CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP029649	Staphylococcus aureus strain AR_0472 chromosome, complete genome	10 crisprs	DinG,DEDDh,cas3,cas6,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas2,cas1,WYL,csa3	5	13	9	0
CP029648	Staphylococcus aureus strain AR_0472 plasmid unnamed1, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: CP029649_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029649_1

649777-649862

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029649_1

>merge|CP029649|1|649777-649862|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTCCGCCAGCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>CP029649|1|1|649777-649862|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	CCGCCAGCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
CP029649.1\|AWQ65312.1\|651045_652005_+\|alpha-hemolysin	unknown	unknown	gnl\|CDD\|273388
CP029649.1\|AWQ65374.1\|642575_642803_-\|putative-membrane-protein	unknown	unknown	unknown
CP029649.1\|AWQ66061.1\|644837_645770_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|237071
CP029649.1\|AWQ65798.1\|650226_650373_-\|putative-membrane-protein	unknown	unknown	unknown
CP029649.1\|AWQ67372.1\|653336_653522_+\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ65240.1\|656986_657103_-\|putative-membrane-protein	unknown	unknown	unknown
CP029649.1\|AWQ67711.1\|656500_656896_+\|FPRL1-inhibitory-protein	unknown	unknown	gnl\|CDD\|171849
CP029649.1\|AWQ65734.1\|645792_646794_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|235269
CP029649.1\|AWQ66721.1\|647231_647957_+\|toxin-beta-grasp-domain-protein	unknown	unknown	gnl\|CDD\|171855
CP029649.1\|AWQ65751.1\|655321_655828_-\|putative-membrane-protein	unknown	unknown	unknown
CP029649.1\|AWQ65493.1\|640886_641075_-\|putative-dNA-binding-protein	unknown	unknown	gnl\|CDD\|225382
CP029649.1\|AWQ67563.1\|648884_649601_+\|toxin-beta-grasp-domain-protein	unknown	unknown	gnl\|CDD\|171995
CP029649.1\|AWQ65667.1\|654565_655063_-\|fibrinogen-binding-protein	unknown	unknown	gnl\|CDD\|289007
CP029649.1\|AWQ67422.1\|641323_642271_+\|C4-dicarboxylate-transporter/malic-acid-transport-family-protein	unknown	unknown	gnl\|CDD\|187765
CP029649.1\|AWQ65907.1\|652481_652715_+\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ65764.1\|654061_654412_-\|complement-inhibitor	unknown	unknown	gnl\|CDD\|371594
CP029649.1\|AWQ65211.1\|648051_648777_+\|toxin-beta-grasp-domain-protein	unknown	unknown	gnl\|CDD\|106307
CP029649.1\|AWQ66102.1\|643109_644666_-\|C4-dicarboxylate-anaerobic-carrier-family-protein	unknown	unknown	gnl\|CDD\|224207
CP029649.1\|AWQ67537.1\|650045_650243_-\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ65642.1\|639637_640519_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226192

Protein	Function_ID	Function_description	E-value
CP029649.1\|AWQ65312.1\|651045_652005_+\|alpha-hemolysin	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	1.66722e-141
CP029649.1\|AWQ67563.1\|648884_649601_+\|toxin-beta-grasp-domain-protein	gnl\|CDD\|171995	PRK13350, PRK13350, superantigen-like protein; Reviewed.	5.01863e-153
CP029649.1\|AWQ66061.1\|644837_645770_-\|carbamate-kinase	gnl\|CDD\|237071	PRK12353, PRK12353, putative amino acid kinase; Reviewed.	0
CP029649.1\|AWQ67711.1\|656500_656896_+\|FPRL1-inhibitory-protein	gnl\|CDD\|171849	PRK13033, PRK13033, formyl peptide receptor-like 1 inhibitory protein; Reviewed.	1.17946e-62
CP029649.1\|AWQ65734.1\|645792_646794_-\|ornithine-carbamoyltransferase	gnl\|CDD\|235269	PRK04284, PRK04284, ornithine carbamoyltransferase; Provisional.	0
CP029649.1\|AWQ66721.1\|647231_647957_+\|toxin-beta-grasp-domain-protein	gnl\|CDD\|171855	PRK13043, PRK13043, superantigen-like protein; Reviewed.	1.59495e-161
CP029649.1\|AWQ65493.1\|640886_641075_-\|putative-dNA-binding-protein	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	0.00787195
CP029649.1\|AWQ65642.1\|639637_640519_-\|hypothetical-protein	gnl\|CDD\|226192	COG3666, COG3666, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	4.41106e-37
CP029649.1\|AWQ67422.1\|641323_642271_+\|C4-dicarboxylate-transporter/malic-acid-transport-family-protein	gnl\|CDD\|187765	cd09325, TDT_C4-dicarb_trans, C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. This subfamily contains bacterial C4-dicarboxylate transporters, which is part of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family. It includes Tellurite resistance protein tehA; the tehA gene encodes an integral membrane protein that has been shown to have efflux activity of quaternary ammonium compounds. TehA protein of Escherichia coli functions as a tellurite-resistance uptake permease.	7.21166e-84
CP029649.1\|AWQ65764.1\|654061_654412_-\|complement-inhibitor	gnl\|CDD\|371594	pfam11546, CompInhib_SCIN, Staphylococcal complement inhibitor SCIN. SCIN is released by Staphylococcus aureus to counteract the host immune defense. The protein binds to and inhibits C3 convertases on the bacterial surface, reducing phagocytosis and blocking downstream effector functions by C3b deposition on its surface. An 18 residue stretch 31-48 is crucial for SCIN activity.	2.0882e-48
CP029649.1\|AWQ65211.1\|648051_648777_+\|toxin-beta-grasp-domain-protein	gnl\|CDD\|106307	PRK13349, PRK13349, superantigen-like protein; Reviewed.	2.07034e-148
CP029649.1\|AWQ66102.1\|643109_644666_-\|C4-dicarboxylate-anaerobic-carrier-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
CP029649.1\|AWQ65667.1\|654565_655063_-\|fibrinogen-binding-protein	gnl\|CDD\|289007	pfam12199, efb-c, Extracellular fibrinogen binding protein C terminal. This domain family is found in bacteria, and is approximately 70 amino acids in length. There is a conserved VLK sequence motif. It is the C terminal domain of bacterial extracellular fibrinogen binding protein. It contains a helical motif involved in complement regulation. This motif binds to complement and changes its conformation to a form which cannot activate downstream components of the complement cascade.	5.38388e-27

>CP029649.1|AWQ67563.1|648884_649601_+|toxin-beta-grasp-domain-protein
MCKNITKNIILTTTLLLLGTVLPQNQKPVFSFYSEAKAYSIGQDETNINELIKYYTQPHFSFSNKWLYQYDNGNIYVELKRYSWSAHISLWGAESWGNINQLKDRYVDVFGLKDKDTDQLWWSYRETFTGGVTPAAKPSDKTYNLFVQYKDKLQTIIGAHKIYQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNYTIDLSKRLHSDLANVYVKNPNKITVDVLFD
>CP029649.1|AWQ65211.1|648051_648777_+|toxin-beta-grasp-domain-protein
MNNNITKKIILSTTLLLLGTASTQFPNTPINSSSEAKAYYINQNETNVNELTKYYSQKYLTFSNSTLWQKDNGTIHATLLQFSWYSHIQVYGPESWGNINQLRNKSVDIFGIKDHETIDSFALSQETFTGGVTPAATSNDKHYKLNVTYKDKAETFTGGFPVYEGNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNNYTIDLSKRLPSTDANRYVKKPQNAKIEVILEKSN
>CP029649.1|AWQ66721.1|647231_647957_+|toxin-beta-grasp-domain-protein
MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISENETNINELIKYYTQPHLSLSNKWLWQKPNGSIHATLQTWVWYSHIQVFGSESWGNINQLRNKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKPYRLFLKYSDKQQTIIGGHEFYKGNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKITADGNNYTIDLSKKLKLTDTNRYVKNPKNAQIEVILEKSN
>CP029649.1|AWQ65734.1|645792_646794_-|ornithine-carbamoyltransferase
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF
>CP029649.1|AWQ66061.1|644837_645770_-|carbamate-kinase
MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVISHGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDKQVVTLVTQVEVDENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVPSPQPISIIELESIKTLIKNDTFVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLGANIQCDQLIILTAIDYVYINFNTENQQPLKTTNVDELKRYIDENQFAKGSMLPKIEAAISFIENNPKGSVLITSLNELDAALEGKVGTVIKK
>CP029649.1|AWQ66102.1|643109_644666_-|C4-dicarboxylate-anaerobic-carrier-family-protein
MENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAYSKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTYERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKTKGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASSVGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKKDPKASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVMASAFLIFTIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEGMISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTVGIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGGLLITQVLIYS
>CP029649.1|AWQ65374.1|642575_642803_-|putative-membrane-protein
MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWNLRWYLLENIPHLPIILFILMFIFGVPSEMIKDRQRKNNGV
>CP029649.1|AWQ67422.1|641323_642271_+|C4-dicarboxylate-transporter/malic-acid-transport-family-protein
MRLQKAPLVTSGLVLGLLGLGNLLKDLSLTLNAVCGIFAFLIWIHLLCTMIKYFNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIWILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTVIYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVIIFLLLAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKGLLFIEVLLATVIVLRVFIGYLHFFLKKENQDKFLRNASQ
>CP029649.1|AWQ65493.1|640886_641075_-|putative-dNA-binding-protein
MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKNERSLDNMSLKNAELLYKFANSIFSNEN
>CP029649.1|AWQ65642.1|639637_640519_-|hypothetical-protein
MYKNYSMTQLTLLIETSVRIPQNDISRYVNEIVETIPDSEFDEFRHHRGATSYHPKMILKIILYAYTQSVFSGRKIEKLLHDSIRMMWLAQNQTPSYKTINRFRVNSNTDALIESLFIQFHSQCLKQNLIDNNSIFIDGTKVEANANRYTFVWKKSIQNHESKLNENSKALYRDLVEEKIIPEIKEDGDSDLTIEEIDLIGSHLDKEIEDLNHSIDNEDCAQIRKQTRKKRTEIKKFKKKFDDYSERKSKYEEQKSILKDRNSFSKTDHDATFMRMKEDHMKNGNLSQDTIYK
>CP029649.1|AWQ67537.1|650045_650243_-|hypothetical-protein
MTELNNIINSLQSLFESESGYKISKNSGVPYQTVQDLRNGKTKLEDARFRTIIKLYSYYVSLKEH
>CP029649.1|AWQ65798.1|650226_650373_-|putative-membrane-protein
MKLFYIVFLIIIWLNIFLGNEIIHTLTVLITTLYIVNSRKGIKNDRVE
>CP029649.1|AWQ65312.1|651045_652005_+|alpha-hemolysin
MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNTTVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDTGKIGGLIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN
>CP029649.1|AWQ65907.1|652481_652715_+|hypothetical-protein
MVFNDWEINVVYSGEHEVVANEKSLFVIDEFYDVAIAIYYLDGKLKVAHVNYGSDFTIDVANKVFELNIKNPNVDEH
>CP029649.1|AWQ67372.1|653336_653522_+|hypothetical-protein
MNKHINKKAAKLLEDYKKVQQRKSKETDRGCLKSVIMLIVLFFLIIFGIVACSTNVNFFFQ
>CP029649.1|AWQ65764.1|654061_654412_-|complement-inhibitor
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>CP029649.1|AWQ65667.1|654565_655063_-|fibrinogen-binding-protein
MKNKLIAKSLLTIAAIGITTTTIASTADASEGYGPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFKHDYNILEFNDGTFEYGARPQFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQKAVNLVSFEYKVKKMVLQERIDNVLKQGLVK
>CP029649.1|AWQ65751.1|655321_655828_-|putative-membrane-protein
MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYISLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVVLEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIFNYRMRSYK
>CP029649.1|AWQ67711.1|656500_656896_+|FPRL1-inhibitory-protein
MKKNITKVIIASTVIATGLLTHSNDAKAFFSYEWKGLEIAKKLADDEKKDEERADRLIKDAEKERTYTGKTVEDLYVIAKKLGKGNTIAVVRIIDGGKNGYYTFDITRPLEEHRKNIKVVAKGEIDSITWY
>CP029649.1|AWQ65240.1|656986_657103_-|putative-membrane-protein
MAIVKRKSNVLTIIKIVTDIVATVLIIRALLNSRKDAK

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Crispr_ID: CP029649_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029649_2

672608-672699

Orphan

Consensus_repeat	Method
CCTCTTTGATTTTTAATCATTAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029649_2

>merge|CP029649|2|672608-672699|CRISPRCasFinder
CCTCTTTGATTTTTAATCATTAGAGGCTTTTATGCAGTGATGCGAAGCATCATCTGTATTCCGCTGTTCCTCTTTGATTTTTAATCATTATG

>CP029649|2|2|672608-672699|CRISPRCasFinder
CCTCTTTGATTTTTAATCATTAGA	GGCTTTTATGCAGTGATGCGAAGCATCATCTGTATTCCGCTGTT
CCTCTTTGATTTTTAATCATTATG

Protein	Signature genes	Signature genes Name	Protein_function
CP029649.1\|AWQ66432.1\|668734_670447_-\|PHP-domain-protein	unknown	unknown	gnl\|CDD\|236311
CP029649.1\|AWQ66368.1\|682081_682765_-\|heme-uptake-protein-IsdC	unknown	unknown	gnl\|CDD\|274705
CP029649.1\|AWQ66177.1\|665889_666204_-\|thioredoxin	unknown	unknown	gnl\|CDD\|200072
CP029649.1\|AWQ67739.1\|661028_662795_-\|succinate-dehydrogenase/fumarate-reductase,-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|236319
CP029649.1\|AWQ65230.1\|666376_668725_-\|mutS2-protein	unknown	unknown	gnl\|CDD\|234750
CP029649.1\|AWQ66656.1\|675452_676511_-\|phenylalanine--tRNA-ligase,-alpha-subunit	unknown	unknown	gnl\|CDD\|234780
CP029649.1\|AWQ66499.1\|678356_679091_-\|sortase,-SrtB-family	unknown	unknown	gnl\|CDD\|226898
CP029649.1\|AWQ66939.1\|671041_671308_-\|cell-division-ZapA-family-protein	unknown	unknown	gnl\|CDD\|172616
CP029649.1\|AWQ65784.1\|681005_682082_-\|iron-(Fe+3)-ABC-superfamily-ATP-binding-cassette-transporter	unknown	unknown	unknown
CP029649.1\|AWQ66492.1\|673050_675453_-\|phenylalanine--tRNA-ligase,-beta-subunit	unknown	unknown	gnl\|CDD\|234804
CP029649.1\|AWQ66077.1\|680130_680877_-\|heme-ABC-transporter,-heme-binding-protein-isdE	unknown	unknown	gnl\|CDD\|274706
CP029649.1\|AWQ65808.1\|659177_659978_-\|glutamate-racemase	unknown	unknown	gnl\|CDD\|234851
CP029649.1\|AWQ65155.1\|670519_671041_-\|colicin-V-production-family-protein	unknown	unknown	gnl\|CDD\|224205
CP029649.1\|AWQ67069.1\|662846_663461_-\|succinate-dehydrogenase,-cytochrome-b556-subunit	unknown	unknown	gnl\|CDD\|239577
CP029649.1\|AWQ67653.1\|679152_680118_-\|fecCD-transport-family-protein	unknown	unknown	gnl\|CDD\|223682
CP029649.1\|AWQ66536.1\|676890_677631_-\|spoU-rRNA-Methylase-family-protein	unknown	unknown	gnl\|CDD\|223640
CP029649.1\|AWQ65833.1\|678014_678338_-\|antibiotic-biosynthesis-monooxygenase-family-protein	unknown	unknown	gnl\|CDD\|139480
CP029649.1\|AWQ67398.1\|663784_665566_-\|excinuclease-ABC-subunit-C	unknown	unknown	gnl\|CDD\|234792
CP029649.1\|AWQ65431.1\|682973_684026_+\|iron-regulated-surface-determinant-protein-A	unknown	unknown	gnl\|CDD\|227676
CP029649.1\|AWQ67187.1\|660213_661029_-\|succinate-dehydrogenase-and-fumarate-reductase-iron-sulfur-family-protein	unknown	unknown	gnl\|CDD\|181515

Protein	Function_ID	Function_description	E-value
CP029649.1\|AWQ66432.1\|668734_670447_-\|PHP-domain-protein	gnl\|CDD\|236311	PRK08609, PRK08609, DNA polymerase/3'-5' exonuclease PolX.	0
CP029649.1\|AWQ66368.1\|682081_682765_-\|heme-uptake-protein-IsdC	gnl\|CDD\|274705	TIGR03656, IsdC, heme uptake protein IsdC. Isd proteins are iron-regulated surface proteins found in Bacillus, Staphylococcus and Listeria species and are responsible for heme scavenging from hemoproteins. The IsdC protein consists of an N-terminal hydrophobic signal sequence, a central NEAT (NEAr Transporter, pfam05031) domain, which confers the ability to bind heme, and a C-terminal SrtB processing signal which targets the protein to the cell wall. IsdC is believed to make a direct contact with, and transfer heme to, the heme-binding component (IsdE) of an ABC transporter in the cytoplasmic membrane, and to receive heme from other NEAT-containing heme-binding proteins also localized in the cell wall.	2.0626e-97
CP029649.1\|AWQ66177.1\|665889_666204_-\|thioredoxin	gnl\|CDD\|200072	TIGR01068, Thioredoxin-like_protein_slr0233, thioredoxin. Several proteins, such as protein disulfide isomerase, have two or more copies of a domain closely related to thioredoxin. This model is designed to recognize authentic thioredoxin, a small protein that should be hit exactly once by this model. Any protein that hits once with a score greater than the second (per domain) trusted cutoff may be taken as thioredoxin. [Energy metabolism, Electron transport].	3.26685e-48
CP029649.1\|AWQ67739.1\|661028_662795_-\|succinate-dehydrogenase/fumarate-reductase,-flavoprotein-subunit	gnl\|CDD\|236319	PRK08641, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	0
CP029649.1\|AWQ65230.1\|666376_668725_-\|mutS2-protein	gnl\|CDD\|234750	PRK00409, PRK00409, recombination and DNA strand exchange inhibitor protein; Reviewed.	0
CP029649.1\|AWQ66656.1\|675452_676511_-\|phenylalanine--tRNA-ligase,-alpha-subunit	gnl\|CDD\|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
CP029649.1\|AWQ66499.1\|678356_679091_-\|sortase,-SrtB-family	gnl\|CDD\|226898	COG4509, COG4509, Uncharacterized protein conserved in bacteria [Function unknown].	2.78558e-128
CP029649.1\|AWQ66939.1\|671041_671308_-\|cell-division-ZapA-family-protein	gnl\|CDD\|172616	PRK14126, PRK14126, cell division protein ZapA; Provisional.	1.04877e-21
CP029649.1\|AWQ66492.1\|673050_675453_-\|phenylalanine--tRNA-ligase,-beta-subunit	gnl\|CDD\|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
CP029649.1\|AWQ66077.1\|680130_680877_-\|heme-ABC-transporter,-heme-binding-protein-isdE	gnl\|CDD\|274706	TIGR03659, heme_ABC_transporter_heme-binding_protein_isdE, heme ABC transporter, heme-binding protein isdE. This family of ABC substrate-binding proteins is observed primarily in close proximity with proteins localized to the cell wall and bearing the NEAT (NEAr Transporter, pfam05031) heme-binding domain. IsdE has been shown to bind heme and is involved in the process of scavenging heme for the purpose of obtaining iron.	1.10814e-137
CP029649.1\|AWQ65808.1\|659177_659978_-\|glutamate-racemase	gnl\|CDD\|234851	PRK00865, PRK00865, glutamate racemase; Provisional.	2.38427e-134
CP029649.1\|AWQ65155.1\|670519_671041_-\|colicin-V-production-family-protein	gnl\|CDD\|224205	COG1286, CvpA, Uncharacterized membrane protein, required for colicin V production [General function prediction only].	4.13485e-29
CP029649.1\|AWQ67069.1\|662846_663461_-\|succinate-dehydrogenase,-cytochrome-b556-subunit	gnl\|CDD\|239577	cd03497, SQR_TypeB_1_TM, Succinate:quinone oxidoreductase (SQR) Type B subfamily 1, transmembrane subunit; composed of proteins similar to Bacillus subtilis SQR. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Bacillus subtilis SQR reduces low potential quinones such as menaquinone. SQR is also called succinate dehydrogenase (Sdh) or Complex II and is part of the citric acid cycle and the aerobic respiratory chain. SQR is composed of a flavoprotein catalytic subunit, an iron-sulfur protein and one or two hydrophobic transmembrane subunits. Members of this subfamily are classified as Type B as they contain one transmembrane subunit and two heme groups. The heme and quinone binding sites reside on the transmembrane subunit. The transmembrane subunit of Bacillus subtilis SQR is also called Sdh cytochrome b558 subunit. The structural arrangement allows efficient electron transfer between the catalytic subunit, through iron-sulfur centers, and the transmembrane subunit containing the electron acceptor (quinone). The reversible reduction of quinone is an essential feature of respiration, allowing transfer of electrons between respiratory complexes.	2.37018e-87
CP029649.1\|AWQ67653.1\|679152_680118_-\|fecCD-transport-family-protein	gnl\|CDD\|223682	COG0609, FepD, ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism].	1.20946e-60
CP029649.1\|AWQ66536.1\|676890_677631_-\|spoU-rRNA-Methylase-family-protein	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	2.00285e-77
CP029649.1\|AWQ65833.1\|678014_678338_-\|antibiotic-biosynthesis-monooxygenase-family-protein	gnl\|CDD\|139480	PRK13312, PRK13312, staphylobilin-forming heme oxygenase IsdG.	3.35893e-67
CP029649.1\|AWQ67398.1\|663784_665566_-\|excinuclease-ABC-subunit-C	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
CP029649.1\|AWQ65431.1\|682973_684026_+\|iron-regulated-surface-determinant-protein-A	gnl\|CDD\|227676	COG5386, COG5386, Cell surface protein [Cell envelope biogenesis, outer membrane].	3.30621e-123
CP029649.1\|AWQ67187.1\|660213_661029_-\|succinate-dehydrogenase-and-fumarate-reductase-iron-sulfur-family-protein	gnl\|CDD\|181515	PRK08640, sdhB, succinate dehydrogenase iron-sulfur subunit; Reviewed.	0

>CP029649.1|AWQ66939.1|671041_671308_-|cell-division-ZapA-family-protein
MAQFKNKVNVSINDQLFTIVGEDNPEHIRYVAHLVDDKIKELGYKAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQIHKLQQREQ
>CP029649.1|AWQ65155.1|670519_671041_-|colicin-V-production-family-protein
MVIDFIIIIFFVYFVIVGFRRGFWLSMIHLSATIVSLWIASQFYKSIVERLIVFIPYPKTTAFNTTFAFHFNHLQNRFEAIVAFLMITLFCKFILYLIIVTFDKIIAYQNIHIFSRAMGMIVGVFMTIIVLHFTLYLLALYPNEALQHQLKISIVSHSLIFHIPYLSAFTINL
>CP029649.1|AWQ66432.1|668734_670447_-|PHP-domain-protein
MTKKDVIKLLEQIATYMELKGENTFKISAYRKAAQSLELDERPLDEISDVTELKGIGKGVAEVINDYRETGESQYLQQLQEEVPEGLIPLLKIQGLGSKKIAKLYKELNIVDKASLQVACENGKVSELSGFAKKTEQNILEAVKQLGAKKDRYPIDQMRRLNQEIIDYIDTLNYIDQYSSAGSFRRFKEMSKDLDFIISTDNPKAVQQQLLNIPNKVKEVAVGNTKVSLELAYDDETIGVDFRLIEPSAFYHTLQHFTGSKEHNIRIRQLAKARDEKVSEYGIEQADGTLIQYDSEAKIYEHFNVNFIPPAMREDGSEFDKDLSNIITIDDINGDIHMHTTYSDGAFSIRDMVEANIAKGYKFMVITDHSQSLRVANGLQVERLLRQNEEIKALDKEYSEIDIYSGTEMDILPDGSLDYDDEILAQLDYVIGAIHQSFNQSEEQIMERLANACRNPYVRHIAHPTGRIIGRRDGYKPNIEQLMALAEETNTVLEINANPHRLDLNADIVRKYPNVKLTINTDAHHTNHLDFMNYGVATAQKGFVTKDRVINALSREAFKDFIENNIKLKK
>CP029649.1|AWQ65230.1|666376_668725_-|mutS2-protein
MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRSKISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVANTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNIVEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK
>CP029649.1|AWQ66177.1|665889_666204_-|thioredoxin
MAIVKVTDADFDSKVESGVQLVDFWATWCGPCKMIAPVLEELAADYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDKHL
>CP029649.1|AWQ67398.1|663784_665566_-|excinuclease-ABC-subunit-C
MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRLRSYFTGAHDAKTTRLVGEIRRFEFIVTSSETESLLLELNLIKQYQPRYNILLKDDKSYPFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDKLCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDFERAKEYRDLIQHIQNLTNKQKIMSSDKTIRDVFGYCVDKGWMCIQVFFIRQGNMIKRDTTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMIQSVVDTKIVQPARGPKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNIQGVDPVSAMVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLPDLIIVDGGKGHMNGVIDVLQNELGLDIPVAGLQKNDKHQTSELLYGASAEIVPLKKNSQAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIDGIGNKRKTLLLRSFGSIKKMKEATLEDFKNIGIPENVAKNLHEQLHK
>CP029649.1|AWQ67069.1|662846_663461_-|succinate-dehydrogenase,-cytochrome-b556-subunit
MAQSKNEFYLRRIHSLLGIIPIGAFLVVHLLVNHQATQGAEAFNKASNFMESLPFLIIVEFLFIYIPLLYHGLFGIHIAFTAKENVGHYSIFRNWMFFFQRVSGILTFIFIGIHLWQTRLQKAFYGKEVNYDLMHETLQHPGWAIFYIICIIAVVFHFANGLWSFLVTWGGLQSPKSQRVFTWVSLIVFLVISYIGVTAIIAFM
>CP029649.1|AWQ67739.1|661028_662795_-|succinate-dehydrogenase/fumarate-reductase,-flavoprotein-subunit
MAEKHLIVVGGGLAGLMSTIKAAEKGAHVDLFSVVPVKRSHSVCAQGGINGAVNTKGEGDSPWIHFDDTVYGGDFLANQPPVKAMTEAAPKIIHLLDRMGVMFNRTNEGLLDFRRFGGTLHHRTAYAGATTGQQLLYALDEQVRAFEVDGLVTKYEGWEFLGIVKGDDDSARGIVAQNMTTAEIETFGSDAVIMATGGPGIIFGKTTNSMINTGSAASIVYQQGAIYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRIWTYKDGKPWYFLEEKYPDYGNLVPRDIATREIFDVCINQKLGINGENMVYLDLSHKDPHELDVKLGGIIEIYEKFTGDDPRKVPMKIFPAVHYSMGGLYVDYDQMTNIKGLFAAGECDFSQHGGNRLGANSLLSAIYGGTVAGPNAIDYISNIDRSYTDMDESIFEKRKAEEQERFDKLLAMRGTENAYKLHRELGEIMTANVTVVRENEKLLETDKKIVELMKRYEDIDMEDTQTWSNQAVFFTRQLWNMLVLARVITIGAYNRNESRGAHYKPEFPERNDEEWLKTTMASFQGAFEKPQFTYDDVDVSLIPPRKRDYTSKSKGGKK
>CP029649.1|AWQ67187.1|660213_661029_-|succinate-dehydrogenase-and-fumarate-reductase-iron-sulfur-family-protein
MTEQSVKNTPQHETQSKPKQKTVKLIIKRQDTSDSKPYEETFEIPYRENLNVIACLMEIRRNPVNIKGEKTTPVVWDMNCLEEVCGACSMVINGRARQSCSAIVDQLEQPIRLEPMNTFPVIRDLQVDRSRMFDNLKRMKAWIPIDGTYDLGPGPRMPEKKRQTAYELSKCMTCGVCLEVCPNVTENNKFVGAQAISQVRLFNLHPTGSMTKDERLNALMGTGGLQQCGNSQNCVNACPKGIPLTTSIAAMNRETTFHMFKSFFGSDHEVE
>CP029649.1|AWQ65808.1|659177_659978_-|glutamate-racemase
MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPRPGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTAIMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTITSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSALLTFSNEHASYTEHPDHRFFATGDPTHITNIIKEWLNLSVNVERISVND
>CP029649.1|AWQ66492.1|673050_675453_-|phenylalanine--tRNA-ligase,-beta-subunit
MLISNEWLKEYVTIDDSVSNLAERITRTGIEVDDLIDYTKDIKNLVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCGAPNVDAGQYVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNYIPKSFESGIYVFSEAQVPGTDALQALYLDDQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPDTTSNELELSANNELTVTIENEDKVPYYSARVVHDVTIEPSPIWMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDAIGSQQIVVRQANEGEKMTTLDGTERELLTSDIVITNGQTPIALAGVMGGDFSEVKEQTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYANGKVLKDRVSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDVITVQVPSRRKDITIKEDLIEEVARIYGYDDIPSTLPVFEKVTSGQLTDRQYKTRMVKEVLEGAGLDQAITYSLVSKEDATAFSMQQRQTIDLLMPMSEAHASLRQSLLPHLIEAASYNVARKNKDVKLFEIGNVFFANGEGELPDQVEYLSGILTGDYVVNQWQGKKETVDFYLAKGIVDRVSEKLNLEFSYRRADIDGLHPGRTAEILLENKVVGFIGELHPTLAADNDLKRTYVFELNFDALMAVSVGYINYQPIPRFPGMSRDIALEVDQNIPAADLLSTIHAHGGNILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIEHGAVIR
>CP029649.1|AWQ66656.1|675452_676511_-|phenylalanine--tRNA-ligase,-alpha-subunit
MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGLMKLMKDLPNEEKPAFGQKVNELRQTIQNELDERQQMLVKEKLNKQLAEETIDVSLPGRHIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDSFYITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNVKMSDLKGTLELLAKKLFGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIAMLKYGIEDIRHFYTNDVRFLDQFKAVEDRGDM
>CP029649.1|AWQ66536.1|676890_677631_-|spoU-rRNA-Methylase-family-protein
MEQITSAQNNRIKQANKLKKKRERDKTGLALIEGVHLIEEAYQSGIVITQLFAIEPARLDQQIIAYAQEVFEINMKVAESLSGTVTPQGFFAIIEKPHYDISKAQQVLLIDRVQDPGNLGTLIRTADAAGMDAVIMEKGTTDPYQDKVLRASQGSVFHLPVMIQDLDTFITQFNGPVYGTALENAVAYKEVTSSDSFALLLGNEGEGVNPELLAHTTQNLIIPIYGKAESLNVAIAGSILLYHLKG
>CP029649.1|AWQ65833.1|678014_678338_-|antibiotic-biosynthesis-monooxygenase-family-protein
MKFMAENRLTLTKGTAKDIIERFYTRHGIETLEGFDGMFVTQTLEQEDFDEVKILTVWKSKQAFTDWLKSDVFKAAHKHVRSKNEDESSPIINNKVITYDIGYSYMK
>CP029649.1|AWQ66499.1|678356_679091_-|sortase,-SrtB-family
MRMKRFLTIVQILLVVIIIIFGYKIVQTYIEDKQERANYEKLQQKFQMLMSKHQAHVRPQFESLEKINKDIVGWIKLSGTSLNYPVLQGKTNHDYLNLDFEREHRRKGSIFMDFRNELKNLNHNTILYGHHVGDNTMFDVLEDYLKQSFYEKHKIIEFDNKYGKYQLQVFSAYKTTTKDNYIRTDFENDQDYQQFLDETKRKSVINSDVNVTVKDRIMTLSTCEDAYSETTKRIVVVAKIIKVS
>CP029649.1|AWQ67653.1|679152_680118_-|fecCD-transport-family-protein
MIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLFTKFTTGSNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRALCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLEILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSPKLNLLNLDDIQARSIGFNIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGAWLLLVADLLGRVIQPPLEIPANAILMIVGGPMLICLICQSQRNRI
>CP029649.1|AWQ66077.1|680130_680877_-|heme-ABC-transporter,-heme-binding-protein-isdE
MTLDKLDLPIVGKPTSYKTLPNRYKDVPEIGQPMEPNVEAVKKLKPTHVLSVSTIKDEMQPFYKQLNMKGYFYDFDSLKGMQKSITQLGDQFNRKAQAKELNDHLNSVKQKIENKAAKQKKHPKVLILMGVPGSYLVATDKSYIGDLVKIAGGENVIKVKDRQYISSNTENLLNINPDIILRLPHGMPEEVKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPFGITANVDADKAMTQLYDLFYKDKK
>CP029649.1|AWQ65784.1|681005_682082_-|iron-(Fe+3)-ABC-superfamily-ATP-binding-cassette-transporter
MRNVKQIATKSIIAIISLGILTYTTMIGSVLADEIKYPSAKFNQPEAKDKTELTTSIFDEKIKENKALELLIFNQENKNVTEEQKLVDEKAQLISDMTGKIYLQVKLKGQIDKEQLVFQNDKNEEFPFVIKDEKDDTIVRILIEQHMDKINMHVKTLAEKKNLDNKEMVYSIHFKEKKVQHDDAKEVPSKHQNQENNQDQLKKDIDDKKDSQKSDTKERRTSLFTEKGLNDIPVQKDKVQQDSNKKIENERPKASGTLKVENSPPTIKKVENNHKEQPKHKDEKSKKEKKKVVEKEKALPAFNRDDDSKNSSQLSSDIKELDEPNHKKQYILFAAGIVLATILLISAHLYSRKRGNQV
>CP029649.1|AWQ66368.1|682081_682765_-|heme-uptake-protein-IsdC
MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTNDTSIANDYFNKPAKYIKKNGKLYVQITVNHSHWITGMSIEGHKENIISKNTAKDERTSEFEVSKLNGKIDGKIDVYIDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKNSASGSDKGSDGTTTGQSESNSSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFVRKKSKGNVE
>CP029649.1|AWQ65431.1|682973_684026_+|iron-regulated-surface-determinant-protein-A
MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQVNAATEATNATNNQSTQVSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYYFQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIVVPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEKVKPTVTTTSKVEDNHSTKVVSTDTTKDQTKTQTAHTVKTAQTAQEQNKVQTPVKDVATAKSESNNQAVSDNKSQQTNKVTKHNETPKQASKAKELPKTGLTSVDNFISTVAFATLALLGSLSLLLFKRKESK

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Crispr_ID: CP029649_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029649_3

869975-870053

Orphan

Consensus_repeat	Method
CCAGCCTCTGTGTTGGGGCCCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029649_3

>merge|CP029649|3|869975-870053|CRISPRCasFinder
CCAGCCTCTGTGTTGGGGCCCCGCCAACTTGCACACTATTGTAAGCTGACTTTCCACCAGCCTCTGTGTTGGGGCCCCG

>CP029649|3|3|869975-870053|CRISPRCasFinder
CCAGCCTCTGTGTTGGGGCCCCG	CCAACTTGCACACTATTGTAAGCTGACTTTCCA
CCAGCCTCTGTGTTGGGGCCCCG

Protein	Signature genes	Signature genes Name	Protein_function
CP029649.1\|AWQ65341.1\|875966_876350_+\|kinase-associated-B-family-protein	unknown	unknown	gnl\|CDD\|378054
CP029649.1\|AWQ66412.1\|867176_868556_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179143
CP029649.1\|AWQ65695.1\|868797_869727_+\|glycerophosphoryl-diester-phosphodiesterase-family-protein	unknown	unknown	gnl\|CDD\|176543
CP029649.1\|AWQ66187.1\|853922_854825_-\|fumarylacetoacetate-(FAA)-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
CP029649.1\|AWQ67595.1\|864300_865632_-\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|184504
CP029649.1\|AWQ66420.1\|862871_863396_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP029649.1\|AWQ65175.1\|875309_875903_-\|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase/CLD-family-protein	unknown	unknown	gnl\|CDD\|238908
CP029649.1\|AWQ66113.1\|873028_874156_-\|flavin-oxidoreductase-/-NADH-oxidase-family-protein	unknown	unknown	gnl\|CDD\|240086
CP029649.1\|AWQ66369.1\|854990_858644_-\|helicase-exonuclease-AddAB,-AddA-subunit	unknown	unknown	gnl\|CDD\|274299
CP029649.1\|AWQ66029.1\|878878_879307_+\|na(+)/H(+)-antiporter-subunit-B	unknown	unknown	gnl\|CDD\|183602
CP029649.1\|AWQ65902.1\|879393_879648_+\|na(+)/H(+)-antiporter-subunit-C	unknown	unknown	gnl\|CDD\|181497
CP029649.1\|AWQ67741.1\|863400_863976_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223475
CP029649.1\|AWQ66803.1\|879640_881137_+\|na(+)/H(+)-antiporter-subunit-D	unknown	unknown	gnl\|CDD\|181085
CP029649.1\|AWQ66563.1\|862280_862856_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
CP029649.1\|AWQ65187.1\|871530_872721_-\|ornithine--oxo-acid-transaminase	unknown	unknown	gnl\|CDD\|179736
CP029649.1\|AWQ65424.1\|876480_878886_+\|na(+)/H(+)-antiporter-subunit-A1	unknown	unknown	gnl\|CDD\|237155
CP029649.1\|AWQ66212.1\|865981_867187_+\|argininosuccinate-synthase	unknown	unknown	gnl\|CDD\|234785
CP029649.1\|AWQ65807.1\|870177_871422_-\|NAD-specific-glutamate-dehydrogenase	unknown	unknown	gnl\|CDD\|223411
CP029649.1\|AWQ66231.1\|874517_874895_-\|S1-RNA-binding-domain-protein	unknown	unknown	gnl\|CDD\|224023
CP029649.1\|AWQ65420.1\|858644_862121_-\|helicase-exonuclease-AddAB,-AddB-subunit	unknown	unknown	gnl\|CDD\|213736

Protein	Function_ID	Function_description	E-value
CP029649.1\|AWQ65341.1\|875966_876350_+\|kinase-associated-B-family-protein	gnl\|CDD\|378054	pfam08810, KapB, Kinase associated protein B. This bacterial protein forms an anti-parallel beta sheet with an extending alpha helical region.	8.96507e-53
CP029649.1\|AWQ66412.1\|867176_868556_+\|argininosuccinate-lyase	gnl\|CDD\|179143	PRK00855, PRK00855, argininosuccinate lyase; Provisional.	0
CP029649.1\|AWQ65695.1\|868797_869727_+\|glycerophosphoryl-diester-phosphodiesterase-family-protein	gnl\|CDD\|176543	cd08601, GDPD_SaGlpQ_like, Glycerophosphodiester phosphodiesterase domain of Staphylococcus aureus and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in uncharacterized glycerophosphodiester phosphodiesterase (GP-GDE, EC 3.1.4.46) from Staphylococcus aureus, Bacillus subtilis and similar proteins. Members in this family show very high sequence similarity to Escherichia coli periplasmic phosphodiesterase GlpQ, which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols.	5.11302e-151
CP029649.1\|AWQ66187.1\|853922_854825_-\|fumarylacetoacetate-(FAA)-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	1.74159e-87
CP029649.1\|AWQ67595.1\|864300_865632_-\|glucose-6-phosphate-isomerase	gnl\|CDD\|184504	PRK14097, pgi, glucose-6-phosphate isomerase; Provisional.	0
CP029649.1\|AWQ66420.1\|862871_863396_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	9.64837e-49
CP029649.1\|AWQ65175.1\|875309_875903_-\|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase/CLD-family-protein	gnl\|CDD\|238908	cd01927, cyclophilin_WD40, cyclophilin_WD40: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) having a WD40 domain. This group consists of several hypothetical and putative eukaryotic and bacterial proteins which have a cyclophilin domain and a WD40 domain. Function of the protein is not known.	3.93388e-65
CP029649.1\|AWQ66113.1\|873028_874156_-\|flavin-oxidoreductase-/-NADH-oxidase-family-protein	gnl\|CDD\|240086	cd04735, OYE_like_4_FMN, Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Other members of OYE family include trimethylamine dehydrogenase, 2,4-dienoyl-CoA reductase, enoate reductase, pentaerythriol tetranitrate reductase, xenobiotic reductase, and morphinone reductase.	0
CP029649.1\|AWQ66369.1\|854990_858644_-\|helicase-exonuclease-AddAB,-AddA-subunit	gnl\|CDD\|274299	TIGR02785, ATP-dependent_helicase/nuclease_subunit_A, helicase-exonuclease AddAB, AddA subunit, Firmicutes type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the Firmicutes (as modeled here) and the alphaproteobacteria, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
CP029649.1\|AWQ66029.1\|878878_879307_+\|na(+)/H(+)-antiporter-subunit-B	gnl\|CDD\|183602	PRK12573, PRK12573, Na(+)/H(+) antiporter subunit B.	9.17513e-61
CP029649.1\|AWQ65902.1\|879393_879648_+\|na(+)/H(+)-antiporter-subunit-C	gnl\|CDD\|181497	PRK08600, PRK08600, putative monovalent cation/H+ antiporter subunit C; Reviewed.	7.96732e-49
CP029649.1\|AWQ67741.1\|863400_863976_-\|hypothetical-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.01759e-40
CP029649.1\|AWQ66803.1\|879640_881137_+\|na(+)/H(+)-antiporter-subunit-D	gnl\|CDD\|181085	PRK07691, PRK07691, putative monovalent cation/H+ antiporter subunit D; Reviewed.	0
CP029649.1\|AWQ66563.1\|862280_862856_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	3.65162e-54
CP029649.1\|AWQ65187.1\|871530_872721_-\|ornithine--oxo-acid-transaminase	gnl\|CDD\|179736	PRK04073, rocD, ornithine--oxo-acid transaminase; Provisional.	0
CP029649.1\|AWQ65424.1\|876480_878886_+\|na(+)/H(+)-antiporter-subunit-A1	gnl\|CDD\|237155	PRK12645, PRK12645, monovalent cation/H+ antiporter subunit A; Reviewed.	0
CP029649.1\|AWQ66212.1\|865981_867187_+\|argininosuccinate-synthase	gnl\|CDD\|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
CP029649.1\|AWQ65807.1\|870177_871422_-\|NAD-specific-glutamate-dehydrogenase	gnl\|CDD\|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
CP029649.1\|AWQ66231.1\|874517_874895_-\|S1-RNA-binding-domain-protein	gnl\|CDD\|224023	COG1098, VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) [Translation, ribosomal structure and biogenesis].	3.22125e-44
CP029649.1\|AWQ65420.1\|858644_862121_-\|helicase-exonuclease-AddAB,-AddB-subunit	gnl\|CDD\|213736	TIGR02773, ATP-dependent_helicase/deoxyribonuclease_subunit_B, helicase-exonuclease AddAB, AddB subunit. DNA repair is accomplished by several different systems in prokaryotes. Recombinational repair of double-stranded DNA breaks involves the RecBCD pathway in some lineages, and AddAB (also called RexAB) in other. The AddA protein is conserved between the firmicutes and the alphaproteobacteria, while the partner protein is not. Nevertheless, the partner is designated AddB in both systems. This model describes the AddB protein as found Bacillus subtilis and related species. Although the RexB protein of Streptococcus and Lactococcus is considered to be orthologous, functionally equivalent, and merely named differently, all members of this protein family have a P-loop nucleotide binding motif GxxGxGK[ST] at the N-terminus, unlike RexB proteins, and a CxxCxxxxxC motif at the C-terminus, both of which may be relevant to function. [DNA metabolism, DNA replication, recombination, and repair].	0

>CP029649.1|AWQ65695.1|868797_869727_+|glycerophosphoryl-diester-phosphodiesterase-family-protein
MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQWHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMHDETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERYGPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHRQNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHPYTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK
>CP029649.1|AWQ66412.1|867176_868556_+|argininosuccinate-lyase
MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHATMLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGGKLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQRAQPISFAHHIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLNFGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFSTGSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVHTIKGSLRIFEGMIQTMTINKERLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKIVLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQLDVAKQLLSQ
>CP029649.1|AWQ66212.1|865981_867187_+|argininosuccinate-synthase
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDAADEIILTFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
>CP029649.1|AWQ67595.1|864300_865632_-|glucose-6-phosphate-isomerase
MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDFLGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNSNEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEERYGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSVLTAVGLLPIATAGINIEAMMIGAAKAREELSSDKLEDNIAYQYATIRNILYAKGYTTEMLINYEPSMQYFNEWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDITIEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVVYFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL
>CP029649.1|AWQ67741.1|863400_863976_-|hypothetical-protein
MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINIQAYGPILGILISWLGLISGTFTVYLICKRLVNTERMQRIKQRTAVQRLISFIDRQGLIPLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTHPLRGILMLVVLVVFWIVGKKLEQHFMGSKKE
>CP029649.1|AWQ66420.1|862871_863396_-|signal-peptidase-I
MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPSLNKGDRVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDASYAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDHDNNQHDSRQFGLIDKKDIIGNISLRYYPFSKWTIQFKS
>CP029649.1|AWQ66563.1|862280_862856_-|signal-peptidase-I
MKKELLEWIISIAIALVIFAIIGKFIVTPYTIKGESMDPTLKDGERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQDEPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGLIDEDQIVGKVSFRFWPFSEFKHNFNPENTKN
>CP029649.1|AWQ65420.1|858644_862121_-|helicase-exonuclease-AddAB,-AddB-subunit
MTLHAYLGRAGTGKSTKMLTETKQKMKADPLGDPIILIAPTQSTFQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQEQQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKIEDIALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKGLIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFKQLYRFNNQDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIAILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLRLLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTEDERNTFEQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERDELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDETMSMERFLEVFDIGLEQLEFVMIPQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVELSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLEITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLYDEIVADSWLDAYQVIRDSDHLNQGLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNERTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEEILPKVQFNLLNSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLTTTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYMDIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLVNADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFIETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQNININDEFGGEQ
>CP029649.1|AWQ66369.1|854990_858644_-|helicase-exonuclease-AddAB,-AddA-subunit
MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQAQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDLSKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTDHEFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYRQHFQEILVDEYQDTNRVQEKILSCIKTGDEHNGNLFMVGDVKQSIYKFRQADPSLFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVKYDEAAQLYYGAPYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRSATYKDIVILERSFGQAHNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFENSSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVYVALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQSASIPDDLKFEKDIAQVEDSSRPNVNISIIYFEDVSTETILDNNEYRSVNQLETMQNGNEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFSTYERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADAKKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMIDLIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVKGYLYFFKFGTLQL
>CP029649.1|AWQ66187.1|853922_854825_-|fumarylacetoacetate-(FAA)-hydrolase-family-protein
MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTLLAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNYKDHANELNHEVERLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKIPKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENVNIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPKFLQPGDEVKVTIDNIGTLTTYIAK
>CP029649.1|AWQ65807.1|870177_871422_-|NAD-specific-glutamate-dehydrogenase
MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIPVRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPYGGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDEYSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQGFGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETISNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILLVPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDMRLAAYIIGIKRTAEAARYRGWA
>CP029649.1|AWQ65187.1|871530_872721_-|ornithine--oxo-acid-transaminase
MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMDMLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALPMNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRGYGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDEHNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDVFTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEVRGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIRHVFQ
>CP029649.1|AWQ66113.1|873028_874156_-|flavin-oxidoreductase-/-NADH-oxidase-family-protein
MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVELPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKALVQIHHGGAQALPELTPGGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEATRRAIEAGFDGVEIHGANHYLIHQFVSPYYNRRNDVWVNQYKFPVAVIEEVLKAKEAYGNKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAGQERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFVEKIKDGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK
>CP029649.1|AWQ66231.1|874517_874895_-|S1-RNA-binding-domain-protein
MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYVHNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKYGFQTLKERLPIWIKQSKRAIRND
>CP029649.1|AWQ65175.1|875309_875903_-|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase/CLD-family-protein
MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFVTHAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALSMANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVFGQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE
>CP029649.1|AWQ65341.1|875966_876350_+|kinase-associated-B-family-protein
MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNPTETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTKHAEMSLASLARLKEDYSLQYKENFK
>CP029649.1|AWQ65424.1|876480_878886_+|na(+)/H(+)-antiporter-subunit-A1
MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIYMLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYLSKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIYGAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIGAFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWVWTVTLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYAAAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITALSMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSIKFIMHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSINHTVIDDVEFHMFHGLTPAFISTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNRSANVIPNYSEKMTNSYVTDYSRNNLVIIFGALILLTFVTIFSVPFNINFKDVSPIRIFEVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESISTALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFYQEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVKNHE
>CP029649.1|AWQ66029.1|878878_879307_+|na(+)/H(+)-antiporter-subunit-B
MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGLLFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFDIPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE
>CP029649.1|AWQ65902.1|879393_879648_+|na(+)/H(+)-antiporter-subunit-C
MGTTLLTHAANLFLITMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDNVESMKGVPEDD
>CP029649.1|AWQ66803.1|879640_881137_+|na(+)/H(+)-antiporter-subunit-D
MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLVAAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTIGIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQETIKYLLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIFVFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSHYVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYTLHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSGFYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVKYLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK

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Crispr_ID: CP029649_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029649_4

966475-966552

Unclear

Consensus_repeat	Method
TGGCGGGGCCCCAACATAAAGAA	CRISPRCasFinder

1 spacers

cas3

The CRISPR arrays of CP029649_4

>merge|CP029649|4|966475-966552|CRISPRCasFinder
TGGCGGGGCCCCAACATAAAGAATTTCGAAAAGAAATTCTACAAACAATGCAAGTTGGCGGGGCCCCAACATAAAGAA

>CP029649|4|4|966475-966552|CRISPRCasFinder
TGGCGGGGCCCCAACATAAAGAA	TTTCGAAAAGAAATTCTACAAACAATGCAAGT
TGGCGGGGCCCCAACATAAAGAA

Protein	Signature genes	Signature genes Name	Protein_function
CP029649.1\|AWQ66575.1\|969694_971680_-\|excinuclease-ABC-subunit-B	unknown	unknown	gnl\|CDD\|235395
CP029649.1\|AWQ66783.1\|962517_963957_-\|tetratricopeptide-repeat-family-protein	unknown	unknown	gnl\|CDD\|276808
CP029649.1\|AWQ65142.1\|978623_979196_-\|ribosomal-subunit-interface-protein	unknown	unknown	gnl\|CDD\|224461
CP029649.1\|AWQ67385.1\|979923_981006_-\|type-III-restriction-enzyme,-res-subunit	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|226583
CP029649.1\|AWQ67089.1\|966840_969687_-\|excinuclease-ABC-subunit-A	unknown	unknown	gnl\|CDD\|234734
CP029649.1\|AWQ65370.1\|972181_972832_-\|HD-containing-hydrolase-like-enzyme-family-protein	unknown	unknown	gnl\|CDD\|378993
CP029649.1\|AWQ66904.1\|957558_958503_-\|sporulation-Regulator-WhiA-C-terminal-domain-protein	unknown	unknown	gnl\|CDD\|273194
CP029649.1\|AWQ66178.1\|973005_973845_-\|staphyloxanthin-biosynthesis-protein,-putative	unknown	unknown	gnl\|CDD\|226451
CP029649.1\|AWQ65186.1\|974253_975246_-\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
CP029649.1\|AWQ65265.1\|979256_979931_-\|putative-amidophosphoribosyltransferase,-ComFC	unknown	unknown	gnl\|CDD\|223970
CP029649.1\|AWQ66182.1\|959605_960517_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224574
CP029649.1\|AWQ65590.1\|965302_966235_-\|HPr(Ser)-kinase/phosphatase	unknown	unknown	gnl\|CDD\|235459
CP029649.1\|AWQ66598.1\|955262_956165_+\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|224015
CP029649.1\|AWQ65316.1\|963964_964246_-\|bacterial-transferase-hexapeptide-family-protein	unknown	unknown	gnl\|CDD\|100047
CP029649.1\|AWQ67015.1\|956407_956995_-\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
CP029649.1\|AWQ66875.1\|975678_978210_-\|preprotein-translocase,-SecA-subunit	unknown	unknown	gnl\|CDD\|237259
CP029649.1\|AWQ67168.1\|958613_959609_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|211689
CP029649.1\|AWQ65775.1\|961515_962451_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
CP029649.1\|AWQ67149.1\|964457_965297_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
CP029649.1\|AWQ67345.1\|971948_972185_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227234

Protein	Function_ID	Function_description	E-value
CP029649.1\|AWQ66575.1\|969694_971680_-\|excinuclease-ABC-subunit-B	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
CP029649.1\|AWQ66783.1\|962517_963957_-\|tetratricopeptide-repeat-family-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
CP029649.1\|AWQ65142.1\|978623_979196_-\|ribosomal-subunit-interface-protein	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
CP029649.1\|AWQ67385.1\|979923_981006_-\|type-III-restriction-enzyme,-res-subunit	gnl\|CDD\|226583	COG4098, comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair].	1.55868e-179
CP029649.1\|AWQ67089.1\|966840_969687_-\|excinuclease-ABC-subunit-A	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
CP029649.1\|AWQ65370.1\|972181_972832_-\|HD-containing-hydrolase-like-enzyme-family-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
CP029649.1\|AWQ66904.1\|957558_958503_-\|sporulation-Regulator-WhiA-C-terminal-domain-protein	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
CP029649.1\|AWQ66178.1\|973005_973845_-\|staphyloxanthin-biosynthesis-protein,-putative	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.82721e-42
CP029649.1\|AWQ65186.1\|974253_975246_-\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
CP029649.1\|AWQ65265.1\|979256_979931_-\|putative-amidophosphoribosyltransferase,-ComFC	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	1.0058e-51
CP029649.1\|AWQ66182.1\|959605_960517_-\|hypothetical-protein	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
CP029649.1\|AWQ65590.1\|965302_966235_-\|HPr(Ser)-kinase/phosphatase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
CP029649.1\|AWQ66598.1\|955262_956165_+\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	1.43426e-153
CP029649.1\|AWQ65316.1\|963964_964246_-\|bacterial-transferase-hexapeptide-family-protein	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	6.00673e-25
CP029649.1\|AWQ67015.1\|956407_956995_-\|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
CP029649.1\|AWQ66875.1\|975678_978210_-\|preprotein-translocase,-SecA-subunit	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
CP029649.1\|AWQ67168.1\|958613_959609_-\|hypothetical-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
CP029649.1\|AWQ65775.1\|961515_962451_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	5.91243e-154
CP029649.1\|AWQ67149.1\|964457_965297_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	4.81145e-120
CP029649.1\|AWQ67345.1\|971948_972185_-\|hypothetical-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34

>CP029649.1|AWQ65590.1|965302_966235_-|HPr(Ser)-kinase/phosphatase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>CP029649.1|AWQ67149.1|964457_965297_-|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYVENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>CP029649.1|AWQ65316.1|963964_964246_-|bacterial-transferase-hexapeptide-family-protein
MLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLVGANSIILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>CP029649.1|AWQ66783.1|962517_963957_-|tetratricopeptide-repeat-family-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>CP029649.1|AWQ65775.1|961515_962451_-|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLKDQA
>CP029649.1|AWQ66182.1|959605_960517_-|hypothetical-protein
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>CP029649.1|AWQ67168.1|958613_959609_-|hypothetical-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>CP029649.1|AWQ66904.1|957558_958503_-|sporulation-Regulator-WhiA-C-terminal-domain-protein
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>CP029649.1|AWQ67015.1|956407_956995_-|ATP-dependent-Clp-endopeptidase,-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>CP029649.1|AWQ66598.1|955262_956165_+|NAD-dependent-epimerase/dehydratase-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE
>CP029649.1|AWQ67089.1|966840_969687_-|excinuclease-ABC-subunit-A
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>CP029649.1|AWQ66575.1|969694_971680_-|excinuclease-ABC-subunit-B
MVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYRTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQIRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>CP029649.1|AWQ67345.1|971948_972185_-|hypothetical-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>CP029649.1|AWQ65370.1|972181_972832_-|HD-containing-hydrolase-like-enzyme-family-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>CP029649.1|AWQ66178.1|973005_973845_-|staphyloxanthin-biosynthesis-protein,-putative
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKTPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>CP029649.1|AWQ65186.1|974253_975246_-|peptide-chain-release-factor-2
MAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>CP029649.1|AWQ66875.1|975678_978210_-|preprotein-translocase,-SecA-subunit
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>CP029649.1|AWQ65142.1|978623_979196_-|ribosomal-subunit-interface-protein
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>CP029649.1|AWQ65265.1|979256_979931_-|putative-amidophosphoribosyltransferase,-ComFC
MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKARRCSRCLKHLNQDEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFLKDYYLCELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPKQSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFKVFAFAR
>CP029649.1|AWQ67385.1|979923_981006_-|type-III-restriction-enzyme,-res-subunit
MDNVTRYKITESSQSSSQAYYHLSFELSEQQSYASEHIVRAIRKRQTILLYAVTGAGKTEMMFQGIQYARIQGDNIAIVSPRVDVVVEISKRIKDAFLNEDIDILHQQSRQQFEGHFVVCTVHQLYRFKQHFDTIFIDEVDAFPLSMDKNLQQALKSSSKVEHATIYMTATPPKQLLSEIPHENIIKLPARFHKKSLPVPKYRYFKLNNKKIQKMLYRILQDQINNQRYTLVFFNNIETMIKTFSVYKQKITKLTYVHSEDVFRFEKVEQLRNGHFDVIFTTTILERGFTMANLDVVVIDAHQYTQEALIQIAGRVGRKLECPTGKVLFFHEGVSMNMIQAKKEIQRMNKLALKRGWIDE

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Crispr_ID: CP029649_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029649_5

1383770-1383872

Orphan

Consensus_repeat	Method
CAAATTTAATACTCAATTCATATA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029649_5

>merge|CP029649|5|1383770-1383872|CRISPRCasFinder
CAAATTTAATACTCAATTCATATATAGCTTTGATTTAAAAACTGATTTTTTATAAACCTATAGAACTGTAATTTACTTTCAAATTTAATACTCAATTCATAAA

>CP029649|5|5|1383770-1383872|CRISPRCasFinder
CAAATTTAATACTCAATTCATATA	TAGCTTTGATTTAAAAACTGATTTTTTATAAACCTATAGAACTGTAATTTACTTT
CAAATTTAATACTCAATTCATAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP029649.1\|AWQ67657.1\|1391360_1391987_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380196
CP029649.1\|AWQ66359.1\|1392242_1392626_+\|putative-membrane-protein	unknown	unknown	unknown
CP029649.1\|AWQ67371.1\|1387445_1388015_+\|peroxiredoxin	unknown	unknown	gnl\|CDD\|211789
CP029649.1\|AWQ65825.1\|1381466_1381874_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378584
CP029649.1\|AWQ66799.1\|1379107_1380376_-\|xanthine-permease-family-protein	unknown	unknown	gnl\|CDD\|274468
CP029649.1\|AWQ67209.1\|1386198_1386954_-\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|380322
CP029649.1\|AWQ67631.1\|1380375_1380954_-\|xanthine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181705
CP029649.1\|AWQ66631.1\|1392691_1393273_-\|histidine-phosphatase-super-family-protein	unknown	unknown	gnl\|CDD\|223483
CP029649.1\|AWQ66950.1\|1373747_1373945_-\|helix-turn-helix-family-protein	unknown	unknown	gnl\|CDD\|197775
CP029649.1\|AWQ66037.1\|1384730_1386119_+\|L-cystine-uptake-protein-TcyP	unknown	unknown	gnl\|CDD\|224736
CP029649.1\|AWQ67360.1\|1374807_1375944_+\|phage-integrase-family-protein	unknown	unknown	gnl\|CDD\|271189
CP029649.1\|AWQ67080.1\|1376037_1377579_-\|GMP-synthase	unknown	unknown	gnl\|CDD\|234614
CP029649.1\|AWQ65405.1\|1382796_1383753_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
CP029649.1\|AWQ65846.1\|1388030_1389554_+\|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl\|CDD\|237942
CP029649.1\|AWQ65208.1\|1392055_1392181_-\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ67738.1\|1389668_1391288_+\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ66498.1\|1374088_1374712_+\|helix-turn-helix-family-protein	unknown	unknown	gnl\|CDD\|238045
CP029649.1\|AWQ67619.1\|1382016_1382679_+\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ66310.1\|1377603_1379070_-\|inosine-5'-monophosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235507
CP029649.1\|AWQ66614.1\|1393702_1393954_-\|transglycosylase-associated-family-protein	unknown	unknown	gnl\|CDD\|225170

Protein	Function_ID	Function_description	E-value
CP029649.1\|AWQ67657.1\|1391360_1391987_+\|hypothetical-protein	gnl\|CDD\|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.15385e-71
CP029649.1\|AWQ67371.1\|1387445_1388015_+\|peroxiredoxin	gnl\|CDD\|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
CP029649.1\|AWQ65825.1\|1381466_1381874_+\|hypothetical-protein	gnl\|CDD\|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.17298e-12
CP029649.1\|AWQ66799.1\|1379107_1380376_-\|xanthine-permease-family-protein	gnl\|CDD\|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	5.28569e-170
CP029649.1\|AWQ67209.1\|1386198_1386954_-\|NADPH-dependent-oxidoreductase	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	5.03864e-88
CP029649.1\|AWQ67631.1\|1380375_1380954_-\|xanthine-phosphoribosyltransferase	gnl\|CDD\|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
CP029649.1\|AWQ66631.1\|1392691_1393273_-\|histidine-phosphatase-super-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	1.30018e-49
CP029649.1\|AWQ66950.1\|1373747_1373945_-\|helix-turn-helix-family-protein	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	0.000309287
CP029649.1\|AWQ66037.1\|1384730_1386119_+\|L-cystine-uptake-protein-TcyP	gnl\|CDD\|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
CP029649.1\|AWQ67360.1\|1374807_1375944_+\|phage-integrase-family-protein	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.94703e-50
CP029649.1\|AWQ67080.1\|1376037_1377579_-\|GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
CP029649.1\|AWQ65405.1\|1382796_1383753_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00304381
CP029649.1\|AWQ65846.1\|1388030_1389554_+\|alkyl-hydroperoxide-reductase-subunit-F	gnl\|CDD\|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
CP029649.1\|AWQ66498.1\|1374088_1374712_+\|helix-turn-helix-family-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.00285e-14
CP029649.1\|AWQ66310.1\|1377603_1379070_-\|inosine-5'-monophosphate-dehydrogenase	gnl\|CDD\|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
CP029649.1\|AWQ66614.1\|1393702_1393954_-\|transglycosylase-associated-family-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.89532e-08

>CP029649.1|AWQ65405.1|1382796_1383753_+|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLFGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKVLAESTNKVEKNAVTEDKADSKDSKVAGVTTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNENAAETSNKEATVDADAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>CP029649.1|AWQ67619.1|1382016_1382679_+|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>CP029649.1|AWQ65825.1|1381466_1381874_+|hypothetical-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHKEVQEHNSAYEEIDITHFAEASKGPKA
>CP029649.1|AWQ67631.1|1380375_1380954_-|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>CP029649.1|AWQ66799.1|1379107_1380376_-|xanthine-permease-family-protein
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLIICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>CP029649.1|AWQ66310.1|1377603_1379070_-|inosine-5'-monophosphate-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>CP029649.1|AWQ67080.1|1376037_1377579_-|GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>CP029649.1|AWQ67360.1|1374807_1375944_+|phage-integrase-family-protein
MIKKYKKKDGTTAYMFVAYLGTDPITGKQKRTTRRGFKTEREAKIAEAKLQTEISRNGFLNNDITTFKEVYELWLEQYQNTVRESTYQRVLTLFDTAILEHFKDVPIKKITVPYCQKVINKWNEKYSDIKAIRIYTSNVFKYAVNLKIIADNPFTHTKAPRKKEAQQDASTKYYSSDELKQFLTFVEDDPLYYAIFRTLAFTGFRRGELMALTWNDIDFTKQTISINKTCARGANYKMVIQEPKTKSSHRTISIDDKTANVLKSWRTHQRVESLKYGHNTSDKYQYVFTTVRDNKQLYPEHCNKALNLICEKHNFKRIKVHGFRHTHCSLLFEAGLSIQEVQDRLGHGDIKTTMDIYAHVTEKQRDQVADKFAKYINF
>CP029649.1|AWQ66498.1|1374088_1374712_+|helix-turn-helix-family-protein
MENRIAELRKENNMTLKQLAKELNIRDNTLSQYETGKRNPQMGLLQEIANFFGVSMEYILKATNKRDYPIADSKSAIELLERMENEKGFNYLHISKNTALNLSLWIINNMDYIKEKHPNLLYTASFLVKNTVSENKILQHYSETRIKELQIVDEIDDILLEREFYGASAEQVLEFIHQSERIGHQQTEALMNYIRDLPTEEYDDEDI
>CP029649.1|AWQ66950.1|1373747_1373945_-|helix-turn-helix-family-protein
MFGIDENLSSKLREIRARKNITLQQASKEIGISSKTLSLIENEMLVKVKRTTYEKVTKWIINEVK
>CP029649.1|AWQ66037.1|1384730_1386119_+|L-cystine-uptake-protein-TcyP
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKSAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLVILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNAALTSH
>CP029649.1|AWQ67209.1|1386198_1386954_-|NADPH-dependent-oxidoreductase
MSEHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>CP029649.1|AWQ67371.1|1387445_1388015_+|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>CP029649.1|AWQ65846.1|1388030_1389554_+|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>CP029649.1|AWQ67738.1|1389668_1391288_+|hypothetical-protein
MLDVHFIYPGKLQNACEYFNLSTSKEGFEVTIHALRPENIHKIYHDMDNSEQRFIETLISKGNPVTIVNSRDVNMLKLTNHLGFVYQLNEDEFFVNNFFLRYINSEVLDNAYGEFESLDTINHMNLNEEVLRVRQHTRLNDVTLEHALLLKTNDELKTICRQYGIKGFSNKNKQNLVELIMTAFFNNNHIIEQVFSNATLFEFDILSSILESDDNYRLNNELTKFEKLQLINFDNFLTIHFYYYYDFEYDCLILPNDVRKHIENFVNQVGNGYFEKAVNQFVDEQTIENSLAEFKNALELSFMEDEVDLDMLLEDDDFEDFGTTDSLRSDAITQLISEIKKGLIDKKDILPLRIILGSVNLYGILSTNHLLYLLQRFYDATFSKEELQYSLDTLAGTELYYVEDDFVFHPVLFDVVESEASGIDISDDGYYVPASVEELIYYDRHHYLKSDQAIKEFTSYLRKQINMKNDIEKEKYVNEIIMLLRTIPTSKLIQPIMQLFIDNAILNNVQNDALLIEKATHARNHLRLWSLQGHRDIPN
>CP029649.1|AWQ67657.1|1391360_1391987_+|hypothetical-protein
MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>CP029649.1|AWQ65208.1|1392055_1392181_-|hypothetical-protein
MRQLMGDFGIDREFKAIKKASNSNMLLDAQMMTLAKLISHF
>CP029649.1|AWQ66359.1|1392242_1392626_+|putative-membrane-protein
MKVRITFIILSILSTIVCLFLAAMHPTGPSTVTFEQPYLFTLNIIIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFTSTIITLAIGGKSVDKNDSH
>CP029649.1|AWQ66631.1|1392691_1393273_-|histidine-phosphatase-super-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQQDDIVIVAHQVVIRCLMVYFNNVSREEAVDLKVENCKPYIIE
>CP029649.1|AWQ66614.1|1393702_1393954_-|transglycosylase-associated-family-protein
MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWLGGTLLGQWGPEIGRIYILPALIGSIILIAIVTLILRAMRK

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Crispr_ID: CP029649_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029649_6

1524210-1524300

Orphan

Consensus_repeat	Method
TTCTACAGACAATGCAAGTTGGGGTGTGGGCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029649_6

>merge|CP029649|6|1524210-1524300|CRISPRCasFinder
TTCTACAGACAATGCAAGTTGGGGTGTGGGCCCCAACAAAGAGAATTTCGAAAAGAAATTCTACAGGCAATGCAAGTTGGGGTGTGGGCCC

>CP029649|6|6|1524210-1524300|CRISPRCasFinder
TTCTACAGACAATGCAAGTTGGGGTGTGGGCCC	CAACAAAGAGAATTTCGAAAAGAAA
TTCTACAGGCAATGCAAGTTGGGGTGTGGGCCC

Protein	Signature genes	Signature genes Name	Protein_function
CP029649.1\|AWQ66045.1\|1522618_1523788_-\|Poly(glycerophosphate)-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
CP029649.1\|AWQ66078.1\|1520608_1521634_-\|zinc-binding-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|176199
CP029649.1\|AWQ65960.1\|1516326_1517001_-\|iron-sulfur-cluster-repair-di-iron-protein	unknown	unknown	gnl\|CDD\|183940
CP029649.1\|AWQ66760.1\|1530031_1531087_-\|D-arabitol-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|176219
CP029649.1\|AWQ66421.1\|1528816_1529860_-\|alcohol-dehydrogenase-GroES-like-domain-protein	unknown	unknown	gnl\|CDD\|176198
CP029649.1\|AWQ66769.1\|1532891_1533359_-\|phosphoenolpyruvate-dependent-sugar-phosphotransferase-system,-EIIA-2-family-protein	unknown	unknown	gnl\|CDD\|238129
CP029649.1\|AWQ67314.1\|1514328_1516083_-\|histidine-kinase-,-DNA-gyrase-B-,-and-HSP90-like-ATPase-family-protein	unknown	unknown	gnl\|CDD\|225814
CP029649.1\|AWQ67440.1\|1513029_1513467_-\|lrgA-family-protein	unknown	unknown	gnl\|CDD\|235222
CP029649.1\|AWQ65383.1\|1513585_1514326_-\|sensory-transduction-protein-LytR	unknown	unknown	gnl\|CDD\|184495
CP029649.1\|AWQ66761.1\|1533343_1535440_-\|PRD-domain-protein	unknown	unknown	gnl\|CDD\|226234
CP029649.1\|AWQ66216.1\|1531104_1532364_-\|PTS-system,-galactitol-specific-IIC-component-family-protein	unknown	unknown	gnl\|CDD\|226298
CP029649.1\|AWQ67648.1\|1517144_1518866_-\|glycosyl-transferase-2-family-protein	unknown	unknown	gnl\|CDD\|376098
CP029649.1\|AWQ67014.1\|1526554_1527580_-\|alcohol-dehydrogenase-GroES-like-domain-protein	unknown	unknown	gnl\|CDD\|176199
CP029649.1\|AWQ66298.1\|1512335_1513037_-\|lrgB-like-family-protein	unknown	unknown	gnl\|CDD\|179810
CP029649.1\|AWQ67338.1\|1529883_1530030_-\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ66681.1\|1518898_1520587_-\|Poly(glycerophosphate)-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
CP029649.1\|AWQ66755.1\|1524838_1526533_-\|Poly(glycerophosphate)-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
CP029649.1\|AWQ66802.1\|1527572_1528289_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	unknown	unknown	gnl\|CDD\|184017
CP029649.1\|AWQ66209.1\|1521626_1522343_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184017
CP029649.1\|AWQ65783.1\|1532590_1532869_-\|PTS-system,-Lactose/Cellobiose-specific-IIB-subunit	unknown	unknown	gnl\|CDD\|99908

Protein	Function_ID	Function_description	E-value
CP029649.1\|AWQ66045.1\|1522618_1523788_-\|Poly(glycerophosphate)-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	1.25735e-161
CP029649.1\|AWQ66078.1\|1520608_1521634_-\|zinc-binding-dehydrogenase-family-protein	gnl\|CDD\|176199	cd08237, ribitol-5-phosphate_DH, ribitol-5-phosphate dehydrogenase. NAD-linked ribitol-5-phosphate dehydrogenase, a member of the MDR/zinc-dependent alcohol dehydrogenase-like family, oxidizes the phosphate ester of ribitol-5-phosphate to xylulose-5-phosphate of the pentose phosphate pathway. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability.	0
CP029649.1\|AWQ65960.1\|1516326_1517001_-\|iron-sulfur-cluster-repair-di-iron-protein	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	7.18502e-154
CP029649.1\|AWQ66760.1\|1530031_1531087_-\|D-arabitol-phosphate-dehydrogenase	gnl\|CDD\|176219	cd08258, Zn_ADH4, Alcohol dehydrogenases of the MDR family. This group shares the zinc coordination sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of an beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.06411e-146
CP029649.1\|AWQ66421.1\|1528816_1529860_-\|alcohol-dehydrogenase-GroES-like-domain-protein	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	9.45294e-176
CP029649.1\|AWQ66769.1\|1532891_1533359_-\|phosphoenolpyruvate-dependent-sugar-phosphotransferase-system,-EIIA-2-family-protein	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	1.27465e-37
CP029649.1\|AWQ67314.1\|1514328_1516083_-\|histidine-kinase-,-DNA-gyrase-B-,-and-HSP90-like-ATPase-family-protein	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
CP029649.1\|AWQ67440.1\|1513029_1513467_-\|lrgA-family-protein	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	2.74631e-64
CP029649.1\|AWQ65383.1\|1513585_1514326_-\|sensory-transduction-protein-LytR	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	4.37999e-152
CP029649.1\|AWQ66216.1\|1531104_1532364_-\|PTS-system,-galactitol-specific-IIC-component-family-protein	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	0
CP029649.1\|AWQ67648.1\|1517144_1518866_-\|glycosyl-transferase-2-family-protein	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	6.64158e-35
CP029649.1\|AWQ67014.1\|1526554_1527580_-\|alcohol-dehydrogenase-GroES-like-domain-protein	gnl\|CDD\|176199	cd08237, ribitol-5-phosphate_DH, ribitol-5-phosphate dehydrogenase. NAD-linked ribitol-5-phosphate dehydrogenase, a member of the MDR/zinc-dependent alcohol dehydrogenase-like family, oxidizes the phosphate ester of ribitol-5-phosphate to xylulose-5-phosphate of the pentose phosphate pathway. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability.	8.17637e-179
CP029649.1\|AWQ66298.1\|1512335_1513037_-\|lrgB-like-family-protein	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
CP029649.1\|AWQ66761.1\|1533343_1535440_-\|PRD-domain-protein	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	9.95484e-84
CP029649.1\|AWQ66681.1\|1518898_1520587_-\|Poly(glycerophosphate)-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	4.42901e-119
CP029649.1\|AWQ66755.1\|1524838_1526533_-\|Poly(glycerophosphate)-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	1.00668e-114
CP029649.1\|AWQ66802.1\|1527572_1528289_-\|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase	gnl\|CDD\|184017	PRK13385, PRK13385, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Provisional.	3.70751e-127
CP029649.1\|AWQ66209.1\|1521626_1522343_-\|hypothetical-protein	gnl\|CDD\|184017	PRK13385, PRK13385, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Provisional.	2.28851e-105
CP029649.1\|AWQ65783.1\|1532590_1532869_-\|PTS-system,-Lactose/Cellobiose-specific-IIB-subunit	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.43648e-34

>CP029649.1|AWQ66045.1|1522618_1523788_-|Poly(glycerophosphate)-glycerophosphotransferase-family-protein
MIKTTIKKLIEHSIYTTFKLLSKLPNKNLIYFESFHGKQYSDNPKALYEYLTEHSDAQLIWGVKKGYEHIFQQHNVPYVTKFSMKWFLAMPRAKAWMINTRTPDWLYKSPRTTYLQTWHGTPLKKIGLDISNVKMLGTNTQNYQDGFKKESQRWDYLVSPNPYSTSIFQHAFHVSRDKILETGYPRNDKLSHKRNDTEYINGIKTRLNIPLDKKVIMYAPTWRDDEAIREGSYQFNVNFDIEALRQALDDDYVILLRMHYLVVTRIDEHDDFVKDVSDYEDISDLYLISDALVTDYSSVMFDFGVLKRPQIFYAYDLDKYGDELRGFYMDYKKELPGPIVENQTALIDALKQIDETTNEYIEARTVFYQKFCSLEDGHASQRICQTIFK
>CP029649.1|AWQ66209.1|1521626_1522343_-|hypothetical-protein
MKYAGILAGGIGSRMGNVPLPKQFLDLDNKPILIHTLEKFILINDFEKIIIATPQQWMTHTKDTLRKFKISDERIEVIQGGSDRNDTIMNIVKHIESTNGINDDDVIVTHDAVRPFLTHRIIKENIQAALEYGAVDTVIDAIDTIVTSKDNQTIDAIPVRNEMYQGQTPQSFNINLLKESYAQLSDEQKSILSDACKIIVETNKPVRLVKGELYNIKVTTPYDLKVANAIIRGGIADD
>CP029649.1|AWQ66078.1|1520608_1521634_-|zinc-binding-dehydrogenase-family-protein
MINQVYQLVAPRQFEVTYNNVDIYSDYVIVRPLYMSICAADQRYYTGSRDENVLSQKLPMSLIHEGVGEVVFDSKGVFNKGTKVVMVPNTPTETDDVIAENYLKSSYFRSSGHDGFMQDFVLLNHDRAVPLPDDIDLSIISYTELVTVSLHAIRRFEKKSISNKNTFGIWGDGNLGYITAILLRKLYPESKIYVFGKTDYKLSHFSFVDDVFFINKIPEGLTFDHAFECVGGRGSQSAINQMIDYISPEGSIALLGVSEFPVEVNTRLVLEKGLTLIGSSRSGSKDFQDVVDLYIQYPDIVDKLALLKGQEFEIATINDLTEAFEADLSTSWGKTVLKWIM
>CP029649.1|AWQ66681.1|1518898_1520587_-|Poly(glycerophosphate)-glycerophosphotransferase-family-protein
MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRTMKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQNLKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDVVVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSDSRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIFVDDFHPLIYTVRFRRSQEVIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYFVDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS
>CP029649.1|AWQ67648.1|1517144_1518866_-|glycosyl-transferase-2-family-protein
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTTLLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISLKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>CP029649.1|AWQ65960.1|1516326_1517001_-|iron-sulfur-cluster-repair-di-iron-protein
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>CP029649.1|AWQ67314.1|1514328_1516083_-|histidine-kinase-,-DNA-gyrase-B-,-and-HSP90-like-ATPase-family-protein
MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>CP029649.1|AWQ65383.1|1513585_1514326_-|sensory-transduction-protein-LytR
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>CP029649.1|AWQ67440.1|1513029_1513467_-|lrgA-family-protein
MKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>CP029649.1|AWQ66298.1|1512335_1513037_-|lrgB-like-family-protein
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>CP029649.1|AWQ66755.1|1524838_1526533_-|Poly(glycerophosphate)-glycerophosphotransferase-family-protein
MTKTKQAIHIDNIYWERVQLYIEGHSEGVDLTSGQFVLRNLTETKTLEANEMKIDGNTFICRFNVAILDDGYYLPMDKYLFVYHDQLEYIGQLNPNIIDQAYAALNEEQIEEYNELTTQNGKVNYLLAYDAKVFRKGGVSQHTVYTITPEIASDVNEFVFDIEITLPQEKSGVIATSAHWLHKQGHKASFESRSFLFKAIFNITKLLHIKRSKTILFTSDSRPNLSGNFKYVYDELLRQKVDFDYDIKTVFKANITDRRKWRDKFRLPYLLGKADYIFVDDFHPLIYTVRFRPSQEIIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIREENVVPTGVPRTDVLFDETYATQIKQEMEDELPIIKGKKVILFAPTFRGNGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNISREHRQYFIDVSDYREVNDILFVTDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEVEKVVPFLDKHFKYQDGRSSERLVKDLFRR
>CP029649.1|AWQ67014.1|1526554_1527580_-|alcohol-dehydrogenase-GroES-like-domain-protein
MINQVYQLVAPRQFDVTYNNVDIYGNHVIVRPLYLSICAADQRYYTGRRDENVLRKKLPMSLVHEAVGEVVFDSKGVFEKGTKVVMVPNTPTEQHHIIAENYLASSYFRSSGYDGFMQDYVVMAHDRIVPLPNDIDLSTISYTELVSVSYHAIQRFERKSIPLKTSFGIWGDGNLGYITAILLRKLYPEAKTYVFGKTDYKLSHFSFVDDIFTVNQIPDDLKIDHAFECVGGKGSQVALQQIVEHISPEGSIALLGVSELPVEVNTRLVLEKGLTLIGSSRSGSKDFEQVVDLYRKYPDIVEKLALLKGHEINVCTMQDIVQAFEKDLSTSWGKTVLKWTI
>CP029649.1|AWQ66802.1|1527572_1528289_-|2-C-methyl-D-erythritol-4-phosphate-cytidylyltransferase
MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVSEFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAGGTDRNETIMNIIDHIRNVNGINNDDVIVTHDAVRPFLTQRIIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVRNEMYQGQTPQSFNIKLLQDSYRALSSEQKEILSDACKIIVESGHAVKLVRGELYNIKVTTPYDLKVANAIIQGDIADD
>CP029649.1|AWQ66421.1|1528816_1529860_-|alcohol-dehydrogenase-GroES-like-domain-protein
MKALKLYGVEDLRYEDNEKPVIESANDVIIKVRATGICGSDTSRYKKMGPYIKGMPFGHEFSGVVDAIGSDVTHVNVGDKVTGCPAIACYQCGYCLKGEYARCEKLFVIGSYEPGSFAEYVKLPAQNVLKVPDNVDYIEAAMVEPSAVVAHGFYKSNIQPGMTVAVMGCGSIGLLAIQWARIFGAAHIIAIDIDAHKLDIATSLGAHQTINSKEENLEKFIENHYANQIDLAIESSGAKVTIGQILTLPKKGGEVVLLGIPYDDIEIDRVHFEKILRNELTVCGSWNCLSSNFPGKEWTATLHYMKTKDINVKPIISHFLPLEKGPETFDKLVNKKERFDKVMFTIY
>CP029649.1|AWQ67338.1|1529883_1530030_-|hypothetical-protein
MVESMLTFMLGPLRQITDFYMEHLLVSNSIVIAGYFATGIFKKKKVVN
>CP029649.1|AWQ66760.1|1530031_1531087_-|D-arabitol-phosphate-dehydrogenase
MKALVKTREGHGNLELLDKEVATPLDDKVKIKVHYAGICGTDIHTYEGHYKVNFPVTLGHEFSGEIVEVGADVKDFKVGDRVTSETTFYVCNECEYCKSKDYNLCNHRKGIGTQVDGAFTNYVIAREESLHHIPDEVSYQSAAMTEPLACAHHGVSKIQVNSGDVAVVMGPGPIGLLVAQVLKSKGATVVVTGLDNDKVRLDKAEALHMDYVVNLQQTDLKTYINGITDGYGADVVVECSGAVPAARQGLDILRKKGFYSQIGIFKDAEIPFDMEKVIQKEITVVGSRSQKPADWEPSLQLMADGLVNAEALVTKIYDISKWDEAYQHLKSGEGIKALLKPLDLDENEGEN
>CP029649.1|AWQ66216.1|1531104_1532364_-|PTS-system,-galactitol-specific-IIC-component-family-protein
MSYFTDFVRGFLDLGATVILPVVIFLLGLFFRQKIGAAFRSGLTIGVAFVGIFLVIDLLVKNLGPAAQAMVKNLGVSLNVIDVGWPATSSIAWASSVAAFIIPLGIIVNVVLLVTKVTKTMNVDIWNFWHYTFTAAMVYAVSGSIWQALLAAVIFQVICLKVADWTAPMMSEFFDLPGVSIATGSTISYAPGIYLVKLLQKVPGLNKLDADPETIQKRFGAFGESIFVGLILGLGIGVLAGYKPGDIINLGMSMAAVMVLMPRMVKILMEGLMPVSESARTWLNKRFGEREIYIGLDAAVALGHPAVISTALILVPITVLLAVILPGNQVLPFDDLATIPFVVAFIVGAARGNIIHSVIVGTIMIAISLYIATDVAPIFTDMAKGTNVQMPKGSSEISSIDQGGNIVNYLIFKLFSLFN
>CP029649.1|AWQ65783.1|1532590_1532869_-|PTS-system,-Lactose/Cellobiose-specific-IIB-subunit
MKQVLVACGAGIATSTVVNNAIEEMAKEHNIKVDIKQIKITEVGPYEDTADLLVTTAMTKKEYKFPVINARNFLTGIGIEETKQQILTELQK
>CP029649.1|AWQ66769.1|1532891_1533359_-|phosphoenolpyruvate-dependent-sugar-phosphotransferase-system,-EIIA-2-family-protein
MGQQLVHKENIMLNLSATDKESVLSQMSDVLFQNGFVKSTFKDAVIDREKEFATGLPTHLCSVAIPHTDVEHINHRTIGVAVLEKEVPFIEMGTLDQQTEVKIVFMLAMDKVDDQLKLLQQLMQIFQSEEKLEQILRTKDETILATLINDYLEYN
>CP029649.1|AWQ66761.1|1533343_1535440_-|PRD-domain-protein
MNGDNQQILREIVLNPTIHGKELESIFGLSRRQLGYRIQKINLWLEQEGYPKLERTSQGNFIVSSEIMTLFKRDVSEQQMLNGNNVIFSIETRRYYLMLMLFSKENAMSLNHFSIDLQVSKNTVIHDINHVKEQLEDHGLSLKYSRKHGYEIVGDEFEVRRFFIKLIDQRLNHDITKSEVLKALNLTFEDIAYQKDKIKQVEQFLKSRFIDKSLSSLPYVLCVIRRRIQSGHVMNPLNINYQYLRDTKEYQATEIMTQHEPDLPEAEKLYLTLHLLSTSVQWTDLQESDSISNLTMAIAQMIHHFEQITFINIEDKEKLSQQLLLHLTPAFYRIKYNLTDRDELINPLQGNYQSLFHMVKQSCQSLTEYFGKSLPDNEIAYLTMLFGGSLRRQDENFDGKIKAIIVCTQGTSVSQMMLYELRNLFPEIIFLDAISLRTFENYTLDYDIVFSPMFVLTHKKLFITKVALSENEQRKLRKEVMKYINKESADIDKEINKLMALIERTTTVNDITELRDGLEDFIANYNSISTINGSIVTQNKTLDLADLIPARHVKRIHHVENIDEAIAKASDVLVANHFIDIKYIHEMQQVFDDSYMVIMQNIAIPHAYSEKHVHKTAMSMLILQEPIYMSDGTAIHIIVPIAAVDKVTHLRALLQLRDVAQDNDAIKRIIQSRKNSDVNEILKNYSNKEARENGWDSN

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Crispr_ID: CP029649_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029649_7

1725199-1725450

TypeIII

Consensus_repeat	Method
AGTTCTCGTCCCCTCTTCTACGGGNGTAGTTATCGAAT	CRT
CTCGTCCCCTCTTCTACGGGGTAGTTATCGAAT	CRISPRCasFinder
GAGTTCTCGTCCCCTCTTCTACGGGGTAGTTATCGAAT	PILER-CR

3 spacers

cas6,csm6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,cas2,cas1

The CRISPR arrays of CP029649_7

>merge|CP029649|7|1725199-1725450|CRT,CRISPRCasFinder,PILER-CR
GATCCTCGTCCCCTCTTCTACGGGGTAGTTATCGAATGCATAAAGTTTTGATATACACGATCGAATATGAGTTCTCGTCCCCTCTTCTACGGGGTAGTTATCGAATAGTGGTCCAGAATTAATACATGGTAAAGGAGTATATCAGTTCTCGTCCCCTCTTCTACGGGGGTAGTTATCGAATGAAGACCAATTAGAATCATATCGCGTCTTAGAAGAGTTCTCGTCCCCTCTTCTACGGGGTAGTTATCGAAT

>CP029649|7|1|1725199-1725450|CRT
GATCCTCGTCCCCTCTTCTACGGGGTAGTTATCGAAT	GCATAAAGTTTTGATATACACGATCGAATATG
AGTTCTCGTCCCCTCTTCTACGGGGTAGTTATCGAAT	AGTGGTCCAGAATTAATACATGGTAAAGGAGTATATC
AGTTCTCGTCCCCTCTTCTACGGGGGTAGTTATCGAA	TGAAGACCAATTAGAATCATATCGCGTCTTAGAAG
AGTTCTCGTCCCCTCTTCTACGGGGTAGTTATCGAAT

>CP029649|7|7|1725203-1725450|CRISPRCasFinder
CTCGTCCCCTCTTCTACGGGGTAGTTATCGAAT	GCATAAAGTTTTGATATACACGATCGAATATGAGTT
CTCGTCCCCTCTTCTACGGGGTAGTTATCGAAT	AGTGGTCCAGAATTAATACATGGTAAAGGAGTATATCAGTT
CTCGTCCCCTCTTCTACGGGGGTAGTTATCGAA	TGAAGACCAATTAGAATCATATCGCGTCTTAGAAGAGTT
CTCGTCCCCTCTTCTACGGGGTAGTTATCGAAT

>CP029649|7|1|1725267-1725450|PILER-CR
GAGTTCTCGTCCCCTCTTCTACGGGGTAGTTATCGAATA	GTGGTCCAGAATTAATACATGGTAAAGGAGTATATC
AGTTCTCGTCCCCTCTTCTACGGGGGTAGTTATCGAATG	AAGACCAATTAGAATCATATCGCGTCTTAGAAG
AGTTCTCGTCCCCTCTTCTACGGGGTAGTTATCGAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP029649.1\|AWQ65836.1\|1730173_1730599_-\|hypothetical-protein	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|273844
CP029649.1\|AWQ67031.1\|1724316_1724475_-\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ65713.1\|1729527_1730172_-\|RAMP-superfamily-protein	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
CP029649.1\|AWQ67261.1\|1723121_1724057_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372918
CP029649.1\|AWQ66108.1\|1725584_1726319_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
CP029649.1\|AWQ66052.1\|1717348_1718263_+\|alpha/beta-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223999
CP029649.1\|AWQ66013.1\|1720222_1721209_+\|putative-tRNA-dihydrouridine-synthase	unknown	unknown	gnl\|CDD\|223120
CP029649.1\|AWQ67081.1\|1721276_1721399_-\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ65174.1\|1730601_1732875_-\|HD-domain-protein	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
CP029649.1\|AWQ67010.1\|1732888_1733194_-\|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09638_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|273699
CP029649.1\|AWQ65748.1\|1716615_1717170_-\|bacterial-regulatory,-tetR-family-protein	unknown	unknown	gnl\|CDD\|274100
CP029649.1\|AWQ66792.1\|1715648_1716380_-\|methyltransferase-domain-protein	unknown	unknown	gnl\|CDD\|181382
CP029649.1\|AWQ67128.1\|1727583_1728606_-\|RAMP-superfamily-protein	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
CP029649.1\|AWQ65441.1\|1735527_1735788_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378743
CP029649.1\|AWQ66896.1\|1728608_1729442_-\|putative-cRISPR-associated-RAMP-protein	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|273866
CP029649.1\|AWQ67488.1\|1719365_1719662_-\|tfoX-N-terminal-domain-protein	unknown	unknown	gnl\|CDD\|225612
CP029649.1\|AWQ66910.1\|1721455_1723129_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274009
CP029649.1\|AWQ65683.1\|1718554_1719157_-\|putative-membrane-protein	unknown	unknown	unknown
CP029649.1\|AWQ66292.1\|1726315_1727584_-\|CRISPR-associated-family-protein	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|131720
CP029649.1\|AWQ65958.1\|1733193_1734099_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851

Protein	Function_ID	Function_description	E-value
CP029649.1\|AWQ65836.1\|1730173_1730599_-\|hypothetical-protein	gnl\|CDD\|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	7.59929e-21
CP029649.1\|AWQ65713.1\|1729527_1730172_-\|RAMP-superfamily-protein	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	7.36094e-106
CP029649.1\|AWQ67261.1\|1723121_1724057_-\|hypothetical-protein	gnl\|CDD\|372918	pfam14130, DUF4297, Domain of unknown function (DUF4297). This presumed domain is functionally uncharacterized. This domain family is found in bacteria and archaea, and is typically between 207 and 221 amino acids in length.	0.00217205
CP029649.1\|AWQ66108.1\|1725584_1726319_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	7.10684e-15
CP029649.1\|AWQ66052.1\|1717348_1718263_+\|alpha/beta-hydrolase-family-protein	gnl\|CDD\|223999	COG1073, COG1073, Hydrolases of the alpha/beta superfamily [General function prediction only].	2.42079e-31
CP029649.1\|AWQ66013.1\|1720222_1721209_+\|putative-tRNA-dihydrouridine-synthase	gnl\|CDD\|223120	COG0042, COG0042, tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis].	8.4044e-98
CP029649.1\|AWQ65174.1\|1730601_1732875_-\|HD-domain-protein	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
CP029649.1\|AWQ67010.1\|1732888_1733194_-\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|273699	TIGR01573, cas2, CRISPR-associated endonuclease Cas2. This model describes most members of the family of Cas2, one of the first four protein families found to mark prokaryotic genomes that contain multiple CRISPR elements. CRISPR systems protect against invasive nucleic acid sequences, including phage. Cas2 proteins have been characterized as either endoribonuclease (for ssRNA) or endodeoxyribonuclease (for dsDNA), depending on the system to which the Cas2 belongs. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats. The cas genes usually are found near the repeats. A distinct branch of the Cas2 family shows a very low level of sequence identity and is modeled by TIGR01873 instead of by this model (TIGR01573).	4.06918e-22
CP029649.1\|AWQ65748.1\|1716615_1717170_-\|bacterial-regulatory,-tetR-family-protein	gnl\|CDD\|274100	TIGR02366, conserved_hypothetical_protein, probable dihydroxyacetone kinase regulator. The seed alignment for this family was built from a set of closely related uncharacterized proteins associated with operons for the type of bacterial dihydroxyacetone kinase that transfers PEP-derived phosphate from a phosphoprotein, as in phosphotransferase system transport, rather than from ATP. Members have a TetR transcriptional regulator domain (pfam00440) at the N-terminus and sequence homology throughout.	1.01012e-12
CP029649.1\|AWQ66792.1\|1715648_1716380_-\|methyltransferase-domain-protein	gnl\|CDD\|181382	PRK08317, PRK08317, hypothetical protein; Provisional.	1.69527e-28
CP029649.1\|AWQ67128.1\|1727583_1728606_-\|RAMP-superfamily-protein	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.06095e-17
CP029649.1\|AWQ65441.1\|1735527_1735788_+\|hypothetical-protein	gnl\|CDD\|378743	pfam11867, DUF3387, Domain of unknown function (DUF3387). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is typically between 255 to 340 amino acids in length. This domain is found associated with pfam04851, pfam04313.	3.1971e-31
CP029649.1\|AWQ66896.1\|1728608_1729442_-\|putative-cRISPR-associated-RAMP-protein	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	4.83771e-38
CP029649.1\|AWQ67488.1\|1719365_1719662_-\|tfoX-N-terminal-domain-protein	gnl\|CDD\|225612	COG3070, TfoX, Regulator of competence-specific genes [Transcription].	7.78757e-21
CP029649.1\|AWQ66910.1\|1721455_1723129_-\|hypothetical-protein	gnl\|CDD\|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	5.2246e-06
CP029649.1\|AWQ66292.1\|1726315_1727584_-\|CRISPR-associated-family-protein	gnl\|CDD\|131720	TIGR02672, hypothetical_protein_SERP2456, CRISPR type III-A/MTUBE-associated protein Csm6. Members of this family as found in CRISPR-associated (cas) gene regions in Streptococcus thermophilus CNRZ1066, Staphylococcus epidermidis RP62A, and Mycobacterium tuberculosis (strains CDC1551 and H37Rv), as part of Mtube-type CRISPR/Cas systems. CRISPR is a widespread form of direct repeat found in archaea and bacteria, with distinctive subtypes each of which has a characteristic sporadic distribution.	1.16357e-132
CP029649.1\|AWQ65958.1\|1733193_1734099_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.00185e-113

>CP029649.1|AWQ67031.1|1724316_1724475_-|hypothetical-protein
MKFKSKQLVIANQTKVINYRIQVLLKPQANIETQTQVKNNTLPETDEQSNAD
>CP029649.1|AWQ67261.1|1723121_1724057_-|hypothetical-protein
MVRENGGANAQRGFNYQNCVISLVAIRNYKKPNFKIYVEADEDFEVNYGDDYHACIQVKGEKNLTFNKLLKGENGKLSIFEKNLSSGKSDSVYKIVVFSFSRKDMESMQEQTDEEELFSNSWLLSNDQKNKVNNDRVENFSLVKTAFDNDMKNARIYLKGELVQQNIVVEGRAEVILNELFQQILQKSEKKVQTEQDKELKKITSKELDLILQKITAKARFEKELKNLRFNSLKEEKIKKEEKKIILEYMAVKKAVIRFLKSDEEKLENNSISTLISETFNLSEMNCLSENTKYAIAISAYCDILEEIAYE
>CP029649.1|AWQ66910.1|1721455_1723129_-|hypothetical-protein
MNKLTIISLSILDNKEKKANKFEFSEKSNLIISERNGEGKSSLIKSIQYCLGSNLKAFPKGWDYKNYVFQLEIVIDKNKILIQRYNNIITVLDDGKIKKFGYLKDYSDWFQDKMEMNLKLVSKNKNTSSLASLEAILSPLYIDQDKSWDGILYKNSFEGLAQYKSQSFPKEVFEYYLGISNNIMNDKINKLNKYREKSKEKKVKIEQVDSVYKNYSSQKNISKTIPKEFEEFKKQVDFYIKETDRFSQMITQKTDKLSKEKMKLDILQQDREELRKLLTKTKKRLSEVSYECTYCHSVLTRGQSLTRMELDDNKIEILLRKDSINQEIIKIENNIQKKLIEIQNLENQFELYHERLSELKQLSNIDNYVNQKVLQELETLKIEEVIELKEIDQEIKSLRNEISKLKKSLKTDLENINQKFKKLKNKISLQMETTGLSEKKVLNFNKLNGSGTFLNKDLLTLYLVYMNLLDSMEDFGLPFAIDSFVKNETDSIALEKMFGAIDKYFLTLNNQTFFSIIKENLKFIENPVNEIKIERPLLKEKFFSDIEKELIQNLNIL
>CP029649.1|AWQ67081.1|1721276_1721399_-|hypothetical-protein
MKMLFFLYFFFLKLYNHFLTQPLIGDQMIVTQEQLKDIMK
>CP029649.1|AWQ66013.1|1720222_1721209_+|putative-tRNA-dihydrouridine-synthase
MKENFWSELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEFTNTESFCHPEGIHSVRGRLTFSEDEHPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLNMGCPVANVAKKGKGSGLILRPDVAAEIIQATKAGGLPVSVKTRLGYYEIDEWKDWLKHVFEQDIANLSIHLRTRKEMSKVDAHWELIEAIKNLRDEIAPNTLLTINGDIPDRKTGLELAEKYGIDGVMIGRGIFHNPFAFEKEPREHTSKELLDLLRLHLSLFNKYEKDEIRQFKSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARALLDEFEAQMDEDVKIEL
>CP029649.1|AWQ67488.1|1719365_1719662_-|tfoX-N-terminal-domain-protein
MATEKDINDLFLNHVNSNAVKTRKMMGEYIIYYDGVVIGGLYDNRLLVKATKSAQQKLQDNTLVSPYPGAKEMILIPDFTEATNLTDLFKTIKNDLKN
>CP029649.1|AWQ65683.1|1718554_1719157_-|putative-membrane-protein
MLISLVTPVFALLVIGGIIWVIIEGIVHISKKNKAIDNFLNQVNKVSETYKFATTFLFLILATAGISQFYLYYIVSAFLFWLVILTFGIAGIIFLMPYGLCFLPFYKQKKKKQTFKKYMVYTTIGLSICLGLSLVLVHTTKIYMDEGGVRYYYGSFVMKQAGGYAYLALAVLSTLLIVAKKATNKNKEIETVDNTNIMER
>CP029649.1|AWQ66052.1|1717348_1718263_+|alpha/beta-hydrolase-family-protein
MKQSVNFKSKTNLLAANLYTPEQFDESKKYPAITVCHPGGGVKEQTAGMYAEKLAEFGYVTVVYDASHQGESEGSPRYLEDPFARTEDVRASVDYLTTLDFVDNDRIGALGVCAGGGYTVSAARTERRIKALATVSMVDIGALFRKGPGDVVSIDDQLAFMTQVADQRTAEANGADYGITGYVPEEIDDSMPENSTMVQGHDYYLTARGQHKNAPNKLLLRSFSEVLTFAPFTYIDELLTQPFLAIAGTEADTIEYSVDAVEKAAGDNNELYKIEGASHVDLYDIPEYVNQVLPKLESFYKETL
>CP029649.1|AWQ65748.1|1716615_1717170_-|bacterial-regulatory,-tetR-family-protein
MNVGDLRVVKTRASIKKAFITLLFEKDFDTISIKEITEFAQIGRKTFYLHYIDKYDLLDQIVSEKLTELEQISEAKKSLGIQEGTQLWFEFFENNRTFFMKIFNINNASNYKKKLLHFIEEEFKKKVPTRVATEKGLDYDLYINFISNGIIGLLDIYLNSSENTEEQEKITLQVSRLLSLYDLI
>CP029649.1|AWQ66792.1|1715648_1716380_-|methyltransferase-domain-protein
MQNRNDFIEKLLDRAQIKDGMRVLDIGCATGEVTQLIAKRVGANGEVVGVDVNESLLKIANENNQYNNVSYQYSDIYQLPETMGHFDAIVGRRVLMYLPDAEKCLQILKSILKPEGILCFQESDAINTGVGADALPLHQSAIQWIWETVKQEGGNIHIGQNLYNLFNNNGMHVVDYFAEAVIQTSMDNDLAWLVDVMLPRMKAHGVINDDFSLDEFKSNLEQEAINNQCAFIRDMAFGIIGKA
>CP029649.1|AWQ66108.1|1725584_1726319_-|CRISPR-associated-endoribonuclease-Cas6
MINKITVELDLPDSIRFQYLGSILHGVLMDYLPNDIADQLHHEFAYSPLKQRIYHKNKKVIWEIVCMSDRLFNEIAELFTSKNRLFLKYYQVYIEIYSFNIEKVNVQNIMNQLLETEELNRYVRINIQTPMSFKYQSNYMIFPEVKRFFRSIMIQFDAFFEEYKMYDKETLDFLEKNINIVDYKLKSTRFNLEKVKIPSFTGEIVFKIKGPLPFLQLTHFLLKFGEFSGSGMKTSLGMGKYSII
>CP029649.1|AWQ66292.1|1726315_1727584_-|CRISPR-associated-family-protein
MKVLFSPIGNSDPWSNDRDGAMLHIVRHYKPDVVVLFFTESIWNGNRNIPGRKNFDWENIVSKVSSRTKVDIKVDSIKYENDFDSYKDIFHFYINEIRTKYSDAEILLNVTSGTPQMESTLCLEYISNPHNMKCIQVSTPAPIEGPKRSFAKLETVTEDLNKVNANEKMASNRSKSINIISFREVMVRSQIKSLVNNYDYEGALNLVSDQKSFRNGKLLRKRLLELTNQIKTHEVFPEINDKYRSVALKKSLFHYLLLNMRYNRLDVAETLIRVKSIAEFILKTYIVGHWPTLIIEKDDKPYLNAEDNLSFIYKYKLLLEKRRQNLDVSRILGLPAFIDILTVLEPNSKLLKEVNAVNDINGLRNSIAHNLETLDLDKNKNYKKIMLSVEAIKNMLHISFPEIEEKDYNYFERKNKEFRELL
>CP029649.1|AWQ67128.1|1727583_1728606_-|RAMP-superfamily-protein
MTIKNYEVVIKTLGPVHIGSGQVMKKQDYIYDFYNSKVYMINGNKLVKFLKRKNILDTYQNFLRYPPKNPRENGLKDYLDAQNVKQSEWKAFVSYSEKVNQGKKYGNIRPKPLNDLHLMVRDGQNKVYLPGSSIKGAIKTALVSKYNNEKNTDVYSKIKVSDSEPIDERHLAIYQKIDINKSEKPMPLYRECVDVDTEIKFKLTIEDEIYSINEIEQSIQDFYKNYYDKWLVGFKETKGGRRFALEGGMPDVLNQNILFLGAGAGFVSKTTHYQLKSREQAKRDSFDILTKKFRRTYGKMKEMPSNVPVALKGTTNQSLHVSYQQGMCKISFQELNNEVL
>CP029649.1|AWQ66896.1|1728608_1729442_-|putative-cRISPR-associated-RAMP-protein
MTITSDTLFSALFIEALQLGIETDWLLNDLIISDTFPYENEIYYLPKPLIKIESKEEGNHKAFKKLKYVPVHHYNQYLNGELSAEDATDLNDIFSIGHFSLQTKVSLSAQEIDSSADSEPYSVGTFTFEPEAGLYFIAKGSEETLDQLKDIMTSLQYSGLGGKRNAGYGQFEYEIINNQQLFKLLNQNGEHSILLSTAMAKEDEIKSALKEARYILNKRSGFIQSTNYSEMLVKKSDFYSFSSGSVFKNIFNGDVFNVGHNGKHPVYRYAKPLWLEV
>CP029649.1|AWQ65713.1|1729527_1730172_-|RAMP-superfamily-protein
MYSKIKISGTIEVVTGLHIGGGGESSMIGAIDSPVVRDLQTKLPIIPGSSIKGKMRSLLAKHFGLKMKQENHNQDDESVLRLFGSSEKGNIQRARLQISDAFFSEKTKEHFAQNDIAYTETKFENTINRLTAVANPRQIERVTRGSEFDFVFIYNVDEESQVENDFENIEKAIHLLENDYLGGGGTRGNGRIQFNDITIETVVGEYDSTNLKIK
>CP029649.1|AWQ65836.1|1730173_1730599_-|hypothetical-protein
MILAKTKSGKKIDLTFAHEVVKSNVKTVKDKRGKENQVLFNGLTTSKLRNLMEQVNRLYTIAFNSTEDQLNEEFIDELEYLKIKFYYEAGREKSVDEFLKKTLMFPIIDRVIQKESKKFFLDYCKYFEALVAYAKYYQKED
>CP029649.1|AWQ65174.1|1730601_1732875_-|HD-domain-protein
MDKKTTLMYGSLLHDIGKIIYRSNDHAFARGTHSKLGYNFLSQFSEFKDNEVLDSIAYHHYKELAKANLANDNTAYITYIADNIASGIDRRDVIEEGDEEYEKQAFNFDKYTPLYSVFNIVNSEKLKQISGKFKFSNESNIEYPKTENIQYSSGNYTTLMKDMSYDLEHKLSIKEDTFPSLLQWTESLWQYVPSSTNKNQLIDISLYDHSRITCAIASCIFDYLNENNIHNYKDELFTKYENTKEFYQKEAFLLLSMDMSGIQDFIYNISGSKALKSLRSRSFYLEIMLEVIVDQLLEKLELTRANLLYTGGGHAYLLVSNTDKGKEKINQFNTELKNWFMSEFTTDLSLSIAFEKCSGNDLMNTSGNYRNIWRNVSSKLSDIKAHKYSSEDILKLNHFHSYGDRECKECLRSDIDINDDGLCSICEGIINISNDLRDKSFFVLSETGKLKMPFDKFISVIDYEEAERLAQNNNHIRIYSKNKPYIGVGISTNLWMCDYDYASQNKDMREKGIGSYVEREEGIKRLGVVRADIDNLGATFISGIPEKYNSISRTATLSRQLSLFFKYELNHLLENYQITAIYSGGDDLFLIGAWDDIIEVSVYINEKFKDFTLGKLTMSAGVGMFSGKYPISKMAFETGLLEEAAKTDEKNQIALWVQEKVYNWDEFKKYILEEKLLVLQHGFSQTDEHGKAFIYKMLALLRNNETINIARLAYLLARSKMTEEFTSKIFNWAQNDKDKNQLITALEYYVYQIREVD
>CP029649.1|AWQ67010.1|1732888_1733194_-|CRISPR-associated-endoribonuclease-Cas2
MYLLVSFDLPRDTKFERRVASKYRTRLLELGFSMKQFSLYERYVSDVQKKDKILEILQQEIPDTGSITLYVLPDEVNNSQITILGKEVKVVVRKEPKLIFL
>CP029649.1|AWQ65958.1|1733193_1734099_-|CRISPR-associated-endonuclease-Cas1
MKDVIYVENHYFVTVKENSIKFRNVIDKSEKFYLFEEIEAIIFDHYKSYFSHKLVIKCIENDIAIIFCDKKHSPLTQLISSYGMTHRLQRIQSQFQLSGRTRDRIWKKIVVNKIINQSKCLENNLHNENVKLLVNLAKDVSSGDKSNKEAQAARIYFKDLYGKQFKRGRYNDIINSGLNYGYSILRSFIKKELALHGFEMSLGINHRSKENPFNLADDIIEVFRPFVDNIVYEIVFKKNINTFDVNEKKLLLNVLYEKCIIDKKVVRLLDSVKIVIQSLIRCYEENTPTYLLLPKMIEVGN
>CP029649.1|AWQ65441.1|1735527_1735788_+|hypothetical-protein
MAVELLNRLLKGQVKSLMKTNATVSKRFSEMLRNSINKYNSRSIETSKVIEELIQLAKDIKQEQQRGNELGLNSDEIAFLRCFSFT

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Crispr_ID: CP029649_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029649_8

1734173-1735063

TypeIII

Consensus_repeat	Method
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CRISPRCasFinder
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CRT
TTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	PILER-CR

12 spacers

cas1,cas2,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,csm6,cas6

The CRISPR arrays of CP029649_8

>merge|CP029649|8|1734173-1735063|CRISPRCasFinder,CRT,PILER-CR
CACTCTGTCCCCTGTTATTCGGGATAGTTATCGATCACCGACGTTTTATTACCTATTGAGCAACTATTACCGTTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCTACAAATGAATTAATCAGTGACATGAAAGATGAGTTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCCCTAAAATATTTTTATTAGGTAATGCCGTTAACTTATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCTAGAAAAAAGGAGGGTGTTATTCATGGAAGAAATATATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCTGATGTAAGAGAAATGATGAAAGATGACGAAGTTGTATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCCAAGAATTTAAAGATAACGAATTGAACGGGTTTATATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCACAGGATTGTATCTTTTAATAGAGAACAACACTATTAATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCGTAGACAGACACATAAAAAATTATGTAAATAGTATAATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCATCGGAATTAATGAACTTATAGAATTAGAAAATTATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCCAAGATCATAGATGATCTGAAAGGGTGGAAAAAAATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCAGATAATCTAGGTATCGGAATTAATGAACTTATAGAATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATCCAAAGTAGAACAATTAGCAGAAATGGCGAGAGAAGTATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC

>CP029649|8|8|1734173-1735063|CRISPRCasFinder
CACTCTGTCCCCTGTTATTCGGGATAGTTATCGATC	ACCGACGTTTTATTACCTATTGAGCAACTATTACC
GTTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	TACAAATGAATTAATCAGTGACATGAAAGATGA
GTTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CCTAAAATATTTTTATTAGGTAATGCCGTTAACTT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	TAGAAAAAAGGAGGGTGTTATTCATGGAAGAAATAT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	TGATGTAAGAGAAATGATGAAAGATGACGAAGTTGT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CAAGAATTTAAAGATAACGAATTGAACGGGTTTAT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	ACAGGATTGTATCTTTTAATAGAGAACAACACTATTA
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	GTAGACAGACACATAAAAAATTATGTAAATAGTATA
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	ATCGGAATTAATGAACTTATAGAATTAGAAAATT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CAAGATCATAGATGATCTGAAAGGGTGGAAAAAA
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	AGATAATCTAGGTATCGGAATTAATGAACTTATAGA
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CAAAGTAGAACAATTAGCAGAAATGGCGAGAGAAGT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC

>CP029649|8|2|1734173-1735063|CRT
CACTCTGTCCCCTGTTATTCGGGATAGTTATCGATC	ACCGACGTTTTATTACCTATTGAGCAACTATTACC
GTTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	TACAAATGAATTAATCAGTGACATGAAAGATGA
GTTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CCTAAAATATTTTTATTAGGTAATGCCGTTAACTT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	TAGAAAAAAGGAGGGTGTTATTCATGGAAGAAATAT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	TGATGTAAGAGAAATGATGAAAGATGACGAAGTTGT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CAAGAATTTAAAGATAACGAATTGAACGGGTTTAT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	ACAGGATTGTATCTTTTAATAGAGAACAACACTATTA
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	GTAGACAGACACATAAAAAATTATGTAAATAGTATA
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	ATCGGAATTAATGAACTTATAGAATTAGAAAATT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CAAGATCATAGATGATCTGAAAGGGTGGAAAAAA
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	AGATAATCTAGGTATCGGAATTAATGAACTTATAGA
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CAAAGTAGAACAATTAGCAGAAATGGCGAGAGAAGT
ATTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC

>CP029649|8|2|1734245-1734707|PILER-CR
TTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	TACAAATGAATTAATCAGTGACATGAAAGATGAG
TTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CCTAAAATATTTTTATTAGGTAATGCCGTTAACTTA
TTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	TAGAAAAAAGGAGGGTGTTATTCATGGAAGAAATATA
TTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	TGATGTAAGAGAAATGATGAAAGATGACGAAGTTGTA
TTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	CAAGAATTTAAAGATAACGAATTGAACGGGTTTATA
TTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC	ACAGGATTGTATCTTTTAATAGAGAACAACACTATTAA
TTCTCGTCCCCTGTTATTCGGGGTAGTTATCGATC

Protein	Signature genes	Signature genes Name	Protein_function
CP029649.1\|AWQ65836.1\|1730173_1730599_-\|hypothetical-protein	csm2gr11	cd09647_csm2gr11_CAS-III-A	gnl\|CDD\|273844
CP029649.1\|AWQ67031.1\|1724316_1724475_-\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ65713.1\|1729527_1730172_-\|RAMP-superfamily-protein	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
CP029649.1\|AWQ65495.1\|1736079_1736301_-\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ66108.1\|1725584_1726319_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|273848
CP029649.1\|AWQ67584.1\|1741546_1742656_-\|DNA-polymerase-A-family-protein	unknown	unknown	gnl\|CDD\|237876
CP029649.1\|AWQ67085.1\|1735784_1735916_+\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ66675.1\|1736833_1737145_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368760
CP029649.1\|AWQ67010.1\|1732888_1733194_-\|CRISPR-associated-endoribonuclease-Cas2	cas2	cd09638_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|273699
CP029649.1\|AWQ66718.1\|1741185_1741554_-\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ65454.1\|1737665_1739345_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|214861
CP029649.1\|AWQ65838.1\|1737238_1737577_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368749
CP029649.1\|AWQ67128.1\|1727583_1728606_-\|RAMP-superfamily-protein	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
CP029649.1\|AWQ65441.1\|1735527_1735788_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378743
CP029649.1\|AWQ65174.1\|1730601_1732875_-\|HD-domain-protein	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811
CP029649.1\|AWQ66896.1\|1728608_1729442_-\|putative-cRISPR-associated-RAMP-protein	csm4gr5	COG1567_csm4gr5_CAS-III-A	gnl\|CDD\|273866
CP029649.1\|AWQ66827.1\|1736315_1736819_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226783
CP029649.1\|AWQ66753.1\|1739569_1741186_-\|putative-cassette-chromosome-recombinase	unknown	unknown	gnl\|CDD\|225913
CP029649.1\|AWQ66292.1\|1726315_1727584_-\|CRISPR-associated-family-protein	csm6	cd09699_csm6_CAS-III-A	gnl\|CDD\|131720
CP029649.1\|AWQ65958.1\|1733193_1734099_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851

Protein	Function_ID	Function_description	E-value
CP029649.1\|AWQ65836.1\|1730173_1730599_-\|hypothetical-protein	gnl\|CDD\|273844	TIGR01870, CRISPR_type_III-associated_protein_Csm2, CRISPR type III-A/MTUBE-associated protein Csm2. These proteins are found adjacent to a characteristic short, palidromic repeat cluster termed CRISPR, a probable mobile DNA element. This model represents the C-terminal domain of a minor family of CRISPR-associated protein from the Mtube subtype of CRISPR/Cas locus. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2.	7.59929e-21
CP029649.1\|AWQ65713.1\|1729527_1730172_-\|RAMP-superfamily-protein	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	7.36094e-106
CP029649.1\|AWQ66675.1\|1736833_1737145_-\|hypothetical-protein	gnl\|CDD\|368760	pfam06124, DUF960, Staphylococcal protein of unknown function (DUF960). This family consists of several hypothetical proteins from several species of Staphylococcus. The function of this family is unknown.	6.74747e-26
CP029649.1\|AWQ66108.1\|1725584_1726319_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	7.10684e-15
CP029649.1\|AWQ67010.1\|1732888_1733194_-\|CRISPR-associated-endoribonuclease-Cas2	gnl\|CDD\|273699	TIGR01573, cas2, CRISPR-associated endonuclease Cas2. This model describes most members of the family of Cas2, one of the first four protein families found to mark prokaryotic genomes that contain multiple CRISPR elements. CRISPR systems protect against invasive nucleic acid sequences, including phage. Cas2 proteins have been characterized as either endoribonuclease (for ssRNA) or endodeoxyribonuclease (for dsDNA), depending on the system to which the Cas2 belongs. CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeats. The cas genes usually are found near the repeats. A distinct branch of the Cas2 family shows a very low level of sequence identity and is modeled by TIGR01873 instead of by this model (TIGR01573).	4.06918e-22
CP029649.1\|AWQ67584.1\|1741546_1742656_-\|DNA-polymerase-A-family-protein	gnl\|CDD\|237876	PRK14975, PRK14975, bifunctional 3'-5' exonuclease/DNA polymerase; Provisional.	1.53397e-08
CP029649.1\|AWQ65454.1\|1737665_1739345_-\|recombinase-family-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	6.7072e-34
CP029649.1\|AWQ65838.1\|1737238_1737577_-\|hypothetical-protein	gnl\|CDD\|368749	pfam06106, SAUGI, S. aureus uracil DNA glycosylase inhibitor. Uracil-DNA glycosylase inhibitors, are DNA mimic proteins that prevent the DNA binding sites of UDGs (Uracil DNA glycosylase) from interacting with their DNA substrate. SSP0047 (SAUGI; for Staphylococcus aureus uracil-DNA glycosylase inhibitor) acts as a uracil-DNA glycosylase inhibitor that breaks the uracil-removing activity of S. aureus uracil-DNA glycosylase (SAUDG) pfam03167. The SAUGI/SAUDG complex has been determined, and shows that SAUGI binds to the SAUDG DNA binding region via several strong interactions, by using a hydrophobic pocket to hold SAUDG's protruding residue (i.e. SAUDG Leu184, E. coli UDG Leu191 and B. subtilis UDG Phe191). By binding to SAUDG in this way, SAUGI thus prevents SAUDG from binding to its DNA substrate and performing DNA repair activity.	8.57061e-38
CP029649.1\|AWQ67128.1\|1727583_1728606_-\|RAMP-superfamily-protein	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	3.06095e-17
CP029649.1\|AWQ65441.1\|1735527_1735788_+\|hypothetical-protein	gnl\|CDD\|378743	pfam11867, DUF3387, Domain of unknown function (DUF3387). This domain is functionally uncharacterized. This domain is found in bacteria and archaea. This presumed domain is typically between 255 to 340 amino acids in length. This domain is found associated with pfam04851, pfam04313.	3.1971e-31
CP029649.1\|AWQ65174.1\|1730601_1732875_-\|HD-domain-protein	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0
CP029649.1\|AWQ66896.1\|1728608_1729442_-\|putative-cRISPR-associated-RAMP-protein	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	4.83771e-38
CP029649.1\|AWQ65958.1\|1733193_1734099_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.00185e-113
CP029649.1\|AWQ66753.1\|1739569_1741186_-\|putative-cassette-chromosome-recombinase	gnl\|CDD\|225913	COG3378, COG3378, Phage associated DNA primase [General function prediction only].	3.31891e-21
CP029649.1\|AWQ66292.1\|1726315_1727584_-\|CRISPR-associated-family-protein	gnl\|CDD\|131720	TIGR02672, hypothetical_protein_SERP2456, CRISPR type III-A/MTUBE-associated protein Csm6. Members of this family as found in CRISPR-associated (cas) gene regions in Streptococcus thermophilus CNRZ1066, Staphylococcus epidermidis RP62A, and Mycobacterium tuberculosis (strains CDC1551 and H37Rv), as part of Mtube-type CRISPR/Cas systems. CRISPR is a widespread form of direct repeat found in archaea and bacteria, with distinctive subtypes each of which has a characteristic sporadic distribution.	1.16357e-132
CP029649.1\|AWQ66827.1\|1736315_1736819_-\|hypothetical-protein	gnl\|CDD\|226783	COG4333, COG4333, Uncharacterized protein conserved in bacteria [Function unknown].	1.3268e-79

>CP029649.1|AWQ65958.1|1733193_1734099_-|CRISPR-associated-endonuclease-Cas1
MKDVIYVENHYFVTVKENSIKFRNVIDKSEKFYLFEEIEAIIFDHYKSYFSHKLVIKCIENDIAIIFCDKKHSPLTQLISSYGMTHRLQRIQSQFQLSGRTRDRIWKKIVVNKIINQSKCLENNLHNENVKLLVNLAKDVSSGDKSNKEAQAARIYFKDLYGKQFKRGRYNDIINSGLNYGYSILRSFIKKELALHGFEMSLGINHRSKENPFNLADDIIEVFRPFVDNIVYEIVFKKNINTFDVNEKKLLLNVLYEKCIIDKKVVRLLDSVKIVIQSLIRCYEENTPTYLLLPKMIEVGN
>CP029649.1|AWQ67010.1|1732888_1733194_-|CRISPR-associated-endoribonuclease-Cas2
MYLLVSFDLPRDTKFERRVASKYRTRLLELGFSMKQFSLYERYVSDVQKKDKILEILQQEIPDTGSITLYVLPDEVNNSQITILGKEVKVVVRKEPKLIFL
>CP029649.1|AWQ65174.1|1730601_1732875_-|HD-domain-protein
MDKKTTLMYGSLLHDIGKIIYRSNDHAFARGTHSKLGYNFLSQFSEFKDNEVLDSIAYHHYKELAKANLANDNTAYITYIADNIASGIDRRDVIEEGDEEYEKQAFNFDKYTPLYSVFNIVNSEKLKQISGKFKFSNESNIEYPKTENIQYSSGNYTTLMKDMSYDLEHKLSIKEDTFPSLLQWTESLWQYVPSSTNKNQLIDISLYDHSRITCAIASCIFDYLNENNIHNYKDELFTKYENTKEFYQKEAFLLLSMDMSGIQDFIYNISGSKALKSLRSRSFYLEIMLEVIVDQLLEKLELTRANLLYTGGGHAYLLVSNTDKGKEKINQFNTELKNWFMSEFTTDLSLSIAFEKCSGNDLMNTSGNYRNIWRNVSSKLSDIKAHKYSSEDILKLNHFHSYGDRECKECLRSDIDINDDGLCSICEGIINISNDLRDKSFFVLSETGKLKMPFDKFISVIDYEEAERLAQNNNHIRIYSKNKPYIGVGISTNLWMCDYDYASQNKDMREKGIGSYVEREEGIKRLGVVRADIDNLGATFISGIPEKYNSISRTATLSRQLSLFFKYELNHLLENYQITAIYSGGDDLFLIGAWDDIIEVSVYINEKFKDFTLGKLTMSAGVGMFSGKYPISKMAFETGLLEEAAKTDEKNQIALWVQEKVYNWDEFKKYILEEKLLVLQHGFSQTDEHGKAFIYKMLALLRNNETINIARLAYLLARSKMTEEFTSKIFNWAQNDKDKNQLITALEYYVYQIREVD
>CP029649.1|AWQ65836.1|1730173_1730599_-|hypothetical-protein
MILAKTKSGKKIDLTFAHEVVKSNVKTVKDKRGKENQVLFNGLTTSKLRNLMEQVNRLYTIAFNSTEDQLNEEFIDELEYLKIKFYYEAGREKSVDEFLKKTLMFPIIDRVIQKESKKFFLDYCKYFEALVAYAKYYQKED
>CP029649.1|AWQ65713.1|1729527_1730172_-|RAMP-superfamily-protein
MYSKIKISGTIEVVTGLHIGGGGESSMIGAIDSPVVRDLQTKLPIIPGSSIKGKMRSLLAKHFGLKMKQENHNQDDESVLRLFGSSEKGNIQRARLQISDAFFSEKTKEHFAQNDIAYTETKFENTINRLTAVANPRQIERVTRGSEFDFVFIYNVDEESQVENDFENIEKAIHLLENDYLGGGGTRGNGRIQFNDITIETVVGEYDSTNLKIK
>CP029649.1|AWQ66896.1|1728608_1729442_-|putative-cRISPR-associated-RAMP-protein
MTITSDTLFSALFIEALQLGIETDWLLNDLIISDTFPYENEIYYLPKPLIKIESKEEGNHKAFKKLKYVPVHHYNQYLNGELSAEDATDLNDIFSIGHFSLQTKVSLSAQEIDSSADSEPYSVGTFTFEPEAGLYFIAKGSEETLDQLKDIMTSLQYSGLGGKRNAGYGQFEYEIINNQQLFKLLNQNGEHSILLSTAMAKEDEIKSALKEARYILNKRSGFIQSTNYSEMLVKKSDFYSFSSGSVFKNIFNGDVFNVGHNGKHPVYRYAKPLWLEV
>CP029649.1|AWQ67128.1|1727583_1728606_-|RAMP-superfamily-protein
MTIKNYEVVIKTLGPVHIGSGQVMKKQDYIYDFYNSKVYMINGNKLVKFLKRKNILDTYQNFLRYPPKNPRENGLKDYLDAQNVKQSEWKAFVSYSEKVNQGKKYGNIRPKPLNDLHLMVRDGQNKVYLPGSSIKGAIKTALVSKYNNEKNTDVYSKIKVSDSEPIDERHLAIYQKIDINKSEKPMPLYRECVDVDTEIKFKLTIEDEIYSINEIEQSIQDFYKNYYDKWLVGFKETKGGRRFALEGGMPDVLNQNILFLGAGAGFVSKTTHYQLKSREQAKRDSFDILTKKFRRTYGKMKEMPSNVPVALKGTTNQSLHVSYQQGMCKISFQELNNEVL
>CP029649.1|AWQ66292.1|1726315_1727584_-|CRISPR-associated-family-protein
MKVLFSPIGNSDPWSNDRDGAMLHIVRHYKPDVVVLFFTESIWNGNRNIPGRKNFDWENIVSKVSSRTKVDIKVDSIKYENDFDSYKDIFHFYINEIRTKYSDAEILLNVTSGTPQMESTLCLEYISNPHNMKCIQVSTPAPIEGPKRSFAKLETVTEDLNKVNANEKMASNRSKSINIISFREVMVRSQIKSLVNNYDYEGALNLVSDQKSFRNGKLLRKRLLELTNQIKTHEVFPEINDKYRSVALKKSLFHYLLLNMRYNRLDVAETLIRVKSIAEFILKTYIVGHWPTLIIEKDDKPYLNAEDNLSFIYKYKLLLEKRRQNLDVSRILGLPAFIDILTVLEPNSKLLKEVNAVNDINGLRNSIAHNLETLDLDKNKNYKKIMLSVEAIKNMLHISFPEIEEKDYNYFERKNKEFRELL
>CP029649.1|AWQ66108.1|1725584_1726319_-|CRISPR-associated-endoribonuclease-Cas6
MINKITVELDLPDSIRFQYLGSILHGVLMDYLPNDIADQLHHEFAYSPLKQRIYHKNKKVIWEIVCMSDRLFNEIAELFTSKNRLFLKYYQVYIEIYSFNIEKVNVQNIMNQLLETEELNRYVRINIQTPMSFKYQSNYMIFPEVKRFFRSIMIQFDAFFEEYKMYDKETLDFLEKNINIVDYKLKSTRFNLEKVKIPSFTGEIVFKIKGPLPFLQLTHFLLKFGEFSGSGMKTSLGMGKYSII
>CP029649.1|AWQ67031.1|1724316_1724475_-|hypothetical-protein
MKFKSKQLVIANQTKVINYRIQVLLKPQANIETQTQVKNNTLPETDEQSNAD
>CP029649.1|AWQ65441.1|1735527_1735788_+|hypothetical-protein
MAVELLNRLLKGQVKSLMKTNATVSKRFSEMLRNSINKYNSRSIETSKVIEELIQLAKDIKQEQQRGNELGLNSDEIAFLRCFSFT
>CP029649.1|AWQ67085.1|1735784_1735916_+|hypothetical-protein
MKQRKKGMEDEELRAIAHELTKKVKENMGVIGLNVIAQKLKCA
>CP029649.1|AWQ65495.1|1736079_1736301_-|hypothetical-protein
MNHETTHSDWRTVANCLASQNYISIVKGLVHHFTAIEDEEILDKIYEDFMNNGSITTVLNNDLQDIINYYLSK
>CP029649.1|AWQ66827.1|1736315_1736819_-|hypothetical-protein
MNTIKSTIHTEAIFSDDEQHRYLLKKTWDEKKPVCTVITMYPHLDGVLSLDLTTVLILNQLANSEQYGAVYLVNLFSNIKTPENLKHIKEPYDKHTDIHLMKAISESDTVILAYGAYAKRPVVVERVEQVMEMLKPHKKKVKKLINPATNDIMHPLNPKARQKWILK
>CP029649.1|AWQ66675.1|1736833_1737145_-|hypothetical-protein
MNINRYITRGISEQLSLDLQILLWHMVEEKDNQPHTDYLHIFKLQEDDNMLSITHEQEQPAYKLEYHYINYEKNQNALPKKVYVIREDDVDVFYYVMLLPEEY
>CP029649.1|AWQ65838.1|1737238_1737577_-|hypothetical-protein
MTLSKQLKTYITERFKLNYQETWACETIDAVAEDVLPEKYIKNSPLEHKILNTFTYYNDELHEISIYPFLCYLDKELVAIGYLDNFDLDFIFLNDTHQIIIDERYLLQKGGE
>CP029649.1|AWQ65454.1|1737665_1739345_-|recombinase-family-protein
MKGKIALYSRVSTSEQSEHGYSEKEQEQLLIKEVMKNFPGYDYETYTDSGISGKNIEGRPAMKRLLQDVKDNKIEMVLSWKLNRISRSMRDVFNIIHEFKEHDVGYKSISENIDTSNASGEVLVTMFGLIGSIERQTLISNVKLSMNAKARSGEAITGRVLGYKLSLNPLTQKNDLVIDENEAHIVREIFDLYLNHNKGFKAITTILNQKGYRTINQKPFSVFGVKYILNNPVYKGYVRFNNHQNWAVQRRSGKSDKNDVILVKGKHEAIISEDVFDQVHEKLASKSFKPGRPIGGDFYLRGLIKCPECGNNMVCRRTYYKTKKSKERTIKRYYICSLFNRSGSSACHSNAINAEVVERVINVHLNRILSQPNVIKQIASSVIEELKQKHSKQTEIKYDIDSLEKQKAKVKTQQERLLELFLDDEMDSEMLKAKQSEMNQQLEVLDQQIKEAKQANQSQDDIPNFDKLKARLILMITRFSVYLRKATPEAKNQLMKMLIDSIEITTDKQVKLVRYKIDESLIPQSLKKDWGSFFIPKFNFVINVTKKNRIENLSLLPLF
>CP029649.1|AWQ66753.1|1739569_1741186_-|putative-cassette-chromosome-recombinase
MNHILEMLIKLLKVGMEAIDRKGLIAILTSSIGNDEMDDSEQAVMVYNELIDKLQLNIPKDVDYRPNIYSYFGIQKKPNDTILVEMMICIFHIKRFDSELFVFKDKGWQKVSEDELQGLISKMIQVLLVDYKPSLSTLKNVVDGIQKSTDIEKLVEHRQYIGCGRNMFNLKTFKVVDNDLEIFPKTRLDLELDINDTITDKIPPNFKQYMLELANYDHDLQYFLFQHMAVLLTADTKLRRGLFLYGTAKNGKSVYIKLVKSFFYSNDIVSKTLNELGGRFDKESLIGKRIMASDEVGKANIDEATVNDFKKLLSVEPIHADRKGRTQVEVTLDLKLIFNTNAVLNFPSSHAKALERRIAVIPCEYYVEKADPDLIEKLQDEKKEIFLYLMYVYKQIVKNDIEYLQNDRVTEISHDWLNFGYEFVSSKSANIAHQKACINLLRKLIEIKPGSRIKVSRLNEVIRDEIKVSSQVINDLVQANFNVQSRLNNGYKYWVDLGWKETDKKDDMISFDKNENVTDDEFLYEDDLNLGWEDFDDE
>CP029649.1|AWQ66718.1|1741185_1741554_-|hypothetical-protein
MNNDRGKSLQIPQSTLLKEGSIYVATLHSVYEKNFSGDIKHQFTYEVELNQETHYVNRNITVKSMSHQLSIADWIKRHSNYNVNHINYDPYIDRKHLVLVGQYNGNYYIQDVAPLDEFGGVL
>CP029649.1|AWQ67584.1|1741546_1742656_-|DNA-polymerase-A-family-protein
MYQANIRDLITKLPQSNKTEHFLMNKFSNQDKVQQLQRQISQQLDQQYNELLANEKAKLDQYVEVHHNLEPLKKEIESESINLDTDKLPDIKATMLEKAKNDEHFDKIEQLFDRLDQSLNGTNRLYTQLSLIGTRTHRITTKRFNVQGLPKLVQQMILPSQFKKVYTIDFKSFEPSVAAYMTQDEQLIDYLNHEEGLYDALLRDLSLSKEKRVSVKRAFIGSFLFGGRYSSSKFKINQEVSEINWLQVMSKFKKVIEFKEQVEKYKTMPTPYGIEHDMSAFQGSSIMAIYVQTVASYIFKHILLEVYKAQCEKKTFKIIVPIHDAIMIECNDKGIAQNVAQLMKDTANQLFNGEFAHVTVEALGGIDNE

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Crispr_ID: CP029649_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029649_10

2127128-2127225

Orphan

Consensus_repeat	Method
GCCTTTCTAGCTCATAAAATTCGCAGAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP029649_10

>merge|CP029649|10|2127128-2127225|CRISPRCasFinder
GCCTTTCTAGCTCATAAAATTCGCAGAAAATAAAGGAACGCATTAGATAGCTTCGCTACTAATGCATAAGCCTTTCTAGCTCATAAAATTCGCAGAAA

>CP029649|10|9|2127128-2127225|CRISPRCasFinder
GCCTTTCTAGCTCATAAAATTCGCAGAAA	ATAAAGGAACGCATTAGATAGCTTCGCTACTAATGCATAA
GCCTTTCTAGCTCATAAAATTCGCAGAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP029649.1\|AWQ66300.1\|2116650_2118009_+\|adenosylmethionine-8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
CP029649.1\|AWQ66888.1\|2122322_2123270_-\|gamma-hemolysin-component-C	unknown	unknown	gnl\|CDD\|369625
CP029649.1\|AWQ66828.1\|2123837_2124767_-\|gamma-hemolysin-component-A	unknown	unknown	gnl\|CDD\|369625
CP029649.1\|AWQ66351.1\|2127364_2128231_+\|cation-diffusion-facilitator-transporter-family-protein	unknown	unknown	gnl\|CDD\|223131
CP029649.1\|AWQ65610.1\|2135044_2135407_+\|putative-lipoprotein	unknown	unknown	gnl\|CDD\|291399
CP029649.1\|AWQ65601.1\|2121343_2122321_-\|gamma-hemolysin-component-B	unknown	unknown	gnl\|CDD\|273388
CP029649.1\|AWQ67627.1\|2120824_2121292_+\|queT-transporter-family-protein	unknown	unknown	gnl\|CDD\|377623
CP029649.1\|AWQ67553.1\|2125301_2126612_-\|immunoglobulin-binding-protein-sbi	unknown	unknown	gnl\|CDD\|288473
CP029649.1\|AWQ65468.1\|2131995_2132715_+\|L-cystine-transport-system-permease-protein-TcyB	unknown	unknown	gnl\|CDD\|223836
CP029649.1\|AWQ65679.1\|2118010_2119018_+\|biotin-synthase	unknown	unknown	gnl\|CDD\|235755
CP029649.1\|AWQ65160.1\|2129675_2131115_+\|H+-antiporter-2-family-protein	unknown	unknown	gnl\|CDD\|129794
CP029649.1\|AWQ65360.1\|2135425_2136025_+\|DSBA-like-thioredoxin-domain-protein	unknown	unknown	gnl\|CDD\|224565
CP029649.1\|AWQ67122.1\|2115986_2116673_+\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|223210
CP029649.1\|AWQ66532.1\|2132711_2133443_+\|ABC-transporter-family-protein	unknown	unknown	gnl\|CDD\|224051
CP029649.1\|AWQ66883.1\|2120121_2120814_+\|6-carboxyhexanoate--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|224342
CP029649.1\|AWQ67724.1\|2133539_2134790_-\|femAB-family-protein	unknown	unknown	gnl\|CDD\|367067
CP029649.1\|AWQ67596.1\|2131235_2132015_+\|bacterial-extracellular-solute-binding,-3-family-protein	unknown	unknown	gnl\|CDD\|270429
CP029649.1\|AWQ67001.1\|2136297_2136549_+\|antitoxin-YefM	unknown	unknown	gnl\|CDD\|225072
CP029649.1\|AWQ65639.1\|2118998_2120111_+\|aminotransferase-class-V-family-protein	unknown	unknown	gnl\|CDD\|223234
CP029649.1\|AWQ67322.1\|2128557_2129244_+\|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|184518

Protein	Function_ID	Function_description	E-value
CP029649.1\|AWQ66300.1\|2116650_2118009_+\|adenosylmethionine-8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
CP029649.1\|AWQ66888.1\|2122322_2123270_-\|gamma-hemolysin-component-C	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	7.97441e-93
CP029649.1\|AWQ66828.1\|2123837_2124767_-\|gamma-hemolysin-component-A	gnl\|CDD\|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	4.31899e-97
CP029649.1\|AWQ66351.1\|2127364_2128231_+\|cation-diffusion-facilitator-transporter-family-protein	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	2.54055e-90
CP029649.1\|AWQ65610.1\|2135044_2135407_+\|putative-lipoprotein	gnl\|CDD\|291399	pfam14729, DUF4467, Domain of unknown function with cystatin-like fold (DUF4467). Large family of predicted lipoproteins from Gram-positive bacteria Experimentally determined structure shows a cystatitin-like fold, allowing us to classify this family in the NFT2 clan, despite lack of any detectable sequence similarity between members of this family and other families in this clan.	3.11961e-31
CP029649.1\|AWQ65601.1\|2121343_2122321_-\|gamma-hemolysin-component-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	5.50766e-128
CP029649.1\|AWQ67627.1\|2120824_2121292_+\|queT-transporter-family-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00158559
CP029649.1\|AWQ67553.1\|2125301_2126612_-\|immunoglobulin-binding-protein-sbi	gnl\|CDD\|288473	pfam11621, Sbi-IV, C3 binding domain 4 of IgG-bind protein SBI. This family of proteins represents Sbi domain IV which binds the central complement protein C3. Sbi-IV interacts with Sbi-III to induce a consumption of complement via alternative pathway activation. When not interacting with Sbi-III, Sbi-IV inhibits the alternative pathway without complement consumption. The structure of Sbi-IV consists of a three-helix bundle fold.	1.70632e-25
CP029649.1\|AWQ65468.1\|2131995_2132715_+\|L-cystine-transport-system-permease-protein-TcyB	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	4.98247e-78
CP029649.1\|AWQ65679.1\|2118010_2119018_+\|biotin-synthase	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
CP029649.1\|AWQ65160.1\|2129675_2131115_+\|H+-antiporter-2-family-protein	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.41176e-92
CP029649.1\|AWQ65360.1\|2135425_2136025_+\|DSBA-like-thioredoxin-domain-protein	gnl\|CDD\|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	2.24775e-30
CP029649.1\|AWQ67122.1\|2115986_2116673_+\|dethiobiotin-synthase	gnl\|CDD\|223210	COG0132, BioD, Dethiobiotin synthetase [Coenzyme metabolism].	1.45777e-70
CP029649.1\|AWQ66532.1\|2132711_2133443_+\|ABC-transporter-family-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	3.20826e-144
CP029649.1\|AWQ66883.1\|2120121_2120814_+\|6-carboxyhexanoate--CoA-ligase-family-protein	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	2.9803e-130
CP029649.1\|AWQ67724.1\|2133539_2134790_-\|femAB-family-protein	gnl\|CDD\|367067	pfam02388, FemAB, FemAB family. The femAB operon codes for two nearly identical approximately 50-kDa proteins involved in the formation of the Staphylococcal pentaglycine interpeptide bridge in peptidoglycan. These proteins are also considered as a factor influencing the level of methicillin resistance.	0
CP029649.1\|AWQ67596.1\|2131235_2132015_+\|bacterial-extracellular-solute-binding,-3-family-protein	gnl\|CDD\|270429	cd13711, PBP2_Ngo0372_TcyA, Substrate binding domain of ABC transporters involved in cystine import; the type 2 periplasmic binding protein fold. This subgroup includes cystine-binding domain of periplasmic receptor-dependent ATP-binding cassette transporters from Neisseria gonorrhoeae and Bacillus subtilis and their related proteins. Cystine is an oxidized dimeric form of cysteine that is required for optimal bacterial growth. In Bacillus subtilis, three ABC transporters, TcyJKLMN (YtmJKLMN), TcyABC (YckKJI), and YxeMNO are involved in uptake of cystine. Likewise, three uptake systems were identified in Salmonella enterica serovar Typhimurium, while in Escherichia coli, two transport systems seem to be involved in cystine uptake. Moreover, L-cystine limitation was shown to prevent virulence of Neisseria gonorrhoeae; thus, its L-cystine solute receptor (Ngo0372) may be suited as target for an antimicrobial vaccine. The cystine receptor belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.11829e-100
CP029649.1\|AWQ67001.1\|2136297_2136549_+\|antitoxin-YefM	gnl\|CDD\|225072	COG2161, StbD, Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning].	5.66738e-21
CP029649.1\|AWQ65639.1\|2118998_2120111_+\|aminotransferase-class-V-family-protein	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	6.17916e-138
CP029649.1\|AWQ67322.1\|2128557_2129244_+\|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase	gnl\|CDD\|184518	PRK14119, gpmA, phosphoglyceromutase; Provisional.	3.52864e-167

>CP029649.1|AWQ67553.1|2125301_2126612_-|immunoglobulin-binding-protein-sbi
MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQNNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVAQQNAFYNVLKNDNLTEQEKNNYIAQIKENPDKSQQVWVESVQSSKAKERQNIENADKAIKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAITKLQKNDSIENRRLAQREVNKAPMDVKEHLQKQLDALVAQKDAEKKVAPKVEAPQIQSPQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEKYDTAKYYTDKYFKYKGTIDKTVLSVFGNGYKSYIQPLKVEDQKNYVSKSYAQVRNYVTETLNTGKVLYAFYQNPKVVKAAITTAETASSIKNTLSNLLSFWK
>CP029649.1|AWQ66828.1|2123837_2124767_-|gamma-hemolysin-component-A
MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK
>CP029649.1|AWQ66888.1|2122322_2123270_-|gamma-hemolysin-component-C
MLKNKILATTLSVSLLAPLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFATESGQKSAFDSDLFVGYKPHSKDPRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSSDTSEFEITYGRNMDVTHAIKRSTHYGNSYLDGHRVHNAFVNRNYTVKYEVNWKTHEIKVKGQN
>CP029649.1|AWQ65601.1|2121343_2122321_-|gamma-hemolysin-component-B
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
>CP029649.1|AWQ67627.1|2120824_2121292_+|queT-transporter-family-protein
MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSLLLLIFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLASVLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTMRKRMAVLLR
>CP029649.1|AWQ66883.1|2120121_2120814_+|6-carboxyhexanoate--CoA-ligase-family-protein
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDNRIDLNHYISFLESTPKQVVYETV
>CP029649.1|AWQ65639.1|2118998_2120111_+|aminotransferase-class-V-family-protein
MFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLAEYPNQNIQKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGIDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED
>CP029649.1|AWQ65679.1|2118010_2119018_+|biotin-synthase
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
>CP029649.1|AWQ66300.1|2116650_2118009_+|adenosylmethionine-8-amino-7-oxononanoate-transaminase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEEAIIIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEMMTAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYNAFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKRKLLSHIESTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRKCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDRKC
>CP029649.1|AWQ67122.1|2115986_2116673_+|dethiobiotin-synthase
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAFKMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDYVNQNVSASNFLIMNRYTDSYIEKDNQITIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT
>CP029649.1|AWQ66351.1|2127364_2128231_+|cation-diffusion-facilitator-transporter-family-protein
MSHNENLKLAQRGAYLSLIVYIILSIVKYVTGFVFNSAAVRADALNNMTDIIVSLAVIIGLKISIKPADRNHPYGHLKSENISSLLVSFVIMFVGIQVVIQNAPRLFKEDDVVPNAITIIVSLISGLVMLIVFAVNQRLAKRTKSSSLNSAAKDNLSDSLVSIGTAIGLIFTQIGFPIVDIILATLLGLLIVYTGFGIFKEAIFMLSDGFNETELEAYRNDILEVDEVQEVKSIKGRYHGSSVFIDVTIVVDANLSLVEAHQICDNVEHHLHKKGISSVYVHPEPDHL
>CP029649.1|AWQ67322.1|2128557_2129244_+|2,3-bisphosphoglycerate-dependent-phosphoglycerate-mutase
MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVRENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDARKEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVIPFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTDDLEVIDKYYL
>CP029649.1|AWQ65160.1|2129675_2131115_+|H+-antiporter-2-family-protein
MSKKQKLTMIITMLMGGFFGLLNETLLVTALPSIMKDFEISYTQVQWLTTAFLLTNGIVIPLSALVIQRYTTRQVFLVGISIFFLGTLLGGLSPHFATLLVARIIQALGAGIMMPLMMTTILDVFQPHERGKYMGIFGLVIGLAPAIGPTLSGYLVEYFNWRSLFHVVAPIAAVTFLIGFKTIKNVGTTIKVPIDFISVIFSVLGFGGLLYGTSSISEKGFDNPIVLVSMIGGVVLVALFVLRQYRLSTPLLNFAVFKNKQFTVGIIIMGVTMVSMIGSETILPIFVQNLLHRSALDSGLTLLPGAIVMAFMSMTSGALYEKFGPRKLALVGMAIVVITTAYFVVMDEQTSTIMLATVYAIRMVGIALGLIPVMTHTMNQLKPEMNAHGSSMTNTVQQIAGSIGTAALITILSHASKNFSPTMSDYNGMNKIDMMNQIKVDTMLHGYHAGFLFALLITVVSFFCSFMLQGKKKEVDSRQ
>CP029649.1|AWQ67596.1|2131235_2132015_+|bacterial-extracellular-solute-binding,-3-family-protein
MKRLLFVMIAFVFILAACGNNSSKDKEANKDSKTINVGTEGTYAPFSFHDKDGKLTGYDIDVIKAVAKEEGLKLKFNETSWDSMFAGLDAGRFDVIANQVGINPDREKKYKFSKPYTFSSAVLVIRENEKDIKDFDDVKGKKLAQTFTSNYGKLAKDKGADITKVDGFNQSMDLLLSKRVDGTFNDSLSYLDYKKQKPNAKIKAIKGNAEQSRSAFAFSKKADDETVQKFNDGLKKIEENGELAKIGKKWFGQDVSKSK
>CP029649.1|AWQ65468.1|2131995_2132715_+|L-cystine-transport-system-permease-protein-TcyB
MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
>CP029649.1|AWQ66532.1|2132711_2133443_+|ABC-transporter-family-protein
MIQLNNIHKSFNDVEVIKGIDLSVEQGEVVTLIGRSGSGKTTLLRMINALEIPTEGTVYVNGKTYTSKDKKSQIEVRKQSGMVFQSYNLFPHKTALENVMEGLITVKKLKKDEARGKSLELLEKVGLTHVKDQRPHALSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVNDVLKVIKDLANEGMTMVIVTHEMRFAKEVSNNIVFIHEGMIGEQGAPEEMFNRPKTEELRRFLNVINEE
>CP029649.1|AWQ67724.1|2133539_2134790_-|femAB-family-protein
MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGVKDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKHNCLYVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDTLGYKHQGFPVGYDSMSQIRWLSVLDLKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKFRELPYFEEMQKLYDDHAMLKLAYIDLNEYLKTLQLKQQQLTAELSGVEEALKESPNSKKNKTKRTQLEQQLNSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPKYNAYMGAYHLQWEMIKFAKAHHIDRYNFYGITGDFSESSEDYGVQQFKKGFNAHVEEYIGDFIKPIKPMFYKIQQYLNHKRR
>CP029649.1|AWQ65610.1|2135044_2135407_+|putative-lipoprotein
MKRFVATVLLLLVFISGCGNDKYVKEIDEAVKIQNQKQEQLAKKGNGDRVDHFERKDANIYVYDKDKIIILAYKPLSNDDEVHYYAYDFSDKRVSYKQDFDSRRYYQQHDADYHEENMTN
>CP029649.1|AWQ65360.1|2135425_2136025_+|DSBA-like-thioredoxin-domain-protein
MTKKLLTLFIVSMLILTACGKKESATTSSKNGKPLVVIYGDYKCPFCKELDEKVMPKLRKNYIDNHKVEYQFVNLAFLGKDSIVGSRASHAVLMYAPKSFLDFQKQLFAAQQDENKEWLTKELLDKHIKQLHLDKETENKIIKDYKTKDSKSWKAAEKDKKIAKDNHIKTTPTAFINGEKVEDPYDYESYEKLLKDKIK
>CP029649.1|AWQ67001.1|2136297_2136549_+|antitoxin-YefM
MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESDYNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKDIDV

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Click the colored protein region to show detailed information

Crispr_ID: CP029649_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP029649_11

2635817-2635948

Orphan

Consensus_repeat	Method
CAGGTTGGCGGGGCCCCAACAAAGAGAA	PILER-CR
CAGGTTGGCGGGGCCCCAACACAGA	CRISPRCasFinder

2 spacers

DEDDh

The CRISPR arrays of CP029649_11

>merge|CP029649|11|2635817-2635948|PILER-CR,CRISPRCasFinder
CGGGGCCCCAACAAAGAGAATTTCAAAAAAGAAATTCTACAGGCAATACAGGTTGGCGGGGCCCCAACACAGAAGCTGACGAAAAGTCAGCTTACGATAATGTGCAGGTTGGCGGGGCCCCAACATAGAGAA

>CP029649|11|4|2635817-2635948|PILER-CR
CGGGGCCCCAACAAAGAGAATTTCAAAA	AAGAAATTCTACAGGCAATACAGGTTGG
CGGGGCCCCAACACAGAAGCTGACGAAA	AGTCAGCTTACGATAATGTGCAGGTTGGCGG
GGCCCCAACATAGAGAA

>CP029649|11|10|2635865-2635945|CRISPRCasFinder
CAGGTTGGCGGGGCCCCAACACAGA	AGCTGACGAAAAGTCAGCTTACGATAATGTG
CAGGTTGGCGGGGCCCCAACATAGA

Protein	Signature genes	Signature genes Name	Protein_function
CP029649.1\|AWQ65994.1\|2631494_2632808_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223840
CP029649.1\|AWQ65381.1\|2630702_2631203_-\|ferritin	unknown	unknown	gnl\|CDD\|224445
CP029649.1\|AWQ65273.1\|2633726_2634179_+\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ66004.1\|2637098_2637485_+\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ66526.1\|2628621_2629692_+\|impB/mucB/samB-family-protein	unknown	unknown	gnl\|CDD\|235035
CP029649.1\|AWQ65288.1\|2636123_2636882_+\|methionine-aminopeptidase,-type-I	unknown	unknown	gnl\|CDD\|235576
CP029649.1\|AWQ66672.1\|2641466_2641742_-\|hypothetical-protein	unknown	unknown	unknown
CP029649.1\|AWQ65726.1\|2642571_2643819_+\|thermophilic-metalloprotease-family-protein	unknown	unknown	gnl\|CDD\|376723
CP029649.1\|AWQ66930.1\|2637499_2638201_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227100
CP029649.1\|AWQ67512.1\|2632809_2633541_+\|cobB/CobQ-like-glutamine-amidotransferase-domain-protein	unknown	unknown	gnl\|CDD\|225974
CP029649.1\|AWQ66179.1\|2642359_2642560_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227177
CP029649.1\|AWQ65719.1\|2639230_2639860_+\|response-regulator	unknown	unknown	gnl\|CDD\|225107
CP029649.1\|AWQ66882.1\|2627844_2628375_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378690
CP029649.1\|AWQ67443.1\|2641748_2642213_-\|low-molecular-weight-protein-tyrosine-phosphatase-PtpA	unknown	unknown	gnl\|CDD\|319971
CP029649.1\|AWQ66714.1\|2639971_2641189_-\|yihY-family-inner-membrane-domain-protein	unknown	unknown	gnl\|CDD\|224214
CP029649.1\|AWQ67428.1\|2625285_2626233_+\|diacylglycerol-kinase	unknown	unknown	gnl\|CDD\|183982
CP029649.1\|AWQ66027.1\|2629758_2630313_-\|exonuclease-family-protein	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|99834
CP029649.1\|AWQ66002.1\|2634609_2635596_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226614
CP029649.1\|AWQ65800.1\|2638197_2639241_+\|sensor-protein-VraS	unknown	unknown	gnl\|CDD\|226951
CP029649.1\|AWQ66205.1\|2626313_2627675_+\|23S-rRNA-(uracil-5-)-methyltransferase-RumA	unknown	unknown	gnl\|CDD\|225174

Protein	Function_ID	Function_description	E-value
CP029649.1\|AWQ65994.1\|2631494_2632808_+\|hypothetical-protein	gnl\|CDD\|223840	COG0769, MurE, UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane].	3.73279e-99
CP029649.1\|AWQ65381.1\|2630702_2631203_-\|ferritin	gnl\|CDD\|224445	COG1528, Ftn, Ferritin-like protein [Inorganic ion transport and metabolism].	4.6035e-74
CP029649.1\|AWQ66526.1\|2628621_2629692_+\|impB/mucB/samB-family-protein	gnl\|CDD\|235035	PRK02406, PRK02406, DNA polymerase IV; Validated.	0
CP029649.1\|AWQ65288.1\|2636123_2636882_+\|methionine-aminopeptidase,-type-I	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.9498e-126
CP029649.1\|AWQ65726.1\|2642571_2643819_+\|thermophilic-metalloprotease-family-protein	gnl\|CDD\|376723	pfam02073, Peptidase_M29, Thermophilic metalloprotease (M29).	0
CP029649.1\|AWQ66930.1\|2637499_2638201_+\|hypothetical-protein	gnl\|CDD\|227100	COG4758, COG4758, Predicted membrane protein [Function unknown].	9.42019e-79
CP029649.1\|AWQ67512.1\|2632809_2633541_+\|cobB/CobQ-like-glutamine-amidotransferase-domain-protein	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	2.14444e-120
CP029649.1\|AWQ66179.1\|2642359_2642560_+\|hypothetical-protein	gnl\|CDD\|227177	COG4840, COG4840, Uncharacterized protein conserved in bacteria [Function unknown].	9.24488e-25
CP029649.1\|AWQ65719.1\|2639230_2639860_+\|response-regulator	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	2.91794e-79
CP029649.1\|AWQ66882.1\|2627844_2628375_+\|hypothetical-protein	gnl\|CDD\|378690	pfam11667, DUF3267, Putative zincin peptidase. This family of proteins has a conserved HEXXH motif, suggesting the members are putative peptidases of zincin fold.	1.4991e-11
CP029649.1\|AWQ67443.1\|2641748_2642213_-\|low-molecular-weight-protein-tyrosine-phosphatase-PtpA	gnl\|CDD\|319971	cd16343, LMWPTP, Low molecular weight protein tyrosine phosphatase. Low molecular weight protein tyrosine phosphatases (LMW-PTP) are a family of small soluble single-domain enzymes that are characterized by a highly conserved active site motif (V/I)CXGNXCRS and share no sequence similarity with other types of protein tyrosine phosphatases (PTPs). LMW-PTPs play important roles in many biological processes and are widely distributed in prokaryotes and eukaryotes.	3.39151e-65
CP029649.1\|AWQ66714.1\|2639971_2641189_-\|yihY-family-inner-membrane-domain-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	3.59491e-85
CP029649.1\|AWQ67428.1\|2625285_2626233_+\|diacylglycerol-kinase	gnl\|CDD\|183982	PRK13337, PRK13337, putative lipid kinase; Reviewed.	0
CP029649.1\|AWQ66027.1\|2629758_2630313_-\|exonuclease-family-protein	gnl\|CDD\|99834	cd06130, DNA_pol_III_epsilon_like, an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III. This subfamily is composed of uncharacterized bacterial proteins with similarity to the epsilon subunit of DNA polymerase III (Pol III), a multisubunit polymerase which is the main DNA replicating enzyme in bacteria, functioning as the chromosomal replicase. The Pol III holoenzyme is a complex of ten different subunits, three of which (alpha, epsilon, and theta) compose the catalytic core. The Pol III epsilon subunit, encoded by the dnaQ gene, is a DEDDh-type 3'-5' exonuclease which is responsible for the proofreading activity of the polymerase, increasing the fidelity of DNA synthesis. It contains three conserved sequence motifs termed ExoI, ExoII and ExoIII, with a specific Hx(4)D conserved pattern at ExoIII. These motifs are clustered around the active site and contain four conserved acidic residues that serve as ligands for the two metal ions required for catalysis. The epsilon subunit of Pol III also functions as a stabilizer of the holoenzyme complex.	4.39188e-75
CP029649.1\|AWQ66002.1\|2634609_2635596_-\|hypothetical-protein	gnl\|CDD\|226614	COG4129, COG4129, Predicted membrane protein [Function unknown].	5.31001e-76
CP029649.1\|AWQ65800.1\|2638197_2639241_+\|sensor-protein-VraS	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	6.78722e-72
CP029649.1\|AWQ66205.1\|2626313_2627675_+\|23S-rRNA-(uracil-5-)-methyltransferase-RumA	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	0

>CP029649.1|AWQ66002.1|2634609_2635596_-|hypothetical-protein
MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVVTIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKLQVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEEKLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYHKKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKDIFYDGSFKREDDSVETLRSTIKALEISGENQIKSHLLYEVLMIYRLLDSRYA
>CP029649.1|AWQ65273.1|2633726_2634179_+|hypothetical-protein
MQHEKMNDERNLTMKPTKVILRDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATFEDQEVKFEFALFDSDMDNLKHMDYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDSGLRHSNMATESGISLRINVAKSDFTKFINELASLY
>CP029649.1|AWQ67512.1|2632809_2633541_+|cobB/CobQ-like-glutamine-amidotransferase-domain-protein
MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINETEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGKKYITPDGTELEGLGILDFYTESKTNRLTGDIIIESDTFGTIVGFENHGGRTFHDFGTLGHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPKEIDNEAEIQAKQVLIDRANRQKKSR
>CP029649.1|AWQ65994.1|2631494_2632808_+|hypothetical-protein
MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLAEQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKTKIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKLLLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQIGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYSVLRELGLNEQTIKNGFETYTSDNGRMQYFKKEQKEAMINLAKNPAGMNASLSVGEQLEGEKVYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPIIVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS
>CP029649.1|AWQ65381.1|2630702_2631203_-|ferritin
MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFIQQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFYNLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGARTFDEE
>CP029649.1|AWQ66027.1|2629758_2630313_-|exonuclease-family-protein
MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNPQDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQNIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITFRLLKNYENLTYVTNIYGKNLKDKG
>CP029649.1|AWQ66526.1|2628621_2629692_+|impB/mucB/samB-family-protein
MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVYSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEKTHLTASAGVSYNKFLAKLASGMNKPDGMTVIDYQNVHDILMTLDIGEFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTYKNMTIYDFI
>CP029649.1|AWQ66882.1|2627844_2628375_+|hypothetical-protein
MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQNIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKWQFSIIMLSPLILLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYVQQDEDSIYLYHQKPTQ
>CP029649.1|AWQ66205.1|2626313_2627675_+|23S-rRNA-(uracil-5-)-methyltransferase-RumA
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSSIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>CP029649.1|AWQ67428.1|2625285_2626233_+|diacylglycerol-kinase
MRKRARIIYNPTSGKEQFKRELPDALIKLEKAGYETSAYATEKIGDATLEAERAMHENYDILIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRALHIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPFAYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGYFTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGGKLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE
>CP029649.1|AWQ65288.1|2636123_2636882_+|methionine-aminopeptidase,-type-I
MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAKELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYYADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLKVIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNEWAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE
>CP029649.1|AWQ66004.1|2637098_2637485_+|hypothetical-protein
MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITKKEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIETQIQQTSTEKIATEKTSYLINYMNAVA
>CP029649.1|AWQ66930.1|2637499_2638201_+|hypothetical-protein
MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLVYVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKVVATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTIVVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVNIYVSTFIGDVEVIYR
>CP029649.1|AWQ65800.1|2638197_2639241_+|sensor-protein-VraS
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVSQQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIEVKAPLNKEDSYDD
>CP029649.1|AWQ65719.1|2639230_2639860_+|response-regulator
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMDDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIAKGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ
>CP029649.1|AWQ66714.1|2639971_2641189_-|yihY-family-inner-membrane-domain-protein
MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQFQSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMFPMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILAIWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVISHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIVFIVLYSVAPNVKTKLKSVLPGAVFTSIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQRSVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDKNIKDKIVDKLKKD
>CP029649.1|AWQ66672.1|2641466_2641742_-|hypothetical-protein
MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTRKPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR
>CP029649.1|AWQ67443.1|2641748_2642213_-|low-molecular-weight-protein-tyrosine-phosphatase-PtpA
MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSWNLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKGQLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG
>CP029649.1|AWQ66179.1|2642359_2642560_+|hypothetical-protein
MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQSRERLSPSEVTAIADALGQLRHD
>CP029649.1|AWQ65726.1|2642571_2643819_+|thermophilic-metalloprotease-family-protein
MTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTHLIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHELKSYDVEARMDYVKRGAANLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKRVYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYVSEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPLSYNGTIIDQFKLMFKDGEIIDFSAEKGEAVLKDLINTDEGSRRLGEVALVPDDSPISNRNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSSDLTIYGIFEDGSKELVFENGNWASTF

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP029649_1	1.1\|649807\|26\|CP029649\|CRISPRCasFinder	649807-649832	26	CP029649.1	439864-439889	0	1.0
CP029649_1	1.1\|649807\|26\|CP029649\|CRISPRCasFinder	649807-649832	26	CP029649.1	918701-918726	1	0.962
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	1423712-1423743	1	0.969
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	1423767-1423798	1	0.969
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	2786065-2786096	1	0.969
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	127554-127578	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	351383-351407	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	351441-351465	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	440029-440053	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	750232-750256	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	960819-960843	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	960877-960901	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	960935-960959	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	960993-961017	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	1132943-1132967	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	1423731-1423755	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	1423786-1423810	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	1627916-1627940	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	1950071-1950095	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	2288191-2288215	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	2634483-2634507	1	0.96
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	2786084-2786108	1	0.96
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	CP029649.1	127621-127651	1	0.968
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	CP029649.1	439956-439986	1	0.968
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	CP029649.1	649841-649871	1	0.968
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	CP029649.1	1132870-1132900	1	0.968
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	CP029649.1	1423885-1423915	1	0.968
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	CP029649.1	2000572-2000602	1	0.968
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	CP029649.1	2288141-2288171	1	0.968
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	CP029649.1	127621-127651	1	0.968
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	CP029649.1	439956-439986	1	0.968
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	CP029649.1	649841-649871	1	0.968
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	CP029649.1	1132870-1132900	1	0.968
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	CP029649.1	1423885-1423915	1	0.968
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	CP029649.1	2000572-2000602	1	0.968
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	CP029649.1	2288141-2288171	1	0.968
CP029649_1	1.1\|649807\|26\|CP029649\|CRISPRCasFinder	649807-649832	26	CP029649.1	869972-869997	2	0.923
CP029649_1	1.1\|649807\|26\|CP029649\|CRISPRCasFinder	649807-649832	26	CP029649.1	1836462-1836487	2	0.923
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	960831-960862	2	0.938
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	960889-960920	2	0.938
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	960947-960978	2	0.938
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	1132924-1132955	2	0.938
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	1627897-1627928	2	0.938
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	1950052-1950083	2	0.938
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	2277283-2277314	2	0.938
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	CP029649.1	2625146-2625177	2	0.938
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	435539-435563	2	0.92
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	953678-953702	2	0.92
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	CP029649.1	2277271-2277295	2	0.92
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	CP029649.1	918605-918635	2	0.935
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	CP029649.1	961060-961090	2	0.935
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	CP029649.1	2277224-2277254	2	0.935
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	CP029649.1	918605-918635	2	0.935
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	CP029649.1	961060-961090	2	0.935
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	CP029649.1	2277224-2277254	2	0.935

1. spacer 1.1|649807|26|CP029649|CRISPRCasFinder matches to position: 439864-439889, mismatch: 0, identity: 1.0

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctatgttggggccccg	Protospacer
**************************

2. spacer 1.1|649807|26|CP029649|CRISPRCasFinder matches to position: 918701-918726, mismatch: 1, identity: 0.962

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttctgtgttggggccccg	Protospacer
************.*************

3. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 1423712-1423743, mismatch: 1, identity: 0.969

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaagcaatgcaagt	Protospacer
*********************.**********

4. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 1423767-1423798, mismatch: 1, identity: 0.969

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaagcaatgcaagt	Protospacer
*********************.**********

5. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 2786065-2786096, mismatch: 1, identity: 0.969

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacagacaatgcaagt	Protospacer
********************.***********

6. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 127554-127578, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

7. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 351383-351407, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

8. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 351441-351465, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

9. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 440029-440053, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

10. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 750232-750256, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

11. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 960819-960843, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

12. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 960877-960901, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

13. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 960935-960959, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

14. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 960993-961017, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

15. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 1132943-1132967, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

16. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 1423731-1423755, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacatagagaatttcgaaaagaaa	Protospacer
***** *******************

17. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 1423786-1423810, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacatagagaatttcgaaaagaaa	Protospacer
***** *******************

18. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 1627916-1627940, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

19. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 1950071-1950095, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

20. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 2288191-2288215, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

21. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 2634483-2634507, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

22. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 2786084-2786108, mismatch: 1, identity: 0.96

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaaagaaa	Protospacer
***** *******************

23. spacer 11.2|2635901|31|CP029649|PILER-CR matches to position: 127621-127651, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

24. spacer 11.2|2635901|31|CP029649|PILER-CR matches to position: 439956-439986, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

25. spacer 11.2|2635901|31|CP029649|PILER-CR matches to position: 649841-649871, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

26. spacer 11.2|2635901|31|CP029649|PILER-CR matches to position: 1132870-1132900, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

27. spacer 11.2|2635901|31|CP029649|PILER-CR matches to position: 1423885-1423915, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

28. spacer 11.2|2635901|31|CP029649|PILER-CR matches to position: 2000572-2000602, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

29. spacer 11.2|2635901|31|CP029649|PILER-CR matches to position: 2288141-2288171, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

30. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to position: 127621-127651, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

31. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to position: 439956-439986, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

32. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to position: 649841-649871, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

33. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to position: 1132870-1132900, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

34. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to position: 1423885-1423915, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

35. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to position: 2000572-2000602, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

36. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to position: 2288141-2288171, mismatch: 1, identity: 0.968

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcttacaataatgtg	Protospacer
**********************.********

37. spacer 1.1|649807|26|CP029649|CRISPRCasFinder matches to position: 869972-869997, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcctctgtgttggggccccg	Protospacer
********.***.*************

38. spacer 1.1|649807|26|CP029649|CRISPRCasFinder matches to position: 1836462-1836487, mismatch: 2, identity: 0.923

ccgccagcttctatgttggggccccg	CRISPR spacer
ccgccagcttttatgttgggcccccg	Protospacer
**********.********* *****

39. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 960831-960862, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaggcaatgcaagt	Protospacer
********************..**********

40. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 960889-960920, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaggcaatgcaagt	Protospacer
********************..**********

41. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 960947-960978, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaggcaatgcaagt	Protospacer
********************..**********

42. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 1132924-1132955, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaggcaatgcaagt	Protospacer
********************..**********

43. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 1627897-1627928, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaggcaatgcaagt	Protospacer
********************..**********

44. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 1950052-1950083, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaagaaattctacaggcaatgcaagt	Protospacer
********************..**********

45. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 2277283-2277314, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcaaaaagaaattctacagacaatgcaagt	Protospacer
****.***************.***********

46. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to position: 2625146-2625177, mismatch: 2, identity: 0.938

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
tttcgaaaggaaattctacagacaatgcaagt	Protospacer
********.***********.***********

47. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 435539-435563, mismatch: 2, identity: 0.92

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgataagaaa	Protospacer
***** ************ ******

48. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 953678-953702, mismatch: 2, identity: 0.92

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacacagagaatttcgaaatgaaa	Protospacer
***** ************** ****

49. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to position: 2277271-2277295, mismatch: 2, identity: 0.92

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacatagagaatttcaaaaagaaa	Protospacer
***** **********.********

50. spacer 11.2|2635901|31|CP029649|PILER-CR matches to position: 918605-918635, mismatch: 2, identity: 0.935

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacggaaagtcagcttacaataatgtg	Protospacer
********.*************.********

51. spacer 11.2|2635901|31|CP029649|PILER-CR matches to position: 961060-961090, mismatch: 2, identity: 0.935

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agcttacgaaaagtcagcttacaataatgtg	Protospacer
**** *****************.********

52. spacer 11.2|2635901|31|CP029649|PILER-CR matches to position: 2277224-2277254, mismatch: 2, identity: 0.935

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcatacaataatgtg	Protospacer
****************** ***.********

53. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to position: 918605-918635, mismatch: 2, identity: 0.935

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacggaaagtcagcttacaataatgtg	Protospacer
********.*************.********

54. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to position: 961060-961090, mismatch: 2, identity: 0.935

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agcttacgaaaagtcagcttacaataatgtg	Protospacer
**** *****************.********

55. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to position: 2277224-2277254, mismatch: 2, identity: 0.935

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
agctgacgaaaagtcagcatacaataatgtg	Protospacer
****************** ***.********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP029649_6	6.1\|1524243\|25\|CP029649\|CRISPRCasFinder	1524243-1524267	25	LC371242	Escherichia phage EcS1 DNA, complete sequence	15447-15471	2	0.92
CP029649_8	8.2\|1734280\|33\|CP029649\|CRISPRCasFinder,CRT	1734280-1734312	33	NC_013373	Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence	26794-26826	2	0.939
CP029649_8	8.3\|1734349\|35\|CP029649\|CRISPRCasFinder,CRT	1734349-1734383	35	MT926124	Staphylococcus phage vB_SauP_EBHT, complete genome	2846-2880	2	0.943
CP029649_8	8.3\|1734349\|35\|CP029649\|CRISPRCasFinder,CRT	1734349-1734383	35	MK922548	Staphylococcus phage SA46-CTH4, complete genome	3204-3238	2	0.943
CP029649_8	8.3\|1734349\|35\|CP029649\|CRISPRCasFinder,CRT	1734349-1734383	35	MK922547	Staphylococcus phage SA30-CTH2, complete genome	3197-3231	2	0.943
CP029649_8	8.3\|1734349\|35\|CP029649\|CRISPRCasFinder,CRT	1734349-1734383	35	KJ210330	Staphylococcus phage GRCS, complete genome	3491-3525	2	0.943
CP029649_8	8.3\|1734349\|35\|CP029649\|CRISPRCasFinder,CRT	1734349-1734383	35	MK936475	Staphylococcus phage SA03-CTH2, complete genome	14280-14314	2	0.943
CP029649_8	8.13\|1734280\|34\|CP029649\|PILER-CR	1734280-1734313	34	NC_013373	Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence	26794-26827	2	0.941
CP029649_7	7.7\|1725306\|36\|CP029649\|PILER-CR	1725306-1725341	36	MF417907	Uncultured Caudovirales phage clone 7F_7, partial genome	31447-31482	3	0.917
CP029649_7	7.7\|1725306\|36\|CP029649\|PILER-CR	1725306-1725341	36	KY653129	Staphylococcus phage IME1365_01, complete genome	11951-11986	3	0.917
CP029649_8	8.14\|1734349\|36\|CP029649\|PILER-CR	1734349-1734384	36	MK936475	Staphylococcus phage SA03-CTH2, complete genome	14279-14314	3	0.917
CP029649_8	8.14\|1734349\|36\|CP029649\|PILER-CR	1734349-1734384	36	MT926124	Staphylococcus phage vB_SauP_EBHT, complete genome	2846-2881	3	0.917
CP029649_8	8.14\|1734349\|36\|CP029649\|PILER-CR	1734349-1734384	36	MK922548	Staphylococcus phage SA46-CTH4, complete genome	3204-3239	3	0.917
CP029649_8	8.14\|1734349\|36\|CP029649\|PILER-CR	1734349-1734384	36	MK922547	Staphylococcus phage SA30-CTH2, complete genome	3197-3232	3	0.917
CP029649_8	8.14\|1734349\|36\|CP029649\|PILER-CR	1734349-1734384	36	KJ210330	Staphylococcus phage GRCS, complete genome	3491-3526	3	0.917
CP029649_7	7.2\|1725305\|37\|CP029649\|CRT	1725305-1725341	37	MF417907	Uncultured Caudovirales phage clone 7F_7, partial genome	31446-31482	4	0.892
CP029649_7	7.2\|1725305\|37\|CP029649\|CRT	1725305-1725341	37	KY653129	Staphylococcus phage IME1365_01, complete genome	11951-11987	4	0.892
CP029649_7	7.5\|1725305\|41\|CP029649\|CRISPRCasFinder	1725305-1725345	41	MF417907	Uncultured Caudovirales phage clone 7F_7, partial genome	31442-31482	6	0.854
CP029649_7	7.5\|1725305\|41\|CP029649\|CRISPRCasFinder	1725305-1725345	41	KY653129	Staphylococcus phage IME1365_01, complete genome	11951-11991	6	0.854
CP029649_8	8.1\|1734209\|35\|CP029649\|CRISPRCasFinder,CRT	1734209-1734243	35	NZ_CP043848	Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence	50879-50913	6	0.829
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	MN694790	Marine virus AFVG_250M551, complete genome	33981-34014	8	0.765
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	NZ_LR214999	Mycoplasma conjunctivae strain NCTC10147 plasmid 3	55978-56011	8	0.765
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	LR214965	Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11	45570-45603	8	0.765
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	NC_021536	Synechococcus phage S-IOM18 genomic sequence	159749-159779	8	0.742
CP029649_11	11.2\|2635901\|31\|CP029649\|PILER-CR	2635901-2635931	31	LN846932	Carnobacterium maltaromaticum strain LMA28 LMA_pa plamid, complete genome	10622-10652	8	0.742
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	NC_021536	Synechococcus phage S-IOM18 genomic sequence	159749-159779	8	0.742
CP029649_11	11.3\|2635890\|31\|CP029649\|CRISPRCasFinder	2635890-2635920	31	LN846932	Carnobacterium maltaromaticum strain LMA28 LMA_pa plamid, complete genome	10622-10652	8	0.742
CP029649_4	4.1\|966498\|32\|CP029649\|CRISPRCasFinder	966498-966529	32	MN693281	Marine virus AFVG_25M371, complete genome	6448-6479	9	0.719
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	123527-123560	9	0.735
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	NZ_CP028886	Borrelia turcica IST7 plasmid lp32-A, complete sequence	1427-1460	11	0.676
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1264667-1264700	12	0.647
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1264689-1264722	12	0.647
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1264689-1264722	12	0.647
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1264689-1264722	12	0.647
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1264689-1264722	12	0.647
CP029649_8	8.9\|1734780\|34\|CP029649\|CRISPRCasFinder,CRT	1734780-1734813	34	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1264689-1264722	12	0.647

1. spacer 6.1|1524243|25|CP029649|CRISPRCasFinder matches to LC371242 (Escherichia phage EcS1 DNA, complete sequence) position: , mismatch: 2, identity: 0.92

caacaaagagaatttcgaaaagaaa	CRISPR spacer
caacaaaaagaatttcgtaaagaaa	Protospacer
*******.********* *******

2. spacer 8.2|1734280|33|CP029649|CRISPRCasFinder,CRT matches to NC_013373 (Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence) position: , mismatch: 2, identity: 0.939

tacaaatgaattaatcagtgacatgaaagatga	CRISPR spacer
tacaaatgaattaatcaatgatatgaaagatga	Protospacer
*****************.***.***********

3. spacer 8.3|1734349|35|CP029649|CRISPRCasFinder,CRT matches to MT926124 (Staphylococcus phage vB_SauP_EBHT, complete genome) position: , mismatch: 2, identity: 0.943

cctaaaatatttttattaggtaatgccgttaactt	CRISPR spacer
ccaaaaatatttttattaggtaatgctgttaactt	Protospacer
** ***********************.********

4. spacer 8.3|1734349|35|CP029649|CRISPRCasFinder,CRT matches to MK922548 (Staphylococcus phage SA46-CTH4, complete genome) position: , mismatch: 2, identity: 0.943

cctaaaatatttttattaggtaatgccgttaactt	CRISPR spacer
cctaaaatattcttattaggtaatgctgttaactt	Protospacer
***********.**************.********

5. spacer 8.3|1734349|35|CP029649|CRISPRCasFinder,CRT matches to MK922547 (Staphylococcus phage SA30-CTH2, complete genome) position: , mismatch: 2, identity: 0.943

cctaaaatatttttattaggtaatgccgttaactt	CRISPR spacer
cctaaaatattcttattaggtaatgctgttaactt	Protospacer
***********.**************.********

6. spacer 8.3|1734349|35|CP029649|CRISPRCasFinder,CRT matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 2, identity: 0.943

cctaaaatatttttattaggtaatgccgttaactt	CRISPR spacer
ccaaaaatatttttattaggtaatgctgttaactt	Protospacer
** ***********************.********

7. spacer 8.3|1734349|35|CP029649|CRISPRCasFinder,CRT matches to MK936475 (Staphylococcus phage SA03-CTH2, complete genome) position: , mismatch: 2, identity: 0.943

cctaaaatatttttattaggtaatgccgttaactt	CRISPR spacer
cctaaaatattcttattaggtaatgctgttaactt	Protospacer
***********.**************.********

8. spacer 8.13|1734280|34|CP029649|PILER-CR matches to NC_013373 (Staphylococcus sp. CDC3 plasmid SAP020A, complete sequence) position: , mismatch: 2, identity: 0.941

tacaaatgaattaatcagtgacatgaaagatgag	CRISPR spacer
tacaaatgaattaatcaatgatatgaaagatgag	Protospacer
*****************.***.************

9. spacer 7.7|1725306|36|CP029649|PILER-CR matches to MF417907 (Uncultured Caudovirales phage clone 7F_7, partial genome) position: , mismatch: 3, identity: 0.917

agtggtccagaattaatacatggtaaaggagtatat	CRISPR spacer
cgtggtccagaattaatacatggcaagggagtatat	Protospacer
 **********************.**.*********

10. spacer 7.7|1725306|36|CP029649|PILER-CR matches to KY653129 (Staphylococcus phage IME1365_01, complete genome) position: , mismatch: 3, identity: 0.917

agtggtccagaattaatacatggtaaaggagtatat	CRISPR spacer
cgtggtccagaattaatacatggcaaaggagtttat	Protospacer
 **********************.******** ***

11. spacer 8.14|1734349|36|CP029649|PILER-CR matches to MK936475 (Staphylococcus phage SA03-CTH2, complete genome) position: , mismatch: 3, identity: 0.917

cctaaaatatttttattaggtaatgccgttaactta	CRISPR spacer
cctaaaatattcttattaggtaatgctgttaacttt	Protospacer
***********.**************.********

12. spacer 8.14|1734349|36|CP029649|PILER-CR matches to MT926124 (Staphylococcus phage vB_SauP_EBHT, complete genome) position: , mismatch: 3, identity: 0.917

cctaaaatatttttattaggtaatgccgttaactta	CRISPR spacer
ccaaaaatatttttattaggtaatgctgttaacttt	Protospacer
** ***********************.********

13. spacer 8.14|1734349|36|CP029649|PILER-CR matches to MK922548 (Staphylococcus phage SA46-CTH4, complete genome) position: , mismatch: 3, identity: 0.917

cctaaaatatttttattaggtaatgccgttaactta	CRISPR spacer
cctaaaatattcttattaggtaatgctgttaacttt	Protospacer
***********.**************.********

14. spacer 8.14|1734349|36|CP029649|PILER-CR matches to MK922547 (Staphylococcus phage SA30-CTH2, complete genome) position: , mismatch: 3, identity: 0.917

cctaaaatatttttattaggtaatgccgttaactta	CRISPR spacer
cctaaaatattcttattaggtaatgctgttaacttt	Protospacer
***********.**************.********

15. spacer 8.14|1734349|36|CP029649|PILER-CR matches to KJ210330 (Staphylococcus phage GRCS, complete genome) position: , mismatch: 3, identity: 0.917

cctaaaatatttttattaggtaatgccgttaactta	CRISPR spacer
ccaaaaatatttttattaggtaatgctgttaacttt	Protospacer
** ***********************.********

16. spacer 7.2|1725305|37|CP029649|CRT matches to MF417907 (Uncultured Caudovirales phage clone 7F_7, partial genome) position: , mismatch: 4, identity: 0.892

agtggtccagaattaatacatggtaaaggagtatatc	CRISPR spacer
cgtggtccagaattaatacatggcaagggagtatatg	Protospacer
 **********************.**.*********

17. spacer 7.2|1725305|37|CP029649|CRT matches to KY653129 (Staphylococcus phage IME1365_01, complete genome) position: , mismatch: 4, identity: 0.892

agtggtccagaattaatacatggtaaaggagtatatc	CRISPR spacer
cgtggtccagaattaatacatggcaaaggagtttatg	Protospacer
 **********************.******** ***

18. spacer 7.5|1725305|41|CP029649|CRISPRCasFinder matches to MF417907 (Uncultured Caudovirales phage clone 7F_7, partial genome) position: , mismatch: 6, identity: 0.854

agtggtccagaattaatacatggtaaaggagtatatcagtt	CRISPR spacer
cgtggtccagaattaatacatggcaagggagtatatgaata	Protospacer
 **********************.**.********* *.*

19. spacer 7.5|1725305|41|CP029649|CRISPRCasFinder matches to KY653129 (Staphylococcus phage IME1365_01, complete genome) position: , mismatch: 6, identity: 0.854

agtggtccagaattaatacatggtaaaggagtatatcagtt	CRISPR spacer
cgtggtccagaattaatacatggcaaaggagtttatgaata	Protospacer
 **********************.******** *** *.*

20. spacer 8.1|1734209|35|CP029649|CRISPRCasFinder,CRT matches to NZ_CP043848 (Staphylococcus epidermidis strain NCCP 16828 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.829

accgacgttttattacctattgagcaactattacc	CRISPR spacer
gtaaacgttttattacctatcgagcaactattccc	Protospacer
.. .****************.*********** **

21. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to MN694790 (Marine virus AFVG_250M551, complete genome) position: , mismatch: 8, identity: 0.765

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
ctagagtgtaatgaaattatagaaatagaaaatt	Protospacer
 * *..  ******* ******** *********

22. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to NZ_LR214999 (Mycoplasma conjunctivae strain NCTC10147 plasmid 3) position: , mismatch: 8, identity: 0.765

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
accagaaacaatgaacttatagaattagctaaac	Protospacer
*.*.*** .*******************  ** .

23. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to LR214965 (Mycoplasma fermentans strain NCTC10117 genome assembly, plasmid: 11) position: , mismatch: 8, identity: 0.765

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
accagaaacaatgaacttatagaattagctaaac	Protospacer
*.*.*** .*******************  ** .

24. spacer 11.2|2635901|31|CP029649|PILER-CR matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 8, identity: 0.742

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
gcttgacgaaaactcaccttacgataaaatt	Protospacer
. .********* *** ********** .*

25. spacer 11.2|2635901|31|CP029649|PILER-CR matches to LN846932 (Carnobacterium maltaromaticum strain LMA28 LMA_pa plamid, complete genome) position: , mismatch: 8, identity: 0.742

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
tgaagacgaaaaatcagattacgataaatta	Protospacer
 *  ********.**** *********  *.

26. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to NC_021536 (Synechococcus phage S-IOM18 genomic sequence) position: , mismatch: 8, identity: 0.742

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
gcttgacgaaaactcaccttacgataaaatt	Protospacer
. .********* *** ********** .*

27. spacer 11.3|2635890|31|CP029649|CRISPRCasFinder matches to LN846932 (Carnobacterium maltaromaticum strain LMA28 LMA_pa plamid, complete genome) position: , mismatch: 8, identity: 0.742

agctgacgaaaagtcagcttacgataatgtg	CRISPR spacer
tgaagacgaaaaatcagattacgataaatta	Protospacer
 *  ********.**** *********  *.

28. spacer 4.1|966498|32|CP029649|CRISPRCasFinder matches to MN693281 (Marine virus AFVG_25M371, complete genome) position: , mismatch: 9, identity: 0.719

tttcgaaaagaaattctacaaacaatgcaagt	CRISPR spacer
cacttagaagaaatcctacaaacaatgcaaaa	Protospacer
. .. *.*******.***************.

29. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 9, identity: 0.735

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
aatagaataaatgaacttgtagaattagtcaaag	Protospacer
* ..**** *********.*********  **

30. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to NZ_CP028886 (Borrelia turcica IST7 plasmid lp32-A, complete sequence) position: , mismatch: 11, identity: 0.676

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
gaaaagaataataaacttaaagaattagaaaaga	Protospacer
.  ...* ****.****** ************

31. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
tccggagttaatgaacttatagtattccgtctca	Protospacer
 .****.*************** ***  .   .

32. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
tccggagttaatgaacttatagtattccgtctca	Protospacer
 .****.*************** ***  .   .

33. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
tccggagttaatgaacttatagtattccgtctca	Protospacer
 .****.*************** ***  .   .

34. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
tccggagttaatgaacttatagtattccgtctca	Protospacer
 .****.*************** ***  .   .

35. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
tccggagttaatgaacttatagtattccgtctca	Protospacer
 .****.*************** ***  .   .

36. spacer 8.9|1734780|34|CP029649|CRISPRCasFinder,CRT matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 12, identity: 0.647

atcggaattaatgaacttatagaattagaaaatt	CRISPR spacer
tccggagttaatgaacttatagtattccgtctca	Protospacer
 .****.*************** ***  .   .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

70956 : 79996

uncultured_Mediterranean_phage(50.0%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ66128.1\|70956_71961_+	holliday junction DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1
AWQ66444.1\|71962_72988_+\|tRNA	tRNA ribosyltransferase-isomerase	NA	NA	NA	NA
AWQ67578.1\|73010_74150_+\|tRNA	queuine tRNA-ribosyltransferase	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.6e-84	44.7
AWQ65677.1\|74168_74429_+	preprotein translocase, YajC subunit	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
AWQ66162.1\|74703_76983_+	protein-export membrane protein SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
AWQ67665.1\|77185_79456_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	2.4e-63	29.3
AWQ67469.1\|79477_79996_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5

DBSCAN-SWA_2

211992 : 297373

100

Staphylococcus_phage(84.0%)

integrase,head,capsid,protease,portal,tail,holin,tRNA,terminase

attL 212696:212713|attR 258761:258778

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ67048.1\|211992_213687_+	sensor protein SrrB	A0A1V0SGX0	Hokovirus	1.7e-21	33.6
212696:212713	attL	NA	NA	NA	NA
AWQ66797.1\|213991_214840_+	hypothetical protein	NA	NA	NA	NA
AWQ66028.1\|214991_216878_+	hypothetical protein	B5WZK7	Staphylococcus_phage	2.3e-112	95.8
AWQ65946.1\|216920_218126_-\|integrase	phage integrase family protein	A0A2I6PEN0	Staphylococcus_phage	2.2e-222	99.8
AWQ65577.1\|218251_218866_+	hypothetical protein	A0A2I6PEZ0	Staphylococcus_phage	6.7e-106	100.0
AWQ66584.1\|218862_218988_-	hypothetical protein	A0A2I6PEK8	Staphylococcus_phage	3.3e-12	100.0
AWQ67716.1\|219044_219227_-	hypothetical protein	A0A2I6PDR4	Staphylococcus_phage	5.3e-27	100.0
AWQ66453.1\|219296_220028_-	helix-turn-helix domain protein	S4SVC5	Staphylococcus_phage	1.3e-132	99.2
AWQ66038.1\|220179_220392_+	helix-turn-helix family protein	A7TWF1	Staphylococcus_phage	1.6e-30	100.0
AWQ66462.1\|220439_220883_+	hypothetical protein	A7TWF2	Staphylococcus_phage	8.9e-76	100.0
AWQ65162.1\|220897_221047_+	hypothetical protein	D2JGJ0	Staphylococcus_phage	1.4e-20	100.0
AWQ65324.1\|221087_221300_-	putative uracil-DNA glycosylase	D2JGJ1	Staphylococcus_phage	2.2e-32	98.6
AWQ67408.1\|221369_221567_+	hypothetical protein	A7TWF5	Staphylococcus_phage	4.6e-24	100.0
AWQ66160.1\|222214_222580_-	putative phage protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
AWQ65241.1\|222634_222850_+	hypothetical protein	A0A2I6PF01	Staphylococcus_phage	1.9e-31	100.0
AWQ65450.1\|222874_223138_+	homeo-like domain protein	A7TWG0	Staphylococcus_phage	5.7e-46	100.0
AWQ66733.1\|223390_223714_+	hypothetical protein	A0A2I6PE70	Staphylococcus_phage	6.5e-52	100.0
AWQ67700.1\|223728_224091_+	hypothetical protein	B5WZM2	Staphylococcus_phage	8.3e-56	100.0
AWQ65439.1\|224087_225254_+	hypothetical protein	A0A2I6PEL9	Staphylococcus_phage	7.7e-220	99.0
AWQ65811.1\|225280_225838_+	hypothetical protein	A0A2I6PF05	Staphylococcus_phage	1.8e-97	100.0
AWQ66798.1\|225897_227859_+	DNA polymerase A family protein	A0A2K9VBT3	Staphylococcus_phage	0.0e+00	98.9
AWQ65529.1\|227871_228057_+	hypothetical protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
AWQ66863.1\|228056_228248_+	PVL ORF-50-like family protein	A0A2I6PEL5	Staphylococcus_phage	3.3e-27	100.0
AWQ67381.1\|228317_228458_+	PVL ORF-50-like family protein	A0A2I6PEL5	Staphylococcus_phage	5.7e-21	97.8
AWQ67643.1\|228457_228715_+	hypothetical protein	A0A2I6PEN5	Staphylococcus_phage	7.5e-43	98.8
AWQ66441.1\|228717_228918_+	hypothetical protein	A0A2I6PEM3	Staphylococcus_phage	2.5e-30	100.0
AWQ67094.1\|228932_229175_+	phage family protein	A0A2I6PEV3	Staphylococcus_phage	1.5e-40	100.0
AWQ66744.1\|229189_229444_+	hypothetical protein	B5WZN0	Staphylococcus_phage	5.0e-39	98.8
AWQ66669.1\|229430_229601_+	hypothetical protein	A0A1W6JQ22	Staphylococcus_phage	5.7e-23	100.0
AWQ66197.1\|229593_230130_+	dUTPase family protein	M1SNY5	Staphylococcus_phage	5.5e-96	100.0
AWQ66325.1\|230166_230340_+	hypothetical protein	A0A1W6JQ45	Staphylococcus_phage	4.7e-25	100.0
AWQ65485.1\|230356_230593_+	hypothetical protein	M1T303	Staphylococcus_phage	9.6e-37	100.0
AWQ67396.1\|230617_230854_+	hypothetical protein	A7TWB3	Staphylococcus_phage	1.9e-37	100.0
AWQ65861.1\|230846_231233_+	hypothetical protein	A0A1X9IGZ2	Staphylococcus_phage	3.0e-64	100.0
AWQ67012.1\|231229_231382_+	transcriptional activator RinB family protein	A7TWI2	Staphylococcus_phage	1.3e-18	98.0
AWQ67526.1\|231449_231650_+	hypothetical protein	A0A2I6PF41	Staphylococcus_phage	2.9e-26	100.0
AWQ67130.1\|231702_234150_+	virulence-associated E family protein	A0A2I6PEP4	Staphylococcus_phage	0.0e+00	99.9
AWQ65645.1\|234490_234781_+	VRR-NUC domain protein	U5U7A3	Staphylococcus_phage	4.9e-51	100.0
AWQ65492.1\|234770_236129_+	DEAD/DEAH box helicase family protein	A0A2K9VBW3	Staphylococcus_phage	4.3e-262	100.0
AWQ65434.1\|236141_236579_+	phage transcriptional regulator, RinA family protein	A0A2K9VBV2	Staphylococcus_phage	6.1e-77	100.0
AWQ66682.1\|236735_237056_+	HNH endonuclease family protein	A0A2K9VBV6	Staphylococcus_phage	1.1e-56	99.1
AWQ67313.1\|237180_237486_+\|terminase	phage terminase, small subunit	U5U414	Staphylococcus_phage	2.9e-49	100.0
AWQ67227.1\|237475_239167_+	phage Terminase family protein	A0A2K9VBQ1	Staphylococcus_phage	0.0e+00	100.0
AWQ67257.1\|239171_240410_+\|portal	phage portal protein, HK97 family	A0A2K9VBP0	Staphylococcus_phage	2.0e-234	99.5
AWQ65648.1\|240393_241167_+\|protease	clp protease family protein	M1TAZ4	Staphylococcus_phage	9.2e-137	100.0
AWQ65984.1\|241178_242342_+\|capsid	phage major capsid protein, HK97 family	A0A2I6PDD7	Staphylococcus_phage	9.4e-218	100.0
AWQ65170.1\|242410_242689_+\|head,tail	phage gp6-like head-tail connector family protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
AWQ67208.1\|242700_243033_+	hypothetical protein	A0A2I6PDD6	Staphylococcus_phage	6.2e-58	100.0
AWQ66376.1\|243029_243431_+	hypothetical protein	A0A2I6PDD3	Staphylococcus_phage	6.2e-68	100.0
AWQ66105.1\|243431_243827_+	hypothetical protein	A0A2I6PDD8	Staphylococcus_phage	2.6e-66	100.0
AWQ65851.1\|243861_244503_+\|tail	phage major tail, phi13 family protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
AWQ67545.1\|244594_245050_+	bacterial Ig-like domain family protein	A0A2I6PF45	Staphylococcus_phage	1.3e-77	100.0
AWQ66257.1\|245107_245458_+	hypothetical protein	A0A2I6PDE6	Staphylococcus_phage	1.1e-55	100.0
AWQ65977.1\|245499_245658_+	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
AWQ65163.1\|245671_251872_+\|tail	phage tail tape measure protein, TP901 family, core region	A0A2I6PF36	Staphylococcus_phage	0.0e+00	99.2
AWQ65871.1\|251871_252696_+\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	1.2e-158	99.6
AWQ66005.1\|252704_254288_+\|tail	prophage endopeptidase tail family protein	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
AWQ66854.1\|254287_254578_+	putative phage protein	U5U457	Staphylococcus_phage	2.7e-49	99.0
AWQ65448.1\|254593_256504_+	putative minor structural protein	A0A2I6PEQ9	Staphylococcus_phage	0.0e+00	100.0
AWQ66750.1\|256503_257970_+	hypothetical protein	A0A2I6PE72	Staphylococcus_phage	6.4e-272	99.4
AWQ67242.1\|257969_258359_+	hypothetical protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
AWQ65654.1\|258351_258516_+	hypothetical protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
AWQ66610.1\|258561_258861_+	hypothetical protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
258761:258778	attR	NA	NA	NA	NA
AWQ67751.1\|258996_259299_+\|holin	holin, SPP1 family	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
AWQ66180.1\|259309_260764_+	N-acetylmuramoyl-L-alanine amidase family protein	A0A2I6PF47	Staphylococcus_phage	2.8e-288	99.6
AWQ66916.1\|261515_261701_+	hypothetical protein	A0ZS61	Staphylococcus_virus	1.7e-25	100.0
AWQ65243.1\|261791_262697_+	hypothetical protein	NA	NA	NA	NA
AWQ65972.1\|262754_263672_+	hypothetical protein	NA	NA	NA	NA
AWQ67206.1\|263832_264411_+	hypothetical protein	NA	NA	NA	NA
AWQ65128.1\|264490_264643_+	hypothetical protein	NA	NA	NA	NA
AWQ65438.1\|265052_265598_+	riboflavin transporter RibU	NA	NA	NA	NA
AWQ66549.1\|265703_265952_-	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
AWQ66963.1\|266059_267013_+	hypothetical protein	NA	NA	NA	NA
AWQ67664.1\|267002_268382_+	ATP-dependent DNA helicase, RecQ family protein	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	4.9e-56	33.6
AWQ66622.1\|268534_269995_+	elastin-binding protein EbpS	NA	NA	NA	NA
AWQ67527.1\|270396_271383_+	glucose inhibited division A family protein	NA	NA	NA	NA
AWQ65814.1\|271497_272466_-	asparaginase family protein	NA	NA	NA	NA
AWQ67566.1\|272542_273202_+	cytidylate kinase	NA	NA	NA	NA
AWQ66998.1\|273232_273349_+	hypothetical protein	NA	NA	NA	NA
AWQ65514.1\|273913_275089_+	30S ribosomal protein S1	NA	NA	NA	NA
AWQ65540.1\|275310_276621_+	GTP-binding protein Era	NA	NA	NA	NA
AWQ66625.1\|276637_277636_+	NAD-dependent glycerol-3-phosphate dehydrogenase family protein	NA	NA	NA	NA
AWQ67405.1\|277806_278079_+	DNA-binding protein HU	A7KV42	Bacillus_phage	4.2e-28	73.3
AWQ66535.1\|278509_279082_+	heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 family protein	NA	NA	NA	NA
AWQ66485.1\|279084_279810_+	demethylmenaquinone methyltransferase	NA	NA	NA	NA
AWQ66693.1\|279811_280771_+	heptaprenyl diphosphate synthase component 2	A0A1V0SE37	Indivirus	7.5e-11	24.4
AWQ65605.1\|280862_281312_+	nucleoside diphosphate kinase	D2E8E1	Anguillid_herpesvirus	2.4e-28	43.8
AWQ67678.1\|282106_283273_+	chorismate synthase	A0A291AU41	Pandoravirus	5.8e-34	31.8
AWQ66562.1\|283298_284363_+	3-dehydroquinate synthase	NA	NA	NA	NA
AWQ67240.1\|284372_285671_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
AWQ67025.1\|285677_286922_+	TPR repeat family protein	NA	NA	NA	NA
AWQ65138.1\|286935_287511_+	hypothetical protein	G3MAV7	Bacillus_virus	2.1e-08	27.2
AWQ65905.1\|287500_288088_+	hypothetical protein	NA	NA	NA	NA
AWQ65894.1\|288141_288840_+	neutral zinc metallopeptidase family protein	NA	NA	NA	NA
AWQ65398.1\|289176_289494_+	mazG nucleotide pyrophosphohydrolase domain protein	NA	NA	NA	NA
AWQ66847.1\|289734_290877_+	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
AWQ67445.1\|290881_292084_+\|head	poly A polymerase head domain protein	H7BUW3	unidentified_phage	3.2e-35	42.5
AWQ67470.1\|292070_293042_+	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
AWQ67250.1\|293065_295759_+	hypothetical protein	A0A1X9I5C8	Streptococcus_phage	1.8e-46	34.7
AWQ66016.1\|296080_297373_+\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.9e-54	30.0

DBSCAN-SWA_3

740429 : 748902

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ67107.1\|740429_740996_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	3.6e-29	40.1
AWQ67060.1\|740998_742027_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	3.4e-62	41.7
AWQ66527.1\|742019_743504_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.2e-45	31.5
AWQ65647.1\|743482_745672_-	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	1.0e-140	39.7
AWQ65509.1\|745664_746336_-	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
AWQ65826.1\|746337_746601_-	phosphoribosylformylglycinamidine synthase, purS protein	NA	NA	NA	NA
AWQ66460.1\|746600_747305_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
AWQ67164.1\|747308_748433_-	N5-carboxyaminoimidazole ribonucleotide synthase	NA	NA	NA	NA
AWQ66226.1\|748419_748902_-	phosphoribosylaminoimidazole carboxylase, catalytic subunit	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7

DBSCAN-SWA_4

994904 : 1009258

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ65470.1\|994904_995666_-	ABC transporter family protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6
AWQ65249.1\|995662_996619_-	fecCD transport family protein	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
AWQ67334.1\|996605_997577_-	fecCD transport family protein	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
AWQ66635.1\|997951_998923_-	ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
AWQ66913.1\|999040_1001146_-	ribonucleoside-diphosphate reductase, alpha subunit	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
AWQ65714.1\|1001108_1001507_-	nrdI protein	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
AWQ65564.1\|1002320_1003187_+	eamA-like transporter family protein	NA	NA	NA	NA
AWQ67573.1\|1003206_1003707_+	7-cyano-7-deazaguanine reductase	E7DN65	Pneumococcus_phage	5.9e-52	71.5
AWQ65665.1\|1004047_1005553_+	H+ symporter family protein	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
AWQ66367.1\|1005821_1006739_+	putative lipid kinase	A0A1V0SBJ0	Catovirus	2.8e-07	22.4
AWQ65340.1\|1007362_1007905_-	putative 5'(3')-deoxyribonucleotidase	NA	NA	NA	NA
AWQ67065.1\|1008199_1009258_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7

DBSCAN-SWA_5

1021229 : 1029049

Pandoravirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ66023.1\|1021229_1022381_-	chorismate binding enzyme family protein	S4VNU7	Pandoravirus	7.8e-23	35.7
AWQ65274.1\|1022364_1022958_-	glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
AWQ67009.1\|1023308_1023977_+	queuosine biosynthesis protein QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
AWQ67438.1\|1023978_1024398_+	queuosine biosynthesis protein QueD	S4U060	uncultured_phage	6.3e-07	28.7
AWQ65859.1\|1024401_1025115_+	7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
AWQ66647.1\|1025213_1025798_+	putative membrane protein	NA	NA	NA	NA
AWQ66937.1\|1026077_1026518_+	electron transfer DM13 family protein	NA	NA	NA	NA
AWQ67073.1\|1026859_1027333_+	doxX family protein	NA	NA	NA	NA
AWQ65496.1\|1027307_1027994_+	response regulator	NA	NA	NA	NA
AWQ67721.1\|1027993_1029049_+	histidine protein kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8

DBSCAN-SWA_6

1363049 : 1379070

Staphylococcus_phage(75.0%)

integrase,coat,terminase

attL 1354077:1354093|attR 1376033:1376049

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1354077:1354093	attL	NA	NA	NA	NA
AWQ67279.1\|1363049_1363604_+	hypothetical protein	A0A1W6JQE5	Staphylococcus_phage	1.2e-58	66.7
AWQ65219.1\|1363814_1364954_-	FRG domain protein	NA	NA	NA	NA
AWQ67695.1\|1364940_1365543_-	hypothetical protein	NA	NA	NA	NA
AWQ66917.1\|1365711_1366281_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	7.1e-102	99.5
AWQ67415.1\|1366277_1366619_-	putative pathogenicity island protein	Q4ZE86	Staphylococcus_phage	7.6e-59	100.0
AWQ66396.1\|1366621_1367149_-\|coat	putative spore coat protein	Q4ZE87	Staphylococcus_phage	6.8e-91	100.0
AWQ66232.1\|1367201_1367855_-	hypothetical protein	Q4ZE82	Staphylococcus_phage	7.6e-116	99.5
AWQ66094.1\|1367885_1368227_-	putative saPI1 ORF8-like protein	Q4ZE66	Staphylococcus_phage	2.9e-58	100.0
AWQ65682.1\|1368762_1369404_-	putative saPI1 ORF9-like protein	Q4ZE67	Staphylococcus_phage	3.1e-114	96.2
AWQ66640.1\|1369400_1369781_-	putative interference protein with phage growth	Q4ZE71	Staphylococcus_phage	3.8e-67	96.8
AWQ65676.1\|1370111_1371821_-	hypothetical protein	Q4ZE73	Staphylococcus_phage	0.0e+00	95.4
AWQ67697.1\|1371834_1372704_-	primase C terminal 1 family protein	Q4ZE74	Staphylococcus_phage	1.0e-163	94.8
AWQ65573.1\|1372770_1373088_-	hypothetical protein	Q4ZE75	Staphylococcus_phage	1.2e-18	48.1
AWQ67283.1\|1373090_1373300_-	putative pathogenicity island protein	Q4ZE76	Staphylococcus_phage	5.9e-30	94.2
AWQ67278.1\|1373292_1373439_-	putative pathogenicity island protein	NA	NA	NA	NA
AWQ66594.1\|1373485_1373746_-	hypothetical protein	NA	NA	NA	NA
AWQ66950.1\|1373747_1373945_-	helix-turn-helix family protein	NA	NA	NA	NA
AWQ66498.1\|1374088_1374712_+	helix-turn-helix family protein	Q20DG0	Lactobacillus_phage	2.4e-10	42.3
AWQ67360.1\|1374807_1375944_+\|integrase	phage integrase family protein	A0A1S5S7K9	Streptococcus_phage	9.3e-77	42.5
AWQ67080.1\|1376037_1377579_-	GMP synthase	A0A1V0SH76	Hokovirus	1.2e-23	32.6
1376033:1376049	attR	NA	NA	NA	NA
AWQ66310.1\|1377603_1379070_-	inosine-5'-monophosphate dehydrogenase	A0A1V0SHK8	Klosneuvirus	5.2e-96	40.5

DBSCAN-SWA_7

2517170 : 2591840

Staphylococcus_phage(94.37%)

integrase,head,capsid,protease,portal,transposase,tail,holin

attL 2529137:2529154|attR 2598504:2598521

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ65548.1\|2517170_2517914_-\|protease	CAAX protease self-immunity family protein	NA	NA	NA	NA
AWQ66936.1\|2518090_2518375_+	10 kDa chaperonin	A0A221S386	uncultured_virus	4.7e-14	46.2
AWQ65494.1\|2518450_2520067_+	chaperonin GroL	A0A240F779	uncultured_virus	3.4e-157	54.7
AWQ65388.1\|2520600_2521908_-	ktr system potassium uptake protein B	NA	NA	NA	NA
AWQ66483.1\|2522068_2522980_+	periplasmic binding family protein	NA	NA	NA	NA
AWQ67696.1\|2523041_2523842_+	leucine carboxyl methyltransferase family protein	NA	NA	NA	NA
AWQ66781.1\|2524259_2525483_-	putative succinyl-diaminopimelate desuccinylase	NA	NA	NA	NA
AWQ67562.1\|2525918_2526971_+	hypothetical protein	A0A2I6PER8	Staphylococcus_phage	2.4e-34	31.8
AWQ65936.1\|2526992_2528009_+	gamma-hemolysin component B	A0A2I6PER8	Staphylococcus_phage	5.1e-26	29.3
AWQ67604.1\|2528246_2529071_-	sphingomyelin phosphodiesterase	A0A1P8L6H7	Staphylococcus_phage	6.8e-162	100.0
AWQ65300.1\|2529127_2530165_-\|integrase	integrase	A0A1X9H022	Staphylococcus_phage	2.6e-179	100.0
2529137:2529154	attL	NA	NA	NA	NA
AWQ66284.1\|2530337_2530877_-	pemK-like family protein	U5U4R0	Staphylococcus_phage	9.0e-14	33.1
AWQ65917.1\|2531016_2531184_-	hypothetical protein	A0A0H3U4Z4	Staphylococcus_phage	6.6e-24	100.0
AWQ65294.1\|2531734_2532667_-	exonuclease family protein	A0A2I6PEZ7	Staphylococcus_phage	5.7e-173	100.0
AWQ67743.1\|2532682_2533396_-	helix-turn-helix family protein	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
AWQ65222.1\|2533528_2533792_+	helix-turn-helix family protein	A0A2I6PF09	Staphylococcus_phage	7.2e-41	100.0
AWQ66771.1\|2533807_2534005_+	putative phi PVL orf 35-like protein	O80075	Staphylococcus_phage	3.5e-24	87.7
AWQ67183.1\|2533991_2534372_-	hypothetical protein	Q9T1Z5	Staphylococcus_phage	1.2e-68	100.0
AWQ67349.1\|2534426_2534750_+	hypothetical protein	A0A075LYF5	Staphylococcus_phage	3.0e-57	100.0
AWQ66700.1\|2535002_2535305_+	hypothetical protein	A0A1P8L6F8	Staphylococcus_phage	7.0e-48	100.0
AWQ67417.1\|2535309_2535570_+	hypothetical protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
AWQ65780.1\|2535850_2537794_+	AAA domain protein	S4V9K6	Staphylococcus_phage	0.0e+00	100.0
AWQ65657.1\|2537795_2538716_+	recombinase, phage RecT family protein	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
AWQ66855.1\|2538928_2539414_+	beta-lactamase superfamily domain protein	A0A0H3U2T4	Staphylococcus_phage	4.2e-87	100.0
AWQ66044.1\|2539414_2539885_+	single-stranded DNA-binding family protein	A0EWX3	Staphylococcus_phage	7.4e-81	99.4
AWQ66340.1\|2539914_2540808_+	dnaD domain protein	A0A2I6PDG7	Staphylococcus_phage	2.1e-140	99.0
AWQ65334.1\|2540814_2541033_+	hypothetical protein	A0A2I6PDG4	Staphylococcus_phage	1.0e-37	100.0
AWQ67447.1\|2541041_2541446_+	endodeoxyribonuclease RusA family protein	A0EWX6	Staphylococcus_phage	1.9e-72	100.0
AWQ66787.1\|2541458_2541827_+	PVL ORF-50-like family protein	A0A0H3U2T3	Staphylococcus_phage	2.0e-49	100.0
AWQ65280.1\|2541830_2542073_+	phage family protein	A0A2H4PQJ3	Staphylococcus_phage	6.6e-41	100.0
AWQ65445.1\|2542137_2542587_+	yopX family protein	A0A2I6PDH2	Staphylococcus_phage	2.1e-80	99.3
AWQ65788.1\|2542583_2543093_+	hypothetical protein	A0A1X9H0D4	Staphylococcus_phage	3.2e-93	100.0
AWQ65194.1\|2543089_2543500_+	acetyltransferase family protein	A0A1X9H0B8	Staphylococcus_phage	2.3e-70	100.0
AWQ66773.1\|2543564_2543981_+	hypothetical protein	NA	NA	NA	NA
AWQ66335.1\|2543973_2544510_+	dUTPase family protein	A0A0H3U2Z8	Staphylococcus_phage	2.7e-95	99.4
AWQ65729.1\|2544546_2544792_+	putative membrane protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
AWQ65167.1\|2544788_2544995_+	hypothetical protein	A0A0H3U2R7	Staphylococcus_phage	1.3e-29	100.0
AWQ65282.1\|2544991_2545378_+	hypothetical protein	W5R986	Staphylococcus_phage	3.0e-64	100.0
AWQ65643.1\|2545374_2545524_+	transcriptional activator RinB family protein	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
AWQ66239.1\|2545523_2545724_+	hypothetical protein	A0A2I6PDV9	Staphylococcus_phage	1.4e-28	100.0
AWQ67155.1\|2545751_2546168_+	phage transcriptional regulator, RinA family protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
AWQ65487.1\|2546399_2546699_+	HNH endonuclease family protein	A0EWY8	Staphylococcus_phage	4.6e-52	100.0
AWQ65678.1\|2546829_2547174_+	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
AWQ65620.1\|2547170_2548832_+	phage Terminase family protein	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
AWQ66497.1\|2548847_2550035_+\|portal	phage portal protein, HK97 family	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
AWQ66076.1\|2550018_2550756_+\|protease	clp protease family protein	C8CH20	Staphylococcus_phage	2.3e-129	100.0
AWQ65539.1\|2550779_2551925_+\|capsid	phage major capsid protein, HK97 family	A0A1X9H072	Staphylococcus_phage	5.6e-215	100.0
AWQ65461.1\|2551944_2552229_+	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
AWQ66843.1\|2552218_2552503_+\|head,tail	phage gp6-like head-tail connector family protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
AWQ65475.1\|2552486_2552849_+\|head,tail	phage head-tail joining family protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
AWQ66246.1\|2552845_2553250_+	hypothetical protein	A0A2I6PDJ6	Staphylococcus_phage	4.3e-69	100.0
AWQ67074.1\|2553246_2553654_+	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
AWQ66651.1\|2553654_2554299_+\|tail	phage major tail, phi13 family protein	W5R9H4	Staphylococcus_phage	6.5e-120	100.0
AWQ65803.1\|2554424_2554565_+	bacterial Ig-like domain family protein	W5R8L9	Staphylococcus_phage	1.1e-16	100.0
AWQ65824.1\|2554614_2554965_+	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
AWQ66383.1\|2555018_2555153_+	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	9.6e-18	100.0
AWQ67391.1\|2555209_2559739_+\|tail	phage tail tape measure protein, TP901 family, core region	A0A1X9H084	Staphylococcus_phage	0.0e+00	100.0
AWQ65281.1\|2559735_2561220_+\|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	1.2e-297	100.0
AWQ66476.1\|2561235_2565018_+	phage minor structural, N-terminal region domain protein	A0A1V0E5H3	Staphylococcus_phage	0.0e+00	99.4
AWQ65560.1\|2565010_2565163_+	putative phage protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
AWQ67241.1\|2565208_2565496_+	putative phage protein	C5I682	Staphylococcus_phage	9.9e-44	100.0
AWQ66206.1\|2565551_2565926_+	putative membrane protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
AWQ67543.1\|2566110_2566245_+	putative membrane protein	T2A9I6	Staphylococcus_phage	5.5e-13	100.0
AWQ67551.1\|2566456_2566711_+\|holin	holin, phage phi LC3 family	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
AWQ65723.1\|2566722_2567478_+	CHAP domain protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
AWQ65949.1\|2567668_2568160_+	staphylokinase	A0A1X9H028	Staphylococcus_phage	9.5e-87	100.0
AWQ65633.1\|2568848_2569145_+	bacterial SH3 domain protein	A0A1P8L6B4	Staphylococcus_phage	1.3e-51	100.0
AWQ65947.1\|2569239_2569689_-	chemotaxis inhibitory protein	A0A1P8L6A8	Staphylococcus_phage	2.1e-77	99.3
AWQ66813.1\|2570370_2570721_+	complement inhibitor	A7TWS0	Staphylococcus_phage	7.5e-54	100.0
AWQ66842.1\|2570773_2570965_-	putative membrane protein	M9NS66	Staphylococcus_phage	1.7e-23	100.0
AWQ65922.1\|2571344_2571524_-	putative membrane protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
AWQ65709.1\|2571895_2572093_-	phospholipase C domain protein	A0A1P8L6A7	Staphylococcus_phage	3.4e-27	100.0
AWQ67235.1\|2572481_2574230_+	protein map	NA	NA	NA	NA
AWQ67239.1\|2574240_2574531_+	MAP domain protein	NA	NA	NA	NA
AWQ65952.1\|2574854_2576141_-	aminotransferase class I and II family protein	NA	NA	NA	NA
AWQ66114.1\|2576681_2576858_+	putative membrane protein	NA	NA	NA	NA
AWQ66119.1\|2577116_2577497_+	bacterial regulatory, gntR family protein	NA	NA	NA	NA
AWQ66765.1\|2577493_2578390_+	ABC transporter family protein	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
AWQ66992.1\|2578390_2579071_+	ABC-2 transporter family protein	NA	NA	NA	NA
AWQ67597.1\|2579067_2579940_+	ABC transporter family protein	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
AWQ65416.1\|2579939_2580680_+	ABC-2 transporter family protein	NA	NA	NA	NA
AWQ67715.1\|2580745_2581309_-	putative thioredoxin	NA	NA	NA	NA
AWQ67286.1\|2581429_2581954_+	hypothetical protein	NA	NA	NA	NA
AWQ67432.1\|2582013_2582571_+	hypothetical protein	NA	NA	NA	NA
AWQ65718.1\|2582567_2583410_+	hypothetical protein	NA	NA	NA	NA
AWQ66988.1\|2583466_2584507_-	6-aminopenicillanic acid acyl-transferase family protein	NA	NA	NA	NA
AWQ65750.1\|2584957_2585131_+	hypothetical protein	NA	NA	NA	NA
AWQ66345.1\|2585187_2585400_-	yolD-like family protein	NA	NA	NA	NA
AWQ67387.1\|2585678_2586791_+\|integrase	phage integrase, N-terminal SAM-like domain protein	P97010	Streptococcus_pyogenes_phage	8.7e-11	31.0
AWQ67285.1\|2586793_2588857_+\|integrase	phage integrase family protein	NA	NA	NA	NA
AWQ66702.1\|2588865_2589231_+	putative cTP synthase	NA	NA	NA	NA
AWQ66411.1\|2589259_2589670_-	yolD-like family protein	U3PG23	Staphylococcus_phage	1.4e-30	54.2
AWQ66290.1\|2590160_2591840_+\|transposase	transposase DDE domain protein	A0ZS58	Staphylococcus_virus	1.9e-243	77.4
2598504:2598521	attR	NA	NA	NA	NA

DBSCAN-SWA_8

2675519 : 2728021

Staphylococcus_phage(90.48%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ65474.1\|2675519_2675990_+\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
AWQ67624.1\|2676147_2676747_+	glucosamine-6-phosphate isomerase family protein	NA	NA	NA	NA
AWQ66517.1\|2676771_2676924_+	hypothetical protein	NA	NA	NA	NA
AWQ66613.1\|2677757_2678153_+	putative membrane protein	NA	NA	NA	NA
AWQ66603.1\|2678348_2679734_+	fumarate hydratase, class II	NA	NA	NA	NA
AWQ66361.1\|2680186_2681008_-	RNA pseudouridylate synthase family protein	NA	NA	NA	NA
AWQ67077.1\|2681170_2682283_+	histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein	NA	NA	NA	NA
AWQ67207.1\|2682304_2682928_+	response regulator	NA	NA	NA	NA
AWQ66060.1\|2683283_2683748_+	helix-turn-helix family protein	NA	NA	NA	NA
AWQ65815.1\|2683926_2685051_+	hypothetical protein	NA	NA	NA	NA
AWQ67126.1\|2685119_2685464_+	hypothetical protein	A0A1X9I5Y8	Streptococcus_phage	7.5e-06	29.7
AWQ66650.1\|2686345_2687542_+	calcineurin-like phosphoesterase superfamily domain protein	NA	NA	NA	NA
AWQ65603.1\|2687531_2690468_+	AAA domain protein	NA	NA	NA	NA
AWQ67406.1\|2690464_2691406_+	3'-5' exoribonuclease YhaM	NA	NA	NA	NA
AWQ66780.1\|2691526_2692489_-	foldase protein PrsA	NA	NA	NA	NA
AWQ67111.1\|2692693_2693251_-	hypothetical protein	NA	NA	NA	NA
AWQ65482.1\|2693983_2694349_-	hypothetical protein	NA	NA	NA	NA
AWQ67051.1\|2694490_2694913_-	protein hit	NA	NA	NA	NA
AWQ67567.1\|2695046_2695787_+	ABC transporter family protein	A0A2H4PQG7	Staphylococcus_phage	2.0e-24	29.8
AWQ66981.1\|2695779_2697003_+	bacterial ABC transporter EcsB family protein	NA	NA	NA	NA
AWQ67525.1\|2697126_2697630_-	signal transduction protein TRAP	NA	NA	NA	NA
AWQ66528.1\|2697892_2698930_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
AWQ66554.1\|2698987_2699911_+	ferrochelatase	NA	NA	NA	NA
AWQ66794.1\|2699934_2701335_+	protoporphyrinogen oxidase	NA	NA	NA	NA
AWQ65778.1\|2701655_2702210_+	serine hydrolase family protein	NA	NA	NA	NA
AWQ65224.1\|2703578_2704343_+	toxin beta-grasp domain protein	A0A1X9H080	Staphylococcus_phage	2.3e-31	37.1
AWQ67280.1\|2704623_2705343_+	toxin beta-grasp domain protein	A0A1X9H080	Staphylococcus_phage	2.3e-25	35.8
AWQ65232.1\|2705377_2706106_+	toxin beta-grasp domain protein	A0A1X9H080	Staphylococcus_phage	1.1e-27	39.2
AWQ65631.1\|2706634_2707030_+	enterotoxin type C-1	A0A097PAT7	Streptococcus_pyogenes_phage	1.5e-26	50.4
AWQ67106.1\|2707326_2707824_+	enterotoxin H	A0A075M4C7	Staphylococcus_phage	8.0e-33	44.8
AWQ65705.1\|2708106_2708883_+	enterotoxin type G	NA	NA	NA	NA
AWQ65921.1\|2709434_2710211_-	hypothetical protein	NA	NA	NA	NA
AWQ67298.1\|2710231_2710468_-	hypothetical protein	NA	NA	NA	NA
AWQ67095.1\|2710545_2711040_-	hypothetical protein	NA	NA	NA	NA
AWQ65840.1\|2711567_2711696_-\|transposase	transposase family protein	A0A2H4PQU1	Staphylococcus_phage	6.6e-08	66.7
AWQ67270.1\|2711873_2712662_-	hypothetical protein	A0A2H4PQI0	Staphylococcus_phage	1.3e-138	95.0
AWQ67307.1\|2714025_2714961_+	leucotoxin LukEv	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
AWQ65661.1\|2714962_2715946_+	leucotoxin LukDv	A0A2H4PQH7	Staphylococcus_phage	1.8e-185	99.4
AWQ67296.1\|2716204_2716330_+	hypothetical protein	NA	NA	NA	NA
AWQ67591.1\|2716316_2717108_-	hypothetical protein	NA	NA	NA	NA
AWQ66364.1\|2717112_2717586_-	hypothetical protein	NA	NA	NA	NA
AWQ67463.1\|2717787_2718060_+	putative membrane protein	A0A2H4PQH0	Staphylococcus_phage	2.2e-32	84.7
AWQ67495.1\|2718533_2719112_-	hypothetical protein	A0A2H4PQH6	Staphylococcus_phage	1.9e-49	59.6
AWQ66166.1\|2720075_2720783_+\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	1.6e-127	97.9
AWQ67728.1\|2720907_2721630_+\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	6.4e-132	100.0
AWQ65638.1\|2721687_2722407_+\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.2e-130	99.2
AWQ65491.1\|2722527_2723247_+\|protease	serine protease SplF	A0A2H4PQP9	Staphylococcus_phage	5.1e-129	99.2
AWQ67637.1\|2723404_2724121_+\|protease	serine protease SplF	A0A2H4PQN5	Staphylococcus_phage	2.4e-131	99.2
AWQ67392.1\|2724271_2724991_+\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.0e-129	98.3
AWQ65321.1\|2725353_2726910_+	type I restriction-modification system, M subunit	A0A2H4PQP4	Staphylococcus_phage	2.6e-287	99.0
AWQ66333.1\|2726902_2728021_+	type I restriction modification DNA specificity domain protein	A0A2H4PQP5	Staphylococcus_phage	7.6e-39	35.1

DBSCAN-SWA_9

2733254 : 2781081

Staphylococcus_phage(90.0%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AWQ66269.1\|2733254_2733812_+	hypothetical protein	A0A2H4PQN8	Staphylococcus_phage	3.1e-78	97.5
AWQ65754.1\|2734009_2734582_-	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	1.6e-24	93.1
AWQ67003.1\|2734682_2735024_-	hypothetical protein	A0A2H4PQN6	Staphylococcus_phage	3.9e-55	95.6
AWQ66871.1\|2735064_2735691_-	putative lipoprotein	A0A2H4PQM7	Staphylococcus_phage	1.3e-88	91.3
AWQ65616.1\|2735764_2736760_-	hypothetical protein	A0A2H4PQN2	Staphylococcus_phage	9.6e-70	94.4
AWQ66425.1\|2736840_2737455_-	excalibur calcium-binding domain protein	A0A2H4PQM8	Staphylococcus_phage	1.9e-47	98.0
AWQ67452.1\|2737766_2738249_+	hypothetical protein	A0A2H4PQN7	Staphylococcus_phage	8.4e-80	99.3
AWQ65843.1\|2738407_2739886_+	O-succinylbenzoate-CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.5e-284	98.2
AWQ67090.1\|2739890_2740892_+	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.1e-188	98.8
AWQ65504.1\|2740888_2741146_-	putative membrane protein insertion efficiency factor	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
AWQ66193.1\|2741205_2741685_+	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	1.7e-85	100.0
AWQ66382.1\|2741665_2742436_+	prolyl oligopeptidase family protein	A0A2H4PQM6	Staphylococcus_phage	4.6e-144	100.0
AWQ65287.1\|2742688_2744281_-	phosphoenolpyruvate carboxykinase	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
AWQ67292.1\|2744652_2745846_+	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
AWQ65556.1\|2745970_2746879_+	nuclease-related domain protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
AWQ67204.1\|2747090_2747924_+	aldo/keto reductase family protein	A0A2H4PQR8	Staphylococcus_phage	3.5e-158	99.6
AWQ65736.1\|2747986_2748298_-\|transposase	transposase DDE domain protein	Q9MBP7	Staphylococcus_prophage	3.6e-47	92.2
AWQ67102.1\|2748316_2748670_-\|transposase	transposase DDE domain protein	A0A146ICT8	Staphylococcus_phage	7.3e-65	96.6
AWQ67514.1\|2749108_2749363_-	hypothetical protein	A0A146ICT8	Staphylococcus_phage	9.0e-41	98.8
AWQ66703.1\|2749921_2750275_-	crcB-like family protein	A0A2H4PQQ7	Staphylococcus_phage	1.0e-21	94.9
AWQ67113.1\|2750271_2750637_-	crcB-like family protein	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
AWQ65700.1\|2750892_2751195_-	putative membrane protein	NA	NA	NA	NA
AWQ67093.1\|2751454_2752168_+	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
AWQ65554.1\|2752607_2753243_-\|protease	CAAX protease self-immunity family protein	NA	NA	NA	NA
AWQ66174.1\|2753538_2753982_+	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
AWQ67063.1\|2753968_2754412_-	comK family protein	NA	NA	NA	NA
AWQ67687.1\|2754524_2754995_-	RNA polymerase sigma factor SigS	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
AWQ66442.1\|2755193_2755418_+	hypothetical protein	NA	NA	NA	NA
AWQ67585.1\|2755693_2756548_+	mannosyl-glycoendo-beta-N-acetylglucosaminidase family protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
AWQ67681.1\|2756634_2757927_-	arsenite/antimonite efflux pump membrane family protein	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
AWQ65893.1\|2758763_2760266_+	FAD-NAD(P)-binding family protein	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
AWQ67174.1\|2760746_2761790_+	riboflavin biosynthesis protein RibD	A0A2H4PQS8	Staphylococcus_phage	5.3e-196	98.8
AWQ66796.1\|2761796_2762429_+	riboflavin synthase, alpha subunit	A0A2H4PQS5	Staphylococcus_phage	1.7e-112	99.5
AWQ66021.1\|2762439_2763621_+	riboflavin biosynthesis protein RibBA	A0A2H4PQS2	Staphylococcus_phage	6.6e-227	99.7
AWQ66259.1\|2763633_2764098_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	5.8e-70	99.4
AWQ67698.1\|2764219_2765221_-	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
AWQ65845.1\|2765454_2766282_+	alpha/beta hydrolase family protein	NA	NA	NA	NA
AWQ67067.1\|2766628_2767120_+	hypothetical protein	A0A146ICT8	Staphylococcus_phage	2.4e-74	91.6
AWQ67043.1\|2767116_2767425_+\|transposase	putative transposase	Q9MBP7	Staphylococcus_prophage	3.1e-19	80.3
AWQ66566.1\|2767501_2767627_+	hypothetical protein	NA	NA	NA	NA
AWQ67024.1\|2767861_2768263_+	HTH-type transcriptional regulator rot	NA	NA	NA	NA
AWQ67013.1\|2768382_2768946_-	rRNA methylase family protein	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
AWQ65901.1\|2768942_2769896_-	radical SAM superfamily protein	A0A2H4PQV5	Staphylococcus_phage	6.4e-79	99.3
AWQ65285.1\|2770005_2771187_+	major Facilitator Superfamily protein	A0A2H4PQR6	Staphylococcus_phage	5.6e-218	100.0
AWQ65550.1\|2771477_2773898_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.7
AWQ67224.1\|2773919_2774231_+	rhodanese-like domain protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
AWQ67179.1\|2774556_2781081_+	sasC/Mrp/FmtB intercellular aggregation domain protein	A0A2H4PQU6	Staphylococcus_phage	2.2e-308	98.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP029649

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection