CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP022723	Bifidobacterium bifidum strain S6 chromosome, complete genome	0 crisprs	DEDDh,WYL,cas3,cas9,cas1,cas2,csn2	0	0	3	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

52150 : 102686

uncultured_Mediterranean_phage(25.0%)

transposase,protease,integrase,tRNA

attL 47676:47693|attR 106895:106912

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
47676:47693	attL	NA	NA	NA	NA
AXM90777.1\|52150_53236_+\|integrase	site-specific integrase	A0A0E3XBN7	Gordonia_phage	8.9e-61	39.0
AXM90778.1\|53252_53816_-	hypothetical protein	NA	NA	NA	NA
AXM90779.1\|53808_54978_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
AXM90780.1\|55393_56332_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
AXM90781.1\|56503_57955_-	glutamate synthase	NA	NA	NA	NA
AXM90782.1\|58125_60327_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	6.7e-39	28.5
AXM90783.1\|60705_62619_-	peptidase	A0A1B1IT49	uncultured_Mediterranean_phage	8.4e-14	25.8
AXM90784.1\|62987_64289_+\|tRNA	tRNA-guanine(34) transglycosylase	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.8e-53	32.4
AXM90785.1\|64655_64916_+	hypothetical protein	NA	NA	NA	NA
AXM92317.1\|64922_65420_-	N-acetyltransferase	NA	NA	NA	NA
AXM90786.1\|65416_66235_-	alpha/beta hydrolase	NA	NA	NA	NA
AXM90787.1\|66356_66689_-	hypothetical protein	NA	NA	NA	NA
AXM90788.1\|66731_66968_-	hypothetical protein	NA	NA	NA	NA
AXM90789.1\|67001_67439_+	DivIVA domain-containing protein	NA	NA	NA	NA
AXM90790.1\|67589_68105_+	(deoxy)nucleoside triphosphate pyrophosphohydrolase	NA	NA	NA	NA
AXM90791.1\|68101_71287_+	DUF3427 domain-containing protein	U3PFS7	Lactobacillus_phage	2.9e-19	26.0
AXM90792.1\|71306_71513_+	hypothetical protein	NA	NA	NA	NA
AXM90793.1\|71636_72137_+	hypothetical protein	NA	NA	NA	NA
AXM92318.1\|72141_73146_-	peptide-methionine (R)-S-oxide reductase	NA	NA	NA	NA
AXM90794.1\|73247_73748_-	hypothetical protein	NA	NA	NA	NA
AXM90795.1\|73826_74582_-	DUF1109 domain-containing protein	NA	NA	NA	NA
AXM92319.1\|74845_75796_-	EamA family transporter	NA	NA	NA	NA
AXM90796.1\|75855_76911_-	alpha/beta hydrolase	NA	NA	NA	NA
AXM90797.1\|77064_79392_-	hypothetical protein	NA	NA	NA	NA
AXM90798.1\|79388_82214_-	ABC transporter	NA	NA	NA	NA
AXM92320.1\|82438_84970_-	peptidase	NA	NA	NA	NA
AXM90799.1\|85209_85911_+	DUF2662 domain-containing protein	NA	NA	NA	NA
AXM90800.1\|85938_86481_+	FHA domain-containing protein	NA	NA	NA	NA
AXM90801.1\|86487_88137_+	serine/threonine-protein phosphatase	NA	NA	NA	NA
AXM90802.1\|88133_89612_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
AXM90803.1\|89608_91075_+	penicillin-binding protein	NA	NA	NA	NA
AXM90804.1\|92056_94114_+	serine/threonine protein kinase	Q8JE84	Murine_leukemia_virus	2.0e-16	31.8
AXM90805.1\|94339_94984_-	glutamine amidotransferase	A0A0P0IKJ1	Acinetobacter_phage	1.3e-35	40.7
AXM90806.1\|95079_96309_-	class E sortase	NA	NA	NA	NA
AXM90807.1\|96305_97094_-	DUF881 domain-containing protein	NA	NA	NA	NA
AXM90808.1\|97171_97612_+	septation inhibitor protein	NA	NA	NA	NA
AXM90809.1\|97737_99066_-	SAM-dependent methyltransferase	NA	NA	NA	NA
AXM90810.1\|99498_99600_-\|integrase	integrase	NA	NA	NA	NA
AXM90811.1\|100019_100805_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
AXM90812.1\|100991_101213_+	hypothetical protein	NA	NA	NA	NA
AXM92321.1\|101319_102174_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.6e-44	38.1
AXM90813.1\|102125_102686_-\|transposase	IS3 family transposase	NA	NA	NA	NA
106895:106912	attR	NA	NA	NA	NA

DBSCAN-SWA_2

422621 : 463523

Gordonia_phage(25.0%)

holin,tRNA,transposase,capsid,tail,integrase,portal

attL 427862:427877|attR 459431:459446

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXM91006.1\|422621_422921_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit C	NA	NA	NA	NA
AXM91007.1\|422923_424462_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit A	NA	NA	NA	NA
AXM91008.1\|424486_425986_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase GatCAB subunit B	NA	NA	NA	NA
AXM91009.1\|426201_427245_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AXM91010.1\|427241_427556_+	DUF2469 domain-containing protein	NA	NA	NA	NA
AXM91011.1\|427795_429409_+	hypothetical protein	NA	NA	NA	NA
427862:427877	attL	NA	NA	NA	NA
AXM91012.1\|429613_431674_+	transcription termination factor Rho	NA	NA	NA	NA
AXM91013.1\|431771_433001_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
AXM91014.1\|433170_433713_+	AsnC family transcriptional regulator	NA	NA	NA	NA
AXM91015.1\|433825_434254_+	chorismate mutase	NA	NA	NA	NA
AXM92353.1\|434375_436556_+	hypothetical protein	NA	NA	NA	NA
AXM91016.1\|436666_439408_-\|tRNA	valine--tRNA ligase	A0A2K9KZB8	Tupanvirus	1.8e-163	38.6
AXM91017.1\|439490_441047_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
AXM92354.1\|441130_441757_-	endonuclease III	NA	NA	NA	NA
AXM91018.1\|441805_442567_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	6.3e-13	33.1
AXM91019.1\|442713_443472_+	hypothetical protein	NA	NA	NA	NA
AXM91020.1\|443844_444432_-	hypothetical protein	NA	NA	NA	NA
AXM91021.1\|444964_445459_-	inorganic pyrophosphatase	NA	NA	NA	NA
AXM91022.1\|445625_447941_-	DUF3416 domain-containing protein	NA	NA	NA	NA
AXM92355.1\|448218_450438_+	peptidase	NA	NA	NA	NA
AXM91023.1\|450588_450816_-	antitoxin	NA	NA	NA	NA
AXM92356.1\|450761_451028_-	hypothetical protein	NA	NA	NA	NA
AXM91024.1\|451191_452298_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	5.0e-35	31.1
AXM91025.1\|452792_453623_+\|integrase	integrase	A0A2P1CCU8	Gordonia_phage	6.8e-53	43.7
AXM91026.1\|453619_454492_-	N-acetylmuramoyl-L-alanine amidase	NA	NA	NA	NA
AXM91027.1\|454491_454848_-\|holin	holin	NA	NA	NA	NA
AXM91028.1\|454863_455541_-	hypothetical protein	NA	NA	NA	NA
AXM91029.1\|455537_457052_-	hypothetical protein	NA	NA	NA	NA
AXM91030.1\|457051_458920_-\|tail	phage tail protein	U3PFW9	Lactobacillus_phage	6.2e-70	68.8
AXM91031.1\|458923_459154_-	hypothetical protein	NA	NA	NA	NA
AXM91032.1\|459078_459351_-	hypothetical protein	NA	NA	NA	NA
AXM91033.1\|459350_459734_-	hypothetical protein	A0A2P1CBZ9	Gordonia_phage	5.6e-18	38.1
459431:459446	attR	NA	NA	NA	NA
AXM91034.1\|459740_460151_-	hypothetical protein	NA	NA	NA	NA
AXM92357.1\|460172_460493_-	hypothetical protein	NA	NA	NA	NA
AXM92358.1\|460537_460867_-	hypothetical protein	NA	NA	NA	NA
AXM91035.1\|460866_462423_-\|capsid	phage major capsid protein	I6S2W2	Marinomonas_phage	7.6e-13	40.6
AXM91036.1\|462419_463523_-\|portal	phage portal protein	A0A2R4A099	Microbacterium_phage	2.8e-62	38.3

DBSCAN-SWA_3

974331 : 1042136

Agrobacterium_phage(30.0%)

transposase,protease,integrase

attL 975709:975725|attR 978758:978774

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AXM91379.1\|974331_975660_+\|integrase	site-specific integrase	A0A2I7SCV1	Paenibacillus_phage	1.0e-10	24.1
975709:975725	attL	NA	NA	NA	NA
AXM91380.1\|975807_976575_-	cell filamentation protein Fic	S4TP71	Salmonella_phage	2.5e-09	28.3
AXM91381.1\|976577_976769_-	hypothetical protein	NA	NA	NA	NA
AXM91382.1\|976964_977180_+\|integrase	integrase	NA	NA	NA	NA
AXM91383.1\|977899_978622_+	EcsC family protein	NA	NA	NA	NA
AXM91384.1\|978700_978937_+	macrolide ABC transporter ATP-binding protein	NA	NA	NA	NA
978758:978774	attR	NA	NA	NA	NA
AXM91385.1\|978965_979889_+	colicin transporter	NA	NA	NA	NA
AXM91386.1\|979995_985512_+	cell wall anchor protein	NA	NA	NA	NA
AXM91387.1\|985757_985991_+	hypothetical protein	NA	NA	NA	NA
AXM91388.1\|986005_986851_+	hypothetical protein	NA	NA	NA	NA
AXM91389.1\|987237_989634_+	transfer complex protein	NA	NA	NA	NA
AXM91390.1\|989638_991342_+	glycoside hydrolase	M4I0L3	Staphylococcus_phage	2.5e-17	42.5
AXM91391.1\|991356_991896_+	cobalt transporter	NA	NA	NA	NA
AXM91392.1\|991951_993319_+	molecular chaperone	NA	NA	NA	NA
AXM91393.1\|993325_995158_-	conjugal transfer protein TraG	NA	NA	NA	NA
AXM91394.1\|995170_995482_-	hypothetical protein	NA	NA	NA	NA
AXM91395.1\|995478_995787_-	aminopeptidase	NA	NA	NA	NA
AXM91396.1\|998986_1000165_-\|transposase	IS256 family transposase	NA	NA	NA	NA
AXM91397.1\|1004046_1004484_-	TnpV protein	NA	NA	NA	NA
AXM91398.1\|1004548_1004848_+	hypothetical protein	NA	NA	NA	NA
AXM91399.1\|1004877_1006815_-	hypothetical protein	NA	NA	NA	NA
AXM91400.1\|1006827_1007907_-	mobilization protein	NA	NA	NA	NA
AXM91401.1\|1007951_1009586_-	mobilization protein	NA	NA	NA	NA
AXM91402.1\|1009588_1009969_-	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
AXM91403.1\|1010417_1010666_-	DUF2442 domain-containing protein	NA	NA	NA	NA
AXM91404.1\|1010682_1010970_-	hypothetical protein	NA	NA	NA	NA
AXM91405.1\|1011322_1011646_-	hypothetical protein	NA	NA	NA	NA
AXM91406.1\|1011642_1011945_-	hypothetical protein	NA	NA	NA	NA
AXM91407.1\|1012374_1012806_+	gas vesicle protein	NA	NA	NA	NA
AXM91408.1\|1012825_1015033_+	DNA topoisomerase III	NA	NA	NA	NA
AXM91409.1\|1015084_1015594_+	hypothetical protein	NA	NA	NA	NA
AXM91410.1\|1015701_1016115_+	hypothetical protein	NA	NA	NA	NA
AXM91411.1\|1016139_1016508_+	hypothetical protein	NA	NA	NA	NA
AXM91412.1\|1016550_1017864_+	toxin HipA	NA	NA	NA	NA
AXM91413.1\|1018381_1019305_-	colicin transporter	NA	NA	NA	NA
AXM92403.1\|1019333_1019606_-	macrolide ABC transporter ATP-binding protein	NA	NA	NA	NA
AXM91414.1\|1019611_1020283_-	DNA partition protein	NA	NA	NA	NA
AXM91415.1\|1020502_1021000_-	WhiB family transcriptional regulator	NA	NA	NA	NA
AXM91416.1\|1020996_1021251_-	hypothetical protein	NA	NA	NA	NA
AXM91417.1\|1021247_1022378_-	hypothetical protein	A0A1W6JTD5	Pseudomonas_phage	3.7e-09	43.0
AXM91418.1\|1022526_1022718_-	hypothetical protein	NA	NA	NA	NA
AXM91419.1\|1022885_1023659_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
AXM91420.1\|1023850_1024096_-	transcriptional regulator	NA	NA	NA	NA
AXM91421.1\|1024283_1025282_+	peptidyl-prolyl cis-trans isomerase	A0A1V0S9I2	Catovirus	2.3e-23	44.1
AXM92404.1\|1025427_1026279_-	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
AXM91422.1\|1026475_1026982_+	ATP-binding protein	NA	NA	NA	NA
AXM91423.1\|1027018_1028170_+	amidohydrolase	NA	NA	NA	NA
AXM91424.1\|1028252_1029950_+	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	1.8e-84	35.6
AXM91425.1\|1029982_1030264_+	hypothetical protein	NA	NA	NA	NA
AXM91426.1\|1030383_1032759_+	formate acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	2.9e-149	38.8
AXM92405.1\|1032950_1033832_+	pyruvate formate-lyase 1-activating enzyme	NA	NA	NA	NA
AXM91427.1\|1033967_1034558_+	hypothetical protein	NA	NA	NA	NA
AXM91428.1\|1034547_1035834_+	ribonuclease D	NA	NA	NA	NA
AXM91429.1\|1035886_1037272_+	trigger factor	NA	NA	NA	NA
AXM91430.1\|1037477_1038881_+	chloride channel protein	NA	NA	NA	NA
AXM91431.1\|1039385_1039997_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	6.8e-42	49.7
AXM92406.1\|1040002_1040722_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.9e-36	42.6
AXM91432.1\|1040822_1042136_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	3.3e-110	50.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage