CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP029653	Staphylococcus aureus strain AR_0470 chromosome, complete genome	12 crisprs	cas1,cas2,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,csm6,cas6,csa3,cas3,DEDDh,DinG,WYL	5	13	12	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP029653_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_1

61276-62170

TypeIII

Consensus_repeat	Method
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	PILER-CR
GATCGATAACTACCCCGAATAACAGGGGACGAGAATT	CRISPRCasFinder
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	CRT

12 spacers

cas1,cas2,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,csm6,cas6

The CRISPR arrays of CP029653_1

>merge|CP029653|1|61276-62170|PILER-CR,CRISPRCasFinder,CRT
GATCGATAACTACCCCGAATAACAGGGGACGAGAATACTTCTCTCGCCATTTCTGCTAATTGTTCTACTTTGGATCGATAACTACCCCGAATAACAGGGGACGAGAATTCTATAAGTTCATTAATTCCGATACCTAGATTATCTGATCGATAACTACCCCGAATAACAGGGGACGAGAATTTTTTTCCACCCTTTCAGATCATCTATGATCTTGGATCGATAACTACCCCGAATAACAGGGGACGAGAATTCTGTAATGTATTCATTTAATGTAATCATAATTTTTTCGATCGATAACTACCCCGAATAACAGGGGACGAGAATTAGACCATTTACCTCATTATATTTATAGTCTTTATTAGATCGATAACTACCCCGAATAACAGGGGACGAGAATTTTTCTTTAACTGTTTTTACTGCCCATTTAATAGTGATCGATAACTACCCCGAATAACAGGGGACGAGAATATAAACCCGTTCAATTCGTTATCTTTAAATTCTTGGATCGATAACTACCCCGAATAACAGGGGACGAGAATACAACTTCGTCATCTTTCATCATTTCTCTTACATCAGATCGATAACTACCCCGAATAACAGGGGACGAGAATATATTTCTTCCATGAATAACACCCTCCTTTTTTCTAGATCGATAACTACCCCGAATAACAGGGGACGAGAATAAGTTAACGGCATTACCTAATAAAAATATTTTAGGGATCGATAACTACCCCGAATAACAGGGGACGAGAACTCATCTTTCATGTCACTGATTAATTCATTTGTAGATCGATAACTACCCCGAATAACAGGGGACGAGAACGGTAATAGTTGCTCAATAGGTAATAAAACGTCGGTGATCGATAACTATCCCGAATAACAGGGGACAGAGTGT

>CP029653|1|1|61276-62097|PILER-CR
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TACTTCTCTCGCCATTTCTGCTAATTGTTCTACTTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TTCTATAAGTTCATTAATTCCGATACCTAGATTATCT
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TTTTTTTCCACCCTTTCAGATCATCTATGATCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TTCTGTAATGTATTCATTTAATGTAATCATAATTTTTTC
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TTAGACCATTTACCTCATTATATTTATAGTCTTTATTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TTTTTCTTTAACTGTTTTTACTGCCCATTTAATAGT
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TATAAACCCGTTCAATTCGTTATCTTTAAATTCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TACAACTTCGTCATCTTTCATCATTTCTCTTACATCA
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TATATTTCTTCCATGAATAACACCCTCCTTTTTTCTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	TAAGTTAACGGCATTACCTAATAAAAATATTTTAGG
GATCGATAACTACCCCGAATAACAGGGGACGAGAA	CTCATCTTTCATGTCACTGATTAATTCATTTGTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAA

>CP029653|1|1|61276-62170|CRISPRCasFinder
GATCGATAACTACCCCGAATAACAGGGGACGAGAATA	CTTCTCTCGCCATTTCTGCTAATTGTTCTACTTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAATT	CTATAAGTTCATTAATTCCGATACCTAGATTATCT
GATCGATAACTACCCCGAATAACAGGGGACGAGAATT	TTTTTCCACCCTTTCAGATCATCTATGATCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAATT	CTGTAATGTATTCATTTAATGTAATCATAATTTTTTC
GATCGATAACTACCCCGAATAACAGGGGACGAGAATT	AGACCATTTACCTCATTATATTTATAGTCTTTATTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAATT	TTTCTTTAACTGTTTTTACTGCCCATTTAATAGT
GATCGATAACTACCCCGAATAACAGGGGACGAGAATA	TAAACCCGTTCAATTCGTTATCTTTAAATTCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAATA	CAACTTCGTCATCTTTCATCATTTCTCTTACATCA
GATCGATAACTACCCCGAATAACAGGGGACGAGAATA	TATTTCTTCCATGAATAACACCCTCCTTTTTTCTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAATA	AGTTAACGGCATTACCTAATAAAAATATTTTAGG
GATCGATAACTACCCCGAATAACAGGGGACGAGAACT	CATCTTTCATGTCACTGATTAATTCATTTGTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAACG	GTAATAGTTGCTCAATAGGTAATAAAACGTCGGT
GATCGATAACTATCCCGAATAACAGGGGACAGAGTGT

>CP029653|1|1|61276-62169|CRT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ACTTCTCTCGCCATTTCTGCTAATTGTTCTACTTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TCTATAAGTTCATTAATTCCGATACCTAGATTATCT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TTTTTTCCACCCTTTCAGATCATCTATGATCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TCTGTAATGTATTCATTTAATGTAATCATAATTTTTTC
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TAGACCATTTACCTCATTATATTTATAGTCTTTATTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	TTTTCTTTAACTGTTTTTACTGCCCATTTAATAGT
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ATAAACCCGTTCAATTCGTTATCTTTAAATTCTTG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ACAACTTCGTCATCTTTCATCATTTCTCTTACATCA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	ATATTTCTTCCATGAATAACACCCTCCTTTTTTCTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAT	AAGTTAACGGCATTACCTAATAAAAATATTTTAGG
GATCGATAACTACCCCGAATAACAGGGGACGAGAAC	TCATCTTTCATGTCACTGATTAATTCATTTGTA
GATCGATAACTACCCCGAATAACAGGGGACGAGAAC	GGTAATAGTTGCTCAATAGGTAATAAAACGTCGGT
GATCGATAACTATCCCGAATAACAGGGGACAGAGTG

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ87497.1\|60422_60554_-\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ88378.1\|66899_67733_+\|putative-cRISPR-associated-RAMP-protein	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|273866
CP029653.1\|AWQ89000.1\|59193_59505_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368760
CP029653.1\|AWQ88869.1\|67735_68758_+\|RAMP-superfamily-protein	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
CP029653.1\|AWQ88703.1\|60550_60811_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378743
CP029653.1\|AWQ88241.1\|63147_63453_+\|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09638_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|273699
CP029653.1\|AWQ88604.1\|54784_55153_+\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ89717.1\|58761_59100_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368749
CP029653.1\|AWQ87532.1\|70022_70757_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
CP029653.1\|AWQ87535.1\|60037_60259_+\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ88332.1\|55152_56769_+\|putative-cassette-chromosome-recombinase	unknown	unknown	gnl\|CDD\|225913
CP029653.1\|AWQ88018.1\|71866_72025_+\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ87378.1\|63466_65740_+\|HD-domain-protein	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
CP029653.1\|AWQ89214.1\|56993_58673_+\|resolvase,-N-terminal-domain-protein	unknown	unknown	gnl\|CDD\|214861
CP029653.1\|AWQ89879.1\|59519_60023_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226783
CP029653.1\|AWQ89507.1\|53682_54792_+\|DNA-polymerase-A-family-protein	unknown	unknown	gnl\|CDD\|237876
CP029653.1\|AWQ89263.1\|68757_70026_+\|CRISPR-associated-family-protein	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|131720
CP029653.1\|AWQ88722.1\|62242_63148_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
CP029653.1\|AWQ89239.1\|66169_66814_+\|RAMP-superfamily-protein	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
CP029653.1\|AWQ88866.1\|65742_66168_+\|hypothetical-protein	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|273844

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ89717.1\|58761_59100_+\|hypothetical-protein	gnl\|CDD\|368749	pfam06106, SAUGI, S. aureus uracil DNA glycosylase inhibitor. Uracil-DNA glycosylase inhibitors, are DNA mimic proteins that prevent the DNA binding sites of UDGs (Uracil DNA glycosylase) from interacting with their DNA substrate. SSP0047 (SAUGI; for Staphylococcus aureus uracil-DNA glycosylase inhibitor) acts as a uracil-DNA glycosylase inhibitor that breaks the uracil-removing activity of S. aureus uracil-DNA glycosylase (SAUDG) pfam03167. The SAUGI/SAUDG complex has been determined, and shows that SAUGI binds to the SAUDG DNA binding region via several strong interactions, by using a hydrophobic pocket to hold SAUDG's protruding residue (i.e. SAUDG Leu184, E. coli UDG Leu191 and B. subtilis UDG Phe191). By binding to SAUDG in this way, SAUGI thus prevents SAUDG from binding to its DNA substrate and performing DNA repair activity.	8.57061e-38
CP029653.1\|AWQ88378.1\|66899_67733_+\|putative-cRISPR-associated-RAMP-protein	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	4.83771e-38
CP029653.1\|AWQ89000.1\|59193_59505_+\|hypothetical-protein	gnl\|CDD\|368760	pfam06124, DUF960, Staphylococcal protein of unknown function (DUF960). This family consists of several hypothetical proteins from several species of Staphylococcus. The function of this family is unknown.	6.74747e-26
CP029653.1\|AWQ88869.1\|67735_68758_+\|RAMP-superfamily-protein	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.06095e-17
CP029653.1\|AWQ88703.1\|60550_60811_-\|hypothetical-protein	gnl\|CDD\|378743	pfam11867, DUF3387, Domain of unknown function (DUF3387). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is typically between 255 to 340 amino acids in length. This domain is found associated with pfam04851, pfam04313.	3.1971e-31
CP029653.1\|AWQ88241.1\|63147_63453_+\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|273699	TIGR01573, cas2, CRISPR-associated endonuclease Cas2. This model describes most members of the family of Cas2, one of the first four protein families found to mark prokaryotic genomes that contain multiple CRISPR elements. CRISPR systems protect against invasive nucleic acid sequences, including phage. Cas2 proteins have been characterized as either endoribonuclease (for ssRNA) or endodeoxyribonuclease (for dsDNA), depending on the system to which the Cas2 belongs. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats. The cas genes usually are found near the repeats. A distinct branch of the Cas2 family shows a very low level of sequence identity and is modeled by TIGR01873 instead of by this model (TIGR01573).	4.06918e-22
CP029653.1\|AWQ89214.1\|56993_58673_+\|resolvase,-N-terminal-domain-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	6.7072e-34
CP029653.1\|AWQ87532.1\|70022_70757_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	7.10684e-15
CP029653.1\|AWQ88332.1\|55152_56769_+\|putative-cassette-chromosome-recombinase	gnl\|CDD\|225913	COG3378, COG3378, Phage associated DNA primase [General function prediction only].	3.31891e-21
CP029653.1\|AWQ87378.1\|63466_65740_+\|HD-domain-protein	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
CP029653.1\|AWQ88722.1\|62242_63148_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.00185e-113
CP029653.1\|AWQ89879.1\|59519_60023_+\|hypothetical-protein	gnl\|CDD\|226783	COG4333, COG4333, Uncharacterized protein conserved in bacteria [Function unknown].	1.3268e-79
CP029653.1\|AWQ89507.1\|53682_54792_+\|DNA-polymerase-A-family-protein	gnl\|CDD\|237876	PRK14975, PRK14975, bifunctional 3'-5' exonuclease/DNA polymerase; Provisional.	1.53397e-08
CP029653.1\|AWQ89263.1\|68757_70026_+\|CRISPR-associated-family-protein	gnl\|CDD\|131720	TIGR02672, hypothetical_protein_SERP2456, CRISPR type III-A/MTUBE-associated protein Csm6. Members of this family as found in CRISPR-associated (cas) gene regions in Streptococcus thermophilus CNRZ1066, Staphylococcus epidermidis RP62A, and Mycobacterium tuberculosis (strains CDC1551 and H37Rv), as part of Mtube-type CRISPR/Cas systems. CRISPR is a widespread form of direct repeat found in archaea and bacteria, with distinctive subtypes each of which has a characteristic sporadic distribution.	1.16357e-132
CP029653.1\|AWQ88866.1\|65742_66168_+\|hypothetical-protein	gnl\|CDD\|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	7.59929e-21
CP029653.1\|AWQ89239.1\|66169_66814_+\|RAMP-superfamily-protein	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	7.36094e-106

>CP029653.1|AWQ88703.1|60550_60811_-|hypothetical-protein
MAVELLNRLLKGQVKSLMKTNATVSKRFSEMLRNSINKYNSRSIETSKVIEELIQLAKDIKQEQQRGNELGLNSDEIAFLRCFSFT
>CP029653.1|AWQ87497.1|60422_60554_-|hypothetical-protein
MKQRKKGMEDEELRAIAHELTKKVKENMGVIGLNVIAQKLKCA
>CP029653.1|AWQ87535.1|60037_60259_+|hypothetical-protein
MNHETTHSDWRTVANCLASQNYISIVKGLVHHFTAIEDEEILDKIYEDFMNNGSITTVLNNDLQDIINYYLSK
>CP029653.1|AWQ89879.1|59519_60023_+|hypothetical-protein
MNTIKSTIHTEAIFSDDEQHRYLLKKTWDEKKPVCTVITMYPHLDGVLSLDLTTVLILNQLANSEQYGAVYLVNLFSNIKTPENLKHIKEPYDKHTDIHLMKAISESDTVILAYGAYAKRPVVVERVEQVMEMLKPHKKKVKKLINPATNDIMHPLNPKARQKWILK
>CP029653.1|AWQ89000.1|59193_59505_+|hypothetical-protein
MNINRYITRGISEQLSLDLQILLWHMVEEKDNQPHTDYLHIFKLQEDDNMLSITHEQEQPAYKLEYHYINYEKNQNALPKKVYVIREDDVDVFYYVMLLPEEY
>CP029653.1|AWQ89717.1|58761_59100_+|hypothetical-protein
MTLSKQLKTYITERFKLNYQETWACETIDAVAEDVLPEKYIKNSPLEHKILNTFTYYNDELHEISIYPFLCYLDKELVAIGYLDNFDLDFIFLNDTHQIIIDERYLLQKGGE
>CP029653.1|AWQ89214.1|56993_58673_+|resolvase,-N-terminal-domain-protein
MKGKIALYSRVSTSEQSEHGYSEKEQEQLLIKEVMKNFPGYDYETYTDSGISGKNIEGRPAMKRLLQDVKDNKIEMVLSWKLNRISRSMRDVFNIIHEFKEHDVGYKSISENIDTSNASGEVLVTMFGLIGSIERQTLISNVKLSMNAKARSGEAITGRVLGYKLSLNPLTQKNDLVIDENEAHIVREIFDLYLNHNKGFKAITTILNQKGYRTINQKPFSVFGVKYILNNPVYKGYVRFNNHQNWAVQRRSGKSDKNDVILVKGKHEAIISEDVFDQVHEKLASKSFKPGRPIGGDFYLRGLIKCPECGNNMVCRRTYYKTKKSKERTIKRYYICSLFNRSGSSACHSNAINAEVVERVINVHLNRILSQPNVIKQIASSVIEELKQKHSKQTEIKYDIDSLEKQKAKVKTQQERLLELFLDDEMDSEMLKAKQSEMNQQLEVLDQQIKEAKQANQSQDDIPNFDKLKARLILMITRFSVYLRKATPEAKNQLMKMLIDSIEITTDKQVKLVRYKIDESLIPQSLKKDWGSFFIPKFNFVINVTKKNRIENLSLLPLF
>CP029653.1|AWQ88332.1|55152_56769_+|putative-cassette-chromosome-recombinase
MNHILEMLIKLLKVGMEAIDRKGLIAILTSSIGNDEMDDSEQAVMVYNELIDKLQLNIPKDVDYRPNIYSYFGIQKKPNDTILVEMMICIFHIKRFDSELFVFKDKGWQKVSEDELQGLISKMIQVLLVDYKPSLSTLKNVVDGIQKSTDIEKLVEHRQYIGCGRNMFNLKTFKVVDNDLEIFPKTRLDLELDINDTITDKIPPNFKQYMLELANYDHDLQYFLFQHMAVLLTADTKLRRGLFLYGTAKNGKSVYIKLVKSFFYSNDIVSKTLNELGGRFDKESLIGKRIMASDEVGKANIDEATVNDFKKLLSVEPIHADRKGRTQVEVTLDLKLIFNTNAVLNFPSSHAKALERRIAVIPCEYYVEKADPDLIEKLQDEKKEIFLYLMYVYKQIVKNDIEYLQNDRVTEISHDWLNFGYEFVSSKSANIAHQKACINLLRKLIEIKPGSRIKVSRLNEVIRDEIKVSSQVINDLVQANFNVQSRLNNGYKYWVDLGWKETDKKDDMISFDKNENVTDDEFLYEDDLNLGWEDFDDE
>CP029653.1|AWQ88604.1|54784_55153_+|hypothetical-protein
MNNDRGKSLQIPQSTLLKEGSIYVATLHSVYEKNFSGDIKHQFTYEVELNQETHYVNRNITVKSMSHQLSIADWIKRHSNYNVNHINYDPYIDRKHLVLVGQYNGNYYIQDVAPLDEFGGVL
>CP029653.1|AWQ89507.1|53682_54792_+|DNA-polymerase-A-family-protein
MYQANIRDLITKLPQSNKTEHFLMNKFSNQDKVQQLQRQISQQLDQQYNELLANEKAKLDQYVEVHHNLEPLKKEIESESINLDTDKLPDIKATMLEKAKNDEHFDKIEQLFDRLDQSLNGTNRLYTQLSLIGTRTHRITTKRFNVQGLPKLVQQMILPSQFKKVYTIDFKSFEPSVAAYMTQDEQLIDYLNHEEGLYDALLRDLSLSKEKRVSVKRAFIGSFLFGGRYSSSKFKINQEVSEINWLQVMSKFKKVIEFKEQVEKYKTMPTPYGIEHDMSAFQGSSIMAIYVQTVASYIFKHILLEVYKAQCEKKTFKIIVPIHDAIMIECNDKGIAQNVAQLMKDTANQLFNGEFAHVTVEALGGIDNE
>CP029653.1|AWQ88722.1|62242_63148_+|CRISPR-associated-endonuclease-Cas1
MKDVIYVENHYFVTVKENSIKFRNVIDKSEKFYLFEEIEAIIFDHYKSYFSHKLVIKCIENDIAIIFCDKKHSPLTQLISSYGMTHRLQRIQSQFQLSGRTRDRIWKKIVVNKIINQSKCLENNLHNENVKLLVNLAKDVSSGDKSNKEAQAARIYFKDLYGKQFKRGRYNDIINSGLNYGYSILRSFIKKELALHGFEMSLGINHRSKENPFNLADDIIEVFRPFVDNIVYEIVFKKNINTFDVNEKKLLLNVLYEKCIIDKKVVRLLDSVKIVIQSLIRCYEENTPTYLLLPKMIEVGN
>CP029653.1|AWQ88241.1|63147_63453_+|CRISPR-associated-endoribonuclease-Cas2
MYLLVSFDLPRDTKFERRVASKYRTRLLELGFSMKQFSLYERYVSDVQKKDKILEILQQEIPDTGSITLYVLPDEVNNSQITILGKEVKVVVRKEPKLIFL
>CP029653.1|AWQ87378.1|63466_65740_+|HD-domain-protein
MDKKTTLMYGSLLHDIGKIIYRSNDHAFARGTHSKLGYNFLSQFSEFKDNEVLDSIAYHHYKELAKANLANDNTAYITYIADNIASGIDRRDVIEEGDEEYEKQAFNFDKYTPLYSVFNIVNSEKLKQISGKFKFSNESNIEYPKTENIQYSSGNYTTLMKDMSYDLEHKLSIKEDTFPSLLQWTESLWQYVPSSTNKNQLIDISLYDHSRITCAIASCIFDYLNENNIHNYKDELFTKYENTKEFYQKEAFLLLSMDMSGIQDFIYNISGSKALKSLRSRSFYLEIMLEVIVDQLLEKLELTRANLLYTGGGHAYLLVSNTDKGKEKINQFNTELKNWFMSEFTTDLSLSIAFEKCSGNDLMNTSGNYRNIWRNVSSKLSDIKAHKYSSEDILKLNHFHSYGDRECKECLRSDIDINDDGLCSICEGIINISNDLRDKSFFVLSETGKLKMPFDKFISVIDYEEAERLAQNNNHIRIYSKNKPYIGVGISTNLWMCDYDYASQNKDMREKGIGSYVEREEGIKRLGVVRADIDNLGATFISGIPEKYNSISRTATLSRQLSLFFKYELNHLLENYQITAIYSGGDDLFLIGAWDDIIEVSVYINEKFKDFTLGKLTMSAGVGMFSGKYPISKMAFETGLLEEAAKTDEKNQIALWVQEKVYNWDEFKKYILEEKLLVLQHGFSQTDEHGKAFIYKMLALLRNNETINIARLAYLLARSKMTEEFTSKIFNWAQNDKDKNQLITALEYYVYQIREVD
>CP029653.1|AWQ88866.1|65742_66168_+|hypothetical-protein
MILAKTKSGKKIDLTFAHEVVKSNVKTVKDKRGKENQVLFNGLTTSKLRNLMEQVNRLYTIAFNSTEDQLNEEFIDELEYLKIKFYYEAGREKSVDEFLKKTLMFPIIDRVIQKESKKFFLDYCKYFEALVAYAKYYQKED
>CP029653.1|AWQ89239.1|66169_66814_+|RAMP-superfamily-protein
MYSKIKISGTIEVVTGLHIGGGGESSMIGAIDSPVVRDLQTKLPIIPGSSIKGKMRSLLAKHFGLKMKQENHNQDDESVLRLFGSSEKGNIQRARLQISDAFFSEKTKEHFAQNDIAYTETKFENTINRLTAVANPRQIERVTRGSEFDFVFIYNVDEESQVENDFENIEKAIHLLENDYLGGGGTRGNGRIQFNDITIETVVGEYDSTNLKIK
>CP029653.1|AWQ88378.1|66899_67733_+|putative-cRISPR-associated-RAMP-protein
MTITSDTLFSALFIEALQLGIETDWLLNDLIISDTFPYENEIYYLPKPLIKIESKEEGNHKAFKKLKYVPVHHYNQYLNGELSAEDATDLNDIFSIGHFSLQTKVSLSAQEIDSSADSEPYSVGTFTFEPEAGLYFIAKGSEETLDQLKDIMTSLQYSGLGGKRNAGYGQFEYEIINNQQLFKLLNQNGEHSILLSTAMAKEDEIKSALKEARYILNKRSGFIQSTNYSEMLVKKSDFYSFSSGSVFKNIFNGDVFNVGHNGKHPVYRYAKPLWLEV
>CP029653.1|AWQ88869.1|67735_68758_+|RAMP-superfamily-protein
MTIKNYEVVIKTLGPVHIGSGQVMKKQDYIYDFYNSKVYMINGNKLVKFLKRKNILDTYQNFLRYPPKNPRENGLKDYLDAQNVKQSEWKAFVSYSEKVNQGKKYGNIRPKPLNDLHLMVRDGQNKVYLPGSSIKGAIKTALVSKYNNEKNTDVYSKIKVSDSEPIDERHLAIYQKIDINKSEKPMPLYRECVDVDTEIKFKLTIEDEIYSINEIEQSIQDFYKNYYDKWLVGFKETKGGRRFALEGGMPDVLNQNILFLGAGAGFVSKTTHYQLKSREQAKRDSFDILTKKFRRTYGKMKEMPSNVPVALKGTTNQSLHVSYQQGMCKISFQELNNEVL
>CP029653.1|AWQ89263.1|68757_70026_+|CRISPR-associated-family-protein
MKVLFSPIGNSDPWSNDRDGAMLHIVRHYKPDVVVLFFTESIWNGNRNIPGRKNFDWENIVSKVSSRTKVDIKVDSIKYENDFDSYKDIFHFYINEIRTKYSDAEILLNVTSGTPQMESTLCLEYISNPHNMKCIQVSTPAPIEGPKRSFAKLETVTEDLNKVNANEKMASNRSKSINIISFREVMVRSQIKSLVNNYDYEGALNLVSDQKSFRNGKLLRKRLLELTNQIKTHEVFPEINDKYRSVALKKSLFHYLLLNMRYNRLDVAETLIRVKSIAEFILKTYIVGHWPTLIIEKDDKPYLNAEDNLSFIYKYKLLLEKRRQNLDVSRILGLPAFIDILTVLEPNSKLLKEVNAVNDINGLRNSIAHNLETLDLDKNKNYKKIMLSVEAIKNMLHISFPEIEEKDYNYFERKNKEFRELL
>CP029653.1|AWQ87532.1|70022_70757_+|CRISPR-associated-endoribonuclease-Cas6
MINKITVELDLPDSIRFQYLGSILHGVLMDYLPNDIADQLHHEFAYSPLKQRIYHKNKKVIWEIVCMSDRLFNEIAELFTSKNRLFLKYYQVYIEIYSFNIEKVNVQNIMNQLLETEELNRYVRINIQTPMSFKYQSNYMIFPEVKRFFRSIMIQFDAFFEEYKMYDKETLDFLEKNINIVDYKLKSTRFNLEKVKIPSFTGEIVFKIKGPLPFLQLTHFLLKFGEFSGSGMKTSLGMGKYSII
>CP029653.1|AWQ88018.1|71866_72025_+|hypothetical-protein
MKFKSKQLVIANQTKVINYRIQVLLKPQANIETQTQVKNNTLPETDEQSNAD

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Crispr_ID: CP029653_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_2

70892-71139

TypeIII

Consensus_repeat	Method
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG	CRISPRCasFinder
ATTCGATAACTACCNCCGTAGAAGAGGGGACGAG	CRT

3 spacers

cas6,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas2,cas1,csa3

The CRISPR arrays of CP029653_2

>merge|CP029653|2|70892-71139|CRISPRCasFinder,CRT
ATTCGATAACTACCCCGTAGAAGAGGGGACGAGAACTCTTCTAAGACGCGATATGATTCTAATTGGTCTTCATTCGATAACTACCCCCGTAGAAGAGGGGACGAGAACTGATATACTCCTTTACCATGTATTAATTCTGGACCACTATTCGATAACTACCCCGTAGAAGAGGGGACGAGAACTCATATTCGATCGTGTATATCAAAACTTTATGCATTCGATAACTACCCCGTAGAAGAGGGGACGAG

>CP029653|2|2|70892-71139|CRISPRCasFinder
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG	AACTCTTCTAAGACGCGATATGATTCTAATTGGTCTTCA
TTCGATAACTACCCCCGTAGAAGAGGGGACGAG	AACTGATATACTCCTTTACCATGTATTAATTCTGGACCACT
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG	AACTCATATTCGATCGTGTATATCAAAACTTTATGC
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG

>CP029653|2|2|70892-71139|CRT
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG	AACTCTTCTAAGACGCGATATGATTCTAATTGGTCTTC
ATTCGATAACTACCCCCGTAGAAGAGGGGACGA	GAACTGATATACTCCTTTACCATGTATTAATTCTGGACCACT
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG	AACTCATATTCGATCGTGTATATCAAAACTTTATGC
ATTCGATAACTACCCCGTAGAAGAGGGGACGAG

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ89872.1\|72206_72584_+\|DDE-domain-protein	unknown	unknown	gnl\|CDD\|225853
CP029653.1\|AWQ88869.1\|67735_68758_+\|RAMP-superfamily-protein	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
CP029653.1\|AWQ88378.1\|66899_67733_+\|putative-cRISPR-associated-RAMP-protein	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|273866
CP029653.1\|AWQ89838.1\|77520_78534_+\|transposase-IS116/IS110/IS902-family-protein	unknown	unknown	gnl\|CDD\|376773
CP029653.1\|AWQ88703.1\|60550_60811_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378743
CP029653.1\|AWQ88241.1\|63147_63453_+\|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09638_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|273699
CP029653.1\|AWQ87615.1\|72611_72989_-\|signal-peptidase-II	unknown	unknown	gnl\|CDD\|234739
CP029653.1\|AWQ87378.1\|63466_65740_+\|HD-domain-protein	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
CP029653.1\|AWQ87532.1\|70022_70757_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
CP029653.1\|AWQ89239.1\|66169_66814_+\|RAMP-superfamily-protein	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
CP029653.1\|AWQ88018.1\|71866_72025_+\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ89521.1\|80730_82152_+\|dihydrolipoyl-dehydrogenase	unknown	unknown	gnl\|CDD\|235798
CP029653.1\|AWQ88722.1\|62242_63148_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
CP029653.1\|AWQ89587.1\|74900_77075_+\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319845
CP029653.1\|AWQ89263.1\|68757_70026_+\|CRISPR-associated-family-protein	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|131720
CP029653.1\|AWQ88866.1\|65742_66168_+\|hypothetical-protein	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|273844
CP029653.1\|AWQ89975.1\|73876_74644_+\|ZIP-Zinc-transporter-family-protein	unknown	unknown	gnl\|CDD\|223505
CP029653.1\|AWQ89596.1\|73221_73623_+\|cadmium-resistance-transcriptional-regulatory-protein-CadC	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|236654
CP029653.1\|AWQ89739.1\|78630_80310_-\|transposase-DDE-domain-protein	unknown	unknown	gnl\|CDD\|226192
CP029653.1\|AWQ87591.1\|82379_83042_+\|cadmium-resistance-transporter-family-protein	unknown	unknown	gnl\|CDD\|129861

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ89872.1\|72206_72584_+\|DDE-domain-protein	gnl\|CDD\|225853	COG3316, COG3316, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.16386e-31
CP029653.1\|AWQ88869.1\|67735_68758_+\|RAMP-superfamily-protein	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.06095e-17
CP029653.1\|AWQ88378.1\|66899_67733_+\|putative-cRISPR-associated-RAMP-protein	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	4.83771e-38
CP029653.1\|AWQ89838.1\|77520_78534_+\|transposase-IS116/IS110/IS902-family-protein	gnl\|CDD\|376773	pfam02371, Transposase_20, Transposase IS116/IS110/IS902 family. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS116, IS110 and IS902. This region is often found with pfam01548. The exact function of this region is uncertain. This family contains a HHH motif suggesting a DNA-binding function.	2.72185e-20
CP029653.1\|AWQ88703.1\|60550_60811_-\|hypothetical-protein	gnl\|CDD\|378743	pfam11867, DUF3387, Domain of unknown function (DUF3387). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is typically between 255 to 340 amino acids in length. This domain is found associated with pfam04851, pfam04313.	3.1971e-31
CP029653.1\|AWQ88241.1\|63147_63453_+\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|273699	TIGR01573, cas2, CRISPR-associated endonuclease Cas2. This model describes most members of the family of Cas2, one of the first four protein families found to mark prokaryotic genomes that contain multiple CRISPR elements. CRISPR systems protect against invasive nucleic acid sequences, including phage. Cas2 proteins have been characterized as either endoribonuclease (for ssRNA) or endodeoxyribonuclease (for dsDNA), depending on the system to which the Cas2 belongs. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats. The cas genes usually are found near the repeats. A distinct branch of the Cas2 family shows a very low level of sequence identity and is modeled by TIGR01873 instead of by this model (TIGR01573).	4.06918e-22
CP029653.1\|AWQ87615.1\|72611_72989_-\|signal-peptidase-II	gnl\|CDD\|234739	PRK00376, lspA, lipoprotein signal peptidase.	2.70108e-40
CP029653.1\|AWQ87378.1\|63466_65740_+\|HD-domain-protein	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
CP029653.1\|AWQ87532.1\|70022_70757_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	7.10684e-15
CP029653.1\|AWQ89239.1\|66169_66814_+\|RAMP-superfamily-protein	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	7.36094e-106
CP029653.1\|AWQ89521.1\|80730_82152_+\|dihydrolipoyl-dehydrogenase	gnl\|CDD\|235798	PRK06416, PRK06416, dihydrolipoamide dehydrogenase; Reviewed.	0
CP029653.1\|AWQ88722.1\|62242_63148_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.00185e-113
CP029653.1\|AWQ89587.1\|74900_77075_+\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319845	cd07545, P-type_ATPase_Cd-like, P-type heavy metal-transporting ATPase, similar to Staphylococcus aureus plasmid pI258 CadA, a cadmium-efflux ATPase. CadA from gram-positive Staphylococcus aureus plasmid pI258 is required for full Cd(2+) and Zn(2+) resistance. This subfamily also includes CadA, from the gram-negative bacilli, Stenotrophomonas maltophilia D457R, which is a cadmium efflux pump acquired as part of a cluster of antibiotic and heavy metal resistance genes from gram-positive bacteria. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
CP029653.1\|AWQ89263.1\|68757_70026_+\|CRISPR-associated-family-protein	gnl\|CDD\|131720	TIGR02672, hypothetical_protein_SERP2456, CRISPR type III-A/MTUBE-associated protein Csm6. Members of this family as found in CRISPR-associated (cas) gene regions in Streptococcus thermophilus CNRZ1066, Staphylococcus epidermidis RP62A, and Mycobacterium tuberculosis (strains CDC1551 and H37Rv), as part of Mtube-type CRISPR/Cas systems. CRISPR is a widespread form of direct repeat found in archaea and bacteria, with distinctive subtypes each of which has a characteristic sporadic distribution.	1.16357e-132
CP029653.1\|AWQ88866.1\|65742_66168_+\|hypothetical-protein	gnl\|CDD\|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	7.59929e-21
CP029653.1\|AWQ89975.1\|73876_74644_+\|ZIP-Zinc-transporter-family-protein	gnl\|CDD\|223505	COG0428, COG0428, Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism].	4.26029e-19
CP029653.1\|AWQ89596.1\|73221_73623_+\|cadmium-resistance-transcriptional-regulatory-protein-CadC	gnl\|CDD\|236654	PRK10141, PRK10141, DNA-binding transcriptional repressor ArsR; Provisional.	4.54809e-17
CP029653.1\|AWQ89739.1\|78630_80310_-\|transposase-DDE-domain-protein	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.37762e-34
CP029653.1\|AWQ87591.1\|82379_83042_+\|cadmium-resistance-transporter-family-protein	gnl\|CDD\|129861	TIGR00779, quaternary_amine_transporter, cadmium resistance transporter (or sequestration) family protein. These proteins are members of the Cadmium Resistance (CadD) Family (TC 2.A.77). To date, this family of proteins has only been found in Gram-positive bacteria. The CadD family includes several closely related Staphylococcal proteins reported to function in cadmium resistance. Members are predicted to span the membrane five times; the mechanism of resistance is believed to be export but has also been suggested to be binding and sequestration in the membrane. Closely related but outside the scope of this model is another staphylococcal protein that has been reported to possibly function in quaternary ammonium ion export. Still more distant are other members of the broader LysE family (see Vrljic. et al, ). [Transport and binding proteins, Amino acids, peptides and amines].	4.16115e-72

>CP029653.1|AWQ87532.1|70022_70757_+|CRISPR-associated-endoribonuclease-Cas6
MINKITVELDLPDSIRFQYLGSILHGVLMDYLPNDIADQLHHEFAYSPLKQRIYHKNKKVIWEIVCMSDRLFNEIAELFTSKNRLFLKYYQVYIEIYSFNIEKVNVQNIMNQLLETEELNRYVRINIQTPMSFKYQSNYMIFPEVKRFFRSIMIQFDAFFEEYKMYDKETLDFLEKNINIVDYKLKSTRFNLEKVKIPSFTGEIVFKIKGPLPFLQLTHFLLKFGEFSGSGMKTSLGMGKYSII
>CP029653.1|AWQ89263.1|68757_70026_+|CRISPR-associated-family-protein
MKVLFSPIGNSDPWSNDRDGAMLHIVRHYKPDVVVLFFTESIWNGNRNIPGRKNFDWENIVSKVSSRTKVDIKVDSIKYENDFDSYKDIFHFYINEIRTKYSDAEILLNVTSGTPQMESTLCLEYISNPHNMKCIQVSTPAPIEGPKRSFAKLETVTEDLNKVNANEKMASNRSKSINIISFREVMVRSQIKSLVNNYDYEGALNLVSDQKSFRNGKLLRKRLLELTNQIKTHEVFPEINDKYRSVALKKSLFHYLLLNMRYNRLDVAETLIRVKSIAEFILKTYIVGHWPTLIIEKDDKPYLNAEDNLSFIYKYKLLLEKRRQNLDVSRILGLPAFIDILTVLEPNSKLLKEVNAVNDINGLRNSIAHNLETLDLDKNKNYKKIMLSVEAIKNMLHISFPEIEEKDYNYFERKNKEFRELL
>CP029653.1|AWQ88869.1|67735_68758_+|RAMP-superfamily-protein
MTIKNYEVVIKTLGPVHIGSGQVMKKQDYIYDFYNSKVYMINGNKLVKFLKRKNILDTYQNFLRYPPKNPRENGLKDYLDAQNVKQSEWKAFVSYSEKVNQGKKYGNIRPKPLNDLHLMVRDGQNKVYLPGSSIKGAIKTALVSKYNNEKNTDVYSKIKVSDSEPIDERHLAIYQKIDINKSEKPMPLYRECVDVDTEIKFKLTIEDEIYSINEIEQSIQDFYKNYYDKWLVGFKETKGGRRFALEGGMPDVLNQNILFLGAGAGFVSKTTHYQLKSREQAKRDSFDILTKKFRRTYGKMKEMPSNVPVALKGTTNQSLHVSYQQGMCKISFQELNNEVL
>CP029653.1|AWQ88378.1|66899_67733_+|putative-cRISPR-associated-RAMP-protein
MTITSDTLFSALFIEALQLGIETDWLLNDLIISDTFPYENEIYYLPKPLIKIESKEEGNHKAFKKLKYVPVHHYNQYLNGELSAEDATDLNDIFSIGHFSLQTKVSLSAQEIDSSADSEPYSVGTFTFEPEAGLYFIAKGSEETLDQLKDIMTSLQYSGLGGKRNAGYGQFEYEIINNQQLFKLLNQNGEHSILLSTAMAKEDEIKSALKEARYILNKRSGFIQSTNYSEMLVKKSDFYSFSSGSVFKNIFNGDVFNVGHNGKHPVYRYAKPLWLEV
>CP029653.1|AWQ89239.1|66169_66814_+|RAMP-superfamily-protein
MYSKIKISGTIEVVTGLHIGGGGESSMIGAIDSPVVRDLQTKLPIIPGSSIKGKMRSLLAKHFGLKMKQENHNQDDESVLRLFGSSEKGNIQRARLQISDAFFSEKTKEHFAQNDIAYTETKFENTINRLTAVANPRQIERVTRGSEFDFVFIYNVDEESQVENDFENIEKAIHLLENDYLGGGGTRGNGRIQFNDITIETVVGEYDSTNLKIK
>CP029653.1|AWQ88866.1|65742_66168_+|hypothetical-protein
MILAKTKSGKKIDLTFAHEVVKSNVKTVKDKRGKENQVLFNGLTTSKLRNLMEQVNRLYTIAFNSTEDQLNEEFIDELEYLKIKFYYEAGREKSVDEFLKKTLMFPIIDRVIQKESKKFFLDYCKYFEALVAYAKYYQKED
>CP029653.1|AWQ87378.1|63466_65740_+|HD-domain-protein
MDKKTTLMYGSLLHDIGKIIYRSNDHAFARGTHSKLGYNFLSQFSEFKDNEVLDSIAYHHYKELAKANLANDNTAYITYIADNIASGIDRRDVIEEGDEEYEKQAFNFDKYTPLYSVFNIVNSEKLKQISGKFKFSNESNIEYPKTENIQYSSGNYTTLMKDMSYDLEHKLSIKEDTFPSLLQWTESLWQYVPSSTNKNQLIDISLYDHSRITCAIASCIFDYLNENNIHNYKDELFTKYENTKEFYQKEAFLLLSMDMSGIQDFIYNISGSKALKSLRSRSFYLEIMLEVIVDQLLEKLELTRANLLYTGGGHAYLLVSNTDKGKEKINQFNTELKNWFMSEFTTDLSLSIAFEKCSGNDLMNTSGNYRNIWRNVSSKLSDIKAHKYSSEDILKLNHFHSYGDRECKECLRSDIDINDDGLCSICEGIINISNDLRDKSFFVLSETGKLKMPFDKFISVIDYEEAERLAQNNNHIRIYSKNKPYIGVGISTNLWMCDYDYASQNKDMREKGIGSYVEREEGIKRLGVVRADIDNLGATFISGIPEKYNSISRTATLSRQLSLFFKYELNHLLENYQITAIYSGGDDLFLIGAWDDIIEVSVYINEKFKDFTLGKLTMSAGVGMFSGKYPISKMAFETGLLEEAAKTDEKNQIALWVQEKVYNWDEFKKYILEEKLLVLQHGFSQTDEHGKAFIYKMLALLRNNETINIARLAYLLARSKMTEEFTSKIFNWAQNDKDKNQLITALEYYVYQIREVD
>CP029653.1|AWQ88241.1|63147_63453_+|CRISPR-associated-endoribonuclease-Cas2
MYLLVSFDLPRDTKFERRVASKYRTRLLELGFSMKQFSLYERYVSDVQKKDKILEILQQEIPDTGSITLYVLPDEVNNSQITILGKEVKVVVRKEPKLIFL
>CP029653.1|AWQ88722.1|62242_63148_+|CRISPR-associated-endonuclease-Cas1
MKDVIYVENHYFVTVKENSIKFRNVIDKSEKFYLFEEIEAIIFDHYKSYFSHKLVIKCIENDIAIIFCDKKHSPLTQLISSYGMTHRLQRIQSQFQLSGRTRDRIWKKIVVNKIINQSKCLENNLHNENVKLLVNLAKDVSSGDKSNKEAQAARIYFKDLYGKQFKRGRYNDIINSGLNYGYSILRSFIKKELALHGFEMSLGINHRSKENPFNLADDIIEVFRPFVDNIVYEIVFKKNINTFDVNEKKLLLNVLYEKCIIDKKVVRLLDSVKIVIQSLIRCYEENTPTYLLLPKMIEVGN
>CP029653.1|AWQ88703.1|60550_60811_-|hypothetical-protein
MAVELLNRLLKGQVKSLMKTNATVSKRFSEMLRNSINKYNSRSIETSKVIEELIQLAKDIKQEQQRGNELGLNSDEIAFLRCFSFT
>CP029653.1|AWQ88018.1|71866_72025_+|hypothetical-protein
MKFKSKQLVIANQTKVINYRIQVLLKPQANIETQTQVKNNTLPETDEQSNAD
>CP029653.1|AWQ89872.1|72206_72584_+|DDE-domain-protein
MLNERGKLRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSKYLNNFIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEISIMLAS
>CP029653.1|AWQ87615.1|72611_72989_-|signal-peptidase-II
MEIGQTIPLWEGVFHITSLRNKGAAFGILQGQRWFFIIVTLIVVLGIIYYLQTEGRNNRQISFALSLLLGGALGNFFDRLIRGEVIDSLDFRLIDYPIFNLADVFIVSGVALMILEVLLQSKKYS
>CP029653.1|AWQ89596.1|73221_73623_+|cadmium-resistance-transcriptional-regulatory-protein-CadC
MSITSINKKEHDLDGIKSRGKDACETFIFDPEKVERRQQEVGQTDGLSQLFKVFADDTRLKIVYALTQEDEMCVCDVATIIGSTNATASHHLRMLRNMGFAEYRKKGKIVFYRLVSNHVHHLMQEALQLKEKK
>CP029653.1|AWQ89975.1|73876_74644_+|ZIP-Zinc-transporter-family-protein
MFSWTVVSLVLLTSIANLVGGLIVVRKEWSPKALTYLMAFSAGFLLSIGILDLMPEGLENSPENGIYILIGFLVLFSFQRILTTHFHFGYETHEDKLSKKTGGLGAFIGMTIHSFFDGVSIVAGFEVSSELGFLVFVAVLLHKIPDGLTISSIVLVVFNDRKKAFIASAVLALATIFGGALVWLLSDTEFAAEVLGDSFARIALSFSAGVFLYVAATDLLPVVNQSENRKTGLYVLLGVAVFYIASWIIGVVGLE
>CP029653.1|AWQ89587.1|74900_77075_+|cadmium-translocating-P-type-ATPase
MSEATKPLEEKYVYRVDGFSCANCAGKFERNVKKIPGVEDAKVNFGASKISVYGEATIEELEKAGAFENLKVASEKPVRQATQEINQEKEDEKEEKVPFYKKHSTLLYSTLLIVFGYLSVFVNGDENIVTTLLFVASMLIGGLSVFKVGFQNLLRFEFDMKTLMTVAVIGGAIIGEWAEVSVVVILFAISEALERFSMDKARQSIRSIMDIAPKEALVRRKGQEMMVHVDDIAVGDIMIVKPGQKIAMDGMVVSGYSAVNQAAITGESVPVEKAVDDEVFAGTLNEEGLLEVEITKLVEDTTISKIIHLVEEAQGERAPSQAFVEKFAKYYTPIIMIIAALVAVVPPLFFGASWETWVYQGLAVLVVGCPCALVISTPISIVSAIGNAAKKGVLIKGGVYLEEMGALKAIAFDKTGTLTKGVPVVTDFNVLNKQVDENEMLSIITALEYRSQHPLASAIMKRAEEANISYSDVVVDDFSSITGKGIKGTVDGTTYYIGSPKLFKELSNSSFDKNLEKKVATLQNQGKTAMVVGTDKEILAIIAVADEVRESSKEVIQKLHQLGIKNTIMLTGDNKGTANAIGSHVGVKEVQAELMPQDKLDYIKQLKSEYNNVAMIGDGVNDAPALAASTVGIAMGGAGTDTALETADVALMGDDLRKLPFTVKLSRKALNIIKANITFAIAIKFIALLLVIPGWLTLWIAILSDMGATLLVALNSLRLMRVKE
>CP029653.1|AWQ89838.1|77520_78534_+|transposase-IS116/IS110/IS902-family-protein
MERFCCVNQINYIQMNPLEAKFKTSALRSWKTDQADAHKLACLGPTLKQTDNLPIHELIFFELRERVRFHLEIENEQNRLKFQILELLHQTFPGLERLFSSRYSIIALNIAEIFTHPDMVLDIDKEVLITHIFNSTDKGMSMDKATKYALQLRVIAQESYPNVDRHSFLVEKLRLLIQQLKQSIHHLKQLDDAMIQLAQQLDYFENIHSIPGIGKLSTAMIIGEIGDIKRFKSNKQLNAFVGIDIKRYQSGHTHCRDTINKRGNKKARKLLFWVIMNIIRGQHHYDNHVVDYYYKLRKQPNEKPHKTAIIACINRLLKTIHYLVMNHKLYDYQMSPH
>CP029653.1|AWQ89739.1|78630_80310_-|transposase-DDE-domain-protein
MYKDYNMTQLTLPMETSVLIPTNDISRHVNDIVETIPETEFDEFRHHRGATSYHPKMMLKVVLYAYTQSVFSGRKIEKLLNDSIRMMWLSQNQKPSYKTINRFRVNPKVDALLESLFIQFHSQCLKQNLIDDQAIFIDGTKVEANANRYTFVWKKSIQNHESRMNENSKALYHELVINKIIPEIKKDHDNDLTKEEIDLIGSHLDKEIEDLNQHIDNEKCTKIRKQIRLKRTKIKKYKKQINDYSQRKHKYEVQKSILKDRNSYSKTDHDATFMRMKEDHMKNGQLKPGYNLQIATNSQFVLFYNVYQNPTDTRTMIPFLNTIQETYGHLPEYIVADAGYGSEANYMAIIDNFNRTPLITYGMFIKDKTKKYKSDIFNTQNWDYDEINDEFICPNNKRLGFKRYAYRHDKYGFKRDFKLYECDDCSECPLKQQCMNFNSKTNKKIMKNYNWEYFKAQINKKLSEPKTKTIYSQRKIDVEPVFGFMKAILGFTRMSVRGIDKAKRELGFVLMALNIRKVTAQRAENNQKNNKKDNFYIISIEIVFFYLSWDFMSHTLSYD
>CP029653.1|AWQ89521.1|80730_82152_+|dihydrolipoyl-dehydrogenase
MTGEVKKDVDLLVIGAGSGGYVAAIRAAQLGKKVVLVDKAELGGVCLNRGCIPSKALISASERVKHIKHANTMGLKVSGEVQVDMPEVVKWKDGIVNKLTDGIRTLLKGNGVEVISGEAYLTEAHIAKIKIEDEEQIFSYKDLILAIGSLPVELKSMPFDQKRIISSTEALQLQEVPNHLVVVGGGYIGLELGTAYAKFGAKVTILEGSDTILSGTDPILTKTVKRHLKEIGITVITDALVQGGENTGDEVNVHVQVDGKEEIIQCDYCLVSIGRKPNTGKIGLENIGVVLDDQGFIKINNKCQTNIEHVYAIGDCAGGDLLAHKASYEAKIAAEVISGQNNVIDFQAMPFVIFSDPEVAYTGLTEKEAKEKGYETVSSRFPFQANARALSVSDADGFVQVVAEKNTKRVLGVQMVGPEVSSLIAEAVFAIEAGANAEDLSLTIHAHPTLPEPLMEAAEGVMGHATHMLNKKQ
>CP029653.1|AWQ87591.1|82379_83042_+|cadmium-resistance-transporter-family-protein
MNLILTILSALGSFIVTNVDDIFVLMLLFSQARSQAKTGNSGIVSMESKGNRIYPRDIVIGQYLGFALLVLISLLATFGVTLIPDQWVGLLGLIPIYLGVKLFIKGEDEDEGNILSSLNKFNKFYLSVAFITFANGGDNIGIYVPFFSTLNNNQLIITVVTFFIMVAVWCLIGYRLARFRYVSETLEKYGRWIIPIVFIGLGIYIMVENETFRAILSLVN

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Crispr_ID: CP029653_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_3

690151-690243

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029653_3

>merge|CP029653|3|690151-690243|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTACCGCACAACTGCATAAATCCCTCTAATCGCTAAAGGTGAAGAGGAACGCAGTTGGATGCTA

>CP029653|3|3|690151-690243|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA	CCGCACAACTGCATAAATCCCTCTAATCG
CTAAAGGTGAAGAGGAACGCAGTTGGATGCTA

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ89664.1\|684666_685173_+\|ywhD-family-protein	unknown	unknown	gnl\|CDD\|378039
CP029653.1\|AWQ87813.1\|687370_689032_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
CP029653.1\|AWQ88316.1\|679877_680507_+\|tandem-five-TM-family-protein	unknown	unknown	gnl\|CDD\|335700
CP029653.1\|AWQ89622.1\|683328_684624_+\|HD-domain-protein	unknown	unknown	gnl\|CDD\|224004
CP029653.1\|AWQ89338.1\|692423_693143_+\|HAD-hydrolase,-IA,-variant-1-family-protein	unknown	unknown	gnl\|CDD\|223943
CP029653.1\|AWQ90049.1\|699098_699323_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378571
CP029653.1\|AWQ88617.1\|685671_686682_+\|alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|181842
CP029653.1\|AWQ88043.1\|686957_687374_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226896
CP029653.1\|AWQ90130.1\|680959_681898_+\|protein-IolS	unknown	unknown	gnl\|CDD\|381309
CP029653.1\|AWQ87411.1\|691382_692369_+\|fecCD-transport-family-protein	unknown	unknown	gnl\|CDD\|376439
CP029653.1\|AWQ87399.1\|695615_696404_+\|alpha/beta-hydrolase-fold-family-protein	unknown	unknown	gnl\|CDD\|223669
CP029653.1\|AWQ89193.1\|694062_694569_+\|putative-exported-protein	unknown	unknown	unknown
CP029653.1\|AWQ89444.1\|694730_695447_+\|putative-membrane-protein	unknown	unknown	unknown
CP029653.1\|AWQ89220.1\|696653_697028_-\|transcriptional-regulator-SarA	unknown	unknown	gnl\|CDD\|130944
CP029653.1\|AWQ88646.1\|689366_690002_+\|hhH-GPD-superbase-excision-DNA-repair-family-protein	unknown	unknown	gnl\|CDD\|225140
CP029653.1\|AWQ87609.1\|693126_693927_+\|alpha/beta-hydrolase-fold-family-protein	unknown	unknown	gnl\|CDD\|223669
CP029653.1\|AWQ88168.1\|697976_698906_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225778
CP029653.1\|AWQ88610.1\|682812_683289_+\|acetyltransferase-domain-protein	unknown	unknown	gnl\|CDD\|366181
CP029653.1\|AWQ88155.1\|690381_691269_+\|periplasmic-binding-family-protein	unknown	unknown	gnl\|CDD\|238563
CP029653.1\|AWQ89889.1\|682107_682644_+\|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-YwqN	unknown	unknown	gnl\|CDD\|223728

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ89664.1\|684666_685173_+\|ywhD-family-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	1.08203e-97
CP029653.1\|AWQ87813.1\|687370_689032_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
CP029653.1\|AWQ88316.1\|679877_680507_+\|tandem-five-TM-family-protein	gnl\|CDD\|335700	pfam04276, DUF443, Protein of unknown function (DUF443). Family of uncharacterized proteins.	2.66874e-44
CP029653.1\|AWQ89622.1\|683328_684624_+\|HD-domain-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	3.99954e-151
CP029653.1\|AWQ89338.1\|692423_693143_+\|HAD-hydrolase,-IA,-variant-1-family-protein	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	5.71997e-38
CP029653.1\|AWQ90049.1\|699098_699323_-\|hypothetical-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	3.83351e-14
CP029653.1\|AWQ88617.1\|685671_686682_+\|alcohol-dehydrogenase	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
CP029653.1\|AWQ88043.1\|686957_687374_+\|hypothetical-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	6.53088e-59
CP029653.1\|AWQ90130.1\|680959_681898_+\|protein-IolS	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	1.14602e-168
CP029653.1\|AWQ87411.1\|691382_692369_+\|fecCD-transport-family-protein	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	4.4882e-49
CP029653.1\|AWQ87399.1\|695615_696404_+\|alpha/beta-hydrolase-fold-family-protein	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	6.25578e-35
CP029653.1\|AWQ88168.1\|697976_698906_-\|hypothetical-protein	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	9.03596e-35
CP029653.1\|AWQ89220.1\|696653_697028_-\|transcriptional-regulator-SarA	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
CP029653.1\|AWQ88646.1\|689366_690002_+\|hhH-GPD-superbase-excision-DNA-repair-family-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	2.8784e-92
CP029653.1\|AWQ87609.1\|693126_693927_+\|alpha/beta-hydrolase-fold-family-protein	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.88188e-26
CP029653.1\|AWQ88610.1\|682812_683289_+\|acetyltransferase-domain-protein	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
CP029653.1\|AWQ88155.1\|690381_691269_+\|periplasmic-binding-family-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	3.39555e-73
CP029653.1\|AWQ89889.1\|682107_682644_+\|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-YwqN	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26

>CP029653.1|AWQ88646.1|689366_690002_+|hhH-GPD-superbase-excision-DNA-repair-family-protein
MLGTDELYKLLYRHMGPQNWWPADNDIEMMLGAILVQNTRWRNAEIALNQIKEHTHFNPNHILELPIETLQSLIRPSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGELRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYNKLGYENTKSYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNCDFLEPYFKK
>CP029653.1|AWQ87813.1|687370_689032_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVAAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>CP029653.1|AWQ88043.1|686957_687374_+|hypothetical-protein
MDKKVSIHTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>CP029653.1|AWQ88617.1|685671_686682_+|alcohol-dehydrogenase
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>CP029653.1|AWQ89664.1|684666_685173_+|ywhD-family-protein
MSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>CP029653.1|AWQ89622.1|683328_684624_+|HD-domain-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVSPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGKIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>CP029653.1|AWQ88610.1|682812_683289_+|acetyltransferase-domain-protein
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>CP029653.1|AWQ89889.1|682107_682644_+|putative-NAD(P)H-dependent-FMN-containing-oxidoreductase-YwqN
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>CP029653.1|AWQ90130.1|680959_681898_+|protein-IolS
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDDNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVIENIKAADIVLSDDEIQYIDELFPIED
>CP029653.1|AWQ88316.1|679877_680507_+|tandem-five-TM-family-protein
MLCEVIAIYKNPKYRIIKYNDEYLMVNIINNWLVLFIPLLNWLTPKRYIKISQEELENLNTFKPAKNNAFWPALGSSVLFSVTFRKYMPLFNVRLEKTIVIAIFFVVFLGILFFYLNLNRRLALSVFTMNKEKSQKMILLPNLKHFFFIIFAYLYFGGFSFFTLYALITIDVQNIIIFICWGAVTMFFFFINIVPIGIKKAHVILLKKS
>CP029653.1|AWQ88155.1|690381_691269_+|periplasmic-binding-family-protein
MKKSLIAFILIFMLVLSGCGMKDNDKQGSDDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHEKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>CP029653.1|AWQ87411.1|691382_692369_+|fecCD-transport-family-protein
MNVIIDERKENAMTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQIITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>CP029653.1|AWQ89338.1|692423_693143_+|HAD-hydrolase,-IA,-variant-1-family-protein
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKIDNKGENYGSIY
>CP029653.1|AWQ87609.1|693126_693927_+|alpha/beta-hydrolase-fold-family-protein
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELAKSFQVVLIDLRGHGYSDKPRHIEIKDFSEDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLMLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTASFINKHHDEKHV
>CP029653.1|AWQ89193.1|694062_694569_+|putative-exported-protein
MKKLLTASIIACSVVMGVGIANTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>CP029653.1|AWQ89444.1|694730_695447_+|putative-membrane-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMVMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQTFSLIIWILLVVLVIYFTIRLSSRTRL
>CP029653.1|AWQ87399.1|695615_696404_+|alpha/beta-hydrolase-fold-family-protein
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVITYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFLSYYLNFLKSVS
>CP029653.1|AWQ89220.1|696653_697028_-|transcriptional-regulator-SarA
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>CP029653.1|AWQ88168.1|697976_698906_-|hypothetical-protein
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIVLNIFINPDVFSLHFFSNQTFNYTWFVGGLLGVGYLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIIGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSLLASHTHSPAFASLVSFTIGSITLLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTSNIILMPHLGAALTTLIGMFGQILMGILIDHFALFGSPKIAMTSRKTIGLLCILTGIIFLRLF
>CP029653.1|AWQ90049.1|699098_699323_-|hypothetical-protein
MTKTLELSFKSSLDKPVKLQLPQLNNIVTEQVARDSMNALVDLNILKSNSGAITKVHSAQIIDKTTTVLFEAKK

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Crispr_ID: CP029653_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_4

754881-754980

Orphan

Consensus_repeat	Method
AAGAGCCCCTAATTAATAAATTAAAAGGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029653_4

>merge|CP029653|4|754881-754980|CRISPRCasFinder
AAGAGCCCCTAATTAATAAATTAAAAGGGGACTAAAGGAATACAGTTGATTGCTAATGCACCAACAGCAAAAGAGCCCCTAATTAATAAATTAAAAGGGG

>CP029653|4|4|754881-754980|CRISPRCasFinder
AAGAGCCCCTAATTAATAAATTAAAAGGGG	ACTAAAGGAATACAGTTGATTGCTAATGCACCAACAGCAA
AAGAGCCCCTAATTAATAAATTAAAAGGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ88891.1\|756924_758571_+\|transposase-DDE-domain-protein	unknown	unknown	gnl\|CDD\|226192
CP029653.1\|AWQ89396.1\|753079_753724_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225188
CP029653.1\|AWQ87527.1\|753841_754708_+\|lysR-substrate-binding-domain-protein	unknown	unknown	gnl\|CDD\|223656
CP029653.1\|AWQ87776.1\|746208_747006_-\|N-acetylmuramoyl-L-alanine-amidase-sle1	unknown	unknown	gnl\|CDD\|226451
CP029653.1\|AWQ88598.1\|760957_761500_+\|acetyltransferase-domain-protein	unknown	unknown	gnl\|CDD\|379112
CP029653.1\|AWQ87679.1\|761594_762161_-\|putative-lysine-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|224527
CP029653.1\|AWQ88411.1\|756214_756682_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225395
CP029653.1\|AWQ88970.1\|762162_762621_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|178882
CP029653.1\|AWQ89134.1\|750988_751348_+\|putative-transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
CP029653.1\|AWQ87618.1\|744614_745622_+\|phosphate-transporter-family-protein	unknown	unknown	gnl\|CDD\|376541
CP029653.1\|AWQ88538.1\|760578_760878_+\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ89166.1\|748692_750843_+\|bacterial-regulatory-helix-turn-helix,-AraC-family-protein	unknown	unknown	gnl\|CDD\|197666
CP029653.1\|AWQ89487.1\|759667_759985_+\|acetyltransferase-family-protein	unknown	unknown	gnl\|CDD\|366181
CP029653.1\|AWQ90115.1\|752253_752727_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226072
CP029653.1\|AWQ89332.1\|760051_760441_+\|putative-lipoprotein	unknown	unknown	unknown
CP029653.1\|AWQ88294.1\|752815_752935_+\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ87708.1\|751537_752254_+\|DNA-binding-regulatory,-YebC/PmpR-family-protein	unknown	unknown	gnl\|CDD\|237084
CP029653.1\|AWQ88078.1\|747366_748011_+\|inhibitor-of-apoptosis-promoting-Bax1-family-protein	unknown	unknown	gnl\|CDD\|223742
CP029653.1\|AWQ89052.1\|758725_759415_-\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ88248.1\|755003_756218_+\|major-Facilitator-Superfamily-protein	unknown	unknown	gnl\|CDD\|341024

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ88891.1\|756924_758571_+\|transposase-DDE-domain-protein	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	4.60304e-37
CP029653.1\|AWQ89396.1\|753079_753724_+\|hypothetical-protein	gnl\|CDD\|225188	COG2306, COG2306, Predicted RNA-binding protein, associated with RNAses E/G family [General function prediction only].	6.78593e-91
CP029653.1\|AWQ87527.1\|753841_754708_+\|lysR-substrate-binding-domain-protein	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	6.18267e-39
CP029653.1\|AWQ87776.1\|746208_747006_-\|N-acetylmuramoyl-L-alanine-amidase-sle1	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.45836e-40
CP029653.1\|AWQ88598.1\|760957_761500_+\|acetyltransferase-domain-protein	gnl\|CDD\|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	6.895e-28
CP029653.1\|AWQ87679.1\|761594_762161_-\|putative-lysine-decarboxylase-family-protein	gnl\|CDD\|224527	COG1611, COG1611, Predicted Rossmann fold nucleotide-binding protein [General function prediction only].	1.24037e-61
CP029653.1\|AWQ88411.1\|756214_756682_+\|hypothetical-protein	gnl\|CDD\|225395	COG2839, COG2839, Uncharacterized protein conserved in bacteria [Function unknown].	8.41098e-45
CP029653.1\|AWQ88970.1\|762162_762621_-\|hypothetical-protein	gnl\|CDD\|178882	PRK00124, PRK00124, YaiI/YqxD family protein.	4.39168e-77
CP029653.1\|AWQ89134.1\|750988_751348_+\|putative-transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	8.17439e-23
CP029653.1\|AWQ87618.1\|744614_745622_+\|phosphate-transporter-family-protein	gnl\|CDD\|376541	pfam01384, PHO4, Phosphate transporter family. This family includes PHO-4 from Neurospora crassa which is a is a Na(+)-phosphate symporter. This family also contains the leukaemia virus receptor.	5.23541e-104
CP029653.1\|AWQ89166.1\|748692_750843_+\|bacterial-regulatory-helix-turn-helix,-AraC-family-protein	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	2.37726e-19
CP029653.1\|AWQ89487.1\|759667_759985_+\|acetyltransferase-family-protein	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	6.48028e-13
CP029653.1\|AWQ90115.1\|752253_752727_+\|hypothetical-protein	gnl\|CDD\|226072	COG3542, COG3542, Uncharacterized conserved protein [Function unknown].	1.29027e-72
CP029653.1\|AWQ87708.1\|751537_752254_+\|DNA-binding-regulatory,-YebC/PmpR-family-protein	gnl\|CDD\|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	8.8628e-136
CP029653.1\|AWQ88078.1\|747366_748011_+\|inhibitor-of-apoptosis-promoting-Bax1-family-protein	gnl\|CDD\|223742	COG0670, COG0670, Integral membrane protein, interacts with FtsH [General function prediction only].	2.53359e-32
CP029653.1\|AWQ88248.1\|755003_756218_+\|major-Facilitator-Superfamily-protein	gnl\|CDD\|341024	cd17471, MFS_Set, Sugar efflux transporter (Set) family of the Major Facilitator Superfamily of transporters. This family is composed of sugar transporters such as Escherichia coli Sugar efflux transporter SetA, SetB, SetC and other sugar transporters. SetA, SetB, and SetC are involved in the efflux of sugars such as lactose, glucose, IPTG, and substituted glucosides or galactosides. They may be involved in the detoxification of non-metabolizable sugar analogs. The Set family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.11563e-101

>CP029653.1|AWQ87527.1|753841_754708_+|lysR-substrate-binding-domain-protein
MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFGVDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIGQTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFNDDHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKEMLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFVNLMTSFVEEPKA
>CP029653.1|AWQ89396.1|753079_753724_+|hypothetical-protein
MKVKYIDKRHWRRLIDREYTEVKVNNNRFKGIIGLVTMKKVRDPLEVTVVGQNIIVADDNYKWLQILPEKKRYSITVMFDNKGNPLEYYFDINIKNITQKGNARTVDLCLDVLALPSGEYELVDEDDLMFALESEQITKKQFHEAYMIAHQIMAELENDFKGFQKKIMYCFNKINAKAQKIHQKPQNKTNFEKSKQIKPKQYNQTKNHQQQKKN
>CP029653.1|AWQ88294.1|752815_752935_+|hypothetical-protein
MVLQLILMKIALNDFEKDKSVLFIFLKNHFYEEMCVLSN
>CP029653.1|AWQ90115.1|752253_752727_+|hypothetical-protein
MKSAEQWIDELQLESHPEGGFYRETIREVLKDGRRAPFSSIYFLLTDDNISHFHRIDADEVWYYHAGDSLTIHMINPDGEYTTATLGTDIQNGDVLQYAVLKGTIFASSIEISNTYSLVGCMCQPAFEFKQFELFKQSELITQYPHLKSVIEKYALK
>CP029653.1|AWQ87708.1|751537_752254_+|DNA-binding-regulatory,-YebC/PmpR-family-protein
MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESNQALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNNVNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDEILETLMEQDVDVNDVIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKLIDALEDLEDVQNVFHNVDLK
>CP029653.1|AWQ89134.1|750988_751348_+|putative-transcriptional-regulator
MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKHCKDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERLSKVRSSKDERKIYIYLNDDDISKFNALFEDVEQFLNI
>CP029653.1|AWQ89166.1|748692_750843_+|bacterial-regulatory-helix-turn-helix,-AraC-family-protein
MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKIIEDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLLLKLTYRYLDNQPLNDADVRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYIYQNVNQRLTLKSAADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDSTISNISEHLGFSSSSTYSKMFKSYMDITPNEYRNLSKFNKSIMLNPEPLVGGMAQEVKEVILNYIDHYKNHLTDVIHIDEDKFEIPKLFQTVIQINTYTEMKLVFLEGLFKTLLNKNSQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESNLKIAFNINDIETTYYVEEAFMNVIRQLSPNEINHHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFDKPSVFKSLVSQIKRLKFDSLIIDNANLSSPYLMGESDELLLKNILHFKNLKQVINELDIEQEKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFHGFGLNIFDNHQTFNAMHLYDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYYCLVIYDWRVIESETIMSNFEDSQVYINFKNNILNDKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNYLKPAIEIKEHNFSNNSLNINVTFNALYIIKIGKK
>CP029653.1|AWQ88078.1|747366_748011_+|inhibitor-of-apoptosis-promoting-Bax1-family-protein
MSQNTNHSYYHQNQHAQAISKVWLYFMYYWIIFGIGCYLGQFLPLSWRQPLSFGLLIIILATLVFERARRFGLIISHIYAVVIGLLSYATFTTYLQNLGPDIFYKNIALAIFAFIAFGIIGYFFVGDASSIGKYLFVTLITLIIASLIGIFLQNPIFYTIITVVSLLLFLLYTLYDFNRLKRGDYSPREMGFNLFINLLNIIKDILYLANMFRR
>CP029653.1|AWQ87776.1|746208_747006_-|N-acetylmuramoyl-L-alanine-amidase-sle1
MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKYNTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNTSNTSPQAGSASSHTVQAGESLNIIANRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNLYTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGPYGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH
>CP029653.1|AWQ87618.1|744614_745622_+|phosphate-transporter-family-protein
MSYIIIVTIAVVIFSLIFDFINGFHDTANAVATAVSTRALTPKTAILMAAVMNFIGALTFTGVAGTITKDIVDPFKLENGLVVVLAAILAAIIWNLATWFYGIPSSSSHALIGSIAGAAIASEGSFGVLHYQGFTKIIIVLIVSPIIAFCVGFLMYSIFKVIFKNANLTRANRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVANVQNDGSVEPQLWVKFACATAMGLGTAIGGWKIIKTVGGNIMKIRPANGAAADLSSALTIFVASSLHFPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMIITWVITLPISALLAGLLFYILNLFF
>CP029653.1|AWQ88248.1|755003_756218_+|major-Facilitator-Superfamily-protein
MFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLQTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKEDVIST
>CP029653.1|AWQ88411.1|756214_756682_+|hypothetical-protein
MTIVLWLLIIAAFMLAFVGLIKPIIPSVLVLWVGFLIYQFGFHNQHLSWVFYVSMALLTILILCADFLANKYFVNRFGGSKFGEYAALIGVVIGCFVLPPFGIIIIPFILVFIVELIQGYSFERAVKVSIGSIVAFLTSSIAQASLGHKSLKKQQ
>CP029653.1|AWQ88891.1|756924_758571_+|transposase-DDE-domain-protein
MYKNYNMTQLTLPIETSVRIPQNDISRYVNEIVETIPDSEFDEFRHHRGATSYHPKMMLKIILYAYTQSVFSGRRIEKLLHDSIRMMWLAQNQTPSYKTINRFRVNPNTDALIESLFIQFHSQCLKQNLIDDSSIFIDGTKVEANANRYTFVWKKSIRNHESKLNENSKALYRDLVEEKIIPEIKEDGDSDLTIEEIDLIGSHLDKEIEDLNHSIQNEDCTQIRKQTRKKRTEIKKFKKKFDDYSERKSKYEEQKSILKDRNSFSKTDHDATFMRMKEDHMKNGQLKPGYNLQIATNSQFVLSYDLFQNPTDTRTLIPFLTMIQNTFGYLPEYIVADAGYGSEQNYMAIIDDFNKTPLITYGMFIKDKTRKFKSDIFNTQNWKYDELNDEFICPNNKRIGFKRYAYRNNRYGFKRDFKLYECDDCSACSLRQQCMKPNSKSNKKIMKNYNWEYFKAQINQKLSEPETKKIYSQRKIDVEPVFGFMKAILGFTRMSVRGINKVKRELGFVLMALNIRKIVARRAVYYQIHLKKADFYQIINRNQLFYIA
>CP029653.1|AWQ89052.1|758725_759415_-|hypothetical-protein
MKSTAQLTKENNVKSLRLSNTDREIFENYMTYMRSDFRVNPHDTELIINRILKQLLSAEQHGLLALDFFNHDPKAHAIKELKAMPNETFKNIFKYIYQHIVLLIGIVSFLKGFLGFFMEKSGSNLYFVSFPFSVVVGFFIVFLFIWFSFKTIQLQCFNNSNWIWIFTYLAIILLIVGFFYVFFIPQSLLAFGPYIQVSNWVFIIFSFIVMPIGLRIERNISKKHSHTFL
>CP029653.1|AWQ89487.1|759667_759985_+|acetyltransferase-family-protein
MICSRLEHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNIELLYVEPQFRKLGIATQLKIALEKWAKTMNAKRISSTIHKSNLPMISLNKDLGYQVSHVKMYKDID
>CP029653.1|AWQ89332.1|760051_760441_+|putative-lipoprotein
MKKLIISIMAIMLFLTGCGKSQEKATLEKDIDNLQKENKELKDKKEKLQQEKEKLADKQKDLEKEVKDLKPSKEDNKDDKKDEDKNKDKDKEASQDKQSKDQTKSSDKDNHKKPTSTDKDQKANDKHQS
>CP029653.1|AWQ88538.1|760578_760878_+|hypothetical-protein
MHEQDFRILEGQDITLPELGRELENITGRTIADSTGEIKRVIAHLPNFESDTDTFVATYRLNHQQDFIDATFTALKSDRARLKEVPVHVELISYISKSK
>CP029653.1|AWQ88598.1|760957_761500_+|acetyltransferase-domain-protein
MIYCETERLILRDWHEDDLLPFQKMNANYDVRKYFPSLLSYRRSELDMRTMDAVIKDYGIGLFAVEDKESHQWIGFIGLNYIPETSDYPFKELPLYEIGWRLLPEFWGKGLATEGAKATLKLAEQHQIYDVYSFTAEANKASQRVMEKIGMTVYDHFELPNLSKYHLLKRQVRYYINLRK
>CP029653.1|AWQ87679.1|761594_762161_-|putative-lysine-decarboxylase-family-protein
MKRIAVYCGASKGHDPSYVQKAYDLGKYFAEQGYELVFGAGSIGIMGAIQDGVLDHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFVMAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYRALAPLCDTKESLIESILNFKPLGTRSYD
>CP029653.1|AWQ88970.1|762162_762621_-|hypothetical-protein
MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPPHVSTLYVDDGPDAVDYKIVQLSTKDDIVITQDYGLASLLVDKVLIVMHHNGKIYNSKNIQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEKSLLRVIHRIKELD

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Click the colored protein region to show detailed information

Crispr_ID: CP029653_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_5

844526-844610

Unclear

Consensus_repeat	Method
CACCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of CP029653_5

>merge|CP029653|5|844526-844610|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTTTGTTGGGGCCCACACCCCAACTTGCATTGCCTGTAGAA

>CP029653|5|5|844526-844610|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTTTGTTGGGGCCCA
CACCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ89452.1\|856520_857456_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
CP029653.1\|AWQ88150.1\|843357_844350_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
CP029653.1\|AWQ87501.1\|832451_833507_+\|glycosyl-transferase-4-family-protein	unknown	unknown	gnl\|CDD\|133463
CP029653.1\|AWQ88487.1\|852733_853666_+\|HPr(Ser)-kinase/phosphatase	unknown	unknown	gnl\|CDD\|235459
CP029653.1\|AWQ89476.1\|849276_852123_+\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP029653.1\|AWQ89209.1\|833670_834312_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224653
CP029653.1\|AWQ89200.1\|835685_836768_+\|type-III-restriction-enzyme,-res-subunit	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|226583
CP029653.1\|AWQ89031.1\|846778_847015_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227234
CP029653.1\|AWQ89439.1\|845118_845958_+\|staphyloxanthin-biosynthesis-protein,-putative	unknown	unknown	gnl\|CDD\|226451
CP029653.1\|AWQ90023.1\|836760_837435_+\|putative-amidophosphoribosyltransferase,-ComFC	unknown	unknown	gnl\|CDD\|223970
CP029653.1\|AWQ89504.1\|838075_839746_-\|transposase-DDE-domain-protein	unknown	unknown	gnl\|CDD\|226192
CP029653.1\|AWQ89331.1\|853671_854514_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP029653.1\|AWQ88215.1\|831063_832134_-\|diguanylate-cyclase-domain-protein	unknown	unknown	gnl\|CDD\|143635
CP029653.1\|AWQ88741.1\|847283_849269_+\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP029653.1\|AWQ87517.1\|834455_835322_+\|EDD,-DegV-family-domain-protein	unknown	unknown	gnl\|CDD\|273257
CP029653.1\|AWQ87630.1\|840393_842925_+\|preprotein-translocase,-SecA-subunit	unknown	unknown	gnl\|CDD\|237259
CP029653.1\|AWQ88141.1\|854521_855007_+\|bacterial-transferase-hexapeptide-family-protein	unknown	unknown	gnl\|CDD\|100053
CP029653.1\|AWQ89072.1\|837495_838068_+\|ribosomal-subunit-interface-protein	unknown	unknown	gnl\|CDD\|224461
CP029653.1\|AWQ89964.1\|855014_856454_+\|TPR-repeat-family-protein	unknown	unknown	gnl\|CDD\|276808
CP029653.1\|AWQ89403.1\|846131_846782_+\|HD-containing-hydrolase-like-enzyme-family-protein	unknown	unknown	gnl\|CDD\|378993

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ89452.1\|856520_857456_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
CP029653.1\|AWQ88150.1\|843357_844350_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
CP029653.1\|AWQ87501.1\|832451_833507_+\|glycosyl-transferase-4-family-protein	gnl\|CDD\|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	2.69988e-87
CP029653.1\|AWQ88487.1\|852733_853666_+\|HPr(Ser)-kinase/phosphatase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP029653.1\|AWQ89476.1\|849276_852123_+\|excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP029653.1\|AWQ89209.1\|833670_834312_-\|hypothetical-protein	gnl\|CDD\|224653	COG1739, COG1739, Uncharacterized conserved protein [Function unknown].	7.46066e-72
CP029653.1\|AWQ89200.1\|835685_836768_+\|type-III-restriction-enzyme,-res-subunit	gnl\|CDD\|226583	COG4098, comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair].	1.30855e-179
CP029653.1\|AWQ89031.1\|846778_847015_+\|hypothetical-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
CP029653.1\|AWQ89439.1\|845118_845958_+\|staphyloxanthin-biosynthesis-protein,-putative	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	3.29354e-42
CP029653.1\|AWQ90023.1\|836760_837435_+\|putative-amidophosphoribosyltransferase,-ComFC	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	1.20522e-50
CP029653.1\|AWQ89504.1\|838075_839746_-\|transposase-DDE-domain-protein	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.46139e-34
CP029653.1\|AWQ89331.1\|853671_854514_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	6.12313e-120
CP029653.1\|AWQ88215.1\|831063_832134_-\|diguanylate-cyclase-domain-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	1.36992e-45
CP029653.1\|AWQ88741.1\|847283_849269_+\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP029653.1\|AWQ87517.1\|834455_835322_+\|EDD,-DegV-family-domain-protein	gnl\|CDD\|273257	TIGR00762, DegV, EDD domain protein, DegV family. This family of proteins is related to DegV of Bacillus subtilis and includes paralogous sets in several species (B. subtilis, Deinococcus radiodurans, Mycoplasma pneumoniae) that are closer in percent identity to each than to most homologs from other species. This suggests both recent paralogy and diversity of function. DegV itself is encoded immediately downstream of DegU, a transcriptional regulator of degradation, but is itself uncharacterized. Crystallography suggested a lipid-binding site, while comparison of the crystal structure to dihydroxyacetone kinase and to a mannose transporter EIIA domain suggests a conserved domain, EDD, with phosphotransferase activity. [Unknown function, General].	9.17692e-120
CP029653.1\|AWQ87630.1\|840393_842925_+\|preprotein-translocase,-SecA-subunit	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
CP029653.1\|AWQ88141.1\|854521_855007_+\|bacterial-transferase-hexapeptide-family-protein	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	7.57447e-30
CP029653.1\|AWQ89072.1\|837495_838068_+\|ribosomal-subunit-interface-protein	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
CP029653.1\|AWQ89964.1\|855014_856454_+\|TPR-repeat-family-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	7.77476e-06
CP029653.1\|AWQ89403.1\|846131_846782_+\|HD-containing-hydrolase-like-enzyme-family-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58

>CP029653.1|AWQ88150.1|843357_844350_+|peptide-chain-release-factor-2
MAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDGEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>CP029653.1|AWQ87630.1|840393_842925_+|preprotein-translocase,-SecA-subunit
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKSVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMIVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>CP029653.1|AWQ89504.1|838075_839746_-|transposase-DDE-domain-protein
MYKDYNMTQLTLPMETSVLIPTNDISRHVNDIVETIPETEFDEFRHHRGATSYHPKMMLKVVLYAYTQSVFSGRKIEKLLNDSIRMMWLSQNQKPSYKTINRFRVNPKVDALLESLFIQFHSQCLKQNLIDDQAIFIDGTKVEANANRYTFVWKKSIQNHESRMNENSKALYHELVINKIIPEIKKDHDNDLTKEEIDLIGSHLDKEIEDLNQHIDNEKCTKIRKQIRLKRTKIKKYKKQINDYSQRKHKYEVQKSILKDRNSYSKTDHDATFMRMKEDHMKNGQLKPGYNLQIATNSQFVLFYNVYQNPTDTRTMIPFLNTIQETYGHLPEYIVADAGYGSEANYMAIIDNFNRTPLITYGMFIKDKTKKYKSDIFNTQNWDYDEINDEFICPNNKRLGFKRYAYRHDKYGFKRDFKLYECDDCSECPLKQQCMNFNSKTNKKIMKNYNWEYFKAQINKKLSEPKTKTIYSQRKIDVEPVFGFMKAILGFTRMSVRGIDKAKRELGFVLMALNIRKVTAQRAENNQKNNKKDNFYIISIEIVFFYLSWDFMSHTL
>CP029653.1|AWQ89072.1|837495_838068_+|ribosomal-subunit-interface-protein
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>CP029653.1|AWQ90023.1|836760_837435_+|putative-amidophosphoribosyltransferase,-ComFC
MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKARRCSRCLKYLDQNEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFSKDYYLCELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPKQSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFKVFAFAR
>CP029653.1|AWQ89200.1|835685_836768_+|type-III-restriction-enzyme,-res-subunit
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRMRQTILLYAVTGAGKTEMMFQGIQYARRQGDNIAIVSPRVDVVVEISKRIKDAFLNEDIDILHQQSSQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKSLQQALKSSSKVEHATIYMTATPPKQLLSEIPLENIIKLPARFHKKSLPVPKYRYFKLNNNKIQKMLYRILQDQINNQRYTLVFFNNIETMIKTFSIYKQKITKLTYVHSEDVFRFEKVEQLRNGQYDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLECPTGKVLFFHEGVSMNMIQAKKEIQKMNKLALKRGWIDE
>CP029653.1|AWQ87517.1|834455_835322_+|EDD,-DegV-family-domain-protein
MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEIAIEEFYNKMASSQTIPTTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSYQAGEMVEGVNVHAFDSKLAAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYLIVDDLKNLQKSGRITGAQAWVGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKVLDIVKDFEEVTLFVINGDHFEDGQALYKKLQDDCPSAYQVAYSEFGPVVAAHLGSGGLGLGYVGRKIRLT
>CP029653.1|AWQ89209.1|833670_834312_-|hypothetical-protein
MTQNIITVKKEHIIENVISKSRFIAHIKPVQNEDEAKAFIAAIKKEHKDATHNCSAYTIGPEMNIQKANDDGEPTGTAGVPMLDILKKLDVHNACVVVTRYFGGIKLGGGGLIRAYSGAVRDVIYDIGRVELREAVPCIVTLNYDQTGKFEYELASTHFMLRNQTYTDKVSYYIDVVKSDYEAFINFLNQMTAGNFDLTEETPKQLPFDIPTE
>CP029653.1|AWQ87501.1|832451_833507_+|glycosyl-transferase-4-family-protein
MVTLLLVAVTMIVSLTITPIVIAISKRLNLVDKPNFRKVHTKPISVMGGTVILFSFLIGIWIGHPIETEIKPLIIGAIIMYVLGLVDDIYDLKPYIKLAGQIAAALVVAFYGVTIDFISLPMGTTIHFGFLSIPITVIWIVAITNAINLIDGLDGLASGVSAIGLITIGFIAILQANIFITMICCVLLGSLIGFLFYNFHPAKIFLGDSGALMIGFIIGFLSLLGFKNITIIALFFPIVILAVPFIDTLFAMIRRVKKGQHIMQADKSHLHHKLLALGYTHRQTVLLIYSISILFSLSSIILYVSPPLGVVLMFVLIIFSIELIVEFTGLIDNNYRPILNLISRKSSHKEE
>CP029653.1|AWQ88215.1|831063_832134_-|diguanylate-cyclase-domain-protein
MFEAFIYNISVIVAGIYLFHRLQYSENKRMVFSKAYVTVLMTIVSLLLSVYPIPYREDYLIHLTFVPLLFLGRFTNMVYTLSATVIVAIVEIVVFNNSIMYGVTLIVIAAATSAIGPFLKQNDVLSLLILNVVTIIILFGVALVSPIYTLSEVIILIPISLIITLASAITFVDIWHFFSLVNRYENEDKYDYLTGLGNVKEFDRHLNEISRKAEKEHQSIALLLIDIDGFKDVNDTYSHKSGDAVLKQMSQLLKNYVPNQFKIFRNGGEEFSVVIHNYSLDQSVKLAENIRSGVEKSSFHLPNKEVIKLSVSIGVGYLTDDDPKSQRKVFKDADDMVHVAKNQGRNKVMFNPIINL
>CP029653.1|AWQ89439.1|845118_845958_+|staphyloxanthin-biosynthesis-protein,-putative
MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKTVKSPVRKASQAKKVVQQPVQQASKKVVVKQAPKQTVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP029653.1|AWQ89403.1|846131_846782_+|HD-containing-hydrolase-like-enzyme-family-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP029653.1|AWQ89031.1|846778_847015_+|hypothetical-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP029653.1|AWQ88741.1|847283_849269_+|excinuclease-ABC-subunit-B
MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP029653.1|AWQ89476.1|849276_852123_+|excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNINLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP029653.1|AWQ88487.1|852733_853666_+|HPr(Ser)-kinase/phosphatase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP029653.1|AWQ89331.1|853671_854514_+|prolipoprotein-diacylglyceryl-transferase
MGGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPGEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTRKVK
>CP029653.1|AWQ88141.1|854521_855007_+|bacterial-transferase-hexapeptide-family-protein
MRKFLSKEYHRTNPLWHVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQILNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP029653.1|AWQ89964.1|855014_856454_+|TPR-repeat-family-protein
MAQKNNNVIPMTFDDAFYRKMANQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLKEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYHNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP029653.1|AWQ89452.1|856520_857456_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA

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Crispr_ID: CP029653_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_6

974636-974721

Orphan

Consensus_repeat	Method
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029653_6

>merge|CP029653|6|974636-974721|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAAGCTGGTGGAAAGCCAGCTTACAATAATGTGCAAGTTGG

>CP029653|6|6|974636-974721|CRISPRCasFinder
AAAGTCAGCTTACAATAATGTGCAAGTTGG	CGGGGCCCCAACACAGAAGCTGGTGG
AAAGCCAGCTTACAATAATGTGCAAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ87750.1\|985964_989618_+\|helicase-exonuclease-AddAB,-AddA-subunit	unknown	unknown	gnl\|CDD\|274299
CP029653.1\|AWQ88008.1\|982487_985964_+\|helicase-exonuclease-AddAB,-AddB-subunit	unknown	unknown	gnl\|CDD\|213736
CP029653.1\|AWQ90046.1\|970506_971634_+\|flavin-oxidoreductase-/-NADH-oxidase-family-protein	unknown	unknown	gnl\|CDD\|240086
CP029653.1\|AWQ89196.1\|968759_969353_+\|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase/CLD-family-protein	unknown	unknown	gnl\|CDD\|238908
CP029653.1\|AWQ88909.1\|965355_965784_-\|na(+)/H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
CP029653.1\|AWQ87986.1\|974879_975809_-\|glycerophosphoryl-diester-phosphodiesterase-family-protein	unknown	unknown	gnl\|CDD\|176543
CP029653.1\|AWQ87619.1\|980632_981208_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223475
CP029653.1\|AWQ90127.1\|981212_981737_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP029653.1\|AWQ88309.1\|989783_990686_+\|fumarylacetoacetate-(FAA)-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
CP029653.1\|AWQ88737.1\|981752_982328_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP029653.1\|AWQ89482.1\|976050_977430_-\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
CP029653.1\|AWQ88426.1\|973240_974485_+\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
CP029653.1\|AWQ89618.1\|977419_978625_-\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
CP029653.1\|AWQ89840.1\|965776_968182_-\|na(+)/H(+)-antiporter-subunit-A1	unknown	unknown	gnl\|CDD\|237155
CP029653.1\|AWQ87704.1\|963525_965022_-\|na(+)/H(+)-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
CP029653.1\|AWQ88634.1\|968312_968696_-\|kinase-associated-B-family-protein	unknown	unknown	gnl\|CDD\|378054
CP029653.1\|AWQ90035.1\|965014_965269_-\|na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
CP029653.1\|AWQ89383.1\|978975_980307_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP029653.1\|AWQ88854.1\|971941_973132_+\|ornithine--oxo-acid-transaminase	unknown	unknown	gnl\|CDD\|179736
CP029653.1\|AWQ88157.1\|969767_970145_+\|S1-RNA-binding-domain-protein	unknown	unknown	gnl\|CDD\|224023

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ87750.1\|985964_989618_+\|helicase-exonuclease-AddAB,-AddA-subunit	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP029653.1\|AWQ88008.1\|982487_985964_+\|helicase-exonuclease-AddAB,-AddB-subunit	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0
CP029653.1\|AWQ90046.1\|970506_971634_+\|flavin-oxidoreductase-/-NADH-oxidase-family-protein	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
CP029653.1\|AWQ89196.1\|968759_969353_+\|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase/CLD-family-protein	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
CP029653.1\|AWQ88909.1\|965355_965784_-\|na(+)/H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
CP029653.1\|AWQ87986.1\|974879_975809_-\|glycerophosphoryl-diester-phosphodiesterase-family-protein	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	8.83368e-151
CP029653.1\|AWQ87619.1\|980632_981208_+\|hypothetical-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	4.0006e-40
CP029653.1\|AWQ90127.1\|981212_981737_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.75286e-49
CP029653.1\|AWQ88309.1\|989783_990686_+\|fumarylacetoacetate-(FAA)-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.74159e-87
CP029653.1\|AWQ88737.1\|981752_982328_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	1.63465e-53
CP029653.1\|AWQ89482.1\|976050_977430_-\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
CP029653.1\|AWQ88426.1\|973240_974485_+\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
CP029653.1\|AWQ89618.1\|977419_978625_-\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
CP029653.1\|AWQ89840.1\|965776_968182_-\|na(+)/H(+)-antiporter-subunit-A1	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
CP029653.1\|AWQ87704.1\|963525_965022_-\|na(+)/H(+)-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
CP029653.1\|AWQ88634.1\|968312_968696_-\|kinase-associated-B-family-protein	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
CP029653.1\|AWQ90035.1\|965014_965269_-\|na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	7.96732e-49
CP029653.1\|AWQ89383.1\|978975_980307_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP029653.1\|AWQ88854.1\|971941_973132_+\|ornithine--oxo-acid-transaminase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
CP029653.1\|AWQ88157.1\|969767_970145_+\|S1-RNA-binding-domain-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44

>CP029653.1|AWQ88426.1|973240_974485_+|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>CP029653.1|AWQ88854.1|971941_973132_+|ornithine--oxo-acid-transaminase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINKNTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>CP029653.1|AWQ90046.1|970506_971634_+|flavin-oxidoreductase-/-NADH-oxidase-family-protein
MKSKYEPLFDKVVLPNGVELRNRFVLAPLTHISSNDDGTISDIELPYIEKRSQDVGITSNAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPDGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWANQYKFPIAVIEEVLKAKEVYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATAREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADDALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>CP029653.1|AWQ88157.1|969767_970145_+|S1-RNA-binding-domain-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>CP029653.1|AWQ89196.1|968759_969353_+|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase/CLD-family-protein
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>CP029653.1|AWQ88634.1|968312_968696_-|kinase-associated-B-family-protein
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>CP029653.1|AWQ89840.1|965776_968182_-|na(+)/H(+)-antiporter-subunit-A1
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWIWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASKANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTVFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKCSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>CP029653.1|AWQ88909.1|965355_965784_-|na(+)/H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>CP029653.1|AWQ90035.1|965014_965269_-|na(+)/H(+)-antiporter-subunit-C
MGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>CP029653.1|AWQ87704.1|963525_965022_-|na(+)/H(+)-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPLRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK
>CP029653.1|AWQ87986.1|974879_975809_-|glycerophosphoryl-diester-phosphodiesterase-family-protein
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNHIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDENVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNKNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>CP029653.1|AWQ89482.1|976050_977430_-|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLSTYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>CP029653.1|AWQ89618.1|977419_978625_-|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMRAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>CP029653.1|AWQ89383.1|978975_980307_+|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGGAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>CP029653.1|AWQ87619.1|980632_981208_+|hypothetical-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVDTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLIVFWIVGKKLEQHFMGSKKE
>CP029653.1|AWQ90127.1|981212_981737_+|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKKLDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>CP029653.1|AWQ88737.1|981752_982328_+|signal-peptidase-I
MKKELLEWIISIAVAFVILFIVGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKYNFNPENTKN
>CP029653.1|AWQ88008.1|982487_985964_+|helicase-exonuclease-AddAB,-AddB-subunit
MTLHAYLGRAGTGKSTKMLTEIKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLESFIADKNMQTRTKNKLEDIALIYREFEQRIQNEFITGEDALQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEISNELNISIERQYFNQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQINPMLRLLKTDVLTTSYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAATVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGNVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLSQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP029653.1|AWQ87750.1|985964_989618_+|helicase-exonuclease-AddAB,-AddA-subunit
MTIPEKPQGVIWTDAQWQSIYETGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDISYLTGHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFHEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTLDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVRYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVFDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQIEDSSRPNVNISIIYFEDVSTETILDNDEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADTKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP029653.1|AWQ88309.1|989783_990686_+|fumarylacetoacetate-(FAA)-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVERLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK

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Crispr_ID: CP029653_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_7

2083245-2083372

Orphan

Consensus_repeat	Method
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029653_7

>merge|CP029653|7|2083245-2083372|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTCATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTAAATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

>CP029653|7|7|2083245-2083372|CRISPRCasFinder
AATTATGGAGCGGAAGATAGGATTTACACCTATACCTC	ATTCCAGGAAGGAATGTATTCTAAGAGTTGAAATACTCCCGCATTATTATTA
AATTATGGAGCGGAAGATAGGATTTGCACCTATACCTC

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ88872.1\|2073823_2075209_-\|fumarate-hydratase,-class-II	unknown	unknown	gnl\|CDD\|234779
CP029653.1\|AWQ89582.1\|2095011_2096106_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226614
CP029653.1\|AWQ87832.1\|2098322_2098865_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184219
CP029653.1\|AWQ88820.1\|2077810_2078938_-\|epoxyqueuosine-reductase	unknown	unknown	gnl\|CDD\|272993
CP029653.1\|AWQ87508.1\|2096296_2097943_-\|putative-multidrug-export-ATP-binding/permease-protein	unknown	unknown	gnl\|CDD\|224055
CP029653.1\|AWQ88362.1\|2081519_2082581_-\|phosphotransferase-system,-EIIC-family-protein	unknown	unknown	gnl\|CDD\|226167
CP029653.1\|AWQ87522.1\|2077335_2077806_-\|tRNA-(cytidine(34)-2'-O)-methyltransferase	unknown	unknown	gnl\|CDD\|223297
CP029653.1\|AWQ89901.1\|2099167_2100205_-\|A/G-specific-adenine-glycosylase	unknown	unknown	gnl\|CDD\|224115
CP029653.1\|AWQ89448.1\|2101594_2102431_-\|putative-membrane-protein	unknown	unknown	gnl\|CDD\|224596
CP029653.1\|AWQ89963.1\|2076124_2076241_+\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ88565.1\|2075404_2075800_-\|putative-membrane-protein	unknown	unknown	unknown
CP029653.1\|AWQ88270.1\|2076400_2076553_-\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ88688.1\|2079088_2079811_-\|recF/RecN/SMC-N-terminal-domain-protein	unknown	unknown	gnl\|CDD\|224051
CP029653.1\|AWQ89245.1\|2076577_2077177_-\|glucosamine-6-phosphate-isomerase-family-protein	unknown	unknown	gnl\|CDD\|223440
CP029653.1\|AWQ90024.1\|2093429_2094719_+\|glutamate-1-semialdehyde-2,1-aminomutase	unknown	unknown	gnl\|CDD\|183493
CP029653.1\|AWQ88336.1\|2091937_2092888_-\|D-isomer-specific-2-hydroxyacid-dehydrogenase,-NAD-binding-domain-protein	unknown	unknown	gnl\|CDD\|240632
CP029653.1\|AWQ87584.1\|2100356_2101334_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224899
CP029653.1\|AWQ87931.1\|2079803_2081261_-\|amino-ABC-transporter,-permease,-3-TM-region,-His/Glu/Gln/Arg/opine-family-domain-protein	unknown	unknown	gnl\|CDD\|223836
CP029653.1\|AWQ88431.1\|2091394_2091841_-\|peroxide-responsive-repressor-PerR	unknown	unknown	gnl\|CDD\|223806
CP029653.1\|AWQ89412.1\|2092893_2093349_-\|ahpC/TSA-family-protein	unknown	unknown	gnl\|CDD\|224146

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ88872.1\|2073823_2075209_-\|fumarate-hydratase,-class-II	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
CP029653.1\|AWQ89582.1\|2095011_2096106_+\|hypothetical-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	1.5476e-86
CP029653.1\|AWQ87832.1\|2098322_2098865_-\|hypothetical-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	1.0244e-125
CP029653.1\|AWQ90024.1\|2093429_2094719_+\|glutamate-1-semialdehyde-2,1-aminomutase	gnl\|CDD\|183493	PRK12389, PRK12389, glutamate-1-semialdehyde aminotransferase; Provisional.	0
CP029653.1\|AWQ87508.1\|2096296_2097943_-\|putative-multidrug-export-ATP-binding/permease-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
CP029653.1\|AWQ88362.1\|2081519_2082581_-\|phosphotransferase-system,-EIIC-family-protein	gnl\|CDD\|226167	COG3641, PfoR, Predicted membrane protein, putative toxin regulator [General function prediction only].	1.65132e-122
CP029653.1\|AWQ87522.1\|2077335_2077806_-\|tRNA-(cytidine(34)-2'-O)-methyltransferase	gnl\|CDD\|223297	COG0219, CspR, Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis].	1.70324e-88
CP029653.1\|AWQ89448.1\|2101594_2102431_-\|putative-membrane-protein	gnl\|CDD\|224596	COG1682, TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane].	0.000164936
CP029653.1\|AWQ89901.1\|2099167_2100205_-\|A/G-specific-adenine-glycosylase	gnl\|CDD\|224115	COG1194, MutY, A/G-specific DNA glycosylase [DNA replication, recombination, and repair].	4.67816e-157
CP029653.1\|AWQ89412.1\|2092893_2093349_-\|ahpC/TSA-family-protein	gnl\|CDD\|224146	COG1225, Bcp, Peroxiredoxin [Posttranslational modification, protein turnover, chaperones].	1.18155e-68
CP029653.1\|AWQ87931.1\|2079803_2081261_-\|amino-ABC-transporter,-permease,-3-TM-region,-His/Glu/Gln/Arg/opine-family-domain-protein	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	2.55367e-98
CP029653.1\|AWQ88688.1\|2079088_2079811_-\|recF/RecN/SMC-N-terminal-domain-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	4.70748e-153
CP029653.1\|AWQ89245.1\|2076577_2077177_-\|glucosamine-6-phosphate-isomerase-family-protein	gnl\|CDD\|223440	COG0363, NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism].	9.77274e-11
CP029653.1\|AWQ88336.1\|2091937_2092888_-\|D-isomer-specific-2-hydroxyacid-dehydrogenase,-NAD-binding-domain-protein	gnl\|CDD\|240632	cd12155, PGDH_1, Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family. Phosphoglycerate Dehydrogenase (PGDH) catalyzes the NAD-dependent conversion of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first step in serine biosynthesis. Over-expression of PGDH has been implicated as supporting proliferation of certain breast cancers, while PGDH deficiency is linked to defects in mammalian central nervous system development. PGDH is a member of the 2-hydroxyacid dehydrogenase family, enzymes that catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-Adenosylhomocysteine Hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	8.45391e-136
CP029653.1\|AWQ87584.1\|2100356_2101334_+\|hypothetical-protein	gnl\|CDD\|224899	COG1988, COG1988, Predicted membrane-bound metal-dependent hydrolases [General function prediction only].	1.21408e-39
CP029653.1\|AWQ88431.1\|2091394_2091841_-\|peroxide-responsive-repressor-PerR	gnl\|CDD\|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	6.09298e-56
CP029653.1\|AWQ88820.1\|2077810_2078938_-\|epoxyqueuosine-reductase	gnl\|CDD\|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	6.7316e-180

>CP029653.1|AWQ88362.1|2081519_2082581_-|phosphotransferase-system,-EIIC-family-protein
MSNAKNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSGNEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSFMLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRKITQAIGNVIHSFTDLNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLGIVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAYVLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAFIVHELCKKFIPIYSNDIYKFEVPKQ
>CP029653.1|AWQ87931.1|2079803_2081261_-|amino-ABC-transporter,-permease,-3-TM-region,-His/Glu/Gln/Arg/opine-family-domain-protein
MKCLIRFILVLGLLISSAMVYINPAAYAEQDQKWEKIKERGELRVGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTGKIDIIISGMTSTPERKKQVDFSDSYMMTKNIMLVKKDKVNDYKDIKDFNNKKVGAQKGTEQEKIAQTEIENASITSLSRLPDVILALKSGKVEGVVVEKPVAEAYLKQNPKLGISNVKFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKYGSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPMLVQVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLGLNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFDPFTPLLVAAALYFVLTFVLTRIMNMIEGRLNASD
>CP029653.1|AWQ88688.1|2079088_2079811_-|recF/RecN/SMC-N-terminal-domain-protein
MIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLLRCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAPKLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILFDEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESGTPVEIFEQPQHERTQNFLARVL
>CP029653.1|AWQ88820.1|2077810_2078938_-|epoxyqueuosine-reductase
MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANGYASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWGQDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVINPKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFLTQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLRMSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRATAYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE
>CP029653.1|AWQ87522.1|2077335_2077806_-|tRNA-(cytidine(34)-2'-O)-methyltransferase
MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKMLKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIFGKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN
>CP029653.1|AWQ89245.1|2076577_2077177_-|glucosamine-6-phosphate-isomerase-family-protein
MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAPVLDELKKNIEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKIKTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGKTSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA
>CP029653.1|AWQ88270.1|2076400_2076553_-|hypothetical-protein
MSKDKDPKLNYHEEENSMVTDFEDLKELGKEMEQISDQNDQEKNSEEDSQ
>CP029653.1|AWQ89963.1|2076124_2076241_+|hypothetical-protein
MELDFQFLLTLQVGERPQHSEIGFPISTDIASWGTGPT
>CP029653.1|AWQ88565.1|2075404_2075800_-|putative-membrane-protein
MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPIIFKVIKLQLNLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVALNPYTTIVSAVLYILTAIATVEATKTKYRN
>CP029653.1|AWQ88872.1|2073823_2075209_-|fumarate-hydratase,-class-II
MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPVEVVYGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSNMNVNEVVSYVANMYLKDHHSDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEPALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCETMLSESKKHILNLAIGGTAVGTGINAHPEFGDKVAQYISENTGYPFVSSENKFHALTAHDEVVQLHGTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMVAVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPIEENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEAWIKPEDMVDPH
>CP029653.1|AWQ88431.1|2091394_2091841_-|peroxide-responsive-repressor-PerR
MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHPTADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIICEQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK
>CP029653.1|AWQ88336.1|2091937_2092888_-|D-isomer-specific-2-hydroxyacid-dehydrogenase,-NAD-binding-domain-protein
MKVVGLNRMREVETELQQRFSDVDFKFYKKASEIPESDLANLDILVGYDGGINEAFLRRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQAKQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFNMNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIVINALPETQETIHLLKKKHFELMKDEALFINIGRGSIVKEALLIEVLKSRVIRHAYLDVFENEPLKPNHELYELDNVTITAHITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDAKKGY
>CP029653.1|AWQ89412.1|2092893_2093349_-|ahpC/TSA-family-protein
MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIVYFYPRDNTPTCTTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKHGLNFDLLVDEDFKLAKETGVYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG
>CP029653.1|AWQ90024.1|2093429_2094719_+|glutamate-1-semialdehyde-2,1-aminomutase
MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHGAYLYDVDGNKFIDYLQAYGPIITGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSKKLRDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGPSQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMPQPGFLEEVNEISHSNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPIGGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQLEEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQGINLAPSKFEAWFLTTEHTEEDIKQTLKAADYAFSQMK
>CP029653.1|AWQ89582.1|2095011_2096106_+|hypothetical-protein
MRLGARIFKTGIAIILAMSIASLLPDDVGLKALAGVSAVVAMQPSIYRSFKTVSDQALGNIIGAILSVTMVTIFSDNFIIMGVTVIVLIAILFKFNLAHVATLASVTALIIMGQHTGSFYITAFYRFVLVMIGVISSSLVNFVFLPPKFETKIYYNSLNISSDIFMWFKLVLNDTTEFNNIKQDSHNLKQRVEKLEKIYDYYSEERPITKKHIHQQNRKKILFREVVQTTRQAYEVLNKLSRYQNDLYLLNNNFLLQIKLDLDSLTAFHEQILASLSKKARYNVTHVDYELDNPQKKDLLSTFQHELINHPYQTEYSFANVMQIVAAIEEYRHHLEHLDRIRISFFTYHRSDADIEIVEEDFDL
>CP029653.1|AWQ87508.1|2096296_2097943_-|putative-multidrug-export-ATP-binding/permease-protein
MLIPLLIKYAIDGVINNHALTTDEKVHHLTIAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYNHLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFFLDVKLTLAALFIFPFYILTVYVFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAIEDNEAKNFDKKNTNFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGSITVGTLAAFVGYLELLFGPLRRLVASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPIEIKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVGMSGGGKSTLINLIPRFYDVTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKENILLGRPTATDEEVVEAAKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSALDLESESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGHIVETGTHRELIAKQGAYEHLYSIQNL
>CP029653.1|AWQ87832.1|2098322_2098865_-|hypothetical-protein
MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGGNDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEALKYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKGPFAPDFIKVWKDRYKKIRQY
>CP029653.1|AWQ89901.1|2099167_2100205_-|A/G-specific-adenine-glycosylase
MYQQSSFKENLIHWFDENQREMPWRQTTNPYYIWLSEVMLQQTQVKTVIDYYHRFVERFPTVEVLSQASEDEVLKYWEGLGYYSRARNFHTAIKEVHDKYEGLVPKDPDQFKALKGVGPYTQAAVMSIAYNVPLATVDGNVFRVWSRLNDDYRDIKLQSTRKSYEQELLPYVTTEAGTFNQAMMELGALICTPKNPLCLFCPVQENCEAFDKGTFEKLPVKSKNVSKKVIEQSVFLIRNNQGQYLLQKRSEKLLHGMWQFPMFKSEHARREMTEKIGHDIQPVETPIFELKHQFTHLTWKIKVYAVSGTINIERLPDDMIWFDLSDRDQYTFPVPMSKIYQFING
>CP029653.1|AWQ87584.1|2100356_2101334_+|hypothetical-protein
MDTATHIAIGVGLTALATQDPAMASTFGATATTLIVGSLIPDGDTVLKLKDNATYISHHRGITHSIPFTILWPILITFLIFTFFSGTHPFHVWMWAQLAVFLHVFVDIFNSYGTQALRPITNKWIQLSVINTFDPIIFTVLCIGIVLWVVGLHPLAVFFPIIALLIIYYMIRFKMRAVIKQQALKAIQQEHHPVKVFVAPTIKFMEWRVAIQTDAHDYVGKAYGRNVVFSDKVERQKLSTDSILWKVKGNKDIRTFLNFSSIYRWQTTTLADGSTEIRLIDLRYLKNDHYSFVAIAHVTKDNVIDHSYIGWVFTEDKLQRKLYAK
>CP029653.1|AWQ89448.1|2101594_2102431_-|putative-membrane-protein
MLDNIILYFKNLPHTKRYVTERLKQSWKSFLIVLAACLILIIASETLFSFSHLTDVKEVRWLFRLIALIVFAVLMFTIYISYHHYMNDFLVTKLFNISAATPVVIMSILSFIMLVILTMISALVKPVNFETSYIALFYFIVMATIFVGLISVTFGLIRLLTEKINIIFYGICVLCFLVLPIIFIPNPNHVFINHILMLNPMYYIVNGIAQSIIFGISSMENIPYHFYFILFLCLIAAVNFVLARYTTHAIYNKTSKVTQTDNQQDVSKDSTDEADTSS

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Crispr_ID: CP029653_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_8

2117480-2117564

Orphan

Consensus_repeat	Method
TCTGTGTTGGGGCCTACACCCCAAC	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of CP029653_8

>merge|CP029653|8|2117480-2117564|CRISPRCasFinder
TCTGTGTTGGGGCCTACACCCCAACCTGCATTGCCTGTAGAATTTCTTTTTTCGAAATTCTCTGTGTTGGGGCCCACACCCCAAC

>CP029653|8|8|2117480-2117564|CRISPRCasFinder
TCTGTGTTGGGGCCTACACCCCAAC	CTGCATTGCCTGTAGAATTTCTTTTTTCGAAATTC
TCTGTGTTGGGGCCCACACCCCAAC

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ87879.1\|2122100_2122601_+\|ferritin	unknown	unknown	gnl\|CDD\|224445
CP029653.1\|AWQ88172.1\|2109553_2110801_-\|thermophilic-metalloprotease-family-protein	unknown	unknown	gnl\|CDD\|376723
CP029653.1\|AWQ87521.1\|2115172_2115874_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227100
CP029653.1\|AWQ88706.1\|2115888_2116275_-\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ88944.1\|2119762_2120494_-\|cobB/CobQ-like-glutamine-amidotransferase-domain-protein	unknown	unknown	gnl\|CDD\|225974
CP029653.1\|AWQ89962.1\|2123612_2124683_-\|impB/mucB/samB-family-protein	unknown	unknown	gnl\|CDD\|235035
CP029653.1\|AWQ89684.1\|2113513_2114143_-\|response-regulator	unknown	unknown	gnl\|CDD\|225107
CP029653.1\|AWQ88799.1\|2119124_2119577_-\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ89988.1\|2110812_2111013_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227177
CP029653.1\|AWQ88729.1\|2111159_2111624_+\|low-molecular-weight-protein-tyrosine-phosphatase-PtpA	unknown	unknown	gnl\|CDD\|319971
CP029653.1\|AWQ89759.1\|2122991_2123546_+\|exonuclease-family-protein	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP029653.1\|AWQ88477.1\|2124929_2125460_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378690
CP029653.1\|AWQ89764.1\|2125629_2126991_-\|23S-rRNA-(uracil-5-)-methyltransferase-RumA	unknown	unknown	gnl\|CDD\|225174
CP029653.1\|AWQ89299.1\|2112183_2113401_+\|yihY-family-inner-membrane-domain-protein	unknown	unknown	gnl\|CDD\|224214
CP029653.1\|AWQ87388.1\|2111630_2111906_+\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ87629.1\|2114132_2115176_-\|sensor-protein-VraS	unknown	unknown	gnl\|CDD\|226951
CP029653.1\|AWQ89511.1\|2117949_2118936_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226614
CP029653.1\|AWQ88365.1\|2116491_2117250_-\|methionine-aminopeptidase,-type-I	unknown	unknown	gnl\|CDD\|235576
CP029653.1\|AWQ88243.1\|2120495_2121809_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223840
CP029653.1\|AWQ89204.1\|2127071_2128019_-\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ87879.1\|2122100_2122601_+\|ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	1.15329e-74
CP029653.1\|AWQ88172.1\|2109553_2110801_-\|thermophilic-metalloprotease-family-protein	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
CP029653.1\|AWQ87521.1\|2115172_2115874_-\|hypothetical-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
CP029653.1\|AWQ88944.1\|2119762_2120494_-\|cobB/CobQ-like-glutamine-amidotransferase-domain-protein	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.79354e-120
CP029653.1\|AWQ89962.1\|2123612_2124683_-\|impB/mucB/samB-family-protein	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP029653.1\|AWQ89684.1\|2113513_2114143_-\|response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	1.75115e-79
CP029653.1\|AWQ89204.1\|2127071_2128019_-\|diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
CP029653.1\|AWQ89988.1\|2110812_2111013_-\|hypothetical-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.24488e-25
CP029653.1\|AWQ88729.1\|2111159_2111624_+\|low-molecular-weight-protein-tyrosine-phosphatase-PtpA	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	5.12846e-65
CP029653.1\|AWQ89759.1\|2122991_2123546_+\|exonuclease-family-protein	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
CP029653.1\|AWQ88477.1\|2124929_2125460_-\|hypothetical-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.54005e-11
CP029653.1\|AWQ89764.1\|2125629_2126991_-\|23S-rRNA-(uracil-5-)-methyltransferase-RumA	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
CP029653.1\|AWQ89299.1\|2112183_2113401_+\|yihY-family-inner-membrane-domain-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	2.99224e-85
CP029653.1\|AWQ87629.1\|2114132_2115176_-\|sensor-protein-VraS	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
CP029653.1\|AWQ89511.1\|2117949_2118936_+\|hypothetical-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	9.69605e-76
CP029653.1\|AWQ88365.1\|2116491_2117250_-\|methionine-aminopeptidase,-type-I	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
CP029653.1\|AWQ88243.1\|2120495_2121809_-\|hypothetical-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.60835e-98

>CP029653.1|AWQ88365.1|2116491_2117250_-|methionine-aminopeptidase,-type-I
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>CP029653.1|AWQ88706.1|2115888_2116275_-|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMHYLITKKEQLSKLIDSLMLTLENKYIDIVEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>CP029653.1|AWQ87521.1|2115172_2115874_-|hypothetical-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>CP029653.1|AWQ87629.1|2114132_2115176_-|sensor-protein-VraS
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>CP029653.1|AWQ89684.1|2113513_2114143_-|response-regulator
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>CP029653.1|AWQ89299.1|2112183_2113401_+|yihY-family-inner-membrane-domain-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIVFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDTNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>CP029653.1|AWQ87388.1|2111630_2111906_+|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>CP029653.1|AWQ88729.1|2111159_2111624_+|low-molecular-weight-protein-tyrosine-phosphatase-PtpA
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIQDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>CP029653.1|AWQ89988.1|2110812_2111013_-|hypothetical-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>CP029653.1|AWQ88172.1|2109553_2110801_-|thermophilic-metalloprotease-family-protein
MTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYRCGASDVRVVYSDPTLKRLKFENESVEHFANHEIKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF
>CP029653.1|AWQ89511.1|2117949_2118936_+|hypothetical-protein
MNGQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQEIILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>CP029653.1|AWQ88799.1|2119124_2119577_-|hypothetical-protein
MQHEKMNDERNLTMKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSVTFEDQEIKFEFALFDSDMDNLKYIEYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMVTESGVSLRINVTKSGFTKFINELVSLH
>CP029653.1|AWQ88944.1|2119762_2120494_-|cobB/CobQ-like-glutamine-amidotransferase-domain-protein
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHNFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEKQAKQVLIDRANRQKKSR
>CP029653.1|AWQ88243.1|2120495_2121809_-|hypothetical-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNGDDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISRFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQAIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP029653.1|AWQ87879.1|2122100_2122601_+|ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEEAMFETHINYLTRIGDDSNALYLYEKELGTRTFDEE
>CP029653.1|AWQ89759.1|2122991_2123546_+|exonuclease-family-protein
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>CP029653.1|AWQ89962.1|2123612_2124683_-|impB/mucB/samB-family-protein
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYRNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSTRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP029653.1|AWQ88477.1|2124929_2125460_-|hypothetical-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSAGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>CP029653.1|AWQ89764.1|2125629_2126991_-|23S-rRNA-(uracil-5-)-methyltransferase-RumA
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMGSCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMVIFVTNGKNWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPSTQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>CP029653.1|AWQ89204.1|2127071_2128019_-|diacylglycerol-kinase
MRKRARIIYNPTSGKEQFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE

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Crispr_ID: CP029653_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_9

2128162-2128465

Orphan

Consensus_repeat	Method
NTCTNTGTTNGGGNCCCNNC	CRT

5 spacers

DEDDh

The CRISPR arrays of CP029653_9

>merge|CP029653|9|2128162-2128465|CRT
TCTATGTTTGGGGCCCCACCCCAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGCTTCTATGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAATTTCTTTTCAAAATTCTCTATGTTTGGGGCCCCACCCCAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGCTTCTATGTTGGGGCCCCGCCAACTTGCATTGTCTGTAGAATTTCCTTTCGAAATTCTCTTTGTTGGGGCCCCACCCTAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGCTTCTTTGTTGGGGCCCCAC

>CP029653|9|3|2128162-2128465|CRT
TCTATGTTTGGGGCCCCAC	CCCAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGCT
TCTATGTTGGGGCCCCGCC	AACTTGCATTGTCTGTAGAATTTCTTTTCAAAATTC
TCTATGTTTGGGGCCCCAC	CCCAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGC
TTCTATGTTGGGGCCCCGC	CAACTTGCATTGTCTGTAGAATTTCCTTTCGAAATT
CTCTTTGTTGGGGCCCCAC	CCTAACTTGCACATTATTGTAAGCTGACAGAAAGTCAGC
TTCTTTGTTGGGGCCCCAC

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ89759.1\|2122991_2123546_+\|exonuclease-family-protein	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP029653.1\|AWQ87879.1\|2122100_2122601_+\|ferritin	unknown	unknown	gnl\|CDD\|224445
CP029653.1\|AWQ87858.1\|2132523_2134062_+\|sodium/proline-symporter	unknown	unknown	gnl\|CDD\|273981
CP029653.1\|AWQ87930.1\|2128770_2128917_-\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ88944.1\|2119762_2120494_-\|cobB/CobQ-like-glutamine-amidotransferase-domain-protein	unknown	unknown	gnl\|CDD\|225974
CP029653.1\|AWQ88757.1\|2128955_2130383_-\|aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase,-B-subunit	unknown	unknown	gnl\|CDD\|235489
CP029653.1\|AWQ88382.1\|2137369_2139562_-\|ATP-dependent-DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
CP029653.1\|AWQ89204.1\|2127071_2128019_-\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
CP029653.1\|AWQ87684.1\|2130395_2131853_-\|aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase,-A-subunit	unknown	unknown	gnl\|CDD\|234572
CP029653.1\|AWQ89962.1\|2123612_2124683_-\|impB/mucB/samB-family-protein	unknown	unknown	gnl\|CDD\|235035
CP029653.1\|AWQ88477.1\|2124929_2125460_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378690
CP029653.1\|AWQ89764.1\|2125629_2126991_-\|23S-rRNA-(uracil-5-)-methyltransferase-RumA	unknown	unknown	gnl\|CDD\|225174
CP029653.1\|AWQ88961.1\|2140433_2140736_-\|trp-repressor-family-protein	unknown	unknown	gnl\|CDD\|226893
CP029653.1\|AWQ89228.1\|2131854_2132157_-\|aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase,-C-subunit	unknown	unknown	gnl\|CDD\|178810
CP029653.1\|AWQ88799.1\|2119124_2119577_-\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ87955.1\|2135362_2137366_-\|DNA-ligase,-NAD-dependent	unknown	unknown	gnl\|CDD\|236137
CP029653.1\|AWQ89511.1\|2117949_2118936_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226614
CP029653.1\|AWQ88243.1\|2120495_2121809_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223840
CP029653.1\|AWQ89526.1\|2139558_2140251_-\|geranylgeranylglyceryl-phosphate-synthase-family-protein	unknown	unknown	gnl\|CDD\|224560
CP029653.1\|AWQ87462.1\|2134150_2135350_-\|camS-sex-pheromone-cAM373-family-protein	unknown	unknown	gnl\|CDD\|227188

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ89759.1\|2122991_2123546_+\|exonuclease-family-protein	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
CP029653.1\|AWQ88757.1\|2128955_2130383_-\|aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase,-B-subunit	gnl\|CDD\|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
CP029653.1\|AWQ87858.1\|2132523_2134062_+\|sodium/proline-symporter	gnl\|CDD\|273981	TIGR02121, Osmoregulated_proline_transporter, sodium/proline symporter. This family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores. [Transport and binding proteins, Amino acids, peptides and amines].	0
CP029653.1\|AWQ88944.1\|2119762_2120494_-\|cobB/CobQ-like-glutamine-amidotransferase-domain-protein	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	1.79354e-120
CP029653.1\|AWQ88382.1\|2137369_2139562_-\|ATP-dependent-DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
CP029653.1\|AWQ87879.1\|2122100_2122601_+\|ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	1.15329e-74
CP029653.1\|AWQ89204.1\|2127071_2128019_-\|diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
CP029653.1\|AWQ87684.1\|2130395_2131853_-\|aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase,-A-subunit	gnl\|CDD\|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
CP029653.1\|AWQ89962.1\|2123612_2124683_-\|impB/mucB/samB-family-protein	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP029653.1\|AWQ88477.1\|2124929_2125460_-\|hypothetical-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.54005e-11
CP029653.1\|AWQ89764.1\|2125629_2126991_-\|23S-rRNA-(uracil-5-)-methyltransferase-RumA	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0
CP029653.1\|AWQ88961.1\|2140433_2140736_-\|trp-repressor-family-protein	gnl\|CDD\|226893	COG4496, COG4496, Uncharacterized protein conserved in bacteria [Function unknown].	1.66593e-59
CP029653.1\|AWQ89228.1\|2131854_2132157_-\|aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase,-C-subunit	gnl\|CDD\|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	5.296e-34
CP029653.1\|AWQ87955.1\|2135362_2137366_-\|DNA-ligase,-NAD-dependent	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
CP029653.1\|AWQ89511.1\|2117949_2118936_+\|hypothetical-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	9.69605e-76
CP029653.1\|AWQ88243.1\|2120495_2121809_-\|hypothetical-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.60835e-98
CP029653.1\|AWQ89526.1\|2139558_2140251_-\|geranylgeranylglyceryl-phosphate-synthase-family-protein	gnl\|CDD\|224560	COG1646, COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold [General function prediction only].	2.53994e-99
CP029653.1\|AWQ87462.1\|2134150_2135350_-\|camS-sex-pheromone-cAM373-family-protein	gnl\|CDD\|227188	COG4851, CamS, Protein involved in sex pheromone biosynthesis [General function prediction only].	0

>CP029653.1|AWQ89204.1|2127071_2128019_-|diacylglycerol-kinase
MRKRARIIYNPTSGKEQFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE
>CP029653.1|AWQ89764.1|2125629_2126991_-|23S-rRNA-(uracil-5-)-methyltransferase-RumA
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMGSCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMVIFVTNGKNWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPSTQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>CP029653.1|AWQ88477.1|2124929_2125460_-|hypothetical-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSAGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>CP029653.1|AWQ89962.1|2123612_2124683_-|impB/mucB/samB-family-protein
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYRNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSTRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP029653.1|AWQ89759.1|2122991_2123546_+|exonuclease-family-protein
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>CP029653.1|AWQ87879.1|2122100_2122601_+|ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEEAMFETHINYLTRIGDDSNALYLYEKELGTRTFDEE
>CP029653.1|AWQ88243.1|2120495_2121809_-|hypothetical-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNGDDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISRFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYTVLRELGLNEQAIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP029653.1|AWQ88944.1|2119762_2120494_-|cobB/CobQ-like-glutamine-amidotransferase-domain-protein
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHNFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEKQAKQVLIDRANRQKKSR
>CP029653.1|AWQ88799.1|2119124_2119577_-|hypothetical-protein
MQHEKMNDERNLTMKPTKVILKDASYLHSKTSITFILKDVVIEEDNKIYYFDTSVTFEDQEIKFEFALFDSDMDNLKYIEYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMVTESGVSLRINVTKSGFTKFINELVSLH
>CP029653.1|AWQ89511.1|2117949_2118936_+|hypothetical-protein
MNGQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQEIILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA
>CP029653.1|AWQ87930.1|2128770_2128917_-|hypothetical-protein
MVADLDAIEGLFISIEVILLLTLFIVHVNGKNINFINALALIILRQTV
>CP029653.1|AWQ88757.1|2128955_2130383_-|aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase,-B-subunit
MHFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAYPGVLPVVNKRAVDWAMRAAMALNMEIATESKFDRKNYFYPDNPKAYQISQFDQPIGENGYIDIEVDGEIKRIGITRLHMEEDAGKSTHKGEYSLVDLNRQGTPLIEIVSEPDIRSPKEAYAYLEKLRSIIQYTGVSDVKMEEGSLRCDANISLRPYGQEKFGTKAELKNLNSFNYVRKGLEYEEKRQEEELLSGGEIGQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIVPLYIDDAWKERVRQTIPELPDERKAKYVNELGLPAYDAHVLTLTKEMSDFFESTIEHGADVKLTSNWLMGGVNEYLNKNQVELLDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPELAAKGGNAKQIMEDNGLVQISDEATLLKFVNEALDNNEQSVEDYKNGKGKAMGFLVGQIMKASKGQANPQLVNQLLKQELDKR
>CP029653.1|AWQ87684.1|2130395_2131853_-|aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase,-A-subunit
MSIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFLALDKENAIKKAQELDELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPIYESTVMEKLHNENAVLIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAAAVAAGLVPFSLGSDTGGSIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTRNVKDNAIVLEAISGADANDSTSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDVKEAVQNAVETLKSLGAVVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSKEAHSLEELYKMSRSEGFGKEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKVFENYDVVVGPTAPTTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRPIGLQFIGKPFDEKTLYRVAYQYETQYNLHDVYEKL
>CP029653.1|AWQ89228.1|2131854_2132157_-|aspartyl/glutamyl-tRNA(Asn/Gln)-amidotransferase,-C-subunit
MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDSADTEGVEPTYHVLDLQNVLREDKAIKGIPQELALKNAKETEDGQFKVPTIMNEEDA
>CP029653.1|AWQ87858.1|2132523_2134062_+|sodium/proline-symporter
MLTMGTALSQQVDANWQTYIMIAVYFLILIVIGFYGYKQATGNLSEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTGLSAMWITIGLTLGAYINYFVVAPRLRVYTELAGDAITLPDFFKNRLNDKNNVLKIISGLIIVVFFTLYTHSGFVSGGKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQGVIMLIAMVMVPIVAMMNLNGWGTFHDVAAMKPTNLNLFKGLSFIGIISLFSWGLGYFGQPHIIVRFMSIKSHKMLPKARRLGISWMAVGLLGAVAVGLTGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVGGFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLVRGEEKAKTHQKEFVMVGRLSVLAVAIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWKGLTRAGAVSGMVSGALVVIVWIAWIKPLAHINEIFGLYEIIPGFIVSVIVTYVVSKLTKKPGAFVETDLNKVRDIVREK
>CP029653.1|AWQ87462.1|2134150_2135350_-|camS-sex-pheromone-cAM373-family-protein
MKRTLVLLITAIFILAACGNHKDDQAGKDNQKHNNSSNQVKEIATDKNVQGDNYRTLLPFKESQARGLLQDNMANSYNGGDFEDGLLNLSKEVFPTDKYLYQDGQFLDKKTINAYLNPKYTKREIDKMSEKDKKDKKANENLGLNPSHEGETDPEKIAEKSPAYLSNILEQDFYGGGDTKGKNIKGMTIGLAMNSVYYYKKEKDGPTFSKKLDDSEVKKQGKQMASEILSRLRENDDLKDIPIHFAIYKQSSEDSITPGEFITQATAEKSQTKLNEWHNINEKSALLPSSTAADYDENLNNNFKQFNDNLQSYFSNFTQAVGKVKFVDKKPQRLVVDLPIDYYGQAETIGITQYVTEQANKYFDKIDNYEIRIKDGNQPRALISKTKDDKEPQVHIYSN
>CP029653.1|AWQ87955.1|2135362_2137366_-|DNA-ligase,-NAD-dependent
MADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIKIEEEHPEFKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVSDIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFPAEEVVTKLLDIELSIGRTGVVTPTAILEPVKVAGTTVSRASLHNEDLIHDRDIRIGDSVVVKKAGDIIPEVVRSIPERRPEDAVTYHMPTHCPSCGHELVRIEGEVALRCINPKCQAQLVEGLIHFVSRQAMNIDGLGTKIIQQLYQSELIKDVADIFYLTEEDLLPLDRMGQKKVDNLLAAIQQAKDNSLENLLFGLGIRHLGVKASQVLAEKYETIDRLLTVTEAELVEIHDIGDKVAQSVVTYLENEDIRALIQKLKDKHVNMIYKGIKTSDIEGHPEFSGKTIVLTGKLHQMTRNEASKWLASQGAKVTSSVTKNTDVVIAGEDAGSKLTKAQSLGIEIWTEQQFVDKQNELNS
>CP029653.1|AWQ88382.1|2137369_2139562_-|ATP-dependent-DNA-helicase-PcrA
MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADRIGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHVDEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIREIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSKKVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENIDEFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIVFIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVSSSDWNVGDKVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED
>CP029653.1|AWQ89526.1|2139558_2140251_-|geranylgeranylglyceryl-phosphate-synthase-family-protein
MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVTEDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVAFHNGTLLEALKTYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHLYRLPVMYIEYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKKALKTVKIKESSK
>CP029653.1|AWQ88961.1|2140433_2140736_-|trp-repressor-family-protein
MQIEKLRGAALDELFDAILTLENREECYQFFDDLCTVNEIQSLSQRLQVAKMIKQGYTYATIEQESGASTATISRVKRSLQWGNDAYTMILDRMNIETNE

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Crispr_ID: CP029653_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_10

2360741-2360830

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of CP029653_10

>merge|CP029653|10|2360741-2360830|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCAGTTGATGCGCAGCATCCAACTGTGTTCCTCTATTTTTCAACTTTAGTTGTTAGGGGCTTCT

>CP029653|10|9|2360741-2360830|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCAGTTGATGCGCAGCATCCAACTGTGTTCCTCTATTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ88730.1\|2371342_2372449_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
CP029653.1\|AWQ88351.1\|2361943_2362108_+\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ88069.1\|2370908_2371343_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	unknown	unknown	gnl\|CDD\|227014
CP029653.1\|AWQ89473.1\|2359632_2360724_+\|putative-membrane-protein	unknown	unknown	unknown
CP029653.1\|AWQ89250.1\|2358064_2358385_+\|HTH-type-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
CP029653.1\|AWQ89043.1\|2358386_2359367_+\|cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	unknown	unknown	gnl\|CDD\|224151
CP029653.1\|AWQ87437.1\|2363691_2364474_-\|ABC-transporter-family-protein	unknown	unknown	gnl\|CDD\|224044
CP029653.1\|AWQ87706.1\|2351230_2351941_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
CP029653.1\|AWQ88764.1\|2362766_2363624_-\|HAD-hydrolase,-IIB-family-protein	unknown	unknown	gnl\|CDD\|223635
CP029653.1\|AWQ89750.1\|2355612_2355843_-\|putative-membrane-protein	unknown	unknown	unknown
CP029653.1\|AWQ89215.1\|2368764_2370897_+\|PRD-domain-protein	unknown	unknown	gnl\|CDD\|226234
CP029653.1\|AWQ87513.1\|2352704_2353118_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225556
CP029653.1\|AWQ89795.1\|2367191_2368730_+\|PTS-system-mannitol-specific-EIICB-component	unknown	unknown	gnl\|CDD\|225123
CP029653.1\|AWQ88995.1\|2364705_2366511_-\|glutamine-fructose-6-phosphate-transaminase	unknown	unknown	gnl\|CDD\|234729
CP029653.1\|AWQ89399.1\|2372767_2379445_-\|sasC/Mrp/FmtB-intercellular-aggregation-domain-protein	unknown	unknown	gnl\|CDD\|275089
CP029653.1\|AWQ88469.1\|2357247_2357913_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187554
CP029653.1\|AWQ90109.1\|2361786_2361957_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226950
CP029653.1\|AWQ88908.1\|2352061_2352505_-\|DNA-protection-during-starvation-protein-1	unknown	unknown	gnl\|CDD\|223854
CP029653.1\|AWQ89438.1\|2353566_2354940_-\|EVE-domain-protein	unknown	unknown	gnl\|CDD\|376640
CP029653.1\|AWQ89495.1\|2355873_2356812_-\|mannose-6-phosphate-isomerase,-class-I	unknown	unknown	gnl\|CDD\|224399

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ88730.1\|2371342_2372449_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
CP029653.1\|AWQ88069.1\|2370908_2371343_+\|mannitol-specific-phosphotransferase-enzyme-IIA-component	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	3.63374e-61
CP029653.1\|AWQ89250.1\|2358064_2358385_+\|HTH-type-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
CP029653.1\|AWQ87437.1\|2363691_2364474_-\|ABC-transporter-family-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.75723e-107
CP029653.1\|AWQ87706.1\|2351230_2351941_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	5.58822e-156
CP029653.1\|AWQ89438.1\|2353566_2354940_-\|EVE-domain-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
CP029653.1\|AWQ89043.1\|2358386_2359367_+\|cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.23697e-107
CP029653.1\|AWQ89215.1\|2368764_2370897_+\|PRD-domain-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	9.39374e-67
CP029653.1\|AWQ87513.1\|2352704_2353118_-\|hypothetical-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	4.7919e-46
CP029653.1\|AWQ89795.1\|2367191_2368730_+\|PTS-system-mannitol-specific-EIICB-component	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
CP029653.1\|AWQ88995.1\|2364705_2366511_-\|glutamine-fructose-6-phosphate-transaminase	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
CP029653.1\|AWQ89399.1\|2372767_2379445_-\|sasC/Mrp/FmtB-intercellular-aggregation-domain-protein	gnl\|CDD\|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	8.15879e-86
CP029653.1\|AWQ88469.1\|2357247_2357913_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	7.27205e-48
CP029653.1\|AWQ90109.1\|2361786_2361957_+\|hypothetical-protein	gnl\|CDD\|226950	COG4584, COG4584, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000346631
CP029653.1\|AWQ88908.1\|2352061_2352505_-\|DNA-protection-during-starvation-protein-1	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
CP029653.1\|AWQ88764.1\|2362766_2363624_-\|HAD-hydrolase,-IIB-family-protein	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	1.15818e-59
CP029653.1\|AWQ89495.1\|2355873_2356812_-\|mannose-6-phosphate-isomerase,-class-I	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.00589e-128

>CP029653.1|AWQ89473.1|2359632_2360724_+|putative-membrane-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLVGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLVIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVITIILFVVIHAVILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>CP029653.1|AWQ89043.1|2358386_2359367_+|cadmium,-cobalt-and-zinc/H(+)-K(+)-antiporter
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALIAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVIATIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTIKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHSHHAHHHAHVH
>CP029653.1|AWQ89250.1|2358064_2358385_+|HTH-type-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>CP029653.1|AWQ88469.1|2357247_2357913_-|NAD-dependent-epimerase/dehydratase-family-protein
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFEGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGDQDIKDALTQFENETD
>CP029653.1|AWQ89495.1|2355873_2356812_-|mannose-6-phosphate-isomerase,-class-I
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAFEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNGRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>CP029653.1|AWQ89750.1|2355612_2355843_-|putative-membrane-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>CP029653.1|AWQ89438.1|2353566_2354940_-|EVE-domain-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>CP029653.1|AWQ87513.1|2352704_2353118_-|hypothetical-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFTTLKGEVGQQFFKQHPEAANKNSVILQKGDRIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFADNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>CP029653.1|AWQ88908.1|2352061_2352505_-|DNA-protection-during-starvation-protein-1
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>CP029653.1|AWQ87706.1|2351230_2351941_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNIFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>CP029653.1|AWQ90109.1|2361786_2361957_+|hypothetical-protein
MSPKDTTRFETKPDHQAQFDWKESINFKTKDNQRIPLYIGVLLLYYSRFIIMYDNE
>CP029653.1|AWQ88351.1|2361943_2362108_+|hypothetical-protein
MTMSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>CP029653.1|AWQ88764.1|2362766_2363624_-|HAD-hydrolase,-IIB-family-protein
MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLATGRSHSEIHQLVPEDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIEHFGINQKETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>CP029653.1|AWQ87437.1|2363691_2364474_-|ABC-transporter-family-protein
MLIQLDQVGRMKQGKTILKNISWQINEGDKWILYGLNGAGKTTLLNILNAYEPATTGYVNLFGKMPGKVGYSTETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>CP029653.1|AWQ88995.1|2364705_2366511_-|glutamine-fructose-6-phosphate-transaminase
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVTLQLISYYAALHRDLDVDKPRNLAKSVTVE
>CP029653.1|AWQ89795.1|2367191_2368730_+|PTS-system-mannitol-specific-EIICB-component
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWFPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFFGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLATLVSFVVAALIMKFTKEPKQDLEAATAQMETTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSLDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>CP029653.1|AWQ89215.1|2368764_2370897_+|PRD-domain-protein
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRITGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNLAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVKKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETRDKSSNMIDKDDVHIETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLISDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>CP029653.1|AWQ88069.1|2370908_2371343_+|mannitol-specific-phosphotransferase-enzyme-IIA-component
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVYSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEGNVDRIVQAKSAEEIKQVFEEADA
>CP029653.1|AWQ88730.1|2371342_2372449_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALATGHQYDVILADESKTTTRVNNVAAINSMQPSEELKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLAYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>CP029653.1|AWQ89399.1|2372767_2379445_-|sasC/Mrp/FmtB-intercellular-aggregation-domain-protein
MFDKNNPQNYQARGNVAALGRVNANDSTDHGNFNGISKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLEFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQNANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDDSHYTTASIAEYNKLKQQADTILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAISELDAKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTAQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTAPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLDRVKNEEIFKIENITDSTQTKMDAYNEVKQAATARKAQNATVSNATDEEVAEADAAVDAAQTEGLHDIQVVKSKQEVADTKAKVLDKINAIQTQARVKPAADREVDNAYNTRKQEIQNSNTSTTEEKEAAYTQLDAKKQEARTNLDAANTNSAVTTAKDNGIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVNANADIDNAAANNDVDNAKTTNEATIAAITPDANVKPQAKQAIADKVQAQETAIDANNGATTEEKTAAKQQVQTEKTTADTAIDGAHSNAEVEAAKNAEIAKIEAIQPATTTKDDAKQAIATKANERKAAIAQTQEITAEEIAAANANVDNAVTEANNHIETANSQNEVDQAKTTGEASIDQVTPTVNKKATARNEITTILNNKLQAIQATPDATDEEKQAAETEANTENAKANQAITAATTNAEVDEAKTNAEAAINAVTPKVMKKQAAKDEIDQLQAAQTAVINNDQNATNEEKEAAIQQLATAVTDAKNNITAATDNNGVDTAKDAGKNSIQSTQPATAVKSNAKNEVDQAVTTQNQAIDNTTGATTEEKNAAKDLVSKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTIKDVAKDELATKAKEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAKSIDDVNTAKDNAIQAIDPIQASTDVKTNARAELLNEMQNKITEILNDNTTTNEEKGKDIEPVRAAYEEGLNNINAATTTGDVTTAKDTAVQKVQQLHANPVKKPAGKTELDQAAADKKTQIEQTPNASQQEINDAKQEVDAALNQAKTNIDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIADAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNILADTNATQDEKQQAIKQVDQNVQTALESINNGVDNSDVDDALTQGKATIDAVQVDATVKPKANQAIDAKAQETKESIDQSDQLTAEEKTAALATIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPVVKKNALEAIREVVNKQIEIIENADADASAKEIARTDLGRYFDRFADKLDKTQTNTEVDELQNVTIPAIEAIVPQKDPNANDTNSGSDNNDATANSNANATPENTGQPNVTESTDNANADTSSTTTNNHNDAATGGTTATSTDNSATGNGTSDKSEVESTNNGTTDKSATETDNATPAEIARNNNSTTATNENAPTGSTATVPTTNASTGAASSADSKDNASVNDSKQNAEVNNSAESQSTNGKVAQPKSENKAKDEKDGRDSTNQSMVESTTETLPSADITEPKVPSNTEKDKKESTTNQTDAGQLKSETNVASNEADKSEGNVDTDVSNKPSTSKPSEAKDKATSTEDSQKADMATSDKKDNQAAIGATADVNNKATQNDGANASPATVSNGSNSANQDMLKVTNTDKHQAKATSAQQGKENKAKQQAKTLPDTGMSHNDDLPYVELALGAGMAFLIRRFTKKDQQTEE

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Crispr_ID: CP029653_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_11

2438286-2438411

Orphan

Consensus_repeat	Method
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029653_11

>merge|CP029653|11|2438286-2438411|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCACTGGTTTCTCATGATTTTTTAATGTTTTTATTTTGAGTTACTCGAAAATTTTCCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA

>CP029653|11|10|2438286-2438411|CRISPRCasFinder
CCTCTTTACTCGAAAGCTCACAAAACTCTTGATATCA	CTGGTTTCTCATGATTTTTTAATGTTTTTATTTTGAGTTACTCGAAAATTTT
CCTCTTTACTCGAAAGCTCACAAAACCCTTGATATCA

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ87665.1\|2427115_2427964_-\|aldo/keto-reductase-family-protein	unknown	unknown	gnl\|CDD\|381359
CP029653.1\|AWQ87747.1\|2428856_2431283_+\|polysaccharide-lyase-family-8,-N-terminal-alpha-helical-domain-protein	unknown	unknown	gnl\|CDD\|238517
CP029653.1\|AWQ88317.1\|2433517_2433943_+\|MAP-domain-protein	unknown	unknown	gnl\|CDD\|367591
CP029653.1\|AWQ89223.1\|2442150_2442957_-\|cobalt-transport-family-protein	unknown	unknown	gnl\|CDD\|223692
CP029653.1\|AWQ90075.1\|2445014_2445803_-\|integrase-core-domain-protein	unknown	unknown	gnl\|CDD\|222853
CP029653.1\|AWQ87769.1\|2440665_2441103_-\|ribosomal-protein-L13	unknown	unknown	gnl\|CDD\|181703
CP029653.1\|AWQ90071.1\|2440253_2440646_-\|30S-ribosomal-protein-S9	unknown	unknown	gnl\|CDD\|178888
CP029653.1\|AWQ87601.1\|2434333_2435038_-\|alpha-acetolactate-decarboxylase	unknown	unknown	gnl\|CDD\|226058
CP029653.1\|AWQ87999.1\|2426769_2426895_-\|putative-membrane-protein	unknown	unknown	unknown
CP029653.1\|AWQ89202.1\|2438468_2439905_-\|marR-family-protein	unknown	unknown	gnl\|CDD\|225420
CP029653.1\|AWQ90090.1\|2435074_2436739_-\|acetolactate-synthase,-catabolic	unknown	unknown	gnl\|CDD\|236312
CP029653.1\|AWQ87500.1\|2432407_2433223_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319792
CP029653.1\|AWQ88889.1\|2443803_2444613_-\|ABC-transporter-family-protein	unknown	unknown	gnl\|CDD\|184207
CP029653.1\|AWQ89248.1\|2428033_2428450_-\|merR-regulatory-family-protein	unknown	unknown	gnl\|CDD\|133384
CP029653.1\|AWQ87952.1\|2438040_2438220_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236623
CP029653.1\|AWQ88470.1\|2442946_2443807_-\|energy-coupling-factor-transporter-ATP-binding-protein-EcfA-1	unknown	unknown	gnl\|CDD\|184205
CP029653.1\|AWQ90110.1\|2441351_2442146_-\|tRNA-pseudouridine(38-40)-synthase	unknown	unknown	gnl\|CDD\|234577
CP029653.1\|AWQ87882.1\|2446808_2447177_-\|ribosomal-protein-L17	unknown	unknown	gnl\|CDD\|235522
CP029653.1\|AWQ87763.1\|2445826_2446555_-\|helix-turn-helix-domain-protein	unknown	unknown	gnl\|CDD\|379233
CP029653.1\|AWQ89416.1\|2431342_2432197_-\|peptidase-M23-family-protein	unknown	unknown	gnl\|CDD\|366703

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ87665.1\|2427115_2427964_-\|aldo/keto-reductase-family-protein	gnl\|CDD\|381359	cd19133, AKR_AKR5F1, the AKR5F family of aldo-keto reductase (AKR). Klebsiella sp. 2,5-diketo-D-gluconic acid reductase (2,5-DKG reductase) is a founding member of aldo-keto reductase family 5 member F1 (AKR5F1). It catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG).	3.15275e-150
CP029653.1\|AWQ87747.1\|2428856_2431283_+\|polysaccharide-lyase-family-8,-N-terminal-alpha-helical-domain-protein	gnl\|CDD\|238517	cd01083, GAG_Lyase, Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.	0
CP029653.1\|AWQ88317.1\|2433517_2433943_+\|MAP-domain-protein	gnl\|CDD\|367591	pfam03642, MAP, MAP domain. This presumed 110 amino acid residue domain is found in multiple copies in MAP (MHC class II analogue protein). The protein has been found in a wide range of extracellular matrix proteins.	8.17372e-34
CP029653.1\|AWQ90075.1\|2445014_2445803_-\|integrase-core-domain-protein	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.91633e-47
CP029653.1\|AWQ87769.1\|2440665_2441103_-\|ribosomal-protein-L13	gnl\|CDD\|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	4.91074e-100
CP029653.1\|AWQ87952.1\|2438040_2438220_-\|hypothetical-protein	gnl\|CDD\|236623	PRK09775, PRK09775, type II toxin-antitoxin system HipA family toxin YjjJ.	0.0004492
CP029653.1\|AWQ87601.1\|2434333_2435038_-\|alpha-acetolactate-decarboxylase	gnl\|CDD\|226058	COG3527, AlsD, Alpha-acetolactate decarboxylase [Secondary metabolites biosynthesis, transport, and catabolism].	1.39507e-119
CP029653.1\|AWQ89223.1\|2442150_2442957_-\|cobalt-transport-family-protein	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	2.81787e-49
CP029653.1\|AWQ89202.1\|2438468_2439905_-\|marR-family-protein	gnl\|CDD\|225420	COG2865, COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription].	1.62674e-63
CP029653.1\|AWQ90090.1\|2435074_2436739_-\|acetolactate-synthase,-catabolic	gnl\|CDD\|236312	PRK08617, PRK08617, acetolactate synthase AlsS.	0
CP029653.1\|AWQ87500.1\|2432407_2433223_-\|hypothetical-protein	gnl\|CDD\|319792	cd02605, HAD_SPP, sucrose-phosphatase, similar to Synechocystis sp PCC 6803 SPP. Sucrose-phosphatase (SPP; EC 3.1.3.24) catalyzes the dephosphorylation of sucrose-6(F)-phosphate (Suc6P)-the final step in the pathway of sucrose biosynthesis in plants and cyanobacteria. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.06188e-100
CP029653.1\|AWQ88889.1\|2443803_2444613_-\|ABC-transporter-family-protein	gnl\|CDD\|184207	PRK13648, cbiO, cobalt transporter ATP-binding subunit; Provisional.	0
CP029653.1\|AWQ89248.1\|2428033_2428450_-\|merR-regulatory-family-protein	gnl\|CDD\|133384	cd01109, HTH_YyaN, Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB. Putative helix-turn-helix (HTH) MerR-like transcription regulators of Bacillus subtilis, YyaN and YraB, and related proteins; N-terminal domain. Based on sequence similarity, these proteins are predicted to function as transcription regulators that mediate responses to stress in eubacteria. They belong to the MerR superfamily of transcription regulators that promote transcription of various stress regulons by reconfiguring the operator sequence located between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their N-terminal domains are homologous and contain a DNA-binding winged HTH motif, while the C-terminal domains are often dissimilar and bind specific coactivator molecules such as metal ions, drugs, and organic substrates.	5.51415e-41
CP029653.1\|AWQ90071.1\|2440253_2440646_-\|30S-ribosomal-protein-S9	gnl\|CDD\|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	1.87986e-83
CP029653.1\|AWQ88470.1\|2442946_2443807_-\|energy-coupling-factor-transporter-ATP-binding-protein-EcfA-1	gnl\|CDD\|184205	PRK13646, cbiO, energy-coupling factor transporter ATPase.	0
CP029653.1\|AWQ90110.1\|2441351_2442146_-\|tRNA-pseudouridine(38-40)-synthase	gnl\|CDD\|234577	PRK00021, truA, tRNA pseudouridine(38-40) synthase TruA.	1.21958e-120
CP029653.1\|AWQ87882.1\|2446808_2447177_-\|ribosomal-protein-L17	gnl\|CDD\|235522	PRK05591, rplQ, 50S ribosomal protein L17; Validated.	2.70058e-62
CP029653.1\|AWQ87763.1\|2445826_2446555_-\|helix-turn-helix-domain-protein	gnl\|CDD\|379233	pfam13518, HTH_28, Helix-turn-helix domain. This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding.	2.03349e-13
CP029653.1\|AWQ89416.1\|2431342_2432197_-\|peptidase-M23-family-protein	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.20929e-22

>CP029653.1|AWQ87952.1|2438040_2438220_-|hypothetical-protein
MTEIVEFLSDGKLASRLEIQETMGLQKSYTSELIAELKKLEIIGSEGRGPGTRYYLIRD
>CP029653.1|AWQ90090.1|2435074_2436739_-|acetolactate-synthase,-catabolic
MTDKKYTAADMVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGPELIVTRHEQNAAMMAQGIGRLTGKPGVVLVTSGPGVSNLTTGLLTATSEGDPVLALGGQVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFISIPQDVISSPVESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSADETNAIRKLVERTNLPVVETFQGAGVISRELENHFFGRVGLFRNQVGDELLRKSDLVVTIGYDPIEYEASNWNKELETQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISEKVDEPFINQQHLDELEQLRTHIDEETGIKATHEEGILHPVEIIESMQKVLTDDTTVTVDVGSHYIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSSQDLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGLRVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN
>CP029653.1|AWQ87601.1|2434333_2435038_-|alpha-acetolactate-decarboxylase
MASVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNGEVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEKMLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGAVVGFFTPELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIQDEDFINANIDYKDIADEIREAE
>CP029653.1|AWQ88317.1|2433517_2433943_+|MAP-domain-protein
MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKEMTMDGYHTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNQLASQRGVTTEKINNAQTATYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK
>CP029653.1|AWQ87500.1|2432407_2433223_-|hypothetical-protein
MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVITVVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEPFLFEDIEDILHHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDRRILEVLVRYANDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDSGNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY
>CP029653.1|AWQ89416.1|2431342_2432197_-|peptidase-M23-family-protein
MNKTNFGDYLNKSKSRKIYKIFDQNLKREFSYWQFRKLFKSYTWQSDVHELKVCTQNDGTIEQIWIDKANQFGVAVTWKDNSIIGFVMRPLINYDAIKNETTLKYAVPTTDCYEVFWGGDNELYNYHYLYPHQRYAIDLVIKENHKTYKNLGKVNADYFCFGKDIIAPANGTVEKVVNGVQDNSIGSTKESQFLGNYIVIKHAENEYSLIAHLQQYSIIVNEGQNVKYGDIIGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFINNRELIKGDVVCGLQGE
>CP029653.1|AWQ87747.1|2428856_2431283_+|polysaccharide-lyase-family-8,-N-terminal-alpha-helical-domain-protein
MTYRMKKWQKLSTITLLMAGVITLNGGEFRSIDKHQIAVADTNVQTTDYEKLRNIWLDVNYGYDKYDENNPDMKKKFEATENEAEKLLKEMKTESDRKYLWESSKDLDTKSADMTRTYRNIEKISEAMKHKNTKLKTDENKTKVKDALEWLHKNAYGKEPDKKVADLTSNFKNKTSRNTNLNWWDYEIGTPRALTNTLILLQEDFTDEEKKKYTAPIKTFAPDSDKILSSVGKSEPAKGGNLVDISKVKLLESIIEEDKDMMKKSIDSFNTVFTYAQNSATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPMIKETPFNDSNQNDTTLKSWIDDGFMPLIYKGEMMDLSRGRAISRENETSHSASATVMKSLLRLSDTMDKSTKAKYKKIVKTSVESDSSYKQTDYLSSYSDISKMKSLMEDSTISTNGLTQQLKIYNDMDRVTYHNKGLDFAFGLSMTSKNVARYESINGENLKGWHTGAGMSYLYNSDVKHYRDNFWATADMKRLAGTTTLDNEEPKSTDVKKSSKTFVGGTKFDDQHASIGMDFENQDKTLTAKKSYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKANDYKLYKDDTQTTNSDNQETNSLFLESTNSTQNNIGYHFLNESKITVKKESHTGKWSDINKSQKDIQKTDEYYEVTQKHSNTDSKYAYVLYPGLSKDVFKSKASKVTVVKQEDDFHVVKDNESVWAGINYSDSAKTFEINNTKVEVKAKGMFILTKKDDNTYECSFYNPESTNSVSDIESKISMTGYSIINKNTSTSNESGVRFELTK
>CP029653.1|AWQ89248.1|2428033_2428450_-|merR-regulatory-family-protein
MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDNDLNWIYLVKNLRNAGVSIESLIEFCRLAQLPKNENIQAQQKQILNKQLEELNENLKTIHDARDLLQYKIDNYDNHIAKINASDNHDDNVERLWERK
>CP029653.1|AWQ87665.1|2427115_2427964_-|aldo/keto-reductase-family-protein
MNHIEISKDVKIPVLGFGVFQIPQEQTAEAVKEAIKAGYRHIDTAQSYLNETEVGQGIEASGIDRSELFITTKVWIENVNYEDTIKSIERSLQRLNLDYIDLVLIHQPYNDVYGSWRALEELKETGKIKAIGVSNFGVDRIVDLGIHNQIQPQVNQIEINPFHQQEEQVAALQQENVVVEAWAPFAEGKNQLFQNQLLQAIADKYNKSIAQVILRWLVERDIVVLAKSVNPERMAQNLDIFDFELTEEDKQQIATLEESNSQFFSHADPEMIKALTSRELDV
>CP029653.1|AWQ87999.1|2426769_2426895_-|putative-membrane-protein
MTYIPFSIITLITGIIMHMTMYFVKFECRKMPLFMTIIFTI
>CP029653.1|AWQ89202.1|2438468_2439905_-|marR-family-protein
MTSSKYIEYLQTEVEGQLLDRKRASINPKDVAQHISAFANAEGGKLVIGIEDNGEISGFNHSKAKKKEVYIEAPFEHLYRIPKYTYEIIEVKKRDGTMDEILIFDIEPSYDAIITLKDDSVYLRINDKSRKLTHNQITNLEYDRGSRRFEEELVEYSSIEDVNEELVDEFKQLLNTNVDNEKLLKARGFMREGKLTVAGLLLFSNNINVYLPGARIRFMRYEGTKEESGTRLNIVKDITFDKALPVAIREARAFINTQLREYTFLGKEGRFVTLPEYPEFAWFEGMINSIVHRRYDNQGDHIRIKMFDDRLEISSPGALPASVTLENIKEERYSRNPKLAAALTQYKWVRESNEGVGRIFDEMKQYFLDDPVYSEPNNSSVQLALKNNIIARKKRETGRVSNIITPELFESLNEQQELIVRHLYNQGELTASKIANIIQRSVPTARKRLKELEEMNIISTHGSSKNDPKRTYYLLGFE
>CP029653.1|AWQ90071.1|2440253_2440646_-|30S-ribosomal-protein-S9
MAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFESLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKRAGLLTRDPRMKERKKPGLKAARRSPQFSKR
>CP029653.1|AWQ87769.1|2440665_2441103_-|ribosomal-protein-L13
MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKVTYTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLIENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG
>CP029653.1|AWQ90110.1|2441351_2442146_-|tRNA-pseudouridine(38-40)-synthase
MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRIHKRHVRIHPSSRTDRGVHAIQQYFHFDTDLNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRYDCVGKRYRYKVYQAQQRDPFQSGLKTFIPEPLDLDKMNRAAQQFIGTHDFTGFCSQKTEVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEVSDVPKLLESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSL
>CP029653.1|AWQ89223.1|2442150_2442957_-|cobalt-transport-family-protein
MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLTYLWMFALILFFMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITIETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMIMSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEELAVAMEVRGYDANVKRTSYRQLKWQLRDTLSLIMIIPIAIILFVLKYSGV
>CP029653.1|AWQ88470.1|2442946_2443807_-|energy-coupling-factor-transporter-ATP-binding-protein-EcfA-1
MIIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKEKLADWHIGLPEIVQLQYDFEQKHQTKLKDIALTEEAFVSLYKEWQHEK
>CP029653.1|AWQ88889.1|2443803_2444613_-|ABC-transporter-family-protein
MEDKNSVIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKDIGIVFQNPDNQFVGSIVKYDVAFGLENHAVPHDEMHRRVSEALEQVDMLERADYEPNALSGGQKQRVAIASVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKGTVYKEGTATEIFDHAEELTTIGLDLPFPIKINQMLGHQTSFLTYEGLVDQL
>CP029653.1|AWQ90075.1|2445014_2445803_-|integrase-core-domain-protein
MCRILGISRASYYKWVHYQSSELELENEQLKREIESIYHKYNGIYGYRRIYIYIRLKLGKQVNRKRIYRLMKELNLKAVIRQKRKPYRRSTPQITSENKLNRQFDIDTPNKVWLTDVTEFKIKEGSKIYLSAIYDLGAKRIVSYELGPSNNNQLVFKTFNQAIEKVENTKGILFHSDRGFQYTSKTFKHMLDECGMIQSMSRVSKCIDNGPMEGVWGTIKSEIFRGNKHFKFNSVEEATKTIHDFILFFNHERITLKMADSV
>CP029653.1|AWQ87763.1|2445826_2446555_-|helix-turn-helix-domain-protein
MSIKPKVDIDVLLYMFQEYEKGVSFQYLIDTLQLDINVNTLYPKYKYYKTHGIETLLTQKQYNHYSKELKLKVVNEYLNSNQSTQDIAIKYNIRSSTQVKNWIKMYTVGKEIKNQSPKTGVYIMKARKTTFEERVTIVEYYLNHKQSYREVAEHFNISYGQIYQWVHKYQAHGKNGLVDGRGKGKPKSMMTPEEQKEAEIQALKAQNRLLEMENDVLKKFQALEREMIQRENKSRHTKRSKR
>CP029653.1|AWQ87882.1|2446808_2447177_-|ribosomal-protein-L17
MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVVEKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTRILKQGPRRGDGAESVIIELV

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Crispr_ID: CP029653_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029653_12

2956952-2957035

Orphan

Consensus_repeat	Method
TTTCGAAATTCTCTGTGTTGGGACCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029653_12

>merge|CP029653|12|2956952-2957035|CRISPRCasFinder
TTTCGAAATTCTCTGTGTTGGGACCCACACCCTAACTCGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCC

>CP029653|12|11|2956952-2957035|CRISPRCasFinder
TTTCGAAATTCTCTGTGTTGGGACCC	ACACCCTAACTCGCATTGCCTGTAGAATTTCT
TTTCGAAATTCTCTGTGTTGGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
CP029653.1\|AWQ88038.1\|2951712_2952114_+\|integrase-core-domain-protein	unknown	unknown	gnl\|CDD\|225382
CP029653.1\|AWQ87992.1\|2958854_2960732_-\|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA	unknown	unknown	gnl\|CDD\|235362
CP029653.1\|AWQ89982.1\|2948931_2950812_+\|ftsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|376899
CP029653.1\|AWQ87716.1\|2955062_2955632_-\|helix-turn-helix-family-protein	unknown	unknown	gnl\|CDD\|238045
CP029653.1\|AWQ88624.1\|2952680_2953430_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373922
CP029653.1\|AWQ88941.1\|2953448_2954252_-\|subtilase-family-protein	unknown	unknown	gnl\|CDD\|173803
CP029653.1\|AWQ89425.1\|2958135_2958855_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-GidB	unknown	unknown	gnl\|CDD\|234637
CP029653.1\|AWQ88720.1\|2955884_2956280_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|288237
CP029653.1\|AWQ89792.1\|2954735_2954936_+\|cold-shock-protein-CspC	unknown	unknown	gnl\|CDD\|224197
CP029653.1\|AWQ87873.1\|2962321_2962669_-\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|234782
CP029653.1\|AWQ88137.1\|2950903_2951095_+\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ90086.1\|2956347_2956701_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|288237
CP029653.1\|AWQ88289.1\|2960798_2962178_-\|tRNA-modification-GTPase-TrmE	unknown	unknown	gnl\|CDD\|235392
CP029653.1\|AWQ87923.1\|2952181_2952679_-\|hypothetical-protein	unknown	unknown	unknown
CP029653.1\|AWQ88609.1\|2957253_2958093_-\|nucleoid-occlusion-protein	unknown	unknown	gnl\|CDD\|275105
CP029653.1\|AWQ88762.1\|2962795_2962933_-\|ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117

Protein	Function_ID	Function_description	E-value
CP029653.1\|AWQ88038.1\|2951712_2952114_+\|integrase-core-domain-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	3.26845e-33
CP029653.1\|AWQ87992.1\|2958854_2960732_-\|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
CP029653.1\|AWQ87716.1\|2955062_2955632_-\|helix-turn-helix-family-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.78153e-16
CP029653.1\|AWQ89982.1\|2948931_2950812_+\|ftsX-like-permease-family-protein	gnl\|CDD\|376899	pfam02687, FtsX, FtsX-like permease family. This is a family of predicted permeases and hypothetical transmembrane proteins. Buchnera aphidicola LolC has been shown to transport lipids targeted to the outer membrane across the inner membrane. Both LolC and Streptococcus cristatus TptD have been shown to require ATP. This region contains three transmembrane helices.	3.80447e-06
CP029653.1\|AWQ88624.1\|2952680_2953430_-\|hypothetical-protein	gnl\|CDD\|373922	pfam15526, Ntox21, Novel toxin 21. Bacterial genomes and plasmids encode a variety of peptide and protein toxins that mediate inter-bacterial competition. Bacteriocins are diffusible proteins that parasitize cell-envelope proteins to enter and kill bacteria. Contact-dependent growth inhibition (CDI) is one mechanism of inter-bacterial competition. Novel Toxin 21 (alternatively 16S rRNA endonuclease CdiA) belongs to a family of prokaryotic polymorphic toxin systems implicated in intra-specific conflicts. This RNase toxin found in bacterial polymorphic toxin systems, is proposed to adopt the BECR (Barnase-EndoU-ColicinE5/D-RelE) fold, with two conserved lysine residues and [DS]xDxxxH, RxG[ST] and RxxD motifs. In bacterial polymorphic toxin systems, the toxin is usually exported by the type 2, type 4, type 5 or type 7 secretion systems. This is also referred to as the E. cloacae CdiAC. The CdiAC proteins carry a variety of sequence-diverse C-terminal domains, which represent a collection of distinct toxins. Many CdiA-CT toxins have nuclease activities. In accord with the structural homology, CdiA-CT cleaves 16S rRNA at the same site as colicin E3 and this nuclease activity is responsible for growth inhibition.	4.66273e-23
CP029653.1\|AWQ88941.1\|2953448_2954252_-\|subtilase-family-protein	gnl\|CDD\|173803	cd07477, Peptidases_S8_Subtilisin_subset, Peptidase S8 family domain in Subtilisin proteins. This group is composed of many different subtilisins: Pro-TK-subtilisin, subtilisin Carlsberg, serine protease Pb92 subtilisin, and BPN subtilisins just to name a few. Pro-TK-subtilisin is a serine protease from the hyperthermophilic archaeon Thermococcus kodakaraensis and consists of a signal peptide, a propeptide, and a mature domain. TK-subtilisin is matured from pro-TK-subtilisin upon autoprocessing and degradation of the propeptide. Unlike other subtilisins though, the folding of the unprocessed form of pro-TK-subtilisin is induced by Ca2+ binding which is almost completed prior to autoprocessing. Ca2+ is required for activity unlike the bacterial subtilisins. The propeptide is not required for folding of the mature domain unlike the bacterial subtilases because of the stability produced from Ca2+ binding. Subtilisin Carlsberg is extremely similar in structure to subtilisin BPN'/Novo thought it has a 30% difference in amino acid sequence. The substrate binding regions are also similar and 2 possible Ca2+ binding sites have been identified recently. Subtilisin Carlsberg possesses the highest commercial importance as a proteolytic additive for detergents. Serine protease Pb92, the serine protease from the alkalophilic Bacillus strain PB92, also contains two calcium ions and the overall folding of the polypeptide chain closely resembles that of the subtilisins. Members of the peptidases S8 and S35 clan include endopeptidases, exopeptidases and also a tripeptidyl-peptidase. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The S53 family contains a catalytic triad Glu/Asp/Ser. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.02571e-48
CP029653.1\|AWQ89425.1\|2958135_2958855_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-GidB	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	3.53317e-96
CP029653.1\|AWQ88720.1\|2955884_2956280_-\|hypothetical-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	1.03254e-38
CP029653.1\|AWQ89792.1\|2954735_2954936_+\|cold-shock-protein-CspC	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	1.4289e-30
CP029653.1\|AWQ90086.1\|2956347_2956701_-\|hypothetical-protein	gnl\|CDD\|288237	pfam11345, DUF3147, Protein of unknown function (DUF3147). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	1.35852e-38
CP029653.1\|AWQ88289.1\|2960798_2962178_-\|tRNA-modification-GTPase-TrmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
CP029653.1\|AWQ87873.1\|2962321_2962669_-\|ribonuclease-P-protein-component	gnl\|CDD\|234782	PRK00499, rnpA, ribonuclease P; Reviewed.	6.56083e-51
CP029653.1\|AWQ88609.1\|2957253_2958093_-\|nucleoid-occlusion-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	1.78633e-112
CP029653.1\|AWQ88762.1\|2962795_2962933_-\|ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	8.39798e-10

>CP029653.1|AWQ90086.1|2956347_2956701_-|hypothetical-protein
MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFLAAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLTSLYIKHKGYRKGAIFTVVCWFVISLAIFSIRHL
>CP029653.1|AWQ88720.1|2955884_2956280_-|hypothetical-protein
MKLTLMKFFVGGFAVLLSYIVSVTLPWKEFGGIFATFPAVFLVSMFITGMQYGDKVAVHVNRGAVFGMTGVLVCILVTWMMLHMTHMWLISIIVGFLSWFISAVCIFEAVEFIAQKRLEKHSWKAGKSNSK
>CP029653.1|AWQ87716.1|2955062_2955632_-|helix-turn-helix-family-protein
MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDIHNLLMMCDLFNVTLDDLVKGTIPFAPDIKAQRSLNLWTYVMLIFMTLAAILTGPLVVYWNWAWGITVIVIYGIGYYASMKIEDFKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNIKTGVLSFIAFVGAIILIALISMHLANKFL
>CP029653.1|AWQ89792.1|2954735_2954936_+|cold-shock-protein-CspC
MNNGTVKWFNAEKGFGFIEQENGGDVFVHFSGIASDGYKTLEEGQKVTFEITEGQRGDQAVNVQTV
>CP029653.1|AWQ88941.1|2953448_2954252_-|subtilase-family-protein
MSRNLIHLSIGVAIFIISFSFYLLNQPNNWAWSSLNICINDSKPSNVKVAILDTGINNTRINNNFVTKRYNAINNHNQITTDSNHATQVASIITYGEHKEKLIGISKSVSIYDVKVLDDNLKGDIDNIIKGITWSIKNDVNIIHMSFGFQRYNKELHDAIKNAKNKGIILVAAAGNNMDDYSDYPARFNEVYSITAIDKNNKPFIYAPTKKIDFKAPGVDVYTKGSKDELLTVNGTSFAAAYFTAYLTNNLEFRNDLPHILKEYPIK
>CP029653.1|AWQ88624.1|2952680_2953430_-|hypothetical-protein
MKNKIIILFLAIIITFTYGNFAEASVVIKEANINNSNSKINTNKINENIYSKNNRNYIDNNFKSKDLNIESSLGHDLNTDKITVDASLKDNYNNKLDKTYDVKFLRIVNENDFKAEFTDQDTGEKIIYDTNEVKASIAPVVAVLVGFIAKQGLKKAIQKYGKTVVTSMIRTSPQVAAQAAKKLGYSATKHVSHGKKVFKKNSKGRPQYISVDKDGHRGGAWKGASSIKNLGSKKTRSGTYDANLKRIGD
>CP029653.1|AWQ87923.1|2952181_2952679_-|hypothetical-protein
MIINLETQQIHFDLEHEIPYFQSPEKNRIRLDIDVLNKKQISNIINVIFNNQSKTKCTFLSEYLYPVKFREKTRIGRFFNITNWYEEIHSADEKYVIATIKNIKNKDLIDYSLYIKKGLVEPFIVFYNQENIFYISNAVIDIISVSKDTLGYIKSEFNDHCASPY
>CP029653.1|AWQ88038.1|2951712_2952114_+|integrase-core-domain-protein
MIITLRSLGRKATDIENALNSMFSALPSHIFKSITFDCGKEFSNWKTICNCHDISIFFADPSMPAQRGLNEHSNGILRRSGLDKELDFNLVTDDHIISVAQKINHRPRKSLGYRTPLEVFMSFIKDDKLSSLI
>CP029653.1|AWQ88137.1|2950903_2951095_+|hypothetical-protein
MKFRELVKQSYEDLKNLTVTWYNVIALAIIVIVLSTVTTPIIGIPAGLLGGAYYLKRREEKGK
>CP029653.1|AWQ89982.1|2948931_2950812_+|ftsX-like-permease-family-protein
MTFNHIVLKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGVNNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRCTREFALFQLIGLTRQNILKMLALEQMIVFIITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTILMLIIAYILILFQSSLFLKRRSILSMMKDSVKTDVTTAKVTVIEVISGVLGIAMIALGYYMATEMFGTFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVVFTSSIMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLTSMAPNDFNVVASQDAQQFESKLSQQHITFSKNYYETITVDNVKDQVITLENGSDSGRTNSILSANTKLTGNNAIITNTKSLPNVINIHLNNDLVVKGTKNETFRVTQEDKDKVYPLNLSFNSPVIEVSPEKYQQLKTQNNVHTFYGYDIKQTSQKKKAQAIAKQFGDKIITYDDMKKEVDATNGILIFVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNFGLPLLIAILHAVFAAIAFMKLMGNISFMPVIIVIIVYTLIYIVFALIAFVHSNKLIKKTI
>CP029653.1|AWQ88609.1|2957253_2958093_-|nucleoid-occlusion-protein
MKKPFSKLFGLKNKDDIIGHIEENRNSNVESIQIERIVPNRYQPRQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVIIRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIANKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRVRQKTGPEKVKAQNLRFEQDVTQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRIYKR
>CP029653.1|AWQ89425.1|2958135_2958855_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-GidB
MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSITDEHDVYLKHFYDSIAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSLNKRIQFLNYLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLPLVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKRQTPKKYPRKPGTPNKTPLLEK
>CP029653.1|AWQ87992.1|2958854_2960732_-|tRNA-uridine-5-carboxymethylaminomethyl-modification-enzyme-GidA
MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMPCNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGEIILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPGDDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPSIEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMMRAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKVLNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGYELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAIDLLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKIPEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVSD
>CP029653.1|AWQ88289.1|2960798_2962178_-|tRNA-modification-GTPase-TrmE
MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADKLYKGKHLLNDVPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELTMTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLIKKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIMREGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDTAGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIVNKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYVSNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQLFSQFCLGK
>CP029653.1|AWQ87873.1|2962321_2962669_-|ribonuclease-P-protein-component
MEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFRLGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSLEHVLKIAKVFNKKIK
>CP029653.1|AWQ88762.1|2962795_2962933_-|ribosomal-protein-L34
MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLSA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP029653_5	5.1\|844552\|33\|CP029653\|CRISPRCasFinder	844552-844584	33	CP029653.1	1101812-1101844	1	0.97
CP029653_5	5.1\|844552\|33\|CP029653\|CRISPRCasFinder	844552-844584	33	CP029653.1	2316230-2316262	1	0.97
CP029653_5	5.1\|844552\|33\|CP029653\|CRISPRCasFinder	844552-844584	33	CP029653.1	2513730-2513762	1	0.97
CP029653_9	9.2\|2128240\|36\|CP029653\|CRT	2128240-2128275	36	CP029653.1	2128126-2128161	1	0.972
CP029653_12	12.1\|2956978\|32\|CP029653\|CRISPRCasFinder	2956978-2957009	32	CP029653.1	2513699-2513730	1	0.969
CP029653_6	6.1\|974666\|26\|CP029653\|CRISPRCasFinder	974666-974691	26	CP029653.1	2255928-2255953	2	0.923
CP029653_6	6.1\|974666\|26\|CP029653\|CRISPRCasFinder	974666-974691	26	CP029653.1	2316008-2316033	2	0.923
CP029653_9	9.2\|2128240\|36\|CP029653\|CRT	2128240-2128275	36	CP029653.1	323494-323529	2	0.944
CP029653_9	9.2\|2128240\|36\|CP029653\|CRT	2128240-2128275	36	CP029653.1	404141-404176	2	0.944
CP029653_9	9.2\|2128240\|36\|CP029653\|CRT	2128240-2128275	36	CP029653.1	553354-553389	2	0.944
CP029653_9	9.2\|2128240\|36\|CP029653\|CRT	2128240-2128275	36	CP029653.1	809473-809508	2	0.944
CP029653_9	9.2\|2128240\|36\|CP029653\|CRT	2128240-2128275	36	CP029653.1	844591-844626	2	0.944
CP029653_9	9.2\|2128240\|36\|CP029653\|CRT	2128240-2128275	36	CP029653.1	1911756-1911791	2	0.944
CP029653_9	9.2\|2128240\|36\|CP029653\|CRT	2128240-2128275	36	CP029653.1	2478301-2478336	2	0.944
CP029653_9	9.2\|2128240\|36\|CP029653\|CRT	2128240-2128275	36	CP029653.1	2619561-2619596	2	0.944
CP029653_9	9.4\|2128353\|36\|CP029653\|CRT	2128353-2128388	36	CP029653.1	323495-323530	2	0.944
CP029653_9	9.4\|2128353\|36\|CP029653\|CRT	2128353-2128388	36	CP029653.1	404142-404177	2	0.944
CP029653_9	9.4\|2128353\|36\|CP029653\|CRT	2128353-2128388	36	CP029653.1	553355-553390	2	0.944
CP029653_9	9.4\|2128353\|36\|CP029653\|CRT	2128353-2128388	36	CP029653.1	809474-809509	2	0.944
CP029653_9	9.4\|2128353\|36\|CP029653\|CRT	2128353-2128388	36	CP029653.1	844590-844625	2	0.944
CP029653_9	9.4\|2128353\|36\|CP029653\|CRT	2128353-2128388	36	CP029653.1	1911757-1911792	2	0.944
CP029653_9	9.4\|2128353\|36\|CP029653\|CRT	2128353-2128388	36	CP029653.1	2478300-2478335	2	0.944
CP029653_9	9.4\|2128353\|36\|CP029653\|CRT	2128353-2128388	36	CP029653.1	2619562-2619597	2	0.944
CP029653_12	12.1\|2956978\|32\|CP029653\|CRISPRCasFinder	2956978-2957009	32	CP029653.1	844584-844615	2	0.938
CP029653_12	12.1\|2956978\|32\|CP029653\|CRISPRCasFinder	2956978-2957009	32	CP029653.1	1101902-1101933	2	0.938
CP029653_12	12.1\|2956978\|32\|CP029653\|CRISPRCasFinder	2956978-2957009	32	CP029653.1	2002142-2002173	2	0.938

1. spacer 5.1|844552|33|CP029653|CRISPRCasFinder matches to position: 1101812-1101844, mismatch: 1, identity: 0.97

attgggaatccaatttctctttgttggggccca	CRISPR spacer
attgggaatccaatttctctgtgttggggccca	Protospacer
******************** ************

2. spacer 5.1|844552|33|CP029653|CRISPRCasFinder matches to position: 2316230-2316262, mismatch: 1, identity: 0.97

attgggaatccaatttctctttgttggggccca	CRISPR spacer
attgggaatacaatttctctttgttggggccca	Protospacer
********* ***********************

3. spacer 5.1|844552|33|CP029653|CRISPRCasFinder matches to position: 2513730-2513762, mismatch: 1, identity: 0.97

attgggaatccaatttctctttgttggggccca	CRISPR spacer
attgggaatccaatttctctttgttgggaccca	Protospacer
****************************.****

4. spacer 9.2|2128240|36|CP029653|CRT matches to position: 2128126-2128161, mismatch: 1, identity: 0.972

aacttgcattgtctgtagaatttcttttcaaaattc	CRISPR spacer
aacttacattgtctgtagaatttcttttcaaaattc	Protospacer
*****.******************************

5. spacer 12.1|2956978|32|CP029653|CRISPRCasFinder matches to position: 2513699-2513730, mismatch: 1, identity: 0.969

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaactcgcattgcctgtagaatttct	Protospacer
******.*************************

6. spacer 6.1|974666|26|CP029653|CRISPRCasFinder matches to position: 2255928-2255953, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggtgg	CRISPR spacer
cgcggccccaacacagaagctggcgg	Protospacer
** ********************.**

7. spacer 6.1|974666|26|CP029653|CRISPRCasFinder matches to position: 2316008-2316033, mismatch: 2, identity: 0.923

cggggccccaacacagaagctggtgg	CRISPR spacer
cggggccccaacacaaaagctggcgg	Protospacer
***************.*******.**

8. spacer 9.2|2128240|36|CP029653|CRT matches to position: 323494-323529, mismatch: 2, identity: 0.944

aacttgcattgtctgtagaatttcttttcaaaattc	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
***********.*****************.******

9. spacer 9.2|2128240|36|CP029653|CRT matches to position: 404141-404176, mismatch: 2, identity: 0.944

aacttgcattgtctgtagaatttcttttcaaaattc	CRISPR spacer
aacttgcattgtttgtagaatttcttttcgaaattc	Protospacer
************.****************.******

10. spacer 9.2|2128240|36|CP029653|CRT matches to position: 553354-553389, mismatch: 2, identity: 0.944

aacttgcattgtctgtagaatttcttttcaaaattc	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
***********.*****************.******

11. spacer 9.2|2128240|36|CP029653|CRT matches to position: 809473-809508, mismatch: 2, identity: 0.944

aacttgcattgtctgtagaatttcttttcaaaattc	CRISPR spacer
aacttgcattgtttgtagaatttcttttcgaaattc	Protospacer
************.****************.******

12. spacer 9.2|2128240|36|CP029653|CRT matches to position: 844591-844626, mismatch: 2, identity: 0.944

aacttgcattgtctgtagaatttcttttcaaaattc	CRISPR spacer
aacttgcattgcctgtagaatttcttttcgaaattc	Protospacer
***********.*****************.******

13. spacer 9.2|2128240|36|CP029653|CRT matches to position: 1911756-1911791, mismatch: 2, identity: 0.944

aacttgcattgtctgtagaatttcttttcaaaattc	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaattc	Protospacer
****************************..******

14. spacer 9.2|2128240|36|CP029653|CRT matches to position: 2478301-2478336, mismatch: 2, identity: 0.944

aacttgcattgtctgtagaatttcttttcaaaattc	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaattc	Protospacer
****************************..******

15. spacer 9.2|2128240|36|CP029653|CRT matches to position: 2619561-2619596, mismatch: 2, identity: 0.944

aacttgcattgtctgtagaatttcttttcaaaattc	CRISPR spacer
aacttgcattgtctgtagaatttctttttgaaattc	Protospacer
****************************..******

16. spacer 9.4|2128353|36|CP029653|CRT matches to position: 323495-323530, mismatch: 2, identity: 0.944

caacttgcattgtctgtagaatttcctttcgaaatt	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaatt	Protospacer
************.************.**********

17. spacer 9.4|2128353|36|CP029653|CRT matches to position: 404142-404177, mismatch: 2, identity: 0.944

caacttgcattgtctgtagaatttcctttcgaaatt	CRISPR spacer
caacttgcattgtttgtagaatttcttttcgaaatt	Protospacer
*************.***********.**********

18. spacer 9.4|2128353|36|CP029653|CRT matches to position: 553355-553390, mismatch: 2, identity: 0.944

caacttgcattgtctgtagaatttcctttcgaaatt	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaatt	Protospacer
************.************.**********

19. spacer 9.4|2128353|36|CP029653|CRT matches to position: 809474-809509, mismatch: 2, identity: 0.944

caacttgcattgtctgtagaatttcctttcgaaatt	CRISPR spacer
caacttgcattgtttgtagaatttcttttcgaaatt	Protospacer
*************.***********.**********

20. spacer 9.4|2128353|36|CP029653|CRT matches to position: 844590-844625, mismatch: 2, identity: 0.944

caacttgcattgtctgtagaatttcctttcgaaatt	CRISPR spacer
caacttgcattgcctgtagaatttcttttcgaaatt	Protospacer
************.************.**********

21. spacer 9.4|2128353|36|CP029653|CRT matches to position: 1911757-1911792, mismatch: 2, identity: 0.944

caacttgcattgtctgtagaatttcctttcgaaatt	CRISPR spacer
caacttgcattgtctgtagaatttctttttgaaatt	Protospacer
*************************.***.******

22. spacer 9.4|2128353|36|CP029653|CRT matches to position: 2478300-2478335, mismatch: 2, identity: 0.944

caacttgcattgtctgtagaatttcctttcgaaatt	CRISPR spacer
caacttgcattgtctgtagaatttctttttgaaatt	Protospacer
*************************.***.******

23. spacer 9.4|2128353|36|CP029653|CRT matches to position: 2619562-2619597, mismatch: 2, identity: 0.944

caacttgcattgtctgtagaatttcctttcgaaatt	CRISPR spacer
caacttgcattgtctgtagaatttctttttgaaatt	Protospacer
*************************.***.******

24. spacer 12.1|2956978|32|CP029653|CRISPRCasFinder matches to position: 844584-844615, mismatch: 2, identity: 0.938

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaacttgcattgcctgtagaatttct	Protospacer
******.****.********************

25. spacer 12.1|2956978|32|CP029653|CRISPRCasFinder matches to position: 1101902-1101933, mismatch: 2, identity: 0.938

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaacttgcattgcctgtagaatttct	Protospacer
******.****.********************

26. spacer 12.1|2956978|32|CP029653|CRISPRCasFinder matches to position: 2002142-2002173, mismatch: 2, identity: 0.938

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaacgcgcattgcctgtagaatttct	Protospacer
******.*** *********************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP029653_1	1.11\|62029\|34\|CP029653\|PILER-CR	62029-62062	34	NC_013373	Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence	26794-26827	2	0.941
CP029653_1	1.21\|61960\|34\|CP029653\|CRISPRCasFinder	61960-61993	34	MK936475	Staphylococcus phage SA03-CTH2, complete genome	14281-14314	2	0.941
CP029653_1	1.21\|61960\|34\|CP029653\|CRISPRCasFinder	61960-61993	34	MT926124	Staphylococcus phage vB_SauP_EBHT, complete genome	2846-2879	2	0.941
CP029653_1	1.21\|61960\|34\|CP029653\|CRISPRCasFinder	61960-61993	34	MK922548	Staphylococcus phage SA46-CTH4, complete genome	3204-3237	2	0.941
CP029653_1	1.21\|61960\|34\|CP029653\|CRISPRCasFinder	61960-61993	34	MK922547	Staphylococcus phage SA30-CTH2, complete genome	3197-3230	2	0.941
CP029653_1	1.21\|61960\|34\|CP029653\|CRISPRCasFinder	61960-61993	34	KJ210330	Staphylococcus phage GRCS, complete genome	3491-3524	2	0.941
CP029653_1	1.22\|62031\|32\|CP029653\|CRISPRCasFinder	62031-62062	32	NC_013373	Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence	26794-26825	2	0.938
CP029653_1	1.33\|61959\|35\|CP029653\|CRT	61959-61993	35	MT926124	Staphylococcus phage vB_SauP_EBHT, complete genome	2846-2880	2	0.943
CP029653_1	1.33\|61959\|35\|CP029653\|CRT	61959-61993	35	MK922548	Staphylococcus phage SA46-CTH4, complete genome	3204-3238	2	0.943
CP029653_1	1.33\|61959\|35\|CP029653\|CRT	61959-61993	35	MK922547	Staphylococcus phage SA30-CTH2, complete genome	3197-3231	2	0.943
CP029653_1	1.33\|61959\|35\|CP029653\|CRT	61959-61993	35	KJ210330	Staphylococcus phage GRCS, complete genome	3491-3525	2	0.943
CP029653_1	1.33\|61959\|35\|CP029653\|CRT	61959-61993	35	MK936475	Staphylococcus phage SA03-CTH2, complete genome	14280-14314	2	0.943
CP029653_1	1.34\|62030\|33\|CP029653\|CRT	62030-62062	33	NC_013373	Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence	26794-26826	2	0.939
CP029653_1	1.10\|61958\|36\|CP029653\|PILER-CR	61958-61993	36	MK936475	Staphylococcus phage SA03-CTH2, complete genome	14279-14314	3	0.917
CP029653_1	1.10\|61958\|36\|CP029653\|PILER-CR	61958-61993	36	MT926124	Staphylococcus phage vB_SauP_EBHT, complete genome	2846-2881	3	0.917
CP029653_1	1.10\|61958\|36\|CP029653\|PILER-CR	61958-61993	36	MK922548	Staphylococcus phage SA46-CTH4, complete genome	3204-3239	3	0.917
CP029653_1	1.10\|61958\|36\|CP029653\|PILER-CR	61958-61993	36	MK922547	Staphylococcus phage SA30-CTH2, complete genome	3197-3232	3	0.917
CP029653_1	1.10\|61958\|36\|CP029653\|PILER-CR	61958-61993	36	KJ210330	Staphylococcus phage GRCS, complete genome	3491-3526	3	0.917
CP029653_1	1.23\|62100\|34\|CP029653\|CRISPRCasFinder	62100-62133	34	NZ_CP043848	Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence	50879-50912	6	0.824
CP029653_1	1.35\|62099\|35\|CP029653\|CRT	62099-62133	35	NZ_CP043848	Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence	50879-50913	6	0.829
CP029653_2	2.2\|70997\|41\|CP029653\|CRISPRCasFinder	70997-71037	41	MF417907	Uncultured Caudovirales phage clone 7F_7, partial genome	31442-31482	6	0.854
CP029653_2	2.2\|70997\|41\|CP029653\|CRISPRCasFinder	70997-71037	41	KY653129	Staphylococcus phage IME1365_01, complete genome	11951-11991	6	0.854
CP029653_2	2.5\|70996\|42\|CP029653\|CRT	70996-71037	42	KY653129	Staphylococcus phage IME1365_01, complete genome	11951-11992	7	0.833
CP029653_2	2.5\|70996\|42\|CP029653\|CRT	70996-71037	42	MF417907	Uncultured Caudovirales phage clone 7F_7, partial genome	31441-31482	7	0.833
CP029653_8	8.1\|2117505\|35\|CP029653\|CRISPRCasFinder	2117505-2117539	35	NZ_CP009619	Vibrio coralliilyticus strain RE98 plasmid p380, complete sequence	270871-270905	7	0.8
CP029653_1	1.21\|61960\|34\|CP029653\|CRISPRCasFinder	61960-61993	34	KR131711	Fusobacterium phage Funu2 supercont1.1, partial genome	26442-26475	8	0.765
CP029653_3	3.1\|690183\|29\|CP029653\|CRISPRCasFinder	690183-690211	29	NZ_CP026273	Klebsiella oxytoca strain KONIH4 plasmid pKOX-ea2b, complete sequence	142439-142467	8	0.724
CP029653_1	1.19\|61816\|35\|CP029653\|CRISPRCasFinder	61816-61850	35	AP014336	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S36-C72, * SEQUENCING IN PROGRESS *	7580-7614	9	0.743
CP029653_1	1.19\|61816\|35\|CP029653\|CRISPRCasFinder	61816-61850	35	AP013668	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C107A-MedDCM-OCT-S23-C39, * SEQUENCING IN PROGRESS *	12965-12999	9	0.743
CP029653_1	1.19\|61816\|35\|CP029653\|CRISPRCasFinder	61816-61850	35	AP013410	Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C107A-MedDCM-OCT-S27-C42	17610-17644	9	0.743

1. spacer 1.11|62029|34|CP029653|PILER-CR matches to NC_013373 (Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence) position: , mismatch: 2, identity: 0.941

ctcatctttcatgtcactgattaattcatttgta	CRISPR spacer
ctcatctttcatatcattgattaattcatttgta	Protospacer
************.***.*****************

2. spacer 1.21|61960|34|CP029653|CRISPRCasFinder matches to MK936475 (Staphylococcus phage SA03-CTH2, complete genome) position: , mismatch: 2, identity: 0.941

agttaacggcattacctaataaaaatattttagg	CRISPR spacer
agttaacagcattacctaataagaatattttagg	Protospacer
*******.**************.***********

3. spacer 1.21|61960|34|CP029653|CRISPRCasFinder matches to MT926124 (Staphylococcus phage vB_SauP_EBHT, complete genome) position: , mismatch: 2, identity: 0.941

agttaacggcattacctaataaaaatattttagg	CRISPR spacer
agttaacagcattacctaataaaaatatttttgg	Protospacer
*******.*********************** **

4. spacer 1.21|61960|34|CP029653|CRISPRCasFinder matches to MK922548 (Staphylococcus phage SA46-CTH4, complete genome) position: , mismatch: 2, identity: 0.941

agttaacggcattacctaataaaaatattttagg	CRISPR spacer
agttaacagcattacctaataagaatattttagg	Protospacer
*******.**************.***********

5. spacer 1.21|61960|34|CP029653|CRISPRCasFinder matches to MK922547 (Staphylococcus phage SA30-CTH2, complete genome) position: , mismatch: 2, identity: 0.941

agttaacggcattacctaataaaaatattttagg	CRISPR spacer
agttaacagcattacctaataagaatattttagg	Protospacer
*******.**************.***********

6. spacer 1.21|61960|34|CP029653|CRISPRCasFinder matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 2, identity: 0.941

agttaacggcattacctaataaaaatattttagg	CRISPR spacer
agttaacagcattacctaataaaaatatttttgg	Protospacer
*******.*********************** **

7. spacer 1.22|62031|32|CP029653|CRISPRCasFinder matches to NC_013373 (Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence) position: , mismatch: 2, identity: 0.938

catctttcatgtcactgattaattcatttgta	CRISPR spacer
catctttcatatcattgattaattcatttgta	Protospacer
**********.***.*****************

8. spacer 1.33|61959|35|CP029653|CRT matches to MT926124 (Staphylococcus phage vB_SauP_EBHT, complete genome) position: , mismatch: 2, identity: 0.943

aagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aagttaacagcattacctaataaaaatatttttgg	Protospacer
********.*********************** **

9. spacer 1.33|61959|35|CP029653|CRT matches to MK922548 (Staphylococcus phage SA46-CTH4, complete genome) position: , mismatch: 2, identity: 0.943

aagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aagttaacagcattacctaataagaatattttagg	Protospacer
********.**************.***********

10. spacer 1.33|61959|35|CP029653|CRT matches to MK922547 (Staphylococcus phage SA30-CTH2, complete genome) position: , mismatch: 2, identity: 0.943

aagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aagttaacagcattacctaataagaatattttagg	Protospacer
********.**************.***********

11. spacer 1.33|61959|35|CP029653|CRT matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 2, identity: 0.943

aagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aagttaacagcattacctaataaaaatatttttgg	Protospacer
********.*********************** **

12. spacer 1.33|61959|35|CP029653|CRT matches to MK936475 (Staphylococcus phage SA03-CTH2, complete genome) position: , mismatch: 2, identity: 0.943

aagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aagttaacagcattacctaataagaatattttagg	Protospacer
********.**************.***********

13. spacer 1.34|62030|33|CP029653|CRT matches to NC_013373 (Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence) position: , mismatch: 2, identity: 0.939

tcatctttcatgtcactgattaattcatttgta	CRISPR spacer
tcatctttcatatcattgattaattcatttgta	Protospacer
***********.***.*****************

14. spacer 1.10|61958|36|CP029653|PILER-CR matches to MK936475 (Staphylococcus phage SA03-CTH2, complete genome) position: , mismatch: 3, identity: 0.917

taagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aaagttaacagcattacctaataagaatattttagg	Protospacer
 ********.**************.***********

15. spacer 1.10|61958|36|CP029653|PILER-CR matches to MT926124 (Staphylococcus phage vB_SauP_EBHT, complete genome) position: , mismatch: 3, identity: 0.917

taagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aaagttaacagcattacctaataaaaatatttttgg	Protospacer
 ********.*********************** **

16. spacer 1.10|61958|36|CP029653|PILER-CR matches to MK922548 (Staphylococcus phage SA46-CTH4, complete genome) position: , mismatch: 3, identity: 0.917

taagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aaagttaacagcattacctaataagaatattttagg	Protospacer
 ********.**************.***********

17. spacer 1.10|61958|36|CP029653|PILER-CR matches to MK922547 (Staphylococcus phage SA30-CTH2, complete genome) position: , mismatch: 3, identity: 0.917

taagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aaagttaacagcattacctaataagaatattttagg	Protospacer
 ********.**************.***********

18. spacer 1.10|61958|36|CP029653|PILER-CR matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 3, identity: 0.917

taagttaacggcattacctaataaaaatattttagg	CRISPR spacer
aaagttaacagcattacctaataaaaatatttttgg	Protospacer
 ********.*********************** **

19. spacer 1.23|62100|34|CP029653|CRISPRCasFinder matches to NZ_CP043848 (Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.824

gtaatagttgctcaataggtaataaaacgtcggt	CRISPR spacer
ggaatagttgctcgataggtaataaaacgtttac	Protospacer
* ***********.****************. ..

20. spacer 1.35|62099|35|CP029653|CRT matches to NZ_CP043848 (Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.829

ggtaatagttgctcaataggtaataaaacgtcggt	CRISPR spacer
gggaatagttgctcgataggtaataaaacgtttac	Protospacer
** ***********.****************. ..

21. spacer 2.2|70997|41|CP029653|CRISPRCasFinder matches to MF417907 (Uncultured Caudovirales phage clone 7F_7, partial genome) position: , mismatch: 6, identity: 0.854

aactgatatactcctttaccatgtattaattctggaccact	CRISPR spacer
tattcatatactcccttgccatgtattaattctggaccacg	Protospacer
 *.* *********.**.**********************

22. spacer 2.2|70997|41|CP029653|CRISPRCasFinder matches to KY653129 (Staphylococcus phage IME1365_01, complete genome) position: , mismatch: 6, identity: 0.854

aactgatatactcctttaccatgtattaattctggaccact	CRISPR spacer
tattcataaactcctttgccatgtattaattctggaccacg	Protospacer
 *.* *** ********.**********************

23. spacer 2.5|70996|42|CP029653|CRT matches to KY653129 (Staphylococcus phage IME1365_01, complete genome) position: , mismatch: 7, identity: 0.833

gaactgatatactcctttaccatgtattaattctggaccact	CRISPR spacer
atattcataaactcctttgccatgtattaattctggaccacg	Protospacer
. *.* *** ********.**********************

24. spacer 2.5|70996|42|CP029653|CRT matches to MF417907 (Uncultured Caudovirales phage clone 7F_7, partial genome) position: , mismatch: 7, identity: 0.833

gaactgatatactcctttaccatgtattaattctggaccact	CRISPR spacer
atattcatatactcccttgccatgtattaattctggaccacg	Protospacer
. *.* *********.**.**********************

25. spacer 8.1|2117505|35|CP029653|CRISPRCasFinder matches to NZ_CP009619 (Vibrio coralliilyticus strain RE98 plasmid p380, complete sequence) position: , mismatch: 7, identity: 0.8

ctgcattgcctgtagaatttcttttttcgaaattc	CRISPR spacer
ctgcattacctgtagcatttcttttttcaactacc	Protospacer
*******.******* ************.*   .*

26. spacer 1.21|61960|34|CP029653|CRISPRCasFinder matches to KR131711 (Fusobacterium phage Funu2 supercont1.1, partial genome) position: , mismatch: 8, identity: 0.765

agttaacggcattacctaataaaaatattttagg	CRISPR spacer
aattaactgcattatctaataaaaatggttactg	Protospacer
*.***** ******.***********. **   *

27. spacer 3.1|690183|29|CP029653|CRISPRCasFinder matches to NZ_CP026273 (Klebsiella oxytoca strain KONIH4 plasmid pKOX-ea2b, complete sequence) position: , mismatch: 8, identity: 0.724

ccgcacaactgcataaatccctctaatcg	CRISPR spacer
attcacaactatataaatccctctaaatt	Protospacer
 . *******..************** .

28. spacer 1.19|61816|35|CP029653|CRISPRCasFinder matches to AP014336 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S36-C72, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.743

caacttcgtcatctttcatcatttctcttacatca	CRISPR spacer
agtatcggggatctttcatcatttgtcttacatca	Protospacer
 .  *. *  ************** **********

29. spacer 1.19|61816|35|CP029653|CRISPRCasFinder matches to AP013668 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C107A-MedDCM-OCT-S23-C39, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 9, identity: 0.743

caacttcgtcatctttcatcatttctcttacatca	CRISPR spacer
aatatcttttatcattcatcatttcttttacatca	Protospacer
 *  *.. *.*** ************.********

30. spacer 1.19|61816|35|CP029653|CRISPRCasFinder matches to AP013410 (Uncultured Mediterranean phage uvMED DNA, complete genome, group G16, isolate: uvMED-CGR-C107A-MedDCM-OCT-S27-C42) position: , mismatch: 9, identity: 0.743

caacttcgtcatctttcatcatttctcttacatca	CRISPR spacer
aatatcttttatcattcatcatttcttttacatca	Protospacer
 *  *.. *.*** ************.********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

787856 : 795676

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ88400.1\|787856_788912_-	histidine protein kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
AWQ88813.1\|788911_789598_-	response regulator	NA	NA	NA	NA
AWQ88106.1\|789572_790046_-	doxX family protein	NA	NA	NA	NA
AWQ88607.1\|790387_790828_-	electron transfer DM13 family protein	NA	NA	NA	NA
AWQ88293.1\|791107_791692_-	putative membrane protein	NA	NA	NA	NA
AWQ89289.1\|791790_792504_-	7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AWQ87547.1\|792507_792927_-	queuosine biosynthesis protein QueD	S4U060	uncultured_phage	6.3e-07	28.7
AWQ87539.1\|792928_793597_-	queuosine biosynthesis protein QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AWQ89524.1\|793947_794541_+	glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein	A0A0P0IKJ1	Acinetobacter_phage	6.8e-39	44.0
AWQ89341.1\|794524_795676_+	chorismate binding enzyme family protein	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_2

807648 : 821786

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ88749.1\|807648_808707_+	histidinol-phosphate transaminase	A0A0H3TLT9	Faustovirus	5.7e-20	26.5
AWQ89273.1\|808865_809408_+	putative 5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AWQ89470.1\|809959_810877_-	putative lipid kinase	A0A1V0SBJ0	Catovirus	8.2e-07	22.0
AWQ89771.1\|811146_812652_-	H+ symporter family protein	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AWQ88723.1\|812991_813492_-	7-cyano-7-deazaguanine reductase	E7DN65	Pneumococcus_phage	2.7e-52	66.2
AWQ87903.1\|813511_814378_-	eamA-like transporter family protein	NA	NA	NA	NA
AWQ87529.1\|815179_815578_+	nrdI protein	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AWQ87450.1\|815540_817646_+	ribonucleoside-diphosphate reductase, alpha subunit	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.6
AWQ87830.1\|817765_818737_+	ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AWQ88942.1\|819113_820085_+	fecCD transport family protein	A0A2H4IY97	uncultured_Caudovirales_phage	7.8e-141	80.2
AWQ88210.1\|820071_821028_+	fecCD transport family protein	A0A2H4J116	uncultured_Caudovirales_phage	5.5e-06	60.0
AWQ87574.1\|821024_821786_+	ABC transporter family protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	7.2e-17	30.1

DBSCAN-SWA_3

838075 : 902522

Staphylococcus_phage(42.42%)

coat,integrase,terminase,transposase

attL 839926:839942|attR 895205:895221

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ89504.1\|838075_839746_-\|transposase	transposase DDE domain protein	A0ZS58	Staphylococcus_virus	5.5e-243	77.4
839926:839942	attL	NA	NA	NA	NA
AWQ87630.1\|840393_842925_+	preprotein translocase, SecA subunit	NA	NA	NA	NA
AWQ88150.1\|843357_844350_+	peptide chain release factor 2	NA	NA	NA	NA
AWQ89439.1\|845118_845958_+	staphyloxanthin biosynthesis protein, putative	A0A2H4J675	uncultured_Caudovirales_phage	3.5e-12	42.2
AWQ89403.1\|846131_846782_+	HD containing hydrolase-like enzyme family protein	NA	NA	NA	NA
AWQ89031.1\|846778_847015_+	hypothetical protein	NA	NA	NA	NA
AWQ88741.1\|847283_849269_+	excinuclease ABC subunit B	NA	NA	NA	NA
AWQ89476.1\|849276_852123_+	excinuclease ABC subunit A	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	57.2
AWQ88487.1\|852733_853666_+	HPr(Ser) kinase/phosphatase	NA	NA	NA	NA
AWQ89331.1\|853671_854514_+	prolipoprotein diacylglyceryl transferase	NA	NA	NA	NA
AWQ88141.1\|854521_855007_+	bacterial transferase hexapeptide family protein	NA	NA	NA	NA
AWQ89964.1\|855014_856454_+	TPR repeat family protein	NA	NA	NA	NA
AWQ89452.1\|856520_857456_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.9e-84	49.2
AWQ88960.1\|858107_859019_+	hypothetical protein	A0A0R8VB27	Thermobifida_phage	1.1e-08	36.1
AWQ88847.1\|859015_860011_+	hypothetical protein	A1IMD5	Streptococcus_phage	4.8e-53	41.9
AWQ89337.1\|860119_861064_+	sporulation Regulator WhiA C terminal domain protein	Q7AWZ3	Streptococcus_phage	2.4e-54	40.6
AWQ88676.1\|861122_862070_-\|integrase	integrase core domain protein	Q9MBM9	Staphylococcus_prophage	1.1e-184	100.0
AWQ87975.1\|862706_863294_+	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	8.2e-53	55.3
AWQ87961.1\|863475_865110_+	malic enzyme, NAD binding domain protein	NA	NA	NA	NA
AWQ88153.1\|865316_866219_-	NAD dependent epimerase/dehydratase family protein	NA	NA	NA	NA
AWQ89182.1\|866921_867551_+	hypothetical protein	NA	NA	NA	NA
AWQ87660.1\|868044_869058_+	glycolytic operon regulator	NA	NA	NA	NA
AWQ87847.1\|869110_870121_+	glyceraldehyde-3-phosphate dehydrogenase, type I	NA	NA	NA	NA
AWQ87478.1\|870259_871450_+	phosphoglycerate kinase	NA	NA	NA	NA
AWQ89432.1\|871571_872333_+	triose-phosphate isomerase	NA	NA	NA	NA
AWQ88146.1\|872335_873853_+	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
AWQ89007.1\|873982_875287_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	6.7e-196	80.7
AWQ89510.1\|875623_876082_+	putative membrane protein	NA	NA	NA	NA
AWQ90002.1\|876148_876382_+	preprotein translocase, SecG subunit	NA	NA	NA	NA
AWQ88510.1\|876510_877251_+	carboxylesterase	NA	NA	NA	NA
AWQ89280.1\|877284_879657_+	ribonuclease R	Q0GXV6	Lactococcus_phage	1.9e-92	38.8
AWQ88213.1\|879678_880143_+	ssrA-binding protein	W5RAM5	Staphylococcus_phage	1.5e-81	100.0
AWQ89808.1\|880705_881824_-\|integrase	phage integrase family protein	H0UST3	Bacillus_phage	4.1e-77	44.9
AWQ89246.1\|881804_882734_-	hypothetical protein	Q9AZH9	Lactococcus_phage	2.2e-12	35.6
AWQ89939.1\|882921_883140_+	helix-turn-helix family protein	NA	NA	NA	NA
AWQ88250.1\|883152_883290_+	putative membrane protein	NA	NA	NA	NA
AWQ89645.1\|883291_883702_+	hypothetical protein	A0A2H4JBF1	uncultured_Caudovirales_phage	2.4e-59	85.8
AWQ88263.1\|883702_883996_+	hypothetical protein	A0A1W6JQH0	Staphylococcus_phage	8.9e-24	61.8
AWQ88833.1\|884083_884953_+	primase C terminal 1 family protein	A0A1W6JQL5	Staphylococcus_phage	2.7e-161	96.2
AWQ90044.1\|884969_886427_+	virulence-associated E family protein	A0A1W6JQD6	Staphylococcus_phage	1.0e-277	96.3
AWQ89232.1\|886727_887090_+	putative interference protein with phage growth	A0A1W6JQD5	Staphylococcus_phage	8.9e-66	99.2
AWQ88169.1\|887091_887376_+	putative pathogenicity island protein	A0A1W6JQE4	Staphylococcus_phage	1.0e-45	92.6
AWQ88369.1\|887372_888014_+	putative saPI1 ORF9-like protein	Q4ZE67	Staphylococcus_phage	5.9e-113	94.4
AWQ90060.1\|888530_888872_+	putative saPI1 ORF8-like protein	Q4ZE66	Staphylococcus_phage	9.3e-57	97.3
AWQ88465.1\|888883_889462_+	putative pathogenicity island protein	A0A2H4JBG0	uncultured_Caudovirales_phage	2.4e-28	38.4
AWQ87829.1\|889479_889698_+	hypothetical protein	NA	NA	NA	NA
AWQ87937.1\|889748_890276_+\|coat	putative spore coat protein	Q4ZE87	Staphylococcus_phage	6.4e-81	90.9
AWQ89388.1\|890278_890620_+	putative pathogenicity island protein	Q4ZE86	Staphylococcus_phage	8.7e-55	91.2
AWQ89437.1\|890616_891186_+\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	4.3e-99	96.3
AWQ89167.1\|891326_892319_+	abi-like family protein	A0A0S2MYH0	Enterococcus_phage	2.6e-27	29.5
AWQ88496.1\|892372_893161_+	hypothetical protein	NA	NA	NA	NA
AWQ89415.1\|893376_895023_-\|transposase	transposase DDE domain protein	Q9MBP7	Staphylococcus_prophage	3.0e-294	99.6
AWQ89627.1\|895312_895867_-	putative penicillin binding protein	A0A1W6JQE5	Staphylococcus_phage	1.8e-94	98.9
895205:895221	attR	NA	NA	NA	NA
AWQ88185.1\|896655_897456_+	enterotoxin type C-3	A0A097PAT7	Streptococcus_pyogenes_phage	6.1e-51	47.5
AWQ88135.1\|897622_898345_-	enterotoxin type E	A0A1X9H080	Staphylococcus_phage	1.2e-26	34.9
AWQ88537.1\|899184_899799_+	hypothetical protein	NA	NA	NA	NA
AWQ88554.1\|900086_900815_-	putative lipoprotein	H9A0X8	Staphylococcus_phage	4.8e-18	36.8
AWQ90039.1\|900875_902522_-\|transposase	transposase DDE domain protein	A0ZS58	Staphylococcus_virus	3.5e-295	100.0

DBSCAN-SWA_4

1016250 : 1069592

Paenibacillus_phage(33.33%)

bacteriocin,protease,integrase,tRNA,transposase

attL 1037826:1037846|attR 1060820:1060840

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ89648.1\|1016250_1017198_-\|integrase	integrase core domain protein	Q9MBM9	Staphylococcus_prophage	1.1e-184	100.0
AWQ89736.1\|1017426_1018782_+	bacterial extracellular solute-binding, 5 Middle family protein	NA	NA	NA	NA
AWQ87831.1\|1018832_1019819_+	oligopeptide/dipeptide ABC transporter, ATP-binding, C-terminal domain protein	G3M9Y6	Bacillus_virus	1.8e-15	30.0
AWQ88219.1\|1019821_1020802_+	oligopeptide/dipeptide ABC transporter, ATP-binding, C-terminal domain protein	G9BWD6	Planktothrix_phage	2.7e-16	31.6
AWQ87956.1\|1020794_1021445_+	binding-protein-dependent transport system inner membrane component family protein	NA	NA	NA	NA
AWQ89843.1\|1021456_1022338_+	binding-protein-dependent transport system inner membrane component family protein	NA	NA	NA	NA
AWQ89575.1\|1022426_1023215_-\|integrase	integrase core domain protein	A0A0C5AEA5	Paenibacillus_phage	5.1e-50	51.8
AWQ88566.1\|1023238_1023967_-	helix-turn-helix domain protein	A0A0C5AJ29	Paenibacillus_phage	4.5e-24	35.8
AWQ88054.1\|1024289_1025936_+\|transposase	transposase DDE domain protein	A0ZS58	Staphylococcus_virus	6.9e-291	99.1
AWQ87424.1\|1025962_1026952_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
AWQ89592.1\|1027246_1027642_+	regulatory protein spx	NA	NA	NA	NA
AWQ90052.1\|1028012_1028732_+	adapter protein MecA	NA	NA	NA	NA
AWQ88257.1\|1028852_1029839_+	competence CoiA-like family protein	NA	NA	NA	NA
AWQ88747.1\|1029886_1031695_+	oligoendopeptidase F	A0A1X9I5X5	Streptococcus_phage	9.3e-47	24.5
AWQ87677.1\|1032154_1032940_-	thioredoxin family protein	NA	NA	NA	NA
AWQ89441.1\|1032983_1033349_-	globin family protein	NA	NA	NA	NA
AWQ89957.1\|1033452_1034046_-	CYTH domain protein	NA	NA	NA	NA
AWQ88023.1\|1034231_1034579_+	hypothetical protein	NA	NA	NA	NA
AWQ89048.1\|1034595_1035231_+	putative RelA/SpoT domain protein	NA	NA	NA	NA
AWQ90123.1\|1035247_1036057_+	ATP-NAD kinase family protein	NA	NA	NA	NA
AWQ87362.1\|1036053_1036908_+	RNA pseudouridylate synthase family protein	NA	NA	NA	NA
AWQ89372.1\|1036928_1038314_+	magnesium transporter	NA	NA	NA	NA
1037826:1037846	attL	NA	NA	NA	NA
AWQ89340.1\|1038323_1040168_+	sodium/hydrogen exchanger family protein	NA	NA	NA	NA
AWQ88853.1\|1040445_1041216_+	enoyl-[acyl-carrier-protein] reductase [NADPH] FabI	NA	NA	NA	NA
AWQ87485.1\|1041363_1042092_+	helix-turn-helix domain protein	A0A0C5AJ29	Paenibacillus_phage	4.5e-24	35.8
AWQ88448.1\|1042115_1042904_+\|integrase	integrase core domain protein	A0A0C5AEA5	Paenibacillus_phage	5.1e-50	51.8
AWQ87488.1\|1043074_1044160_-	hypothetical protein	NA	NA	NA	NA
AWQ89389.1\|1044515_1045994_+	amino acid carrier family protein	NA	NA	NA	NA
AWQ88919.1\|1046136_1046895_+	esterase family protein	NA	NA	NA	NA
AWQ89801.1\|1047060_1047786_+	hypothetical protein	NA	NA	NA	NA
AWQ88273.1\|1047787_1048639_+	hhH-GPD superbase excision DNA repair family protein	NA	NA	NA	NA
AWQ89192.1\|1049381_1049891_+	hypothetical protein	NA	NA	NA	NA
AWQ90012.1\|1050003_1050864_-	putative glycolipid permease LtaA	NA	NA	NA	NA
AWQ89260.1\|1050874_1051090_+	hypothetical protein	NA	NA	NA	NA
AWQ89564.1\|1051171_1052347_-	processive diacylglycerol glucosyltransferase	NA	NA	NA	NA
AWQ88163.1\|1052778_1054263_+	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	NA	NA	NA	NA
AWQ89924.1\|1054252_1054504_+	yueH-like family protein	NA	NA	NA	NA
AWQ88119.1\|1054503_1056066_+	peptide chain release factor 3	A0A1S5SF82	Streptococcus_phage	2.2e-36	28.2
AWQ89698.1\|1056373_1057171_+	integral membrane, YkoY family protein	S5MAL1	Bacillus_phage	1.6e-30	40.5
AWQ88024.1\|1057404_1059714_+	trypsin-like peptidase domain protein	W5SAB9	Pithovirus	1.4e-10	27.1
AWQ88315.1\|1059730_1061089_+	cation transport family protein	NA	NA	NA	NA
1060820:1060840	attR	NA	NA	NA	NA
AWQ88101.1\|1061227_1062739_+	5'-nucleotidase, C-terminal domain protein	NA	NA	NA	NA
AWQ89545.1\|1063227_1063797_-	comK family protein	NA	NA	NA	NA
AWQ88677.1\|1064006_1064225_+	IDEAL domain protein	NA	NA	NA	NA
AWQ87822.1\|1064305_1065292_-	lipoyltransferase and lipoate-ligase family protein	NA	NA	NA	NA
AWQ88721.1\|1065490_1065667_+	hypothetical protein	NA	NA	NA	NA
AWQ89405.1\|1065681_1066284_+\|protease	CAAX protease self-immunity family protein	NA	NA	NA	NA
AWQ87427.1\|1067627_1069592_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA

DBSCAN-SWA_5

1163505 : 1247848

103

Staphylococcus_phage(64.29%)

portal,holin,tail,head,integrase,terminase,capsid,tRNA,transposase

attL 1158147:1158162|attR 1242802:1242817

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1158147:1158162	attL	NA	NA	NA	NA
AWQ88701.1\|1163505_1163988_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	5.7e-28	45.6
AWQ89747.1\|1164049_1165189_-	HIGH Nucleotidyl Transferase family protein	NA	NA	NA	NA
AWQ89542.1\|1165315_1165873_+	hypothetical protein	NA	NA	NA	NA
AWQ87608.1\|1165952_1166126_+	ribosomal protein L32	NA	NA	NA	NA
AWQ88311.1\|1166242_1167628_-	recombinase family protein	I1W625	Staphylococcus_phage	2.5e-265	100.0
AWQ89085.1\|1167834_1168515_-	pemK-like family protein	A0A2H4PQQ5	Staphylococcus_phage	1.9e-122	99.6
AWQ89831.1\|1168550_1169321_-	peptidase S24-like family protein	A0A1X9H0P5	Staphylococcus_phage	1.2e-136	96.5
AWQ89949.1\|1169725_1170169_+	hypothetical protein	A0A0H3U2S6	Staphylococcus_phage	8.9e-76	100.0
AWQ87438.1\|1170183_1170327_+	hypothetical protein	Q4ZAL7	Staphylococcus_virus	1.9e-16	100.0
AWQ88786.1\|1170316_1170526_-	hypothetical protein	W5R9J5	Staphylococcus_phage	5.9e-30	98.6
AWQ88447.1\|1170582_1171326_+	phage antirepressor KilAC domain protein	S4SW96	Staphylococcus_phage	2.3e-137	100.0
AWQ88620.1\|1171350_1171527_+	hypothetical protein	Q4ZB00	Staphylococcus_virus	3.1e-24	100.0
AWQ88160.1\|1171501_1171732_-	hypothetical protein	C8CGY3	Staphylococcus_phage	2.3e-35	100.0
AWQ87925.1\|1171781_1171919_+	hypothetical protein	S4SX85	Staphylococcus_phage	3.2e-16	100.0
AWQ89616.1\|1172166_1172427_+	hypothetical protein	Q4ZDR5	Staphylococcus_virus	5.8e-43	98.8
AWQ88674.1\|1172436_1172658_+	hypothetical protein	A0A1X9H047	Staphylococcus_phage	1.2e-33	100.0
AWQ87560.1\|1172650_1173439_+	AAA domain protein	Q4ZBM5	Staphylococcus_phage	2.6e-142	100.0
AWQ88881.1\|1173467_1174019_+	putative single-strand DNA-binding protein	Q4ZBM4	Staphylococcus_phage	3.4e-101	100.0
AWQ87809.1\|1174031_1174703_+	hypothetical protein	W5R8I8	Staphylococcus_phage	5.2e-128	100.0
AWQ88083.1\|1174809_1175658_-	hypothetical protein	W5R9J9	Staphylococcus_phage	3.8e-160	100.0
AWQ88502.1\|1175722_1176493_+	conserved phage family protein	W5R8N2	Staphylococcus_phage	6.9e-116	99.2
AWQ89235.1\|1176503_1177283_+	istB-like ATP binding family protein	A0A1X9H042	Staphylococcus_phage	1.4e-145	100.0
AWQ87889.1\|1177276_1177435_+	hypothetical protein	Q4ZBL5	Staphylococcus_phage	9.9e-22	96.2
AWQ89927.1\|1177447_1177669_+	hypothetical protein	A0A1W6JQ35	Staphylococcus_phage	1.7e-35	100.0
AWQ89663.1\|1177679_1178084_+	hypothetical protein	A0A1W6JPX0	Staphylococcus_phage	3.6e-68	100.0
AWQ88797.1\|1178088_1178274_+	hypothetical protein	Q4ZAY3	Staphylococcus_virus	1.4e-27	100.0
AWQ87990.1\|1178274_1178646_+	PVL ORF-50-like family protein	Q4ZAY2	Staphylococcus_virus	2.2e-56	99.2
AWQ88434.1\|1178646_1178895_+	phage family protein	Q4ZAY1	Staphylococcus_virus	1.4e-41	100.0
AWQ87621.1\|1178908_1179154_+	hypothetical protein	Q8SDV5	Staphylococcus_phage	1.7e-36	95.1
AWQ89774.1\|1179150_1179687_+	dUTPase family protein	Q9MBR0	Staphylococcus_prophage	4.6e-95	99.4
AWQ88826.1\|1179723_1179897_+	hypothetical protein	A0A1W6JQ45	Staphylococcus_phage	1.1e-24	98.2
AWQ88557.1\|1180030_1180159_+	hypothetical protein	A0A2H4PQJ7	Staphylococcus_phage	1.2e-14	100.0
AWQ89333.1\|1180155_1180362_+	hypothetical protein	A0A2I6PEA2	Staphylococcus_phage	3.0e-18	95.6
AWQ89001.1\|1180358_1180532_+	transcriptional activator RinB family protein	A0A0H3U4U1	Staphylococcus_phage	1.4e-21	98.2
AWQ89956.1\|1180532_1180679_+	hypothetical protein	B2ZYX7	Staphylococcus_phage	3.7e-15	97.9
AWQ88299.1\|1180702_1181125_+	phage transcriptional regulator, RinA family protein	S4V7K2	Staphylococcus_phage	1.6e-74	100.0
AWQ89380.1\|1181311_1181752_+\|terminase	terminase small subunit	I1W650	Staphylococcus_phage	4.8e-74	100.0
AWQ89579.1\|1181738_1183016_+\|terminase	phage terminase, large subunit, PBSX family	A0EWS5	Staphylococcus_virus	3.0e-249	100.0
AWQ89652.1\|1183026_1184565_+\|portal	phage portal protein, SPP1 family	S4V6D8	Staphylococcus_phage	1.9e-290	99.0
AWQ88290.1\|1184571_1185564_+\|head	phage head morphogenesis, SPP1 gp7 family domain protein	E0Y3K7	Staphylococcus_virus	3.2e-174	97.2
AWQ88927.1\|1185649_1185823_+	hypothetical protein	NA	NA	NA	NA
AWQ88819.1\|1185954_1186569_+	hypothetical protein	I1W646	Staphylococcus_phage	2.9e-40	100.0
AWQ87420.1\|1186582_1187557_+\|capsid	phage major capsid protein, HK97 family	Q8SDU5	Staphylococcus_phage	1.1e-182	99.4
AWQ89585.1\|1187578_1187866_+	hypothetical protein	S4V6D9	Staphylococcus_phage	4.7e-46	100.0
AWQ89787.1\|1187874_1188207_+\|head,tail	phage gp6-like head-tail connector family protein	E0Y3L2	Staphylococcus_virus	7.1e-54	100.0
AWQ88488.1\|1188203_1188506_+	hypothetical protein	E0Y3L3	Staphylococcus_virus	2.8e-49	96.0
AWQ87390.1\|1188505_1188853_+	hypothetical protein	I1W643	Staphylococcus_phage	5.3e-60	100.0
AWQ87502.1\|1188864_1189248_+	hypothetical protein	E0Y3L5	Staphylococcus_virus	2.6e-68	100.0
AWQ89986.1\|1189266_1189848_+\|tail	phage major tail protein, TP901-1 family	Q8SDU0	Staphylococcus_phage	4.9e-106	100.0
AWQ88081.1\|1189910_1190276_+	phage family protein	A0A0F6N4J9	Staphylococcus_phage	3.6e-59	100.0
AWQ88525.1\|1190305_1190650_+	hypothetical protein	A0A0F6N3F7	Staphylococcus_phage	2.5e-57	100.0
AWQ87595.1\|1190666_1194131_+	putative membrane protein	Q4ZDU6	Staphylococcus_virus	6.0e-268	95.1
AWQ87631.1\|1194143_1195091_+\|tail	phage tail family protein	Q8SDT6	Staphylococcus_phage	6.1e-183	99.7
AWQ89666.1\|1195099_1197001_+\|tail	prophage endopeptidase tail family protein	I1W634	Staphylococcus_phage	0.0e+00	99.7
AWQ87801.1\|1197015_1198926_+	putative minor structural protein	Q4ZDD6	Staphylococcus_virus	0.0e+00	97.3
AWQ88806.1\|1198925_1200749_+	hypothetical protein	W5R8J5	Staphylococcus_phage	1.3e-293	99.0
AWQ89720.1\|1200748_1201126_+	hypothetical protein	Q4ZDT8	Staphylococcus_virus	8.1e-54	99.2
AWQ87415.1\|1201129_1201303_+	hypothetical protein	A0A059T7K6	Staphylococcus_phage	1.3e-27	100.0
AWQ89350.1\|1201343_1201643_+	hypothetical protein	A0A0F6N3M6	Staphylococcus_phage	5.3e-40	87.9
AWQ88979.1\|1201779_1203678_+	CHAP domain protein	S4V9N2	Staphylococcus_phage	0.0e+00	98.6
AWQ88435.1\|1203690_1204863_+	hypothetical protein	A0EWN2	Staphylococcus_virus	2.7e-196	99.2
AWQ88389.1\|1204868_1205264_+	hypothetical protein	Q8SDS9	Staphylococcus_phage	1.6e-68	100.0
AWQ89030.1\|1205319_1205757_+\|holin	holin, phage phi LC3 family	B2ZZ05	Staphylococcus_phage	5.9e-72	98.6
AWQ87740.1\|1205737_1207183_+	CHAP domain protein	Q4ZB16	Staphylococcus_virus	5.0e-293	99.2
AWQ88090.1\|1207475_1208201_+	hypothetical protein	NA	NA	NA	NA
AWQ88682.1\|1208610_1210539_-	heme uptake protein IsdB	NA	NA	NA	NA
AWQ88277.1\|1210740_1211805_-	iron-regulated surface determinant protein A	NA	NA	NA	NA
AWQ87435.1\|1212013_1212697_+	heme uptake protein IsdC	NA	NA	NA	NA
AWQ88508.1\|1212696_1213773_+	putative iron-regulated protein	NA	NA	NA	NA
AWQ88318.1\|1213901_1214648_+	heme ABC transporter, heme-binding protein isdE	NA	NA	NA	NA
AWQ88064.1\|1214657_1215626_+	fecCD transport family protein	NA	NA	NA	NA
AWQ89657.1\|1215687_1216422_+	sortase, SrtB family	NA	NA	NA	NA
AWQ88953.1\|1216440_1216764_+	antibiotic biosynthesis monooxygenase family protein	NA	NA	NA	NA
AWQ87634.1\|1217147_1217888_+	RNA 2'-O ribose methyltransferase substrate binding family protein	NA	NA	NA	NA
AWQ89463.1\|1218268_1219327_+\|tRNA	phenylalanine--tRNA ligase, alpha subunit	A0A2I2L4E3	Orpheovirus	1.9e-31	35.5
AWQ87752.1\|1219326_1221729_+\|tRNA	phenylalanine--tRNA ligase, beta subunit	NA	NA	NA	NA
AWQ88501.1\|1222030_1222969_-	ribonuclease HIII	NA	NA	NA	NA
AWQ89002.1\|1223102_1223219_+	hypothetical protein	NA	NA	NA	NA
AWQ89422.1\|1223344_1223611_+	cell division ZapA family protein	NA	NA	NA	NA
AWQ88203.1\|1223611_1224133_+	colicin V production family protein	NA	NA	NA	NA
AWQ88689.1\|1224205_1225918_+	PHP domain protein	A0A2H4UV14	Bodo_saltans_virus	1.8e-15	24.3
AWQ88680.1\|1225927_1228276_+	mutS2 protein	F2QAF8	Phaeocystis_pouchetii_virus	7.2e-15	25.1
AWQ87623.1\|1228448_1228763_+	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	6.6e-25	46.6
AWQ90092.1\|1229086_1230868_+	excinuclease ABC subunit C	NA	NA	NA	NA
AWQ90022.1\|1231191_1231806_+	succinate dehydrogenase, cytochrome b556 subunit	NA	NA	NA	NA
AWQ89653.1\|1231857_1233624_+	succinate dehydrogenase/fumarate reductase, flavoprotein subunit	NA	NA	NA	NA
AWQ90017.1\|1233623_1234439_+	succinate dehydrogenase and fumarate reductase iron-sulfur family protein	NA	NA	NA	NA
AWQ89685.1\|1234677_1235478_+	glutamate racemase	NA	NA	NA	NA
AWQ89010.1\|1235489_1236077_+	non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family	NA	NA	NA	NA
AWQ88704.1\|1236069_1236573_+	phosphodiesterase, MJ0936 family protein	NA	NA	NA	NA
AWQ88102.1\|1237063_1237381_+	fibrinogen-binding protein	NA	NA	NA	NA
AWQ87457.1\|1237728_1238115_-	FPRL1 inhibitory protein	NA	NA	NA	NA
AWQ89268.1\|1238885_1239185_+	putative membrane protein	NA	NA	NA	NA
AWQ89973.1\|1239241_1240030_-\|integrase	integrase core domain protein	A0A0C5AEA5	Paenibacillus_phage	5.1e-50	51.8
AWQ88125.1\|1240053_1240782_-\|transposase	transposase family protein	A0A0C5AJ29	Paenibacillus_phage	4.5e-24	35.8
AWQ90006.1\|1241212_1241710_+	fibrinogen-binding protein	NA	NA	NA	NA
AWQ89240.1\|1241861_1242212_+	complement inhibitor	A7TWS0	Staphylococcus_phage	4.2e-20	50.0
AWQ87699.1\|1242460_1242646_-	hypothetical protein	NA	NA	NA	NA
AWQ87709.1\|1243255_1243489_-	hypothetical protein	NA	NA	NA	NA
1242802:1242817	attR	NA	NA	NA	NA
AWQ89143.1\|1243942_1244902_-	alpha-hemolysin	A0A2H4PQH7	Staphylococcus_phage	1.9e-35	30.6
AWQ88459.1\|1245569_1245716_+	putative membrane protein	NA	NA	NA	NA
AWQ89827.1\|1245699_1245900_+	hypothetical protein	Q4ZBW5	Staphylococcus_virus	1.7e-18	67.7
AWQ88414.1\|1246201_1247848_+\|transposase	transposase DDE domain protein	A0ZS58	Staphylococcus_virus	1.8e-294	99.6

DBSCAN-SWA_6

1416341 : 1426283

Staphylococcus_phage(60.0%)

head,integrase,transposase

attL 1409710:1409727|attR 1430096:1430113

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1409710:1409727	attL	NA	NA	NA	NA
AWQ89898.1\|1416341_1416539_+	cro/C1-type HTH DNA-binding domain protein	A0A1W6JNK0	Staphylococcus_phage	1.7e-10	48.4
AWQ88683.1\|1417240_1417453_+	cro/C1-type HTH DNA-binding domain protein	A0A1W6JNK0	Staphylococcus_phage	3.6e-19	72.5
AWQ88785.1\|1417749_1417956_+	hypothetical protein	A0A2H4PQT0	Staphylococcus_phage	1.9e-12	56.7
AWQ89930.1\|1419160_1419346_+	hypothetical protein	A0A0F6N3H3	Staphylococcus_phage	2.4e-19	78.7
AWQ88271.1\|1419557_1420505_-\|integrase	integrase core domain protein	Q9MBM9	Staphylococcus_prophage	1.6e-183	99.7
AWQ88456.1\|1420931_1421348_+	hypothetical protein	NA	NA	NA	NA
AWQ87481.1\|1421779_1421986_-	istB-like ATP binding family protein	A0A059NT77	Lactococcus_phage	4.5e-14	58.1
AWQ87774.1\|1422251_1422455_-\|transposase	putative transposase	NA	NA	NA	NA
AWQ87770.1\|1422470_1422602_-\|transposase	putative transposase	A0A059NT83	Lactococcus_phage	1.8e-08	58.1
AWQ89893.1\|1422869_1423121_+	hypothetical protein	NA	NA	NA	NA
AWQ88012.1\|1423325_1423847_+	hypothetical protein	A0A1J0MF61	Staphylococcus_phage	3.1e-43	51.1
AWQ88793.1\|1423848_1424046_+	hypothetical protein	NA	NA	NA	NA
AWQ90053.1\|1424205_1424790_+	hypothetical protein	NA	NA	NA	NA
AWQ88188.1\|1425116_1425314_+	hypothetical protein	A0A1J0MFV1	Staphylococcus_phage	2.3e-15	61.5
AWQ89465.1\|1425363_1425477_+	hypothetical protein	NA	NA	NA	NA
AWQ90034.1\|1425458_1425632_+	hypothetical protein	NA	NA	NA	NA
AWQ88648.1\|1425642_1425837_+	hypothetical protein	NA	NA	NA	NA
AWQ88656.1\|1426049_1426283_+\|head	putative phage head morphogenesis protein	Q4ZE35	Staphylococcus_virus	2.1e-12	76.9
1430096:1430113	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1641750 : 1647801

Streptococcus_phage(100.0%)

integrase,transposase

attL 1638758:1638771|attR 1643853:1643866

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1638758:1638771	attL	NA	NA	NA	NA
AWQ89597.1\|1641750_1642968_-\|integrase	phage integrase family protein	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
AWQ89212.1\|1643049_1643253_-	hypothetical protein	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
AWQ89780.1\|1643940_1644363_-	RNA polymerase sigma factor, sigma-70 family protein	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
1643853:1643866	attR	NA	NA	NA	NA
AWQ88097.1\|1644867_1645221_+	helix-turn-helix family protein	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
AWQ87966.1\|1645880_1647131_+\|transposase	transposase IS116/IS110/IS902 family protein	M1NSC9	Streptococcus_phage	2.0e-109	59.4
AWQ87701.1\|1647363_1647801_-	replication family protein	A0A286QS97	Streptococcus_phage	2.7e-08	62.0

DBSCAN-SWA_8

1652018 : 1665726

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ89974.1\|1652018_1653938_-	tetracycline resistance protein TetM from transposon TnFO1	A0A1S5SF82	Streptococcus_phage	0.0e+00	95.0
AWQ88520.1\|1654314_1655247_-	conjugative transposon TcpC family protein	A0A1S5SF22	Streptococcus_phage	1.1e-171	100.0
AWQ88473.1\|1655243_1656245_-	lysozyme-like family protein	A0A1S5SEZ8	Streptococcus_phage	2.5e-190	99.7
AWQ90103.1\|1656241_1658419_-	putative membrane protein	A0A1S5SF30	Streptococcus_phage	5.3e-307	85.4
AWQ87932.1\|1658421_1660869_-	AAA-like domain protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	100.0
AWQ89176.1\|1660852_1661245_-	tcpE family protein	A0A1S5SEX7	Streptococcus_phage	3.2e-69	100.0
AWQ87697.1\|1661333_1661831_-	antirestriction family protein	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
AWQ89826.1\|1661947_1662169_-	putative membrane protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
AWQ89370.1\|1662211_1663417_-	helix-turn-helix family protein	A0A1S5SEX3	Streptococcus_phage	2.8e-233	100.0
AWQ88340.1\|1663595_1664981_-	ftsK/SpoIIIE family protein	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
AWQ89873.1\|1665009_1665393_-	hypothetical protein	A0A1S5SF96	Streptococcus_phage	2.3e-64	100.0
AWQ89790.1\|1665411_1665726_-	hypothetical protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0

DBSCAN-SWA_9

1743608 : 1751920

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ87367.1\|1743608_1744394_-	ABC transporter family protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
AWQ87814.1\|1744519_1745410_-	putative endonuclease 4	A0A2H4UU70	Bodo_saltans_virus	2.0e-26	33.1
AWQ88058.1\|1745419_1746766_-	DEAD/DEAH box helicase family protein	A0A1V0SIR5	Klosneuvirus	1.4e-55	34.0
AWQ89517.1\|1746879_1747980_-	NIF3 family protein	A0A1S5V250	Saudi_moumouvirus	3.0e-08	30.6
AWQ87538.1\|1747982_1748660_-	hypothetical protein	NA	NA	NA	NA
AWQ88441.1\|1748790_1749897_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
AWQ88841.1\|1750120_1751920_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	3.5e-54	36.0

DBSCAN-SWA_10

1834526 : 1843569

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ87724.1\|1834526_1835045_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
AWQ88009.1\|1835066_1837340_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	6.2e-64	29.3
AWQ89499.1\|1837542_1839822_-	protein-export membrane protein SecD	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AWQ89636.1\|1840096_1840357_-	preprotein translocase, YajC subunit	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AWQ89667.1\|1840375_1841515_-\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
AWQ88864.1\|1841537_1842563_-\|tRNA	tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
AWQ89354.1\|1842552_1843569_-	holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_11

1973433 : 2042361

Staphylococcus_phage(93.18%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ87443.1\|1973433_1980003_-	sasC/Mrp/FmtB intercellular aggregation domain protein	A0A2H4PQU6	Staphylococcus_phage	6.4e-295	88.6
AWQ88346.1\|1980326_1980638_-	rhodanese-like domain protein	A0A2H4PQR9	Staphylococcus_phage	4.5e-50	96.1
AWQ89990.1\|1980659_1983074_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	98.8
AWQ88147.1\|1983365_1984508_-	major Facilitator Superfamily protein	A0A2H4PQR6	Staphylococcus_phage	3.5e-209	99.7
AWQ89947.1\|1984656_1985610_+	radical SAM superfamily protein	A0A2H4PQV5	Staphylococcus_phage	6.4e-79	99.3
AWQ89065.1\|1985606_1986170_+	rRNA methylase family protein	A0A2H4PQV0	Staphylococcus_phage	1.1e-99	95.7
AWQ88548.1\|1986288_1986690_-	HTH-type transcriptional regulator rot	NA	NA	NA	NA
AWQ87758.1\|1987262_1988090_-	alpha/beta hydrolase family protein	NA	NA	NA	NA
AWQ87856.1\|1988323_1989325_+	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	5.0e-183	99.1
AWQ89281.1\|1989446_1989911_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.9e-69	98.1
AWQ88214.1\|1989923_1991105_-	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
AWQ87721.1\|1991115_1991748_-	riboflavin synthase, alpha subunit	A0A2H4PQS5	Staphylococcus_phage	8.4e-112	99.0
AWQ89118.1\|1991754_1992798_-	riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	5.9e-195	98.3
AWQ87374.1\|1993278_1994781_-	FAD-NAD(P)-binding family protein	A0A2H4PQX2	Staphylococcus_phage	5.0e-30	98.6
AWQ87811.1\|1995737_1997030_+	arsenite/antimonite efflux pump membrane family protein	A0A2H4PQU3	Staphylococcus_phage	2.9e-215	94.7
AWQ88269.1\|1997116_1997971_-	mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AWQ88131.1\|1998246_1998471_-	hypothetical protein	NA	NA	NA	NA
AWQ87991.1\|1998669_1999140_+	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	7.7e-70	85.8
AWQ89486.1\|1999456_1999696_+	comK family protein	NA	NA	NA	NA
AWQ89765.1\|1999682_2000126_-	putative membrane protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-49	77.4
AWQ88121.1\|2000423_2001059_+\|protease	CAAX protease self-immunity family protein	NA	NA	NA	NA
AWQ89233.1\|2001225_2001846_+\|protease	CAAX protease self-immunity family protein	NA	NA	NA	NA
AWQ87433.1\|2002303_2003017_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AWQ88391.1\|2003428_2003578_+	putative membrane protein	NA	NA	NA	NA
AWQ87751.1\|2003832_2004198_+	crcB-like family protein	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
AWQ89740.1\|2004194_2004548_+	crcB-like family protein	A0A2H4PQQ7	Staphylococcus_phage	4.2e-20	97.4
AWQ88876.1\|2004797_2005631_-	aldo/keto reductase family protein	A0A2H4PQR8	Staphylococcus_phage	7.8e-158	99.3
AWQ89707.1\|2005842_2006751_-	nuclease-related domain protein	A0A2H4PQQ8	Staphylococcus_phage	9.8e-138	99.7
AWQ88776.1\|2006875_2008069_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
AWQ88914.1\|2008440_2010033_+	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
AWQ88696.1\|2010325_2011096_-	prolyl oligopeptidase family protein	A0A2H4PQM6	Staphylococcus_phage	3.4e-139	97.2
AWQ88621.1\|2011076_2011556_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	3.0e-85	98.7
AWQ89317.1\|2011615_2011873_+	putative membrane protein insertion efficiency factor	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AWQ88625.1\|2011869_2012871_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	8.5e-183	96.7
AWQ88988.1\|2012875_2014354_-	O-succinylbenzoate-CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.4e-282	97.2
AWQ88821.1\|2014512_2014995_-	hypothetical protein	A0A2H4PQN7	Staphylococcus_phage	2.8e-75	94.5
AWQ88912.1\|2015306_2015921_+	excalibur calcium-binding domain protein	A0A2H4PQM8	Staphylococcus_phage	3.6e-43	87.3
AWQ89329.1\|2016001_2017018_+	hypothetical protein	A0A2H4PQN2	Staphylococcus_phage	6.6e-74	97.2
AWQ88486.1\|2017093_2017720_+	putative lipoprotein	A0A2H4PQM7	Staphylococcus_phage	4.5e-81	84.1
AWQ88651.1\|2017760_2018105_+	hypothetical protein	A0A2H4PQN6	Staphylococcus_phage	5.1e-55	94.7
AWQ89805.1\|2018202_2018775_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.2e-25	94.8
AWQ89297.1\|2018923_2020291_-	FRG domain protein	NA	NA	NA	NA
AWQ89229.1\|2020290_2020860_-	hypothetical protein	A0A2H4PQN8	Staphylococcus_phage	2.2e-39	54.8
AWQ88498.1\|2021052_2021499_-	hypothetical protein	NA	NA	NA	NA
AWQ88348.1\|2022442_2022886_-	hypothetical protein	NA	NA	NA	NA
AWQ88574.1\|2022885_2023329_-	hypothetical protein	NA	NA	NA	NA
AWQ90093.1\|2023328_2023583_-	hypothetical protein	NA	NA	NA	NA
AWQ88523.1\|2023651_2023771_-	hypothetical protein	NA	NA	NA	NA
AWQ89103.1\|2024295_2026716_+	polysaccharide lyase family 8, N terminal alpha-helical domain protein	NA	NA	NA	NA
AWQ89054.1\|2026841_2027219_-	hypothetical protein	NA	NA	NA	NA
AWQ89023.1\|2027428_2027806_-	hypothetical protein	NA	NA	NA	NA
AWQ89958.1\|2027959_2029531_+	hypothetical protein	NA	NA	NA	NA
AWQ87429.1\|2029545_2029845_+	virulence factor EsxB family protein	NA	NA	NA	NA
AWQ88932.1\|2030106_2031924_-	AAA domain protein	NA	NA	NA	NA
AWQ89644.1\|2031960_2033115_-	type I restriction modification DNA specificity domain protein	A0A2H4PQP5	Staphylococcus_phage	7.8e-39	36.3
AWQ88175.1\|2033107_2034664_-	type I restriction-modification system, M subunit	A0A2H4PQP4	Staphylococcus_phage	2.2e-286	98.6
AWQ89419.1\|2035026_2035746_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.0e-129	98.3
AWQ90007.1\|2035915_2036632_-\|protease	serine protease SplF	A0A2H4PQN5	Staphylococcus_phage	6.6e-129	97.1
AWQ89185.1\|2036795_2037512_-\|protease	serine protease SplB	A0A2H4PQN5	Staphylococcus_phage	2.4e-86	64.7
AWQ88514.1\|2037678_2038395_-\|protease	serine protease SplF	A0A2H4PQN5	Staphylococcus_phage	5.5e-83	62.6
AWQ89723.1\|2038518_2039238_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	6.4e-124	93.7
AWQ87589.1\|2039295_2039445_-\|protease	serine protease SplB domain protein	A0A2H4PQN0	Staphylococcus_phage	5.3e-17	97.7
AWQ89288.1\|2040037_2040154_+	hypothetical protein	NA	NA	NA	NA
AWQ89335.1\|2040252_2040768_+	hypothetical protein	NA	NA	NA	NA
AWQ87825.1\|2041014_2042361_+	hypothetical protein	M1NRY5	Streptococcus_phage	6.7e-66	51.3

DBSCAN-SWA_12

2161692 : 2236875

Staphylococcus_phage(91.78%)

portal,holin,tail,protease,head,integrase,capsid,transposase

attL 2201814:2201831|attR 2226640:2226657

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ88972.1\|2161692_2163372_-\|transposase	transposase DDE domain protein	A0ZS58	Staphylococcus_virus	1.8e-238	77.1
AWQ89695.1\|2163860_2164271_+	yolD-like family protein	U3PG23	Staphylococcus_phage	1.4e-30	54.2
AWQ88006.1\|2164299_2164665_-	putative cTP synthase	NA	NA	NA	NA
AWQ87823.1\|2164673_2166737_-\|integrase	phage integrase family protein	NA	NA	NA	NA
AWQ89829.1\|2166739_2167852_-\|integrase	phage integrase family protein	P97010	Streptococcus_pyogenes_phage	9.6e-10	30.5
AWQ87391.1\|2168129_2168342_+	yolD-like family protein	NA	NA	NA	NA
AWQ87681.1\|2168398_2168572_-	hypothetical protein	NA	NA	NA	NA
AWQ88710.1\|2169022_2170063_+	6-aminopenicillanic acid acyl-transferase family protein	NA	NA	NA	NA
AWQ87365.1\|2170119_2170962_-	hypothetical protein	NA	NA	NA	NA
AWQ89985.1\|2170958_2171516_-	hypothetical protein	NA	NA	NA	NA
AWQ89356.1\|2171575_2172100_-	hypothetical protein	NA	NA	NA	NA
AWQ87711.1\|2172220_2172784_+	putative thioredoxin	NA	NA	NA	NA
AWQ89374.1\|2172847_2173588_-	ABC-2 transporter family protein	NA	NA	NA	NA
AWQ88046.1\|2173587_2174460_-	ABC transporter family protein	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
AWQ88142.1\|2174456_2175137_-	ABC-2 transporter family protein	NA	NA	NA	NA
AWQ88584.1\|2175137_2176034_-	AAA domain protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
AWQ88022.1\|2176030_2176411_-	bacterial regulatory, gntR family protein	NA	NA	NA	NA
AWQ88136.1\|2176668_2176845_-	putative membrane protein	NA	NA	NA	NA
AWQ87605.1\|2177384_2178671_+	aminotransferase class I and II family protein	NA	NA	NA	NA
AWQ89287.1\|2178941_2180681_-	protein map	NA	NA	NA	NA
AWQ89110.1\|2181066_2181267_+	phospholipase C domain protein	A0A1P8L6A7	Staphylococcus_phage	3.8e-26	95.4
AWQ89485.1\|2182197_2182389_+	putative membrane protein	M9NS66	Staphylococcus_phage	1.7e-23	100.0
AWQ87959.1\|2182441_2182792_-	complement inhibitor	A7TWS0	Staphylococcus_phage	7.5e-54	100.0
AWQ89201.1\|2183474_2183924_+	chemotaxis inhibitory protein	A0A075LZI2	Staphylococcus_phage	8.7e-79	100.0
AWQ89913.1\|2184018_2184225_-	bacterial SH3 domain protein	A0A2I6PF47	Staphylococcus_phage	2.1e-32	97.1
AWQ89066.1\|2185003_2185495_-	staphylokinase	A0A075LYD3	Staphylococcus_phage	8.0e-86	100.0
AWQ89074.1\|2185685_2186441_-	CHAP domain protein	A0A075LZV3	Staphylococcus_phage	1.2e-152	100.0
AWQ88567.1\|2186452_2186707_-\|holin	holin, phage phi LC3 family	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
AWQ89127.1\|2186918_2187053_-	putative membrane protein	D2JLG3	Staphylococcus_phage	9.3e-13	100.0
AWQ90036.1\|2187297_2188080_-	enterotoxin type E	A0A075M4C7	Staphylococcus_phage	1.6e-149	99.6
AWQ88946.1\|2188491_2188866_-	putative membrane protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
AWQ89820.1\|2188921_2189209_-	hypothetical protein	A0A1X9H0N7	Staphylococcus_phage	7.6e-44	100.0
AWQ87559.1\|2189254_2189407_-	putative phage protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
AWQ88802.1\|2189399_2193182_-	phage minor structural, N-terminal region domain protein	A0A068A201	Staphylococcus_phage	0.0e+00	99.8
AWQ88529.1\|2193197_2194682_-\|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	1.2e-297	100.0
AWQ87447.1\|2194678_2199208_-\|tail	phage tail tape measure protein, TP901 family, core region	A0A2I6PDK2	Staphylococcus_phage	0.0e+00	99.3
AWQ89858.1\|2199264_2199402_-	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	3.4e-18	100.0
AWQ88291.1\|2199452_2199803_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
AWQ89859.1\|2199852_2199993_-	bacterial Ig-like domain family protein	A0A2I6PDK6	Staphylococcus_phage	2.5e-16	100.0
AWQ89306.1\|2200118_2200763_-\|tail	phage major tail, phi13 family protein	G4KNQ7	Staphylococcus_phage	6.5e-120	100.0
AWQ87995.1\|2200763_2201171_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
AWQ89933.1\|2201167_2201572_-	hypothetical protein	G4KNQ5	Staphylococcus_phage	4.3e-69	100.0
AWQ89713.1\|2201568_2201931_-\|head,tail	phage head-tail joining family protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
2201814:2201831	attL	NA	NA	NA	NA
AWQ88835.1\|2201914_2202199_-\|head,tail	phage gp6-like head-tail connector family protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
AWQ88532.1\|2202188_2202473_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
AWQ87742.1\|2202492_2203638_-\|capsid	phage major capsid protein, HK97 family	G4KNQ3	Staphylococcus_phage	3.6e-214	99.7
AWQ87723.1\|2203661_2204399_-\|protease	clp protease family protein	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
AWQ89377.1\|2204382_2205570_-\|portal	phage portal protein, HK97 family	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
AWQ89420.1\|2205585_2207247_-	phage Terminase family protein	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
AWQ88354.1\|2207243_2207588_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
AWQ89809.1\|2207717_2208017_-	HNH endonuclease family protein	A0A2I6PDH9	Staphylococcus_phage	3.5e-52	100.0
AWQ89455.1\|2208248_2208665_-	phage transcriptional regulator, RinA family protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
AWQ89472.1\|2208692_2208893_-	hypothetical protein	D2JLD9	Staphylococcus_phage	5.3e-28	98.5
AWQ90013.1\|2208892_2209042_-	transcriptional activator RinB family protein	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
AWQ87799.1\|2209038_2209245_-	hypothetical protein	A0A2I6PEA2	Staphylococcus_phage	1.1e-17	94.1
AWQ88711.1\|2209241_2209376_-	hypothetical protein	A0A2H4PQJ7	Staphylococcus_phage	9.9e-15	97.7
AWQ88208.1\|2209523_2210060_-	dUTPase family protein	Q9MBR0	Staphylococcus_prophage	1.6e-95	100.0
AWQ88663.1\|2210056_2210302_-	hypothetical protein	Q8SDV5	Staphylococcus_phage	1.7e-36	95.1
AWQ87512.1\|2210316_2210559_-	phage family protein	Q4ZDP7	Staphylococcus_virus	1.2e-39	97.5
AWQ89436.1\|2210561_2210819_-	hypothetical protein	A0A1X9H067	Staphylococcus_phage	6.3e-42	98.8
AWQ89999.1\|2210818_2211190_-	PVL ORF-50-like family protein	A0A2I6PDG3	Staphylococcus_phage	1.4e-50	91.1
AWQ89133.1\|2211202_2211607_-	endodeoxyribonuclease RusA family protein	A0A075M042	Staphylococcus_phage	8.4e-73	100.0
AWQ89578.1\|2211615_2211834_-	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	8.9e-37	98.6
AWQ88774.1\|2211840_2212074_-	initiator Replication family protein	A0A2I6PDG7	Staphylococcus_phage	4.0e-35	98.7
AWQ88868.1\|2212300_2212465_-	replication initiation and membrane attachment protein, DnaB/DnaD family	A0A2I6PDG7	Staphylococcus_phage	1.3e-13	100.0
AWQ88583.1\|2212752_2213223_-	single-stranded DNA-binding family protein	A0A1P8L6D9	Staphylococcus_phage	5.7e-81	100.0
AWQ89153.1\|2213223_2213709_-	beta-lactamase superfamily domain protein	A0A1P8L6F7	Staphylococcus_phage	9.4e-87	100.0
AWQ89835.1\|2213921_2214842_-	recT family protein	A0A1P8L6F6	Staphylococcus_phage	5.1e-166	100.0
AWQ88381.1\|2214843_2216787_-	hypothetical protein	A0A1P8L6F1	Staphylococcus_phage	0.0e+00	99.7
AWQ89016.1\|2217067_2217328_-	hypothetical protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
AWQ89175.1\|2217332_2217635_-	hypothetical protein	A0A1P8L6F8	Staphylococcus_phage	7.0e-48	100.0
AWQ88251.1\|2217887_2218211_-	hypothetical protein	A0A075LYF5	Staphylococcus_phage	3.0e-57	100.0
AWQ88579.1\|2218265_2218646_+	hypothetical protein	Q9T1Z5	Staphylococcus_phage	1.2e-68	100.0
AWQ88481.1\|2218632_2218830_-	putative phi PVL orf 35-like protein	O80075	Staphylococcus_phage	2.5e-30	100.0
AWQ88668.1\|2218845_2219598_-	phage antirepressor KilAC domain protein	M9NTH5	Staphylococcus_phage	1.1e-139	100.0
AWQ90125.1\|2219648_2219978_+	hypothetical protein	M9NS98	Staphylococcus_phage	5.1e-52	98.2
AWQ89552.1\|2220197_2220461_-	helix-turn-helix family protein	A0A2I6PF09	Staphylococcus_phage	7.2e-41	100.0
AWQ87446.1\|2220594_2221308_+	peptidase S24-like family protein	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
AWQ89087.1\|2221323_2222256_+	exonuclease family protein	A0A2I6PEZ7	Staphylococcus_phage	5.7e-173	100.0
AWQ87558.1\|2222261_2222603_+	hypothetical protein	A0A2I6PF04	Staphylococcus_phage	4.6e-56	100.0
AWQ89351.1\|2222806_2222989_+	hypothetical protein	A0A2I6PDF8	Staphylococcus_phage	6.9e-27	100.0
AWQ87361.1\|2223088_2224072_+	glycosyl transferase 2 family protein	NA	NA	NA	NA
AWQ87815.1\|2224082_2224325_+	hypothetical protein	NA	NA	NA	NA
AWQ87796.1\|2224387_2225425_+\|integrase	integrase	Q38086	Staphylococcus_phage	6.7e-175	98.3
AWQ88304.1\|2225481_2226306_+	sphingomyelin phosphodiesterase	A0A1P8L6H7	Staphylococcus_phage	9.8e-161	99.6
AWQ88661.1\|2226562_2227582_-	leucotoxin LukDv	A0A2I6PEU3	Staphylococcus_phage	3.4e-54	39.6
2226640:2226657	attR	NA	NA	NA	NA
AWQ87395.1\|2227603_2228659_-	hypothetical protein	A0A2I6PER8	Staphylococcus_phage	7.9e-38	34.6
AWQ87843.1\|2229090_2229774_+	putative succinyl-diaminopimelate desuccinylase	NA	NA	NA	NA
AWQ88503.1\|2229785_2230313_+	peptidase dimerization domain protein	NA	NA	NA	NA
AWQ88705.1\|2230751_2232059_+	ktr system potassium uptake protein B	NA	NA	NA	NA
AWQ88870.1\|2232636_2232978_-	putative phage-like protein	C8CH40	Staphylococcus_phage	4.1e-20	46.0
AWQ88286.1\|2233980_2235597_-	chaperonin GroL	A0A240F779	uncultured_virus	2.6e-157	54.7
AWQ88140.1\|2235672_2235957_-	10 kDa chaperonin	A0A221S386	uncultured_virus	4.7e-14	46.2
AWQ89418.1\|2236131_2236875_+\|protease	CAAX protease self-immunity family protein	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: CP029653.1|AWQ88131.1|1998246_1998471_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

CP029653.1|AWQ88131.1|1998246_1998471_-|hypothetical-protein

1998246_1998471_-

74 aa aa

1973433-2042361

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
CP029653_12	Orphan	12.1\|2956978\|32\|CP029653\|CRISPRCasFinder	2956978-2957009	32	2002173-2002142	2

1. spacer 12.1|2956978|32|CP029653|CRISPRCasFinder matches to CP029653 position: 2002173-2002142, mismatch: 2

acaccctaactcgcattgcctgtagaatttct	CRISPR spacer
acaccccaacgcgcattgcctgtagaatttct	Protospacer
******.*** *********************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP029653

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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