CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number
CP030852	Runella sp. HYN0085 plasmid unnamed2, complete sequence	1 crisprs	NA	4
CP030855	Runella sp. HYN0085 plasmid unnamed5, complete sequence	0 crisprs	NA	0
CP030851	Runella sp. HYN0085 plasmid unnamed1, complete sequence	0 crisprs	PD-DExK	0
CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	3 crisprs	cas4,cas2,cas1,cas6,cas3,cas5,cas7,cas8b8,WYL	51
CP030850	Runella sp. HYN0085 chromosome, complete genome	0 crisprs	csa3,PD-DExK,cas3,DEDDh,Cas9_archaeal,WYL	0
CP030853	Runella sp. HYN0085 plasmid unnamed3, complete sequence	0 crisprs	NA	0
CP030856	Runella sp. HYN0085 plasmid unnamed6, complete sequence	0 crisprs	NA	0

Cas Category Instructions

Results visualization

1. CP030852

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CRISPR-Cas detection and classification

Crispr_ID: CP030852_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030852_1

30635-30794

Orphan

Consensus_repeat	Method
ATATACATTCATACATGAATGGATATACATTTAT	CRISPRCasFinder
ATATACATTCATACATGAATGGATATACATTTAT	PILER-CR

2 spacers

The CRISPR arrays of CP030852_1

>merge|CP030852|1|30635-30794|CRISPRCasFinder,PILER-CR
CTAGTTATCCACACATGAATGGATATACATTTTATTCATTTGGAGCTTATACATGACTCAATATACATTCATACATGAATGGATATACATTTATACATGACTCAATATACATTTATCCATGAATGGATATACATTTATACATGAATGGATATACATTTAT

>CP030852|1|1|30635-30794|CRISPRCasFinder
CTAGTTATCCACACATGAATGGATATACATTTTA	TTCATTTGGAGCTTATACATGACTCA
ATATACATTCATACATGAATGGATATACATTTAT	ACATGACTCAATATACATTTATCCATGAATGG
ATATACATTTATACATGAATGGATATACATTTAT

>CP030852|1|1|30641-30794|PILER-CR
ATCCACACATGAATGGATATACATTTTATTCATTTGGAG	CTTATACATGACTCAATATACATTCAT
ACATGAATGGATATACATTTATACATGACTCAATATACA	TTTATCCATGAATGGATATACATTTATA
CATGAATGGATATACATTTAT

Protein	Signature genes	Signature genes Name	Protein_function
CP030852.1\|AXE21869.1\|38359_38563_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|213767
CP030852.1\|AXE21864.1\|35325_35808_+\|hypothetical-protein	unknown	unknown	unknown
CP030852.1\|AXE21861.1\|28261_29140_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380381
CP030852.1\|AXE21858.1\|25087_26071_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366542
CP030852.1\|AXE21860.1\|27388_28120_-\|DUF1080-domain-containing-protein	unknown	unknown	gnl\|CDD\|368908
CP030852.1\|AXE21871.1\|41164_41725_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378964
CP030852.1\|AXE21870.1\|38675_40406_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379044
CP030852.1\|AXE21908.1\|33400_33637_-\|conjugal-transfer-protein	unknown	unknown	gnl\|CDD\|372636
CP030852.1\|AXE21857.1\|23009_23798_-\|phytanoyl-CoA-dioxygenase-family-protein	unknown	unknown	gnl\|CDD\|368580
CP030852.1\|AXE21855.1\|20472_21417_-\|ParA-family-protein	unknown	unknown	gnl\|CDD\|379293
CP030852.1\|AXE21854.1\|19615_20458_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319261
CP030852.1\|AXE21868.1\|38035_38281_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274416
CP030852.1\|AXE21853.1\|16493_19136_-\|heme-binding-protein	unknown	unknown	gnl\|CDD\|274225
CP030852.1\|AXE21859.1\|26024_27392_-\|gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
CP030852.1\|AXE21865.1\|35807_36020_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240327
CP030852.1\|AXE21856.1\|21781_22588_-\|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl\|CDD\|224007
CP030852.1\|AXE21862.1\|29162_30356_-\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
CP030852.1\|AXE21863.1\|33120_33348_-\|hypothetical-protein	unknown	unknown	unknown
CP030852.1\|AXE21866.1\|36063_36249_+\|hypothetical-protein	unknown	unknown	unknown
CP030852.1\|AXE21867.1\|36494_37019_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP030852.1\|AXE21869.1\|38359_38563_-\|transcriptional-regulator	gnl\|CDD\|213767	TIGR03070, couple_hipB, transcriptional regulator, y4mF family. Members of this family belong to a clade of helix-turn-helix DNA-binding proteins, among the larger family pfam01381 (HTH_3; Helix-turn-helix). Members are similar in sequence to the HipB protein of E. coli. Genes for members of the seed alignment for this protein family were found to be closely linked to genes encoding proteins related to HipA. The HibBA operon appears to have some features in common with toxin-antitoxin post-segregational killing systems. [Regulatory functions, DNA interactions].	1.15883e-11
CP030852.1\|AXE21870.1\|38675_40406_+\|hypothetical-protein	gnl\|CDD\|379044	pfam13155, Toprim_2, Toprim-like. This is a family or Toprim-like proteins.	3.27326e-09
CP030852.1\|AXE21861.1\|28261_29140_+\|hypothetical-protein	gnl\|CDD\|380381	cd06976, cupin_MtlR-like_N, AraC/XylS family transcriptional regulators similar to MtlR, N-terminal cupin domain. MtlR is a Pseudomonas fluorescens protein that acts as a transcriptional regulator of the mannitol utilization genes. It has an N-terminal cupin domain (represented by this alignment) and a C-terminal AraC/XylS family helix-turn-helix (HTH) DNA-binding domain. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	4.13604e-39
CP030852.1\|AXE21858.1\|25087_26071_-\|hypothetical-protein	gnl\|CDD\|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	1.42311e-11
CP030852.1\|AXE21860.1\|27388_28120_-\|DUF1080-domain-containing-protein	gnl\|CDD\|368908	pfam06439, DUF1080, Domain of Unknown Function (DUF1080). This family has structural similarity to an endo-1,3-1,4-beta glucanase belonging to glycoside hydrolase family 16. However, the structure surrounding the active site differs from that of the endo-1,3-1,4-beta glucanase.	1.73547e-50
CP030852.1\|AXE21871.1\|41164_41725_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|378964	pfam12833, HTH_18, Helix-turn-helix domain.	7.26026e-19
CP030852.1\|AXE21908.1\|33400_33637_-\|conjugal-transfer-protein	gnl\|CDD\|372636	pfam13572, DUF4134, Domain of unknown function (DUF4134). Based on Bacteroides thetaiotaomicron gene BT_0095, a putative uncharacterized protein As seen in gene expression experiments (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE2231), It appears to be upregulated in the presence of host or vs when in culture.	4.25557e-19
CP030852.1\|AXE21857.1\|23009_23798_-\|phytanoyl-CoA-dioxygenase-family-protein	gnl\|CDD\|368580	pfam05721, PhyH, Phytanoyl-CoA dioxygenase (PhyH). This family is made up of several eukaryotic phytanoyl-CoA dioxygenase (PhyH) proteins, ectoine hydroxylases and a number of bacterial deoxygenases. PhyH is a peroxisomal enzyme catalyzing the first step of phytanic acid alpha-oxidation. PhyH deficiency causes Refsum's disease (RD) which is an inherited neurological syndrome biochemically characterized by the accumulation of phytanic acid in plasma and tissues.	6.94882e-40
CP030852.1\|AXE21855.1\|20472_21417_-\|ParA-family-protein	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	3.48827e-57
CP030852.1\|AXE21854.1\|19615_20458_-\|hypothetical-protein	gnl\|CDD\|319261	cd16404, pNOB8_ParB_N_like, pNOB8 ParB-like N-terminal domain, plasmid partitioning system protein domain. archaeal pNOB8 ParB acts in a plasmid partitioning system made up of 3 parts: AspA, ParA motor protein, and ParB, which links ParA to the protein-DNA superhelix. As demonstrated in Sulfolobus, AspA spreads along DNA, which allows ParB binding, and links to the Walker-motif containing ParA motor protein. The Sulfolobus ParB C-terminal domain resembles eukaryotic segregation protein CenpA, and other histones. This family is related to the N-terminal domain of ParB (Spo0J in Bacillus subtilis), a DNA-binding component of the prokaryotic parABS partitioning system and related proteins.	0.00332396
CP030852.1\|AXE21868.1\|38035_38281_-\|hypothetical-protein	gnl\|CDD\|274416	TIGR03071, couple_hipA, HipA N-terminal domain. Although Pfam models pfam07805 and pfam07804 currently are called HipA-like N-terminal domain and HipA-like C-terminal domain, respectively, those models hit the central and C-terminal regions of E. coli HipA but not the N-terminal region. This model hits the N-terminal region of HipA and its homologs, and also identifies proteins that lack match regions for pfam07804 and pfam07805.	8.20505e-19
CP030852.1\|AXE21859.1\|26024_27392_-\|gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.27473e-26
CP030852.1\|AXE21865.1\|35807_36020_+\|hypothetical-protein	gnl\|CDD\|240327	PTZ00243, PTZ00243, ABC transporter; Provisional.	0.00795266
CP030852.1\|AXE21856.1\|21781_22588_-\|sugar-phosphate-isomerase/epimerase	gnl\|CDD\|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	1.25632e-05
CP030852.1\|AXE21862.1\|29162_30356_-\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	6.52618e-20
CP030852.1\|AXE21853.1\|16493_19136_-\|heme-binding-protein	gnl\|CDD\|274225	TIGR02604, Piru_Ver_Nterm, putative membrane-bound dehydrogenase domain. All proteins that score above the trusted cutoff score of 45 to this model are large proteins of either Pirellula sp. 1 or Verrucomicrobium spinosum. These proteins all contain, in addition to this domain, several hundred residues of highly variable sequence, and then a well-conserved C-terminal domain (TIGR02603) that features a putative cytochrome c-type heme binding motif CXXCH. The membrane-bound L-sorbosone dehydrogenase from Acetobacter liquefaciens (Gluconacetobacter liquefaciens) (SP\|Q44091) is homologous to this domain but lacks additional sequence regions shared by members of this family and belongs to a different clade of the larger family of homologs. It and its closely related homologs are excluded from the this model by scoring between the trusted (45) and noise (18) cutoffs.	1.89452e-21

>CP030852.1|AXE21862.1|29162_30356_-|replication-initiation-protein
MAKKTNSEYIEDLQNNSDVVILNNPIATPTFIRQLSKSKKAEINEVYTPKLFYEIASRLKPADLENLSRNTNIVLTLEIKDFLKSIQTTNTSGYSYLIDSIKMLQTTLVEWIEGRETIIVPIISQSVHKHDSGKIDLYISHDLAKQILQVKETENFSFFKKNVFALQTTRSIKLFPFFSSWKNYGRPIDVDLKSFKEKLGFNKVVYSRFSSLKKHVIDPAIHEINEKTDLFVKYELLGNNLDSKKPRVTGIRFWVWEKKNVKALEEKKAKQGSGEAIMDVDKYIEQVTADYKTRLRKHADEFYDRLLGNVANKSHYGELVIKFQGTALVNQFNMITDVEWMMKEFFRMFPYHAESLRSLSAIRSHIEITEQESKQRGFLLYFELNEGFDLKVTKVEV
>CP030852.1|AXE21861.1|28261_29140_+|hypothetical-protein
MRPDRLTVPQTDYRSFDIRHEQVPYFTNPWHFHPELELNYIVESTGTRFIGQSVERFESGEIVLLGKNLPHYWKNDASYYQPSTAPKAQAIILRFAEDFAGAPFFKLPETKHIEALFEKAIYGLKLLEPLRSQVAQQLHQLLEAVGFSQLMTFVGLLDTLAKSNDLAVISPNYMPISTLTKNNERMNRVVAYLLEHFTEPITLQIVAELGSMNESAFCRYFKAQTGQTLNQYITDLRIRYACELLSKSKDSITQICFQVGFENVSHFIHVFKKARHQTPFEFRQKVIGKILI
>CP030852.1|AXE21860.1|27388_28120_-|DUF1080-domain-containing-protein
MYYLRLMAIILWFLGVMGCNAQKPNTLTQTEQKTGWVLLFDGKTTAGWRGAYSSVFPKHGWVVKNGELRGELSDGAESGDVGDIVTLKKYRNFELIFDWKLGKGGNSGVKYFIEERQPKPEKGSQTGYEYQLIDDADYIYNGKPLPQDLKTASIYDVMAAKKPDIKVEVWHSSRIVVNGNHIEHWLDGKKVLDINRNSEAFKQGVQQSKFKDYQGFASIPEGHILLQDHGHSVAFKNIKLKEL
>CP030852.1|AXE21859.1|26024_27392_-|gfo/Idh/MocA-family-oxidoreductase
MNRRNFLKNTGLATASVGFPTIVPASVFGKNAPSNRITVGLIGTGRQGYGQNLQGAEQKSLGAKIPGLLDIADAQIVAACDVDSWRLDKAKTTIEAHYAKNTISGKYKGCATYVDFREIIARKDIDAVMISTPDFWHVPMGILASKAQKHISCEKPLSMSVHQGRELVDALKKYGVVNRTDSEFRSIRPQNLAVELVRNGRIGKLQKIEIVFPSDPPPVPSQVDMPVPKGLNYDLWLGPMPYVPYTDMRVHTPFDILKRPNWMRVDTYAQGMISNWGAHYFDMAQWANNSEYSGPVEVEGKGEFPKSLWNTMINFQVTYRYANSVEMTCLQSPTSRPSIKYIGSEGWIHVENYPGKLTASNPKMLDSKPMGSELDLSKTLWDKTDFIEAVKTNRKTLEPIEVGHRTISISQIGLIAAQVGAGEKLKWNPEKELFEGNNYANALLAAPLARKPWTM
>CP030852.1|AXE21858.1|25087_26071_-|hypothetical-protein
MPYWRLRWQENLGRCKYFNRAGGPAQIMQKMALRVYFFLLFFWLGCAAIASAQKIKNDFFTLHNIIRGDSTYNTFDKQVELVKKAGFDGIEINQTQSFEGMKAALDKHQFAGSYFYVRVELKEPYIDMRLEEYIQQLKGSKTIIAPFIIVDAARFKPSSHGADTLVVRLVTQLSDWAKAAGLQVAIYPHHGFYVERTNHAMLLIKQINRKNVGLTFNLCHWLATTSAAERTQLKPHLKELKPYLKMITICGANDVMTSQKTIWDDYILPLGTGSFDTYGLLKYVVKDLKFKGPIGIQCYNIKGNKPQLVQNTMAIWKGYKSRLEYEQ
>CP030852.1|AXE21857.1|23009_23798_-|phytanoyl-CoA-dioxygenase-family-protein
MEFTKEHLDTYHRDGYVVVRNFFTQEEVDLLYKIAIKDDVMRKKSYDRTDASGLKTKLALWYSLDESLYSKFARSERIVRGVEQILGGKAAHYHSKLMQKEPKTGGAWEWHQDYGYWYKNNGFLLPDMLSVLTALTPATKENGCLQMIRGSHKMGRVEHGFAGEQVGADMEKVNEALKIMPLDYLEMAAGDTAFFHCNTLHASAANLSDKPRWSIITAYNLSSNKPYKDVHTSSYTPIEPFKGDLLAEDAVSITDNADFLVK
>CP030852.1|AXE21856.1|21781_22588_-|sugar-phosphate-isomerase/epimerase
MKIKFYAPAWGNMLPFDTFCKNVKEVGYDGVEMALPLEVKKKQEILDIFKQYDLEFIGQYYQSFERDLDEHAENYEKYLRHLSSANPVFINCQSGKDYFSFEQNKRLFEVAARISKETGVKIIHETHRGKSLFAAHITQHYLTQISDLRITLDISHWCNVHESLLADQPEAVELALSHTDHIHTRIGHIEGPQVNDPRAPEWKETFETHLLWWDKIVEIHRKNGTQLTMNTEFGPATYMPVLPYTQQPVASQWEINVFMLNLLKKRYE
>CP030852.1|AXE21855.1|20472_21417_-|ParA-family-protein
MLTQDIVFRFLRSKPALNHSQIEKEAGLPSKTLYKAQGGLINLNENHLAKLGPVLRNYGFSEEQFSKAKVISIVNHKGGVGKTTSTINLGKALSLLGNRVLMLDMDSQGNLSQCFGIHQPETQIIDSLLDKRDLPIIEIESKLHLSPSDIQMAYRELELVNSIGSEKRLSNKLAPLLSEYDFILIDCPPALNVLTTCALVASHECLIPIQPEASAYHGVENLFNRIFEIREHLNYSLRVRGIFFTMVHKNQSVHRTMIDHIRQVYGHFTIFDTLIETSTVIKQSQVAKQDLFEYSPKSNSANQYLALAQELATA
>CP030852.1|AXE21854.1|19615_20458_-|hypothetical-protein
MAKDFMSGIKKATAQLPGSAFSEVEKIKKQLIILEELRQFITPLTTDELAMLEANILSQGCKDPLAVWETTRKVAGLDDSEEVAYVLIDGHNRYTICEKYTIDFKIVLLKFDDLEKVKDYMIDFQLGRRNLSPEQLSFFRGLRYNREKGRKGKYDREEGGIDISKQLADEYKVSQRTIKNDGNFAKGISKFSPELRQQVLAGNAALKKTTIQELGKREDVAEGAFQSFESLSEPSKTESSPFLEELAQRKKEVARIATNMVSKSDYALLVQKVKELKKYL
>CP030852.1|AXE21853.1|16493_19136_-|heme-binding-protein
MLKVSYTLIASLLFLYLNGTQPWKTETPKNYTKTTRIDSLRNATSWPEELNISNFSSADITPSPACIAVAPSGEVYVGVDKMGSLGKKPGNGSIVRLVDTNNDGKIDQHTTYALADNPRGILPIGDRVYVLHTVFSKETGIATGMNLVVFEDKNNDGVADGPSSLLIEHISSPKFLQSRGTDHATNGIRMGIDGWIYIAVGDFGFHNATDRSGKKMTMLGGGIVRVRPDGTEMEVYTHGMRNIYDVAIDPYMNIFARGNTNDGGGWNIRFSNQIQSGEYGYPVLFKHFTDEIIPALIDLGGGSGTGALFMDDATWPAKYNNVPMMADWGRSQLYIHRVTPDGASFTQQEEPFIKLAQITDIDIDASGRAYLSAWDGAGYSGNPKKGFVVRAVPKNWVYKPFADLKKASVSKLTAYLASGSAVARLAAQQELLTRPTKKYSKAVWKLTTDKKKPLAARVAALFTYAQATGVEGVANLLTLTQDADLKEFALRALADRKGNLTSVPTEPFLNGLKDSSPRVRVAATVGLGRLGRSEAADALLQVAVPSTFAAPAIGTEGPHATPNSAIIPAHIAVRSLVSLNAIDACVKAIGTANSTIALWALRYMHDSKAANGLMAAYQRTNDESLKKQILTTLSRIYKKEAEYDGSWWWSTRPDTHGPYYKAITWESSAAIKDFLVAEWQKSTDKQFYIDLNSRHRMEIPEFGKEEPVAVKEEVKVDLEKIRNKKGQVGEASIEDVMLAMAKFQGDAALGKTIFTQQGCIACHSLSKGEVMKGPFMGQIGSIMNREQIAESILKPNASISQGFSTVLITAKRNKSYMGFITEESASKVVLRDITGQVTTLKTSDIVSRKEMETSMMPSGLVNALSYEEFASLLTFLAQQK
>CP030852.1|AXE21863.1|33120_33348_-|hypothetical-protein
MNDHTFAKSVDLTKKSGFSRVRIDKYLSEPLHNNHSMFVTFTYLVCGFMSLIEGLRIYNRWQLDERELITVEIWR
>CP030852.1|AXE21908.1|33400_33637_-|conjugal-transfer-protein
MQSDAQVIDQQAAALQAYFTSVTTIIYVIAAIVGLVCGFRIYSKWQNGDQDTQKAALGWMSAILFILAIAASLQYVFF
>CP030852.1|AXE21864.1|35325_35808_+|hypothetical-protein
MSGLIIKEKEGNALGGKLLLIIAILLLIFHFLWFCHVIIAESLPIRGFIYTFLTKLHRQFKLFNTSILSKIMIYFLIFLNLLGLKGKIVPNVKRQKIMADAPLWTALFMGSIFLLYLKEAFTPILIDTFYIIVTLVGSLLLVKPGQHMSRLLLPNLKMIF
>CP030852.1|AXE21865.1|35807_36020_+|hypothetical-protein
MYRTKNSLKMKRLYLTNQDFLPLPRKWREGLVDIVNPFGLTMVLGLPGSGKSYTILKPSLWQFIYEGYTA
>CP030852.1|AXE21866.1|36063_36249_+|hypothetical-protein
MKSVVIINIIEEILASNISTLKQYEFIGHFVDNFGEEFDIKNIQSFYECIERPAQKMENCL
>CP030852.1|AXE21867.1|36494_37019_+|hypothetical-protein
MNPRGRPKLAADEKGSYTPILVGEDVLKTLQISSEKPEEQAELKAKLTIVKEHPEASEYYWKLVFTYSFFVYKNRRMTDAIFERSDTMTLENIKKMNLKQLAEIVNIEYHNFKNMYSGRGNAKNLLQYQSFLYENGVNFISLQYMDTLINKAYSYYQLLKSDKYTSEELKNLFF
>CP030852.1|AXE21868.1|38035_38281_-|hypothetical-protein
MTLTSLAPILSLTLPISNQEYKSPYLFPLFYGLLSKGYNRAIQCRLLKIDENDDFGLLLAIAHSDTIGAVRVMEQPKKTDH
>CP030852.1|AXE21869.1|38359_38563_-|transcriptional-regulator
MTLIQLGETIRQRRQRLDIRQNDLADLAEIGLRTVIAVENGTGNPSFQTLTKIVEVLGLELNLTVKL
>CP030852.1|AXE21870.1|38675_40406_+|hypothetical-protein
MRDLEQIKRILDLEVVLQHYGYRFVKSKSSTVSRIYRKGEQRLSVIVDGGFAAKFFADLNDPQFKGDIFKFMERMEHGNYRQIFEKIELMMAQSGTLPDVFAKKIDLPEQSVVEPVSDRRREDIRLREQDLYRKFQITPLTDTEYLESRYISKDVLFSKEFEGRLKNVTFDNGVIQYANTAFPMYARNGNIQSMDIRNMAYKAFPKGERGEALWRSNQFFEAKRALKAENGLEIPVGTLGTLYRRDTENFVFMYGEVGKEMRLIVPYEQAKTGLNEVPVHRIIISESPIDAISLKQLNPEKANERRLYVATCGQPSGKQLAFLQEILNQNPQAQFVIAQDGDNAGLRFAVNYLVLDHPSEDPEMKIKPYLMFSSTVEQQPKKIKESTQTQESTGMNRLKLELRYPLAAGARKAQELNEGFIRALAEEMNLFASRIPKNCNDKSQKNKEQQIEHHLQNIPITETMLDENMQYLITRTEIHFLNNAELTTKVLKRISDEIENRQGQKLFQFVCLTPQQKDLNNVLKELNGQALPSSHPLTLPELPVIKSYQDIQKDKKAGKENVEHQWFMSNNNKIIF
>CP030852.1|AXE21871.1|41164_41725_-|AraC-family-transcriptional-regulator
MKLYIKFMVSLRCKMVVEATLKKLRLPYKTIDLGMVELLEEITPPQREILKEQLLQSGLELLNDKKSILIEKTKAVIIKMIHYENEVPKVNYSDYISEKLGYDYTYLSNIFSEHKGMTIQQFIILHKIERVKELLLYDEINLTEIAYRLHYSSVAHLSTQFKKVTGVPPSYFKKLWQKREGNLENM

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP030852_1	1.1\|30669\|26\|CP030852\|CRISPRCasFinder	30669-30694	26	NZ_CP030852	Runella sp. HYN0085 plasmid unnamed2, complete sequence	30669-30694	0	1.0
CP030852_1	1.2\|30729\|32\|CP030852\|CRISPRCasFinder	30729-30760	32	NZ_CP030852	Runella sp. HYN0085 plasmid unnamed2, complete sequence	30729-30760	0	1.0
CP030852_1	1.3\|30680\|27\|CP030852\|PILER-CR	30680-30706	27	NZ_CP030852	Runella sp. HYN0085 plasmid unnamed2, complete sequence	30667-30693	0	1.0
CP030852_1	1.4\|30746\|28\|CP030852\|PILER-CR	30746-30773	28	NZ_CP030852	Runella sp. HYN0085 plasmid unnamed2, complete sequence	30733-30760	0	1.0
CP030852_1	1.2\|30729\|32\|CP030852\|CRISPRCasFinder	30729-30760	32	NZ_CP030852	Runella sp. HYN0085 plasmid unnamed2, complete sequence	30685-30716	2	0.938
CP030852_1	1.4\|30746\|28\|CP030852\|PILER-CR	30746-30773	28	NZ_CP030852	Runella sp. HYN0085 plasmid unnamed2, complete sequence	30689-30716	2	0.929
CP030852_1	1.4\|30746\|28\|CP030852\|PILER-CR	30746-30773	28	NZ_CP030852	Runella sp. HYN0085 plasmid unnamed2, complete sequence	30755-30782	4	0.857
CP030852_1	1.3\|30680\|27\|CP030852\|PILER-CR	30680-30706	27	NC_011262	Borrelia duttonii Ly plasmid pl31, complete sequence	12184-12210	6	0.778
CP030852_1	1.4\|30746\|28\|CP030852\|PILER-CR	30746-30773	28	MG592606	Vibrio phage 1.240.O._10N.261.52.F8, partial genome	36026-36053	6	0.786
CP030852_1	1.2\|30729\|32\|CP030852\|CRISPRCasFinder	30729-30760	32	MG592606	Vibrio phage 1.240.O._10N.261.52.F8, partial genome	36022-36053	9	0.719

1. spacer 1.1|30669|26|CP030852|CRISPRCasFinder matches to NZ_CP030852 (Runella sp. HYN0085 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcatttggagcttatacatgactca	CRISPR spacer
ttcatttggagcttatacatgactca	Protospacer
**************************

2. spacer 1.2|30729|32|CP030852|CRISPRCasFinder matches to NZ_CP030852 (Runella sp. HYN0085 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

acatgactcaatatacatttatccatgaatgg	CRISPR spacer
acatgactcaatatacatttatccatgaatgg	Protospacer
********************************

3. spacer 1.3|30680|27|CP030852|PILER-CR matches to NZ_CP030852 (Runella sp. HYN0085 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tattcatttggagcttatacatgactc	CRISPR spacer
tattcatttggagcttatacatgactc	Protospacer
***************************

4. spacer 1.4|30746|28|CP030852|PILER-CR matches to NZ_CP030852 (Runella sp. HYN0085 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gactcaatatacatttatccatgaatgg	CRISPR spacer
gactcaatatacatttatccatgaatgg	Protospacer
****************************

5. spacer 1.2|30729|32|CP030852|CRISPRCasFinder matches to NZ_CP030852 (Runella sp. HYN0085 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.938

acatgactcaatatacatttatccatgaatgg	CRISPR spacer
acatgactcaatatacattcatacatgaatgg	Protospacer
*******************.** *********

6. spacer 1.4|30746|28|CP030852|PILER-CR matches to NZ_CP030852 (Runella sp. HYN0085 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.929

gactcaatatacatttatccatgaatgg	CRISPR spacer
gactcaatatacattcatacatgaatgg	Protospacer
***************.** *********

7. spacer 1.4|30746|28|CP030852|PILER-CR matches to NZ_CP030852 (Runella sp. HYN0085 plasmid unnamed2, complete sequence) position: , mismatch: 4, identity: 0.857

gactcaatatacatttatccatgaatgg	CRISPR spacer
gaatggatatacatttatacatgaatgg	Protospacer
** * .************ *********

8. spacer 1.3|30680|27|CP030852|PILER-CR matches to NC_011262 (Borrelia duttonii Ly plasmid pl31, complete sequence) position: , mismatch: 6, identity: 0.778

tattcatttggagcttatacatgactc	CRISPR spacer
tattcatttggagtttatacaaaaaaa	Protospacer
*************.******* .*

9. spacer 1.4|30746|28|CP030852|PILER-CR matches to MG592606 (Vibrio phage 1.240.O._10N.261.52.F8, partial genome) position: , mismatch: 6, identity: 0.786

gactcaatatacatttatccatgaatgg	CRISPR spacer
aatgaaatacacatttatccatgactgg	Protospacer
.*.  ****.************** ***

10. spacer 1.2|30729|32|CP030852|CRISPRCasFinder matches to MG592606 (Vibrio phage 1.240.O._10N.261.52.F8, partial genome) position: , mismatch: 9, identity: 0.719

acatgactcaatatacatttatccatgaatgg	CRISPR spacer
aggaaatgaaatacacatttatccatgactgg	Protospacer
* . .*.  ****.************** ***

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP030854

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: CP030854_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030854_1

11474-11672

Unclear

Consensus_repeat	Method
AACTATAAGAAAAATCACACTTTTGGAAAAA	PILER-CR

2 spacers

cas4,cas2,cas1,cas6,cas3,cas5

The CRISPR arrays of CP030854_1

>merge|CP030854|1|11474-11672|PILER-CR
AACTATAAGAAAAATCACACTTTTGGAAACTCTGACTTTAAAAAATCGGTAAATAGGAATCTCCCTTCTTCAATCATAAGAAAAATCACACTTTTAGAGGTATAATATTTATAATATACTGATAATCAAGAGATTTTATTTAAACATATTAAACGACTTTTTTTGTCTAACTATAAGAAAAATCACACTTTTGGCAAAA

>CP030854|1|1|11474-11672|PILER-CR
AACTATAAGAAAAATCACACTTTTGGAAACTCTGA	CTTTAAAAAATCGGTAAATAGGAATCTCCCTTCTTCAATC
ATAAGAAAAATCACACTTTTAGAGGTATAATATTT	ATAATATACTGATAATCAAGAGATTTTATTTAAACATATTAAACGACTTTTTTTGTCTAACTATAAGAAAAA
TCACACTTTTGGCAAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP030854.1\|AXE21941.1\|21448_22438_-\|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187766
CP030854.1\|AXE21937.1\|15726_16401_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225995
CP030854.1\|AXE21971.1\|16429_16792_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376574
CP030854.1\|AXE21930.1\|1999_2932_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184751
CP030854.1\|AXE21938.1\|16889_17393_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225995
CP030854.1\|AXE21944.1\|25691_26399_-\|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	gnl\|CDD\|273860
CP030854.1\|AXE21940.1\|21112_21403_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
CP030854.1\|AXE21943.1\|23337_25695_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
CP030854.1\|AXE21934.1\|10123_10441_-\|hypothetical-protein	unknown	unknown	unknown
CP030854.1\|AXE21970.1\|8630_9464_-\|hypothetical-protein	unknown	unknown	unknown
CP030854.1\|AXE21932.1\|3699_5232_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|185760
CP030854.1\|AXE21939.1\|20540_21113_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768
CP030854.1\|AXE21942.1\|22660_23326_-\|DNA-repair-protein	cas6	cls000004_cas6_CAS-I:CAS-III	gnl\|CDD\|380073
CP030854.1\|AXE21936.1\|12115_13573_+\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
CP030854.1\|AXE21935.1\|10495_11155_-\|chromosome-partitioning-protein-ParA	unknown	unknown	gnl\|CDD\|222854
CP030854.1\|AXE21931.1\|3274_3565_+\|hypothetical-protein	unknown	unknown	unknown
CP030854.1\|AXE21933.1\|5260_8569_-\|SusC/RagA-family-protein	unknown	unknown	gnl\|CDD\|274948

Protein	Function_ID	Function_description	E-value
CP030854.1\|AXE21941.1\|21448_22438_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.51346e-89
CP030854.1\|AXE21937.1\|15726_16401_-\|hypothetical-protein	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.94495e-19
CP030854.1\|AXE21932.1\|3699_5232_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	5.5718e-45
CP030854.1\|AXE21930.1\|1999_2932_-\|hypothetical-protein	gnl\|CDD\|184751	PRK14571, PRK14571, D-alanyl-alanine synthetase A; Provisional.	2.52645e-24
CP030854.1\|AXE21938.1\|16889_17393_-\|hypothetical-protein	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.33527e-10
CP030854.1\|AXE21944.1\|25691_26399_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	1.6617e-12
CP030854.1\|AXE21940.1\|21112_21403_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.68386e-20
CP030854.1\|AXE21943.1\|23337_25695_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	2.00663e-63
CP030854.1\|AXE21971.1\|16429_16792_-\|hypothetical-protein	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	3.65157e-06
CP030854.1\|AXE21939.1\|20540_21113_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	8.46678e-25
CP030854.1\|AXE21942.1\|22660_23326_-\|DNA-repair-protein	gnl\|CDD\|380073	pfam17955, Cas6b_N, Cas6b N-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. Four Cas proteins (Cas5, Cas6b, Cas7 and Cas8b) are proposed to form a Type I-B Cascade complex that mediates the antiviral defense. This is the N-terminal domain found in Cas6b proteins. Cas6b is a member of Cas6 RNA processing endoribonucleases found in bacteria and archaea whose RNA substrates have a wide range of structural features. Cocrystal structures of Cas6 from Methanococcus maripaludis (MmCas6b) bound with its repeat RNA revealed a dual-site binding structure and a cleavage site conformation poised for phosphodiester bond breakage.	9.82647e-39
CP030854.1\|AXE21936.1\|12115_13573_+\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	2.9345e-31
CP030854.1\|AXE21935.1\|10495_11155_-\|chromosome-partitioning-protein-ParA	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	4.06571e-43
CP030854.1\|AXE21933.1\|5260_8569_-\|SusC/RagA-family-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0

>CP030854.1|AXE21935.1|10495_11155_-|chromosome-partitioning-protein-ParA
MIITVGGIKGGSGKTTVATNLAIYISQRGGDVLLVDADDQETATDFTAWREETKMGEVGYTAVKLTGDQVRTQVAKLKSKYQYVVIDTGGRDTTSQRAALFISDIYLLPFNPRSFDVWTVGKVEKLIMEIRAVRPAELLAFSFINRADARGSDNNDAAELLAQSEVMEYLEMPLGNRKAFSHAAAKGLGVTELLPVDEKAVNELTSLFNKVLSHTNALI
>CP030854.1|AXE21934.1|10123_10441_-|hypothetical-protein
MAVSAPPKKKVPETPPVVSEEEITKVINKGGSPVNKLAKTRTRDKTKPIRAIAVSLTSEEIDSIISLRNQRPSPSRTKKIPISLHDWILEAVQEKIERERKKYQM
>CP030854.1|AXE21970.1|8630_9464_-|hypothetical-protein
MAVLFLGTADMEVKIVASTTIDSLGACQGVSYLLGKVYLYGDREVGMIRTYALNSNQLIYTGQEIKLTQNGQDVINHPTGIAHNGSKHTFVGNSIRLNPEGTQWKAVIYAVDWEGLQRTKTLDGNLLNVIEDDICIQGTRPEYVQYEGKWYVATADYGPKSNEVRLYDPQILSKAKKTSEAGVLFKKFSCSAWVQNLHWIPSKGILVLIQNQIEGRKWRFTFIDLKKSVASGQQQVLNVVDIDKSDELEGFTLLEGSSTGMAVTSSRHQNVHLVTVK
>CP030854.1|AXE21933.1|5260_8569_-|SusC/RagA-family-protein
MNIYKTPTKSWMCFCILFLGLTFLHQFPASATKLQQAIKVTGIITDEANQPLPGVSIVEKQTRKGTVSDEQGKFSLDVSTEAVLVISSVGFVPQEVVINGQTSLTIKLKEDINMLNEVVAVGYQILRKSDVTGAISNVKARELNLAAPTLGQALVGKLAGVQVSQVSGAPYVSTKIRVRGIGSINASSDPLYVIDGFPAGNDVFINPNDIESIDILKDAASAAIYGSRASGGVVIITTKRGKEGNGKMEYDYQYGVHQLAKKVKLLNSEQFAQLLIDARNNTYRDLYENSGKTWNNSMYSDDNATRVSKVGNASAVSIPTDIYDFANQKLIAPKYNTDWQNELYRNAPVSRHNLTFSGGNKGGRYLVSLGYQNQQGIIVATKQERLNFRVNVDGDLTEKLKVGASIFVTSTNGREVQEGRFNQGVVLGALIYPPTFRAYDDNGVLLKNQVAAQQPTFGYQTVENPVALALETNINRRGLRANYNGNLTYELLPGLSAKANIGLQTYNEKYEYYLPTSLSSGNNPPYSTQSYAAARATAQTLATTNLLGEFTANYTKQFGEHGINLLAGYTAQKYNSDLISVSAQGFQNDLIQEITAKGADPANFFLNGGTGKVEETLLSYLARAEYRFASRYYITAAFRRDGSSRFGPLNRWGAFPSVSAGWNISEESFYNNMLGEASTLKLRASWGLTGNYNIGNYNYLQTMANPSGTVFGNGTINTAVWAGPIKDQRLGWESTSQYNVGLDVGLLRNRLSFIFNAYLSNSYNLLFNQPVSAISGTSTILTNLRDSKVQNKGVELQIDGRLVSTKEFKLNLSGNISFNRNKVLNMGGANTIITNGAERSYLTHITQEGQPIGMFYGFKVIGMVREKDMENIAVDNANYNASKQSFPAGYVLKGPARSTASSNPLRPGDLIFEDVNKDGVVNDADKQVIGTPYPKFTYGFSLNASYRDFDLGAAFNGVYGNQVLDGQDYYVYNMEASGNQYVDVINRYRSEAEPGNGLVYRAARGGTQSNSTRLSTFYLQSGSFFRCTNLSLGYNLPTKWLGKWKVEGLRVYANVNNAFTMTKYKGYNPEVDYNGGANLTPGVDYGMYPLARAYNIGAKLTF
>CP030854.1|AXE21932.1|3699_5232_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTIRNSILCLCLTLGAMSCNDNFLVETDPNSVATSNYFKNENDVLLAVNGAYQALRNNNGLAEGSMLYSEERSDNTGRNDNQSNAGEPFQFNDFSLLPSNTYLKTHWLALYQIITRTNLVLDGIEKVTFSNATTKAQYQAEAKFIRALVYFHLVRKWGDVPLVIKPLSSSDEVKANTAREKKDKVYAQIVADLTDVVNSSLPDHQPVANKGRVSKVAGMALLGQVYLTMATTLDAANRTTNLNQAKTYLTGAYEKRTFGLLKEIAYTDVFDVAKKSTNPEIIFQIVYKQGDINYASNIAVSTQAQGENINSLRTTTGTGGNVTPDLVKEYEEGDLRKDFSIKYANAANVKDYFITKYRDVSAAAGANGYGGNDWILMRYADVILMLAEVNLYLGNDAAAIGFLNQVRERAKMPLYEVAKEAPAYKAKFPTLKMAILHERRIELAFENHRWFDLLRFFTPAELVTYMGTKLQADFGAAKISNFGLKDYYYPIPFDEFKLDPVKMYQNEGY
>CP030854.1|AXE21931.1|3274_3565_+|hypothetical-protein
MKSKIKAQASEIAKKIADVMIEEATSKKIKKAVNKTSEKLAKRIVKIKQKEAKEKDKVEKKAEKKVLKAAKKVSQEKKVKKVAKVSKKNEDATPIA
>CP030854.1|AXE21930.1|1999_2932_-|hypothetical-protein
MKLLYLYSDSDFTPWRENINAATIASLIQATPDNVQTFVTHFVGFTAEFADFLRQFDLIFNVCYGYGVADQVEVVRWLDWHGIKHTASSYSTQLLAMDKALLPDMCMQVGVNTPRILLPNELFEFSSTTTFIAKHRYGSLHRNMLFFKKDNIPSQQLNSLESYIIQPYIEGREFTVAVIPDKNGLNPECLPPLEIIPNDGRAIYVAGQNYGPTYKDFQPQLDEHLYDMMTEGVLELHKLLEIKGMSRTDIRIANDEVYILDINTMPNLDPQRSYLPALANHHRIQLRELIERTIKSALIWYERQLVQQPD
>CP030854.1|AXE21936.1|12115_13573_+|replication-initiation-protein
MAKKELPKRRKQDLQERYTIRIQGGKSGLVEATSKMDIHEFRVFATMLTMVLPEDEDFTTYELRVQDIIKLFSLKKDGRYYELVRDAAHKLLDRKFVIYEMKNGEEYKTTINLITETSEPVSEINKNHILLQFSPKLKPYLLQLKKEYLTIDIRNIQDISSPYSVKLYMVLKHQQRLGNYKVKYPIERLRQILAIEEGEYGLYGSFKQQVIRRTLSDIEKYTDLSVLKIEEEKAGRSVSAIIFHVVEKEAQRQNEIKIKKQQHNILKKSDGRVVVGEDGEKEPISFETAEVINVKGVQLNEIENVFQKVRKYKIAKATVRQWFNEFPIEQITLGIDHVLSEVKVGKEIKNIGGYINQMVKTSSLFEVAQEQKTEQERKRMQQQEKQQQEKTLNEQVNSLKIQAHNMRLEVLAELVQNQEIKQALIDKFSVGLFKTYYKPSLGFEENIKNPAVAGFMIATAGQLYPERFVEAEQLVKRAEALERGR
>CP030854.1|AXE21937.1|15726_16401_-|hypothetical-protein
MSRRTVAKYWNRIEFVPKASRKRSNILDFENYLQQRWQEGQQSAKALYEEISDKGFTYSQATVYNMVRKYPKSVLEPLPASVKATYYSSKQLSIWLGMYQNDWEDYMPIEFLRKLLEENPLIKAVREIALEFRQLMKAKQGNQLQDWCNKALDSGVEALKGFVRGVKQDFKAIFQAFTSEWSNGQVEGQVNRLKNIKRQMYGRASFELLRKRVIMMGIPDFHQM
>CP030854.1|AXE21971.1|16429_16792_-|hypothetical-protein
MLEHPSIAIVSRDRSNTYAAAITEACPQAEQIADRWHILKNLSETVERFLDTLRGEIKETALKLSQQQQQNSVNEEITADKSETPPIESQLQKPVFVGKYQDNMRVAAPFESQRITIEGI
>CP030854.1|AXE21938.1|16889_17393_-|hypothetical-protein
MDSSFLLPSELDLELLDYELYPDRIDLQVISTASSTCCPVCGHLSHKIHSCYHRIIHDLPASGRRVRLQLQVRKYFCKNTDCPRLIFTERFVTGLASYARRFDRLNQVLTGMGLESGGNPSTRQARYFSVKVSASTVLRLIKKCNMPSITAPKIIGVDDCRAAVAGV
>CP030854.1|AXE21939.1|20540_21113_-|CRISPR-associated-protein-Cas4
MTLTPSHIIEYLYCPRFTYFEYVLAIPQYEEKNYKVMRGRELHDLKLEQNKDYLRRRIGAVSKHIDQYLTNDIIRGRVDEVLGLSNGTMVPLDYKFAEYKDRVYETYRTQLYCYAWLIEENFGHKVEKGFLVYTRSRNKLIEVPITEENKQEVKDTAKAIGRIIEDNFFPKATKYKARCVGCTYRNMCIR
>CP030854.1|AXE21940.1|21112_21403_-|CRISPR-associated-endonuclease-Cas2
MIIWVLYDIEKDKSRTKVSKLCEQAGLYRVQYSCFLGTLTANEKDTLRLQIEALIDEEKDKVYIFPMSKDELRNTDLLGQAFDKDLVTDQIRALFF
>CP030854.1|AXE21941.1|21448_22438_-|CRISPR-associated-endonuclease-Cas1
MHLHINTYGTYVHVKDDMFEIRKKAENGELEKKHFSANKVEGIILATGSALSTDAIKLAMMHNVDILFIEQNGEPIGRVWHAKLGSTTKIRKRQLEASLDNVGVKWTKTWLLTKLDNQLNFIKDLKKHRPQHADFLNDKITRIEALSVSISSLEARKVSEIADTLRGLEGTAGRLYFETLSYVFPKEYAFNGRSSRPAKDAFNAFLNYAYGILYGKIEKALIVAGVDPYVGFMHRDDYNQLSMVFDFIEPYRAFADEVVFRLFSAKKVNKSHVDELQNGMSLNKTGKELLVLAFTKFMDDDPIKHKGCNLVRSHVIQADAHSFANALIA
>CP030854.1|AXE21942.1|22660_23326_-|DNA-repair-protein
MTLPLTTVTFPEIPLRTRDAHKLRGYFGDFFKEHSPLLHNHYEDGSLRYAYPLVQYKVLNRVPTLVGLGEGAQLLVELFLRIRALDIDGRKIEVLSKHIDHQQAAVEVGSALVKYRFETLWMPLNQENHREYLSADDKTRQELLQRILQNNILAFLKGAGAYQPDLPRLMLLLNVQAQTTTQFKNQTMLAFTGDFVVNATLPNGIGLGKSVARGFGSIVRQ
>CP030854.1|AXE21943.1|23337_25695_-|CRISPR-associated-helicase/endonuclease-Cas3
MKDNFLPHILAKSKPEDNPETLVQHTDKLIDAWSELRKRYDSVLNKDERFWFDSFIAIIFHDFGKLSQNFQEVLRKALKRKALYKLEPLRHEFLSGMLLAYHTVVEFRKCQDLQPNYSQLFAVLTHHKNFTTSLFDGDKFVKWTIHQADFEEFIEYAKARITEHFTNQGVYLQDISYAWRILSENQENLELQYSDKDDIVEETTFGFKNSGGYEHRFDYILHKSILVASDWSASGHRNLEEPLSYTHQNIFDKVKTRVGERFKGFRQFQNISSQTKGNVLAIAPTGSGKTEASLLWAADRHHDFQRIVYLLPTRVTANALYKRMDNYFGKASNGKDDYVAVVHSSAKLFRQELDEKYDDFSYLRESSFFKSVTVGTVDQMLTQGFNVGWWELKTFHLFRAKVIIDEVHAYAPYTLGLIISSIQYLRKNFQTEFYIMTATMPSQLRDLLTEALGGKENVTLIPDNELLNKKGRNEFRILDKSVTIDTLKPEIEERLKKGKKILLVANTVDEAIRLYDAYKGFDRLCYHSRYIVKHRTEKERLIEQYETDKEGEGFLLIATQVVEVSLDIDYDYLYTENAPIDAIIQRAGRINRKRDESKETEIIVFWHREVSEKIYEDAEIPLKVLETTYNKLRERVEQKKRLSEQDLIDLVEKVYCNWKIETHPSYQKGLKKHEEIIKNFCAYVMDFDEDKENVLTREGLDTVTIIPWCFKDMLKDANSKEKSKYEVSIQKKVYQIVRGKVKRFTDNDGFEYLNVPYSFKKGVSFSKKEIEALNPKGEDKLAFCF
>CP030854.1|AXE21944.1|25691_26399_-|CRISPR-associated-protein-Cas5
MLHCVIEIRSVTASFRNPEFQNFHKSFRLPPPTTLIGLAGAALGLSPKSAQDFFEKDSFRAGVRGIASGMARDLWKYDTLPGRSVITREILMDTHYWIVFGCESQETIHQIKAAFDNPVFALTMGSSDSLAKIVKTELIESESESNELENALVEDDIIPLVLAQALKGGEFSFGVNDSDPIAYQLPTRFAYESDYGVRKIAARKLFSFIGPKVTFKDEVFRGVHFGDVFIPTFTL

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Crispr_ID: CP030854_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030854_2

15262-15687

Unclear

Consensus_repeat	Method
ATTTCAATTCCACTGAGGTACGATTAAGGG	CRT
ATTTCAATTCCACTGAGGTACGATTAAGGG	PILER-CR
ATTTCAATTCCACTGAGGTACGATTAAG	CRISPRCasFinder

6 spacers

cas4,cas2,cas1,cas6,cas3,cas5,cas7

The CRISPR arrays of CP030854_2

>merge|CP030854|2|15262-15687|CRT,PILER-CR,CRISPRCasFinder
GATACAGACTTAAAGAGGTACGATTAAGGATCGGCCTGTAACATTGCTTGCAGAGTGTTACCGCTATTTCAATTCCACTGAGGTACGATTAAGGGACTATGGATGATTGGGCTAAGTTCATGCAGATGCGTTATTTCAATTCCACTGAGGTACGATTAAGGGCCGTTTCAGCACGTTTGTAGCCATCGGTGACATATCATTTCAATTCCACTGAGGTACGATTAAGGGTCAATCAGCTTATCTTCGGCGGCTGAATAGAACTGCGATTTCAATTCCACTGAGGTACGATTAAGGGTCAGAGGGCGGGGATTGATAGAGTTTTCTATTACATTTCAATTCCACTGAGGTACGATTAAGAGTGATAGACCGCAAAACGGGCGCTGAAGTAGGAGAAATATTTCAATTCCACTGAGGTACGATTAAGGG

>CP030854|2|1|15262-15687|CRT
GATACAGACTTAAAGAGGTACGATTAAGGA	TCGGCCTGTAACATTGCTTGCAGAGTGTTACCGCT
ATTTCAATTCCACTGAGGTACGATTAAGGG	ACTATGGATGATTGGGCTAAGTTCATGCAGATGCGTT
ATTTCAATTCCACTGAGGTACGATTAAGGG	CCGTTTCAGCACGTTTGTAGCCATCGGTGACATATC
ATTTCAATTCCACTGAGGTACGATTAAGGG	TCAATCAGCTTATCTTCGGCGGCTGAATAGAACTGCG
ATTTCAATTCCACTGAGGTACGATTAAGGG	TCAGAGGGCGGGGATTGATAGAGTTTTCTATTAC
ATTTCAATTCCACTGAGGTACGATTAAGAG	TGATAGACCGCAAAACGGGCGCTGAAGTAGGAGAAAT
ATTTCAATTCCACTGAGGTACGATTAAGGG

>CP030854|2|2|15327-15687|PILER-CR
ATTTCAATTCCACTGAGGTACGATTAAGGG	ACTATGGATGATTGGGCTAAGTTCATGCAGATGCGTT
ATTTCAATTCCACTGAGGTACGATTAAGGG	CCGTTTCAGCACGTTTGTAGCCATCGGTGACATATC
ATTTCAATTCCACTGAGGTACGATTAAGGG	TCAATCAGCTTATCTTCGGCGGCTGAATAGAACTGCG
ATTTCAATTCCACTGAGGTACGATTAAGGG	TCAGAGGGCGGGGATTGATAGAGTTTTCTATTAC
ATTTCAATTCCACTGAGGTACGATTAAGAG	TGATAGACCGCAAAACGGGCGCTGAAGTAGGAGAAAT
ATTTCAATTCCACTGAGGTACGATTAAGGG

>CP030854|2|1|15327-15685|CRISPRCasFinder
ATTTCAATTCCACTGAGGTACGATTAAG	GGACTATGGATGATTGGGCTAAGTTCATGCAGATGCGTT
ATTTCAATTCCACTGAGGTACGATTAAG	GGCCGTTTCAGCACGTTTGTAGCCATCGGTGACATATC
ATTTCAATTCCACTGAGGTACGATTAAG	GGTCAATCAGCTTATCTTCGGCGGCTGAATAGAACTGCG
ATTTCAATTCCACTGAGGTACGATTAAG	GGTCAGAGGGCGGGGATTGATAGAGTTTTCTATTAC
ATTTCAATTCCACTGAGGTACGATTAAG	AGTGATAGACCGCAAAACGGGCGCTGAAGTAGGAGAAAT
ATTTCAATTCCACTGAGGTACGATTAAG

Protein	Signature genes	Signature genes Name	Protein_function
CP030854.1\|AXE21941.1\|21448_22438_-\|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187766
CP030854.1\|AXE21937.1\|15726_16401_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225995
CP030854.1\|AXE21971.1\|16429_16792_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376574
CP030854.1\|AXE21930.1\|1999_2932_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184751
CP030854.1\|AXE21938.1\|16889_17393_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225995
CP030854.1\|AXE21944.1\|25691_26399_-\|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	gnl\|CDD\|273860
CP030854.1\|AXE21940.1\|21112_21403_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
CP030854.1\|AXE21943.1\|23337_25695_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
CP030854.1\|AXE21934.1\|10123_10441_-\|hypothetical-protein	unknown	unknown	unknown
CP030854.1\|AXE21970.1\|8630_9464_-\|hypothetical-protein	unknown	unknown	unknown
CP030854.1\|AXE21932.1\|3699_5232_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|185760
CP030854.1\|AXE21939.1\|20540_21113_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768
CP030854.1\|AXE21942.1\|22660_23326_-\|DNA-repair-protein	cas6	cls000004_cas6_CAS-I:CAS-III	gnl\|CDD\|380073
CP030854.1\|AXE21945.1\|26411_27296_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
CP030854.1\|AXE21936.1\|12115_13573_+\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
CP030854.1\|AXE21935.1\|10495_11155_-\|chromosome-partitioning-protein-ParA	unknown	unknown	gnl\|CDD\|222854
CP030854.1\|AXE21931.1\|3274_3565_+\|hypothetical-protein	unknown	unknown	unknown
CP030854.1\|AXE21933.1\|5260_8569_-\|SusC/RagA-family-protein	unknown	unknown	gnl\|CDD\|274948

Protein	Function_ID	Function_description	E-value
CP030854.1\|AXE21941.1\|21448_22438_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.51346e-89
CP030854.1\|AXE21937.1\|15726_16401_-\|hypothetical-protein	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.94495e-19
CP030854.1\|AXE21932.1\|3699_5232_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	5.5718e-45
CP030854.1\|AXE21930.1\|1999_2932_-\|hypothetical-protein	gnl\|CDD\|184751	PRK14571, PRK14571, D-alanyl-alanine synthetase A; Provisional.	2.52645e-24
CP030854.1\|AXE21938.1\|16889_17393_-\|hypothetical-protein	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.33527e-10
CP030854.1\|AXE21944.1\|25691_26399_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	1.6617e-12
CP030854.1\|AXE21940.1\|21112_21403_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.68386e-20
CP030854.1\|AXE21943.1\|23337_25695_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	2.00663e-63
CP030854.1\|AXE21971.1\|16429_16792_-\|hypothetical-protein	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	3.65157e-06
CP030854.1\|AXE21939.1\|20540_21113_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	8.46678e-25
CP030854.1\|AXE21942.1\|22660_23326_-\|DNA-repair-protein	gnl\|CDD\|380073	pfam17955, Cas6b_N, Cas6b N-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. Four Cas proteins (Cas5, Cas6b, Cas7 and Cas8b) are proposed to form a Type I-B Cascade complex that mediates the antiviral defense. This is the N-terminal domain found in Cas6b proteins. Cas6b is a member of Cas6 RNA processing endoribonucleases found in bacteria and archaea whose RNA substrates have a wide range of structural features. Cocrystal structures of Cas6 from Methanococcus maripaludis (MmCas6b) bound with its repeat RNA revealed a dual-site binding structure and a cleavage site conformation poised for phosphodiester bond breakage.	9.82647e-39
CP030854.1\|AXE21945.1\|26411_27296_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	1.12971e-66
CP030854.1\|AXE21936.1\|12115_13573_+\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	2.9345e-31
CP030854.1\|AXE21935.1\|10495_11155_-\|chromosome-partitioning-protein-ParA	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	4.06571e-43
CP030854.1\|AXE21933.1\|5260_8569_-\|SusC/RagA-family-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0

>CP030854.1|AXE21936.1|12115_13573_+|replication-initiation-protein
MAKKELPKRRKQDLQERYTIRIQGGKSGLVEATSKMDIHEFRVFATMLTMVLPEDEDFTTYELRVQDIIKLFSLKKDGRYYELVRDAAHKLLDRKFVIYEMKNGEEYKTTINLITETSEPVSEINKNHILLQFSPKLKPYLLQLKKEYLTIDIRNIQDISSPYSVKLYMVLKHQQRLGNYKVKYPIERLRQILAIEEGEYGLYGSFKQQVIRRTLSDIEKYTDLSVLKIEEEKAGRSVSAIIFHVVEKEAQRQNEIKIKKQQHNILKKSDGRVVVGEDGEKEPISFETAEVINVKGVQLNEIENVFQKVRKYKIAKATVRQWFNEFPIEQITLGIDHVLSEVKVGKEIKNIGGYINQMVKTSSLFEVAQEQKTEQERKRMQQQEKQQQEKTLNEQVNSLKIQAHNMRLEVLAELVQNQEIKQALIDKFSVGLFKTYYKPSLGFEENIKNPAVAGFMIATAGQLYPERFVEAEQLVKRAEALERGR
>CP030854.1|AXE21935.1|10495_11155_-|chromosome-partitioning-protein-ParA
MIITVGGIKGGSGKTTVATNLAIYISQRGGDVLLVDADDQETATDFTAWREETKMGEVGYTAVKLTGDQVRTQVAKLKSKYQYVVIDTGGRDTTSQRAALFISDIYLLPFNPRSFDVWTVGKVEKLIMEIRAVRPAELLAFSFINRADARGSDNNDAAELLAQSEVMEYLEMPLGNRKAFSHAAAKGLGVTELLPVDEKAVNELTSLFNKVLSHTNALI
>CP030854.1|AXE21934.1|10123_10441_-|hypothetical-protein
MAVSAPPKKKVPETPPVVSEEEITKVINKGGSPVNKLAKTRTRDKTKPIRAIAVSLTSEEIDSIISLRNQRPSPSRTKKIPISLHDWILEAVQEKIERERKKYQM
>CP030854.1|AXE21970.1|8630_9464_-|hypothetical-protein
MAVLFLGTADMEVKIVASTTIDSLGACQGVSYLLGKVYLYGDREVGMIRTYALNSNQLIYTGQEIKLTQNGQDVINHPTGIAHNGSKHTFVGNSIRLNPEGTQWKAVIYAVDWEGLQRTKTLDGNLLNVIEDDICIQGTRPEYVQYEGKWYVATADYGPKSNEVRLYDPQILSKAKKTSEAGVLFKKFSCSAWVQNLHWIPSKGILVLIQNQIEGRKWRFTFIDLKKSVASGQQQVLNVVDIDKSDELEGFTLLEGSSTGMAVTSSRHQNVHLVTVK
>CP030854.1|AXE21933.1|5260_8569_-|SusC/RagA-family-protein
MNIYKTPTKSWMCFCILFLGLTFLHQFPASATKLQQAIKVTGIITDEANQPLPGVSIVEKQTRKGTVSDEQGKFSLDVSTEAVLVISSVGFVPQEVVINGQTSLTIKLKEDINMLNEVVAVGYQILRKSDVTGAISNVKARELNLAAPTLGQALVGKLAGVQVSQVSGAPYVSTKIRVRGIGSINASSDPLYVIDGFPAGNDVFINPNDIESIDILKDAASAAIYGSRASGGVVIITTKRGKEGNGKMEYDYQYGVHQLAKKVKLLNSEQFAQLLIDARNNTYRDLYENSGKTWNNSMYSDDNATRVSKVGNASAVSIPTDIYDFANQKLIAPKYNTDWQNELYRNAPVSRHNLTFSGGNKGGRYLVSLGYQNQQGIIVATKQERLNFRVNVDGDLTEKLKVGASIFVTSTNGREVQEGRFNQGVVLGALIYPPTFRAYDDNGVLLKNQVAAQQPTFGYQTVENPVALALETNINRRGLRANYNGNLTYELLPGLSAKANIGLQTYNEKYEYYLPTSLSSGNNPPYSTQSYAAARATAQTLATTNLLGEFTANYTKQFGEHGINLLAGYTAQKYNSDLISVSAQGFQNDLIQEITAKGADPANFFLNGGTGKVEETLLSYLARAEYRFASRYYITAAFRRDGSSRFGPLNRWGAFPSVSAGWNISEESFYNNMLGEASTLKLRASWGLTGNYNIGNYNYLQTMANPSGTVFGNGTINTAVWAGPIKDQRLGWESTSQYNVGLDVGLLRNRLSFIFNAYLSNSYNLLFNQPVSAISGTSTILTNLRDSKVQNKGVELQIDGRLVSTKEFKLNLSGNISFNRNKVLNMGGANTIITNGAERSYLTHITQEGQPIGMFYGFKVIGMVREKDMENIAVDNANYNASKQSFPAGYVLKGPARSTASSNPLRPGDLIFEDVNKDGVVNDADKQVIGTPYPKFTYGFSLNASYRDFDLGAAFNGVYGNQVLDGQDYYVYNMEASGNQYVDVINRYRSEAEPGNGLVYRAARGGTQSNSTRLSTFYLQSGSFFRCTNLSLGYNLPTKWLGKWKVEGLRVYANVNNAFTMTKYKGYNPEVDYNGGANLTPGVDYGMYPLARAYNIGAKLTF
>CP030854.1|AXE21932.1|3699_5232_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTIRNSILCLCLTLGAMSCNDNFLVETDPNSVATSNYFKNENDVLLAVNGAYQALRNNNGLAEGSMLYSEERSDNTGRNDNQSNAGEPFQFNDFSLLPSNTYLKTHWLALYQIITRTNLVLDGIEKVTFSNATTKAQYQAEAKFIRALVYFHLVRKWGDVPLVIKPLSSSDEVKANTAREKKDKVYAQIVADLTDVVNSSLPDHQPVANKGRVSKVAGMALLGQVYLTMATTLDAANRTTNLNQAKTYLTGAYEKRTFGLLKEIAYTDVFDVAKKSTNPEIIFQIVYKQGDINYASNIAVSTQAQGENINSLRTTTGTGGNVTPDLVKEYEEGDLRKDFSIKYANAANVKDYFITKYRDVSAAAGANGYGGNDWILMRYADVILMLAEVNLYLGNDAAAIGFLNQVRERAKMPLYEVAKEAPAYKAKFPTLKMAILHERRIELAFENHRWFDLLRFFTPAELVTYMGTKLQADFGAAKISNFGLKDYYYPIPFDEFKLDPVKMYQNEGY
>CP030854.1|AXE21931.1|3274_3565_+|hypothetical-protein
MKSKIKAQASEIAKKIADVMIEEATSKKIKKAVNKTSEKLAKRIVKIKQKEAKEKDKVEKKAEKKVLKAAKKVSQEKKVKKVAKVSKKNEDATPIA
>CP030854.1|AXE21930.1|1999_2932_-|hypothetical-protein
MKLLYLYSDSDFTPWRENINAATIASLIQATPDNVQTFVTHFVGFTAEFADFLRQFDLIFNVCYGYGVADQVEVVRWLDWHGIKHTASSYSTQLLAMDKALLPDMCMQVGVNTPRILLPNELFEFSSTTTFIAKHRYGSLHRNMLFFKKDNIPSQQLNSLESYIIQPYIEGREFTVAVIPDKNGLNPECLPPLEIIPNDGRAIYVAGQNYGPTYKDFQPQLDEHLYDMMTEGVLELHKLLEIKGMSRTDIRIANDEVYILDINTMPNLDPQRSYLPALANHHRIQLRELIERTIKSALIWYERQLVQQPD
>CP030854.1|AXE21937.1|15726_16401_-|hypothetical-protein
MSRRTVAKYWNRIEFVPKASRKRSNILDFENYLQQRWQEGQQSAKALYEEISDKGFTYSQATVYNMVRKYPKSVLEPLPASVKATYYSSKQLSIWLGMYQNDWEDYMPIEFLRKLLEENPLIKAVREIALEFRQLMKAKQGNQLQDWCNKALDSGVEALKGFVRGVKQDFKAIFQAFTSEWSNGQVEGQVNRLKNIKRQMYGRASFELLRKRVIMMGIPDFHQM
>CP030854.1|AXE21971.1|16429_16792_-|hypothetical-protein
MLEHPSIAIVSRDRSNTYAAAITEACPQAEQIADRWHILKNLSETVERFLDTLRGEIKETALKLSQQQQQNSVNEEITADKSETPPIESQLQKPVFVGKYQDNMRVAAPFESQRITIEGI
>CP030854.1|AXE21938.1|16889_17393_-|hypothetical-protein
MDSSFLLPSELDLELLDYELYPDRIDLQVISTASSTCCPVCGHLSHKIHSCYHRIIHDLPASGRRVRLQLQVRKYFCKNTDCPRLIFTERFVTGLASYARRFDRLNQVLTGMGLESGGNPSTRQARYFSVKVSASTVLRLIKKCNMPSITAPKIIGVDDCRAAVAGV
>CP030854.1|AXE21939.1|20540_21113_-|CRISPR-associated-protein-Cas4
MTLTPSHIIEYLYCPRFTYFEYVLAIPQYEEKNYKVMRGRELHDLKLEQNKDYLRRRIGAVSKHIDQYLTNDIIRGRVDEVLGLSNGTMVPLDYKFAEYKDRVYETYRTQLYCYAWLIEENFGHKVEKGFLVYTRSRNKLIEVPITEENKQEVKDTAKAIGRIIEDNFFPKATKYKARCVGCTYRNMCIR
>CP030854.1|AXE21940.1|21112_21403_-|CRISPR-associated-endonuclease-Cas2
MIIWVLYDIEKDKSRTKVSKLCEQAGLYRVQYSCFLGTLTANEKDTLRLQIEALIDEEKDKVYIFPMSKDELRNTDLLGQAFDKDLVTDQIRALFF
>CP030854.1|AXE21941.1|21448_22438_-|CRISPR-associated-endonuclease-Cas1
MHLHINTYGTYVHVKDDMFEIRKKAENGELEKKHFSANKVEGIILATGSALSTDAIKLAMMHNVDILFIEQNGEPIGRVWHAKLGSTTKIRKRQLEASLDNVGVKWTKTWLLTKLDNQLNFIKDLKKHRPQHADFLNDKITRIEALSVSISSLEARKVSEIADTLRGLEGTAGRLYFETLSYVFPKEYAFNGRSSRPAKDAFNAFLNYAYGILYGKIEKALIVAGVDPYVGFMHRDDYNQLSMVFDFIEPYRAFADEVVFRLFSAKKVNKSHVDELQNGMSLNKTGKELLVLAFTKFMDDDPIKHKGCNLVRSHVIQADAHSFANALIA
>CP030854.1|AXE21942.1|22660_23326_-|DNA-repair-protein
MTLPLTTVTFPEIPLRTRDAHKLRGYFGDFFKEHSPLLHNHYEDGSLRYAYPLVQYKVLNRVPTLVGLGEGAQLLVELFLRIRALDIDGRKIEVLSKHIDHQQAAVEVGSALVKYRFETLWMPLNQENHREYLSADDKTRQELLQRILQNNILAFLKGAGAYQPDLPRLMLLLNVQAQTTTQFKNQTMLAFTGDFVVNATLPNGIGLGKSVARGFGSIVRQ
>CP030854.1|AXE21943.1|23337_25695_-|CRISPR-associated-helicase/endonuclease-Cas3
MKDNFLPHILAKSKPEDNPETLVQHTDKLIDAWSELRKRYDSVLNKDERFWFDSFIAIIFHDFGKLSQNFQEVLRKALKRKALYKLEPLRHEFLSGMLLAYHTVVEFRKCQDLQPNYSQLFAVLTHHKNFTTSLFDGDKFVKWTIHQADFEEFIEYAKARITEHFTNQGVYLQDISYAWRILSENQENLELQYSDKDDIVEETTFGFKNSGGYEHRFDYILHKSILVASDWSASGHRNLEEPLSYTHQNIFDKVKTRVGERFKGFRQFQNISSQTKGNVLAIAPTGSGKTEASLLWAADRHHDFQRIVYLLPTRVTANALYKRMDNYFGKASNGKDDYVAVVHSSAKLFRQELDEKYDDFSYLRESSFFKSVTVGTVDQMLTQGFNVGWWELKTFHLFRAKVIIDEVHAYAPYTLGLIISSIQYLRKNFQTEFYIMTATMPSQLRDLLTEALGGKENVTLIPDNELLNKKGRNEFRILDKSVTIDTLKPEIEERLKKGKKILLVANTVDEAIRLYDAYKGFDRLCYHSRYIVKHRTEKERLIEQYETDKEGEGFLLIATQVVEVSLDIDYDYLYTENAPIDAIIQRAGRINRKRDESKETEIIVFWHREVSEKIYEDAEIPLKVLETTYNKLRERVEQKKRLSEQDLIDLVEKVYCNWKIETHPSYQKGLKKHEEIIKNFCAYVMDFDEDKENVLTREGLDTVTIIPWCFKDMLKDANSKEKSKYEVSIQKKVYQIVRGKVKRFTDNDGFEYLNVPYSFKKGVSFSKKEIEALNPKGEDKLAFCF
>CP030854.1|AXE21944.1|25691_26399_-|CRISPR-associated-protein-Cas5
MLHCVIEIRSVTASFRNPEFQNFHKSFRLPPPTTLIGLAGAALGLSPKSAQDFFEKDSFRAGVRGIASGMARDLWKYDTLPGRSVITREILMDTHYWIVFGCESQETIHQIKAAFDNPVFALTMGSSDSLAKIVKTELIESESESNELENALVEDDIIPLVLAQALKGGEFSFGVNDSDPIAYQLPTRFAYESDYGVRKIAARKLFSFIGPKVTFKDEVFRGVHFGDVFIPTFTL
>CP030854.1|AXE21945.1|26411_27296_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKTNSLTITYLAKVSFASLNGGDKEVDNINTIKKVTLENGDQLPYMSAQAVRRALRDKLQELGWSVSPVGESSEDKGAAKTAGEGGKFIDDDLFGFMDAAKAGTFVRTSPVRVEALLALNKFQEDLDFGTNYMAKDSGGNPNIFETEIHSGIYRGTILIELDRVGEELKGAGKKEFSITNEDKATRVNALIDAFQMLWSSGRQSRFLADISPKFVAAALMKSKNPIFLETLKIKRDGQVDIEALKSVTNDYAPFIDQSVFATQEGVFTKNDDTVVSLGEGFATMKGWVNSYYGV

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Crispr_ID: CP030854_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP030854_3

17500-20334

Unclear

I-B

Consensus_repeat	Method
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	PILER-CR
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CRISPRCasFinder
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CRT

38 spacers

cas4,cas2,cas1,cas6,cas3,cas5,cas7,cas8b8,WYL

The CRISPR arrays of CP030854_3

>merge|CP030854|3|17500-20334|PILER-CR,CRISPRCasFinder,CRT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTGAAGATTGCGAGCAAGCTGGCCGAATTGAAAAACTAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGCTATTCGGGCACTAACCCCTTGCCCGTGTACATTAGGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGACATAGACGCTAATTGTCGGGTTAGGTTACCCGGCTTGCTGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGACGCGGCAAAAAGTAGAAATACCCGCCCAAAGAACCAAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTCCGGGACGATTTAAGAAGGCGCAAGTCTCTTGGAAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGCTGCTACTGCACAAGTGAACAAAAGCCCACCAAGCAGGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGAATTTGGAATAAGCATTTAGATAGCTTGGATTATGTGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGCAAGGCGTTTGCATAGGCTGAACCATCCGCAAGGGTGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTATTTTTATTTCTTGCCCTTGCTCCATGTGTGGATAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGCCAACAACGCCAACCCCAACAACGGCAAACGAGTTTGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGGTTGCGTTTCCGTTTCTGGTGGGCCTGATTCACTACCGGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGACTAAGAAAGATATTTGAAGTGTTGGGCGAACCATGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTTTTTCAAAAGACCTCTATCAACTCCCATTTTAAAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGGTTGATTGGTGAGCATTGCCAACGCCTGATTTCCCTGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGATTTGAGGCGATTATCAAGTATTACGAGCTAGTGCGGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGAGCGGCGAGGATTGTAAGGTTAAAATCAGAAACCACGGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGCAAAAGCAGATGTAGTCAATTTGCTTAGTAACAGGCGGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGGCGGCTCTTTTTATCATTGAGCGTATCAGGAAGTAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGGTACTTTTCAGGCTACGATTTTAGGCACGATGTCGGAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTTGGAAATTTGAAGTTTGAACACGCTTGGGTCAATGCGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGGGGAACCTTAATTTTTACAAGTTCAGAACGGAAAACCGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTACAAAAGCAGGGTATTTTCAAGCCGTTCAATCGTAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGCTGGTCATCAGTAAGGCCCACATTTTCCTTAATTGTATGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGATCGCTACGGGAGAAGATAGAGTTGCAACCAATGCCGGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGATGTTCTGAAATACGTACGATCATACATCAACCATGCCAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGCTGAGGGCTTTCATATCTTTTATGCGTCCGTACCCTTGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGAGACCTGTCGCGGCTAAGAATCATTTCTGGGAAAACGTGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTCCAATCTACTGCCCCGTTGTTCCATGTCAGCTTAGGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGCTTCAAATTTTCAGTTGAGAACCGCTACAGGATGGGGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTCTACCTTGAAACATTTTATTGATTTTTATAGGGTTGAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGAAGTCCTGAAGAACCAACCCCCATACAATATCAGCGTGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGGTATTTGTTGCGGTACCATCAACGGTAAATCTGACAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTTACAACGCAAACCGGGCCGCTTTTGACAAGACCAAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTTGGCGTACAAAAAAAAGCCCTCGTGCTGAGGGCTAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGTTGAGCGTTCTTTAGTGCCTGAAAACTTTGATTTAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGATAAGCCCGATGTGGGCAAGCAGGTGGATGAATGGAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGCTATTCTCGGCCTTTTTACCCGAAACTTTTTCCTGAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAGATTGTCTGAGCATAGCCCGTTGCAGACGTCTGCTCTAGTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG

>CP030854|3|3|17500-20334|PILER-CR
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TGAAGATTGCGAGCAAGCTGGCCGAATTGAAAAACTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTATTCGGGCACTAACCCCTTGCCCGTGTACATTAG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ACATAGACGCTAATTGTCGGGTTAGGTTACCCGGCTTGCT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ACGCGGCAAAAAGTAGAAATACCCGCCCAAAGAACCAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TCCGGGACGATTTAAGAAGGCGCAAGTCTCTTGGAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTGCTACTGCACAAGTGAACAAAAGCCCACCAAGCAG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AATTTGGAATAAGCATTTAGATAGCTTGGATTATGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CAAGGCGTTTGCATAGGCTGAACCATCCGCAAGGGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TATTTTTATTTCTTGCCCTTGCTCCATGTGTGGATA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CCAACAACGCCAACCCCAACAACGGCAAACGAGTTT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTTGCGTTTCCGTTTCTGGTGGGCCTGATTCACTACCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ACTAAGAAAGATATTTGAAGTGTTGGGCGAACCAT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTTTTCAAAAGACCTCTATCAACTCCCATTTTAAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTTGATTGGTGAGCATTGCCAACGCCTGATTTCCCT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATTTGAGGCGATTATCAAGTATTACGAGCTAGTGCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AGCGGCGAGGATTGTAAGGTTAAAATCAGAAACCACG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CAAAAGCAGATGTAGTCAATTTGCTTAGTAACAGGCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GCGGCTCTTTTTATCATTGAGCGTATCAGGAAGTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTACTTTTCAGGCTACGATTTTAGGCACGATGTCGGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTGGAAATTTGAAGTTTGAACACGCTTGGGTCAATGC
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GGGAACCTTAATTTTTACAAGTTCAGAACGGAAAACC
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TACAAAAGCAGGGTATTTTCAAGCCGTTCAATCGTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTGGTCATCAGTAAGGCCCACATTTTCCTTAATTGTAT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATCGCTACGGGAGAAGATAGAGTTGCAACCAATGCCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATGTTCTGAAATACGTACGATCATACATCAACCATGCCA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTGAGGGCTTTCATATCTTTTATGCGTCCGTACCCTT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AGACCTGTCGCGGCTAAGAATCATTTCTGGGAAAACGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TCCAATCTACTGCCCCGTTGTTCCATGTCAGCTTAG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTTCAAATTTTCAGTTGAGAACCGCTACAGGATGGG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TCTACCTTGAAACATTTTATTGATTTTTATAGGGTTGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AAGTCCTGAAGAACCAACCCCCATACAATATCAGCGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTATTTGTTGCGGTACCATCAACGGTAAATCTGACA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTACAACGCAAACCGGGCCGCTTTTGACAAGACCAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTGGCGTACAAAAAAAAGCCCTCGTGCTGAGGGCTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTGAGCGTTCTTTAGTGCCTGAAAACTTTGATTTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATAAGCCCGATGTGGGCAAGCAGGTGGATGAATGGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTATTCTCGGCCTTTTTACCCGAAACTTTTTCCTGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATTGTCTGAGCATAGCCCGTTGCAGACGTCTGCTCTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG

>CP030854|3|2|17500-20334|CRISPRCasFinder
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TGAAGATTGCGAGCAAGCTGGCCGAATTGAAAAACTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTATTCGGGCACTAACCCCTTGCCCGTGTACATTAG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ACATAGACGCTAATTGTCGGGTTAGGTTACCCGGCTTGCT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ACGCGGCAAAAAGTAGAAATACCCGCCCAAAGAACCAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TCCGGGACGATTTAAGAAGGCGCAAGTCTCTTGGAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTGCTACTGCACAAGTGAACAAAAGCCCACCAAGCAG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AATTTGGAATAAGCATTTAGATAGCTTGGATTATGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CAAGGCGTTTGCATAGGCTGAACCATCCGCAAGGGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TATTTTTATTTCTTGCCCTTGCTCCATGTGTGGATA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CCAACAACGCCAACCCCAACAACGGCAAACGAGTTT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTTGCGTTTCCGTTTCTGGTGGGCCTGATTCACTACCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ACTAAGAAAGATATTTGAAGTGTTGGGCGAACCAT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTTTTCAAAAGACCTCTATCAACTCCCATTTTAAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTTGATTGGTGAGCATTGCCAACGCCTGATTTCCCT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATTTGAGGCGATTATCAAGTATTACGAGCTAGTGCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AGCGGCGAGGATTGTAAGGTTAAAATCAGAAACCACG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CAAAAGCAGATGTAGTCAATTTGCTTAGTAACAGGCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GCGGCTCTTTTTATCATTGAGCGTATCAGGAAGTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTACTTTTCAGGCTACGATTTTAGGCACGATGTCGGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTGGAAATTTGAAGTTTGAACACGCTTGGGTCAATGC
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GGGAACCTTAATTTTTACAAGTTCAGAACGGAAAACC
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TACAAAAGCAGGGTATTTTCAAGCCGTTCAATCGTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTGGTCATCAGTAAGGCCCACATTTTCCTTAATTGTAT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATCGCTACGGGAGAAGATAGAGTTGCAACCAATGCCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATGTTCTGAAATACGTACGATCATACATCAACCATGCCA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTGAGGGCTTTCATATCTTTTATGCGTCCGTACCCTT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AGACCTGTCGCGGCTAAGAATCATTTCTGGGAAAACGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TCCAATCTACTGCCCCGTTGTTCCATGTCAGCTTAG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTTCAAATTTTCAGTTGAGAACCGCTACAGGATGGG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TCTACCTTGAAACATTTTATTGATTTTTATAGGGTTGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AAGTCCTGAAGAACCAACCCCCATACAATATCAGCGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTATTTGTTGCGGTACCATCAACGGTAAATCTGACA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTACAACGCAAACCGGGCCGCTTTTGACAAGACCAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTGGCGTACAAAAAAAAGCCCTCGTGCTGAGGGCTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTGAGCGTTCTTTAGTGCCTGAAAACTTTGATTTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATAAGCCCGATGTGGGCAAGCAGGTGGATGAATGGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTATTCTCGGCCTTTTTACCCGAAACTTTTTCCTGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATTGTCTGAGCATAGCCCGTTGCAGACGTCTGCTCTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG

>CP030854|3|2|17500-20334|CRT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TGAAGATTGCGAGCAAGCTGGCCGAATTGAAAAACTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTATTCGGGCACTAACCCCTTGCCCGTGTACATTAG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ACATAGACGCTAATTGTCGGGTTAGGTTACCCGGCTTGCT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ACGCGGCAAAAAGTAGAAATACCCGCCCAAAGAACCAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TCCGGGACGATTTAAGAAGGCGCAAGTCTCTTGGAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTGCTACTGCACAAGTGAACAAAAGCCCACCAAGCAG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AATTTGGAATAAGCATTTAGATAGCTTGGATTATGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CAAGGCGTTTGCATAGGCTGAACCATCCGCAAGGGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TATTTTTATTTCTTGCCCTTGCTCCATGTGTGGATA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CCAACAACGCCAACCCCAACAACGGCAAACGAGTTT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTTGCGTTTCCGTTTCTGGTGGGCCTGATTCACTACCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ACTAAGAAAGATATTTGAAGTGTTGGGCGAACCAT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTTTTCAAAAGACCTCTATCAACTCCCATTTTAAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTTGATTGGTGAGCATTGCCAACGCCTGATTTCCCT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATTTGAGGCGATTATCAAGTATTACGAGCTAGTGCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AGCGGCGAGGATTGTAAGGTTAAAATCAGAAACCACG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CAAAAGCAGATGTAGTCAATTTGCTTAGTAACAGGCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GCGGCTCTTTTTATCATTGAGCGTATCAGGAAGTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTACTTTTCAGGCTACGATTTTAGGCACGATGTCGGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTGGAAATTTGAAGTTTGAACACGCTTGGGTCAATGC
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GGGAACCTTAATTTTTACAAGTTCAGAACGGAAAACC
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TACAAAAGCAGGGTATTTTCAAGCCGTTCAATCGTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTGGTCATCAGTAAGGCCCACATTTTCCTTAATTGTAT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATCGCTACGGGAGAAGATAGAGTTGCAACCAATGCCG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATGTTCTGAAATACGTACGATCATACATCAACCATGCCA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTGAGGGCTTTCATATCTTTTATGCGTCCGTACCCTT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AGACCTGTCGCGGCTAAGAATCATTTCTGGGAAAACGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TCCAATCTACTGCCCCGTTGTTCCATGTCAGCTTAG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTTCAAATTTTCAGTTGAGAACCGCTACAGGATGGG
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TCTACCTTGAAACATTTTATTGATTTTTATAGGGTTGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	AAGTCCTGAAGAACCAACCCCCATACAATATCAGCGT
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	GTATTTGTTGCGGTACCATCAACGGTAAATCTGACA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTACAACGCAAACCGGGCCGCTTTTGACAAGACCAA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTGGCGTACAAAAAAAAGCCCTCGTGCTGAGGGCTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	TTGAGCGTTCTTTAGTGCCTGAAAACTTTGATTTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATAAGCCCGATGTGGGCAAGCAGGTGGATGAATGGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	CTATTCTCGGCCTTTTTACCCGAAACTTTTTCCTGA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG	ATTGTCTGAGCATAGCCCGTTGCAGACGTCTGCTCTA
GTTTCAATCCTTATTCTGCTGGAATGTGCTCTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
CP030854.1\|AXE21941.1\|21448_22438_-\|CRISPR-associated-endonuclease-Cas1	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187766
CP030854.1\|AXE21947.1\|31057_31966_-\|transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
CP030854.1\|AXE21937.1\|15726_16401_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225995
CP030854.1\|AXE21932.1\|3699_5232_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	unknown	unknown	gnl\|CDD\|185760
CP030854.1\|AXE21938.1\|16889_17393_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225995
CP030854.1\|AXE21946.1\|29781_30966_-\|ATPase	unknown	unknown	gnl\|CDD\|224292
CP030854.1\|AXE21944.1\|25691_26399_-\|CRISPR-associated-protein-Cas5	cas5	cd09693_cas5_CAS-I	gnl\|CDD\|273860
CP030854.1\|AXE21940.1\|21112_21403_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
CP030854.1\|AXE21943.1\|23337_25695_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
CP030854.1\|AXE21934.1\|10123_10441_-\|hypothetical-protein	unknown	unknown	unknown
CP030854.1\|AXE21970.1\|8630_9464_-\|hypothetical-protein	unknown	unknown	unknown
CP030854.1\|AXE21971.1\|16429_16792_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376574
CP030854.1\|AXE21939.1\|20540_21113_-\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|187768
CP030854.1\|AXE21972.1\|27292_29059_-\|hypothetical-protein	cas8b8	cls000685_cas8b8_CAS-I-B	unknown
CP030854.1\|AXE21942.1\|22660_23326_-\|DNA-repair-protein	cas6	cls000004_cas6_CAS-I:CAS-III	gnl\|CDD\|380073
CP030854.1\|AXE21945.1\|26411_27296_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
CP030854.1\|AXE21936.1\|12115_13573_+\|replication-initiation-protein	unknown	unknown	gnl\|CDD\|376444
CP030854.1\|AXE21935.1\|10495_11155_-\|chromosome-partitioning-protein-ParA	unknown	unknown	gnl\|CDD\|222854
CP030854.1\|AXE21931.1\|3274_3565_+\|hypothetical-protein	unknown	unknown	unknown
CP030854.1\|AXE21933.1\|5260_8569_-\|SusC/RagA-family-protein	unknown	unknown	gnl\|CDD\|274948

Protein	Function_ID	Function_description	E-value
CP030854.1\|AXE21941.1\|21448_22438_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	2.51346e-89
CP030854.1\|AXE21947.1\|31057_31966_-\|transcriptional-regulator	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	4.20039e-14
CP030854.1\|AXE21937.1\|15726_16401_-\|hypothetical-protein	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	7.94495e-19
CP030854.1\|AXE21971.1\|16429_16792_-\|hypothetical-protein	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	3.65157e-06
CP030854.1\|AXE21938.1\|16889_17393_-\|hypothetical-protein	gnl\|CDD\|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.33527e-10
CP030854.1\|AXE21944.1\|25691_26399_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	1.6617e-12
CP030854.1\|AXE21940.1\|21112_21403_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.68386e-20
CP030854.1\|AXE21943.1\|23337_25695_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	2.00663e-63
CP030854.1\|AXE21946.1\|29781_30966_-\|ATPase	gnl\|CDD\|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	1.59182e-50
CP030854.1\|AXE21932.1\|3699_5232_-\|RagB/SusD-family-nutrient-uptake-outer-membrane-protein	gnl\|CDD\|185760	cd08977, SusD, starch binding outer membrane protein SusD. SusD-like proteins from Bacteroidetes, members of the human distal gut microbiota, are part of the starch utilization system (Sus). Sus is one of the large clusters of glycosyl hydrolases, called polysaccharide utilization loci (PULs), which play an important role in polysaccharide recognition and uptake, and it is needed for growth on amylose, amylopectin, pullulan, and maltooligosaccharides. SusD, together with SusC, a predicted beta-barrel porin, forms the minimum outer-membrane starch-binding complex. The adult human distal gut microbiota is essential for digestion of a large variety of dietary polysaccharides, for which humans lack the necessary glycosyl hydrolases.	5.5718e-45
CP030854.1\|AXE21939.1\|20540_21113_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|187768	cd09637, Cas4_I-A_I-B_I-C_I-D_II-B, CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas4 is RecB-like nuclease with three-cysteine C-terminal cluster.	8.46678e-25
CP030854.1\|AXE21942.1\|22660_23326_-\|DNA-repair-protein	gnl\|CDD\|380073	pfam17955, Cas6b_N, Cas6b N-terminal domain. Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defense system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the invading nucleic acid for degradation. Four Cas proteins (Cas5, Cas6b, Cas7 and Cas8b) are proposed to form a Type I-B Cascade complex that mediates the antiviral defense. This is the N-terminal domain found in Cas6b proteins. Cas6b is a member of Cas6 RNA processing endoribonucleases found in bacteria and archaea whose RNA substrates have a wide range of structural features. Cocrystal structures of Cas6 from Methanococcus maripaludis (MmCas6b) bound with its repeat RNA revealed a dual-site binding structure and a cleavage site conformation poised for phosphodiester bond breakage.	9.82647e-39
CP030854.1\|AXE21945.1\|26411_27296_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	1.12971e-66
CP030854.1\|AXE21936.1\|12115_13573_+\|replication-initiation-protein	gnl\|CDD\|376444	pfam01051, Rep_3, Initiator Replication protein. This protein is an initiator of plasmid replication. RepB possesses nicking-closing (topoisomerase I) like activity. It is also able to perform a strand transfer reaction on ssDNA that contains its target. This family also includes RepA which is an E.coli protein involved in plasmid replication. The RepA protein binds to DNA repeats that flank the repA gene.	2.9345e-31
CP030854.1\|AXE21935.1\|10495_11155_-\|chromosome-partitioning-protein-ParA	gnl\|CDD\|222854	PHA02518, PHA02518, ParA-like protein; Provisional.	4.06571e-43
CP030854.1\|AXE21933.1\|5260_8569_-\|SusC/RagA-family-protein	gnl\|CDD\|274948	TIGR04056, OMP_RagA_SusC, TonB-linked outer membrane protein, SusC/RagA family. This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate].	0

>CP030854.1|AXE21938.1|16889_17393_-|hypothetical-protein
MDSSFLLPSELDLELLDYELYPDRIDLQVISTASSTCCPVCGHLSHKIHSCYHRIIHDLPASGRRVRLQLQVRKYFCKNTDCPRLIFTERFVTGLASYARRFDRLNQVLTGMGLESGGNPSTRQARYFSVKVSASTVLRLIKKCNMPSITAPKIIGVDDCRAAVAGV
>CP030854.1|AXE21971.1|16429_16792_-|hypothetical-protein
MLEHPSIAIVSRDRSNTYAAAITEACPQAEQIADRWHILKNLSETVERFLDTLRGEIKETALKLSQQQQQNSVNEEITADKSETPPIESQLQKPVFVGKYQDNMRVAAPFESQRITIEGI
>CP030854.1|AXE21937.1|15726_16401_-|hypothetical-protein
MSRRTVAKYWNRIEFVPKASRKRSNILDFENYLQQRWQEGQQSAKALYEEISDKGFTYSQATVYNMVRKYPKSVLEPLPASVKATYYSSKQLSIWLGMYQNDWEDYMPIEFLRKLLEENPLIKAVREIALEFRQLMKAKQGNQLQDWCNKALDSGVEALKGFVRGVKQDFKAIFQAFTSEWSNGQVEGQVNRLKNIKRQMYGRASFELLRKRVIMMGIPDFHQM
>CP030854.1|AXE21936.1|12115_13573_+|replication-initiation-protein
MAKKELPKRRKQDLQERYTIRIQGGKSGLVEATSKMDIHEFRVFATMLTMVLPEDEDFTTYELRVQDIIKLFSLKKDGRYYELVRDAAHKLLDRKFVIYEMKNGEEYKTTINLITETSEPVSEINKNHILLQFSPKLKPYLLQLKKEYLTIDIRNIQDISSPYSVKLYMVLKHQQRLGNYKVKYPIERLRQILAIEEGEYGLYGSFKQQVIRRTLSDIEKYTDLSVLKIEEEKAGRSVSAIIFHVVEKEAQRQNEIKIKKQQHNILKKSDGRVVVGEDGEKEPISFETAEVINVKGVQLNEIENVFQKVRKYKIAKATVRQWFNEFPIEQITLGIDHVLSEVKVGKEIKNIGGYINQMVKTSSLFEVAQEQKTEQERKRMQQQEKQQQEKTLNEQVNSLKIQAHNMRLEVLAELVQNQEIKQALIDKFSVGLFKTYYKPSLGFEENIKNPAVAGFMIATAGQLYPERFVEAEQLVKRAEALERGR
>CP030854.1|AXE21935.1|10495_11155_-|chromosome-partitioning-protein-ParA
MIITVGGIKGGSGKTTVATNLAIYISQRGGDVLLVDADDQETATDFTAWREETKMGEVGYTAVKLTGDQVRTQVAKLKSKYQYVVIDTGGRDTTSQRAALFISDIYLLPFNPRSFDVWTVGKVEKLIMEIRAVRPAELLAFSFINRADARGSDNNDAAELLAQSEVMEYLEMPLGNRKAFSHAAAKGLGVTELLPVDEKAVNELTSLFNKVLSHTNALI
>CP030854.1|AXE21934.1|10123_10441_-|hypothetical-protein
MAVSAPPKKKVPETPPVVSEEEITKVINKGGSPVNKLAKTRTRDKTKPIRAIAVSLTSEEIDSIISLRNQRPSPSRTKKIPISLHDWILEAVQEKIERERKKYQM
>CP030854.1|AXE21970.1|8630_9464_-|hypothetical-protein
MAVLFLGTADMEVKIVASTTIDSLGACQGVSYLLGKVYLYGDREVGMIRTYALNSNQLIYTGQEIKLTQNGQDVINHPTGIAHNGSKHTFVGNSIRLNPEGTQWKAVIYAVDWEGLQRTKTLDGNLLNVIEDDICIQGTRPEYVQYEGKWYVATADYGPKSNEVRLYDPQILSKAKKTSEAGVLFKKFSCSAWVQNLHWIPSKGILVLIQNQIEGRKWRFTFIDLKKSVASGQQQVLNVVDIDKSDELEGFTLLEGSSTGMAVTSSRHQNVHLVTVK
>CP030854.1|AXE21933.1|5260_8569_-|SusC/RagA-family-protein
MNIYKTPTKSWMCFCILFLGLTFLHQFPASATKLQQAIKVTGIITDEANQPLPGVSIVEKQTRKGTVSDEQGKFSLDVSTEAVLVISSVGFVPQEVVINGQTSLTIKLKEDINMLNEVVAVGYQILRKSDVTGAISNVKARELNLAAPTLGQALVGKLAGVQVSQVSGAPYVSTKIRVRGIGSINASSDPLYVIDGFPAGNDVFINPNDIESIDILKDAASAAIYGSRASGGVVIITTKRGKEGNGKMEYDYQYGVHQLAKKVKLLNSEQFAQLLIDARNNTYRDLYENSGKTWNNSMYSDDNATRVSKVGNASAVSIPTDIYDFANQKLIAPKYNTDWQNELYRNAPVSRHNLTFSGGNKGGRYLVSLGYQNQQGIIVATKQERLNFRVNVDGDLTEKLKVGASIFVTSTNGREVQEGRFNQGVVLGALIYPPTFRAYDDNGVLLKNQVAAQQPTFGYQTVENPVALALETNINRRGLRANYNGNLTYELLPGLSAKANIGLQTYNEKYEYYLPTSLSSGNNPPYSTQSYAAARATAQTLATTNLLGEFTANYTKQFGEHGINLLAGYTAQKYNSDLISVSAQGFQNDLIQEITAKGADPANFFLNGGTGKVEETLLSYLARAEYRFASRYYITAAFRRDGSSRFGPLNRWGAFPSVSAGWNISEESFYNNMLGEASTLKLRASWGLTGNYNIGNYNYLQTMANPSGTVFGNGTINTAVWAGPIKDQRLGWESTSQYNVGLDVGLLRNRLSFIFNAYLSNSYNLLFNQPVSAISGTSTILTNLRDSKVQNKGVELQIDGRLVSTKEFKLNLSGNISFNRNKVLNMGGANTIITNGAERSYLTHITQEGQPIGMFYGFKVIGMVREKDMENIAVDNANYNASKQSFPAGYVLKGPARSTASSNPLRPGDLIFEDVNKDGVVNDADKQVIGTPYPKFTYGFSLNASYRDFDLGAAFNGVYGNQVLDGQDYYVYNMEASGNQYVDVINRYRSEAEPGNGLVYRAARGGTQSNSTRLSTFYLQSGSFFRCTNLSLGYNLPTKWLGKWKVEGLRVYANVNNAFTMTKYKGYNPEVDYNGGANLTPGVDYGMYPLARAYNIGAKLTF
>CP030854.1|AXE21932.1|3699_5232_-|RagB/SusD-family-nutrient-uptake-outer-membrane-protein
MKTIRNSILCLCLTLGAMSCNDNFLVETDPNSVATSNYFKNENDVLLAVNGAYQALRNNNGLAEGSMLYSEERSDNTGRNDNQSNAGEPFQFNDFSLLPSNTYLKTHWLALYQIITRTNLVLDGIEKVTFSNATTKAQYQAEAKFIRALVYFHLVRKWGDVPLVIKPLSSSDEVKANTAREKKDKVYAQIVADLTDVVNSSLPDHQPVANKGRVSKVAGMALLGQVYLTMATTLDAANRTTNLNQAKTYLTGAYEKRTFGLLKEIAYTDVFDVAKKSTNPEIIFQIVYKQGDINYASNIAVSTQAQGENINSLRTTTGTGGNVTPDLVKEYEEGDLRKDFSIKYANAANVKDYFITKYRDVSAAAGANGYGGNDWILMRYADVILMLAEVNLYLGNDAAAIGFLNQVRERAKMPLYEVAKEAPAYKAKFPTLKMAILHERRIELAFENHRWFDLLRFFTPAELVTYMGTKLQADFGAAKISNFGLKDYYYPIPFDEFKLDPVKMYQNEGY
>CP030854.1|AXE21931.1|3274_3565_+|hypothetical-protein
MKSKIKAQASEIAKKIADVMIEEATSKKIKKAVNKTSEKLAKRIVKIKQKEAKEKDKVEKKAEKKVLKAAKKVSQEKKVKKVAKVSKKNEDATPIA
>CP030854.1|AXE21939.1|20540_21113_-|CRISPR-associated-protein-Cas4
MTLTPSHIIEYLYCPRFTYFEYVLAIPQYEEKNYKVMRGRELHDLKLEQNKDYLRRRIGAVSKHIDQYLTNDIIRGRVDEVLGLSNGTMVPLDYKFAEYKDRVYETYRTQLYCYAWLIEENFGHKVEKGFLVYTRSRNKLIEVPITEENKQEVKDTAKAIGRIIEDNFFPKATKYKARCVGCTYRNMCIR
>CP030854.1|AXE21940.1|21112_21403_-|CRISPR-associated-endonuclease-Cas2
MIIWVLYDIEKDKSRTKVSKLCEQAGLYRVQYSCFLGTLTANEKDTLRLQIEALIDEEKDKVYIFPMSKDELRNTDLLGQAFDKDLVTDQIRALFF
>CP030854.1|AXE21941.1|21448_22438_-|CRISPR-associated-endonuclease-Cas1
MHLHINTYGTYVHVKDDMFEIRKKAENGELEKKHFSANKVEGIILATGSALSTDAIKLAMMHNVDILFIEQNGEPIGRVWHAKLGSTTKIRKRQLEASLDNVGVKWTKTWLLTKLDNQLNFIKDLKKHRPQHADFLNDKITRIEALSVSISSLEARKVSEIADTLRGLEGTAGRLYFETLSYVFPKEYAFNGRSSRPAKDAFNAFLNYAYGILYGKIEKALIVAGVDPYVGFMHRDDYNQLSMVFDFIEPYRAFADEVVFRLFSAKKVNKSHVDELQNGMSLNKTGKELLVLAFTKFMDDDPIKHKGCNLVRSHVIQADAHSFANALIA
>CP030854.1|AXE21942.1|22660_23326_-|DNA-repair-protein
MTLPLTTVTFPEIPLRTRDAHKLRGYFGDFFKEHSPLLHNHYEDGSLRYAYPLVQYKVLNRVPTLVGLGEGAQLLVELFLRIRALDIDGRKIEVLSKHIDHQQAAVEVGSALVKYRFETLWMPLNQENHREYLSADDKTRQELLQRILQNNILAFLKGAGAYQPDLPRLMLLLNVQAQTTTQFKNQTMLAFTGDFVVNATLPNGIGLGKSVARGFGSIVRQ
>CP030854.1|AXE21943.1|23337_25695_-|CRISPR-associated-helicase/endonuclease-Cas3
MKDNFLPHILAKSKPEDNPETLVQHTDKLIDAWSELRKRYDSVLNKDERFWFDSFIAIIFHDFGKLSQNFQEVLRKALKRKALYKLEPLRHEFLSGMLLAYHTVVEFRKCQDLQPNYSQLFAVLTHHKNFTTSLFDGDKFVKWTIHQADFEEFIEYAKARITEHFTNQGVYLQDISYAWRILSENQENLELQYSDKDDIVEETTFGFKNSGGYEHRFDYILHKSILVASDWSASGHRNLEEPLSYTHQNIFDKVKTRVGERFKGFRQFQNISSQTKGNVLAIAPTGSGKTEASLLWAADRHHDFQRIVYLLPTRVTANALYKRMDNYFGKASNGKDDYVAVVHSSAKLFRQELDEKYDDFSYLRESSFFKSVTVGTVDQMLTQGFNVGWWELKTFHLFRAKVIIDEVHAYAPYTLGLIISSIQYLRKNFQTEFYIMTATMPSQLRDLLTEALGGKENVTLIPDNELLNKKGRNEFRILDKSVTIDTLKPEIEERLKKGKKILLVANTVDEAIRLYDAYKGFDRLCYHSRYIVKHRTEKERLIEQYETDKEGEGFLLIATQVVEVSLDIDYDYLYTENAPIDAIIQRAGRINRKRDESKETEIIVFWHREVSEKIYEDAEIPLKVLETTYNKLRERVEQKKRLSEQDLIDLVEKVYCNWKIETHPSYQKGLKKHEEIIKNFCAYVMDFDEDKENVLTREGLDTVTIIPWCFKDMLKDANSKEKSKYEVSIQKKVYQIVRGKVKRFTDNDGFEYLNVPYSFKKGVSFSKKEIEALNPKGEDKLAFCF
>CP030854.1|AXE21944.1|25691_26399_-|CRISPR-associated-protein-Cas5
MLHCVIEIRSVTASFRNPEFQNFHKSFRLPPPTTLIGLAGAALGLSPKSAQDFFEKDSFRAGVRGIASGMARDLWKYDTLPGRSVITREILMDTHYWIVFGCESQETIHQIKAAFDNPVFALTMGSSDSLAKIVKTELIESESESNELENALVEDDIIPLVLAQALKGGEFSFGVNDSDPIAYQLPTRFAYESDYGVRKIAARKLFSFIGPKVTFKDEVFRGVHFGDVFIPTFTL
>CP030854.1|AXE21945.1|26411_27296_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKTNSLTITYLAKVSFASLNGGDKEVDNINTIKKVTLENGDQLPYMSAQAVRRALRDKLQELGWSVSPVGESSEDKGAAKTAGEGGKFIDDDLFGFMDAAKAGTFVRTSPVRVEALLALNKFQEDLDFGTNYMAKDSGGNPNIFETEIHSGIYRGTILIELDRVGEELKGAGKKEFSITNEDKATRVNALIDAFQMLWSSGRQSRFLADISPKFVAAALMKSKNPIFLETLKIKRDGQVDIEALKSVTNDYAPFIDQSVFATQEGVFTKNDDTVVSLGEGFATMKGWVNSYYGV
>CP030854.1|AXE21972.1|27292_29059_-|hypothetical-protein
MKKIEFPYCNNVFLDNGIIGLYKYLLKDESLEKGTHFDLEEKRLWVEHDALFELLERTYYTMGREVYDTYTQKQEDEKGNLYFRVNNKMEMIGEPVSFPKMNTYGFTELLTNNAQGVTTKETNTLKFAEIEKKYPALSVQIKDEFEQRKVKLLSKIYLNERYTKLTRLETPTKAHFDEGSQTCYLTGNKRKKLVDAQNISPFFSGLTNFNSLLSTNDKKICWEALYLSRFSAVTSLYQYPNKLRDALNVYFVFSNNLLNLDFLISQRFMSLIKDQDSLKINEYLANFPRSEEDKKDIYLGKSNDFVGVNETLFFLIHCLYKEVLRTKPQINQSEFRRTIRNKPVGLVSIRAEAFASTMRPKQFEYVTHFSFVTELLYHLEKGGVNWRDIVQSLKILKPSLGQNKNRYELERQFRELVLGKVIKAKSILVDMEGFFDDCYGYLLDSLNDPLKAIGYKRYNDLLDFVTLYERIINHKIMTDKELQEKAIKLGAQIGQGILSYGETPERKTNARQGRKYIISLRKANQYDRFLQELARIQSRFTLNYSRDFLDSIDEERFQWVRQFVIISALNQINVELSPRKQDSNQSTK
>CP030854.1|AXE21946.1|29781_30966_-|ATPase
MIERSAKFHIEQSLDIFPAVGIVGARQVGKTTLAKVIGQESQKEVIYLDLEDFRDYQRIEVDPLLFFEQHQDKTIIIDEVQRMMTLFPMLRSAIDRYRVPARFILLGSASPTFLAKSTETLAGRIAYCELTPVSFREAVAFGKTLEQHWTKGGFPTALLLPKDEQWRLWQSNFLKTYVDSDLRLLGLNAQPLTISRLLRVLSTANGKMVSYTDIANVMDLALPTVKNYLDFLENSFIIRRLYPYFTNLGKRLVKTPKLYFRDSGMLHQLLNIGSYTQLLDHIEKGASWEGYVIEQITSQLHESAIPYFYRTQHGAELDLVIEMNNLIVATIEIKLSDSPSLSKGNHQAVVDLKCANNFILTFSAGDYALNSLWHVCDLNTIWKHLDKLGLLHHP
>CP030854.1|AXE21947.1|31057_31966_-|transcriptional-regulator
MASFTNDDSSPEQAKIERVLRLISLLKDRKRTVPQLARAVNTSPRSLYRYLKLLEKIGYHLENDEQNRYWIFEGESSKINFTVEETALLRPLLAGLKVSGPLYASIERKIYLTSELVPLASELLDLRRARIVSQLNDAIKDKRRVRLLRYHSSNSNTTTDRLVEPLSFTDDFSTLNAYEPESQKVKTFKVSRMEDLEVLAELQENELPGPEVDIFGWTGPEPIFVELQLTSTAYQLLMEEYPAARPFAGRTSSPPFAFRLGVEVRDFTGIGRFILGLHQNIAVVQPQGLKDYLNGIVAGMRF

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP030854_1	1.1\|11509\|40\|CP030854\|PILER-CR	11509-11548	40	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	11509-11548	0	1.0
CP030854_2	2.1\|15292\|35\|CP030854\|CRT	15292-15326	35	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15292-15326	0	1.0
CP030854_2	2.2\|15357\|37\|CP030854\|CRT,PILER-CR	15357-15393	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15357-15393	0	1.0
CP030854_2	2.3\|15424\|36\|CP030854\|CRT,PILER-CR	15424-15459	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15424-15459	0	1.0
CP030854_2	2.4\|15490\|37\|CP030854\|CRT,PILER-CR	15490-15526	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15490-15526	0	1.0
CP030854_2	2.5\|15557\|34\|CP030854\|CRT,PILER-CR	15557-15590	34	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15557-15590	0	1.0
CP030854_2	2.6\|15621\|37\|CP030854\|CRT,PILER-CR	15621-15657	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15621-15657	0	1.0
CP030854_2	2.7\|15355\|39\|CP030854\|CRISPRCasFinder	15355-15393	39	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15355-15393	0	1.0
CP030854_2	2.8\|15422\|38\|CP030854\|CRISPRCasFinder	15422-15459	38	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15422-15459	0	1.0
CP030854_2	2.9\|15488\|39\|CP030854\|CRISPRCasFinder	15488-15526	39	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15488-15526	0	1.0
CP030854_2	2.10\|15555\|36\|CP030854\|CRISPRCasFinder	15555-15590	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15555-15590	0	1.0
CP030854_2	2.11\|15619\|39\|CP030854\|CRISPRCasFinder	15619-15657	39	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	15619-15657	0	1.0
CP030854_3	3.1\|17537\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	17537-17573	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	17537-17573	0	1.0
CP030854_3	3.2\|17611\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	17611-17646	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	17611-17646	0	1.0
CP030854_3	3.3\|17684\|40\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	17684-17723	40	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	17684-17723	0	1.0
CP030854_3	3.4\|17761\|38\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	17761-17798	38	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	17761-17798	0	1.0
CP030854_3	3.5\|17836\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	17836-17871	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	17836-17871	0	1.0
CP030854_3	3.6\|17909\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	17909-17945	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	17909-17945	0	1.0
CP030854_3	3.7\|17983\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	17983-18018	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	17983-18018	0	1.0
CP030854_3	3.8\|18056\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18056-18091	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18056-18091	0	1.0
CP030854_3	3.9\|18129\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18129-18164	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18129-18164	0	1.0
CP030854_3	3.10\|18202\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18202-18237	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18202-18237	0	1.0
CP030854_3	3.11\|18275\|38\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18275-18312	38	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18275-18312	0	1.0
CP030854_3	3.12\|18350\|35\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18350-18384	35	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18350-18384	0	1.0
CP030854_3	3.13\|18422\|35\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18422-18456	35	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18422-18456	0	1.0
CP030854_3	3.14\|18494\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18494-18529	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18494-18529	0	1.0
CP030854_3	3.15\|18567\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18567-18602	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18567-18602	0	1.0
CP030854_3	3.16\|18640\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18640-18676	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18640-18676	0	1.0
CP030854_3	3.17\|18714\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18714-18750	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18714-18750	0	1.0
CP030854_3	3.18\|18788\|35\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18788-18822	35	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18788-18822	0	1.0
CP030854_3	3.19\|18860\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18860-18896	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18860-18896	0	1.0
CP030854_3	3.20\|18934\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	18934-18970	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	18934-18970	0	1.0
CP030854_3	3.21\|19008\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19008-19044	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19008-19044	0	1.0
CP030854_3	3.22\|19082\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19082-19117	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19082-19117	0	1.0
CP030854_3	3.23\|19155\|38\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19155-19192	38	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19155-19192	0	1.0
CP030854_3	3.24\|19230\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19230-19266	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19230-19266	0	1.0
CP030854_3	3.25\|19304\|39\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19304-19342	39	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19304-19342	0	1.0
CP030854_3	3.26\|19380\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19380-19416	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19380-19416	0	1.0
CP030854_3	3.27\|19454\|38\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19454-19491	38	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19454-19491	0	1.0
CP030854_3	3.28\|19529\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19529-19564	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19529-19564	0	1.0
CP030854_3	3.29\|19602\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19602-19637	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19602-19637	0	1.0
CP030854_3	3.30\|19675\|38\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19675-19712	38	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19675-19712	0	1.0
CP030854_3	3.31\|19750\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19750-19786	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19750-19786	0	1.0
CP030854_3	3.32\|19824\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19824-19859	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19824-19859	0	1.0
CP030854_3	3.33\|19897\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19897-19932	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19897-19932	0	1.0
CP030854_3	3.34\|19970\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	19970-20005	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	19970-20005	0	1.0
CP030854_3	3.35\|20043\|35\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	20043-20077	35	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	20043-20077	0	1.0
CP030854_3	3.36\|20115\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	20115-20150	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	20115-20150	0	1.0
CP030854_3	3.37\|20188\|36\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	20188-20223	36	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	20188-20223	0	1.0
CP030854_3	3.38\|20261\|37\|CP030854\|PILER-CR,CRISPRCasFinder,CRT	20261-20297	37	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	20261-20297	0	1.0
CP030854_1	1.2\|11584\|72\|CP030854\|PILER-CR	11584-11655	72	NZ_CP030854	Runella sp. HYN0085 plasmid unnamed4, complete sequence	11570-11641	12	0.833

1. spacer 1.1|11509|40|CP030854|PILER-CR matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ctttaaaaaatcggtaaataggaatctcccttcttcaatc	CRISPR spacer
ctttaaaaaatcggtaaataggaatctcccttcttcaatc	Protospacer
****************************************

2. spacer 2.1|15292|35|CP030854|CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tcggcctgtaacattgcttgcagagtgttaccgct	CRISPR spacer
tcggcctgtaacattgcttgcagagtgttaccgct	Protospacer
***********************************

3. spacer 2.2|15357|37|CP030854|CRT,PILER-CR matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

actatggatgattgggctaagttcatgcagatgcgtt	CRISPR spacer
actatggatgattgggctaagttcatgcagatgcgtt	Protospacer
*************************************

4. spacer 2.3|15424|36|CP030854|CRT,PILER-CR matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ccgtttcagcacgtttgtagccatcggtgacatatc	CRISPR spacer
ccgtttcagcacgtttgtagccatcggtgacatatc	Protospacer
************************************

5. spacer 2.4|15490|37|CP030854|CRT,PILER-CR matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tcaatcagcttatcttcggcggctgaatagaactgcg	CRISPR spacer
tcaatcagcttatcttcggcggctgaatagaactgcg	Protospacer
*************************************

6. spacer 2.5|15557|34|CP030854|CRT,PILER-CR matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tcagagggcggggattgatagagttttctattac	CRISPR spacer
tcagagggcggggattgatagagttttctattac	Protospacer
**********************************

7. spacer 2.6|15621|37|CP030854|CRT,PILER-CR matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tgatagaccgcaaaacgggcgctgaagtaggagaaat	CRISPR spacer
tgatagaccgcaaaacgggcgctgaagtaggagaaat	Protospacer
*************************************

8. spacer 2.7|15355|39|CP030854|CRISPRCasFinder matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ggactatggatgattgggctaagttcatgcagatgcgtt	CRISPR spacer
ggactatggatgattgggctaagttcatgcagatgcgtt	Protospacer
***************************************

9. spacer 2.8|15422|38|CP030854|CRISPRCasFinder matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ggccgtttcagcacgtttgtagccatcggtgacatatc	CRISPR spacer
ggccgtttcagcacgtttgtagccatcggtgacatatc	Protospacer
**************************************

10. spacer 2.9|15488|39|CP030854|CRISPRCasFinder matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ggtcaatcagcttatcttcggcggctgaatagaactgcg	CRISPR spacer
ggtcaatcagcttatcttcggcggctgaatagaactgcg	Protospacer
***************************************

11. spacer 2.10|15555|36|CP030854|CRISPRCasFinder matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ggtcagagggcggggattgatagagttttctattac	CRISPR spacer
ggtcagagggcggggattgatagagttttctattac	Protospacer
************************************

12. spacer 2.11|15619|39|CP030854|CRISPRCasFinder matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

agtgatagaccgcaaaacgggcgctgaagtaggagaaat	CRISPR spacer
agtgatagaccgcaaaacgggcgctgaagtaggagaaat	Protospacer
***************************************

13. spacer 3.1|17537|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tgaagattgcgagcaagctggccgaattgaaaaacta	CRISPR spacer
tgaagattgcgagcaagctggccgaattgaaaaacta	Protospacer
*************************************

14. spacer 3.2|17611|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ctattcgggcactaaccccttgcccgtgtacattag	CRISPR spacer
ctattcgggcactaaccccttgcccgtgtacattag	Protospacer
************************************

15. spacer 3.3|17684|40|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

acatagacgctaattgtcgggttaggttacccggcttgct	CRISPR spacer
acatagacgctaattgtcgggttaggttacccggcttgct	Protospacer
****************************************

16. spacer 3.4|17761|38|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

acgcggcaaaaagtagaaatacccgcccaaagaaccaa	CRISPR spacer
acgcggcaaaaagtagaaatacccgcccaaagaaccaa	Protospacer
**************************************

17. spacer 3.5|17836|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tccgggacgatttaagaaggcgcaagtctcttggaa	CRISPR spacer
tccgggacgatttaagaaggcgcaagtctcttggaa	Protospacer
************************************

18. spacer 3.6|17909|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ctgctactgcacaagtgaacaaaagcccaccaagcag	CRISPR spacer
ctgctactgcacaagtgaacaaaagcccaccaagcag	Protospacer
*************************************

19. spacer 3.7|17983|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

aatttggaataagcatttagatagcttggattatgt	CRISPR spacer
aatttggaataagcatttagatagcttggattatgt	Protospacer
************************************

20. spacer 3.8|18056|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

caaggcgtttgcataggctgaaccatccgcaagggt	CRISPR spacer
caaggcgtttgcataggctgaaccatccgcaagggt	Protospacer
************************************

21. spacer 3.9|18129|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tatttttatttcttgcccttgctccatgtgtggata	CRISPR spacer
tatttttatttcttgcccttgctccatgtgtggata	Protospacer
************************************

22. spacer 3.10|18202|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ccaacaacgccaaccccaacaacggcaaacgagttt	CRISPR spacer
ccaacaacgccaaccccaacaacggcaaacgagttt	Protospacer
************************************

23. spacer 3.11|18275|38|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

gttgcgtttccgtttctggtgggcctgattcactaccg	CRISPR spacer
gttgcgtttccgtttctggtgggcctgattcactaccg	Protospacer
**************************************

24. spacer 3.12|18350|35|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

actaagaaagatatttgaagtgttgggcgaaccat	CRISPR spacer
actaagaaagatatttgaagtgttgggcgaaccat	Protospacer
***********************************

25. spacer 3.13|18422|35|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tttttcaaaagacctctatcaactcccattttaaa	CRISPR spacer
tttttcaaaagacctctatcaactcccattttaaa	Protospacer
***********************************

26. spacer 3.14|18494|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

gttgattggtgagcattgccaacgcctgatttccct	CRISPR spacer
gttgattggtgagcattgccaacgcctgatttccct	Protospacer
************************************

27. spacer 3.15|18567|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

atttgaggcgattatcaagtattacgagctagtgcg	CRISPR spacer
atttgaggcgattatcaagtattacgagctagtgcg	Protospacer
************************************

28. spacer 3.16|18640|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

agcggcgaggattgtaaggttaaaatcagaaaccacg	CRISPR spacer
agcggcgaggattgtaaggttaaaatcagaaaccacg	Protospacer
*************************************

29. spacer 3.17|18714|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

caaaagcagatgtagtcaatttgcttagtaacaggcg	CRISPR spacer
caaaagcagatgtagtcaatttgcttagtaacaggcg	Protospacer
*************************************

30. spacer 3.18|18788|35|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

gcggctctttttatcattgagcgtatcaggaagta	CRISPR spacer
gcggctctttttatcattgagcgtatcaggaagta	Protospacer
***********************************

31. spacer 3.19|18860|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

gtacttttcaggctacgattttaggcacgatgtcgga	CRISPR spacer
gtacttttcaggctacgattttaggcacgatgtcgga	Protospacer
*************************************

32. spacer 3.20|18934|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ttggaaatttgaagtttgaacacgcttgggtcaatgc	CRISPR spacer
ttggaaatttgaagtttgaacacgcttgggtcaatgc	Protospacer
*************************************

33. spacer 3.21|19008|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

gggaaccttaatttttacaagttcagaacggaaaacc	CRISPR spacer
gggaaccttaatttttacaagttcagaacggaaaacc	Protospacer
*************************************

34. spacer 3.22|19082|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tacaaaagcagggtattttcaagccgttcaatcgta	CRISPR spacer
tacaaaagcagggtattttcaagccgttcaatcgta	Protospacer
************************************

35. spacer 3.23|19155|38|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ctggtcatcagtaaggcccacattttccttaattgtat	CRISPR spacer
ctggtcatcagtaaggcccacattttccttaattgtat	Protospacer
**************************************

36. spacer 3.24|19230|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

atcgctacgggagaagatagagttgcaaccaatgccg	CRISPR spacer
atcgctacgggagaagatagagttgcaaccaatgccg	Protospacer
*************************************

37. spacer 3.25|19304|39|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

atgttctgaaatacgtacgatcatacatcaaccatgcca	CRISPR spacer
atgttctgaaatacgtacgatcatacatcaaccatgcca	Protospacer
***************************************

38. spacer 3.26|19380|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ctgagggctttcatatcttttatgcgtccgtaccctt	CRISPR spacer
ctgagggctttcatatcttttatgcgtccgtaccctt	Protospacer
*************************************

39. spacer 3.27|19454|38|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

agacctgtcgcggctaagaatcatttctgggaaaacgt	CRISPR spacer
agacctgtcgcggctaagaatcatttctgggaaaacgt	Protospacer
**************************************

40. spacer 3.28|19529|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tccaatctactgccccgttgttccatgtcagcttag	CRISPR spacer
tccaatctactgccccgttgttccatgtcagcttag	Protospacer
************************************

41. spacer 3.29|19602|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

cttcaaattttcagttgagaaccgctacaggatggg	CRISPR spacer
cttcaaattttcagttgagaaccgctacaggatggg	Protospacer
************************************

42. spacer 3.30|19675|38|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

tctaccttgaaacattttattgatttttatagggttga	CRISPR spacer
tctaccttgaaacattttattgatttttatagggttga	Protospacer
**************************************

43. spacer 3.31|19750|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

aagtcctgaagaaccaacccccatacaatatcagcgt	CRISPR spacer
aagtcctgaagaaccaacccccatacaatatcagcgt	Protospacer
*************************************

44. spacer 3.32|19824|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

gtatttgttgcggtaccatcaacggtaaatctgaca	CRISPR spacer
gtatttgttgcggtaccatcaacggtaaatctgaca	Protospacer
************************************

45. spacer 3.33|19897|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ttacaacgcaaaccgggccgcttttgacaagaccaa	CRISPR spacer
ttacaacgcaaaccgggccgcttttgacaagaccaa	Protospacer
************************************

46. spacer 3.34|19970|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ttggcgtacaaaaaaaagccctcgtgctgagggcta	CRISPR spacer
ttggcgtacaaaaaaaagccctcgtgctgagggcta	Protospacer
************************************

47. spacer 3.35|20043|35|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ttgagcgttctttagtgcctgaaaactttgattta	CRISPR spacer
ttgagcgttctttagtgcctgaaaactttgattta	Protospacer
***********************************

48. spacer 3.36|20115|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ataagcccgatgtgggcaagcaggtggatgaatgga	CRISPR spacer
ataagcccgatgtgggcaagcaggtggatgaatgga	Protospacer
************************************

49. spacer 3.37|20188|36|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

ctattctcggcctttttacccgaaactttttcctga	CRISPR spacer
ctattctcggcctttttacccgaaactttttcctga	Protospacer
************************************

50. spacer 3.38|20261|37|CP030854|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 0, identity: 1.0

attgtctgagcatagcccgttgcagacgtctgctcta	CRISPR spacer
attgtctgagcatagcccgttgcagacgtctgctcta	Protospacer
*************************************

51. spacer 1.2|11584|72|CP030854|PILER-CR matches to NZ_CP030854 (Runella sp. HYN0085 plasmid unnamed4, complete sequence) position: , mismatch: 12, identity: 0.833

gaggtataatatttataatatactgataatcaagagattttatttaaacatattaaacga	CRISPR spacer
gaggtataatatttataatatactgataatcaagagattttatttaaacatattaaacga	Protospacer
************************************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage