CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP031554	Pasteurella multocida strain BS168 chromosome, complete genome	4 crisprs	cas1,cas6f,cas7f,cas5f,DEDDh,cas3,csa3,DinG	3	19	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP031554_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031554_1

209135-210002

Unclear

Consensus_repeat	Method
TTTCTAAGCCATCTACACGATGGTGAAC	PILER-CR
TTTCTAAGCCATCTACACGATGGTGAAC	CRISPRCasFinder
TTTCTAAGCCATCTACACGATGGTGAAC	CRT

14 spacers

cas1,cas3-cas2,cas6f,cas7f,cas5f

The CRISPR arrays of CP031554_1

>merge|CP031554|1|209135-210002|PILER-CR,CRISPRCasFinder,CRT
TTTTTAAGCCATCTACACGATGGTGAACTCGCAATATCCGTTAGTTTCTTAGCTTTAACTTTTCTAAGCCATCTACACGATGGTGAACATTTCAAGCTTAGATGTGAAATTCGCACCAACTTTCTAAGCCATCTACACAATGGTGAACATTTCAAGCTTAGATGTGAAATTCGCACCAACTTTCTAAGCCATCTACACGATGGTGAACATTTCAAGCTTAGATGTGAAATTCGCACCAACTTTCTAAGCCATCTACACGATGGTGAACATTTCAAGCTTAGATGTGAAATTCGCACCAACTTTCTAAGCCATCTACACGATGGTGAACGTAGTGAATCTTGCGGATAAACGTAGCTTAAATTTCTAAGCCATCTACACGATGGTGAACTTAATTCATCTGTTCAAGCGCAAGGTGGGCTTTTTCTAAGCCATCTACACGATGGTGAACTTCCAGCGTCGCGCGGTGTTAAATGAGACTTTTTTCTAAGCCATCTACACGATGGTGAACAGCTCCACTTTGATTGCCTCTAACATCGGGTATTTCTAAGCCATCTACACGATGGTGAACTCAAATCTCACGCACTTTCAGCACATGTTGTGTTTCTAAGCCATCTACACGATGGTGAACGATTGTCAGCCGTTAGTTGAACACGTCATTATTTTCTAAGCCATCTACACGATGGTGAACAGGGCATGGATTTTCGGCACTGGAAATCGAATTTTCTAAGCCATCTACACGATGGTGAACTTTTCAATGACCGTTAAATCTTCTAGTGTTTCTTTCTAAGCCATCTACACGATGGTGAACCTGTATTTCTAATAAATCGGTCTTCAGCTAATTTTCTAAGCCATCTACACGATGGTGAAC

>CP031554|1|1|209135-210002|PILER-CR
TTTTTAAGCCATCTACACGATGGTGAAC	TCGCAATATCCGTTAGTTTCTTAGCTTTAACT
TTTCTAAGCCATCTACACGATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACAATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACGATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACGATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACGATGGTGAAC	GTAGTGAATCTTGCGGATAAACGTAGCTTAAA
TTTCTAAGCCATCTACACGATGGTGAAC	TTAATTCATCTGTTCAAGCGCAAGGTGGGCTT
TTTCTAAGCCATCTACACGATGGTGAAC	TTCCAGCGTCGCGCGGTGTTAAATGAGACTTT
TTTCTAAGCCATCTACACGATGGTGAAC	AGCTCCACTTTGATTGCCTCTAACATCGGGTA
TTTCTAAGCCATCTACACGATGGTGAAC	TCAAATCTCACGCACTTTCAGCACATGTTGTG
TTTCTAAGCCATCTACACGATGGTGAAC	GATTGTCAGCCGTTAGTTGAACACGTCATTAT
TTTCTAAGCCATCTACACGATGGTGAAC	AGGGCATGGATTTTCGGCACTGGAAATCGAAT
TTTCTAAGCCATCTACACGATGGTGAAC	TTTTCAATGACCGTTAAATCTTCTAGTGTTTC
TTTCTAAGCCATCTACACGATGGTGAAC	CTGTATTTCTAATAAATCGGTCTTCAGCTAAT
TTTCTAAGCCATCTACACGATGGTGAAC

>CP031554|1|1|209135-210002|CRISPRCasFinder
TTTTTAAGCCATCTACACGATGGTGAAC	TCGCAATATCCGTTAGTTTCTTAGCTTTAACT
TTTCTAAGCCATCTACACGATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACAATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACGATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACGATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACGATGGTGAAC	GTAGTGAATCTTGCGGATAAACGTAGCTTAAA
TTTCTAAGCCATCTACACGATGGTGAAC	TTAATTCATCTGTTCAAGCGCAAGGTGGGCTT
TTTCTAAGCCATCTACACGATGGTGAAC	TTCCAGCGTCGCGCGGTGTTAAATGAGACTTT
TTTCTAAGCCATCTACACGATGGTGAAC	AGCTCCACTTTGATTGCCTCTAACATCGGGTA
TTTCTAAGCCATCTACACGATGGTGAAC	TCAAATCTCACGCACTTTCAGCACATGTTGTG
TTTCTAAGCCATCTACACGATGGTGAAC	GATTGTCAGCCGTTAGTTGAACACGTCATTAT
TTTCTAAGCCATCTACACGATGGTGAAC	AGGGCATGGATTTTCGGCACTGGAAATCGAAT
TTTCTAAGCCATCTACACGATGGTGAAC	TTTTCAATGACCGTTAAATCTTCTAGTGTTTC
TTTCTAAGCCATCTACACGATGGTGAAC	CTGTATTTCTAATAAATCGGTCTTCAGCTAAT
TTTCTAAGCCATCTACACGATGGTGAAC

>CP031554|1|1|209135-210002|CRT
TTTTTAAGCCATCTACACGATGGTGAAC	TCGCAATATCCGTTAGTTTCTTAGCTTTAACT
TTTCTAAGCCATCTACACGATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACAATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACGATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACGATGGTGAAC	ATTTCAAGCTTAGATGTGAAATTCGCACCAAC
TTTCTAAGCCATCTACACGATGGTGAAC	GTAGTGAATCTTGCGGATAAACGTAGCTTAAA
TTTCTAAGCCATCTACACGATGGTGAAC	TTAATTCATCTGTTCAAGCGCAAGGTGGGCTT
TTTCTAAGCCATCTACACGATGGTGAAC	TTCCAGCGTCGCGCGGTGTTAAATGAGACTTT
TTTCTAAGCCATCTACACGATGGTGAAC	AGCTCCACTTTGATTGCCTCTAACATCGGGTA
TTTCTAAGCCATCTACACGATGGTGAAC	TCAAATCTCACGCACTTTCAGCACATGTTGTG
TTTCTAAGCCATCTACACGATGGTGAAC	GATTGTCAGCCGTTAGTTGAACACGTCATTAT
TTTCTAAGCCATCTACACGATGGTGAAC	AGGGCATGGATTTTCGGCACTGGAAATCGAAT
TTTCTAAGCCATCTACACGATGGTGAAC	TTTTCAATGACCGTTAAATCTTCTAGTGTTTC
TTTCTAAGCCATCTACACGATGGTGAAC	CTGTATTTCTAATAAATCGGTCTTCAGCTAAT
TTTCTAAGCCATCTACACGATGGTGAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP031554.1\|AXO02837.1\|199698_200163_-\|Fe-S-cluster-assembly-transcriptional-regulator-IscR	unknown	unknown	gnl\|CDD\|273927
CP031554.1\|AXO02853.1\|223342_224914_+\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|380294
CP031554.1\|AXO02844.1\|210142_210703_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	cas6f	cd09674_cas6f_CAS-I-F	gnl\|CDD\|274202
CP031554.1\|AXO02848.1\|214604_217469_+\|helicase-IV	unknown	unknown	gnl\|CDD\|182930
CP031554.1\|AXO02843.1\|207984_208965_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	cas1	cd09718_cas1_CAS-I-F	gnl\|CDD\|187849
CP031554.1\|AXO02842.1\|204683_208004_-\|type-I-F-CRISPR-associated-helicase-Cas3	cas3-cas2	cas3-cas2-CAS-I-F	gnl\|CDD\|187804
CP031554.1\|AXO02846.1\|211715_212678_-\|type-I-F-CRISPR-associated-protein-Csy2	cas5f	cd09676_cas5f_CAS-I-F	gnl\|CDD\|274204
CP031554.1\|AXO02841.1\|202769_204626_-\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|236842
CP031554.1\|AXO02850.1\|219510_220179_+\|putative-tetracyline-resistance-transcriptional-regulator-TetC	unknown	unknown	gnl\|CDD\|224228
CP031554.1\|AXO02847.1\|212784_214596_+\|hypothetical-protein	unknown	unknown	unknown
CP031554.1\|AXO02835.1\|197818_198205_-\|Fe-S-cluster-assembly-scaffold-IscU	unknown	unknown	gnl\|CDD\|183087
CP031554.1\|AXO02840.1\|202038_202629_-\|hypothetical-protein	unknown	unknown	unknown
CP031554.1\|AXO02839.1\|201171_201975_+\|inositol-1-monophosphatase	unknown	unknown	gnl\|CDD\|236753
CP031554.1\|AXO02836.1\|198436_199651_-\|IscS-subfamily-cysteine-desulfurase	unknown	unknown	gnl\|CDD\|184450
CP031554.1\|AXO02849.1\|217863_219072_+\|IS4-like-element-ISVsa5-family-transposase	unknown	unknown	gnl\|CDD\|376573
CP031554.1\|AXO02852.1\|222671_223289_+\|hypothetical-protein	unknown	unknown	unknown
CP031554.1\|AXO02838.1\|200241_200958_-\|tRNA-(cytosine(32)/uridine(32)-2'-O)-methyltransferase-TrmJ	unknown	unknown	gnl\|CDD\|223639
CP031554.1\|AXO02834.1\|197425_197749_-\|iron-sulfur-cluster-assembly-protein-IscA	unknown	unknown	gnl\|CDD\|213674
CP031554.1\|AXO02845.1\|210705_211713_-\|type-I-F-CRISPR-associated-protein-Csy3	cas7f	cd09677_cas7f_CAS-I-F	gnl\|CDD\|378222
CP031554.1\|AXO02851.1\|220291_221497_-\|tetracycline-efflux-MFS-transporter-Tet(B)	unknown	unknown	gnl\|CDD\|340946

Protein	Function_ID	Function_description	E-value
CP031554.1\|AXO02837.1\|199698_200163_-\|Fe-S-cluster-assembly-transcriptional-regulator-IscR	gnl\|CDD\|273927	TIGR02010, Putative_HTH-type_transcriptional_regulator, iron-sulfur cluster assembly transcription factor IscR. This model describes IscR, an iron-sulfur binding transcription factor of the ISC iron-sulfur cluster assembly system. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Regulatory functions, DNA interactions].	5.78928e-83
CP031554.1\|AXO02853.1\|223342_224914_+\|restriction-endonuclease	gnl\|CDD\|380294	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated BREX (bacteriophage exclusion) type 1 systems. The phage resistance appears not to be through restriction-modification, as phage DNA appears not to get degraded, but it does manage to inhibit phage replication.	7.03455e-36
CP031554.1\|AXO02844.1\|210142_210703_-\|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4	gnl\|CDD\|274202	TIGR02563, conserved_hypothetical_protein, CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2462 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy4, for CRISPR/Cas Subtype Ypest protein 4.	1.09974e-90
CP031554.1\|AXO02848.1\|214604_217469_+\|helicase-IV	gnl\|CDD\|182930	PRK11054, helD, DNA helicase IV; Provisional.	1.92966e-78
CP031554.1\|AXO02843.1\|207984_208965_-\|type-I-F-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187849	cd09718, Cas1_I-F, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	0
CP031554.1\|AXO02842.1\|204683_208004_-\|type-I-F-CRISPR-associated-helicase-Cas3	gnl\|CDD\|187804	cd09673, Cas3_Cas2_I-F, CRISPR/Cas system-associated protein Cas3/Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas3/Cas2 fusion; This protein includes both DEAH and HD motifs for helicase and N-terminal domain corresponding to Cas2 RNAse; signature gene for Type I and subtype I-F.	0
CP031554.1\|AXO02846.1\|211715_212678_-\|type-I-F-CRISPR-associated-protein-Csy2	gnl\|CDD\|274204	TIGR02565, conserved_hypothetical_protein, CRISPR type I-F/YPEST-associated protein Csy2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This protein family, typified by YPO2464 of Yersinia pestis, is a CRISPR-associated (Cas) family strictly associated with the Ypest subtype of CRISPR/Cas locus. This family is designated Csy2, for CRISPR/Cas Subtype Ypest protein 2.	1.19582e-149
CP031554.1\|AXO02841.1\|202769_204626_-\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|236842	PRK11091, PRK11091, aerobic respiration control sensor protein ArcB; Provisional.	0
CP031554.1\|AXO02850.1\|219510_220179_+\|putative-tetracyline-resistance-transcriptional-regulator-TetC	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.43536e-14
CP031554.1\|AXO02835.1\|197818_198205_-\|Fe-S-cluster-assembly-scaffold-IscU	gnl\|CDD\|183087	PRK11325, PRK11325, scaffold protein; Provisional.	1.51567e-94
CP031554.1\|AXO02851.1\|220291_221497_-\|tetracycline-efflux-MFS-transporter-Tet(B)	gnl\|CDD\|340946	cd17388, MFS_TetA, Tetracycline resistance protein TetA and related proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of tetracycline resistance proteins similar to Escherichia coli TetA(A), TetA(B), and TetA(E), which are metal-tetracycline/H(+) antiporters that confer resistance to tetracycline by an active tetracycline efflux, which is an energy-dependent process that decreases the accumulation of the antibiotic in cells. TetA-like tetracycline resistance proteins belongs to the Eukaryotic Solute carrier 46 (SLC46)/Bacterial Tetracycline resistance (TetA) -like (SLC46/TetA-like) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.21806e-178
CP031554.1\|AXO02839.1\|201171_201975_+\|inositol-1-monophosphatase	gnl\|CDD\|236753	PRK10757, PRK10757, inositol-1-monophosphatase.	9.50997e-153
CP031554.1\|AXO02836.1\|198436_199651_-\|IscS-subfamily-cysteine-desulfurase	gnl\|CDD\|184450	PRK14012, PRK14012, IscS subfamily cysteine desulfurase.	0
CP031554.1\|AXO02849.1\|217863_219072_+\|IS4-like-element-ISVsa5-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	7.26216e-11
CP031554.1\|AXO02838.1\|200241_200958_-\|tRNA-(cytosine(32)/uridine(32)-2'-O)-methyltransferase-TrmJ	gnl\|CDD\|223639	COG0565, LasT, rRNA methylase [Translation, ribosomal structure and biogenesis].	3.89077e-117
CP031554.1\|AXO02834.1\|197425_197749_-\|iron-sulfur-cluster-assembly-protein-IscA	gnl\|CDD\|213674	TIGR02011, Protein_yfhF., iron-sulfur cluster assembly protein IscA. This model represents the IscA component of the ISC system for iron-sulfur cluster assembly. The ISC system consists of IscRASU, HscAB and an Isc-specific ferredoxin. IscA previously was believed to act as a scaffold and now is seen as an iron donor protein. This clade is limited to the proteobacteria. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	6.36459e-65
CP031554.1\|AXO02845.1\|210705_211713_-\|type-I-F-CRISPR-associated-protein-Csy3	gnl\|CDD\|378222	pfam09615, Cas_Csy3, CRISPR-associated protein (Cas_Csy3). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a widespread family of prokaryotic direct repeats with spacers of unique sequence between consecutive repeats. This entry, typified by YPO2463 of Yersinia pestis, is a CRISPR-associated (Cas) entry strictly associated with the Ypest subtype of CRISPR/Cas locus. It is designated Csy3, for CRISPR/Cas Subtype Ypest protein 3.	0

>CP031554.1|AXO02843.1|207984_208965_-|type-I-F-CRISPR-associated-endonuclease-Cas1
MRKTPYIPSSDLKTIMHSKRANIYYLEHCRVLLNGGRVEYVTDEGRESLYWNIPIANTSCLLLGSGTSITQAAMRELSKAGVMVGFCSGGGTPLFNGTEAEIGCEFFSPQSEYRPVMYLQQWCKFWFDDEKRLAVAKALQQQRLALLEPIWSKLEWVYSCEKLTALVTQYQHEFAQAAHSQALLAAEGRLTTKLYALANQATMNEPDFKRSERGKSIDLVNQFLDHGNYLAYGLGATACWVLGLPHGLAVLHGKTRRGGLVFDAADIIKDSMILPQAFISAQNGDSEKEFRQACIQNLLRFGALDIIIERLQQLALQGASDEYFAG
>CP031554.1|AXO02842.1|204683_208004_-|type-I-F-CRISPR-associated-helicase-Cas3
MNILLVSQCQKNALTETRRILDQFAERCGDRVWQTAITQAGLETLYKMLRQTARKNTAVACYWTHRKNSAELLWIVGDRRQFNDQGRVPTNRTQRNILRAEEEIAWQDAYSLQILTALSALLHDVGKSSVGFQTKLDKTKNAPRVADSYRHEWISVRLFEAMIEGCQTDQAWLERLANWQVFEETNPTWFSKIIQDRPNENHFSDFAYLPPLARRVIWLITSHHRLPFTHDISRSQDCIKNLRKYAKLTFESLFKAYKPAVGWVSNGAEHPTPQAFWQFQRVATQSQAWQKHMARWAKKALNHPALFSVSENADPFLLLLARLCLMTGDHYYSAQDQNEKLGELNFPLLANTYRENHQPKQRLDEHLIGVCQTAVRFARLLPKFPRELPRIKQHKPFVQLAKDRFAWQNKAVNVARLLQKTSESQGFFGVNMASTGCGKTLANAKMMYALNDSKQGARFTIALGLRVLTLQTGSALKKRLHLSDQDLAVLVGGSAVKKLYALQQEKQNQLAQQGSESAEDWLEDMQVEGATYIESAVENEAVLSFLSKDDKTKKLLYAPIVSCTLDHLISASESVRGGHHIVPILRLLTSDLILDEPDDFAQEDLPALSRLVYLAGLFGSRVLLSSATLTPDFITGLFKAYQAGRKIYNQQKGIVAALPICCAWVDEFQQVQANCGQDEQFIQQHDEFVRKRAENLAKSPVRRQAEILSLPSLKPREGEDLHYGLLADTLLQKAMALHDLHGQTDPHSQKKVSVGLIRFSNIEPMIPLAKALFALQASEKFADYQVHLCCYHSRQLLLLRSYLEEKLDKILDRHTPEQLFQHEEIALPMSQYKAKNHLFIVLGSPVTEVGRDHDYDWAIVDPSSMRSIIQLAGRVWRHRAEKVAEQPNIALLPINWRGLKVRYQQKDVIYHRPGFESHQHKLATHKLDQLISQRDLAHIQATPRIVKPEVLQASTQLADLEHHAIASLLNHPSENLVNLYWDPRYCNYLLANLPLMSEFRKSMAELEVVCVPDEDSHWGFGFYRAQKRDEETLSALPEIQYEPIQQDKHAVVQPWLAAALDTVLSDLAEQLNVVSPEWIAPTYLCASLPQYDGKLDWHYNEVYGFW
>CP031554.1|AXO02841.1|202769_204626_-|hybrid-sensor-histidine-kinase/response-regulator
MKNIKYFTQKYVDWVIRLGRLRFSILGVIVLAILALCTQALLSLFIIGEVYWVDMIRSVVFGLISAPFVIYFFTVLVEKLERSRLGLAKMVENLRKEVSERVLAEKKLSIALDNIEKTSRDKTRLMATISHELRTPLNGIIGLSRILLDEKLTETQQNYLKTIHVSAISLGHIFSDIIDLEKIDARRIELNAKAVELNSFLNDISNVARLLAQQKKLAFQLVTDKNLPTWFMVDYARLSQILWNLIGNAVKFTQEGRITLNVKRVSEYQISFSVSDTGIGIPANELPRVFEMYYQVQSSGHKPLGSGIGLAISQTIAQLMGGDLYATSEMGKGSCFTLMLPVKEVEKPVRVQNQMPSTLNILLVEDIEVNVVVAKSVLEKLGYVVDVAMTGQQAIEKFEQQYYDLLLLDIQLPDMSGFAVAKYLREGYENGQYDFLPPLIALTANVMHDKKEYQAQGMDDVLRKPLSIEELTACLVEYFGHDVSLCLETPTTHQITQDATHFDVKMLSELVEMLGTDFVLKNLALFKETMPEYMQALMTAYSVYQQDESQKADVLSCAHKIKGAAASVGLKRIQQIAAQAQDPEQGEWTENIHDWVQQLAQYWLLDVEALERYLNKSV
>CP031554.1|AXO02840.1|202038_202629_-|hypothetical-protein
MKIFAVLSAFLMPFVVPNTTVNGYKDLRFGMTIEQAKETKLCEDQWHLPADDDWRRVVRGYWVCDKFRFDDGYAVARLRFIGGQLKSIELKMPEYPKYPAELLLHVLEEKYGKTIEVEQRDLIEEDILQGKIRKRRKNESALLDTYQFAKGTVSLTLLTYNGIPQPAEIIYSAPELLLLEKKLEDRPQRRTLLRDL
>CP031554.1|AXO02839.1|201171_201975_+|inositol-1-monophosphatase
MNPMLNIAIRAARKAGNVIAKGYERRDALQTTLKSTNDYVTNIDKASEEAIIEVIRKSYPDHTIITEESGALEGKDSDIQWVIDPLDGTTNFVKGLPHFSVSIAIRVKGRTEVGVVYDPIRNELFTAVRGEGAKINDMRLRVENKRDLAGTVLTTGFPFKQTRLMPMQFAMMNNLIQDCADFRRMGSAALDLCYVAAGRVDGYFEVGVKAWDIAAGDLIVREAGGLVCDFNGGHSYLTSGHLVAAAPRIVKEILNKIQPCLSDEFKK
>CP031554.1|AXO02838.1|200241_200958_-|tRNA-(cytosine(32)/uridine(32)-2'-O)-methyltransferase-TrmJ
MLENIRIVLVETSHSGNIGSAARAMKTMGLNQLYLVAPKQPLDEHAIALSAGAEDVLKQAKIVASFDEAVADCALVIGTSARLRHLQNSLIEPRECGTHAIVYAKQAPVAIVFGRERIGLTNEELLKCRYHLTIPANPDYSSLNLAMAVQLICYELRLAFLSQQAMTESLSTIDNTYPTHTEIEHFFQHTERLYTALGFIQNQGVMPKLRRLYQRVQLEKNELNILRGMLTAVEKRLK
>CP031554.1|AXO02837.1|199698_200163_-|Fe-S-cluster-assembly-transcriptional-regulator-IscR
MKLTSKGRYAVTAILDIALNSNRGPVSLSDISERQHISLSYLEQLFAKLRRHGLVKSVRGPGGGYQLGLPANRISVGMVINAVNENIDVTRCLGRGDCQEGTECLTHSLWKELSLRIEAFLNEITLEELVEKNRQKRATIEFRGDFDNLIILDN
>CP031554.1|AXO02836.1|198436_199651_-|IscS-subfamily-cysteine-desulfurase
MKLPIYLDYAATCPVDERVAKKMMEYLTVEGNFGNPASRSHKFGWQAEEAVDVARNHIADLIGADSREIVFTSGATESDNLAIKGAAHFYQSKGKHIITCKTEHKAVLDTCRQLEREGFEVTYLNPKSDGLIDLEELKNAMRDDTILVSIMHVNNEIGVIQDIAAIGELCRARKILFHVDATQSVGKLPINLAELKVDLMSMSSHKLYGPKGIGALYVSRKPRVRLEAIIHGGGHERGMRSGTLPVHQIVGMGEAYRICKEEMASEMPRLKALRDRLYNGLKDIEETYVNGSMEHRLDSNLNISFNYVEGESLMMALRDIAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFTLGRYTTEEEIDYTIELVKNAVAKLRELSPLWDMFKEGIDLNTIEWTHH
>CP031554.1|AXO02835.1|197818_198205_-|Fe-S-cluster-assembly-scaffold-IscU
MAYSNKVIDHYENPRNVGSLDKKDANVGTGMVGAPACGDVMQLQIKVSEEGIIEDAKFKTYGCGSAIASSSLITEWVKGKSLDEAQAIKNSQIAEELELPPVKVHCSILAEDAIKAAIADYKAKKEAK
>CP031554.1|AXO02834.1|197425_197749_-|iron-sulfur-cluster-assembly-protein-IscA
MGISLTETAADRVRTFLANRGKGIGLRLGIKTSGCSGLAYVLEFVDELNPEDQVFEQHGVKIIVDAKSLVYLDGTELDFAKEGLNEGFKFNNPNVKDQCGCGESFHV
>CP031554.1|AXO02844.1|210142_210703_-|type-I-F-CRISPR-associated-endoribonuclease-Cas6/Csy4
MTTHYIELKAIPQMDMLQSEVIGHCMQILHQFLPHFEGRVGVAFPAYGLGRTLGGIVRLFANQEDCNQLHQQLLRSGLSDYALISEVSKTPLSTECRSYSRVHRKGQSAIRRTEKRLKSQGRWDESIRADMQQRQQNVAFFPHCHLKSASTGQRFILAVKENRMPQSCVGVFNAYGLSNSATVPHF
>CP031554.1|AXO02845.1|210705_211713_-|type-I-F-CRISPR-associated-protein-Csy3
MSKLSTPSVLAFERNLDISDAIFAQKDSKNDKDAPVPLRIREKSVRGTISNRLKNTITNDPAKLDAETEKANLQRVDVATLDDDKDTLVATFSVKVLPFTGRPNVCNDQDYQHQVMTTVAQYLSEQGMDELAKRYATNIANARWLWRNRMGAEKIKIEVTCGENTLHFDDAKQFSLNHFDHQDDKIHQIAKEIKQGLLGEKFVILYVTAYANMGYGQEVYPSQELVLDNSTNNRKSKILYEINQKAGMHSQKVGNAIRTIDTWYAEEVAFPIAAEPYGAVTTLGTAFRQPKTKKNDFYTLFDNWLLKGEVPPVEQQHYVMSVLIRGGVFGASGKE
>CP031554.1|AXO02846.1|211715_212678_-|type-I-F-CRISPR-associated-protein-Csy2
MLFDHIKVQSANAISGPLSYGFPALTGLTGAMHALNRKLTHHPVQFGGVMVACHDYELQTYQNSAFSDRTFKQTRNPIKRNGETASIIEEGKIHLDLSLVVEVHVQDDRVFEALTDKTSQASQDFLQTCKNLLWQQRIAGGSVLEIGNVQLFNLEEDQDIPLALMPAFVLMDAKQELTNITEELKTGLRIGQLDEEGNVQKSCLPSCPDATALDALLEMATVHHIPEHANATASAWQTYSVKKGRGWLVPLPVGYQAISPLFAPGQLQHCRTQQYPSQYVETLYSLGKWVFPLSLPENLSQCFWRYTALQNNLYLISQGE
>CP031554.1|AXO02847.1|212784_214596_+|hypothetical-protein
MFYLNNDNFKREPYRGYCPRHLEKLFTKPHLDIRGNGYYYPDNEYVVAWYESDFIFKSRKAQAHAKVKLVNLTCSKYTGKNSAEYLSVLYISVPLNYLHYFTIGSIWKGGVAKEQFAFEEFYITVEAENQDGKRENLSIVSFGESKENGLEKPFDYTIYTISTEYHNYGDDLNRLLSISYQNQKFIIHPLHIFMMHYGYSTDIKRILATYPFDEVRERLFIDKVVENLDVERYVVLPKYFVKKDAIFLYHLKYDEETTGIRVKNLVSQFRLNVRNQKHPIEIGFWHTQKVELKIRGIRLGNAVLCAEIIGLNQPEGEDITLVLSQSKREKSGNKTEEQNNEVNNVPITRVYTREPELDELPLTDNSPDNRTVEYNNRQFELLGRQRQIRALKKAREESNQKMKALTPDEIDSLGVGESDGRNGKVGLAFCFLDDTPVGKSSKLYKLWQHAKAVAEWNHGEAHWYTPNLGFRNDDELLPVSLETNKCFDYPEIAIIICLQIYGETFFLIDFSMKQRDISIRGLGYKPDPNEDFLYESDMSKSELSELLSAVHHHEHLPKEYIEKKNKEKTKLTTFNHSEAESSNWAYNAVQKLTSRAITKPTYF
>CP031554.1|AXO02848.1|214604_217469_+|helicase-IV
MNAEQRVIVTPTFWGKFFGKIKSVELQQNKVIVTDKKNNITEHDLGKTFDFPAIQKSFFGTKLFFKDDSTEVVLSKLAKKQTDSLLLEIEKVVASNIKVKVKEGFQHFANLAENQYLRDSDIPTLNDRVRLSVLSYGDNKEHFQKYFDESLVKKIQYISSLFPVNAINAQTIRKEYEQHVLNHRKHFFDVIESNPLTEQQRLSVIRNNDINMVLAAAGTGKTSVMVAKALDLIDSGACKSEDILILAYNRDAATELSERLQERAREANLDLENSPSISTFHALGRRIIKECGKSVHLSKFAEDPMKLDRWFNKWLEDYIKEDPDNLAKFIQLAYQPIDPFQFKTKEEYDRYVNDNDYRTLQGERVRGYQELLIANWLFSHSVEYEYEPRYVSKRRIEIGFDYKPDFSLGDGVYLEHFGIDRQGRTRADINAQEYNANIQRKRELHAEHNTTLLETYHYNWVENTLYKRLEQLMNEQFIPLKPKSQQEILDALNESGIFKENKNRYLKCLQAIRTERLDYQQILKRLTDAKIVYAKEYATLLMRIHDAYVKELRSANEIDFDDMILLATQLVKTGEFKPKWKHILVDEFQDISMARLELLKEIYTKGPRPIWTVVGDDWQSIYRFSGGKLEVTTRFNDMVGSHTLSKLEKTYRYNNSIADTAGQFIMQNPEQYQKNVVTHTKVADSCVHLYDSHVVKDEKSEANISLKASAILKLIRQKAPEATVAILARYRYLLEDAKSVIKDKNVKFWTFHGSKGLEADYCILLGFFQGKVGFPNQNKEEAVVEALLPMLDSFPHSEERRLFYVALTRAKKESYLIADANAPSEFINELLSPKYKIDIVSKRFQERYRTIFKCNECSTGYFVMKQGKFGQFYSCTSGEVCRSSPRICEKCGSPSVDTASMSICQNPNCQNSFPICDKCGRPMRLREGKFGKFWGCSGYGIKDDPCSNTRKYFI
>CP031554.1|AXO02849.1|217863_219072_+|IS4-like-element-ISVsa5-family-transposase
MCELDILHDSLYQFCPELHLKRLNSLTLACHALLDCKTLTLTELGRNLPTKARTKHNIKRIDRLLGNRHLHKERLAVYRWHASFICSGNTMPIVLVDWSDIREQKRLMVLRASVALHGRSVTLYEKAFPLSEQCSKKAHDQFLADLASILPSNTTPLIVSDAGFKVPWYKSVEKLGWYWLSRVRGKVQYADLGAENWKPISNLHDMSSSHSKTLGYKRLTKSNPISCQILLYKSRSKGRKNQRSTRTHCHHPSPKIYSASAKEPWVLATNLPVEIRTPKQLVNIYSKRMQIEETFRDLKSPAYGLGLRHSRTSSSERFDIMLLIALMLQLTCWLAGVHAQKQGWDKHFQANTVRNRNVLSTVRLGMEVLRHSGYTITREDLLVAATLLAQNLFTHGYALGKL
>CP031554.1|AXO02850.1|219510_220179_+|putative-tetracyline-resistance-transcriptional-regulator-TetC
MFLRLSRPHHHDTINILTVCYFKSIMENKNHQQENFKSTYQSLVNSARILFVEKGYQAVSIDEISGKALVTKGAFYHHFKNKKQLLSACYKQQLIMIDAYITTKTDLTNGWSALESIFEHYLDYIIDNNKNLIPIQEVMPIIGWNELEKISLEYITGKVNAIVSKLIQENQLKAYDDDVLKNLLNGWFMHIAIHAKNLKELADKKGQFIAIYRGFLLSLKDK
>CP031554.1|AXO02851.1|220291_221497_-|tetracycline-efflux-MFS-transporter-Tet(B)
MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFGVLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRLLSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSPFFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYFSAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKTAVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGALQGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQAQGSKQETSA
>CP031554.1|AXO02852.1|222671_223289_+|hypothetical-protein
MTFSRRIGELWEPFCKLAFKYSTKDLLLVEPLDFNQIKEDIKGNAINFIYKLPISFEDKNELIRLYETPWNLMGSGGIKLDLDLHFSQGNCYHNCDFKSGFSSNEKGNTNRLLLVGSIYNSLNQYMRNIIFVRQPEDQNNHYLQKLKHSGYWEVYCADDAYSVMAEFTGFNLKSWLENNADWANDMEQDFRRHLERNNLISYLTW
>CP031554.1|AXO02853.1|223342_224914_+|restriction-endonuclease
MKDIYCSFYTNSDLITNYMVHKIKLCNNDKVLEPSAGEGVFIDEILKSNIHLHIDALDINPEAVRVLNKKYSSYSSIKVRETDTLLDNELDLYDTSELWIKETDTLIDNEIDYFAKTGGYYDKVIGNPPYGAWQDHEKRSTLKKKYLGHYVKETYTLFLLRCLSVLKPKGLLSFIIPDTFMFLNMHSNLRKTLLTNAKIKEVLIFPSKFFPGVNFGYSNLSIITLEKCCKGDYQENEITIIKGLKNINELELLSKGLVDQIPNLNKLKIKQNEILNNPDCRFILTESEDKDMLINSKVKLGDIASVVTGFYTGNNVEFIKVLDKNVKGSKGYKIIKENEIFNSNSLEGIENVNYGYIPYIKRASAGKYFRGKDEWFVRWDKDAIAYYQTNKKSRFQNTTYYFKTGIGIPMVKSKSIKAFLMEDRVFDQSIVGLFPYEESKTLYILALMNSSVMNKYIHLINPTANNSANYIKQLPYIEPTESQMNIINKMVSELITLQKLDKLDKAEKIHDEVDKIISEIYSS

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Crispr_ID: CP031554_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031554_2

231284-231436

Unclear

Consensus_repeat	Method
TTATGACATTTATTTCTGGTTTTTA	CRISPRCasFinder

2 spacers

The CRISPR arrays of CP031554_2

>merge|CP031554|2|231284-231436|CRISPRCasFinder
ATTTGACACCTATTTCTTGTTTTCTAAATAATCTGACAGCTATTTCTAGTTTTTATGACATTTATTTCTGGTTTTTATGTCGTAAAAAATAGGATAAACCCTTATCCTTTCGTTGAATGAATAGCTAATTATGACATTTATTTCTAGTTTTTA

>CP031554|2|2|231284-231436|CRISPRCasFinder
ATTTGACACCTATTTCTTGTTTTCT	AAATAATCTGACAGCTATTTCTAGTTT
TTATGACATTTATTTCTGGTTTTTA	TGTCGTAAAAAATAGGATAAACCCTTATCCTTTCGTTGAATGAATAGCTAA
TTATGACATTTATTTCTAGTTTTTA

Protein	Signature genes	Signature genes Name	Protein_function
CP031554.1\|AXO02868.1\|251053_251992_-\|bifunctional-biotin-operon-repressor/biotin--[acetyl-CoA-carboxylase]-ligase	unknown	unknown	gnl\|CDD\|237010
CP031554.1\|AXO02853.1\|223342_224914_+\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|380294
CP031554.1\|AXO04816.1\|243991_244255_+\|hypothetical-protein	unknown	unknown	unknown
CP031554.1\|AXO02859.1\|230616_231279_-\|heteromeric-transposase-endonuclease-subunit-TnsA	unknown	unknown	gnl\|CDD\|378037
CP031554.1\|AXO02857.1\|227811_228699_-\|transposase	unknown	unknown	gnl\|CDD\|377533
CP031554.1\|AXO02864.1\|238959_241863_-\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	unknown	unknown	gnl\|CDD\|273808
CP031554.1\|AXO02850.1\|219510_220179_+\|putative-tetracyline-resistance-transcriptional-regulator-TetC	unknown	unknown	gnl\|CDD\|224228
CP031554.1\|AXO02855.1\|225317_226775_-\|hypothetical-protein	unknown	unknown	unknown
CP031554.1\|AXO02862.1\|237272_238385_+\|iron-sulfur-cluster-carrier-protein-ApbC	unknown	unknown	gnl\|CDD\|183270
CP031554.1\|AXO02863.1\|238523_238793_-\|30S-ribosomal-protein-S15	unknown	unknown	gnl\|CDD\|180170
CP031554.1\|AXO02860.1\|232749_234909_-\|bifunctional-23S-rRNA-(guanine(2069)-N(7))-methyltransferase-RlmK/23S-rRNA-(guanine(2445)-N(2))-methyltransferase-RlmL	unknown	unknown	gnl\|CDD\|236981
CP031554.1\|AXO02852.1\|222671_223289_+\|hypothetical-protein	unknown	unknown	unknown
CP031554.1\|AXO02854.1\|224975_225200_-\|tRNA-delta(2)-isopentenylpyrophosphate-transferase	unknown	unknown	unknown
CP031554.1\|AXO02858.1\|228698_230627_-\|transposase	unknown	unknown	gnl\|CDD\|366234
CP031554.1\|AXO02856.1\|226735_227854_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377670
CP031554.1\|AXO02851.1\|220291_221497_-\|tetracycline-efflux-MFS-transporter-Tet(B)	unknown	unknown	gnl\|CDD\|340946
CP031554.1\|AXO02866.1\|242435_242927_-\|heme-utilization-cystosolic-carrier-protein-HutX	unknown	unknown	gnl\|CDD\|226244
CP031554.1\|AXO02865.1\|241904_242420_-\|heme-utilization-protein-HutZ	unknown	unknown	gnl\|CDD\|200361
CP031554.1\|AXO02867.1\|250145_250991_+\|hypothetical-protein	unknown	unknown	unknown
CP031554.1\|AXO02861.1\|235042_237091_-\|methionine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234655

Protein	Function_ID	Function_description	E-value
CP031554.1\|AXO02853.1\|223342_224914_+\|restriction-endonuclease	gnl\|CDD\|380294	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated BREX (bacteriophage exclusion) type 1 systems. The phage resistance appears not to be through restriction-modification, as phage DNA appears not to get degraded, but it does manage to inhibit phage replication.	7.03455e-36
CP031554.1\|AXO02859.1\|230616_231279_-\|heteromeric-transposase-endonuclease-subunit-TnsA	gnl\|CDD\|378037	pfam08722, Tn7_Tnp_TnsA_N, TnsA endonuclease N terminal. The Tn7 transposase is composed of proteins TnsA and TnsB. DNA breakage at the 5' end of the transposon is carried out by TnsA, and breakage and joining at the 3' end is carried out by TnsB. The N terminal domain of TnsA is catalytic.	7.90649e-18
CP031554.1\|AXO02857.1\|227811_228699_-\|transposase	gnl\|CDD\|377533	pfam05621, TniB, Bacterial TniB protein. This family consists of several bacterial TniB NTP-binding proteins. TniB is a probable ATP-binding protein which is involved in Tn5053 mercury resistance transposition.	2.17903e-97
CP031554.1\|AXO02864.1\|238959_241863_-\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	gnl\|CDD\|273808	TIGR01786, hemoglobin-haptoglobin-binding_protein, TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein. This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	1.64668e-109
CP031554.1\|AXO02850.1\|219510_220179_+\|putative-tetracyline-resistance-transcriptional-regulator-TetC	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.43536e-14
CP031554.1\|AXO02862.1\|237272_238385_+\|iron-sulfur-cluster-carrier-protein-ApbC	gnl\|CDD\|183270	PRK11670, PRK11670, iron-sulfur cluster carrier protein ApbC.	0
CP031554.1\|AXO02863.1\|238523_238793_-\|30S-ribosomal-protein-S15	gnl\|CDD\|180170	PRK05626, rpsO, 30S ribosomal protein S15; Reviewed.	3.85836e-50
CP031554.1\|AXO02860.1\|232749_234909_-\|bifunctional-23S-rRNA-(guanine(2069)-N(7))-methyltransferase-RlmK/23S-rRNA-(guanine(2445)-N(2))-methyltransferase-RlmL	gnl\|CDD\|236981	PRK11783, rlmL, bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL.	0
CP031554.1\|AXO02868.1\|251053_251992_-\|bifunctional-biotin-operon-repressor/biotin--[acetyl-CoA-carboxylase]-ligase	gnl\|CDD\|237010	PRK11886, PRK11886, bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA.	2.13711e-144
CP031554.1\|AXO02858.1\|228698_230627_-\|transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.85711e-13
CP031554.1\|AXO02856.1\|226735_227854_-\|hypothetical-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.8373e-17
CP031554.1\|AXO02851.1\|220291_221497_-\|tetracycline-efflux-MFS-transporter-Tet(B)	gnl\|CDD\|340946	cd17388, MFS_TetA, Tetracycline resistance protein TetA and related proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of tetracycline resistance proteins similar to Escherichia coli TetA(A), TetA(B), and TetA(E), which are metal-tetracycline/H(+) antiporters that confer resistance to tetracycline by an active tetracycline efflux, which is an energy-dependent process that decreases the accumulation of the antibiotic in cells. TetA-like tetracycline resistance proteins belongs to the Eukaryotic Solute carrier 46 (SLC46)/Bacterial Tetracycline resistance (TetA) -like (SLC46/TetA-like) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.21806e-178
CP031554.1\|AXO02866.1\|242435_242927_-\|heme-utilization-cystosolic-carrier-protein-HutX	gnl\|CDD\|226244	COG3721, HugX, Putative heme iron utilization protein [Inorganic ion transport and metabolism].	3.04731e-79
CP031554.1\|AXO02865.1\|241904_242420_-\|heme-utilization-protein-HutZ	gnl\|CDD\|200361	TIGR04110, hypothetical_protein_VSWAT3_12502, heme utilization protein HutZ. Members of this family are heme utilization proteins, typically designated HutZ. They are members of the PPOX family (pfam01243) and, except for the lack of an N-terminal extension, are closely related to one form of heme oxidase (1.14.99.3), HugZ (TIGR04109). Members typically are found in a three-gene operon with radical SAM enzyme HutW and a protein of unknown function, HutX.	1.59144e-95
CP031554.1\|AXO02861.1\|235042_237091_-\|methionine--tRNA-ligase	gnl\|CDD\|234655	PRK00133, metG, methionyl-tRNA synthetase; Reviewed.	0

>CP031554.1|AXO02859.1|230616_231279_-|heteromeric-transposase-endonuclease-subunit-TnsA
MRKTHSFQQVRKIKPTWMSVSGHIPFRNGVSIPYESTLERDFLMYFTYLPSVDEIVSQPTTLPFVKNGITYTYTPDFFLSFTDGRKPMLIEVKPKAKWQKHWKEWKEKWKAAIRFCQENGYVFHVYDEDRIRHLALFNLNYVQRYKRIQHEQEDIDVILAQVKLMGNTTIDYLLSRFFAGSLYRMKGLQIIYHLLATKQLHCNWFLPLNEFTEVWGNNDE
>CP031554.1|AXO02858.1|228698_230627_-|transposase
MMSNSGFTEKRYHHRLDRGRIILQKGNIYLNREDGEQYELVDYMDEPSQLLVRNLNTRTTKVVSIHQLENFKMNERTDLSVDLTAISNEYWEKAQQKYEAIKPLLGMDQHRPYAVKARAEDVGVNPRTLYRWLQAYNSIGSIAGLVDQKRGWQQGNSRLTPEQDKLIVQVINEFYLHKQRPTTEQTIREIRRRCKIEKVESPSKETIRIRILHISEEERLRKRGQREKARNKFKPKPNSFPDADYPLSVVQIDHTPVDLIIVDSKYRKPIGRPFLTVAIDIYSRMIVGYYLSLDAPSVTSVAMCIARGILPKERLLLDLGLQGSEWNAFGYPVKVHVDNGPDFQALDLSKSCFAHGIHLEFRPMGRPEYGGHIERVIGTFMKEVHSLAGTTFSNIKERDSYDSEKEAIMTLDEFEKWLVHYIVNVYHKRVHSALGISPEQKWKIGIFGDENEVGCGYPQLPVDEQTLLLDFLPSITRTIQHNGVTIDGLRYYDVALNMYISDSDESGKSKEFLFRRDPRNISKIWFYDPKLKRYFPIPFANQAMPEMSIWEYREVRSRIANKGDKYINEQQVLDGLTEMREMVAESAQRTKKARRQAERQKMHKASKPIIETKVETNAVVPVVVTSNLLALDDESLSFGEVD
>CP031554.1|AXO02857.1|227811_228699_-|transposase
MQYEHVHEKFRHLVTADNQERIAFLDEPRWLGYGVAKDIMDNLVSLMNKPKRPRMLNLLIVGDSNNGKTTLIRRFFDLYGQAYIDSDSNAIYPILLAEAPPSANEKELYISLLERFYVPYKPTDTIAKLRYQTIHLFREFRVKMLIIDEFHSLLVGTPRLQRQVMNAIKMLCNELQIPIVGVGTRDAIRVLHTDPQHASRFDVAELPTWKLDKDFQKLLFQFQGILPLKKCSNLQSPELATKIHTISGGNLGNVHRLLTACAVEAITSGTEQITLDIIEKNSWVQPTQGFRKIIG
>CP031554.1|AXO02856.1|226735_227854_-|hypothetical-protein
MGTTNAGLPKNYRIKSGVIKTPLYSNESISSWLIRSALDCGTEPITFTGFYWNEWRLWTYDLDRGFEPISQHIYADINELSLNQQVNLVNHSLYSVLRPINGKNTLIKGQAKWVLSRGSRNRSFRVGQSYCPCCLEETPYLRNEWRFAWHFGCLKHKVLFESKCSCCGGLYQPHLLSAEKRQLNYCHQCGEKLQVITTPLNEVEIATMETLDNVFTTNSGECFGKCVDSQVYFAILRYFINFTRRAAIAKSTHSFSRFVEQCGISQVEICQTKTALAFEQLPVEERKNLLVNAGKILKLSSKDFIQAIKQSGITQKAFAFERYPTELDNLFKYAIEGKTTSRKTIINKPKTDSVLSLNRQWERLKRQLQIAV
>CP031554.1|AXO02855.1|225317_226775_-|hypothetical-protein
MGTTKTTITNCSMKITKIRSQNSCSICGKTPVTRKFREEYYCANCYAQWFKKKTCKSCGQLTRIHREGELCLECEKLTDCVRCGKTSGTFEIGMISRYGAVCSSCTRYFREEIECSECGKMTRDRYRSPVTNESVCLQCYRRYTFATCKNCRRYRKVHNQEKQLCKKCDEKLLSTCPKCKGEMPSGYGNVCPDCARRSLLFNMIRLNGHILRNKAVKTAYKKFIFWYMRKCGISVALHKGADFMRFFIDCDEIWQQIPDYAELVTHFKPNGLRANLTVLRWLLDTNQIIVDEALKDDLAELERIQALFNKLKESVPCIASYYQKLQRRCDEGKTSLKSVRLALQPAIDLISTNEVTDYPTQDQLNQYLVKKSGQTAAITGFINHLKSEYHRELEIDRKLIQQIKTKQLKKHCSQRLIELYKKSELTDNEQMELIYVVLYSLHSVEIKKPKQDKILLLDGVAYYRSEDRDYFLPQDIYQRINPQFS
>CP031554.1|AXO02854.1|224975_225200_-|tRNA-delta(2)-isopentenylpyrophosphate-transferase
MNSTNNKSTLSLKQQFKLWLEQEQKDGDMIILVGIPDILKRFDRRLAIIKGNQLEKRYLREWREAFRIDRKLFN
>CP031554.1|AXO02853.1|223342_224914_+|restriction-endonuclease
MKDIYCSFYTNSDLITNYMVHKIKLCNNDKVLEPSAGEGVFIDEILKSNIHLHIDALDINPEAVRVLNKKYSSYSSIKVRETDTLLDNELDLYDTSELWIKETDTLIDNEIDYFAKTGGYYDKVIGNPPYGAWQDHEKRSTLKKKYLGHYVKETYTLFLLRCLSVLKPKGLLSFIIPDTFMFLNMHSNLRKTLLTNAKIKEVLIFPSKFFPGVNFGYSNLSIITLEKCCKGDYQENEITIIKGLKNINELELLSKGLVDQIPNLNKLKIKQNEILNNPDCRFILTESEDKDMLINSKVKLGDIASVVTGFYTGNNVEFIKVLDKNVKGSKGYKIIKENEIFNSNSLEGIENVNYGYIPYIKRASAGKYFRGKDEWFVRWDKDAIAYYQTNKKSRFQNTTYYFKTGIGIPMVKSKSIKAFLMEDRVFDQSIVGLFPYEESKTLYILALMNSSVMNKYIHLINPTANNSANYIKQLPYIEPTESQMNIINKMVSELITLQKLDKLDKAEKIHDEVDKIISEIYSS
>CP031554.1|AXO02852.1|222671_223289_+|hypothetical-protein
MTFSRRIGELWEPFCKLAFKYSTKDLLLVEPLDFNQIKEDIKGNAINFIYKLPISFEDKNELIRLYETPWNLMGSGGIKLDLDLHFSQGNCYHNCDFKSGFSSNEKGNTNRLLLVGSIYNSLNQYMRNIIFVRQPEDQNNHYLQKLKHSGYWEVYCADDAYSVMAEFTGFNLKSWLENNADWANDMEQDFRRHLERNNLISYLTW
>CP031554.1|AXO02851.1|220291_221497_-|tetracycline-efflux-MFS-transporter-Tet(B)
MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFGVLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRLLSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSPFFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYFSAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKTAVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGALQGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQAQGSKQETSA
>CP031554.1|AXO02850.1|219510_220179_+|putative-tetracyline-resistance-transcriptional-regulator-TetC
MFLRLSRPHHHDTINILTVCYFKSIMENKNHQQENFKSTYQSLVNSARILFVEKGYQAVSIDEISGKALVTKGAFYHHFKNKKQLLSACYKQQLIMIDAYITTKTDLTNGWSALESIFEHYLDYIIDNNKNLIPIQEVMPIIGWNELEKISLEYITGKVNAIVSKLIQENQLKAYDDDVLKNLLNGWFMHIAIHAKNLKELADKKGQFIAIYRGFLLSLKDK
>CP031554.1|AXO02860.1|232749_234909_-|bifunctional-23S-rRNA-(guanine(2069)-N(7))-methyltransferase-RlmK/23S-rRNA-(guanine(2445)-N(2))-methyltransferase-RlmL
MKQLFATTARGFEELLKVELTDLGAMDCQITQGGVHFHADEETQYRVLLWTRLASRILLPIVTCKVYSDLDLYSAVVGQNWLDYFDEKAHFMVDFNGTNREIRHTQFGAMRVKDGIVDYFERVGKPRPNVDKSQPDIRIHAYLNREELVISLDLSGDALHMRGYREDTGKAPLRETLAAAIVLRSGWQLGTPLVDPMCGSGTLLIEAAQMQANIAPQLHRLHWGFDFWKGHNQQAWDKVKGEAIELAEQTFNQNQKANFYGCDLDHRVLQKAKRNAQNAGVAHLIQWRQGDVAALKNPFVEAKGTVICNPPYGERLGTTPALIALYSVFGQRLKQQFADWNVSIFSGEPALLDCLRLRSHRQFKAKNGPLDCVQKNYHISARATASDENTQNLPEIDRTLSATQVAVDFANRLQKNSKKIEKWARQQGINAYRLYDADLPEYNLAVDRYDDHIVVQEYAAPKNIDENKARQRLLDAVTATLQVTGVETNKLILKVRQKQKGTNQYEKLANKGDYFYVNEYGAKLWVNLTDYLDTGLFLDHRLTRKMLGKMAKGKDVLNLFAYTGSATVHMALGGAKSTTTVDMSNTYLNWAEQNLLLNDLEGKQHKLIQADCLQWLARCDRQFDLIFVDPPTFSNSKRMEDSWDVQRDHIKLMTQLKRILRPNGTIVFSNNKRGFKMDVEGLETLGLSAVDITAKTLPLDFERNKQIHNCWVVRLKADL
>CP031554.1|AXO02861.1|235042_237091_-|methionine--tRNA-ligase
MANSARNILVTCALPYANGAIHLGHLLEHIQADIWVRFQRMRGHKVHFICADDAHGTPIMLNADKLGITPEALIARSKADHVADFEGFNISYDNYHSTHSPENEALTAEMYKKLRANGFIKSRTISQLFDPEKGMFLPDRFVKGTCPKCKAEDQYGDNCEVCSSTYSPTELINPRSVVSGATPVLKESEHFFFDLPAFEGMLKAWIKSGSLQPEIANKMQEWFESGLQQWDISRDAPYFGFKIPDTEDKYFYVWLDAPIGYMASFKNLCDKTGLNFDDFWKKDSSAELYHFIGKDIVYFHSLFWPAMLDGCDLRKPTNVFAHGYVTVNGVKMSKSRGTFIQASTYLRHLAPEYLRYYYAAKLNNRIEDLDLNLEDFVQRLNADVVNKFVNLASRSAGFITKRFDGKLSAEIAEPELLAEFVEKAAQIATYYEEREFGKVVREVMQLADKANKYIDDKAPWVMAKEEGREAELQAVCSMALQLFRVLAIYLKPVIPQIIARAEAFLQDELTWESLNRPLLNHAILPFKALAQRLDLKQIEAIVNETKEQFVAQQALEQKNSAKAEPASQVEPIAETISIEDFAKLDLRVAKVMKCEAVPESNKLLRFELDLGDHTRQVFSGIKEAYNNPAELEGRFVVVIANLAPRKMRFGVSEGMILSAGTGGDDLFLLNADQGVKPGMQVK
>CP031554.1|AXO02862.1|237272_238385_+|iron-sulfur-cluster-carrier-protein-ApbC
MGILFSDSLTDSQKQAIQNTFQQFQHPSLQKDLVSLNAIKKIEKGGETLRIEISMPFAWNTAFEQLKSALSTELLTLAECKDIKWQLNYQIATLKRANSHPAVKGVKNIIAVTSGKGGVGKSTISVNLALALQRQGARVGILDADIYGPSIPHMLGVADQRPTSPDNQHITPIQAHHIFANSIGFLMEPDNATIWRGPMASSALSQLLQETLWPDLDYLVIDMPPGTGDIQLTLSQQIPVTGAVVVTTPQDIALLDAIKGVAMFERVSVPVLGIIENMSMHICSNCGHQETIFGTGGAERIAQKYNVKVLGQQALHIRLREDLDKGIPTVVAAPESDIAQSFMQLAEKVATELYWQGSVIPSEIMFKEVK
>CP031554.1|AXO02863.1|238523_238793_-|30S-ribosomal-protein-S15
MSLSTEKKAAIVAEFGRDAKDTGSSEVQIALLTAQINHLQSHFATHKKDHHGRRGLLRMVSRRRKLLDYLKRTNLELYTSTIARLGLRR
>CP031554.1|AXO02864.1|238959_241863_-|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor
MRTTTIKFSAITLALLSYCGTILADSHQEATELDTITVSSQQDEMNIKEKKIGETVKTASQLKRQQVQDSRDLVRYETGVTVVEAGRFGSSGYAIRGVDENRVAITVDGLHQAETLSSQGFKELFEGYGNFNNTRNSVEIETLKVAKIAKGADSVKVGSGSLGGAVLFETKDARDFLTEKDWHIGYKAGYSTADNQGLNAVTLAGRYQMFDALIMHSKRHGHELENYDYKNGRDIQGKEREKADPYTITKESTLVKFSFSPTENHRFTVASDTYLQHSRGHDLSYNLVATTHIQLDEKESRHANDLTKRKNVSFTYENYTVTPFWDTLKLSYSQQRITTRARTEDYCDGNELCDSYKNPLGLQFKDGQILDPAGNKIKLQGSGLSTQIVDENGKPFPTTTGTNNAAFSNNLRLRPTGFWLDCSVFDCNKPFTVYNISNGTYQAREVLLSEEITVDGKLYKTAKEEGGLPNYLILPNSKGYLPYDYKERDLNTNTKQINLDLTKTFLTFNIENNLSYGGVYSRIEKEMINKAGYEGRNPTWWADRILGQSSYCGYNALKCPKHEPLTSFLIPVEATTQSLYFANILKVHNMISIDLGYRYDHIKYNPEYTPGVTPKIPDDMVKGLFIPMPKEPQLKDFYYNYAKFGEAYKKWKEYLPKNAEENIAYIAQDKTFKKHSYSLGATFDPLNFLRVQVKYSKGFRAPTSDELYFTFKHPDFTILPNPVLKPEEAKNQEIALTVHDNWGFVSTSVFQTKYRHFIDLAYLGSRNLSNSVGGQAQARDFQVYQNVNVDNAKVKGLEINARLNLGYFWHVLDGFNTSYKFTYQRGRLDGDRPMNAIQPKASVFGLGYDHKENKFGADLYITRVSEKKAKDTYNMFYKEQGYKDSAVRWRSDDYTLVDAVGYIKPIKNLTLQFGVYNLTDRKYLTWESARSIKPFGTSNLINQKTGAGINRFYSPGRNFKLSAEITF
>CP031554.1|AXO02865.1|241904_242420_-|heme-utilization-protein-HutZ
MTTNRQEVLQNRLGPEIQELKAQCKTVMLATVGEDGNPNVSYAPFAINNGEYQVFISTIARHARNLQEVPKVSLMLIEDESQSRQIFARRRLSFDAVARVVERESEECHSGVEALKARHGALMDELSRMKDFHLFSFKPSQGLFVKGFGQAFQVSNDDLVSFVHLVEGHQE
>CP031554.1|AXO02866.1|242435_242927_-|heme-utilization-cystosolic-carrier-protein-HutX
MMLKAQIADYITQNPLAITLDMASHFGKPEGEILCALPDEFVRVFPAERAEEVLAEISSWGIFTTIIEKEGSIFEIKDRFPTGMVGRGYYNLNMKDEEGTLHGHLKLDNISKIAFVSLPFRGKESYNIAFIANNGQTIFKVYLGRDAERQLFPEQVQKFKAFI
>CP031554.1|AXO04816.1|243991_244255_+|hypothetical-protein
MDREYLSDLALSLTLKINNDTNQALDVTFISAYVNDSPVDFLPLTFKQGESIEVKLSNASSDMLWQYEASPSVSVMTKGFELDDILK
>CP031554.1|AXO02867.1|250145_250991_+|hypothetical-protein
MAFDFKNMICFGVAGNFAGHLEQAGEAADFISVQTEEEIQPKAIFPFYVPSETLNPEHQFLATFPLTHDQICFPKQKGADNLQIEPEIALICDIEYQEKQVISLTPRFFTAYNDCSIRRPDAKKISEKKNWGEKTKGLANTLLPLSSFAPGCELDHYHIACFHKRGTDFNEYGIDSPALGYSYFHQKLLNWIITKMNTQPDQGPMNDIPALLAKANYPKQAVIGIGATRYTAFGERNFLQIGDTSIVVVYNAKKYDHETIVSMAKQNRFAEDIAALVQVVV
>CP031554.1|AXO02868.1|251053_251992_-|bifunctional-biotin-operon-repressor/biotin--[acetyl-CoA-carboxylase]-ligase
MQNVLALLASYQQLSLAELTALLGYSEQDILHNIEKLKQQGIQIEQQVQHFRLIPQLSRLNESYLTQALAPYPLYIKPIINSTNQFLLDNIAHLEKGAICLAEYQTAGRGRRGRQWLSPFAGQVIMSLYWACDQKVNLEGLSLVVGMAIAETLKQAGALNIGLKWPNDVLLHGRKLAGILVEIANRQNNQHNLVIGFGINLSFPKQTQQIDQPWAELIEVLPTIDRNKLIAELGKKLIARLQHFEQAGIDEAFRQDWRDMDAYFGEEVHVLTENHKITGIAQGIDKRGYLQLITSEGMQYFNGGEVSLRKAS

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Crispr_ID: CP031554_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031554_3

765524-766871

Unclear

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTATACGGCAGTTAAC	CRISPRCasFinder
TTTCTAAGCTGCCTATACGGCAGTTAAC	CRT
TTTCTAAGCTGCCTATACGGCAGTTAAC	PILER-CR

22 spacers

cas3

The CRISPR arrays of CP031554_3

>merge|CP031554|3|765524-766871|CRISPRCasFinder,CRT,PILER-CR
AATTGAAACTGCCTATACGGCAGTTAACACCAATCTGATAATCGAGCCAAGATCGCTTTATTTCTAAGCTGCCTACACGGCAGTTAACAAGAGCAGAAAACAGAAGAATTGGAAGATGACTTTCTAAGCTACCTACACGGCAGTTAACAGTGTAATTCCGCTCCGTTGCTTAAAATAATCTTTCTAAGCTGCCTACACGGCAGTTAACGTATGAGTTCGGCATTTGCAGAGCTTAAAGCTTTTCTAAGCTGCCTACACGGCAGTTAACTTGATCCTTTTACGCGTAAACAGAATGCTTTTTTTCTAAGCTGCCTATACGGCAGTTAACTATTCAGAATCAAAACGAATACCCAAAATTGCTTTCTAAGCTGCCTATACGGCAGTTAACCGGGTGCGCAAATGGTTTGCGACAAAAGGCGATTTCTAAGCTGCCTATACGGCAGTTAACAACTATAATAAAAAAGGCTGTTGCCATTGCTATTTCTAAGCTGCCTATACGGCAGTTAACATGACTTTTGGGGAGCTATCGGCATAGTGCTTTTTCTAAGCTGCCTATACGGCAGTTAACAAGAGCCACGATTCACTTGTAACGCTTGGATCTTTCTAAGCTGCCTATACGGCAGTTAACACGTGATGACGTGCTCATCTGCGCTGTGGCTTTTTCTAAGCTGCCTATACGGCAGTTAACGCTTACGGGGATTAACGTGAGCGCGGACACTTTTTCTAAGCTGCCTATACGGCAGTTAACCGTTTCTTCATTTCGCTTACGCTCCCGTTGATTTTCTAAGCTGCCTATACGGCAGTTAACTTTGATCCATCAAGAAGTGATCATGTGTTCATTTTCTAAGCTGCCTATACGGCAGTTAACGAATACGCGGGGACAGCTTACAACCTTGCAACTTTCTAAGCTGCCTATACGGCAGTTAACAAAGGCAATATGCGACAAATTCCAGAGATTTTTTTCTAAGCTGCCTATACGGCAGTTAACGCTCGCGGAAATCTACCCCGATTTAGACACATTTTCTAAGCTGCCTATACGGCAGTTAACCTCGGGATAATCATCCACTGCTCACCTGAAATTTTCTAAGCTGCCTATACGGCAGTTAACTACGCCATTATGGCGACTGACTTCCGCGATAATTTCTAAGCTGCCTATACGGCAGTTAACACTTGTGCAAGGGTTGTGTGTTCATAGGCTTTTTTCTAAGCTGCCTATACGGCAGTTAACTAAAATTAAAACTATCGTCGCTTGCTTGTAGCTTTCTAAGCTGCCTATACGGCAGTTAACACTAGCGGAGGCTCAACAATGACGGAAGGTAATTTCTAAGCTGCCTATACGGCAGTTAAC

>CP031554|3|3|765524-766871|CRISPRCasFinder
AATTGAAACTGCCTATACGGCAGTTAAC	ACCAATCTGATAATCGAGCCAAGATCGCTTTA
TTTCTAAGCTGCCTACACGGCAGTTAAC	AAGAGCAGAAAACAGAAGAATTGGAAGATGAC
TTTCTAAGCTACCTACACGGCAGTTAAC	AGTGTAATTCCGCTCCGTTGCTTAAAATAATC
TTTCTAAGCTGCCTACACGGCAGTTAAC	GTATGAGTTCGGCATTTGCAGAGCTTAAAGCT
TTTCTAAGCTGCCTACACGGCAGTTAAC	TTGATCCTTTTACGCGTAAACAGAATGCTTTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TATTCAGAATCAAAACGAATACCCAAAATTGC
TTTCTAAGCTGCCTATACGGCAGTTAAC	CGGGTGCGCAAATGGTTTGCGACAAAAGGCGA
TTTCTAAGCTGCCTATACGGCAGTTAAC	AACTATAATAAAAAAGGCTGTTGCCATTGCTA
TTTCTAAGCTGCCTATACGGCAGTTAAC	ATGACTTTTGGGGAGCTATCGGCATAGTGCTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	AAGAGCCACGATTCACTTGTAACGCTTGGATC
TTTCTAAGCTGCCTATACGGCAGTTAAC	ACGTGATGACGTGCTCATCTGCGCTGTGGCTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	GCTTACGGGGATTAACGTGAGCGCGGACACTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	CGTTTCTTCATTTCGCTTACGCTCCCGTTGAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TTTGATCCATCAAGAAGTGATCATGTGTTCAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	GAATACGCGGGGACAGCTTACAACCTTGCAAC
TTTCTAAGCTGCCTATACGGCAGTTAAC	AAAGGCAATATGCGACAAATTCCAGAGATTTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	GCTCGCGGAAATCTACCCCGATTTAGACACAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	CTCGGGATAATCATCCACTGCTCACCTGAAAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TACGCCATTATGGCGACTGACTTCCGCGATAA
TTTCTAAGCTGCCTATACGGCAGTTAAC	ACTTGTGCAAGGGTTGTGTGTTCATAGGCTTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TAAAATTAAAACTATCGTCGCTTGCTTGTAGC
TTTCTAAGCTGCCTATACGGCAGTTAAC	ACTAGCGGAGGCTCAACAATGACGGAAGGTAA
TTTCTAAGCTGCCTATACGGCAGTTAAC

>CP031554|3|2|765524-766871|CRT
AATTGAAACTGCCTATACGGCAGTTAAC	ACCAATCTGATAATCGAGCCAAGATCGCTTTA
TTTCTAAGCTGCCTACACGGCAGTTAAC	AAGAGCAGAAAACAGAAGAATTGGAAGATGAC
TTTCTAAGCTACCTACACGGCAGTTAAC	AGTGTAATTCCGCTCCGTTGCTTAAAATAATC
TTTCTAAGCTGCCTACACGGCAGTTAAC	GTATGAGTTCGGCATTTGCAGAGCTTAAAGCT
TTTCTAAGCTGCCTACACGGCAGTTAAC	TTGATCCTTTTACGCGTAAACAGAATGCTTTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TATTCAGAATCAAAACGAATACCCAAAATTGC
TTTCTAAGCTGCCTATACGGCAGTTAAC	CGGGTGCGCAAATGGTTTGCGACAAAAGGCGA
TTTCTAAGCTGCCTATACGGCAGTTAAC	AACTATAATAAAAAAGGCTGTTGCCATTGCTA
TTTCTAAGCTGCCTATACGGCAGTTAAC	ATGACTTTTGGGGAGCTATCGGCATAGTGCTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	AAGAGCCACGATTCACTTGTAACGCTTGGATC
TTTCTAAGCTGCCTATACGGCAGTTAAC	ACGTGATGACGTGCTCATCTGCGCTGTGGCTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	GCTTACGGGGATTAACGTGAGCGCGGACACTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	CGTTTCTTCATTTCGCTTACGCTCCCGTTGAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TTTGATCCATCAAGAAGTGATCATGTGTTCAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	GAATACGCGGGGACAGCTTACAACCTTGCAAC
TTTCTAAGCTGCCTATACGGCAGTTAAC	AAAGGCAATATGCGACAAATTCCAGAGATTTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	GCTCGCGGAAATCTACCCCGATTTAGACACAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	CTCGGGATAATCATCCACTGCTCACCTGAAAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TACGCCATTATGGCGACTGACTTCCGCGATAA
TTTCTAAGCTGCCTATACGGCAGTTAAC	ACTTGTGCAAGGGTTGTGTGTTCATAGGCTTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TAAAATTAAAACTATCGTCGCTTGCTTGTAGC
TTTCTAAGCTGCCTATACGGCAGTTAAC	ACTAGCGGAGGCTCAACAATGACGGAAGGTAA
TTTCTAAGCTGCCTATACGGCAGTTAAC

>CP031554|3|2|765584-766871|PILER-CR
TTTCTAAGCTGCCTACACGGCAGTTAAC	AAGAGCAGAAAACAGAAGAATTGGAAGATGAC
TTTCTAAGCTACCTACACGGCAGTTAAC	AGTGTAATTCCGCTCCGTTGCTTAAAATAATC
TTTCTAAGCTGCCTACACGGCAGTTAAC	GTATGAGTTCGGCATTTGCAGAGCTTAAAGCT
TTTCTAAGCTGCCTACACGGCAGTTAAC	TTGATCCTTTTACGCGTAAACAGAATGCTTTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TATTCAGAATCAAAACGAATACCCAAAATTGC
TTTCTAAGCTGCCTATACGGCAGTTAAC	CGGGTGCGCAAATGGTTTGCGACAAAAGGCGA
TTTCTAAGCTGCCTATACGGCAGTTAAC	AACTATAATAAAAAAGGCTGTTGCCATTGCTA
TTTCTAAGCTGCCTATACGGCAGTTAAC	ATGACTTTTGGGGAGCTATCGGCATAGTGCTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	AAGAGCCACGATTCACTTGTAACGCTTGGATC
TTTCTAAGCTGCCTATACGGCAGTTAAC	ACGTGATGACGTGCTCATCTGCGCTGTGGCTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	GCTTACGGGGATTAACGTGAGCGCGGACACTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	CGTTTCTTCATTTCGCTTACGCTCCCGTTGAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TTTGATCCATCAAGAAGTGATCATGTGTTCAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	GAATACGCGGGGACAGCTTACAACCTTGCAAC
TTTCTAAGCTGCCTATACGGCAGTTAAC	AAAGGCAATATGCGACAAATTCCAGAGATTTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	GCTCGCGGAAATCTACCCCGATTTAGACACAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	CTCGGGATAATCATCCACTGCTCACCTGAAAT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TACGCCATTATGGCGACTGACTTCCGCGATAA
TTTCTAAGCTGCCTATACGGCAGTTAAC	ACTTGTGCAAGGGTTGTGTGTTCATAGGCTTT
TTTCTAAGCTGCCTATACGGCAGTTAAC	TAAAATTAAAACTATCGTCGCTTGCTTGTAGC
TTTCTAAGCTGCCTATACGGCAGTTAAC	ACTAGCGGAGGCTCAACAATGACGGAAGGTAA
TTTCTAAGCTGCCTATACGGCAGTTAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP031554.1\|AXO03305.1\|753630_755217_-\|L-lactate-permease	unknown	unknown	gnl\|CDD\|224535
CP031554.1\|AXO04829.1\|770199_773103_+\|RNA-polymerase-associated-protein-RapA	unknown	unknown	gnl\|CDD\|235319
CP031554.1\|AXO03316.1\|769219_769924_-\|nicotinamide-riboside-transporter-PnuC	unknown	unknown	gnl\|CDD\|225742
CP031554.1\|AXO03306.1\|755575_756943_-\|adenylosuccinate-lyase	unknown	unknown	gnl\|CDD\|236452
CP031554.1\|AXO03308.1\|758731_760174_+\|glycoside-hydrolase-family-32-protein	unknown	unknown	gnl\|CDD\|224536
CP031554.1\|AXO03322.1\|777105_777441_-\|XRE-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
CP031554.1\|AXO03313.1\|764506_765472_+\|lipopolysaccharide-heptosyltransferase-RfaC	unknown	unknown	gnl\|CDD\|236809
CP031554.1\|AXO03317.1\|773183_773843_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	unknown	unknown	gnl\|CDD\|236659
CP031554.1\|AXO03320.1\|774933_776301_+\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236430
CP031554.1\|AXO03310.1\|761447_762872_+\|PTS-maltose-transporter-subunit-IIBC	unknown	unknown	gnl\|CDD\|131051
CP031554.1\|AXO03309.1\|760199_761219_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|131470
CP031554.1\|AXO03318.1\|773906_774476_+\|Der-GTPase-activating-protein-YihI	unknown	unknown	gnl\|CDD\|367878
CP031554.1\|AXO04828.1\|757767_758694_+\|aminoimidazole-riboside-kinase	unknown	unknown	gnl\|CDD\|236514
CP031554.1\|AXO03314.1\|767018_768347_-\|ATP-dependent-RNA-helicase-SrmB	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|236877
CP031554.1\|AXO03319.1\|774481_774910_+\|DUF2489-domain-containing-protein	unknown	unknown	gnl\|CDD\|378470
CP031554.1\|AXO03311.1\|762987_763395_+\|copper-chaperone-PCu(A)C	unknown	unknown	gnl\|CDD\|225403
CP031554.1\|AXO03315.1\|768458_769172_+\|tRNA-(adenosine(37)-N6)-methyltransferase-TrmM	unknown	unknown	gnl\|CDD\|226608
CP031554.1\|AXO03307.1\|756970_757582_-\|lysogenization-regulator-HflD	unknown	unknown	gnl\|CDD\|225467
CP031554.1\|AXO03321.1\|776341_777010_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380324
CP031554.1\|AXO03312.1\|763463_764510_+\|lipopolysaccharide-heptosyltransferase-II	unknown	unknown	gnl\|CDD\|182835

Protein	Function_ID	Function_description	E-value
CP031554.1\|AXO03305.1\|753630_755217_-\|L-lactate-permease	gnl\|CDD\|224535	COG1620, LldP, L-lactate permease [Energy production and conversion].	6.14413e-167
CP031554.1\|AXO04829.1\|770199_773103_+\|RNA-polymerase-associated-protein-RapA	gnl\|CDD\|235319	PRK04914, PRK04914, RNA polymerase-associated protein RapA.	0
CP031554.1\|AXO03316.1\|769219_769924_-\|nicotinamide-riboside-transporter-PnuC	gnl\|CDD\|225742	COG3201, PnuC, Nicotinamide mononucleotide transporter [Coenzyme metabolism].	5.27246e-73
CP031554.1\|AXO03306.1\|755575_756943_-\|adenylosuccinate-lyase	gnl\|CDD\|236452	PRK09285, PRK09285, adenylosuccinate lyase; Provisional.	0
CP031554.1\|AXO03308.1\|758731_760174_+\|glycoside-hydrolase-family-32-protein	gnl\|CDD\|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	2.82868e-175
CP031554.1\|AXO03322.1\|777105_777441_-\|XRE-family-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.65249e-05
CP031554.1\|AXO03313.1\|764506_765472_+\|lipopolysaccharide-heptosyltransferase-RfaC	gnl\|CDD\|236809	PRK10964, PRK10964, lipopolysaccharide heptosyltransferase RfaC.	0
CP031554.1\|AXO03317.1\|773183_773843_+\|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA	gnl\|CDD\|236659	PRK10158, PRK10158, bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA.	6.19774e-102
CP031554.1\|AXO03320.1\|774933_776301_+\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236430	PRK09249, PRK09249, coproporphyrinogen dehydrogenase.	0
CP031554.1\|AXO03310.1\|761447_762872_+\|PTS-maltose-transporter-subunit-IIBC	gnl\|CDD\|131051	TIGR01996, Includes:_Phosphotransferase_enzyme_IIB_component, PTS system, sucrose-specific IIBC component. This model represents the fused enzyme II B and C components of the sucrose-specific PTS sugar transporter system. Sucrose is converted to sucrose-6-phosphate in the process of translocation into the cell. Some of these transporters lack their own IIA domains and instead use the glucose IIA protein (IIAglc or Crr). The exceptions to this rule are Staphylococci, Streptococci, Lactococci, Lactobacilli, etc. which contain their own A domain as a C-terminal fusion. This family is closely related to the trehalose transporting PTS IIBC enzymes and the B and C domains of each are described by subfamily-domain level TIGRFAMs models (TIGR00826 and TIGR00852, respectively).	0
CP031554.1\|AXO03309.1\|760199_761219_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|131470	TIGR02417, Fructose_repressor_Catabolite_repressor/activator., D-fructose-responsive transcription factor. Members of this family belong the lacI helix-turn-helix family (pfam00356) of DNA-binding transcriptional regulators. All members are from the proteobacteria. Characterized members act as positive and negative transcriptional regulators of fructose and sucrose transport and metabolism. Sucrose is a disaccharide composed of fructose and glucose; D-fructose-1-phosphate rather than an intact sucrose moiety has been shown to act as the inducer. [Regulatory functions, DNA interactions].	0
CP031554.1\|AXO03318.1\|773906_774476_+\|Der-GTPase-activating-protein-YihI	gnl\|CDD\|367878	pfam04220, YihI, Der GTPase activator (YihI). YihI activates the GTPase activity of Der, a 50S ribosomal subunit stability factor. The stimulation is specific to Der as YihI does not stimulate the GTPase activity of Era or ObgE. The interaction of YihI with Der requires only the C-terminal 78 amino acids of YihI. A yihI deletion mutant is viable and shows a shorter lag period, but the same post-lag growth rate as a wild-type strain. yihI is expressed during the lag period. Overexpression of yihI inhibits cell growth and biogenesis of the 50S ribosomal subunit. YihI is an unusual, highly hydrophilic protein with an uneven distribution of charged residues, resulting in an N-terminal region with high pI and a C-terminal region with low pI.	8.55528e-59
CP031554.1\|AXO04828.1\|757767_758694_+\|aminoimidazole-riboside-kinase	gnl\|CDD\|236514	PRK09434, PRK09434, aminoimidazole riboside kinase; Provisional.	0
CP031554.1\|AXO03314.1\|767018_768347_-\|ATP-dependent-RNA-helicase-SrmB	gnl\|CDD\|236877	PRK11192, PRK11192, ATP-dependent RNA helicase SrmB; Provisional.	0
CP031554.1\|AXO03319.1\|774481_774910_+\|DUF2489-domain-containing-protein	gnl\|CDD\|378470	pfam10675, DUF2489, Protein of unknown function (DUF2489). This is a bacterial family of uncharacterized proteins.	1.12596e-47
CP031554.1\|AXO03311.1\|762987_763395_+\|copper-chaperone-PCu(A)C	gnl\|CDD\|225403	COG2847, COG2847, Copper(I)-binding protein [Inorganic ion transport and metabolism].	1.12449e-42
CP031554.1\|AXO03315.1\|768458_769172_+\|tRNA-(adenosine(37)-N6)-methyltransferase-TrmM	gnl\|CDD\|226608	COG4123, COG4123, Predicted O-methyltransferase [General function prediction only].	2.77606e-93
CP031554.1\|AXO03307.1\|756970_757582_-\|lysogenization-regulator-HflD	gnl\|CDD\|225467	COG2915, COG2915, Uncharacterized protein involved in purine metabolism [General function prediction only].	9.09394e-109
CP031554.1\|AXO03321.1\|776341_777010_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|380324	cd02149, NfsB-like, nitroreductase similar to Escherichia coli NfsB. NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family includes FRase I in Vibrio fischeri, wihich reduces FMN into FMNH2 as part of the bioluminescent reaction. The family also includes oxygen-insensitive nitroreductases that use NADH or NADPH as an electron donor in the ping pong bi bi mechanism. This type of nitroreductase can be used in cancer chemotherapy to activate a range of prodrugs.	3.45531e-76
CP031554.1\|AXO03312.1\|763463_764510_+\|lipopolysaccharide-heptosyltransferase-II	gnl\|CDD\|182835	PRK10916, PRK10916, ADP-heptose--LPS heptosyltransferase RfaF.	0

>CP031554.1|AXO03313.1|764506_765472_+|lipopolysaccharide-heptosyltransferase-RfaC
MKICLIKTSSMGDILHSLPALTDAQRALPNLQVDWVVEESFAEIPHWHSAVRQVIPIALRRWRKTPFTALTRKQWKTYRTLLQSEQYDAVIDAQGLLKSALFATRLARGTRHGYDRHSIREPIAACFYDKKYAISYQQHAVERIRQLFAQSLNYPLPHTQGDYGIARHFPQHAQTMPYVLFFHGTTRQDKFLPDKQWRTLAEKLTAQGIQIHVPWSNPQEKQRAERIAQGLDLVTILPKSTLSELAQQIVNASAVVSVDTGLAHLSAALDKTNLTLYGATDPKLIGSYGKNQHYLVAESMDKIEADEIFQKLTALLSLNTI
>CP031554.1|AXO03312.1|763463_764510_+|lipopolysaccharide-heptosyltransferase-II
MHILIIGPSWVGDMMMSHSLYQTLKQQYPQCEIDVMAPNWCKPLLERMPEVRQAITMPLGHGAFALGDRYRLGKALRHQYDMAIVLPNSLKSAFIPFFAKIPLRRGWKGESRYLFLNDLRSNKKDYPMMVQRYIALAFEKGAVPKAEDLPRPVPYLTVDPITQQHTLKKFEKQTALISPRPSIGFCPGAEFGPAKRWPHYHYAKLAEMLIQQGYAIRLFGSAKDEAVGEEIRQALPETMRHFCINLAGQTSLNEAVDLIADCTAIVTNDSGLMHIAAAVQRPLVALYGPTSPTYTPPLSEKAVIIRLIEDGLIKVRKGKDSDEGYHQSLIDIQPELVFDKLTGLLANT
>CP031554.1|AXO03311.1|762987_763395_+|copper-chaperone-PCu(A)C
MKSLTQLLFILTALLPTSLFAHIHVEQAQMFSAKAGEPSAIFMNIHNTGNEDVSLALVQSDIRADIVLHGTQHGKMIEVTGINLPAHQMTALKRGGLHIMVFNVEQDLNAGDSFPLRLLFDNGEIMHIEAKIIQY
>CP031554.1|AXO03310.1|761447_762872_+|PTS-maltose-transporter-subunit-IIBC
MNFSQIAQQVIDKLGGKDNISAAAHCATRLRIVVKNENLIDKKGIENIEGVKGQFAVAGQYQIIFGSGTVNKVYAELSKLLGIGDMTTSEVAAAGTEKQGLLQRLVKGLADIFVPIIPAIVAGGLLMGIHSMLTAKGFFVEEKNVVDLYPAIADLVDFINTIANAPFVFLPVLLGFSATRKFGGNPFLGAALGMLLVHPALSDGWNYALTLTKGNIQYWHIFGLEIERVGYQGTVIPVLVASWVLATLEKNLRKVVPSFLDNLITPLFALFITGLLAFTVIGPIGREAGSLISTGLTWLYDTLGFVGGAIFGTLYAPIVITGMHQTFIAVETQLLAEVARTGGTFIFPIAAMSNIAQGAACLGAAYVMKDAKVRGIGVPSGISALLGITEPAMFGVNLRYRYPFISAMIGAGISSAVIALFNVKAIALGAAGLPGIPSIKPDSLAMYCVGMLISASIAFTLTVILGKRAQLKAE
>CP031554.1|AXO03309.1|760199_761219_+|LacI-family-DNA-binding-transcriptional-regulator
MSITNKKRITLSDIAKCCGLSTTTVSMILNNRGEEFKIKAETCQRVKAIAEQQGYRANVYAKSLKMQRSNVIGFVIPDLTNYGFACTAKILEKQCRENGLQLIIACSDDNPQQEKLAIERLLDRQIDFLITAPTHQDPSYYQKIGQHTPILQLDRYVPDLALNYVISNDSEHITALICRLCDQYQLTEFMYFGGQRTLSPSESRLAGFLQGLKQANLNLKKEWILHRTYQPESGYQMLAETEAKLGRLPQAIFTASYTLLEGVLRYLTEQKKMDLLLNRQLHLATFDDHDILNALPFHIHSIKQNHPQLAQQIFQHIMRYFAGKKSPNQKIDCDVIYRD
>CP031554.1|AXO03308.1|758731_760174_+|glycoside-hydrolase-family-32-protein
MYIFNQGKYKSLHAQEVGELAQIRQHVLRDTQFRPTYHLAPETGLLNDPNGLVFDGEKYHIFYQWFPYAAIHGMKHWKHFITYDFHHFQAADPLIPDELFESHGCYSGGALLWQDQIVAFYTGNTRNAENQRIPHQNIAIFKKDGTLLKKRCLLNQAPTGYTEHVRDPKPFITEEGKIRFILGAQREDLSGTALIYEMTDLDATPQLIGEFKLPDFDNQQVFMWECPDLLKLQEQDLFLWSPQGKAQKTYCFQNHYHATYALGQYANLHFSAQHIEELDYGFDFYAPQSIQGSEGIYYAWVGLPDLTYPTDEYQWHSMLSLPRQFSIQQGILYQRPIPQVYAQCLPAHKYWVEGKQQIPHLDRSYVAFDAENQPFTLRFFTNQRGQQLILRYQNGILTLDRTYTTQTALMQQFGEQRHCILPQLNHVEIFFDRSVVEIFLNQGEKVMTSRFFIADRENALDSSRPLCVSVAELKPIILTP
>CP031554.1|AXO04828.1|757767_758694_+|aminoimidazole-riboside-kinase
MGKIWVLGDAVVDLIPEGENTYLRCAGGAPANVAVGIARLGATTGFIGRVGDDPLGRFMLNKLQQENVCTQYMHLDPKQLTSTVIVDLKEGERSFTFMVNPSADQFLELSDLPHFNPNDWLHCCSIALINEPSRSSTFAAIHRIKAEGGFFSFDPNLRESLWNSPAEMKTVVNQVVALADVLKFSEEELLFLTDSDTLSDATAKLTQHYPDKLIIVTLGKLGATYYLQGKSQLISSKKALIPVDTTGAGDAFVSGLLFGISQVKNWQNPTALVEIIKQANACGALATTAKGAMSALPNKQQLDAFLAE
>CP031554.1|AXO03307.1|756970_757582_-|lysogenization-regulator-HflD
MANYYDITLALAGVCQAAKLVQQFAHEGQADQAAFETSLNTLLQIYPEDTLAVFGGKAQNLKLGLETLLEQMHGTGSDLSRYWISLLALESKLNKDPHAKAELARRIQYLPTQLEHDDLLDEQMLSTLASIYVDVISPLGKKIQVTGSTLYLQQLAMHHRIRACLLAGIRSAVLWRQVGGTKWQVLFSRRKIIAMAKQIYSSL
>CP031554.1|AXO03306.1|755575_756943_-|adenylosuccinate-lyase
MQLNALTALSPIDGRYQDKVSSLRSIFSEFGLLKFRVTVEVRWLQKLAATDQIQEVSLLSQEANDYLNHIVENFSVQDAERIKEIERTTNHDVKAVEYFLKEKSEALPELAKISEFIHFACTSEDINNLSHALMLKTAREEVILPEWQNLIADISALANEYKTIPLLSRTHGQPASPSTIGKEMANVVYRLQRQFKQLQQIDILGKINGAVGNYNAHLSAYPDIDWHQFSEEFVTSLGLTWNPYTTQIEPHDYIAEFFDNVARFNTIIIDFDRDLWGYIALNHFKQRTIAGEIGSSTMPHKVNPIDFENSEGNLGLANAVMAHLGAKLPVSRWQRDLTDSTVLRNLGVGLGYCLIAYAATRKGISKLEVNEQHLRDELDQNWEVLAEPIQTVMRRYGIEKPYEKLKALTRGKRVDAEAMREFIETLDIPAQEKIRLQQMTPATYIGAAVELVEKL
>CP031554.1|AXO03305.1|753630_755217_-|L-lactate-permease
MVFFLSILPIVLLIYLMVKRNSLPSYIALPLIAVLTYLLQAFYFGTDLTRLNANVIAGLIATQTPITIIFGAILFNRMMEVSGSTDVLRKWLANINPNPVAQIMIIGWAFAFMIEGASGFGTPAAIAAPILMGLGFKPLQVAMLALVMNSVPVSFGAVGTPTWFGFGPLGLSEDVVLEVGQKTAFIHFIAAFVIPVLALRFLVSWQQIKQNLVFIYISILACTIPYFLLAQVNYEFPALVGGAIGLFISILVANKGIGVSKTAQAEIQLEKVEFGVLVKALFPTMMLIAILIVTRIHQLGIKQLLNDATTWFSVSLGAFGEFKVSQALILSLNNILGQGINESYKTLYVPSLIPFIVTVIISIFVFKLNGTKAKTIAVSTYQQTKKPFFALLGALVMVKLMLVGNENYDSMVITIGKTFADVTGDKWVYFSSYLGAIGAFFSGSNTVSNLTFGGIQLSIAETTGMSVPLILALQSVGGAMGNMVCLNNIIAVCTVLNVSNQEGSILKRTVVPMFLYGVIAALVAVVIY
>CP031554.1|AXO03314.1|767018_768347_-|ATP-dependent-RNA-helicase-SrmB
MTLATFQDFDLAPALLKALAKKGYTRPTAIQQETIPAAMEQRDVLGSAPTGTGKTAAFLLPAIQHLLDYPRRKPGAPRILILTPTRELAMQVAEQAESFAEFTNLSIATITGGVAYQNHGEIFNSNQDIVVATPGRLLQYIKEENFDCRSVEILIFDEADRMLQMGFGQDAEKIAAETRWRKQTLLFSATLEGELLVDFASRLLTDPVQIDAEPSRRERKKIQQWYYHADSNEHKIKLLARFIDEEQVSRGIVFVRRREDVRELSETLRKRGIRSTYLEGEMAQTQRNNAIDKLKNGIVTVLVATDVAARGIDIEDVSHVMNFDLPYSADTYLHRIGRTARAGKKGVAVSFVEAHDYKLLGKIKRYTQELLKARIIEGLAPRTKAPKEGEVKTVSKKQKARIKAKREEKQKQEQKKKVKLRHKDTKNIGKRRKSNTPPANAE
>CP031554.1|AXO03315.1|768458_769172_+|tRNA-(adenosine(37)-N6)-methyltransferase-TrmM
MSAKQNGFTFKQFHIEHHRCAMKVGTDGILLGAWADVSQAERILDLGTGTGLIALMLAQRSTKESEIHAVELDQAAYLQAQANIHASPWAQRVHVYQQDAAEFCRNAVNKFDLIVANPPYFPQGVDCATPQRDLARYTATHRHVDWLNWASHCLSEQGKISMVLPFEAGETLLKQTALYCIARCEVITKKGKAPQRLLLTFSLQAQPLQPSQLIIYDESNRYHPDFIGLTKDFYLAF
>CP031554.1|AXO03316.1|769219_769924_-|nicotinamide-riboside-transporter-PnuC
MNLQAVKNEFLGGWKPFEVAWLSLFLIAQIVIYIQNPDSILGMISGISGILCVVFVSKGKVSNYFFGLIFAYTYFYVAWQANYLGEMNTVLYVYIPAQFIGYFLWRENLQKGSEGAESVIAKSLTLKGWAIVLGTITIGTLLFVQALNAAGGSSTGLDGLTTVIVVVAQLLMILRYREQWLLWIALNVISIVLWTQAKEGSLAMVTMYSAYLLNSLYGYYNWTKLEKAHRQSVQ
>CP031554.1|AXO04829.1|770199_773103_+|RNA-polymerase-associated-protein-RapA
MTFAVGQRWMSESENNLGLGLIVAIDMRTVTILFPASEEQRIYALNSAPLTRVLFQIGDEIVHHEGWKGNVLDILENNGVAFYLLKRQDNGEEITIQERDIAHQMTFSKPQDRLFTTQIDRNEHFTLRYQALTHQQAQFQSPLRGLRGIRAGLIPHQLHIAREVGQRTAPRVLLADEVGLGKTIEAGMILQQQLFAEKVERVLIIVPETLQHQWLVEMLRRFNLHFALFDEERCADFEDPASALWINPFSTESQIICALDWLCEKPKRVEQLLEAGFDMLIVDEAHHLGWSEHNPSLEYQLVEQLARQIPAVLLLTATPEQLGQESHFARLSLLDPDRFYDYQAFVQEQQQYQPVADAVQSLLADKPLSTVEKNHIADLLSEQDVEPMLKVIDSQAHDEQKALARQELIDNLIDRHGTSRVLFRNTRQGVKSFPHRTYNQITLELPKQYNNAANVLAMLGEKSENDSFYPEQMFQKLNPDARWWEFDPRLAWLITFLKNHREEKVLVICRHANTAIQLEQALREKEAIRAAVFHEKLSIVERDRAAAYFAQQEDGAQVLLSSSIGSEGRNFQFASHLVLFNLPDDPDLLEQCIGRLDRIGQSRDIQIHVPCFADTAQVVLARWYHEGLNAFEETCPMGMTLFETHQTQLNKFLQKPTALEGFAEFVSLTRKQQHELKQALEKGRDRLLELNSNGGEQAQQLATDIAEQDSTTELVNFTLNLFDIIGVDQEDLGEKSIVITPASNMLVPDFPGLKEEGATVTFDRQLSLAREDVEFMSWDHPLIRHGIDLITSGDIGKSAVSLLINKALPAGTLLLEMIYVVEAQAPKGLQLTRFLPPTPIRLLLDQKGNNLAEQVSFNALQKQLKPIGKNMANKVVKMVRPNIEQLVKLSEQKIVAQAQQIIHNTQQLADQTLSAELNRLTALQAVNKNIRQDEVDALENIRSQSLAQLQQATWRLDSLRVIVSNKE
>CP031554.1|AXO03317.1|773183_773843_+|bifunctional-tRNA-pseudouridine(32)-synthase/23S-rRNA-pseudouridine(746)-synthase-RluA
MALISYTPPTDPYLDIVHYDDHFVVINKPSGLLSVPGNQPQYYDSAMSRVKEKYGFCEPAHRLDMSTSGLILFALSKAADRELKRQFREREPKKHYQALVWGHLEEDQGEVNLPLICDWENRPRQKICFERGKPALTLYEVLARYPNNTTRVKLTPITGRSHQLRLHMLALGHPILGDKFYAPPQAKALSPRLCLHAEQLAFRHPITQEWLSFSAPPAF
>CP031554.1|AXO03318.1|773906_774476_+|Der-GTPase-activating-protein-YihI
MARKKKTRRVSDIMPARKVDKKVELPKGKPGKKLTRYELDAKAREDKKKKKRKGLASGSRHSATENNNKHQALEKKDPRIGSRKKVPLVVEFVNKPEKGMTIPPMKLEEKLPKQDPMLELELLESNECLNQLLDDLEAGKTLSAEDQQFVDDCLDRIAELMDELGISEDDDPEEDLLRTFEKIDINQFR
>CP031554.1|AXO03319.1|774481_774910_+|DUF2489-domain-containing-protein
MWTNILLILAVLVIVAMASYAGYLLLALQKQKKAIANMRTARSQRLTESIVIIAKAMQNGDCNHSEGVIRLKMLLDPLGKKLKNYQAMYQLYEVVMEMPTHEKRRELKKNERMRLDLQRESAEAELEQKIRLELQQLLIDMK
>CP031554.1|AXO03320.1|774933_776301_+|oxygen-independent-coproporphyrinogen-III-oxidase
MSDIVWDLALIQKYNQSGPRYTSYPTALEFNENYTNQDFIQATKRYPNRPLSLYVHIPFCHKLCYFCACNKTITRHQHKADIYLDFLEREIENRASLFKNRIATQVHWGGGTPTYLTEQQSARLMAMLRKHFTIAPDAEISIEMDPREIELNMLDHLRRIGFNRMSMGVQDFNKDVQKAINRVQDEDFIEALLKRARELGFQSTNLDLIYGLPLQNVDSFMFTLQKVIALNSDRLSVFNYAHLPSRFAGQAKIKNEQLPAPETKLTILQKMIETLGDAGYKFIGMDHFAKPDDELAIAQKQGVLHRNFQGYTTQEECDLLGLGVSAISLLGDTYAQNQKELKHYYTAIDNTGIALHKGFAMSEEDCLRRDVIKQLICNFKLDYQPIEQQYGIQFTSHFAEDLKLLAPLSEDGLLTIGEKDIQVSAKGRLLIRNICLCFDTYSREQAKRQQFSRII
>CP031554.1|AXO03321.1|776341_777010_+|NAD(P)H-dependent-oxidoreductase
MSISKTDILNAFHFRHACKAYDPSKKISEEDFRFILETGRLSPSSFGFEPWKFLVIENPDIKALIRDTAWGAKDKVMDCSHFVVVLVRQPETLLADGEYVQHMMRDIHHIPEEMRKIRQNFYRTFSEQDFALTENPKAFYDWACRQSYIALANMLTSAAMIGIDSTPIEGFPLEKMDHIFVEQGLYDPKTYKLSVMIAFGYRLNEPKAKTRQAFDDVVEWVR
>CP031554.1|AXO03322.1|777105_777441_-|XRE-family-transcriptional-regulator
MQITRRNASTKGASVAEIDRKKVRNEIIQAMLMGELSQGEALRKLRIEMFGINQQHYIQLVKVSRQTLSNIENDKGNYSVETINKVFKPFGLELGLVPVSKALLKELFSTA

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Crispr_ID: CP031554_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP031554_4

1100318-1100470

Orphan

Consensus_repeat	Method
TTATGACATTTATTTCTGGTTTTTA	CRISPRCasFinder

2 spacers

The CRISPR arrays of CP031554_4

>merge|CP031554|4|1100318-1100470|CRISPRCasFinder
ATTTGACACCTATTTCTTGTTTTCTAAATAATCTGACAGCTATTTCTAGTTTTTATGACATTTATTTCTGGTTTTTATGTCGTAAAAAATAGGATAAACCCTTATCCTTTCGTTGAATGAATAGCTAATTATGACATTTATTTCTAGTTTTTA

>CP031554|4|4|1100318-1100470|CRISPRCasFinder
ATTTGACACCTATTTCTTGTTTTCT	AAATAATCTGACAGCTATTTCTAGTTT
TTATGACATTTATTTCTGGTTTTTA	TGTCGTAAAAAATAGGATAAACCCTTATCCTTTCGTTGAATGAATAGCTAA
TTATGACATTTATTTCTAGTTTTTA

Protein	Signature genes	Signature genes Name	Protein_function
CP031554.1\|AXO03605.1\|1092376_1093948_+\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|380294
CP031554.1\|AXO03618.1\|1108078_1108543_-\|IS200/IS605-family-transposase	unknown	unknown	gnl\|CDD\|376616
CP031554.1\|AXO03610.1\|1097732_1099661_-\|transposase	unknown	unknown	gnl\|CDD\|366234
CP031554.1\|AXO03619.1\|1108728_1109787_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
CP031554.1\|AXO03602.1\|1086896_1088105_+\|IS4-like-element-ISVsa5-family-transposase	unknown	unknown	gnl\|CDD\|376573
CP031554.1\|AXO03603.1\|1088543_1089212_+\|putative-tetracyline-resistance-transcriptional-regulator-TetC	unknown	unknown	gnl\|CDD\|224228
CP031554.1\|AXO03609.1\|1096845_1097733_-\|transposase	unknown	unknown	gnl\|CDD\|377533
CP031554.1\|AXO03608.1\|1095769_1096888_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377670
CP031554.1\|AXO03611.1\|1099650_1100313_-\|heteromeric-transposase-endonuclease-subunit-TnsA	unknown	unknown	gnl\|CDD\|378037
CP031554.1\|AXO03613.1\|1101648_1104210_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273807
CP031554.1\|AXO03617.1\|1107274_1107958_+\|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|172608
CP031554.1\|AXO03615.1\|1105023_1105866_-\|divergent-polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|225416
CP031554.1\|AXO03607.1\|1094351_1095809_-\|hypothetical-protein	unknown	unknown	unknown
CP031554.1\|AXO03604.1\|1091705_1092323_+\|hypothetical-protein	unknown	unknown	unknown
CP031554.1\|AXO03622.1\|1112608_1113598_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|270265
CP031554.1\|AXO03606.1\|1094009_1094234_-\|tRNA-delta(2)-isopentenylpyrophosphate-transferase	unknown	unknown	unknown
CP031554.1\|AXO03620.1\|1109808_1111503_-\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224099
CP031554.1\|AXO03616.1\|1105862_1107134_-\|murein-hydrolase-activator-EnvC	unknown	unknown	gnl\|CDD\|227278
CP031554.1\|AXO03621.1\|1111505_1112594_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
CP031554.1\|AXO03614.1\|1104316_1105003_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP031554.1\|AXO03618.1\|1108078_1108543_-\|IS200/IS605-family-transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	5.24801e-42
CP031554.1\|AXO03610.1\|1097732_1099661_-\|transposase	gnl\|CDD\|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	1.85711e-13
CP031554.1\|AXO03619.1\|1108728_1109787_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.18237e-131
CP031554.1\|AXO03602.1\|1086896_1088105_+\|IS4-like-element-ISVsa5-family-transposase	gnl\|CDD\|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	7.26216e-11
CP031554.1\|AXO03603.1\|1088543_1089212_+\|putative-tetracyline-resistance-transcriptional-regulator-TetC	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.43536e-14
CP031554.1\|AXO03609.1\|1096845_1097733_-\|transposase	gnl\|CDD\|377533	pfam05621, TniB, Bacterial TniB protein. This family consists of several bacterial TniB NTP-binding proteins. TniB is a probable ATP-binding protein which is involved in Tn5053 mercury resistance transposition.	2.17903e-97
CP031554.1\|AXO03605.1\|1092376_1093948_+\|restriction-endonuclease	gnl\|CDD\|380294	NF033452, BREX_1_MTaseX, BREX-1 system adenine-specific DNA-methyltransferase PglX. This protein, PglX, is a site-specific DNA methyltransferase associated BREX (bacteriophage exclusion) type 1 systems. The phage resistance appears not to be through restriction-modification, as phage DNA appears not to get degraded, but it does manage to inhibit phage replication.	7.03455e-36
CP031554.1\|AXO03611.1\|1099650_1100313_-\|heteromeric-transposase-endonuclease-subunit-TnsA	gnl\|CDD\|378037	pfam08722, Tn7_Tnp_TnsA_N, TnsA endonuclease N terminal. The Tn7 transposase is composed of proteins TnsA and TnsB. DNA breakage at the 5' end of the transposon is carried out by TnsA, and breakage and joining at the 3' end is carried out by TnsB. The N terminal domain of TnsA is catalytic.	7.90649e-18
CP031554.1\|AXO03613.1\|1101648_1104210_+\|hypothetical-protein	gnl\|CDD\|273807	TIGR01785, Heme/hemopexin_utilization_protein_C, TonB-dependent heme/hemoglobin receptor family protein. This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	5.38741e-23
CP031554.1\|AXO03617.1\|1107274_1107958_+\|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|172608	PRK14118, gpmA, 2,3-diphosphoglycerate-dependent phosphoglycerate mutase.	2.91767e-174
CP031554.1\|AXO03615.1\|1105023_1105866_-\|divergent-polysaccharide-deacetylase-family-protein	gnl\|CDD\|225416	COG2861, COG2861, Uncharacterized protein conserved in bacteria [Function unknown].	2.8717e-116
CP031554.1\|AXO03622.1\|1112608_1113598_-\|extracellular-solute-binding-protein	gnl\|CDD\|270265	cd13547, PBP2_Fbp_like_2, Substrate binding domain of an uncharacterized ferric iron transporter, a member of the type 2 periplasmic binding fold superfamily. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. This periplasmic domain (Fbp) has high affinity for ferric iron and serves as the primary receptor for transport. After binding iron with high affinity, Fbp interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The ferric iron-binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	5.23366e-114
CP031554.1\|AXO03608.1\|1095769_1096888_-\|hypothetical-protein	gnl\|CDD\|377670	pfam06527, TniQ, TniQ. This family consists of several bacterial TniQ proteins. TniQ along with TniA and B is involved in the transposition of the mercury-resistance transposon Tn5053 which carries the mer operon. It has been suggested that the tni genes are involved in the dissemination of integrons.	1.8373e-17
CP031554.1\|AXO03620.1\|1109808_1111503_-\|iron-ABC-transporter-permease	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	1.34317e-127
CP031554.1\|AXO03616.1\|1105862_1107134_-\|murein-hydrolase-activator-EnvC	gnl\|CDD\|227278	COG4942, COG4942, Membrane-bound metallopeptidase [Cell division and chromosome partitioning].	1.43699e-139
CP031554.1\|AXO03621.1\|1111505_1112594_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.18207e-136

>CP031554.1|AXO03611.1|1099650_1100313_-|heteromeric-transposase-endonuclease-subunit-TnsA
MRKTHSFQQVRKIKPTWMSVSGHIPFRNGVSIPYESTLERDFLMYFTYLPSVDEIVSQPTTLPFVKNGITYTYTPDFFLSFTDGRKPMLIEVKPKAKWQKHWKEWKEKWKAAIRFCQENGYVFHVYDEDRIRHLALFNLNYVQRYKRIQHEQEDIDVILAQVKLMGNTTIDYLLSRFFAGSLYRMKGLQIIYHLLATKQLHCNWFLPLNEFTEVWGNNDE
>CP031554.1|AXO03610.1|1097732_1099661_-|transposase
MMSNSGFTEKRYHHRLDRGRIILQKGNIYLNREDGEQYELVDYMDEPSQLLVRNLNTRTTKVVSIHQLENFKMNERTDLSVDLTAISNEYWEKAQQKYEAIKPLLGMDQHRPYAVKARAEDVGVNPRTLYRWLQAYNSIGSIAGLVDQKRGWQQGNSRLTPEQDKLIVQVINEFYLHKQRPTTEQTIREIRRRCKIEKVESPSKETIRIRILHISEEERLRKRGQREKARNKFKPKPNSFPDADYPLSVVQIDHTPVDLIIVDSKYRKPIGRPFLTVAIDIYSRMIVGYYLSLDAPSVTSVAMCIARGILPKERLLLDLGLQGSEWNAFGYPVKVHVDNGPDFQALDLSKSCFAHGIHLEFRPMGRPEYGGHIERVIGTFMKEVHSLAGTTFSNIKERDSYDSEKEAIMTLDEFEKWLVHYIVNVYHKRVHSALGISPEQKWKIGIFGDENEVGCGYPQLPVDEQTLLLDFLPSITRTIQHNGVTIDGLRYYDVALNMYISDSDESGKSKEFLFRRDPRNISKIWFYDPKLKRYFPIPFANQAMPEMSIWEYREVRSRIANKGDKYINEQQVLDGLTEMREMVAESAQRTKKARRQAERQKMHKASKPIIETKVETNAVVPVVVTSNLLALDDESLSFGEVD
>CP031554.1|AXO03609.1|1096845_1097733_-|transposase
MQYEHVHEKFRHLVTADNQERIAFLDEPRWLGYGVAKDIMDNLVSLMNKPKRPRMLNLLIVGDSNNGKTTLIRRFFDLYGQAYIDSDSNAIYPILLAEAPPSANEKELYISLLERFYVPYKPTDTIAKLRYQTIHLFREFRVKMLIIDEFHSLLVGTPRLQRQVMNAIKMLCNELQIPIVGVGTRDAIRVLHTDPQHASRFDVAELPTWKLDKDFQKLLFQFQGILPLKKCSNLQSPELATKIHTISGGNLGNVHRLLTACAVEAITSGTEQITLDIIEKNSWVQPTQGFRKIIG
>CP031554.1|AXO03608.1|1095769_1096888_-|hypothetical-protein
MGTTNAGLPKNYRIKSGVIKTPLYSNESISSWLIRSALDCGTEPITFTGFYWNEWRLWTYDLDRGFEPISQHIYADINELSLNQQVNLVNHSLYSVLRPINGKNTLIKGQAKWVLSRGSRNRSFRVGQSYCPCCLEETPYLRNEWRFAWHFGCLKHKVLFESKCSCCGGLYQPHLLSAEKRQLNYCHQCGEKLQVITTPLNEVEIATMETLDNVFTTNSGECFGKCVDSQVYFAILRYFINFTRRAAIAKSTHSFSRFVEQCGISQVEICQTKTALAFEQLPVEERKNLLVNAGKILKLSSKDFIQAIKQSGITQKAFAFERYPTELDNLFKYAIEGKTTSRKTIINKPKTDSVLSLNRQWERLKRQLQIAV
>CP031554.1|AXO03607.1|1094351_1095809_-|hypothetical-protein
MGTTKTTITNCSMKITKIRSQNSCSICGKTPVTRKFREEYYCANCYAQWFKKKTCKSCGQLTRIHREGELCLECEKLTDCVRCGKTSGTFEIGMISRYGAVCSSCTRYFREEIECSECGKMTRDRYRSPVTNESVCLQCYRRYTFATCKNCRRYRKVHNQEKQLCKKCDEKLLSTCPKCKGEMPSGYGNVCPDCARRSLLFNMIRLNGHILRNKAVKTAYKKFIFWYMRKCGISVALHKGADFMRFFIDCDEIWQQIPDYAELVTHFKPNGLRANLTVLRWLLDTNQIIVDEALKDDLAELERIQALFNKLKESVPCIASYYQKLQRRCDEGKTSLKSVRLALQPAIDLISTNEVTDYPTQDQLNQYLVKKSGQTAAITGFINHLKSEYHRELEIDRKLIQQIKTKQLKKHCSQRLIELYKKSELTDNEQMELIYVVLYSLHSVEIKKPKQDKILLLDGVAYYRSEDRDYFLPQDIYQRINPQFS
>CP031554.1|AXO03606.1|1094009_1094234_-|tRNA-delta(2)-isopentenylpyrophosphate-transferase
MNSTNNKSTLSLKQQFKLWLEQEQKDGDMIILVGIPDILKRFDRRLAIIKGNQLEKRYLREWREAFRIDRKLFN
>CP031554.1|AXO03605.1|1092376_1093948_+|restriction-endonuclease
MKDIYCSFYTNSDLITNYMVHKIKLCNNDKVLEPSAGEGVFIDEILKSNIHLHIDALDINPEAVRVLNKKYSSYSSIKVRETDTLLDNELDLYDTSELWIKETDTLIDNEIDYFAKTGGYYDKVIGNPPYGAWQDHEKRSTLKKKYLGHYVKETYTLFLLRCLSVLKPKGLLSFIIPDTFMFLNMHSNLRKTLLTNAKIKEVLIFPSKFFPGVNFGYSNLSIITLEKCCKGDYQENEITIIKGLKNINELELLSKGLVDQIPNLNKLKIKQNEILNNPDCRFILTESEDKDMLINSKVKLGDIASVVTGFYTGNNVEFIKVLDKNVKGSKGYKIIKENEIFNSNSLEGIENVNYGYIPYIKRASAGKYFRGKDEWFVRWDKDAIAYYQTNKKSRFQNTTYYFKTGIGIPMVKSKSIKAFLMEDRVFDQSIVGLFPYEESKTLYILALMNSSVMNKYIHLINPTANNSANYIKQLPYIEPTESQMNIINKMVSELITLQKLDKLDKAEKIHDEVDKIISEIYSS
>CP031554.1|AXO03604.1|1091705_1092323_+|hypothetical-protein
MTFSRRIGELWEPFCKLAFKYSTKDLLLVEPLDFNQIKEDIKGNAINFIYKLPISFEDKNELIRLYETPWNLMGSGGIKLDLDLHFSQGNCYHNCDFKSGFSSNEKGNTNRLLLVGSIYNSLNQYMRNIIFVRQPEDQNNHYLQKLKHSGYWEVYCADDAYSVMAEFTGFNLKSWLENNADWANDMEQDFRRHLERNNLISYLTW
>CP031554.1|AXO03603.1|1088543_1089212_+|putative-tetracyline-resistance-transcriptional-regulator-TetC
MFLRLSRPHHHDTINILTVCYFKSIMENKNHQQENFKSTYQSLVNSARILFVEKGYQAVSIDEISGKALVTKGAFYHHFKNKKQLLSACYKQQLIMIDAYITTKTDLTNGWSALESIFEHYLDYIIDNNKNLIPIQEVMPIIGWNELEKISLEYITGKVNAIVSKLIQENQLKAYDDDVLKNLLNGWFMHIAIHAKNLKELADKKGQFIAIYRGFLLSLKDK
>CP031554.1|AXO03602.1|1086896_1088105_+|IS4-like-element-ISVsa5-family-transposase
MCELDILHDSLYQFCPELHLKRLNSLTLACHALLDCKTLTLTELGRNLPTKARTKHNIKRIDRLLGNRHLHKERLAVYRWHASFICSGNTMPIVLVDWSDIREQKRLMVLRASVALHGRSVTLYEKAFPLSEQCSKKAHDQFLADLASILPSNTTPLIVSDAGFKVPWYKSVEKLGWYWLSRVRGKVQYADLGAENWKPISNLHDMSSSHSKTLGYKRLTKSNPISCQILLYKSRSKGRKNQRSTRTHCHHPSPKIYSASAKEPWVLATNLPVEIRTPKQLVNIYSKRMQIEETFRDLKSPAYGLGLRHSRTSSSERFDIMLLIALMLQLTCWLAGVHAQKQGWDKHFQANTVRNRNVLSTVRLGMEVLRHSGYTITREDLLVAATLLAQNLFTHGYALGKL
>CP031554.1|AXO03613.1|1101648_1104210_+|hypothetical-protein
MNKSKKILGYILPLILPLYSYAESTELDVISVETEAFKEKDKVFLKQSASSTRTQFQTATQSLDSVLRSVPGSFTQIDKSSGTVSVNVRGGTGFGRVNTMIDGVSQTFYASSTDSGSRNSSTSQFGSLIDPGFLSRVEIDRGSFEGSHGANTLLGSAHFKTIGVKDLVAESRQLGFMGKYLWGSNATEPQVLGAVAFKQNFENERWLGLLYGFSERHLSQDYRIGGGRKVTESSIDLTGLDENDREQTDTSPFDATHVRQRPISHLAKLEYGDRYQQGTLSYRQYQTRVGGRSIRNNNYQFNYHLALPDISWLDFNLLLARNVSSQKYPEGTMIIGKTLLTPLIASNKADTFDVNNMFHFDLPFEATLKTRVGFHILKSRYFKNRDPSEELNINLEEGERTYDFDCLGLGCIRKSLGKATFQPNGKHNIITFYVDNHLSWKMFNLDYNINLSRYTLKGERLKYLPHYLSNMDNEINALTRKLRKGRSKDTKIQQQLLQLMSKRDDLKQHNCKEEEDGHEQCREVNFTLPDSSAGKMYNYSVTLSTHLHDLFTPFISYAKSHRAPNIREVFFSSVGDYGVNTNLKPETAKTIQFGINGYRDRLFSERDKLGYKVVYYNTHIKDFIYNSDNRQPLVAGKLIYLNDTNILHKNYSQRVKMTGIETEISYDMGNIYFNLTYAKQKNNQPVSFTDGSARTGGASNTNRLLQGFGASKISVLPESYGSLEIGTRFFDGKLDISTTAKYYGKSKRVLKQPLAIKSGDEKDTVKEQIRVTQDIPKQPIIFDLQISYEPIKNLVLKAEVQNVFDKRYINPLDANNDSASQSVFNIDLSDKTINVLNNFARGRTYVFTLSYQY
>CP031554.1|AXO03614.1|1104316_1105003_-|hypothetical-protein
MKQKYLFIASMALAGCGSMSESNKYWIQYKDIDQSVKEVSFWSREQFHSPSDVKGTVYQRDNLTHLATSTPLGEIYHIYDVNHIPMNVIFLDTKTQRSLNPQNAQDMAQLSKATQFDFYEFGKGRIAHAVFSAKTGLCQDFKSKRGVALKMATNYYTDDSYKGYYVSVIHAIIRHNGQHTDFAYTPAFSIADTKALAMTQALEKQDGERVAQMNLKEKVTLLTNIVCQ
>CP031554.1|AXO03615.1|1105023_1105866_-|divergent-polysaccharide-deacetylase-family-protein
MKTIGVKRVKSALLFGGFWISMALAQPAKLAIVIDDIGYHQKEDAQIYALPKEISVAIIPSAPHARQRNEQAYQQGRDILIHMPMQPLSHQRIEAGGLHVGMRQEDVQQRVQTAKAIVSHAIGMNNHMGSAATADAELMRKLMQELKVQDLFFLDSRTIGRSVAGKIAKEYGVQSLDRHIFLDDKDTYADVERQFQRAVHYAQKHGTAIAIGHPRKNTVAVLQAGLKHLPDNVQLVGMGRLWRSETGTAPKPLISLFNTMPAPTSSMPYQAVPMLRGIPQ
>CP031554.1|AXO03616.1|1105862_1107134_-|murein-hydrolase-activator-EnvC
MLYLINVILTEGFAMWLRLNNVKTRRKLTALCCGLLCMSVNVFANDLSKIQQQIKQQEQKIAEQKKAQQKLQSHLKNQETQINQVITQLRQTETDLKESRKMISDTEKQIQRLEKQEREQKQKLAEQLDSAYRSAANPSALERMLSEEAKNADRLKQYYAHMNQARLALIDDLKATQTQLAQEKATMIAQQKAQQSQLSQQKKQQQDLQKVQQERQSTLKQLNRNLSRDETRLETLRANENALRQEIQRAEQAARQQEQREREAYAQKKQAEEKKTQKPYQPTAQEKQLMASSSGLGKPNKQYAYPVSGKLLNSFGATQMGELRWKGMVIGANAGTAVKSIADGRVILANWLQGYGLMVIIKHGENDLSLYGYNQSVVVKEGQFVKAGQKIAEVGSSGGQSQSSLYFEIRRKGVAVNPIGWLK
>CP031554.1|AXO03617.1|1107274_1107958_+|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase
MELVFIRHGFSEWNAKNLFTGWRDVNLTERGIEEAKSAGKKLLEAGFEFDIAFTSVLTRAIKTCNIVLEESNQLWIPQVKNWRLNERHYGALQGLDKKATAEQYGDEQVHIWRRSYDISPPDLDPQDPHSAHNDRRYAHLPSDVVPDAENLKITLERVLPFWEDQIAPALLAGKRVLVTAHGNSLRALAKHIEGISDADIMDLEIPTGQPLVYKLDDNLKVVEKYYL
>CP031554.1|AXO03618.1|1108078_1108543_-|IS200/IS605-family-transposase
MASKSNDDSSLSHTRWNCKYHIVFIPKYRRKAIYGKLRVDIGGILRQLCHYKNVEIIEAYAMKEHIHMLLRIPPKLAVSSFMGYLKGKSSLMIFERHANLKYKYGNRNFWAKGYYVSTVGLNTKIVEEYIRNQEKEDMIQDNLSKKEYMDPFKG
>CP031554.1|AXO03619.1|1108728_1109787_-|ABC-transporter-ATP-binding-protein
MSYIQLNHVMKKFGDVIAIPDLSLSIEKGECFSMLGPSGCGKTTTLRMIAGFEDLDGGEIRVGDRLLSSKITNFYLPPEKRNFGMVFQAFAVWPHMTVYDNVAFPLTLKNVSRQEIEKRTNDALKHTNLLNVAQKSPDDLSGGGKQRVALARALALNPDVMLLDEPLSSLDPHLREEMRFEIKALQRKFGFSIIYVTHDQAEAMALSDRILVMRKGLIEQIDTPLNVYNNPSNKFVFNFIGLSNQLQVNLSPQGVSFAGLDGTFHIQPSPPIALVQQGKAILATRPSEIDFVNEGGVTGVVKRRSYLGEVIDYNIVVGDQELRVQKGRRDPGPKEGESCQLVFTRLHWYPVE
>CP031554.1|AXO03620.1|1109808_1111503_-|iron-ABC-transporter-permease
MAAVIQKSPFNVANAILALSIGILVIVVAVPVLLIFINSFWVNGQFNVTDVVNILKQKETYEALLNSLFIAVGVTIMSTIVGTFFAWLVTRTDLPYKGLMKVMFLVPFMLPSFIGALAWKMLLSPRAGYINRFFMDTFGLEEPIFNIYSYTGIMAVETMYLFPFVFIQVCGALERMDPTLEESARISGASLFTITRKITIPLVMPSIVSGALLIMLYSMAHFGTVAVLGVENGIFNIPTLIYERIHQSAGSFEAIRTGTVLATVLVVTAALIIWLQNKILNRGRFQIIAGKSFRPVEVKLRGLRMPLLFICVFYIAFTIVLPTVTIFIVGGLKTYGLPITWENLTFDNYKFILFDWQLTKDAIRNSVLLGLAAAVITMFAGVMISYVIVKMRVKGKGILEFLGMLPFSVPGSVIALGVILAWSGKFGINLYNTVWIILIAYIARYMAFSLKANSAALEQVHDSLVEAARACGASMWQSLKDIVVPLVRPGMIAAFFLIFLPALRELTVSVMLYGPSTRTIGVAIYTLNEDGETVYSAALAGIALIIIVFGQTVIKRYAEKKTQK
>CP031554.1|AXO03621.1|1111505_1112594_-|ABC-transporter-ATP-binding-protein
MATITFEKVSKAFGSNEVLKDLSLVVKDGECFTLLGPSGCGKTVLLRLLAGFDVPDSGRILIDEHVVSDPAEGIDIPPDQRSLGVVFQDYAVWPHMTVFDNIAYPLKLKDLDKALIQQQVMEVVNLVNLTGLEKRLPSQLSGGQQQRVALARALVAKPSLMLLDEPLNNLDANLREEMRFEIKELQKKLGITILYVTHDQEIALAISDRLAIMDKNGDIQQIGTPWEIYEKSANEMVFKFMGLANFIHVRYEEGQHFIGQGKQALQWQNLPAESGKLGCRPSDIILSKSGEGLKGKVARASFLGAVMDYMINIDGVSLRTEISTNKALQHDLMFQEGEDCYVNFHDLLWFTDNQQHVQQTRG
>CP031554.1|AXO03622.1|1112608_1113598_-|extracellular-solute-binding-protein
MKKTFSSALIALGLSMTIAGVAHANEKLIVYTSMKESLIGALKTKFNEKHPDIAMDYQSAGAGKLMAKIAAEKESGQIMADVIWTSEVPDFFKMKANGMLDAYVSPEVEHIVNPIPDFDGSFTPIRLGTLGIAYNTRFVKEPPTSWDDITGAKYKGAFGIANPALSGTAYMSVALLKSTFGWEFFEKIKANKGKVGKGSGQVVDDTASGDLLASLAVDYITNDKIKKGAQLKLVYPKEMLVIPSPAAIFKGTKNPAAAKKFIDFLLSEEAQHIIAHEGTLPVRKGVATLEGMPTVEDAISRAIPIDYQAILTEKEEIVKKFTQILQGRQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP031554_3	3.19\|766632\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766632-766663	32	CP031554.1	999791-999822	0	1.0
CP031554_3	3.20\|766692\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766692-766723	32	CP031554.1	889425-889456	0	1.0
CP031554_3	3.21\|766752\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766752-766783	32	CP031554.1	1636661-1636692	2	0.938

1. spacer 3.19|766632|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to position: 999791-999822, mismatch: 0, identity: 1.0

tacgccattatggcgactgacttccgcgataa	CRISPR spacer
tacgccattatggcgactgacttccgcgataa	Protospacer
********************************

2. spacer 3.20|766692|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to position: 889425-889456, mismatch: 0, identity: 1.0

acttgtgcaagggttgtgtgttcataggcttt	CRISPR spacer
acttgtgcaagggttgtgtgttcataggcttt	Protospacer
********************************

3. spacer 3.21|766752|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to position: 1636661-1636692, mismatch: 2, identity: 0.938

taaaattaaaactatcgtcgcttgcttgtagc	CRISPR spacer
taaaattataactgtcgtcgcttgcttgtagc	Protospacer
******** ****.******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP031554_3	3.20\|766692\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766692-766723	32	MH238466	Pasteurella phage AFS-2018a, complete genome	26881-26912	0	1.0
CP031554_3	3.22\|766812\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766812-766843	32	MH238467	Pasteurella phage Pm86, complete genome	42524-42555	0	1.0
CP031554_3	3.1\|765552\|32\|CP031554\|CRISPRCasFinder,CRT	765552-765583	32	MH238467	Pasteurella phage Pm86, complete genome	42601-42632	1	0.969
CP031554_3	3.4\|765732\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765732-765763	32	MH238466	Pasteurella phage AFS-2018a, complete genome	23770-23801	1	0.969
CP031554_1	1.14\|209943\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209943-209974	32	NC_003315	Haemophilus phage HP2, complete genome	26899-26930	2	0.938
CP031554_1	1.14\|209943\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209943-209974	32	AY027935	Haemophilus influenzae phage HP2, complete genome	26899-26930	2	0.938
CP031554_3	3.3\|765672\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765672-765703	32	NC_008193	Pasteurella phage F108, complete genome	11445-11476	2	0.938
CP031554_3	3.3\|765672\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765672-765703	32	DQ114220	Bacteriophage F108, complete genome	11445-11476	2	0.938
CP031554_3	3.9\|766032\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766032-766063	32	MH238467	Pasteurella phage Pm86, complete genome	42843-42874	2	0.938
CP031554_3	3.21\|766752\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766752-766783	32	MH238467	Pasteurella phage Pm86, complete genome	48883-48914	2	0.938
CP031554_1	1.14\|209943\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209943-209974	32	U24159	Bacteriophage HP1 strain HP1c1, complete genome	27719-27750	3	0.906
CP031554_1	1.14\|209943\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209943-209974	32	NC_001697	Haemophilus phage HP1, complete genome	27719-27750	3	0.906
CP031554_1	1.12\|209823\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209823-209854	32	NZ_CP017756	Cupriavidus malaysiensis strain USMAA1020 isolate pure plasmid unnamed1, complete sequence	73488-73519	5	0.844
CP031554_3	3.7\|765912\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765912-765943	32	HQ110084	Erwinia phage ENT90, complete genome	19091-19122	5	0.844
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NZ_KX086582	Staphylococcus aureus strain WBG1024 plasmid pWBG637, complete sequence	25794-25825	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NZ_KF831355	Staphylococcus aureus strain A960649 plasmid pBU108a, complete sequence	23170-23201	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NZ_AP018563	Staphylococcus argenteus strain 58113 plasmid p1, complete sequence	18411-18442	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NC_013327	Staphylococcus aureus plasmid pWBG749, complete sequence	26168-26199	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	CP030569	Staphylococcus aureus strain ER01892.3 plasmid unnamed1, complete sequence	12940-12971	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	CP030458	Staphylococcus aureus strain ER04013.3 plasmid unnamed1, complete sequence	15652-15683	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NZ_AP017923	Staphylococcus aureus strain JP02758 plasmid pJP080, complete sequence	17835-17866	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NC_013325	Staphylococcus aureus plasmid pWBG745, complete sequence	13088-13119	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	CP030696	Staphylococcus aureus strain ER01532.3 plasmid unnamed1, complete sequence	28191-28222	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	CP030710	Staphylococcus aureus strain ER01174.3 plasmid unnamed1, complete sequence	7547-7578	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NZ_CP012757	Staphylococcus aureus subsp. aureus strain JS395 plasmid, complete sequence	37721-37752	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NZ_CP042004	Staphylococcus aureus strain B3-14B plasmid pSALNT46, complete sequence	11471-11502	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NZ_CP047857	Staphylococcus aureus strain UP_1435 plasmid unnamed1, complete sequence	26882-26913	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NZ_CP012594	Staphylococcus aureus strain HOU1444-VR plasmid pVR-MSSA_01, complete sequence	9160-9191	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NZ_MH587575	Staphylococcus aureus strain WBG4880 plasmid pWBG637, complete sequence	17922-17953	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	NZ_MH587574	Staphylococcus aureus strain WBG10514 plasmid pWBG731, complete sequence	17842-17873	6	0.812
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	CP030603	Staphylococcus aureus strain ER00484.3 plasmid unnamed1, complete sequence	34556-34587	6	0.812
CP031554_3	3.16\|766452\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766452-766483	32	NZ_CP045351	Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence	521041-521072	6	0.812
CP031554_1	1.11\|209763\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209763-209794	32	NZ_CP046163	Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence	465830-465861	7	0.781
CP031554_1	1.11\|209763\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209763-209794	32	NZ_CP046066	Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence	650120-650151	7	0.781
CP031554_1	1.11\|209763\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209763-209794	32	NZ_CP045356	Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence	1110688-1110719	7	0.781
CP031554_1	1.14\|209943\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209943-209974	32	MN693155	Marine virus AFVG_25M94, complete genome	42117-42148	7	0.781
CP031554_1	1.13\|209883\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209883-209914	32	MN694758	Marine virus AFVG_250M853, complete genome	27038-27069	8	0.75
CP031554_1	1.13\|209883\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209883-209914	32	MN694774	Marine virus AFVG_250M941, complete genome	26488-26519	8	0.75
CP031554_1	1.13\|209883\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209883-209914	32	MN694077	Marine virus AFVG_250M852, complete genome	27041-27072	8	0.75
CP031554_1	1.13\|209883\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209883-209914	32	MN693487	Marine virus AFVG_25M100, complete genome	6473-6504	8	0.75
CP031554_1	1.13\|209883\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209883-209914	32	MN694586	Marine virus AFVG_250M370, complete genome	8206-8237	8	0.75
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	MK905543	Vibrio phage USC-1, complete genome	55483-55514	8	0.75
CP031554_3	3.2\|765612\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765612-765643	32	MK358448	Vibrio phage 5, complete genome	209261-209292	8	0.75
CP031554_3	3.21\|766752\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766752-766783	32	AY328852	Vibrio parahaemolyticus phage VP16T, partial sequence	41690-41721	8	0.75
CP031554_1	1.7\|209523\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209523-209554	32	LN846932	Carnobacterium maltaromaticum strain LMA28 LMA_pa plamid, complete genome	1949-1980	9	0.719
CP031554_3	3.7\|765912\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765912-765943	32	NZ_CP037949	Erwinia sp. QL-Z3 plasmid unnamed1, complete sequence	20626-20657	9	0.719
CP031554_3	3.7\|765912\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765912-765943	32	NC_014305	Erwinia billingiae Eb661 plasmid pEB170, complete sequence	99511-99542	9	0.719
CP031554_3	3.8\|765972\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765972-766003	32	NZ_CP039495	Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000669 plasmid pCFSAN000669_2, complete sequence	22879-22910	9	0.719
CP031554_3	3.8\|765972\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765972-766003	32	NC_011802	Salmonella enterica bacteriophage SE1, complete genome	13842-13873	9	0.719
CP031554_3	3.8\|765972\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765972-766003	32	CP051278	Salmonella phage ST-87, complete genome	24650-24681	9	0.719
CP031554_3	3.8\|765972\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765972-766003	32	CP051288	Salmonella phage ST-29, complete genome	37493-37524	9	0.719
CP031554_3	3.8\|765972\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765972-766003	32	CP051285	Salmonella phage ST-32, complete genome	30587-30618	9	0.719
CP031554_3	3.8\|765972\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765972-766003	32	MH370387	Salmonella phage S149, complete genome	14295-14326	9	0.719
CP031554_3	3.8\|765972\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765972-766003	32	MG407615	Salmonella phage Bp96115, partial genome	4214-4245	9	0.719
CP031554_3	3.8\|765972\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765972-766003	32	NC_042346	Salmonella virus BTP1 genome assembly, chromosome: BTP1	29932-29963	9	0.719
CP031554_3	3.8\|765972\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765972-766003	32	NC_014900	Salmonella phage ST160, complete genome	13910-13941	9	0.719
CP031554_3	3.8\|765972\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	765972-766003	32	NC_005841	Enterobacteria phage ST104 DNA, complete genome	14296-14327	9	0.719
CP031554_3	3.18\|766572\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766572-766603	32	JX094500	Cronobacter phage CR5, complete genome	210741-210772	9	0.719
CP031554_3	3.22\|766812\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766812-766843	32	NZ_CP012702	Sphingopyxis macrogoltabida strain EY-1 isolate activated sludge plasmid 2, complete sequence	56918-56949	9	0.719
CP031554_3	3.22\|766812\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766812-766843	32	NZ_CP033227	Sphingobium yanoikuyae strain SJTF8 plasmid pF1, complete sequence	447275-447306	9	0.719
CP031554_1	1.6\|209463\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209463-209494	32	CP011076	Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence	505837-505868	10	0.688
CP031554_1	1.12\|209823\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209823-209854	32	NZ_CP025547	Mycobacterium paragordonae strain 49061 plasmid unnamed1, complete sequence	284092-284123	10	0.688
CP031554_1	1.13\|209883\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209883-209914	32	NZ_CP026928	Agrobacterium tumefaciens strain 1D1609 plasmid pAt1D1609b, complete sequence	5680-5711	10	0.688
CP031554_1	1.13\|209883\|32\|CP031554\|PILER-CR,CRISPRCasFinder,CRT	209883-209914	32	GU943040	Uncultured phage MedDCM-OCT-S09-C28 genomic sequence	16896-16927	10	0.688
CP031554_3	3.11\|766152\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766152-766183	32	MH271312	Microbacterium phage RobsFeet, complete genome	44909-44940	10	0.688
CP031554_3	3.11\|766152\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766152-766183	32	MK524510	Microbacterium phage Fireman, complete genome	45329-45360	10	0.688
CP031554_3	3.22\|766812\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766812-766843	32	NZ_CP023452	Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p3, complete sequence	33336-33367	10	0.688
CP031554_3	3.22\|766812\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766812-766843	32	NZ_CP009296	Novosphingobium pentaromativorans US6-1 plasmid pLA2, complete sequence	25608-25639	10	0.688
CP031554_3	3.22\|766812\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766812-766843	32	NZ_CP022749	Sphingobium hydrophobicum strain C1 plasmid p3, complete sequence	36365-36396	10	0.688
CP031554_3	3.22\|766812\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766812-766843	32	NZ_CP033229	Sphingobium yanoikuyae strain SJTF8 plasmid pF3, complete sequence	14157-14188	10	0.688
CP031554_3	3.22\|766812\|32\|CP031554\|CRISPRCasFinder,CRT,PILER-CR	766812-766843	32	NZ_CP015989	Sphingobium sp. EP60837 plasmid pEP2, complete sequence	154369-154400	10	0.688

1. spacer 3.20|766692|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MH238466 (Pasteurella phage AFS-2018a, complete genome) position: , mismatch: 0, identity: 1.0

acttgtgcaagggttgtgtgttcataggcttt	CRISPR spacer
acttgtgcaagggttgtgtgttcataggcttt	Protospacer
********************************

2. spacer 3.22|766812|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MH238467 (Pasteurella phage Pm86, complete genome) position: , mismatch: 0, identity: 1.0

actagcggaggctcaacaatgacggaaggtaa	CRISPR spacer
actagcggaggctcaacaatgacggaaggtaa	Protospacer
********************************

3. spacer 3.1|765552|32|CP031554|CRISPRCasFinder,CRT matches to MH238467 (Pasteurella phage Pm86, complete genome) position: , mismatch: 1, identity: 0.969

accaatctgataatcgagccaagatcgcttta	CRISPR spacer
accaatctgataatcgagccaaaatcgcttta	Protospacer
**********************.*********

4. spacer 3.4|765732|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MH238466 (Pasteurella phage AFS-2018a, complete genome) position: , mismatch: 1, identity: 0.969

gtatgagttcggcatttgcagagcttaaagct	CRISPR spacer
gcatgagttcggcatttgcagagcttaaagct	Protospacer
*.******************************

5. spacer 1.14|209943|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to NC_003315 (Haemophilus phage HP2, complete genome) position: , mismatch: 2, identity: 0.938

ctgtatttctaataaatcggtcttcagctaat	CRISPR spacer
atgcatttctaataaatcggtcttcagctaat	Protospacer
 **.****************************

6. spacer 1.14|209943|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to AY027935 (Haemophilus influenzae phage HP2, complete genome) position: , mismatch: 2, identity: 0.938

ctgtatttctaataaatcggtcttcagctaat	CRISPR spacer
atgcatttctaataaatcggtcttcagctaat	Protospacer
 **.****************************

7. spacer 3.3|765672|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NC_008193 (Pasteurella phage F108, complete genome) position: , mismatch: 2, identity: 0.938

agtgtaattccgctccgttgcttaaaataatc	CRISPR spacer
agtgtaattccgcgccattgcttaaaataatc	Protospacer
************* **.***************

8. spacer 3.3|765672|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to DQ114220 (Bacteriophage F108, complete genome) position: , mismatch: 2, identity: 0.938

agtgtaattccgctccgttgcttaaaataatc	CRISPR spacer
agtgtaattccgcgccattgcttaaaataatc	Protospacer
************* **.***************

9. spacer 3.9|766032|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MH238467 (Pasteurella phage Pm86, complete genome) position: , mismatch: 2, identity: 0.938

atgacttttggggagctatcggcatagtgctt	CRISPR spacer
atgacttttggggtgctatcggtatagtgctt	Protospacer
************* ********.*********

10. spacer 3.21|766752|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MH238467 (Pasteurella phage Pm86, complete genome) position: , mismatch: 2, identity: 0.938

taaaattaaaactatcgtcgcttgcttgtagc	CRISPR spacer
taaaattaaaactgtcgtcgctagcttgtagc	Protospacer
*************.******** *********

11. spacer 1.14|209943|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to U24159 (Bacteriophage HP1 strain HP1c1, complete genome) position: , mismatch: 3, identity: 0.906

ctgtatttctaataaatcggtcttcagctaat	CRISPR spacer
ctgtatttctaataaatcggtcttccgcaagt	Protospacer
************************* ** *.*

12. spacer 1.14|209943|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to NC_001697 (Haemophilus phage HP1, complete genome) position: , mismatch: 3, identity: 0.906

ctgtatttctaataaatcggtcttcagctaat	CRISPR spacer
ctgtatttctaataaatcggtcttccgcaagt	Protospacer
************************* ** *.*

13. spacer 1.12|209823|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017756 (Cupriavidus malaysiensis strain USMAA1020 isolate pure plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.844

agggcatg-gattttcggcactggaaatcgaat	CRISPR spacer
-gggcaagccattttcggcaccagaaatcgaat	Protospacer
 ***** *  ***********..**********

14. spacer 3.7|765912|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to HQ110084 (Erwinia phage ENT90, complete genome) position: , mismatch: 5, identity: 0.844

cgggtgcgcaaatggtttgcgacaaaaggcga	CRISPR spacer
cgcatccgcaaaaagtttgcgacaaaaggcga	Protospacer
** .* ****** .******************

15. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KX086582 (Staphylococcus aureus strain WBG1024 plasmid pWBG637, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

16. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KF831355 (Staphylococcus aureus strain A960649 plasmid pBU108a, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

17. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP018563 (Staphylococcus argenteus strain 58113 plasmid p1, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

18. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NC_013327 (Staphylococcus aureus plasmid pWBG749, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

19. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to CP030569 (Staphylococcus aureus strain ER01892.3 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

20. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to CP030458 (Staphylococcus aureus strain ER04013.3 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

21. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP017923 (Staphylococcus aureus strain JP02758 plasmid pJP080, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

22. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NC_013325 (Staphylococcus aureus plasmid pWBG745, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

23. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to CP030696 (Staphylococcus aureus strain ER01532.3 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

24. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to CP030710 (Staphylococcus aureus strain ER01174.3 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

25. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012757 (Staphylococcus aureus subsp. aureus strain JS395 plasmid, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

26. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP042004 (Staphylococcus aureus strain B3-14B plasmid pSALNT46, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

27. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP047857 (Staphylococcus aureus strain UP_1435 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

28. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012594 (Staphylococcus aureus strain HOU1444-VR plasmid pVR-MSSA_01, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

29. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH587575 (Staphylococcus aureus strain WBG4880 plasmid pWBG637, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

30. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MH587574 (Staphylococcus aureus strain WBG10514 plasmid pWBG731, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

31. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to CP030603 (Staphylococcus aureus strain ER00484.3 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.812

-aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
taacggtag-aaacagaagaatttgaatatgac	Protospacer
 ** .*.** ************* *** *****

32. spacer 3.16|766452|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045351 (Vibrio sp. THAF100 plasmid pTHAF100_a, complete sequence) position: , mismatch: 6, identity: 0.812

aaaggcaatatgcgacaaattccag---agatttt	CRISPR spacer
aaatgcaatatgcgacaaatcccaagtcagat---	Protospacer
*** ****************.***.   ****

33. spacer 1.11|209763|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046163 (Vibrio sp. THAF191c plasmid pTHAF191c_b, complete sequence) position: , mismatch: 7, identity: 0.781

gattgtcagccgttagttgaacacgtcattat	CRISPR spacer
tatgttcagccgatagttgaacacgtcagaaa	Protospacer
 **  ******* ***************  *

34. spacer 1.11|209763|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046066 (Vibrio sp. THAF191d plasmid pTHAF191d_b, complete sequence) position: , mismatch: 7, identity: 0.781

gattgtcagccgttagttgaacacgtcattat	CRISPR spacer
tatgttcagccgatagttgaacacgtcagaaa	Protospacer
 **  ******* ***************  *

35. spacer 1.11|209763|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045356 (Vibrio sp. THAF64 plasmid pTHAF64_a, complete sequence) position: , mismatch: 7, identity: 0.781

gattgtcagccgttagttgaacacgtcattat	CRISPR spacer
tatgttcagccgatagttgaacacgtcagaaa	Protospacer
 **  ******* ***************  *

36. spacer 1.14|209943|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to MN693155 (Marine virus AFVG_25M94, complete genome) position: , mismatch: 7, identity: 0.781

ctgtatttctaataaatcggtct-tcagctaat	CRISPR spacer
ctgtatttcttataaattggtctaacaacgta-	Protospacer
********** ******.*****  **.*  *

37. spacer 1.13|209883|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to MN694758 (Marine virus AFVG_250M853, complete genome) position: , mismatch: 8, identity: 0.75

ttttcaatgaccgttaaatcttctagtgtttc	CRISPR spacer
cctccctcgacctttaaatcttctagtgtttt	Protospacer
..*.*  .**** ******************.

38. spacer 1.13|209883|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to MN694774 (Marine virus AFVG_250M941, complete genome) position: , mismatch: 8, identity: 0.75

ttttcaatgaccgttaaatcttctagtgtttc	CRISPR spacer
cctccctcgacctttaaatcttctagtgtttt	Protospacer
..*.*  .**** ******************.

39. spacer 1.13|209883|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to MN694077 (Marine virus AFVG_250M852, complete genome) position: , mismatch: 8, identity: 0.75

ttttcaatgaccgttaaatcttctagtgtttc	CRISPR spacer
cctccctcgacctttaaatcttctagtgtttt	Protospacer
..*.*  .**** ******************.

40. spacer 1.13|209883|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to MN693487 (Marine virus AFVG_25M100, complete genome) position: , mismatch: 8, identity: 0.75

ttttcaatgaccgttaaatcttctagtgtttc	CRISPR spacer
cctccctcgacctttaaatcttctagtgtttt	Protospacer
..*.*  .**** ******************.

41. spacer 1.13|209883|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to MN694586 (Marine virus AFVG_250M370, complete genome) position: , mismatch: 8, identity: 0.75

ttttcaatgaccgttaaatcttctagtgtttc	CRISPR spacer
cctccctcgacctttaaatcttctagtgtttt	Protospacer
..*.*  .**** ******************.

42. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MK905543 (Vibrio phage USC-1, complete genome) position: , mismatch: 8, identity: 0.75

aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
agtctgaggaaacagaagaattggaagacgat	Protospacer
*.    **.*******************.**.

43. spacer 3.2|765612|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MK358448 (Vibrio phage 5, complete genome) position: , mismatch: 8, identity: 0.75

aagagcagaaaacagaagaattggaagatgac	CRISPR spacer
agtctgaggaaacagaagaattggaagacgat	Protospacer
*.    **.*******************.**.

44. spacer 3.21|766752|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to AY328852 (Vibrio parahaemolyticus phage VP16T, partial sequence) position: , mismatch: 8, identity: 0.75

taaaattaaaactatcgtcgcttgcttgtagc	CRISPR spacer
gttaagcacaaccatcgccgcttgcttgtagc	Protospacer
   ** .* ***.****.**************

45. spacer 1.7|209523|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to LN846932 (Carnobacterium maltaromaticum strain LMA28 LMA_pa plamid, complete genome) position: , mismatch: 9, identity: 0.719

ttaattcatctgttcaagcgcaaggtgggctt	CRISPR spacer
aaaatacatctgttaaagcgcaaggaaagcaa	Protospacer
  *** ******** ********** ..**

46. spacer 3.7|765912|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP037949 (Erwinia sp. QL-Z3 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

cgggtgcgcaaatggtttgcgacaaaaggcga	CRISPR spacer
atcattcgctgatggtttgcgacaaaaggccg	Protospacer
   .* *** .******************* .

47. spacer 3.7|765912|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NC_014305 (Erwinia billingiae Eb661 plasmid pEB170, complete sequence) position: , mismatch: 9, identity: 0.719

cgggtgcgcaaatggtttgcgacaaaaggcga	CRISPR spacer
atcattcgctgatggtttgcgacaaaaggccg	Protospacer
   .* *** .******************* .

48. spacer 3.8|765972|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039495 (Salmonella enterica subsp. enterica serovar Bareilly str. CFSAN000669 plasmid pCFSAN000669_2, complete sequence) position: , mismatch: 9, identity: 0.719

aactataataaaaaaggctgttgccattgcta	CRISPR spacer
caaagcaatacaaaaagctgttgccattgcag	Protospacer
 *  ..**** ****.************** .

49. spacer 3.8|765972|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NC_011802 (Salmonella enterica bacteriophage SE1, complete genome) position: , mismatch: 9, identity: 0.719

aactataataaaaaaggctgttgccattgcta	CRISPR spacer
caaagcaatacaaaaagctgttgccattgcag	Protospacer
 *  ..**** ****.************** .

50. spacer 3.8|765972|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to CP051278 (Salmonella phage ST-87, complete genome) position: , mismatch: 9, identity: 0.719

aactataataaaaaaggctgttgccattgcta	CRISPR spacer
caaagcaatacaaaaagctgttgccattgcag	Protospacer
 *  ..**** ****.************** .

51. spacer 3.8|765972|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to CP051288 (Salmonella phage ST-29, complete genome) position: , mismatch: 9, identity: 0.719

aactataataaaaaaggctgttgccattgcta	CRISPR spacer
caaagcaatacaaaaagctgttgccattgcag	Protospacer
 *  ..**** ****.************** .

52. spacer 3.8|765972|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to CP051285 (Salmonella phage ST-32, complete genome) position: , mismatch: 9, identity: 0.719

aactataataaaaaaggctgttgccattgcta	CRISPR spacer
caaagcaatacaaaaagctgttgccattgcag	Protospacer
 *  ..**** ****.************** .

53. spacer 3.8|765972|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MH370387 (Salmonella phage S149, complete genome) position: , mismatch: 9, identity: 0.719

aactataataaaaaaggctgttgccattgcta	CRISPR spacer
caaagcaatacaaaaagctgttgccattgcag	Protospacer
 *  ..**** ****.************** .

54. spacer 3.8|765972|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MG407615 (Salmonella phage Bp96115, partial genome) position: , mismatch: 9, identity: 0.719

aactataataaaaaaggctgttgccattgcta	CRISPR spacer
caaagcaatacaaaaagctgttgccattgcag	Protospacer
 *  ..**** ****.************** .

55. spacer 3.8|765972|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NC_042346 (Salmonella virus BTP1 genome assembly, chromosome: BTP1) position: , mismatch: 9, identity: 0.719

aactataataaaaaaggctgttgccattgcta	CRISPR spacer
caaagcaatacaaaaagctgttgccattgcag	Protospacer
 *  ..**** ****.************** .

56. spacer 3.8|765972|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NC_014900 (Salmonella phage ST160, complete genome) position: , mismatch: 9, identity: 0.719

aactataataaaaaaggctgttgccattgcta	CRISPR spacer
caaagcaatacaaaaagctgttgccattgcag	Protospacer
 *  ..**** ****.************** .

57. spacer 3.8|765972|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NC_005841 (Enterobacteria phage ST104 DNA, complete genome) position: , mismatch: 9, identity: 0.719

aactataataaaaaaggctgttgccattgcta	CRISPR spacer
caaagcaatacaaaaagctgttgccattgcag	Protospacer
 *  ..**** ****.************** .

58. spacer 3.18|766572|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to JX094500 (Cronobacter phage CR5, complete genome) position: , mismatch: 9, identity: 0.719

ctcgggataatcatccactgctcacctgaaat	CRISPR spacer
agcgggataatcatcgacttctcaccgccggt	Protospacer
  ************* *** ******   ..*

59. spacer 3.22|766812|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012702 (Sphingopyxis macrogoltabida strain EY-1 isolate activated sludge plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.719

actagcggaggctcaacaatgacggaaggtaa	CRISPR spacer
atcgtggcaggctcaaaactgacggaaggtag	Protospacer
*...  * ******** * ************.

60. spacer 3.22|766812|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033227 (Sphingobium yanoikuyae strain SJTF8 plasmid pF1, complete sequence) position: , mismatch: 9, identity: 0.719

actagcggaggctcaacaatgacggaaggtaa	CRISPR spacer
atcgtggcaggctcaaaactgacggaaggtag	Protospacer
*...  * ******** * ************.

61. spacer 1.6|209463|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to CP011076 (Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.688

gtagtgaatcttgcggataaacgtagcttaaa	CRISPR spacer
ctctacaatcttgcggataaccgtggctttgt	Protospacer
 *    ************** ***.**** .

62. spacer 1.12|209823|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025547 (Mycobacterium paragordonae strain 49061 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.688

agggcatggattttcggcactggaaatcgaat	CRISPR spacer
tcggcatggattttcggggctggaacagcagc	Protospacer
  *************** .******    *..

63. spacer 1.13|209883|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026928 (Agrobacterium tumefaciens strain 1D1609 plasmid pAt1D1609b, complete sequence) position: , mismatch: 10, identity: 0.688

ttttcaatgaccgttaaatcttctagtgtttc	CRISPR spacer
atttcgatgacggttaaatcttcttgccgcga	Protospacer
 ****.***** ************ *.  .

64. spacer 1.13|209883|32|CP031554|PILER-CR,CRISPRCasFinder,CRT matches to GU943040 (Uncultured phage MedDCM-OCT-S09-C28 genomic sequence) position: , mismatch: 10, identity: 0.688

ttttcaatgaccgttaaatcttctagtgtttc	CRISPR spacer
accgcctgaaccgttaaaagttctagtgtttc	Protospacer
 .. *   .*********  ************

65. spacer 3.11|766152|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MH271312 (Microbacterium phage RobsFeet, complete genome) position: , mismatch: 10, identity: 0.688

acgtgatgacgtgctcatctgcgctgtggctt	CRISPR spacer
ctccgccaacgtgctcatctgggccgtggctc	Protospacer
 . .* ..************* **.******.

66. spacer 3.11|766152|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to MK524510 (Microbacterium phage Fireman, complete genome) position: , mismatch: 10, identity: 0.688

acgtgatgacgtgctcatctgcgctgtggctt	CRISPR spacer
ctccgccaacgtgctcatctgggccgtggctc	Protospacer
 . .* ..************* **.******.

67. spacer 3.22|766812|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP023452 (Rhizorhabdus dicambivorans strain Ndbn-20 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.688

actagcggaggctcaacaatgacggaaggtaa	CRISPR spacer
atcgtgacaggctcaaaactgacggaaggtag	Protospacer
*...  . ******** * ************.

68. spacer 3.22|766812|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009296 (Novosphingobium pentaromativorans US6-1 plasmid pLA2, complete sequence) position: , mismatch: 10, identity: 0.688

actagcggaggctcaacaatgacggaaggtaa	CRISPR spacer
atcgtgacaggctcaaaactgacggaaggtag	Protospacer
*...  . ******** * ************.

69. spacer 3.22|766812|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP022749 (Sphingobium hydrophobicum strain C1 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.688

actagcggaggctcaacaatgacggaaggtaa	CRISPR spacer
atcgtgacaggctcaaaactgacggaaggtag	Protospacer
*...  . ******** * ************.

70. spacer 3.22|766812|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033229 (Sphingobium yanoikuyae strain SJTF8 plasmid pF3, complete sequence) position: , mismatch: 10, identity: 0.688

actagcggaggctcaacaatgacggaaggtaa	CRISPR spacer
atcgtgacaggctcaaaactgacggaaggtag	Protospacer
*...  . ******** * ************.

71. spacer 3.22|766812|32|CP031554|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015989 (Sphingobium sp. EP60837 plasmid pEP2, complete sequence) position: , mismatch: 10, identity: 0.688

actagcggaggctcaacaatgacggaaggtaa	CRISPR spacer
atcgtgacaggctcaaaactgacggaaggtag	Protospacer
*...  . ******** * ************.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

99536 : 135329

Pseudomonas_phage(54.84%)

transposase,tail,capsid

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO02737.1\|99536_100382_-	hypothetical protein	F6MIM2	Haemophilus_phage	2.4e-101	62.4
AXO02738.1\|100533_100794_-	hypothetical protein	B7SDP6	Haemophilus_phage	5.8e-19	57.3
AXO02739.1\|100859_103649_-\|tail	phage tail protein	A0A2D1GNP9	Pseudomonas_phage	2.0e-181	46.0
AXO02740.1\|103648_103849_-	hypothetical protein	A0A2D2W288	Stenotrophomonas_phage	1.2e-08	45.8
AXO02741.1\|103852_104104_-	hypothetical protein	A0A2D1GNV4	Pseudomonas_phage	4.6e-21	59.2
AXO02742.1\|104120_104930_-	DUF2163 domain-containing protein	A0A2D1GNT2	Pseudomonas_phage	1.7e-77	50.5
AXO02743.1\|104943_106623_-\|tail	phage tail protein	J9STL4	Pseudomonas_phage	4.4e-91	38.6
AXO02744.1\|106630_107593_-	hypothetical protein	NA	NA	NA	NA
AXO02745.1\|107594_108587_-	hypothetical protein	A0A2D1GMZ0	Marinobacter_phage	5.2e-23	27.5
AXO02746.1\|108596_111944_-\|tail	phage tail protein	A0A2D1GNK1	Pseudomonas_phage	3.8e-118	32.5
AXO02747.1\|111956_112172_+	hypothetical protein	NA	NA	NA	NA
AXO04811.1\|112202_112382_-	hypothetical protein	NA	NA	NA	NA
AXO02748.1\|112381_112807_-	hypothetical protein	A0A2D1GNY5	Pseudomonas_phage	3.0e-20	40.4
AXO02749.1\|112867_113614_-	hypothetical protein	A0A2D1GNQ7	Pseudomonas_phage	1.2e-59	49.2
AXO02750.1\|113606_113867_-	hypothetical protein	NA	NA	NA	NA
AXO02751.1\|113863_114310_-	hypothetical protein	A0A0S4L2X9	Pseudomonas_phage	1.5e-14	30.9
AXO02752.1\|114309_114816_-	DUF1320 domain-containing protein	Q5ZQX5	Pseudomonas_phage	1.6e-28	42.1
AXO02753.1\|114825_115749_-\|capsid	phage capsid protein	A0A0S4L2T7	Pseudomonas_phage	1.8e-102	60.7
AXO02754.1\|115809_116175_-	hypothetical protein	NA	NA	NA	NA
AXO02755.1\|116171_117173_-	peptidase	Q5ZQY0	Pseudomonas_phage	8.0e-40	54.6
AXO02756.1\|117390_117891_-	phage virion morphogenesis protein	Q5ZQY1	Pseudomonas_phage	3.1e-32	41.7
AXO02757.1\|117988_119227_-	hypothetical protein	J9STS2	Pseudomonas_phage	2.3e-105	47.2
AXO02758.1\|119210_120734_-	DUF935 family protein	Q5ZQY4	Pseudomonas_phage	2.5e-149	53.5
AXO02759.1\|120736_122353_-	hypothetical protein	Q6QIC1	Burkholderia_phage	2.9e-185	64.6
AXO02760.1\|122352_122892_-	DUF3486 family protein	A4JWJ3	Burkholderia_virus	4.0e-46	51.7
AXO02761.1\|122903_123209_-	hypothetical protein	A0A2H4JGU5	uncultured_Caudovirales_phage	8.7e-22	53.0
AXO02762.1\|123210_123561_-	hypothetical protein	Q6QIC4	Burkholderia_phage	5.3e-07	33.6
AXO04812.1\|123657_123909_-	hypothetical protein	NA	NA	NA	NA
AXO02763.1\|124088_124688_-	lytic transglycosylase domain-containing protein	J9SHG5	Pseudomonas_phage	2.7e-59	55.7
AXO02764.1\|124689_125061_-	hypothetical protein	Q6QIC8	Burkholderia_phage	2.6e-20	53.2
AXO02765.1\|125302_125542_-	hypothetical protein	NA	NA	NA	NA
AXO02766.1\|125599_126190_-	hypothetical protein	NA	NA	NA	NA
AXO02767.1\|126202_126730_-	hypothetical protein	NA	NA	NA	NA
AXO02768.1\|126760_127171_-	XRE family transcriptional regulator	Q6QID2	Burkholderia_phage	8.9e-14	39.4
AXO02769.1\|127639_127876_+	DNA-binding protein	NA	NA	NA	NA
AXO02770.1\|127955_128141_+	hypothetical protein	NA	NA	NA	NA
AXO02771.1\|128153_128468_+	IclR family transcriptional regulator	Q5ZR02	Pseudomonas_phage	5.8e-13	41.1
AXO02772.1\|128478_129423_+	hypothetical protein	J9SND0	Pseudomonas_phage	2.3e-28	31.5
AXO02773.1\|129434_131204_+\|transposase	transposase	Q6QIE0	Burkholderia_phage	1.8e-148	46.5
AXO02774.1\|131215_132394_+\|transposase	transposase	Q6QIE1	Burkholderia_phage	4.6e-111	54.8
AXO02775.1\|132396_132720_+	hypothetical protein	NA	NA	NA	NA
AXO02776.1\|132729_132951_+	hypothetical protein	NA	NA	NA	NA
AXO02777.1\|132925_133180_+	hypothetical protein	NA	NA	NA	NA
AXO02778.1\|133199_133820_+	DUF3164 family protein	A0A0M3LQ92	Mannheimia_phage	1.2e-67	60.2
AXO02779.1\|133989_134217_+	hypothetical protein	NA	NA	NA	NA
AXO02780.1\|134213_134759_+	hypothetical protein	NA	NA	NA	NA
AXO02781.1\|134768_135329_+	hypothetical protein	A0A0M3LP85	Mannheimia_phage	8.2e-18	29.7

DBSCAN-SWA_2

309510 : 318868

Sinorhizobium_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO02916.1\|309510_310785_+	multifunctional CCA addition/repair protein	A0A0F6YPT7	Sinorhizobium_phage	1.8e-92	49.5
AXO02917.1\|310825_311443_+	lipoprotein localization protein LolB	NA	NA	NA	NA
AXO02918.1\|311442_312330_+	4-diphosphocytidyl-2C-methyl-D-erythritol kinase	NA	NA	NA	NA
AXO02919.1\|312399_313347_+	ribose-phosphate pyrophosphokinase	A0A2K9L2G2	Tupanvirus	1.5e-43	39.0
AXO02920.1\|313422_314976_-	murein DD-endopeptidase MepM	A0A2K9VGT1	Pontimonas_phage	8.4e-20	49.6
AXO02921.1\|315210_316002_+	zinc ABC transporter ATP-binding protein ZnuC	W6JKT0	Anomala_cuprea_entomopoxvirus	4.4e-17	29.7
AXO02922.1\|316010_316796_+	zinc ABC transporter permease subunit ZnuB	NA	NA	NA	NA
AXO02923.1\|316872_317853_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.3e-15	26.4
AXO02924.1\|317869_318868_-	dipeptide ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.3e-15	29.4

DBSCAN-SWA_3

666118 : 675556

Lactococcus_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO03223.1\|666118_668521_+	ribonuclease R	Q0GXV6	Lactococcus_phage	5.2e-69	33.2
AXO03224.1\|668521_669259_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
AXO03225.1\|669343_669904_-	superoxide dismutase	Q9MC02	Salmonella_phage	1.6e-50	61.8
AXO03226.1\|669974_672806_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	57.2
AXO03227.1\|672977_673478_+	single-stranded DNA-binding protein	I3PUY5	Vibrio_phage	4.0e-40	55.6
AXO03228.1\|673660_674125_+\|transposase	IS200/IS605 family transposase	A0A0A8WIU6	Clostridium_phage	2.3e-13	36.1
AXO03229.1\|674701_675556_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	5.8e-31	40.3

DBSCAN-SWA_4

855415 : 951240

Escherichia_phage(17.95%)

plate,terminase,tRNA,transposase,head,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO03385.1\|855415_856798_+\|tRNA	L-seryl-tRNA(Sec) selenium transferase	NA	NA	NA	NA
AXO03386.1\|856833_857766_-	nucleoside hydrolase	NA	NA	NA	NA
AXO03387.1\|857986_859861_+	selenocysteine-specific translation elongation factor	A0A2K9KZ60	Tupanvirus	7.5e-15	26.2
AXO03388.1\|859911_860460_-	ferredoxin-type protein NapF	NA	NA	NA	NA
AXO04832.1\|860477_861083_-	Tat proofreading chaperone DmsD	A0A077SLS7	Escherichia_phage	3.1e-23	36.7
AXO03389.1\|861171_862020_-	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
AXO03390.1\|862021_862642_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	1.4e-71	58.8
AXO03391.1\|863581_864292_-	helix-turn-helix transcriptional regulator	F6MII3	Haemophilus_phage	6.4e-52	48.4
AXO03392.1\|864467_864734_+	transcriptional regulator	F6MII4	Haemophilus_phage	1.2e-19	63.4
AXO03393.1\|864778_866764_+	DDE endonuclease	M4M9R2	Vibrio_phage	7.1e-157	45.1
AXO03394.1\|866774_867692_+	winged helix-turn-helix transcriptional regulator	M4M9P4	Vibrio_phage	1.5e-61	43.5
AXO03395.1\|867694_867991_+	hypothetical protein	NA	NA	NA	NA
AXO03396.1\|868004_868232_+	hypothetical protein	NA	NA	NA	NA
AXO03397.1\|868246_868768_+	host-nuclease inhibitor protein Gam	C9DGL8	Escherichia_phage	1.0e-46	54.4
AXO03398.1\|868853_869042_+	ANR family transcriptional regulator	NA	NA	NA	NA
AXO03399.1\|869249_870164_+	hypothetical protein	NA	NA	NA	NA
AXO03400.1\|870233_870734_+	regulatory protein GemA	NA	NA	NA	NA
AXO03401.1\|870730_871273_+	hypothetical protein	A0A0M3LPP6	Mannheimia_phage	2.4e-38	43.7
AXO03402.1\|871272_871635_+	transcriptional regulator	Q6QIE8	Burkholderia_phage	2.9e-24	44.2
AXO03403.1\|871753_872176_+	hypothetical protein	NA	NA	NA	NA
AXO03404.1\|872300_872837_+	N-acetylmuramoyl-L-alanine amidase	F6MIJ9	Haemophilus_phage	1.3e-73	69.7
AXO03405.1\|872847_873075_+	DUF2644 domain-containing protein	F6MIK0	Haemophilus_phage	6.0e-20	72.4
AXO03406.1\|873071_873332_+	DUF2681 domain-containing protein	NA	NA	NA	NA
AXO03407.1\|873449_873779_+	DUF2730 family protein	NA	NA	NA	NA
AXO03408.1\|873775_874078_+	hypothetical protein	A0A0C4UR00	Shigella_phage	2.2e-25	61.5
AXO03409.1\|874100_874673_+	DUF3486 family protein	M4MCR3	Vibrio_phage	1.7e-34	44.0
AXO03410.1\|874659_875967_+\|terminase	terminase	A0A2P9JZI8	Alteromonadaceae_phage	6.5e-151	65.7
AXO03411.1\|875968_877384_+	DUF935 family protein	Q6QIC0	Burkholderia_phage	2.0e-113	45.8
AXO03412.1\|877384_878656_+\|head	phage head morphogenesis protein	J9STS2	Pseudomonas_phage	2.5e-54	49.1
AXO03413.1\|878784_879249_+	phage virion morphogenesis protein	Q6QIB8	Burkholderia_phage	6.8e-10	38.8
AXO03414.1\|879499_880603_+	peptidase	A4JWJ9	Burkholderia_virus	4.6e-73	42.0
AXO03415.1\|880621_881548_+	hypothetical protein	A4JWK0	Burkholderia_virus	1.0e-73	47.9
AXO03416.1\|881613_881931_+	hypothetical protein	NA	NA	NA	NA
AXO03417.1\|881930_882365_+	DUF1320 domain-containing protein	A4JWK2	Burkholderia_virus	4.0e-20	37.8
AXO03418.1\|882376_882874_+	hypothetical protein	NA	NA	NA	NA
AXO03419.1\|882883_884269_+\|tail	phage tail protein	A4JWK5	Burkholderia_virus	2.0e-97	44.3
AXO03420.1\|884279_884798_+\|tail	phage major tail tube protein	A4JWK6	Burkholderia_virus	3.9e-38	45.0
AXO03421.1\|884890_885160_+\|tail	phage tail assembly protein	NA	NA	NA	NA
AXO03422.1\|885180_885315_+\|tail	GpE family phage tail protein	NA	NA	NA	NA
AXO03423.1\|885330_885564_-	hypothetical protein	NA	NA	NA	NA
AXO03424.1\|885598_887947_+\|tail	phage tail tape measure protein	K4ICR4	Acidithiobacillus_phage	1.1e-71	38.8
AXO03425.1\|887946_888879_+	hypothetical protein	NA	NA	NA	NA
AXO03426.1\|888859_889090_+	hypothetical protein	Q6QIA3	Burkholderia_phage	7.2e-13	47.8
AXO03427.1\|889082_890147_+	hypothetical protein	NA	NA	NA	NA
AXO03428.1\|890133_890703_+\|plate	phage baseplate assembly protein V	NA	NA	NA	NA
AXO03429.1\|890757_891123_+\|plate	phage baseplate protein	NA	NA	NA	NA
AXO03430.1\|891122_892229_+\|plate	baseplate J/gp47 family protein	A4JWL6	Burkholderia_virus	3.6e-57	36.4
AXO03431.1\|892221_892791_+\|tail	phage tail protein	A4JWL7	Burkholderia_virus	4.5e-40	44.8
AXO03432.1\|895338_895518_+	hypothetical protein	NA	NA	NA	NA
AXO03433.1\|897714_898434_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	2.0e-16	34.2
AXO03434.1\|898577_900071_-	PTS glucose transporter subunit IIB	NA	NA	NA	NA
AXO03435.1\|900290_901154_+	4-hydroxybenzoate octaprenyltransferase	NA	NA	NA	NA
AXO03436.1\|901265_901796_+	HslU--HslV peptidase proteolytic subunit	NA	NA	NA	NA
AXO03437.1\|901811_903143_+	HslU--HslV peptidase ATPase subunit	A0A2H5BJT2	Erwinia_phage	4.6e-43	29.1
AXO03438.1\|903223_904174_-	type I pantothenate kinase	A0A1B1ISL9	uncultured_Mediterranean_phage	3.9e-28	32.7
AXO03439.1\|904891_906076_+	elongation factor Tu	A0A2K9L516	Tupanvirus	8.3e-12	25.3
AXO03440.1\|906198_907539_-	phospholipase	NA	NA	NA	NA
AXO03441.1\|907603_909070_-	GntP family permease	NA	NA	NA	NA
AXO03442.1\|909081_910029_-	NAD-dependent epimerase/dehydratase family protein	A0A0N7KVW3	Yellowstone_lake_phycodnavirus	3.4e-08	26.0
AXO03443.1\|910167_911967_-	alpha/beta hydrolase	NA	NA	NA	NA
AXO03444.1\|911968_912643_-	cyclase family protein	NA	NA	NA	NA
AXO03445.1\|912658_913441_-	hydroxypyruvate isomerase	NA	NA	NA	NA
AXO03446.1\|913442_914075_-	aldolase	A0A077SK32	Escherichia_phage	2.2e-64	60.0
AXO03447.1\|914071_915313_-	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	3.2e-115	53.5
AXO03448.1\|915315_916221_-	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	8.9e-115	72.9
AXO03449.1\|916435_917197_+	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	7.9e-64	52.4
AXO03450.1\|917254_918715_-	aminoacyl-histidine dipeptidase	NA	NA	NA	NA
AXO03451.1\|918873_919335_+	xanthine phosphoribosyltransferase	NA	NA	NA	NA
AXO03452.1\|919409_920594_-	mannonate dehydratase	NA	NA	NA	NA
AXO03453.1\|921051_921798_-	GntR family transcriptional regulator	NA	NA	NA	NA
AXO03454.1\|923079_923568_+	TRAP transporter small permease	NA	NA	NA	NA
AXO03455.1\|923582_924893_+	TRAP transporter large permease	NA	NA	NA	NA
AXO03456.1\|924942_925788_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AXO03457.1\|925813_927217_+	glucuronate isomerase	NA	NA	NA	NA
AXO03458.1\|927226_928168_+	sugar kinase	NA	NA	NA	NA
AXO03459.1\|928186_928825_+	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase	NA	NA	NA	NA
AXO03460.1\|928886_930602_-\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
AXO03461.1\|930843_932313_-	xylulokinase	NA	NA	NA	NA
AXO03462.1\|932375_933698_-	xylose isomerase	NA	NA	NA	NA
AXO03463.1\|933912_935103_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
AXO03464.1\|935095_936499_+	Na+/H+ antiporter NhaC	NA	NA	NA	NA
AXO03465.1\|936755_937754_+	D-xylose ABC transporter substrate-binding protein	NA	NA	NA	NA
AXO03466.1\|937815_939330_+	D-xylose ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.6e-21	34.7
AXO03467.1\|939333_940461_+	sugar ABC transporter permease	NA	NA	NA	NA
AXO03468.1\|940587_941757_+	xylose operon transcription regulator XylR	NA	NA	NA	NA
AXO03469.1\|941765_942755_-	carbohydrate kinase family protein	NA	NA	NA	NA
AXO03470.1\|942741_943626_-	ketose 1,6-bisphosphate aldolase	NA	NA	NA	NA
AXO03471.1\|943627_944311_-	D-lyxose/D-mannose family sugar isomerase	NA	NA	NA	NA
AXO03472.1\|944364_945276_-	fructokinase	NA	NA	NA	NA
AXO03473.1\|945376_946096_+	DNA-binding response regulator	NA	NA	NA	NA
AXO03474.1\|946158_947088_-	transcriptional regulator	NA	NA	NA	NA
AXO03475.1\|947115_948087_-	ribose ABC transporter permease	NA	NA	NA	NA
AXO03476.1\|948125_949640_-	sugar ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	5.1e-14	27.2
AXO03477.1\|949933_950647_+	pirin family protein	NA	NA	NA	NA
AXO03478.1\|950775_951240_-\|transposase	IS200/IS605 family transposase	A0A0A8WIU6	Clostridium_phage	2.3e-13	36.1

DBSCAN-SWA_5

1592226 : 1635936

Mannheimia_phage(48.65%)

coat,integrase,terminase,head,tail

attL 1592077:1592122|attR 1646235:1646280

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1592077:1592122	attL	NA	NA	NA	NA
AXO04072.1\|1592226_1593399_-\|integrase	site-specific integrase	A0A059VF45	Pseudomonas_phage	2.0e-111	53.1
AXO04073.1\|1593774_1594230_-	pyruvate kinase	A0A0M3LPG0	Mannheimia_phage	4.6e-27	47.1
AXO04074.1\|1594274_1594628_-	hypothetical protein	NA	NA	NA	NA
AXO04075.1\|1594636_1595134_-	DUF551 domain-containing protein	NA	NA	NA	NA
AXO04076.1\|1595268_1595868_-	HD family hydrolase	A0A218KC93	Bacillus_phage	4.6e-19	37.6
AXO04077.1\|1595918_1596707_-	DUF2303 family protein	C5IHK3	Burkholderia_virus	4.2e-20	29.6
AXO04078.1\|1596778_1597132_-	hypothetical protein	I6XKT1	Burkholderia_virus	1.7e-05	31.8
AXO04079.1\|1597204_1597657_-	single-stranded DNA-binding protein	F8TUL2	EBPR_podovirus	1.4e-36	52.9
AXO04080.1\|1597656_1598196_-	HNH endonuclease	U5XJH2	Phormidium_phage	4.8e-07	44.1
AXO04849.1\|1598195_1598855_-	translocation protein TolB precursor	A0A0M3LP90	Mannheimia_phage	1.2e-95	74.9
AXO04081.1\|1598841_1599795_-	recombinase	A0A0M3LNU3	Mannheimia_phage	1.2e-122	72.8
AXO04082.1\|1599796_1600084_-	hypothetical protein	NA	NA	NA	NA
AXO04083.1\|1600096_1600333_-	hypothetical protein	NA	NA	NA	NA
AXO04084.1\|1600304_1600604_-	hypothetical protein	NA	NA	NA	NA
AXO04085.1\|1600670_1600982_+	hypothetical protein	NA	NA	NA	NA
AXO04850.1\|1601043_1601700_-	KilA-N domain-containing protein	K7PH30	Enterobacteria_phage	2.7e-20	46.6
AXO04086.1\|1602623_1603421_-	hypothetical protein	NA	NA	NA	NA
AXO04087.1\|1603639_1604020_-	hypothetical protein	NA	NA	NA	NA
AXO04088.1\|1604197_1604470_+	CRISPR-associated protein Cas2	A0A0M3LS55	Mannheimia_phage	5.5e-36	78.9
AXO04089.1\|1604462_1604651_-	hypothetical protein	NA	NA	NA	NA
AXO04090.1\|1604947_1605142_+	hypothetical protein	NA	NA	NA	NA
AXO04091.1\|1605305_1605536_-	hypothetical protein	NA	NA	NA	NA
AXO04092.1\|1606044_1606569_-	DUF2730 family protein	A0A0M3LP99	Mannheimia_phage	1.3e-22	60.4
AXO04093.1\|1606540_1606936_-	hypothetical protein	A0A0M3LQX0	Mannheimia_phage	2.2e-57	77.8
AXO04094.1\|1606955_1607645_-	helix-turn-helix transcriptional regulator	Q7Y5W5	Haemophilus_phage	9.6e-69	56.2
AXO04095.1\|1607766_1607967_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AXO04096.1\|1608015_1608468_+	hypothetical protein	NA	NA	NA	NA
AXO04097.1\|1608519_1609203_+	hypothetical protein	D0UIL6	Aggregatibacter_phage	9.5e-77	67.9
AXO04098.1\|1609199_1609415_+	hypothetical protein	NA	NA	NA	NA
AXO04099.1\|1609411_1610170_+	helix-turn-helix domain-containing protein	D0UIL5	Aggregatibacter_phage	1.5e-46	85.3
AXO04100.1\|1610166_1611522_+	DNA helicase	A0A0M3LQC0	Mannheimia_phage	5.2e-127	52.2
AXO04101.1\|1611524_1611950_+	recombination protein NinB	Q7Y5V7	Haemophilus_phage	5.6e-43	59.3
AXO04102.1\|1612023_1612239_+	hypothetical protein	NA	NA	NA	NA
AXO04103.1\|1612231_1612834_+	recombinase NinG	H6WRY9	Salmonella_phage	4.8e-32	38.2
AXO04104.1\|1612835_1613297_+	antitermination protein	NA	NA	NA	NA
AXO04105.1\|1613426_1613984_-	hypothetical protein	NA	NA	NA	NA
AXO04106.1\|1614100_1614361_+	hypothetical protein	NA	NA	NA	NA
AXO04107.1\|1614357_1614888_+	lysozyme	A0A0M3LPQ1	Mannheimia_phage	2.0e-45	51.4
AXO04851.1\|1614860_1615184_+	DUF2570 domain-containing protein	NA	NA	NA	NA
AXO04108.1\|1615089_1615371_+	hypothetical protein	NA	NA	NA	NA
AXO04852.1\|1615607_1615943_+	DUF2829 domain-containing protein	F8WPN8	Bacillus_phage	1.9e-14	45.3
AXO04109.1\|1616230_1616431_+	hypothetical protein	NA	NA	NA	NA
AXO04110.1\|1616554_1616791_-	XRE family transcriptional regulator	NA	NA	NA	NA
AXO04111.1\|1616787_1617084_-	hypothetical protein	S5M7P0	Sinorhizobium_phage	1.9e-13	43.0
AXO04112.1\|1617216_1617918_+	phosphoadenosine phosphosulfate reductase	NA	NA	NA	NA
AXO04113.1\|1617904_1618333_+	hypothetical protein	NA	NA	NA	NA
AXO04114.1\|1618648_1619239_+	hypothetical protein	A0A2H4J1J5	uncultured_Caudovirales_phage	3.7e-21	39.5
AXO04115.1\|1619241_1620513_+\|terminase	terminase	A0A1B1P9C9	Acinetobacter_phage	4.3e-147	61.4
AXO04116.1\|1620522_1621926_+	DUF4055 domain-containing protein	A0A0M3LQA1	Mannheimia_phage	6.8e-154	59.8
AXO04853.1\|1621915_1623517_+\|head	phage head morphogenesis protein	A0A0M3LQ07	Mannheimia_phage	4.7e-151	52.1
AXO04117.1\|1623519_1623738_+	hypothetical protein	NA	NA	NA	NA
AXO04118.1\|1623712_1624147_+	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	D0UIJ3	Aggregatibacter_phage	7.7e-40	60.1
AXO04119.1\|1624183_1624582_+	hypothetical protein	NA	NA	NA	NA
AXO04120.1\|1624757_1625543_+	hypothetical protein	A0A1V0DY60	Dinoroseobacter_phage	1.1e-25	36.5
AXO04121.1\|1625560_1626718_+\|coat	P22 coat - protein 5 family protein	G8C7P7	Escherichia_phage	1.3e-81	43.6
AXO04122.1\|1626774_1627011_+	hypothetical protein	NA	NA	NA	NA
AXO04123.1\|1627027_1627495_+	hypothetical protein	A0A0M3LSP7	Mannheimia_phage	1.4e-34	55.7
AXO04124.1\|1627496_1627871_+	hypothetical protein	NA	NA	NA	NA
AXO04854.1\|1627872_1628274_+	HK97 gp10 family phage protein	A0A0M3LPJ5	Mannheimia_phage	2.1e-39	61.4
AXO04125.1\|1628273_1628666_+	hypothetical protein	A0A0M3LQB6	Mannheimia_phage	5.5e-29	46.2
AXO04126.1\|1628678_1629695_+	hypothetical protein	A0A0M3LQ19	Mannheimia_phage	1.1e-129	69.3
AXO04127.1\|1629767_1630184_+	hypothetical protein	NA	NA	NA	NA
AXO04128.1\|1630183_1630513_+	hypothetical protein	A0A0M3LQT0	Mannheimia_phage	1.8e-25	54.8
AXO04129.1\|1630552_1630882_+\|tail	phage tail protein	A0A0M3LQW6	Mannheimia_phage	1.9e-27	50.9
AXO04130.1\|1630953_1631649_+	hypothetical protein	NA	NA	NA	NA
AXO04131.1\|1634483_1635188_+\|tail	phage minor tail protein L	A0A0M3LPR8	Mannheimia_phage	1.0e-81	64.4
AXO04855.1\|1635192_1635936_+\|tail	phage tail protein	A0A0M3LQI5	Mannheimia_phage	7.9e-85	60.8
1646235:1646280	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1659156 : 1742875

Shigella_phage(23.81%)

plate,tRNA,transposase,head,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXO04148.1\|1659156_1660365_+\|transposase	IS4-like element ISVsa5 family transposase	Q9E8P4	Bluetongue_virus	3.0e-235	100.0
AXO04149.1\|1660790_1662209_+	aspartate ammonia-lyase	NA	NA	NA	NA
AXO04150.1\|1662344_1664414_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
AXO04151.1\|1664443_1664824_-	hypothetical protein	NA	NA	NA	NA
AXO04152.1\|1664954_1665578_-	glutathione S-transferase	NA	NA	NA	NA
AXO04153.1\|1665595_1665859_-	hypothetical protein	NA	NA	NA	NA
AXO04154.1\|1665889_1666795_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
AXO04155.1\|1667073_1668327_+	DUF2254 domain-containing protein	NA	NA	NA	NA
AXO04156.1\|1668437_1669295_+	1,4-dihydroxy-2-naphthoyl-CoA synthase	NA	NA	NA	NA
AXO04157.1\|1669547_1670561_+	o-succinylbenzoate synthase	NA	NA	NA	NA
AXO04158.1\|1670631_1671078_+	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
AXO04159.1\|1671232_1671694_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
AXO04160.1\|1671795_1673142_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
AXO04161.1\|1673224_1673476_+	DUF997 family protein	NA	NA	NA	NA
AXO04162.1\|1673465_1674899_+	sodium/pantothenate symporter	NA	NA	NA	NA
AXO04163.1\|1675041_1675923_+	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
AXO04164.1\|1676199_1677204_+\|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA
AXO04165.1\|1677184_1677484_+	DNA-binding transcriptional regulator Fis	NA	NA	NA	NA
AXO04166.1\|1677708_1681602_+	phosphoribosylformylglycinamidine synthase	A9YX36	Burkholderia_phage	1.5e-113	53.2
AXO04167.1\|1682035_1682608_-	hypothetical protein	NA	NA	NA	NA
AXO04168.1\|1682621_1683860_-	DUF262 domain-containing protein	A0A0R6PKN1	Moraxella_phage	1.0e-12	25.6
AXO04169.1\|1684877_1685903_+	hypothetical protein	NA	NA	NA	NA
AXO04170.1\|1686367_1688797_+	TonB-dependent receptor	NA	NA	NA	NA
AXO04171.1\|1688942_1689680_-	ABC transporter ATP-binding protein	M1HP82	Acanthocystis_turfacea_Chlorella_virus	1.9e-14	32.5
AXO04172.1\|1689691_1690636_-	iron ABC transporter permease	NA	NA	NA	NA
AXO04173.1\|1690648_1691437_-	hemin ABC transporter substrate-binding protein	NA	NA	NA	NA
AXO04174.1\|1691744_1692299_-	hypothetical protein	NA	NA	NA	NA
AXO04175.1\|1692779_1693859_+	endonuclease	NA	NA	NA	NA
AXO04176.1\|1693948_1695604_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	7.4e-83	34.9
AXO04177.1\|1695821_1696376_-	hypothetical protein	NA	NA	NA	NA
AXO04178.1\|1696523_1698281_-	ABC transporter ATP-binding protein/permease	NA	NA	NA	NA
AXO04179.1\|1698465_1700127_+	putative transporter	NA	NA	NA	NA
AXO04180.1\|1700174_1700465_-	DUF406 family protein	NA	NA	NA	NA
AXO04181.1\|1700709_1702020_+	porin	NA	NA	NA	NA
AXO04182.1\|1702082_1702625_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	4.8e-23	45.7
AXO04183.1\|1702634_1703303_+	DNA mismatch repair protein MutH	NA	NA	NA	NA
AXO04184.1\|1703368_1704097_+	TerC family protein	A0A0R6PEZ3	Moraxella_phage	4.9e-31	38.1
AXO04185.1\|1704377_1704638_+	hypothetical protein	F6MIM3	Haemophilus_phage	6.4e-42	100.0
AXO04856.1\|1704678_1705464_-	hypothetical protein	F6MIM2	Haemophilus_phage	5.3e-148	95.4
AXO04186.1\|1705602_1705887_-	DNA helicase UvrD	Q776W9	Haemophilus_phage	2.8e-22	62.5
AXO04187.1\|1705865_1706414_-	hypothetical protein	NA	NA	NA	NA
AXO04188.1\|1706416_1708636_-	hypothetical protein	A0A1Y0SVL0	Pasteurella_phage	7.3e-86	33.4
AXO04857.1\|1708638_1709196_-	DUF2313 domain-containing protein	A0A2I7S9L6	Vibrio_phage	1.9e-22	34.6
AXO04189.1\|1709228_1710296_-\|plate	baseplate J/gp47 family protein	A0A0C4UQU9	Shigella_phage	9.3e-71	43.1
AXO04190.1\|1710295_1710706_-	hypothetical protein	A0A0C4UR04	Shigella_phage	3.5e-18	38.7
AXO04191.1\|1710716_1711265_-\|plate	phage baseplate assembly protein V	A0A0C4UQZ3	Shigella_phage	2.2e-31	47.0
AXO04192.1\|1711296_1711776_-\|tail	phage tail protein	M4M9L5	Vibrio_phage	1.2e-14	39.0
AXO04193.1\|1711779_1712547_-\|tail	phage tail protein	A0A0C4UQS1	Shigella_phage	4.1e-44	37.4
AXO04194.1\|1712546_1713911_-	DNA circularization protein	A0A0C4UR32	Shigella_phage	2.3e-34	27.5
AXO04195.1\|1713920_1715813_-	tape measure domain-containing protein	A0A2I7S9D9	Vibrio_phage	3.0e-56	35.2
AXO04196.1\|1715902_1716286_-	hypothetical protein	C9DGP9	Escherichia_phage	6.4e-22	52.1
AXO04197.1\|1716289_1716643_-\|tail	phage tail protein	A0A2P1A4D6	Alteromonadaceae_phage	1.7e-08	32.7
AXO04198.1\|1716653_1718117_-\|tail	phage tail protein	A0A0C4UQS0	Shigella_phage	4.0e-125	50.6
AXO04199.1\|1718116_1718308_-	DUF2635 domain-containing protein	NA	NA	NA	NA
AXO04200.1\|1718319_1718874_-	DUF1834 family protein	NA	NA	NA	NA
AXO04201.1\|1718870_1719293_-	DUF1320 domain-containing protein	NA	NA	NA	NA
AXO04202.1\|1719289_1719694_-	hypothetical protein	NA	NA	NA	NA
AXO04203.1\|1719782_1720706_-\|head	head protein	A0A0C4UQR9	Shigella_phage	7.5e-93	55.1
AXO04204.1\|1720705_1721770_-	hypothetical protein	A0A0C4UQU6	Shigella_phage	2.1e-70	48.0
AXO04205.1\|1721998_1722433_-	phage virion morphogenesis protein	NA	NA	NA	NA
AXO04206.1\|1722497_1722728_+	hypothetical protein	NA	NA	NA	NA
AXO04207.1\|1723007_1724342_-\|head	phage head morphogenesis protein	C9DGN7	Escherichia_phage	4.3e-89	42.1
AXO04858.1\|1724328_1725888_-	DUF935 domain-containing protein	A0A0C4UQR8	Shigella_phage	1.2e-146	52.8
AXO04859.1\|1725890_1727405_-	hypothetical protein	A0A2I7S9C5	Vibrio_phage	1.2e-156	61.4
AXO04208.1\|1727461_1728031_-	DUF3486 family protein	A0A2I7S9D1	Vibrio_phage	1.7e-42	45.9
AXO04209.1\|1728064_1728358_-	hypothetical protein	A0A2I7S9D8	Vibrio_phage	1.4e-24	65.6
AXO04210.1\|1728354_1728684_-	DUF2730 family protein	NA	NA	NA	NA
AXO04211.1\|1728680_1728908_-	TraR/DksA family transcriptional regulator	NA	NA	NA	NA
AXO04212.1\|1728900_1729119_-	hypothetical protein	F6MIK2	Haemophilus_phage	2.5e-07	61.2
AXO04213.1\|1729036_1729309_-	DUF2681 domain-containing protein	NA	NA	NA	NA
AXO04214.1\|1729311_1729530_-	DUF2644 domain-containing protein	F6MIK0	Haemophilus_phage	9.2e-26	88.4
AXO04215.1\|1729532_1730081_-	N-acetylmuramoyl-L-alanine amidase	F6MIJ9	Haemophilus_phage	3.3e-72	70.6
AXO04216.1\|1730160_1730676_-	hypothetical protein	NA	NA	NA	NA
AXO04217.1\|1730684_1731119_-	transcriptional regulator	A0A0C4UQZ9	Shigella_phage	4.2e-22	43.3
AXO04218.1\|1731322_1731877_-	hypothetical protein	A0A0M3LPP6	Mannheimia_phage	1.3e-44	53.0
AXO04219.1\|1731863_1732412_-	DUF1018 domain-containing protein	NA	NA	NA	NA
AXO04220.1\|1732548_1732965_-	hypothetical protein	NA	NA	NA	NA
AXO04221.1\|1732966_1733152_-	hypothetical protein	F6MIJ2	Haemophilus_phage	6.4e-20	96.4
AXO04222.1\|1733151_1733370_-	ANR family transcriptional regulator	NA	NA	NA	NA
AXO04223.1\|1733445_1733742_-	hypothetical protein	NA	NA	NA	NA
AXO04224.1\|1733738_1734263_-	host-nuclease inhibitor protein Gam	F6MIJ0	Haemophilus_phage	2.3e-83	92.5
AXO04225.1\|1734287_1734605_-	hypothetical protein	A0A0M3LQH1	Mannheimia_phage	1.5e-13	45.2
AXO04226.1\|1735559_1736066_+	hypothetical protein	NA	NA	NA	NA
AXO04227.1\|1736166_1738158_-\|transposase	transposase	C9DGL1	Escherichia_phage	9.3e-149	44.7
AXO04228.1\|1738169_1738382_-	transcriptional regulator	A0A0M3LPY8	Mannheimia_phage	1.9e-20	70.6
AXO04229.1\|1738595_1739135_+	DNA-binding protein	A0A0M3LP76	Mannheimia_phage	7.4e-16	69.1
AXO04230.1\|1739492_1739957_+\|transposase	IS200/IS605 family transposase	A0A0A8WIU6	Clostridium_phage	2.3e-13	36.1
AXO04231.1\|1740082_1742875_-	DNA polymerase I	A0A142F1Q9	Bacillus_phage	5.4e-78	33.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP031554

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection