKLKDLADTRQVLDDKKKEVQGKLGEAQKLLNTLTAQEKAALASDEARANRSTERPNLGKDVPASGVGAAALAAAQGQLGKPYSYGTTGMATFDCSGLTGYAYGQAGVHLPRTSQEQATRGTRIGRGDLKPGDLVLFFGDLHHIGLYAGNNTVLHAPHSGAVVRYESMDNMPFQFGVRIG
>CP032698.1|AYG83392.1|6243440_6244802_+|Chromosome-partition-protein-Smc
MEHASGAEPAAAAGDGPAEVLDRPLPEGVRRRVVAFVSEAFGGLTVAELPAQLRQYARFTPTRRAKFAGNAMAAALEGDPVFRQRIGERLKESQPELAGAVEAGSPPAAADPVDVAAAAYVLRPAGWVKLVAAAGEEAQRAFAERAEEEGRREVERLREELAEARERIRSENETLRAELLAARKEAETLQRKLRSAQSDVKRGEAALRRTTAEIDGIKSEAAARVTAAESETRRLKTRLSEAESGLEASRRATREGRSVEDMRLRLLLDTVLEGAQGLRRELALPPASVRPADTVDAVAPGTMTPKDIAARALSETDPALLDQLLALPQVHLLVDGYNVTKTGYPTMPLEKQRLRLLGGLSVLAAQTGAEVTCVFDGAELAAPVLLAPPRGVRVLFSKPGVTADELIRQLVRAEPSGRPVVVASTDKEVADGVAKAGARPVASLLLLKRLSRV
>CP032698.1|AYG83391.1|6243139_6243394_+|hypothetical-protein
MSTVPRMTAETRWRCSLCGNLTRFDVTRSSKVVEYVHLDLAGEPTVEEREVVSETIESVRCRWCNAVDQIELVDRPGTDTATAS
>CP032698.1|AYG83390.1|6242232_6242982_-|hypothetical-protein
MTKRRATAILSGAVHGPTVTYGLIAACCLLFLVSPVSGLNPVYGTGDAILSAQSDHFARWGVIPAELMAGRPHALLTPLTALFVHGSWLHLLGNMLFLYVFGAMAEERLGWPEFALFYLVSGYLALFAYAAAHAGSQQTLVGASGAISAVLGAFLYLFPRARVTSIFPFLLFLPLRFPAWIVLIFWFALQWLAIQGASAGPGVAYLAHLVGFGLGFLYAWARFGGADRVKRRKPVKTAGPAATEGESQP
>CP032698.1|AYG83400.1|6253585_6255382_-|Long-chain-fatty-acid--CoA-ligase-FadD15
MREFSLPALYEVPSDGNLTDLIRRNAAQHPDVAVMGRKIAGAWADVTARQFLAEVRAVAKGLIAAGVEAGDRVALLSRTRYEWVLIDFAIWSAGAVTVPVYETSSPEQIQWILGDSAATLAIVESPAHEASVESVRAGLPALKGIWQVEADAVARLAATGADVPDAVLDARMSSAHADDPATIVYTSGTTGRPKGCVLTHRAFFAECGNVVERLKPLFRTGECSVLLFLPVAHVFGRLVEVASVMAPIKLGCVPDIKNLTDELASFRPTLILGVPRVFEKVYNSARAKAQADGKGKIFDKAAGTAIAYSKALSTDAGPSIGLKLKHKVFDKLVYSKLRAVLGGRGEYAISGGAPLGERLGHFFRGIGFTVLEGYGLTESCAATAFNPWDRPKIGTVGQPLPGSVVRIADDGEVLLHGEHLFQSYWNNESATAEALADGWFHTGDIGTLDEDGYLAITGRKKEIIVTAGGKNVAPAVIEDRIRGHALVAECMVVGDGRPFVGALITLDEEFLGRWAEEHGKPVGATAISLRDDAELLAEVQRAVDDGNAAVSKAESVRKFRILGAQFTEEAGHITPSLKLKRNVVAKDFADEIEAIYTP
>CP032698.1|AYG83401.1|6255657_6256419_+|hypothetical-protein
MRVHVVSDVHGNAEGLAKAGEGADALICLGDLVLFLDYADHSRGIFPDLFGVDNADRIVALRTARRFEEARELGRSLWAGLDREAAIEAAVRRQYAELFAAFPTPTYATYGNVDLPHLWPQYAGPGTTVLDGQRVEIAGRVFGFVGGGLRTPMRTPHEISDEEYAAKVEALGEVDVLCSHIPPEVPELVYDTVARRFERGSRALLAAIEKTRPRYSLFGHVHQPLARRMRIGRTECVNVGHFAATSRPFALQW
>CP032698.1|AYG83402.1|6256545_6257025_+|hypothetical-protein
MAEHTSSSITIEATPADVMGVIADFARYPEWTGEVKEAEVLATDAAGHAEKVRLLLDAGAIKDDHTLAYTWNGNTVSWTLVKSQMLRTLDGSYILADAPGGRTEVTYRLTVDVKIPMLGMIKRKAEKVIIDRALAGLKKRVESGSGGAEAGSADGTKKL
>CP032698.1|AYG83403.1|6257027_6258158_+|hypothetical-protein
MRTVLVTGPGGAGRTTVAAATARAAARRGTRVTLLTADRLPGELAGVTVRRIDAAAHFRAELLAFQDRAGAALDLLGASRLDAEELTELPGAEQLALLAALREAAADEPGLLVVDLPPADRALATLALPEQLRRYLRRLLPPERQAARSLRPVLAQLAGVPMPAQWLYETAARWDRELAAVQAVIEDAGTTVRLVAEPGPAAAEALGTARLGIAVHGLALDAVVANRLLPAETPDPWLAGLVAQQRKHLDELAGEFPAVREVAHLGRDPRGDDDLDLLDAAYGPDESVPPPPRWSVRDRLAEDDVLVWSLPLPGAVKDGLSLVRRGDELLLTVGPFRRIVPLPSALRRCTVTGAGLHDGVLDIRFAPDPELWPRGQ
>CP032698.1|AYG83404.1|6258227_6258704_+|hypothetical-protein
MSEATERPAPDADAWADACAEDLAAEQERRRAQYGPEPGSAAEELRKLLGAVTDKFAGLFDGPSGLSGMAAQGAVQQLISQAKAAVEPVIERNPEVFDHLAAAGGELLAAYRSAVEGHEKRWTSDAGRTGPGGKGTGPDGTGRDGDQGPGPTEHIDLD
>CP032698.1|AYG83405.1|6258833_6259787_+|Glucokinase
MGLTIGVDIGGTKIAAGVVDEEGNILSTHKVPTPGTPDAIVDAIASAVDGARVGHEIVGVGIGAAGYVNRQRSTVYFAPNIDWRQEPLKEKVELRVGLPVVVENDANAAAWGEYRFGAGKGHRNVICITLGTGLGGGIIIGNKLRRGHFGVAAEFGHIRMVPDGLLCGCGSQGCWEQYASGRALVRYAKQRANATPERAEFLLGLGDGTPEGIEGKHISMAARQGDPVAVDSYRELARWAGAGLADLASLFDPSAFIVGGGLSDEGELVLDPIRKSYKRWLVGGNWRPVADVIAAQLGNKAGLVGAADLARQPDPIM
>CP032698.1|AYG83406.1|6259871_6260621_+|hypothetical-protein
MTTPDGGLPASATESGSAVIRVLSYNIRSMRDDNAALARVIRACAPDLVLIQEAPRFFRWRKAAARLAAATDLVILGGGATAAGPMLLCSLRATVEQTEDVLLPLTPGLHRRGFATAVVRIGGARIGVLSAHLSLQEAERYEQTGALLDRLAGMGVDHAIAGGDLNERPDGRGFRRLAGALQDCWEVAPWGGEFTSTPADPHQRIDAIFATAGVEVLGCGVPLGLAAPADLRTATDHLPVLAALRVPGA
>CP032698.1|AYG83407.1|6260914_6261274_+|hypothetical-protein
MVGIVERLVPDELWELFQRVVPEAPSRPQGGGRRRHGDREVLAAIVFVATSGCTWQQLPSASFGPSGATAHRRFSEWSKARVWAKLHRLVLDELGARGELDWSRCAIDSVNMRALKRGT
>CP032698.1|AYG83408.1|6261225_6261723_+|hypothetical-protein
MRDRLGEHAGPEKGDLTGPNPVDRGKYGSKIHLITERSGLPISVGISGANLHDSQALIPLVKGIPPIRSRRGPRRRKPSKLHADKGYDYAHLRQWLRERGITHRIARKGVESSQRLGRHRWTVERTMAWLAGCRRLHRRYERKADHFLAFTSIACTLICYRRLAK
>CP032698.1|AYG83409.1|6262049_6262652_-|hypothetical-protein
MAEHDADREPQPIDEEAAWAAIVAGYGEEPADPPGTRPFRSVEDLALIEDETAEEGEGPDPAVKTKGPGKGLDKPALGSSVVFAPGVGGPRDFTPADPAGDGAGAPDPSDPSDPSDPSDEGHFVPPEPPPLPEADAAAKFAWLGVIGGPLLLILAAIFGWDMTWWLTTLGVGGFLGGIATLFARMQPDEDDDDPGRGAVV

Crispr_ID: CP032698_85

• CRISPR_ID: CP032698_85
• CRISPR_location: 6253115-6253370
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP032698_85

Consensus_repeat	Method
TCGCGCAGTTCCCCGCGCCCCTNAA	CRT

spacers of CP032698_85

>85.1|6253140|33|CP032698|CRT
ACCCGTCTGCGTCTGCGGGCCACGGGCGGCTGC
>85.2|6253198|31|CP032698|CRT
CCCTCTCGACCCTGCGGACCGTGCCCGCGTC
>85.3|6253254|36|CP032698|CRT
AAAACCCGCTTTCGTCTGCGGGCCGTGGCTGGCTGG
>85.4|6253315|31|CP032698|CRT
AGCCCTTCGGTCTGCGGACCGTGCTCGCTTC

CRISPR arrays and Neighbor proteins around CP032698_85

CRISPR arrays

The CRISPR arrays of CP032698_85

>merge|CP032698|85|6253115-6253370|CRT
TTGCGCAGTTCCCCGCGCCCCTGAAACCCGTCTGCGTCTGCGGGCCACGGGCGGCTGCTCGCGCAGTTCCCCGCGCCCCTAAACCCTCTCGACCCTGCGGACCGTGCCCGCGTCTCGCGCAGTTCCCCGCGCCCCCAAGAAAACCCGCTTTCGTCTGCGGGCCGTGGCTGGCTGGTCGCGCAGTTCCCCGCGCCCCTAAAAGCCCTTCGGTCTGCGGACCGTGCTCGCTTCTCGCGCAGTTCCTCGCGCCCCTTAA

>CP032698|85|10|6253115-6253370|CRT
TTGCGCAGTTCCCCGCGCCCCTGAA	ACCCGTCTGCGTCTGCGGGCCACGGGCGGCTGC
TCGCGCAGTTCCCCGCGCCCCTAAA	CCCTCTCGACCCTGCGGACCGTGCCCGCGTC
TCGCGCAGTTCCCCGCGCCCCCAAG	AAAACCCGCTTTCGTCTGCGGGCCGTGGCTGGCTGG
TCGCGCAGTTCCCCGCGCCCCTAAA	AGCCCTTCGGTCTGCGGACCGTGCTCGCTTC
TCGCGCAGTTCCTCGCGCCCCTTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83392.1|6243440_6244802_+|Chromosome-partition-protein-Smc	unknown	unknown	gnl|CDD|377585
CP032698.1|AYG83406.1|6259871_6260621_+|hypothetical-protein	unknown	unknown	gnl|CDD|226098
CP032698.1|AYG83394.1|6246341_6247370_+|putative-endopeptidase	unknown	unknown	gnl|CDD|366353
CP032698.1|AYG83390.1|6242232_6242982_-|hypothetical-protein	unknown	unknown	gnl|CDD|223777
CP032698.1|AYG83407.1|6260914_6261274_+|hypothetical-protein	unknown	unknown	gnl|CDD|379129
CP032698.1|AYG83402.1|6256545_6257025_+|hypothetical-protein	unknown	unknown	gnl|CDD|176861
CP032698.1|AYG83401.1|6255657_6256419_+|hypothetical-protein	unknown	unknown	gnl|CDD|277338
CP032698.1|AYG83393.1|6245076_6246102_+|putative-endopeptidase	unknown	unknown	gnl|CDD|366353
CP032698.1|AYG83409.1|6262049_6262652_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83408.1|6261225_6261723_+|hypothetical-protein	unknown	unknown	gnl|CDD|376573
CP032698.1|AYG83396.1|6248640_6249168_-|hypothetical-protein	unknown	unknown	gnl|CDD|224609
CP032698.1|AYG83399.1|6251932_6253075_+|GDP-mannose-dependent-alpha-(1-6)-phosphatidylinositol-monomannoside-mannosyltransferase	unknown	unknown	gnl|CDD|340831
CP032698.1|AYG83397.1|6249257_6250586_+|putative-FMN/FAD-exporter-YeeO	unknown	unknown	gnl|CDD|240542
CP032698.1|AYG83400.1|6253585_6255382_-|Long-chain-fatty-acid--CoA-ligase-FadD15	unknown	unknown	gnl|CDD|341233
CP032698.1|AYG83395.1|6247449_6248619_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83398.1|6250546_6251815_-|hypothetical-protein	unknown	unknown	gnl|CDD|378217
CP032698.1|AYG83404.1|6258227_6258704_+|hypothetical-protein	unknown	unknown	gnl|CDD|375065
CP032698.1|AYG83391.1|6243139_6243394_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83405.1|6258833_6259787_+|Glucokinase	unknown	unknown	gnl|CDD|273246
CP032698.1|AYG83403.1|6257027_6258158_+|hypothetical-protein	unknown	unknown	gnl|CDD|223082

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83392.1|6243440_6244802_+|Chromosome-partition-protein-Smc	gnl|CDD|377585	pfam05991, NYN_YacP, YacP-like NYN domain. This family consists of bacterial proteins related to YacP. This family is uncharacterized functionally, but it has been suggested that these proteins are nucleases due to them containing a NYN domain. NYN (for N4BP1, YacP-like Nuclease) domains were discovered by Anantharaman and Aravind. Based on gene neighborhoods it was suggested that the bacterial YacP proteins interact with the Ribonuclease III and TrmH methylase in a processome complex that catalyzes the maturation of rRNA and tRNA.	1.26189e-12
CP032698.1|AYG83408.1|6261225_6261723_+|hypothetical-protein	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	1.86597e-11
CP032698.1|AYG83394.1|6246341_6247370_+|putative-endopeptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	5.40738e-31
CP032698.1|AYG83390.1|6242232_6242982_-|hypothetical-protein	gnl|CDD|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	1.3431e-28
CP032698.1|AYG83407.1|6260914_6261274_+|hypothetical-protein	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	7.67438e-21
CP032698.1|AYG83402.1|6256545_6257025_+|hypothetical-protein	gnl|CDD|176861	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	2.39157e-53
CP032698.1|AYG83393.1|6245076_6246102_+|putative-endopeptidase	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	6.23544e-27
CP032698.1|AYG83401.1|6255657_6256419_+|hypothetical-protein	gnl|CDD|277338	cd07392, MPP_PAE1087, Pyrobaculum aerophilum PAE1087 and related proteins, metallophosphatase domain. PAE1087 is an uncharacterized Pyrobaculum aerophilum protein with a metallophosphatase domain. The domain present in members of this family belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	7.88368e-15
CP032698.1|AYG83399.1|6251932_6253075_+|GDP-mannose-dependent-alpha-(1-6)-phosphatidylinositol-monomannoside-mannosyltransferase	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.85955e-67
CP032698.1|AYG83406.1|6259871_6260621_+|hypothetical-protein	gnl|CDD|226098	COG3568, ElsH, Metal-dependent hydrolase [General function prediction only].	2.78306e-18
CP032698.1|AYG83400.1|6253585_6255382_-|Long-chain-fatty-acid--CoA-ligase-FadD15	gnl|CDD|341233	cd05907, VL_LC_FACS_like, Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases. This family includes long-chain fatty acid (C12-C20) CoA synthetases and Bubblegum-like very long-chain (>C20) fatty acid CoA synthetases. FACS catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, and the formation of a fatty acyl-CoA. Eukaryotes generally have multiple isoforms of LC-FACS genes with multiple splice variants. For example, nine genes are found in Arabidopsis and six genes are expressed in mammalian cells. Drosophila melanogaster mutant bubblegum (BGM) have elevated levels of very-long-chain fatty acids (VLCFA) caused by a defective gene later named bubblegum. The human homolog (hsBG) of bubblegum has been characterized as a very long chain fatty acid CoA synthetase that functions specifically in the brain; hsBG may play a central role in brain VLCFA metabolism and myelinogenesis. Free fatty acids must be "activated" to their CoA thioesters before participating in most catabolic and anabolic reactions.	0
CP032698.1|AYG83396.1|6248640_6249168_-|hypothetical-protein	gnl|CDD|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	4.74121e-17
CP032698.1|AYG83398.1|6250546_6251815_-|hypothetical-protein	gnl|CDD|378217	pfam09594, GT87, Glycosyltransferase family 87. The enzymes in this family are glycosyltransferases. PimE is involved in phosphatidylinositol mannoside (PIM) synthesis, a major class of glycolipids in all mycobacteria. PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of PIM. The family also includes alpha(1-->3) arabinofuranosyltransferase, invloved in the synthesis of of mycobacterial arabinogalactan.	0.000242982
CP032698.1|AYG83404.1|6258227_6258704_+|hypothetical-protein	gnl|CDD|375065	pfam17230, DUF5304, Family of unknown function (DUF5304). This family of unknown function is found in Actinobacteria.	4.24461e-56
CP032698.1|AYG83397.1|6249257_6250586_+|putative-FMN/FAD-exporter-YeeO	gnl|CDD|240542	cd13137, MATE_NorM_like, Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	7.03524e-67
CP032698.1|AYG83405.1|6258833_6259787_+|Glucokinase	gnl|CDD|273246	TIGR00744, Glucokinase_Glucose_kinase., ROK family protein (putative glucokinase). This model models one branch of the ROK superfamily of proteins. The three members of the seed alignment for this model all have experimental evidence for activity as glucokinase, but the set of related proteins is crowded with paralogs of different or unknown function. Proteins scoring above the trusted_cutoff will show strong similarity to at least one known glucokinase and may be designated as putative glucokinases. However, definitive identification of glucokinases should be done only with extreme caution. [Unknown function, General].	1.39505e-159
CP032698.1|AYG83403.1|6257027_6258158_+|hypothetical-protein	gnl|CDD|223082	COG0003, ArsA, Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning].	2.27681e-35

Protein sequences

>CP032698.1|AYG83399.1|6251932_6253075_+|GDP-mannose-dependent-alpha-(1-6)-phosphatidylinositol-monomannoside-mannosyltransferase
MHKTLIVTNDFPPRPGGIQAFLHNMALRLDPEQVVVYASTWKRGQEGAAATAAFDAEQPFTVVRDRTTMLLPTPRVTRRAVGLLREHGCSSVWFGAAAPLGLMGPALRRAGAERLVATTHGHEAGWAQLPVARQLLRRIGEGTDTITYLGEYTRSRIAGALTPQAAARMVQLPPGVDEKTFHPGSGGDAVRERLGLTDRPVVVCVSRLVPRKGQDTLILALPAILAQVPDAVLLIVGGGPYEAELRKLAADTGVASSVRFTGAVPWAELPAHYGAGDVFAMPCRTRRGGLDVEGLGIVYLEASATGLPVVAGDSGGAPDAVLDGETGFVVRGGSPEDSAARIVTLLQDAGLRGRMGERGRAWVEERWRWDLLARKLRGLL
>CP032698.1|AYG83398.1|6250546_6251815_-|hypothetical-protein
MAAPGPRNEDETDIMSIPRRPLAVAATWAVTRFLLLLCAFRVLLLPGPDVTSDVHAIYQGWSQVLATGTYPLDDVTWQYPPAAALAILSPAALPFLDYATAFFALVFLADAVVFCLLMYAADRPGRSLNGAWVWTLGVALLGPTAYARYDLMVTAVAVAALLAGVGRPRVLGALAAFGALLKGWPALLLIRAPRRAWTAAAVSAAALLTACVAAAPGAFAFLTFQRERGTEVESLGALVFHLARLFGWRGTVQLNYGSVEFLGPYVPLVSALSMALTVLAFGWLLLWRVRAGGPMRPSTPADAAFTAVLLFTTTSRVISPQYMLWLVGLAAVCLVHRRGPMARPARLVLAATGVTFLEFPIWFSHVVAGDWLGLLLLTVRNGLLVWASLLACRILWRTTVSPRTPSVLSPQPARAGEPSTTR
>CP032698.1|AYG83397.1|6249257_6250586_+|putative-FMN/FAD-exporter-YeeO
MEATAHRRRLVSLAFPVYGELMAGVAAGIINTLWVTRLGGDAVAAVAVATNVENVLLGIALMAGSGTTVLLARARGAGEQGAVRAAVRGGWALWALLAPAVAIGAFLGREPIARLVLGADAGGALPLAVGYFSIALPGIAVFFATNVVDGILKGTGDTRTPMRLALLSNGLILVLDPLLILGCGLGVRGAALATVAGRSVALARGLLVLRRTPALRAAGPVPHAWTTDLRRTVRTGLPLSADFVTRMGGALAVVAVVARIGVAEVAAYGIATKAMYGATMAFYSVRQAAAIHTARLLGAGRDERGAVGREVLRVAAVLGAGAGLVLFAAAPWIMAAFGAHGAVATAGVLQLRCLGPYLMLLACFIGWGGVVEGGGGSPRLVRITGCGVALQLVLAHALSGLGLPGICLAMALAMGVQCAALARLHRRTGAQRVVDGSPARAG
>CP032698.1|AYG83396.1|6248640_6249168_-|hypothetical-protein
MLELSILGFLYEEPLHGYELKERIKGLSGHIRPVSDGALYPAITRLVKAGVLEQRTEPGSGAAPRRTLSLTDAGRAALLERLRHPKDVEITDGQRFFTLLAFLRHLPDPAEQAAVLARRQAFLQAPASFFYRDGEPVTVERAPDPFRQGMLRIARATGREEKAWLAETIEELGGG
>CP032698.1|AYG83395.1|6247449_6248619_+|hypothetical-protein
MLLCATACSAPAAAPDATTGEVQQVLDRRAAAVLKHDASGYLAALDPAASALRASQGAEFTNLAQVPLASWAYRVTGVDHKGPQATAQVELRYRIQGYDTAPVTAARTLTLGRRGGTWYVTGDLPARGAAQPLWQQGPVTVVRGARSLILGVGQDAAKLRGIAAAEDAAVPAVSAAWPGVWARRVVVLVPASLDGMAALLGAPAASYRGIAAVTTGEVGGAGAAPADRVIVNPDAYAVLGDLGRRVVLAHETTHVATRAHTSPATPLWLSEGYADWIGYRDTGRTAPQAAPELLKAVRAGDLPADLPSDADFGFDGGADRLAKAYESGWLACRMIAANWGEAALARFYTEVGDQPHREGALEKAMDDQLGLNLREFTTRWREYVRSQLA
>CP032698.1|AYG83394.1|6246341_6247370_+|putative-endopeptidase
MASHRRPSQSGLTQSARVTVLSAAAATAAAALGATVASAAPQEPSPSGQAAVDRLFEEAERATEQFDKADEHAKLLRDQVKQAQDGVARGQEKINRMRGALGAIAGAQYRSGGIDPALALLLSSNPATYLDQAATLDRLGERQSGALQDLRHEQRHLAQQRAEASRKLAELERSRTDVARHKRTVESKLAEARRVLNALPSADRAAFDRASRSERGELPPLSDSAPASSRAAAAVMAARSAIGKPYIWGANGPSGFDCSGLMQWSYARAGVGLPRTSQAQRYAGRQVPLSEAKPGDLVAYRHDASHIAMYVGNGQVVHAPYPGAPVRYDPVGMMPVSSVTRV
>CP032698.1|AYG83393.1|6245076_6246102_+|putative-endopeptidase
MGSHRRPKPASRTRVTVLSATAAAVVALTSQAAQADPKPTKDEVKSKVDKLYDEAEQATEAANGAKEKQGQLEKQIGEIQDKVARGQQELNTLRSGLGSMASAQYRSGGIDPSLALFLSSNPDDFLDKASSLDQLSANQTEALQKIQGKQRTLAQQRKEAQDKLKDLADTRQVLDDKKKEVQGKLGEAQKLLNTLTAQEKAALASDEARANRSTERPNLGKDVPASGVGAAALAAAQGQLGKPYSYGTTGMATFDCSGLTGYAYGQAGVHLPRTSQEQATRGTRIGRGDLKPGDLVLFFGDLHHIGLYAGNNTVLHAPHSGAVVRYESMDNMPFQFGVRIG
>CP032698.1|AYG83392.1|6243440_6244802_+|Chromosome-partition-protein-Smc
MEHASGAEPAAAAGDGPAEVLDRPLPEGVRRRVVAFVSEAFGGLTVAELPAQLRQYARFTPTRRAKFAGNAMAAALEGDPVFRQRIGERLKESQPELAGAVEAGSPPAAADPVDVAAAAYVLRPAGWVKLVAAAGEEAQRAFAERAEEEGRREVERLREELAEARERIRSENETLRAELLAARKEAETLQRKLRSAQSDVKRGEAALRRTTAEIDGIKSEAAARVTAAESETRRLKTRLSEAESGLEASRRATREGRSVEDMRLRLLLDTVLEGAQGLRRELALPPASVRPADTVDAVAPGTMTPKDIAARALSETDPALLDQLLALPQVHLLVDGYNVTKTGYPTMPLEKQRLRLLGGLSVLAAQTGAEVTCVFDGAELAAPVLLAPPRGVRVLFSKPGVTADELIRQLVRAEPSGRPVVVASTDKEVADGVAKAGARPVASLLLLKRLSRV
>CP032698.1|AYG83391.1|6243139_6243394_+|hypothetical-protein
MSTVPRMTAETRWRCSLCGNLTRFDVTRSSKVVEYVHLDLAGEPTVEEREVVSETIESVRCRWCNAVDQIELVDRPGTDTATAS
>CP032698.1|AYG83390.1|6242232_6242982_-|hypothetical-protein
MTKRRATAILSGAVHGPTVTYGLIAACCLLFLVSPVSGLNPVYGTGDAILSAQSDHFARWGVIPAELMAGRPHALLTPLTALFVHGSWLHLLGNMLFLYVFGAMAEERLGWPEFALFYLVSGYLALFAYAAAHAGSQQTLVGASGAISAVLGAFLYLFPRARVTSIFPFLLFLPLRFPAWIVLIFWFALQWLAIQGASAGPGVAYLAHLVGFGLGFLYAWARFGGADRVKRRKPVKTAGPAATEGESQP
>CP032698.1|AYG83400.1|6253585_6255382_-|Long-chain-fatty-acid--CoA-ligase-FadD15
MREFSLPALYEVPSDGNLTDLIRRNAAQHPDVAVMGRKIAGAWADVTARQFLAEVRAVAKGLIAAGVEAGDRVALLSRTRYEWVLIDFAIWSAGAVTVPVYETSSPEQIQWILGDSAATLAIVESPAHEASVESVRAGLPALKGIWQVEADAVARLAATGADVPDAVLDARMSSAHADDPATIVYTSGTTGRPKGCVLTHRAFFAECGNVVERLKPLFRTGECSVLLFLPVAHVFGRLVEVASVMAPIKLGCVPDIKNLTDELASFRPTLILGVPRVFEKVYNSARAKAQADGKGKIFDKAAGTAIAYSKALSTDAGPSIGLKLKHKVFDKLVYSKLRAVLGGRGEYAISGGAPLGERLGHFFRGIGFTVLEGYGLTESCAATAFNPWDRPKIGTVGQPLPGSVVRIADDGEVLLHGEHLFQSYWNNESATAEALADGWFHTGDIGTLDEDGYLAITGRKKEIIVTAGGKNVAPAVIEDRIRGHALVAECMVVGDGRPFVGALITLDEEFLGRWAEEHGKPVGATAISLRDDAELLAEVQRAVDDGNAAVSKAESVRKFRILGAQFTEEAGHITPSLKLKRNVVAKDFADEIEAIYTP
>CP032698.1|AYG83401.1|6255657_6256419_+|hypothetical-protein
MRVHVVSDVHGNAEGLAKAGEGADALICLGDLVLFLDYADHSRGIFPDLFGVDNADRIVALRTARRFEEARELGRSLWAGLDREAAIEAAVRRQYAELFAAFPTPTYATYGNVDLPHLWPQYAGPGTTVLDGQRVEIAGRVFGFVGGGLRTPMRTPHEISDEEYAAKVEALGEVDVLCSHIPPEVPELVYDTVARRFERGSRALLAAIEKTRPRYSLFGHVHQPLARRMRIGRTECVNVGHFAATSRPFALQW
>CP032698.1|AYG83402.1|6256545_6257025_+|hypothetical-protein
MAEHTSSSITIEATPADVMGVIADFARYPEWTGEVKEAEVLATDAAGHAEKVRLLLDAGAIKDDHTLAYTWNGNTVSWTLVKSQMLRTLDGSYILADAPGGRTEVTYRLTVDVKIPMLGMIKRKAEKVIIDRALAGLKKRVESGSGGAEAGSADGTKKL
>CP032698.1|AYG83403.1|6257027_6258158_+|hypothetical-protein
MRTVLVTGPGGAGRTTVAAATARAAARRGTRVTLLTADRLPGELAGVTVRRIDAAAHFRAELLAFQDRAGAALDLLGASRLDAEELTELPGAEQLALLAALREAAADEPGLLVVDLPPADRALATLALPEQLRRYLRRLLPPERQAARSLRPVLAQLAGVPMPAQWLYETAARWDRELAAVQAVIEDAGTTVRLVAEPGPAAAEALGTARLGIAVHGLALDAVVANRLLPAETPDPWLAGLVAQQRKHLDELAGEFPAVREVAHLGRDPRGDDDLDLLDAAYGPDESVPPPPRWSVRDRLAEDDVLVWSLPLPGAVKDGLSLVRRGDELLLTVGPFRRIVPLPSALRRCTVTGAGLHDGVLDIRFAPDPELWPRGQ
>CP032698.1|AYG83404.1|6258227_6258704_+|hypothetical-protein
MSEATERPAPDADAWADACAEDLAAEQERRRAQYGPEPGSAAEELRKLLGAVTDKFAGLFDGPSGLSGMAAQGAVQQLISQAKAAVEPVIERNPEVFDHLAAAGGELLAAYRSAVEGHEKRWTSDAGRTGPGGKGTGPDGTGRDGDQGPGPTEHIDLD
>CP032698.1|AYG83405.1|6258833_6259787_+|Glucokinase
MGLTIGVDIGGTKIAAGVVDEEGNILSTHKVPTPGTPDAIVDAIASAVDGARVGHEIVGVGIGAAGYVNRQRSTVYFAPNIDWRQEPLKEKVELRVGLPVVVENDANAAAWGEYRFGAGKGHRNVICITLGTGLGGGIIIGNKLRRGHFGVAAEFGHIRMVPDGLLCGCGSQGCWEQYASGRALVRYAKQRANATPERAEFLLGLGDGTPEGIEGKHISMAARQGDPVAVDSYRELARWAGAGLADLASLFDPSAFIVGGGLSDEGELVLDPIRKSYKRWLVGGNWRPVADVIAAQLGNKAGLVGAADLARQPDPIM
>CP032698.1|AYG83406.1|6259871_6260621_+|hypothetical-protein
MTTPDGGLPASATESGSAVIRVLSYNIRSMRDDNAALARVIRACAPDLVLIQEAPRFFRWRKAAARLAAATDLVILGGGATAAGPMLLCSLRATVEQTEDVLLPLTPGLHRRGFATAVVRIGGARIGVLSAHLSLQEAERYEQTGALLDRLAGMGVDHAIAGGDLNERPDGRGFRRLAGALQDCWEVAPWGGEFTSTPADPHQRIDAIFATAGVEVLGCGVPLGLAAPADLRTATDHLPVLAALRVPGA
>CP032698.1|AYG83407.1|6260914_6261274_+|hypothetical-protein
MVGIVERLVPDELWELFQRVVPEAPSRPQGGGRRRHGDREVLAAIVFVATSGCTWQQLPSASFGPSGATAHRRFSEWSKARVWAKLHRLVLDELGARGELDWSRCAIDSVNMRALKRGT
>CP032698.1|AYG83408.1|6261225_6261723_+|hypothetical-protein
MRDRLGEHAGPEKGDLTGPNPVDRGKYGSKIHLITERSGLPISVGISGANLHDSQALIPLVKGIPPIRSRRGPRRRKPSKLHADKGYDYAHLRQWLRERGITHRIARKGVESSQRLGRHRWTVERTMAWLAGCRRLHRRYERKADHFLAFTSIACTLICYRRLAK
>CP032698.1|AYG83409.1|6262049_6262652_-|hypothetical-protein
MAEHDADREPQPIDEEAAWAAIVAGYGEEPADPPGTRPFRSVEDLALIEDETAEEGEGPDPAVKTKGPGKGLDKPALGSSVVFAPGVGGPRDFTPADPAGDGAGAPDPSDPSDPSDPSDEGHFVPPEPPPLPEADAAAKFAWLGVIGGPLLLILAAIFGWDMTWWLTTLGVGGFLGGIATLFARMQPDEDDDDPGRGAVV

Crispr_ID: CP032698_87

• CRISPR_ID: CP032698_87
• CRISPR_location: 6294692-6294792
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_87

Consensus_repeat	Method
CCCTGGGGCTCCGCCCCAGACCCCG	CRISPRCasFinder

spacers of CP032698_87

>87.1|6294717|51|CP032698|CRISPRCasFinder
AGCCCTTTTGCCCACCCACCCGCCCGTGCAGCGGGTTGGTTGGTTCCGGCC

CRISPR arrays and Neighbor proteins around CP032698_87

CRISPR arrays

The CRISPR arrays of CP032698_87

>merge|CP032698|87|6294692-6294792|CRISPRCasFinder
CCCTGGGGCTCCGCCCCAGACCCCGAGCCCTTTTGCCCACCCACCCGCCCGTGCAGCGGGTTGGTTGGTTCCGGCCCCCTGGGGCTCCGCCCCAGACCCCG

>CP032698|87|63|6294692-6294792|CRISPRCasFinder
CCCTGGGGCTCCGCCCCAGACCCCG	AGCCCTTTTGCCCACCCACCCGCCCGTGCAGCGGGTTGGTTGGTTCCGGCC
CCCTGGGGCTCCGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83442.1|6299028_6300039_-|hypothetical-protein	unknown	unknown	gnl|CDD|223786
CP032698.1|AYG83437.1|6292460_6293000_+|hypothetical-protein	unknown	unknown	gnl|CDD|376149
CP032698.1|AYG83445.1|6302184_6304620_+|Penicillin-binding-protein-PbpB	unknown	unknown	gnl|CDD|223839
CP032698.1|AYG83448.1|6307710_6308781_+|Phospho-N-acetylmuramoyl-pentapeptide--transferase	unknown	unknown	gnl|CDD|234638
CP032698.1|AYG83434.1|6288777_6289386_-|HTH-type-transcriptional-repressor-KstR2	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG83431.1|6285430_6286276_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83438.1|6293161_6293920_+|tRNA-5-carboxymethoxyuridine-methyltransferase	unknown	unknown	gnl|CDD|182918
CP032698.1|AYG83432.1|6286306_6287842_-|Dehydrosqualene-desaturase	unknown	unknown	gnl|CDD|224154
CP032698.1|AYG83443.1|6300256_6300748_-|Beta-carbonic-anhydrase-1	unknown	unknown	gnl|CDD|239474
CP032698.1|AYG83435.1|6289397_6291482_-|ESAT-6-secretion-accessory-factor-EsaA	unknown	unknown	gnl|CDD|274414
CP032698.1|AYG83447.1|6306307_6307714_+|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	unknown	unknown	gnl|CDD|223841
CP032698.1|AYG83449.1|6308762_6310202_+|UDP-N-acetylmuramoylalanine--D-glutamate-ligase	unknown	unknown	gnl|CDD|179297
CP032698.1|AYG83439.1|6294227_6294617_+|hypothetical-protein	unknown	unknown	gnl|CDD|378610
CP032698.1|AYG83440.1|6295256_6297665_-|Protein-glutamine-gamma-glutamyltransferase	unknown	unknown	gnl|CDD|376628
CP032698.1|AYG83430.1|6284504_6285368_+|5,10-methylenetetrahydrofolate-reductase	unknown	unknown	gnl|CDD|366988
CP032698.1|AYG83433.1|6287849_6288467_-|hypothetical-protein	unknown	unknown	gnl|CDD|379253
CP032698.1|AYG83446.1|6304635_6306303_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	unknown	unknown	gnl|CDD|234660
CP032698.1|AYG83444.1|6301201_6302188_+|Ribosomal-RNA-small-subunit-methyltransferase-H	unknown	unknown	gnl|CDD|234597
CP032698.1|AYG83436.1|6291453_6292233_-|SkfA-peptide-export-ATP-binding-protein-SkfE	unknown	unknown	gnl|CDD|213186
CP032698.1|AYG83441.1|6297661_6299029_-|hypothetical-protein	unknown	unknown	gnl|CDD|224635

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83442.1|6299028_6300039_-|hypothetical-protein	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	6.28334e-95
CP032698.1|AYG83441.1|6297661_6299029_-|hypothetical-protein	gnl|CDD|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	6.92093e-25
CP032698.1|AYG83445.1|6302184_6304620_+|Penicillin-binding-protein-PbpB	gnl|CDD|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	2.52164e-138
CP032698.1|AYG83448.1|6307710_6308781_+|Phospho-N-acetylmuramoyl-pentapeptide--transferase	gnl|CDD|234638	PRK00108, mraY, phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional.	1.79193e-161
CP032698.1|AYG83434.1|6288777_6289386_-|HTH-type-transcriptional-repressor-KstR2	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	5.34015e-16
CP032698.1|AYG83437.1|6292460_6293000_+|hypothetical-protein	gnl|CDD|376149	pfam18726, HEPN_SAV_6107, SAV_6107-like HEPN. SAV_6107-like HEPN.	9.38353e-31
CP032698.1|AYG83438.1|6293161_6293920_+|tRNA-5-carboxymethoxyuridine-methyltransferase	gnl|CDD|182918	PRK11036, PRK11036, tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM.	8.08764e-22
CP032698.1|AYG83443.1|6300256_6300748_-|Beta-carbonic-anhydrase-1	gnl|CDD|239474	cd03379, beta_CA_cladeD, Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. CAs are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionarily distinct families of CAs (the alpha-, beta-, and gamma-CAs) which show no significant sequence identity or structural similarity. Within the beta-CA family there are four evolutionarily distinct clades (A through D). The beta-CAs are multimeric enzymes (forming dimers,tetramers,hexamers and octamers) which are present in higher plants, algae, fungi, archaea and prokaryotes.	6.12964e-58
CP032698.1|AYG83435.1|6289397_6291482_-|ESAT-6-secretion-accessory-factor-EsaA	gnl|CDD|274414	TIGR03062, hypothetical_protein_lp_1332, YhgE/Pip C-terminal domain. This family contains the C-terminal domain of a family of multiple membrane-spanning proteins of Gram-positive bacteria. One member was shown to be a host protein essential for phage infection, so many members of this family are called "phage infection protein". A separate model, TIGR03061, represents the conserved N-terminal domain. The domains are separated by regions highly variable in both length and sequence, often containing extended heptad repeats as described in model TIGR03057.	3.69928e-90
CP032698.1|AYG83449.1|6308762_6310202_+|UDP-N-acetylmuramoylalanine--D-glutamate-ligase	gnl|CDD|179297	PRK01438, murD, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional.	0
CP032698.1|AYG83439.1|6294227_6294617_+|hypothetical-protein	gnl|CDD|378610	pfam11239, DUF3040, Protein of unknown function (DUF3040). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed.	1.20433e-29
CP032698.1|AYG83440.1|6295256_6297665_-|Protein-glutamine-gamma-glutamyltransferase	gnl|CDD|376628	pfam01841, Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around conserved cysteine, histidine, and aspartate residues that form the catalytic triad in the structurally characterized transglutaminase, the human blood clotting factor XIIIa'. On the basis of the experimentally demonstrated activity of the Methanobacterium phage pseudomurein endoisopeptidase, it is proposed that many, if not all, microbial homologs of the transglutaminases are proteases and that the eukaryotic transglutaminases have evolved from an ancestral protease.	5.41049e-25
CP032698.1|AYG83430.1|6284504_6285368_+|5,10-methylenetetrahydrofolate-reductase	gnl|CDD|366988	pfam02219, MTHFR, Methylenetetrahydrofolate reductase. This family includes the 5,10-methylenetetrahydrofolate reductase EC:1.7.99.5 from bacteria and methylenetetrahydrofolate reductase EC: 1.5.1.20 from eukaryotes. The structure for this domain is known to be a TIM barrel.	5.16179e-139
CP032698.1|AYG83433.1|6287849_6288467_-|hypothetical-protein	gnl|CDD|379253	pfam13548, DUF4126, Domain of unknown function (DUF4126).	1.76461e-44
CP032698.1|AYG83432.1|6286306_6287842_-|Dehydrosqualene-desaturase	gnl|CDD|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.33641e-64
CP032698.1|AYG83446.1|6304635_6306303_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase	gnl|CDD|234660	PRK00139, murE, UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase; Provisional.	0
CP032698.1|AYG83444.1|6301201_6302188_+|Ribosomal-RNA-small-subunit-methyltransferase-H	gnl|CDD|234597	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH.	6.02967e-150
CP032698.1|AYG83436.1|6291453_6292233_-|SkfA-peptide-export-ATP-binding-protein-SkfE	gnl|CDD|213186	cd03219, ABC_Mj1267_LivG_branched, ATP-binding cassette component of branched chain amino acids transport system. The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).	1.46892e-17
CP032698.1|AYG83447.1|6306307_6307714_+|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase	gnl|CDD|223841	COG0770, MurF, UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane].	2.48717e-149

Protein sequences

>CP032698.1|AYG83439.1|6294227_6294617_+|hypothetical-protein
MPLSEHEQRMLEQMERALYAEDPKFATALEGSGLRTYTRRRVYQAVAGFLVGIALLMAGMVAQQIWISVVGFLVMLGCAVLAVTGWRKAPRPGEQVRPGGAAGPRQVRQRRSVMDRIEQRWQRRRDEGR
>CP032698.1|AYG83438.1|6293161_6293920_+|tRNA-5-carboxymethoxyuridine-methyltransferase
MSDPMRPRASLRTAVVWEVLKEALDRRVQATGRAALDVLDTGGGSGNFAVPLAALGHRVTVVDPSPNALFALERRAAEAGVAERVQGVQGDVLGLFDVVERGGYDAVLCHGVLEYVEDPAEGVRNAVDALRPEGALSLLAAGLGGAVISRALAGHFTEAQHALSDPAGRWGAGDPVPHRFTAERLTELVAAAGASAGAVHGVRVFADLVPGVLVDTEPGALDALLKLEAAAAELPAFHAIATQLHVLGEKRG
>CP032698.1|AYG83437.1|6292460_6293000_+|hypothetical-protein
MASSHAAAVPRRRASSPAPSLNGAATDVHPVLRRAGAPPAALDLLAQARGGLDEAAVLDAPNERYATAHLAALRTAAAVLAARGRPETTPRRRRRIRSAWEVLPEIAPELAEWSALFASGADRRARAEAGIPGAATTRDADDLLRDAAMFLRLVERLLVLQPVLPQARPGEPEAERRKG
>CP032698.1|AYG83436.1|6291453_6292233_-|SkfA-peptide-export-ATP-binding-protein-SkfE
MESSHADVTGAAIHAEGFGLKGPRGWAFRGVGVDAEPGSLVAVTGPSGSGRTCLLLALTGRMKPAEGRARVADQPLPRKMAAVRRISALAHVPGVSELDPAFTVAEHLRERVMLKRRYGGSVRALLRSPATRRAESRALIDDALAAAGLDLASLPKRGATAVRDLERLEALRLTVALALIQEPRLLAVDDTDMKLSDEERAAAWALLRSVADSGITVLAVCSESPAEADTTVRTTGSGAGDGATDEEGAADAFATTGSA
>CP032698.1|AYG83435.1|6289397_6291482_-|ESAT-6-secretion-accessory-factor-EsaA
MRSPRLAALELKRFGRGKLPRAALVALLLLPLLYGALYLCSFWDPYSRLDRIPVALVNDDKGAEAAGQKLQVGDELSKKLRDSKTFEWHEVSDAAAREGLEKGTYFLSLTVPSDFSQRIASSSGESPETGALQVHTNDANNYIVGSISRTVFAEVRAAASTKASRSFLDKIFISFGDLHDQTEKAAKGAGDLKDGLGKAKDGSKQLADGLKDAKDGSGKLAGGITLLDTGAGTLAGGAQQVADGTQRLADQANAAAGQARPYLKDNGKTVGDAAKLLADSIQPVRDNLKRIIELAPEAAAGTRKASQDVNALHQQLCVDQPADGKVCPVLSKAKKAMATGATLTADVNNLVKDQGGDFKKLDKSLEDLQTQARALAAKAPHLAGDLDQKIADVNKLNKGAHDVAKGARDIHTGLGKAKTGATDLDTGVGKLKKGAGALDGGIVKLSDGSVQLSNGLHDGVGKIPDYDKQQRDQRTEVMADPVKLASQAMHKAPNYGTGFAPYFIPLSLWVGAMVAYMLIAPLNRRALAAGASAWRIALAGWLPVAAIGLLQIAALMSVLHFGLGLEMERTAGTLGYLALASCCFTAIVQWLNAKFGAAGRILVLALLMLQLTSAGGTYPVQTSPAFFNAIHPYLPMSYVVDGLRRLITGGDLGVVWQGCAVLAAFTAGALALTALSARHKQVWSLDRLHPELSL
>CP032698.1|AYG83434.1|6288777_6289386_-|HTH-type-transcriptional-repressor-KstR2
MDSSSTRRQATRQKLYEAAVTLIAEQGFSATTVDEIAERAGVAKGTVYYNFKSKTELFEELLRHGVGLLTASLQAAADETDERGGTKVEALDAMIRAGLGFIHRYPAFTQLYVAELWRTNRAWQSTLLVVRREAVAVVETVLRDAVAEGELSEEIDIPLTAAALVGMVLVAALDWQAFQSERSLDDVHAALSRLLHGRVGGR
>CP032698.1|AYG83433.1|6287849_6288467_-|hypothetical-protein
MSVLPLVFTSGWASGINAYAVVLLLGIFGATGLTDEVPEALQRPDVLIVAGVLFLCEAVADKIPYVDSVWDSVHTVIRPIAGAVVGALLAGQNGSLPDLAAGAVGGSTALLSHLVKAGTRMAVNTSPEPFSNIALSTAEDLGVAGIISFAIFHPLAAAVIAGVLLLLGVVILVVLWRKIRRFRRRRAQRREEKRLAAAGVVRPPE
>CP032698.1|AYG83432.1|6286306_6287842_-|Dehydrosqualene-desaturase
MAADKVAGMARIVVIGAGMGAMAAAARLAVAGHRVTVYERSATYGGALGRFERDGFVFDTGPGLLRLPAVYRDLFVKTGKEPLESVVEPAPVDPAVRHVFADGTEVALPNASRAGVMSALDDALGAGAGERWGAFLVRAREAWDRTRRPLLEEPLWPNWEVLAREPYPALKQRRLLRAPRQAATLGEVAAWELGGGRLGALLESYALEYGLDPSTAPASAAVLPYMEQTFGSWYVRGGMRELARAVYERCLARKVEFVFGADVRLVREKDGRAAGVELADGAVIEADHVVCGADPRGLQRMLVERELWGADRVRPAAALGPSRFTVLLALRGGRPSTAAHRTVVHSPDAAAEARTAFAGPGTERPTVTVLRPDDPAVRPDEDHEAVTLTATVAPHGPVDWTDERLVLRYTEELIAAAEPAVPDLRERLLWHETRTPVDLARATGAEGGSVPAPSLAGAGAAFLHPANTTALPGLYTAGGWAHPGGGLAHAGMSGALVAGLIVEGDDFRGSQ
>CP032698.1|AYG83431.1|6285430_6286276_+|hypothetical-protein
MGWTVLYIAFGVVALWLLGEVLLQYKARLRWRLLAFTGFLGVVLGVLIPSVLVIIVGAIAFAVGQVYVTLSFRRGFSTGWALGGRPGASRRRKAGRRGAAAPEPVLEVSDLQYGEPAEADPFDPNGSAAPADSVYEPLPMPDETGQYGIYRPAQQSEGEGPAQYGAYDPHQPYADPYAPPYDETGTGQQQYAAYSDPYIGNGGQAYGTYSAYDSFGGQHSYPDPLAAQYGTDTPPGGVWVPQQRDGEYAPYEQQQAQPPYDPNHPNHTDLPHHPEQQPYRY
>CP032698.1|AYG83430.1|6284504_6285368_+|5,10-methylenetetrahydrofolate-reductase
MLATGETTYSFEFYAPKTEKGERNLWNALRRVEAVAPDFVSVTYGAGGTTRTGTVEATQQITEDTTLTPVAHLTAVGHSVAELRHTVGQYADAGIRNILAVRGDPKGDPMGEWVKHPQGVTYAAELVSLIRESGDFCVGVAAFPEMHPRSTDWDSDIRNFVDKCRAGADYAITQMFFEPENYLRLRDRVAAAGCETPIIPEVMPVTSVKQLERLPQLSTAVFPEELRARMLAVKDDPAAVRSIGIEFATEFCSRLLADGVPGLHFITLNNSTATLEIYENLGLHQQA
>CP032698.1|AYG83440.1|6295256_6297665_-|Protein-glutamine-gamma-glutamyltransferase
MSGRGRLALCAYLATVLAACSMLPLVDPASWILQAAFLLALVAGVGALARRVPLARPLTVLAQLVVALLLLTLVFARHQALGGVLPGPDAVERLNSLLQQGTSDVGQYAIPAPATPGIRLMMVGGVLIIGLAVDALAVTFRSAAPAGLPLLALYSVAAGLSSGGASWLWFVLAAAGYLLLLLAEGRDRLSQWGRVFGGAARAPGRAQQGVFDNAAPLAPVRTGRRIGVLALGIALVIPALLPALDGGLLGAAGGGGGGDGSGGTISAVNPLVSLQNSLNQPEDREVLRYNTNAEDTKELYLRIVALDEFDGASWKSSERHIKDVPDPLPRPDGLSPVVATTEVQTSVSAAGWYAQSWLPMPFPATQVKIKGDWRFEPVGRTLVGDRKQTTRGAQYTVGSLLIRPTAAQLANAAAPPAELLKEYTRVPDSLPSVVSATARQVTGGASNNYEKAVKLQDWFSTNGGFTYNTRVQSGSGTEAIANFLQEKEGFCVHFSFSMAAMARTLGIPARVAVGFTPGTPRADGTMSVGLRDAHAWPELYFQGVGWTRFEPTPTRGTAPDYTRQQAPAGSPSSPAEPSKRASAEPSAAPSVADSCPPAARRLGDCGPSAAAGVAAPTDGGPSASALLGVALGAVVLLALPLLPLLWRTRIRARRLGSGGRTPADAVARTLAAWQEITDTAWDHGILPDESQTPRKAAARVVRLGGLDGAAAESAHRAASAVEQVLYAPVPQPTPGLVDDVARVTSGLRARATRRQTLRAILAPRSAVRVIWAGALRWGRVRGALSGFARTTGTRLRPGSPRG
>CP032698.1|AYG83441.1|6297661_6299029_-|hypothetical-protein
MEAGGLPAESADEQARGGLWAALAGLTTRGRSFLAAGVAAAICAFVLGQEDLLRVGLLLAVLPLVCTVVLYRTRYRVAGSRRLAPGRVPAGSEARVHLRLDNVSRLPTGLLMLQDRVPYVLGPRPRFVLDRVEAGGKREVSYRVRSDLRGRYPLGPLQLRLTDPFGMCELTRAFSAYDTLTVIPRTEPLPPVRLSGEAAGYGDGRHRSLALAGEDDVIPRGYRHGDDLRRVHWRSTARYGELMVRREEQPQRARCTVLLDTRDIAYAGAGPDSAFEWAVSGAASALTHMLERGFSVRLLTDTGSSVPGDGAGGFAGSTQDSSDSAGLMMDTLAVVDHSDGGGLSRAYDVLRGGNEGLLIGFFGDLDEEQAAVAAKMRRRSGAAVAFVLDSGLWTHGSPERGPVEERLRLLREAGWTALQVSPGASLPELWRQAGRERGVTGAASGGAVGTAGGWS
>CP032698.1|AYG83442.1|6299028_6300039_-|hypothetical-protein
MTTYDDRASLSDLTATAERVRGSVERVIEGKPEVVRLSLTVLLAEGHLLIEDVPGVGKTMLAKTLARSIDCSVRRIQFTPDLLPSDITGVSIYDQQRRDFEFKPGAIFAQIVIGDEINRASPKTQSALLESMEERQVTIDGQTYELPSPFMVVATQNPVEMEGTYPLPEAQRDRFMARVSMGYPTPEAELQMLDVHGAVSPLDDLQPVAHAHEIVKLIDAVRGVHVADAVRRYAVQLVGATRNHPDLRLGASPRATLHLLRAAKASAALSGREYALPDDVQALAVAVLAHRLLPTAQAQLNRRTAEQVVLEILQHTPVPQAGNPLYGQQPPGARRL
>CP032698.1|AYG83443.1|6300256_6300748_-|Beta-carbonic-anhydrase-1
MTDRLVEANRQYAAAFTDPGMDARPVLHVAVVACMDARLDLHAALGLELGDCHTIRNAGGVVTDDVIRSLTISQRALGTTSVMLVHHTGCGMETLTEDFRHALEQEVGQRPAWAVESFRDADQDVRQSMQRVRTSPFLPHVDDVRGFVFDVTTGLLREIDPVA
>CP032698.1|AYG83444.1|6301201_6302188_+|Ribosomal-RNA-small-subunit-methyltransferase-H
MRGGAPDLERAALSQRHVPVMLQRCLDMLAPALTEPGAVVVDCTLGLGGHSEALLTRFPEARLIALDRDKEALRLSAERLAPFGERATLVHAVYDELPDVLERLGTPRVQGVLFDLGVSSMQLDEADRGFAYAQDAPLDMRMDQSTGMSAAEVLNTYPPGELVRILRAYGEEKQAKRIVSAIVREREKEPFSNSARLVELIRDALPQAAKRTGGNPSKRTFQALRIEVNGELASVERAIPAAVDAIALGGRVAVLSYQSLEDRIVKQVFAAGAANTAPPGLPVVPERYQPRLKLLTRGAELPTEEEVAENRRAAPARLRGVQRIREDV
>CP032698.1|AYG83445.1|6302184_6304620_+|Penicillin-binding-protein-PbpB
MSKPAMQLRGTAARLGRLMPSQGANSAARTPFVLLVVALLGGGLITLLVLNSALNEGSFKLSEYRRQTTELTDEQQALQRDVDDLSAPDALSRRAGDLGMVPGGNPVFLGPDGTVKGVPGTAGDPSPAEAAEPAPLPGAPSQAPAPRPKQRHTPAPSPAGRRRPPRPPAGDAVSPKEPPRRRVPPPARSRPPARRPPAAKKLKLGSHRPRLRLVSLGLTLVMLAFVVRLLQVQAVDASAYAAKADKNRYASYALPAERGRITDRAGIALATSVDAYDITADPTLFTPESAKIPDAAEQAAALLAPLIGKGQAELAKKLKTPRTRYVVLARRQTPQVWNQIKDLKKVLGEKAAADRAKGGPGANVLAGVLNESSTKRVYPNGDLAAGILGYVNAEGKGGGGLESSLNKELAGTDGKISYAQSGGRRVPTAGTRETPAVPGSDVELTIDRDIQWMAQKAIADQVAESRADRGYVIVQRSDTGEVLAMANAPGFDPNNIAQANAAAMGNAALQDAFEPGSTAKVMSMAAVLEEGVATPDTHVVVPNRLQRGDRLFKDDVDHATWNLTLNGVLAKSSNIGTILAVEQLGKTDAQADGVLYSYLRKFGIGSPSGLGFPGETPGILAPANKWSTSQQYTVRFGQGLSLNAMQAASVYSTIANGGVRIEPTLVRGTKGPDGRFTPAPPPRQTRVVSEKTAKTLAQMLESVVGDAEGTGTKAAIPGYRVAGKTGTANRVDPKTGTYKGYTASFAGFAPADNPKITVYCAIQNPTRGSYFGGQICGPIYKQVMEFALKTLQIPPSGAQPPNLPVTFGGND
>CP032698.1|AYG83446.1|6304635_6306303_+|UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,-6-diaminopimelate-ligase
MTTITRGPGNQDGTQDAVPPSFGDPTGAPGTLTAVPHADQYRTAQQDAPAKQPGAPRPEQARPTPLGELAERLGTNSPGSGEVTGITHDSRAVRPGDLYAALPGANTHGADFAAQAASLGAVAVLTDPAGRERAAATGLPVLVAGDPRGRMGELAAEIYGHPGRDLLQLGITGTSGKTTTAYLVEGGLRGAGHATGLIGTVEMRIGDERIKSERTTPEATDLQALFAVMRERGVDSVAMEVSSHALVLGRVDGCVFDVAVFNNLSPEHMEFHSDMEDYFQAKAQLFTPRRAKRGVVNFDDEYGRRLVKEAGIEITTFSAEGHPDADWRAEDVQVRQDSSTFTVVTPQGERISATAPLPGPFNVANTLAAVVTLAVAGLDPQTAADGVAAVPGVPGRLERVDAGQPYLAVVDYAHKTDAVESVLRSLRKVTEGKLHIVLGCGGDRDKTKRAPMGAAAARLADTAVLTSDNPRSEDPLAILAAMLAGAAEVPAHERGEVQVFEDRAAAIASAVARAEPGDTVLVAGKGHEQGQDIHGVVRPFDDRLVLRAAIQKSQG
>CP032698.1|AYG83447.1|6306307_6307714_+|UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D--alanine-ligase
MIALSLAEIAAIVGGQPHDIPDPSVTVTGPVVIDSRQVAAGSLFVAFAGEHVDGHDYAQRAFEAGAVAVLAARPVGVPAIVVDDVQGALGALARDVVRRLGTDVVALTGSSGKTSTKDLIAQVLQRHAPTVFTPGSLNNEIGLPLTALTAGPETRHLVLEMGARGVGHIRYLTGLTPPTIGLVLNVGSAHIGEFGGREQIALAKGELVESLPEGGCAVLNADDPLVRAMASRTKARVLLFGEAEDADVRAENVRLTAAGQPSFSLHTPSGCGDVTLRLYGEHHVSNALAAAAVAHELGMSADEIARALSEAGTLSRWRMEVTERPDGVTVVNDAYNANPESMRAALRALVAMGKGRRTWAVLGPMAELGDESLTEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSIGLERVAFALLDGAAEGEVAAR
>CP032698.1|AYG83448.1|6307710_6308781_+|Phospho-N-acetylmuramoyl-pentapeptide--transferase
MRQILFAGAIGLFLTLVGTPLLIKLLARKGYGQFIRDDGPRGHAGKKGTPTMGGIAFILATLIAYALTKVITSEDPTFSGLLVLFLTAGMGLVGFLDDYIKIVKQRSLGLRAKAKMAGQLIVGIAFAVLALQFADARGNTPASTKLSFINDFGWSVGPVIFVVWALFMILAMSNGVNLTDGLDGLATGASVMVFGAYTFIGLWQFQESCANAQTLTNPNACFEVRDPLDLAVVASALMGSCFGFLWWNTSPAKIFMGDTGSLALGGALAGLAICSRTEFLIALLGGLFVLITMSVVIQVGSFKMTGKRVFRMAPLQHHFELKGWSEVLVVVRFWIIQGMCVIVGLGLFYAGWAADK
>CP032698.1|AYG83449.1|6308762_6310202_+|UDP-N-acetylmuramoylalanine--D-glutamate-ligase
MGSRQVSTTWQGKRVTVAGLGVSGMPVAKVLAGLGAVVTAVNEGADERSRAQAAELEAQGVTVRLGDGATLPESTELIVTTPGWRPDKPLFAAAAKAGVPVWGDVELAWRLRDLDGRTPAPWLAVTGTNGKTTTTRMLASILEAAGLRTAAVGNIGVSLLDVVLGETQYDVLAVELSSYQLHWAPSLRAHSAAVLNLAPDHLDWHGSMEAYAADKGRIYEGNTVACVYNAEDKATEHLVREADVEEGCRAIGFTLATPGPSQLGVVDGILVDRAFVQNRQKNAQELAEVADVNPPAPHNIANALAAAALARAFGVEPKAVRDGLRAFRPDAHRIEHVADVAEVAYVDDSKATNTHAAEASLAAYDPIVWIAGGLAKGASFDELVQRSAKRLRGVVLIGAERHLIAEALARHAPEVPVVDLDRTDTGAMSAAVREAAGLARPGDTVLLAPACASMDMYANYNKRGEAFAEAVRGLTAGRA

Crispr_ID: CP032698_88

• CRISPR_ID: CP032698_88
• CRISPR_location: 6739078-6739176
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_88

Consensus_repeat	Method
CCCCTGGGGCTCCGCCCCAGACCCCG	CRISPRCasFinder

spacers of CP032698_88

>88.1|6739104|47|CP032698|CRISPRCasFinder
CGGGTTCGCCCACCCACCCGCCCGTGACGGGGGTTGGACAGCCCGGG

CRISPR arrays and Neighbor proteins around CP032698_88

CRISPR arrays

The CRISPR arrays of CP032698_88

>merge|CP032698|88|6739078-6739176|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCGCGGGTTCGCCCACCCACCCGCCCGTGACGGGGGTTGGACAGCCCGGGCCCCTGGGGCTCCGCCCCAGACCCCG

>CP032698|88|64|6739078-6739176|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCG	CGGGTTCGCCCACCCACCCGCCCGTGACGGGGGTTGGACAGCCCGGG
CCCCTGGGGCTCCGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83827.1|6730883_6731495_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83823.1|6728066_6728702_+|Fatty-acid-metabolism-regulator-protein	unknown	unknown	gnl|CDD|380061
CP032698.1|AYG83825.1|6729466_6729928_+|Redox-sensitive-transcriptional-activator-SoxR	unknown	unknown	gnl|CDD|133385
CP032698.1|AYG83830.1|6736282_6737650_-|hypothetical-protein	unknown	unknown	gnl|CDD|350610
CP032698.1|AYG83829.1|6734886_6736197_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83838.1|6745757_6746150_-|Inner-membrane-protein-YidH	unknown	unknown	gnl|CDD|225060
CP032698.1|AYG83837.1|6745437_6745758_-|hypothetical-protein	unknown	unknown	gnl|CDD|376882
CP032698.1|AYG83824.1|6728835_6729336_-|putative-enoyl-CoA-hydratase-1	unknown	unknown	gnl|CDD|239534
CP032698.1|AYG83840.1|6746785_6747682_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83839.1|6746175_6746691_-|putative-Nudix-hydrolase-YfcD	unknown	unknown	gnl|CDD|185291
CP032698.1|AYG83841.1|6747848_6749504_+|KsdD-like-steroid-dehydrogenase	unknown	unknown	gnl|CDD|183782
CP032698.1|AYG83828.1|6732035_6734870_+|Penicillin-G-acylase	unknown	unknown	gnl|CDD|376618
CP032698.1|AYG83832.1|6739841_6740615_+|1-deoxy-11-beta-hydroxypentalenate-dehydrogenase	unknown	unknown	gnl|CDD|212491
CP032698.1|AYG83833.1|6740611_6742264_+|Long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|341259
CP032698.1|AYG83834.1|6742403_6743000_+|HTH-type-transcriptional-repressor-KstR2	unknown	unknown	gnl|CDD|380061
CP032698.1|AYG83835.1|6743012_6744227_-|(R)-benzylsuccinyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173844
CP032698.1|AYG83836.1|6744236_6745259_-|Putative-aminoglycoside-phosphotransferase	unknown	unknown	gnl|CDD|270703
CP032698.1|AYG83822.1|6727695_6727995_+|hypothetical-protein	unknown	unknown	gnl|CDD|226748
CP032698.1|AYG83831.1|6737766_6739014_-|hypothetical-protein	unknown	unknown	gnl|CDD|377768
CP032698.1|AYG83826.1|6729998_6730736_-|hypothetical-protein	unknown	unknown	gnl|CDD|225785

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83823.1|6728066_6728702_+|Fatty-acid-metabolism-regulator-protein	gnl|CDD|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	1.46131e-35
CP032698.1|AYG83825.1|6729466_6729928_+|Redox-sensitive-transcriptional-activator-SoxR	gnl|CDD|133385	cd01110, HTH_SoxR, Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator. Helix-turn-helix (HTH) transcriptional regulator SoxR. The global regulator, SoxR, up-regulates gene expression of another transcription activator, SoxS, which directly stimulates the oxidative stress regulon genes in E. coli. The soxRS response renders the bacterial cell resistant to superoxide-generating agents, macrophage-generated nitric oxide, organic solvents, and antibiotics. The SoxR proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the unusually long spacer between the -35 and -10 promoter elements. They also harbor a regulatory C-terminal domain containing an iron-sulfur center.	1.32581e-76
CP032698.1|AYG83826.1|6729998_6730736_-|hypothetical-protein	gnl|CDD|225785	COG3246, COG3246, Uncharacterized conserved protein [Function unknown].	1.81691e-29
CP032698.1|AYG83830.1|6736282_6737650_-|hypothetical-protein	gnl|CDD|350610	cd14728, Ere-like, Erythromycin esterase and succinoglycan biosynthesis related proteins. This group contains erythromycin esterase, which shares conserved active site residues of the Tiki/TraB family. Erythromycin esterases (EreA and EreB) disrupt erythromycin via the hydrolysis of the macrolactone ring. A critical catalytic histidine acts as a general base in the activation of a water molecule. Macrolides act by inhibiting bacterial protein synthesis by binding at the exit tunnel of ribosomal subunit 50s, blocking the translation of the polypeptide. Erythromycin esterase, typically found in integrons and transposons, confers antibiotic resistance through the disruption of the drug ring structure. EreB substrate profile is substantially broader than that for EreA, being able to also metabolize semisynthetic derivatives such as azalide azithromycin.	1.42721e-104
CP032698.1|AYG83838.1|6745757_6746150_-|Inner-membrane-protein-YidH	gnl|CDD|225060	COG2149, COG2149, Predicted membrane protein [Function unknown].	3.13928e-27
CP032698.1|AYG83837.1|6745437_6745758_-|hypothetical-protein	gnl|CDD|376882	pfam02656, DUF202, Domain of unknown function (DUF202). This family consists of hypothetical proteins some of which are putative membrane proteins. No functional information or experimental verification of function is known. This domain is around 100 amino acids long.	2.39247e-08
CP032698.1|AYG83824.1|6728835_6729336_-|putative-enoyl-CoA-hydratase-1	gnl|CDD|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	2.35956e-92
CP032698.1|AYG83841.1|6747848_6749504_+|KsdD-like-steroid-dehydrogenase	gnl|CDD|183782	PRK12834, PRK12834, putative FAD-binding dehydrogenase; Reviewed.	0
CP032698.1|AYG83839.1|6746175_6746691_-|putative-Nudix-hydrolase-YfcD	gnl|CDD|185291	PRK15393, PRK15393, NUDIX hydrolase YfcD; Provisional.	5.00668e-33
CP032698.1|AYG83828.1|6732035_6734870_+|Penicillin-G-acylase	gnl|CDD|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	2.47059e-76
CP032698.1|AYG83832.1|6739841_6740615_+|1-deoxy-11-beta-hydroxypentalenate-dehydrogenase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.31539e-40
CP032698.1|AYG83833.1|6740611_6742264_+|Long-chain-fatty-acid--CoA-ligase	gnl|CDD|341259	cd05936, FC-FACS_FadD_like, Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD. This subfamily of the AMP-forming adenylation family contains Escherichia coli FadD and similar prokaryotic fatty acid CoA synthetases. FadD was characterized as a long-chain fatty acid CoA synthetase. The gene fadD is regulated by the fatty acid regulatory protein FadR. Fatty acid CoA synthetase catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, followed by the formation of a fatty acyl-CoA. This is a required step before free fatty acids can participate in most catabolic and anabolic reactions.	2.56813e-179
CP032698.1|AYG83835.1|6743012_6744227_-|(R)-benzylsuccinyl-CoA-dehydrogenase	gnl|CDD|173844	cd01155, ACAD_FadE2, Acyl-CoA dehydrogenases similar to fadE2. FadE2-like Acyl-CoA dehydrogenase (ACAD). Acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACAD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. ACAD's are generally homotetramers and have an active site glutamate at a conserved position.	0
CP032698.1|AYG83836.1|6744236_6745259_-|Putative-aminoglycoside-phosphotransferase	gnl|CDD|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	1.39407e-98
CP032698.1|AYG83822.1|6727695_6727995_+|hypothetical-protein	gnl|CDD|226748	COG4298, COG4298, Uncharacterized protein conserved in bacteria [Function unknown].	3.58423e-21
CP032698.1|AYG83831.1|6737766_6739014_-|hypothetical-protein	gnl|CDD|377768	pfam07075, DUF1343, Protein of unknown function (DUF1343). This family consists of several hypothetical bacterial proteins of around 400 residues in length. The function of this family is unknown.	0
CP032698.1|AYG83834.1|6742403_6743000_+|HTH-type-transcriptional-repressor-KstR2	gnl|CDD|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	8.00598e-30

Protein sequences

>CP032698.1|AYG83831.1|6737766_6739014_-|hypothetical-protein
MTLPRRTLLTGALTTGATTTALGTSAPARAAAPTQTRTGFDHLTTTAYTDLTNQKVGLVTNPTGVTRDVRHFVDVMHADPRVHLVAVFGPEHGFRGTAQAGGSQGRYDDPATGLPVYDTYTKSGRALADIFGASGVDTVVFDIQDVGARFYTYIWTLYDCMEAAALAGKRFVVLDRPNPVTGRAAYGPVLDPAFASFVGRVPISQAHGMTAAELARLFNAEFLGGKVRLTTVRMSGWRRSDFFDRTGLPWVPPSPNMPTPDSALVYSGTCLFEGTNLSEGRGTTRSFELLGAEGLDGRWAAALDALALPGVRFREAYFAPTFSKFAGKTVGGVQLHVHERRLFDPVRTGIAALVTAKRVWAGFAWRPDHWVDKLTGSALVRTMIDAGASTDDIVAAWQPGLRAFRALRAEHLLYD
>CP032698.1|AYG83830.1|6736282_6737650_-|hypothetical-protein
MNLFTETLHRSRRSPLSGRGAVLLLLTLCLGLLTTVPPARAAPLPAGPALPSDPVRELARGAVPLSDPRPLGRMTAGADIVGLGEATHNSHEFFATKQRVFQYLVEQRGFTTFALEVSWSSGLRVNDYVRYGKGDPERVVHEEFQGSYTVWDTQEYLDLIRWMRGYNQHHPANQVQFMGDDMGYAGPALFDRVTAYTARHYPKLLPEIDRLYRQSRPTAGVGDTMMSYLRRPMNERQRMAADTARAYALLSAQHPGADAEAFDWVVQDARTIAQTGQQFGYDFDDPEQLRASRGYRDRVMAENTLWWQRHTGHRMLLSAHNGHVGYEPTGDGEYPKMQGAFLREAIGSRYVSIGFTFGQGSFNAFDLTDPAEPIRTFSVPPLGAGSNEEVLERVSPRDFYLDLRAASRPARAWLAVTRPTRSIGNAWPAEVERTRLGASFDILIHLHRVRAADRL
>CP032698.1|AYG83829.1|6734886_6736197_-|hypothetical-protein
MADIGVEPYREITFDADGDADPAERTALTGVDATDLVLFAHGWNNTPDTARGLYRAFFAPFPALLSGTSGVRLGYGGVTWPSIRFTDETIPNFPHATQTDPAPGLDERTVAALKGFFPGQDADVDRIAALLAQRPDAQEAFEEFGLLSRRLVTTGAGRAGAMGDLAAENGQGVSAAILTDDTLTLCQRFTAALADTGMPVEAGPPGPSFSIGGSLKHLWDGAKEVLRQLTYYEMKHRAGTVGQLGLGPLIGQLSLSRPDLRIHLVGHSQGARLVAFALKGLPRGARNVKSVTLLEGAFSHYAFAERLPDGLPGAGALSDAQDRADGPVVSCYSRSDTALGVIYPLASALSGDYASELPGLDRRWWAIGHDGIQAVTPCTTLTLAEALRDGVPDSGCVSVDASSVVKAGGPPSGSHSDICHPELARLVLAAGRIVRI
>CP032698.1|AYG83828.1|6732035_6734870_+|Penicillin-G-acylase
MRRRTARLTTAATTNRLRRVKGIGRGRAAACAATVIALSAALLGPAIPAGAAEPADGDHCQGQCSDILPPGANGNATLVEILGNKLFGTHPAHSDDELGKYDALVAGQSSLTDDKLNAFFNDASFGVPSGQVQSTSSPRPDVTITRDKATGVPHIKGTTRYGTEYGAGYAAGQDRLWLMDLFRHIGRGELTSFAGGALANQGLEQEFWPQAPYTEADLQAQVDRIRTGNGARGEQAMADAQAYVDGINAYAKQSKDGRYFPGEYVLTGKIDSITNVGEIQPFKLTDLIALASVVGGLFGGGGGGEVQAALSLQAAQAKYGVAEGTKVWESFRERDDPEAVLTVHDGTSFPYAGKPANARGTALPDPGSVVPEQLVYDRTGSANTQAKADVKAPPKLAPLKGMYDNGVLPGIDLGKPRGMSNALVVSGSHTASGHPVAVFGPQTGYFAPQLLMLQEIQGPGISARGASFAGVGMYVQLGRGQDYAWSATSAGQDITDTYAVELCQDATHYLYRGTCTPMEKMEKANSWKPTVADTTAAGSYRMQVWRTNYGIVTARATVGGKPVAYTSLRSTYRHDADSIIGFQMMNDPTFVKDAQSFQEAARSVDYTFNWFYADSRTAAYYNSGLNPVRNPDVDPSLPVKAEQAYEWQGFDPTSNTAGYTPPAQHPQSIGQDYYVSWNNKQAKEYSTAGFGDGSVHRANLLDDRVKALVAQGGVTRSSLTRAMAQAAVTDLRGEDVLPELLKVLHSAPVTDPQLATAVQQLDAWKADGTQRRETSQGSHTYTHPDAVRLMDAWWPLLVEAEFRPGLGDPLYNALTTNLGIDEAPSAGHGPTGSHAGSAFQYGWWSYVDKDLRTVLGEPVQGPLGRAFCGDGKPAACRDSLLGTLKQAAAKTPAQVYPGDAGCSAGDQWCADSIVQRPLGGITQSVINWQNRPTYQQVVEFPSHR
>CP032698.1|AYG83827.1|6730883_6731495_-|hypothetical-protein
MAGFRSLARQVRDPRNDLALRRYSLRKCLERFAPYGHRATWDHLCRRHRIGPEDRAPDPARLVAALEELEAARAVWLAYEVEFAARRKREKHAGLRRPGSFDDWHRRTWGGFGVAWCDDPRTHPVEPLAVVLGRMIAALRAQPGTLCPVCRESRLVWSQDLSHEPWFGPVCSGCGILVPQPVLTPEALSRAKAARRGELASVA
>CP032698.1|AYG83826.1|6729998_6730736_-|hypothetical-protein
MSVGSGTLEDMIQVCLNGARGAADGAMVPLSPAALARSAADAVAAGAAEIHVHPKTPCGDDSLSPGVVGPALEAIRAVVSVPVGVTTGAWAEPDPARRVERVKSWTVLPDYASVNWHEEGAEAVAAALLDRGVGIEAGIWSGTDAARRFLASPLGPRVLRVLAEVTDPAQGAAEPTARALLAELGAAHGRPVLLHGEDDHAWPVLRLALALGLDTRVGLEDVLVLPDGQRAASNAQLVSAALGRA
>CP032698.1|AYG83825.1|6729466_6729928_+|Redox-sensitive-transcriptional-activator-SoxR
MPQIPEKIHELTVGQLSARSGAAVSALHFYETKGLIVSRRTSGNQRRYGRDTLRRVAFIRAAQRVGIPLATIRDALAALPEERTPTKEDWALLSENWRAELDRRISQLGRLRDHLSDCIGCGCLSLDTCVLSNPDDVFGTSRTGSRLLAERKA
>CP032698.1|AYG83824.1|6728835_6729336_-|putative-enoyl-CoA-hydratase-1
MTVRASREAGTKDMAEPRIFTSAEELKAGVGEQLGHSDWLEIDQKRIDLFADATGDHQWIHVDPARAATGPFGTTIAHGYLTLSLLPTLVPQVLRVEGMKMGINYGTNKVRFPSPVPVGSRLRATAELTEVVEAGGGVQVTAKVTVEREGGDKPVCVAESVSRYFF
>CP032698.1|AYG83823.1|6728066_6728702_+|Fatty-acid-metabolism-regulator-protein
MGTADVTEETAGGEEKPWGEVTPEAARRLLVAAVEAFAERGYHATTTRDIAGRAGMSPAALYIHYKTKEELLHRISRIGHDKALEILRSAAEGEGSAAERLSAAVRSFVRWHAGHHMTARVVQYELDALGAEHRGEIVELRRQSDAAVRRILGDGVAAGEFDVPDVPGTTLAVLSLCIDVARWFNTEGRRTPDEVGALYADLVLRMVGAQK
>CP032698.1|AYG83822.1|6727695_6727995_+|hypothetical-protein
MLSVMSETPVKQQNTAAYYGQAVAAFSIALVATAIGILRLQADAWVRAFLAMAVLYLVTSAFTLAKVIRDRQEAGQIVSRVDQARLEKLLAEHDPFQKL
>CP032698.1|AYG83832.1|6739841_6740615_+|1-deoxy-11-beta-hydroxypentalenate-dehydrogenase
MSTGQTAEGTTVVVTGAGGGIGAALARRFAAQGARVVVNDLDADKARRTAEEIGAIAVPGDASTVVGAARDALGGTIDVYCANAGLGSGGSESAPEDVWAAAWDVNVMAHVRAARELLPDWLERGRGRFVSTVSAAGLLTMIGAAPYSVTKHGALAFAEWLSLTYRHRGIQVHAICPQGVRTDMLADTGTAGDLVLKPTAIEPDEVADALFAAMAEDRFLVLPHPEVADYYTARAATPDRWLTSMNHLQQKWEASAG
>CP032698.1|AYG83833.1|6740611_6742264_+|Long-chain-fatty-acid--CoA-ligase
MSSIYATKPWLSQLSAAQRADIDPPETVLDSFRAAVARAPEHTALAYFDGRLSYREVDELSDSVAGHLAARGLVRGDRVALMLQNSPHFVIALLGAWKAGATVVPLNPMYKAGEVAHVLHDAEAAALICSDRAWEGYLRDTAADSPVRVALTACELDLQSRDDERVLGFERLPVAADADDLLAVARQGLAAPSGRELGGGDTALISYTSGTSGTPKGAMNTHRGITYQAERQRTGHPIPPGAGYFALAPLFHITGMVCELATCVANAGTLVLTYRFHPGVVLDAFVEHRPAYTVGPSTAFMALAATPGATPEHFASFKLISSGGAPLPPALVEKFREGFGPYIRNGYGLTECTAPCASVPPEKEAPVDPVSGTLSVGVPGPETVVRIVGPEGKEVPFGEQGEIVVRGPQVVPGYWRRPEATVEAFPDGELRTGDIGFMDRDGWLYVVDRMKDMINASGFKVWPREVEDVLYSHPAVREAAVVGIPDSYRGESVKAYVSLRPGAEAGPAELAAYCKERLAAYKYPREVEILAELPKTTSGKILRRELRTQA
>CP032698.1|AYG83834.1|6742403_6743000_+|HTH-type-transcriptional-repressor-KstR2
MAKATDTSGTTPVPQRLLAAATRLFAENGYDRTSVQEIVEAAGVTKGALYHYFGSKEDLLQEVYARVLRLQQERLDAFADADEPIERRLREAAADVVVTTIDNLDDAAIFFRSMHHLSPEKNKQVRAERRRYHERFRALVEEGQNAGVFSTATPADLVVDYHFGSVHHLSTWYRPDGPLTQQQVADHLADLLLRALRP
>CP032698.1|AYG83835.1|6743012_6744227_-|(R)-benzylsuccinyl-CoA-dehydrogenase
MDFAYDARTEELRATLLAFMDEYVHPAEVTAHEQRAQLASPWDTPQVVEDLKAEARRQGLWNLFLPDAEHGAGLTNLQYAPLAEITGRSPHLAPTALNCAAPDTGNMEALAQFGSDEQKKQWLQPLLAGEIRSAFAMTEPEVASSDATNIETRIERDGDDYVITGRKWYISGAMNPDCAIFIVMGKTDPGNADVRRQQSMVLVPRDTPGVEIRRAMQVYGYEDHSHGGHAEVVFHGARVPASNLIGEAGGGFAIAQARLGPGRIHHCMRLIGMAERAIELMCRRAVSRTAFGKPMAQQGVVQEWIADARVAVEQVRLLVLKTAWLMDTVGNRGAHTEIQAIKIATPRTVLDIIDKAIQLHGAGGVSQDFPLAELWASARTLRLADGPDEVHQRSLARRELKKYL
>CP032698.1|AYG83836.1|6744236_6745259_-|Putative-aminoglycoside-phosphotransferase
MSTVPPPGLDPETLRAHLDRVRPGLVSGPLTARLIEGGRSNLTYVVTDGTGQWVVRRPPLGHVLATAHDMRREHRVISALHPTAVPVPEPVLLCEDESVLGSPFYVMEYVTGTPYRTAEQLAPLGPERTRAAVLALVDTLVELHAVDPQAVGLGDFGRPEGFLDRQLRRWGKQLDASRNRDLAGIDELHAALGRALPTSPAPTVIHGDYRLDNVLIGDDERIKAVLDWEMSTLGDPLTDLGLLVMYSAKLELPHSPVSTTAGAAGHPSPAELIERYAARSGRDTSALSWYTAFAWFKLAVILEGIHYRYTLGQTVGAGFDRIGELVPVFIEHGLTTLQEG
>CP032698.1|AYG83837.1|6745437_6745758_-|hypothetical-protein
MPSAVSARDPGLQPERTRLAWRRTTLSCTVAAVLAAKQALRQGSSPLALVAVALSGLVWLGFLAVAHRRIQALSHGVRPRMLGVRSAAAAALCTVALACFALATLF
>CP032698.1|AYG83838.1|6745757_6746150_-|Inner-membrane-protein-YidH
MITIVQTLRLWFAPQRIGEEGETPDYRFSLANERTFLAWIRTSLALVGGGFAVDQFLPDLRWGVRVALALALLAAGVLCALRAVNHWVRCERAMRRGEDLPVSRFPTLLSLAVAVVAVVMVVVVVFGWAG
>CP032698.1|AYG83839.1|6746175_6746691_-|putative-Nudix-hydrolase-YfcD
MNPADEILDIVDENDTVIGQARRAEVYARGLRHRCVFILARDAAGRIFVHRRTPDKLVFPSLYDMFVGGVVGAGESYDDAALREAEEELGVQGLPRPAPLFTFLYENGEQSWWSSVYEVRCEVPVHPQVEEVAWHTFLPLAEVERRIDTWEWVPDGLAAWRRLRASGLGPS
>CP032698.1|AYG83840.1|6746785_6747682_-|hypothetical-protein
MSVLVLVLAVSAACCLGSGFVLQQNAAQHAPISDFLSPRLLLDLVRMPRWLAGIGLMVAGMVLSALALGSGEVSLVEPLVATNLFFAMWLSRLQTRQPLGRQGWAGLALLAGGVTAFIVAGQPHGGVAEAGALRHWLIVGLVVGIALLMAGLAKHDRLSVAAPVLLAVAAGLLYGLQDALTRISGQRLSGGGWSELLTSWQLYGVIALGVTGLVLVQSAFETAPLRMSLPALTAAQPLAGIACGVGFLGDRLRTDTGALAWEAAGLAAIVTGIVLLGLHPAMPSGTASPEESRDLQPH
>CP032698.1|AYG83841.1|6747848_6749504_+|KsdD-like-steroid-dehydrogenase
MAYDADVIVIGAGLAGLVATAELADAGRKVILLDQEPEQSLGGQAHWSFGGLFLVDSPEQRRMRIKDSRALALQDWYGTAGFDRDEDRWPRAWAEAYVDFASGEKRAWLHAQGVRFFPVVGWAERGGYDANGHGNSVPRFHITWGTGPGIVAPFERRVREAAARGLVRFGFRHRVTGLGRSAGVVDTVSGEILEPSGAERGTASTRTVTGSFELTAQAVIVTSGGIGGNHDLVRAQWPQRLGTPPEHLLSGVPAHVDGLMLGITEKAGAHHINRDRMWHYTEGIQNWNPIWARHGIRILPGPSSLWLDARGNRLPVPLFPGFDTLGTLDHIMKTGYGHTWFVLDQKIIGKEFALSGSEQNPDLTGKSVRGVIGRARADVPGPVRAFMDRGADFVVEKDLAALVRGMNALTEEPLLDEAALRREIVARDREIANPFTKDLQVTAIRGARNYLGDKLIRTAAPHRILDPKAGPLIAVKLHILTRKSLGGLETDLSSRVLTATGEPLPGVYAAGEAAGFGGGGVHGYRSLEGTFLGGCLFSGRAAGRAAAKAVS

Crispr_ID: CP032698_89

• CRISPR_ID: CP032698_89
• CRISPR_location: 6739253-6739675
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 7 spacers

Consensus repeat of CP032698_89

Consensus_repeat	Method
AGGGGCGCGGGGAACTGCGCGA	CRT
GGGGTTAGGGGCGCGGGGAACTGCGCGATCAGCCACGCACGGTGTG	PILER-CR

spacers of CP032698_89

>89.1|6739275|37|CP032698|CRT
CCAGCCCCCCACGACCCGCAGCCGAAAACGGGTTTTC
>89.2|6739334|35|CP032698|CRT
GAAGCGACCACGGCCCGCAGGCCGAGAGCGGGGTT
>89.3|6739391|37|CP032698|CRT
CCAGCCACGCACGGTGCGAGGACGAAAACGGGTTTTG
>89.4|6739450|35|CP032698|CRT
GAAGCGACCACGGCCCGCAGGCCGAGAGCGGGGTT
>89.5|6739507|35|CP032698|CRT
GACGCGGGCACGGTCCGCGGACGGCCGAGCACCTA
>89.6|6739564|34|CP032698|CRT
TCAGCCACGCACGGTGTGAGGGCGCAAGGGGGTT
>89.7|6739620|34|CP032698|CRT
TCAGCCACGCACGGTGTGAGGGCGCAAGGGGGTT
>89.8|6739528|35|CP032698|PILER-CR
GACGCGGGCACGGTCCGCGGACGGCCGAGCACCTA
>89.9|6739612|10|CP032698|PILER-CR
AGGGCGCAAG

CRISPR arrays and Neighbor proteins around CP032698_89

CRISPR arrays

The CRISPR arrays of CP032698_89

>merge|CP032698|89|6739253-6739675|CRT,PILER-CR
AGGGGCGCGGGGAACTGCGCGACCAGCCCCCCACGACCCGCAGCCGAAAACGGGTTTTCAGGGGCGCGAGGAACTGCGCGAGAAGCGACCACGGCCCGCAGGCCGAGAGCGGGGTTAGGGGCGCGGGGAACTGCGCGACCAGCCACGCACGGTGCGAGGACGAAAACGGGTTTTGAGGGGCGCGAGGAACTGTGCGAGAAGCGACCACGGCCCGCAGGCCGAGAGCGGGGTTAGGGGCGCGGGGAACTGCGCGGGACGCGGGCACGGTCCGCGGACGGCCGAGCACCTAAGGGGCGCGGGGAACTGCGCGATCAGCCACGCACGGTGTGAGGGCGCAAGGGGGTTAGGGGCGCGGGGAACTGCGCGATCAGCCACGCACGGTGTGAGGGCGCAAGGGGGTTGGGGGCGCGGGGAAGTGGTACG

>CP032698|89|11|6739253-6739675|CRT
AGGGGCGCGGGGAACTGCGCGA	CCAGCCCCCCACGACCCGCAGCCGAAAACGGGTTTTC
AGGGGCGCGAGGAACTGCGCGA	GAAGCGACCACGGCCCGCAGGCCGAGAGCGGGGTT
AGGGGCGCGGGGAACTGCGCGA	CCAGCCACGCACGGTGCGAGGACGAAAACGGGTTTTG
AGGGGCGCGAGGAACTGTGCGA	GAAGCGACCACGGCCCGCAGGCCGAGAGCGGGGTT
AGGGGCGCGGGGAACTGCGCGG	GACGCGGGCACGGTCCGCGGACGGCCGAGCACCTA
AGGGGCGCGGGGAACTGCGCGA	TCAGCCACGCACGGTGTGAGGGCGCAAGGGGGTT
AGGGGCGCGGGGAACTGCGCGA	TCAGCCACGCACGGTGTGAGGGCGCAAGGGGGTT
GGGGGCGCGGGGAAGTGGTACG

>CP032698|89|23|6739479-6739640|PILER-CR
GGGGTTAGGGGCGCGGGGAACTGCGCGGGACGCGGGCACGGTCCGCGGA	CGGCCGAGCACCTAAGGGGCGCGGGGAACTGCGCG
ATCAGCCACGCACGGTGTGAGGGCGCAAGGGGGTTAGGGGCGCGGGGAA	CTGCGCGATC
AGCCACGCACGGTGTGAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83827.1|6730883_6731495_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83823.1|6728066_6728702_+|Fatty-acid-metabolism-regulator-protein	unknown	unknown	gnl|CDD|380061
CP032698.1|AYG83825.1|6729466_6729928_+|Redox-sensitive-transcriptional-activator-SoxR	unknown	unknown	gnl|CDD|133385
CP032698.1|AYG83830.1|6736282_6737650_-|hypothetical-protein	unknown	unknown	gnl|CDD|350610
CP032698.1|AYG83829.1|6734886_6736197_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83838.1|6745757_6746150_-|Inner-membrane-protein-YidH	unknown	unknown	gnl|CDD|225060
CP032698.1|AYG83837.1|6745437_6745758_-|hypothetical-protein	unknown	unknown	gnl|CDD|376882
CP032698.1|AYG83824.1|6728835_6729336_-|putative-enoyl-CoA-hydratase-1	unknown	unknown	gnl|CDD|239534
CP032698.1|AYG83840.1|6746785_6747682_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83839.1|6746175_6746691_-|putative-Nudix-hydrolase-YfcD	unknown	unknown	gnl|CDD|185291
CP032698.1|AYG83841.1|6747848_6749504_+|KsdD-like-steroid-dehydrogenase	unknown	unknown	gnl|CDD|183782
CP032698.1|AYG83828.1|6732035_6734870_+|Penicillin-G-acylase	unknown	unknown	gnl|CDD|376618
CP032698.1|AYG83832.1|6739841_6740615_+|1-deoxy-11-beta-hydroxypentalenate-dehydrogenase	unknown	unknown	gnl|CDD|212491
CP032698.1|AYG83833.1|6740611_6742264_+|Long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl|CDD|341259
CP032698.1|AYG83834.1|6742403_6743000_+|HTH-type-transcriptional-repressor-KstR2	unknown	unknown	gnl|CDD|380061
CP032698.1|AYG83835.1|6743012_6744227_-|(R)-benzylsuccinyl-CoA-dehydrogenase	unknown	unknown	gnl|CDD|173844
CP032698.1|AYG83836.1|6744236_6745259_-|Putative-aminoglycoside-phosphotransferase	unknown	unknown	gnl|CDD|270703
CP032698.1|AYG83822.1|6727695_6727995_+|hypothetical-protein	unknown	unknown	gnl|CDD|226748
CP032698.1|AYG83831.1|6737766_6739014_-|hypothetical-protein	unknown	unknown	gnl|CDD|377768
CP032698.1|AYG83826.1|6729998_6730736_-|hypothetical-protein	unknown	unknown	gnl|CDD|225785

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83823.1|6728066_6728702_+|Fatty-acid-metabolism-regulator-protein	gnl|CDD|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	1.46131e-35
CP032698.1|AYG83825.1|6729466_6729928_+|Redox-sensitive-transcriptional-activator-SoxR	gnl|CDD|133385	cd01110, HTH_SoxR, Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator. Helix-turn-helix (HTH) transcriptional regulator SoxR. The global regulator, SoxR, up-regulates gene expression of another transcription activator, SoxS, which directly stimulates the oxidative stress regulon genes in E. coli. The soxRS response renders the bacterial cell resistant to superoxide-generating agents, macrophage-generated nitric oxide, organic solvents, and antibiotics. The SoxR proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the unusually long spacer between the -35 and -10 promoter elements. They also harbor a regulatory C-terminal domain containing an iron-sulfur center.	1.32581e-76
CP032698.1|AYG83826.1|6729998_6730736_-|hypothetical-protein	gnl|CDD|225785	COG3246, COG3246, Uncharacterized conserved protein [Function unknown].	1.81691e-29
CP032698.1|AYG83830.1|6736282_6737650_-|hypothetical-protein	gnl|CDD|350610	cd14728, Ere-like, Erythromycin esterase and succinoglycan biosynthesis related proteins. This group contains erythromycin esterase, which shares conserved active site residues of the Tiki/TraB family. Erythromycin esterases (EreA and EreB) disrupt erythromycin via the hydrolysis of the macrolactone ring. A critical catalytic histidine acts as a general base in the activation of a water molecule. Macrolides act by inhibiting bacterial protein synthesis by binding at the exit tunnel of ribosomal subunit 50s, blocking the translation of the polypeptide. Erythromycin esterase, typically found in integrons and transposons, confers antibiotic resistance through the disruption of the drug ring structure. EreB substrate profile is substantially broader than that for EreA, being able to also metabolize semisynthetic derivatives such as azalide azithromycin.	1.42721e-104
CP032698.1|AYG83838.1|6745757_6746150_-|Inner-membrane-protein-YidH	gnl|CDD|225060	COG2149, COG2149, Predicted membrane protein [Function unknown].	3.13928e-27
CP032698.1|AYG83837.1|6745437_6745758_-|hypothetical-protein	gnl|CDD|376882	pfam02656, DUF202, Domain of unknown function (DUF202). This family consists of hypothetical proteins some of which are putative membrane proteins. No functional information or experimental verification of function is known. This domain is around 100 amino acids long.	2.39247e-08
CP032698.1|AYG83824.1|6728835_6729336_-|putative-enoyl-CoA-hydratase-1	gnl|CDD|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	2.35956e-92
CP032698.1|AYG83841.1|6747848_6749504_+|KsdD-like-steroid-dehydrogenase	gnl|CDD|183782	PRK12834, PRK12834, putative FAD-binding dehydrogenase; Reviewed.	0
CP032698.1|AYG83839.1|6746175_6746691_-|putative-Nudix-hydrolase-YfcD	gnl|CDD|185291	PRK15393, PRK15393, NUDIX hydrolase YfcD; Provisional.	5.00668e-33
CP032698.1|AYG83828.1|6732035_6734870_+|Penicillin-G-acylase	gnl|CDD|376618	pfam01804, Penicil_amidase, Penicillin amidase. Penicillin amidase or penicillin acylase EC:3.5.1.11 catalyzes the hydrolysis of benzylpenicillin to phenylacetic acid and 6-aminopenicillanic acid (6-APA) a key intermediate in the the synthesis of penicillins. Also in the family is cephalosporin acylase and aculeacin A acylase which are involved in the synthesis of related peptide antibiotics.	2.47059e-76
CP032698.1|AYG83832.1|6739841_6740615_+|1-deoxy-11-beta-hydroxypentalenate-dehydrogenase	gnl|CDD|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	2.31539e-40
CP032698.1|AYG83833.1|6740611_6742264_+|Long-chain-fatty-acid--CoA-ligase	gnl|CDD|341259	cd05936, FC-FACS_FadD_like, Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD. This subfamily of the AMP-forming adenylation family contains Escherichia coli FadD and similar prokaryotic fatty acid CoA synthetases. FadD was characterized as a long-chain fatty acid CoA synthetase. The gene fadD is regulated by the fatty acid regulatory protein FadR. Fatty acid CoA synthetase catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, followed by the formation of a fatty acyl-CoA. This is a required step before free fatty acids can participate in most catabolic and anabolic reactions.	2.56813e-179
CP032698.1|AYG83835.1|6743012_6744227_-|(R)-benzylsuccinyl-CoA-dehydrogenase	gnl|CDD|173844	cd01155, ACAD_FadE2, Acyl-CoA dehydrogenases similar to fadE2. FadE2-like Acyl-CoA dehydrogenase (ACAD). Acyl-CoA dehydrogenases (ACAD) catalyze the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACAD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. ACAD's are generally homotetramers and have an active site glutamate at a conserved position.	0
CP032698.1|AYG83836.1|6744236_6745259_-|Putative-aminoglycoside-phosphotransferase	gnl|CDD|270703	cd05154, ACAD10_11_N-like, N-terminal domain of Acyl-CoA dehydrogenase (ACAD) 10 and 11, and similar proteins. This subfamily is composed of the N-terminal domains of vertebrate ACAD10 and ACAD11, and similar uncharacterized bacterial and eukaryotic proteins. ACADs are a family of flavoproteins that are involved in the beta-oxidation of fatty acyl-CoA derivatives. ACAD deficiency can cause metabolic disorders including muscle fatigue, hypoglycemia, and hepatic lipidosis. There are at least 11 distinct ACADs, some of which show distinct substrate specificities to either straight-chain or branched-chain fatty acids. ACAD10 is widely expressed in human tissues and highly expressed in liver, kidney, pancreas, and spleen. ACAD10 and ACAD11 are both significantly expressed in human brain tissues. They contain a long N-terminal domain with similarity to phosphotransferases with a Protein Kinase fold, which is absent in other ACADs. They may exhibit multiple functions in acyl-CoA oxidation pathways. ACAD11 utilizes substrates with carbon chain lengths of 20 to 26, with optimal activity towards C22CoA. ACAD10 may be associated with an increased risk in type II diabetes. The ACAD10/11-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	1.39407e-98
CP032698.1|AYG83822.1|6727695_6727995_+|hypothetical-protein	gnl|CDD|226748	COG4298, COG4298, Uncharacterized protein conserved in bacteria [Function unknown].	3.58423e-21
CP032698.1|AYG83831.1|6737766_6739014_-|hypothetical-protein	gnl|CDD|377768	pfam07075, DUF1343, Protein of unknown function (DUF1343). This family consists of several hypothetical bacterial proteins of around 400 residues in length. The function of this family is unknown.	0
CP032698.1|AYG83834.1|6742403_6743000_+|HTH-type-transcriptional-repressor-KstR2	gnl|CDD|380061	pfam17932, TetR_C_24, Tetracyclin repressor-like, C-terminal domain. TetR family regulators are involved in the transcriptional control of multidrug efflux pumps, pathways for the biosynthesis of antibiotics, response to osmotic stress and toxic chemicals, control of catabolic pathways, differentiation processes, and pathogenicity. The TetR proteins identified in overm ultiple genera of bacteria and archaea share a common helix-turn-helix (HTH) structure in their DNA-binding domain. However, TetR proteins can work in different ways: they can bind a target operator directly to exert their effect (e.g. TetR binds Tet(A) gene to repress it in the absence of tetracycline), or they can be involved in complex regulatory cascades in which the TetR protein can either be modulated by another regulator or TetR can trigger the cellular response. TetR regulates the expression of the membrane-associated tetracycline resistance protein, TetA, which exports the tetracycline antibiotic out of the cell before it can attach to the ribosomes and inhibit protein synthesis. TetR blocks transcription from the genes encoding both TetA and TetR in the absence of antibiotic. The C-terminal domain is multi-helical and is interlocked in the homodimer with the helix-turn-helix (HTH) DNA-binding domain. This entry represents the C-terminal domain present in family members such as HTH-type transcriptional repressor KstR2 as well as fatty acid metabolism regulator proteins. In Mycobacterium smegmatis, KstR2 is involved in involved in cholesterol catabolism, while YsiA in Bacillus subtilis is involved in fatty acid degradation.	8.00598e-30

Protein sequences

>CP032698.1|AYG83831.1|6737766_6739014_-|hypothetical-protein
MTLPRRTLLTGALTTGATTTALGTSAPARAAAPTQTRTGFDHLTTTAYTDLTNQKVGLVTNPTGVTRDVRHFVDVMHADPRVHLVAVFGPEHGFRGTAQAGGSQGRYDDPATGLPVYDTYTKSGRALADIFGASGVDTVVFDIQDVGARFYTYIWTLYDCMEAAALAGKRFVVLDRPNPVTGRAAYGPVLDPAFASFVGRVPISQAHGMTAAELARLFNAEFLGGKVRLTTVRMSGWRRSDFFDRTGLPWVPPSPNMPTPDSALVYSGTCLFEGTNLSEGRGTTRSFELLGAEGLDGRWAAALDALALPGVRFREAYFAPTFSKFAGKTVGGVQLHVHERRLFDPVRTGIAALVTAKRVWAGFAWRPDHWVDKLTGSALVRTMIDAGASTDDIVAAWQPGLRAFRALRAEHLLYD
>CP032698.1|AYG83830.1|6736282_6737650_-|hypothetical-protein
MNLFTETLHRSRRSPLSGRGAVLLLLTLCLGLLTTVPPARAAPLPAGPALPSDPVRELARGAVPLSDPRPLGRMTAGADIVGLGEATHNSHEFFATKQRVFQYLVEQRGFTTFALEVSWSSGLRVNDYVRYGKGDPERVVHEEFQGSYTVWDTQEYLDLIRWMRGYNQHHPANQVQFMGDDMGYAGPALFDRVTAYTARHYPKLLPEIDRLYRQSRPTAGVGDTMMSYLRRPMNERQRMAADTARAYALLSAQHPGADAEAFDWVVQDARTIAQTGQQFGYDFDDPEQLRASRGYRDRVMAENTLWWQRHTGHRMLLSAHNGHVGYEPTGDGEYPKMQGAFLREAIGSRYVSIGFTFGQGSFNAFDLTDPAEPIRTFSVPPLGAGSNEEVLERVSPRDFYLDLRAASRPARAWLAVTRPTRSIGNAWPAEVERTRLGASFDILIHLHRVRAADRL
>CP032698.1|AYG83829.1|6734886_6736197_-|hypothetical-protein
MADIGVEPYREITFDADGDADPAERTALTGVDATDLVLFAHGWNNTPDTARGLYRAFFAPFPALLSGTSGVRLGYGGVTWPSIRFTDETIPNFPHATQTDPAPGLDERTVAALKGFFPGQDADVDRIAALLAQRPDAQEAFEEFGLLSRRLVTTGAGRAGAMGDLAAENGQGVSAAILTDDTLTLCQRFTAALADTGMPVEAGPPGPSFSIGGSLKHLWDGAKEVLRQLTYYEMKHRAGTVGQLGLGPLIGQLSLSRPDLRIHLVGHSQGARLVAFALKGLPRGARNVKSVTLLEGAFSHYAFAERLPDGLPGAGALSDAQDRADGPVVSCYSRSDTALGVIYPLASALSGDYASELPGLDRRWWAIGHDGIQAVTPCTTLTLAEALRDGVPDSGCVSVDASSVVKAGGPPSGSHSDICHPELARLVLAAGRIVRI
>CP032698.1|AYG83828.1|6732035_6734870_+|Penicillin-G-acylase
MRRRTARLTTAATTNRLRRVKGIGRGRAAACAATVIALSAALLGPAIPAGAAEPADGDHCQGQCSDILPPGANGNATLVEILGNKLFGTHPAHSDDELGKYDALVAGQSSLTDDKLNAFFNDASFGVPSGQVQSTSSPRPDVTITRDKATGVPHIKGTTRYGTEYGAGYAAGQDRLWLMDLFRHIGRGELTSFAGGALANQGLEQEFWPQAPYTEADLQAQVDRIRTGNGARGEQAMADAQAYVDGINAYAKQSKDGRYFPGEYVLTGKIDSITNVGEIQPFKLTDLIALASVVGGLFGGGGGGEVQAALSLQAAQAKYGVAEGTKVWESFRERDDPEAVLTVHDGTSFPYAGKPANARGTALPDPGSVVPEQLVYDRTGSANTQAKADVKAPPKLAPLKGMYDNGVLPGIDLGKPRGMSNALVVSGSHTASGHPVAVFGPQTGYFAPQLLMLQEIQGPGISARGASFAGVGMYVQLGRGQDYAWSATSAGQDITDTYAVELCQDATHYLYRGTCTPMEKMEKANSWKPTVADTTAAGSYRMQVWRTNYGIVTARATVGGKPVAYTSLRSTYRHDADSIIGFQMMNDPTFVKDAQSFQEAARSVDYTFNWFYADSRTAAYYNSGLNPVRNPDVDPSLPVKAEQAYEWQGFDPTSNTAGYTPPAQHPQSIGQDYYVSWNNKQAKEYSTAGFGDGSVHRANLLDDRVKALVAQGGVTRSSLTRAMAQAAVTDLRGEDVLPELLKVLHSAPVTDPQLATAVQQLDAWKADGTQRRETSQGSHTYTHPDAVRLMDAWWPLLVEAEFRPGLGDPLYNALTTNLGIDEAPSAGHGPTGSHAGSAFQYGWWSYVDKDLRTVLGEPVQGPLGRAFCGDGKPAACRDSLLGTLKQAAAKTPAQVYPGDAGCSAGDQWCADSIVQRPLGGITQSVINWQNRPTYQQVVEFPSHR
>CP032698.1|AYG83827.1|6730883_6731495_-|hypothetical-protein
MAGFRSLARQVRDPRNDLALRRYSLRKCLERFAPYGHRATWDHLCRRHRIGPEDRAPDPARLVAALEELEAARAVWLAYEVEFAARRKREKHAGLRRPGSFDDWHRRTWGGFGVAWCDDPRTHPVEPLAVVLGRMIAALRAQPGTLCPVCRESRLVWSQDLSHEPWFGPVCSGCGILVPQPVLTPEALSRAKAARRGELASVA
>CP032698.1|AYG83826.1|6729998_6730736_-|hypothetical-protein
MSVGSGTLEDMIQVCLNGARGAADGAMVPLSPAALARSAADAVAAGAAEIHVHPKTPCGDDSLSPGVVGPALEAIRAVVSVPVGVTTGAWAEPDPARRVERVKSWTVLPDYASVNWHEEGAEAVAAALLDRGVGIEAGIWSGTDAARRFLASPLGPRVLRVLAEVTDPAQGAAEPTARALLAELGAAHGRPVLLHGEDDHAWPVLRLALALGLDTRVGLEDVLVLPDGQRAASNAQLVSAALGRA
>CP032698.1|AYG83825.1|6729466_6729928_+|Redox-sensitive-transcriptional-activator-SoxR
MPQIPEKIHELTVGQLSARSGAAVSALHFYETKGLIVSRRTSGNQRRYGRDTLRRVAFIRAAQRVGIPLATIRDALAALPEERTPTKEDWALLSENWRAELDRRISQLGRLRDHLSDCIGCGCLSLDTCVLSNPDDVFGTSRTGSRLLAERKA
>CP032698.1|AYG83824.1|6728835_6729336_-|putative-enoyl-CoA-hydratase-1
MTVRASREAGTKDMAEPRIFTSAEELKAGVGEQLGHSDWLEIDQKRIDLFADATGDHQWIHVDPARAATGPFGTTIAHGYLTLSLLPTLVPQVLRVEGMKMGINYGTNKVRFPSPVPVGSRLRATAELTEVVEAGGGVQVTAKVTVEREGGDKPVCVAESVSRYFF
>CP032698.1|AYG83823.1|6728066_6728702_+|Fatty-acid-metabolism-regulator-protein
MGTADVTEETAGGEEKPWGEVTPEAARRLLVAAVEAFAERGYHATTTRDIAGRAGMSPAALYIHYKTKEELLHRISRIGHDKALEILRSAAEGEGSAAERLSAAVRSFVRWHAGHHMTARVVQYELDALGAEHRGEIVELRRQSDAAVRRILGDGVAAGEFDVPDVPGTTLAVLSLCIDVARWFNTEGRRTPDEVGALYADLVLRMVGAQK
>CP032698.1|AYG83822.1|6727695_6727995_+|hypothetical-protein
MLSVMSETPVKQQNTAAYYGQAVAAFSIALVATAIGILRLQADAWVRAFLAMAVLYLVTSAFTLAKVIRDRQEAGQIVSRVDQARLEKLLAEHDPFQKL
>CP032698.1|AYG83832.1|6739841_6740615_+|1-deoxy-11-beta-hydroxypentalenate-dehydrogenase
MSTGQTAEGTTVVVTGAGGGIGAALARRFAAQGARVVVNDLDADKARRTAEEIGAIAVPGDASTVVGAARDALGGTIDVYCANAGLGSGGSESAPEDVWAAAWDVNVMAHVRAARELLPDWLERGRGRFVSTVSAAGLLTMIGAAPYSVTKHGALAFAEWLSLTYRHRGIQVHAICPQGVRTDMLADTGTAGDLVLKPTAIEPDEVADALFAAMAEDRFLVLPHPEVADYYTARAATPDRWLTSMNHLQQKWEASAG
>CP032698.1|AYG83833.1|6740611_6742264_+|Long-chain-fatty-acid--CoA-ligase
MSSIYATKPWLSQLSAAQRADIDPPETVLDSFRAAVARAPEHTALAYFDGRLSYREVDELSDSVAGHLAARGLVRGDRVALMLQNSPHFVIALLGAWKAGATVVPLNPMYKAGEVAHVLHDAEAAALICSDRAWEGYLRDTAADSPVRVALTACELDLQSRDDERVLGFERLPVAADADDLLAVARQGLAAPSGRELGGGDTALISYTSGTSGTPKGAMNTHRGITYQAERQRTGHPIPPGAGYFALAPLFHITGMVCELATCVANAGTLVLTYRFHPGVVLDAFVEHRPAYTVGPSTAFMALAATPGATPEHFASFKLISSGGAPLPPALVEKFREGFGPYIRNGYGLTECTAPCASVPPEKEAPVDPVSGTLSVGVPGPETVVRIVGPEGKEVPFGEQGEIVVRGPQVVPGYWRRPEATVEAFPDGELRTGDIGFMDRDGWLYVVDRMKDMINASGFKVWPREVEDVLYSHPAVREAAVVGIPDSYRGESVKAYVSLRPGAEAGPAELAAYCKERLAAYKYPREVEILAELPKTTSGKILRRELRTQA
>CP032698.1|AYG83834.1|6742403_6743000_+|HTH-type-transcriptional-repressor-KstR2
MAKATDTSGTTPVPQRLLAAATRLFAENGYDRTSVQEIVEAAGVTKGALYHYFGSKEDLLQEVYARVLRLQQERLDAFADADEPIERRLREAAADVVVTTIDNLDDAAIFFRSMHHLSPEKNKQVRAERRRYHERFRALVEEGQNAGVFSTATPADLVVDYHFGSVHHLSTWYRPDGPLTQQQVADHLADLLLRALRP
>CP032698.1|AYG83835.1|6743012_6744227_-|(R)-benzylsuccinyl-CoA-dehydrogenase
MDFAYDARTEELRATLLAFMDEYVHPAEVTAHEQRAQLASPWDTPQVVEDLKAEARRQGLWNLFLPDAEHGAGLTNLQYAPLAEITGRSPHLAPTALNCAAPDTGNMEALAQFGSDEQKKQWLQPLLAGEIRSAFAMTEPEVASSDATNIETRIERDGDDYVITGRKWYISGAMNPDCAIFIVMGKTDPGNADVRRQQSMVLVPRDTPGVEIRRAMQVYGYEDHSHGGHAEVVFHGARVPASNLIGEAGGGFAIAQARLGPGRIHHCMRLIGMAERAIELMCRRAVSRTAFGKPMAQQGVVQEWIADARVAVEQVRLLVLKTAWLMDTVGNRGAHTEIQAIKIATPRTVLDIIDKAIQLHGAGGVSQDFPLAELWASARTLRLADGPDEVHQRSLARRELKKYL
>CP032698.1|AYG83836.1|6744236_6745259_-|Putative-aminoglycoside-phosphotransferase
MSTVPPPGLDPETLRAHLDRVRPGLVSGPLTARLIEGGRSNLTYVVTDGTGQWVVRRPPLGHVLATAHDMRREHRVISALHPTAVPVPEPVLLCEDESVLGSPFYVMEYVTGTPYRTAEQLAPLGPERTRAAVLALVDTLVELHAVDPQAVGLGDFGRPEGFLDRQLRRWGKQLDASRNRDLAGIDELHAALGRALPTSPAPTVIHGDYRLDNVLIGDDERIKAVLDWEMSTLGDPLTDLGLLVMYSAKLELPHSPVSTTAGAAGHPSPAELIERYAARSGRDTSALSWYTAFAWFKLAVILEGIHYRYTLGQTVGAGFDRIGELVPVFIEHGLTTLQEG
>CP032698.1|AYG83837.1|6745437_6745758_-|hypothetical-protein
MPSAVSARDPGLQPERTRLAWRRTTLSCTVAAVLAAKQALRQGSSPLALVAVALSGLVWLGFLAVAHRRIQALSHGVRPRMLGVRSAAAAALCTVALACFALATLF
>CP032698.1|AYG83838.1|6745757_6746150_-|Inner-membrane-protein-YidH
MITIVQTLRLWFAPQRIGEEGETPDYRFSLANERTFLAWIRTSLALVGGGFAVDQFLPDLRWGVRVALALALLAAGVLCALRAVNHWVRCERAMRRGEDLPVSRFPTLLSLAVAVVAVVMVVVVVFGWAG
>CP032698.1|AYG83839.1|6746175_6746691_-|putative-Nudix-hydrolase-YfcD
MNPADEILDIVDENDTVIGQARRAEVYARGLRHRCVFILARDAAGRIFVHRRTPDKLVFPSLYDMFVGGVVGAGESYDDAALREAEEELGVQGLPRPAPLFTFLYENGEQSWWSSVYEVRCEVPVHPQVEEVAWHTFLPLAEVERRIDTWEWVPDGLAAWRRLRASGLGPS
>CP032698.1|AYG83840.1|6746785_6747682_-|hypothetical-protein
MSVLVLVLAVSAACCLGSGFVLQQNAAQHAPISDFLSPRLLLDLVRMPRWLAGIGLMVAGMVLSALALGSGEVSLVEPLVATNLFFAMWLSRLQTRQPLGRQGWAGLALLAGGVTAFIVAGQPHGGVAEAGALRHWLIVGLVVGIALLMAGLAKHDRLSVAAPVLLAVAAGLLYGLQDALTRISGQRLSGGGWSELLTSWQLYGVIALGVTGLVLVQSAFETAPLRMSLPALTAAQPLAGIACGVGFLGDRLRTDTGALAWEAAGLAAIVTGIVLLGLHPAMPSGTASPEESRDLQPH
>CP032698.1|AYG83841.1|6747848_6749504_+|KsdD-like-steroid-dehydrogenase
MAYDADVIVIGAGLAGLVATAELADAGRKVILLDQEPEQSLGGQAHWSFGGLFLVDSPEQRRMRIKDSRALALQDWYGTAGFDRDEDRWPRAWAEAYVDFASGEKRAWLHAQGVRFFPVVGWAERGGYDANGHGNSVPRFHITWGTGPGIVAPFERRVREAAARGLVRFGFRHRVTGLGRSAGVVDTVSGEILEPSGAERGTASTRTVTGSFELTAQAVIVTSGGIGGNHDLVRAQWPQRLGTPPEHLLSGVPAHVDGLMLGITEKAGAHHINRDRMWHYTEGIQNWNPIWARHGIRILPGPSSLWLDARGNRLPVPLFPGFDTLGTLDHIMKTGYGHTWFVLDQKIIGKEFALSGSEQNPDLTGKSVRGVIGRARADVPGPVRAFMDRGADFVVEKDLAALVRGMNALTEEPLLDEAALRREIVARDREIANPFTKDLQVTAIRGARNYLGDKLIRTAAPHRILDPKAGPLIAVKLHILTRKSLGGLETDLSSRVLTATGEPLPGVYAAGEAAGFGGGGVHGYRSLEGTFLGGCLFSGRAAGRAAAKAVS

Crispr_ID: CP032698_90

• CRISPR_ID: CP032698_90
• CRISPR_location: 6763422-6763502
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_90

Consensus_repeat	Method
TCTTGCGCAGTTCCCCGCGCCCCTA	CRISPRCasFinder

spacers of CP032698_90

>90.1|6763447|31|CP032698|CRISPRCasFinder
AACCCTCTCGCCCCTGCGGACCGTCCCCGCT

CRISPR arrays and Neighbor proteins around CP032698_90

CRISPR arrays

The CRISPR arrays of CP032698_90

>merge|CP032698|90|6763422-6763502|CRISPRCasFinder
TCTTGCGCAGTTCCCCGCGCCCCTAAACCCTCTCGCCCCTGCGGACCGTCCCCGCTTCTCGCGCAGTTCCCCGCGCCCCTA

>CP032698|90|65|6763422-6763502|CRISPRCasFinder
TCTTGCGCAGTTCCCCGCGCCCCTA	AACCCTCTCGCCCCTGCGGACCGTCCCCGCT
TCTCGCGCAGTTCCCCGCGCCCCTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG83845.1|6752711_6754118_-|High-affinity-gluconate-transporter	unknown	unknown	gnl|CDD|308194
CP032698.1|AYG83860.1|6770578_6771136_+|Putative-ribosomal-N-acetyltransferase-YdaF	unknown	unknown	gnl|CDD|379112
CP032698.1|AYG83854.1|6763875_6764826_-|hypothetical-protein	unknown	unknown	gnl|CDD|226145
CP032698.1|AYG83844.1|6752016_6752715_+|Formate-dehydrogenase,-nitrate-inducible,-cytochrome-b556(Fdn)-subunit	unknown	unknown	gnl|CDD|225419
CP032698.1|AYG83858.1|6767300_6768827_+|3-oxoacyl-[acyl-carrier-protein]-synthase-2	unknown	unknown	gnl|CDD|238430
CP032698.1|AYG83849.1|6757212_6757920_-|hypothetical-protein	unknown	unknown	gnl|CDD|366102
CP032698.1|AYG83851.1|6759946_6761590_+|N-substituted-formamide-deformylase	unknown	unknown	gnl|CDD|238625
CP032698.1|AYG83846.1|6754129_6754639_-|Gluconokinase	unknown	unknown	gnl|CDD|225804
CP032698.1|AYG83847.1|6754777_6755479_+|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|225097
CP032698.1|AYG83859.1|6768986_6770504_-|hypothetical-protein	unknown	unknown	gnl|CDD|214702
CP032698.1|AYG83856.1|6765139_6766084_-|D-threo-aldose-1-dehydrogenase	unknown	unknown	gnl|CDD|381378
CP032698.1|AYG83855.1|6764822_6765143_-|L-rhamnose-mutarotase	unknown	unknown	gnl|CDD|377501
CP032698.1|AYG83853.1|6762737_6763373_+|Hydroxyacylglutathione-hydrolase-GloC	unknown	unknown	gnl|CDD|293792
CP032698.1|AYG83857.1|6766154_6767039_-|Ribosomal-large-subunit-pseudouridine-synthase-A	unknown	unknown	gnl|CDD|211332
CP032698.1|AYG83862.1|6771463_6771988_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83861.1|6771273_6771480_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG83863.1|6772040_6772811_+|hypothetical-protein	unknown	unknown	gnl|CDD|379262
CP032698.1|AYG83852.1|6761649_6762738_+|S-(hydroxymethyl)mycothiol-dehydrogenase	unknown	unknown	gnl|CDD|132492
CP032698.1|AYG83850.1|6758037_6759543_+|Low-affinity-putrescine-importer-PlaP	unknown	unknown	gnl|CDD|223605
CP032698.1|AYG83848.1|6755702_6757145_+|L-asparagine-permease-2	unknown	unknown	gnl|CDD|185009

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG83845.1|6752711_6754118_-|High-affinity-gluconate-transporter	gnl|CDD|308194	pfam02447, GntP_permease, GntP family permease. This is a family of integral membrane permeases that are involved in gluconate uptake. E. coli contains several members of this family including GntU, a low affinity transporter, and GntT, a high affinity transporter.	2.36018e-136
CP032698.1|AYG83860.1|6770578_6771136_+|Putative-ribosomal-N-acetyltransferase-YdaF	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	3.88347e-18
CP032698.1|AYG83854.1|6763875_6764826_-|hypothetical-protein	gnl|CDD|226145	COG3618, COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only].	5.79135e-65
CP032698.1|AYG83844.1|6752016_6752715_+|Formate-dehydrogenase,-nitrate-inducible,-cytochrome-b556(Fdn)-subunit	gnl|CDD|225419	COG2864, FdnI, Cytochrome b subunit of formate dehydrogenase [Energy production and conversion].	1.63847e-20
CP032698.1|AYG83858.1|6767300_6768827_+|3-oxoacyl-[acyl-carrier-protein]-synthase-2	gnl|CDD|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	0
CP032698.1|AYG83849.1|6757212_6757920_-|hypothetical-protein	gnl|CDD|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	8.74557e-09
CP032698.1|AYG83851.1|6759946_6761590_+|N-substituted-formamide-deformylase	gnl|CDD|238625	cd01300, YtcJ_like, YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling.	2.6966e-156
CP032698.1|AYG83846.1|6754129_6754639_-|Gluconokinase	gnl|CDD|225804	COG3265, GntK, Gluconate kinase [Carbohydrate transport and metabolism].	2.31371e-77
CP032698.1|AYG83847.1|6754777_6755479_+|putative-HTH-type-transcriptional-regulator	gnl|CDD|225097	COG2186, FadR, Transcriptional regulators [Transcription].	1.70405e-42
CP032698.1|AYG83859.1|6768986_6770504_-|hypothetical-protein	gnl|CDD|214702	smart00507, HNHc, HNH nucleases.	5.4722e-05
CP032698.1|AYG83856.1|6765139_6766084_-|D-threo-aldose-1-dehydrogenase	gnl|CDD|381378	cd19152, AKR_AKR15A, AKR15A family of aldo-keto reductase. The AKR15 family includes Microbacterium luteolum pyridoxal 4-dehydrogenase (PLD), Pseudomonas sp. D-threo-aldose 1-dehydrogenase (FDH), and similar proteins. PLD (EC1.1.1.107) catalyzes irreversible oxidation of pyridoxal. FDH(EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose. FDH (EC1.1.1.122), also called (2S,3R)-aldose dehydrogenase, or L-fucose dehydrogenase, catalyzes the oxidation of L-fucose to L-fuconolactone in the presence of NADP(+). It is also active against L-galactose, and to a much lesser degree, D-arabinose.	4.24831e-131
CP032698.1|AYG83855.1|6764822_6765143_-|L-rhamnose-mutarotase	gnl|CDD|377501	pfam05336, rhaM, L-rhamnose mutarotase. This family contains L-rhamnose mutarotase which is a glycosyl hydrolase that converts the monosaccharide L-rhamnopyranose from the alpha to the beta stereoisomer. In Escherichia coli this enzyme is the product of the rhaM gene (also known as yiiL). The tertiary structure has been solved, in complex with L-rhamnose, and the catalytic mechanism determined. His22 is the proton donor. The enzyme naturally exists as a dimer.	2.30236e-22
CP032698.1|AYG83853.1|6762737_6763373_+|Hydroxyacylglutathione-hydrolase-GloC	gnl|CDD|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	2.80451e-52
CP032698.1|AYG83857.1|6766154_6767039_-|Ribosomal-large-subunit-pseudouridine-synthase-A	gnl|CDD|211332	cd02558, PSRA_1, Pseudouridine synthase, a subgroup of the RluA family. This group is comprised of bacterial proteins assigned to the RluA family of pseudouridine synthases. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. The RluA family is comprised of proteins related to Escherichia coli RluA.	4.09245e-124
CP032698.1|AYG83863.1|6772040_6772811_+|hypothetical-protein	gnl|CDD|379262	pfam13560, HTH_31, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	8.7137e-07
CP032698.1|AYG83852.1|6761649_6762738_+|S-(hydroxymethyl)mycothiol-dehydrogenase	gnl|CDD|132492	TIGR03451, S-hydroxymethylmycothiol_dehydrogenase, S-(hydroxymethyl)mycothiol dehydrogenase. Members of this protein family are mycothiol-dependent formaldehyde dehydrogenase (EC 1.2.1.66). This protein is found, so far, only in the Actinobacteria (Mycobacterium sp., Streptomyces sp., Corynebacterium sp., and related species), where mycothione replaces glutathione. [Cellular processes, Detoxification].	0
CP032698.1|AYG83850.1|6758037_6759543_+|Low-affinity-putrescine-importer-PlaP	gnl|CDD|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	3.88393e-26
CP032698.1|AYG83848.1|6755702_6757145_+|L-asparagine-permease-2	gnl|CDD|185009	PRK15049, PRK15049, L-asparagine permease.	0

Protein sequences

>CP032698.1|AYG83853.1|6762737_6763373_+|Hydroxyacylglutathione-hydrolase-GloC
MSVRARIDHLVTSGTFALDGGTWDVDNNVWIVGDDEEAVVIDAAHDAEAILAALGGRTLRAIVCTHAHNDHIDAAPALAEATGAPILLHPADLPLWKLTHPDRLPDGELADGEAVLIADVVLKVLHTPGHAPGAVCLYAPALGTVFTGDTLFAGGPGATGRSFSHFPTIIDSIRERLLTLPGETVVLTGHGGGTTVGAEASGLEGWVARGH
>CP032698.1|AYG83852.1|6761649_6762738_+|S-(hydroxymethyl)mycothiol-dehydrogenase
MAQQVQGVIAPGKNQPLRVETIVVPDPGPGEAVVKIQACGVCHTDLHYKQGAINDDFPFLLGHEASGIVESVGEGVTDVTPGDFVILNWRAVCGSCRACLRGRPQYCFNTHNARQRMTLLDGGAELSPALGIGAFAEKTLVAAGQCTKVDPAVSPAVAGLLGCGVMAGIGAALNTGNVGRGDSVAVIGCGGVGDAAIVGARLAGAARIIAVDIDDRKLATATTMGATHTVNSRSQDAVEAIRELTGGNGADVVIDAVAHPETYKQAFYARDLAGTVVLVGVPTPEMTLELPLLDVFGRGGALKSSWYGDCLPTRDFPMLIDLHQQGRIDLGAFVTETIALDEVEKAFERMQEGNVLRSVVVL
>CP032698.1|AYG83851.1|6759946_6761590_+|N-substituted-formamide-deformylase
MRHAPADLVFTGGPVLTLDAARSRATTVAVTGDRITAVGHDEVRELIGPATEVVDLAGKLLIPGFQDAHVHPVSAGIELARCDLTGLRTATDTVAAVRAYADAHPEQEWITGGGWSMEAFEGGSPTRELLDRVLPDRPVYLPNRDHHGAWVNSRALELAGITRDTPDPADGRIERDTGGEPNGLLQEGAMDLVGRLTPRSTPAERLAALLRAQAHLHAYGITAWQDAIIGGFGSMDDPADAYVAAARDGSLTARVVGALWWDRERGAEQIPELVERRRELSGGRFRAGAVKIMLDGVAETGTAALLGPYLDSCGCATANTGTSFVDPAELRSYVTELDALGFQAHFHALGDRAVREALDAVQAAREKNGWTDTRPHLAHLQIVHPDDIDRFRALGATANIQPLWASHEPQMDELTIPFLGAERAGWQYPFAALLRSGATVAAGSDWPVSSPDPMQGIHTAVNRIAPGEKGPVFLPEQRIGLTAAFAAYTSGTAYVNHLDDTGSIRAGALADLAVLDRDPYAGPAQEIGETRVLATYVGGRRVHDATS
>CP032698.1|AYG83850.1|6758037_6759543_+|Low-affinity-putrescine-importer-PlaP
MRTPYGSDPPPVLRKSLGVVDGVAIAASSTAATTSIGIGLGVTASAVGLHLPIVMLLAFLPILGIASAYTRLNKVEPNMGSGYVWVGRSLSPWLGFLTGWIGIVSTVVFLSYTTAVTGSALLQLAGEAGLDTLGGLRLDPDSTAQSTAIGIVVLIAVTFTAVIGTRSAATLQKWLLVFEYAVLLGFCGYGLIEGPHPFSLDWLNPFTIPSGQALAQGLLLSVFCYWGFESTFSVNEEIKDPEDASRAGLITLFTMLGLFLLGSFAFQRVLSVEELTGHGAQGLTFFGDRLAGQPLAALPLVALTFSAVASLQSGVIPTVRGMFAMSRDRTLGPLWLKVSPRYGTPAAGTVAIGCAAAAIAVLSLLIPKVGDLILASVNAIGIVVSLYYALTALAAASRFRGALRDGVAEGARAVVIPALSALFLLGLGGYLAWTFYASADHFEVSPDNGWFMLLCPAVMVLSGVAAAAWAKWVRKSPYFVPGQPPPESQPAPPPGATPETA
>CP032698.1|AYG83849.1|6757212_6757920_-|hypothetical-protein
MSERVVADGERRRRRPTKGGTVLSEGLIVETALRLIGEHGAAALTVRRLGTALGADPSALYRYFQDTDDLLLAVADELIGRTLRAWRPSGEWRADLRSLGLRIHADYQAHPQAAMLTFTRVTGRVHEMRSVETILGILREAGFPDAEAVRIYHVFVDQTLSFAALDAAVLTLPEESRALEERTWRDRYARLPADTHPHVAATAPTLVAEMGRSAYPAALDMMLAAAAARLRHVRP
>CP032698.1|AYG83848.1|6755702_6757145_+|L-asparagine-permease-2
MPAAEPQSAPAGATPGTPHIDAGDAGYSKDLKSRHINMIAIGGAIGTGLFLGAGGRMAGAGPSLAIAYAVCGVFAFFVVRALGELVLYRPSSGAFVSYAREFMGEKGAYTAGWLYFLNWSTTAVADITAAATYAHFWAMFSDVPQWLCALVALAVVLTANLISVKYFGEMEFWFAIIKVVALVAFMLVGIYLVVTQHDVDGSTPGFANITSHGGIFPMGMLPMLLVIQGVVFAYASVELCGVAAGETENPQKILPKAINSIMWRVGVFYVGSVVLLALLLPYTEYSEGQSPFVTVLDKVGVPGAAGVMNLVVLTAALSSLNSGLYSTGRILRSMSLAGSAPKFVGVMNKGKVPYGGVLFTAFFGVLGVALNGFVPDDAFEIVLNFASIGILGTWAMIMICSLLFWRRAQEGALERPSYRLPWAPYTQIVTLVFLASVAFLMWYGGGVGRTTIYCLPIIAALLVGGWYVVRKRVVALASAK
>CP032698.1|AYG83847.1|6754777_6755479_+|putative-HTH-type-transcriptional-regulator
MTTEARGLHTHVLTSLGLAITAGAYPPGSVLRTDELAQRFDVSRTVVREVVRVLESMHLVESRRRVGVTVRPAEQWNVYDPQVIRWRLAGADRPRQLRSLTVLRSAIEPVAAGLAARLATPAQCADLTEQALGMVATSRGRRLEAYLVHDVAFHRIVLNASGNEMFARLGDVVAEVLAGRTHHQVMFPDPDPAAVTLHVRVAEAIRERDAEKAERLTREIAVGALQELDVLAP
>CP032698.1|AYG83846.1|6754129_6754639_-|Gluconokinase
MNSPLTIVVMGVAGTGKTTIGPLVAERLGVPYAEGDDFHPAANVAKMSAGIPLDDADRWPWLDAIGAWAHGRAGLGGVVSSSALKRSYRDRLRAAAPGVVFLHLTGERGLIERRMAERKGHFMPAALLDSQFATLQPLGPDEAGVAVDVSGTPEDIAQRAAAALRTLTI
>CP032698.1|AYG83845.1|6752711_6754118_-|High-affinity-gluconate-transporter
MTRLSVEFLAADATQPITSAGNAQLGIAVLAGIAVIVLLITRFKLHAFLALTIGSLALGAFAGAPLDKTITSFTSGLGSTVAGVGVLIALGAILGKLLADSGGADQIVDTILAKAGKSGGRAMPWAMVAIASIIGLPLFFEVGIVLLIPVVLLVAKRGNYSLMRIGIPALAGLSVMHGLIPPHPGPLVAIDAIGANLGVTLALGVVVAVPTVIIAGPLFSRYAARWVDIPAPDRMVPARPSEDLQKRPSFGATLATVLLPVVLMLAKALVDIVVDDPKNHLQRVTDVVGSPLIALLAAVLVALFTLGRAAGFTKERISTTVEKSLAPIAGILLIVGAGGGFKQTLIDVGVGRMILDFSKGWAIPSLLLAWLIAVAIRLATGSATVATISAAGLVAPLAADMSTAHTALLVLAVGAGSLFFSHVNDAGFWLVKEYFGMDVGQTVKTWSVMETIISVVALGFVLLLSLVV
>CP032698.1|AYG83844.1|6752016_6752715_+|Formate-dehydrogenase,-nitrate-inducible,-cytochrome-b556(Fdn)-subunit
MTPTPGSAGPTDAKTPPPPELPGTVRRFTPGQRWVHRATAWLMGACVVTAAILYVPQFAEAVGRRELVVRVHEICGALLPLPVLLGVASRAFRADLGRLNRFHPYDRTWLRTALRREREPRPAGKFNAGQKVYAGWIAGAALVMLGTGLLMWFTHLAPIEVRIGSTFVHDWLSLAVGVVVAGHVWMAIGDPEARRGMRTGSVERSWARREHPLWERELAEEPDPAGSGPGRT
>CP032698.1|AYG83854.1|6763875_6764826_-|hypothetical-protein
MNPADAVEARVVPEVLDVVDAHHHVWELGVRDQDWIRGPELAPLRRDFTLDELRGEARAAGVGATVLVQTVTVAEETPELLALADGSDLVAGVVGWTDLTSPGVADELARLRELPGGDRLVGIRHQVQGERDPAWLLRPDVRRGLGAVADAGLVHDLVVLPGQLPSCVRAAALHPELTFVLDHLGKPPIASGALEPWSSDVRALAALPNTVCKLSGMVTEASWTRWRLADLRPYAETVLDAFGAGRVMWGSDWPVCRLAASYAGVLGAGRGLVAGLGVGERGAVFGGTARGVYGLSPPAGFAPPHPSPRPSGGVGG
>CP032698.1|AYG83855.1|6764822_6765143_-|L-rhamnose-mutarotase
MRVALHTRVRPDRIEEYEAAHREVPQELTAAIRAAGVASWTIWRSGAALFHLIECTNYARLLSELSELPVNVAWQLRMGELLDVVHDYAGEGAAEAGLPVVWELGL
>CP032698.1|AYG83856.1|6765139_6766084_-|D-threo-aldose-1-dehydrogenase
MRATSLGASHCPVTALSLGGAALGNLFTPLSDETARGAVDAAWEAGIRSFDTAPHYGLGLSERRMGQALRGRPREAYTLSTKVGRILEPRDGGGDDLAAGFAVPATHRRRWDFSADGVRRSIESSLERLGLDRVDIVYLHDPDDHAEQALREAYPALERLRSEGVVRAIGAGMNRTGLLTRFLRESDVDAVLCAGRYSLLDQEAADELLPEAAARGKSVVVGGVFNSGLLADPRPGATYDYAAAPPELVERALKIKAVCAAHGVPLRAAALAFPLRHPAVAGVLVGARSAAEVTDAAALFEASVPDALWEELGL
>CP032698.1|AYG83857.1|6766154_6767039_-|Ribosomal-large-subunit-pseudouridine-synthase-A
MRLPADPEGAWATIGDHLLGRFAGAIGAERVEAMLREGRFVDSDGALSGAEAYRAGAFVWFHREFAPEVPVPFEVGIVYRDERIVIADKPHFLAVTPRGRHITETAVARLRRDLGLPALQPAHRLDRLTAGLALFVVRPEDRGAYQNLFSGRRVRKEYEAVAAYDPGVELPVTVRSRIVKERGVIAAREEAGEPNAESRIELAERRGTLGRYRLLPTTGRTHQLRVHMHRLGLPILHDPVYPVVLPEPEPELFERPLQLLARALEFTDPVDGRAHRFESRLRLGEWPDPQTSDQ
>CP032698.1|AYG83858.1|6767300_6768827_+|3-oxoacyl-[acyl-carrier-protein]-synthase-2
MSEESVMGGKCCLLTTGELVPGDVIATDPDGPWLVVVRTAPATETRTRLQLRPLTGGPDLERVLPRYERQVVRTTRVDPAEVPDPVRPAAPERRRVVVTGLGAVSPLGGDVPELWHGLLEGRCGISVMEGPGFDGLPVRLAARAAVDPAELLPRPMARRMNRSAQFALVAAREAWLDAGLDPAGTVASGLRPTRTGVSMGTIIGGAPVMVESRLTLIERGPRAVSPYTTPMTVPSASAAQISKDLDIRGEARTFVSACASGTEAIGQAIDAIRAGRVDLVVAGGTEAVITPEILAAFAAMRAVSTRNDQPEHASRPFDDARDGFVLGEGAGILVLEDEEHARARGARIYCEAAGWGLSADAFHMAAPEPSGRGVEAALRSALADAGATPADVAHVNAHATATIDGDRTEALALGRLFGDHTRDIPVTANKGALGHLQGGAGAVEAVAAILTLRDGLIPPTVGCDHPEEGMGLDIVRDTPRPLPPCGDIVLSNSFGFGGHNAVLAFRRA
>CP032698.1|AYG83859.1|6768986_6770504_-|hypothetical-protein
MDDDRQKRGPALRAGADGTAGPARSGSGRPEGGARPRGVALYHDMRVEEDFTKCATRLFSILKSAAATSPGDPRYVYLDIQGHRDADGDYDADAREIMREFLPGFLGPYLTEIDTPLFHAKNPEPQREDIPDVLTIRDPDREHAYDHRELPLRNRDSEPDRRRSRPPVRAIADYLGLDEPICLICWQAPVERAHVVPESLGGSNDVRNFALLCPRHHREAPDVADAEAFWSWVDYACERDGHMKWQGLPPEVLAQAERVGLRIDTRGPVRKSLRHFDRVRDELVRLYGWCPEDFAGGYHWGALMEEFHTVMESATSTHFNVPKKASTEAWAFEVARRRLQKDAGDDAVAGTGHERRAGDGEPSAMSSRPTVELAHLTARKSSAGSGAQSLVDAARRADIAIEAVALVRDLIDSTGVASAEDVLRGVREEVADRTAQLERLATELMGQATCRHCGHSIARIGDAAWRHSAAAPMSRGCRAASFDRNGTWDDSLDRTWKATPPKTYR
>CP032698.1|AYG83860.1|6770578_6771136_+|Putative-ribosomal-N-acetyltransferase-YdaF
MAAMDRPRQLIECGDFVLRRWRGQNDFAPAHQLIEESLDHLRPWESWVARHSAKNTRDFLAASESKWASGEVYNYAIAKDGTLLGMCQTYRGAEPQGRHLGYWLHPAATGRGIATAATAALVKEMFTLPDVEYLEITHDASNASSAAIPRRLGFTEVRREPGSPPTAPSCSGTDVVWRLNRPTPP
>CP032698.1|AYG83861.1|6771273_6771480_+|hypothetical-protein
MREELTRLTGNVGGPNCDDDDCPNVYRTKGGSIVVQGDVSDAFTPPSGEGLVEIPEHILREAVRALGW
>CP032698.1|AYG83862.1|6771463_6771988_+|hypothetical-protein
MLLDGDDWRRFFDAFEREAWRFEAQPTYTMPKEQENVARFLRGEDKPTDHNARWHERVRGYIESGKHIGRVRIVRQPLTDYQRYQFAWGIPGNISAGEDIRILDVTRGDFGLPLSGRDWWMFDDSRIAHLNFRPDGTQMNREAYEGDPAPYREWKRVALEHAVPFEEYVRGLDA
>CP032698.1|AYG83863.1|6772040_6772811_+|hypothetical-protein
MRKRAGRTQVWLAQRCNISQTKLSNIETGRVTPGLVDVELILGALDAPPELLAEVTALARLANTEWQGKRASWRRGLEKRQAELAGLEGEASALRYFLPAMVTGLLATPEYIRASLSNSPVGTTKTVARKLERQAVLYESTKHFTFLLTEQAVRWAVVPPVAMAVQMDRLASISHLPNVRIGVIPTGTVVGRGPMNTFTVYDQRLATVETFTGRIVFQDARDIAEHLEVFRMYERHALFGDEVRALLGRWAADCRA

Crispr_ID: CP032698_91

• CRISPR_ID: CP032698_91
• CRISPR_location: 6963283-6963362
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_91

Consensus_repeat	Method
GCGCAGTTCCCCGCGCCCCTTAA	CRISPRCasFinder

spacers of CP032698_91

>91.1|6963306|34|CP032698|CRISPRCasFinder
CCCGTCTCGATCCTGCGGGCCGTGGTCGCTTCTC

CRISPR arrays and Neighbor proteins around CP032698_91

CRISPR arrays

The CRISPR arrays of CP032698_91

>merge|CP032698|91|6963283-6963362|CRISPRCasFinder
GCGCAGTTCCCCGCGCCCCTTAACCCGTCTCGATCCTGCGGGCCGTGGTCGCTTCTCGCGCAGTTCCTCGCGCCCCTTAA

>CP032698|91|66|6963283-6963362|CRISPRCasFinder
GCGCAGTTCCCCGCGCCCCTTAA	CCCGTCTCGATCCTGCGGGCCGTGGTCGCTTCTC
GCGCAGTTCCTCGCGCCCCTTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG84036.1|6963720_6964341_-|Transcriptional-regulatory-protein-LiaR	unknown	unknown	gnl|CDD|225107
CP032698.1|AYG84043.1|6970457_6971072_+|30S-ribosomal-protein-S4	unknown	unknown	gnl|CDD|235411
CP032698.1|AYG84045.1|6973435_6973876_+|hypothetical-protein	unknown	unknown	gnl|CDD|377605
CP032698.1|AYG84030.1|6954095_6956612_+|Bifunctional-(p)ppGpp-synthase/hydrolase-RelA	unknown	unknown	gnl|CDD|223394
CP032698.1|AYG84029.1|6953349_6953901_+|Adenine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|235028
CP032698.1|AYG84042.1|6969551_6970400_-|hypothetical-protein	unknown	unknown	gnl|CDD|378456
CP032698.1|AYG84034.1|6961228_6961939_+|Hydroxyacylglutathione-hydrolase-GloC	unknown	unknown	gnl|CDD|293792
CP032698.1|AYG84040.1|6967414_6968053_+|hypothetical-protein	unknown	unknown	gnl|CDD|240605
CP032698.1|AYG84039.1|6966396_6967266_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	unknown	unknown	gnl|CDD|224054
CP032698.1|AYG84037.1|6964337_6965597_-|Sensor-histidine-kinase-LiaS	unknown	unknown	gnl|CDD|226951
CP032698.1|AYG84044.1|6971093_6973259_-|Putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|226418
CP032698.1|AYG84033.1|6960323_6961076_-|putative-peptidyl-prolyl-cis-trans-isomerase-B	unknown	unknown	gnl|CDD|223725
CP032698.1|AYG84026.1|6949878_6950352_+|hypothetical-protein	unknown	unknown	gnl|CDD|376903
CP032698.1|AYG84031.1|6957151_6958819_+|hypothetical-protein	unknown	unknown	gnl|CDD|372705
CP032698.1|AYG84038.1|6965554_6966400_-|hypothetical-protein	unknown	unknown	gnl|CDD|366444
CP032698.1|AYG84028.1|6952255_6953353_+|hypothetical-protein	unknown	unknown	gnl|CDD|237275
CP032698.1|AYG84035.1|6961953_6963216_+|Histidine--tRNA-ligase	unknown	unknown	gnl|CDD|234586
CP032698.1|AYG84027.1|6950493_6952254_+|hypothetical-protein	unknown	unknown	gnl|CDD|235615
CP032698.1|AYG84032.1|6958889_6960119_-|hypothetical-protein	unknown	unknown	gnl|CDD|377186
CP032698.1|AYG84041.1|6968113_6969502_+|putative-AAA-domain-containing-protein	unknown	unknown	gnl|CDD|237355

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG84036.1|6963720_6964341_-|Transcriptional-regulatory-protein-LiaR	gnl|CDD|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.73324e-73
CP032698.1|AYG84043.1|6970457_6971072_+|30S-ribosomal-protein-S4	gnl|CDD|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	2.30866e-89
CP032698.1|AYG84045.1|6973435_6973876_+|hypothetical-protein	gnl|CDD|377605	pfam06103, DUF948, Bacterial protein of unknown function (DUF948). This family consists of bacterial sequences several of which are thought to be general stress proteins.	1.43564e-08
CP032698.1|AYG84030.1|6954095_6956612_+|Bifunctional-(p)ppGpp-synthase/hydrolase-RelA	gnl|CDD|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
CP032698.1|AYG84029.1|6953349_6953901_+|Adenine-phosphoribosyltransferase	gnl|CDD|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	2.13889e-86
CP032698.1|AYG84042.1|6969551_6970400_-|hypothetical-protein	gnl|CDD|378456	pfam10615, DUF2470, Protein of unknown function (DUF2470). This family is a putative haem-iron utilisation family, as many members are annotated as being pyridoxamine 5'-phosphate oxidase-related, FMN-binding; however this could not be confirmed.	9.77078e-05
CP032698.1|AYG84034.1|6961228_6961939_+|Hydroxyacylglutathione-hydrolase-GloC	gnl|CDD|293792	cd06262, metallo-hydrolase-like_MBL-fold, mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain. Members of the MBL-fold metallohydrolase superfamily are mainly hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) for which this fold was named perform only a small fraction of the activities included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases which can catalyze the hydrolysis of a wide range of beta-lactam antibiotics, hydroxyacylglutathione hydrolases (also called glyoxalase II) which hydrolyze S-d-lactoylglutathione to d-lactate in the second step of the glycoxlase system, AHL lactonases which catalyze the hydrolysis and opening of the homoserine lactone rings of acyl homoserine lactones (AHLs), persulfide dioxygenase which catalyze the oxidation of glutathione persulfide to glutathione and persulfite in the mitochondria, flavodiiron proteins which catalyze the reduction of oxygen and/or nitric oxide to water or nitrous oxide respectively, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J which has both 5'-3' exoribonucleolytic and endonucleolytic activity and ribonuclease Z which catalyzes the endonucleolytic removal of the 3' extension of the majority of tRNA precursors, cyclic nucleotide phosphodiesterases which decompose cyclic adenosine and guanosine 3', 5'-monophosphate (cAMP and cGMP) respectively, insecticide hydrolases, and proteins required for natural transformation competence. The diversity of biological roles is reflected in variations in the active site metallo-chemistry, for example classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, human persulfide dioxygenase ETHE1 is a mono-iron binding member of the superfamily; Arabidopsis thaliana hydroxyacylglutathione hydrolases incorporates iron, manganese, and zinc in its dinuclear metal binding site, and flavodiiron proteins contains a diiron site.	9.73074e-62
CP032698.1|AYG84040.1|6967414_6968053_+|hypothetical-protein	gnl|CDD|240605	cd12922, VKOR_5, Vitamin K epoxide reductase family in bacteria. This family includes vitamin K epoxide reductase (VKOR) mostly present in actinobacteria. VKOR (also named VKORC1) is an integral membrane protein that catalyzes the reduction of vitamin K 2,3-epoxide and vitamin K to vitamin K hydroquinone, an essential co-factor subsequently used in the gamma-carboxylation of glutamic acid residues in blood coagulation enzymes. All homologs of VKOR contain an active site CXXC motif, which is switched between reduced and disulfide-bonded states during the reaction cycle. In some bacterial homologs, the VKOR domain is fused with domains of the thioredoxin family of oxidoreductases which may function as redox partners in initiating the reduction cascade.	1.78103e-60
CP032698.1|AYG84039.1|6966396_6967266_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA	gnl|CDD|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	5.94599e-94
CP032698.1|AYG84037.1|6964337_6965597_-|Sensor-histidine-kinase-LiaS	gnl|CDD|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	2.29125e-49
CP032698.1|AYG84044.1|6971093_6973259_-|Putative-HTH-type-transcriptional-regulator	gnl|CDD|226418	COG3903, COG3903, Predicted ATPase [General function prediction only].	1.68742e-62
CP032698.1|AYG84033.1|6960323_6961076_-|putative-peptidyl-prolyl-cis-trans-isomerase-B	gnl|CDD|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	3.72174e-38
CP032698.1|AYG84026.1|6949878_6950352_+|hypothetical-protein	gnl|CDD|376903	pfam02699, YajC, Preprotein translocase subunit. See.	1.71843e-24
CP032698.1|AYG84031.1|6957151_6958819_+|hypothetical-protein	gnl|CDD|372705	pfam13751, DDE_Tnp_1_6, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	9.30297e-35
CP032698.1|AYG84038.1|6965554_6966400_-|hypothetical-protein	gnl|CDD|366444	pfam01061, ABC2_membrane, ABC-2 type transporter.	1.73889e-16
CP032698.1|AYG84028.1|6952255_6953353_+|hypothetical-protein	gnl|CDD|237275	PRK13022, secF, protein translocase subunit SecF.	2.103e-103
CP032698.1|AYG84035.1|6961953_6963216_+|Histidine--tRNA-ligase	gnl|CDD|234586	PRK00037, hisS, histidyl-tRNA synthetase; Reviewed.	0
CP032698.1|AYG84027.1|6950493_6952254_+|hypothetical-protein	gnl|CDD|235615	PRK05812, secD, preprotein translocase subunit SecD; Reviewed.	1.70348e-110
CP032698.1|AYG84032.1|6958889_6960119_-|hypothetical-protein	gnl|CDD|377186	pfam03993, DUF349, Domain of Unknown Function (DUF349). This domain is found singly or as up to five tandem repeats in a small set of bacterial proteins. There are two or three alpha-helices, and possibly a beta-strand.	3.83614e-16
CP032698.1|AYG84041.1|6968113_6969502_+|putative-AAA-domain-containing-protein	gnl|CDD|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0

Protein sequences

>CP032698.1|AYG84035.1|6961953_6963216_+|Histidine--tRNA-ligase
MSTFQAPKGTYDLIPPDSARFLAVREAIAAPLKRSGYGYIETPGFENVELFARGVGESTDIVTKEMYAFETKGGDRLALRPEGTASVLRAALEANLHKAGNLPVKLWYSGSYYRYERPQKGRYRHFSQVGAEAIGAEDPALDAELIVLANDAYRSLGLRNFRILLNSLGDKECRPVYRAALQDFLRGLDLDEDTLRRAEINPLRVLDDKREAVQKQLAGAPLLRDYLCDACKAYHEEVRDLLTAQGVAFEDDGRLVRGLDYYTRTTFEFVHDGLGSQSAVGGGGRYDGLSEMIGGPALPSVGWALGVDRTVLALEAEGVTLELPARTSVFAVPLGEEARRVLFAKVMELRRAGIAADFGFGAKGLKGAMKNANRSGARFTLVAGERDLAEGVAQLKDMESGEQVPVGLDGVVDAVRERLA
>CP032698.1|AYG84034.1|6961228_6961939_+|Hydroxyacylglutathione-hydrolase-GloC
MLIAGFPAGAWGTNCYLVAPAAGEECVIIDPGHQATQGVEETLKKHRLKPVAVVLTHGHIDHCASVVPVCGAHDVPAWVHPEDRYMMSDPEKAIGRAFGAQLMGDLTVGEPDDVKELTDGAKLTLAGMELIVSHAPGHTRGSVTFGLPEAEDIPPILFSGDLLFAGSVGRTDLPGGSHAELLESLGRVCLPLDDSTVVLSGHGSQTTIGQERATNPYLRQVAAGQGEHTASPRRGM
>CP032698.1|AYG84033.1|6960323_6961076_-|putative-peptidyl-prolyl-cis-trans-isomerase-B
MVSSEQRRRQLAREKFERQQQRREAARRKARRRNTIIAATLAVVVAAGGVAFATGAFSGDGKKSDSAADPSSEPKMTVDAKAKYAMALKTNAGDIKITMDAAKTPHTVNSFKYLADKKYFDNTKCHRLTTQNIYVLQCGDPKGTGSGGPGYTIPDEDLTSLGKAGADSTVTYRAGTVAMANTGQPHTGGSQFFLVYKDTKLPPSYTPFGTMDAAGLKAVQDVAKEGVEGGATDGAPKKAVTIQKAAVTKE
>CP032698.1|AYG84032.1|6958889_6960119_-|hypothetical-protein
MSSDPWGRVDETGTVYVRTAEGEVVVGSWQAGSPEEALAYFERKYEGLVVEIGLLERRVRTTDLSAKDAQAAIDHLRAQVDEHHAVGDLDALRGRLDKLVATVESRREERKVQKAKQTDEAKHAKEALVAEAEELAQSEQWRSAGERLRALVDTWKGLPRLDRKSDDELWHRFSHARSAFSKRRQAHFASLDAQREDARKVKEKLVVEAEALSGSTDWGTTAARYRDLMAEWKAAGRAQREAEDELWNRFRGAQDVFFAARSEVFAERDAEQTENLKLKEELAVEAEKILPVTDLKAARAAFRAVNERWEAIGHVPRDARPKVEGRMHAVERAIQEAEETEWRRTNPEARARAAGLTGQLQDAVDKLHRQIDAARAAGNDSKADKLARELEGRQALLDQALKGLEEFGG
>CP032698.1|AYG84031.1|6957151_6958819_+|hypothetical-protein
MSMQPMESGEIPAETVRVAWAAFPKGSLAIRVRDELGPLFRDEEFADLFPARGKPAWSPGRLALVLVLQFVEGLTDRQAAEAVRARIDFKYALALELSDPGFDFSVLSEFRDRLVKAEAGRRVLDSILAAAGESGLLKTAGRARTDSTHVQSAARQLCWLEQVAETLRAALNEIAQAAPDWLLTVAEPDWFKHYATRAEDSRFPKSRAKRDELGLRIGRDGTRLLEAVFSPGAPGEPRALEQVETLRQVWVQHFQQVEGEVRRRDPKDRPPGATRLVTPYDTEARGSVKRDTMWDGYKVHLTETCEPDIPNLITNVATTVATVPDISMTDIVHAQFAQDGRLPGEHLVDAGYVDAHLLVQARREYGITLTGPVAGVVSHQTTANSGFTGDDFTIDWDHEQVTCPGGETTTRWNPDRSPEGTPVIRVRFNGGQCRPCPVREQCTTSSAGRRLTLRPREEHQALRQARAEQDTDTWKDRYKTRAGVEGTISQAVQRCGLRRSRYRGLAKTSLQHQLTGAAINLARIDAHLTDTPRARTRTSYFAALRPAELMLGGAK
>CP032698.1|AYG84030.1|6954095_6956612_+|Bifunctional-(p)ppGpp-synthase/hydrolase-RelA
MPDEAQPLSAAQPDPQAAEAAAAPATPSEPPATPSEPSPEPKPAAPESGQTPAKAPAPAPVAKPVVPAGSVSRSGGSSNRVRARLARLGVQRSSAYNPVLEPLLRIVRSNDPKIETATLRQVERAYQVAERWHRGQKRKSGDPYITHPLAVTTILAELGMDPATLMAGLLHDTVEDTEYGLDTLRRDFGDQVALLVDGVTKLDRVQFGDAAQAETVRKMVVAMAKDPRVLVIKLADRLHNMRTMRYLKREKQEKKARETLEIYAPLAHRLGMNTIKWELEDLAFAILYPKMYDEIVRLVAERAPKRDEYLAIVTDEVQSDLRAARIKATVTGRPKHYYSVYQKMIVRGRDFAEIYDLVGIRVLVDTVRDCYAALGTVHARWNPVPGRFKDYIAMPKFNMYQSLHTTVIGPNGKPVELQIRTFDMHRRAEYGIAAHWKYKQEAVAGASKVRTDVPRKTGKDDHLNDMAWLRQLLDWQKETEDPSEFLESLRFDLSRNEVFVFTPKGDVIALPAGSTPVDFSYAVHTEVGHRTIGARVNGRLVPLESTLDNGDLVEVFTSKAAGAGPSRDWLGFVKSPRARNKIRGWFSKERRDEAIEQGKDAIARAMRKQNLPIQRILTGDSLVTLAHEMRYPDISSLYAAIGEGHVAAQGVVQKLVQALGGEEAANEDIAESAPPSRGRSKRRKNADPGVVVKGVDDVWVKLARCCTPVPGDPIIGFVTRGSGVSVHRADCVNVDSLSQQPERILEVEWAPTQSSVFLVAIQVEALDRSRLLSDVTRVLSDQHVNILSAAVQTSRDRVATSRFTFEMGDPKHLGHVLKAVRGVEGVYDVYRVTSARRP
>CP032698.1|AYG84029.1|6953349_6953901_+|Adenine-phosphoribosyltransferase
MTSVSTETVGLLLSRIRDVPDYPKPGVLFKDITPLLADPRAFTALTDALAALCVQHGATKIVGLEARGFILAAPVSVRAGIGFIPVRKAGKLPGATLKQAYELEYGTAEIEVHAEDLGAGDRVLVIDDVLATGGTAGACLELIRRAGAEVAGVAVLMELGFLGGRERLEPALRGAPLDALITV
>CP032698.1|AYG84028.1|6952255_6953353_+|hypothetical-protein
MSKLGTLGARLYRGEVGYDFVGKRKIWYGISILITITAIVGLAVRGLTMGIEFEGGAAFTTPKTSMSAAQAESAAEAASGHDAIAQKLGDGTIRITIGGIDTGKSDQIKKELAKDLKVDANTINADLVGPSWGETIAKKAWTGLIVFMILVVIYLAIAFEWRMALAALVALIHDLTITVGIYALVGFEVTPGTVIGLLTILGYSLYDTVVVFDGLKEGQKGITKQTRVTYSEMANKSLNGTLVRSINTTVVALLPVAGLLFIGGGVLGAGMLNDISLSLFVGLAAGAYSSIFIATPLVADLKETMPEMKALKKRVLAKRAAAAAKGETEEPQDDSPLDEDDDPQTAGAVVGQRRQPSRNNRGKRR
>CP032698.1|AYG84027.1|6950493_6952254_+|hypothetical-protein
MAAPNKGRRPAAGGQSKPGRALAFILIAMVALTGGMFLSHTTTPRLGIDLAGGTSITLKAKAEPGQESAINKKNMDTAVQIMNRRVNGLGVSEAEVQTQGSDNIIVNIPKGTNSEQARQQVGQTAKLYFRPVLTAQPTAAPPTPSASPSPSGEATPTPSGKASPNASGKATPSAGKPSSAGTPQGRALTDALKAPGTPTPGASKPSTPAPNPSASGDSAAAAKLQAQFAALDCSTKEARSKAAEGAKSSEPTVACDKDGQEKYILGPAEVDGTDVSKAQAVINQQNGQWIVQMDFTGGGSKKFAAITGKLSQQQYPNNRFAIALDNQVVSAPTVSSTLSGSAEISGNFTQASAQDLANVLSYGALPLSFQEQGVTTVTAALGADQLHAGLIAGAIGLALVIIYLVAYYRGLATIAILSLVVSAILTYAIMTLLGPTISFALNLPAVCGAIVAIGITADSFIVYFERIRDEIREGRTLRPAVERAWPRARRTILVSDFVSFLAAAVLFVVTVGKVQGFAFTLGLTTLLDVVVVFLFTKPVMTLLARRPFFANGHPWSGLDPKRLGAKPPLRRARRTTSAPVDNPKEA
>CP032698.1|AYG84026.1|6949878_6950352_+|hypothetical-protein
MSPITLLPFIVLIGAMFLMTRSAKKKQQAAAAMRNEMQPGTGVRTIGGMYATVKEIGDETVLLEVAPGVHAVYAKNAIGAVLSDEEYNRIVHGDTEEQLPAVPDDASSLTESTEAAEADAAVAEDAKIDLGKKDEAEDAAAPKDGKDGKADGGADTK
>CP032698.1|AYG84036.1|6963720_6964341_-|Transcriptional-regulatory-protein-LiaR
MIRILLADDHPVVREGLRGMLAAEPDLEVVADASNGPQAEALCAELEPDIVLMDLRMPGGDGVESIGRLTASGLPCRVIVLTTYETDRDILRAVEAGAAGYLLKDLARGELAQAVRAAARGETVLAPSVAARLVDQLRARPERPRLSDREVSVLRLVAEGCTNAEIGRRLFVAESTVKTHVVRIFGKLGVDDRTAAVTRAMSLGLL
>CP032698.1|AYG84037.1|6964337_6965597_-|Sensor-histidine-kinase-LiaS
MSGDLQVEEPSRRLTEFAAAAGARDTHVWDRSFLPWDAYFAVVWLATAVFVLGADLPALRYRITAVALMSLLIPWYLRAGRPAMLDDGADERRSLRYVVASVVIFLPPAFLVGETRLITFALAPPCFMLLPLRRAMVTMAIVNVVPVAGWALIWRPPAQAVFFNAVFAVATLAFSGFFGAWVIRIIEQSKERACLIDELERSREEVARLSAERGALTERERMSREIHDTLAQGFTSVLMLVQAVQSELDHDVALARRHLDLMESTARQNLAEARALVAGGAPADLDGGSLPDAVRRLAARHEPPARLEVTGPVRELPAPLEVVALRSCQEALSNARKHAGPGAPVRLSLAYGEAGLTVSIRDEGAGFDLSAPRTGYGLAGLRARAAEVGGTAEVLSAPGAGTTVGVHLPVPAPPLRSPS
>CP032698.1|AYG84038.1|6965554_6966400_-|hypothetical-protein
MTTADTLAPTRAGGPELPGAWSLGLRRGALEIRQFVRQRDQVIFTFAFPVVFLALFASIFSGQVENAGITASQLYAAGMIAAGIMSVSFQSLGISIAIERDEKVLRRLRGTPMPPAAYFLGKVWLVLATGVAETGVLLLFGSTLFDLDLPTTAAKWFDFSWIFVLGITGCALLGIAISSLPRSGKSASSVVVLPFLVLQFISGVYIPVGTVPDWLLNISAFFPLKWMCQGFRGVFLPESASVLEQAGSWEFGRIALVLGAWCIGGLVLCLVTFRWKSRRDG
>CP032698.1|AYG84039.1|6966396_6967266_-|Daunorubicin/doxorubicin-resistance-ATP-binding-protein-DrrA
MTALAVDVRGLRKRYGGVTAVDGVDLRIRHGEVFGILGPNGAGKSTTVEILQGHRDRDGGEVTVLGADPATAGRAWRSRVGIVWQDESAPAELTVRETVDHFARYYPNPRDPEEVIALVGLEGKASARIKGLSGGQRRRLDVALGVIGGPELLLLDEPTTGFDPAARRQFWELIRRLATEGTTIVLTTHYLEEAEALADRLAVIAGGRVVAEGEPAALRQSLGTGATVEWVEPDGAPRSVRTETPTRTVAELMHRFDGEIPGLRIGRPTLEDVYLRLTGRLDPQQEEAR
>CP032698.1|AYG84040.1|6967414_6968053_+|hypothetical-protein
MTTTLDDVSSDSGHREVSGKGAIGGSRAFAWLLVITGAAGVVAAWVITLDKFKLLENPNFVPGCSLNPVVSCGNIMKSDQAAAFGFPNPMLGLVAYGIVVCVGMSILAGARFRRWYWLTFNAGTLFGVGFVSWLQFESLYRINSLCLWCCLAWVATILMFWYVTSFNLRKGLLPAPRWAKNLLSEFTWVLPVLHIGVIGMLILTRWWDFWTS
>CP032698.1|AYG84041.1|6968113_6969502_+|putative-AAA-domain-containing-protein
MLSVACPRLDDVEPDLFTAAAEDRQEKDPAGSPLAVRMRPRVLDEVVGQQHLLKQGSPLRRLVGEGAGGPAGPSSVILWGPPGTGKTTLAYVVSKATNKRFVELSAITAGVKEVRAVIDGARRAIGGFGKETVLFLDEIHRFSKAQQDSLLPAVENRWVTLIAATTENPYFSVISPLLSRSLLLTLEPLTDDDLRALVRRALTEERGLGSAVTLPEDAEAHLLRIAGGDARRALTALEAAAGSALAKSEQEITLQTLEETVDRAAVTYDKGGDQHYDVASALIKSIRGSDVDAALHYLARMIEAGEDPRFIARRLIISASEDIGLADPTALPTAVAAAQAVALIGFPEAALTLSHATIALALAPKSNSATTAIGAAMADVRAGLAGPVPPHLRDGHYKGAAKLGHAQGYVYPHDVPGAIASQQYAPDAVADKRYYEPTRYGAEARYADVVEKVRERLSREGD
>CP032698.1|AYG84042.1|6969551_6970400_-|hypothetical-protein
MSRPGNTSHITDSTKKVGQTPLSREADSPDSSGAGHVTEVRSDRGQPRPSGLEIARMPSAAERTRTLVHSTCSAVLLLPGPGGGRPEQLLTGERGVGPDGDLFLVLPANSPAAGAAGRAQDDAVPAVLELTDVAPVSVPHRIRGRAWVSGRLTPVPGQAGPGQVMLRLAVDEASVDDLWGAATVGRGDFARAAPDPLVRYETELLQHLASAHGEQLGLLCGLVEREGVARVTPLALDRFGLRVRFGRSDGHTFDARFDFPEPVADITALRRAMRRLFEAADG
>CP032698.1|AYG84043.1|6970457_6971072_+|30S-ribosomal-protein-S4
MPNQSRPKVKKSRALGIALTPKAVKYFEARPYPPGEHGRGRKQNSDYKVRLLEKQRLRAQYDISERQMARAYDRAKKAEGKTGEALVVELERRLDALVLRSGIARTIYQARQMVVHGHIQVNGAKVDKPSFRVRPDDVVTVRERSREKVPFQVAREGGYAGEGETPRYLQVNLKALAFRLDRDPNRKEIPVICDEQLVVEYYAR
>CP032698.1|AYG84044.1|6971093_6973259_-|Putative-HTH-type-transcriptional-regulator
MRSHLPAELNRFVGRDRELARVDRLLLDARLVTVTGVGGVGKTRLALRAAATTAEQERYCDGVRLVELSSLTDPALLDHAVVEALGLTDHTARPPRRLLLDHLAERELLLVLDGFEQVVVDCAELVRELLRGCPRLRVLAAGRLPLRIDGERVFTLAPMNERDALALFAERAAESRGAERPSEGDGPAAAELCRRLDGIPLALELAAGRLGTLSVEQLLRRLDDRFRLLTGGGRGALPRHQTLRTTIGWSHELCTGAQRLLWARLSVFAGAFDLEAVEYICVGPDLPQQDVLDVLGELLDQSVVVREDGAGGLRYRLLDTVREYGAEWLAATGDAERLHRRHRDWYLGLATWCELDWFSPRQAEVAARVEAELPNVRAAMEFSLASPEDTHLAQYLAGTLWFYWAGCGRLAEGRHWLTQVLDAESEHDSSRLKALWVLGYVAVLQGDAVAAIAALQECREEAESRADAVAVAYAVHRCGCLALVTDDMPRAEELLREALAGYEEVGELNSNVLMGRVEMAMAVGFRGRLDEAVAICEHVVEVCDEHGERWARAYALYVLAYAAWYGGDPVRARTLLRETLAVSHTFHDLVGTVLTLEMLALVEVDAGDPAEAAVLQGAAERIWPSVGLPLFGSAYFYAAHVLCEERTRERLGDAAYEKHRRRGARIETDAAVARALAGGQEADGVRELPPAREGQQPEGPGHAEARRLPLRAERGDGGLKR
>CP032698.1|AYG84045.1|6973435_6973876_+|hypothetical-protein
MSGGEVAGILVAVFWAILVSFLAVVLVRLAQTLRATTKLVAEVTDQAVPLLADASLAVRSAQTQLDRVDAIASDVQEVTANASALSTTVASTFGGPLVKVAAFGYGVRRAMGRKSAAPADVPAKSARRTVIVGRTVPPARRSKRKG

Crispr_ID: CP032698_92

• CRISPR_ID: CP032698_92
• CRISPR_location: 7020458-7020561
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_92

Consensus_repeat	Method
CCCTGGGGCTTCGCCCCAGACCCCG	CRISPRCasFinder

spacers of CP032698_92

>92.1|7020483|54|CP032698|CRISPRCasFinder
AGCCCCTTTGCCCGCCCACCCGCCCGTAGGCGCAGGGTTGGACGGCTCCGGGCT

CRISPR arrays and Neighbor proteins around CP032698_92

CRISPR arrays

The CRISPR arrays of CP032698_92

>merge|CP032698|92|7020458-7020561|CRISPRCasFinder
CCCTGGGGCTTCGCCCCAGACCCCGAGCCCCTTTGCCCGCCCACCCGCCCGTAGGCGCAGGGTTGGACGGCTCCGGGCTCCCTGGGGCTCCGCCCCAGACCCCG

>CP032698|92|67|7020458-7020561|CRISPRCasFinder
CCCTGGGGCTTCGCCCCAGACCCCG	AGCCCCTTTGCCCGCCCACCCGCCCGTAGGCGCAGGGTTGGACGGCTCCGGGCT
CCCTGGGGCTCCGCCCCAGACCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG84092.1|7026537_7027815_+|hypothetical-protein	unknown	unknown	gnl|CDD|377511
CP032698.1|AYG84096.1|7033400_7034489_+|Riboflavin-biosynthesis-protein-RibD	unknown	unknown	gnl|CDD|273015
CP032698.1|AYG84093.1|7027861_7029064_-|Inner-membrane-protein-YbjJ	unknown	unknown	gnl|CDD|340951
CP032698.1|AYG84083.1|7015145_7015490_+|hypothetical-protein	unknown	unknown	gnl|CDD|376530
CP032698.1|AYG84097.1|7034491_7035100_+|Riboflavin-synthase	unknown	unknown	gnl|CDD|236455
CP032698.1|AYG84079.1|7010622_7011711_-|hypothetical-protein	unknown	unknown	gnl|CDD|368185
CP032698.1|AYG84088.1|7021229_7022027_+|(R)-stereoselective-amidase	unknown	unknown	gnl|CDD|143600
CP032698.1|AYG84082.1|7014726_7015149_+|Guanyl-specific-ribonuclease-St	unknown	unknown	gnl|CDD|238340
CP032698.1|AYG84087.1|7019977_7020433_+|Regulatory-protein-AsnC	unknown	unknown	gnl|CDD|224439
CP032698.1|AYG84090.1|7023918_7024683_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84095.1|7030441_7032805_-|Chitodextrinase	unknown	unknown	gnl|CDD|225862
CP032698.1|AYG84086.1|7018497_7019967_+|putative-amino-acid-permease-YhdG	unknown	unknown	gnl|CDD|129987
CP032698.1|AYG84080.1|7011711_7013061_-|Glutamine-synthetase	unknown	unknown	gnl|CDD|223252
CP032698.1|AYG84081.1|7013083_7014655_-|DNA-ligase-B	unknown	unknown	gnl|CDD|235108
CP032698.1|AYG84078.1|7009558_7010584_+|Sorbitol-operon-regulator	unknown	unknown	gnl|CDD|367868
CP032698.1|AYG84084.1|7015579_7017061_+|putative-oxidoreductase	unknown	unknown	gnl|CDD|181127
CP032698.1|AYG84094.1|7029135_7030326_+|N-acetylglucosamine-repressor	unknown	unknown	gnl|CDD|224851
CP032698.1|AYG84085.1|7017057_7018137_-|hypothetical-protein	unknown	unknown	gnl|CDD|238881
CP032698.1|AYG84089.1|7022174_7023866_+|Tryptophan-2-monooxygenase	unknown	unknown	gnl|CDD|366721
CP032698.1|AYG84091.1|7024880_7026260_-|Putative-pyrimidine-permease-RutG	unknown	unknown	gnl|CDD|132655

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG84092.1|7026537_7027815_+|hypothetical-protein	gnl|CDD|377511	pfam05426, Alginate_lyase, Alginate lyase. This family contains several bacterial alginate lyase proteins. Alginate is a family of 1-4-linked copolymers of beta -D-mannuronic acid (M) and alpha -L-guluronic acid (G). It is produced by brown algae and by some bacteria belonging to the genera Azotobacter and Pseudomonas. Alginate lyases catalyze the depolymerization of alginates by beta -elimination, generating a molecule containing 4-deoxy-L-erythro-hex-4-enepyranosyluronate at the nonreducing end. This family adopts an all alpha fold.	1.6601e-86
CP032698.1|AYG84096.1|7033400_7034489_+|Riboflavin-biosynthesis-protein-RibD	gnl|CDD|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	2.12676e-120
CP032698.1|AYG84093.1|7027861_7029064_-|Inner-membrane-protein-YbjJ	gnl|CDD|340951	cd17393, MFS_MosC_like, Membrane protein MosC and similar proteins of the Major Facilitator Superfamily of transporters. The gene encoding Sinorhizobium meliloti membrane protein MosC is part of the mos locus, which encodes the biosynthesis of the rhizopine 3-O-methyl-scyllo-inosamine. MosC belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.97127e-88
CP032698.1|AYG84083.1|7015145_7015490_+|hypothetical-protein	gnl|CDD|376530	pfam01337, Barstar, Barstar (barnase inhibitor).	4.83761e-25
CP032698.1|AYG84097.1|7034491_7035100_+|Riboflavin-synthase	gnl|CDD|236455	PRK09289, PRK09289, riboflavin synthase.	5.04147e-112
CP032698.1|AYG84079.1|7010622_7011711_-|hypothetical-protein	gnl|CDD|368185	pfam04909, Amidohydro_2, Amidohydrolase. These proteins are amidohydrolases that are related to pfam01979.	5.82257e-07
CP032698.1|AYG84088.1|7021229_7022027_+|(R)-stereoselective-amidase	gnl|CDD|143600	cd07576, R-amidase_like, Pseudomonas sp. MCI3434 R-amidase and related proteins (putative class 13 nitrilases). Pseudomonas sp. MCI3434 R-amidase hydrolyzes (R,S)-piperazine-2-tert-butylcarboxamide to form (R)-piperazine-2-carboxylic acid. It does so with strict R-stereoselectively. Its preferred substrates are carboxamide compounds which have the amino or imino group connected to their beta- or gamma-carbon. This subgroup belongs to a larger nitrilase superfamily comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13), class 13 represents proteins that at the time were difficult to place in a distinct similarity group. It has been suggested that this subgroup represents a new class. Members of the nitrilase superfamily generally form homomeric complexes, the basic building block of which is a homodimer. Native R-amidase however appears to be a monomer.	1.27497e-131
CP032698.1|AYG84082.1|7014726_7015149_+|Guanyl-specific-ribonuclease-St	gnl|CDD|238340	cd00607, RNase_Sa, RNase_Sa. Ribonucleases first isolated from Streptomyces aureofaciens. In general, ribonucleases cleave phosphodiester bonds in RNA and are essential for both non-specific RNA degradation and for numerous forms of RNA processing. RNAse Sa is a guanylate specific endoribonuclease which belongs to the superfamily of microbial ribonucleases. Typical of this sub-family, the enzyme hydrolyses the phosphodiester bonds of RNA at the 3' oxygen end of guanosine residues to yield oligonucleotides with the guanosine-2',3'-cyclophosphate at the 3' end and the hydroxyl group at the 5' end. The terminal guanosine-2,3'-cyclophosphate is hydrolysed by guanyl RNAses to give guanosine-3'-phosphate.	5.32331e-44
CP032698.1|AYG84087.1|7019977_7020433_+|Regulatory-protein-AsnC	gnl|CDD|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	2.47047e-29
CP032698.1|AYG84095.1|7030441_7032805_-|Chitodextrinase	gnl|CDD|225862	COG3325, ChiA, Chitinase [Carbohydrate transport and metabolism].	1.88499e-140
CP032698.1|AYG84086.1|7018497_7019967_+|putative-amino-acid-permease-YhdG	gnl|CDD|129987	TIGR00909, putative_amino_acid_transporter, amino acid transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.35622e-175
CP032698.1|AYG84080.1|7011711_7013061_-|Glutamine-synthetase	gnl|CDD|223252	COG0174, GlnA, Glutamine synthetase [Amino acid transport and metabolism].	2.16109e-89
CP032698.1|AYG84081.1|7013083_7014655_-|DNA-ligase-B	gnl|CDD|235108	PRK03180, ligB, ATP-dependent DNA ligase; Reviewed.	0
CP032698.1|AYG84078.1|7009558_7010584_+|Sorbitol-operon-regulator	gnl|CDD|367868	pfam04198, Sugar-bind, Putative sugar-binding domain. This probable domain is found in bacterial transcriptional regulators such as DeoR and SorC. These proteins have an amino-terminal helix-turn-helix pfam00325 that binds to DNA. This domain is probably the ligand regulator binding region. SorC is regulated by sorbose and other members of this family are likely to be regulated by other sugar substrates.	7.72059e-75
CP032698.1|AYG84084.1|7015579_7017061_+|putative-oxidoreductase	gnl|CDD|181127	PRK07807, PRK07807, GuaB1 family IMP dehydrogenase-related protein.	0
CP032698.1|AYG84094.1|7029135_7030326_+|N-acetylglucosamine-repressor	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.00292e-34
CP032698.1|AYG84085.1|7017057_7018137_-|hypothetical-protein	gnl|CDD|238881	cd01844, SGNH_hydrolase_like_6, SGNH_hydrolase subfamily. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.	2.02847e-49
CP032698.1|AYG84089.1|7022174_7023866_+|Tryptophan-2-monooxygenase	gnl|CDD|366721	pfam01593, Amino_oxidase, Flavin containing amine oxidoreductase. This family consists of various amine oxidases, including maze polyamine oxidase (PAO) and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.	9.29687e-49
CP032698.1|AYG84091.1|7024880_7026260_-|Putative-pyrimidine-permease-RutG	gnl|CDD|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	1.5826e-105

Protein sequences

>CP032698.1|AYG84087.1|7019977_7020433_+|Regulatory-protein-AsnC
MRLNDLDERIVHALAEDARRSYADIGSLIGLSAPAVKRRVDRLRAEGAITGFTVRVDPAALGWETEGFIEIYCRRNTSPDAIRRGLERYPEVASASTVTGEADAIIQVFASDMRHFERVLERIAGEPYVERTKSVLVLSPLLRRYTSGSPA
>CP032698.1|AYG84086.1|7018497_7019967_+|putative-amino-acid-permease-YhdG
MLDHGAAPPSTEPPAAGGPRPGSGLMRRKPVETLVAEGGQGEGGSLKRSLGMWQLTMISIGATLGTGIFVVLGEAVPKAGPAVTLSFVLAGLTALFSALSYAELAGSIPVAGSSYSYAYATLGELIAWICGWCLILEYGVSVAAVAVGWGQYLNEFLDGTIGVTIPDALSAPPGDGGIFNLPALIVVVLAMGLLLGGARESARINTIMVAVKIAALVLFCVIGFMGFKSGNYSNFMPLGTAGVSGAASTLFFSYIGFDAASTAGEEAKNPKKDLPRAIMLSLIIVTALYVLVAFVAVGARPWKQFEGSEAALAGIMKDVTGHSFWGTLLAACAVIAIASVVLTVLYGQTRILFAMSRDGLVPKVFAKVSPRSGTPVANTVAVSLFCGVLAAAVPLGNLADATSIGTLFAFALVNVAVIILRRTRPDMPRTFRVPFGWLVPILGFLSCGYLMWNLSGVTWEYFGYWMAAGLVIYFGYGYRRSRLATASQK
>CP032698.1|AYG84085.1|7017057_7018137_-|hypothetical-protein
MDLDTPHEIAGEPATGWQDPAPFLRGVAWLDAEGQPVRADPEDAMRLPWDTGERAALPIGMRIEFTARGATAVEIRYRARVPEPGEALHELAHTFALWQGDRCLGETTATPHREGRVRIQLPCSAGPFTIHPPETQAPHIDAVRAVGGMIAPTRRTARWLVHGDSITEGWWSTRPAHAWPAVVGRTLGLDTVNLGYAGGGRGELPTAEQIARLPADVLTLAFGTNCWSAIPFSAPLMRETTLAFLRLVRRGHRKTPLLLVSPLLRPEAERTPNALGATLAELRAAMESATRELIDAGDDALQLLSGQGLLEPHHLMDGLHPTDEGHARVAAAVARALAPLVPKPPRADSRGLGAEQQGD
>CP032698.1|AYG84084.1|7015579_7017061_+|putative-oxidoreductase
MPGATSIDWDVQHVRFLNDIKPPYDLTYDDVFMVPSRSAVGSRQGVDLASPDGTGTTIPLVVANMTAIAGRRMAETVARRGGIVVIPQDIPIEVVTDVISWVKTRHLVLDTPIVLAPSQTVADALALLPKRAHNAGVVVDADQKPIGVVTDQDLTGVDRFTRLSEVMSKDLLLLDADIDPREAFNRLDNANRRYAPAVDADGRLAGILTRKGALRATLYTPATDARGKLRIAAAVGINGDVAGKAKQLLDAGADTLVVDTAHGHQESMIAAIKAVRGLDPHVPIVAGNIVAAEGVRDLIEAGADIIKVGVGPGAMCTTRMMTGVGRPQFSAVLECAAEAKKFGKHVWADGGVRHPRDVAMALAAGASNVMIGSWFAGTYESPGDLHTSAEGHLYKESFGMASARAVKNRTSEESAYDRARKALFEEGISTSRMFLDPTRPGVEDLIDSIIAGVRSSCTYAGASSLAEFEEKAVVGIQSAAGYAEGKPLHASWS
>CP032698.1|AYG84083.1|7015145_7015490_+|hypothetical-protein
MTAQPFDSVRPAGWLVDRVDLDGVGDKAAFMDRVATALRLPDWFGRNWDALADCLGDPDWGPARPGRLVVVTGWQEYAVERPEEWALALDVLGGAAGTGPHGTLAVHLALGGSH
>CP032698.1|AYG84082.1|7014726_7015149_+|Guanyl-specific-ribonuclease-St
MITRFARIALAAVLACLAVLLVGCGGKDSARTAGPSASASVSTPAWAKGMATVPADRLPPEARHTLTLIDKGGPFPYSKDGVVFGNVEKLLPRQKRGYYHEYTVDTPNSRDRGARRLITGQGGEFYYTDDHYKTFKAVLR
>CP032698.1|AYG84081.1|7013083_7014655_-|DNA-ligase-B
MLLADVATTSADIAATASRSEKSALLARLFSATEPDEAPLVVTYLAGRLPQRRTGLGWNTLKDLPPPADSPTLTVREVDERLEAISAVAGKGAQGERRRLVGELMAAATRGEQRFLVALITGEVRQGALDAAAVEGLAAAAGAPPAEVRRAVMLGGSLGTVARALLAEGPAALAAFRLEVGRPVLPMLAHSAKDVAEALDRLGPCVVEEKLDGIRAQVHKDGDAVRVFTRTLDEITERLPEVVDAARELAAERAVLDGEVIALGPDRRPRSFQDIAGRVGSRLDVAGAQERLPLSPVFFDLLSVDGRDLLDLSVRERHTELARIAPEPRRVRRYVVEDPADPEQRRGAEEFAAETLDLGHEGVVLKALDSTYAAGRRGASWLKVKPVHTLDLVVLAAEWGHGRRTGKLSNLHLGARREDGTFAMLGKTFKGLTDALLTWQTERLRELTVAEEPWGVRVRPELVVEVAYDGVQRSSRYPEGVTLRFARVVRYREDKRASEADTVASVTAPPGSRPGSNGEDGDA
>CP032698.1|AYG84080.1|7011711_7013061_-|Glutamine-synthetase
MEQGHSAGLREQAQRRAQEAGLAAARLTAEGVRAIALTWVDVAGLTRVKAVPTTRLAQVGAHGVGMSPVFDVYLVDDSVTTSPLIGGPDGDLRLIPDLDRLTVLAAQPGWAWAPAERFEQSGQPYDACQRQFARRMTRRAAERGIELRMGFETEWVVDPPLAGPAYGMARIVERSAYVGDVLAALEAQGVEVLQIHPEYTPGQFEVSVAPADPVGAADLAVLVRETIRAVSLQHGLTPWFGPVVDPEGVGNGGHLHLSLWQDGRNLCRGGEGPSGMSTTSESFLAGILDALPALLAIGAPTPASYLRLAPSRWAGAFQCWGPENREAALRFVPGPPGAEEAANAEVKSFDPAANPYLVTGAVIAAGLAGLDAGLRLPPPVAGDPVHSVGARRLPTSLPEALGRFTESAVLREALGDRLFEAIVAVRQAETKLFDGQTPGEIAAATRGRY
>CP032698.1|AYG84079.1|7010622_7011711_-|hypothetical-protein
MLPLVDHHCHGVLRSDPDDAAFEALLTESDAPAAPGTSFFDTQLGFAVRRWCPPLLGLEPHCPPERYLTRRRELGAEEANRLLLRATGIGTYLVDTGLPGDLTGPAELARLAGARAREIVRLEHLAERAAEGVRDPDKFLAVLADAIATAADTAAGFKSVVGYRHGLDFAPEPPGPAEVRAATADWLASGAGRITSPVLLRHLLWSAAGTGTALQLHTGFGDPDLTLHRCDPLLLTDFIRAIRPTGCRLVLLHGYPYHRGAGYLAHVYPHVYADVGLSLGHTGARAEAVLAEFLELAPFGKLLFSTDAYGLAELYVVGARLFQEGLDRLLNGWTASGAWSAADAERVAALVSAGNAERVYGR
>CP032698.1|AYG84078.1|7009558_7010584_+|Sorbitol-operon-regulator
MSAMSAGRSALRMGPAELVQAAAMARRFYLEGKSKIQIAEEFGVSRFKVARVLETALERDLVRIEIRVPAELDAERSDALRARYGLRHAVVVESPAEGEETSPDPENLGEVAADLLGELVSEGDVLGLAWGRSTIHMAAALDRLPPCTVVQLTGVYDAGTAERGSVEAVRRAAQVSGGEAHPIYAPMLLPDPATAAALRNQTGIARAFEYFDKVTVAAVSIGSWEPGISTVHDMLSDEERAHYASLGVAAEMSAHLFDAQGRRVGRDLGERCITVEADRLRRIPEVVAIAGGQRKAAAIDAVLRSGLVTSLVTDTAAADFLLGETGPKPRPALNRADPDGV
>CP032698.1|AYG84088.1|7021229_7022027_+|(R)-stereoselective-amidase
MPALRTALLQSSGSLSDVAANLKALDEAAGRAAATGAGLIVCPELFLTGYAIGDDVAKLAEAADGPSARAIAEIAVRHGLAVVYGYPERDGDAVYNAAQLIGPDGSRLANYRKTHLFGCFEQEAFTPGDQPVVQADLNGLRVGMMICYDVEFPENVRAHALAGTDLLLVPTAQMHPFQFVAESLVPVRAFENQLYVAYVNRTGPEGEFEFVGLSCLAGPDGAARARAGRGTELVVGDVDPEFLAASRANNPYLRDRRPGLYASLV
>CP032698.1|AYG84089.1|7022174_7023866_+|Tryptophan-2-monooxygenase
MTSTVPTAVQHIDEQPPVTMFGPDFPYAYDDFLAHPAGLGQIPATEHGAEVAVIGGGLSGVVAAYELMKMGLKPVVYEADQIGGRLRTVGFPGCDPELTAEMGAMRFPPCSTALQHYIDLVGLETKPFPNPLASDTPSTVVDLKGESHYATSVDELPAVYREVMDAWNACLEEGADFSDMNQAIRERDIPRIREIWAKLVEKFDNQTFYGFLCDSEAFKSFRHREIFGQVGFGTGGWDTDFPNSILEILRVVYTEADDLHRGIVGGSQQLPLRLWEREPEKLVHWAPGTSLSSLHDGAPRPAVTRLHRTAGNRITVTDADGDIRTFRAAIFTAQSWMLLSKIACDDSLFPIDHWTAIERTHYMESSKLFVPVDRPFWLDKDEETGRDVMSMTLTDRMTRGTYLLDNGPDKPAVICLSYTWCDDSLKWLPLSASERMEVMLKSLGEIYPKVDIRRHIIGNPVTVSWENEPYFMGAFKANLPGHYRYQRRLFTHFMQDSLPEDKRGIFLAGDDISWTAGWAEGAVQTALNAVWGVMHHFGGTTDASNPGPGDLYDEIAPVELPED
>CP032698.1|AYG84090.1|7023918_7024683_-|hypothetical-protein
MTQTAWSETGHLAHTHRFAAPLDPVVRRMRALRADLPPRDGIAVFNRVYLTVTEEISRLLAHGAFADPRAAATLDVLFAGRYLAAVEGTSFGRRPPDCWRPLFQYRRHPGVRPLQFALAGINAHIGHDLTLAVVDSCRALECEPAFLERDFDRVGDTLTLLEERIREELMPGPDLFQVADPMTHLLASWSLERARDASWSAAKVLWQLRELPSLAREFTERLDAGVGLVTRCLLTPLAASAHASARPAWEDDHW
>CP032698.1|AYG84091.1|7024880_7026260_-|Putative-pyrimidine-permease-RutG
MRLGVRWTLHGDGRTPAPGAVVRPDERLSWPRTIGLGAQHVVAMFGASFVAPVLMGLDPNLAIMMSGIATVIFLLATKGRVPSYLGCSLSFVGVAAAIRATGGTSATVTGAVFVVGVVLFFAGLAVQRFGARIIHAAMPPIVTGAVVMLIGFNLAPVTAATYWPQDQWTALMVMLFTGLAVVCLRGFWSRVAIFLGLIFGYGVSWLLDRVFGKIHSVHGGTEAVDHWRLDLSGFAKADWIGLPSFHAPSFEWSAILVALPVVIALIAENAGHVKAVGEMTGADLDDKLGTAIAADGAASMLSTAVGGPPNTTYSENIGVMAATRVYSTAAYWAAAGFALLFGVCPKFGAVVAAIPGGVLGGITVILYGMIGLLGAQIWINAKVDLRNPLNLVPAAAGIIIGIGNVTLKFSENFQLSGIALGTIVVITGYHVLRAFAPAHLKEQEPLLDSGTSSYEKDQA
>CP032698.1|AYG84092.1|7026537_7027815_+|hypothetical-protein
MSGRPRRGLVAVLSLAVAIASALVPATSYAAPATAKAPRTVVLDGRRLQDTKRRLDHGDPQLRAALSQLTATADGWLGQGPWTVVDKPKPAPGGDVHDYLSQAPYWWPSQPKTAANPWGCPYVQKDGQRNPEVDTGTDRPDLGKVFNSVTSLSLAWYYTGRRQYAEHASAILRTWFLDPATRMNPNLDHGQFIPCTYDGRAIGIIDFSQQYSSVLDAIAVLDTGAPGWSAGDSSAMLAWNKAFLDWEVNSAFGKEESAAANNHGTFQDLQIAALALATGDRGLARRTVLGAEKLRIDPQIAADGSQPQELSRTRSWHYSTFDLVAYTRLAAIGNQVGVHLWTYRGPQGQSLFEAVRYVLPAATAAAAWTHPELEFHRYAASDVVHAAADAGDRAAKAAVPRLQAPPGGDLWALRPAAEQLDSIAG
>CP032698.1|AYG84093.1|7027861_7029064_-|Inner-membrane-protein-YbjJ
MAAELALEQRQLRRARIAVAAVFCVHGAVTGNFATRVPWIQEHAGVSAGQLGLALAFPAIGSSLLMPLTGAISHRFGARGALRVLLALWTLALALPALAPNVYTLCAVLFAYGASAGMADVAMNALGVETENRLGRSIMSSLHGMWSVGALIGSAAGTLAAHLGADARLHHAIAAGVLTLLGLVACQGVLDLRSAPGEAPPPRFALPPRSALLIGLVGFCAVFAEGASLDWSAVYLRDVLDTSAGTAAACTTAFTLTMAVARLAGDKGVDRFGAVRTVRAGGVLATLGGVLVVIAPGAAVAMAGFALLGLGVAVVVPLAFAAAGRSGPNPSQAIAGVATITYTSGLVAPSAIGTIADLTSLVVSFGLVTVLALGLVVGARVLRTGPGPQEKAAPAPARQT
>CP032698.1|AYG84094.1|7029135_7030326_+|N-acetylglucosamine-repressor
MNGRDRNPSSVIWKDPRMPASPSTARAINDRLALRLLQDEGPLTAGQLKTLTGLSRPTVADLVERLQGSGLVHVVGESGAERRGPNARLYALVADRAHLAALDVRTHGVCLVVADLLGQTLAEATLPVEPDAGTGPAVEQVVALLERTAKEAGAERLHSVAVGAPGLIDPASGELRDTSGLPAWHRELVRVLAQRLPAAVLVENETNLAAVAEQRLGAARGQDTFVLMWLGQGIGAAVVLDGEVRRGASGGAGEIGFMPVPGTSGLPSATGCDGGFHELAHAGAVARLAAEYGRPGGAEEAVRDADGPFLDALAERLAIGAASVVAVLDPGLIVLGGELGHAGGQLLASRVRRALSALTPLATEVRPSALGDGAVLSGALLTARDAAQDELFGPKA
>CP032698.1|AYG84095.1|7030441_7032805_-|Chitodextrinase
MFSPTRRRTVLLTTATAVAGLLFGALSTGVSQAAVDNEACRPDGLYKTPGVDVPYCSVYDTEGREKMGADHQRRVIGYFTGWRTGQDGTPAYLASDIPWDKVTHVNYAFAHAGSDNKVSVGSDSEKNAATGMTWPGVAGAEMDPALPYKGHFNLLNKFKKQHPNVKTLISVGGWAETGGYFGDDGKRVGSGGFYSMATNADGSVNQAGIDTFADSAVAFIKKYGFNGVDIDYEYPTTMKDAGNPLDLTLSNARRAGLVKGYAALMKSLREKLDRAGAADAKHYLLSVAAPSSGYLLRGMETFQVQQYLDYVNIMSYDLHGAWNQYVGPNASLFDDGKDPELASAGVYSTSQYGGIGYLNADWAYHYFRGSMPAGRINMGLPYYTRGFQNVQGGTNGLWGKAPSTTCPAGAGLTTCGDGAVGVDNLWHDLDTNGKEAPAGSNPMWHAKNLEKGIVGDYVTKYGLPADTKLTGSYVRNYDATLVAPWLWNDRKKVFLSTEDEQSVNAKADYVVDKGIGGTMVWELAGDYQWNAAKGQYQQGSTLTSAMYDKFKSATPYGNRRSTIALPGQALNIGVDFGQFPLGDSNYPISPKVTLTNNTTATLPGGTEFQFDYGTSAPANAKDQSGFGTTIVRSDHTAANNIGGLKGDYNRVSLKLPSWQSLAPGASVTLDFVYYLPVSTPSNWTVTFGGKTYALAGDHTRGAVVSDPGTSSPTPTPTPTPSGATGPSPSPTPSGGTCSAPLWSAGSAYGGGTSVSYKSHTWKSKWWTKGEEPGTTGDWGVWQDLGPC
>CP032698.1|AYG84096.1|7033400_7034489_+|Riboflavin-biosynthesis-protein-RibD
MAPTADADAMRRAIELAARGLGSTSPNPVVGCVITDASGTVVGEGFHQRAGGPHAEVHALADAGERARGGTAYVTLEPCNHTGRTGPCAQALIEAGITRVHYAVGDPNPQATGGADTLRAAGIHVEQGLLGAEAEAGNAAWLTSVRLGRPHVTWKYAATLDGRTAAEDGTSRWITSADSRADVHRLRAECDAVVVGSGTVRTDDPHLAVRGVEGATQPLRLAVDTNATAVKPGARILDDAAPTLIAVAEDADAGHLPEAAVLRVPRAATGLDIPALLAALHTRGVRSVLLEGGPTLAGAFVAAGAVDRVVGYLAPALLGAGPAALAGAGIPTIADALRLDLTEAVRIGPDLRITATPLAKES
>CP032698.1|AYG84097.1|7034491_7035100_+|Riboflavin-synthase
MFTGIVEELGEVTAIETLGDASRFRLRGPLVTEGAGHGDSIAVNGVCLTVVEFGDGEFTADVMDETLKRSSLGALEVGSRVNLERPMAVGGRLGGHIVQGHVDGTGTVLARTPSENWEIVKIALPGELSKYVVEKGSITVDGVSLTVVEAAADYFTISLIPTTLALTTLGIKQPGDPVNLEVDVIAKYVERLLGASHGGNDK

Crispr_ID: CP032698_93

• CRISPR_ID: CP032698_93
• CRISPR_location: 7161503-7161603
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_93

Consensus_repeat	Method
CCCCTGGGGCTCCGCCCCAGACCCC	CRISPRCasFinder

spacers of CP032698_93

>93.1|7161528|51|CP032698|CRISPRCasFinder
AGGCGCGCTTGCCCACCCACCCGCCCGTGACGGGGGTTGGACAGCCCCGGG

CRISPR arrays and Neighbor proteins around CP032698_93

CRISPR arrays

The CRISPR arrays of CP032698_93

>merge|CP032698|93|7161503-7161603|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCCAGGCGCGCTTGCCCACCCACCCGCCCGTGACGGGGGTTGGACAGCCCCGGGCCCCTGGGGCTCCGCCCCAGACCCC

>CP032698|93|68|7161503-7161603|CRISPRCasFinder
CCCCTGGGGCTCCGCCCCAGACCCC	AGGCGCGCTTGCCCACCCACCCGCCCGTGACGGGGGTTGGACAGCCCCGGG
CCCCTGGGGCTCCGCCCCAGACCCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG84210.1|7159315_7160014_+|hypothetical-protein	unknown	unknown	gnl|CDD|132881
CP032698.1|AYG84203.1|7154400_7155222_+|Short-chain-enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|236205
CP032698.1|AYG84220.1|7170340_7171084_+|Putative-acetyltransferase	unknown	unknown	gnl|CDD|100053
CP032698.1|AYG84202.1|7153874_7154354_-|hypothetical-protein	unknown	unknown	gnl|CDD|379275
CP032698.1|AYG84211.1|7160307_7161498_+|Elongation-factor-Tu	unknown	unknown	gnl|CDD|237184
CP032698.1|AYG84218.1|7169199_7169643_-|hypothetical-protein	unknown	unknown	gnl|CDD|225961
CP032698.1|AYG84216.1|7165942_7168420_+|Thermostable-beta-glucosidase-B	unknown	unknown	gnl|CDD|224389
CP032698.1|AYG84221.1|7171164_7172031_-|hypothetical-protein	unknown	unknown	gnl|CDD|225308
CP032698.1|AYG84205.1|7156211_7156409_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84213.1|7162737_7164054_-|hypothetical-protein	unknown	unknown	gnl|CDD|340863
CP032698.1|AYG84204.1|7155246_7156047_-|hypothetical-protein	unknown	unknown	gnl|CDD|173926
CP032698.1|AYG84209.1|7158444_7159149_-|TVP38/TMEM64-family-inner-membrane-protein-YdjZ	unknown	unknown	gnl|CDD|223475
CP032698.1|AYG84215.1|7165252_7165690_+|hypothetical-protein	unknown	unknown	gnl|CDD|373120
CP032698.1|AYG84207.1|7156922_7157300_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84206.1|7156525_7156702_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84208.1|7157330_7158320_-|Undecaprenyl-diphosphatase	unknown	unknown	gnl|CDD|237134
CP032698.1|AYG84219.1|7169738_7170269_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	unknown	unknown	gnl|CDD|100051
CP032698.1|AYG84217.1|7168495_7169152_+|putative-membrane-protein	unknown	unknown	gnl|CDD|223659
CP032698.1|AYG84212.1|7161915_7162776_+|Polyamine-aminopropyltransferase	unknown	unknown	gnl|CDD|223498
CP032698.1|AYG84214.1|7164111_7165143_-|hypothetical-protein	unknown	unknown	gnl|CDD|370676

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG84210.1|7159315_7160014_+|hypothetical-protein	gnl|CDD|132881	cd07064, AlkD_like_1, A new structural DNA glycosylase containing HEAT-like repeats. This domain represents a new and uncharacterized structural superfamily of DNA glycosylases that form an alpha-alpha superhelix fold that are not belong to the identified five structural DNA glycosylase superfamilies (UDG, AAG/MNPG, MutM/Fpg and helix-hairpin-helix). DNA glycosylases removing alkylated base residues have been identified in all organisms investigated and may be universally present in nature. DNA glycosylases catalyze the first step in Base Excision Repair (BER) pathway by cleaving damaged DNA bases within double strand DNA to produce an abasic site. The resulting abasic site is further processed by AP endonuclease, phosphodiesterase, DNA polymerases, and DNA ligase functions to restore the DNA to an undamaged state. All glycosylase examined to date utilize a similar strategy for binding DNA and base flipping despite their structural diversity. The known structures for members of this family, AlkC and AlkD from Bacillus cereus, are distant homologues and are composed of six variant HEAT (Huntington/Elongation/ A subunit/Target of rapamycin) repeats. HEAT motifs are ~45-amino acid sequences that form antiparallel alpha-helices, which are packed by a conserved hyrophobic interface and are tandemly repeated to form superhelical alpha-structures. AlkD and AlkC are specific for removal of 3-methyladenine (3mA) and 7-methylguanine (7mG) from the DNA by base excision repair. Homologues of AlkC and AlkD were also identified in other organisms.	1.80607e-98
CP032698.1|AYG84203.1|7154400_7155222_+|Short-chain-enoyl-CoA-hydratase	gnl|CDD|236205	PRK08259, PRK08259, crotonase/enoyl-CoA hydratase family protein.	3.29117e-156
CP032698.1|AYG84220.1|7170340_7171084_+|Putative-acetyltransferase	gnl|CDD|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	1.70826e-40
CP032698.1|AYG84202.1|7153874_7154354_-|hypothetical-protein	gnl|CDD|379275	pfam13577, SnoaL_4, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.4831e-23
CP032698.1|AYG84211.1|7160307_7161498_+|Elongation-factor-Tu	gnl|CDD|237184	PRK12736, PRK12736, elongation factor Tu; Reviewed.	0
CP032698.1|AYG84218.1|7169199_7169643_-|hypothetical-protein	gnl|CDD|225961	COG3427, COG3427, Carbon monoxide dehydrogenase subunit G, CoxG [Energy production and conversion].	0.00147325
CP032698.1|AYG84216.1|7165942_7168420_+|Thermostable-beta-glucosidase-B	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	3.86693e-73
CP032698.1|AYG84221.1|7171164_7172031_-|hypothetical-protein	gnl|CDD|225308	COG2510, COG2510, Predicted membrane protein [Function unknown].	8.29487e-05
CP032698.1|AYG84213.1|7162737_7164054_-|hypothetical-protein	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.72797e-48
CP032698.1|AYG84204.1|7155246_7156047_-|hypothetical-protein	gnl|CDD|173926	cd04301, NAT_SF, N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate. NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.	0.000120239
CP032698.1|AYG84209.1|7158444_7159149_-|TVP38/TMEM64-family-inner-membrane-protein-YdjZ	gnl|CDD|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	2.06329e-25
CP032698.1|AYG84215.1|7165252_7165690_+|hypothetical-protein	gnl|CDD|373120	pfam14539, DUF4442, Domain of unknown function (DUF4442). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 139 and 165 amino acids in length. There is a conserved PYF sequence motif. There is a single completely conserved residue N that may be functionally important.	4.70551e-22
CP032698.1|AYG84208.1|7157330_7158320_-|Undecaprenyl-diphosphatase	gnl|CDD|237134	PRK12554, PRK12554, undecaprenyl pyrophosphate phosphatase; Reviewed.	5.34543e-137
CP032698.1|AYG84212.1|7161915_7162776_+|Polyamine-aminopropyltransferase	gnl|CDD|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	6.26305e-14
CP032698.1|AYG84219.1|7169738_7170269_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	gnl|CDD|100051	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed by the regeneration of the active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. They are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionary distinct groups - alpha, beta and gamma carbonic anhydrases - which show no significant sequence identity or structural similarity. Gamma CAs are trimeric enzymes with left-handed parallel beta helix (LbH) structural domain.	4.35396e-83
CP032698.1|AYG84217.1|7168495_7169152_+|putative-membrane-protein	gnl|CDD|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	4.51393e-41
CP032698.1|AYG84214.1|7164111_7165143_-|hypothetical-protein	gnl|CDD|370676	pfam09770, PAT1, Topoisomerase II-associated protein PAT1. Members of this family are necessary for accurate chromosome transmission during cell division.	2.24816e-06

Protein sequences

>CP032698.1|AYG84211.1|7160307_7161498_+|Elongation-factor-Tu
MPKTAYVRTKPHLNIGTMGHVDHGKTTLTAAITKVLAEREGGTTTRYVSFDRIDRAPEEAARGITINIAHVEYETDTRHYAHVDMPGHADYVKNMVTGAAQLDGAILVVSALDGIMPQTAEHVLLARQVGVDHIVVALNKADAVDDGEDAVLTDLVELEVRELLSAHGYGGDGVPVVRVSGLKALEGEPRWTEAIGALLDAVDTYVPLPERYVDAPFLLPVENVLTITGRGTVVTGAVERGTVRVGDRVRVLGAEVESVVIGLETFGKPMDSAQAGDNVALLLRGVARDAVRRGHVVAEPGSVTPSRRFTAQVYVLSTREGGRATPIATGYRPQFYIRTADVVGDVDLGELAVARPGDTVTMTVELGRDMALEPGLGFAIREGGRTVGAGTIATLL
>CP032698.1|AYG84210.1|7159315_7160014_+|hypothetical-protein
MTPRAPHSPLADDVLARLVRVYPEGGDPHRAGEMVAYMKGVAPFLGIRSPERRALSRTVLDGLAKPAEADCAAVALRCWALEEREYHYFAVDYLRRYVRVCSSAFLPVARHLVVTTSWWDTVDHLAAHVVGPLVAADAELAGVMDRWIDDDDLWLARTALLHQLTYKERTDANRLFDYCLRRAAHPDFFIRKAIGWSLREYAKSDPGAVRAFVAAEGERLSPLSVREALKNL
>CP032698.1|AYG84209.1|7158444_7159149_-|TVP38/TMEM64-family-inner-membrane-protein-YdjZ
MFQPAARSTSGLAARCGRALLSPWSRLTLLVVVLAAAGSAVLVLQPQRLLADGWPPQLGGAGAVALFALAYGLCAAAFVPRPILNLAAGALFATSAGFVSSLVGTVLGAGIAFGLGRVLGQDALRPLVRGRWLKAADGQLSRHGFRSMMAIRLFPGVPFAAANYCAAVSRMGWAPFLLATGLGSVPNTLAYVVAGGSASSPTSPAFLIAMGFIVLSGAAAATVAWRKRQALRKR
>CP032698.1|AYG84208.1|7157330_7158320_-|Undecaprenyl-diphosphatase
MPLDPREITGGPTAAPGFRRVLGVPNGRDPDPPWMAQHPMSWFESFILGLVQGLTEFLPISSSAHLRLTAAFAGWQDPGPAFTAITQIGTETAVLIYFRSDIARIVSAWFRSLTDRSLRADPDARMGWLVIVGSIPIGVLGIVLKHQIDTSFRDLRVIATTLVAMGVVLGIADRLAARDESGGRHRAARERKSLRELGTRDGLIYGICQAMALIPGVSRSGATISGGLLMGYTCEAAARYSFLLAVPAVLASGVFELKDAGGPGQAPLLPTLVAAVIAFAVGYAVIAWFMTFISTKSFMPFVVYRIVLGIALFVLIAVGTLAPDAGGGL
>CP032698.1|AYG84207.1|7156922_7157300_+|hypothetical-protein
MEQSEVLKRVIGILTEAGDYRRRIEQDEERGSRNTEIGIVTALLNETMPHIEIPADATPQEMATLVAREVGGAIQQLVAAFSLAFVALAQVHDSGEQDVSSADVLQDLALRAEEAKGDGPQTSRE
>CP032698.1|AYG84206.1|7156525_7156702_-|hypothetical-protein
MPPTYDCRSLRPADVVNAEIRSLWEQSDGRLSPDEEERYHGLLVEWAAAVRDNTAQAA
>CP032698.1|AYG84205.1|7156211_7156409_-|hypothetical-protein
MSSSSERPGPTPSDADAANDAIRALVDGADGQWPAEEYERLLADWAAAVGETTPLAAGAVSKPRT
>CP032698.1|AYG84204.1|7155246_7156047_-|hypothetical-protein
MHTDAPAGAPDDELLAVFDRQMRQHALPDGPGATVERSGDVLRQVGPAPVWNGILWSDLTASSADAEIAAQVRHFAALGNEFEWKLYAHDRPSDLGLRLAAAGFEAEPEETVMVARVADLPLDVEPPAGITLRPVVDEAGVALMTRVHDGAFGPGSARVGERLLAQFIQAPETVTAVVAMAGEVPVSAARMEVHPGTEFASLWGGGTLPEWRGRGIYRALIAYRTRVAAERGCRYLQVDASDRSRPILRRLGFVPLTLTTPYIRRA
>CP032698.1|AYG84203.1|7154400_7155222_+|Short-chain-enoyl-CoA-hydratase
MWLVDASCYRWRMTDETTPAVRSERNGPVTTVILSRPRARNAVDGPTARALAEAFRAFEADERAAVAVLWGEGGTFCAGADLKAIGTERGNTVTEDSDGPMGPTRLRLSKPVIAAVAGHAVAGGLELALWCDLRVMEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGAGRAMDLVLTGRPVDAAEAHAIGLADRVVPPTTARARAERLAAEIAAFPQTCLRHDRMSLLEQEGLGETEALLGEVRHGVHALAEAAEGAARFAAGAGRHGTFDNTA
>CP032698.1|AYG84202.1|7153874_7154354_-|hypothetical-protein
MTQRVDLGTLLDRLAIDELITGYAAAVDDGDWAAYRALFAPDGRADYGAAGGIAGSVEEVARWLAETLRLFPVRQHLITNRLLTLQDLGGYPGDRAELRADYLNPMCFGGDGDGAPSAPDFESGGRYAFSLLRTEAGWRLSSVTVHEKWRRMSGALAGG
>CP032698.1|AYG84212.1|7161915_7162776_+|Polyamine-aminopropyltransferase
MNDDHRSAPIPVTRDVDQGTAKLLPDIDRERAWLLTVNGAPQSYVDLDDPTYIEFEYVRRLAHVVDCAAEEGAPLDVLHLGGGALTLPRYVAATRPGSRQDVVEADRALLQLVREKLPLAPGIGVTPHAADARAWAQAAPAASVDLLIADVFGGSRVPAHLTSVEYARVAERVLKPEGIYAANLADGAPFTFLRSQLATFQAVFAEVALIAEPSVLRGRRFGNAVLLASRHPLDVAALARRTAGDAFPARVEHGDALRRFIAQAPMVDDTAARPSPEPPEGAFGIG
>CP032698.1|AYG84213.1|7162737_7164054_-|hypothetical-protein
MTSAAIPPPARTSPPARRPSWAGRNYTLLTAAAIVTNLGSQGALIAAAFAVLSSGGDAGDVGLVAAARTVPLVLFLLVGGALADRLPRHRVMVAANTLNFLSQGAFALLVLTGDPRLWQMMVLTALGGVGQAFFGPASEGMLMSSVSGVEAGRAFAFYRMAMHGAGIGGAALGGALIAAFGPGWVLAIDAAAFAVAGALRAFLDVSHIPARSAGGGMVSDLREGWREFVTRPWLWAIVVQFAVVNAVVAAAEAVYGPLVARDELGGPGPWGLALAAFGAGTVAGAFLMMRWKPRRLLLAGSLCVFPLALPSAALAVPLPVAGLAAVMLLTGVSIEVFGVSWMTALNQEIPEEKLSRVSAYDWLGSIAMVPVATALAGPAQNAVGRTSALWGCSALIVLLTAAVLCVPDVRRLTRRGEPVALAGPAASADAEGALGRLG
>CP032698.1|AYG84214.1|7164111_7165143_-|hypothetical-protein
MWPGQQPPGGEQNPQDPNQNPYQQPGYQQPNPYQQPGQQPPGYPPQGYQTPNPYQQPTVPQYPVAGPPGPPQPPQNNDKKKTTIIAIVAATAVVVAAAVTGVVVLKDDDKGTPQADGKNTKSPSAPASDSAAPSSPAPNPRGAGAAVQPVIAGWKVVVNPAKGDAFDVPPDWEVDSPTMSTGWSDDADPNGFGGMTMSAPAYYKSKWCTTKSSSGRDVSTRLVTVGTKGANGAKDTGEAAEQADDWLYFAYTQPDKDHITGEKPVPYTTKSGLQGSVARAKTTGVKKTDKCSTEGQSVLFGFKTAKGDLAAWSLIANTGVPDAVSEDTIQKILSTIRLVPATS
>CP032698.1|AYG84215.1|7165252_7165690_+|hypothetical-protein
MSVGEMLTATVPMARTLELEFLETTPERAVVRLPDRAEYHNHLGGPHAGAMFTLAESASGAIVIAAFGDQMHRAVPLAVKAEIGYKKLAKGVVTATATLGRPIADVVADLDAGQRPEFPVVIEIQRADGAVTGEMTVVWTLRPNS
>CP032698.1|AYG84216.1|7165942_7168420_+|Thermostable-beta-glucosidase-B
MSDTVSRRAALRLLAGAATVAAAATGDFTASARPRTDAPGSRRTEALLGRLTLDEKIGLLHGSEDPHGLGQAGYLPGVPRLRIPPLRLADGPAGVRVTAHATALPAPVMLAATFDPALAREYGEVIGREGRALGQDVLLSPMVNLIRTPYAGRNFETFSEDPLLSADLVAEEIHGIQSQGLIATVKHFALNNQEKDRLTLDARIAEQPLRELELRGFEAAVAAGVGAVMGAYNKVNGAFACENKPILTDVLRTDWGFEGWVMTDWFATHGLAALAAGLDMEMPAGVHFADTLKAAVLDGSVPEALVDRAVRRVLSVMERFGLLDGSAPARPARDARRGARTALTVARAGATLLHNRHATLPLAGAAARHIAVIGPTAVIPFVSGGGSAHVVPDHARRPLDALRDRAGDGARVCHTLGEDLYGKPLPGTSPGADFEGQHVDPGATWTYDGTLTVTEDDEWTFCIHYSGDRPKVVLDGTELFPPAPGLGELFGGGLVGTAPDGLAVRRATLTLAAGAHRLVITAKGREAGQLFRLRRVTGATRAADVAAAVRAARAASSVVLFAYEDATEGADRTHLALPGHQNELIEAVAAVNSRTTVVLNTSSCTTMPWLGRVGAVLQMYYPGQEGADATAAVLFGECDPGGRLTQTFPVSEDRHPMAGDPRRYPGVDGTEEYSEGLRPGYRWYDAEGVSPLFPFGHGLSYTTFAYTDLSVRPDGDGLAVAFTVRNTGHRTGVTVAQVYLGPSPDLGLDQVRRALAGYRRLELEPGHDRRVTVRVGARSLSSWDPERHAWVLGTGRREVSVGVSAGETLLVGHGSVAARPPAGRP
>CP032698.1|AYG84217.1|7168495_7169152_+|putative-membrane-protein
MHIQEWLEHIPAVSVYLLVALVIGVESLGIPLPGEIVLVSSALLASQQGHINPVVLGACATAGAVIGDSIGYAIGRKGGRPLLAWLGRKFPKHFSEGHVAMAERSFQKWGMWAVFFGRFIALLRIFAGPLAGVLHMPYWKFLIANVLGGICWAGGTTAVIYYLGIVAESWLKNFSYLGLVAALLIGVASMLVVKNRAKKSMAEAEAAQSTPENVPAGD
>CP032698.1|AYG84218.1|7169199_7169643_-|hypothetical-protein
MALFRIDRRTELTPAEAWHRLTDWERHGEGVPFTRITVRTPPPTGPGTVFVARTGLGRLAFADPMEITRWRPPSEGRPGVCRLEKRGRVITGWAEIEVAASGAGALVVWREELRVRGLPRALDPLTAAAGRLVFGRALTVLLRDRTP
>CP032698.1|AYG84219.1|7169738_7170269_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase
MAEQALVVAVGGKAPEIAPTAFTAPTSVVLGEVTLGAGASVWYHAVLRADCGPIVIGAESNIQDNCTVHVDPGFPVILGERVTVGHNAVLHGCTVEDDVLVGMGATILNGARIGAGSLIAAHALVPQGMVVPPGSLVAGVPAKVRRELSEEEREGIKVNALMYLGLAEDHRAAHAG
>CP032698.1|AYG84220.1|7170340_7171084_+|Putative-acetyltransferase
MPKNRNTFSSLTAWRREIASRAVHGGWDWIKRTGAVTAEHPGRLRFRRIGAGTRLAFPQGTVFGEPWIELGDHCIIGEQVTLTAGMMPGLDLGTEPILTLGNGVVLGRGSHVIADTTITIGSDTYCGPNVYITSTNHSYDDPRQPVGKQWPRMEPVEIGPGCWLGTGAVVLPGARLGRNVVVAAGAVVRGEVPDHAVVAGAPAKIVRTWDERDGWQPPLRTPAPVPIPDGVTPEQLLAIAELSPEEA
>CP032698.1|AYG84221.1|7171164_7172031_-|hypothetical-protein
MTALFALATSLLWGLADFGGGLLTRRMPALTVVVASQTVAVVVLGSVVLATGGLREAAPQLWFAVAAGAVGPVAMLSFYKALALGPMGVVSPLGSLGVAVPVGVGLALGERPGLLQFAGIAVAVAGVLLAGGPEFRGAAVQRQAVLLTLLAAFGFGAVMALISEASTTVTGLFLALFVQRVTNVAVGGTALLVSVRRGGAALPADGGSRAVWLALPALAFVGLADVAANGTYAIAAQRGPVTVAAVLASLYPVVTALAARGVLKERLRTVQAAGAGLALVGTVLLATG

Crispr_ID: CP032698_94

• CRISPR_ID: CP032698_94
• CRISPR_location: 7161676-7161828
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_94

Consensus_repeat	Method
CAGGGGCGCGGGGAACTGCGCGAGAAGCGA-GCACGACCC	PILER-CR

spacers of CP032698_94

>94.1|7161715|37|CP032698|PILER-CR
CCCAGCCCCGCACGGCCCGCAGCCAAAAACGGGTTTC
>94.2|7161791|17|CP032698|PILER-CR
GCACGGTGGAGGGGGTG

CRISPR arrays and Neighbor proteins around CP032698_94

CRISPR arrays

The CRISPR arrays of CP032698_94

>merge|CP032698|94|7161676-7161828|PILER-CR
AGGGGCGCGGGGAACTGCGCGCCCAGCCCCGCACGGCCCGCAGCCAAAAACGGGTTTCCAGGGGCGCGAGGAACTGCGCGAGAAGCGAGCACGGCCCGCACGGTGGAGGGGGTGCAGGGGCGCGGGAAACTGCGCGAGAAGCGAGCACGACCC

>CP032698|94|24|7161676-7161828|PILER-CR
AGGGGCGCGGGGAACTGCGCGCCCAGCCCCGCACGGCCC	GCAGCCAAAAACGGGTTTCCAGGGGCGCGAGGAACTG
CGCGAGAAGCGAGCACGGCCCGCACGGTGGAGGGGGTGC	AGGGGCGCGGGAAACTG
CGCGAGAAGCGAGCACGACCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG84210.1|7159315_7160014_+|hypothetical-protein	unknown	unknown	gnl|CDD|132881
CP032698.1|AYG84203.1|7154400_7155222_+|Short-chain-enoyl-CoA-hydratase	unknown	unknown	gnl|CDD|236205
CP032698.1|AYG84220.1|7170340_7171084_+|Putative-acetyltransferase	unknown	unknown	gnl|CDD|100053
CP032698.1|AYG84202.1|7153874_7154354_-|hypothetical-protein	unknown	unknown	gnl|CDD|379275
CP032698.1|AYG84211.1|7160307_7161498_+|Elongation-factor-Tu	unknown	unknown	gnl|CDD|237184
CP032698.1|AYG84218.1|7169199_7169643_-|hypothetical-protein	unknown	unknown	gnl|CDD|225961
CP032698.1|AYG84216.1|7165942_7168420_+|Thermostable-beta-glucosidase-B	unknown	unknown	gnl|CDD|224389
CP032698.1|AYG84221.1|7171164_7172031_-|hypothetical-protein	unknown	unknown	gnl|CDD|225308
CP032698.1|AYG84205.1|7156211_7156409_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84213.1|7162737_7164054_-|hypothetical-protein	unknown	unknown	gnl|CDD|340863
CP032698.1|AYG84204.1|7155246_7156047_-|hypothetical-protein	unknown	unknown	gnl|CDD|173926
CP032698.1|AYG84209.1|7158444_7159149_-|TVP38/TMEM64-family-inner-membrane-protein-YdjZ	unknown	unknown	gnl|CDD|223475
CP032698.1|AYG84215.1|7165252_7165690_+|hypothetical-protein	unknown	unknown	gnl|CDD|373120
CP032698.1|AYG84207.1|7156922_7157300_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84206.1|7156525_7156702_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84208.1|7157330_7158320_-|Undecaprenyl-diphosphatase	unknown	unknown	gnl|CDD|237134
CP032698.1|AYG84219.1|7169738_7170269_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	unknown	unknown	gnl|CDD|100051
CP032698.1|AYG84217.1|7168495_7169152_+|putative-membrane-protein	unknown	unknown	gnl|CDD|223659
CP032698.1|AYG84212.1|7161915_7162776_+|Polyamine-aminopropyltransferase	unknown	unknown	gnl|CDD|223498
CP032698.1|AYG84214.1|7164111_7165143_-|hypothetical-protein	unknown	unknown	gnl|CDD|370676

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG84210.1|7159315_7160014_+|hypothetical-protein	gnl|CDD|132881	cd07064, AlkD_like_1, A new structural DNA glycosylase containing HEAT-like repeats. This domain represents a new and uncharacterized structural superfamily of DNA glycosylases that form an alpha-alpha superhelix fold that are not belong to the identified five structural DNA glycosylase superfamilies (UDG, AAG/MNPG, MutM/Fpg and helix-hairpin-helix). DNA glycosylases removing alkylated base residues have been identified in all organisms investigated and may be universally present in nature. DNA glycosylases catalyze the first step in Base Excision Repair (BER) pathway by cleaving damaged DNA bases within double strand DNA to produce an abasic site. The resulting abasic site is further processed by AP endonuclease, phosphodiesterase, DNA polymerases, and DNA ligase functions to restore the DNA to an undamaged state. All glycosylase examined to date utilize a similar strategy for binding DNA and base flipping despite their structural diversity. The known structures for members of this family, AlkC and AlkD from Bacillus cereus, are distant homologues and are composed of six variant HEAT (Huntington/Elongation/ A subunit/Target of rapamycin) repeats. HEAT motifs are ~45-amino acid sequences that form antiparallel alpha-helices, which are packed by a conserved hyrophobic interface and are tandemly repeated to form superhelical alpha-structures. AlkD and AlkC are specific for removal of 3-methyladenine (3mA) and 7-methylguanine (7mG) from the DNA by base excision repair. Homologues of AlkC and AlkD were also identified in other organisms.	1.80607e-98
CP032698.1|AYG84203.1|7154400_7155222_+|Short-chain-enoyl-CoA-hydratase	gnl|CDD|236205	PRK08259, PRK08259, crotonase/enoyl-CoA hydratase family protein.	3.29117e-156
CP032698.1|AYG84220.1|7170340_7171084_+|Putative-acetyltransferase	gnl|CDD|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	1.70826e-40
CP032698.1|AYG84202.1|7153874_7154354_-|hypothetical-protein	gnl|CDD|379275	pfam13577, SnoaL_4, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	2.4831e-23
CP032698.1|AYG84211.1|7160307_7161498_+|Elongation-factor-Tu	gnl|CDD|237184	PRK12736, PRK12736, elongation factor Tu; Reviewed.	0
CP032698.1|AYG84218.1|7169199_7169643_-|hypothetical-protein	gnl|CDD|225961	COG3427, COG3427, Carbon monoxide dehydrogenase subunit G, CoxG [Energy production and conversion].	0.00147325
CP032698.1|AYG84216.1|7165942_7168420_+|Thermostable-beta-glucosidase-B	gnl|CDD|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	3.86693e-73
CP032698.1|AYG84221.1|7171164_7172031_-|hypothetical-protein	gnl|CDD|225308	COG2510, COG2510, Predicted membrane protein [Function unknown].	8.29487e-05
CP032698.1|AYG84213.1|7162737_7164054_-|hypothetical-protein	gnl|CDD|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.72797e-48
CP032698.1|AYG84204.1|7155246_7156047_-|hypothetical-protein	gnl|CDD|173926	cd04301, NAT_SF, N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate. NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.	0.000120239
CP032698.1|AYG84209.1|7158444_7159149_-|TVP38/TMEM64-family-inner-membrane-protein-YdjZ	gnl|CDD|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	2.06329e-25
CP032698.1|AYG84215.1|7165252_7165690_+|hypothetical-protein	gnl|CDD|373120	pfam14539, DUF4442, Domain of unknown function (DUF4442). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 139 and 165 amino acids in length. There is a conserved PYF sequence motif. There is a single completely conserved residue N that may be functionally important.	4.70551e-22
CP032698.1|AYG84208.1|7157330_7158320_-|Undecaprenyl-diphosphatase	gnl|CDD|237134	PRK12554, PRK12554, undecaprenyl pyrophosphate phosphatase; Reviewed.	5.34543e-137
CP032698.1|AYG84212.1|7161915_7162776_+|Polyamine-aminopropyltransferase	gnl|CDD|223498	COG0421, SpeE, Spermidine synthase [Amino acid transport and metabolism].	6.26305e-14
CP032698.1|AYG84219.1|7169738_7170269_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase	gnl|CDD|100051	cd04645, LbH_gamma_CA_like, Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism, involving the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide, followed by the regeneration of the active site by ionization of the zinc-bound water molecule and removal of a proton from the active site. They are ubiquitous enzymes involved in fundamental processes like photosynthesis, respiration, pH homeostasis and ion transport. There are three evolutionary distinct groups - alpha, beta and gamma carbonic anhydrases - which show no significant sequence identity or structural similarity. Gamma CAs are trimeric enzymes with left-handed parallel beta helix (LbH) structural domain.	4.35396e-83
CP032698.1|AYG84217.1|7168495_7169152_+|putative-membrane-protein	gnl|CDD|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	4.51393e-41
CP032698.1|AYG84214.1|7164111_7165143_-|hypothetical-protein	gnl|CDD|370676	pfam09770, PAT1, Topoisomerase II-associated protein PAT1. Members of this family are necessary for accurate chromosome transmission during cell division.	2.24816e-06

Protein sequences

>CP032698.1|AYG84211.1|7160307_7161498_+|Elongation-factor-Tu
MPKTAYVRTKPHLNIGTMGHVDHGKTTLTAAITKVLAEREGGTTTRYVSFDRIDRAPEEAARGITINIAHVEYETDTRHYAHVDMPGHADYVKNMVTGAAQLDGAILVVSALDGIMPQTAEHVLLARQVGVDHIVVALNKADAVDDGEDAVLTDLVELEVRELLSAHGYGGDGVPVVRVSGLKALEGEPRWTEAIGALLDAVDTYVPLPERYVDAPFLLPVENVLTITGRGTVVTGAVERGTVRVGDRVRVLGAEVESVVIGLETFGKPMDSAQAGDNVALLLRGVARDAVRRGHVVAEPGSVTPSRRFTAQVYVLSTREGGRATPIATGYRPQFYIRTADVVGDVDLGELAVARPGDTVTMTVELGRDMALEPGLGFAIREGGRTVGAGTIATLL
>CP032698.1|AYG84210.1|7159315_7160014_+|hypothetical-protein
MTPRAPHSPLADDVLARLVRVYPEGGDPHRAGEMVAYMKGVAPFLGIRSPERRALSRTVLDGLAKPAEADCAAVALRCWALEEREYHYFAVDYLRRYVRVCSSAFLPVARHLVVTTSWWDTVDHLAAHVVGPLVAADAELAGVMDRWIDDDDLWLARTALLHQLTYKERTDANRLFDYCLRRAAHPDFFIRKAIGWSLREYAKSDPGAVRAFVAAEGERLSPLSVREALKNL
>CP032698.1|AYG84209.1|7158444_7159149_-|TVP38/TMEM64-family-inner-membrane-protein-YdjZ
MFQPAARSTSGLAARCGRALLSPWSRLTLLVVVLAAAGSAVLVLQPQRLLADGWPPQLGGAGAVALFALAYGLCAAAFVPRPILNLAAGALFATSAGFVSSLVGTVLGAGIAFGLGRVLGQDALRPLVRGRWLKAADGQLSRHGFRSMMAIRLFPGVPFAAANYCAAVSRMGWAPFLLATGLGSVPNTLAYVVAGGSASSPTSPAFLIAMGFIVLSGAAAATVAWRKRQALRKR
>CP032698.1|AYG84208.1|7157330_7158320_-|Undecaprenyl-diphosphatase
MPLDPREITGGPTAAPGFRRVLGVPNGRDPDPPWMAQHPMSWFESFILGLVQGLTEFLPISSSAHLRLTAAFAGWQDPGPAFTAITQIGTETAVLIYFRSDIARIVSAWFRSLTDRSLRADPDARMGWLVIVGSIPIGVLGIVLKHQIDTSFRDLRVIATTLVAMGVVLGIADRLAARDESGGRHRAARERKSLRELGTRDGLIYGICQAMALIPGVSRSGATISGGLLMGYTCEAAARYSFLLAVPAVLASGVFELKDAGGPGQAPLLPTLVAAVIAFAVGYAVIAWFMTFISTKSFMPFVVYRIVLGIALFVLIAVGTLAPDAGGGL
>CP032698.1|AYG84207.1|7156922_7157300_+|hypothetical-protein
MEQSEVLKRVIGILTEAGDYRRRIEQDEERGSRNTEIGIVTALLNETMPHIEIPADATPQEMATLVAREVGGAIQQLVAAFSLAFVALAQVHDSGEQDVSSADVLQDLALRAEEAKGDGPQTSRE
>CP032698.1|AYG84206.1|7156525_7156702_-|hypothetical-protein
MPPTYDCRSLRPADVVNAEIRSLWEQSDGRLSPDEEERYHGLLVEWAAAVRDNTAQAA
>CP032698.1|AYG84205.1|7156211_7156409_-|hypothetical-protein
MSSSSERPGPTPSDADAANDAIRALVDGADGQWPAEEYERLLADWAAAVGETTPLAAGAVSKPRT
>CP032698.1|AYG84204.1|7155246_7156047_-|hypothetical-protein
MHTDAPAGAPDDELLAVFDRQMRQHALPDGPGATVERSGDVLRQVGPAPVWNGILWSDLTASSADAEIAAQVRHFAALGNEFEWKLYAHDRPSDLGLRLAAAGFEAEPEETVMVARVADLPLDVEPPAGITLRPVVDEAGVALMTRVHDGAFGPGSARVGERLLAQFIQAPETVTAVVAMAGEVPVSAARMEVHPGTEFASLWGGGTLPEWRGRGIYRALIAYRTRVAAERGCRYLQVDASDRSRPILRRLGFVPLTLTTPYIRRA
>CP032698.1|AYG84203.1|7154400_7155222_+|Short-chain-enoyl-CoA-hydratase
MWLVDASCYRWRMTDETTPAVRSERNGPVTTVILSRPRARNAVDGPTARALAEAFRAFEADERAAVAVLWGEGGTFCAGADLKAIGTERGNTVTEDSDGPMGPTRLRLSKPVIAAVAGHAVAGGLELALWCDLRVMEEDAVFGVFCRRWGVPLIDGGTVRLPRLIGAGRAMDLVLTGRPVDAAEAHAIGLADRVVPPTTARARAERLAAEIAAFPQTCLRHDRMSLLEQEGLGETEALLGEVRHGVHALAEAAEGAARFAAGAGRHGTFDNTA
>CP032698.1|AYG84202.1|7153874_7154354_-|hypothetical-protein
MTQRVDLGTLLDRLAIDELITGYAAAVDDGDWAAYRALFAPDGRADYGAAGGIAGSVEEVARWLAETLRLFPVRQHLITNRLLTLQDLGGYPGDRAELRADYLNPMCFGGDGDGAPSAPDFESGGRYAFSLLRTEAGWRLSSVTVHEKWRRMSGALAGG
>CP032698.1|AYG84212.1|7161915_7162776_+|Polyamine-aminopropyltransferase
MNDDHRSAPIPVTRDVDQGTAKLLPDIDRERAWLLTVNGAPQSYVDLDDPTYIEFEYVRRLAHVVDCAAEEGAPLDVLHLGGGALTLPRYVAATRPGSRQDVVEADRALLQLVREKLPLAPGIGVTPHAADARAWAQAAPAASVDLLIADVFGGSRVPAHLTSVEYARVAERVLKPEGIYAANLADGAPFTFLRSQLATFQAVFAEVALIAEPSVLRGRRFGNAVLLASRHPLDVAALARRTAGDAFPARVEHGDALRRFIAQAPMVDDTAARPSPEPPEGAFGIG
>CP032698.1|AYG84213.1|7162737_7164054_-|hypothetical-protein
MTSAAIPPPARTSPPARRPSWAGRNYTLLTAAAIVTNLGSQGALIAAAFAVLSSGGDAGDVGLVAAARTVPLVLFLLVGGALADRLPRHRVMVAANTLNFLSQGAFALLVLTGDPRLWQMMVLTALGGVGQAFFGPASEGMLMSSVSGVEAGRAFAFYRMAMHGAGIGGAALGGALIAAFGPGWVLAIDAAAFAVAGALRAFLDVSHIPARSAGGGMVSDLREGWREFVTRPWLWAIVVQFAVVNAVVAAAEAVYGPLVARDELGGPGPWGLALAAFGAGTVAGAFLMMRWKPRRLLLAGSLCVFPLALPSAALAVPLPVAGLAAVMLLTGVSIEVFGVSWMTALNQEIPEEKLSRVSAYDWLGSIAMVPVATALAGPAQNAVGRTSALWGCSALIVLLTAAVLCVPDVRRLTRRGEPVALAGPAASADAEGALGRLG
>CP032698.1|AYG84214.1|7164111_7165143_-|hypothetical-protein
MWPGQQPPGGEQNPQDPNQNPYQQPGYQQPNPYQQPGQQPPGYPPQGYQTPNPYQQPTVPQYPVAGPPGPPQPPQNNDKKKTTIIAIVAATAVVVAAAVTGVVVLKDDDKGTPQADGKNTKSPSAPASDSAAPSSPAPNPRGAGAAVQPVIAGWKVVVNPAKGDAFDVPPDWEVDSPTMSTGWSDDADPNGFGGMTMSAPAYYKSKWCTTKSSSGRDVSTRLVTVGTKGANGAKDTGEAAEQADDWLYFAYTQPDKDHITGEKPVPYTTKSGLQGSVARAKTTGVKKTDKCSTEGQSVLFGFKTAKGDLAAWSLIANTGVPDAVSEDTIQKILSTIRLVPATS
>CP032698.1|AYG84215.1|7165252_7165690_+|hypothetical-protein
MSVGEMLTATVPMARTLELEFLETTPERAVVRLPDRAEYHNHLGGPHAGAMFTLAESASGAIVIAAFGDQMHRAVPLAVKAEIGYKKLAKGVVTATATLGRPIADVVADLDAGQRPEFPVVIEIQRADGAVTGEMTVVWTLRPNS
>CP032698.1|AYG84216.1|7165942_7168420_+|Thermostable-beta-glucosidase-B
MSDTVSRRAALRLLAGAATVAAAATGDFTASARPRTDAPGSRRTEALLGRLTLDEKIGLLHGSEDPHGLGQAGYLPGVPRLRIPPLRLADGPAGVRVTAHATALPAPVMLAATFDPALAREYGEVIGREGRALGQDVLLSPMVNLIRTPYAGRNFETFSEDPLLSADLVAEEIHGIQSQGLIATVKHFALNNQEKDRLTLDARIAEQPLRELELRGFEAAVAAGVGAVMGAYNKVNGAFACENKPILTDVLRTDWGFEGWVMTDWFATHGLAALAAGLDMEMPAGVHFADTLKAAVLDGSVPEALVDRAVRRVLSVMERFGLLDGSAPARPARDARRGARTALTVARAGATLLHNRHATLPLAGAAARHIAVIGPTAVIPFVSGGGSAHVVPDHARRPLDALRDRAGDGARVCHTLGEDLYGKPLPGTSPGADFEGQHVDPGATWTYDGTLTVTEDDEWTFCIHYSGDRPKVVLDGTELFPPAPGLGELFGGGLVGTAPDGLAVRRATLTLAAGAHRLVITAKGREAGQLFRLRRVTGATRAADVAAAVRAARAASSVVLFAYEDATEGADRTHLALPGHQNELIEAVAAVNSRTTVVLNTSSCTTMPWLGRVGAVLQMYYPGQEGADATAAVLFGECDPGGRLTQTFPVSEDRHPMAGDPRRYPGVDGTEEYSEGLRPGYRWYDAEGVSPLFPFGHGLSYTTFAYTDLSVRPDGDGLAVAFTVRNTGHRTGVTVAQVYLGPSPDLGLDQVRRALAGYRRLELEPGHDRRVTVRVGARSLSSWDPERHAWVLGTGRREVSVGVSAGETLLVGHGSVAARPPAGRP
>CP032698.1|AYG84217.1|7168495_7169152_+|putative-membrane-protein
MHIQEWLEHIPAVSVYLLVALVIGVESLGIPLPGEIVLVSSALLASQQGHINPVVLGACATAGAVIGDSIGYAIGRKGGRPLLAWLGRKFPKHFSEGHVAMAERSFQKWGMWAVFFGRFIALLRIFAGPLAGVLHMPYWKFLIANVLGGICWAGGTTAVIYYLGIVAESWLKNFSYLGLVAALLIGVASMLVVKNRAKKSMAEAEAAQSTPENVPAGD
>CP032698.1|AYG84218.1|7169199_7169643_-|hypothetical-protein
MALFRIDRRTELTPAEAWHRLTDWERHGEGVPFTRITVRTPPPTGPGTVFVARTGLGRLAFADPMEITRWRPPSEGRPGVCRLEKRGRVITGWAEIEVAASGAGALVVWREELRVRGLPRALDPLTAAAGRLVFGRALTVLLRDRTP
>CP032698.1|AYG84219.1|7169738_7170269_+|2,3,4,5-tetrahydropyridine-2,6-dicarboxylate-N-acetyltransferase
MAEQALVVAVGGKAPEIAPTAFTAPTSVVLGEVTLGAGASVWYHAVLRADCGPIVIGAESNIQDNCTVHVDPGFPVILGERVTVGHNAVLHGCTVEDDVLVGMGATILNGARIGAGSLIAAHALVPQGMVVPPGSLVAGVPAKVRRELSEEEREGIKVNALMYLGLAEDHRAAHAG
>CP032698.1|AYG84220.1|7170340_7171084_+|Putative-acetyltransferase
MPKNRNTFSSLTAWRREIASRAVHGGWDWIKRTGAVTAEHPGRLRFRRIGAGTRLAFPQGTVFGEPWIELGDHCIIGEQVTLTAGMMPGLDLGTEPILTLGNGVVLGRGSHVIADTTITIGSDTYCGPNVYITSTNHSYDDPRQPVGKQWPRMEPVEIGPGCWLGTGAVVLPGARLGRNVVVAAGAVVRGEVPDHAVVAGAPAKIVRTWDERDGWQPPLRTPAPVPIPDGVTPEQLLAIAELSPEEA
>CP032698.1|AYG84221.1|7171164_7172031_-|hypothetical-protein
MTALFALATSLLWGLADFGGGLLTRRMPALTVVVASQTVAVVVLGSVVLATGGLREAAPQLWFAVAAGAVGPVAMLSFYKALALGPMGVVSPLGSLGVAVPVGVGLALGERPGLLQFAGIAVAVAGVLLAGGPEFRGAAVQRQAVLLTLLAAFGFGAVMALISEASTTVTGLFLALFVQRVTNVAVGGTALLVSVRRGGAALPADGGSRAVWLALPALAFVGLADVAANGTYAIAAQRGPVTVAAVLASLYPVVTALAARGVLKERLRTVQAAGAGLALVGTVLLATG

Crispr_ID: CP032698_95

• CRISPR_ID: CP032698_95
• CRISPR_location: 7390231-7390486
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of CP032698_95

Consensus_repeat	Method
TTCAGGGGCGCGGGGAACTGCGCGA	PILER-CR
AGGGGCGCGGGGAACTGCGCGA	CRT

spacers of CP032698_95

>95.1|7390256|34|CP032698|PILER-CR
CCAGCCCCGCACGGTCCGCGGACGAATGCGGGTT
>95.2|7390315|32|CP032698|PILER-CR
GAAGCGGGCACGGCCCGCACCCGGCCGAGGCA
>95.3|7390372|34|CP032698|PILER-CR
CCAGCCACGCACGGCTGGCAGCCGAAAACGGGTT
>95.4|7390431|31|CP032698|PILER-CR
GAAGTGGGCACGGGCCGCAGGCGGCCGGGGA
>95.5|7390256|37|CP032698|CRT
CCAGCCCCGCACGGTCCGCGGACGAATGCGGGTTTCC
>95.6|7390315|35|CP032698|CRT
GAAGCGGGCACGGCCCGCACCCGGCCGAGGCATTT
>95.7|7390372|37|CP032698|CRT
CCAGCCACGCACGGCTGGCAGCCGAAAACGGGTTTTC
>95.8|7390431|34|CP032698|CRT
GAAGTGGGCACGGGCCGCAGGCGGCCGGGGATTC

CRISPR arrays and Neighbor proteins around CP032698_95

CRISPR arrays

The CRISPR arrays of CP032698_95

>merge|CP032698|95|7390231-7390486|PILER-CR,CRT
TTAAGGGGCGCGGGGAACTGCGCGACCAGCCCCGCACGGTCCGCGGACGAATGCGGGTTTCCAGGGGCGCGAGGAACTGCGCGAGAAGCGGGCACGGCCCGCACCCGGCCGAGGCATTTAGGGGCGCGGGGAACTGCGCGACCAGCCACGCACGGCTGGCAGCCGAAAACGGGTTTTCAGGGGCGCGGGGAGCTGCGCGAGAAGTGGGCACGGGCCGCAGGCGGCCGGGGATTCAGGGGCGCGGGGAACTGCGCGG

>CP032698|95|25|7390231-7390486|PILER-CR
TTAAGGGGCGCGGGGAACTGCGCGA	CCAGCCCCGCACGGTCCGCGGACGAATGCGGGTT
TCCAGGGGCGCGAGGAACTGCGCGA	GAAGCGGGCACGGCCCGCACCCGGCCGAGGCA
TTTAGGGGCGCGGGGAACTGCGCGA	CCAGCCACGCACGGCTGGCAGCCGAAAACGGGTT
TTCAGGGGCGCGGGGAGCTGCGCGA	GAAGTGGGCACGGGCCGCAGGCGGCCGGGGA
TTCAGGGGCGCGGGGAACTGCGCGG

>CP032698|95|12|7390234-7390486|CRT
AGGGGCGCGGGGAACTGCGCGA	CCAGCCCCGCACGGTCCGCGGACGAATGCGGGTTTCC
AGGGGCGCGAGGAACTGCGCGA	GAAGCGGGCACGGCCCGCACCCGGCCGAGGCATTT
AGGGGCGCGGGGAACTGCGCGA	CCAGCCACGCACGGCTGGCAGCCGAAAACGGGTTTTC
AGGGGCGCGGGGAGCTGCGCGA	GAAGTGGGCACGGGCCGCAGGCGGCCGGGGATTC
AGGGGCGCGGGGAACTGCGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG84429.1|7397632_7398145_-|hypothetical-protein	unknown	unknown	gnl|CDD|187759
CP032698.1|AYG84415.1|7385103_7385667_+|HTH-type-transcriptional-regulator-PuuR	unknown	unknown	gnl|CDD|197775
CP032698.1|AYG84424.1|7393787_7395029_-|Threonine--tRNA-ligase-1	unknown	unknown	gnl|CDD|237050
CP032698.1|AYG84412.1|7380508_7382422_-|hypothetical-protein	unknown	unknown	gnl|CDD|367001
CP032698.1|AYG84419.1|7389045_7389837_-|N-acetyl-alpha-D-glucosaminyl-L-malate-deacetylase-1	unknown	unknown	gnl|CDD|225031
CP032698.1|AYG84428.1|7397197_7397557_-|hypothetical-protein	unknown	unknown	gnl|CDD|187759
CP032698.1|AYG84416.1|7385756_7386191_-|hypothetical-protein	unknown	unknown	gnl|CDD|197670
CP032698.1|AYG84422.1|7391516_7392557_-|PEP-dependent-dihydroxyacetone-kinase,-dihydroxyacetone-binding-subunit-DhaK	unknown	unknown	gnl|CDD|237724
CP032698.1|AYG84420.1|7390491_7390716_-|hypothetical-protein	unknown	unknown	gnl|CDD|183108
CP032698.1|AYG84417.1|7386317_7386908_-|hypothetical-protein	unknown	unknown	gnl|CDD|378427
CP032698.1|AYG84410.1|7379065_7379470_-|hypothetical-protein	unknown	unknown	gnl|CDD|380093
CP032698.1|AYG84414.1|7383831_7384968_-|hypothetical-protein	unknown	unknown	gnl|CDD|368677
CP032698.1|AYG84413.1|7382503_7383835_-|Uric-acid-permease-PucK	unknown	unknown	gnl|CDD|274468
CP032698.1|AYG84426.1|7395545_7396061_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84423.1|7392622_7393513_-|Glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl|CDD|176543
CP032698.1|AYG84427.1|7396244_7397201_+|Epimerase-family-protein	unknown	unknown	gnl|CDD|187553
CP032698.1|AYG84418.1|7386933_7388955_-|2,4-dienoyl-CoA-reductase-[NADPH]	unknown	unknown	gnl|CDD|239240
CP032698.1|AYG84425.1|7395277_7395526_-|50S-ribosomal-protein-L31-type-B	unknown	unknown	gnl|CDD|234969
CP032698.1|AYG84421.1|7390897_7391494_-|PEP-dependent-dihydroxyacetone-kinase,-ADP-binding-subunit-DhaL	unknown	unknown	gnl|CDD|274099
CP032698.1|AYG84411.1|7379560_7380337_-|hypothetical-protein	unknown	unknown	gnl|CDD|378940

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG84429.1|7397632_7398145_-|hypothetical-protein	gnl|CDD|187759	cd09319, TDT_like_1, The Tellurite-resistance/Dicarboxylate Transporter (TDT) family. The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes members from all three kingdoms, but only three members of the family have been functionally characterized: the TehA protein of E. coli functioning as a tellurite-resistance uptake permease, the Mae1 protein of S. pombe functioning in the uptake of malate and other dicarboxylates, and the sulfite efflux pump (SSU1) of Saccharomyces cerevisiae. In plants, the plasma membrane protein SLAC1 (Slow Anion Channel-Associated 1), which is preferentially expressed in guard cells, encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. SLAC1 is essential in mediating stomatal responses to physiological and stress stimuli. Members of the TDT family exhibit 10 putative transmembrane alpha-helical spanners (TMSs).	1.20221e-25
CP032698.1|AYG84415.1|7385103_7385667_+|HTH-type-transcriptional-regulator-PuuR	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	1.47872e-12
CP032698.1|AYG84424.1|7393787_7395029_-|Threonine--tRNA-ligase-1	gnl|CDD|237050	PRK12305, thrS, threonyl-tRNA synthetase; Reviewed.	0
CP032698.1|AYG84412.1|7380508_7382422_-|hypothetical-protein	gnl|CDD|367001	pfam02254, TrkA_N, TrkA-N domain. This domain is found in a wide variety of proteins. These protein include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD.	5.22174e-20
CP032698.1|AYG84419.1|7389045_7389837_-|N-acetyl-alpha-D-glucosaminyl-L-malate-deacetylase-1	gnl|CDD|225031	COG2120, COG2120, Uncharacterized proteins, LmbE homologs [Function unknown].	5.5729e-34
CP032698.1|AYG84428.1|7397197_7397557_-|hypothetical-protein	gnl|CDD|187759	cd09319, TDT_like_1, The Tellurite-resistance/Dicarboxylate Transporter (TDT) family. The Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes members from all three kingdoms, but only three members of the family have been functionally characterized: the TehA protein of E. coli functioning as a tellurite-resistance uptake permease, the Mae1 protein of S. pombe functioning in the uptake of malate and other dicarboxylates, and the sulfite efflux pump (SSU1) of Saccharomyces cerevisiae. In plants, the plasma membrane protein SLAC1 (Slow Anion Channel-Associated 1), which is preferentially expressed in guard cells, encodes a distant homolog of fungal and bacterial dicarboxylate/malic acid transport proteins. SLAC1 is essential in mediating stomatal responses to physiological and stress stimuli. Members of the TDT family exhibit 10 putative transmembrane alpha-helical spanners (TMSs).	5.77315e-15
CP032698.1|AYG84416.1|7385756_7386191_-|hypothetical-protein	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.39553e-14
CP032698.1|AYG84422.1|7391516_7392557_-|PEP-dependent-dihydroxyacetone-kinase,-dihydroxyacetone-binding-subunit-DhaK	gnl|CDD|237724	PRK14481, PRK14481, dihydroxyacetone kinase subunit DhaK; Provisional.	0
CP032698.1|AYG84420.1|7390491_7390716_-|hypothetical-protein	gnl|CDD|183108	PRK11377, PRK11377, dihydroxyacetone kinase subunit M; Provisional.	7.70383e-10
CP032698.1|AYG84417.1|7386317_7386908_-|hypothetical-protein	gnl|CDD|378427	pfam10400, Vir_act_alpha_C, Virulence activator alpha C-term. This structure is homo-dimeric, and the domain here is the C-terminal half of the structure, often associated with PadR upstream, (pfam03551), which is a transcriptional regulator.	1.96453e-21
CP032698.1|AYG84410.1|7379065_7379470_-|hypothetical-protein	gnl|CDD|380093	pfam18029, Glyoxalase_6, Glyoxalase-like domain. This entry comprises a diverse set of domains related to the Glyoxalase domain. The exact specificity of these proteins is uncertain.	1.76472e-14
CP032698.1|AYG84414.1|7383831_7384968_-|hypothetical-protein	gnl|CDD|368677	pfam05935, Arylsulfotrans, Arylsulfotransferase (ASST). This family consists of several bacterial Arylsulfotransferase proteins. Arylsulfotransferase (ASST) transfers a sulfate group from phenolic sulfate esters to a phenolic acceptor substrate.	8.54459e-24
CP032698.1|AYG84413.1|7382503_7383835_-|Uric-acid-permease-PucK	gnl|CDD|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	1.03294e-96
CP032698.1|AYG84423.1|7392622_7393513_-|Glycerophosphodiester-phosphodiesterase	gnl|CDD|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	3.58335e-64
CP032698.1|AYG84427.1|7396244_7397201_+|Epimerase-family-protein	gnl|CDD|187553	cd05242, SDR_a8, atypical (a) SDRs, subgroup 8. This subgroup contains atypical SDRs of unknown function. Proteins in this subgroup have a glycine-rich NAD(P)-binding motif consensus that resembles that of the extended SDRs, (GXXGXXG or GGXGXXG), but lacks the characteristic active site residues of the SDRs. A Cys often replaces the usual Lys of the YXXXK active site motif, while the upstream Ser is generally present and Arg replaces the usual Asn. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.68151e-118
CP032698.1|AYG84418.1|7386933_7388955_-|2,4-dienoyl-CoA-reductase-[NADPH]	gnl|CDD|239240	cd02930, DCR_FMN, 2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the flavin and iron-sulfur cofactors. Metabolism of unsaturated fatty acids requires auxiliary enzymes in addition to those used in b-oxidation. After a given number of cycles through the b-oxidation pathway, those unsaturated fatty acyl-CoAs with double bonds at even-numbered carbon positions contain 2-trans, 4-cis double bonds that can not be modified by enoyl-CoA hydratase. DCR utilizes NADPH to remove the C4-C5 double bond. DCR can catalyze the reduction of both natural fatty acids with cis double bonds, as well as substrates containing trans double bonds. The reaction is initiated by hybrid transfer from NADPH to FAD, which in turn transfers electrons, one at a time, to FMN via the 4Fe-4S cluster. The fully reduced FMN provides a hydrid ion to the C5 atom of substrate, and Tyr and His are proposed to form a catalytic dyad that protonates the C4 atom of the substrate and completes the reaction.	0
CP032698.1|AYG84425.1|7395277_7395526_-|50S-ribosomal-protein-L31-type-B	gnl|CDD|234969	PRK01678, rpmE2, type B 50S ribosomal protein L31.	7.48014e-46
CP032698.1|AYG84421.1|7390897_7391494_-|PEP-dependent-dihydroxyacetone-kinase,-ADP-binding-subunit-DhaL	gnl|CDD|274099	TIGR02365, dha_L_ycgS, dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.	2.32817e-71
CP032698.1|AYG84411.1|7379560_7380337_-|hypothetical-protein	gnl|CDD|378940	pfam12746, GNAT_acetyltran, GNAT acetyltransferase. Many of the members are annotated s being Zwittermicin A resistance proteins, whereas others are listed as being GNAT acetyltransferases. The family has similarities to the GNAT acetyltransferase family.	3.58184e-07

Protein sequences

>CP032698.1|AYG84419.1|7389045_7389837_-|N-acetyl-alpha-D-glucosaminyl-L-malate-deacetylase-1
MSAFNDIGGTTPPHLPHLPEDWTRCLAVVAHPDDIEYGTASAVARWTAQGKQVGYLLATRGEAGIDGIHPDRAAPLREAEERAGAREVGVSDVEFLGHRDGVVAYGTELRRDIVRAIRRFRPDVMVSGAYTIRMIGGLVNQADHRAVGLAALDAARDAGNRWIFPELADEGLEPWPGVRFVAFAGPERPTHGVDVTGEPLERGIASLTAHAEYTKGLGAEAGNFEPRPFLTWIARSSGPALGVEAAVLFDVHQLAPEGPPPWV
>CP032698.1|AYG84418.1|7386933_7388955_-|2,4-dienoyl-CoA-reductase-[NADPH]
MTAYPHLLSPLDLGFTTLPNRVLMGSMHVGLEEAENGFERMAAFYAERARGGVGLIVTGGIAPNDAGRPYPGGARLTTEAEAAQHRVVTEAVHREGGRIAMQILHFGRYAYHEDLVAPSALQAPISPFVPNALSDDEVEATVEDFVRAAGLARDAGYDGVEIMGSEGYLINEFIVGATNRRTDRWGGSYENRMRFPVKIVRRTRERLGPDFIIIYRLSMLDLVPGGSTLDEVVTLARAVESAGATIINTGIGWHEARIPTIATSVPRGAYTWVTQKLMGSVSIPLITSNRINTPDVAEQLLAEGRADMVSMARPFLADPEFVAKARAGRAETINTCIGCNQACLDHTFSGRITSCLVNPRACHETELVLSPTRLRKRLAVVGAGPAGLAFAVSAAGRGHAVTLFDAADRIGGQLNIAKRVPGKEEFDETLRYYRTQLELLGVDVRLNTEVTAANLSDGAYDEIVIATGVTPRTPEIPGSDHPSVVSYLDVLRDGAPVGERVAVVGAGGIGFDVAEFLTDGGDAASLDPETYFRQWGVDTTYGERGGLRGAERPKPPRQVHLLQRKTTKVGAGLGKTTGWIHRTELKHRGVTMVPGVRYDRIDDEGLHITVDGVSSVLPVDTVVLCAGQESRRGLYEELSASGATVHLIGGADVAAELDAKRAIDQGTRLAAAL
>CP032698.1|AYG84417.1|7386317_7386908_-|hypothetical-protein
MSLPHAILTALLEKPSSGLELTRRFDKSIGYFWSATHQQIYRELGKLEQRGLIRALPGAAPARGQKKRYEVLPAGRAELAQWAAAGQDPKPMRDPLLVRMRAAAVIGTGGLRAELERHLALHRAQLATYSGIESKDFPPGRNGENQDGENGHGEDRNGEQDRLRHLVLRGGIELESFWIGWLTEALDALGEEPPGA
>CP032698.1|AYG84416.1|7385756_7386191_-|hypothetical-protein
MLSRDRSVVTIQRELTAFARRARAAAARMHPELSLVSFTLLSHLEDQQGCRATDLAAYYMLDKSTISRQIAGLEKLGFVERISDPDDHRIQVLRLTPAGTAKLAEAAELRRQAFHERLADWAPEDLDRFAEYLLRYNSLAENGG
>CP032698.1|AYG84415.1|7385103_7385667_+|HTH-type-transcriptional-regulator-PuuR
MNDTGGTGAGPRLGGAVRRRRRALDLTLATVAERSGLSVPFLSQIENDRARPSMRSLQRIADALGTTAVELLAAADARDRAVDVVRADDDAGLSADAGVRPLVRGRHQMHALEFTGERAADREFLHHNDELMYIADGAAEVDADGRGYLLSRGDTLYLTGGVRHRWRATLPGTRVLVVAVSDHIEGI
>CP032698.1|AYG84414.1|7383831_7384968_-|hypothetical-protein
MTARPTAVDQNQRRRRGTGLIALDPGAACPGFTLYAPLTGGGEVYLVDLRGDAVHTWHLPYRPGRHARILGNGNLAYNGVLPGQKALFPMWHKYRGGVMLEVTPDGTTVREHLDPLQHHDAHHLDDGRILYTGLEPLRGAEAAAVRGGVAGSEAAGGTVWADTIKEVAPDGTELWSWRAADHLDRAEYALHPDYAREHWPLINSVTPLADGNVLASLRSVSAVVVISRDTGEILWRTHPGTVSQQHHPTELADGNLLVFDNGVFRPGHDVPYSRVIEIERAGGEVVWEYHDPARESFFAPFMGSAQRLPNGNTLITDSPAGRLFEVTQQGYLCWEFVVPQFGGYEESEVRTLFPAEPNAVFRAHRYAAEELPWLEARP
>CP032698.1|AYG84413.1|7382503_7383835_-|Uric-acid-permease-PucK
MTSPVDERVPFGRLVPLALQHVLAMVAAPVSTVFLTAGALRLPPDRTASLLSAVLVLCGAGSLLQSLGVRTFGARLPFVMLPGGAAAALFLGIARDHGPAVASGSVLLAAALLLAVTPLYARLVRFFPPLVMGVTVLLIGISMVKVAAQLVTGPGAPAAPRAVALAAVTVAATVLAHLVLRGVWRRTAVLIGMVAGTLVAVTTGLGAFTPAPSSGFSLPALFPYGAPRFDPVAALPLLVFSLTTLAEITGQTVLSSETVGRAPDPGRDVPRVARADALVSLVGGLFGTSLMVTSAENIGIGRLTGVRSRYVTAAAGGLLVLAGLLSPLSRLVAGLPAAVVGGSALVVYSVIAVMGVEMLGRAGLGERSNSLVAALALAVGLLPLLAPGLYDGFPGWVRTVAGSGVVAGTIAAVLVHALFTTPVTHRGVQPPRPEPAARRRGAT
>CP032698.1|AYG84412.1|7380508_7382422_-|hypothetical-protein
MVVSGDGALAHRLAGELREVYGEHVVLVVPPDSGARSARLPANGRTRASALFGRMSSVMLRSPAPGPDGAGEGGLVEAVEPSDEALTQAGIERAAALALVHRDDETNIRAALIARRLNPRVRLVIRLYNRKLGQYLQELLDQAAALAAPDGPGPTEAETSTTVLSDADTAAPALAATALAGTSKVVHADGVLLRAGQRPPPRPGEVADPGLCTLALLSSTTNDPAGAEGSDHSGSEGPRLLPDERSMDEGGHRGRVVLETVTYTGPAQPPGRLTDLGAPLGRLFSRRLRWSLAGVVASVVALAVATWLTTGDDPLHAAYLTLLDIFAIDDPAIGQPVERQILQLLSGLTGLLLLPVLIAAVLEGLGTFRNASALPRPPRGLSGHVVLLGMGKIGARVLVRLRELDIPVVCVEADPEARGIALARRLRVPTVIGDVTQEGLLESARIHRAHALLALTSSDTTNLEAALYARSVKPDLRVVMRLYDDDFATAVHRTLRAAHPQALTRSRSVSHLAAPAFASAMMGRQILGAIPVERTVLLFAAVDVAGHPQLEGRTVEDAFREGAWRVLALDTSSPDDRVPDLGAARRGRSGTPGDLVWQVPPGYVLRPEDRVVLAATRRGLAELLGRRPSSRVPQRPH
>CP032698.1|AYG84411.1|7379560_7380337_-|hypothetical-protein
MIELSSRQLAAHTHLLGDCEPGPAALAEHVLSTGNGRALADRADHPRTLALDCAGHVLLRGDPDALGPTDLAPFAHRRVEAPARFLPALDVAFDRVVPSERMVYVRQQAAAAPRPPRGVTIRPLTSSDAPSLVRLPAESAWIHASWGGPSGLCRSGHAWGAFRQGRLLAIACTYFRGGAHEEIAVVAAPGRRHQRLALNCVLALDGDVAARGRTATLTCSRHDRPGRLLAWTAGFRLVREYVHYATGAYVAHGARVPV
>CP032698.1|AYG84410.1|7379065_7379470_-|hypothetical-protein
MSVSKTSILVLDCAEPIELAEFYAKLLGGEIRTACDPDFVEIVGTDGVHMAIRRDHGYAPPSWPRPDDSQQAHLRIVVEYGDMDAAEREAITLGAMPVDTKDNNGIRDERVYADPAGHSFTLAVWAKRSEQSES
>CP032698.1|AYG84420.1|7390491_7390716_-|hypothetical-protein
MDRGAGVAVLVDLGSAVLTVKALLAEGDELPTGTRLLDAPFVEGAVAAVVSASAGAGLEAVVAAAAEARTYRKT
>CP032698.1|AYG84421.1|7390897_7391494_-|PEP-dependent-dihydroxyacetone-kinase,-ADP-binding-subunit-DhaL
MLDAAFMCRWMSVTAAAVDREAARLTDLDSAIGDADHGANLRRGFTTVTEVLTKETPDTPGAVLALAGRQLISTVGGASGPLYGTLLRRAGKALGDATEVDRERLAEALGAGVAAVAQLGGAAAGDKTMLDALLPAVEALGASFAAAAEAADAGALATVPLRARKGRASYLGERSVGHQDPGATSAALLMGALAEAAA
>CP032698.1|AYG84422.1|7391516_7392557_-|PEP-dependent-dihydroxyacetone-kinase,-dihydroxyacetone-binding-subunit-DhaK
MILGPSHFARLALEVMVNMLINVPETVVADALRGIAAAHPSLTVDVENRVVVRRDAPVAGQVGLVSGGGSGHEPLHAGFVGPGMLSAACPGEVFTSPVPDQMVRAAAAVDGGAGVLFVVKNYTGDVLNFDMAAELAEDEGVVIAKVLVDDDVAVNDSLYTAGRRGTGATLFVEKIAGAAAAEGAPLERVEAIARQVNASARSFGVALTACTTPAKGSPTFELPPGELELGVGIHGEPGRERRAMMTSREIADYAVQVVLDELRPTSPVLLLVNGMGATPLLELYGFNAEVHRVLAERGVPVARTLVGNYVTSLDMAGCSVTLCQVDEELLRLWDAPVDTPALRWGR
>CP032698.1|AYG84423.1|7392622_7393513_-|Glycerophosphodiester-phosphodiesterase
MRRRTALSTVATTLCGALALALPAPAAQARAAGPVTVYGHRGAAAYAPENTLSSVQRAADLGAHWVENDVQRTRDGALVVIHDTTLERTTDAKRRYPGRSPWSVGSFTLAEIKTLDAGGWFAPRFRGERVPTLAEYLRRLDRTGQGLLLELKRPELYPGIEGQTLRALARAGWLDGPHIARRLVVQSFSAPALRTTHRLRPAVRTGFLGNPPVSQLKRYAAFADQINPEQRTVTSAYVKAVHATPGPHRAPMRVNAWTVDSGPAAARLVGLGVNGVITNRPDVIAKATRRIRPGTA
>CP032698.1|AYG84424.1|7393787_7395029_-|Threonine--tRNA-ligase-1
MHDHRRLGRELDLFDTDPLMGAGLPYWLPNGAAVRHALEEYVRETERLAGYRHVYSPVLGKRELYEISGHWSHYSEDMFPPMELGAEQVVLRPSLCPHHALIYRSRAHSYRELPLRMAELGGMYRSEPSGVLGGLTRVRAIQLNDAHVFCTLDQAAEEARAALDLIGRAYEALGIRPARYRLSLPGSGDKYVADAGMWERAAALLTEVLDASGVPYEAVEGEAAFYGPKIDVQIADASGREATLSTVQIDFHQPEQFDLHYIGPDGARHRPVMVHRSIIGSMERAVAHLIELHGGAFPAWLAPVQLVVAPVSDAQVEAGAALVERALAEGLRAELAGPEQGSLGARIRAARLVPYQAVIGAREDAAGEVALRLRDGRHPAALATAELLRRVGALVSSRSAQLWDHQGELAASG
>CP032698.1|AYG84425.1|7395277_7395526_-|50S-ribosomal-protein-L31-type-B
MQRDKQPPYQPVVFRDRAAGFAFLTRSTATSDETIDWDDGNTYPVIDVEISAESHPFYTGKARTVDTEGRIARFERRYEGKE
>CP032698.1|AYG84426.1|7395545_7396061_-|hypothetical-protein
MVDSEAWGDEVYQPDGSEVQDDEGLLGAEDTLDDGPPDPLDVGYSPPDRPWAVESTGVTAAERLRGDSLEQRLATEVPEAAAAEGDGIGDTWDTDGEPRDNEVGGARAGRLVAPDEGAHPDDETRLLATDVGIDGAAASAEEAAMHIVDEDDTADLDGFEDPAGTESGDTR
>CP032698.1|AYG84427.1|7396244_7397201_+|Epimerase-family-protein
MKIVIPGGTGQVGTVLDRALTAAGHEVAILTRSPRGEREVAWDGETLGPWADVVDGSDVVINLAGRSVSCRYTETNLRAMMDSRVRSARVVGEAIEAAARPPKVWLQMSTATVYAHRFDAANDEASGVVGGAEPDVPGYWGFSVEIAKAWEAAQEQARTPDTRKVALRSAMVMSPDRAGVFDVLLKLARLGLGGPVAGGAQYVSWIHDRDFVRAVEFLVERDDLTGPVNLAAPGPLPQRAFMRALRRARGVPVGLPARKWMAELGAFALRSDTELLLKSRRVVPGRLLDAGFTFEHPEWPGAAADLVRRVRTARRGAN
>CP032698.1|AYG84428.1|7397197_7397557_-|hypothetical-protein
MAISALAASKLALSPLWTGAAHQALRTATLVLLGLNLAGCAVLLVAEVGRPRPGYDIRRWSTVFPLGMTAVAALSTATATGVGPLRTLGEVVLWITVAAWLLTLAGFARRHAQLPGRIG
>CP032698.1|AYG84429.1|7397632_7398145_-|hypothetical-protein
MRREVERWWAELPPAAGAAVMATAIISIGLRLTGHEALSLAALIVAGALWLLLACDFVARLFTNRRRWSGEADTPAALTAVAATTVLGTRLSALGAHGPALALLALAAALWPGLLVAVVRHWRRPMPGAAFLVCVATQGLGVLAATLSLAGEGDRLGWAALVALGLGLVL

Crispr_ID: CP032698_96

• CRISPR_ID: CP032698_96
• CRISPR_location: 7573987-7574123
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_96

Consensus_repeat	Method
TTAGGGGCGCGGGGAACTGCGCGA	CRISPRCasFinder

spacers of CP032698_96

>96.1|7574011|33|CP032698|CRISPRCasFinder
CCAGCCCCGCACGGTCCGCAGACCGAAGGGCTT
>96.2|7574068|32|CP032698|CRISPRCasFinder
GAAGCGACCGCGGTCCGTAGGTTCGAGAGGGT

CRISPR arrays and Neighbor proteins around CP032698_96

CRISPR arrays

The CRISPR arrays of CP032698_96

>merge|CP032698|96|7573987-7574123|CRISPRCasFinder
TTAGGGGCGCGGGGAACTGCGCGACCAGCCCCGCACGGTCCGCAGACCGAAGGGCTTTTAGGGGCGCGAGGAACTGCGCGAGAAGCGACCGCGGTCCGTAGGTTCGAGAGGGTTTAGGGGCGCGGGGAACTGCGCGA

>CP032698|96|69|7573987-7574123|CRISPRCasFinder
TTAGGGGCGCGGGGAACTGCGCGA	CCAGCCCCGCACGGTCCGCAGACCGAAGGGCTT
TTAGGGGCGCGAGGAACTGCGCGA	GAAGCGACCGCGGTCCGTAGGTTCGAGAGGGT
TTAGGGGCGCGGGGAACTGCGCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG84582.1|7566465_7567365_-|Demethylmenaquinone-methyltransferase	unknown	unknown	gnl|CDD|369777
CP032698.1|AYG84597.1|7578378_7578753_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84593.1|7576038_7576518_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84589.1|7571741_7572056_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84581.1|7564679_7566227_-|putative-MFS-type-transporter-EfpA	unknown	unknown	gnl|CDD|129794
CP032698.1|AYG84594.1|7576514_7577081_-|hypothetical-protein	unknown	unknown	gnl|CDD|379228
CP032698.1|AYG84595.1|7577440_7577947_-|hypothetical-protein	unknown	unknown	gnl|CDD|367130
CP032698.1|AYG84583.1|7567523_7567751_-|hypothetical-protein	unknown	unknown	gnl|CDD|375043
CP032698.1|AYG84600.1|7581638_7582886_-|putative-nitrate/nitrite-transporter-NarK2	unknown	unknown	gnl|CDD|225133
CP032698.1|AYG84592.1|7575249_7575906_-|hypothetical-protein	unknown	unknown	gnl|CDD|371689
CP032698.1|AYG84591.1|7574341_7575193_+|Arylamine-N-acetyltransferase	unknown	unknown	gnl|CDD|366312
CP032698.1|AYG84596.1|7578139_7578379_+|Antitoxin-Phd	unknown	unknown	gnl|CDD|370460
CP032698.1|AYG84599.1|7579524_7581672_+|DNA-helicase-IV	unknown	unknown	gnl|CDD|226482
CP032698.1|AYG84598.1|7578793_7579426_+|Putative-mycofactocin-biosynthesis-transcriptional-regulator-MftR	unknown	unknown	gnl|CDD|188483
CP032698.1|AYG84587.1|7570197_7570767_+|hypothetical-protein	unknown	unknown	gnl|CDD|378427
CP032698.1|AYG84586.1|7569675_7570107_-|hypothetical-protein	unknown	unknown	gnl|CDD|378915
CP032698.1|AYG84590.1|7572159_7573509_-|Macrolide-export-protein-MacA	unknown	unknown	gnl|CDD|273776
CP032698.1|AYG84585.1|7568895_7569486_-|Putative-xanthine-dehydrogenase-YagT-iron-sulfur-binding-subunit	unknown	unknown	gnl|CDD|236910
CP032698.1|AYG84584.1|7567900_7568899_-|Putative-xanthine-dehydrogenase-YagS-FAD-binding-subunit	unknown	unknown	gnl|CDD|224238
CP032698.1|AYG84588.1|7570886_7571717_+|NH(3)-dependent-NAD(+)-synthetase	unknown	unknown	gnl|CDD|234831

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG84582.1|7566465_7567365_-|Demethylmenaquinone-methyltransferase	gnl|CDD|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	2.42007e-21
CP032698.1|AYG84599.1|7579524_7581672_+|DNA-helicase-IV	gnl|CDD|226482	COG3973, COG3973, Superfamily I DNA and RNA helicases [General function prediction only].	2.70284e-67
CP032698.1|AYG84581.1|7564679_7566227_-|putative-MFS-type-transporter-EfpA	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	5.85205e-61
CP032698.1|AYG84594.1|7576514_7577081_-|hypothetical-protein	gnl|CDD|379228	pfam13508, Acetyltransf_7, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	1.32395e-10
CP032698.1|AYG84595.1|7577440_7577947_-|hypothetical-protein	gnl|CDD|367130	pfam02627, CMD, Carboxymuconolactone decarboxylase family. Carboxymuconolactone decarboxylase (CMD) EC:4.1.1.44 is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway. In these bifunctional proteins CMD represents the C-terminal domain, pfam00561 represents the N-terminal domain.	8.65808e-11
CP032698.1|AYG84583.1|7567523_7567751_-|hypothetical-protein	gnl|CDD|375043	pfam17196, DUF5133, Protein of unknown function (DUF5133). This protein of unknown function is part of the Borrelidin synthesis genomic cluster. Borrelidin is a polyketide antibiotic.	3.84401e-22
CP032698.1|AYG84600.1|7581638_7582886_-|putative-nitrate/nitrite-transporter-NarK2	gnl|CDD|225133	COG2223, NarK, Nitrate/nitrite transporter [Inorganic ion transport and metabolism].	3.44335e-88
CP032698.1|AYG84592.1|7575249_7575906_-|hypothetical-protein	gnl|CDD|371689	pfam11716, MDMPI_N, Mycothiol maleylpyruvate isomerase N-terminal domain.	3.32587e-09
CP032698.1|AYG84591.1|7574341_7575193_+|Arylamine-N-acetyltransferase	gnl|CDD|366312	pfam00797, Acetyltransf_2, N-acetyltransferase. Arylamine N-acetyltransferase (NAT) is a cytosolic enzyme of approximately 30kDa. It facilitates the transfer of an acetyl group from Acetyl Coenzyme A on to a wide range of arylamine, N-hydroxyarylamines and hydrazines. Acetylation of these compounds generally results in inactivation. NAT is found in many species from Mycobacteria (M. tuberculosis, M. smegmatis etc) to man. It was the first enzyme to be observed to have polymorphic activity amongst human individuals. NAT is responsible for the inactivation of Isoniazid (a drug used to treat Tuberculosis) in humans. The NAT protein has also been shown to be involved in the breakdown of folic acid.	1.51074e-54
CP032698.1|AYG84596.1|7578139_7578379_+|Antitoxin-Phd	gnl|CDD|370460	pfam09386, ParD, Antitoxin ParD. ParD is a plasmid anti-toxin than forms a ribbon-helix-helix DNA binding structure. It stabilizes plasmids by inhibiting ParE toxicity in cells that express ParD and ParE. ParD forms a dimer and also regulates its own promoter (parDE).	0.000446185
CP032698.1|AYG84598.1|7578793_7579426_+|Putative-mycofactocin-biosynthesis-transcriptional-regulator-MftR	gnl|CDD|188483	TIGR03968, transcriptional_regulator_TetR_family, mycofactocin system transcriptional regulator. Members of this family are TetR family putative transcriptional regulators that occur in genome contexts near proteins of the mycofactocin system. These include the precursor peptide (TIGR03969), a radical SAM peptide maturase (TIGR03962), and a putative carrier protein (TIGR03967). [Regulatory functions, DNA interactions].	2.15319e-13
CP032698.1|AYG84587.1|7570197_7570767_+|hypothetical-protein	gnl|CDD|378427	pfam10400, Vir_act_alpha_C, Virulence activator alpha C-term. This structure is homo-dimeric, and the domain here is the C-terminal half of the structure, often associated with PadR upstream, (pfam03551), which is a transcriptional regulator.	2.07672e-15
CP032698.1|AYG84586.1|7569675_7570107_-|hypothetical-protein	gnl|CDD|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	6.1903e-05
CP032698.1|AYG84590.1|7572159_7573509_-|Macrolide-export-protein-MacA	gnl|CDD|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	4.28755e-24
CP032698.1|AYG84585.1|7568895_7569486_-|Putative-xanthine-dehydrogenase-YagT-iron-sulfur-binding-subunit	gnl|CDD|236910	PRK11433, PRK11433, aldehyde oxidoreductase 2Fe-2S subunit; Provisional.	2.3037e-50
CP032698.1|AYG84584.1|7567900_7568899_-|Putative-xanthine-dehydrogenase-YagS-FAD-binding-subunit	gnl|CDD|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	1.24737e-78
CP032698.1|AYG84588.1|7570886_7571717_+|NH(3)-dependent-NAD(+)-synthetase	gnl|CDD|234831	PRK00768, nadE, ammonia-dependent NAD(+) synthetase.	2.86872e-168

Protein sequences

>CP032698.1|AYG84590.1|7572159_7573509_-|Macrolide-export-protein-MacA
MKVLPRLHKAVLLNSALGAVLIAAVGGAYAVVATSDSDTPRRTATRTAAVSTGKVQATVAGAGLLASPSDAGVNFTTGGQLTRVEVKPGDKVTKGQLLAKVDDKTAREAVTQAKTALAAAKANLASVQAGQPASPPATPNTNPSGKSSAPASPTPKPTPTPPVSPTPTPSATTTPTPTPKSLTGAAAEQSTDEGSAIRMEPVAHTAVDPNLLIQAQAQVAQAQSTLDAAQRALEGTVLTAPVDGTVASVGATVGQTVIGTTYASGAGTPPGAPAPAASNAPAPGGSSAAPSGFIVLTNPTGMQVKANVSEADALRLKPGQAATVTLTAQSTTTLNAKVLSVGTLAVNGPAGSGAAGQYLVTLDIMGPTTDLHTGQGVSVQIVAGEASDALFVPTAALIGSGAKRTVTVVAADGTAHSAQVTVGVESDTNTQITSGLTQGQKVRITTVAP
>CP032698.1|AYG84589.1|7571741_7572056_-|hypothetical-protein
MVRDRDAFTKTDGQDPDPATVAAPALNTAPSAPREQGAATASPVVDTAVRPTPPSGAHVPGATPAERRTVPWRQLPWLTLLLAVGIVAALAFIAGVLVEQHHLQ
>CP032698.1|AYG84588.1|7570886_7571717_+|NH(3)-dependent-NAD(+)-synthetase
MSEPASIALQQEIARELEVAETFEAEREIERRVAFLAERLTSTGLRCLVLGISGGVDSTTAGRLCQLAVERARAAGHEARFYAMRLPYGVQADEHDAQLALSFIQPDHVLTVDIKPASDAALQACVAADVAFRDEAHQDFVQGNIKARQRMIAQYAVAGAHQGLVVGTDHAAEAVSGFFTKFGDGAADLVPLTGLTKRRVRAVADALGAPSELVWKVPTADLETLAPGKADEDALGVTYDDIDDFLEGKPVDGRAVETIVNRYRLTEHKRRLPIAP
>CP032698.1|AYG84587.1|7570197_7570767_+|hypothetical-protein
MALRHAVLAALLDGEFSGYQLAKAFDIGVANFWHALPQQLYAELAKLEKDGLVAGRQVVQETRPNKRLFHVTDAGRAELETFAAATAKPSFIRDDLLVKVQAADRIGTAPVIGQLEERAAAADAKIELLGALLRQLRGDRDEDDFLLHGERIGPYLTCLRGLAFEREHRDWCRRIAAVLRERHRADAER
>CP032698.1|AYG84586.1|7569675_7570107_-|hypothetical-protein
METAERFRAAVEKRDVSALEGLFTEDVRLYSPVKFVPFEGRAMVLGLFGVLVRVFEDLRYLGRLDGAAETSADGEEAPSVVLPFRATVAGKQIHGIDLLQFDEAGLIKEFTVMVRPQSAVHALGQAVLAGLVADDLAPAPAEG
>CP032698.1|AYG84585.1|7568895_7569486_-|Putative-xanthine-dehydrogenase-YagT-iron-sulfur-binding-subunit
MEARHGRQERRPGLVTRVFGHGVTDSHVTLRVNDAEHRVELEHCATLLEVLRENLGLTASRKGCDDGRCGECTVLLDGRRVNSCLLLAVAQEGREIVTVEGLVAADADDDRHPLRRAVVDRDVVQCAYCAPDQHRSAAAGSAGAPSGPSSVVTDIDLPPDAPVRLTAAEVRDRLSGNLCRCGAYPSGAEAVQDVIV
>CP032698.1|AYG84584.1|7567900_7568899_-|Putative-xanthine-dehydrogenase-YagS-FAD-binding-subunit
MKPVAYVRPRNLAEAAAAHGGRPEARYLGGGTNLVDLMRLGVERPDLLVDITRLPLDAIEEQPDGSVRVGATVRNSDLATHPALRDRYPVLPQALLSGASGQLRNMATTAGNLLQRTRCGYFQDLSRPCNKRVPGSGCGAIEGVNREHAVFGHSSLCVATHPSDLAVALAALDALVELEGPGGTRAVPVTEFYRLPQDRPEVDTVMRPGEIVTAVVVPSAPEGSVSRYRKARDRAGHTFALASVAALVHLERGVVREVALAFGGLAHRPWRARRTEAALLGTAPTAETIERAVDAELADAVPLRHNAYKVELARGLAREVLESLAQVRPAGR
>CP032698.1|AYG84583.1|7567523_7567751_-|hypothetical-protein
MLMAHPAVLRDLLDEYEALLVLNAAEGDEATRQRLDDVTYTLCVSTGTRDIDAAVIAARHRLPGARTFDDSVLTA
>CP032698.1|AYG84582.1|7566465_7567365_-|Demethylmenaquinone-methyltransferase
MHAMGEGSEPTASPAPFTSKRRGRSRPGPGEPTDFDAVQRLMWAGRAQAYASSFAGVCAHPVPQLLDAARVGAGVRVLDVGTGTGTVAEAACARGAGVTGVDAEVDMVDWAARAVPQAAIQLAVLPQLPFADGFFDAVTANFVLDHVGRPGAAIAELRRVVRPGGRIAVTLWAVPEAAGQSLLGRAVRAAGVTLPSGLSAPAAEDDFPRTVPGLAGLLTSSGLRDVTCEPVHWEHRVPADTWWAGAAAGLGTVGQVVASRPERIRAEIRRHFDLLSAEFTIGRGELALPHSALLACGHR
>CP032698.1|AYG84581.1|7564679_7566227_-|putative-MFS-type-transporter-EfpA
MTSSQPAPKVETAPPSGGGGGNGIALLVIAACQLMVVLDITIVNIALPHIQSALHFSTTSLAWVVSAYTLTFGGLLLLGGRAGDILGRRRVFMCGVLLFALASLFGGLSQNAGQLLAARAVQGVGGAIASPTALALITTTFTEGPARNRAFGVFAAVSAGGSAIGLLAGGVLVEWLDWRWVLFVNVPIAVLILLATPRHIKESERHAGHFDIAGATTSTLGMVALVYGFIRAAQEGWRDPFTLGSFAAAVVLLSAFVLVERRSQQPITPLHMFADRNRAGTYGMMLSLSAAIFGMFFFLTLFVQDVLGFSALQAGLAFLPVSAIIAVGAGLTSQLLPKYGPKPFMVTGAILAAGGLSWLTQTDIHSTYPGSILGPLLVFGLGMGLNFVSLTLMAVSGVPPHEAGAASGMLNVTQQVGGSLGLSILVTVFGTAGRNEARDQIPKFLGQADPAQRLMFRRTGQLPRPWSDQVLTSGVSMAFVVAAIFAVIAALIAVLAIQVRPSDLERLQGAGPPHS
>CP032698.1|AYG84591.1|7574341_7575193_+|Arylamine-N-acetyltransferase
MWNGDALDLDAYLAHLGHRGDRTPTLATLRALHRAHVLSVRWENVEAVLRKYRPLDLESVQAKMVGNARGGTCFEHVTLYAAALERLGFEFFVVQGRVSMGSPTIRPETHAMAIVELEGRRWLSDVGFGASPLEPIELTDATDVTDAVWPYRLRRQEVTPGETGWALYQPADQREGTEQTADGWMVRHTFTLHRQYPVDLKVSNHYGASSPHSPFSDRLCLQRVHPDRLHLLDNRRLTTIRPGVAGFPETRELEPNEVPKVLADVFGVELSTRDVDLLLAKLA
>CP032698.1|AYG84592.1|7575249_7575906_-|hypothetical-protein
MDLFVRSWAALRAAVAGLADRDFEHPSGCAGWLMRDLVCHLVIDAQDVLITLVTPAETEPTVDAVTYWHVGNEPPAGDDPLDALTVRLAAAYEQPGLLAFHLDDVGSAAGRAAELADPDARVRTQGQVLTARDYLTAYVLEWTLHHLDLSGPLPHVPGPPAEGLARSRTLLEAIAEAEFPASFTDTDALLIGTGRRAPTPGETAELGTLAARLPLVLG
>CP032698.1|AYG84593.1|7576038_7576518_-|hypothetical-protein
MMDDWRTDRIASALRGENPTVLRRLRAGFAVIGDVQFLPGYSVLLVDDPRVQRLSEMAKPKRRDFLADLDVLGEAVEHACRRLDPAFRRVNLEILGNTDGFLHAHVWPRFDWEPAELVRVPVWLYPHENWSDPRHALSPRHDALRAAITAQLDRLSALD
>CP032698.1|AYG84594.1|7576514_7577081_-|hypothetical-protein
MGRDARWVLRRAEPADVERIVEIRAVVMRPDLERLGRFDAHRVRQRFRDAFSPAHTSVVVADGAVAGCVALRAAEDGYWLEHFYLAPALQGRGVGSAVLRTVLGRADADGMPVRLNVLRGSAAQRLYERHGFTLQAQDPVDVFMVREPSVEPHRAPGPTVPASASASASASASASASASASVSRRLPA
>CP032698.1|AYG84595.1|7577440_7577947_-|hypothetical-protein
MQTRSITTRVPMGPRMSEDPGQLVPELAEVSAALFRVTGNGSVPRSTISLVQLRAGQIVGSTYLTVLHTGFLRKAGESEERITSVVSWQDSPYFTEAERAALALVEAVLQPAAQGERVPDELYALAAEHYEPKALATLMFAIGQVNFFLAVALIAKPVPGRAFSDPWN
>CP032698.1|AYG84596.1|7578139_7578379_+|Antitoxin-Phd
MPSLNITFTDEELEAVRAAAAADGKSLKQYVHDLPLREQQRLQFVRYALSWGEHQRAEFDEAFPDEAPPSARNEGVDAA
>CP032698.1|AYG84597.1|7578378_7578753_+|hypothetical-protein
MVLYIDVPWLLDVQEQAVPEDVSVADYSALVAAVARHKTRIPRPATADPEPSWRAAALLHTLVRLQPLPHRNSLYACQVTAAYMYASGEGIDPPYGAMVDLVRDIQAGKVSVYQAADRIRAWRI
>CP032698.1|AYG84598.1|7578793_7579426_+|Putative-mycofactocin-biosynthesis-transcriptional-regulator-MftR
MSSEMGLRERKRRQTFAAVSEAAIGLFLERGFDKVSVAEVAAAAGISKPTLFRYFPTKEDLVLHRFADHEDEAARVVAAGRAAGVAPLPALRARFREGLERRDPVTGLCDDPRVRAYHALLYGTPSLVARLHGYQGRSEEALAAELGEGVGARVAAGQIIAVQRILAEENWNRIARGESARALYEEAVAAADQAFGQLARGLGREYGEVA
>CP032698.1|AYG84599.1|7579524_7581672_+|DNA-helicase-IV
MTSLDRELGKELDPKPGRELGRELGPKPDRELGPKPDRELARQLAQERAHHDACRAALAAMTEGADERVVNGENAFASGADAEVLGYQLRSWAKELRDMPQGPLFFGRLDFDACADADHAGQSYHIGRRRISEHPFAPPLVVDWRAPVSRRFYQASARDPQGVEVRRRFGWARGSLGAAEDLTGLEDERLTAGEAHRTSAILAGEIERPRVGPMRDIAATIQPEQDDLVRSELARSICVQGAPGTGKTAVGLHRAAYLLYTHPQRLQRRGLLVLGPNRTFLSYVCEVLPALGESGIRQSTVDEEVARGTRGREVRAVDAPETARVKHDARMAEVLRRALYGRVAHPVNSLALREGSMTWRVSRDELASIVASVRAEAPPYAIGRERVRSRAVRAIQLQAERRAGPMNNTWLQKITRARPVTEYVDTVWPRVKPEEVLADLLTDPEALASAAEGVLDGAEQQALLWAGPPRSWKSARWSAADLILLDEVSGLIEHPEGYGHIVVDEAQDLSPMQCRAIARRAVFGSLTVLGDLAQGTTPWAARDWRRQLAHLGKPDAVVVPLTTGFRVPAAIVELANRLLPALDVDVPPGRSLRGDGRLSHRLAATPEGLAAEVVEAVRAALRGEGSVGVIAADHEVPALRAALAAAGFDASGAARVALLPATLAKGLEYDHVVAVEPAEIAASEERGLHRLYVVLTRAVSGLDIVHSRPLPSELA
>CP032698.1|AYG84600.1|7581638_7582886_-|putative-nitrate/nitrite-transporter-NarK2
MDTDSKPSGAAYRNLVMATVGFTLTFWAWDLIAPLAGDYKDRLHLSSLQQSLLVAVPVLVGSLGRIPVGALTDRYGAKLMFPLMSALTIVPVLLLIPARDSYGLMLVIGFLLGLGGTTFAIGIPLVNSWFPPHKRGLALGVFGMGMGGVALSGYLTPRIAKHGYHVPFLVVAIALAVYAVLAALLITDRPDRPVPTATLGSRLGRAGRLRVTWELSALYAIGFGGIVAFGVYLPTYLKTWYALSPTDAGSKAAGFALATVLFRPIGGWLSDRVHPALVTAGALLAVALLAIVQAFDPPLYPGGTTALLCMGAGLGTASGSVFALVSQVTPQPQVGSVTGIVGAMGGLGGFVPPLVMGAIYSAKDSYSIGFMLLSDLALAGCVYAFARMRTSRPPSEAPPVKSPQTQASSEGSGLL

Crispr_ID: CP032698_97

• CRISPR_ID: CP032698_97
• CRISPR_location: 7776803-7776909
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of CP032698_97

Consensus_repeat	Method
CGCCCGCCCCGCCGCGCCCCCCCG	CRISPRCasFinder

spacers of CP032698_97

>97.1|7776827|17|CP032698|CRISPRCasFinder
GCCAAGCCCCGCCCGCC
>97.2|7776868|18|CP032698|CRISPRCasFinder
TGCCCCCGCCCGGCCGTG

CRISPR arrays and Neighbor proteins around CP032698_97

CRISPR arrays

The CRISPR arrays of CP032698_97

>merge|CP032698|97|7776803-7776909|CRISPRCasFinder
CGCGCGCCCCGCCAAGCCCCGCCCGCCAAGCCCCGCCCGCCCCGCCGCGCCCCCCCGCCCCGCCGTGCCCCCGCCCGGCCGTGCGCCCGCCCCGCCGAGCCCCCCCG

>CP032698|97|70|7776803-7776909|CRISPRCasFinder
CGCGCGCCCCGCCAAGCCCCGCCC	GCCAAGCCCCGCCCGCC
CCGCCGCGCCCCCCCGCCCCGCCG	TGCCCCCGCCCGGCCGTG
CGCCCGCCCCGCCGAGCCCCCCCG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG84755.1|7776083_7776398_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84764.1|7784422_7785274_-|Alginate-lyase	unknown	unknown	gnl|CDD|378049
CP032698.1|AYG84750.1|7771762_7773085_-|Aldehyde-dehydrogenase	unknown	unknown	gnl|CDD|143406
CP032698.1|AYG84757.1|7777123_7777480_+|hypothetical-protein	unknown	unknown	gnl|CDD|319911
CP032698.1|AYG84759.1|7780262_7780442_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84754.1|7775764_7776013_+|hypothetical-protein	unknown	unknown	gnl|CDD|375043
CP032698.1|AYG84752.1|7774249_7775113_+|HTH-type-transcriptional-regulator-BenM	unknown	unknown	gnl|CDD|223656
CP032698.1|AYG84747.1|7767535_7768492_-|Rhamnolipids-biosynthesis-3-oxoacyl-[acyl-carrier-protein]-reductase	unknown	unknown	gnl|CDD|235737
CP032698.1|AYG84751.1|7773245_7774181_-|Threonine/homoserine-exporter-RhtA	unknown	unknown	gnl|CDD|227339
CP032698.1|AYG84761.1|7782083_7782488_-|hypothetical-protein	unknown	unknown	gnl|CDD|379209
CP032698.1|AYG84760.1|7780693_7782061_+|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl|CDD|365903
CP032698.1|AYG84765.1|7785613_7786168_+|hypothetical-protein	unknown	unknown	gnl|CDD|377417
CP032698.1|AYG84762.1|7782575_7783688_-|Virginiamycin-B-lyase	unknown	unknown	gnl|CDD|369882
CP032698.1|AYG84749.1|7770691_7771606_+|hypothetical-protein	unknown	unknown	gnl|CDD|270704
CP032698.1|AYG84753.1|7775153_7775504_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84766.1|7786419_7786734_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG84748.1|7768941_7770393_-|Proline/betaine-transporter	unknown	unknown	gnl|CDD|340924
CP032698.1|AYG84758.1|7777722_7780125_+|UvrABC-system-protein-A	unknown	unknown	gnl|CDD|223256
CP032698.1|AYG84756.1|7776540_7776735_+|hypothetical-protein	unknown	unknown	gnl|CDD|283241
CP032698.1|AYG84763.1|7783824_7784094_-|hypothetical-protein	unknown	unknown	gnl|CDD|182475

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG84765.1|7785613_7786168_+|hypothetical-protein	gnl|CDD|377417	pfam04892, VanZ, VanZ like family. This family contains several examples of the VanZ protein, but also contains examples of phosphotransbutyrylases.	9.70465e-29
CP032698.1|AYG84764.1|7784422_7785274_-|Alginate-lyase	gnl|CDD|378049	pfam08787, Alginate_lyase2, Alginate lyase. Alginate lyases are enzymes that degrade the linear polysaccharide alignate. They cleave the glycosidic linkage of alignate through a beta-elimination reaction. This family forms an all beta fold and is different to all alpha fold of pfam05426.	1.40631e-73
CP032698.1|AYG84750.1|7771762_7773085_-|Aldehyde-dehydrogenase	gnl|CDD|143406	cd07087, ALDH_F3-13-14_CALDH-like, ALDH subfamily: Coniferyl aldehyde dehydrogenase, ALDH families 3, 13, and 14, and other related proteins. ALDH subfamily which includes NAD(P)+-dependent, aldehyde dehydrogenase, family 3 member A1 and B1 (ALDH3A1, ALDH3B1, EC=1.2.1.5) and fatty aldehyde dehydrogenase, family 3 member A2 (ALDH3A2, EC=1.2.1.3), and also plant ALDH family members ALDH3F1, ALDH3H1, and ALDH3I1, fungal ALDH14 (YMR110C) and the protozoan family 13 member (ALDH13), as well as coniferyl aldehyde dehydrogenases (CALDH, EC=1.2.1.68), and other similar sequences, such as the Pseudomonas putida benzaldehyde dehydrogenase I that is involved in the metabolism of mandelate.	0
CP032698.1|AYG84757.1|7777123_7777480_+|hypothetical-protein	gnl|CDD|319911	cd07247, SgaA_N_like, N-terminal domain of Streptomyces griseus SgaA and similar domains. SgaA suppresses the growth disturbances caused by high osmolarity and a high concentration of A-factor, a microbial hormone, during the early growth phase in Streptomyces griseus. A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) controls morphological differentiation and secondary metabolism in Streptomyces griseus. It is a chemical signaling molecule that at a very low concentration acts as a switch for yellow pigment production, aerial mycelium formation, streptomycin production, and streptomycin resistance. The structure and amino acid sequence of SgaA are closely related to a group of antibiotics resistance proteins, including bleomycin resistance protein, mitomycin resistance protein, and fosfomycin resistance proteins. SgaA might also function as a streptomycin resistance protein.	1.01651e-15
CP032698.1|AYG84754.1|7775764_7776013_+|hypothetical-protein	gnl|CDD|375043	pfam17196, DUF5133, Protein of unknown function (DUF5133). This protein of unknown function is part of the Borrelidin synthesis genomic cluster. Borrelidin is a polyketide antibiotic.	7.19565e-07
CP032698.1|AYG84752.1|7774249_7775113_+|HTH-type-transcriptional-regulator-BenM	gnl|CDD|223656	COG0583, LysR, Transcriptional regulator [Transcription].	5.57663e-31
CP032698.1|AYG84747.1|7767535_7768492_-|Rhamnolipids-biosynthesis-3-oxoacyl-[acyl-carrier-protein]-reductase	gnl|CDD|235737	PRK06197, PRK06197, short chain dehydrogenase; Provisional.	1.67275e-71
CP032698.1|AYG84758.1|7777722_7780125_+|UvrABC-system-protein-A	gnl|CDD|223256	COG0178, UvrA, Excinuclease ATPase subunit [DNA replication, recombination, and repair].	0
CP032698.1|AYG84761.1|7782083_7782488_-|hypothetical-protein	gnl|CDD|379209	pfam13474, SnoaL_3, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	0.00738388
CP032698.1|AYG84760.1|7780693_7782061_+|D-alanyl-D-alanine-carboxypeptidase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	6.44129e-50
CP032698.1|AYG84762.1|7782575_7783688_-|Virginiamycin-B-lyase	gnl|CDD|369882	pfam08450, SGL, SMP-30/Gluconolaconase/LRE-like region. This family describes a region that is found in proteins expressed by a variety of eukaryotic and prokaryotic species. These proteins include various enzymes, such as senescence marker protein 30 (SMP-30), gluconolactonase and luciferin-regenerating enzyme (LRE). SMP-30 is known to hydrolyze diisopropyl phosphorofluoridate in the liver, and has been noted as having sequence similarity, in the region described in this family, with PON1 and LRE.	5.78357e-15
CP032698.1|AYG84749.1|7770691_7771606_+|hypothetical-protein	gnl|CDD|270704	cd05155, APH_ChoK_like_1, Uncharacterized bacterial proteins with similarity to Aminoglycoside 3'-phosphotransferase and Choline kinase. This subfamily is composed of uncharacterized bacterial proteins with similarity to APH and ChoK. Other APH/ChoK-like proteins include ethanolamine kinase (ETNK), macrolide 2'-phosphotransferase (MPH2'), an unusual homoserine kinase, and uncharacterized proteins with similarity to the N-terminal domain of acyl-CoA dehydrogenase 10 (ACAD10). These proteins catalyze the transfer of the gamma-phosphoryl group from ATP (or CTP) to small molecule substrates, such as aminoglycosides, macrolides, choline, ethanolamine, and homoserine. Phosphorylation of the antibiotics, aminoglycosides, and macrolides leads to their inactivation and to bacterial antibiotic resistance. Phosphorylation of choline, ethanolamine, and homoserine serves as precursors to the synthesis of important biological compounds, such as the major phospholipids, phosphatidylcholine and phosphatidylethanolamine and the amino acids, threonine, methionine, and isoleucine. The APH/ChoK-like subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and phosphoinositide 3-kinase (PI3K).	4.77567e-97
CP032698.1|AYG84748.1|7768941_7770393_-|Proline/betaine-transporter	gnl|CDD|340924	cd17366, MFS_ProP, Proline/betaine transporter of the Major Facilitator Superfamily of transporters. This subfamily is composed of Escherichia coli proline/betaine transporter, also called proline porter II (PPII), and similar proteins. ProP is a proton symporter that senses osmotic shifts and responds by importing osmolytes such as proline, glycine betaine, stachydrine, pipecolic acid, ectoine and taurine. It is both an osmosensor and an osmoregulator which is available to participate early in the bacterial osmoregulatory response. The ProP subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	0
CP032698.1|AYG84751.1|7773245_7774181_-|Threonine/homoserine-exporter-RhtA	gnl|CDD|227339	COG5006, rhtA, Threonine/homoserine efflux transporter [Amino acid transport and metabolism].	5.63657e-67
CP032698.1|AYG84756.1|7776540_7776735_+|hypothetical-protein	gnl|CDD|283241	pfam05532, CsbD, CsbD-like. CsbD is a bacterial general stress response protein. It's expression is mediated by sigma-B, an alternative sigma factor. The role of CsbD in stress response is unclear.	4.6503e-05
CP032698.1|AYG84763.1|7783824_7784094_-|hypothetical-protein	gnl|CDD|182475	PRK10457, PRK10457, hypothetical protein; Provisional.	5.96398e-13

Protein sequences

>CP032698.1|AYG84756.1|7776540_7776735_+|hypothetical-protein
MGDSAMDKIKGKAKEAAGKVTGNDRMAAEGKTDQAKGKTKDAMDTMKKRAQGTRDSLTEERDDI
>CP032698.1|AYG84755.1|7776083_7776398_-|hypothetical-protein
MSLPDAITATLAARDKVDFEQDFARTRQIMTFVHATDDAEAVELAMFEGPLPIPVVGQTVTLWITGHPLVVQRVETHYGLGGADTHPKREQVASVIVFVAPRTA
>CP032698.1|AYG84754.1|7775764_7776013_+|hypothetical-protein
MLSPHWYVVHELLSLLRSRERRAARSPLDSGARQARDDAAYTLCVLMGERSVAAAVEAAERHLARCRRAAPPGVATAPHRTR
>CP032698.1|AYG84753.1|7775153_7775504_-|hypothetical-protein
MSDDIWDYHPTAGYRAGVELVGYRVEATDGHIGKIDEHSETVGAAYLVVDTGVWIFGKRVLLPVGTITRIDTAERTVRVGRTKEEIRDAPEYDPAEHAGEPSYLERFARYYGQPRM
>CP032698.1|AYG84752.1|7774249_7775113_+|HTH-type-transcriptional-regulator-BenM
MTIELRHLRAFLAIADEGNVTRAAARLHLSQPALSRTLRQLEDHLGVRLVDRSTHHLGLTREGHTFRDKAAAALAAVDTALDPGGTRGWPLRLGHTWAALGDHTVALLRRWDETWPGTPLELLRIDDRTAGLSQGKVDAALLRGAVTCAGLRTELLVTERRVVVMAADSPLVALPDVTLADLAAHPIALNTVSGTTSMELWPSGARPVTTLEVSNTDEWLIAVAAGRAVGVSTSATPSNYAHPSLVYRPLVDAPPVPVVLAWREGPGHPSVPDLLALARQVLAAGDA
>CP032698.1|AYG84751.1|7773245_7774181_-|Threonine/homoserine-exporter-RhtA
MTSTALDSPTFTTPTTTTPPTTSAPGFPRHSAGRGTLAGVGLVLAGTVSVQFGSAFAALLFPRAGALGTVALRVAFAAVLLLAVARPRLRGHTRADWAVACGFGLALGGMNILFYQAIDRIPLGAAVTFEVLGPLLLSVIVSRRAAGLLWAALALAGVYLLGRGDFDRLSVAGVAFALGAAAMWVAYILLNSRTGARFPRLDGLAIAMAVAALVSLPLGIGSAGGTLLEPGVLGLGLVIAIVSSGVPYTLELLALRRLPAATFAVLTALAPALAALAGYLVLHQGLSATQCAAIAMVVAASVGAVRSGGGR
>CP032698.1|AYG84750.1|7771762_7773085_-|Aldehyde-dehydrogenase
MNDHTPEQPAEIVARLRATFRSGHTQPVEWRTNQLRRLREMLTTHGADLAEALHADLGKSSTEAFRTEIDFTVREIDHTLDHLAEWLRPEPAPVPAHLGADATAHTQYDPLGVVLVIAPWNYPVQLLLTPMLGALAAGNAVVVKPSELAPATSAALARLLPRYLDTAAVAVVEGAVPETTALLAERFDHIFYTGNGTVGRIVMRAAAEHLTPVTLELGGKSPAFVDRGADLSVVADRLVRGKFLNAGQTCVAPDYVLTDPETARALEPEFVRAVERLFGAEPREAAEFGRIVNERHFDRLSALLDSGRTVTGGATDRATKYIAPTVLADVDPTSPVMREEIFGPILPVVTVADLDEAIAFINDRDKPLALYAFTESDATRARLAAETSSGGLGFGLPLAHLTVSDLPFGGVGESGMGNYHGRYSIETFSHRKAVLEKPLG
>CP032698.1|AYG84749.1|7770691_7771606_+|hypothetical-protein
MSATRMHPDEHPMSDALVRRLIAGQFPRWAGRAVERFASGGTVNAMYRLGDDLVVRLPLVAGGAGDVLREQEWLPRLVPLLPTAIPEVLGFGQPAEGYPWPWSVYRWRGGENPEAGAVREPVALAEDLAGFVTAMWSVTLPGAPTAHRGGPLDSLDEETRQAIRLLRGIPQEGIDCDAAETVWQDALREPDWDGPPVWLHADLMPGNLLVEGDRLTAVIDFGCAGVGDPACDLFPAWNLLPADGRQAFREALGVDDAMWRRGRARTLSQALIALPYYRNTNPAMARNARHVIAEVLRERDRVAN
>CP032698.1|AYG84748.1|7768941_7770393_-|Proline/betaine-transporter
MLSTEDHQPEAVTRHRSLFRAIHRRRNPALRRSDITVTDEAAVKRAVKATALGNAMEWFDFGVYSYLAVIIGKVFFSGAGDTMQVIASLATFAAAFLVRPLGGMFFGPLGDRVGRKKILALTMIMMAAATLAIGLIPSYATIGIWAPVLLILCRMVQGFSTGGEYGGAATFIAEYAPDKRRGFWGSFLEFGTLIGYTVAASLVTALTVLLSDDAMQQWGWRIPFLVAGPLGIVGLYLRLKLDESPAFKKLEEAGPSAVEHEKLPLKRILFGNGRAMVLCLALVAAFNICDYMLLSYMPTYLSTLGFDETGGLMSIVAVMIVLMALINSVGRLSDRVGRRPVLIGGSLGFIVLAVPCFLLIKQGGTAAVFIGLLVLGLALVCYMGTMSSALPALFPTAIRYGSLSIGFNISVSLFGGTTPLVVQGLIGATGNDLMPAFYTMLAGLVGLVAAIAMKETARKPLEGSPPSVATDEEAAELVAAQRA
>CP032698.1|AYG84747.1|7767535_7768492_-|Rhamnolipids-biosynthesis-3-oxoacyl-[acyl-carrier-protein]-reductase
MSSASQNRSWDVHRLPSARGKVFLVTGGNAGIGYFVAEQLAATGAVVVLGSRDAAKAGAAMASIRSRVAGAHLRHLPLDLADLSSLKGAADRLDLGHLDAVVHNAGVAFDDPPRRETKDGHELMFATNHLGHFALTQHLAPLLSAAPAARVVTVGSFAARSERLDLGDLQSREDYRPKRTYGRSKVAQMSFGFALDRHLRALHSTVLSVVAHPGGALDSLTPSRPPIHVTTPGERLRGLPAGLLVQGKDAGAWPIVRAVLDPEVRGGQLWGPKVFGLRGAPRLEPVPAHMADPVVAAALWAASGELTGTDPHLGFARP
>CP032698.1|AYG84757.1|7777123_7777480_+|hypothetical-protein
MTNASSTQGIKTVLHPVSDLAAAKAVYTALLGVAPTTDEPYYVGYEAEGQQIGLVPNGAEQGMASPVAHWHVPDIEAKLAEVIAAGAKVKEPTRDVGGGRLVATFTDPDGNVLGLIQG
>CP032698.1|AYG84758.1|7777722_7780125_+|UvrABC-system-protein-A
MENAISMAKRTDTRTPAPHAADSHDMIRVHGARVNNLKDVSIEIPKRRLTVFTGVSGSGKSSLVFNTVAAESQRLINETYSAFVQGFMPTLARPEVDVLDGLTTVITVDQQRMGGDPRSTVGTATDVNAMLRILFSRLGKPHIGSPKAFSFNVASISGAGAVTVRRGGQEVKERRSFSITGGMCPRCEGRGSVTDIDLTQLYDAGKSLNEGAFMIPGYTGGGWNSRLYIESGFFDPDKPIAKFTKKELQDLLHREPTRMKIAGINMTYEGLIPRVQKSMLSKDTDSMQPHIRAFVERAVTFTTCPDCDGTRLNEGARSSKIKRKNIADLCAMEIRDLAEWVRALKEPSVAPLLATLLETLDSFVEIGLGYLSLDRPSGTLSGGEAQRVKMIRHLGSSLTDVTYVFDEPTIGLHPHDIQRMNDLLLRLRDKGNTVLVVEHKPETIVIADHVVDLGPGAGTGGGTVCFEGTVEGLRTSGTITGRHFDDRAAVKNEVRRPNGTLEIRGASAHNLRNVDVDIPLGVLTVVTGVAGAGKSSLVHGSIPAGEGVVSVDQSPIRGSRRSNPATYTGLLDPIRKAFAKANGVKPALFSPNSEGACPTCNGAGVIYTDLAMMAGVATTCEECDGKRFEASVLDYHFAGRDISEVLALSVAEATEFFGTGEGATPAAHRILTRLTDVGLGYLSLGQPLTTLSGGERQRLKLATHMGEKGGVYVLDEPTAGLHLADVEQLLGLLDRLVDSGKSVIVVEHHQAVMAHADWIIDLGPGAGHDGGTVVFEGTPAQLAAARSTLTGEHLAKYVGA
>CP032698.1|AYG84759.1|7780262_7780442_-|hypothetical-protein
MSVIGRFPAGGPRGSWPAEELAAQLRRRGRQATVVMDLESDAFLVIERRHEEAAYSRAA
>CP032698.1|AYG84760.1|7780693_7782061_+|D-alanyl-D-alanine-carboxypeptidase
MRTKLARSAATLATALVLVAGNAAGAVAGNPESTGDMGTTGHAVNAFRPSGDDARSDPAPSLPEVRAALIRVMDAGAPGAFAVIRDHLHPERNGSLAVGEADLDGTPMWADARFRVGSNTKMFTSVLALRLAEQGRLDLDKPLRDYLPSGTIPASWPITARQVLEHRAGVYDHVNDLLEQSGEETTAAFEARIRDTVYDPRALVSLSVKHGLQFPPGSAYAYTNTGFVLMGLVAEHLSGRPYAELLREQILAPLGLRRTSFTVPEKRIVGPHASGYLTHDNPREPLLDATEQTGSWIWSAGGIVSSARDLDRFLTALLAGSAGGLISDDSLRQMTRSLPTGVPRIAYGLGLRQIALSCGVVLGHGGIVQGYQSQAFATQDGHRTVVVFANASNNGAVTQGLMDALEPAFCGPVQASAPRHSSSATHAPSVENQASNRASNRASVPAVPAVEDARM
>CP032698.1|AYG84761.1|7782083_7782488_-|hypothetical-protein
MTDAEAEIDQLMRAFLGAFTNTDGARPDLDVVRGVFIPQGMIINNSGTEPVVYGLDAFIAPREKILTDGTLTEFSEWEVHARTEVHGSIAHRLSEYAKSGIRDGLRFEGVGRKSTQFIRTPAGWRMSAMTWDDE
>CP032698.1|AYG84762.1|7782575_7783688_-|Virginiamycin-B-lyase
MTSPTPEHPGKSAELPAPCPLLTHNLRSRKIEDSGAGNECAQHPGQGRELMRPSNTPRTAIRGPRRSILFAAALAAAAALLTPATAHAAPACEANALGEPVQVARVPDWAESIVVDQRGRMFATAYFSGRVYRIDAPGSTPVALTGNVGANGGIVVRPDGQLLVGTGNDLGHSLTGDLLPVSKLLLVDPDSGRVSTYASGLGGIDGVALAPDGTVYTTTVGGRHIGRVTPDGRVDPAWAQLPMPNGIAVSPDGGQVYVIQTTPAPTLYRIPADDPAHPGRWISTSLPDTLALPDGLTLDSQGRPLIATHAAGQIWRAEAGALCSVQSGLYLSTQITYGHGDRGFSAGKLYRSGVDGKIYEIPAGADPAGH
>CP032698.1|AYG84763.1|7783824_7784094_-|hypothetical-protein
MGIIAWILIGLLAGAIAKALMPGKDPGGCFITMIIGIVGGLLGGWLGKVIFHVHSINGFFHLSTWIAAIIGSVIVLIIYRLLIGNRSRH
>CP032698.1|AYG84764.1|7784422_7785274_-|Alginate-lyase
MRIRPLLIPLATAAAAVGGLAFASPAPASPSTAPAFTGVVAESGNGLDAAGPAAAKAAVAPGGTFDLSVWELQEPVGSPGSPTTIPSSRLQGANGFQDAYFYTDSRDGAMTFWAPEKGVTTPNSHYARSELREMNRDGSPANWSLSGTHQLNATLRVVSVTSNVCVGQIHLGTGGSSTKPLLELYYRANGDIVLGTEDSPSGGQTSHTVGHVPVGKTWSYTIGVSGGHTIDLTVNGSTTHYPIPSSFNSYRQYFKAGSYNQSSSSSMTKGARVAFYKLTVAHG
>CP032698.1|AYG84765.1|7785613_7786168_+|hypothetical-protein
MVAFAVVLARATLVPSPMSVRLTHTNLHPGDSIRAYLAQPNWRDAVKQVGGNVVLGMPFGVLLPVLFPRTRGLVRVVLMTAFVMLMVEGAQGLLVTGRAFDIDDVILNSTGAFAGYLLLGRRLGRALHPRREHWWHRRPDEPTEAGKGKPAETAARTEDATDPPTPSSKRRLPAFLRTVRKPVR
>CP032698.1|AYG84766.1|7786419_7786734_-|hypothetical-protein
MTTYVVTIPGTLLAERTEASTETLQRALRPADPRGTRLGEEEHLEMLTFYSGSSAFSIRLEVEADDTESAERQARETVGAALRTAGYSQDEAPLGDAVITGITE

Crispr_ID: CP032698_98

• CRISPR_ID: CP032698_98
• CRISPR_location: 8138187-8138293
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of CP032698_98

Consensus_repeat	Method
GGTCCCGCTCACCGACTGAAGTCC	CRISPRCasFinder

spacers of CP032698_98

>98.1|8138211|59|CP032698|CRISPRCasFinder
GGCCGGCCCCCTCACCTACTGAGGTCCAGCCGACCCCGGCATTGACCGAAGTCCAGCCG

CRISPR arrays and Neighbor proteins around CP032698_98

CRISPR arrays

The CRISPR arrays of CP032698_98

>merge|CP032698|98|8138187-8138293|CRISPRCasFinder
GGTCCCGCTCACCGACTGAAGTCCGGCCGGCCCCCTCACCTACTGAGGTCCAGCCGACCCCGGCATTGACCGAAGTCCAGCCGGGCCCCGCTCACCGACTGAAGTCC

>CP032698|98|71|8138187-8138293|CRISPRCasFinder
GGTCCCGCTCACCGACTGAAGTCC	GGCCGGCCCCCTCACCTACTGAGGTCCAGCCGACCCCGGCATTGACCGAAGTCCAGCCG
GGCCCCGCTCACCGACTGAAGTCC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
CP032698.1|AYG85105.1|8143802_8144198_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG85090.1|8125350_8125944_+|ECF-RNA-polymerase-sigma-factor-SigC	unknown	unknown	gnl|CDD|137458
CP032698.1|AYG85108.1|8145472_8146069_-|hypothetical-protein	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG85102.1|8141612_8142161_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG85107.1|8144770_8145406_+|FMN-dependent-NADH-azoreductase-1	unknown	unknown	gnl|CDD|224103
CP032698.1|AYG85104.1|8143051_8143747_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG85094.1|8130123_8130309_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG85095.1|8130796_8132911_+|Exo-beta-1,3-glucanase	unknown	unknown	gnl|CDD|366285
CP032698.1|AYG85099.1|8138345_8139956_+|putative-ferredoxin/ferredoxin--NADP-reductase	unknown	unknown	gnl|CDD|215457
CP032698.1|AYG85106.1|8144438_8144582_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG85091.1|8126403_8127099_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG85100.1|8139997_8140687_-|putative-HTH-type-transcriptional-regulator	unknown	unknown	gnl|CDD|224228
CP032698.1|AYG85097.1|8135687_8137205_+|Putative-FAD-containing-monooxygenase-MymA	unknown	unknown	gnl|CDD|224983
CP032698.1|AYG85089.1|8124329_8125193_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG85101.1|8140768_8141380_+|putative-S-adenosyl-L-methionine-dependent-methyltransferase-TehB	unknown	unknown	gnl|CDD|379312
CP032698.1|AYG85092.1|8127725_8128088_+|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG85093.1|8128496_8128802_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG85103.1|8142518_8142878_-|hypothetical-protein	unknown	unknown	unknown
CP032698.1|AYG85096.1|8133040_8135224_+|hypothetical-protein	unknown	unknown	gnl|CDD|366285
CP032698.1|AYG85088.1|8122104_8123463_+|hypothetical-protein	unknown	unknown	gnl|CDD|377951

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
CP032698.1|AYG85090.1|8125350_8125944_+|ECF-RNA-polymerase-sigma-factor-SigC	gnl|CDD|137458	PRK09649, PRK09649, RNA polymerase sigma factor SigC; Reviewed.	8.16174e-49
CP032698.1|AYG85097.1|8135687_8137205_+|Putative-FAD-containing-monooxygenase-MymA	gnl|CDD|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.27587e-102
CP032698.1|AYG85108.1|8145472_8146069_-|hypothetical-protein	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.40773e-08
CP032698.1|AYG85101.1|8140768_8141380_+|putative-S-adenosyl-L-methionine-dependent-methyltransferase-TehB	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.55927e-17
CP032698.1|AYG85100.1|8139997_8140687_-|putative-HTH-type-transcriptional-regulator	gnl|CDD|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.55076e-07
CP032698.1|AYG85107.1|8144770_8145406_+|FMN-dependent-NADH-azoreductase-1	gnl|CDD|224103	COG1182, AcpD, Acyl carrier protein phosphodiesterase [Lipid metabolism].	2.65972e-46
CP032698.1|AYG85095.1|8130796_8132911_+|Exo-beta-1,3-glucanase	gnl|CDD|366285	pfam00754, F5_F8_type_C, F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.	9.27372e-26
CP032698.1|AYG85096.1|8133040_8135224_+|hypothetical-protein	gnl|CDD|366285	pfam00754, F5_F8_type_C, F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.	1.33307e-22
CP032698.1|AYG85088.1|8122104_8123463_+|hypothetical-protein	gnl|CDD|377951	pfam07987, DUF1775, Domain of unkown function (DUF1775). Domain found in bacteria with undetermined function. Its structure has been determined and is an immunoglobulin-like fold.	4.49078e-53
CP032698.1|AYG85099.1|8138345_8139956_+|putative-ferredoxin/ferredoxin--NADP-reductase	gnl|CDD|215457	PLN02852, PLN02852, ferredoxin-NADP+ reductase.	1.953e-138

Protein sequences

>CP032698.1|AYG85097.1|8135687_8137205_+|Putative-FAD-containing-monooxygenase-MymA
MEQQHVDVLVIGAGISGISAACHVLRDNAGTSVVVLERRARVGGTWDLFRYPGIRSDSDMSTFGFGFRPWRSARILAGGEDIRQYVEDAAADGGVLDRIRFGRRAISADFSHADGRWTVEVEDETTGGRECYSAGYLVGATGYYDYDEPYRPEFPGEADYQGTLVHPQHWPEDLDHTGKHVVVIGSGATAITLLPAMADAAASVTMLQRSPTYILALPEVDPLTAVLKKLRVPARLTHPISRTRNIALQRGSYAFCRRYPRLARKVLLGLVRARAGKNVDMRHFSPRYKPWDQRLCVVPGGDLFKVLKSGKAAIATDHIDTFTADGIRLRSGQELKADIVVTATGLSVRLLGGMALTVDGSPVDVTNRVLYKAVLLEGVPNMSLIIGYTNASWTLKADLAADYTARLLAHMRRHGHDIATPVASDADRSEFSVMGEALTSGYIARADKAMPRQGTRDPWRLWNNYYRDRAMLRSAPIEDAPLRFAKAGPSGADTAAGVQEPTRAA
>CP032698.1|AYG85096.1|8133040_8135224_+|hypothetical-protein
MSRPSSTAISPPRRAGVSLLALGALLASSLTVAFAPGAHAADTLLSQGKTATASSQEGDGYAAALAVDGNLTGTRWASQWTDQQWFQVDLGQQSTLTHAVLTWESAYGKNYEIQTSDNGTDWRTLKTVTDGDGGTDDLALSGTGRYVRMQGLARSSGYGYSLWEFQVYGTPGGGTTPPPSTGGAVKVEGSQGDWRLTVGGQPYTVKGVTWGPAASDGPKYLPDVRAMGANTIRTWGTDASSKPLLDSAAANGIRVINGFWLQPGGGPGAGGCVDYVTDTTYKANALTEFAKWVDTYKSHPATLMWNVGNESVLGLQNCYSGTQLEAERNAYTSFVNDVAKKIHTIDPDHPVTSTDAWTGAWPYYKRNAPDLDLYAMNSYSNVCKVRQDWIDGGYTKPYIITETGPAGEWEVPNDVNGIPEEPTDVQKADGYTKAWNCVTGHQGVALGATLFHYGTEHDFGGIWFNLVPNGLKRLSYYAVKQAYTGSTSGDNTPPVISNMTVSPASSAPAGGEFTVHADVRDPQGDALTYKVFLSGNYANGDKGLVEAKWRSTGNGNFAVTAPQKLGVWKVYIQAEDGHGNAGIETKSVKVVAPPVSGTNLALNQPATASSSQQSYGDCPCTPQMAVDGNSGTRWASDWSDPQWFQVDLGSSKALHKLQLVWDPAYAKSYDVQVSDDGNNWRSVYSTTAGDGDVDTVDVSATARYVRLQLTARGTTWGYSLHELGIYS
>CP032698.1|AYG85095.1|8130796_8132911_+|Exo-beta-1,3-glucanase
MVGALVSALFVLLPATTASAAPVLLSQGKPVTASSQEHYGTPASDAVDGNLTTRWSSAASDPQWIRIDLGAPTAVSQVVLRWEAAYAKAYRIELSTNGTDWSTAYSTTTGAGGTETLNVSGTARYVRMYGVSRATQYGYSLWEFQVYGSDGDGGPTLPGGGDLGPNVDIIDPSTPDIQGKLDAVFKQQESAQFGSGRHAFLFKPGTYNTINAQIGFYTQIAGLGLRPDDTTFNGDVTVDAGWAGGNATQNFWRAAENLALNPVSGTDRWAVAQASSFRRMHVKGGLNLAPAGYGWASGGYTADSKVDGTVGPYSQQQWYTRDSSIGGWTNGVWNMTFSGVEGAPANSFPEPRYTTLDTTPVSREKPFLYLDGGEMKVFAPAKRTNARGTTWANGTTPGDSIPLSKFYVVKPGATAATINAALAQGLNLLFTPGIYHVDQPIQVNRPDTIVLGLGLATIVPDNGVTAMKVADVDGVRLAGFLIDAGPVNSTTLLEIGPSGATADHSADPVTLQDVYFRIGGAGPGKATTSLVVNSNNAIIDHTWVWRADHGGGVGWDTNRADYGVRVNGNDVLATGLFVEHFNKYDVEWHGERGRTIFFQNEKAYDAPNQAAIQNGTTKGYAAYKVDDSVTTHEAWGMGSYCNYTADPSIRQDHGFEAPVKPGVKFHDLLVVSLGGNGQYEHVINDTGQATSGTATVPSTVVSYP
>CP032698.1|AYG85094.1|8130123_8130309_+|hypothetical-protein
MTVAGLKIGVASLGAVVAELLAAVSTDGLLPVTTGALALAVVVGLADRRVTDGPEGGRRLR
>CP032698.1|AYG85093.1|8128496_8128802_-|hypothetical-protein
MWDWLRLLELTTLRSARKLDWSRAVIDVSHVRAVRQGPKAGRARSSGSKHHALVDGHGVRLAVSPTGWKPYEVTQPPLLDKFLPVAHVVGGPRRRPDMSSH
>CP032698.1|AYG85092.1|8127725_8128088_+|hypothetical-protein
MTLVSTASRRVAAPLLCAVTLLVGGLAPTAPAAQASPQTDAWPCSGPAQFFAARNGSGQWTCWANAGESYAKAYGVVHWQSGHNSGLFDYECHGATGSHRFGTDDGGDLPDCTIYHVEID
>CP032698.1|AYG85091.1|8126403_8127099_-|hypothetical-protein
MNDFYAPASGMEKQPGWSWLDEYLWVSCDIISDLAEGRLGQRPLVTTVARLEPGERALAVGHATRLTWRALGDGSYMHRSVVAFGSPTFVLGSMAGSALGNSARRRAAANDAQPRWVVDGSGEITVTARKVYFGHPQCPLDLAWSGLDTIDLVAPEVFQTSFRNIRNGRQTTVQLHTPWASLLFILAAVAAFPAHPRLLGSGWLPPDFERRCTAFGRPCRPASHLLLNRGQ
>CP032698.1|AYG85090.1|8125350_8125944_+|ECF-RNA-polymerase-sigma-factor-SigC
MTTPALPCSRDESITAWALAARGGDPEAVEHFIRALQRDVRRYVTYLGADPQAADDLTQDTFLRALGSLHRFEGRSSARTWLLSIARRTVVDSLRYAAARPRLSDTDDWQSAVERVQPQGLPGFDDGIVLADLLAALPDERREAFVLTQLLGLPYADVAQLSNCPVGTVRSRVNRARAALIERLRDAERPALVGAAA
>CP032698.1|AYG85089.1|8124329_8125193_+|hypothetical-protein
MTAGGFCRTIRAAMFAAVCVLLAAVGHVLMSGTSVPWWALAAGAVATGVTGWCLAGRERGVALVMSATVAAQVLLHSSFSLAQAVVRPALPGGASFAQQWAQYLLCGSSSADLPSEAEAVRIVSDAGLGSRLASAPPGMDHMSMSSMTSMQPMSSAHMSAGWMAHDMAAMNHTASMDPMAHAAHMGSTGSMGHDMAGTSSISMLAAHLLAALLSGLWLAYGERAAFRILRVLAGWFVAPLRLVLVVPAPPHRPRTPSCRHRTADVLRQLLLARAITSRGPPMRTAVV
>CP032698.1|AYG85088.1|8122104_8123463_+|hypothetical-protein
MGLSRTVRGVRATVFAAMCVLLAVGGHRLASGELPPLWADGAGFLGIFVLGFLLGGRERSLAGIAGATLAGQAGLHFTYEAARPRTALAMHGMRMTHAHAMTPHAVAAHTAATLVVSWWLRRGEAALWSLLRRAVAFVPGLAAWWRARTDTIPDPARCGPVRGSGAAPRALRQVLLRYAVSRRGPPSASVIRADPNPTFSFGVPLMIHIRTVVRRALRRTALAAALASAGVLAAAGVAFAHVTVHPGSYAKGATDGVLTFRVPNEEDNASTTKVQVFVPTDHPVLGVLVAPMPGWTAQVTTAKLKTPIKTDDGSITEAASEITWTGGKIDPGQYQDFNVAFGQLPDDTDQLSFKTLQTYSDGKTVRWIDEAKQGQPEPANPAPVLSLTKSAAGDGGAASASPSVSPAAPKAATASSSDGAARGLGIAGLVVGVLGLTAAVVAIRRGRRSSEV
>CP032698.1|AYG85099.1|8138345_8139956_+|putative-ferredoxin/ferredoxin--NADP-reductase
MPYVVTRSCCADASCVLACPVNCIHPAPGEPGFGTTEMLYVDPRTCVDCGACTTACPVDALKPHTALDEAELPFLELNASYYKENAHADRAPMYVVPRQRRLPQGELSVAVVGAGPAGLFAADELLRHAGVRVTVYDRLPTPYGLARAGVAPDHQDTKRVTELFRAIESQPAFGYRLGVEVGTDVTHADLMREHHAVIYAVGAATDKRLGIDGEDLPGSICATDFVAWYNGHPDRAHDDHDLGVDRAVVIGNGNVALDVARVLTADPGALARTDISDRALAALRTSTIREVVLLGRRGPAQAAFTVPELLALGALKDVDVCVEGWPEGLSPAATEKTRLLSELAARTPVQGRRRIVLRFLTSPVRIIGDGRVRALEVTSTTLHTDDDGTVTARPTGDRRTLETGLVLRCVGYRARPVPGLPFDAETATIPHVAGRVEPGVYVAGWVKRGPTGFIGTNKTCAQETVASLLDDFAAGRLARPLSTVTAAGNALGLEDWRSIDRVERAAGEAQGRPRVKLTDTESLYRAAARSVPAVRG
>CP032698.1|AYG85100.1|8139997_8140687_-|putative-HTH-type-transcriptional-regulator
MADRTGGEPQIDGRSTRWDEHKARRQVDLVDAAVALIEEEGTRFRVQRLAERVGLPRSVLYRHFKDRAALDELIRRRVVDSFMRRMEPTLTFEGTVEDAVHRVVGAHLDWVAQHPRLYAYMGVAEHAMGDGSLVADTKTAIALMLSERFGEVLKALGVPQAPIRSVAVGIVGFVDTAVNQWAHDERREQSEEELRAMLCRSVWAILDATLRDLGVEVSPQQRVSDLGPH
>CP032698.1|AYG85101.1|8140768_8141380_+|putative-S-adenosyl-L-methionine-dependent-methyltransferase-TehB
MSRWQELTGGTSGDEYAARFEALARGGKDVHGEAAFCAALVAPGARVLDAGCGTGRVMIRLAELGYDCVGVDLDASMLDVARERAPQLPWFQADLAAFDPTPLGVAADFDLVVAAGNVLPLVAPGTEATVVARLAAALRPGGLLVAGFGLDAAHLPVPPALTLAQYDLHCAAAGLTPTGRFATWDAAPYDGGGYAVSVHRRDR
>CP032698.1|AYG85102.1|8141612_8142161_-|hypothetical-protein
MIVVHGHVKTTKMIHVIAAVCLTVAATAGAAPSHTGSAAPAVRQAADETCTPETDSYSADRWTSARWKSCLGTYGGPHGSFQAKCWGGQTIGWSQKNCRVSGRFEIRDGQKKVVKSGSFGLSYNGLVDEPTVTTSAFRFNCDGRAHGRFTFKTSGTKAKLSGNYSHYEAAKIPDATVSHPMC
>CP032698.1|AYG85103.1|8142518_8142878_-|hypothetical-protein
MDIRKKAATTVGALALAFAGILGAAGQSAAASNGQQIVFADTRGDTYSVYLVGTNQNGEHATICFNTPNRNTYVGGWWWKGEVSYIGWAGANCTGASRGSYRATVPTYQTDTDWYTISN
>CP032698.1|AYG85104.1|8143051_8143747_-|hypothetical-protein
MQSVLTAVSSESRSETACRNVPLRAILDGTAEPVSADIPSPRKITGARLLLRIHQSEGAPSPRPYRRPADARQAPATDPFTARPRPSQRAPPVAHALASAAPQQVLGHSLPGDGGCLHRSCEGVRSLRVVRERVTALFGPLCPPGLGVGLLAPPSNVCEDGRRAPPGRHPDRPGRWHGGSPRGRPAATQRPLPRWSPAPAAAPRGHRPARRAGPCGGPGDRAAPTSYRLHL
>CP032698.1|AYG85105.1|8143802_8144198_-|hypothetical-protein
MFVRTESLPQAPQQHMTVRVHTPIGSAVVVWRGHPGEADGQHLIEWTVDADINWGRNSRPAAASEPELRQEGDQVVMCGRLHLTADGASYLQMGPWSVLFDQASPIPSSMSESWVEISVATQRVALYPCRI
>CP032698.1|AYG85106.1|8144438_8144582_+|hypothetical-protein
MVSSSTATGLDLPEPQETDLDGEEAHHLLVTAHADICRPLDHGLFIP
>CP032698.1|AYG85107.1|8144770_8145406_+|FMN-dependent-NADH-azoreductase-1
MATLLHIDSSAFAGQASTSRAVTEAFRRTWLEEHPGGEVIYRDLAAQPVPHITADAHTAGLLDPAEHTEEQARAFAERLALITELEAADAVVIGAPMYNFSVPSSLKAWLDQVILMGRTAGSPESKVKGTPVTVVTSRGGSYAPGTPRAPHEHVLNYLESVLSMIFEMEATFIVADLTLAAHIPALEHLVPLGEQSRADAFEAAANAARAA
>CP032698.1|AYG85108.1|8145472_8146069_-|hypothetical-protein
MPEAPQRPPLRADARRNVEKLRQAAADAFSEHGLDTPLETIAKLAGVSVGTIYNRFGSRDALLDQVVNELADRHVRAAMAIADGAAGSAWEKLQTYVEAICQAQADDPAFNDAFSRRYPNAPALKAVCDRSLAFATDLAAGARAEGVLREDAQMDDIARFFQVNGDLVRAGDDAGRRRVLALLFEGLRARTGSRPLPS

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	4648745-4648764	0	1.0
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	4008401-4008434	0	1.0
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	3568167-3568195	0	1.0
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	3919351-3919379	0	1.0
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	4787738-4787766	0	1.0
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	4787853-4787881	0	1.0
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	5853443-5853471	0	1.0
CP032698_34	34.9|4014032|20|CP032698|PILER-CR	4014032-4014051	20	CP032698.1	4147550-4147569	0	1.0
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	5038006-5038035	0	1.0
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	5038001-5038031	0	1.0
CP032698_47	47.1|4480725|33|CP032698|PILER-CR,CRT	4480725-4480757	33	CP032698.1	5406186-5406218	0	1.0
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	3568282-3568312	0	1.0
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	5788926-5788956	0	1.0
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	5853557-5853587	0	1.0
CP032698_59	59.1|5075217|32|CP032698|CRISPRCasFinder	5075217-5075248	32	CP032698.1	4801238-4801269	0	1.0
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	5862102-5862136	0	1.0
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	CP032698.1	3983463-3983493	0	1.0
CP032698_70	70.1|5488566|21|CP032698|PILER-CR	5488566-5488586	21	CP032698.1	5821764-5821784	0	1.0
CP032698_79	79.3|6011683|32|CP032698|PILER-CR	6011683-6011714	32	CP032698.1	3550412-3550443	0	1.0
CP032698_82	82.1|6018962|55|CP032698|CRISPRCasFinder	6018962-6019016	55	CP032698.1	4189655-4189709	0	1.0
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	CP032698.1	3568166-3568197	1	0.969
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	CP032698.1	3919349-3919380	1	0.969
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	CP032698.1	4787737-4787768	1	0.969
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	CP032698.1	4787852-4787883	1	0.969
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	CP032698.1	5853441-5853472	1	0.969
CP032698_5	5.1|1822206|50|CP032698|CRISPRCasFinder	1822206-1822255	50	CP032698.1	4189657-4189706	1	0.98
CP032698_8	8.1|2471199|28|CP032698|CRISPRCasFinder	2471199-2471226	28	CP032698.1	4502923-4502950	1	0.964
CP032698_8	8.1|2471199|28|CP032698|CRISPRCasFinder	2471199-2471226	28	CP032698.1	5633102-5633129	1	0.964
CP032698_12	12.1|2818688|32|CP032698|CRISPRCasFinder	2818688-2818719	32	CP032698.1	5514204-5514235	1	0.969
CP032698_12	12.1|2818688|32|CP032698|CRISPRCasFinder	2818688-2818719	32	CP032698.1	6319299-6319330	1	0.969
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	3092489-3092508	1	0.95
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	3092590-3092609	1	0.95
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	6182534-6182553	1	0.95
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3550353-3550386	1	0.971
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3756059-3756092	1	0.971
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	5853380-5853413	1	0.971
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	6475245-6475278	1	0.971
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	7052559-7052592	1	0.971
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	3568454-3568489	1	0.972
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	3444539-3444567	1	0.966
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	3568283-3568311	1	0.966
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	3892463-3892491	1	0.966
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	5788927-5788955	1	0.966
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	5853558-5853586	1	0.966
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	1693722-1693754	1	0.97
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	4787793-4787825	1	0.97
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	4787908-4787940	1	0.97
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	4801181-4801213	1	0.97
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	4967577-4967609	1	0.97
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	5445818-5445850	1	0.97
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	2616828-2616847	1	0.95
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	3157085-3157104	1	0.95
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	4916369-4916388	1	0.95
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	5847553-5847572	1	0.95
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	6903042-6903061	1	0.95
CP032698_34	34.4|4013847|36|CP032698|CRT	4013847-4013882	36	CP032698.1	3585769-3585804	1	0.972
CP032698_34	34.4|4013847|36|CP032698|CRT	4013847-4013882	36	CP032698.1	4607070-4607105	1	0.972
CP032698_34	34.4|4013847|36|CP032698|CRT	4013847-4013882	36	CP032698.1	5035086-5035121	1	0.972
CP032698_34	34.9|4014032|20|CP032698|PILER-CR	4014032-4014051	20	CP032698.1	5038003-5038022	1	0.95
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	3550354-3550383	1	0.967
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	3568460-3568489	1	0.967
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	6475246-6475275	1	0.967
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	3585726-3585753	1	0.964
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	4967518-4967545	1	0.964
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	5038002-5038029	1	0.964
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	3568282-3568311	1	0.967
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	5788927-5788956	1	0.967
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	5847497-5847526	1	0.967
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	5853558-5853587	1	0.967
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	3568286-3568316	1	0.968
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	5788922-5788952	1	0.968
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	5847492-5847522	1	0.968
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	5853553-5853583	1	0.968
CP032698_42	42.1|4174644|38|CP032698|CRT	4174644-4174681	38	CP032698.1	4008396-4008433	1	0.974
CP032698_43	43.1|4204779|53|CP032698|CRISPRCasFinder	4204779-4204831	53	CP032698.1	4480558-4480610	1	0.981
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	3568283-3568315	1	0.97
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	4603250-4603282	1	0.97
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	5788923-5788955	1	0.97
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	5853554-5853586	1	0.97
CP032698_47	47.1|4480725|33|CP032698|PILER-CR,CRT	4480725-4480757	33	CP032698.1	5627692-5627724	1	0.97
CP032698_47	47.1|4480725|33|CP032698|PILER-CR,CRT	4480725-4480757	33	CP032698.1	5821766-5821798	1	0.97
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	3568165-3568196	1	0.969
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	3568281-3568312	1	0.969
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	3919350-3919381	1	0.969
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	4776924-4776955	1	0.969
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	4787736-4787767	1	0.969
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	4787851-4787882	1	0.969
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	5788926-5788957	1	0.969
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	5853442-5853473	1	0.969
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	5853557-5853588	1	0.969
CP032698_47	47.3|4480838|36|CP032698|PILER-CR,CRT	4480838-4480873	36	CP032698.1	4422484-4422519	1	0.972
CP032698_47	47.3|4480838|36|CP032698|PILER-CR,CRT	4480838-4480873	36	CP032698.1	5090837-5090872	1	0.972
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	1978514-1978534	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	2474772-2474792	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	2936131-2936151	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3362388-3362408	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3362538-3362558	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3795488-3795508	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3795549-3795569	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3795610-3795630	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3795671-3795691	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3795732-3795752	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3795793-3795813	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3795854-3795874	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3795915-3795935	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3911154-3911174	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3911213-3911233	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3926214-3926234	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4189880-4189900	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4189938-4189958	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4204611-4204631	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4422498-4422518	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4472221-4472241	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4502915-4502935	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4801193-4801213	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4912526-4912546	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5936490-5936510	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5936605-5936625	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6182593-6182613	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6394837-6394857	1	0.952
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6519300-6519320	1	0.952
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	3157232-3157262	1	0.968
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	3568166-3568196	1	0.968
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	3919350-3919380	1	0.968
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	4189824-4189854	1	0.968
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	4787737-4787767	1	0.968
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	4787852-4787882	1	0.968
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	5038005-5038035	1	0.968
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	5763950-5763980	1	0.968
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	5853442-5853472	1	0.968
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	6364975-6365005	1	0.968
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	6394767-6394797	1	0.968
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	3795443-3795466	1	0.958
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	3795504-3795527	1	0.958
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	3795565-3795588	1	0.958
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	3795626-3795649	1	0.958
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	3795687-3795710	1	0.958
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	3795748-3795771	1	0.958
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	3795809-3795832	1	0.958
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	3795870-3795893	1	0.958
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	3795931-3795954	1	0.958
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	4008414-4008437	1	0.958
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	5420278-5420301	1	0.958
CP032698_55	55.3|4866586|37|CP032698|PILER-CR	4866586-4866622	37	CP032698.1	3838628-3838664	1	0.973
CP032698_56	56.1|4878703|37|CP032698|CRT	4878703-4878739	37	CP032698.1	4502972-4503008	1	0.973
CP032698_58	58.1|5049170|37|CP032698|PILER-CR,CRT	5049170-5049206	37	CP032698.1	1693722-1693758	1	0.973
CP032698_58	58.1|5049170|37|CP032698|PILER-CR,CRT	5049170-5049206	37	CP032698.1	3568222-3568258	1	0.973
CP032698_58	58.1|5049170|37|CP032698|PILER-CR,CRT	5049170-5049206	37	CP032698.1	5853610-5853646	1	0.973
CP032698_59	59.1|5075217|32|CP032698|CRISPRCasFinder	5075217-5075248	32	CP032698.1	5764006-5764037	1	0.969
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	1693722-1693756	1	0.971
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	3818733-3818767	1	0.971
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	4136293-4136327	1	0.971
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	4967575-4967609	1	0.971
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	5445818-5445852	1	0.971
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	5488665-5488699	1	0.971
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	5853612-5853646	1	0.971
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	3838632-3838663	1	0.969
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	6088934-6088965	1	0.969
CP032698_62	62.5|5196207|33|CP032698|CRT	5196207-5196239	33	CP032698.1	5633160-5633192	1	0.97
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	CP032698.1	5764008-5764038	1	0.968
CP032698_70	70.1|5488566|21|CP032698|PILER-CR	5488566-5488586	21	CP032698.1	3795379-3795399	1	0.952
CP032698_70	70.1|5488566|21|CP032698|PILER-CR	5488566-5488586	21	CP032698.1	4020197-4020217	1	0.952
CP032698_70	70.1|5488566|21|CP032698|PILER-CR	5488566-5488586	21	CP032698.1	5789016-5789036	1	0.952
CP032698_70	70.1|5488566|21|CP032698|PILER-CR	5488566-5488586	21	CP032698.1	5964751-5964771	1	0.952
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	5764005-5764036	1	0.969
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	6295097-6295128	1	0.969
CP032698_77	77.2|5941644|31|CP032698|PILER-CR	5941644-5941674	31	CP032698.1	4776867-4776897	1	0.968
CP032698_79	79.1|6011567|33|CP032698|PILER-CR	6011567-6011599	33	CP032698.1	1978573-1978605	1	0.97
CP032698_79	79.2|6011623|37|CP032698|PILER-CR	6011623-6011659	37	CP032698.1	3675756-3675792	1	0.973
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	3568166-3568196	1	0.968
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	3919350-3919380	1	0.968
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	4787737-4787767	1	0.968
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	4787852-4787882	1	0.968
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	5038005-5038035	1	0.968
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	5853442-5853472	1	0.968
CP032698_85	85.4|6253315|31|CP032698|CRT	6253315-6253345	31	CP032698.1	3366364-3366394	1	0.968
CP032698_85	85.4|6253315|31|CP032698|CRT	6253315-6253345	31	CP032698.1	3919465-3919495	1	0.968
CP032698_85	85.4|6253315|31|CP032698|CRT	6253315-6253345	31	CP032698.1	5831472-5831502	1	0.968
CP032698_89	89.2|6739334|35|CP032698|CRT	6739334-6739368	35	CP032698.1	3282330-3282364	1	0.971
CP032698_89	89.4|6739450|35|CP032698|CRT	6739450-6739484	35	CP032698.1	3282330-3282364	1	0.971
CP032698_94	94.2|7161791|17|CP032698|PILER-CR	7161791-7161807	17	CP032698.1	1969192-1969208	1	0.941
CP032698_97	97.1|7776827|17|CP032698|CRISPRCasFinder	7776827-7776843	17	CP032698.1	1932097-1932113	1	0.941
CP032698_97	97.1|7776827|17|CP032698|CRISPRCasFinder	7776827-7776843	17	CP032698.1	2471280-2471296	1	0.941
CP032698_2	2.1|1292446|22|CP032698|PILER-CR	1292446-1292467	22	CP032698.1	2474886-2474907	2	0.909
CP032698_2	2.1|1292446|22|CP032698|PILER-CR	1292446-1292467	22	CP032698.1	2967202-2967223	2	0.909
CP032698_2	2.1|1292446|22|CP032698|PILER-CR	1292446-1292467	22	CP032698.1	2967284-2967305	2	0.909
CP032698_2	2.1|1292446|22|CP032698|PILER-CR	1292446-1292467	22	CP032698.1	3662319-3662340	2	0.909
CP032698_2	2.1|1292446|22|CP032698|PILER-CR	1292446-1292467	22	CP032698.1	3756074-3756095	2	0.909
CP032698_2	2.1|1292446|22|CP032698|PILER-CR	1292446-1292467	22	CP032698.1	3847532-3847553	2	0.909
CP032698_2	2.1|1292446|22|CP032698|PILER-CR	1292446-1292467	22	CP032698.1	3992522-3992543	2	0.909
CP032698_2	2.1|1292446|22|CP032698|PILER-CR	1292446-1292467	22	CP032698.1	4008398-4008419	2	0.909
CP032698_2	2.1|1292446|22|CP032698|PILER-CR	1292446-1292467	22	CP032698.1	5853395-5853416	2	0.909
CP032698_2	2.3|1292421|35|CP032698|CRISPRCasFinder	1292421-1292455	35	CP032698.1	3662306-3662340	2	0.943
CP032698_2	2.3|1292421|35|CP032698|CRISPRCasFinder	1292421-1292455	35	CP032698.1	4008398-4008432	2	0.943
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	CP032698.1	3568282-3568313	2	0.938
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	CP032698.1	5788925-5788956	2	0.938
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	CP032698.1	5853556-5853587	2	0.938
CP032698_5	5.1|1822206|50|CP032698|CRISPRCasFinder	1822206-1822255	50	CP032698.1	2935685-2935734	2	0.96
CP032698_5	5.1|1822206|50|CP032698|CRISPRCasFinder	1822206-1822255	50	CP032698.1	3756222-3756271	2	0.96
CP032698_8	8.1|2471199|28|CP032698|CRISPRCasFinder	2471199-2471226	28	CP032698.1	5789014-5789041	2	0.929
CP032698_9	9.1|2513596|34|CP032698|PILER-CR	2513596-2513629	34	CP032698.1	5503170-5503203	2	0.941
CP032698_9	9.1|2513596|34|CP032698|PILER-CR	2513596-2513629	34	CP032698.1	5514146-5514179	2	0.941
CP032698_12	12.1|2818688|32|CP032698|CRISPRCasFinder	2818688-2818719	32	CP032698.1	3677591-3677622	2	0.938
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	4916325-4916344	2	0.9
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	5055052-5055071	2	0.9
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	5069742-5069761	2	0.9
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	5145799-5145818	2	0.9
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	5343067-5343086	2	0.9
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	5843946-5843965	2	0.9
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	5999429-5999448	2	0.9
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	7161813-7161832	2	0.9
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	CP032698.1	8306393-8306412	2	0.9
CP032698_17	17.1|3328038|48|CP032698|CRISPRCasFinder	3328038-3328085	48	CP032698.1	5145610-5145657	2	0.958
CP032698_18	18.1|3355695|29|CP032698|CRISPRCasFinder	3355695-3355723	29	CP032698.1	3282444-3282472	2	0.931
CP032698_18	18.1|3355695|29|CP032698|CRISPRCasFinder	3355695-3355723	29	CP032698.1	5313452-5313480	2	0.931
CP032698_18	18.1|3355695|29|CP032698|CRISPRCasFinder	3355695-3355723	29	CP032698.1	5514151-5514179	2	0.931
CP032698_18	18.2|3355751|29|CP032698|CRISPRCasFinder	3355751-3355779	29	CP032698.1	3554478-3554506	2	0.931
CP032698_18	18.2|3355751|29|CP032698|CRISPRCasFinder	3355751-3355779	29	CP032698.1	3961638-3961666	2	0.931
CP032698_18	18.2|3355751|29|CP032698|CRISPRCasFinder	3355751-3355779	29	CP032698.1	5145970-5145998	2	0.931
CP032698_18	18.2|3355751|29|CP032698|CRISPRCasFinder	3355751-3355779	29	CP032698.1	5158304-5158332	2	0.931
CP032698_18	18.2|3355751|29|CP032698|CRISPRCasFinder	3355751-3355779	29	CP032698.1	6365031-6365059	2	0.931
CP032698_18	18.2|3355751|29|CP032698|CRISPRCasFinder	3355751-3355779	29	CP032698.1	6786888-6786916	2	0.931
CP032698_18	18.3|3355706|20|CP032698|PILER-CR	3355706-3355725	20	CP032698.1	3282452-3282471	2	0.9
CP032698_18	18.3|3355706|20|CP032698|PILER-CR	3355706-3355725	20	CP032698.1	5313460-5313479	2	0.9
CP032698_18	18.3|3355706|20|CP032698|PILER-CR	3355706-3355725	20	CP032698.1	5514152-5514171	2	0.9
CP032698_18	18.3|3355706|20|CP032698|PILER-CR	3355706-3355725	20	CP032698.1	5520055-5520074	2	0.9
CP032698_18	18.4|3355762|28|CP032698|PILER-CR	3355762-3355789	28	CP032698.1	3554478-3554505	2	0.929
CP032698_18	18.4|3355762|28|CP032698|PILER-CR	3355762-3355789	28	CP032698.1	3832974-3833001	2	0.929
CP032698_18	18.4|3355762|28|CP032698|PILER-CR	3355762-3355789	28	CP032698.1	5145970-5145997	2	0.929
CP032698_18	18.4|3355762|28|CP032698|PILER-CR	3355762-3355789	28	CP032698.1	5158305-5158332	2	0.929
CP032698_18	18.4|3355762|28|CP032698|PILER-CR	3355762-3355789	28	CP032698.1	6786889-6786916	2	0.929
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	1822045-1822078	2	0.941
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3362230-3362263	2	0.941
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3795491-3795524	2	0.941
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3795552-3795585	2	0.941
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3795613-3795646	2	0.941
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3795674-3795707	2	0.941
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3795735-3795768	2	0.941
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3795796-3795829	2	0.941
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3795857-3795890	2	0.941
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	CP032698.1	3795918-3795951	2	0.941
CP032698_21	21.1|3487093|34|CP032698|CRISPRCasFinder	3487093-3487126	34	CP032698.1	3818731-3818764	2	0.941
CP032698_21	21.1|3487093|34|CP032698|CRISPRCasFinder	3487093-3487126	34	CP032698.1	3992622-3992655	2	0.941
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	3756060-3756095	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	3795488-3795523	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	3795549-3795584	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	3795610-3795645	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	3795671-3795706	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	3795732-3795767	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	3795793-3795828	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	3795854-3795889	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	3795915-3795950	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	4008398-4008433	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	4189880-4189915	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	4422483-4422518	2	0.944
CP032698_23	23.2|3570331|36|CP032698|PILER-CR	3570331-3570366	36	CP032698.1	4916367-4916402	2	0.944
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	2936191-2936219	2	0.931
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	3157233-3157261	2	0.931
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	4189825-4189853	2	0.931
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	4776925-4776953	2	0.931
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	5763951-5763979	2	0.931
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	6295099-6295127	2	0.931
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	6364976-6365004	2	0.931
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	CP032698.1	6394768-6394796	2	0.931
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	2936131-2936163	2	0.939
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	3327864-3327896	2	0.939
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	3568222-3568254	2	0.939
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	3838673-3838705	2	0.939
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	4020184-4020216	2	0.939
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	4607013-4607045	2	0.939
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	5326503-5326535	2	0.939
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	5627693-5627725	2	0.939
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	5862102-5862134	2	0.939
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	CP032698.1	6554566-6554598	2	0.939
CP032698_27	27.3|3746550|35|CP032698|CRT	3746550-3746584	35	CP032698.1	5964623-5964657	2	0.943
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	1822048-1822067	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	3675885-3675904	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	3756062-3756081	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	3880351-3880370	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	3992510-3992529	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	4020198-4020217	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	4502929-4502948	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	4844040-4844059	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	5012388-5012407	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	5054925-5054944	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	5514260-5514279	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	5964524-5964543	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	5964581-5964600	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	5964638-5964657	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	5964695-5964714	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	5964752-5964771	2	0.9
CP032698_27	27.5|3746576|20|CP032698|PILER-CR	3746576-3746595	20	CP032698.1	6047979-6047998	2	0.9
CP032698_34	34.4|4013847|36|CP032698|CRT	4013847-4013882	36	CP032698.1	3838629-3838664	2	0.944
CP032698_34	34.5|4013903|37|CP032698|CRT	4013903-4013939	37	CP032698.1	3756001-3756037	2	0.946
CP032698_34	34.9|4014032|20|CP032698|PILER-CR	4014032-4014051	20	CP032698.1	3585727-3585746	2	0.9
CP032698_34	34.9|4014032|20|CP032698|PILER-CR	4014032-4014051	20	CP032698.1	3892460-3892479	2	0.9
CP032698_34	34.9|4014032|20|CP032698|PILER-CR	4014032-4014051	20	CP032698.1	5847494-5847513	2	0.9
CP032698_34	34.10|4014090|20|CP032698|PILER-CR	4014090-4014109	20	CP032698.1	5999384-5999403	2	0.9
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	3795494-3795523	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	3795555-3795584	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	3795616-3795645	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	3795677-3795706	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	3795738-3795767	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	3795799-3795828	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	3795860-3795889	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	3795921-3795950	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	4008404-4008433	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	4136299-4136328	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	4189886-4189915	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	4422483-4422512	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	4430419-4430448	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	4959081-4959110	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	5445824-5445853	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	6260757-6260786	2	0.933
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP032698.1	7052560-7052589	2	0.933
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	3568172-3568199	2	0.929
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	3568288-3568315	2	0.929
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	3919347-3919374	2	0.929
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	4787743-4787770	2	0.929
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	4787858-4787885	2	0.929
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	5788923-5788950	2	0.929
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	5847493-5847520	2	0.929
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	5853439-5853466	2	0.929
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	CP032698.1	5853554-5853581	2	0.929
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	3157232-3157261	2	0.933
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	3568166-3568195	2	0.933
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	3919351-3919380	2	0.933
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	4189824-4189853	2	0.933
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	4787737-4787766	2	0.933
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	4787852-4787881	2	0.933
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	4967522-4967551	2	0.933
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	5763950-5763979	2	0.933
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	5853443-5853472	2	0.933
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	6364975-6365004	2	0.933
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	CP032698.1	6394768-6394797	2	0.933
CP032698_38	38.2|4133580|30|CP032698|PILER-CR	4133580-4133609	30	CP032698.1	3157348-3157377	2	0.933
CP032698_38	38.2|4133580|30|CP032698|PILER-CR	4133580-4133609	30	CP032698.1	3662307-3662336	2	0.933
CP032698_38	38.2|4133580|30|CP032698|PILER-CR	4133580-4133609	30	CP032698.1	4008402-4008431	2	0.933
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	1230391-1230421	2	0.935
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	3157236-3157266	2	0.935
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	3568170-3568200	2	0.935
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	3892458-3892488	2	0.935
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	3919346-3919376	2	0.935
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	4787741-4787771	2	0.935
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	4787856-4787886	2	0.935
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	4967517-4967547	2	0.935
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	5763954-5763984	2	0.935
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	CP032698.1	5853438-5853468	2	0.935
CP032698_39	39.1|4136122|49|CP032698|CRISPRCasFinder	4136122-4136170	49	CP032698.1	2628404-2628452	2	0.959
CP032698_42	42.1|4174644|38|CP032698|CRT	4174644-4174681	38	CP032698.1	3568452-3568489	2	0.947
CP032698_42	42.1|4174644|38|CP032698|CRT	4174644-4174681	38	CP032698.1	3847530-3847567	2	0.947
CP032698_42	42.1|4174644|38|CP032698|CRT	4174644-4174681	38	CP032698.1	5853381-5853418	2	0.947
CP032698_42	42.1|4174644|38|CP032698|CRT	4174644-4174681	38	CP032698.1	7052560-7052597	2	0.947
CP032698_42	42.3|4174756|36|CP032698|CRT	4174756-4174791	36	CP032698.1	4801236-4801271	2	0.944
CP032698_42	42.5|4174757|36|CP032698|PILER-CR	4174757-4174792	36	CP032698.1	4801236-4801271	2	0.944
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	3157233-3157265	2	0.939
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	3568167-3568199	2	0.939
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	3919347-3919379	2	0.939
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	4787738-4787770	2	0.939
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	4787853-4787885	2	0.939
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	5763951-5763983	2	0.939
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	5853439-5853471	2	0.939
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	CP032698.1	6394764-6394796	2	0.939
CP032698_46	46.1|4443766|53|CP032698|CRISPRCasFinder	4443766-4443818	53	CP032698.1	2853239-2853291	2	0.962
CP032698_47	47.1|4480725|33|CP032698|PILER-CR,CRT	4480725-4480757	33	CP032698.1	4422487-4422519	2	0.939
CP032698_47	47.1|4480725|33|CP032698|PILER-CR,CRT	4480725-4480757	33	CP032698.1	5090837-5090869	2	0.939
CP032698_47	47.1|4480725|33|CP032698|PILER-CR,CRT	4480725-4480757	33	CP032698.1	5964623-5964655	2	0.939
CP032698_47	47.1|4480725|33|CP032698|PILER-CR,CRT	4480725-4480757	33	CP032698.1	6182582-6182614	2	0.939
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	1978457-1978488	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	3157231-3157262	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	3892462-3892493	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	4189823-4189854	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	4967521-4967552	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	5038005-5038036	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	5326218-5326249	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	5627806-5627837	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	5652387-5652418	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	5763949-5763980	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	6364974-6365005	2	0.938
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	CP032698.1	6394767-6394798	2	0.938
CP032698_47	47.3|4480838|36|CP032698|PILER-CR,CRT	4480838-4480873	36	CP032698.1	5406183-5406218	2	0.944
CP032698_47	47.3|4480838|36|CP032698|PILER-CR,CRT	4480838-4480873	36	CP032698.1	5488664-5488699	2	0.944
CP032698_47	47.3|4480838|36|CP032698|PILER-CR,CRT	4480838-4480873	36	CP032698.1	5821763-5821798	2	0.944
CP032698_47	47.3|4480838|36|CP032698|PILER-CR,CRT	4480838-4480873	36	CP032698.1	5862101-5862136	2	0.944
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	1539395-1539415	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	1539546-1539566	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	1693722-1693742	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	1693837-1693857	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	1807861-1807881	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	1978688-1978708	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	2624545-2624565	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	2668957-2668977	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	2818744-2818764	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	2967359-2967379	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	2967439-2967459	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3064834-3064854	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3282270-3282290	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3318447-3318467	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3355544-3355564	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3568222-3568242	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3568454-3568474	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3675755-3675775	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3675871-3675891	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3677546-3677566	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3756016-3756036	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3795427-3795447	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3838685-3838705	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3892530-3892550	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3945749-3945769	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	3951945-3951965	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4136293-4136313	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4147733-4147753	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4163240-4163260	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4163297-4163317	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4430413-4430433	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4472278-4472298	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4492173-4492193	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4496587-4496607	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4607013-4607033	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4638486-4638506	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4638543-4638563	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4638600-4638620	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4777220-4777240	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4787793-4787813	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4787908-4787928	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4840662-4840682	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4959096-4959116	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	4967589-4967609	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5012401-5012421	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5105458-5105478	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5145913-5145933	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5306826-5306846	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5306970-5306990	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5342971-5342991	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5420262-5420282	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5445702-5445722	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5445818-5445838	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5478075-5478095	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5478189-5478209	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5633117-5633137	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5747222-5747242	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5761379-5761399	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5789029-5789049	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5860187-5860207	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	5956293-5956313	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6182713-6182733	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6241510-6241530	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6241656-6241676	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6261928-6261948	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6365088-6365108	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6394663-6394683	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6541527-6541547	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6554578-6554598	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6635952-6635972	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6902878-6902898	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6956943-6956963	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6963475-6963495	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6963634-6963654	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	6984658-6984678	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	7020950-7020970	2	0.905
CP032698_50	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	CP032698.1	7240663-7240683	2	0.905
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	1230387-1230417	2	0.935
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	3157288-3157318	2	0.935
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	3550300-3550330	2	0.935
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	3568052-3568082	2	0.935
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	3568398-3568428	2	0.935
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	3702705-3702735	2	0.935
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	3892462-3892492	2	0.935
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	4603249-4603279	2	0.935
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	4776924-4776954	2	0.935
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	5847496-5847526	2	0.935
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	CP032698.1	6475136-6475166	2	0.935
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	3362227-3362250	2	0.917
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	4204592-4204615	2	0.917
CP032698_53	53.2|4844171|24|CP032698|PILER-CR	4844171-4844194	24	CP032698.1	5445834-5445857	2	0.917
CP032698_55	55.3|4866586|37|CP032698|PILER-CR	4866586-4866622	37	CP032698.1	1821876-1821912	2	0.946
CP032698_55	55.3|4866586|37|CP032698|PILER-CR	4866586-4866622	37	CP032698.1	3585768-3585804	2	0.946
CP032698_55	55.3|4866586|37|CP032698|PILER-CR	4866586-4866622	37	CP032698.1	4607070-4607106	2	0.946
CP032698_55	55.3|4866586|37|CP032698|PILER-CR	4866586-4866622	37	CP032698.1	5069726-5069762	2	0.946
CP032698_58	58.1|5049170|37|CP032698|PILER-CR,CRT	5049170-5049206	37	CP032698.1	3327860-3327896	2	0.946
CP032698_59	59.1|5075217|32|CP032698|CRISPRCasFinder	5075217-5075248	32	CP032698.1	3568052-3568083	2	0.938
CP032698_59	59.1|5075217|32|CP032698|CRISPRCasFinder	5075217-5075248	32	CP032698.1	3568398-3568429	2	0.938
CP032698_59	59.1|5075217|32|CP032698|CRISPRCasFinder	5075217-5075248	32	CP032698.1	3983464-3983495	2	0.938
CP032698_59	59.1|5075217|32|CP032698|CRISPRCasFinder	5075217-5075248	32	CP032698.1	5445762-5445793	2	0.938
CP032698_59	59.1|5075217|32|CP032698|CRISPRCasFinder	5075217-5075248	32	CP032698.1	6475135-6475166	2	0.938
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	3282270-3282304	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	3327862-3327896	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	3467242-3467276	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	3568222-3568256	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	3838671-3838705	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	3919405-3919439	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	3961695-3961729	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	5326501-5326535	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	5420262-5420296	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	5503169-5503203	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	5843887-5843921	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	5853497-5853531	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	5956279-5956313	2	0.943
CP032698_59	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	CP032698.1	6554564-6554598	2	0.943
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	1821880-1821911	2	0.938
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	3318507-3318538	2	0.938
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	3585772-3585803	2	0.938
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	4607071-4607102	2	0.938
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	5035089-5035120	2	0.938
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	5091010-5091041	2	0.938
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	5478234-5478265	2	0.938
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	5520107-5520138	2	0.938
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	CP032698.1	5633049-5633080	2	0.938
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	CP032698.1	2052181-2052210	2	0.933
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	CP032698.1	5343069-5343098	2	0.933
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	CP032698.1	1978574-1978604	2	0.935
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	CP032698.1	3550468-3550498	2	0.935
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	CP032698.1	3568054-3568084	2	0.935
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	CP032698.1	3568400-3568430	2	0.935
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	CP032698.1	4603251-4603281	2	0.935
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	CP032698.1	4801237-4801267	2	0.935
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	CP032698.1	5445764-5445794	2	0.935
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	CP032698.1	6475134-6475164	2	0.935
CP032698_70	70.1|5488566|21|CP032698|PILER-CR	5488566-5488586	21	CP032698.1	2483036-2483056	2	0.905
CP032698_70	70.1|5488566|21|CP032698|PILER-CR	5488566-5488586	21	CP032698.1	4648964-4648984	2	0.905
CP032698_70	70.1|5488566|21|CP032698|PILER-CR	5488566-5488586	21	CP032698.1	6295052-6295072	2	0.905
CP032698_70	70.1|5488566|21|CP032698|PILER-CR	5488566-5488586	21	CP032698.1	6364927-6364947	2	0.905
CP032698_70	70.1|5488566|21|CP032698|PILER-CR	5488566-5488586	21	CP032698.1	6903042-6903062	2	0.905
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	1230386-1230417	2	0.938
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	3568051-3568082	2	0.938
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	3568397-3568428	2	0.938
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	3892462-3892493	2	0.938
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	3983465-3983496	2	0.938
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	3992569-3992600	2	0.938
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	4801239-4801270	2	0.938
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	5445761-5445792	2	0.938
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	5936536-5936567	2	0.938
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	CP032698.1	6475136-6475167	2	0.938
CP032698_71	71.1|5489850|34|CP032698|CRT	5489850-5489883	34	CP032698.1	5764006-5764039	2	0.941
CP032698_71	71.2|5489906|37|CP032698|CRT	5489906-5489942	37	CP032698.1	1822045-1822081	2	0.946
CP032698_71	71.2|5489906|37|CP032698|CRT	5489906-5489942	37	CP032698.1	3362169-3362205	2	0.946
CP032698_71	71.2|5489906|37|CP032698|CRT	5489906-5489942	37	CP032698.1	5420262-5420298	2	0.946
CP032698_71	71.3|5489965|34|CP032698|CRT	5489965-5489998	34	CP032698.1	4801236-4801269	2	0.941
CP032698_71	71.4|5490021|36|CP032698|CRT	5490021-5490056	36	CP032698.1	2624387-2624422	2	0.944
CP032698_71	71.4|5490021|36|CP032698|CRT	5490021-5490056	36	CP032698.1	4008398-4008433	2	0.944
CP032698_72	72.1|5500919|37|CP032698|CRISPRCasFinder	5500919-5500955	37	CP032698.1	1230325-1230361	2	0.946
CP032698_72	72.1|5500919|37|CP032698|CRISPRCasFinder	5500919-5500955	37	CP032698.1	3467241-3467277	2	0.946
CP032698_72	72.1|5500919|37|CP032698|CRISPRCasFinder	5500919-5500955	37	CP032698.1	5862101-5862137	2	0.946
CP032698_74	74.1|5520262|49|CP032698|CRISPRCasFinder	5520262-5520310	49	CP032698.1	7389980-7390028	2	0.959
CP032698_77	77.2|5941644|31|CP032698|PILER-CR	5941644-5941674	31	CP032698.1	1821936-1821966	2	0.935
CP032698_77	77.3|5941700|32|CP032698|PILER-CR	5941700-5941731	32	CP032698.1	1821991-1822022	2	0.938
CP032698_79	79.1|6011567|33|CP032698|PILER-CR	6011567-6011599	33	CP032698.1	3992566-3992598	2	0.939
CP032698_79	79.1|6011567|33|CP032698|PILER-CR	6011567-6011599	33	CP032698.1	5764007-5764039	2	0.939
CP032698_79	79.1|6011567|33|CP032698|PILER-CR	6011567-6011599	33	CP032698.1	5936533-5936565	2	0.939
CP032698_79	79.2|6011623|37|CP032698|PILER-CR	6011623-6011659	37	CP032698.1	6394820-6394856	2	0.946
CP032698_79	79.3|6011683|32|CP032698|PILER-CR	6011683-6011714	32	CP032698.1	3570221-3570252	2	0.938
CP032698_84	84.1|6088620|47|CP032698|CRISPRCasFinder	6088620-6088666	47	CP032698.1	4480485-4480531	2	0.957
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	3568282-3568312	2	0.935
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	3892462-3892492	2	0.935
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	4967521-4967551	2	0.935
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	5788926-5788956	2	0.935
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	5847496-5847526	2	0.935
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	CP032698.1	5853557-5853587	2	0.935
CP032698_85	85.3|6253254|36|CP032698|CRT	6253254-6253289	36	CP032698.1	3795488-3795523	2	0.944
CP032698_85	85.3|6253254|36|CP032698|CRT	6253254-6253289	36	CP032698.1	3795549-3795584	2	0.944
CP032698_85	85.3|6253254|36|CP032698|CRT	6253254-6253289	36	CP032698.1	3795610-3795645	2	0.944
CP032698_85	85.3|6253254|36|CP032698|CRT	6253254-6253289	36	CP032698.1	3795671-3795706	2	0.944
CP032698_85	85.3|6253254|36|CP032698|CRT	6253254-6253289	36	CP032698.1	3795732-3795767	2	0.944
CP032698_85	85.3|6253254|36|CP032698|CRT	6253254-6253289	36	CP032698.1	3795793-3795828	2	0.944
CP032698_85	85.3|6253254|36|CP032698|CRT	6253254-6253289	36	CP032698.1	3795854-3795889	2	0.944
CP032698_85	85.3|6253254|36|CP032698|CRT	6253254-6253289	36	CP032698.1	3795915-3795950	2	0.944
CP032698_85	85.3|6253254|36|CP032698|CRT	6253254-6253289	36	CP032698.1	4189880-4189915	2	0.944
CP032698_85	85.3|6253254|36|CP032698|CRT	6253254-6253289	36	CP032698.1	4422483-4422518	2	0.944
CP032698_85	85.4|6253315|31|CP032698|CRT	6253315-6253345	31	CP032698.1	1693781-1693811	2	0.935
CP032698_85	85.4|6253315|31|CP032698|CRT	6253315-6253345	31	CP032698.1	2482967-2482997	2	0.935
CP032698_85	85.4|6253315|31|CP032698|CRT	6253315-6253345	31	CP032698.1	2483082-2483112	2	0.935
CP032698_88	88.1|6739104|47|CP032698|CRISPRCasFinder	6739104-6739150	47	CP032698.1	3662458-3662504	2	0.957
CP032698_89	89.2|6739334|35|CP032698|CRT	6739334-6739368	35	CP032698.1	2474829-2474863	2	0.943
CP032698_89	89.2|6739334|35|CP032698|CRT	6739334-6739368	35	CP032698.1	3282387-3282421	2	0.943
CP032698_89	89.4|6739450|35|CP032698|CRT	6739450-6739484	35	CP032698.1	2474829-2474863	2	0.943
CP032698_89	89.4|6739450|35|CP032698|CRT	6739450-6739484	35	CP032698.1	3282387-3282421	2	0.943
CP032698_90	90.1|6763447|31|CP032698|CRISPRCasFinder	6763447-6763477	31	CP032698.1	3568168-3568198	2	0.935
CP032698_90	90.1|6763447|31|CP032698|CRISPRCasFinder	6763447-6763477	31	CP032698.1	3919348-3919378	2	0.935
CP032698_90	90.1|6763447|31|CP032698|CRISPRCasFinder	6763447-6763477	31	CP032698.1	4787739-4787769	2	0.935
CP032698_90	90.1|6763447|31|CP032698|CRISPRCasFinder	6763447-6763477	31	CP032698.1	4787854-4787884	2	0.935
CP032698_90	90.1|6763447|31|CP032698|CRISPRCasFinder	6763447-6763477	31	CP032698.1	5853440-5853470	2	0.935
CP032698_91	91.1|6963306|34|CP032698|CRISPRCasFinder	6963306-6963339	34	CP032698.1	1230385-1230418	2	0.941
CP032698_95	95.1|7390256|34|CP032698|PILER-CR	7390256-7390289	34	CP032698.1	5306813-5306846	2	0.941
CP032698_95	95.1|7390256|34|CP032698|PILER-CR	7390256-7390289	34	CP032698.1	7574124-7574157	2	0.941
CP032698_95	95.3|7390372|34|CP032698|PILER-CR	7390372-7390405	34	CP032698.1	1693722-1693755	2	0.941
CP032698_95	95.3|7390372|34|CP032698|PILER-CR	7390372-7390405	34	CP032698.1	4967576-4967609	2	0.941
CP032698_95	95.3|7390372|34|CP032698|PILER-CR	7390372-7390405	34	CP032698.1	5090838-5090871	2	0.941
CP032698_95	95.3|7390372|34|CP032698|PILER-CR	7390372-7390405	34	CP032698.1	5445818-5445851	2	0.941
CP032698_95	95.7|7390372|37|CP032698|CRT	7390372-7390408	37	CP032698.1	5445818-5445854	2	0.946
CP032698_96	96.1|7574011|33|CP032698|CRISPRCasFinder	7574011-7574043	33	CP032698.1	6642003-6642035	2	0.939
CP032698_96	96.2|7574068|32|CP032698|CRISPRCasFinder	7574068-7574099	32	CP032698.1	5326274-5326305	2	0.938
CP032698_96	96.2|7574068|32|CP032698|CRISPRCasFinder	7574068-7574099	32	CP032698.1	5326331-5326362	2	0.938
CP032698_96	96.2|7574068|32|CP032698|CRISPRCasFinder	7574068-7574099	32	CP032698.1	5326388-5326419	2	0.938
CP032698_96	96.2|7574068|32|CP032698|CRISPRCasFinder	7574068-7574099	32	CP032698.1	5326445-5326476	2	0.938

1. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 4648745-4648764, mismatch: 0, identity: 1.0

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccccgacccgcac	Protospacer
********************

2. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 4008401-4008434, mismatch: 0, identity: 1.0

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcgtctgcgggccgcaggtggc	Protospacer
**********************************

3. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 3568167-3568195, mismatch: 0, identity: 1.0

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgaccctgcggaccgtgcccgctt	Protospacer
*****************************

4. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 3919351-3919379, mismatch: 0, identity: 1.0

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgaccctgcggaccgtgcccgctt	Protospacer
*****************************

5. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 4787738-4787766, mismatch: 0, identity: 1.0

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgaccctgcggaccgtgcccgctt	Protospacer
*****************************

6. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 4787853-4787881, mismatch: 0, identity: 1.0

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgaccctgcggaccgtgcccgctt	Protospacer
*****************************

7. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 5853443-5853471, mismatch: 0, identity: 1.0

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgaccctgcggaccgtgcccgctt	Protospacer
*****************************

8. spacer 34.9|4014032|20|CP032698|PILER-CR matches to position: 4147550-4147569, mismatch: 0, identity: 1.0

acccctctcgatcccgcgga	CRISPR spacer
acccctctcgatcccgcgga	Protospacer
********************

9. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 5038006-5038035, mismatch: 0, identity: 1.0

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gacgcgggcacggtccgcaggatcgagagg	Protospacer
******************************

10. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 5038001-5038031, mismatch: 0, identity: 1.0

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcaggatcgagaggggtta	Protospacer
*******************************

11. spacer 47.1|4480725|33|CP032698|PILER-CR,CRT matches to position: 5406186-5406218, mismatch: 0, identity: 1.0

cccagccacgcacgacccgcagacgaaaacggg	CRISPR spacer
cccagccacgcacgacccgcagacgaaaacggg	Protospacer
*********************************

12. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 3568282-3568312, mismatch: 0, identity: 1.0

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtgcccgcttc	Protospacer
*******************************

13. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 5788926-5788956, mismatch: 0, identity: 1.0

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtgcccgcttc	Protospacer
*******************************

14. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 5853557-5853587, mismatch: 0, identity: 1.0

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtgcccgcttc	Protospacer
*******************************

15. spacer 59.1|5075217|32|CP032698|CRISPRCasFinder matches to position: 4801238-4801269, mismatch: 0, identity: 1.0

gaagcgaccacgacccgcaggatcgagagggt	CRISPR spacer
gaagcgaccacgacccgcaggatcgagagggt	Protospacer
********************************

16. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 5862102-5862136, mismatch: 0, identity: 1.0

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggtccgcagccgaaaacgggttt	Protospacer
***********************************

17. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to position: 3983463-3983493, mismatch: 0, identity: 1.0

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
aaccccctcgatcctgcgggccgtggtcgct	Protospacer
*******************************

18. spacer 70.1|5488566|21|CP032698|PILER-CR matches to position: 5821764-5821784, mismatch: 0, identity: 1.0

acccgcagacgaaaacgggtt	CRISPR spacer
acccgcagacgaaaacgggtt	Protospacer
*********************

19. spacer 79.3|6011683|32|CP032698|PILER-CR matches to position: 3550412-3550443, mismatch: 0, identity: 1.0

ggcaggactggtgccggcccggacgggacttg	CRISPR spacer
ggcaggactggtgccggcccggacgggacttg	Protospacer
********************************

20. spacer 82.1|6018962|55|CP032698|CRISPRCasFinder matches to position: 4189655-4189709, mismatch: 0, identity: 1.0

aggcccgggccatccaaccctgcgcctacgggcgggtgggtggggaaggtgcctt	CRISPR spacer
aggcccgggccatccaaccctgcgcctacgggcgggtgggtggggaaggtgcctt	Protospacer
*******************************************************

21. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to position: 3568166-3568197, mismatch: 1, identity: 0.969

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
gaagcgggcacggtccgcagggtcgagagggt	Protospacer
** *****************************

22. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to position: 3919349-3919380, mismatch: 1, identity: 0.969

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
gaagcgggcacggtccgcagggtcgagagggt	Protospacer
** *****************************

23. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to position: 4787737-4787768, mismatch: 1, identity: 0.969

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
gaagcgggcacggtccgcagggtcgagagggt	Protospacer
** *****************************

24. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to position: 4787852-4787883, mismatch: 1, identity: 0.969

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
gaagcgggcacggtccgcagggtcgagagggt	Protospacer
** *****************************

25. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to position: 5853441-5853472, mismatch: 1, identity: 0.969

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
gaagcgggcacggtccgcagggtcgagagggt	Protospacer
** *****************************

26. spacer 5.1|1822206|50|CP032698|CRISPRCasFinder matches to position: 4189657-4189706, mismatch: 1, identity: 0.98

cccgggccatccaaccctgcgcctacgggcgggtgggtgggtaaggtgcc	CRISPR spacer
cccgggccatccaaccctgcgcctacgggcgggtgggtggggaaggtgcc	Protospacer
***************************************** ********

27. spacer 8.1|2471199|28|CP032698|CRISPRCasFinder matches to position: 4502923-4502950, mismatch: 1, identity: 0.964

ccacggcccgcagacgaaaacgggtttg	CRISPR spacer
ccacggcccgcagacgaagacgggtttg	Protospacer
******************.*********

28. spacer 8.1|2471199|28|CP032698|CRISPRCasFinder matches to position: 5633102-5633129, mismatch: 1, identity: 0.964

ccacggcccgcagacgaaaacgggtttg	CRISPR spacer
ccgcggcccgcagacgaaaacgggtttg	Protospacer
**.*************************

29. spacer 12.1|2818688|32|CP032698|CRISPRCasFinder matches to position: 5514204-5514235, mismatch: 1, identity: 0.969

gaagcgagcacggtccgcagaccgaagggcct	CRISPR spacer
gaagcgaccacggtccgcagaccgaagggcct	Protospacer
******* ************************

30. spacer 12.1|2818688|32|CP032698|CRISPRCasFinder matches to position: 6319299-6319330, mismatch: 1, identity: 0.969

gaagcgagcacggtccgcagaccgaagggcct	CRISPR spacer
gaagcgggcacggtccgcagaccgaagggcct	Protospacer
******.*************************

31. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 3092489-3092508, mismatch: 1, identity: 0.95

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccacgacccgcac	Protospacer
********* **********

32. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 3092590-3092609, mismatch: 1, identity: 0.95

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccacgacccgcac	Protospacer
********* **********

33. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 6182534-6182553, mismatch: 1, identity: 0.95

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccacgacccgcac	Protospacer
********* **********

34. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3550353-3550386, mismatch: 1, identity: 0.971

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcggctgcgggccgcaggtggc	Protospacer
*************** ******************

35. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3756059-3756092, mismatch: 1, identity: 0.971

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgtcttcgtctgcgggccgcaggtggc	Protospacer
**********.***********************

36. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 5853380-5853413, mismatch: 1, identity: 0.971

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaccccgttttcgtctgcgggccgcaggtggc	Protospacer
**** *****************************

37. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 6475245-6475278, mismatch: 1, identity: 0.971

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcggctgcgggccgcaggtggc	Protospacer
*************** ******************

38. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 7052559-7052592, mismatch: 1, identity: 0.971

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcgcctgcgggccgcaggtggc	Protospacer
***************.******************

39. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 3568454-3568489, mismatch: 1, identity: 0.972

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccgcggcccgcagacgaaaacgggtttt	Protospacer
************************** *********

40. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 3444539-3444567, mismatch: 1, identity: 0.966

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgatcctgcggaccgtgcccgctt	Protospacer
********.********************

41. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 3568283-3568311, mismatch: 1, identity: 0.966

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgatcctgcggaccgtgcccgctt	Protospacer
********.********************

42. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 3892463-3892491, mismatch: 1, identity: 0.966

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgaccctgcggaccgtgctcgctt	Protospacer
***********************.*****

43. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 5788927-5788955, mismatch: 1, identity: 0.966

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgatcctgcggaccgtgcccgctt	Protospacer
********.********************

44. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 5853558-5853586, mismatch: 1, identity: 0.966

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgatcctgcggaccgtgcccgctt	Protospacer
********.********************

45. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 1693722-1693754, mismatch: 1, identity: 0.97

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggt	Protospacer
***************************.*****

46. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 4787793-4787825, mismatch: 1, identity: 0.97

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacggcccgcaggcgaaagcgggt	Protospacer
********************* ***********

47. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 4787908-4787940, mismatch: 1, identity: 0.97

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacggcccgcaggcgaaagcgggt	Protospacer
********************* ***********

48. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 4801181-4801213, mismatch: 1, identity: 0.97

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacccacggcccgcagccgaaagcgggt	Protospacer
******** ************************

49. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 4967577-4967609, mismatch: 1, identity: 0.97

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggt	Protospacer
***************************.*****

50. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 5445818-5445850, mismatch: 1, identity: 0.97

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggt	Protospacer
***************************.*****

51. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 2616828-2616847, mismatch: 1, identity: 0.95

aacccgccttcgtccgcggg	CRISPR spacer
aacccgtcttcgtccgcggg	Protospacer
******.*************

52. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 3157085-3157104, mismatch: 1, identity: 0.95

aacccgccttcgtccgcggg	CRISPR spacer
aacccgccttcgtccgcagg	Protospacer
*****************.**

53. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 4916369-4916388, mismatch: 1, identity: 0.95

aacccgccttcgtccgcggg	CRISPR spacer
aacccgtcttcgtccgcggg	Protospacer
******.*************

54. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 5847553-5847572, mismatch: 1, identity: 0.95

aacccgccttcgtccgcggg	CRISPR spacer
aacccgctttcgtccgcggg	Protospacer
*******.************

55. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 6903042-6903061, mismatch: 1, identity: 0.95

aacccgccttcgtccgcggg	CRISPR spacer
aacccgctttcgtccgcggg	Protospacer
*******.************

56. spacer 34.4|4013847|36|CP032698|CRT matches to position: 3585769-3585804, mismatch: 1, identity: 0.972

aaaaccctcggtcacgtgcggaccgtgctcgcttct	CRISPR spacer
aaaaccctcggtcacgtgcggaccgtgcccgcttct	Protospacer
****************************.*******

57. spacer 34.4|4013847|36|CP032698|CRT matches to position: 4607070-4607105, mismatch: 1, identity: 0.972

aaaaccctcggtcacgtgcggaccgtgctcgcttct	CRISPR spacer
aaaaccctcggtcatgtgcggaccgtgctcgcttct	Protospacer
**************.*********************

58. spacer 34.4|4013847|36|CP032698|CRT matches to position: 5035086-5035121, mismatch: 1, identity: 0.972

aaaaccctcggtcacgtgcggaccgtgctcgcttct	CRISPR spacer
aaaacccccggtcacgtgcggaccgtgctcgcttct	Protospacer
*******.****************************

59. spacer 34.9|4014032|20|CP032698|PILER-CR matches to position: 5038003-5038022, mismatch: 1, identity: 0.95

acccctctcgatcccgcgga	CRISPR spacer
acccctctcgatcctgcgga	Protospacer
**************.*****

60. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 3550354-3550383, mismatch: 1, identity: 0.967

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acctgcggcccgcagccgaaaacgggtttt	Protospacer
***.**************************

61. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 3568460-3568489, mismatch: 1, identity: 0.967

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccgcggcccgcagacgaaaacgggtttt	Protospacer
*************** **************

62. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 6475246-6475275, mismatch: 1, identity: 0.967

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acctgcggcccgcagccgaaaacgggtttt	Protospacer
***.**************************

63. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 3585726-3585753, mismatch: 1, identity: 0.964

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcagggtcgagaggggtt	Protospacer
*************** ************

64. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 4967518-4967545, mismatch: 1, identity: 0.964

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcagattcgagaggggtt	Protospacer
**************.*************

65. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 5038002-5038029, mismatch: 1, identity: 0.964

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcaggatcgagaggggtt	Protospacer
*************** ************

66. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 3568282-3568311, mismatch: 1, identity: 0.967

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgggcacggtccgcaggatcgagagg	Protospacer
** ***************************

67. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 5788927-5788956, mismatch: 1, identity: 0.967

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgggcacggtccgcaggatcgagagg	Protospacer
** ***************************

68. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 5847497-5847526, mismatch: 1, identity: 0.967

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gacgcgggcacggtccgcagaatcgagagg	Protospacer
********************.*********

69. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 5853558-5853587, mismatch: 1, identity: 0.967

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgggcacggtccgcaggatcgagagg	Protospacer
** ***************************

70. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 3568286-3568316, mismatch: 1, identity: 0.968

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcaggatcgagagggttta	Protospacer
*************************** ***

71. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 5788922-5788952, mismatch: 1, identity: 0.968

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcaggatcgagagggttta	Protospacer
*************************** ***

72. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 5847492-5847522, mismatch: 1, identity: 0.968

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcagaatcgagaggggtta	Protospacer
****************.**************

73. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 5853553-5853583, mismatch: 1, identity: 0.968

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcaggatcgagagggttta	Protospacer
*************************** ***

74. spacer 42.1|4174644|38|CP032698|CRT matches to position: 4008396-4008433, mismatch: 1, identity: 0.974

gaccagccacctgcggcccgcagacgaaaacggttttt	CRISPR spacer
gaccagccacctgcggcccgcagacgaaaacgggtttt	Protospacer
********************************* ****

75. spacer 43.1|4204779|53|CP032698|CRISPRCasFinder matches to position: 4480558-4480610, mismatch: 1, identity: 0.981

aggcccgggccatccaaccctgcgcctacgggcgggcgggtgggaaaacgcgt	CRISPR spacer
aggcccgggccatccaaccctgcgcctacgggcgggcgggtgggcaaacgcgt	Protospacer
******************************************** ********

76. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 3568283-3568315, mismatch: 1, identity: 0.97

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgatcctgcggaccgtgcccgctt	Protospacer
******.**************************

77. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 4603250-4603282, mismatch: 1, identity: 0.97

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccccctcgatcctgcggaccgtgctcgctt	Protospacer
***************************.*****

78. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 5788923-5788955, mismatch: 1, identity: 0.97

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgatcctgcggaccgtgcccgctt	Protospacer
******.**************************

79. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 5853554-5853586, mismatch: 1, identity: 0.97

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgatcctgcggaccgtgcccgctt	Protospacer
******.**************************

80. spacer 47.1|4480725|33|CP032698|PILER-CR,CRT matches to position: 5627692-5627724, mismatch: 1, identity: 0.97

cccagccacgcacgacccgcagacgaaaacggg	CRISPR spacer
cccagccacgcacgacccgcagccgaaaacggg	Protospacer
********************** **********

81. spacer 47.1|4480725|33|CP032698|PILER-CR,CRT matches to position: 5821766-5821798, mismatch: 1, identity: 0.97

cccagccacgcacgacccgcagacgaaaacggg	CRISPR spacer
cccagccacacacgacccgcagacgaaaacggg	Protospacer
*********.***********************

82. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 3568165-3568196, mismatch: 1, identity: 0.969

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcagggtcgagaggg	Protospacer
********************** *********

83. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 3568281-3568312, mismatch: 1, identity: 0.969

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcaggatcgagaggg	Protospacer
********************** *********

84. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 3919350-3919381, mismatch: 1, identity: 0.969

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcagggtcgagaggg	Protospacer
********************** *********

85. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 4776924-4776955, mismatch: 1, identity: 0.969

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgagcacggtccgcaggttcgagaggg	Protospacer
*******.************************

86. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 4787736-4787767, mismatch: 1, identity: 0.969

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcagggtcgagaggg	Protospacer
********************** *********

87. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 4787851-4787882, mismatch: 1, identity: 0.969

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcagggtcgagaggg	Protospacer
********************** *********

88. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 5788926-5788957, mismatch: 1, identity: 0.969

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcaggatcgagaggg	Protospacer
********************** *********

89. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 5853442-5853473, mismatch: 1, identity: 0.969

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcagggtcgagaggg	Protospacer
********************** *********

90. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 5853557-5853588, mismatch: 1, identity: 0.969

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcaggatcgagaggg	Protospacer
********************** *********

91. spacer 47.3|4480838|36|CP032698|PILER-CR,CRT matches to position: 4422484-4422519, mismatch: 1, identity: 0.972

cccagccacgcacggcccgcagacgaaaacgggttt	CRISPR spacer
cccagccacccacggcccgcagacgaaaacgggttt	Protospacer
********* **************************

92. spacer 47.3|4480838|36|CP032698|PILER-CR,CRT matches to position: 5090837-5090872, mismatch: 1, identity: 0.972

cccagccacgcacggcccgcagacgaaaacgggttt	CRISPR spacer
cccagccacgcacggctcgcagacgaaaacgggttt	Protospacer
****************.*******************

93. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 1978514-1978534, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

94. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 2474772-2474792, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

95. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 2936131-2936151, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggcccgcag	Protospacer
******** ************

96. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3362388-3362408, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggcccgcag	Protospacer
******** ************

97. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3362538-3362558, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggcccgcag	Protospacer
******** ************

98. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3795488-3795508, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

99. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3795549-3795569, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

100. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3795610-3795630, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

101. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3795671-3795691, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

102. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3795732-3795752, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

103. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3795793-3795813, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

104. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3795854-3795874, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

105. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3795915-3795935, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

106. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3911154-3911174, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

107. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3911213-3911233, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

108. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3926214-3926234, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggcccgcag	Protospacer
******** ************

109. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4189880-4189900, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

110. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4189938-4189958, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

111. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4204611-4204631, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggcccgcag	Protospacer
******** ************

112. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4422498-4422518, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

113. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4472221-4472241, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

114. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4502915-4502935, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

115. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4801193-4801213, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

116. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4912526-4912546, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

117. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5936490-5936510, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

118. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5936605-5936625, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

119. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6182593-6182613, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

120. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6394837-6394857, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

121. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6519300-6519320, mismatch: 1, identity: 0.952

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggcccgcag	Protospacer
****** **************

122. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 3157232-3157262, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtgctcgcttc	Protospacer
************************.******

123. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 3568166-3568196, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgaccctgcggaccgtgcccgcttc	Protospacer
*********.*********************

124. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 3919350-3919380, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgaccctgcggaccgtgcccgcttc	Protospacer
*********.*********************

125. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 4189824-4189854, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtgctcgcttc	Protospacer
************************.******

126. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 4787737-4787767, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgaccctgcggaccgtgcccgcttc	Protospacer
*********.*********************

127. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 4787852-4787882, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgaccctgcggaccgtgcccgcttc	Protospacer
*********.*********************

128. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 5038005-5038035, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtgcccgcgtc	Protospacer
**************************** **

129. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 5763950-5763980, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtgctcgcttc	Protospacer
************************.******

130. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 5853442-5853472, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgaccctgcggaccgtgcccgcttc	Protospacer
*********.*********************

131. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 6364975-6365005, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtgctcgcttc	Protospacer
************************.******

132. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 6394767-6394797, mismatch: 1, identity: 0.968

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtgctcgcttc	Protospacer
************************.******

133. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 3795443-3795466, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

134. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 3795504-3795527, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

135. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 3795565-3795588, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

136. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 3795626-3795649, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

137. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 3795687-3795710, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

138. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 3795748-3795771, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

139. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 3795809-3795832, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

140. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 3795870-3795893, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

141. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 3795931-3795954, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

142. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 4008414-4008437, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

143. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 5420278-5420301, mismatch: 1, identity: 0.958

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcgtctgcg	Protospacer
*************.**********

144. spacer 55.3|4866586|37|CP032698|PILER-CR matches to position: 3838628-3838664, mismatch: 1, identity: 0.973

agaagcgagcacggtccgcacgtgaccgggggttttg	CRISPR spacer
agaagcgagcacggtccgcacatgaccgggggttttg	Protospacer
*********************.***************

145. spacer 56.1|4878703|37|CP032698|CRT matches to position: 4502972-4503008, mismatch: 1, identity: 0.973

gaagcgggcacggtccgcacacgacagcgggttttca	CRISPR spacer
gaagcgagcacggtccgcacacgacagcgggttttca	Protospacer
******.******************************

146. spacer 58.1|5049170|37|CP032698|PILER-CR,CRT matches to position: 1693722-1693758, mismatch: 1, identity: 0.973

ccagccacgcacggcccgcagtcgaaaacgggtttcc	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggtttcc	Protospacer
*********************.***************

147. spacer 58.1|5049170|37|CP032698|PILER-CR,CRT matches to position: 3568222-3568258, mismatch: 1, identity: 0.973

ccagccacgcacggcccgcagtcgaaaacgggtttcc	CRISPR spacer
ccagccacgcacggcccgcagacgaaaacgggtttcc	Protospacer
********************* ***************

148. spacer 58.1|5049170|37|CP032698|PILER-CR,CRT matches to position: 5853610-5853646, mismatch: 1, identity: 0.973

ccagccacgcacggcccgcagtcgaaaacgggtttcc	CRISPR spacer
ccagccacgcacggtccgcagtcgaaaacgggtttcc	Protospacer
**************.**********************

149. spacer 59.1|5075217|32|CP032698|CRISPRCasFinder matches to position: 5764006-5764037, mismatch: 1, identity: 0.969

gaagcgaccacgacccgcaggatcgagagggt	CRISPR spacer
gaagcgaccacggcccgcaggatcgagagggt	Protospacer
************.*******************

150. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 1693722-1693756, mismatch: 1, identity: 0.971

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggttt	Protospacer
**************.********************

151. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 3818733-3818767, mismatch: 1, identity: 0.971

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggtccgcagacgaaaacgggttt	Protospacer
********************* *************

152. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 4136293-4136327, mismatch: 1, identity: 0.971

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacccacggtccgcagccgaaaacgggttt	Protospacer
******** **************************

153. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 4967575-4967609, mismatch: 1, identity: 0.971

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggttt	Protospacer
**************.********************

154. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 5445818-5445852, mismatch: 1, identity: 0.971

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggttt	Protospacer
**************.********************

155. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 5488665-5488699, mismatch: 1, identity: 0.971

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggtccgcagtcgaaaacgggttt	Protospacer
*********************.*************

156. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 5853612-5853646, mismatch: 1, identity: 0.971

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggtccgcagtcgaaaacgggttt	Protospacer
*********************.*************

157. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 3838632-3838663, mismatch: 1, identity: 0.969

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gaagcgagcacggtccgcacatgaccgggggt	Protospacer
******.*************************

158. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 6088934-6088965, mismatch: 1, identity: 0.969

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gaagcgggcacggtctgcacatgaccgggggt	Protospacer
***************.****************

159. spacer 62.5|5196207|33|CP032698|CRT matches to position: 5633160-5633192, mismatch: 1, identity: 0.97

acctgctccgtccgggcccgcaccggttctgcc	CRISPR spacer
acctgccccgtccgggcccgcaccggttctgcc	Protospacer
******.**************************

160. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to position: 5764008-5764038, mismatch: 1, identity: 0.968

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
aaccctctcgatcctgcgggccgtggtcgct	Protospacer
*****.*************************

161. spacer 70.1|5488566|21|CP032698|PILER-CR matches to position: 3795379-3795399, mismatch: 1, identity: 0.952

acccgcagacgaaaacgggtt	CRISPR spacer
accggcagacgaaaacgggtt	Protospacer
*** *****************

162. spacer 70.1|5488566|21|CP032698|PILER-CR matches to position: 4020197-4020217, mismatch: 1, identity: 0.952

acccgcagacgaaaacgggtt	CRISPR spacer
acccgcagacgaaagcgggtt	Protospacer
**************.******

163. spacer 70.1|5488566|21|CP032698|PILER-CR matches to position: 5789016-5789036, mismatch: 1, identity: 0.952

acccgcagacgaaaacgggtt	CRISPR spacer
acccgcagccgaaaacgggtt	Protospacer
******** ************

164. spacer 70.1|5488566|21|CP032698|PILER-CR matches to position: 5964751-5964771, mismatch: 1, identity: 0.952

acccgcagacgaaaacgggtt	CRISPR spacer
acccgcggacgaaaacgggtt	Protospacer
******.**************

165. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 5764005-5764036, mismatch: 1, identity: 0.969

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgaccacggcccgcaggatcgagaggg	Protospacer
**********************.*********

166. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 6295097-6295128, mismatch: 1, identity: 0.969

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgaccacggtccgcagggtcgagaggg	Protospacer
**************.*****************

167. spacer 77.2|5941644|31|CP032698|PILER-CR matches to position: 4776867-4776897, mismatch: 1, identity: 0.968

cccccggtcatgtgcgggccgtggtcgtttt	CRISPR spacer
cccccggtcatgtgcgggccgtggtcgcttt	Protospacer
***************************.***

168. spacer 79.1|6011567|33|CP032698|PILER-CR matches to position: 1978573-1978605, mismatch: 1, identity: 0.97

aaaccctcccgaacctgcgggccgtggtcgctt	CRISPR spacer
aaaccctctcgaacctgcgggccgtggtcgctt	Protospacer
********.************************

169. spacer 79.2|6011623|37|CP032698|PILER-CR matches to position: 3675756-3675792, mismatch: 1, identity: 0.973

aagaaacccgttttcgtctgcgggccgtacgtggctg	CRISPR spacer
aagaaacccgttttcgtctgcgggccgtacggggctg	Protospacer
******************************* *****

170. spacer 85.2|6253198|31|CP032698|CRT matches to position: 3568166-3568196, mismatch: 1, identity: 0.968

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgaccctgcggaccgtgcccgcttc	Protospacer
**************************** **

171. spacer 85.2|6253198|31|CP032698|CRT matches to position: 3919350-3919380, mismatch: 1, identity: 0.968

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgaccctgcggaccgtgcccgcttc	Protospacer
**************************** **

172. spacer 85.2|6253198|31|CP032698|CRT matches to position: 4787737-4787767, mismatch: 1, identity: 0.968

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgaccctgcggaccgtgcccgcttc	Protospacer
**************************** **

173. spacer 85.2|6253198|31|CP032698|CRT matches to position: 4787852-4787882, mismatch: 1, identity: 0.968

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgaccctgcggaccgtgcccgcttc	Protospacer
**************************** **

174. spacer 85.2|6253198|31|CP032698|CRT matches to position: 5038005-5038035, mismatch: 1, identity: 0.968

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgatcctgcggaccgtgcccgcgtc	Protospacer
*********.*********************

175. spacer 85.2|6253198|31|CP032698|CRT matches to position: 5853442-5853472, mismatch: 1, identity: 0.968

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgaccctgcggaccgtgcccgcttc	Protospacer
**************************** **

176. spacer 85.4|6253315|31|CP032698|CRT matches to position: 3366364-3366394, mismatch: 1, identity: 0.968

agcccttcggtctgcggaccgtgctcgcttc	CRISPR spacer
agcccttcggtctgcgggccgtgctcgcttc	Protospacer
*****************.*************

177. spacer 85.4|6253315|31|CP032698|CRT matches to position: 3919465-3919495, mismatch: 1, identity: 0.968

agcccttcggtctgcggaccgtgctcgcttc	CRISPR spacer
agcccttcggtctgcggaccgtggtcgcttc	Protospacer
*********************** *******

178. spacer 85.4|6253315|31|CP032698|CRT matches to position: 5831472-5831502, mismatch: 1, identity: 0.968

agcccttcggtctgcggaccgtgctcgcttc	CRISPR spacer
agcccttcggtctgcggaccgtggtcgcttc	Protospacer
*********************** *******

179. spacer 89.2|6739334|35|CP032698|CRT matches to position: 3282330-3282364, mismatch: 1, identity: 0.971

gaagcgaccacggcccgcaggccgagagcggggtt	CRISPR spacer
gaagcgaccacggcccgcaggccgagagcgggttt	Protospacer
******************************** **

180. spacer 89.4|6739450|35|CP032698|CRT matches to position: 3282330-3282364, mismatch: 1, identity: 0.971

gaagcgaccacggcccgcaggccgagagcggggtt	CRISPR spacer
gaagcgaccacggcccgcaggccgagagcgggttt	Protospacer
******************************** **

181. spacer 94.2|7161791|17|CP032698|PILER-CR matches to position: 1969192-1969208, mismatch: 1, identity: 0.941

gcacggtggagggggtg	CRISPR spacer
gcacggtggagcgggtg	Protospacer
*********** *****

182. spacer 97.1|7776827|17|CP032698|CRISPRCasFinder matches to position: 1932097-1932113, mismatch: 1, identity: 0.941

gccaagccccgcccgcc	CRISPR spacer
gccgagccccgcccgcc	Protospacer
***.*************

183. spacer 97.1|7776827|17|CP032698|CRISPRCasFinder matches to position: 2471280-2471296, mismatch: 1, identity: 0.941

gccaagccccgcccgcc	CRISPR spacer
gccaagccccccccgcc	Protospacer
********** ******

184. spacer 2.1|1292446|22|CP032698|PILER-CR matches to position: 2474886-2474907, mismatch: 2, identity: 0.909

ccagccacctgcggcgtgcaga	CRISPR spacer
ccagccacctgcggcccgcaga	Protospacer
*************** .*****

185. spacer 2.1|1292446|22|CP032698|PILER-CR matches to position: 2967202-2967223, mismatch: 2, identity: 0.909

ccagccacctgcggcgtgcaga	CRISPR spacer
ccagccacctgcggcccgcaga	Protospacer
*************** .*****

186. spacer 2.1|1292446|22|CP032698|PILER-CR matches to position: 2967284-2967305, mismatch: 2, identity: 0.909

ccagccacctgcggcgtgcaga	CRISPR spacer
ccagccacctgcggcccgcaga	Protospacer
*************** .*****

187. spacer 2.1|1292446|22|CP032698|PILER-CR matches to position: 3662319-3662340, mismatch: 2, identity: 0.909

ccagccacctgcggcgtgcaga	CRISPR spacer
ccagccacctgcggcccgcaga	Protospacer
*************** .*****

188. spacer 2.1|1292446|22|CP032698|PILER-CR matches to position: 3756074-3756095, mismatch: 2, identity: 0.909

ccagccacctgcggcgtgcaga	CRISPR spacer
ccagccacctgcggcccgcaga	Protospacer
*************** .*****

189. spacer 2.1|1292446|22|CP032698|PILER-CR matches to position: 3847532-3847553, mismatch: 2, identity: 0.909

ccagccacctgcggcgtgcaga	CRISPR spacer
ccagccacctgcggcccgcaga	Protospacer
*************** .*****

190. spacer 2.1|1292446|22|CP032698|PILER-CR matches to position: 3992522-3992543, mismatch: 2, identity: 0.909

ccagccacctgcggcgtgcaga	CRISPR spacer
ccagccacctgcggcccgcaga	Protospacer
*************** .*****

191. spacer 2.1|1292446|22|CP032698|PILER-CR matches to position: 4008398-4008419, mismatch: 2, identity: 0.909

ccagccacctgcggcgtgcaga	CRISPR spacer
ccagccacctgcggcccgcaga	Protospacer
*************** .*****

192. spacer 2.1|1292446|22|CP032698|PILER-CR matches to position: 5853395-5853416, mismatch: 2, identity: 0.909

ccagccacctgcggcgtgcaga	CRISPR spacer
ccagccacctgcggcccgcaga	Protospacer
*************** .*****

193. spacer 2.3|1292421|35|CP032698|CRISPRCasFinder matches to position: 3662306-3662340, mismatch: 2, identity: 0.943

ccagccacctgcggcgtgcagacgaaaacgggttt	CRISPR spacer
ccagccacctgcggcccgcagacgaaaacgggttt	Protospacer
*************** .******************

194. spacer 2.3|1292421|35|CP032698|CRISPRCasFinder matches to position: 4008398-4008432, mismatch: 2, identity: 0.943

ccagccacctgcggcgtgcagacgaaaacgggttt	CRISPR spacer
ccagccacctgcggcccgcagacgaaaacgggttt	Protospacer
*************** .******************

195. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to position: 3568282-3568313, mismatch: 2, identity: 0.938

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
gaagcgggcacggtccgcaggatcgagagggt	Protospacer
** ******************.**********

196. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to position: 5788925-5788956, mismatch: 2, identity: 0.938

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
gaagcgggcacggtccgcaggatcgagagggt	Protospacer
** ******************.**********

197. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to position: 5853556-5853587, mismatch: 2, identity: 0.938

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
gaagcgggcacggtccgcaggatcgagagggt	Protospacer
** ******************.**********

198. spacer 5.1|1822206|50|CP032698|CRISPRCasFinder matches to position: 2935685-2935734, mismatch: 2, identity: 0.96

cccgggccatccaaccctgcgcctacgggcgggtgggtgggtaaggtgcc	CRISPR spacer
cccgggccatccaaccctgcgcctacgggcgggtgggtgggcgaggtgcc	Protospacer
*****************************************..*******

199. spacer 5.1|1822206|50|CP032698|CRISPRCasFinder matches to position: 3756222-3756271, mismatch: 2, identity: 0.96

cccgggccatccaaccctgcgcctacgggcgggtgggtgggtaaggtgcc	CRISPR spacer
cccgggccatccaaccctgcgcctacgggcgggcgggtggggaaggtgcc	Protospacer
*********************************.******* ********

200. spacer 8.1|2471199|28|CP032698|CRISPRCasFinder matches to position: 5789014-5789041, mismatch: 2, identity: 0.929

ccacggcccgcagacgaaaacgggtttg	CRISPR spacer
ccacgacccgcagccgaaaacgggtttg	Protospacer
*****.******* **************

201. spacer 9.1|2513596|34|CP032698|PILER-CR matches to position: 5503170-5503203, mismatch: 2, identity: 0.941

ccagccacgcacggtgcgaggacgaaaacgggtt	CRISPR spacer
ccagccacgcacggtccgcggacgaaaacgggtt	Protospacer
*************** ** ***************

202. spacer 9.1|2513596|34|CP032698|PILER-CR matches to position: 5514146-5514179, mismatch: 2, identity: 0.941

ccagccacgcacggtgcgaggacgaaaacgggtt	CRISPR spacer
ccagccacgcacggtgcgaggacgaaagggggtt	Protospacer
***************************. *****

203. spacer 12.1|2818688|32|CP032698|CRISPRCasFinder matches to position: 3677591-3677622, mismatch: 2, identity: 0.938

gaagcgagcacggtccgcagaccgaagggcct	CRISPR spacer
gaagcgaccacggtccgcagaccgaagggtct	Protospacer
******* *********************.**

204. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 4916325-4916344, mismatch: 2, identity: 0.9

gaagcgaccccgacccgcac	CRISPR spacer
gacgcgaccacgacccgcac	Protospacer
** ****** **********

205. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 5055052-5055071, mismatch: 2, identity: 0.9

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccacggcccgcac	Protospacer
********* **.*******

206. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 5069742-5069761, mismatch: 2, identity: 0.9

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccacggcccgcac	Protospacer
********* **.*******

207. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 5145799-5145818, mismatch: 2, identity: 0.9

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccacggcccgcac	Protospacer
********* **.*******

208. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 5343067-5343086, mismatch: 2, identity: 0.9

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccacggcccgcac	Protospacer
********* **.*******

209. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 5843946-5843965, mismatch: 2, identity: 0.9

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccacggcccgcac	Protospacer
********* **.*******

210. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 5999429-5999448, mismatch: 2, identity: 0.9

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccgcggcccgcac	Protospacer
********* **.*******

211. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 7161813-7161832, mismatch: 2, identity: 0.9

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgagcacgacccgcac	Protospacer
******* * **********

212. spacer 14.2|2936098|20|CP032698|PILER-CR matches to position: 8306393-8306412, mismatch: 2, identity: 0.9

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccctgacctgcac	Protospacer
**********.****.****

213. spacer 17.1|3328038|48|CP032698|CRISPRCasFinder matches to position: 5145610-5145657, mismatch: 2, identity: 0.958

ctcagcccgttcaacccgccgcacgggcgggtgggtgggcaaacccgc	CRISPR spacer
ctcagcccgttcaacccgccgcacgggtgggcgggtgggcaaacccgc	Protospacer
***************************.***.****************

214. spacer 18.1|3355695|29|CP032698|CRISPRCasFinder matches to position: 3282444-3282472, mismatch: 2, identity: 0.931

ccagccacgcacggtgtgaggccgaaagg	CRISPR spacer
ccagccacgcacggtgcgaggtcgaaagg	Protospacer
****************.****.*******

215. spacer 18.1|3355695|29|CP032698|CRISPRCasFinder matches to position: 5313452-5313480, mismatch: 2, identity: 0.931

ccagccacgcacggtgtgaggccgaaagg	CRISPR spacer
ccagccacgcacggtgcgaggacgaaagg	Protospacer
****************.**** *******

216. spacer 18.1|3355695|29|CP032698|CRISPRCasFinder matches to position: 5514151-5514179, mismatch: 2, identity: 0.931

ccagccacgcacggtgtgaggccgaaagg	CRISPR spacer
ccagccacgcacggtgcgaggacgaaagg	Protospacer
****************.**** *******

217. spacer 18.2|3355751|29|CP032698|CRISPRCasFinder matches to position: 3554478-3554506, mismatch: 2, identity: 0.931

gacgcgggcacggtccgcacacgaaggcg	CRISPR spacer
gacgcgggcacggtccgcggacgaaggcg	Protospacer
******************. *********

218. spacer 18.2|3355751|29|CP032698|CRISPRCasFinder matches to position: 3961638-3961666, mismatch: 2, identity: 0.931

gacgcgggcacggtccgcacacgaaggcg	CRISPR spacer
gacgcgggcacggtccgcacacgacgtcg	Protospacer
************************ * **

219. spacer 18.2|3355751|29|CP032698|CRISPRCasFinder matches to position: 5145970-5145998, mismatch: 2, identity: 0.931

gacgcgggcacggtccgcacacgaaggcg	CRISPR spacer
gaagcgagcacggtccgcacacgaaggcg	Protospacer
** ***.**********************

220. spacer 18.2|3355751|29|CP032698|CRISPRCasFinder matches to position: 5158304-5158332, mismatch: 2, identity: 0.931

gacgcgggcacggtccgcacacgaaggcg	CRISPR spacer
gaagcgagcacggtccgcacacgaaggcg	Protospacer
** ***.**********************

221. spacer 18.2|3355751|29|CP032698|CRISPRCasFinder matches to position: 6365031-6365059, mismatch: 2, identity: 0.931

gacgcgggcacggtccgcacacgaaggcg	CRISPR spacer
gacgcgggcacggtccgcacacgacgtcg	Protospacer
************************ * **

222. spacer 18.2|3355751|29|CP032698|CRISPRCasFinder matches to position: 6786888-6786916, mismatch: 2, identity: 0.931

gacgcgggcacggtccgcacacgaaggcg	CRISPR spacer
gacgcgggcacggtccgcagacgaaagcg	Protospacer
******************* *****.***

223. spacer 18.3|3355706|20|CP032698|PILER-CR matches to position: 3282452-3282471, mismatch: 2, identity: 0.9

gcacggtgtgaggccgaaag	CRISPR spacer
gcacggtgcgaggtcgaaag	Protospacer
********.****.******

224. spacer 18.3|3355706|20|CP032698|PILER-CR matches to position: 5313460-5313479, mismatch: 2, identity: 0.9

gcacggtgtgaggccgaaag	CRISPR spacer
gcacggtgcgaggacgaaag	Protospacer
********.**** ******

225. spacer 18.3|3355706|20|CP032698|PILER-CR matches to position: 5514152-5514171, mismatch: 2, identity: 0.9

gcacggtgtgaggccgaaag	CRISPR spacer
gcacggtgcgaggacgaaag	Protospacer
********.**** ******

226. spacer 18.3|3355706|20|CP032698|PILER-CR matches to position: 5520055-5520074, mismatch: 2, identity: 0.9

gcacggtgtgaggccgaaag	CRISPR spacer
gcacggtgtgaggatgaaag	Protospacer
************* .*****

227. spacer 18.4|3355762|28|CP032698|PILER-CR matches to position: 3554478-3554505, mismatch: 2, identity: 0.929

gacgcgggcacggtccgcacacgaaggc	CRISPR spacer
gacgcgggcacggtccgcggacgaaggc	Protospacer
******************. ********

228. spacer 18.4|3355762|28|CP032698|PILER-CR matches to position: 3832974-3833001, mismatch: 2, identity: 0.929

gacgcgggcacggtccgcacacgaaggc	CRISPR spacer
gacgcgggcacggtccgcaggcgaaggc	Protospacer
******************* .*******

229. spacer 18.4|3355762|28|CP032698|PILER-CR matches to position: 5145970-5145997, mismatch: 2, identity: 0.929

gacgcgggcacggtccgcacacgaaggc	CRISPR spacer
gaagcgagcacggtccgcacacgaaggc	Protospacer
** ***.*********************

230. spacer 18.4|3355762|28|CP032698|PILER-CR matches to position: 5158305-5158332, mismatch: 2, identity: 0.929

gacgcgggcacggtccgcacacgaaggc	CRISPR spacer
gaagcgagcacggtccgcacacgaaggc	Protospacer
** ***.*********************

231. spacer 18.4|3355762|28|CP032698|PILER-CR matches to position: 6786889-6786916, mismatch: 2, identity: 0.929

gacgcgggcacggtccgcacacgaaggc	CRISPR spacer
gacgcgggcacggtccgcagacgaaagc	Protospacer
******************* *****.**

232. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 1822045-1822078, mismatch: 2, identity: 0.941

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgctttcgtctgcgggccgctggtggc	Protospacer
*********.***************** ******

233. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3362230-3362263, mismatch: 2, identity: 0.941

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaccccgttttcgtctgcggaccgcaggtggc	Protospacer
**** *****************.***********

234. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3795491-3795524, mismatch: 2, identity: 0.941

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcgtctgcgggccgtgggtggc	Protospacer
**************************..******

235. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3795552-3795585, mismatch: 2, identity: 0.941

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcgtctgcgggccgtgggtggc	Protospacer
**************************..******

236. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3795613-3795646, mismatch: 2, identity: 0.941

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcgtctgcgggccgtgggtggc	Protospacer
**************************..******

237. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3795674-3795707, mismatch: 2, identity: 0.941

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcgtctgcgggccgtgggtggc	Protospacer
**************************..******

238. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3795735-3795768, mismatch: 2, identity: 0.941

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcgtctgcgggccgtgggtggc	Protospacer
**************************..******

239. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3795796-3795829, mismatch: 2, identity: 0.941

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcgtctgcgggccgtgggtggc	Protospacer
**************************..******

240. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3795857-3795890, mismatch: 2, identity: 0.941

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcgtctgcgggccgtgggtggc	Protospacer
**************************..******

241. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to position: 3795918-3795951, mismatch: 2, identity: 0.941

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
gaaaacccgttttcgtctgcgggccgtgggtggc	Protospacer
**************************..******

242. spacer 21.1|3487093|34|CP032698|CRISPRCasFinder matches to position: 3818731-3818764, mismatch: 2, identity: 0.941

gaaaacccgttctcatctgcggaccgtgcgtggc	CRISPR spacer
gaaaacccgttttcgtctgcggaccgtgcgtggc	Protospacer
***********.**.*******************

243. spacer 21.1|3487093|34|CP032698|CRISPRCasFinder matches to position: 3992622-3992655, mismatch: 2, identity: 0.941

gaaaacccgttctcatctgcggaccgtgcgtggc	CRISPR spacer
gaaaacccgttctcgtctgccgaccgtgcgtggc	Protospacer
**************.***** *************

244. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 3756060-3756095, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacctgcggcccgcagacgaagacgggtttt	Protospacer
*********.**************** *********

245. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 3795488-3795523, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccacggcccgcagacgaaaacgggtttt	Protospacer
**********.*************** *********

246. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 3795549-3795584, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccacggcccgcagacgaaaacgggtttt	Protospacer
**********.*************** *********

247. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 3795610-3795645, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccacggcccgcagacgaaaacgggtttt	Protospacer
**********.*************** *********

248. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 3795671-3795706, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccacggcccgcagacgaaaacgggtttt	Protospacer
**********.*************** *********

249. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 3795732-3795767, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccacggcccgcagacgaaaacgggtttt	Protospacer
**********.*************** *********

250. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 3795793-3795828, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccacggcccgcagacgaaaacgggtttt	Protospacer
**********.*************** *********

251. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 3795854-3795889, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccacggcccgcagacgaaaacgggtttt	Protospacer
**********.*************** *********

252. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 3795915-3795950, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccacggcccgcagacgaaaacgggtttt	Protospacer
**********.*************** *********

253. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 4008398-4008433, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacctgcggcccgcagacgaaaacgggtttt	Protospacer
*********.**************** *********

254. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 4189880-4189915, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccacggcccgcagacgaaaacgggtttt	Protospacer
**********.*************** *********

255. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 4422483-4422518, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccacggcccgcagacgaaaacgggtttt	Protospacer
**********.*************** *********

256. spacer 23.2|3570331|36|CP032698|PILER-CR matches to position: 4916367-4916402, mismatch: 2, identity: 0.944

ccagccacccgcggcccgcagacgaacacgggtttt	CRISPR spacer
ccagccacccgcggcccgcggacgaagacgggtttt	Protospacer
*******************.****** *********

257. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 2936191-2936219, mismatch: 2, identity: 0.931

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgaccctgcgggccgtgccccctt	Protospacer
****************.******** ***

258. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 3157233-3157261, mismatch: 2, identity: 0.931

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgatcctgcggaccgtgctcgctt	Protospacer
********.**************.*****

259. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 4189825-4189853, mismatch: 2, identity: 0.931

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgatcctgcggaccgtgctcgctt	Protospacer
********.**************.*****

260. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 4776925-4776953, mismatch: 2, identity: 0.931

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgaacctgcggaccgtgctcgctt	Protospacer
******** **************.*****

261. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 5763951-5763979, mismatch: 2, identity: 0.931

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgatcctgcggaccgtgctcgctt	Protospacer
********.**************.*****

262. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 6295099-6295127, mismatch: 2, identity: 0.931

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgaccctgcggaccgtggtcgctt	Protospacer
********************** .*****

263. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 6364976-6365004, mismatch: 2, identity: 0.931

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgatcctgcggaccgtgctcgctt	Protospacer
********.**************.*****

264. spacer 25.2|3679888|29|CP032698|PILER-CR matches to position: 6394768-6394796, mismatch: 2, identity: 0.931

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cctctcgatcctgcggaccgtgctcgctt	Protospacer
********.**************.*****

265. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 2936131-2936163, mismatch: 2, identity: 0.939

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccccgcacggcccgcaggcgaaagcgggt	Protospacer
****** ************** ***********

266. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 3327864-3327896, mismatch: 2, identity: 0.939

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagtcacgcacggcccgcagccgaaaacgggt	Protospacer
****.**********************.*****

267. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 3568222-3568254, mismatch: 2, identity: 0.939

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacggcccgcagacgaaaacgggt	Protospacer
********************* *****.*****

268. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 3838673-3838705, mismatch: 2, identity: 0.939

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacggcccgcagacgaaaacgggt	Protospacer
********************* *****.*****

269. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 4020184-4020216, mismatch: 2, identity: 0.939

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacgacccgcagacgaaagcgggt	Protospacer
*************.******* ***********

270. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 4607013-4607045, mismatch: 2, identity: 0.939

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacggcccgcagtcgaaagggggt	Protospacer
*********************.****** ****

271. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 5326503-5326535, mismatch: 2, identity: 0.939

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcaaggcccgcagccgaaaacgggt	Protospacer
*********** ***************.*****

272. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 5627693-5627725, mismatch: 2, identity: 0.939

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacgacccgcagccgaaaacgggt	Protospacer
*************.*************.*****

273. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 5862102-5862134, mismatch: 2, identity: 0.939

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacggtccgcagccgaaaacgggt	Protospacer
**************.************.*****

274. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to position: 6554566-6554598, mismatch: 2, identity: 0.939

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcacggcccgcagacgaaaacgggt	Protospacer
********************* *****.*****

275. spacer 27.3|3746550|35|CP032698|CRT matches to position: 5964623-5964657, mismatch: 2, identity: 0.943

aacccgccttcgtccgcgggccgtgcgtggctggg	CRISPR spacer
aacccgttttcgtccgcgggccgtgcgtggctggg	Protospacer
******..***************************

276. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 1822048-1822067, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgctttcgtctgcggg	Protospacer
*******.******.*****

277. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 3675885-3675904, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgctttcgtctgcggg	Protospacer
*******.******.*****

278. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 3756062-3756081, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgtcttcgtctgcggg	Protospacer
******.*******.*****

279. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 3880351-3880370, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aaccccctttcgtccgcggg	Protospacer
***** *.************

280. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 3992510-3992529, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgctttcgtctgcggg	Protospacer
*******.******.*****

281. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 4020198-4020217, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgctttcgtctgcggg	Protospacer
*******.******.*****

282. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 4502929-4502948, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgtcttcgtctgcggg	Protospacer
******.*******.*****

283. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 4844040-4844059, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgcctccgtccgcagg	Protospacer
*********.*******.**

284. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 5012388-5012407, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgccttcgcctgcggg	Protospacer
************.*.*****

285. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 5054925-5054944, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aaccccctttcgtccgcggg	Protospacer
***** *.************

286. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 5514260-5514279, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgctttcgtcctcggg	Protospacer
*******.******* ****

287. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 5964524-5964543, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgctctcgtccgcggg	Protospacer
*******..***********

288. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 5964581-5964600, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgttttcgtccgcggg	Protospacer
******..************

289. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 5964638-5964657, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgttttcgtccgcggg	Protospacer
******..************

290. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 5964695-5964714, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgctctcgtccgcggg	Protospacer
*******..***********

291. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 5964752-5964771, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgttttcgtccgcggg	Protospacer
******..************

292. spacer 27.5|3746576|20|CP032698|PILER-CR matches to position: 6047979-6047998, mismatch: 2, identity: 0.9

aacccgccttcgtccgcggg	CRISPR spacer
aacccgctttcgtctgcggg	Protospacer
*******.******.*****

293. spacer 34.4|4013847|36|CP032698|CRT matches to position: 3838629-3838664, mismatch: 2, identity: 0.944

aaaaccctcggtcacgtgcggaccgtgctcgcttct	CRISPR spacer
aaaacccccggtcatgtgcggaccgtgctcgcttct	Protospacer
*******.******.*********************

294. spacer 34.5|4013903|37|CP032698|CRT matches to position: 3756001-3756037, mismatch: 2, identity: 0.946

aaaaccctctcaatcccgcggaccgtgggtggctggt	CRISPR spacer
aaaaccctctcgatcctgcggaccgtgggtggctggt	Protospacer
***********.****.********************

295. spacer 34.9|4014032|20|CP032698|PILER-CR matches to position: 3585727-3585746, mismatch: 2, identity: 0.9

acccctctcgatcccgcgga	CRISPR spacer
acccctctcgaccctgcgga	Protospacer
***********.**.*****

296. spacer 34.9|4014032|20|CP032698|PILER-CR matches to position: 3892460-3892479, mismatch: 2, identity: 0.9

acccctctcgatcccgcgga	CRISPR spacer
acccctctcgaccctgcgga	Protospacer
***********.**.*****

297. spacer 34.9|4014032|20|CP032698|PILER-CR matches to position: 5847494-5847513, mismatch: 2, identity: 0.9

acccctctcgatcccgcgga	CRISPR spacer
acccctctcgattctgcgga	Protospacer
************.*.*****

298. spacer 34.10|4014090|20|CP032698|PILER-CR matches to position: 5999384-5999403, mismatch: 2, identity: 0.9

aacccgttttcgtcctcgcg	CRISPR spacer
aacccgttttcgtccgcacg	Protospacer
*************** *.**

299. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 3795494-3795523, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggcccgcagacgaaaacgggtttt	Protospacer
****.********** **************

300. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 3795555-3795584, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggcccgcagacgaaaacgggtttt	Protospacer
****.********** **************

301. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 3795616-3795645, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggcccgcagacgaaaacgggtttt	Protospacer
****.********** **************

302. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 3795677-3795706, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggcccgcagacgaaaacgggtttt	Protospacer
****.********** **************

303. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 3795738-3795767, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggcccgcagacgaaaacgggtttt	Protospacer
****.********** **************

304. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 3795799-3795828, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggcccgcagacgaaaacgggtttt	Protospacer
****.********** **************

305. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 3795860-3795889, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggcccgcagacgaaaacgggtttt	Protospacer
****.********** **************

306. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 3795921-3795950, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggcccgcagacgaaaacgggtttt	Protospacer
****.********** **************

307. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 4008404-4008433, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acctgcggcccgcagacgaaaacgggtttt	Protospacer
***.*********** **************

308. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 4136299-4136328, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggtccgcagccgaaaacgggtttt	Protospacer
****.***.*********************

309. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 4189886-4189915, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggcccgcagacgaaaacgggtttt	Protospacer
****.********** **************

310. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 4422483-4422512, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacggcccgcagacgaaaacgggtttt	Protospacer
****.********** **************

311. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 4430419-4430448, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccgcggcccgcaggcgaaaacggggttt	Protospacer
*************** ********** ***

312. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 4959081-4959110, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acccacagcccgcagccgaaaacgggtttt	Protospacer
****.*.***********************

313. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 5445824-5445853, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acgcacggcccgcagccgaaaacgggtttt	Protospacer
** *.*************************

314. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 6260757-6260786, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acctgcggcccgcagccgaaagcgggtttt	Protospacer
***.*****************.********

315. spacer 35.1|4020249|30|CP032698|PILER-CR matches to position: 7052560-7052589, mismatch: 2, identity: 0.933

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
acctgcggcccgcaggcgaaaacgggtttt	Protospacer
***.*********** **************

316. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 3568172-3568199, mismatch: 2, identity: 0.929

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcagggtcgagagggttt	Protospacer
*************** ********* **

317. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 3568288-3568315, mismatch: 2, identity: 0.929

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcaggatcgagagggttt	Protospacer
*************** ********* **

318. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 3919347-3919374, mismatch: 2, identity: 0.929

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcagggtcgagagggttt	Protospacer
*************** ********* **

319. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 4787743-4787770, mismatch: 2, identity: 0.929

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcagggtcgagagggttt	Protospacer
*************** ********* **

320. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 4787858-4787885, mismatch: 2, identity: 0.929

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcagggtcgagagggttt	Protospacer
*************** ********* **

321. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 5788923-5788950, mismatch: 2, identity: 0.929

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcaggatcgagagggttt	Protospacer
*************** ********* **

322. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 5847493-5847520, mismatch: 2, identity: 0.929

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcagaatcgagaggggtt	Protospacer
**************. ************

323. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 5853439-5853466, mismatch: 2, identity: 0.929

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcagggtcgagagggttt	Protospacer
*************** ********* **

324. spacer 35.2|4020307|28|CP032698|PILER-CR matches to position: 5853554-5853581, mismatch: 2, identity: 0.929

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
ggcacggtccgcaggatcgagagggttt	Protospacer
*************** ********* **

325. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 3157232-3157261, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgagcacggtccgcaggatcgagagg	Protospacer
** ***.***********************

326. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 3568166-3568195, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgggcacggtccgcagggtcgagagg	Protospacer
** ******************.********

327. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 3919351-3919380, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgggcacggtccgcagggtcgagagg	Protospacer
** ******************.********

328. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 4189824-4189853, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgagcacggtccgcaggatcgagagg	Protospacer
** ***.***********************

329. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 4787737-4787766, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgggcacggtccgcagggtcgagagg	Protospacer
** ******************.********

330. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 4787852-4787881, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgggcacggtccgcagggtcgagagg	Protospacer
** ******************.********

331. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 4967522-4967551, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gacgcgggcacggtccgcagattcgagagg	Protospacer
********************. ********

332. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 5763950-5763979, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgagcacggtccgcaggatcgagagg	Protospacer
** ***.***********************

333. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 5853443-5853472, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgggcacggtccgcagggtcgagagg	Protospacer
** ******************.********

334. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 6364975-6365004, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgagcacggtccgcaggatcgagagg	Protospacer
** ***.***********************

335. spacer 38.1|4133520|30|CP032698|PILER-CR matches to position: 6394768-6394797, mismatch: 2, identity: 0.933

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gaagcgagcacggtccgcaggatcgagagg	Protospacer
** ***.***********************

336. spacer 38.2|4133580|30|CP032698|PILER-CR matches to position: 3157348-3157377, mismatch: 2, identity: 0.933

ccacctgcgggccgcagacgaaaacaggtt	CRISPR spacer
ccacctgcgggccgcagacgaaagcgggtt	Protospacer
***********************.*.****

337. spacer 38.2|4133580|30|CP032698|PILER-CR matches to position: 3662307-3662336, mismatch: 2, identity: 0.933

ccacctgcgggccgcagacgaaaacaggtt	CRISPR spacer
ccacctgcggcccgcagacgaaaacgggtt	Protospacer
********** **************.****

338. spacer 38.2|4133580|30|CP032698|PILER-CR matches to position: 4008402-4008431, mismatch: 2, identity: 0.933

ccacctgcgggccgcagacgaaaacaggtt	CRISPR spacer
ccacctgcggcccgcagacgaaaacgggtt	Protospacer
********** **************.****

339. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 1230391-1230421, mismatch: 2, identity: 0.935

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgagcacggcccgcaggatcgagaggggtta	Protospacer
**.******.*********************

340. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 3157236-3157266, mismatch: 2, identity: 0.935

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgagcacggtccgcaggatcgagagggttta	Protospacer
**.************************ ***

341. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 3568170-3568200, mismatch: 2, identity: 0.935

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcagggtcgagagggttta	Protospacer
*****************.********* ***

342. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 3892458-3892488, mismatch: 2, identity: 0.935

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgagcacggtccgcagggtcgagaggggtta	Protospacer
**.**************.*************

343. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 3919346-3919376, mismatch: 2, identity: 0.935

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcagggtcgagagggttta	Protospacer
*****************.********* ***

344. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 4787741-4787771, mismatch: 2, identity: 0.935

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcagggtcgagagggttta	Protospacer
*****************.********* ***

345. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 4787856-4787886, mismatch: 2, identity: 0.935

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcagggtcgagagggttta	Protospacer
*****************.********* ***

346. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 4967517-4967547, mismatch: 2, identity: 0.935

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcagattcgagaggggtta	Protospacer
****************. *************

347. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 5763954-5763984, mismatch: 2, identity: 0.935

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgagcacggtccgcaggatcgagagggttta	Protospacer
**.************************ ***

348. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to position: 5853438-5853468, mismatch: 2, identity: 0.935

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcagggtcgagagggttta	Protospacer
*****************.********* ***

349. spacer 39.1|4136122|49|CP032698|CRISPRCasFinder matches to position: 2628404-2628452, mismatch: 2, identity: 0.959

aggcacctcgcccacccgcccgcccgtgcagcgggttggttggttccgg	CRISPR spacer
aggcacctcccccacccacccgcccgtgcagcgggttggttggttccgg	Protospacer
********* *******.*******************************

350. spacer 42.1|4174644|38|CP032698|CRT matches to position: 3568452-3568489, mismatch: 2, identity: 0.947

gaccagccacctgcggcccgcagacgaaaacggttttt	CRISPR spacer
gaccagccacccgcggcccgcagacgaaaacgggtttt	Protospacer
***********.********************* ****

351. spacer 42.1|4174644|38|CP032698|CRT matches to position: 3847530-3847567, mismatch: 2, identity: 0.947

gaccagccacctgcggcccgcagacgaaaacggttttt	CRISPR spacer
gaccagccacctgcggcccgcagacgaaaacgcgtttt	Protospacer
********************************  ****

352. spacer 42.1|4174644|38|CP032698|CRT matches to position: 5853381-5853418, mismatch: 2, identity: 0.947

gaccagccacctgcggcccgcagacgaaaacggttttt	CRISPR spacer
gaccagccacctgcggcccgcagacgaaaacggggttt	Protospacer
*********************************  ***

353. spacer 42.1|4174644|38|CP032698|CRT matches to position: 7052560-7052597, mismatch: 2, identity: 0.947

gaccagccacctgcggcccgcagacgaaaacggttttt	CRISPR spacer
gaccagccacctgcggcccgcaggcgaaaacgggtttt	Protospacer
***********************.********* ****

354. spacer 42.3|4174756|36|CP032698|CRT matches to position: 4801236-4801271, mismatch: 2, identity: 0.944

gagaagcgaccacgacccgcagattcgagagggttt	CRISPR spacer
gagaagcgaccacgacccgcaggatcgagagggttt	Protospacer
**********************. ************

355. spacer 42.5|4174757|36|CP032698|PILER-CR matches to position: 4801236-4801271, mismatch: 2, identity: 0.944

gagaagcgaccacgacccgcagattcgagagggttt	CRISPR spacer
gagaagcgaccacgacccgcaggatcgagagggttt	Protospacer
**********************. ************

356. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 3157233-3157265, mismatch: 2, identity: 0.939

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgatcctgcggaccgtgctcgctt	Protospacer
******.********************.*****

357. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 3568167-3568199, mismatch: 2, identity: 0.939

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgaccctgcggaccgtgcccgctt	Protospacer
******.*****.********************

358. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 3919347-3919379, mismatch: 2, identity: 0.939

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgaccctgcggaccgtgcccgctt	Protospacer
******.*****.********************

359. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 4787738-4787770, mismatch: 2, identity: 0.939

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgaccctgcggaccgtgcccgctt	Protospacer
******.*****.********************

360. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 4787853-4787885, mismatch: 2, identity: 0.939

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgaccctgcggaccgtgcccgctt	Protospacer
******.*****.********************

361. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 5763951-5763983, mismatch: 2, identity: 0.939

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgatcctgcggaccgtgctcgctt	Protospacer
******.********************.*****

362. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 5853439-5853471, mismatch: 2, identity: 0.939

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgaccctgcggaccgtgcccgctt	Protospacer
******.*****.********************

363. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to position: 6394764-6394796, mismatch: 2, identity: 0.939

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
aaaccctctcgatcctgcggaccgtgctcgctt	Protospacer
******.********************.*****

364. spacer 46.1|4443766|53|CP032698|CRISPRCasFinder matches to position: 2853239-2853291, mismatch: 2, identity: 0.962

gggcccggaaccatccaaccccggggcacgggcgggtgggtgggcgacgtgcc	CRISPR spacer
gggcccggaaccatcaaaccccggggcacgggcgggtgggtgggcgaggtgcc	Protospacer
*************** ******************************* *****

365. spacer 47.1|4480725|33|CP032698|PILER-CR,CRT matches to position: 4422487-4422519, mismatch: 2, identity: 0.939

cccagccacgcacgacccgcagacgaaaacggg	CRISPR spacer
cccagccacccacggcccgcagacgaaaacggg	Protospacer
********* ****.******************

366. spacer 47.1|4480725|33|CP032698|PILER-CR,CRT matches to position: 5090837-5090869, mismatch: 2, identity: 0.939

cccagccacgcacgacccgcagacgaaaacggg	CRISPR spacer
cccagccacgcacggctcgcagacgaaaacggg	Protospacer
**************.*.****************

367. spacer 47.1|4480725|33|CP032698|PILER-CR,CRT matches to position: 5964623-5964655, mismatch: 2, identity: 0.939

cccagccacgcacgacccgcagacgaaaacggg	CRISPR spacer
cccagccacgcacggcccgcggacgaaaacggg	Protospacer
**************.*****.************

368. spacer 47.1|4480725|33|CP032698|PILER-CR,CRT matches to position: 6182582-6182614, mismatch: 2, identity: 0.939

cccagccacgcacgacccgcagacgaaaacggg	CRISPR spacer
cccagccacccacggcccgcagacgaaaacggg	Protospacer
********* ****.******************

369. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 1978457-1978488, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagccagcacggtccgcaggttcgagaggg	Protospacer
****** .************************

370. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 3157231-3157262, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgagcacggtccgcaggatcgagaggg	Protospacer
*******.************** *********

371. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 3892462-3892493, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgagcacggtccgcagggtcgagaggg	Protospacer
*******.************** *********

372. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 4189823-4189854, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgagcacggtccgcaggatcgagaggg	Protospacer
*******.************** *********

373. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 4967521-4967552, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agacgcgggcacggtccgcagattcgagaggg	Protospacer
*** *****************.**********

374. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 5038005-5038036, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agacgcgggcacggtccgcaggatcgagaggg	Protospacer
*** ****************** *********

375. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 5326218-5326249, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcagcttcgagcggg	Protospacer
********************* ****** ***

376. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 5627806-5627837, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcaggtgcgagcggg	Protospacer
*********************** **** ***

377. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 5652387-5652418, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgagcacggtccgcagattcgagaggg	Protospacer
*******.*************.**********

378. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 5763949-5763980, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgagcacggtccgcaggatcgagaggg	Protospacer
*******.************** *********

379. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 6364974-6365005, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgagcacggtccgcaggatcgagaggg	Protospacer
*******.************** *********

380. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to position: 6394767-6394798, mismatch: 2, identity: 0.938

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgagcacggtccgcaggatcgagaggg	Protospacer
*******.************** *********

381. spacer 47.3|4480838|36|CP032698|PILER-CR,CRT matches to position: 5406183-5406218, mismatch: 2, identity: 0.944

cccagccacgcacggcccgcagacgaaaacgggttt	CRISPR spacer
cccagccacgcacgacccgcagacgaaaacggggtt	Protospacer
**************.****************** **

382. spacer 47.3|4480838|36|CP032698|PILER-CR,CRT matches to position: 5488664-5488699, mismatch: 2, identity: 0.944

cccagccacgcacggcccgcagacgaaaacgggttt	CRISPR spacer
cccagccacgcacggtccgcagtcgaaaacgggttt	Protospacer
***************.****** *************

383. spacer 47.3|4480838|36|CP032698|PILER-CR,CRT matches to position: 5821763-5821798, mismatch: 2, identity: 0.944

cccagccacgcacggcccgcagacgaaaacgggttt	CRISPR spacer
cccagccacacacgacccgcagacgaaaacgggttt	Protospacer
*********.****.*********************

384. spacer 47.3|4480838|36|CP032698|PILER-CR,CRT matches to position: 5862101-5862136, mismatch: 2, identity: 0.944

cccagccacgcacggcccgcagacgaaaacgggttt	CRISPR spacer
cccagccacgcacggtccgcagccgaaaacgggttt	Protospacer
***************.****** *************

385. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 1539395-1539415, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

386. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 1539546-1539566, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

387. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 1693722-1693742, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

388. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 1693837-1693857, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacacacggcccgcag	Protospacer
****** * ************

389. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 1807861-1807881, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagcccgccacggtccgcag	Protospacer
******* ******.******

390. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 1978688-1978708, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggtccgcag	Protospacer
******** *****.******

391. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 2624545-2624565, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

392. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 2668957-2668977, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacacacggcccgcag	Protospacer
****** * ************

393. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 2818744-2818764, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacacacggcccgcag	Protospacer
****** * ************

394. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 2967359-2967379, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccaccgcccgcag	Protospacer
****** ***** ********

395. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 2967439-2967459, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccaccgcccgcag	Protospacer
****** ***** ********

396. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3064834-3064854, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagcccacgacggcccgcag	Protospacer
******* * ***********

397. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3282270-3282290, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggtccgcag	Protospacer
******** *****.******

398. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3318447-3318467, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggtccgcag	Protospacer
******** *****.******

399. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3355544-3355564, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

400. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3568222-3568242, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

401. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3568454-3568474, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccgcggcccgcag	Protospacer
****** ***.**********

402. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3675755-3675775, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgtacggcccgcag	Protospacer
******** .***********

403. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3675871-3675891, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgtacggcccgcag	Protospacer
******** .***********

404. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3677546-3677566, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgtacggcccgcag	Protospacer
******** .***********

405. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3756016-3756036, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggtccgcag	Protospacer
****** *******.******

406. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3795427-3795447, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccactcacggcccgcag	Protospacer
****** *.************

407. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3838685-3838705, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

408. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3892530-3892550, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

409. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3945749-3945769, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccgcggcccgcag	Protospacer
****** ***.**********

410. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 3951945-3951965, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggtccgcag	Protospacer
****** *******.******

411. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4136293-4136313, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggtccgcag	Protospacer
****** *******.******

412. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4147733-4147753, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacgacccgcag	Protospacer
****** ******.*******

413. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4163240-4163260, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggtccgcag	Protospacer
****** *******.******

414. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4163297-4163317, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggtccgcag	Protospacer
****** *******.******

415. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4430413-4430433, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccgcggcccgcag	Protospacer
****** ***.**********

416. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4472278-4472298, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

417. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4492173-4492193, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

418. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4496587-4496607, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacctacggcccgcag	Protospacer
****** **.***********

419. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4607013-4607033, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

420. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4638486-4638506, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacacacggcccgcag	Protospacer
****** * ************

421. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4638543-4638563, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

422. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4638600-4638620, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

423. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4777220-4777240, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagcccgccacggtccgcag	Protospacer
******* ******.******

424. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4787793-4787813, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

425. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4787908-4787928, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

426. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4840662-4840682, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacacacggcccgcag	Protospacer
****** * ************

427. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4959096-4959116, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacagcccgcag	Protospacer
****** *****.********

428. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 4967589-4967609, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

429. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5012401-5012421, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccgcccgcggcccgcag	Protospacer
****** ***.**********

430. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5105458-5105478, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacgacccgcag	Protospacer
****** ******.*******

431. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5145913-5145933, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggtccgcag	Protospacer
****** *******.******

432. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5306826-5306846, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggtccgcag	Protospacer
******** *****.******

433. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5306970-5306990, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggtccgcag	Protospacer
******** *****.******

434. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5342971-5342991, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccccggcccgcag	Protospacer
****** *** **********

435. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5420262-5420282, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggtccgcag	Protospacer
****** *******.******

436. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5445702-5445722, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

437. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5445818-5445838, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

438. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5478075-5478095, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

439. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5478189-5478209, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

440. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5633117-5633137, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccgcggcccgcag	Protospacer
****** ***.**********

441. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5747222-5747242, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacgacccgcag	Protospacer
******** ****.*******

442. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5761379-5761399, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

443. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5789029-5789049, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacgacccgcag	Protospacer
****** ******.*******

444. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5860187-5860207, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagcccgccacggtccgcag	Protospacer
******* ******.******

445. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 5956293-5956313, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggtccgcag	Protospacer
****** *******.******

446. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6182713-6182733, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccaaccacccacggcccgcag	Protospacer
***.** **************

447. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6241510-6241530, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggtccgcag	Protospacer
******** *****.******

448. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6241656-6241676, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggtccgcag	Protospacer
******** *****.******

449. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6261928-6261948, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

450. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6365088-6365108, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

451. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6394663-6394683, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccgcggcccgcag	Protospacer
****** ***.**********

452. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6541527-6541547, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacacacggcccgcag	Protospacer
****** * ************

453. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6554578-6554598, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

454. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6635952-6635972, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggtccgcag	Protospacer
******** *****.******

455. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6902878-6902898, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagcccgccacggtccgcag	Protospacer
******* ******.******

456. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6956943-6956963, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacgacccgcag	Protospacer
****** ******.*******

457. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6963475-6963495, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

458. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6963634-6963654, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

459. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 6984658-6984678, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacgcacggcccgcag	Protospacer
****** * ************

460. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 7020950-7020970, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccgcgcacggcccgcag	Protospacer
****** * ************

461. spacer 50.1|4603161|21|CP032698|PILER-CR matches to position: 7240663-7240683, mismatch: 2, identity: 0.905

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccacggtccgcag	Protospacer
****** *******.******

462. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 1230387-1230417, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcgggccgtgctcgcttc	Protospacer
*****************.******.******

463. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 3157288-3157318, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtgcgggcttc	Protospacer
************************  *****

464. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 3550300-3550330, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcgaaccgtgctcgcttc	Protospacer
****************.*******.******

465. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 3568052-3568082, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtggtcgcttc	Protospacer
*********************** .******

466. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 3568398-3568428, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtggtcgcttc	Protospacer
*********************** .******

467. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 3702705-3702735, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctcttgatcctgcggaccgtgctcgcttc	Protospacer
******.*****************.******

468. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 3892462-3892492, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgaccctgcggaccgtgctcgcttc	Protospacer
*********.**************.******

469. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 4603249-4603279, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccccctcgatcctgcggaccgtgctcgcttc	Protospacer
***.********************.******

470. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 4776924-4776954, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgaacctgcggaccgtgctcgcttc	Protospacer
********* **************.******

471. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 5847496-5847526, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgattctgcggaccgtgcccgcgtc	Protospacer
**********.***************** **

472. spacer 53.1|4844099|31|CP032698|PILER-CR matches to position: 6475136-6475166, mismatch: 2, identity: 0.935

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
ccctctcgatcctgcggaccgtggtcgcttc	Protospacer
*********************** .******

473. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 3362227-3362250, mismatch: 2, identity: 0.917

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaccccgttttcgtctgcg	Protospacer
******* *****.**********

474. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 4204592-4204615, mismatch: 2, identity: 0.917

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaccccgttttcgtctgcg	Protospacer
******* *****.**********

475. spacer 53.2|4844171|24|CP032698|PILER-CR matches to position: 5445834-5445857, mismatch: 2, identity: 0.917

caagaaaacccgtcttcgtctgcg	CRISPR spacer
caagaaaacccgttttcggctgcg	Protospacer
*************.**** *****

476. spacer 55.3|4866586|37|CP032698|PILER-CR matches to position: 1821876-1821912, mismatch: 2, identity: 0.946

agaagcgagcacggtccgcacgtgaccgggggttttg	CRISPR spacer
agaagcgaccacggtccgcacatgaccgggggttttg	Protospacer
******** ************.***************

477. spacer 55.3|4866586|37|CP032698|PILER-CR matches to position: 3585768-3585804, mismatch: 2, identity: 0.946

agaagcgagcacggtccgcacgtgaccgggggttttg	CRISPR spacer
agaagcgggcacggtccgcacgtgaccgagggttttg	Protospacer
*******.********************.********

478. spacer 55.3|4866586|37|CP032698|PILER-CR matches to position: 4607070-4607106, mismatch: 2, identity: 0.946

agaagcgagcacggtccgcacgtgaccgggggttttg	CRISPR spacer
agaagcgagcacggtccgcacatgaccgagggttttg	Protospacer
*********************.******.********

479. spacer 55.3|4866586|37|CP032698|PILER-CR matches to position: 5069726-5069762, mismatch: 2, identity: 0.946

agaagcgagcacggtccgcacgtgaccgggggttttg	CRISPR spacer
agaagcgaccacggcccgcacgtgaccgggggttttg	Protospacer
******** *****.**********************

480. spacer 58.1|5049170|37|CP032698|PILER-CR,CRT matches to position: 3327860-3327896, mismatch: 2, identity: 0.946

ccagccacgcacggcccgcagtcgaaaacgggtttcc	CRISPR spacer
ccagtcacgcacggcccgcagccgaaaacgggtttcc	Protospacer
****.****************.***************

481. spacer 59.1|5075217|32|CP032698|CRISPRCasFinder matches to position: 3568052-3568083, mismatch: 2, identity: 0.938

gaagcgaccacgacccgcaggatcgagagggt	CRISPR spacer
gaagcgaccacggtccgcaggatcgagagggt	Protospacer
************..******************

482. spacer 59.1|5075217|32|CP032698|CRISPRCasFinder matches to position: 3568398-3568429, mismatch: 2, identity: 0.938

gaagcgaccacgacccgcaggatcgagagggt	CRISPR spacer
gaagcgaccacggtccgcaggatcgagagggt	Protospacer
************..******************

483. spacer 59.1|5075217|32|CP032698|CRISPRCasFinder matches to position: 3983464-3983495, mismatch: 2, identity: 0.938

gaagcgaccacgacccgcaggatcgagagggt	CRISPR spacer
gaagcgaccacggcccgcaggatcgagggggt	Protospacer
************.**************.****

484. spacer 59.1|5075217|32|CP032698|CRISPRCasFinder matches to position: 5445762-5445793, mismatch: 2, identity: 0.938

gaagcgaccacgacccgcaggatcgagagggt	CRISPR spacer
gaagcgaccacggcccgcaggaccgagagggt	Protospacer
************.*********.*********

485. spacer 59.1|5075217|32|CP032698|CRISPRCasFinder matches to position: 6475135-6475166, mismatch: 2, identity: 0.938

gaagcgaccacgacccgcaggatcgagagggt	CRISPR spacer
gaagcgaccacggtccgcaggatcgagagggt	Protospacer
************..******************

486. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 3282270-3282304, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccccgcacggtccgcagacgaaaacgggttt	Protospacer
****** ************** *************

487. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 3327862-3327896, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagtcacgcacggcccgcagccgaaaacgggttt	Protospacer
****.*********.********************

488. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 3467242-3467276, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggtccgcagccgaaaccggggtt	Protospacer
*************************** **** **

489. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 3568222-3568256, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggcccgcagacgaaaacgggttt	Protospacer
**************.****** *************

490. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 3838671-3838705, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggcccgcagacgaaaacgggttt	Protospacer
**************.****** *************

491. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 3919405-3919439, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggtccgcagtcgaagacgggttt	Protospacer
*********************.****.********

492. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 3961695-3961729, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggtccgcagccgaaaccggggtt	Protospacer
*************************** **** **

493. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 5326501-5326535, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcaaggcccgcagccgaaaacgggttt	Protospacer
*********** **.********************

494. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 5420262-5420296, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacccacggtccgcagacgaaaacgggttt	Protospacer
******** ************ *************

495. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 5503169-5503203, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggtccgcggacgaaaacgggttt	Protospacer
*******************.* *************

496. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 5843887-5843921, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggtccgcagacgaagacgggttt	Protospacer
********************* ****.********

497. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 5853497-5853531, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggtccgcgggcgaaaacgggttt	Protospacer
*******************.* *************

498. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 5956279-5956313, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacccacggtccgcagacgaaaacgggttt	Protospacer
******** ************ *************

499. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to position: 6554564-6554598, mismatch: 2, identity: 0.943

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcacggcccgcagacgaaaacgggttt	Protospacer
**************.****** *************

500. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 1821880-1821911, mismatch: 2, identity: 0.938

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gaagcgaccacggtccgcacatgaccgggggt	Protospacer
******. ************************

501. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 3318507-3318538, mismatch: 2, identity: 0.938

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gaagcgaccacggtccgcacatgaccgggggt	Protospacer
******. ************************

502. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 3585772-3585803, mismatch: 2, identity: 0.938

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gaagcgggcacggtccgcacgtgaccgagggt	Protospacer
********************.******.****

503. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 4607071-4607102, mismatch: 2, identity: 0.938

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gaagcgagcacggtccgcacatgaccgagggt	Protospacer
******.********************.****

504. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 5035089-5035120, mismatch: 2, identity: 0.938

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gaagcgagcacggtccgcacgtgaccgggggt	Protospacer
******.*************.***********

505. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 5091010-5091041, mismatch: 2, identity: 0.938

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gacgcgggcacggtccgcacatgaccgagggt	Protospacer
** ************************.****

506. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 5478234-5478265, mismatch: 2, identity: 0.938

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gacgcgagcacggtccgcacatgaccgggggt	Protospacer
** ***.*************************

507. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 5520107-5520138, mismatch: 2, identity: 0.938

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gaagcgggcacggtccgcacacgaccgagggt	Protospacer
*********************.*****.****

508. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to position: 5633049-5633080, mismatch: 2, identity: 0.938

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
gacgcgggcacggtccgcacacgaccgggggt	Protospacer
** ******************.**********

509. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to position: 2052181-2052210, mismatch: 2, identity: 0.933

acccgctttcgggtgcgggccgtggtcgct	CRISPR spacer
acccgttttcggctgcgggccgtggtcgct	Protospacer
*****.****** *****************

510. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to position: 5343069-5343098, mismatch: 2, identity: 0.933

acccgctttcgggtgcgggccgtggtcgct	CRISPR spacer
accccctttcgtgtgcgggccgtggtcgct	Protospacer
**** ****** ******************

511. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to position: 1978574-1978604, mismatch: 2, identity: 0.935

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
aaccctctcgaacctgcgggccgtggtcgct	Protospacer
*****.***** *******************

512. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to position: 3550468-3550498, mismatch: 2, identity: 0.935

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
aacccccttgatcctgcggaccgtggtcgct	Protospacer
********.**********.***********

513. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to position: 3568054-3568084, mismatch: 2, identity: 0.935

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
aaccctctcgatcctgcggaccgtggtcgct	Protospacer
*****.*************.***********

514. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to position: 3568400-3568430, mismatch: 2, identity: 0.935

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
aaccctctcgatcctgcggaccgtggtcgct	Protospacer
*****.*************.***********

515. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to position: 4603251-4603281, mismatch: 2, identity: 0.935

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
aaccccctcgatcctgcggaccgtgctcgct	Protospacer
*******************.***** *****

516. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to position: 4801237-4801267, mismatch: 2, identity: 0.935

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
aaccctctcgatcctgcgggtcgtggtcgct	Protospacer
*****.**************.**********

517. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to position: 5445764-5445794, mismatch: 2, identity: 0.935

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
aaccctctcggtcctgcgggccgtggtcgct	Protospacer
*****.****.********************

518. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to position: 6475134-6475164, mismatch: 2, identity: 0.935

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
aaccctctcgatcctgcggaccgtggtcgct	Protospacer
*****.*************.***********

519. spacer 70.1|5488566|21|CP032698|PILER-CR matches to position: 2483036-2483056, mismatch: 2, identity: 0.905

acccgcagacgaaaacgggtt	CRISPR spacer
acccgcagacgaagacggctt	Protospacer
*************.**** **

520. spacer 70.1|5488566|21|CP032698|PILER-CR matches to position: 4648964-4648984, mismatch: 2, identity: 0.905

acccgcagacgaaaacgggtt	CRISPR spacer
actcgcagacgaacacgggtt	Protospacer
**.********** *******

521. spacer 70.1|5488566|21|CP032698|PILER-CR matches to position: 6295052-6295072, mismatch: 2, identity: 0.905

acccgcagacgaaaacgggtt	CRISPR spacer
acccgcactcgaaaacgggtt	Protospacer
*******  ************

522. spacer 70.1|5488566|21|CP032698|PILER-CR matches to position: 6364927-6364947, mismatch: 2, identity: 0.905

acccgcagacgaaaacgggtt	CRISPR spacer
accggaagacgaaaacgggtt	Protospacer
*** * ***************

523. spacer 70.1|5488566|21|CP032698|PILER-CR matches to position: 6903042-6903062, mismatch: 2, identity: 0.905

acccgcagacgaaaacgggtt	CRISPR spacer
acccgcggacgaaagcgggtt	Protospacer
******.*******.******

524. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 1230386-1230417, mismatch: 2, identity: 0.938

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgagcacggcccgcaggatcgagaggg	Protospacer
******** *************.*********

525. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 3568051-3568082, mismatch: 2, identity: 0.938

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgaccacggtccgcaggatcgagaggg	Protospacer
**************.*******.*********

526. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 3568397-3568428, mismatch: 2, identity: 0.938

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgaccacggtccgcaggatcgagaggg	Protospacer
**************.*******.*********

527. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 3892462-3892493, mismatch: 2, identity: 0.938

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgagcacggtccgcagggtcgagaggg	Protospacer
******** *****.*****************

528. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 3983465-3983496, mismatch: 2, identity: 0.938

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgaccacggcccgcaggatcgaggggg	Protospacer
**********************.*****.***

529. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 3992569-3992600, mismatch: 2, identity: 0.938

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgaccacggcccgcaggtgcgagaggg	Protospacer
**********************  ********

530. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 4801239-4801270, mismatch: 2, identity: 0.938

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgaccacgacccgcaggatcgagaggg	Protospacer
*************.********.*********

531. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 5445761-5445792, mismatch: 2, identity: 0.938

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgaccacggcccgcaggaccgagaggg	Protospacer
**********************..********

532. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 5936536-5936567, mismatch: 2, identity: 0.938

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgaccacggcccgcaggtgcgagaggg	Protospacer
**********************  ********

533. spacer 70.2|5488625|32|CP032698|PILER-CR matches to position: 6475136-6475167, mismatch: 2, identity: 0.938

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
agaagcgaccacggtccgcaggatcgagaggg	Protospacer
**************.*******.*********

534. spacer 71.1|5489850|34|CP032698|CRT matches to position: 5764006-5764039, mismatch: 2, identity: 0.941

gaagcgaccacggcccgcagggtcgggagggttt	CRISPR spacer
gaagcgaccacggcccgcaggatcgagagggttt	Protospacer
*********************.***.********

535. spacer 71.2|5489906|37|CP032698|CRT matches to position: 1822045-1822081, mismatch: 2, identity: 0.946

ccagccacccgcggtccgcagacgaaagcgggttttc	CRISPR spacer
ccagccaccagcggcccgcagacgaaagcgggttttc	Protospacer
********* ****.**********************

536. spacer 71.2|5489906|37|CP032698|CRT matches to position: 3362169-3362205, mismatch: 2, identity: 0.946

ccagccacccgcggtccgcagacgaaagcgggttttc	CRISPR spacer
ccagccacctgcggtccgcagccgaaagcgggttttc	Protospacer
*********.*********** ***************

537. spacer 71.2|5489906|37|CP032698|CRT matches to position: 5420262-5420298, mismatch: 2, identity: 0.946

ccagccacccgcggtccgcagacgaaagcgggttttc	CRISPR spacer
ccagccacccacggtccgcagacgaaaacgggttttc	Protospacer
**********.****************.*********

538. spacer 71.3|5489965|34|CP032698|CRT matches to position: 4801236-4801269, mismatch: 2, identity: 0.941

gaagcgaccacgacccgcaggttcgagtgggttt	CRISPR spacer
gaagcgaccacgacccgcaggatcgagagggttt	Protospacer
********************* ***** ******

539. spacer 71.4|5490021|36|CP032698|CRT matches to position: 2624387-2624422, mismatch: 2, identity: 0.944

ccagccatctgcggcccgcagacgacaacgggtttt	CRISPR spacer
ccagccatctgcggaccgcagacgaaaacgggtttt	Protospacer
************** ********** **********

540. spacer 71.4|5490021|36|CP032698|CRT matches to position: 4008398-4008433, mismatch: 2, identity: 0.944

ccagccatctgcggcccgcagacgacaacgggtttt	CRISPR spacer
ccagccacctgcggcccgcagacgaaaacgggtttt	Protospacer
*******.***************** **********

541. spacer 72.1|5500919|37|CP032698|CRISPRCasFinder matches to position: 1230325-1230361, mismatch: 2, identity: 0.946

cccagccacccacggtccgcagccgaaaacggggttt	CRISPR spacer
cccagccacccgcggtccgcagccgaaaatggggttt	Protospacer
***********.*****************.*******

542. spacer 72.1|5500919|37|CP032698|CRISPRCasFinder matches to position: 3467241-3467277, mismatch: 2, identity: 0.946

cccagccacccacggtccgcagccgaaaacggggttt	CRISPR spacer
cccagccacgcacggtccgcagccgaaaccggggttt	Protospacer
********* ****************** ********

543. spacer 72.1|5500919|37|CP032698|CRISPRCasFinder matches to position: 5862101-5862137, mismatch: 2, identity: 0.946

cccagccacccacggtccgcagccgaaaacggggttt	CRISPR spacer
cccagccacgcacggtccgcagccgaaaacgggtttt	Protospacer
********* *********************** ***

544. spacer 74.1|5520262|49|CP032698|CRISPRCasFinder matches to position: 7389980-7390028, mismatch: 2, identity: 0.959

ccggaaccaaccaacccgctgcacgggcgggtgggtgggcaaaggggct	CRISPR spacer
ccggaaccaaccagcccgctgcacgggcgggtgggtgggcaaagggcct	Protospacer
*************.******************************** **

545. spacer 77.2|5941644|31|CP032698|PILER-CR matches to position: 1821936-1821966, mismatch: 2, identity: 0.935

cccccggtcatgtgcgggccgtggtcgtttt	CRISPR spacer
cccccggtcatgtgcgggccgtagtcgcttt	Protospacer
**********************.****.***

546. spacer 77.3|5941700|32|CP032698|PILER-CR matches to position: 1821991-1822022, mismatch: 2, identity: 0.938

gcccgtgttcgtccgcgggctgtggtcgcgtc	CRISPR spacer
gcccgtgttcgtccgcgggccgtggtcgcttc	Protospacer
********************.******** **

547. spacer 79.1|6011567|33|CP032698|PILER-CR matches to position: 3992566-3992598, mismatch: 2, identity: 0.939

aaaccctcccgaacctgcgggccgtggtcgctt	CRISPR spacer
aaaccctctcgcacctgcgggccgtggtcgctt	Protospacer
********.** *********************

548. spacer 79.1|6011567|33|CP032698|PILER-CR matches to position: 5764007-5764039, mismatch: 2, identity: 0.939

aaaccctcccgaacctgcgggccgtggtcgctt	CRISPR spacer
aaaccctctcgatcctgcgggccgtggtcgctt	Protospacer
********.*** ********************

549. spacer 79.1|6011567|33|CP032698|PILER-CR matches to position: 5936533-5936565, mismatch: 2, identity: 0.939

aaaccctcccgaacctgcgggccgtggtcgctt	CRISPR spacer
aaaccctctcgcacctgcgggccgtggtcgctt	Protospacer
********.** *********************

550. spacer 79.2|6011623|37|CP032698|PILER-CR matches to position: 6394820-6394856, mismatch: 2, identity: 0.946

aagaaacccgttttcgtctgcgggccgtacgtggctg	CRISPR spacer
aagaaacccgttttcgtctgcgggccgtgggtggctg	Protospacer
****************************. *******

551. spacer 79.3|6011683|32|CP032698|PILER-CR matches to position: 3570221-3570252, mismatch: 2, identity: 0.938

ggcaggactggtgccggcccggacgggacttg	CRISPR spacer
ggcaggactggtgccgggccgggcgggacttg	Protospacer
***************** ****.*********

552. spacer 84.1|6088620|47|CP032698|CRISPRCasFinder matches to position: 4480485-4480531, mismatch: 2, identity: 0.957

ggcacctcgcccacccacccgcccgtgcagcgggttgaagggttcgg	CRISPR spacer
ggcacgtcgcccacccacccgcccgtgcagcgcgttgaagggttcgg	Protospacer
***** ************************** **************

553. spacer 85.2|6253198|31|CP032698|CRT matches to position: 3568282-3568312, mismatch: 2, identity: 0.935

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgatcctgcggaccgtgcccgcttc	Protospacer
*********.****************** **

554. spacer 85.2|6253198|31|CP032698|CRT matches to position: 3892462-3892492, mismatch: 2, identity: 0.935

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgaccctgcggaccgtgctcgcttc	Protospacer
************************.*** **

555. spacer 85.2|6253198|31|CP032698|CRT matches to position: 4967521-4967551, mismatch: 2, identity: 0.935

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgaatctgcggaccgtgcccgcgtc	Protospacer
********* .********************

556. spacer 85.2|6253198|31|CP032698|CRT matches to position: 5788926-5788956, mismatch: 2, identity: 0.935

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgatcctgcggaccgtgcccgcttc	Protospacer
*********.****************** **

557. spacer 85.2|6253198|31|CP032698|CRT matches to position: 5847496-5847526, mismatch: 2, identity: 0.935

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgattctgcggaccgtgcccgcgtc	Protospacer
*********..********************

558. spacer 85.2|6253198|31|CP032698|CRT matches to position: 5853557-5853587, mismatch: 2, identity: 0.935

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccctctcgatcctgcggaccgtgcccgcttc	Protospacer
*********.****************** **

559. spacer 85.3|6253254|36|CP032698|CRT matches to position: 3795488-3795523, mismatch: 2, identity: 0.944

aaaacccgctttcgtctgcgggccgtggctggctgg	CRISPR spacer
aaaacccgttttcgtctgcgggccgtgggtggctgg	Protospacer
********.******************* *******

560. spacer 85.3|6253254|36|CP032698|CRT matches to position: 3795549-3795584, mismatch: 2, identity: 0.944

aaaacccgctttcgtctgcgggccgtggctggctgg	CRISPR spacer
aaaacccgttttcgtctgcgggccgtgggtggctgg	Protospacer
********.******************* *******

561. spacer 85.3|6253254|36|CP032698|CRT matches to position: 3795610-3795645, mismatch: 2, identity: 0.944

aaaacccgctttcgtctgcgggccgtggctggctgg	CRISPR spacer
aaaacccgttttcgtctgcgggccgtgggtggctgg	Protospacer
********.******************* *******

562. spacer 85.3|6253254|36|CP032698|CRT matches to position: 3795671-3795706, mismatch: 2, identity: 0.944

aaaacccgctttcgtctgcgggccgtggctggctgg	CRISPR spacer
aaaacccgttttcgtctgcgggccgtgggtggctgg	Protospacer
********.******************* *******

563. spacer 85.3|6253254|36|CP032698|CRT matches to position: 3795732-3795767, mismatch: 2, identity: 0.944

aaaacccgctttcgtctgcgggccgtggctggctgg	CRISPR spacer
aaaacccgttttcgtctgcgggccgtgggtggctgg	Protospacer
********.******************* *******

564. spacer 85.3|6253254|36|CP032698|CRT matches to position: 3795793-3795828, mismatch: 2, identity: 0.944

aaaacccgctttcgtctgcgggccgtggctggctgg	CRISPR spacer
aaaacccgttttcgtctgcgggccgtgggtggctgg	Protospacer
********.******************* *******

565. spacer 85.3|6253254|36|CP032698|CRT matches to position: 3795854-3795889, mismatch: 2, identity: 0.944

aaaacccgctttcgtctgcgggccgtggctggctgg	CRISPR spacer
aaaacccgttttcgtctgcgggccgtgggtggctgg	Protospacer
********.******************* *******

566. spacer 85.3|6253254|36|CP032698|CRT matches to position: 3795915-3795950, mismatch: 2, identity: 0.944

aaaacccgctttcgtctgcgggccgtggctggctgg	CRISPR spacer
aaaacccgttttcgtctgcgggccgtgggtggctgg	Protospacer
********.******************* *******

567. spacer 85.3|6253254|36|CP032698|CRT matches to position: 4189880-4189915, mismatch: 2, identity: 0.944

aaaacccgctttcgtctgcgggccgtggctggctgg	CRISPR spacer
aaaacccgttttcgtctgcgggccgtgggtggctgg	Protospacer
********.******************* *******

568. spacer 85.3|6253254|36|CP032698|CRT matches to position: 4422483-4422518, mismatch: 2, identity: 0.944

aaaacccgctttcgtctgcgggccgtggctggctgg	CRISPR spacer
aaaacccgttttcgtctgcgggccgtgggtggctgg	Protospacer
********.******************* *******

569. spacer 85.4|6253315|31|CP032698|CRT matches to position: 1693781-1693811, mismatch: 2, identity: 0.935

agcccttcggtctgcggaccgtgctcgcttc	CRISPR spacer
agcccttcggtctgcgggccgtggtcgcttc	Protospacer
*****************.***** *******

570. spacer 85.4|6253315|31|CP032698|CRT matches to position: 2482967-2482997, mismatch: 2, identity: 0.935

agcccttcggtctgcggaccgtgctcgcttc	CRISPR spacer
agcccttcggtctgcgggccgtggtcgcttc	Protospacer
*****************.***** *******

571. spacer 85.4|6253315|31|CP032698|CRT matches to position: 2483082-2483112, mismatch: 2, identity: 0.935

agcccttcggtctgcggaccgtgctcgcttc	CRISPR spacer
agcccttcggtctgcgggccgtggtcgcttc	Protospacer
*****************.***** *******

572. spacer 88.1|6739104|47|CP032698|CRISPRCasFinder matches to position: 3662458-3662504, mismatch: 2, identity: 0.957

cgggttcgcccacccacccgcccgtgacgggggttggacagcccggg	CRISPR spacer
cgcgtttgcccacccacccgcccgtgacgggggttggacagcccggg	Protospacer
** ***.****************************************

573. spacer 89.2|6739334|35|CP032698|CRT matches to position: 2474829-2474863, mismatch: 2, identity: 0.943

gaagcgaccacggcccgcaggccgagagcggggtt	CRISPR spacer
gaagcgaccacggcccgcaggccgaaagcgggttt	Protospacer
*************************.****** **

574. spacer 89.2|6739334|35|CP032698|CRT matches to position: 3282387-3282421, mismatch: 2, identity: 0.943

gaagcgaccacggcccgcaggccgagagcggggtt	CRISPR spacer
gaagcgaccacggcccgcaagccgagagcgggttt	Protospacer
*******************.************ **

575. spacer 89.4|6739450|35|CP032698|CRT matches to position: 2474829-2474863, mismatch: 2, identity: 0.943

gaagcgaccacggcccgcaggccgagagcggggtt	CRISPR spacer
gaagcgaccacggcccgcaggccgaaagcgggttt	Protospacer
*************************.****** **

576. spacer 89.4|6739450|35|CP032698|CRT matches to position: 3282387-3282421, mismatch: 2, identity: 0.943

gaagcgaccacggcccgcaggccgagagcggggtt	CRISPR spacer
gaagcgaccacggcccgcaagccgagagcgggttt	Protospacer
*******************.************ **

577. spacer 90.1|6763447|31|CP032698|CRISPRCasFinder matches to position: 3568168-3568198, mismatch: 2, identity: 0.935

aaccctctcgcccctgcggaccgtccccgct	CRISPR spacer
aaccctctcgaccctgcggaccgtgcccgct	Protospacer
********** ************* ******

578. spacer 90.1|6763447|31|CP032698|CRISPRCasFinder matches to position: 3919348-3919378, mismatch: 2, identity: 0.935

aaccctctcgcccctgcggaccgtccccgct	CRISPR spacer
aaccctctcgaccctgcggaccgtgcccgct	Protospacer
********** ************* ******

579. spacer 90.1|6763447|31|CP032698|CRISPRCasFinder matches to position: 4787739-4787769, mismatch: 2, identity: 0.935

aaccctctcgcccctgcggaccgtccccgct	CRISPR spacer
aaccctctcgaccctgcggaccgtgcccgct	Protospacer
********** ************* ******

580. spacer 90.1|6763447|31|CP032698|CRISPRCasFinder matches to position: 4787854-4787884, mismatch: 2, identity: 0.935

aaccctctcgcccctgcggaccgtccccgct	CRISPR spacer
aaccctctcgaccctgcggaccgtgcccgct	Protospacer
********** ************* ******

581. spacer 90.1|6763447|31|CP032698|CRISPRCasFinder matches to position: 5853440-5853470, mismatch: 2, identity: 0.935

aaccctctcgcccctgcggaccgtccccgct	CRISPR spacer
aaccctctcgaccctgcggaccgtgcccgct	Protospacer
********** ************* ******

582. spacer 91.1|6963306|34|CP032698|CRISPRCasFinder matches to position: 1230385-1230418, mismatch: 2, identity: 0.941

cccgtctcgatcctgcgggccgtggtcgcttctc	CRISPR spacer
cccctctcgatcctgcgggccgtgctcgcttctc	Protospacer
*** ******************** *********

583. spacer 95.1|7390256|34|CP032698|PILER-CR matches to position: 5306813-5306846, mismatch: 2, identity: 0.941

ccagccccgcacggtccgcggacgaatgcgggtt	CRISPR spacer
ccagccccgcacggtccgcagacgaaagcgggtt	Protospacer
*******************.****** *******

584. spacer 95.1|7390256|34|CP032698|PILER-CR matches to position: 7574124-7574157, mismatch: 2, identity: 0.941

ccagccccgcacggtccgcggacgaatgcgggtt	CRISPR spacer
ccagccccgcacggtccgcggacgaaaacgggtt	Protospacer
************************** .******

585. spacer 95.3|7390372|34|CP032698|PILER-CR matches to position: 1693722-1693755, mismatch: 2, identity: 0.941

ccagccacgcacggctggcagccgaaaacgggtt	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggtt	Protospacer
***************. *****************

586. spacer 95.3|7390372|34|CP032698|PILER-CR matches to position: 4967576-4967609, mismatch: 2, identity: 0.941

ccagccacgcacggctggcagccgaaaacgggtt	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggtt	Protospacer
***************. *****************

587. spacer 95.3|7390372|34|CP032698|PILER-CR matches to position: 5090838-5090871, mismatch: 2, identity: 0.941

ccagccacgcacggctggcagccgaaaacgggtt	CRISPR spacer
ccagccacgcacggctcgcagacgaaaacgggtt	Protospacer
**************** **** ************

588. spacer 95.3|7390372|34|CP032698|PILER-CR matches to position: 5445818-5445851, mismatch: 2, identity: 0.941

ccagccacgcacggctggcagccgaaaacgggtt	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggtt	Protospacer
***************. *****************

589. spacer 95.7|7390372|37|CP032698|CRT matches to position: 5445818-5445854, mismatch: 2, identity: 0.946

ccagccacgcacggctggcagccgaaaacgggttttc	CRISPR spacer
ccagccacgcacggcccgcagccgaaaacgggttttc	Protospacer
***************. ********************

590. spacer 96.1|7574011|33|CP032698|CRISPRCasFinder matches to position: 6642003-6642035, mismatch: 2, identity: 0.939

ccagccccgcacggtccgcagaccgaagggctt	CRISPR spacer
ccagccacgcacggtccgcggaccgaagggctt	Protospacer
****** ************.*************

591. spacer 96.2|7574068|32|CP032698|CRISPRCasFinder matches to position: 5326274-5326305, mismatch: 2, identity: 0.938

gaagcgaccgcggtccgtaggttcgagagggt	CRISPR spacer
gaagcgaccgcggtccgcaggttcgagcgggt	Protospacer
*****************.********* ****

592. spacer 96.2|7574068|32|CP032698|CRISPRCasFinder matches to position: 5326331-5326362, mismatch: 2, identity: 0.938

gaagcgaccgcggtccgtaggttcgagagggt	CRISPR spacer
gaagcgaccgcggtccgcaggttcgagcgggt	Protospacer
*****************.********* ****

593. spacer 96.2|7574068|32|CP032698|CRISPRCasFinder matches to position: 5326388-5326419, mismatch: 2, identity: 0.938

gaagcgaccgcggtccgtaggttcgagagggt	CRISPR spacer
gaagcgaccgcggtccgcaggttcgagcgggt	Protospacer
*****************.********* ****

594. spacer 96.2|7574068|32|CP032698|CRISPRCasFinder matches to position: 5326445-5326476, mismatch: 2, identity: 0.938

gaagcgaccgcggtccgtaggttcgagagggt	CRISPR spacer
gaagcgaccgcggtccgcaggttcgagcgggt	Protospacer
*****************.********* ****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP032698_14	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	NC_006569	Ruegeria pomeroyi DSS-3 megaplasmid, complete sequence	227752-227771	0	1.0
CP032698_1	1.1|274707|26|CP032698|CRISPRCasFinder	274707-274732	26	NZ_AP022334	Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49b, complete sequence	192744-192769	5	0.808
CP032698_1	1.1|274707|26|CP032698|CRISPRCasFinder	274707-274732	26	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	283710-283735	5	0.808
CP032698_1	1.1|274707|26|CP032698|CRISPRCasFinder	274707-274732	26	NZ_CP022367	Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence	612735-612760	5	0.808
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	MH020235	Mycobacterium phage Batiatus, complete genome	40453-40484	5	0.844
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	FJ174693	Mycobacterium phage Ramsey, complete genome	40744-40775	5	0.844
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	MH825707	Mycobacterium phage MilleniumForce, complete genome	42588-42619	5	0.844
CP032698_8	8.1|2471199|28|CP032698|CRISPRCasFinder	2471199-2471226	28	NZ_CP017565	Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence	172273-172300	6	0.786
CP032698_18	18.1|3355695|29|CP032698|CRISPRCasFinder	3355695-3355723	29	MH067971	Arthrobacter sp. strain ANT_H40 plasmid pA40H2, complete sequence	76208-76236	6	0.793
CP032698_18	18.2|3355751|29|CP032698|CRISPRCasFinder	3355751-3355779	29	NC_015184	Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence	273217-273245	6	0.793
CP032698_18	18.4|3355762|28|CP032698|PILER-CR	3355762-3355789	28	NC_015184	Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence	273217-273244	6	0.786
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	NZ_CP043507	Acetobacter sp. KACC 21233 plasmid unnamed1, complete sequence	15875-15903	6	0.793
CP032698_38	38.2|4133580|30|CP032698|PILER-CR	4133580-4133609	30	NZ_CP020952	Rhizobium sp. CIAT894 plasmid pRheCIAT894e, complete sequence	270351-270380	6	0.8
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	NZ_CP043507	Acetobacter sp. KACC 21233 plasmid unnamed1, complete sequence	15874-15904	6	0.806
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	157393-157423	6	0.806
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	157400-157430	6	0.806
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	157393-157423	6	0.806
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	157400-157430	6	0.806
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	83647-83677	6	0.806
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	83654-83684	6	0.806
CP032698_96	96.1|7574011|33|CP032698|CRISPRCasFinder	7574011-7574043	33	NZ_CP015204	Rhodococcus sp. 008 plasmid pR8C1, complete sequence	40976-41008	6	0.818
CP032698_2	2.4|1292480|32|CP032698|CRISPRCasFinder	1292480-1292511	32	NZ_CP005192	Sphingobium sp. MI1205 plasmid pMI3, complete sequence	73033-73064	7	0.781
CP032698_2	2.4|1292480|32|CP032698|CRISPRCasFinder	1292480-1292511	32	AB244976	Uncultured bacterium plasmid pLB1 DNA, complete sequence	50657-50688	7	0.781
CP032698_8	8.1|2471199|28|CP032698|CRISPRCasFinder	2471199-2471226	28	NC_014120	Paraburkholderia sp. CCGE1002 plasmid pBC201, complete sequence	24971-24998	7	0.75
CP032698_16	16.1|3086539|32|CP032698|CRT	3086539-3086570	32	NZ_LR134467	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence	23627-23658	7	0.781
CP032698_16	16.2|3086607|32|CP032698|CRT	3086607-3086638	32	NZ_CP025548	Mycobacterium paragordonae strain 49061 plasmid unnamed2, complete sequence	114932-114963	7	0.781
CP032698_16	16.2|3086607|32|CP032698|CRT	3086607-3086638	32	NZ_CP025548	Mycobacterium paragordonae strain 49061 plasmid unnamed2, complete sequence	119929-119960	7	0.781
CP032698_18	18.1|3355695|29|CP032698|CRISPRCasFinder	3355695-3355723	29	MH067970	Arthrobacter sp. strain ANT_H40 plasmid pA40H1, complete sequence	55126-55154	7	0.759
CP032698_18	18.1|3355695|29|CP032698|CRISPRCasFinder	3355695-3355723	29	MH067974	Arthrobacter sp. strain ANT_H58 plasmid pA58H1, complete sequence	26364-26392	7	0.759
CP032698_18	18.1|3355695|29|CP032698|CRISPRCasFinder	3355695-3355723	29	MH252365	Ralstonia phage phiRSP, complete genome	26941-26969	7	0.759
CP032698_18	18.2|3355751|29|CP032698|CRISPRCasFinder	3355751-3355779	29	NC_008826	Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence	180779-180807	7	0.759
CP032698_18	18.4|3355762|28|CP032698|PILER-CR	3355762-3355789	28	NC_008826	Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence	180779-180806	7	0.75
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	1202521-1202549	7	0.759
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	986866-986894	7	0.759
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	NZ_CP053565	Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence	16535-16563	7	0.759
CP032698_25	25.2|3679888|29|CP032698|PILER-CR	3679888-3679916	29	NZ_CP029777	Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence	259157-259185	7	0.759
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	NZ_KX443399	Rhodococcus hoagii strain PAM1354 plasmid pVAPA1354, complete sequence	114659-114686	7	0.75
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	NZ_KX443400	Rhodococcus hoagii strain PAM1557 plasmid pVAPN1557, complete sequence	114684-114711	7	0.75
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	NZ_KX443398	Rhodococcus hoagii strain PAM1204 plasmid pVAPN1204, complete sequence	114654-114681	7	0.75
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	NZ_KP851975	Rhodococcus hoagii strain PAM2012 plasmid pVAPN2012, complete sequence	114792-114819	7	0.75
CP032698_35	35.2|4020307|28|CP032698|PILER-CR	4020307-4020334	28	NZ_KF439868	Rhodococcus hoagii strain PAM1571 plasmid pVAPN1571, complete sequence	113799-113826	7	0.75
CP032698_37	37.1|4052075|39|CP032698|CRISPRCasFinder	4052075-4052113	39	NC_016623	Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence	212399-212437	7	0.821
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	293271-293300	7	0.767
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2850118-2850147	7	0.767
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	NZ_CP043507	Acetobacter sp. KACC 21233 plasmid unnamed1, complete sequence	15875-15904	7	0.767
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	360097-360126	7	0.767
CP032698_38	38.2|4133580|30|CP032698|PILER-CR	4133580-4133609	30	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	625871-625900	7	0.767
CP032698_47	47.4|4480898|30|CP032698|CRT	4480898-4480927	30	NZ_CP016313	Thermus brockianus strain GE-1 plasmid pTB1, complete sequence	19120-19149	7	0.767
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	NC_009717	Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence	68756-68785	7	0.767
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	MH823906	Citrobacter phage Maroon, complete genome	114118-114147	7	0.767
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	LC589952	Enterobacter phage vB_EkoM5VN DNA, complete genome	162875-162904	7	0.767
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	KX431560	Cronobacter phage vB_CsaM_leN, complete genome	113961-113990	7	0.767
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	NC_048646	Cronobacter phage vB_CsaM_leE, complete genome	115484-115513	7	0.767
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	MN508621	UNVERIFIED: Enterobacter phage EC-W1, complete genome	129072-129101	7	0.767
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	MT341500	Enterobacter phage EBPL, complete genome	115986-116015	7	0.767
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	KT381880	Citrobacter phage Margaery, complete genome	113703-113732	7	0.767
CP032698_60	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	NC_048645	Cronobacter phage vB_CsaM_leB, complete genome	112909-112938	7	0.767
CP032698_62	62.1|5195978|33|CP032698|CRT	5195978-5196010	33	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	717005-717037	7	0.788
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	NZ_CP010826	Thermus aquaticus Y51MC23 plasmid pTA78, complete sequence	34247-34277	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MK878898	Gordonia phage Zameen, complete genome	38080-38110	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MK919483	Gordonia phage Suscepit, complete genome	38081-38111	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MK284520	Gordonia phage Lilas, complete genome	40462-40492	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MK016492	Gordonia phage Bialota, complete genome	38712-38742	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MK820642	Gordonia phage Polly, complete genome	37523-37553	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	NC_041883	Gordonia phage Attis, complete genome	35213-35243	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MK814755	Gordonia phage Antonio, complete genome	38080-38110	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MK875796	Gordonia phage Tayonia, complete genome	38080-38110	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MK801734	Gordonia phage LordFarquaad, complete genome	35194-35224	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	KU963257	Gordonia phage Kita, complete genome	38089-38119	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	NC_031251	Gordonia phage SoilAssassin, complete genome	35212-35242	7	0.774
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	NC_031097	Gordonia phage Zirinka, complete genome	38700-38730	7	0.774
CP032698_77	77.2|5941644|31|CP032698|PILER-CR	5941644-5941674	31	NC_008712	Paenarthrobacter aurescens TC1 plasmid pTC1, complete sequence	25097-25127	7	0.774
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	1202520-1202550	7	0.774
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NC_008712	Paenarthrobacter aurescens TC1 plasmid pTC1, complete sequence	246942-246973	7	0.781
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NC_009469	Acidiphilium cryptum JF-5 plasmid pACRY03, complete sequence	54914-54945	7	0.781
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NZ_CP021369	Acidovorax carolinensis strain P4 plasmid pACP4.3, complete sequence	21364-21395	7	0.781
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NZ_CP023739	Methylosinus trichosporium OB3b plasmid pOB3b2, complete sequence	9109-9140	7	0.781
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	MH651167	Gordonia phage Angelique, complete genome	2869-2900	7	0.781
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	1202520-1202551	8	0.75
CP032698_9	9.2|2513654|32|CP032698|PILER-CR	2513654-2513685	32	JN698995	Mycobacterium phage Dori, complete genome	1067-1098	8	0.75
CP032698_9	9.2|2513654|32|CP032698|PILER-CR	2513654-2513685	32	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	765977-766008	8	0.75
CP032698_12	12.1|2818688|32|CP032698|CRISPRCasFinder	2818688-2818719	32	NZ_CP015204	Rhodococcus sp. 008 plasmid pR8C1, complete sequence	40977-41008	8	0.75
CP032698_16	16.1|3086539|32|CP032698|CRT	3086539-3086570	32	MH834612	Arthrobacter phage Faja, complete genome	50108-50139	8	0.75
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	NZ_LR134467	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence	23627-23658	8	0.75
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	NZ_CP051471	Rhodobacter sphaeroides strain CH10 plasmid pRspCH10B, complete sequence	71035-71064	8	0.733
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	NZ_CP030274	Rhodobacter sphaeroides 2.4.1 plasmid pB, complete sequence	92503-92532	8	0.733
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	NZ_CP023551	Rhodobacter sp. CZR27 plasmid unnamed3, complete sequence	44286-44315	8	0.733
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	NZ_CP015215	Rhodobacter sphaeroides strain MBTLJ-13 plasmid d, complete sequence	56316-56345	8	0.733
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	CP047034	Rhodobacter sphaeroides strain DSM 158 plasmid pB, complete sequence	20692-20721	8	0.733
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	NZ_CP015291	Rhodobacter sphaeroides strain MBTLJ-20 plasmid c, complete sequence	35037-35066	8	0.733
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	NZ_CP047040	Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pB, complete sequence	20668-20697	8	0.733
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	NC_011962	Rhodobacter sphaeroides KD131 plasmid pRSKD131A, complete sequence	64309-64338	8	0.733
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	NZ_CP017191	Xanthomonas campestris pv. vesicatoria str. 85-10 plasmid p_XCV_1, complete sequence	154819-154848	8	0.733
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	NZ_CP018463	Xanthomonas euvesicatoria strain LMG930 plasmid pLMG930.2, complete sequence	149211-149240	8	0.733
CP032698_35	35.1|4020249|30|CP032698|PILER-CR	4020249-4020278	30	NC_007507	Xanthomonas campestris pv. vesicatoria str. 85-10 plasmid pXCV183, complete sequence	90685-90714	8	0.733
CP032698_38	38.1|4133520|30|CP032698|PILER-CR	4133520-4133549	30	NZ_CP044976	Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B2) plasmid pPBL-H3_B2-1, complete sequence	137840-137869	8	0.733
CP032698_38	38.3|4133520|31|CP032698|CRISPRCasFinder	4133520-4133550	31	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	293275-293305	8	0.742
CP032698_47	47.4|4480898|30|CP032698|CRT	4480898-4480927	30	NC_017805	Deinococcus gobiensis I-0 plasmid P1, complete sequence	363445-363474	8	0.733
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	293271-293301	8	0.742
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	2850117-2850147	8	0.742
CP032698_53	53.1|4844099|31|CP032698|PILER-CR	4844099-4844129	31	MF614628	Sinorhizobium phage phi3LM21, complete genome	12096-12126	8	0.742
CP032698_71	71.3|5489965|34|CP032698|CRT	5489965-5489998	34	NC_020548	Azoarcus sp. KH32C plasmid pAZKH, complete sequence	626073-626106	8	0.765
CP032698_77	77.1|5941588|31|CP032698|PILER-CR	5941588-5941618	31	NC_021347	Rhodococcus phage E3, complete genome	2319-2349	8	0.742
CP032698_77	77.2|5941644|31|CP032698|PILER-CR	5941644-5941674	31	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	2024771-2024801	8	0.742
CP032698_77	77.2|5941644|31|CP032698|PILER-CR	5941644-5941674	31	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	956821-956851	8	0.742
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	986865-986895	8	0.742
CP032698_90	90.1|6763447|31|CP032698|CRISPRCasFinder	6763447-6763477	31	CP054927	Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence	361536-361566	8	0.742
CP032698_90	90.1|6763447|31|CP032698|CRISPRCasFinder	6763447-6763477	31	NC_014918	Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence	170697-170727	8	0.742
CP032698_90	90.1|6763447|31|CP032698|CRISPRCasFinder	6763447-6763477	31	NZ_LR134456	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence	214405-214435	8	0.742
CP032698_91	91.1|6963306|34|CP032698|CRISPRCasFinder	6963306-6963339	34	NZ_CP010990	Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence	115011-115044	8	0.765
CP032698_91	91.1|6963306|34|CP032698|CRISPRCasFinder	6963306-6963339	34	NZ_CP012186	Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence	103351-103384	8	0.765
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NZ_CP012183	Pseudonocardia sp. EC080610-09 plasmid pBCI2-2, complete sequence	6953-6984	8	0.75
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NZ_LN606601	Acetobacter senegalensis strain 108B plasmid 1P, complete sequence	60360-60391	8	0.75
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5411153-5411183	8	0.742
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NC_024971	Streptomyces rochei plasmid pSLA2-S DNA, complete sequence, strain: 7434AN4	200-230	8	0.742
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NC_024971	Streptomyces rochei plasmid pSLA2-S DNA, complete sequence, strain: 7434AN4	17297-17327	8	0.742
CP032698_95	95.8|7390431|34|CP032698|CRT	7390431-7390464	34	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	157393-157426	8	0.765
CP032698_95	95.8|7390431|34|CP032698|CRT	7390431-7390464	34	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	157393-157426	8	0.765
CP032698_95	95.8|7390431|34|CP032698|CRT	7390431-7390464	34	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	83647-83680	8	0.765
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	986865-986896	9	0.719
CP032698_2	2.5|1292536|32|CP032698|CRISPRCasFinder	1292536-1292567	32	NZ_CP053565	Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence	16534-16565	9	0.719
CP032698_10	10.2|2628756|33|CP032698|PILER-CR	2628756-2628788	33	AP014720	Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8	158295-158327	9	0.727
CP032698_10	10.3|2628812|35|CP032698|PILER-CR	2628812-2628846	35	NZ_CP047174	Rathayibacter sp. VKM Ac-2760 plasmid unnamed1, complete sequence	79864-79898	9	0.743
CP032698_16	16.1|3086539|32|CP032698|CRT	3086539-3086570	32	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	700658-700689	9	0.719
CP032698_16	16.1|3086539|32|CP032698|CRT	3086539-3086570	32	MH020235	Mycobacterium phage Batiatus, complete genome	40453-40484	9	0.719
CP032698_16	16.1|3086539|32|CP032698|CRT	3086539-3086570	32	FJ174693	Mycobacterium phage Ramsey, complete genome	40744-40775	9	0.719
CP032698_16	16.1|3086539|32|CP032698|CRT	3086539-3086570	32	MH825707	Mycobacterium phage MilleniumForce, complete genome	42588-42619	9	0.719
CP032698_20	20.1|3444592|34|CP032698|CRISPRCasFinder	3444592-3444625	34	NC_029033	Achromobacter phage phiAxp-1, complete genome	11157-11190	9	0.735
CP032698_45	45.1|4439171|33|CP032698|CRISPRCasFinder	4439171-4439203	33	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	293272-293304	9	0.727
CP032698_57	57.1|4918292|33|CP032698|CRISPRCasFinder	4918292-4918324	33	NZ_CP046723	Pantoea agglomerans strain ASB05 plasmid pASB05p1, complete sequence	432079-432111	9	0.727
CP032698_57	57.1|4918292|33|CP032698|CRISPRCasFinder	4918292-4918324	33	NZ_CP034470	Pantoea agglomerans strain CFSAN047153 plasmid pCFSAN047153_1, complete sequence	608659-608691	9	0.727
CP032698_57	57.1|4918292|33|CP032698|CRISPRCasFinder	4918292-4918324	33	NZ_CP034149	Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence	411981-412013	9	0.727
CP032698_57	57.1|4918292|33|CP032698|CRISPRCasFinder	4918292-4918324	33	NZ_CP034475	Pantoea agglomerans strain CFSAN047154 plasmid pCFSAN047154_1, complete sequence	198086-198118	9	0.727
CP032698_58	58.2|5049229|32|CP032698|PILER-CR,CRT	5049229-5049260	32	NC_008269	Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence	440706-440737	9	0.719
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	NZ_CP018784	Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence	476204-476235	9	0.719
CP032698_62	62.1|5195978|33|CP032698|CRT	5195978-5196010	33	NZ_CP029340	Streptomyces sp. SM17 plasmid pSM17B, complete sequence	5460-5492	9	0.727
CP032698_62	62.1|5195978|33|CP032698|CRT	5195978-5196010	33	NZ_CP029340	Streptomyces sp. SM17 plasmid pSM17B, complete sequence	20155-20187	9	0.727
CP032698_63	63.1|5243534|33|CP032698|CRISPRCasFinder	5243534-5243566	33	NZ_CP015882	Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence	723980-724012	9	0.727
CP032698_63	63.1|5243534|33|CP032698|CRISPRCasFinder	5243534-5243566	33	NZ_CP030264	Ensifer adhaerens strain Corn53 plasmid AB, complete sequence	182043-182075	9	0.727
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	AP014693	Ralstonia phage RSL2 DNA, complete sequence	122052-122082	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	KT281796	Mycobacterium phage Zakhe101, complete genome	5728-5758	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	AY129335	Mycobacterium virus Corndog, complete genome	5836-5866	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MN428058	Mycobacterium phage Krili, complete genome	5490-5520	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MH020246	Mycobacterium phage SchoolBus, complete genome	5162-5192	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MT818418	Mycobacterium phage Shida, complete genome	5416-5446	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	NC_004685	Mycobacterium phage Corndog, complete genome	5836-5866	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	JN698993	Mycobacterium phage Firecracker, complete genome	5457-5487	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MH926062	Mycobacterium phage Vorrps, complete genome	5350-5380	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MG099943	Mycobacterium phage Familton, complete genome	5162-5192	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MG872838	Mycobacterium phage JangDynasty, complete genome	5251-5281	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MH590592	Mycobacterium phage Ryadel, complete genome	5944-5974	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MN585964	Mycobacterium phage Blessica, complete genome	5121-5151	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	KJ829260	Mycobacterium phage YungJamal, complete genome	5716-5746	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	NC_022057	Mycobacterium phage Catdawg, complete genome	5161-5191	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MT818425	Mycobacterium phage NiebruSaylor, complete genome	5350-5380	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	NC_022325	Mycobacterium phage Dylan, complete genome	5724-5754	9	0.71
CP032698_65	65.1|5406027|31|CP032698|CRISPRCasFinder	5406027-5406057	31	MN428052	Mycobacterium phage Smooch, complete genome	5680-5710	9	0.71
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	MT498057	Microbacterium phage Cicada, complete genome	40376-40407	9	0.719
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	MK016497	Microbacterium phage Johann, complete genome	40389-40420	9	0.719
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	MK016495	Microbacterium phage Goodman, complete genome	40389-40420	9	0.719
CP032698_71	71.1|5489850|34|CP032698|CRT	5489850-5489883	34	NZ_CP054620	Azospirillum oryzae strain KACC 14407 plasmid unnamed5, complete sequence	421011-421044	9	0.735
CP032698_77	77.2|5941644|31|CP032698|PILER-CR	5941644-5941674	31	NZ_CP032685	Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence	384386-384416	9	0.71
CP032698_77	77.2|5941644|31|CP032698|PILER-CR	5941644-5941674	31	NZ_CP032690	Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence	384384-384414	9	0.71
CP032698_77	77.3|5941700|32|CP032698|PILER-CR	5941700-5941731	32	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	950026-950057	9	0.719
CP032698_81	81.1|6018757|32|CP032698|PILER-CR	6018757-6018788	32	NC_015184	Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence	273222-273253	9	0.719
CP032698_85	85.2|6253198|31|CP032698|CRT	6253198-6253228	31	NZ_CP053565	Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence	16534-16564	9	0.71
CP032698_85	85.4|6253315|31|CP032698|CRT	6253315-6253345	31	NZ_CP015204	Rhodococcus sp. 008 plasmid pR8C1, complete sequence	40977-41007	9	0.71
CP032698_90	90.1|6763447|31|CP032698|CRISPRCasFinder	6763447-6763477	31	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	343309-343339	9	0.71
CP032698_95	95.1|7390256|34|CP032698|PILER-CR	7390256-7390289	34	NC_002679	Mesorhizobium japonicum MAFF 303099 plasmid pMLa, complete sequence	78180-78213	9	0.735
CP032698_95	95.1|7390256|34|CP032698|PILER-CR	7390256-7390289	34	NZ_CP012477	Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence	117258-117291	9	0.735
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	394048-394079	9	0.719
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1419019-1419050	9	0.719
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	319673-319704	9	0.719
CP032698_95	95.3|7390372|34|CP032698|PILER-CR	7390372-7390405	34	NZ_LN907828	Erwinia gerundensis isolate E_g_EM595 plasmid pEM01, complete sequence	66477-66510	9	0.735
CP032698_95	95.3|7390372|34|CP032698|PILER-CR	7390372-7390405	34	NZ_CP010421	Azotobacter chroococcum NCIMB 8003 plasmid pAcX50f, complete sequence	256764-256797	9	0.735
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NC_015952	Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence	40899-40929	9	0.71
CP032698_95	95.4|7390431|31|CP032698|PILER-CR	7390431-7390461	31	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	396686-396716	9	0.71
CP032698_95	95.6|7390315|35|CP032698|CRT	7390315-7390349	35	NC_008712	Paenarthrobacter aurescens TC1 plasmid pTC1, complete sequence	246942-246976	9	0.743
CP032698_10	10.2|2628756|33|CP032698|PILER-CR	2628756-2628788	33	NC_012586	Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence	2049917-2049949	10	0.697
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	NZ_CP025015	Rhizobium leguminosarum strain Norway plasmid pRLN3, complete sequence	217994-218025	10	0.688
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	NZ_CP025015	Rhizobium leguminosarum strain Norway plasmid pRLN3, complete sequence	437317-437348	10	0.688
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	NZ_CP049734	Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence	104116-104147	10	0.688
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	NZ_CP025505	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvC, complete sequence	112497-112528	10	0.688
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	CP049734	Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence	221355-221386	10	0.688
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	NZ_CP054024	Rhizobium sp. JKLM12A2 plasmid pPR12A203, complete sequence	104885-104916	10	0.688
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	NZ_CP022669	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR4, complete sequence	231046-231077	10	0.688
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	NZ_CP054035	Rhizobium sp. JKLM13E plasmid pPR13E04, complete sequence	72134-72165	10	0.688
CP032698_16	16.3|3086675|32|CP032698|CRT	3086675-3086706	32	NZ_CP050090	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b4, complete sequence	93541-93572	10	0.688
CP032698_21	21.1|3487093|34|CP032698|CRISPRCasFinder	3487093-3487126	34	NC_006674	Gluconobacter oxydans 621H plasmid pGOX3, complete sequence	11227-11260	10	0.706
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	NZ_CP013419	Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence	47099-47131	10	0.697
CP032698_26	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	NZ_CP013415	Burkholderia ubonensis strain MSMB2035 plasmid pMSMB2035, complete sequence	224601-224633	10	0.697
CP032698_42	42.2|4174702|34|CP032698|CRT	4174702-4174735	34	CP042595	Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence	194148-194181	10	0.706
CP032698_42	42.4|4174703|34|CP032698|PILER-CR	4174703-4174736	34	CP042595	Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence	194148-194181	10	0.706
CP032698_47	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	NZ_CP015743	Shinella sp. HZN7 plasmid pShin-07, complete sequence	124509-124540	10	0.688
CP032698_59	59.3|5075332|32|CP032698|CRISPRCasFinder	5075332-5075363	32	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5485730-5485761	10	0.688
CP032698_62	62.1|5195978|33|CP032698|CRT	5195978-5196010	33	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	518616-518648	10	0.697
CP032698_70	70.2|5488625|32|CP032698|PILER-CR	5488625-5488656	32	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	565605-565636	10	0.688
CP032698_71	71.1|5489850|34|CP032698|CRT	5489850-5489883	34	NZ_CP021029	Rhizobium sp. TAL182 plasmid pRetTAL182e, complete sequence	170475-170508	10	0.706
CP032698_91	91.1|6963306|34|CP032698|CRISPRCasFinder	6963306-6963339	34	MT740745	Ralstonia phage Raharianne, complete genome	27668-27701	10	0.706
CP032698_91	91.1|6963306|34|CP032698|CRISPRCasFinder	6963306-6963339	34	MT740726	Ralstonia phage Albius, complete genome	27730-27763	10	0.706
CP032698_91	91.1|6963306|34|CP032698|CRISPRCasFinder	6963306-6963339	34	MT740743	Ralstonia phage Hyacinthe, complete genome	19128-19161	10	0.706
CP032698_95	95.1|7390256|34|CP032698|PILER-CR	7390256-7390289	34	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	382635-382668	10	0.706
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NZ_CP010727	Phaeobacter inhibens strain P88 plasmid pP88_b, complete sequence	61255-61286	10	0.688
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NC_009955	Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI01, complete sequence	38951-38982	10	0.688
CP032698_95	95.2|7390315|32|CP032698|PILER-CR	7390315-7390346	32	NZ_CP021115	Rhodobacteraceae bacterium strain G7 plasmid unnamed1, complete sequence	59408-59439	10	0.688
CP032698_95	95.6|7390315|35|CP032698|CRT	7390315-7390349	35	NC_009469	Acidiphilium cryptum JF-5 plasmid pACRY03, complete sequence	54914-54948	10	0.714
CP032698_34	34.4|4013847|36|CP032698|CRT	4013847-4013882	36	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	629751-629786	11	0.694
CP032698_55	55.2|4866532|34|CP032698|PILER-CR	4866532-4866565	34	NZ_CP023451	Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p2, complete sequence	219934-219967	11	0.676
CP032698_55	55.2|4866532|34|CP032698|PILER-CR	4866532-4866565	34	NZ_AP018666	Sphingobium amiense strain DSM 16289 plasmid pSAMIE_3, complete sequence	37546-37579	11	0.676
CP032698_55	55.2|4866532|34|CP032698|PILER-CR	4866532-4866565	34	CP021185	Sphingomonas wittichii DC-6 plasmid pDC04, complete sequence	44731-44764	11	0.676
CP032698_55	55.2|4866532|34|CP032698|PILER-CR	4866532-4866565	34	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	518615-518648	11	0.676
CP032698_59	59.1|5075217|32|CP032698|CRISPRCasFinder	5075217-5075248	32	MN694483	Marine virus AFVG_250M1031, complete genome	1045-1076	11	0.656
CP032698_71	71.3|5489965|34|CP032698|CRT	5489965-5489998	34	NZ_CP024427	Paracoccus yeei strain TT13 plasmid pTT13-5, complete sequence	957-990	11	0.676
CP032698_71	71.3|5489965|34|CP032698|CRT	5489965-5489998	34	NZ_CP020443	Paracoccus yeei strain FDAARGOS_252 plasmid unnamed3, complete sequence	125403-125436	11	0.676
CP032698_95	95.3|7390372|34|CP032698|PILER-CR	7390372-7390405	34	NZ_CP013419	Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence	47099-47132	11	0.676
CP032698_95	95.3|7390372|34|CP032698|PILER-CR	7390372-7390405	34	NZ_CP013415	Burkholderia ubonensis strain MSMB2035 plasmid pMSMB2035, complete sequence	224600-224633	11	0.676
CP032698_95	95.6|7390315|35|CP032698|CRT	7390315-7390349	35	NZ_CP012183	Pseudonocardia sp. EC080610-09 plasmid pBCI2-2, complete sequence	6950-6984	11	0.686
CP032698_95	95.8|7390431|34|CP032698|CRT	7390431-7390464	34	NC_024970	Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence	157397-157430	11	0.676
CP032698_95	95.8|7390431|34|CP032698|CRT	7390431-7390464	34	NZ_KJ396772	Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence	157397-157430	11	0.676
CP032698_95	95.8|7390431|34|CP032698|CRT	7390431-7390464	34	NZ_CP024986	Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence	83651-83684	11	0.676
CP032698_95	95.5|7390256|37|CP032698|CRT	7390256-7390292	37	NC_023284	Streptomyces sp. F2 plasmid pFRL4, complete sequence	382632-382668	13	0.649

1. spacer 14.2|2936098|20|CP032698|PILER-CR matches to NC_006569 (Ruegeria pomeroyi DSS-3 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccccgacccgcac	Protospacer
********************

2. spacer 1.1|274707|26|CP032698|CRISPRCasFinder matches to NZ_AP022334 (Methylosinus sp. C49 isolate Methylosinus sp. C49 plasmid pMSC49b, complete sequence) position: , mismatch: 5, identity: 0.808

tgcggggcggtcgccggacagacgac	CRISPR spacer
cgcggggcgatcgccggactgacgga	Protospacer
.********.********* ****. 

3. spacer 1.1|274707|26|CP032698|CRISPRCasFinder matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 5, identity: 0.808

tgcggggcggtcgccggacagacgac	CRISPR spacer
cccggggcggtcgccggcccgacgag	Protospacer
. *************** * ***** 

4. spacer 1.1|274707|26|CP032698|CRISPRCasFinder matches to NZ_CP022367 (Azospirillum sp. TSH58 plasmid TSH58_p02, complete sequence) position: , mismatch: 5, identity: 0.808

tgcggggcggtcgccggacagacgac	CRISPR spacer
ggcggggcggttgccggacagaagga	Protospacer
 **********.********** *. 

5. spacer 16.3|3086675|32|CP032698|CRT matches to MH020235 (Mycobacterium phage Batiatus, complete genome) position: , mismatch: 5, identity: 0.844

accgacggcccgcacccgaacaaccg-gcacgc	CRISPR spacer
accgtcagcccgcacccgaacaactgtgcgcg-	Protospacer
**** *.*****************.* **.** 

6. spacer 16.3|3086675|32|CP032698|CRT matches to FJ174693 (Mycobacterium phage Ramsey, complete genome) position: , mismatch: 5, identity: 0.844

accgacggcccgcacccgaacaaccg-gcacgc	CRISPR spacer
accgtcagcccgcacccgaacaactgtgcgcg-	Protospacer
**** *.*****************.* **.** 

7. spacer 16.3|3086675|32|CP032698|CRT matches to MH825707 (Mycobacterium phage MilleniumForce, complete genome) position: , mismatch: 5, identity: 0.844

accgacggcccgcacccgaacaaccg-gcacgc	CRISPR spacer
accgtcagcccgcacccgaacaactgtgcgcg-	Protospacer
**** *.*****************.* **.** 

8. spacer 8.1|2471199|28|CP032698|CRISPRCasFinder matches to NZ_CP017565 (Paraburkholderia sprentiae WSM5005 plasmid pl2WSM5005, complete sequence) position: , mismatch: 6, identity: 0.786

ccacggcccgcagacgaaaacgggtttg	CRISPR spacer
gtccagcccgcagtagaaaacgggtttg	Protospacer
 . *.********  *************

9. spacer 18.1|3355695|29|CP032698|CRISPRCasFinder matches to MH067971 (Arthrobacter sp. strain ANT_H40 plasmid pA40H2, complete sequence) position: , mismatch: 6, identity: 0.793

ccagccacgcacggtgtgaggccgaaagg	CRISPR spacer
gcagccaggcacggcgtgaggccgaagac	Protospacer
 ****** ******.***********.. 

10. spacer 18.2|3355751|29|CP032698|CRISPRCasFinder matches to NC_015184 (Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence) position: , mismatch: 6, identity: 0.793

gacgcgggcacggtccgcacacgaaggcg	CRISPR spacer
agcatgggcacggtccgcacaggaagccg	Protospacer
..*..**************** **** **

11. spacer 18.4|3355762|28|CP032698|PILER-CR matches to NC_015184 (Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence) position: , mismatch: 6, identity: 0.786

gacgcgggcacggtccgcacacgaaggc	CRISPR spacer
agcatgggcacggtccgcacaggaagcc	Protospacer
..*..**************** **** *

12. spacer 25.2|3679888|29|CP032698|PILER-CR matches to NZ_CP043507 (Acetobacter sp. KACC 21233 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
gctgctgaccctgcggaccgtgcccgcgg	Protospacer
 ** ..*********************  

13. spacer 38.2|4133580|30|CP032698|PILER-CR matches to NZ_CP020952 (Rhizobium sp. CIAT894 plasmid pRheCIAT894e, complete sequence) position: , mismatch: 6, identity: 0.8

ccacctgcgggccgcagacgaaaacaggtt	CRISPR spacer
ccggctttgggccgcagacgaaaaaaggta	Protospacer
**. ** .**************** **** 

14. spacer 85.2|6253198|31|CP032698|CRT matches to NZ_CP043507 (Acetobacter sp. KACC 21233 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.806

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
cgctgctgaccctgcggaccgtgcccgcggg	Protospacer
* ** ..**********************  

15. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 6, identity: 0.806

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
ggagggggcacgggccgcatgcggcccgtgc	Protospacer
*.** ************** ****** * * 

16. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 6, identity: 0.806

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
ggagggggcacgggccgcatgcggcccgtgc	Protospacer
*.** ************** ****** * * 

17. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 6, identity: 0.806

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
ggagggggcacgggccgcatgcggcccgtgc	Protospacer
*.** ************** ****** * * 

18. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 6, identity: 0.806

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
ggagggggcacgggccgcatgcggcccgtgc	Protospacer
*.** ************** ****** * * 

19. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 6, identity: 0.806

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
ggagggggcacgggccgcatgcggcccgtgc	Protospacer
*.** ************** ****** * * 

20. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 6, identity: 0.806

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
ggagggggcacgggccgcatgcggcccgtgc	Protospacer
*.** ************** ****** * * 

21. spacer 96.1|7574011|33|CP032698|CRISPRCasFinder matches to NZ_CP015204 (Rhodococcus sp. 008 plasmid pR8C1, complete sequence) position: , mismatch: 6, identity: 0.818

ccagccc-cgcacggtccgcagaccgaagggctt	CRISPR spacer
-gagcctgcgcacggtccgcagaccgcacggcct	Protospacer
  ****. ****************** * ***.*

22. spacer 2.4|1292480|32|CP032698|CRISPRCasFinder matches to NZ_CP005192 (Sphingobium sp. MI1205 plasmid pMI3, complete sequence) position: , mismatch: 7, identity: 0.781

gaaccgaccacggcccgcagacgaaagcgggg	CRISPR spacer
gaaccgaccaccgccctcagacgggcgcgaga	Protospacer
*********** **** ******.. ***.*.

23. spacer 2.4|1292480|32|CP032698|CRISPRCasFinder matches to AB244976 (Uncultured bacterium plasmid pLB1 DNA, complete sequence) position: , mismatch: 7, identity: 0.781

gaaccgaccacggcccgcagacgaaagcgggg	CRISPR spacer
gaaccgaccaccgccctcagacgggcgcgaga	Protospacer
*********** **** ******.. ***.*.

24. spacer 8.1|2471199|28|CP032698|CRISPRCasFinder matches to NC_014120 (Paraburkholderia sp. CCGE1002 plasmid pBC201, complete sequence) position: , mismatch: 7, identity: 0.75

ccacggcccgcagacgaaaacgggtttg	CRISPR spacer
ttttagcccgcagtagaaaacgggtttg	Protospacer
.. ..********  *************

25. spacer 16.1|3086539|32|CP032698|CRT matches to NZ_LR134467 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence) position: , mismatch: 7, identity: 0.781

cccgacagcccgcacccgaccaaccgacaggc--	CRISPR spacer
gccgacggcctgcacccgaccaacc--tgggccg	Protospacer
 *****.***.**************  ..***  

26. spacer 16.2|3086607|32|CP032698|CRT matches to NZ_CP025548 (Mycobacterium paragordonae strain 49061 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

gtcggcagc-ccgcggacaaccacacaccgcca	CRISPR spacer
-ccaccaccgccgcgcacaaccacaccccgcca	Protospacer
 .*. ** * ***** ********** ******

27. spacer 16.2|3086607|32|CP032698|CRT matches to NZ_CP025548 (Mycobacterium paragordonae strain 49061 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.781

gtcggcagc-ccgcggacaaccacacaccgcca	CRISPR spacer
-ccaccaccgccgcgcacaaccacaccccgcca	Protospacer
 .*. ** * ***** ********** ******

28. spacer 18.1|3355695|29|CP032698|CRISPRCasFinder matches to MH067970 (Arthrobacter sp. strain ANT_H40 plasmid pA40H1, complete sequence) position: , mismatch: 7, identity: 0.759

ccagccacgcacggtgtgaggccgaaagg	CRISPR spacer
gcagccaggcacggcgtgaggccgaggac	Protospacer
 ****** ******.**********... 

29. spacer 18.1|3355695|29|CP032698|CRISPRCasFinder matches to MH067974 (Arthrobacter sp. strain ANT_H58 plasmid pA58H1, complete sequence) position: , mismatch: 7, identity: 0.759

ccagccacgcacggtgtgaggccgaaagg	CRISPR spacer
gcagccaggcacggcgtgaggccgaggac	Protospacer
 ****** ******.**********... 

30. spacer 18.1|3355695|29|CP032698|CRISPRCasFinder matches to MH252365 (Ralstonia phage phiRSP, complete genome) position: , mismatch: 7, identity: 0.759

ccagccacgcacggtgtgaggccgaaagg	CRISPR spacer
cggtccacgcgcggtttgaggccgaaatc	Protospacer
* . ******.**** ***********  

31. spacer 18.2|3355751|29|CP032698|CRISPRCasFinder matches to NC_008826 (Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence) position: , mismatch: 7, identity: 0.759

gacgcgggcacggtccgcacacgaaggcg	CRISPR spacer
ttcgcgcgcacggtcggcacacgaaacag	Protospacer
  **** ******** *********.  *

32. spacer 18.4|3355762|28|CP032698|PILER-CR matches to NC_008826 (Methylibium petroleiphilum PM1 plasmid RPME01, complete sequence) position: , mismatch: 7, identity: 0.75

gacgcgggcacggtccgcacacgaaggc	CRISPR spacer
ttcgcgcgcacggtcggcacacgaaaca	Protospacer
  **** ******** *********.  

33. spacer 25.2|3679888|29|CP032698|PILER-CR matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.759

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cgcatcgaccgtgcggacggtgcccgcga	Protospacer
* . ****** ******* ********  

34. spacer 25.2|3679888|29|CP032698|PILER-CR matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 7, identity: 0.759

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
gccgtcgacccggccgaccgtgcccgcga	Protospacer
 *. ******* ** ************  

35. spacer 25.2|3679888|29|CP032698|PILER-CR matches to NZ_CP053565 (Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
cgactcgaccccgctgaccgtgcccgtcc	Protospacer
*  ********.** ***********...

36. spacer 25.2|3679888|29|CP032698|PILER-CR matches to NZ_CP029777 (Deinococcus actinosclerus strain Deinococcus actinosclerus SJTR plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.759

cctctcgaccctgcggaccgtgcccgctt	CRISPR spacer
ctgccggacccggcggaccgtgcccgccc	Protospacer
*. *. ***** ***************..

37. spacer 35.2|4020307|28|CP032698|PILER-CR matches to NZ_KX443399 (Rhodococcus hoagii strain PAM1354 plasmid pVAPA1354, complete sequence) position: , mismatch: 7, identity: 0.75

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
cctgcggtccgcaggttcgggcggggtg	Protospacer
  ..***************.* ***** 

38. spacer 35.2|4020307|28|CP032698|PILER-CR matches to NZ_KX443400 (Rhodococcus hoagii strain PAM1557 plasmid pVAPN1557, complete sequence) position: , mismatch: 7, identity: 0.75

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
cctgcggtccgcaggttcgggcggggtg	Protospacer
  ..***************.* ***** 

39. spacer 35.2|4020307|28|CP032698|PILER-CR matches to NZ_KX443398 (Rhodococcus hoagii strain PAM1204 plasmid pVAPN1204, complete sequence) position: , mismatch: 7, identity: 0.75

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
cctgcggtccgcaggttcgggcggggtg	Protospacer
  ..***************.* ***** 

40. spacer 35.2|4020307|28|CP032698|PILER-CR matches to NZ_KP851975 (Rhodococcus hoagii strain PAM2012 plasmid pVAPN2012, complete sequence) position: , mismatch: 7, identity: 0.75

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
cctgcggtccgcaggttcgggcggggtg	Protospacer
  ..***************.* ***** 

41. spacer 35.2|4020307|28|CP032698|PILER-CR matches to NZ_KF439868 (Rhodococcus hoagii strain PAM1571 plasmid pVAPN1571, complete sequence) position: , mismatch: 7, identity: 0.75

ggcacggtccgcaggttcgagaggggtt	CRISPR spacer
cctgcggtccgcaggttcgggcggggtg	Protospacer
  ..***************.* ***** 

42. spacer 37.1|4052075|39|CP032698|CRISPRCasFinder matches to NC_016623 (Azospirillum lipoferum 4B plasmid AZO_p3, complete sequence) position: , mismatch: 7, identity: 0.821

cccgcgccggcggtacgggcacccccggacgggcgccac-	CRISPR spacer
gcggcgccggcggtacgggcagcaccggacggg-gtaacc	Protospacer
 * ****************** * ********* *. ** 

43. spacer 38.1|4133520|30|CP032698|PILER-CR matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 7, identity: 0.767

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
aagtcgggcacggtccgcatgatcgacgga	Protospacer
.*  *************** ****** .*.

44. spacer 38.1|4133520|30|CP032698|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.767

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gtcgcgggcacggtccgctggaccgacccc	Protospacer
* **************** ***.***    

45. spacer 38.1|4133520|30|CP032698|PILER-CR matches to NZ_CP043507 (Acetobacter sp. KACC 21233 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
cccgcgggcacggtccgcagggtcagcagc	Protospacer
  *******************.**.. ** 

46. spacer 38.1|4133520|30|CP032698|PILER-CR matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
gccgcgggcccggtccgccggatcggtgga	Protospacer
* ******* ******** ******. .*.

47. spacer 38.2|4133580|30|CP032698|PILER-CR matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

ccacctgcgggccgcagacgaaaacaggtt	CRISPR spacer
gcgacggcgggccgcagacggaaaccggtc	Protospacer
 *. * **************.**** ***.

48. spacer 47.4|4480898|30|CP032698|CRT matches to NZ_CP016313 (Thermus brockianus strain GE-1 plasmid pTB1, complete sequence) position: , mismatch: 7, identity: 0.767

aaaagtgggcccggttcgtggtggcggggg	CRISPR spacer
tcgccggggcccggttcgtggtggaggggg	Protospacer
  .   ****************** *****

49. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to NC_009717 (Xanthobacter autotrophicus Py2 plasmid pXAUT01, complete sequence) position: , mismatch: 7, identity: 0.767

acccgctttcgggtgcgggccgtggtcgct	CRISPR spacer
cggcgcttccgggtgctggccgtggtcgac	Protospacer
   *****.******* *********** .

50. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to MH823906 (Citrobacter phage Maroon, complete genome) position: , mismatch: 7, identity: 0.767

acccgctttcgggtgcgggccgtg-gtcgct	CRISPR spacer
tcccgctttcgggtgcgggtcgtacaatgc-	Protospacer
 ******************.***. . .** 

51. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to LC589952 (Enterobacter phage vB_EkoM5VN DNA, complete genome) position: , mismatch: 7, identity: 0.767

acccgctttcgggtgcgggccgtg-gtcgct	CRISPR spacer
tcccgctttcgggtgcgggtcgtacaatgc-	Protospacer
 ******************.***. . .** 

52. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to KX431560 (Cronobacter phage vB_CsaM_leN, complete genome) position: , mismatch: 7, identity: 0.767

acccgctttcgggtgcgggccgtg-gtcgct	CRISPR spacer
tcccgctttcgggtgcgggtcgtacaatgc-	Protospacer
 ******************.***. . .** 

53. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to NC_048646 (Cronobacter phage vB_CsaM_leE, complete genome) position: , mismatch: 7, identity: 0.767

acccgctttcgggtgcgggccgtg-gtcgct	CRISPR spacer
tcccgctttcgggtgcgggtcgtacaatgc-	Protospacer
 ******************.***. . .** 

54. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to MN508621 (UNVERIFIED: Enterobacter phage EC-W1, complete genome) position: , mismatch: 7, identity: 0.767

acccgctttcgggtgcgggccgtg-gtcgct	CRISPR spacer
tcccgctttcgggtgcgggtcgtacaatgc-	Protospacer
 ******************.***. . .** 

55. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to MT341500 (Enterobacter phage EBPL, complete genome) position: , mismatch: 7, identity: 0.767

acccgctttcgggtgcgggccgtg-gtcgct	CRISPR spacer
tcccgctttcgggtgcgggtcgtacaatgc-	Protospacer
 ******************.***. . .** 

56. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to KT381880 (Citrobacter phage Margaery, complete genome) position: , mismatch: 7, identity: 0.767

acccgctttcgggtgcgggccgtg-gtcgct	CRISPR spacer
tcccgctttcgggtgcgggtcgtacaatgc-	Protospacer
 ******************.***. . .** 

57. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to NC_048645 (Cronobacter phage vB_CsaM_leB, complete genome) position: , mismatch: 7, identity: 0.767

acccgctttcgggtgcgggccgtg-gtcgct	CRISPR spacer
tcccgctttcgggtgcgggtcgtacaatgc-	Protospacer
 ******************.***. . .** 

58. spacer 62.1|5195978|33|CP032698|CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.788

ccctgccccgtccggccccgcgccggttctgcc	CRISPR spacer
cggtgcctcgtccggcccggcgccggtccggac	Protospacer
*  ****.********** ********.* * *

59. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to NZ_CP010826 (Thermus aquaticus Y51MC23 plasmid pTA78, complete sequence) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacggcctccatcctgcgggccgtggccgag	Protospacer
 **  **** ****************.**  

60. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MK878898 (Gordonia phage Zameen, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

61. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MK919483 (Gordonia phage Suscepit, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

62. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MK284520 (Gordonia phage Lilas, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

63. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MK016492 (Gordonia phage Bialota, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

64. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MK820642 (Gordonia phage Polly, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

65. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to NC_041883 (Gordonia phage Attis, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

66. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MK814755 (Gordonia phage Antonio, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

67. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MK875796 (Gordonia phage Tayonia, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

68. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MK801734 (Gordonia phage LordFarquaad, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

69. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to KU963257 (Gordonia phage Kita, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

70. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to NC_031251 (Gordonia phage SoilAssassin, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

71. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to NC_031097 (Gordonia phage Zirinka, complete genome) position: , mismatch: 7, identity: 0.774

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cacccgctcgatcctgcgggccgcctgggct	Protospacer
 **** *****************.    ***

72. spacer 77.2|5941644|31|CP032698|PILER-CR matches to NC_008712 (Paenarthrobacter aurescens TC1 plasmid pTC1, complete sequence) position: , mismatch: 7, identity: 0.774

cccccggtcatgtgcgggccgtggtcgtttt	CRISPR spacer
tgcccggtcatgggcgggccgtcgtggatct	Protospacer
. ********** ********* ** * *.*

73. spacer 85.2|6253198|31|CP032698|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 7, identity: 0.774

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
ccgcatcgaccgtgcggacggtgcccgcgag	Protospacer
** . ****** ******* *********  

74. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NC_008712 (Paenarthrobacter aurescens TC1 plasmid pTC1, complete sequence) position: , mismatch: 7, identity: 0.781

gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
ggcccgggcagggcccgcacccggccgtggtg	Protospacer
*.  ****** **************** **..

75. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NC_009469 (Acidiphilium cryptum JF-5 plasmid pACRY03, complete sequence) position: , mismatch: 7, identity: 0.781

gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
aagacgggcacggcccgctcccgcccgaggat	Protospacer
.*..************** **** ******  

76. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NZ_CP021369 (Acidovorax carolinensis strain P4 plasmid pACP4.3, complete sequence) position: , mismatch: 7, identity: 0.781

-gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
cggtgc-ggcatggccagcacccggccgaggtc	Protospacer
 *. ** ****.**** **************. 

77. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NZ_CP023739 (Methylosinus trichosporium OB3b plasmid pOB3b2, complete sequence) position: , mismatch: 7, identity: 0.781

gaagcg-ggcacggcccgcacccggccgaggca	CRISPR spacer
-aggcgcggctcggcccgcagccggccgagcag	Protospacer
 *.*** *** ********* *********  .

78. spacer 95.2|7390315|32|CP032698|PILER-CR matches to MH651167 (Gordonia phage Angelique, complete genome) position: , mismatch: 7, identity: 0.781

--gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
acgaacc--gcacgaccggcacccggccgaggtt	Protospacer
  *** *  *****.** **************. 

79. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.75

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
ctcgcgggcaccgtccgcacggtcgatgcggg	Protospacer
  ********* ******* ****** . ** 

80. spacer 9.2|2513654|32|CP032698|PILER-CR matches to JN698995 (Mycobacterium phage Dori, complete genome) position: , mismatch: 8, identity: 0.75

gaagcgaccacgatccgcaggttcgggagggt	CRISPR spacer
gacacgaccacgatccgcaggtccgggttacc	Protospacer
** .******************.****  . .

81. spacer 9.2|2513654|32|CP032698|PILER-CR matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

gaagcgaccacgatccgcaggttcgggagggt	CRISPR spacer
tcggccaccacgatccgctggttcggcatgat	Protospacer
  .** ************ ******* * *.*

82. spacer 12.1|2818688|32|CP032698|CRISPRCasFinder matches to NZ_CP015204 (Rhodococcus sp. 008 plasmid pR8C1, complete sequence) position: , mismatch: 8, identity: 0.75

gaagcgagcacggtccgcagaccgaagggcct	CRISPR spacer
agcctgcgcacggtccgcagaccgcacggcct	Protospacer
..  .* ***************** * *****

83. spacer 16.1|3086539|32|CP032698|CRT matches to MH834612 (Arthrobacter phage Faja, complete genome) position: , mismatch: 8, identity: 0.75

cccgacagcccgcacccgaccaaccgacaggc	CRISPR spacer
ccggactgcccgcacccgaccaaatcctagga	Protospacer
** *** **************** .  .*** 

84. spacer 16.3|3086675|32|CP032698|CRT matches to NZ_LR134467 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 25, complete sequence) position: , mismatch: 8, identity: 0.75

accgacggcccgcacccgaacaaccggcacgc	CRISPR spacer
gccgacggcctgcacccgaccaacctgggccg	Protospacer
.*********.******** ***** * .*  

85. spacer 35.1|4020249|30|CP032698|PILER-CR matches to NZ_CP051471 (Rhodobacter sphaeroides strain CH10 plasmid pRspCH10B, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
ggccgcggcccgcagcccgaaacggggccc	Protospacer
. *************** .******* ...

86. spacer 35.1|4020249|30|CP032698|PILER-CR matches to NZ_CP030274 (Rhodobacter sphaeroides 2.4.1 plasmid pB, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
ggccgcggcccgcagcccgaaacggggccc	Protospacer
. *************** .******* ...

87. spacer 35.1|4020249|30|CP032698|PILER-CR matches to NZ_CP023551 (Rhodobacter sp. CZR27 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
ggccgcggcccgcagccggaaaccgggccg	Protospacer
. ****************.**** ** .. 

88. spacer 35.1|4020249|30|CP032698|PILER-CR matches to NZ_CP015215 (Rhodobacter sphaeroides strain MBTLJ-13 plasmid d, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
ggccgcggcccgcagcccgaaacggggccc	Protospacer
. *************** .******* ...

89. spacer 35.1|4020249|30|CP032698|PILER-CR matches to CP047034 (Rhodobacter sphaeroides strain DSM 158 plasmid pB, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
ggccgcggcccgcagcccgaaacggggccc	Protospacer
. *************** .******* ...

90. spacer 35.1|4020249|30|CP032698|PILER-CR matches to NZ_CP015291 (Rhodobacter sphaeroides strain MBTLJ-20 plasmid c, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
ggccgcggcccgcagcccgaaacggggccc	Protospacer
. *************** .******* ...

91. spacer 35.1|4020249|30|CP032698|PILER-CR matches to NZ_CP047040 (Rhodobacter sphaeroides strain 2.4.1 substr. H2 plasmid pB, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
ggccgcggcccgcagcccgaaacggggccc	Protospacer
. *************** .******* ...

92. spacer 35.1|4020249|30|CP032698|PILER-CR matches to NC_011962 (Rhodobacter sphaeroides KD131 plasmid pRSKD131A, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
ggccgcggcccgcagcccgaaacggggccc	Protospacer
. *************** .******* ...

93. spacer 35.1|4020249|30|CP032698|PILER-CR matches to NZ_CP017191 (Xanthomonas campestris pv. vesicatoria str. 85-10 plasmid p_XCV_1, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
tcgtgcggcccgcagccgaaaaggagtaac	Protospacer
 * .****************** *.**  .

94. spacer 35.1|4020249|30|CP032698|PILER-CR matches to NZ_CP018463 (Xanthomonas euvesicatoria strain LMG930 plasmid pLMG930.2, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
tcgtgcggcccgcagccgaaaaggagtaac	Protospacer
 * .****************** *.**  .

95. spacer 35.1|4020249|30|CP032698|PILER-CR matches to NC_007507 (Xanthomonas campestris pv. vesicatoria str. 85-10 plasmid pXCV183, complete sequence) position: , mismatch: 8, identity: 0.733

acccgcggcccgcagccgaaaacgggtttt	CRISPR spacer
tcgtgcggcccgcagccgaaaaggagtaac	Protospacer
 * .****************** *.**  .

96. spacer 38.1|4133520|30|CP032698|PILER-CR matches to NZ_CP044976 (Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B2) plasmid pPBL-H3_B2-1, complete sequence) position: , mismatch: 8, identity: 0.733

gacgcgggcacggtccgcaggatcgagagg	CRISPR spacer
aacacgggcacggtcagcaggatcatggac	Protospacer
.**.*********** ********. *.. 

97. spacer 38.3|4133520|31|CP032698|CRISPRCasFinder matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 8, identity: 0.742

cgggcacggtccgcaggatcgagaggggtta	CRISPR spacer
cgggcacggtccgcatgatcgacggacaaca	Protospacer
*************** ****** .*. . .*

98. spacer 47.4|4480898|30|CP032698|CRT matches to NC_017805 (Deinococcus gobiensis I-0 plasmid P1, complete sequence) position: , mismatch: 8, identity: 0.733

aaaagtgggcccggttcgtggtggcggggg	CRISPR spacer
cgtacggggcccagttcgtggtggtggggt	Protospacer
 . *  ******.***********.**** 

99. spacer 53.1|4844099|31|CP032698|PILER-CR matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 8, identity: 0.742

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
gtccgtcgatcatgcggaccgtgcccgactt	Protospacer
 .*. ****** *************** .*.

100. spacer 53.1|4844099|31|CP032698|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.742

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
cggggtcggtccagcggaccgtgcccgcgac	Protospacer
*    ***.*** ***************  *

101. spacer 53.1|4844099|31|CP032698|PILER-CR matches to MF614628 (Sinorhizobium phage phi3LM21, complete genome) position: , mismatch: 8, identity: 0.742

ccctctcgatcctgcggaccgtgcccgcttc	CRISPR spacer
cgcaaccgatcatgcggaacgtgcccgctgg	Protospacer
* *  .***** ****** **********  

102. spacer 71.3|5489965|34|CP032698|CRT matches to NC_020548 (Azoarcus sp. KH32C plasmid pAZKH, complete sequence) position: , mismatch: 8, identity: 0.765

gaagcgaccacgacccgcaggttcgagtgggttt	CRISPR spacer
gaagcgagcacgacgcgcaggttcggtggcgcat	Protospacer
******* ****** **********.  * *. *

103. spacer 77.1|5941588|31|CP032698|PILER-CR matches to NC_021347 (Rhodococcus phage E3, complete genome) position: , mismatch: 8, identity: 0.742

ccctctcgaccctgcgagccgtggccgcttc	CRISPR spacer
agatcgcgaccctgcgcgccgtggccatgtc	Protospacer
   ** ********** *********.. **

104. spacer 77.2|5941644|31|CP032698|PILER-CR matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 8, identity: 0.742

cccccggtcatgtgcgggccgtggtcgtttt	CRISPR spacer
gcggcggtcatgtgcaggccgtgggcgagct	Protospacer
 *  ***********.******** **  .*

105. spacer 77.2|5941644|31|CP032698|PILER-CR matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.742

cccccggtcatgtgcgggccgtggtcgtttt	CRISPR spacer
gcggcggtcatgtgcaggccgtgggcgagct	Protospacer
 *  ***********.******** **  .*

106. spacer 85.2|6253198|31|CP032698|CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.742

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
agccgtcgacccggccgaccgtgcccgcgaa	Protospacer
  *. ******* ** *************  

107. spacer 90.1|6763447|31|CP032698|CRISPRCasFinder matches to CP054927 (Streptomyces fulvissimus strain NA06532 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

aaccctctcgcccctgcggaccgtccccgct	CRISPR spacer
gcggccctcgcccctgcggaccgcccccgaa	Protospacer
.   *.*****************.*****  

108. spacer 90.1|6763447|31|CP032698|CRISPRCasFinder matches to NC_014918 (Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence) position: , mismatch: 8, identity: 0.742

aaccctctcgcccctgcggaccgtccccgct	CRISPR spacer
gaccgtctcgcccttgcggaccgtctggcca	Protospacer
.*** ********.***********.   * 

109. spacer 90.1|6763447|31|CP032698|CRISPRCasFinder matches to NZ_LR134456 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence) position: , mismatch: 8, identity: 0.742

aaccctctcgcccctgcggaccgtccccgct	CRISPR spacer
cacgtcgtcgcccgtgcggaccatccccgcc	Protospacer
 ** .. ****** ********.*******.

110. spacer 91.1|6963306|34|CP032698|CRISPRCasFinder matches to NZ_CP010990 (Pseudonocardia sp. EC080625-04 plasmid pFRP1-1, complete sequence) position: , mismatch: 8, identity: 0.765

cccgtctc---gatcctgcgggccgtggtcgcttctc	CRISPR spacer
---gtgtcgaggatcccgcgggccgtggtcgcgtccg	Protospacer
   ** **   *****.*************** **. 

111. spacer 91.1|6963306|34|CP032698|CRISPRCasFinder matches to NZ_CP012186 (Pseudonocardia sp. EC080619-01 plasmid pBCI1-1, complete sequence) position: , mismatch: 8, identity: 0.765

cccgtctc---gatcctgcgggccgtggtcgcttctc	CRISPR spacer
---gtgtcgaggatcccgcgggccgtggtcgcgtccg	Protospacer
   ** **   *****.*************** **. 

112. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NZ_CP012183 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-2, complete sequence) position: , mismatch: 8, identity: 0.75

gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
cgggcgggcacggccccgacccggccgacacc	Protospacer
 ..*************  ********** .* 

113. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NZ_LN606601 (Acetobacter senegalensis strain 108B plasmid 1P, complete sequence) position: , mismatch: 8, identity: 0.75

gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
ccatcgggcacggcccgcgcctggccgggccc	Protospacer
  * **************.**.*****.* * 

114. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.742

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
ccatcgagcacgggctgcgggcggccggggt	Protospacer
  * .*.********.**.*********** 

115. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NC_024971 (Streptomyces rochei plasmid pSLA2-S DNA, complete sequence, strain: 7434AN4) position: , mismatch: 8, identity: 0.742

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
gcgcagtacacgggccgcaggcggcccgtga	Protospacer
* .  * .****************** * **

116. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NC_024971 (Streptomyces rochei plasmid pSLA2-S DNA, complete sequence, strain: 7434AN4) position: , mismatch: 8, identity: 0.742

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
gcgccgtacacgggccgcaggcggcccgtga	Protospacer
* . .* .****************** * **

117. spacer 95.8|7390431|34|CP032698|CRT matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.765

gaagtgggcacgggccgcaggcggccggggattc	CRISPR spacer
ggagggggcacgggccgcatgcggcccgtgcccc	Protospacer
*.** ************** ****** * * ..*

118. spacer 95.8|7390431|34|CP032698|CRT matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.765

gaagtgggcacgggccgcaggcggccggggattc	CRISPR spacer
ggagggggcacgggccgcatgcggcccgtgcccc	Protospacer
*.** ************** ****** * * ..*

119. spacer 95.8|7390431|34|CP032698|CRT matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 8, identity: 0.765

gaagtgggcacgggccgcaggcggccggggattc	CRISPR spacer
ggagggggcacgggccgcatgcggcccgtgcccc	Protospacer
*.** ************** ****** * * ..*

120. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.719

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
ttcgcgggcacggtcggccgggtcgacggctc	Protospacer
  ************* ** ******* .*  .

121. spacer 2.5|1292536|32|CP032698|CRISPRCasFinder matches to NZ_CP053565 (Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gacgcgggcacggtccgcagggtcgagagggt	CRISPR spacer
tggacgggcacggtcagcggggtcgagtcgat	Protospacer
 . .*********** **.********  *.*

122. spacer 10.2|2628756|33|CP032698|PILER-CR matches to AP014720 (Arthrobacter sp. Hiyo8 plasmid pHiyo8-1 DNA, complete genome, strain: Hiyo8) position: , mismatch: 9, identity: 0.727

aaggagcgaccacggccgcaggccgagagccga	CRISPR spacer
gtcgagcgtccacggccgcaggacgagatgggc	Protospacer
.  ***** ************* *****   * 

123. spacer 10.3|2628812|35|CP032698|PILER-CR matches to NZ_CP047174 (Rathayibacter sp. VKM Ac-2760 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

gaccagccacccgcggcccgcggacgaaggcgggg	CRISPR spacer
gggcgctcccccgcggcacgcggacgagggcggga	Protospacer
*. *. .* ******** *********.******.

124. spacer 16.1|3086539|32|CP032698|CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 9, identity: 0.719

cccgacagcccgcacccgaccaaccgacaggc	CRISPR spacer
cccgacggcctgcacccgaccaaggccggggt	Protospacer
******.***.************     .**.

125. spacer 16.1|3086539|32|CP032698|CRT matches to MH020235 (Mycobacterium phage Batiatus, complete genome) position: , mismatch: 9, identity: 0.719

cccgacagcccgcacccgaccaaccgacaggc	CRISPR spacer
accgtcagcccgcacccgaacaactgtgcgcg	Protospacer
 *** ************** ****.*   *  

126. spacer 16.1|3086539|32|CP032698|CRT matches to FJ174693 (Mycobacterium phage Ramsey, complete genome) position: , mismatch: 9, identity: 0.719

cccgacagcccgcacccgaccaaccgacaggc	CRISPR spacer
accgtcagcccgcacccgaacaactgtgcgcg	Protospacer
 *** ************** ****.*   *  

127. spacer 16.1|3086539|32|CP032698|CRT matches to MH825707 (Mycobacterium phage MilleniumForce, complete genome) position: , mismatch: 9, identity: 0.719

cccgacagcccgcacccgaccaaccgacaggc	CRISPR spacer
accgtcagcccgcacccgaacaactgtgcgcg	Protospacer
 *** ************** ****.*   *  

128. spacer 20.1|3444592|34|CP032698|CRISPRCasFinder matches to NC_029033 (Achromobacter phage phiAxp-1, complete genome) position: , mismatch: 9, identity: 0.735

gaaaacccgttttcgtctgcgggccgcaggtggc	CRISPR spacer
aagacttcgttgtcgtctgcgggccgcatgtcac	Protospacer
.*.* ..**** **************** ** .*

129. spacer 45.1|4439171|33|CP032698|CRISPRCasFinder matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 9, identity: 0.727

aaaccccctcgatcctgcggaccgtgcccgctt	CRISPR spacer
gttgtccgtcgatcatgcggaccgtgcccgact	Protospacer
.   .** ****** *************** .*

130. spacer 57.1|4918292|33|CP032698|CRISPRCasFinder matches to NZ_CP046723 (Pantoea agglomerans strain ASB05 plasmid pASB05p1, complete sequence) position: , mismatch: 9, identity: 0.727

ccaaccccctgtcgtctgcggcccgcggtcgct	CRISPR spacer
ttacctgtatgtcgtctgcagcccgcggtggct	Protospacer
..* *. . **********.********* ***

131. spacer 57.1|4918292|33|CP032698|CRISPRCasFinder matches to NZ_CP034470 (Pantoea agglomerans strain CFSAN047153 plasmid pCFSAN047153_1, complete sequence) position: , mismatch: 9, identity: 0.727

ccaaccccctgtcgtctgcggcccgcggtcgct	CRISPR spacer
atacctgtatgtcgtctgcagcccgcggtggct	Protospacer
 .* *. . **********.********* ***

132. spacer 57.1|4918292|33|CP032698|CRISPRCasFinder matches to NZ_CP034149 (Pantoea agglomerans strain L15 plasmid pPagL15_1, complete sequence) position: , mismatch: 9, identity: 0.727

ccaaccccctgtcgtctgcggcccgcggtcgct	CRISPR spacer
atacctgtatgtcgtctgcagcccgcggtggct	Protospacer
 .* *. . **********.********* ***

133. spacer 57.1|4918292|33|CP032698|CRISPRCasFinder matches to NZ_CP034475 (Pantoea agglomerans strain CFSAN047154 plasmid pCFSAN047154_1, complete sequence) position: , mismatch: 9, identity: 0.727

ccaaccccctgtcgtctgcggcccgcggtcgct	CRISPR spacer
atacctgtatgtcgtctgcagcccgcggtggct	Protospacer
 .* *. . **********.********* ***

134. spacer 58.2|5049229|32|CP032698|PILER-CR,CRT matches to NC_008269 (Rhodococcus jostii RHA1 plasmid pRHL1, complete sequence) position: , mismatch: 9, identity: 0.719

cctgacccgtccgggtccgcaccggtcctgcc	CRISPR spacer
cagcttctttccggctcctcaccggtcctgcc	Protospacer
*    .*. ***** *** *************

135. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to NZ_CP018784 (Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence) position: , mismatch: 9, identity: 0.719

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
agctccgggacggtcggcacatgaccgggcgg	Protospacer
..  * ** ****** ************* * 

136. spacer 62.1|5195978|33|CP032698|CRT matches to NZ_CP029340 (Streptomyces sp. SM17 plasmid pSM17B, complete sequence) position: , mismatch: 9, identity: 0.727

ccctgccccgtccggccccgcgccggttctgcc	CRISPR spacer
ccctgccccgtcgggccccgcccctcgagcccc	Protospacer
************ ******** **     . **

137. spacer 62.1|5195978|33|CP032698|CRT matches to NZ_CP029340 (Streptomyces sp. SM17 plasmid pSM17B, complete sequence) position: , mismatch: 9, identity: 0.727

ccctgccccgtccggccccgcgccggttctgcc	CRISPR spacer
ccctgccccgtcgggccccgcccctcgagcccc	Protospacer
************ ******** **     . **

138. spacer 63.1|5243534|33|CP032698|CRISPRCasFinder matches to NZ_CP015882 (Ensifer adhaerens strain Casida A plasmid pCasidaAB, complete sequence) position: , mismatch: 9, identity: 0.727

ccagccacgcacggtcagcagacgcagagggta	CRISPR spacer
ccagccacgcaccgtcagcacacggtcgctgtt	Protospacer
************ ******* ***   .  ** 

139. spacer 63.1|5243534|33|CP032698|CRISPRCasFinder matches to NZ_CP030264 (Ensifer adhaerens strain Corn53 plasmid AB, complete sequence) position: , mismatch: 9, identity: 0.727

ccagccacgcacggtcagcagacgcagagggta	CRISPR spacer
ccagccacgcaccgtcagcacacggtcgctgtt	Protospacer
************ ******* ***   .  ** 

140. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to AP014693 (Ralstonia phage RSL2 DNA, complete sequence) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
gcgcttgtcgatcctgcggtccgtggtcgag	Protospacer
.  *.. ************ *********  

141. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to KT281796 (Mycobacterium phage Zakhe101, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

142. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to AY129335 (Mycobacterium virus Corndog, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

143. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MN428058 (Mycobacterium phage Krili, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

144. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MH020246 (Mycobacterium phage SchoolBus, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

145. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MT818418 (Mycobacterium phage Shida, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

146. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to NC_004685 (Mycobacterium phage Corndog, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

147. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to JN698993 (Mycobacterium phage Firecracker, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

148. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MH926062 (Mycobacterium phage Vorrps, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

149. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MG099943 (Mycobacterium phage Familton, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

150. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MG872838 (Mycobacterium phage JangDynasty, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

151. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MH590592 (Mycobacterium phage Ryadel, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

152. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MN585964 (Mycobacterium phage Blessica, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

153. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to KJ829260 (Mycobacterium phage YungJamal, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

154. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to NC_022057 (Mycobacterium phage Catdawg, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

155. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MT818425 (Mycobacterium phage NiebruSaylor, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

156. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to NC_022325 (Mycobacterium phage Dylan, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

157. spacer 65.1|5406027|31|CP032698|CRISPRCasFinder matches to MN428052 (Mycobacterium phage Smooch, complete genome) position: , mismatch: 9, identity: 0.71

aaccccctcgatcctgcgggccgtggtcgct	CRISPR spacer
cctgacctcgatactgcgggccggggtcctt	Protospacer
  .  ******* ********** **** .*

158. spacer 70.2|5488625|32|CP032698|PILER-CR matches to MT498057 (Microbacterium phage Cicada, complete genome) position: , mismatch: 9, identity: 0.719

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
gacggtgaccaaggcccgccgggtcgagatcg	Protospacer
.. .*.***** ******* *********  *

159. spacer 70.2|5488625|32|CP032698|PILER-CR matches to MK016497 (Microbacterium phage Johann, complete genome) position: , mismatch: 9, identity: 0.719

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
gacggtgaccaaggcccgccgggtcgagatcg	Protospacer
.. .*.***** ******* *********  *

160. spacer 70.2|5488625|32|CP032698|PILER-CR matches to MK016495 (Microbacterium phage Goodman, complete genome) position: , mismatch: 9, identity: 0.719

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
gacggtgaccaaggcccgccgggtcgagatcg	Protospacer
.. .*.***** ******* *********  *

161. spacer 71.1|5489850|34|CP032698|CRT matches to NZ_CP054620 (Azospirillum oryzae strain KACC 14407 plasmid unnamed5, complete sequence) position: , mismatch: 9, identity: 0.735

gaagcgaccacggcccgcagggtcgggagggttt---	CRISPR spacer
tcggcgaccacggccggcacggtcgggcg---ttggg	Protospacer
  .************ *** ******* *   **   

162. spacer 77.2|5941644|31|CP032698|PILER-CR matches to NZ_CP032685 (Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence) position: , mismatch: 9, identity: 0.71

cccccggtcatgtgcgggccgtggtcgtttt	CRISPR spacer
ctgccggtcatgtacgggacgtggtccgaag	Protospacer
*. **********.**** *******     

163. spacer 77.2|5941644|31|CP032698|PILER-CR matches to NZ_CP032690 (Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence) position: , mismatch: 9, identity: 0.71

cccccggtcatgtgcgggccgtggtcgtttt	CRISPR spacer
ctgccggtcatgtacgggacgtggtccgaag	Protospacer
*. **********.**** *******     

164. spacer 77.3|5941700|32|CP032698|PILER-CR matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 9, identity: 0.719

gcccgtgttcgtccgcgggctgtggtcgcgtc	CRISPR spacer
ccccgcgttcgtccgcgcgctgtgccggagca	Protospacer
 ****.*********** ****** . * *. 

165. spacer 81.1|6018757|32|CP032698|PILER-CR matches to NC_015184 (Agrobacterium sp. H13-3 plasmid pAspH13-3a, complete sequence) position: , mismatch: 9, identity: 0.719

atgaaacccgccttcgtgtgcggaccgtgccc	CRISPR spacer
caggtctgcggcttcctgtgcggaccgtgccc	Protospacer
  *.  . ** **** ****************

166. spacer 85.2|6253198|31|CP032698|CRT matches to NZ_CP053565 (Pseudonocardia sp. Gen01 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

ccctctcgaccctgcggaccgtgcccgcgtc	CRISPR spacer
tcgactcgaccccgctgaccgtgcccgtcca	Protospacer
.*  ********.** ***********. . 

167. spacer 85.4|6253315|31|CP032698|CRT matches to NZ_CP015204 (Rhodococcus sp. 008 plasmid pR8C1, complete sequence) position: , mismatch: 9, identity: 0.71

agcccttcggtctgcggaccgtgctcgcttc	CRISPR spacer
ggccgtgcggtctgcggaccgtgcgcaggct	Protospacer
.*** * ***************** *.  ..

168. spacer 90.1|6763447|31|CP032698|CRISPRCasFinder matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 9, identity: 0.71

aaccctctcgcccctgcggaccgtccccgct	CRISPR spacer
gggcgcctcgcccctgcggaccttccgcgac	Protospacer
.. * .**************** *** ** .

169. spacer 95.1|7390256|34|CP032698|PILER-CR matches to NC_002679 (Mesorhizobium japonicum MAFF 303099 plasmid pMLa, complete sequence) position: , mismatch: 9, identity: 0.735

ccagccccgcacggtccgcggacgaatgcgggtt	CRISPR spacer
gccttccggcacggtcggcggacgaatgccgcgt	Protospacer
 *  .** ******** ************ *  *

170. spacer 95.1|7390256|34|CP032698|PILER-CR matches to NZ_CP012477 (Arthrobacter sp. ERGS1:01 isolate water plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

ccagccccgcacggtccgcggacgaatgcgggtt	CRISPR spacer
tgatccccgcccggtccgcggaagaatggcggga	Protospacer
. * ****** *********** *****  **  

171. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 9, identity: 0.719

gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
cactggggcacggcccgctccccgccgacggc	Protospacer
 *   ************* *** ***** *  

172. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 9, identity: 0.719

gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
cactggggcacggcccgctccccgccgacggc	Protospacer
 *   ************* *** ***** *  

173. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
cgggcgggcacggcccgcaacccgccacgcaa	Protospacer
 ..**************** ** ***. *  *

174. spacer 95.3|7390372|34|CP032698|PILER-CR matches to NZ_LN907828 (Erwinia gerundensis isolate E_g_EM595 plasmid pEM01, complete sequence) position: , mismatch: 9, identity: 0.735

--ccagccacgcacggctggcagccgaaaacgggtt	CRISPR spacer
gctcggt--cgcccggctggcagcggaaaacggcat	Protospacer
  .*.*.  *** *********** ********  *

175. spacer 95.3|7390372|34|CP032698|PILER-CR matches to NZ_CP010421 (Azotobacter chroococcum NCIMB 8003 plasmid pAcX50f, complete sequence) position: , mismatch: 9, identity: 0.735

ccagccacgcacggctggcagccgaaaacgggtt---	CRISPR spacer
ccagccaggcacggctggccgccg---gccagtccag	Protospacer
******* *********** ****   .* .**.   

176. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NC_015952 (Streptomyces violaceusniger Tu 4113 plasmid pSTRVI02, complete sequence) position: , mismatch: 9, identity: 0.71

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
cggccgggtacgggccgcaggcggccgtgct	Protospacer
 .. .***.****************** *  

177. spacer 95.4|7390431|31|CP032698|PILER-CR matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 9, identity: 0.71

gaagtgggcacgggccgcaggcggccgggga	CRISPR spacer
tcgatgcgcacgggccgcaggcggtcgcgac	Protospacer
  ..** *****************.** *. 

178. spacer 95.6|7390315|35|CP032698|CRT matches to NC_008712 (Paenarthrobacter aurescens TC1 plasmid pTC1, complete sequence) position: , mismatch: 9, identity: 0.743

gaagcgggcacggcccgcacccggccgaggcattt	CRISPR spacer
ggcccgggcagggcccgcacccggccgtggtggtc	Protospacer
*.  ****** **************** **.. *.

179. spacer 10.2|2628756|33|CP032698|PILER-CR matches to NC_012586 (Sinorhizobium fredii NGR234 plasmid pNGR234b, complete sequence) position: , mismatch: 10, identity: 0.697

aaggagcgaccacggccgcaggccgagagccga	CRISPR spacer
ggtgagcgaccccggcggcaggccgagggtacg	Protospacer
.. ******** **** **********.*.  .

180. spacer 16.3|3086675|32|CP032698|CRT matches to NZ_CP025015 (Rhizobium leguminosarum strain Norway plasmid pRLN3, complete sequence) position: , mismatch: 10, identity: 0.688

accgacggcccgcacccgaacaaccggcacgc	CRISPR spacer
aaacgcggcccgcgcacgaacaaccggctgtt	Protospacer
*   .********.* ************   .

181. spacer 16.3|3086675|32|CP032698|CRT matches to NZ_CP025015 (Rhizobium leguminosarum strain Norway plasmid pRLN3, complete sequence) position: , mismatch: 10, identity: 0.688

accgacggcccgcacccgaacaaccggcacgc	CRISPR spacer
aaacgcggcccgcgcacgaacaaccggctgtt	Protospacer
*   .********.* ************   .

182. spacer 16.3|3086675|32|CP032698|CRT matches to NZ_CP049734 (Rhizobium leguminosarum strain A1 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

accgacggcccgcacccgaacaaccggcacgc	CRISPR spacer
aaacgcggcccgcgcacgaacaaccggctgtt	Protospacer
*   .********.* ************   .

183. spacer 16.3|3086675|32|CP032698|CRT matches to NZ_CP025505 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvC, complete sequence) position: , mismatch: 10, identity: 0.688

accgacggcccgcacccgaacaaccggcacgc	CRISPR spacer
aaacgcggcccgcgcacgaacaaccggctgtt	Protospacer
*   .********.* ************   .

184. spacer 16.3|3086675|32|CP032698|CRT matches to CP049734 (Rhizobium leguminosarum strain A1 plasmid pRLa11, complete sequence) position: , mismatch: 10, identity: 0.688

accgacggcccgcacccgaacaaccggcacgc	CRISPR spacer
aaacgcggcccgcgcacgaacaaccggctgtt	Protospacer
*   .********.* ************   .

185. spacer 16.3|3086675|32|CP032698|CRT matches to NZ_CP054024 (Rhizobium sp. JKLM12A2 plasmid pPR12A203, complete sequence) position: , mismatch: 10, identity: 0.688

accgacggcccgcacccgaacaaccggcacgc	CRISPR spacer
aaacgcggcccgcgcacgaacaaccggctgtt	Protospacer
*   .********.* ************   .

186. spacer 16.3|3086675|32|CP032698|CRT matches to NZ_CP022669 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR4, complete sequence) position: , mismatch: 10, identity: 0.688

accgacggcccgcacccgaacaaccggcacgc	CRISPR spacer
aaacgcggcccgcgcacgaacaaccggctgtt	Protospacer
*   .********.* ************   .

187. spacer 16.3|3086675|32|CP032698|CRT matches to NZ_CP054035 (Rhizobium sp. JKLM13E plasmid pPR13E04, complete sequence) position: , mismatch: 10, identity: 0.688

accgacggcccgcacccgaacaaccggcacgc	CRISPR spacer
aaacgcggcccgcgcacgaacaaccggctgtt	Protospacer
*   .********.* ************   .

188. spacer 16.3|3086675|32|CP032698|CRT matches to NZ_CP050090 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b4, complete sequence) position: , mismatch: 10, identity: 0.688

accgacggcccgcacccgaacaaccggcacgc	CRISPR spacer
aaacgcggcccgcgcacgaacaaccggctgtt	Protospacer
*   .********.* ************   .

189. spacer 21.1|3487093|34|CP032698|CRISPRCasFinder matches to NC_006674 (Gluconobacter oxydans 621H plasmid pGOX3, complete sequence) position: , mismatch: 10, identity: 0.706

gaaaacccgttctcatctgcggaccgtgcgtggc	CRISPR spacer
ccaaacccgttctcatccacggaccgcgtggaca	Protospacer
  ***************..*******.*.* .  

190. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to NZ_CP013419 (Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence) position: , mismatch: 10, identity: 0.697

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
agcgccccgcacggccggcagccgaaacaatgc	Protospacer
   *** ********* **********  . *.

191. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to NZ_CP013415 (Burkholderia ubonensis strain MSMB2035 plasmid pMSMB2035, complete sequence) position: , mismatch: 10, identity: 0.697

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
agcgccccgcacggccggcagccgaaacaacgc	Protospacer
   *** ********* **********  . *.

192. spacer 42.2|4174702|34|CP032698|CRT matches to CP042595 (Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence) position: , mismatch: 10, identity: 0.706

aacctgccccgtccggggccgcaccggttctgcc	CRISPR spacer
cacctgcaccctccggggccgcaccgacttccag	Protospacer
 ****** ** ***************..*..   

193. spacer 42.4|4174703|34|CP032698|PILER-CR matches to CP042595 (Streptomyces albogriseolus strain LBX-2 plasmid pSALBX2, complete sequence) position: , mismatch: 10, identity: 0.706

aacctgccccgtccggggccgcaccggttctgcc	CRISPR spacer
cacctgcaccctccggggccgcaccgacttccag	Protospacer
 ****** ** ***************..*..   

194. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to NZ_CP015743 (Shinella sp. HZN7 plasmid pShin-07, complete sequence) position: , mismatch: 10, identity: 0.688

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
gaagacgggcaaggtccgcaggttcaaggaat	Protospacer
..*..****** *************.**... 

195. spacer 59.3|5075332|32|CP032698|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 10, identity: 0.688

gaagcgggcacggtccgcacatgaccgggggt	CRISPR spacer
ccaccgggcattgtccgcacatgaccgatccg	Protospacer
  * ******. ***************.    

196. spacer 62.1|5195978|33|CP032698|CRT matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 10, identity: 0.697

ccctgccccgtccggccccgcgccggttctgcc	CRISPR spacer
gccggccccgtccgggcccgcgccgtcgtcaac	Protospacer
 ** *********** ********* . ... *

197. spacer 70.2|5488625|32|CP032698|PILER-CR matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

agaagcgaccacggcccgcagggtcgagaggg	CRISPR spacer
ggcggcgatctcggcccgcagggtcgaatatc	Protospacer
.* .****.* ****************. .  

198. spacer 71.1|5489850|34|CP032698|CRT matches to NZ_CP021029 (Rhizobium sp. TAL182 plasmid pRetTAL182e, complete sequence) position: , mismatch: 10, identity: 0.706

gaagcgaccacggcccgcagggtcgggagggttt	CRISPR spacer
ctatccaccacggccagctgggtcgggaggcgag	Protospacer
  * * ********* ** ***********    

199. spacer 91.1|6963306|34|CP032698|CRISPRCasFinder matches to MT740745 (Ralstonia phage Raharianne, complete genome) position: , mismatch: 10, identity: 0.706

cccgtctcgatcctgcgggccgtggtcgcttctc	CRISPR spacer
gtcggctcgatcctgcgcgccgtggtggaggcca	Protospacer
 .** ************ ******** *   *. 

200. spacer 91.1|6963306|34|CP032698|CRISPRCasFinder matches to MT740726 (Ralstonia phage Albius, complete genome) position: , mismatch: 10, identity: 0.706

cccgtctcgatcctgcgggccgtggtcgcttctc	CRISPR spacer
gtcggctcgatcctgcgcgccgtggtggaggcca	Protospacer
 .** ************ ******** *   *. 

201. spacer 91.1|6963306|34|CP032698|CRISPRCasFinder matches to MT740743 (Ralstonia phage Hyacinthe, complete genome) position: , mismatch: 10, identity: 0.706

cccgtctcgatcctgcgggccgtggtcgcttctc	CRISPR spacer
gtcggctcgatcctgcgcgccgtggtggaggcca	Protospacer
 .** ************ ******** *   *. 

202. spacer 95.1|7390256|34|CP032698|PILER-CR matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 10, identity: 0.706

ccagccccgcacggtccgcggacgaatgcgggtt	CRISPR spacer
gggcgcccgcacgggccgaggacgaatgcggccc	Protospacer
  .  ********* *** ************ ..

203. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NZ_CP010727 (Phaeobacter inhibens strain P88 plasmid pP88_b, complete sequence) position: , mismatch: 10, identity: 0.688

gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
ctgctggtcacggcccgcacccggacgaccta	Protospacer
  . .** **************** ***  .*

204. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NC_009955 (Dinoroseobacter shibae DFL 12 = DSM 16493 plasmid pDSHI01, complete sequence) position: , mismatch: 10, identity: 0.688

gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
ctgctggtcacggcccgcacccggacgaccta	Protospacer
  . .** **************** ***  .*

205. spacer 95.2|7390315|32|CP032698|PILER-CR matches to NZ_CP021115 (Rhodobacteraceae bacterium strain G7 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

gaagcgggcacggcccgcacccggccgaggca	CRISPR spacer
ctgctggtcacggcccgcacccggacgactta	Protospacer
  . .** **************** ***  .*

206. spacer 95.6|7390315|35|CP032698|CRT matches to NC_009469 (Acidiphilium cryptum JF-5 plasmid pACRY03, complete sequence) position: , mismatch: 10, identity: 0.714

gaagcgggcacggcccgcacccggccgaggcattt	CRISPR spacer
aagacgggcacggcccgctcccgcccgaggatgac	Protospacer
.*..************** **** ******    .

207. spacer 34.4|4013847|36|CP032698|CRT matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 11, identity: 0.694

aaaaccctcggtcacgtgcggaccgtgctcgcttct	CRISPR spacer
cggttcctcgggcacgtgcggagcgtgctcgaggcg	Protospacer
 .. .****** ********** ********   * 

208. spacer 55.2|4866532|34|CP032698|PILER-CR matches to NZ_CP023451 (Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p2, complete sequence) position: , mismatch: 11, identity: 0.676

acctgccccgtccgggccagcgccggttctgctg	CRISPR spacer
ccctgccctgcccgggccagcgccgaggcgagca	Protospacer
 *******.*.**************.  * . ..

209. spacer 55.2|4866532|34|CP032698|PILER-CR matches to NZ_AP018666 (Sphingobium amiense strain DSM 16289 plasmid pSAMIE_3, complete sequence) position: , mismatch: 11, identity: 0.676

acctgccccgtccgggccagcgccggttctgctg	CRISPR spacer
ccctgccctgcccgggccagcgccgaggcgagca	Protospacer
 *******.*.**************.  * . ..

210. spacer 55.2|4866532|34|CP032698|PILER-CR matches to CP021185 (Sphingomonas wittichii DC-6 plasmid pDC04, complete sequence) position: , mismatch: 11, identity: 0.676

acctgccccgtccgggccagcgccggttctgctg	CRISPR spacer
ccctgccctgcccgggccagcgccgaggcgagca	Protospacer
 *******.*.**************.  * . ..

211. spacer 55.2|4866532|34|CP032698|PILER-CR matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 11, identity: 0.676

acctgccccgtccgggccagcgccggttctgctg	CRISPR spacer
gccggccccgtccgggcccgcgccgtcgtcaacg	Protospacer
.** ************** ****** . ... .*

212. spacer 59.1|5075217|32|CP032698|CRISPRCasFinder matches to MN694483 (Marine virus AFVG_250M1031, complete genome) position: , mismatch: 11, identity: 0.656

gaagcgaccacgacccgcaggatcgagagggt	CRISPR spacer
atctttaccacgaccagcaggatcaagagcca	Protospacer
.   . ********* ********.****   

213. spacer 71.3|5489965|34|CP032698|CRT matches to NZ_CP024427 (Paracoccus yeei strain TT13 plasmid pTT13-5, complete sequence) position: , mismatch: 11, identity: 0.676

gaagcgaccacgacccgcaggttcgagtgggttt	CRISPR spacer
tccgcgaccacgcccagcaggttcgaggtcatca	Protospacer
   ********* ** ***********   .*. 

214. spacer 71.3|5489965|34|CP032698|CRT matches to NZ_CP020443 (Paracoccus yeei strain FDAARGOS_252 plasmid unnamed3, complete sequence) position: , mismatch: 11, identity: 0.676

gaagcgaccacgacccgcaggttcgagtgggttt	CRISPR spacer
tccgcgaccacgcccagcaggttcgaggtcatca	Protospacer
   ********* ** ***********   .*. 

215. spacer 95.3|7390372|34|CP032698|PILER-CR matches to NZ_CP013419 (Burkholderia sp. MSMB0266 plasmid pMSMB0266, complete sequence) position: , mismatch: 11, identity: 0.676

ccagccacgcacggctggcagccgaaaacgggtt	CRISPR spacer
agcgccccgcacggccggcagccgaaacaatgca	Protospacer
   *** ********.***********  . *. 

216. spacer 95.3|7390372|34|CP032698|PILER-CR matches to NZ_CP013415 (Burkholderia ubonensis strain MSMB2035 plasmid pMSMB2035, complete sequence) position: , mismatch: 11, identity: 0.676

ccagccacgcacggctggcagccgaaaacgggtt	CRISPR spacer
agcgccccgcacggccggcagccgaaacaacgca	Protospacer
   *** ********.***********  . *. 

217. spacer 95.6|7390315|35|CP032698|CRT matches to NZ_CP012183 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-2, complete sequence) position: , mismatch: 11, identity: 0.686

gaagcgggcacggcccgcacccggccgaggcattt	CRISPR spacer
cgggcgggcacggccccgacccggccgacaccgcc	Protospacer
 ..*************  ********** .*  ..

218. spacer 95.8|7390431|34|CP032698|CRT matches to NC_024970 (Streptomyces aureofaciens strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 11, identity: 0.676

gaagtgggcacgggccgcaggcggccggggattc----	CRISPR spacer
----ggggcacgggccgcatgcggcccgtgccccctcc	Protospacer
     ************** ****** * * ..*    

219. spacer 95.8|7390431|34|CP032698|CRT matches to NZ_KJ396772 (Streptomyces lavendulae subsp. lavendulae strain CCM3239 plasmid pSA3239, complete sequence) position: , mismatch: 11, identity: 0.676

gaagtgggcacgggccgcaggcggccggggattc----	CRISPR spacer
----ggggcacgggccgcatgcggcccgtgccccctcc	Protospacer
     ************** ****** * * ..*    

220. spacer 95.8|7390431|34|CP032698|CRT matches to NZ_CP024986 (Streptomyces lavendulae subsp. lavendulae strain CCM 3239 plasmid pSA3239, complete sequence) position: , mismatch: 11, identity: 0.676

gaagtgggcacgggccgcaggcggccggggattc----	CRISPR spacer
----ggggcacgggccgcatgcggcccgtgccccctcc	Protospacer
     ************** ****** * * ..*    

221. spacer 95.5|7390256|37|CP032698|CRT matches to NC_023284 (Streptomyces sp. F2 plasmid pFRL4, complete sequence) position: , mismatch: 13, identity: 0.649

ccagccccgcacggtccgcggacgaatgcgggtttcc	CRISPR spacer
gggcgcccgcacgggccgaggacgaatgcggcccgaa	Protospacer
  .  ********* *** ************ ..   

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	2341048 : 2352412	16	Mycobacterium_phage(55.56%)	NA	NA
DBSCAN-SWA_2	5286774 : 5353693	54	Staphylococcus_phage(33.33%)	holin,protease	NA
DBSCAN-SWA_3	6662201 : 6668338	7	Streptomyces_phage(33.33%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>CP032698|2341048:2352412|DBSCAN-SWA
CTCATGCTGCCTCCTTGTGAATTATGTTGCAGAGATCGCAGACCTGGCCATCGGCCGTATATCCGCAGCCCCAGCTCTTTCCGTAGACCGAAACATCCGTGTCGATGAGTACGCCCTGCATGACTTCCTTCATGATCTGAGCGGCCTTTGTCGTGGCATTGAGGGCGTGCTCCTCCGGGAACTGGAAGATCACCTCGTCATGCACGGGCAGAAGCATGAATTGCCCGTATCCGGCTTCCAGGAGTCGCAGAATGGCCCGGCCAGTCACATCCCGGCTTGCGCTTTGCACGGCATAGTTGAGGGCCGCGTATGGGCGCCGCTTGTCCACGTAGAGGCGTCGGCCCGTGTTCGTGGTGATGTAGCCCTTCCGGCGCGCTTCTCGCTGAAGGTCCTCGGAGTACTGCTCCACGCCGGGGAAGACCTTGAAGAACCCCTTGATGGCTCGCTCAGCGACTTCCCGAGTGACGCCGGCCTGGCTCATCAGGGCGGCCGGCCCGCCTCCGTACACCGTCAGGAAGTTGGTCATCTTCCCTGTTTTGCGGTCTACTTCGGCGGCGTCCGCGGTGATCTGGTGAAGGTCGGCTTCCTCGCGGAACGCCTTTTTCATTGCCTTGTCTCCCGACAGGGCGGCCAGGACCCGGAGTTCCTGGGCCTTGTAGTCCACGGCGCAGATGACCATGCCCGGATCGGCTATAAATCCGCGCCGGACCAACGAGTCTCCGGAGGGGAAGGTCTGCGCGGGTATAGCTCCGGAGATCGACATCCGAGCCGTCCTGGCGCCCATCGAGCGGATATCGGCGTGCAGCCGGTGTGCCCCGTCTCGGTTGGCTAGGGCGTTGTCGAACCAAGTGGCCTTGGCTTTGGCAGCCTTCTTGCCCCGGTAGATGGCTTCGCACAGCGGGTCATCTATGTGGGCCTTCAGTAGATGGTCGTCCACCTTGGGCTGACCTGTCGGAGTCGTCTCGGTGGGGATGACGCCTCGGCTGATGACTGCCGCCCCAACCTGCCGGGGGCTGTTGATGTTCTCCAGTCCGAGCTTCGCCGCGATGTCCTTGTAGTGGTGCTCCGTGGAGGCCAGCTCGGCTGCCCGGTCCTCGATGTATGGCACGTCGGCCTTGATGCCGCGACGCACCATGTAGGCGCAGGCGGCTGCCAGCTCGTGTTCGTAGCGCACGAGCTTGCGGGCCGTGGTCGGAATCTGGGGCTTGAGGAGCTTCACCAGGCGGAAGGCGAGGATCGGGTCCATACCGGCGTAGAGGTTGAACCCCTCATGCTCCAGCGGGATCACCGGCCATATGTCCGCCTTCTTGATGCCCAGCTCCTTGGCGATGACGGTCATGCTCGCCTTCACCTCATCGGCCACCGTCGCGGAGACGTAGTGGCGGGTGAGTTCTTCGAGCGAGTGGCCTACGCCACCGTCTTTCCGACCTCGACTGTCTACGAGGTGGGCGGTGATGCGGGAGTCCACGAGGCGAGGGAAGACAGACTCGGCCGGCACCCCCCAGACTCGATCCATGCAGAGGATGTCGTAGGTGCCGTTCTGCATGGCCAGCTTCTCGATCCAGCCAACGGCCTTGATGGCGTCTTCCTGGAAGAGGCCACCCCTCTCGGTGGGGAGGACGTAGCTCTCGTGCGCGTTGCCGAACTGGGCAAGGCGTATACGGAAACCGTCCTCCCACCAAGAGAGCCCGTCAGTCTCGGTGTCGAAACCCAGGGCTCGGCGGTTGTTGATCACGAAGTGTCGGAATTCTGGGAGGTCTTCTTCAGTCTCAACTACGTTGATGCGGACTTCGGAGCCGTTAATGGCGTAGTTGATGACCTTCATTCGATTCCTCCGTATGTCACATCCCAACTTGATGGGCTCAAAAAGGGGGCTTATCTGCTTGCGACGCCTCACGCTCTGCGGTGAGGGCGTCATACCTGGCTTCCAGTTCCGTGTACTCCTGGACGGCTATGTCCAACTCGGCTTCGAGGCCGTCGATGTACGTGTTGAGCCGGTTGTTGACTTTCTGGAAGTGTGCATTGGTTCGGTTTGCCATCTCAACTTCCAGGCGAAGCAGTCGGATTTGGTTCGCCTTCTTCCCAAGCATCAGTAAGTCCCTTCCAGGATCGAGGGGAACTCAGGCTCGGAAGGTTCAGGTCCGATGCGTCGCTCGACGGTCATGTTGCAGTGGTCGTAGACCCAGAGGGGGATTTCGTCCCAGCTATCGAACACCGGCCGCCCCCAGAGCCGCAGTGACCTCGTTCAGCCGCTCCTCGGCGCCCAAGCCCTCTTCCCAAGCCATCTCGCGAGCGGCGTCAGCCTTGATGCGCTCCAAGTGGCCCTTCCGGTCAGCGAGGTGCTTCACCAGGCGCACGTACCGGTGACCGCTTCCAGTGCCCTCGGCATCGCGCTTGAGCTTGGCTACCTCTTCACCGAGCTGGCGCGCGGAGTTGCGTGCGTCTTCGTAACGCTTGAGCCAGTACCGCTTGGCGTCTTCGACCTCGCGGGCCTTGCGGGTCACCTCGGCAAGGTCCTTGCGAAGCGACTCGATGAGCGCCTTGTTCTCCTCCTTGACCTCGATCGTGACCTTGCTGAGCGGCACGTTCTTGAGATCGATCTCCGAGTTGCCGGCCTCGTAGGCATTCGAGGTCCACATGTAGGTCATTCGTTCACTCCGGGGGTTTCACAGGCCGGGCATGCGGCCTGGAGTTCAGGGGTTGCGTTGCGGGGGTACTGATCCACGAATGCGAAGCCACAGGCGCATTCGTAGTAGGCCAGCACGTCTACGAGCTCTGCCATCAGGGGGCAACTCGCCCGTGCTTCACGAACGCCTCGTGCGTGGTCGGCATGAGGCGCTTGAAGTGCTCCTCCATCTGGTCAGCAACCATCTGGATCTCGACCTGGGGGAATGACTTGTACTTCGCGTCGTCGCTCTTGGTGCGCAGCGAGAGGAAGTGCATCAGCGACCGCGGATTGCAGGTGACGTAGAAGGTGCTGAAGATGCCGACAGGCAGCACGGAACGGGCAACTTCACGGGCGACGCCTGCGGCCAGCATGTTCTGGTAGGACTCCCAGGCCGTGGCGTAGGCAGTGCGGGTGGACTCGGAGGCCACGAACCACTGCTCGAACGTGCCTGGCTTGAAGTCGTACTGGCCGGCCTTGCCCACCTGGACTAGGGGGCGTTCCCCGGCCGGTACGTAGAAGACGGGCTCCAGCTCGCGGTAGCGGCCGGACTCCTCGTTGTAGGACATTCCGGCGCGGTGCCTCATGAACTCGCGGACGACGAAGATTGGGGCGGAGATCCGGAACGTGAACGAACCGTGCTCGAAGGGGCTGCCGTGCCGATCACGGAGCAGGAAGCTGATGAGGCCTTGATCCTTCTCCTCGTCGCGGTCCAGGGCATTGCGGCCGATGGTGCTGACACGAGCGGCCATGCAGATCATCTCGTCAGTGGCGAGCTGCTGCACCAGCCCCACGTCCATGGTGCTTTTGAACCTCACGATGACCTTTCAGGAGTACCGGGGCCGGGCCGGCGACCCGGCCCCGGTGTCACATCTCAACTTTGAGAGCTGGCGAAATTGCTAGTTCTTCAGCTCGAACTTGCCGGACTTCTTGTTGAGGAAGGCGGGTGCGCACTTGTCGTCGCCCTTACGCTCGTCGGCGTTGCAGAAGTACGCCTCCCAGGTGCCCTTGGCGACATGGGTGCGACCGTGCTCGCAGTCGGTGACGCCCTGGTGACCGCCGTCGCCTCCGGAGTTCTGGACCTTGCCGCCGGAGAAGCTGTTCTTGCCTGCGGGCTTGGCGCCCTTGTCCTTGGCGTTCAGTTCGGTGCTGTACTTCTGGATCTTGGCCATGCGCTTCATGAGGGAGGCGAGCGCGCTGGCCTCCTCGTCGAGCATGGCGTCCATGTCGGCGACGGTGGCTGCACGGAGGACGAGGAGCGAGGCGTCATAGCCTTCGCCGCCCTTGAAGCTCAGCGTTACGCCTTCCTGCGTGTGGGTGGTGGGAGTGGTCATGGGCGACTCCTTGGGGGTCTCGGCAGTGGTGGTATCGGTGGTCGGCTCGCCCCAGGGGGAGCTTCCGAAGGGGTTCTCGCTCATGAATGAATCCTTTCAAATTTGAGTGTCACATCTCAACTTGTGGTGCTGTGAAGTGGATCTCAGATTGGACAGGCGCCAGAGGCACAGACCTCGTCATATCCCGTATCCCATACGGCCTCGCCCACAATGGCGACTTCATAGAGATAGCGCTCCTTCGAGATCCGCTCATAGGGCGTCTGGGGGCGGCTCATCTCCGGGAAAATAGTCGTCCCCTTGAGCGCCGGCATGTACCCGAGCATCACTCGGGCAACGTCATCCGGGCCGTACTTCTCCGGATCGACAGAGGCCGTGTACGAGACCGCCTGGTCGGCCCACAGCTCCTGGTAGAGCCGCTGCACGGTGAGCATCTGCACGAGGCTCAACTCCCCCGCGTGCTCGAACACATCGGCCAGCTCGGGGTGCGCGGCCAGAAGCGGGTCCATGGTCGGGATCTCGACCACGGACGTGGTGGCTCCGTAGACACAGGGCTCCACCTTGTACCCCTTCCCGCGGTACTCCTCCACCTGCGCCTTCTCCGAGGGCTCCAGGTCCGAGAAGCGAATCCGGCGCAGGAAGTAGGCCGCGAAGGGCGCGTGGATGCCCTCGCCGCTGACGGAGGCCAGCTTGCTCGTGGTACCGGTCGGGGCGATGACTCGCTTCTTGATCGGCACGGGGATACGCAGCTCGTTGGCGTATTCGGCTGCGGACTGGTCCACGGTCTGGGCCATGAACTTCAGATCCGAGCGAACCCGCGGATTGTAAGGAGCGCTGCTGTACTTGATGCCCTGCTTGAAGAGGAAGTCGGCAAAGCCCAGATGCCCTACGCCGATCCTGCGGTACTTGCTGATCGCCTCCTGCGACTTCGGGTCGGCCACCTTCGCGAAGGTGGCTCGGATCAGGTAGCGGGTGGCGTAGCGGTGAGCGTCGTAGAGGCCCTGGCTGTCCGACTCGCCATCCCGTACGAATGCCCCGAGGTTCACGGAGCCCAGGTTGCAGGGCTCCCAGGGGGTCAGCGTGGCTTCCCCGCACGGGTTGGTGGTGTAGGTACCGTCTACCTCCCCCACACTCGTCAGCGAGCGGTTCCAGAAACCAGGCTCCCCGTTCTTGAGCGCACCCTCGGCGAGGGCCTGCATGACCTTCACCGCGTGCTCCTGGCCGTCCTCGACGGCCGTGAGGAAGTGGTCGTCCACTTCCACGCTGATGTTGGTCGTCCACATGGCGAGCTGATCGCCCTTGACCTTCAGGAACTCCCAGATGAGCTGGTCATCCCAGGCCATGATGCTCATGCGTGCGGAGCGCCGAACTCCCCCTGCCACGACGGCCATTGCGATCTGATGGTCAATGGCCATGGCGTCCATGCCGTTCATCGGCCACCCTGCGGCGTCGGTGAGGATCTTGCCGACCTCGACCATCATCTTCGCGAACGGCAGCGGCCCCGATGCGGTTCCGCCGAAGTTGCGCAGTGGCGTCCCCTTGCCGCGGACCCTGCTCACGTCATAGACGCGGTTCTCGTGCCGGGTGTCTGGGCTGTGGGCTGTGTCGATCAGGTCGCCCAGGGCTCCCGCCCAGCCTTCGCGGGAATCCTCCACGCTGTAGGCCCCGGCCCACTCGTAGTCGTACTCGGTGCTGATGACGCCGGCCTCGACCAGATCGAGGTAGTCAGGGTGTGCCGGGTCGCAGACGATATGGACGTGGACCCGGTTCTCGATCGCGGAGAACCCACTGAAGTACCGGCTGCTGTAGTTGGCGCCGACGCCACCTCCTTCGGCCAGGCGAAGGAGAGTGAAGCGGAAATGTTCGGCCGGGTCCGCAGGCACCCAGCCGCTCGCCCAGCAGTTGTTCAGCGCAAAGTCGTTGACGCCGCTCGACTTGAGGTGGCGGCCTGCGGGCAGGAACCGGAAGCTCTGGATCAGATCAATGAGGGCCTGGCGCTCGCCCTCCTCAATGTAGCGCTCCGGTACGAGGGCGAGGTTGCCGTCCACGACTCGCTGTACGGTCTCGGGCCAGGATTCCATCTCACCGTTGGGCGTCTTGCGAGAGTAGGTGCGCTTGAAGACGGTCTCTGCGGTCTCGGTTGTGAACAAGGGCGTCTCCTCAGTGGGTGTCGGTGTAGGTGGTGTTCAGCATGTGCATCAGGAACGGGAAGTCCTGTCGGTCAATGTTGACCTCGAAGGACCCTTCATCGGTGTGAACGCCCAGGTAGACGGCACTGGTTCGGCCACTGTCATGGACGACTTCGATCTTGACGTCCGCGCGGGAGTGAACCTGACGGGTCTCGATCATGCGTGGACCTTCCTGCGGATCGAGCGGTTCATCTCGTACGAGAGCGCGATGACACCGCGATGGCACGCCTTCTTGTCGGCCTCGCTGCCAATCGGCAGTCCGTAGACGTAGTGCGCCATGAGGAGCTTCTGATACCGGTCGTTGAGCTTCTTCAGGCCGGCCTCGGCCTCCATGCGCGCGGTGTGAAGGTTGTCGGTGATCTCGCAGTGATTGAGCGTGTCTTTCTTGCCGATCATGTTGGCGAATTCATCCGTGGTGTAGATCAGGAGCTTGAGAGCATTCCTGGCCTCGTCCGCGGTGTAGAAATACTCGCTGTCCATAAGGTCTCGGTAGACGCGCTCGCGGGCGGCGTAGCGCTGGCCGGCCGTGTAGAAGATCTTTCGCATAAGGCGCTCGTTGTCGGCCACGGGAGCAATGTTCTTTCGCTCGCGAAGCGCGTGCTCCAGCATGGCCTGCTTCACGTCGTCGGCTTCAACGATGTGCCAGCGCTCGGCAACGACACAGGCGACTTTGCCCGCCAGGTCGGCAAGGTGCCCCCAGTCGATTGGGTTTTCCTGCATGGTTCCCTTACTTGATGGTGGTGATCTCGGACGCGTCCAGACGCTTGCTACCTCGGGACCACTTGCCGCAGCCCTCACAGCGGTAGCGCTGGAACGCGCTGACGGCCGTGTACGCCCGGCCTTCCTTCTTCAGGTCCTCGGAGCCGCAGTTGGGGCACTGGTGGTCGTCGCCCTGGCCGTCGTAGAGCTTGTGGTTGGGGTGAGTGGGAATCCACGGCAACAGGTAGTCGTAGAGGGATTCGGTGACCTTCACGTCCTGGCAGTTGTACTGCCGCATCAGGCGCCACGCCTTCTCGTCACCGGAGAGGCAGTCCACCCATAGCTGGTGGCCGGTGTGCGCGGTCTTCTTGCCGATCCCGAGCTTCTGCACCACGTAGTCGAGCTTGTTGCTCGGGAAACGGAACTGACGCTTGACGACCTTGAGTAGATCGACCTGGGCGAAGGGGGCCGGAGGAGCGAGGCCGGCCTCAAGGAACTCCCGGTTGAGGTGAGGTATGTCGAACCGCTGTCCGTTGAAGTGGACAACCGCGTCTGCCTCTTCGAGGAGAGCGTGAGCGGCCTGGATCATCGCTGCCTTGCCGTGTTGGTGGGCGCTGTAGAACATGACGTTCTTCGCGTCGTACCACTTGGCCGCGAAGCAGATGACTTCACCGGACTCAAGGAGCTGATTCATCCCGACGTTCTGATTCCAAAGCCCCCAGACGTGGGCCAGATTGGGGGAGGTCTCCAGGTCGATGGTCAGAATCTTCATGCGGTCTCCACTCGGATGTTGGCGATGTATTTCTCGGCGTACCAAATGAGCTTCTTCAGGTCCTCTGAACCGCCGTCCTGGTGCTTGTGCTGGCACCGCAGAAGGTATTTAGTCATGTTGCCGAGCAGGTATCCCTGGAATCCTTCGTGGCTCATTGAGCCCTGAATGACGTCGATGACCTCGTACTTGCCCTGCATGTAGTGCGACGGGGAGTTGACCTTGTCGGGCTTCTCATAGCCCACGCGCGGCTCTGTGGTGATTTCGTAGCCGGGGAATGCGACGGTGCGGCCATCGCTGAACTTCAGGTCGTAGAAGTCGATTCCGCCCGAGTGCTGCGGGTAGCCGGCCTCGACGGTGGCCTTGGCCTGCTGCACGTAGACCGTCTGCCCTGCCTGGTACTTCATTCCAAACCGCACTTTTCTCGAAGGGCCCTGGGGCCGTGCTCGTTCACGAACTTGTTCACGTCGGACTTCTTGCCGAACTCGATGGGGACGACGTTGGGGAGCCGTTCGGCCAGCATGTGTACGAACTTCTCGCCCGGCTCGTCCCCGTCCGTGAAGGCGAAGACCACCTCGTATCCGAGGAAGGCGGGGTCGAAGTGGTCTCGCCAACCGCTGACGCCGGGGACGCCTACGGTGGGGATGTCGGCCAGCTCGGCGCTCGCAGCGTCGAACTCGCCCTCGCTGAGCCCGAGGTACCGGGACGGTTTGATGAGGGCCCTTGTGTTGTAGAGCAGGGGCTTGGAGCCGGGGAGGCTCTGGTACTTCCCGTGGCCCTCGTGCAGTTCCTCGTCCCGCCAGGTGCCGTCCGGGTGCTTGAGGCACGCCTCGGTGATGCACCGGAAGCGCAGGGTGGCCACTGCGTGCTCGCCACCGGCCGGCCTGATGTACGGGATGGCCAGGCGCCCGAGGTGCTTCTCATGTCCCGTAGCGGGGTGCTCGACGTACCCGAATCCCAGGGGAGTTGCGAGACTGGCCAAACCGCGGTGGCTGATGTACTGCTCGGCCGGGCTTCCCGGGTAGCTCTGGCTGTACCTCTGGGCTATCTCCACCAGCGAAGCGGCTTGCGGCGAACTCTTGAGCAGCACGGAATCCCACTCCTTCCTTTCGCATGATCACGTCGTAGCTGTCCTCGCTGATGTCGCAGGCGAAGCAGTGCCAGCGCTTCTTGAATGAACTAACCGATGCCGACGGGTTCTCTTCGGGGTGTTCGGGGCAGTGGATCTTCTGCCAGCCGTCCTGCTCCTTCAGACCAACCTCGGGGTAGTAGTGCCGGAAGACATCAGCGATACCCGGCTTCCACATGTCACATCCCAACCTTGACGGCGCGCTCAATACGAAGCTGCTTGATGGCGTCCACCTCCGTCTTGACCATCTCGGCGAGGGCCTGGATCGGCATGACCTGACGGAGGGCACCGGTGCGGCACTTGTAGACGACGGTGGCCGTCTCGTGGAGACCGAGCTCGGCTTCCGCCTCCAGGAGCCGGGCCAACTTGGCCAGGCCGGTCTTGCGGGTCAGGGTGACGTGGAGCCGTCCGCCGTCGTACGAGATCACTTCTTGCCGTCCTCTCGGTGGTACCGCTTGCCTATGAAGCGGATTGCTGGGGGGTCTTCCAGGTAGTCGGCCGCATTGCGGGCGACCTGGGGGTCGTTGCGCAGGCCGCGGGCGAGGAGTATCCGATTGCACCTTGCACAACAGAGGCCGCGCACGATTCCCGTGGTGTGGTCGTGGTCCACGTCGAGCCGCTTTGCCCTGGACTGCTTGCAGATGGCGCAGACGCCACCCTGGGCCGCCAGCAGCCGGGCGTAGTCGCCGGCCTCAAGGCCGTAGACGGAGACCCGGGCCTCATGCGACGCGGCGCTTCGCTTCTTCTTGTGGCACGTGGTGCAGATCCTCGCCCTGGTGGAGGTGAAGAACCTCTCCGCGCGATTCTTCTCGCATCGGAGGCAGGGTCGGTATCCGCTCTTGGGCTTCTTCATGCCCTCTTCCTCGCTGACTTCAGTGTGTCACATCCCAACTTGCGGAGCAAATTTAAATATTGTGAGTCAGAACACTTCCTCGTCCAGGTCGGTGATTTGCAGGTTGGACGTGTTCACCTCGAACGAGGCGTACGTCTCCCCAGAGGGGTCTGTGAAGCCCTCTCGATTCTTGACCGGCGAGATATGCAGGGTCCTGCCCTGCATTCCGTCCACCTCGGCATGGATGGTGAGCACGACGGAGGGGACGCGCCCGATCTTGCCCTTCACGCCATCGAGCGGGATGGGCTTGATGCCGGAGCTGTACTCGCCGACCACGTGGTGCATGGCCATCACGTGCGCGCCGGTCTCGCGCGCCATCTCATTGAAGTAGTCGCACAGCCCCTCCAAACCGAAGGTGTACTCCTCGGCGTTCGAGGAACCTCCTCCGTCAACGTTGGTGATGTTGTCAATGACAACCAGATGTGGGTAGCAGCCGAAAACTTCGCGGTAGCACTCAAGGTGCAGTTCGATGTCCTTGGGGGTGGGCCGCGCCTGGTAGTTGAACCGCAGCCACCACCTCTTCGCAAGAGCCGCCTCGTACGCAGCAAAGGAGCCGTCGTCGGCCACGAGAGCCTTCTTGACCTCACGGGCGCTGTCGCCAGTGATCATCGCCGTGGCCCTGGAGAGCTGCGTAGCAGCCGTGCTGTCCGCACTGACGTACAGCGTGGGGACGTTGGACCAGGTGGCCAGGAAGAGAGCCATGAGGCTCTTGCCGGTACCTCCGCCAGCGCAGACGACGGAGAAGTCGCCACGCCTGAACTCGACTTCGAGCTTCTGGAGTCCGCGATACGGGGAGGGGATGGGTTCGCCGGCCGCCCCCCGAACAAGGACCGACTGATTCAGACTGAACACTGCTTCACCTTCCTATGGAATGTCACATCTCAACTTCGAGAGCGAAAAGAACACGCATGGGACACATCGCAAAATCGGCAACCGAAACCTGGCTTCGCCGGGAAGTCGCCTGACTTCACGCCTTGATCCATGCTCACGATGCGCTCGGTGATCGCGTCCTGGTCTGCGTCGGCCATCTTGACCGGCCGGGAGACCCGGTGATCCTTGGCGAGGTACCAGTCGCCGTTGGTGACCTGCTCGTCCGGGTAGAGCTGATTCAGGGCCAGGCCGTACACCCACAGCTGGAATTTGCTCTTGGTGCTGCCGGTCTTCAGGTCTCGCACACGCAGGGTCTCGTCCTTATTCAGAACTACTTGGTCGATGTACCCGCGGAGCTTGACGCCCTCGAAGTCGACCTTGAAGTACATCTCGACGGCCGGGGCCTCGCCGTCCGGGCGCCAGAGCACGGGGGCCTGATCCTGTACGTACTCGACGTACCGGCGCGTCTGCTCGGTGCCCTTGGCGAACCTGTCCTCCAAGTCGTCAGCGGCCGTGCCGCGATTCGCGCGCATCCATTGGTCGATGTCGTTGACCTTGCCCAGGTCACGATTGATGCCCTTGCTGTACTCGTCCTGGAAGACAGTGACGGCCTGGTCGGCCGTCAGCTCGCGGCCGGACTTCTCGAAGTGCTCAGCGGCCGTGTGGAACGCGGTGCCATGAGTGCTCCACGCTGCCGGCCTGGGCTCGATCCTCTCAACCCTCTTGAGCCAGCTCTTGTATGGGCACTCCTCGAACTCCGTGATCTGGGAGACGGAGCGAGGCATCAGTACCCAGCGCGTGTAGTTGGCCTCGATGGTCAT

Protein sequences of DBSCAN-SWA_1

>CP032698|2341048:2352412|2345189_2347193_-|AYG79970.1|DBSCAN-SWA
MFTTETAETVFKRTYSRKTPNGEMESWPETVQRVVDGNLALVPERYIEEGERQALIDLIQSFRFLPAGRHLKSSGVNDFALNNCWASGWVPADPAEHFRFTLLRLAEGGGVGANYSSRYFSGFSAIENRVHVHIVCDPAHPDYLDLVEAGVISTEYDYEWAGAYSVEDSREGWAGALGDLIDTAHSPDTRHENRVYDVSRVRGKGTPLRNFGGTASGPLPFAKMMVEVGKILTDAAGWPMNGMDAMAIDHQIAMAVVAGGVRRSARMSIMAWDDQLIWEFLKVKGDQLAMWTTNISVEVDDHFLTAVEDGQEHAVKVMQALAEGALKNGEPGFWNRSLTSVGEVDGTYTTNPCGEATLTPWEPCNLGSVNLGAFVRDGESDSQGLYDAHRYATRYLIRATFAKVADPKSQEAISKYRRIGVGHLGFADFLFKQGIKYSSAPYNPRVRSDLKFMAQTVDQSAAEYANELRIPVPIKKRVIAPTGTTSKLASVSGEGIHAPFAAYFLRRIRFSDLEPSEKAQVEEYRGKGYKVEPCVYGATTSVVEIPTMDPLLAAHPELADVFEHAGELSLVQMLTVQRLYQELWADQAVSYTASVDPEKYGPDDVARVMLGYMPALKGTTIFPEMSRPQTPYERISKERYLYEVAIVGEAVWDTGYDEVCASGACPI
>CP032698|2341048:2352412|2343691_2343829_-|AYG79967.1|DBSCAN-SWA
MAELVDVLAYYECACGFAFVDQYPRNATPELQAACPACETPGVNE
>CP032698|2341048:2352412|2349103_2349790_-|AYG79975.1|DBSCAN-SWA
MLLKSSPQAASLVEIAQRYSQSYPGSPAEQYISHRGLASLATPLGFGYVEHPATGHEKHLGRLAIPYIRPAGGEHAVATLRFRCITEACLKHPDGTWRDEELHEGHGKYQSLPGSKPLLYNTRALIKPSRYLGLSEGEFDAASAELADIPTVGVPGVSGWRDHFDPAFLGYEVVFAFTDGDEPGEKFVHMLAERLPNVVPIEFGKKSDVNKFVNEHGPRALREKCGLE
>CP032698|2341048:2352412|2343828_2344512_-|AYG79968.1|DBSCAN-SWA
MDVGLVQQLATDEMICMAARVSTIGRNALDRDEEKDQGLISFLLRDRHGSPFEHGSFTFRISAPIFVVREFMRHRAGMSYNEESGRYRELEPVFYVPAGERPLVQVGKAGQYDFKPGTFEQWFVASESTRTAYATAWESYQNMLAAGVAREVARSVLPVGIFSTFYVTCNPRSLMHFLSLRTKSDDAKYKSFPQVEIQMVADQMEEHFKRLMPTTHEAFVKHGRVAP
>CP032698|2341048:2352412|2351602_2352412_-|AYG79979.1|DBSCAN-SWA
MTIEANYTRWVLMPRSVSQITEFEECPYKSWLKRVERIEPRPAAWSTHGTAFHTAAEHFEKSGRELTADQAVTVFQDEYSKGINRDLGKVNDIDQWMRANRGTAADDLEDRFAKGTEQTRRYVEYVQDQAPVLWRPDGEAPAVEMYFKVDFEGVKLRGYIDQVVLNKDETLRVRDLKTGSTKSKFQLWVYGLALNQLYPDEQVTNGDWYLAKDHRVSRPVKMADADQDAITERIVSMDQGVKSGDFPAKPGFGCRFCDVSHACSFRSRS
>CP032698|2341048:2352412|2341048_2342872_-|AYG79964.1|DBSCAN-SWA
MKVINYAINGSEVRINVVETEEDLPEFRHFVINNRRALGFDTETDGLSWWEDGFRIRLAQFGNAHESYVLPTERGGLFQEDAIKAVGWIEKLAMQNGTYDILCMDRVWGVPAESVFPRLVDSRITAHLVDSRGRKDGGVGHSLEELTRHYVSATVADEVKASMTVIAKELGIKKADIWPVIPLEHEGFNLYAGMDPILAFRLVKLLKPQIPTTARKLVRYEHELAAACAYMVRRGIKADVPYIEDRAAELASTEHHYKDIAAKLGLENINSPRQVGAAVISRGVIPTETTPTGQPKVDDHLLKAHIDDPLCEAIYRGKKAAKAKATWFDNALANRDGAHRLHADIRSMGARTARMSISGAIPAQTFPSGDSLVRRGFIADPGMVICAVDYKAQELRVLAALSGDKAMKKAFREEADLHQITADAAEVDRKTGKMTNFLTVYGGGPAALMSQAGVTREVAERAIKGFFKVFPGVEQYSEDLQREARRKGYITTNTGRRLYVDKRRPYAALNYAVQSASRDVTGRAILRLLEAGYGQFMLLPVHDEVIFQFPEEHALNATTKAAQIMKEVMQGVLIDTDVSVYGKSWGCGYTADGQVCDLCNIIHKEAA
>CP032698|2341048:2352412|2343251_2343695_-|AYG79966.1|DBSCAN-SWA
MTYMWTSNAYEAGNSEIDLKNVPLSKVTIEVKEENKALIESLRKDLAEVTRKAREVEDAKRYWLKRYEDARNSARQLGEEVAKLKRDAEGTGSGHRYVRLVKHLADRKGHLERIKADAAREMAWEEGLGAEERLNEVTAALGAAGVR
>CP032698|2341048:2352412|2347203_2347392_-|AYG79971.1|DBSCAN-SWA
MIETRQVHSRADVKIEVVHDSGRTSAVYLGVHTDEGSFEVNIDRQDFPFLMHMLNTTYTDTH
>CP032698|2341048:2352412|2350008_2350257_-|AYG79976.1|DBSCAN-SWA
MISYDGGRLHVTLTRKTGLAKLARLLEAEAELGLHETATVVYKCRTGALRQVMPIQALAEMVKTEVDAIKQLRIERAVKVGM
>CP032698|2341048:2352412|2347388_2347952_-|AYG79972.1|DBSCAN-SWA
MQENPIDWGHLADLAGKVACVVAERWHIVEADDVKQAMLEHALRERKNIAPVADNERLMRKIFYTAGQRYAARERVYRDLMDSEYFYTADEARNALKLLIYTTDEFANMIGKKDTLNHCEITDNLHTARMEAEAGLKKLNDRYQKLLMAHYVYGLPIGSEADKKACHRGVIALSYEMNRSIRRKVHA
>CP032698|2341048:2352412|2350748_2351573_-|AYG79978.1|DBSCAN-SWA
MFSLNQSVLVRGAAGEPIPSPYRGLQKLEVEFRRGDFSVVCAGGGTGKSLMALFLATWSNVPTLYVSADSTAATQLSRATAMITGDSAREVKKALVADDGSFAAYEAALAKRWWLRFNYQARPTPKDIELHLECYREVFGCYPHLVVIDNITNVDGGGSSNAEEYTFGLEGLCDYFNEMARETGAHVMAMHHVVGEYSSGIKPIPLDGVKGKIGRVPSVVLTIHAEVDGMQGRTLHISPVKNREGFTDPSGETYASFEVNTSNLQITDLDEEVF
>CP032698|2341048:2352412|2344611_2345130_-|AYG79969.1|DBSCAN-SWA
MSENPFGSSPWGEPTTDTTTAETPKESPMTTPTTHTQEGVTLSFKGGEGYDASLLVLRAATVADMDAMLDEEASALASLMKRMAKIQKYSTELNAKDKGAKPAGKNSFSGGKVQNSGGDGGHQGVTDCEHGRTHVAKGTWEAYFCNADERKGDDKCAPAFLNKKSGKFELKN
>CP032698|2341048:2352412|2342909_2343137_-|AYG79965.1|DBSCAN-SWA
MLGKKANQIRLLRLEVEMANRTNAHFQKVNNRLNTYIDGLEAELDIAVQEYTELEARYDALTAEREASQADKPPF
>CP032698|2341048:2352412|2350253_2350682_-|AYG79977.1|DBSCAN-SWA
MKKPKSGYRPCLRCEKNRAERFFTSTRARICTTCHKKKRSAASHEARVSVYGLEAGDYARLLAAQGGVCAICKQSRAKRLDVDHDHTTGIVRGLCCARCNRILLARGLRNDPQVARNAADYLEDPPAIRFIGKRYHREDGKK
>CP032698|2341048:2352412|2347959_2348703_-|AYG79973.1|DBSCAN-SWA
MKILTIDLETSPNLAHVWGLWNQNVGMNQLLESGEVICFAAKWYDAKNVMFYSAHQHGKAAMIQAAHALLEEADAVVHFNGQRFDIPHLNREFLEAGLAPPAPFAQVDLLKVVKRQFRFPSNKLDYVVQKLGIGKKTAHTGHQLWVDCLSGDEKAWRLMRQYNCQDVKVTESLYDYLLPWIPTHPNHKLYDGQGDDHQCPNCGSEDLKKEGRAYTAVSAFQRYRCEGCGKWSRGSKRLDASEITTIK
>CP032698|2341048:2352412|2348699_2349107_-|AYG79974.1|DBSCAN-SWA
MKYQAGQTVYVQQAKATVEAGYPQHSGGIDFYDLKFSDGRTVAFPGYEITTEPRVGYEKPDKVNSPSHYMQGKYEVIDVIQGSMSHEGFQGYLLGNMTKYLLRCQHKHQDGGSEDLKKLIWYAEKYIANIRVETA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYG79964.1|2341048_2342872_-	DNA polymerase I, thermostable	U5P015	Mycobacterium_phage	3.3e-161	51.8
AYG79965.1|2342909_2343137_-	hypothetical protein	NA	NA	NA	NA
AYG79966.1|2343251_2343695_-	hypothetical protein	NA	NA	NA	NA
AYG79967.1|2343691_2343829_-	hypothetical protein	NA	NA	NA	NA
AYG79968.1|2343828_2344512_-	Flavin-dependent thymidylate synthase	A0A291AWC9	Streptomyces_phage	2.2e-73	62.4
AYG79969.1|2344611_2345130_-	hypothetical protein	NA	NA	NA	NA
AYG79970.1|2345189_2347193_-	Adenosylcobalamin-dependent ribonucleoside-triphosphate reductase	A0A0K2CMW0	Mycobacterium_phage	2.2e-206	55.1
AYG79971.1|2347203_2347392_-	hypothetical protein	NA	NA	NA	NA
AYG79972.1|2347388_2347952_-	hypothetical protein	NA	NA	NA	NA
AYG79973.1|2347959_2348703_-	hypothetical protein	A0A218M3B5	Acidovorax_phage	6.3e-82	54.3
AYG79974.1|2348699_2349107_-	hypothetical protein	E5DV94	Deep-sea_thermophilic_phage	1.0e-09	49.3
AYG79975.1|2349103_2349790_-	hypothetical protein	A0A0F6YPZ8	Mycobacterium_phage	4.5e-42	45.9
AYG79976.1|2350008_2350257_-	hypothetical protein	NA	NA	NA	NA
AYG79977.1|2350253_2350682_-	hypothetical protein	A0A0N6WN49	Mycobacterium_phage	2.3e-20	42.5
AYG79978.1|2350748_2351573_-	hypothetical protein	Q1A0E6	Mycobacterium_virus	1.2e-57	45.9
AYG79979.1|2351602_2352412_-	hypothetical protein	A0A286MQ86	Mycobacterium_phage	1.3e-45	39.1

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>CP032698|5286774:5353693|DBSCAN-SWA
CATGTCGGGTCCGGACCTCTGTCCCAGGCCCCGCGGGCTGCGCCGCGGGGCGGCTCTGACATTGGTGTTCGCGAGCGTCCTGGTGACCGCGGCCGCCACCAACTGTCTGCCGCGCGCCGAGCCGCACCCCGCCACGCCGGCGGCAGGACCGGCGGCGGCCGCCGCCCTCGACCCGCGCGAGGGCCACACCACCCGCGGCGGCGACCGCACCGCCGACGAGGTGCGGCGCGCGGCCGCCGAGGCCCAGGCCGACGGAGAGTCCGCCACCCGGGCCGCCGAGGAGGTCGTCGGCCGCAGCGGGGACCGCTGGGGAGCGGTGTACGACAAGGCGGAGTACGAGCAGTACGCGGACGCCCTGGAGGGCCGCTACACCGGTGTCGGCCTGTGGGTGGCCCGCGCGGCCGGCGGCCACATCCAGGTGACCCGGGTGCAGCCCGGCGGTCCCGCCGCCCGGGCCGGAGTGCGCGCCGGCGACGTGCTGCGCACCATCGACGGCTGGTCCGCCGACGGGAAGCCGGTCACCGACGTGGTCGCGCGGCTGCGCGGCGACGCGGCCGGCAGCAAGGTCGCCATCGGCCTCGGGCGGGGCCCGCTCACCTGGACCCGCACGCTGGACCGGGCGGTCCTCGGCACCGAGGACGTGGCCGTCGAGAACCTCTCCGACACGGTCGTGATGATCCGGGTGACGGCCTTCACCAAGGGCTCGGGCGAGCGGGTGCGCGCCGCGGTGCGCCGGGCCCCGGCGGGCGCCGGGATCCTGCTCGACCTGCGGGGCAACAGCGGCGGCCTGGTCGCCGAGGCCGTCACCGCGGCCTCCGCCTTCCTGCCCGGCGGCCTGGTCGCCACGTACGACGTGCACGGCAAGCAGCGCGCGCTGTACGCGAGCGGCGGCGGGGACGCCGCGCGGCCCCTGGTGGTGGTGATCGACGGCGGCACCATGAGCGCCGCCGAGCTCCTGACCGGCGCGCTCCAGGACCGGGGCCGCGCGGTCACCGTGGGCTCGCGCACCTTCGGCAAGGGCTCGGTCCAGATGCCCACCGGCCTGGTCGGCGGCTCGGTCGCCGAGCTGACCGTGGGCCACTACCGCACCCCCTCGGGCCACGGGCTCGACGGCAAGGGCATCACCCCCGACCTGCCGGTCACCGAGCACCCCCTGGAGCACGCCAGGACCGTCCTGAGCGGACTGGGCGGCACGTCGTAAACCGCTTGCGCCGAGGTGCGAAAATGGCCGCACTATGGCTAAGAACACGGGCAAGGACAAAGAGAAGGACAGCAAGCGCAAGCTGGTCGCGCAGAACAAGAAGGCACGGCACGACTACCTCATCATCGACACCTACGAGTGCGGTCTGGTGCTCACCGGCACCGAGGTGAAGTCGCTGCGCCAGGGCCGCGCCTCGCTGGTCGACGGGTTCGTCCAGATCGACGGTGGCGAGGCCTGGCTGCACAACGTGCACGTACCGGAGTACGCGCAGGGCACCTGGACCAACCACAGCGCCCGGCGCAAGCGAAAGCTGCTGCTGCACCGGATGGAGATCAACAAGCTGGAGTCGAAGTCCAGCGAGTCGGGTCACACGATCGTGCCGCTCGCCCTGTACTTCAAGGACGGCCGGGCCAAGATCGAGATCGCGCTCGCCAAGGGCAAGAAGGAGTACGACAAGCGCCAGACGCTGCGCGAGAAGCAGGACCGCCGCGAGACGGACCGTGCCATCTCGGCGGTCAAGCGCAAGGAGCGGGCGAGCCTGCGCCAGGCCCGACCGGAATAGGCTGGCACCCTCGGGCGTTGGTCACGTACGATGGCACTGCACCTCGCGAAGGTGTGGCACCACCTTGAAAAAACAACATGGGGATGATCGGTTTCGACAGCGGATGTCGAAGCAGGGGAAGCGTGTCGAGGAAGCGGCAATGATCTCGTAAACCATATGTCGCAAACAATAATCGCCAACACCAAGCGCGATTCCTTCGCCCTCGCTGCCTAAGTAGCGACGCGTGAAGTGTCAGCCCGGGGCTGTTCCCGACCCGGATCCTGGCATCAGCTAGGGAACTAAACTTCCAAGCCCGGTCACGGGGTTTGGGAGGAAATCAAACAGTGGCTGGGCCCGTCGGCGACTTGTTCGCGTGATTGCCGGGGCCGAGAAAATCGCAGCGAACTGCACACGGAGAAGCCCTGTTTTTGCACCGTTGGACGCGGGTTCGATTCCCGCCATCTCCACCGTCGAGGAAACCCGGATTTCCGGGATTCCTCGCCCCATGTGGGCACGGGCCCGGTCGCTTTCGAGTGGCCGGGCCTTTGTCATGCCCGGATGTCCGGACGTCGTAGGCCCGGACGCCCGGATGCCCGAATGTCGTAGGCCGGGATGCCGGGATGCCGGTGGGGGGCCGGGGGTCAGGCGACCCGCCGGCCGGTCAGCATGGCGAGGTCCCGGCCGGGCAGCATGGCGAGGTCATGCTCAAGCGGAAGGGGGCGCCGATTATCGGCGGGCTGGTGCGCCGTACCGTCCGCGACCGGCGGCCCCCAGCAGCAGGGCGGTGGCCGCCGCGCAGAGCGGGACCACGTAGCCCGTCTCCGGGCCCGCATGCTCGATGACCTGGCCGCCGAGCGCCGAACCGGCCGCGATGCCGCCGAGGATCGCGGTGACGGCCAGGGTCATGCCCTCGTTCAACTGCCCCTGGGGGGTGCGGCGCTGGACCAGCGTCATGCCGGTGACCATGGTGGGCGCGGTCGCCGCGCCCGCGAGGAGCAGCGCGCCCCCGAGCGCGAACAGCGAGCCGATGGCCCGTGCCGCGAGCAGCGGCAGCCACATCAGCGCGGTCATCGCCGCGAGGCAGCCGACGAGTCGCCGGGCCGTGTCGCGGGCCGGGCGCGCCGACCCGTACAGGAGTCCGGCGACACAGGACCCGGCGGCCTGGAGGGCCAGCACCGCGCCCGCCGCCGCGCGGTGCCCGAGCGCGTCGGCGTAGGCGATGGTCACCACCTCCAGCGAGCCGAAGACCGCCCCGGTGGCGAGGAAGACCGCGAGCAGCGGGGCGAACCCCCGTGCCCGGACAGGGGACTTGGCGGCCGGTGCCCGGGGTGTGGCGGGCGGCTCGGTGGCGTGCTGGGCGGCGAAGATCAGGACGCCCGTCATCAGAAGCACCGCGCCGACGAGGGTGCCGGCCTCGGGGAACAGGGCCGAGCAGAGGAACGCGGCGGCGACCGGGCCGAGCATGAAGCACAGCTCGTCCGCCGCCTGCTCGAAGGAGTTGGCGGTGTGCAGGGCCGCCGCGTCCGCCGCGGAGGGGCCTCCGTGCAGATGGGCCCAGCGGGCGCGGGACATGCCGCCGGTGTTGGGGGTGGTGGCGGTCGCGGCGTAGGCGGCGAACAGGGTCCAGTCGGGGGCGTCGAGGCGGACGCACAGGAGCAGGGCGAGCGATCCGCAGACCGCGATCGCCGTGGTCGGTACGGCTGTTCGGGCTTGGCCGTACCGGTCGACGAGCCGGGCGGTCCACGGCGCGACCAGTGCGGTCGCGGCCAGCCCGGTGGCGGTGACGGCCCCGGCCAGGGCGTAGGAGCCGCGCGCCCCCGCGATCATGATCACGGCGCTGACGCCGAACATCCCCATGGGGAGCCGGGCGACGAGGTTGCCCAGGGTGAAGGCGCGGGCGCCCGGGGTGGCGAAGAGGCGAAGGTAGGGGTTCCGGGGGCGGGCTAGCGGGGTCGGGTGCGGCATGCACCGATCCTCGTGGGGCCCGTCGCGAGGGGTCCAACACCTGATCAGCGCCCATTCACGCACTCTTGTTGTGAGCGTCGGCGGTGGTGTTGACTGCCGCCCGTGCCCCACGACACCGACCCGCGCCTGCTGCGGGCCTTCGCCGCCGTCGCCGAGGAGCTCCACTTCACTCGCGCCGCGGCCCGCCTCTTCGTCGCGCAGCAGGCCCTGAGCCGTGACATTCGGCGCCTGGAGCGGGAGTTGGGGGCCGAACTCTTCGTGCGCACCACCCGGGCCGTGACGCTCACGGCGGACGGGACGCGACTGCTGCCGTACGCCCGGCGGGTGCTGGCCGCGCACGACGAGTTCCGGGACGCATGGGCGGCCCGGGGCGCCGAGCGGCCGCTGCTCGTCGACGTCTCGGCGCCCGTCGGCACGGGAGCGCGGGTGCTCGCCGAGGCCCGCGCCCAGGCACCCGGGGTCGAGTTCGTGGCCCGGTTCATCAGCGGCCTGACGGGGGCCGCCGCCGACATCCTGGCGGGCCGGCTCGACGTCTCCTTCGGCCGGGTCGCCGGGCTCGACCCGGCGGTCCTCGCGGGGCTCGCCCATCAGCCGGTGCGCTACGAGCGGATGGCGGTGCTGCTCGACGCCGGGCACCGGCTCGCGGGCCTGGCCGAGGTGCCGCTGGACGCGCTGGCCGGCGAGACGCTGTACGTTGCGGCGGGCAACCGGGCCACGGCCGAGTGGACCGACCTGGCCGAGCGGCTCTTCGCGGGACGCGGCATCGAGGCGGCCGCGCCGTTCCCGGAGATCGCGGGCGAGGAGGAGTTCGTCCGGGTGGTGCGCAAACGGGGCTGGTCGGTGCTGGCCAGCACCGAGTTCATGGACGTCCCCGGCATGGTGGTGCGCCCGCTGACCGGGCCCGTACCGCTGGCGCCGGTGTCCCTGGTCTGGCGCGACGGGCTCACGCATCCCGGGCTCGATGTCCTGCGACGGGTCGCGCGTGAACAGGCGGCGGCGCACGGGTGGCTGGAAAGGCCCGCTGGAAGCTGGCTTCCCGAGCCCGACATGTCCCTGATGGTGGTCAATGCCCCGCGTGTGGGCCGCATAAGGCGAAGCTCACGCGATACGTGAACACATGTCCACAGCCTCGTGCGCTACATTCATCGCCCGGGTGCGGCGGGATAGGGGGGCACTCCGAACGGGTGGGTTTTCCCCGTTCCGGAGGTGGTGCCCGGGAGTCGTGCGCGCAACCCGCGAAACACATTCAGGGAGTGCGTACGAACATGGACAGTCGGATAACCAGCGGACCGGACGGACAGTCCCGTTCCGGTCAGTCGGCGGATCGCCGGACCTCGCCCGACGTGACGATGCAACTGAGCTTCCGCGCGCAGGAGTTGAACGTGCCCCGGCCCCGTCCGGAGCCCGCACCGGCACCATCGCCCGCAGCCGCGCCCGCACCCACAGCAGAGCCCGCCCCCGCGCCCGAGGCCGCACCCGCACGGGCAGCCGCACCCGCATCCGCCCCCGCGTCCGAGGCCGCACGGGCAGCCGGGGCCTCACGGGCACCCGCACCCGCAACCGCACCAGCAACCGCGCCCTCCCGCGCGCCCGAAGGCACAGCCGTCCCCGCACCCATGCCCGCGTCCAAGGCCGCACCCGAGCGGGCAGCCGCCCCCGCGTCCAAGGCCGCACCCGCACGGGCAGCCGCACCCGCGCCCGAGCGGACGCCCGCGCCCGCGCGGACCGCCGCCCCCGAGCCCGTGCTGTGGTCCGCCACGCAGGAGATCCCGGTCTTCAACCCGCTGCCCGCCATACCGACCCAGCAGGGCCACGACAAGCCCGTGTTCGTCGACGTCAGCGGACGGCGCGGCAAGAAGCTGCGCCGGCTCGGCTGGCTCTGCGGACTGGCCGCCACCGGCTTCGCCGTGGCGCTCGTCGGCTCCCTGCTCGGCGGCAACTCCCGGGCCCCCGGCCTGACCCTGCCCGACGCCACCAAGGACGACGCCGTGACGGCCCCGCCGCGGGCGACCGCCTCGCAGGTCCCGCAGCCGAAGCAGTCCCCGAAGAAGCTCGTGGTCCCGTCCCACGGCGTGTCCAAGGCGCCCGCGTCCAAGACGGTCAAGCCCTCCAAGGCCTCGCACGGCGCCACCCCCGTCACCGGGCACAGCCCCGTGAACACCAAGGTCTCCCCGCGCCCGAGCGCCTCGAAGAAGCCGGTCACGCGCGCGGTCACCCCCACCGCCGCCAAGACCGGCGCCTAGCGCGACCGCCCGCTCCACCCGGCCCGCCCGCAGGGGCCCGGACAGCGCCCCCCAGCACCCCGAGCACCCTGAGCACCAACCCCGTACGGCCACCCCGGCGTACCGGCCCGAAGGCGTAACGACACCTGTCATGACAACCACCCAGGCCAAGCCGCGGCCGACGCGGCGCAAGCGGCTGCCCATGCGCTACCTGCTGCCGCTGCTGCTCCTCGTCGCGCTCGTCGCGATGCTGATGCTGCGCGGCTATGTGCACAGCGAGATCTCCGCGGACCACCGGGTCCGCGACCCCGCGCCCACCGACCGGGTGCCCGAGTCGATCATCGACGGCGGCCCGGTCATCGACGCACGCACCCCGGGCAAGCCGGTCAGCCTCCAGATCCCGGACCACAGAATCGTCCTCACCTTCGACGACGGCCCGGACCCCACCTGGACGCCGAAGGTCCTGGACGAACTGAAGAAGCACCACGCGCACGCCGTCTTCTTCGTCACCGGAACCAACGCCTCGCGCTACCCCGACCTCATCAAGCGCATGGTCGCCGAGGGCCACGAGGTGGGCCTGCACACCTTCAACCACCCCGATCTCTCCTACCAGTCGAAGGCGCGGATCGACCGGGAGCTCTCCGAGAACCAGCTCGCGCTGGCCGGCGCCGCGGGGGTGCACAGCTCGCTGTTCCGGCCGCCGTACTCCTCGTTCGCCGACGCCATGGACAACGACACCTGGCCGGTCGTCCAGTACGTCGGCAGCAAGGGCTATGTCGTGGCGCTGGACTCCACCGACAGCGAGGACTGGCAGCGTCCGGGCGTCAAGAAGATCATCCACAACGCCACCCCCGAGGACGACAAGGGCGCCATCGTCCTGATGCACGACTTCGGTGGCGACCGCTCGCAGACCGTGGCCGCGCTCGACCAATTCCTGCCGGACATGCAGGAGTCGGGCTACACCTTCGTCAACCTCACCACCGCGCTCGGCGCGCCCAGCGCCCTGACCCCGGTCAGCGGAATGGACCTGTGGAAGGGGCAGGCGTTCGTCGGCGCCGTTCAGGTCGCCGAACACACCACCGACTTCCTGGTCGTCGGCCTCGCCGTCATCGGCGTGCTCGTGTTCACCCGCTTCGGGCTGATGCTGGTCCTCTCCTTCGCCCACGCCCGCAAGGTGCGCCGCAAGGACTTCAGCTGGGGCCCGCCGGTCACCGAACCGGTCTCGGTGCTCGTGCCCGCGTACAACGAACGCGAATGCATCGCCAACACCGTTCGTTCGCTCATGGCGAGCGATCATCCGATCGAAGTGATCGTCATCGATGACGGTTCGAGCGACGGCACCGCCGACATCGTCGAGGCGCTCGGCCTTCCCAACGTCCGCGTGGTGCGCCAGGAGAACGCCGGCAAGCCCGCCGCCCTCAACAACGGGATCGCGCACGCCCGTTACGAGCTCGTCGTGATGATGGACGGCGACACCGTCTTCGAACCCGGCACCGTCCGTGAACTCGTCCAGCCCTTCGGCAGCTCCCGCGTCGGCGCCGTCGCCGGCAACGCCAAGGTCGGCAACCGCAACTCGCTCATCGGCGCCTGGCAGCACATCGAGTACGTGATGGGCTTCAACCTCGACCGCCGCATGTACGACCTGATGGGCATCATGCCCACCATCCCCGGCGCGGTCGGCGCCTTCCGCCGCCAGGCCCTGGAGCGGGTCGGCGGCATGAGCGAGGACACCCTCGCCGAGGACACCGACATCACCATGGCCATCCACCGCGACGGCTGGCGCGTCGTCTACGCCGAGAACGCCCGCGCCTGGACCGAGGCCCCCGAGTCCGTCCAGCAGCTCTGGTCGCAGCGCTACCGCTGGTCGTACGGCACCATGCAGGCGATCTGGAAGCACCGCGGCGCCATCAAGGACCGCGGCGCCTCCGGCCGCTTCGGCCGCGTGGGCCTGCCGCTGGTCGCCCTGTTCATGGTGGTGGCCCCGCTGCTCGCCCCGCTCATCGACATCTTCCTGCTGTACGGAATCGTCTTCGGCAAGTCCCAACAGACGGTCCTGGCCTGGCTCGGCGTCCTGCTGATCCAAGCGGTGTGCGCGGCCTACGCCTTCCGGCTCGACAAGGAACGGCTCACCCATCTGCTGTCCCTGCCGCTCCAACAGGTCCTGTACCGGCAGTTGATGTACGTCGTGCTGCTCCAGTCCTGGATCACCGCGGTGACCGGCGGCCGGCTGCGCTGGCAGAAGCTGCGCCGCACCGGCGTCGTCGAGGCGCCCGGCAACCCCGCCGAACGGAAGGCCGCCGGATGACCTCCTACGTCAACGTGCCCGAGGCGGCGGCCACCCCCGCCGCGCCGCCGCCCCGGCCGCCCGCGCGCGACCGGTACTTCGACTTCCTGCGCGGCCTCGCCCTGTTCCGGGTGGTGCTCTACCACCTGATGGGCTGGGCCTGGCTGCCGCTCGCCTTCCCCTCCATGGGCGTGATGTTCGCGCTCGCCGGAAACCTGATGGCCCGCTCCCTCAAGCGGCCCGCCGTCCAGGTCGTACGCGGCCGGCTGCGGCGGCTGCTGCCCCCGATGTGGCTGCTCGGCGCGGTCGGCATCACCGGGATGCTCGCCCAGGGCTGGGGCCCCGACTCCGACGGGCACCCCGCCTGGTGGTGGGGGCATCTGCTGTTCTGGGTGGTGCCGCTCAGCGATCCGCCGTACGCGGCCGACCTGCCGGGCATCCACCACGTACTCGGCGACAACTGGGGCGCCAACCTCGCCGAACCGCTCTGGTACCTGCGCGCCTACCTGTGGTTCGTGCTGCTCTCGCCGCTCTTCAGGGCGCTGCTGCGCAAGCTGCCCTGGCCGACGATCATCGCCCCGGTCGCGCTCTGTGCGCTCCTGGAGTTCGCCGACCTCGGGCTGCCCGAGCGGATCGACTCCGCGCTCACCGACTTCGCCACCTTCGGCGCCTGCTGGATCCTCGGCATGGCCCACCAGGCGGGCGTCCTGCGCAAGCTCCCCGGCTATCTGGTGCCCTCGCTCGCCCCCCTGGTGATGGCGCTCGGCTACTGGTGGGCGGTGCACGGCGGGTACTCCCTCACGGGCGACACCGAACTCGACGCGATCCCGCTCGCCCAAGCCCTGTGGTCGCTCGGCGCGGTGCTCCTGCTGCTCCACATCAGCCCCTCGTGGGAGACCTGGCCCGACCCGCTGCGCCGCTGGGACCGGCTGATCACCCTGCTCAACTCCCGCGCCGTGACCATCTATCTCTGGCACAACCTGTGCATCCTGGTCGCCGCCACCGTCTGGGACGACCTGTGGAGCGTCGACGCCCTCGCGGGCGCCGCCCCCTTCCTCAACAGCTCCTGGCCGGTCCTCGTGGTGACCTGGCTCCTCATCGGCGTGTGCGTGGGGTGCTTCGGCTGGGTCGAGGACGTGGCGGCCAAGCGCCGCCCCCGCCTCTGGCCCGTCTGAGCCGCCCGGTCGGCGGCGGTCTCACCGCCGCCGACCGCACCCCGTGAAGACACGGTTGCACCCCGGTCACCCGGCGGCACGCGGCCGAAACCCGCTCTCCCTACGGTCGCTGCCACAGGAAGCGAACCGACCGTGGAGGCAAGATGACGGGCCGTTGGATCGATCGGTGGGAGCCGGAGGACGACACCTTCTGGCGGGAGACGGGACGGCGCGTCGCCCGGCGGAACCTGTTCCTCTCCGTGTTCTGCGAACACGTCGGGTTCTCCATCTGGAGCCTGTGGTCGGTGATGGTCCTCTTCATGGGCCCCGCCTACGGAGTGGACCCCGCGGGCAAGTTCTTCCTCATCTCGGTGGCGACGCTCGTCGGCGCCCTCGTCCGCATCCCCTACACCTTCGCCGTGGCCCGCTTCGGCGGCCGCAACTGGAGCGTCTTCAGCGCCCTGCTGCTCCTGGTCCCGGCCGGCGCCGCCTGGTTCGCGATGGAGCCCGGCACCTCGTACAGCACGTTCCTGCTGGTCTCCGCCCTCGCCGGGGTGGGCGGCGGCAACTTCGCGTCCTCGATGACCAACATCAACGCCTTCTTCCCGCTGCGCGAGAAGGGCTGGGCGCTCGGCCTGAACGCGGGCGGCGGCAACATCGGCGTCCCCGTCGTCCAGCTCGTCGGGCTGCTGGTCATCGCGACCGCCGGGGCCACCCACCCGCGCATCGTGCTCGCCGTCTACCTGCCGCTGATCGCCCTCGCCGGGCTGGGGGCCGCGCTCGGGATGGACAACCTGGCGCCCGTACGCAACGACACCGGCGCGGTCGGTGAGGCGCTGCGCGAGGCGCACACCTGGATCATGGCGTTCCTCTACGTCGGCACGTTCGGCTCGTTCATCGGCTACAGCTTCGCCTTCGGCCTGGTGCTCCAGACCCAGTTCGGGCGGACCCCGCTCCAGGCGGCCTCGCTCACCTTCATCGGGCCGCTGCTCGGCTCCCTTATCCGGCCCGTCGGCGGACGCCTCGCCGACCGCCACGGCGGCGCCCGCATCACGCTGGTGAACTTCGCCGCGATGGCGGTGGCCACCTGTGTCGTCCTGTACGCCTCCGCGCAGAAGTCGCTGCCCGTCTTCCTCACCGGGTTCATCGCCCTGTTCGCGCTCGGCGGGCTCGGCAACGGCTCCACCTTCAAGATGATCCCCGGCATCTTCCAGGCCAAGGCGCTCGCCCGCGGTCTGGCCCCCCAGGCCGCGGCGGCCTACGGACGGCGCCTGTCGGGGGCGGCCATGGGTCTGGTCGGCGCGATCGGTGCGCTCGGCGGCCTCGCGATCAACCTCGCCTTCCGCCAGTCCTTCGGGACCACCGGCACCGGCACCACCGCCTATGCCGCCTTCCTCGCCTGTTACGCGGCGTGTTTCACGGTGACGTGGGCGGTATACATCCGCCGGCCCGCCGAAGCCGGCGTGCCCGCCACGGCCCCGCCCGCCGCCGTCGAGGTGTGATCCCGGCCGCACCAGGGGGACGTAACACCCGGGAAACCACCAGGAACCCCGGGCGTCACGCCCCCTTGGCAGGCTCGGACGCCACCGCACCACCGGGAGAGTCATGTCCGCAGAACCAGAAGTGGCCGCACCGCACGGGCCGCACGGGCCGGGCGGGCCCCTCGACGGGTTCACCGTCGGCGTCACCGCCGCCCGCCGCGCCGACGAGCTCGCGACGCTGCTCACCCGGCGCGGGGCAGCCGTCCTGCACGCGCCCGCGCTGCGGATCGTGCCGCTCGCCGATGACAGCGAACTCCTCGCCGCCACCCGGGAGTTGATCACCAAGGCGCCCGACACGGTGGTCGCCACCACCGCCATCGGGTTCCGCGGCTGGGTCGAGGCCGCCGACGGCTGGGGGATAGGGGACGCCCTCCTCAAGACCCTCAAAGGCGTCGAACTCCTGGCGCGCGGCCCCAAGGTCAAGGGCGCGGTGCGGGCCGCCGGGCTCACCGAGCGGTGGTCGCCGTCGTCGGAGTCGATGGCCGAGGTCCTCGACCGGCTGCTCGCCGAGGGCGTGGCGGGCCGGCGCATCGCGATCCAGCTGCACGGCGAACCCCTGCCGGGCTTCGTGGAGGCGCTGCGGGCCGGCGGCGCCGAGATCGTCGGGGTCCCCGTCTACCGCTGGCTGCCGCCGCAGGACCCGGCGCCCCTCGACCGGCTCCTGGACGCCACCGTCTCCCGAGGCCTGGACGCGCTCACCTTCACCAGCGCCCCGGCCGCGGCCTCGCTCCTGAACCGGGCCGAGGAACGCGGCATGCTCGCCGAGCTGCTGCTCGCCCTGCGCGACGACGTATTGACCGCCTGCGTCGGCCCGGTCACCGCGCTGCCGCTCCAGGCCCGCGGCGTACACACCCTCGCCCCCGAACGCTTCCGTCTGGGGCCGCTCGTCCAGCTCCTGTGCGCCGAACTCCCTTCCCGGGCACGAGTCTTGCCGCTGGCCGGGCGGCGGGTCGAGATCCGGGGGCACGCCGTGCTCGTGGACGGAGCGCTGCGCCCGGTGCCCCCGGCCGGCATGGCCCTGCTGCGCACCCTGGCCCGCCGCCCCGGCTGGGTGGTCTCCCGCGCCGAGCTGCTGCGCGCCCTGCCGGGCTCGGGCACCGACGAGCACGCCGTGGAGACCGCGATGGCCCGGCTGCGTACGGCGCTGGGCGCGCCCCGCGTCATCCAGACCGTGGTCAAGCGCGGCTACCGACTGGCACTCGACCCGGCCGCCGACGCGAAATACGCGGACGACGCGGACTGAGCCGCCCCAGACAGGCCCGCGCCAGAAAGCCCAGGGACAGCGTGCACAGCCCGGCCCGCACCGCGTTCCACGCCACCCAGGGCCCCTCGAAATGGGCACGGGCGGCCGCCGGGTCGGTGGCGCGGGCCAGGGCGTCGTTCAGGGGCACGTTCACCGCACTGGTGAGCACGAAGGCCAGGGCGTACGCGCCGAGCGCGGCATACGTCGAGCCGCGCACCCCGGGCTCGTGGCGCTGCTGCCAGGCCGCGACCGCGATCAGCACCGGCGCCCCGAGGAAGCTCGCGAAGAAGACCGGGTTCTGGATCACGTCGTTGATGTTCCGCATGACCGCGACGTAGGTGTGGTCGTCGCTGCGGGCGAGCGCGGGCATCACCGCACAGGAGAAGACGAAGAACGAACCCGCCGCGAGCCCCGTGGCCACCGTGGCCGCCCCCAGGGCCCAACTGCCGCCGCCGACCCGCATGTTGTCGTGTGTGTTCATGCCCCGAGTCAACCGCCGCCCGGGCCCCGGCGACATGGCCGCGACGCGCACCCCCATACGCGGACGTCTACGTACGCCCAGGACGACGCCGAGCCCCGCCGCCCTCCTCGGCGGGGGCCCACACCGGCCGCCCCGGTAGGAGGGCTACCGGGGGCGGCCCGCGACGGGCACTCTGGGGGGAGGCACTCACCGGTAACCCCCTAGGCGGTGACAGGCGCATGGTGCGGTTCGACTCCGGGCGGATCTGTCTGGATCTGGTGGCGACCGGAGCGCGGGAGAGCGAACAGCTGGGCCGCGTCGAGGAGTTGAGCCGCTGGCTGCTCGCCGCCGGACTCGTCCCGCGCGACACCCCCCTCGCCGGGATCGACGACGACTGGCTCGCCCGCTTCCTCGAACTACGGCGCTGCGTGAGCCAGTTGATCCACGCGGAACTGGGCGGACCCGCCGATGCGGCCCCCGCGGCCCTCGACCGCGTCAACGCGCTCGCCGCGGCCGCGCCGCCGGGCGTACGGGCCGTCAGAGGCGCGGACGGCGGCCTGGTGCGCACCCTGAGCCGGGCCCCCGAGTGCGGCGCGCTGCTCGCCGTCGTCGCACGGGACGCCGTCGACCTGCTCACCGACCCCGAGGCGAGATCCCGGCTCCGCCAGTGCGAGGGCGACAGCTGCCGGCTGCTCTACCTCGACACCTCGCGCGGGCGCCGGCGCCGCTGGTGCTCCAGCGAGGCGTGCGGAAACCGCGAACGGGTCGCCCGGCACCGGCGCCGGCTCGCCGCCCTGTGAAGGCTCCCGCGGAGAACGGGCGAAGAAAAGTCGCCCGCGTTTTGAATGGTTCCCGACAACCGCCCGTATGGAGAGACGAACCGGCTCGCAGCCGCGCGCCGGAATGGTCTCGACCTGGAGGTGCCGGTTGCGCAAGGATGCCGCCGTGGCCGATGACCGTCCGCGAGGGGCCAAGCACCGCTCCGTGCCCGACGAGGAGCTGATGCGGGCGCTGTACCGCGAGCACGCGGGGCCGCTGCTCGGGTACGTGATGCGTCTCGTCGCCGGTGACCGCCAGCGGGCCGAGGACGTCGTGCAGGAGACGCTCATCCGTGCCTGGAAGAACGCCGGTCAGCTCAATCGGGCCACCGGTTCGGTCCGCCCCTGGCTGGTGACGGTCGCGCGCCGCATCGTCATCGACGGCCACCGCAGCCGGCAGGCCCGGCCGCAGGAGGTCGATCCGTCGCCGCTGGAGGTCATGCCCGCGGAGGACGAGATCGACAAGGCGTTGTGGCTGATGACCCTCTCCGATGCACTCGACGACCTCACCCCGGCCCACCGGGAGGCACTCGTCGAGACGTACTTCAAGGGACGTACGGTCAACGAGGCGGCCCAGGCGCTCGGCGTACCCAGCGGGACCGTGCGGTCCCGGGTCTTCTACGCCCTGCGCTCCATGAAACTCGCACTGGAGGAACGGGGGGTGACGACATGACGAGCGGGGAGTACGCGCAGGGCTCGCCGCACGAGGCCGTCGGCGCGTATGTGCTCGGGGTCCTGGACGACGCCGAGGCCACCGCCTTCGAGGCCCACCTCGCGGGCTGCGAGCCGTGCGCCGCCGAACTCGACGCCCTGGCGGGCATGGAGCCGATGCTGGCCGGCCTCAAGGAGTTCCCGGGCCCCGCGGCCCAGCCCCTGCGCCCGGCGCCGCCCGATCTGTCCATGGCCCTGATCAACGAGGTCGCGGCCCAGCGGGCCCGGCGCAGGCGGCGCACCACCTATCTGGTGGCGGCCGCGGCGGCGCTGATCGTGGGCGGCCCGGCGGTCGCGGTGGTGGCGACCTCCTCGGGCACCGGCACCCACCAGAGCGCCGAGGCGCACCCGACCAGCCCGGCCGAGGATGCCTTCTTCAACCACATGACCCAGAAGACCTCCGCGACCGACCCGACGTCGGAGGTGACCGCGACCGTCGGCACCGAGCCCAAGGCCTGGGGCACCCACACGGTCCTGGAACTGAAGAACGTCAAGGGCCCGCTCAAGTGCAGCCTGATCGCGATCGGCAAGAACGGCGAACGCGAGACGGTCACCTCCTGGGCGGTGCCCAACTGGGGCTACGGCATCAAGGACAGCCCCCACGAATCGGCTCGGTACCCGCTGTACGTGCACGGCGGCACCGCGATGACCCACGACCAGATCGACCACTTCGAGGTCCGTACGTTCGACGGGAAGGCGCTCGTGGACATCCCCGCATGAGCCGCGGCGCGGCAGAACCGTCCCGACATGCGGTTCGGCACCAAATCGTGGCCTGACATCGGGCCCCCCTTCGCGTACGGTTGACGGCTGCCCAATGCACGTCAGAAGGGGGCCTCGGTGGCCGCGCAGGATGCCGCTGTCGATACCGCTTCCGGTACCGCCGAATCCACTGTGGATTCGGTCCGGGAACGCGAGATCGCTGGGGAACAGGTACATCTCGACCAGGTGTACCGCCGCCTGGAGGAGAAGATCCACGAGGCGGAGTTCCTGATGAACGACGCCGCCAAGCGGGGTCAGGTCGGCACGCCCGGCGCCCTCGCCGAACGCGACGCACAGGTGTTCCGGGCGGGGGTCCATCTCAACCGTCTCAACAACGAGTTCGAGGACTTCCTCTTCGGCCGCATCGACCTCCTGCTCGGCCAGGACGGCAAGAAGGGGCCGGACGGCGCGTACACCTCGATCGACCCGGCCGAGGACGCCGTGCGCCCGGACGGCACGGCCGACATCGCCGAAACGTTGCACATCGGCCGCATCGGCGTCCTGGACTCCGACTACTCGCCGCTGGTCATCGACTGGCGCGCGCCCGCCGCGGCGCCGTTCTACCGCTCGACCCCGGTCGACCCGGGCCGGGTCGTACGGCGGCGCGTCATCCGCTCCAAGGGCCGCAAGGTGCTCGGCGTCGAGGACGACCTGATGCGCCCCGAGCTGCGGGCGACCCTGAACGGCGCGGAGCTGCCCGTCATCGGCGACGGCGCCCTCATGGCCGCGCTCGGCCAGGCCCGCAGCCACACCATGCGGGACATCGTCGCCTCCATCCAGGCCGAGCAGGACATGGTGATCCGGGCGCCCGCGGCCTCCGTCACCTACGTCGAGGGCGGCCCCGGCACCGGCAAGACCGCCGTCGCCCTGCACCGCGCCGCCTATCTGCTCTACCAGGACCGGCGGCGCTACTCCGGCGGCATCCTGATCGTCTCGCCGACGCCGCTGCTCGTCTCGTACACCGAGGGCGTACTGCCCTCGCTCGGCGAGGAGGGCCAGGTCGCGATCCGGGCCGTCGGCAACCTCGTGGACGGCGCGGAGGCCACCGAGTACGACGACCCGGCCATCGCCCGGATCAAGGGCTCCTCCCGCATGCTGCACGTGCTGCGCCGGGCCGCCAGGGGCGCCCTGGAAGGGCCGGGGGAGCAGCAGTCCAGACGCTCCCGGCGGCGCGGCGGCGAACAGCTCGCCCTCGGCGAGCAGGCCCCGCAGCCGCACCCCGCCCAGCGGCTGCGCGTCGTCGCGTTCGGCGCGCGCATCGAGCTGGAGGGCGAGGAGCTGCGCCGCATCCGCCAGACCGTGCTCGGCGGCACCGCACCCGTCAACCTGCTGCGCCCGCGCGCCCGCCGACTGCTCCTGGACGCGCTGTGGTCGAAGTCGGCCGCGGCCGGCCGCGCCGGTGACGTCTCCCGGGGCGACCCGGAGCTCGCCGCCGAACTGCGCTCCTCCTTCGACGACGACATCACCTCCGAGGACGCCTTCATCGCCTTCCTCGACGCCTGGTGGCCCGAGCTCACCCCGCGCGGGGTGCTGGCCGCGATGGCCGACGAGAAGCGCTTGGGGCGCTGGGCGCGCCGCGTCCTGAACCAGGGCGAGGTGCGCCGCCTGGCGCGCTCGCTGGCCCGGGCAGCGGATGGCGCGTTCTCCGTGCACGACGTGGCGCTGCTGGACGAGCTGGAGACGCTGCTCGGCGCCCCGGCCCGGCCGAAGAGGAAGCGCGAGTACGATCCGCTGGACGCGCTGACGGGTCTTGAGGAGCTGATGCCGCACCGCGAGGAGACCCAGCGCGAGCGCGCGGAGCGGCTCGCCCTGGAGCGCACCGAGTACGCCCACGTCATCGTGGACGAGGCGCAGGACCTCACGCCCATGCAGTGGCGCATGGTGGGCCGGCGCGGGCGCACCGCCACCTGGACGGTGGTGGGTGACCCCGCCCAGTCCTCCTGGTCCGACCCGGACGAGGCCGCCGAGGCCCGGGACGAGGCGCTGGGCAGCCGCCCGCGCCGCCGTTTCGAGCTGACCGTCAACTACCGCAACCCGGCCGAGATCGCCGAACTGGCCGCCCGCGTCCTGGCGTTGGCGATGCCGGGCATGAAGTCCCCGGCCGCCGTCCGCTCCACCGGCGTCGAGCCCCGGTTCGCGGTCGTACGCGACGGCGACCTCGCGCGCACGGTGCGCGAGGAGGCGGCGCGGCTGCTCGACCGGGTGGACGGCACGGTCGGCGTGGTCGTCGCGATGCGCCGCCGCGAGCAGGCCGCGCGCTGGCTGGCGGAGCTCGGCGACCGGGTGGTGGCGCTGGGCAGCCTGGAGGCCAAGGGTCTGGAGTACGACGCCACGGTGGTCGTCAGCCCGGCCGAGATCGCGGACGAGTCCCCGGCCGGACTGCGGGTGCTGTACGTGGCGTTGACCCGGGCGACCCAGCAGCTCACGGTCGTCTCGGGGGACCGGGACGAGCCCGACGCGGCGGGGGTGCCGGATCTGCTCCGCGAGTAAATTCGCGGTCAACTCGCGATGCGGGGATCACTTGGCGGAGTGGTTTGTTAGCCTGGTTGTGGCACCGGCCCGATCCAAGCCCCCGGGCCCAACCTTAGTCGCTCAGAGCGACCACTTGCCGCGAGGCGAGCATGGCGGGTCGGTGTCATGAACGTGAGCGACAGGCCCACGTCATCTTCGGATGGCGTGGGCCTGTTGTCGTTGGGCGTACGGCGGTTGAGCCGTCGGTCCTTCCCGGGCGGGCTGGCCGAAGGGACTTCCGCCGGACCACCACTTTCTCGTATGGTGGAAACAACTTTCCGAAAAGGGCCGCCCATTATCGGCTACCAGCCAGTAGGTGCGACCATCGGATGGCACCGCCGCGCCACAGCCGGGGCGGTGCTAGCAACGAAGCTAGGGAAAGCAGAGGAACACGGTCATGGCAACGGCGCCCAGCGTCTCGTACTCGATGACGGTCCGCCTTGAGGTGCCCGCCAGCGGCACGGCGGTCTCCCAGCTCACCACGGCCGTGGAGTCCTCCGGCGGATCGGTGACCGGCCTCGACGTGACCGCCTCCGGCCACGAGAAGCTGCGGATCGACGTCACCATCGCGGCCACCTCCACCTCGCACGCCGACGAGATCGTCGAGGAGCTGCGCGGCATCGAGGGCGTCAGCCTCGGCAAGGTCTCCGACCGTACGTTCCTGATGCACCTCGGCGGCAAGATCGAGATGCAGTCGAAGCACCCCATCCGCAACCGTGACGACCTCTCGATGATCTACACCCCGGGCGTCGCCCGGGTGTGCATGGCGATCGCCGAGAACCCCGAGGACGCCCGGCGCCTGACCATCAAGCGCAACACCGTCGCAGTCGTGACGGACGGCTCCGCGGTGCTCGGCCTCGGCAACATCGGCCCGATGGCCGCCATGCCGGTCATGGAGGGCAAGGCGGCCCTCTTCAAGCGCTTCGCCGACATCGACGCCTGGCCGCTGTGCCTGGACACCCAGGACACCGACGAGATCGTCGCCATCGTCAAGGCGATCGCCCCCGGCTTCGCGGGCATCAACCTCGAGGACATCTCCGCGCCGCGCTGCTTCGAGATCGAGGCGCGGCTGCGCGAGGCCCTCGACATCCCCGTCTTCCACGACGACCAGCACGGCACCGCGATCGTGGTGCTGGCCTCGCTGACCAACGCGCTGCGCGTGGTGGGCAAGGGAATGGGTGACGTACGCGTCGTCATGTCCGGCGCCGGCGCGGCCGGTACCGCCATCCTGAAGCTGCTGCTCGCGGCGGGCGTCAAGAACGCCGTCGTCGCCGACATCCACGGCGTGGTGCACGCGGGGCGCGAGGACCTGGTGGACGCGAGCCCCGAGTCCGCGCTGCGCTGGATCGCCGACAACACCAACCCCGAGGGCCTCACCGGCACCCTCAAGGAGGCCGTGGTCGGCGCCGACGTCTTCATCGGGGTCTCCGCCCCCAACGTCCTCAACGGCGACGACGTCGCCGCGATGGCCGAGGGCGCGATCGTGTTCGCGCTCGCGAACCCGGACCCCGAGGTGGACCCCGCGATCGCCCGCGAGACGGCGGCGGTCGTGGCCACCGGCCGCTCGGACTTCCCCAACCAGATCAACAACGTGCTGGTCTTCCCGGGTGTCTTCCGCGGCCTGCTCGACGCCCAGTCCCGCACCGTCAACACGGACATGATGCTGGCCGCCGCGGGCGCCCTCGCGGACGTCGTCGCCGAGGACGAGCTGAACGCGAACTACATCATCCCGTCGGTCTTCAACGACAAGGTCGCCGGGGCCGTCGCCGGGGCCGTCCGCACCGCCGCCAAGGCCGCCGGAGCCGCTGTGACAGGGCCCACGTCGGCCTGAGCTCCGGCGCGTCGCGGGATGCGGGCCCAGGAACGCCCCCTTAGGGTGGCGGACCATGACCCGCATCCGCACCGGCAACCCCCCGGCACCGTCCGAGGGGGCCCTCCACGGGGGTGCGCACGGGGTCGACGGAGCGTCACCACCCTGAGGCAGGGGCGCTTTTCGTGTGACTCGGTGTGACTCGGGAGGGTGCCGGATTGGCTTTCCCGCCACAGGTGGGGGCAGGATGCTCCCCCAAGGACTTCGTCCAGGGGGGACCCCCAGGACGCGAGGTCGTGCACACGGACCCGGGTCCGGGGACTGTCCGAGTGCCCTGGCAGCATCGGCTTCGCTGTATCCAACATGCGGCTACCGCCGCGTGGCACGCCTCACAGGCAAGAAGAACACGGGAGTAAGAACATGAACCGCAGTGAGCTGGTGGCCGCGCTGGCCGACCGCGCCGAGGTGACCCGCAAGGACGCCGACGCTGTCCTCGCCGCTCTCGCCGAGACGGTCGGCGAGATCGTCGCCAAGGGCGACGAGAAGGTCACCATCCCCGGCTTCCTGACCTTCGAGCGCACCCACCGTGCCGCTCGTACCGCTCGTAACCCGCAGACCGGCGACCCGATCAACATCCCGGCCGGCTACAGCGTGAAGGTCTCCGCGGGCTCGAAGCTCAAGGAAGCCGCCAAGGGCAAGTAAGCGCCCTTTGCTCTGCAAGGTCGCTCAGCAGCAACGCTGAGGGCGGTCACCCTGATCCCGGGGTGACCGCCCTCTCGCGTACCGCGAGCCCTTTCCACGAAGTTCCCCGGGCCCCCAAACCCGCTTTCGTCTGCGGACCGTGCGGGGCTGGTCGCGCAGTTCCCCGCGCCCCCTAACTGCTTGGTGCTGGGGCACCTTCAGCCTGTCCGGCGAATGAGGACGAGCGCCCTTTAGGCGCGATCGGGGTCTGGGGCAGAGCCCCAGGGGTCTTTGGCTGCGGACCGTGCGGGGCTGGGCGCGCAGTTCCCCGCGCCCCTAGCTACTCGGTGCTGGCCCGCATCGGCCACCTCAGCCCGTCCGGCGATTGAGGACGAGCGCCGTTCAGGCGCGATACGGGGTCTGGGGCGGAGCCCCAGGGGGCTCGGCCCAGCCAACCCAGTGGGCGAAGGGGCCCGGGGTCTGGGGCGGAGCCCCGGGGGGTTAGACCAGCGAACCGTTGGGGAGTTCGACCTTCGCGCCGAGGCTTTCGAGCTTCTCCATGAAGTTCTCGTAGCCCCGGTTGATCAGATCGATCCCGTGCACCCGGGACGTCCCCTGCGCCGCCAGCGCCGCGATGAGGTACGAGAACCCACCCCGCAGGTCCGGGATGACCAGATCCGCGCCCTGGAGCTTCGTGGGCCCGCTCACGACCGCGGAGTGCAGGAAGTTGCGCTGCCCGAAGCGGCAGTCGGAACCGCCCAGGCACTCGCGGTAGAGCTGGATGTGCGCACCCATCTGGTTGAGCGCCGAGGTGAACCCGAGCCGCGACTCGTACACCGTCTCGTGGACGATGGACAGGCCGGTGGCCTGGGTGAGGGCGACGACCAGCGGCTGCTGCCAGTCCGTCTGGAAGCCGGGGTGCACGTCCGTTTCGAGCGCGATCGACTTGAGCGAGCCCCCGGGGTGCCAGAAGCGGATGCCCTCGTCGTCGATCTCGAAGGCGCCGCCGACCTTCCGGTAGGTGTTCAGGAACGTCATCATCGAGCGCTGCTGGGCGCCGCGGACGTAGATGTTGCCCTCGGTCGCCAGCGCGGCGGACGCCCACGAGGCGGCCTCCAGGCGGTCCGAGAGGGCGCGGTGGGTGTACCCGCCGAGGGTGTCGACACCGGTGACCCGGATGGTCCGGTCGGTGTCCATGGCGATGATCGCGCCCATCTTCTGCAACACGCAGATGAGGTCCTCGATCTCGGGCTCCACCGCGGCGTTGGAGAGCTCGGTCACGCCCTCCGCCAGCACGGCGGTGAGCAGCACCTGCTCGGTCGCGCCGACCGAGGGGTAGGGCAGCGTGATCTTGCAACCGCGAAGGCGCTGGGGGGCCTCCAGGTACTGGCCGTCGGCGCGCTTCTCGATGGTCGCGCCGAACTGGCGGAGCACCTCGAAGTGGAAGTCGATCGGCCGGCCGCCGATGTCGCAGCCGCCGAGGCCCGGGATGAAGGCGTGGCCCAGGCGGTGCAGCAGCGGGCCGCAGAGCAGGATCGGGATCCGCGAGGAACCCGCGTGCGCGTCGATGTCGGCGACGTTGGCGGACTCGACGTGGGACGGGTCGAGAATCAGCTCGCCCGGCTCGTCGCCGGGGCGGACGGTGACGCCGTGCAGTTGCAGCAGGCCCCGCACGACGCGTACGTCGCGGATGTCGGGCACGTTGCGCAGTCTGCTCGGGCCGCTGCCGAGAAGGGCGGCGACCATCGCCTTCGGCACGAGGTTCTTCGCGCCGCGGACGCGGATCTCGCCCTCGAGCGGGGTTCCGCCGTGGACAAGCAGTACATCGTCTGTGCCGGTCATGAATCTCGCGTTCCGGAGTGGTCGGGCAAGGGGCAGGGATAAAGGGTAAGGGGCTTTCACCCCTGCCCCATAAGGCCTGGGAGGGTTCACGAAGGTAATGACTTCGCTACAGCACGCTCCGCGCAGGGAATTCAGCACAGCGTCACGGGTCGCGGCCGGTCCCCGCGACGGCGTGGCGGACGGGTGAAACGGGCGTGCGCCCCAGTGCTGCCGTGCGCTCCCCGCCGGGCCCGCTTATGCGGGATCATGTCCGCATGACCGAGGTGTCCTCGCTCACCGGGCGGCTGCTCGTCGCCACCCCCGCGCTCGCGGATCCCAACTTCGACCGCGCGGTGGTGCTGCTCCTCGACCACGACGAGGAGGGCACGCTCGGCGTGGTCCTGAACCGCCCGACGCCGGTCGGCGTGGGCGACATCCTGGAGTCCTGGGCGGGTCTCGCGGGCGAGCCCGGCGTGGTCTTCCAGGGCGGCCCGGTCTCCCTGGACTCGGCCCTGGGGGTCGCCGTCATCCCCGGCGACGAGGGGCCGCTCGGCTGGCGCCGGGTGTATGGGGCGATCGGCCTGGTCGACCTGGAGGCGCCCCCGGAACTGCTCGCGGCGGCGCTCGGCTCGCTGCGGATCTTCGCCGGGTACGCGGGCTGGGGCCCGGGCCAGTTGGAGGACGAGCTCACCGACGGCGCCTGGTACGTGGTCGAGTCGGAGCCCGGTGACGTCTCGTCCCCGGAACCGGAGAGCCTGTGGCGGGCGGTGCTGCGCCGCCAGCGCAGCGAGCTCGCGATGGTGGCCACCTATCCGGACGACCCCTCGCTCAATTGACGGCGGTGCCGACGCGCCGCCACCCGGCGCGCTCGCCTTCAGTACCCTTGGTGGTTATGAGCACTCTTGAGCCCGAGCGCGGGGCAGGTACGGGGACCCTCGTAGAGCCGACACCCCAGGTGTCGAACGGCGACGGCGACCACGAGCGCTTCGCCCACTACGTCCAGAAGGACAAGATCATGGCGAGCGCGCTGGACGGCACGCCCGTCGTCGCGCTCTGCGGCAAGGTCTGGGTGCCGGGGCGCGACCCGAAGAAGTACCCGGTCTGCCCGATGTGCAAGGAGATCTACGAGTCCATGGGCGCCGGCGGCGACAAGGACAAGGACAAGGGCGGCAAGGACAAGAAGTAAGCCCGGAATCGAAGCGGGCCCGGGCCTGAAGTAGGCCCGGGCCTGCGGGTTCGGGTGGGCGAGGGGTTTCCTTCGCGAACGGCCCCCGGGGTGTGCGTCACGCACACCCCGGGGGCCGTTCGCATGTGCGGAGTTGTCCAGACCTCTTGCGAGCGCTTTGCCTCCGCCATAGCCTCCTCCCTGTTGTGCAGTATGCGAAACGCTCGTTGCGTATGTTGCAACGGTCATGGGGAGGATTCCCGTAGTGAAGCTCTCTGCCCGAACCGCCTTGCCGCTGGCGGCACTTGCCCTCGCCGGCCTGGCCGCCTGCGCCCCGGGGACGTCCGACAACGGCGCGAAGAGCGACGACAAGAGCGGCACCCTGAGGGTCTGGCTCTTCCAGGAGGTGAACAACGGGCCCAAACAGCACGTCGTCGACCGGGCCGTGGCCGCCTTCGAGAAGTCCCACCAGGGGGCCCAGGTCCAGGTCGAGTACATACCCGTCGAGTCCCGCGCCCAGAAGATCAAGGCCGCCTTCAACGACCCCGGCTCCGCGCCCGACCTGATCGAGTACGGCAACACGGACACGGCCGGCTATGTGAAGGACGGCGGACTCGCCGAGGTGAGCGCCGAGTTCGTCGCCTGGGACGAGGCGAAGGACACCGACCCGACCGCCAAGCAGTCCGTCACGGTCGGCGGAAAGATCTACGGCGCCCCGCTGTTCGTGGGCGTACGCGCGCTGTACTACCGCACCGACGTCCTGAAGGAGCTGGGCCTCGCCGTGCCCAGGACGCAGGACGAGCTGATCGCGACCGCCAAGAAGATCCACCAGTCGAAGCCCGACCTCTACGGGCTCGTGGTCGGCGGCGCCTACACCTACGGGGCGCTGCCGTTCCTGTGGGCCAACGGGGGAGAACTGGCCACCGAGAACGGCGGAAAATACACCTCGGCCCTCGACGCCGAGCCCGCCCGCAAGGGCATCACGGCCTACACCTCGCTCTTCGGCGACGACAACTGCCCCGCCGCCAAGTGCGCGCAGATGGGCGGCAACGCCACCGTGACCGCGTTCGCGGGCGGCAAGGCGGCCATGGCGATCGGCGGCGACTTCAACCACGCCGCCGTCGACGCCGGCGCCGTCAAGGGCAAGTACGCCGTCGTGCCGCTGCCCGGCCGGGCCCCCGGCTCCATCGCCCCGGCCTTCGCGGGCGGCAACAACATCGGCGTACTGAAGAGCAGTTCGCACCGCACGCTCGCCGTCGGCCTCATGGAGCAGCTCGCCGGAAAGGCCACCCAGCGCGAACTCTTCGACGCGATGGGCTTCCTGCCGACCTACACCGACGTACGGGCCGACGTCGCGAAGAAGCAGCCCTTCGTCGAGCCGTTCGTGCGCACCCTGGCCGCGGGCGCCAAGTTCGTTCCCGCCTCGCCCGGTTGGGGCCGGATCGACTCCTCGCTGGTGCTGCCCACGATGTTCCAGGAGATCGTCAGCGGAAAGAAGGACGTGGCGAAGGCGTCATCGGACGCGGCGAAGAGGATGAACGACGTGTTCGGGGCGGCGGGTTGAGCCCGGCGACCGCCGAGCGCGCGACGGCCCCGGCGCCCCCGACCGGGCTCGCGCCGGGGCGCGCACGCGGCCGCCCGGTGCGCCGGGCCGGCTGGACCCCGTGGCTGTATCTGGCCCCCGCCCTCGCCGTCCTCGGCGCGCTCCTGGTCTACCCGATCTACCAACTCGGCCTGATCTCCTTCCTGGAGTACACCCAGGCCCAGGTCAGCGGCGGTGAGCCGACCAGCTTCCAGGGGTTCGGCAACTACGCCGAGCTGTTCTCGGACAGCCAGTTCTGGTCGGTGCTGCTCGCCACCCTCGTCTTCGCGGCGGCCTGCGTCCTGAGCACCCTCGCGGTCGGCTGCGCGCTGGCCGTCCTCCTCACGCGGGTACGCGCACTGCCCCGGCTCACCCTGATGCTGGCCGCGCTCGGCGCGTGGGCGACGCCCGCGATCACCGGCTCGACCGTGTGGCTGTTCCTCTTCGACCCCGACTTCGGCCCGGTCAACCGGGTCCTCGGCCTCGGCGACCACTCGTGGACGTACGGCCGCTACAGCGCGTTCCTGCTCGTCCTGCTCGAAGTGGTGTGGTGCTCCTTCCCGTTCGTGATGGTCACGGTGTACGCCGGGATCCGCGCCATCCCCGGCGAGGTCCTGGAGGCGGCCGCCCTCGACGGGGCCTCGCAGTGGCGGATCTGGCGGTCCGTCATGGTGCCGATGCTGCGCCCGATCCTCACCGTCGTCACGATCCAGTCCGTCATCTGGGACTTCAAGGTGTTCACCCAGATCTACGTCATGACCAACGGGGGCGGCATCGCCGGACAGAACCTGGTCCTCAACGTGTACGCGTACCAGAAGGCGTTCGCCTCGTCGCAGTACAGCCTCGGCTCGGCGATCGGCGTGGTGATGCTGCTGATCCTGCTCGCGGCGACGCTGGTGTATCTGCGGCTGCTGCGCCGCCAGGGGGAGGAACTGTGAGGTCCCTGACCGCCCTTTTCGCGGTACGGATCCGCAGGCCCGGGCGGCTGATCGCCGAGGGGGCCGCGCTCCTGGTGGCCGCGGTGGTGGCCTTCCCGCTGTACTGGATGGCCCTGTCCGCGTTCAAACCGGCGGGGGAGGTGCAGTCCAGCCACCCCAGGCCCTGGACCCTCGCGCCCTCCCTCGACTCCTTCCGCCGGGTCTTCTCGCAACAGGACTTCGGGCGGTACTTCCTCAACAGCCTGATCGTGGCCGGGTCCGTGGTGCTGCTCTCGGCGCTGATCGCCTTCCTCGCGGCCACCGCGGTGACCCGCTTCCGCTTCCGGTTCCGCACCACGCTGCTGATCATGTTCCTGGTGGCGCAGATGGTGCCGGTCGAGGCGCTGACGATCCCGCTCTTCTTCCTCATGCGGGACCTGGGGCAGCTCAACACGCTGGGCTCGCTGATCCTGCCGCACCTCGCGTTCTCGCTGCCCTTCGCGATCTGGATGCTGCGGGGGTTCGTGAAGGGGGTGCCGGTCGCGCTCGAGGAGGCGGCGGCGCTCGACGGTGCGAGCCGCACGCGCTTCCTGTGGCAGATCCTGTTCCCGCTGGTCTTCCCCGGGCTCGTGGCGACCAGCGTCTTCTCCTTCATCTCCGCGTGGAACGACTTCCTCTTCGCGAGGTCGTTCATCATCAGCGACACCTCGCAGTCCACGTTGCCGATGGCGCTGCTTGTCTTCTTCAAGCCGGACGAGAACGACTGGGGCGGGATCATGGCGGCGTCCACGGTCATGACCGTGCCGGTGCTGGTGTTCTTCGTGCTGGTCCAGCGGAGGCTGGTGAGCGGGTTTGGGGGCGCCCTCAAATAACCCCCTGGGCTCCGCCCCGGCCGGGGGGGTTGCCCACCCACCCACCCGTGCGGCGGGTTGGAGGGTTCGGCCCCCTGGGGCCCGCGGGTTCGCCCACCCCCCACCCGTGCAGCGCGTTGAACGGGCTGACCCCCTGGGGCTCCGCCCCAGACCCCGGGGGTCTGCCCACCCACCCGCCCGTGCAGCGGGTTGGTTGGTTCCGGGCCCCTGGGGCTCCGCCCCAGACCCCGGCGGGTTCGCCCGCCCACCCGCCCGTGTAGCGGGTTGGATGGTTCGGCCCCTGGGGCTGCGCCCCAGACCCCTGCGGGGGCTCTGCCCCCTGCACCCCCGTTCGCGCCTGAACGGCGCTCGTCCTCAATCGCCGGACAGGCTGTAGGTGCCCCCGCACCGAGCACTTAAGGGGCGCGAGGAACTGCGCGACCAGCCACGCACGGTGCGAGGACGAAAGGGGGGTCTAGGGGCGCGGGGAACTGCGCGACAAGCACCCCGGTCCACTCAGCCCCAACACCCTCCGCCCCCAACACCCCCCTCACCCACACCCCACCCCCACCCCCCCGAGAGGACCCCGATGGACATCGACCACCTCATCCCCGCCCCCACCCGCACCCACCCCACCCACCCCACCCCCACCCACCTCACCCCCACCACCACCCTCCACACCACCCCCGAAACCTCCCCCCTCGCCCCCCTCTTGAGGGGAACCATCGGGGTCGCGACAGGGCTCCCCCTCGCGGACGGCGGTGTCGGGGCCGAGCGGGTCGTGTTGCGGGTCAGGGCGGAGATCGGCGGGCGGCACGGCCCCGAGGCGTACCGGCTCTCCACCGACCGCTCCCACGAGGACGCCACCGTGCTCATCGAGGGCGGCACCCCCGCAGGCGTCTTCCGCGGGATCCAGACCCTGCGGCAGCTACTCGGCCCCGACGCCTTCCGCAGGGCTCCCGTCGAGCCGGGCCGCCGCCGGCGGCGCTGGGCGCTGCCGCAGGTCACCGTCGAGGACCACCCCCGCTTCGCCTGGCGCGGCCTCATGCTCGACGTGGCGCGGCACTTCATGCCGAAGGACGGCGTGCTGCGCTACCTCGACCTCATCGCCGCCCACAAGCTCAACGTCTTCCACTTCCACCTCACCGACGACCAGGGGTGGCGGATCGAGATCAAGCGCTACCCACGGCTCACCGAGGTCGGCGCGTGGCGCGGGCGGACCAAGTGGGGGCACCGCGCCTCGCCCCTGTGGGACGAGAAACCGCACGGCGGGTACTACACCCAGGACGACATCCGCGAGATCGTCGCCTACGCCGCCGAGCGCCATATTCGCGTCGTTCCCGAGATCGACCTCCCGGGACACTCGCAGGCCGCCATCGCCGCGTACCCTGAACTCGGCAACACCGACGTCATCGACACCGCCTCCCTCTCCGTCTGGGACACCTGGGGCGTCAATCCGAACGTACTCGCCCCCACCGACACCACCCTCCGCTTCTACGAAGGGGTGTTGGAGGAGGTGCTCGACCTCTTCCCCGAGGACGTCTCGCCCTTCATCCACATCGGCGGCGACGAGTGCCCCAAGGAGCAGTGGCAGAAGTCGGACGTCGCGCAGGAGCGGATCCGCGAACTCGGGCTCGCCGGTGAGAACGAGCTCCAGTCCTGGGTCATCCGGCACTTCGACACCTGGCTCAGCGCCCGTGGACGCCGACTCATCGGCTGGGACGAGATCCTGGAGGGCGGGCTCGCACCCGGCGCCGCCGTCTCGTCCTGGCGCGGATACGGCGCGGGGATCGCCGCCGCCGAGGCCGGGCACGACGTCGTGATGTGCCCCGAGCAGTACGTGTACCTCGACCACCGGCAGGCCGCGGGCGCCGACGAGCCCGTGCCCATCGGGTTCGTCCGCACCCTGGAGGACGTCTATCGCTTCGAGCCCGTTCCGCCTCAGCTCGATCCCGAGGCCGCCGCCCACATCCTGGGCACTCAGGCCAATGTCTGGACCGAGGTGATGGAGAACCAGTCCCGCGTCGACTACCAGGTGTTCCCCCGTCTCGCCGCCTTCGCCGAGGTCGCCTGGAGCGCACTGCCCGCCCCCGCCGACCGGGACTTCGCCGACTTCGAGCGCCGAATGACCGTCCACTACAAGCGCCTTGACGCGCTCGGCGTCGACTACCGCCCGCCCACCGGGCCGTTGCCCTGGCAGCAGCGCCCCAGCGTGCTCGGACGCCCGATCGAGGGGGCGCCCCCAAACAGGTGAGCCCCGCCCCAACGCGGCGCCCCACCGCCGCGCCCCTGAGAACGTGGCCCCGGGTCACGGCCGCCCCGGCCGCGCCCGGCTGCGAGGAAGACCGCTGTGACGAACTCCCGGGGTGCGGAACGAGGCGTACCGCATAAGTCGTACAAGGCTTGCGAAACCGGAACATTCCCCTGGTCGGGGACGGAAGCGCGCTTCGTGGACCCTCCCGTCGCGCGGTCCGGAAGATGTGCCAGAGTTGCCACGTCCGGGCTGTGAGCACGTACGGTACGGCCATCAGCAGGTGGCCACAGACGGCACAGTCGTACGGCCGGGACACCGGGAAGGGGCAGCTGGGTTGACCACGCACGCACCGCAGGCGGCGCAGTCGGTGACGCTGCCTGCCTCACTGGACGAGGCCGTGGCGGCGCTCGCGGCCATGCCTGCCGCCGTGCCCGTCGCGGGCGGCACCGATCTGATGGCGGCCGTGAACCGGGGCCTGCTGCGCCCCGCCGGCCTCGTCGGGCTCGGCCGGATCAACGAAATCCGCGGCTGGCAGTACCAGGACGGCCACGCCCTGCTCGGTGCCGGTCTCACCCACGCCCGGATGGGGCGCCCGGACTTCGCGGCGCTCATCCCGGCGCTCGCCGCCGCCGCGCGCGCCGCCGGGCCCCCGCAGATCCGCAACGCGGGCACCCTCGGCGGCAACATCGCCTCCAACGCCCCGACCGGTGACGCGCTGCCCGTACTCGCCGCGCTCGAAGCCACCCTGGTCATCGCGGGTCCGGACGCCGCCCGGCGCGAGATCCCCGTATCGCACCTGCTGGCCGGCCGGGACATGCTCGCCCCGGCCGAGTTGATCGGTTATGTCCGGGTGCCGCTGTTGCACGCCCCCCAAGTTTTCCTCAAGGCGACCGGCCGCACCGGTCCCGGCCGGGCCACCGCCTCGGTCGCCGTCGTCCTCGACCCGGCCCGGCGCGGAGTGCGCTGCGCGGTCGGCGCCATCGCGCCCATGCCGCTGCGCCCCCTGGAGGCCGAGCGCTGGATCGCCTCGCTCATCGACTGGGACGGCGAGCGCGCCGCGCTGGCCCCCGAGGCGCTCGGCGCGTTCGGCGAGTACGTGGCCGCCGCCTGCATCCCGGACCCGGCGCCACCCGCGGACGGCTCACCGCCCCCGCCGCTCTCGCCCGCCGTACTGCATCTGCGGCGCACCGTCGCCGCGTTGGCCCGACGAGCACTGGGGAGGGCGCTGTCGTGACCGACCGGAACAATGAGCACGAGCCCGAGCGCGGACACGAGAACGACTACGGCCGCGGACGCGAGAACGAGTACGAGTACGGGTACGGGCGCGGGCCCGAGAGCGAGAACGAGAACGAGTACGGGCAACCGCACCAGTACGGCTACGGCCAGGCGCCCCGGCACGGTGCCTGGGAGCCGGTGCCGCACGGCGGCGAGTACGAGCCCGACGCCACCGCGTTCGTCCAGCTGCCCCCGGACATGGACATGATGGGCGCCCCCCTCGCGGCGCCCGGCCACGGCTACGTACCGCCGATGATCGTGCCGCTCACCCCGCTCGCTGCGACGGACCCGGGGGCCACCGGCATCTGGCGCATCCCGACCGAACCGGCCGAGCCCGCCGAGTCGAGCGAGCCAGGCGACCAGGGCGCGCCCGGCGCGTCCGGGGCCCACCCCGCGCCCGGCGCGCAGACCGTGGTGTGGCCGGAGCCCCCCGCGCCCACGCCCCTGCCCGCGAGCTCCGCCCAGCCCGCCCACGACCCCTCCGCCACGGCCCAGTGGCACTTCCCCGACGAGCCTTCGCTCGCGGGCACCGGCCAGTGGACGATCCCGGTCGCCGAGGGTGAACTCCCGGAAGAATCGGGCGAGTTCACGACCTCCGCGCTGATCGAGCAGTGGGGTTCGACCCCGCCCGCCACCCTCCCCGGCGGCGCCCCCGCCCCCTGGGCCCACCAGTTCCCGGAGCCCCCGCAGGAGCCCCTGCCGGACCCCGCGCAGGAGCCGCTGCCGGTCCCCTCGCCCGAGGCCCATGCGCCCACGCCGGGGCACGCGCCCCTCGCGGCCGACCACCCCGCGAACGCCCTGGACGTGCACCACGACGTCCGCCCTGACGTGCACCACGACGTCCACCCTCACGAGGCCCCGGACGCCCCGCTCGCCCCGGACGCCTCAGAAGTCCCCGTACTCCCGGGAGCGCTGGAGGCGCCCTCGGCGGCGCACGCGCCGGTGGTACCGGACGTCCATGACGTGGCGGAGGCAGGCGCGATGCCCGCCCCCGCCTCCGTACCCGAGTCCCGGCCCCACCCCCAGCCCCACCCCGCGTCGGAACCGCGGCCCGAGTCCCCGGCGGCGCCGACTGCGCCGGAGTCGCTCCCCGAGGAGCTCGTCGCCGTCGAGCCCCTGGCCGAAGCCGTACCGGAATCCCACGGTATGTCCGAGGCGGCCGTATTGGCCGAGTTGGCCGAGTTGGCCGGGGCACCCGAGGCGGAGCTCGCGCCCGGAACAGGAACCGGAACCGGGGCCGAAACCGCGGCCCTCCCCGGGACCCCCGAGCCCACCGACGCCCCCGACGCGACCGGCACCACCGACACCCCCGCGCCCTCCGGGGCATCAGGAACCGACCGCGGGACCGACCTCGCAATCGACCTCGGGACCGACCCCGGCGACGCCACCCCCGATGCCGAGCCGACCCCCGCCGTCACCATCGCGCCGGACCTCGAACACCCCCGCGCCTCCTACGTGTTGCGGGTCAACGGCGCCGACCGCCCCGTGACCGAGGCCTGGGTGGGGGAGTCGCTGCTGTACGTGCTGCGCGAGCGGCTCGGGCTCGCCGGGGCCAAGGACGGCTGTTCGCAGGGCGAGTGCGGGGCGTGCAACGTCCAGGTGGACGGGCGGCTCGTCGCCTCCTGCCTGGTGCCCGCGGCGACCGCCGCCGGCAGTGAGGTGCGTACCGTCGAGGGGCTCGCCACCGACGGCGAACCCTCCGACGTGCAGCGCGCGCTGGCCGAGTGCGGCGCCGTCCAGTGCGGCTTCTGCATCCCCGGCATGGCCATGACCGTGCACGACCTCCTCGAGGGCAACCACGCCCCCACCGAGCTCGAAACGCGCCAGGCGCTCTGCGGCAACCTGTGCCGCTGCTCCGGCTACCGCGGCGTGCTCGACGCCGTGAAGGACGTGGTGGCGGGCCGCGAGGCCGCCGGTGCCCTGGCCGAAGAGGCCCGCATTCCGCACCAGGCACCCCCCGGGGCCGGCAGCGCCATGCCCCCGCACACGCACGACGGAGGCATGGCGTGAGCAACGACGCAGCCACCGCGACGGTCGAAGGCGCCACCTCGGTGGCGGGGCCGGAGCAGCAGCCGCCCGCACACGGGATCGGCGCGTCGCTCGCGCCGGTCGACGCGCGGGCGAAGACGGAGGGGACCTTCCCCTACGCGGCCGACCTGTGGGCCGAGGGCCTGCTGTGGGCGGCCGTGCTGCGCGCCCCGCACGCGTACGCCCGGATCGTCTCGATCGACACCGCGGCCGCCGCCGCCATGCCGGGCGTACGGGCCGTGGTGACCCACGCCGACGTGCCGGGCGACCCGGCGTTCGGCCGCCGCATCGCCGACCGTCCCGTCTTCGCGGCCGAGTACGTACGCCACCACGGCGAGCCCATCGCCGCCGTGGCCGCCGACCACCCGGACACCGCGCGCCTGGCGGCCGCGGCGATCGCCGTTGAGTACGAGGTGCTCGAACCGGTCACCGACCCGGAGAAGGCGTTCACGGCCGAACCCCTGCACCCCGACGGCAACTTGATCCGCCACATCCCGCTCCAGTACGGCGACCCCGAGGTCACCGGCGACGTGGTGGTCGAGGGTCTGTACCGGATCGGCCGCCAGGACCCGGCCCCGATCGGCGCCGAGGCCGGCCTCGCCGTGCCGCGCCCCGACGGCGGCGTGGAGCTGTACACCGCCTCCACCGACCCGCACGGCGACCGCGACGCGGCGGCCGTCTGCTTCGGTCTGGAGCCGGATCGCGTCAAGGTCGTCGTCACCGGGGTGCCCGGCGCGACCGGTGACCGCGAGGACCTCGGCTTCCAACTCCCGCTCGGCCTGCTGGCGTTGAAGACGGGCTGCCCGGTCAAGCTGACCGCGACCCGCGAGGAGTCCTTCCTCGGCCACGCCCACCGCCACCCCACCCTGCTGCGCTACCGCCACCACGCGGACGCCGAGGGCCGCCTGGTCAAGGTCGAGGCGCAGATCCTCCTCGACGCGGGCGCCTACGCCGAGGCGTCCGCCGAATCCCTGGCCGCCGCCGTCGCGTTCGCCTGCGGGCCCTATGTCGTGCCGCACGCCTTTGTCGAGGGCTGGGCGGTGCGCACCAACAACCCGCCGTCCGGCCATGTCCGGGGCGAGGGCGCGATGCAGGTGTGCGCGGCCTACGAGGGCCAAATGGACAAGCTGGCCGCCAAGTTGGGCATCGATCCGGCCGAGCTGCGGATGCGCAACGTGCTCGCCACCGGCGACCTGCTGCCCACCGGCCAGACGGTGACCTGCCCGGCGCCGGTCGCCGAACTCCTGGGCGCGGTACGGGACTTCCCGCTCCCGACCCTCCCCAAGGACGCCCCCGAGGACGACTGGCTGCTGCCGGGCGGGCCCGAGGGCGCGGGCGAGCCGGACGCGGTGCGGCGCGGTGTCGGCTACGCGCTCGGCATGGTGCACATGCTCGGCGCGGAGGGCACCGACGAGGTCTCCACGGCCACGGTCAAGGTCCACGACGGCGTCGCCACGGTCATCTGCGCGGCCGTCGAGACCGGCCAGGGCTTCACCACGCTCGCCCGCCAGATCGTCCAGGAGACCCTGGGCATCGAAGAGGTGCACGTCGCGCCGGTCGACACCGACCAGCCCCCGGCGGGCCCCGCCACCCACGGCCGGCACACCTGGGTCTCCGGCGGCGCGGTGGAACGCGCGGCCAAGATGGTCCGCACCCAGCTGCTCCAGCCGCTTGCGCACAAGTTCGGCATGTCCACGGAGCTGCTCCAGATCGCGGACGGCAAGATCACCTCGTACGACGGCGTCCTGTCGACCACGGTCACCGAGGCGATGGACGGCAAGGAGCTGTGGGCCACCGCCCAGTGCCGCCCGCACCCCACCGAGCCGCTCGACGAGACCGGCCAGGGCGACGCGTTCGTGGGCCTCGCGTTCTGCGCGATCCGCGCCGTCGTGGACGTCGACATCGAGCTGGGCTCCGTCCGGGTCGTCGAACTCGCGGTGGCCCAGGACGTCGGCCGGATCCTCAACCCCCGCCAGTTGACGGCCCGTATCGAGGCCGGAGTGACCCAGGGCGTGGGCGCGGCCCTGACCGAGAACCTCCGTACGGTACGCGGCCGGATCCGCCACCCCGACCTCACCGGCTACGCGCTGCCGACCGCCTTGGACGCCCCCGACATCCGCATCGTGAAGCTGGTCGAGGAGCGGGACGTGGTGGCCCCCTTCGGCGCGAAGGCGGCCAGCGCCGTCCCGGTCGTGACCTGCCCGGCCGCGATCGCCTCCGCGGTCCGCGCCGCGACCGGCCGACCGGTCAACCGCCTCCCGATCCGGCCCCAGGCGGCGGTGGTCCAGCAGGGCTAGGCGCGCGCGGTTTCCCCCGGCCAGGCCCGCTCCCGTGCGGCCGGGCCCGCTCCCGTCCGGGCGCGCGCCGTTCCCTCGGCGGGGTGACGCCGGGGATGCGAGCGCCTCCGCCCCGCCCCGTCCATCGTTCCCGACCACCCCTCGACGCCATACCGTGACGGTCCGCGTACCGTACGCTGCTGGCGCAGGGACGGTAACCGACGTGCGGGGTACGGGAGTTGGGCATGGCGTCAGGGGCGGCAGCAGGAACGCAGGGGACCCGTGGGGTCGAGGGGGCGCCGGGGGCGGACGGTGGCGATCTCGTCGCCCACGCCGACGACCTCGGGCTGATCGGCTCGGACGCGTACAAGCTGTACGACGGCTTCCGTCGCGACGGCGACCACGCGAGGGCGGCCACCTTCGAGGCGGCGCGCGCCCTGAGCGCGGACAACTTCACCAGCGGCGCCGCCCTGATGAGGCTCCACGACACCTGGCAGAGCCAGTACACGACGCTCCGCGACGCCTGCGCGCAGATCTCCAACCACCTCGACCACTCGACCGCCCAGCACGCGAAGGACGACGCGCGCGTGCGGGGCTCGCTGACCGCGGTGTCCGTACTCAGTGACTACATCAACTAGCGGGCGGAGCAGGGACGTTGTTGACGTACGCCGATGTGTTGAACGCTCCGGTCGGCAAGCTCGGGGCGGCGGTCGACGCCTGGTCGGAGATGACGGCCAAGCTGAGGGAGCTCTCCGAAGAGGCCCACGACGGCCTGCGGGTGCACGCCGAGACGGCCAGATGGGCCGGGGTGAACGCCGGGGTCACCCGCGCGTTCATCGTCAAGACGGTGAAGGAGTTCGCGGACGCGGAGAAGGAGGCCGAAGGGGCGCACCGCCTTCTCCTGGACGCGTACACGGAGTTCAAGAAGGCGAAGGACGGGCTCCAGGCGATCGTGGACGGCGCTCGGGGCAACGGCATCGTCGTCGACGCGCGGGGCCGGGTCGCGGCCCGCGAGCCGCTCGTCGACGACGCGGCGGCGCGGCACGACCCCGACGTCGACTTCCCGAAGGCGCTCAAGACGCAGGAGGCGAACGTCGCCGCCTGGCAGCACAAGGTCGACGCGCTCGTCGCTGCCTGCGACGCCGCCGACCAGGCACTGCGCGGGGCCCTCGCGGCGAACGCCCCCGACGCGCACGACTTCACCGCGCCCCGGTACGCCTCCCTCGACGACGAGGAAGCCGGGCGGGCGGTCGACCTGGCGCGACAGGTCACCGGCGAGGGCGGCACGGCACGCAACGTGGAGGAGCTGAAGCAGCTCCAGACCCTGCTGGACGCCAACGCCCACGACCCGGAGTTCTCCACCGCGTTCTACGGCCGTCTCGGCCCGCAGGGCACCCTGGACTTCTACGCCCGCCTCTCCCTCGACGCGACCGGCCTCGGCGCCGCGGGCCTGGACCGCGCGACGATGGTCCGCCACGTCCAGGCCGACCTGGGCCCGATGCTGGGCCTCGCCACCAACCCGCACACCACCGGCCACCTCCCGCCCGCCTGGACGACCGACCTGATGCGGGCGGGCCGCCGGCCCATCGACGTCGGGGGTTTCGCGGGTCCCGGCGCGCGGGTGTACGGCTACCAGGCGCTGGGCGCGCTGCTGCGGCACGGCACGTACGACAAGGAGTTCCTGCTGCCGATCGCCCGCGACATGGTCGGCTTCGAACACCAGAACCCGAAGCTCTTCCAGCAGAGCGTGCCGTACGACAACGCGATGTCCCTCAACCTCGACAAGACCGGCGGTCGCGGCTTCGACCCCCTGACCGGCCTCATGACGTCCATGAGCAACAACCCGCGGGTGTCGGCGGAGTTCTTCAACGAGGCGGTGCGGGAGGACTCGGACGGCAACGGCATCATCACCGCGGACGACAAGCCGGTGCTGACGAAGGCGGCGGGCGACGCCTCATCCGCGCCGCTCGGCATGGTCGACTACCTGCTGGACAAGGGCCCGGGCGACGACCTGTACGACGCCCGCCCCGACGCCCGCACCCCGTACCAGTCCGCCCTGGGCAACGCGATCGAGGCGGCCACGACGGGCCGCACCCCCGGCGACACGGCGGCGAAGCCGGTGGAGCATACGGCGGCGATGGCGAGCGTGATGGAGAAGGTCGTGGCGAAGATCGGATCCGACCCCGCCCTGGTCACAGGTGAAGACGGCGCACCGGGGAAGTTGGAGGGGCTTTCGGGCAACTTGGGAAACATGGCGGCGGAGTACATGCCCGACTTGCAGGCGACGGCGGAAAACGGCGCGGGGCAGGCGAAGCCTTTCGGGGTGCTGGCGGACTTCGTCAACTCCGGGCGAGTCGCGCATTTCCTCGGCGCCGTCGCACAGGATCCCGATGCGTACGGCGCGATCACCAACGCTCAGCAGGCCTATACGACATTGCTCGTACGCGATGTCTTCGCGTACCCGGAAAACCATGGGGATGTGGGGGAAGCCGTGCGCAACGCGGTTCACCCGGGTGGGGAGATCGCGGGAATGATGGCTGAGGCTCGTGTGCAGGCCATCTATGAGAAGCACGCGGAAACCGACAAGACCTTCAACGATGCCGTGCAGAACAAGGCGGACTGGACGAACCGAATCCTCAACTCGGTCGGCGCCAAATACATCGAGCTGCTGCCGGTCGGCGGTGACGCCGTGGAATGGCTCCAAGAAGACATCACCGAGTCCCTTGTCGAGAACAGGCAGAAGGACTCGTCCGGCGAGGCGAGCCAAGAGGCGGCCGACGCTTACGCGGCGGCCGAGGGCAAGGCGAAGAAGTCGGCGGCAGGCGCGGTGAGGGCGGCCGGCAACAGCGTCGGCCTCGCCGAACGGGAAAACCGCGAATACCAGGGGGTCGCGTCCTCTTCGATCTCCGTCGCCTATTCGGCGGGCCGCTCGGCGGTGGCCAGCGCCACGCCTCCCGGTGGCGCGAAGTGAGGCGTGGTCGAGGGGCGGGCTTCGTGTCTGTGCTTACGGCGGTGTGGGCCATGGCGGGCTGCTCGGCCGACTCACCGGTGCCGAGCCTGCCGAAGAGCTTGTGCTGGGGAGCCTTCGCGGGCAGCGCGGTTGCCCCGATAGTGCCTACGGGTGACGCCACGACCGTGGAAAACAATCGCCCCTTCGACGTCTTTGCTCCCACGGACCAAACCACGTACTGCACGGTGCGCGTCGACAACGACGCACGGTTCATAGCCTGGGCCGAACTCCGGAGGAGTGGAAAAGGCACGGATTGGAACCACTCGGCACGCCATTTGGGTACACGCATCGAGGCGGGTGACGAGGCGTTCGTCTGGGGCGGAGACGCCGCCGCCGTATTCGAGTGCGGCCGCCCGGACGTTGCCAGGGGGCCGACGTTGCCGGCCTCGGCCAAGTACATCGAGCTGCAACTGACGGCGGACCGGGCGCCTGAGACGCAGCGGACCCGGGACGTGCTCACCACCCTGATGCGGCAGTACGTCCACTTCGCGAAGCAAAGACTCAAGTGCCGCTAGCGAAAAAGGGCTTGGAGGCCGTGGCGGGAATCGAACCCGCGTAACTCGCTTTGCAGGCGAGTCCCTGAACCACTCGGGCACACGGCCGTGTCGGTTGGTGCGTACTGATGACTTTAGGGGGGTGTCCGGGGCGGGGGAAGGGAAAGGGGCGGGGTGCAATAGGACTGCCATGTTGTGTTCACGGGGGTTCATCGGGCGTCACACCCATGTCATACGACGGGGACGATCGGCGCGGCGCAGTCGGCCTTTCGGCAGGGGGCGGAGCGGGGTGTGGCTCTTAATGTGGGCGGATGAGCGCCCTTGAACCGTCCGATGTCCGCGTGGCCGGCCACCCCTGCGCCGAGGGCGACGAGGGCGGCGGCATCCTGGGGCGTGAGCATCGCGCGCTGAGCATGGGCATTGTCACCGTCGTGCTGCTCATCGCCTTCGAGGCGACCGCCGTGGCCACCGCGATGCCCGTCGCCGCGCGGGACCTCGACGGGGTGTCGCTGTACGCCTTCGCCTTCTCCGCGTACTTCACGACGAGCCTGTTCGGGATGGTCGTCGCGGGCCAGTGGGCCGACCGGCGCGGGCCGCTCGGGCCGCTCGGCGTCGGGATCAGCGGGTTCGCCGCGGGGCTGCTGTGGTCGGGGACCGCGCTGAACATGTGGACGTTCATCGCGGGCCGCGCCGTACAGGGGCTCGGCGGTGGTCTGGTGATCGTGGCCCTGTACGTGGTCATGGGCCGCGCCTACCCCGCCCGCCTCCAGCCGACGATGATGGCGGCGTTCGCGGCGGGCTGGGTCGTGCCGTCCGTGGTCGGCCCGCTCGTCGCGGGCGCGGTCACCGAACAGCTCGGCTGGCGCTGGGTGTTCCTCGGGATCCCGGCCCTCGTGGTGTTCCCGCTGGCGCTCGCGCTGCCCGCGACGCGGCGGATGGCGTCCGGCCCGGCCGATCCGTCCGCGCCCGTCGAGCCCTTCGACCGCCGCCGCATCGGCCTTGCGCTGGCGATCTCGGTGGGCGCGGGGCTCTTGCAGTACGCCGGGCAGGACCTCGGATGGCTCTCCGTGCTGCCCTTCGCGGCGGGCGTGGCCTTCCTCGGGCCGGCCGTCGCGGGCCGGCGCGCGCTCCTTCCGCACGGCACCTGGCGCGCGGCGCGCGGGCTGCCTTCCGTGGTGCTGCTGCGCGGGATCACGGCGGGGTCGTTCGTCGTGGCGGAGTCGTTCGTGCCGCTGATGCTCGTCACCCAGCGCGGGCTCACCCCCACGATGGCCGGACTCTCGCTGGCCGTCGGCGGGGTCACCTGGGCGGTGGGTTCCTCCGTCCAGGCGCGGCCCCGCATGGAGGCGTACCGGGAACGGATGATGGTCGTCGGCATGGTCCTGGTGGCGCTCGCGATCGTGTTCGCGCCGAGCGTGCTGGTCGCGGCGGTGCCGGTGTGGGTGGTGGCGGTGGCGTGGGGCGTCGGCTGTTTCGGCATGGGCATGGTCATCACCTCGACGAGCGTGCTGCTCCTGAAGCTCTCGGCGCCCCACGAGGCGGGCGCGAACTCCGCCGCGCTCCAGATCTCGGACGGGCTGTCCAACGCGCTGCTGCTGGCGGCGGGAGGCGCGGCGTTCGCGGCGCTCGGAGGTGGCTCGGTGTCGGGTCCGACGGGTTCGCACCCGGGTGCCTTCCTGGCGGTGTTCCTGCCGATGGCGGGGGTGGCGCTGTGTGGGACGTGGGTGGCGGGGCGGGTACGGGTGGGCTGACGCCCGGTTTGGCGGTGTTGACGCCCGCCCCTGCCGCGCCGGGGTCGGCCTCGCCGGGTCCGAACCCGCTCGGTCCTGCGGGCCGGGGTGCTGGTTGCGCAGTTCCCCGCGCCCCTATACCCGCTCGAAGCTGCGGACCGTGCCCGCTTCTCGCGCAGTTCCTCGCGCCCCCAAAACCCGCTCGAACCTGCGGACCGCGGTCGCTTCTCGCGCAGTTCCTCGCGCCCCCAAAACCCGCTCGAACCTGCGGACCGCGGTCGCTTCTCGCGCAGTTCCTCGCGCCCCCAAAACCCGCTCGAACCTGCGGACCGCGGTCGCTTCTCGCGCAGTTCCTCGCGCCCCCAAAACCCGCTCGAACCTGCGGACCGCGGTCGCTTCTCGCGCAGTTCCTCGCGCCCCCAAAAACCCGTTTTCGGCTGCGGGCCTTGCGTGGCTGGTCGCGCAGTTCCTCGCGCCCCTTAACTGCTCGGTGCTGGGGCACCTTCAGCCTGTCCGGCGATTGAGGACGAGCGCCGTTCAGGCGCGAACGGGGTCTGGGGCGGAGCCCCAGGGGGCCGGAACCAACCAACCCCCGGCACGGGCGGGTGGGTGGGGAGACGCCTCGGGGCCGGCCCGGGCCGGTAAGGTGGCCCGGTTGTCGTACGTACGAGTCGGTTCCGCGCCCGCCCGGGCAGACGCGGACCCCGCTCGGCAGCCCGCCGGGCCCCGCCCCGGATGCCCGTGATCCCGTACACCGAGAGCCCCGAACCGGAGACCGTGACTACTACCGCCTCCCACCACCTCTCACCCGCCTTCCCCGGCCGCGCCCCCTGGGGCACCGCCAACAAGCTGAGAGCCTGGCAGCAGGGTGCCCTGGAGAGGTATGTCCAGGAGCAGCCGCGCGACTTCCTCGCCGTCGCGACGCCCGGCGCCGGCAAGACGACCTTCGCGCTCACGCTCGCGTCGTGGCTGCTGCACCACCACGTGGTGCAGCAGATCACCGTGGTCGCGCCGACCGAGCACCTCAAGAAGCAGTGGGCGGACGCCGCGGCCCGGGTCGGCATCAAGCTCGACCCGGACTACAGCGCCGGGCCGCTCAGCAGGGAGTACCACGGCGTCGCCGTCACCTACGCCGGTGTGGGCGTACGCCCGATGCTGCACCGCAACCGGTGCGAGCAGCGCAAGACCCTGGTCATTCTCGACGAGATCCACCACGCCGGTGACTCCAAGTCGTGGGGCGAGGCCTGCCTGGAGGCGTTCGACCCGGCCACCCGGCGGCTCGCGCTCACCGGCACCCCGTTCCGGTCGGACACCAACCCCATCCCCTTCGTCACGTACGAGGAGGGCAACGACGGCATCCGGCGCTCCTCCGCCGACTACACCTACGGATACGGCAACGCCCTCGCCGACGGTGTCGTGCGGCCGGTCATATTCATGAGCTACAGCGGCAACATGCGCTGGCGCACCAAGGCCGGCGACGAGATCGCGGCGCGGCTCGGCGAGCCCATGACCAAGGACGCCATCTCGCAGGCCTGGCGCACCGCGCTCGACCCGCGCGGCGACTGGATGCCCAATGTGCTGCGCGCCGCCGACCAGCGCCTGACCGAGGTCAGGAAGGCCATCCCGGACGCCGGCGCGCTCGTCATCGCCTCCGACCAGGACTCCGCCCGCGCCTACGCCAAACTGATCCGCGAGATCACCGGCTCCAAGGCGACCGTCGTGCTGTCCGACGACACCGGCGCCTCCAAGCGGATCGACGAGTTCGCCGAGGGCGACGACCGGTGGATGGTCGCCGTGCGCATGGTGTCGGAGGGCGTCGACGTGCCGCGCCTCGCCGTCGGGGTGTACGCCACCACCATTTCCACCCCGCTGTTCTTCGCCCAGGCCGTCGGCCGCTTCGTGCGTTCACGGCGGCGCGGCGAGACCGCTTCCGTTTTCCTGCCCACCATTCCGATGCTCCTCGGCTTCGCCAACGAGATGGAGGTCGAGCGCGACCACGTGCTCGACAAGCCGAAGAAGGACGGCGAGGAAGAAGACCCCTACGCCGAGTCCGAACAGGAAATGGACGAGGCGAACAGGGAGCAGGACGAGGACACCGGGGACGACATGCTCCCCTTCGAGGCCCTCGAATCCGACGCCGTTTTCGACCGGGTCATGTACAACGGCGCCGAATTCGGCATGCAGGCCCACCCGGGGAGCGAGGAGGAGCAGGACTATCTCGGCATTCCCGGGCTCCTCGAACCCGACCAGGTGCAGATGCTGCTCCAGAAGCGGCAGGCCCGGCAGATCGCGCACAGCCGCCAGAAGCCGGCCGAGCAGGCCGATCTCCTCGAAATGCCGGCCGAGCGGCGCCCCGTCGTCTCGCACAAGGAACTGCTCGAACTGCGCAAGTCGCTCAACACGATGGTCGGCGCCTACGTCCACCAGAGCGGCAAGCCGCACGGCGTCATCCACACCGAGCTGCGCCGGGTGTGCGGCGGTCCGCCGAGCGCGGAGGCCACGGCGGGACAGCTCCGCGAGCGGATCAAGAAGGTCCAGGAGTGGGCGACCCGCATGAAGTAGCGGGCCCCCCACGGCGTACAAGGCGAAGGGGTCCGGCGTGCGACGCCGGGCCCCGTTCGCTCCCGGGGCATCGGGACGGGTGCGAGGAGCGGCCCCCACGGACGCCCCCGACCGTCCGCCACGGTAATGACCCGGCAAATCCATCACGGTCGCCCGAGGTCGCCGCTCGGAAGGACTTAGGTCCCGAAGGGGATCGAACGGGATCAAATTCATCCCCCACGGGTCATCATTTGTCCATCTGCCGGGGATGCTCAGCCCATTCCGCGGGCTCCGGAATTCTGCTCGCGCCCGGATTCTGGACGAGGTCTTCCGCTGAGCGGTATCCGCTCGCTACTGTCCCCGCCATGCAAACGCCCCGTGGCAGCGTCGCCGCGGAGCGCAGCCGGTGTTTTGGCCTCGCCGGCGGGCTCTGCGCGCGATGCCGATGGGACCGGCGCCGCGAACCACGTGAGAGTGCCGCCGCGACTCGCCACTTAAGGAGTGGGTGTCGTGACCGCGGAGACCTCCCAGACGCTCGACCGGGGACTACGCGTCCTCAAGCTGCTCGCCGACACCGACCACGGTCTGACGGTCACCGAGTTGTCCACCAAACTCGGCGTCAACCGCACGGTCGTCTACCGCCTGCTGGCCACCCTGGAGCAGCACGCCCTCGTCCGACGTGACCTCGGCGGCCGCGCCCGGGTCGGGCTCGGCGTGCTGCGCCTGGGCCGCCAGGTGCACCCCCTGGTGCGGGAGGCGGCGCTGCCCGCGCTGCGCTCGCTCGCCGAGGACATAGGGGCCACCGCCCACCTCACCCTCGTCGACGGTTCGGACGCGCTCGCCGTGGCCGTGGTCGAGCCGACCTGGACCGACTACCACGTGGCCTACCGGGCCGGGTTCCGCCACCCCCTGGACAAGGGCGCGGCCGGCCGGGCGATCCTCTCCGCCCGCCAGGCCGGGGCGCTCGCCGAGCCCGGCTTTACCCTCACCCACGGCGAGTTGGAGGCCGGCGCGAGCGGGGCCGCGGCGCCGCTGGTGGGAGTCACCGGGATAGAGGGGAGCGTGGGCGTGGTGATGCTCGCCGACGCCGTACCCGAACGGGTCGGGCCACGGGTCGTGGACGCGGCGAAGGAAGTCGCCGACGCCCTGCGCTGAGCCGCGCCGGTCACGTTCGACGCCCCGCGCTGAGCCGCGCCCGCCCGGTGCGACGCCCTGCGCTGGACCGCGCCCGCCCGGTGCGACGCCCTGCGCTGGACCGCGCCCGGCCGGTGCGACGCCCTGCGCTGGACCGCGCCCGCCCGGTGCGACGCCCCGCGCTGAGCCGCGTCGCCCGGCTTTCGGGGGCGTCCGGGGCGGCCGGGTGCGTACGGATAGATTGGAGCCGTGCTCACTCGTCACTCCCGCCTCCGCAACCTCGCCATCGGCGCCGCACCGGTCGTCGCGCTGCTCGCCGTCGCCTGTTTCGCGCCGCTGCCGTTCGCGGTGGCCCAGCCGGGGCCGACCGCGAACGTGCTCGGGAACGACGAGGGCAAGCCGGTGATCACCATCTCCGGCGCGCCCACCCGCCCCACCAGCGGGCAGCTGCGGATGACCACCATCGTGGCCACCGGGCCCACCGCGGACGTCGGCATCGGCGATGTCGTCGACGGCTGGTTCCGCACCGACCGGGCGGTGATGCCGCGCGGCTCGGTCTATCCGGGCGGTGGCAGCGAGAAGGAGATCTCCGCGCACAACCAGGCGCAGATGAAGCAGTCGCAGGACGCCGCCTCCGTCGCGGCGCTCGGCTACCTCGGCCTCAGCCCCGACAAGGTCAAGGTCGAGCTGCACCTCGCCGACGTCGGCGGCCCGAGCGCGGGGCTGCTCTTCACGCTCGGCATCATCGACAAGCTGAACGGCGACGGCTCCGGAGGCGACCTCACCGGCGGCCGCACCATCGCCGGCACCGGGACGATCACCGGCGGCGGGGACGTCGGCGCGGTCGGCGGGGTCGCGCTCAAGACGCAGGCCGCGGCCCGGGACGGCGCGACCGTCTTCCTCGTGCCGAAGGGGGAGTGCTCGGACGCCGAGTCCGAACTGCCCAAGGGGCTCCGCCTGATCCCCGTCACTACGCTGAAGGGTGCGGTGTCCGCGCTTCAGGCGTTGCGGAAGGGCGACCCGGTCCCGTCCTGCTGACCGCGCCCGCGTCCATGTCCTTCCACGCGGGGAAGACGAGCGGGCTCAGCGTCGCCAGCAGATACACCCCGCCGACCACCAGGAGCGCGCCGCGCAACCCCGCGCTCTCCACCAGGAAACCGGCGGCGAGCCCGCCCAGCGGCATGGCCAGTTCGCAGCCCGCCGTGAGCACCCCGGCGACCCGACTGCGCAGCGCGTCCGGCACCTTCTCGTAGATCACCGTCGTCAGGATCGGGTTGAGCGAGCCGCTCGCGAGTCCCGCCACCACCATCGTCGCGGCCAGCGGCAGGGTGGTGCCGGTCAGCGCCGCGACCGCGTACCGGGGTGCCCCGCACAGCAGCACACAGACCGAGAAGACGGTGCGGCGCCGGAAGCGGTGGCCGACCAGGCCGTACAGGAGCGCGCCGGACAGTCCTCCCGCCCCGAACAGGGCGGCGAGCAGGCCGAGTTGGGGCGCGCCGCCCAGGTGGCGCTCGGCGTGGACGGGGAGCAGTACGGCGTTCCAGCCCTGGTCGGTTCCGTTCATCAGCATGACCATGGCGACCACCGCGATCAGCAGCCGGGTGCGCGCCAAGTAGGCGTATCCCTCGCGCAGTTCGGCCTTGTAGGTGCGTACGGAGACCGGTGGGGCGTCGCGCCGTGGCCGGGCCTCGGGGACGTGGCGCAGGCCGGCCGCGACCAGCGCCGCCGAGACGGCGAAGGTCGCGCCGTCGACGAGGAGTACGTTCCCGGCGCCGGTCAGCGCGATGAGCACGCCGGCCAGGGCCGCGCCGGTCATCCGGGCCCCGCGTGCGACGGCGTCGTAGCCGCTCGCGGCGCGCGACAGGGTGGTGCCGGACCGGCGCGCCAGGTCCGGGAGCAGGACGTAACGGGCGGTGACGCCCGGGGTGTGGGCGAGCCCGCCGAGCGCCATGAGGGCGCACAGCAGCCAGAACGCGAGCAGACCGGCCTGGTGCAGAAGTGGGATCGCGGCGACCGCGAGCCCGCACACGACATCGGAGCCGACCGACACCCGGCGGCGCCCGGCGCGGTCGATGACCGGGCCGCCGACCAGGGCCGACACGACGATCGGCAGCGTCGCGCAGAACGCGACGACCCCGGCCCGGCCCGGGCTGCCGGTGGTCTCCAGGACGAACCACGGCACCCCGATGAGGGTGAGTGAACTGCCGCTCGCGGATATGGCGTTGGCGGTGAGTACGGCCGTGAGCGGCCCCCGGTCGTGGTGTCCTCCCGGGCCACTGCGGTCGCGGTGTCCCCCCGGGCCGCTCATGCGAGGCGGGCTCGGTGCCGCGGTGCCTGCTGGGTCAGGCGCAGCCCCAACTCGACGAGTAGCCAGCCCAGTTGGGCCCGTAGGTGCCGCTCGCGGGGGAGTGTGGCGCGCGCTTCGGCGGCCAGCTCGGTGGCGCGCTGGTGGTGCATCTGGAGGTGGATGTCGCTGTGCACGGCGTGGGTCCCTTCGGGCGGGGCGGGAGACGGTGAGCGTGCGGGGGCCGGGTTCAGCGGGACGGATTGCCGCGCGGGAAGGAGTGGAGATGCACGCGGACCTGGGCGGCTTCGGCGTCCGACGGCGCGCCCGGGCCCGGGGAGAGGGTGCGGTACGACTCGACCACGGCGTGCAACTTCTCGTTCAGCTCGTGGAGTTGGGCGGGGGAGAGGTTCAGGGTGAAGTCGCTCAGGTCGCCGCTGGTGGACCACGGCTCCGGCCAGTCGTGCATGGTGGCGAGCCAGGTCGAGAGCTCCTGGGTGTGGATGCCGGCGATCTCGTGCAGGAACAGGTTGGCCGCGCCCCGCACCTCCGGGTCGCTGCTGGTGTGCAGGTCGTCGGCGAACGAAGTGCCGTTGTGCACGGCCTTCCACCAGCGCTCGCGCCCCTTGCCGCGCGCCGGGTCGTCCTCGACGAAGCCGTGCGTGGCGAGCTGGCGCAGGTGGTAGCTGGTCGCGCCGCTCGACTCGCCGAGCCGGTCGCCCAGTTGGGAGGCGGTCGCGGGCCCGTCATGGCGCAGCGACTTCAGGATCCGGATGCGCAGGGGGTGCGCCAGGCCGCGCAGGGAGCGCGCGTCGAGGATGCGCTCCCCTGCGGGGTTCTCGGGGGGCGGGGCGGCGGACCGCTTGTTCTCGGGCATGGCCCCAAGATAGCTCTGCAAAGAGACCCTTGCAACGCTTTCTTTGCATGAACTTCTTTGCATCGAGTGCTTTGCACGCCCGGCTCCCCGCGCTCCGGCTTGCGGTTGGCCCCGCGCCCCGGCCCGGCGGCCCGGGCCTCACCCCTTCCTGATGAACCCCTCCCGCACCAGCCACTCCAGCGCCACGTCGTGCGGGTCCTGGCCGTCCACGTCGACCTTGGCGTTCAGCTGCCGGGCGATCCCGGTCGTCAGCTTGGCGCTGAGCGGGTCGAGCAGGGCCGCGATCGCCGGGTACTTCTCGTACGTCCGGCTGTGCACCACCGGCGCCGCGTTGTAGTTGGGGAAGAAGTGCTTGTCGTCCTGGACGGTCGCCAGATTCATCGCCTGGATGCGACCGTCGGTGGTGAACACCTCGCCGAGCAGGCAGGAGTTGGACTTGGACACCTGGGTGTAGATGATCCCGGCGTCCATCTTCTGGATGTTGGAGGCGGGGACCGTCATCCCGTACGCCTTCTCCATGCCGGGCAGCCCGTCCTCGCGCGAGGCGAACTCGTTCTCCACGCAGATCGTCACCGCCGAGGGGTCCTTCTTGGCGAGGGCGGCCACGTCCGAGAGCGTCTTGAGGTGGTACTTGGCGTTGTTGGCCTGGCTGATCCCCAGCGAGTAGGTGTTGTTCAGGGTCGACTGCGGCAGCCAGGTCACGCCGTTCTTCAGGTCGGCGTCGCGCACCGCCCGCCACTGCGCCCCCGGATCGGTGATCGGCTTGCTGTTGCCCAGATAGGTGATCCACGCGGTGCCGGTGTAGTCGTACATCGCGTCGGCGTCGCCCTTCGCGATCGCCTCGCGGGCGCTGATCGAGCCCGGCAGGTTCGTCCGGTCGAGGACCTCGGCGCCGGCCGCCTTGAAGACCAGGCCGACCATCTGGCCCAGGACGATGTTCTCGCTGAAGTTCTTCGACGTGACCGTCAGGGAGGCGCCCTTCAGGGGCAGGCCCTTGCCGATCGAGCCGGGCAGCACGTCGTCCACCAGCGGGGAGCCGGACTTGAGCCCGCAGCCGGACACCACGGCGAGCAGGGCGAGCGAGCCGGAGGCGGCGAGCAGTGCCGTACGCGGGTGCCGCATCACTCCACCTCCAGTCCGCGCGGGGTCAGCGCGATCTCGGCCAGCGAAGCCAGCCAGTCCACGAGCAGGGCCAGGGCCACCGTCAGGATCGAGCCGAGGACCAGCACCGGCATGCGCTGGGTCTGGATGCCGGAGGTGATCAGGTCCCCGAGGCCGCCCCCGCCGCCGAACGTGGCGAGCGTGGCGGTGCCCACGTTCAGGACCAGCGCGGTCCGCACCCCCGCGAGGATCAGCGGCACCGCCAGCGGCAGTTCGACCTTGCCCAGGGTGCCGGGCGCCGACATGCCGATGCCCCGGGCCGCCTCGACCAGTTGGGGGTCGATGGCGCGCAGCCCGGCCACCGTGTTGGAGAGCACCGGCAGGACCGCGTAGATCACCATGCCGACGATCGCCGTGCCGGGCCCGATGCCGAGCCAGATCACCAGGAGCGCCAACAGGCCGATGGCGGGGGTGGCTTGGCCGATGTTGGCGATCGCGGTGACCAGGGGCGCCGCCCGGCTCACCCCGCGCCGGGTGAGCGCGATGCCCAGCGGGATCGCGATGAGCAGCACCCAGAACGTGGAGATGGCGGTCAGCTTCACGTGCTGCCAGAGCCGGAGCTGGACGTTGCCGTTGTTCAGGGAGTTCTTGGCGATCGTGTCCAGGTGGACATGGGTGATCCAGAGGTAGGTGATCACCAGGACGACCGCGAGCACGACCGGCAGGAAGGCCAGTTTGCGCCAGGTGATCCGGCGGGCCGGCCGGTCCGGCGCCGGGCCGGTCTCGTGTTCGGGCTCGGGTTCGTCGAGCGGGCCGGGCAACTCGTCGCGGAAGGCGTGGCCACCGACCTCGTGCTCACCCGGCGGACGCTCGGCGGGGGCGGGGCTCCTGGGCGTCATGGCTGCGTCGCACCGCCCTCCAGCTCCTGTTCCGTCTGGTGGTGGCGGAGCTCTTCGAGGTCGTGCTGGTGCTCGATGGCCGCGAGCCGGTCGGCCTCCAGGAGTTCGTGCACGGAGTTCATCAGGGTCTCCATGTCGACCACGCCGATGTACTCGCCGCGCCGCCCCGTCACCGCGACCCGGCCGCCGGAGTCGATGAGCACGGCCTCCAGGGCGTCGTGCAGCGTCGCGCCCCGGGTCACGGTGTCGTGCACCATCTGCCCGGCCCGCGCGAGCGAGCCCTTGGCGCGCATCAGGTCGCCGCGCCGCAGCCATTTGTAGGGGCGGTTCCTGCGGTCCAGCATGAGCAGTTCGTTGTGCGGGCCGCTGCGGAGCTTGTTGAAGATCGACTGGGGCGGGTCGTCCACGGTGACCGTGGGGAACTCGGCCATCTCCACATCCCGTACGCGGGTGAGGTTGAGGCGCTTGAGGGCGGCGCCCGCGCCGACGAACCCGGAGACGAAGTCGTCCGCCGGGTTGGTGAGAATGGCCTCCGGAGTGTCGAACTGAGCGATGTGTGAGCGTTCGCGCAGAACCGCGATCCGATCGCCCAGTTTGATCGCCTCGTCGAAGTCATGGGTGACGAAGACGATCGTCTTGTGCAGCTCGTGCTGGAGGCGGATCAGCTCGTCCTGGAGGTGGTCGCGGGTGATCGGGTCGACCGCGCCGAACGGCTCGTCCATCAGGAGCACCGGTGGATCGGCCGCCAACGCCCGTGCCACGCCCACCCGTTGCTGCTGTCCACCGGAGAGCTGGCGCGGATAGCGGCCGTGGAACTCGCGCGGATCGAGCCCGACCAGGTCCAGCATCTCCTCGACCCGGTCCTTCACCCGGGCCTTGGACCAGCCGACCATCTTCGGGACGAGCGCGATGTTCTCGGCGACCGTCATGTGCGGGAAGAGCCCGGACGACTGGATCGCGTAGCCGACCTTGCGGCGCAGTTTCACCGGGTCGATGTCGGTGACGTCCTCGTCGTCGATCCGGATGCGACCGGATGTCGGTTCGATCAACCGGTTGATCATTTTGAGGGTGGTCGACTTGCCGCAGCCCGAGGGGCCCACGAAGACGACGGTCTCGCCCGCCTTGATCTCCATGGTGACGCTGTCCACGGCCGGCTCCGCGCTGCCCGGATACCGCTTGGTGAGCTCCTCCAGCTGAATGGAGGCCCCCGAGGTCGAGGCCTTCGCGGTCGACGCGCCGGCGGACTCGGACCGCTCGGACTCGGATCGCTCGGACTCGGATCGCTCGGACTCGGATCGCTCAGACACGGATCCCCCTCGGGATGGTGAGACGGCCGATCAGTACGTACGCCGCGTCGAAGAGCAGGGCCAGCACCACGATGCCGAGGGTGCCCGCGAGCACCTGGTTGATGGCGTTGGCGCTGCCCAGCGAGGCGATCCCGCGGAAGATCTCGTTGCCGAGCCCGGGGCCCGAGGCGTACGCTGCGATGGCCGCGATGCCCATCAGCATCTGCGTGGAGACCCGGATGCCGGTCAGGATCGGCGGCCAGGCCAGCGGGAGTTCGACCCGCAGCAGCCGGGCGGGGCGCGACATCCCGATGCCCTTGGCGGCGTCCACGAGCGAGGGGTCGACGCCGCGCAGGCCCACGATCGCGTTGCGCACGATCGGCAGCAGCCCGTACAGCGTCAGGGTGACGACGGTGGGCGCCACCCCGAGGCCCACCAGCGGGATCAGCAGACCGATCATGGCGAGCGAGGGGATGGTCAGGACCGTCGAGGTGGACGTGATCGCGAGGGCCGCCGCCCAGCCGCTGCGGTAGGTCACCACCCCGATGAGGATGCCGAGCACGGTGGCGATCACCATGCACTGGAACACGGCGCTCGCGTGCTGGAGGGCGTCGGTGAGCAGCTGTTGGTGCCGGCTGGACAGATAGTCCCAGAAGCCCACGCGCTCAACCCCTGTCGGTCCTCGGTCAGCCCCCGCCGGGCACGGAGTCCTGACCCGCCTGCTCCACCAGCGGGATGATCCGCAGTGGGACCGGGTTCTCCATGACGATCGCCGTGGAGGCCCGGACAATGCCATCAAAACCGACAACCCGGTCGATCACCCGCTGGAGATCGGCGTTGGAACGGGCCACGAGACGGCACAGCATGTCGCCGTGGCCGGTGGTGGTGTGCAGCTCCAGGACCTCCGGCACGGACGCCAAGTGGGCCCGCACGTCCGCCCCCTGGCCCTGTTTGATCTCCAGCGTGGCGAACGCGGTGACCGGATAGCCGAGCGCCGCCGGGTCGACGTCCGGGCCGAAGCCCCGGATGACTCCATTGGACTGAAGCCGGTCGAGCCGCGCCTGGACCGTGCCGCGCGCCACCCCGAGCCGGCGGGACGCCTCCAGGACCCCGATCCGGGGCTCCCGGGCGAGCAGCACGATCAGCCGCCCGTCCAAATGATCGATCGCCATGCCCGCCTCCGGATGGTCATCATGTACAGAACGCCCTCCCATCCTGGCTCTCCACTGCACAGACTGACCAGTGAAAATGCAAACTATTGCGCAGCCTGCCACCCGGGGCGACCCTCCTTCCATGACTGAGACCATCGATCACACCCCCGAAACCGCGCGGCAGGCCGACCCCTTCCCGGTGAAGGGCATGGACGCGGTCGTCTTCGCCGTGGGCAACGCCAAGCAGGCCGCGCACTACTACTCGACGGCCTTCGGCATGAAGCTGGTCGCGTACTCCGGGCCGGAGAACGGCAGCCGCGAGACCGCGAGCTACGTGCTGACCAGCGGCGCCGCCCGCTTCGTGTTCACCTCCGTCATCAAGGCCACCAGCGAGCGGGGCCGCTTCCTGGCCGAGCACGTCGCCGAGCACGGCGACGGCGTGGTGGACCTCGCCATCGAGGTGCCGGACGCGCGGGCCGCGTACAAGTACGCCACCGAGCACGGCGCCACCGGTCTCCAGGAGCCGCACGAGGTCTCCGACGAGCACGGCACCGTCGTCCTCGCCGCGATCGCCACCTACGGCAAGACCCGGCACACCCTGGTCGAGCGCTCCGGCTACGAGGGCCCCTACCTGCCGGGCTTCGTCACGGCCGCGCCGATGGTCGAGCCGGTCGAAAAGCGCTTCTTCCAGGCGATCGACCACTGTGTGGGCAACGTCGAACTCGGCAAGATGAACGACTGGGTGGCGTTCTACAACAACGTCATGGGCTTCACCAACATGAAGGAGTTCGTGGGCGACGACATCGCCACCGAGTACTCCGCGCTCATGTCGAAGGTCGTCGCCGACGGCACCCTCAAGGTGAAGTTCCCGCTCAACGAGCCGGCCATCGCCAAGAAGAAGTCGCAGATCGACGAGTACCTGGAGTTCTACGGCGGCCCCGGCGTCCAGCACATCGCGCTGGCCACCAACGACATCGTCGCCTCGGTCCGCGCCATGCGCGCGGCCGGTGTCCAGTTCCTCGACACCCCCGACTCGTACTACGACACCCTCGGCGAGTGGGCCGGCGAGACCCGGGTGCCGGTCGAGACGCTGCGCGAGCTGAAGATCCTGGTCGACCGCGACGAGGACGGCTACCTGCTCCAGATCTTCACCAAGCCGGTGCAGGACCGCCCGACCGTCTTCTTCGAAATGATCGAGCGGCACGGTTCGATGGGATTCGGCAAGGGCAACTTCAAGGCCCTGTTCGAGGCGATCGAGCGGGAGCAGGAGCTGCGGGGCAACCTCTGACCTGCAACCTCGCGCGTCCGTACGGTAATTGAGTTACCGTCATGAGTCAGCGGCCCCACGGACCTGACCCGTGGGGCCGCTGTCTTGCCGCTGTCTTCGAGCCCGCCCGGTGCCGCCGTCAGCGCCGCTGCGAGGGCTTCGCGGGCTTGGCGGGCCGGGGCTTGGCGGGCCGCCTGGCCCCCTGGCTCGACTGACCGGACTGGTTCGACGACGCGTCGGACGACGCGGAGCTCTCGCCCCCGGAACCGGAGCCGGAACCCGACCCCGACCCCGATGCGGCGGCCGCCACATGGCCGTACATGTCCCGGGGGCCGCCCTCCGGCGGCTCGCCGAGCGCCGTGAGCGCCTCCTTCGCCTTCGGCGCGAGCACCGGCGAGAAGTACGGATTGGTGCGCAGCGCGTCCTGAAGATGACGCCGCGCCGCGCCCGACTGCCCCAACTCCCGCTCGATCACGGCCTGGTGATAGGAGAACAGGGCGCTGCGTACCCCGGAGTCGGTCGCCTTCTTCGCATGCGTCAGGCCCTCCTCCGACTCGCCCGCCCGGTACATCGCCCAGCCGAGCGCGTCCTCCACGGCCGGGCTCGGATGCGCCTTCCACTCGGCTTCGAGCCGGTCCACCGCCGCGTGCGCCGACCCGTGATCGGCCTCGTACCGGCCCAGCACCAGAGCGTCGTCCACCCCGTTGGAGCCGTCGCGTGCGGCCAGCTCCTGGAGCTTGTCGAACCACGTGCGCGCATCCCCGTCCAGGCCCTGGGACTCGTACAACTCGCCCAGTTCCAGCAGGTATTCGGGGCGAGGCAGTACCGCGACGGCCGCCAGGTAGTCGCGCTGGGCGTCGGCCTTCTTCCCGAGCGCGGCCCCGGCCCTCGCCCGGCCCGCGAGCGCGGCGTGCGCGCCCGGGTCGGTGCGCAGCGCCGCCTCGTAGCGCGCGAGGGCCGCTTCCGGCTCGCCCCGCTCCCACGCCAGGTCACCCGCCGCCACCAGCGAGGCCGCCTTCTGCACGGGCGAGGTGGCGTGCGCGACCGCCTCGTCCAGGGCGACCGAGGCGTCCTCGCGCCAGCCGTGCGCCCGGTAGACCTCGGCGGCCTGGGTCAACGCGGCCGAACCGTCGCGCAGTTCGAGCAACCGCTCCACCGCCTTGGCCGCGCCCTTCGCGTCACCGAGTCCGTTGTACGCCTCGATCAGCGGGGGGTACAGCGTCCAGCGGTCCGCCTTGCGGGCGCGTACGGATTCGGCCAGGGTGCGGGCCGCCGCGTAGTCGTGCCGCGCGTTGGCGAGGGCCGCGAGCCCGATCTCGGCGTCCAGGTTGTCCTTGGGCCGCACCTCCAGCGAACGCCGCAGCGCCCACTCGGCGCGCGGATAGAACGAGGAGTCCGCGCCGCGCACCCCCCGCTCCAGATAGGCCGAGCCGAGCACCGCCCAGGACGCCTCGTCCTTGGGGTGGGTGCGCACCCAGGCGGCCCGGTCGGTGATCAGCGCCGTCACATCGGCCACCGAGGCGGGCGCCCCACCGGTCACCGCCGTCAGGGCCCGGGCCGCCGGGCCGGGCGCGGGTGGCGGCGCCTTCGGGCCCGGGTCGTCCGGCATGATCAGCACGACGCCACCGATCAGCACGCCCGCGGCCAGCGCCACCCGTACGGCCCGCTTCAGAGCCTTGGGCGGCCCCGACCGGGGGGAGGTCCGCCGGGCCGCGGCCGAGGCCGACAGCCACGCCGCCCGCCGAGCCGCGTCCGCATCCTGTTCGGTCTTCGCGATCTCCATGGCGCTCACTGTGCGTCAATACGAAGAGCGCACCGCGCACCGCCCGACCGGCCGGGGAAAGGGTTCACACCGATGGCCCCGGGTGCCAGGCTGAGGGGATGGACGATCTTCTCGTACGGCTGCGGGAGCACCTCCCGGCGGACGCCGTCATCACCGACCCCGACATCACCGGCGGTTACGCCCACGACATGGCGAGCTTCTGCGCGGCGGGCACCCCGGCCGTGGTGGTGCTGCCCCGCACCGTCGAGCAGGTCCAGCACGTGATGCGCACGGCGACCGCGCTGCGCGTGCCCGTGGTGCCGCAGGGCGCCCGCACCGGCCTGTCCGGCGCGGCCAACGCCAGCGACGGCTGCATCGTCCTGTCGCTGGTCAAGATGGACCGCATCCTGGAGGTCAACCCGGTCGACCGGGTCGCGGTCGTCGAGCCCGGCGTCATCAACGCCGTCCTGTCGCGCGAGGTCCAAAAGCTGGGGCTCTACTACCCGCCGGATCCCTCCAGTTGGGAGATGTGCACCATCGGCGGGAACATCGGCACCGCGTCCGGCGGCCTGTGCTGTGTGAAGTACGGGGTGACCGCCGAGTACGTCCTCGGTCTGGAGGTCGTGCTCGCCGACGGGCGGCTGATGAGCACCGGCCGGCGCACCGCCAAGGGGGTCGCCGGATACGACTTGACCCGTCTGTTCGTGGGCTCCGAGGGCAGCCTCGGCATCGTTGTCAAAGCGGTGCTCGCGCTGCGGCCCTCGCCGCCGCCCCAACTCGTGCTCGCCGCCGAGTTCGCCACCGCCGCGGCCGCCTGCGATGCCGTCGTACGGATCATGGAGCGGGGCCATACCCCGTCCCTCCTTGAACTCATGGACCGCACCACCATCCAAGCCGTCAACCGCATGGCGCACATGGGCCTGCCCGACAGCACCGAGGCGCTGCTGCTCGCCGCCTTCGACACCCCGGACCCGGCGGCCGACCTCGCCGCCGTCGCCGAGCTGTGCACCGCCGCGGGCGCCACCCAGGTGGTCCCGGCCGAGGACGCGGCCGAGTCCGAACTGCTGCTCCAGGCACGCCGGTTGTCGCTCACCGCCCTCGAAACGATCAAATCGGCCACGATGATCGACGACGTGTGCGTTCCCCGATCGAAGCTCGCCGCGATGATCGAACGGACATCGGCGATCGCCGCCAAGTACGACTTGACCATCGGCGTCTGCGCGCACGCGGGCGACGGCAACACCCACCCCGTGGTCTGCTTCGACGCCGCCGACGAGGACGAGTCGCGGCGCGCCCGCGAGTCGTTCGACGAGATCATGGCGCTCGGCCTGGAACTGGGCGGCACCATCACCGGTGAACACGGCGTCGGCGTACTGAAGAAGGAGTGGCTGGCCCGCGAGCTCGGCCCGGTCGGCATCGAGATGCAGCGCGCGGTCAAGCACGCCTTCGACCCGCTGGGCCTGCTCAACCCGGGCAAGCTGTTCTGAGCGCGGGTCCGCGGGGGGCGTGCTTGGGGTGCGATTCGTACTGAGTACGTGTTCGGTCCGCTTGGGCCGGGCGAGCTGATCTGTGCCCGGGCCGTCACGGGCCGTCCTTGGGGTGCGATTCGTACTGAGTACGTTGTCGGCCCGCTCGGTCTGCTCGGGCCGGGCGGGCTGTTCTGCGCCCGCGGCCTCACGCGCCGTCCTCCGGGCGGGATTCGTCCGAGGGCCACGGGTCGCGCAGCCACAGCTCGTCGGTGCCGCGTCCGGTGGCCGGCGCCAGCAACTCGGCGAGGCCGTCGTCGATGCCGAGCCGCTCGGTCTCGGACCCCGGCGGCACCGCCCGCAGCGTCCGCTCCAGCCACGCCGAGACCTGGGCGGACGGCGCCTCCAGCAGCGCGTCGCCGTCCGGTGAGCTCAGCGCCATCAGGACCACGTTGCGCCCCTCCACCTTCGTCGGCCAGATCCGTACGTCCCCGTGCCCGCACGGCCTGAACACCCCCTCGACGAGCAGCTCGCGCGCGAAGGTCCAGTGCACGGGGGTTTCCGAGCCGACGTGGAAGGTGATGTGCACGGCGTAGGGGTCGTCGGTGCGGTAGGTGAGCCGGGCCGGTACGGGGATGCTGCGCTCGGGCGACAGCACCAGCTTGAGCTCCAGTTCGCGTTCCACGACGGTCTGCATGTGGCGTCCCTCTTCTCTTCCCTGTACGGGGCGGTACGGGAGCCCGGGGTGGGCCGTATCGGGTGAGAGCGGGTTGCGGGGCGGGCATTACGCGACTCCGGGTAAGTTTTTTGGGGCTGCGCCCCAAGCCCGGCGGGTCCGCCCACCCGCCCACCCGTGCAGGGGGTTGGTTGGTTCCGGCCCCTGGGGCTCCGCCCCAGACCCCACGGGTTTTCCCACCCGCCCACCCGTGCGGCGGGTTGAAGGGTTCGGCCCCTGGGGCTGCGCCCCAGACCCCCGCGGGGGCTCTGCCCCCTGCACCCCCGTTCGCGCCTGAACGGCGCTCGTCCTCAATCTCCCCCAAGGCCTTAAGGGCCAGGGGGGACCCCCATGACGGGCTGGGGTGCCGGCCAGCACCGAGCACTTAAGGGGCGCGGGGAACTGCGCGACCAGCCACCCCCGGCCCGCAGACGAAAACGGGTTCTTCAAAAGCGACCACGGCCCGCAGGCCAAGAACGGGGTTAGGGGCGCGAGGAACTGCGCGAGAAGCGACCACGGCCCGCACACGAAAGGGGGTTTTGGGGGCGCGGGGAACTGCGCGACCAGCCCCATGCGGCCCGCACACGGAAGGGGTTGGAGGCCGAGGCGCGGCCAGGACCCGCACGCGGAAGGGGGCCGGGGGCGCGAGGCCCGGGCAGGGCCCGCACGCGGGAGGGGGCTAGCGGCGCGGGAGGGGGCCGGGGGCGCGGGCGCAGGGTTGGGGGTGCCCGCCGTTACGGGGGCCCCGAGCCGTTTAGCCAGGTTGCGCCGTATACCGCCGACGCCACCGACAGCGCCCCCACCACCCCCACCGCCCCCACCCCCCGCATTCGGGAAAGCGCGACCGCCACCGGCAGCAGCAGAGGGAACGCGGGCAGCAGCAACCGCGGCTTGGAGCCGAAGTAGCCCGAGGAGCACAGCGCCAGGGCCATGACGATGCCTGTGTAGACGAGCAGGGGCAGCGGCTGGCCGCCCCGCACGCACGCCCCGTACGCCCAGAGCGCCAGCGCCGTGCCCGCGATCATGCCGAGCCCGGCGAGTACGACGGGCCAGCCGCCGAGGTGGTCCACGATGAACTTCCCGTAAGCGAGGCCCCCGTCGAAGCCGTTGCCCCACTCGGCCTGCACGTGCAGATAGCCGAAGACGCTTCCTCGCCGGGCGCCGACCCAGAGCACATAGCCGGCCGCGCCGAGCGGCGCGAGCACCGCCCCGGTGAGCAGCCGCGCGTCCACGCGCCGGGTGCGTCGCGCCTCGACGACGGCCCCCGCCCACAGCGCGGCCGCGACCGCGAGTCCCACCGGGCGGGTGAGCCCCGCGAGGGAGGCGAGCAGCCCGGCCTCGACCCAGCGCCGCCGGAGCACCGCGTACAGCGCCCAGGCGGCCAGCGCGGTGAACAGGGCCTCGCTGTACGCCATCGACTGCACGATCCCGACCGGAACGGCCGCCCACACCGCCGCGAGCAGCAGCCCGGCCCGGTGACCGTGCAGGTGACGGCCCGTCAGATACAGGGCCCACGCGGCGAGCGGTCCCGCGACCGCGCTGACCAGCAGACCCGCGTCGCCGGGGCCGAGCGGGGTCACCGCGGCGAGGGCCTGTTCGAGCCAGGGGAGCAGCGGGAAGAACGCGAGGTCGGACAGGACCCTGCCGTCGGGCGCGGTCAGCGTGAAGTCGTAACCCGACTCCACGACCCGCACGTACCAGAGCGAGTCCCAGCGCGCCGACAGCAACGCGTGGGCGTCCTTGTCGTTGGCCCGGGACCACAGGACGAGGGCGAGGAGGCCGAGCGCGCGGATCGCGGCGAAGGCTCCGACCGCCGACCAGGCGCGCCGTGCCACGGGCGCCGCTGAGGAGAGGGCCGCCGAGGAGAGGGCCGCCCGTTCGCCGCGGCCGGTCGGGCCAAGCCCCACGCTCATCGCCCACTCGCCTTCCTGACCGACCGGGCCGGGTGCACCAGTTCGAACCGCAACGACTGTACGCACCGGCGCACCCCCGCCGTGCGGCCCGGTCCGGTATCACACGCGGCCCGCGCATCGCTCGTACGCGGGCTTCCTGCCCGGCTTCCCCCCACCGGGCCCCGGGTTCTTGGTTAGGGTCGCTCCGACGGGACCGGTCGGGCGCCGGGGTTTTCGACGTGCTGGGCGGCGTCCGGCACGTACCGGGGCACCACGGTTCGGCGGGACCCGTCGAGCAGGCCCTAATGTCCTCCTGGGACAAGCGGAAGCGCGCGGTCGGCACCCGGTCCGGCCGGTGTTCCGCGGCAGAGGTCAACTGTGGTGGATCGAAACGGAGTTGGGGACATGGCGACGGTTCCTTCTGACAGCGACGGGAGCGGAGCCCGGGAAGGGTATTACCCGGACCCGTCCATTCCCGGATATGTCCGGTACTGGAACGGGGTCTCCTGGGTGCCCGGCACGAGCCGGCCGGCCCCCGCCGCGGGTGAGGCGCCGCCCACCCCGCCGCTCGGCGCCACCCCCGCCCCGGCCCCCTCGCTCGCCGCCGCGCCGCCCGTCACGGCCGCCCTCGCCGAGGAGACGGGCCCGGTCTTCCTCGACGAGCCCGAGGCCTCGCCCGCCTCCGCGCAGGGCTCCGCCGCGCCGCAGCCCGCCTGGCACGCGGACGCCGCCCACCAGTCCGGCTTCGGCGGCGACCAGGACCGTCGGGTCTCCTGGGGCCAGTCGGTCGATGGGCGCGCGCTCCCGGAGTCGGCCGACCCGCGGCAGTTGCCCGACCCCCGCCGTCTGCCCGACCCCCGCCGCGCGGAGCCCGCACGGCCCACGCCCACCGGCCCCTCGACCGGCCCCTCCACCGGCCCCTCGACCGGCCCTTCGACCGGCCCTTCGACCGGCCCTTCGACCGGCCCTTCGACCGGCCCTTCGACCGGCTCCTCGACCGGTCCCTTCGGGGACCCCGCGCGGCCCGCCGGCACCGTGCCGCACCAGAGCCCTCAACAGTCCGCCCAGTTTGCCCAGTCTGCGAACGCCGCCCAGTCTGCGAACGCCGCGCACCCCGCACCCTCCGCTCACTCCGCGAACTCGGCCCGAGCCGCGCGACCCGCCCAGCCCATCCAGTCGGCCCCGCCCATCCAGCCGGCCGCCCCGTTCGCCGGGACCGTGCCGCCGACGGCCGTCGAGCCGGCTCCCGTACGGCCCCAACTGCCCACCCCCGCCGACCCCGTCGTCGCCGCGCCGACAAGCCCCGCGTACTCCGCGCCCGCGACCCCACAGCCCCAGCCCGCCCAGCCCGCCCAGCCCGGTCCCGTCGAGCCCCACCCCGGCCTACCCGGGTCGCCGATGACGGACGGGCCCGGGGGAGGGGCCGCGTCCTGGGCGCAGCAGGTGCACCGGCTCGCGCAGCCCGACGCGCAGGCGCAGGAGCCGGTCGTACCGTGGAAGCCCCCGGTCGACGACCCGTTCCTGCGGGCCGCCCGGGAGCAGGCCTCGGCCAGACCCGCCGGCCTGGTCAGACGGCTGATCGCGCGGCTCGTCGACACCGCGCTGCTCGGCGCCCTGGTCGCGGGCCTCGCCGTACCGCTCCTGGCCCGGGTCGCCGACCACGTCCAGCAGAAGATCGACGCGGCGAAGCTGTCGGGGCAGACGGTCACCGTCTACCTCCTGGACGGCACGACGGCCGGCCTCCTCGGCATCGTCCTCGGCGCGTTCCTCCTCCTCGGCCTGCTGTACGAGGCGCTGCCCACCGCCAAGTGGGGCCGCACGCTCGGCAAGAGGCTGTGCGGGGTGCAGGTGCGCGGCATCGAGTCGTACGAGCCGCCGACGTTCGGCCAGGCGGTGCGCCGCTGGCTCGTCCACGGTGTGCTCGGGCTGCTCGTGATCGGCGTGGTCAACGTCGCGTGGTGCCTGTTCGACCGCCCCTGGCGCCAGTGCTGGCACGACAAGGCGGCCCACACCTTCGTGGCGCAGGGATGACTCCGAGCCCCGGCCCGTTCGCGGCGCGGGGGGTGGGGGGCGGGGTCCGCGGGAGGGGCCGGCCTCTTCGGGGGCGGGGGGCGAGCCTCCCCCGAACGGCGTCCCTCCGGTCGCGGTCGCCACGCGCGCGCGTTGCACTACCGGCATGAGTACCGATCAGCCGCCGCCCGGTCAGCCGCCCGAGGACGACCCGTTCCTCAAGAAGCCGTCAGAGCCTCCGCGGAGCGGTTCTCCCTACGGCGGCACGCAGCCGCCCCCGGGACGGCCGCCCGGTGACTCCCCCTACGGTGCGGGCCCGCCGTCCGGCGGTGACGGCCCGTACGGCGCCCCGCCTCCGCCGTCCGGCGCGGGTGGCCCGTACGGCGCCCCGCCTCCGCGGTCCGGCGCGGGTGGCCCGTACGGCGGGCCGCCTCCCCCCGGTGGCGGTTCGCCGTACGGCAGCGCCCCGCCACCGCCCTCCGACCCCTACGGAGGTCAGTACGGCGGTGTCGACCCGCTGGCCGGGATGCCGCCGCTCGCCGACTTCGGCAAGCGGTTCCTGGCCCGTTTCATCGACTTCCTCATCATCGCGATCCCGCTCGGCCTGATCGAGTGGGCGACCAGTAACCGGGTCGTCATCTCCACCTCGGACAACGGCGACTCCGGTACCGAGGTGATCAGCAAGGCGTACTCCGGCAGCGGACTGCTCTGGCTGCTGATCACGCTCGTGGTCTACATCGGCTACGACACCCTGATGGTGTCGAAGTCCGGGCAGACGCTCGGCAAGAAGCTGTTGGGGCTGCGGGTCGCGATGCTCAACGACGGGAGCGTGCCCACCACCAACGCGGCGCTCGCCCGGGCGGCCGTGCTGTGGGCGCCGTTCGTGCTCTGCTGCTACTGCCTGTGGGACATCATCCTGGGCATCACGATCGTGACGGACAAGCCGTACCGACAGGGCTGGCACGACAAGGCCGGCAAGACGGTGGTGGTCTCAACTCCGCAGTGAGTGCTGGCGGGTCGACGCCCGCCGCTCGCGAGGGGCCGGAACGCTTCCCCACTGCCCCGACGGCGAGGCGGCGGCCCCCGCGGCGGACGTCTCGACGACGGCCGCACGGTTCACCGGTGCCGCACCCGCGGCCGGGACCGTGCGGCCGTCGGCGTTGGCGTGCGCATCGGCGCGCGTCCGGCGGGCCAGTGGCATGGGGACCGTCACGGCGACGAGCAGGCCGAGGAGGAGCGCGGCGAGGACGATGACCGCCACCCCGACGCCGGACTCGGTGCGGGAGAGCAACAGCATGGCGACGGTCGAGAAGACGACGGTGGCCGAACCGTAGGAGAGCTGTGCGGCAGTGGGACGCGGCATGGCGTTATCCGTCCTCATGGTTCGGATAGGGGGTGAGCCTCTCGACCGTTCTCAACCGGCGGCGGGCCACCGGATCGCACTGCCAAGCGACTCTACGTCGGTCCATGCCCGAGCGGAACTGTTGGTAAGCGTGACCTAACCCACGGTGCCGGTGCACAGGGGGCGCACGGAGTCATTCCCCGAAGCGACCCCGTCCGGATGTCGAGATGTGTGCACCCGATGTCCCGGTCTGTTACCACATCCGTCACGTTCGGATAGCGGAACTCCACTTCTGCATAATGTACTTGGCACGAACAAGTCAAGATCTGTCTTTTCCTTGGTAACTCCGGTCCAATGTCGTCACTTGAGACGCGTGTCGAGCACCGGAACCAGCCCCTCACCCCCCGGTTCGTGCCGGCCGCGGGGGAGGAAAACGTCAAGTGACCAGCAGCAGGAGGGCGGCCAGAGCCGCCGCCGTGCTCGTGGCCCTCGCCACGGCCGGCGCCACGGGCTCGGCATACGCCACGGCCCAGGCCGACTCGAAGGCCCCGGCGCCCGTTCAGCGCCAGGACCCGTCGAGGGCCAACGGCCAGGAGCACAACCTCAAGGGCCCGTTCAGCGACCAGCAGGCCCAGCAGCGCCAGGCGGCGCTGGAGCAGGTGATCTCCGGCAAGAAGAAGGTCGAGAAGCGCGGCGCTTCCGACGTGGTCAAGCTCAGCGACAAGAAGTACGTCGAGCTCGGCCGCGAGAAGACCGACAAGATCTTCACGATTCTGGTGGAGTTCGGCGACCAGGTCGACAACACCACGATGTACGACCCGGACGGCCCCGACGGCCCCAAGCCGCCGCAGCCGAAGTACGGGGGCACCCCCGGCCCGGCGCACAACCAGATAGCCAAGCCGGACCGTTCGAAGGACAACTCGACGGCCTGGCAGGCGGATTACAACCAGAAGCACTTCCAGGACCTGTACTTCGGTACGGGCAAGAACGTCAACTCGCTGAAGACGTACTACGAGAAGACGTCCTCGGGTCGCTACTCGGTCGACGGTCAGGTCACCGACTGGGTCAAGATCCCGTACAACGAGGCCCGTTACGGCTCCAACTACTGCGGCCAGACCAACTGCGCCAACGTGTGGGACACCGTCCGTGACGGCGTCAACGCCTGGGTCGCCGACCAGAAGGCCAAGGGCCAGACGGACGCGCAGATCAAGGCGACCCTGGGTCAGTACGACCAGTGGGACCGCAACGACTACAACAACAACGGCAACTTCAACGAGCCCGACGGCTACATCGATCACTTCCAGATCGTGCACGCCGGCGAGGACGAGTCCGCGGGCGGCGGCGCGCAGGCCACCAACGCCCTGTGGGCGCACCGCTGGTACGCCTACGGCACGGACGCGGGCAAGACCGGCCCGGCCAACAACAAGGCCGGCGGCACCCAGATCGGCGACACCGGGATGTGGGTCGGCGACTACACGATGCAGCCGGAGAACGGCGGCCTCGGCGTCTTCGCGCACGAGTACGGCCACGACCTCGGTCTGCCGGACCTCTACGACACCACCAACACCGCCGAGAACTCGGTCGGTTTCTGGTCCCTGATGTCGGCGGGCTCCTGGCTCGGCACCGGCAAGGACTCCATCGGCGACCTGCCCGGCGACATGACCGCGTGGGACAAGCTCCAGCTCGGTTGGCTCGACTACGCCTCGGTGAAGGCGGGTTCGAAGATCACCGCCAAGCTGGGCGTCTCGGAGTACAACACCAAGAACAACCAGGCGCTCGTCGTCGAGCTGCCCAAGAAGGAAGTCACCACCACCGTCGTCAAGCCCGTCGAGGGTTCGAAGCAGTGGTGGAGCGGCATGGGTGACAACCTCAACAACACCCTGACCCGCTCGGTCGACCTCACCGGCAAGTCCAAGGCGTCCCTGGACCTCTCGGGCTGGTGGGACATCGAGAAGGACTACGACTTCCTCTACACCGAGGTCTCCACGGACGACGGCGCCAGCTGGAACGCGATCGACGGCACCGCCGACGGCAAGGCCATCACGCGCGACTCCAGCGACAAGCCGGCCCTGACCGACGCCTCGGGCGCGTACAAGAAGCTCTCGTACCCGCTCGACCAGTACGCGGGCCACAAGATCCAGCTCCGCTTCCGCTACCAGACGGACGGCGGCGCGGGCGGCAAGGGCTTCACCGCCGACGCCATCAGCGTCACCGCCGACGGCACCGCGGTGGTCACCGACGGCGCCGAGGCCGGCGACAACGGCTGGGCGGCGAAGAACTTCACCCGCATCGGTGAGTCCTTCACCAACGACTACCCGCAGTACTACCTCGCGGAGAACCGCCAGTACGTCTCGTACGACACGACCCTCAAGGTCGGCCCGTACAACTTCGGCTTCTCCACGACCCGTCCGAGCTGGGTCGAGCACTACCCGTACCAGCGGGGCCTGCTCATCTGGCTCTGGGACACCTCCCAGAAGGACAACAACGTCTCGGCCCACCCGGGCCAGGGCCTGATCCTGCCGGTCGACGCGCACGCCAAGCCGCTCAAGTGGGCCGACGGCACGCTGCTCCGCAACAAGATCCAGCCGTTCGACGCGCCGTTCAGCCAGTACCGGACGGACGCCTTCACGCTGCACAAGGCGGACGTGGCGACGAAGATCAAGTCGCAGGCCGGCGTCCCGGTCTTCGACGACCACCAGGGCACGTACTGGTACGCCGAGAACCCGACGGGCAGCGTCAAGGTTCCTGACACCAAGACGCGGATCTCGATCGTCGACCAGCCGTGGAACGGTCAGACGATCACGGTGAAGGTCGGCACCTCCACCAAGTAATTGCTGAACCCGCAGGTCAAACCATGATCGGCCGTCGCCCTCTAGCGGGCGGCGGCCGATCGTGTTTAGGTGCGTCCTACGAGTCCTTATTGACAGTGGGGTCGGCGCGGCACCGGTCGCGGGGCCCGACACAGCGTCTTGCAGGGGGAGTGGTCCGGCATGCCCGGCGGAGGTTATTGCAAGTTGCCAGGCGGCAGCGTGGTCGTCGCCCTCACGCTGCCGAACCCGGCCGCGCCCGGCAGTGACGTGCGCGTCCTGGTGCACGCCGTCAACCGCGCCCGAGCCCTGACCAGGCTCCGCAACCTCGGGTTGCGCGCGGTCTATCTGCGCGGCCAGACCGAGCCGCCGACGCTGGACGAGATCACCGCCGTCCTGCACCACCCCGACGGCCTGCTGTGGCGCACGGCCCCGGAGACCACCGAGGAGCTCTGGCACCCGATACGGGCGCTGCTGCGCTAGCGGCGCCCCGCCCGTGGCGCGCGGCCCCGGCTAGACCACGGGCTTGCCCGACAGGCCGACGCCCGCCGTCCGCATCTCCTCAAGCGCCAGCGAGGTGGTGCGCTCGGCGACCCCGGCCGTGAGGTCGAGCAGGACGGTGGTGACGAAACCGGCCCGCACCGCGTCCAGGGCGGTGGCCCGCACACAGTGGTCGGTGGCGATGCCCACCACGTCGACCTCGGCCACCTGCCGCGCCCGCAGCCACTCCGCCAGCGCGACCCCGTTCTCGTCGAACCCCTCGAAGCCGCTGTACGCGGCCGCGTGGGCGCCCTTGTCGAAGACGGCGTCGACGGCCCCGCAGGCCACCGCGGGAGCGAAGTTGGGGTGGAAGCCCACGCCCTCGGTGCCGGCCACGCAGTGCGGCGGCCAGGAGTGCTCGAAGTCGGGCGTGGCCGAGAAGTGCGTACCGGGGTCGATGTGGTGGTCGCGGGTGGCCACCACATGGCGGTAGGCGGACCCGGCCGCCTGGCCCACGAGGTCGGTGATCGCGGCGGCGACGTCCGCACCGCCCGCGACCGCGAGGGAGCCGCCCTCACAGAAGTCGTTCTGGACGTCCACGACGATCAAGGCGCGGTGCATGTCGGCTGTCCTTCGGTCTACGGGCCCGGGACCGGGCTGTTCCTTGAGCGTAGAGACTTCGTCCGGCGCACGGCAGGGGGCAAACGGGGGCGGAAATCCCACCGCCGGCCTCAGACGTACTCGGTCGGGATGACCGGCTCGCCGCGCGAGAGCTGGCCCGCGGACATCGGCAGCGCGGCCAGCGCGTCGATGTGCCGCGCGCGGGCGGCGTCCAGCGGCTCGCGGGCCACCACCGTGCCGCCCTTGACCAGCTCCACCAAAAGCTGGCGCTCGACGAGCTCGGCCGGCACCGCGCCGGTGCCGATGACCTCGGCCTCGGCGATGCCGTACGCGTCCGAGCGGCGCGCGGCCCACTTGCGGCCGCCCACCGAGGACTTCGCGCCCAGCGACTTCTTGGCGACCGAGATCAGGGGCGCCTTCGGGTCGGCGGACTGCGCGCGGGCGACCAGCTTGTAGACCATGGAGCAGGTCGGGTGCCCGGAACCCGTGACGAGCTGGGTGCCCACCCCGTAGGCGTCCACCGGGGCCGCGGCCAGCGAGGCGATGGCGTACTCGTCGAGGTCGGAGGTGACCACGATCTTGGTGGCGGTCGCGCCGAGGTCGTCCAGCTGCTGGCGCACCCGGTGGGCCACCAGGAGCAGGTCGCCGGAGTCGATGCGGACCGCGCCGAGCTCGGGCCCGGCGATCTCCACGGCGGTGCGCACCGCCTCGGCCACGTCGTACGTGTCGACCAGCAGGGTCGTGCCGCGGCCCAGCGAGTCGACCTGGGCCCGGAAGGCGTCCCGCTCGCTGTCGTGGAGCAGGGTGAAGGCGTGCGCGCTGGTGCCGACGGTGGGGATGCCGTAGCGGAAGCCGGCCGCCAGGTCCGAGGTGGAGCTGAAGCCGCCGACGTAGGCGGCGCGCGAGGAGGCGACCGCGGACAGCTCGTGCGTGCGGCGCGCGCCCATCTCGATCAGCGGGCGCCCGCCGGCCGCCGTCGACATCCGGGAGGCGGCGGCCGCGATCGCGGAGTCGTGGTTGAGGATCGAGAGGATCACGGTCTCCAGGAGCACGCACTCGGCGAAGGACCCCTCGACGCGCAGGATCGGCGAGCCCGGGAAGTAGACCTCGCCCTCGGGGTAGCCCCAGATGTCGCCGCTGAAGCGGTAGGAGGAGAGCCAGCGCAGGGTCGGCTCGTCCACGATGGAGTGGTCGTGCAGGAACCCGAGCACGCCCGCGTCGAAGCGGAAGTTCTCGACCGCGTCCAGGACGCGCCCGATGCCGCCGACCACGCCGTAGCGGCGGCCCTCGGGCAGGCGGCGGGTGAAGGCCTCGAAGACCGAGCGCCGCCCGGCCGTGCCGGCCTTGAGGGCGGCCTGGACCATCGTGAACTCGTACTGGTCGGTGAAGAGCGCGGTCGACGGCACGTCCACCGGCAGCCCAAGGTCCGCAGCATTCACAGCGAGCTACCTCGCACTTTCGTCCGGGCCGGGCGCACGCCGGCCGGGGATCGGGGCACCGGCCCCGGGAGCGGGGGCCTGTGGGGGATGCTACCCCGAATACTCGTCACTTTGACGATTTCTAGGGGCCCGTTTGTGCGATGACCCGCCGCGGGTGGCAGCATGGAGGCCGTGGCTGTGATTCCCGGGGGCCACCCCCCGGACCCCCGGCAGTGAAAGACAGGTCGCCCAGAGCCGTGAGTGTCGCCCCCGTAGAGATCGAACGCCCCGAGTCGGCGGAGTCGAGCCGGCCCGTCGCCGAACCCGATGTGCCCTGGGTGACGCTCGTGCACAACGACCCGGTCAATTTGATGAGTTACGTGCAGTACGTCTTCCAGTCCTACTTCGGCTACTCGAAGGACAAGGCCCACAAGCTGATGCTCGACGTGCACCACAAGGGACGGGCCGTGGTCTCCAGCGGCAGCCGCGAAGAGATGGAACGCGATGTGCAGGCGATGCACGGCTACGGCCTGTGGGCGACGCTGACGCAGGACCGCGGCTGA

Protein sequences of DBSCAN-SWA_2

>CP032698|5286774:5353693|5309925_5311224_+|AYG82570.1|DBSCAN-SWA
MKLSARTALPLAALALAGLAACAPGTSDNGAKSDDKSGTLRVWLFQEVNNGPKQHVVDRAVAAFEKSHQGAQVQVEYIPVESRAQKIKAAFNDPGSAPDLIEYGNTDTAGYVKDGGLAEVSAEFVAWDEAKDTDPTAKQSVTVGGKIYGAPLFVGVRALYYRTDVLKELGLAVPRTQDELIATAKKIHQSKPDLYGLVVGGAYTYGALPFLWANGGELATENGGKYTSALDAEPARKGITAYTSLFGDDNCPAAKCAQMGGNATVTAFAGGKAAMAIGGDFNHAAVDAGAVKGKYAVVPLPGRAPGSIAPAFAGGNNIGVLKSSSHRTLAVGLMEQLAGKATQRELFDAMGFLPTYTDVRADVAKKQPFVEPFVRTLAAGAKFVPASPGWGRIDSSLVLPTMFQEIVSGKKDVAKASSDAAKRMNDVFGAAG
>CP032698|5286774:5353693|5338756_5340400_-|AYG82593.1|DBSCAN-SWA
MEIAKTEQDADAARRAAWLSASAAARRTSPRSGPPKALKRAVRVALAAGVLIGGVVLIMPDDPGPKAPPPAPGPAARALTAVTGGAPASVADVTALITDRAAWVRTHPKDEASWAVLGSAYLERGVRGADSSFYPRAEWALRRSLEVRPKDNLDAEIGLAALANARHDYAAARTLAESVRARKADRWTLYPPLIEAYNGLGDAKGAAKAVERLLELRDGSAALTQAAEVYRAHGWREDASVALDEAVAHATSPVQKAASLVAAGDLAWERGEPEAALARYEAALRTDPGAHAALAGRARAGAALGKKADAQRDYLAAVAVLPRPEYLLELGELYESQGLDGDARTWFDKLQELAARDGSNGVDDALVLGRYEADHGSAHAAVDRLEAEWKAHPSPAVEDALGWAMYRAGESEEGLTHAKKATDSGVRSALFSYHQAVIERELGQSGAARRHLQDALRTNPYFSPVLAPKAKEALTALGEPPEGGPRDMYGHVAAAASGSGSGSGSGSGGESSASSDASSNQSGQSSQGARRPAKPRPAKPAKPSQRR
>CP032698|5286774:5353693|5326812_5328639_+|AYG82581.1|DBSCAN-SWA
MPVIPYTESPEPETVTTTASHHLSPAFPGRAPWGTANKLRAWQQGALERYVQEQPRDFLAVATPGAGKTTFALTLASWLLHHHVVQQITVVAPTEHLKKQWADAAARVGIKLDPDYSAGPLSREYHGVAVTYAGVGVRPMLHRNRCEQRKTLVILDEIHHAGDSKSWGEACLEAFDPATRRLALTGTPFRSDTNPIPFVTYEEGNDGIRRSSADYTYGYGNALADGVVRPVIFMSYSGNMRWRTKAGDEIAARLGEPMTKDAISQAWRTALDPRGDWMPNVLRAADQRLTEVRKAIPDAGALVIASDQDSARAYAKLIREITGSKATVVLSDDTGASKRIDEFAEGDDRWMVAVRMVSEGVDVPRLAVGVYATTISTPLFFAQAVGRFVRSRRRGETASVFLPTIPMLLGFANEMEVERDHVLDKPKKDGEEEDPYAESEQEMDEANREQDEDTGDDMLPFEALESDAVFDRVMYNGAEFGMQAHPGSEEEQDYLGIPGLLEPDQVQMLLQKRQARQIAHSRQKPAEQADLLEMPAERRPVVSHKELLELRKSLNTMVGAYVHQSGKPHGVIHTELRRVCGGPPSAEATAGQLRERIKKVQEWATRMK
>CP032698|5286774:5353693|5336212_5336860_-|AYG82590.1|holin|DBSCAN-SWA
MGFWDYLSSRHQQLLTDALQHASAVFQCMVIATVLGILIGVVTYRSGWAAALAITSTSTVLTIPSLAMIGLLIPLVGLGVAPTVVTLTLYGLLPIVRNAIVGLRGVDPSLVDAAKGIGMSRPARLLRVELPLAWPPILTGIRVSTQMLMGIAAIAAYASGPGLGNEIFRGIASLGSANAINQVLAGTLGIVVLALLFDAAYVLIGRLTIPRGIRV
>CP032698|5286774:5353693|5297745_5298924_+|AYG82559.1|DBSCAN-SWA
MSAEPEVAAPHGPHGPGGPLDGFTVGVTAARRADELATLLTRRGAAVLHAPALRIVPLADDSELLAATRELITKAPDTVVATTAIGFRGWVEAADGWGIGDALLKTLKGVELLARGPKVKGAVRAAGLTERWSPSSESMAEVLDRLLAEGVAGRRIAIQLHGEPLPGFVEALRAGGAEIVGVPVYRWLPPQDPAPLDRLLDATVSRGLDALTFTSAPAAASLLNRAEERGMLAELLLALRDDVLTACVGPVTALPLQARGVHTLAPERFRLGPLVQLLCAELPSRARVLPLAGRRVEIRGHAVLVDGALRPVPPAGMALLRTLARRPGWVVSRAELLRALPGSGTDEHAVETAMARLRTALGAPRVIQTVVKRGYRLALDPAADAKYADDAD
>CP032698|5286774:5353693|5351124_5351712_-|AYG82602.1|DBSCAN-SWA
MHRALIVVDVQNDFCEGGSLAVAGGADVAAAITDLVGQAAGSAYRHVVATRDHHIDPGTHFSATPDFEHSWPPHCVAGTEGVGFHPNFAPAVACGAVDAVFDKGAHAAAYSGFEGFDENGVALAEWLRARQVAEVDVVGIATDHCVRATALDAVRAGFVTTVLLDLTAGVAERTTSLALEEMRTAGVGLSGKPVV
>CP032698|5286774:5353693|5350794_5351094_+|AYG82601.1|DBSCAN-SWA
MPGGGYCKLPGGSVVVALTLPNPAAPGSDVRVLVHAVNRARALTRLRNLGLRAVYLRGQTEPPTLDEITAVLHHPDGLLWRTAPETTEELWHPIRALLR
>CP032698|5286774:5353693|5289241_5290480_-|AYG82553.1|DBSCAN-SWA
MPHPTPLARPRNPYLRLFATPGARAFTLGNLVARLPMGMFGVSAVIMIAGARGSYALAGAVTATGLAATALVAPWTARLVDRYGQARTAVPTTAIAVCGSLALLLCVRLDAPDWTLFAAYAATATTPNTGGMSRARWAHLHGGPSAADAAALHTANSFEQAADELCFMLGPVAAAFLCSALFPEAGTLVGAVLLMTGVLIFAAQHATEPPATPRAPAAKSPVRARGFAPLLAVFLATGAVFGSLEVVTIAYADALGHRAAAGAVLALQAAGSCVAGLLYGSARPARDTARRLVGCLAAMTALMWLPLLAARAIGSLFALGGALLLAGAATAPTMVTGMTLVQRRTPQGQLNEGMTLAVTAILGGIAAGSALGGQVIEHAGPETGYVVPLCAAATALLLGAAGRGRYGAPARR
>CP032698|5286774:5353693|5292853_5295007_+|AYG82556.1|DBSCAN-SWA
MTTTQAKPRPTRRKRLPMRYLLPLLLLVALVAMLMLRGYVHSEISADHRVRDPAPTDRVPESIIDGGPVIDARTPGKPVSLQIPDHRIVLTFDDGPDPTWTPKVLDELKKHHAHAVFFVTGTNASRYPDLIKRMVAEGHEVGLHTFNHPDLSYQSKARIDRELSENQLALAGAAGVHSSLFRPPYSSFADAMDNDTWPVVQYVGSKGYVVALDSTDSEDWQRPGVKKIIHNATPEDDKGAIVLMHDFGGDRSQTVAALDQFLPDMQESGYTFVNLTTALGAPSALTPVSGMDLWKGQAFVGAVQVAEHTTDFLVVGLAVIGVLVFTRFGLMLVLSFAHARKVRRKDFSWGPPVTEPVSVLVPAYNERECIANTVRSLMASDHPIEVIVIDDGSSDGTADIVEALGLPNVRVVRQENAGKPAALNNGIAHARYELVVMMDGDTVFEPGTVRELVQPFGSSRVGAVAGNAKVGNRNSLIGAWQHIEYVMGFNLDRRMYDLMGIMPTIPGAVGAFRRQALERVGGMSEDTLAEDTDITMAIHRDGWRVVYAENARAWTEAPESVQQLWSQRYRWSYGTMQAIWKHRGAIKDRGASGRFGRVGLPLVALFMVVAPLLAPLIDIFLLYGIVFGKSQQTVLAWLGVLLIQAVCAAYAFRLDKERLTHLLSLPLQQVLYRQLMYVVLLQSWITAVTGGRLRWQKLRRTGVVEAPGNPAERKAAG
>CP032698|5286774:5353693|5301750_5304162_+|AYG82564.1|DBSCAN-SWA
MAAQDAAVDTASGTAESTVDSVREREIAGEQVHLDQVYRRLEEKIHEAEFLMNDAAKRGQVGTPGALAERDAQVFRAGVHLNRLNNEFEDFLFGRIDLLLGQDGKKGPDGAYTSIDPAEDAVRPDGTADIAETLHIGRIGVLDSDYSPLVIDWRAPAAAPFYRSTPVDPGRVVRRRVIRSKGRKVLGVEDDLMRPELRATLNGAELPVIGDGALMAALGQARSHTMRDIVASIQAEQDMVIRAPAASVTYVEGGPGTGKTAVALHRAAYLLYQDRRRYSGGILIVSPTPLLVSYTEGVLPSLGEEGQVAIRAVGNLVDGAEATEYDDPAIARIKGSSRMLHVLRRAARGALEGPGEQQSRRSRRRGGEQLALGEQAPQPHPAQRLRVVAFGARIELEGEELRRIRQTVLGGTAPVNLLRPRARRLLLDALWSKSAAAGRAGDVSRGDPELAAELRSSFDDDITSEDAFIAFLDAWWPELTPRGVLAAMADEKRLGRWARRVLNQGEVRRLARSLARAADGAFSVHDVALLDELETLLGAPARPKRKREYDPLDALTGLEELMPHREETQRERAERLALERTEYAHVIVDEAQDLTPMQWRMVGRRGRTATWTVVGDPAQSSWSDPDEAAEARDEALGSRPRRRFELTVNYRNPAEIAELAARVLALAMPGMKSPAAVRSTGVEPRFAVVRDGDLARTVREEAARLLDRVDGTVGVVVAMRRREQAARWLAELGDRVVALGSLEAKGLEYDATVVVSPAEIADESPAGLRVLYVALTRATQQLTVVSGDRDEPDAAGVPDLLRE
>CP032698|5286774:5353693|5304580_5306014_+|AYG82565.1|DBSCAN-SWA
MATAPSVSYSMTVRLEVPASGTAVSQLTTAVESSGGSVTGLDVTASGHEKLRIDVTIAATSTSHADEIVEELRGIEGVSLGKVSDRTFLMHLGGKIEMQSKHPIRNRDDLSMIYTPGVARVCMAIAENPEDARRLTIKRNTVAVVTDGSAVLGLGNIGPMAAMPVMEGKAALFKRFADIDAWPLCLDTQDTDEIVAIVKAIAPGFAGINLEDISAPRCFEIEARLREALDIPVFHDDQHGTAIVVLASLTNALRVVGKGMGDVRVVMSGAGAAGTAILKLLLAAGVKNAVVADIHGVVHAGREDLVDASPESALRWIADNTNPEGLTGTLKEAVVGADVFIGVSAPNVLNGDDVAAMAEGAIVFALANPDPEVDPAIARETAAVVATGRSDFPNQINNVLVFPGVFRGLLDAQSRTVNTDMMLAAAGALADVVAEDELNANYIIPSVFNDKVAGAVAGAVRTAAKAAGAAVTGPTSA
>CP032698|5286774:5353693|5299623_5300184_+|AYG82561.1|DBSCAN-SWA
MVRFDSGRICLDLVATGARESEQLGRVEELSRWLLAAGLVPRDTPLAGIDDDWLARFLELRRCVSQLIHAELGGPADAAPAALDRVNALAAAAPPGVRAVRGADGGLVRTLSRAPECGALLAVVARDAVDLLTDPEARSRLRQCEGDSCRLLYLDTSRGRRRRWCSSEACGNRERVARHRRRLAAL
>CP032698|5286774:5353693|5316494_5318549_+|AYG82575.1|DBSCAN-SWA
MTDRNNEHEPERGHENDYGRGRENEYEYGYGRGPESENENEYGQPHQYGYGQAPRHGAWEPVPHGGEYEPDATAFVQLPPDMDMMGAPLAAPGHGYVPPMIVPLTPLAATDPGATGIWRIPTEPAEPAESSEPGDQGAPGASGAHPAPGAQTVVWPEPPAPTPLPASSAQPAHDPSATAQWHFPDEPSLAGTGQWTIPVAEGELPEESGEFTTSALIEQWGSTPPATLPGGAPAPWAHQFPEPPQEPLPDPAQEPLPVPSPEAHAPTPGHAPLAADHPANALDVHHDVRPDVHHDVHPHEAPDAPLAPDASEVPVLPGALEAPSAAHAPVVPDVHDVAEAGAMPAPASVPESRPHPQPHPASEPRPESPAAPTAPESLPEELVAVEPLAEAVPESHGMSEAAVLAELAELAGAPEAELAPGTGTGTGAETAALPGTPEPTDAPDATGTTDTPAPSGASGTDRGTDLAIDLGTDPGDATPDAEPTPAVTIAPDLEHPRASYVLRVNGADRPVTEAWVGESLLYVLRERLGLAGAKDGCSQGECGACNVQVDGRLVASCLVPAATAAGSEVRTVEGLATDGEPSDVQRALAECGAVQCGFCIPGMAMTVHDLLEGNHAPTELETRQALCGNLCRCSGYRGVLDAVKDVVAGREAAGALAEEARIPHQAPPGAGSAMPPHTHDGGMA
>CP032698|5286774:5353693|5308770_5309331_+|AYG82568.1|DBSCAN-SWA
MTEVSSLTGRLLVATPALADPNFDRAVVLLLDHDEEGTLGVVLNRPTPVGVGDILESWAGLAGEPGVVFQGGPVSLDSALGVAVIPGDEGPLGWRRVYGAIGLVDLEAPPELLAAALGSLRIFAGYAGWGPGQLEDELTDGAWYVVESEPGDVSSPEPESLWRAVLRRQRSELAMVATYPDDPSLN
>CP032698|5286774:5353693|5311220_5312180_+|AYG82571.1|DBSCAN-SWA
MSPATAERATAPAPPTGLAPGRARGRPVRRAGWTPWLYLAPALAVLGALLVYPIYQLGLISFLEYTQAQVSGGEPTSFQGFGNYAELFSDSQFWSVLLATLVFAAACVLSTLAVGCALAVLLTRVRALPRLTLMLAALGAWATPAITGSTVWLFLFDPDFGPVNRVLGLGDHSWTYGRYSAFLLVLLEVVWCSFPFVMVTVYAGIRAIPGEVLEAAALDGASQWRIWRSVMVPMLRPILTVVTIQSVIWDFKVFTQIYVMTNGGGIAGQNLVLNVYAYQKAFASSQYSLGSAIGVVMLLILLAATLVYLRLLRRQGEEL
>CP032698|5286774:5353693|5312176_5313031_+|AYG82572.1|DBSCAN-SWA
MRSLTALFAVRIRRPGRLIAEGAALLVAAVVAFPLYWMALSAFKPAGEVQSSHPRPWTLAPSLDSFRRVFSQQDFGRYFLNSLIVAGSVVLLSALIAFLAATAVTRFRFRFRTTLLIMFLVAQMVPVEALTIPLFFLMRDLGQLNTLGSLILPHLAFSLPFAIWMLRGFVKGVPVALEEAAALDGASRTRFLWQILFPLVFPGLVATSVFSFISAWNDFLFARSFIISDTSQSTLPMALLVFFKPDENDWGGIMAASTVMTVPVLVFFVLVQRRLVSGFGGALK
>CP032698|5286774:5353693|5300311_5300875_+|AYG82562.1|DBSCAN-SWA
MRKDAAVADDRPRGAKHRSVPDEELMRALYREHAGPLLGYVMRLVAGDRQRAEDVVQETLIRAWKNAGQLNRATGSVRPWLVTVARRIVIDGHRSRQARPQEVDPSPLEVMPAEDEIDKALWLMTLSDALDDLTPAHREALVETYFKGRTVNEAAQALGVPSGTVRSRVFYALRSMKLALEERGVTT
>CP032698|5286774:5353693|5290582_5291593_+|AYG82554.1|DBSCAN-SWA
MPHDTDPRLLRAFAAVAEELHFTRAAARLFVAQQALSRDIRRLERELGAELFVRTTRAVTLTADGTRLLPYARRVLAAHDEFRDAWAARGAERPLLVDVSAPVGTGARVLAEARAQAPGVEFVARFISGLTGAAADILAGRLDVSFGRVAGLDPAVLAGLAHQPVRYERMAVLLDAGHRLAGLAEVPLDALAGETLYVAAGNRATAEWTDLAERLFAGRGIEAAAPFPEIAGEEEFVRVVRKRGWSVLASTEFMDVPGMVVRPLTGPVPLAPVSLVWRDGLTHPGLDVLRRVAREQAAAHGWLERPAGSWLPEPDMSLMVVNAPRVGRIRRSSRDT
>CP032698|5286774:5353693|5351822_5353151_-|AYG82603.1|DBSCAN-SWA
MNAADLGLPVDVPSTALFTDQYEFTMVQAALKAGTAGRRSVFEAFTRRLPEGRRYGVVGGIGRVLDAVENFRFDAGVLGFLHDHSIVDEPTLRWLSSYRFSGDIWGYPEGEVYFPGSPILRVEGSFAECVLLETVILSILNHDSAIAAAASRMSTAAGGRPLIEMGARRTHELSAVASSRAAYVGGFSSTSDLAAGFRYGIPTVGTSAHAFTLLHDSERDAFRAQVDSLGRGTTLLVDTYDVAEAVRTAVEIAGPELGAVRIDSGDLLLVAHRVRQQLDDLGATATKIVVTSDLDEYAIASLAAAPVDAYGVGTQLVTGSGHPTCSMVYKLVARAQSADPKAPLISVAKKSLGAKSSVGGRKWAARRSDAYGIAEAEVIGTGAVPAELVERQLLVELVKGGTVVAREPLDAARARHIDALAALPMSAGQLSRGEPVIPTEYV
>CP032698|5286774:5353693|5323837_5324368_+|AYG82579.1|DBSCAN-SWA
MSVLTAVWAMAGCSADSPVPSLPKSLCWGAFAGSAVAPIVPTGDATTVENNRPFDVFAPTDQTTYCTVRVDNDARFIAWAELRRSGKGTDWNHSARHLGTRIEAGDEAFVWGGDAAAVFECGRPDVARGPTLPASAKYIELQLTADRAPETQRTRDVLTTLMRQYVHFAKQRLKCR
>CP032698|5286774:5353693|5353387_5353693_+|AYG82604.1|protease|DBSCAN-SWA
MSVAPVEIERPESAESSRPVAEPDVPWVTLVHNDPVNLMSYVQYVFQSYFGYSKDKAHKLMLDVHHKGRAVVSSGSREEMERDVQAMHGYGLWATLTQDRG
>CP032698|5286774:5353693|5343294_5344473_-|AYG82596.1|DBSCAN-SWA
MSVGLGPTGRGERAALSSAALSSAAPVARRAWSAVGAFAAIRALGLLALVLWSRANDKDAHALLSARWDSLWYVRVVESGYDFTLTAPDGRVLSDLAFFPLLPWLEQALAAVTPLGPGDAGLLVSAVAGPLAAWALYLTGRHLHGHRAGLLLAAVWAAVPVGIVQSMAYSEALFTALAAWALYAVLRRRWVEAGLLASLAGLTRPVGLAVAAALWAGAVVEARRTRRVDARLLTGAVLAPLGAAGYVLWVGARRGSVFGYLHVQAEWGNGFDGGLAYGKFIVDHLGGWPVVLAGLGMIAGTALALWAYGACVRGGQPLPLLVYTGIVMALALCSSGYFGSKPRLLLPAFPLLLPVAVALSRMRGVGAVGVVGALSVASAVYGATWLNGSGPP
>CP032698|5286774:5353693|5306413_5306695_+|AYG82566.1|DBSCAN-SWA
MNRSELVAALADRAEVTRKDADAVLAALAETVGEIVAKGDEKVTIPGFLTFERTHRAARTARNPQTGDPINIPAGYSVKVSAGSKLKEAAKGK
>CP032698|5286774:5353693|5315631_5316498_+|AYG82574.1|DBSCAN-SWA
MTLPASLDEAVAALAAMPAAVPVAGGTDLMAAVNRGLLRPAGLVGLGRINEIRGWQYQDGHALLGAGLTHARMGRPDFAALIPALAAAARAAGPPQIRNAGTLGGNIASNAPTGDALPVLAALEATLVIAGPDAARREIPVSHLLAGRDMLAPAELIGYVRVPLLHAPQVFLKATGRTGPGRATASVAVVLDPARRGVRCAVGAIAPMPLRPLEAERWIASLIDWDGERAALAPEALGAFGEYVAAACIPDPAPPADGSPPPPLSPAVLHLRRTVAALARRALGRALS
>CP032698|5286774:5353693|5298856_5299405_-|AYG82560.1|DBSCAN-SWA
MNTHDNMRVGGGSWALGAATVATGLAAGSFFVFSCAVMPALARSDDHTYVAVMRNINDVIQNPVFFASFLGAPVLIAVAAWQQRHEPGVRGSTYAALGAYALAFVLTSAVNVPLNDALARATDPAAARAHFEGPWVAWNAVRAGLCTLSLGFLARACLGRLSPRRPRISRRRPGRVPVGSRA
>CP032698|5286774:5353693|5342053_5342542_-|AYG82595.1|DBSCAN-SWA
MQTVVERELELKLVLSPERSIPVPARLTYRTDDPYAVHITFHVGSETPVHWTFARELLVEGVFRPCGHGDVRIWPTKVEGRNVVLMALSSPDGDALLEAPSAQVSAWLERTLRAVPPGSETERLGIDDGLAELLAPATGRGTDELWLRDPWPSDESRPEDGA
>CP032698|5286774:5353693|5313599_5315264_+|AYG82573.1|DBSCAN-SWA
MDIDHLIPAPTRTHPTHPTPTHLTPTTTLHTTPETSPLAPLLRGTIGVATGLPLADGGVGAERVVLRVRAEIGGRHGPEAYRLSTDRSHEDATVLIEGGTPAGVFRGIQTLRQLLGPDAFRRAPVEPGRRRRRWALPQVTVEDHPRFAWRGLMLDVARHFMPKDGVLRYLDLIAAHKLNVFHFHLTDDQGWRIEIKRYPRLTEVGAWRGRTKWGHRASPLWDEKPHGGYYTQDDIREIVAYAAERHIRVVPEIDLPGHSQAAIAAYPELGNTDVIDTASLSVWDTWGVNPNVLAPTDTTLRFYEGVLEEVLDLFPEDVSPFIHIGGDECPKEQWQKSDVAQERIRELGLAGENELQSWVIRHFDTWLSARGRRLIGWDEILEGGLAPGAAVSSWRGYGAGIAAAEAGHDVVMCPEQYVYLDHRQAAGADEPVPIGFVRTLEDVYRFEPVPPQLDPEAAAHILGTQANVWTEVMENQSRVDYQVFPRLAAFAEVAWSALPAPADRDFADFERRMTVHYKRLDALGVDYRPPTGPLPWQQRPSVLGRPIEGAPPNR
>CP032698|5286774:5353693|5332286_5332913_-|AYG82586.1|DBSCAN-SWA
MPENKRSAAPPPENPAGERILDARSLRGLAHPLRIRILKSLRHDGPATASQLGDRLGESSGATSYHLRQLATHGFVEDDPARGKGRERWWKAVHNGTSFADDLHTSSDPEVRGAANLFLHEIAGIHTQELSTWLATMHDWPEPWSTSGDLSDFTLNLSPAQLHELNEKLHAVVESYRTLSPGPGAPSDAEAAQVRVHLHSFPRGNPSR
>CP032698|5286774:5353693|5296304_5297642_+|AYG82558.1|DBSCAN-SWA
MTGRWIDRWEPEDDTFWRETGRRVARRNLFLSVFCEHVGFSIWSLWSVMVLFMGPAYGVDPAGKFFLISVATLVGALVRIPYTFAVARFGGRNWSVFSALLLLVPAGAAWFAMEPGTSYSTFLLVSALAGVGGGNFASSMTNINAFFPLREKGWALGLNAGGGNIGVPVVQLVGLLVIATAGATHPRIVLAVYLPLIALAGLGAALGMDNLAPVRNDTGAVGEALREAHTWIMAFLYVGTFGSFIGYSFAFGLVLQTQFGRTPLQAASLTFIGPLLGSLIRPVGGRLADRHGGARITLVNFAAMAVATCVVLYASAQKSLPVFLTGFIALFALGGLGNGSTFKMIPGIFQAKALARGLAPQAAAAYGRRLSGAAMGLVGAIGALGGLAINLAFRQSFGTTGTGTTAYAAFLACYAACFTVTWAVYIRRPAEAGVPATAPPAAVEV
>CP032698|5286774:5353693|5329128_5329773_+|AYG82582.1|DBSCAN-SWA
MTAETSQTLDRGLRVLKLLADTDHGLTVTELSTKLGVNRTVVYRLLATLEQHALVRRDLGGRARVGLGVLRLGRQVHPLVREAALPALRSLAEDIGATAHLTLVDGSDALAVAVVEPTWTDYHVAYRAGFRHPLDKGAAGRAILSARQAGALAEPGFTLTHGELEAGASGAAAPLVGVTGIEGSVGVVMLADAVPERVGPRVVDAAKEVADALR
>CP032698|5286774:5353693|5300871_5301633_+|AYG82563.1|DBSCAN-SWA
MTSGEYAQGSPHEAVGAYVLGVLDDAEATAFEAHLAGCEPCAAELDALAGMEPMLAGLKEFPGPAAQPLRPAPPDLSMALINEVAAQRARRRRRTTYLVAAAAALIVGGPAVAVVATSSGTGTHQSAEAHPTSPAEDAFFNHMTQKTSATDPTSEVTATVGTEPKAWGTHTVLELKNVKGPLKCSLIAIGKNGERETVTSWAVPNWGYGIKDSPHESARYPLYVHGGTAMTHDQIDHFEVRTFDGKALVDIPA
>CP032698|5286774:5353693|5309387_5309681_+|AYG82569.1|DBSCAN-SWA
MSTLEPERGAGTGTLVEPTPQVSNGDGDHERFAHYVQKDKIMASALDGTPVVALCGKVWVPGRDPKKYPVCPMCKEIYESMGAGGDKDKDKGGKDKK
>CP032698|5286774:5353693|5332056_5332233_-|AYG82585.1|DBSCAN-SWA
MHSDIHLQMHHQRATELAAEARATLPRERHLRAQLGWLLVELGLRLTQQAPRHRARLA
>CP032698|5286774:5353693|5337492_5338638_+|AYG82592.1|DBSCAN-SWA
MTETIDHTPETARQADPFPVKGMDAVVFAVGNAKQAAHYYSTAFGMKLVAYSGPENGSRETASYVLTSGAARFVFTSVIKATSERGRFLAEHVAEHGDGVVDLAIEVPDARAAYKYATEHGATGLQEPHEVSDEHGTVVLAAIATYGKTRHTLVERSGYEGPYLPGFVTAAPMVEPVEKRFFQAIDHCVGNVELGKMNDWVAFYNNVMGFTNMKEFVGDDIATEYSALMSKVVADGTLKVKFPLNEPAIAKKKSQIDEYLEFYGGPGVQHIALATNDIVASVRAMRAAGVQFLDTPDSYYDTLGEWAGETRVPVETLRELKILVDRDEDGYLLQIFTKPVQDRPTVFFEMIERHGSMGFGKGNFKALFEAIEREQELRGNL
>CP032698|5286774:5353693|5307175_5308516_-|AYG82567.1|DBSCAN-SWA
MTGTDDVLLVHGGTPLEGEIRVRGAKNLVPKAMVAALLGSGPSRLRNVPDIRDVRVVRGLLQLHGVTVRPGDEPGELILDPSHVESANVADIDAHAGSSRIPILLCGPLLHRLGHAFIPGLGGCDIGGRPIDFHFEVLRQFGATIEKRADGQYLEAPQRLRGCKITLPYPSVGATEQVLLTAVLAEGVTELSNAAVEPEIEDLICVLQKMGAIIAMDTDRTIRVTGVDTLGGYTHRALSDRLEAASWASAALATEGNIYVRGAQQRSMMTFLNTYRKVGGAFEIDDEGIRFWHPGGSLKSIALETDVHPGFQTDWQQPLVVALTQATGLSIVHETVYESRLGFTSALNQMGAHIQLYRECLGGSDCRFGQRNFLHSAVVSGPTKLQGADLVIPDLRGGFSYLIAALAAQGTSRVHGIDLINRGYENFMEKLESLGAKVELPNGSLV
>CP032698|5286774:5353693|5347453_5347825_-|AYG82599.1|DBSCAN-SWA
MPRPTAAQLSYGSATVVFSTVAMLLLSRTESGVGVAVIVLAALLLGLLVAVTVPMPLARRTRADAHANADGRTVPAAGAAPVNRAAVVETSAAGAAASPSGQWGSVPAPRERRASTRQHSLRS
>CP032698|5286774:5353693|5334034_5334913_-|AYG82588.1|holin|DBSCAN-SWA
MTPRSPAPAERPPGEHEVGGHAFRDELPGPLDEPEPEHETGPAPDRPARRITWRKLAFLPVVLAVVLVITYLWITHVHLDTIAKNSLNNGNVQLRLWQHVKLTAISTFWVLLIAIPLGIALTRRGVSRAAPLVTAIANIGQATPAIGLLALLVIWLGIGPGTAIVGMVIYAVLPVLSNTVAGLRAIDPQLVEAARGIGMSAPGTLGKVELPLAVPLILAGVRTALVLNVGTATLATFGGGGGLGDLITSGIQTQRMPVLVLGSILTVALALLVDWLASLAEIALTPRGLEVE
>CP032698|5286774:5353693|5330001_5330790_+|AYG82583.1|protease|DBSCAN-SWA
MLTRHSRLRNLAIGAAPVVALLAVACFAPLPFAVAQPGPTANVLGNDEGKPVITISGAPTRPTSGQLRMTTIVATGPTADVGIGDVVDGWFRTDRAVMPRGSVYPGGGSEKEISAHNQAQMKQSQDAASVAALGYLGLSPDKVKVELHLADVGGPSAGLLFTLGIIDKLNGDGSGGDLTGGRTIAGTGTITGGGDVGAVGGVALKTQAAARDGATVFLVPKGECSDAESELPKGLRLIPVTTLKGAVSALQALRKGDPVPSC
>CP032698|5286774:5353693|5321088_5321481_+|AYG82577.1|DBSCAN-SWA
MASGAAAGTQGTRGVEGAPGADGGDLVAHADDLGLIGSDAYKLYDGFRRDGDHARAATFEAARALSADNFTSGAALMRLHDTWQSQYTTLRDACAQISNHLDHSTAQHAKDDARVRGSLTAVSVLSDYIN
>CP032698|5286774:5353693|5336885_5337371_-|AYG82591.1|DBSCAN-SWA
MAIDHLDGRLIVLLAREPRIGVLEASRRLGVARGTVQARLDRLQSNGVIRGFGPDVDPAALGYPVTAFATLEIKQGQGADVRAHLASVPEVLELHTTTGHGDMLCRLVARSNADLQRVIDRVVGFDGIVRASTAIVMENPVPLRIIPLVEQAGQDSVPGGG
>CP032698|5286774:5353693|5333051_5334035_-|AYG82587.1|DBSCAN-SWA
MRHPRTALLAASGSLALLAVVSGCGLKSGSPLVDDVLPGSIGKGLPLKGASLTVTSKNFSENIVLGQMVGLVFKAAGAEVLDRTNLPGSISAREAIAKGDADAMYDYTGTAWITYLGNSKPITDPGAQWRAVRDADLKNGVTWLPQSTLNNTYSLGISQANNAKYHLKTLSDVAALAKKDPSAVTICVENEFASREDGLPGMEKAYGMTVPASNIQKMDAGIIYTQVSKSNSCLLGEVFTTDGRIQAMNLATVQDDKHFFPNYNAAPVVHSRTYEKYPAIAALLDPLSAKLTTGIARQLNAKVDVDGQDPHDVALEWLVREGFIRKG
>CP032698|5286774:5353693|5288008_5288536_+|AYG82552.1|DBSCAN-SWA
MAKNTGKDKEKDSKRKLVAQNKKARHDYLIIDTYECGLVLTGTEVKSLRQGRASLVDGFVQIDGGEAWLHNVHVPEYAQGTWTNHSARRKRKLLLHRMEINKLESKSSESGHTIVPLALYFKDGRAKIEIALAKGKKEYDKRQTLREKQDRRETDRAISAVKRKERASLRQARPE
>CP032698|5286774:5353693|5292096_5292723_+|AYG82555.1|DBSCAN-SWA
MPASKAAPERAAAPASKAAPARAAAPAPERTPAPARTAAPEPVLWSATQEIPVFNPLPAIPTQQGHDKPVFVDVSGRRGKKLRRLGWLCGLAATGFAVALVGSLLGGNSRAPGLTLPDATKDDAVTAPPRATASQVPQPKQSPKKLVVPSHGVSKAPASKTVKPSKASHGATPVTGHSPVNTKVSPRPSASKKPVTRAVTPTAAKTGA
>CP032698|5286774:5353693|5324658_5326098_+|AYG82580.1|DBSCAN-SWA
MSALEPSDVRVAGHPCAEGDEGGGILGREHRALSMGIVTVVLLIAFEATAVATAMPVAARDLDGVSLYAFAFSAYFTTSLFGMVVAGQWADRRGPLGPLGVGISGFAAGLLWSGTALNMWTFIAGRAVQGLGGGLVIVALYVVMGRAYPARLQPTMMAAFAAGWVVPSVVGPLVAGAVTEQLGWRWVFLGIPALVVFPLALALPATRRMASGPADPSAPVEPFDRRRIGLALAISVGAGLLQYAGQDLGWLSVLPFAAGVAFLGPAVAGRRALLPHGTWRAARGLPSVVLLRGITAGSFVVAESFVPLMLVTQRGLTPTMAGLSLAVGGVTWAVGSSVQARPRMEAYRERMMVVGMVLVALAIVFAPSVLVAAVPVWVVAVAWGVGCFGMGMVITSTSVLLLKLSAPHEAGANSAALQISDGLSNALLLAAGGAAFAALGGGSVSGPTGSHPGAFLAVFLPMAGVALCGTWVAGRVRVG
>CP032698|5286774:5353693|5321498_5323814_+|AYG82578.1|DBSCAN-SWA
MLTYADVLNAPVGKLGAAVDAWSEMTAKLRELSEEAHDGLRVHAETARWAGVNAGVTRAFIVKTVKEFADAEKEAEGAHRLLLDAYTEFKKAKDGLQAIVDGARGNGIVVDARGRVAAREPLVDDAAARHDPDVDFPKALKTQEANVAAWQHKVDALVAACDAADQALRGALAANAPDAHDFTAPRYASLDDEEAGRAVDLARQVTGEGGTARNVEELKQLQTLLDANAHDPEFSTAFYGRLGPQGTLDFYARLSLDATGLGAAGLDRATMVRHVQADLGPMLGLATNPHTTGHLPPAWTTDLMRAGRRPIDVGGFAGPGARVYGYQALGALLRHGTYDKEFLLPIARDMVGFEHQNPKLFQQSVPYDNAMSLNLDKTGGRGFDPLTGLMTSMSNNPRVSAEFFNEAVREDSDGNGIITADDKPVLTKAAGDASSAPLGMVDYLLDKGPGDDLYDARPDARTPYQSALGNAIEAATTGRTPGDTAAKPVEHTAAMASVMEKVVAKIGSDPALVTGEDGAPGKLEGLSGNLGNMAAEYMPDLQATAENGAGQAKPFGVLADFVNSGRVAHFLGAVAQDPDAYGAITNAQQAYTTLLVRDVFAYPENHGDVGEAVRNAVHPGGEIAGMMAEARVQAIYEKHAETDKTFNDAVQNKADWTNRILNSVGAKYIELLPVGGDAVEWLQEDITESLVENRQKDSSGEASQEAADAYAAAEGKAKKSAAGAVRAAGNSVGLAERENREYQGVASSSISVAYSAGRSAVASATPPGGAK
>CP032698|5286774:5353693|5340498_5341866_+|AYG82594.1|DBSCAN-SWA
MDDLLVRLREHLPADAVITDPDITGGYAHDMASFCAAGTPAVVVLPRTVEQVQHVMRTATALRVPVVPQGARTGLSGAANASDGCIVLSLVKMDRILEVNPVDRVAVVEPGVINAVLSREVQKLGLYYPPDPSSWEMCTIGGNIGTASGGLCCVKYGVTAEYVLGLEVVLADGRLMSTGRRTAKGVAGYDLTRLFVGSEGSLGIVVKAVLALRPSPPPQLVLAAEFATAAAACDAVVRIMERGHTPSLLELMDRTTIQAVNRMAHMGLPDSTEALLLAAFDTPDPAADLAAVAELCTAAGATQVVPAEDAAESELLLQARRLSLTALETIKSATMIDDVCVPRSKLAAMIERTSAIAAKYDLTIGVCAHAGDGNTHPVVCFDAADEDESRRARESFDEIMALGLELGGTITGEHGVGVLKKEWLARELGPVGIEMQRAVKHAFDPLGLLNPGKLF
>CP032698|5286774:5353693|5295003_5296161_+|AYG82557.1|DBSCAN-SWA
MTSYVNVPEAAATPAAPPPRPPARDRYFDFLRGLALFRVVLYHLMGWAWLPLAFPSMGVMFALAGNLMARSLKRPAVQVVRGRLRRLLPPMWLLGAVGITGMLAQGWGPDSDGHPAWWWGHLLFWVVPLSDPPYAADLPGIHHVLGDNWGANLAEPLWYLRAYLWFVLLSPLFRALLRKLPWPTIIAPVALCALLEFADLGLPERIDSALTDFATFGACWILGMAHQAGVLRKLPGYLVPSLAPLVMALGYWWAVHGGYSLTGDTELDAIPLAQALWSLGAVLLLLHISPSWETWPDPLRRWDRLITLLNSRAVTIYLWHNLCILVAATVWDDLWSVDALAGAAPFLNSSWPVLVVTWLLIGVCVGCFGWVEDVAAKRRPRLWPV
>CP032698|5286774:5353693|5334909_5336220_-|AYG82589.1|holin|DBSCAN-SWA
MSERSESERSESERSESERSESAGASTAKASTSGASIQLEELTKRYPGSAEPAVDSVTMEIKAGETVVFVGPSGCGKSTTLKMINRLIEPTSGRIRIDDEDVTDIDPVKLRRKVGYAIQSSGLFPHMTVAENIALVPKMVGWSKARVKDRVEEMLDLVGLDPREFHGRYPRQLSGGQQQRVGVARALAADPPVLLMDEPFGAVDPITRDHLQDELIRLQHELHKTIVFVTHDFDEAIKLGDRIAVLRERSHIAQFDTPEAILTNPADDFVSGFVGAGAALKRLNLTRVRDVEMAEFPTVTVDDPPQSIFNKLRSGPHNELLMLDRRNRPYKWLRRGDLMRAKGSLARAGQMVHDTVTRGATLHDALEAVLIDSGGRVAVTGRRGEYIGVVDMETLMNSVHELLEADRLAAIEHQHDLEELRHHQTEQELEGGATQP
>CP032698|5286774:5353693|5344857_5346483_+|AYG82597.1|DBSCAN-SWA
MATVPSDSDGSGAREGYYPDPSIPGYVRYWNGVSWVPGTSRPAPAAGEAPPTPPLGATPAPAPSLAAAPPVTAALAEETGPVFLDEPEASPASAQGSAAPQPAWHADAAHQSGFGGDQDRRVSWGQSVDGRALPESADPRQLPDPRRLPDPRRAEPARPTPTGPSTGPSTGPSTGPSTGPSTGPSTGPSTGPSTGSSTGPFGDPARPAGTVPHQSPQQSAQFAQSANAAQSANAAHPAPSAHSANSARAARPAQPIQSAPPIQPAAPFAGTVPPTAVEPAPVRPQLPTPADPVVAAPTSPAYSAPATPQPQPAQPAQPGPVEPHPGLPGSPMTDGPGGGAASWAQQVHRLAQPDAQAQEPVVPWKPPVDDPFLRAAREQASARPAGLVRRLIARLVDTALLGALVAGLAVPLLARVADHVQQKIDAAKLSGQTVTVYLLDGTTAGLLGIVLGAFLLLGLLYEALPTAKWGRTLGKRLCGVQVRGIESYEPPTFGQAVRRWLVHGVLGLLVIGVVNVAWCLFDRPWRQCWHDKAAHTFVAQG
>CP032698|5286774:5353693|5286774_5287974_+|AYG82551.1|protease|DBSCAN-SWA
MSGPDLCPRPRGLRRGAALTLVFASVLVTAAATNCLPRAEPHPATPAAGPAAAAALDPREGHTTRGGDRTADEVRRAAAEAQADGESATRAAEEVVGRSGDRWGAVYDKAEYEQYADALEGRYTGVGLWVARAAGGHIQVTRVQPGGPAARAGVRAGDVLRTIDGWSADGKPVTDVVARLRGDAAGSKVAIGLGRGPLTWTRTLDRAVLGTEDVAVENLSDTVVMIRVTAFTKGSGERVRAAVRRAPAGAGILLDLRGNSGGLVAEAVTAASAFLPGGLVATYDVHGKQRALYASGGGDAARPLVVVIDGGTMSAAELLTGALQDRGRAVTVGSRTFGKGSVQMPTGLVGGSVAELTVGHYRTPSGHGLDGKGITPDLPVTEHPLEHARTVLSGLGGTS
>CP032698|5286774:5353693|5318545_5320864_+|AYG82576.1|DBSCAN-SWA
MSNDAATATVEGATSVAGPEQQPPAHGIGASLAPVDARAKTEGTFPYAADLWAEGLLWAAVLRAPHAYARIVSIDTAAAAAMPGVRAVVTHADVPGDPAFGRRIADRPVFAAEYVRHHGEPIAAVAADHPDTARLAAAAIAVEYEVLEPVTDPEKAFTAEPLHPDGNLIRHIPLQYGDPEVTGDVVVEGLYRIGRQDPAPIGAEAGLAVPRPDGGVELYTASTDPHGDRDAAAVCFGLEPDRVKVVVTGVPGATGDREDLGFQLPLGLLALKTGCPVKLTATREESFLGHAHRHPTLLRYRHHADAEGRLVKVEAQILLDAGAYAEASAESLAAAVAFACGPYVVPHAFVEGWAVRTNNPPSGHVRGEGAMQVCAAYEGQMDKLAAKLGIDPAELRMRNVLATGDLLPTGQTVTCPAPVAELLGAVRDFPLPTLPKDAPEDDWLLPGGPEGAGEPDAVRRGVGYALGMVHMLGAEGTDEVSTATVKVHDGVATVICAAVETGQGFTTLARQIVQETLGIEEVHVAPVDTDQPPAGPATHGRHTWVSGGAVERAAKMVRTQLLQPLAHKFGMSTELLQIADGKITSYDGVLSTTVTEAMDGKELWATAQCRPHPTEPLDETGQGDAFVGLAFCAIRAVVDVDIELGSVRVVELAVAQDVGRILNPRQLTARIEAGVTQGVGAALTENLRTVRGRIRHPDLTGYALPTALDAPDIRIVKLVEERDVVAPFGAKAASAVPVVTCPAAIASAVRAATGRPVNRLPIRPQAAVVQQG
>CP032698|5286774:5353693|5346628_5347468_+|AYG82598.1|DBSCAN-SWA
MSTDQPPPGQPPEDDPFLKKPSEPPRSGSPYGGTQPPPGRPPGDSPYGAGPPSGGDGPYGAPPPPSGAGGPYGAPPPRSGAGGPYGGPPPPGGGSPYGSAPPPPSDPYGGQYGGVDPLAGMPPLADFGKRFLARFIDFLIIAIPLGLIEWATSNRVVISTSDNGDSGTEVISKAYSGSGLLWLLITLVVYIGYDTLMVSKSGQTLGKKLLGLRVAMLNDGSVPTTNAALARAAVLWAPFVLCCYCLWDIILGITIVTDKPYRQGWHDKAGKTVVVSTPQ
>CP032698|5286774:5353693|5330722_5332060_-|AYG82584.1|DBSCAN-SWA
MSGPGGHRDRSGPGGHHDRGPLTAVLTANAISASGSSLTLIGVPWFVLETTGSPGRAGVVAFCATLPIVVSALVGGPVIDRAGRRRVSVGSDVVCGLAVAAIPLLHQAGLLAFWLLCALMALGGLAHTPGVTARYVLLPDLARRSGTTLSRAASGYDAVARGARMTGAALAGVLIALTGAGNVLLVDGATFAVSAALVAAGLRHVPEARPRRDAPPVSVRTYKAELREGYAYLARTRLLIAVVAMVMLMNGTDQGWNAVLLPVHAERHLGGAPQLGLLAALFGAGGLSGALLYGLVGHRFRRRTVFSVCVLLCGAPRYAVAALTGTTLPLAATMVVAGLASGSLNPILTTVIYEKVPDALRSRVAGVLTAGCELAMPLGGLAAGFLVESAGLRGALLVVGGVYLLATLSPLVFPAWKDMDAGAVSRTGPGRPSATPEARTPHPSA
>CP032698|5286774:5353693|5348244_5350635_+|AYG82600.1|DBSCAN-SWA
MTSSRRAARAAAVLVALATAGATGSAYATAQADSKAPAPVQRQDPSRANGQEHNLKGPFSDQQAQQRQAALEQVISGKKKVEKRGASDVVKLSDKKYVELGREKTDKIFTILVEFGDQVDNTTMYDPDGPDGPKPPQPKYGGTPGPAHNQIAKPDRSKDNSTAWQADYNQKHFQDLYFGTGKNVNSLKTYYEKTSSGRYSVDGQVTDWVKIPYNEARYGSNYCGQTNCANVWDTVRDGVNAWVADQKAKGQTDAQIKATLGQYDQWDRNDYNNNGNFNEPDGYIDHFQIVHAGEDESAGGGAQATNALWAHRWYAYGTDAGKTGPANNKAGGTQIGDTGMWVGDYTMQPENGGLGVFAHEYGHDLGLPDLYDTTNTAENSVGFWSLMSAGSWLGTGKDSIGDLPGDMTAWDKLQLGWLDYASVKAGSKITAKLGVSEYNTKNNQALVVELPKKEVTTTVVKPVEGSKQWWSGMGDNLNNTLTRSVDLTGKSKASLDLSGWWDIEKDYDFLYTEVSTDDGASWNAIDGTADGKAITRDSSDKPALTDASGAYKKLSYPLDQYAGHKIQLRFRYQTDGGAGGKGFTADAISVTADGTAVVTDGAEAGDNGWAAKNFTRIGESFTNDYPQYYLAENRQYVSYDTTLKVGPYNFGFSTTRPSWVEHYPYQRGLLIWLWDTSQKDNNVSAHPGQGLILPVDAHAKPLKWADGTLLRNKIQPFDAPFSQYRTDAFTLHKADVATKIKSQAGVPVFDDHQGTYWYAENPTGSVKVPDTKTRISIVDQPWNGQTITVKVGTSTK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYG82551.1|5286774_5287974_+|protease	putative CtpA-like serine protease	NA	NA	NA	NA
AYG82552.1|5288008_5288536_+	SsrA-binding protein	W5RAM5	Staphylococcus_phage	3.4e-34	50.3
AYG82553.1|5289241_5290480_-	hypothetical protein	NA	NA	NA	NA
AYG82554.1|5290582_5291593_+	HTH-type transcriptional regulator BenM	NA	NA	NA	NA
AYG82555.1|5292096_5292723_+	hypothetical protein	NA	NA	NA	NA
AYG82556.1|5292853_5295007_+	Poly-beta-1,6-N-acetyl-D-glucosamine synthase	NA	NA	NA	NA
AYG82557.1|5295003_5296161_+	hypothetical protein	NA	NA	NA	NA
AYG82558.1|5296304_5297642_+	Nitrate/nitrite transporter NarK	NA	NA	NA	NA
AYG82559.1|5297745_5298924_+	hypothetical protein	NA	NA	NA	NA
AYG82560.1|5298856_5299405_-	hypothetical protein	NA	NA	NA	NA
AYG82561.1|5299623_5300184_+	hypothetical protein	NA	NA	NA	NA
AYG82562.1|5300311_5300875_+	ECF RNA polymerase sigma factor SigL	NA	NA	NA	NA
AYG82563.1|5300871_5301633_+	hypothetical protein	NA	NA	NA	NA
AYG82564.1|5301750_5304162_+	DNA helicase IV	NA	NA	NA	NA
AYG82565.1|5304580_5306014_+	NAD-dependent malic enzyme	NA	NA	NA	NA
AYG82566.1|5306413_5306695_+	DNA-binding protein HU	Q6QIE5	Burkholderia_phage	5.9e-09	42.9
AYG82567.1|5307175_5308516_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1	NA	NA	NA	NA
AYG82568.1|5308770_5309331_+	hypothetical protein	NA	NA	NA	NA
AYG82569.1|5309387_5309681_+	hypothetical protein	NA	NA	NA	NA
AYG82570.1|5309925_5311224_+	Cyclodextrin-binding protein	NA	NA	NA	NA
AYG82571.1|5311220_5312180_+	Inner membrane ABC transporter permease protein YcjO	NA	NA	NA	NA
AYG82572.1|5312176_5313031_+	Inner membrane ABC transporter permease protein YcjP	NA	NA	NA	NA
AYG82573.1|5313599_5315264_+	Beta-hexosaminidase	A0A076G5S5	Staphylococcus_phage	5.4e-09	26.3
AYG82574.1|5315631_5316498_+	Carbon monoxide dehydrogenase medium chain	NA	NA	NA	NA
AYG82575.1|5316494_5318549_+	Nicotinate dehydrogenase small FeS subunit	A0A0P0IVM8	Acinetobacter_phage	5.9e-13	36.2
AYG82576.1|5318545_5320864_+	putative xanthine dehydrogenase subunit D	NA	NA	NA	NA
AYG82577.1|5321088_5321481_+	hypothetical protein	NA	NA	NA	NA
AYG82578.1|5321498_5323814_+	hypothetical protein	NA	NA	NA	NA
AYG82579.1|5323837_5324368_+	hypothetical protein	NA	NA	NA	NA
AYG82580.1|5324658_5326098_+	Multidrug efflux pump SdrM	NA	NA	NA	NA
AYG82581.1|5326812_5328639_+	Reverse gyrase	I4AZM6	Saccharomonospora_phage	1.1e-92	37.9
AYG82582.1|5329128_5329773_+	HTH-type transcriptional regulator KipR	NA	NA	NA	NA
AYG82583.1|5330001_5330790_+|protease	Lon protease	NA	NA	NA	NA
AYG82584.1|5330722_5332060_-	putative multidrug-efflux transporter	NA	NA	NA	NA
AYG82585.1|5332056_5332233_-	hypothetical protein	NA	NA	NA	NA
AYG82586.1|5332286_5332913_-	hypothetical protein	NA	NA	NA	NA
AYG82587.1|5333051_5334035_-	Osmoprotectant-binding protein OsmX	NA	NA	NA	NA
AYG82588.1|5334034_5334913_-|holin	Choline transport system permease protein OpuBB	NA	NA	NA	NA
AYG82589.1|5334909_5336220_-|holin	Glycine betaine/carnitine/choline transport ATP-binding protein OpuCA	A0A285PWH2	Cedratvirus	3.7e-21	28.1
AYG82590.1|5336212_5336860_-|holin	Choline transport system permease protein OpuBB	NA	NA	NA	NA
AYG82591.1|5336885_5337371_-	Regulatory protein AsnC	NA	NA	NA	NA
AYG82592.1|5337492_5338638_+	4-hydroxyphenylpyruvate dioxygenase	NA	NA	NA	NA
AYG82593.1|5338756_5340400_-	Lipopolysaccharide assembly protein B	NA	NA	NA	NA
AYG82594.1|5340498_5341866_+	putative FAD-linked oxidoreductase	NA	NA	NA	NA
AYG82595.1|5342053_5342542_-	Sporulation-specific cell division protein SsgB	NA	NA	NA	NA
AYG82596.1|5343294_5344473_-	hypothetical protein	NA	NA	NA	NA
AYG82597.1|5344857_5346483_+	hypothetical protein	NA	NA	NA	NA
AYG82598.1|5346628_5347468_+	hypothetical protein	NA	NA	NA	NA
AYG82599.1|5347453_5347825_-	hypothetical protein	NA	NA	NA	NA
AYG82600.1|5348244_5350635_+	Immune inhibitor A	NA	NA	NA	NA
AYG82601.1|5350794_5351094_+	hypothetical protein	NA	NA	NA	NA
AYG82602.1|5351124_5351712_-	Nicotinamidase/pyrazinamidase	NA	NA	NA	NA
AYG82603.1|5351822_5353151_-	Nicotinate phosphoribosyltransferase pncB1	NA	NA	NA	NA
AYG82604.1|5353387_5353693_+|protease	ATP-dependent Clp protease adapter protein ClpS	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>CP032698|6662201:6668338|DBSCAN-SWA
CGTGAGCGAGGAGCTGGAGCTGAAGCCGGCCTTGGAAGCCGTCCTGATGGTCGTCGACGAGCCCGCGAGCGAGGAGCACCTCGCCAAGGTCCTGGAACGCCCCAGAAGGGCCGTGGCGGACGCCCTGCGGGAGCTGGCCGACGAGTACACGGCGCAGGGCCGCGGCTTCGAGCTGCGGCTGGTCGCGGGCGGCTGGCGGTTCTACAGCCGGGCCGCGTACGCCGACGCCGTCGAGGGCTTCGTCCTGGACGGCCAGCACGCCCGTCTCACCCAGGCCGCCCTGGAGACCCTCGCGGTCGTCGCCTACCGCCAGCCGGTGAGCCGCTCGCGGGTCTCCGCGGTGCGCGGAGTCAACTGTGACGGGGTCATGCGGACCCTGCTCCAGCGCGGTCTGGTCGACGAGGCGGGCACGGAACCCGAAACAGGTGCGATCCTGTACAGGACGACGAACCACTTTCTGGAGCGGATGGGCCTGCGCGGCCTGGACGAGCTCCCGGAGCTGGCGCCCTTCCTCCCCGAGGCGGACGCGATCGAGGCCGAGACCCTGGAGGGTGTGCCGTCGTTCGACCCGGACGCGCCCGACGCGCCGGAAACCCCCGCAGACGACAAGACGGAAATGTGATGCGAAGCAGCAGCGGCAGGAACAGCAGCGGAAACAACGGCGGGAGCCGTGGTGGCAACAGCGGCGGCCGCGGCAGCAGTGGCGGTGGCGGCGGCCGGGGCGGATCCGGCGGTGGCCGGGACGGCCAGCGCCAGGGCGGCGGCCCGCGCCAGAGCGGCAGCGGCAAGCCGCGTCCGCTGCGCCCCGAGGAGCGCACCTACGACGTGGGCGGCGACGCCCCCCGCGGTGGACGCGGCGCTTCCGCGCGCGGCGGCGCCAAGGGCGGCCCCAAGGCGCCCCAGGGCGGCACCCCGGTCCGCCGCGGCCCGCACGGCCAGCGCCTGGGCCAGGCCCGCCCGCGCGAGCTCGACGCCAAGATCGAGCAGCGCAACCGGGACCGGTACGCGGACAAGCCGGACGTGAAGACCCCCAAGACCTTCCCCGGCGCCGAGCAGGAGGGCGAGCGCTTGCAGAAGGTGCTGGCCAGGGCCGGCATGGGCTCGCGCCGCGCCTGCGAGGAGCTGATCGAGCAGGCCCGTGTCGAGGTCAACGGCGAGATCGTGCTCGAACAGGGCAAGCGCGTCGACCCCGAGCGGGACGAGATCAAGGTGGACGGCCTCACCGTCGCCACCCAGTCGTACCTCTTCTTCGCGCTGAACAAGCCGGCCGGCGTCGTCTCCACCATGGAGGACCCGGACGGCCGCCAGTGCCTCGGTGACTACGTCACCAACCGCGAGACCCGCCTCTTCCACGTGGGCCGTCTCGACACCGAGACCGAGGGCATCATCCTGCTCACCAACCACGGCGAGCTGGCCCACCGTCTGACCCACCCCAAGTACGGCGTGAAGAAGACCTACTTGGCGGCCATCACGGGCCCGCTGCCGCGCGAGATCGGCAAGCGGCTCAAGGAGGGCATCCAGCTGGAGGACGGTTACGCGCGGGCCGACGCCTTCCGCGTCATCCAGCAGACCGGCAAGAACTACCTCGTCGAGATCGAGCTCCACGAGGGCCGCAAGCACATCGTGCGCCGCATGATGGCCGAGGCCGGCTTCCCGGTCGAGAAGCTGGTGCGCGTCGGGTTCGGCCCGATCGGGCTCGGCGACCAGAAGTCCGGCTGGCTGCGCCGCCTCACCAACACCGAGGTCGGCATGCTGATGCGCGAGGTCGAGCTTTAAGGACCCCCAACACCCGCCGCCGGAGCCCGGCTTCCCCGTCCTGGGGGAGCCGGGCTTTCGCGTCGTGTGCGCCCCCGCAACTTTGTGCGCCCTTCTGAACAACCTTGTGCGCCCACCCCTGACCTCTTTATAGTCACAGCGACCATTAAGGAGGTCGGTGTGTCCCTCACCTGGACCGAGACACTCGGGTTCGTCACCGGCGCGCTCTGCGTCTGGCTGGTGGCCCGCCGGCACGTCGCCAACTGGCCGGTGGGCATCGCCAACAACCTGTTCTTCATCGTGCTCTTCCTCCAGGCGGGCCTGTACGCGGACGCCGGACTCCAGGTCGTCTTCATCGCCCTCGCCGGGTACGGCTGGTGGACCTGGACCCACGGGGGTGGACCAGGTTCCGGCACGCTTCCGGTCCGGCGCACGACCCGCACCGAGTGGCTGGGGCTGCTCACGGCGGGGGCGGTGGGGACCGTGGCGCTGACGTTCCTGCTCGCCGCGGCCACCGACTCGACCGTCCCGTTCTGGGACGCGCTCACCACCGCCCTGTCCCTGACGGCGACGTACGGCCAGTGCGAGAAGCTCCTCGAATCCTGGTGGCTGTGGATCGCGGCGGACGTGATCTACATCCCGCTCTACGCCTACAAGGAGCTCTACGCGACCTCGCTCCTGTACGTCGGCTTCCTGGCCCTGTGCCTGATCGGGCTGCGGGGCTGGCGGCGCGAACTGGGCTTCAGGCCCCGGCGACTTGACGAGGTGACGGTGTGAAGCGGCATCAACACGGCCTGGTCCTGGGCAAGTTCTATCCGCCGCACGCCGGCCACCACCACCTGGTGCGCACCGCGGCCGCCCACTGCGAACGGCTCACCGTGCTGGTGTGCGCCGCCTCCGTCGAGACGATCCCGCTGGCCGAGCGAGTGCGGTGGATGCGGGCGGCACATCCGGACGCCCGCGTCCTGGGCGCCGTCGACGACATCGGGGTGGACCTGCACGACCCGGTGATATGGGACGCCCACATGGCCGTCTTCCGCGGCGCCGTCCCCGAGCGCGTCGACGCGGTGTTCACCTCCGAGTCCTACGGCGACGAACTCGCCCGCCGCTTCGGCGCCGAGCACGTCCTGGTCGACCTCGACCGCACCCTGTTCCCCGTCTCCGGCACCGCCGTGCGCAAGGACCCGGTGGGCAGTTGGGACTTCCTCGACGCGCCGGTGAGGGCCTGGCTCACCCGGCGCGTGGTCGTGCTCGGCGCCGAGTCCACCGGCACCACCACCCTGGCCCGCGCCCTCGCCGCGCACTACCGCGCGCGCGGCGGGGTCTGGGCGCGCACCCGCTGGGTCGAGGAGTACGGACGCGAGTACAGCGAGGGCAAGCTGGCCGCGCTGCGCGCCCGCTACCCGCAGGCGTGCTGGGAGGACGTCGAGTTCGGCTCGGACGAGTTCCCGGTGATCGCCGAGCGGCAGAACGAGCGCGAGAACGCCGCGGCCGGACTCGGCTCGCCCGTGCTGTTCTGCGACACCGACTCCTTCGCCACCACCGTGTGGCACGAGCGCTACGTGGGCCGGCGCGACCCGCGCGTCGACGCGGTCGCCGAACGGGCCGCGGCCCACCACCTGTGGCTGCTCACCGACCACGAAGGGGTGCCCTTCGAGGACGACGGGCTGCGCGACGAGGAGGAGCTGCGGCCCTGGATGACCGACCGGTTCCGGGCCGAACTCACCCGTACCGGACGGGAGTTCATCGAAGTGCGCGGCCCGCACGAGGAACGCCTGGCGACCGCCGTGGCCGCCGTGGACGCGCTGCTCGACCGGGGCTGGGAGCTCGCCGACCCGCTGCCGGAGCGGCGATGACCGCCGTCGGCCCCCGGGCCCGGGAGGGGGGCGCCCGGGAGCCGGCGGCCAAGGTGCCCGAGGGATACGACCCGCACGCCTTCGCGCCGTTCGCCGTCACCGTGGACCTCGCCGTCTTCACGGTCCGCGAGGGCGCCCTGCACGCACTGCTCATCCGGCGCGGCCAGGACCCGTACGCGGGCGCCTGGGCGCTGCCCGGCGGTTTCGTGCTGCCGCGCGAGTCCGCCGAACTCGCGGCCCGGCGCGAACTGGCCGAGGAGACGGGCCTCGCGGACGACGTGGTGGCCACCCTCCACCTGGAACAACTGCGCACCTACAGCGAGCCGGACCGCGACCCCAGGATGCGGGTCGTCTCGGTCGCGTACACCGCGCTCGTGCCCGACCTGCCCGAACCGCGCGGCGGCGGCGACGCGGCGCACGCCGAGTGGGTCGCCTTCGGCACCCGCGGGCGCCTCGCCTTCGACCACGCCGACATCCTCGCCGACGCCCACGAACGCGTCGGCGCCAAGCTCGAATACACCTGCCTCGCCACCTCGTTCTGCCCGCCGCAGTTCACCCTCGGCGAGCTCCAGCAGGTGTACGAGACGGTCTGGGGCACCGCGCTCGACCGCCCCAACTTCCGCCGCAAGGTGCTGGCCACGCCCGGCTTCGTCGAGCAGGTGGCAGGTGCTTCGCGGCTGACCGGCGGCCGGGGCAAACCGGCCGCGCTCTACCGGGCGGGCCCCGCGACCGCGCTGCACCCGCCCCTGATGCGCCCGGAGGGACGACCAACATGAACCGTTCCGCTCGACAGACGGCCACCGGTGCCTTGATCGGCCTCGCACTGGGGGACGCCCTCGGCTTCCCCACCGAGTTCGACGACGTGCCGGCGATCCTCGCCAAGTGCGGGCCCTGGCGCGAGATGGCGCTGCCCACACCCGCGATCGTCACCGACGACACCCAGATGACCCTCGCCCTCGGCCGCGGCATCCGTACCGCCATGGACCGCGGGCTGCTCGGCCCGCTGCGCCTGGAGCGGCCGGTCCGCGAGGAGTTCGTCGACTGGTACCACTCGCCCGAGAACAACCGCGCCCCCGGCCGCACCTGCCTGGTGGCCTGCGCCCAACTGGACCGGGGGCTGCCCTGGCAGCAGGCCACCCAGCTCGGCTCCAAGGGCTGCGGCGCCAACATGCGGGTCACGCCCATCGGTCTCGTGCCGGGTTTGAGCGAGGAACAGCGGGCGGGCGCCGCCCAGTTGCAGGCCGCCCTCACCCACGGCCACCCCACCGCCCTCGCCGCCTCCGACCTCACCGCCCGCGCGGTGTTCCTGCTCGCCCAGGGCGCCGACCCGATGGGCCTGGTCGGCCAGTTGCGCTCGTACGCCTACGAGAACCGCAGCCGCTATCACGACCGCTGGCTCGGCGACCTGTGGACGCGGGCGCAGGACCCGACCCCGGGCCACTTCATCGCGCGCGGCTGGGACGAGTGCCTCGACGCCCTCGACCGGGTACTGAAGGCGCTCCGCGCGCCCTCGCCCGAGACCGACCCCTGCCTGGACACCGGCGACGGCTGGGTGGCCGAGGAGGCCTTCGCCACGGCTCTGCTCTGCTTCCTGCTCTTCCCCGACGAACCCCTCACCGCGCTGCGCCGGGCGGCCTGCACCCAAGGCGATTCGGACTCCATCGCCTGCTTGACCGGCGCGTTCGTCGGCGCCCACCTCGGGGTGGCGGCCTGGCCCAAGGAGTGGGCGGAGCGCATCGAGTACCGCAGCGAACTGCTGACCCTAGGGGCGCTCTGGGACGCGTGAGCCCAAACGGCGTCACCCACGACGCACGCCGTGCCGCACGACGTCGTCGTACGCCCCCGCCTTCAGGGCCGACTCGCGGCGCACGCGGAACAGGAACTCCGCCACCCGGGCCCGGTCGGGCTCGGGCGGCAGGGGAGAGGTGGTGGCCGCCTCGTCGGCCTCGGTCGCCCGGCGGGCCATCCAGGACTCCACCTCGGGCCAGGACACCTCGCCGCGCCTGACCGCCAGGAGGCGCTCCCGTTCGGCGCCCACGTCGATGGCGAGCGCGCCGGTGCGCAGCAGATCGCGGCAGCTCGTCAGGAGCCGCAGCAGATGCATGGCGTGCTTCCACCGGGGCGCGCCGAACCGGCGGACGTCGGCGTCGAGCTTCTTGCGCTGGCCGAGCGCGTAGCGCACGAACGTCTGGTGGGCCCGCCGGGACAGGAACGCCTCGCGCAGGGCGAGCAGTTCGCGTCCCGTGGCGTCGATGTGCTCGACCAGCGGGGAGTGCAGGCACTCCAGGATGTTCGGGTTGGCGCGCAGGGCCAGCTCGCAGAACCGCTCCAGCTCCCAGCCGAACTGCTCGGGGGCCGGGCCCTCGACATGGGACGGCGGCTTCTCGAAGCCCCAGAACAGCGCGGTGGGCGCTAGATAGATCCCGCGGACGTCGGTGTCGCTGTCCTCGGTCGCGAGGCCGAAGGCGCGCGAGCCCATGACGCAGGAGTAGACGGTGTGGTCGGCGACGAGCTCTTCGGGCGTCAT

Protein sequences of DBSCAN-SWA_3

>CP032698|6662201:6668338|6662201_6662822_+|AYG83759.1|DBSCAN-SWA
MSEELELKPALEAVLMVVDEPASEEHLAKVLERPRRAVADALRELADEYTAQGRGFELRLVAGGWRFYSRAAYADAVEGFVLDGQHARLTQAALETLAVVAYRQPVSRSRVSAVRGVNCDGVMRTLLQRGLVDEAGTEPETGAILYRTTNHFLERMGLRGLDELPELAPFLPEADAIEAETLEGVPSFDPDAPDAPETPADDKTEM
>CP032698|6662201:6668338|6662821_6663976_+|AYG83760.1|DBSCAN-SWA
MRSSSGRNSSGNNGGSRGGNSGGRGSSGGGGGRGGSGGGRDGQRQGGGPRQSGSGKPRPLRPEERTYDVGGDAPRGGRGASARGGAKGGPKAPQGGTPVRRGPHGQRLGQARPRELDAKIEQRNRDRYADKPDVKTPKTFPGAEQEGERLQKVLARAGMGSRRACEELIEQARVEVNGEIVLEQGKRVDPERDEIKVDGLTVATQSYLFFALNKPAGVVSTMEDPDGRQCLGDYVTNRETRLFHVGRLDTETEGIILLTNHGELAHRLTHPKYGVKKTYLAAITGPLPREIGKRLKEGIQLEDGYARADAFRVIQQTGKNYLVEIELHEGRKHIVRRMMAEAGFPVEKLVRVGFGPIGLGDQKSGWLRRLTNTEVGMLMREVEL
>CP032698|6662201:6668338|6664728_6665811_+|AYG83762.1|DBSCAN-SWA
MKRHQHGLVLGKFYPPHAGHHHLVRTAAAHCERLTVLVCAASVETIPLAERVRWMRAAHPDARVLGAVDDIGVDLHDPVIWDAHMAVFRGAVPERVDAVFTSESYGDELARRFGAEHVLVDLDRTLFPVSGTAVRKDPVGSWDFLDAPVRAWLTRRVVVLGAESTGTTTLARALAAHYRARGGVWARTRWVEEYGREYSEGKLAALRARYPQACWEDVEFGSDEFPVIAERQNERENAAAGLGSPVLFCDTDSFATTVWHERYVGRRDPRVDAVAERAAAHHLWLLTDHEGVPFEDDGLRDEEELRPWMTDRFRAELTRTGREFIEVRGPHEERLATAVAAVDALLDRGWELADPLPERR
>CP032698|6662201:6668338|6664135_6664732_+|AYG83761.1|DBSCAN-SWA
MSLTWTETLGFVTGALCVWLVARRHVANWPVGIANNLFFIVLFLQAGLYADAGLQVVFIALAGYGWWTWTHGGGPGSGTLPVRRTTRTEWLGLLTAGAVGTVALTFLLAAATDSTVPFWDALTTALSLTATYGQCEKLLESWWLWIAADVIYIPLYAYKELYATSLLYVGFLALCLIGLRGWRRELGFRPRRLDEVTV
>CP032698|6662201:6668338|6666583_6667597_+|AYG83764.1|DBSCAN-SWA
MNRSARQTATGALIGLALGDALGFPTEFDDVPAILAKCGPWREMALPTPAIVTDDTQMTLALGRGIRTAMDRGLLGPLRLERPVREEFVDWYHSPENNRAPGRTCLVACAQLDRGLPWQQATQLGSKGCGANMRVTPIGLVPGLSEEQRAGAAQLQAALTHGHPTALAASDLTARAVFLLAQGADPMGLVGQLRSYAYENRSRYHDRWLGDLWTRAQDPTPGHFIARGWDECLDALDRVLKALRAPSPETDPCLDTGDGWVAEEAFATALLCFLLFPDEPLTALRRAACTQGDSDSIACLTGAFVGAHLGVAAWPKEWAERIEYRSELLTLGALWDA
>CP032698|6662201:6668338|6665807_6666587_+|AYG83763.1|DBSCAN-SWA
MTAVGPRAREGGAREPAAKVPEGYDPHAFAPFAVTVDLAVFTVREGALHALLIRRGQDPYAGAWALPGGFVLPRESAELAARRELAEETGLADDVVATLHLEQLRTYSEPDRDPRMRVVSVAYTALVPDLPEPRGGGDAAHAEWVAFGTRGRLAFDHADILADAHERVGAKLEYTCLATSFCPPQFTLGELQQVYETVWGTALDRPNFRRKVLATPGFVEQVAGASRLTGGRGKPAALYRAGPATALHPPLMRPEGRPT
>CP032698|6662201:6668338|6667609_6668338_-|AYG83765.1|DBSCAN-SWA
MTPEELVADHTVYSCVMGSRAFGLATEDSDTDVRGIYLAPTALFWGFEKPPSHVEGPAPEQFGWELERFCELALRANPNILECLHSPLVEHIDATGRELLALREAFLSRRAHQTFVRYALGQRKKLDADVRRFGAPRWKHAMHLLRLLTSCRDLLRTGALAIDVGAERERLLAVRRGEVSWPEVESWMARRATEADEAATTSPLPPEPDRARVAEFLFRVRRESALKAGAYDDVVRHGVRRG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AYG83759.1|6662201_6662822_+	Segregation and condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	1.0e-08	29.5
AYG83760.1|6662821_6663976_+	putative RNA pseudouridine synthase	NA	NA	NA	NA
AYG83761.1|6664135_6664732_+	Nicotinamide riboside transporter PnuC	A0A0F6YPU8	Sinorhizobium_phage	1.9e-09	30.9
AYG83762.1|6664728_6665811_+	Trifunctional NAD biosynthesis/regulator protein NadR	A0A192Y7D8	Salmonella_phage	1.3e-32	31.4
AYG83763.1|6665807_6666587_+	Bifunctional NMN adenylyltransferase/Nudix hydrolase	A0A0E3JJF3	Streptomyces_phage	2.3e-18	46.2
AYG83764.1|6666583_6667597_+	ADP-ribosyl-[dinitrogen reductase] glycohydrolase	A0A1I9SA26	Rhodococcus_phage	1.3e-24	31.5
AYG83765.1|6667609_6668338_-	hypothetical protein	A0A1J0GW18	Streptomyces_phage	1.6e-13	35.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage
CP032698.1|AYG82579.1|5323837_5324368_+|hypothetical-protein	5323837_5324368_+	176 aa aa	NA	NA	NA	5286774-5353693	yes

Protein sequences of CP032698.1|AYG82579.1|5323837_5324368_+|hypothetical-protein

>CP032698.1|AYG82579.1|5323837_5324368_+|hypothetical-protein
MSVLTAVWAMAGCSADSPVPSLPKSLCWGAFAGSAVAPIVPTGDATTVENNRPFDVFAPTDQTTYCTVRVDNDARFIAWAELRRSGKGTDWNHSARHLGTRIEAGDEAFVWGGDAAAVFECGRPDVARGPTLPASAKYIELQLTADRAPETQRTRDVLTTLMRQYVHFAKQRLKCR

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
CP032698_14	Orphan	14.2|2936098|20|CP032698|PILER-CR	2936098-2936117	20	5343067-5343086	2
CP032698_18	Orphan	18.1|3355695|29|CP032698|CRISPRCasFinder	3355695-3355723	29	5313452-5313480	2
CP032698_18	Orphan	18.3|3355706|20|CP032698|PILER-CR	3355706-3355725	20	5313460-5313479	2
CP032698_26	Orphan	26.1|3743825|33|CP032698|CRISPRCasFinder	3743825-3743857	33	5326535-5326503	2
CP032698_47	Orphan	47.2|4480782|32|CP032698|PILER-CR,CRT	4480782-4480813	32	5326249-5326218	2
CP032698_50	Orphan	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	5306846-5306826	2
CP032698_50	Orphan	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	5306990-5306970	2
CP032698_50	Orphan	50.1|4603161|21|CP032698|PILER-CR	4603161-4603181	21	5342971-5342991	2
CP032698_59	Unclear	59.2|5075273|35|CP032698|CRISPRCasFinder	5075273-5075307	35	5326535-5326501	2
CP032698_60	Orphan	60.1|5118893|30|CP032698|CRISPRCasFinder	5118893-5118922	30	5343098-5343069	2
CP032698_95	Orphan	95.1|7390256|34|CP032698|PILER-CR	7390256-7390289	34	5306846-5306813	2
CP032698_96	Orphan	96.2|7574068|32|CP032698|CRISPRCasFinder	7574068-7574099	32	5326305-5326274	2
CP032698_96	Orphan	96.2|7574068|32|CP032698|CRISPRCasFinder	7574068-7574099	32	5326362-5326331	2
CP032698_96	Orphan	96.2|7574068|32|CP032698|CRISPRCasFinder	7574068-7574099	32	5326419-5326388	2
CP032698_96	Orphan	96.2|7574068|32|CP032698|CRISPRCasFinder	7574068-7574099	32	5326476-5326445	2

1. spacer 14.2|2936098|20|CP032698|PILER-CR matches to CP032698 position: 5343067-5343086, mismatch: 2

gaagcgaccccgacccgcac	CRISPR spacer
gaagcgaccacggcccgcac	Protospacer
********* **.*******

2. spacer 18.1|3355695|29|CP032698|CRISPRCasFinder matches to CP032698 position: 5313452-5313480, mismatch: 2

ccagccacgcacggtgtgaggccgaaagg	CRISPR spacer
ccagccacgcacggtgcgaggacgaaagg	Protospacer
****************.**** *******

3. spacer 18.3|3355706|20|CP032698|PILER-CR matches to CP032698 position: 5313460-5313479, mismatch: 2

gcacggtgtgaggccgaaag	CRISPR spacer
gcacggtgcgaggacgaaag	Protospacer
********.**** ******

4. spacer 26.1|3743825|33|CP032698|CRISPRCasFinder matches to CP032698 position: 5326535-5326503, mismatch: 2

ccagccacgcacggcccgcagccgaaagcgggt	CRISPR spacer
ccagccacgcaaggcccgcagccgaaaacgggt	Protospacer
*********** ***************.*****

5. spacer 47.2|4480782|32|CP032698|PILER-CR,CRT matches to CP032698 position: 5326249-5326218, mismatch: 2

agaagcgggcacggtccgcaggttcgagaggg	CRISPR spacer
agaagcgggcacggtccgcagcttcgagcggg	Protospacer
********************* ****** ***

6. spacer 50.1|4603161|21|CP032698|PILER-CR matches to CP032698 position: 5306846-5306826, mismatch: 2

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggtccgcag	Protospacer
******** *****.******

7. spacer 50.1|4603161|21|CP032698|PILER-CR matches to CP032698 position: 5306990-5306970, mismatch: 2

ccagccccccacggcccgcag	CRISPR spacer
ccagccccgcacggtccgcag	Protospacer
******** *****.******

8. spacer 50.1|4603161|21|CP032698|PILER-CR matches to CP032698 position: 5342971-5342991, mismatch: 2

ccagccccccacggcccgcag	CRISPR spacer
ccagccacccccggcccgcag	Protospacer
****** *** **********

9. spacer 59.2|5075273|35|CP032698|CRISPRCasFinder matches to CP032698 position: 5326535-5326501, mismatch: 2

ccagccacgcacggtccgcagccgaaaacgggttt	CRISPR spacer
ccagccacgcaaggcccgcagccgaaaacgggttt	Protospacer
*********** **.********************

10. spacer 60.1|5118893|30|CP032698|CRISPRCasFinder matches to CP032698 position: 5343098-5343069, mismatch: 2

acccgctttcgggtgcgggccgtggtcgct	CRISPR spacer
accccctttcgtgtgcgggccgtggtcgct	Protospacer
**** ****** ******************

11. spacer 95.1|7390256|34|CP032698|PILER-CR matches to CP032698 position: 5306846-5306813, mismatch: 2

ccagccccgcacggtccgcggacgaatgcgggtt	CRISPR spacer
ccagccccgcacggtccgcagacgaaagcgggtt	Protospacer
*******************.****** *******

12. spacer 96.2|7574068|32|CP032698|CRISPRCasFinder matches to CP032698 position: 5326305-5326274, mismatch: 2

gaagcgaccgcggtccgtaggttcgagagggt	CRISPR spacer
gaagcgaccgcggtccgcaggttcgagcgggt	Protospacer
*****************.********* ****

13. spacer 96.2|7574068|32|CP032698|CRISPRCasFinder matches to CP032698 position: 5326362-5326331, mismatch: 2

gaagcgaccgcggtccgtaggttcgagagggt	CRISPR spacer
gaagcgaccgcggtccgcaggttcgagcgggt	Protospacer
*****************.********* ****

14. spacer 96.2|7574068|32|CP032698|CRISPRCasFinder matches to CP032698 position: 5326419-5326388, mismatch: 2

gaagcgaccgcggtccgtaggttcgagagggt	CRISPR spacer
gaagcgaccgcggtccgcaggttcgagcgggt	Protospacer
*****************.********* ****

15. spacer 96.2|7574068|32|CP032698|CRISPRCasFinder matches to CP032698 position: 5326476-5326445, mismatch: 2

gaagcgaccgcggtccgtaggttcgagagggt	CRISPR spacer
gaagcgaccgcggtccgcaggttcgagcgggt	Protospacer
*****************.********* ****