CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
CP028484	Escherichia coli strain E41-1 plasmid p1, complete sequence	0 crisprs	RT	0	2
CP028483	Escherichia coli strain E41-1 chromosome, complete genome	3 crisprs	c2c9_V-U4,csa3,cas3,DEDDh,RT,DinG	4	9
CP028485	Escherichia coli strain E41-1 plasmid p2, complete sequence	0 crisprs	NA	0	0
CP028486	Escherichia coli strain E41-1 plasmid p3, complete sequence	0 crisprs	RT	0	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

889 : 29122

Escherichia_phage(44.44%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWR76669.1\|889_2503_+\|transposase	IS66 family transposase ISEc23	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
AWR76796.1\|2938_3073_+	type I toxin-antitoxin system hok family toxin	NA	NA	NA	NA
AWR76670.1\|3369_3624_+	replication protein	NA	NA	NA	NA
AWR76671.1\|3666_3777_-	replication protein RepA	NA	NA	NA	NA
AWR76797.1\|3860_3935_+	RepA leader peptide Tap	NA	NA	NA	NA
AWR76672.1\|3915_4785_+	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
AWR76673.1\|5724_6378_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
AWR76674.1\|6597_7062_+	mRNA interferase PemK	NA	NA	NA	NA
AWR76675.1\|7058_7163_+	hypothetical protein	NA	NA	NA	NA
AWR76676.1\|7346_8657_+	DUF262 domain-containing protein	NA	NA	NA	NA
AWR76677.1\|8933_9794_-	class A broad-spectrum beta-lactamase TEM-1	Q1MVP3	Enterobacteria_phage	4.6e-161	100.0
AWR76678.1\|10154_10859_+\|transposase	IS6 family transposase IS15DI	A0A077SL39	Escherichia_phage	1.2e-138	99.6
AWR76679.1\|11426_12287_+	EamA family transporter	NA	NA	NA	NA
AWR76680.1\|12318_13518_-	tetracycline efflux MFS transporter Tet(A)	NA	NA	NA	NA
AWR76681.1\|13596_14250_+	TetR family transcriptional regulator	NA	NA	NA	NA
AWR76798.1\|14281_14518_-	relaxase	NA	NA	NA	NA
AWR76682.1\|14571_15408_-	aminoglycoside O-phosphotransferase APH(6)-Id	NA	NA	NA	NA
AWR76683.1\|15407_16211_-	aminoglycoside O-phosphotransferase APH(3'')-Ib	NA	NA	NA	NA
AWR76684.1\|16271_17087_-	sulfonamide-resistant dihydropteroate synthase Sul2	A0A0B5J4J5	Pandoravirus	5.9e-09	27.6
AWR76685.1\|17394_17607_-	replication C family protein	NA	NA	NA	NA
AWR76686.1\|17631_18336_+\|transposase	IS6 family transposase IS15DIV	A0A077SL39	Escherichia_phage	1.8e-139	100.0
AWR76687.1\|18457_19363_+	Mph(A) family macrolide 2'-phosphotransferase	NA	NA	NA	NA
AWR76688.1\|19359_20598_+	MFS transporter	NA	NA	NA	NA
AWR76689.1\|20597_21182_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
AWR76690.1\|21127_21484_+	hypothetical protein	NA	NA	NA	NA
AWR76799.1\|21674_22439_-\|transposase	IS6 family transposase IS6100	A0A077SL39	Escherichia_phage	4.3e-86	65.7
AWR76691.1\|22467_22650_+	resolvase	NA	NA	NA	NA
AWR76692.1\|22665_22971_-	PadR family transcriptional regulator	NA	NA	NA	NA
AWR76693.1\|22981_24187_-	chromate transporter	NA	NA	NA	NA
AWR76694.1\|24342_24546_-	hypothetical protein	NA	NA	NA	NA
AWR76695.1\|24564_24744_+	hypothetical protein	NA	NA	NA	NA
AWR76696.1\|24673_25513_-	sulfonamide-resistant dihydropteroate synthase Sul1	A0A0B5J4J5	Pandoravirus	5.0e-11	27.2
AWR76697.1\|25506_25854_-	quaternary ammonium compound efflux SMR transporter QacE delta 1	NA	NA	NA	NA
AWR76698.1\|26059_26848_-	ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA5	NA	NA	NA	NA
AWR76800.1\|26978_27452_-	trimethoprim-resistant dihydrofolate reductase DfrA17	A0A1B2IAU3	Erwinia_phage	1.3e-16	34.6
AWR76699.1\|28417_29122_+\|transposase	IS6 family transposase IS15DI	A0A077SL39	Escherichia_phage	1.2e-138	99.6

DBSCAN-SWA_2

57685 : 108635

Escherichia_phage(33.33%)

integrase,transposase

attL 83763:83779|attR 101545:101561

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWR76731.1\|57685_58708_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	3.2e-201	99.7
AWR76732.1\|58704_59487_+\|transposase	transposase	A0A2L1IVB6	Escherichia_phage	2.0e-139	100.0
AWR76733.1\|60225_61017_-	DUF4198 domain-containing protein	NA	NA	NA	NA
AWR76734.1\|61023_62994_-	TonB-dependent hemoglobin/transferrin/lactoferrin family receptor	NA	NA	NA	NA
AWR76735.1\|64236_64509_+	transcriptional regulator	NA	NA	NA	NA
AWR76736.1\|65355_66525_-	hypothetical protein	NA	NA	NA	NA
AWR76737.1\|66891_67080_+	serine/threonine protein kinase	NA	NA	NA	NA
AWR76738.1\|67200_67941_+	site-specific recombinase	I3WFA4	Macacine_betaherpesvirus	1.6e-24	57.6
AWR76739.1\|68225_69203_-	repFIB replication protein A	J9Q7H0	Salmonella_phage	1.4e-100	59.2
AWR76740.1\|72545_73478_-	homocysteine S-methyltransferase	NA	NA	NA	NA
AWR76801.1\|73464_74868_-	S-methylmethionine permease	NA	NA	NA	NA
AWR76741.1\|75075_76092_+\|transposase	IS5-like element IS5 family transposase	Q38213	Escherichia_phage	4.9e-186	99.4
AWR76742.1\|76319_76637_+	type I deoxyribonuclease HsdR	NA	NA	NA	NA
AWR76743.1\|76923_77283_-	pdcB	A0A077SLM1	Escherichia_phage	5.0e-45	98.9
AWR76744.1\|77310_77490_-	PdcA protein	Q71TH5	Escherichia_phage	3.5e-23	96.6
AWR76745.1\|77494_77875_-	type II toxin-antitoxin system death-on-curing family toxin	A0A077SK56	Escherichia_phage	1.1e-63	100.0
AWR76746.1\|77874_78096_-	type II toxin-antitoxin system prevent-host-death family antitoxin	A0A222YXU1	Escherichia_phage	6.7e-32	100.0
AWR76802.1\|78278_79835_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	3.2e-104	42.7
AWR76747.1\|79831_81115_+	restriction endonuclease subunit S	F2Y1N5	Organic_Lake_phycodnavirus	2.2e-10	26.5
AWR76748.1\|83438_84371_-	hypothetical protein	NA	NA	NA	NA
83763:83779	attL	NA	NA	NA	NA
AWR76749.1\|84597_85745_-\|transposase	IS3-like element ISEc52 family transposase	Q716C2	Shigella_phage	7.0e-173	95.9
AWR76750.1\|85801_86623_-	nucleotidyltransferase	NA	NA	NA	NA
AWR76751.1\|87330_87549_+	antitoxin CcdA	NA	NA	NA	NA
AWR76752.1\|87550_87856_+	toxin CcdB	NA	NA	NA	NA
AWR76753.1\|87856_88663_+\|integrase	phage integrase family protein	I3WFA4	Macacine_betaherpesvirus	5.8e-57	100.0
AWR76754.1\|89436_90192_+	replication initiation protein	I3WF20	Macacine_betaherpesvirus	3.8e-143	100.0
AWR76755.1\|90779_91946_+	protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	7.0e-229	100.0
AWR76756.1\|91945_92917_+	ParB/RepB/Spo0J family partition protein	I3WF22	Macacine_betaherpesvirus	7.0e-174	99.4
AWR76757.1\|93473_93746_+	hypothetical protein	NA	NA	NA	NA
AWR76803.1\|93783_94686_+	DUF1281 domain-containing protein	NA	NA	NA	NA
AWR76758.1\|95070_95754_+	DNA methylase	A0A2I7RE86	Vibrio_phage	5.1e-30	36.9
AWR76759.1\|95754_95976_+	hypothetical protein	NA	NA	NA	NA
AWR76760.1\|95989_96424_+	DUF1380 domain-containing protein	NA	NA	NA	NA
AWR76761.1\|97123_97696_+	DUF1472 domain-containing protein	NA	NA	NA	NA
AWR76762.1\|97668_98094_+	antirestriction protein	NA	NA	NA	NA
AWR76763.1\|98140_98563_+	DUF1380 domain-containing protein	NA	NA	NA	NA
AWR76764.1\|98559_98751_+	hypothetical protein	NA	NA	NA	NA
AWR76765.1\|98683_98950_+	transporter	NA	NA	NA	NA
AWR76766.1\|99102_99525_-	hypothetical protein	NA	NA	NA	NA
AWR76767.1\|99785_100016_+	hypothetical protein	NA	NA	NA	NA
AWR76768.1\|100067_101429_+	DUF3560 domain-containing protein	NA	NA	NA	NA
AWR76769.1\|101476_102040_+	class I SAM-dependent methyltransferase	A8HNV9	Thalassomonas_phage	1.0e-20	37.3
101545:101561	attR	NA	NA	NA	NA
AWR76770.1\|102065_102314_+	hypothetical protein	NA	NA	NA	NA
AWR76804.1\|102534_102723_+	hypothetical protein	NA	NA	NA	NA
AWR76771.1\|102724_102931_+	single-stranded DNA-binding protein	NA	NA	NA	NA
AWR76772.1\|102956_103496_+	single-stranded DNA-binding protein	I3PGW4	Xanthomonas_phage	1.2e-45	73.9
AWR76773.1\|103558_103792_+	DUF905 domain-containing protein	NA	NA	NA	NA
AWR76774.1\|103857_105816_+	hypothetical protein	G8DH78	Emiliania_huxleyi_virus	1.3e-22	27.4
AWR76775.1\|105870_106305_+	conjugation system SOS inhibitor PsiB	NA	NA	NA	NA
AWR76776.1\|106301_107021_+	plasmid SOS inhibition protein A	NA	NA	NA	NA
AWR76777.1\|107266_108635_+\|transposase	IS3-like element IS150 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	1.3e-112	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP028483

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CRISPR-Cas detection and classification

Crispr_ID: CP028483_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028483_1

2345019-2345142

Orphan

Consensus_repeat	Method
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028483_1

>merge|CP028483|1|2345019-2345142|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTACGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAACGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

>CP028483|1|1|2345019-2345142|CRISPRCasFinder
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA	CGGACGCAGGATGGTGCGTTCAATTGGACTCGAACCAA
CGACCCCCACCATGTCAAGGTGGTGCTCTAACCAACTGAGCTA

Protein	Signature genes	Signature genes Name	Protein_function
CP028483.1\|AWR73947.1\|2344577_2344883_-\|monooxygenase	unknown	unknown	gnl\|CDD\|182975
CP028483.1\|AWR76553.1\|2340569_2341238_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
CP028483.1\|AWR73956.1\|2354038_2354128_+\|YnhF-family-membrane-protein	unknown	unknown	unknown
CP028483.1\|AWR73951.1\|2349022_2350171_-\|cyclopropane-fatty-acyl-phospholipid-synthase	unknown	unknown	gnl\|CDD\|183282
CP028483.1\|AWR73954.1\|2352714_2353740_-\|PurR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|236739
CP028483.1\|AWR73952.1\|2350461_2351673_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	unknown	unknown	gnl\|CDD\|182924
CP028483.1\|AWR73949.1\|2346753_2348127_-\|multidrug-resistance-protein-MdtK	unknown	unknown	gnl\|CDD\|234981
CP028483.1\|AWR73946.1\|2342847_2344452_-\|FAD-NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|182134
CP028483.1\|AWR73944.1\|2341234_2342020_+\|thiosulfate-reductase-cytochrome-B-subunit	unknown	unknown	gnl\|CDD\|184968
CP028483.1\|AWR73943.1\|2339858_2340506_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182160
CP028483.1\|AWR73941.1\|2337105_2337732_+\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|182135
CP028483.1\|AWR73953.1\|2351785_2352718_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182948
CP028483.1\|AWR73950.1\|2348341_2348983_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|183846
CP028483.1\|AWR73948.1\|2345456_2346713_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|137602
CP028483.1\|AWR73955.1\|2353727_2353952_-\|hypothetical-protein	unknown	unknown	unknown
CP028483.1\|AWR73957.1\|2354293_2355463_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
CP028483.1\|AWR73945.1\|2342023_2342836_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182159
CP028483.1\|AWR73942.1\|2337752_2339855_+\|aldehyde-ferredoxin-oxidoreductase	unknown	unknown	gnl\|CDD\|236629
CP028483.1\|AWR73940.1\|2336440_2336650_+\|fumarate-hydratase-FumD	unknown	unknown	gnl\|CDD\|182359
CP028483.1\|AWR73939.1\|2334471_2335884_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|181699

Protein	Function_ID	Function_description	E-value
CP028483.1\|AWR73947.1\|2344577_2344883_-\|monooxygenase	gnl\|CDD\|182975	PRK11118, PRK11118, putative monooxygenase; Provisional.	7.08279e-64
CP028483.1\|AWR76553.1\|2340569_2341238_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	3.44535e-77
CP028483.1\|AWR73951.1\|2349022_2350171_-\|cyclopropane-fatty-acyl-phospholipid-synthase	gnl\|CDD\|183282	PRK11705, PRK11705, cyclopropane fatty acyl phospholipid synthase.	0
CP028483.1\|AWR73954.1\|2352714_2353740_-\|PurR-family-transcriptional-regulator	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
CP028483.1\|AWR73952.1\|2350461_2351673_-\|Bcr/CflA-family-multidrug-efflux-MFS-transporter	gnl\|CDD\|182924	PRK11043, PRK11043, Bcr/CflA family multidrug efflux MFS transporter.	0
CP028483.1\|AWR73949.1\|2346753_2348127_-\|multidrug-resistance-protein-MdtK	gnl\|CDD\|234981	PRK01766, PRK01766, multidrug efflux protein; Reviewed.	0
CP028483.1\|AWR73946.1\|2342847_2344452_-\|FAD-NAD(P)-binding-protein	gnl\|CDD\|182134	PRK09897, PRK09897, FAD-NAD(P)-binding protein.	0
CP028483.1\|AWR73944.1\|2341234_2342020_+\|thiosulfate-reductase-cytochrome-B-subunit	gnl\|CDD\|184968	PRK15006, PRK15006, thiosulfate reductase cytochrome B subunit; Provisional.	4.53331e-162
CP028483.1\|AWR73943.1\|2339858_2340506_+\|hypothetical-protein	gnl\|CDD\|182160	PRK09947, PRK09947, YdhW family putative oxidoreductase system protein.	8.66973e-123
CP028483.1\|AWR73941.1\|2337105_2337732_+\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|182135	PRK09898, PRK09898, ferredoxin-like protein.	4.70639e-138
CP028483.1\|AWR73953.1\|2351785_2352718_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|182948	PRK11074, PRK11074, putative DNA-binding transcriptional regulator; Provisional.	0
CP028483.1\|AWR73950.1\|2348341_2348983_+\|riboflavin-synthase	gnl\|CDD\|183846	PRK13020, PRK13020, riboflavin synthase subunit alpha; Provisional.	2.24506e-123
CP028483.1\|AWR73948.1\|2345456_2346713_+\|hypothetical-protein	gnl\|CDD\|137602	PRK09945, PRK09945, hypothetical protein; Provisional.	0
CP028483.1\|AWR73957.1\|2354293_2355463_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	3.86098e-98
CP028483.1\|AWR73945.1\|2342023_2342836_+\|hypothetical-protein	gnl\|CDD\|182159	PRK09946, PRK09946, hypothetical protein; Provisional.	2.89827e-172
CP028483.1\|AWR73942.1\|2337752_2339855_+\|aldehyde-ferredoxin-oxidoreductase	gnl\|CDD\|236629	PRK09849, PRK09849, putative oxidoreductase; Provisional.	0
CP028483.1\|AWR73940.1\|2336440_2336650_+\|fumarate-hydratase-FumD	gnl\|CDD\|182359	PRK10292, PRK10292, fumarate hydratase FumD.	2.11502e-34
CP028483.1\|AWR73939.1\|2334471_2335884_-\|pyruvate-kinase	gnl\|CDD\|181699	PRK09206, PRK09206, pyruvate kinase PykF.	0

>CP028483.1|AWR73947.1|2344577_2344883_-|monooxygenase
MATLLQLHFSFNGPFGDTMAEQLKPLAESINQEPGFLWKVWTESEKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNVPLSQINQAKLA
>CP028483.1|AWR73946.1|2342847_2344452_-|FAD-NAD(P)-binding-protein
MKTIAIVGAGPTGIYTLFSLLQQQTPLSISIFDQADEAGIGMPYSDEENSKLMLANIASIEIPPIYCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNLNLPSETFDLAVIATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVTFHRDNANEKLNITLMSRTGILPEADFYCPIPYEPLHIITDQALNAEIQKGEVGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEENLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLALREAGIIHILALGEDYEMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPNVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGITACAEIGEAMARAVVKPASRARRRLSFD
>CP028483.1|AWR73945.1|2342023_2342836_+|hypothetical-protein
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGERLFCSQFVRSDDHARLGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGARARVAVTGNSSRISSAGDSGRIANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGCAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC
>CP028483.1|AWR73944.1|2341234_2342020_+|thiosulfate-reductase-cytochrome-B-subunit
MNPSQHAEQFQSQLANYVPQFTPQFWPVWLIIAGLLLVGMWLVLGLHALLRARGVKKSATDHSERIYLYSKAVRLWHWSNALLFVLLLASGLINHFALVGATAVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLDRAAKQTRFYLFGIMQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH
>CP028483.1|AWR76553.1|2340569_2341238_+|4Fe-4S-dicluster-domain-containing-protein
MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDESRCNGCNICARACRKTNHVPAQGSRLSIAHIPVIDNDNGTQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVRVEKSQCIGCSYCIGVCPYQVRYLNPVTKVADKCDFCAETRLAKGFPPICVSACPEHALIFGHEDSPEIQAWLQENKYYQYQLPGAGKPHLYRRFGQHLIKKENV
>CP028483.1|AWR73943.1|2339858_2340506_+|hypothetical-protein
MGEMNHQDELPLAKVSEIDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLENIKQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEAAIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>CP028483.1|AWR73942.1|2337752_2339855_+|aldehyde-ferredoxin-oxidoreductase
MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCVAAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTVSPLKSRNYRGDLALEAKFFKAITGEDMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPA
>CP028483.1|AWR73941.1|2337105_2337732_+|4Fe-4S-dicluster-domain-containing-protein
MNPVDRPLLNIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKESQCMNVCPIGAITWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>CP028483.1|AWR73940.1|2336440_2336650_+|fumarate-hydratase-FumD
MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>CP028483.1|AWR73939.1|2334471_2335884_-|pyruvate-kinase
MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGNSEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVVMVSGALVPSGTTNTASVHVL
>CP028483.1|AWR73948.1|2345456_2346713_+|hypothetical-protein
MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENTVVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRHPEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGELLVYPGGEACNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGAIYRLGTDGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRAPVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDSVTFGIGNINLNGGKLWLITDAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITDASRQTLCNALKLQPDEDGIGATLQPA
>CP028483.1|AWR73949.1|2346753_2348127_-|multidrug-resistance-protein-MdtK
MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRAAR
>CP028483.1|AWR73950.1|2348341_2348983_+|riboflavin-synthase
MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAHNGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGHIMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVHLIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA
>CP028483.1|AWR73951.1|2349022_2350171_-|cyclopropane-fatty-acyl-phospholipid-synthase
MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMICEKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTILLQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLNVDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR
>CP028483.1|AWR73952.1|2350461_2351673_-|Bcr/CflA-family-multidrug-efflux-MFS-transporter
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLFIGLTIFALGSLGMLWVENAATLLILRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQAIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHSESH
>CP028483.1|AWR73953.1|2351785_2352718_+|LysR-family-transcriptional-regulator
MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWLAVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIVRPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAFRDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKRLVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALKLENPFPDSACCLTWQQNDMSPALTWLLEYLGDSETLNKEWLREPEETPATGD
>CP028483.1|AWR73954.1|2352714_2353740_-|PurR-family-transcriptional-regulator
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQSHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADGPFRDYRR
>CP028483.1|AWR73955.1|2353727_2353952_-|hypothetical-protein
MISVFTTSPFRQDRPKFHAYTICVLAIDPFLTLRVVFPAYRNIFVVRKVCKGKRLPCEFAGAEVRVWSEMEWQQ
>CP028483.1|AWR73956.1|2354038_2354128_+|YnhF-family-membrane-protein
MSTDLKFSLVTTIIVLGLIVAVGLTAALH
>CP028483.1|AWR73957.1|2354293_2355463_+|MFS-transporter
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRMSFLATAGLGVISMVSLFLSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHVTPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNEFGAAISMVVWGAATFAIVPPLQMRVMRVASEAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPEAVCVANS

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Crispr_ID: CP028483_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028483_3

3223300-3223382

Orphan

I-F

Consensus_repeat	Method
ATCTGCCTGTACGGCAGTGAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP028483_3

>merge|CP028483|3|3223300-3223382|CRISPRCasFinder
ATCTGCCTGTACGGCAGTGAACTTGTCATTATTGGCAGACAGGATCCGCGGCAATTTCTAAGCTGCCTGTACGGCAGTGAACT

>CP028483|3|3|3223300-3223382|CRISPRCasFinder
ATCTGCCTGTACGGCAGTGAACT	TGTCATTATTGGCAGACAGGATCCGCGGCAATTTCTA
AGCTGCCTGTACGGCAGTGAACT

Protein	Signature genes	Signature genes Name	Protein_function
CP028483.1\|AWR74812.1\|3218171_3219938_+\|thiol-reductant-ABC-exporter-subunit-CydD	unknown	unknown	gnl\|CDD\|236870
CP028483.1\|AWR74822.1\|3231002_3232661_-\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
CP028483.1\|AWR74810.1\|3211805_3215912_-\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
CP028483.1\|AWR74819.1\|3226840_3228787_-\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl\|CDD\|182528
CP028483.1\|AWR74811.1\|3217083_3218049_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
CP028483.1\|AWR74816.1\|3223593_3225870_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828
CP028483.1\|AWR74818.1\|3226543_3226768_+\|cold-shock-protein-CspD	unknown	unknown	gnl\|CDD\|77494
CP028483.1\|AWR74815.1\|3222690_3222909_+\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
CP028483.1\|AWR74813.1\|3219938_3221660_+\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865
CP028483.1\|AWR74806.1\|3207852_3207993_+\|Hok/Gef-family-protein	unknown	unknown	gnl\|CDD\|366840
CP028483.1\|AWR74820.1\|3228783_3229899_-\|MacA-family-efflux-pump-subunit	unknown	unknown	gnl\|CDD\|183211
CP028483.1\|AWR76601.1\|3233863_3234046_-\|hypothetical-protein	unknown	unknown	unknown
CP028483.1\|AWR74807.1\|3208298_3209591_-\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
CP028483.1\|AWR74808.1\|3209681_3211025_-\|recombination-factor-protein-RarA	unknown	unknown	gnl\|CDD\|237355
CP028483.1\|AWR74809.1\|3211035_3211647_-\|outer-membrane-lipoprotein-carrier-protein-LolA	unknown	unknown	gnl\|CDD\|129638
CP028483.1\|AWR74823.1\|3232678_3232873_+\|hypothetical-protein	unknown	unknown	unknown
CP028483.1\|AWR74814.1\|3221701_3222406_+\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
CP028483.1\|AWR74817.1\|3225900_3226221_-\|ATP-dependent-Clp-protease-adaptor-ClpS	unknown	unknown	gnl\|CDD\|178809
CP028483.1\|AWR74821.1\|3230013_3231006_+\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|225537
CP028483.1\|AWR74824.1\|3233085_3233781_+\|aquaporin	unknown	unknown	gnl\|CDD\|235453

Protein	Function_ID	Function_description	E-value
CP028483.1\|AWR74812.1\|3218171_3219938_+\|thiol-reductant-ABC-exporter-subunit-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
CP028483.1\|AWR74822.1\|3231002_3232661_-\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
CP028483.1\|AWR74810.1\|3211805_3215912_-\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
CP028483.1\|AWR74819.1\|3226840_3228787_-\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
CP028483.1\|AWR74811.1\|3217083_3218049_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
CP028483.1\|AWR74816.1\|3223593_3225870_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
CP028483.1\|AWR74818.1\|3226543_3226768_+\|cold-shock-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
CP028483.1\|AWR74815.1\|3222690_3222909_+\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
CP028483.1\|AWR74813.1\|3219938_3221660_+\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
CP028483.1\|AWR74806.1\|3207852_3207993_+\|Hok/Gef-family-protein	gnl\|CDD\|366840	pfam01848, HOK_GEF, Hok/gef family.	0.000468008
CP028483.1\|AWR74820.1\|3228783_3229899_-\|MacA-family-efflux-pump-subunit	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
CP028483.1\|AWR74807.1\|3208298_3209591_-\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
CP028483.1\|AWR74808.1\|3209681_3211025_-\|recombination-factor-protein-RarA	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
CP028483.1\|AWR74809.1\|3211035_3211647_-\|outer-membrane-lipoprotein-carrier-protein-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
CP028483.1\|AWR74814.1\|3221701_3222406_+\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.92039e-139
CP028483.1\|AWR74817.1\|3225900_3226221_-\|ATP-dependent-Clp-protease-adaptor-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.48686e-49
CP028483.1\|AWR74821.1\|3230013_3231006_+\|DUF535-domain-containing-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	3.26125e-132
CP028483.1\|AWR74824.1\|3233085_3233781_+\|aquaporin	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	7.82992e-144

>CP028483.1|AWR74815.1|3222690_3222909_+|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>CP028483.1|AWR74814.1|3221701_3222406_+|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCDEFIRHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLSNNFWVPRCLFSPQE
>CP028483.1|AWR74813.1|3219938_3221660_+|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPKVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGIYLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMCEKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL
>CP028483.1|AWR74812.1|3218171_3219938_+|thiol-reductant-ABC-exporter-subunit-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLFLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQTALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGRYAELSVAGGPFATLLAHRQEEI
>CP028483.1|AWR74811.1|3217083_3218049_+|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNTDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>CP028483.1|AWR74810.1|3211805_3215912_-|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQSTVAWQPVPGPQTGEPVIAPAPEGYPQQPQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYATAAEQPAQQPYYAPAPEQAVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPTRPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNTEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQQQYQQPQQPVAQQPQYQQPQQPVTQQPQYQQPQQPVVPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>CP028483.1|AWR74809.1|3211035_3211647_-|outer-membrane-lipoprotein-carrier-protein-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>CP028483.1|AWR74808.1|3209681_3211025_-|recombination-factor-protein-RarA
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAVGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGCRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVYLLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>CP028483.1|AWR74807.1|3208298_3209591_-|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG
>CP028483.1|AWR74806.1|3207852_3207993_+|Hok/Gef-family-protein
MSQKSLTAITFCVTAILIIWMLHGSLCEIRMSFWGAEFAAFLQCKQ
>CP028483.1|AWR74816.1|3223593_3225870_-|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>CP028483.1|AWR74817.1|3225900_3226221_-|ATP-dependent-Clp-protease-adaptor-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>CP028483.1|AWR74818.1|3226543_3226768_+|cold-shock-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>CP028483.1|AWR74819.1|3226840_3228787_-|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLEWKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNATGGTEPVVNTASGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>CP028483.1|AWR74820.1|3228783_3229899_-|MacA-family-efflux-pump-subunit
MKKRKTVKKRYVIAMVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDNAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKINDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>CP028483.1|AWR74821.1|3230013_3231006_+|DUF535-domain-containing-protein
MVKSTSCITIDFMNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAELTFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFCS
>CP028483.1|AWR74822.1|3231002_3232661_-|ATP-dependent-endonuclease
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENIPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>CP028483.1|AWR74823.1|3232678_3232873_+|hypothetical-protein
MTYSLRWQYNGKGLLIRDGITFKHGKCLKNERIIALYSLLLISLQKQQNQIISMINYFLLRLKD
>CP028483.1|AWR74824.1|3233085_3233781_+|aquaporin
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRN
>CP028483.1|AWR76601.1|3233863_3234046_-|hypothetical-protein
MTNRTGVGGVKIADPVAVRDKSRAPRSGDFVRQSPGVQGAAAIGRPLHAPCASGNMWLSS

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Crispr_ID: CP028483_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP028483_4

4111572-4111704

Orphan

Consensus_repeat	Method
ATCACCAATATTGAAAA	PILER-CR

2 spacers

The CRISPR arrays of CP028483_4

>merge|CP028483|4|4111572-4111704|PILER-CR
ATCACCAATATTGAAAATGTCACACGCAGATAAATCCAACTTTCAATATTGTTAAGCTCCTCACCAATATTGAAAACATGGCGTAGCAAAAAGAAATTTTCAATATTGTTTTATGGATCACCAATATTGAAAG

>CP028483|4|1|4111572-4111704|PILER-CR
ATCACCAATATTGAAAA	TGTCACACGCAGATAAATCCAACTTTCAATATTGTTAAGCTC
CTCACCAATATTGAAAA	CATGGCGTAGCAAAAAGAAATTTTCAATATTGTTTTATGG
ATCACCAATATTGAAAG

Protein	Signature genes	Signature genes Name	Protein_function
CP028483.1\|AWR75631.1\|4108133_4108421_-\|ferredoxin-like-protein-FixX	unknown	unknown	gnl\|CDD\|185346
CP028483.1\|AWR75641.1\|4119221_4119617_-\|transcriptional-activatory-protein-CaiF	unknown	unknown	gnl\|CDD\|183154
CP028483.1\|AWR75629.1\|4106105_4106636_-\|glutathione-regulated-potassium-efflux-system-ancillary-protein-KefF	unknown	unknown	gnl\|CDD\|234852
CP028483.1\|AWR75625.1\|4102973_4103258_-\|plasmid-maintenance-protein-CcdB	unknown	unknown	gnl\|CDD\|376629
CP028483.1\|AWR75640.1\|4118512_4119103_+\|carnitine-operon-protein-CaiE	unknown	unknown	gnl\|CDD\|184189
CP028483.1\|AWR75643.1\|4119877_4123099_-\|carbamoyl-phosphate-synthase-large-chain	unknown	unknown	gnl\|CDD\|235393
CP028483.1\|AWR75644.1\|4123116_4124265_-\|carbamoyl-phosphate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|237139
CP028483.1\|AWR75626.1\|4103260_4103494_-\|antitoxin	unknown	unknown	gnl\|CDD\|227619
CP028483.1\|AWR75633.1\|4109754_4110696_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	unknown	unknown	gnl\|CDD\|235120
CP028483.1\|AWR75634.1\|4110710_4111481_-\|protein-FixA	unknown	unknown	gnl\|CDD\|179569
CP028483.1\|AWR75639.1\|4117721_4118507_+\|carnitinyl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|179599
CP028483.1\|AWR75628.1\|4104250_4106113_-\|glutathione-regulated-potassium-efflux-system-protein-KefC	unknown	unknown	gnl\|CDD\|235131
CP028483.1\|AWR75627.1\|4103579_4104059_-\|type-3-dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|182714
CP028483.1\|AWR75632.1\|4108417_4109704_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|182273
CP028483.1\|AWR75637.1\|4114769_4115987_+\|L-carnitine-CoA-transferase	unknown	unknown	gnl\|CDD\|179589
CP028483.1\|AWR75630.1\|4106743_4108075_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340874
CP028483.1\|AWR75636.1\|4113498_4114641_+\|crotonobetainyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|179566
CP028483.1\|AWR75635.1\|4111953_4113468_+\|L-carnitine/gamma-butyrobetaine-antiporter	unknown	unknown	gnl\|CDD\|179568
CP028483.1\|AWR75638.1\|4116059_4117613_+\|crotonobetaine/carnitine-CoA-ligase	unknown	unknown	gnl\|CDD\|181195
CP028483.1\|AWR75642.1\|4119651_4119870_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP028483.1\|AWR75631.1\|4108133_4108421_-\|ferredoxin-like-protein-FixX	gnl\|CDD\|185346	PRK15449, PRK15449, ferredoxin-like protein FixX; Provisional.	1.0161e-68
CP028483.1\|AWR75641.1\|4119221_4119617_-\|transcriptional-activatory-protein-CaiF	gnl\|CDD\|183154	PRK11476, PRK11476, carnitine metabolism transcriptional regulator CaiF.	2.21297e-74
CP028483.1\|AWR75629.1\|4106105_4106636_-\|glutathione-regulated-potassium-efflux-system-ancillary-protein-KefF	gnl\|CDD\|234852	PRK00871, PRK00871, glutathione-regulated potassium-efflux system oxidoreductase KefF.	2.99389e-133
CP028483.1\|AWR75625.1\|4102973_4103258_-\|plasmid-maintenance-protein-CcdB	gnl\|CDD\|376629	pfam01845, CcdB, CcdB protein.	1.5415e-33
CP028483.1\|AWR75640.1\|4118512_4119103_+\|carnitine-operon-protein-CaiE	gnl\|CDD\|184189	PRK13627, PRK13627, carnitine operon protein CaiE; Provisional.	4.67383e-142
CP028483.1\|AWR75643.1\|4119877_4123099_-\|carbamoyl-phosphate-synthase-large-chain	gnl\|CDD\|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
CP028483.1\|AWR75644.1\|4123116_4124265_-\|carbamoyl-phosphate-synthase-small-subunit	gnl\|CDD\|237139	PRK12564, PRK12564, carbamoyl-phosphate synthase small subunit.	0
CP028483.1\|AWR75626.1\|4103260_4103494_-\|antitoxin	gnl\|CDD\|227619	COG5302, COG5302, Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid [General function prediction only].	2.77856e-23
CP028483.1\|AWR75633.1\|4109754_4110696_-\|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein	gnl\|CDD\|235120	PRK03363, fixB, electron transfer flavoprotein subunit alpha/FixB family protein.	0
CP028483.1\|AWR75634.1\|4110710_4111481_-\|protein-FixA	gnl\|CDD\|179569	PRK03359, PRK03359, putative electron transfer flavoprotein FixA; Reviewed.	2.42827e-170
CP028483.1\|AWR75639.1\|4117721_4118507_+\|carnitinyl-CoA-dehydratase	gnl\|CDD\|179599	PRK03580, PRK03580, crotonobetainyl-CoA hydratase.	6.92249e-179
CP028483.1\|AWR75628.1\|4104250_4106113_-\|glutathione-regulated-potassium-efflux-system-protein-KefC	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	0
CP028483.1\|AWR75627.1\|4103579_4104059_-\|type-3-dihydrofolate-reductase	gnl\|CDD\|182714	PRK10769, folA, type 3 dihydrofolate reductase.	1.07206e-127
CP028483.1\|AWR75632.1\|4108417_4109704_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|182273	PRK10157, PRK10157, putative oxidoreductase FixC; Provisional.	0
CP028483.1\|AWR75637.1\|4114769_4115987_+\|L-carnitine-CoA-transferase	gnl\|CDD\|179589	PRK03525, PRK03525, L-carnitine CoA-transferase.	0
CP028483.1\|AWR75630.1\|4106743_4108075_-\|MFS-transporter	gnl\|CDD\|340874	cd17316, MFS_SV2_like, Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily. This family is composed of metazoan synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters including those that transport inorganic phosphate (Pht), aromatic compounds (PcaK and related proteins), proline/betaine (ProP), alpha-ketoglutarate (KgtP), citrate (CitA), shikimate (ShiA), and cis,cis-muconate (MucK), among others. SV2 is a transporter-like protein that serves as the receptor for botulinum neurotoxin A (BoNT/A), one of seven neurotoxins produced by the bacterium Clostridium botulinum. BoNT/A blocks neurotransmitter release by cleaving synaptosome-associated protein of 25 kD (SNAP-25) within presynaptic nerve terminals. Also included in this family is synaptic vesicle 2 (SV2)-related protein (SVOP) and similar proteins. SVOP is a transporter-like nucleotide binding protein that localizes to neurotransmitter-containing vesicles. The SV2-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.5672e-59
CP028483.1\|AWR75636.1\|4113498_4114641_+\|crotonobetainyl-CoA-dehydrogenase	gnl\|CDD\|179566	PRK03354, PRK03354, crotonobetainyl-CoA dehydrogenase; Validated.	0
CP028483.1\|AWR75635.1\|4111953_4113468_+\|L-carnitine/gamma-butyrobetaine-antiporter	gnl\|CDD\|179568	PRK03356, PRK03356, L-carnitine/gamma-butyrobetaine antiport BCCT transporter.	0
CP028483.1\|AWR75638.1\|4116059_4117613_+\|crotonobetaine/carnitine-CoA-ligase	gnl\|CDD\|181195	PRK08008, caiC, putative crotonobetaine/carnitine-CoA ligase; Validated.	0

>CP028483.1|AWR75634.1|4110710_4111481_-|protein-FixA
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTASVLAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVERELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI
>CP028483.1|AWR75633.1|4109754_4110696_-|electron-transfer-flavoprotein-subunit-alpha/FixB-family-protein
MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQAIQLGANHVWKLSGKPDERMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLNAAVSNDASAVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
>CP028483.1|AWR75632.1|4108417_4109704_-|FAD-dependent-oxidoreductase
MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRSYSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILADGVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTDGLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYSAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSAMKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFNGYPELAVGVARDLFTIDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL
>CP028483.1|AWR75631.1|4108133_4108421_-|ferredoxin-like-protein-FixX
MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACPAGLYKKRDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG
>CP028483.1|AWR75630.1|4106743_4108075_-|MFS-transporter
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADLVGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFEEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWTLPIFINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG
>CP028483.1|AWR75629.1|4106105_4106636_-|glutathione-regulated-potassium-efflux-system-ancillary-protein-KefF
MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQARHYKQRLLEWQEAHHG
>CP028483.1|AWR75628.1|4104250_4106113_-|glutathione-regulated-potassium-efflux-system-protein-KefC
MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRRAFAVLLFQDIAAIPLVAMIPLLAASSASTTMGAFVLSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
>CP028483.1|AWR75627.1|4103579_4104059_-|type-3-dihydrofolate-reductase
MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
>CP028483.1|AWR75626.1|4103260_4103494_-|antitoxin
MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKHAATRWREENAEAIAALNQLADETGCFSDEYRSF
>CP028483.1|AWR75625.1|4102973_4103258_-|plasmid-maintenance-protein-CcdB
MQFTVYRSRGRNAAFPFVIDVTSDIIGEINRRIVIPLTPIERFSRIRPPERLNPILLLIDGKEYVLMTHETATVPVNALGTKFCDASAHRTLIK
>CP028483.1|AWR75635.1|4111953_4113468_+|L-carnitine/gamma-butyrobetaine-antiporter
MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYFFFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSVLVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKY
>CP028483.1|AWR75636.1|4113498_4114641_+|crotonobetainyl-CoA-dehydrogenase
MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSAYTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
>CP028483.1|AWR75637.1|4114769_4115987_+|L-carnitine-CoA-transferase
MDHLTMPKFGPLSGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMTKGKDPYYAGCGLYKCADGYIVMELVGITQIAECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED
>CP028483.1|AWR75638.1|4116059_4117613_+|crotonobetaine/carnitine-CoA-ligase
MDIIGGQHLRQMWDDLADVYGHKTALICESSSGVVNRYSYLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESTWILQNSQACLLVNSAQFYPMYQQIQQEDASQLRHICLTDMALPADDGVSSFTQLKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDIYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSVRAFWGQVQKYRATVTECIPMMIRTLMVQPPSVNDRQHCLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
>CP028483.1|AWR75639.1|4117721_4118507_+|carnitinyl-CoA-dehydratase
MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGVVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMPVEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR
>CP028483.1|AWR75640.1|4118512_4119103_+|carnitine-operon-protein-CaiE
MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVLAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFRGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQDLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
>CP028483.1|AWR75641.1|4119221_4119617_-|transcriptional-activatory-protein-CaiF
MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNTLTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVRKTPRIPAVPLTELNREQKWQMMLSKSMRR
>CP028483.1|AWR75642.1|4119651_4119870_+|hypothetical-protein
MTRFAAIKQGHIKIVDISIVCNFTVDKCELNPAYVIKNIDSPKDLLNGQKKRSSSENRISYLIKLADEKYPP
>CP028483.1|AWR75643.1|4119877_4123099_-|carbamoyl-phosphate-synthase-large-chain
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHSMEEALAVAAEVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVERLKLKQPANATVTTIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK
>CP028483.1|AWR75644.1|4123116_4124265_-|carbamoyl-phosphate-synthase-small-subunit
MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYLKRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAKEVTTAEPYSWTQGSWTLTGGLPEAKKEDELPYHVVAYDFGAKRNILRMLVDRGCRLTIVPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIALIEQYRKTAK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP028483_4	4.1\|4111589\|42\|CP028483\|PILER-CR	4111589-4111630	42	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141085-141126	1	0.976
CP028483_1	1.1\|2345062\|38\|CP028483\|CRISPRCasFinder	2345062-2345099	38	NZ_CP043437	Enterobacter sp. LU1 plasmid unnamed	113727-113764	2	0.947
CP028483_2	2.1\|3023340\|40\|CP028483\|CRISPRCasFinder	3023340-3023379	40	NZ_CP041417	Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence	47951-47990	2	0.95
CP028483_4	4.2\|4111648\|40\|CP028483\|PILER-CR	4111648-4111687	40	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	141028-141067	2	0.95

1. spacer 4.1|4111589|42|CP028483|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 1, identity: 0.976

tgtcacacgcagataaatccaactttcaatattgttaagctc	CRISPR spacer
tgtcacacgcagataaatccaactttcaatattgttaagttc	Protospacer
***************************************.**

2. spacer 1.1|2345062|38|CP028483|CRISPRCasFinder matches to NZ_CP043437 (Enterobacter sp. LU1 plasmid unnamed) position: , mismatch: 2, identity: 0.947

cggacgcaggatggtgcgttcaattggactcgaaccaa	CRISPR spacer
cagacgcagaatggtgcgttcaattggactcgaaccaa	Protospacer
*.*******.****************************

3. spacer 2.1|3023340|40|CP028483|CRISPRCasFinder matches to NZ_CP041417 (Escherichia coli strain STEC711 plasmid pSTEC711_1, complete sequence) position: , mismatch: 2, identity: 0.95

gcgctgcgggtcatttttgaaattacctccgctgtgctgt	CRISPR spacer
gcgctgcgggtcattcttgaaattacccccgctgtgctgt	Protospacer
***************.***********.************

4. spacer 4.2|4111648|40|CP028483|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 2, identity: 0.95

catggcgtagcaaaaagaaattttcaatattgttttatgg	CRISPR spacer
catggcgtagaaaaaagaaattttcaatattgctttatgg	Protospacer
********** *********************.*******

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1773962 : 1783407

Enterobacteria_phage(85.71%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWR73414.1\|1773962_1774889_+	ABC transporter ATP-binding protein	F2Y1V5	Organic_Lake_phycodnavirus	2.6e-08	26.8
AWR73415.1\|1774893_1775625_+	ABC transporter permease	NA	NA	NA	NA
AWR73416.1\|1775605_1775713_-	hypothetical protein	NA	NA	NA	NA
AWR73417.1\|1775772_1776504_-	transcriptional regulator	Q9EYF2	Enterobacteria_phage	6.3e-111	98.5
AWR73418.1\|1776725_1778411_+	sensor histidine kinase	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
AWR73419.1\|1778407_1779127_+	DNA-binding response regulator	NA	NA	NA	NA
AWR73420.1\|1779173_1779644_+	DUF1456 domain-containing protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
AWR73421.1\|1779684_1780146_-	hypothetical protein	Q9EYF5	Enterobacteria_phage	3.2e-76	99.3
AWR73422.1\|1780270_1782274_-	hypothetical protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.7
AWR73423.1\|1782270_1783407_-	VWA domain-containing protein	Q9EYF7	Enterobacteria_phage	6.1e-161	96.7

DBSCAN-SWA_2

1877583 : 1883886

Enterobacteria_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWR73493.1\|1877583_1878978_+	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	6.3e-19	33.0
AWR73494.1\|1879152_1880046_+	GalU regulator GalF	A0A127AW70	Bacillus_phage	3.0e-46	42.0
AWR76522.1\|1880418_1881504_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	8.8e-101	53.9
AWR73495.1\|1881503_1882403_+	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	1.7e-28	34.8
AWR73496.1\|1882460_1883339_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	6.6e-107	64.5
AWR73497.1\|1883343_1883886_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	6.0e-50	61.8

DBSCAN-SWA_3

1906982 : 1940011

Stx2-converting_phage(21.43%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWR73521.1\|1906982_1907492_+\|transposase	IS200/IS605-like element IS200C family transposase	I4AZI8	Saccharomonospora_phage	1.8e-11	31.5
AWR73522.1\|1907602_1909030_-	exodeoxyribonuclease I	NA	NA	NA	NA
AWR73523.1\|1909238_1910405_+	serine-type D-Ala-D-Ala carboxypeptidase DacD	B6DZZ7	Stx2-converting_phage	5.9e-228	99.5
AWR73524.1\|1910523_1910997_+	DNA gyrase inhibitor SbmC	NA	NA	NA	NA
AWR73525.1\|1911194_1912253_+	FUSC family protein	NA	NA	NA	NA
AWR73526.1\|1912424_1912754_+	DUF496 domain-containing protein	NA	NA	NA	NA
AWR76525.1\|1912854_1913037_-	ethanolamine utilization protein	NA	NA	NA	NA
AWR76527.1\|1913525_1913639_-	DUF957 domain-containing protein	NA	NA	NA	NA
AWR76528.1\|1913651_1913843_-	hypothetical protein	NA	NA	NA	NA
AWR73527.1\|1913842_1914217_-	toxin	NA	NA	NA	NA
AWR73528.1\|1914305_1914674_-	type IV toxin-antitoxin system YeeU family antitoxin	NA	NA	NA	NA
AWR73529.1\|1914689_1915334_-	antitoxin of toxin-antitoxin stability system	A0A2I6PI07	Pseudomonas_phage	1.8e-24	32.9
AWR73530.1\|1915352_1915574_-	DUF987 domain-containing protein	A0A142F0X9	Klebsiella_phage	1.9e-10	45.8
AWR76526.1\|1915636_1916083_-	hypothetical protein	NA	NA	NA	NA
AWR73531.1\|1916128_1916602_-	antirestriction protein	A0A2D0W9W4	Bordetella_phage	4.3e-12	33.1
AWR73532.1\|1916695_1916941_-	antirestriction protein	NA	NA	NA	NA
AWR73533.1\|1916940_1917759_-	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	8.8e-45	38.6
AWR73534.1\|1917979_1918390_-	hypothetical protein	NA	NA	NA	NA
AWR73535.1\|1918838_1919585_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
AWR73536.1\|1919599_1921141_-\|transposase	IS21 family transposase ISEc12	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
AWR73537.1\|1921255_1921669_-	hypothetical protein	NA	NA	NA	NA
AWR73538.1\|1921804_1922875_-	patatin-like phospholipase family protein	NA	NA	NA	NA
AWR73539.1\|1922871_1923777_-	chemotaxis protein	NA	NA	NA	NA
AWR76529.1\|1923773_1924616_-	vimentin yjdA	NA	NA	NA	NA
AWR73540.1\|1924659_1926273_-\|transposase	IS66 family transposase ISEc23	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
AWR73541.1\|1926303_1926654_-	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
AWR73542.1\|1926650_1927076_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
AWR73543.1\|1927090_1928698_-	dGTPase	NA	NA	NA	NA
AWR73544.1\|1928915_1929350_-	hypothetical protein	NA	NA	NA	NA
AWR73545.1\|1929778_1931944_+	TonB-dependent siderophore receptor	NA	NA	NA	NA
AWR73546.1\|1931954_1932944_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
AWR73547.1\|1932962_1934021_+	iron ABC transporter permease	NA	NA	NA	NA
AWR73548.1\|1934017_1934785_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.5e-14	27.9
AWR73549.1\|1934838_1935096_+	hypothetical protein	NA	NA	NA	NA
AWR76530.1\|1935626_1936772_-	hypothetical protein	NA	NA	NA	NA
AWR73550.1\|1937181_1937442_-	hypothetical protein	NA	NA	NA	NA
AWR76531.1\|1937368_1937746_+	hypothetical protein	NA	NA	NA	NA
AWR73551.1\|1937971_1938151_-\|transposase	transposase	NA	NA	NA	NA
AWR73552.1\|1938296_1939319_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.0e-199	99.1
AWR73553.1\|1939315_1940011_+\|transposase	transposase	A0A2L1IVB6	Escherichia_phage	2.3e-118	88.4

DBSCAN-SWA_4

2066474 : 2148984

Pectobacterium_phage(23.81%)

tail,terminase,integrase,portal,capsid,tRNA,plate,head,holin

attL 2066289:2066348|attR 2108901:2109025

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2066289:2066348	attL	NA	NA	NA	NA
AWR73663.1\|2066474_2067491_-\|integrase	integrase	H9C152	Pectobacterium_phage	1.1e-126	63.6
AWR73664.1\|2067459_2067723_-	DUF4224 domain-containing protein	H9C153	Pectobacterium_phage	1.2e-06	38.0
AWR73665.1\|2067658_2067883_-	hypothetical protein	H9C154	Pectobacterium_phage	7.3e-10	56.3
AWR73666.1\|2067932_2068115_-	hypothetical protein	NA	NA	NA	NA
AWR73667.1\|2068114_2068684_-	hypothetical protein	H9C156	Pectobacterium_phage	6.1e-37	49.2
AWR73668.1\|2068680_2070897_-	hypothetical protein	H9C157	Pectobacterium_phage	4.7e-101	35.6
AWR73669.1\|2070927_2071248_-	hypothetical protein	NA	NA	NA	NA
AWR73670.1\|2072258_2072672_-	transcriptional regulator	A0A1B5FPF4	Escherichia_phage	8.7e-09	49.1
AWR73671.1\|2072770_2073001_+	transcriptional regulator	H6WRX5	Salmonella_phage	1.5e-21	63.2
AWR73672.1\|2073059_2073536_+	hypothetical protein	H9C162	Pectobacterium_phage	1.9e-23	48.6
AWR73673.1\|2073575_2073800_+	hypothetical protein	H9C163	Pectobacterium_phage	6.1e-17	54.1
AWR73674.1\|2073796_2074552_+	replication protein	H9C164	Pectobacterium_phage	2.4e-41	68.5
AWR73675.1\|2074541_2075957_+	helicase DnaB	H9C165	Pectobacterium_phage	6.6e-173	66.7
AWR73676.1\|2075995_2076406_+	hypothetical protein	NA	NA	NA	NA
AWR73677.1\|2076407_2076644_+	hypothetical protein	NA	NA	NA	NA
AWR73678.1\|2076640_2076952_+	DNA-binding protein	A0A222YXX1	Escherichia_phage	1.2e-34	65.7
AWR73679.1\|2076948_2077173_+	hypothetical protein	NA	NA	NA	NA
AWR73680.1\|2077360_2077582_+	hypothetical protein	NA	NA	NA	NA
AWR76540.1\|2077854_2078643_+	hypothetical protein	A0A0P0ZC44	Stx2-converting_phage	1.1e-39	69.8
AWR73681.1\|2078817_2079741_-	hypothetical protein	NA	NA	NA	NA
AWR73682.1\|2080929_2081628_+	lysogenic protein	Q858R8	Enterobacteria_phage	1.5e-117	91.4
AWR73683.1\|2082090_2082696_-	hypothetical protein	NA	NA	NA	NA
AWR73684.1\|2082705_2083194_-	ImmA/IrrE family metallo-endopeptidase	A0A142KB62	Gordonia_phage	6.4e-27	42.7
AWR73685.1\|2083592_2083826_-	hypothetical protein	NA	NA	NA	NA
AWR73686.1\|2084069_2084711_+	hypothetical protein	NA	NA	NA	NA
AWR73687.1\|2084862_2085042_+	hypothetical protein	NA	NA	NA	NA
AWR73688.1\|2085119_2085716_+	DUF1367 domain-containing protein	H9C173	Pectobacterium_phage	1.5e-70	64.1
AWR73689.1\|2085712_2086006_+	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	3.3e-34	70.5
AWR73690.1\|2086005_2086677_+	antitermination protein	Q7Y3X2	Yersinia_phage	1.9e-16	33.5
AWR73691.1\|2086789_2087173_+	hypothetical protein	NA	NA	NA	NA
AWR73692.1\|2087172_2087445_+\|holin	phage holin family protein	A0A0A0YPY6	Escherichia_phage	9.8e-09	42.9
AWR73693.1\|2087444_2087924_+	TIGR02594 family protein	A0A222YWL8	Escherichia_phage	4.6e-62	68.8
AWR73694.1\|2087931_2088126_+	hypothetical protein	NA	NA	NA	NA
AWR76541.1\|2088185_2088431_-	hypothetical protein	NA	NA	NA	NA
AWR73695.1\|2088799_2089366_+	hypothetical protein	A0A1I9KFT4	Aeromonas_phage	2.9e-31	46.2
AWR73696.1\|2089352_2091215_+\|terminase	phage terminase large subunit family protein	A0A1I9KF19	Aeromonas_phage	1.1e-191	53.2
AWR73697.1\|2091214_2091448_+	hypothetical protein	NA	NA	NA	NA
AWR73698.1\|2091444_2093019_+\|portal	phage portal protein	E4WL21	Enterobacteria_phage	8.6e-190	64.0
AWR73699.1\|2093018_2094326_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	4.9e-106	53.7
AWR73700.1\|2094325_2094655_+\|head	head protein	A0A2R9YJN3	Escherichia_phage	2.0e-08	39.5
AWR73701.1\|2094713_2095748_+\|capsid	minor capsid protein E	A0A2I6TCE5	Escherichia_phage	6.6e-106	56.5
AWR73702.1\|2095782_2096202_+	DNA-packaging protein	NA	NA	NA	NA
AWR73703.1\|2096198_2096579_+	hypothetical protein	NA	NA	NA	NA
AWR73704.1\|2096610_2097291_+	hypothetical protein	NA	NA	NA	NA
AWR73705.1\|2097287_2097824_+	hypothetical protein	NA	NA	NA	NA
AWR73706.1\|2097804_2098707_+\|plate	phage baseplate assembly protein V	NA	NA	NA	NA
AWR73707.1\|2098709_2099051_+\|plate	baseplate assembly protein	D4HTV2	Vibrio_phage	1.1e-20	51.6
AWR73708.1\|2099047_2099968_+\|plate	baseplate assembly protein	D5LGZ3	Escherichia_phage	6.4e-68	47.8
AWR73709.1\|2099970_2100597_+\|tail	phage tail protein I	A0A193GYD1	Enterobacter_phage	2.0e-25	38.8
AWR73710.1\|2100589_2101774_+	hypothetical protein	J9QDX3	Clostridium_phage	2.5e-16	35.2
AWR73711.1\|2101773_2102163_+	hypothetical protein	A0A2H4EXG4	Aeromonas_phage	9.4e-05	30.8
AWR73712.1\|2102159_2103662_+\|tail	phage tail protein	R9TMQ0	Vibrio_phage	5.5e-69	33.5
AWR73713.1\|2103679_2104192_+\|tail	phage tail protein	NA	NA	NA	NA
AWR73714.1\|2104204_2104486_+\|tail	phage tail assembly protein	NA	NA	NA	NA
AWR73715.1\|2104594_2106235_+	hypothetical protein	A0A2I7R3J9	Vibrio_phage	1.2e-19	29.3
AWR76542.1\|2106270_2106660_+	hypothetical protein	E5FFG4	Burkholderia_phage	1.0e-14	37.9
AWR73716.1\|2106821_2107046_+\|tail	phage tail protein	NA	NA	NA	NA
AWR73717.1\|2108260_2108680_+	hypothetical protein	G8C7Q7	Escherichia_phage	1.8e-49	68.8
AWR73718.1\|2109151_2109817_+	YecA family protein	NA	NA	NA	NA
2108901:2109025	attR	NA	NA	NA	NA
AWR73719.1\|2109867_2111079_-	tyrosine transporter	NA	NA	NA	NA
AWR73720.1\|2111269_2111509_+	DUF2492 domain-containing protein	NA	NA	NA	NA
AWR73721.1\|2111546_2112044_-	non-heme ferritin	NA	NA	NA	NA
AWR73722.1\|2112215_2112539_-	hypothetical protein	NA	NA	NA	NA
AWR73723.1\|2112745_2112892_-	hypothetical protein	NA	NA	NA	NA
AWR73724.1\|2113003_2113255_+	DUF2766 domain-containing protein	NA	NA	NA	NA
AWR73725.1\|2113332_2113836_-	non-heme ferritin	NA	NA	NA	NA
AWR73726.1\|2114305_2114545_+	hypothetical protein	NA	NA	NA	NA
AWR73727.1\|2114630_2115620_+	arabinose ABC transporter substrate-binding protein	NA	NA	NA	NA
AWR73728.1\|2115689_2117204_+	arabinose import ATP-binding protein AraG	A0A285PWH2	Cedratvirus	1.3e-12	29.7
AWR73729.1\|2117218_2118205_+	L-arabinose ABC transporter permease AraH	NA	NA	NA	NA
AWR73730.1\|2118371_2119172_+	trehalose-phosphatase	NA	NA	NA	NA
AWR73731.1\|2119146_2120571_+	trehalose-6-phosphate synthase	NA	NA	NA	NA
AWR73732.1\|2120577_2121006_-	universal stress protein UspC	NA	NA	NA	NA
AWR73733.1\|2121785_2122136_+	flagellar transcriptional activator FlhD	NA	NA	NA	NA
AWR73734.1\|2122138_2122717_+	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
AWR73735.1\|2122843_2123731_+	flagellar motor stator protein MotA	NA	NA	NA	NA
AWR73736.1\|2123727_2124654_+	motility protein MotB	NA	NA	NA	NA
AWR73737.1\|2124658_2126623_+	chemotaxis protein CheA	NA	NA	NA	NA
AWR73738.1\|2126643_2127147_+	chemotaxis protein CheW	NA	NA	NA	NA
AWR73739.1\|2127291_2128953_+	methyl-accepting chemotaxis protein II	A0A2H4J162	uncultured_Caudovirales_phage	1.7e-10	40.3
AWR73740.1\|2129243_2130104_+	protein-glutamate O-methyltransferase CheR	NA	NA	NA	NA
AWR73741.1\|2130106_2131156_+	chemotaxis response regulator protein-glutamate methylesterase	Q56AR1	Bacillus_thuringiensis_phage	1.0e-05	32.8
AWR73742.1\|2131170_2131560_+	two-component system response regulator	A0A2K9L4R0	Tupanvirus	1.3e-06	32.0
AWR73743.1\|2131570_2132215_+	protein phosphatase CheZ	NA	NA	NA	NA
AWR73744.1\|2132403_2133552_+	flagellar type III secretion system protein FlhB	NA	NA	NA	NA
AWR73745.1\|2133544_2135623_+	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
AWR73746.1\|2135622_2136015_+	flagellar protein FlhE	NA	NA	NA	NA
AWR73747.1\|2136067_2137801_-\|tRNA	arginine--tRNA ligase	A0A2K9L6Z2	Tupanvirus	8.8e-87	33.7
AWR76543.1\|2138016_2138583_+	VOC family protein	NA	NA	NA	NA
AWR73748.1\|2138596_2139343_+	copper homeostasis protein CutC	NA	NA	NA	NA
AWR73749.1\|2139730_2140831_+	cytochrome C	NA	NA	NA	NA
AWR73750.1\|2140855_2143285_+	molybdopterin guanine dinucleotide-containing S/N-oxide reductase	NA	NA	NA	NA
AWR73751.1\|2143320_2144292_-\|tRNA	tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB	NA	NA	NA	NA
AWR73752.1\|2144288_2145032_-	carboxy-S-adenosyl-L-methionine synthase CmoA	F5B419	Synechococcus_phage	4.6e-24	30.0
AWR73753.1\|2145072_2145468_-	hypothetical protein	NA	NA	NA	NA
AWR73754.1\|2145520_2146339_-	DUF72 domain-containing protein	Q859D1	Escherichia_coli_phage	6.5e-72	99.2
AWR73755.1\|2146335_2146902_-	hydrolase	NA	NA	NA	NA
AWR73756.1\|2147211_2148984_+\|tRNA	aspartate--tRNA ligase	NA	NA	NA	NA

DBSCAN-SWA_5

2646640 : 2717475

Enterobacteria_phage(26.67%)

transposase,terminase,portal,capsid,protease,holin,head,lysis,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWR74219.1\|2646640_2647690_-\|protease	protease SohB	A0A2H4UUF9	Bodo_saltans_virus	1.3e-21	31.5
AWR74220.1\|2647909_2648668_+	NAD(P)-dependent oxidoreductase	A0A0N9R355	Chrysochromulina_ericina_virus	4.4e-06	23.4
AWR74221.1\|2648664_2649255_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
AWR74222.1\|2649311_2649620_-	hypothetical protein	NA	NA	NA	NA
AWR76567.1\|2649629_2650616_-	hypothetical protein	NA	NA	NA	NA
AWR74223.1\|2651910_2653806_-	DUF2207 domain-containing protein	NA	NA	NA	NA
AWR74224.1\|2653833_2654454_-	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
AWR74225.1\|2654450_2655332_-	phosphatase	NA	NA	NA	NA
AWR76568.1\|2655469_2655514_+	trp operon leader peptide	NA	NA	NA	NA
AWR74226.1\|2655605_2657168_+	anthranilate synthase component I	NA	NA	NA	NA
AWR74227.1\|2657167_2658763_+	bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD	A0A0N7IRD9	Acinetobacter_phage	3.8e-52	38.5
AWR74228.1\|2658766_2660125_+	bifunctional indole-3-glycerol-phosphate synthase TrpC/phosphoribosylanthranilate isomerase TrpF	A0A0P0IR83	Acinetobacter_phage	3.9e-37	41.2
AWR74229.1\|2660136_2661330_+	tryptophan synthase subunit beta	NA	NA	NA	NA
AWR74230.1\|2661329_2662136_+	tryptophan synthase subunit alpha	NA	NA	NA	NA
AWR74231.1\|2662511_2662787_+	hypothetical protein	S5MQL6	Escherichia_phage	1.1e-10	52.9
AWR74232.1\|2662783_2663341_+	Rha family transcriptional regulator	Q8H9L9	Vibrio_phage	4.2e-30	63.8
AWR74233.1\|2663752_2664022_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	9.3e-20	79.4
AWR76569.1\|2664120_2664747_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
AWR74234.1\|2664691_2664829_-\|capsid	nucleocapsid protein	NA	NA	NA	NA
AWR76570.1\|2664945_2665128_-	recombinase family protein	A0A0C4UR34	Shigella_phage	1.4e-24	95.0
AWR74235.1\|2665253_2666222_+\|tail	phage tail protein	A0A0F7LDR4	Escherichia_phage	6.5e-47	38.8
AWR74236.1\|2666237_2666765_+\|tail	tail fiber assembly protein	A0A0C4UR05	Shigella_phage	8.4e-73	77.7
AWR74237.1\|2666795_2667329_-\|tail	tail fiber assembly protein	A0A077SL44	Escherichia_phage	1.8e-67	70.1
AWR74238.1\|2667330_2670156_-\|tail	phage tail protein	Q858V4	Yersinia_virus	9.0e-04	63.6
AWR74239.1\|2670617_2671364_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
AWR74240.1\|2671378_2672920_-\|transposase	IS21 family transposase ISEc12	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
AWR74241.1\|2673560_2677034_-	host specificity protein J	A0A0P0ZBW1	Stx2-converting_phage	0.0e+00	89.7
AWR74242.1\|2677376_2678057_-\|tail	tail assembly protein	B6ETG3	Enterobacteria_phage	3.8e-110	97.8
AWR74243.1\|2677954_2678698_-\|tail	phage tail protein	Q6H9T4	Enterobacteria_phage	4.3e-147	97.6
AWR74244.1\|2678708_2679407_-\|tail	phage minor tail protein L	B6DZB1	Enterobacteria_phage	5.8e-130	97.4
AWR74245.1\|2679406_2679748_-\|tail	phage tail protein	A0A0P0ZBQ8	Stx2-converting_phage	9.0e-60	95.6
AWR74246.1\|2679740_2682983_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	0.0e+00	91.6
AWR74247.1\|2683030_2683312_-	DUF4035 domain-containing protein	H6WZM0	Escherichia_phage	2.3e-45	98.9
AWR74248.1\|2683335_2683710_-\|tail	phage tail protein	A0A0P0ZE84	Stx2-converting_phage	1.7e-64	99.2
AWR74249.1\|2683724_2684441_-\|tail	phage tail protein	A0A0P0ZDV1	Stx2-converting_phage	3.6e-127	99.6
AWR74250.1\|2684507_2684852_-	DUF3168 domain-containing protein	A0A0P0ZC17	Stx2-converting_phage	1.4e-57	100.0
AWR74251.1\|2684848_2685295_-	hypothetical protein	A0A0N7KZI9	Stx2-converting_phage	5.2e-76	100.0
AWR74252.1\|2685291_2685642_-\|head,tail	head-tail adaptor protein	A0A0P0ZB28	Stx2-converting_phage	1.6e-59	100.0
AWR74253.1\|2685651_2685978_-\|head,tail	phage gp6-like head-tail connector protein	A0A0P0ZBH1	Stx2-converting_phage	9.2e-54	100.0
AWR74254.1\|2685974_2688560_-\|portal	phage portal protein	A0A0P0ZDD0	Stx2-converting_phage	0.0e+00	100.0
AWR74255.1\|2688505_2688727_-	hypothetical protein	B6DZA0	Enterobacteria_phage	5.8e-36	100.0
AWR74256.1\|2688771_2690709_-\|capsid	phage major capsid protein	H6WZL0	Escherichia_phage	0.0e+00	100.0
AWR74257.1\|2690772_2692434_-\|terminase	terminase large subunit	B6DZ98	Enterobacteria_phage	0.0e+00	98.7
AWR74258.1\|2692430_2692994_-\|terminase	terminase small subunit	A0A0P0ZD56	Stx2-converting_phage	1.6e-82	92.0
AWR74259.1\|2693284_2693650_-	HNH endonuclease	B6ETE5	Enterobacteria_phage	2.5e-60	93.4
AWR74260.1\|2693691_2693892_+	DUF3950 domain-containing protein	H6WZK6	Escherichia_phage	4.3e-30	98.5
AWR76571.1\|2693929_2694094_-	hypothetical protein	Q9T1L1	Enterobacteria_phage	3.3e-12	77.8
AWR74261.1\|2694090_2694306_-	hypothetical protein	NA	NA	NA	NA
AWR74262.1\|2694302_2694797_-\|lysis	lysis protein	Q9ZXB6	Enterobacteria_phage	1.7e-72	87.7
AWR76572.1\|2694798_2694885_-	hypothetical protein	NA	NA	NA	NA
AWR74263.1\|2695149_2695362_-	hypothetical protein	A0A0M4S639	Salmonella_phage	2.7e-06	60.5
AWR74264.1\|2695439_2695973_-	lysozyme	Q6H9V6	Enterobacteria_phage	4.8e-100	95.5
AWR74265.1\|2696141_2696567_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
AWR74266.1\|2696563_2696914_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
AWR74267.1\|2696944_2698558_+\|transposase	IS66 family transposase ISEc23	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
AWR74268.1\|2698618_2698891_+	hypothetical protein	NA	NA	NA	NA
AWR74269.1\|2698856_2699201_-	DUF1327 domain-containing protein	K7PGU6	Enterobacteria_phage	2.8e-37	95.2
AWR74270.1\|2699205_2699421_-\|holin	holin	G9L6J5	Escherichia_phage	9.0e-34	100.0
AWR74271.1\|2699571_2701425_-	DUF1737 domain-containing protein	Q08JA2	Stx2-converting_phage	0.0e+00	90.3
AWR74272.1\|2701685_2702021_+	anti-adapter protein IraM	Q8HAJ1	Enterobacteria_phage	5.2e-44	74.8
AWR74273.1\|2702301_2702433_-	DUF3927 domain-containing protein	H6WZJ7	Escherichia_phage	1.1e-05	100.0
AWR76573.1\|2702468_2702795_-	hypothetical protein	NA	NA	NA	NA
AWR74274.1\|2703234_2704284_-	site-specific DNA-methyltransferase	A0A0N7KZF8	Stx2-converting_phage	4.4e-198	95.4
AWR74275.1\|2704435_2704633_-	TrmB family transcriptional regulator	Q9MC00	Enterobacteria_phage	6.1e-29	98.5
AWR74276.1\|2704859_2705681_-	antitermination protein	K7P7B9	Enterobacteria_phage	1.7e-80	60.1
AWR74277.1\|2705677_2706058_-	RusA family crossover junction endodeoxyribonuclease	V5URS4	Shigella_phage	2.9e-35	64.5
AWR74278.1\|2706058_2707114_-	DUF968 domain-containing protein	A0A291AWV9	Escherichia_phage	4.0e-90	48.4
AWR74279.1\|2707115_2707388_-	hypothetical protein	I6PCV7	Cronobacter_phage	5.5e-12	49.2
AWR76574.1\|2707334_2707514_+	hypothetical protein	NA	NA	NA	NA
AWR74280.1\|2707555_2707768_-	Hok/Gef family protein	A0A0U2QV81	Escherichia_phage	5.2e-26	90.0
AWR74281.1\|2707948_2708614_-	hypothetical protein	NA	NA	NA	NA
AWR74282.1\|2708788_2709214_-	DUF977 domain-containing protein	A0A0U2QQN3	Escherichia_phage	2.2e-63	94.0
AWR74283.1\|2709229_2710000_-	DUF1627 domain-containing protein	A0A0U2SAW4	Escherichia_phage	1.6e-80	64.5
AWR74284.1\|2710021_2710768_-	DNA replication protein DnaC	A0A088CBP4	Shigella_phage	4.0e-113	83.8
AWR76575.1\|2710774_2711737_-	DNA-binding protein	S5FM81	Shigella_phage	1.4e-70	56.4
AWR74285.1\|2711759_2712185_-	Rha family transcriptional regulator	NA	NA	NA	NA
AWR74286.1\|2712181_2712397_-	transcriptional regulator	NA	NA	NA	NA
AWR74287.1\|2712446_2713163_+	LexA family transcriptional repressor	H9C160	Pectobacterium_phage	1.7e-52	42.0
AWR76576.1\|2713435_2713591_+	DUF1391 domain-containing protein	M4QQ57	Salicola_phage	8.8e-07	51.1
AWR74288.1\|2713550_2713721_+	hypothetical protein	NA	NA	NA	NA
AWR74289.1\|2713750_2713969_+	hypothetical protein	NA	NA	NA	NA
AWR74290.1\|2714017_2714212_-	hypothetical protein	NA	NA	NA	NA
AWR74291.1\|2714534_2714723_+	cell division inhibition protein DicB	NA	NA	NA	NA
AWR74292.1\|2714719_2714911_+	DUF1482 domain-containing protein	NA	NA	NA	NA
AWR74293.1\|2715003_2717475_+	exonuclease	A0A192Y6E0	Salmonella_phage	5.7e-55	56.0

DBSCAN-SWA_6

2856855 : 2902564

Enterobacteria_phage(56.0%)

terminase,integrase,portal,capsid,tRNA,holin,head,tail

attL 2875639:2875653|attR 2904233:2904247

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWR74432.1\|2856855_2857134_-	hypothetical protein	A0A0E3JSQ1	Enterobacteria_phage	9.9e-25	55.4
AWR74433.1\|2857130_2859152_-\|tail	phage tail protein	A0A0E3M0V5	Enterobacteria_phage	7.2e-181	72.3
AWR74434.1\|2859210_2862693_-	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	90.3
AWR74435.1\|2862753_2863395_-\|tail	tail assembly protein	A5LH42	Enterobacteria_phage	2.9e-96	86.5
AWR74436.1\|2863292_2864036_-\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	5.0e-148	97.2
AWR74437.1\|2864040_2864739_-\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	5.1e-134	99.6
AWR74438.1\|2864738_2865068_-\|tail	phage tail protein	A0A0K2FIE9	Enterobacteria_phage	2.8e-58	99.1
AWR74439.1\|2865064_2867626_-\|tail	phage tail tape measure protein	A0A0K2FI43	Enterobacteria_phage	0.0e+00	98.4
AWR74440.1\|2867618_2868053_-\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	6.9e-65	100.0
AWR74441.1\|2868034_2868457_-\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	2.2e-68	94.3
AWR76583.1\|2868472_2869213_-\|tail	phage tail protein	A0A2I6TC77	Escherichia_phage	1.6e-130	98.0
AWR74442.1\|2869220_2869616_-\|tail	phage tail protein	A0A2R9YJI2	Escherichia_phage	2.9e-70	98.5
AWR74443.1\|2869612_2870191_-\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	5.9e-80	92.7
AWR74444.1\|2870202_2870556_-\|tail	phage tail protein	A0A2R9YJJ5	Escherichia_phage	2.2e-61	98.3
AWR74445.1\|2870567_2870966_-	DNA-packaging protein FI	A0A0K2FIR1	Enterobacteria_phage	1.0e-62	98.5
AWR74446.1\|2871007_2872033_-\|capsid	minor capsid protein E	C6ZCY2	Enterobacteria_phage	7.8e-192	99.4
AWR74447.1\|2872088_2872421_-\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	3.8e-55	99.1
AWR74448.1\|2872430_2873750_-	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.1e-230	97.7
AWR74449.1\|2873730_2875332_-\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.4e-309	98.9
AWR74450.1\|2875328_2875535_-\|head,tail	Lambda prophage-derived head-to-tail joining protein W	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
AWR74451.1\|2875531_2877457_-\|terminase	terminase	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	98.9
2875639:2875653	attL	NA	NA	NA	NA
AWR74452.1\|2877431_2877977_-\|terminase	terminase small subunit	A0A0K2FIG2	Enterobacteria_phage	6.8e-94	98.3
AWR74453.1\|2878116_2878311_-	DNA-packaging protein	NA	NA	NA	NA
AWR74454.1\|2878245_2878566_+	hypothetical protein	NA	NA	NA	NA
AWR74455.1\|2878453_2878807_+	hypothetical protein	NA	NA	NA	NA
AWR74456.1\|2878929_2879310_-	hypothetical protein	H6WZK5	Escherichia_phage	2.6e-39	72.2
AWR74457.1\|2879736_2880030_+	lipoprotein bor	K7PL54	Enterobacteria_phage	7.0e-45	92.8
AWR74458.1\|2880120_2880303_-	hypothetical protein	K7PHU6	Enterobacteria_phage	2.9e-17	98.3
AWR74459.1\|2880519_2880996_-	lysozyme	K7PKV2	Enterobacteria_phage	7.3e-84	94.9
AWR74460.1\|2880982_2881300_-\|holin	holin	A0A286N2Q5	Klebsiella_phage	3.3e-40	86.1
AWR74461.1\|2881609_2882299_-	antitermination protein	I6PDF8	Cronobacter_phage	4.9e-57	48.5
AWR74462.1\|2882295_2882436_-	YlcG family protein	K7PHH3	Enterobacteria_phage	8.5e-09	68.9
AWR74463.1\|2882432_2882795_-	RusA family crossover junction endodeoxyribonuclease	K7PM48	Enterobacteria_phage	1.6e-59	95.7
AWR74464.1\|2882791_2883082_-	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	2.3e-48	95.8
AWR74465.1\|2883074_2883245_-	hypothetical protein	K7P7K0	Enterobacteria_phage	2.4e-13	69.8
AWR74466.1\|2883244_2883700_-	hypothetical protein	I6PD71	Cronobacter_phage	1.6e-59	66.9
AWR74467.1\|2883696_2883798_-	hypothetical protein	NA	NA	NA	NA
AWR74468.1\|2884147_2885191_+	alpha/beta hydrolase	NA	NA	NA	NA
AWR74469.1\|2885227_2889493_-	inverse autotransporter beta-barrel domain-containing protein	NA	NA	NA	NA
AWR74470.1\|2889742_2890444_-	Replication protein P	M1FJ72	Enterobacteria_phage	1.5e-125	97.0
AWR74471.1\|2890440_2891460_-	Replication protein O	A0A0M5M7Y1	Salmonella_phage	8.8e-111	64.1
AWR74472.1\|2891456_2891996_-	regulator	K7PJT7	Enterobacteria_phage	2.6e-61	67.0
AWR74473.1\|2892065_2892296_-	transcriptional regulator	A0A2H4FNF3	Salmonella_phage	1.5e-21	68.0
AWR74474.1\|2892334_2893090_+	hypothetical protein	Q76H56	Enterobacteria_phage	4.0e-92	74.6
AWR74475.1\|2893685_2893892_+	cell division inhibitor protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
AWR74476.1\|2893967_2894264_+	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	8.9e-48	98.0
AWR74477.1\|2894269_2895055_+	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
AWR74478.1\|2895051_2895732_+	exonuclease	A0A0P0ZCD4	Stx2-converting_phage	1.6e-132	100.0
AWR74479.1\|2895728_2895911_+	DUF1317 domain-containing protein	A0A1U8QQC1	Enterobacteria_phage	1.8e-27	98.3
AWR74480.1\|2895883_2896075_+	DUF1382 domain-containing protein	A0A0P0ZC67	Stx2-converting_phage	1.8e-25	93.7
AWR74481.1\|2896085_2896367_+	cell division protein ZapA	A0A0P0ZE02	Stx2-converting_phage	3.0e-45	95.7
AWR74482.1\|2896465_2896687_+	conjugal transfer protein TraR	A0A1I9LJM6	Stx_converting_phage	2.3e-32	93.2
AWR74483.1\|2896686_2897013_+	ASCH domain-containing protein	A5VWB6	Enterobacteria_phage	9.8e-48	95.7
AWR74484.1\|2896996_2897236_+	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	4.7e-39	96.2
AWR74485.1\|2897375_2897612_+	excisionase	NA	NA	NA	NA
AWR74486.1\|2897601_2898744_+\|integrase	integrase	Q77Z02	Phage_21	3.6e-206	100.0
AWR74487.1\|2898857_2900108_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0
AWR74488.1\|2900279_2900933_+	23S rRNA pseudouridine synthase E	NA	NA	NA	NA
AWR74489.1\|2900942_2901404_+	NUDIX hydrolase	NA	NA	NA	NA
AWR74490.1\|2901457_2902564_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
2904233:2904247	attR	NA	NA	NA	NA

DBSCAN-SWA_7

3099672 : 3226221

146

Enterobacteria_phage(42.42%)

transposase,plate,terminase,integrase,portal,capsid,protease,holin,tRNA,head,tail

attL 3169600:3169619|attR 3208257:3208276

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWR74674.1\|3099672_3100458_-\|tRNA	tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM	NA	NA	NA	NA
AWR74675.1\|3100593_3101373_+	envelope biogenesis factor ElyC	NA	NA	NA	NA
AWR74676.1\|3101349_3102243_-	hypothetical protein	NA	NA	NA	NA
AWR74677.1\|3102396_3103143_-	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
AWR74678.1\|3103139_3103322_-	protein YcaR	NA	NA	NA	NA
AWR74679.1\|3103373_3104606_-	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
AWR74680.1\|3104642_3105629_-	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
AWR74681.1\|3105625_3107374_-	lipid A export ATP-binding/permease MsbA	W8CYL7	Bacillus_phage	3.3e-57	29.8
AWR74682.1\|3107410_3109675_-	ComEC family protein	NA	NA	NA	NA
AWR74683.1\|3109880_3110165_-	integration host factor subunit beta	A7KV42	Bacillus_phage	3.2e-10	40.2
AWR74684.1\|3110324_3111998_-	30S ribosomal protein S1	NA	NA	NA	NA
AWR74685.1\|3112108_3112792_-	cytidylate kinase	NA	NA	NA	NA
AWR74686.1\|3112964_3113747_-\|protease	metalloprotease	NA	NA	NA	NA
AWR74687.1\|3113890_3114280_-	DNA-binding protein	Q6QIE8	Burkholderia_phage	1.5e-31	54.2
AWR74688.1\|3114251_3114701_-	regulatory protein GemA	A4JWM5	Burkholderia_virus	6.1e-24	45.1
AWR74689.1\|3114702_3114909_-	hypothetical protein	NA	NA	NA	NA
AWR74690.1\|3114898_3115129_-	hypothetical protein	NA	NA	NA	NA
AWR74691.1\|3115125_3115809_-	DUF2786 domain-containing protein	A0A2P9JZH4	Alteromonadaceae_phage	1.1e-32	36.1
AWR74692.1\|3115805_3116021_-	hypothetical protein	NA	NA	NA	NA
AWR74693.1\|3116035_3116332_-	hypothetical protein	NA	NA	NA	NA
AWR74694.1\|3116341_3116614_-	hypothetical protein	NA	NA	NA	NA
AWR74695.1\|3116670_3116892_+	hypothetical protein	NA	NA	NA	NA
AWR74696.1\|3116902_3117433_-	host-nuclease inhibitor protein Gam	L7P7T1	Pseudomonas_phage	1.2e-58	66.7
AWR74697.1\|3117460_3117730_-	hypothetical protein	NA	NA	NA	NA
AWR74698.1\|3117732_3118899_-	hypothetical protein	A4JWN1	Burkholderia_virus	2.2e-121	59.4
AWR74699.1\|3118909_3120679_-\|integrase	integrase	A4JWN2	Burkholderia_virus	1.5e-227	69.4
AWR74700.1\|3120694_3121012_-	hypothetical protein	NA	NA	NA	NA
AWR74701.1\|3121011_3121932_-	DUF3102 domain-containing protein	A4JWN3	Burkholderia_virus	1.6e-74	56.2
AWR74702.1\|3121942_3122251_-	IclR family transcriptional regulator	Q5ZR02	Pseudomonas_phage	2.7e-23	55.9
AWR74703.1\|3122303_3122492_-	DNA-binding protein	Q5ZQZ9	Pseudomonas_phage	3.9e-17	71.0
AWR74704.1\|3122585_3122942_+	XRE family transcriptional regulator	NA	NA	NA	NA
AWR74705.1\|3123058_3123823_-	DNA adenine methylase	A2I2Y7	Vibrio_virus	5.2e-100	64.4
AWR74706.1\|3124013_3124229_-	hypothetical protein	NA	NA	NA	NA
AWR74707.1\|3124227_3124632_+	hypothetical protein	NA	NA	NA	NA
AWR74708.1\|3124607_3125336_-	hypothetical protein	NA	NA	NA	NA
AWR74709.1\|3125466_3125817_+	hypothetical protein	A4JWP3	Burkholderia_virus	1.5e-22	53.0
AWR74710.1\|3125819_3126560_+	lytic transglycosylase domain-containing protein	Q5ZQZ1	Pseudomonas_phage	2.5e-62	51.4
AWR74711.1\|3126543_3127194_+	hypothetical protein	J9SVN7	Pseudomonas_phage	2.8e-09	32.9
AWR74712.1\|3127190_3127517_+	hypothetical protein	Q6QIC4	Burkholderia_phage	1.1e-17	48.6
AWR74713.1\|3127516_3127828_+	hypothetical protein	A0A0S4L0A3	Pseudomonas_phage	9.4e-32	62.6
AWR74714.1\|3127827_3128373_+	DUF3486 domain-containing protein	A4JWJ3	Burkholderia_virus	9.3e-59	67.6
AWR74715.1\|3128752_3129178_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
AWR74716.1\|3129174_3129525_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
AWR74717.1\|3129555_3131169_+\|transposase	IS66 family transposase ISEc23	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
AWR74718.1\|3132504_3134001_+	DUF935 domain-containing protein	A4JWJ5	Burkholderia_virus	9.7e-167	59.0
AWR74719.1\|3133981_3134803_+\|head	phage head morphogenesis protein	A4JWJ6	Burkholderia_virus	1.8e-98	61.9
AWR74720.1\|3134805_3135264_+	phage virion morphogenesis protein	Q6QIB8	Burkholderia_phage	2.6e-30	44.8
AWR74721.1\|3135478_3136594_+	peptidase	A4JWJ9	Burkholderia_virus	9.4e-98	51.6
AWR74722.1\|3136608_3137562_+	hypothetical protein	A4JWK0	Burkholderia_virus	3.4e-64	43.8
AWR74723.1\|3137571_3137910_+	DUF2190 domain-containing protein	NA	NA	NA	NA
AWR74724.1\|3137911_3138358_+	DUF1320 domain-containing protein	A4JWK2	Burkholderia_virus	2.2e-34	52.3
AWR74725.1\|3138357_3138822_+	hypothetical protein	Q6QIB2	Burkholderia_phage	9.1e-39	51.7
AWR74726.1\|3138818_3139073_+	hypothetical protein	NA	NA	NA	NA
AWR74727.1\|3139062_3140490_+\|tail	phage tail protein	A4JWK5	Burkholderia_virus	4.5e-214	76.3
AWR74728.1\|3140489_3141011_+\|tail	phage major tail tube protein	A4JWK6	Burkholderia_virus	1.8e-67	67.6
AWR74729.1\|3141013_3141295_+	hypothetical protein	NA	NA	NA	NA
AWR74730.1\|3141392_3141728_+\|tail	phage tail assembly protein	NA	NA	NA	NA
AWR74731.1\|3141651_3141810_+\|tail	GpE family phage tail protein	NA	NA	NA	NA
AWR74732.1\|3141885_3144837_+\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	9.8e-86	29.9
AWR74733.1\|3144836_3145721_+	hypothetical protein	A4JWL1	Burkholderia_virus	6.8e-51	47.9
AWR74734.1\|3145717_3145933_+	hypothetical protein	Q6QIA3	Burkholderia_phage	1.2e-17	57.1
AWR74735.1\|3145920_3147075_+	phage protein D	Q6QIA2	Burkholderia_phage	1.9e-85	47.6
AWR74736.1\|3147071_3147668_+\|plate	phage baseplate assembly protein V	A4JWL4	Burkholderia_virus	3.2e-36	45.2
AWR74737.1\|3147722_3148070_+\|plate	baseplate protein	Q6QIA0	Burkholderia_phage	5.9e-35	62.4
AWR74738.1\|3148060_3149164_+\|plate	baseplate protein	Q6QI99	Burkholderia_phage	1.4e-106	55.2
AWR74739.1\|3149156_3149735_+\|tail	phage tail protein I	A4JWL7	Burkholderia_virus	1.7e-66	66.8
AWR74740.1\|3149737_3150985_+\|tail	phage tail protein	A0A0K2FIZ6	Escherichia_phage	2.0e-40	43.7
AWR74741.1\|3150995_3151457_+\|tail	phage tail protein	A0A0F7LCR3	Escherichia_phage	3.9e-34	50.0
AWR74742.1\|3151463_3152078_-\|tail	phage tail protein	Q9MCR5	Enterobacteria_phage	2.5e-60	60.5
AWR74743.1\|3152077_3152602_-\|tail	phage tail protein	A0A0F7LCR3	Escherichia_phage	1.8e-35	48.6
AWR74744.1\|3152661_3153234_+	DNA invertase	A0A0A7NPV4	Enterobacteria_phage	4.6e-85	85.2
AWR74745.1\|3153489_3154773_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
AWR74746.1\|3154843_3155932_-	3-phosphoserine/phosphohydroxythreonine aminotransferase	M1Q1P2	Streptococcus_phage	2.7e-81	46.8
AWR74747.1\|3156130_3156823_-	DUF421 domain-containing protein	NA	NA	NA	NA
AWR74748.1\|3156952_3158713_+	30S ribosomal protein S12 methylthiotransferase accessory protein YcaO	NA	NA	NA	NA
AWR74749.1\|3159118_3159976_+	formate transporter FocA	NA	NA	NA	NA
AWR74750.1\|3160030_3162313_+	formate acetyltransferase 1	A0A2P0VNR5	Tetraselmis_virus	1.0e-162	41.5
AWR74751.1\|3162504_3163245_+	pyruvate formate lyase-activating protein	A0A2P0VNQ0	Tetraselmis_virus	8.0e-21	26.5
AWR74752.1\|3163341_3164490_-	MFS transporter	NA	NA	NA	NA
AWR74753.1\|3164803_3165430_+	hydrolase	NA	NA	NA	NA
AWR74754.1\|3165465_3166329_-	dimethyl sulfoxide reductase anchor subunit	NA	NA	NA	NA
AWR74755.1\|3166330_3166948_-	dimethyl sulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	5.0e-77	60.6
AWR74756.1\|3166958_3169403_-	dimethylsulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	6.6e-221	49.8
3169600:3169619	attL	NA	NA	NA	NA
AWR74757.1\|3169702_3170695_-\|integrase	integrase	A0A0F7LBR0	Escherichia_phage	1.3e-103	56.2
AWR76599.1\|3170764_3171106_-	XRE family transcriptional regulator	Q1JS45	Enterobacteria_phage	4.7e-16	51.2
AWR74758.1\|3171210_3171732_+	transcriptional regulator	NA	NA	NA	NA
AWR74759.1\|3171736_3172159_+	hypothetical protein	NA	NA	NA	NA
AWR74760.1\|3172165_3172357_-	hypothetical protein	NA	NA	NA	NA
AWR74761.1\|3172494_3172845_+	DUF4761 domain-containing protein	A0A0A7NV42	Enterobacteria_phage	8.1e-56	93.1
AWR74762.1\|3172855_3173134_+	hypothetical protein	A0A0A7NRX5	Enterobacteria_phage	3.1e-34	79.3
AWR74763.1\|3173145_3173388_+	DUF4754 domain-containing protein	A0A0A7NQ71	Enterobacteria_phage	2.3e-38	100.0
AWR74764.1\|3173591_3174002_+	hypothetical protein	NA	NA	NA	NA
AWR74765.1\|3174025_3174229_+	hypothetical protein	A0A0A7NPS8	Enterobacteria_phage	2.5e-25	83.6
AWR74766.1\|3174225_3174492_+	MarR family transcriptional regulator	A0A0A7NV47	Enterobacteria_phage	2.0e-30	75.9
AWR74767.1\|3174488_3174788_+	hypothetical protein	A0A0A7NRX6	Enterobacteria_phage	2.4e-40	88.9
AWR74768.1\|3174838_3175054_-	hypothetical protein	NA	NA	NA	NA
AWR74769.1\|3175110_3175341_+	derepression protein	A0A0A7NV48	Enterobacteria_phage	9.1e-32	97.4
AWR74770.1\|3175413_3175779_+	hypothetical protein	A0A0A7NRY1	Enterobacteria_phage	1.7e-61	97.5
AWR76600.1\|3175923_3178608_+	replication endonuclease	A0A0A7NQ77	Enterobacteria_phage	0.0e+00	98.4
AWR74771.1\|3178684_3179644_+	recombinase	A0A0A7NPX4	Enterobacteria_phage	4.2e-179	99.1
AWR74772.1\|3179648_3179963_+	peptide transporter	A0A0A7NPT5	Enterobacteria_phage	4.1e-19	52.3
AWR74773.1\|3180046_3180889_-	hypothetical protein	NA	NA	NA	NA
AWR74774.1\|3180928_3181426_-	DUF4760 domain-containing protein	NA	NA	NA	NA
AWR74775.1\|3182149_3182674_+	hypothetical protein	NA	NA	NA	NA
AWR74776.1\|3182688_3183735_-\|portal	phage portal protein	A0A0A7NPT9	Enterobacteria_phage	2.2e-202	99.7
AWR74777.1\|3183734_3185486_-	oxidoreductase	A0A0A7NV54	Enterobacteria_phage	0.0e+00	97.8
AWR74778.1\|3185640_3186477_+\|capsid	phage capsid protein	A0A0A7NRY7	Enterobacteria_phage	2.7e-150	99.6
AWR74779.1\|3186500_3187553_+\|capsid	phage major capsid protein, P2 family	A0A0A7NQ82	Enterobacteria_phage	1.4e-188	94.3
AWR74780.1\|3187598_3188399_+\|terminase	terminase	A0A0A7NPX9	Enterobacteria_phage	6.9e-127	89.1
AWR74781.1\|3188500_3188995_+\|capsid	capsid assembly protein	A0A0A7NPU2	Enterobacteria_phage	1.9e-87	97.0
AWR74782.1\|3188994_3189195_+\|tail	phage tail protein	A0A0A7NV57	Enterobacteria_phage	3.5e-32	100.0
AWR74783.1\|3189197_3189521_+\|holin	holin	A0A0A7NRY9	Enterobacteria_phage	1.7e-47	93.5
AWR74784.1\|3189517_3189910_+	M15 family peptidase	A0A0A7NQ86	Enterobacteria_phage	1.9e-69	96.9
AWR74785.1\|3189906_3190302_+	DUF2570 domain-containing protein	A0A0A7NPY2	Enterobacteria_phage	1.0e-59	93.3
AWR74786.1\|3190440_3192318_+	DUF1737 domain-containing protein	H6WZJ9	Escherichia_phage	2.7e-299	80.2
AWR74787.1\|3192341_3192809_+\|tail	phage tail protein	A0A0A7NPU6	Enterobacteria_phage	3.5e-83	95.5
AWR74788.1\|3192801_3193437_+	phage virion morphogenesis protein	A0A0A7NV60	Enterobacteria_phage	4.1e-114	99.5
AWR74789.1\|3193433_3194015_+\|plate	phage baseplate assembly protein V	A0A0A7NRZ3	Enterobacteria_phage	3.3e-102	98.4
AWR74790.1\|3194011_3194362_+\|plate	baseplate assembly protein	A0A0A7NQ90	Enterobacteria_phage	3.5e-59	99.1
AWR74791.1\|3194365_3195262_+\|plate	baseplate assembly protein	A0A0A7NPY5	Enterobacteria_phage	3.3e-154	97.7
AWR74792.1\|3195254_3195785_+\|tail	phage tail protein I	A0A0A7NPV1	Enterobacteria_phage	3.6e-92	98.2
AWR74793.1\|3195787_3198010_+\|tail	phage tail protein	A0A0A7NV63	Enterobacteria_phage	3.8e-183	65.0
AWR74794.1\|3198011_3198539_+\|tail	tail fiber assembly protein	A0A0C4UR05	Shigella_phage	2.6e-90	93.7
AWR74795.1\|3198567_3199101_-\|tail	tail fiber assembly protein	C9DGR0	Escherichia_phage	4.2e-96	98.9
AWR74796.1\|3199103_3199661_-\|tail	phage tail protein	A0A0A7NPY7	Enterobacteria_phage	5.0e-84	88.5
AWR74797.1\|3199879_3200479_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	3.8e-98	98.9
AWR74798.1\|3200507_3201002_-\|tail	phage tail protein	A0A0A7NV65	Enterobacteria_phage	2.1e-86	99.4
AWR74799.1\|3201008_3203816_-\|tail	phage tail tape measure protein	A0A0A7NRZ9	Enterobacteria_phage	0.0e+00	90.1
AWR74800.1\|3203802_3204039_-\|tail	GpE family phage tail protein	A0A0A7NQ96	Enterobacteria_phage	4.3e-21	94.1
AWR74801.1\|3203966_3204341_-\|tail	phage tail protein	A0A0A7NPZ0	Enterobacteria_phage	9.9e-36	71.5
AWR74802.1\|3204396_3204909_-\|tail	phage major tail tube protein	A0A0A7NPV8	Enterobacteria_phage	1.5e-90	97.1
AWR74803.1\|3204908_3206093_-\|tail	phage tail sheath family protein	A0A0A7NV69	Enterobacteria_phage	8.4e-222	97.5
AWR74804.1\|3206250_3207360_+	phage late control D family protein	A0A0A7NQ97	Enterobacteria_phage	1.3e-195	94.9
AWR74805.1\|3207400_3207661_+	hypothetical protein	NA	NA	NA	NA
AWR74806.1\|3207852_3207993_+	Hok/Gef family protein	A0A0A7NPZ4	Enterobacteria_phage	1.5e-18	97.8
AWR74807.1\|3208298_3209591_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.5e-94	48.2
3208257:3208276	attR	NA	NA	NA	NA
AWR74808.1\|3209681_3211025_-	recombination factor protein RarA	G3MBE0	Bacillus_virus	3.6e-80	40.8
AWR74809.1\|3211035_3211647_-	outer membrane lipoprotein carrier protein LolA	NA	NA	NA	NA
AWR74810.1\|3211805_3215912_-	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	1.2e-86	48.7
AWR74811.1\|3217083_3218049_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	1.9e-62	44.6
AWR74812.1\|3218171_3219938_+	thiol reductant ABC exporter subunit CydD	W8CYL7	Bacillus_phage	4.1e-23	24.3
AWR74813.1\|3219938_3221660_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	1.2e-14	30.8
AWR74814.1\|3221701_3222406_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
AWR74815.1\|3222690_3222909_+	translation initiation factor IF-1	NA	NA	NA	NA
AWR74816.1\|3223593_3225870_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	1.9e-166	42.5
AWR74817.1\|3225900_3226221_-\|protease	ATP-dependent Clp protease adaptor ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	1.6e-13	44.4

DBSCAN-SWA_8

3983044 : 4026180

Salmonella_phage(25.0%)

transposase,bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWR75516.1\|3983044_3983971_+\|tRNA	tRNA glutamyl-Q(34) synthetase GluQRS	NA	NA	NA	NA
AWR75517.1\|3984009_3985428_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	3.2e-26	37.9
AWR75518.1\|3985424_3985904_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
AWR75519.1\|3986251_3986836_+	fimbrial protein	NA	NA	NA	NA
AWR75520.1\|3986932_3987673_+	fimbrial chaperone	NA	NA	NA	NA
AWR75521.1\|3987707_3990308_+	outer membrane usher protein	NA	NA	NA	NA
AWR75522.1\|3990324_3990897_+	fimbrial protein	NA	NA	NA	NA
AWR75523.1\|3990911_3991544_+	fimbrial protein StaE	NA	NA	NA	NA
AWR75524.1\|3991696_3992959_+\|transposase	IS1380 family transposase ISEc9	A0A1B0VDR3	Salmonella_phage	1.3e-39	100.0
AWR75525.1\|3993208_3994084_+	class A extended-spectrum beta-lactamase CTX-M-14	A0A1B0VBP7	Salmonella_phage	6.1e-153	99.6
AWR75526.1\|3994584_3995181_+	fimbrial protein StaF	NA	NA	NA	NA
AWR75527.1\|3995232_3996486_+	fimbrial protein	NA	NA	NA	NA
AWR75528.1\|3996598_3997393_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	NA	NA	NA	NA
AWR75529.1\|3997404_3998256_+	pantoate--beta-alanine ligase	NA	NA	NA	NA
AWR75530.1\|3998337_3998535_-\|transposase	transposase	NA	NA	NA	NA
AWR75531.1\|3998603_3999524_-\|transposase	ISNCY family transposase	Q2A0A7	Sodalis_phage	4.9e-60	48.8
AWR75532.1\|3999644_3999848_-	hypothetical protein	NA	NA	NA	NA
AWR75533.1\|3999797_4000178_+	aspartate 1-decarboxylase	NA	NA	NA	NA
AWR75534.1\|4000181_4001411_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
AWR75535.1\|4001474_4001915_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
AWR75536.1\|4002019_4002790_-	inner membrane transport permease YadH	NA	NA	NA	NA
AWR75537.1\|4002786_4003713_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.2e-21	34.0
AWR75538.1\|4003821_4004484_+	carbonic anhydrase	NA	NA	NA	NA
AWR75539.1\|4004524_4005061_-	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	5.1e-17	33.1
AWR75540.1\|4005266_4007657_+	glucose/quinate/shikimate family membrane-bound PQQ-dependent dehydrogenase	NA	NA	NA	NA
AWR75541.1\|4007703_4009254_-	multicopper oxidase CueO	A0A0C6DWA2	Mamastrovirus	3.5e-18	55.4
AWR75542.1\|4009419_4009767_+	hypothetical protein	NA	NA	NA	NA
AWR75543.1\|4009872_4010739_+	polyamine aminopropyltransferase	NA	NA	NA	NA
AWR75544.1\|4010754_4011549_+	S-adenosylmethionine decarboxylase proenzyme	NA	NA	NA	NA
AWR75545.1\|4011586_4011949_-	UPF0231 family protein	NA	NA	NA	NA
AWR75546.1\|4012123_4014721_-	aconitate hydratase B	NA	NA	NA	NA
AWR75547.1\|4014701_4014818_-	aconitate hydratase	NA	NA	NA	NA
AWR75548.1\|4015075_4016839_+	DUF3300 domain-containing protein	NA	NA	NA	NA
AWR75549.1\|4016909_4018334_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	4.2e-42	27.8
AWR75550.1\|4018541_4020434_-	pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase	NA	NA	NA	NA
AWR75551.1\|4020448_4023112_-	pyruvate dehydrogenase E1 component	NA	NA	NA	NA
AWR76625.1\|4023093_4023276_+	hypothetical protein	NA	NA	NA	NA
AWR75552.1\|4023272_4024037_-	pyruvate dehydrogenase complex repressor	NA	NA	NA	NA
AWR75553.1\|4024492_4024783_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AWR75554.1\|4024783_4025023_-	hypothetical protein	NA	NA	NA	NA
AWR75555.1\|4025190_4025481_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
AWR75556.1\|4025534_4025723_-	HNH endonuclease	NA	NA	NA	NA
AWR75557.1\|4025889_4026180_-\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA

DBSCAN-SWA_9

4282061 : 4328943

Stx2-converting_phage(23.08%)

transposase,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWR75794.1\|4282061_4283209_-\|transposase	IS3-like element ISEc52 family transposase	Q716C2	Shigella_phage	2.4e-173	96.3
AWR75795.1\|4283371_4283626_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
AWR75796.1\|4284126_4284309_+	hypothetical protein	NA	NA	NA	NA
AWR75797.1\|4286277_4287424_+\|transposase	IS3-like element ISEc52 family transposase	Q716C2	Shigella_phage	2.4e-173	96.3
AWR75798.1\|4288051_4289338_+	restriction endonuclease	NA	NA	NA	NA
AWR75799.1\|4289447_4291187_+	Alw26I/Eco31I/Esp3I family type II restriction endonuclease	NA	NA	NA	NA
AWR75800.1\|4291199_4292390_-	DNA cytosine methyltransferase	Q02778	Bacillus_phage	7.3e-16	31.0
AWR75801.1\|4292382_4294023_-	Alw26I/Eco31I/Esp3I family type II restriction adenine-specific DNA-methyltransferase	NA	NA	NA	NA
AWR75802.1\|4295593_4295770_-	DUF957 domain-containing protein	NA	NA	NA	NA
AWR75803.1\|4295786_4296275_-	hypothetical protein	NA	NA	NA	NA
AWR75804.1\|4296271_4296649_-	toxin	NA	NA	NA	NA
AWR75805.1\|4296738_4297107_-	antitoxin	NA	NA	NA	NA
AWR75806.1\|4297269_4297491_-	DUF987 domain-containing protein	A0A142F0X9	Klebsiella_phage	1.9e-10	45.8
AWR76635.1\|4297553_4298000_-	hypothetical protein	NA	NA	NA	NA
AWR75807.1\|4298045_4298519_-	antirestriction protein	A9J566	Pseudomonas_phage	8.7e-13	30.3
AWR75808.1\|4298860_4299679_-	DUF945 domain-containing protein	A0A2C9CX26	Yersinia_phage	9.4e-47	39.7
AWR75809.1\|4299699_4299834_-	cytoplasmic protein	NA	NA	NA	NA
AWR75810.1\|4299833_4300028_-	DUF905 domain-containing protein	NA	NA	NA	NA
AWR75811.1\|4300062_4302909_-	autotransporter adhesin Ag43	NA	NA	NA	NA
AWR75812.1\|4303281_4304154_-	50S ribosome-binding GTPase	NA	NA	NA	NA
AWR75813.1\|4304238_4305156_-	hypothetical protein	NA	NA	NA	NA
AWR75814.1\|4305288_4305504_+	hypothetical protein	NA	NA	NA	NA
AWR75815.1\|4305987_4306185_-	hypothetical protein	NA	NA	NA	NA
AWR76636.1\|4306253_4306451_+	hypothetical protein	NA	NA	NA	NA
AWR75816.1\|4306356_4306974_-	hypothetical protein	NA	NA	NA	NA
AWR75817.1\|4307054_4307315_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
AWR75818.1\|4307257_4307464_-	hypothetical protein	NA	NA	NA	NA
AWR75819.1\|4308034_4308184_+	hemolysin activation protein	NA	NA	NA	NA
AWR75820.1\|4308203_4308404_+	hypothetical protein	NA	NA	NA	NA
AWR75821.1\|4308516_4308714_-	hypothetical protein	NA	NA	NA	NA
AWR75822.1\|4308877_4309483_+	inovirus Gp2 family protein	NA	NA	NA	NA
AWR75823.1\|4309736_4310144_+	hypothetical protein	NA	NA	NA	NA
AWR75824.1\|4310044_4310566_+	hypothetical protein	NA	NA	NA	NA
AWR75825.1\|4310565_4310802_+	hypothetical protein	NA	NA	NA	NA
AWR75826.1\|4310920_4311301_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBP6	Stx2-converting_phage	7.1e-66	99.2
AWR75827.1\|4311297_4311645_+	IS66 family insertion sequence hypothetical protein	A0A0P0ZBY2	Stx2-converting_phage	2.2e-61	100.0
AWR75828.1\|4311694_4313080_+\|transposase	IS66 family transposase	A0A0P0ZBS5	Stx2-converting_phage	3.4e-259	89.3
AWR75829.1\|4313318_4314692_-	esterase-like activity of phytase family protein	NA	NA	NA	NA
AWR75830.1\|4316238_4316760_+	RNA polymerase sigma factor FecI	NA	NA	NA	NA
AWR75831.1\|4316756_4317710_+	protein FecR	NA	NA	NA	NA
AWR75832.1\|4317796_4320121_+	fe(3+) dicitrate transporter fecA	NA	NA	NA	NA
AWR75833.1\|4320165_4321068_+	Fe(3+)-dicitrate ABC transporter substrate-binding protein FecB	NA	NA	NA	NA
AWR75834.1\|4321064_4322063_+	Fe3+ dicitrate ABC transporter permease	NA	NA	NA	NA
AWR75835.1\|4322059_4323016_+	iron-dicitrate transporter subunit FecD	A0A2H4IY97	uncultured_Caudovirales_phage	1.1e-17	26.1
AWR75836.1\|4323016_4323784_+	Fe(3+) dicitrate transport ATP-binding protein FecE	G3M9Y6	Bacillus_virus	6.4e-13	24.8
AWR75837.1\|4324340_4324754_-	hypothetical protein	NA	NA	NA	NA
AWR75838.1\|4325531_4326687_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	3.6e-68	45.1
AWR75839.1\|4326836_4328840_+\|holin	high-affinity choline transporter BetT	A0A2I7QNT1	Vibrio_phage	4.4e-21	25.9
AWR75840.1\|4328784_4328943_+\|holin	choline transporter	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP028484

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP028483

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection