CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
CP025561	Listeria monocytogenes strain PIR00545 plasmid pPIR00545, complete sequence	0 crisprs	cas5,csa3	0	0	1	0
CP025560	Listeria monocytogenes strain PIR00545 chromosome, complete genome	4 crisprs	DinG,cas3,WYL,casR,cas6,cas8b2,cas7,cas5,cas4,cas1,cas2,DEDDh,csa3	1	25	7	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 54223

Streptococcus_phage(19.23%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU91384.1\|268_1138_+\|transposase	IS3 family transposase	Q6J1X2	Lactobacillus_phage	7.1e-69	51.1
AVU91385.1\|1227_1944_-	AP2 domain-containing protein	O03945	Lactobacillus_phage	3.8e-20	31.0
AVU91386.1\|1959_2682_-	CRISPR-associated protein Cas5	NA	NA	NA	NA
AVU91387.1\|2685_3111_-	hypothetical protein	NA	NA	NA	NA
AVU91388.1\|3111_3360_-	hypothetical protein	NA	NA	NA	NA
AVU91389.1\|3481_3970_-	hypothetical protein	NA	NA	NA	NA
AVU91390.1\|4128_4512_-	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	2.2e-14	53.4
AVU91391.1\|4524_5187_-	DUF2786 domain-containing protein	NA	NA	NA	NA
AVU91392.1\|5186_5513_-	hypothetical protein	A0A2K9V3N4	Faecalibacterium_phage	3.2e-06	40.8
AVU91393.1\|5643_5895_+	hypothetical protein	NA	NA	NA	NA
AVU91394.1\|5955_6198_+	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
AVU91395.1\|6191_6533_+	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
AVU91396.1\|6725_8861_-	cadmium-transporting ATPase	E4ZFI9	Streptococcus_phage	1.6e-247	64.5
AVU91397.1\|8860_9220_-	cadmium resistance transcriptional regulator CadC	E4ZFI8	Streptococcus_phage	3.1e-26	50.0
AVU91398.1\|9499_10054_+	resolvase	A0A0A7NPV4	Enterobacteria_phage	5.4e-38	46.1
AVU91399.1\|10057_12973_+\|transposase	DDE transposase	A0A1B0V7H9	Salmonella_phage	1.9e-174	36.7
AVU91400.1\|14155_16312_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.1e-70	31.0
AVU91401.1\|16527_17091_+	transposon DNA-invertase	A0A0A7NPV4	Enterobacteria_phage	2.0e-40	51.1
AVU91402.1\|17341_18553_+	hypothetical protein	NA	NA	NA	NA
AVU91403.1\|18545_20399_+	DUF87 domain-containing protein	NA	NA	NA	NA
AVU91404.1\|20883_21525_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	3.0e-101	83.6
AVU91441.1\|21644_23528_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	5.6e-87	35.3
AVU91405.1\|23990_24782_-	hypothetical protein	NA	NA	NA	NA
AVU91406.1\|24945_25266_-	hypothetical protein	NA	NA	NA	NA
AVU91407.1\|25265_25505_-	hypothetical protein	NA	NA	NA	NA
AVU91408.1\|25625_26495_+	glycine/betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
AVU91409.1\|26740_28105_-	oxidoreductase	A0A2K5B2C5	Erysipelothrix_phage	1.9e-07	23.5
AVU91410.1\|28728_29409_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	2.6e-119	90.7
AVU91411.1\|29974_31477_-	hypothetical protein	H2DE57	Erwinia_phage	5.2e-11	46.0
AVU91412.1\|31480_31879_-	hypothetical protein	NA	NA	NA	NA
AVU91413.1\|32052_32388_+	XRE family transcriptional regulator	A0A139ZPK3	Marinitoga_camini_virus	2.8e-05	35.0
AVU91414.1\|32424_32955_-	hypothetical protein	NA	NA	NA	NA
AVU91415.1\|33068_33833_-	Fic family protein	A0A0G3Y4Q5	Ostreid_herpesvirus	2.6e-06	29.4
AVU91416.1\|33852_34224_-	hypothetical protein	NA	NA	NA	NA
AVU91417.1\|34234_35575_-	hypothetical protein	NA	NA	NA	NA
AVU91418.1\|35567_36008_-	hypothetical protein	NA	NA	NA	NA
AVU91419.1\|36019_36259_-	hypothetical protein	NA	NA	NA	NA
AVU91420.1\|36656_37574_-	hypothetical protein	NA	NA	NA	NA
AVU91421.1\|37576_37966_-	hypothetical protein	NA	NA	NA	NA
AVU91422.1\|37928_38165_-	hypothetical protein	NA	NA	NA	NA
AVU91423.1\|38180_38297_-	hypothetical protein	NA	NA	NA	NA
AVU91424.1\|38508_39735_+\|transposase	IS21 family transposase	A0A059NT83	Lactococcus_phage	4.7e-135	60.6
AVU91425.1\|39703_40501_+\|transposase	transposase	A0A059NT77	Lactococcus_phage	3.3e-81	63.2
AVU91426.1\|40577_41180_+	DDE domain-containing protein	U5P429	Shigella_phage	2.0e-33	41.7
AVU91427.1\|41213_41969_-	hypothetical protein	NA	NA	NA	NA
AVU91428.1\|42243_43878_-	plasmid replication protein	NA	NA	NA	NA
AVU91429.1\|44617_45592_+	chromosome partitioning protein ParA	F0PIG8	Enterococcus_phage	2.4e-33	35.0
AVU91430.1\|45569_45866_+	replication and copy control-associated protein	NA	NA	NA	NA
AVU91431.1\|45916_47197_-	excinuclease ABC subunit A	O64031	Bacillus_phage	5.2e-92	44.9
AVU91432.1\|47184_47529_-	hypothetical protein	NA	NA	NA	NA
AVU91442.1\|47733_48468_-	ParA family protein	NA	NA	NA	NA
AVU91433.1\|48642_49983_-\|transposase	transposase	A0A0C5AC89	Paenibacillus_phage	1.1e-31	38.6
AVU91434.1\|50258_52373_-\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	3.4e-117	39.1
AVU91443.1\|52800_53037_-	XRE family transcriptional regulator	A0A097PBE6	Streptococcus_pyogenes_phage	6.7e-14	53.4
AVU91444.1\|52999_53278_+	hypothetical protein	NA	NA	NA	NA
AVU91435.1\|53397_53625_-	hypothetical protein	NA	NA	NA	NA
AVU91436.1\|53614_54223_-	recombinase family protein	A0A1W5LU24	Ralstonia_phage	1.0e-21	42.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. CP025560

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CRISPR-Cas detection and classification

Crispr_ID: CP025560_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025560_1

531896-532119

Unclear

I-A

Consensus_repeat	Method
GTTTTAGTTACTTATTGTGAAATGTAAATTT	PILER-CR
TTTTAGTTACTTATTGTGAAATGTAAAT	CRISPRCasFinder

3 spacers

cas6,cas8b2

The CRISPR arrays of CP025560_1

>merge|CP025560|1|531896-532119|PILER-CR,CRISPRCasFinder
GTTTTAGTTACTTATTGTGAAATGTAAATTTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAAGTTTTAGTTACTTATTGTGAAATGTAAATTTTTCTACTCCTGCTTCTAAAATGTCGTTTATAAGTTTTAGTTACTTATTGTGAAATGTAAATCTAAAACATCCTTCACTGTATCAACTCCTTTCTATATTTTAGTTACTTATTGTGAAATGTAAATTT

>CP025560|1|1|531896-532119|PILER-CR
GTTTTAGTTACTTATTGTGAAATGTAAATTT	TATTTCTCCTACGCTTTTCTTATTTCTGTAAATAA
GTTTTAGTTACTTATTGTGAAATGTAAATTT	TTCTACTCCTGCTTCTAAAATGTCGTTTATAA
GTTTTAGTTACTTATTGTGAAATGTAAATCT	AAAACATCCTTCACTGTATCAACTCCTTTCTAT
ATTTTAGTTACTTATTGTGAAATGTAAATTT

>CP025560|1|1|531897-532117|CRISPRCasFinder
TTTTAGTTACTTATTGTGAAATGTAAAT	TTTATTTCTCCTACGCTTTTCTTATTTCTGTAAATAAG
TTTTAGTTACTTATTGTGAAATGTAAAT	TTTTCTACTCCTGCTTCTAAAATGTCGTTTATAAG
TTTTAGTTACTTATTGTGAAATGTAAAT	CTAAAACATCCTTCACTGTATCAACTCCTTTCTATA
TTTTAGTTACTTATTGTGAAATGTAAAT

Protein	Signature genes	Signature genes Name	Protein_function
CP025560.1\|AVU88903.1\|525773_526376_+\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223865
CP025560.1\|AVU88916.1\|537519_538950_-\|capsule-biosynthesis-protein-CapA	unknown	unknown	gnl\|CDD\|225399
CP025560.1\|AVU88911.1\|532508_533087_+\|hypothetical-protein	unknown	unknown	unknown
CP025560.1\|AVU88914.1\|534265_534724_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378956
CP025560.1\|AVU88915.1\|535105_536941_+\|lmo0514-family-class-1-internalin	unknown	unknown	gnl\|CDD\|380190
CP025560.1\|AVU88906.1\|527296_527947_+\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|223114
CP025560.1\|AVU88909.1\|529313_530585_+\|PTS-galactitol-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|226298
CP025560.1\|AVU88917.1\|539070_539886_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
CP025560.1\|AVU88901.1\|522950_523601_+\|transaldolase	unknown	unknown	gnl\|CDD\|223254
CP025560.1\|AVU88905.1\|526887_527286_+\|hypothetical-protein	unknown	unknown	unknown
CP025560.1\|AVU88912.1\|533194_533875_+\|GMP-synthase	unknown	unknown	gnl\|CDD\|153212
CP025560.1\|AVU88913.1\|533899_534259_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|131113
CP025560.1\|AVU88904.1\|526403_526871_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|238129
CP025560.1\|AVU88919.1\|540976_542665_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09754_cas8b2_CAS-I-B	gnl\|CDD\|187884
CP025560.1\|AVU88902.1\|523709_525770_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|226234
CP025560.1\|AVU88907.1\|527943_528990_+\|galactitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|176198
CP025560.1\|AVU88910.1\|530724_531660_+\|ribose-phosphate-pyrophosphokinase	unknown	unknown	gnl\|CDD\|234929
CP025560.1\|AVU88908.1\|529005_529299_+\|PTS-galactitol-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|99908
CP025560.1\|AVU91329.1\|537041_537473_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
CP025560.1\|AVU88918.1\|540238_540961_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|273848

Protein	Function_ID	Function_description	E-value
CP025560.1\|AVU88903.1\|525773_526376_+\|SIS-domain-containing-protein	gnl\|CDD\|223865	COG0794, GutQ, Predicted sugar phosphate isomerase involved in capsule formation [Cell envelope biogenesis, outer membrane].	2.80915e-75
CP025560.1\|AVU88916.1\|537519_538950_-\|capsule-biosynthesis-protein-CapA	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	3.18655e-101
CP025560.1\|AVU88917.1\|539070_539886_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.01016e-50
CP025560.1\|AVU88914.1\|534265_534724_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|378956	pfam12802, MarR_2, MarR family. The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.	1.03599e-12
CP025560.1\|AVU88915.1\|535105_536941_+\|lmo0514-family-class-1-internalin	gnl\|CDD\|380190	NF033186, internalin_K, class 1 internalin InlK. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. Members of this family are internalin K (InlK), a virulence factor. See articles PMID:17764999. for a general discussion of internalins, and PMID:21829365, PMID:22082958, and PMID:23958637 for more information about internalin K.	1.00483e-119
CP025560.1\|AVU88906.1\|527296_527947_+\|ribulose-phosphate-3-epimerase	gnl\|CDD\|223114	COG0036, Rpe, Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism].	4.74405e-108
CP025560.1\|AVU88909.1\|529313_530585_+\|PTS-galactitol-transporter-subunit-IIC	gnl\|CDD\|226298	COG3775, GatC, Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism].	7.01085e-178
CP025560.1\|AVU88901.1\|522950_523601_+\|transaldolase	gnl\|CDD\|223254	COG0176, MipB, Transaldolase [Carbohydrate transport and metabolism].	5.85703e-62
CP025560.1\|AVU88912.1\|533194_533875_+\|GMP-synthase	gnl\|CDD\|153212	cd01741, GATase1_1, Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. This group contains a subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain. GATase activity catalyses the transfer of ammonia from the amide side chain of glutamine to an acceptor substrate. Glutamine amidotransferases (GATase) includes the triad family of amidotransferases which have a conserved Cys-His-Glu catalytic triad in the glutaminase active site. In this subgroup this triad is conserved. GATase activity can be found in a range of biosynthetic enzymes, including: glutamine amidotransferase, formylglycinamide ribonucleotide, GMP synthetase , anthranilate synthase component II, glutamine-dependent carbamoyl phosphate synthase, cytidine triphosphate synthetase, gamma-glutamyl hydrolase, imidazole glycerol phosphate synthase and, cobyric acid synthase. Glutamine amidotransferase (GATase) domains can occur either as single polypeptides, as in glutamine amidotransferases, or as domains in a much larger multifunctional synthase protein, such as CPSase.	9.06055e-60
CP025560.1\|AVU88913.1\|533899_534259_-\|hypothetical-protein	gnl\|CDD\|131113	TIGR02058, lin0512_fam, conserved hypothetical protein. This family consists of few members, broadly distributed. It occurs so far in several Firmicutes (twice in Oceanobacillus), one Cyanobacterium, one alpha Proteobacterium, and (with a long prefix) in plants. The function is unknown. The alignment includes a perfectly conserved motif GxGxDxHG near the N-terminus. [Hypothetical proteins, Conserved].	5.62162e-67
CP025560.1\|AVU88904.1\|526403_526871_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|238129	cd00211, PTS_IIA_fru, PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family is one of four structurally and functionally distinct group IIA PTS system cytoplasmic enzymes, necessary for the uptake of carbohydrates across the cytoplasmic membrane and their phosphorylation.	4.11384e-37
CP025560.1\|AVU88919.1\|540976_542665_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187884	cd09754, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	6.40364e-26
CP025560.1\|AVU88902.1\|523709_525770_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	5.36772e-80
CP025560.1\|AVU88907.1\|527943_528990_+\|galactitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|176198	cd08236, sugar_DH, NAD(P)-dependent sugar dehydrogenases. This group contains proteins identified as sorbitol dehydrogenases and other sugar dehydrogenases of the medium-chain dehydrogenase/reductase family (MDR), which includes zinc-dependent alcohol dehydrogenase and related proteins. Sorbitol and aldose reductase are NAD(+) binding proteins of the polyol pathway, which interconverts glucose and fructose. Sorbitol dehydrogenase is tetrameric and has a single catalytic zinc per subunit. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Related proteins include threonine dehydrogenase, formaldehyde dehydrogenase, and butanediol dehydrogenase. The medium chain alcohol dehydrogenase family (MDR) has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit. Horse liver alcohol dehydrogenase is a dimeric enzyme and each subunit has two domains. The NAD binding domain is in a Rossmann fold and the catalytic domain contains a zinc ion to which substrates bind. There is a cleft between the domains that closes upon formation of the ternary complex.	0
CP025560.1\|AVU88910.1\|530724_531660_+\|ribose-phosphate-pyrophosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	2.38027e-153
CP025560.1\|AVU88908.1\|529005_529299_+\|PTS-galactitol-transporter-subunit-IIB	gnl\|CDD\|99908	cd05566, PTS_IIB_galactitol, PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane channel IIC domain that are expressed on three distinct polypeptide chains, in contrast to other PTS sugar transporters. The three genes encoding these subunits (gatA, gatB, and gatC) comprise the gatCBA operon. Galactitol PTS permease takes up exogenous galactitol, releasing the phosphate ester into the cytoplasm in preparation for oxidation and further metabolism via a modified glycolytic pathway called the tagatose-6-phosphate glycolytic pathway. The IIB domain fold includes a central four-stranded parallel open twisted beta-sheet flanked by alpha-helices on both sides. The seven major PTS systems with this IIB fold include galactitol, chitobiose/lichenan, ascorbate, lactose, mannitol, fructose, and a sensory system with similarity to the bacterial bgl system.	3.06007e-27
CP025560.1\|AVU91329.1\|537041_537473_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	4.03126e-27
CP025560.1\|AVU88918.1\|540238_540961_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	5.90561e-33

>CP025560.1|AVU88910.1|530724_531660_+|ribose-phosphate-pyrophosphokinase
MAGKMKLFSVTSERPLATKIADYLDIPLCEVELQKFSDGEVKINIEESIRGTNAYVVQSMNSNVNERLMELLIMVDALKRASVHSINIIMPYYGYARQDRKARSREPITAKLMANLIQRAGANRLITVDLHAAQIQGFFNIPIDHLSAIPLIGDYLIENYGEKDVVVVAPDHSGVVRARRIADRLNAPIAILNRKPRPHEDEIMSVIGDVKGKVAIVVDDIIDTGVRATTSADILLEKGAVEVIACATHSVMAGNATERLQNSSIKEVITSDSIDLPEDKQFDKLTTISIGRILGRAIEGVQENRSLHPLF
>CP025560.1|AVU88909.1|529313_530585_+|PTS-galactitol-transporter-subunit-IIC
MDIILDFFKYIIGLGVTVMMPIIITILGVIFRKKISVAFKAGLTVGVGFVGLGVITSLMLTTITPVTKALVENYNFKLTATDIGWGVGSSLAWGTEVVPFVFVAIIATNILMIAFKWTKTMDVDIWNYWQPLFIASALYLTTGSMIIAVLSSIINMAIIFKIADWTQKDVEDVLGLEGISLPQIQTTGWALVGYPMNWLLGKIPGVRKINWSTEKVQSRLGIFGEPMLMGLIIGGGLAAIAQMPLSQVLQTGVTIAASLVLIPRMVSLLMDGLTVISEAAHEFMEKRFPGRELFIGLDSAVGIGHPFVLSLGLLMIPITLILAFILPGNKVLPLADLTALPFYMIFAIVPSKGNLFRGIFTGIVIVIITLYLSGAAAPLMTELAGQIGYNIPKDAVEVTSLAVGTQWYTWIVYYGLHWFGGIL
>CP025560.1|AVU88908.1|529005_529299_+|PTS-galactitol-transporter-subunit-IIB
MKKKRIYVCCGTGIATSTVISKKVRAVLDEKRIPYEISQCTVQEVASKVSTSKPDIIVSSTTVTGDVGDVPVVIGRSFLTGLKKQETIDEILAILQD
>CP025560.1|AVU88907.1|527943_528990_+|galactitol-1-phosphate-5-dehydrogenase
MKALKLYGKRDLRYEEADMPTIEEPDDVILKVKTVGICGSDISRYSKLGPYVPGMVWGHEFSGEVIEVGSEVTDIEIGDRAAGCPALYCGECEYCKKGEFARCRKLTVIGARHPGAYAEYIKLPAENVVKIPNELDYEAAALVEPSAVVVHGFYHTKLQAGDDVVVVGSGNIGLLAIQWAKVFGARRVIAIDVDDKKLALAKEVGADVVINSLKEDPLEVVAAHTDGLNADLVVEAAGSPITSAQVFAYAKKGGGVVFLGIPYADVTIERFYFEKIVRSELTVWGSWNAISAPFPGKEWQTTIHFLANKQINIEPMITHRLSLAEGPEVFERIYERNEFFGKVLFFPE
>CP025560.1|AVU88906.1|527296_527947_+|ribulose-phosphate-3-epimerase
MAKIVPSVFGADIGRINEQLQVLEKNDIDLLHVDMMDGSFVPNIAFGPDQIKMMKKGTKLQFDVHMMVYEPDRYIPRLVEAGAHMITVHQEATTHLHRTIQLIKSYGVRAGVVLNPGTPPSTLEYVLDDIDCILLMTVNPGLGGQKFFQSSLEKIRKTKAYIGNRPIQIEVDGGVNDELAKECTLAGADLIVVGSYLFEGDIEANLEKLAKGVLTE
>CP025560.1|AVU88905.1|526887_527286_+|hypothetical-protein
MGSFFASFVDWLIGSPGRFVVNLIEDNMLIFMVVVMIYATTILYAKWTLAYYLPKKMSQLAEMKTWELDELYAAWQTEKKALPWYILVPSRNEFWVKSARNAPESTKLLHFSQQKLKLSDKEKLQKIIEIQS
>CP025560.1|AVU88904.1|526403_526871_+|PTS-sugar-transporter-subunit-IIA
MDVLEYFKEEMVRFSNEQNKEKLLVEMAEQLCEVGAVKPSYKDAVIKREKVFPTGLLTAHAGVAIPHTDSEHVIRPVVAVRILKKPVSFIEMASDNEAIDVRIVFMMALRSADEQLDMLQTLIQLIQDEEVMTTLLKAQETGDVLSAIEHFSKNN
>CP025560.1|AVU88903.1|525773_526376_+|SIS-domain-containing-protein
MDKQAILNNIHQTWQEEANAISRLPEVTSEEALVKTVEKIAECTGKIVVAGCGTSGVAAKKLVHSFNCIERPAVFLTPSDAVHGTLGVLQKEDILILISKGGNTGELLNLIPACKTKGSTLIGVTENPDSVIAKEADIFFQVSVSKEPDPFNMLATASTMAVIASFDAVIVCLMTYMNYTKEQFSVIHPGGAVGNKLLNK
>CP025560.1|AVU88902.1|523709_525770_+|PTS-sugar-transporter-subunit-IIA
MYLDNRSKTLFQEVIKNPNITNKQLEVKYKLSRYQISYSFQKVNEWLKWKNYPEVKRSKNGRFILEPELTALFSEKETRDPSVEYLPSENERANLILLMLLTSKEELSLAHFTTKIQVSKNTILRDLKVAQKLLPKETTVTYSRASGYQLAGSEWELRKVLTQVVSSVKEMFRGEHYFLSYSGIEKVQLMEIRRTLEEAEAMMQIKFTYEQIELLPYLLSVMFLRIRDRRLIDTAFHIDEKSLSDTREYHITDILLEKTGPVPEQERLFITLQLLTTNIFSGEILTEKLTEDLEKVVLTCLDLFEKKALVSLKNKHILIEKLLLHLKPAYYRIKYQMNLEDTLYEKFNQEFEALNFIVKEAFDPLAKFIGREIPAGEIFFISLFIGSDMIPQNDIYHKQKRAIVLCPSGVTFSKIMENILVKLFPEIHFYPTISVREYAFFKAEVDIVFSSIPLKDGENVFVVQPFMNDIEKTQLRQHVLQNLFGMGNQLTSIDKIMEVVERNADIKDPNAIRDGIIDILSANIATDENKRVKKVYLHDLITEDNIMICEDVKNYQEAIRLASQPLLLQQAITANYVKTMIDNHKFHDPYIIIGEDIAIPHAMPNAGVNRLAMSLLVVKNGVYFSETEQVHFVIVIAPVDKEQHIEALYQIVHLAENHQILDDLLENVTKEKIMQTINQLVIREDE
>CP025560.1|AVU88901.1|522950_523601_+|transaldolase
MHLDSANLDDVKKIQASSIFKGITTNPTILVKEKCNRQTAINRILELTDKQVFVQTVGFTYEEILADARMLLTMFGKDKIAIKIPAHEAGTNVIDTLKKEDKTIQILGTAIYSADQAITAALAGADFVAPYVNRMSAANIDPFKEITQMRHFFDKKALKTQIMAASFKHSGQVMQAYESGADTVTIPYEIYSQMTNKVLAVEAIRVFNEDAVLYEK
>CP025560.1|AVU88911.1|532508_533087_+|hypothetical-protein
MKKILVPILLLATILASCSSPNEKITKDTKISKTITIRADYKVPKDIKELEDDSANIVKVKFLQNKTIGKDGSTISEIEILTSYKGNLEKGSKVDISEPWYLSDGKYVAVENYIALDKEQEYTIFLGEKDKDTYPLSSLGYGKFGGSLKEDQAVLADFNILGEVQKFDFISENTEEVKNYQLIKEQVAGKYK
>CP025560.1|AVU88912.1|533194_533875_+|GMP-synthase
MIIDVLQHVPHEGPGLIANWARENQHQLKIHSLFEENAHVPNDSDFLIVLGGPMGINDTAEFPWLKDERKLIKRLSEQHKPVFGVCLGAQQIAATFGSEITVNKEKEVGWFPVKRTSDKLLFFPKSLNVFHWHQDTFALPTGSTRLFASEGCLNQAFLYGENIIGLQFHFEMEKAGIETILRIDEAFITPGKYVQSVEVMREKDVPEDNKQMLEAILDYLINPKTI
>CP025560.1|AVU88913.1|533899_534259_-|hypothetical-protein
MEQILFIQTGFGVDVHGQNITKAAERAVRNAIFTNSMPGIQGLLPDGDLQNMVVNIKLALPCDADQLDEDTIRAIIPYGTVTIEKMAGGMMTTSGIFLEDKEDKNDLMYIVNASVETGY
>CP025560.1|AVU88914.1|534265_534724_-|MarR-family-transcriptional-regulator
MNNEQNMNQQIALFYFGYKAFTETADLIIAKHSLKRLHHRILFFTARMPGLTINELLTFLEISKQALHQPLAELKERELLTIEQGRRDKRQRCIFLTAAGKELENELGAAQRKQMSEIFTNSADTDGMHFTEVMEGYAKNRPGAAFIKDFKE
>CP025560.1|AVU88915.1|535105_536941_+|lmo0514-family-class-1-internalin
MKKALKLFLATICMFIMIYPSTAAHAEETNIVNIPDANLKTYLNGLLKQASDAPITKTQMNTIQTVTLSGSTYTDLTGLEEAGNLVTLSINNTNIQTLEPIKNQTSLTYLTVGGDNVKDSLFVDLNGLVNLQSLSINGSEVTHNVFKTFNKLPKLTYLYAQNSMKITDISALASLPALTTLFLQFDGIDDFRPLNDFESFKNGNLKALAAFGQNTGRTNPRITLKSGKLDYNETNQTLYLPFSMMPKPLTSFDGTVAPFSKSTSASNTYLGFNDVALPSSRLSITDDGITVSGVTKEEFDNLDEIEYNARYDFPTGSYPTPPSMTSYTISSGTYDQYFDISHTLDLTADESFDYNQYDTTSEEQFLKDVHAETDDGTAVKSDFDQVVKLDVPGEYTVTLNAENAAGLKATPVTVKVTVHEKPVITSDSQISYKKETTKSVDEFLKEIHGSVTGNAVLTSDFDKVVDLNTPGEYTVTLNAINDRGQKADPVTVVVTVTTSDSGHVNPVPPTPEVKPTPQEETDQTIIPEPQSETTEDSVKEDQAKDGQAKSEEKADKTSLTTKENKVEKSEKTNQPKTKALPQTGDTNKTALPIAGVMLSLAALLIFRKSKS
>CP025560.1|AVU91329.1|537041_537473_+|universal-stress-protein
MEKYHRILVAVDGSEPAKLAFEKGLELALKLDGVLGIASIVDLRAFSPNVSYDGSLEEKAELELKTSVNEYAEKARTAGVKQVETFVAKGNPKILLSTDIPAEFQADLIICGATGMNRVEKLVLGSVSSYIMAHAICDTLIAR
>CP025560.1|AVU88916.1|537519_538950_-|capsule-biosynthesis-protein-CapA
MKKLTYVIITGLVLVFIAGAFWITNSTNQSDQKVTQTEPLKKTSPANVKTISSEAKKTLNSLASSGADKASISDLKQLIKELKSYPTEKNDSGVYLQNLTACLEAVKSYTTGKADEKALGKVYPAFLASEQKLSAIEKTNQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFQKNNGNNTYVYKNCLPWFKSDDYTVINAESAFTNATKAENKKWRIKSDPAHVAFLPASGVEAANLANNHTMDYFQVGYDDTLKAFKENNIPVFNTDAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTKEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIEGGVTEYTYFDPF
>CP025560.1|AVU88917.1|539070_539886_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDPRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGLSPKDFANSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>CP025560.1|AVU88918.1|540238_540961_+|CRISPR-associated-endoribonuclease-Cas6
MRLKINCDFDSKIIPKDFQSKVVSLFKAGIMKSSPERYENLFGGNKHKQYTFSVYLPKPQNKGAEIQLNEANCIINFSTGDAETGIIFYNALISLRGSKVLFGAGNHITVKNIQIVPEKKIIGKQTILRTLSPVVSRDHNRETFKNWFYSFEDEEFEPTLKRNMLPYLIDAFGEQARYDLEKLKITPISMKKVVVYCHEIHIESSVGIFELEAEAYLQKYLVENGIGTMTGSGFGMIEQF
>CP025560.1|AVU88919.1|540976_542665_+|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MQTEIEVRADDWLINAGLTGFLNIVGKENVRIDGQAIYFTADLLEDFETKYFNFFIQEYKETLSWYKIVSYKETMEQFRIDKFASFDEVALGNLNKYMKDVVKFYLKKANYIKVFPLIDPSANVTKWLEKLNTINLTKKQKWDEVKADIIEEVKQTYTQLDLIIDFCASEKGLQYLGAKNLIYSVINKGWSGVSFLFKQTKFIDPYLDYKTTFVDPVLEYLDTDLSKAKYNCFNCNQPIKNLKLDLSFMNDVGFDTARKTAHVWDFNNDVATCPICRLIYSCVPAGFTYVYGEGMFVNDSYGVEELHRVNERMRNSILRFNKDGINSTNTYRALVESITMEHENNRRYELADIQLVRYENEHYRFNLLSKKMLHIVNDSKGILKSLIRCGYKEGNLNVNLYKEVIQHLMNNENLFTLIHKLIYYKQTSVNGLYYNMGHVSGILDINTKFLKEMEVMTNISQNQLWFVQNCGKEFKEGYVKKKSENKISGITYKLLNSLKVNDKDGFMDTLLNSYSYLSMPIPDVFIKMFSNNEAFKSVGYAFMLGVGGEKTKKEDGGNTDEK

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Crispr_ID: CP025560_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025560_2

548544-551810

Unclear

I-A

Consensus_repeat	Method
GTTTTAACTACTTATTATGAAATGTAAAT	PILER-CR
GTTTTAACTACTTATTATGAAATGTAAAT	CRISPRCasFinder
GTTTTAACTACTTATTATGAAATGTAAAT	CRT

50 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of CP025560_2

>merge|CP025560|2|548544-551810|PILER-CR,CRISPRCasFinder,CRT
GTTTTAACTACTTATTATGAAATGTAAATCCATCCACGTGGACGGGACTTCTTTTACATCAATGTTTTAACTACTTATTATGAAATGTAAATTCAGCAAACCAATCCATTCAAGACGCCTTTGTGTTTGTTTTAACTACTTATTATGAAATGTAAATTAGTATCTCACTTCAAAACTATCTGTGTCACTATTGTTTTAACTACTTATTATGAAATGTAAATCAAGAAGCACGTAAGATGTTTGTAGCACCAGACAACGTTTTAACTACTTATTATGAAATGTAAATCAAAAAGAAGTCGTATCTGAAAATAGCAAAGCACCTCAGTTTTAACTACTTATTATGAAATGTAAATGACACTCATTTTTGCTGCTTGCTTACTAGTGACCTTTGTTTTAACTACTTATTATGAAATGTAAATACTGATAACCCTAATTTTGTAGCAATTACTGAAAGTGTTTTAACTACTTATTATGAAATGTAAATCCTGAAATGGGGGCTTTTTTGTGATGAAAAACACGTTTTAACTACTTATTATGAAATGTAAATTGGTATAAATCTAAAAATACACAAGTTGTAAATGTGTTTTAACTACTTATTATGAAATGTAAATTTACCACCAAAGTCCCTACACTCAATACCACCAAAGTTTTAACTACTTATTATGAAATGTAAATCTAAAAAAGATTGGCAGAATGGAAATGTGTATGTGTGTTTTAACTACTTATTATGAAATGTAAATCCATTACGTTTGCCTTGTTGTTAAAGCTTGCAACGTTTTAACTACTTATTATGAAATGTAAATAGCTGTAGCACCTTTCTGCAATCTTTCAGCCTCATGTTTTAACTACTTATTATGAAATGTAAATAAAGTAAATGCCGTAGAAACGTCCTCACAACCACAGTTTTAACTACTTATTATGAAATGTAAATACAAGTGGCTTAATATAAAACGTTGGTGCTGTGGGGTTTTAACTACTTATTATGAAATGTAAATTGATAACCGTCAAATAAGTCAGTGTCAACTTCGTCGTTTTAACTACTTATTATGAAATGTAAATGTTGTTTTTTATGTTTAGCATCCATAGTCGTAAGGGTTTTAACTACTTATTATGAAATGTAAATTTCGAAAAGTCTGTTTTGCCCTATGTCTAATCCTTTGTTTTAACTACTTATTATGAAATGTAAATACATTCGAAGTGGAGTGGCAACAAAAGCCTTATAGTTTTAACTACTTATTATGAAATGTAAATAAGTTAATTATTGAATGCTATCCAGAAAGAATAGAAGGTTTTAACTACTTATTATGAAATGTAAATGTGCTTAAAACGATGACAAAAGTAGGAATAACATCAGTTTTAACTACTTATTATGAAATGTAAATTTGCTTATAGAAGCTTATTTGTCTATTATTACCAGCGTTTTAACTACTTATTATGAAATGTAAATGTTGAAAAGCGCACCATTGTTTTAATTTTTTTAATTGTTTTAACTACTTATTATGAAATGTAAATTTTTGTCGCATAAATTCTTTGATGTGGCGGACTGACGGTTTTAACTACTTATTATGAAATGTAAATAACAGTATCATCACGTTGTTATTGCTGTCACCTGTGTTTTAACTACTTATTATGAAATGTAAATACGGGTACCAGCTTTGATTTGCTGTTTTCAATTATTGTTTTAACTACTTATTATGAAATGTAAATTTTATCACTCCTATGCTTTTCTTATTTCTGTAAATGTTTTAACTACTTATTATGAAATGTAAATGCTTTTTTCAACAATTTTATCACCAGATGTCATTAGTTTTAACTACTTATTATGAAATGTAAATTGAGCAGTGTCACCTGTTTCCGTATCTGCTTTTTTCGTTTTAACTACTTATTATGAAATGTAAATATAGATTAGTAGGGAAATAATATGTAATGGTTACTGGTTTTAACTACTTATTATGAAATGTAAATAAGAAATCCGGGAAGTTTTGTTCTACAGAGCGAACGGGTTTTAACTACTTATTATGAAATGTAAATCTTCTTAACCCTTTAACACAAGCGCAAGATGGCTGTGTTTTAACTACTTATTATGAAATGTAAATTTAATAAATCCGATGGTGATGCCTATGTTATACGTCGTTTTAACTACTTATTATGAAATGTAAATTAAAACATCGCTTCGTTATACAATGTCTTTTTATAGTTTTAACTACTTATTATGAAATGTAAATTGTTATCTCCTGTGATGTAAAATAACCCTTCTATCGTTTTAACTACTTATTATGAAATGTAAATCTTGTTAAGTCCCCACTTCCATTAAAATCGTAATTGTGTTTTAACTACTTATTATGAAATGTAAATGTGTAATTCTTAATTCCGTATTGATTCGCTAGTTTTGTTTTAACTACTTATTATGAAATGTAAATACAATTAACACATTGTCAGTTCTGGTCTGGTATGTTTGTTTTAACTACTTATTATGAAATGTAAATTTGTTTATATGCACATAAATTTCGCGCATCCATAACGTTTTACTACTTATTATGAAATGTAAATTTTATACGTATGAGTCCGTCATATCGCATATTTAGTTTTAACTACTTATTATGAAATGTAAATAAAGGTAAAAATATTCTTGCTGTGGCAGGTCCTGATGTTTTAACTACTTATTATGAAATGTAAATCTCTTCCACTTTTGCTGCTTTTTCCGCATCTGGTACAAGTTTTAACTACTTATTATGAAATGTAAATATTACTTAATTCTAGTTACGTTGCTGCGTTTACTTCTGTTTTAACTACTTATTATGAAATGTAAATAAATTTTTTGTTGATAAGCATGCAGGAGCAAATAAGTTTTAACTACTTATTATGAAATGTAAATCAGTGATTATGCTAAGACCTACACAATCGTTATCACTGTTTTAACTACTTATTATGAAATGTAAATAGAGAAATCTCAAGAGCCAGCCAAGCAAGAGACATCGTTTTAACTACTTATTATGAAATGTAAATGGCTTTCTGGAATTGTTTCGCTGACATCCCTGCCAGGTTTTAACTACTTATTATGAAATGTAAATCAAAACAGAGAACGCGTGTTCATTATCGGACATCTTAGTTTTAACTACTTATTATGAAATGTAAATTTTTGAAATATGAGGACTTAGAAAATGAAAAAAATGTTTTAACTACTTATTATGAAATGTAAATAAAAACTATGCAATTAGCAAAGTGATTTTATGTAATTGTTTTAACTACTTATTATGAAATCATAAA

>CP025560|2|2|548544-551744|PILER-CR
GTTTTAACTACTTATTATGAAATGTAAAT	CCATCCACGTGGACGGGACTTCTTTTACATCAAT
GTTTTAACTACTTATTATGAAATGTAAAT	TCAGCAAACCAATCCATTCAAGACGCCTTTGTGTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TAGTATCTCACTTCAAAACTATCTGTGTCACTATT
GTTTTAACTACTTATTATGAAATGTAAAT	CAAGAAGCACGTAAGATGTTTGTAGCACCAGACAAC
GTTTTAACTACTTATTATGAAATGTAAAT	CAAAAAGAAGTCGTATCTGAAAATAGCAAAGCACCTCA
GTTTTAACTACTTATTATGAAATGTAAAT	GACACTCATTTTTGCTGCTTGCTTACTAGTGACCTTT
GTTTTAACTACTTATTATGAAATGTAAAT	ACTGATAACCCTAATTTTGTAGCAATTACTGAAAGT
GTTTTAACTACTTATTATGAAATGTAAAT	CCTGAAATGGGGGCTTTTTTGTGATGAAAAACAC
GTTTTAACTACTTATTATGAAATGTAAAT	TGGTATAAATCTAAAAATACACAAGTTGTAAATGT
GTTTTAACTACTTATTATGAAATGTAAAT	TTACCACCAAAGTCCCTACACTCAATACCACCAAA
GTTTTAACTACTTATTATGAAATGTAAAT	CTAAAAAAGATTGGCAGAATGGAAATGTGTATGTGT
GTTTTAACTACTTATTATGAAATGTAAAT	CCATTACGTTTGCCTTGTTGTTAAAGCTTGCAAC
GTTTTAACTACTTATTATGAAATGTAAAT	AGCTGTAGCACCTTTCTGCAATCTTTCAGCCTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAAGTAAATGCCGTAGAAACGTCCTCACAACCACA
GTTTTAACTACTTATTATGAAATGTAAAT	ACAAGTGGCTTAATATAAAACGTTGGTGCTGTGGG
GTTTTAACTACTTATTATGAAATGTAAAT	TGATAACCGTCAAATAAGTCAGTGTCAACTTCGTC
GTTTTAACTACTTATTATGAAATGTAAAT	GTTGTTTTTTATGTTTAGCATCCATAGTCGTAAGG
GTTTTAACTACTTATTATGAAATGTAAAT	TTCGAAAAGTCTGTTTTGCCCTATGTCTAATCCTTT
GTTTTAACTACTTATTATGAAATGTAAAT	ACATTCGAAGTGGAGTGGCAACAAAAGCCTTATA
GTTTTAACTACTTATTATGAAATGTAAAT	AAGTTAATTATTGAATGCTATCCAGAAAGAATAGAAG
GTTTTAACTACTTATTATGAAATGTAAAT	GTGCTTAAAACGATGACAAAAGTAGGAATAACATCA
GTTTTAACTACTTATTATGAAATGTAAAT	TTGCTTATAGAAGCTTATTTGTCTATTATTACCAGC
GTTTTAACTACTTATTATGAAATGTAAAT	GTTGAAAAGCGCACCATTGTTTTAATTTTTTTAATT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTGTCGCATAAATTCTTTGATGTGGCGGACTGACG
GTTTTAACTACTTATTATGAAATGTAAAT	AACAGTATCATCACGTTGTTATTGCTGTCACCTGT
GTTTTAACTACTTATTATGAAATGTAAAT	ACGGGTACCAGCTTTGATTTGCTGTTTTCAATTATT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTATCACTCCTATGCTTTTCTTATTTCTGTAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	GCTTTTTTCAACAATTTTATCACCAGATGTCATTA
GTTTTAACTACTTATTATGAAATGTAAAT	TGAGCAGTGTCACCTGTTTCCGTATCTGCTTTTTTC
GTTTTAACTACTTATTATGAAATGTAAAT	ATAGATTAGTAGGGAAATAATATGTAATGGTTACTG
GTTTTAACTACTTATTATGAAATGTAAAT	AAGAAATCCGGGAAGTTTTGTTCTACAGAGCGAACGG
GTTTTAACTACTTATTATGAAATGTAAAT	CTTCTTAACCCTTTAACACAAGCGCAAGATGGCTGT
GTTTTAACTACTTATTATGAAATGTAAAT	TTAATAAATCCGATGGTGATGCCTATGTTATACGTC
GTTTTAACTACTTATTATGAAATGTAAAT	TAAAACATCGCTTCGTTATACAATGTCTTTTTATA
GTTTTAACTACTTATTATGAAATGTAAAT	TGTTATCTCCTGTGATGTAAAATAACCCTTCTATC
GTTTTAACTACTTATTATGAAATGTAAAT	CTTGTTAAGTCCCCACTTCCATTAAAATCGTAATTGT
GTTTTAACTACTTATTATGAAATGTAAAT	GTGTAATTCTTAATTCCGTATTGATTCGCTAGTTTT
GTTTTAACTACTTATTATGAAATGTAAAT	ACAATTAACACATTGTCAGTTCTGGTCTGGTATGTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TTGTTTATATGCACATAAATTTCGCGCATCCATAA
CGTTTTACTACTTATTATGAAATGTAAAT	TTTATACGTATGAGTCCGTCATATCGCATATTTA
GTTTTAACTACTTATTATGAAATGTAAAT	AAAGGTAAAAATATTCTTGCTGTGGCAGGTCCTGAT
GTTTTAACTACTTATTATGAAATGTAAAT	CTCTTCCACTTTTGCTGCTTTTTCCGCATCTGGTACAA
GTTTTAACTACTTATTATGAAATGTAAAT	ATTACTTAATTCTAGTTACGTTGCTGCGTTTACTTCT
GTTTTAACTACTTATTATGAAATGTAAAT	AAATTTTTTGTTGATAAGCATGCAGGAGCAAATAA
GTTTTAACTACTTATTATGAAATGTAAAT	CAGTGATTATGCTAAGACCTACACAATCGTTATCACT
GTTTTAACTACTTATTATGAAATGTAAAT	AGAGAAATCTCAAGAGCCAGCCAAGCAAGAGACATC
GTTTTAACTACTTATTATGAAATGTAAAT	GGCTTTCTGGAATTGTTTCGCTGACATCCCTGCCAG
GTTTTAACTACTTATTATGAAATGTAAAT	CAAAACAGAGAACGCGTGTTCATTATCGGACATCTTA
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTGAAATATGAGGACTTAGAAAATGAAAAAAAT
GTTTTAACTACTTATTATGAAATGTAAAT

>CP025560|2|2|548544-551810|CRISPRCasFinder
GTTTTAACTACTTATTATGAAATGTAAAT	CCATCCACGTGGACGGGACTTCTTTTACATCAAT
GTTTTAACTACTTATTATGAAATGTAAAT	TCAGCAAACCAATCCATTCAAGACGCCTTTGTGTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TAGTATCTCACTTCAAAACTATCTGTGTCACTATT
GTTTTAACTACTTATTATGAAATGTAAAT	CAAGAAGCACGTAAGATGTTTGTAGCACCAGACAAC
GTTTTAACTACTTATTATGAAATGTAAAT	CAAAAAGAAGTCGTATCTGAAAATAGCAAAGCACCTCA
GTTTTAACTACTTATTATGAAATGTAAAT	GACACTCATTTTTGCTGCTTGCTTACTAGTGACCTTT
GTTTTAACTACTTATTATGAAATGTAAAT	ACTGATAACCCTAATTTTGTAGCAATTACTGAAAGT
GTTTTAACTACTTATTATGAAATGTAAAT	CCTGAAATGGGGGCTTTTTTGTGATGAAAAACAC
GTTTTAACTACTTATTATGAAATGTAAAT	TGGTATAAATCTAAAAATACACAAGTTGTAAATGT
GTTTTAACTACTTATTATGAAATGTAAAT	TTACCACCAAAGTCCCTACACTCAATACCACCAAA
GTTTTAACTACTTATTATGAAATGTAAAT	CTAAAAAAGATTGGCAGAATGGAAATGTGTATGTGT
GTTTTAACTACTTATTATGAAATGTAAAT	CCATTACGTTTGCCTTGTTGTTAAAGCTTGCAAC
GTTTTAACTACTTATTATGAAATGTAAAT	AGCTGTAGCACCTTTCTGCAATCTTTCAGCCTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAAGTAAATGCCGTAGAAACGTCCTCACAACCACA
GTTTTAACTACTTATTATGAAATGTAAAT	ACAAGTGGCTTAATATAAAACGTTGGTGCTGTGGG
GTTTTAACTACTTATTATGAAATGTAAAT	TGATAACCGTCAAATAAGTCAGTGTCAACTTCGTC
GTTTTAACTACTTATTATGAAATGTAAAT	GTTGTTTTTTATGTTTAGCATCCATAGTCGTAAGG
GTTTTAACTACTTATTATGAAATGTAAAT	TTCGAAAAGTCTGTTTTGCCCTATGTCTAATCCTTT
GTTTTAACTACTTATTATGAAATGTAAAT	ACATTCGAAGTGGAGTGGCAACAAAAGCCTTATA
GTTTTAACTACTTATTATGAAATGTAAAT	AAGTTAATTATTGAATGCTATCCAGAAAGAATAGAAG
GTTTTAACTACTTATTATGAAATGTAAAT	GTGCTTAAAACGATGACAAAAGTAGGAATAACATCA
GTTTTAACTACTTATTATGAAATGTAAAT	TTGCTTATAGAAGCTTATTTGTCTATTATTACCAGC
GTTTTAACTACTTATTATGAAATGTAAAT	GTTGAAAAGCGCACCATTGTTTTAATTTTTTTAATT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTGTCGCATAAATTCTTTGATGTGGCGGACTGACG
GTTTTAACTACTTATTATGAAATGTAAAT	AACAGTATCATCACGTTGTTATTGCTGTCACCTGT
GTTTTAACTACTTATTATGAAATGTAAAT	ACGGGTACCAGCTTTGATTTGCTGTTTTCAATTATT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTATCACTCCTATGCTTTTCTTATTTCTGTAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	GCTTTTTTCAACAATTTTATCACCAGATGTCATTA
GTTTTAACTACTTATTATGAAATGTAAAT	TGAGCAGTGTCACCTGTTTCCGTATCTGCTTTTTTC
GTTTTAACTACTTATTATGAAATGTAAAT	ATAGATTAGTAGGGAAATAATATGTAATGGTTACTG
GTTTTAACTACTTATTATGAAATGTAAAT	AAGAAATCCGGGAAGTTTTGTTCTACAGAGCGAACGG
GTTTTAACTACTTATTATGAAATGTAAAT	CTTCTTAACCCTTTAACACAAGCGCAAGATGGCTGT
GTTTTAACTACTTATTATGAAATGTAAAT	TTAATAAATCCGATGGTGATGCCTATGTTATACGTC
GTTTTAACTACTTATTATGAAATGTAAAT	TAAAACATCGCTTCGTTATACAATGTCTTTTTATA
GTTTTAACTACTTATTATGAAATGTAAAT	TGTTATCTCCTGTGATGTAAAATAACCCTTCTATC
GTTTTAACTACTTATTATGAAATGTAAAT	CTTGTTAAGTCCCCACTTCCATTAAAATCGTAATTGT
GTTTTAACTACTTATTATGAAATGTAAAT	GTGTAATTCTTAATTCCGTATTGATTCGCTAGTTTT
GTTTTAACTACTTATTATGAAATGTAAAT	ACAATTAACACATTGTCAGTTCTGGTCTGGTATGTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TTGTTTATATGCACATAAATTTCGCGCATCCATAA
CGTTTTACTACTTATTATGAAATGTAAAT	TTTATACGTATGAGTCCGTCATATCGCATATTTA
GTTTTAACTACTTATTATGAAATGTAAAT	AAAGGTAAAAATATTCTTGCTGTGGCAGGTCCTGAT
GTTTTAACTACTTATTATGAAATGTAAAT	CTCTTCCACTTTTGCTGCTTTTTCCGCATCTGGTACAA
GTTTTAACTACTTATTATGAAATGTAAAT	ATTACTTAATTCTAGTTACGTTGCTGCGTTTACTTCT
GTTTTAACTACTTATTATGAAATGTAAAT	AAATTTTTTGTTGATAAGCATGCAGGAGCAAATAA
GTTTTAACTACTTATTATGAAATGTAAAT	CAGTGATTATGCTAAGACCTACACAATCGTTATCACT
GTTTTAACTACTTATTATGAAATGTAAAT	AGAGAAATCTCAAGAGCCAGCCAAGCAAGAGACATC
GTTTTAACTACTTATTATGAAATGTAAAT	GGCTTTCTGGAATTGTTTCGCTGACATCCCTGCCAG
GTTTTAACTACTTATTATGAAATGTAAAT	CAAAACAGAGAACGCGTGTTCATTATCGGACATCTTA
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTGAAATATGAGGACTTAGAAAATGAAAAAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAAAACTATGCAATTAGCAAAGTGATTTTATGTAATT
GTTTTAACTACTTATTATGAAATCATAAA

>CP025560|2|1|548544-551810|CRT
GTTTTAACTACTTATTATGAAATGTAAAT	CCATCCACGTGGACGGGACTTCTTTTACATCAAT
GTTTTAACTACTTATTATGAAATGTAAAT	TCAGCAAACCAATCCATTCAAGACGCCTTTGTGTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TAGTATCTCACTTCAAAACTATCTGTGTCACTATT
GTTTTAACTACTTATTATGAAATGTAAAT	CAAGAAGCACGTAAGATGTTTGTAGCACCAGACAAC
GTTTTAACTACTTATTATGAAATGTAAAT	CAAAAAGAAGTCGTATCTGAAAATAGCAAAGCACCTCA
GTTTTAACTACTTATTATGAAATGTAAAT	GACACTCATTTTTGCTGCTTGCTTACTAGTGACCTTT
GTTTTAACTACTTATTATGAAATGTAAAT	ACTGATAACCCTAATTTTGTAGCAATTACTGAAAGT
GTTTTAACTACTTATTATGAAATGTAAAT	CCTGAAATGGGGGCTTTTTTGTGATGAAAAACAC
GTTTTAACTACTTATTATGAAATGTAAAT	TGGTATAAATCTAAAAATACACAAGTTGTAAATGT
GTTTTAACTACTTATTATGAAATGTAAAT	TTACCACCAAAGTCCCTACACTCAATACCACCAAA
GTTTTAACTACTTATTATGAAATGTAAAT	CTAAAAAAGATTGGCAGAATGGAAATGTGTATGTGT
GTTTTAACTACTTATTATGAAATGTAAAT	CCATTACGTTTGCCTTGTTGTTAAAGCTTGCAAC
GTTTTAACTACTTATTATGAAATGTAAAT	AGCTGTAGCACCTTTCTGCAATCTTTCAGCCTCAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAAGTAAATGCCGTAGAAACGTCCTCACAACCACA
GTTTTAACTACTTATTATGAAATGTAAAT	ACAAGTGGCTTAATATAAAACGTTGGTGCTGTGGG
GTTTTAACTACTTATTATGAAATGTAAAT	TGATAACCGTCAAATAAGTCAGTGTCAACTTCGTC
GTTTTAACTACTTATTATGAAATGTAAAT	GTTGTTTTTTATGTTTAGCATCCATAGTCGTAAGG
GTTTTAACTACTTATTATGAAATGTAAAT	TTCGAAAAGTCTGTTTTGCCCTATGTCTAATCCTTT
GTTTTAACTACTTATTATGAAATGTAAAT	ACATTCGAAGTGGAGTGGCAACAAAAGCCTTATA
GTTTTAACTACTTATTATGAAATGTAAAT	AAGTTAATTATTGAATGCTATCCAGAAAGAATAGAAG
GTTTTAACTACTTATTATGAAATGTAAAT	GTGCTTAAAACGATGACAAAAGTAGGAATAACATCA
GTTTTAACTACTTATTATGAAATGTAAAT	TTGCTTATAGAAGCTTATTTGTCTATTATTACCAGC
GTTTTAACTACTTATTATGAAATGTAAAT	GTTGAAAAGCGCACCATTGTTTTAATTTTTTTAATT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTGTCGCATAAATTCTTTGATGTGGCGGACTGACG
GTTTTAACTACTTATTATGAAATGTAAAT	AACAGTATCATCACGTTGTTATTGCTGTCACCTGT
GTTTTAACTACTTATTATGAAATGTAAAT	ACGGGTACCAGCTTTGATTTGCTGTTTTCAATTATT
GTTTTAACTACTTATTATGAAATGTAAAT	TTTATCACTCCTATGCTTTTCTTATTTCTGTAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	GCTTTTTTCAACAATTTTATCACCAGATGTCATTA
GTTTTAACTACTTATTATGAAATGTAAAT	TGAGCAGTGTCACCTGTTTCCGTATCTGCTTTTTTC
GTTTTAACTACTTATTATGAAATGTAAAT	ATAGATTAGTAGGGAAATAATATGTAATGGTTACTG
GTTTTAACTACTTATTATGAAATGTAAAT	AAGAAATCCGGGAAGTTTTGTTCTACAGAGCGAACGG
GTTTTAACTACTTATTATGAAATGTAAAT	CTTCTTAACCCTTTAACACAAGCGCAAGATGGCTGT
GTTTTAACTACTTATTATGAAATGTAAAT	TTAATAAATCCGATGGTGATGCCTATGTTATACGTC
GTTTTAACTACTTATTATGAAATGTAAAT	TAAAACATCGCTTCGTTATACAATGTCTTTTTATA
GTTTTAACTACTTATTATGAAATGTAAAT	TGTTATCTCCTGTGATGTAAAATAACCCTTCTATC
GTTTTAACTACTTATTATGAAATGTAAAT	CTTGTTAAGTCCCCACTTCCATTAAAATCGTAATTGT
GTTTTAACTACTTATTATGAAATGTAAAT	GTGTAATTCTTAATTCCGTATTGATTCGCTAGTTTT
GTTTTAACTACTTATTATGAAATGTAAAT	ACAATTAACACATTGTCAGTTCTGGTCTGGTATGTTT
GTTTTAACTACTTATTATGAAATGTAAAT	TTGTTTATATGCACATAAATTTCGCGCATCCATAA
CGTTTTACTACTTATTATGAAATGTAAAT	TTTATACGTATGAGTCCGTCATATCGCATATTTA
GTTTTAACTACTTATTATGAAATGTAAAT	AAAGGTAAAAATATTCTTGCTGTGGCAGGTCCTGAT
GTTTTAACTACTTATTATGAAATGTAAAT	CTCTTCCACTTTTGCTGCTTTTTCCGCATCTGGTACAA
GTTTTAACTACTTATTATGAAATGTAAAT	ATTACTTAATTCTAGTTACGTTGCTGCGTTTACTTCT
GTTTTAACTACTTATTATGAAATGTAAAT	AAATTTTTTGTTGATAAGCATGCAGGAGCAAATAA
GTTTTAACTACTTATTATGAAATGTAAAT	CAGTGATTATGCTAAGACCTACACAATCGTTATCACT
GTTTTAACTACTTATTATGAAATGTAAAT	AGAGAAATCTCAAGAGCCAGCCAAGCAAGAGACATC
GTTTTAACTACTTATTATGAAATGTAAAT	GGCTTTCTGGAATTGTTTCGCTGACATCCCTGCCAG
GTTTTAACTACTTATTATGAAATGTAAAT	CAAAACAGAGAACGCGTGTTCATTATCGGACATCTTA
GTTTTAACTACTTATTATGAAATGTAAAT	TTTTGAAATATGAGGACTTAGAAAATGAAAAAAAT
GTTTTAACTACTTATTATGAAATGTAAAT	AAAAACTATGCAATTAGCAAAGTGATTTTATGTAATT
GTTTTAACTACTTATTATGAAATCATAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP025560.1\|AVU88930.1\|557357_557801_+\|hypothetical-protein	unknown	unknown	unknown
CP025560.1\|AVU88916.1\|537519_538950_-\|capsule-biosynthesis-protein-CapA	unknown	unknown	gnl\|CDD\|225399
CP025560.1\|AVU88928.1\|554980_556297_-\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|133432
CP025560.1\|AVU88917.1\|539070_539886_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
CP025560.1\|AVU88927.1\|553944_554949_+\|ROK-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224851
CP025560.1\|AVU88932.1\|559763_561095_+\|DUF1254-domain-containing-protein	unknown	unknown	gnl\|CDD\|227659
CP025560.1\|AVU88921.1\|543501_544284_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|273860
CP025560.1\|AVU88924.1\|548067_548346_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
CP025560.1\|AVU88925.1\|551881_552250_-\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|226282
CP025560.1\|AVU88919.1\|540976_542665_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09754_cas8b2_CAS-I-B	gnl\|CDD\|187884
CP025560.1\|AVU88934.1\|562109_563585_+\|hypothetical-protein	unknown	unknown	unknown
CP025560.1\|AVU88923.1\|546572_547061_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
CP025560.1\|AVU91330.1\|547073_548063_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
CP025560.1\|AVU88922.1\|544351_546559_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
CP025560.1\|AVU88931.1\|557846_559508_-\|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl\|CDD\|223732
CP025560.1\|AVU88933.1\|561139_561880_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133381
CP025560.1\|AVU88920.1\|542654_543524_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|274215
CP025560.1\|AVU88929.1\|556499_557252_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
CP025560.1\|AVU88926.1\|552397_553813_+\|lincomycin-resistance-protein-LmrB	unknown	unknown	gnl\|CDD\|129794
CP025560.1\|AVU88918.1\|540238_540961_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|273848

Protein	Function_ID	Function_description	E-value
CP025560.1\|AVU88916.1\|537519_538950_-\|capsule-biosynthesis-protein-CapA	gnl\|CDD\|225399	COG2843, PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) [Cell envelope biogenesis, outer membrane].	3.18655e-101
CP025560.1\|AVU88928.1\|554980_556297_-\|6-phospho-beta-glucosidase	gnl\|CDD\|133432	cd05296, GH4_P_beta_glucosidase, Glycoside Hydrolases Family 4; Phospho-beta-glucosidase. Some bacteria simultaneously translocate and phosphorylate disaccharides via the phosphoenolpyruvate-dependent phosphotransferase system (PEP-PTS). After translocation, these phospho-disaccharides may be hydrolyzed by the GH4 glycoside hydrolases such as the phospho-beta-glucosidases. Other organisms (such as archaea and Thermotoga maritima ) lack the PEP-PTS system, but have several enzymes normally associated with the PEP-PTS operon. The 6-phospho-beta-glucosidase from Thermotoga maritima hydrolylzes cellobiose 6-phosphate (6P) into glucose-6P and glucose, in an NAD+ and Mn2+ dependent fashion. The Escherichia coli 6-phospho-beta-glucosidase (also called celF) hydrolyzes a variety of phospho-beta-glucosides including cellobiose-6P, salicin-6P, arbutin-6P, and gentobiose-6P. Phospho-beta-glucosidases are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0
CP025560.1\|AVU88917.1\|539070_539886_-\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	5.01016e-50
CP025560.1\|AVU88927.1\|553944_554949_+\|ROK-family-transcriptional-regulator	gnl\|CDD\|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	1.02242e-20
CP025560.1\|AVU88932.1\|559763_561095_+\|DUF1254-domain-containing-protein	gnl\|CDD\|227659	COG5361, COG5361, Uncharacterized conserved protein [Function unknown].	5.15204e-73
CP025560.1\|AVU88921.1\|543501_544284_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	1.37797e-23
CP025560.1\|AVU88924.1\|548067_548346_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.1393e-30
CP025560.1\|AVU88925.1\|551881_552250_-\|DUF1304-domain-containing-protein	gnl\|CDD\|226282	COG3759, COG3759, Predicted membrane protein [Function unknown].	1.71019e-41
CP025560.1\|AVU88919.1\|540976_542665_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187884	cd09754, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	6.40364e-26
CP025560.1\|AVU88923.1\|546572_547061_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.69311e-59
CP025560.1\|AVU91330.1\|547073_548063_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	1.03751e-163
CP025560.1\|AVU88922.1\|544351_546559_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.50319e-61
CP025560.1\|AVU88931.1\|557846_559508_-\|SulP-family-inorganic-anion-transporter	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	7.81415e-148
CP025560.1\|AVU88933.1\|561139_561880_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133381	cd01106, HTH_TipAL-Mta, Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA. Helix-turn-helix (HTH) TipAL, Mta, and SkgA transcription regulators, and related proteins, N-terminal domain. TipAL regulates resistance to and activation by numerous cyclic thiopeptide antibiotics, such as thiostrepton. Mta is a global transcriptional regulator; the N-terminal DNA-binding domain of Mta interacts directly with the promoters of mta, bmr, blt, and ydfK, and induces transcription of these multidrug-efflux transport genes. SkgA has been shown to control stationary-phase expression of catalase-peroxidase in Caulobacter crescentus. These proteins are comprised of distinct domains that harbor an N-terminal active (DNA-binding) site and a regulatory (effector-binding) site. The conserved N-terminal domain of these transcription regulators contains winged HTH motifs that mediate DNA binding. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. Unique to this family, is a TipAL-like, lineage specific Bacilli subgroup, which has five conserved cysteines in the C-terminus of the protein.	2.56491e-51
CP025560.1\|AVU88920.1\|542654_543524_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	1.33672e-55
CP025560.1\|AVU88929.1\|556499_557252_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	5.24308e-64
CP025560.1\|AVU88926.1\|552397_553813_+\|lincomycin-resistance-protein-LmrB	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	3.97112e-80
CP025560.1\|AVU88918.1\|540238_540961_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|273848	TIGR01877, CRISPR-associated_endoribonuclease_Cas6_1, CRISPR-associated endoribonuclease Cas6. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This broadly distributed, highly divergent Cas family is now characterized as an endoribonuclease that generates guide RNAs for host defense against phage and other invaders. The family contains a C-terminal motif GXGXXXXXGXG, where the each X between two Gly is hydrophobic and the spacer XXXXX contains (usually) one Arg or Lys. The seed alignment for the current version of this model has gappy columns removed. Members of this protein family are found associated with several different CRISPR/cas system subtypes, and consequently we designate this family Cas6.	5.90561e-33

>CP025560.1|AVU88924.1|548067_548346_+|CRISPR-associated-endonuclease-Cas2
MYVILIYDISIENGGAKVWRNVFKICKKYLTHVQKSVFEGEITPALLVKLRMELDKYIRDDQDSVIVFSSRQQRWLEKEFWGLTDEKTSNFF
>CP025560.1|AVU91330.1|547073_548063_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MESYYLFSDGELKRKDNVIRLTAPDGRFKDLKVELTRDIFLFGEVTMNTKGLNYIGQLGIPVHIFNYYGFYSGSYYPRETNVSGQLLISQVEHYTDTEKRQLIACQFIEAASFNLLRNLKYYKQRGKDVSNEIDEIKFLRKSICKMNDIPSLMGIEGNIRKVYYEAWQKIINQKIDFEKRVKRPPDNMVNTLISYVNSLVYSSCLTEIYKTQLNPVISYLHSAGERRFSLCLDVAEIFKPLIADRIIFSLLNKNIITEDDFEKEANFCYMKKAARQKVLQAYDLRMKETIKHRDLGRNVSYRHLIRLECYKLVKHLMNDKEYEAFKIWW
>CP025560.1|AVU88923.1|546572_547061_+|CRISPR-associated-protein-Cas4
MRISGTHVYYYFVCKRKLWCFSKEIRMEHLDENVQLGKLLDESSYNREKGQVMIDETVNIDFIKDWKVLHEVKKSKAIEEAGIWQLKYYMYFLKQKGIIIEKGVVDYPKLRQRETIFLTTEDERKIEKILVDIEITTSSLKPPTIIDKPLCKKCAYYEYCYI
>CP025560.1|AVU88922.1|544351_546559_+|CRISPR-associated-helicase/endonuclease-Cas3
MHKYLAKSNPEETIQEHTDNLLKNYQRLKKLYPAVEIDWYLLELVCLLHDLGKMNLLFQTKLGNASGKGKEIPHGYLSVAFVPDSKLEEMGYSEDEIKVVYQAIARHHERKYDFSDSEWKKEIIKLEEQWAGFIYSQLGGNAEYSSEVEMLYFYPGSRIFEGNSAADAETFKKYVLLKGLLNRIDFAASGGIDVELENDFLMDSMEVQLSHFKAENPEADWNALQKYMMQHQNENIVVIAETGMGKTEAGLLWLGNNKGFFTLPLRAAINAIYERITKNIVTTNQAERVGLLHSETYSQYLLHEGNAEMDIDEYYTRTRQMSLPITICTLDQLFDFVFRYAGFEHKLATLSYSKVIIDEIQMYSSDLLAYLILGLSYIDKFGGKFCIMTATLPGIVTDLLLENGVDFVQPEDKFVSSRIRHSMEMVHTEIESEFIKPFFNNNRILVICNTISKAKKIYSELKEHFQGEEIHLIHSQFIKKDRSAKEDAIFKDGQKDSTKKCIWVATQVVEASLDIDFDLLFTELSDVNGLFQRMGRCYRNRALDVDTNVYVFDGGAKVCSGIGTFIDKLIFENSKTILNEHAGVLTEEKKMELVERVYSTEALRGSEFYNDLRKTINYVKAFDSYELDKADVRRRFRNINSVSVIPEEVWQDNVEEINSYFAILRKTSKEISTKEKMIARTNLAEFMVSIPDYLYKKGESVVREINRYESVIEFKCGYSDEIGIIMYEKQEDLFF
>CP025560.1|AVU88921.1|543501_544284_+|type-I-B-CRISPR-associated-protein-Cas5
MLIMKAIRVRLWQDLVNFKKPTSFQLKETYPLPPYSTVIGMVHTLCGFTSYHEMKISIQGKYFSKVNDLATRYEFKNGMTYDASRHQIKVDKYGVSRGVSTVELLVDLELLLHIIPEDPSLVPIIEKAFREPIEFPSLGRREDIATIQKVEVVDVEKRQPKKSTEISDGYNAYVPISLTENNSVHFKSHESSVGRDKLLGTRYLLTEKYERVNHGTEKAPKFFRKWRKKDVIYSSRIFVSKKDVFFFDEDDYLVFIEEEE
>CP025560.1|AVU88920.1|542654_543524_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MKNKGLAMTIIFQAESANYGESLGNISSLKKISRNNGDQYTYISRQAIRYNLMDQIGEKEAPVKAEGGGDKKVIQFLSEATITDFPELDFFGYLKTEKGSGGQKRSAKVRLSNAISLETFKGDLDFLTNKGQADKLNENMNIAQAEIHKSYYRYTITIDLDQIGIDGEIALDNKEKARRVKKLMDTVAFLYRDIRGRREDLKPLFVIGGVYDVKNPVFQNIVDVADNNIVIKNIKDLLTYEDIKENTRVGIIDGQFANSDEVKVELKAESVPAFFNDIKGKIDAYYESN
>CP025560.1|AVU88919.1|540976_542665_+|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MQTEIEVRADDWLINAGLTGFLNIVGKENVRIDGQAIYFTADLLEDFETKYFNFFIQEYKETLSWYKIVSYKETMEQFRIDKFASFDEVALGNLNKYMKDVVKFYLKKANYIKVFPLIDPSANVTKWLEKLNTINLTKKQKWDEVKADIIEEVKQTYTQLDLIIDFCASEKGLQYLGAKNLIYSVINKGWSGVSFLFKQTKFIDPYLDYKTTFVDPVLEYLDTDLSKAKYNCFNCNQPIKNLKLDLSFMNDVGFDTARKTAHVWDFNNDVATCPICRLIYSCVPAGFTYVYGEGMFVNDSYGVEELHRVNERMRNSILRFNKDGINSTNTYRALVESITMEHENNRRYELADIQLVRYENEHYRFNLLSKKMLHIVNDSKGILKSLIRCGYKEGNLNVNLYKEVIQHLMNNENLFTLIHKLIYYKQTSVNGLYYNMGHVSGILDINTKFLKEMEVMTNISQNQLWFVQNCGKEFKEGYVKKKSENKISGITYKLLNSLKVNDKDGFMDTLLNSYSYLSMPIPDVFIKMFSNNEAFKSVGYAFMLGVGGEKTKKEDGGNTDEK
>CP025560.1|AVU88918.1|540238_540961_+|CRISPR-associated-endoribonuclease-Cas6
MRLKINCDFDSKIIPKDFQSKVVSLFKAGIMKSSPERYENLFGGNKHKQYTFSVYLPKPQNKGAEIQLNEANCIINFSTGDAETGIIFYNALISLRGSKVLFGAGNHITVKNIQIVPEKKIIGKQTILRTLSPVVSRDHNRETFKNWFYSFEDEEFEPTLKRNMLPYLIDAFGEQARYDLEKLKITPISMKKVVVYCHEIHIESSVGIFELEAEAYLQKYLVENGIGTMTGSGFGMIEQF
>CP025560.1|AVU88917.1|539070_539886_-|histidine-phosphatase-family-protein
MKKNIFKLLMALCAVLLIAGCGNSTSADKKETKETKEDGTVTFYVVRHGKTMLNTTDRVQGWSDAVLTPAGEEVVKSAGKGLKDVDFSAAYSSDSGRAIQTANLILKESDKSADKEVQTDPRFREFNFGSYEGDLNENMWTDIAKSQGKTLEEWQKAGLSPKDFANSVAALDKTRVKEGENWPAEDYATIQARLKEGLTDVAKKESKNGDSNVLLVSHGLSIGALLDTIEPGYKLPAEGIKNASVTKITYKDGKFTIGDVNDLSYVEKGSK
>CP025560.1|AVU88916.1|537519_538950_-|capsule-biosynthesis-protein-CapA
MKKLTYVIITGLVLVFIAGAFWITNSTNQSDQKVTQTEPLKKTSPANVKTISSEAKKTLNSLASSGADKASISDLKQLIKELKSYPTEKNDSGVYLQNLTACLEAVKSYTTGKADEKALGKVYPAFLASEQKLSAIEKTNQYDWFYAAAATNQQGLKEKGVVTLTMVGDNSFGTYPETPEHLKFDNVFQKNNGNNTYVYKNCLPWFKSDDYTVINAESAFTNATKAENKKWRIKSDPAHVAFLPASGVEAANLANNHTMDYFQVGYDDTLKAFKENNIPVFNTDAPLETTIKGMKTVLLGYDCRMSQQSPAYLERIVKDVKKYKKEDTLVIVNMHWGVEYRETPTDYQTQFGHAILDAGADIIMGSHPHRLESVEKYKDKYIVYSMGDFAFGADPTLLSRMTSMFQLRFTKEDNKIVLKDISIVPTYENSDGSTTENNYQPLPVFGDDAKKIVDELNRISKPIEGGVTEYTYFDPF
>CP025560.1|AVU88925.1|551881_552250_-|DUF1304-domain-containing-protein
MAILAFILTFIVMIEHIYIMILEMFFANTKLAAKTFGVEKELLANKKVQTLFANQGLYNGFLAAGLVWGLFFAGAGMAEAVQIFFLSCVVVAALFGGATSSKGILVKQGLPAVLALVVVLLV
>CP025560.1|AVU88926.1|552397_553813_+|lincomycin-resistance-protein-LmrB
MQQEATGGQKIRPIPIIASFLMAGFIGLFSETALNMALSDLIQVFDISSATVQWLTTGYLLTLGILVPISGLLLQWFTTRGLFFTAVSFSIAGTLIAALSPTFAMLMIGRVVQAVGTALLLPLMFNTILLIFPEHKRGSAMGMIGLVIMFAPAVGPTISGLILENLTWNWIFWISLPFLIIALLFGMKFMQNVSVVTKPKIDILSIILSTLGFGGVVFAFSSAGESGWGSATVLVSIIVGGLALGLFVWRQLTMEKPLMDLKVFKYPMFTLGLILVFISFMMILSTMILLPLYLQNSLALAAFSAGLVLLPGGVLNGLMSPFTGRLFDAYGPRALVIPGFIVAVVALFFLTRIEVGTSALTIIVLHSVLMIGISMVMMPAQTNGLNQLPPKLYPDGTAIMNTLQQVSGAIGTAVAITIMSAGQKAYMETAQGVGPEQMVASLTAGIQNAFVFGLIMACIGLLCSLFIRKAK
>CP025560.1|AVU88927.1|553944_554949_+|ROK-family-transcriptional-regulator
MAIPRDLKELNKKNIKSILRQQGAMTKAKIAEVTGLSVVTVNKLIRDLVENEEILEQDNSVATGGRRAVSYEINPNFQQVLVISLQEKWKKITYSFSVYNLLGEPEFVEDMSGEDLDITALKRNTKDIICAFPKISCVVIGVPGIEIGGKLRAMDFPLLLNVQLRETLEAEVNLPVLVETDTNAAILGYKNRPVKEENIVGLYYPERFPPGAGLLMNGEILKGQNGLAGEIKHMPLQVDWDNFDFSVDEIKAHIRKMALLTMSFYDPETIVLYTNFYFGQKDFMEELKEELKQVYPYAVLPEIVLSRKFTTDYRIGLLAFGIDYLENNMTDWRI
>CP025560.1|AVU88928.1|554980_556297_-|6-phospho-beta-glucosidase
MTKGIKIATIGGGSSYTPELIEGFIKRQDELPVRELWLVDVEAGREKLEIVGNLAKRMVKKAGVNMEIHLTLDREEALKDADFVTTQLRVGLLDARVKDERIPNSYGVVGQETNGPGGMFKGLRTIPVILDICKDMERLCPDAWLINFANPAGMVTEAVLRYSNQKKVVGLCNGPIGIERNIAETLGVDVSEIYVEFVGLNHMVFAKTVYHNGKDVTKDVVFKMTEDEAGSSLKNINATGWDKTFLRTLNMIPIDYLRYYWQTKQQLEDQARAYAEHGTRAEVVKKVEAELFELYKQEELAEKPKQLEQRGGAYYSEAACNLINSIYNDKRDIQIVNTRNNGAILDIDPDSAVETNCVITRQGPIPLASGRLPIAINGIIQEIKTFERLTAEAAVTGDYDKALLAMTINPLTPSESVAREMLDELLEAHKEYLPNFFK
>CP025560.1|AVU88929.1|556499_557252_+|MurR/RpiR-family-transcriptional-regulator
MLFLDKNLELNDTELDIYNYIVANLDKVVYMRIRDLATEAHVSTTTILRFCRKFGCNGFSEFRVKLQLYLEEQKLAQIDMADETTYIDFLKRTAQPEFKAQIQNAVEILRDRELVLFAGVGSSGVIAEYGAIYFSSLFTLALHIEDPLNHPFYHLSSKLSDKICMIAISVEGENEDIIRYIHQLKAQNCKVISITNSAKSTIARLSDANIAYYINKEMYQEANITSQLPALYTIENIAREIRTQLDKEKM
>CP025560.1|AVU88930.1|557357_557801_+|hypothetical-protein
MYSNMKEKVVFTLIMCSLMILCMSSYNILLENGIGTDSLMIILKAFVPFLFIGFLLDFFVVGKIANRLHALLVSEDASKFKKIIMMQLLMVTFMCVLMSTLSLIVNQGEWSHLGILILRNYFVALFLQIFIVSPFVRLISPRIFALL
>CP025560.1|AVU88931.1|557846_559508_-|SulP-family-inorganic-anion-transporter
MFKHILLSLNGYKISYLRNDVISGVGVAALTIPVAMGYAQVAGLPPIYGLYASFLPVIAYVIFASSPQLIFGIDATASAITGSIILGTAGLAAGSKEAIALAPILAFFCAIFLVLFSVLKLGRFAKYISAPVLSGFISGLSVSIIMGQIPKIMGLKESGDSFFSSLGIIFGQFFQSNWISFAMGVVTVIIVITCKKVIPKIPMSLVVLVLGTMAAYFFKLDQYNVDIVGKIPVGFPSLALPDFGASSWALAIGGGLVCAIATFAGSLLPSESFAMRNKYTIDDNRELFAYGVSNFVAAFSGCSPASASVSRTAANEQFRGKTQMVSIVAATIIALIVAFLSGLLYYMPQPVLSGIVFAALVGIIDVDVLKGLFKVSRREATVWIVAALGTLLVGVIFGVLLGIFLSFINVVSRSMKSPIAILGVIEGRHGYFDLKRKPEAKPIPNVVIYRYSASLFFGNFNKFADGLKEAVQDDTKLVIFEASAIINIDTTATESMKDLLKWLDDKGIEYYFADLIDHLKTSFRKHDLGYLIDNGYTKKTVEDALDAYYAEHK
>CP025560.1|AVU88932.1|559763_561095_+|DUF1254-domain-containing-protein
MATQKNLVDLATKAYIYGFPFIFNTQQIERYVTVGIGGTKQVPFNNFTHASRLAEPSDKFVSVNNDTIYSNAPIDVSAGPVVLSVPDTSGRYYVLQFVDAWSNNFAYVGKRATGTSAGKFLLTPPNWNGDVPADMIEIKFPTNIGIIIGRLACDGEADLPTVRELQEQLKITPLNEGKEVDGFPEYDRSLGKELAFFEQLRVYMAQFPPAERDLVKQESFAPIGLMEKGVSPYSNPSEELKNALIEGAKAGLANIKKATTNFKSENGWGLTQHLFDYNADFFEIGTKKSLDWVIEDREEAYIIRAVSAITALWGNHGYEAVYLMTWTDTDGNALNGKNKYTLELNPIPPVDSFWSITMYDLPEYFLCENPINRYSIGDRTPGIQYNDDGGIAIVVSKDEPTDPKERANWLPAPDAEFRPMFRLYNPQQPLVDGSYHFPGFEKK
>CP025560.1|AVU88933.1|561139_561880_-|MerR-family-transcriptional-regulator
MQIKELAELTGVSVRTLHHYDKIGLLVPQKDDWNGYRIYSEKDVDKLQQILFFKELDFPLKKIQQILDDPLFDKNVALDMQRHLLIEKKQRIETMLATLDLTIKNEKGEITMTNKEKFTGFDFSSNPYEEEARKLWGDKVVEKANEKVNNMSEKEQLTLKESFDAEFRHLASVRKLTPESEEAQLEIDHFFHYLNDTHGNIYSLEAFASLGEMYVNDERFTKNIDQFGDGLSQFLQEAMTIYAKNK
>CP025560.1|AVU88934.1|562109_563585_+|hypothetical-protein
MIRKVKSISMWLWHHLTPQIFAVICVFIITIIALFMPPYIGMADNGDFFRIFSSNGLFVNNTNYDALQFGHFVKEFGIYQYFNENQVAIYSSQSIFIQMALLLNKLFWSTTVFDVRFLGGLQLALLLPAIYLLVAGLTAKMKGWPGYVVAALTVFIFADTAYTAYFNSFFSEGLILIMMLYISAGFLLLYQHKYNDYAMLGLIFVASLILITAKQQNAPIAVVIAVCGILVFFIRKNRAFRISAAATFLVIFLSGVVMYAFIPGEFVTINQYQTMTRGVLLDSENPEKSLEEMGMNSEFALLKGTNFYQKYKMIDLDSKLMEKEFYPNYNFVTVLSYYLENPKQFGKMLDLSAQNSFSIRPFEMGNFEKATGYKFKEKTHFFSAYSDVKEKFAPAKFTFLILWALVFLICYGVSAFKHFREKNIRGTLLFDLIVLLIGSGFAVILVTIVGDGEADLTKHNFLFNVCFDLTMLIGAASLLEVYLKKRGERNA

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Crispr_ID: CP025560_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025560_3

2582968-2583129

Orphan

Consensus_repeat	Method
TTTTTTTATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG	CRISPRCasFinder

1 spacers

WYL

The CRISPR arrays of CP025560_3

>merge|CP025560|3|2582968-2583129|CRISPRCasFinder
TTTTTTTATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGGGATTGGTTGAATTTAATAATTTGTGCTTCCCTTTTCGGGTTGTTCGTCCACTTTTTTTAATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG

>CP025560|3|3|2582968-2583129|CRISPRCasFinder
TTTTTTTATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG	GATTGGTTGAATTTAATAATTTGTGCTTCCCTTTTCGGGTTGTTCGTCCACT
TTTTTTAATGGAAACAACGCTCCACTTCGTTACGCCTTGTATTGGAGTTCTAGGG

Protein	Signature genes	Signature genes Name	Protein_function
CP025560.1\|AVU90906.1\|2590677_2591688_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|273675
CP025560.1\|AVU90899.1\|2583203_2583437_-\|preprotein-translocase-subunit-SecG	unknown	unknown	gnl\|CDD\|224233
CP025560.1\|AVU90898.1\|2582093_2582840_-\|carboxylesterase	unknown	unknown	gnl\|CDD\|224561
CP025560.1\|AVU90889.1\|2566570_2567467_-\|YafY-family-transcriptional-regulator	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
CP025560.1\|AVU90901.1\|2584462_2585182_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
CP025560.1\|AVU91374.1\|2585314_2585488_-\|hypothetical-protein	unknown	unknown	unknown
CP025560.1\|AVU90905.1\|2589352_2590543_-\|phosphoglycerate-kinase	unknown	unknown	gnl\|CDD\|234613
CP025560.1\|AVU90904.1\|2588551_2589307_-\|triose-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234589
CP025560.1\|AVU90902.1\|2585589_2586882_-\|enolase	unknown	unknown	gnl\|CDD\|234617
CP025560.1\|AVU90891.1\|2568256_2568676_-\|hypothetical-protein	unknown	unknown	unknown
CP025560.1\|AVU90896.1\|2579198_2579663_-\|SsrA-binding-protein	unknown	unknown	gnl\|CDD\|376590
CP025560.1\|AVU90903.1\|2587017_2588550_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	unknown	unknown	gnl\|CDD\|235463
CP025560.1\|AVU90900.1\|2583536_2584280_-\|carboxylesterase	unknown	unknown	gnl\|CDD\|224561
CP025560.1\|AVU90907.1\|2591719_2592766_-\|sugar-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225263
CP025560.1\|AVU90890.1\|2567511_2568081_-\|YdcF-family-protein	unknown	unknown	gnl\|CDD\|99750
CP025560.1\|AVU90892.1\|2569625_2573558_-\|DUF5110-domain-containing-protein	unknown	unknown	gnl\|CDD\|224418
CP025560.1\|AVU90897.1\|2579678_2582060_-\|ribonuclease-R	unknown	unknown	gnl\|CDD\|273947
CP025560.1\|AVU90895.1\|2578234_2579143_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|238045
CP025560.1\|AVU90894.1\|2574576_2577852_-\|glycosyl-hydrolase-family-31	unknown	unknown	gnl\|CDD\|224418
CP025560.1\|AVU90893.1\|2573572_2574517_-\|lmo2445-family-class-3-internalin	unknown	unknown	gnl\|CDD\|275380

Protein	Function_ID	Function_description	E-value
CP025560.1\|AVU90906.1\|2590677_2591688_-\|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl\|CDD\|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	0
CP025560.1\|AVU90899.1\|2583203_2583437_-\|preprotein-translocase-subunit-SecG	gnl\|CDD\|224233	COG1314, SecG, Preprotein translocase subunit SecG [Intracellular trafficking and secretion].	6.04836e-13
CP025560.1\|AVU90898.1\|2582093_2582840_-\|carboxylesterase	gnl\|CDD\|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	3.8639e-136
CP025560.1\|AVU90889.1\|2566570_2567467_-\|YafY-family-transcriptional-regulator	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	2.05686e-71
CP025560.1\|AVU90901.1\|2584462_2585182_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	4.31126e-18
CP025560.1\|AVU90905.1\|2589352_2590543_-\|phosphoglycerate-kinase	gnl\|CDD\|234613	PRK00073, pgk, phosphoglycerate kinase; Provisional.	0
CP025560.1\|AVU90904.1\|2588551_2589307_-\|triose-phosphate-isomerase	gnl\|CDD\|234589	PRK00042, tpiA, triosephosphate isomerase; Provisional.	7.345e-145
CP025560.1\|AVU90902.1\|2585589_2586882_-\|enolase	gnl\|CDD\|234617	PRK00077, eno, enolase; Provisional.	0
CP025560.1\|AVU90894.1\|2574576_2577852_-\|glycosyl-hydrolase-family-31	gnl\|CDD\|224418	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism].	0
CP025560.1\|AVU90896.1\|2579198_2579663_-\|SsrA-binding-protein	gnl\|CDD\|376590	pfam01668, SmpB, SmpB protein.	2.29197e-92
CP025560.1\|AVU90900.1\|2583536_2584280_-\|carboxylesterase	gnl\|CDD\|224561	COG1647, COG1647, Esterase/lipase [General function prediction only].	1.94931e-122
CP025560.1\|AVU90907.1\|2591719_2592766_-\|sugar-binding-transcriptional-regulator	gnl\|CDD\|225263	COG2390, DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription].	4.30628e-92
CP025560.1\|AVU90890.1\|2567511_2568081_-\|YdcF-family-protein	gnl\|CDD\|99750	cd06259, YdcF-like, YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been idenitified. The family also includes Escherichia coli sanA and Salmonella typhimurium sfiX, which are involved in vancomycin resistance; sfiX may also be involved in murein synthesis.	2.8348e-39
CP025560.1\|AVU90892.1\|2569625_2573558_-\|DUF5110-domain-containing-protein	gnl\|CDD\|224418	COG1501, COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism].	0
CP025560.1\|AVU90897.1\|2579678_2582060_-\|ribonuclease-R	gnl\|CDD\|273947	TIGR02063, Ribonuclease_R, ribonuclease R. This family consists of an exoribonuclease, ribonuclease R, also called VacB. It is one of the eight exoribonucleases reported in E. coli and is broadly distributed throughout the bacteria. In E. coli, double mutants of this protein and polynucleotide phosphorylase are not viable. Scoring between trusted and noise cutoffs to the model are shorter, divergent forms from the Chlamydiae, and divergent forms from the Campylobacterales (including Helicobacter pylori) and Leptospira interrogans. [Transcription, Degradation of RNA].	0
CP025560.1\|AVU90895.1\|2578234_2579143_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.81542e-08
CP025560.1\|AVU90903.1\|2587017_2588550_-\|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase	gnl\|CDD\|235463	PRK05434, PRK05434, 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.	0
CP025560.1\|AVU90893.1\|2573572_2574517_-\|lmo2445-family-class-3-internalin	gnl\|CDD\|275380	sd00033, LRR_RI, leucine-rich repeats, ribonuclease inhibitor (RI)-like subfamily. A leucine-rich repeat (LRR) is a structural protein motif of 20-30 amino acids that is unusually rich in the hydrophobic amino acid leucine. The conserved eleven-residue sequence motif (LxxLxLxxN/CxL) within the LRRs corresponds to the beta-strand and adjacent loop regions, whereas the remaining parts of the repeats are variable. LRRs fold together to form a solenoid protein domain, termed leucine-rich repeat domain. Leucine-rich repeats are usually involved in protein-protein interactions.	5.15574e-06

>CP025560.1|AVU90898.1|2582093_2582840_-|carboxylesterase
MKITPPQPFLFEKGKRAVLLLHGFTGSSADVRILGRFLQENNYTCYAPQYRGHGVSPDLLLKTGPNDWWEDVLEAYDHLKSLGYTEIAVAGLSLGGLFSLKLGFSRPLKGIIAMSTPTRMDSSSPIIQGFLDYVRNYKKLEGKTTEQIDAEMVAYKDAPMNTIAKLKDEISGVVAEIDMIYAPIMVVQGEKDDMVDVSGAQLIYDTVESTKKELHWFKESGHVITLDKERKEVNQAILTFLDSLDWQE
>CP025560.1|AVU90897.1|2579678_2582060_-|ribonuclease-R
MEQKQMEEKIMNLLTSAPDKTFALEDLEIEIALNNADDFKLMVKALVKLEDSGTIVRSRKNRYALPEKMDLVKGTFRAHERGFGFVLPEEKEMDDIFIPPNEVKDAMNGDLVFATITKRKGDNLAEGTIKKIVERKTTQIVGTYMEDLAGIPIVMPDDKRLFGEVEIDLEDGLKPVDGHKVIVELTEYATGNTRARGVVKSIIGHRNDPGVDILSIIHKHGISIGFPEEVMEQVSKAPDVVDDSDIGNRRDLRDQMIITIDGADAKDLDDAVTVKQLPNGNWKLGVHIADVTHYVTEGSPLDVEAQERGTSVYLVDRVIPMLPHKLSNGICSLNPQVDRFTMSCEMEIDQEGHVVNHEIFESIIKTTERMTYTDVNDILVEKDEALREKYAPIVPMLEAMQNLAEILRRKREKRGAIDFDFKEARVVVDEDGHPEAVVMRERSAGEHLIEEFMLAANETVAEHFHWMDVPFIYRIHEDPKEDKLARFFEFITNFGLIVKGTANDIHPAALQQVLEEVKGKPEEMVVSTVMLRSMQQAKYDTVSAGHFGLSTDFYTHFTSPIRRYPDLIVHRLIREYLINGDVRPETLEKRAEELPEIAEHSSKMERRAVEAERETDELKKTEFMVDKVGERFIGIISSVTNFGLFIELPTTIEGLVHVSAMKGDYFKFHQNQLAMIGERTGQIYRIGDEVEVEVTKVDVDAREIDFALRSEGKPGPVSDKQKRQREKPIDKTRNFKSSSKNNRNKRRTGKSEDVKPKTERKDDEWYTKPKKKKKKKPFYQGVAKESPKKKKRR
>CP025560.1|AVU90896.1|2579198_2579663_-|SsrA-binding-protein
MPKGDGKLVAQNKKARHDYAIEETFEAGIVLQGTEIKSVRNARVNLKDSYARIDKGEIFLHNMHISPYEQGNRYNHDPLRTRKLLLHKKQISRLIGETKESGYSIVPLKMYIKDGYAKVLIGVARGKKKYDKRQDLKQKEAKRDIERAFKERQQ
>CP025560.1|AVU90895.1|2578234_2579143_+|helix-turn-helix-domain-containing-protein
MQNIGDTLKFIRKSKNLTQQETCTNALSRSNYQKIENNKIMPSMDRFIQILLNFNMTLEEFEFVKRDFTPSPKENILYLYSKIITSSETDMILNVISKCDDYLENHNDIFISDIKASLEGILLAEKEHNFELAREKVAYIWDRLSEADELFWNDILILRNIFFIFENETAQHIVNRLISQLKKYRYLYPTLSIEISLHVNRATYLILDEEYELALHYIELSIKIAKHNHYYLQFCMAVAKKGIVLYKLDQKQQGKHFMQRALRVAKVLEEERILNGIKNEIDYFLHDELQDLSLNEFTKIDI
>CP025560.1|AVU90894.1|2574576_2577852_-|glycosyl-hydrolase-family-31
MKRRTRKCSLVFILGILIFSCLSGFGTNVFAMDGEYHSPYGDDDLYTVQPTERSPRDPKAGEDVILNITTWPIENGQDVWVEWTKNGVAQENVTAAYDYNSGNNTYWKADLGKFEKGDEITYTTKGSTNGGTAYESGPFTFYVTDWEYVQDVTSVVDNGDSITLNMTATAGDFSPKLYLSFEDLDTLRMELSPTGKETGHAGKSGYTVEDTAEKVTVTTEDLSIEIQKSPYRMEVHQADGTLLTSEYTTANSLGWLTDGKNVINQYQNNFMTPSDEAFYGFGERYDTINQRGKDVETYVYNEYQDQAQTERTYLAVPFFVSANKYGMYVNSDFHSQFQMASKVEDKYSFVLDNDGDMTNMLDYYVISGKDQNDIVNNYTDITGKTTLLPKWAFGLWMSANEWDRESDVSSALSNAKANDIPATGFVLEQWSDEETYYIWNNATYTAKKNGEAFSYDDFTFNGKWTDPKGMVDSVHDAGMNIVLWQVPVLKDDGTVYEQRDNDEEYMISQGYSADDGTGAPYRVPASQWFGNGILLDFTNKDAVDWWTSQREYLLTEVGIDGFKTDGGEMVWGRDTTFSNGEKGQEMRNRYPTDYVSSYFDFAKSINPEAVSFSRSGTSGAQKSGIYWSGDQTSTFDSFQASLKAGLSASTSGVSYWAWDMAGFTGDYPTAELYKRATAMAAFAPIMQFHSEKSDPSPSEERSPWNAVARTGDETILPTFQKYLYTRMNLLPYIYTAAKDTADNGKSMMRQMAMDYPEDVNARDLDEQYMFGDDLLVAPIVQEGQTEKEVYLPEGEWVDIWNGGVHPGGETISYYADVDTLPVFAKAGAIIPMNMTDGYQLGQNVGNDLKSYDNLTFRVYPSGDSEYSFYDDVNGGEMRDISVSEDFANEKVSVDLPAMADETTMQVFSTEPTSVTIDGADVAKADTLDAFNEATTGYYYDTVQNLTYVKAAAKDAKQAIVLNGVNHAPYEAEFGHLTNVTTASDHAGYTGTGFVAGFDAEKEAVEFDIDAVDGASDYTMEVRYSAGVEDATRTVYINGKKQQITLPKTANWDTWNTVEVPVTLQAGNNQVVFDFEADDTAGINFDHVVIKK
>CP025560.1|AVU90893.1|2573572_2574517_-|lmo2445-family-class-3-internalin
MKKIIGLTFVAICCILFAPTIKAQADTVPLPAPIIEAFPVEAIAEAIAGELDKDSVNDTITQADLDTMTAIPLPSLGLTGEDLSVLNNEVFTNAIELAIWSNNIGELPDLSEALPALENIEANGANITVFPDANYPNLTNVDLSQNNFGFNIPKFVGMEGLVSINMENAGLSGYIAEDIWMNMPNLDSLILNENHLISIPEDIFLSQQLGTHSFANQTATYPPTTIKQGENLKVFVPFIYQALDFIAPSNHDLIIIKDNGRTLYEPPYPTYDGSYMYTIETAGLQPGEHLLEISLGYNSGEYTGWYDFPVTITE
>CP025560.1|AVU90892.1|2569625_2573558_-|DUF5110-domain-containing-protein
MKKGMKQVCVSLAVVPLVWLNLGITQPLQVEVKAEETKKKETQKKANTETAKQLSKEEYAKLSAEEGLGNVLEATVTDNVITLKIDNGDEAEDDYLEISPLANNLLKVNLRPRNIENSPSTPMIDPNATFTAIGATIDLESDPMIISTDECTLEIDKEPARMTFKDKNGKTLLSESADGGIFDGGVRFKRGASDHVYGAYGISFSDGDLGMERDDTAADSNKTAQAGQQGNAGGPFMWSTAGYGLLVDSDGGYPYSVSDEEKLEFYYGDTIVEGRRYVKENVEMYLMSGEPEEIMSSYADVTGHTPMMPKWSLGFSNFEWGTNEAEFRENINTYRAKGIPIDSFAFDYDWKFYGDPTYGGDYGEFAWNTENFPSAKDTTLKSDMDALGVKMIGITKPRVVTNLEDGTATQQGKDADANGYWYPGQSAYEDYAFPVTVRSIDPYNADERNWWWSHSEDALDKGIVGWWNDETDKVSSNGADYWFGNFTTGFTSEAMYEGQRDYTNERVWQTGRTFYPGAQRYSTSTWSGDIGVQWKKGEVIDWANGMQEQPSTMLSTINLGQTKWGMDTGGFNANSGQVLNPDPELYSRWMEFSSLVPVFRTHGNQNQQRQPWFYGGAAEEVAKSSMTWRYSMIPYMYAYERQAYDSGVGLVQPLTFDNPTDENVVNLTDEWMFGDGLLAAPVLEEGAGSRDIYLPAGTWIDYNRGDVYEGNQTISYEVNDDDWTDVPMFVKQGAIMPMQQPQNYVGESAVKTIYLDTFASDKETSFTHYDDDGKSFDYEKDTYLKQKMTTSTSADTSTFTIGAKEGSYKADTENYIVKLHGNAAESVQVNGADSKVYDDLSALENADGSGYAVGSDVYGAVTYVKVPAQADADTVITTSGSASVVQTGTYEMETGSNFADTVADKPVAEKTYVDGYDKDGAGTTIYANVKDSGDYNVDLTYKNASADNQTLSIFVNGDYVKQTTLKPNTDWSVQSETLPLSAGKNSISYKVVTDTGDKADQVSLDKVNIGFTPTVAKVEAEEADLAGTLKVANDHWFYSGEGFVGGFGTAGDEIKFEVDVPADGEYVLNTRTANGTGMPQTLDLYTNGDYNSRVTFPSEGENWNIWSDTEKAVNLKAGTNKITFLRDGETTGNVNIDRILVSAEPINSPVQSEVNLLDNGGFERDAAATTNWVESHPDGQDKAYGVDSGSGVNPPESPAFGKQSAYFYLPGAYKQTLAQQIAVPVNNANYDVEAWVKVSNDDAAKAQMTVNNYDSSGGKTIDLVADDVWHYVTIKDVKVTTGNINTSFQMDSPGGTSIHIDNVRVMPSAE
>CP025560.1|AVU90891.1|2568256_2568676_-|hypothetical-protein
MYRLLSSAFFGIAVICLLFPWMSSGIDAATFELVYEPAYKLIWMQPIIIVGYLGFLCTIFIPKFQRGKNRIVPFIGILILVLGLLNLAVRPLFGFDSFNFSIIDAYVSELVEPAFLIAVSASILSLIMYAIYLKKSENL
>CP025560.1|AVU90890.1|2567511_2568081_-|YdcF-family-protein
MRSLRKIVIILIIIGFMYLLIVAAFMFSGSRTKPSENADTVLILGAKVKGNPAVPSLVLQERLDAAVAYLNEYPKAKVIVSGGQGADESATEASVMEEYLVNEGIARKRIETETKSKRTEENIKYSNAKFNLGKTVIVTSDYHMYRALMLAKRQGIDASGLPATSQTFAKYKGMMREVLSITYAWVFDH
>CP025560.1|AVU90889.1|2566570_2567467_-|YafY-family-transcriptional-regulator
MKLERILAILVMILERKVLASELAEKFEVSTRTIYRDMDTLLYAGFPVVALPGKNGGFTMLDTYKLATFTFSEAEKQILLEALEARSEFMLNDSQEILREKITLLQTEKPTSKHIFFDSATQHRQQIEAEVKRKIAYIQKAFTTNKQLKITYIAMSGAETTREISPQKLNLMDGSWYLEAYCHKRAAIRHFKLTRITSLKEIDKAIMEVEETEYQPAEMKRIVLEFPKNQLGKLLDYFLQEEMETGDDYVRVSFFYDLERNIIPFLLMFGSAVKILEPASLQKDYKSEVEKLYFNLNC
>CP025560.1|AVU90899.1|2583203_2583437_-|preprotein-translocase-subunit-SecG
MSTVLTVLLIIVSVLLITVIILQPGKSAGLSGAISGGAEQLFGKQKARGLELILHRTTIVLSVVFFAILIALAYFVQ
>CP025560.1|AVU90900.1|2583536_2584280_-|carboxylesterase
MSADRSFTLKAGNRAVLLLHGFAGTTEDVRELGEILAENGYTVHAPNFRGHGDEPAIFLKTTPEMWYEDAVAGYRQLEKDGYDEIAIVGVAMGGVFALKMAESFSPKAIVPLCANVNRKMRYIPIENYLTKQLKKQGIVEQEADQMLKNYLPEIDVMTEARATFYKNVARDIEKIHVPTMIGQGCQDEEIDADNANYIFKHIHTNDKQLCFYAGSGHDIVNDCEKDILEEDLIYFLDDLVWLEEKVV
>CP025560.1|AVU90901.1|2584462_2585182_-|alpha/beta-hydrolase
MIAEINGINLFYQIIGKGEPILLIHGNGQNHRSLKRMIDDLSTNHQVIAVDSRAHGKSEAGNTPLDFEVMALDMLSLLDYLKIDKYKVIGYSDGGIVALVMGKMQPNRQIASVVIGTNYHVNQIRFLPDLFCRVAYGAAFLLAPFSRFFERMKRQLALTIYHPHMSEADLQKISAPLLAVVGEYDLISSKDTRKMVHSVQHGEMVIVRNGLHYLPRQKPKQLLQLIHSFFSNLSAEIHK
>CP025560.1|AVU91374.1|2585314_2585488_-|hypothetical-protein
MLMKVKNSQASKVLETPKIKDAVVHEKSHPLAEKHSVQKKIINADMPQQQFHRRLMK
>CP025560.1|AVU90902.1|2585589_2586882_-|enolase
MSIITEVYAREVLDSRGNPTVEVEVYTEAGAFGRALVPSGASTGEYEAVELRDGDKARYLGKGVLKAVENVNDIIADKIIGFDVTDQIGIDKAMIELDGTPNKGKLGANAILGVSLAAARAAADELGVHLYEYLGGVNGKVLPVPMMNILNGGEHADNNVDVQEFMVMPVGAPNFKEALRMGAEILHALKAVLKGKGLNTGVGDEGGFAPNLKSNEEALETIMQAIKDAGYKPGEEVKLAMDAASSEFYNRETGKYELKGEGVTRTSEEMVTWYEEMITKYPIISIEDGLDENDWDGFKLLTERIGDRVQLVGDDLFVTNTTKLKEGIEKGIANSILIKVNQIGTLTETLDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPTRTDRVAKYNQLLRIEDNLADLAEYHGNETFYNLKK
>CP025560.1|AVU90903.1|2587017_2588550_-|2,3-bisphosphoglycerate-independent-phosphoglycerate-mutase
MSKSPVAIIILDGFGKRAETVGNAVAQANKPNFDRYWANFPHGELKAAGLDVGLPEGQMGNSEVGHTNIGAGRIVYQSLTRIDKAIEEGEFQENKALNNAFTHTKENNSDLHLFGLLSDGGVHSHINHLVALLETAKDKGVKNVYIHAFLDGRDVAPQSSLEYLETLEKAISDLNYGAIATVSGRFYAMDRDKRWERVEKAYKAIVSAEGEKFEDPIELVKASYANDKNDEFVVPAVITKDGKPVATVKDNDAVIFFNFRPDRAIQLSNAFTDKEWDHFDRGADHPKNIKFVTMTLYNPSVDAEVAFEPIEMKNVIGEVLSNEGLAQLRIAETEKYPHVTFFMNGGRNEEFPGESRILINSPKVETYDLQPEMSAYEVTDALVEDIKNDKHDAIILNFANPDMVGHSGMLEPTIKAIEAVDENLGRVVDLILEKGGSAIIFADHGNSETMSTPEGKPHTAHTTVPVPVIVTKKGVTLREGGRLADVAPTMLDLLGVKKPAEMTGESLIQK
>CP025560.1|AVU90904.1|2588551_2589307_-|triose-phosphate-isomerase
MRKPIIAGNWKMNKTAAKAGQFAEDVKNNVPSSDAVESVVAAPALFLQELVRLTEGTNLRVSAQNCYFEDEGAFTGEISPFALADLGVSYVIIGHSERREYFHETDEDINKKAHAIFKHGMTPIICCGETLDQREAGQTDTWVRGQIRAALAGLTEEQVIKSVIAYEPIWAIGTGKSSTSADANETCAVIRAEVADAVSQKAADAVRIQYGGSVKPENIADYLAESDIDGALVGGASLEPASFLALLEAVK
>CP025560.1|AVU90905.1|2589352_2590543_-|phosphoglycerate-kinase
MAKKVVTDLDLKDKKVLVRVDFNVPMKDGKITNDNRIVAALPTIEYILEQNGKAILFSHLGKVKTEEDKEGKSLRPVAVRLSELLGKEVKFVPTTRGPELEKAIDELKDGEVLLFENTRFEDIDGKKESKNDPELGKYWASLGDVFVNDAFGTAHRAHASNVGIASNLESAAGFLMEKEIKFIGGVVDNPARPLVAILGGAKVSDKIGVIENLLTKADKVLVGGGMTFTFMAAQGQEIGKSLLEADKVELAKGLLEKAGDKLVLPVDAVVSKEFSNDAPFHTVSADSIPADEMGLDIGQATIDLFTKELQGAKTVVWNGPMGVFELSNFAKGTIGVCEAIANLTDATTIIGGGDSAAAAMDLGFADKFTHISTGGGASLEYLEGKELPGVASISDK
>CP025560.1|AVU90906.1|2590677_2591688_-|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MTVKVGINGFGRIGRLAFRRIQNVEGIEVVAINDLTDAKMLAHLLKYDTTQGRFDGEVEVHDGFFKVNGKEVKVLANRNPEELPWGDLGVDIVLECTGFFTAQDKAELHIKAGAKKVVISAPATGDMKTIVYNVNHETLDGTETVISGASCTTNCLAPMAKVLEDKFGVVEGLMTTIHAYTGDQNTLDAPHPKGDFRRARAAAENIIPNTTGAAKAIGEVLPTLKGKLDGAAQRVPVPTGSLTELVTVLDKKVTVDEVNAAMEAASDPETFGYTSDQVVSSDIKGMTFGSLFDETQTKVLTVGDQQLVKTVAWYDNEMSYTAQLVRTLEYFAKIAK
>CP025560.1|AVU90907.1|2591719_2592766_-|sugar-binding-transcriptional-regulator
MSDLINIQKKLLPDVLMIMQKRYQILRSIYFSEPVGRRTLAGMLGMSERVLRGEVEFLKAQGLVEIASSGMTVTKEGLVVFRDLESVMNQLSGLHSMEEQLAKKLQIKKCLVVQGDSDDTPWVREEMGRVAVEQLDMALTEKRNIVAVMGGSTMATVAEMMTTDFAKGRELLFVPGRGGIGEDLDNQANTICDKMATKTNTKHRVLYVPEQLGEEAYRSLLKEPAIQEGLRLVQSANAIILGIGDALAMAKRRHTGEDVLEKIIHRKAVGEAFGYYFDEQGEVVHKVPTFGLQFEDLAQIPHIIAVAGGTSKAKAIKSYMKSAPKNTILITDEGAAKSLLKGSNTLLK

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Crispr_ID: CP025560_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

CP025560_4

2842956-2843066

Orphan

Consensus_repeat	Method
AGCGATGATTTAATCCTTCCCAGAACTTTCAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of CP025560_4

>merge|CP025560|4|2842956-2843066|CRISPRCasFinder
AGCGATGATTTAATCCTTCCCAGAACTTTCAAAATGTACTTTATTTTGATTTAGTTCTTCAATATAAATCTGAGCAAAGCGATGATTTAATCCTTCCCAGAAGTTTCAAAA

>CP025560|4|4|2842956-2843066|CRISPRCasFinder
AGCGATGATTTAATCCTTCCCAGAACTTTCAAAA	TGTACTTTATTTTGATTTAGTTCTTCAATATAAATCTGAGCAA
AGCGATGATTTAATCCTTCCCAGAAGTTTCAAAA

Protein	Signature genes	Signature genes Name	Protein_function
CP025560.1\|AVU91158.1\|2843835_2844057_-\|hypothetical-protein	unknown	unknown	unknown
CP025560.1\|AVU91148.1\|2836492_2836867_+\|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM	unknown	unknown	gnl\|CDD\|184702
CP025560.1\|AVU91155.1\|2841102_2842842_-\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|235505
CP025560.1\|AVU91160.1\|2845997_2846153_+\|hypothetical-protein	unknown	unknown	unknown
CP025560.1\|AVU91159.1\|2844191_2845556_-\|PTS-sugar-transporter-subunit-IIC	unknown	unknown	gnl\|CDD\|224372
CP025560.1\|AVU91149.1\|2836972_2837824_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
CP025560.1\|AVU91162.1\|2848063_2849578_-\|gluconate-kinase	unknown	unknown	gnl\|CDD\|212659
CP025560.1\|AVU91165.1\|2851748_2853488_-\|thiol-reductant-ABC-exporter-subunit-CydC	unknown	unknown	gnl\|CDD\|227320
CP025560.1\|AVU91147.1\|2835892_2836489_+\|dihydroxyacetone-kinase-subunit-L	unknown	unknown	gnl\|CDD\|274099
CP025560.1\|AVU91154.1\|2840755_2841073_-\|nucleoid-associated-protein,-YbaB/EbfC-family	unknown	unknown	gnl\|CDD\|234669
CP025560.1\|AVU91146.1\|2834881_2835871_+\|dihydroxyacetone-kinase-subunit-DhaK	unknown	unknown	gnl\|CDD\|237724
CP025560.1\|AVU91157.1\|2843650_2843833_-\|DUF3188-domain-containing-protein	unknown	unknown	gnl\|CDD\|371501
CP025560.1\|AVU91164.1\|2850674_2851607_-\|cell-surface-protein	unknown	unknown	gnl\|CDD\|273478
CP025560.1\|AVU91150.1\|2837942_2838782_+\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|319818
CP025560.1\|AVU91156.1\|2843168_2843633_-\|DUF3284-domain-containing-protein	unknown	unknown	gnl\|CDD\|378692
CP025560.1\|AVU91163.1\|2849693_2850632_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226309
CP025560.1\|AVU91151.1\|2838902_2839745_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|223729
CP025560.1\|AVU91152.1\|2839790_2840036_-\|DUF2508-domain-containing-protein	unknown	unknown	gnl\|CDD\|378478
CP025560.1\|AVU91153.1\|2840050_2840647_-\|recombination-protein-RecR	unknown	unknown	gnl\|CDD\|234616
CP025560.1\|AVU91161.1\|2846724_2847366_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
CP025560.1\|AVU91148.1\|2836492_2836867_+\|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM	gnl\|CDD\|184702	PRK14484, PRK14484, phosphotransferase mannnose-specific family component IIA; Provisional.	2.28713e-49
CP025560.1\|AVU91155.1\|2841102_2842842_-\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|235505	PRK05563, PRK05563, DNA polymerase III subunits gamma and tau; Validated.	0
CP025560.1\|AVU91159.1\|2844191_2845556_-\|PTS-sugar-transporter-subunit-IIC	gnl\|CDD\|224372	COG1455, CelB, Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism].	4.45629e-162
CP025560.1\|AVU91149.1\|2836972_2837824_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	3.97147e-62
CP025560.1\|AVU91162.1\|2848063_2849578_-\|gluconate-kinase	gnl\|CDD\|212659	cd07770, FGGY_GntK, Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases. This subfamily is composed of a group of gluconate kinases (GntK, also known as gluconokinase; EC 2.7.1.12) encoded by the gntK gene, which catalyzes the ATP-dependent phosphorylation of D-gluconate and produce 6-phospho-D-gluconate and ADP. The presence of Mg2+ might be required for catalytic activity. The prototypical member of this subfamily is GntK from Lactobacillus acidophilus. Unlike Escherichia coli GntK, which belongs to the superfamily of P-loop containing nucleoside triphosphate hydrolases, members in this subfamily are homologous to glycerol kinase, xylulose kinase, and rhamnulokinase from Escherichia coli. They have been classified as members of the FGGY family of carbohydrate kinases, which contain two large domains separated by a deep cleft that forms the active site. This model spans both the N-terminal domain, which adopts a ribonuclease H-like fold, and the structurally related C-terminal domain. Some uncharacterized homologous sequences are also included in this subfamily. The Lactobacillus gnt operon contains a single gntK gene. The gnt operons of some bacteria, such as Corynebacterium glutamicum, have two gntK genes. For example, the C. glutamicum gnt operon has both a gluconate kinase gntV gene (also known as gntK) and a second hypothetical gntK gene (also known as gntK2). Both gluconate kinases encoded by these genes belong to this family, however the protein encoded by C. glutamicum gntV is not included in this model as it is truncated in the C-terminal domain.	0
CP025560.1\|AVU91165.1\|2851748_2853488_-\|thiol-reductant-ABC-exporter-subunit-CydC	gnl\|CDD\|227320	COG4987, CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones].	0
CP025560.1\|AVU91147.1\|2835892_2836489_+\|dihydroxyacetone-kinase-subunit-L	gnl\|CDD\|274099	TIGR02365, dha_L_ycgS, dihydroxyacetone kinase, phosphoprotein-dependent, L subunit. Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.	3.29756e-82
CP025560.1\|AVU91154.1\|2840755_2841073_-\|nucleoid-associated-protein,-YbaB/EbfC-family	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	4.39574e-40
CP025560.1\|AVU91146.1\|2834881_2835871_+\|dihydroxyacetone-kinase-subunit-DhaK	gnl\|CDD\|237724	PRK14481, PRK14481, dihydroxyacetone kinase subunit DhaK; Provisional.	0
CP025560.1\|AVU91157.1\|2843650_2843833_-\|DUF3188-domain-containing-protein	gnl\|CDD\|371501	pfam11384, DUF3188, Protein of unknown function (DUF3188). This bacterial family of proteins has no known function.	1.21027e-11
CP025560.1\|AVU91164.1\|2850674_2851607_-\|cell-surface-protein	gnl\|CDD\|273478	TIGR01167, Zinc_metalloprotease_ZmpB, LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other].	1.15414e-05
CP025560.1\|AVU91150.1\|2837942_2838782_+\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|319818	cd07516, HAD_Pase, phosphatase, similar to Escherichia coli Cof and Thermotoga maritima TM0651; belongs to the haloacid dehalogenase-like superfamily. Escherichia coli Cof is involved in the hydrolysis of HMP-PP (4-amino-2-methyl-5-hydroxymethylpyrimidine pyrophosphate, an intermediate in thiamin biosynthesis), Cof also has phosphatase activity against the coenzymes pyridoxal phosphate (PLP) and FMN. Thermotoga maritima TM0651 acts as a phosphatase with a phosphorylated carbohydrate molecule as a possible substrate. Escherichia coli YbhA is also a member of this family and catalyzes the dephosphorylation of PLP, YbhA can also hydrolyze erythrose-4-phosphate and fructose-1,6-bis-phosphate. Members of this family belong to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	7.1326e-85
CP025560.1\|AVU91156.1\|2843168_2843633_-\|DUF3284-domain-containing-protein	gnl\|CDD\|378692	pfam11687, DUF3284, Domain of unknown function (DUF3284). This family of proteins with unknown function appears to be restricted to Firmicutes.	5.35099e-31
CP025560.1\|AVU91163.1\|2849693_2850632_-\|hypothetical-protein	gnl\|CDD\|226309	COG3786, COG3786, Uncharacterized protein conserved in bacteria [Function unknown].	3.04876e-98
CP025560.1\|AVU91151.1\|2838902_2839745_+\|aldo/keto-reductase	gnl\|CDD\|223729	COG0656, ARA1, Aldo/keto reductases, related to diketogulonate reductase [General function prediction only].	1.3196e-129
CP025560.1\|AVU91152.1\|2839790_2840036_-\|DUF2508-domain-containing-protein	gnl\|CDD\|378478	pfam10704, DUF2508, Protein of unknown function (DUF2508). This family is conserved in Firmicutes. Several members are annotated as being the protein YaaL. The function is not known.	2.68189e-15
CP025560.1\|AVU91153.1\|2840050_2840647_-\|recombination-protein-RecR	gnl\|CDD\|234616	PRK00076, recR, recombination protein RecR; Reviewed.	7.77001e-132

>CP025560.1|AVU91155.1|2841102_2842842_-|DNA-polymerase-III-subunit-gamma/tau
MAYQALYRVFRPQSFQDVVGQEHVTKTLKNAIVQNKTSHAYLFSGPRGTGKTSAAKIFAKAINCEHGHDGEPCNECEICKGTTDGSIPDVLEIDAASNNGVEEIRDIREKVKYAPTVAKYKVYIIDEVHMLSTGAFNALLKTLEEPPKHVIFILATTEPHKLPLTIISRVQRFDFKRITTQDIIGRLKFILEEEKIPYDEKALMIVARAAEGGMRDALSLLDQVISYGSEEVTVEDALEITGSVAQNLLTKLVSAAFDGDAAEAISTLTALLAEGKDPVRLVEDLLVFFRDVLLYQKAPNLEETMERALIDDDFVALAKRADSLKVYEFVKILNTAQQQMRFSNHPGIYVEVALVQLTQAGQSVAGGGNVPADAASESDISDLKRQMEQMHQEIQTLKKQIASGAGAAPADKPTQNRGGSKKAINNGKQFKAPIGKINHVLGEAKKENLQLIRGCWGELLSMLMASQAALLNDAEPVAASQDTFVLKFKHEIHCQMAMDNPNFVETITSSIARLTQVNYTFIGIPEDQWADVRENFLHSHGSDADAEDGANPEAKKPAEDPFVAEAAKLVGEDLLEIKD
>CP025560.1|AVU91154.1|2840755_2841073_-|nucleoid-associated-protein,-YbaB/EbfC-family
MRGMGNMQGMMKQMQKMQKEMAKAQADLEAQEFTGTAGGGMVTVKATGKRVITDVVINEEVVDAEDIEMLQDLVLAATNDVLKQIEDTTSQTMGKFTQGLNIPGM
>CP025560.1|AVU91153.1|2840050_2840647_-|recombination-protein-RecR
MHYPEPITKLIDSFMKLPGIGPKSAARLAFYVLDMKEDDVLDFAKALVDAKRNLSFCSVCGHITDKDPCYICADTSRDRSVICVVQESKDVIAMEKMRDFHGLYHVLHGTISPMDGIGPEDINIPDLLKRLQDDTIEEVILATNPNVEGEATAMYISRLLKPSGIKVTRIAHGLPVGGDLEYADEVTLSKAMEGRREV
>CP025560.1|AVU91152.1|2839790_2840036_-|DUF2508-domain-containing-protein
MESRSNKFGRKKNKKIGKLHKSYDAYLMELIEVTQENWHKQKVLMRKSFEYDPNLEYEEKKAEARYFYLFKEARTRQLKNK
>CP025560.1|AVU91151.1|2838902_2839745_+|aldo/keto-reductase
MTLSFSDTYRLNNGIEMPRHGFGVYKLTDEARMRTALETAVDVGYRLFDTASFYHNEKELGDFFASSGLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDKIDLYLVHWPKQDTFFDTWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFPNHLLHRYLEELHIVHQAWSPLGRGGVLQEQILIDLAEKHGKSPAQIVLRWHLQNNISIIPKSETPSRIRENAAIYDFELSEADMRQVERLNTGERVSHAPDVMYVRSEI
>CP025560.1|AVU91150.1|2837942_2838782_+|Cof-type-HAD-IIB-family-hydrolase
MTTQAIILDIDGTLLNDDKKISPETKKALITAQQNGVKLILASGRPTTGMHVYAEQLEMEKHHGLLVSYNGAKVVDCATNEELFNQALTVEEGKAVLEHMKQFKVKVMIDKEDYMYTNDVYDCYVPYRGEEINIIQYESRGGNFKLCEKDDLAAFLDYRLSKILTAGDPAYMQKNYQAMMAPFKDTLNCVFTADFYFEFTAQGIDKAKALDTVLTPMGIHAENIIAFGDGHNDITMVEYAGTGIAMQNAVAELKAAASSVTLSNNEDGIAHVLNSLIPS
>CP025560.1|AVU91149.1|2836972_2837824_+|MurR/RpiR-family-transcriptional-regulator
MNILIKIRELTNLTNSEKELANYILVNPKKTLQFKPKELAAAAFVSAATIYRLINKLGLNGIGELKIEIASSLRETNAEKDINYDYPILESDTPYQIMTNLNQIYKGTIDETLNNADPEELVKIGEKLINAKTIDVYAASANLFFAQNFKFQMQEIGVLVNVPEEDYIQSLSAANSDENHIAIVVSYGGRSRTLQRVVKILSENNVDIILITSMQDNPLVEFATHKIYMASAENHYNKVSSFSTRQSLLSIFDTLYSIYFNQNYEKNIQYKTTNYQKMNTELE
>CP025560.1|AVU91148.1|2836492_2836867_+|PTS-dependent-dihydroxyacetone-kinase-phosphotransferase-subunit-DhaM
MTKPYGVVIISHSKDVAKGVHDIIKEIAPDVSITHAGGTEDGRIGTSFDAVNEAIESNEADKVYTFYDLGSAKMNIETVEEISEKEIILFNAPILEGAYATAAQVQMDEKPEVIAANLKTIEIK
>CP025560.1|AVU91147.1|2835892_2836489_+|dihydroxyacetone-kinase-subunit-L
MTYDKDWALRWLNDFGERVQENKQLLSDLDQAIGDGDHGINMARGLGELKKAFTEKEPADLKDVFKTAGMTMVSKVGGASGPLYGTAFLNMSKAVDADTIDAVGLTKVIEAGLEGIEKRGKSHAGEKTMIDVWEPVVHALHQEDLTDDVVDAALQKTKDLKATKGRASYLGERSIGHLDPGAYSSALLFHAMLQTEVS
>CP025560.1|AVU91146.1|2834881_2835871_+|dihydroxyacetone-kinase-subunit-DhaK
MKKILNGTDQVVEQMVEGLVKSHADVVHRVEGTRVIARNDKRPGKVGLVSGGGSGHEPAHAGYVGRGMLSAAVCGDVFTSPTPDQIYEGIKAADQGAGVLLIVKNYTGDVMNFEMAADLADADDIKVEQIVVDDDIAVEDSTFTTGRRGVAGTVLVHKIIGAAAEAGASLDELKALGEKVIASVKTLGVALSPCTVPEVGHPGFELGDDEIELGIGIHGEPGFTREKIMPSASLAKQLYERISNESKLLAGDKVVVLVNGMGATPLMEQYVFANDVHELLKNAGVQVEKTLVGDYMTSLEMAGLSLTILKLEDEKWVDMLKLPVDTIAW
>CP025560.1|AVU91156.1|2843168_2843633_-|DUF3284-domain-containing-protein
MNVTQKLYISQKECFDTLVSSAIYDVKNATGKTLQVRKLEGYKYQRTMSNGALATTKIVKVQPNELYQFETSSRVNTHTTTYTIKSTSETTCEVTYNELIETEKALNKMNNIIVGFMFGFFRKKRVKNLLKSIELSVINESKQKQEKLAAKSEQ
>CP025560.1|AVU91157.1|2843650_2843833_-|DUF3188-domain-containing-protein
MKIVNALFLISIGLIIIMFSPSYGKDGMASVPLLVTGLAVVLIGCVFIVLKIRKDKKEKN
>CP025560.1|AVU91158.1|2843835_2844057_-|hypothetical-protein
MIILNCPMKRDYITELLETYDKDGVTFKKIDEKGMKLTFETNIEDEEKAAKIAKETIKATEIGSVLYFQVSVG
>CP025560.1|AVU91159.1|2844191_2845556_-|PTS-sugar-transporter-subunit-IIC
MNGLTAFLEKYFVPVAAKIGSQKHLVALRDAFISTMPITMAGSIAVLLNAFFRDFPTDWGWTGFVEAMQPLIDINGYVYNGTLAIVSIIFAFSLGYNLSKAYEVDRLAGGLVSLAAFVMNLTVTVSLDAVKAAIAASNANFDIATLPKEFAGIYGFFSLSQVNGTGLFTAMIFGFISTIIYAKLMRRNIIIKMPDSVPPAVSKAFAAIIPALVALYVVGIIDWAFFKITNMDVITWISKTIQEPLLSLSQGYGAVLLVTFLVQLLWFFGIHGPNVLAPVLESLWGTAQLQNISAAQEGAKLPFEWVRGSFDAYVWMGGSGGTLVLIIALLMFSKRADARTVAKLSLAPGIFNINEPIMFGLPIVLNTIYLIPFLIAPMVMVTIAYFATTLGIVGPVKIAVVWVMPPLLNSFLATGGDWMAPVISLINMVVAFLIWVPFVITANRVGVPEEEMKA
>CP025560.1|AVU91160.1|2845997_2846153_+|hypothetical-protein
MAVKRDMPEESKNSKVVKKEHFSIVFPDDIKEPATVEEKKKQDAEKKTDDN
>CP025560.1|AVU91161.1|2846724_2847366_-|hypothetical-protein
MQQLKSKKKWLPALIVAILIGIIAILAIMFGFFQRQEVFDKYEVAYEIDGKLYEVFPISATDIGVDKKSKDKNLYFRVNSYYNIDYLFRLAYKQYEINEPSTNKYYSGLIDYSVADNAYVTQKDVYITNNESYATYDFFDKNGKKIYSYNPEETSNDDYIVRIKPTILQGYEKSDIGSYDDYLNITALFKDKLGMDVNVRIDDDKEMVIFSIK
>CP025560.1|AVU91162.1|2848063_2849578_-|gluconate-kinase
MTSKPYIMGVDIGTSSTKAVLFNQRGEVIFRQATHYELITDETGKAEESPTEIFDAVLTSIQAVMKNINTEELAGISFSSAMHSLIMVGSNGELLTECITWADGRSSETLEKVKRDNYLFQLYEATGTPIHPMSPFAKICWLKEEKPTLFKRTEKFVDIKSYILYRLFGVWVMDESLASGTGLYNIMEHDWEFEAMEIVKLTPDFLPKVVPETYQLAGVKKEYAELMGIPENLPFIIGGSDGALANIGIQATGQNDVTITVGTSGAVRKLTDQFQIDSRGRTFCYGAGDGYFIAGGAVNNGGKVVEWGLQQFGSEAEISRRDFASFIAKIEEVPTGAAGLLFQPYLLGERAPFWTNDIRGGFVGLTINHTKAHFIRAILEGVAFNLAEVYEAVSAPDDIIYVTGGISAHDAWCKLLADILNREIRVPHTIEGSSLGAAIIGMRSLGILKDLNLKHTLPIKAVYHPSENVLKYAELRLIFKQVTTQLMSSYSQLNSWQKKFDINS
>CP025560.1|AVU91163.1|2849693_2850632_-|hypothetical-protein
MKKLLSGLIVVLMVSLLGHSFNAEAASYEKIIYDKAVNLKGVVNQSKRNDGINSKMYKTSSSVKYLGSAKKYDKKTLIITREGKTARAKWYYCKLGNTTIGWIDSRAFTNIGKPTIADAVPALWNSKKAIITTKPKSTTATTYFFQKNSAGNWYEVRHFTSHIGKWGFDPKFSEKSSGTPVGVYRTGIAFGQKGNPGTKLTFRAITNRSYWISNSNDKAYNTWQERNSSSSADEKMKIPQYKYGMEVKYNAKRVKGKGSAVFYHVDSPKYNYTLGCVAQSEANTKEVLKFADKNTLIVLGEESRIKTFYGIN
>CP025560.1|AVU91164.1|2850674_2851607_-|cell-surface-protein
MKKFHGLILTALVTCLIIPFSLAASAETNENGNNSTPTEEKTTDTTEEKTEPAEPTKDTTVTPPQKSKVQTTIDITDSQEVYSYEQNSKIDLKDFTATLTDYTDTKLTNYRLAANSKLSTAQTGIQEVTLLGDNEDGKTTAVKLNYLVKEKTAQLTITDMNFDLETKIFTGKTKPFASVYMSSPADENFGEGTTTADKDGYFYAEWATTPKQITAYAFDESGNYSEEVTYQVPAKKQNEAVVTAPDKVKKIETKNAVKSATTKPTDVTKVTKDDKTDLPSTGDKGTEWIFVVAGVIVILVAVLLLRKRKK
>CP025560.1|AVU91165.1|2851748_2853488_-|thiol-reductant-ABC-exporter-subunit-CydC
MRKSSWIIPYIKENRGLFLLVIFLGTLTFASAGALMFTSGHLISKSSLMPESIMAVYISTVGVRAFGIMRSVSRYVERLSSHSLVLRILEKMRVRLYRLLEPQALLLKSRYKTGDILGLLAGDIEHLQNFYLTTMLPAIVSLVLYAGVVIALGAFSIPFAALFVLLIGLLVLVLPWVSLLYARGKNAYLKQGRNSLYQKFTDAVFGISDWKFSGREKTFISNYEKDEADMLRTENKQFHFVNWRDFFSQLVVGFMVIVMVYWSTAESRDGAFSGTMIAAFVLAIMALAEAFVPVSSAISDKSLYQDSLARLDKIEDPALPTFEEETKEIERINTENVVLKAENLTFAYDEKSPEILNGFDFTLQQGEKVAIIGRSGTGKSTFLKLVQGALLPTAGKVTMNDVEVEKLRPQIPELTSMLNQKAHLFSTTVLNNIRLGNQDASDEEVYEAAKKVQLHDFIMSMPDGYHTQMSEMGERFSGGERGRIALARILLQNTPIVILDEPTVGLDPITERDLLATIFETLADKSLIWVTHHLVGAEKMDRVLFLEEGKTLMEGPHAELMAEEPRYKRLYQLDRPIEL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
CP025560_2	2.6\|548897\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	548897-548933	37	CP025560.1	2088424-2088460	0	1.0

1. spacer 2.6|548897|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to position: 2088424-2088460, mismatch: 0, identity: 1.0

gacactcatttttgctgcttgcttactagtgaccttt	CRISPR spacer
gacactcatttttgctgcttgcttactagtgaccttt	Protospacer
*************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
CP025560_2	2.19\|549732\|34\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549732-549765	34	MH341451	Listeria phage PSU-VKH-LP019, complete genome	29949-29982	0	1.0
CP025560_2	2.23\|549991\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549991-550026	36	NC_021539	Listeria phage LP-030-2, complete genome	32865-32900	0	1.0
CP025560_2	2.23\|549991\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549991-550026	36	NC_009812	Listeria phage B025, complete genome	37685-37720	0	1.0
CP025560_2	2.23\|549991\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549991-550026	36	KJ094023	Listeria phage LP-101, complete genome	38525-38560	0	1.0
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	MH299806	Listeria phage LP-KV022, complete genome	50264-50300	0	1.0
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	MN114083	Listeria phage LP-013, complete genome	45785-45821	0	1.0
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	NC_021785	Listeria phage LP-110, complete genome	7982-8018	0	1.0
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	MN128593	Listeria phage LP-031, complete genome	45080-45116	0	1.0
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	MN904502	Listeria phage LP-018, complete genome	45239-45275	0	1.0
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	KJ094021	Listeria phage LP-114, complete genome	35521-35557	0	1.0
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	MN114082	Listeria phage LP-010, complete genome	45070-45106	0	1.0
CP025560_2	2.41\|551157\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551157-551192	36	MH341453	Listeria phage PSU-VKH-LP041, complete genome	8839-8874	0	1.0
CP025560_2	2.41\|551157\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551157-551192	36	NC_009813	Listeria phage B054, complete genome	8839-8874	0	1.0
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	MH299806	Listeria phage LP-KV022, complete genome	37748-37783	0	1.0
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	MN114083	Listeria phage LP-013, complete genome	32794-32829	0	1.0
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	NC_021785	Listeria phage LP-110, complete genome	60594-60629	0	1.0
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	MN128593	Listeria phage LP-031, complete genome	32757-32792	0	1.0
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	JX442241	Listeria phage P70, complete genome	39110-39145	0	1.0
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	KJ094021	Listeria phage LP-114, complete genome	22470-22505	0	1.0
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	MN114082	Listeria phage LP-010, complete genome	32795-32830	0	1.0
CP025560_1	1.3\|532056\|33\|CP025560\|PILER-CR	532056-532088	33	NC_021539	Listeria phage LP-030-2, complete genome	18928-18960	1	0.97
CP025560_1	1.3\|532056\|33\|CP025560\|PILER-CR	532056-532088	33	KJ094023	Listeria phage LP-101, complete genome	22884-22916	1	0.97
CP025560_1	1.6\|532054\|36\|CP025560\|CRISPRCasFinder	532054-532089	36	NC_021539	Listeria phage LP-030-2, complete genome	18926-18961	1	0.972
CP025560_1	1.6\|532054\|36\|CP025560\|CRISPRCasFinder	532054-532089	36	KJ094023	Listeria phage LP-101, complete genome	22882-22917	1	0.972
CP025560_2	2.18\|549667\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549667-549702	36	DQ003637	Listeria phage A500, complete genome	28314-28349	1	0.972
CP025560_2	2.20\|549795\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549795-549831	37	NC_003216	Listeria phage A118, complete genome	29100-29136	1	0.973
CP025560_2	2.20\|549795\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549795-549831	37	AJ242593	Bacteriophage A118 complete genome	29100-29136	1	0.973
CP025560_2	2.20\|549795\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549795-549831	37	KJ094022	Listeria phage LP-030-3, complete genome	36308-36344	1	0.973
CP025560_2	2.20\|549795\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549795-549831	37	DQ003642	Listeria phage A006, complete genome	25889-25925	1	0.973
CP025560_2	2.23\|549991\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549991-550026	36	MT500540	Listeria phage LP-HM00113468, complete genome	10614-10649	1	0.972
CP025560_2	2.23\|549991\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549991-550026	36	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	204282-204317	1	0.972
CP025560_2	2.23\|549991\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549991-550026	36	AJ312240	Bacteriophage PSA complete genome	32207-32242	1	0.972
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	NC_021787	Listeria phage LP-037, complete genome	55165-55200	1	0.972
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	MN904502	Listeria phage LP-018, complete genome	32251-32286	1	0.972
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	KJ094020	Listeria phage LP-026, complete genome	15255-15290	1	0.972
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	JB137888	Sequence 7 from Patent WO2012159774	15092-15127	1	0.972
CP025560_2	2.46\|551485\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551485-551520	36	KJ094025	Listeria phage LP-032 contig 2, partial genome	4732-4767	1	0.972
CP025560_2	2.48\|551615\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551615-551651	37	KY705255	Streptococcus phage P0095, complete genome	33666-33702	1	0.973
CP025560_2	2.48\|551615\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551615-551651	37	KY705251	Streptococcus phage P0091, complete genome	32778-32814	1	0.973
CP025560_2	2.48\|551615\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551615-551651	37	KX879643	Streptococcus phage CHPC1151, complete genome	31697-31733	1	0.973
CP025560_2	2.48\|551615\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551615-551651	37	MK202161	Streptococcus phage CHPC1282, complete genome	32484-32520	1	0.973
CP025560_2	2.48\|551615\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551615-551651	37	KY705252	Streptococcus phage P0092, complete genome	31845-31881	1	0.973
CP025560_2	2.48\|551615\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551615-551651	37	MH937506	Streptococcus phage CHPC1148, complete genome	35552-35588	1	0.973
CP025560_2	2.48\|551615\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551615-551651	37	KY705253	Streptococcus phage P0093, complete genome	32631-32667	1	0.973
CP025560_2	2.48\|551615\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551615-551651	37	KY705254	Streptococcus phage P0094, complete genome	31034-31070	1	0.973
CP025560_1	1.1\|531927\|35\|CP025560\|PILER-CR	531927-531961	35	NC_009812	Listeria phage B025, complete genome	30705-30739	2	0.943
CP025560_1	1.3\|532056\|33\|CP025560\|PILER-CR	532056-532088	33	NC_009812	Listeria phage B025, complete genome	23383-23415	2	0.939
CP025560_1	1.6\|532054\|36\|CP025560\|CRISPRCasFinder	532054-532089	36	NC_009812	Listeria phage B025, complete genome	23381-23416	2	0.944
CP025560_2	2.18\|549667\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549667-549702	36	KP399677	Listeria phage vB_LmoS_188, complete genome	27966-28001	2	0.944
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	JB137888	Sequence 7 from Patent WO2012159774	3047-3083	2	0.946
CP025560_2	2.44\|551355\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551355-551389	35	NC_009813	Listeria phage B054, complete genome	21546-21580	2	0.943
CP025560_2	2.45\|551419\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551419-551455	37	KJ094023	Listeria phage LP-101, complete genome	37501-37537	2	0.946
CP025560_2	2.48\|551615\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551615-551651	37	MN689509	Lactococcus phage CHPC1175, complete genome	29544-29580	2	0.946
CP025560_2	2.48\|551615\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551615-551651	37	MK448735	Streptococcus phage Javan349, complete genome	11483-11519	2	0.946
CP025560_1	1.4\|531925\|38\|CP025560\|CRISPRCasFinder	531925-531962	38	NC_009812	Listeria phage B025, complete genome	30704-30741	3	0.921
CP025560_2	2.10\|549155\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549155-549189	35	MN114083	Listeria phage LP-013, complete genome	47787-47821	3	0.914
CP025560_2	2.10\|549155\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549155-549189	35	MN128593	Listeria phage LP-031, complete genome	47076-47110	3	0.914
CP025560_2	2.10\|549155\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549155-549189	35	MN904502	Listeria phage LP-018, complete genome	47235-47269	3	0.914
CP025560_2	2.10\|549155\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549155-549189	35	JX442241	Listeria phage P70, complete genome	54394-54428	3	0.914
CP025560_2	2.10\|549155\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549155-549189	35	MN114082	Listeria phage LP-010, complete genome	47072-47106	3	0.914
CP025560_2	2.14\|549411\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549411-549445	35	JX442241	Listeria phage P70, complete genome	53355-53389	3	0.914
CP025560_2	2.14\|549411\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549411-549445	35	KJ094021	Listeria phage LP-114, complete genome	37448-37482	3	0.914
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	KJ094026	Listeria phage LP-032 contig 3, partial genome	12567-12603	3	0.919
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	NC_021787	Listeria phage LP-037, complete genome	2448-2484	3	0.919
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	JX442241	Listeria phage P70, complete genome	51699-51735	3	0.919
CP025560_2	2.24\|550056\|37\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550056-550092	37	KJ094020	Listeria phage LP-026, complete genome	28599-28635	3	0.919
CP025560_2	2.14\|549411\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549411-549445	35	MH299806	Listeria phage LP-KV022, complete genome	51910-51944	4	0.886
CP025560_2	2.14\|549411\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549411-549445	35	NC_021785	Listeria phage LP-110, complete genome	9628-9662	4	0.886
CP025560_2	2.14\|549411\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549411-549445	35	MN128593	Listeria phage LP-031, complete genome	46726-46760	4	0.886
CP025560_2	2.14\|549411\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549411-549445	35	NC_021787	Listeria phage LP-037, complete genome	4105-4139	4	0.886
CP025560_2	2.14\|549411\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549411-549445	35	MN904502	Listeria phage LP-018, complete genome	46883-46917	4	0.886
CP025560_2	2.14\|549411\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549411-549445	35	KJ094020	Listeria phage LP-026, complete genome	30257-30291	4	0.886
CP025560_2	2.14\|549411\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549411-549445	35	JB137888	Sequence 7 from Patent WO2012159774	1403-1437	4	0.886
CP025560_2	2.14\|549411\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549411-549445	35	KJ094026	Listeria phage LP-032 contig 3, partial genome	10911-10945	4	0.886
CP025560_2	2.37\|550899\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550899-550934	36	FW590615	JP 2010534058-A/25: ANTIBIOTIC RESISTANCE FREE LISTERIA STRAINS AND METHODS FOR CONSTRUCTING AND USING SAME	3844-3879	4	0.889
CP025560_2	2.37\|550899\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550899-550934	36	HI504184	Sequence 26 from Patent EP2147092	3844-3879	4	0.889
CP025560_2	2.37\|550899\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550899-550934	36	AJ417489	bacteriophage U153 int gene for U153 integrase	3844-3879	4	0.889
CP025560_1	1.3\|532056\|33\|CP025560\|PILER-CR	532056-532088	33	MT362618	Microcystis phage MaeS, complete genome	46980-47012	6	0.818
CP025560_2	2.49\|551681\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551681-551715	35	MN694189	Marine virus AFVG_250M578, complete genome	47879-47913	6	0.829
CP025560_1	1.3\|532056\|33\|CP025560\|PILER-CR	532056-532088	33	NZ_CP040783	Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence	377953-377985	7	0.788
CP025560_1	1.3\|532056\|33\|CP025560\|PILER-CR	532056-532088	33	NZ_CP014284	Bacillus thuringiensis strain Bt185 plasmid pBT1850294, complete sequence	53826-53858	7	0.788
CP025560_1	1.3\|532056\|33\|CP025560\|PILER-CR	532056-532088	33	NZ_CP044980	Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence	39495-39527	7	0.788
CP025560_1	1.3\|532056\|33\|CP025560\|PILER-CR	532056-532088	33	NZ_CP032609	Bacillus thuringiensis strain QZL38 plasmid p.2, complete sequence	145727-145759	7	0.788
CP025560_2	2.12\|549284\|34\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549284-549317	34	MN693604	Marine virus AFVG_25M287, complete genome	25535-25568	7	0.794
CP025560_2	2.4\|548765\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	548765-548800	36	MH299806	Listeria phage LP-KV022, complete genome	32959-32994	8	0.778
CP025560_2	2.4\|548765\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	548765-548800	36	KJ094025	Listeria phage LP-032 contig 2, partial genome	9515-9550	8	0.778
CP025560_2	2.4\|548765\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	548765-548800	36	MN114083	Listeria phage LP-013, complete genome	28005-28040	8	0.778
CP025560_2	2.4\|548765\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	548765-548800	36	NC_021785	Listeria phage LP-110, complete genome	55805-55840	8	0.778
CP025560_2	2.4\|548765\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	548765-548800	36	MN128593	Listeria phage LP-031, complete genome	27968-28003	8	0.778
CP025560_2	2.4\|548765\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	548765-548800	36	NC_021787	Listeria phage LP-037, complete genome	50382-50417	8	0.778
CP025560_2	2.4\|548765\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	548765-548800	36	MN904502	Listeria phage LP-018, complete genome	27468-27503	8	0.778
CP025560_2	2.4\|548765\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	548765-548800	36	KJ094020	Listeria phage LP-026, complete genome	10472-10507	8	0.778
CP025560_2	2.37\|550899\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550899-550934	36	NC_019743	Microcoleus sp. PCC 7113 plasmid pMIC7113.08, complete sequence	4997-5032	8	0.778
CP025560_2	2.4\|548765\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	548765-548800	36	JX442241	Listeria phage P70, complete genome	33533-33568	9	0.75
CP025560_2	2.9\|549091\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549091-549125	35	NC_014457	Clostridium phage phiCTP1, complete genome	12063-12097	9	0.743
CP025560_2	2.27\|550251\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550251-550285	35	NZ_CP043831	Bacillus sp. BS98 plasmid unnamed1	257925-257959	9	0.743
CP025560_2	2.28\|550315\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550315-550349	35	NC_014533	Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence	491525-491559	9	0.743
CP025560_2	2.49\|551681\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551681-551715	35	MK448625	Streptococcus satellite phage Javan738, complete genome	5960-5994	9	0.743
CP025560_2	2.49\|551681\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551681-551715	35	MK448449	Streptococcus satellite phage Javan356, complete genome	4490-4524	9	0.743
CP025560_2	2.49\|551681\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551681-551715	35	MK448636	Streptococcus satellite phage Javan749, complete genome	6112-6146	9	0.743
CP025560_2	2.49\|551681\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551681-551715	35	NZ_CP045037	Lactobacillus mali strain LM596 plasmid unnamed2, complete sequence	34734-34768	9	0.743
CP025560_2	2.49\|551681\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551681-551715	35	NZ_CP018177	Lactobacillus hordei strain TMW 1.1822 plasmid pL11822-1, complete sequence	11325-11359	9	0.743
CP025560_2	2.49\|551681\|35\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	551681-551715	35	NZ_CP018181	Lactobacillus nagelii strain TMW 1.1827 plasmid pL11827-1, complete sequence	63608-63642	9	0.743
CP025560_2	2.8\|549028\|34\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	549028-549061	34	MK448457	Streptococcus satellite phage Javan368, complete genome	7593-7626	10	0.706
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	JB137888	Sequence 7 from Patent WO2012159774	31327-31362	10	0.722
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	KJ094025	Listeria phage LP-032 contig 2, partial genome	20716-20751	10	0.722
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	MH299806	Listeria phage LP-KV022, complete genome	22298-22333	10	0.722
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	MN114083	Listeria phage LP-013, complete genome	16804-16839	10	0.722
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	NC_021785	Listeria phage LP-110, complete genome	45144-45179	10	0.722
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	MN128593	Listeria phage LP-031, complete genome	16783-16818	10	0.722
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	NC_021787	Listeria phage LP-037, complete genome	39197-39232	10	0.722
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	MN904502	Listeria phage LP-018, complete genome	16804-16839	10	0.722
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	KJ094020	Listeria phage LP-026, complete genome	66347-66382	10	0.722
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	KJ094021	Listeria phage LP-114, complete genome	5711-5746	10	0.722
CP025560_2	2.30\|550444\|36\|CP025560\|PILER-CR,CRISPRCasFinder,CRT	550444-550479	36	MN114082	Listeria phage LP-010, complete genome	16805-16840	10	0.722

1. spacer 2.19|549732|34|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MH341451 (Listeria phage PSU-VKH-LP019, complete genome) position: , mismatch: 0, identity: 1.0

acattcgaagtggagtggcaacaaaagccttata	CRISPR spacer
acattcgaagtggagtggcaacaaaagccttata	Protospacer
**********************************

2. spacer 2.23|549991|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 0, identity: 1.0

gttgaaaagcgcaccattgttttaatttttttaatt	CRISPR spacer
gttgaaaagcgcaccattgttttaatttttttaatt	Protospacer
************************************

3. spacer 2.23|549991|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 0, identity: 1.0

gttgaaaagcgcaccattgttttaatttttttaatt	CRISPR spacer
gttgaaaagcgcaccattgttttaatttttttaatt	Protospacer
************************************

4. spacer 2.23|549991|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 0, identity: 1.0

gttgaaaagcgcaccattgttttaatttttttaatt	CRISPR spacer
gttgaaaagcgcaccattgttttaatttttttaatt	Protospacer
************************************

5. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MH299806 (Listeria phage LP-KV022, complete genome) position: , mismatch: 0, identity: 1.0

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcggactgacg	Protospacer
*************************************

6. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN114083 (Listeria phage LP-013, complete genome) position: , mismatch: 0, identity: 1.0

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcggactgacg	Protospacer
*************************************

7. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021785 (Listeria phage LP-110, complete genome) position: , mismatch: 0, identity: 1.0

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcggactgacg	Protospacer
*************************************

8. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN128593 (Listeria phage LP-031, complete genome) position: , mismatch: 0, identity: 1.0

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcggactgacg	Protospacer
*************************************

9. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN904502 (Listeria phage LP-018, complete genome) position: , mismatch: 0, identity: 1.0

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcggactgacg	Protospacer
*************************************

10. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094021 (Listeria phage LP-114, complete genome) position: , mismatch: 0, identity: 1.0

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcggactgacg	Protospacer
*************************************

11. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN114082 (Listeria phage LP-010, complete genome) position: , mismatch: 0, identity: 1.0

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcggactgacg	Protospacer
*************************************

12. spacer 2.41|551157|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MH341453 (Listeria phage PSU-VKH-LP041, complete genome) position: , mismatch: 0, identity: 1.0

aaaggtaaaaatattcttgctgtggcaggtcctgat	CRISPR spacer
aaaggtaaaaatattcttgctgtggcaggtcctgat	Protospacer
************************************

13. spacer 2.41|551157|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_009813 (Listeria phage B054, complete genome) position: , mismatch: 0, identity: 1.0

aaaggtaaaaatattcttgctgtggcaggtcctgat	CRISPR spacer
aaaggtaaaaatattcttgctgtggcaggtcctgat	Protospacer
************************************

14. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MH299806 (Listeria phage LP-KV022, complete genome) position: , mismatch: 0, identity: 1.0

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaagagacatc	Protospacer
************************************

15. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN114083 (Listeria phage LP-013, complete genome) position: , mismatch: 0, identity: 1.0

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaagagacatc	Protospacer
************************************

16. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021785 (Listeria phage LP-110, complete genome) position: , mismatch: 0, identity: 1.0

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaagagacatc	Protospacer
************************************

17. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN128593 (Listeria phage LP-031, complete genome) position: , mismatch: 0, identity: 1.0

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaagagacatc	Protospacer
************************************

18. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to JX442241 (Listeria phage P70, complete genome) position: , mismatch: 0, identity: 1.0

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaagagacatc	Protospacer
************************************

19. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094021 (Listeria phage LP-114, complete genome) position: , mismatch: 0, identity: 1.0

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaagagacatc	Protospacer
************************************

20. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN114082 (Listeria phage LP-010, complete genome) position: , mismatch: 0, identity: 1.0

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaagagacatc	Protospacer
************************************

21. spacer 1.3|532056|33|CP025560|PILER-CR matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.97

aaaacatccttcactgtatcaactcctttctat	CRISPR spacer
aaaacatccttcactgtctcaactcctttctat	Protospacer
***************** ***************

22. spacer 1.3|532056|33|CP025560|PILER-CR matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.97

aaaacatccttcactgtatcaactcctttctat	CRISPR spacer
aaaacatccttcactgtctcaactcctttctat	Protospacer
***************** ***************

23. spacer 1.6|532054|36|CP025560|CRISPRCasFinder matches to NC_021539 (Listeria phage LP-030-2, complete genome) position: , mismatch: 1, identity: 0.972

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctata	Protospacer
******************* ****************

24. spacer 1.6|532054|36|CP025560|CRISPRCasFinder matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 1, identity: 0.972

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactgtctcaactcctttctata	Protospacer
******************* ****************

25. spacer 2.18|549667|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to DQ003637 (Listeria phage A500, complete genome) position: , mismatch: 1, identity: 0.972

ttcgaaaagtctgttttgccctatgtctaatccttt	CRISPR spacer
ttcgaaaagtctgttttgcccgatgtctaatccttt	Protospacer
********************* **************

26. spacer 2.20|549795|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_003216 (Listeria phage A118, complete genome) position: , mismatch: 1, identity: 0.973

aagttaattattgaatgctatccagaaagaatagaag	CRISPR spacer
aagttaattattgaatgctatccagaaagaatagatg	Protospacer
*********************************** *

27. spacer 2.20|549795|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to AJ242593 (Bacteriophage A118 complete genome) position: , mismatch: 1, identity: 0.973

aagttaattattgaatgctatccagaaagaatagaag	CRISPR spacer
aagttaattattgaatgctatccagaaagaatagatg	Protospacer
*********************************** *

28. spacer 2.20|549795|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094022 (Listeria phage LP-030-3, complete genome) position: , mismatch: 1, identity: 0.973

aagttaattattgaatgctatccagaaagaatagaag	CRISPR spacer
aagttaattattgaatgctatccagaaagaatagatg	Protospacer
*********************************** *

29. spacer 2.20|549795|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to DQ003642 (Listeria phage A006, complete genome) position: , mismatch: 1, identity: 0.973

aagttaattattgaatgctatccagaaagaatagaag	CRISPR spacer
aagttaattattgaatgctatccagaaagaatagacg	Protospacer
*********************************** *

30. spacer 2.23|549991|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MT500540 (Listeria phage LP-HM00113468, complete genome) position: , mismatch: 1, identity: 0.972

gttgaaaagcgcaccattgttttaatttttttaatt	CRISPR spacer
gttgaaaagcgcaccattgttttaagttttttaatt	Protospacer
************************* **********

31. spacer 2.23|549991|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 1, identity: 0.972

gttgaaaagcgcaccattgttttaatttttttaatt	CRISPR spacer
gttgaaaagcgcaccattgctttaatttttttaatt	Protospacer
*******************.****************

32. spacer 2.23|549991|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to AJ312240 (Bacteriophage PSA complete genome) position: , mismatch: 1, identity: 0.972

gttgaaaagcgcaccattgttttaatttttttaatt	CRISPR spacer
gttgaaaagcgcaccattgctttaatttttttaatt	Protospacer
*******************.****************

33. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021787 (Listeria phage LP-037, complete genome) position: , mismatch: 1, identity: 0.972

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaggagacatc	Protospacer
***************************.********

34. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN904502 (Listeria phage LP-018, complete genome) position: , mismatch: 1, identity: 0.972

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaggagacatc	Protospacer
***************************.********

35. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094020 (Listeria phage LP-026, complete genome) position: , mismatch: 1, identity: 0.972

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaggagacatc	Protospacer
***************************.********

36. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to JB137888 (Sequence 7 from Patent WO2012159774) position: , mismatch: 1, identity: 0.972

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaggagacatc	Protospacer
***************************.********

37. spacer 2.46|551485|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094025 (Listeria phage LP-032 contig 2, partial genome) position: , mismatch: 1, identity: 0.972

agagaaatctcaagagccagccaagcaagagacatc	CRISPR spacer
agagaaatctcaagagccagccaagcaggagacatc	Protospacer
***************************.********

38. spacer 2.48|551615|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KY705255 (Streptococcus phage P0095, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

39. spacer 2.48|551615|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KY705251 (Streptococcus phage P0091, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

40. spacer 2.48|551615|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KX879643 (Streptococcus phage CHPC1151, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

41. spacer 2.48|551615|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MK202161 (Streptococcus phage CHPC1282, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

42. spacer 2.48|551615|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KY705252 (Streptococcus phage P0092, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

43. spacer 2.48|551615|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MH937506 (Streptococcus phage CHPC1148, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

44. spacer 2.48|551615|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KY705253 (Streptococcus phage P0093, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

45. spacer 2.48|551615|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KY705254 (Streptococcus phage P0094, complete genome) position: , mismatch: 1, identity: 0.973

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgagtgttcattatcggacatctta	Protospacer
************** **********************

46. spacer 1.1|531927|35|CP025560|PILER-CR matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.943

tatttctcctacgcttttcttatttctgtaaataa	CRISPR spacer
tatttctcctgcgcttttcttatttttgtaaataa	Protospacer
**********.**************.*********

47. spacer 1.3|532056|33|CP025560|PILER-CR matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.939

aaaacatccttcactgtatcaactcctttctat	CRISPR spacer
aaaacatccttcactatctcaactcctttctat	Protospacer
***************.* ***************

48. spacer 1.6|532054|36|CP025560|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 2, identity: 0.944

ctaaaacatccttcactgtatcaactcctttctata	CRISPR spacer
ctaaaacatccttcactatctcaactcctttctata	Protospacer
*****************.* ****************

49. spacer 2.18|549667|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KP399677 (Listeria phage vB_LmoS_188, complete genome) position: , mismatch: 2, identity: 0.944

ttcgaaaagtctgttttgccctatgtctaatccttt	CRISPR spacer
ttcgaaaagcctgttttgccctatatctaatccttt	Protospacer
*********.**************.***********

50. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to JB137888 (Sequence 7 from Patent WO2012159774) position: , mismatch: 2, identity: 0.946

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcgaactggcg	Protospacer
*****************************.****.**

51. spacer 2.44|551355|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_009813 (Listeria phage B054, complete genome) position: , mismatch: 2, identity: 0.943

aaattttttgttgataagcatgcaggagcaaataa	CRISPR spacer
aaattttttgttgataagcatgcaggagcaaacat	Protospacer
********************************.*

52. spacer 2.45|551419|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094023 (Listeria phage LP-101, complete genome) position: , mismatch: 2, identity: 0.946

cagtgattatgctaagacctacacaatcgttatcact	CRISPR spacer
cggtgattatgctaagacctacacaatcgttatcatt	Protospacer
*.*********************************.*

53. spacer 2.48|551615|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN689509 (Lactococcus phage CHPC1175, complete genome) position: , mismatch: 2, identity: 0.946

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaaccgagaacgtgtgttcattatcggacatctta	Protospacer
****** *******.**********************

54. spacer 2.48|551615|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MK448735 (Streptococcus phage Javan349, complete genome) position: , mismatch: 2, identity: 0.946

caaaacagagaacgcgtgttcattatcggacatctta	CRISPR spacer
caaaacagagaacgggtgttcattgtcggacatctta	Protospacer
************** *********.************

55. spacer 1.4|531925|38|CP025560|CRISPRCasFinder matches to NC_009812 (Listeria phage B025, complete genome) position: , mismatch: 3, identity: 0.921

tttatttctcctacgcttttcttatttctgtaaataag	CRISPR spacer
tttatttctcctgcgcttttcttatttttgtaaataaa	Protospacer
************.**************.*********.

56. spacer 2.10|549155|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN114083 (Listeria phage LP-013, complete genome) position: , mismatch: 3, identity: 0.914

ttaccaccaaagtccctacactcaataccaccaaa	CRISPR spacer
ttaccaccaaagtcccaacactcaatactaccaac	Protospacer
**************** ***********.*****

57. spacer 2.10|549155|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN128593 (Listeria phage LP-031, complete genome) position: , mismatch: 3, identity: 0.914

ttaccaccaaagtccctacactcaataccaccaaa	CRISPR spacer
ttaccaccaaagttcctacactcaatactaccaac	Protospacer
*************.**************.*****

58. spacer 2.10|549155|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN904502 (Listeria phage LP-018, complete genome) position: , mismatch: 3, identity: 0.914

ttaccaccaaagtccctacactcaataccaccaaa	CRISPR spacer
ttaccaccaaagtcccaacactcaatactaccaac	Protospacer
**************** ***********.*****

59. spacer 2.10|549155|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to JX442241 (Listeria phage P70, complete genome) position: , mismatch: 3, identity: 0.914

ttaccaccaaagtccctacactcaataccaccaaa	CRISPR spacer
ttaccaccaaagtcccaacactcaatactaccaac	Protospacer
**************** ***********.*****

60. spacer 2.10|549155|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN114082 (Listeria phage LP-010, complete genome) position: , mismatch: 3, identity: 0.914

ttaccaccaaagtccctacactcaataccaccaaa	CRISPR spacer
ttaccaccaaagtcccaacactcaatactaccaac	Protospacer
**************** ***********.*****

61. spacer 2.14|549411|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to JX442241 (Listeria phage P70, complete genome) position: , mismatch: 3, identity: 0.914

aaagtaaatgccgtagaaacgtcctcacaaccaca	CRISPR spacer
aaagtaaaagccgtagaaacgtcctcacaacctaa	Protospacer
******** ***********************  *

62. spacer 2.14|549411|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094021 (Listeria phage LP-114, complete genome) position: , mismatch: 3, identity: 0.914

aaagtaaatgccgtagaaacgtcctcacaaccaca	CRISPR spacer
aaagtaaaagccgtagaaacgtcctcacaacctaa	Protospacer
******** ***********************  *

63. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094026 (Listeria phage LP-032 contig 3, partial genome) position: , mismatch: 3, identity: 0.919

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcgaattgatg	Protospacer
*****************************.*.***.*

64. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021787 (Listeria phage LP-037, complete genome) position: , mismatch: 3, identity: 0.919

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcgaattgatg	Protospacer
*****************************.*.***.*

65. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to JX442241 (Listeria phage P70, complete genome) position: , mismatch: 3, identity: 0.919

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcgaattgatg	Protospacer
*****************************.*.***.*

66. spacer 2.24|550056|37|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094020 (Listeria phage LP-026, complete genome) position: , mismatch: 3, identity: 0.919

ttttgtcgcataaattctttgatgtggcggactgacg	CRISPR spacer
ttttgtcgcataaattctttgatgtggcgaattgatg	Protospacer
*****************************.*.***.*

67. spacer 2.14|549411|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MH299806 (Listeria phage LP-KV022, complete genome) position: , mismatch: 4, identity: 0.886

aaagtaaatgccgtagaaacgtcctcacaaccaca	CRISPR spacer
aaagtaaaagccgtagaaacgtccccacaacctaa	Protospacer
******** ***************.*******  *

68. spacer 2.14|549411|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021785 (Listeria phage LP-110, complete genome) position: , mismatch: 4, identity: 0.886

aaagtaaatgccgtagaaacgtcctcacaaccaca	CRISPR spacer
aaagtaaaagccgtagaaacgtccccacaacctaa	Protospacer
******** ***************.*******  *

69. spacer 2.14|549411|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN128593 (Listeria phage LP-031, complete genome) position: , mismatch: 4, identity: 0.886

aaagtaaatgccgtagaaacgtcctcacaaccaca	CRISPR spacer
aaagtaaaagccgtagaaacgtccccacaacctaa	Protospacer
******** ***************.*******  *

70. spacer 2.14|549411|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021787 (Listeria phage LP-037, complete genome) position: , mismatch: 4, identity: 0.886

aaagtaaatgccgtagaaacgtcctcacaaccaca	CRISPR spacer
aaagtaaaagccgtagaaacgtccccacaacctaa	Protospacer
******** ***************.*******  *

71. spacer 2.14|549411|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN904502 (Listeria phage LP-018, complete genome) position: , mismatch: 4, identity: 0.886

aaagtaaatgccgtagaaacgtcctcacaaccaca	CRISPR spacer
aaagtaaaagccgtagaaacgtccccacaacctaa	Protospacer
******** ***************.*******  *

72. spacer 2.14|549411|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094020 (Listeria phage LP-026, complete genome) position: , mismatch: 4, identity: 0.886

aaagtaaatgccgtagaaacgtcctcacaaccaca	CRISPR spacer
aaagtaaaagccgtagaaacgtccccacaacctaa	Protospacer
******** ***************.*******  *

73. spacer 2.14|549411|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to JB137888 (Sequence 7 from Patent WO2012159774) position: , mismatch: 4, identity: 0.886

aaagtaaatgccgtagaaacgtcctcacaaccaca	CRISPR spacer
aaagtaaaagccgtagaaacgtccccacaacctaa	Protospacer
******** ***************.*******  *

74. spacer 2.14|549411|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094026 (Listeria phage LP-032 contig 3, partial genome) position: , mismatch: 4, identity: 0.886

aaagtaaatgccgtagaaacgtcctcacaaccaca	CRISPR spacer
aaagtaaaagccgtagaaacgtccccacaacctaa	Protospacer
******** ***************.*******  *

75. spacer 2.37|550899|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to FW590615 (JP 2010534058-A/25: ANTIBIOTIC RESISTANCE FREE LISTERIA STRAINS AND METHODS FOR CONSTRUCTING AND USING SAME) position: , mismatch: 4, identity: 0.889

gtgtaattcttaattccgtattgattcgctagtttt	CRISPR spacer
ttataatccttaattccgtattgatttgctagtttt	Protospacer
 *.****.******************.*********

76. spacer 2.37|550899|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to HI504184 (Sequence 26 from Patent EP2147092) position: , mismatch: 4, identity: 0.889

gtgtaattcttaattccgtattgattcgctagtttt	CRISPR spacer
ttataatccttaattccgtattgatttgctagtttt	Protospacer
 *.****.******************.*********

77. spacer 2.37|550899|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to AJ417489 (bacteriophage U153 int gene for U153 integrase) position: , mismatch: 4, identity: 0.889

gtgtaattcttaattccgtattgattcgctagtttt	CRISPR spacer
ttataatccttaattccgtattgatttgctagtttt	Protospacer
 *.****.******************.*********

78. spacer 1.3|532056|33|CP025560|PILER-CR matches to MT362618 (Microcystis phage MaeS, complete genome) position: , mismatch: 6, identity: 0.818

---aaaacatccttcactgtatcaactcctttctat	CRISPR spacer
gctaaaaaa---ttcactgtatcagctcctctctat	Protospacer
   **** *   ************.*****.*****

79. spacer 2.49|551681|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN694189 (Marine virus AFVG_250M578, complete genome) position: , mismatch: 6, identity: 0.829

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
taataaaaaatgagggcttagaaaatgaaaaaatt	Protospacer
*  *.*** ******.***************** *

80. spacer 1.3|532056|33|CP025560|PILER-CR matches to NZ_CP040783 (Bacillus thuringiensis strain HM-311 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.788

---aaaacatccttcactgtatcaactcctttctat	CRISPR spacer
tttaataga---ttcactgtatcaactccattatat	Protospacer
   ** * *   ***************** ** ***

81. spacer 1.3|532056|33|CP025560|PILER-CR matches to NZ_CP014284 (Bacillus thuringiensis strain Bt185 plasmid pBT1850294, complete sequence) position: , mismatch: 7, identity: 0.788

---aaaacatccttcactgtatcaactcctttctat	CRISPR spacer
tttaataga---ttcactgtatcaactccattatat	Protospacer
   ** * *   ***************** ** ***

82. spacer 1.3|532056|33|CP025560|PILER-CR matches to NZ_CP044980 (Bacillus thuringiensis strain BT62 plasmid pBT62B, complete sequence) position: , mismatch: 7, identity: 0.788

---aaaacatccttcactgtatcaactcctttctat	CRISPR spacer
tttaataga---ttcactgtatcaactccattatat	Protospacer
   ** * *   ***************** ** ***

83. spacer 1.3|532056|33|CP025560|PILER-CR matches to NZ_CP032609 (Bacillus thuringiensis strain QZL38 plasmid p.2, complete sequence) position: , mismatch: 7, identity: 0.788

---aaaacatccttcactgtatcaactcctttctat	CRISPR spacer
tttaataga---ttcactgtatcaactccattatat	Protospacer
   ** * *   ***************** ** ***

84. spacer 2.12|549284|34|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN693604 (Marine virus AFVG_25M287, complete genome) position: , mismatch: 7, identity: 0.794

ccatta--cgtttgccttgttgttaaagcttgcaac	CRISPR spacer
--attaatcgtttactttgttgttaaagcttgtgcc	Protospacer
  ****  *****.*.****************.. *

85. spacer 2.4|548765|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MH299806 (Listeria phage LP-KV022, complete genome) position: , mismatch: 8, identity: 0.778

caagaagcacgtaagatgtttgtagcaccagacaac	CRISPR spacer
ccagaagctcgtaagatgtttatagcaccacaaggg	Protospacer
* ****** ************.******** * ..

86. spacer 2.4|548765|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094025 (Listeria phage LP-032 contig 2, partial genome) position: , mismatch: 8, identity: 0.778

caagaagcacgtaagatgtttgtagcaccagacaac	CRISPR spacer
ccagaagctcgtaagatgtttatagcaccacaaggg	Protospacer
* ****** ************.******** * ..

87. spacer 2.4|548765|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN114083 (Listeria phage LP-013, complete genome) position: , mismatch: 8, identity: 0.778

caagaagcacgtaagatgtttgtagcaccagacaac	CRISPR spacer
ccagaagctcgtaagatgtttatagcaccacaaggg	Protospacer
* ****** ************.******** * ..

88. spacer 2.4|548765|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021785 (Listeria phage LP-110, complete genome) position: , mismatch: 8, identity: 0.778

caagaagcacgtaagatgtttgtagcaccagacaac	CRISPR spacer
ccagaagctcgtaagatgtttatagcaccacaaggg	Protospacer
* ****** ************.******** * ..

89. spacer 2.4|548765|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN128593 (Listeria phage LP-031, complete genome) position: , mismatch: 8, identity: 0.778

caagaagcacgtaagatgtttgtagcaccagacaac	CRISPR spacer
ccagaagctcgtaagatgtttatagcaccacaaggg	Protospacer
* ****** ************.******** * ..

90. spacer 2.4|548765|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021787 (Listeria phage LP-037, complete genome) position: , mismatch: 8, identity: 0.778

caagaagcacgtaagatgtttgtagcaccagacaac	CRISPR spacer
ccagaagctcgtaagatgtttatagcaccacaaggg	Protospacer
* ****** ************.******** * ..

91. spacer 2.4|548765|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN904502 (Listeria phage LP-018, complete genome) position: , mismatch: 8, identity: 0.778

caagaagcacgtaagatgtttgtagcaccagacaac	CRISPR spacer
ccagaagctcgtaagatgtttatagcaccacaaggg	Protospacer
* ****** ************.******** * ..

92. spacer 2.4|548765|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094020 (Listeria phage LP-026, complete genome) position: , mismatch: 8, identity: 0.778

caagaagcacgtaagatgtttgtagcaccagacaac	CRISPR spacer
ccagaagctcgtaagatgtttatagcaccacaaggg	Protospacer
* ****** ************.******** * ..

93. spacer 2.37|550899|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_019743 (Microcoleus sp. PCC 7113 plasmid pMIC7113.08, complete sequence) position: , mismatch: 8, identity: 0.778

gtgtaattcttaattccgtattgattcgctagtttt---	CRISPR spacer
gtgtaattcttactgccgtattgatt---taactctgaa	Protospacer
************ * ***********   **..*.*

94. spacer 2.4|548765|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to JX442241 (Listeria phage P70, complete genome) position: , mismatch: 9, identity: 0.75

caagaagcacgtaagatgtttgtagcaccagacaac	CRISPR spacer
ccagaagctcgtaagatgtttatagcaccgcaaggg	Protospacer
* ****** ************.*******. * ..

95. spacer 2.9|549091|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_014457 (Clostridium phage phiCTP1, complete genome) position: , mismatch: 9, identity: 0.743

tggtataaatctaaaaatacacaagttgtaaatgt	CRISPR spacer
aatggtaaatctaaaaataaacaagctgtaagtat	Protospacer
 .  .************** *****.*****.*.*

96. spacer 2.27|550251|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043831 (Bacillus sp. BS98 plasmid unnamed1) position: , mismatch: 9, identity: 0.743

tttatcactcctatgcttttcttatttctgtaaat	CRISPR spacer
tttatcactcctatgctttttatatactcctaata	Protospacer
********************. *** ... ***

97. spacer 2.28|550315|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_014533 (Gloeothece verrucosa PCC 7822 plasmid Cy782201, complete sequence) position: , mismatch: 9, identity: 0.743

gcttttttcaacaattttatcaccagatgtcatta	CRISPR spacer
agttttttcaacaattttatgaacagataattttt	Protospacer
. ****************** * *****. . **

98. spacer 2.49|551681|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MK448625 (Streptococcus satellite phage Javan738, complete genome) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
gtatgaactatgaggacttagaaagtgaagacctg	Protospacer
 * **** ****************.****.*

99. spacer 2.49|551681|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MK448449 (Streptococcus satellite phage Javan356, complete genome) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
gtatgaactatgaggacttagaaagtgaagacctg	Protospacer
 * **** ****************.****.*

100. spacer 2.49|551681|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MK448636 (Streptococcus satellite phage Javan749, complete genome) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
gtctgaactatgaggacttagaaagtgaagacctg	Protospacer
 *.**** ****************.****.*

101. spacer 2.49|551681|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045037 (Lactobacillus mali strain LM596 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
ttaagaaatataaggacttagtaaatgaagttatg	Protospacer
**  *******.********* *******.  *

102. spacer 2.49|551681|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018177 (Lactobacillus hordei strain TMW 1.1822 plasmid pL11822-1, complete sequence) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
ttaagaaatataaggacttagtaaatgaagttatg	Protospacer
**  *******.********* *******.  *

103. spacer 2.49|551681|35|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018181 (Lactobacillus nagelii strain TMW 1.1827 plasmid pL11827-1, complete sequence) position: , mismatch: 9, identity: 0.743

ttttgaaatatgaggacttagaaaatgaaaaaaat	CRISPR spacer
ttaagaaatataaggacttagtaaatgaagttatg	Protospacer
**  *******.********* *******.  *

104. spacer 2.8|549028|34|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MK448457 (Streptococcus satellite phage Javan368, complete genome) position: , mismatch: 10, identity: 0.706

cctgaaatgggggcttttttgtgatgaaaaacac	CRISPR spacer
acgaatctgggggcttttgtgagatgaaaaaaga	Protospacer
 * .*  *********** ** ********* .

105. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to JB137888 (Sequence 7 from Patent WO2012159774) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

106. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094025 (Listeria phage LP-032 contig 2, partial genome) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

107. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MH299806 (Listeria phage LP-KV022, complete genome) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

108. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN114083 (Listeria phage LP-013, complete genome) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

109. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021785 (Listeria phage LP-110, complete genome) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

110. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN128593 (Listeria phage LP-031, complete genome) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

111. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to NC_021787 (Listeria phage LP-037, complete genome) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

112. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN904502 (Listeria phage LP-018, complete genome) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

113. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094020 (Listeria phage LP-026, complete genome) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

114. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to KJ094021 (Listeria phage LP-114, complete genome) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

115. spacer 2.30|550444|36|CP025560|PILER-CR,CRISPRCasFinder,CRT matches to MN114082 (Listeria phage LP-010, complete genome) position: , mismatch: 10, identity: 0.722

atagattagtagggaaataatatgtaatggttactg	CRISPR spacer
tcattcctgtagggaaataataagtaatagttacag	Protospacer
 .*  .. ************** *****.***** *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

118768 : 125293

Listeria_phage(33.33%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU88535.1\|118768_119221_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	4.0e-31	47.9
AVU88536.1\|119226_119562_-	XRE family transcriptional regulator	A0A2H4JAR9	uncultured_Caudovirales_phage	4.0e-20	52.5
AVU88537.1\|119778_120207_+	hypothetical protein	NA	NA	NA	NA
AVU88538.1\|120218_120635_+	hypothetical protein	A8ASQ1	Listeria_phage	7.7e-21	39.3
AVU88539.1\|120912_121302_+	DUF5072 domain-containing protein	NA	NA	NA	NA
AVU88540.1\|121314_121827_+\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	1.2e-47	62.7
AVU88541.1\|121874_122177_+	segregation and condensation protein B	NA	NA	NA	NA
AVU88542.1\|122218_122623_+	phenylalanine racemase	NA	NA	NA	NA
AVU88543.1\|122609_124478_+	hypothetical protein	A0A097PAU2	Streptococcus_pyogenes_phage	3.5e-20	45.8
AVU88544.1\|124474_125293_+\|tail	phage tail family protein	A0A060AFE1	Staphylococcus_phage	7.2e-39	35.0

DBSCAN-SWA_2

682486 : 738867

Listeria_phage(42.42%)

transposase,portal,protease,integrase,tail,capsid,holin,terminase,head

attL 692180:692197|attR 727868:727885

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU89046.1\|682486_683638_-\|integrase	site-specific integrase	A8ATX2	Listeria_phage	3.4e-87	46.3
AVU89047.1\|683659_684373_-	hypothetical protein	NA	NA	NA	NA
AVU89048.1\|684427_684928_-	hypothetical protein	A0A1S7FYX8	Listeria_phage	1.9e-13	31.9
AVU89049.1\|684940_685267_-	XRE family transcriptional regulator	Q0H244	Geobacillus_phage	1.6e-13	47.1
AVU89050.1\|685440_685632_+	XRE family transcriptional regulator	Q0H243	Geobacillus_phage	4.7e-10	57.6
AVU89051.1\|685729_686056_+	DUF771 domain-containing protein	A0A2H4J474	uncultured_Caudovirales_phage	4.9e-15	41.1
AVU89052.1\|686228_687143_+	hypothetical protein	A0A1W6JNI1	Staphylococcus_phage	7.8e-58	51.5
AVU89053.1\|687144_687501_+	MerR family transcriptional regulator	NA	NA	NA	NA
AVU89054.1\|687497_687914_+	hypothetical protein	NA	NA	NA	NA
AVU89055.1\|688101_688821_+	DUF2786 domain-containing protein	A0A1U9WR73	Streptococcus_virus	3.5e-21	29.7
AVU89056.1\|688824_689127_+	hypothetical protein	A0A059T695	Listeria_phage	3.3e-21	94.3
AVU89057.1\|689123_689525_+	hypothetical protein	A8ASP1	Listeria_phage	6.0e-39	58.2
AVU89058.1\|689521_690007_+	pentapeptide repeat-containing protein	A0A059T6G6	Listeria_phage	2.0e-44	93.2
AVU89059.1\|690003_690465_+	hypothetical protein	D9J0I6	Brochothrix_phage	6.7e-18	35.9
AVU89060.1\|690461_690845_+	preprotein translocase subunit YajC	A8ATZ3	Listeria_phage	5.4e-45	77.2
AVU89061.1\|690865_691114_+	DUF3850 domain-containing protein	A0A059T7N3	Listeria_phage	5.0e-28	84.0
AVU89062.1\|691113_691695_+	DUF3310 domain-containing protein	A0A059T5J6	Listeria_phage	2.3e-76	76.3
AVU89063.1\|691694_692174_+	single-stranded DNA-binding protein	A8ASP5	Listeria_phage	2.3e-69	83.8
692180:692197	attL	NA	NA	NA	NA
AVU89064.1\|692194_692434_+	hypothetical protein	NA	NA	NA	NA
AVU89065.1\|692424_692610_+	hypothetical protein	NA	NA	NA	NA
AVU89066.1\|692680_693199_+	RNA polymerase subunit sigma	NA	NA	NA	NA
AVU89067.1\|693195_693738_+\|integrase	site-specific integrase	H0USV4	Bacillus_phage	2.5e-48	53.3
AVU89068.1\|693753_694086_+	hypothetical protein	NA	NA	NA	NA
AVU89069.1\|694356_694683_+	hypothetical protein	NA	NA	NA	NA
AVU89070.1\|694679_695039_+	HNH endonuclease	A0A075M5R4	Enterococcus_phage	5.4e-15	46.2
AVU89071.1\|695137_695665_+\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	6.1e-31	46.7
AVU89072.1\|695633_697385_+\|terminase	terminase large subunit	A0A2H4JCI4	uncultured_Caudovirales_phage	4.1e-156	50.7
AVU89073.1\|697391_697592_+	DUF1056 domain-containing protein	NA	NA	NA	NA
AVU89074.1\|697594_698830_+\|portal	phage portal protein	A0A2H4JAR2	uncultured_Caudovirales_phage	3.6e-82	42.1
AVU89075.1\|698826_699393_+\|head,protease	HK97 family phage prohead protease	A0A1D6Z2A7	Staphylococcus_phage	1.0e-44	52.2
AVU89076.1\|699450_700626_+\|capsid	phage major capsid protein	A0A060AI54	Enterococcus_phage	2.2e-44	38.1
AVU89077.1\|700674_701013_+\|head,tail	phage gp6-like head-tail connector protein	A0A2H4JB77	uncultured_Caudovirales_phage	8.1e-13	37.8
AVU89078.1\|700982_701303_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
AVU89079.1\|701296_701662_+	hypothetical protein	NA	NA	NA	NA
AVU89080.1\|701664_702063_+	hypothetical protein	NA	NA	NA	NA
AVU91334.1\|702083_702659_+\|tail	phage tail protein	M1PRQ7	Streptococcus_phage	1.2e-32	42.4
AVU89081.1\|702748_703096_+	hypothetical protein	NA	NA	NA	NA
AVU89082.1\|703292_707492_+\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.2e-12	33.0
AVU89083.1\|707484_709728_+\|tail	phage tail protein	A0A059T682	Listeria_phage	1.2e-56	29.4
AVU89084.1\|709733_712025_+	hypothetical protein	A0A059T7Y6	Listeria_phage	4.4e-134	37.9
AVU89085.1\|712017_713079_+	hypothetical protein	A0A059T7R4	Listeria_phage	1.2e-94	51.0
AVU89086.1\|713117_713483_+	hypothetical protein	Q9T1A0	Listeria_phage	7.4e-12	100.0
AVU89087.1\|713495_713780_+\|holin	holin	A8ASL4	Listeria_phage	3.5e-41	94.6
AVU89088.1\|716013_716928_+	peptidase	NA	NA	NA	NA
AVU89089.1\|716927_717287_+	DUF3221 domain-containing protein	NA	NA	NA	NA
AVU89090.1\|717818_718352_+	transcriptional regulator	NA	NA	NA	NA
AVU89091.1\|718415_719333_+	aldo/keto reductase	NA	NA	NA	NA
AVU89092.1\|721564_722293_+	hypothetical protein	NA	NA	NA	NA
AVU89093.1\|722435_723086_+	transaldolase	M4SLG0	Cyanophage	2.6e-15	30.2
AVU89094.1\|723128_724949_-	LTA synthase family protein	W6LM83	Streptococcus_phage	2.2e-48	28.3
AVU89095.1\|725183_726575_+	amino acid transporter	NA	NA	NA	NA
AVU89096.1\|726663_727503_+	glyoxalase	NA	NA	NA	NA
AVU89097.1\|727585_727870_-	hypothetical protein	NA	NA	NA	NA
AVU89098.1\|727967_728918_+	magnesium transporter CorA family protein	NA	NA	NA	NA
727868:727885	attR	NA	NA	NA	NA
AVU89099.1\|728941_729583_+	GntR family transcriptional regulator	NA	NA	NA	NA
AVU89100.1\|729625_732316_+	YhgE/Pip domain-containing protein	NA	NA	NA	NA
AVU89101.1\|732361_733009_+	GntR family transcriptional regulator	NA	NA	NA	NA
AVU89102.1\|733017_733554_-	N-acetyltransferase	NA	NA	NA	NA
AVU91335.1\|733540_734461_-	DUF975 domain-containing protein	NA	NA	NA	NA
AVU89103.1\|734651_734861_+	hypothetical protein	NA	NA	NA	NA
AVU89104.1\|734928_735636_+	serine/threonine protein phosphatase	A0A249Y183	Enterococcus_phage	2.5e-19	27.8
AVU89105.1\|735679_736243_-	DUF420 domain-containing protein	NA	NA	NA	NA
AVU89106.1\|736362_736779_+	hypothetical protein	NA	NA	NA	NA
AVU89107.1\|736830_737466_+	endonuclease III domain-containing protein	NA	NA	NA	NA
AVU89108.1\|737455_738352_-	Rgg family transcriptional regulator	NA	NA	NA	NA
AVU89109.1\|738582_738867_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1158399 : 1165823

Hokovirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU89533.1\|1158399_1158783_+	glycerol-3-phosphate cytidylyltransferase	A0A1V0SGE7	Hokovirus	1.4e-16	40.7
AVU89534.1\|1158804_1159788_+	glycosyltransferase family 2 protein	A0A1V0SAH6	Catovirus	4.1e-12	34.6
AVU89535.1\|1159802_1160816_+	glycosyl transferase	A0A1V0SAH6	Catovirus	7.9e-11	32.0
AVU89536.1\|1161024_1162515_+	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	9.5e-114	49.7
AVU89537.1\|1162526_1163351_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	4.4e-68	52.9
AVU89538.1\|1163363_1163672_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
AVU89539.1\|1163733_1164138_+	PTS sugar transporter subunit IIB	NA	NA	NA	NA
AVU89540.1\|1164266_1165823_+	GMP synthase (glutamine-hydrolyzing)	A0A1V0SH76	Hokovirus	2.3e-17	28.1

DBSCAN-SWA_4

1252466 : 1354315

113

Listeria_phage(70.49%)

portal,protease,integrase,tail,capsid,holin,terminase,head,tRNA

attL 1259742:1259758|attR 1298418:1298434

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU89645.1\|1252466_1253519_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	1.3e-29	34.9
AVU89646.1\|1253518_1255927_+\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
AVU89647.1\|1256087_1256789_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.0e-33	35.4
AVU89648.1\|1256802_1260213_+	ABC transporter permease	NA	NA	NA	NA
1259742:1259758	attL	NA	NA	NA	NA
AVU89649.1\|1260310_1260763_+	MarR family transcriptional regulator	NA	NA	NA	NA
AVU89650.1\|1260778_1263979_+	MMPL family transporter	NA	NA	NA	NA
AVU89651.1\|1264085_1264760_+	uracil-DNA glycosylase	A0A172DS90	Canid_alphaherpesvirus	1.7e-49	47.7
AVU89652.1\|1264796_1265723_-	ribonuclease HIII	NA	NA	NA	NA
AVU89653.1\|1265876_1266140_+	cell division protein ZapA	NA	NA	NA	NA
AVU89654.1\|1266139_1266682_+	colicin V synthesis protein	NA	NA	NA	NA
AVU89655.1\|1266774_1268487_+	DNA polymerase/3'-5' exonuclease PolX	A0A2H4UV14	Bodo_saltans_virus	3.9e-18	24.8
AVU89656.1\|1268509_1270867_+	endonuclease MutS2	Q94M10	Lactobacillus_phage	1.0e-21	50.4
AVU89657.1\|1270947_1271259_+	thiol reductase thioredoxin	A0A1X9I9P5	Staphylococcus_phage	5.4e-19	39.6
AVU89658.1\|1271334_1273146_+	excinuclease ABC subunit UvrC	NA	NA	NA	NA
AVU89659.1\|1273334_1274549_+	aspartate kinase	NA	NA	NA	NA
AVU89660.1\|1274604_1275099_-	DUF2507 domain-containing protein	NA	NA	NA	NA
AVU89661.1\|1275246_1276047_+	glutamate racemase	NA	NA	NA	NA
AVU89662.1\|1276059_1276806_+	ribonuclease PH	NA	NA	NA	NA
AVU89663.1\|1276809_1277421_+	non-canonical purine NTP pyrophosphatase	NA	NA	NA	NA
AVU89664.1\|1277457_1277982_+	metallophosphoesterase	NA	NA	NA	NA
AVU89665.1\|1278266_1279421_-\|integrase	site-specific integrase	A0A059T688	Listeria_phage	3.0e-208	93.8
AVU89666.1\|1279575_1280385_-	hypothetical protein	NA	NA	NA	NA
AVU89667.1\|1280404_1280974_-	DUF4352 domain-containing protein	R4IBV3	Listeria_phage	4.1e-09	91.7
AVU89668.1\|1281024_1281477_-	ImmA/IrrE family metallo-endopeptidase	A0A059T7S0	Listeria_phage	1.4e-79	92.0
AVU89669.1\|1281493_1281817_-	XRE family transcriptional regulator	R4IDX0	Listeria_phage	5.0e-36	71.0
AVU89670.1\|1282084_1282288_+	hypothetical protein	NA	NA	NA	NA
AVU89671.1\|1282255_1282648_-	DUF2513 domain-containing protein	A0A1Q1PVT8	Staphylococcus_phage	2.2e-17	41.8
AVU89672.1\|1282714_1283038_+	hypothetical protein	NA	NA	NA	NA
AVU89673.1\|1283052_1283259_+	XRE family transcriptional regulator	Q8W5X9	Listeria_phage	4.6e-27	94.1
AVU89674.1\|1283261_1283504_+	hypothetical protein	Q8W5X8	Listeria_phage	9.2e-43	97.5
AVU89675.1\|1283506_1283692_+	hypothetical protein	A0A059T7Z3	Listeria_phage	4.6e-26	93.4
AVU89676.1\|1284417_1284717_+	hypothetical protein	A8ASN6	Listeria_phage	3.7e-41	92.2
AVU89677.1\|1284697_1285141_+	hypothetical protein	NA	NA	NA	NA
AVU89678.1\|1285157_1285715_+	DUF1642 domain-containing protein	A8ATD8	Listeria_phage	2.4e-46	50.5
AVU89679.1\|1285717_1285915_+	hypothetical protein	A0A0B5CU49	Listeria_phage	2.0e-27	95.4
AVU89680.1\|1285911_1286295_+	hypothetical protein	A0A0B5CYR4	Listeria_phage	2.3e-35	58.3
AVU89681.1\|1286291_1286687_+	hypothetical protein	A8ASP3	Listeria_phage	2.9e-38	78.8
AVU89682.1\|1286683_1287076_+	hypothetical protein	A8ATD9	Listeria_phage	6.9e-56	82.8
AVU89683.1\|1287179_1287452_+	hypothetical protein	A0A059T7Z9	Listeria_phage	1.5e-38	86.7
AVU89684.1\|1287448_1287643_+	hypothetical protein	A8ASP4	Listeria_phage	1.4e-22	79.7
AVU89685.1\|1287697_1288258_-	hypothetical protein	NA	NA	NA	NA
AVU89686.1\|1288529_1288730_+	hypothetical protein	A8ATE8	Listeria_phage	1.2e-11	55.4
AVU89687.1\|1288726_1289338_+	hypothetical protein	B6D7K1	Listeria_phage	4.0e-50	50.0
AVU89688.1\|1289353_1289587_+	hypothetical protein	NA	NA	NA	NA
AVU89689.1\|1289583_1290354_+	DUF1351 domain-containing protein	B6D7K2	Listeria_phage	6.6e-18	27.0
AVU89690.1\|1290356_1290992_+	hypothetical protein	NA	NA	NA	NA
AVU89691.1\|1291059_1292748_+	hypothetical protein	A8ATS1	Listeria_phage	5.2e-124	43.1
AVU89692.1\|1292750_1294556_+	DNA primase	A8ATS2	Listeria_phage	9.7e-129	40.8
AVU89693.1\|1294860_1295130_+	hypothetical protein	W0GBM0	Listeria_phage	9.6e-17	84.3
AVU91343.1\|1295240_1295771_+	DUF3310 domain-containing protein	A0A059T7T5	Listeria_phage	5.3e-67	72.3
AVU89694.1\|1295962_1296388_+	DUF722 domain-containing protein	A8ATF6	Listeria_phage	1.5e-72	98.6
AVU89695.1\|1296994_1297309_+	HNH endonuclease	A8ATF8	Listeria_phage	3.8e-57	99.0
AVU89696.1\|1297357_1297714_+	hypothetical protein	A0A059T7Y1	Listeria_phage	4.5e-46	97.0
AVU89697.1\|1297710_1299354_+\|terminase	terminase large subunit	A0A059T7Q8	Listeria_phage	0.0e+00	98.7
1298418:1298434	attR	NA	NA	NA	NA
AVU89698.1\|1299363_1299753_-	DUF2513 domain-containing protein	A0A2I7SCV0	Paenibacillus_phage	9.7e-18	36.4
AVU89699.1\|1299803_1300934_+\|portal	phage portal protein	A8AT96	Listeria_phage	3.9e-208	96.3
AVU89700.1\|1300930_1301647_+\|protease	Clp protease ClpP	A0A1S5SFF8	Streptococcus_phage	6.1e-66	56.5
AVU89701.1\|1301673_1302825_+\|capsid	phage major capsid protein	A8AT98	Listeria_phage	7.9e-201	92.7
AVU89702.1\|1303011_1303311_+	hypothetical protein	A0A059T7R0	Listeria_phage	1.3e-46	97.0
AVU89703.1\|1303294_1303660_+\|head,tail	phage head-tail adapter protein	A0A059T6F2	Listeria_phage	2.7e-62	96.7
AVU89704.1\|1303656_1304058_+	hypothetical protein	A8ATA2	Listeria_phage	3.4e-66	96.2
AVU89705.1\|1304054_1304438_+	DUF3168 domain-containing protein	A0A059T681	Listeria_phage	5.2e-64	94.5
AVU89706.1\|1304458_1305046_+\|tail	phage tail protein	A0A059T7Y4	Listeria_phage	2.4e-105	97.4
AVU89707.1\|1305115_1305448_+	hypothetical protein	A8ATA5	Listeria_phage	1.3e-47	90.9
AVU89708.1\|1305663_1310586_+\|tail	phage tail tape measure protein	A0A059T5F4	Listeria_phage	0.0e+00	95.5
AVU89709.1\|1310582_1312232_+\|tail	phage tail protein	A0A059T682	Listeria_phage	0.0e+00	98.9
AVU89710.1\|1312247_1314542_+	hypothetical protein	A0A059T7Y6	Listeria_phage	0.0e+00	97.5
AVU89711.1\|1314531_1315626_+	carbohydrate-binding protein CenC	A0A059T7R4	Listeria_phage	1.2e-201	97.3
AVU89712.1\|1315677_1315986_+	hypothetical protein	A0A059T5E6	Listeria_phage	3.9e-38	88.9
AVU89713.1\|1315985_1316252_+\|holin	phage holin	A0A059T684	Listeria_phage	2.8e-40	97.7
AVU89714.1\|1316251_1317097_+	peptidase M15	A0A059T7Y8	Listeria_phage	1.4e-138	94.7
AVU89715.1\|1317284_1317770_+	DUF4065 domain-containing protein	I6R0L8	Salmonella_phage	4.6e-17	40.6
AVU89716.1\|1318279_1318513_+	hypothetical protein	R4IDW6	Listeria_phage	1.0e-35	96.1
AVU89717.1\|1318509_1318692_+	hypothetical protein	A0A059T5E7	Listeria_phage	3.6e-07	50.9
AVU89718.1\|1318712_1319366_-	hypothetical protein	NA	NA	NA	NA
AVU89719.1\|1320159_1321518_+	DUF1254 domain-containing protein	NA	NA	NA	NA
AVU89720.1\|1321560_1322154_-	hypothetical protein	NA	NA	NA	NA
AVU89721.1\|1322307_1322715_-	VOC family protein	NA	NA	NA	NA
AVU89722.1\|1322879_1323479_+	histidine phosphatase family protein	A0A1X9IGJ2	Lactococcus_phage	5.8e-30	41.0
AVU89723.1\|1323510_1323771_-	hypothetical protein	NA	NA	NA	NA
AVU89724.1\|1323894_1325307_+	RNA helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	8.3e-51	31.8
AVU89725.1\|1325331_1325595_+	DUF3116 domain-containing protein	NA	NA	NA	NA
AVU89726.1\|1325762_1326239_+	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
AVU89727.1\|1326276_1326522_-	hypothetical protein	NA	NA	NA	NA
AVU89728.1\|1326518_1327724_-	MFS transporter	NA	NA	NA	NA
AVU89729.1\|1327720_1327930_-	hypothetical protein	NA	NA	NA	NA
AVU89730.1\|1327928_1328588_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
AVU89731.1\|1328629_1328824_-	hypothetical protein	NA	NA	NA	NA
AVU89732.1\|1328890_1329739_-	YitT family protein	NA	NA	NA	NA
AVU89733.1\|1330358_1331072_+	trehalose operon repressor	NA	NA	NA	NA
AVU89734.1\|1331102_1332749_-	alpha,alpha-phosphotrehalase	NA	NA	NA	NA
AVU89735.1\|1332767_1334252_-	PTS trehalose transporter subunit IIBC	NA	NA	NA	NA
AVU89736.1\|1334367_1334820_+	NUDIX domain-containing protein	NA	NA	NA	NA
AVU89737.1\|1334866_1335331_-	hypothetical protein	NA	NA	NA	NA
AVU89738.1\|1335519_1336440_+	alpha/beta hydrolase	NA	NA	NA	NA
AVU89739.1\|1336459_1337707_-	gamma-glutamyl-phosphate reductase	A0A1X9I5D4	Streptococcus_phage	1.2e-106	51.8
AVU89740.1\|1337690_1338521_-	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	4.3e-47	42.4
AVU89741.1\|1338656_1339796_-\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
AVU89742.1\|1339876_1340272_-	XRE family transcriptional regulator	A9D9J6	Lactobacillus_prophage	1.3e-14	57.4
AVU89743.1\|1340422_1340638_+	XRE family transcriptional regulator	NA	NA	NA	NA
AVU89744.1\|1340756_1341290_+	hypothetical protein	NA	NA	NA	NA
AVU89745.1\|1341307_1341973_+	hypothetical protein	NA	NA	NA	NA
AVU89746.1\|1342234_1343173_+	hypothetical protein	NA	NA	NA	NA
AVU89747.1\|1343287_1344571_+	trigger factor	NA	NA	NA	NA
AVU89748.1\|1344756_1346016_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.4e-145	63.2
AVU89749.1\|1346134_1346701_+	signal peptidase I	NA	NA	NA	NA
AVU89750.1\|1346735_1347305_+	signal peptidase I	NA	NA	NA	NA
AVU89751.1\|1347406_1347949_+	signal peptidase I	NA	NA	NA	NA
AVU89752.1\|1347958_1348822_+	ribosome biogenesis GTPase YlqF	NA	NA	NA	NA
AVU89753.1\|1348818_1349604_+	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	3.0e-26	39.2
AVU89754.1\|1349737_1350598_+	DNA-protecting protein DprA	NA	NA	NA	NA
AVU89755.1\|1350869_1352948_+	type I DNA topoisomerase	A0A1V0SB35	Catovirus	1.4e-107	37.7
AVU89756.1\|1353010_1354315_+\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA

DBSCAN-SWA_5

1818272 : 1865293

Erysipelothrix_phage(71.43%)

portal,protease,tail,capsid,holin,terminase,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU90179.1\|1818272_1819718_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	2.6e-140	56.0
AVU90180.1\|1819896_1820439_+	recombinase family protein	A0A219YB42	Aeromonas_phage	1.8e-17	30.2
AVU90181.1\|1820532_1822101_-	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	2.3e-166	59.4
AVU90182.1\|1822102_1822519_-	recombinase	NA	NA	NA	NA
AVU90183.1\|1822518_1824081_-	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	6.4e-137	48.4
AVU90184.1\|1824134_1824362_-	hypothetical protein	NA	NA	NA	NA
AVU90185.1\|1824501_1824846_+	ArsR family transcriptional regulator	A0A218MNF3	uncultured_virus	3.8e-10	40.6
AVU90186.1\|1824842_1826156_+	arsenical efflux pump membrane protein ArsB	A0A2H4PQU3	Staphylococcus_phage	4.4e-163	70.1
AVU90187.1\|1826171_1826573_+	arsenate reductase (thioredoxin)	A0A2H4PQT9	Staphylococcus_phage	2.1e-47	68.0
AVU90188.1\|1826688_1827882_-	ChrA protein	NA	NA	NA	NA
AVU90189.1\|1827893_1828202_-	PadR family transcriptional regulator	NA	NA	NA	NA
AVU90190.1\|1828398_1829106_-	amidase	H7BVK7	unidentified_phage	3.5e-42	41.3
AVU90191.1\|1829102_1829513_-\|holin	holin	A0A2K5B2A2	Erysipelothrix_phage	6.3e-52	69.1
AVU90192.1\|1829589_1832061_-	glycosyl hydrolase	A0A2K5B2A1	Erysipelothrix_phage	0.0e+00	64.6
AVU91355.1\|1832057_1832633_-	hypothetical protein	A0A2K5B2A0	Erysipelothrix_phage	1.3e-47	51.9
AVU90193.1\|1832648_1832843_-	hypothetical protein	A0A2K5B299	Erysipelothrix_phage	1.4e-14	55.4
AVU90194.1\|1832854_1835374_-	hypothetical protein	A0A2K5B298	Erysipelothrix_phage	3.6e-307	60.6
AVU90195.1\|1835381_1836155_-\|tail	phage tail family protein	A0A2I4R672	Erysipelothrix_phage	9.7e-70	47.3
AVU90196.1\|1836170_1838792_-\|tail	phage tail tape measure protein	B6CXF2	Clostridium_phage	4.3e-69	47.8
AVU90197.1\|1839051_1839438_-	hypothetical protein	A0A2K5B295	Erysipelothrix_phage	6.6e-35	64.3
AVU90198.1\|1839450_1840047_-\|tail	phage tail protein	A0A2K5B294	Erysipelothrix_phage	1.7e-82	77.4
AVU90199.1\|1840050_1840398_-	hypothetical protein	A0A2K5B293	Erysipelothrix_phage	9.2e-28	50.9
AVU90200.1\|1840394_1840826_-	hypothetical protein	A0A2K5B292	Erysipelothrix_phage	3.0e-44	62.2
AVU90201.1\|1840818_1841154_-\|head,tail	head-tail adaptor protein	A0A2K5B291	Erysipelothrix_phage	3.5e-24	51.4
AVU90202.1\|1841157_1841466_-\|head,tail	phage gp6-like head-tail connector protein	A0A2K5B290	Erysipelothrix_phage	5.4e-40	77.5
AVU90203.1\|1841480_1841708_-	Head fiber protein	A0A2K5B289	Erysipelothrix_phage	9.0e-16	64.0
AVU90204.1\|1841726_1842923_-\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	1.6e-156	68.1
AVU90205.1\|1842938_1843622_-\|protease	Clp protease ClpP	Q6DMU1	Streptococcus_phage	8.3e-73	62.8
AVU90206.1\|1843590_1844874_-\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	2.5e-187	78.3
AVU91356.1\|1844895_1846494_-\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	1.8e-243	77.7
AVU90207.1\|1846562_1847027_-	gamma-glutamylcyclotransferase	G3MAQ5	Bacillus_virus	1.4e-15	35.0
AVU90208.1\|1847069_1847969_-	amidoligase	A0A2K9V489	Faecalibacterium_phage	6.5e-49	38.6
AVU90209.1\|1848071_1848299_-	DUF4314 domain-containing protein	NA	NA	NA	NA
AVU90210.1\|1848295_1848946_-	virulence protein	A0A2K5B280	Erysipelothrix_phage	2.1e-41	45.0
AVU90211.1\|1849034_1850273_-	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	3.5e-170	68.4
AVU90212.1\|1850253_1851429_-	methionine adenosyltransferase	A0A2K5B278	Erysipelothrix_phage	4.1e-152	67.3
AVU90213.1\|1851447_1851999_-\|terminase	terminase	A0A2K5B277	Erysipelothrix_phage	1.5e-69	66.7
AVU90214.1\|1852104_1852470_-	HNH endonuclease	A0A2K5B276	Erysipelothrix_phage	1.9e-39	60.5
AVU90215.1\|1852684_1853143_-	hypothetical protein	NA	NA	NA	NA
AVU90216.1\|1853139_1854498_-	ATP-dependent helicase	A0A2K5B273	Erysipelothrix_phage	5.9e-155	66.0
AVU90217.1\|1854478_1854760_-	VRR-NUC domain-containing protein	A0A2K5B272	Erysipelothrix_phage	3.6e-22	55.6
AVU90218.1\|1855019_1857365_-	hypothetical protein	A0A2K5B271	Erysipelothrix_phage	5.9e-219	48.6
AVU91357.1\|1857383_1858160_-	phage antirepressor	A0A0B5A507	Paenibacillus_phage	6.6e-66	49.0
AVU90219.1\|1858252_1860187_-	hypothetical protein	A0A2K5B2B0	Erysipelothrix_phage	9.1e-242	63.4
AVU90220.1\|1860183_1860738_-	DUF2815 domain-containing protein	A0A2K5B2A9	Erysipelothrix_phage	3.6e-66	71.3
AVU90221.1\|1860740_1861871_-	DUF2800 domain-containing protein	A0A2K5B2A8	Erysipelothrix_phage	1.4e-141	65.0
AVU90222.1\|1861867_1862185_-	rRNA biogenesis protein rrp5	A0A2K5B2A7	Erysipelothrix_phage	1.3e-12	42.3
AVU90223.1\|1862186_1862390_-	hypothetical protein	NA	NA	NA	NA
AVU90224.1\|1862492_1862996_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
AVU90225.1\|1863403_1865293_-	XRE family transcriptional regulator	E4ZFJ9	Streptococcus_phage	1.2e-81	31.0

DBSCAN-SWA_6

1941088 : 1949374

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU90293.1\|1941088_1941655_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.0e-25	35.9
AVU90294.1\|1941651_1942701_-	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.7e-61	42.9
AVU90295.1\|1942719_1944147_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	1.1e-53	34.6
AVU90296.1\|1944131_1946351_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.3e-159	41.2
AVU90297.1\|1946343_1947027_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
AVU90298.1\|1947030_1947276_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
AVU90299.1\|1947287_1948001_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	2.3e-41	38.3
AVU90300.1\|1948081_1949374_-	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	7.2e-17	32.6

DBSCAN-SWA_7

2605893 : 2613737

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
AVU90919.1\|2605893_2606865_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	5.2e-52	39.4
AVU90920.1\|2606872_2607841_-	gluconeogenesis factor	A1IMD5	Streptococcus_phage	6.7e-68	43.3
AVU90921.1\|2607842_2608718_-	RNase adaptor protein RapZ	A0A0R8VB27	Thermobifida_phage	3.2e-08	29.7
AVU90922.1\|2608825_2610556_-	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	4.3e-174	53.3
AVU90923.1\|2610597_2611659_-	galactose mutarotase	NA	NA	NA	NA
AVU90924.1\|2611675_2612659_-	UDP-glucose 4-epimerase GalE	A0A2K9L1R4	Tupanvirus	2.6e-51	37.2
AVU90925.1\|2612777_2613737_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	2.0e-88	53.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. CP025561

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. CP025560

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection