CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP021773	Streptococcus agalactiae strain B105 chromosome, complete genome	1 crisprs	DEDDh,RT,csm6,csn2,cas2,cas1,cas9,DinG,cas3,csa3	0	9	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP021773_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP021773_1

1083273-1083836

TypeII

II-A

Consensus_repeat	Method
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CRT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	PILER-CR
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	PILER-CR

8 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of CP021773_1

>merge|CP021773|1|1083273-1083836|CRT,PILER-CR,CRISPRCasFinder,PILER-CR
CGGTGCCCTAGCATAATAACCGCACAGCTCTAAAACACATATCAGGAATATAAAAATCGTTCAAATGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTGCCTTTTAATTCAGCTCCCACTTTTTATCGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACCGATTTGCTCGTACATTATAAATACCACCAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTTGTATATGACCCGTTACCGCTATCAAATAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTACCTGGAATGTTAAATTTACCTTTTAGCAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACATGTTGCCACTAGTTGCTCTTTATGAACAGGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACAGTTTCTTTTAAGTTCAATGTTTGTCAAATGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTTTACATTAAAAAAATGGACGAGCGGTCAAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

>CP021773|1|1|1083273-1083836|CRT
CGGTGCCCTAGCATAATAACCGCACAGCTCTAAAAC	ACATATCAGGAATATAAAAATCGTTCAAAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TGCCTTTTAATTCAGCTCCCACTTTTTATC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CGATTTGCTCGTACATTATAAATACCACCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTGTATATGACCCGTTACCGCTATCAAATA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TACCTGGAATGTTAAATTTACCTTTTAGCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATGTTGCCACTAGTTGCTCTTTATGAACAG
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	AGTTTCTTTTAAGTTCAATGTTTGTCAAAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTTACATTAAAAAAATGGACGAGCGGTCAA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

>CP021773|1|1|1083339-1083572|PILER-CR
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TGCCTTTTAATTCAGCTCCCACTTTTTATC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CGATTTGCTCGTACATTATAAATACCACCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTGTATATGACCCGTTACCGCTATCAAATA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTACCTGGAATGTTAAATTTACCTTTTAGCAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATGTTGCCACTAGTTGCTCTTTATGAACAG
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	AGTTTCTTTTAAGTTCAATGTTTGTCAAAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTTACATTAAAAAAATGGACGAGCGGTCAA


>CP021773|1|1|1083339-1083836|CRISPRCasFinder
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TGCCTTTTAATTCAGCTCCCACTTTTTATC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CGATTTGCTCGTACATTATAAATACCACCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTGTATATGACCCGTTACCGCTATCAAATA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TACCTGGAATGTTAAATTTACCTTTTAGCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATGTTGCCACTAGTTGCTCTTTATGAACAG
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	AGTTTCTTTTAAGTTCAATGTTTGTCAAAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTTACATTAAAAAAATGGACGAGCGGTCAA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

>CP021773|1|2|1083603-1083836|PILER-CR
	TGCCTTTTAATTCAGCTCCCACTTTTTATC
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	CGATTTGCTCGTACATTATAAATACCACCA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTGTATATGACCCGTTACCGCTATCAAATA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAACTACCTGGAATGTTAAATTTACCTTTTAGCAGTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	ATGTTGCCACTAGTTGCTCTTTATGAACAG
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	AGTTTCTTTTAAGTTCAATGTTTGTCAAAT
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC	TTTACATTAAAAAAATGGACGAGCGGTCAA
GTTTTGGAACCATTCGAAACAGCACAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP021773.1\|AWZ36272.1\|1077452_1080086_-\|internalin	unknown	unknown	gnl\|CDD\|275380
CP021773.1\|AWZ36282.1\|1093570_1093951_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131381
CP021773.1\|AWZ36267.1\|1070983_1071622_+\|chloramphenicol-acetyltransferase	unknown	unknown	gnl\|CDD\|100040
CP021773.1\|AWZ36269.1\|1072842_1075635_-\|haloacid-dehalogenase	unknown	unknown	gnl\|CDD\|223550
CP021773.1\|AWZ36276.1\|1084588_1084930_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
CP021773.1\|AWZ36280.1\|1091606_1092344_-\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|366738
CP021773.1\|AWZ36273.1\|1080331_1082164_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
CP021773.1\|AWZ37380.1\|1090189_1090846_-\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
CP021773.1\|AWZ36266.1\|1069661_1070273_-\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
CP021773.1\|AWZ36274.1\|1082299_1082716_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
CP021773.1\|AWZ36277.1\|1084926_1085796_-\|subtype-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
CP021773.1\|AWZ37379.1\|1076693_1077305_-\|phosphohydrolase	unknown	unknown	gnl\|CDD\|224336
CP021773.1\|AWZ36275.1\|1083936_1084602_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
CP021773.1\|AWZ36283.1\|1093975_1094347_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377982
CP021773.1\|AWZ36281.1\|1092347_1093478_-\|coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
CP021773.1\|AWZ36278.1\|1085797_1089910_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
CP021773.1\|AWZ36271.1\|1076220_1076685_-\|N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
CP021773.1\|AWZ36268.1\|1071739_1072843_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371412
CP021773.1\|AWZ36279.1\|1090835_1091606_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
CP021773.1\|AWZ36270.1\|1075783_1076221_-\|peptide-methionine-(R)-S-oxide-reductase	unknown	unknown	gnl\|CDD\|234692

Protein	Function_ID	Function_description	E-value
CP021773.1\|AWZ36272.1\|1077452_1080086_-\|internalin	gnl\|CDD\|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	2.83221e-22
CP021773.1\|AWZ36282.1\|1093570_1093951_-\|hypothetical-protein	gnl\|CDD\|131381	TIGR02328, TIGR02328, conserved hypothetical protein. Members of this protein are found in a small number of taxonomically well separated species, yet are strongly conserved, suggesting lateral gene transfer. Members are found in Treponema denticola, Clostridium acetobutylicum, and several of the Firmicutes. The function of this protein is unknown. [Hypothetical proteins, Conserved].	6.45558e-80
CP021773.1\|AWZ36267.1\|1070983_1071622_+\|chloramphenicol-acetyltransferase	gnl\|CDD\|100040	cd03349, LbH_XAT, Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. Members of this class of enzymes include Enterococcus faecium streptogramin A acetyltransferase and Pseudomonas aeruginosa chloramphenicol acetyltransferase. They contain repeated copies of a six-residue hexapeptide repeat sequence motif (X-[STAV]-X-[LIV]-[GAED]-X) and adopt a left-handed parallel beta helix (LbH) structure. The active enzyme is a trimer with CoA and substrate binding sites at the interface of two separate LbH subunits. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients.	1.14428e-70
CP021773.1\|AWZ36269.1\|1072842_1075635_-\|haloacid-dehalogenase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
CP021773.1\|AWZ36276.1\|1084588_1084930_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.83127e-50
CP021773.1\|AWZ36280.1\|1091606_1092344_-\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|366738	pfam01643, Acyl-ACP_TE, Acyl-ACP thioesterase. This family consists of various acyl-acyl carrier protein (ACP) thioesterases (TE) these terminate fatty acyl group extension via hydrolysing an acyl group on a fatty acid.	3.68196e-111
CP021773.1\|AWZ36273.1\|1080331_1082164_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
CP021773.1\|AWZ37380.1\|1090189_1090846_-\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	9.75792e-52
CP021773.1\|AWZ36266.1\|1069661_1070273_-\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	6.1265e-31
CP021773.1\|AWZ36274.1\|1082299_1082716_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	1.21474e-79
CP021773.1\|AWZ36277.1\|1084926_1085796_-\|subtype-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.45885e-137
CP021773.1\|AWZ37379.1\|1076693_1077305_-\|phosphohydrolase	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	9.46885e-34
CP021773.1\|AWZ36275.1\|1083936_1084602_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	4.57126e-122
CP021773.1\|AWZ36283.1\|1093975_1094347_-\|hypothetical-protein	gnl\|CDD\|377982	pfam08349, DUF1722, Protein of unknown function (DUF1722). This domain of unknown function is found in bacteria and archaea and is homologous to the hypothetical protein ybgA from E. coli.	6.08694e-28
CP021773.1\|AWZ36281.1\|1092347_1093478_-\|coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
CP021773.1\|AWZ36278.1\|1085797_1089910_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
CP021773.1\|AWZ36271.1\|1076220_1076685_-\|N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.76832e-16
CP021773.1\|AWZ36268.1\|1071739_1072843_-\|hypothetical-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	1.12954e-104
CP021773.1\|AWZ36279.1\|1090835_1091606_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.19143e-132
CP021773.1\|AWZ36270.1\|1075783_1076221_-\|peptide-methionine-(R)-S-oxide-reductase	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	9.78399e-86

>CP021773.1|AWZ36274.1|1082299_1082716_-|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVKRGFIGEVISRIERRGFSIDRLEVRHADADILKRHYAELTDRPFFPTLVDYMTSGPVIIGVISGEEVISTWRTMMGSTNPKDALPGTIRGDFAQAPSPNQATCNIVHGSDSPESAAREIAIWFNN
>CP021773.1|AWZ36273.1|1080331_1082164_-|elongation-factor-4
MNIEDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRAEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGEVDAPLQALIFDSVYDAYRGVILQVRIVNGMVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYIAASIKTVADTRVGDTITLANNPAIDPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSEFPDPTRVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRRSQLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDDDKK
>CP021773.1|AWZ36272.1|1077452_1080086_-|internalin
MKGQKIIALAGLVLSCHFALTACHTQEHKNSYHIKTKQVAKKKANKKKVSVKESHKKRKGVAGVDFPTDDGFLLTKDSKILSHTDSGIVVAHGNHSHFIFYSDLKGSKFSYLIPNANAKTNKNQAVRNFKAGAVAVNTLNDGYVFNPADIVSEDANGYVVRHGDHFHYIPKASLSQQKQVQASRAVSRLGNQSNSHYRVNSSKIAGLHYPTSDGFLFNGRGIKGTTPTGILVEHHNHLHFISFADLRKGGWGSIADRYQPQKKADSKKQSPSSKKPRNENTLPKDIKDKLAYLARELHLDISRIRVLKTLNGEIGFEYPHDDHTHVIMAKDIDLSKPIPNPHHDDEDHHKGHHHDESDHKHEEHEHTKSNKLSDENQKKLIYLAEKLGLNPNQIEVLTSEDGSIIFKYPHDDHSHTIASKDIEIGKPIPDGHHDHSHAKDKVGMATLKQIGFDDEIIQDILHADAPTPFPSNETNPEKMRQWLATVTKINIGQRTNPFQRFGLSLMPNIEVLGIGFTPINDMTPVLQFKKLKQLWMTNTGITDYSFLDKMPLLEGLDISQNGIKDLSFLTKYKQLSLIAAANNGITSLKPLAELPNLQFLVLSHNNISDLTPLSNLTKLQELHLDHNNVKNLSALSGKKDLKVLDLSNNKSADLSTLKTTSLETLLLNETNTSNLSFLKQNPKVSNLTINNAKLSSLDGIEESDEIVKVEAEGNQIKSLVLKNKQGSLKFLNVTNNQLTSLEGVNNYTSLETLSVSRNKLKSLDIKTPNKTVTNLDFSHNNVPTSQLKLNEKNIPEAVAKNFPAVVEGSMVGNGSLAEKAAMASKEDKQVSDNTNHQKNTEKSAQANADSKKENPKTHDEHHDHEETDHAHVGHHHH
>CP021773.1|AWZ37379.1|1076693_1077305_-|phosphohydrolase
MVYHKLKNDPSGHDWFHIVRVRNLAVELAHKEGANTFICQMAALLHDIIDDKICQDSKQASYELTQWLYSQDLAIAEVEHILDILENISFKAGTGLTMKTLEGQIVQDADRLDAMGAIGIARTMAYSGSKGRLIHDPNLKPRENLTLEEYRNGQDTAIMHFYEKLLKLKDLMNTKQGKMLAQKRHDFLELYLAEFYAEWNGKG
>CP021773.1|AWZ36271.1|1076220_1076685_-|N-acetyltransferase
MIRRAKEKDLPAIAELLKQILVLHHGVRPDIFHTRGSKFSKEQLKEMLMDESRPIFVYESDEGKVVAHLFLQLQEKRDLPRKSFKTLYIDDLCIDEEVRGQQIGQKLMDFARQCAKKHGCYNITLNVWNDNQRAVSFYEKLGFKPQQTQMEEIL
>CP021773.1|AWZ36270.1|1075783_1076221_-|peptide-methionine-(R)-S-oxide-reductase
MKETQEELRQRIGHTAYQVTQNSATEHAFTGKYDDFFEEGIYVDIVSGEVLFSSLDKFQSGCGWPAFSKPIENRMVTNHQDHSHGMHRIEVRSRQADSHLGHVFNDGPVDAGGLRYCINSAALDFIPYDQMAKRGYGDYLSLFDE
>CP021773.1|AWZ36269.1|1072842_1075635_-|haloacid-dehalogenase
MASTNNVSDTNTRFAKEELEEVFEELGTTQGGLSDEEVAVRQKKYGLNLLSEVKQESIILLFLKNFTSLMAILLWVGGFVAIVSNSLELGLAIWMVNVINGIFSFIQEYRASQATQALKKMLPSYSRVLRKSSEEKVLSEQLVPGDIVLIEEGDCISADGRLIKTTDLQVNQSALTGESNPIYKDSNVENYQSKTLIECDNMVFAGTTVSSGSATMVVTAIGMQTQFGQIADLTQGMKSEKSPLQRELDRLTKQISIISITVGIIFFLAATFFVKEPVSKSFIFALGMIVAFIPEGLLPTVTLSLAMAVQRMAKEHALVKKLSSVETLGATSVICSDKTGTLTQNEMTVNHLWQNGKSYQVTGLGYAPEGQILFEGDNICFGNSDRGDLEKLIRFAHLCSNAQVLPPNDDRSTYTVLGDPTEACLNVLLEKSGINIQENRKFAPRLKELPFDSVRKRMTTIHSLGGDEKDKKISITKGAPKEILDLSDYVLSDGKVIPLNKEERNKIQLANDTFAKDGLRVLAVSYCDIEGFSKEQWTQENLEQHMVFIGLIAMSDPPREGVREAIDKCHAASIRIIMVTGDYGLTALSIAKNIGIIRNDDAKVISGLELSEMTDSQLKKELSGEVVFARVAPEQKYRVVTILQEMGEVVAVTGDGVNDAPALKKSDIGVAMGVTGTDVAKESADMILTDDHFASIVHAVEEGRAVYQNIKKFLTYIFNSNTPEAVPSAFFLFSKGFIPLPLTVMQILAVDLGTDMLPALGLGVEPPETDVMNRPPRRLTDRLLDKGLLIKSFLWYGTIESVLAMGGFFWAHYLRYGNFTFFVANGIPYREATTMTLGAIIFSQIGMVMNSRTSYQSIKTLSIFGNKLINFGIIMEILAFLVLVYVPLFHNLFNTASLGLSHWLYLISCPFIMIGLDEVRKLFSSRKNKR
>CP021773.1|AWZ36268.1|1071739_1072843_-|hypothetical-protein
MSNIITYLKNNSNLTFDELALNDVDILCLNEFGYISFEKLINTTEMKSVLVCELYHEYLQTMAKSYSFMFTSQRHDLCQLMMTSKRFKNLTLSYYQAEISLEFEKQFAAMVFTIPNIDYHQVVFRGTDANLIGWKEDFKLTYMREISAHRSAIKYLNTILPYFDKVVLSGHSKGGNLALYAAMFTKPDLKAKIDLIWLIDSPGLQKTLLPTTEYKTTKQKCIRLLPEESIVGMMLYSDIEPLIISSNARGILQHDVTTWEIQEPAILKTGAGLSLKSICFEKTFQQWMAELKSQERKLFFDLLFDSFLSSGVSSLDDFNLASRAKMMKAFHSFRELDDDKKRLFNKSLKLLVTIFWGAYHDNSRETK
>CP021773.1|AWZ36267.1|1070983_1071622_+|chloramphenicol-acetyltransferase
MASILKKHLEKRLELKNDPMRTDMSTGASYPKYGFSVGKYTYGYQQFFYEGVNLKEIGAFCSIAQNVTITGMNHPTDHITTNPFIYYKSRGFINEDRADLIDEKKNGKVIIGNDVWIGTNVTILPSVTIGNGAIIEAGSVITKDIPDYAVVAGTPAKIIKYRFSEEEITLLNASQWWNWSDEAIKEHISEFSDKREFFNTLKSISENKNHKL
>CP021773.1|AWZ36266.1|1069661_1070273_-|TVP38/TMEM64-family-protein
MNMKLSKRYRFWQKVIKALGVLALIATLVLVVYLYKLGILNDSNELKDLVHKYEFWGPMIFIVAQIVQIVFPVIPGGVTTVAGFLIFGPTLGFIYNYIGIIIGSVILFWLVKFYGRKFVLLFMDQKTFDKYESKLETSGYEKFFIFCMASPISPADIMVMITGLSNMSIKRFVTIIMITKPISIIGYSYLWIYGGDILKNFLN
>CP021773.1|AWZ36275.1|1083936_1084602_-|type-II-A-CRISPR-associated-protein-Csn2
MIKINFPILDEPLVLSNATILTIEDVSVYSSLVKHFYQYDVDEHLKLFDDKQKSLKATELMMVTDILGYDVNSAPILKLIHGDLENQFNEKPEVKSMVEKLAATITELIAFECLENELDLEYDEITILELIKALGVKIETQSDTIFEKCFEIIQVYHYLTKKNLLVFVNSGAYLTKDEVIKLCEYINLMQKSVLFLEPRRLYDLPQYVIDKDYFLIGENMV
>CP021773.1|AWZ36276.1|1084588_1084930_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTETVEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNTANNAMIGRLKVNNPKKGNITLLTVTEKQFARMVYLHGERNTSVANFDSRLVFLGDSYDQD
>CP021773.1|AWZ36277.1|1084926_1085796_-|subtype-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLVFKDSYQTEMIHLSEIDILIMETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARYDSSLQLSRQMSWIEDVKADVWTSIIAQKILNQSFYLGECSFFEKSQSIMNLYHDLESFDTSNREGHAARIYFNTLFGNDFSREHDNPINAGLDYGYSLLLSMFAREVVKCGCMTQFGLKHANQFNQFNLASDIMEPFRPIVDRIIYENRQSDFVKMKRELFSMFSETYSYDGKEMYLSNIVSDYTKKVIKSLNSDGNGIPEFRI
>CP021773.1|AWZ36278.1|1085797_1089910_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MNKPYSIGLDIGTNSVGYSVVTDDYKVPAKKMRVLGNTDKEYIKKNLIGALLFDGGNTASDRRLKRTARRRYTRRRNRILYLQEIFAEEMSKVDDSFFHRLEDSFLVEDDKRGSKYPIFATMQEEKDYHEKFPTIYHLRKELADKKEKANLRLVYLALAHIIKFRGHFLIEDDSFDVRNTDIQRQYQAFLEIFDTTFENNHLLSQNIDVEGILTDKISKSAKKDRILAQYPNQKSTGIFAEFLKLIVGNQADFKKHFNLEDKTPLQFAKDSYDEDLENLLGQIGDEFADLFSVAKKLYDSVLLSGILTVTDLSTKAPLSASMIQRYDEHREDLKQLKQFVKASLPEKYQEIFTDSSKDGYAGYIEGKTNQGAFYKYLSKLLTKQEGSEYFLEKIKNEDFLRKQRTFDNGSIPHQVHLTELKAIIRRQSEYYPFLKENLDRIEKILTFRIPYYVGPLAREKSDFAWMTRKTDDSIRPWNFEELVDKEASAEAFIHRMTNNDLYLPEEKVLPKHSLIYEKFTVYNELTKVRYKNEQGETYFFDSNIKQEIFDGVFKEHRKVSKKKLLDFLAKEYEEFRIVDVIGLDKENKAFNASLGTYHDLKKILDKDFLDNPDNESILEDIVQTLTLFEDREMIKKRLENYKDLFTESQLKKLYRRHYTGWGRLSAKLINGIRDKESQKTILDYLISDGRANRNFMQLIHDDGLSFKPIIDKAQAGSHSDNLKEVVGELAGSPAIKKGILQSLKIVDELVKVMGYEPEQVVVEMARENQTTNQGRRNTRQRYKLLEEGVKNLASDLNGNILKEYPTDNQALQNERLFLYYLQNGRDMYTGEALDIDNLSQYDIDHIVPQAFIKDDSIDNRVLVSSAKNRGKSDNVPSIDIVKARKAFWKKLLDAKLMSQRKYDNLTKAERGGLTSDDKARFIQRQLVETRQITKHVARILDERFNNELDSKGRRIRKVKIVTLKSNLVSNFRKEFGFYKIREVNDYHHAHDAYLNAVVAKAILTKYPQLEPEFVYGDYPKYNSYKTRKSATEKLFFYSNIMNFFKTKVTLADGTVVVKDDIEVNNDTGEIVWDKKKHFATVRKVLSYPQVNIVKKTEIQTGGFSKESILAHGNSDKLIPRKTKDIYLDPKKYGGFDSPIVAYSVLVVADIKKGKAQKLKTVTELLGITIMERFRFEKNPSAFLESKGYLNIRDDKLMILPKYSLFELENGRRRLLASAGELQKGNELALPTQYMKFLYLASRYNELKGKPEEIEQKQEFVVQHVSYFDDILQIINDFSNRVILADANLEKINKLYQDNKENISVDELANNIINLFTFTSLGAPAAFKFFDKIVDRKRYTSTKEVLNSTLIHQSITGLYETRIDLGKLGED
>CP021773.1|AWZ37380.1|1090189_1090846_-|TIGR01906-family-membrane-protein
MKDKLLVVLTWIWIISLATLATIYIAWLIYPIEIQFLKLEKVVYLKAETIYYNFNKLMIYLTHPFISDLNMPSFPSSEDGLKHFADVKYLFTLAHGLFVILTFPVIYFLRRGWKQKSIFLYEGFFKIAIMLPIFIVVCAFLLGFDQFFTLFHEVLFPGDSTWQFNPLTDPVIWILPETFFLHCFIIFLLIYETITIILLIIGRKHLKLRKYKNKMQAL
>CP021773.1|AWZ36279.1|1090835_1091606_-|TIGR01457-family-HAD-type-hydrolase
MAYKGYLIDLDGTIYKGKSRIPAGERFIERLQEKGIPYMLVTNNTTRTPESVQEMLRGFNVETPLETIYTATMATVDYMNDMNRGKTAYVIGEEGLKKAIADAGYVEDTKNPAYVVVGLDWNVTYDKLATATLAIQNGALFIGTNPDLNIPTERGLLPGAGSLNALLEAATRIKPVFIGKPNAIIMNKALEILNIPRNQAVMVGDNYLTDIMAGINNDIDTLLVTTGFTTVEEVPDLPIQPSYVLASLDEWTFNEG
>CP021773.1|AWZ36280.1|1091606_1092344_-|acyl-[acyl-carrier-protein]-thioesterase
MGLLYRETYEVPFYESDTNHYMKLPQLLALALQISAKQSLKLGIGDDIVFKRYGLVWVVTDYIIDIERLPKHAEKIVIETEAKAHNKLLCYRYFYIYGEDGQKIITISSAFVLMDFKTRKIHPVLDDITSIYQSQRIKKVIRGPKYHPIGDSKVKQYHVRYFDLDMNGHVNNSKYLEWMYDVLDLDFLSSHIPKKIDLKYIKEIQYGTDIKSHWYQDGLVTRHDIIGGDAIHAQARIEWQEKKED
>CP021773.1|AWZ36281.1|1092347_1093478_-|coproporphyrinogen-III-oxidase
MLKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLQALIREFRSYDITELRTLYIGGGTPTSISAVQLDYLLTELSRDLNLNTLEEFTIEANPGDLTVDKIEVLQKSAVNRVSLGVQTFNDKHLKRIGRSHNEVQIYSTIDALKTAGFQNISIDLIYALPGQTMDDVRSNVAKALSLNIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEMFEYIISEMERNGFEHYEISNFTKPGFESRHNLMYWDNVEYYGVGAGASGYLDGIRYRNRGPIQHYLKGVSEGNARLSEEVLSKNEMMEEELFLGLRKKKGVSIGKFEQKFGTSFEKRYGQIVQELQSDGLLKENNGFIQMTKKGLFLGDTVAEKFIVE
>CP021773.1|AWZ36282.1|1093570_1093951_-|hypothetical-protein
MRLWHQDIIELLPRQQLLGQHRECCALRGNGWGRKHETVDYVFRYSPYRLFAYHQLVMEEMMERGYRVSKEWLIAEYRGMKCPRYDTLNPVDLETPIYPEHNQDYLQECLWNLKAKGIDLPINKIK
>CP021773.1|AWZ36283.1|1093975_1094347_-|hypothetical-protein
MTKEAELLWAKHKYLVLSKSQKIYLDIRQTLKSPNCTVLDVQSLIDQAVLLEESPSQVTNAYMHIWGYFKNKAERQEKEEFLTLLEKYRKTGYQRRKLLAFLKQLLAKYPNSYLQNSSIFEEE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP021773_1	1.2\|1083375\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	MK448971	Streptococcus phage Javan52, complete genome	25346-25375	0	1.0
CP021773_1	1.2\|1083375\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	MK448956	Streptococcus phage Javan48, complete genome	23665-23694	0	1.0
CP021773_1	1.3\|1083441\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448796	Streptococcus phage Javan53, complete genome	38135-38164	0	1.0
CP021773_1	1.3\|1083441\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448971	Streptococcus phage Javan52, complete genome	34320-34349	0	1.0
CP021773_1	1.3\|1083441\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448736	Streptococcus phage Javan35, complete genome	29484-29513	0	1.0
CP021773_1	1.3\|1083441\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448956	Streptococcus phage Javan48, complete genome	32639-32668	0	1.0
CP021773_1	1.3\|1083441\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448781	Streptococcus phage Javan5, complete genome	31506-31535	0	1.0
CP021773_1	1.3\|1083441\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448938	Streptococcus phage Javan44, complete genome	29485-29514	0	1.0
CP021773_1	1.3\|1083441\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448911	Streptococcus phage Javan34, complete genome	29484-29513	0	1.0
CP021773_1	1.3\|1083441\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448837	Streptococcus phage Javan10, complete genome	27542-27571	0	1.0
CP021773_1	1.3\|1083441\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083441-1083470	30	MK448916	Streptococcus phage Javan36, complete genome	29484-29513	0	1.0
CP021773_1	1.5\|1083573\|30\|CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	MH853356	Streptococcus phage LF2, partial genome	36955-36984	0	1.0
CP021773_1	1.8\|1083771\|30\|CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083771-1083800	30	MK448956	Streptococcus phage Javan48, complete genome	33978-34007	0	1.0
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448871	Streptococcus phage Javan196, complete genome	37399-37428	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448952	Streptococcus phage Javan472, complete genome	36830-36859	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448775	Streptococcus phage Javan489, complete genome	38943-38972	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448961	Streptococcus phage Javan494, complete genome	36338-36367	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448970	Streptococcus phage Javan516, complete genome	42552-42581	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448697	Streptococcus phage Javan185, complete genome	37399-37428	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448953	Streptococcus phage Javan474, complete genome	40664-40693	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448693	Streptococcus phage Javan177, complete genome	37399-37428	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448945	Streptococcus phage Javan454, complete genome	36499-36528	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448766	Streptococcus phage Javan465, complete genome	37195-37224	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448696	Streptococcus phage Javan183, complete genome	37399-37428	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448868	Streptococcus phage Javan188, complete genome	37400-37429	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448866	Streptococcus phage Javan184, complete genome	37399-37428	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448851	Streptococcus phage Javan14, complete genome	39043-39072	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448699	Streptococcus phage Javan189, complete genome	37399-37428	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448867	Streptococcus phage Javan186, complete genome	37399-37428	1	0.967
CP021773_1	1.5\|1083573\|30\|CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	MK448749	Streptococcus phage Javan39, complete genome	26022-26051	1	0.967
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448796	Streptococcus phage Javan53, complete genome	44973-45002	2	0.933
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MK448956	Streptococcus phage Javan48, complete genome	38085-38114	2	0.933
CP021773_1	1.5\|1083573\|30\|CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	MK448694	Streptococcus phage Javan179, complete genome	25046-25075	2	0.933
CP021773_1	1.5\|1083573\|30\|CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	JX409894	Streptococcus phage LYGO9, complete genome	22367-22396	3	0.9
CP021773_1	1.5\|1083573\|30\|CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	JX409895	Streptococcus phage JX01, complete genome	34214-34243	3	0.9
CP021773_1	1.4\|1083507\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	KT337358	Streptococcus phage phiARI0468-4, complete genome	28300-28329	4	0.867
CP021773_1	1.4\|1083507\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	NC_022791	Streptococcus phage phiBHN167 complete genome	23705-23734	4	0.867
CP021773_1	1.4\|1083507\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	MK448898	Streptococcus phage Javan284, complete genome	8520-8549	4	0.867
CP021773_1	1.4\|1083507\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	KY065502	Streptococcus phage IPP66, complete genome	7847-7876	4	0.867
CP021773_1	1.4\|1083507\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	MT900488	Streptococcus phage SA01, complete genome	8543-8572	4	0.867
CP021773_1	1.4\|1083507\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	AJ490330	Bacteriophage VO1 ORF1 and met gene for putative C5-methylase	736-765	4	0.867
CP021773_1	1.4\|1083507\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083507-1083536	30	KY065456	Streptococcus phage IPP15, complete genome	9104-9133	4	0.867
CP021773_1	1.2\|1083375\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	MK448851	Streptococcus phage Javan14, complete genome	24320-24349	5	0.833
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	NZ_CP014491	Escherichia coli strain G749 plasmid pG749_3, complete sequence	41416-41445	6	0.8
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	NC_041936	Escherichia phage ECD7, complete genome	82144-82173	6	0.8
CP021773_1	1.2\|1083375\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	NC_019691	Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence	26157-26186	6	0.8
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	NZ_CP024793	Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence	135471-135500	7	0.767
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	CP015514	Vibrio vulnificus strain FORC_036 plasmid unnamed, complete sequence	858564-858593	7	0.767
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	MG945249	UNVERIFIED: Microviridae sp. isolate 2447-1602, partial genome	2309-2338	7	0.767
CP021773_1	1.2\|1083375\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	MK448821	Streptococcus phage Javan623, complete genome	20349-20378	7	0.767
CP021773_1	1.2\|1083375\|30\|CP021773\|CRT,PILER-CR,CRISPRCasFinder	1083375-1083404	30	MK448822	Streptococcus phage Javan629, complete genome	23253-23282	7	0.767
CP021773_1	1.5\|1083573\|30\|CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	NZ_CP047439	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-2, complete sequence	37036-37065	7	0.767
CP021773_1	1.5\|1083573\|30\|CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	NZ_CP047440	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-3, complete sequence	62197-62226	7	0.767
CP021773_1	1.6\|1083639\|30\|CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083639-1083668	30	NZ_CP026738	Bacillus megaterium strain YC4-R4 plasmid unnamed2	132906-132935	7	0.767
CP021773_1	1.6\|1083639\|30\|CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083639-1083668	30	NC_014025	Bacillus megaterium QM B1551 plasmid pBM500, complete sequence	38202-38231	7	0.767
CP021773_1	1.7\|1083705\|30\|CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083705-1083734	30	NC_015937	Thermus phage TMA, complete genome	108316-108345	7	0.767
CP021773_1	1.7\|1083705\|30\|CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083705-1083734	30	MH595538	Vibrio phage BONAISHI, complete genome	251052-251081	7	0.767
CP021773_1	1.7\|1083705\|30\|CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083705-1083734	30	AP011617	Thermus phage TMA DNA, complete genome	108316-108345	7	0.767
CP021773_1	1.1\|1083309\|30\|CP021773\|CRT	1083309-1083338	30	NC_022883	Enterococcus mundtii QU 25 plasmid pQY082, complete sequence	57911-57940	8	0.733
CP021773_1	1.5\|1083573\|30\|CP021773\|CRT,CRISPRCasFinder	1083573-1083602	30	NZ_CP021745	Agarilytica rhodophyticola strain 017 plasmid pSU1, complete sequence	124621-124650	8	0.733
CP021773_2	2.2\|2212979\|30\|CP021773\|CRT	2212979-2213008	30	MN855875	Bacteriophage sp. isolate 328, complete genome	1401-1430	8	0.733
CP021773_1	1.8\|1083771\|30\|CP021773\|CRT,CRISPRCasFinder,PILER-CR	1083771-1083800	30	NZ_CP023038	Komagataeibacter saccharivorans strain CV1 plasmid unnamed2, complete sequence	114479-114508	9	0.7

1. spacer 1.2|1083375|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 0, identity: 1.0

tgccttttaattcagctcccactttttatc	CRISPR spacer
tgccttttaattcagctcccactttttatc	Protospacer
******************************

2. spacer 1.2|1083375|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

tgccttttaattcagctcccactttttatc	CRISPR spacer
tgccttttaattcagctcccactttttatc	Protospacer
******************************

3. spacer 1.3|1083441|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

4. spacer 1.3|1083441|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448971 (Streptococcus phage Javan52, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

5. spacer 1.3|1083441|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448736 (Streptococcus phage Javan35, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

6. spacer 1.3|1083441|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

7. spacer 1.3|1083441|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448781 (Streptococcus phage Javan5, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

8. spacer 1.3|1083441|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448938 (Streptococcus phage Javan44, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

9. spacer 1.3|1083441|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448911 (Streptococcus phage Javan34, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

10. spacer 1.3|1083441|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448837 (Streptococcus phage Javan10, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

11. spacer 1.3|1083441|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448916 (Streptococcus phage Javan36, complete genome) position: , mismatch: 0, identity: 1.0

cgatttgctcgtacattataaataccacca	CRISPR spacer
cgatttgctcgtacattataaataccacca	Protospacer
******************************

12. spacer 1.5|1083573|30|CP021773|CRT,CRISPRCasFinder matches to MH853356 (Streptococcus phage LF2, partial genome) position: , mismatch: 0, identity: 1.0

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tacctggaatgttaaatttaccttttagca	Protospacer
******************************

13. spacer 1.8|1083771|30|CP021773|CRT,CRISPRCasFinder,PILER-CR matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 0, identity: 1.0

tttacattaaaaaaatggacgagcggtcaa	CRISPR spacer
tttacattaaaaaaatggacgagcggtcaa	Protospacer
******************************

14. spacer 1.1|1083309|30|CP021773|CRT matches to MK448871 (Streptococcus phage Javan196, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

15. spacer 1.1|1083309|30|CP021773|CRT matches to MK448952 (Streptococcus phage Javan472, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

16. spacer 1.1|1083309|30|CP021773|CRT matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

17. spacer 1.1|1083309|30|CP021773|CRT matches to MK448961 (Streptococcus phage Javan494, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

18. spacer 1.1|1083309|30|CP021773|CRT matches to MK448970 (Streptococcus phage Javan516, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

19. spacer 1.1|1083309|30|CP021773|CRT matches to MK448697 (Streptococcus phage Javan185, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

20. spacer 1.1|1083309|30|CP021773|CRT matches to MK448953 (Streptococcus phage Javan474, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

21. spacer 1.1|1083309|30|CP021773|CRT matches to MK448693 (Streptococcus phage Javan177, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

22. spacer 1.1|1083309|30|CP021773|CRT matches to MK448945 (Streptococcus phage Javan454, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

23. spacer 1.1|1083309|30|CP021773|CRT matches to MK448766 (Streptococcus phage Javan465, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

24. spacer 1.1|1083309|30|CP021773|CRT matches to MK448696 (Streptococcus phage Javan183, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

25. spacer 1.1|1083309|30|CP021773|CRT matches to MK448868 (Streptococcus phage Javan188, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

26. spacer 1.1|1083309|30|CP021773|CRT matches to MK448866 (Streptococcus phage Javan184, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

27. spacer 1.1|1083309|30|CP021773|CRT matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

28. spacer 1.1|1083309|30|CP021773|CRT matches to MK448699 (Streptococcus phage Javan189, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

29. spacer 1.1|1083309|30|CP021773|CRT matches to MK448867 (Streptococcus phage Javan186, complete genome) position: , mismatch: 1, identity: 0.967

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaggaatataaaagtcgttcaaat	Protospacer
*******************.**********

30. spacer 1.5|1083573|30|CP021773|CRT,CRISPRCasFinder matches to MK448749 (Streptococcus phage Javan39, complete genome) position: , mismatch: 1, identity: 0.967

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tgcctggaatgttaaatttaccttttagca	Protospacer
*.****************************

31. spacer 1.1|1083309|30|CP021773|CRT matches to MK448796 (Streptococcus phage Javan53, complete genome) position: , mismatch: 2, identity: 0.933

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acataccaggaatataaaagtcgttcaaat	Protospacer
*****.*************.**********

32. spacer 1.1|1083309|30|CP021773|CRT matches to MK448956 (Streptococcus phage Javan48, complete genome) position: , mismatch: 2, identity: 0.933

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acataccaggaatataaaagtcgttcaaat	Protospacer
*****.*************.**********

33. spacer 1.5|1083573|30|CP021773|CRT,CRISPRCasFinder matches to MK448694 (Streptococcus phage Javan179, complete genome) position: , mismatch: 2, identity: 0.933

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tacccggaatgttaaacttaccttttagca	Protospacer
****.***********.*************

34. spacer 1.5|1083573|30|CP021773|CRT,CRISPRCasFinder matches to JX409894 (Streptococcus phage LYGO9, complete genome) position: , mismatch: 3, identity: 0.9

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tgccaggaatgttaaatttaccttttaaca	Protospacer
*.** **********************.**

35. spacer 1.5|1083573|30|CP021773|CRT,CRISPRCasFinder matches to JX409895 (Streptococcus phage JX01, complete genome) position: , mismatch: 3, identity: 0.9

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tgccaggaatgttaaatttaccttttaaca	Protospacer
*.** **********************.**

36. spacer 1.4|1083507|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to KT337358 (Streptococcus phage phiARI0468-4, complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

37. spacer 1.4|1083507|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to NC_022791 (Streptococcus phage phiBHN167 complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

38. spacer 1.4|1083507|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448898 (Streptococcus phage Javan284, complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgaaccgttaccgctatcgaaaa	Protospacer
* ******** **************.** *

39. spacer 1.4|1083507|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to KY065502 (Streptococcus phage IPP66, complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

40. spacer 1.4|1083507|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MT900488 (Streptococcus phage SA01, complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

41. spacer 1.4|1083507|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to AJ490330 (Bacteriophage VO1 ORF1 and met gene for putative C5-methylase) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

42. spacer 1.4|1083507|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to KY065456 (Streptococcus phage IPP15, complete genome) position: , mismatch: 4, identity: 0.867

ttgtatatgacccgttaccgctatcaaata	CRISPR spacer
tagtatatgagccgttaccactatcaaaca	Protospacer
* ******** ********.********.*

43. spacer 1.2|1083375|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448851 (Streptococcus phage Javan14, complete genome) position: , mismatch: 5, identity: 0.833

tgccttttaattcagctcccactttttatc	CRISPR spacer
ctccttttaattcagcacccattttttaac	Protospacer
. ************** ****.****** *

44. spacer 1.1|1083309|30|CP021773|CRT matches to NZ_CP014491 (Escherichia coli strain G749 plasmid pG749_3, complete sequence) position: , mismatch: 6, identity: 0.8

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
gcatatcaggaatataaaaatcataaagag	Protospacer
.*********************.*  *.*

45. spacer 1.1|1083309|30|CP021773|CRT matches to NC_041936 (Escherichia phage ECD7, complete genome) position: , mismatch: 6, identity: 0.8

acatatcaggaatataaaaatcgttcaaat-	CRISPR spacer
gcatatcaggaatattaaaattg-tcacctg	Protospacer
.************** *****.* ***  *

46. spacer 1.2|1083375|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to NC_019691 (Synechococcus sp. PCC 7502 plasmid pSYN7502.01, complete sequence) position: , mismatch: 6, identity: 0.8

tgccttttaattcagctcccactttttatc	CRISPR spacer
ctccttttaattcagcttccactttatcta	Protospacer
. ***************.******* * *

47. spacer 1.1|1083309|30|CP021773|CRT matches to NZ_CP024793 (Nostoc flagelliforme CCNUN1 plasmid pNFSY08, complete sequence) position: , mismatch: 7, identity: 0.767

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
gaatatcaggaatataaaaatttttcccaa	Protospacer
. *******************. ***  *

48. spacer 1.1|1083309|30|CP021773|CRT matches to CP015514 (Vibrio vulnificus strain FORC_036 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
ccagatcaggaatataaatatcgttacctt	Protospacer
 ** ************** ******    *

49. spacer 1.1|1083309|30|CP021773|CRT matches to MG945249 (UNVERIFIED: Microviridae sp. isolate 2447-1602, partial genome) position: , mismatch: 7, identity: 0.767

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
acatatcaagaatataaaaatcttgagcaa	Protospacer
********.************* *  . *

50. spacer 1.2|1083375|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448821 (Streptococcus phage Javan623, complete genome) position: , mismatch: 7, identity: 0.767

tgccttttaattcagctcccactttttatc	CRISPR spacer
tgccttttaattcagctcccatactaacta	Protospacer
*********************. .*   *

51. spacer 1.2|1083375|30|CP021773|CRT,PILER-CR,CRISPRCasFinder matches to MK448822 (Streptococcus phage Javan629, complete genome) position: , mismatch: 7, identity: 0.767

tgccttttaattcagctcccactttttatc	CRISPR spacer
tgccttttaattcagctcccatactaacta	Protospacer
*********************. .*   *

52. spacer 1.5|1083573|30|CP021773|CRT,CRISPRCasFinder matches to NZ_CP047439 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-2, complete sequence) position: , mismatch: 7, identity: 0.767

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tatttggaatgtttaatttatcttttactt	Protospacer
**..********* ******.****** .

53. spacer 1.5|1083573|30|CP021773|CRT,CRISPRCasFinder matches to NZ_CP047440 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-3, complete sequence) position: , mismatch: 7, identity: 0.767

tacctggaatgttaaatttaccttttagca	CRISPR spacer
tatttggaatgtttaatttatcttttactt	Protospacer
**..********* ******.****** .

54. spacer 1.6|1083639|30|CP021773|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP026738 (Bacillus megaterium strain YC4-R4 plasmid unnamed2) position: , mismatch: 7, identity: 0.767

atgttgccactagttgctctttatgaacag	CRISPR spacer
tcgctctgactagttgctctttatgaacaa	Protospacer
 .*.* . *********************.

55. spacer 1.6|1083639|30|CP021773|CRT,CRISPRCasFinder,PILER-CR matches to NC_014025 (Bacillus megaterium QM B1551 plasmid pBM500, complete sequence) position: , mismatch: 7, identity: 0.767

atgttgccactagttgctctttatgaacag	CRISPR spacer
tcgctctgactagttgctctttatgaacaa	Protospacer
 .*.* . *********************.

56. spacer 1.7|1083705|30|CP021773|CRT,CRISPRCasFinder,PILER-CR matches to NC_015937 (Thermus phage TMA, complete genome) position: , mismatch: 7, identity: 0.767

agtttcttttaagttcaatgtttgtcaaat----	CRISPR spacer
agtttcttttgagtttaatgttt----tattctg	Protospacer
**********.****.*******     **

57. spacer 1.7|1083705|30|CP021773|CRT,CRISPRCasFinder,PILER-CR matches to MH595538 (Vibrio phage BONAISHI, complete genome) position: , mismatch: 7, identity: 0.767

agtttcttttaagttcaatgtttgtcaaat	CRISPR spacer
tgtttcctttatgttcaatgtttgccttaa	Protospacer
 *****.**** ************.*  *

58. spacer 1.7|1083705|30|CP021773|CRT,CRISPRCasFinder,PILER-CR matches to AP011617 (Thermus phage TMA DNA, complete genome) position: , mismatch: 7, identity: 0.767

agtttcttttaagttcaatgtttgtcaaat----	CRISPR spacer
agtttcttttgagtttaatgttt----tattctg	Protospacer
**********.****.*******     **

59. spacer 1.1|1083309|30|CP021773|CRT matches to NC_022883 (Enterococcus mundtii QU 25 plasmid pQY082, complete sequence) position: , mismatch: 8, identity: 0.733

acatatcaggaatataaaaatcgttcaaat	CRISPR spacer
ccccttcaggaatatagaaatcattcaata	Protospacer
 * . ***********.*****.*****

60. spacer 1.5|1083573|30|CP021773|CRT,CRISPRCasFinder matches to NZ_CP021745 (Agarilytica rhodophyticola strain 017 plasmid pSU1, complete sequence) position: , mismatch: 8, identity: 0.733

tacctggaatgttaaatttaccttttagca	CRISPR spacer
cttggagaaggttaaatttaccttatagca	Protospacer
. .  .*** ************** *****

61. spacer 2.2|2212979|30|CP021773|CRT matches to MN855875 (Bacteriophage sp. isolate 328, complete genome) position: , mismatch: 8, identity: 0.733

ttaaaccagacgttaagccagaggccaaac	CRISPR spacer
atggcgcagacgttgagccagaggccactc	Protospacer
 *..  ********.************  *

62. spacer 1.8|1083771|30|CP021773|CRT,CRISPRCasFinder,PILER-CR matches to NZ_CP023038 (Komagataeibacter saccharivorans strain CV1 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

tttacattaaaaaaatggacgagcggtcaa	CRISPR spacer
gacagattaaaaaaatggccgagcggattg	Protospacer
  .* ************* ******* . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

373554 : 385050

Streptococcus_phage(90.91%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ35648.1\|373554_374265_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.2e-17	28.1
AWZ35649.1\|374283_374943_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	8.0e-65	56.0
AWZ35650.1\|375207_376374_-\|transposase	IS30 family transposase	NA	NA	NA	NA
AWZ35651.1\|376582_377218_+	thymidylate kinase	M1PSC7	Streptococcus_phage	2.8e-67	61.1
AWZ35652.1\|377237_378101_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	3.1e-72	49.0
AWZ35653.1\|378130_378457_+	initiation-control protein YabA	M1PFV3	Streptococcus_phage	3.2e-30	61.1
AWZ37350.1\|378462_379326_+	rRNA (cytidine-2'-O-)-methyltransferase	M1PLC5	Streptococcus_phage	3.7e-110	70.4
AWZ35654.1\|379301_379463_-	hypothetical protein	NA	NA	NA	NA
AWZ35655.1\|379447_379552_+	hypothetical protein	NA	NA	NA	NA
AWZ35656.1\|379595_380231_-	copper homeostasis protein CutC	NA	NA	NA	NA
AWZ35657.1\|380363_381455_+	phosphoserine transaminase	M1Q1P2	Streptococcus_phage	1.3e-163	77.1
AWZ35658.1\|381522_382071_+	acetyltransferase	M1PSC3	Streptococcus_phage	1.1e-54	58.4
AWZ35659.1\|383348_383825_+	cysteine methyltransferase	M1PFU9	Streptococcus_phage	7.1e-39	50.9
AWZ35660.1\|383826_384183_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	5.2e-42	72.6
AWZ35661.1\|384222_385050_-	exodeoxyribonuclease	M1PSC0	Streptococcus_phage	4.3e-124	78.0

DBSCAN-SWA_2

646321 : 708977

Streptococcus_phage(47.83%)

transposase,integrase,protease

attL 703502:703517|attR 712456:712471

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ35898.1\|646321_648430_-\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	4.8e-119	37.6
AWZ35899.1\|648862_649363_+	50S ribosomal protein L10	NA	NA	NA	NA
AWZ35900.1\|649426_649792_+	50S ribosomal protein L7/L12	NA	NA	NA	NA
AWZ37364.1\|650051_650225_+	hypothetical protein	NA	NA	NA	NA
AWZ35901.1\|650221_651046_+	replication initiator protein	A0A286QNA4	Streptococcus_phage	5.8e-12	37.6
AWZ35902.1\|651203_652559_+	DNA (cytosine-5-)-methyltransferase	A0A141E1L1	Streptococcus_phage	5.8e-126	55.9
AWZ35903.1\|652542_652971_+	hypothetical protein	NA	NA	NA	NA
AWZ35904.1\|652980_653364_+	hypothetical protein	NA	NA	NA	NA
AWZ35905.1\|653373_653607_+	transcriptional regulator	NA	NA	NA	NA
AWZ35906.1\|653609_654191_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AWZ35907.1\|654267_654756_+	hypothetical protein	NA	NA	NA	NA
AWZ35908.1\|654755_656576_+	conjugal transfer protein TraG	NA	NA	NA	NA
AWZ35909.1\|656593_656836_+	hypothetical protein	NA	NA	NA	NA
AWZ35910.1\|656852_657707_+	conjugal transfer protein TrbL	NA	NA	NA	NA
AWZ35911.1\|657768_658122_+	PrgI family protein	NA	NA	NA	NA
AWZ37365.1\|658099_660430_+	AAA family ATPase	NA	NA	NA	NA
AWZ35912.1\|660426_663231_+	CHAP domain-containing protein	NA	NA	NA	NA
AWZ35913.1\|663475_664069_+	hypothetical protein	NA	NA	NA	NA
AWZ35914.1\|664312_669217_+	glucan-binding protein	NA	NA	NA	NA
AWZ35915.1\|669217_669409_+	calcium-binding protein	NA	NA	NA	NA
AWZ35916.1\|669392_669944_+	hypothetical protein	NA	NA	NA	NA
AWZ35917.1\|669993_675453_+	hypothetical protein	A0A248SL14	Klebsiella_phage	8.2e-147	30.5
AWZ37366.1\|675950_677729_+	reverse transcriptase	A0A0U4J920	Pseudomonas_phage	8.9e-26	28.6
AWZ35918.1\|677866_679210_+	helicase	H2DE57	Erwinia_phage	2.1e-56	32.5
AWZ35919.1\|679279_679579_+	hypothetical protein	NA	NA	NA	NA
AWZ35920.1\|679593_679884_+	hypothetical protein	NA	NA	NA	NA
AWZ35921.1\|679994_680633_+	peptidylprolyl isomerase	NA	NA	NA	NA
AWZ35922.1\|680672_681761_+	DNA primase	NA	NA	NA	NA
AWZ35923.1\|681814_682030_+	hypothetical protein	NA	NA	NA	NA
AWZ35924.1\|682045_682441_+	chemotaxis protein	NA	NA	NA	NA
AWZ35925.1\|682484_682772_+	hypothetical protein	NA	NA	NA	NA
AWZ35926.1\|682798_683098_-	hypothetical protein	M1PG86	Streptococcus_phage	1.5e-26	59.6
AWZ35927.1\|683084_683453_-	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	3.7e-35	63.1
AWZ37367.1\|683449_684865_-	DNA polymerase	M1Q231	Streptococcus_phage	1.1e-215	78.1
AWZ35928.1\|685006_685699_-	XRE family transcriptional regulator	A0A1B0RXB1	Streptococcus_phage	6.0e-95	74.2
AWZ37368.1\|687722_688562_-\|transposase	transposase	A0A1P8CWQ3	Bacillus_phage	4.6e-49	41.1
AWZ35929.1\|688573_688834_-\|transposase	IS3 family transposase	A0A1P8CWP5	Bacillus_phage	1.7e-10	38.8
AWZ37369.1\|688864_689653_+	ATP-binding protein	A0A1B1IUG5	uncultured_Mediterranean_phage	3.4e-09	29.0
AWZ35930.1\|689852_690053_+	hypothetical protein	NA	NA	NA	NA
AWZ35931.1\|690071_690431_+	hypothetical protein	NA	NA	NA	NA
AWZ35932.1\|690440_690806_+	plasmid mobilization relaxosome protein MobC	NA	NA	NA	NA
AWZ35933.1\|690792_692655_+	relaxase	NA	NA	NA	NA
AWZ35934.1\|693435_693606_+	DNA recombinase	A0A1X9I6E4	Streptococcus_phage	3.7e-22	98.2
AWZ35935.1\|693991_695209_+	macrolide efflux MFS transporter Mef(A)	A0A2K5B2B5	Erysipelothrix_phage	5.1e-198	90.6
AWZ35936.1\|695328_696792_+	ABC-F type ribosomal protection protein Msr(D)	A0A1B0RXA0	Streptococcus_phage	3.7e-251	97.3
AWZ35937.1\|697194_697563_-	hypothetical protein	A0A1B0RXA8	Streptococcus_phage	1.1e-58	97.5
AWZ35938.1\|697575_697911_-	imsC-like protein	NA	NA	NA	NA
AWZ35939.1\|697907_698153_-	hypothetical protein	A0A1B0RXA7	Streptococcus_phage	2.6e-37	98.8
AWZ35940.1\|698149_698338_-	type VI secretion protein ImpB	Q6DMX4	Streptococcus_phage	1.5e-13	90.7
AWZ35941.1\|699117_699588_+	MarR family transcriptional regulator	NA	NA	NA	NA
AWZ35942.1\|699571_700597_+	aminoglycoside phosphotransferase	NA	NA	NA	NA
AWZ35943.1\|700593_702339_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.3e-37	25.6
AWZ35944.1\|702319_704059_+	ABC transporter ATP-binding protein	F2Y2R6	Organic_Lake_phycodnavirus	5.1e-18	28.1
703502:703517	attL	NA	NA	NA	NA
AWZ35945.1\|704170_704422_-\|transposase	transposase	NA	NA	NA	NA
AWZ35946.1\|704455_704950_+	peptidase	NA	NA	NA	NA
AWZ35947.1\|707031_707250_+	transcriptional regulator	A0A1L2BY72	Clostridium_phage	2.7e-09	52.5
AWZ35948.1\|707520_707769_+	hypothetical protein	NA	NA	NA	NA
AWZ35949.1\|707771_708977_+\|integrase	site-specific integrase	U3PJ31	Staphylococcus_phage	2.6e-08	21.4
712456:712471	attR	NA	NA	NA	NA

DBSCAN-SWA_3

717542 : 767381

Bacillus_phage(42.86%)

transposase,tRNA,integrase,tail

attL 712867:712883|attR 775903:775919

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
712867:712883	attL	NA	NA	NA	NA
AWZ35958.1\|717542_718745_+\|integrase	site-specific integrase	NA	NA	NA	NA
AWZ37370.1\|718924_720142_-	hypothetical protein	NA	NA	NA	NA
AWZ35959.1\|720284_721390_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	6.3e-70	48.9
AWZ35960.1\|722001_722379_+	chromosome partitioning protein ParA	NA	NA	NA	NA
AWZ35961.1\|722447_722678_+	hypothetical protein	NA	NA	NA	NA
AWZ35962.1\|722774_723323_+	hypothetical protein	NA	NA	NA	NA
AWZ35963.1\|723430_724765_+\|transposase	transposase	NA	NA	NA	NA
AWZ35964.1\|725418_728871_+	peptidase C5	A0A218KC60	Bacillus_phage	7.6e-05	39.4
AWZ37371.1\|729452_730730_+	group II intron reverse transcriptase/maturase	NA	NA	NA	NA
AWZ35965.1\|730963_731884_+	adhesion protein	NA	NA	NA	NA
AWZ35966.1\|731896_734365_+	histidine triad (HIT) protein	NA	NA	NA	NA
AWZ35967.1\|734563_734797_-	hypothetical protein	NA	NA	NA	NA
AWZ35968.1\|736198_737304_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	6.3e-70	48.9
AWZ35969.1\|737492_738089_-	hypothetical protein	NA	NA	NA	NA
AWZ35970.1\|738310_738808_+\|tail	phage tail protein	NA	NA	NA	NA
AWZ37372.1\|738817_739228_+	VOC family protein	NA	NA	NA	NA
AWZ35971.1\|739327_740668_+	MATE family efflux transporter	NA	NA	NA	NA
AWZ35972.1\|740726_741494_-	DNA integration/recombination/inversion protein	NA	NA	NA	NA
AWZ35973.1\|741652_743434_+	excinuclease ABC subunit C	NA	NA	NA	NA
AWZ35974.1\|743508_744853_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	7.4e-65	50.4
AWZ35975.1\|746861_747464_+	nitroreductase family protein	NA	NA	NA	NA
AWZ35976.1\|747510_748917_+	dipeptidase PepV	NA	NA	NA	NA
AWZ35977.1\|749013_749598_+	uracil-DNA glycosylase	NA	NA	NA	NA
AWZ35978.1\|749612_750347_+	hypothetical protein	NA	NA	NA	NA
AWZ35979.1\|750515_754274_+	pullulanase	NA	NA	NA	NA
AWZ35980.1\|755363_755540_-	DUF3042 domain-containing protein	NA	NA	NA	NA
AWZ35981.1\|755650_756541_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
AWZ35982.1\|756631_757870_+	GTPase HflX	NA	NA	NA	NA
AWZ35983.1\|757862_758510_+	cystathionine beta-lyase	NA	NA	NA	NA
AWZ35984.1\|758551_759481_+	ribonuclease Z	NA	NA	NA	NA
AWZ35985.1\|759482_760244_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
AWZ35986.1\|760240_762439_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.2e-72	29.1
AWZ35987.1\|762508_762607_+	hypothetical protein	NA	NA	NA	NA
AWZ35988.1\|762590_765155_+	hypothetical protein	NA	NA	NA	NA
AWZ35989.1\|765277_765796_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	4.6e-31	44.1
AWZ35990.1\|765913_766594_+	DNA replication protein DnaD	Q938N2	Temperate_phage	1.9e-08	31.8
AWZ35991.1\|766697_767381_+\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
775903:775919	attR	NA	NA	NA	NA

DBSCAN-SWA_4

1245265 : 1347227

Streptococcus_phage(70.0%)

terminase,transposase,tRNA,holin,head,portal,protease,tail,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ36413.1\|1245265_1245739_+\|tRNA	aminoacyl-tRNA deacylase	NA	NA	NA	NA
AWZ36414.1\|1245760_1246402_+	histidine phosphatase family protein	NA	NA	NA	NA
AWZ36415.1\|1246437_1247340_-	HAD family hydrolase	NA	NA	NA	NA
AWZ36416.1\|1247514_1249005_+\|tRNA	lysine--tRNA ligase	A0A1V0SAC0	Catovirus	7.6e-87	38.5
AWZ36417.1\|1249079_1249550_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.3e-40	52.7
AWZ36418.1\|1249564_1250758_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.5e-111	51.0
AWZ36419.1\|1250775_1251426_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	8.6e-35	39.9
AWZ36420.1\|1251406_1252516_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase	A0A1V0SE20	Indivirus	1.2e-55	37.2
AWZ36421.1\|1253243_1254584_+	divalent metal cation transporter	NA	NA	NA	NA
AWZ36422.1\|1254685_1255483_-	hypothetical protein	NA	NA	NA	NA
AWZ36423.1\|1255606_1255819_-	hypothetical protein	NA	NA	NA	NA
AWZ36424.1\|1255945_1257232_-\|protease	collagenase-like protease	Q6DW11	Phage_TP	1.9e-41	32.4
AWZ36425.1\|1257361_1258288_-	peptidase U32	NA	NA	NA	NA
AWZ36426.1\|1258630_1258906_+	hypothetical protein	NA	NA	NA	NA
AWZ36427.1\|1258946_1259378_-	YtxH domain-containing protein	NA	NA	NA	NA
AWZ36428.1\|1259374_1259773_-	DUF948 domain containing protein	NA	NA	NA	NA
AWZ36429.1\|1259787_1260561_-	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
AWZ36430.1\|1260553_1261489_-	HPr kinase/phosphorylase	NA	NA	NA	NA
AWZ36431.1\|1261604_1261739_-	hypothetical protein	NA	NA	NA	NA
AWZ36432.1\|1261716_1261980_-	phage shock protein C	NA	NA	NA	NA
AWZ37384.1\|1262060_1262489_-	M48 family peptidase	U5J9G1	Bacillus_phage	2.7e-05	26.2
AWZ37385.1\|1262481_1264644_-	RNA-binding transcriptional accessory protein	NA	NA	NA	NA
AWZ36433.1\|1264747_1265791_-	LLM class flavin-dependent oxidoreductase	NA	NA	NA	NA
AWZ36434.1\|1265923_1266052_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
AWZ36435.1\|1266057_1266960_+	ABC transporter permease	NA	NA	NA	NA
AWZ36436.1\|1266959_1267772_+	TIGR03943 family protein	NA	NA	NA	NA
AWZ36437.1\|1269664_1271242_-	signal recognition particle-docking protein FtsY	NA	NA	NA	NA
AWZ36438.1\|1271241_1272066_-	HAD family phosphatase	NA	NA	NA	NA
AWZ37386.1\|1272065_1272863_-	HAD family hydrolase	NA	NA	NA	NA
AWZ36439.1\|1272982_1274548_-	recombinase family protein	Q6DMS5	Streptococcus_phage	8.0e-180	61.5
AWZ36440.1\|1274550_1275759_-	recombinase family protein	Q6DMS6	Streptococcus_phage	1.8e-102	49.7
AWZ36441.1\|1275973_1276375_-	RNA polymerase subunit sigma-70	NA	NA	NA	NA
AWZ36442.1\|1276484_1277954_-	peptidoglycan-binding protein LysM	A0A1X9I678	Streptococcus_phage	1.8e-226	78.9
AWZ36443.1\|1277955_1278360_-\|holin	holin	D0R0E9	Streptococcus_phage	3.0e-46	74.8
AWZ36444.1\|1278377_1280234_-	hypothetical protein	Q6DMS9	Streptococcus_phage	2.5e-257	73.3
AWZ36445.1\|1280246_1283162_-	carbamoylsarcosine amidase	Q6DMT0	Streptococcus_phage	0.0e+00	64.8
AWZ36446.1\|1283161_1283887_-\|tail	phage tail protein	Q6DMT1	Streptococcus_phage	1.4e-81	57.9
AWZ36447.1\|1283883_1287003_-\|tail	phage tail tape measure protein	Q6DMT2	Streptococcus_phage	2.0e-254	76.7
AWZ36448.1\|1287185_1287605_-	hypothetical protein	A0A1X9I691	Streptococcus_phage	1.3e-55	76.3
AWZ36449.1\|1287616_1288186_-\|tail	phage tail protein	A0A1B0RXE2	Streptococcus_phage	1.5e-96	93.6
AWZ36450.1\|1288188_1288515_-	hypothetical protein	M1Q1Z4	Streptococcus_phage	8.3e-39	69.4
AWZ36451.1\|1288523_1288892_-	hypothetical protein	Q6DMT7	Streptococcus_phage	7.0e-34	62.9
AWZ36452.1\|1288884_1289223_-\|head,tail	head-tail adaptor protein	A0A1B0RXJ6	Streptococcus_phage	4.3e-38	70.5
AWZ36453.1\|1289222_1289480_-\|head,tail	phage gp6-like head-tail connector protein	D0R0D7	Streptococcus_phage	9.5e-30	78.8
AWZ36454.1\|1289476_1290685_-\|capsid	phage major capsid protein	E4ZFM5	Streptococcus_phage	1.0e-211	91.3
AWZ36455.1\|1290697_1291396_-	peptidase	A0A1B0RXE1	Streptococcus_phage	5.8e-106	83.6
AWZ36456.1\|1291388_1292684_-\|portal	phage portal protein	A0A1B0RXD8	Streptococcus_phage	8.0e-226	89.3
AWZ36457.1\|1292752_1292956_-	hypothetical protein	NA	NA	NA	NA
AWZ36458.1\|1293025_1293364_-	RelE/ParE family toxin	NA	NA	NA	NA
AWZ36459.1\|1293356_1293650_-	antitoxin	NA	NA	NA	NA
AWZ36460.1\|1293716_1295309_-\|terminase	terminase	A0A1B0RXJ8	Streptococcus_phage	6.0e-308	95.8
AWZ36461.1\|1295305_1295779_-\|terminase	terminase	A0A1X9I6K0	Streptococcus_phage	1.5e-84	96.8
AWZ36462.1\|1295827_1296277_-	DUF4314 domain-containing protein	A0A1X9I6A3	Streptococcus_phage	4.1e-20	67.1
AWZ36463.1\|1296278_1296530_-	hypothetical protein	M1PG57	Streptococcus_phage	5.8e-16	59.3
AWZ36464.1\|1296591_1297872_-	DNA (cytosine-5-)-methyltransferase	M1NSK8	Streptococcus_phage	2.2e-231	92.3
AWZ36465.1\|1297868_1299125_-	DNA modification methylase	A0A1B0RXE5	Streptococcus_phage	3.0e-225	90.9
AWZ36466.1\|1299096_1299552_-	hypothetical protein	M1Q209	Streptococcus_phage	1.0e-42	50.3
AWZ37387.1\|1299840_1300206_-	HNH endonuclease	A0A1B0RXJ3	Streptococcus_phage	3.2e-63	88.4
AWZ36467.1\|1301292_1301475_-	hypothetical protein	A0A1B0RXC3	Streptococcus_phage	1.7e-20	86.7
AWZ36468.1\|1301669_1302146_-	hypothetical protein	A0A1B0RXB9	Streptococcus_phage	3.2e-71	84.2
AWZ36469.1\|1302138_1303515_-	ATP-dependent helicase	A0A1X9I6B0	Streptococcus_phage	1.6e-232	86.7
AWZ36470.1\|1303495_1303777_-	nuclease	M1PFY8	Streptococcus_phage	1.1e-39	83.9
AWZ36471.1\|1304057_1306346_-	DNA primase	A0A1B0RXC5	Streptococcus_phage	0.0e+00	87.9
AWZ36472.1\|1306704_1307028_+	hypothetical protein	D0R0B4	Streptococcus_phage	8.8e-33	72.9
AWZ36473.1\|1307020_1308142_+	DUF2800 domain-containing protein	M1Q218	Streptococcus_phage	3.5e-201	90.9
AWZ36474.1\|1308146_1308710_+	hypothetical protein	A0A1B0RXA9	Streptococcus_phage	1.5e-91	92.8
AWZ37388.1\|1308944_1310900_+	hypothetical protein	E4ZFK1	Streptococcus_phage	0.0e+00	86.0
AWZ36475.1\|1310961_1311504_-	hypothetical protein	NA	NA	NA	NA
AWZ36476.1\|1311665_1312262_-	hypothetical protein	A0A1B0RXB3	Streptococcus_phage	4.6e-11	27.9
AWZ36477.1\|1312694_1313819_+	hypothetical protein	NA	NA	NA	NA
AWZ36478.1\|1313818_1314043_+	hypothetical protein	NA	NA	NA	NA
AWZ37389.1\|1314813_1315692_+	ATPase	NA	NA	NA	NA
AWZ36479.1\|1315681_1315891_+	transcriptional regulator	A0A2K5B263	Erysipelothrix_phage	4.8e-16	58.5
AWZ36480.1\|1316149_1316500_+\|transposase	transposase	NA	NA	NA	NA
AWZ36481.1\|1316553_1316739_+\|transposase	transposase	NA	NA	NA	NA
AWZ36482.1\|1316710_1317982_+\|transposase	transposase	NA	NA	NA	NA
AWZ36483.1\|1318262_1325591_-	hypothetical protein	NA	NA	NA	NA
AWZ36484.1\|1325824_1327075_+	YSIRK-targeted surface antigen transcriptional regulator	NA	NA	NA	NA
AWZ36485.1\|1327383_1328016_+	hypothetical protein	NA	NA	NA	NA
AWZ36486.1\|1328583_1329885_-	hypothetical protein	NA	NA	NA	NA
AWZ36487.1\|1330141_1330660_-	ClbS/DfsB family four-helix bundle protein	NA	NA	NA	NA
AWZ36488.1\|1331538_1335078_-	chromosome segregation protein SMC	NA	NA	NA	NA
AWZ36489.1\|1335085_1335772_-	ribonuclease 3	A0A167RGU4	Powai_lake_megavirus	3.3e-21	29.9
AWZ36490.1\|1335946_1336315_-	DUF454 domain-containing protein	NA	NA	NA	NA
AWZ36491.1\|1336317_1337127_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	2.5e-39	37.6
AWZ36492.1\|1337130_1338480_-	cell wall metabolism sensor histidine kinase VicK	W8CYF6	Bacillus_phage	2.7e-35	33.8
AWZ36493.1\|1338472_1339183_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	3.1e-38	38.5
AWZ36494.1\|1339522_1340278_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.6e-38	41.7
AWZ36495.1\|1340289_1341090_+	glutamine ABC transporter substrate-binding protein	NA	NA	NA	NA
AWZ36496.1\|1341102_1341798_+	amino acid ABC transporter permease	NA	NA	NA	NA
AWZ36497.1\|1341809_1342460_+	amino acid ABC transporter permease	NA	NA	NA	NA
AWZ36498.1\|1342508_1343075_-	peptidase	NA	NA	NA	NA
AWZ36499.1\|1343241_1344261_-	hypothetical protein	NA	NA	NA	NA
AWZ36500.1\|1344358_1345063_-	DNA-binding response regulator	W8CYM9	Bacillus_phage	1.3e-31	33.6
AWZ36501.1\|1345283_1347227_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	7.5e-119	37.9

DBSCAN-SWA_5

1434172 : 1446550

Streptococcus_phage(92.86%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ36575.1\|1434172_1435039_-	aminoglycoside 6-adenylyltransferase AadE	E4ZFP8	Streptococcus_phage	7.5e-103	63.7
AWZ36576.1\|1435214_1435760_-	hypothetical protein	NA	NA	NA	NA
AWZ36577.1\|1435811_1435970_-	zeta-toxin	NA	NA	NA	NA
AWZ36578.1\|1435971_1436244_-	antitoxin	A0A1X9I6E5	Streptococcus_phage	5.0e-05	100.0
AWZ36579.1\|1436261_1436477_-	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	4.2e-31	97.1
AWZ36580.1\|1436568_1437465_-	chromosome partitioning protein ParA	A0A1X9I765	Streptococcus_phage	1.9e-154	99.3
AWZ37395.1\|1437553_1437838_-	topoisomerase	A0A1X9I6W8	Streptococcus_phage	2.3e-40	93.0
AWZ36581.1\|1437847_1437979_-	hypothetical protein	E4ZFP9	Streptococcus_phage	8.2e-14	90.7
AWZ36582.1\|1437983_1438721_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
AWZ36583.1\|1438845_1438929_-	23S rRNA methyltransferase attenuator leader peptide ErmL	NA	NA	NA	NA
AWZ36584.1\|1439470_1440265_-	aminoglycoside O-phosphotransferase APH(3')-IIIa	E4ZFP6	Streptococcus_phage	2.3e-154	100.0
AWZ36585.1\|1440767_1441930_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	9.2e-80	53.7
AWZ36586.1\|1442003_1442210_-	streptothricin acetyltransferase	A0A1B0RXL7	Streptococcus_phage	4.8e-24	100.0
AWZ36587.1\|1442206_1443115_-	aminoglycoside nucleotidyltransferase ANT(6)-Ia	E4ZFP8	Streptococcus_phage	2.8e-177	100.0
AWZ36588.1\|1443147_1443882_-	methyltransferase	A0A1X9I6N4	Streptococcus_phage	1.5e-141	100.0
AWZ36589.1\|1443862_1444732_-	hypothetical protein	A0A1X9I6C9	Streptococcus_phage	6.7e-152	90.7
AWZ36590.1\|1444746_1444971_-	transcriptional regulator	NA	NA	NA	NA
AWZ36591.1\|1445470_1446550_+\|transposase	ISL3 family transposase	A0A1S5SBP9	Streptococcus_phage	1.6e-38	33.5

DBSCAN-SWA_6

1449782 : 1467874

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ37397.1\|1449782_1450361_-	DNA recombinase	A0A2K5B2B4	Erysipelothrix_phage	5.3e-20	31.4
AWZ36594.1\|1450428_1450887_+	hypothetical protein	NA	NA	NA	NA
AWZ37398.1\|1450937_1451189_-	hypothetical protein	NA	NA	NA	NA
AWZ36595.1\|1452346_1452874_-	adenine phosphoribosyltransferase	A0A1X9I6E2	Streptococcus_phage	1.9e-93	100.0
AWZ36596.1\|1452917_1453781_-	aminoglycoside nucleotidyltransferase ANT(6)-Ia	A0A1X9I6F2	Streptococcus_phage	8.7e-168	100.0
AWZ36597.1\|1453813_1454548_-	methyltransferase	A0A1X9I6N4	Streptococcus_phage	1.5e-141	100.0
AWZ36598.1\|1454528_1455398_-	hypothetical protein	A0A1X9I6C9	Streptococcus_phage	1.2e-153	92.0
AWZ36599.1\|1455412_1455637_-	transcriptional regulator	NA	NA	NA	NA
AWZ37399.1\|1455779_1457324_-	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	2.3e-256	88.7
AWZ36600.1\|1457343_1457760_-	recombinase	A0A2K5B2B3	Erysipelothrix_phage	1.2e-71	98.6
AWZ37400.1\|1457760_1458057_-	DNA recombinase	A0A2K5B2B2	Erysipelothrix_phage	4.6e-44	91.8
AWZ36601.1\|1459261_1459864_-	Pin-related site-specific recombinase/DNA invertase	A0A219YA40	Aeromonas_phage	5.7e-17	38.3
AWZ36602.1\|1460250_1460424_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	4.6e-28	100.0
AWZ36603.1\|1460475_1462395_-	tetracycline resistance ribosomal protection protein Tet(O)	A0A1B0RXH7	Streptococcus_phage	0.0e+00	99.7
AWZ36604.1\|1462761_1463136_-	TnpV protein	D0R0F4	Streptococcus_phage	1.3e-67	99.2
AWZ36605.1\|1463940_1464231_-	hypothetical protein	NA	NA	NA	NA
AWZ36606.1\|1464244_1464544_-	hypothetical protein	NA	NA	NA	NA
AWZ36607.1\|1464614_1465958_-	ATP-dependent helicase	H2DE57	Erwinia_phage	8.2e-56	31.6
AWZ37401.1\|1466095_1467874_-	reverse transcriptase	A0A0U4J920	Pseudomonas_phage	8.9e-26	28.6

DBSCAN-SWA_7

1793873 : 1846116

Paramecium_bursaria_Chlorella_virus(12.5%)

transposase,tRNA,holin,integrase,bacteriocin

attL 1837608:1837624|attR 1841184:1841200

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ36902.1\|1793873_1794179_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AWZ36903.1\|1794390_1796376_-	transketolase	NA	NA	NA	NA
AWZ36904.1\|1796500_1797931_-	trans-acting positive regulator	NA	NA	NA	NA
AWZ36905.1\|1797921_1799259_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
AWZ36906.1\|1799346_1800045_-	aquaporin family protein	M1HWZ0	Paramecium_bursaria_Chlorella_virus	3.9e-33	35.9
AWZ36907.1\|1800056_1801886_-	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
AWZ36908.1\|1801898_1803407_-	glycerol kinase	NA	NA	NA	NA
AWZ36909.1\|1803521_1803785_-	hypothetical protein	NA	NA	NA	NA
AWZ36910.1\|1803873_1804131_-	hypothetical protein	NA	NA	NA	NA
AWZ36911.1\|1804142_1806182_-\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
AWZ36912.1\|1806185_1806827_-	FMN-dependent NADH-azoreductase	NA	NA	NA	NA
AWZ36913.1\|1806826_1807741_-\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
AWZ36914.1\|1808053_1808596_-	hypothetical protein	NA	NA	NA	NA
AWZ36915.1\|1808713_1809862_-	N-acetylglucosamine-6-phosphate deacetylase	NA	NA	NA	NA
AWZ36916.1\|1810139_1810847_-	peptidase	NA	NA	NA	NA
AWZ36917.1\|1811037_1811349_+	PadR family transcriptional regulator	NA	NA	NA	NA
AWZ37409.1\|1811525_1812053_+	hypothetical protein	NA	NA	NA	NA
AWZ36918.1\|1812316_1813033_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.2e-26	32.0
AWZ36919.1\|1813035_1814133_+	ABC transporter permease	NA	NA	NA	NA
AWZ36920.1\|1814156_1814765_+	TetR family transcriptional regulator	NA	NA	NA	NA
AWZ36921.1\|1814899_1815061_-	lipoprotein	NA	NA	NA	NA
AWZ36922.1\|1815344_1815836_+	RNA polymerase sigma factor	NA	NA	NA	NA
AWZ36923.1\|1815832_1816780_+	hypothetical protein	NA	NA	NA	NA
AWZ37410.1\|1817039_1817720_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AWZ36924.1\|1818445_1819006_-	acetyltransferase	NA	NA	NA	NA
AWZ36925.1\|1819453_1819804_-	hypothetical protein	NA	NA	NA	NA
AWZ36926.1\|1819813_1820086_-	hypothetical protein	NA	NA	NA	NA
AWZ36927.1\|1820104_1821739_-	hypothetical protein	NA	NA	NA	NA
AWZ36928.1\|1821802_1822261_-	hypothetical protein	NA	NA	NA	NA
AWZ36929.1\|1828946_1830092_+	glycine/betaine ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	1.9e-13	31.7
AWZ36930.1\|1830091_1830727_+\|holin	choline ABC transporter permease	NA	NA	NA	NA
AWZ36931.1\|1830729_1831656_+	osmoprotectant ABC transporter substrate-binding protein	NA	NA	NA	NA
AWZ37411.1\|1831665_1832307_+	amino acid ABC transporter permease	NA	NA	NA	NA
AWZ36932.1\|1832368_1833550_-	MFS transporter	NA	NA	NA	NA
AWZ37412.1\|1833622_1834246_-	MutR family transcriptional regulator	NA	NA	NA	NA
AWZ36933.1\|1834254_1834476_-	transcriptional regulator	NA	NA	NA	NA
AWZ36934.1\|1834475_1834601_-	hypothetical protein	NA	NA	NA	NA
AWZ36935.1\|1834597_1834702_-	hypothetical protein	NA	NA	NA	NA
AWZ36936.1\|1835338_1836775_-	ATP-dependent DNA helicase	A0A1B3AYT3	Gordonia_phage	9.3e-66	34.8
AWZ36937.1\|1836816_1837503_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	4.1e-128	100.0
1837608:1837624	attL	NA	NA	NA	NA
AWZ37413.1\|1838262_1838793_-	restriction endonuclease	A0A1V0SLK8	Klosneuvirus	1.1e-16	34.6
AWZ36938.1\|1838875_1839673_-\|integrase	integrase	A0A0H4TI16	Erysipelothrix_phage	1.2e-19	29.2
AWZ36939.1\|1839721_1841254_-	type I restriction endonuclease	NA	NA	NA	NA
1841184:1841200	attR	NA	NA	NA	NA
AWZ36940.1\|1841253_1842717_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
AWZ36941.1\|1842729_1845054_-	restriction endonuclease subunit R	Q5YA94	Bacillus_phage	6.4e-24	28.2
AWZ36942.1\|1845397_1845754_-\|transposase	transposase	NA	NA	NA	NA
AWZ36943.1\|1845750_1846116_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_8

2033643 : 2045707

Streptomyces_phage(14.29%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ37124.1\|2033643_2034948_-	peptigoglycan-binding protein LysM	A0A2D1GNZ3	Streptomyces_phage	1.7e-05	40.5
AWZ37125.1\|2035094_2035994_-	zoocin A	A0A221J6U0	Arthrobacter_phage	4.1e-19	45.9
AWZ37126.1\|2036186_2037734_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.5e-77	48.9
AWZ37127.1\|2037753_2038506_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
AWZ37128.1\|2038528_2039077_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.0e-25	35.6
AWZ37129.1\|2039243_2040266_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	2.0e-62	42.7
AWZ37130.1\|2040293_2041748_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.7e-54	32.7
AWZ37131.1\|2041981_2045707_-	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	4.3e-38	26.0

DBSCAN-SWA_9

2121230 : 2137401

Streptococcus_phage(71.43%)

integrase

attL 2123809:2123828|attR 2138216:2138235

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWZ37188.1\|2121230_2122586_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.2e-152	62.6
AWZ37189.1\|2122597_2122885_+	hypothetical protein	NA	NA	NA	NA
AWZ37190.1\|2123214_2123826_+	30S ribosomal protein S4	NA	NA	NA	NA
2123809:2123828	attL	NA	NA	NA	NA
AWZ37191.1\|2123932_2125105_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	5.7e-154	70.1
AWZ37192.1\|2125436_2126402_-	hypothetical protein	A0A0N9RUA4	Staphylococcus_phage	7.1e-86	51.1
AWZ37193.1\|2126428_2126770_-	hypothetical protein	A0A1S5SDB5	Streptococcus_phage	2.2e-13	59.7
AWZ37194.1\|2126781_2126967_-	hypothetical protein	NA	NA	NA	NA
AWZ37195.1\|2127480_2127768_-	hypothetical protein	A0A286QMZ8	Streptococcus_phage	1.9e-10	61.4
AWZ37196.1\|2127779_2128394_-	transcriptional regulator	A0A1X9I723	Streptococcus_phage	2.6e-17	68.7
AWZ37197.1\|2128599_2128800_+	transcriptional regulator	NA	NA	NA	NA
AWZ37198.1\|2128823_2129444_+	phage repressor protein	A0A1W6JPC3	Staphylococcus_phage	2.2e-40	43.8
AWZ37199.1\|2129443_2129713_+	phage antirepressor protein	NA	NA	NA	NA
AWZ37200.1\|2129935_2130574_+	hypothetical protein	NA	NA	NA	NA
AWZ37201.1\|2130672_2130846_+	CopG family transcriptional regulator	NA	NA	NA	NA
AWZ37202.1\|2130934_2131441_+	hypothetical protein	A0A1X9I5V7	Streptococcus_phage	2.2e-06	34.4
AWZ37203.1\|2131529_2131862_+	hypothetical protein	NA	NA	NA	NA
AWZ37423.1\|2131861_2132053_+	hypothetical protein	NA	NA	NA	NA
AWZ37204.1\|2132064_2132427_+	hypothetical protein	NA	NA	NA	NA
AWZ37205.1\|2132423_2132765_+	hypothetical protein	NA	NA	NA	NA
AWZ37206.1\|2132757_2133030_+	transcriptional regulator	A0A1X9I5U9	Streptococcus_phage	2.5e-28	69.8
AWZ37424.1\|2133198_2134020_+	DNA replication protein DnaD	R9QM95	Lactococcus_phage	1.2e-30	68.7
AWZ37207.1\|2134100_2134706_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.4e-39	47.3
AWZ37208.1\|2134790_2135279_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	7.3e-47	56.2
AWZ37209.1\|2135474_2135654_+	hypothetical protein	NA	NA	NA	NA
AWZ37210.1\|2135677_2136040_+	hypothetical protein	NA	NA	NA	NA
AWZ37211.1\|2136014_2136401_+	ArpU family transcriptional regulator	A0A141E173	Streptococcus_phage	1.8e-08	32.8
AWZ37212.1\|2136894_2137401_+	hypothetical protein	D7RWK7	Brochothrix_phage	3.0e-35	48.8
2138216:2138235	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage